id sid tid token lemma pos bjos-8674720 1 1 1 1 NUM bjos-8674720 1 2 volume volume NOUN bjos-8674720 1 3 23 23 NUM bjos-8674720 1 4 2024 2024 NUM bjos-8674720 1 5 e244720 e244720 NOUN bjos-8674720 1 6 original original ADJ bjos-8674720 1 7 research research NOUN bjos-8674720 1 8 braz braz PROPN bjos-8674720 1 9 j j PROPN bjos-8674720 1 10 oral oral PROPN bjos-8674720 1 11 sci sci PROPN bjos-8674720 1 12 . . PUNCT bjos-8674720 2 1 2024;23 2024;23 NUM bjos-8674720 2 2 : : PUNCT bjos-8674720 2 3 e244720http://dx.doi.org/10.20396 e244720http://dx.doi.org/10.20396 SYM bjos-8674720 2 4 / / SYM bjos-8674720 2 5 bjos.v23i00.8674720 bjos.v23i00.8674720 NOUN bjos-8674720 2 6 1 1 NUM bjos-8674720 2 7 periodontics periodontic NOUN bjos-8674720 2 8 division division NOUN bjos-8674720 2 9 , , PUNCT bjos-8674720 2 10 department department NOUN bjos-8674720 2 11 of of ADP bjos-8674720 2 12 prosthodontics prosthodontic NOUN bjos-8674720 2 13 and and CCONJ bjos-8674720 2 14 periodontics periodontic NOUN bjos-8674720 2 15 , , PUNCT bjos-8674720 2 16 faculdade faculdade NOUN bjos-8674720 2 17 de de X bjos-8674720 2 18 odontologia odontologia X bjos-8674720 2 19 de de X bjos-8674720 2 20 piracicaba piracicaba PROPN bjos-8674720 2 21 ( ( PUNCT bjos-8674720 2 22 fop fop ADJ bjos-8674720 2 23 ) ) PUNCT bjos-8674720 2 24 , , PUNCT bjos-8674720 2 25 universidade universidade PROPN bjos-8674720 2 26 estadual estadual PROPN bjos-8674720 2 27 de de PROPN bjos-8674720 2 28 campinas campinas PROPN bjos-8674720 2 29 ( ( PUNCT bjos-8674720 2 30 unicamp unicamp PROPN bjos-8674720 2 31 ) ) PUNCT bjos-8674720 2 32 , , PUNCT bjos-8674720 2 33 piracicaba piracicaba PROPN bjos-8674720 2 34 , , PUNCT bjos-8674720 2 35 são são PROPN bjos-8674720 2 36 paulo paulo PROPN bjos-8674720 2 37 , , PUNCT bjos-8674720 2 38 brazil brazil PROPN bjos-8674720 2 39 . . PUNCT bjos-8674720 3 1 2 2 NUM bjos-8674720 3 2 microbiology microbiology NOUN bjos-8674720 3 3 and and CCONJ bjos-8674720 3 4 immunology immunology NOUN bjos-8674720 3 5 division division NOUN bjos-8674720 3 6 , , PUNCT bjos-8674720 3 7 department department NOUN bjos-8674720 3 8 of of ADP bjos-8674720 3 9 biosciences bioscience NOUN bjos-8674720 3 10 and and CCONJ bjos-8674720 3 11 oral oral ADJ bjos-8674720 3 12 biopathology biopathology NOUN bjos-8674720 3 13 , , PUNCT bjos-8674720 3 14 são são PROPN bjos-8674720 3 15 josé josé PROPN bjos-8674720 3 16 dos dos PROPN bjos-8674720 3 17 campos campos PROPN bjos-8674720 3 18 school school PROPN bjos-8674720 3 19 of of ADP bjos-8674720 3 20 dentistry dentistry NOUN bjos-8674720 3 21 , , PUNCT bjos-8674720 3 22 são são PROPN bjos-8674720 3 23 paulo paulo PROPN bjos-8674720 3 24 state state PROPN bjos-8674720 3 25 university university PROPN bjos-8674720 3 26 , , PUNCT bjos-8674720 3 27 são são PROPN bjos-8674720 3 28 josé josé PROPN bjos-8674720 3 29 dos dos PROPN bjos-8674720 3 30 campos campos PROPN bjos-8674720 3 31 , , PUNCT bjos-8674720 3 32 brazil brazil PROPN bjos-8674720 3 33 . . PUNCT bjos-8674720 4 1 3 3 NUM bjos-8674720 4 2 periodontics periodontic NOUN bjos-8674720 4 3 division division NOUN bjos-8674720 4 4 , , PUNCT bjos-8674720 4 5 department department NOUN bjos-8674720 4 6 of of ADP bjos-8674720 4 7 diagnosis diagnosis NOUN bjos-8674720 4 8 and and CCONJ bjos-8674720 4 9 surgery surgery NOUN bjos-8674720 4 10 , , PUNCT bjos-8674720 4 11 são são PROPN bjos-8674720 4 12 josé josé PROPN bjos-8674720 4 13 dos dos PROPN bjos-8674720 4 14 campos campos PROPN bjos-8674720 4 15 school school PROPN bjos-8674720 4 16 of of ADP bjos-8674720 4 17 dentistry dentistry NOUN bjos-8674720 4 18 , , PUNCT bjos-8674720 4 19 são são PROPN bjos-8674720 4 20 paulo paulo PROPN bjos-8674720 4 21 state state PROPN bjos-8674720 4 22 university university PROPN bjos-8674720 4 23 , , PUNCT bjos-8674720 4 24 são são PROPN bjos-8674720 4 25 josé josé PROPN bjos-8674720 4 26 dos dos PROPN bjos-8674720 4 27 campos campos PROPN bjos-8674720 4 28 , , PUNCT bjos-8674720 4 29 brazil brazil PROPN bjos-8674720 4 30 . . PUNCT bjos-8674720 5 1 4 4 NUM bjos-8674720 5 2 department department NOUN bjos-8674720 5 3 of of ADP bjos-8674720 5 4 oral oral ADJ bjos-8674720 5 5 health health NOUN bjos-8674720 5 6 practice practice NOUN bjos-8674720 5 7 and and CCONJ bjos-8674720 5 8 center center NOUN bjos-8674720 5 9 of of ADP bjos-8674720 5 10 oral oral ADJ bjos-8674720 5 11 health health NOUN bjos-8674720 5 12 research research NOUN bjos-8674720 5 13 , , PUNCT bjos-8674720 5 14 university university PROPN bjos-8674720 5 15 of of ADP bjos-8674720 5 16 kentucky kentucky PROPN bjos-8674720 5 17 college college PROPN bjos-8674720 5 18 of of ADP bjos-8674720 5 19 dentistry dentistry PROPN bjos-8674720 5 20 , , PUNCT bjos-8674720 5 21 lexington lexington PROPN bjos-8674720 5 22 , , PUNCT bjos-8674720 5 23 kentucky kentucky PROPN bjos-8674720 5 24 , , PUNCT bjos-8674720 5 25 usa usa PROPN bjos-8674720 5 26 corresponding corresponding PROPN bjos-8674720 5 27 author author NOUN bjos-8674720 5 28 : : PUNCT bjos-8674720 5 29 renato renato PROPN bjos-8674720 5 30 corrêa corrêa PROPN bjos-8674720 5 31 viana viana PROPN bjos-8674720 5 32 casarin casarin PROPN bjos-8674720 5 33 division division NOUN bjos-8674720 5 34 of of ADP bjos-8674720 5 35 periodontology periodontology NOUN bjos-8674720 5 36 , , PUNCT bjos-8674720 5 37 department department NOUN bjos-8674720 5 38 of of ADP bjos-8674720 5 39 prosthodontic prosthodontic ADJ bjos-8674720 5 40 and and CCONJ bjos-8674720 5 41 periodontics periodontic NOUN bjos-8674720 5 42 piracicaba piracicaba VERB bjos-8674720 5 43 dental dental ADJ bjos-8674720 5 44 school school NOUN bjos-8674720 5 45 , , PUNCT bjos-8674720 5 46 university university PROPN bjos-8674720 5 47 of of ADP bjos-8674720 5 48 campinas campinas PROPN bjos-8674720 5 49 unicamp unicamp PROPN bjos-8674720 5 50 avenida avenida PROPN bjos-8674720 5 51 limeira limeira PROPN bjos-8674720 5 52 , , PUNCT bjos-8674720 5 53 901 901 NUM bjos-8674720 5 54 – – PUNCT bjos-8674720 5 55 areião areião NOUN bjos-8674720 5 56 , , PUNCT bjos-8674720 5 57 piracicaba piracicaba PROPN bjos-8674720 5 58 , , PUNCT bjos-8674720 5 59 sp sp NOUN bjos-8674720 5 60 , , PUNCT bjos-8674720 5 61 brazil brazil PROPN bjos-8674720 5 62 . . PUNCT bjos-8674720 6 1 zc zc PROPN bjos-8674720 6 2 13414 13414 NUM bjos-8674720 6 3 - - SYM bjos-8674720 6 4 903 903 NUM bjos-8674720 6 5 phone phone NOUN bjos-8674720 6 6 : : PUNCT bjos-8674720 6 7 ( ( PUNCT bjos-8674720 6 8 19 19 NUM bjos-8674720 6 9 ) ) PUNCT bjos-8674720 6 10 2106 2106 NUM bjos-8674720 6 11 - - SYM bjos-8674720 6 12 5301 5301 NUM bjos-8674720 6 13 email email NOUN bjos-8674720 6 14 : : PUNCT bjos-8674720 6 15 rcasarin@unicamp.br rcasarin@unicamp.br NOUN bjos-8674720 6 16 editor editor NOUN bjos-8674720 6 17 : : PUNCT bjos-8674720 6 18 dr dr PROPN bjos-8674720 6 19 . . PROPN bjos-8674720 6 20 altair altair PROPN bjos-8674720 6 21 a. a. PROPN bjos-8674720 6 22 del del PROPN bjos-8674720 6 23 bel bel PROPN bjos-8674720 6 24 cury cury PROPN bjos-8674720 6 25 received receive VERB bjos-8674720 6 26 : : PUNCT bjos-8674720 6 27 october october PROPN bjos-8674720 6 28 3 3 NUM bjos-8674720 6 29 , , PUNCT bjos-8674720 6 30 2023 2023 NUM bjos-8674720 6 31 accepted accept VERB bjos-8674720 6 32 : : PUNCT bjos-8674720 6 33 january january PROPN bjos-8674720 6 34 29 29 NUM bjos-8674720 6 35 , , PUNCT bjos-8674720 6 36 2024 2024 NUM bjos-8674720 6 37 impact impact NOUN bjos-8674720 6 38 of of ADP bjos-8674720 6 39 aggregatibacter aggregatibacter ADJ bjos-8674720 6 40 actinomycetemcomitans actinomycetemcomitan NOUN bjos-8674720 6 41 on on ADP bjos-8674720 6 42 epithelial epithelial ADJ bjos-8674720 6 43 repair repair NOUN bjos-8674720 6 44 : : PUNCT bjos-8674720 6 45 in in ADP bjos-8674720 6 46 vitro vitro X bjos-8674720 6 47 study study NOUN bjos-8674720 6 48 in in ADP bjos-8674720 6 49 wound wound NOUN bjos-8674720 6 50 model model NOUN bjos-8674720 6 51 bianca bianca PROPN bjos-8674720 6 52 carvalho carvalho PROPN bjos-8674720 6 53 mendes¹ mendes¹ PROPN bjos-8674720 6 54 , , PUNCT bjos-8674720 6 55 camila camila PROPN bjos-8674720 6 56 schmidt schmidt PROPN bjos-8674720 6 57 stolf1 stolf1 PROPN bjos-8674720 6 58 , , PUNCT bjos-8674720 6 59 hélvis hélvis PROPN bjos-8674720 6 60 enri enri PROPN bjos-8674720 6 61 de de PROPN bjos-8674720 6 62 sousa sousa PROPN bjos-8674720 6 63 paz1 paz1 PROPN bjos-8674720 6 64 , , PUNCT bjos-8674720 6 65 letícia letícia NOUN bjos-8674720 6 66 sandoli sandoli VERB bjos-8674720 6 67 arroteia1 arroteia1 NOUN bjos-8674720 6 68 , , PUNCT bjos-8674720 6 69 lucas lucas PROPN bjos-8674720 6 70 de de PROPN bjos-8674720 6 71 paula paula PROPN bjos-8674720 6 72 ramos2 ramos2 PROPN bjos-8674720 6 73 , , PUNCT bjos-8674720 6 74 mauro mauro PROPN bjos-8674720 6 75 pedrine pedrine PROPN bjos-8674720 6 76 santamaria3,4 santamaria3,4 PROPN bjos-8674720 6 77 , , PUNCT bjos-8674720 6 78 karina karina PROPN bjos-8674720 6 79 gonzales gonzales PROPN bjos-8674720 6 80 silvério silvério PROPN bjos-8674720 6 81 ruiz1 ruiz1 PROPN bjos-8674720 6 82 , , PUNCT bjos-8674720 6 83 mabelle mabelle NOUN bjos-8674720 6 84 de de ADP bjos-8674720 6 85 freitas freitas PROPN bjos-8674720 6 86 monteiro1 monteiro1 PROPN bjos-8674720 6 87 , , PUNCT bjos-8674720 6 88 renato renato PROPN bjos-8674720 6 89 corrêa corrêa PROPN bjos-8674720 6 90 viana viana PROPN bjos-8674720 6 91 casarin1 casarin1 PROPN bjos-8674720 6 92 * * PUNCT bjos-8674720 6 93 abstract abstract ADJ bjos-8674720 6 94 : : PUNCT bjos-8674720 6 95 normal normal ADJ bjos-8674720 6 96 wound wound NOUN bjos-8674720 6 97 healing healing NOUN bjos-8674720 6 98 occurs occur VERB bjos-8674720 6 99 in in ADP bjos-8674720 6 100 four four NUM bjos-8674720 6 101 overlapping overlap VERB bjos-8674720 6 102 stages stage NOUN bjos-8674720 6 103 hemostasis hemostasis NOUN bjos-8674720 6 104 , , PUNCT bjos-8674720 6 105 inflammation inflammation NOUN bjos-8674720 6 106 , , PUNCT bjos-8674720 6 107 proliferation proliferation NOUN bjos-8674720 6 108 , , PUNCT bjos-8674720 6 109 and and CCONJ bjos-8674720 6 110 remodeling remodeling NOUN bjos-8674720 6 111 . . PUNCT bjos-8674720 7 1 in in ADP bjos-8674720 7 2 the the DET bjos-8674720 7 3 oral oral ADJ bjos-8674720 7 4 cavity cavity NOUN bjos-8674720 7 5 , , PUNCT bjos-8674720 7 6 these these DET bjos-8674720 7 7 processes process NOUN bjos-8674720 7 8 occur occur VERB bjos-8674720 7 9 in in ADP bjos-8674720 7 10 an an DET bjos-8674720 7 11 infectious infectious ADJ bjos-8674720 7 12 environment environment NOUN bjos-8674720 7 13 . . PUNCT bjos-8674720 8 1 among among ADP bjos-8674720 8 2 the the DET bjos-8674720 8 3 pathogens pathogen NOUN bjos-8674720 8 4 found find VERB bjos-8674720 8 5 in in ADP bjos-8674720 8 6 the the DET bjos-8674720 8 7 oral oral ADJ bjos-8674720 8 8 community community NOUN bjos-8674720 8 9 , , PUNCT bjos-8674720 8 10 aggregatibacter aggregatibacter NOUN bjos-8674720 8 11 actinomycetemcomitans actinomycetemcomitan NOUN bjos-8674720 8 12 ( ( PUNCT bjos-8674720 8 13 aa aa NOUN bjos-8674720 8 14 ) ) PUNCT bjos-8674720 8 15 constitutes constitute VERB bjos-8674720 8 16 a a DET bjos-8674720 8 17 well well ADV bjos-8674720 8 18 - - PUNCT bjos-8674720 8 19 recognized recognize VERB bjos-8674720 8 20 periodontal periodontal ADJ bjos-8674720 8 21 pathogen pathogen NOUN bjos-8674720 8 22 responsible responsible ADJ bjos-8674720 8 23 for for ADP bjos-8674720 8 24 expressing express VERB bjos-8674720 8 25 several several ADJ bjos-8674720 8 26 virulence virulence NOUN bjos-8674720 8 27 factors factor NOUN bjos-8674720 8 28 , , PUNCT bjos-8674720 8 29 which which PRON bjos-8674720 8 30 activate activate VERB bjos-8674720 8 31 a a DET bjos-8674720 8 32 host host NOUN bjos-8674720 8 33 response response NOUN bjos-8674720 8 34 . . PUNCT bjos-8674720 9 1 aim aim VERB bjos-8674720 9 2 : : PUNCT bjos-8674720 9 3 this this DET bjos-8674720 9 4 study study NOUN bjos-8674720 9 5 investigated investigate VERB bjos-8674720 9 6 whether whether SCONJ bjos-8674720 9 7 aa aa PROPN bjos-8674720 9 8 ’s ’s ADJ bjos-8674720 9 9 presence presence NOUN bjos-8674720 9 10 can can AUX bjos-8674720 9 11 interfere interfere VERB bjos-8674720 9 12 with with ADP bjos-8674720 9 13 oral oral ADJ bjos-8674720 9 14 keratinocyte keratinocyte NOUN bjos-8674720 9 15 tissue tissue NOUN bjos-8674720 9 16 healing healing NOUN bjos-8674720 9 17 in in ADP bjos-8674720 9 18 an an DET bjos-8674720 9 19 in in ADP bjos-8674720 9 20 vitro vitro X bjos-8674720 9 21 wound wound ADJ bjos-8674720 9 22 healing healing NOUN bjos-8674720 9 23 model model NOUN bjos-8674720 9 24 . . PUNCT bjos-8674720 10 1 methods method NOUN bjos-8674720 10 2 : : PUNCT bjos-8674720 10 3 two two NUM bjos-8674720 10 4 groups group NOUN bjos-8674720 10 5 were be AUX bjos-8674720 10 6 defined define VERB bjos-8674720 10 7 : : PUNCT bjos-8674720 10 8 group group NOUN bjos-8674720 10 9 ko ko PROPN bjos-8674720 10 10 ( ( PUNCT bjos-8674720 10 11 n=5 n=5 PROPN bjos-8674720 10 12 ) ) PUNCT bjos-8674720 10 13 and and CCONJ bjos-8674720 10 14 group group NOUN bjos-8674720 10 15 ko+aa ko+aa PROPN bjos-8674720 10 16 ( ( PUNCT bjos-8674720 10 17 n=5 n=5 PROPN bjos-8674720 10 18 ) ) PUNCT bjos-8674720 10 19 . . PUNCT bjos-8674720 11 1 the the DET bjos-8674720 11 2 aa aa PROPN bjos-8674720 11 3 ( ( PUNCT bjos-8674720 11 4 jp2 jp2 PROPN bjos-8674720 11 5 strains strain NOUN bjos-8674720 11 6 ) ) PUNCT bjos-8674720 11 7 were be AUX bjos-8674720 11 8 cultivated cultivate VERB bjos-8674720 11 9 in in ADP bjos-8674720 11 10 anaerobiosis anaerobiosis NOUN bjos-8674720 11 11 , , PUNCT bjos-8674720 11 12 and and CCONJ bjos-8674720 11 13 the the DET bjos-8674720 11 14 total total ADJ bjos-8674720 11 15 protein protein NOUN bjos-8674720 11 16 extract extract NOUN bjos-8674720 11 17 was be AUX bjos-8674720 11 18 obtained obtain VERB bjos-8674720 11 19 . . PUNCT bjos-8674720 12 1 the the DET bjos-8674720 12 2 keratinocytes keratinocyte NOUN bjos-8674720 12 3 were be AUX bjos-8674720 12 4 cultivated cultivate VERB bjos-8674720 12 5 with with ADP bjos-8674720 12 6 the the DET bjos-8674720 12 7 medium medium NOUN bjos-8674720 12 8 of of ADP bjos-8674720 12 9 standard standard ADJ bjos-8674720 12 10 culture culture NOUN bjos-8674720 12 11 until until ADP bjos-8674720 12 12 their their PRON bjos-8674720 12 13 confluence confluence NOUN bjos-8674720 12 14 . . PUNCT bjos-8674720 13 1 after after ADP bjos-8674720 13 2 confluence confluence NOUN bjos-8674720 13 3 , , PUNCT bjos-8674720 13 4 plates plate NOUN bjos-8674720 13 5 were be AUX bjos-8674720 13 6 allocated allocate VERB bjos-8674720 13 7 to to ADP bjos-8674720 13 8 each each DET bjos-8674720 13 9 group group NOUN bjos-8674720 13 10 . . PUNCT bjos-8674720 14 1 with with ADP bjos-8674720 14 2 the the DET bjos-8674720 14 3 pipette pipette NOUN bjos-8674720 14 4 ’s ’s PART bjos-8674720 14 5 tip tip NOUN bjos-8674720 14 6 , , PUNCT bjos-8674720 14 7 a a DET bjos-8674720 14 8 “ " PUNCT bjos-8674720 14 9 scratch scratch NOUN bjos-8674720 14 10 ” " PUNCT bjos-8674720 14 11 was be AUX bjos-8674720 14 12 made make VERB bjos-8674720 14 13 in in ADP bjos-8674720 14 14 the the DET bjos-8674720 14 15 middle middle NOUN bjos-8674720 14 16 of of ADP bjos-8674720 14 17 each each DET bjos-8674720 14 18 well well NOUN bjos-8674720 14 19 of of ADP bjos-8674720 14 20 the the DET bjos-8674720 14 21 plate plate NOUN bjos-8674720 14 22 , , PUNCT bjos-8674720 14 23 and and CCONJ bjos-8674720 14 24 the the DET bjos-8674720 14 25 cells cell NOUN bjos-8674720 14 26 were be AUX bjos-8674720 14 27 cultured cultured ADJ bjos-8674720 14 28 at at ADP bjos-8674720 14 29 37 37 NUM bjos-8674720 14 30 ° ° ADP bjos-8674720 14 31 c c NOUN bjos-8674720 14 32 in in ADP bjos-8674720 14 33 a a DET bjos-8674720 14 34 humidified humidify VERB bjos-8674720 14 35 atmosphere atmosphere NOUN bjos-8674720 14 36 with with ADP bjos-8674720 14 37 5 5 NUM bjos-8674720 14 38 % % NOUN bjos-8674720 14 39 co2 co2 NOUN bjos-8674720 14 40 . . PUNCT bjos-8674720 15 1 the the DET bjos-8674720 15 2 cells cell NOUN bjos-8674720 15 3 received receive VERB bjos-8674720 15 4 the the DET bjos-8674720 15 5 stimulus stimulus NOUN bjos-8674720 15 6 according accord VERB bjos-8674720 15 7 to to ADP bjos-8674720 15 8 groups group NOUN bjos-8674720 15 9 , , PUNCT bjos-8674720 15 10 and and CCONJ bjos-8674720 15 11 , , PUNCT bjos-8674720 15 12 at at ADP bjos-8674720 15 13 times time NOUN bjos-8674720 15 14 0 0 NUM bjos-8674720 15 15 , , PUNCT bjos-8674720 15 16 5 5 NUM bjos-8674720 15 17 , , PUNCT bjos-8674720 15 18 10 10 NUM bjos-8674720 15 19 , , PUNCT bjos-8674720 15 20 24 24 NUM bjos-8674720 15 21 , , PUNCT bjos-8674720 15 22 and and CCONJ bjos-8674720 15 23 48 48 NUM bjos-8674720 15 24 hours hour NOUN bjos-8674720 15 25 , , PUNCT bjos-8674720 15 26 the the DET bjos-8674720 15 27 wound wound NOUN bjos-8674720 15 28 areas area NOUN bjos-8674720 15 29 were be AUX bjos-8674720 15 30 visualized visualize VERB bjos-8674720 15 31 and and CCONJ bjos-8674720 15 32 standardly standardly ADV bjos-8674720 15 33 recorded record VERB bjos-8674720 15 34 using use VERB bjos-8674720 15 35 an an DET bjos-8674720 15 36 inverted inverted ADJ bjos-8674720 15 37 microscope microscope NOUN bjos-8674720 15 38 . . PUNCT bjos-8674720 16 1 results result NOUN bjos-8674720 16 2 : : PUNCT bjos-8674720 16 3 when when SCONJ bjos-8674720 16 4 analyzing analyze VERB bjos-8674720 16 5 the the DET bjos-8674720 16 6 timeframe timeframe NOUN bjos-8674720 16 7 , , PUNCT bjos-8674720 16 8 differences difference NOUN bjos-8674720 16 9 in in ADP bjos-8674720 16 10 wound wound ADJ bjos-8674720 16 11 measurements measurement NOUN bjos-8674720 16 12 indicate indicate VERB bjos-8674720 16 13 a a DET bjos-8674720 16 14 faster fast ADJ bjos-8674720 16 15 closure closure NOUN bjos-8674720 16 16 in in ADP bjos-8674720 16 17 the the DET bjos-8674720 16 18 control control NOUN bjos-8674720 16 19 group group NOUN bjos-8674720 16 20 compared compare VERB bjos-8674720 16 21 to to ADP bjos-8674720 16 22 the the DET bjos-8674720 16 23 ko+aa ko+aa PROPN bjos-8674720 16 24 group group NOUN bjos-8674720 16 25 , , PUNCT bjos-8674720 16 26 although although SCONJ bjos-8674720 16 27 not not PART bjos-8674720 16 28 statistically statistically ADV bjos-8674720 16 29 significant significant ADJ bjos-8674720 16 30 . . PUNCT bjos-8674720 17 1 however however ADV bjos-8674720 17 2 , , PUNCT bjos-8674720 17 3 upon upon SCONJ bjos-8674720 17 4 examining examine VERB bjos-8674720 17 5 the the DET bjos-8674720 17 6 wound wound NOUN bjos-8674720 17 7 closure closure NOUN bjos-8674720 17 8 measures measure NOUN bjos-8674720 17 9 , , PUNCT bjos-8674720 17 10 it it PRON bjos-8674720 17 11 was be AUX bjos-8674720 17 12 observed observe VERB bjos-8674720 17 13 that that SCONJ bjos-8674720 17 14 the the DET bjos-8674720 17 15 aa aa PROPN bjos-8674720 17 16 protein protein NOUN bjos-8674720 17 17 extract extract NOUN bjos-8674720 17 18 significantly significantly ADV bjos-8674720 17 19 reduced reduce VERB bjos-8674720 17 20 wound wound NOUN bjos-8674720 17 21 closure closure NOUN bjos-8674720 17 22 at at ADP bjos-8674720 17 23 10 10 NUM bjos-8674720 17 24 and and CCONJ bjos-8674720 17 25 48 48 NUM bjos-8674720 17 26 hours hour NOUN bjos-8674720 17 27 ( ( PUNCT bjos-8674720 17 28 p<0.05 p<0.05 NOUN bjos-8674720 17 29 ) ) PUNCT bjos-8674720 17 30 , , PUNCT bjos-8674720 17 31 negatively negatively ADV bjos-8674720 17 32 impacting impact VERB bjos-8674720 17 33 the the DET bjos-8674720 17 34 keratinocyte keratinocyte NOUN bjos-8674720 17 35 ’s ’s PART bjos-8674720 17 36 behavior behavior NOUN bjos-8674720 17 37 . . PUNCT bjos-8674720 18 1 conclusion conclusion NOUN bjos-8674720 18 2 : : PUNCT bjos-8674720 18 3 in in ADP bjos-8674720 18 4 summary summary NOUN bjos-8674720 18 5 , , PUNCT bjos-8674720 18 6 it it PRON bjos-8674720 18 7 was be AUX bjos-8674720 18 8 demonstrated demonstrate VERB bjos-8674720 18 9 that that SCONJ bjos-8674720 18 10 the the DET bjos-8674720 18 11 pathogen pathogen NOUN bjos-8674720 18 12 aa aa NOUN bjos-8674720 18 13 can can AUX bjos-8674720 18 14 interfere interfere VERB bjos-8674720 18 15 with with ADP bjos-8674720 18 16 the the DET bjos-8674720 18 17 re re NOUN bjos-8674720 18 18 - - NOUN bjos-8674720 18 19 epithelization epithelization NOUN bjos-8674720 18 20 in in ADP bjos-8674720 18 21 vitro vitro X bjos-8674720 18 22 . . PUNCT bjos-8674720 19 1 keywords keyword NOUN bjos-8674720 19 2 : : PUNCT bjos-8674720 19 3 wound wound ADJ bjos-8674720 19 4 healing healing NOUN bjos-8674720 19 5 . . PUNCT bjos-8674720 20 1 microbiota microbiota NOUN bjos-8674720 20 2 . . PUNCT bjos-8674720 21 1 keratinocytes keratinocyte NOUN bjos-8674720 21 2 . . PUNCT bjos-8674720 22 1 hacat hacat PROPN bjos-8674720 22 2 cells cell NOUN bjos-8674720 22 3 . . PUNCT bjos-8674720 23 1 http://dx.doi.org/10.20396/bjos.v23i00.8674720 http://dx.doi.org/10.20396/bjos.v23i00.8674720 NOUN bjos-8674720 23 2 mailto:rcasarin@unicamp.br mailto:rcasarin@unicamp.br NOUN bjos-8674720 23 3 https://orcid.org/0000-0002-5125-2326 https://orcid.org/0000-0002-5125-2326 NOUN bjos-8674720 23 4 https://orcid.org/0000-0002-0619-2547 https://orcid.org/0000-0002-0619-2547 INTJ bjos-8674720 23 5 https://orcid.org/0000-0003-2675-9675 https://orcid.org/0000-0003-2675-9675 INTJ bjos-8674720 23 6 https://orcid.org/0000-0002-2682-2796 https://orcid.org/0000-0002-2682-2796 PROPN bjos-8674720 23 7 https://orcid.org/0000-0001-9468-0729 https://orcid.org/0000-0001-9468-0729 PROPN bjos-8674720 23 8 https://orcid.org/0000-0001-5879-9095 https://orcid.org/0000-0001-5879-9095 PROPN bjos-8674720 23 9 https://orcid.org/0000-0001-9333-4349 https://orcid.org/0000-0001-9333-4349 PROPN bjos-8674720 23 10 https://orcid.org/0000-0003-1743-5855 https://orcid.org/0000-0003-1743-5855 PROPN bjos-8674720 23 11 2 2 NUM bjos-8674720 23 12 mendes mende NOUN bjos-8674720 24 1 et et PROPN bjos-8674720 24 2 al al PROPN bjos-8674720 24 3 . . PROPN bjos-8674720 24 4 braz braz PROPN bjos-8674720 24 5 j j PROPN bjos-8674720 24 6 oral oral PROPN bjos-8674720 24 7 sci sci PROPN bjos-8674720 24 8 . . PUNCT bjos-8674720 25 1 2024;23 2024;23 NUM bjos-8674720 25 2 : : PUNCT bjos-8674720 25 3 e244720 e244720 NOUN bjos-8674720 25 4 introduction introduction NOUN bjos-8674720 25 5 normal normal ADJ bjos-8674720 25 6 wound wound NOUN bjos-8674720 25 7 healing healing NOUN bjos-8674720 25 8 involves involve VERB bjos-8674720 25 9 four four NUM bjos-8674720 25 10 overlapping overlap VERB bjos-8674720 25 11 stages stage NOUN bjos-8674720 25 12 : : PUNCT bjos-8674720 25 13 hemostasis hemostasis NOUN bjos-8674720 25 14 , , PUNCT bjos-8674720 25 15 inflammation inflammation NOUN bjos-8674720 25 16 , , PUNCT bjos-8674720 25 17 proliferation proliferation NOUN bjos-8674720 25 18 , , PUNCT bjos-8674720 25 19 and and CCONJ bjos-8674720 25 20 remodeling1,2,3 remodeling1,2,3 PROPN bjos-8674720 25 21 . . PUNCT bjos-8674720 26 1 hemostasis hemostasis NOUN bjos-8674720 26 2 initiates initiate VERB bjos-8674720 26 3 healing healing NOUN bjos-8674720 26 4 by by ADP bjos-8674720 26 5 forming form VERB bjos-8674720 26 6 a a DET bjos-8674720 26 7 blood blood NOUN bjos-8674720 26 8 clot clot NOUN bjos-8674720 26 9 that that PRON bjos-8674720 26 10 initially initially ADV bjos-8674720 26 11 seals seal VERB bjos-8674720 26 12 the the DET bjos-8674720 26 13 wound wound NOUN bjos-8674720 26 14 . . PUNCT bjos-8674720 27 1 afterward afterward ADV bjos-8674720 27 2 , , PUNCT bjos-8674720 27 3 platelets platelet NOUN bjos-8674720 27 4 and and CCONJ bjos-8674720 27 5 inflammatory inflammatory ADJ bjos-8674720 27 6 cells cell NOUN bjos-8674720 27 7 arrive arrive VERB bjos-8674720 27 8 at at ADP bjos-8674720 27 9 the the DET bjos-8674720 27 10 site site NOUN bjos-8674720 27 11 primarily primarily ADV bjos-8674720 27 12 . . PUNCT bjos-8674720 28 1 they they PRON bjos-8674720 28 2 provide provide VERB bjos-8674720 28 3 essential essential ADJ bjos-8674720 28 4 functions function NOUN bjos-8674720 28 5 and and CCONJ bjos-8674720 28 6 signals signal NOUN bjos-8674720 28 7 for for ADP bjos-8674720 28 8 the the DET bjos-8674720 28 9 influx influx NOUN bjos-8674720 28 10 of of ADP bjos-8674720 28 11 important important ADJ bjos-8674720 28 12 cells cell NOUN bjos-8674720 28 13 , , PUNCT bjos-8674720 28 14 such such ADJ bjos-8674720 28 15 as as ADP bjos-8674720 28 16 fibroblasts fibroblast NOUN bjos-8674720 28 17 and and CCONJ bjos-8674720 28 18 endothelial endothelial ADJ bjos-8674720 28 19 cells cell NOUN bjos-8674720 28 20 , , PUNCT bjos-8674720 28 21 to to ADP bjos-8674720 28 22 the the DET bjos-8674720 28 23 injury injury NOUN bjos-8674720 28 24 site1 site1 PROPN bjos-8674720 28 25 . . PUNCT bjos-8674720 29 1 for for SCONJ bjos-8674720 29 2 healing healing NOUN bjos-8674720 29 3 to to PART bjos-8674720 29 4 occur occur VERB bjos-8674720 29 5 satisfactorily satisfactorily ADV bjos-8674720 29 6 , , PUNCT bjos-8674720 29 7 restoring restore VERB bjos-8674720 29 8 the the DET bjos-8674720 29 9 intact intact ADJ bjos-8674720 29 10 epidermal epidermal ADJ bjos-8674720 29 11 barrier barrier NOUN bjos-8674720 29 12 through through ADP bjos-8674720 29 13 re re NOUN bjos-8674720 29 14 - - NOUN bjos-8674720 29 15 epithelialization epithelialization NOUN bjos-8674720 29 16 is be AUX bjos-8674720 29 17 necessary necessary ADJ bjos-8674720 29 18 . . PUNCT bjos-8674720 30 1 for for ADP bjos-8674720 30 2 that that PRON bjos-8674720 30 3 , , PUNCT bjos-8674720 30 4 it it PRON bjos-8674720 30 5 is be AUX bjos-8674720 30 6 important important ADJ bjos-8674720 30 7 to to PART bjos-8674720 30 8 have have VERB bjos-8674720 30 9 the the DET bjos-8674720 30 10 directed direct VERB bjos-8674720 30 11 migration migration NOUN bjos-8674720 30 12 of of ADP bjos-8674720 30 13 keratinocytes keratinocyte NOUN bjos-8674720 30 14 and and CCONJ bjos-8674720 30 15 their