id	sid	tid	token	lemma	pos
can-1681	1	1	characterization	characterization	NOUN
can-1681	1	2	and	and	CCONJ
can-1681	1	3	application	application	NOUN
can-1681	1	4	of	of	ADP
can-1681	1	5	nanomaterials	nanomaterial	NOUN
can-1681	1	6	(	(	PUNCT
can-1681	1	7	2022	2022	NUM
can-1681	1	8	)	)	PUNCT
can-1681	1	9	volume	volume	NOUN
can-1681	1	10	5	5	NUM
can-1681	1	11	issue	issue	NOUN
can-1681	1	12	1	1	NUM
can-1681	1	13	doi:10.24294	doi:10.24294	NOUN
can-1681	1	14	/	/	SYM
can-1681	2	1	can.v5i1.1681	can.v5i1.1681	PROPN
can-1681	2	2	66	66	NUM
can-1681	2	3	review	review	NOUN
can-1681	2	4	article	article	NOUN
can-1681	2	5	application	application	NOUN
can-1681	2	6	of	of	ADP
can-1681	2	7	nanotechnology	nanotechnology	NOUN
can-1681	2	8	in	in	ADP
can-1681	2	9	ophthalmology	ophthalmology	NOUN
can-1681	2	10	:	:	PUNCT
can-1681	2	11	where	where	SCONJ
can-1681	2	12	are	be	AUX
can-1681	2	13	we	we	PRON
can-1681	2	14	?	?	PUNCT
can-1681	3	1	marcela	marcela	PROPN
can-1681	3	2	gómez	gómez	NOUN
can-1681	3	3	-	-	PUNCT
can-1681	3	4	garzón1	garzón1	NOUN
can-1681	3	5	,	,	PUNCT
can-1681	3	6	m.	m.	NOUN
can-1681	3	7	alejandra	alejandra	PROPN
can-1681	3	8	martínez	martínez	PROPN
can-1681	3	9	-	-	PUNCT
can-1681	3	10	ceballos1	ceballos1	PROPN
can-1681	3	11	*	*	NOUN
can-1681	3	12	,	,	PUNCT
can-1681	3	13	arley	arley	PROPN
can-1681	3	14	gómez	gómez	PROPN
can-1681	3	15	-	-	PUNCT
can-1681	3	16	lópez1,2	lópez1,2	PROPN
can-1681	3	17	,	,	PUNCT
can-1681	3	18	adriana	adriana	PROPN
can-1681	3	19	rojas	rojas	PROPN
can-1681	3	20	-	-	PUNCT
can-1681	3	21	villarraga1,2	villarraga1,2	PROPN
can-1681	3	22	1	1	NUM
can-1681	3	23	división	división	X
can-1681	3	24	de	de	X
can-1681	3	25	investigaciones	investigaciones	PROPN
can-1681	3	26	,	,	PUNCT
can-1681	3	27	fucs	fucs	NOUN
can-1681	3	28	,	,	PUNCT
can-1681	3	29	cl	cl	NOUN
can-1681	3	30	.	.	PUNCT
can-1681	4	1	10#18	10#18	NUM
can-1681	4	2	-	-	SYM
can-1681	4	3	75	75	NUM
can-1681	4	4	,	,	PUNCT
can-1681	4	5	bogotá	bogotá	NOUN
can-1681	4	6	,	,	PUNCT
can-1681	4	7	colombia	colombia	PROPN
can-1681	4	8	.	.	PUNCT
can-1681	5	1	e	e	X
can-1681	5	2	-	-	NOUN
can-1681	5	3	mail	mail	NOUN
can-1681	5	4	:	:	PUNCT
can-1681	5	5	mariamace9@gmail.com	mariamace9@gmail.com	PROPN
can-1681	5	6	2	2	NUM
can-1681	5	7	instituto	instituto	PROPN
can-1681	5	8	de	de	PROPN
can-1681	5	9	investigaciones	investigaciones	PROPN
can-1681	5	10	.	.	PUNCT
can-1681	6	1	fundación	fundación	PROPN
can-1681	6	2	universitaria	universitaria	PROPN
can-1681	6	3	de	de	PROPN
can-1681	6	4	ciencias	ciencias	PROPN
can-1681	6	5	de	de	PROPN
can-1681	6	6	la	la	PROPN
can-1681	6	7	salud	salud	PROPN
can-1681	6	8	(	(	PUNCT
can-1681	6	9	fucs	fucs	NOUN
can-1681	6	10	)	)	PUNCT
can-1681	6	11	,	,	PUNCT
can-1681	6	12	bogotá	bogotá	NOUN
can-1681	6	13	,	,	PUNCT
can-1681	6	14	colombia	colombia	PROPN
can-1681	6	15	abstract	abstract	ADJ
can-1681	6	16	nanotechnology	nanotechnology	PROPN
can-1681	6	17	is	be	AUX
can-1681	6	18	a	a	DET
can-1681	6	19	subject	subject	NOUN
can-1681	6	20	that	that	SCONJ
can-1681	6	21	studies	study	NOUN
can-1681	6	22	,	,	PUNCT
can-1681	6	23	processes	process	NOUN
can-1681	6	24	,	,	PUNCT
can-1681	6	25	and	and	CCONJ
can-1681	6	26	applies	apply	VERB
can-1681	6	27	various	various	ADJ
can-1681	6	28	functional	functional	ADJ
can-1681	6	29	materials	material	NOUN
can-1681	6	30	,	,	PUNCT
can-1681	6	31	equipment	equipment	NOUN
can-1681	6	32	,	,	PUNCT
can-1681	6	33	and	and	CCONJ
can-1681	6	34	systems	system	NOUN
can-1681	6	35	,	,	PUNCT
can-1681	6	36	and	and	CCONJ
can-1681	6	37	controls	control	VERB
can-1681	6	38	substances	substance	NOUN
can-1681	6	39	on	on	ADP
can-1681	6	40	a	a	DET
can-1681	6	41	nanoscale	nanoscale	NOUN
can-1681	6	42	.	.	PUNCT
can-1681	7	1	nanomedicine	nanomedicine	PROPN
can-1681	7	2	refers	refer	VERB
can-1681	7	3	to	to	ADP
can-1681	7	4	its	its	PRON
can-1681	7	5	application	application	NOUN
can-1681	7	6	in	in	ADP
can-1681	7	7	diagnosing	diagnosing	NOUN
can-1681	7	8	,	,	PUNCT
can-1681	7	9	treating	treat	VERB
can-1681	7	10	,	,	PUNCT
can-1681	7	11	preventing	prevent	VERB
can-1681	7	12	,	,	PUNCT
can-1681	7	13	and	and	CCONJ
can-1681	7	14	monitoring	monitor	VERB
can-1681	7	15	various	various	ADJ
can-1681	7	16	diseases	disease	NOUN
can-1681	7	17	.	.	PUNCT
can-1681	8	1	drugs	drug	NOUN
can-1681	8	2	administered	administer	VERB
can-1681	8	3	through	through	ADP
can-1681	8	4	eye	eye	NOUN
can-1681	8	5	drops	drop	NOUN
can-1681	8	6	must	must	AUX
can-1681	8	7	travel	travel	VERB
can-1681	8	8	a	a	DET
can-1681	8	9	long	long	ADJ
can-1681	8	10	distance	distance	NOUN
can-1681	8	11	to	to	PART
can-1681	8	12	avoid	avoid	VERB
can-1681	8	13	various	various	ADJ
can-1681	8	14	eye	eye	NOUN
can-1681	8	15	barriers	barrier	NOUN
can-1681	8	16	reaching	reach	VERB
can-1681	8	17	the	the	DET
can-1681	8	18	posterior	posterior	ADJ
can-1681	8	19	segment	segment	NOUN
can-1681	8	20	of	of	ADP
can-1681	8	21	the	the	DET
can-1681	8	22	eye	eye	NOUN
can-1681	8	23	,	,	PUNCT
can-1681	8	24	to	to	PART
can-1681	8	25	achieve	achieve	VERB
can-1681	8	26	the	the	DET
can-1681	8	27	lowest	low	ADJ
can-1681	8	28	drug	drug	NOUN
can-1681	8	29	level	level	NOUN
can-1681	8	30	.	.	PUNCT
can-1681	9	1	this	this	DET
can-1681	9	2	review	review	NOUN
can-1681	9	3	focuses	focus	VERB
can-1681	9	4	on	on	ADP
can-1681	9	5	nanotechnology	nanotechnology	NOUN
can-1681	9	6	-	-	PUNCT
can-1681	9	7	based	base	VERB
can-1681	9	8	eye	eye	NOUN
can-1681	9	9	disease	disease	NOUN
can-1681	9	10	treatment	treatment	NOUN
can-1681	9	11	systems	system	NOUN
can-1681	9	12	and	and	CCONJ
can-1681	9	13	highlights	highlight	NOUN
can-1681	9	14	the	the	DET
can-1681	9	15	obstacles	obstacle	NOUN
can-1681	9	16	affecting	affect	VERB
can-1681	9	17	the	the	DET
can-1681	9	18	drug	drug	NOUN
can-1681	9	19	management	management	NOUN
can-1681	9	20	of	of	ADP
can-1681	9	21	eyes	eye	NOUN
can-1681	9	22	and	and	CCONJ
can-1681	9	23	nano	nano	NOUN
can-1681	9	24	-	-	PUNCT
can-1681	9	25	systems	system	NOUN
can-1681	9	26	for	for	ADP
can-1681	9	27	the	the	DET
can-1681	9	28	treatment	treatment	NOUN
can-1681	9	29	of	of	ADP
can-1681	9	30	eye	eye	NOUN
can-1681	9	31	diseases	disease	NOUN
can-1681	9	32	.	.	PUNCT
can-1681	10	1	this	this	DET
can-1681	10	2	paper	paper	NOUN
can-1681	10	3	summarizes	summarize	VERB
can-1681	10	4	the	the	DET
can-1681	10	5	development	development	NOUN
can-1681	10	6	prospect	prospect	NOUN
can-1681	10	7	of	of	ADP
can-1681	10	8	nanotechnology	nanotechnology	NOUN
can-1681	10	9	and	and	CCONJ
can-1681	10	10	the	the	DET
can-1681	10	11	challenges	challenge	NOUN
can-1681	10	12	it	it	PRON
can-1681	10	13	faces	face	VERB
can-1681	10	14	in	in	ADP
can-1681	10	15	the	the	DET
can-1681	10	16	treatment	treatment	NOUN
can-1681	10	17	and	and	CCONJ
can-1681	10	18	diagnosis	diagnosis	NOUN
can-1681	10	19	of	of	ADP
can-1681	10	20	ophthalmic	ophthalmic	ADJ
can-1681	10	21	diseases	disease	NOUN
can-1681	10	22	,	,	PUNCT
can-1681	10	23	to	to	PART
can-1681	10	24	provide	provide	VERB
can-1681	10	25	information	information	NOUN
can-1681	10	26	and	and	CCONJ
can-1681	10	27	new	new	ADJ
can-1681	10	28	ideas	idea	NOUN
can-1681	10	29	for	for	ADP
can-1681	10	30	the	the	DET
can-1681	10	31	implementation	implementation	NOUN
can-1681	10	32	of	of	ADP
can-1681	10	33	treatment	treatment	NOUN
can-1681	10	34	and	and	CCONJ
can-1681	10	35	the	the	DET
can-1681	10	36	development	development	NOUN
can-1681	10	37	of	of	ADP
can-1681	10	38	a	a	DET
can-1681	10	39	refractory	refractory	NOUN
can-1681	10	40	eye	eye	NOUN
can-1681	10	41	disease	disease	NOUN
can-1681	10	42	management	management	NOUN
can-1681	10	43	system	system	NOUN
can-1681	10	44	.	.	PUNCT
can-1681	11	1	keywords	keyword	NOUN
can-1681	11	2	:	:	PUNCT
can-1681	11	3	ophthalmology	ophthalmology	NOUN
can-1681	11	4	nanotechnology	nanotechnology	NOUN
can-1681	11	5	;	;	PUNCT
can-1681	11	6	nanomedicine	nanomedicine	NOUN
can-1681	11	7	;	;	PUNCT
can-1681	11	8	nanoparticles	nanoparticle	NOUN
can-1681	11	9	article	article	NOUN
can-1681	11	10	info	info	NOUN
can-1681	11	11	received	receive	VERB
can-1681	11	12	:	:	PUNCT
can-1681	11	13	18	18	NUM
can-1681	11	14	january	january	PROPN
can-1681	11	15	2022	2022	NUM
can-1681	11	16	accepted	accept	VERB
can-1681	11	17	:	:	PUNCT
can-1681	11	18	20	20	NUM
can-1681	11	19	march	march	NOUN
can-1681	11	20	2022	2022	NUM
can-1681	11	21	available	available	ADJ
can-1681	11	22	online	online	ADV
can-1681	11	23	:	:	PUNCT
can-1681	11	24	31	31	NUM
can-1681	11	25	march	march	NOUN
can-1681	11	26	2022	2022	NUM
can-1681	11	27	copyright	copyright	NOUN
can-1681	11	28	copyright	copyright	NOUN
can-1681	11	29	©	©	PROPN
can-1681	11	30	2022	2022	NUM
can-1681	11	31	marcela	marcela	PROPN
can-1681	11	32	gómez	gómez	NOUN
can-1681	11	33	-	-	PUNCT
can-1681	11	34	garzón	garzón	PROPN
can-1681	11	35	,	,	PUNCT
can-1681	11	36	et	et	PROPN
can-1681	11	37	al	al	PROPN
can-1681	11	38	.	.	PROPN
can-1681	11	39	enpress	enpress	PROPN
can-1681	11	40	publisher	publisher	PROPN
can-1681	11	41	llc	llc	PROPN
can-1681	11	42	.	.	PUNCT
can-1681	12	1	this	this	DET
can-1681	12	2	work	work	NOUN
can-1681	12	3	is	be	AUX
can-1681	12	4	licensed	license	VERB
can-1681	12	5	under	under	ADP
can-1681	12	6	the	the	DET
can-1681	12	7	creative	creative	ADJ
can-1681	12	8	commons	common	NOUN
can-1681	12	9	attribution	attribution	NOUN
can-1681	12	10	-	-	PUNCT
can-1681	12	11	noncommercial	noncommercial	ADJ
can-1681	12	12	4.0	4.0	NUM
can-1681	12	13	international	international	ADJ
can-1681	12	14	license	license	NOUN
can-1681	12	15	(	(	PUNCT
can-1681	12	16	cc	cc	NOUN
can-1681	12	17	by	by	ADP
can-1681	12	18	-	-	PUNCT
can-1681	12	19	nc	nc	PROPN
can-1681	12	20	4.0	4.0	NUM
can-1681	12	21	)	)	PUNCT
can-1681	12	22	.	.	PUNCT
can-1681	13	1	https://creativecommons.org/licenses/by-nc/	https://creativecommons.org/licenses/by-nc/	PROPN
can-1681	13	2	4.0/	4.0/	NUM
can-1681	13	3	1	1	NUM
can-1681	13	4	.	.	PUNCT
can-1681	14	1	introduction	introduction	NOUN
can-1681	14	2	the	the	DET
can-1681	14	3	world	world	PROPN
can-1681	14	4	health	health	NOUN
can-1681	14	5	organization	organization	NOUN
can-1681	14	6	estimates	estimate	VERB
can-1681	14	7	that	that	SCONJ
can-1681	14	8	in	in	ADP
can-1681	14	9	2018	2018	NUM
can-1681	14	10	,	,	PUNCT
can-1681	14	11	about	about	ADV
can-1681	14	12	1.3	1.3	NUM
can-1681	14	13	billion	billion	NUM
can-1681	14	14	people	people	NOUN
can-1681	14	15	suffered	suffer	VERB
can-1681	14	16	from	from	ADP
can-1681	14	17	some	some	DET
can-1681	14	18	form	form	NOUN
can-1681	14	19	of	of	ADP
can-1681	14	20	visual	visual	ADJ
can-1681	14	21	impairment	impairment	NOUN
can-1681	14	22	,	,	PUNCT
can-1681	14	23	mainly	mainly	ADV
can-1681	14	24	due	due	ADP
can-1681	14	25	to	to	ADP
can-1681	14	26	uncorrected	uncorrected	ADJ
can-1681	14	27	ametropia	ametropia	NOUN
can-1681	14	28	and	and	CCONJ
can-1681	14	29	cataracts	cataract	NOUN
can-1681	14	30	.	.	PUNCT
can-1681	15	1	about	about	ADV
can-1681	15	2	36	36	NUM
can-1681	15	3	million	million	NUM
can-1681	15	4	blind	blind	ADJ
can-1681	15	5	people	people	NOUN
can-1681	15	6	are	be	AUX
can-1681	15	7	blind	blind	ADJ
can-1681	15	8	due	due	ADP
can-1681	15	9	to	to	ADP
can-1681	15	10	cataracts	cataract	NOUN
can-1681	15	11	,	,	PUNCT
can-1681	15	12	trachoma	trachoma	NOUN
can-1681	15	13	,	,	PUNCT
can-1681	15	14	corneal	corneal	ADJ
can-1681	15	15	scar	scar	NOUN
can-1681	15	16	,	,	PUNCT
can-1681	15	17	glaucoma	glaucoma	NOUN
can-1681	15	18	,	,	PUNCT
can-1681	15	19	diabetic	diabetic	ADJ
can-1681	15	20	retinopathy	retinopathy	NOUN
can-1681	15	21	,	,	PUNCT
can-1681	15	22	age	age	NOUN
can-1681	15	23	-	-	PUNCT
can-1681	15	24	related	relate	VERB
can-1681	15	25	macular	macular	ADJ
can-1681	15	26	degeneration	degeneration	NOUN
can-1681	15	27	,	,	PUNCT
can-1681	15	28	and	and	CCONJ
can-1681	15	29	congenital	congenital	ADJ
can-1681	15	30	malformations	malformation	NOUN
can-1681	15	31	.	.	PUNCT
can-1681	16	1	it	it	PRON
can-1681	16	2	is	be	AUX
can-1681	16	3	estimated	estimate	VERB
can-1681	16	4	that	that	SCONJ
can-1681	16	5	80	80	NUM
can-1681	16	6	percent	percent	NOUN
can-1681	16	7	of	of	ADP
can-1681	16	8	these	these	DET
can-1681	16	9	cases	case	NOUN
can-1681	16	10	could	could	AUX
can-1681	16	11	have	have	AUX
can-1681	16	12	been	be	AUX
can-1681	16	13	avoided	avoid	VERB
can-1681	16	14	.	.	PUNCT
can-1681	17	1	the	the	DET
can-1681	17	2	eyes	eye	NOUN
can-1681	17	3	are	be	AUX
can-1681	17	4	divided	divide	VERB
can-1681	17	5	into	into	ADP
can-1681	17	6	anterior	anterior	ADJ
can-1681	17	7	and	and	CCONJ
can-1681	17	8	posterior	posterior	ADJ
can-1681	17	9	segments	segment	NOUN
can-1681	17	10	.	.	PUNCT
can-1681	18	1	the	the	DET
can-1681	18	2	anterior	anterior	ADJ
can-1681	18	3	segment	segment	NOUN
can-1681	18	4	includes	include	VERB
can-1681	18	5	the	the	DET
can-1681	18	6	cornea	cornea	NOUN
can-1681	18	7	,	,	PUNCT
can-1681	18	8	conjunctiva	conjunctiva	NOUN
can-1681	18	9	,	,	PUNCT
can-1681	18	10	anterior	anterior	ADJ
can-1681	18	11	chamber	chamber	PROPN
can-1681	18	12	,	,	PUNCT
can-1681	18	13	iris	iris	NOUN
can-1681	18	14	,	,	PUNCT
can-1681	18	15	ciliary	ciliary	ADJ
can-1681	18	16	body	body	NOUN
can-1681	18	17	,	,	PUNCT
can-1681	18	18	and	and	CCONJ
can-1681	18	19	lens	len	NOUN
can-1681	18	20	.	.	PUNCT
can-1681	19	1	eye	eye	NOUN
can-1681	19	2	drops	drop	NOUN
can-1681	19	3	are	be	AUX
can-1681	19	4	widely	widely	ADV
can-1681	19	5	used	use	VERB
can-1681	19	6	in	in	ADP
can-1681	19	7	the	the	DET
can-1681	19	8	treatment	treatment	NOUN
can-1681	19	9	of	of	ADP
can-1681	19	10	anterior	anterior	ADJ
can-1681	19	11	segment	segment	NOUN
can-1681	19	12	diseases	disease	NOUN
can-1681	19	13	because	because	SCONJ
can-1681	19	14	of	of	ADP
can-1681	19	15	their	their	PRON
can-1681	19	16	accessibility	accessibility	NOUN
can-1681	19	17	.	.	PUNCT
can-1681	20	1	however	however	ADV
can-1681	20	2	,	,	PUNCT
can-1681	20	3	due	due	ADP
can-1681	20	4	to	to	ADP
can-1681	20	5	the	the	DET
can-1681	20	6	corneal	corneal	ADJ
can-1681	20	7	barrier	barrier	NOUN
can-1681	20	8	and	and	CCONJ
can-1681	20	9	the	the	DET
can-1681	20	10	rapid	rapid	ADJ
can-1681	20	11	filtration	filtration	NOUN
can-1681	20	12	of	of	ADP
can-1681	20	13	tears	tear	NOUN
can-1681	20	14	,	,	PUNCT
can-1681	20	15	the	the	DET
can-1681	20	16	bioavailability	bioavailability	NOUN
can-1681	20	17	of	of	ADP
can-1681	20	18	topical	topical	ADJ
can-1681	20	19	eye	eye	NOUN
can-1681	20	20	drops	drop	NOUN
can-1681	20	21	is	be	AUX
can-1681	20	22	poor	poor	ADJ
can-1681	20	23	.	.	PUNCT
can-1681	21	1	the	the	DET
can-1681	21	2	posterior	posterior	ADJ
can-1681	21	3	segment	segment	NOUN
can-1681	21	4	is	be	AUX
can-1681	21	5	composed	compose	VERB
can-1681	21	6	of	of	ADP
can-1681	21	7	the	the	DET
can-1681	21	8	choroid	choroid	NOUN
can-1681	21	9	,	,	PUNCT
can-1681	21	10	vitreous	vitreous	ADJ
can-1681	21	11	,	,	PUNCT
can-1681	21	12	and	and	CCONJ
can-1681	21	13	retina	retina	NOUN
can-1681	21	14	.	.	PUNCT
can-1681	22	1	eye	eye	NOUN
can-1681	22	2	drops	drop	NOUN
can-1681	22	3	must	must	AUX
can-1681	22	4	go	go	VERB
can-1681	22	5	through	through	ADP
can-1681	22	6	a	a	DET
can-1681	22	7	long	long	ADJ
can-1681	22	8	distance	distance	NOUN
can-1681	22	9	and	and	CCONJ
can-1681	22	10	pass	pass	VERB
can-1681	22	11	through	through	ADP
can-1681	22	12	several	several	ADJ
can-1681	22	13	eye	eye	NOUN
can-1681	22	14	barriers	barrier	NOUN
can-1681	22	15	to	to	PART
can-1681	22	16	reach	reach	VERB
can-1681	22	17	the	the	DET
can-1681	22	18	posterior	posterior	ADJ
can-1681	22	19	pole	pole	NOUN
can-1681	22	20	of	of	ADP
can-1681	22	21	the	the	DET
can-1681	22	22	eye	eye	NOUN
can-1681	22	23	,	,	PUNCT
can-1681	22	24	which	which	PRON
can-1681	22	25	leads	lead	VERB
can-1681	22	26	to	to	ADP
can-1681	22	27	low	low	ADJ
can-1681	22	28	bioavailability	bioavailability	NOUN
can-1681	22	29	when	when	SCONJ
can-1681	22	30	the	the	DET
can-1681	22	31	drug	drug	NOUN
can-1681	22	32	reaches	reach	VERB
can-1681	22	33	its	its	PRON
can-1681	22	34	action	action	NOUN
can-1681	22	35	site[2	site[2	NOUN
can-1681	22	36	]	]	PUNCT
can-1681	22	37	.	.	PUNCT
can-1681	23	1	nanotechnology	nanotechnology	PROPN
can-1681	23	2	is	be	AUX
can-1681	23	3	a	a	DET
can-1681	23	4	discipline	discipline	NOUN
can-1681	23	5	that	that	PRON
can-1681	23	6	studies	study	NOUN
can-1681	23	7	,	,	PUNCT
can-1681	23	8	designs	design	NOUN
can-1681	23	9	,	,	PUNCT
can-1681	23	10	synthesizes	synthesize	NOUN
can-1681	23	11	,	,	PUNCT
can-1681	23	12	operates	operate	NOUN
can-1681	23	13	,	,	PUNCT
can-1681	23	14	and	and	CCONJ
can-1681	23	15	applies	apply	VERB
can-1681	23	16	various	various	ADJ
can-1681	23	17	functional	functional	ADJ
can-1681	23	18	materials	material	NOUN
can-1681	23	19	,	,	PUNCT
can-1681	23	20	equipment	equipment	NOUN
can-1681	23	21	,	,	PUNCT
can-1681	23	22	and	and	CCONJ
can-1681	23	23	systems	system	NOUN
can-1681	23	24	,	,	PUNCT
can-1681	23	25	and	and	CCONJ
can-1681	23	26	controls	control	VERB
can-1681	23	27	substances	substance	NOUN
can-1681	23	28	at	at	ADP
can-1681	23	29	the	the	DET
can-1681	23	30	nanoscale	nanoscale	NOUN
can-1681	23	31	(	(	PUNCT
can-1681	23	32	1–100	1–100	NUM
can-1681	23	33	nm	nm	NOUN
can-1681	23	34	)	)	PUNCT
can-1681	23	35	.	.	PUNCT
can-1681	24	1	according	accord	VERB
can-1681	24	2	to	to	ADP
can-1681	24	3	the	the	DET
can-1681	24	4	national	national	ADJ
can-1681	24	5	nanotechnology	nanotechnology	PROPN
can-1681	24	6	initiative	initiative	NOUN
can-1681	24	7	,	,	PUNCT
can-1681	24	8	the	the	DET
can-1681	24	9	essence	essence	NOUN
can-1681	24	10	of	of	ADP
can-1681	24	11	nanotechnology	nanotechnology	NOUN
can-1681	24	12	is	be	AUX
can-1681	24	13	the	the	DET
can-1681	24	14	ability	ability	NOUN
can-1681	24	15	to	to	PART
can-1681	24	16	work	work	VERB
can-1681	24	17	atom	atom	NOUN
can-1681	24	18	by	by	ADP
can-1681	24	19	atom	atom	NOUN
can-1681	24	20	at	at	ADP
can-1681	24	21	the	the	DET
can-1681	24	22	molecular	molecular	ADJ
can-1681	24	23	level	level	NOUN
can-1681	24	24	in	in	ADP
can-1681	24	25	order	order	NOUN
can-1681	24	26	to	to	PART
can-1681	24	27	create	create	VERB
can-1681	24	28	a	a	DET
can-1681	24	29	huge	huge	ADJ
can-1681	24	30	structure	structure	NOUN
can-1681	24	31	and	and	CCONJ
can-1681	24	32	a	a	DET
can-1681	24	33	new	new	ADJ
can-1681	24	34	molecular	molecular	ADJ
can-1681	24	35	organization	organization	NOUN
can-1681	24	36	.	.	PUNCT
can-1681	25	1	the	the	DET
can-1681	25	2	aim	aim	NOUN
can-1681	25	3	is	be	AUX
can-1681	25	4	to	to	PART
can-1681	25	5	develop	develop	VERB
can-1681	25	6	these	these	DET
can-1681	25	7	properties	property	NOUN
can-1681	25	8	by	by	ADP
can-1681	25	9	controlling	control	VERB
can-1681	25	10	structures	structure	NOUN
can-1681	25	11	and	and	CCONJ
can-1681	25	12	devices	device	NOUN
can-1681	25	13	at	at	ADP
can-1681	25	14	the	the	DET
can-1681	25	15	atomic	atomic	ADJ
can-1681	25	16	,	,	PUNCT
can-1681	25	17	molecular	molecular	ADJ
can-1681	25	18	,	,	PUNCT
can-1681	25	19	and	and	CCONJ
can-1681	25	20	supramolecular	supramolecular	ADJ
can-1681	25	21	levels	level	NOUN
can-1681	25	22	,	,	PUNCT
can-1681	25	23	and	and	CCONJ
can-1681	25	24	to	to	PART
can-1681	25	25	learn	learn	VERB
can-1681	25	26	how	how	SCONJ
can-1681	25	27	to	to	PART
can-1681	25	28	67	67	NUM
can-1681	25	29	manufacture	manufacture	NOUN
can-1681	25	30	and	and	CCONJ
can-1681	25	31	use	use	VERB
can-1681	25	32	these	these	DET
can-1681	25	33	devices	device	NOUN
can-1681	25	34	efficiently	efficiently	ADV
can-1681	25	35	.	.	PUNCT
can-1681	26	1	it	it	PRON
can-1681	26	2	can	can	AUX
can-1681	26	3	be	be	AUX
can-1681	26	4	used	use	VERB
can-1681	26	5	to	to	PART
can-1681	26	6	diagnose	diagnose	VERB
can-1681	26	7	,	,	PUNCT
can-1681	26	8	treat	treat	NOUN
can-1681	26	9	,	,	PUNCT
can-1681	26	10	prevent	prevent	VERB
can-1681	26	11	and	and	CCONJ
can-1681	26	12	monitor	monitor	VERB
can-1681	26	13	various	various	ADJ
can-1681	26	14	diseases	disease	NOUN
can-1681	26	15	.	.	PUNCT
