id	sid	tid	token	lemma	pos
bjos-8676163	1	1	1	1	NUM
bjos-8676163	1	2	volume	volume	NOUN
bjos-8676163	1	3	23	23	NUM
bjos-8676163	1	4	2024	2024	NUM
bjos-8676163	1	5	e246163	e246163	NUM
bjos-8676163	1	6	original	original	ADJ
bjos-8676163	1	7	research	research	NOUN
bjos-8676163	1	8	braz	braz	PROPN
bjos-8676163	1	9	j	j	PROPN
bjos-8676163	1	10	oral	oral	PROPN
bjos-8676163	1	11	sci	sci	PROPN
bjos-8676163	1	12	.	.	PUNCT
bjos-8676163	2	1	2024;23	2024;23	NUM
bjos-8676163	2	2	:	:	PUNCT
bjos-8676163	2	3	e246163http://dx.doi.org/10.20396	e246163http://dx.doi.org/10.20396	SYM
bjos-8676163	2	4	/	/	SYM
bjos-8676163	2	5	bjos.v23i00.8676163	bjos.v23i00.8676163	NOUN
bjos-8676163	2	6	1	1	NUM
bjos-8676163	2	7	faculdade	faculdade	NOUN
bjos-8676163	2	8	de	de	X
bjos-8676163	2	9	odontologia	odontologia	X
bjos-8676163	2	10	de	de	X
bjos-8676163	2	11	piracicaba	piracicaba	PROPN
bjos-8676163	2	12	(	(	PUNCT
bjos-8676163	2	13	fop	fop	ADJ
bjos-8676163	2	14	)	)	PUNCT
bjos-8676163	2	15	,	,	PUNCT
bjos-8676163	2	16	universidade	universidade	PROPN
bjos-8676163	2	17	estadual	estadual	PROPN
bjos-8676163	2	18	de	de	PROPN
bjos-8676163	2	19	campinas	campinas	PROPN
bjos-8676163	2	20	(	(	PUNCT
bjos-8676163	2	21	unicamp	unicamp	PROPN
bjos-8676163	2	22	)	)	PUNCT
bjos-8676163	2	23	,	,	PUNCT
bjos-8676163	2	24	piracicaba	piracicaba	PROPN
bjos-8676163	2	25	,	,	PUNCT
bjos-8676163	2	26	sp	sp	NOUN
bjos-8676163	2	27	,	,	PUNCT
bjos-8676163	2	28	brazil	brazil	PROPN
bjos-8676163	2	29	.	.	PUNCT
bjos-8676163	3	1	2	2	NUM
bjos-8676163	3	2	institute	institute	NOUN
bjos-8676163	3	3	of	of	ADP
bjos-8676163	3	4	oral	oral	ADJ
bjos-8676163	3	5	biology	biology	NOUN
bjos-8676163	3	6	,	,	PUNCT
bjos-8676163	3	7	faculty	faculty	NOUN
bjos-8676163	3	8	of	of	ADP
bjos-8676163	3	9	dentistry	dentistry	NOUN
bjos-8676163	3	10	,	,	PUNCT
bjos-8676163	3	11	university	university	PROPN
bjos-8676163	3	12	of	of	ADP
bjos-8676163	3	13	oslo	oslo	PROPN
bjos-8676163	3	14	,	,	PUNCT
bjos-8676163	3	15	oslo	oslo	PROPN
bjos-8676163	3	16	,	,	PUNCT
bjos-8676163	3	17	norway	norway	PROPN
bjos-8676163	3	18	.	.	PUNCT
bjos-8676163	4	1	3	3	NUM
bjos-8676163	4	2	são	são	PROPN
bjos-8676163	4	3	carlos	carlos	PROPN
bjos-8676163	4	4	institute	institute	PROPN
bjos-8676163	4	5	of	of	ADP
bjos-8676163	4	6	physics	physics	PROPN
bjos-8676163	4	7	,	,	PUNCT
bjos-8676163	4	8	university	university	PROPN
bjos-8676163	4	9	of	of	ADP
bjos-8676163	4	10	são	são	PROPN
bjos-8676163	4	11	paulo	paulo	PROPN
bjos-8676163	4	12	,	,	PUNCT
bjos-8676163	4	13	são	são	PROPN
bjos-8676163	4	14	carlos	carlos	PROPN
bjos-8676163	4	15	,	,	PUNCT
bjos-8676163	4	16	sp	sp	PROPN
bjos-8676163	4	17	,	,	PUNCT
bjos-8676163	4	18	brazil	brazil	PROPN
bjos-8676163	4	19	.	.	PUNCT
bjos-8676163	5	1	corresponding	correspond	VERB
bjos-8676163	5	2	author	author	NOUN
bjos-8676163	5	3	:	:	PUNCT
bjos-8676163	5	4	antonio	antonio	PROPN
bjos-8676163	5	5	pedro	pedro	PROPN
bjos-8676163	5	6	ricomini	ricomini	PROPN
bjos-8676163	5	7	filho	filho	PROPN
bjos-8676163	5	8	department	department	PROPN
bjos-8676163	5	9	of	of	ADP
bjos-8676163	5	10	biosciences	bioscience	NOUN
bjos-8676163	5	11	,	,	PUNCT
bjos-8676163	5	12	faculdade	faculdade	PROPN
bjos-8676163	5	13	de	de	X
bjos-8676163	5	14	odontologia	odontologia	X
bjos-8676163	5	15	de	de	X
bjos-8676163	5	16	piracicaba	piracicaba	PROPN
bjos-8676163	5	17	(	(	PUNCT
bjos-8676163	5	18	fop	fop	ADJ
bjos-8676163	5	19	)	)	PUNCT
bjos-8676163	5	20	,	,	PUNCT
bjos-8676163	5	21	universidade	universidade	PROPN
bjos-8676163	5	22	estadual	estadual	PROPN
bjos-8676163	5	23	de	de	PROPN
bjos-8676163	5	24	campinas	campinas	PROPN
bjos-8676163	5	25	(	(	PUNCT
bjos-8676163	5	26	unicamp	unicamp	PROPN
bjos-8676163	5	27	)	)	PUNCT
bjos-8676163	5	28	avenida	avenida	PROPN
bjos-8676163	5	29	limeira	limeira	PROPN
bjos-8676163	5	30	,	,	PUNCT
bjos-8676163	5	31	nº	nº	ADV
bjos-8676163	5	32	901	901	NUM
bjos-8676163	5	33	,	,	PUNCT
bjos-8676163	5	34	areião	areião	NOUN
bjos-8676163	5	35	,	,	PUNCT
bjos-8676163	5	36	cep	cep	NOUN
bjos-8676163	5	37	13414	13414	NUM
bjos-8676163	5	38	-	-	SYM
bjos-8676163	5	39	903	903	NUM
bjos-8676163	5	40	,	,	PUNCT
bjos-8676163	5	41	piracicaba	piracicaba	PROPN
bjos-8676163	5	42	,	,	PUNCT
bjos-8676163	5	43	sp	sp	NOUN
bjos-8676163	5	44	,	,	PUNCT
bjos-8676163	5	45	brazil	brazil	PROPN
bjos-8676163	5	46	.	.	PUNCT
bjos-8676163	6	1	e	e	X
bjos-8676163	6	2	-	-	NOUN
bjos-8676163	6	3	mail	mail	NOUN
bjos-8676163	6	4	:	:	PUNCT
bjos-8676163	6	5	ricomini@unicamp.br	ricomini@unicamp.br	PROPN
bjos-8676163	6	6	editor	editor	NOUN
bjos-8676163	6	7	:	:	PUNCT
bjos-8676163	6	8	dr	dr	PROPN
bjos-8676163	6	9	.	.	PROPN
bjos-8676163	6	10	altair	altair	PROPN
bjos-8676163	6	11	a.	a.	PROPN
bjos-8676163	6	12	del	del	PROPN
bjos-8676163	6	13	bel	bel	PROPN
bjos-8676163	6	14	cury	cury	PROPN
bjos-8676163	6	15	received	receive	VERB
bjos-8676163	6	16	:	:	PUNCT
bjos-8676163	6	17	april	april	PROPN
bjos-8676163	6	18	02	02	NUM
bjos-8676163	6	19	,	,	PUNCT
bjos-8676163	6	20	2024	2024	NUM
bjos-8676163	6	21	accepted	accept	VERB
bjos-8676163	6	22	:	:	PUNCT
bjos-8676163	6	23	june	june	PROPN
bjos-8676163	6	24	04	04	NUM
bjos-8676163	6	25	,	,	PUNCT
bjos-8676163	6	26	2024	2024	NUM
bjos-8676163	6	27	absence	absence	NOUN
bjos-8676163	6	28	of	of	ADP
bjos-8676163	6	29	inhibitory	inhibitory	ADJ
bjos-8676163	6	30	effects	effect	NOUN
bjos-8676163	6	31	of	of	ADP
bjos-8676163	6	32	two	two	NUM
bjos-8676163	6	33	new	new	ADJ
bjos-8676163	6	34	glucanases	glucanase	NOUN
bjos-8676163	6	35	on	on	ADP
bjos-8676163	6	36	streptococcus	streptococcus	NOUN
bjos-8676163	6	37	mutans	mutan	NOUN
bjos-8676163	6	38	growth	growth	NOUN
bjos-8676163	6	39	mateus	mateus	PROPN
bjos-8676163	6	40	xavier	xavier	PROPN
bjos-8676163	6	41	-	-	PUNCT
bjos-8676163	6	42	queiroz1,2	queiroz1,2	PROPN
bjos-8676163	6	43	,	,	PUNCT
bjos-8676163	6	44	pedro	pedro	PROPN
bjos-8676163	6	45	ricardo	ricardo	PROPN
bjos-8676163	6	46	vieira	vieira	PROPN
bjos-8676163	6	47	hamann3	hamann3	PROPN
bjos-8676163	6	48	,	,	PUNCT
bjos-8676163	6	49	heidi	heidi	PROPN
bjos-8676163	6	50	aarø	aarø	PROPN
bjos-8676163	6	51	åmdal2	åmdal2	PROPN
bjos-8676163	6	52	,	,	PUNCT
bjos-8676163	6	53	igor	igor	PROPN
bjos-8676163	6	54	polikarpov3	polikarpov3	PROPN
bjos-8676163	6	55	,	,	PUNCT
bjos-8676163	6	56	fernanda	fernanda	PROPN
bjos-8676163	6	57	cristina	cristina	PROPN
bjos-8676163	6	58	petersen2	petersen2	PROPN
bjos-8676163	6	59	,	,	PUNCT
bjos-8676163	6	60	antônio	antônio	PROPN
bjos-8676163	6	61	pedro	pedro	PROPN
bjos-8676163	6	62	ricomini	ricomini	PROPN
bjos-8676163	6	63	-	-	PUNCT
bjos-8676163	6	64	filho1	filho1	ADJ
bjos-8676163	6	65	*	*	PUNCT
bjos-8676163	6	66	glucanohydrolases	glucanohydrolase	NOUN
bjos-8676163	6	67	have	have	AUX
bjos-8676163	6	68	shown	show	VERB
bjos-8676163	6	69	promise	promise	NOUN
bjos-8676163	6	70	in	in	ADP
bjos-8676163	6	71	degrading	degrade	VERB
bjos-8676163	6	72	exopolysaccharides	exopolysaccharide	NOUN
bjos-8676163	6	73	in	in	ADP
bjos-8676163	6	74	cariogenic	cariogenic	ADJ
bjos-8676163	6	75	biofilms	biofilm	NOUN
bjos-8676163	6	76	,	,	PUNCT
bjos-8676163	6	77	making	make	VERB
bjos-8676163	6	78	them	they	PRON
bjos-8676163	6	79	a	a	DET
bjos-8676163	6	80	potential	potential	ADJ
bjos-8676163	6	81	strategy	strategy	NOUN
bjos-8676163	6	82	for	for	ADP
bjos-8676163	6	83	biofilm	biofilm	NOUN
bjos-8676163	6	84	control	control	NOUN
bjos-8676163	6	85	without	without	ADP
bjos-8676163	6	86	disrupting	disrupt	VERB
bjos-8676163	6	87	the	the	DET
bjos-8676163	6	88	oral	oral	ADJ
bjos-8676163	6	89	microbiota	microbiota	NOUN
bjos-8676163	6	90	.	.	PUNCT
bjos-8676163	7	1	however	however	ADV
bjos-8676163	7	2	,	,	PUNCT
bjos-8676163	7	3	their	their	PRON
bjos-8676163	7	4	direct	direct	ADJ
bjos-8676163	7	5	antimicrobial	antimicrobial	ADJ
bjos-8676163	7	6	effects	effect	NOUN
bjos-8676163	7	7	remain	remain	VERB
bjos-8676163	7	8	unclear	unclear	ADJ
bjos-8676163	7	9	.	.	PUNCT
bjos-8676163	8	1	aim	aim	VERB
bjos-8676163	8	2	:	:	PUNCT
bjos-8676163	8	3	to	to	PART
bjos-8676163	8	4	determine	determine	VERB
bjos-8676163	8	5	the	the	DET
bjos-8676163	8	6	antimicrobial	antimicrobial	ADJ
bjos-8676163	8	7	activity	activity	NOUN
bjos-8676163	8	8	on	on	ADP
bjos-8676163	8	9	s.	s.	PROPN
bjos-8676163	8	10	mutans	mutans	PROPN
bjos-8676163	8	11	of	of	ADP
bjos-8676163	8	12	two	two	NUM
bjos-8676163	8	13	newly	newly	ADV
bjos-8676163	8	14	discovered	discover	VERB
bjos-8676163	8	15	glucanases	glucanase	NOUN
bjos-8676163	8	16	characterized	characterize	VERB
bjos-8676163	8	17	by	by	ADP
bjos-8676163	8	18	our	our	PRON
bjos-8676163	8	19	group	group	NOUN
bjos-8676163	8	20	,	,	PUNCT
bjos-8676163	8	21	pmgh87	pmgh87	NOUN
bjos-8676163	8	22	(	(	PUNCT
bjos-8676163	8	23	mutanase	mutanase	PROPN
bjos-8676163	8	24	)	)	PUNCT
bjos-8676163	8	25	from	from	ADP
bjos-8676163	8	26	prevotella	prevotella	NOUN
bjos-8676163	8	27	melaninogenica	melaninogenica	NOUN
bjos-8676163	8	28	and	and	CCONJ
bjos-8676163	8	29	cogh66	cogh66	NOUN
bjos-8676163	8	30	(	(	PUNCT
bjos-8676163	8	31	dextranase	dextranase	NOUN
bjos-8676163	8	32	)	)	PUNCT
bjos-8676163	8	33	from	from	ADP
bjos-8676163	8	34	capnocytophaga	capnocytophaga	PROPN
bjos-8676163	8	35	ochracea	ochracea	PROPN
bjos-8676163	8	36	,	,	PUNCT
bjos-8676163	8	37	using	use	VERB
bjos-8676163	8	38	a	a	DET
bjos-8676163	8	39	commercial	commercial	ADJ
bjos-8676163	8	40	dextranase	dextranase	NOUN
bjos-8676163	8	41	from	from	ADP
bjos-8676163	8	42	penicillum	penicillum	NOUN
bjos-8676163	8	43	sp	sp	NOUN
bjos-8676163	8	44	.	.	PROPN
bjos-8676163	8	45	as	as	ADP
bjos-8676163	8	46	a	a	DET
bjos-8676163	8	47	control	control	NOUN
bjos-8676163	8	48	.	.	PUNCT
bjos-8676163	9	1	methods	method	NOUN
bjos-8676163	9	2	:	:	PUNCT
bjos-8676163	9	3	their	their	PRON
bjos-8676163	9	4	effects	effect	NOUN
bjos-8676163	9	5	on	on	ADP
bjos-8676163	9	6	growth	growth	NOUN
bjos-8676163	9	7	were	be	AUX
bjos-8676163	9	8	assessed	assess	VERB
bjos-8676163	9	9	using	use	VERB
bjos-8676163	9	10	a	a	DET
bjos-8676163	9	11	luciferase	luciferase	ADJ
bjos-8676163	9	12	reporter	reporter	NOUN
bjos-8676163	9	13	system	system	NOUN
bjos-8676163	9	14	coupled	couple	VERB
bjos-8676163	9	15	with	with	ADP
bjos-8676163	9	16	the	the	DET
bjos-8676163	9	17	promoter	promoter	NOUN
bjos-8676163	9	18	of	of	ADP
bjos-8676163	9	19	the	the	DET
bjos-8676163	9	20	ldh	ldh	PROPN
bjos-8676163	9	21	gene	gene	NOUN
bjos-8676163	9	22	in	in	ADP
bjos-8676163	9	23	streptococcus	streptococcus	NOUN
bjos-8676163	9	24	mutans	mutan	NOUN
bjos-8676163	9	25	.	.	PUNCT
bjos-8676163	10	1	results	result	NOUN
bjos-8676163	10	2	:	:	PUNCT
bjos-8676163	10	3	quantification	quantification	NOUN
bjos-8676163	10	4	of	of	ADP
bjos-8676163	10	5	optical	optical	ADJ
bjos-8676163	10	6	density	density	NOUN
bjos-8676163	10	7	and	and	CCONJ
bjos-8676163	10	8	luminescence	luminescence	NOUN
bjos-8676163	10	9	over	over	ADP
bjos-8676163	10	10	a	a	DET
bjos-8676163	10	11	10	10	NUM
bjos-8676163	10	12	-	-	PUNCT
bjos-8676163	10	13	hour	hour	NOUN
bjos-8676163	10	14	growth	growth	NOUN
bjos-8676163	10	15	period	period	NOUN
bjos-8676163	10	16	revealed	reveal	VERB
bjos-8676163	10	17	that	that	SCONJ
bjos-8676163	10	18	the	the	DET
bjos-8676163	10	19	commercial	commercial	ADJ
bjos-8676163	10	20	dextranase	dextranase	NOUN
bjos-8676163	10	21	exhibited	exhibit	VERB
bjos-8676163	10	22	inhibitory	inhibitory	ADJ
bjos-8676163	10	23	effects	effect	NOUN
bjos-8676163	10	24	on	on	ADP
bjos-8676163	10	25	s.	s.	PROPN
bjos-8676163	10	26	mutans	mutans	PROPN
bjos-8676163	10	27	growth	growth	NOUN
bjos-8676163	10	28	.	.	PUNCT
bjos-8676163	11	1	however	however	ADV
bjos-8676163	11	2	,	,	PUNCT
bjos-8676163	11	3	these	these	DET
bjos-8676163	11	4	effects	effect	NOUN
bjos-8676163	11	5	were	be	AUX
bjos-8676163	11	6	neutralized	neutralize	VERB
bjos-8676163	11	7	by	by	ADP
bjos-8676163	11	8	heat	heat	NOUN
bjos-8676163	11	9	treatment	treatment	NOUN
bjos-8676163	11	10	,	,	PUNCT
bjos-8676163	11	11	suggesting	suggest	VERB
bjos-8676163	11	12	the	the	DET
bjos-8676163	11	13	presence	presence	NOUN
bjos-8676163	11	14	of	of	ADP
bjos-8676163	11	15	a	a	DET
bjos-8676163	11	16	heat	heat	NOUN
bjos-8676163	11	17	-	-	PUNCT
bjos-8676163	11	18	sensitive	sensitive	ADJ
bjos-8676163	11	19	contaminant	contaminant	NOUN
bjos-8676163	11	20	or	or	CCONJ
bjos-8676163	11	21	an	an	DET
bjos-8676163	11	22	additional	additional	ADJ
bjos-8676163	11	23	antimicrobial	antimicrobial	ADJ
bjos-8676163	11	24	property	property	NOUN
bjos-8676163	11	25	associated	associate	VERB
bjos-8676163	11	26	with	with	ADP
bjos-8676163	11	27	the	the	DET
bjos-8676163	11	28	commercial	commercial	ADJ
bjos-8676163	11	29	dextranase	dextranase	NOUN
bjos-8676163	11	30	from	from	ADP
bjos-8676163	11	31	penicillum	penicillum	NOUN
bjos-8676163	11	32	sp	sp	NOUN
bjos-8676163	11	33	.	.	PROPN
bjos-8676163	12	1	on	on	ADP
bjos-8676163	12	2	the	the	DET
bjos-8676163	12	3	other	other	ADJ
bjos-8676163	12	4	hand	hand	NOUN
bjos-8676163	12	5	,	,	PUNCT
bjos-8676163	12	6	the	the	DET
bjos-8676163	12	7	purified	purified	ADJ
bjos-8676163	12	8	mutanase	mutanase	NOUN
bjos-8676163	12	9	and	and	CCONJ
bjos-8676163	12	10	dextranase	dextranase	NOUN
bjos-8676163	12	11	enzymes	enzyme	NOUN
bjos-8676163	12	12	had	have	VERB
bjos-8676163	12	13	no	no	DET
bjos-8676163	12	14	inhibitory	inhibitory	ADJ
bjos-8676163	12	15	effect	effect	NOUN
bjos-8676163	12	16	on	on	ADP
bjos-8676163	12	17	s.	s.	PROPN
bjos-8676163	12	18	mutans	mutans	PROPN
bjos-8676163	12	19	growth	growth	NOUN
bjos-8676163	12	20	.	.	PUNCT
bjos-8676163	13	1	conclusion	conclusion	NOUN
bjos-8676163	13	2	:	:	PUNCT
bjos-8676163	13	3	in	in	ADP
bjos-8676163	13	4	conclusion	conclusion	NOUN
bjos-8676163	13	5	,	,	PUNCT
bjos-8676163	13	6	the	the	DET
bjos-8676163	13	7	absence	absence	NOUN
bjos-8676163	13	8	of	of	ADP
bjos-8676163	13	9	inhibitory	inhibitory	ADJ
bjos-8676163	13	10	effects	effect	NOUN
bjos-8676163	13	11	on	on	ADP
bjos-8676163	13	12	s.	s.	PROPN
bjos-8676163	13	13	mutans	mutans	PROPN
bjos-8676163	13	14	growth	growth	NOUN
bjos-8676163	13	15	by	by	ADP
bjos-8676163	13	16	the	the	DET
bjos-8676163	13	17	newly	newly	ADV
bjos-8676163	13	18	discovered	discover	VERB
bjos-8676163	13	19	enzymes	enzyme	NOUN
bjos-8676163	13	20	emphasizes	emphasize	VERB
bjos-8676163	13	21	their	their	PRON
bjos-8676163	13	22	potential	potential	NOUN
bjos-8676163	13	23	for	for	ADP
bjos-8676163	13	24	biofilm	biofilm	NOUN
bjos-8676163	13	25	control	control	NOUN
bjos-8676163	13	26	while	while	SCONJ
bjos-8676163	13	27	preserving	preserve	VERB
bjos-8676163	13	28	the	the	DET
bjos-8676163	13	29	delicate	delicate	ADJ
bjos-8676163	13	30	balance	balance	NOUN
bjos-8676163	13	31	of	of	ADP
bjos-8676163	13	32	the	the	DET
bjos-8676163	13	33	oral	oral	ADJ
bjos-8676163	13	34	microbiota	microbiota	NOUN
bjos-8676163	13	35	and	and	CCONJ
bjos-8676163	13	36	preventing	prevent	VERB
bjos-8676163	13	37	the	the	DET
bjos-8676163	13	38	emergence	emergence	NOUN
bjos-8676163	13	39	of	of	ADP
bjos-8676163	13	40	resistance	resistance	NOUN
bjos-8676163	13	41	.	.	PUNCT
bjos-8676163	14	1	keywords	keyword	NOUN
bjos-8676163	14	2	:	:	PUNCT
bjos-8676163	14	3	streptococcus	streptococcus	NOUN
bjos-8676163	14	4	mutans	mutan	NOUN
bjos-8676163	14	5	.	.	PUNCT
bjos-8676163	15	1	dextranase	dextranase	NOUN
bjos-8676163	15	2	.	.	PUNCT
bjos-8676163	16	1	anti	anti	ADJ
bjos-8676163	16	2	-	-	ADJ
bjos-8676163	16	3	infective	infective	ADJ
bjos-8676163	16	4	agent	agent	NOUN
bjos-8676163	16	5	.	.	PUNCT
bjos-8676163	17	1	https://orcid.org/0000-0001-8292-1230	https://orcid.org/0000-0001-8292-1230	VERB
bjos-8676163	17	2	https://orcid.org/0000-0002-6654-0646	https://orcid.org/0000-0002-6654-0646	VERB
bjos-8676163	17	3	https://orcid.org/0000-0001-9496-4174	https://orcid.org/0000-0001-9496-4174	PROPN
bjos-8676163	17	4	https://orcid.org/0000-0003-4649-247x	https://orcid.org/0000-0003-4649-247x	PROPN
bjos-8676163	17	5	https://orcid.org/0000-0002-6593-6040	https://orcid.org/0000-0002-6593-6040	NOUN
bjos-8676163	17	6	2	2	NUM
bjos-8676163	17	7	queiroz	queiroz	ADV
bjos-8676163	17	8	et	et	PROPN
bjos-8676163	18	1	al	al	PROPN
bjos-8676163	18	2	.	.	PROPN
bjos-8676163	18	3	braz	braz	PROPN
bjos-8676163	18	4	j	j	PROPN
bjos-8676163	18	5	oral	oral	PROPN
bjos-8676163	18	6	sci	sci	PROPN
bjos-8676163	18	7	.	.	PUNCT
bjos-8676163	19	1	2024;23	2024;23	NUM
bjos-8676163	19	2	:	:	PUNCT
bjos-8676163	19	3	e246163	e246163	NOUN
bjos-8676163	19	4	introduction	introduction	NOUN
bjos-8676163	19	5	glucanohydrolases	glucanohydrolase	NOUN
bjos-8676163	19	6	have	have	AUX
bjos-8676163	19	7	demonstrated	demonstrate	VERB
bjos-8676163	19	8	potential	potential	NOUN
bjos-8676163	19	9	in	in	ADP
bjos-8676163	19	10	degrading	degrade	VERB
bjos-8676163	19	11	biofilms	biofilm	NOUN
bjos-8676163	19	12	by	by	ADP
bjos-8676163	19	13	specifically	specifically	ADV
bjos-8676163	19	14	targeting	target	VERB
bjos-8676163	19	15	the	the	DET
bjos-8676163	19	16	polysaccharides	polysaccharide	NOUN
bjos-8676163	19	17	within	within	ADP
bjos-8676163	19	18	the	the	DET
bjos-8676163	19	19	extracellular	extracellular	ADJ
bjos-8676163	19	20	matrix1	matrix1	NOUN
bjos-8676163	19	21	.	.	PUNCT
bjos-8676163	20	1	in	in	ADP
bjos-8676163	20	2	the	the	DET
bjos-8676163	20	3	oral	oral	ADJ
bjos-8676163	20	4	cavity	cavity	NOUN
bjos-8676163	20	5	,	,	PUNCT
bjos-8676163	20	6	biofilms	biofilm	NOUN
bjos-8676163	20	7	are	be	AUX
bjos-8676163	20	8	constantly	constantly	ADV
bjos-8676163	20	9	formed	form	VERB
bjos-8676163	20	10	on	on	ADP
bjos-8676163	20	11	tooth	tooth	NOUN
bjos-8676163	20	12	surfaces	surface	NOUN
bjos-8676163	20	13	,	,	PUNCT
bjos-8676163	20	14	and	and	CCONJ
bjos-8676163	20	15	due	due	ADP
bjos-8676163	20	16	to	to	ADP
bjos-8676163	20	17	the	the	DET
bjos-8676163	20	18	frequent	frequent	ADJ
bjos-8676163	20	19	consumption	consumption	NOUN
bjos-8676163	20	20	of	of	ADP
bjos-8676163	20	21	sucrose	sucrose	PROPN
bjos-8676163	20	22	,	,	PUNCT
bjos-8676163	20	23	large	large	ADJ
bjos-8676163	20	24	amounts	amount	NOUN
bjos-8676163	20	25	of	of	ADP
bjos-8676163	20	26	extracellular	extracellular	ADJ
bjos-8676163	20	27	polysaccharides	polysaccharide	NOUN
bjos-8676163	20	28	(	(	PUNCT
bjos-8676163	20	29	eps	eps	NOUN
bjos-8676163	20	30	)	)	PUNCT
bjos-8676163	20	31	are	be	AUX
bjos-8676163	20	32	synthesized	synthesize	VERB
bjos-8676163	20	33	,	,	PUNCT
bjos-8676163	20	34	mainly	mainly	ADV
bjos-8676163	20	35	glucans	glucan	NOUN
bjos-8676163	20	36	,	,	PUNCT
bjos-8676163	20	37	such	such	ADJ
bjos-8676163	20	38	as	as	ADP
bjos-8676163	20	39	α(1→3)-linked	α(1→3)-linke	VERB
bjos-8676163	20	40	(	(	PUNCT
bjos-8676163	20	41	mutans	mutan	NOUN
bjos-8676163	20	42	)	)	PUNCT
bjos-8676163	20	43	and	and	CCONJ
bjos-8676163	20	44	α(1→6)-linked	α(1→6)-linked	NUM
bjos-8676163	20	45	(	(	PUNCT
bjos-8676163	20	46	dextrans	dextran	NOUN
bjos-8676163	20	47	)	)	PUNCT
bjos-8676163	21	1	glucans2	glucans2	PROPN
bjos-8676163	21	2	.	.	PUNCT
bjos-8676163	22	1	eps	eps	PROPN
bjos-8676163	22	2	favor	favor	VERB
bjos-8676163	22	3	the	the	DET
bjos-8676163	22	4	adhesion	adhesion	NOUN
bjos-8676163	22	5	and	and	CCONJ
bjos-8676163	22	6	accumulation	accumulation	NOUN
bjos-8676163	22	7	of	of	ADP
bjos-8676163	22	8	biofilm	biofilm	NOUN
bjos-8676163	22	9	,	,	PUNCT
bjos-8676163	22	10	and	and	CCONJ
bjos-8676163	22	11	if	if	SCONJ
bjos-8676163	22	12	not	not	PART
bjos-8676163	22	13	removed	remove	VERB
bjos-8676163	22	14	,	,	PUNCT
bjos-8676163	22	15	contribute	contribute	VERB
bjos-8676163	22	16	to	to	ADP
bjos-8676163	22	17	the	the	DET
bjos-8676163	22	18	development	development	NOUN
bjos-8676163	22	19	of	of	ADP
bjos-8676163	22	20	dental	dental	ADJ
bjos-8676163	22	21	caries	carie	NOUN
bjos-8676163	22	22	.	.	PUNCT
bjos-8676163	23	1	therefore	therefore	ADV
bjos-8676163	23	2	,	,	PUNCT
bjos-8676163	23	3	the	the	DET
bjos-8676163	23	4	degradation	degradation	NOUN
bjos-8676163	23	5	of	of	ADP
bjos-8676163	23	6	dextrans	dextran	NOUN
bjos-8676163	23	7	and	and	CCONJ
bjos-8676163	23	8	mutans	mutan	NOUN
bjos-8676163	23	9	by	by	ADP
bjos-8676163	23	10	the	the	DET
bjos-8676163	23	11	enzymes	enzyme	NOUN
bjos-8676163	23	12	α(1→3)and	α(1→3)and	NUM
bjos-8676163	23	13	α(1→6)-glucanases	α(1→6)-glucanase	NOUN
bjos-8676163	23	14	(	(	PUNCT
bjos-8676163	23	15	mutanase	mutanase	NOUN
bjos-8676163	23	16	and	and	CCONJ
bjos-8676163	23	17	dextranase	dextranase	NOUN
bjos-8676163	23	18	,	,	PUNCT
bjos-8676163	23	19	respectively	respectively	ADV
bjos-8676163	23	20	)	)	PUNCT
bjos-8676163	23	21	have	have	AUX
bjos-8676163	23	22	shown	show	VERB
bjos-8676163	23	23	promise	promise	NOUN
bjos-8676163	23	24	in	in	ADP
bjos-8676163	23	25	degrading	degrade	VERB
bjos-8676163	23	26	exopolysaccharides	exopolysaccharide	NOUN
bjos-8676163	23	27	in	in	ADP
bjos-8676163	23	28	oral	oral	ADJ
bjos-8676163	23	29	biofilms3	biofilms3	NOUN
bjos-8676163	23	30	.	.	PUNCT
bjos-8676163	24	1	furthermore	furthermore	ADV
bjos-8676163	24	2	,	,	PUNCT
bjos-8676163	24	3	these	these	DET
bjos-8676163	24	4	enzymes	enzyme	NOUN
bjos-8676163	24	5	exhibit	exhibit	VERB
bjos-8676163	24	6	substrate	substrate	NOUN
bjos-8676163	24	7	-	-	PUNCT
bjos-8676163	24	8	specificity	specificity	NOUN
bjos-8676163	24	9	,	,	PUNCT
bjos-8676163	24	10	making	make	VERB
bjos-8676163	24	11	them	they	PRON
bjos-8676163	24	12	a	a	DET
bjos-8676163	24	13	potential	potential	ADJ
bjos-8676163	24	14	strategy	strategy	NOUN
bjos-8676163	24	15	for	for	ADP
bjos-8676163	24	16	controlling	control	VERB
bjos-8676163	24	17	biofilms	biofilm	NOUN
bjos-8676163	24	18	without	without	ADP
bjos-8676163	24	19	disrupting	disrupt	VERB
bjos-8676163	24	20	the	the	DET
bjos-8676163	24	21	oral	oral	ADJ
bjos-8676163	24	22	microbiota4	microbiota4	NOUN
bjos-8676163	24	23	.	.	PUNCT
bjos-8676163	25	1	this	this	PRON
bjos-8676163	25	2	differentiates	differentiate	VERB
bjos-8676163	25	3	them	they	PRON
bjos-8676163	25	4	from	from	ADP
bjos-8676163	25	5	traditional	traditional	ADJ
bjos-8676163	25	6	antimicrobial	antimicrobial	ADJ
bjos-8676163	25	7	therapies	therapy	NOUN
bjos-8676163	25	8	,	,	PUNCT
bjos-8676163	25	9	which	which	PRON
bjos-8676163	25	10	may	may	AUX
bjos-8676163	25	11	harm	harm	VERB
bjos-8676163	25	12	the	the	DET
bjos-8676163	25	13	commensal	commensal	ADJ
bjos-8676163	25	14	microbiota	microbiota	NOUN
bjos-8676163	25	15	and	and	CCONJ
bjos-8676163	25	16	contribute	contribute	VERB
bjos-8676163	25	17	to	to	ADP
bjos-8676163	25	18	antimicrobial	antimicrobial	ADJ
bjos-8676163	25	19	resistance	resistance	NOUN
bjos-8676163	25	20	.	.	PUNCT
bjos-8676163	26	1	as	as	ADP
bjos-8676163	26	2	an	an	DET
bjos-8676163	26	3	alternative	alternative	ADJ
bjos-8676163	26	4	approach	approach	NOUN
bjos-8676163	26	5	,	,	PUNCT
bjos-8676163	26	6	they	they	PRON
bjos-8676163	26	7	have	have	AUX
bjos-8676163	26	8	been	be	AUX
bjos-8676163	26	9	explored	explore	VERB
bjos-8676163	26	10	in	in	ADP
bjos-8676163	26	11	combination	combination	NOUN
bjos-8676163	26	12	with	with	ADP
bjos-8676163	26	13	conventional	conventional	ADJ
bjos-8676163	26	14	antimicrobials	antimicrobial	NOUN
bjos-8676163	26	15	to	to	PART
bjos-8676163	26	16	investigate	investigate	VERB
bjos-8676163	26	17	potential	potential	ADJ
bjos-8676163	26	18	synergistic	synergistic	ADJ
bjos-8676163	26	19	anti	anti	ADJ
bjos-8676163	26	20	-	-	ADJ
bjos-8676163	26	21	biofilm	biofilm	ADJ
bjos-8676163	26	22	effects4	effects4	PROPN
bjos-8676163	26	23	-	-	PUNCT
bjos-8676163	26	24	6	6	NUM
bjos-8676163	26	25	.	.	PUNCT