their PRON bjos-8674720 30 16 proliferation proliferation NOUN bjos-8674720 30 17 and and CCONJ bjos-8674720 30 18 survival survival NOUN bjos-8674720 30 19 , , PUNCT bjos-8674720 30 20 as as SCONJ bjos-8674720 30 21 they they PRON bjos-8674720 30 22 are be AUX bjos-8674720 30 23 critical critical ADJ bjos-8674720 30 24 for for ADP bjos-8674720 30 25 the the DET bjos-8674720 30 26 re re NOUN bjos-8674720 30 27 - - NOUN bjos-8674720 30 28 epithelialization epithelialization NOUN bjos-8674720 30 29 of of ADP bjos-8674720 30 30 the the DET bjos-8674720 30 31 wound4 wound4 PROPN bjos-8674720 30 32 . . PUNCT bjos-8674720 31 1 several several ADJ bjos-8674720 31 2 diseases disease NOUN bjos-8674720 31 3 in in ADP bjos-8674720 31 4 the the DET bjos-8674720 31 5 oral oral ADJ bjos-8674720 31 6 cavity cavity NOUN bjos-8674720 31 7 and and CCONJ bjos-8674720 31 8 their their PRON bjos-8674720 31 9 treatments treatment NOUN bjos-8674720 31 10 led lead VERB bjos-8674720 31 11 to to ADP bjos-8674720 31 12 wounds wound NOUN bjos-8674720 31 13 that that PRON bjos-8674720 31 14 should should AUX bjos-8674720 31 15 heal heal VERB bjos-8674720 31 16 under under ADP bjos-8674720 31 17 an an DET bjos-8674720 31 18 infective infective ADJ bjos-8674720 31 19 condition condition NOUN bjos-8674720 31 20 . . PUNCT bjos-8674720 32 1 the the DET bjos-8674720 32 2 oral oral ADJ bjos-8674720 32 3 community community NOUN bjos-8674720 32 4 harbors harbor VERB bjos-8674720 32 5 more more ADJ bjos-8674720 32 6 than than ADP bjos-8674720 32 7 500 500 NUM bjos-8674720 32 8 cultured cultured ADJ bjos-8674720 32 9 and and CCONJ bjos-8674720 32 10 not not PART bjos-8674720 32 11 - - PUNCT bjos-8674720 32 12 yet yet ADV bjos-8674720 32 13 - - PUNCT bjos-8674720 32 14 cultivated cultivate VERB bjos-8674720 32 15 species5 species5 NOUN bjos-8674720 32 16 . . PUNCT bjos-8674720 33 1 some some PRON bjos-8674720 33 2 presented present VERB bjos-8674720 33 3 cytotoxic cytotoxic ADJ bjos-8674720 33 4 factors factor NOUN bjos-8674720 33 5 that that PRON bjos-8674720 33 6 could could AUX bjos-8674720 33 7 affect affect VERB bjos-8674720 33 8 healing healing NOUN bjos-8674720 33 9 processes process NOUN bjos-8674720 33 10 . . PUNCT bjos-8674720 33 11     SPACE bjos-8674720 33 12 among among ADP bjos-8674720 33 13 these these DET bjos-8674720 33 14 species specie NOUN bjos-8674720 33 15 , , PUNCT bjos-8674720 33 16 some some PRON bjos-8674720 33 17 of of ADP bjos-8674720 33 18 them they PRON bjos-8674720 33 19 are be AUX bjos-8674720 33 20 well well ADV bjos-8674720 33 21 - - PUNCT bjos-8674720 33 22 known know VERB bjos-8674720 33 23 pathogens pathogen NOUN bjos-8674720 33 24 , , PUNCT bjos-8674720 33 25 presenting present VERB bjos-8674720 33 26 diverse diverse ADJ bjos-8674720 33 27 virulence virulence NOUN bjos-8674720 33 28 factors factor NOUN bjos-8674720 33 29 , , PUNCT bjos-8674720 33 30 as as SCONJ bjos-8674720 33 31 aggregatibacter aggregatibacter PROPN bjos-8674720 33 32 actinomycetemcomitan actinomycetemcomitan PROPN bjos-8674720 33 33 ( ( PUNCT bjos-8674720 33 34 aa aa PROPN bjos-8674720 33 35 ) ) PUNCT bjos-8674720 33 36 , , PUNCT bjos-8674720 33 37 fusobacterium fusobacterium NOUN bjos-8674720 33 38 nucleatum nucleatum NOUN bjos-8674720 33 39 ( ( PUNCT bjos-8674720 33 40 fn fn NOUN bjos-8674720 33 41 ) ) PUNCT bjos-8674720 33 42 , , PUNCT bjos-8674720 33 43 tannerella tannerella NOUN bjos-8674720 33 44 forsythia forsythia NOUN bjos-8674720 33 45 ( ( PUNCT bjos-8674720 33 46 tf tf PROPN bjos-8674720 33 47 ) ) PUNCT bjos-8674720 33 48 , , PUNCT bjos-8674720 33 49 porphyromonas porphyromona NOUN bjos-8674720 33 50 gingivalis gingivalis PROPN bjos-8674720 33 51 ( ( PUNCT bjos-8674720 33 52 pg pg NOUN bjos-8674720 33 53 ) ) PUNCT bjos-8674720 33 54 , , PUNCT bjos-8674720 33 55 prevotella prevotella NOUN bjos-8674720 33 56 intermedia intermedia PROPN bjos-8674720 33 57 ( ( PUNCT bjos-8674720 33 58 pi pi NOUN bjos-8674720 33 59 ) ) PUNCT bjos-8674720 33 60 and and CCONJ bjos-8674720 33 61 treponema treponema VERB bjos-8674720 33 62 denticola denticola NOUN bjos-8674720 33 63 ( ( PUNCT bjos-8674720 33 64 td)6 td)6 PROPN bjos-8674720 33 65 . . PUNCT bjos-8674720 34 1 aa aa PROPN bjos-8674720 34 2 is be AUX bjos-8674720 34 3 a a DET bjos-8674720 34 4 well well ADV bjos-8674720 34 5 - - PUNCT bjos-8674720 34 6 recognized recognize VERB bjos-8674720 34 7 gram gram NOUN bjos-8674720 34 8 - - PUNCT bjos-8674720 34 9 negative negative ADJ bjos-8674720 34 10 anaerobic anaerobic ADJ bjos-8674720 34 11 periodontal periodontal ADJ bjos-8674720 34 12 pathogen pathogen NOUN bjos-8674720 34 13 , , PUNCT bjos-8674720 34 14 responsible responsible ADJ bjos-8674720 34 15 for for ADP bjos-8674720 34 16 expressing express VERB bjos-8674720 34 17 class class NOUN bjos-8674720 34 18 ii ii NOUN bjos-8674720 34 19 major major ADJ bjos-8674720 34 20 histocompatibility histocompatibility NOUN bjos-8674720 34 21 complex complex ADJ bjos-8674720 34 22 molecules molecule NOUN bjos-8674720 34 23 , , PUNCT bjos-8674720 34 24 the the DET bjos-8674720 34 25 cell cell NOUN bjos-8674720 34 26 adhesion adhesion NOUN bjos-8674720 34 27 molecules molecule NOUN bjos-8674720 34 28 , , PUNCT bjos-8674720 34 29 intercellular intercellular ADJ bjos-8674720 34 30 adhesion adhesion NOUN bjos-8674720 34 31 molecule-1 molecule-1 PROPN bjos-8674720 34 32 , , PUNCT bjos-8674720 34 33 and and CCONJ bjos-8674720 34 34 cytokines cytokine NOUN bjos-8674720 34 35 and and CCONJ bjos-8674720 34 36 chemokines chemokine NOUN bjos-8674720 34 37 during during ADP bjos-8674720 34 38 inflammation4 inflammation4 PROPN bjos-8674720 34 39 , , PUNCT bjos-8674720 34 40 which which PRON bjos-8674720 34 41 activates activate VERB bjos-8674720 34 42 a a DET bjos-8674720 34 43 host host NOUN bjos-8674720 34 44 response response NOUN bjos-8674720 34 45 that that PRON bjos-8674720 34 46 may may AUX bjos-8674720 34 47 be be AUX bjos-8674720 34 48 associated associate VERB bjos-8674720 34 49 with with ADP bjos-8674720 34 50 the the DET bjos-8674720 34 51 pathogenesis pathogenesis NOUN bjos-8674720 34 52 of of ADP bjos-8674720 34 53 periodontitis7 periodontitis7 PROPN bjos-8674720 34 54 . . PUNCT bjos-8674720 35 1 however however ADV bjos-8674720 35 2 , , PUNCT bjos-8674720 35 3 once once ADV bjos-8674720 35 4     SPACE bjos-8674720 35 5 aa aa NOUN bjos-8674720 35 6     SPACE bjos-8674720 35 7 can can AUX bjos-8674720 35 8 trigger trigger VERB bjos-8674720 35 9 a a DET bjos-8674720 35 10 host host NOUN bjos-8674720 35 11 - - PUNCT bjos-8674720 35 12 inflammatory inflammatory ADJ bjos-8674720 35 13 response response NOUN bjos-8674720 35 14 , , PUNCT bjos-8674720 35 15 its its PRON bjos-8674720 35 16 presence presence NOUN bjos-8674720 35 17 could could AUX bjos-8674720 35 18 affect affect VERB bjos-8674720 35 19 healing healing NOUN bjos-8674720 35 20 processes process NOUN bjos-8674720 35 21 . . PUNCT bjos-8674720 36 1 nevertheless nevertheless ADV bjos-8674720 36 2 , , PUNCT bjos-8674720 36 3 little little ADJ bjos-8674720 36 4 is be AUX bjos-8674720 36 5 known know VERB bjos-8674720 36 6 about about ADP bjos-8674720 36 7 the the DET bjos-8674720 36 8 impact impact NOUN bjos-8674720 36 9 of of ADP bjos-8674720 36 10 pathogens pathogen NOUN bjos-8674720 36 11 on on ADP bjos-8674720 36 12 oral oral ADJ bjos-8674720 36 13 wound wound NOUN bjos-8674720 36 14 healing healing NOUN bjos-8674720 36 15 . . PUNCT bjos-8674720 37 1 in in ADP bjos-8674720 37 2 a a DET bjos-8674720 37 3 study study NOUN bjos-8674720 37 4 investigating investigate VERB bjos-8674720 37 5 palate palate ADJ bjos-8674720 37 6 wounds wound NOUN bjos-8674720 37 7 for for ADP bjos-8674720 37 8 connective connective ADJ bjos-8674720 37 9 tissue tissue NOUN bjos-8674720 37 10 harvesting harvesting NOUN bjos-8674720 37 11 , , PUNCT bjos-8674720 37 12 temporal temporal ADJ bjos-8674720 37 13 changes change NOUN bjos-8674720 37 14 in in ADP bjos-8674720 37 15 the the DET bjos-8674720 37 16 wound wound NOUN bjos-8674720 37 17 area area NOUN bjos-8674720 37 18 during during ADP bjos-8674720 37 19 healing healing NOUN bjos-8674720 37 20 were be AUX bjos-8674720 37 21 demonstrated demonstrate VERB bjos-8674720 37 22 , , PUNCT bjos-8674720 37 23 with with ADP bjos-8674720 37 24 alterations alteration NOUN bjos-8674720 37 25 dependent dependent ADJ bjos-8674720 37 26 on on ADP bjos-8674720 37 27 the the DET bjos-8674720 37 28 surgical surgical ADJ bjos-8674720 37 29 technique technique NOUN bjos-8674720 37 30 employed employ VERB bjos-8674720 37 31 . . PUNCT bjos-8674720 38 1 following follow VERB bjos-8674720 38 2 the the DET bjos-8674720 38 3 rupture rupture NOUN bjos-8674720 38 4 of of ADP bjos-8674720 38 5 the the DET bjos-8674720 38 6 mucosal mucosal NOUN bjos-8674720 38 7 barrier barrier NOUN bjos-8674720 38 8 , , PUNCT bjos-8674720 38 9 oral oral ADJ bjos-8674720 38 10 bacteria bacteria NOUN bjos-8674720 38 11 were be AUX bjos-8674720 38 12 found find VERB bjos-8674720 38 13 to to PART bjos-8674720 38 14 potentially potentially ADV bjos-8674720 38 15 impact impact VERB bjos-8674720 38 16 the the DET bjos-8674720 38 17 healing healing NOUN bjos-8674720 38 18 process process NOUN bjos-8674720 38 19 , , PUNCT bjos-8674720 38 20 as as SCONJ bjos-8674720 38 21 observed observe VERB bjos-8674720 38 22 in in ADP bjos-8674720 38 23 significant significant ADJ bjos-8674720 38 24 effects effect NOUN bjos-8674720 38 25 on on ADP bjos-8674720 38 26 wound wound NOUN bjos-8674720 38 27 re re NOUN bjos-8674720 38 28 - - NOUN bjos-8674720 38 29 epithelialization epithelialization NOUN bjos-8674720 38 30 caused cause VERB bjos-8674720 38 31 by by ADP bjos-8674720 38 32 pg pg PRON bjos-8674720 38 33 and and CCONJ bjos-8674720 38 34 fn fn PROPN bjos-8674720 38 35 , , PUNCT bjos-8674720 38 36 identified identify VERB bjos-8674720 38 37 as as ADP bjos-8674720 38 38 major major ADJ bjos-8674720 38 39 contributors contributor NOUN bjos-8674720 38 40 to to ADP bjos-8674720 38 41 the the DET bjos-8674720 38 42 inhibition inhibition NOUN bjos-8674720 38 43 of of ADP bjos-8674720 38 44 healing8 healing8 NOUN bjos-8674720 38 45 , , PUNCT bjos-8674720 38 46 being be AUX bjos-8674720 38 47 the the DET bjos-8674720 38 48 impact impact NOUN bjos-8674720 38 49 of of ADP bjos-8674720 38 50 aa aa NOUN bjos-8674720 38 51 still still ADV bjos-8674720 38 52 not not PART bjos-8674720 38 53 explored explore VERB bjos-8674720 38 54 . . PUNCT bjos-8674720 39 1 however however ADV bjos-8674720 39 2 , , PUNCT bjos-8674720 39 3 a a DET bjos-8674720 39 4 proliferative proliferative ADJ bjos-8674720 39 5 behavior behavior NOUN bjos-8674720 39 6 of of ADP bjos-8674720 39 7 oral oral ADJ bjos-8674720 39 8 keratinocytes keratinocyte NOUN bjos-8674720 39 9 when when SCONJ bjos-8674720 39 10 stimulated stimulate VERB bjos-8674720 39 11 by by ADP bjos-8674720 39 12     SPACE bjos-8674720 39 13 aa aa PROPN bjos-8674720 39 14 - - PUNCT bjos-8674720 39 15 hsp60 hsp60 PROPN bjos-8674720 39 16 ( ( PUNCT bjos-8674720 39 17 heat heat NOUN bjos-8674720 39 18 shock shock NOUN bjos-8674720 39 19 protein protein NOUN bjos-8674720 39 20 60 60 NUM bjos-8674720 39 21 ) ) PUNCT bjos-8674720 39 22 has have AUX bjos-8674720 39 23 been be AUX bjos-8674720 39 24 reported9 reported9 NOUN bjos-8674720 39 25 . . PUNCT bjos-8674720 40 1 on on ADP bjos-8674720 40 2 the the DET bjos-8674720 40 3 other other ADJ bjos-8674720 40 4 hand hand NOUN bjos-8674720 40 5 , , PUNCT bjos-8674720 40 6 cytolethal cytolethal VERB bjos-8674720 40 7 distending distend VERB bjos-8674720 40 8 toxin toxin NOUN bjos-8674720 40 9 ( ( PUNCT bjos-8674720 40 10 cdt cdt PROPN bjos-8674720 40 11 ) ) PUNCT bjos-8674720 40 12 , , PUNCT bjos-8674720 40 13 a a DET bjos-8674720 40 14 virulence virulence NOUN bjos-8674720 40 15 factor factor NOUN bjos-8674720 40 16 of of ADP bjos-8674720 40 17     SPACE bjos-8674720 40 18 aa aa NOUN bjos-8674720 40 19 , , PUNCT bjos-8674720 40 20 exhibited exhibit VERB bjos-8674720 40 21 the the DET bjos-8674720 40 22 potential potential NOUN bjos-8674720 40 23 for for ADP bjos-8674720 40 24 cell cell NOUN bjos-8674720 40 25 cycle cycle NOUN bjos-8674720 40 26 arrest arrest NOUN bjos-8674720 40 27 , , PUNCT bjos-8674720 40 28 cellular cellular ADJ bjos-8674720 40 29 distension distension NOUN bjos-8674720 40 30 , , PUNCT bjos-8674720 40 31 and and CCONJ bjos-8674720 40 32 death10 death10 NOUN bjos-8674720 40 33 . . PUNCT bjos-8674720 41 1 aa aa PROPN bjos-8674720 41 2     SPACE bjos-8674720 41 3 leukotoxin leukotoxin PROPN bjos-8674720 41 4 may may AUX bjos-8674720 41 5 also also ADV bjos-8674720 41 6 play play VERB bjos-8674720 41 7 a a DET bjos-8674720 41 8 major major ADJ bjos-8674720 41 9 role role NOUN bjos-8674720 41 10 in in ADP bjos-8674720 41 11 destroying destroy VERB bjos-8674720 41 12 the the DET bjos-8674720 41 13 periodontal periodontal ADJ bjos-8674720 41 14 tissues11 tissues11 NOUN bjos-8674720 41 15 . . PUNCT bjos-8674720 42 1 however however ADV bjos-8674720 42 2 , , PUNCT bjos-8674720 42 3 its its PRON bjos-8674720 42 4 impact impact NOUN bjos-8674720 42 5 on on ADP bjos-8674720 42 6 the the DET bjos-8674720 42 7 wound wound NOUN bjos-8674720 42 8 - - PUNCT bjos-8674720 42 9 healing healing NOUN bjos-8674720 42 10 model model NOUN bjos-8674720 42 11 remains remain VERB bjos-8674720 42 12 unknown unknown ADJ bjos-8674720 42 13 . . PUNCT bjos-8674720 43 1 under under ADP bjos-8674720 43 2 healthy healthy ADJ bjos-8674720 43 3 conditions condition NOUN bjos-8674720 43 4 , , PUNCT bjos-8674720 43 5 oral oral ADJ bjos-8674720 43 6 polymicrobial polymicrobial ADJ bjos-8674720 43 7 communities community NOUN bjos-8674720 43 8 still still ADV bjos-8674720 43 9 contain contain VERB bjos-8674720 43 10 periodontal periodontal ADJ bjos-8674720 43 11 pathogens pathogen NOUN bjos-8674720 43 12 , , PUNCT bjos-8674720 43 13 although although SCONJ bjos-8674720 43 14 in in ADP bjos-8674720 43 15 lower low ADJ bjos-8674720 43 16 proportions proportion NOUN bjos-8674720 43 17 . . PUNCT bjos-8674720 44 1 however however ADV bjos-8674720 44 2 , , PUNCT bjos-8674720 44 3 when when SCONJ bjos-8674720 44 4 oral oral ADJ bjos-8674720 44 5 dysbiosis dysbiosis NOUN bjos-8674720 44 6 occurs occur VERB bjos-8674720 44 7 , , PUNCT bjos-8674720 44 8 successive successive ADJ bjos-8674720 44 9 alterations alteration NOUN bjos-8674720 44 10 in in ADP bjos-8674720 44 11 bacterial bacterial ADJ bjos-8674720 44 12 proportions proportion NOUN bjos-8674720 44 13 and and CCONJ bjos-8674720 44 14 changes change NOUN bjos-8674720 44 15 in in ADP bjos-8674720 44 16 the the DET bjos-8674720 44 17 expression expression NOUN bjos-8674720 44 18 profile profile NOUN bjos-8674720 44 19 are be AUX bjos-8674720 44 20 observed observe VERB bjos-8674720 44 21 , , PUNCT bjos-8674720 44 22 rendering render VERB bjos-8674720 44 23 them they PRON bjos-8674720 44 24 more more ADV bjos-8674720 44 25 pathogenic5,6 pathogenic5,6 PROPN bjos-8674720 44 26 . . PUNCT bjos-8674720 45 1 recognizing recognize VERB bjos-8674720 45 2 that that SCONJ bjos-8674720 45 3 epithelial epithelial ADJ bjos-8674720 45 4 cells cell NOUN bjos-8674720 45 5 undergo undergo VERB bjos-8674720 45 6 alterations alteration NOUN bjos-8674720 45 7 when when SCONJ bjos-8674720 45 8 challenged challenge VERB bjos-8674720 45 9 by by ADP bjos-8674720 45 10 periodontal periodontal ADJ bjos-8674720 45 11 pathogens pathogen NOUN bjos-8674720 45 12 , , PUNCT bjos-8674720 45 13 this this DET bjos-8674720 45 14 virulent virulent NOUN bjos-8674720 45 15 profile profile NOUN bjos-8674720 45 16 may may AUX bjos-8674720 45 17 potentially potentially ADV bjos-8674720 45 18 interfere interfere VERB bjos-8674720 45 19 with with ADP bjos-8674720 45 20 and and CCONJ bjos-8674720 45 21 delay delay VERB bjos-8674720 45 22 the the DET bjos-8674720 45 23 healing healing NOUN bjos-8674720 45 24 process8 process8 PROPN bjos-8674720 45 25 , , PUNCT bjos-8674720 45 26 especially especially ADV bjos-8674720 45 27 concerning concern VERB bjos-8674720 45 28 aa aa NOUN bjos-8674720 45 29 , , PUNCT bjos-8674720 45 30 one one NUM bjos-8674720 45 31 of of ADP bjos-8674720 45 32 the the DET bjos-8674720 45 33 bacteria bacteria NOUN bjos-8674720 45 34 most most ADV bjos-8674720 45 35 strongly strongly ADV bjos-8674720 45 36 associated associate VERB bjos-8674720 45 37 with with ADP bjos-8674720 45 38 severe severe ADJ bjos-8674720 45 39 periodontal periodontal ADJ bjos-8674720 45 40 disease disease NOUN bjos-8674720 45 41 . . PUNCT bjos-8674720 46 1 therefore therefore ADV bjos-8674720 46 2 , , PUNCT bjos-8674720 46 3 this this DET bjos-8674720 46 4 study study NOUN bjos-8674720 46 5 investigated investigate VERB bjos-8674720 46 6 how how SCONJ bjos-8674720 46 7 oral oral ADJ bjos-8674720 46 8 keratinocytes keratinocyte NOUN bjos-8674720 46 9 can can AUX bjos-8674720 46 10 modify modify VERB bjos-8674720 46 11 their their PRON bjos-8674720 46 12 healing healing NOUN bjos-8674720 46 13 capacity capacity NOUN bjos-8674720 46 14 when when SCONJ bjos-8674720 46 15 exposed expose VERB bjos-8674720 46 16 to to ADP bjos-8674720 46 17 a a DET bjos-8674720 46 18 protein protein NOUN bjos-8674720 46 19 extract extract NOUN bjos-8674720 46 20 of of ADP bjos-8674720 46 21 aa aa PROPN bjos-8674720 46 22 serotype serotype PROPN bjos-8674720 46 23 jp2 jp2 PROPN bjos-8674720 46 24 in in ADP bjos-8674720 46 25 an an DET bjos-8674720 46 26 in in ADP bjos-8674720 46 27 vitro vitro X bjos-8674720 46 28 wound wound ADJ bjos-8674720 46 29 healing healing NOUN bjos-8674720 46 30 model model NOUN bjos-8674720 46 31 . . PUNCT bjos-8674720 47 1 3 3 NUM bjos-8674720 47 2 mendes mende NOUN bjos-8674720 47 3 et et PROPN bjos-8674720 47 4 al al PROPN bjos-8674720 47 5 . . PROPN bjos-8674720 47 6 braz braz PROPN bjos-8674720 47 7 j j PROPN bjos-8674720 47 8 oral oral PROPN bjos-8674720 47 9 sci sci PROPN bjos-8674720 47 10 . . PUNCT bjos-8674720 48 1 2024;23 2024;23 NUM bjos-8674720 48 2 : : PUNCT bjos-8674720 48 3 e244720 e244720 NOUN bjos-8674720 48 4 materials material NOUN bjos-8674720 48 5 and and CCONJ bjos-8674720 48 6 methods method NOUN bjos-8674720 48 7 : : PUNCT bjos-8674720 48 8 study study NOUN bjos-8674720 48 9 design design NOUN bjos-8674720 48 10 to to PART bjos-8674720 48 11 fulfill fulfill VERB bjos-8674720 48 12 the the DET bjos-8674720 48 13 objectives objective NOUN bjos-8674720 48 14 , , PUNCT bjos-8674720 48 15 a a DET bjos-8674720 48 16 laboratory laboratory NOUN bjos-8674720 48 17 study study NOUN bjos-8674720 48 18 was be AUX bjos-8674720 48 19 designed design VERB bjos-8674720 48 20 involving involve VERB bjos-8674720 48 21 the the DET bjos-8674720 48 22 culture culture NOUN bjos-8674720 48 23 of of ADP bjos-8674720 48 24 lineage lineage NOUN bjos-8674720 48 25 cells cell NOUN bjos-8674720 48 26 . . PUNCT bjos-8674720 49 1 cells cell NOUN bjos-8674720 49 2 were be AUX bjos-8674720 49 3 cultured cultured ADJ bjos-8674720 49 4 , , PUNCT bjos-8674720 49 5 stimulated stimulate VERB bjos-8674720 49 6 , , PUNCT bjos-8674720 49 7 and and CCONJ bjos-8674720 49 8 analyzed analyze VERB bjos-8674720 49 9 as as SCONJ bjos-8674720 49 10 described describe VERB bjos-8674720 49 11 below below ADV bjos-8674720 49 12 . . PUNCT bjos-8674720 50 1 groups group NOUN bjos-8674720 50 2 the the DET bjos-8674720 50 3 following follow VERB bjos-8674720 50 4 groups group NOUN bjos-8674720 50 5 were be AUX bjos-8674720 50 6 defined define VERB bjos-8674720 50 7 : : PUNCT bjos-8674720 50 8 • • NUM bjos-8674720 50 9 ko ko PROPN bjos-8674720 50 10 group group NOUN bjos-8674720 50 11 ( ( PUNCT bjos-8674720 50 12 n=5 n=5 PROPN bjos-8674720 50 13 ): ): PUNCT bjos-8674720 50 14 oral oral ADJ bjos-8674720 50 15 keratinocyte keratinocyte NOUN bjos-8674720 50 16 cells cell NOUN bjos-8674720 50 17 derived derive VERB bjos-8674720 50 18 from from ADP bjos-8674720 50 19 lineage lineage NOUN bjos-8674720 50 20 submitted submit VERB bjos-8674720 50 21 to to ADP bjos-8674720 50 22 the the DET bjos-8674720 50 23 scratching scratching NOUN bjos-8674720 50 24 test test NOUN bjos-8674720 50 25 and and CCONJ bjos-8674720 50 26 cultivated cultivate VERB bjos-8674720 50 27 in in ADP bjos-8674720 50 28 standard standard ADJ bjos-8674720 50 29 medium medium NOUN bjos-8674720 50 30 . . PUNCT bjos-8674720 50 31 • • NUM bjos-8674720 50 32 ko+aa ko+aa NOUN bjos-8674720 50 33     SPACE bjos-8674720 50 34 group group NOUN bjos-8674720 50 35 ( ( PUNCT bjos-8674720 50 36 n=5 n=5 PROPN bjos-8674720 50 37 ): ): PUNCT bjos-8674720 50 38 oral oral ADJ bjos-8674720 50 39 keratinocyte keratinocyte NOUN bjos-8674720 50 40 cells cell NOUN bjos-8674720 50 41 derived derive VERB bjos-8674720 50 42 from from ADP bjos-8674720 50 43 lineage lineage NOUN bjos-8674720 50 44 submitted submit VERB bjos-8674720 50 45 to to ADP bjos-8674720 50 46 the the DET bjos-8674720 50 47 scratching scratching NOUN bjos-8674720 50 48 test test NOUN bjos-8674720 50 49 and and CCONJ bjos-8674720 50 50 cultivated cultivate VERB bjos-8674720 50 51 in in ADP bjos-8674720 50 52 standard standard ADJ bjos-8674720 50 53 medium medium ADJ bjos-8674720 50 54 addition addition NOUN bjos-8674720 50 55 by by ADP bjos-8674720 50 56 total total ADJ bjos-8674720 50 57     SPACE bjos-8674720 50 58 aa aa NOUN bjos-8674720 50 59     SPACE bjos-8674720 50 60 protein protein NOUN bjos-8674720 50 61 extract extract NOUN bjos-8674720 50 62 . . PUNCT bjos-8674720 51 1 aa aa NOUN bjos-8674720 51 2 total total ADJ bjos-8674720 51 3 protein protein NOUN bjos-8674720 51 4 extract extract VERB bjos-8674720 51 5 obtention obtention NOUN bjos-8674720 51 6 aa aa PROPN bjos-8674720 51 7     SPACE bjos-8674720 51 8 total total ADJ bjos-8674720 51 9 protein protein NOUN bjos-8674720 51 10 extract extract NOUN bjos-8674720 51 11 was be AUX bjos-8674720 51 12 obtained obtain VERB bjos-8674720 51 13 as as ADP bjos-8674720 51 14 described describe VERB bjos-8674720 51 15 previously12 previously12 PROPN bjos-8674720 51 16 . . PUNCT bjos-8674720 51 17     SPACE bjos-8674720 52 1 briefly briefly ADV bjos-8674720 52 2 , , PUNCT bjos-8674720 52 3     SPACE bjos-8674720 52 4 aa aa NOUN bjos-8674720 52 5     SPACE bjos-8674720 52 6 strains strain NOUN bjos-8674720 52 7 ( ( PUNCT bjos-8674720 52 8 jp2 jp2 PROPN bjos-8674720 52 9 ) ) PUNCT bjos-8674720 52 10 were be AUX bjos-8674720 52 11 cultivated cultivate VERB bjos-8674720 52 12 on on ADP bjos-8674720 52 13 the the DET bjos-8674720 52 14 surface surface NOUN bjos-8674720 52 15 of of ADP bjos-8674720 52 16 tsbye tsbye NOUN bjos-8674720 52 17 agar agar NOUN bjos-8674720 52 18 ( ( PUNCT bjos-8674720 52 19 trypticase trypticase NOUN bjos-8674720 52 20 soy soy NOUN bjos-8674720 52 21 agar agar NOUN bjos-8674720 52 22 ) ) PUNCT bjos-8674720 52 23 ( ( PUNCT bjos-8674720 52 24 oxoid oxoid PROPN bjos-8674720 52 25 ltd ltd PROPN bjos-8674720 52 26 , , PUNCT bjos-8674720 52 27 basingstoke basingstoke PROPN bjos-8674720 52 28 , , PUNCT bjos-8674720 52 29 hampshire hampshire PROPN bjos-8674720 52 30 , , PUNCT bjos-8674720 52 31 england england PROPN bjos-8674720 52 32 ) ) PUNCT bjos-8674720 52 33 and and CCONJ bjos-8674720 52 34 incubated incubate VERB bjos-8674720 52 35 in in ADP bjos-8674720 52 36 an an DET bjos-8674720 52 37 atmosphere atmosphere NOUN bjos-8674720 52 38 of of ADP bjos-8674720 52 39 10 10 NUM bjos-8674720 52 40 % % NOUN bjos-8674720 52 41 co2 co2 NOUN bjos-8674720 52 42 ( ( PUNCT bjos-8674720 52 43 shel shel PROPN bjos-8674720 52 44 lab lab PROPN bjos-8674720 52 45 , , PUNCT bjos-8674720 52 46 oregon oregon PROPN bjos-8674720 52 47 , , PUNCT bjos-8674720 52 48 usa usa PROPN bjos-8674720 52 49 ) ) PUNCT bjos-8674720 52 50 , , PUNCT bjos-8674720 52 51 at at ADP bjos-8674720 52 52 37 37 NUM bjos-8674720 52 53 ° ° ADP bjos-8674720 52 54 c c NOUN bjos-8674720 52 55 between between ADP bjos-8674720 52 56 2 2 NUM bjos-8674720 52 57 to to PART bjos-8674720 52 58 3 3 NUM bjos-8674720 52 59 days day NOUN bjos-8674720 52 60 . . PUNCT bjos-8674720 53 1 grown grow VERB bjos-8674720 53 2 cells cell NOUN bjos-8674720 53 3 as as ADP bjos-8674720 53 4 planktonic planktonic ADJ bjos-8674720 53 5 cultures culture NOUN bjos-8674720 53 6 were be AUX bjos-8674720 53 7 centrifuged centrifuge VERB bjos-8674720 53 8 ( ( PUNCT bjos-8674720 53 9 15min 15min NUM bjos-8674720 53 10 , , PUNCT bjos-8674720 53 11 2 2 NUM bjos-8674720 53 12 ° ° NOUN bjos-8674720 53 13 c c NOUN bjos-8674720 53 14 , , PUNCT bjos-8674720 53 15 ≈6300 ≈6300 PROPN bjos-8674720 53 16 g g NOUN bjos-8674720 53 17 ) ) PUNCT bjos-8674720 53 18 , , PUNCT bjos-8674720 53 19 and and CCONJ bjos-8674720 53 20 the the DET bjos-8674720 53 21 culture culture NOUN bjos-8674720 53 22 medium medium NOUN bjos-8674720 53 23 was be AUX bjos-8674720 53 24 discarded discard VERB bjos-8674720 53 25 . . PUNCT bjos-8674720 54 1 for for ADP bjos-8674720 54 2 collection collection NOUN bjos-8674720 54 3 and and CCONJ bjos-8674720 54 4 washing washing NOUN bjos-8674720 54 5 , , PUNCT bjos-8674720 54 6 1 1 NUM bjos-8674720 54 7     SPACE bjos-8674720 54 8 ml ml NOUN bjos-8674720 54 9 of of ADP bjos-8674720 54 10 ice ice NOUN bjos-8674720 54 11 - - PUNCT bjos-8674720 54 12 cold cold ADJ bjos-8674720 54 13 saline saline NOUN bjos-8674720 54 14 solution solution NOUN bjos-8674720 54 15 ( ( PUNCT bjos-8674720 54 16 nacl nacl NOUN bjos-8674720 54 17 0.9 0.9 NUM bjos-8674720 54 18 % % NOUN bjos-8674720 54 19 ) ) PUNCT bjos-8674720 54 20 was be AUX bjos-8674720 54 21 added add VERB bjos-8674720 54 22 to to ADP bjos-8674720 54 23 the the DET bjos-8674720 54 24 pellet pellet NOUN bjos-8674720 54 25 , , PUNCT bjos-8674720 54 26 which which PRON bjos-8674720 54 27 was be AUX bjos-8674720 54 28 resuspended resuspend VERB bjos-8674720 54 29 . . PUNCT bjos-8674720 55 1 the the DET bjos-8674720 55 2 cells cell NOUN bjos-8674720 55 3 were be AUX bjos-8674720 55 4 transferred transfer