can-1681	27	1	nanotechnology	nanotechnology	NOUN
can-1681	27	2	is	be	AUX
can-1681	27	3	widely	widely	ADV
can-1681	27	4	used	use	VERB
can-1681	27	5	in	in	ADP
can-1681	27	6	different	different	ADJ
can-1681	27	7	fields	field	NOUN
can-1681	27	8	.	.	PUNCT
can-1681	28	1	for	for	ADP
can-1681	28	2	example	example	NOUN
can-1681	28	3	,	,	PUNCT
can-1681	28	4	in	in	ADP
can-1681	28	5	the	the	DET
can-1681	28	6	field	field	NOUN
can-1681	28	7	of	of	ADP
can-1681	28	8	molecular	molecular	ADJ
can-1681	28	9	biology	biology	NOUN
can-1681	28	10	,	,	PUNCT
can-1681	28	11	the	the	DET
can-1681	28	12	biological	biological	ADJ
can-1681	28	13	detection	detection	NOUN
can-1681	28	14	method	method	NOUN
can-1681	28	15	of	of	ADP
can-1681	28	16	dna	dna	PROPN
can-1681	28	17	sequencing	sequencing	NOUN
can-1681	28	18	is	be	AUX
can-1681	28	19	developed	develop	VERB
can-1681	28	20	through	through	ADP
can-1681	28	21	a	a	DET
can-1681	28	22	nanopore	nanopore	ADJ
can-1681	28	23	sequencer[4,5	sequencer[4,5	NOUN
can-1681	28	24	]	]	PUNCT
can-1681	28	25	.	.	PUNCT
can-1681	29	1	in	in	ADP
can-1681	29	2	clinical	clinical	ADJ
can-1681	29	3	pharmacology	pharmacology	NOUN
can-1681	29	4	,	,	PUNCT
can-1681	29	5	it	it	PRON
can-1681	29	6	is	be	AUX
can-1681	29	7	used	use	VERB
can-1681	29	8	to	to	PART
can-1681	29	9	prepare	prepare	VERB
can-1681	29	10	nano	nano	NOUN
can-1681	29	11	drugs[6	drugs[6	ADP
can-1681	29	12	]	]	PUNCT
can-1681	29	13	.	.	PUNCT
can-1681	30	1	recently	recently	ADV
can-1681	30	2	,	,	PUNCT
can-1681	30	3	the	the	DET
can-1681	30	4	us	us	PROPN
can-1681	30	5	food	food	NOUN
can-1681	30	6	and	and	CCONJ
can-1681	30	7	drug	drug	PROPN
can-1681	30	8	administration	administration	NOUN
can-1681	30	9	approved	approve	VERB
can-1681	30	10	a	a	DET
can-1681	30	11	number	number	NOUN
can-1681	30	12	of	of	ADP
can-1681	30	13	nano	nano	NOUN
can-1681	30	14	drugs	drug	NOUN
can-1681	30	15	,	,	PUNCT
can-1681	30	16	including	include	VERB
can-1681	30	17	polymer	polymer	NOUN
can-1681	30	18	nano	nano	NOUN
can-1681	30	19	-	-	PUNCT
can-1681	30	20	particles	particle	NOUN
can-1681	30	21	,	,	PUNCT
can-1681	30	22	polymer	polymer	NOUN
can-1681	30	23	-	-	PUNCT
can-1681	30	24	drug	drug	NOUN
can-1681	30	25	conjugates	conjugate	NOUN
can-1681	30	26	,	,	PUNCT
can-1681	30	27	and	and	CCONJ
can-1681	30	28	degradable	degradable	ADJ
can-1681	30	29	polymer	polymer	NOUN
can-1681	30	30	structures	structure	NOUN
can-1681	30	31	classified	classify	VERB
can-1681	30	32	by	by	ADP
can-1681	30	33	material	material	NOUN
can-1681	30	34	type	type	NOUN
can-1681	30	35	.	.	PUNCT
can-1681	31	1	their	their	PRON
can-1681	31	2	function	function	NOUN
can-1681	31	3	is	be	AUX
can-1681	31	4	to	to	PART
can-1681	31	5	promote	promote	VERB
can-1681	31	6	the	the	DET
can-1681	31	7	diffusion	diffusion	NOUN
can-1681	31	8	of	of	ADP
can-1681	31	9	drugs	drug	NOUN
can-1681	31	10	through	through	ADP
can-1681	31	11	anatomical	anatomical	ADJ
can-1681	31	12	barriers	barrier	NOUN
can-1681	31	13	,	,	PUNCT
can-1681	31	14	improve	improve	VERB
can-1681	31	15	the	the	DET
can-1681	31	16	bioavailability	bioavailability	NOUN
can-1681	31	17	and	and	CCONJ
can-1681	31	18	half	half	ADJ
can-1681	31	19	-	-	PUNCT
can-1681	31	20	life	life	NOUN
can-1681	31	21	of	of	ADP
can-1681	31	22	drugs	drug	NOUN
can-1681	31	23	,	,	PUNCT
can-1681	31	24	and	and	CCONJ
can-1681	31	25	promote	promote	VERB
can-1681	31	26	the	the	DET
can-1681	31	27	controlled	control	VERB
can-1681	31	28	release	release	NOUN
can-1681	31	29	mechanism	mechanism	NOUN
can-1681	31	30	.	.	PUNCT
can-1681	32	1	it	it	PRON
can-1681	32	2	is	be	AUX
can-1681	32	3	also	also	ADV
can-1681	32	4	used	use	VERB
can-1681	32	5	to	to	PART
can-1681	32	6	optimize	optimize	VERB
can-1681	32	7	diagnostic	diagnostic	ADJ
can-1681	32	8	imaging	imaging	NOUN
can-1681	32	9	,	,	PUNCT
can-1681	32	10	using	use	VERB
can-1681	32	11	inorganic	inorganic	ADJ
can-1681	32	12	iron	iron	NOUN
can-1681	32	13	oxide	oxide	NOUN
can-1681	32	14	nanoparticles	nanoparticle	NOUN
can-1681	32	15	as	as	ADP
can-1681	32	16	a	a	DET
can-1681	32	17	reagent[7	reagent[7	NOUN
can-1681	32	18	]	]	PUNCT
can-1681	32	19	to	to	PART
can-1681	32	20	enhance	enhance	VERB
can-1681	32	21	image	image	NOUN
can-1681	32	22	contrast	contrast	NOUN
can-1681	32	23	.	.	PUNCT
can-1681	33	1	the	the	DET
can-1681	33	2	application	application	NOUN
can-1681	33	3	of	of	ADP
can-1681	33	4	nanotechnology	nanotechnology	NOUN
can-1681	33	5	in	in	ADP
can-1681	33	6	the	the	DET
can-1681	33	7	treatment	treatment	NOUN
can-1681	33	8	of	of	ADP
can-1681	33	9	eye	eye	NOUN
can-1681	33	10	diseases	disease	NOUN
can-1681	33	11	has	have	AUX
can-1681	33	12	become	become	VERB
can-1681	33	13	the	the	DET
can-1681	33	14	hope	hope	NOUN
can-1681	33	15	of	of	ADP
can-1681	33	16	millions	million	NOUN
can-1681	33	17	of	of	ADP
can-1681	33	18	patients	patient	NOUN
can-1681	33	19	with	with	ADP
can-1681	33	20	vision	vision	NOUN
can-1681	33	21	diseases	disease	NOUN
can-1681	33	22	.	.	PUNCT
can-1681	34	1	nano	nano	NOUN
can-1681	34	2	-	-	PUNCT
can-1681	34	3	carriers	carrier	NOUN
can-1681	34	4	and	and	CCONJ
can-1681	34	5	nano	nano	NOUN
can-1681	34	6	suspensions	suspension	NOUN
can-1681	34	7	react	react	VERB
can-1681	34	8	by	by	ADP
can-1681	34	9	releasing	release	VERB
can-1681	34	10	drugs	drug	NOUN
can-1681	34	11	at	at	ADP
can-1681	34	12	specific	specific	ADJ
can-1681	34	13	sites	site	NOUN
can-1681	34	14	,	,	PUNCT
can-1681	34	15	thereby	thereby	ADV
can-1681	34	16	reducing	reduce	VERB
can-1681	34	17	the	the	DET
can-1681	34	18	drug	drug	NOUN
can-1681	34	19	dose	dose	NOUN
can-1681	34	20	and	and	CCONJ
can-1681	34	21	minimizing	minimize	VERB
can-1681	34	22	the	the	DET
can-1681	34	23	risk	risk	NOUN
can-1681	34	24	of	of	ADP
can-1681	34	25	side	side	NOUN
can-1681	34	26	effects	effect	NOUN
can-1681	34	27	.	.	PUNCT
can-1681	35	1	for	for	ADP
can-1681	35	2	example	example	NOUN
can-1681	35	3	,	,	PUNCT
can-1681	35	4	brimonidine	brimonidine	NOUN
can-1681	35	5	,	,	PUNCT
can-1681	35	6	cyclosporine	cyclosporine	NOUN
can-1681	35	7	,	,	PUNCT
can-1681	35	8	corticosteroids	corticosteroid	NOUN
can-1681	35	9	,	,	PUNCT
can-1681	35	10	intravitreal	intravitreal	ADJ
can-1681	35	11	sustained	sustain	VERB
can-1681	35	12	-	-	PUNCT
can-1681	35	13	release	release	NOUN
can-1681	35	14	implants	implant	NOUN
can-1681	35	15	,	,	PUNCT
can-1681	35	16	etc	etc	X
can-1681	35	17	.	.	X
can-1681	35	18	in	in	ADP
can-1681	35	19	terms	term	NOUN
can-1681	35	20	of	of	ADP
can-1681	35	21	diagnosis	diagnosis	NOUN
can-1681	35	22	and	and	CCONJ
can-1681	35	23	follow	follow	VERB
can-1681	35	24	-	-	PUNCT
can-1681	35	25	up	up	NOUN
can-1681	35	26	,	,	PUNCT
can-1681	35	27	noninvasive	noninvasive	ADJ
can-1681	35	28	intraocular	intraocular	ADJ
can-1681	35	29	pressure	pressure	NOUN
can-1681	35	30	measurement	measurement	NOUN
can-1681	35	31	for	for	ADP
can-1681	35	32	detecting	detect	VERB
can-1681	35	33	high	high	ADJ
can-1681	35	34	intraocular	intraocular	ADJ
can-1681	35	35	pressure	pressure	NOUN
can-1681	35	36	and	and	CCONJ
can-1681	35	37	remote	remote	ADJ
can-1681	35	38	monitoring	monitoring	NOUN
can-1681	35	39	of	of	ADP
can-1681	35	40	nanodevices	nanodevice	NOUN
can-1681	35	41	will	will	AUX
can-1681	35	42	contribute	contribute	VERB
can-1681	35	43	to	to	ADP
can-1681	35	44	the	the	DET
can-1681	35	45	early	early	ADJ
can-1681	35	46	diagnosis	diagnosis	NOUN
can-1681	35	47	of	of	ADP
can-1681	35	48	progressive	progressive	ADJ
can-1681	35	49	optic	optic	ADJ
can-1681	35	50	atrophy	atrophy	NOUN
can-1681	35	51	and	and	CCONJ
can-1681	35	52	clinical	clinical	ADJ
can-1681	35	53	monitoring	monitoring	NOUN
can-1681	35	54	of	of	ADP
can-1681	35	55	patients	patient	NOUN
can-1681	35	56	with	with	ADP
can-1681	35	57	glaucomatous	glaucomatous	ADJ
can-1681	35	58	optic	optic	NOUN
can-1681	35	59	neuropathy[9,10	neuropathy[9,10	PRON
can-1681	35	60	]	]	PUNCT
can-1681	35	61	.	.	PUNCT
can-1681	36	1	in	in	ADP
can-1681	36	2	this	this	DET
can-1681	36	3	review	review	NOUN
can-1681	36	4	,	,	PUNCT
can-1681	36	5	we	we	PRON
can-1681	36	6	focus	focus	VERB
can-1681	36	7	on	on	ADP
can-1681	36	8	the	the	DET
can-1681	36	9	eye	eye	NOUN
can-1681	36	10	disease	disease	NOUN
can-1681	36	11	treatment	treatment	NOUN
can-1681	36	12	system	system	NOUN
can-1681	36	13	based	base	VERB
can-1681	36	14	on	on	ADP
can-1681	36	15	nanotechnology	nanotechnology	NOUN
can-1681	36	16	.	.	PUNCT
can-1681	37	1	firstly	firstly	ADV
can-1681	37	2	,	,	PUNCT
can-1681	37	3	the	the	DET
can-1681	37	4	anatomical	anatomical	ADJ
can-1681	37	5	structure	structure	NOUN
can-1681	37	6	of	of	ADP
can-1681	37	7	the	the	DET
can-1681	37	8	eye	eye	NOUN
can-1681	37	9	and	and	CCONJ
can-1681	37	10	the	the	DET
can-1681	37	11	obstacles	obstacle	NOUN
can-1681	37	12	to	to	ADP
can-1681	37	13	drug	drug	NOUN
can-1681	37	14	administration	administration	NOUN
can-1681	37	15	were	be	AUX
can-1681	37	16	briefly	briefly	ADV
can-1681	37	17	introduced	introduce	VERB
can-1681	37	18	.	.	PUNCT
can-1681	38	1	subsequently	subsequently	ADV
can-1681	38	2	,	,	PUNCT
can-1681	38	3	ophthalmic	ophthalmic	ADJ
can-1681	38	4	diseases	disease	NOUN
can-1681	38	5	and	and	CCONJ
can-1681	38	6	nano	nano	NOUN
can-1681	38	7	-	-	PUNCT
can-1681	38	8	systems	system	NOUN
can-1681	38	9	for	for	ADP
can-1681	38	10	the	the	DET
can-1681	38	11	treatment	treatment	NOUN
can-1681	38	12	of	of	ADP
can-1681	38	13	these	these	DET
can-1681	38	14	diseases	disease	NOUN
can-1681	38	15	are	be	AUX
can-1681	38	16	reviewed	review	VERB
can-1681	38	17	.	.	PUNCT
can-1681	39	1	finally	finally	ADV
can-1681	39	2	,	,	PUNCT
can-1681	39	3	the	the	DET
can-1681	39	4	application	application	NOUN
can-1681	39	5	prospects	prospect	NOUN
can-1681	39	6	and	and	CCONJ
can-1681	39	7	challenges	challenge	NOUN
can-1681	39	8	of	of	ADP
can-1681	39	9	nanotechnology	nanotechnology	NOUN
can-1681	39	10	in	in	ADP
can-1681	39	11	the	the	DET
can-1681	39	12	treatment	treatment	NOUN
can-1681	39	13	and	and	CCONJ
can-1681	39	14	diagnosis	diagnosis	NOUN
can-1681	39	15	of	of	ADP
can-1681	39	16	ophthalmic	ophthalmic	ADJ
can-1681	39	17	diseases	disease	NOUN
can-1681	39	18	are	be	AUX
can-1681	39	19	summarized	summarize	VERB
can-1681	39	20	.	.	PUNCT
can-1681	40	1	this	this	DET
can-1681	40	2	review	review	NOUN
can-1681	40	3	will	will	AUX
can-1681	40	4	provide	provide	VERB
can-1681	40	5	information	information	NOUN
can-1681	40	6	and	and	CCONJ
can-1681	40	7	new	new	ADJ
can-1681	40	8	ideas	idea	NOUN
can-1681	40	9	for	for	ADP
can-1681	40	10	the	the	DET
can-1681	40	11	implementation	implementation	NOUN
can-1681	40	12	of	of	ADP
can-1681	40	13	treatment	treatment	NOUN
can-1681	40	14	and	and	CCONJ
can-1681	40	15	the	the	DET
can-1681	40	16	development	development	NOUN
can-1681	40	17	of	of	ADP
can-1681	40	18	a	a	DET
can-1681	40	19	common	common	ADJ
can-1681	40	20	eye	eye	NOUN
can-1681	40	21	disease	disease	NOUN
can-1681	40	22	management	management	NOUN
can-1681	40	23	system	system	NOUN
can-1681	40	24	.	.	PUNCT
can-1681	41	1	2	2	X
can-1681	41	2	.	.	X
can-1681	41	3	ocular	ocular	ADJ
can-1681	41	4	anatomy	anatomy	NOUN
can-1681	41	5	and	and	CCONJ
can-1681	41	6	ocular	ocular	ADJ
can-1681	41	7	barrier	barrier	NOUN
can-1681	41	8	figure	figure	NOUN
can-1681	41	9	1	1	NUM
can-1681	41	10	shows	show	VERB
can-1681	41	11	nanotechnology	nanotechnology	NOUN
can-1681	41	12	delivers	deliver	VERB
can-1681	41	13	ophthalmic	ophthalmic	ADJ
can-1681	41	14	drugs	drug	NOUN
can-1681	41	15	through	through	ADP
can-1681	41	16	the	the	DET
can-1681	41	17	various	various	ADJ
can-1681	41	18	ocular	ocular	ADJ
can-1681	41	19	anatomical	anatomical	ADJ
can-1681	41	20	structures	structure	NOUN
can-1681	41	21	.	.	PUNCT
can-1681	42	1	table	table	NOUN
can-1681	42	2	1	1	NUM
can-1681	42	3	depicts	depict	VERB
can-1681	42	4	different	different	ADJ
can-1681	42	5	eye	eye	NOUN
can-1681	42	6	structures	structure	NOUN
can-1681	42	7	and	and	CCONJ
can-1681	42	8	possible	possible	ADJ
can-1681	42	9	therapeutic	therapeutic	ADJ
can-1681	42	10	targets	target	NOUN
can-1681	42	11	.	.	PUNCT
can-1681	43	1	its	its	PRON
can-1681	43	2	thickness	thickness	NOUN
can-1681	43	3	,	,	PUNCT
can-1681	43	4	function	function	NOUN
can-1681	43	5	,	,	PUNCT
can-1681	43	6	physiology	physiology	NOUN
can-1681	43	7	,	,	PUNCT
can-1681	43	8	and	and	CCONJ
can-1681	43	9	composition	composition	NOUN
can-1681	43	10	are	be	AUX
can-1681	43	11	emphatically	emphatically	ADV
can-1681	43	12	introduced	introduce	VERB
can-1681	43	13	.	.	PUNCT
can-1681	44	1	these	these	DET
can-1681	44	2	special	special	ADJ
can-1681	44	3	functions	function	NOUN
can-1681	44	4	can	can	AUX
can-1681	44	5	promote	promote	VERB
can-1681	44	6	or	or	CCONJ
can-1681	44	7	prevent	prevent	VERB
can-1681	44	8	the	the	DET
can-1681	44	9	effect	effect	NOUN
can-1681	44	10	of	of	ADP
can-1681	44	11	topical	topical	ADJ
can-1681	44	12	drugs	drug	NOUN
can-1681	44	13	.	.	PUNCT
can-1681	45	1	it	it	PRON
can-1681	45	2	also	also	ADV
can-1681	45	3	outlines	outline	VERB
can-1681	45	4	possible	possible	ADJ
can-1681	45	5	action	action	NOUN
can-1681	45	6	goals	goal	NOUN
can-1681	45	7	to	to	PART
can-1681	45	8	understand	understand	VERB
can-1681	45	9	the	the	DET
can-1681	45	10	progress	progress	NOUN
can-1681	45	11	of	of	ADP
can-1681	45	12	nanotechnology	nanotechnology	NOUN
can-1681	45	13	in	in	ADP
can-1681	45	14	ophthalmology	ophthalmology	NOUN
can-1681	45	15	.	.	PUNCT
can-1681	46	1	table	table	NOUN
can-1681	46	2	1	1	NUM
can-1681	46	3	.	.	PUNCT
can-1681	47	1	different	different	ADJ
can-1681	47	2	eye	eye	NOUN
can-1681	47	3	structures	structure	NOUN
can-1681	47	4	and	and	CCONJ
can-1681	47	5	possible	possible	ADJ
can-1681	47	6	therapeutic	therapeutic	ADJ
can-1681	47	7	targets	target	NOUN
can-1681	47	8	obstacle	obstacle	VERB
can-1681	47	9	barrier	barrier	NOUN
can-1681	47	10	thickness	thickness	NOUN
can-1681	47	11	function	function	NOUN
can-1681	47	12	physiology	physiology	NOUN
can-1681	47	13	constitution	constitution	NOUN
can-1681	47	14	other	other	ADJ
can-1681	47	15	components	component	NOUN
can-1681	47	16	tear	tear	ADJ
can-1681	47	17	film	film	NOUN
can-1681	47	18	3	3	NUM
can-1681	47	19	μm	μm	NOUN
can-1681	47	20	thick	thick	ADJ
can-1681	47	21	,	,	PUNCT
can-1681	47	22	3	3	NUM
can-1681	47	23	μl	μl	ADP
can-1681	47	24	volume[11	volume[11	NOUN
can-1681	47	25	]	]	X
can-1681	47	26	lubrication	lubrication	NOUN
can-1681	47	27	,	,	PUNCT
can-1681	47	28	debris	debris	NOUN
can-1681	47	29	removal	removal	NOUN
can-1681	47	30	,	,	PUNCT
can-1681	47	31	antibacterial	antibacterial	ADJ
can-1681	47	32	protection	protection	NOUN
can-1681	47	33	,	,	PUNCT
can-1681	47	34	stem	stem	NOUN
can-1681	47	35	cell	cell	NOUN
can-1681	47	36	nutrition	nutrition	NOUN
can-1681	47	37	,	,	PUNCT
can-1681	47	38	and	and	CCONJ
can-1681	47	39	corneal	corneal	ADJ
can-1681	47	40	transplantation	transplantation	NOUN
can-1681	47	41	maintenance	maintenance	NOUN
can-1681	47	42	;	;	PUNCT
can-1681	47	43	affect	affect	VERB
can-1681	47	44	the	the	DET
can-1681	47	45	refractive	refractive	ADJ
can-1681	47	46	index	index	NOUN
can-1681	47	47	of	of	ADP
can-1681	47	48	the	the	DET
can-1681	47	49	visual	visual	ADJ
can-1681	47	50	system[12	system[12	NOUN
can-1681	47	51	]	]	X
can-1681	47	52	.	.	PUNCT
can-1681	48	1	dynamic	dynamic	ADJ
can-1681	48	2	functional	functional	ADJ
can-1681	48	3	units	unit	NOUN
can-1681	48	4	:	:	PUNCT
can-1681	48	5	three	three	NUM
can-1681	48	6	chambers	chamber	NOUN
can-1681	48	7	(	(	PUNCT
can-1681	48	8	fornication	fornication	NOUN
can-1681	48	9	,	,	PUNCT
can-1681	48	10	lacrimal	lacrimal	ADJ
can-1681	48	11	meniscus	meniscus	NOUN
can-1681	48	12	,	,	PUNCT
can-1681	48	13	and	and	CCONJ
can-1681	48	14	anterior	anterior	ADJ
can-1681	48	15	lacrimal	lacrimal	ADJ
can-1681	48	16	membrane	membrane	NOUN
can-1681	48	17	)	)	PUNCT
can-1681	48	18	.	.	PUNCT
can-1681	49	1	surfactant	surfactant	NOUN
can-1681	49	2	and	and	CCONJ
can-1681	49	3	stability	stability	NOUN
can-1681	49	4	of	of	ADP
can-1681	49	5	tear	tear	ADJ
can-1681	49	6	film	film	NOUN
can-1681	49	7	lipid	lipid	NOUN
can-1681	49	8	component	component	NOUN
can-1681	49	9	,	,	PUNCT
can-1681	49	10	water	water	NOUN
can-1681	49	11	component	component	NOUN
can-1681	49	12	,	,	PUNCT
can-1681	49	13	and	and	CCONJ
can-1681	49	14	mucus	mucus	PROPN
can-1681	49	15	component[12	component[12	PROPN
can-1681	49	16	]	]	PUNCT
can-1681	49	17	.	.	PUNCT
can-1681	50	1	immunoglobulin	immunoglobulin	NOUN
can-1681	50	2	,	,	PUNCT
can-1681	50	3	lysozyme	lysozyme	NOUN
can-1681	50	4	,	,	PUNCT
can-1681	50	5	lactoferrin	lactoferrin	NOUN
can-1681	50	6	,	,	PUNCT
can-1681	50	7	oc	oc	NOUN
can-1681	50	8	,	,	PUNCT
can-1681	50	9	and	and	CCONJ
can-1681	50	10	β[14	β[14	PROPN
can-1681	50	11	]	]	PUNCT
can-1681	50	12	.	.	PUNCT
can-1681	51	1	corneal	corneal	ADJ
can-1681	51	2	540–600	540–600	NUM
can-1681	51	3	μm	μm	NOUN
can-1681	51	4	a	a	DET
can-1681	51	5	barrier	barrier	NOUN
can-1681	51	6	against	against	ADP
can-1681	51	7	infection	infection	NOUN
can-1681	51	8	and	and	CCONJ
can-1681	51	9	ocular	ocular	ADJ
can-1681	51	10	mechanical	mechanical	ADJ
can-1681	51	11	injury	injury	NOUN
can-1681	51	12	.	.	PUNCT
can-1681	52	1	two	two	NUM
can-1681	52	2	-	-	PUNCT
can-1681	52	3	thirds	third	NOUN
can-1681	52	4	of	of	ADP
can-1681	52	5	the	the	DET
can-1681	52	6	eye	eye	NOUN
can-1681	52	7	refraction	refraction	NOUN
can-1681	52	8	(	(	PUNCT
can-1681	52	9	image	image	NOUN
can-1681	52	10	perception)[15	perception)[15	NOUN
can-1681	52	11	]	]	PUNCT
can-1681	52	12	.	.	PUNCT
can-1681	53	1	corneal	corneal	ADJ
can-1681	53	2	epithelium	epithelium	NOUN
can-1681	53	3	:	:	PUNCT
can-1681	53	4	5–7	5–7	NUM
can-1681	53	5	layers	layer	NOUN
can-1681	53	6	of	of	ADP
can-1681	53	7	non	non	ADJ
can-1681	53	8	-	-	ADJ
can-1681	53	9	stratified	stratified	ADJ
can-1681	53	10	squamous	squamous	ADJ
can-1681	53	11	epithelium	epithelium	NOUN
can-1681	53	12	are	be	AUX
can-1681	53	13	connected	connect	VERB
can-1681	53	14	by	by	ADP
can-1681	53	15	desmosomes	desmosome	NOUN
can-1681	53	16	and	and	CCONJ
can-1681	53	17	connected	connect	VERB
can-1681	53	18	through	through	ADP
can-1681	53	19	gap	gap	NOUN
can-1681	53	20	junctions	junction	NOUN
can-1681	53	21	,	,	PUNCT
can-1681	53	22	allowing	allow	VERB
can-1681	53	23	the	the	DET
can-1681	53	24	diffusion	diffusion	NOUN
can-1681	53	25	of	of	ADP
can-1681	53	26	small	small	ADJ
can-1681	53	27	molecules	molecule	NOUN
can-1681	53	28	<	<	X
can-1681	53	29	1,000	1,000	NUM
can-1681	53	30	dalton	dalton	NOUN
can-1681	53	31	.	.	PUNCT
can-1681	54	1	it	it	PRON
can-1681	54	2	is	be	AUX
can-1681	54	3	in	in	ADP
can-1681	54	4	direct	direct	ADJ
can-1681	54	5	contact	contact	NOUN
can-1681	54	6	with	with	ADP
can-1681	54	7	aqueous	aqueous	ADJ
can-1681	54	8	humor	humor	NOUN
can-1681	54	9	through	through	ADP
can-1681	54	10	the	the	DET
can-1681	54	11	na+-k+-atpase	na+-k+-atpase	NOUN
can-1681	54	12	pump[16	pump[16	PROPN
can-1681	54	13	]	]	X
can-1681	55	1	present	present	ADJ
can-1681	55	2	in	in	ADP
can-1681	55	3	endothelial	endothelial	ADJ
can-1681	55	4	cells	cell	NOUN
can-1681	55	5	.	.	PUNCT
can-1681	56	1	avascular	avascular	ADJ
can-1681	56	2	lens	len	NOUN
can-1681	56	3	.	.	PUNCT
can-1681	57	1	viscoelastic	viscoelastic	ADJ
can-1681	57	2	structures	structure	NOUN
can-1681	57	3	are	be	AUX
can-1681	57	4	rich	rich	ADJ
can-1681	57	5	in	in	ADP
can-1681	57	6	glucosamine	glucosamine	NOUN
can-1681	57	7	and	and	CCONJ
can-1681	57	8	proteoglycans[17	proteoglycans[17	VERB
can-1681	57	9	]	]	PUNCT
can-1681	57	10	.	.	PUNCT
can-1681	58	1	sixth	sixth	ADJ
can-1681	58	2	floor	floor	NOUN
can-1681	58	3	:	:	PUNCT
can-1681	58	4	bowman	bowman	NOUN
can-1681	58	5	,	,	PUNCT
can-1681	58	6	stroma	stroma	PROPN
can-1681	58	7	,	,	PUNCT
can-1681	58	8	dua	dua	PROPN
can-1681	58	9	layer	layer	NOUN
can-1681	58	10	,	,	PUNCT
can-1681	58	11	descemet	descemet	NOUN
can-1681	58	12	,	,	PUNCT
can-1681	58	13	endothelial	endothelial	ADJ