bjos-8676163	26	26	by	by	ADP
bjos-8676163	26	27	breaking	break	VERB
bjos-8676163	26	28	down	down	ADP
bjos-8676163	26	29	the	the	DET
bjos-8676163	26	30	eps	eps	PROPN
bjos-8676163	26	31	barrier	barrier	NOUN
bjos-8676163	26	32	,	,	PUNCT
bjos-8676163	26	33	glucanases	glucanase	NOUN
bjos-8676163	26	34	facilitate	facilitate	VERB
bjos-8676163	26	35	the	the	DET
bjos-8676163	26	36	penetration	penetration	NOUN
bjos-8676163	26	37	of	of	ADP
bjos-8676163	26	38	antimicrobials	antimicrobial	NOUN
bjos-8676163	26	39	deeper	deeply	ADV
bjos-8676163	26	40	into	into	ADP
bjos-8676163	26	41	biofilms	biofilm	NOUN
bjos-8676163	26	42	to	to	PART
bjos-8676163	26	43	prevent	prevent	VERB
bjos-8676163	26	44	bacterial	bacterial	ADJ
bjos-8676163	26	45	regrowth	regrowth	NOUN
bjos-8676163	26	46	.	.	PUNCT
bjos-8676163	27	1	however	however	ADV
bjos-8676163	27	2	,	,	PUNCT
bjos-8676163	27	3	it	it	PRON
bjos-8676163	27	4	is	be	AUX
bjos-8676163	27	5	crucial	crucial	ADJ
bjos-8676163	27	6	to	to	PART
bjos-8676163	27	7	consider	consider	VERB
bjos-8676163	27	8	the	the	DET
bjos-8676163	27	9	possible	possible	ADJ
bjos-8676163	27	10	impact	impact	NOUN
bjos-8676163	27	11	of	of	ADP
bjos-8676163	27	12	these	these	DET
bjos-8676163	27	13	enzymes	enzyme	NOUN
bjos-8676163	27	14	on	on	ADP
bjos-8676163	27	15	bacterial	bacterial	ADJ
bjos-8676163	27	16	growth	growth	NOUN
bjos-8676163	27	17	,	,	PUNCT
bjos-8676163	27	18	as	as	SCONJ
bjos-8676163	27	19	they	they	PRON
bjos-8676163	27	20	may	may	AUX
bjos-8676163	27	21	carry	carry	VERB
bjos-8676163	27	22	antimicrobial	antimicrobial	ADJ
bjos-8676163	27	23	compounds	compound	NOUN
bjos-8676163	27	24	from	from	ADP
bjos-8676163	27	25	the	the	DET
bjos-8676163	27	26	microorganisms	microorganism	NOUN
bjos-8676163	27	27	used	use	VERB
bjos-8676163	27	28	for	for	ADP
bjos-8676163	27	29	their	their	PRON
bjos-8676163	27	30	isolation	isolation	NOUN
bjos-8676163	27	31	or	or	CCONJ
bjos-8676163	27	32	other	other	ADJ
bjos-8676163	27	33	impurities	impurity	NOUN
bjos-8676163	27	34	that	that	PRON
bjos-8676163	27	35	could	could	AUX
bjos-8676163	27	36	inhibit	inhibit	VERB
bjos-8676163	27	37	bacterial	bacterial	ADJ
bjos-8676163	27	38	growth	growth	NOUN
bjos-8676163	27	39	,	,	PUNCT
bjos-8676163	27	40	and	and	CCONJ
bjos-8676163	27	41	thus	thus	ADV
bjos-8676163	27	42	result	result	VERB
bjos-8676163	27	43	in	in	ADP
bjos-8676163	27	44	anti	anti	ADJ
bjos-8676163	27	45	-	-	ADJ
bjos-8676163	27	46	biofilm	biofilm	ADJ
bjos-8676163	27	47	effects	effect	NOUN
bjos-8676163	27	48	not	not	PART
bjos-8676163	27	49	solely	solely	ADV
bjos-8676163	27	50	related	relate	VERB
bjos-8676163	27	51	to	to	ADP
bjos-8676163	27	52	the	the	DET
bjos-8676163	27	53	direct	direct	ADJ
bjos-8676163	27	54	activity	activity	NOUN
bjos-8676163	27	55	of	of	ADP
bjos-8676163	27	56	glucanases	glucanase	NOUN
bjos-8676163	27	57	in	in	ADP
bjos-8676163	27	58	degrading	degrade	VERB
bjos-8676163	27	59	eps	ep	NOUN
bjos-8676163	27	60	.	.	PROPN
bjos-8676163	27	61	of	of	ADP
bjos-8676163	27	62	note	note	NOUN
bjos-8676163	27	63	,	,	PUNCT
bjos-8676163	27	64	this	this	DET
bjos-8676163	27	65	aspect	aspect	NOUN
bjos-8676163	27	66	of	of	ADP
bjos-8676163	27	67	glucanase	glucanase	ADJ
bjos-8676163	27	68	activity	activity	NOUN
bjos-8676163	27	69	is	be	AUX
bjos-8676163	27	70	often	often	ADV
bjos-8676163	27	71	overlooked	overlook	VERB
bjos-8676163	27	72	in	in	ADP
bjos-8676163	27	73	studies	study	NOUN
bjos-8676163	27	74	investigating	investigate	VERB
bjos-8676163	27	75	their	their	PRON
bjos-8676163	27	76	efficacy	efficacy	NOUN
bjos-8676163	27	77	as	as	ADP
bjos-8676163	27	78	anti	anti	ADJ
bjos-8676163	27	79	-	-	ADJ
bjos-8676163	27	80	biofilm	biofilm	ADJ
bjos-8676163	27	81	agents4	agents4	NOUN
bjos-8676163	27	82	-	-	SYM
bjos-8676163	27	83	9	9	NUM
bjos-8676163	27	84	.	.	PUNCT
bjos-8676163	28	1	therefore	therefore	ADV
bjos-8676163	28	2	,	,	PUNCT
bjos-8676163	28	3	we	we	PRON
bjos-8676163	28	4	investigated	investigate	VERB
bjos-8676163	28	5	the	the	DET
bjos-8676163	28	6	antimicrobial	antimicrobial	ADJ
bjos-8676163	28	7	activity	activity	NOUN
bjos-8676163	28	8	of	of	ADP
bjos-8676163	28	9	two	two	NUM
bjos-8676163	28	10	newly	newly	ADV
bjos-8676163	28	11	discovered	discover	VERB
bjos-8676163	28	12	glucanases	glucanase	NOUN
bjos-8676163	28	13	characterized	characterize	VERB
bjos-8676163	28	14	by	by	ADP
bjos-8676163	28	15	our	our	PRON
bjos-8676163	28	16	group	group	NOUN
bjos-8676163	28	17	,	,	PUNCT
bjos-8676163	28	18	pmgh87	pmgh87	NOUN
bjos-8676163	28	19	(	(	PUNCT
bjos-8676163	28	20	mutanase	mutanase	PROPN
bjos-8676163	28	21	)	)	PUNCT
bjos-8676163	28	22	from	from	ADP
bjos-8676163	28	23	prevotella	prevotella	NOUN
bjos-8676163	28	24	melaninogenica	melaninogenica	NOUN
bjos-8676163	28	25	and	and	CCONJ
bjos-8676163	28	26	cogh66	cogh66	NOUN
bjos-8676163	28	27	(	(	PUNCT
bjos-8676163	28	28	dextranase	dextranase	NOUN
bjos-8676163	28	29	)	)	PUNCT
bjos-8676163	28	30	from	from	ADP
bjos-8676163	28	31	capnocytophaga	capnocytophaga	PROPN
bjos-8676163	28	32	ochracea	ochracea	PROPN
bjos-8676163	28	33	,	,	PUNCT
bjos-8676163	28	34	using	use	VERB
bjos-8676163	28	35	a	a	DET
bjos-8676163	28	36	commercial	commercial	ADJ
bjos-8676163	28	37	dextranase	dextranase	NOUN
bjos-8676163	28	38	from	from	ADP
bjos-8676163	28	39	penicillum	penicillum	NOUN
bjos-8676163	28	40	sp	sp	NOUN
bjos-8676163	28	41	.	.	PROPN
bjos-8676163	28	42	as	as	ADP
bjos-8676163	28	43	a	a	DET
bjos-8676163	28	44	control	control	NOUN
bjos-8676163	28	45	.	.	PUNCT
bjos-8676163	29	1	previously	previously	ADV
bjos-8676163	29	2	,	,	PUNCT
bjos-8676163	29	3	our	our	PRON
bjos-8676163	29	4	group	group	NOUN
bjos-8676163	29	5	demonstrated	demonstrate	VERB
bjos-8676163	29	6	the	the	DET
bjos-8676163	29	7	potential	potential	NOUN
bjos-8676163	29	8	of	of	ADP
bjos-8676163	29	9	such	such	ADJ
bjos-8676163	29	10	enzymes	enzyme	NOUN
bjos-8676163	29	11	on	on	ADP
bjos-8676163	29	12	s.	s.	PROPN
bjos-8676163	29	13	mutans	mutans	PROPN
bjos-8676163	29	14	biofilm	biofilm	NOUN
bjos-8676163	29	15	inhibition	inhibition	NOUN
bjos-8676163	29	16	and	and	CCONJ
bjos-8676163	29	17	degradation10	degradation10	NOUN
bjos-8676163	29	18	-	-	PUNCT
bjos-8676163	29	19	11	11	NUM
bjos-8676163	29	20	.	.	PUNCT
bjos-8676163	30	1	here	here	ADV
bjos-8676163	30	2	,	,	PUNCT
bjos-8676163	30	3	we	we	PRON
bjos-8676163	30	4	assessed	assess	VERB
bjos-8676163	30	5	the	the	DET
bjos-8676163	30	6	impact	impact	NOUN
bjos-8676163	30	7	of	of	ADP
bjos-8676163	30	8	the	the	DET
bjos-8676163	30	9	enzymes	enzyme	NOUN
bjos-8676163	30	10	on	on	ADP
bjos-8676163	30	11	the	the	DET
bjos-8676163	30	12	growth	growth	NOUN
bjos-8676163	30	13	and	and	CCONJ
bjos-8676163	30	14	metabolism	metabolism	NOUN
bjos-8676163	30	15	of	of	ADP
bjos-8676163	30	16	streptococcus	streptococcus	NOUN
bjos-8676163	30	17	mutans	mutan	NOUN
bjos-8676163	30	18	cultures	culture	NOUN
bjos-8676163	30	19	in	in	ADP
bjos-8676163	30	20	real	real	ADJ
bjos-8676163	30	21	-	-	PUNCT
bjos-8676163	30	22	time	time	NOUN
bjos-8676163	30	23	using	use	VERB
bjos-8676163	30	24	both	both	CCONJ
bjos-8676163	30	25	optical	optical	ADJ
bjos-8676163	30	26	density	density	NOUN
bjos-8676163	30	27	and	and	CCONJ
bjos-8676163	30	28	a	a	DET
bjos-8676163	30	29	luciferase	luciferase	ADJ
bjos-8676163	30	30	ldh	ldh	PROPN
bjos-8676163	30	31	gene	gene	NOUN
bjos-8676163	30	32	reporter	reporter	NOUN
bjos-8676163	30	33	,	,	PUNCT
bjos-8676163	30	34	respectively	respectively	ADV
bjos-8676163	30	35	.	.	PUNCT
bjos-8676163	31	1	material	material	NOUN
bjos-8676163	31	2	and	and	CCONJ
bjos-8676163	31	3	methods	method	NOUN
bjos-8676163	31	4	expression	expression	NOUN
bjos-8676163	31	5	and	and	CCONJ
bjos-8676163	31	6	purification	purification	NOUN
bjos-8676163	31	7	of	of	ADP
bjos-8676163	31	8	cloned	cloned	ADJ
bjos-8676163	31	9	mutanase	mutanase	NOUN
bjos-8676163	31	10	(	(	PUNCT
bjos-8676163	31	11	pmgh87	pmgh87	NOUN
bjos-8676163	31	12	)	)	PUNCT
bjos-8676163	31	13	and	and	CCONJ
bjos-8676163	31	14	dextranase	dextranase	NOUN
bjos-8676163	31	15	(	(	PUNCT
bjos-8676163	31	16	cogh66	cogh66	NOUN
bjos-8676163	31	17	)	)	PUNCT
bjos-8676163	32	1	the	the	DET
bjos-8676163	32	2	nucleotide	nucleotide	ADJ
bjos-8676163	32	3	sequences	sequence	NOUN
bjos-8676163	32	4	encoding	encode	VERB
bjos-8676163	32	5	the	the	DET
bjos-8676163	32	6	gh87	gh87	PROPN
bjos-8676163	32	7	mutanase	mutanase	NOUN
bjos-8676163	32	8	from	from	ADP
bjos-8676163	32	9	prevotella	prevotella	NOUN
bjos-8676163	32	10	melaninogenica	melaninogenica	PROPN
bjos-8676163	32	11	(	(	PUNCT
bjos-8676163	32	12	pmgh87	pmgh87	PROPN
bjos-8676163	32	13	)	)	PUNCT
bjos-8676163	32	14	(	(	PUNCT
bjos-8676163	32	15	genbank	genbank	PROPN
bjos-8676163	32	16	i	i	PROPN
bjos-8676163	32	17	d	d	PROPN
bjos-8676163	32	18	:	:	PUNCT
bjos-8676163	32	19	wp_004358976.1	wp_004358976.1	PROPN
bjos-8676163	32	20	)	)	PUNCT
bjos-8676163	32	21	and	and	CCONJ
bjos-8676163	32	22	the	the	DET
bjos-8676163	32	23	gh66	gh66	PROPN
bjos-8676163	32	24	dextranase	dextranase	NOUN
bjos-8676163	32	25	from	from	ADP
bjos-8676163	32	26	capnocytophaga	capnocytophaga	PROPN
bjos-8676163	32	27	ochracea	ochracea	PROPN
bjos-8676163	32	28	(	(	PUNCT
bjos-8676163	32	29	cogh66	cogh66	PROPN
bjos-8676163	32	30	)	)	PUNCT
bjos-8676163	32	31	(	(	PUNCT
bjos-8676163	32	32	genbank	genbank	PROPN
bjos-8676163	32	33	i	i	PROPN
bjos-8676163	32	34	d	d	PROPN
bjos-8676163	32	35	:	:	PUNCT
bjos-8676163	32	36	wp_128091406.1	wp_128091406.1	VERB
bjos-8676163	32	37	)	)	PUNCT
bjos-8676163	32	38	were	be	AUX
bjos-8676163	32	39	amplified	amplify	VERB
bjos-8676163	32	40	from	from	ADP
bjos-8676163	32	41	the	the	DET
bjos-8676163	32	42	respective	respective	ADJ
bjos-8676163	32	43	genomic	genomic	NOUN
bjos-8676163	32	44	dna	dna	NOUN
bjos-8676163	32	45	and	and	CCONJ
bjos-8676163	32	46	cloned	clone	VERB
bjos-8676163	32	47	,	,	PUNCT
bjos-8676163	32	48	as	as	SCONJ
bjos-8676163	32	49	previously	previously	ADV
bjos-8676163	32	50	described	describe	VERB
bjos-8676163	32	51	by	by	ADP
bjos-8676163	32	52	cortez	cortez	PROPN
bjos-8676163	32	53	et	et	PROPN
bjos-8676163	32	54	al.10	al.10	PROPN
bjos-8676163	32	55	(	(	PUNCT
bjos-8676163	32	56	2023	2023	NUM
bjos-8676163	32	57	)	)	PUNCT
bjos-8676163	32	58	.	.	PUNCT
bjos-8676163	33	1	heterologous	heterologous	ADJ
bjos-8676163	33	2	protein	protein	NOUN
bjos-8676163	33	3	expression	expression	NOUN
bjos-8676163	33	4	was	be	AUX
bjos-8676163	33	5	performed	perform	VERB
bjos-8676163	33	6	in	in	ADP
bjos-8676163	33	7	luria	luria	NOUN
bjos-8676163	33	8	-	-	PUNCT
bjos-8676163	33	9	bertani	bertani	NOUN
bjos-8676163	33	10	(	(	PUNCT
bjos-8676163	33	11	lb	lb	NOUN
bjos-8676163	33	12	)	)	PUNCT
bjos-8676163	33	13	broth	broth	NOUN
bjos-8676163	33	14	containing	contain	VERB
bjos-8676163	33	15	50	50	NUM
bjos-8676163	33	16	μg	μg	NOUN
bjos-8676163	33	17	/	/	SYM
bjos-8676163	33	18	ml	ml	PROPN
bjos-8676163	33	19	of	of	ADP
bjos-8676163	33	20	kanamycin	kanamycin	NOUN
bjos-8676163	33	21	at	at	ADP
bjos-8676163	33	22	37	37	NUM
bjos-8676163	33	23	°	°	ADP
bjos-8676163	33	24	c	c	NOUN
bjos-8676163	33	25	and	and	CCONJ
bjos-8676163	33	26	180	180	NUM
bjos-8676163	33	27	rpm	rpm	NOUN
bjos-8676163	33	28	until	until	ADP
bjos-8676163	33	29	od	od	PROPN
bjos-8676163	33	30	0.6	0.6	NUM
bjos-8676163	33	31	3	3	NUM
bjos-8676163	33	32	queiroz	queiroz	ADV
bjos-8676163	33	33	et	et	PROPN
bjos-8676163	34	1	al	al	PROPN
bjos-8676163	34	2	.	.	PROPN
bjos-8676163	34	3	braz	braz	PROPN
bjos-8676163	34	4	j	j	PROPN
bjos-8676163	34	5	oral	oral	PROPN
bjos-8676163	34	6	sci	sci	PROPN
bjos-8676163	34	7	.	.	PUNCT
bjos-8676163	35	1	2024;23	2024;23	NUM
bjos-8676163	35	2	:	:	PUNCT
bjos-8676163	35	3	e246163	e246163	NOUN
bjos-8676163	35	4	(	(	PUNCT
bjos-8676163	35	5	600	600	NUM
bjos-8676163	35	6	nm	nm	NOUN
bjos-8676163	35	7	)	)	PUNCT
bjos-8676163	35	8	followed	follow	VERB
bjos-8676163	35	9	by	by	ADP
bjos-8676163	35	10	induction	induction	NOUN
bjos-8676163	35	11	with	with	ADP
bjos-8676163	35	12	1	1	NUM
bjos-8676163	35	13	mm	mm	NOUN
bjos-8676163	35	14	iptg	iptg	NOUN
bjos-8676163	35	15	at	at	ADP
bjos-8676163	35	16	18	18	NUM
bjos-8676163	35	17	°	°	ADP
bjos-8676163	35	18	c	c	NOUN
bjos-8676163	35	19	for	for	ADP
bjos-8676163	35	20	approximately	approximately	ADV
bjos-8676163	35	21	16	16	NUM
bjos-8676163	35	22	h.	h.	NOUN
bjos-8676163	35	23	then	then	ADV
bjos-8676163	35	24	,	,	PUNCT
bjos-8676163	35	25	the	the	DET
bjos-8676163	35	26	cells	cell	NOUN
bjos-8676163	35	27	were	be	AUX
bjos-8676163	35	28	harvested	harvest	VERB
bjos-8676163	35	29	by	by	ADP
bjos-8676163	35	30	centrifugation	centrifugation	NOUN
bjos-8676163	35	31	and	and	CCONJ
bjos-8676163	35	32	resuspended	resuspend	VERB
bjos-8676163	35	33	in	in	ADP
bjos-8676163	35	34	50	50	NUM
bjos-8676163	35	35	mm	mm	NOUN
bjos-8676163	35	36	tris	tris	PROPN
bjos-8676163	35	37	-	-	PUNCT
bjos-8676163	35	38	hcl	hcl	PROPN
bjos-8676163	35	39	(	(	PUNCT
bjos-8676163	35	40	ph	ph	PROPN
bjos-8676163	35	41	8.0	8.0	NUM
bjos-8676163	35	42	)	)	PUNCT
bjos-8676163	35	43	,	,	PUNCT
bjos-8676163	35	44	200	200	NUM
bjos-8676163	35	45	mm	mm	NOUN
bjos-8676163	35	46	nacl	nacl	NOUN
bjos-8676163	35	47	,	,	PUNCT
bjos-8676163	35	48	1	1	NUM
bjos-8676163	35	49	mm	mm	NOUN
bjos-8676163	35	50	pmsf	pmsf	NOUN
bjos-8676163	35	51	buffer	buffer	NOUN
bjos-8676163	35	52	and	and	CCONJ
bjos-8676163	35	53	stored	store	VERB
bjos-8676163	35	54	at	at	ADP
bjos-8676163	35	55	4	4	NUM
bjos-8676163	35	56	°	°	NOUN
bjos-8676163	35	57	c	c	NOUN
bjos-8676163	35	58	before	before	ADP
bjos-8676163	35	59	purification	purification	NOUN
bjos-8676163	35	60	.	.	PUNCT
bjos-8676163	36	1	purification	purification	NOUN
bjos-8676163	36	2	of	of	ADP
bjos-8676163	36	3	expressed	express	VERB
bjos-8676163	36	4	mutanase	mutanase	NOUN
bjos-8676163	36	5	(	(	PUNCT
bjos-8676163	36	6	pmgh87	pmgh87	NOUN
bjos-8676163	36	7	)	)	PUNCT
bjos-8676163	36	8	and	and	CCONJ
bjos-8676163	36	9	dextranase	dextranase	NOUN
bjos-8676163	36	10	(	(	PUNCT
bjos-8676163	36	11	cogh66	cogh66	NOUN
bjos-8676163	36	12	)	)	PUNCT
bjos-8676163	36	13	enzyme	enzyme	NOUN
bjos-8676163	36	14	purification	purification	NOUN
bjos-8676163	36	15	was	be	AUX
bjos-8676163	36	16	carried	carry	VERB
bjos-8676163	36	17	out	out	ADP
bjos-8676163	36	18	following	follow	VERB
bjos-8676163	36	19	the	the	DET
bjos-8676163	36	20	protocol	protocol	NOUN
bjos-8676163	36	21	described	describe	VERB
bjos-8676163	36	22	by	by	ADP
bjos-8676163	36	23	camilo	camilo	PROPN
bjos-8676163	36	24	and	and	CCONJ
bjos-8676163	36	25	polikarpov12	polikarpov12	ADJ
bjos-8676163	36	26	(	(	PUNCT
bjos-8676163	36	27	2014	2014	NUM
bjos-8676163	36	28	)	)	PUNCT
bjos-8676163	36	29	.	.	PUNCT
bjos-8676163	37	1	briefly	briefly	NOUN
bjos-8676163	37	2	,	,	PUNCT
bjos-8676163	37	3	the	the	DET
bjos-8676163	37	4	resuspended	resuspend	VERB
bjos-8676163	37	5	cells	cell	NOUN
bjos-8676163	37	6	were	be	AUX
bjos-8676163	37	7	disrupted	disrupt	VERB
bjos-8676163	37	8	performing	perform	VERB
bjos-8676163	37	9	six	six	NUM
bjos-8676163	37	10	cycles	cycle	NOUN
bjos-8676163	37	11	of	of	ADP
bjos-8676163	37	12	sonication	sonication	NOUN
bjos-8676163	37	13	on	on	ADP
bjos-8676163	37	14	ice	ice	NOUN
bjos-8676163	37	15	bath	bath	NOUN
bjos-8676163	37	16	using	use	VERB
bjos-8676163	37	17	a	a	DET
bjos-8676163	37	18	sonic	sonic	ADJ
bjos-8676163	37	19	dismembrator	dismembrator	NOUN
bjos-8676163	37	20	sonifier	sonifier	NOUN
bjos-8676163	37	21	(	(	PUNCT
bjos-8676163	37	22	fisher	fisher	PROPN
bjos-8676163	37	23	scientific	scientific	PROPN
bjos-8676163	37	24	,	,	PUNCT
bjos-8676163	37	25	hampton	hampton	PROPN
bjos-8676163	37	26	,	,	PUNCT
bjos-8676163	37	27	usa	usa	PROPN
bjos-8676163	37	28	)	)	PUNCT
bjos-8676163	37	29	at	at	ADP
bjos-8676163	37	30	40	40	NUM
bjos-8676163	37	31	%	%	NOUN
bjos-8676163	37	32	amplitude	amplitude	NOUN
bjos-8676163	37	33	.	.	PUNCT
bjos-8676163	38	1	the	the	DET
bjos-8676163	38	2	resulting	result	VERB
bjos-8676163	38	3	lysate	lysate	NOUN
bjos-8676163	38	4	was	be	AUX
bjos-8676163	38	5	then	then	ADV
bjos-8676163	38	6	clarified	clarify	VERB
bjos-8676163	38	7	by	by	ADP
bjos-8676163	38	8	centrifugation	centrifugation	NOUN
bjos-8676163	38	9	at	at	ADP
bjos-8676163	38	10	20,200	20,200	NUM
bjos-8676163	38	11	x	x	SYM
bjos-8676163	38	12	g	g	NOUN
bjos-8676163	38	13	at	at	ADP
bjos-8676163	38	14	4	4	NUM
bjos-8676163	38	15	°	°	ADP
bjos-8676163	38	16	c	c	NOUN
bjos-8676163	38	17	for	for	SCONJ
bjos-8676163	38	18	30	30	NUM
bjos-8676163	38	19	min	min	NOUN
bjos-8676163	38	20	to	to	PART
bjos-8676163	38	21	remove	remove	VERB
bjos-8676163	38	22	cell	cell	NOUN
bjos-8676163	38	23	debris	debris	NOUN
bjos-8676163	38	24	,	,	PUNCT
bjos-8676163	38	25	and	and	CCONJ
bjos-8676163	38	26	the	the	DET
bjos-8676163	38	27	resulting	result	VERB
bjos-8676163	38	28	supernatant	supernatant	NOUN
bjos-8676163	38	29	was	be	AUX
bjos-8676163	38	30	used	use	VERB
bjos-8676163	38	31	for	for	ADP
bjos-8676163	38	32	mutanase	mutanase	NOUN
bjos-8676163	38	33	or	or	CCONJ
bjos-8676163	38	34	dextranase	dextranase	ADJ
bjos-8676163	38	35	purification	purification	NOUN
bjos-8676163	38	36	.	.	PUNCT
bjos-8676163	39	1	the	the	DET
bjos-8676163	39	2	supernatant	supernatant	NOUN
bjos-8676163	39	3	from	from	ADP
bjos-8676163	39	4	each	each	DET
bjos-8676163	39	5	sample	sample	NOUN
bjos-8676163	39	6	was	be	AUX
bjos-8676163	39	7	loaded	load	VERB
bjos-8676163	39	8	in	in	ADP
bjos-8676163	39	9	a	a	DET
bjos-8676163	39	10	column	column	NOUN
bjos-8676163	39	11	containing	contain	VERB
bjos-8676163	39	12	ni	ni	PROPN
bjos-8676163	39	13	-	-	PUNCT
bjos-8676163	39	14	nta	nta	PROPN
bjos-8676163	39	15	superflow	superflow	NOUN
bjos-8676163	39	16	resin	resin	NOUN
bjos-8676163	39	17	(	(	PUNCT
bjos-8676163	39	18	qiagen	qiagen	PROPN
bjos-8676163	39	19	,	,	PUNCT
bjos-8676163	39	20	hilden	hilden	PROPN
bjos-8676163	39	21	,	,	PUNCT
bjos-8676163	39	22	germany	germany	PROPN
bjos-8676163	39	23	)	)	PUNCT
bjos-8676163	39	24	,	,	PUNCT
bjos-8676163	39	25	previously	previously	ADV
bjos-8676163	39	26	equilibrated	equilibrate	VERB
bjos-8676163	39	27	with	with	ADP
bjos-8676163	39	28	50	50	NUM
bjos-8676163	39	29	mm	mm	NUM
bjos-8676163	39	30	tris	tris	PROPN
bjos-8676163	39	31	-	-	PUNCT
bjos-8676163	39	32	hcl	hcl	PROPN
bjos-8676163	39	33	(	(	PUNCT
bjos-8676163	39	34	ph	ph	PROPN
bjos-8676163	39	35	8.0	8.0	NUM
bjos-8676163	39	36	)	)	PUNCT
bjos-8676163	39	37	and	and	CCONJ
bjos-8676163	39	38	200	200	NUM
bjos-8676163	39	39	mm	mm	PROPN
bjos-8676163	39	40	nacl	nacl	NOUN
bjos-8676163	39	41	buffer	buffer	NOUN
bjos-8676163	39	42	.	.	PUNCT
bjos-8676163	40	1	elution	elution	NOUN
bjos-8676163	40	2	was	be	AUX
bjos-8676163	40	3	performed	perform	VERB
bjos-8676163	40	4	using	use	VERB
bjos-8676163	40	5	an	an	DET
bjos-8676163	40	6	imidazole	imidazole	NOUN
bjos-8676163	40	7	gradient	gradient	NOUN
bjos-8676163	40	8	.	.	PUNCT
bjos-8676163	41	1	the	the	DET
bjos-8676163	41	2	resulting	result	VERB
bjos-8676163	41	3	eluted	eluted	ADJ
bjos-8676163	41	4	protein	protein	NOUN
bjos-8676163	41	5	fractions	fraction	NOUN
bjos-8676163	41	6	were	be	AUX
bjos-8676163	41	7	combined	combine	VERB
bjos-8676163	41	8	and	and	CCONJ
bjos-8676163	41	9	concentrated	concentrate	VERB
bjos-8676163	41	10	using	use	VERB
bjos-8676163	41	11	a	a	DET
bjos-8676163	41	12	50	50	NUM
bjos-8676163	41	13	kda	kda	NOUN
bjos-8676163	41	14	molecular	molecular	ADJ
bjos-8676163	41	15	cut	cut	VERB
bjos-8676163	41	16	-	-	PUNCT
bjos-8676163	41	17	off	off	ADP
bjos-8676163	41	18	concentrator	concentrator	NOUN
bjos-8676163	41	19	to	to	PART
bjos-8676163	41	20	reduce	reduce	VERB
bjos-8676163	41	21	imidazole	imidazole	NOUN
bjos-8676163	41	22	concentration	concentration	NOUN
bjos-8676163	41	23	to	to	ADP
bjos-8676163	41	24	less	less	ADJ
bjos-8676163	41	25	than	than	ADP
bjos-8676163	41	26	20	20	NUM
bjos-8676163	41	27	mm	mm	NOUN
bjos-8676163	41	28	.	.	PUNCT
bjos-8676163	42	1	the	the	DET
bjos-8676163	42	2	resultant	resultant	NOUN
bjos-8676163	42	3	sample	sample	NOUN
bjos-8676163	42	4	was	be	AUX
bjos-8676163	42	5	incubated	incubate	VERB
bjos-8676163	42	6	with	with	ADP
bjos-8676163	42	7	recombinant	recombinant	ADJ
bjos-8676163	42	8	tev	tev	NOUN
bjos-8676163	42	9	protease	protease	NOUN
bjos-8676163	42	10	at	at	ADP
bjos-8676163	42	11	4	4	NUM
bjos-8676163	42	12	°	°	ADP
bjos-8676163	42	13	c	c	NOUN
bjos-8676163	42	14	for	for	ADP
bjos-8676163	42	15	16	16	NUM
bjos-8676163	42	16	h	h	NOUN
bjos-8676163	42	17	for	for	ADP
bjos-8676163	42	18	6xhis	6xhis	PROPN
bjos-8676163	42	19	-	-	PUNCT
bjos-8676163	42	20	thioredoxin	thioredoxin	PROPN
bjos-8676163	42	21	tag	tag	NOUN
bjos-8676163	42	22	removal	removal	NOUN
bjos-8676163	42	23	from	from	ADP
bjos-8676163	42	24	the	the	DET
bjos-8676163	42	25	target	target	NOUN
bjos-8676163	42	26	enzyme	enzyme	NOUN
bjos-8676163	42	27	.	.	PUNCT
bjos-8676163	43	1	finally	finally	ADV
bjos-8676163	43	2	,	,	PUNCT
bjos-8676163	43	3	a	a	DET
bjos-8676163	43	4	second	second	ADJ
bjos-8676163	43	5	ni²+	ni²+	PROPN
bjos-8676163	43	6	affinity	affinity	NOUN
bjos-8676163	43	7	chromatographic	chromatographic	ADJ
bjos-8676163	43	8	step	step	NOUN
bjos-8676163	43	9	was	be	AUX
bjos-8676163	43	10	used	use	VERB
bjos-8676163	43	11	for	for	ADP
bjos-8676163	43	12	separation	separation	NOUN
bjos-8676163	43	13	of	of	ADP
bjos-8676163	43	14	tag	tag	NOUN
bjos-8676163	43	15	-	-	PUNCT
bjos-8676163	43	16	free	free	ADJ
bjos-8676163	43	17	mutanase	mutanase	NOUN
bjos-8676163	43	18	or	or	CCONJ
bjos-8676163	43	19	dextranase	dextranase	NOUN
bjos-8676163	43	20	from	from	ADP
bjos-8676163	43	21	contaminants	contaminant	NOUN
bjos-8676163	43	22	and	and	CCONJ
bjos-8676163	43	23	tev	tev	NOUN
bjos-8676163	43	24	protease	protease	NOUN
bjos-8676163	43	25	.	.	PUNCT
bjos-8676163	44	1	the	the	DET
bjos-8676163	44	2	protein	protein	NOUN
bjos-8676163	44	3	sample	sample	NOUN
bjos-8676163	44	4	’s	’s	PART
bjos-8676163	44	5	purity	purity	NOUN
bjos-8676163	44	6	was	be	AUX
bjos-8676163	44	7	confirmed	confirm	VERB
bjos-8676163	44	8	by	by	ADP
bjos-8676163	44	9	sodium	sodium	NOUN
bjos-8676163	44	10	dodecyl	dodecyl	PROPN
bjos-8676163	44	11	sulfate	sulfate	NOUN
bjos-8676163	44	12	polyacrylamide	polyacrylamide	NOUN
bjos-8676163	44	13	gel	gel	NOUN
bjos-8676163	44	14	electrophoresis	electrophoresis	NOUN
bjos-8676163	44	15	(	(	PUNCT
bjos-8676163	44	16	sds	sds	NOUN
bjos-8676163	44	17	-	-	PUNCT
bjos-8676163	44	18	page	page	NOUN
bjos-8676163	44	19	)	)	PUNCT
bjos-8676163	44	20	under	under	ADP
bjos-8676163	44	21	denaturing	denature	VERB
bjos-8676163	44	22	conditions	condition	NOUN
bjos-8676163	44	23	.	.	PUNCT
bjos-8676163	45	1	the	the	DET
bjos-8676163	45	2	purified	purified	ADJ
bjos-8676163	45	3	enzymes	enzyme	NOUN
bjos-8676163	45	4	were	be	AUX
bjos-8676163	45	5	freeze	freeze	NOUN
bjos-8676163	45	6	-	-	PUNCT
bjos-8676163	45	7	dried	dry	VERB
bjos-8676163	45	8	and	and	CCONJ
bjos-8676163	45	9	,	,	PUNCT
bjos-8676163	45	10	previously	previously	ADV
bjos-8676163	45	11	to	to	PART
bjos-8676163	45	12	start	start	VERB
bjos-8676163	45	13	the	the	DET
bjos-8676163	45	14	biofilm	biofilm	NOUN
bjos-8676163	45	15	assay	assay	VERB
bjos-8676163	45	16	,	,	PUNCT
bjos-8676163	45	17	enzymes	enzyme	NOUN
bjos-8676163	45	18	were	be	AUX
bjos-8676163	45	19	resuspended	resuspend	VERB
bjos-8676163	45	20	phosphate	phosphate	ADJ
bjos-8676163	45	21	-	-	PUNCT
bjos-8676163	45	22	buffer	buffer	NOUN
bjos-8676163	45	23	salive	salive	NOUN
bjos-8676163	45	24	(	(	PUNCT
bjos-8676163	45	25	pbs	pbs	PROPN