VERB bjos-8674720 55 5 to to PART bjos-8674720 55 6 2ml 2ml VERB bjos-8674720 55 7 microtubes microtube NOUN bjos-8674720 55 8 with with ADP bjos-8674720 55 9 screw screw NOUN bjos-8674720 55 10 caps cap NOUN bjos-8674720 55 11 and and CCONJ bjos-8674720 55 12 an an DET bjos-8674720 55 13 o o NOUN bjos-8674720 55 14 - - NOUN bjos-8674720 55 15 ring ring NOUN bjos-8674720 55 16 ( ( PUNCT bjos-8674720 55 17 axygen axygen PROPN bjos-8674720 55 18 inc inc PROPN bjos-8674720 55 19 . . PROPN bjos-8674720 55 20 , , PUNCT bjos-8674720 55 21 corning corn VERB bjos-8674720 55 22 life life NOUN bjos-8674720 55 23 sciences sciences PROPN bjos-8674720 55 24 , , PUNCT bjos-8674720 55 25 union union NOUN bjos-8674720 55 26 city city NOUN bjos-8674720 55 27 , , PUNCT bjos-8674720 55 28 ca ca PROPN bjos-8674720 55 29 , , PUNCT bjos-8674720 55 30 usa usa PROPN bjos-8674720 55 31 ) ) PUNCT bjos-8674720 55 32 . . PUNCT bjos-8674720 56 1 the the DET bjos-8674720 56 2 tubes tube NOUN bjos-8674720 56 3 were be AUX bjos-8674720 56 4 centrifuged centrifuge VERB bjos-8674720 56 5 ( ( PUNCT bjos-8674720 56 6 4 4 NUM bjos-8674720 56 7     SPACE bjos-8674720 56 8 min min NOUN bjos-8674720 56 9 , , PUNCT bjos-8674720 56 10 2 2 NUM bjos-8674720 56 11 ° ° NOUN bjos-8674720 56 12 c c NOUN bjos-8674720 56 13 , , PUNCT bjos-8674720 56 14 ≈13000 ≈13000 PROPN bjos-8674720 56 15 g g NOUN bjos-8674720 56 16 ) ) PUNCT bjos-8674720 56 17 , , PUNCT bjos-8674720 56 18 and and CCONJ bjos-8674720 56 19 the the DET bjos-8674720 56 20 saline saline ADJ bjos-8674720 56 21 solution solution NOUN bjos-8674720 56 22 was be AUX bjos-8674720 56 23 discarded discard VERB bjos-8674720 56 24 . . PUNCT bjos-8674720 57 1 the the DET bjos-8674720 57 2 cell cell NOUN bjos-8674720 57 3 pellet pellet NOUN bjos-8674720 57 4 was be AUX bjos-8674720 57 5 immediately immediately ADV bjos-8674720 57 6 stored store VERB bjos-8674720 57 7 at at ADP bjos-8674720 57 8 -80 -80 NOUN bjos-8674720 57 9 ° ° NOUN bjos-8674720 57 10 c c NOUN bjos-8674720 57 11 until until ADP bjos-8674720 57 12 protein protein NOUN bjos-8674720 57 13 extraction extraction NOUN bjos-8674720 57 14 . . PUNCT bjos-8674720 58 1 700μl 700μl ADV bjos-8674720 58 2 of of ADP bjos-8674720 58 3 ultra ultra ADJ bjos-8674720 58 4 - - ADJ bjos-8674720 58 5 pure pure ADJ bjos-8674720 58 6 water water NOUN bjos-8674720 58 7 and and CCONJ bjos-8674720 58 8 ≈0.16 ≈0.16 NOUN bjos-8674720 58 9 g g NOUN bjos-8674720 58 10 of of ADP bjos-8674720 58 11 0.1 0.1 NUM bjos-8674720 58 12 mm mm PROPN bjos-8674720 58 13 diameter diameter NOUN bjos-8674720 58 14 zirconia zirconia NOUN bjos-8674720 58 15 beads bead NOUN bjos-8674720 58 16 ( ( PUNCT bjos-8674720 58 17 biospec biospec NOUN bjos-8674720 58 18 products product NOUN bjos-8674720 58 19 , , PUNCT bjos-8674720 58 20 inc inc PROPN bjos-8674720 58 21 . . PROPN bjos-8674720 58 22 , , PUNCT bjos-8674720 58 23 bartlesville bartlesville PROPN bjos-8674720 58 24 , , PUNCT bjos-8674720 58 25 ok ok PROPN bjos-8674720 58 26 , , PUNCT bjos-8674720 58 27 usa usa PROPN bjos-8674720 58 28 ) ) PUNCT bjos-8674720 58 29 were be AUX bjos-8674720 58 30 added add VERB bjos-8674720 58 31 for for ADP bjos-8674720 58 32 total total ADJ bjos-8674720 58 33 protein protein NOUN bjos-8674720 58 34 extraction extraction NOUN bjos-8674720 58 35 . . PUNCT bjos-8674720 59 1 the the DET bjos-8674720 59 2 microtubes microtube NOUN bjos-8674720 59 3 were be AUX bjos-8674720 59 4 placed place VERB bjos-8674720 59 5 in in ADP bjos-8674720 59 6 a a DET bjos-8674720 59 7 mini mini ADJ bjos-8674720 59 8 - - NOUN bjos-8674720 59 9 beadbeater beadbeater NOUN bjos-8674720 59 10 device device NOUN bjos-8674720 59 11 ( ( PUNCT bjos-8674720 59 12 biospec biospec NOUN bjos-8674720 59 13 ) ) PUNCT bjos-8674720 59 14 at at ADP bjos-8674720 59 15 maximum maximum ADJ bjos-8674720 59 16 power power NOUN bjos-8674720 59 17 ( ( PUNCT bjos-8674720 59 18 3 3 NUM bjos-8674720 59 19 cycles cycle NOUN bjos-8674720 59 20 of of ADP bjos-8674720 59 21 60 60 NUM bjos-8674720 59 22 seconds second NOUN bjos-8674720 59 23 with with ADP bjos-8674720 59 24 1 1 NUM bjos-8674720 59 25     SPACE bjos-8674720 59 26 min min NOUN bjos-8674720 59 27 of of ADP bjos-8674720 59 28 rest rest NOUN bjos-8674720 59 29 on on ADP bjos-8674720 59 30 ice ice NOUN bjos-8674720 59 31 ) ) PUNCT bjos-8674720 59 32 . . PUNCT bjos-8674720 60 1 samples sample NOUN bjos-8674720 60 2 were be AUX bjos-8674720 60 3 centrifuged centrifuge VERB bjos-8674720 60 4 twice twice ADV bjos-8674720 60 5 ( ( PUNCT bjos-8674720 60 6 8min 8min NOUN bjos-8674720 60 7 , , PUNCT bjos-8674720 60 8 4 4 NUM bjos-8674720 60 9 ° ° NOUN bjos-8674720 60 10 c c NOUN bjos-8674720 60 11 , , PUNCT bjos-8674720 60 12 ≈13000 ≈13000 PROPN bjos-8674720 60 13 g g NOUN bjos-8674720 60 14 ) ) PUNCT bjos-8674720 60 15 . . PUNCT bjos-8674720 61 1 the the DET bjos-8674720 61 2 bead bead NOUN bjos-8674720 61 3 - - PUNCT bjos-8674720 61 4 free free ADJ bjos-8674720 61 5 supernatant supernatant NOUN bjos-8674720 61 6 was be AUX bjos-8674720 61 7 transferred transfer VERB bjos-8674720 61 8 to to ADP bjos-8674720 61 9 another another DET bjos-8674720 61 10 microtube microtube NOUN bjos-8674720 61 11 , , PUNCT bjos-8674720 61 12 vortexed vortexe VERB bjos-8674720 61 13 ( ( PUNCT bjos-8674720 61 14 10s 10 NOUN bjos-8674720 61 15 ) ) PUNCT bjos-8674720 61 16 , , PUNCT bjos-8674720 61 17 and and CCONJ bjos-8674720 61 18 had have VERB bjos-8674720 61 19 the the DET bjos-8674720 61 20 protein protein NOUN bjos-8674720 61 21 concentration concentration NOUN bjos-8674720 61 22 measured measure VERB bjos-8674720 61 23 using use VERB bjos-8674720 61 24 the the DET bjos-8674720 61 25 bradford bradford NOUN bjos-8674720 61 26 reagent reagent NOUN bjos-8674720 61 27 ( ( PUNCT bjos-8674720 61 28 sigma sigma PROPN bjos-8674720 61 29 ) ) PUNCT bjos-8674720 61 30 . . PUNCT bjos-8674720 62 1 the the DET bjos-8674720 62 2 homogenized homogenized ADJ bjos-8674720 62 3 extract extract NOUN bjos-8674720 62 4 was be AUX bjos-8674720 62 5 divided divide VERB bjos-8674720 62 6 into into ADP bjos-8674720 62 7 single single ADJ bjos-8674720 62 8 - - PUNCT bjos-8674720 62 9 use use NOUN bjos-8674720 62 10 aliquots aliquot NOUN bjos-8674720 62 11 and and CCONJ bjos-8674720 62 12 stored store VERB bjos-8674720 62 13 at at ADP bjos-8674720 62 14 -80 -80 NOUN bjos-8674720 62 15 ° ° NOUN bjos-8674720 62 16 c c NOUN bjos-8674720 62 17 . . PUNCT bjos-8674720 63 1 collections collection NOUN bjos-8674720 63 2 were be AUX bjos-8674720 63 3 performed perform VERB bjos-8674720 63 4 on on ADP bjos-8674720 63 5 at at ADV bjos-8674720 63 6 least least ADV bjos-8674720 63 7 3 3 NUM bjos-8674720 63 8 independent independent ADJ bjos-8674720 63 9 cultures culture NOUN bjos-8674720 63 10 . . PUNCT bjos-8674720 64 1 the the DET bjos-8674720 64 2 quality quality NOUN bjos-8674720 64 3 and and CCONJ bjos-8674720 64 4 integrity integrity NOUN bjos-8674720 64 5 of of ADP bjos-8674720 64 6 the the DET bjos-8674720 64 7 extractions extraction NOUN bjos-8674720 64 8 were be AUX bjos-8674720 64 9 evaluated evaluate VERB bjos-8674720 64 10 by by ADP bjos-8674720 64 11 separating separate VERB bjos-8674720 64 12 8μg 8μg NOUN bjos-8674720 64 13 of of ADP bjos-8674720 64 14 total total ADJ bjos-8674720 64 15 proteins protein NOUN bjos-8674720 64 16 on on ADP bjos-8674720 64 17 8.5 8.5 NUM bjos-8674720 64 18 % % NOUN bjos-8674720 64 19 sds sds NOUN bjos-8674720 64 20 - - PUNCT bjos-8674720 64 21 page page NOUN bjos-8674720 64 22 gels gel NOUN bjos-8674720 64 23 , , PUNCT bjos-8674720 64 24 with with ADP bjos-8674720 64 25 the the DET bjos-8674720 64 26 aid aid NOUN bjos-8674720 64 27 of of ADP bjos-8674720 64 28 the the DET bjos-8674720 64 29 mini mini NOUN bjos-8674720 64 30 - - NOUN bjos-8674720 64 31 protean protean ADJ bjos-8674720 64 32 iii iii NOUN bjos-8674720 64 33 system system NOUN bjos-8674720 64 34 ( ( PUNCT bjos-8674720 64 35 bio bio NOUN bjos-8674720 64 36 - - PUNCT bjos-8674720 64 37 rad rad PROPN bjos-8674720 64 38 , , PUNCT bjos-8674720 64 39 hercules hercule NOUN bjos-8674720 64 40 , , PUNCT bjos-8674720 64 41 ca ca PROPN bjos-8674720 64 42 , , PUNCT bjos-8674720 64 43 usa usa PROPN bjos-8674720 64 44 ) ) PUNCT bjos-8674720 64 45 , , PUNCT bjos-8674720 64 46 in in ADP bjos-8674720 64 47 buffer buffer NOUN bjos-8674720 64 48 run run NOUN bjos-8674720 64 49 ( ( PUNCT bjos-8674720 64 50 tbs tbs NOUN bjos-8674720 64 51 -100 -100 PROPN bjos-8674720 64 52 mm mm PROPN bjos-8674720 64 53 tris tris PROPN bjos-8674720 64 54 - - PUNCT bjos-8674720 64 55 hcl hcl NOUN bjos-8674720 64 56 buffer buffer NOUN bjos-8674720 64 57 , , PUNCT bjos-8674720 64 58 200 200 NUM bjos-8674720 64 59 mm mm NOUN bjos-8674720 64 60 tris tris NOUN bjos-8674720 64 61 , , PUNCT bjos-8674720 64 62 1.37 1.37 NUM bjos-8674720 64 63 m m NOUN bjos-8674720 64 64 nacl nacl NOUN bjos-8674720 64 65 ) ) PUNCT bjos-8674720 64 66 , , PUNCT bjos-8674720 64 67 at at ADP bjos-8674720 64 68 26 26 NUM bjos-8674720 64 69 - - PUNCT bjos-8674720 64 70 36ma 36ma NOUN bjos-8674720 64 71 , , PUNCT bjos-8674720 64 72 for for ADP bjos-8674720 64 73 2h 2h NUM bjos-8674720 64 74 . . PUNCT bjos-8674720 65 1 quality quality NOUN bjos-8674720 65 2 gels gel NOUN bjos-8674720 65 3 were be AUX bjos-8674720 65 4 made make VERB bjos-8674720 65 5 for for ADP bjos-8674720 65 6 all all DET bjos-8674720 65 7 protein protein NOUN bjos-8674720 65 8 extracts extract NOUN bjos-8674720 65 9 and and CCONJ bjos-8674720 65 10 evaluated evaluate VERB bjos-8674720 65 11 by by ADP bjos-8674720 65 12 coomassie coomassie ADJ bjos-8674720 65 13 blue blue NOUN bjos-8674720 65 14 . . PUNCT bjos-8674720 66 1 the the DET bjos-8674720 66 2 presence presence NOUN bjos-8674720 66 3 of of ADP bjos-8674720 66 4 intact intact ADJ bjos-8674720 66 5 bands band NOUN bjos-8674720 66 6 of of ADP bjos-8674720 66 7 different different ADJ bjos-8674720 66 8 sizes size NOUN bjos-8674720 66 9 indicated indicate VERB bjos-8674720 66 10 the the DET bjos-8674720 66 11 integrity integrity NOUN bjos-8674720 66 12 of of ADP bjos-8674720 66 13 the the DET bjos-8674720 66 14 samples sample NOUN bjos-8674720 66 15 . . PUNCT bjos-8674720 67 1 cell cell NOUN bjos-8674720 67 2 viability viability NOUN bjos-8674720 67 3 cell cell NOUN bjos-8674720 67 4 viability viability NOUN bjos-8674720 67 5 was be AUX bjos-8674720 67 6 performed perform VERB bjos-8674720 67 7 by by ADP bjos-8674720 67 8 the the DET bjos-8674720 67 9 mtt mtt NOUN bjos-8674720 67 10 method method NOUN bjos-8674720 67 11 ( ( PUNCT bjos-8674720 67 12 3-(4,5 3-(4,5 PROPN bjos-8674720 67 13 - - PUNCT bjos-8674720 67 14 dimethylthiazol-2 dimethylthiazol-2 NUM bjos-8674720 67 15 - - PUNCT bjos-8674720 67 16 yl)-2,5 yl)-2,5 NOUN bjos-8674720 67 17 - - NOUN bjos-8674720 67 18 diphenyl diphenyl NOUN bjos-8674720 67 19 tetrazolium tetrazolium NOUN bjos-8674720 67 20 bromide bromide NOUN bjos-8674720 67 21 ) ) PUNCT bjos-8674720 67 22 . . PUNCT bjos-8674720 68 1 cells cell NOUN bjos-8674720 68 2 were be AUX bjos-8674720 68 3 plated plate VERB bjos-8674720 68 4 in in ADP bjos-8674720 68 5 96 96 NUM bjos-8674720 68 6 - - PUNCT bjos-8674720 68 7 well well NOUN bjos-8674720 68 8 plates plate NOUN bjos-8674720 68 9 at at ADP bjos-8674720 68 10 a a DET bjos-8674720 68 11 5.0x103 5.0x103 NUM bjos-8674720 68 12 cells/ cells/ NUM bjos-8674720 68 13 well well NOUN bjos-8674720 68 14 concentration concentration NOUN bjos-8674720 68 15 in in ADP bjos-8674720 68 16 standard standard ADJ bjos-8674720 68 17 medium medium NOUN bjos-8674720 68 18 . . PUNCT bjos-8674720 69 1 after after ADP bjos-8674720 69 2 24 24 NUM bjos-8674720 69 3     SPACE bjos-8674720 69 4 hours hour NOUN bjos-8674720 69 5 , , PUNCT bjos-8674720 69 6 the the DET bjos-8674720 69 7 medium medium NOUN bjos-8674720 69 8 was be AUX bjos-8674720 69 9 replaced replace VERB bjos-8674720 69 10 with with ADP bjos-8674720 69 11 medium medium ADJ bjos-8674720 69 12 containing contain VERB bjos-8674720 69 13 0,15 0,15 NOUN bjos-8674720 69 14 , , PUNCT bjos-8674720 69 15 0,30 0,30 NUM bjos-8674720 69 16 , , PUNCT bjos-8674720 69 17 0,45 0,45 PROPN bjos-8674720 69 18 , , PUNCT bjos-8674720 69 19 0,60 0,60 NUM bjos-8674720 69 20 , , PUNCT bjos-8674720 69 21 0,75 0,75 NOUN bjos-8674720 69 22 , , PUNCT bjos-8674720 69 23 and and CCONJ bjos-8674720 69 24 0,90 0,90 NOUN bjos-8674720 69 25     SPACE bjos-8674720 69 26 μg μg NOUN bjos-8674720 69 27 / / SYM bjos-8674720 69 28 ml ml PROPN bjos-8674720 69 29 of of ADP bjos-8674720 69 30 total total ADJ bjos-8674720 69 31     SPACE bjos-8674720 69 32 aa aa NOUN bjos-8674720 69 33     SPACE bjos-8674720 69 34 protein protein NOUN bjos-8674720 69 35 extract extract NOUN bjos-8674720 69 36 . . PUNCT bjos-8674720 70 1 on on ADP bjos-8674720 70 2 days day NOUN bjos-8674720 70 3 3 3 NUM bjos-8674720 70 4 and and CCONJ bjos-8674720 70 5 7 7 NUM bjos-8674720 70 6 , , PUNCT bjos-8674720 70 7 mtt mtt NOUN bjos-8674720 70 8 reagent reagent NOUN bjos-8674720 70 9 was be AUX bjos-8674720 70 10 added add VERB bjos-8674720 70 11 to to ADP bjos-8674720 70 12 each each DET bjos-8674720 70 13 well well ADV bjos-8674720 70 14 and and CCONJ bjos-8674720 70 15 incubated incubate VERB bjos-8674720 70 16 for for ADP bjos-8674720 70 17 4 4 NUM bjos-8674720 70 18 mendes mende NOUN bjos-8674720 70 19 et et PROPN bjos-8674720 70 20 al al PROPN bjos-8674720 70 21 . . PROPN bjos-8674720 70 22 braz braz PROPN bjos-8674720 70 23 j j PROPN bjos-8674720 70 24 oral oral PROPN bjos-8674720 70 25 sci sci PROPN bjos-8674720 70 26 . . PUNCT bjos-8674720 71 1 2024;23 2024;23 NUM bjos-8674720 71 2 : : PUNCT bjos-8674720 71 3 e244720 e244720 NOUN bjos-8674720 71 4 4 4 NUM bjos-8674720 71 5     SPACE bjos-8674720 71 6 hours hour NOUN bjos-8674720 71 7 at at ADP bjos-8674720 71 8 37 37 NUM bjos-8674720 71 9 ° ° ADP bjos-8674720 71 10 c c NOUN bjos-8674720 71 11 in in ADP bjos-8674720 71 12 a a DET bjos-8674720 71 13 humidified humidified ADJ bjos-8674720 71 14 5 5 NUM bjos-8674720 71 15 % % NOUN bjos-8674720 71 16 co2 co2 NOUN bjos-8674720 71 17 incubator incubator NOUN bjos-8674720 71 18 . . PUNCT bjos-8674720 72 1 at at ADP bjos-8674720 72 2 the the DET bjos-8674720 72 3 end end NOUN bjos-8674720 72 4 of of ADP bjos-8674720 72 5 the the DET bjos-8674720 72 6 incubation incubation NOUN bjos-8674720 72 7 period period NOUN bjos-8674720 72 8 , , PUNCT bjos-8674720 72 9 the the DET bjos-8674720 72 10 medium medium NOUN bjos-8674720 72 11 was be AUX bjos-8674720 72 12 removed remove VERB bjos-8674720 72 13 , , PUNCT bjos-8674720 72 14 and and CCONJ bjos-8674720 72 15 the the DET bjos-8674720 72 16 converted converted ADJ bjos-8674720 72 17 dye dye NOUN bjos-8674720 72 18 was be AUX bjos-8674720 72 19 solubilized solubilize VERB bjos-8674720 72 20 with with ADP bjos-8674720 72 21 100 100 NUM bjos-8674720 72 22 % % NOUN bjos-8674720 72 23 ethanol ethanol NOUN bjos-8674720 72 24 . . PUNCT bjos-8674720 73 1 absorbance absorbance NOUN bjos-8674720 73 2 was be AUX bjos-8674720 73 3 measured measure VERB bjos-8674720 73 4 at at ADP bjos-8674720 73 5 a a DET bjos-8674720 73 6 wavelength wavelength NOUN bjos-8674720 73 7 of of ADP bjos-8674720 73 8 570 570 NUM bjos-8674720 73 9     SPACE bjos-8674720 73 10 nm nm NOUN bjos-8674720 73 11 . . PUNCT bjos-8674720 74 1 it it PRON bjos-8674720 74 2 was be AUX bjos-8674720 74 3 decided decide VERB bjos-8674720 74 4 to to PART bjos-8674720 74 5 use use VERB bjos-8674720 74 6 the the DET bjos-8674720 74 7 0.45 0.45 NUM bjos-8674720 74 8     SPACE bjos-8674720 74 9 μg μg NOUN bjos-8674720 74 10 / / SYM bjos-8674720 74 11 ml ml NOUN bjos-8674720 74 12 concentration concentration NOUN bjos-8674720 74 13 because because SCONJ bjos-8674720 74 14 it it PRON bjos-8674720 74 15 was be AUX bjos-8674720 74 16 the the DET bjos-8674720 74 17 lowest low ADJ bjos-8674720 74 18 concentration concentration NOUN bjos-8674720 74 19 that that PRON bjos-8674720 74 20 showed show VERB bjos-8674720 74 21 viability viability NOUN bjos-8674720 74 22 greater great ADJ bjos-8674720 74 23 than than ADP bjos-8674720 74 24 80 80 NUM bjos-8674720 74 25 % % NOUN bjos-8674720 74 26 until until ADP bjos-8674720 74 27 day day NOUN bjos-8674720 74 28 7 7 NUM bjos-8674720 74 29 . . PUNCT bjos-8674720 75 1 the the DET bjos-8674720 75 2 results result NOUN bjos-8674720 75 3 are be AUX bjos-8674720 75 4 shown show VERB bjos-8674720 75 5 in in ADP bjos-8674720 75 6 figure figure NOUN bjos-8674720 75 7 1 1 NUM bjos-8674720 75 8 . . PUNCT bjos-8674720 76 1 cell cell NOUN bjos-8674720 76 2 culture culture NOUN bjos-8674720 76 3 and and CCONJ bjos-8674720 76 4 scratching scratching NOUN bjos-8674720 76 5 test test NOUN bjos-8674720 76 6 this this DET bjos-8674720 76 7 study study NOUN bjos-8674720 76 8 used use VERB bjos-8674720 76 9 lineage lineage NOUN bjos-8674720 76 10 human human ADJ bjos-8674720 76 11 cells cell NOUN bjos-8674720 76 12 ( ( PUNCT bjos-8674720 76 13 hacat hacat PROPN bjos-8674720 76 14 oral oral ADJ bjos-8674720 76 15 keratinocytes keratinocyte NOUN bjos-8674720 76 16 ) ) PUNCT bjos-8674720 76 17 from from ADP bjos-8674720 76 18 periocells periocell NOUN bjos-8674720 76 19 biobank biobank ADJ bjos-8674720 76 20 periodontics periodontic NOUN bjos-8674720 76 21 area area NOUN bjos-8674720 76 22 , , PUNCT bjos-8674720 76 23 fop fop ADJ bjos-8674720 76 24 - - NOUN bjos-8674720 76 25 unicamp unicamp NOUN bjos-8674720 76 26 . . PUNCT bjos-8674720 77 1 the the DET bjos-8674720 77 2 keratinocytes keratinocyte NOUN bjos-8674720 77 3 were be AUX bjos-8674720 77 4 first first ADV bjos-8674720 77 5 grown grow VERB bjos-8674720 77 6 in in ADP bjos-8674720 77 7 a a DET bjos-8674720 77 8 standard standard ADJ bjos-8674720 77 9 culture culture NOUN bjos-8674720 77 10 medium medium NOUN bjos-8674720 77 11 at at ADP bjos-8674720 77 12 37 37 NUM bjos-8674720 77 13 ° ° ADP bjos-8674720 77 14 c c NOUN bjos-8674720 77 15 in in ADP bjos-8674720 77 16 a a DET bjos-8674720 77 17 humidified humidify VERB bjos-8674720 77 18 atmosphere atmosphere NOUN bjos-8674720 77 19 with with ADP bjos-8674720 77 20 5 5 NUM bjos-8674720 77 21 % % NOUN bjos-8674720 77 22 co2 co2 NOUN bjos-8674720 77 23 until until ADP bjos-8674720 77 24 confluence confluence NOUN bjos-8674720 77 25 . . PUNCT bjos-8674720 78 1 then then ADV bjos-8674720 78 2 , , PUNCT bjos-8674720 78 3 the the DET bjos-8674720 78 4 cells cell NOUN bjos-8674720 78 5 were be AUX bjos-8674720 78 6 sown sow VERB bjos-8674720 78 7 in in ADP bjos-8674720 78 8 a a DET bjos-8674720 78 9 concentration concentration NOUN bjos-8674720 78 10 of of ADP bjos-8674720 78 11 1x105 1x105 ADJ bjos-8674720 78 12 cells cell NOUN bjos-8674720 78 13 / / SYM bjos-8674720 78 14 well well ADV bjos-8674720 78 15 on on ADP bjos-8674720 78 16 24 24 NUM bjos-8674720 78 17 well well ADJ bjos-8674720 78 18 plates plate NOUN bjos-8674720 78 19 with with ADP bjos-8674720 78 20 standard standard ADJ bjos-8674720 78 21 culture culture NOUN bjos-8674720 78 22 medium medium NOUN bjos-8674720 78 23 for for ADP bjos-8674720 78 24 24 24 NUM bjos-8674720 78 25     SPACE bjos-8674720 78 26 hours hour NOUN bjos-8674720 78 27 . . PUNCT bjos-8674720 79 1 after after ADP bjos-8674720 79 2 this this DET bjos-8674720 79 3 period period NOUN bjos-8674720 79 4 , , PUNCT bjos-8674720 79 5 the the DET bjos-8674720 79 6 culture culture NOUN bjos-8674720 79 7 medium medium NOUN bjos-8674720 79 8 was be AUX bjos-8674720 79 9 replaced replace VERB bjos-8674720 79 10 by by ADP bjos-8674720 79 11 medium medium NOUN bjos-8674720 79 12 containing contain VERB bjos-8674720 79 13 or or CCONJ bjos-8674720 79 14 not not PART bjos-8674720 79 15 the the DET bjos-8674720 79 16 total total ADJ bjos-8674720 79 17     SPACE bjos-8674720 79 18 aa aa NOUN bjos-8674720 79 19     SPACE bjos-8674720 79 20 extract extract NOUN bjos-8674720 79 21 in in ADP bjos-8674720 79 22 a a DET bjos-8674720 79 23 concentration concentration NOUN bjos-8674720 79 24 of of ADP bjos-8674720 79 25 0.45 0.45 NUM bjos-8674720 79 26     SPACE bjos-8674720 79 27 μg μg NOUN bjos-8674720 79 28 / / SYM bjos-8674720 79 29 ml ml PROPN bjos-8674720 79 30 , , PUNCT bjos-8674720 79 31 and and CCONJ bjos-8674720 79 32 with with ADP bjos-8674720 79 33 the the DET bjos-8674720 79 34 pipette pipette NOUN bjos-8674720 79 35 ’s ’s PART bjos-8674720 79 36 tip tip NOUN bjos-8674720 79 37 , , PUNCT bjos-8674720 79 38 a a DET bjos-8674720 79 39 “ " PUNCT bjos-8674720 79 40 scratch scratch NOUN bjos-8674720 79 41 ” " PUNCT bjos-8674720 79 42 was be AUX bjos-8674720 79 43 made make VERB bjos-8674720 79 44 in in ADP bjos-8674720 79 45 the the DET bjos-8674720 79 46 middle middle NOUN bjos-8674720 79 47 of of ADP bjos-8674720 79 48 each each DET bjos-8674720 79 49 well well NOUN bjos-8674720 79 50 of of ADP bjos-8674720 79 51 the the DET bjos-8674720 79 52 plate plate NOUN bjos-8674720 79 53 . . PUNCT bjos-8674720 80 1 then then ADV bjos-8674720 80 2 , , PUNCT bjos-8674720 80 3 the the DET bjos-8674720 80 4 cells cell NOUN bjos-8674720 80 5 were be AUX bjos-8674720 80 6 kept keep VERB bjos-8674720 80 7 at at ADP bjos-8674720 80 8 37 37 NUM bjos-8674720 80 9 ° ° ADP bjos-8674720 80 10 c c NOUN bjos-8674720 80 11 in in ADP bjos-8674720 80 12 a a DET bjos-8674720 80 13 humidified humidify VERB bjos-8674720 80 14 atmosphere atmosphere NOUN bjos-8674720 80 15 with with ADP bjos-8674720 80 16 5 5 NUM bjos-8674720 80 17 % % NOUN bjos-8674720 80 18 co2 co2 NOUN bjos-8674720 80 19 for for ADP bjos-8674720 80 20 up up ADP bjos-8674720 80 21 to to PART bjos-8674720 80 22 48 48 NUM bjos-8674720 80 23     SPACE bjos-8674720 80 24 hours hour NOUN bjos-8674720 80 25 . . PUNCT bjos-8674720 81 1 only only ADV bjos-8674720 81 2 cells cell NOUN bjos-8674720 81 3 between between ADP bjos-8674720 81 4 the the DET bjos-8674720 81 5 fourth fourth ADJ bjos-8674720 81 6 and and CCONJ bjos-8674720 81 7 sixth sixth ADJ bjos-8674720 81 8 passage passage NOUN bjos-8674720 81 9 were be AUX bjos-8674720 81 10 used use VERB bjos-8674720 81 11 , , PUNCT bjos-8674720 81 12 and and CCONJ bjos-8674720 81 13 the the DET bjos-8674720 81 14 experiment experiment NOUN bjos-8674720 81 15 was be AUX bjos-8674720 81 16 replicated replicate VERB bjos-8674720 81 17 six six NUM bjos-8674720 81 18 times time NOUN bjos-8674720 81 19 . . PUNCT bjos-8674720 82 1 wound wound VERB bjos-8674720 82 2 closure closure NOUN bjos-8674720 82 3 evaluation evaluation NOUN bjos-8674720 82 4 at at ADP bjos-8674720 82 5 time time NOUN bjos-8674720 82 6 0 0 NUM bjos-8674720 82 7 ( ( PUNCT bjos-8674720 82 8 immediately immediately ADV bjos-8674720 82 9 after after ADP bjos-8674720 82 10 the the DET bjos-8674720 82 11 “ " PUNCT bjos-8674720 82 12 scratch scratch NOUN bjos-8674720 82 13 ” " PUNCT bjos-8674720 82 14 ) ) PUNCT bjos-8674720 82 15 , , PUNCT bjos-8674720 82 16 wound wound NOUN bjos-8674720 82 17 areas area NOUN bjos-8674720 82 18 were be AUX bjos-8674720 82 19 visualized visualize VERB bjos-8674720 82 20 and and CCONJ bjos-8674720 82 21 recorded record VERB bjos-8674720 82 22 using use VERB bjos-8674720 82 23 an an DET bjos-8674720 82 24 inverted inverted ADJ bjos-8674720 82 25 microscope microscope NOUN bjos-8674720 82 26 . . PUNCT bjos-8674720 83 1 the the DET bjos-8674720 83 2 images image NOUN bjos-8674720 83 3 were be AUX bjos-8674720 83 4 analyzed analyze VERB bjos-8674720 83 5 , , PUNCT bjos-8674720 83 6 and and CCONJ bjos-8674720 83 7 each each DET bjos-8674720 83 8 image image NOUN bjos-8674720 83 9 had have VERB bjos-8674720 83 10 its its PRON bjos-8674720 83 11 area area NOUN bjos-8674720 83 12 evaluated evaluate VERB bjos-8674720 83 13 by by ADP bjos-8674720 83 14 the the DET bjos-8674720 83 15 imagej imagej ADJ bjos-8674720 83 16 software software NOUN bjos-8674720 83 17 by by ADP bjos-8674720 83 18 a a DET bjos-8674720 83 19 calibrated calibrate VERB bjos-8674720 83 20 single single ADJ bjos-8674720 83 21 examiner examiner NOUN bjos-8674720 83 22 ( ( PUNCT bjos-8674720 83 23 bcm bcm NOUN bjos-8674720 83 24 , , PUNCT bjos-8674720 83 25 intra intra ADJ bjos-8674720 83 26 - - ADJ bjos-8674720 83 27 class class ADJ bjos-8674720 83 28 correlation correlation NOUN bjos-8674720 83 29 coefficient coefficient NOUN bjos-8674720 83 30 ( ( PUNCT bjos-8674720 83 31 icc icc PROPN bjos-8674720 83 32 ) ) PUNCT bjos-8674720 83 33 > > PUNCT bjos-8674720 83 34 85 85 NUM bjos-8674720 83 35 % % NOUN bjos-8674720 83 36 ) ) PUNCT bjos-8674720 83 37 . . PUNCT bjos-8674720 84 1 for for ADP bjos-8674720 84 2 calibration calibration NOUN bjos-8674720 84 3 , , PUNCT bjos-8674720 84 4 the the DET bjos-8674720 84 5 bcm bcm NOUN bjos-8674720 84 6 examiner examiner NOUN bjos-8674720 84 7 had have VERB bjos-8674720 84 8 to to PART bjos-8674720 84 9 perform perform VERB bjos-8674720 84 10 two two NUM bjos-8674720 84 11 measurements measurement NOUN bjos-8674720 84 12 of of ADP bjos-8674720 84 13 the the DET bjos-8674720 84 14 same same ADJ bjos-8674720 84 15 scratch scratch NOUN bjos-8674720 84 16 with with ADP bjos-8674720 84 17 an an DET bjos-8674720 84 18 interval interval NOUN bjos-8674720 84 19 of of ADP bjos-8674720 84 20 24 24 NUM bjos-8674720 84 21     SPACE bjos-8674720 84 22 hours hour NOUN bjos-8674720 84 23 between between ADP bjos-8674720 84 24 them they PRON bjos-8674720 84 25 and and CCONJ bjos-8674720 84 26 obtain obtain VERB bjos-8674720 84 27 an an DET bjos-8674720 84 28 icc icc NOUN bjos-8674720 84 29 greater great ADJ bjos-8674720 84 30 than than ADP bjos-8674720 84 31 85 85 NUM bjos-8674720 84 32 % % NOUN bjos-8674720 84 33 . . PUNCT bjos-8674720 85 1 only only ADV bjos-8674720 85 2 wounds wound NOUN bjos-8674720 85 3 of of ADP bjos-8674720 85 4 similar similar ADJ bjos-8674720 85 5 sizes size NOUN bjos-8674720 85 6 ( ( PUNCT bjos-8674720 85 7 between between ADP bjos-8674720 85 8 900 900 NUM bjos-8674720 85 9 and and CCONJ bjos-8674720 85 10 120 120 NUM bjos-8674720 85 