can-1681	58	14	layer	layer	NOUN
can-1681	58	15	,	,	PUNCT
can-1681	58	16	corneal	corneal	ADJ
can-1681	58	17	epithelium	epithelium	NOUN
can-1681	58	18	.	.	PUNCT
can-1681	59	1	collagen	collagen	PROPN
can-1681	59	2	1	1	NUM
can-1681	59	3	,	,	PUNCT
can-1681	59	4	iii	iii	NOUN
can-1681	59	5	,	,	PUNCT
can-1681	59	6	v	v	NOUN
can-1681	59	7	and	and	CCONJ
can-1681	59	8	viii	viii	NOUN
can-1681	59	9	.	.	PUNCT
can-1681	60	1	proteoglycans	proteoglycans	PROPN
can-1681	60	2	(	(	PUNCT
can-1681	60	3	decorin	decorin	PROPN
can-1681	60	4	,	,	PUNCT
can-1681	60	5	lumican	lumican	NOUN
can-1681	60	6	,	,	PUNCT
can-1681	60	7	keratin	keratin	PROPN
can-1681	60	8	,	,	PUNCT
can-1681	60	9	mimecan	mimecan	NOUN
can-1681	60	10	,	,	PUNCT
can-1681	60	11	disaccharide	disaccharide	NOUN
can-1681	60	12	,	,	PUNCT
can-1681	60	13	and	and	CCONJ
can-1681	60	14	fibromodulin	fibromodulin	PROPN
can-1681	60	15	)	)	PUNCT
can-1681	60	16	and	and	CCONJ
can-1681	60	17	glycoproteins[15,17	glycoproteins[15,17	NOUN
can-1681	60	18	]	]	PUNCT
can-1681	60	19	.	.	PUNCT
can-1681	61	1	68	68	NUM
can-1681	61	2	table	table	NOUN
can-1681	61	3	1	1	NUM
can-1681	61	4	.	.	PUNCT
can-1681	61	5	(	(	PUNCT
can-1681	61	6	continued	continued	ADJ
can-1681	61	7	)	)	PUNCT
can-1681	61	8	obstacle	obstacle	NOUN
can-1681	61	9	barrier	barrier	NOUN
can-1681	61	10	thickness	thickness	NOUN
can-1681	61	11	function	function	NOUN
can-1681	61	12	physiology	physiology	NOUN
can-1681	61	13	constitution	constitution	NOUN
can-1681	61	14	other	other	ADJ
can-1681	61	15	components	component	NOUN
can-1681	61	16	conjunctival	conjunctival	VERB
can-1681	61	17	44.9	44.9	NUM
can-1681	61	18	±	±	NUM
can-1681	61	19	3.4	3.4	NUM
can-1681	61	20	μm	μm	NOUN
can-1681	61	21	through	through	ADP
can-1681	61	22	mucus	mucus	NOUN
can-1681	61	23	,	,	PUNCT
can-1681	61	24	it	it	PRON
can-1681	61	25	helps	help	VERB
can-1681	61	26	to	to	PART
can-1681	61	27	diffuse	diffuse	VERB
can-1681	61	28	the	the	DET
can-1681	61	29	tear	tear	ADJ
can-1681	61	30	film	film	NOUN
can-1681	61	31	,	,	PUNCT
can-1681	61	32	maintain	maintain	VERB
can-1681	61	33	the	the	DET
can-1681	61	34	stability	stability	NOUN
can-1681	61	35	of	of	ADP
can-1681	61	36	the	the	DET
can-1681	61	37	tear	tear	ADJ
can-1681	61	38	film	film	NOUN
can-1681	61	39	and	and	CCONJ
can-1681	61	40	prevent	prevent	VERB
can-1681	61	41	the	the	DET
can-1681	61	42	adhesion	adhesion	NOUN
can-1681	61	43	between	between	ADP
can-1681	61	44	infection	infection	NOUN
can-1681	61	45	and	and	CCONJ
can-1681	61	46	mucus[19	mucus[19	ADJ
can-1681	61	47	]	]	PUNCT
can-1681	61	48	.	.	PUNCT
can-1681	62	1	corneal	corneal	ADJ
can-1681	62	2	epithelial	epithelial	ADJ
can-1681	62	3	healing[20	healing[20	NOUN
can-1681	62	4	]	]	PUNCT
can-1681	62	5	.	.	PUNCT
can-1681	63	1	the	the	DET
can-1681	63	2	outermost	outermost	ADJ
can-1681	63	3	layer	layer	NOUN
can-1681	63	4	of	of	ADP
can-1681	63	5	the	the	DET
can-1681	63	6	eyeball	eyeball	NOUN
can-1681	63	7	.	.	PUNCT
can-1681	64	1	bulbar	bulbar	ADJ
can-1681	64	2	conjunctiva	conjunctiva	PROPN
can-1681	64	3	,	,	PUNCT
can-1681	64	4	eyelid	eyelid	NOUN
can-1681	64	5	,	,	PUNCT
can-1681	64	6	and	and	CCONJ
can-1681	64	7	forceps	forceps	NOUN
can-1681	64	8	.	.	PUNCT
can-1681	65	1	goblet	goblet	NOUN
can-1681	65	2	cells	cell	NOUN
can-1681	65	3	produce	produce	VERB
can-1681	65	4	mucin[21	mucin[21	NOUN
can-1681	65	5	]	]	PUNCT
can-1681	65	6	.	.	PUNCT
can-1681	66	1	multilayer	multilayer	PROPN
can-1681	66	2	non	non	PROPN
can-1681	66	3	keratinized	keratinized	ADJ
can-1681	66	4	columnar	columnar	ADJ
can-1681	66	5	epithelium	epithelium	NOUN
can-1681	66	6	(	(	PUNCT
can-1681	66	7	goblet	goblet	NOUN
can-1681	66	8	cells	cell	NOUN
can-1681	66	9	)	)	PUNCT
can-1681	66	10	in	in	ADP
can-1681	66	11	contact	contact	NOUN
can-1681	66	12	with	with	ADP
can-1681	66	13	lamina	lamina	PROPN
can-1681	66	14	propria	propria	PROPN
can-1681	66	15	(	(	PUNCT
can-1681	66	16	highly	highly	ADV
can-1681	66	17	vascularized	vascularized	ADJ
can-1681	66	18	connective	connective	ADJ
can-1681	66	19	tissue)[21	tissue)[21	NOUN
can-1681	66	20	]	]	PUNCT
can-1681	66	21	.	.	PUNCT
can-1681	67	1	tff1	tff1	PROPN
can-1681	67	2	and	and	CCONJ
can-1681	67	3	tff3	tff3	NOUN
can-1681	67	4	proteins	protein	NOUN
can-1681	67	5	are	be	AUX
can-1681	67	6	involved	involve	VERB
can-1681	67	7	in	in	ADP
can-1681	67	8	the	the	DET
can-1681	67	9	scarring	scarring	NOUN
can-1681	67	10	process	process	NOUN
can-1681	67	11	of	of	ADP
can-1681	67	12	corneal	corneal	ADJ
can-1681	67	13	tissue[19	tissue[19	NOUN
can-1681	67	14	]	]	PUNCT
can-1681	67	15	.	.	PUNCT
can-1681	68	1	scleral	scleral	ADJ
can-1681	68	2	0.53	0.53	NUM
can-1681	68	3	±	±	NUM
can-1681	68	4	0.14	0.14	NUM
can-1681	68	5	mm	mm	PROPN
can-1681	68	6	viscoelastic	viscoelastic	NOUN
can-1681	68	7	properties	property	NOUN
can-1681	68	8	give	give	VERB
can-1681	68	9	eye	eye	NOUN
can-1681	68	10	strength	strength	NOUN
can-1681	68	11	and	and	CCONJ
can-1681	68	12	resistance	resistance	NOUN
can-1681	68	13	when	when	SCONJ
can-1681	68	14	intraocular	intraocular	ADJ
can-1681	68	15	pressure	pressure	NOUN
can-1681	68	16	increases[14	increases[14	VERB
can-1681	68	17	]	]	PUNCT
can-1681	68	18	.	.	PUNCT
can-1681	69	1	the	the	DET
can-1681	69	2	matrix	matrix	NOUN
can-1681	69	3	is	be	AUX
can-1681	69	4	composed	compose	VERB
can-1681	69	5	of	of	ADP
can-1681	69	6	proteoglycan	proteoglycan	ADJ
can-1681	69	7	,	,	PUNCT
can-1681	69	8	elastin	elastin	NOUN
can-1681	69	9	,	,	PUNCT
can-1681	69	10	and	and	CCONJ
can-1681	69	11	large	large	ADJ
can-1681	69	12	collagen	collagen	NOUN
can-1681	69	13	fibers	fiber	NOUN
can-1681	69	14	.	.	PUNCT
can-1681	70	1	it	it	PRON
can-1681	70	2	is	be	AUX
can-1681	70	3	indirectly	indirectly	ADV
can-1681	70	4	nourished	nourish	VERB
can-1681	70	5	by	by	ADP
can-1681	70	6	the	the	DET
can-1681	70	7	sclera	sclera	NOUN
can-1681	70	8	and	and	CCONJ
can-1681	70	9	irrigated	irrigate	VERB
can-1681	70	10	by	by	ADP
can-1681	70	11	long	long	ADJ
can-1681	70	12	and	and	CCONJ
can-1681	70	13	short	short	ADJ
can-1681	70	14	posterior	posterior	ADJ
can-1681	70	15	ciliary	ciliary	ADJ
can-1681	70	16	vessels	vessel	NOUN
can-1681	70	17	and	and	CCONJ
can-1681	70	18	choroids	choroid	NOUN
can-1681	70	19	.	.	PUNCT
can-1681	71	1	venous	venous	ADJ
can-1681	71	2	drainage	drainage	NOUN
can-1681	71	3	occurs	occur	VERB
can-1681	71	4	in	in	ADP
can-1681	71	5	the	the	DET
can-1681	71	6	vortex	vortex	NOUN
can-1681	71	7	vein[22	vein[22	NOUN
can-1681	71	8	]	]	PUNCT
can-1681	71	9	.	.	PUNCT
can-1681	72	1	five	five	NUM
can-1681	72	2	-	-	PUNCT
can-1681	72	3	sixths	sixth	NOUN
can-1681	72	4	of	of	ADP
can-1681	72	5	the	the	DET
can-1681	72	6	eye	eye	NOUN
can-1681	72	7	robe	robe	NOUN
can-1681	72	8	.	.	PUNCT
can-1681	73	1	the	the	DET
can-1681	73	2	innermost	innermost	ADJ
can-1681	73	3	layer	layer	NOUN
can-1681	73	4	(	(	PUNCT
can-1681	73	5	lá	lá	PROPN
can-1681	73	6	mina	mina	PROPN
can-1681	73	7	fusca)[14	fusca)[14	PROPN
can-1681	73	8	]	]	PUNCT
can-1681	73	9	.	.	PUNCT
can-1681	74	1	use	use	VERB
can-1681	74	2	iris	iris	NOUN
can-1681	74	3	and	and	CCONJ
can-1681	74	4	ciliary	ciliary	ADJ
can-1681	74	5	bod	bod	ADJ
can-1681	74	6	y	y	NOUN
can-1681	74	7	:	:	PUNCT
can-1681	74	8	1–2	1–2	NUM
can-1681	74	9	mm	mm	NUM
can-1681	74	10	iris	iris	NOUN
can-1681	74	11	,	,	PUNCT
can-1681	74	12	light	light	ADJ
can-1681	74	13	input	input	NOUN
can-1681	74	14	regulator	regulator	NOUN
can-1681	74	15	.	.	PUNCT
can-1681	75	1	ciliary	ciliary	ADJ
can-1681	75	2	body	body	NOUN
can-1681	75	3	:	:	PUNCT
can-1681	75	4	regulates	regulate	VERB
can-1681	75	5	,	,	PUNCT
can-1681	75	6	produces	produce	VERB
can-1681	75	7	(	(	PUNCT
can-1681	75	8	apigenin	apigenin	ADJ
can-1681	75	9	)	)	PUNCT
can-1681	75	10	and	and	CCONJ
can-1681	75	11	regulates	regulate	VERB
can-1681	75	12	(	(	PUNCT
can-1681	75	13	electrochemical	electrochemical	ADJ
can-1681	75	14	gradient	gradient	NOUN
can-1681	75	15	)	)	PUNCT
can-1681	75	16	aqueous	aqueous	ADJ
can-1681	75	17	humor	humor	NOUN
can-1681	75	18	flow	flow	NOUN
can-1681	75	19	and	and	CCONJ
can-1681	75	20	secretes	secrete	NOUN
can-1681	75	21	hyaluronic	hyaluronic	ADJ
can-1681	75	22	acid	acid	NOUN
can-1681	75	23	to	to	ADP
can-1681	75	24	the	the	DET
can-1681	75	25	vitreous	vitreous	ADJ
can-1681	75	26	.	.	PUNCT
can-1681	76	1	aqueous	aqueous	ADJ
can-1681	76	2	humor	humor	NOUN
can-1681	76	3	:	:	PUNCT
can-1681	76	4	nutrition	nutrition	NOUN
can-1681	76	5	of	of	ADP
can-1681	76	6	avascular	avascular	ADJ
can-1681	76	7	ocular	ocular	ADJ
can-1681	76	8	structure	structure	NOUN
can-1681	76	9	,	,	PUNCT
can-1681	76	10	homeostasis	homeostasis	NOUN
can-1681	76	11	of	of	ADP
can-1681	76	12	ocular	ocular	ADJ
can-1681	76	13	tissue	tissue	NOUN
can-1681	76	14	,	,	PUNCT
can-1681	76	15	clearance	clearance	NOUN
can-1681	76	16	of	of	ADP
can-1681	76	17	metabolites	metabolite	NOUN
can-1681	76	18	,	,	PUNCT
can-1681	76	19	transport	transport	NOUN
can-1681	76	20	of	of	ADP
can-1681	76	21	neurotransmitters	neurotransmitter	NOUN
can-1681	76	22	,	,	PUNCT
can-1681	76	23	and	and	CCONJ
can-1681	76	24	stability	stability	NOUN
can-1681	76	25	of	of	ADP
can-1681	76	26	ocular	ocular	ADJ
can-1681	76	27	structure[23	structure[23	NOUN
can-1681	76	28	]	]	PUNCT
can-1681	76	29	.	.	PUNCT
can-1681	77	1	ciliary	ciliary	ADJ
can-1681	77	2	body	body	NOUN
can-1681	77	3	cornea	cornea	NOUN
can-1681	77	4	scleral	scleral	ADJ
can-1681	77	5	junction	junction	NOUN
can-1681	77	6	(	(	PUNCT
can-1681	77	7	iris	iris	NOUN
can-1681	77	8	angle	angle	NOUN
can-1681	77	9	):	):	PUNCT
can-1681	77	10	the	the	DET
can-1681	77	11	space	space	NOUN
can-1681	77	12	where	where	SCONJ
can-1681	77	13	aqueous	aqueous	ADJ
can-1681	77	14	humor	humor	NOUN
can-1681	77	15	flows	flow	VERB
can-1681	77	16	from	from	ADP
can-1681	77	17	the	the	DET
can-1681	77	18	posterior	posterior	ADJ
can-1681	77	19	chamber	chamber	NOUN
can-1681	77	20	to	to	ADP
can-1681	77	21	the	the	DET
can-1681	77	22	anterior	anterior	ADJ
can-1681	77	23	chamber	chamber	PROPN
can-1681	77	24	.	.	PUNCT
can-1681	78	1	aqueous	aqueous	ADJ
can-1681	78	2	humor	humor	NOUN
can-1681	78	3	contributes	contribute	VERB
can-1681	78	4	to	to	ADP
can-1681	78	5	the	the	DET
can-1681	78	6	circulation	circulation	NOUN
can-1681	78	7	of	of	ADP
can-1681	78	8	inflammatory	inflammatory	ADJ
can-1681	78	9	cells	cell	NOUN
can-1681	78	10	and	and	CCONJ
can-1681	78	11	mediators	mediator	NOUN
can-1681	78	12	under	under	ADP
can-1681	78	13	pathological	pathological	ADJ
can-1681	78	14	conditions	condition	NOUN
can-1681	78	15	and	and	CCONJ
can-1681	78	16	the	the	DET
can-1681	78	17	diffusion	diffusion	NOUN
can-1681	78	18	of	of	ADP
can-1681	78	19	drugs	drug	NOUN
can-1681	78	20	to	to	ADP
can-1681	78	21	different	different	ADJ
can-1681	78	22	tissues[24	tissues[24	NOUN
can-1681	78	23	]	]	PUNCT
can-1681	78	24	.	.	PUNCT
can-1681	79	1	the	the	DET
can-1681	79	2	middle	middle	ADJ
can-1681	79	3	part	part	NOUN
can-1681	79	4	of	of	ADP
can-1681	79	5	the	the	DET
can-1681	79	6	eyeball	eyeball	NOUN
can-1681	79	7	is	be	AUX
can-1681	79	8	composed	compose	VERB
can-1681	79	9	of	of	ADP
can-1681	79	10	the	the	DET
can-1681	79	11	iris	iris	NOUN
can-1681	79	12	,	,	PUNCT
can-1681	79	13	ciliary	ciliary	ADJ
can-1681	79	14	,	,	PUNCT
can-1681	79	15	body	body	NOUN
can-1681	79	16	,	,	PUNCT
can-1681	79	17	and	and	CCONJ
can-1681	79	18	choroid	choroid	NOUN
can-1681	79	19	.	.	PUNCT
can-1681	80	1	iris	iris	NOUN
can-1681	80	2	(	(	PUNCT
can-1681	80	3	three	three	NUM
can-1681	80	4	layers	layer	NOUN
can-1681	80	5	):	):	PUNCT
can-1681	80	6	posterior	posterior	ADJ
can-1681	80	7	iris	iris	NOUN
can-1681	80	8	(	(	PUNCT
can-1681	80	9	pigment	pigment	NOUN
can-1681	80	10	epithelium	epithelium	NOUN
can-1681	80	11	)	)	PUNCT
can-1681	80	12	,	,	PUNCT
can-1681	80	13	anterior	anterior	ADJ
can-1681	80	14	iris	iris	NOUN
can-1681	80	15	muscle	muscle	NOUN
can-1681	80	16	(	(	PUNCT
can-1681	80	17	round	round	ADJ
can-1681	80	18	or	or	CCONJ
can-1681	80	19	contractile	contractile	NOUN
can-1681	80	20	,	,	PUNCT
can-1681	80	21	radial	radial	ADJ
can-1681	80	22	or	or	CCONJ
can-1681	80	23	dilator	dilator	NOUN
can-1681	80	24	of	of	ADP
can-1681	80	25	the	the	DET
can-1681	80	26	pupil	pupil	NOUN
can-1681	80	27	)	)	PUNCT
can-1681	80	28	,	,	PUNCT
can-1681	80	29	and	and	CCONJ
can-1681	80	30	matrix	matrix	NOUN
can-1681	80	31	(	(	PUNCT
can-1681	80	32	vascularized	vascularized	ADJ
can-1681	80	33	connective	connective	ADJ
can-1681	80	34	tissue	tissue	NOUN
can-1681	80	35	)	)	PUNCT
can-1681	80	36	.	.	PUNCT
can-1681	81	1	the	the	DET
can-1681	81	2	ciliary	ciliary	ADJ
can-1681	81	3	body	body	NOUN
can-1681	81	4	(	(	PUNCT
can-1681	81	5	flat	flat	ADJ
can-1681	81	6	part	part	NOUN
can-1681	81	7	and	and	CCONJ
can-1681	81	8	fold	fold	ADJ
can-1681	81	9	part)[24	part)[24	NOUN
can-1681	81	10	]	]	PUNCT
can-1681	81	11	.	.	PUNCT
can-1681	82	1	aqueous	aqueous	ADJ
can-1681	82	2	humor	humor	NOUN
can-1681	82	3	consists	consist	VERB
can-1681	82	4	of	of	ADP
can-1681	82	5	organic	organic	ADJ
can-1681	82	6	and	and	CCONJ
can-1681	82	7	inorganic	inorganic	ADJ
can-1681	82	8	ions	ion	NOUN
can-1681	82	9	,	,	PUNCT
can-1681	82	10	carbohydrates	carbohydrate	NOUN
can-1681	82	11	,	,	PUNCT
can-1681	82	12	glutathione	glutathione	NOUN
can-1681	82	13	,	,	PUNCT
can-1681	82	14	urea	urea	NOUN
can-1681	82	15	,	,	PUNCT
can-1681	82	16	amino	amino	NOUN
can-1681	82	17	acids	acid	NOUN
can-1681	82	18	,	,	PUNCT
can-1681	82	19	proteins	protein	NOUN
can-1681	82	20	(	(	PUNCT
can-1681	82	21	collagenase	collagenase	NOUN
can-1681	82	22	,	,	PUNCT
can-1681	82	23	immunoglobulin	immunoglobulin	NOUN
can-1681	82	24	)	)	PUNCT
can-1681	82	25	,	,	PUNCT
can-1681	82	26	oxygen	oxygen	NOUN
can-1681	82	27	,	,	PUNCT
can-1681	82	28	carbon	carbon	NOUN
can-1681	82	29	dioxide	dioxide	NOUN
can-1681	82	30	,	,	PUNCT
can-1681	82	31	and	and	CCONJ
can-1681	82	32	water[23	water[23	PROPN
can-1681	82	33	]	]	X
can-1681	82	34	.	.	PUNCT
can-1681	83	1	crystalline	crystalline	PROPN
can-1681	83	2	3.5–5	3.5–5	NUM
can-1681	83	3	mm	mm	PROPN
can-1681	83	4	reflex	reflex	NOUN
can-1681	83	5	power	power	NOUN
can-1681	83	6	(	(	PUNCT
can-1681	83	7	20	20	NUM
can-1681	83	8	%	%	NOUN
can-1681	83	9	of	of	ADP
can-1681	83	10	the	the	DET
can-1681	83	11	total	total	ADJ
can-1681	83	12	eyeball	eyeball	NOUN
can-1681	83	13	)	)	PUNCT
can-1681	83	14	.	.	PUNCT
can-1681	84	1	an	an	DET
can-1681	84	2	image	image	NOUN
can-1681	84	3	focused	focus	VERB
can-1681	84	4	on	on	ADP
can-1681	84	5	the	the	DET
can-1681	84	6	outside	outside	NOUN
can-1681	84	7	of	of	ADP
can-1681	84	8	the	the	DET
can-1681	84	9	retina	retina	NOUN
can-1681	84	10	.	.	PUNCT
can-1681	85	1	enzyme	enzyme	NOUN
can-1681	85	2	-	-	PUNCT
can-1681	85	3	mediated	mediate	VERB
can-1681	85	4	oxidant	oxidant	ADJ
can-1681	85	5	defense	defense	NOUN
can-1681	85	6	mechanisms	mechanism	NOUN
can-1681	85	7	(	(	PUNCT
can-1681	85	8	glutathione	glutathione	NOUN
can-1681	85	9	reductase	reductase	NOUN
can-1681	85	10	and	and	CCONJ
can-1681	85	11	catalase)[25	catalase)[25	NOUN
can-1681	85	12	]	]	PUNCT
can-1681	85	13	.	.	PUNCT
can-1681	86	1	it	it	PRON
can-1681	86	2	is	be	AUX
can-1681	86	3	nourished	nourish	VERB
can-1681	86	4	by	by	ADP
can-1681	86	5	aqueous	aqueous	ADJ
can-1681	86	6	humor	humor	NOUN
can-1681	86	7	.	.	PUNCT
can-1681	87	1	metabolic	metabolic	NOUN
can-1681	87	2	activity	activity	NOUN
can-1681	87	3	is	be	AUX
can-1681	87	4	involved	involve	VERB
can-1681	87	5	in	in	ADP
can-1681	87	6	ion	ion	NOUN
can-1681	87	7	exchange	exchange	NOUN
can-1681	87	8	through	through	ADP
can-1681	87	9	sodium	sodium	NOUN
can-1681	87	10	,	,	PUNCT
can-1681	87	11	potassium	potassium	NOUN
can-1681	87	12	,	,	PUNCT
can-1681	87	13	calcium	calcium	NOUN
can-1681	87	14	,	,	PUNCT
can-1681	87	15	and	and	CCONJ
can-1681	87	16	chloride	chloride	NOUN
can-1681	87	17	channels	channel	NOUN
can-1681	87	18	,	,	PUNCT
can-1681	87	19	as	as	ADV
can-1681	87	20	well	well	ADV
can-1681	87	21	as	as	ADP
can-1681	87	22	glucose	glucose	NOUN
can-1681	87	23	,	,	PUNCT
can-1681	87	24	amino	amino	NOUN
can-1681	87	25	acids	acid	NOUN
can-1681	87	26	,	,	PUNCT
can-1681	87	27	and	and	CCONJ
can-1681	87	28	antioxidants	antioxidant	NOUN
can-1681	87	29	(	(	PUNCT
can-1681	87	30	glutathione	glutathione	NOUN
can-1681	87	31	)	)	PUNCT
can-1681	88	1	[	[	X
can-1681	88	2	26	26	NUM
can-1681	88	3	]	]	PUNCT
can-1681	88	4	.	.	PUNCT
can-1681	89	1	no	no	DET
can-1681	89	2	vascular	vascular	ADJ
can-1681	89	3	structure	structure	NOUN
can-1681	89	4	,	,	PUNCT
can-1681	89	5	transparent	transparent	ADJ
can-1681	89	6	.	.	PUNCT
can-1681	90	1	it	it	PRON
can-1681	90	2	is	be	AUX
can-1681	90	3	divided	divide	VERB
can-1681	90	4	into	into	ADP
can-1681	90	5	the	the	DET
can-1681	90	6	capsule	capsule	NOUN
can-1681	90	7	,	,	PUNCT
can-1681	90	8	crystalline	crystalline	NOUN
can-1681	90	9	epithelium	epithelium	NOUN
can-1681	90	10	,	,	PUNCT
can-1681	90	11	cortex	cortex	NOUN
can-1681	90	12	,	,	PUNCT
can-1681	90	13	and	and	CCONJ
can-1681	90	14	nucleus	nucleus	NOUN
can-1681	90	15	.	.	PUNCT
can-1681	91	1	60	60	NUM
can-1681	91	2	%	%	NOUN
can-1681	91	3	protein	protein	NOUN
can-1681	91	4	(	(	PUNCT
can-1681	91	5	crystalline	crystalline	NOUN
can-1681	91	6	α	α	NOUN
can-1681	91	7	,	,	PUNCT
can-1681	91	8	β	β	X
can-1681	91	9	,	,	PUNCT
can-1681	91	10	γ	γ	NOUN
can-1681	91	11	)	)	PUNCT
can-1681	91	12	.	.	PUNCT
can-1681	92	1	it	it	PRON
can-1681	92	2	is	be	AUX
can-1681	92	3	surrounded	surround	VERB
can-1681	92	4	by	by	ADP
can-1681	92	5	collagen	collagen	NOUN
can-1681	92	6	capsules	capsule	NOUN
can-1681	92	7	(	(	PUNCT
can-1681	92	8	mainly	mainly	ADV
can-1681	92	9	type	type	NOUN
can-1681	92	10	iv	iv	ADP
can-1681	92	11	and	and	CCONJ
can-1681	92	12	xviii	xviii	NOUN
can-1681	92	13	)	)	PUNCT
can-1681	92	14	and	and	CCONJ
can-1681	92	15	laminin	laminin	NOUN
can-1681	92	16	,	,	PUNCT
can-1681	92	17	entactin	entactin	ADJ
can-1681	92	18	,	,	PUNCT
can-1681	92	19	proteoglycan	proteoglycan	ADJ
can-1681	92	20	(	(	PUNCT
can-1681	92	21	heparan	heparan	ADJ
can-1681	92	22	sulfate	sulfate	NOUN
can-1681	92	23	)	)	PUNCT
can-1681	92	24	,	,	PUNCT
can-1681	92	25	pearl	pearl	NOUN
can-1681	92	26	,	,	PUNCT
can-1681	92	27	and	and	CCONJ
can-1681	92	28	fibronectin	fibronectin	NOUN
can-1681	92	29	.	.	PUNCT
can-1681	93	1	in	in	ADP
can-1681	93	2	the	the	DET
can-1681	93	3	banded	banded	ADJ
can-1681	93	4	region	region	NOUN
can-1681	93	5	,	,	PUNCT
can-1681	93	6	the	the	DET
can-1681	93	7	main	main	ADJ
can-1681	93	8	components	component	NOUN
can-1681	93	9	are	be	AUX
can-1681	93	10	fibrin	fibrin	NOUN
can-1681	93	11	and	and	CCONJ
can-1681	93	12	elastin[25,26	elastin[25,26	NOUN
can-1681	93	13	]	]	PUNCT
can-1681	93	14	.	.	PUNCT
can-1681	94	1	membrane	membrane	NOUN
can-1681	94	2	proteins	protein	NOUN
can-1681	94	3	(	(	PUNCT
can-1681	94	4	different	different	ADJ
can-1681	94	5	cell	cell	NOUN
can-1681	94	6	connections	connection	NOUN
can-1681	94	7	of	of	ADP
can-1681	94	8	lens	lens	NOUN
can-1681	94	9	epithelial	epithelial	ADJ
can-1681	94	10	cells	cell	NOUN
can-1681	94	11	):	):	PUNCT
can-1681	94	12	cadherin	cadherin	NOUN
can-1681	94	13	,	,	PUNCT
can-1681	94	14	calmodulin	calmodulin	NOUN
can-1681	94	15	,	,	PUNCT
can-1681	94	16	type	type	NOUN
can-1681	94	17	ii	ii	NOUN
can-1681	94	18	neural	neural	ADJ
can-1681	94	19	adhesion	adhesion	NOUN
can-1681	94	20	molecule	molecule	NOUN
can-1681	94	21	,	,	PUNCT
can-1681	94	22	endogenous	endogenous	ADJ
can-1681	94	23	major	major	ADJ
can-1681	94	24	protein	protein	NOUN
can-1681	94	25	(	(	PUNCT
can-1681	94	26	hydrophobic	hydrophobic	NOUN
can-1681	94	27	)	)	PUNCT
can-1681	94	28	,	,	PUNCT
can-1681	94	29	and	and	CCONJ
can-1681	94	30	apigenin	apigenin	ADJ
can-1681	94	31	0	0	NUM
can-1681	94	32	enzyme	enzyme	NOUN
can-1681	94	33	(	(	PUNCT
can-1681	94	34	glyceraldehyde	glyceraldehyde	NOUN
can-1681	94	35	3	3	NUM
can-1681	94	36	phosphate	phosphate	NOUN
can-1681	94	37	dehydrogenase	dehydrogenase	NOUN
can-1681	94	38	)	)	PUNCT