bjos-8676163	45	26	)	)	PUNCT
bjos-8676163	45	27	solution	solution	NOUN
bjos-8676163	45	28	1	1	NUM
bjos-8676163	45	29	x	x	NOUN
bjos-8676163	45	30	,	,	PUNCT
bjos-8676163	45	31	ph	ph	PROPN
bjos-8676163	45	32	8.0	8.0	NUM
bjos-8676163	45	33	.	.	PUNCT
bjos-8676163	46	1	the	the	DET
bjos-8676163	46	2	concentration	concentration	NOUN
bjos-8676163	46	3	was	be	AUX
bjos-8676163	46	4	determined	determine	VERB
bjos-8676163	46	5	using	use	VERB
bjos-8676163	46	6	nanodrop	nanodrop	NOUN
bjos-8676163	46	7	1000	1000	NUM
bjos-8676163	46	8	spectrophotometer	spectrophotometer	NOUN
bjos-8676163	46	9	(	(	PUNCT
bjos-8676163	46	10	thermo	thermo	NOUN
bjos-8676163	46	11	scientific	scientific	NOUN
bjos-8676163	46	12	,	,	PUNCT
bjos-8676163	46	13	waltham	waltham	PROPN
bjos-8676163	46	14	,	,	PUNCT
bjos-8676163	46	15	eua	eua	PROPN
bjos-8676163	46	16	)	)	PUNCT
bjos-8676163	46	17	,	,	PUNCT
bjos-8676163	46	18	measuring	measure	VERB
bjos-8676163	46	19	absorbance	absorbance	NOUN
bjos-8676163	46	20	at	at	ADP
bjos-8676163	46	21	280	280	NUM
bjos-8676163	46	22	nm	nm	NOUN
bjos-8676163	46	23	and	and	CCONJ
bjos-8676163	46	24	applying	apply	VERB
bjos-8676163	46	25	the	the	DET
bjos-8676163	46	26	calculated	calculate	VERB
bjos-8676163	46	27	extinction	extinction	NOUN
bjos-8676163	46	28	coefficient	coefficient	NOUN
bjos-8676163	46	29	(	(	PUNCT
bjos-8676163	46	30	ɛ	ɛ	PROPN
bjos-8676163	46	31	=	=	SYM
bjos-8676163	46	32	165180	165180	NUM
bjos-8676163	46	33	m−1	m−1	PROPN
bjos-8676163	46	34	cm−1	cm−1	NOUN
bjos-8676163	46	35	for	for	ADP
bjos-8676163	46	36	mutanase	mutanase	NOUN
bjos-8676163	46	37	and	and	CCONJ
bjos-8676163	47	1	ɛ	ɛ	PROPN
bjos-8676163	47	2	=	=	NOUN
bjos-8676163	47	3	122000	122000	NUM
bjos-8676163	48	1	m−1	m−1	PROPN
bjos-8676163	48	2	cm−1	cm−1	NOUN
bjos-8676163	48	3	for	for	ADP
bjos-8676163	48	4	dextranase)12	dextranase)12	NOUN
bjos-8676163	48	5	.	.	PUNCT
bjos-8676163	49	1	experimental	experimental	ADJ
bjos-8676163	49	2	treatments	treatment	NOUN
bjos-8676163	49	3	in	in	ADP
bjos-8676163	49	4	addition	addition	NOUN
bjos-8676163	49	5	to	to	ADP
bjos-8676163	49	6	mutanase	mutanase	PROPN
bjos-8676163	49	7	(	(	PUNCT
bjos-8676163	49	8	pmgh87	pmgh87	NOUN
bjos-8676163	49	9	)	)	PUNCT
bjos-8676163	49	10	from	from	ADP
bjos-8676163	49	11	prevotella	prevotella	NOUN
bjos-8676163	49	12	melaninogenica	melaninogenica	NOUN
bjos-8676163	49	13	and	and	CCONJ
bjos-8676163	49	14	dextranase	dextranase	NOUN
bjos-8676163	49	15	(	(	PUNCT
bjos-8676163	49	16	cogh66	cogh66	NOUN
bjos-8676163	49	17	)	)	PUNCT
bjos-8676163	49	18	from	from	ADP
bjos-8676163	49	19	capnocytophaga	capnocytophaga	PROPN
bjos-8676163	49	20	ochracea	ochracea	PROPN
bjos-8676163	49	21	,	,	PUNCT
bjos-8676163	49	22	both	both	PRON
bjos-8676163	49	23	of	of	ADP
bjos-8676163	49	24	which	which	PRON
bjos-8676163	49	25	were	be	AUX
bjos-8676163	49	26	expressed	express	VERB
bjos-8676163	49	27	and	and	CCONJ
bjos-8676163	49	28	purified	purify	VERB
bjos-8676163	49	29	,	,	PUNCT
bjos-8676163	49	30	a	a	DET
bjos-8676163	49	31	commercially	commercially	ADV
bjos-8676163	49	32	available	available	ADJ
bjos-8676163	49	33	dextranase	dextranase	NOUN
bjos-8676163	49	34	(	(	PUNCT
bjos-8676163	49	35	α-(1→6	α-(1→6	NOUN
bjos-8676163	49	36	)	)	PUNCT
bjos-8676163	49	37	glucanase	glucanase	NOUN
bjos-8676163	49	38	,	,	PUNCT
bjos-8676163	49	39	ec3.2.1.11	ec3.2.1.11	PROPN
bjos-8676163	49	40	,	,	PUNCT
bjos-8676163	49	41	from	from	ADP
bjos-8676163	49	42	penicillium	penicillium	NOUN
bjos-8676163	49	43	sp	sp	PROPN
bjos-8676163	49	44	.	.	PUNCT
bjos-8676163	49	45	;	;	PUNCT
bjos-8676163	49	46	product	product	NOUN
bjos-8676163	49	47	number	number	NOUN
bjos-8676163	49	48	:	:	PUNCT
bjos-8676163	49	49	d4668	d4668	NOUN
bjos-8676163	49	50	-	-	PUNCT
bjos-8676163	49	51	1ku	1ku	NOUN
bjos-8676163	49	52	;	;	PUNCT
bjos-8676163	49	53	batch	batch	NOUN
bjos-8676163	49	54	number	number	NOUN
bjos-8676163	49	55	:	:	PUNCT
bjos-8676163	49	56	0000136817	0000136817	NUM
bjos-8676163	49	57	)	)	PUNCT
bjos-8676163	49	58	was	be	AUX
bjos-8676163	49	59	evaluated	evaluate	VERB
bjos-8676163	49	60	as	as	ADP
bjos-8676163	49	61	control	control	NOUN
bjos-8676163	49	62	.	.	PUNCT
bjos-8676163	50	1	the	the	DET
bjos-8676163	50	2	three	three	NUM
bjos-8676163	50	3	enzymes	enzyme	NOUN
bjos-8676163	50	4	were	be	AUX
bjos-8676163	50	5	also	also	ADV
bjos-8676163	50	6	evaluated	evaluate	VERB
bjos-8676163	50	7	in	in	ADP
bjos-8676163	50	8	their	their	PRON
bjos-8676163	50	9	denatured	denature	VERB
bjos-8676163	50	10	form	form	NOUN
bjos-8676163	50	11	by	by	ADP
bjos-8676163	50	12	heating	heat	VERB
bjos-8676163	50	13	them	they	PRON
bjos-8676163	50	14	at	at	ADP
bjos-8676163	50	15	100	100	NUM
bjos-8676163	50	16	°	°	ADP
bjos-8676163	50	17	c	c	NOUN
bjos-8676163	50	18	for	for	ADP
bjos-8676163	50	19	15	15	NUM
bjos-8676163	50	20	min10	min10	PROPN
bjos-8676163	50	21	.	.	PUNCT
bjos-8676163	51	1	the	the	DET
bjos-8676163	51	2	antimicrobial	antimicrobial	ADJ
bjos-8676163	51	3	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	51	4	digluconate	digluconate	NOUN
bjos-8676163	51	5	(	(	PUNCT
bjos-8676163	51	6	chx	chx	PROPN
bjos-8676163	51	7	)	)	PUNCT
bjos-8676163	51	8	,	,	PUNCT
bjos-8676163	51	9	commonly	commonly	ADV
bjos-8676163	51	10	used	use	VERB
bjos-8676163	51	11	in	in	ADP
bjos-8676163	51	12	mouthwash	mouthwash	NOUN
bjos-8676163	51	13	,	,	PUNCT
bjos-8676163	51	14	was	be	AUX
bjos-8676163	51	15	used	use	VERB
bjos-8676163	51	16	as	as	ADP
bjos-8676163	51	17	the	the	DET
bjos-8676163	51	18	positive	positive	ADJ
bjos-8676163	51	19	control	control	NOUN
bjos-8676163	51	20	,	,	PUNCT
bjos-8676163	51	21	while	while	SCONJ
bjos-8676163	51	22	only	only	ADV
bjos-8676163	51	23	pure	pure	ADJ
bjos-8676163	51	24	cdm	cdm	PROPN
bjos-8676163	51	25	medium	medium	NOUN
bjos-8676163	51	26	as	as	ADP
bjos-8676163	51	27	the	the	DET
bjos-8676163	51	28	negative	negative	ADJ
bjos-8676163	51	29	control	control	NOUN
bjos-8676163	51	30	.	.	PUNCT
bjos-8676163	52	1	bacterial	bacterial	ADJ
bjos-8676163	52	2	growth	growth	NOUN
bjos-8676163	52	3	and	and	CCONJ
bjos-8676163	52	4	luciferase	luciferase	VERB
bjos-8676163	52	5	reporter	reporter	NOUN
bjos-8676163	52	6	bioassay	bioassay	PROPN
bjos-8676163	52	7	lactate	lactate	PROPN
bjos-8676163	52	8	dehydrogenase	dehydrogenase	PROPN
bjos-8676163	52	9	(	(	PUNCT
bjos-8676163	52	10	ldh	ldh	PROPN
bjos-8676163	52	11	)	)	PUNCT
bjos-8676163	52	12	gene	gene	NOUN
bjos-8676163	52	13	is	be	AUX
bjos-8676163	52	14	constitutive	constitutive	ADJ
bjos-8676163	52	15	in	in	ADP
bjos-8676163	52	16	streptococci	streptococci	NOUN
bjos-8676163	52	17	and	and	CCONJ
bjos-8676163	52	18	plays	play	VERB
bjos-8676163	52	19	a	a	DET
bjos-8676163	52	20	crucial	crucial	ADJ
bjos-8676163	52	21	role	role	NOUN
bjos-8676163	52	22	in	in	ADP
bjos-8676163	52	23	the	the	DET
bjos-8676163	52	24	atp	atp	NOUN
bjos-8676163	52	25	-	-	PUNCT
bjos-8676163	52	26	generating	generate	VERB
bjos-8676163	52	27	pathway	pathway	NOUN
bjos-8676163	52	28	,	,	PUNCT
bjos-8676163	52	29	providing	provide	VERB
bjos-8676163	52	30	information	information	NOUN
bjos-8676163	52	31	into	into	ADP
bjos-8676163	52	32	both	both	DET
bjos-8676163	52	33	viability	viability	NOUN
bjos-8676163	52	34	and	and	CCONJ
bjos-8676163	52	35	metabolic	metabolic	NOUN
bjos-8676163	52	36	status13	status13	NOUN
bjos-8676163	52	37	.	.	PUNCT
bjos-8676163	53	1	in	in	ADP
bjos-8676163	53	2	this	this	DET
bjos-8676163	53	3	study	study	NOUN
bjos-8676163	53	4	,	,	PUNCT
bjos-8676163	53	5	an	an	DET
bjos-8676163	53	6	isogenic	isogenic	ADJ
bjos-8676163	53	7	mutant	mutant	ADJ
bjos-8676163	53	8	strain	strain	NOUN
bjos-8676163	53	9	of	of	ADP
bjos-8676163	53	10	streptococcus	streptococcus	NOUN
bjos-8676163	53	11	mutans	mutan	NOUN
bjos-8676163	53	12	ua159	ua159	PROPN
bjos-8676163	53	13	containing	contain	VERB
bjos-8676163	53	14	a	a	DET
bjos-8676163	53	15	luciferase	luciferase	ADJ
bjos-8676163	53	16	reporter	reporter	NOUN
bjos-8676163	53	17	for	for	ADP
bjos-8676163	53	18	ldh	ldh	PROPN
bjos-8676163	53	19	gene	gene	NOUN
bjos-8676163	53	20	(	(	PUNCT
bjos-8676163	53	21	designated	designate	VERB
bjos-8676163	53	22	as	as	ADP
bjos-8676163	53	23	sm120	sm120	ADJ
bjos-8676163	53	24	)	)	PUNCT
bjos-8676163	53	25	as	as	SCONJ
bjos-8676163	53	26	described	describe	VERB
bjos-8676163	53	27	by	by	ADP
bjos-8676163	53	28	dornelas	dornela	NOUN
bjos-8676163	53	29	-	-	PUNCT
bjos-8676163	53	30	figueira	figueira	PROPN
bjos-8676163	53	31	et	et	PROPN
bjos-8676163	53	32	al.14	al.14	PROPN
bjos-8676163	53	33	(	(	PUNCT
bjos-8676163	53	34	2023	2023	NUM
bjos-8676163	53	35	)	)	PUNCT
bjos-8676163	53	36	,	,	PUNCT
bjos-8676163	53	37	was	be	AUX
bjos-8676163	53	38	used	use	VERB
bjos-8676163	53	39	in	in	ADP
bjos-8676163	53	40	the	the	DET
bjos-8676163	53	41	bioassay	bioassay	NOUN
bjos-8676163	53	42	.	.	PUNCT
bjos-8676163	54	1	briefly	briefly	ADV
bjos-8676163	54	2	,	,	PUNCT
bjos-8676163	54	3	bacterial	bacterial	ADJ
bjos-8676163	54	4	inoculum	inoculum	NOUN
bjos-8676163	54	5	of	of	ADP
bjos-8676163	54	6	s.	s.	PROPN
bjos-8676163	54	7	mutans	mutans	PROPN
bjos-8676163	54	8	sm120	sm120	PROPN
bjos-8676163	54	9	was	be	AUX
bjos-8676163	54	10	prepared	prepare	VERB
bjos-8676163	54	11	in	in	ADP
bjos-8676163	54	12	chemical	chemical	NOUN
bjos-8676163	54	13	defined	define	VERB
bjos-8676163	54	14	medium	medium	NOUN
bjos-8676163	54	15	4	4	NUM
bjos-8676163	54	16	queiroz	queiroz	ADV
bjos-8676163	54	17	et	et	PROPN
bjos-8676163	55	1	al	al	PROPN
bjos-8676163	55	2	.	.	PROPN
bjos-8676163	55	3	braz	braz	PROPN
bjos-8676163	55	4	j	j	PROPN
bjos-8676163	55	5	oral	oral	PROPN
bjos-8676163	55	6	sci	sci	PROPN
bjos-8676163	55	7	.	.	PUNCT
bjos-8676163	56	1	2024;23	2024;23	NUM
bjos-8676163	56	2	:	:	PUNCT
bjos-8676163	56	3	e246163	e246163	NOUN
bjos-8676163	56	4	(	(	PUNCT
bjos-8676163	56	5	cdm	cdm	NOUN
bjos-8676163	56	6	)	)	PUNCT
bjos-8676163	56	7	containing	contain	VERB
bjos-8676163	56	8	1	1	NUM
bjos-8676163	56	9	%	%	NOUN
bjos-8676163	56	10	glucose15	glucose15	NOUN
bjos-8676163	56	11	.	.	PUNCT
bjos-8676163	57	1	overnight	overnight	ADJ
bjos-8676163	57	2	culture	culture	NOUN
bjos-8676163	57	3	of	of	ADP
bjos-8676163	57	4	s.	s.	PROPN
bjos-8676163	57	5	mutans	mutans	PROPN
bjos-8676163	57	6	sm120	sm120	ADJ
bjos-8676163	57	7	reporter	reporter	NOUN
bjos-8676163	57	8	strain	strain	NOUN
bjos-8676163	57	9	was	be	AUX
bjos-8676163	57	10	adjusted	adjust	VERB
bjos-8676163	57	11	to	to	ADP
bjos-8676163	57	12	an	an	DET
bjos-8676163	57	13	od	od	NUM
bjos-8676163	57	14	0.7	0.7	NUM
bjos-8676163	57	15	(	(	PUNCT
bjos-8676163	57	16	600	600	NUM
bjos-8676163	57	17	nm	nm	NOUN
bjos-8676163	57	18	)	)	PUNCT
bjos-8676163	57	19	.	.	PUNCT
bjos-8676163	58	1	the	the	DET
bjos-8676163	58	2	enzymes	enzyme	NOUN
bjos-8676163	58	3	,	,	PUNCT
bjos-8676163	58	4	active	active	ADJ
bjos-8676163	58	5	or	or	CCONJ
bjos-8676163	58	6	denatured	denature	VERB
bjos-8676163	58	7	,	,	PUNCT
bjos-8676163	58	8	were	be	AUX
bjos-8676163	58	9	prepared	prepare	VERB
bjos-8676163	58	10	at	at	ADP
bjos-8676163	58	11	a	a	DET
bjos-8676163	58	12	concentration	concentration	NOUN
bjos-8676163	58	13	of	of	ADP
bjos-8676163	58	14	0.125	0.125	NUM
bjos-8676163	58	15	mg	mg	NOUN
bjos-8676163	58	16	/	/	SYM
bjos-8676163	58	17	ml	ml	NOUN
bjos-8676163	58	18	(	(	PUNCT
bjos-8676163	58	19	w	w	NOUN
bjos-8676163	58	20	/	/	SYM
bjos-8676163	58	21	v	v	NOUN
bjos-8676163	58	22	)	)	PUNCT
bjos-8676163	58	23	in	in	ADP
bjos-8676163	58	24	the	the	DET
bjos-8676163	58	25	bacterial	bacterial	ADJ
bjos-8676163	58	26	inoculum	inoculum	NOUN
bjos-8676163	58	27	.	.	PUNCT
bjos-8676163	59	1	this	this	DET
bjos-8676163	59	2	enzyme	enzyme	NOUN
bjos-8676163	59	3	concentration	concentration	NOUN
bjos-8676163	59	4	was	be	AUX
bjos-8676163	59	5	chosen	choose	VERB
bjos-8676163	59	6	based	base	VERB
bjos-8676163	59	7	on	on	ADP
bjos-8676163	59	8	our	our	PRON
bjos-8676163	59	9	previous	previous	ADJ
bjos-8676163	59	10	study3	study3	NOUN
bjos-8676163	59	11	,	,	PUNCT
bjos-8676163	59	12	where	where	SCONJ
bjos-8676163	59	13	the	the	DET
bjos-8676163	59	14	lower	low	ADJ
bjos-8676163	59	15	dosage	dosage	NOUN
bjos-8676163	59	16	to	to	PART
bjos-8676163	59	17	cause	cause	VERB
bjos-8676163	59	18	a	a	DET
bjos-8676163	59	19	significant	significant	ADJ
bjos-8676163	59	20	s.	s.	PROPN
bjos-8676163	59	21	mutans	mutans	PROPN
bjos-8676163	59	22	biofilm	biofilm	NOUN
bjos-8676163	59	23	degradation	degradation	NOUN
bjos-8676163	59	24	was	be	AUX
bjos-8676163	59	25	0.125	0.125	NUM
bjos-8676163	59	26	mg	mg	NOUN
bjos-8676163	59	27	/	/	SYM
bjos-8676163	59	28	ml	ml	NOUN
bjos-8676163	59	29	(	(	PUNCT
bjos-8676163	59	30	w	w	NOUN
bjos-8676163	59	31	/	/	SYM
bjos-8676163	59	32	v	v	NOUN
bjos-8676163	59	33	)	)	PUNCT
bjos-8676163	59	34	.	.	PUNCT
bjos-8676163	60	1	the	the	DET
bjos-8676163	60	2	positive	positive	ADJ
bjos-8676163	60	3	control	control	NOUN
bjos-8676163	60	4	was	be	AUX
bjos-8676163	60	5	prepared	prepare	VERB
bjos-8676163	60	6	with	with	ADP
bjos-8676163	60	7	0.12	0.12	NUM
bjos-8676163	60	8	%	%	NOUN
bjos-8676163	60	9	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	60	10	digluconate	digluconate	NOUN
bjos-8676163	60	11	in	in	ADP
bjos-8676163	60	12	bacterial	bacterial	ADJ
bjos-8676163	60	13	inoculum	inoculum	NOUN
bjos-8676163	60	14	,	,	PUNCT
bjos-8676163	60	15	as	as	ADV
bjos-8676163	60	16	well	well	ADV
bjos-8676163	60	17	as	as	ADP
bjos-8676163	60	18	a	a	DET
bjos-8676163	60	19	group	group	NOUN
bjos-8676163	60	20	with	with	ADP
bjos-8676163	60	21	0.12	0.12	NUM
bjos-8676163	60	22	%	%	NOUN
bjos-8676163	60	23	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	60	24	digluconate	digluconate	NOUN
bjos-8676163	60	25	in	in	ADP
bjos-8676163	60	26	pure	pure	ADJ
bjos-8676163	60	27	medium	medium	NOUN
bjos-8676163	60	28	.	.	PUNCT
bjos-8676163	61	1	a	a	DET
bjos-8676163	61	2	negative	negative	ADJ
bjos-8676163	61	3	control	control	NOUN
bjos-8676163	61	4	group	group	NOUN
bjos-8676163	61	5	consisting	consist	VERB
bjos-8676163	61	6	of	of	ADP
bjos-8676163	61	7	the	the	DET
bjos-8676163	61	8	inoculum	inoculum	NOUN
bjos-8676163	61	9	without	without	ADP
bjos-8676163	61	10	any	any	DET
bjos-8676163	61	11	treatment	treatment	NOUN
bjos-8676163	61	12	and	and	CCONJ
bjos-8676163	61	13	a	a	DET
bjos-8676163	61	14	blank	blank	NOUN
bjos-8676163	61	15	containing	contain	VERB
bjos-8676163	61	16	only	only	ADV
bjos-8676163	61	17	pure	pure	ADJ
bjos-8676163	61	18	medium	medium	NOUN
bjos-8676163	61	19	were	be	AUX
bjos-8676163	61	20	also	also	ADV
bjos-8676163	61	21	prepared	prepare	VERB
bjos-8676163	61	22	.	.	PUNCT
bjos-8676163	62	1	a	a	DET
bjos-8676163	62	2	group	group	NOUN
bjos-8676163	62	3	containing	contain	VERB
bjos-8676163	62	4	inoculum	inoculum	NOUN
bjos-8676163	62	5	without	without	ADP
bjos-8676163	62	6	added	add	VERB
bjos-8676163	62	7	luciferin	luciferin	NOUN
bjos-8676163	62	8	was	be	AUX
bjos-8676163	62	9	also	also	ADV
bjos-8676163	62	10	included	include	VERB
bjos-8676163	62	11	as	as	ADP
bjos-8676163	62	12	a	a	DET
bjos-8676163	62	13	control	control	NOUN
bjos-8676163	62	14	in	in	ADP
bjos-8676163	62	15	the	the	DET
bjos-8676163	62	16	luminescence	luminescence	NOUN
bjos-8676163	62	17	assay	assay	VERB
bjos-8676163	62	18	.	.	PUNCT
bjos-8676163	63	1	aliquots	aliquot	NOUN
bjos-8676163	63	2	of	of	ADP
bjos-8676163	63	3	200	200	NUM
bjos-8676163	63	4	µl	µl	NOUN
bjos-8676163	63	5	of	of	ADP
bjos-8676163	63	6	the	the	DET
bjos-8676163	63	7	mixtures	mixture	NOUN
bjos-8676163	63	8	were	be	AUX
bjos-8676163	63	9	added	add	VERB
bjos-8676163	63	10	in	in	ADP
bjos-8676163	63	11	96	96	NUM
bjos-8676163	63	12	-	-	PUNCT
bjos-8676163	63	13	well	well	ADV
bjos-8676163	63	14	flat	flat	ADJ
bjos-8676163	63	15	bottom	bottom	ADJ
bjos-8676163	63	16	plates	plate	NOUN
bjos-8676163	63	17	(	(	PUNCT
bjos-8676163	63	18	nunc	nunc	NOUN
bjos-8676163	63	19	thermo	thermo	NOUN
bjos-8676163	63	20	scientific	scientific	NOUN
bjos-8676163	63	21	)	)	PUNCT
bjos-8676163	63	22	,	,	PUNCT
bjos-8676163	63	23	followed	follow	VERB
bjos-8676163	63	24	by	by	ADP
bjos-8676163	63	25	the	the	DET
bjos-8676163	63	26	addition	addition	NOUN
bjos-8676163	63	27	in	in	ADP
bjos-8676163	63	28	each	each	DET
bjos-8676163	63	29	well	well	NOUN
bjos-8676163	63	30	of	of	ADP
bjos-8676163	63	31	10	10	NUM
bjos-8676163	63	32	μl	μl	ADP
bjos-8676163	63	33	of	of	ADP
bjos-8676163	63	34	1.0	1.0	NUM
bjos-8676163	63	35	mm	mm	NOUN
bjos-8676163	63	36	luciferin	luciferin	NOUN
bjos-8676163	63	37	solution	solution	NOUN
bjos-8676163	63	38	(	(	PUNCT
bjos-8676163	63	39	synchem	synchem	NOUN
bjos-8676163	63	40	,	,	PUNCT
bjos-8676163	63	41	felsberg	felsberg	PROPN
bjos-8676163	63	42	-	-	PUNCT
bjos-8676163	63	43	altenberg	altenberg	PROPN
bjos-8676163	63	44	,	,	PUNCT
bjos-8676163	63	45	germany	germany	PROPN
bjos-8676163	63	46	)	)	PUNCT
bjos-8676163	63	47	at	at	ADP
bjos-8676163	63	48	room	room	NOUN
bjos-8676163	63	49	temperature	temperature	NOUN
bjos-8676163	63	50	.	.	PUNCT
bjos-8676163	64	1	the	the	DET
bjos-8676163	64	2	plates	plate	NOUN
bjos-8676163	64	3	were	be	AUX
bjos-8676163	64	4	incubated	incubate	VERB
bjos-8676163	64	5	at	at	ADP
bjos-8676163	64	6	37	37	NUM
bjos-8676163	64	7	°	°	NOUN
bjos-8676163	64	8	c	c	NOUN
bjos-8676163	64	9	,	,	PUNCT
bjos-8676163	64	10	10	10	NUM
bjos-8676163	64	11	%	%	NOUN
bjos-8676163	64	12	co2	co2	NOUN
bjos-8676163	64	13	for	for	ADP
bjos-8676163	64	14	10	10	NUM
bjos-8676163	64	15	h.	h.	NOUN
bjos-8676163	64	16	the	the	DET
bjos-8676163	64	17	optical	optical	ADJ
bjos-8676163	64	18	density	density	NOUN
bjos-8676163	64	19	(	(	PUNCT
bjos-8676163	64	20	od	od	NOUN
bjos-8676163	64	21	)	)	PUNCT
bjos-8676163	64	22	,	,	PUNCT
bjos-8676163	64	23	as	as	ADP
bjos-8676163	64	24	an	an	DET
bjos-8676163	64	25	indicative	indicative	ADJ
bjos-8676163	64	26	of	of	ADP
bjos-8676163	64	27	bacterial	bacterial	ADJ
bjos-8676163	64	28	growth	growth	NOUN
bjos-8676163	64	29	,	,	PUNCT
bjos-8676163	64	30	and	and	CCONJ
bjos-8676163	64	31	relative	relative	ADJ
bjos-8676163	64	32	light	light	ADJ
bjos-8676163	64	33	unit	unit	NOUN
bjos-8676163	64	34	(	(	PUNCT
bjos-8676163	64	35	rlu	rlu	PROPN
bjos-8676163	64	36	)	)	PUNCT
bjos-8676163	64	37	,	,	PUNCT
bjos-8676163	64	38	as	as	ADP
bjos-8676163	64	39	an	an	DET
bjos-8676163	64	40	indicative	indicative	ADJ
bjos-8676163	64	41	of	of	ADP
bjos-8676163	64	42	bacterial	bacterial	ADJ
bjos-8676163	64	43	metabolism	metabolism	NOUN
bjos-8676163	64	44	,	,	PUNCT
bjos-8676163	64	45	were	be	AUX
bjos-8676163	64	46	measured	measure	VERB
bjos-8676163	64	47	every	every	DET
bjos-8676163	64	48	30	30	NUM
bjos-8676163	64	49	min	min	NOUN
bjos-8676163	64	50	after	after	ADP
bjos-8676163	64	51	a	a	DET
bjos-8676163	64	52	10	10	NUM
bjos-8676163	64	53	-	-	PUNCT
bjos-8676163	64	54	seconds	second	NOUN
bjos-8676163	64	55	elliptical	elliptical	ADJ
bjos-8676163	64	56	agitation	agitation	NOUN
bjos-8676163	64	57	in	in	ADP
bjos-8676163	64	58	a	a	DET
bjos-8676163	64	59	microplate	microplate	NOUN
bjos-8676163	64	60	reader	reader	NOUN
bjos-8676163	64	61	(	(	PUNCT
bjos-8676163	64	62	synergy	synergy	NOUN
bjos-8676163	64	63	ht	ht	PROPN
bjos-8676163	64	64	;	;	PUNCT
bjos-8676163	64	65	biotek	biotek	PROPN
bjos-8676163	64	66	,	,	PUNCT
bjos-8676163	64	67	winooski	winooski	NOUN
bjos-8676163	64	68	,	,	PUNCT
bjos-8676163	64	69	vt	vt	PROPN
bjos-8676163	64	70	,	,	PUNCT
bjos-8676163	64	71	usa	usa	PROPN
bjos-8676163	64	72	)	)	PUNCT
bjos-8676163	64	73	.	.	PUNCT
bjos-8676163	65	1	the	the	DET
bjos-8676163	65	2	data	datum	NOUN
bjos-8676163	65	3	of	of	ADP
bjos-8676163	65	4	chx	chx	PROPN
bjos-8676163	65	5	in	in	ADP
bjos-8676163	65	6	inoculum	inoculum	NOUN
bjos-8676163	65	7	was	be	AUX
bjos-8676163	65	8	subtracted	subtract	VERB
bjos-8676163	65	9	from	from	ADP
bjos-8676163	65	10	that	that	PRON
bjos-8676163	65	11	in	in	ADP
bjos-8676163	65	12	the	the	DET
bjos-8676163	65	13	pure	pure	ADJ
bjos-8676163	65	14	medium	medium	NOUN
bjos-8676163	65	15	,	,	PUNCT
bjos-8676163	65	16	as	as	SCONJ
bjos-8676163	65	17	the	the	DET
bjos-8676163	65	18	antimicrobial	antimicrobial	NOUN
bjos-8676163	65	19	produced	produce	VERB
bjos-8676163	65	20	a	a	DET
bjos-8676163	65	21	whitish	whitish	ADJ
bjos-8676163	65	22	color	color	NOUN
bjos-8676163	65	23	in	in	ADP
bjos-8676163	65	24	the	the	DET
bjos-8676163	65	25	medium	medium	NOUN
bjos-8676163	65	26	,	,	PUNCT
bjos-8676163	65	27	which	which	PRON
bjos-8676163	65	28	affected	affect	VERB
bjos-8676163	65	29	od	od	PROPN
bjos-8676163	65	30	measurement	measurement	NOUN
bjos-8676163	65	31	.	.	PUNCT
bjos-8676163	66	1	rlu	rlu	PROPN
bjos-8676163	66	2	and	and	CCONJ
bjos-8676163	66	3	od	od	PROPN
bjos-8676163	66	4	data	datum	NOUN
bjos-8676163	66	5	were	be	AUX
bjos-8676163	66	6	log	log	NOUN
bjos-8676163	66	7	transformed	transform	VERB
bjos-8676163	66	8	and	and	CCONJ
bjos-8676163	66	9	the	the	DET
bjos-8676163	66	10	area	area	NOUN
bjos-8676163	66	11	under	under	ADP
bjos-8676163	66	12	the	the	DET
bjos-8676163	66	13	curve	curve	NOUN
bjos-8676163	66	14	(	(	PUNCT
bjos-8676163	66	15	auc	auc	NOUN
bjos-8676163	66	16	)	)	PUNCT
bjos-8676163	66	17	for	for	ADP
bjos-8676163	66	18	od	od	ADV
bjos-8676163	66	19	or	or	CCONJ
bjos-8676163	66	20	rlu	rlu	ADJ
bjos-8676163	66	21	x	x	NOUN
bjos-8676163	66	22	h	h	NOUN
bjos-8676163	66	23	were	be	AUX
bjos-8676163	66	24	calculated	calculate	VERB
bjos-8676163	66	25	.	.	PUNCT
bjos-8676163	67	1	three	three	NUM
bjos-8676163	67	2	independent	independent	ADJ
bjos-8676163	67	3	experiments	experiment	NOUN
bjos-8676163	67	4	were	be	AUX
bjos-8676163	67	5	conducted	conduct	VERB
bjos-8676163	67	6	in	in	ADP
bjos-8676163	67	7	triplicate	triplicate	NOUN
bjos-8676163	67	8	,	,	PUNCT
bjos-8676163	67	9	with	with	SCONJ
bjos-8676163	67	10	each	each	DET
bjos-8676163	67	11	experiment	experiment	NOUN
bjos-8676163	67	12	carried	carry	VERB
bjos-8676163	67	13	out	out	ADP
bjos-8676163	67	14	on	on	ADP
bjos-8676163	67	15	different	different	ADJ
bjos-8676163	67	16	days	day	NOUN
bjos-8676163	67	17	.	.	PUNCT
bjos-8676163	68	1	statistical	statistical	ADJ
bjos-8676163	68	2	analyses	analysis	NOUN
bjos-8676163	68	3	the	the	DET
bjos-8676163	68	4	data	datum	NOUN
bjos-8676163	68	5	were	be	AUX
bjos-8676163	68	6	analyzed	analyze	VERB
bjos-8676163	68	7	by	by	ADP
bjos-8676163	68	8	comparing	compare	VERB
bjos-8676163	68	9	treatment	treatment	NOUN
bjos-8676163	68	10	groups	group	NOUN
bjos-8676163	68	11	to	to	ADP
bjos-8676163	68	12	the	the	DET
bjos-8676163	68	13	positive	positive	ADJ
bjos-8676163	68	14	control	control	NOUN
bjos-8676163	68	15	group	group	NOUN
bjos-8676163	68	16	(	(	PUNCT
bjos-8676163	68	17	cdm	cdm	PROPN
bjos-8676163	68	18	+	+	PROPN
bjos-8676163	68	19	s.	s.	PROPN
bjos-8676163	68	20	mutans	mutans	PROPN
bjos-8676163	68	21	for	for	ADP
bjos-8676163	68	22	od	od	PROPN
bjos-8676163	68	23	data	datum	NOUN
bjos-8676163	68	24	,	,	PUNCT
bjos-8676163	68	25	or	or	CCONJ
bjos-8676163	68	26	cdm	cdm	PROPN
bjos-8676163	68	27	+	+	CCONJ
bjos-8676163	68	28	s.	s.	PROPN
bjos-8676163	68	29	mutans	mutans	PROPN
bjos-8676163	68	30	+	+	CCONJ
bjos-8676163	68	31	luciferin	luciferin	NOUN
bjos-8676163	68	32	for	for	ADP
bjos-8676163	68	33	rlu	rlu	PROPN
bjos-8676163	68	34	data	datum	NOUN
bjos-8676163	68	35	)	)	PUNCT
bjos-8676163	68	36	.	.	PUNCT
bjos-8676163	69	1	each	each	DET
bjos-8676163	69	2	time	time	NOUN
bjos-8676163	69	3	point	point	NOUN
bjos-8676163	69	4	for	for	ADP
bjos-8676163	69	5	od	od	NOUN
bjos-8676163	69	6	and	and	CCONJ
bjos-8676163	69	7	rlu	rlu	PROPN