11 % % NOUN bjos-8674720 85 12 100 100 NUM bjos-8674720 85 13 % % NOUN bjos-8674720 85 14 80 80 NUM bjos-8674720 85 15 % % NOUN bjos-8674720 85 16 60 60 NUM bjos-8674720 85 17 % % NOUN bjos-8674720 85 18 40 40 NUM bjos-8674720 85 19 % % NOUN bjos-8674720 85 20 20 20 NUM bjos-8674720 85 21 % % NOUN bjos-8674720 85 22 0 0 NUM bjos-8674720 85 23 % % NOUN bjos-8674720 85 24 day day NOUN bjos-8674720 85 25 01 01 NUM bjos-8674720 85 26 nc nc PROPN bjos-8674720 85 27 0.15 0.15 NUM bjos-8674720 85 28 µg µg NOUN bjos-8674720 85 29 / / SYM bjos-8674720 85 30 ml ml NOUN bjos-8674720 85 31 0.3 0.3 NUM bjos-8674720 85 32 µg µg NOUN bjos-8674720 85 33 / / SYM bjos-8674720 85 34 ml ml NOUN bjos-8674720 85 35 0.45 0.45 NUM bjos-8674720 85 36 µg µg NOUN bjos-8674720 85 37 / / SYM bjos-8674720 85 38 ml ml NOUN bjos-8674720 85 39 0.6 0.6 NUM bjos-8674720 85 40 µg µg NOUN bjos-8674720 85 41 / / SYM bjos-8674720 85 42 ml ml NOUN bjos-8674720 85 43 0.75 0.75 NUM bjos-8674720 85 44 µg µg NOUN bjos-8674720 85 45 / / SYM bjos-8674720 85 46 ml ml NOUN bjos-8674720 85 47 0.9 0.9 NUM bjos-8674720 85 48 µg µg NOUN bjos-8674720 85 49 / / SYM bjos-8674720 85 50 ml ml NOUN bjos-8674720 85 51 day day NOUN bjos-8674720 85 52 03 03 NUM bjos-8674720 85 53 day day NOUN bjos-8674720 85 54 07 07 NUM bjos-8674720 85 55 figure figure NOUN bjos-8674720 85 56 1 1 NUM bjos-8674720 85 57 . . PUNCT bjos-8674720 85 58 effect effect NOUN bjos-8674720 85 59 of of ADP bjos-8674720 85 60 aape aape NOUN bjos-8674720 85 61 on on ADP bjos-8674720 85 62 cell cell NOUN bjos-8674720 85 63 viability viability NOUN bjos-8674720 85 64 . . PUNCT bjos-8674720 86 1 hgfs hgf NOUN bjos-8674720 86 2 were be AUX bjos-8674720 86 3 challenged challenge VERB bjos-8674720 86 4 with with ADP bjos-8674720 86 5 0 0 NUM bjos-8674720 86 6 ( ( PUNCT bjos-8674720 86 7 control control NOUN bjos-8674720 86 8 ) ) PUNCT bjos-8674720 86 9 to to ADP bjos-8674720 86 10 0,9 0,9 NUM bjos-8674720 86 11     SPACE bjos-8674720 86 12 μg μg NOUN bjos-8674720 86 13 / / SYM bjos-8674720 86 14 ml ml PROPN bjos-8674720 86 15 of of ADP bjos-8674720 86 16 aape aape NOUN bjos-8674720 86 17 ( ( PUNCT bjos-8674720 86 18 aggregatibacter aggregatibacter NOUN bjos-8674720 86 19 actinomycetencomitans actinomycetencomitans PROPN bjos-8674720 86 20 protein protein NOUN bjos-8674720 86 21 extract extract NOUN bjos-8674720 86 22 ) ) PUNCT bjos-8674720 86 23 , , PUNCT bjos-8674720 86 24 and and CCONJ bjos-8674720 86 25 the the DET bjos-8674720 86 26 mtt mtt NOUN bjos-8674720 86 27 assay assay VERB bjos-8674720 86 28 for for ADP bjos-8674720 86 29 assessing assess VERB bjos-8674720 86 30 cell cell NOUN bjos-8674720 86 31 metabolism metabolism NOUN bjos-8674720 86 32 and and CCONJ bjos-8674720 86 33 viability viability NOUN bjos-8674720 86 34 was be AUX bjos-8674720 86 35 performed perform VERB bjos-8674720 86 36 on on ADP bjos-8674720 86 37 days day NOUN bjos-8674720 86 38 1 1 NUM bjos-8674720 86 39 , , PUNCT bjos-8674720 86 40 3 3 NUM bjos-8674720 86 41 , , PUNCT bjos-8674720 86 42 and and CCONJ bjos-8674720 86 43 7 7 X bjos-8674720 86 44 . . PUNCT bjos-8674720 87 1 the the DET bjos-8674720 87 2 control control NOUN bjos-8674720 87 3 represents represent VERB bjos-8674720 87 4 100 100 NUM bjos-8674720 87 5 % % NOUN bjos-8674720 87 6 of of ADP bjos-8674720 87 7 viability viability NOUN bjos-8674720 87 8 . . PUNCT bjos-8674720 88 1 5 5 NUM bjos-8674720 88 2 mendes mende NOUN bjos-8674720 88 3 et et PROPN bjos-8674720 88 4 al al PROPN bjos-8674720 88 5 . . PROPN bjos-8674720 88 6 braz braz PROPN bjos-8674720 88 7 j j PROPN bjos-8674720 88 8 oral oral PROPN bjos-8674720 88 9 sci sci PROPN bjos-8674720 88 10 . . PUNCT bjos-8674720 89 1 2024;23 2024;23 NUM bjos-8674720 89 2 : : PUNCT bjos-8674720 89 3 e244720 e244720 NOUN bjos-8674720 89 4 1000 1000 NUM bjos-8674720 89 5     SPACE bjos-8674720 89 6 μm2 μm2 NOUN bjos-8674720 89 7 / / SYM bjos-8674720 89 8 field field NOUN bjos-8674720 89 9 ) ) PUNCT bjos-8674720 89 10 were be AUX bjos-8674720 89 11 included include VERB bjos-8674720 89 12 in in ADP bjos-8674720 89 13 the the DET bjos-8674720 89 14 study study NOUN bjos-8674720 89 15 . . PUNCT bjos-8674720 90 1 the the DET bjos-8674720 90 2 heterogeneous heterogeneous ADJ bjos-8674720 90 3 ones one NOUN bjos-8674720 90 4 were be AUX bjos-8674720 90 5 excluded exclude VERB bjos-8674720 90 6 . . PUNCT bjos-8674720 91 1 the the DET bjos-8674720 91 2 scratch scratch NOUN bjos-8674720 91 3 measurement measurement NOUN bjos-8674720 91 4 was be AUX bjos-8674720 91 5 done do VERB bjos-8674720 91 6 at at ADP bjos-8674720 91 7 0 0 NUM bjos-8674720 91 8 , , PUNCT bjos-8674720 91 9 5 5 NUM bjos-8674720 91 10 , , PUNCT bjos-8674720 91 11 10 10 NUM bjos-8674720 91 12 , , PUNCT bjos-8674720 91 13 24 24 NUM bjos-8674720 91 14 , , PUNCT bjos-8674720 91 15 and and CCONJ bjos-8674720 91 16 48 48 NUM bjos-8674720 91 17     SPACE bjos-8674720 91 18 hours hour NOUN bjos-8674720 91 19 in in ADP bjos-8674720 91 20 the the DET bjos-8674720 91 21 same same ADJ bjos-8674720 91 22 plate plate NOUN bjos-8674720 91 23 position position NOUN bjos-8674720 91 24 and and CCONJ bjos-8674720 91 25 region region NOUN bjos-8674720 91 26 to to PART bjos-8674720 91 27 standardize standardize VERB bjos-8674720 91 28 the the DET bjos-8674720 91 29 wound wound NOUN bjos-8674720 91 30 healing heal VERB bjos-8674720 91 31 analysis analysis NOUN bjos-8674720 91 32 . . PUNCT bjos-8674720 92 1 times time NOUN bjos-8674720 92 2 were be AUX bjos-8674720 92 3 also also ADV bjos-8674720 92 4 standardized standardize VERB bjos-8674720 92 5 according accord VERB bjos-8674720 92 6 to to ADP bjos-8674720 92 7 a a DET bjos-8674720 92 8 previous previous ADJ bjos-8674720 92 9 protocol13 protocol13 NOUN bjos-8674720 92 10 . . PUNCT bjos-8674720 93 1 in in ADP bjos-8674720 93 2 the the DET bjos-8674720 93 3 methodology methodology NOUN bjos-8674720 93 4 used use VERB bjos-8674720 93 5 , , PUNCT bjos-8674720 93 6 wound wound ADJ bjos-8674720 93 7 healing healing NOUN bjos-8674720 93 8 or or CCONJ bjos-8674720 93 9 wound wound NOUN bjos-8674720 93 10 closure closure NOUN bjos-8674720 93 11 refers refer VERB bjos-8674720 93 12 to to ADP bjos-8674720 93 13 the the DET bjos-8674720 93 14 capability capability NOUN bjos-8674720 93 15 of of ADP bjos-8674720 93 16 epithelial epithelial ADJ bjos-8674720 93 17 cells cell NOUN bjos-8674720 93 18 ( ( PUNCT bjos-8674720 93 19 keratinocytes keratinocyte NOUN bjos-8674720 93 20 hacat hacat NUM bjos-8674720 93 21 ) ) PUNCT bjos-8674720 93 22 to to PART bjos-8674720 93 23 migrate migrate VERB bjos-8674720 93 24 to to ADP bjos-8674720 93 25 the the DET bjos-8674720 93 26 scratch scratch NOUN bjos-8674720 93 27 region region NOUN bjos-8674720 93 28 and and CCONJ bjos-8674720 93 29 close close VERB bjos-8674720 93 30 the the DET bjos-8674720 93 31 created create VERB bjos-8674720 93 32 space space NOUN bjos-8674720 93 33 ( ( PUNCT bjos-8674720 93 34 wound wound NOUN bjos-8674720 93 35 ) ) PUNCT bjos-8674720 93 36 . . PUNCT bjos-8674720 94 1 data datum NOUN bjos-8674720 94 2 analysis analysis NOUN bjos-8674720 94 3 repeated repeat VERB bjos-8674720 94 4 measures measure NOUN bjos-8674720 94 5 anova anova PROPN bjos-8674720 94 6 followed follow VERB bjos-8674720 94 7 by by ADP bjos-8674720 94 8 the the DET bjos-8674720 94 9 tukey tukey PROPN bjos-8674720 94 10 test test NOUN bjos-8674720 94 11 was be AUX bjos-8674720 94 12 used use VERB bjos-8674720 94 13 to to PART bjos-8674720 94 14 compare compare VERB bjos-8674720 94 15 groups/ groups/ PROPN bjos-8674720 94 16 times time NOUN bjos-8674720 94 17 of of ADP bjos-8674720 94 18 wound wound ADJ bjos-8674720 94 19 measurements measurement NOUN bjos-8674720 94 20 since since SCONJ bjos-8674720 94 21 it it PRON bjos-8674720 94 22 obtained obtain VERB bjos-8674720 94 23 a a DET bjos-8674720 94 24 normal normal ADJ bjos-8674720 94 25 distribution distribution NOUN bjos-8674720 94 26 in in ADP bjos-8674720 94 27 the the DET bjos-8674720 94 28 shapiro shapiro PROPN bjos-8674720 94 29 - - PUNCT bjos-8674720 94 30 wilk wilk NOUN bjos-8674720 94 31 test test NOUN bjos-8674720 94 32 . . PUNCT bjos-8674720 95 1 a a DET bjos-8674720 95 2 one one NUM bjos-8674720 95 3 - - PUNCT bjos-8674720 95 4 tailed tail VERB bjos-8674720 95 5 student student NOUN bjos-8674720 95 6 ’s ’s PART bjos-8674720 95 7 t t PROPN bjos-8674720 95 8 - - PUNCT bjos-8674720 95 9 test test NOUN bjos-8674720 95 10 was be AUX bjos-8674720 95 11 used use VERB bjos-8674720 95 12 to to PART bjos-8674720 95 13 compare compare VERB bjos-8674720 95 14 groups group NOUN bjos-8674720 95 15 for for ADP bjos-8674720 95 16 the the DET bjos-8674720 95 17 wound wound NOUN bjos-8674720 95 18 closure closure NOUN bjos-8674720 95 19 parameter parameter NOUN bjos-8674720 95 20 . . PUNCT bjos-8674720 96 1 all all DET bjos-8674720 96 2 analyses analysis NOUN bjos-8674720 96 3 considered consider VERB bjos-8674720 96 4 5 5 NUM bjos-8674720 96 5 % % NOUN bjos-8674720 96 6 of of ADP bjos-8674720 96 7 significance significance NOUN bjos-8674720 96 8 and and CCONJ bjos-8674720 96 9 were be AUX bjos-8674720 96 10 done do VERB bjos-8674720 96 11 using use VERB bjos-8674720 96 12 sigmaplot sigmaplot NOUN bjos-8674720 96 13 software software NOUN bjos-8674720 96 14 . . PUNCT bjos-8674720 97 1 results result NOUN bjos-8674720 97 2 as as SCONJ bjos-8674720 97 3 seen see VERB bjos-8674720 97 4 in in ADP bjos-8674720 97 5 figure figure NOUN bjos-8674720 97 6 2 2 NUM bjos-8674720 97 7 , , PUNCT bjos-8674720 97 8 at at ADP bjos-8674720 97 9 time time NOUN bjos-8674720 97 10 0 0 NUM bjos-8674720 97 11 , , PUNCT bjos-8674720 97 12 the the DET bjos-8674720 97 13 wounds wound NOUN bjos-8674720 97 14 in in ADP bjos-8674720 97 15 the the DET bjos-8674720 97 16 control control NOUN bjos-8674720 97 17 group group NOUN bjos-8674720 97 18 ( ( PUNCT bjos-8674720 97 19 nc nc PROPN bjos-8674720 97 20 ) ) PUNCT bjos-8674720 97 21 and and CCONJ bjos-8674720 97 22 the the DET bjos-8674720 97 23 group group NOUN bjos-8674720 97 24 with with ADP bjos-8674720 97 25     SPACE bjos-8674720 97 26 aa aa NOUN bjos-8674720 97 27     SPACE bjos-8674720 97 28 were be AUX bjos-8674720 97 29 similar similar ADJ bjos-8674720 97 30 in in ADP bjos-8674720 97 31 size size NOUN bjos-8674720 97 32 ( ( PUNCT bjos-8674720 97 33 p>0.05 p>0.05 NOUN bjos-8674720 97 34 ) ) PUNCT bjos-8674720 97 35 and and CCONJ bjos-8674720 97 36 were be AUX bjos-8674720 97 37 maintained maintain VERB bjos-8674720 97 38 for for ADP bjos-8674720 97 39 up up ADP bjos-8674720 97 40 to to PART bjos-8674720 97 41 48 48 NUM bjos-8674720 97 42     SPACE bjos-8674720 97 43 hours hour NOUN bjos-8674720 97 44 . . PUNCT bjos-8674720 98 1 however however ADV bjos-8674720 98 2 , , PUNCT bjos-8674720 98 3 when when SCONJ bjos-8674720 98 4 analyzing analyze VERB bjos-8674720 98 5 the the DET bjos-8674720 98 6 timeframe timeframe NOUN bjos-8674720 98 7 and and CCONJ bjos-8674720 98 8 difference difference NOUN bjos-8674720 98 9 between between ADP bjos-8674720 98 10 time time NOUN bjos-8674720 98 11 assessments assessment NOUN bjos-8674720 98 12 , , PUNCT bjos-8674720 98 13 a a DET bjos-8674720 98 14 difference difference NOUN bjos-8674720 98 15 in in ADP bjos-8674720 98 16 how how SCONJ bjos-8674720 98 17 the the DET bjos-8674720 98 18 wound wound NOUN bjos-8674720 98 19 measures measure NOUN bjos-8674720 98 20 behave behave VERB bjos-8674720 98 21 could could AUX bjos-8674720 98 22 indicate indicate VERB bjos-8674720 98 23 a a DET bjos-8674720 98 24 faster fast ADJ bjos-8674720 98 25 closure closure NOUN bjos-8674720 98 26 in in ADP bjos-8674720 98 27 control control NOUN bjos-8674720 98 28 than than ADP bjos-8674720 98 29 in in ADP bjos-8674720 98 30 the the DET bjos-8674720 98 31 ko+aa ko+aa NOUN bjos-8674720 98 32     SPACE bjos-8674720 98 33 group group NOUN bjos-8674720 98 34 . . PUNCT bjos-8674720 99 1 this this DET bjos-8674720 99 2 phenomenon phenomenon NOUN bjos-8674720 99 3 could could AUX bjos-8674720 99 4 be be AUX bjos-8674720 99 5 confirmed confirm VERB bjos-8674720 99 6 when when SCONJ bjos-8674720 99 7 analyzing analyze VERB bjos-8674720 99 8 wound wound NOUN bjos-8674720 99 9 closure closure NOUN bjos-8674720 99 10 ( ( PUNCT bjos-8674720 99 11 figure figure NOUN bjos-8674720 99 12 3 3 NUM bjos-8674720 99 13 ) ) PUNCT bjos-8674720 99 14 . . PUNCT bjos-8674720 100 1 standard standard ADJ bjos-8674720 100 2 measurements measurement NOUN bjos-8674720 100 3 allow allow VERB bjos-8674720 100 4 the the DET bjos-8674720 100 5 determination determination NOUN bjos-8674720 100 6 of of ADP bjos-8674720 100 7 wound wound NOUN bjos-8674720 100 8 closure closure NOUN bjos-8674720 100 9 , , PUNCT bjos-8674720 100 10 considering consider VERB bjos-8674720 100 11 time time NOUN bjos-8674720 100 12 0 0 PUNCT bjos-8674720 100 13 as as ADP bjos-8674720 100 14 a a DET bjos-8674720 100 15 reference reference NOUN bjos-8674720 100 16 . . PUNCT bjos-8674720 101 1 it it PRON bjos-8674720 101 2 is be AUX bjos-8674720 101 3 clear clear ADJ bjos-8674720 101 4 in in ADP bjos-8674720 101 5 figure figure NOUN bjos-8674720 101 6 3 3 NUM bjos-8674720 101 7 that that SCONJ bjos-8674720 101 8     SPACE bjos-8674720 101 9 aa aa NOUN bjos-8674720 101 10     SPACE bjos-8674720 101 11 protein protein NOUN bjos-8674720 101 12 extract extract NOUN bjos-8674720 101 13 reduced reduce VERB bjos-8674720 101 14 wound wound NOUN bjos-8674720 101 15 closure closure NOUN bjos-8674720 101 16 at at ADP bjos-8674720 101 17 10 10 NUM bjos-8674720 101 18 and and CCONJ bjos-8674720 101 19 48 48 NUM bjos-8674720 101 20     SPACE bjos-8674720 101 21 hours hour NOUN bjos-8674720 101 22 ( ( PUNCT bjos-8674720 101 23 p<0.05 p<0.05 NOUN bjos-8674720 101 24 ) ) PUNCT bjos-8674720 101 25 , , PUNCT bjos-8674720 101 26 negatively negatively ADV bjos-8674720 101 27 impacting impact VERB bjos-8674720 101 28 the the DET bjos-8674720 101 29 keratinocyte keratinocyte NOUN bjos-8674720 101 30 ’s ’s PART bjos-8674720 101 31 behavior behavior NOUN bjos-8674720 101 32 . . PUNCT bjos-8674720 102 1 600 600 NUM bjos-8674720 102 2 500 500 NUM bjos-8674720 102 3 a a PRON bjos-8674720 102 4 a a DET bjos-8674720 102 5 b b NOUN bjos-8674720 102 6 b b PROPN bjos-8674720 102 7 c c NOUN bjos-8674720 102 8 d d PROPN bjos-8674720 102 9 c c PROPN bjos-8674720 102 10 b b PROPN bjos-8674720 102 11 a a DET bjos-8674720 102 12 a400 a400 PROPN bjos-8674720 102 13 300 300 NUM bjos-8674720 102 14 200 200 NUM bjos-8674720 102 15 100 100 NUM bjos-8674720 102 16 0 0 NUM bjos-8674720 102 17 0 0 NUM bjos-8674720 102 18 hours hour NOUN bjos-8674720 102 19 5 5 NUM bjos-8674720 102 20 hours hour NOUN bjos-8674720 102 21 ko ko PROPN bjos-8674720 102 22 ko+aa ko+aa PROPN bjos-8674720 102 23 10 10 NUM bjos-8674720 102 24 hours hour NOUN bjos-8674720 102 25 24 24 NUM bjos-8674720 102 26 hours hour NOUN bjos-8674720 102 27 48 48 NUM bjos-8674720 102 28 hours hour NOUN bjos-8674720 102 29 figure figure NOUN bjos-8674720 102 30 2 2 NUM bjos-8674720 102 31 . . PUNCT bjos-8674720 102 32 wound wound NOUN bjos-8674720 102 33 measures measure NOUN bjos-8674720 102 34 ( ( PUNCT bjos-8674720 102 35 μm±sd μm±sd NOUN bjos-8674720 102 36 ) ) PUNCT bjos-8674720 102 37 in in ADP bjos-8674720 102 38 each each DET bjos-8674720 102 39 period period NOUN bjos-8674720 102 40 . . PUNCT bjos-8674720 103 1 different different ADJ bjos-8674720 103 2 letter letter NOUN bjos-8674720 103 3 in in ADP bjos-8674720 103 4 the the DET bjos-8674720 103 5 same same ADJ bjos-8674720 103 6 color color NOUN bjos-8674720 103 7 indicates indicate VERB bjos-8674720 103 8 statistical statistical ADJ bjos-8674720 103 9 differences difference NOUN bjos-8674720 103 10 among among ADP bjos-8674720 103 11 times time NOUN bjos-8674720 103 12 within within ADP bjos-8674720 103 13 the the DET bjos-8674720 103 14 group group NOUN bjos-8674720 103 15 ; ; PUNCT bjos-8674720 103 16 no no DET bjos-8674720 103 17 difference difference NOUN bjos-8674720 103 18 between between ADP bjos-8674720 103 19 groups group NOUN bjos-8674720 103 20 was be AUX bjos-8674720 103 21 seen see VERB bjos-8674720 103 22 ( ( PUNCT bjos-8674720 103 23 two two NUM bjos-8674720 103 24 - - PUNCT bjos-8674720 103 25 way way NOUN bjos-8674720 103 26 anova anova PROPN bjos-8674720 103 27 / / SYM bjos-8674720 103 28 tukey tukey NOUN bjos-8674720 103 29 , , PUNCT bjos-8674720 103 30 p<0.05 p<0.05 NOUN bjos-8674720 103 31 ) ) PUNCT bjos-8674720 103 32 . . PUNCT bjos-8674720 104 1 6 6 NUM bjos-8674720 104 2 mendes mende NOUN bjos-8674720 104 3 et et PROPN bjos-8674720 104 4 al al PROPN bjos-8674720 104 5 . . PROPN bjos-8674720 104 6 braz braz PROPN bjos-8674720 104 7 j j PROPN bjos-8674720 104 8 oral oral PROPN bjos-8674720 104 9 sci sci PROPN bjos-8674720 104 10 . . PUNCT bjos-8674720 105 1 2024;23 2024;23 NUM bjos-8674720 105 2 : : PUNCT bjos-8674720 105 3 e244720 e244720 NOUN bjos-8674720 105 4 discussion discussion NOUN bjos-8674720 105 5 a a DET bjos-8674720 105 6 wide wide ADJ bjos-8674720 105 7 variety variety NOUN bjos-8674720 105 8 of of ADP bjos-8674720 105 9 microorganisms microorganism NOUN bjos-8674720 105 10 inhabit inhabit NOUN bjos-8674720 105 11 the the DET bjos-8674720 105 12 oral oral ADJ bjos-8674720 105 13 cavity cavity NOUN bjos-8674720 105 14 : : PUNCT bjos-8674720 105 15 more more ADJ bjos-8674720 105 16 than than ADP bjos-8674720 105 17 1000 1000 NUM bjos-8674720 105 18 different different ADJ bjos-8674720 105 19 bacterial bacterial ADJ bjos-8674720 105 20 species specie NOUN bjos-8674720 105 21 can can AUX bjos-8674720 105 22 colonize colonize VERB bjos-8674720 105 23 the the DET bjos-8674720 105 24 mouth mouth NOUN bjos-8674720 105 25 , , PUNCT bjos-8674720 105 26 and and CCONJ bjos-8674720 105 27 some some DET bjos-8674720 105 28 studies study NOUN bjos-8674720 105 29 carried carry VERB bjos-8674720 105 30 out out ADP bjos-8674720 105 31 from from ADP bjos-8674720 105 32 the the DET bjos-8674720 105 33 genetic genetic ADJ bjos-8674720 105 34 sequencing sequencing NOUN bjos-8674720 105 35 of of ADP bjos-8674720 105 36 the the DET bjos-8674720 105 37 biofilm biofilm NOUN bjos-8674720 105 38 show show VERB bjos-8674720 105 39 that that SCONJ bjos-8674720 105 40 approximately approximately ADV bjos-8674720 105 41 500 500 NUM bjos-8674720 105 42 species specie NOUN bjos-8674720 105 43 are be AUX bjos-8674720 105 44 similar similar ADJ bjos-8674720 105 45 between between ADP bjos-8674720 105 46 healthy healthy ADJ bjos-8674720 105 47 individuals individual NOUN bjos-8674720 105 48 and and CCONJ bjos-8674720 105 49 those those PRON bjos-8674720 105 50 with with ADP bjos-8674720 105 51 periodontal periodontal ADJ bjos-8674720 105 52 diseases14,15 diseases14,15 NOUN bjos-8674720 105 53 . . PUNCT bjos-8674720 106 1 it it PRON bjos-8674720 106 2 is be AUX bjos-8674720 106 3 acceptable acceptable ADJ bjos-8674720 106 4 and and CCONJ bjos-8674720 106 5 credible credible ADJ bjos-8674720 106 6 that that SCONJ bjos-8674720 106 7 there there PRON bjos-8674720 106 8 is be VERB bjos-8674720 106 9 symbiotic symbiotic ADJ bjos-8674720 106 10 and and CCONJ bjos-8674720 106 11 protective protective ADJ bjos-8674720 106 12 colonization colonization NOUN bjos-8674720 106 13 of of ADP bjos-8674720 106 14 oral oral ADJ bjos-8674720 106 15 tissues tissue NOUN bjos-8674720 106 16 by by ADP bjos-8674720 106 17 commensal commensal NOUN bjos-8674720 106 18 microorganisms microorganism NOUN bjos-8674720 106 19 , , PUNCT bjos-8674720 106 20 which which PRON bjos-8674720 106 21 can can AUX bjos-8674720 106 22 , , PUNCT bjos-8674720 106 23 through through ADP bjos-8674720 106 24 different different ADJ bjos-8674720 106 25 ways way NOUN bjos-8674720 106 26 , , PUNCT bjos-8674720 106 27 act act VERB bjos-8674720 106 28 as as ADP bjos-8674720 106 29 “ " PUNCT bjos-8674720 106 30 guardians guardian NOUN bjos-8674720 106 31 ” " PUNCT bjos-8674720 106 32 of of ADP bjos-8674720 106 33 periodontal periodontal ADJ bjos-8674720 106 34 health health NOUN bjos-8674720 106 35 . . PUNCT bjos-8674720 107 1 at at ADP bjos-8674720 107 2 the the DET bjos-8674720 107 3 same same ADJ bjos-8674720 107 4 time time NOUN bjos-8674720 107 5 , , PUNCT bjos-8674720 107 6 while while SCONJ bjos-8674720 107 7 simultaneously simultaneously ADV bjos-8674720 107 8 inhabiting inhabit VERB bjos-8674720 107 9 the the DET bjos-8674720 107 10 same same ADJ bjos-8674720 107 11 niches niche NOUN bjos-8674720 107 12 , , PUNCT bjos-8674720 107 13 pathobiont pathobiont NOUN bjos-8674720 107 14 microorganisms microorganism NOUN bjos-8674720 107 15 can can AUX bjos-8674720 107 16 , , PUNCT bjos-8674720 107 17 modulated modulate VERB bjos-8674720 107 18 by by ADP bjos-8674720 107 19 local local ADJ bjos-8674720 107 20 and and CCONJ bjos-8674720 107 21 systemic systemic ADJ bjos-8674720 107 22 conditions condition NOUN bjos-8674720 107 23 , , PUNCT bjos-8674720 107 24 participate participate VERB bjos-8674720 107 25 in in ADP bjos-8674720 107 26 the the DET bjos-8674720 107 27 installation installation NOUN bjos-8674720 107 28 of of ADP bjos-8674720 107 29 diseases disease NOUN bjos-8674720 107 30 . . PUNCT bjos-8674720 108 1 oral oral ADJ bjos-8674720 108 2 wounds wound NOUN bjos-8674720 108 3 caused cause VERB bjos-8674720 108 4 by by ADP bjos-8674720 108 5 disease disease NOUN bjos-8674720 108 6 or or CCONJ bjos-8674720 108 7 their their PRON bjos-8674720 108 8 treatment treatment NOUN bjos-8674720 108 9 will will AUX bjos-8674720 108 10 heal heal VERB bjos-8674720 108 11 in in ADP bjos-8674720 108 12 this this DET bjos-8674720 108 13 environment environment NOUN bjos-8674720 108 14 . . PUNCT bjos-8674720 109 1 thus thus ADV bjos-8674720 109 2 , , PUNCT bjos-8674720 109 3 it it PRON bjos-8674720 109 4 is be AUX bjos-8674720 109 5 likely likely ADJ bjos-8674720 109 6 , , PUNCT bjos-8674720 109 7 although although SCONJ bjos-8674720 109 8 still still ADV bjos-8674720 109 9 unexplored unexplore VERB bjos-8674720 109 10 , , PUNCT bjos-8674720 109 11 that that SCONJ bjos-8674720 109 12 bacterial bacterial ADJ bjos-8674720 109 13 agents agent NOUN bjos-8674720 109 14 can can AUX bjos-8674720 109 15 alter alter VERB bjos-8674720 109 16 cellular cellular ADJ bjos-8674720 109 17 events event NOUN bjos-8674720 109 18 during during ADP bjos-8674720 109 19 healing healing NOUN bjos-8674720 109 20 . . PUNCT bjos-8674720 110 1 in in ADP bjos-8674720 110 2 this this DET bjos-8674720 110 3 community community NOUN bjos-8674720 110 4 , , PUNCT bjos-8674720 110 5 pathogens pathogen NOUN bjos-8674720 110 6 that that PRON bjos-8674720 110 7 express express VERB bjos-8674720 110 8 cytotoxic cytotoxic ADJ bjos-8674720 110 9 virulence virulence NOUN bjos-8674720 110 10 factors factor NOUN bjos-8674720 110 11 and and CCONJ bjos-8674720 110 12 , , PUNCT bjos-8674720 110 13 thus thus ADV bjos-8674720 110 14 , , PUNCT bjos-8674720 110 15 modulate modulate VERB bjos-8674720 110 16 the the DET bjos-8674720 110 17 cellular cellular ADJ bjos-8674720 110 18 processes process NOUN bjos-8674720 110 19 involved involve VERB bjos-8674720 110 20 in in ADP bjos-8674720 110 21 healing healing NOUN bjos-8674720 110 22 stand stand VERB bjos-8674720 110 23 out out ADP bjos-8674720 110 24 . . PUNCT bjos-8674720 111 1 the the DET bjos-8674720 111 2 present present ADJ bjos-8674720 111 3 study study NOUN bjos-8674720 111 4 showed show VERB bjos-8674720 111 5 that that SCONJ bjos-8674720 111 6 the the DET bjos-8674720 111 7 presence presence NOUN bjos-8674720 111 8 of of ADP bjos-8674720 111 9 the the DET bjos-8674720 111 10 protein protein NOUN bjos-8674720 111 11 extract extract NOUN bjos-8674720 111 12 of of ADP bjos-8674720 111 13     SPACE bjos-8674720 111 14 aa aa NOUN bjos-8674720 111 15     SPACE bjos-8674720 111 16 could could AUX bjos-8674720 111 17 alter alter VERB bjos-8674720 111 18 wound wound ADJ bjos-8674720 111 19 closure closure NOUN bjos-8674720 111 20 induced induce VERB bjos-8674720 111 21 in in ADP bjos-8674720 111 22 keratinocyte keratinocyte NOUN bjos-8674720 111 23 cultures culture NOUN bjos-8674720 111 24 . . PUNCT bjos-8674720 112 1 the the DET bjos-8674720 112 2 healing healing NOUN bjos-8674720 112 3 process process NOUN bjos-8674720 112 4 of of ADP bjos-8674720 112 5 oral oral ADJ bjos-8674720 112 6 wounds wound NOUN bjos-8674720 112 7 involves involve VERB bjos-8674720 112 8 several several ADJ bjos-8674720 112 9 cellular cellular ADJ bjos-8674720 112 10 profiles profile NOUN bjos-8674720 112 11 . . PUNCT bjos-8674720 113 1 keratinocytes keratinocyte NOUN bjos-8674720 113 2 and and CCONJ bjos-8674720 113 3 fibroblasts fibroblast NOUN bjos-8674720 113 4 are be AUX bjos-8674720 113 5 the the DET bjos-8674720 113 6 main main ADJ bjos-8674720 113 7 constitutive constitutive ADJ bjos-8674720 113 8 cells cell NOUN bjos-8674720 113 9 of of ADP bjos-8674720 113 10 oral oral ADJ bjos-8674720 113 11 tissues tissue NOUN bjos-8674720 113 12 and and CCONJ bjos-8674720 113 13 actively actively ADV bjos-8674720 113 14 participate participate VERB bjos-8674720 113 15 in in ADP bjos-8674720 113 16 this this DET bjos-8674720 113 17 process8 process8 PROPN bjos-8674720 113 18 . . PUNCT bjos-8674720 114 1 macrophages macrophage NOUN bjos-8674720 114 2 , , PUNCT bjos-8674720 114 3 monocytes monocyte NOUN bjos-8674720 114 4 , , PUNCT bjos-8674720 114 5 and and CCONJ bjos-8674720 114 6 neutrophils neutrophil NOUN bjos-8674720 114 7 also also ADV bjos-8674720 114 8 act act VERB bjos-8674720 114 9 in in ADP bjos-8674720 114 10 the the DET bjos-8674720 114 11 wound wound NOUN bjos-8674720 114 12 closure closure NOUN bjos-8674720 114 13 process16 process16 VERB bjos-8674720 114 14 by by ADP bjos-8674720 114 15 removing remove VERB bjos-8674720 114 16 necrotic necrotic ADJ bjos-8674720 114 17 tissue tissue NOUN bjos-8674720 114 18 , , PUNCT bjos-8674720 114 19 cell cell NOUN