can-1681	94	39	.	.	PUNCT
can-1681	95	1	the	the	DET
can-1681	95	2	cytoskeleton	cytoskeleton	NOUN
can-1681	95	3	includes	include	VERB
can-1681	95	4	actin	actin	NOUN
can-1681	95	5	,	,	PUNCT
can-1681	95	6	α	α	NOUN
can-1681	95	7	-	-	PUNCT
can-1681	95	8	actin	actin	NOUN
can-1681	95	9	,	,	PUNCT
can-1681	95	10	anquirina	anquirina	NOUN
can-1681	95	11	,	,	PUNCT
can-1681	95	12	trompomudulina	trompomudulina	NOUN
can-1681	95	13	,	,	PUNCT
can-1681	95	14	myosin	myosin	PROPN
can-1681	95	15	,	,	PUNCT
can-1681	95	16	and	and	CCONJ
can-1681	95	17	spectria[25,26	spectria[25,26	PROPN
can-1681	95	18	]	]	PUNCT
can-1681	95	19	.	.	PUNCT
can-1681	96	1	69	69	NUM
can-1681	96	2	table	table	NOUN
can-1681	96	3	1	1	NUM
can-1681	96	4	.	.	PUNCT
can-1681	97	1	(	(	PUNCT
can-1681	97	2	continued	continued	ADJ
can-1681	97	3	)	)	PUNCT
can-1681	97	4	obstacle	obstacle	NOUN
can-1681	97	5	barrier	barrier	NOUN
can-1681	97	6	thickness	thickness	NOUN
can-1681	97	7	obstacle	obstacle	NOUN
can-1681	97	8	barrier	barrier	NOUN
can-1681	97	9	thickness	thickness	NOUN
can-1681	97	10	obstacle	obstacle	NOUN
can-1681	97	11	barrier	barrier	NOUN
can-1681	97	12	thickness	thickness	NOUN
can-1681	97	13	choroid	choroid	NOUN
can-1681	97	14	220–350	220–350	NUM
can-1681	97	15	μm	μm	NUM
can-1681	97	16	flush	flush	ADJ
can-1681	97	17	the	the	DET
can-1681	97	18	retina	retina	NOUN
can-1681	97	19	and	and	CCONJ
can-1681	97	20	replenish	replenish	VERB
can-1681	97	21	oxygen	oxygen	NOUN
can-1681	97	22	and	and	CCONJ
can-1681	97	23	nutrition	nutrition	NOUN
can-1681	97	24	.	.	PUNCT
can-1681	98	1	absorb	absorb	VERB
can-1681	98	2	light	light	NOUN
can-1681	98	3	,	,	PUNCT
can-1681	98	4	regulate	regulate	VERB
can-1681	98	5	body	body	NOUN
can-1681	98	6	temperature	temperature	NOUN
can-1681	98	7	,	,	PUNCT
can-1681	98	8	and	and	CCONJ
can-1681	98	9	adjust	adjust	VERB
can-1681	98	10	intraocular	intraocular	ADJ
can-1681	98	11	pressure	pressure	NOUN
can-1681	98	12	by	by	ADP
can-1681	98	13	controlling	control	VERB
can-1681	98	14	blood	blood	NOUN
can-1681	98	15	flow[27	flow[27	NOUN
can-1681	98	16	]	]	PUNCT
can-1681	98	17	.	.	PUNCT
can-1681	99	1	drainage	drainage	NOUN
can-1681	99	2	of	of	ADP
can-1681	99	3	aqueous	aqueous	ADJ
can-1681	99	4	humor	humor	NOUN
can-1681	99	5	from	from	ADP
can-1681	99	6	the	the	DET
can-1681	99	7	anterior	anterior	ADJ
can-1681	99	8	chamber	chamber	NOUN
can-1681	99	9	through	through	ADP
can-1681	99	10	the	the	DET
can-1681	99	11	uveoscleral	uveoscleral	ADJ
can-1681	99	12	pathway	pathway	NOUN
can-1681	99	13	(	(	PUNCT
can-1681	99	14	accounting	account	VERB
can-1681	99	15	for	for	ADP
can-1681	99	16	35	35	NUM
can-1681	99	17	%	%	NOUN
can-1681	99	18	of	of	ADP
can-1681	99	19	its	its	PRON
can-1681	99	20	drainage	drainage	NOUN
can-1681	99	21	volume)[27	volume)[27	NOUN
can-1681	99	22	]	]	PUNCT
can-1681	99	23	.	.	PUNCT
can-1681	100	1	blood	blood	NOUN
can-1681	100	2	vessels	vessel	NOUN
can-1681	100	3	,	,	PUNCT
can-1681	100	4	melanocytes	melanocyte	NOUN
can-1681	100	5	,	,	PUNCT
can-1681	100	6	fibroblasts	fibroblast	NOUN
can-1681	100	7	,	,	PUNCT
can-1681	100	8	immunocompetent	immunocompetent	ADJ
can-1681	100	9	cells	cell	NOUN
can-1681	100	10	,	,	PUNCT
can-1681	100	11	and	and	CCONJ
can-1681	100	12	supporting	support	VERB
can-1681	100	13	structures	structure	NOUN
can-1681	100	14	(	(	PUNCT
can-1681	100	15	collagen	collagen	NOUN
can-1681	100	16	and	and	CCONJ
can-1681	100	17	elastic	elastic	ADJ
can-1681	100	18	connective	connective	ADJ
can-1681	100	19	tissue	tissue	NOUN
can-1681	100	20	)	)	PUNCT
can-1681	100	21	.	.	PUNCT
can-1681	101	1	four	four	NUM
can-1681	101	2	layers	layer	NOUN
can-1681	101	3	:	:	PUNCT
can-1681	101	4	chorion	chorion	NOUN
can-1681	101	5	,	,	PUNCT
can-1681	101	6	chorionic	chorionic	ADJ
can-1681	101	7	column	column	NOUN
can-1681	101	8	,	,	PUNCT
can-1681	101	9	two	two	NUM
can-1681	101	10	layers	layer	NOUN
can-1681	101	11	of	of	ADP
can-1681	101	12	blood	blood	NOUN
can-1681	101	13	vessels	vessel	NOUN
can-1681	101	14	,	,	PUNCT
can-1681	101	15	and	and	CCONJ
can-1681	101	16	suprachoroidal[27	suprachoroidal[27	PROPN
can-1681	101	17	]	]	PUNCT
can-1681	101	18	.	.	PUNCT
can-1681	102	1	vitreous	vitreous	ADJ
can-1681	102	2	humor	humor	NOUN
can-1681	102	3	4	4	NUM
can-1681	102	4	cc	cc	NOUN
can-1681	102	5	its	its	PRON
can-1681	102	6	transparency	transparency	NOUN
can-1681	102	7	allows	allow	VERB
can-1681	102	8	light	light	NOUN
can-1681	102	9	to	to	PART
can-1681	102	10	pass	pass	VERB
can-1681	102	11	through	through	ADP
can-1681	102	12	the	the	DET
can-1681	102	13	retina	retina	NOUN
can-1681	102	14	and	and	CCONJ
can-1681	102	15	gives	give	VERB
can-1681	102	16	the	the	DET
can-1681	102	17	eye	eye	NOUN
can-1681	102	18	structure	structure	NOUN
can-1681	102	19	.	.	PUNCT
can-1681	103	1	due	due	ADP
can-1681	103	2	to	to	ADP
can-1681	103	3	its	its	PRON
can-1681	103	4	physicochemical	physicochemical	ADJ
can-1681	103	5	properties	property	NOUN
can-1681	103	6	and	and	CCONJ
can-1681	103	7	ionic	ionic	ADJ
can-1681	103	8	charge	charge	NOUN
can-1681	103	9	,	,	PUNCT
can-1681	103	10	it	it	PRON
can-1681	103	11	poses	pose	VERB
can-1681	103	12	obstacles	obstacle	NOUN
can-1681	103	13	and	and	CCONJ
can-1681	103	14	challenges	challenge	NOUN
can-1681	103	15	to	to	ADP
can-1681	103	16	drugs	drug	NOUN
can-1681	103	17	working	work	VERB
can-1681	103	18	at	at	ADP
can-1681	103	19	the	the	DET
can-1681	103	20	posterior	posterior	ADJ
can-1681	103	21	pole	pole	NOUN
can-1681	103	22	level[28	level[28	PROPN
can-1681	103	23	]	]	PUNCT
can-1681	103	24	.	.	PUNCT
can-1681	104	1	the	the	DET
can-1681	104	2	viscoelastic	viscoelastic	ADJ
can-1681	104	3	gel	gel	NOUN
can-1681	104	4	is	be	AUX
can-1681	104	5	located	locate	VERB
can-1681	104	6	between	between	ADP
can-1681	104	7	the	the	DET
can-1681	104	8	lens	lens	NOUN
can-1681	104	9	and	and	CCONJ
can-1681	104	10	retina	retina	VERB
can-1681	104	11	.	.	PUNCT
can-1681	105	1	it	it	PRON
can-1681	105	2	contains	contain	VERB
can-1681	105	3	water	water	NOUN
can-1681	105	4	(	(	PUNCT
can-1681	105	5	98	98	NUM
can-1681	105	6	%	%	NOUN
can-1681	105	7	)	)	PUNCT
can-1681	105	8	,	,	PUNCT
can-1681	105	9	collagen	collagen	NOUN
can-1681	105	10	fibers	fiber	NOUN
can-1681	105	11	(	(	PUNCT
can-1681	105	12	ii	ii	NOUN
can-1681	105	13	,	,	PUNCT
can-1681	105	14	v	v	PROPN
can-1681	105	15	,	,	PUNCT
can-1681	105	16	ix	ix	ADV
can-1681	105	17	,	,	PUNCT
can-1681	105	18	and	and	CCONJ
can-1681	105	19	xi	xi	NUM
can-1681	105	20	)	)	PUNCT
can-1681	105	21	,	,	PUNCT
can-1681	105	22	polyurealic	polyurealic	NOUN
can-1681	105	23	acid	acid	NOUN
can-1681	105	24	,	,	PUNCT
can-1681	105	25	electrolyte	electrolyte	NOUN
can-1681	105	26	(	(	PUNCT
can-1681	105	27	sodium	sodium	NOUN
can-1681	105	28	,	,	PUNCT
can-1681	105	29	potassium	potassium	NOUN
can-1681	105	30	,	,	PUNCT
can-1681	105	31	calcium	calcium	NOUN
can-1681	105	32	,	,	PUNCT
can-1681	105	33	and	and	CCONJ
can-1681	105	34	chlorine	chlorine	NOUN
can-1681	105	35	)	)	PUNCT
can-1681	105	36	,	,	PUNCT
can-1681	105	37	prealbumin	prealbumin	NOUN
can-1681	105	38	,	,	PUNCT
can-1681	105	39	and	and	CCONJ
can-1681	105	40	transfer	transfer	VERB
can-1681	105	41	protein	protein	NOUN
can-1681	105	42	.	.	PUNCT
can-1681	106	1	equivalent	equivalent	ADJ
can-1681	106	2	to	to	ADP
can-1681	106	3	80	80	NUM
can-1681	106	4	%	%	NOUN
can-1681	106	5	(	(	PUNCT
can-1681	106	6	4	4	NUM
can-1681	106	7	cc	cc	NOUN
can-1681	106	8	)	)	PUNCT
can-1681	106	9	of	of	ADP
can-1681	106	10	eye	eye	NOUN
can-1681	106	11	volume[29.30	volume[29.30	PROPN
can-1681	106	12	]	]	PUNCT
can-1681	106	13	.	.	PUNCT
can-1681	107	1	more	more	ADJ
can-1681	107	2	than	than	ADP
can-1681	107	3	1,205	1,205	NUM
can-1681	107	4	proteins[30	proteins[30	NOUN
can-1681	107	5	]	]	PUNCT
can-1681	107	6	.	.	PUNCT
can-1681	108	1	retinal	retinal	ADJ
can-1681	108	2	pigment	pigment	NOUN
can-1681	108	3	epithelium	epithelium	NOUN
can-1681	108	4	0.4–1	0.4–1	NOUN
can-1681	108	5	mm[31	mm[31	X
can-1681	108	6	]	]	X
can-1681	108	7	the	the	DET
can-1681	108	8	light	light	ADJ
can-1681	108	9	energy	energy	NOUN
can-1681	108	10	gathered	gather	VERB
can-1681	108	11	at	at	ADP
can-1681	108	12	the	the	DET
can-1681	108	13	macula	macula	NOUN
can-1681	108	14	is	be	AUX
can-1681	108	15	absorbed	absorb	VERB
can-1681	108	16	through	through	ADP
can-1681	108	17	the	the	DET
can-1681	108	18	ocular	ocular	ADJ
can-1681	108	19	refraction	refraction	NOUN
can-1681	108	20	system	system	NOUN
can-1681	108	21	(	(	PUNCT
can-1681	108	22	cornea	cornea	NOUN
can-1681	108	23	and	and	CCONJ
can-1681	108	24	lens	len	NOUN
can-1681	108	25	)	)	PUNCT
can-1681	108	26	to	to	PART
can-1681	108	27	improve	improve	VERB
can-1681	108	28	the	the	DET
can-1681	108	29	visual	visual	ADJ
can-1681	108	30	quality	quality	NOUN
can-1681	108	31	.	.	PUNCT
can-1681	109	1	the	the	DET
can-1681	109	2	cell	cell	NOUN
can-1681	109	3	’s	’s	PART
can-1681	109	4	own	own	ADJ
can-1681	109	5	dna	dna	PROPN
can-1681	109	6	repair	repair	NOUN
can-1681	109	7	mechanism	mechanism	NOUN
can-1681	109	8	includes	include	VERB
can-1681	109	9	the	the	DET
can-1681	109	10	defense	defense	NOUN
can-1681	109	11	mechanism	mechanism	NOUN
can-1681	109	12	against	against	ADP
can-1681	109	13	reactive	reactive	ADJ
can-1681	109	14	oxygen	oxygen	NOUN
can-1681	109	15	species[33	species[33	NOUN
can-1681	109	16	]	]	PUNCT
can-1681	109	17	.	.	PUNCT
can-1681	110	1	high	high	ADJ
can-1681	110	2	infusion	infusion	NOUN
can-1681	110	3	of	of	ADP
can-1681	110	4	chorionic	chorionic	ADJ
can-1681	110	5	gonadotropin	gonadotropin	NOUN
can-1681	110	6	(	(	PUNCT
can-1681	110	7	1400	1400	NUM
can-1681	110	8	cc	cc	NOUN
can-1681	110	9	/	/	SYM
can-1681	110	10	min/100	min/100	PROPN
can-1681	110	11	g	g	PROPN
can-1681	110	12	tissue)[34	tissue)[34	PROPN
can-1681	110	13	]	]	PUNCT
can-1681	110	14	.	.	PUNCT
can-1681	111	1	antioxidants	antioxidant	NOUN
can-1681	111	2	:	:	PUNCT
can-1681	111	3	superoxide	superoxide	NOUN
can-1681	111	4	dismutase	dismutase	NOUN
can-1681	111	5	and	and	CCONJ
can-1681	111	6	catalase	catalase	NOUN
can-1681	111	7	.	.	PUNCT
can-1681	112	1	retinal	retinal	ADJ
can-1681	112	2	pigment	pigment	NOUN
can-1681	112	3	epithelium	epithelium	NOUN
can-1681	112	4	0.4–1	0.4–1	NOUN
can-1681	112	5	mm[31	mm[31	X
can-1681	112	6	]	]	X
can-1681	112	7	through	through	ADP
can-1681	112	8	the	the	DET
can-1681	112	9	melanin	melanin	NOUN
can-1681	112	10	in	in	ADP
can-1681	112	11	epr	epr	PROPN
can-1681	112	12	melanosomes	melanosomes	PROPN
can-1681	112	13	,	,	PUNCT
can-1681	112	14	carotenoids	carotenoid	NOUN
can-1681	112	15	(	(	PUNCT
can-1681	112	16	lutein	lutein	NOUN
can-1681	112	17	and	and	CCONJ
can-1681	112	18	zeaxanthin	zeaxanthin	PROPN
can-1681	112	19	)	)	PUNCT
can-1681	112	20	,	,	PUNCT
can-1681	112	21	and	and	CCONJ
can-1681	112	22	ascorbic	ascorbic	NOUN
can-1681	112	23	acid	acid	NOUN
can-1681	112	24	in	in	ADP
can-1681	112	25	light	light	ADJ
can-1681	112	26	receptors	receptor	NOUN
can-1681	112	27	,	,	PUNCT
can-1681	112	28	photooxidation	photooxidation	NOUN
can-1681	112	29	,	,	PUNCT
can-1681	112	30	and	and	CCONJ
can-1681	112	31	oxidative	oxidative	ADJ
can-1681	112	32	damage	damage	NOUN
can-1681	112	33	are	be	AUX
can-1681	112	34	prevented	prevent	VERB
can-1681	112	35	through	through	ADP
can-1681	112	36	the	the	DET
can-1681	112	37	light	light	ADJ
can-1681	112	38	absorption	absorption	NOUN
can-1681	112	39	mechanism[32	mechanism[32	NOUN
can-1681	112	40	]	]	PUNCT
can-1681	112	41	.	.	PUNCT
can-1681	113	1	it	it	PRON
can-1681	113	2	transports	transport	VERB
can-1681	113	3	ions	ion	NOUN
can-1681	113	4	and	and	CCONJ
can-1681	113	5	water	water	NOUN
can-1681	113	6	from	from	ADP
can-1681	113	7	subretinal	subretinal	ADJ
can-1681	113	8	space	space	NOUN
can-1681	113	9	to	to	ADP
can-1681	113	10	chorionic	chorionic	ADJ
can-1681	113	11	capillaries	capillary	NOUN
can-1681	113	12	through	through	ADP
can-1681	113	13	the	the	DET
can-1681	113	14	na+-k+-atpase	na+-k+-atpase	NOUN
can-1681	113	15	pump	pump	NOUN
can-1681	113	16	and	and	CCONJ
can-1681	113	17	k+/cl	k+/cl	VERB
can-1681	113	18	transporter	transporter	NOUN
can-1681	113	19	and	and	CCONJ
can-1681	113	20	maintains	maintain	VERB
can-1681	113	21	intraocular	intraocular	ADJ
can-1681	113	22	pressure	pressure	NOUN
can-1681	113	23	to	to	ADP
can-1681	113	24	a	a	DET
can-1681	113	25	certain	certain	ADJ
can-1681	113	26	extent[33,35	extent[33,35	NOUN
can-1681	113	27	]	]	X
can-1681	113	28	the	the	DET
can-1681	113	29	maintenance	maintenance	NOUN
can-1681	113	30	of	of	ADP
can-1681	113	31	intracellular	intracellular	ADJ
can-1681	113	32	ph	ph	NOUN
can-1681	113	33	is	be	AUX
can-1681	113	34	mediated	mediate	VERB
can-1681	113	35	by	by	ADP
can-1681	113	36	the	the	DET
can-1681	113	37	chloride	chloride	NOUN
can-1681	113	38	bicarbonate	bicarbonate	NOUN
can-1681	113	39	exchanger	exchanger	NOUN
can-1681	113	40	on	on	ADP
can-1681	113	41	the	the	DET
can-1681	113	42	basement	basement	NOUN
can-1681	113	43	lateral	lateral	ADJ
can-1681	113	44	membrane	membrane	NOUN
can-1681	113	45	of	of	ADP
can-1681	113	46	epr[33	epr[33	NOUN
can-1681	113	47	]	]	PUNCT
can-1681	113	48	.	.	PUNCT
can-1681	114	1	retinal	retinal	ADJ
can-1681	114	2	nerve	nerve	NOUN
can-1681	114	3	sensation	sensation	NOUN
can-1681	114	4	light	light	ADJ
can-1681	114	5	transduction	transduction	NOUN
can-1681	114	6	of	of	ADP
can-1681	114	7	external	external	ADJ
can-1681	114	8	images[36	images[36	NOUN
can-1681	114	9	]	]	PUNCT
can-1681	114	10	.	.	PUNCT
can-1681	115	1	it	it	PRON
can-1681	115	2	is	be	AUX
can-1681	115	3	perfused	perfuse	VERB
can-1681	115	4	by	by	ADP
can-1681	115	5	the	the	DET
can-1681	115	6	central	central	ADJ
can-1681	115	7	retinal	retinal	ADJ
can-1681	115	8	artery	artery	NOUN
can-1681	115	9	and	and	CCONJ
can-1681	115	10	receives	receive	VERB
can-1681	115	11	metabolic	metabolic	NOUN
can-1681	115	12	input	input	NOUN
can-1681	115	13	through	through	ADP
can-1681	115	14	the	the	DET
can-1681	115	15	choroid[31	choroid[31	PROPN
can-1681	115	16	]	]	X
can-1681	115	17	.	.	PUNCT
can-1681	116	1	the	the	DET
can-1681	116	2	self	self	NOUN
can-1681	116	3	-	-	PUNCT
can-1681	116	4	regulation	regulation	NOUN
can-1681	116	5	of	of	ADP
can-1681	116	6	retinal	retinal	ADJ
can-1681	116	7	pressure	pressure	NOUN
can-1681	116	8	is	be	AUX
can-1681	116	9	mainly	mainly	ADV
can-1681	116	10	mediated	mediate	VERB
can-1681	116	11	by	by	ADP
can-1681	116	12	the	the	DET
can-1681	116	13	increase	increase	NOUN
can-1681	116	14	in	in	ADP
can-1681	116	15	retinal	retinal	ADJ
can-1681	116	16	vascular	vascular	NOUN
can-1681	116	17	resistance[37	resistance[37	NOUN
can-1681	116	18	]	]	PUNCT
can-1681	116	19	.	.	PUNCT
can-1681	117	1	the	the	DET
can-1681	117	2	outer	outer	ADJ
can-1681	117	3	membrane	membrane	NOUN
can-1681	117	4	(	(	PUNCT
can-1681	117	5	photoreceptor	photoreceptor	NOUN
can-1681	117	6	and	and	CCONJ
can-1681	117	7	muller	muller	NOUN
can-1681	117	8	cell	cell	PROPN
can-1681	117	9	)	)	PUNCT
can-1681	117	10	,	,	PUNCT
can-1681	117	11	outer	outer	ADJ
can-1681	117	12	nuclear	nuclear	ADJ
can-1681	117	13	layer	layer	NOUN
can-1681	117	14	(	(	PUNCT
can-1681	117	15	photoreceptor	photoreceptor	NOUN
can-1681	117	16	nucleus	nucleus	NOUN
can-1681	117	17	)	)	PUNCT
can-1681	117	18	,	,	PUNCT
can-1681	117	19	outer	outer	ADJ
can-1681	117	20	plexiform	plexiform	NOUN
can-1681	117	21	layer	layer	NOUN
can-1681	117	22	(	(	PUNCT
can-1681	117	23	photoreceptor	photoreceptor	NOUN
can-1681	117	24	axon	axon	NOUN
can-1681	117	25	)	)	PUNCT
can-1681	117	26	,	,	PUNCT
can-1681	117	27	inner	inner	ADJ
can-1681	117	28	nuclear	nuclear	ADJ
can-1681	117	29	layer	layer	NOUN
can-1681	117	30	(	(	PUNCT
can-1681	117	31	bipolar	bipolar	ADJ
can-1681	117	32	cell	cell	NOUN
can-1681	117	33	)	)	PUNCT
can-1681	117	34	,	,	PUNCT
can-1681	117	35	inner	inner	ADJ
can-1681	117	36	plexiform	plexiform	NOUN
can-1681	117	37	layer	layer	NOUN
can-1681	117	38	(	(	PUNCT
can-1681	117	39	bipolar	bipolar	ADJ
can-1681	117	40	cell	cell	NOUN
can-1681	117	41	and	and	CCONJ
can-1681	117	42	amacrine	amacrine	NOUN
can-1681	117	43	cell	cell	NOUN
can-1681	117	44	)	)	PUNCT
can-1681	117	45	,	,	PUNCT
can-1681	117	46	ganglion	ganglion	NOUN
can-1681	117	47	cell	cell	NOUN
can-1681	117	48	layer	layer	NOUN
can-1681	117	49	,	,	PUNCT
can-1681	117	50	nerve	nerve	NOUN
can-1681	117	51	fiber	fiber	NOUN
can-1681	117	52	layer	layer	NOUN
can-1681	117	53	,	,	PUNCT
can-1681	117	54	inner	inner	ADJ
can-1681	117	55	limiting	limit	VERB
can-1681	117	56	membrane	membrane	NOUN
can-1681	117	57	(	(	PUNCT
can-1681	117	58	basement	basement	NOUN
can-1681	117	59	membrane	membrane	NOUN
can-1681	117	60	formed	form	VERB
can-1681	117	61	by	by	ADP
can-1681	117	62	muller	muller	PROPN
can-1681	117	63	cell	cell	PROPN
can-1681	117	64	extension)[31,36	extension)[31,36	PROPN
can-1681	117	65	]	]	PUNCT
can-1681	117	66	.	.	PUNCT
can-1681	118	1	70	70	NUM
can-1681	118	2	figure	figure	NOUN
can-1681	118	3	1	1	NUM
can-1681	118	4	.	.	PUNCT
can-1681	118	5	nanotechnology	nanotechnology	NOUN
can-1681	118	6	delivers	deliver	VERB
can-1681	118	7	ophthalmic	ophthalmic	ADJ
can-1681	118	8	drugs	drug	NOUN
can-1681	118	9	through	through	ADP
can-1681	118	10	different	different	ADJ
can-1681	118	11	ocular	ocular	ADJ
can-1681	118	12	anatomical	anatomical	ADJ
can-1681	118	13	structures	structure	NOUN
can-1681	118	14	.	.	PUNCT
can-1681	119	1	np	np	X
can-1681	119	2	:	:	PUNCT
can-1681	119	3	nanoparticles	nanoparticle	NOUN
can-1681	119	4	.	.	PUNCT
can-1681	120	1	3	3	X
can-1681	120	2	.	.	X
can-1681	120	3	nanotechnology	nanotechnology	PROPN
can-1681	120	4	concept	concept	NOUN
can-1681	120	5	nanotechnology	nanotechnology	PROPN
can-1681	120	6	is	be	AUX
can-1681	120	7	a	a	DET
can-1681	120	8	discipline	discipline	NOUN
can-1681	120	9	that	that	PRON
can-1681	120	10	studies	study	NOUN
can-1681	120	11	,	,	PUNCT
can-1681	120	12	designs	design	NOUN
can-1681	120	13	,	,	PUNCT
can-1681	120	14	synthesizes	synthesize	NOUN
can-1681	120	15	,	,	PUNCT
can-1681	120	16	operates	operate	NOUN
can-1681	120	17	,	,	PUNCT
can-1681	120	18	and	and	CCONJ
can-1681	120	19	applies	apply	VERB
can-1681	120	20	functional	functional	ADJ
can-1681	120	21	materials	material	NOUN
can-1681	120	22	,	,	PUNCT
can-1681	120	23	equipment	equipment	NOUN
can-1681	120	24	,	,	PUNCT
can-1681	120	25	and	and	CCONJ
can-1681	120	26	systems	system	NOUN
can-1681	120	27	by	by	ADP
can-1681	120	28	controlling	control	VERB
can-1681	120	29	nanomaterials	nanomaterial	NOUN
can-1681	120	30	(	(	PUNCT
can-1681	120	31	1–100	1–100	NUM
can-1681	120	32	nm	nm	NOUN
can-1681	120	33	)	)	PUNCT
can-1681	120	34	.	.	PUNCT
can-1681	121	1	the	the	DET
can-1681	121	2	application	application	NOUN
can-1681	121	3	of	of	ADP
can-1681	121	4	nanotechnology	nanotechnology	NOUN
can-1681	121	5	in	in	ADP
can-1681	121	6	the	the	DET
can-1681	121	7	diagnosis	diagnosis	NOUN
can-1681	121	8	,	,	PUNCT
can-1681	121	9	treatment	treatment	NOUN
can-1681	121	10	,	,	PUNCT
can-1681	121	11	and	and	CCONJ
can-1681	121	12	control	control	NOUN
can-1681	121	13	of	of	ADP
can-1681	121	14	various	various	ADJ
can-1681	121	15	diseases	disease	NOUN
can-1681	121	16	is	be	AUX
can-1681	121	17	being	be	AUX
can-1681	121	18	implemented	implement	VERB
can-1681	121	19	rapidly	rapidly	ADV
can-1681	121	20	.	.	PUNCT
can-1681	122	1	this	this	DET
can-1681	122	2	new	new	ADJ
can-1681	122	3	branch	branch	NOUN
can-1681	122	4	of	of	ADP
can-1681	122	5	science	science	NOUN
can-1681	122	6	is	be	AUX
can-1681	122	7	called	call	VERB
can-1681	122	8	nanomedicine	nanomedicine	ADJ
can-1681	122	9	.	.	PUNCT
can-1681	123	1	with	with	ADP
can-1681	123	2	the	the	DET
can-1681	123	3	advancement	advancement	NOUN
can-1681	123	4	of	of	ADP
can-1681	123	5	nanotechnology	nanotechnology	NOUN
can-1681	123	6	in	in	ADP
can-1681	123	7	medicine	medicine	NOUN
can-1681	123	8	and	and	CCONJ
can-1681	123	9	surgery	surgery	NOUN
can-1681	123	10	,	,	PUNCT
can-1681	123	11	its	its	PRON