bjos-8676163	69	8	curves	curve	NOUN
bjos-8676163	69	9	was	be	AUX
bjos-8676163	69	10	analyzed	analyze	VERB
bjos-8676163	69	11	by	by	ADP
bjos-8676163	69	12	two	two	NUM
bjos-8676163	69	13	-	-	PUNCT
bjos-8676163	69	14	way	way	NOUN
bjos-8676163	69	15	anova	anova	PROPN
bjos-8676163	69	16	followed	follow	VERB
bjos-8676163	69	17	by	by	ADP
bjos-8676163	69	18	dunnett	dunnett	PROPN
bjos-8676163	69	19	’s	’s	PART
bjos-8676163	69	20	test	test	NOUN
bjos-8676163	69	21	(	(	PUNCT
bjos-8676163	69	22	α=5	α=5	NOUN
bjos-8676163	69	23	%	%	NOUN
bjos-8676163	69	24	)	)	PUNCT
bjos-8676163	69	25	,	,	PUNCT
bjos-8676163	69	26	considering	consider	VERB
bjos-8676163	69	27	as	as	ADP
bjos-8676163	69	28	factors	factor	NOUN
bjos-8676163	69	29	treatments	treatment	NOUN
bjos-8676163	69	30	and	and	CCONJ
bjos-8676163	69	31	time	time	NOUN
bjos-8676163	69	32	.	.	PUNCT
bjos-8676163	70	1	the	the	DET
bjos-8676163	70	2	auc	auc	NOUN
bjos-8676163	70	3	(	(	PUNCT
bjos-8676163	70	4	od	od	NOUN
bjos-8676163	70	5	or	or	CCONJ
bjos-8676163	70	6	rlu	rlu	ADJ
bjos-8676163	70	7	x	x	ADJ
bjos-8676163	70	8	h	h	NOUN
bjos-8676163	70	9	)	)	PUNCT
bjos-8676163	70	10	was	be	AUX
bjos-8676163	70	11	analyzed	analyze	VERB
bjos-8676163	70	12	by	by	ADP
bjos-8676163	70	13	one	one	NUM
bjos-8676163	70	14	-	-	PUNCT
bjos-8676163	70	15	way	way	NOUN
bjos-8676163	70	16	anova	anova	PROPN
bjos-8676163	70	17	,	,	PUNCT
bjos-8676163	70	18	dunnett	dunnett	PROPN
bjos-8676163	70	19	’s	’s	PART
bjos-8676163	70	20	test	test	NOUN
bjos-8676163	70	21	(	(	PUNCT
bjos-8676163	70	22	α=5	α=5	NOUN
bjos-8676163	70	23	%	%	NOUN
bjos-8676163	70	24	)	)	PUNCT
bjos-8676163	70	25	.	.	PUNCT
bjos-8676163	71	1	statistical	statistical	ADJ
bjos-8676163	71	2	analysis	analysis	NOUN
bjos-8676163	71	3	was	be	AUX
bjos-8676163	71	4	conducted	conduct	VERB
bjos-8676163	71	5	using	use	VERB
bjos-8676163	71	6	graphpad	graphpad	NOUN
bjos-8676163	71	7	prism	prism	NOUN
bjos-8676163	71	8	9	9	NUM
bjos-8676163	71	9	,	,	PUNCT
bjos-8676163	71	10	and	and	CCONJ
bjos-8676163	71	11	a	a	DET
bjos-8676163	71	12	p	p	NOUN
bjos-8676163	71	13	-	-	PUNCT
bjos-8676163	71	14	value	value	NOUN
bjos-8676163	71	15	<	<	X
bjos-8676163	71	16	0.05	0.05	NUM
bjos-8676163	71	17	was	be	AUX
bjos-8676163	71	18	considered	consider	VERB
bjos-8676163	71	19	statistically	statistically	ADV
bjos-8676163	71	20	significant	significant	ADJ
bjos-8676163	71	21	.	.	PUNCT
bjos-8676163	72	1	results	result	VERB
bjos-8676163	72	2	quantification	quantification	NOUN
bjos-8676163	72	3	of	of	ADP
bjos-8676163	72	4	optical	optical	ADJ
bjos-8676163	72	5	density	density	NOUN
bjos-8676163	72	6	(	(	PUNCT
bjos-8676163	72	7	od	od	NOUN
bjos-8676163	72	8	)	)	PUNCT
bjos-8676163	72	9	and	and	CCONJ
bjos-8676163	72	10	luminescence	luminescence	NOUN
bjos-8676163	72	11	(	(	PUNCT
bjos-8676163	72	12	rlu	rlu	NOUN
bjos-8676163	72	13	)	)	PUNCT
bjos-8676163	72	14	over	over	ADP
bjos-8676163	72	15	the	the	DET
bjos-8676163	72	16	10	10	NUM
bjos-8676163	72	17	-	-	PUNCT
bjos-8676163	72	18	h	h	NOUN
bjos-8676163	72	19	incubation	incubation	NOUN
bjos-8676163	72	20	period	period	NOUN
bjos-8676163	72	21	revealed	reveal	VERB
bjos-8676163	72	22	that	that	SCONJ
bjos-8676163	72	23	the	the	DET
bjos-8676163	72	24	commercial	commercial	ADJ
bjos-8676163	72	25	dextranase	dextranase	NOUN
bjos-8676163	72	26	exhibited	exhibit	VERB
bjos-8676163	72	27	inhibitory	inhibitory	ADJ
bjos-8676163	72	28	effect	effect	NOUN
bjos-8676163	72	29	on	on	ADP
bjos-8676163	72	30	the	the	DET
bjos-8676163	72	31	growth	growth	NOUN
bjos-8676163	72	32	of	of	ADP
bjos-8676163	72	33	s.	s.	PROPN
bjos-8676163	72	34	mutans	mutans	PROPN
bjos-8676163	72	35	.	.	PUNCT
bjos-8676163	73	1	the	the	DET
bjos-8676163	73	2	commercial	commercial	ADJ
bjos-8676163	73	3	dextranase	dextranase	NOUN
bjos-8676163	73	4	,	,	PUNCT
bjos-8676163	73	5	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	73	6	and	and	CCONJ
bjos-8676163	73	7	negative	negative	ADJ
bjos-8676163	73	8	control	control	NOUN
bjos-8676163	73	9	groups	group	NOUN
bjos-8676163	73	10	presented	present	VERB
bjos-8676163	73	11	no	no	DET
bjos-8676163	73	12	growth	growth	NOUN
bjos-8676163	73	13	quantified	quantify	VERB
bjos-8676163	73	14	by	by	ADP
bjos-8676163	73	15	od	od	ADP
bjos-8676163	73	16	or	or	CCONJ
bjos-8676163	73	17	ldh	ldh	NOUN
bjos-8676163	73	18	activity	activity	NOUN
bjos-8676163	73	19	by	by	ADP
bjos-8676163	73	20	rlu	rlu	NOUN
bjos-8676163	73	21	when	when	SCONJ
bjos-8676163	73	22	compared	compare	VERB
bjos-8676163	73	23	to	to	ADP
bjos-8676163	73	24	the	the	DET
bjos-8676163	73	25	respective	respective	ADJ
bjos-8676163	73	26	positive	positive	ADJ
bjos-8676163	73	27	control	control	NOUN
bjos-8676163	73	28	groups	group	NOUN
bjos-8676163	73	29	after	after	ADP
bjos-8676163	73	30	5	5	NUM
bjos-8676163	73	31	h	h	NOUN
bjos-8676163	73	32	-	-	PUNCT
bjos-8676163	73	33	growth	growth	NOUN
bjos-8676163	73	34	(	(	PUNCT
bjos-8676163	73	35	fig	fig	NOUN
bjos-8676163	73	36	1.a	1.a	NUM
bjos-8676163	73	37	)	)	PUNCT
bjos-8676163	73	38	and	and	CCONJ
bjos-8676163	73	39	1	1	NUM
bjos-8676163	73	40	h	h	NOUN
bjos-8676163	73	41	-	-	PUNCT
bjos-8676163	73	42	growth	growth	NOUN
bjos-8676163	73	43	(	(	PUNCT
bjos-8676163	73	44	fig	fig	NOUN
bjos-8676163	73	45	2.a	2.a	NUM
bjos-8676163	73	46	)	)	PUNCT
bjos-8676163	73	47	,	,	PUNCT
bjos-8676163	73	48	respectively	respectively	ADV
bjos-8676163	73	49	.	.	PUNCT
bjos-8676163	74	1	however	however	ADV
bjos-8676163	74	2	,	,	PUNCT
bjos-8676163	74	3	this	this	DET
bjos-8676163	74	4	effect	effect	NOUN
bjos-8676163	74	5	was	be	AUX
bjos-8676163	74	6	not	not	PART
bjos-8676163	74	7	observed	observe	VERB
bjos-8676163	74	8	for	for	ADP
bjos-8676163	74	9	the	the	DET
bjos-8676163	74	10	commercial	commercial	ADJ
bjos-8676163	74	11	dextranase	dextranase	NOUN
bjos-8676163	74	12	submitted	submit	VERB
bjos-8676163	74	13	to	to	ADP
bjos-8676163	74	14	the	the	DET
bjos-8676163	74	15	heat	heat	NOUN
bjos-8676163	74	16	-	-	PUNCT
bjos-8676163	74	17	denaturation	denaturation	NOUN
bjos-8676163	74	18	procedure	procedure	NOUN
bjos-8676163	74	19	(	(	PUNCT
bjos-8676163	74	20	fig	fig	NOUN
bjos-8676163	74	21	1.a	1.a	NUM
bjos-8676163	74	22	and	and	CCONJ
bjos-8676163	74	23	2.a	2.a	NUM
bjos-8676163	74	24	)	)	PUNCT
bjos-8676163	74	25	.	.	PUNCT
bjos-8676163	75	1	additionally	additionally	ADV
bjos-8676163	75	2	,	,	PUNCT
bjos-8676163	75	3	cultures	culture	NOUN
bjos-8676163	75	4	in	in	ADP
bjos-8676163	75	5	the	the	DET
bjos-8676163	75	6	presence	presence	NOUN
bjos-8676163	75	7	of	of	ADP
bjos-8676163	75	8	the	the	DET
bjos-8676163	75	9	other	other	ADJ
bjos-8676163	75	10	enzymes	enzyme	NOUN
bjos-8676163	75	11	(	(	PUNCT
bjos-8676163	75	12	whether	whether	SCONJ
bjos-8676163	75	13	denatured	denature	VERB
bjos-8676163	75	14	or	or	CCONJ
bjos-8676163	75	15	not	not	PART
bjos-8676163	75	16	)	)	PUNCT
bjos-8676163	75	17	exhibited	exhibit	VERB
bjos-8676163	75	18	similar	similar	ADJ
bjos-8676163	75	19	growth	growth	NOUN
bjos-8676163	75	20	and	and	CCONJ
bjos-8676163	75	21	metabolic	metabolic	NOUN
bjos-8676163	75	22	patterns	pattern	NOUN
bjos-8676163	75	23	to	to	ADP
bjos-8676163	75	24	their	their	PRON
bjos-8676163	75	25	respective	respective	ADJ
bjos-8676163	75	26	positive	positive	ADJ
bjos-8676163	75	27	control	control	NOUN
bjos-8676163	75	28	groups	group	NOUN
bjos-8676163	75	29	over	over	ADP
bjos-8676163	75	30	the	the	DET
bjos-8676163	75	31	incubation	incubation	NOUN
bjos-8676163	75	32	period	period	NOUN
bjos-8676163	75	33	(	(	PUNCT
bjos-8676163	75	34	fig	fig	NOUN
bjos-8676163	75	35	1.a	1.a	NUM
bjos-8676163	75	36	and	and	CCONJ
bjos-8676163	75	37	2.a	2.a	NUM
bjos-8676163	75	38	)	)	PUNCT
bjos-8676163	75	39	.	.	PUNCT
bjos-8676163	76	1	5	5	NUM
bjos-8676163	76	2	queiroz	queiroz	ADV
bjos-8676163	76	3	et	et	PROPN
bjos-8676163	76	4	al	al	PROPN
bjos-8676163	76	5	.	.	PROPN
bjos-8676163	76	6	braz	braz	PROPN
bjos-8676163	76	7	j	j	PROPN
bjos-8676163	76	8	oral	oral	PROPN
bjos-8676163	76	9	sci	sci	PROPN
bjos-8676163	76	10	.	.	PUNCT
bjos-8676163	77	1	2024;23	2024;23	NUM
bjos-8676163	77	2	:	:	PUNCT
bjos-8676163	77	3	e246163	e246163	NOUN
bjos-8676163	77	4	a	a	DET
bjos-8676163	77	5	0.5	0.5	NUM
bjos-8676163	77	6	0.0	0.0	NUM
bjos-8676163	77	7	-0.5	-0.5	NUM
bjos-8676163	77	8	-1.0	-1.0	PROPN
bjos-8676163	77	9	-1.5	-1.5	PUNCT
bjos-8676163	77	10	time	time	NOUN
bjos-8676163	77	11	(	(	PUNCT
bjos-8676163	77	12	h	h	NOUN
bjos-8676163	77	13	)	)	PUNCT
bjos-8676163	77	14	lo	lo	PROPN
bjos-8676163	77	15	g	g	PROPN
bjos-8676163	77	16	ab	ab	PROPN
bjos-8676163	77	17	so	so	ADV
bjos-8676163	77	18	rb	rb	PROPN
bjos-8676163	77	19	an	an	DET
bjos-8676163	77	20	ce	ce	NOUN
bjos-8676163	77	21	(	(	PUNCT
bjos-8676163	77	22	o	o	NOUN
bjos-8676163	77	23	d	d	X
bjos-8676163	77	24	60	60	NUM
bjos-8676163	77	25	0	0	NUM
bjos-8676163	77	26	nm	nm	NOUN
bjos-8676163	77	27	)	)	PUNCT
bjos-8676163	77	28	mutanase	mutanase	NOUN
bjos-8676163	77	29	mutanase	mutanase	NOUN
bjos-8676163	77	30	denatured	denature	VERB
bjos-8676163	77	31	dextranase	dextranase	NOUN
bjos-8676163	77	32	sig	sig	NOUN
bjos-8676163	77	33	:	:	PUNCT
bjos-8676163	77	34	cdm	cdm	PROPN
bjos-8676163	77	35	and	and	CCONJ
bjos-8676163	77	36	dextranase	dextranase	PROPN
bjos-8676163	77	37	sigma	sigma	PROPN
bjos-8676163	77	38	;	;	PUNCT
bjos-8676163	77	39	ns	ns	NUM
bjos-8676163	77	40	:	:	PUNCT
bjos-8676163	77	41	all	all	DET
bjos-8676163	77	42	other	other	ADJ
bjos-8676163	77	43	groups	group	NOUN
bjos-8676163	77	44	.	.	PUNCT
bjos-8676163	78	1	commercial	commercial	ADJ
bjos-8676163	78	2	dextranase	dextranase	PROPN
bjos-8676163	78	3	commercial	commercial	ADJ
bjos-8676163	78	4	dextranase	dextranase	NOUN
bjos-8676163	78	5	denatureddextranase	denatureddextranase	NOUN
bjos-8676163	78	6	denatured	denature	VERB
bjos-8676163	78	7	cdm	cdm	PROPN
bjos-8676163	78	8	cdm	cdm	PROPN
bjos-8676163	79	1	+	+	CCONJ
bjos-8676163	79	2	s.	s.	PROPN
bjos-8676163	79	3	mutans	mutans	PROPN
bjos-8676163	79	4	cdm	cdm	PROPN
bjos-8676163	79	5	+	+	CCONJ
bjos-8676163	79	6	s.	s.	PROPN
bjos-8676163	79	7	mutans	mutans	PROPN
bjos-8676163	79	8	cdm	cdm	PROPN
bjos-8676163	79	9	mutanase	mutanase	PROPN
bjos-8676163	79	10	mutanase	mutanase	PROPN
bjos-8676163	79	11	denatured	denature	VERB
bjos-8676163	79	12	dextranase	dextranase	NOUN
bjos-8676163	79	13	dextranase	dextranase	NOUN
bjos-8676163	79	14	denatured	denature	VERB
bjos-8676163	79	15	commercial	commercial	ADJ
bjos-8676163	79	16	dextranase	dextranase	NOUN
bjos-8676163	79	17	commercial	commercial	ADJ
bjos-8676163	79	18	dextranase	dextranase	NOUN
bjos-8676163	79	19	denatured	denature	VERB
bjos-8676163	79	20	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	79	21	0.12	0.12	NUM
bjos-8676163	79	22	%	%	NOUN
bjos-8676163	79	23	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	79	24	0.12	0.12	NUM
bjos-8676163	79	25	%	%	NOUN
bjos-8676163	79	26	b	b	NOUN
bjos-8676163	79	27	0	0	NUM
bjos-8676163	79	28	2	2	NUM
bjos-8676163	79	29	4	4	NUM
bjos-8676163	79	30	6	6	NUM
bjos-8676163	79	31	8	8	NUM
bjos-8676163	79	32	10	10	NUM
bjos-8676163	79	33	auc	auc	NOUN
bjos-8676163	79	34	log	log	NOUN
bjos-8676163	79	35	abs	ab	NOUN
bjos-8676163	79	36	(	(	PUNCT
bjos-8676163	79	37	600	600	NUM
bjos-8676163	79	38	nm)xh	nm)xh	NOUN
bjos-8676163	79	39	figure	figure	NOUN
bjos-8676163	79	40	1	1	NUM
bjos-8676163	79	41	.	.	PUNCT
bjos-8676163	79	42	optical	optical	ADJ
bjos-8676163	79	43	density	density	NOUN
bjos-8676163	79	44	(	(	PUNCT
bjos-8676163	79	45	od	od	NOUN
bjos-8676163	79	46	)	)	PUNCT
bjos-8676163	79	47	quantification	quantification	NOUN
bjos-8676163	79	48	(	(	PUNCT
bjos-8676163	79	49	log	log	NOUN
bjos-8676163	79	50	)	)	PUNCT
bjos-8676163	79	51	.	.	PUNCT
bjos-8676163	80	1	a.	a.	PROPN
bjos-8676163	80	2	s.	s.	PROPN
bjos-8676163	80	3	mutans	mutan	VERB
bjos-8676163	80	4	10	10	NUM
bjos-8676163	80	5	h	h	NOUN
bjos-8676163	80	6	-	-	PUNCT
bjos-8676163	80	7	growth	growth	NOUN
bjos-8676163	80	8	curve	curve	NOUN
bjos-8676163	80	9	(	(	PUNCT
bjos-8676163	80	10	n=3	n=3	NOUN
bjos-8676163	80	11	;	;	PUNCT
bjos-8676163	80	12	mean	mean	NOUN
bjos-8676163	80	13	±	±	NUM
bjos-8676163	80	14	sd	sd	NOUN
bjos-8676163	80	15	)	)	PUNCT
bjos-8676163	80	16	according	accord	VERB
bjos-8676163	80	17	to	to	ADP
bjos-8676163	80	18	the	the	DET
bjos-8676163	80	19	treatments	treatment	NOUN
bjos-8676163	80	20	.	.	PUNCT
bjos-8676163	81	1	b.	b.	PROPN
bjos-8676163	81	2	area	area	PROPN
bjos-8676163	81	3	under	under	ADP
bjos-8676163	81	4	the	the	DET
bjos-8676163	81	5	curve	curve	NOUN
bjos-8676163	81	6	for	for	ADP
bjos-8676163	81	7	od	od	PROPN
bjos-8676163	81	8	x	x	PROPN
bjos-8676163	81	9	h.	h.	PROPN
bjos-8676163	81	10	*	*	PUNCT
bjos-8676163	81	11	means	mean	VERB
bjos-8676163	81	12	significant	significant	ADJ
bjos-8676163	81	13	differences	difference	NOUN
bjos-8676163	81	14	against	against	ADP
bjos-8676163	81	15	cdm	cdm	PROPN
bjos-8676163	81	16	+	+	CCONJ
bjos-8676163	81	17	s.	s.	PROPN
bjos-8676163	81	18	mutans	mutans	PROPN
bjos-8676163	81	19	control	control	PROPN
bjos-8676163	81	20	group	group	NOUN
bjos-8676163	81	21	.	.	PUNCT
bjos-8676163	82	1	the	the	DET
bjos-8676163	82	2	auc	auc	NOUN
bjos-8676163	82	3	data	datum	NOUN
bjos-8676163	82	4	for	for	ADP
bjos-8676163	82	5	both	both	DET
bjos-8676163	82	6	od	od	NOUN
bjos-8676163	82	7	and	and	CCONJ
bjos-8676163	82	8	rlu	rlu	AUX
bjos-8676163	82	9	compile	compile	VERB
bjos-8676163	82	10	the	the	DET
bjos-8676163	82	11	results	result	NOUN
bjos-8676163	82	12	observed	observe	VERB
bjos-8676163	82	13	at	at	ADP
bjos-8676163	82	14	each	each	DET
bjos-8676163	82	15	time	time	NOUN
bjos-8676163	82	16	point	point	NOUN
bjos-8676163	82	17	throughout	throughout	ADP
bjos-8676163	82	18	the	the	DET
bjos-8676163	82	19	entire	entire	ADJ
bjos-8676163	82	20	period	period	NOUN
bjos-8676163	82	21	of	of	ADP
bjos-8676163	82	22	the	the	DET
bjos-8676163	82	23	experiment	experiment	NOUN
bjos-8676163	82	24	.	.	PUNCT
bjos-8676163	83	1	the	the	DET
bjos-8676163	83	2	active	active	ADJ
bjos-8676163	83	3	commercial	commercial	ADJ
bjos-8676163	83	4	dextranase	dextranase	NOUN
bjos-8676163	83	5	exhibited	exhibit	VERB
bjos-8676163	83	6	lower	low	ADJ
bjos-8676163	83	7	values	value	NOUN
bjos-8676163	83	8	for	for	ADP
bjos-8676163	83	9	both	both	DET
bjos-8676163	83	10	growth	growth	NOUN
bjos-8676163	83	11	(	(	PUNCT
bjos-8676163	83	12	auc	auc	NOUN
bjos-8676163	83	13	-	-	PUNCT
bjos-8676163	83	14	od	od	NOUN
bjos-8676163	83	15	;	;	PUNCT
bjos-8676163	83	16	p<0.05	p<0.05	NOUN
bjos-8676163	83	17	;	;	PUNCT
bjos-8676163	83	18	fig	fig	NOUN
bjos-8676163	83	19	.	.	PUNCT
bjos-8676163	84	1	1b	1b	NUM
bjos-8676163	84	2	)	)	PUNCT
bjos-8676163	84	3	and	and	CCONJ
bjos-8676163	84	4	metabolism	metabolism	NOUN
bjos-8676163	84	5	(	(	PUNCT
bjos-8676163	84	6	auc	auc	NOUN
bjos-8676163	84	7	-	-	PUNCT
bjos-8676163	84	8	rlu	rlu	NOUN
bjos-8676163	84	9	;	;	PUNCT
bjos-8676163	84	10	p<0.05	p<0.05	NOUN
bjos-8676163	84	11	;	;	PUNCT
bjos-8676163	84	12	fig	fig	NOUN
bjos-8676163	84	13	.	.	PUNCT
bjos-8676163	84	14	2b	2b	NOUN
bjos-8676163	84	15	)	)	PUNCT
bjos-8676163	84	16	of	of	ADP
bjos-8676163	84	17	s.	s.	PROPN
bjos-8676163	84	18	mutans	mutans	PROPN
bjos-8676163	84	19	compared	compare	VERB
bjos-8676163	84	20	to	to	ADP
bjos-8676163	84	21	the	the	DET
bjos-8676163	84	22	positive	positive	ADJ
bjos-8676163	84	23	control	control	NOUN
bjos-8676163	84	24	.	.	PUNCT
bjos-8676163	85	1	however	however	ADV
bjos-8676163	85	2	,	,	PUNCT
bjos-8676163	85	3	the	the	DET
bjos-8676163	85	4	commercial	commercial	ADJ
bjos-8676163	85	5	heat	heat	NOUN
bjos-8676163	85	6	-	-	PUNCT
bjos-8676163	85	7	denatured	denature	VERB
bjos-8676163	85	8	dextranase	dextranase	NOUN
bjos-8676163	85	9	did	do	AUX
bjos-8676163	85	10	not	not	PART
bjos-8676163	85	11	differ	differ	VERB
bjos-8676163	85	12	significantly	significantly	ADV
bjos-8676163	85	13	from	from	ADP
bjos-8676163	85	14	the	the	DET
bjos-8676163	85	15	positive	positive	ADJ
bjos-8676163	85	16	control	control	NOUN
bjos-8676163	85	17	for	for	ADP
bjos-8676163	85	18	both	both	DET
bjos-8676163	85	19	analyses	analysis	NOUN
bjos-8676163	85	20	(	(	PUNCT
bjos-8676163	85	21	p	p	X
bjos-8676163	85	22	>	>	X
bjos-8676163	85	23	0.05	0.05	NUM
bjos-8676163	85	24	;	;	PUNCT
bjos-8676163	85	25	fig	fig	NOUN
bjos-8676163	85	26	.	.	PUNCT
bjos-8676163	86	1	1.b	1.b	NUM
bjos-8676163	86	2	and	and	CCONJ
bjos-8676163	86	3	2.b	2.b	NUM
bjos-8676163	86	4	)	)	PUNCT
bjos-8676163	86	5	.	.	PUNCT
bjos-8676163	87	1	mutanase	mutanase	NOUN
bjos-8676163	87	2	and	and	CCONJ
bjos-8676163	87	3	dextranase	dextranase	NOUN
bjos-8676163	87	4	,	,	PUNCT
bjos-8676163	87	5	whether	whether	SCONJ
bjos-8676163	87	6	denatured	denature	VERB
bjos-8676163	87	7	or	or	CCONJ
bjos-8676163	87	8	not	not	PART
bjos-8676163	87	9	,	,	PUNCT
bjos-8676163	87	10	showed	show	VERB
bjos-8676163	87	11	higher	high	ADJ
bjos-8676163	87	12	auc	auc	NOUN
bjos-8676163	87	13	values	value	NOUN
bjos-8676163	87	14	for	for	ADP
bjos-8676163	87	15	od	od	PROPN
bjos-8676163	87	16	(	(	PUNCT
bjos-8676163	87	17	p<0.05	p<0.05	PROPN
bjos-8676163	87	18	)	)	PUNCT
bjos-8676163	87	19	and	and	CCONJ
bjos-8676163	87	20	rlu	rlu	PROPN
bjos-8676163	87	21	(	(	PUNCT
bjos-8676163	87	22	p<0.05	p<0.05	PROPN
bjos-8676163	87	23	)	)	PUNCT
bjos-8676163	87	24	compared	compare	VERB
bjos-8676163	87	25	to	to	ADP
bjos-8676163	87	26	the	the	DET
bjos-8676163	87	27	positive	positive	ADJ
bjos-8676163	87	28	control	control	NOUN
bjos-8676163	87	29	.	.	PUNCT
bjos-8676163	88	1	6	6	NUM
bjos-8676163	88	2	queiroz	queiroz	ADV
bjos-8676163	88	3	et	et	PROPN
bjos-8676163	88	4	al	al	PROPN
bjos-8676163	88	5	.	.	PROPN
bjos-8676163	88	6	braz	braz	PROPN
bjos-8676163	88	7	j	j	PROPN
bjos-8676163	88	8	oral	oral	PROPN
bjos-8676163	88	9	sci	sci	PROPN
bjos-8676163	88	10	.	.	PUNCT
bjos-8676163	89	1	2024;23	2024;23	NUM
bjos-8676163	89	2	:	:	PUNCT
bjos-8676163	89	3	e246163	e246163	NOUN
bjos-8676163	89	4	a	a	DET
bjos-8676163	89	5	5	5	NUM
bjos-8676163	89	6	4	4	NUM
bjos-8676163	89	7	3	3	NUM
bjos-8676163	89	8	2	2	NUM
bjos-8676163	89	9	1	1	NUM
bjos-8676163	89	10	0	0	NUM
bjos-8676163	89	11	time	time	NOUN
bjos-8676163	89	12	(	(	PUNCT
bjos-8676163	89	13	h	h	NOUN
bjos-8676163	89	14	)	)	PUNCT
bjos-8676163	90	1	lo	lo	PROPN
bjos-8676163	90	2	g	g	PROPN
bjos-8676163	90	3	rl	rl	PROPN
bjos-8676163	90	4	u	u	PROPN
bjos-8676163	90	5	(	(	PUNCT
bjos-8676163	90	6	r	r	NOUN
bjos-8676163	90	7	el	el	PROPN
bjos-8676163	90	8	at	at	ADP
bjos-8676163	90	9	iv	iv	NUM
bjos-8676163	90	10	e	e	PROPN
bjos-8676163	90	11	li	li	PROPN
bjos-8676163	90	12	gh	gh	PROPN
bjos-8676163	90	13	t	t	PROPN
bjos-8676163	90	14	u	u	PROPN
bjos-8676163	90	15	ni	ni	PROPN
bjos-8676163	90	16	t	t	PROPN
bjos-8676163	90	17	)	)	PUNCT
bjos-8676163	90	18	mutanase	mutanase	NOUN
bjos-8676163	90	19	mutanase	mutanase	NOUN
bjos-8676163	90	20	denatured	denature	VERB
bjos-8676163	90	21	dextranase	dextranase	PROPN
bjos-8676163	90	22	sig	sig	NOUN
bjos-8676163	90	23	:	:	PUNCT
bjos-8676163	90	24	cdm	cdm	PROPN
bjos-8676163	90	25	,	,	PUNCT
bjos-8676163	90	26	cdm	cdm	PROPN
bjos-8676163	90	27	+	+	CCONJ
bjos-8676163	90	28	s.	s.	PROPN
bjos-8676163	90	29	mutans	mutans	PROPN
bjos-8676163	90	30	,	,	PUNCT
bjos-8676163	90	31	commercial	commercial	ADJ
bjos-8676163	90	32	dextranase	dextranase	NOUN
bjos-8676163	90	33	and	and	CCONJ
bjos-8676163	90	34	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	90	35	0.12	0.12	NUM
bjos-8676163	90	36	%	%	NOUN
bjos-8676163	90	37	;	;	PUNCT
bjos-8676163	90	38	ns	ns	NUM
bjos-8676163	90	39	:	:	PUNCT
bjos-8676163	90	40	other	other	ADJ
bjos-8676163	90	41	groups	group	NOUN
bjos-8676163	90	42	.	.	PUNCT
bjos-8676163	91	1	commercial	commercial	ADJ
bjos-8676163	91	2	dextranase	dextranase	PROPN
bjos-8676163	91	3	commercial	commercial	ADJ
bjos-8676163	91	4	dextranase	dextranase	NOUN
bjos-8676163	91	5	denatureddextranase	denatureddextranase	NOUN
bjos-8676163	91	6	denatured	denature	VERB
bjos-8676163	91	7	cdm	cdm	PROPN
bjos-8676163	91	8	cdm	cdm	PROPN
bjos-8676163	92	1	+	+	CCONJ
bjos-8676163	92	2	s.	s.	PROPN
bjos-8676163	92	3	mutans	mutans	PROPN
bjos-8676163	92	4	cdm	cdm	PROPN
bjos-8676163	92	5	+	+	CCONJ
bjos-8676163	92	6	s.	s.	PROPN
bjos-8676163	92	7	mutans	mutans	PROPN
bjos-8676163	92	8	+	+	CCONJ
bjos-8676163	92	9	luciferin	luciferin	PROPN
bjos-8676163	92	10	cdm	cdm	PROPN
bjos-8676163	92	11	+	+	CCONJ
bjos-8676163	92	12	s.	s.	PROPN
bjos-8676163	92	13	mutans	mutans	PROPN
bjos-8676163	92	14	+	+	CCONJ
bjos-8676163	92	15	luciferin	luciferin	PROPN
bjos-8676163	92	16	cdm	cdm	PROPN
bjos-8676163	92	17	+	+	CCONJ
bjos-8676163	92	18	s.	s.	PROPN
bjos-8676163	92	19	mutans	mutans	PROPN
bjos-8676163	92	20	cdm	cdm	PROPN
bjos-8676163	92	21	mutanase	mutanase	PROPN
bjos-8676163	92	22	mutanase	mutanase	PROPN
bjos-8676163	92	23	denatured	denature	VERB
bjos-8676163	92	24	dextranase	dextranase	NOUN
bjos-8676163	92	25	dextranase	dextranase	NOUN
bjos-8676163	92	26	denatured	denature	VERB
bjos-8676163	92	27	commercial	commercial	ADJ
bjos-8676163	92	28	dextranase	dextranase	NOUN
bjos-8676163	92	29	commercial	commercial	ADJ
bjos-8676163	92	30	dextranase	dextranase	NOUN
bjos-8676163	92	31	denatured	denature	VERB
bjos-8676163	92	32	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	92	33	0.12	0.12	NUM
bjos-8676163	92	34	%	%	NOUN
bjos-8676163	92	35	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	92	36	0.12	0.12	NUM
bjos-8676163	92	37	%	%	NOUN
bjos-8676163	92	38	b	b	NOUN
bjos-8676163	92	39	0	0	NUM
bjos-8676163	92	40	10	10	NUM
bjos-8676163	92	41	20	20	NUM
bjos-8676163	92	42	30	30	NUM
bjos-8676163	92	43	40	40	NUM
bjos-8676163	93	1	auc	auc	NOUN
bjos-8676163	93	2	log	log	NOUN
bjos-8676163	93	3	rlu	rlu	PROPN
bjos-8676163	93	4	(	(	PUNCT
bjos-8676163	93	5	relative	relative	ADJ
bjos-8676163	93	6	light	light	ADJ
bjos-8676163	93	7	unit)xh	unit)xh	ADJ
bjos-8676163	93	8	figure	figure	NOUN
bjos-8676163	93	9	2	2	NUM
bjos-8676163	93	10	.	.	NOUN
bjos-8676163	93	11	relative	relative	ADJ
bjos-8676163	93	12	light	light	ADJ
bjos-8676163	93	13	unit	unit	NOUN
bjos-8676163	93	14	(	(	PUNCT
bjos-8676163	93	15	rlu	rlu	NOUN
bjos-8676163	93	16	)	)	PUNCT
bjos-8676163	93	17	quantification	quantification	NOUN
bjos-8676163	93	18	(	(	PUNCT
bjos-8676163	93	19	log	log	NOUN
bjos-8676163	93	20	)	)	PUNCT
bjos-8676163	93	21	.	.	PUNCT
bjos-8676163	94	1	a.	a.	PROPN
bjos-8676163	94	2	s.	s.	PROPN
bjos-8676163	94	3	mutans	mutan	VERB
bjos-8676163	94	4	10	10	NUM
bjos-8676163	94	5	h	h	NOUN
bjos-8676163	94	6	-	-	PUNCT
bjos-8676163	94	7	growth	growth	NOUN
bjos-8676163	94	8	curve	curve	NOUN
bjos-8676163	94	9	(	(	PUNCT
bjos-8676163	94	10	n=3	n=3	NOUN
bjos-8676163	94	11	;	;	PUNCT
bjos-8676163	94	12	mean	mean	NOUN
bjos-8676163	94	13	±	±	NUM
bjos-8676163	94	14	sd	sd	NOUN
bjos-8676163	94	15	)	)	PUNCT
bjos-8676163	94	16	according	accord	VERB
bjos-8676163	94	17	to	to	ADP
bjos-8676163	94	18	the	the	DET
bjos-8676163	94	19	treatments	treatment	NOUN
bjos-8676163	94	20	.	.	PUNCT
bjos-8676163	95	1	b.	b.	PROPN
bjos-8676163	95	2	area	area	PROPN
bjos-8676163	95	3	under	under	ADP
bjos-8676163	95	4	the	the	DET
bjos-8676163	95	5	curve	curve	NOUN
bjos-8676163	95	6	for	for	ADP
bjos-8676163	95	7	rlu	rlu	PROPN
bjos-8676163	95	8	x	x	X
bjos-8676163	95	9	h.	h.	PROPN
bjos-8676163	95	10	*	*	PUNCT
bjos-8676163	95	11	means	mean	VERB
bjos-8676163	95	12	significant	significant	ADJ
bjos-8676163	95	13	differences	difference	NOUN
bjos-8676163	95	14	against	against	ADP
bjos-8676163	95	15	cdm	cdm	PROPN
bjos-8676163	95	16	+	+	CCONJ