bjos-8674720 114 20 debris debris NOUN bjos-8674720 114 21 , , PUNCT bjos-8674720 114 22 bacteria bacteria NOUN bjos-8674720 114 23 and and CCONJ bjos-8674720 114 24 curbing curb VERB bjos-8674720 114 25 infection17,18 infection17,18 PROPN bjos-8674720 114 26 . . PUNCT bjos-8674720 115 1 moreover moreover ADV bjos-8674720 115 2 , , PUNCT bjos-8674720 115 3 studies study NOUN bjos-8674720 115 4 confirmed confirm VERB bjos-8674720 115 5 that that SCONJ bjos-8674720 115 6 fibroblasts fibroblast NOUN bjos-8674720 115 7 can can AUX bjos-8674720 115 8 be be AUX bjos-8674720 115 9 affected affect VERB bjos-8674720 115 10 by by ADP bjos-8674720 115 11 different different ADJ bjos-8674720 115 12 stimuli stimulus NOUN bjos-8674720 115 13 , , PUNCT bjos-8674720 115 14 such such ADJ bjos-8674720 115 15 as as ADP bjos-8674720 115 16 hydrogen hydrogen NOUN bjos-8674720 115 17 - - PUNCT bjos-8674720 115 18 rich rich ADJ bjos-8674720 115 19 water16 water16 NOUN bjos-8674720 115 20 , , PUNCT bjos-8674720 115 21 hemp hemp NOUN bjos-8674720 115 22 extract extract NOUN bjos-8674720 115 23 and and CCONJ bjos-8674720 115 24 cannabidiol19 cannabidiol19 NOUN bjos-8674720 115 25 , , PUNCT bjos-8674720 115 26 and and CCONJ bjos-8674720 115 27 l l ADJ bjos-8674720 115 28 - - ADJ bjos-8674720 115 29 ascorbic ascorbic ADJ bjos-8674720 115 30 acid15 acid15 NOUN bjos-8674720 115 31 . . PUNCT bjos-8674720 115 32     SPACE bjos-8674720 116 1 cells cell NOUN bjos-8674720 116 2 involved involve VERB bjos-8674720 116 3 in in ADP bjos-8674720 116 4 the the DET bjos-8674720 116 5 hematopoietic hematopoietic ADJ bjos-8674720 116 6 response response NOUN bjos-8674720 116 7 can can AUX bjos-8674720 116 8 also also ADV bjos-8674720 116 9 alter alter VERB bjos-8674720 116 10 their their PRON bjos-8674720 116 11 response response NOUN bjos-8674720 116 12 when when SCONJ bjos-8674720 116 13 in in ADP bjos-8674720 116 14 contact contact NOUN bjos-8674720 116 15 with with ADP bjos-8674720 116 16 oral oral ADJ bjos-8674720 116 17 pathogens pathogen NOUN bjos-8674720 116 18 , , PUNCT bjos-8674720 116 19 modifying modify VERB bjos-8674720 116 20 cytokine cytokine ADJ bjos-8674720 116 21 production production NOUN bjos-8674720 116 22 or or CCONJ bjos-8674720 116 23 even even ADV bjos-8674720 116 24 inducing induce VERB bjos-8674720 116 25 a a DET bjos-8674720 116 26 disease disease NOUN bjos-8674720 116 27 - - PUNCT bjos-8674720 116 28 associated associate VERB bjos-8674720 116 29 pro pro ADJ bjos-8674720 116 30 - - ADJ bjos-8674720 116 31 inflammatory inflammatory ADJ bjos-8674720 116 32 response16,17 response16,17 NOUN bjos-8674720 116 33 . . PUNCT bjos-8674720 117 1 figure figure NOUN bjos-8674720 117 2 3 3 NUM bjos-8674720 117 3 . . PUNCT bjos-8674720 118 1 wound wound NOUN bjos-8674720 118 2 closure closure NOUN bjos-8674720 118 3 ( ( PUNCT bjos-8674720 118 4 μm±sd μm±sd NOUN bjos-8674720 118 5 ) ) PUNCT bjos-8674720 118 6 in in ADP bjos-8674720 118 7 each each DET bjos-8674720 118 8 period period NOUN bjos-8674720 118 9 . . PUNCT bjos-8674720 119 1 * * PUNCT bjos-8674720 119 2 indicates indicate VERB bjos-8674720 119 3 a a DET bjos-8674720 119 4 statistical statistical ADJ bjos-8674720 119 5 difference difference NOUN bjos-8674720 119 6 between between ADP bjos-8674720 119 7 groups group NOUN bjos-8674720 119 8 ( ( PUNCT bjos-8674720 119 9 student student NOUN bjos-8674720 119 10 ’s ’s PART bjos-8674720 119 11 t t PROPN bjos-8674720 119 12 - - PUNCT bjos-8674720 119 13 test test NOUN bjos-8674720 119 14 , , PUNCT bjos-8674720 119 15 p<0.05 p<0.05 NOUN bjos-8674720 119 16 ) ) PUNCT bjos-8674720 119 17 450 450 NUM bjos-8674720 119 18 400 400 NUM bjos-8674720 119 19 350 350 NUM bjos-8674720 119 20 300 300 NUM bjos-8674720 119 21 250 250 NUM bjos-8674720 119 22 200 200 NUM bjos-8674720 119 23 150 150 NUM bjos-8674720 119 24 100 100 NUM bjos-8674720 119 25 50 50 NUM bjos-8674720 119 26 0 0 NUM bjos-8674720 119 27 5 5 NUM bjos-8674720 119 28 hours hour NOUN bjos-8674720 119 29 ko ko PROPN bjos-8674720 119 30 ko+aa ko+aa PROPN bjos-8674720 119 31 10 10 NUM bjos-8674720 119 32 hours hour NOUN bjos-8674720 119 33 24 24 NUM bjos-8674720 119 34 hours hour NOUN bjos-8674720 119 35 * * PUNCT bjos-8674720 120 1 * * PUNCT bjos-8674720 120 2 48 48 NUM bjos-8674720 120 3 hours hour NOUN bjos-8674720 120 4 7 7 NUM bjos-8674720 120 5 mendes mende NOUN bjos-8674720 120 6 et et PROPN bjos-8674720 120 7 al al PROPN bjos-8674720 120 8 . . PROPN bjos-8674720 120 9 braz braz PROPN bjos-8674720 120 10 j j PROPN bjos-8674720 120 11 oral oral PROPN bjos-8674720 120 12 sci sci PROPN bjos-8674720 120 13 . . PUNCT bjos-8674720 121 1 2024;23 2024;23 NUM bjos-8674720 121 2 : : PUNCT bjos-8674720 121 3 e244720 e244720 NOUN bjos-8674720 121 4 studies study NOUN bjos-8674720 121 5     SPACE bjos-8674720 121 6 in in ADP bjos-8674720 121 7 vitro vitro VERB bjos-8674720 121 8     SPACE bjos-8674720 121 9 assessing assess VERB bjos-8674720 121 10 the the DET bjos-8674720 121 11 role role NOUN bjos-8674720 121 12 of of ADP bjos-8674720 121 13 fibroblasts fibroblast NOUN bjos-8674720 121 14 in in ADP bjos-8674720 121 15 wound wound NOUN bjos-8674720 121 16 closure16,18,19 closure16,18,19 NOUN bjos-8674720 121 17 observed observe VERB bjos-8674720 121 18 that that SCONJ bjos-8674720 121 19 they they PRON bjos-8674720 121 20 present present VERB bjos-8674720 121 21 a a DET bjos-8674720 121 22 high high ADJ bjos-8674720 121 23 migration migration NOUN bjos-8674720 121 24 speed speed NOUN bjos-8674720 121 25 and and CCONJ bjos-8674720 121 26 proliferation proliferation NOUN bjos-8674720 121 27 during during ADP bjos-8674720 121 28 healing healing NOUN bjos-8674720 121 29 . . PUNCT bjos-8674720 122 1 however however ADV bjos-8674720 122 2 , , PUNCT bjos-8674720 122 3 ko ko PROPN bjos-8674720 122 4 is be AUX bjos-8674720 122 5 even even ADV bjos-8674720 122 6 more more ADV bjos-8674720 122 7 essential essential ADJ bjos-8674720 122 8 in in ADP bjos-8674720 122 9 wound wound NOUN bjos-8674720 122 10 healing healing NOUN bjos-8674720 122 11 once once SCONJ bjos-8674720 122 12 it it PRON bjos-8674720 122 13 is be AUX bjos-8674720 122 14 responsible responsible ADJ bjos-8674720 122 15 for for ADP bjos-8674720 122 16 wound wound NOUN bjos-8674720 122 17 re re NOUN bjos-8674720 122 18 - - NOUN bjos-8674720 122 19 epithelialization18 epithelialization18 NOUN bjos-8674720 122 20 and and CCONJ bjos-8674720 122 21 for for ADP bjos-8674720 122 22 protecting protect VERB bjos-8674720 122 23 the the DET bjos-8674720 122 24 internal internal ADJ bjos-8674720 122 25 face face NOUN bjos-8674720 122 26 of of ADP bjos-8674720 122 27 the the DET bjos-8674720 122 28 wound wound NOUN bjos-8674720 122 29 from from ADP bjos-8674720 122 30 external external ADJ bjos-8674720 122 31 stimulus stimulus NOUN bjos-8674720 122 32 while while SCONJ bjos-8674720 122 33 the the DET bjos-8674720 122 34 connective connective ADJ bjos-8674720 122 35 tissue tissue NOUN bjos-8674720 122 36 heals heal VERB bjos-8674720 122 37 . . PUNCT bjos-8674720 123 1 it it PRON bjos-8674720 123 2 has have AUX bjos-8674720 123 3 been be AUX bjos-8674720 123 4 reported report VERB bjos-8674720 123 5 that that SCONJ bjos-8674720 123 6 keratinocytes keratinocyte NOUN bjos-8674720 123 7 can can AUX bjos-8674720 123 8 re re VERB bjos-8674720 123 9 - - VERB bjos-8674720 123 10 epithelialize epithelialize VERB bjos-8674720 123 11 the the DET bjos-8674720 123 12 wound wound NOUN bjos-8674720 123 13 area area NOUN bjos-8674720 123 14 very very ADV bjos-8674720 123 15 quickly quickly ADV bjos-8674720 123 16 , , PUNCT bjos-8674720 123 17 usually usually ADV bjos-8674720 123 18 closing close VERB bjos-8674720 123 19 a a DET bjos-8674720 123 20 wound wound NOUN bjos-8674720 123 21 in in ADP bjos-8674720 123 22 approximately approximately ADV bjos-8674720 123 23 18 18 NUM bjos-8674720 123 24     SPACE bjos-8674720 123 25 hours hour NOUN bjos-8674720 123 26 . . PUNCT bjos-8674720 124 1 this this DET bjos-8674720 124 2     SPACE bjos-8674720 124 3 re re NOUN bjos-8674720 124 4 - - NOUN bjos-8674720 124 5 epithelization epithelization NOUN bjos-8674720 124 6 phenomenon phenomenon NOUN bjos-8674720 124 7 enrolls enroll VERB bjos-8674720 124 8 keratinocytes keratinocyte NOUN bjos-8674720 124 9 moving move VERB bjos-8674720 124 10 into into ADP bjos-8674720 124 11 the the DET bjos-8674720 124 12 defect defect ADJ bjos-8674720 124 13 24 24 NUM bjos-8674720 124 14     SPACE bjos-8674720 124 15 hours hour NOUN bjos-8674720 124 16 after after ADP bjos-8674720 124 17 the the DET bjos-8674720 124 18 injury20 injury20 NOUN bjos-8674720 124 19 . . PUNCT bjos-8674720 125 1 during during ADP bjos-8674720 125 2 this this DET bjos-8674720 125 3 migration migration NOUN bjos-8674720 125 4 , , PUNCT bjos-8674720 125 5 keratinocytes keratinocyte NOUN bjos-8674720 125 6 from from ADP bjos-8674720 125 7 wound wound NOUN bjos-8674720 125 8 borders border NOUN bjos-8674720 125 9 have have VERB bjos-8674720 125 10 their their PRON bjos-8674720 125 11 hemidesmosome hemidesmosome NOUN bjos-8674720 125 12 connections connection NOUN bjos-8674720 125 13 dissolved dissolve VERB bjos-8674720 125 14 from from ADP bjos-8674720 125 15 residual residual ADJ bjos-8674720 125 16 epithelial epithelial ADJ bjos-8674720 125 17 structures structure NOUN bjos-8674720 125 18 . . PUNCT bjos-8674720 126 1 they they PRON bjos-8674720 126 2 detach detach VERB bjos-8674720 126 3 from from ADP bjos-8674720 126 4 the the DET bjos-8674720 126 5 base base NOUN bjos-8674720 126 6 of of ADP bjos-8674720 126 7 the the DET bjos-8674720 126 8 membrane membrane NOUN bjos-8674720 126 9 and and CCONJ bjos-8674720 126 10 move move VERB bjos-8674720 126 11 quickly quickly ADV bjos-8674720 126 12 across across ADP bjos-8674720 126 13 the the DET bjos-8674720 126 14 wound wound NOUN bjos-8674720 126 15 defect defect NOUN bjos-8674720 126 16 . . PUNCT bjos-8674720 127 1 later later ADV bjos-8674720 127 2 , , PUNCT bjos-8674720 127 3 as as ADP bjos-8674720 127 4 the the DET bjos-8674720 127 5 re re NOUN bjos-8674720 127 6 - - NOUN bjos-8674720 127 7 epithelialization epithelialization NOUN bjos-8674720 127 8 proceeds proceed NOUN bjos-8674720 127 9 , , PUNCT bjos-8674720 127 10 the the DET bjos-8674720 127 11 keratinocytes keratinocyte NOUN bjos-8674720 127 12 proliferate proliferate VERB bjos-8674720 127 13 to to ADP bjos-8674720 127 14 the the DET bjos-8674720 127 15 wound wound NOUN bjos-8674720 127 16 area area NOUN bjos-8674720 127 17 , , PUNCT bjos-8674720 127 18 supporting support VERB bjos-8674720 127 19 the the DET bjos-8674720 127 20 advancing advance VERB bjos-8674720 127 21 epithelial epithelial ADJ bjos-8674720 127 22 edge edge NOUN bjos-8674720 127 23 . . PUNCT bjos-8674720 128 1 however however ADV bjos-8674720 128 2 , , PUNCT bjos-8674720 128 3 which which PRON bjos-8674720 128 4 cells cell NOUN bjos-8674720 128 5 are be AUX bjos-8674720 128 6 the the DET bjos-8674720 128 7 first first ADJ bjos-8674720 128 8 to to PART bjos-8674720 128 9 arrive arrive VERB bjos-8674720 128 10 in in ADP bjos-8674720 128 11 the the DET bjos-8674720 128 12 wound21 wound21 NOUN bjos-8674720 128 13 is be AUX bjos-8674720 128 14 still still ADV bjos-8674720 128 15 unclear unclear ADJ bjos-8674720 128 16 . . PUNCT bjos-8674720 129 1 meanwhile meanwhile ADV bjos-8674720 129 2 , , PUNCT bjos-8674720 129 3 as as SCONJ bjos-8674720 129 4 previously previously ADV bjos-8674720 129 5 discussed discuss VERB bjos-8674720 129 6 , , PUNCT bjos-8674720 129 7 in in ADP bjos-8674720 129 8 oral oral ADJ bjos-8674720 129 9 wounds wound NOUN bjos-8674720 129 10 , , PUNCT bjos-8674720 129 11 the the DET bjos-8674720 129 12 healing healing NOUN bjos-8674720 129 13 process process NOUN bjos-8674720 129 14 will will AUX bjos-8674720 129 15 occur occur VERB bjos-8674720 129 16 under under ADP bjos-8674720 129 17 an an DET bjos-8674720 129 18 infective infective ADJ bjos-8674720 129 19 environment environment NOUN bjos-8674720 129 20 , , PUNCT bjos-8674720 129 21 and and CCONJ bjos-8674720 129 22 the the DET bjos-8674720 129 23 type type NOUN bjos-8674720 129 24 of of ADP bjos-8674720 129 25 bacteria bacteria NOUN bjos-8674720 129 26 could could AUX bjos-8674720 129 27 alter alter VERB bjos-8674720 129 28 cell cell NOUN bjos-8674720 129 29 behavior behavior NOUN bjos-8674720 129 30 – – PUNCT bjos-8674720 129 31 positive positive ADJ bjos-8674720 129 32 or or CCONJ bjos-8674720 129 33 negative negative ADJ bjos-8674720 129 34 . . PUNCT bjos-8674720 130 1 some some DET bjos-8674720 130 2 probiotic probiotic ADJ bjos-8674720 130 3 species specie NOUN bjos-8674720 130 4 , , PUNCT bjos-8674720 130 5 such such ADJ bjos-8674720 130 6 as as ADP bjos-8674720 130 7     SPACE bjos-8674720 130 8 lactobacillus lactobacillus NOUN bjos-8674720 130 9 rhamnosus rhamnosus PROPN bjos-8674720 130 10 gg gg PROPN bjos-8674720 130 11 , , PUNCT bjos-8674720 130 12 could could AUX bjos-8674720 130 13 improve improve VERB bjos-8674720 130 14 wound wound ADJ bjos-8674720 130 15 healing healing NOUN bjos-8674720 130 16 , , PUNCT bjos-8674720 130 17 acting act VERB bjos-8674720 130 18 as as ADP bjos-8674720 130 19 a a DET bjos-8674720 130 20 healing healing NOUN bjos-8674720 130 21 accelerator20 accelerator20 NOUN bjos-8674720 130 22 . . PUNCT bjos-8674720 131 1 these these DET bjos-8674720 131 2 results result NOUN bjos-8674720 131 3 corroborate corroborate VERB bjos-8674720 131 4 subsequent subsequent ADJ bjos-8674720 131 5 findings13 findings13 NOUN bjos-8674720 131 6 , , PUNCT bjos-8674720 131 7 whose whose DET bjos-8674720 131 8 two two NUM bjos-8674720 131 9 types type NOUN bjos-8674720 131 10 of of ADP bjos-8674720 131 11 probiotics probiotic NOUN bjos-8674720 131 12 ( ( PUNCT bjos-8674720 131 13 lactobacillus lactobacillus NOUN bjos-8674720 131 14 casei casei VERB bjos-8674720 131 15     SPACE bjos-8674720 131 16 324 324 NUM bjos-8674720 131 17 and and CCONJ bjos-8674720 131 18     SPACE bjos-8674720 131 19 bifidobacterium bifidobacterium NOUN bjos-8674720 131 20 pseudolongum pseudolongum NOUN bjos-8674720 131 21 ) ) PUNCT bjos-8674720 131 22 accelerated accelerate VERB bjos-8674720 131 23 the the DET bjos-8674720 131 24 re re NOUN bjos-8674720 131 25 - - NOUN bjos-8674720 131 26 epithelialization epithelialization NOUN bjos-8674720 131 27 of of ADP bjos-8674720 131 28 gingival gingival ADJ bjos-8674720 131 29 epithelial epithelial ADJ bjos-8674720 131 30 cells cell NOUN bjos-8674720 131 31 compared compare VERB bjos-8674720 131 32 to to ADP bjos-8674720 131 33 the the DET bjos-8674720 131 34 control control NOUN bjos-8674720 131 35 group group NOUN bjos-8674720 131 36 . . PUNCT bjos-8674720 132 1 however however ADV bjos-8674720 132 2 , , PUNCT bjos-8674720 132 3 pathobionts pathobiont NOUN bjos-8674720 132 4 could could AUX bjos-8674720 132 5 negatively negatively ADV bjos-8674720 132 6 alter alter VERB bjos-8674720 132 7 this this DET bjos-8674720 132 8 process process NOUN bjos-8674720 132 9 . . PUNCT bjos-8674720 133 1 studies study NOUN bjos-8674720 133 2 showed show VERB bjos-8674720 133 3 that that SCONJ bjos-8674720 133 4 when when SCONJ bjos-8674720 133 5 these these DET bjos-8674720 133 6 cells cell NOUN bjos-8674720 133 7 are be AUX bjos-8674720 133 8 exposed expose VERB bjos-8674720 133 9 to to ADP bjos-8674720 133 10 pg pg VERB bjos-8674720 133 11 , , PUNCT bjos-8674720 133 12 their their PRON bjos-8674720 133 13 proliferation proliferation NOUN bjos-8674720 133 14 capacity capacity NOUN bjos-8674720 133 15 drops drop VERB bjos-8674720 133 16 considerably considerably ADV bjos-8674720 133 17 . . PUNCT bjos-8674720 134 1 pg pg PROPN bjos-8674720 134 2 can can AUX bjos-8674720 134 3 inhibit inhibit VERB bjos-8674720 134 4 tissue tissue NOUN bjos-8674720 134 5 growth8,18 growth8,18 NOUN bjos-8674720 134 6 and and CCONJ bjos-8674720 134 7 display display VERB bjos-8674720 134 8 a a DET bjos-8674720 134 9 destructive destructive ADJ bjos-8674720 134 10 effect13 effect13 NOUN bjos-8674720 134 11 . . PUNCT bjos-8674720 135 1 when when SCONJ bjos-8674720 135 2 oba-9 oba-9 ADV bjos-8674720 135 3 ( ( PUNCT bjos-8674720 135 4 immortalized immortalize VERB bjos-8674720 135 5 human human ADJ bjos-8674720 135 6 gingival gingival NOUN bjos-8674720 135 7 epithelial epithelial ADJ bjos-8674720 135 8 cells cell NOUN bjos-8674720 135 9 ) ) PUNCT bjos-8674720 135 10 are be AUX bjos-8674720 135 11 infected infect VERB bjos-8674720 135 12 with with ADP bjos-8674720 135 13 pg pg PROPN bjos-8674720 135 14 w83 w83 PROPN bjos-8674720 135 15 , , PUNCT bjos-8674720 135 16 the the DET bjos-8674720 135 17 wound wound NOUN bjos-8674720 135 18 becomes become VERB bjos-8674720 135 19 larger large ADJ bjos-8674720 135 20 instead instead ADV bjos-8674720 135 21 of of ADP bjos-8674720 135 22 lessening lessen VERB bjos-8674720 135 23 by by ADP bjos-8674720 135 24 reducing reduce VERB bjos-8674720 135 25 the the DET bjos-8674720 135 26 cell cell NOUN bjos-8674720 135 27 viability viability NOUN bjos-8674720 135 28 compared compare VERB bjos-8674720 135 29 to to ADP bjos-8674720 135 30 the the DET bjos-8674720 135 31 control control NOUN bjos-8674720 135 32 group13 group13 NOUN bjos-8674720 135 33 . . PUNCT bjos-8674720 136 1 besides besides SCONJ bjos-8674720 136 2 , , PUNCT bjos-8674720 136 3 keratinocytes keratinocyte NOUN bjos-8674720 136 4 can can AUX bjos-8674720 136 5 present present VERB bjos-8674720 136 6 healing healing NOUN bjos-8674720 136 7 delayed delay VERB bjos-8674720 136 8 by by ADP bjos-8674720 136 9 the the DET bjos-8674720 136 10 influence influence NOUN bjos-8674720 136 11 of of ADP bjos-8674720 136 12 two two NUM bjos-8674720 136 13 oral oral ADJ bjos-8674720 136 14 pathogens pathogen NOUN bjos-8674720 136 15 ( ( PUNCT bjos-8674720 136 16 pg pg NOUN bjos-8674720 136 17     SPACE bjos-8674720 136 18 and and CCONJ bjos-8674720 136 19     SPACE bjos-8674720 136 20 fn fn NOUN bjos-8674720 136 21 ) ) PUNCT bjos-8674720 136 22 , , PUNCT bjos-8674720 136 23 and and CCONJ bjos-8674720 136 24 it it PRON bjos-8674720 136 25 was be AUX bjos-8674720 136 26 noticed notice VERB bjos-8674720 136 27 that that SCONJ bjos-8674720 136 28 the the DET bjos-8674720 136 29 long long ADJ bjos-8674720 136 30 - - PUNCT bjos-8674720 136 31 term term NOUN bjos-8674720 136 32 effect effect NOUN bjos-8674720 136 33 ( ( PUNCT bjos-8674720 136 34 especially especially ADV bjos-8674720 136 35 in in ADP bjos-8674720 136 36 days day NOUN bjos-8674720 136 37 4 4 NUM bjos-8674720 136 38 and and CCONJ bjos-8674720 136 39 8) 8) NUM bjos-8674720 136 40 caused cause VERB bjos-8674720 136 41 a a DET bjos-8674720 136 42 major major ADJ bjos-8674720 136 43 delay delay NOUN bjos-8674720 136 44 in in ADP bjos-8674720 136 45 the the DET bjos-8674720 136 46 healing healing NOUN bjos-8674720 136 47 in in ADP bjos-8674720 136 48 at at ADV bjos-8674720 136 49 least least ADJ bjos-8674720 136 50 70%8 70%8 NUM bjos-8674720 136 51 . . PUNCT bjos-8674720 137 1 in in ADP bjos-8674720 137 2 our our PRON bjos-8674720 137 3 study study NOUN bjos-8674720 137 4 , , PUNCT bjos-8674720 137 5 we we PRON bjos-8674720 137 6 evaluate evaluate VERB bjos-8674720 137 7 the the DET bjos-8674720 137 8 effect effect NOUN bjos-8674720 137 9 of of ADP bjos-8674720 137 10 total total ADJ bjos-8674720 137 11 protein protein NOUN bjos-8674720 137 12 extract extract NOUN bjos-8674720 137 13 from from ADP bjos-8674720 137 14     SPACE bjos-8674720 137 15 aa aa NOUN bjos-8674720 137 16     SPACE bjos-8674720 137 17 serotype serotype PROPN bjos-8674720 137 18 jp2 jp2 PROPN bjos-8674720 137 19 , , PUNCT bjos-8674720 137 20 which which PRON bjos-8674720 137 21 also also ADV bjos-8674720 137 22 has have VERB bjos-8674720 137 23 a a DET bjos-8674720 137 24 destructive destructive ADJ bjos-8674720 137 25 effect effect NOUN bjos-8674720 137 26 . . PUNCT bjos-8674720 137 27     SPACE bjos-8674720 138 1 aa aa PROPN bjos-8674720 138 2 - - PUNCT bjos-8674720 138 3 jp2 jp2 PROPN bjos-8674720 138 4 is be AUX bjos-8674720 138 5 the the DET bjos-8674720 138 6 most most ADV bjos-8674720 138 7 cytotoxic cytotoxic ADJ bjos-8674720 138 8 serotype serotype NOUN bjos-8674720 138 9 and and CCONJ bjos-8674720 138 10 a a DET bjos-8674720 138 11 highly highly ADV bjos-8674720 138 12 pathogenic pathogenic ADJ bjos-8674720 138 13 species specie NOUN bjos-8674720 138 14 because because SCONJ bjos-8674720 138 15 its its PRON bjos-8674720 138 16 highly highly ADV bjos-8674720 138 17 leukotoxic leukotoxic ADJ bjos-8674720 138 18 strains strain NOUN bjos-8674720 138 19 can can AUX bjos-8674720 138 20 produce produce VERB bjos-8674720 138 21 10 10 NUM bjos-8674720 138 22 to to PART bjos-8674720 138 23 20 20 NUM bjos-8674720 138 24 - - NUM bjos-8674720 138 25 fold fold VERB bjos-8674720 138 26 more more ADJ bjos-8674720 138 27 toxin toxin NOUN bjos-8674720 138 28 than than ADP bjos-8674720 138 29 the the DET bjos-8674720 138 30 others22 others22 NOUN bjos-8674720 138 31 . . PUNCT bjos-8674720 139 1 it it PRON bjos-8674720 139 2 is be AUX bjos-8674720 139 3 well well ADV bjos-8674720 139 4 known know VERB bjos-8674720 139 5 that that SCONJ bjos-8674720 139 6     SPACE bjos-8674720 139 7 aa aa PROPN bjos-8674720 139 8 - - PUNCT bjos-8674720 139 9 jp2 jp2 PROPN bjos-8674720 139 10 interferes interfere VERB bjos-8674720 139 11 with with ADP bjos-8674720 139 12 the the DET bjos-8674720 139 13 host host NOUN bjos-8674720 139 14 ’s ’s PART bjos-8674720 139 15 innate innate ADJ bjos-8674720 139 16 immune immune ADJ bjos-8674720 139 17 defense defense NOUN bjos-8674720 139 18 and and CCONJ bjos-8674720 139 19 response11,12 response11,12 PROPN bjos-8674720 139 20 . . PUNCT bjos-8674720 140 1 studies study NOUN bjos-8674720 140 2 with with ADP bjos-8674720 140 3 oral oral ADJ bjos-8674720 140 4 cells cell NOUN bjos-8674720 140 5 showed show VERB bjos-8674720 140 6 that that SCONJ bjos-8674720 140 7 this this PRON bjos-8674720 140 8 could could AUX bjos-8674720 140 9 lead lead VERB bjos-8674720 140 10 to to ADP bjos-8674720 140 11 an an DET bjos-8674720 140 12 imbalanced imbalanced ADJ bjos-8674720 140 13 inflammatory inflammatory ADJ bjos-8674720 140 14 response12 response12 NOUN bjos-8674720 140 15 , , PUNCT bjos-8674720 140 16 which which PRON bjos-8674720 140 17 could could AUX bjos-8674720 140 18 affect affect VERB bjos-8674720 140 19 healing healing NOUN bjos-8674720 140 20 , , PUNCT bjos-8674720 140 21 as as SCONJ bjos-8674720 140 22 observed observe VERB bjos-8674720 140 23 in in ADP bjos-8674720 140 24 the the DET bjos-8674720 140 25 study study NOUN bjos-8674720 140 26 . . PUNCT bjos-8674720 141 1 all all DET bjos-8674720 141 2 this this PRON bjos-8674720 141 3 can can AUX bjos-8674720 141 4 disrupt disrupt VERB bjos-8674720 141 5 normal normal ADJ bjos-8674720 141 6 periodontal periodontal ADJ bjos-8674720 141 7 tissue tissue NOUN bjos-8674720 141 8 remodeling remodeling NOUN bjos-8674720 141 9 processes process NOUN bjos-8674720 141 10 , , PUNCT bjos-8674720 141 11 ultimately ultimately ADV bjos-8674720 141 12 promoting promote VERB bjos-8674720 141 13 collateral collateral ADJ bjos-8674720 141 14 tissue tissue NOUN bjos-8674720 141 15 damage damage NOUN bjos-8674720 141 16 , , PUNCT bjos-8674720 141 17 which which PRON bjos-8674720 141 18 explains explain VERB bjos-8674720 141 19 the the DET bjos-8674720 141 20 delay delay NOUN bjos-8674720 141 21 in in ADP bjos-8674720 141 22 healing22 healing22 PROPN bjos-8674720 141 23 . . PUNCT bjos-8674720 142 1 however however ADV bjos-8674720 142 2 , , PUNCT bjos-8674720 142 3 although although SCONJ bjos-8674720 142 4 potentially potentially ADV bjos-8674720 142 5 cytotoxic cytotoxic ADJ bjos-8674720 142 6 , , PUNCT bjos-8674720 142 7 up up ADP bjos-8674720 142 8 to to ADP bjos-8674720 142 9 now now ADV bjos-8674720 142 10 , , PUNCT bjos-8674720 142 11 there there PRON bjos-8674720 142 12 has have AUX bjos-8674720 142 13 been be AUX bjos-8674720 142 14 no no DET bjos-8674720 142 15 study study NOUN bjos-8674720 142 16 assessing assess VERB bjos-8674720 142 17 the the DET bjos-8674720 142 18 impact impact NOUN bjos-8674720 142 19 of of ADP bjos-8674720 142 20     SPACE bjos-8674720 142 21 aa aa NOUN bjos-8674720 142 22     SPACE bjos-8674720 142 23 on on ADP bjos-8674720 142 24 wound wound ADJ bjos-8674720 142 25 healing healing NOUN bjos-8674720 142 26 . . PUNCT bjos-8674720 143 1 the the DET bjos-8674720 143 2 present present ADJ bjos-8674720 143 3 study study NOUN bjos-8674720 143 4 shows show VERB bjos-8674720 143 5 that that SCONJ bjos-8674720 143 6 it it PRON bjos-8674720 143 7 negatively negatively ADV bjos-8674720 143 8 affected affect VERB bjos-8674720 143 9 the the DET bjos-8674720 143 10 healing healing NOUN bjos-8674720 143 11 process process NOUN bjos-8674720 143 12 since since SCONJ bjos-8674720 143 13 lower low ADJ bjos-8674720 143 14 wound wound NOUN bjos-8674720 143 15 closure closure NOUN bjos-8674720 143 16 could could AUX bjos-8674720 143 17 be be AUX bjos-8674720 143 18 seen see VERB bjos-8674720 143 19 when when SCONJ bjos-8674720 143 20 keratinocytes keratinocyte NOUN bjos-8674720 143 21 were be AUX bjos-8674720 143 22 cultivated cultivate VERB bjos-8674720 143 23 with with ADP bjos-8674720 143 24 total total ADJ bjos-8674720 143 25     SPACE bjos-8674720 143 26 aa aa NOUN bjos-8674720 143 27     SPACE bjos-8674720 143 28 protein protein NOUN bjos-8674720 143 29 . . PUNCT bjos-8674720 143 30     SPACE bjos-8674720 143 31 one one NUM bjos-8674720 143 32 factor factor NOUN bjos-8674720 143 33 that that PRON bjos-8674720 143 34 may may AUX bjos-8674720 143 35 explain explain VERB bjos-8674720 143 36 why why SCONJ bjos-8674720 143 37     SPACE bjos-8674720 143 38 aa aa NOUN bjos-8674720 143 39     SPACE bjos-8674720 143 40 decreases decrease VERB bjos-8674720 143 41 healing healing NOUN bjos-8674720 