can-1681	123	12	application	application	NOUN
can-1681	123	13	in	in	ADP
can-1681	123	14	ophthalmology	ophthalmology	NOUN
can-1681	123	15	has	have	AUX
can-1681	123	16	made	make	VERB
can-1681	123	17	progress	progress	NOUN
can-1681	123	18	.	.	PUNCT
can-1681	124	1	therefore	therefore	ADV
can-1681	124	2	,	,	PUNCT
can-1681	124	3	new	new	ADJ
can-1681	124	4	eye	eye	NOUN
can-1681	124	5	nano	nano	NOUN
can-1681	124	6	-	-	PUNCT
can-1681	124	7	systems	system	NOUN
can-1681	124	8	with	with	ADP
can-1681	124	9	different	different	ADJ
can-1681	124	10	shapes	shape	NOUN
can-1681	124	11	and	and	CCONJ
can-1681	124	12	characteristics	characteristic	NOUN
can-1681	124	13	to	to	PART
can-1681	124	14	optimize	optimize	VERB
can-1681	124	15	the	the	DET
can-1681	124	16	bioavailability	bioavailability	NOUN
can-1681	124	17	of	of	ADP
can-1681	124	18	drugs	drug	NOUN
can-1681	124	19	,	,	PUNCT
can-1681	124	20	prolong	prolong	VERB
can-1681	124	21	the	the	DET
can-1681	124	22	contact	contact	NOUN
can-1681	124	23	time	time	NOUN
can-1681	124	24	and	and	CCONJ
can-1681	124	25	reduce	reduce	VERB
can-1681	124	26	the	the	DET
can-1681	124	27	eye	eye	NOUN
can-1681	124	28	removal	removal	NOUN
can-1681	124	29	process	process	NOUN
can-1681	124	30	had	have	AUX
can-1681	124	31	been	be	AUX
can-1681	124	32	designed[39	designed[39	PROPN
can-1681	124	33	]	]	PUNCT
can-1681	124	34	.	.	PUNCT
can-1681	125	1	there	there	PRON
can-1681	125	2	are	be	VERB
can-1681	125	3	many	many	ADJ
can-1681	125	4	nano	nano	NOUN
can-1681	125	5	-	-	PUNCT
can-1681	125	6	systems	system	NOUN
can-1681	125	7	that	that	PRON
can-1681	125	8	have	have	AUX
can-1681	125	9	been	be	AUX
can-1681	125	10	applied	apply	VERB
can-1681	125	11	in	in	ADP
can-1681	125	12	the	the	DET
can-1681	125	13	treatment	treatment	NOUN
can-1681	125	14	of	of	ADP
can-1681	125	15	different	different	ADJ
can-1681	125	16	eye	eye	NOUN
can-1681	125	17	diseases	disease	NOUN
can-1681	125	18	.	.	PUNCT
can-1681	126	1	nanoparticle	nanoparticle	NOUN
can-1681	126	2	-	-	PUNCT
can-1681	126	3	filled	fill	VERB
can-1681	126	4	contact	contact	NOUN
can-1681	126	5	lenses	lense	NOUN
can-1681	126	6	with	with	ADP
can-1681	126	7	acetazolamide	acetazolamide	NOUN
can-1681	126	8	for	for	ADP
can-1681	126	9	the	the	DET
can-1681	126	10	treatment	treatment	NOUN
can-1681	126	11	of	of	ADP
can-1681	126	12	glaucoma[40	glaucoma[40	NOUN
can-1681	126	13	]	]	PUNCT
can-1681	126	14	,	,	PUNCT
can-1681	126	15	biodegradable	biodegradable	ADJ
can-1681	126	16	subconjunctival	subconjunctival	NOUN
can-1681	126	17	implants	implant	NOUN
can-1681	126	18	for	for	ADP
can-1681	126	19	the	the	DET
can-1681	126	20	treatment	treatment	NOUN
can-1681	126	21	of	of	ADP
can-1681	126	22	xerophthalmia	xerophthalmia	NOUN
can-1681	127	1	[	[	X
can-1681	127	2	41,42	41,42	NOUN
can-1681	127	3	]	]	PUNCT
can-1681	127	4	,	,	PUNCT
can-1681	127	5	the	the	DET
can-1681	127	6	development	development	NOUN
can-1681	127	7	of	of	ADP
can-1681	127	8	diclofenac	diclofenac	ADJ
can-1681	127	9	eye	eye	NOUN
can-1681	127	10	release	release	NOUN
can-1681	127	11	nano	nano	NOUN
can-1681	127	12	colloid	colloid	NOUN
can-1681	127	13	system	system	NOUN
can-1681	127	14	based	base	VERB
can-1681	127	15	on	on	ADP
can-1681	127	16	hydrogel[43,44	hydrogel[43,44	PROPN
can-1681	127	17	]	]	PUNCT
can-1681	127	18	,	,	PUNCT
can-1681	127	19	polymer	polymer	NOUN
can-1681	127	20	nano	nano	NOUN
can-1681	127	21	colloid	colloid	NOUN
can-1681	127	22	system	system	NOUN
can-1681	127	23	for	for	ADP
can-1681	127	24	inflammatory	inflammatory	ADJ
can-1681	127	25	diseases[45,46	diseases[45,46	PROPN
can-1681	127	26	]	]	X
can-1681	127	27	,	,	PUNCT
can-1681	127	28	and	and	CCONJ
can-1681	127	29	nanostructured	nanostructure	VERB
can-1681	127	30	lipid	lipid	NOUN
can-1681	127	31	transporters	transporter	NOUN
can-1681	127	32	for	for	ADP
can-1681	127	33	controlling	control	VERB
can-1681	127	34	drug	drug	NOUN
can-1681	127	35	delivery	delivery	NOUN
can-1681	127	36	in	in	ADP
can-1681	127	37	ocular	ocular	ADJ
can-1681	127	38	infections[47,48	infections[47,48	NOUN
can-1681	127	39	]	]	PUNCT
can-1681	127	40	.	.	PUNCT
can-1681	128	1	3.1	3.1	NUM
can-1681	128	2	liposome	liposome	NOUN
can-1681	128	3	liposomes	liposome	NOUN
can-1681	128	4	are	be	AUX
can-1681	128	5	lipid	lipid	ADJ
can-1681	128	6	vesicles	vesicle	NOUN
can-1681	128	7	comprising	comprise	VERB
can-1681	128	8	one	one	NUM
can-1681	128	9	or	or	CCONJ
can-1681	128	10	more	more	ADJ
can-1681	128	11	phospholipid	phospholipid	NOUN
can-1681	128	12	double	double	ADJ
can-1681	128	13	chains	chain	NOUN
can-1681	128	14	that	that	PRON
can-1681	128	15	surround	surround	VERB
can-1681	128	16	an	an	DET
can-1681	128	17	aqueous	aqueous	ADJ
can-1681	128	18	core	core	NOUN
can-1681	128	19	.	.	PUNCT
can-1681	129	1	according	accord	VERB
can-1681	129	2	to	to	ADP
can-1681	129	3	the	the	DET
can-1681	129	4	size	size	NOUN
can-1681	129	5	of	of	ADP
can-1681	129	6	liposomes	liposome	NOUN
can-1681	129	7	and	and	CCONJ
can-1681	129	8	the	the	DET
can-1681	129	9	number	number	NOUN
can-1681	129	10	of	of	ADP
can-1681	129	11	phospholipid	phospholipid	NOUN
can-1681	129	12	double	double	ADJ
can-1681	129	13	chains	chain	NOUN
can-1681	129	14	,	,	PUNCT
can-1681	129	15	liposomes	liposome	NOUN
can-1681	129	16	can	can	AUX
can-1681	129	17	be	be	AUX
can-1681	129	18	divided	divide	VERB
can-1681	129	19	into	into	ADP
can-1681	129	20	small	small	ADJ
can-1681	129	21	monolayer	monolayer	NOUN
can-1681	129	22	vesicles	vesicle	NOUN
can-1681	129	23	(	(	PUNCT
can-1681	129	24	10	10	NUM
can-1681	129	25	and	and	CCONJ
can-1681	129	26	100	100	NUM
can-1681	129	27	nm	nm	NOUN
can-1681	129	28	)	)	PUNCT
can-1681	129	29	,	,	PUNCT
can-1681	129	30	and	and	CCONJ
can-1681	129	31	large	large	ADJ
can-1681	129	32	monolayer	monolayer	NOUN
can-1681	129	33	vesicles	vesicle	NOUN
can-1681	129	34	(	(	PUNCT
can-1681	129	35	100	100	NUM
can-1681	129	36	and	and	CCONJ
can-1681	129	37	300	300	NUM
can-1681	129	38	nm	nm	NOUN
can-1681	129	39	)	)	PUNCT
can-1681	129	40	and	and	CCONJ
can-1681	129	41	multi	multi	ADJ
can-1681	129	42	membrane	membrane	PROPN
can-1681	129	43	vesicles[49	vesicles[49	PROPN
can-1681	129	44	]	]	PUNCT
can-1681	129	45	containing	contain	VERB
can-1681	129	46	more	more	ADJ
can-1681	129	47	than	than	ADP
can-1681	129	48	one	one	NUM
can-1681	129	49	phospholipid	phospholipid	NOUN
can-1681	129	50	double	double	ADJ
can-1681	129	51	chain	chain	NOUN
can-1681	129	52	.	.	PUNCT
can-1681	130	1	liposomes	liposome	NOUN
can-1681	130	2	are	be	AUX
can-1681	130	3	ideal	ideal	ADJ
can-1681	130	4	because	because	SCONJ
can-1681	130	5	they	they	PRON
can-1681	130	6	encapsulate	encapsulate	VERB
can-1681	130	7	both	both	CCONJ
can-1681	130	8	hydrophilic	hydrophilic	ADJ
can-1681	130	9	and	and	CCONJ
can-1681	130	10	hydrophobic	hydrophobic	NOUN
can-1681	130	11	drugs	drug	NOUN
can-1681	130	12	and	and	CCONJ
can-1681	130	13	show	show	VERB
can-1681	130	14	good	good	ADJ
can-1681	130	15	compatibility	compatibility	NOUN
can-1681	130	16	with	with	ADP
can-1681	130	17	eye	eye	NOUN
can-1681	130	18	tissues[50,51	tissues[50,51	PROPN
can-1681	130	19	]	]	PUNCT
can-1681	130	20	.	.	PUNCT
can-1681	131	1	examples	example	NOUN
can-1681	131	2	of	of	ADP
can-1681	131	3	applications	application	NOUN
can-1681	131	4	of	of	ADP
can-1681	131	5	such	such	ADJ
can-1681	131	6	nanoparticles	nanoparticle	NOUN
can-1681	131	7	include	include	VERB
can-1681	131	8	intravitreal	intravitreal	ADJ
can-1681	131	9	nanoliposome	nanoliposome	NOUN
can-1681	131	10	suspensions	suspension	NOUN
can-1681	131	11	of	of	ADP
can-1681	131	12	prednisolone	prednisolone	PROPN
can-1681	131	13	and	and	CCONJ
can-1681	131	14	infliximab[52,53	infliximab[52,53	PROPN
can-1681	131	15	]	]	PUNCT
can-1681	131	16	.	.	PUNCT
can-1681	132	1	3.2	3.2	NUM
can-1681	132	2	polymer	polymer	NOUN
can-1681	132	3	nanoparticles	nanoparticle	NOUN
can-1681	132	4	polymer	polymer	NOUN
can-1681	132	5	micelles	micelle	NOUN
can-1681	132	6	are	be	AUX
can-1681	132	7	self	self	NOUN
can-1681	132	8	-	-	PUNCT
can-1681	132	9	assembled	assemble	VERB
can-1681	132	10	nanoscopic	nanoscopic	ADJ
can-1681	132	11	core	core	NOUN
can-1681	132	12	-	-	PUNCT
can-1681	132	13	shell	shell	NOUN
can-1681	132	14	structures	structure	NOUN
can-1681	132	15	formed	form	VERB
can-1681	132	16	by	by	ADP
can-1681	132	17	amphiphilic	amphiphilic	ADJ
can-1681	132	18	copolymer	copolymer	NOUN
can-1681	132	19	inside	inside	ADP
can-1681	132	20	water	water	NOUN
can-1681	132	21	.	.	PUNCT
can-1681	133	1	the	the	DET
can-1681	133	2	core	core	NOUN
can-1681	133	3	/	/	SYM
can-1681	133	4	shell	shell	NOUN
can-1681	133	5	structure	structure	NOUN
can-1681	133	6	allows	allow	VERB
can-1681	133	7	the	the	DET
can-1681	133	8	hydrophobic	hydrophobic	NOUN
can-1681	133	9	drug	drug	NOUN
can-1681	133	10	to	to	PART
can-1681	133	11	be	be	AUX
can-1681	133	12	encapsulated	encapsulate	VERB
can-1681	133	13	in	in	ADP
can-1681	133	14	its	its	PRON
can-1681	133	15	hydrophobic	hydrophobic	NOUN
can-1681	133	16	core	core	NOUN
can-1681	133	17	.	.	PUNCT
can-1681	134	1	because	because	SCONJ
can-1681	134	2	the	the	DET
can-1681	134	3	core	core	NOUN
can-1681	134	4	is	be	AUX
can-1681	134	5	protected	protect	VERB
can-1681	134	6	by	by	ADP
can-1681	134	7	the	the	DET
can-1681	134	8	hydrophilic	hydrophilic	ADJ
can-1681	134	9	crown	crown	NOUN
can-1681	134	10	,	,	PUNCT
can-1681	134	11	the	the	DET
can-1681	134	12	bioavailability	bioavailability	NOUN
can-1681	134	13	of	of	ADP
can-1681	134	14	the	the	DET
can-1681	134	15	drug	drug	NOUN
can-1681	134	16	in	in	ADP
can-1681	134	17	the	the	DET
can-1681	134	18	local	local	ADJ
can-1681	134	19	administration	administration	NOUN
can-1681	134	20	of	of	ADP
can-1681	134	21	ocular	ocular	ADJ
can-1681	134	22	tissue	tissue	NOUN
can-1681	134	23	is	be	AUX
can-1681	134	24	significantly	significantly	ADV
can-1681	134	25	prolonged[54,55	prolonged[54,55	NOUN
can-1681	134	26	]	]	PUNCT
can-1681	134	27	.	.	PUNCT
can-1681	135	1	an	an	DET
can-1681	135	2	experimental	experimental	ADJ
can-1681	135	3	study	study	NOUN
can-1681	135	4	conducted	conduct	VERB
can-1681	135	5	by	by	ADP
can-1681	135	6	mittal	mittal	PROPN
can-1681	135	7	et	et	PROPN
can-1681	135	8	al	al	PROPN
can-1681	135	9	.	.	PROPN
can-1681	136	1	in	in	ADP
can-1681	136	2	rabbits	rabbit	NOUN
can-1681	136	3	showed	show	VERB
can-1681	136	4	that	that	SCONJ
can-1681	136	5	timolol	timolol	NOUN
can-1681	136	6	maleate	maleate	NOUN
can-1681	136	7	was	be	AUX
can-1681	136	8	biocompatible	biocompatible	ADJ
can-1681	136	9	with	with	ADP
can-1681	136	10	the	the	DET
can-1681	136	11	71	71	NUM
can-1681	136	12	cornea	cornea	NOUN
can-1681	136	13	,	,	PUNCT
can-1681	136	14	and	and	CCONJ
can-1681	136	15	the	the	DET
can-1681	136	16	intraocular	intraocular	ADJ
can-1681	136	17	pressure	pressure	NOUN
can-1681	136	18	(	(	PUNCT
can-1681	136	19	iop	iop	NOUN
can-1681	136	20	)	)	PUNCT
can-1681	136	21	decreased	decrease	VERB
can-1681	136	22	for	for	ADP
can-1681	136	23	a	a	DET
can-1681	136	24	longer	long	ADJ
can-1681	136	25	time.[56	time.[56	NUM
can-1681	136	26	]	]	X
can-1681	136	27	.	.	PUNCT
can-1681	137	1	3.3	3.3	NUM
can-1681	137	2	nano	nano	NOUN
can-1681	137	3	suspension	suspension	NOUN
can-1681	137	4	nano	nano	NOUN
can-1681	137	5	suspensions	suspension	NOUN
can-1681	137	6	are	be	AUX
can-1681	137	7	colloidal	colloidal	NOUN
can-1681	137	8	dispersions	dispersion	NOUN
can-1681	137	9	in	in	ADP
can-1681	137	10	which	which	PRON
can-1681	137	11	the	the	DET
can-1681	137	12	hydrophobic	hydrophobic	NOUN
can-1681	137	13	phase	phase	NOUN
can-1681	137	14	is	be	AUX
can-1681	137	15	uniformly	uniformly	ADV
can-1681	137	16	dispersed	disperse	VERB
can-1681	137	17	in	in	ADP
can-1681	137	18	the	the	DET
can-1681	137	19	aqueous	aqueous	ADJ
can-1681	137	20	medium	medium	NOUN
can-1681	137	21	with	with	ADP
can-1681	137	22	the	the	DET
can-1681	137	23	help	help	NOUN
can-1681	137	24	of	of	ADP
can-1681	137	25	surfactant[9	surfactant[9	NOUN
can-1681	137	26	]	]	PUNCT
can-1681	137	27	.	.	PUNCT
can-1681	138	1	for	for	ADP
can-1681	138	2	example	example	NOUN
can-1681	138	3	,	,	PUNCT
can-1681	138	4	prednisone	prednisone	NOUN
can-1681	138	5	,	,	PUNCT
can-1681	138	6	dexamethasone	dexamethasone	NOUN
can-1681	138	7	,	,	PUNCT
can-1681	138	8	hydrocortisone	hydrocortisone	PROPN
can-1681	138	9	,	,	PUNCT
can-1681	138	10	and	and	CCONJ
can-1681	138	11	other	other	ADJ
can-1681	138	12	corticosteroids	corticosteroid	NOUN
can-1681	138	13	have	have	AUX
can-1681	138	14	been	be	AUX
can-1681	138	15	administered	administer	VERB
can-1681	138	16	through	through	ADP
can-1681	138	17	nanosuspensions	nanosuspension	NOUN
can-1681	138	18	to	to	PART
can-1681	138	19	treat	treat	VERB
can-1681	138	20	anterior	anterior	ADJ
can-1681	138	21	inflammation	inflammation	NOUN
can-1681	138	22	without	without	ADP
can-1681	138	23	the	the	DET
can-1681	138	24	expected	expect	VERB
can-1681	138	25	side	side	NOUN
can-1681	138	26	effects	effect	NOUN
can-1681	138	27	of	of	ADP
can-1681	138	28	high	high	ADJ
can-1681	138	29	-	-	PUNCT
can-1681	138	30	dose	dose	NOUN
can-1681	138	31	application	application	NOUN
can-1681	138	32	,	,	PUNCT
can-1681	138	33	such	such	ADJ
can-1681	138	34	as	as	ADP
can-1681	138	35	cataract	cataract	NOUN
can-1681	138	36	and	and	CCONJ
can-1681	138	37	glaucomatous	glaucomatous	ADJ
can-1681	138	38	optic	optic	NOUN
can-1681	138	39	neuropathy	neuropathy	ADJ
can-1681	138	40	.	.	PUNCT
can-1681	139	1	3.4	3.4	NUM
can-1681	139	2	dendrimer	dendrimer	NOUN
can-1681	139	3	dendrimers	dendrimer	NOUN
can-1681	139	4	are	be	AUX
can-1681	139	5	monodisperse	monodisperse	ADJ
can-1681	139	6	macro	macro	NOUN
can-1681	139	7	-	-	NOUN
can-1681	139	8	molecules	molecule	NOUN
can-1681	139	9	.	.	PUNCT
can-1681	140	1	several	several	ADJ
can-1681	140	2	reaction	reaction	NOUN
can-1681	140	3	end	end	NOUN
can-1681	140	4	groups	group	NOUN
can-1681	140	5	form	form	VERB
can-1681	140	6	an	an	DET
can-1681	140	7	inner	inner	ADJ
can-1681	140	8	cavity	cavity	NOUN
can-1681	140	9	around	around	ADP
can-1681	140	10	a	a	DET
can-1681	140	11	small	small	ADJ
can-1681	140	12	molecule	molecule	NOUN
can-1681	140	13	.	.	PUNCT
can-1681	141	1	its	its	PRON
can-1681	141	2	tree	tree	NOUN
can-1681	141	3	branch	branch	NOUN
can-1681	141	4	structure	structure	NOUN
can-1681	141	5	presents	present	VERB
can-1681	141	6	various	various	ADJ
can-1681	141	7	repeated	repeat	VERB
can-1681	141	8	terminal	terminal	ADJ
can-1681	141	9	groups	group	NOUN
can-1681	141	10	.	.	PUNCT
can-1681	142	1	in	in	ADP
can-1681	142	2	particular	particular	ADJ
can-1681	142	3	,	,	PUNCT
can-1681	142	4	low	low	ADJ
can-1681	142	5	-	-	PUNCT
can-1681	142	6	generation	generation	NOUN
can-1681	142	7	dendrimers	dendrimer	NOUN
can-1681	142	8	can	can	AUX
can-1681	142	9	encapsulate	encapsulate	VERB
can-1681	142	10	hydrophobic	hydrophobic	NOUN
can-1681	142	11	drug	drug	NOUN
can-1681	142	12	molecules	molecule	NOUN
can-1681	142	13	in	in	ADP
can-1681	142	14	their	their	PRON
can-1681	142	15	inner	inner	ADJ
can-1681	142	16	cavities	cavity	NOUN
can-1681	142	17	.	.	PUNCT
can-1681	143	1	due	due	ADP
can-1681	143	2	to	to	ADP
can-1681	143	3	this	this	DET
can-1681	143	4	unique	unique	ADJ
can-1681	143	5	structure	structure	NOUN
can-1681	143	6	,	,	PUNCT
can-1681	143	7	dendrimers	dendrimer	NOUN
can-1681	143	8	allow	allow	VERB
can-1681	143	9	the	the	DET
can-1681	143	10	dissolution	dissolution	NOUN
can-1681	143	11	of	of	ADP
can-1681	143	12	drugs	drug	NOUN
can-1681	143	13	with	with	ADP
can-1681	143	14	poor	poor	ADJ
can-1681	143	15	water	water	NOUN
can-1681	143	16	solubility	solubility	NOUN
can-1681	143	17	.	.	PUNCT
can-1681	144	1	in	in	ADP
can-1681	144	2	addition	addition	NOUN
can-1681	144	3	,	,	PUNCT
can-1681	144	4	dendrimers	dendrimer	NOUN
can-1681	144	5	can	can	AUX
can-1681	144	6	be	be	AUX
can-1681	144	7	considered	consider	VERB
can-1681	144	8	real	real	ADJ
can-1681	144	9	simulations	simulation	NOUN
can-1681	144	10	of	of	ADP
can-1681	144	11	globular	globular	ADJ
can-1681	144	12	proteins	protein	NOUN
can-1681	144	13	.	.	PUNCT
can-1681	145	1	they	they	PRON
can-1681	145	2	are	be	AUX
can-1681	145	3	called	call	VERB
can-1681	145	4	“	"	PUNCT
can-1681	145	5	artificial	artificial	ADJ
can-1681	145	6	proteins	protein	NOUN
can-1681	145	7	”	"	PUNCT
can-1681	145	8	because	because	SCONJ
can-1681	145	9	of	of	ADP
can-1681	145	10	their	their	PRON
can-1681	145	11	systematicness	systematicness	NOUN
can-1681	145	12	,	,	PUNCT
can-1681	145	13	electrophoresis	electrophoresis	NOUN
can-1681	145	14	,	,	PUNCT
can-1681	145	15	size	size	NOUN
can-1681	145	16	scale	scale	NOUN
can-1681	145	17	,	,	PUNCT
can-1681	145	18	and	and	CCONJ
can-1681	145	19	other	other	ADJ
can-1681	145	20	bionic	bionic	ADJ
can-1681	145	21	properties[57,58	properties[57,58	NOUN
can-1681	145	22	]	]	PUNCT
can-1681	145	23	.	.	PUNCT
can-1681	146	1	drugs	drug	NOUN
can-1681	146	2	developed	develop	VERB
can-1681	146	3	using	use	VERB
can-1681	146	4	this	this	DET
can-1681	146	5	technology	technology	NOUN
can-1681	146	6	include	include	VERB
can-1681	146	7	intravitreal	intravitreal	ADJ
can-1681	146	8	injection	injection	NOUN
can-1681	146	9	of	of	ADP
can-1681	146	10	fluocinolone	fluocinolone	NOUN
can-1681	146	11	acetoacetate	acetoacetate	NOUN
can-1681	146	12	for	for	ADP
can-1681	146	13	retinitis	retinitis	ADJ
can-1681	146	14	pigmentosa	pigmentosa	NOUN
can-1681	146	15	and	and	CCONJ
can-1681	146	16	subconjunctival	subconjunctival	ADJ
can-1681	146	17	carboplatin	carboplatin	NOUN
can-1681	146	18	for	for	ADP
can-1681	146	19	retinoblastoma[59,60	retinoblastoma[59,60	NOUN
can-1681	146	20	]	]	PUNCT
can-1681	146	21	.	.	PUNCT
can-1681	147	1	3.5	3.5	NUM
can-1681	147	2	nano	nano	NOUN
can-1681	147	3	micelles	micelle	NOUN
can-1681	147	4	nano	nano	NOUN
can-1681	147	5	micelles	micelle	NOUN
can-1681	147	6	are	be	AUX
can-1681	147	7	drug	drug	NOUN
can-1681	147	8	delivery	delivery	NOUN
can-1681	147	9	systems	system	NOUN
can-1681	147	10	composed	compose	VERB
can-1681	147	11	of	of	ADP
can-1681	147	12	hydrophobic	hydrophobic	NOUN
can-1681	147	13	nuclei	nucleus	NOUN
can-1681	147	14	and	and	CCONJ
can-1681	147	15	hydrophilic	hydrophilic	ADJ
can-1681	147	16	caps	cap	NOUN
can-1681	147	17	,	,	PUNCT
can-1681	147	18	which	which	PRON
can-1681	147	19	allow	allow	VERB
can-1681	147	20	the	the	DET
can-1681	147	21	dissolution	dissolution	NOUN
can-1681	147	22	of	of	ADP
can-1681	147	23	hydrophobic	hydrophobic	NOUN
can-1681	147	24	drugs	drug	NOUN
can-1681	147	25	and	and	CCONJ
can-1681	147	26	produce	produce	VERB
can-1681	147	27	transparent	transparent	ADJ
can-1681	147	28	aqueous	aqueous	ADJ
can-1681	147	29	preparations	preparation	NOUN
can-1681	147	30	when	when	SCONJ
can-1681	147	31	they	they	PRON
can-1681	147	32	are	be	AUX
can-1681	147	33	ready	ready	ADJ
can-1681	147	34	to	to	PART
can-1681	147	35	be	be	AUX
can-1681	147	36	administered	administer	VERB
can-1681	147	37	to	to	ADP
can-1681	147	38	the	the	DET
can-1681	147	39	anterior	anterior	ADJ
can-1681	147	40	segment	segment	NOUN
can-1681	147	41	of	of	ADP
can-1681	147	42	the	the	DET
can-1681	147	43	eyeball	eyeball	NOUN
can-1681	147	44	.	.	PUNCT
can-1681	148	1	one	one	NUM
can-1681	148	2	of	of	ADP
can-1681	148	3	the	the	DET
can-1681	148	4	drugs	drug	NOUN
can-1681	148	5	used	use	VERB
can-1681	148	6	in	in	ADP
can-1681	148	7	this	this	DET
can-1681	148	8	nanotechnology	nanotechnology	NOUN
can-1681	148	9	is	be	AUX
can-1681	148	10	cyclosporine	cyclosporine	ADJ
can-1681	148	11	.	.	PUNCT
can-1681	149	1	a	a	DET
can-1681	149	2	phase	phase	NOUN
can-1681	149	3	iii	iii	NUM
can-1681	149	4	clinical	clinical	ADJ
can-1681	149	5	trial	trial	NOUN
can-1681	149	6	has	have	AUX
can-1681	149	7	proved	prove	VERB
can-1681	149	8	that	that	SCONJ
can-1681	149	9	it	it	PRON
can-1681	149	10	is	be	AUX
can-1681	149	11	effective	effective	ADJ
can-1681	149	12	,	,	PUNCT
can-1681	149	13	safe	safe	ADJ