bjos-8676163	95	17	s.	s.	PROPN
bjos-8676163	95	18	mutans	mutans	PROPN
bjos-8676163	95	19	+	+	CCONJ
bjos-8676163	95	20	luciferin	luciferin	PROPN
bjos-8676163	95	21	control	control	NOUN
bjos-8676163	95	22	group	group	NOUN
bjos-8676163	95	23	.	.	PUNCT
bjos-8676163	96	1	discussion	discussion	NOUN
bjos-8676163	96	2	the	the	DET
bjos-8676163	96	3	great	great	ADJ
bjos-8676163	96	4	advantage	advantage	NOUN
bjos-8676163	96	5	of	of	ADP
bjos-8676163	96	6	employing	employ	VERB
bjos-8676163	96	7	enzymes	enzyme	NOUN
bjos-8676163	96	8	for	for	ADP
bjos-8676163	96	9	biofilm	biofilm	NOUN
bjos-8676163	96	10	control	control	NOUN
bjos-8676163	96	11	lies	lie	VERB
bjos-8676163	96	12	in	in	ADP
bjos-8676163	96	13	their	their	PRON
bjos-8676163	96	14	ability	ability	NOUN
bjos-8676163	96	15	to	to	PART
bjos-8676163	96	16	target	target	VERB
bjos-8676163	96	17	specific	specific	ADJ
bjos-8676163	96	18	molecules	molecule	NOUN
bjos-8676163	96	19	,	,	PUNCT
bjos-8676163	96	20	thereby	thereby	ADV
bjos-8676163	96	21	preventing	prevent	VERB
bjos-8676163	96	22	the	the	DET
bjos-8676163	96	23	formation	formation	NOUN
bjos-8676163	96	24	or	or	CCONJ
bjos-8676163	96	25	disruption	disruption	NOUN
bjos-8676163	96	26	of	of	ADP
bjos-8676163	96	27	the	the	DET
bjos-8676163	96	28	biofilm	biofilm	NOUN
bjos-8676163	96	29	structure	structure	NOUN
bjos-8676163	96	30	,	,	PUNCT
bjos-8676163	96	31	without	without	ADP
bjos-8676163	96	32	directly	directly	ADV
bjos-8676163	96	33	interfering	interfere	VERB
bjos-8676163	96	34	with	with	ADP
bjos-8676163	96	35	microbial	microbial	ADJ
bjos-8676163	96	36	viability	viability	NOUN
bjos-8676163	96	37	.	.	PUNCT
bjos-8676163	97	1	in	in	ADP
bjos-8676163	97	2	the	the	DET
bjos-8676163	97	3	context	context	NOUN
bjos-8676163	97	4	of	of	ADP
bjos-8676163	97	5	oral	oral	ADJ
bjos-8676163	97	6	biofilms	biofilm	NOUN
bjos-8676163	97	7	,	,	PUNCT
bjos-8676163	97	8	it	it	PRON
bjos-8676163	97	9	is	be	AUX
bjos-8676163	97	10	expected	expect	VERB
bjos-8676163	97	11	that	that	SCONJ
bjos-8676163	97	12	mutanases	mutanase	NOUN
bjos-8676163	97	13	target	target	VERB
bjos-8676163	97	14	mutans	mutan	NOUN
bjos-8676163	97	15	,	,	PUNCT
bjos-8676163	97	16	while	while	SCONJ
bjos-8676163	97	17	dextranases	dextranase	NOUN
bjos-8676163	97	18	target	target	VERB
bjos-8676163	97	19	dextrans	dextran	NOUN
bjos-8676163	97	20	.	.	PUNCT
bjos-8676163	98	1	therefore	therefore	ADV
bjos-8676163	98	2	,	,	PUNCT
bjos-8676163	98	3	the	the	DET
bjos-8676163	98	4	use	use	NOUN
bjos-8676163	98	5	of	of	ADP
bjos-8676163	98	6	such	such	ADJ
bjos-8676163	98	7	enzymes	enzyme	NOUN
bjos-8676163	98	8	to	to	PART
bjos-8676163	98	9	control	control	VERB
bjos-8676163	98	10	oral	oral	ADJ
bjos-8676163	98	11	biofilms	biofilm	NOUN
bjos-8676163	98	12	could	could	AUX
bjos-8676163	98	13	offer	offer	VERB
bjos-8676163	98	14	a	a	DET
bjos-8676163	98	15	beneficial	beneficial	ADJ
bjos-8676163	98	16	therapy	therapy	NOUN
bjos-8676163	98	17	without	without	ADP
bjos-8676163	98	18	disrupting	disrupt	VERB
bjos-8676163	98	19	the	the	DET
bjos-8676163	98	20	biological	biological	ADJ
bjos-8676163	98	21	balance	balance	NOUN
bjos-8676163	98	22	in	in	ADP
bjos-8676163	98	23	the	the	DET
bjos-8676163	98	24	oral	oral	ADJ
bjos-8676163	98	25	microbiota	microbiota	NOUN
bjos-8676163	98	26	through	through	ADP
bjos-8676163	98	27	antimicrobial	antimicrobial	ADJ
bjos-8676163	98	28	effects	effect	NOUN
bjos-8676163	98	29	.	.	PUNCT
bjos-8676163	99	1	the	the	DET
bjos-8676163	99	2	newly	newly	ADV
bjos-8676163	99	3	discovered	discover	VERB
bjos-8676163	99	4	and	and	CCONJ
bjos-8676163	99	5	characterized	characterize	VERB
bjos-8676163	99	6	mutanase	mutanase	NOUN
bjos-8676163	99	7	from	from	ADP
bjos-8676163	99	8	prevotella	prevotella	NOUN
bjos-8676163	99	9	melaninogenica	melaninogenica	PROPN
bjos-8676163	99	10	and	and	CCONJ
bjos-8676163	99	11	the	the	DET
bjos-8676163	99	12	dextranase	dextranase	NOUN
bjos-8676163	99	13	from	from	ADP
bjos-8676163	99	14	capnocytophaga	capnocytophaga	PROPN
bjos-8676163	99	15	ochracea	ochracea	PROPN
bjos-8676163	99	16	have	have	AUX
bjos-8676163	99	17	been	be	AUX
bjos-8676163	99	18	used	use	VERB
bjos-8676163	99	19	7	7	NUM
bjos-8676163	99	20	queiroz	queiroz	ADV
bjos-8676163	99	21	et	et	PROPN
bjos-8676163	100	1	al	al	PROPN
bjos-8676163	100	2	.	.	PROPN
bjos-8676163	100	3	braz	braz	PROPN
bjos-8676163	100	4	j	j	PROPN
bjos-8676163	100	5	oral	oral	PROPN
bjos-8676163	100	6	sci	sci	PROPN
bjos-8676163	100	7	.	.	PUNCT
bjos-8676163	101	1	2024;23	2024;23	NUM
bjos-8676163	101	2	:	:	PUNCT
bjos-8676163	101	3	e246163	e246163	NOUN
bjos-8676163	101	4	by	by	ADP
bjos-8676163	101	5	our	our	PRON
bjos-8676163	101	6	group	group	NOUN
bjos-8676163	101	7	to	to	PART
bjos-8676163	101	8	degrade	degrade	VERB
bjos-8676163	101	9	s.	s.	PROPN
bjos-8676163	101	10	mutans	mutans	PROPN
bjos-8676163	101	11	biofilms10	biofilms10	NOUN
bjos-8676163	101	12	-	-	PUNCT
bjos-8676163	101	13	11	11	NUM
bjos-8676163	101	14	.	.	PUNCT
bjos-8676163	102	1	in	in	ADP
bjos-8676163	102	2	this	this	DET
bjos-8676163	102	3	study	study	NOUN
bjos-8676163	102	4	,	,	PUNCT
bjos-8676163	102	5	we	we	PRON
bjos-8676163	102	6	confirmed	confirm	VERB
bjos-8676163	102	7	that	that	SCONJ
bjos-8676163	102	8	these	these	DET
bjos-8676163	102	9	enzymes	enzyme	NOUN
bjos-8676163	102	10	do	do	AUX
bjos-8676163	102	11	not	not	PART
bjos-8676163	102	12	exhibit	exhibit	VERB
bjos-8676163	102	13	antimicrobial	antimicrobial	ADJ
bjos-8676163	102	14	effects	effect	NOUN
bjos-8676163	102	15	on	on	ADP
bjos-8676163	102	16	s.	s.	PROPN
bjos-8676163	102	17	mutans	mutans	PROPN
bjos-8676163	102	18	cultures	culture	NOUN
bjos-8676163	102	19	,	,	PUNCT
bjos-8676163	102	20	highlighting	highlight	VERB
bjos-8676163	102	21	their	their	PRON
bjos-8676163	102	22	potential	potential	NOUN
bjos-8676163	102	23	to	to	PART
bjos-8676163	102	24	degrade	degrade	VERB
bjos-8676163	102	25	oral	oral	ADJ
bjos-8676163	102	26	biofilms	biofilm	NOUN
bjos-8676163	102	27	solely	solely	ADV
bjos-8676163	102	28	through	through	ADP
bjos-8676163	102	29	specific	specific	ADJ
bjos-8676163	102	30	hydrolytic	hydrolytic	ADJ
bjos-8676163	102	31	action	action	NOUN
bjos-8676163	102	32	which	which	PRON
bjos-8676163	102	33	was	be	AUX
bjos-8676163	102	34	verified	verify	VERB
bjos-8676163	102	35	previously10	previously10	NOUN
bjos-8676163	102	36	-	-	PUNCT
bjos-8676163	102	37	11	11	NUM
bjos-8676163	102	38	.	.	PUNCT
bjos-8676163	103	1	the	the	DET
bjos-8676163	103	2	lack	lack	NOUN
bjos-8676163	103	3	of	of	ADP
bjos-8676163	103	4	antimicrobial	antimicrobial	ADJ
bjos-8676163	103	5	effect	effect	NOUN
bjos-8676163	103	6	for	for	ADP
bjos-8676163	103	7	the	the	DET
bjos-8676163	103	8	recombinant	recombinant	ADJ
bjos-8676163	103	9	enzymes	enzyme	NOUN
bjos-8676163	103	10	aligns	align	VERB
bjos-8676163	103	11	with	with	ADP
bjos-8676163	103	12	findings	finding	NOUN
bjos-8676163	103	13	by	by	ADP
bjos-8676163	103	14	rikvold	rikvold	ADJ
bjos-8676163	103	15	et	et	PROPN
bjos-8676163	103	16	al.16	al.16	PROPN
bjos-8676163	103	17	(	(	PUNCT
bjos-8676163	103	18	2024	2024	NUM
bjos-8676163	103	19	)	)	PUNCT
bjos-8676163	103	20	that	that	PRON
bjos-8676163	103	21	also	also	ADV
bjos-8676163	103	22	evaluated	evaluate	VERB
bjos-8676163	103	23	the	the	DET
bjos-8676163	103	24	antimicrobial	antimicrobial	ADJ
bjos-8676163	103	25	effects	effect	NOUN
bjos-8676163	103	26	of	of	ADP
bjos-8676163	103	27	mutanase	mutanase	NOUN
bjos-8676163	103	28	,	,	PUNCT
bjos-8676163	103	29	dnase	dnase	NOUN
bjos-8676163	103	30	,	,	PUNCT
bjos-8676163	103	31	and	and	CCONJ
bjos-8676163	103	32	beta	beta	NOUN
bjos-8676163	103	33	-	-	PUNCT
bjos-8676163	103	34	glucanase	glucanase	NOUN
bjos-8676163	103	35	.	.	PUNCT
bjos-8676163	104	1	in	in	ADP
bjos-8676163	104	2	this	this	DET
bjos-8676163	104	3	context	context	NOUN
bjos-8676163	104	4	,	,	PUNCT
bjos-8676163	104	5	the	the	DET
bjos-8676163	104	6	observed	observed	ADJ
bjos-8676163	104	7	reduction	reduction	NOUN
bjos-8676163	104	8	of	of	ADP
bjos-8676163	104	9	viability	viability	NOUN
bjos-8676163	104	10	in	in	ADP
bjos-8676163	104	11	enzymatically	enzymatically	ADV
bjos-8676163	104	12	treated	treat	VERB
bjos-8676163	104	13	biofilms4,6	biofilms4,6	NOUN
bjos-8676163	104	14	may	may	AUX
bjos-8676163	104	15	be	be	AUX
bjos-8676163	104	16	attributed	attribute	VERB
bjos-8676163	104	17	to	to	ADP
bjos-8676163	104	18	the	the	DET
bjos-8676163	104	19	degradation	degradation	NOUN
bjos-8676163	104	20	of	of	ADP
bjos-8676163	104	21	extracellular	extracellular	ADJ
bjos-8676163	104	22	polymeric	polymeric	ADJ
bjos-8676163	104	23	substances	substance	NOUN
bjos-8676163	104	24	,	,	PUNCT
bjos-8676163	104	25	which	which	PRON
bjos-8676163	104	26	impairs	impair	VERB
bjos-8676163	104	27	bacterial	bacterial	ADJ
bjos-8676163	104	28	aggregation	aggregation	NOUN
bjos-8676163	104	29	during	during	ADP
bjos-8676163	104	30	biofilm	biofilm	NOUN
bjos-8676163	104	31	formation	formation	NOUN
bjos-8676163	104	32	or	or	CCONJ
bjos-8676163	104	33	detaches	detach	VERB
bjos-8676163	104	34	bacterial	bacterial	ADJ
bjos-8676163	104	35	cells	cell	NOUN
bjos-8676163	104	36	from	from	ADP
bjos-8676163	104	37	already	already	ADV
bjos-8676163	104	38	formed	form	VERB
bjos-8676163	104	39	biofilms	biofilm	NOUN
bjos-8676163	104	40	.	.	PUNCT
bjos-8676163	105	1	our	our	PRON
bjos-8676163	105	2	study	study	NOUN
bjos-8676163	105	3	supports	support	VERB
bjos-8676163	105	4	this	this	DET
bjos-8676163	105	5	hypothesis	hypothesis	NOUN
bjos-8676163	105	6	,	,	PUNCT
bjos-8676163	105	7	as	as	SCONJ
bjos-8676163	105	8	the	the	DET
bjos-8676163	105	9	recombinant	recombinant	ADJ
bjos-8676163	105	10	enzymes	enzyme	NOUN
bjos-8676163	105	11	did	do	AUX
bjos-8676163	105	12	not	not	PART
bjos-8676163	105	13	affect	affect	VERB
bjos-8676163	105	14	the	the	DET
bjos-8676163	105	15	planktonic	planktonic	ADJ
bjos-8676163	105	16	growth	growth	NOUN
bjos-8676163	105	17	of	of	ADP
bjos-8676163	105	18	s.	s.	PROPN
bjos-8676163	105	19	mutans	mutans	PROPN
bjos-8676163	105	20	(	(	PUNCT
bjos-8676163	105	21	fig	fig	NOUN
bjos-8676163	105	22	.	.	NOUN
bjos-8676163	105	23	1	1	NUM
bjos-8676163	105	24	and	and	CCONJ
bjos-8676163	105	25	2	2	NUM
bjos-8676163	105	26	)	)	PUNCT
bjos-8676163	105	27	,	,	PUNCT
bjos-8676163	105	28	which	which	PRON
bjos-8676163	105	29	has	have	AUX
bjos-8676163	105	30	been	be	AUX
bjos-8676163	105	31	considered	consider	VERB
bjos-8676163	105	32	one	one	NUM
bjos-8676163	105	33	thousand	thousand	NUM
bjos-8676163	105	34	more	more	ADV
bjos-8676163	105	35	susceptible	susceptible	ADJ
bjos-8676163	105	36	to	to	ADP
bjos-8676163	105	37	antimicrobials	antimicrobial	NOUN
bjos-8676163	105	38	in	in	ADP
bjos-8676163	105	39	its	its	PRON
bjos-8676163	105	40	planktonic	planktonic	NOUN
bjos-8676163	105	41	than	than	ADP
bjos-8676163	105	42	in	in	ADP
bjos-8676163	105	43	biofilms17,18	biofilms17,18	PROPN
bjos-8676163	105	44	.	.	PUNCT
bjos-8676163	106	1	differently	differently	ADV
bjos-8676163	106	2	,	,	PUNCT
bjos-8676163	106	3	commercial	commercial	ADJ
bjos-8676163	106	4	dextranase	dextranase	NOUN
bjos-8676163	106	5	exhibited	exhibit	VERB
bjos-8676163	106	6	a	a	DET
bjos-8676163	106	7	similar	similar	ADJ
bjos-8676163	106	8	inhibition	inhibition	NOUN
bjos-8676163	106	9	of	of	ADP
bjos-8676163	106	10	bacterial	bacterial	ADJ
bjos-8676163	106	11	growth	growth	NOUN
bjos-8676163	106	12	as	as	ADP
bjos-8676163	106	13	digluconate	digluconate	NOUN
bjos-8676163	106	14	chlorhexidine	chlorhexidine	NOUN
bjos-8676163	106	15	(	(	PUNCT
bjos-8676163	106	16	fig	fig	NOUN
bjos-8676163	106	17	.	.	NOUN
bjos-8676163	106	18	1	1	NUM
bjos-8676163	106	19	and	and	CCONJ
bjos-8676163	106	20	2	2	NUM
bjos-8676163	106	21	)	)	PUNCT
bjos-8676163	106	22	.	.	PUNCT
bjos-8676163	107	1	however	however	ADV
bjos-8676163	107	2	,	,	PUNCT
bjos-8676163	107	3	when	when	SCONJ
bjos-8676163	107	4	the	the	DET
bjos-8676163	107	5	commercial	commercial	ADJ
bjos-8676163	107	6	dextranase	dextranase	NOUN
bjos-8676163	107	7	was	be	AUX
bjos-8676163	107	8	heated	heated	ADJ
bjos-8676163	107	9	-	-	PUNCT
bjos-8676163	107	10	denatured	denature	VERB
bjos-8676163	107	11	,	,	PUNCT
bjos-8676163	107	12	bacterial	bacterial	ADJ
bjos-8676163	107	13	growth	growth	NOUN
bjos-8676163	107	14	occurred	occur	VERB
bjos-8676163	107	15	similarly	similarly	ADV
bjos-8676163	107	16	to	to	ADP
bjos-8676163	107	17	the	the	DET
bjos-8676163	107	18	untreated	untreated	ADJ
bjos-8676163	107	19	group	group	NOUN
bjos-8676163	107	20	.	.	PUNCT
bjos-8676163	108	1	thus	thus	ADV
bjos-8676163	108	2	,	,	PUNCT
bjos-8676163	108	3	it	it	PRON
bjos-8676163	108	4	could	could	AUX
bjos-8676163	108	5	be	be	AUX
bjos-8676163	108	6	speculated	speculate	VERB
bjos-8676163	108	7	a	a	DET
bjos-8676163	108	8	possible	possible	ADJ
bjos-8676163	108	9	antimicrobial	antimicrobial	ADJ
bjos-8676163	108	10	effect	effect	NOUN
bjos-8676163	108	11	of	of	ADP
bjos-8676163	108	12	commercial	commercial	ADJ
bjos-8676163	108	13	dextranase	dextranase	NOUN
bjos-8676163	108	14	.	.	PUNCT
bjos-8676163	109	1	however	however	ADV
bjos-8676163	109	2	,	,	PUNCT
bjos-8676163	109	3	the	the	DET
bjos-8676163	109	4	substrate	substrate	NOUN
bjos-8676163	109	5	-	-	PUNCT
bjos-8676163	109	6	specificity	specificity	NOUN
bjos-8676163	109	7	action	action	NOUN
bjos-8676163	109	8	of	of	ADP
bjos-8676163	109	9	such	such	ADJ
bjos-8676163	109	10	enzymes	enzyme	NOUN
bjos-8676163	109	11	for	for	ADP
bjos-8676163	109	12	the	the	DET
bjos-8676163	109	13	recombinant	recombinant	ADJ
bjos-8676163	109	14	enzymes	enzyme	NOUN
bjos-8676163	109	15	,	,	PUNCT
bjos-8676163	109	16	as	as	SCONJ
bjos-8676163	109	17	observed	observe	VERB
bjos-8676163	109	18	in	in	ADP
bjos-8676163	109	19	our	our	PRON
bjos-8676163	109	20	study	study	NOUN
bjos-8676163	109	21	and	and	CCONJ
bjos-8676163	109	22	the	the	DET
bjos-8676163	109	23	reported	report	VERB
bjos-8676163	109	24	by	by	ADP
bjos-8676163	109	25	rikvold	rikvold	PROPN
bjos-8676163	109	26	et	et	PROPN
bjos-8676163	109	27	al.16	al.16	PROPN
bjos-8676163	109	28	(	(	PUNCT
bjos-8676163	109	29	2024	2024	NUM
bjos-8676163	109	30	)	)	PUNCT
bjos-8676163	109	31	,	,	PUNCT
bjos-8676163	109	32	do	do	AUX
bjos-8676163	109	33	not	not	PART
bjos-8676163	109	34	support	support	VERB
bjos-8676163	109	35	this	this	DET
bjos-8676163	109	36	hypothesis	hypothesis	NOUN
bjos-8676163	109	37	.	.	PUNCT
bjos-8676163	110	1	additionally	additionally	ADV
bjos-8676163	110	2	,	,	PUNCT
bjos-8676163	110	3	s.	s.	PROPN
bjos-8676163	110	4	mutans	mutans	PROPN
bjos-8676163	110	5	cultures	culture	NOUN
bjos-8676163	110	6	were	be	AUX
bjos-8676163	110	7	grown	grow	VERB
bjos-8676163	110	8	in	in	ADP
bjos-8676163	110	9	a	a	DET
bjos-8676163	110	10	chemically	chemically	ADV
bjos-8676163	110	11	defined	define	VERB
bjos-8676163	110	12	medium	medium	ADJ
bjos-8676163	110	13	(	(	PUNCT
bjos-8676163	110	14	cdm	cdm	NOUN
bjos-8676163	110	15	)	)	PUNCT
bjos-8676163	110	16	supplemented	supplement	VERB
bjos-8676163	110	17	with	with	ADP
bjos-8676163	110	18	glucose	glucose	NOUN
bjos-8676163	110	19	instead	instead	ADV
bjos-8676163	110	20	of	of	ADP
bjos-8676163	110	21	sucrose	sucrose	PROPN
bjos-8676163	110	22	,	,	PUNCT
bjos-8676163	110	23	which	which	PRON
bjos-8676163	110	24	can	can	AUX
bjos-8676163	110	25	not	not	PART
bjos-8676163	110	26	lead	lead	VERB
bjos-8676163	110	27	to	to	ADP
bjos-8676163	110	28	the	the	DET
bjos-8676163	110	29	synthesis	synthesis	NOUN
bjos-8676163	110	30	of	of	ADP
bjos-8676163	110	31	exopolysaccharides	exopolysaccharide	NOUN
bjos-8676163	110	32	such	such	ADJ
bjos-8676163	110	33	as	as	ADP
bjos-8676163	110	34	dextran	dextran	NOUN
bjos-8676163	110	35	and	and	CCONJ
bjos-8676163	110	36	mutan	mutan	ADJ
bjos-8676163	110	37	that	that	PRON
bjos-8676163	110	38	comprise	comprise	VERB
bjos-8676163	110	39	the	the	DET
bjos-8676163	110	40	biofilm	biofilm	NOUN
bjos-8676163	110	41	matrix	matrix	NOUN
bjos-8676163	110	42	.	.	PUNCT
bjos-8676163	111	1	as	as	ADP
bjos-8676163	111	2	a	a	DET
bjos-8676163	111	3	result	result	NOUN
bjos-8676163	111	4	,	,	PUNCT
bjos-8676163	111	5	the	the	DET
bjos-8676163	111	6	antimicrobial	antimicrobial	ADJ
bjos-8676163	111	7	effect	effect	NOUN
bjos-8676163	111	8	could	could	AUX
bjos-8676163	111	9	also	also	ADV
bjos-8676163	111	10	not	not	PART
bjos-8676163	111	11	be	be	AUX
bjos-8676163	111	12	due	due	ADJ
bjos-8676163	111	13	to	to	ADP
bjos-8676163	111	14	eps	eps	PROPN
bjos-8676163	111	15	protection	protection	NOUN
bjos-8676163	111	16	.	.	PUNCT
bjos-8676163	112	1	thus	thus	ADV
bjos-8676163	112	2	,	,	PUNCT
bjos-8676163	112	3	the	the	DET
bjos-8676163	112	4	absence	absence	NOUN
bjos-8676163	112	5	of	of	ADP
bjos-8676163	112	6	enzymatic	enzymatic	ADJ
bjos-8676163	112	7	activity	activity	NOUN
bjos-8676163	112	8	observed	observe	VERB
bjos-8676163	112	9	in	in	ADP
bjos-8676163	112	10	this	this	DET
bjos-8676163	112	11	experiment	experiment	NOUN
bjos-8676163	112	12	could	could	AUX
bjos-8676163	112	13	be	be	AUX
bjos-8676163	112	14	attributed	attribute	VERB
bjos-8676163	112	15	both	both	PRON
bjos-8676163	112	16	to	to	ADP
bjos-8676163	112	17	the	the	DET
bjos-8676163	112	18	lack	lack	NOUN
bjos-8676163	112	19	of	of	ADP
bjos-8676163	112	20	available	available	ADJ
bjos-8676163	112	21	substrate	substrate	NOUN
bjos-8676163	112	22	and	and	CCONJ
bjos-8676163	112	23	the	the	DET
bjos-8676163	112	24	enzymes	enzyme	NOUN
bjos-8676163	112	25	’	'	PUNCT
bjos-8676163	112	26	inability	inability	NOUN
bjos-8676163	112	27	to	to	PART
bjos-8676163	112	28	exert	exert	VERB
bjos-8676163	112	29	antibacterial	antibacterial	ADJ
bjos-8676163	112	30	effects	effect	NOUN
bjos-8676163	112	31	.	.	PUNCT
bjos-8676163	113	1	a	a	DET
bjos-8676163	113	2	more	more	ADV
bjos-8676163	113	3	plausible	plausible	ADJ
bjos-8676163	113	4	explanation	explanation	NOUN
bjos-8676163	113	5	would	would	AUX
bjos-8676163	113	6	be	be	AUX
bjos-8676163	113	7	contaminants	contaminant	NOUN
bjos-8676163	113	8	in	in	ADP
bjos-8676163	113	9	the	the	DET
bjos-8676163	113	10	lyophilized	lyophilized	ADJ
bjos-8676163	113	11	enzyme	enzyme	NOUN
bjos-8676163	113	12	product	product	NOUN
bjos-8676163	113	13	that	that	PRON
bjos-8676163	113	14	could	could	AUX
bjos-8676163	113	15	affect	affect	VERB
bjos-8676163	113	16	the	the	DET
bjos-8676163	113	17	bacterial	bacterial	ADJ
bjos-8676163	113	18	viability	viability	NOUN
bjos-8676163	113	19	.	.	PUNCT
bjos-8676163	114	1	indeed	indeed	ADV
bjos-8676163	114	2	,	,	PUNCT
bjos-8676163	114	3	the	the	DET
bjos-8676163	114	4	certificate	certificate	NOUN
bjos-8676163	114	5	of	of	ADP
bjos-8676163	114	6	analyses	analysis	NOUN
bjos-8676163	114	7	of	of	ADP
bjos-8676163	114	8	the	the	DET
bjos-8676163	114	9	commercial	commercial	ADJ
bjos-8676163	114	10	dextranase	dextranase	NOUN
bjos-8676163	114	11	does	do	AUX
bjos-8676163	114	12	not	not	PART
bjos-8676163	114	13	offer	offer	VERB
bjos-8676163	114	14	details	detail	NOUN
bjos-8676163	114	15	regarding	regard	VERB
bjos-8676163	114	16	the	the	DET
bjos-8676163	114	17	enzyme	enzyme	NOUN
bjos-8676163	114	18	’s	’s	PART
bjos-8676163	114	19	production	production	NOUN
bjos-8676163	114	20	or	or	CCONJ
bjos-8676163	114	21	purification	purification	NOUN
bjos-8676163	114	22	process	process	NOUN
bjos-8676163	114	23	.	.	PUNCT
bjos-8676163	115	1	in	in	ADP
bjos-8676163	115	2	fact	fact	NOUN
bjos-8676163	115	3	,	,	PUNCT
bjos-8676163	115	4	it	it	PRON
bjos-8676163	115	5	states	state	VERB
bjos-8676163	115	6	that	that	SCONJ
bjos-8676163	115	7	the	the	DET
bjos-8676163	115	8	protein	protein	NOUN
bjos-8676163	115	9	content	content	NOUN
bjos-8676163	115	10	is	be	AUX
bjos-8676163	115	11	20.85	20.85	NUM
bjos-8676163	115	12	%	%	NOUN
bjos-8676163	115	13	of	of	ADP
bjos-8676163	115	14	the	the	DET
bjos-8676163	115	15	whole	whole	ADJ
bjos-8676163	115	16	product	product	NOUN
bjos-8676163	115	17	.	.	PUNCT
bjos-8676163	116	1	however	however	ADV
bjos-8676163	116	2	,	,	PUNCT
bjos-8676163	116	3	it	it	PRON
bjos-8676163	116	4	is	be	AUX
bjos-8676163	116	5	unclear	unclear	ADJ
bjos-8676163	116	6	whether	whether	SCONJ
bjos-8676163	116	7	this	this	DET
bjos-8676163	116	8	percentage	percentage	NOUN
bjos-8676163	116	9	specifically	specifically	ADV
bjos-8676163	116	10	refers	refer	VERB
bjos-8676163	116	11	to	to	ADP
bjos-8676163	116	12	the	the	DET
bjos-8676163	116	13	dextranase	dextranase	NOUN
bjos-8676163	116	14	,	,	PUNCT
bjos-8676163	116	15	as	as	SCONJ
bjos-8676163	116	16	the	the	DET
bjos-8676163	116	17	total	total	ADJ
bjos-8676163	116	18	protein	protein	NOUN
bjos-8676163	116	19	content	content	NOUN
bjos-8676163	116	20	was	be	AUX
bjos-8676163	116	21	quantified	quantify	VERB
bjos-8676163	116	22	using	use	VERB
bjos-8676163	116	23	lowry	lowry	PROPN
bjos-8676163	116	24	’s	’s	PART
bjos-8676163	116	25	method19	method19	NOUN
bjos-8676163	116	26	.	.	PUNCT
bjos-8676163	117	1	additionally	additionally	ADV
bjos-8676163	117	2	,	,	PUNCT
bjos-8676163	117	3	fungal	fungal	ADJ
bjos-8676163	117	4	dextranases	dextranase	NOUN
bjos-8676163	117	5	are	be	AUX
bjos-8676163	117	6	known	know	VERB
bjos-8676163	117	7	to	to	PART
bjos-8676163	117	8	be	be	AUX
bjos-8676163	117	9	produced	produce	VERB
bjos-8676163	117	10	by	by	ADP
bjos-8676163	117	11	induction	induction	NOUN
bjos-8676163	117	12	methods3	methods3	PROPN
bjos-8676163	117	13	where	where	SCONJ
bjos-8676163	117	14	the	the	DET
bjos-8676163	117	15	enzyme	enzyme	NOUN
bjos-8676163	117	16	is	be	AUX
bjos-8676163	117	17	secreted	secrete	VERB
bjos-8676163	117	18	extracellularly	extracellularly	ADV
bjos-8676163	117	19	along	along	ADV
bjos-8676163	117	20	with	with	ADP
bjos-8676163	117	21	many	many	ADJ
bjos-8676163	117	22	others	other	NOUN
bjos-8676163	117	23	fungal	fungal	ADJ
bjos-8676163	117	24	products	product	NOUN
bjos-8676163	117	25	that	that	PRON
bjos-8676163	117	26	may	may	AUX
bjos-8676163	117	27	not	not	PART
bjos-8676163	117	28	be	be	AUX
bjos-8676163	117	29	removed	remove	VERB
bjos-8676163	117	30	if	if	SCONJ
bjos-8676163	117	31	enzymes	enzyme	NOUN
bjos-8676163	117	32	are	be	AUX
bjos-8676163	117	33	not	not	PART
bjos-8676163	117	34	properly	properly	ADV
bjos-8676163	117	35	purified	purify	VERB
bjos-8676163	117	36	.	.	PUNCT
bjos-8676163	118	1	considering	consider	VERB
bjos-8676163	118	2	that	that	SCONJ
bjos-8676163	118	3	the	the	DET
bjos-8676163	118	4	commercial	commercial	ADJ
bjos-8676163	118	5	dextranase	dextranase	NOUN
bjos-8676163	118	6	was	be	AUX
bjos-8676163	118	7	produced	produce	VERB
bjos-8676163	118	8	by	by	ADP
bjos-8676163	118	9	penicillium	penicillium	NOUN
bjos-8676163	118	10	spp	spp	NOUN
bjos-8676163	118	11	.	.	PUNCT
bjos-8676163	118	12	,	,	PUNCT
bjos-8676163	118	13	it	it	PRON
bjos-8676163	118	14	is	be	AUX
bjos-8676163	118	15	possible	possible	ADJ
bjos-8676163	118	16	to	to	PART
bjos-8676163	118	17	speculate	speculate	VERB
bjos-8676163	118	18	that	that	SCONJ
bjos-8676163	118	19	the	the	DET
bjos-8676163	118	20	presence	presence	NOUN
bjos-8676163	118	21	of	of	ADP
bjos-8676163	118	22	penicillin	penicillin	NOUN
bjos-8676163	118	23	as	as	ADP
bjos-8676163	118	24	a	a	DET
bjos-8676163	118	25	contaminant	contaminant	NOUN
bjos-8676163	118	26	could	could	AUX
bjos-8676163	118	27	have	have	AUX
bjos-8676163	118	28	contributed	contribute	VERB
bjos-8676163	118	29	to	to	ADP
bjos-8676163	118	30	the	the	DET
bjos-8676163	118	31	observed	observed	ADJ
bjos-8676163	118	32	antimicrobial	antimicrobial	ADJ
bjos-8676163	118	33	effect	effect	NOUN
bjos-8676163	118	34	.	.	PUNCT