143 42 is be AUX bjos-8674720 143 43 that that SCONJ bjos-8674720 143 44 it it PRON bjos-8674720 143 45 disrupts disrupt VERB bjos-8674720 143 46 epithelial epithelial ADJ bjos-8674720 143 47 integrity integrity NOUN bjos-8674720 143 48 , , PUNCT bjos-8674720 143 49 facilitates facilitate VERB bjos-8674720 143 50 bacterial bacterial ADJ bjos-8674720 143 51 invasion invasion NOUN bjos-8674720 143 52 into into ADP bjos-8674720 143 53 deeper deep ADJ bjos-8674720 143 54 tissues tissue NOUN bjos-8674720 143 55 , , PUNCT bjos-8674720 143 56 and and CCONJ bjos-8674720 143 57 subsequently subsequently ADV bjos-8674720 143 58 destroys destroy VERB bjos-8674720 143 59 periodontal periodontal ADJ bjos-8674720 143 60 connective connective ADJ bjos-8674720 143 61 tissue23 tissue23 NOUN bjos-8674720 143 62 . . PUNCT bjos-8674720 144 1 disturbances disturbance NOUN bjos-8674720 144 2 caused cause VERB bjos-8674720 144 3 by by ADP bjos-8674720 144 4 the the DET bjos-8674720 144 5 cell cell NOUN bjos-8674720 144 6 - - PUNCT bjos-8674720 144 7 cell cell NOUN bjos-8674720 144 8 junction junction NOUN bjos-8674720 144 9 ’s ’s PART bjos-8674720 144 10 stability stability NOUN bjos-8674720 144 11 and and CCONJ bjos-8674720 144 12 dynamics dynamic NOUN bjos-8674720 144 13 can can AUX bjos-8674720 144 14 affect affect VERB bjos-8674720 144 15 the the DET bjos-8674720 144 16 epithelial epithelial ADJ bjos-8674720 144 17 layers layer NOUN bjos-8674720 144 18 ’ ' PUNCT bjos-8674720 144 19 barrier barrier NOUN bjos-8674720 144 20 properties property NOUN bjos-8674720 144 21 , , PUNCT bjos-8674720 144 22 harm harm VERB bjos-8674720 144 23 tissue tissue NOUN bjos-8674720 144 24 remodeling remodeling NOUN bjos-8674720 144 25 throughout throughout ADP bjos-8674720 144 26 development development NOUN bjos-8674720 144 27 , , PUNCT bjos-8674720 144 28 and and CCONJ bjos-8674720 144 29 impair impair VERB bjos-8674720 144 30 the the DET bjos-8674720 144 31 healing healing NOUN bjos-8674720 144 32 compared compare VERB bjos-8674720 144 33 to to ADP bjos-8674720 144 34 healthy healthy ADJ bjos-8674720 144 35 8 8 NUM bjos-8674720 144 36 mendes mende NOUN bjos-8674720 145 1 et et PROPN bjos-8674720 145 2 al al PROPN bjos-8674720 145 3 . . PROPN bjos-8674720 145 4 braz braz PROPN bjos-8674720 145 5 j j PROPN bjos-8674720 145 6 oral oral PROPN bjos-8674720 145 7 sci sci PROPN bjos-8674720 145 8 . . PUNCT bjos-8674720 146 1 2024;23 2024;23 NUM bjos-8674720 146 2 : : PUNCT bjos-8674720 146 3 e244720 e244720 NOUN bjos-8674720 146 4 tissue23 tissue23 NOUN bjos-8674720 146 5 . . PUNCT bjos-8674720 147 1 aa aa PRON bjos-8674720 147 2     SPACE bjos-8674720 147 3 can can AUX bjos-8674720 147 4 act act VERB bjos-8674720 147 5 on on ADP bjos-8674720 147 6 tissue tissue NOUN bjos-8674720 147 7 destruction destruction NOUN bjos-8674720 147 8 and and CCONJ bjos-8674720 147 9 delay delay VERB bjos-8674720 147 10 healing healing NOUN bjos-8674720 147 11 . . PUNCT bjos-8674720 148 1 a a DET bjos-8674720 148 2 study study NOUN bjos-8674720 148 3 demonstrated demonstrate VERB bjos-8674720 148 4 that that SCONJ bjos-8674720 148 5     SPACE bjos-8674720 148 6 aa aa NOUN bjos-8674720 148 7     SPACE bjos-8674720 148 8 secretes secrete NOUN bjos-8674720 148 9 a a DET bjos-8674720 148 10 cytolethal cytolethal NOUN bjos-8674720 148 11 distending distend VERB bjos-8674720 148 12 toxin toxin NOUN bjos-8674720 148 13 that that PRON bjos-8674720 148 14 likely likely ADV bjos-8674720 148 15 permeates permeate VERB bjos-8674720 148 16 the the DET bjos-8674720 148 17 widened widened ADJ bjos-8674720 148 18 interstitial interstitial ADJ bjos-8674720 148 19 spaces space NOUN bjos-8674720 148 20 of of ADP bjos-8674720 148 21 the the DET bjos-8674720 148 22 junctional junctional ADJ bjos-8674720 148 23 epithelium epithelium NOUN bjos-8674720 148 24 and and CCONJ bjos-8674720 148 25 in in ADP bjos-8674720 148 26 non non ADJ bjos-8674720 148 27 - - ADJ bjos-8674720 148 28 keratinized keratinized ADJ bjos-8674720 148 29 forms form NOUN bjos-8674720 148 30 of of ADP bjos-8674720 148 31 gingival gingival NOUN bjos-8674720 148 32 epithelium epithelium NOUN bjos-8674720 148 33 to to PART bjos-8674720 148 34 affect affect VERB bjos-8674720 148 35 their their PRON bjos-8674720 148 36 basal basal ADJ bjos-8674720 148 37 cell cell NOUN bjos-8674720 148 38 layers24 layers24 NOUN bjos-8674720 148 39 . . PUNCT bjos-8674720 149 1 the the DET bjos-8674720 149 2 distension distension NOUN bjos-8674720 149 3 of of ADP bjos-8674720 149 4 human human ADJ bjos-8674720 149 5 gingival gingival NOUN bjos-8674720 149 6 epithelial epithelial ADJ bjos-8674720 149 7 cells cell NOUN bjos-8674720 149 8 and and CCONJ bjos-8674720 149 9 the the DET bjos-8674720 149 10 dissolution dissolution NOUN bjos-8674720 149 11 of of ADP bjos-8674720 149 12 cell cell NOUN bjos-8674720 149 13 junctions junction NOUN bjos-8674720 149 14 may may AUX bjos-8674720 149 15 promote promote VERB bjos-8674720 149 16 broader broad ADJ bjos-8674720 149 17 penetration penetration NOUN bjos-8674720 149 18 of of ADP bjos-8674720 149 19 the the DET bjos-8674720 149 20 toxin toxin NOUN bjos-8674720 149 21 throughout throughout ADP bjos-8674720 149 22 the the DET bjos-8674720 149 23 tissue tissue NOUN bjos-8674720 149 24 , , PUNCT bjos-8674720 149 25 which which PRON bjos-8674720 149 26 may may AUX bjos-8674720 149 27 signal signal VERB bjos-8674720 149 28 the the DET bjos-8674720 149 29 recruitment recruitment NOUN bjos-8674720 149 30 of of ADP bjos-8674720 149 31 inflammatory inflammatory ADJ bjos-8674720 149 32 cells cell NOUN bjos-8674720 149 33 , , PUNCT bjos-8674720 149 34 consequently consequently ADV bjos-8674720 149 35 increasing increase VERB bjos-8674720 149 36 the the DET bjos-8674720 149 37 extent extent NOUN bjos-8674720 149 38 of of ADP bjos-8674720 149 39 tissue tissue NOUN bjos-8674720 149 40 damage damage NOUN bjos-8674720 149 41 due due ADP bjos-8674720 149 42 to to ADP bjos-8674720 149 43 the the DET bjos-8674720 149 44 production production NOUN bjos-8674720 149 45 of of ADP bjos-8674720 149 46 inflammatory inflammatory ADJ bjos-8674720 149 47 mediators mediator NOUN bjos-8674720 149 48 . . PUNCT bjos-8674720 150 1 this this DET bjos-8674720 150 2 study study NOUN bjos-8674720 150 3 showed show VERB bjos-8674720 150 4 a a DET bjos-8674720 150 5 significant significant ADJ bjos-8674720 150 6 difference difference NOUN bjos-8674720 150 7 at at ADP bjos-8674720 150 8 two two NUM bjos-8674720 150 9 follow follow VERB bjos-8674720 150 10 - - PUNCT bjos-8674720 150 11 up up NOUN bjos-8674720 150 12 times time NOUN bjos-8674720 150 13 ( ( PUNCT bjos-8674720 150 14 10 10 NUM bjos-8674720 150 15 and and CCONJ bjos-8674720 150 16 48 48 NUM bjos-8674720 150 17     SPACE bjos-8674720 150 18 hours hour NOUN bjos-8674720 150 19 ) ) PUNCT bjos-8674720 150 20 . . PUNCT bjos-8674720 151 1 on on ADP bjos-8674720 151 2 the the DET bjos-8674720 151 3 other other ADJ bjos-8674720 151 4 hand hand NOUN bjos-8674720 151 5 , , PUNCT bjos-8674720 151 6 no no DET bjos-8674720 151 7 statistical statistical ADJ bjos-8674720 151 8 difference difference NOUN bjos-8674720 151 9 could could AUX bjos-8674720 151 10 be be AUX bjos-8674720 151 11 identified identify VERB bjos-8674720 151 12 after after ADP bjos-8674720 151 13 5 5 NUM bjos-8674720 151 14 and and CCONJ bjos-8674720 151 15 24 24 NUM bjos-8674720 151 16     SPACE bjos-8674720 151 17 hours hour NOUN bjos-8674720 151 18 of of ADP bjos-8674720 151 19 exposure exposure NOUN bjos-8674720 151 20 . . PUNCT bjos-8674720 152 1 epithelial epithelial ADJ bjos-8674720 152 2 cells cell NOUN bjos-8674720 152 3 are be AUX bjos-8674720 152 4 the the DET bjos-8674720 152 5 first first ADJ bjos-8674720 152 6 to to PART bjos-8674720 152 7 arrive arrive VERB bjos-8674720 152 8 at at ADP bjos-8674720 152 9 the the DET bjos-8674720 152 10 wound wound NOUN bjos-8674720 152 11 site site NOUN bjos-8674720 152 12 , , PUNCT bjos-8674720 152 13 and and CCONJ bjos-8674720 152 14 the the DET bjos-8674720 152 15 epithelial epithelial ADJ bjos-8674720 152 16 healing healing NOUN bjos-8674720 152 17 process process NOUN bjos-8674720 152 18 is be AUX bjos-8674720 152 19 expected expect VERB bjos-8674720 152 20 to to PART bjos-8674720 152 21 occur occur VERB bjos-8674720 152 22 rapidly20 rapidly20 NOUN bjos-8674720 152 23 . . PUNCT bjos-8674720 153 1 there there PRON bjos-8674720 153 2 is be VERB bjos-8674720 153 3 a a DET bjos-8674720 153 4 response response NOUN bjos-8674720 153 5 time time NOUN bjos-8674720 153 6 for for ADP bjos-8674720 153 7 keratinocytes keratinocyte NOUN bjos-8674720 153 8 to to ADP bjos-8674720 153 9 the the DET bjos-8674720 153 10 aa aa NOUN bjos-8674720 153 11 protein protein NOUN bjos-8674720 153 12 extract extract NOUN bjos-8674720 153 13 ( ( PUNCT bjos-8674720 153 14 aape aape NOUN bjos-8674720 153 15 ) ) PUNCT bjos-8674720 153 16 exposure exposure NOUN bjos-8674720 153 17 . . PUNCT bjos-8674720 154 1 after after ADP bjos-8674720 154 2 exposure exposure NOUN bjos-8674720 154 3 to to PART bjos-8674720 154 4 aape aape VERB bjos-8674720 154 5 , , PUNCT bjos-8674720 154 6 the the DET bjos-8674720 154 7 cell cell NOUN bjos-8674720 154 8 recognizes recognize VERB bjos-8674720 154 9 the the DET bjos-8674720 154 10 pathogenic pathogenic ADJ bjos-8674720 154 11 protein protein NOUN bjos-8674720 154 12 through through ADP bjos-8674720 154 13 tlrs tlrs NOUN bjos-8674720 154 14 . . PUNCT bjos-8674720 155 1 its its PRON bjos-8674720 155 2 metabolic metabolic NOUN bjos-8674720 155 3 activity activity NOUN bjos-8674720 155 4 begins begin VERB bjos-8674720 155 5 to to PART bjos-8674720 155 6 be be AUX bjos-8674720 155 7 modulated modulate VERB bjos-8674720 155 8 , , PUNCT bjos-8674720 155 9 generating generate VERB bjos-8674720 155 10 a a DET bjos-8674720 155 11 lack lack NOUN bjos-8674720 155 12 of of ADP bjos-8674720 155 13 production production NOUN bjos-8674720 155 14 or or CCONJ bjos-8674720 155 15 defective defective ADJ bjos-8674720 155 16 production production NOUN bjos-8674720 155 17 of of ADP bjos-8674720 155 18 proteins protein NOUN bjos-8674720 155 19 responsible responsible ADJ bjos-8674720 155 20 for for ADP bjos-8674720 155 21 cell cell NOUN bjos-8674720 155 22 junctions23 junctions23 NOUN bjos-8674720 155 23 . . PUNCT bjos-8674720 156 1 this this DET bjos-8674720 156 2 entire entire ADJ bjos-8674720 156 3 process process NOUN bjos-8674720 156 4 can can AUX bjos-8674720 156 5 take take VERB bjos-8674720 156 6 hours hour NOUN bjos-8674720 156 7 to to PART bjos-8674720 156 8 occur occur VERB bjos-8674720 156 9 . . PUNCT bjos-8674720 157 1 this this PRON bjos-8674720 157 2 is be AUX bjos-8674720 157 3 the the DET bjos-8674720 157 4 plausibility plausibility NOUN bjos-8674720 157 5 of of ADP bjos-8674720 157 6 the the DET bjos-8674720 157 7 absence absence NOUN bjos-8674720 157 8 of of ADP bjos-8674720 157 9 difference difference NOUN bjos-8674720 157 10 in in ADP bjos-8674720 157 11 the the DET bjos-8674720 157 12 cell cell NOUN bjos-8674720 157 13 response response NOUN bjos-8674720 157 14 after after ADP bjos-8674720 157 15 5 5 NUM bjos-8674720 157 16     SPACE bjos-8674720 157 17 hours hour NOUN bjos-8674720 157 18 in in ADP bjos-8674720 157 19 this this DET bjos-8674720 157 20 study study NOUN bjos-8674720 157 21 . . PUNCT bjos-8674720 158 1 after after ADP bjos-8674720 158 2 this this DET bjos-8674720 158 3 process process NOUN bjos-8674720 158 4 , , PUNCT bjos-8674720 158 5 cellular cellular ADJ bjos-8674720 158 6 activity activity NOUN bjos-8674720 158 7 is be AUX bjos-8674720 158 8 damped damp VERB bjos-8674720 158 9 by by ADP bjos-8674720 158 10     SPACE bjos-8674720 158 11 aa aa NOUN bjos-8674720 158 12     SPACE bjos-8674720 158 13 toxins toxin NOUN bjos-8674720 158 14 , , PUNCT bjos-8674720 158 15 slowing slow VERB bjos-8674720 158 16 down down ADP bjos-8674720 158 17 the the DET bjos-8674720 158 18 epithelial epithelial ADJ bjos-8674720 158 19 repair repair NOUN bjos-8674720 158 20 , , PUNCT bjos-8674720 158 21 which which PRON bjos-8674720 158 22 explains explain VERB bjos-8674720 158 23 the the DET bjos-8674720 158 24 later later ADJ bjos-8674720 158 25 closure closure NOUN bjos-8674720 158 26 response response NOUN bjos-8674720 158 27 for for ADP bjos-8674720 158 28 the the DET bjos-8674720 158 29 test test NOUN bjos-8674720 158 30 group group NOUN bjos-8674720 158 31 ( ( PUNCT bjos-8674720 158 32 48 48 NUM bjos-8674720 158 33     SPACE bjos-8674720 158 34 hours hour NOUN bjos-8674720 158 35 ) ) PUNCT bjos-8674720 158 36 . . PUNCT bjos-8674720 159 1 the the DET bjos-8674720 159 2 results result NOUN bjos-8674720 159 3 achieved achieve VERB bjos-8674720 159 4 in in ADP bjos-8674720 159 5 this this DET bjos-8674720 159 6 study study NOUN bjos-8674720 159 7 elucidate elucidate VERB bjos-8674720 159 8 a a DET bjos-8674720 159 9 slight slight ADJ bjos-8674720 159 10 portion portion NOUN bjos-8674720 159 11 of of ADP bjos-8674720 159 12 the the DET bjos-8674720 159 13 etiopathogenic etiopathogenic ADJ bjos-8674720 159 14 aspects aspect NOUN bjos-8674720 159 15 of of ADP bjos-8674720 159 16 periodontal periodontal ADJ bjos-8674720 159 17 disease disease NOUN bjos-8674720 159 18 . . PUNCT bjos-8674720 160 1 in in ADP bjos-8674720 160 2 periodontitis periodontitis NOUN bjos-8674720 160 3 , , PUNCT bjos-8674720 160 4 the the DET bjos-8674720 160 5 dysbiotic dysbiotic ADJ bjos-8674720 160 6 presence presence NOUN bjos-8674720 160 7 of of ADP bjos-8674720 160 8 periodontopathogens periodontopathogen NOUN bjos-8674720 160 9 such such ADJ bjos-8674720 160 10 as as ADP bjos-8674720 160 11 aa aa NOUN bjos-8674720 160 12 and and CCONJ bjos-8674720 160 13 pg pg X bjos-8674720 160 14 at at ADP bjos-8674720 160 15 subgingival subgingival ADJ bjos-8674720 160 16 biofilm biofilm NOUN bjos-8674720 160 17 harms harm VERB bjos-8674720 160 18 gingival gingival ADJ bjos-8674720 160 19 tissue tissue NOUN bjos-8674720 160 20 through through ADP bjos-8674720 160 21 the the DET bjos-8674720 160 22 bacterial bacterial ADJ bjos-8674720 160 23 adherence adherence NOUN bjos-8674720 160 24 to to ADP bjos-8674720 160 25 the the DET bjos-8674720 160 26 epithelial epithelial ADJ bjos-8674720 160 27 cells cell NOUN bjos-8674720 160 28 , , PUNCT bjos-8674720 160 29 which which PRON bjos-8674720 160 30 colonizes colonize VERB bjos-8674720 160 31 the the DET bjos-8674720 160 32 connective connective ADJ bjos-8674720 160 33 tissue tissue NOUN bjos-8674720 160 34 , , PUNCT bjos-8674720 160 35 stimulating stimulate VERB bjos-8674720 160 36 the the DET bjos-8674720 160 37 cells cell NOUN bjos-8674720 160 38 to to PART bjos-8674720 160 39 secrete secrete VERB bjos-8674720 160 40 cytokines cytokine NOUN bjos-8674720 160 41 responsible responsible ADJ bjos-8674720 160 42 for for ADP bjos-8674720 160 43 recruiting recruit VERB bjos-8674720 160 44 inflammatory inflammatory ADJ bjos-8674720 160 45 cells cell NOUN bjos-8674720 160 46 by by ADP bjos-8674720 160 47 inducing induce VERB bjos-8674720 160 48 changes change NOUN bjos-8674720 160 49 in in ADP bjos-8674720 160 50 signaling signal VERB bjos-8674720 160 51 pathways pathway NOUN bjos-8674720 160 52 and and CCONJ bjos-8674720 160 53 gene gene NOUN bjos-8674720 160 54 expression25 expression25 PROPN bjos-8674720 160 55 . . PUNCT bjos-8674720 161 1 this this DET bjos-8674720 161 2 methodology methodology NOUN bjos-8674720 161 3 used use VERB bjos-8674720 161 4 aape aape NOUN bjos-8674720 161 5 for for ADP bjos-8674720 161 6 keratinocyte keratinocyte NOUN bjos-8674720 161 7 stimulation stimulation NOUN bjos-8674720 161 8 because because SCONJ bjos-8674720 161 9 of of ADP bjos-8674720 161 10 its its PRON bjos-8674720 161 11 proximity proximity NOUN bjos-8674720 161 12 to to ADP bjos-8674720 161 13 periodontitis periodontitis NOUN bjos-8674720 161 14 . . PUNCT bjos-8674720 162 1 although although SCONJ bjos-8674720 162 2 there there PRON bjos-8674720 162 3 are be VERB bjos-8674720 162 4 six six NUM bjos-8674720 162 5 serotypes serotype NOUN bjos-8674720 162 6 of of ADP bjos-8674720 162 7 aa aa NOUN bjos-8674720 162 8 ( ( PUNCT bjos-8674720 162 9 a a NOUN bjos-8674720 162 10 – – PUNCT bjos-8674720 162 11 g g NOUN bjos-8674720 162 12 ) ) PUNCT bjos-8674720 162 13 , , PUNCT bjos-8674720 162 14 serotype serotype NOUN bjos-8674720 162 15 b b PROPN bjos-8674720 162 16 ( ( PUNCT bjos-8674720 162 17 jp2 jp2 PROPN bjos-8674720 162 18     SPACE bjos-8674720 162 19 genotype genotype NOUN bjos-8674720 162 20 ) ) PUNCT bjos-8674720 162 21 is be AUX bjos-8674720 162 22 the the DET bjos-8674720 162 23 one one NOUN bjos-8674720 162 24 that that PRON bjos-8674720 162 25 is be AUX bjos-8674720 162 26 associated associate VERB bjos-8674720 162 27 with with ADP bjos-8674720 162 28 a a DET bjos-8674720 162 29 greater great ADJ bjos-8674720 162 30 risk risk NOUN bjos-8674720 162 31 of of ADP bjos-8674720 162 32 periodontal periodontal ADJ bjos-8674720 162 33 insertion insertion NOUN bjos-8674720 162 34 loss22 loss22 NOUN bjos-8674720 162 35 . . PUNCT bjos-8674720 163 1 in in ADP bjos-8674720 163 2 our our PRON bjos-8674720 163 3 study study NOUN bjos-8674720 163 4 , , PUNCT bjos-8674720 163 5 the the DET bjos-8674720 163 6 total total ADJ bjos-8674720 163 7 protein protein NOUN bjos-8674720 163 8 of of ADP bjos-8674720 163 9 this this DET bjos-8674720 163 10 more more ADJ bjos-8674720 163 11 cytotoxic cytotoxic ADJ bjos-8674720 163 12 strain strain NOUN bjos-8674720 163 13 was be AUX bjos-8674720 163 14 used use VERB bjos-8674720 163 15 , , PUNCT bjos-8674720 163 16 and and CCONJ bjos-8674720 163 17 several several ADJ bjos-8674720 163 18 virulent virulent ADJ bjos-8674720 163 19 aspects aspect NOUN bjos-8674720 163 20 were be AUX bjos-8674720 163 21 given give VERB bjos-8674720 163 22 to to ADP bjos-8674720 163 23 cells cell NOUN bjos-8674720 163 24 . . PUNCT bjos-8674720 164 1 given give VERB bjos-8674720 164 2 the the DET bjos-8674720 164 3 results result NOUN bjos-8674720 164 4 obtained obtain VERB bjos-8674720 164 5 , , PUNCT bjos-8674720 164 6 in in ADP bjos-8674720 164 7 addition addition NOUN bjos-8674720 164 8 to to ADP bjos-8674720 164 9 being be AUX bjos-8674720 164 10 a a DET bjos-8674720 164 11 trigger trigger NOUN bjos-8674720 164 12 for for ADP bjos-8674720 164 13 the the DET bjos-8674720 164 14 onset onset NOUN bjos-8674720 164 15 of of ADP bjos-8674720 164 16 the the DET bjos-8674720 164 17 disease disease NOUN bjos-8674720 164 18 , , PUNCT bjos-8674720 164 19 the the DET bjos-8674720 164 20 presence presence NOUN bjos-8674720 164 21 of of ADP bjos-8674720 164 22 aa aa NOUN bjos-8674720 164 23 can can AUX bjos-8674720 164 24 also also ADV bjos-8674720 164 25 alter alter VERB bjos-8674720 164 26 tissue tissue NOUN bjos-8674720 164 27 healing healing NOUN bjos-8674720 164 28 after after ADP bjos-8674720 164 29 initial initial ADJ bjos-8674720 164 30 damage damage NOUN bjos-8674720 164 31 or or CCONJ bjos-8674720 164 32 periodontal periodontal ADJ bjos-8674720 164 33 instrumentation instrumentation NOUN bjos-8674720 164 34 . . PUNCT bjos-8674720 165 1 this this DET bjos-8674720 165 2 way way NOUN bjos-8674720 165 3 , , PUNCT bjos-8674720 165 4 clinicians clinician NOUN bjos-8674720 165 5 must must AUX bjos-8674720 165 6 focus focus VERB bjos-8674720 165 7 more more ADV bjos-8674720 165 8 on on ADP bjos-8674720 165 9 controlling control VERB bjos-8674720 165 10 subgingival subgingival ADJ bjos-8674720 165 11 plaque plaque NOUN bjos-8674720 165 12 and and CCONJ bjos-8674720 165 13 dysbiosis dysbiosis NOUN bjos-8674720 165 14 after after ADP bjos-8674720 165 15 periodontal periodontal ADJ bjos-8674720 165 16 treatment treatment NOUN bjos-8674720 165 17 and and CCONJ bjos-8674720 165 18 other other ADJ bjos-8674720 165 19 procedures procedure NOUN bjos-8674720 165 20 involving involve VERB bjos-8674720 165 21 periodontal periodontal ADJ bjos-8674720 165 22 tissues tissue NOUN bjos-8674720 165 23 and and CCONJ bjos-8674720 165 24 re re NOUN bjos-8674720 165 25 - - NOUN bjos-8674720 165 26 epithelization epithelization NOUN bjos-8674720 165 27 , , PUNCT bjos-8674720 165 28 e.g. e.g. ADV bjos-8674720 165 29 , , PUNCT bjos-8674720 165 30 aesthetic aesthetic ADJ bjos-8674720 165 31 crown crown NOUN bjos-8674720 165 32 lengthening lengthening NOUN bjos-8674720 165 33 . . PUNCT bjos-8674720 166 1 in in ADP bjos-8674720 166 2 this this DET bjos-8674720 166 3 study study NOUN bjos-8674720 166 4 , , PUNCT bjos-8674720 166 5 we we PRON bjos-8674720 166 6 assessed assess VERB bjos-8674720 166 7 that that SCONJ bjos-8674720 166 8 wound wound NOUN bjos-8674720 166 9 healing healing NOUN bjos-8674720 166 10 could could AUX bjos-8674720 166 11 indeed indeed ADV bjos-8674720 166 12 be be AUX bjos-8674720 166 13 influenced influence VERB bjos-8674720 166 14 by by ADP bjos-8674720 166 15 a a DET bjos-8674720 166 16 bacterial bacterial ADJ bjos-8674720 166 17 pathogen pathogen NOUN bjos-8674720 166 18 such such ADJ bjos-8674720 166 19 as as ADP bjos-8674720 166 20     SPACE bjos-8674720 166 21 aa aa NOUN bjos-8674720 166 22 ; ; PUNCT bjos-8674720 166 23 however however ADV bjos-8674720 166 24 , , PUNCT bjos-8674720 166 25 this this DET bjos-8674720 166 26 study study NOUN bjos-8674720 166 27 presented present VERB bjos-8674720 166 28 some some DET bjos-8674720 166 29 limitations limitation NOUN bjos-8674720 166 30 : : PUNCT bjos-8674720 166 31 the the DET bjos-8674720 166 32 lack lack NOUN bjos-8674720 166 33 of of ADP bjos-8674720 166 34 an an DET bjos-8674720 166 35     SPACE bjos-8674720 166 36 in in ADP bjos-8674720 166 37 vivo vivo NOUN bjos-8674720 166 38     SPACE bjos-8674720 166 39 study study NOUN bjos-8674720 166 40 to to PART bjos-8674720 166 41 see see VERB bjos-8674720 166 42 how how SCONJ bjos-8674720 166 43 the the DET bjos-8674720 166 44 subgingival subgingival ADJ bjos-8674720 166 45 microbiota microbiota NOUN bjos-8674720 166 46 and and CCONJ bjos-8674720 166 47 a a DET bjos-8674720 166 48 complete complete ADJ bjos-8674720 166 49 biofilm biofilm NOUN bjos-8674720 166 50 with with ADP bjos-8674720 166 51 a a DET bjos-8674720 166 52 larger large ADJ bjos-8674720 166 53 number number NOUN bjos-8674720 166 54 of of ADP bjos-8674720 166 55 pathogens pathogen NOUN bjos-8674720 166 56 , , PUNCT bjos-8674720 166 57 as as ADP bjos-8674720 166 58 in in ADP bjos-8674720 166 59 periodontitis periodontitis NOUN bjos-8674720 166 60 , , PUNCT bjos-8674720 166 61 can can AUX bjos-8674720 166 62 affect affect VERB bjos-8674720 166 63 oral oral ADJ bjos-8674720 166 64 tissue tissue NOUN bjos-8674720 166 65 healing healing NOUN bjos-8674720 166 66 , , PUNCT bjos-8674720 166 67 and and CCONJ bjos-8674720 166 68 the the DET bjos-8674720 166 69 lack lack NOUN bjos-8674720 166 70 of of ADP bjos-8674720 166 71 another another DET bjos-8674720 166 72 cell cell NOUN bjos-8674720 166 73 type type NOUN bjos-8674720 166 74 , , PUNCT bjos-8674720 166 75 such such ADJ bjos-8674720 166 76 as as ADP bjos-8674720 166 77 fibroblasts fibroblast NOUN bjos-8674720 166 78 , , PUNCT bjos-8674720 166 79 for for ADP bjos-8674720 166 80 greater great ADJ bjos-8674720 166 81 comparison comparison NOUN bjos-8674720 166 82 effect effect NOUN bjos-8674720 166 83 in in ADP bjos-8674720 166 84 the the DET bjos-8674720 166 85 results result NOUN bjos-8674720 166 86 . . PUNCT bjos-8674720 167 1 therefore therefore ADV bjos-8674720 167 2 , , PUNCT bjos-8674720 167 3 it it PRON bjos-8674720 167 4 would would AUX bjos-8674720 167 5 be be AUX bjos-8674720 167 6 necessary necessary ADJ bjos-8674720 167 7 to to PART bjos-8674720 167 8 include include VERB bjos-8674720 167 9 at at ADV bjos-8674720 167 10 least least ADV bjos-8674720 167 11 one one NUM bjos-8674720 167 12 more more ADJ bjos-8674720 167 13 pathogen pathogen NOUN bjos-8674720 167 14 and and CCONJ bjos-8674720 167 15 cell cell NOUN bjos-8674720 167 16 type type NOUN bjos-8674720 167 17 for for ADP bjos-8674720 167 18 a a DET bjos-8674720 167 19 better well ADJ bjos-8674720 167 20     SPACE bjos-8674720 167 21 in in ADP bjos-8674720 167 22 vitro vitro X bjos-8674720 167 23     SPACE bjos-8674720 167 24 study study NOUN bjos-8674720 167 25 and and CCONJ bjos-8674720 167 26 to to PART bjos-8674720 167 27 evaluate evaluate VERB bjos-8674720 167 28 the the DET bjos-8674720 167 29 possibility possibility NOUN bjos-8674720 167 30 of of ADP bjos-8674720 167 31 carrying carry VERB bjos-8674720 167 32 out out ADP bjos-8674720 167 33 additional additional ADJ bjos-8674720 167 34     SPACE bjos-8674720 167 35 in in ADP bjos-8674720 167 36 vivo vivo ADJ bjos-8674720 167 37     SPACE bjos-8674720 167 38 studies study NOUN bjos-8674720 167 39 to to PART bjos-8674720 167 40 determine determine VERB bjos-8674720 167 41 the the DET bjos-8674720 167 42 impact impact NOUN bjos-8674720 167 43 of of ADP bjos-8674720 167 44 oral oral ADJ bjos-8674720 167 45 bacteria bacteria NOUN bjos-8674720 167 46 on on ADP bjos-8674720 167 47 wound wound ADJ bjos-8674720 167 48 healing healing NOUN bjos-8674720 167 49     SPACE bjos-8674720 167 50 in in ADP bjos-8674720 167 51 vivo vivo NOUN bjos-8674720 167 52 . . PUNCT bjos-8674720 168 1 in in ADP bjos-8674720 168 2 conclusion conclusion NOUN bjos-8674720 168 3 , , PUNCT bjos-8674720 168 4 the the DET bjos-8674720 168 5 pathogen pathogen NOUN bjos-8674720 168 6     SPACE bjos-8674720 168 7 aggregatibacter aggregatibacter NOUN bjos-8674720 168 8 actinomycetemcomitans actinomycetemcomitan NOUN bjos-8674720 168 9     SPACE bjos-8674720 168 10 can can AUX bjos-8674720 168 11 interfere interfere VERB bjos-8674720 168 12 with with ADP bjos-8674720 168 13 wound wound ADJ bjos-8674720 168 14 closure closure NOUN bjos-8674720 168 15 by by ADP bjos-8674720 168 16 keratinocytes keratinocyte NOUN bjos-8674720 168 17 . . PUNCT bjos-8674720 169 1 