can-1681	149	14	,	,	PUNCT
can-1681	149	15	and	and	CCONJ
can-1681	149	16	rapid	rapid	ADJ
can-1681	149	17	in	in	ADP
can-1681	149	18	the	the	DET
can-1681	149	19	treatment	treatment	NOUN
can-1681	149	20	of	of	ADP
can-1681	149	21	keratoconjunctivitis	keratoconjunctivitis	PROPN
can-1681	149	22	sicca[61	sicca[61	PROPN
can-1681	149	23	]	]	PUNCT
can-1681	149	24	.	.	PUNCT
can-1681	150	1	3.6	3.6	NUM
can-1681	150	2	niosome	niosome	NOUN
can-1681	150	3	niosomes	niosome	NOUN
can-1681	150	4	are	be	AUX
can-1681	150	5	two	two	NUM
can-1681	150	6	-	-	PUNCT
can-1681	150	7	layer	layer	NOUN
can-1681	150	8	non	non	ADJ
can-1681	150	9	-	-	ADJ
can-1681	150	10	ionic	ionic	ADJ
can-1681	150	11	surfactant	surfactant	ADJ
can-1681	150	12	vesicles	vesicle	NOUN
can-1681	150	13	that	that	PRON
can-1681	150	14	can	can	AUX
can-1681	150	15	capture	capture	VERB
can-1681	150	16	hydrophilic	hydrophilic	ADJ
can-1681	150	17	and	and	CCONJ
can-1681	150	18	lipophilic	lipophilic	ADJ
can-1681	150	19	drugs	drug	NOUN
can-1681	150	20	.	.	PUNCT
can-1681	151	1	niosomes	niosome	NOUN
can-1681	151	2	are	be	AUX
can-1681	151	3	chemically	chemically	ADV
can-1681	151	4	stable	stable	ADJ
can-1681	151	5	,	,	PUNCT
can-1681	151	6	and	and	CCONJ
can-1681	151	7	their	their	PRON
can-1681	151	8	non	non	ADJ
can-1681	151	9	-	-	ADJ
can-1681	151	10	ionic	ionic	ADJ
can-1681	151	11	properties	property	NOUN
can-1681	151	12	make	make	VERB
can-1681	151	13	them	they	PRON
can-1681	151	14	less	less	ADV
can-1681	151	15	toxic	toxic	ADJ
can-1681	151	16	.	.	PUNCT
can-1681	152	1	due	due	ADP
can-1681	152	2	to	to	ADP
can-1681	152	3	its	its	PRON
can-1681	152	4	hydrophilic	hydrophilic	ADJ
can-1681	152	5	surface	surface	NOUN
can-1681	152	6	,	,	PUNCT
can-1681	152	7	niosomes	niosome	NOUN
can-1681	152	8	can	can	AUX
can-1681	152	9	easily	easily	ADV
can-1681	152	10	interact	interact	VERB
can-1681	152	11	and	and	CCONJ
can-1681	152	12	cross	cross	VERB
can-1681	152	13	the	the	DET
can-1681	152	14	tear	tear	ADJ
can-1681	152	15	film	film	NOUN
can-1681	152	16	barrier	barrier	NOUN
can-1681	152	17	,	,	PUNCT
can-1681	152	18	so	so	SCONJ
can-1681	152	19	they	they	PRON
can-1681	152	20	can	can	AUX
can-1681	152	21	reach	reach	VERB
can-1681	152	22	the	the	DET
can-1681	152	23	cornea	cornea	NOUN
can-1681	152	24	/	/	SYM
can-1681	152	25	conjunctival	conjunctival	NOUN
can-1681	152	26	tissue[63	tissue[63	NOUN
can-1681	152	27	]	]	PUNCT
can-1681	152	28	.	.	PUNCT
can-1681	153	1	niosomes	niosome	NOUN
can-1681	153	2	have	have	AUX
can-1681	153	3	been	be	AUX
can-1681	153	4	evaluated	evaluate	VERB
can-1681	153	5	as	as	ADP
can-1681	153	6	anticholinergic	anticholinergic	ADJ
can-1681	153	7	and	and	CCONJ
can-1681	153	8	antibiological	antibiological	ADJ
can-1681	153	9	agents[62,64,65	agents[62,64,65	NOUN
can-1681	153	10	]	]	PUNCT
can-1681	153	11	.	.	PUNCT
can-1681	154	1	the	the	DET
can-1681	154	2	most	most	ADV
can-1681	154	3	important	important	ADJ
can-1681	154	4	characteristics	characteristic	NOUN
can-1681	154	5	of	of	ADP
can-1681	154	6	the	the	DET
can-1681	154	7	drug	drug	NOUN
can-1681	154	8	delivery	delivery	NOUN
can-1681	154	9	carrier	carrier	NOUN
can-1681	154	10	for	for	ADP
can-1681	154	11	the	the	DET
can-1681	154	12	eye	eye	NOUN
can-1681	154	13	are	be	AUX
can-1681	154	14	:	:	PUNCT
can-1681	154	15	(	(	PUNCT
can-1681	154	16	i	i	NOUN
can-1681	154	17	)	)	PUNCT
can-1681	154	18	the	the	DET
can-1681	154	19	size	size	NOUN
can-1681	154	20	of	of	ADP
can-1681	154	21	the	the	DET
can-1681	154	22	gallbladder	gallbladder	NOUN
can-1681	154	23	is	be	AUX
can-1681	154	24	large	large	ADJ
can-1681	154	25	enough	enough	ADV
can-1681	154	26	to	to	PART
can-1681	154	27	resist	resist	VERB
can-1681	154	28	the	the	DET
can-1681	154	29	drainage	drainage	NOUN
can-1681	154	30	caused	cause	VERB
can-1681	154	31	by	by	ADP
can-1681	154	32	reflex	reflex	ADJ
can-1681	154	33	tear	tear	NOUN
can-1681	154	34	and	and	CCONJ
can-1681	154	35	blinking	blink	VERB
can-1681	154	36	;	;	PUNCT
can-1681	154	37	(	(	PUNCT
can-1681	154	38	ii	ii	NOUN
can-1681	154	39	)	)	PUNCT
can-1681	154	40	the	the	DET
can-1681	154	41	presence	presence	NOUN
can-1681	154	42	of	of	ADP
can-1681	154	43	an	an	DET
can-1681	154	44	irregular	irregular	ADJ
can-1681	154	45	shape	shape	NOUN
can-1681	154	46	so	so	SCONJ
can-1681	154	47	that	that	SCONJ
can-1681	154	48	it	it	PRON
can-1681	154	49	can	can	AUX
can-1681	154	50	be	be	AUX
can-1681	154	51	correctly	correctly	ADV
can-1681	154	52	installed	instal	VERB
can-1681	154	53	at	at	ADP
can-1681	154	54	the	the	DET
can-1681	154	55	bottom	bottom	NOUN
can-1681	154	56	of	of	ADP
can-1681	154	57	the	the	DET
can-1681	154	58	eye	eye	NOUN
can-1681	154	59	bag	bag	NOUN
can-1681	154	60	and	and	CCONJ
can-1681	154	61	accommodated	accommodate	VERB
can-1681	154	62	on	on	ADP
can-1681	154	63	the	the	DET
can-1681	154	64	surface	surface	NOUN
can-1681	154	65	of	of	ADP
can-1681	154	66	the	the	DET
can-1681	154	67	eye	eye	NOUN
can-1681	154	68	;	;	PUNCT
can-1681	154	69	(	(	PUNCT
can-1681	154	70	iii	iii	X
can-1681	154	71	)	)	PUNCT
can-1681	154	72	it	it	PRON
can-1681	154	73	is	be	AUX
can-1681	154	74	preferable	preferable	ADJ
can-1681	154	75	to	to	PART
can-1681	154	76	be	be	AUX
can-1681	154	77	heat	heat	NOUN
can-1681	154	78	sensitive	sensitive	ADJ
can-1681	154	79	and	and	CCONJ
can-1681	154	80	release	release	VERB
can-1681	154	81	the	the	DET
can-1681	154	82	drug	drug	NOUN
can-1681	154	83	content	content	NOUN
can-1681	154	84	in	in	ADP
can-1681	154	85	a	a	DET
can-1681	154	86	controlled	control	VERB
can-1681	154	87	manner	manner	NOUN
can-1681	154	88	,	,	PUNCT
can-1681	154	89	but	but	CCONJ
can-1681	154	90	at	at	ADP
can-1681	154	91	the	the	DET
can-1681	154	92	same	same	ADJ
can-1681	154	93	time	time	NOUN
can-1681	154	94	,	,	PUNCT
can-1681	154	95	before	before	ADP
can-1681	154	96	removal	removal	NOUN
can-1681	154	97	with	with	ADP
can-1681	154	98	blinking	blink	VERB
can-1681	154	99	and	and	CCONJ
can-1681	154	100	nasolacrimal	nasolacrimal	ADJ
can-1681	154	101	duct	duct	NOUN
can-1681	154	102	drainage[66,67	drainage[66,67	NOUN
can-1681	154	103	]	]	PUNCT
can-1681	154	104	.	.	PUNCT
can-1681	155	1	3.7	3.7	NUM
can-1681	155	2	cube	cube	VERB
can-1681	155	3	the	the	DET
can-1681	155	4	structure	structure	NOUN
can-1681	155	5	of	of	ADP
can-1681	155	6	the	the	DET
can-1681	155	7	cube	cube	NOUN
can-1681	155	8	consists	consist	VERB
can-1681	155	9	of	of	ADP
can-1681	155	10	a	a	DET
can-1681	155	11	continuous	continuous	ADJ
can-1681	155	12	,	,	PUNCT
can-1681	155	13	highly	highly	ADV
can-1681	155	14	distorted	distorted	ADJ
can-1681	155	15	lipid	lipid	NOUN
can-1681	155	16	double	double	ADJ
can-1681	155	17	chain	chain	NOUN
can-1681	155	18	with	with	ADP
can-1681	155	19	two	two	NUM
can-1681	155	20	disjoint	disjoint	NOUN
can-1681	155	21	and	and	CCONJ
can-1681	155	22	consistent	consistent	ADJ
can-1681	155	23	waterways	waterway	NOUN
can-1681	155	24	.	.	PUNCT
can-1681	156	1	compared	compare	VERB
can-1681	156	2	with	with	ADP
can-1681	156	3	the	the	DET
can-1681	156	4	simple	simple	ADJ
can-1681	156	5	liposome	liposome	NOUN
can-1681	156	6	structure	structure	NOUN
can-1681	156	7	,	,	PUNCT
can-1681	156	8	the	the	DET
can-1681	156	9	cube	cube	NOUN
can-1681	156	10	has	have	AUX
can-1681	156	11	increased	increase	VERB
can-1681	156	12	surface	surface	NOUN
can-1681	156	13	area	area	NOUN
can-1681	156	14	and	and	CCONJ
can-1681	156	15	the	the	DET
can-1681	156	16	ability	ability	NOUN
can-1681	156	17	to	to	PART
can-1681	156	18	encapsulate	encapsulate	VERB
can-1681	156	19	various	various	ADJ
can-1681	156	20	hydrophilic	hydrophilic	NOUN
can-1681	156	21	,	,	PUNCT
can-1681	156	22	hydrophobic	hydrophobic	NOUN
can-1681	156	23	,	,	PUNCT
can-1681	156	24	and	and	CCONJ
can-1681	156	25	amphiphilic	amphiphilic	ADJ
can-1681	156	26	molecules	molecule	NOUN
can-1681	156	27	.	.	PUNCT
can-1681	157	1	due	due	ADP
can-1681	157	2	to	to	ADP
can-1681	157	3	the	the	DET
can-1681	157	4	strong	strong	ADJ
can-1681	157	5	electric	electric	ADJ
can-1681	157	6	repulsion	repulsion	NOUN
can-1681	157	7	and	and	CCONJ
can-1681	157	8	the	the	DET
can-1681	157	9	high	high	ADJ
can-1681	157	10	proportion	proportion	NOUN
can-1681	157	11	of	of	ADP
can-1681	157	12	liposomes[68–70	liposomes[68–70	PROPN
can-1681	157	13	]	]	PUNCT
can-1681	157	14	,	,	PUNCT
can-1681	157	15	cuboids	cuboid	NOUN
can-1681	157	16	have	have	VERB
can-1681	157	17	higher	high	ADJ
can-1681	157	18	physicochemical	physicochemical	ADJ
can-1681	157	19	stability	stability	NOUN
can-1681	157	20	than	than	ADP
can-1681	157	21	liposomes	liposome	NOUN
can-1681	157	22	.	.	PUNCT
can-1681	158	1	the	the	DET
can-1681	158	2	use	use	NOUN
can-1681	158	3	of	of	ADP
can-1681	158	4	dexamethasone	dexamethasone	NOUN
can-1681	158	5	in	in	ADP
can-1681	158	6	eye	eye	NOUN
can-1681	158	7	drops	drop	NOUN
can-1681	158	8	is	be	AUX
can-1681	158	9	associated	associate	VERB
can-1681	158	10	with	with	ADP
can-1681	158	11	this	this	DET
can-1681	158	12	nanoparticle	nanoparticle	NOUN
can-1681	158	13	,	,	PUNCT
can-1681	158	14	indicating	indicate	VERB
can-1681	158	15	a	a	DET
can-1681	158	16	higher	high	ADJ
can-1681	158	17	availability	availability	NOUN
can-1681	158	18	of	of	ADP
can-1681	158	19	the	the	DET
can-1681	158	20	drug	drug	NOUN
can-1681	158	21	in	in	ADP
can-1681	158	22	aqueous	aqueous	ADJ
can-1681	158	23	humor[71	humor[71	NOUN
can-1681	158	24	]	]	PUNCT
can-1681	158	25	.	.	PUNCT
can-1681	159	1	3.8	3.8	NUM
can-1681	159	2	hydrogel	hydrogel	NOUN
can-1681	159	3	hydrogels	hydrogel	NOUN
can-1681	159	4	are	be	AUX
can-1681	159	5	a	a	DET
can-1681	159	6	network	network	NOUN
can-1681	159	7	composed	compose	VERB
can-1681	159	8	of	of	ADP
can-1681	159	9	multifunctional	multifunctional	ADJ
can-1681	159	10	monomers	monomer	NOUN
can-1681	159	11	and	and	CCONJ
can-1681	159	12	relays	relay	NOUN
can-1681	159	13	,	,	PUNCT
can-1681	159	14	which	which	PRON
can-1681	159	15	react	react	VERB
can-1681	159	16	to	to	PART
can-1681	159	17	form	form	VERB
can-1681	159	18	a	a	DET
can-1681	159	19	flexible	flexible	ADJ
can-1681	159	20	underwater	underwater	ADJ
can-1681	159	21	structure	structure	NOUN
can-1681	159	22	.	.	PUNCT
can-1681	160	1	because	because	SCONJ
can-1681	160	2	the	the	DET
can-1681	160	3	porosity	porosity	NOUN
can-1681	160	4	of	of	ADP
can-1681	160	5	the	the	DET
can-1681	160	6	hydrogel	hydrogel	NOUN
can-1681	160	7	matrix	matrix	NOUN
can-1681	160	8	can	can	AUX
can-1681	160	9	be	be	AUX
can-1681	160	10	adjusted	adjust	VERB
can-1681	160	11	by	by	ADP
can-1681	160	12	changing	change	VERB
can-1681	160	13	the	the	DET
can-1681	160	14	crosslinking	crosslinke	VERB
can-1681	160	15	density	density	NOUN
can-1681	160	16	,	,	PUNCT
can-1681	160	17	the	the	DET
can-1681	160	18	hydrogel	hydrogel	NOUN
can-1681	160	19	network	network	NOUN
can-1681	160	20	has	have	AUX
can-1681	160	21	been	be	AUX
can-1681	160	22	widely	widely	ADV
can-1681	160	23	studied	study	VERB
can-1681	160	24	as	as	ADP
can-1681	160	25	a	a	DET
can-1681	160	26	controlled	control	VERB
can-1681	160	27	and	and	CCONJ
can-1681	160	28	continuous	continuous	ADJ
can-1681	160	29	drug	drug	NOUN
can-1681	160	30	delivery	delivery	NOUN
can-1681	160	31	system	system	NOUN
can-1681	160	32	.	.	PUNCT
can-1681	161	1	the	the	DET
can-1681	161	2	ability	ability	NOUN
can-1681	161	3	to	to	PART
can-1681	161	4	change	change	VERB
can-1681	161	5	with	with	ADP
can-1681	161	6	the	the	DET
can-1681	161	7	surrounding	surround	VERB
can-1681	161	8	environment	environment	NOUN
can-1681	161	9	is	be	AUX
can-1681	161	10	of	of	ADP
can-1681	161	11	great	great	ADJ
can-1681	161	12	significance	significance	NOUN
can-1681	161	13	for	for	ADP
can-1681	161	14	the	the	DET
can-1681	161	15	formation	formation	NOUN
can-1681	161	16	of	of	ADP
can-1681	161	17	hydrogels	hydrogel	NOUN
can-1681	161	18	in	in	ADP
can-1681	161	19	situ	situ	NOUN
can-1681	161	20	.	.	PUNCT
can-1681	162	1	hydrogels	hydrogel	NOUN
can-1681	162	2	will	will	AUX
can-1681	162	3	be	be	AUX
can-1681	162	4	crosslinked	crosslinke	VERB
can-1681	162	5	when	when	SCONJ
can-1681	162	6	the	the	DET
can-1681	162	7	temperature	temperature	NOUN
can-1681	162	8	rises	rise	VERB
can-1681	162	9	from	from	ADP
can-1681	162	10	room	room	NOUN
can-1681	162	11	temperature	temperature	NOUN
can-1681	162	12	to	to	ADP
can-1681	162	13	body	body	NOUN
can-1681	162	14	temperature	temperature	NOUN
can-1681	162	15	,	,	PUNCT
can-1681	162	16	and	and	CCONJ
can-1681	162	17	their	their	PRON
can-1681	162	18	phase	phase	NOUN
can-1681	162	19	-	-	PUNCT
can-1681	162	20	controlled	control	VERB
can-1681	162	21	release	release	NOUN
can-1681	162	22	is	be	AUX
can-1681	162	23	affected	affect	VERB
can-1681	162	24	by	by	ADP
can-1681	162	25	ph	ph	ADJ
can-1681	162	26	value	value	NOUN
can-1681	162	27	or	or	CCONJ
can-1681	162	28	light	light	ADJ
can-1681	162	29	stimulation[72,73	stimulation[72,73	NOUN
can-1681	162	30	]	]	PUNCT
can-1681	162	31	.	.	PUNCT
can-1681	163	1	72	72	NUM
can-1681	163	2	controlled	control	VERB
can-1681	163	3	release	release	NOUN
can-1681	163	4	silicone	silicone	NOUN
can-1681	163	5	and	and	CCONJ
can-1681	163	6	hydrogel	hydrogel	NOUN
can-1681	163	7	contact	contact	NOUN
can-1681	163	8	lenses	lense	NOUN
can-1681	163	9	containing	contain	VERB
can-1681	163	10	timolol	timolol	NOUN
can-1681	163	11	are	be	AUX
can-1681	163	12	a	a	DET
can-1681	163	13	new	new	ADJ
can-1681	163	14	technology	technology	NOUN
can-1681	163	15	developed	develop	VERB
can-1681	163	16	in	in	ADP
can-1681	163	17	recent	recent	ADJ
can-1681	163	18	years[74]and	years[74]and	PROPN
can-1681	163	19	have	have	VERB
can-1681	163	20	good	good	ADJ
can-1681	163	21	application	application	NOUN
can-1681	163	22	prospects	prospect	NOUN
can-1681	163	23	.	.	PUNCT
can-1681	164	1	3.9	3.9	NUM
can-1681	164	2	polymer	polymer	NOUN
can-1681	164	3	nanofibers	nanofiber	NOUN
can-1681	164	4	nanofibers	nanofiber	NOUN
can-1681	164	5	are	be	AUX
can-1681	164	6	made	make	VERB
can-1681	164	7	of	of	ADP
can-1681	164	8	solid	solid	ADJ
can-1681	164	9	fiber	fiber	NOUN
can-1681	164	10	materials	material	NOUN
can-1681	164	11	with	with	ADP
can-1681	164	12	a	a	DET
can-1681	164	13	diameter	diameter	NOUN
can-1681	164	14	of	of	ADP
can-1681	164	15	less	less	ADJ
can-1681	164	16	than	than	ADP
can-1681	164	17	microns	micron	NOUN
can-1681	164	18	.	.	PUNCT
can-1681	165	1	they	they	PRON
can-1681	165	2	have	have	VERB
can-1681	165	3	a	a	DET
can-1681	165	4	porous	porous	ADJ
can-1681	165	5	structure	structure	NOUN
can-1681	165	6	and	and	CCONJ
can-1681	165	7	a	a	DET
can-1681	165	8	very	very	ADV
can-1681	165	9	high	high	ADJ
can-1681	165	10	surface	surface	NOUN
can-1681	165	11	area	area	NOUN
can-1681	165	12	.	.	PUNCT
can-1681	166	1	nanofibers	nanofiber	NOUN
can-1681	166	2	are	be	AUX
can-1681	166	3	nonwoven	nonwoven	ADJ
can-1681	166	4	fiber	fiber	NOUN
can-1681	166	5	structures	structure	NOUN
can-1681	166	6	similar	similar	ADJ
can-1681	166	7	to	to	ADP
can-1681	166	8	the	the	DET
can-1681	166	9	extracellular	extracellular	ADJ
can-1681	166	10	matrix	matrix	NOUN
can-1681	166	11	.	.	PUNCT
can-1681	167	1	they	they	PRON
can-1681	167	2	are	be	AUX
can-1681	167	3	composed	compose	VERB
can-1681	167	4	of	of	ADP
can-1681	167	5	highly	highly	ADV
can-1681	167	6	organized	organize	VERB
can-1681	167	7	polymer	polymer	NOUN
can-1681	167	8	fibers	fiber	NOUN
can-1681	167	9	and	and	CCONJ
can-1681	167	10	aqueous	aqueous	ADJ
can-1681	167	11	compounds	compound	NOUN
can-1681	167	12	comprised	comprise	VERB
can-1681	167	13	of	of	ADP
can-1681	167	14	protein	protein	NOUN
can-1681	167	15	polysaccharides	polysaccharide	NOUN
can-1681	167	16	to	to	PART
can-1681	167	17	support	support	VERB
can-1681	167	18	tissue	tissue	NOUN
can-1681	167	19	formation	formation	NOUN
can-1681	167	20	.	.	PUNCT
can-1681	168	1	therefore	therefore	ADV
can-1681	168	2	,	,	PUNCT
can-1681	168	3	tissue	tissue	NOUN
can-1681	168	4	engineering	engineering	NOUN
can-1681	168	5	is	be	AUX
can-1681	168	6	one	one	NUM
can-1681	168	7	of	of	ADP
can-1681	168	8	its	its	PRON
can-1681	168	9	main	main	ADJ
can-1681	168	10	applications	application	NOUN
can-1681	168	11	.	.	PUNCT
can-1681	169	1	the	the	DET
can-1681	169	2	device	device	NOUN
can-1681	169	3	developed	develop	VERB
can-1681	169	4	and	and	CCONJ
can-1681	169	5	studied	study	VERB
can-1681	169	6	is	be	AUX
can-1681	169	7	regenerative	regenerative	ADJ
can-1681	169	8	therapy	therapy	NOUN
can-1681	169	9	.	.	PUNCT
can-1681	170	1	this	this	PRON
can-1681	170	2	is	be	AUX
can-1681	170	3	to	to	PART
can-1681	170	4	protect	protect	VERB
can-1681	170	5	the	the	DET
can-1681	170	6	biocompatibility	biocompatibility	NOUN
can-1681	170	7	,	,	PUNCT
can-1681	170	8	physiology	physiology	NOUN
can-1681	170	9	,	,	PUNCT
can-1681	170	10	and	and	CCONJ
can-1681	170	11	transparency	transparency	NOUN
can-1681	170	12	of	of	ADP
can-1681	170	13	the	the	DET
can-1681	170	14	cornea[75,76	cornea[75,76	NOUN
can-1681	170	15	[	[	X
can-1681	170	16	.	.	PUNCT
can-1681	171	1	in	in	ADP
can-1681	171	2	addition	addition	NOUN
can-1681	171	3	,	,	PUNCT
can-1681	171	4	because	because	SCONJ
can-1681	171	5	the	the	DET
can-1681	171	6	diameter	diameter	NOUN
can-1681	171	7	of	of	ADP
can-1681	171	8	nanofibers	nanofiber	NOUN
can-1681	171	9	is	be	AUX
can-1681	171	10	very	very	ADV
can-1681	171	11	small	small	ADJ
can-1681	171	12	and	and	CCONJ
can-1681	171	13	the	the	DET
can-1681	171	14	surface	surface	NOUN
can-1681	171	15	area	area	NOUN
can-1681	171	16	is	be	AUX
can-1681	171	17	very	very	ADV
can-1681	171	18	large	large	ADJ
can-1681	171	19	,	,	PUNCT
can-1681	171	20	higher	high	ADJ
can-1681	171	21	drug	drug	NOUN
can-1681	171	22	content	content	NOUN
can-1681	171	23	can	can	AUX
can-1681	171	24	be	be	AUX
can-1681	171	25	loaded	load	VERB
can-1681	171	26	in	in	ADP
can-1681	171	27	a	a	DET
can-1681	171	28	very	very	ADV
can-1681	171	29	small	small	ADJ
can-1681	171	30	part	part	NOUN
can-1681	171	31	of[77,78	of[77,78	NOUN
can-1681	171	32	]	]	PUNCT
can-1681	171	33	packages	package	NOUN
can-1681	171	34	.	.	PUNCT
can-1681	172	1	3.10	3.10	NUM
can-1681	172	2	nano	nano	NOUN
can-1681	172	3	preparation	preparation	NOUN
can-1681	172	4	for	for	ADP
can-1681	172	5	treating	treat	VERB
can-1681	172	6	eye	eye	NOUN
can-1681	172	7	diseases	disease	NOUN
can-1681	172	8	most	most	ADJ
can-1681	172	9	ophthalmic	ophthalmic	ADJ
can-1681	172	10	products	product	NOUN
can-1681	172	11	on	on	ADP
can-1681	172	12	the	the	DET
can-1681	172	13	market	market	NOUN
can-1681	172	14	are	be	AUX
can-1681	172	15	topical	topical	ADJ
can-1681	172	16	preparations	preparation	NOUN
can-1681	172	17	for	for	ADP
can-1681	172	18	anterior	anterior	ADJ
can-1681	172	19	administration	administration	NOUN
can-1681	172	20	.	.	PUNCT
can-1681	173	1	the	the	DET
can-1681	173	2	biggest	big	ADJ
can-1681	173	3	disadvantage	disadvantage	NOUN
can-1681	173	4	is	be	AUX
can-1681	173	5	that	that	SCONJ
can-1681	173	6	only	only	ADV
can-1681	173	7	5	5	NUM
can-1681	173	8	%	%	NOUN
can-1681	173	9	of	of	ADP
can-1681	173	10	the	the	DET
can-1681	173	11	injected	inject	VERB
can-1681	173	12	dose	dose	NOUN
can-1681	173	13	reaches	reach	VERB
can-1681	173	14	the	the	DET
can-1681	173	15	anterior	anterior	ADJ
can-1681	173	16	chamber	chamber	NOUN
can-1681	173	17	.	.	PUNCT
can-1681	174	1	also	also	ADV
can-1681	174	2	,	,	PUNCT
can-1681	174	3	the	the	DET
can-1681	174	4	dose	dose	NOUN
can-1681	174	5	penetrating	penetrate	VERB
can-1681	174	6	the	the	DET
can-1681	174	7	posterior	posterior	ADJ
can-1681	174	8	chamber	chamber	NOUN
can-1681	174	9	is	be	AUX
can-1681	174	10	small	small	ADJ
can-1681	174	11	due	due	ADJ
can-1681	174	12	to	to	ADP
can-1681	174	13	multiple	multiple	ADJ
can-1681	174	14	and	and	CCONJ
can-1681	174	15	complex	complex	ADJ
can-1681	174	16	anatomical	anatomical	ADJ
can-1681	174	17	barriers	barrier	NOUN
can-1681	174	18	of	of	ADP
can-1681	174	19	the	the	DET
can-1681	174	20	eyeball	eyeball	NOUN