bjos-8676163	119	1	in	in	ADP
bjos-8676163	119	2	contrast	contrast	NOUN
bjos-8676163	119	3	,	,	PUNCT
bjos-8676163	119	4	in	in	ADP
bjos-8676163	119	5	our	our	PRON
bjos-8676163	119	6	study	study	NOUN
bjos-8676163	119	7	,	,	PUNCT
bjos-8676163	119	8	we	we	PRON
bjos-8676163	119	9	used	use	VERB
bjos-8676163	119	10	a	a	DET
bjos-8676163	119	11	well	well	ADV
bjos-8676163	119	12	standardized	standardize	VERB
bjos-8676163	119	13	protocol	protocol	NOUN
bjos-8676163	119	14	for	for	ADP
bjos-8676163	119	15	intracellular	intracellular	ADJ
bjos-8676163	119	16	heterologous	heterologous	ADJ
bjos-8676163	119	17	expression	expression	NOUN
bjos-8676163	119	18	of	of	ADP
bjos-8676163	119	19	the	the	DET
bjos-8676163	119	20	mutanase	mutanase	NOUN
bjos-8676163	119	21	and	and	CCONJ
bjos-8676163	119	22	dextranase	dextranase	NOUN
bjos-8676163	119	23	,	,	PUNCT
bjos-8676163	119	24	as	as	ADV
bjos-8676163	119	25	well	well	ADV
bjos-8676163	119	26	as	as	ADP
bjos-8676163	119	27	for	for	ADP
bjos-8676163	119	28	protein	protein	NOUN
bjos-8676163	119	29	purification10	purification10	NOUN
bjos-8676163	119	30	-	-	PUNCT
bjos-8676163	119	31	12	12	NUM
bjos-8676163	119	32	.	.	PUNCT
bjos-8676163	120	1	it	it	PRON
bjos-8676163	120	2	is	be	AUX
bjos-8676163	120	3	worth	worth	ADJ
bjos-8676163	120	4	noting	note	VERB
bjos-8676163	120	5	that	that	SCONJ
bjos-8676163	120	6	the	the	DET
bjos-8676163	120	7	commercial	commercial	ADJ
bjos-8676163	120	8	dextranase	dextranase	NOUN
bjos-8676163	120	9	used	use	VERB
bjos-8676163	120	10	in	in	ADP
bjos-8676163	120	11	our	our	PRON
bjos-8676163	120	12	study	study	NOUN
bjos-8676163	120	13	has	have	AUX
bjos-8676163	120	14	been	be	AUX
bjos-8676163	120	15	widely	widely	ADV
bjos-8676163	120	16	utilized	utilize	VERB
bjos-8676163	120	17	in	in	ADP
bjos-8676163	120	18	studies	study	NOUN
bjos-8676163	120	19	as	as	ADP
bjos-8676163	120	20	a	a	DET
bjos-8676163	120	21	test	test	NOUN
bjos-8676163	120	22	or	or	CCONJ
bjos-8676163	120	23	control	control	VERB
bjos-8676163	120	24	enzyme	enzyme	NOUN
bjos-8676163	120	25	in	in	ADP
bjos-8676163	120	26	biofilm	biofilm	NOUN
bjos-8676163	120	27	assays4	assays4	NOUN
bjos-8676163	120	28	-	-	PUNCT
bjos-8676163	120	29	5,8	5,8	NUM
bjos-8676163	120	30	.	.	PUNCT
bjos-8676163	120	31	upon	upon	SCONJ
bjos-8676163	120	32	reviewing	review	VERB
bjos-8676163	120	33	the	the	DET
bjos-8676163	120	34	literature	literature	NOUN
bjos-8676163	120	35	,	,	PUNCT
bjos-8676163	120	36	we	we	PRON
bjos-8676163	120	37	found	find	VERB
bjos-8676163	120	38	one	one	NUM
bjos-8676163	120	39	study7	study7	NOUN
bjos-8676163	120	40	in	in	ADP
bjos-8676163	120	41	which	which	PRON
bjos-8676163	120	42	another	another	DET
bjos-8676163	120	43	commercial	commercial	ADJ
bjos-8676163	120	44	enzyme	enzyme	NOUN
bjos-8676163	120	45	was	be	AUX
bjos-8676163	120	46	employed	employ	VERB
bjos-8676163	120	47	to	to	PART
bjos-8676163	120	48	specifically	specifically	ADV
bjos-8676163	120	49	test	test	VERB
bjos-8676163	120	50	its	its	PRON
bjos-8676163	120	51	effect	effect	NOUN
bjos-8676163	120	52	on	on	ADP
bjos-8676163	120	53	the	the	DET
bjos-8676163	120	54	growth	growth	NOUN
bjos-8676163	120	55	of	of	ADP
bjos-8676163	120	56	s.	s.	PROPN
bjos-8676163	120	57	mutans	mutans	PROPN
bjos-8676163	120	58	in	in	ADP
bjos-8676163	120	59	culture	culture	NOUN
bjos-8676163	120	60	,	,	PUNCT
bjos-8676163	120	61	with	with	ADP
bjos-8676163	120	62	notable	notable	ADJ
bjos-8676163	120	63	inhibitory	inhibitory	ADJ
bjos-8676163	120	64	results	result	NOUN
bjos-8676163	120	65	.	.	PUNCT
bjos-8676163	121	1	while	while	SCONJ
bjos-8676163	121	2	this	this	PRON
bjos-8676163	121	3	may	may	AUX
bjos-8676163	121	4	be	be	AUX
bjos-8676163	121	5	a	a	DET
bjos-8676163	121	6	true	true	ADJ
bjos-8676163	121	7	effect	effect	NOUN
bjos-8676163	121	8	,	,	PUNCT
bjos-8676163	121	9	the	the	DET
bjos-8676163	121	10	purification	purification	NOUN
bjos-8676163	121	11	grade	grade	NOUN
bjos-8676163	121	12	of	of	ADP
bjos-8676163	121	13	such	such	ADJ
bjos-8676163	121	14	commercial	commercial	ADJ
bjos-8676163	121	15	enzyme	enzyme	NOUN
bjos-8676163	121	16	is	be	AUX
bjos-8676163	121	17	not	not	PART
bjos-8676163	121	18	informed	inform	VERB
bjos-8676163	121	19	and	and	CCONJ
bjos-8676163	121	20	may	may	AUX
bjos-8676163	121	21	have	have	VERB
bjos-8676163	121	22	an	an	DET
bjos-8676163	121	23	impact	impact	NOUN
bjos-8676163	121	24	on	on	ADP
bjos-8676163	121	25	its	its	PRON
bjos-8676163	121	26	observed	observed	ADJ
bjos-8676163	121	27	effects	effect	NOUN
bjos-8676163	121	28	.	.	PUNCT
bjos-8676163	122	1	8	8	NUM
bjos-8676163	122	2	queiroz	queiroz	ADV
bjos-8676163	122	3	et	et	PROPN
bjos-8676163	122	4	al	al	PROPN
bjos-8676163	122	5	.	.	PROPN
bjos-8676163	122	6	braz	braz	PROPN
bjos-8676163	122	7	j	j	PROPN
bjos-8676163	122	8	oral	oral	PROPN
bjos-8676163	122	9	sci	sci	PROPN
bjos-8676163	122	10	.	.	PUNCT
bjos-8676163	123	1	2024;23	2024;23	NUM
bjos-8676163	123	2	:	:	PUNCT
bjos-8676163	123	3	e246163	e246163	NUM
bjos-8676163	123	4	overall	overall	NOUN
bjos-8676163	123	5	,	,	PUNCT
bjos-8676163	123	6	our	our	PRON
bjos-8676163	123	7	study	study	NOUN
bjos-8676163	123	8	highlights	highlight	VERB
bjos-8676163	123	9	the	the	DET
bjos-8676163	123	10	necessity	necessity	NOUN
bjos-8676163	123	11	of	of	ADP
bjos-8676163	123	12	implementing	implement	VERB
bjos-8676163	123	13	a	a	DET
bjos-8676163	123	14	purification	purification	NOUN
bjos-8676163	123	15	step	step	NOUN
bjos-8676163	123	16	after	after	ADP
bjos-8676163	123	17	enzyme	enzyme	NOUN
bjos-8676163	123	18	production	production	NOUN
bjos-8676163	123	19	to	to	PART
bjos-8676163	123	20	ensure	ensure	VERB
bjos-8676163	123	21	the	the	DET
bjos-8676163	123	22	removal	removal	NOUN
bjos-8676163	123	23	of	of	ADP
bjos-8676163	123	24	any	any	DET
bjos-8676163	123	25	contaminants	contaminant	NOUN
bjos-8676163	123	26	that	that	PRON
bjos-8676163	123	27	may	may	AUX
bjos-8676163	123	28	not	not	PART
bjos-8676163	123	29	only	only	ADV
bjos-8676163	123	30	affect	affect	VERB
bjos-8676163	123	31	microbial	microbial	ADJ
bjos-8676163	123	32	viability	viability	NOUN
bjos-8676163	123	33	but	but	CCONJ
bjos-8676163	123	34	also	also	ADV
bjos-8676163	123	35	pose	pose	VERB
bjos-8676163	123	36	toxicity	toxicity	NOUN
bjos-8676163	123	37	risks	risk	NOUN
bjos-8676163	123	38	to	to	ADP
bjos-8676163	123	39	humans	human	NOUN
bjos-8676163	123	40	,	,	PUNCT
bjos-8676163	123	41	particularly	particularly	ADV
bjos-8676163	123	42	in	in	ADP
bjos-8676163	123	43	the	the	DET
bjos-8676163	123	44	context	context	NOUN
bjos-8676163	123	45	of	of	ADP
bjos-8676163	123	46	enzyme	enzyme	NOUN
bjos-8676163	123	47	application	application	NOUN
bjos-8676163	123	48	in	in	ADP
bjos-8676163	123	49	oral	oral	ADJ
bjos-8676163	123	50	care	care	NOUN
bjos-8676163	123	51	products	product	NOUN
bjos-8676163	123	52	.	.	PUNCT
bjos-8676163	124	1	enzymes	enzyme	NOUN
bjos-8676163	124	2	can	can	AUX
bjos-8676163	124	3	also	also	ADV
bjos-8676163	124	4	be	be	AUX
bjos-8676163	124	5	a	a	DET
bjos-8676163	124	6	desirable	desirable	ADJ
bjos-8676163	124	7	strategy	strategy	NOUN
bjos-8676163	124	8	when	when	SCONJ
bjos-8676163	124	9	antimicrobials	antimicrobial	NOUN
bjos-8676163	124	10	are	be	AUX
bjos-8676163	124	11	needed	need	VERB
bjos-8676163	124	12	.	.	PUNCT
bjos-8676163	125	1	despite	despite	SCONJ
bjos-8676163	125	2	biofilms	biofilm	NOUN
bjos-8676163	125	3	being	be	AUX
bjos-8676163	125	4	resistant	resistant	ADJ
bjos-8676163	125	5	to	to	ADP
bjos-8676163	125	6	antimicrobials17	antimicrobials17	NOUN
bjos-8676163	125	7	,	,	PUNCT
bjos-8676163	125	8	enzymes	enzyme	NOUN
bjos-8676163	125	9	may	may	AUX
bjos-8676163	125	10	play	play	VERB
bjos-8676163	125	11	a	a	DET
bjos-8676163	125	12	crucial	crucial	ADJ
bjos-8676163	125	13	role	role	NOUN
bjos-8676163	125	14	in	in	ADP
bjos-8676163	125	15	degrading	degrade	VERB
bjos-8676163	125	16	eps	ep	NOUN
bjos-8676163	125	17	,	,	PUNCT
bjos-8676163	125	18	facilitating	facilitate	VERB
bjos-8676163	125	19	antimicrobial	antimicrobial	ADJ
bjos-8676163	125	20	diffusion	diffusion	NOUN
bjos-8676163	125	21	,	,	PUNCT
bjos-8676163	125	22	and	and	CCONJ
bjos-8676163	125	23	enhancing	enhance	VERB
bjos-8676163	125	24	bacterial	bacterial	ADJ
bjos-8676163	125	25	killing4	killing4	NOUN
bjos-8676163	125	26	-	-	PUNCT
bjos-8676163	125	27	6	6	NUM
bjos-8676163	125	28	.	.	PUNCT
bjos-8676163	126	1	thus	thus	ADV
bjos-8676163	126	2	,	,	PUNCT
bjos-8676163	126	3	enzymes	enzyme	NOUN
bjos-8676163	126	4	contaminated	contaminate	VERB
bjos-8676163	126	5	with	with	ADP
bjos-8676163	126	6	antimicrobials	antimicrobial	NOUN
bjos-8676163	126	7	may	may	AUX
bjos-8676163	126	8	lead	lead	VERB
bjos-8676163	126	9	to	to	ADP
bjos-8676163	126	10	an	an	DET
bjos-8676163	126	11	overestimated	overestimated	ADJ
bjos-8676163	126	12	reduction	reduction	NOUN
bjos-8676163	126	13	in	in	ADP
bjos-8676163	126	14	bacterial	bacterial	ADJ
bjos-8676163	126	15	viability	viability	NOUN
bjos-8676163	126	16	.	.	PUNCT
bjos-8676163	127	1	besides	besides	SCONJ
bjos-8676163	127	2	,	,	PUNCT
bjos-8676163	127	3	the	the	DET
bjos-8676163	127	4	presence	presence	NOUN
bjos-8676163	127	5	of	of	ADP
bjos-8676163	127	6	antimicrobials	antimicrobial	NOUN
bjos-8676163	127	7	in	in	ADP
bjos-8676163	127	8	biofilms	biofilm	NOUN
bjos-8676163	127	9	can	can	AUX
bjos-8676163	127	10	result	result	VERB
bjos-8676163	127	11	in	in	ADP
bjos-8676163	127	12	secondary	secondary	ADJ
bjos-8676163	127	13	effects18	effects18	NOUN
bjos-8676163	127	14	that	that	PRON
bjos-8676163	127	15	may	may	AUX
bjos-8676163	127	16	also	also	ADV
bjos-8676163	127	17	impact	impact	VERB
bjos-8676163	127	18	other	other	ADJ
bjos-8676163	127	19	evaluated	evaluated	ADJ
bjos-8676163	127	20	outcomes	outcome	NOUN
bjos-8676163	127	21	.	.	PUNCT
bjos-8676163	128	1	some	some	DET
bjos-8676163	128	2	limitations	limitation	NOUN
bjos-8676163	128	3	of	of	ADP
bjos-8676163	128	4	our	our	PRON
bjos-8676163	128	5	study	study	NOUN
bjos-8676163	128	6	should	should	AUX
bjos-8676163	128	7	be	be	AUX
bjos-8676163	128	8	highlighted	highlight	VERB
bjos-8676163	128	9	.	.	PUNCT
bjos-8676163	129	1	while	while	SCONJ
bjos-8676163	129	2	the	the	DET
bjos-8676163	129	3	oral	oral	ADJ
bjos-8676163	129	4	cavity	cavity	NOUN
bjos-8676163	129	5	hosts	host	VERB
bjos-8676163	129	6	hundreds	hundred	NOUN
bjos-8676163	129	7	of	of	ADP
bjos-8676163	129	8	different	different	ADJ
bjos-8676163	129	9	species20	species20	NOUN
bjos-8676163	129	10	,	,	PUNCT
bjos-8676163	129	11	our	our	PRON
bjos-8676163	129	12	study	study	NOUN
bjos-8676163	129	13	focused	focus	VERB
bjos-8676163	129	14	only	only	ADV
bjos-8676163	129	15	on	on	ADP
bjos-8676163	129	16	s.	s.	PROPN
bjos-8676163	129	17	mutans	mutans	PROPN
bjos-8676163	129	18	.	.	PUNCT
bjos-8676163	130	1	however	however	ADV
bjos-8676163	130	2	,	,	PUNCT
bjos-8676163	130	3	s.	s.	PROPN
bjos-8676163	130	4	mutans	mutans	PROPN
bjos-8676163	130	5	is	be	AUX
bjos-8676163	130	6	a	a	DET
bjos-8676163	130	7	relevant	relevant	ADJ
bjos-8676163	130	8	species	specie	NOUN
bjos-8676163	130	9	due	due	ADP
bjos-8676163	130	10	to	to	ADP
bjos-8676163	130	11	its	its	PRON
bjos-8676163	130	12	ability	ability	NOUN
bjos-8676163	130	13	to	to	PART
bjos-8676163	130	14	produce	produce	VERB
bjos-8676163	130	15	an	an	DET
bjos-8676163	130	16	eps	eps	ADJ
bjos-8676163	130	17	-	-	PUNCT
bjos-8676163	130	18	rich	rich	ADJ
bjos-8676163	130	19	matrix	matrix	NOUN
bjos-8676163	130	20	and	and	CCONJ
bjos-8676163	130	21	its	its	PRON
bjos-8676163	130	22	association	association	NOUN
bjos-8676163	130	23	with	with	ADP
bjos-8676163	130	24	biofilms	biofilm	NOUN
bjos-8676163	130	25	,	,	PUNCT
bjos-8676163	130	26	which	which	PRON
bjos-8676163	130	27	contribute	contribute	VERB
bjos-8676163	130	28	to	to	ADP
bjos-8676163	130	29	dental	dental	ADJ
bjos-8676163	130	30	caries21	caries21	PROPN
bjos-8676163	130	31	-	-	PUNCT
bjos-8676163	130	32	23	23	NUM
bjos-8676163	130	33	.	.	PUNCT
bjos-8676163	131	1	since	since	SCONJ
bjos-8676163	131	2	eps	eps	PROPN
bjos-8676163	131	3	is	be	AUX
bjos-8676163	131	4	the	the	DET
bjos-8676163	131	5	target	target	NOUN
bjos-8676163	131	6	substrate	substrate	NOUN
bjos-8676163	131	7	for	for	ADP
bjos-8676163	131	8	dextranases	dextranase	NOUN
bjos-8676163	131	9	and	and	CCONJ
bjos-8676163	131	10	mutanases	mutanase	NOUN
bjos-8676163	131	11	,	,	PUNCT
bjos-8676163	131	12	the	the	DET
bjos-8676163	131	13	use	use	NOUN
bjos-8676163	131	14	of	of	ADP
bjos-8676163	131	15	this	this	DET
bjos-8676163	131	16	microorganism	microorganism	NOUN
bjos-8676163	131	17	was	be	AUX
bjos-8676163	131	18	appropriate	appropriate	ADJ
bjos-8676163	131	19	.	.	PUNCT
bjos-8676163	132	1	regarding	regard	VERB
bjos-8676163	132	2	the	the	DET
bjos-8676163	132	3	impact	impact	NOUN
bjos-8676163	132	4	on	on	ADP
bjos-8676163	132	5	other	other	ADJ
bjos-8676163	132	6	bacterial	bacterial	ADJ
bjos-8676163	132	7	species	specie	NOUN
bjos-8676163	132	8	,	,	PUNCT
bjos-8676163	132	9	rikvold	rikvold	VERB
bjos-8676163	132	10	et	et	PROPN
bjos-8676163	132	11	al.16	al.16	PROPN
bjos-8676163	132	12	(	(	PUNCT
bjos-8676163	132	13	2024	2024	NUM
bjos-8676163	132	14	)	)	PUNCT
bjos-8676163	132	15	did	do	AUX
bjos-8676163	132	16	not	not	PART
bjos-8676163	132	17	observe	observe	VERB
bjos-8676163	132	18	any	any	DET
bjos-8676163	132	19	antimicrobial	antimicrobial	ADJ
bjos-8676163	132	20	effects	effect	NOUN
bjos-8676163	132	21	.	.	PUNCT
bjos-8676163	133	1	therefore	therefore	ADV
bjos-8676163	133	2	,	,	PUNCT
bjos-8676163	133	3	studies	study	NOUN
bjos-8676163	133	4	evaluating	evaluate	VERB
bjos-8676163	133	5	commercially	commercially	ADV
bjos-8676163	133	6	available	available	ADJ
bjos-8676163	133	7	enzymes	enzyme	NOUN
bjos-8676163	133	8	aimed	aim	VERB
bjos-8676163	133	9	at	at	ADP
bjos-8676163	133	10	degrading	degrade	VERB
bjos-8676163	133	11	components	component	NOUN
bjos-8676163	133	12	of	of	ADP
bjos-8676163	133	13	the	the	DET
bjos-8676163	133	14	biofilm	biofilm	NOUN
bjos-8676163	133	15	matrix	matrix	NOUN
bjos-8676163	133	16	must	must	AUX
bjos-8676163	133	17	include	include	VERB
bjos-8676163	133	18	bacterial	bacterial	ADJ
bjos-8676163	133	19	viability	viability	NOUN
bjos-8676163	133	20	controls	control	NOUN
bjos-8676163	133	21	,	,	PUNCT
bjos-8676163	133	22	as	as	SCONJ
bjos-8676163	133	23	contaminants	contaminant	NOUN
bjos-8676163	133	24	within	within	ADP
bjos-8676163	133	25	the	the	DET
bjos-8676163	133	26	contents	content	NOUN
bjos-8676163	133	27	may	may	AUX
bjos-8676163	133	28	interfere	interfere	VERB
bjos-8676163	133	29	with	with	ADP
bjos-8676163	133	30	bacterial	bacterial	ADJ
bjos-8676163	133	31	growth	growth	NOUN
bjos-8676163	133	32	or	or	CCONJ
bjos-8676163	133	33	metabolism	metabolism	NOUN
bjos-8676163	133	34	.	.	PUNCT
bjos-8676163	134	1	in	in	ADP
bjos-8676163	134	2	addition	addition	NOUN
bjos-8676163	134	3	,	,	PUNCT
bjos-8676163	134	4	the	the	DET
bjos-8676163	134	5	inhibitory	inhibitory	ADJ
bjos-8676163	134	6	effects	effect	NOUN
bjos-8676163	134	7	of	of	ADP
bjos-8676163	134	8	the	the	DET
bjos-8676163	134	9	commercial	commercial	ADJ
bjos-8676163	134	10	dextranase	dextranase	NOUN
bjos-8676163	134	11	are	be	AUX
bjos-8676163	134	12	not	not	PART
bjos-8676163	134	13	clear	clear	ADJ
bjos-8676163	134	14	and	and	CCONJ
bjos-8676163	134	15	require	require	VERB
bjos-8676163	134	16	further	further	ADJ
bjos-8676163	134	17	investigation	investigation	NOUN
bjos-8676163	134	18	.	.	PUNCT
bjos-8676163	135	1	in	in	ADP
bjos-8676163	135	2	conclusion	conclusion	NOUN
bjos-8676163	135	3	,	,	PUNCT
bjos-8676163	135	4	the	the	DET
bjos-8676163	135	5	absence	absence	NOUN
bjos-8676163	135	6	of	of	ADP
bjos-8676163	135	7	inhibitory	inhibitory	ADJ
bjos-8676163	135	8	effects	effect	NOUN
bjos-8676163	135	9	on	on	ADP
bjos-8676163	135	10	s.	s.	PROPN
bjos-8676163	135	11	mutans	mutans	PROPN
bjos-8676163	135	12	growth	growth	NOUN
bjos-8676163	135	13	by	by	ADP
bjos-8676163	135	14	the	the	DET
bjos-8676163	135	15	newly	newly	ADV
bjos-8676163	135	16	discovered	discover	VERB
bjos-8676163	135	17	and	and	CCONJ
bjos-8676163	135	18	characterized	characterize	VERB
bjos-8676163	135	19	enzymes	enzyme	NOUN
bjos-8676163	135	20	emphasizes	emphasize	VERB
bjos-8676163	135	21	their	their	PRON
bjos-8676163	135	22	potential	potential	NOUN
bjos-8676163	135	23	for	for	ADP
bjos-8676163	135	24	biofilm	biofilm	NOUN
bjos-8676163	135	25	control	control	NOUN
bjos-8676163	135	26	while	while	SCONJ
bjos-8676163	135	27	preserving	preserve	VERB
bjos-8676163	135	28	the	the	DET
bjos-8676163	135	29	delicate	delicate	ADJ
bjos-8676163	135	30	balance	balance	NOUN
bjos-8676163	135	31	of	of	ADP
bjos-8676163	135	32	the	the	DET
bjos-8676163	135	33	oral	oral	ADJ
bjos-8676163	135	34	microbiota	microbiota	NOUN
bjos-8676163	135	35	and	and	CCONJ
bjos-8676163	135	36	mitigating	mitigate	VERB
bjos-8676163	135	37	the	the	DET
bjos-8676163	135	38	emergence	emergence	NOUN
bjos-8676163	135	39	of	of	ADP
bjos-8676163	135	40	resistance	resistance	NOUN
bjos-8676163	135	41	.	.	PUNCT
bjos-8676163	136	1	in	in	ADP
bjos-8676163	136	2	addition	addition	NOUN
bjos-8676163	136	3	,	,	PUNCT
bjos-8676163	136	4	this	this	DET
bjos-8676163	136	5	study	study	NOUN
bjos-8676163	136	6	highlights	highlight	VERB
bjos-8676163	136	7	the	the	DET
bjos-8676163	136	8	potential	potential	NOUN
bjos-8676163	136	9	of	of	ADP
bjos-8676163	136	10	biofilm	biofilm	NOUN
bjos-8676163	136	11	reduction	reduction	NOUN
bjos-8676163	136	12	previously	previously	ADV
bjos-8676163	136	13	demonstrated	demonstrate	VERB
bjos-8676163	136	14	by	by	ADP
bjos-8676163	136	15	our	our	PRON
bjos-8676163	136	16	group	group	NOUN
bjos-8676163	136	17	to	to	PART
bjos-8676163	136	18	be	be	AUX
bjos-8676163	136	19	solely	solely	ADV
bjos-8676163	136	20	attributable	attributable	ADJ
bjos-8676163	136	21	to	to	ADP
bjos-8676163	136	22	the	the	DET
bjos-8676163	136	23	enzymatic	enzymatic	ADJ
bjos-8676163	136	24	specific	specific	ADJ
bjos-8676163	136	25	action	action	NOUN
bjos-8676163	136	26	on	on	ADP
bjos-8676163	136	27	the	the	DET
bjos-8676163	136	28	eps	eps	NOUN
bjos-8676163	136	29	substrate	substrate	NOUN
bjos-8676163	136	30	.	.	PUNCT
bjos-8676163	137	1	furthermore	furthermore	ADV
bjos-8676163	137	2	,	,	PUNCT
bjos-8676163	137	3	it	it	PRON
bjos-8676163	137	4	is	be	AUX
bjos-8676163	137	5	crucial	crucial	ADJ
bjos-8676163	137	6	to	to	PART
bjos-8676163	137	7	further	far	ADV
bjos-8676163	137	8	investigate	investigate	VERB
bjos-8676163	137	9	the	the	DET
bjos-8676163	137	10	underlying	underlie	VERB
bjos-8676163	137	11	mechanisms	mechanism	NOUN
bjos-8676163	137	12	responsible	responsible	ADJ
bjos-8676163	137	13	for	for	ADP
bjos-8676163	137	14	the	the	DET
bjos-8676163	137	15	observed	observe	VERB
bjos-8676163	137	16	inhibitory	inhibitory	ADJ
bjos-8676163	137	17	effects	effect	NOUN
bjos-8676163	137	18	of	of	ADP
bjos-8676163	137	19	the	the	DET
bjos-8676163	137	20	commercial	commercial	ADJ
bjos-8676163	137	21	dextranase	dextranase	NOUN
bjos-8676163	137	22	,	,	PUNCT
bjos-8676163	137	23	as	as	SCONJ
bjos-8676163	137	24	it	it	PRON
bjos-8676163	137	25	is	be	AUX
bjos-8676163	137	26	commonly	commonly	ADV
bjos-8676163	137	27	employed	employ	VERB
bjos-8676163	137	28	in	in	ADP
bjos-8676163	137	29	research	research	NOUN
bjos-8676163	137	30	to	to	PART
bjos-8676163	137	31	evaluate	evaluate	VERB
bjos-8676163	137	32	anti	anti	ADJ
bjos-8676163	137	33	-	-	ADJ
bjos-8676163	137	34	biofilm	biofilm	ADJ
bjos-8676163	137	35	properties	property	NOUN
bjos-8676163	137	36	.	.	PUNCT
bjos-8676163	138	1	additionally	additionally	ADV
bjos-8676163	138	2	,	,	PUNCT
bjos-8676163	138	3	future	future	ADJ
bjos-8676163	138	4	research	research	NOUN
bjos-8676163	138	5	should	should	AUX
bjos-8676163	138	6	explore	explore	VERB
bjos-8676163	138	7	the	the	DET
bjos-8676163	138	8	broader	broad	ADJ
bjos-8676163	138	9	applications	application	NOUN
bjos-8676163	138	10	of	of	ADP
bjos-8676163	138	11	the	the	DET
bjos-8676163	138	12	newly	newly	ADV
bjos-8676163	138	13	discovered	discover	VERB
bjos-8676163	138	14	enzymes	enzyme	NOUN
bjos-8676163	138	15	to	to	PART
bjos-8676163	138	16	harness	harness	VERB
bjos-8676163	138	17	their	their	PRON
bjos-8676163	138	18	full	full	ADJ
bjos-8676163	138	19	potential	potential	NOUN
bjos-8676163	138	20	in	in	ADP
bjos-8676163	138	21	oral	oral	ADJ
bjos-8676163	138	22	health	health	NOUN
bjos-8676163	138	23	interventions	intervention	NOUN
bjos-8676163	138	24	.	.	PUNCT
bjos-8676163	139	1	declarations	declaration	NOUN
bjos-8676163	139	2	acknowledgements	acknowledgement	VERB
bjos-8676163	139	3	the	the	DET
bjos-8676163	139	4	authors	author	NOUN
bjos-8676163	139	5	are	be	AUX
bjos-8676163	139	6	thankful	thankful	ADJ
bjos-8676163	139	7	to	to	ADP
bjos-8676163	139	8	the	the	DET
bjos-8676163	139	9	institute	institute	NOUN
bjos-8676163	139	10	of	of	ADP
bjos-8676163	139	11	oral	oral	ADJ
bjos-8676163	139	12	biology	biology	NOUN
bjos-8676163	139	13	at	at	ADP
bjos-8676163	139	14	the	the	DET
bjos-8676163	139	15	university	university	PROPN
bjos-8676163	139	16	of	of	ADP
bjos-8676163	139	17	oslo	oslo	PROPN
bjos-8676163	139	18	,	,	PUNCT
bjos-8676163	139	19	the	the	DET
bjos-8676163	139	20	institute	institute	PROPN
bjos-8676163	139	21	of	of	ADP
bjos-8676163	139	22	physics	physics	PROPN
bjos-8676163	139	23	of	of	ADP
bjos-8676163	139	24	são	são	PROPN
bjos-8676163	139	25	carlos	carlos	PROPN
bjos-8676163	139	26	at	at	ADP
bjos-8676163	139	27	usp	usp	PROPN
bjos-8676163	139	28	,	,	PUNCT
bjos-8676163	139	29	and	and	CCONJ
bjos-8676163	139	30	the	the	DET
bjos-8676163	139	31	laboratory	laboratory	NOUN
bjos-8676163	139	32	of	of	ADP
bjos-8676163	139	33	biochemistry	biochemistry	NOUN
bjos-8676163	139	34	at	at	ADP
bjos-8676163	139	35	fop	fop	ADJ
bjos-8676163	139	36	-	-	ADJ
bjos-8676163	139	37	unicamp	unicamp	NOUN
bjos-8676163	139	38	for	for	ADP
bjos-8676163	139	39	providing	provide	VERB
bjos-8676163	139	40	the	the	DET
bjos-8676163	139	41	necessary	necessary	ADJ
bjos-8676163	139	42	facilities	facility	NOUN
bjos-8676163	139	43	to	to	PART
bjos-8676163	139	44	conduct	conduct	VERB
bjos-8676163	139	45	the	the	DET
bjos-8676163	139	46	analyses	analysis	NOUN
bjos-8676163	139	47	performed	perform	VERB
bjos-8676163	139	48	in	in	ADP
bjos-8676163	139	49	this	this	DET
bjos-8676163	139	50	study	study	NOUN
bjos-8676163	139	51	.	.	PUNCT
bjos-8676163	140	1	mateus	mateus	PROPN
bjos-8676163	140	2	xavier	xavier	PROPN
bjos-8676163	140	3	de	de	PROPN
bjos-8676163	140	4	queiroz	queiroz	ADV
bjos-8676163	140	5	is	be	AUX
bjos-8676163	140	6	a	a	DET
bjos-8676163	140	7	recipient	recipient	NOUN
bjos-8676163	140	8	of	of	ADP
bjos-8676163	140	9	phd	phd	NOUN
bjos-8676163	140	10	and	and	CCONJ
bjos-8676163	140	11	print	print	NOUN
bjos-8676163	140	12	scholarships	scholarship	NOUN
bjos-8676163	140	13	from	from	ADP
bjos-8676163	140	14	coordenação	coordenação	PROPN
bjos-8676163	140	15	de	de	PROPN
bjos-8676163	140	16	aperfeiçoamento	aperfeiçoamento	PROPN
bjos-8676163	140	17	de	de	X
bjos-8676163	140	18	pessoal	pessoal	PROPN
bjos-8676163	140	19	de	de	PROPN
bjos-8676163	140	20	nível	nível	PROPN
bjos-8676163	140	21	superior	superior	ADJ
bjos-8676163	140	22	(	(	PUNCT
bjos-8676163	140	23	capes	cape	NOUN
bjos-8676163	140	24	)	)	PUNCT
bjos-8676163	140	25	,	,	PUNCT
bjos-8676163	140	26	grants	grant	VERB
bjos-8676163	140	27	88887.800941/2023	88887.800941/2023	NOUN
bjos-8676163	140	28	-	-	SYM
bjos-8676163	140	29	00	00	NUM