this this PRON bjos-8674720 169 2 may may AUX bjos-8674720 169 3 be be AUX bjos-8674720 169 4 due due ADJ bjos-8674720 169 5 to to ADP bjos-8674720 169 6 disturbances disturbance NOUN bjos-8674720 169 7 caused cause VERB bjos-8674720 169 8 by by ADP bjos-8674720 169 9 the the DET bjos-8674720 169 10 stability stability NOUN bjos-8674720 169 11 and and CCONJ bjos-8674720 169 12 dynamics dynamic NOUN bjos-8674720 169 13 of of ADP bjos-8674720 169 14 the the DET bjos-8674720 169 15 cell cell NOUN bjos-8674720 169 16 - - PUNCT bjos-8674720 169 17 cell cell NOUN bjos-8674720 169 18 junction junction NOUN bjos-8674720 169 19 caused cause VERB bjos-8674720 169 20 by by ADP bjos-8674720 169 21     SPACE bjos-8674720 169 22 aa aa NOUN bjos-8674720 169 23 . . PUNCT bjos-8674720 169 24     SPACE bjos-8674720 169 25 9 9 NUM bjos-8674720 169 26 mendes mende NOUN bjos-8674720 170 1 et et PROPN bjos-8674720 170 2 al al PROPN bjos-8674720 170 3 . . PROPN bjos-8674720 170 4 braz braz PROPN bjos-8674720 170 5 j j PROPN bjos-8674720 170 6 oral oral PROPN bjos-8674720 170 7 sci sci PROPN bjos-8674720 170 8 . . PUNCT bjos-8674720 171 1 2024;23 2024;23 NUM bjos-8674720 171 2 : : PUNCT bjos-8674720 171 3 e244720 e244720 NOUN bjos-8674720 171 4 acknowledgments acknowledgment NOUN bjos-8674720 171 5 this this DET bjos-8674720 171 6 study study NOUN bjos-8674720 171 7 was be AUX bjos-8674720 171 8 financed finance VERB bjos-8674720 171 9 by by ADP bjos-8674720 171 10 the the DET bjos-8674720 171 11 national national PROPN bjos-8674720 171 12 council council PROPN bjos-8674720 171 13 for for ADP bjos-8674720 171 14 scientific scientific ADJ bjos-8674720 171 15 and and CCONJ bjos-8674720 171 16 technological technological ADJ bjos-8674720 171 17 development development NOUN bjos-8674720 171 18 – – PUNCT bjos-8674720 171 19 brazil brazil PROPN bjos-8674720 171 20 ( ( PUNCT bjos-8674720 171 21 capes cape NOUN bjos-8674720 171 22 ) ) PUNCT bjos-8674720 171 23 – – PUNCT bjos-8674720 171 24 finance finance NOUN bjos-8674720 171 25 code code NOUN bjos-8674720 171 26 001 001 NOUN bjos-8674720 171 27 . . PUNCT bjos-8674720 172 1 the the DET bjos-8674720 172 2 authors author NOUN bjos-8674720 172 3 also also ADV bjos-8674720 172 4 declare declare VERB bjos-8674720 172 5 no no DET bjos-8674720 172 6 conflicts conflict NOUN bjos-8674720 172 7 of of ADP bjos-8674720 172 8 interest interest NOUN bjos-8674720 172 9 in in ADP bjos-8674720 172 10 this this DET bjos-8674720 172 11 study study NOUN bjos-8674720 172 12 . . PUNCT bjos-8674720 173 1 funding funding NOUN bjos-8674720 173 2 sources source NOUN bjos-8674720 173 3 this this DET bjos-8674720 173 4 study study NOUN bjos-8674720 173 5 did do AUX bjos-8674720 173 6 not not PART bjos-8674720 173 7 receive receive VERB bjos-8674720 173 8 any any DET bjos-8674720 173 9 specific specific ADJ bjos-8674720 173 10 grant grant NOUN bjos-8674720 173 11 from from ADP bjos-8674720 173 12 funding fund VERB bjos-8674720 173 13 agencies agency NOUN bjos-8674720 173 14 in in ADP bjos-8674720 173 15 the the DET bjos-8674720 173 16 public public ADJ bjos-8674720 173 17 , , PUNCT bjos-8674720 173 18 commercial commercial ADJ bjos-8674720 173 19 , , PUNCT bjos-8674720 173 20 or or CCONJ bjos-8674720 173 21 not not PART bjos-8674720 173 22 - - PUNCT bjos-8674720 173 23 for for ADP bjos-8674720 173 24 - - PUNCT bjos-8674720 173 25 profit profit NOUN bjos-8674720 173 26 sectors sector NOUN bjos-8674720 173 27 . . PUNCT bjos-8674720 174 1 conflict conflict NOUN bjos-8674720 174 2 of of ADP bjos-8674720 174 3 interest interest NOUN bjos-8674720 174 4 the the DET bjos-8674720 174 5 authors author NOUN bjos-8674720 174 6 have have VERB bjos-8674720 174 7 no no DET bjos-8674720 174 8 conflict conflict NOUN bjos-8674720 174 9 of of ADP bjos-8674720 174 10 interest interest NOUN bjos-8674720 174 11 to to PART bjos-8674720 174 12 disclose disclose VERB bjos-8674720 174 13 . . PUNCT bjos-8674720 175 1 data datum NOUN bjos-8674720 175 2 availability availability NOUN bjos-8674720 175 3 datasets dataset NOUN bjos-8674720 175 4 related relate VERB bjos-8674720 175 5 to to ADP bjos-8674720 175 6 this this DET bjos-8674720 175 7 article article NOUN bjos-8674720 175 8 will will AUX bjos-8674720 175 9 be be AUX bjos-8674720 175 10 available available ADJ bjos-8674720 175 11 to to ADP bjos-8674720 175 12 the the DET bjos-8674720 175 13 corresponding corresponding ADJ bjos-8674720 175 14 author author NOUN bjos-8674720 175 15 upon upon SCONJ bjos-8674720 175 16 request request NOUN bjos-8674720 175 17 . . PUNCT bjos-8674720 176 1 author author NOUN bjos-8674720 176 2 contribution contribution PROPN bjos-8674720 176 3 bianca bianca PROPN bjos-8674720 176 4 carvalho carvalho PROPN bjos-8674720 176 5 mendes mende NOUN bjos-8674720 176 6 : : PUNCT bjos-8674720 176 7 data data NOUN bjos-8674720 176 8 collection collection NOUN bjos-8674720 176 9 , , PUNCT bjos-8674720 176 10 writing write VERB bjos-8674720 176 11 the the DET bjos-8674720 176 12 manuscript manuscript NOUN bjos-8674720 176 13 . . PUNCT bjos-8674720 177 1 camila camila PROPN bjos-8674720 177 2 schmidt schmidt PROPN bjos-8674720 177 3 stolf stolf PROPN bjos-8674720 177 4 : : PUNCT bjos-8674720 177 5 conception conception NOUN bjos-8674720 177 6 and and CCONJ bjos-8674720 177 7 design design NOUN bjos-8674720 177 8 of of ADP bjos-8674720 177 9 the the DET bjos-8674720 177 10 study study NOUN bjos-8674720 177 11 , , PUNCT bjos-8674720 177 12 data datum NOUN bjos-8674720 177 13 analysis analysis NOUN bjos-8674720 177 14 , , PUNCT bjos-8674720 177 15 writing write VERB bjos-8674720 177 16 the the DET bjos-8674720 177 17 manuscript manuscript NOUN bjos-8674720 177 18 . . PUNCT bjos-8674720 178 1 hélvis hélvis PROPN bjos-8674720 178 2 enri enri PROPN bjos-8674720 178 3 de de PROPN bjos-8674720 178 4 sousa sousa PROPN bjos-8674720 178 5 paz paz PROPN bjos-8674720 178 6 : : PUNCT bjos-8674720 178 7 review review NOUN bjos-8674720 178 8 and and CCONJ bjos-8674720 178 9 editing edit VERB bjos-8674720 178 10 , , PUNCT bjos-8674720 178 11 writing write VERB bjos-8674720 178 12 the the DET bjos-8674720 178 13 manuscript manuscript NOUN bjos-8674720 178 14 . . PUNCT bjos-8674720 179 1 letícia letícia PROPN bjos-8674720 179 2 sandoli sandoli NOUN bjos-8674720 179 3 arroteia arroteia NOUN bjos-8674720 179 4 : : PUNCT bjos-8674720 179 5 data datum NOUN bjos-8674720 179 6 analysis analysis NOUN bjos-8674720 179 7 , , PUNCT bjos-8674720 179 8 interpretation interpretation NOUN bjos-8674720 179 9 and and CCONJ bjos-8674720 179 10 statistics statistic NOUN bjos-8674720 179 11 . . PUNCT bjos-8674720 180 1 lucas lucas PROPN bjos-8674720 180 2 de de PROPN bjos-8674720 180 3 paula paula PROPN bjos-8674720 180 4 ramos ramos PROPN bjos-8674720 180 5 : : PUNCT bjos-8674720 180 6 data data NOUN bjos-8674720 180 7 collection collection NOUN bjos-8674720 180 8 , , PUNCT bjos-8674720 180 9 interpretation interpretation NOUN bjos-8674720 180 10 and and CCONJ bjos-8674720 180 11 statistics statistic NOUN bjos-8674720 180 12 . . PUNCT bjos-8674720 181 1 mauro mauro PROPN bjos-8674720 181 2 pedrine pedrine PROPN bjos-8674720 181 3 santamaria santamaria PROPN bjos-8674720 181 4 : : PUNCT bjos-8674720 181 5 data data NOUN bjos-8674720 181 6 collection collection NOUN bjos-8674720 181 7 , , PUNCT bjos-8674720 181 8 interpretation interpretation NOUN bjos-8674720 181 9 and and CCONJ bjos-8674720 181 10 statistics statistic NOUN bjos-8674720 181 11 . . PUNCT bjos-8674720 182 1 karina karina PROPN bjos-8674720 182 2 gonzales gonzales PROPN bjos-8674720 182 3 silvério silvério PROPN bjos-8674720 182 4 ruiz ruiz PROPN bjos-8674720 182 5 : : PUNCT bjos-8674720 182 6 conception conception NOUN bjos-8674720 182 7 and and CCONJ bjos-8674720 182 8 design design NOUN bjos-8674720 182 9 of of ADP bjos-8674720 182 10 the the DET bjos-8674720 182 11 study study NOUN bjos-8674720 182 12 , , PUNCT bjos-8674720 182 13 review review NOUN bjos-8674720 182 14 and and CCONJ bjos-8674720 182 15 editing editing NOUN bjos-8674720 182 16 . . PUNCT bjos-8674720 183 1 mabelle mabelle PROPN bjos-8674720 183 2 de de PROPN bjos-8674720 183 3 freitas freitas PROPN bjos-8674720 183 4 monteiro monteiro PROPN bjos-8674720 183 5 : : PUNCT bjos-8674720 183 6 writing write VERB bjos-8674720 183 7 the the DET bjos-8674720 183 8 manuscript manuscript NOUN bjos-8674720 183 9 , , PUNCT bjos-8674720 183 10 review review NOUN bjos-8674720 183 11 and and CCONJ bjos-8674720 183 12 editing editing NOUN bjos-8674720 183 13 . . PUNCT bjos-8674720 184 1 renato renato PROPN bjos-8674720 184 2 corrêa corrêa PROPN bjos-8674720 184 3 viana viana PROPN bjos-8674720 184 4 casarin casarin PROPN bjos-8674720 184 5 : : PUNCT bjos-8674720 184 6 conception conception NOUN bjos-8674720 184 7 and and CCONJ bjos-8674720 184 8 design design NOUN bjos-8674720 184 9 of of ADP bjos-8674720 184 10 the the DET bjos-8674720 184 11 study study NOUN bjos-8674720 184 12 , , PUNCT bjos-8674720 184 13 writing write VERB bjos-8674720 184 14 the the DET bjos-8674720 184 15 manuscript manuscript NOUN bjos-8674720 184 16 , , PUNCT bjos-8674720 184 17 review review NOUN bjos-8674720 184 18 and and CCONJ bjos-8674720 184 19 editing editing NOUN bjos-8674720 184 20 . . PUNCT bjos-8674720 185 1 we we PRON bjos-8674720 185 2 declare declare VERB bjos-8674720 185 3 that that SCONJ bjos-8674720 185 4 all all DET bjos-8674720 185 5 authors author NOUN bjos-8674720 185 6 actively actively ADV bjos-8674720 185 7 participated participate VERB bjos-8674720 185 8 in in ADP bjos-8674720 185 9 the the DET bjos-8674720 185 10 manuscript manuscript NOUN bjos-8674720 185 11 findings finding NOUN bjos-8674720 185 12 , , PUNCT bjos-8674720 185 13 revised revise VERB bjos-8674720 185 14 and and CCONJ bjos-8674720 185 15 approved approve VERB bjos-8674720 185 16 the the DET bjos-8674720 185 17 final final ADJ bjos-8674720 185 18 version version NOUN bjos-8674720 185 19 of of ADP bjos-8674720 185 20 the the DET bjos-8674720 185 21 manuscript manuscript NOUN bjos-8674720 185 22 . . PUNCT bjos-8674720 186 1 references reference NOUN bjos-8674720 186 2 1 1 NUM bjos-8674720 186 3 . . PUNCT bjos-8674720 186 4 mohammed mohammed PROPN bjos-8674720 186 5 bm bm PROPN bjos-8674720 186 6 , , PUNCT bjos-8674720 186 7 fisher fisher PROPN bjos-8674720 186 8 bj bj PROPN bjos-8674720 186 9 , , PUNCT bjos-8674720 186 10 kraskauskas kraskauskas NOUN bjos-8674720 186 11 d d NOUN bjos-8674720 186 12 , , PUNCT bjos-8674720 186 13 ward ward PROPN bjos-8674720 186 14 s s PROPN bjos-8674720 186 15 , , PUNCT bjos-8674720 186 16 wayne wayne PROPN bjos-8674720 186 17 js js PROPN bjos-8674720 186 18 , , PUNCT bjos-8674720 186 19 brophy brophy PROPN bjos-8674720 186 20 df df PROPN bjos-8674720 186 21 , , PUNCT bjos-8674720 186 22 et et PROPN bjos-8674720 186 23     SPACE bjos-8674720 186 24 al al PROPN bjos-8674720 186 25 . . PUNCT bjos-8674720 187 1 vitamin vitamin PROPN bjos-8674720 187 2 c c PROPN bjos-8674720 187 3 promotes promote VERB bjos-8674720 187 4 wound wound ADJ bjos-8674720 187 5 healing healing NOUN bjos-8674720 187 6 through through ADP bjos-8674720 187 7 novel novel ADJ bjos-8674720 187 8 pleiotropic pleiotropic ADJ bjos-8674720 187 9 mechanisms mechanism NOUN bjos-8674720 187 10 . . PUNCT bjos-8674720 188 1 int int NOUN bjos-8674720 188 2 wound wound NOUN bjos-8674720 188 3 j. j. PROPN bjos-8674720 188 4 2016 2016 NUM bjos-8674720 188 5 aug;13(4):572 aug;13(4):572 PROPN bjos-8674720 188 6 - - NOUN bjos-8674720 188 7 84 84 NUM bjos-8674720 188 8 . . PUNCT bjos-8674720 189 1 doi doi NOUN bjos-8674720 189 2 : : PUNCT bjos-8674720 189 3 10.1111 10.1111 NUM bjos-8674720 189 4 / / SYM bjos-8674720 189 5 iwj.12484 iwj.12484 PROPN bjos-8674720 189 6 . . PUNCT bjos-8674720 190 1 epub epub PROPN bjos-8674720 190 2 2015 2015 NUM bjos-8674720 190 3 aug aug PROPN bjos-8674720 190 4 20 20 NUM bjos-8674720 190 5 . . PUNCT bjos-8674720 191 1 2 2 NUM bjos-8674720 191 2 . . X bjos-8674720 191 3 diegelmann diegelmann PROPN bjos-8674720 191 4 rf rf PROPN bjos-8674720 191 5 , , PUNCT bjos-8674720 191 6 evans evans PROPN bjos-8674720 191 7 mc mc PROPN bjos-8674720 191 8 . . PROPN bjos-8674720 191 9 wound wound PROPN bjos-8674720 191 10 healing healing NOUN bjos-8674720 191 11 : : PUNCT bjos-8674720 191 12 an an DET bjos-8674720 191 13 overview overview NOUN bjos-8674720 191 14 of of ADP bjos-8674720 191 15 acute acute NOUN bjos-8674720 191 16 , , PUNCT bjos-8674720 191 17 fibrotic fibrotic ADJ bjos-8674720 191 18 and and CCONJ bjos-8674720 191 19 delayed delayed ADJ bjos-8674720 191 20 healing healing NOUN bjos-8674720 191 21 . . PUNCT bjos-8674720 192 1 front front PROPN bjos-8674720 192 2 biosci biosci PROPN bjos-8674720 192 3 . . PUNCT bjos-8674720 193 1 2004 2004 NUM bjos-8674720 193 2 jan;9:283 jan;9:283 PROPN bjos-8674720 193 3 - - PUNCT bjos-8674720 193 4 9 9 NUM bjos-8674720 193 5 . . PUNCT bjos-8674720 193 6 doi doi NOUN bjos-8674720 193 7 : : PUNCT bjos-8674720 193 8 10.2741/1184 10.2741/1184 NUM bjos-8674720 193 9 . . NOUN bjos-8674720 194 1 3 3 NUM bjos-8674720 194 2 . . X bjos-8674720 194 3 dryden dryden PROPN bjos-8674720 194 4 sv sv PROPN bjos-8674720 194 5 , , PUNCT bjos-8674720 194 6 shoemaker shoemaker PROPN bjos-8674720 194 7 wg wg PROPN bjos-8674720 194 8 , , PUNCT bjos-8674720 194 9 kim kim PROPN bjos-8674720 194 10 jh jh PROPN bjos-8674720 194 11 . . PUNCT bjos-8674720 195 1 wound wound PROPN bjos-8674720 195 2 management management NOUN bjos-8674720 195 3 and and CCONJ bjos-8674720 195 4 nutrition nutrition NOUN bjos-8674720 195 5 for for ADP bjos-8674720 195 6 optimal optimal ADJ bjos-8674720 195 7 wound wound NOUN bjos-8674720 195 8 healing healing NOUN bjos-8674720 195 9 . . PUNCT bjos-8674720 196 1 atlas atlas PROPN bjos-8674720 196 2 oral oral ADJ bjos-8674720 196 3 maxillofac maxillofac NOUN bjos-8674720 196 4 surg surg NOUN bjos-8674720 196 5 clin clin PROPN bjos-8674720 196 6 north north PROPN bjos-8674720 196 7 am am PROPN bjos-8674720 196 8 . . PUNCT bjos-8674720 197 1 2013 2013 NUM bjos-8674720 197 2     SPACE bjos-8674720 197 3 mar;21(1):37 mar;21(1):37 PROPN bjos-8674720 197 4 - - PUNCT bjos-8674720 197 5 47 47 NUM bjos-8674720 197 6 . . PUNCT bjos-8674720 198 1 doi doi NOUN bjos-8674720 198 2 : : PUNCT bjos-8674720 198 3 10.1016 10.1016 NUM bjos-8674720 198 4 / / SYM bjos-8674720 198 5 j.cxom.2012.12.008 j.cxom.2012.12.008 PROPN bjos-8674720 198 6 . . PUNCT bjos-8674720 199 1 4 4 X bjos-8674720 199 2 . . X bjos-8674720 199 3 dale dale PROPN bjos-8674720 199 4 ba ba PROPN bjos-8674720 199 5 . . PUNCT bjos-8674720 200 1 periodontal periodontal ADJ bjos-8674720 200 2 epithelium epithelium NOUN bjos-8674720 200 3 : : PUNCT bjos-8674720 200 4 a a DET bjos-8674720 200 5 newly newly ADV bjos-8674720 200 6 recognized recognize VERB bjos-8674720 200 7 role role NOUN bjos-8674720 200 8 in in ADP bjos-8674720 200 9 health health NOUN bjos-8674720 200 10 and and CCONJ bjos-8674720 200 11 disease disease NOUN bjos-8674720 200 12 . . PUNCT bjos-8674720 201 1 periodontol periodontol NOUN bjos-8674720 201 2 2000 2000 NUM bjos-8674720 201 3 . . PUNCT bjos-8674720 202 1 2002;30:70 2002;30:70 NUM bjos-8674720 202 2 - - SYM bjos-8674720 202 3 8 8 NUM bjos-8674720 202 4 . . PUNCT bjos-8674720 202 5 doi doi NOUN bjos-8674720 202 6 : : PUNCT bjos-8674720 202 7 10.1034 10.1034 NUM bjos-8674720 202 8 / / SYM bjos-8674720 202 9 j.1600 j.1600 NOUN bjos-8674720 202 10 - - PUNCT bjos-8674720 202 11 0757.2002.03007.x 0757.2002.03007.x NOUN bjos-8674720 202 12 . . PROPN bjos-8674720 203 1 5 5 NUM bjos-8674720 203 2 . . X bjos-8674720 203 3 sedghi sedghi VERB bjos-8674720 203 4 l l NOUN bjos-8674720 203 5 , , PUNCT bjos-8674720 203 6 dimassa dimassa NOUN bjos-8674720 203 7 v v NOUN bjos-8674720 203 8 , , PUNCT bjos-8674720 203 9 harrington harrington PROPN bjos-8674720 203 10 a a PROPN bjos-8674720 203 11 , , PUNCT bjos-8674720 203 12 lynch lynch PROPN bjos-8674720 203 13 sv sv PROPN bjos-8674720 203 14 , , PUNCT bjos-8674720 203 15 kapila kapila PROPN bjos-8674720 203 16 yl yl NOUN bjos-8674720 203 17 . . PUNCT bjos-8674720 204 1 the the DET bjos-8674720 204 2 oral oral ADJ bjos-8674720 204 3 microbiome microbiome NOUN bjos-8674720 204 4 : : PUNCT bjos-8674720 204 5 role role NOUN bjos-8674720 204 6 of of ADP bjos-8674720 204 7 key key ADJ bjos-8674720 204 8 organisms organism NOUN bjos-8674720 204 9 and and CCONJ bjos-8674720 204 10 complex complex ADJ bjos-8674720 204 11 networks network NOUN bjos-8674720 204 12 in in ADP bjos-8674720 204 13 oral oral ADJ bjos-8674720 204 14 health health NOUN bjos-8674720 204 15 and and CCONJ bjos-8674720 204 16 disease disease NOUN bjos-8674720 204 17 . . PUNCT bjos-8674720 205 1 periodontol periodontol NOUN bjos-8674720 205 2 2000 2000 NUM bjos-8674720 205 3 . . PUNCT bjos-8674720 206 1 2021 2021 NUM bjos-8674720 206 2 oct;87(1):107 oct;87(1):107 NUM bjos-8674720 206 3 - - SYM bjos-8674720 206 4 31 31 NUM bjos-8674720 206 5 . . PUNCT bjos-8674720 207 1 doi doi NOUN bjos-8674720 207 2 : : PUNCT bjos-8674720 207 3 10.1111 10.1111 NUM bjos-8674720 207 4 / / SYM bjos-8674720 207 5 prd.12393 prd.12393 NOUN bjos-8674720 207 6 . . PUNCT bjos-8674720 208 1 10 10 NUM bjos-8674720 208 2 mendes mende NOUN bjos-8674720 208 3 et et PROPN bjos-8674720 208 4 al al PROPN bjos-8674720 208 5 . . PROPN bjos-8674720 208 6 braz braz PROPN bjos-8674720 208 7 j j PROPN bjos-8674720 208 8 oral oral PROPN bjos-8674720 208 9 sci sci PROPN bjos-8674720 208 10 . . PUNCT bjos-8674720 209 1 2024;23 2024;23 NUM bjos-8674720 209 2 : : PUNCT bjos-8674720 209 3 e244720 e244720 NOUN bjos-8674720 209 4 6 6 NUM bjos-8674720 209 5 . . PUNCT bjos-8674720 210 1 xu xu PROPN bjos-8674720 211 1 w w PROPN bjos-8674720 211 2 , , PUNCT bjos-8674720 211 3 zhou zhou PROPN bjos-8674720 211 4 w w PROPN bjos-8674720 211 5 , , PUNCT bjos-8674720 211 6 wang wang PROPN bjos-8674720 211 7 h h PROPN bjos-8674720 211 8 , , PUNCT bjos-8674720 211 9 liang liang PROPN bjos-8674720 211 10 s. s. PROPN bjos-8674720 211 11 roles role NOUN bjos-8674720 211 12 of of ADP bjos-8674720 211 13 porphyromonas porphyromona NOUN bjos-8674720 211 14 gingivalis gingivalis PROPN bjos-8674720 211 15 and and CCONJ bjos-8674720 211 16 its its PRON bjos-8674720 211 17 virulence virulence NOUN bjos-8674720 211 18 factors factor NOUN bjos-8674720 211 19 in in ADP bjos-8674720 211 20 periodontitis periodontitis NOUN bjos-8674720 211 21 . . PUNCT bjos-8674720 212 1 adv adv PROPN bjos-8674720 212 2 protein protein NOUN bjos-8674720 212 3 chem chem NOUN bjos-8674720 212 4 struct struct NOUN bjos-8674720 212 5 biol biol NOUN bjos-8674720 212 6 . . PUNCT bjos-8674720 213 1 2020;120:45 2020;120:45 NUM bjos-8674720 213 2 - - SYM bjos-8674720 213 3 84 84 NUM bjos-8674720 213 4 . . PUNCT bjos-8674720 214 1 doi doi NOUN bjos-8674720 214 2 : : PUNCT bjos-8674720 214 3 10.1016 10.1016 NUM bjos-8674720 214 4 / / SYM bjos-8674720 214 5 bs.apcsb.2019.12.001 bs.apcsb.2019.12.001 PROPN bjos-8674720 214 6 . . PUNCT bjos-8674720 215 1 7 7 X bjos-8674720 215 2 . . X bjos-8674720 215 3 haraguchi haraguchi PROPN bjos-8674720 215 4 a a NOUN bjos-8674720 215 5 , , PUNCT bjos-8674720 215 6 miura miura PROPN bjos-8674720 215 7 m m PROPN bjos-8674720 215 8 , , PUNCT bjos-8674720 215 9 fujise fujise NOUN bjos-8674720 215 10 o o NOUN bjos-8674720 215 11 , , PUNCT bjos-8674720 215 12 hamachi hamachi PROPN bjos-8674720 215 13 t t PROPN bjos-8674720 215 14 , , PUNCT bjos-8674720 215 15 nishimura nishimura PROPN bjos-8674720 215 16 f. f. PROPN bjos-8674720 215 17 porphyromonas porphyromonas PROPN bjos-8674720 215 18 gingivalis gingivalis PROPN bjos-8674720 215 19 gingipain gingipain PROPN bjos-8674720 215 20 is be AUX bjos-8674720 215 21 involved involve VERB bjos-8674720 215 22 in in ADP bjos-8674720 215 23 the the DET bjos-8674720 215 24 detachment detachment NOUN bjos-8674720 215 25 and and CCONJ bjos-8674720 215 26 aggregation aggregation NOUN bjos-8674720 215 27 of of ADP bjos-8674720 215 28 aggregatibacter aggregatibacter PROPN bjos-8674720 215 29 actinomycetemcomitans actinomycetemcomitans PROPN bjos-8674720 215 30 biofilm biofilm NOUN bjos-8674720 215 31 . . PUNCT bjos-8674720 216 1 mol mol ADP bjos-8674720 216 2 oral oral ADJ bjos-8674720 216 3 microbiol microbiol NOUN bjos-8674720 216 4 . . PUNCT bjos-8674720 217 1 2014 2014 NUM bjos-8674720 217 2 jun;29(3):131 jun;29(3):131 PROPN bjos-8674720 217 3 - - SYM bjos-8674720 217 4 43 43 NUM bjos-8674720 217 5 . . PUNCT bjos-8674720 218 1 doi doi NOUN bjos-8674720 218 2 : : PUNCT bjos-8674720 218 3 10.1111 10.1111 NUM bjos-8674720 218 4 / / SYM bjos-8674720 218 5 omi.12051 omi.12051 NUM bjos-8674720 218 6 . . NOUN bjos-8674720 218 7 8 8 NUM bjos-8674720 218 8 . . PUNCT bjos-8674720 219 1 bhattacharya bhattacharya PROPN bjos-8674720 219 2 r r PROPN bjos-8674720 219 3 , , PUNCT bjos-8674720 219 4 xu xu PROPN bjos-8674720 220 1 f f PROPN bjos-8674720 220 2 , , PUNCT bjos-8674720 220 3 dong dong PROPN bjos-8674720 220 4 g g PROPN bjos-8674720 220 5 , , PUNCT bjos-8674720 220 6 li li PROPN bjos-8674720 220 7 s s PROPN bjos-8674720 220 8 , , PUNCT bjos-8674720 220 9 tian tian PROPN bjos-8674720 220 10 c c X bjos-8674720 220 11 , , PUNCT bjos-8674720 220 12 ponugoti ponugoti PROPN bjos-8674720 220 13 b b PROPN bjos-8674720 220 14 , , PUNCT bjos-8674720 220 15 et et PROPN bjos-8674720 220 16     SPACE bjos-8674720 220 17 al al PROPN bjos-8674720 220 18 . . PROPN bjos-8674720 220 19 effect effect NOUN bjos-8674720 220 20 of of ADP bjos-8674720 220 21 bacteria bacteria NOUN bjos-8674720 220 22 on on ADP bjos-8674720 220 23 the the DET bjos-8674720 220 24 wound wound NOUN bjos-8674720 220 25 healing heal VERB bjos-8674720 220 26 behavior behavior NOUN bjos-8674720 220 27 of of ADP bjos-8674720 220 28 oral oral ADJ bjos-8674720 220 29 epithelial epithelial ADJ bjos-8674720 220 30 cells cell NOUN bjos-8674720 220 31 . . PUNCT bjos-8674720 221 1 plos plos PROPN bjos-8674720 221 2 one one NUM bjos-8674720 221 3 . . PUNCT bjos-8674720 222 1 2014 2014 NUM bjos-8674720 222 2 feb;9(2):e89475 feb;9(2):e89475 NOUN bjos-8674720 222 3 . . PUNCT bjos-8674720 222 4 doi doi NOUN bjos-8674720 222 5 : : PUNCT bjos-8674720 222 6 10.1371 10.1371 NUM bjos-8674720 222 7 / / SYM bjos-8674720 222 8 journal.pone.0089475 journal.pone.0089475 PROPN bjos-8674720 222 9 . . PROPN bjos-8674720 223 1 9 9 NUM bjos-8674720 223 2 . . X bjos-8674720 224 1 zhang zhang PROPN bjos-8674720 224 2 l l PROPN bjos-8674720 224 3 , , PUNCT bjos-8674720 224 4 pelech pelech NOUN bjos-8674720 224 5 sl sl NOUN bjos-8674720 224 6 , , PUNCT bjos-8674720 224 7 mayrand mayrand PROPN bjos-8674720 224 8 d d PROPN bjos-8674720 224 9 , , PUNCT bjos-8674720 224 10 grenier grenier PROPN bjos-8674720 224 11 d d PROPN bjos-8674720 224 12 , , PUNCT bjos-8674720 224 13 heino heino PROPN bjos-8674720 224 14 j j PROPN bjos-8674720 224 15 , , PUNCT bjos-8674720 224 16 uitto uitto ADJ bjos-8674720 224 17 vj vj PROPN bjos-8674720 224 18 . . PROPN bjos-8674720 225 1 bacterial bacterial ADJ bjos-8674720 225 2 heat heat NOUN bjos-8674720 225 3 shock shock NOUN bjos-8674720 225 4 protein-60 protein-60 PROPN bjos-8674720 225 5 increases increase VERB bjos-8674720 225 6 epithelial epithelial ADJ bjos-8674720 225 7 cell cell NOUN bjos-8674720 225 8 proliferation proliferation NOUN bjos-8674720 225 9 through through ADP bjos-8674720 225 10 the the DET bjos-8674720 225 11 erk1/2 erk1/2 PROPN bjos-8674720 225 12 map map NOUN bjos-8674720 225 13 kinases kinase NOUN bjos-8674720 225 14 . . PUNCT bjos-8674720 226 1 exp exp NOUN bjos-8674720 226 2 cell cell NOUN bjos-8674720 226 3 res re NOUN bjos-8674720 226 4 . . PUNCT bjos-8674720 227 1 2001 2001 NUM bjos-8674720 227 2     SPACE bjos-8674720 227 3 may;266(1):11 may;266(1):11 PROPN bjos-8674720 227 4 - - PUNCT bjos-8674720 227 5 20 20 NUM bjos-8674720 227 6 . . PUNCT bjos-8674720 228 1 doi doi NOUN bjos-8674720 228 2 : : PUNCT bjos-8674720 228 3 10.1006 10.1006 NUM bjos-8674720 228 4 / / SYM bjos-8674720 228 5 excr.2001.5199 excr.2001.5199 NOUN bjos-8674720 228 6 . . NOUN bjos-8674720 229 1 10 10 NUM bjos-8674720 229 2 . . PUNCT bjos-8674720 229 3 smith smith PROPN bjos-8674720 229 4 jl jl PROPN bjos-8674720 229 5 , , PUNCT bjos-8674720 229 6 bayles bayle NOUN bjos-8674720 229 7 do do VERB bjos-8674720 229 8 . . PUNCT bjos-8674720 230 1 the the DET bjos-8674720 230 2 contribution contribution NOUN bjos-8674720 230 3 of of ADP bjos-8674720 230 4 cytolethal cytolethal ADJ bjos-8674720 230 5 distending distend VERB bjos-8674720 230 6 toxin toxin NOUN bjos-8674720 230 7 to to ADP bjos-8674720 230 8 bacterial bacterial ADJ bjos-8674720 230 9 pathogenesis pathogenesis NOUN bjos-8674720 230 10 . . PUNCT bjos-8674720 231 1 crit crit PROPN bjos-8674720 231 2 rev rev PROPN bjos-8674720 231 3 microbiol microbiol PROPN bjos-8674720 231 4 . . PUNCT bjos-8674720 232 1 2006 2006 NUM bjos-8674720 232 2 oct oct NOUN bjos-8674720 232 3 - - PUNCT bjos-8674720 232 4 dec;32(4):227 dec;32(4):227 PROPN bjos-8674720 232 5 - - PUNCT bjos-8674720 232 6 48 48 NUM bjos-8674720 232 7 . . PUNCT bjos-8674720 233 1 doi doi NOUN bjos-8674720 233 2 : : PUNCT bjos-8674720 233 3 10.1080/10408410601023557 10.1080/10408410601023557 NUM bjos-8674720 233 4 . . PUNCT bjos-8674720 234 1 11 11 NUM bjos-8674720 234 2 . . PUNCT bjos-8674720 235 1 silveira silveira PROPN bjos-8674720 235 2 vr vr PROPN bjos-8674720 235 3 , , PUNCT bjos-8674720 235 4 nogueira nogueira PROPN bjos-8674720 235 5 mv mv PROPN bjos-8674720 235 6 , , PUNCT bjos-8674720 235 7 nogueira nogueira PROPN bjos-8674720 235 8 na na PROPN bjos-8674720 235 9 , , PUNCT bjos-8674720 235 10 lima lima PROPN bjos-8674720 235 11 v v NOUN bjos-8674720 235 12 , , PUNCT bjos-8674720 235 13 furlaneto furlaneto PROPN bjos-8674720 235 14 fa fa PROPN bjos-8674720 235 15 , , PUNCT bjos-8674720 235 16 rego rego PROPN bjos-8674720 235 17 ro ro PROPN bjos-8674720 