can-1681	174	21	.	.	PUNCT
can-1681	175	1	nano	nano	NOUN
can-1681	175	2	-	-	PUNCT
can-1681	175	3	sized	sized	ADJ
can-1681	175	4	ophthalmic	ophthalmic	ADJ
can-1681	175	5	drugs	drug	NOUN
can-1681	175	6	(	(	PUNCT
can-1681	175	7	figure	figure	NOUN
can-1681	175	8	1	1	NUM
can-1681	175	9	)	)	PUNCT
can-1681	175	10	have	have	VERB
can-1681	175	11	the	the	DET
can-1681	175	12	advantages	advantage	NOUN
can-1681	175	13	of	of	ADP
can-1681	175	14	good	good	ADJ
can-1681	175	15	solubility	solubility	NOUN
can-1681	175	16	,	,	PUNCT
can-1681	175	17	large	large	ADJ
can-1681	175	18	dissolution	dissolution	NOUN
can-1681	175	19	area	area	NOUN
can-1681	175	20	,	,	PUNCT
can-1681	175	21	fast	fast	ADJ
can-1681	175	22	dissolution	dissolution	NOUN
can-1681	175	23	speed	speed	NOUN
can-1681	175	24	,	,	PUNCT
can-1681	175	25	strong	strong	ADJ
can-1681	175	26	biological	biological	ADJ
can-1681	175	27	adhesion	adhesion	NOUN
can-1681	175	28	,	,	PUNCT
can-1681	175	29	and	and	CCONJ
can-1681	175	30	strong	strong	ADJ
can-1681	175	31	corneal	corneal	ADJ
can-1681	175	32	penetration	penetration	NOUN
can-1681	175	33	.	.	PUNCT
can-1681	176	1	it	it	PRON
can-1681	176	2	is	be	AUX
can-1681	176	3	suggested	suggest	VERB
can-1681	176	4	that	that	SCONJ
can-1681	176	5	the	the	DET
can-1681	176	6	particle	particle	NOUN
can-1681	176	7	size	size	NOUN
can-1681	176	8	should	should	AUX
can-1681	176	9	be	be	AUX
can-1681	176	10	less	less	ADJ
can-1681	176	11	than	than	ADP
can-1681	176	12	10	10	NUM
can-1681	176	13	μm	μm	NOUN
can-1681	176	14	to	to	PART
can-1681	176	15	minimize	minimize	VERB
can-1681	176	16	the	the	DET
can-1681	176	17	irritation	irritation	NOUN
can-1681	176	18	to	to	ADP
can-1681	176	19	the	the	DET
can-1681	176	20	eye	eye	NOUN
can-1681	176	21	structure	structure	NOUN
can-1681	176	22	and	and	CCONJ
can-1681	176	23	reduce	reduce	VERB
can-1681	176	24	the	the	DET
can-1681	176	25	tear	tear	NOUN
can-1681	176	26	and	and	CCONJ
can-1681	176	27	bleeding	bleeding	NOUN
can-1681	176	28	of	of	ADP
can-1681	176	29	the	the	DET
can-1681	176	30	drip	drip	NOUN
can-1681	176	31	dose	dose	NOUN
can-1681	176	32	,	,	PUNCT
can-1681	176	33	so	so	SCONJ
can-1681	176	34	as	as	SCONJ
can-1681	176	35	to	to	PART
can-1681	176	36	improve	improve	VERB
can-1681	176	37	the	the	DET
can-1681	176	38	effectiveness	effectiveness	NOUN
can-1681	176	39	of	of	ADP
can-1681	176	40	eye	eye	NOUN
can-1681	176	41	treatment	treatment	NOUN
can-1681	176	42	.	.	PUNCT
can-1681	177	1	3.11	3.11	NUM
can-1681	177	2	nano	nano	NOUN
can-1681	177	3	suspension	suspension	NOUN
can-1681	177	4	nano	nano	NOUN
can-1681	177	5	suspension	suspension	NOUN
can-1681	177	6	is	be	AUX
can-1681	177	7	a	a	DET
can-1681	177	8	submicron	submicron	NOUN
can-1681	177	9	colloidal	colloidal	NOUN
can-1681	177	10	dispersion	dispersion	NOUN
can-1681	177	11	of	of	ADP
can-1681	177	12	pure	pure	ADJ
can-1681	177	13	drug	drug	NOUN
can-1681	177	14	particles	particle	NOUN
can-1681	177	15	in	in	ADP
can-1681	177	16	the	the	DET
can-1681	177	17	external	external	ADJ
can-1681	177	18	liquid	liquid	ADJ
can-1681	177	19	phase	phase	NOUN
can-1681	177	20	.	.	PUNCT
can-1681	178	1	an	an	DET
can-1681	178	2	important	important	ADJ
can-1681	178	3	feature	feature	NOUN
can-1681	178	4	of	of	ADP
can-1681	178	5	nanosuspension	nanosuspension	NOUN
can-1681	178	6	is	be	AUX
can-1681	178	7	to	to	PART
can-1681	178	8	increase	increase	VERB
can-1681	178	9	the	the	DET
can-1681	178	10	saturated	saturate	VERB
can-1681	178	11	solubility	solubility	NOUN
can-1681	178	12	,	,	PUNCT
can-1681	178	13	so	so	SCONJ
can-1681	178	14	as	as	SCONJ
can-1681	178	15	to	to	PART
can-1681	178	16	improve	improve	VERB
can-1681	178	17	the	the	DET
can-1681	178	18	dissolution	dissolution	NOUN
can-1681	178	19	rate	rate	NOUN
can-1681	178	20	of	of	ADP
can-1681	178	21	compounds	compound	NOUN
can-1681	178	22	.	.	PUNCT
can-1681	179	1	in	in	ADP
can-1681	179	2	this	this	DET
can-1681	179	3	system	system	NOUN
can-1681	179	4	,	,	PUNCT
can-1681	179	5	the	the	DET
can-1681	179	6	drug	drug	NOUN
can-1681	179	7	is	be	AUX
can-1681	179	8	bound	bind	VERB
can-1681	179	9	or	or	CCONJ
can-1681	179	10	dissolved	dissolve	VERB
can-1681	179	11	in	in	ADP
can-1681	179	12	the	the	DET
can-1681	179	13	structure	structure	NOUN
can-1681	179	14	,	,	PUNCT
can-1681	179	15	encapsulated	encapsulate	VERB
can-1681	179	16	or	or	CCONJ
can-1681	179	17	captured	capture	VERB
can-1681	179	18	in	in	ADP
can-1681	179	19	the	the	DET
can-1681	179	20	structure	structure	NOUN
can-1681	179	21	by	by	ADP
can-1681	179	22	binding	bind	VERB
can-1681	179	23	to	to	ADP
can-1681	179	24	the	the	DET
can-1681	179	25	matrix	matrix	NOUN
can-1681	179	26	,	,	PUNCT
can-1681	179	27	and	and	CCONJ
can-1681	179	28	a	a	DET
can-1681	179	29	general	general	ADJ
can-1681	179	30	drug	drug	NOUN
can-1681	179	31	delivery	delivery	NOUN
can-1681	179	32	system	system	NOUN
can-1681	179	33	is	be	AUX
can-1681	179	34	generated	generate	VERB
can-1681	179	35	,	,	PUNCT
can-1681	179	36	including	include	VERB
can-1681	179	37	microemulsion	microemulsion	NOUN
can-1681	179	38	,	,	PUNCT
can-1681	179	39	liposome	liposome	NOUN
can-1681	179	40	,	,	PUNCT
can-1681	179	41	niosomes	niosome	NOUN
can-1681	179	42	,	,	PUNCT
can-1681	179	43	dendrimer	dendrimer	NOUN
can-1681	179	44	,	,	PUNCT
can-1681	179	45	and	and	CCONJ
can-1681	179	46	cyclodextrin[79,80	cyclodextrin[79,80	NOUN
can-1681	179	47	]	]	PUNCT
can-1681	179	48	.	.	PUNCT
can-1681	180	1	advantages	advantage	NOUN
can-1681	180	2	of	of	ADP
can-1681	180	3	using	use	VERB
can-1681	180	4	nanoparticles	nanoparticle	NOUN
can-1681	180	5	include	include	VERB
can-1681	180	6	improved	improve	VERB
can-1681	180	7	local	local	ADJ
can-1681	180	8	delivery	delivery	NOUN
can-1681	180	9	of	of	ADP
can-1681	180	10	macromolecules	macromolecule	NOUN
can-1681	180	11	and	and	CCONJ
can-1681	180	12	low	low	ADJ
can-1681	180	13	water	water	NOUN
can-1681	180	14	-	-	PUNCT
can-1681	180	15	soluble	soluble	ADJ
can-1681	180	16	molecules	molecule	NOUN
can-1681	180	17	,	,	PUNCT
can-1681	180	18	such	such	ADJ
can-1681	180	19	as	as	ADP
can-1681	180	20	glucocorticoids	glucocorticoid	NOUN
can-1681	180	21	or	or	CCONJ
can-1681	180	22	cyclosporine	cyclosporine	NOUN
can-1681	180	23	,	,	PUNCT
can-1681	180	24	for	for	ADP
can-1681	180	25	the	the	DET
can-1681	180	26	treatment	treatment	NOUN
can-1681	180	27	of	of	ADP
can-1681	180	28	immune	immune	ADJ
can-1681	180	29	diseases	disease	NOUN
can-1681	180	30	affecting	affect	VERB
can-1681	180	31	vision[81	vision[81	NOUN
can-1681	180	32	]	]	PUNCT
can-1681	180	33	.	.	PUNCT
can-1681	181	1	other	other	ADJ
can-1681	181	2	unstable	unstable	ADJ
can-1681	181	3	macromolecules	macromolecule	NOUN
can-1681	181	4	,	,	PUNCT
can-1681	181	5	such	such	ADJ
can-1681	181	6	as	as	ADP
can-1681	181	7	nucleic	nucleic	ADJ
can-1681	181	8	acids	acid	NOUN
can-1681	181	9	,	,	PUNCT
can-1681	181	10	are	be	AUX
can-1681	181	11	administered	administer	VERB
can-1681	181	12	through	through	ADP
can-1681	181	13	nanoparticles	nanoparticle	NOUN
can-1681	181	14	,	,	PUNCT
can-1681	181	15	providing	provide	VERB
can-1681	181	16	promising	promising	ADJ
can-1681	181	17	results	result	NOUN
can-1681	181	18	for	for	ADP
can-1681	181	19	gene	gene	NOUN
can-1681	181	20	transfer	transfer	NOUN
can-1681	181	21	in	in	ADP
can-1681	181	22	the	the	DET
can-1681	181	23	treatment	treatment	NOUN
can-1681	181	24	of	of	ADP
can-1681	181	25	retinopathy[82,83	retinopathy[82,83	NOUN
can-1681	181	26	]	]	PUNCT
can-1681	181	27	.	.	PUNCT
can-1681	182	1	nanoparticle	nanoparticle	NOUN
can-1681	182	2	-	-	PUNCT
can-1681	182	3	mediated	mediate	VERB
can-1681	182	4	drug	drug	NOUN
can-1681	182	5	delivery	delivery	NOUN
can-1681	182	6	increases	increase	VERB
can-1681	182	7	the	the	DET
can-1681	182	8	contact	contact	NOUN
can-1681	182	9	time	time	NOUN
can-1681	182	10	between	between	ADP
can-1681	182	11	the	the	DET
can-1681	182	12	administered	administer	VERB
can-1681	182	13	drug	drug	NOUN
can-1681	182	14	and	and	CCONJ
can-1681	182	15	the	the	DET
can-1681	182	16	target	target	NOUN
can-1681	182	17	tissue	tissue	NOUN
can-1681	182	18	,	,	PUNCT
can-1681	182	19	such	such	ADJ
can-1681	182	20	as	as	ADP
can-1681	182	21	brimonidine	brimonidine	NOUN
can-1681	182	22	,	,	PUNCT
can-1681	182	23	one	one	NUM
can-1681	182	24	of	of	ADP
can-1681	182	25	the	the	DET
can-1681	182	26	traditional	traditional	ADJ
can-1681	182	27	glaucoma	glaucoma	NOUN
can-1681	182	28	treatment	treatment	NOUN
can-1681	182	29	methods	method	NOUN
can-1681	182	30	,	,	PUNCT
can-1681	182	31	or	or	CCONJ
can-1681	182	32	corticosteroids	corticosteroid	NOUN
can-1681	182	33	for	for	ADP
can-1681	182	34	the	the	DET
can-1681	182	35	treatment	treatment	NOUN
can-1681	182	36	of	of	ADP
can-1681	182	37	autoimmune	autoimmune	NOUN
can-1681	182	38	uveitis[78,84	uveitis[78,84	ADJ
can-1681	182	39	]	]	PUNCT
can-1681	182	40	.	.	PUNCT
can-1681	183	1	some	some	DET
can-1681	183	2	nano	nano	NOUN
can-1681	183	3	-	-	PUNCT
can-1681	183	4	formulations	formulation	NOUN
can-1681	183	5	allow	allow	VERB
can-1681	183	6	the	the	DET
can-1681	183	7	nonsteroidal	nonsteroidal	NOUN
can-1681	183	8	anti	anti	ADJ
can-1681	183	9	-	-	ADJ
can-1681	183	10	inflammatory	inflammatory	ADJ
can-1681	183	11	drug	drug	NOUN
can-1681	183	12	indomethacin	indomethacin	VERB
can-1681	183	13	to	to	PART
can-1681	183	14	reach	reach	VERB
can-1681	183	15	the	the	DET
can-1681	183	16	posterior	posterior	ADJ
can-1681	183	17	internal	internal	ADJ
can-1681	183	18	structure	structure	NOUN
can-1681	183	19	of	of	ADP
can-1681	183	20	the	the	DET
can-1681	183	21	eye	eye	NOUN
can-1681	183	22	through	through	ADP
can-1681	183	23	a	a	DET
can-1681	183	24	transmucosal	transmucosal	NOUN
can-1681	183	25	pathway[85	pathway[85	NOUN
can-1681	183	26	]	]	PUNCT
can-1681	183	27	.	.	PUNCT
can-1681	184	1	new	new	ADJ
can-1681	184	2	applications	application	NOUN
can-1681	184	3	include	include	VERB
can-1681	184	4	the	the	DET
can-1681	184	5	use	use	NOUN
can-1681	184	6	of	of	ADP
can-1681	184	7	gold	gold	ADJ
can-1681	184	8	nanoparticles	nanoparticle	NOUN
can-1681	184	9	to	to	PART
can-1681	184	10	make	make	VERB
can-1681	184	11	the	the	DET
can-1681	184	12	possibility	possibility	NOUN
can-1681	184	13	of	of	ADP
can-1681	184	14	targeted	target	VERB
can-1681	184	15	drug	drug	NOUN
can-1681	184	16	delivery	delivery	NOUN
can-1681	184	17	reach	reach	VERB
can-1681	184	18	specific	specific	ADJ
can-1681	184	19	types	type	NOUN
can-1681	184	20	of	of	ADP
can-1681	184	21	cancer	cancer	NOUN
can-1681	184	22	,	,	PUNCT
can-1681	184	23	such	such	ADJ
can-1681	184	24	as	as	ADP
can-1681	184	25	choroidal	choroidal	ADJ
can-1681	184	26	melanoma	melanoma	NOUN
can-1681	184	27	,	,	PUNCT
can-1681	184	28	and	and	CCONJ
can-1681	184	29	keep	keep	VERB
can-1681	184	30	normal	normal	ADJ
can-1681	184	31	cells	cell	NOUN
can-1681	184	32	intact[86	intact[86	VERB
can-1681	184	33	]	]	PUNCT
can-1681	184	34	.	.	PUNCT
can-1681	185	1	3.12	3.12	NUM
can-1681	185	2	contact	contact	NOUN
can-1681	185	3	lenses	lense	NOUN
can-1681	185	4	contact	contact	NOUN
can-1681	185	5	lenses	lense	NOUN
can-1681	185	6	are	be	AUX
can-1681	185	7	hard	hard	ADJ
can-1681	185	8	or	or	CCONJ
can-1681	185	9	soft	soft	ADJ
can-1681	185	10	polymer	polymer	NOUN
can-1681	185	11	devices	device	NOUN
can-1681	185	12	designed	design	VERB
can-1681	185	13	to	to	PART
can-1681	185	14	directly	directly	ADV
can-1681	185	15	adapt	adapt	VERB
can-1681	185	16	to	to	ADP
can-1681	185	17	the	the	DET
can-1681	185	18	cornea	cornea	NOUN
can-1681	185	19	to	to	PART
can-1681	185	20	correct	correct	VERB
can-1681	185	21	refractive	refractive	ADJ
can-1681	185	22	abnormalities	abnormality	NOUN
can-1681	185	23	.	.	PUNCT
can-1681	186	1	in	in	ADP
can-1681	186	2	1965	1965	NUM
can-1681	186	3	,	,	PUNCT
can-1681	186	4	wichterle	wichterle	VERB
can-1681	186	5	et	et	PROPN
can-1681	186	6	al.[87	al.[87	PROPN
can-1681	186	7	]	]	PUNCT
can-1681	186	8	patented	patent	VERB
can-1681	186	9	the	the	DET
can-1681	186	10	idea	idea	NOUN
can-1681	186	11	of	of	ADP
can-1681	186	12	using	use	VERB
can-1681	186	13	hydrogel	hydrogel	NOUN
can-1681	186	14	contact	contact	NOUN
can-1681	186	15	lenses	lense	NOUN
can-1681	186	16	as	as	ADP
can-1681	186	17	drug	drug	NOUN
can-1681	186	18	delivery	delivery	NOUN
can-1681	186	19	devices	device	NOUN
can-1681	186	20	.	.	PUNCT
can-1681	187	1	the	the	DET
can-1681	187	2	patent	patent	NOUN
can-1681	187	3	refers	refer	VERB
can-1681	187	4	to	to	ADP
can-1681	187	5	the	the	DET
can-1681	187	6	inclusion	inclusion	NOUN
can-1681	187	7	of	of	ADP
can-1681	187	8	drugs	drug	NOUN
can-1681	187	9	in	in	ADP
can-1681	187	10	the	the	DET
can-1681	187	11	lens	lens	NOUN
can-1681	187	12	hydration	hydration	NOUN
can-1681	187	13	process	process	NOUN
can-1681	187	14	to	to	PART
can-1681	187	15	provide	provide	VERB
can-1681	187	16	higher	high	ADJ
can-1681	187	17	drug	drug	NOUN
can-1681	187	18	availability	availability	NOUN
can-1681	187	19	in	in	ADP
can-1681	187	20	use	use	NOUN
can-1681	187	21	.	.	PUNCT
can-1681	188	1	wrapping	wrap	VERB
can-1681	188	2	drug	drug	NOUN
can-1681	188	3	-	-	PUNCT
can-1681	188	4	loaded	load	VERB
can-1681	188	5	nanoparticles	nanoparticle	NOUN
can-1681	188	6	in	in	ADP
can-1681	188	7	the	the	DET
can-1681	188	8	polymer	polymer	NOUN
can-1681	188	9	matrix	matrix	NOUN
can-1681	188	10	of	of	ADP
can-1681	188	11	contact	contact	NOUN
can-1681	188	12	lenses	lense	NOUN
can-1681	188	13	is	be	AUX
can-1681	188	14	an	an	DET
can-1681	188	15	effective	effective	ADJ
can-1681	188	16	strategy	strategy	NOUN
can-1681	188	17	to	to	PART
can-1681	188	18	prolong	prolong	VERB
can-1681	188	19	drug	drug	NOUN
can-1681	188	20	delivery	delivery	NOUN
can-1681	188	21	.	.	PUNCT
can-1681	189	1	the	the	DET
can-1681	189	2	incorporation	incorporation	NOUN
can-1681	189	3	of	of	ADP
can-1681	189	4	drugs	drug	NOUN
can-1681	189	5	is	be	AUX
can-1681	189	6	achieved	achieve	VERB
can-1681	189	7	by	by	ADP
can-1681	189	8	printing	print	VERB
can-1681	189	9	,	,	PUNCT
can-1681	189	10	simple	simple	ADJ
can-1681	189	11	immersion	immersion	NOUN
can-1681	189	12	,	,	PUNCT
can-1681	189	13	and	and	CCONJ
can-1681	189	14	colloidal	colloidal	NOUN
can-1681	189	15	nanoparticles[88–90	nanoparticles[88–90	NOUN
can-1681	189	16	]	]	PUNCT
can-1681	189	17	.	.	PUNCT
can-1681	190	1	the	the	DET
can-1681	190	2	diameter	diameter	NOUN
can-1681	190	3	of	of	ADP
can-1681	190	4	nanoparticles	nanoparticle	NOUN
can-1681	190	5	must	must	AUX
can-1681	190	6	be	be	AUX
can-1681	190	7	very	very	ADV
can-1681	190	8	small	small	ADJ
can-1681	190	9	and	and	CCONJ
can-1681	190	10	used	use	VERB
can-1681	190	11	in	in	ADP
can-1681	190	12	contact	contact	NOUN
can-1681	190	13	lenses	lense	NOUN
can-1681	190	14	to	to	PART
can-1681	190	15	prevent	prevent	VERB
can-1681	190	16	particles	particle	NOUN
can-1681	190	17	from	from	ADP
can-1681	190	18	hindering	hinder	VERB
can-1681	190	19	users	user	NOUN
can-1681	190	20	’	’	PART
can-1681	190	21	vision	vision	NOUN
can-1681	190	22	.	.	PUNCT
can-1681	191	1	therefore	therefore	ADV
can-1681	191	2	,	,	PUNCT
can-1681	191	3	it	it	PRON
can-1681	191	4	is	be	AUX
can-1681	191	5	necessary	necessary	ADJ
can-1681	191	6	to	to	PART
can-1681	191	7	delay	delay	VERB
can-1681	191	8	the	the	DET
can-1681	191	9	release	release	NOUN
can-1681	191	10	of	of	ADP
can-1681	191	11	drugs	drug	NOUN
can-1681	191	12	in	in	ADP
can-1681	191	13	other	other	ADJ
can-1681	191	14	ways	way	NOUN
can-1681	191	15	.	.	PUNCT
can-1681	192	1	this	this	PRON
can-1681	192	2	can	can	AUX
can-1681	192	3	be	be	AUX
can-1681	192	4	achieved	achieve	VERB
can-1681	192	5	by	by	ADP
can-1681	192	6	combining	combine	VERB
can-1681	192	7	the	the	DET
can-1681	192	8	drug	drug	NOUN
can-1681	192	9	with	with	ADP
can-1681	192	10	the	the	DET
can-1681	192	11	particles	particle	NOUN
can-1681	192	12	or	or	CCONJ
can-1681	192	13	dispersing	disperse	VERB
can-1681	192	14	the	the	DET
can-1681	192	15	particles	particle	NOUN
can-1681	192	16	through	through	ADP
can-1681	192	17	separable	separable	ADJ
can-1681	192	18	chemical	chemical	NOUN
can-1681	192	19	bonds	bond	NOUN
can-1681	192	20	so	so	SCONJ
can-1681	192	21	that	that	SCONJ
can-1681	192	22	the	the	DET
can-1681	192	23	affinity	affinity	NOUN
can-1681	192	24	of	of	ADP
can-1681	192	25	the	the	DET
can-1681	192	26	drug	drug	NOUN
can-1681	192	27	to	to	ADP
can-1681	192	28	the	the	DET
can-1681	192	29	particles	particle	NOUN
can-1681	192	30	is	be	AUX
can-1681	192	31	greater	great	ADJ
can-1681	192	32	73	73	NUM
can-1681	192	33	than	than	ADP
can-1681	192	34	that	that	PRON
can-1681	192	35	to	to	ADP
can-1681	192	36	the	the	DET
can-1681	192	37	surrounding	surround	VERB
can-1681	192	38	lens	lens	NOUN
can-1681	192	39	material[89	material[89	NOUN
can-1681	192	40	]	]	PUNCT
can-1681	192	41	.	.	PUNCT
can-1681	193	1	this	this	DET
can-1681	193	2	method	method	NOUN
can-1681	193	3	allows	allow	VERB
can-1681	193	4	the	the	DET
can-1681	193	5	sustainable	sustainable	ADJ
can-1681	193	6	release	release	NOUN
can-1681	193	7	of	of	ADP
can-1681	193	8	drugs	drug	NOUN
can-1681	193	9	,	,	PUNCT
can-1681	193	10	which	which	PRON
can-1681	193	11	can	can	AUX
can-1681	193	12	be	be	AUX
can-1681	193	13	adjusted	adjust	VERB
can-1681	193	14	from	from	ADP
can-1681	193	15	hours	hour	NOUN
can-1681	193	16	to	to	ADP
can-1681	193	17	weeks	week	NOUN
can-1681	193	18	according	accord	VERB
can-1681	193	19	to	to	ADP
can-1681	193	20	the	the	DET
can-1681	193	21	needs	need	NOUN
can-1681	193	22	of	of	ADP
can-1681	193	23	patients	patient	NOUN
can-1681	193	24	,	,	PUNCT
can-1681	193	25	and	and	CCONJ
can-1681	193	26	allows	allow	VERB
can-1681	193	27	the	the	DET
can-1681	193	28	treatment	treatment	NOUN
can-1681	193	29	of	of	ADP
can-1681	193	30	anterior	anterior	ADJ
can-1681	193	31	segment	segment	NOUN
can-1681	193	32	lesions	lesion	NOUN
can-1681	193	33	.	.	PUNCT
can-1681	194	1	different	different	ADJ
can-1681	194	2	nanoparticles	nanoparticle	NOUN
can-1681	194	3	,	,	PUNCT
can-1681	194	4	lead	lead	VERB
can-1681	194	5	liposomes	liposome	NOUN
can-1681	194	6	and	and	CCONJ
can-1681	194	7	microemulsions	microemulsion	NOUN
can-1681	194	8	have	have	AUX
can-1681	194	9	been	be	AUX
can-1681	194	10	patented	patent	VERB
can-1681	194	11	,	,	PUNCT
can-1681	194	12	which	which	PRON
can-1681	194	13	contain	contain	VERB
can-1681	194	14	pharmaceutical	pharmaceutical	ADJ
can-1681	194	15	products	product	NOUN
can-1681	194	16	and	and	CCONJ
can-1681	194	17	then	then	ADV
can-1681	194	18	loaded	load	VERB
can-1681	194	19	into	into	ADP
can-1681	194	20	contact	contact	NOUN
can-1681	194	21	lenses	lense	NOUN
can-1681	194	22	.	.	PUNCT
can-1681	195	1	liposomes	liposome	NOUN
can-1681	195	2	are	be	AUX
can-1681	195	3	used	use	VERB
can-1681	195	4	in	in	ADP
can-1681	195	5	various	various	ADJ
can-1681	195	6	drug	drug	NOUN
can-1681	195	7	delivery	delivery	NOUN
can-1681	195	8	applications	application	NOUN
can-1681	195	9	due	due	ADP
can-1681	195	10	to	to	ADP
can-1681	195	11	their	their	PRON
can-1681	195	12	high	high	ADJ
can-1681	195	13	biocompatibility	biocompatibility	NOUN
can-1681	195	14	,	,	PUNCT
can-1681	195	15	transparent	transparent	ADJ
can-1681	195	16	permanent	permanent	ADJ
can-1681	195	17	lens	len	NOUN
can-1681	195	18	,	,	PUNCT
can-1681	195	19	and	and	CCONJ
can-1681	195	20	several	several	ADJ
can-1681	195	21	days	day	NOUN
can-1681	195	22	of	of	ADP
can-1681	195	23	drug	drug	NOUN
can-1681	195	24	release	release	NOUN
can-1681	195	25	.	.	PUNCT
can-1681	196	1	the	the	DET
can-1681	196	2	initial	initial	ADJ
can-1681	196	3	release	release	NOUN
can-1681	196	4	is	be	AUX
can-1681	196	5	due	due	ADJ
can-1681	196	6	to	to	ADP
can-1681	196	7	the	the	DET
can-1681	196	8	unpackaged	unpackaged	ADJ
can-1681	196	9	drug	drug	NOUN
can-1681	196	10	in	in	ADP
can-1681	196	11	the	the	DET
can-1681	196	12	lens	len	NOUN
can-1681	196	13	.	.	PUNCT
can-1681	197	1	contact	contact	NOUN
can-1681	197	2	lenses	lense	NOUN