bjos-8676163	140	30	and	and	CCONJ
bjos-8676163	140	31	88887.682625/2022	88887.682625/2022	PROPN
bjos-8676163	140	32	-	-	PUNCT
bjos-8676163	140	33	00	00	NUM
bjos-8676163	140	34	.	.	PUNCT
bjos-8676163	141	1	this	this	DET
bjos-8676163	141	2	study	study	NOUN
bjos-8676163	141	3	was	be	AUX
bjos-8676163	141	4	supported	support	VERB
bjos-8676163	141	5	by	by	ADP
bjos-8676163	141	6	capes	cape	NOUN
bjos-8676163	141	7	,	,	PUNCT
bjos-8676163	141	8	grant	grant	NOUN
bjos-8676163	141	9	001	001	NUM
bjos-8676163	141	10	;	;	PUNCT
bjos-8676163	141	11	by	by	ADP
bjos-8676163	141	12	fundo	fundo	PROPN
bjos-8676163	141	13	de	de	PROPN
bjos-8676163	141	14	apoio	apoio	PROPN
bjos-8676163	141	15	ao	ao	PROPN
bjos-8676163	141	16	ensino	ensino	PROPN
bjos-8676163	141	17	,	,	PUNCT
bjos-8676163	141	18	pesquisa	pesquisa	PROPN
bjos-8676163	141	19	e	e	NOUN
bjos-8676163	141	20	extensão	extensão	NOUN
bjos-8676163	141	21	(	(	PUNCT
bjos-8676163	141	22	faepex	faepex	PROPN
bjos-8676163	141	23	)	)	PUNCT
bjos-8676163	141	24	,	,	PUNCT
bjos-8676163	141	25	grant	grant	VERB
bjos-8676163	141	26	2501/23	2501/23	NUM
bjos-8676163	141	27	;	;	PUNCT
bjos-8676163	141	28	by	by	ADP
bjos-8676163	141	29	fundação	fundação	PROPN
bjos-8676163	141	30	de	de	X
bjos-8676163	141	31	amparo	amparo	PROPN
bjos-8676163	141	32	à	à	X
bjos-8676163	141	33	pesquisa	pesquisa	PROPN
bjos-8676163	141	34	do	do	AUX
bjos-8676163	141	35	estado	estado	PROPN
bjos-8676163	141	36	de	de	PROPN
bjos-8676163	141	37	são	são	PROPN
bjos-8676163	141	38	paulo	paulo	PROPN
bjos-8676163	141	39	(	(	PUNCT
bjos-8676163	141	40	fapesp	fapesp	NOUN
bjos-8676163	141	41	)	)	PUNCT
bjos-8676163	141	42	,	,	PUNCT
bjos-8676163	141	43	grants	grant	VERB
bjos-8676163	141	44	2020/15092	2020/15092	NUM
bjos-8676163	141	45	-	-	SYM
bjos-8676163	141	46	1	1	NUM
bjos-8676163	141	47	,	,	PUNCT
bjos-8676163	141	48	2021/08780	2021/08780	NUM
bjos-8676163	141	49	-	-	SYM
bjos-8676163	141	50	1	1	NUM
bjos-8676163	141	51	,	,	PUNCT
bjos-8676163	141	52	and	and	CCONJ
bjos-8676163	141	53	2023/07897	2023/07897	NUM
bjos-8676163	141	54	-	-	SYM
bjos-8676163	141	55	8	8	NUM
bjos-8676163	141	56	;	;	PUNCT
bjos-8676163	141	57	by	by	ADP
bjos-8676163	141	58	conselho	conselho	NOUN
bjos-8676163	141	59	nacional	nacional	PROPN
bjos-8676163	141	60	de	de	X
bjos-8676163	141	61	desenvolvimento	desenvolvimento	PROPN
bjos-8676163	141	62	científico	científico	PROPN
bjos-8676163	141	63	e	e	NOUN
bjos-8676163	141	64	tecnológico	tecnológico	PROPN
bjos-8676163	141	65	(	(	PUNCT
bjos-8676163	141	66	cnpq	cnpq	NOUN
bjos-8676163	141	67	)	)	PUNCT
bjos-8676163	141	68	,	,	PUNCT
bjos-8676163	141	69	grants	grant	VERB
bjos-8676163	141	70	306852/2021	306852/2021	NUM
bjos-8676163	141	71	-	-	SYM
bjos-8676163	141	72	7	7	NUM
bjos-8676163	141	73	and	and	CCONJ
bjos-8676163	141	74	440180/2022	440180/2022	NUM
bjos-8676163	141	75	-	-	SYM
bjos-8676163	141	76	8	8	NUM
bjos-8676163	141	77	;	;	PUNCT
bjos-8676163	141	78	and	and	CCONJ
bjos-8676163	141	79	by	by	ADP
bjos-8676163	141	80	research	research	NOUN
bjos-8676163	141	81	council	council	PROPN
bjos-8676163	141	82	of	of	ADP
bjos-8676163	141	83	norway	norway	PROPN
bjos-8676163	141	84	(	(	PUNCT
bjos-8676163	141	85	rcn	rcn	PROPN
bjos-8676163	141	86	)	)	PUNCT
bjos-8676163	141	87	,	,	PUNCT
bjos-8676163	141	88	grants	grant	VERB
bjos-8676163	141	89	274867	274867	NUM
bjos-8676163	141	90	and	and	CCONJ
bjos-8676163	141	91	322375	322375	NUM
bjos-8676163	141	92	.	.	PUNCT
bjos-8676163	142	1	9	9	NUM
bjos-8676163	142	2	queiroz	queiroz	ADV
bjos-8676163	142	3	et	et	PROPN
bjos-8676163	142	4	al	al	PROPN
bjos-8676163	142	5	.	.	PROPN
bjos-8676163	142	6	braz	braz	PROPN
bjos-8676163	142	7	j	j	PROPN
bjos-8676163	142	8	oral	oral	PROPN
bjos-8676163	142	9	sci	sci	PROPN
bjos-8676163	142	10	.	.	PUNCT
bjos-8676163	143	1	2024;23	2024;23	NUM
bjos-8676163	143	2	:	:	PUNCT
bjos-8676163	143	3	e246163	e246163	NUM
bjos-8676163	143	4	conflict	conflict	NOUN
bjos-8676163	143	5	of	of	ADP
bjos-8676163	143	6	interest	interest	NOUN
bjos-8676163	143	7	the	the	DET
bjos-8676163	143	8	authors	author	NOUN
bjos-8676163	143	9	have	have	VERB
bjos-8676163	143	10	no	no	DET
bjos-8676163	143	11	conflict	conflict	NOUN
bjos-8676163	143	12	of	of	ADP
bjos-8676163	143	13	interest	interest	NOUN
bjos-8676163	143	14	to	to	PART
bjos-8676163	143	15	disclose	disclose	VERB
bjos-8676163	143	16	.	.	PUNCT
bjos-8676163	144	1	data	datum	NOUN
bjos-8676163	144	2	availability	availability	NOUN
bjos-8676163	144	3	datasets	dataset	NOUN
bjos-8676163	144	4	related	relate	VERB
bjos-8676163	144	5	to	to	ADP
bjos-8676163	144	6	this	this	DET
bjos-8676163	144	7	article	article	NOUN
bjos-8676163	144	8	will	will	AUX
bjos-8676163	144	9	be	be	AUX
bjos-8676163	144	10	available	available	ADJ
bjos-8676163	144	11	to	to	ADP
bjos-8676163	144	12	the	the	DET
bjos-8676163	144	13	corresponding	corresponding	ADJ
bjos-8676163	144	14	author	author	NOUN
bjos-8676163	144	15	upon	upon	SCONJ
bjos-8676163	144	16	request	request	NOUN
bjos-8676163	144	17	.	.	PUNCT
bjos-8676163	145	1	author	author	NOUN
bjos-8676163	145	2	contribution	contribution	PROPN
bjos-8676163	145	3	mateus	mateus	PROPN
bjos-8676163	145	4	xavier	xavier	PROPN
bjos-8676163	145	5	de	de	PROPN
bjos-8676163	145	6	queiroz	queiroz	ADV
bjos-8676163	145	7	:	:	PUNCT
bjos-8676163	145	8	study	study	NOUN
bjos-8676163	145	9	conception	conception	NOUN
bjos-8676163	145	10	and	and	CCONJ
bjos-8676163	145	11	design	design	NOUN
bjos-8676163	145	12	,	,	PUNCT
bjos-8676163	145	13	experimental	experimental	ADJ
bjos-8676163	145	14	work	work	NOUN
bjos-8676163	145	15	,	,	PUNCT
bjos-8676163	145	16	data	data	NOUN
bjos-8676163	145	17	acquisition	acquisition	NOUN
bjos-8676163	145	18	,	,	PUNCT
bjos-8676163	145	19	data	data	NOUN
bjos-8676163	145	20	acquisition	acquisition	NOUN
bjos-8676163	145	21	,	,	PUNCT
bjos-8676163	145	22	data	datum	NOUN
bjos-8676163	145	23	analyses	analysis	NOUN
bjos-8676163	145	24	,	,	PUNCT
bjos-8676163	145	25	writing	writing	NOUN
bjos-8676163	145	26	and	and	CCONJ
bjos-8676163	145	27	manuscript	manuscript	PROPN
bjos-8676163	145	28	review	review	PROPN
bjos-8676163	145	29	.	.	PUNCT
bjos-8676163	146	1	pedro	pedro	PROPN
bjos-8676163	146	2	ricardo	ricardo	PROPN
bjos-8676163	146	3	viera	viera	PROPN
bjos-8676163	146	4	hamann	hamann	PROPN
bjos-8676163	146	5	:	:	PUNCT
bjos-8676163	146	6	experimental	experimental	ADJ
bjos-8676163	146	7	work	work	NOUN
bjos-8676163	146	8	,	,	PUNCT
bjos-8676163	146	9	data	data	NOUN
bjos-8676163	146	10	acquisition	acquisition	NOUN
bjos-8676163	146	11	.	.	PUNCT
bjos-8676163	147	1	heidi	heidi	PROPN
bjos-8676163	147	2	aarø	aarø	PROPN
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bjos-8676163	147	4	:	:	PUNCT
bjos-8676163	147	5	experimental	experimental	ADJ
bjos-8676163	147	6	work	work	NOUN
bjos-8676163	147	7	,	,	PUNCT
bjos-8676163	147	8	data	data	NOUN
bjos-8676163	147	9	acquisition	acquisition	NOUN
bjos-8676163	147	10	,	,	PUNCT
bjos-8676163	147	11	data	datum	NOUN
bjos-8676163	147	12	analyses	analysis	NOUN
bjos-8676163	147	13	.	.	PUNCT
bjos-8676163	148	1	igor	igor	PROPN
bjos-8676163	148	2	polikarpov	polikarpov	PROPN
bjos-8676163	148	3	:	:	PUNCT
bjos-8676163	148	4	study	study	NOUN
bjos-8676163	148	5	conception	conception	NOUN
bjos-8676163	148	6	and	and	CCONJ
bjos-8676163	148	7	design	design	NOUN
bjos-8676163	148	8	,	,	PUNCT
bjos-8676163	148	9	data	datum	NOUN
bjos-8676163	148	10	analyses	analysis	NOUN
bjos-8676163	148	11	,	,	PUNCT
bjos-8676163	148	12	writing	writing	NOUN
bjos-8676163	148	13	and	and	CCONJ
bjos-8676163	148	14	manuscript	manuscript	PROPN
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bjos-8676163	148	16	,	,	PUNCT
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bjos-8676163	148	18	acquisition	acquisition	NOUN
bjos-8676163	148	19	.	.	PUNCT
bjos-8676163	149	1	fernanda	fernanda	PROPN
bjos-8676163	149	2	cristina	cristina	PROPN
bjos-8676163	149	3	petersen	petersen	PROPN
bjos-8676163	149	4	:	:	PUNCT
bjos-8676163	149	5	study	study	NOUN
bjos-8676163	149	6	conception	conception	NOUN
bjos-8676163	149	7	and	and	CCONJ
bjos-8676163	149	8	design	design	NOUN
bjos-8676163	149	9	,	,	PUNCT
bjos-8676163	149	10	data	datum	NOUN
bjos-8676163	149	11	analyses	analysis	NOUN
bjos-8676163	149	12	,	,	PUNCT
bjos-8676163	149	13	writing	writing	NOUN
bjos-8676163	149	14	and	and	CCONJ
bjos-8676163	149	15	manuscript	manuscript	PROPN
bjos-8676163	149	16	review	review	PROPN
bjos-8676163	149	17	,	,	PUNCT
bjos-8676163	149	18	funding	funding	NOUN
bjos-8676163	149	19	acquisition	acquisition	NOUN
bjos-8676163	149	20	.	.	PUNCT
bjos-8676163	150	1	antonio	antonio	PROPN
bjos-8676163	150	2	pedro	pedro	PROPN
bjos-8676163	150	3	ricomini	ricomini	PROPN
bjos-8676163	150	4	filho	filho	PROPN
bjos-8676163	150	5	:	:	PUNCT
bjos-8676163	150	6	study	study	NOUN
bjos-8676163	150	7	conception	conception	NOUN
bjos-8676163	150	8	and	and	CCONJ
bjos-8676163	150	9	design	design	NOUN
bjos-8676163	150	10	,	,	PUNCT
bjos-8676163	150	11	data	datum	NOUN
bjos-8676163	150	12	analyses	analysis	NOUN
bjos-8676163	150	13	,	,	PUNCT
bjos-8676163	150	14	writing	writing	NOUN
bjos-8676163	150	15	and	and	CCONJ
bjos-8676163	150	16	manuscript	manuscript	PROPN
bjos-8676163	150	17	review	review	PROPN
bjos-8676163	150	18	,	,	PUNCT
bjos-8676163	150	19	funding	funding	NOUN
bjos-8676163	150	20	acquisition	acquisition	NOUN
bjos-8676163	150	21	.	.	PUNCT
bjos-8676163	151	1	all	all	DET
bjos-8676163	151	2	authors	author	NOUN
bjos-8676163	151	3	reviewed	review	VERB
bjos-8676163	151	4	the	the	DET
bjos-8676163	151	5	final	final	ADJ
bjos-8676163	151	6	version	version	NOUN
bjos-8676163	151	7	of	of	ADP
bjos-8676163	151	8	the	the	DET
bjos-8676163	151	9	manuscript	manuscript	NOUN
bjos-8676163	151	10	.	.	PUNCT
bjos-8676163	152	1	references	reference	NOUN
bjos-8676163	152	2	1	1	NUM
bjos-8676163	152	3	.	.	PUNCT
bjos-8676163	153	1	thallinger	thallinger	PROPN
bjos-8676163	153	2	b	b	PROPN
bjos-8676163	153	3	,	,	PUNCT
bjos-8676163	153	4	prasetyo	prasetyo	NOUN
bjos-8676163	153	5	en	en	X
bjos-8676163	153	6	,	,	PUNCT
bjos-8676163	153	7	nyanhongo	nyanhongo	NOUN
bjos-8676163	153	8	gs	gs	NOUN
bjos-8676163	153	9	,	,	PUNCT
bjos-8676163	153	10	guebitz	guebitz	PROPN
bjos-8676163	153	11	gm	gm	PROPN
bjos-8676163	153	12	.	.	PUNCT
bjos-8676163	154	1	antimicrobial	antimicrobial	ADJ
bjos-8676163	154	2	enzymes	enzyme	NOUN
bjos-8676163	154	3	:	:	PUNCT
bjos-8676163	154	4	an	an	DET
bjos-8676163	154	5	emerging	emerge	VERB
bjos-8676163	154	6	strategy	strategy	NOUN
bjos-8676163	154	7	to	to	PART
bjos-8676163	154	8	fight	fight	VERB
bjos-8676163	154	9	microbes	microbe	NOUN
bjos-8676163	154	10	and	and	CCONJ
bjos-8676163	154	11	microbial	microbial	ADJ
bjos-8676163	154	12	biofilms	biofilm	NOUN
bjos-8676163	154	13	.	.	PUNCT
bjos-8676163	155	1	biotechnol	biotechnol	PROPN
bjos-8676163	155	2	j.	j.	PROPN
bjos-8676163	155	3	2013	2013	PROPN
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bjos-8676163	155	5	-	-	PUNCT
bjos-8676163	155	6	109	109	NUM
bjos-8676163	155	7	.	.	PUNCT
bjos-8676163	156	1	doi	doi	NOUN
bjos-8676163	156	2	:	:	PUNCT
bjos-8676163	156	3	10.1002	10.1002	NUM
bjos-8676163	156	4	/	/	SYM
bjos-8676163	156	5	biot.201200313	biot.201200313	PROPN
bjos-8676163	156	6	.	.	NOUN
bjos-8676163	156	7	  	  	SPACE
bjos-8676163	156	8	2	2	NUM
bjos-8676163	156	9	.	.	PUNCT
bjos-8676163	156	10	bowen	bowen	PROPN
bjos-8676163	156	11	wh	wh	PROPN
bjos-8676163	156	12	,	,	PUNCT
bjos-8676163	156	13	koo	koo	PROPN
bjos-8676163	156	14	h.	h.	PROPN
bjos-8676163	156	15	biology	biology	NOUN
bjos-8676163	156	16	of	of	ADP
bjos-8676163	156	17	streptococcus	streptococcus	NOUN
bjos-8676163	156	18	mutans	mutan	NOUN
bjos-8676163	156	19	-	-	PUNCT
bjos-8676163	156	20	derived	derive	VERB
bjos-8676163	156	21	glucosyltransferases	glucosyltransferase	NOUN
bjos-8676163	156	22	:	:	PUNCT
bjos-8676163	156	23	role	role	NOUN
bjos-8676163	156	24	in	in	ADP
bjos-8676163	156	25	extracellular	extracellular	ADJ
bjos-8676163	156	26	matrix	matrix	NOUN
bjos-8676163	156	27	formation	formation	NOUN
bjos-8676163	156	28	of	of	ADP
bjos-8676163	156	29	cariogenic	cariogenic	ADJ
bjos-8676163	156	30	biofilms	biofilm	NOUN
bjos-8676163	156	31	.	.	PUNCT
bjos-8676163	157	1	caries	carie	NOUN
bjos-8676163	157	2	res	re	NOUN
bjos-8676163	157	3	.	.	PUNCT
bjos-8676163	158	1	2011;45(1):69	2011;45(1):69	NUM
bjos-8676163	158	2	-	-	SYM
bjos-8676163	158	3	86	86	NUM
bjos-8676163	158	4	.	.	PUNCT
bjos-8676163	159	1	doi	doi	NOUN
bjos-8676163	159	2	:	:	PUNCT
bjos-8676163	159	3	10.1159/000324598	10.1159/000324598	NUM
bjos-8676163	159	4	.	.	PUNCT
bjos-8676163	159	5	  	  	SPACE
bjos-8676163	160	1	3	3	X
bjos-8676163	160	2	.	.	PUNCT
bjos-8676163	160	3	pleszczyńska	pleszczyńska	PROPN
bjos-8676163	160	4	m	m	PROPN
bjos-8676163	160	5	,	,	PUNCT
bjos-8676163	160	6	wiater	wiater	NOUN
bjos-8676163	160	7	a	a	PRON
bjos-8676163	160	8	,	,	PUNCT
bjos-8676163	160	9	janczarek	janczarek	PROPN
bjos-8676163	160	10	m	m	PROPN
bjos-8676163	160	11	,	,	PUNCT
bjos-8676163	160	12	szczodrak	szczodrak	PROPN
bjos-8676163	160	13	j.	j.	PROPN
bjos-8676163	160	14	(	(	PUNCT
bjos-8676163	160	15	1→3)-α	1→3)-α	NUM
bjos-8676163	160	16	-	-	PUNCT
bjos-8676163	160	17	d	d	NOUN
bjos-8676163	160	18	-	-	PUNCT
bjos-8676163	160	19	glucan	glucan	NOUN
bjos-8676163	160	20	hydrolases	hydrolase	NOUN
bjos-8676163	160	21	in	in	ADP
bjos-8676163	160	22	dental	dental	ADJ
bjos-8676163	160	23	biofilm	biofilm	NOUN
bjos-8676163	160	24	prevention	prevention	NOUN
bjos-8676163	160	25	and	and	CCONJ
bjos-8676163	160	26	control	control	PROPN
bjos-8676163	160	27	:	:	PUNCT
bjos-8676163	160	28	a	a	DET
bjos-8676163	160	29	review	review	NOUN
bjos-8676163	160	30	.	.	PUNCT
bjos-8676163	161	1	int	int	NOUN
bjos-8676163	161	2	j	j	PROPN
bjos-8676163	161	3	biol	biol	PROPN
bjos-8676163	161	4	macromol	macromol	PROPN
bjos-8676163	161	5	.	.	PUNCT
bjos-8676163	162	1	2015	2015	NUM
bjos-8676163	162	2	aug;79:761	aug;79:761	ADJ
bjos-8676163	162	3	-	-	X
bjos-8676163	162	4	78	78	NUM
bjos-8676163	162	5	.	.	PUNCT
bjos-8676163	163	1	doi	doi	NOUN
bjos-8676163	163	2	:	:	PUNCT
bjos-8676163	163	3	10.1016	10.1016	NUM
bjos-8676163	163	4	/	/	SYM
bjos-8676163	163	5	j.ijbiomac.2015.05.052	j.ijbiomac.2015.05.052	PROPN
bjos-8676163	163	6	.	.	PROPN
bjos-8676163	164	1	4	4	X
bjos-8676163	164	2	.	.	X
bjos-8676163	165	1	ren	ren	PROPN
bjos-8676163	165	2	z	z	PROPN
bjos-8676163	165	3	,	,	PUNCT
bjos-8676163	165	4	kim	kim	PROPN
bjos-8676163	165	5	d	d	PROPN
bjos-8676163	165	6	,	,	PUNCT
bjos-8676163	165	7	paula	paula	PROPN
bjos-8676163	165	8	aj	aj	PROPN
bjos-8676163	165	9	,	,	PUNCT
bjos-8676163	165	10	hwang	hwang	PROPN
bjos-8676163	165	11	g	g	PROPN
bjos-8676163	165	12	,	,	PUNCT
bjos-8676163	165	13	liu	liu	PROPN
bjos-8676163	165	14	y	y	PROPN
bjos-8676163	165	15	,	,	PUNCT
bjos-8676163	165	16	li	li	PROPN
bjos-8676163	165	17	j	j	PROPN
bjos-8676163	165	18	,	,	PUNCT
bjos-8676163	165	19	et	et	PROPN
bjos-8676163	165	20	al	al	PROPN
bjos-8676163	165	21	.	.	PUNCT
bjos-8676163	165	22	dual	dual	ADV
bjos-8676163	165	23	-	-	PUNCT
bjos-8676163	165	24	targeting	target	VERB
bjos-8676163	165	25	approach	approach	NOUN
bjos-8676163	165	26	degrades	degrade	VERB
bjos-8676163	165	27	biofilm	biofilm	NOUN
bjos-8676163	165	28	matrix	matrix	NOUN
bjos-8676163	165	29	and	and	CCONJ
bjos-8676163	165	30	enhances	enhance	VERB
bjos-8676163	165	31	bacterial	bacterial	ADJ
bjos-8676163	165	32	killing	killing	NOUN
bjos-8676163	165	33	.	.	PUNCT
bjos-8676163	166	1	j	j	PROPN
bjos-8676163	166	2	dent	dent	NOUN
bjos-8676163	166	3	res	re	NOUN
bjos-8676163	166	4	.	.	PUNCT
bjos-8676163	167	1	2019	2019	NUM
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bjos-8676163	167	3	-	-	SYM
bjos-8676163	167	4	30	30	NUM
bjos-8676163	167	5	.	.	PUNCT
bjos-8676163	168	1	doi	doi	NOUN
bjos-8676163	168	2	:	:	PUNCT
bjos-8676163	168	3	10.1177/0022034518818480	10.1177/0022034518818480	NUM
bjos-8676163	168	4	.	.	NOUN
bjos-8676163	169	1	5	5	NUM
bjos-8676163	169	2	.	.	X
bjos-8676163	170	1	kim	kim	PROPN
bjos-8676163	170	2	d	d	PROPN
bjos-8676163	170	3	,	,	PUNCT
bjos-8676163	170	4	liu	liu	PROPN
bjos-8676163	170	5	y	y	PROPN
bjos-8676163	170	6	,	,	PUNCT
bjos-8676163	170	7	benhamou	benhamou	PROPN
bjos-8676163	170	8	ri	ri	PROPN
bjos-8676163	170	9	,	,	PUNCT
bjos-8676163	170	10	sanchez	sanchez	PROPN
bjos-8676163	170	11	h	h	PROPN
bjos-8676163	170	12	,	,	PUNCT
bjos-8676163	170	13	simón	simón	PROPN
bjos-8676163	170	14	-	-	PUNCT
bjos-8676163	170	15	soro	soro	PROPN
bjos-8676163	170	16	á	á	PROPN
bjos-8676163	170	17	,	,	PUNCT
bjos-8676163	170	18	li	li	PROPN
bjos-8676163	170	19	y	y	PROPN
bjos-8676163	170	20	,	,	PUNCT
bjos-8676163	170	21	et	et	PROPN
bjos-8676163	170	22	al	al	PROPN
bjos-8676163	170	23	.	.	PUNCT
bjos-8676163	171	1	bacterial	bacterial	ADJ
bjos-8676163	171	2	-	-	PUNCT
bjos-8676163	171	3	derived	derive	VERB
bjos-8676163	171	4	exopolysaccharides	exopolysaccharide	NOUN
bjos-8676163	171	5	enhance	enhance	VERB
bjos-8676163	171	6	antifungal	antifungal	ADJ
bjos-8676163	171	7	drug	drug	NOUN
bjos-8676163	171	8	tolerance	tolerance	NOUN
bjos-8676163	171	9	in	in	ADP
bjos-8676163	171	10	a	a	DET
bjos-8676163	171	11	cross	cross	ADJ
bjos-8676163	171	12	-	-	ADJ
bjos-8676163	171	13	kingdom	kingdom	ADJ
bjos-8676163	171	14	oral	oral	ADJ
bjos-8676163	171	15	biofilm	biofilm	NOUN
bjos-8676163	171	16	.	.	PUNCT
bjos-8676163	172	1	isme	isme	PROPN
bjos-8676163	172	2	j.	j.	PROPN
bjos-8676163	172	3	2018	2018	NUM
bjos-8676163	172	4	jun;12(6):1427	jun;12(6):1427	PROPN
bjos-8676163	172	5	-	-	PUNCT
bjos-8676163	172	6	42	42	NUM
bjos-8676163	172	7	.	.	PUNCT
bjos-8676163	173	1	doi	doi	NOUN
bjos-8676163	173	2	:	:	PUNCT
bjos-8676163	173	3	10.1038	10.1038	NUM
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bjos-8676163	173	5	s41396	s41396	NOUN
bjos-8676163	173	6	-	-	PUNCT
bjos-8676163	173	7	018	018	NUM
bjos-8676163	173	8	-	-	PUNCT
bjos-8676163	173	9	0113	0113	NUM
bjos-8676163	173	10	-	-	SYM
bjos-8676163	173	11	1	1	NUM
bjos-8676163	173	12	.	.	NOUN
bjos-8676163	173	13	6	6	NUM
bjos-8676163	173	14	.	.	X
bjos-8676163	174	1	liu	liu	PROPN
bjos-8676163	174	2	n	n	PROPN
bjos-8676163	174	3	,	,	PUNCT
bjos-8676163	174	4	li	li	PROPN
bjos-8676163	174	5	x	x	PROPN
bjos-8676163	174	6	,	,	PUNCT
bjos-8676163	174	7	wang	wang	PROPN
bjos-8676163	174	8	m	m	PROPN
bjos-8676163	174	9	,	,	PUNCT
bjos-8676163	174	10	zhang	zhang	PROPN
bjos-8676163	174	11	f	f	PROPN
bjos-8676163	174	12	,	,	PUNCT
bjos-8676163	174	13	wang	wang	PROPN
bjos-8676163	174	14	c	c	PROPN
bjos-8676163	174	15	,	,	PUNCT
bjos-8676163	174	16	zhang	zhang	PROPN
bjos-8676163	174	17	k	k	PROPN
bjos-8676163	174	18	,	,	PUNCT
bjos-8676163	174	19	et	et	PROPN
bjos-8676163	174	20	al	al	PROPN
bjos-8676163	174	21	.	.	PROPN
bjos-8676163	174	22	dexa70	dexa70	PROPN
bjos-8676163	174	23	,	,	PUNCT
bjos-8676163	174	24	the	the	DET
bjos-8676163	174	25	truncated	truncated	ADJ
bjos-8676163	174	26	form	form	NOUN
bjos-8676163	174	27	of	of	ADP
bjos-8676163	174	28	a	a	DET
bjos-8676163	174	29	self	self	NOUN
bjos-8676163	174	30	-	-	PUNCT
bjos-8676163	174	31	produced	produce	VERB
bjos-8676163	174	32	dextranase	dextranase	NOUN
bjos-8676163	174	33	,	,	PUNCT
bjos-8676163	174	34	effectively	effectively	ADV
bjos-8676163	174	35	disrupts	disrupt	VERB
bjos-8676163	174	36	 	 	SPACE
bjos-8676163	174	37	streptococcus	streptococcus	NOUN
bjos-8676163	174	38	mutans	mutan	NOUN
bjos-8676163	174	39	 	 	SPACE
bjos-8676163	174	40	biofilm	biofilm	NOUN
bjos-8676163	174	41	.	.	PUNCT
bjos-8676163	175	1	front	front	PROPN
bjos-8676163	175	2	microbiol	microbiol	PROPN
bjos-8676163	175	3	.	.	PUNCT
bjos-8676163	176	1	2021	2021	NUM
bjos-8676163	176	2	sep;12:737458	sep;12:737458	NOUN
bjos-8676163	176	3	.	.	PUNCT
bjos-8676163	177	1	doi	doi	NOUN
bjos-8676163	177	2	:	:	PUNCT
bjos-8676163	177	3	10.3389	10.3389	NUM
bjos-8676163	177	4	/	/	SYM
bjos-8676163	177	5	fmicb.2021.737458	fmicb.2021.737458	NOUN
bjos-8676163	177	6	.	.	PUNCT
bjos-8676163	178	1	7	7	X
bjos-8676163	178	2	.	.	X
bjos-8676163	178	3	juntarachot	juntarachot	PROPN
bjos-8676163	178	4	n	n	CCONJ
bjos-8676163	178	5	,	,	PUNCT
bjos-8676163	178	6	sirilun	sirilun	PROPN
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bjos-8676163	178	8	,	,	PUNCT
bjos-8676163	178	9	kantachote	kantachote	PROPN
bjos-8676163	178	10	d	d	PROPN
bjos-8676163	178	11	,	,	PUNCT
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bjos-8676163	178	14	,	,	PUNCT
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bjos-8676163	178	17	,	,	PUNCT
bjos-8676163	178	18	peerajan	peerajan	NOUN
bjos-8676163	178	19	s	s	PROPN
bjos-8676163	178	20	,	,	PUNCT
bjos-8676163	178	21	et	et	PROPN
bjos-8676163	178	22	al	al	PROPN
bjos-8676163	178	23	.	.	PROPN
bjos-8676163	178	24	antistreptococcus	antistreptococcus	NOUN
bjos-8676163	178	25	mutans	mutan	NOUN
bjos-8676163	178	26	and	and	CCONJ
bjos-8676163	178	27	anti	anti	ADJ
bjos-8676163	178	28	-	-	ADJ
bjos-8676163	178	29	biofilm	biofilm	ADJ
bjos-8676163	178	30	activities	activity	NOUN
bjos-8676163	178	31	of	of	ADP
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bjos-8676163	178	36	in	in	ADP
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bjos-8676163	178	39	for	for	ADP
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bjos-8676163	178	41	in	in	ADP
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bjos-8676163	178	43	.	.	PUNCT
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bjos-8676163	179	2	.	.	PUNCT
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bjos-8676163	181	10	.	.	PROPN
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bjos-8676163	181	15	.	.	PROPN
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bjos-8676163	181	20	.	.	PUNCT
bjos-8676163	182	1	2024;23	2024;23	NUM
bjos-8676163	182	2	:	:	PUNCT
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bjos-8676163	182	5	.	.	PUNCT
bjos-8676163	183	1	qiu	qiu	PROPN
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bjos-8676163	183	3	,	,	PUNCT
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bjos-8676163	184	2	,	,	PUNCT
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bjos-8676163	184	5	,	,	PUNCT
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bjos-8676163	184	8	,	,	PUNCT
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bjos-8676163	185	9	and	and	CCONJ
bjos-8676163	185	10	sodium	sodium	NOUN
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bjos-8676163	185	15	.	.	PUNCT
bjos-8676163	186	1	j	j	PROPN
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bjos-8676163	187	2	-	-	PUNCT
bjos-8676163	187	3	7	7	NUM
bjos-8676163	187	4	.	.	PUNCT
bjos-8676163	187	5	doi	doi	NOUN
bjos-8676163	187	6	:	:	PUNCT
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bjos-8676163	187	8	/	/	SYM
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bjos-8676163	187	10	.	.	PUNCT
bjos-8676163	188	1	9	9	X
bjos-8676163	188	2	.	.	X
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bjos-8676163	188	8	,	,	PUNCT
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bjos-8676163	188	11	,	,	PUNCT
bjos-8676163	188	12	lin	lin	PROPN
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bjos-8676163	188	14	,	,	PUNCT
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bjos-8676163	188	17	,	,	PUNCT
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bjos-8676163	188	19	s	s	PROPN
bjos-8676163	188	20	,	,	PUNCT
bjos-8676163	188	21	et	et	PROPN