235 18 . . PROPN bjos-8674720 236 1 leukotoxicity leukotoxicity PROPN bjos-8674720 236 2 of of ADP bjos-8674720 236 3 aggregatibacter aggregatibacter NOUN bjos-8674720 236 4 actinomycetemcomitans actinomycetemcomitan NOUN bjos-8674720 236 5 in in ADP bjos-8674720 236 6 generalized generalized ADJ bjos-8674720 236 7 aggressive aggressive ADJ bjos-8674720 236 8 periodontitis periodontitis NOUN bjos-8674720 236 9 in in ADP bjos-8674720 236 10 brazilians brazilians PROPN bjos-8674720 236 11 and and CCONJ bjos-8674720 236 12 their their PRON bjos-8674720 236 13 family family NOUN bjos-8674720 236 14 members member NOUN bjos-8674720 236 15 . . PUNCT bjos-8674720 237 1 j j PROPN bjos-8674720 237 2 appl appl PROPN bjos-8674720 237 3 oral oral PROPN bjos-8674720 237 4 sci sci PROPN bjos-8674720 237 5 . . PROPN bjos-8674720 238 1 2013 2013 NUM bjos-8674720 238 2 sep sep PROPN bjos-8674720 238 3 - - PUNCT bjos-8674720 238 4 oct;21(5):430 oct;21(5):430 PROPN bjos-8674720 238 5 - - PUNCT bjos-8674720 238 6 6 6 NUM bjos-8674720 238 7 . . PUNCT bjos-8674720 238 8 doi doi NOUN bjos-8674720 238 9 : : PUNCT bjos-8674720 238 10 10.1590/1679 10.1590/1679 NUM bjos-8674720 238 11 - - SYM bjos-8674720 238 12 775720130252 775720130252 NUM bjos-8674720 238 13 . . PUNCT bjos-8674720 239 1 12 12 NUM bjos-8674720 239 2 . . PUNCT bjos-8674720 240 1 stolf stolf PROPN bjos-8674720 240 2 cs cs PROPN bjos-8674720 240 3 , , PUNCT bjos-8674720 240 4 sacramento sacramento PROPN bjos-8674720 240 5 cm cm PROPN bjos-8674720 240 6 , , PUNCT bjos-8674720 240 7 alvarenga alvarenga NOUN bjos-8674720 240 8 capg capg PROPN bjos-8674720 240 9 , , PUNCT bjos-8674720 240 10 vieira vieira PROPN bjos-8674720 240 11 jr jr PROPN bjos-8674720 240 12 , , PUNCT bjos-8674720 240 13 araújo araújo PROPN bjos-8674720 240 14 cf cf NOUN bjos-8674720 240 15 , , PUNCT bjos-8674720 240 16 monteiro monteiro PROPN bjos-8674720 240 17 mf mf PROPN bjos-8674720 240 18 , , PUNCT bjos-8674720 240 19 et et PROPN bjos-8674720 240 20     SPACE bjos-8674720 240 21 al al PROPN bjos-8674720 240 22 . . PROPN bjos-8674720 240 23 immune immune ADJ bjos-8674720 240 24 response response NOUN bjos-8674720 240 25 characterization characterization NOUN bjos-8674720 240 26 of of ADP bjos-8674720 240 27 primary primary ADJ bjos-8674720 240 28 gingival gingival NOUN bjos-8674720 240 29 fibroblasts fibroblast NOUN bjos-8674720 240 30 from from ADP bjos-8674720 240 31 grade grade NOUN bjos-8674720 240 32 c c NOUN bjos-8674720 240 33 periodontitis periodontitis NOUN bjos-8674720 240 34 patients patient NOUN bjos-8674720 240 35 . . PUNCT bjos-8674720 241 1 j j PROPN bjos-8674720 241 2 periodontol periodontol NOUN bjos-8674720 241 3 . . PUNCT bjos-8674720 242 1 2023 2023 NUM bjos-8674720 242 2     SPACE bjos-8674720 242 3 mar;94(3):429 mar;94(3):429 PROPN bjos-8674720 242 4 - - PUNCT bjos-8674720 242 5 38 38 NUM bjos-8674720 242 6 . . PUNCT bjos-8674720 243 1 doi doi NOUN bjos-8674720 243 2 : : PUNCT bjos-8674720 243 3 10.1002 10.1002 NUM bjos-8674720 243 4 / / SYM bjos-8674720 243 5 jper.22 jper.22 NOUN bjos-8674720 243 6 - - PUNCT bjos-8674720 243 7 0356 0356 NUM bjos-8674720 243 8 . . PUNCT bjos-8674720 244 1 epub epub NOUN bjos-8674720 244 2 2022 2022 NUM bjos-8674720 244 3 nov nov PROPN bjos-8674720 244 4 15 15 NUM bjos-8674720 244 5 . . PROPN bjos-8674720 244 6 13 13 NUM bjos-8674720 244 7 . . PUNCT bjos-8674720 245 1 albuquerque albuquerque PROPN bjos-8674720 245 2 - - PUNCT bjos-8674720 245 3 souza souza PROPN bjos-8674720 245 4 e e PROPN bjos-8674720 245 5 , , PUNCT bjos-8674720 245 6 ishikawa ishikawa PROPN bjos-8674720 245 7 kh kh PROPN bjos-8674720 245 8 , , PUNCT bjos-8674720 245 9 amado amado ADJ bjos-8674720 245 10 pp pp PROPN bjos-8674720 245 11 , , PUNCT bjos-8674720 245 12 nicoli nicoli PROPN bjos-8674720 245 13 jr jr PROPN bjos-8674720 245 14 , , PUNCT bjos-8674720 245 15 holzhausen holzhausen PROPN bjos-8674720 245 16 m m PROPN bjos-8674720 245 17 , , PUNCT bjos-8674720 245 18 mayer mayer PROPN bjos-8674720 245 19 mpa mpa PROPN bjos-8674720 245 20 . . PUNCT bjos-8674720 246 1 probiotics probiotic NOUN bjos-8674720 246 2 improve improve VERB bjos-8674720 246 3 re re NOUN bjos-8674720 246 4 - - NOUN bjos-8674720 246 5 epithelialization epithelialization NOUN bjos-8674720 246 6 of of ADP bjos-8674720 246 7 scratches scratch NOUN bjos-8674720 246 8 infected infect VERB bjos-8674720 246 9 by by ADP bjos-8674720 246 10 porphyromonas porphyromona NOUN bjos-8674720 246 11 gingivalis gingivali VERB bjos-8674720 246 12 through through ADP bjos-8674720 246 13 up up ADV bjos-8674720 246 14 - - PUNCT bjos-8674720 246 15 regulating regulate VERB bjos-8674720 246 16 cxcl8 cxcl8 NOUN bjos-8674720 246 17 - - PUNCT bjos-8674720 246 18 cxcr1 cxcr1 NOUN bjos-8674720 246 19 / / SYM bjos-8674720 246 20 cxcr2 cxcr2 NOUN bjos-8674720 246 21 axis axis NOUN bjos-8674720 246 22 . . PUNCT bjos-8674720 247 1 anaerobe anaerobe NOUN bjos-8674720 247 2 . . PUNCT bjos-8674720 248 1 2021 2021 NUM bjos-8674720 248 2 dec;72:102458 dec;72:102458 ADJ bjos-8674720 248 3 . . PUNCT bjos-8674720 249 1 doi doi NOUN bjos-8674720 249 2 : : PUNCT bjos-8674720 249 3 10.1016 10.1016 NUM bjos-8674720 249 4 / / SYM bjos-8674720 249 5 j.anaerobe.2021.102458 j.anaerobe.2021.102458 ADJ bjos-8674720 249 6 . . PUNCT bjos-8674720 250 1 14 14 NUM bjos-8674720 250 2 . . PUNCT bjos-8674720 251 1 lamont lamont PROPN bjos-8674720 251 2 rj rj PROPN bjos-8674720 251 3 , , PUNCT bjos-8674720 251 4 koo koo PROPN bjos-8674720 251 5 h h PROPN bjos-8674720 251 6 , , PUNCT bjos-8674720 251 7 hajishengallis hajishengallis PROPN bjos-8674720 251 8 g. g. VERB bjos-8674720 251 9 the the DET bjos-8674720 251 10 oral oral ADJ bjos-8674720 251 11 microbiota microbiota NOUN bjos-8674720 251 12 : : PUNCT bjos-8674720 251 13 dynamic dynamic ADJ bjos-8674720 251 14 communities community NOUN bjos-8674720 251 15 and and CCONJ bjos-8674720 251 16 host host NOUN bjos-8674720 251 17 interactions interaction NOUN bjos-8674720 251 18 . . PUNCT bjos-8674720 252 1 nat nat PROPN bjos-8674720 252 2 rev rev PROPN bjos-8674720 252 3 microbiol microbiol PROPN bjos-8674720 252 4 . . PUNCT bjos-8674720 253 1 2018 2018 NUM bjos-8674720 253 2 dec;16(12):745 dec;16(12):745 PROPN bjos-8674720 253 3 - - PUNCT bjos-8674720 253 4 59 59 NUM bjos-8674720 253 5 . . PUNCT bjos-8674720 253 6 doi doi NOUN bjos-8674720 253 7 : : PUNCT bjos-8674720 253 8 10.1038 10.1038 NUM bjos-8674720 253 9 / / SYM bjos-8674720 253 10 s41579 s41579 NOUN bjos-8674720 253 11 - - PUNCT bjos-8674720 253 12 018 018 NUM bjos-8674720 253 13 - - PUNCT bjos-8674720 253 14 0089 0089 NUM bjos-8674720 253 15 - - PUNCT bjos-8674720 253 16 x. x. NOUN bjos-8674720 253 17 15 15 NUM bjos-8674720 253 18 . . PUNCT bjos-8674720 253 19 chaitrakoonthong chaitrakoonthong PROPN bjos-8674720 253 20 t t PROPN bjos-8674720 253 21 , , PUNCT bjos-8674720 253 22 ampornaramveth ampornaramveth PROPN bjos-8674720 253 23 r r PROPN bjos-8674720 253 24 , , PUNCT bjos-8674720 253 25 kamolratanakul kamolratanakul ADJ bjos-8674720 253 26 p. p. NOUN bjos-8674720 253 27 rinsing rinsing NOUN bjos-8674720 253 28 with with ADP bjos-8674720 253 29 l l ADJ bjos-8674720 253 30 - - ADJ bjos-8674720 253 31 ascorbic ascorbic ADJ bjos-8674720 253 32 acid acid NOUN bjos-8674720 253 33 exhibits exhibit VERB bjos-8674720 253 34 concentration concentration NOUN bjos-8674720 253 35 - - PUNCT bjos-8674720 253 36 dependent dependent ADJ bjos-8674720 253 37 effects effect NOUN bjos-8674720 253 38 on on ADP bjos-8674720 253 39 human human ADJ bjos-8674720 253 40 gingival gingival NOUN bjos-8674720 253 41 fibroblast fibroblast NOUN bjos-8674720 253 42 in in ADP bjos-8674720 253 43 vitro vitro X bjos-8674720 253 44 wound wound ADJ bjos-8674720 253 45 healing healing NOUN bjos-8674720 253 46 behavior behavior NOUN bjos-8674720 253 47 . . PUNCT bjos-8674720 254 1 int int PROPN bjos-8674720 254 2 j j PROPN bjos-8674720 254 3 dent dent NOUN bjos-8674720 254 4 . . PUNCT bjos-8674720 255 1 2020 2020 NUM bjos-8674720 255 2     SPACE bjos-8674720 255 3 mar;2020:4706418 mar;2020:4706418 PROPN bjos-8674720 255 4 . . PUNCT bjos-8674720 256 1 doi doi NOUN bjos-8674720 256 2 : : PUNCT bjos-8674720 256 3 10.1155/2020/4706418 10.1155/2020/4706418 NUM bjos-8674720 256 4 . . NOUN bjos-8674720 256 5 16 16 NUM bjos-8674720 256 6 . . PUNCT bjos-8674720 257 1 xiao xiao PROPN bjos-8674720 257 2 l l PROPN bjos-8674720 257 3 , , PUNCT bjos-8674720 257 4 miwa miwa PROPN bjos-8674720 257 5 n. n. PROPN bjos-8674720 257 6 hydrogen hydrogen PROPN bjos-8674720 257 7 - - PUNCT bjos-8674720 257 8 rich rich ADJ bjos-8674720 257 9 water water NOUN bjos-8674720 257 10 achieves achieve VERB bjos-8674720 257 11 cytoprotection cytoprotection NOUN bjos-8674720 257 12 from from ADP bjos-8674720 257 13 oxidative oxidative ADJ bjos-8674720 257 14 stress stress NOUN bjos-8674720 257 15 injury injury NOUN bjos-8674720 257 16 in in ADP bjos-8674720 257 17 human human ADJ bjos-8674720 257 18 gingival gingival NOUN bjos-8674720 257 19 fibroblasts fibroblast NOUN bjos-8674720 257 20 in in ADP bjos-8674720 257 21 culture culture NOUN bjos-8674720 257 22 or or CCONJ bjos-8674720 257 23 3d 3d NUM bjos-8674720 257 24 - - PUNCT bjos-8674720 257 25 tissue tissue NOUN bjos-8674720 257 26 equivalents equivalent NOUN bjos-8674720 257 27 , , PUNCT bjos-8674720 257 28 and and CCONJ bjos-8674720 257 29 wound wound NOUN bjos-8674720 257 30 - - PUNCT bjos-8674720 257 31 healing healing NOUN bjos-8674720 257 32 promotion promotion NOUN bjos-8674720 257 33 , , PUNCT bjos-8674720 257 34 together together ADV bjos-8674720 257 35 with with ADP bjos-8674720 257 36 ros ros PROPN bjos-8674720 257 37 - - PUNCT bjos-8674720 257 38 scavenging scavenge VERB bjos-8674720 257 39 and and CCONJ bjos-8674720 257 40 relief relief NOUN bjos-8674720 257 41 from from ADP bjos-8674720 257 42 glutathione glutathione NOUN bjos-8674720 257 43 diminishment diminishment NOUN bjos-8674720 257 44 . . PUNCT bjos-8674720 258 1 hum hum ADJ bjos-8674720 258 2 cell cell NOUN bjos-8674720 258 3 . . PUNCT bjos-8674720 259 1 2017 2017 NUM bjos-8674720 259 2 apr;30(2):72 apr;30(2):72 NOUN bjos-8674720 259 3 - - PUNCT bjos-8674720 259 4 87 87 NUM bjos-8674720 259 5 . . PUNCT bjos-8674720 260 1 doi doi NOUN bjos-8674720 260 2 : : PUNCT bjos-8674720 260 3 10.1007 10.1007 NUM bjos-8674720 260 4 / / SYM bjos-8674720 260 5 s13577 s13577 PROPN bjos-8674720 260 6 - - PUNCT bjos-8674720 260 7 016 016 NUM bjos-8674720 260 8 - - PUNCT bjos-8674720 260 9 0150 0150 NUM bjos-8674720 260 10 - - PUNCT bjos-8674720 260 11 x. x. NOUN bjos-8674720 260 12 epub epub PROPN bjos-8674720 260 13 2016 2016 NUM bjos-8674720 260 14 nov nov PROPN bjos-8674720 260 15 1 1 NUM bjos-8674720 260 16 . . PROPN bjos-8674720 260 17 17 17 NUM bjos-8674720 260 18 . . PUNCT bjos-8674720 261 1 bikker bikker PROPN bjos-8674720 261 2 a a PROPN bjos-8674720 261 3 , , PUNCT bjos-8674720 261 4 wielders wielders PROPN bjos-8674720 261 5 j j PROPN bjos-8674720 261 6 , , PUNCT bjos-8674720 261 7 loo loo PROPN bjos-8674720 261 8 rv rv PROPN bjos-8674720 261 9 , , PUNCT bjos-8674720 261 10 loubert loubert PROPN bjos-8674720 261 11 m. m. NOUN bjos-8674720 261 12 ascorbic ascorbic NOUN bjos-8674720 261 13 acid acid NOUN bjos-8674720 261 14 deficiency deficiency NOUN bjos-8674720 261 15 impairs impair VERB bjos-8674720 261 16 wound wound ADJ bjos-8674720 261 17 healing healing NOUN bjos-8674720 261 18 in in ADP bjos-8674720 261 19 surgical surgical ADJ bjos-8674720 261 20 patients patient NOUN bjos-8674720 261 21 : : PUNCT bjos-8674720 261 22 four four NUM bjos-8674720 261 23 case case NOUN bjos-8674720 261 24 reports report VERB bjos-8674720 261 25 . . PUNCT bjos-8674720 262 1 int int PROPN bjos-8674720 262 2 j j PROPN bjos-8674720 262 3 surg surg PROPN bjos-8674720 262 4 open open VERB bjos-8674720 262 5 2016;2:15 2016;2:15 NOUN bjos-8674720 262 6 - - SYM bjos-8674720 262 7 8 8 NUM bjos-8674720 262 8 . . PUNCT bjos-8674720 263 1 doi doi NOUN bjos-8674720 263 2 : : PUNCT bjos-8674720 263 3 10.1016 10.1016 NUM bjos-8674720 263 4 / / SYM bjos-8674720 263 5 j.ijso.2016.02.009 j.ijso.2016.02.009 PROPN bjos-8674720 263 6 . . PROPN bjos-8674720 264 1 18 18 NUM bjos-8674720 264 2 . . PUNCT bjos-8674720 265 1 weinreb weinreb PROPN bjos-8674720 265 2 m m PROPN bjos-8674720 265 3 , , PUNCT bjos-8674720 265 4 nemcovsky nemcovsky PROPN bjos-8674720 265 5 ce ce PROPN bjos-8674720 265 6 . . PUNCT bjos-8674720 266 1 in in ADP bjos-8674720 266 2 vitro vitro X bjos-8674720 266 3 models model NOUN bjos-8674720 266 4 for for ADP bjos-8674720 266 5 evaluation evaluation NOUN bjos-8674720 266 6 of of ADP bjos-8674720 266 7 periodontal periodontal ADJ bjos-8674720 266 8 wound wound NOUN bjos-8674720 266 9 healing healing NOUN bjos-8674720 266 10 / / SYM bjos-8674720 266 11 regeneration regeneration NOUN bjos-8674720 266 12 . . PUNCT bjos-8674720 267 1 periodontol periodontol NOUN bjos-8674720 267 2 2000 2000 NUM bjos-8674720 267 3 . . PUNCT bjos-8674720 268 1 2015 2015 NUM bjos-8674720 268 2 jun;68(1):41 jun;68(1):41 PROPN bjos-8674720 268 3 - - SYM bjos-8674720 268 4 54 54 NUM bjos-8674720 268 5 . . PUNCT bjos-8674720 269 1 doi doi NOUN bjos-8674720 269 2 : : PUNCT bjos-8674720 269 3 10.1111 10.1111 NUM bjos-8674720 269 4 / / SYM bjos-8674720 269 5 prd.12079 prd.12079 NOUN bjos-8674720 269 6 . . PROPN bjos-8674720 270 1 19 19 NUM bjos-8674720 270 2 . . PUNCT bjos-8674720 271 1 kongkadee kongkadee PROPN bjos-8674720 271 2 k k PROPN bjos-8674720 271 3 , , PUNCT bjos-8674720 271 4 wisuitiprot wisuitiprot PROPN bjos-8674720 271 5 w w PROPN bjos-8674720 271 6 , , PUNCT bjos-8674720 271 7 ingkaninan ingkaninan PROPN bjos-8674720 271 8 k k NOUN bjos-8674720 271 9 , , PUNCT bjos-8674720 271 10 waranuch waranuch PROPN bjos-8674720 271 11 n. n. PROPN bjos-8674720 271 12 anti anti ADJ bjos-8674720 271 13 - - ADJ bjos-8674720 271 14 inflammation inflammation ADJ bjos-8674720 271 15 and and CCONJ bjos-8674720 271 16 gingival gingival NOUN bjos-8674720 271 17 wound wound NOUN bjos-8674720 271 18 healing healing NOUN bjos-8674720 271 19 activities activity NOUN bjos-8674720 271 20 of of ADP bjos-8674720 271 21 cannabis cannabis NOUN bjos-8674720 271 22 sativa sativa NOUN bjos-8674720 271 23 l. l. PROPN bjos-8674720 271 24 subsp subsp PROPN bjos-8674720 271 25 . . PUNCT bjos-8674720 272 1 sativa sativa NOUN bjos-8674720 272 2 ( ( PUNCT bjos-8674720 272 3 hemp hemp NOUN bjos-8674720 272 4 ) ) PUNCT bjos-8674720 272 5 extract extract NOUN bjos-8674720 272 6 and and CCONJ bjos-8674720 272 7 cannabidiol cannabidiol NOUN bjos-8674720 272 8 : : PUNCT bjos-8674720 272 9 an an DET bjos-8674720 272 10 in in ADP bjos-8674720 272 11 vitro vitro X bjos-8674720 272 12 study study NOUN bjos-8674720 272 13 . . PUNCT bjos-8674720 273 1 arch arch ADJ bjos-8674720 273 2 oral oral ADJ bjos-8674720 273 3 biol biol NOUN bjos-8674720 273 4 . . PUNCT bjos-8674720 274 1 2022 2022 NUM bjos-8674720 274 2 aug;140:105464 aug;140:105464 ADP bjos-8674720 274 3 . . PUNCT bjos-8674720 275 1 doi doi NOUN bjos-8674720 275 2 : : PUNCT bjos-8674720 275 3 10.1016 10.1016 NUM bjos-8674720 275 4 / / SYM bjos-8674720 275 5 j.archoralbio.2022.105464 j.archoralbio.2022.105464 NOUN bjos-8674720 275 6 . . PROPN bjos-8674720 276 1 20 20 NUM bjos-8674720 276 2 . . X bjos-8674720 277 1 mohammedsaeed mohammedsaeed PROPN bjos-8674720 277 2 w w PROPN bjos-8674720 277 3 , , PUNCT bjos-8674720 277 4 cruickshank cruickshank PROPN bjos-8674720 277 5 s s PROPN bjos-8674720 277 6 , , PUNCT bjos-8674720 277 7 mcbain mcbain PROPN bjos-8674720 277 8 aj aj PROPN bjos-8674720 277 9 , , PUNCT bjos-8674720 277 10 o’neill o’neill PROPN bjos-8674720 277 11 ca ca NOUN bjos-8674720 277 12 . . PUNCT bjos-8674720 278 1 lactobacillus lactobacillus PROPN bjos-8674720 278 2 rhamnosus rhamnosus PROPN bjos-8674720 278 3 gg gg PROPN bjos-8674720 278 4 lysate lysate NOUN bjos-8674720 278 5 increases increase VERB bjos-8674720 278 6 re re NOUN bjos-8674720 278 7 - - NOUN bjos-8674720 278 8 epithelialization epithelialization NOUN bjos-8674720 278 9 of of ADP bjos-8674720 278 10 keratinocyte keratinocyte NOUN bjos-8674720 278 11 scratch scratch NOUN bjos-8674720 278 12 assays assay NOUN bjos-8674720 278 13 by by ADP bjos-8674720 278 14 promoting promote VERB bjos-8674720 278 15 migration migration NOUN bjos-8674720 278 16 . . PUNCT bjos-8674720 279 1 sci sci PROPN bjos-8674720 279 2 rep rep PROPN bjos-8674720 279 3 . . PROPN bjos-8674720 279 4 2015 2015 NUM bjos-8674720 279 5 nov;5:16147 nov;5:16147 NOUN bjos-8674720 279 6 . . PUNCT bjos-8674720 280 1 doi doi NOUN bjos-8674720 280 2 : : PUNCT bjos-8674720 280 3 10.1038 10.1038 NUM bjos-8674720 280 4 / / SYM bjos-8674720 280 5 srep16147 srep16147 PROPN bjos-8674720 280 6 . . PUNCT bjos-8674720 281 1 erratum erratum PROPN bjos-8674720 281 2 in in ADP bjos-8674720 281 3 : : PUNCT bjos-8674720 281 4 sci sci PROPN bjos-8674720 281 5 rep rep PROPN bjos-8674720 281 6 . . PROPN bjos-8674720 281 7 2024 2024 NUM bjos-8674720 281 8 jan jan PROPN bjos-8674720 281 9 25;14(1):2191 25;14(1):2191 NUM bjos-8674720 281 10 . . PUNCT bjos-8674720 281 11 doi doi NOUN bjos-8674720 281 12 : : PUNCT bjos-8674720 281 13 10.1038 10.1038 NUM bjos-8674720 281 14 / / SYM bjos-8674720 281 15 s41598 s41598 NOUN bjos-8674720 281 16 - - PUNCT bjos-8674720 281 17 024 024 NUM bjos-8674720 281 18 - - PUNCT bjos-8674720 281 19 52533 52533 NUM bjos-8674720 281 20 - - SYM bjos-8674720 281 21 2 2 NUM bjos-8674720 281 22 . . NUM bjos-8674720 281 23 21 21 NUM bjos-8674720 281 24 . . PUNCT bjos-8674720 282 1 häkkinen häkkinen PROPN bjos-8674720 282 2 l l PROPN bjos-8674720 282 3 , , PUNCT bjos-8674720 282 4 uitto uitto ADJ bjos-8674720 282 5 vj vj PROPN bjos-8674720 282 6 , , PUNCT bjos-8674720 282 7 larjava larjava PROPN bjos-8674720 282 8 h. h. PROPN bjos-8674720 282 9 cell cell NOUN bjos-8674720 282 10 biology biology NOUN bjos-8674720 282 11 of of ADP bjos-8674720 282 12 gingival gingival NOUN bjos-8674720 282 13 wound wound NOUN bjos-8674720 282 14 healing healing NOUN bjos-8674720 282 15 . . PUNCT bjos-8674720 283 1 periodontol periodontol NOUN bjos-8674720 283 2 2000 2000 NUM bjos-8674720 283 3 . . PUNCT bjos-8674720 284 1 2000 2000 NUM bjos-8674720 284 2 oct;24:127 oct;24:127 PROPN bjos-8674720 284 3 - - SYM bjos-8674720 284 4 52 52 NUM bjos-8674720 284 5 . . PUNCT bjos-8674720 285 1 22 22 NUM bjos-8674720 285 2 . . PUNCT bjos-8674720 286 1 herbert herbert PROPN bjos-8674720 286 2 ba ba PROPN bjos-8674720 286 3 , , PUNCT bjos-8674720 286 4 novince novince NOUN bjos-8674720 286 5 cm cm PROPN bjos-8674720 286 6 , , PUNCT bjos-8674720 286 7 kirkwood kirkwood PROPN bjos-8674720 286 8 kl kl PROPN bjos-8674720 286 9 . . PROPN bjos-8674720 286 10 aggregatibacter aggregatibacter PROPN bjos-8674720 286 11 actinomycetemcomitans actinomycetemcomitan NOUN bjos-8674720 286 12 , , PUNCT bjos-8674720 286 13 a a DET bjos-8674720 286 14 potent potent ADJ bjos-8674720 286 15 immunoregulator immunoregulator NOUN bjos-8674720 286 16 of of ADP bjos-8674720 286 17 the the DET bjos-8674720 286 18 periodontal periodontal ADJ bjos-8674720 286 19 host host NOUN bjos-8674720 286 20 defense defense NOUN bjos-8674720 286 21 system system NOUN bjos-8674720 286 22 and and CCONJ bjos-8674720 286 23 alveolar alveolar ADJ bjos-8674720 286 24 bone bone NOUN bjos-8674720 286 25 homeostasis homeostasis NOUN bjos-8674720 286 26 . . PUNCT bjos-8674720 287 1 mol mol ADP bjos-8674720 287 2 oral oral ADJ bjos-8674720 287 3 microbiol microbiol NOUN bjos-8674720 287 4 . . PUNCT bjos-8674720 288 1 2016 2016 NUM bjos-8674720 288 2 jun;31(3):207 jun;31(3):207 NOUN bjos-8674720 288 3 - - PUNCT bjos-8674720 288 4 27 27 NUM bjos-8674720 288 5 . . PUNCT bjos-8674720 289 1 doi doi NOUN bjos-8674720 289 2 : : PUNCT bjos-8674720 289 3 10.1111 10.1111 NUM bjos-8674720 289 4 / / SYM bjos-8674720 289 5 omi.12119 omi.12119 PROPN bjos-8674720 289 6 . . PUNCT bjos-8674720 290 1 epub epub PROPN bjos-8674720 290 2 2015 2015 NUM bjos-8674720 290 3 sep sep NOUN bjos-8674720 290 4 22 22 NUM bjos-8674720 290 5 . . PUNCT bjos-8674720 291 1 11 11 NUM bjos-8674720 291 2 mendes mende NOUN bjos-8674720 291 3 et et PROPN bjos-8674720 291 4 al al PROPN bjos-8674720 291 5 . . PROPN bjos-8674720 291 6 braz braz PROPN bjos-8674720 291 7 j j PROPN bjos-8674720 291 8 oral oral PROPN bjos-8674720 291 9 sci sci PROPN bjos-8674720 291 10 . . PUNCT bjos-8674720 292 1 2024;23 2024;23 NUM bjos-8674720 292 2 : : PUNCT bjos-8674720 292 3 e244720 e244720 NOUN bjos-8674720 292 4 23 23 NUM bjos-8674720 292 5 . . PUNCT bjos-8674720 293 1 damek damek PROPN bjos-8674720 293 2 - - PUNCT bjos-8674720 293 3 poprawa poprawa PROPN bjos-8674720 293 4 m m PROPN bjos-8674720 293 5 , , PUNCT bjos-8674720 293 6 korostoff korostoff PROPN bjos-8674720 293 7 j j PROPN bjos-8674720 293 8 , , PUNCT bjos-8674720 293 9 gill gill PROPN bjos-8674720 293 10 r r NOUN bjos-8674720 293 11 , , PUNCT bjos-8674720 293 12 dirienzo dirienzo PROPN bjos-8674720 293 13 jm jm PROPN bjos-8674720 293 14 . . PROPN bjos-8674720 293 15 cell cell PROPN bjos-8674720 293 16 junction junction NOUN bjos-8674720 293 17 remodeling remodeling NOUN bjos-8674720 293 18 in in ADP bjos-8674720 293 19 gingival gingival NOUN bjos-8674720 293 20 tissue tissue NOUN bjos-8674720 293 21 exposed expose VERB bjos-8674720 293 22 to to ADP bjos-8674720 293 23 a a DET bjos-8674720 293 24 microbial microbial ADJ bjos-8674720 293 25 toxin toxin NOUN bjos-8674720 293 26 . . PUNCT bjos-8674720 294 1 j j PROPN bjos-8674720 294 2 dent dent NOUN bjos-8674720 294 3 res re NOUN bjos-8674720 294 4 . . PUNCT bjos-8674720 294 5 2013 2013 NUM bjos-8674720 295 1 jun;92(6):518 jun;92(6):518 PROPN bjos-8674720 295 2 - - PUNCT bjos-8674720 295 3 23 23 NUM bjos-8674720 295 4 . . PUNCT bjos-8674720 296 1 doi doi NOUN bjos-8674720 296 2 : : PUNCT bjos-8674720 296 3 10.1177/0022034513486807 10.1177/0022034513486807 NUM bjos-8674720 296 4 . . X bjos-8674720 296 5 24 24 NUM bjos-8674720 296 6 . . X bjos-8674720 296 7 damek damek PROPN bjos-8674720 296 8 - - PUNCT bjos-8674720 296 9 poprawa poprawa PROPN bjos-8674720 296 10 m m PROPN bjos-8674720 296 11 , , PUNCT bjos-8674720 296 12 haris haris PROPN bjos-8674720 296 13 m m PROPN bjos-8674720 296 14 , , PUNCT bjos-8674720 296 15 volgina volgina VERB bjos-8674720 296 16 a a PRON bjos-8674720 296 17 , , PUNCT bjos-8674720 296 18 korostoff korostoff PROPN bjos-8674720 296 19 j j PROPN bjos-8674720 296 20 , , PUNCT bjos-8674720 296 21 dirienzo dirienzo PROPN bjos-8674720 296 22 jm jm PROPN bjos-8674720 296 23 . . PROPN bjos-8674720 296 24 cytolethal cytolethal PROPN bjos-8674720 296 25 distending distend VERB bjos-8674720 296 26 toxin toxin NOUN bjos-8674720 296 27 damages damage NOUN bjos-8674720 296 28 the the DET bjos-8674720 296 29 oral oral ADJ bjos-8674720 296 30 epithelium epithelium NOUN bjos-8674720 296 31 of of ADP bjos-8674720 296 32 gingival gingival NOUN bjos-8674720 296 33 explants explant NOUN bjos-8674720 296 34 . . PUNCT bjos-8674720 297 1 j j PROPN bjos-8674720 297 2 dent dent NOUN bjos-8674720 297 3 res re NOUN bjos-8674720 297 4 . . PUNCT bjos-8674720 298 1 2011 2011 NUM bjos-8674720 298 2 jul;90(7):874 jul;90(7):874 NUM bjos-8674720 298 3 - - PUNCT bjos-8674720 298 4 9 9 NUM bjos-8674720 298 5 . . PUNCT bjos-8674720 298 6 doi doi NOUN bjos-8674720 298 7 : : PUNCT bjos-8674720 298 8 10.1177/0022034511403743 10.1177/0022034511403743 NUM bjos-8674720 298 9 . . NOUN bjos-8674720 298 10 25 25 NUM bjos-8674720 298 11 . . PUNCT bjos-8674720 299 1 duarte duarte PROPN bjos-8674720 299 2 pm pm PROPN bjos-8674720 299 3 , , PUNCT bjos-8674720 299 4 bastos bastos PROPN bjos-8674720 299 5 mf mf VERB bjos-8674720 299 6 , , PUNCT bjos-8674720 299 7 fermiano fermiano ADJ bjos-8674720 299 8 d d NOUN bjos-8674720 299 9 , , PUNCT bjos-8674720 299 10 rabelo rabelo NOUN bjos-8674720 299 11 cc cc PROPN bjos-8674720 299 12 , , PUNCT bjos-8674720 299 13 perez perez PROPN bjos-8674720 299 14 - - PUNCT bjos-8674720 299 15 chaparro chaparro PROPN bjos-8674720 299 16 pj pj PROPN bjos-8674720 299 17 , , PUNCT bjos-8674720 299 18 figueiredo figueiredo PROPN bjos-8674720 299 19 lc lc PROPN bjos-8674720 299 20 , , PUNCT bjos-8674720 300 1 et et PROPN bjos-8674720 300 2     SPACE bjos-8674720 300 3 al al PROPN bjos-8674720 300 4 . . PROPN bjos-8674720 300 5 do do VERB bjos-8674720 300 6 subjects subject NOUN bjos-8674720 300 7 with with ADP bjos-8674720 300 8 aggressive aggressive ADJ bjos-8674720 300 9 and and CCONJ bjos-8674720 300 10 chronic chronic ADJ bjos-8674720 300 11 periodontitis periodontitis NOUN bjos-8674720 300 12 exhibit exhibit VERB bjos-8674720 300 13 a a DET bjos-8674720 300 14 different different ADJ bjos-8674720 300 15 cytokine cytokine NOUN bjos-8674720 300 16 / / SYM bjos-8674720 300 17 chemokine chemokine ADJ bjos-8674720 300 18 profile profile NOUN bjos-8674720 300 19 in in ADP bjos-8674720 300 20 the the DET bjos-8674720 300 21 gingival gingival NOUN bjos-8674720 300 22 crevicular crevicular ADJ bjos-8674720 300 23 fluid fluid NOUN bjos-8674720 300 24 ? ? PUNCT bjos-8674720 301 1 a a DET bjos-8674720 301 2 systematic systematic ADJ bjos-8674720 301 3 review review NOUN bjos-8674720 301 4 . . PUNCT bjos-8674720 302 1 j j PROPN bjos-8674720 302 2 periodontal periodontal ADJ bjos-8674720 302 3 res re NOUN bjos-8674720 302 4 . . PROPN bjos-8674720 302 5 2015 2015 NUM bjos-8674720 302 6 feb;50(1):18 feb;50(1):18 PROPN bjos-8674720 302 7 - - PUNCT bjos-8674720 302 8 27 27 NUM bjos-8674720 302 9 . . PUNCT bjos-8674720 303 1 doi doi NOUN bjos-8674720 303 2 : : PUNCT bjos-8674720 303 3 10.1111 10.1111 NUM bjos-8674720 303 4 / / SYM bjos-8674720 303 5 jre.12180 jre.12180 PROPN bjos-8674720 303 6 . . PUNCT bjos-8674720 304 1 epub epub PROPN bjos-8674720 304 2 2014 2014 NUM bjos-8674720 304 3     SPACE bjos-8674720 304 4 mar mar PROPN bjos-8674720 304 5 25 25 NUM bjos-8674720 304 6 . . PUNCT