bjos-8676163	188	22	al	al	PROPN
bjos-8676163	188	23	.	.	PROPN
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bjos-8676163	189	2	oral	oral	ADJ
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bjos-8676163	189	4	care	care	NOUN
bjos-8676163	189	5	:	:	PUNCT
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bjos-8676163	189	9	using	use	VERB
bjos-8676163	189	10	chloroplast	chloroplast	NOUN
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bjos-8676163	189	17	.	.	PUNCT
bjos-8676163	190	1	plant	plant	NOUN
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bjos-8676163	190	3	j.	j.	PROPN
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bjos-8676163	190	8	.	.	PUNCT
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bjos-8676163	190	14	.	.	NOUN
bjos-8676163	191	1	10	10	NUM
bjos-8676163	191	2	.	.	PUNCT
bjos-8676163	191	3	cortez	cortez	PROPN
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bjos-8676163	191	5	,	,	PUNCT
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bjos-8676163	191	7	queiroz	queiroz	ADV
bjos-8676163	191	8	mx	mx	PROPN
bjos-8676163	191	9	,	,	PUNCT
bjos-8676163	191	10	de	de	PROPN
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bjos-8676163	191	14	v	v	PROPN
bjos-8676163	191	15	,	,	PUNCT
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bjos-8676163	191	18	,	,	PUNCT
bjos-8676163	191	19	de	de	PROPN
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bjos-8676163	191	23	,	,	PUNCT
bjos-8676163	191	24	dabul	dabul	PROPN
bjos-8676163	191	25	ang	ang	PROPN
bjos-8676163	191	26	,	,	PUNCT
bjos-8676163	191	27	et	et	PROPN
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bjos-8676163	191	36	capnocytophaga	capnocytophaga	NOUN
bjos-8676163	191	37	ochracea	ochracea	NOUN
bjos-8676163	191	38	α-1,6	α-1,6	PROPN
bjos-8676163	191	39	glucanase	glucanase	PROPN
bjos-8676163	191	40	as	as	ADP
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bjos-8676163	191	43	for	for	ADP
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bjos-8676163	191	48	s.	s.	PROPN
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bjos-8676163	191	50	biofilms	biofilms	PROPN
bjos-8676163	191	51	.	.	PUNCT
bjos-8676163	192	1	world	world	PROPN
bjos-8676163	192	2	j	j	PROPN
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bjos-8676163	192	4	biotechnol	biotechnol	PROPN
bjos-8676163	192	5	.	.	PUNCT
bjos-8676163	193	1	2023	2023	NUM
bjos-8676163	193	2	oct;39(12):357	oct;39(12):357	PROPN
bjos-8676163	193	3	.	.	PUNCT
bjos-8676163	193	4	doi	doi	NOUN
bjos-8676163	193	5	:	:	PUNCT
bjos-8676163	193	6	10.1007	10.1007	NUM
bjos-8676163	193	7	/	/	SYM
bjos-8676163	193	8	s11274	s11274	ADJ
bjos-8676163	193	9	-	-	PUNCT
bjos-8676163	193	10	023	023	NUM
bjos-8676163	193	11	-	-	PUNCT
bjos-8676163	193	12	03804	03804	NUM
bjos-8676163	193	13	-	-	PUNCT
bjos-8676163	193	14	z.	z.	PROPN
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bjos-8676163	193	16	.	.	PUNCT
bjos-8676163	194	1	pozelli	pozelli	PROPN
bjos-8676163	194	2	macedo	macedo	PROPN
bjos-8676163	194	3	mj	mj	PROPN
bjos-8676163	194	4	,	,	PUNCT
bjos-8676163	194	5	xavier	xavier	PROPN
bjos-8676163	194	6	-	-	PUNCT
bjos-8676163	194	7	queiroz	queiroz	PROPN
bjos-8676163	194	8	m	m	PROPN
bjos-8676163	194	9	,	,	PUNCT
bjos-8676163	194	10	dabul	dabul	PROPN
bjos-8676163	194	11	ang	ang	PROPN
bjos-8676163	194	12	,	,	PUNCT
bjos-8676163	194	13	ricomini	ricomini	NOUN
bjos-8676163	194	14	-	-	ADJ
bjos-8676163	194	15	filho	filho	ADJ
bjos-8676163	194	16	ap	ap	PROPN
bjos-8676163	194	17	,	,	PUNCT
bjos-8676163	194	18	hamann	hamann	PROPN
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bjos-8676163	194	20	,	,	PUNCT
bjos-8676163	194	21	polikarpov	polikarpov	PROPN
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bjos-8676163	194	25	of	of	ADP
bjos-8676163	194	26	a	a	DET
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bjos-8676163	194	28	johnsoniae	johnsoniae	NOUN
bjos-8676163	194	29	dextranase	dextranase	NOUN
bjos-8676163	194	30	and	and	CCONJ
bjos-8676163	194	31	its	its	PRON
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bjos-8676163	194	33	potential	potential	NOUN
bjos-8676163	194	34	for	for	ADP
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bjos-8676163	194	36	mutans	mutan	NOUN
bjos-8676163	194	37	biofilm	biofilm	NOUN
bjos-8676163	194	38	degradation	degradation	NOUN
bjos-8676163	194	39	.	.	PUNCT
bjos-8676163	195	1	world	world	PROPN
bjos-8676163	195	2	j	j	PROPN
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bjos-8676163	195	4	biotechnol	biotechnol	PROPN
bjos-8676163	195	5	.	.	PUNCT
bjos-8676163	196	1	2024	2024	NUM
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bjos-8676163	196	3	.	.	PUNCT
bjos-8676163	197	1	doi	doi	NOUN
bjos-8676163	197	2	:	:	PUNCT
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bjos-8676163	197	4	/	/	SYM
bjos-8676163	197	5	s11274	s11274	NOUN
bjos-8676163	197	6	-	-	PUNCT
bjos-8676163	197	7	024	024	NUM
bjos-8676163	197	8	-	-	PUNCT
bjos-8676163	197	9	04014	04014	NUM
bjos-8676163	197	10	-	-	PUNCT
bjos-8676163	197	11	x.	x.	NOUN
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bjos-8676163	197	13	.	.	PUNCT
bjos-8676163	198	1	camilo	camilo	PROPN
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bjos-8676163	198	3	,	,	PUNCT
bjos-8676163	198	4	polikarpov	polikarpov	PROPN
bjos-8676163	198	5	i.	i.	PROPN
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bjos-8676163	198	7	-	-	PUNCT
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bjos-8676163	198	10	,	,	PUNCT
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bjos-8676163	198	16	hydrolases	hydrolase	NOUN
bjos-8676163	198	17	using	use	VERB
bjos-8676163	198	18	ligation	ligation	NOUN
bjos-8676163	198	19	-	-	PUNCT
bjos-8676163	198	20	independent	independent	ADJ
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bjos-8676163	198	22	(	(	PUNCT
bjos-8676163	198	23	lic	lic	PROPN
bjos-8676163	198	24	)	)	PUNCT
bjos-8676163	198	25	.	.	PUNCT
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bjos-8676163	199	4	.	.	PUNCT
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bjos-8676163	200	3	-	-	PUNCT
bjos-8676163	200	4	42	42	NUM
bjos-8676163	200	5	.	.	PUNCT
bjos-8676163	201	1	doi	doi	NOUN
bjos-8676163	201	2	:	:	PUNCT
bjos-8676163	201	3	10.1016	10.1016	NUM
bjos-8676163	201	4	/	/	SYM
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bjos-8676163	201	6	.	.	PUNCT
bjos-8676163	202	1	13	13	NUM
bjos-8676163	202	2	.	.	PUNCT
bjos-8676163	203	1	merritt	merritt	PROPN
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bjos-8676163	203	3	,	,	PUNCT
bjos-8676163	203	4	kreth	kreth	PROPN
bjos-8676163	203	5	j	j	PROPN
bjos-8676163	203	6	,	,	PUNCT
bjos-8676163	203	7	qi	qi	PROPN
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bjos-8676163	203	9	,	,	PUNCT
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bjos-8676163	203	12	,	,	PUNCT
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bjos-8676163	203	31	mutans	mutan	NOUN
bjos-8676163	203	32	cells	cell	NOUN
bjos-8676163	203	33	in	in	ADP
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bjos-8676163	203	38	.	.	PUNCT
bjos-8676163	204	1	j	j	PROPN
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bjos-8676163	204	4	.	.	PUNCT
bjos-8676163	205	1	2005	2005	NUM
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bjos-8676163	205	3	-	-	PUNCT
bjos-8676163	205	4	70	70	PROPN
bjos-8676163	205	5	.	.	PUNCT
bjos-8676163	206	1	doi	doi	NOUN
bjos-8676163	206	2	:	:	PUNCT
bjos-8676163	206	3	10.1016	10.1016	NUM
bjos-8676163	206	4	/	/	SYM
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bjos-8676163	206	6	.	.	PUNCT
bjos-8676163	207	1	14	14	NUM
bjos-8676163	207	2	.	.	PUNCT
bjos-8676163	208	1	dornelas	dornela	NOUN
bjos-8676163	208	2	-	-	PUNCT
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bjos-8676163	208	15	,	,	PUNCT
bjos-8676163	208	16	cury	cury	PROPN
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bjos-8676163	208	18	,	,	PUNCT
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bjos-8676163	209	3	impact	impact	NOUN
bjos-8676163	209	4	of	of	ADP
bjos-8676163	209	5	fluconazole	fluconazole	NOUN
bjos-8676163	209	6	on	on	ADP
bjos-8676163	209	7	oral	oral	ADJ
bjos-8676163	209	8	microbial	microbial	ADJ
bjos-8676163	209	9	communities	community	NOUN
bjos-8676163	209	10	,	,	PUNCT
bjos-8676163	209	11	bacterial	bacterial	ADJ
bjos-8676163	209	12	growth	growth	NOUN
bjos-8676163	209	13	,	,	PUNCT
bjos-8676163	209	14	and	and	CCONJ
bjos-8676163	209	15	biofilm	biofilm	NOUN
bjos-8676163	209	16	formation	formation	NOUN
bjos-8676163	209	17	.	.	PUNCT
bjos-8676163	210	1	antibiotics	antibiotic	NOUN
bjos-8676163	210	2	(	(	PUNCT
bjos-8676163	210	3	basel	basel	PROPN
bjos-8676163	210	4	)	)	PUNCT
bjos-8676163	210	5	.	.	PUNCT
bjos-8676163	211	1	2023	2023	NUM
bjos-8676163	211	2	sep;12(9):1433	sep;12(9):1433	PROPN
bjos-8676163	211	3	.	.	PUNCT
bjos-8676163	212	1	doi	doi	PROPN
bjos-8676163	212	2	:	:	PUNCT
bjos-8676163	212	3	10.3390	10.3390	NUM
bjos-8676163	212	4	/	/	SYM
bjos-8676163	212	5	antibiotics12091433	antibiotics12091433	PROPN
bjos-8676163	212	6	.	.	PUNCT
bjos-8676163	213	1	15	15	NUM
bjos-8676163	213	2	.	.	PUNCT
bjos-8676163	213	3	khan	khan	PROPN
bjos-8676163	213	4	r	r	PROPN
bjos-8676163	213	5	,	,	PUNCT
bjos-8676163	213	6	rukke	rukke	PROPN
bjos-8676163	213	7	hv	hv	PROPN
bjos-8676163	213	8	,	,	PUNCT
bjos-8676163	213	9	ricomini	ricomini	PROPN
bjos-8676163	213	10	filho	filho	PROPN
bjos-8676163	213	11	ap	ap	PROPN
bjos-8676163	213	12	,	,	PUNCT
bjos-8676163	213	13	fimland	fimland	ADV
bjos-8676163	213	14	g	g	NOUN
bjos-8676163	213	15	,	,	PUNCT
bjos-8676163	213	16	arntzen	arntzen	ADJ
bjos-8676163	213	17	mø	mø	NOUN
bjos-8676163	213	18	,	,	PUNCT
bjos-8676163	213	19	thiede	thiede	NOUN
bjos-8676163	213	20	b	b	PROPN
bjos-8676163	213	21	,	,	PUNCT
bjos-8676163	213	22	et	et	PROPN
bjos-8676163	213	23	al	al	PROPN
bjos-8676163	213	24	.	.	PROPN
bjos-8676163	213	25	extracellular	extracellular	ADJ
bjos-8676163	213	26	identification	identification	NOUN
bjos-8676163	213	27	of	of	ADP
bjos-8676163	213	28	a	a	DET
bjos-8676163	213	29	processed	process	VERB
bjos-8676163	213	30	type	type	NOUN
bjos-8676163	213	31	ii	ii	NOUN
bjos-8676163	213	32	comr	comr	NOUN
bjos-8676163	213	33	/	/	SYM
bjos-8676163	213	34	coms	com	NOUN
bjos-8676163	213	35	pheromone	pheromone	NOUN
bjos-8676163	213	36	of	of	ADP
bjos-8676163	213	37	streptococcus	streptococcus	NOUN
bjos-8676163	213	38	mutans	mutan	NOUN
bjos-8676163	213	39	.	.	PUNCT
bjos-8676163	214	1	j	j	PROPN
bjos-8676163	214	2	bacteriol	bacteriol	NOUN
bjos-8676163	214	3	.	.	PUNCT
bjos-8676163	215	1	2012	2012	NUM
bjos-8676163	215	2	aug;194(15):3781	aug;194(15):3781	PROPN
bjos-8676163	215	3	-	-	SYM
bjos-8676163	215	4	8	8	NUM
bjos-8676163	215	5	.	.	PUNCT
bjos-8676163	216	1	doi	doi	NOUN
bjos-8676163	216	2	:	:	PUNCT
bjos-8676163	216	3	10.1128	10.1128	NUM
bjos-8676163	216	4	/	/	SYM
bjos-8676163	216	5	jb.00624	jb.00624	PROPN
bjos-8676163	216	6	-	-	NUM
bjos-8676163	216	7	12	12	NUM
bjos-8676163	216	8	.	.	PUNCT
bjos-8676163	217	1	16	16	NUM
bjos-8676163	217	2	.	.	PUNCT
bjos-8676163	218	1	rikvold	rikvold	PROPN
bjos-8676163	218	2	pd	pd	PROPN
bjos-8676163	218	3	,	,	PUNCT
bjos-8676163	218	4	hansen	hansen	PROPN
bjos-8676163	218	5	skov	skov	PROPN
bjos-8676163	218	6	lb	lb	PROPN
bjos-8676163	218	7	,	,	PUNCT
bjos-8676163	218	8	louise	louise	PROPN
bjos-8676163	218	9	meyer	meyer	PROPN
bjos-8676163	218	10	r	r	PROPN
bjos-8676163	218	11	,	,	PUNCT
bjos-8676163	218	12	rose	rise	VERB
bjos-8676163	218	13	jorgensen	jorgensen	PROPN
bjos-8676163	218	14	m	m	PROPN
bjos-8676163	218	15	,	,	PUNCT
bjos-8676163	218	16	tiwari	tiwari	PROPN
bjos-8676163	218	17	mk	mk	X
bjos-8676163	218	18	,	,	PUNCT
bjos-8676163	218	19	schlafer	schlafer	VERB
bjos-8676163	218	20	s.	s.	PROPN
bjos-8676163	218	21	the	the	DET
bjos-8676163	218	22	effect	effect	NOUN
bjos-8676163	218	23	of	of	ADP
bjos-8676163	218	24	enzymatic	enzymatic	ADJ
bjos-8676163	218	25	treatment	treatment	NOUN
bjos-8676163	218	26	with	with	ADP
bjos-8676163	218	27	mutanase	mutanase	NOUN
bjos-8676163	218	28	,	,	PUNCT
bjos-8676163	218	29	beta	beta	NOUN
bjos-8676163	218	30	-	-	PUNCT
bjos-8676163	218	31	glucanase	glucanase	NOUN
bjos-8676163	218	32	and	and	CCONJ
bjos-8676163	218	33	dnase	dnase	NOUN
bjos-8676163	218	34	on	on	ADP
bjos-8676163	218	35	a	a	DET
bjos-8676163	218	36	saliva	saliva	NOUN
bjos-8676163	218	37	-	-	PUNCT
bjos-8676163	218	38	derived	derive	VERB
bjos-8676163	218	39	biofilm	biofilm	NOUN
bjos-8676163	218	40	model	model	NOUN
bjos-8676163	218	41	.	.	PUNCT
bjos-8676163	219	1	caries	carie	NOUN
bjos-8676163	219	2	res	re	NOUN
bjos-8676163	219	3	.	.	PUNCT
bjos-8676163	220	1	2024;58(2):68	2024;58(2):68	NUM
bjos-8676163	220	2	-	-	SYM
bjos-8676163	220	3	76	76	NUM
bjos-8676163	220	4	.	.	PUNCT
bjos-8676163	221	1	doi	doi	NOUN
bjos-8676163	221	2	:	:	PUNCT
bjos-8676163	221	3	10.1159/000535980	10.1159/000535980	NUM
bjos-8676163	221	4	.	.	X
bjos-8676163	221	5	epub	epub	PROPN
bjos-8676163	221	6	2023	2023	NUM
bjos-8676163	221	7	dec	dec	PROPN
bjos-8676163	221	8	28	28	NUM
bjos-8676163	221	9	.	.	PUNCT
bjos-8676163	222	1	17	17	NUM
bjos-8676163	222	2	.	.	PUNCT
bjos-8676163	223	1	davies	davy	NOUN
bjos-8676163	223	2	d.	d.	PROPN
bjos-8676163	223	3	understanding	understand	VERB
bjos-8676163	223	4	biofilm	biofilm	NOUN
bjos-8676163	223	5	resistance	resistance	NOUN
bjos-8676163	223	6	to	to	ADP
bjos-8676163	223	7	antibacterial	antibacterial	ADJ
bjos-8676163	223	8	agents	agent	NOUN
bjos-8676163	223	9	.	.	PUNCT
bjos-8676163	224	1	nat	nat	PROPN
bjos-8676163	224	2	rev	rev	VERB
bjos-8676163	224	3	drug	drug	NOUN
bjos-8676163	224	4	discov	discov	NOUN
bjos-8676163	224	5	.	.	PUNCT
bjos-8676163	225	1	2003	2003	NUM
bjos-8676163	225	2	feb;2(2):114	feb;2(2):114	NOUN
bjos-8676163	225	3	-	-	PUNCT
bjos-8676163	225	4	22	22	NUM
bjos-8676163	225	5	.	.	PUNCT
bjos-8676163	226	1	doi	doi	NOUN
bjos-8676163	226	2	:	:	PUNCT
bjos-8676163	226	3	10.1038	10.1038	NUM
bjos-8676163	226	4	/	/	SYM
bjos-8676163	226	5	nrd1008	nrd1008	NOUN
bjos-8676163	226	6	.	.	PUNCT
bjos-8676163	227	1	18	18	NUM
bjos-8676163	227	2	.	.	PUNCT
bjos-8676163	227	3	penesyan	penesyan	PROPN
bjos-8676163	227	4	a	a	PRON
bjos-8676163	227	5	,	,	PUNCT
bjos-8676163	227	6	nagy	nagy	PROPN
bjos-8676163	227	7	ss	ss	PROPN
bjos-8676163	227	8	,	,	PUNCT
bjos-8676163	227	9	kjelleberg	kjelleberg	PROPN
bjos-8676163	227	10	s	s	PROPN
bjos-8676163	227	11	,	,	PUNCT
bjos-8676163	227	12	gillings	gilling	NOUN
bjos-8676163	227	13	mr	mr	PROPN
bjos-8676163	227	14	,	,	PUNCT
bjos-8676163	227	15	paulsen	paulsen	PROPN
bjos-8676163	227	16	it	it	PRON
bjos-8676163	227	17	.	.	PUNCT
bjos-8676163	228	1	rapid	rapid	ADJ
bjos-8676163	228	2	microevolution	microevolution	NOUN
bjos-8676163	228	3	of	of	ADP
bjos-8676163	228	4	biofilm	biofilm	NOUN
bjos-8676163	228	5	cells	cell	NOUN
bjos-8676163	228	6	in	in	ADP
bjos-8676163	228	7	response	response	NOUN
bjos-8676163	228	8	to	to	ADP
bjos-8676163	228	9	antibiotics	antibiotic	NOUN
bjos-8676163	228	10	.	.	PUNCT
bjos-8676163	229	1	npj	npj	PROPN
bjos-8676163	229	2	biofilms	biofilms	PROPN
bjos-8676163	229	3	microbiomes	microbiomes	PROPN
bjos-8676163	229	4	.	.	PROPN
bjos-8676163	229	5	2019	2019	NUM
bjos-8676163	229	6	nov;5(1):34	nov;5(1):34	NOUN
bjos-8676163	229	7	.	.	PUNCT
bjos-8676163	230	1	doi	doi	PROPN
bjos-8676163	230	2	:	:	PUNCT
bjos-8676163	230	3	10.1038	10.1038	NUM
bjos-8676163	230	4	/	/	SYM
bjos-8676163	230	5	s41522	s41522	NOUN
bjos-8676163	230	6	-	-	PUNCT
bjos-8676163	230	7	019	019	NUM
bjos-8676163	230	8	-	-	PUNCT
bjos-8676163	230	9	0108	0108	NUM
bjos-8676163	230	10	-	-	PUNCT
bjos-8676163	230	11	3	3	NUM
bjos-8676163	230	12	.	.	NOUN
bjos-8676163	230	13	19	19	NUM
bjos-8676163	230	14	.	.	PUNCT
bjos-8676163	231	1	lowry	lowry	PROPN
bjos-8676163	231	2	oh	oh	INTJ
bjos-8676163	231	3	,	,	PUNCT
bjos-8676163	231	4	rosebrough	rosebrough	PROPN
bjos-8676163	231	5	nj	nj	PROPN
bjos-8676163	231	6	,	,	PUNCT
bjos-8676163	231	7	farr	farr	PROPN
bjos-8676163	231	8	al	al	PROPN
bjos-8676163	231	9	,	,	PUNCT
bjos-8676163	231	10	randall	randall	PROPN
bjos-8676163	231	11	rj	rj	PROPN
bjos-8676163	231	12	.	.	PUNCT
bjos-8676163	232	1	protein	protein	NOUN
bjos-8676163	232	2	measurement	measurement	NOUN
bjos-8676163	232	3	with	with	ADP
bjos-8676163	232	4	the	the	DET
bjos-8676163	232	5	folin	folin	PROPN
bjos-8676163	232	6	phenol	phenol	NOUN
bjos-8676163	232	7	reagent	reagent	NOUN
bjos-8676163	232	8	.	.	PUNCT
bjos-8676163	233	1	j	j	PROPN
bjos-8676163	233	2	biol	biol	PROPN
bjos-8676163	233	3	chem	chem	NOUN
bjos-8676163	233	4	.	.	PUNCT
bjos-8676163	234	1	1951	1951	NUM
bjos-8676163	234	2	nov;193(1):265	nov;193(1):265	NOUN
bjos-8676163	234	3	-	-	PUNCT
bjos-8676163	234	4	75	75	NUM
bjos-8676163	234	5	.	.	PUNCT
bjos-8676163	235	1	20	20	NUM
bjos-8676163	235	2	.	.	PUNCT
bjos-8676163	236	1	marsh	marsh	PROPN
bjos-8676163	236	2	pd	pd	PROPN
bjos-8676163	236	3	,	,	PUNCT
bjos-8676163	236	4	moter	moter	NOUN
bjos-8676163	236	5	a	a	PRON
bjos-8676163	236	6	,	,	PUNCT
bjos-8676163	236	7	devine	devine	PROPN
bjos-8676163	236	8	da	da	PROPN
bjos-8676163	236	9	.	.	PUNCT
bjos-8676163	236	10	dental	dental	ADJ
bjos-8676163	236	11	plaque	plaque	NOUN
bjos-8676163	236	12	biofilms	biofilm	NOUN
bjos-8676163	236	13	:	:	PUNCT
bjos-8676163	236	14	communities	community	NOUN
bjos-8676163	236	15	,	,	PUNCT
bjos-8676163	236	16	conflict	conflict	NOUN
bjos-8676163	236	17	and	and	CCONJ
bjos-8676163	236	18	control	control	NOUN
bjos-8676163	236	19	.	.	PUNCT
bjos-8676163	237	1	periodontol	periodontol	NOUN
bjos-8676163	237	2	2000	2000	NUM
bjos-8676163	237	3	.	.	PUNCT
bjos-8676163	238	1	2011	2011	NUM
bjos-8676163	238	2	feb;55(1):16	feb;55(1):16	NOUN
bjos-8676163	238	3	-	-	PUNCT
bjos-8676163	238	4	35	35	NUM
bjos-8676163	238	5	.	.	PUNCT
bjos-8676163	239	1	doi	doi	NOUN
bjos-8676163	239	2	:	:	PUNCT
bjos-8676163	239	3	10.1111	10.1111	NUM
bjos-8676163	239	4	/	/	SYM
bjos-8676163	239	5	j.1600	j.1600	PROPN
bjos-8676163	239	6	-	-	PUNCT
bjos-8676163	239	7	0757.2009.00339.x	0757.2009.00339.x	NOUN
bjos-8676163	239	8	.	.	PUNCT
bjos-8676163	240	1	21	21	NUM
bjos-8676163	240	2	.	.	PUNCT
bjos-8676163	241	1	mattos	mattos	NOUN
bjos-8676163	241	2	-	-	PUNCT
bjos-8676163	241	3	graner	graner	NOUN
bjos-8676163	241	4	ro	ro	NOUN
bjos-8676163	241	5	,	,	PUNCT
bjos-8676163	241	6	smith	smith	PROPN
bjos-8676163	241	7	dj	dj	PROPN
bjos-8676163	241	8	,	,	PUNCT
bjos-8676163	241	9	king	king	PROPN
bjos-8676163	241	10	wf	wf	PROPN
bjos-8676163	241	11	,	,	PUNCT
bjos-8676163	241	12	mayer	mayer	PROPN
bjos-8676163	241	13	mp	mp	PROPN
bjos-8676163	241	14	.	.	PROPN
bjos-8676163	241	15	water	water	NOUN
bjos-8676163	241	16	-	-	PUNCT
bjos-8676163	241	17	insoluble	insoluble	ADJ
bjos-8676163	241	18	glucan	glucan	NOUN
bjos-8676163	241	19	synthesis	synthesis	NOUN
bjos-8676163	241	20	by	by	ADP
bjos-8676163	241	21	mutans	mutan	NOUN
bjos-8676163	241	22	streptococcal	streptococcal	ADJ
bjos-8676163	241	23	strains	strain	NOUN
bjos-8676163	241	24	correlates	correlate	VERB
bjos-8676163	241	25	with	with	ADP
bjos-8676163	241	26	caries	carie	NOUN
bjos-8676163	241	27	incidence	incidence	NOUN
bjos-8676163	241	28	in	in	ADP
bjos-8676163	241	29	12to	12to	ADJ
bjos-8676163	241	30	30	30	NUM
bjos-8676163	241	31	-	-	PUNCT
bjos-8676163	241	32	month	month	NOUN
bjos-8676163	241	33	-	-	PUNCT
bjos-8676163	241	34	old	old	ADJ
bjos-8676163	241	35	children	child	NOUN
bjos-8676163	241	36	.	.	PUNCT
bjos-8676163	242	1	j	j	PROPN
bjos-8676163	242	2	dent	dent	NOUN
bjos-8676163	242	3	res	re	NOUN
bjos-8676163	242	4	.	.	PUNCT
bjos-8676163	242	5	2000	2000	NUM
bjos-8676163	243	1	jun;79(6):1371	jun;79(6):1371	NOUN
bjos-8676163	243	2	-	-	PUNCT
bjos-8676163	243	3	7	7	NUM
bjos-8676163	243	4	.	.	PUNCT
bjos-8676163	243	5	doi	doi	NOUN
bjos-8676163	243	6	:	:	PUNCT
bjos-8676163	243	7	10.1177/00220345000790060401	10.1177/00220345000790060401	NUM
bjos-8676163	243	8	.	.	PUNCT
bjos-8676163	243	9	22	22	NUM
bjos-8676163	243	10	.	.	PUNCT
bjos-8676163	244	1	mattos	mattos	NOUN
bjos-8676163	244	2	-	-	PUNCT
bjos-8676163	244	3	graner	graner	NOUN
bjos-8676163	244	4	ro	ro	NOUN
bjos-8676163	244	5	,	,	PUNCT
bjos-8676163	244	6	zelante	zelante	PROPN
bjos-8676163	244	7	f	f	PROPN
bjos-8676163	244	8	,	,	PUNCT
bjos-8676163	244	9	line	line	PROPN
bjos-8676163	244	10	rc	rc	PROPN
bjos-8676163	244	11	,	,	PUNCT
bjos-8676163	244	12	mayer	mayer	PROPN
bjos-8676163	244	13	mp	mp	PROPN
bjos-8676163	244	14	.	.	PROPN
bjos-8676163	244	15	association	association	PROPN
bjos-8676163	244	16	between	between	ADP
bjos-8676163	244	17	caries	carie	NOUN
bjos-8676163	244	18	prevalence	prevalence	NOUN
bjos-8676163	244	19	and	and	CCONJ
bjos-8676163	244	20	clinical	clinical	ADJ
bjos-8676163	244	21	,	,	PUNCT
bjos-8676163	244	22	microbiological	microbiological	ADJ
bjos-8676163	244	23	and	and	CCONJ
bjos-8676163	244	24	dietary	dietary	ADJ
bjos-8676163	244	25	variables	variable	NOUN
bjos-8676163	244	26	in	in	ADP
bjos-8676163	244	27	1.0	1.0	NUM
bjos-8676163	244	28	to	to	PART
bjos-8676163	244	29	2.5	2.5	NUM
bjos-8676163	244	30	-	-	PUNCT
bjos-8676163	244	31	year	year	NOUN
bjos-8676163	244	32	-	-	PUNCT
bjos-8676163	244	33	old	old	ADJ
bjos-8676163	244	34	brazilian	brazilian	ADJ
bjos-8676163	244	35	children	child	NOUN
bjos-8676163	244	36	.	.	PUNCT
bjos-8676163	245	1	caries	carie	NOUN
bjos-8676163	245	2	res	re	NOUN
bjos-8676163	245	3	.	.	PUNCT
bjos-8676163	246	1	1998;32(5):319	1998;32(5):319	NUM
bjos-8676163	246	2	-	-	PUNCT
bjos-8676163	246	3	23	23	NUM
bjos-8676163	246	4	.	.	PUNCT
bjos-8676163	247	1	doi	doi	NOUN
bjos-8676163	247	2	:	:	PUNCT
bjos-8676163	247	3	10.1159/000016466	10.1159/000016466	NUM
bjos-8676163	247	4	.	.	NOUN
bjos-8676163	247	5	23	23	NUM
bjos-8676163	247	6	.	.	PUNCT
bjos-8676163	248	1	nobre	nobre	PROPN
bjos-8676163	248	2	dos	dos	PROPN
bjos-8676163	248	3	santos	santos	PROPN
bjos-8676163	248	4	m	m	PROPN
bjos-8676163	248	5	,	,	PUNCT
bjos-8676163	248	6	melo	melo	PROPN
bjos-8676163	248	7	dos	do	VERB
bjos-8676163	248	8	santos	santos	PROPN
bjos-8676163	248	9	l	l	PROPN
bjos-8676163	248	10	,	,	PUNCT
bjos-8676163	248	11	francisco	francisco	PROPN
bjos-8676163	248	12	sb	sb	PROPN
bjos-8676163	248	13	,	,	PUNCT
bjos-8676163	248	14	cury	cury	PROPN
bjos-8676163	248	15	ja	ja	PROPN
bjos-8676163	248	16	.	.	PROPN
bjos-8676163	248	17	relationship	relationship	NOUN
bjos-8676163	248	18	among	among	ADP
bjos-8676163	248	19	dental	dental	ADJ
bjos-8676163	248	20	plaque	plaque	NOUN
bjos-8676163	248	21	composition	composition	NOUN
bjos-8676163	248	22	,	,	PUNCT
bjos-8676163	248	23	daily	daily	ADJ
bjos-8676163	248	24	sugar	sugar	NOUN
bjos-8676163	248	25	exposure	exposure	NOUN
bjos-8676163	248	26	and	and	CCONJ
bjos-8676163	248	27	caries	carie	NOUN
bjos-8676163	248	28	in	in	ADP
bjos-8676163	248	29	the	the	DET
bjos-8676163	248	30	primary	primary	ADJ
bjos-8676163	248	31	dentition	dentition	NOUN
bjos-8676163	248	32	.	.	PUNCT
bjos-8676163	249	1	caries	carie	NOUN
bjos-8676163	249	2	res	re	NOUN
bjos-8676163	249	3	.	.	PUNCT
bjos-8676163	249	4	2002	2002	NUM
bjos-8676163	249	5	sepoct;36(5):347	sepoct;36(5):347	PROPN
bjos-8676163	249	6	-	-	SYM
bjos-8676163	249	7	52	52	NUM
bjos-8676163	249	8	.	.	PUNCT
bjos-8676163	250	1	doi	doi	NOUN
bjos-8676163	250	2	:	:	PUNCT
bjos-8676163	250	3	10.1159/000065959	10.1159/000065959	NUM
bjos-8676163	250	4	.	.	PUNCT