can-1681	197	3	loaded	load	VERB
can-1681	197	4	with	with	ADP
can-1681	197	5	releasing	release	VERB
can-1681	197	6	microemulsion	microemulsion	NOUN
can-1681	197	7	will	will	AUX
can-1681	197	8	be	be	AUX
can-1681	197	9	administered	administer	VERB
can-1681	197	10	for	for	ADP
can-1681	197	11	4–8	4–8	NUM
can-1681	197	12	days	day	NOUN
can-1681	197	13	,	,	PUNCT
can-1681	197	14	and	and	CCONJ
can-1681	197	15	the	the	DET
can-1681	197	16	initial	initial	ADJ
can-1681	197	17	peak	peak	NOUN
can-1681	197	18	is	be	AUX
can-1681	197	19	attributed	attribute	VERB
can-1681	197	20	to	to	ADP
can-1681	197	21	the	the	DET
can-1681	197	22	unpackaged	unpackaged	ADJ
can-1681	197	23	drug[89	drug[89	NOUN
can-1681	197	24	]	]	PUNCT
can-1681	197	25	.	.	PUNCT
can-1681	198	1	in	in	ADP
can-1681	198	2	2013	2013	NUM
can-1681	198	3	,	,	PUNCT
can-1681	198	4	jung	jung	PROPN
can-1681	198	5	et	et	PROPN
can-1681	198	6	al	al	PROPN
can-1681	198	7	.	.	PROPN
can-1681	198	8	dispersed	disperse	VERB
can-1681	198	9	timolol	timolol	NOUN
can-1681	198	10	nanoparticles	nanoparticle	NOUN
can-1681	198	11	in	in	ADP
can-1681	198	12	silica	silica	NOUN
can-1681	198	13	gel	gel	NOUN
can-1681	198	14	contact	contact	NOUN
can-1681	198	15	lenses	lense	NOUN
can-1681	198	16	for	for	ADP
can-1681	198	17	30	30	NUM
can-1681	198	18	days	day	NOUN
can-1681	198	19	.	.	PUNCT
can-1681	199	1	preliminary	preliminary	ADJ
can-1681	199	2	studies	study	NOUN
can-1681	199	3	in	in	ADP
can-1681	199	4	beagle	beagle	NOUN
can-1681	199	5	dogs	dog	NOUN
can-1681	199	6	have	have	AUX
can-1681	199	7	shown	show	VERB
can-1681	199	8	promising	promising	ADJ
can-1681	199	9	results	result	NOUN
can-1681	199	10	in	in	ADP
can-1681	199	11	treating	treat	VERB
can-1681	199	12	glaucoma	glaucoma	NOUN
can-1681	199	13	.	.	PUNCT
can-1681	200	1	the	the	DET
can-1681	200	2	incorporation	incorporation	NOUN
can-1681	200	3	of	of	ADP
can-1681	200	4	nanoparticles	nanoparticle	NOUN
can-1681	200	5	into	into	ADP
can-1681	200	6	silicon	silicon	NOUN
can-1681	200	7	hydrogels	hydrogel	NOUN
can-1681	200	8	leads	lead	VERB
can-1681	200	9	to	to	ADP
can-1681	200	10	the	the	DET
can-1681	200	11	decrease	decrease	NOUN
can-1681	200	12	of	of	ADP
can-1681	200	13	ion	ion	NOUN
can-1681	200	14	and	and	CCONJ
can-1681	200	15	oxygen	oxygen	NOUN
can-1681	200	16	permeability	permeability	NOUN
can-1681	200	17	and	and	CCONJ
can-1681	200	18	the	the	DET
can-1681	200	19	increase	increase	NOUN
can-1681	200	20	of	of	ADP
can-1681	200	21	modulus	modulus	NOUN
can-1681	200	22	.	.	PUNCT
can-1681	201	1	the	the	DET
can-1681	201	2	impact	impact	NOUN
can-1681	201	3	on	on	ADP
can-1681	201	4	each	each	DET
can-1681	201	5	precursor	precursor	NOUN
can-1681	201	6	is	be	AUX
can-1681	201	7	directly	directly	ADV
can-1681	201	8	proportional	proportional	ADJ
can-1681	201	9	to	to	ADP
can-1681	201	10	the	the	DET
can-1681	201	11	charge	charge	NOUN
can-1681	201	12	of	of	ADP
can-1681	201	13	particles[74	particles[74	PROPN
can-1681	201	14	]	]	PUNCT
can-1681	201	15	.	.	PUNCT
can-1681	202	1	in	in	ADP
can-1681	202	2	2018	2018	NUM
can-1681	202	3	,	,	PUNCT
can-1681	202	4	maulvi	maulvi	PROPN
can-1681	202	5	et	et	PROPN
can-1681	202	6	al	al	PROPN
can-1681	202	7	.	.	PROPN
can-1681	202	8	added	add	VERB
can-1681	202	9	gold	gold	NOUN
can-1681	202	10	nanoparticles	nanoparticle	NOUN
can-1681	202	11	into	into	ADP
can-1681	202	12	contact	contact	NOUN
can-1681	202	13	lenses	lense	NOUN
can-1681	202	14	to	to	PART
can-1681	202	15	improve	improve	VERB
can-1681	202	16	the	the	DET
can-1681	202	17	absorption	absorption	NOUN
can-1681	202	18	of	of	ADP
can-1681	202	19	timolol	timolol	NOUN
can-1681	202	20	from	from	ADP
can-1681	202	21	drug	drug	NOUN
can-1681	202	22	solvent	solvent	NOUN
can-1681	202	23	solution	solution	NOUN
can-1681	202	24	,	,	PUNCT
can-1681	202	25	and	and	CCONJ
can-1681	202	26	obtained	obtain	VERB
can-1681	202	27	satisfactory	satisfactory	ADJ
can-1681	202	28	release	release	NOUN
can-1681	202	29	kinetics	kinetic	NOUN
can-1681	202	30	in	in	ADP
can-1681	202	31	vivo	vivo	NOUN
can-1681	202	32	,	,	PUNCT
can-1681	202	33	while	while	SCONJ
can-1681	202	34	maintaining	maintain	VERB
can-1681	202	35	the	the	DET
can-1681	202	36	characteristics	characteristic	NOUN
can-1681	202	37	of	of	ADP
can-1681	202	38	contact	contact	NOUN
can-1681	202	39	lenses[91	lenses[91	X
can-1681	202	40	]	]	PUNCT
can-1681	202	41	.	.	PUNCT
can-1681	203	1	the	the	DET
can-1681	203	2	device	device	NOUN
can-1681	203	3	studied	study	VERB
can-1681	203	4	has	have	VERB
can-1681	203	5	excellent	excellent	ADJ
can-1681	203	6	mechanical	mechanical	ADJ
can-1681	203	7	properties	property	NOUN
can-1681	203	8	,	,	PUNCT
can-1681	203	9	and	and	CCONJ
can-1681	203	10	the	the	DET
can-1681	203	11	researchers	researcher	NOUN
can-1681	203	12	believe	believe	VERB
can-1681	203	13	that	that	SCONJ
can-1681	203	14	this	this	DET
can-1681	203	15	material	material	NOUN
can-1681	203	16	is	be	AUX
can-1681	203	17	suitable	suitable	ADJ
can-1681	203	18	for	for	ADP
can-1681	203	19	administration	administration	NOUN
can-1681	203	20	from	from	ADP
can-1681	203	21	daily	daily	ADJ
can-1681	203	22	reusable	reusable	ADJ
can-1681	203	23	contact	contact	NOUN
can-1681	203	24	lenses	lense	NOUN
can-1681	203	25	.	.	PUNCT
can-1681	204	1	3.13	3.13	NUM
can-1681	204	2	intraocular	intraocular	ADJ
can-1681	204	3	implant	implant	ADJ
can-1681	204	4	ocular	ocular	ADJ
can-1681	204	5	implants	implant	NOUN
can-1681	204	6	are	be	AUX
can-1681	204	7	a	a	DET
can-1681	204	8	new	new	ADJ
can-1681	204	9	treatment	treatment	NOUN
can-1681	204	10	method	method	NOUN
can-1681	204	11	for	for	ADP
can-1681	204	12	the	the	DET
can-1681	204	13	controlled	control	VERB
can-1681	204	14	release	release	NOUN
can-1681	204	15	of	of	ADP
can-1681	204	16	drugs	drug	NOUN
can-1681	204	17	by	by	ADP
can-1681	204	18	reducing	reduce	VERB
can-1681	204	19	the	the	DET
can-1681	204	20	dose	dose	NOUN
can-1681	204	21	and	and	CCONJ
can-1681	204	22	increasing	increase	VERB
can-1681	204	23	the	the	DET
can-1681	204	24	drug	drug	NOUN
can-1681	204	25	load	load	NOUN
can-1681	204	26	.	.	PUNCT
can-1681	205	1	in	in	ADP
can-1681	205	2	addition	addition	NOUN
can-1681	205	3	,	,	PUNCT
can-1681	205	4	the	the	DET
can-1681	205	5	systemic	systemic	ADJ
can-1681	205	6	side	side	NOUN
can-1681	205	7	effects	effect	NOUN
can-1681	205	8	are	be	AUX
can-1681	205	9	lesser	less	ADJ
can-1681	205	10	and	and	CCONJ
can-1681	205	11	closer	close	ADJ
can-1681	205	12	to	to	ADP
can-1681	205	13	the	the	DET
can-1681	205	14	target	target	NOUN
can-1681	205	15	site	site	NOUN
can-1681	205	16	,	,	PUNCT
can-1681	205	17	namely	namely	ADV
can-1681	205	18	the	the	DET
can-1681	205	19	posterior	posterior	ADJ
can-1681	205	20	segment	segment	NOUN
can-1681	205	21	of	of	ADP
can-1681	205	22	the	the	DET
can-1681	205	23	eye	eye	NOUN
can-1681	205	24	.	.	PUNCT
can-1681	206	1	biodegradable	biodegradable	ADJ
can-1681	206	2	or	or	CCONJ
can-1681	206	3	non	non	ADJ
can-1681	206	4	-	-	ADJ
can-1681	206	5	biodegradable	biodegradable	ADJ
can-1681	206	6	polymers	polymer	NOUN
can-1681	206	7	can	can	AUX
can-1681	206	8	be	be	AUX
can-1681	206	9	used	use	VERB
can-1681	206	10	in	in	ADP
can-1681	206	11	eye	eye	NOUN
can-1681	206	12	implant	implant	ADJ
can-1681	206	13	systems	system	NOUN
can-1681	206	14	.	.	PUNCT
can-1681	207	1	although	although	SCONJ
can-1681	207	2	biodegradable	biodegradable	ADJ
can-1681	207	3	implants	implant	NOUN
can-1681	207	4	do	do	AUX
can-1681	207	5	not	not	PART
can-1681	207	6	need	need	VERB
can-1681	207	7	to	to	PART
can-1681	207	8	be	be	AUX
can-1681	207	9	removed	remove	VERB
can-1681	207	10	after	after	ADP
can-1681	207	11	implantation	implantation	NOUN
can-1681	207	12	into	into	ADP
can-1681	207	13	the	the	DET
can-1681	207	14	eye	eye	NOUN
can-1681	207	15	,	,	PUNCT
can-1681	207	16	non	non	ADJ
can-1681	207	17	-	-	ADJ
can-1681	207	18	biodegradable	biodegradable	ADJ
can-1681	207	19	implants	implant	NOUN
can-1681	207	20	require	require	VERB
can-1681	207	21	additional	additional	ADJ
can-1681	207	22	intervention	intervention	NOUN
can-1681	207	23	to	to	PART
can-1681	207	24	remove	remove	VERB
can-1681	207	25	or	or	CCONJ
can-1681	207	26	fill	fill	VERB
can-1681	207	27	the	the	DET
can-1681	207	28	implant	implant	NOUN
can-1681	207	29	,	,	PUNCT
can-1681	207	30	which	which	PRON
can-1681	207	31	brings	bring	VERB
can-1681	207	32	additional	additional	ADJ
can-1681	207	33	costs	cost	NOUN
can-1681	207	34	and	and	CCONJ
can-1681	207	35	intraoperative	intraoperative	ADJ
can-1681	207	36	or	or	CCONJ
can-1681	207	37	postoperative	postoperative	ADJ
can-1681	207	38	surgical	surgical	ADJ
can-1681	207	39	risks	risk	NOUN
can-1681	207	40	.	.	PUNCT
can-1681	208	1	the	the	DET
can-1681	208	2	latest	late	ADJ
can-1681	208	3	development	development	NOUN
can-1681	208	4	of	of	ADP
can-1681	208	5	a	a	DET
can-1681	208	6	biodegradable	biodegradable	ADJ
can-1681	208	7	implant	implant	ADJ
can-1681	208	8	system	system	NOUN
can-1681	208	9	is	be	AUX
can-1681	208	10	the	the	DET
can-1681	208	11	env705	env705	PROPN
can-1681	208	12	™	™	ADJ
can-1681	208	13	implant	implant	ADJ
can-1681	208	14	envisia	envisia	ADJ
can-1681	208	15	therapeutic	therapeutic	ADJ
can-1681	208	16	agent	agent	NOUN
can-1681	208	17	and	and	CCONJ
can-1681	208	18	zordera[92	zordera[92	NOUN
can-1681	208	19	]	]	X
can-1681	208	20	nanoporous	nanoporous	ADJ
can-1681	208	21	membrane	membrane	NOUN
can-1681	208	22	device	device	NOUN
can-1681	208	23	.	.	PUNCT
can-1681	209	1	the	the	DET
can-1681	209	2	invention	invention	NOUN
can-1681	209	3	discloses	disclose	VERB
can-1681	209	4	a	a	DET
can-1681	209	5	nanoporous	nanoporous	ADJ
can-1681	209	6	membrane	membrane	NOUN
can-1681	209	7	skunk	skunk	NOUN
can-1681	209	8	device	device	NOUN
can-1681	209	9	,	,	PUNCT
can-1681	209	10	which	which	PRON
can-1681	209	11	comprises	comprise	VERB
can-1681	209	12	two	two	NUM
can-1681	209	13	layers	layer	NOUN
can-1681	209	14	of	of	ADP
can-1681	209	15	biodegradable	biodegradable	ADJ
can-1681	209	16	waterproof	waterproof	ADJ
can-1681	209	17	films	film	NOUN
can-1681	209	18	there	there	PRON
can-1681	209	19	are	be	VERB
can-1681	209	20	nanopores	nanopore	NOUN
can-1681	209	21	with	with	ADP
can-1681	209	22	the	the	DET
can-1681	209	23	same	same	ADJ
can-1681	209	24	diameter	diameter	NOUN
can-1681	209	25	as	as	ADP
can-1681	209	26	the	the	DET
can-1681	209	27	active	active	ADJ
can-1681	209	28	material	material	NOUN
can-1681	209	29	on	on	ADP
can-1681	209	30	one	one	NUM
can-1681	209	31	side	side	NOUN
can-1681	209	32	,	,	PUNCT
can-1681	209	33	and	and	CCONJ
can-1681	209	34	only	only	ADV
can-1681	209	35	one	one	NUM
can-1681	209	36	drug	drug	NOUN
can-1681	209	37	molecule	molecule	NOUN
can-1681	209	38	is	be	AUX
can-1681	209	39	allowed	allow	VERB
can-1681	209	40	to	to	PART
can-1681	209	41	flow	flow	VERB
can-1681	209	42	out	out	ADP
can-1681	209	43	of	of	ADP
can-1681	209	44	the	the	DET
can-1681	209	45	reservoir	reservoir	NOUN
can-1681	209	46	of	of	ADP
can-1681	209	47	each	each	DET
can-1681	209	48	pore	pore	ADJ
can-1681	209	49	at	at	ADP
can-1681	209	50	a	a	DET
can-1681	209	51	time	time	NOUN
can-1681	209	52	.	.	PUNCT
can-1681	210	1	when	when	SCONJ
can-1681	210	2	injecting	inject	VERB
can-1681	210	3	the	the	DET
can-1681	210	4	device	device	NOUN
can-1681	210	5	into	into	ADP
can-1681	210	6	the	the	DET
can-1681	210	7	vitreous	vitreous	ADJ
can-1681	210	8	body	body	NOUN
can-1681	210	9	,	,	PUNCT
can-1681	210	10	it	it	PRON
can-1681	210	11	is	be	AUX
can-1681	210	12	very	very	ADV
can-1681	210	13	thin	thin	ADJ
can-1681	210	14	,	,	PUNCT
can-1681	210	15	only	only	ADV
can-1681	210	16	40	40	NUM
can-1681	210	17	μ	μ	NUM
can-1681	210	18	m	m	NOUN
can-1681	210	19	in	in	ADP
can-1681	210	20	diameter	diameter	NOUN
can-1681	210	21	,	,	PUNCT
can-1681	210	22	and	and	CCONJ
can-1681	210	23	the	the	DET
can-1681	210	24	drug	drug	NOUN
can-1681	210	25	release	release	NOUN
can-1681	210	26	order	order	NOUN
can-1681	210	27	is	be	AUX
can-1681	210	28	close	close	ADJ
can-1681	210	29	to	to	ADP
can-1681	210	30	0	0	NUM
can-1681	210	31	.	.	PUNCT
can-1681	211	1	when	when	SCONJ
can-1681	211	2	most	most	ADJ
can-1681	211	3	drugs	drug	NOUN
can-1681	211	4	are	be	AUX
can-1681	211	5	released	release	VERB
can-1681	211	6	,	,	PUNCT
can-1681	211	7	the	the	DET
can-1681	211	8	polymer	polymer	NOUN
can-1681	211	9	layer	layer	NOUN
can-1681	211	10	then	then	ADV
can-1681	211	11	degrades	degrade	VERB
can-1681	211	12	,	,	PUNCT
can-1681	211	13	eliminating	eliminate	VERB
can-1681	211	14	the	the	DET
can-1681	211	15	need	need	NOUN
can-1681	211	16	to	to	PART
can-1681	211	17	remove	remove	VERB
can-1681	211	18	the	the	DET
can-1681	211	19	device	device	NOUN
can-1681	211	20	.	.	PUNCT
can-1681	212	1	this	this	DET
can-1681	212	2	implant	implant	NOUN
can-1681	212	3	controls	control	VERB
can-1681	212	4	the	the	DET
can-1681	212	5	release	release	NOUN
can-1681	212	6	rate	rate	NOUN
can-1681	212	7	by	by	ADP
can-1681	212	8	adjusting	adjust	VERB
can-1681	212	9	the	the	DET
can-1681	212	10	size	size	NOUN
can-1681	212	11	of	of	ADP
can-1681	212	12	the	the	DET
can-1681	212	13	hole	hole	NOUN
can-1681	212	14	and	and	CCONJ
can-1681	212	15	has	have	AUX
can-1681	212	16	been	be	AUX
can-1681	212	17	shown	show	VERB
can-1681	212	18	to	to	PART
can-1681	212	19	last	last	VERB
can-1681	212	20	for	for	ADP
can-1681	212	21	4	4	NUM
can-1681	212	22	months	month	NOUN
can-1681	212	23	.	.	PUNCT
can-1681	213	1	therefore	therefore	ADV
can-1681	213	2	,	,	PUNCT
can-1681	213	3	it	it	PRON
can-1681	213	4	may	may	AUX
can-1681	213	5	become	become	VERB
can-1681	213	6	the	the	DET
can-1681	213	7	best	good	ADJ
can-1681	213	8	biodegradable	biodegradable	ADJ
can-1681	213	9	implant	implant	NOUN
can-1681	213	10	for	for	ADP
can-1681	213	11	the	the	DET
can-1681	213	12	treatment	treatment	NOUN
can-1681	213	13	of	of	ADP
can-1681	213	14	chronic	chronic	ADJ
can-1681	213	15	retinal	retinal	ADJ
can-1681	213	16	diseases[93	diseases[93	NOUN
can-1681	213	17	]	]	PUNCT
can-1681	213	18	.	.	PUNCT
can-1681	214	1	a	a	DET
can-1681	214	2	similar	similar	ADJ
can-1681	214	3	situation	situation	NOUN
can-1681	214	4	occurred	occur	VERB
can-1681	214	5	when	when	SCONJ
can-1681	214	6	sirolimus	sirolimus	NOUN
can-1681	214	7	was	be	AUX
can-1681	214	8	released	release	VERB
can-1681	214	9	to	to	ADP
can-1681	214	10	the	the	DET
can-1681	214	11	posterior	posterior	ADJ
can-1681	214	12	pole[94	pole[94	NOUN
can-1681	214	13	]	]	PUNCT
can-1681	214	14	through	through	ADP
can-1681	214	15	the	the	DET
can-1681	214	16	same	same	ADJ
can-1681	214	17	device	device	NOUN
can-1681	214	18	.	.	PUNCT
can-1681	215	1	3.14	3.14	NUM
can-1681	215	2	clinical	clinical	ADJ
can-1681	215	3	application	application	NOUN
can-1681	215	4	in	in	ADP
can-1681	215	5	order	order	NOUN
can-1681	215	6	to	to	PART
can-1681	215	7	clearly	clearly	ADV
can-1681	215	8	understand	understand	VERB
can-1681	215	9	the	the	DET
can-1681	215	10	anatomy	anatomy	NOUN
can-1681	215	11	,	,	PUNCT
can-1681	215	12	histology	histology	NOUN
can-1681	215	13	,	,	PUNCT
can-1681	215	14	and	and	CCONJ
can-1681	215	15	physiology	physiology	NOUN
can-1681	215	16	of	of	ADP
can-1681	215	17	different	different	ADJ
can-1681	215	18	eye	eye	NOUN
can-1681	215	19	barriers	barrier	NOUN
can-1681	215	20	,	,	PUNCT
can-1681	215	21	as	as	ADV
can-1681	215	22	well	well	ADV
can-1681	215	23	as	as	ADP
can-1681	215	24	the	the	DET
can-1681	215	25	main	main	ADJ
can-1681	215	26	nanoparticles	nanoparticle	NOUN
can-1681	215	27	developed	develop	VERB
can-1681	215	28	in	in	ADP
can-1681	215	29	the	the	DET
can-1681	215	30	research	research	NOUN
can-1681	215	31	field	field	NOUN
can-1681	215	32	,	,	PUNCT
can-1681	215	33	table	table	NOUN
can-1681	215	34	2	2	NUM
can-1681	215	35	lists	list	VERB
can-1681	215	36	the	the	DET
can-1681	215	37	most	most	ADV
can-1681	215	38	common	common	ADJ
can-1681	215	39	eye	eye	NOUN
can-1681	215	40	diseases	disease	NOUN
can-1681	215	41	treated	treat	VERB
can-1681	215	42	with	with	ADP
can-1681	215	43	nanotechnology	nanotechnology	NOUN
can-1681	215	44	at	at	ADP
can-1681	215	45	different	different	ADJ
can-1681	215	46	action	action	NOUN
can-1681	215	47	sites	site	NOUN
can-1681	215	48	of	of	ADP
can-1681	215	49	eye	eye	NOUN
can-1681	215	50	tissue	tissue	NOUN
can-1681	215	51	and	and	CCONJ
can-1681	215	52	the	the	DET
can-1681	215	53	most	most	ADV
can-1681	215	54	influential	influential	ADJ
can-1681	215	55	eye	eye	NOUN
can-1681	215	56	diseases	disease	NOUN
can-1681	215	57	on	on	ADP
can-1681	215	58	vision	vision	NOUN
can-1681	215	59	.	.	PUNCT
can-1681	216	1	4	4	X
can-1681	216	2	.	.	X
can-1681	216	3	expectation	expectation	NOUN
can-1681	216	4	nanotechnology	nanotechnology	NOUN
can-1681	216	5	and	and	CCONJ
can-1681	216	6	nanomedicine	nanomedicine	NOUN
can-1681	216	7	are	be	AUX
can-1681	216	8	widely	widely	ADV
can-1681	216	9	used	use	VERB
can-1681	216	10	in	in	ADP
can-1681	216	11	the	the	DET
can-1681	216	12	field	field	NOUN
can-1681	216	13	of	of	ADP
can-1681	216	14	ophthalmology	ophthalmology	NOUN
can-1681	216	15	.	.	PUNCT
can-1681	217	1	in	in	ADP
can-1681	217	2	many	many	ADJ
can-1681	217	3	ways	way	NOUN
can-1681	217	4	,	,	PUNCT
can-1681	217	5	the	the	DET
can-1681	217	6	use	use	NOUN
can-1681	217	7	of	of	ADP
can-1681	217	8	these	these	DET
can-1681	217	9	devices	device	NOUN
can-1681	217	10	and	and	CCONJ
can-1681	217	11	nano	nano	NOUN
can-1681	217	12	agents	agent	NOUN
can-1681	217	13	contributes	contribute	VERB
can-1681	217	14	to	to	ADP
can-1681	217	15	the	the	DET
can-1681	217	16	bioavailability	bioavailability	NOUN
can-1681	217	17	of	of	ADP
can-1681	217	18	drugs	drug	NOUN
can-1681	217	19	,	,	PUNCT
can-1681	217	20	allows	allow	VERB
can-1681	217	21	diffusion	diffusion	NOUN
can-1681	217	22	through	through	ADP
can-1681	217	23	anatomical	anatomical	ADJ
can-1681	217	24	barriers	barrier	NOUN
can-1681	217	25	which	which	PRON
can-1681	217	26	may	may	AUX
can-1681	217	27	reduce	reduce	VERB
can-1681	217	28	the	the	DET
can-1681	217	29	side	side	NOUN
can-1681	217	30	effects	effect	NOUN
can-1681	217	31	of	of	ADP
can-1681	217	32	the	the	DET
can-1681	217	33	traditional	traditional	ADJ
can-1681	217	34	use	use	NOUN
can-1681	217	35	of	of	ADP
can-1681	217	36	topical	topical	ADJ
can-1681	217	37	ophthalmic	ophthalmic	ADJ
can-1681	217	38	drugs	drug	NOUN
can-1681	217	39	,	,	PUNCT
can-1681	217	40	and	and	CCONJ
can-1681	217	41	is	be	AUX
can-1681	217	42	likely	likely	ADJ
can-1681	217	43	to	to	PART
can-1681	217	44	reduce	reduce	VERB
can-1681	217	45	invasive	invasive	ADJ
can-1681	217	46	intervention	intervention	NOUN
can-1681	217	47	to	to	ADP
can-1681	217	48	the	the	DET
can-1681	217	49	posterior	posterior	ADJ
can-1681	217	50	pole	pole	NOUN
can-1681	217	51	to	to	ADP
can-1681	217	52	some	some	DET
can-1681	217	53	extent	extent	NOUN
can-1681	217	54	as	as	ADV
can-1681	217	55	well	well	ADV
can-1681	217	56	as	as	ADP
can-1681	217	57	reducing	reduce	VERB
can-1681	217	58	complications	complication	NOUN
can-1681	217	59	after	after	ADP
can-1681	217	60	using	use	VERB
can-1681	217	61	some	some	DET
can-1681	217	62	drugs	drug	NOUN
can-1681	217	63	that	that	PRON
can-1681	217	64	need	need	VERB
can-1681	217	65	surgical	surgical	ADJ
can-1681	217	66	treatment	treatment	NOUN
can-1681	217	67	.	.	PUNCT
can-1681	218	1	finally	finally	ADV
can-1681	218	2	,	,	PUNCT
can-1681	218	3	the	the	DET
can-1681	218	4	benefits	benefit	NOUN
can-1681	218	5	of	of	ADP
can-1681	218	6	drugs	drug	NOUN
can-1681	218	7	have	have	AUX
can-1681	218	8	been	be	AUX
can-1681	218	9	optimized	optimize	VERB
can-1681	218	10	and	and	CCONJ
can-1681	218	11	the	the	DET
can-1681	218	12	negative	negative	ADJ
can-1681	218	13	effects	effect	NOUN
can-1681	218	14	have	have	AUX
can-1681	218	15	been	be	AUX
can-1681	218	16	reduced	reduce	VERB
can-1681	218	17	,	,	PUNCT
can-1681	218	18	opening	open	VERB
can-1681	218	19	a	a	DET
can-1681	218	20	huge	huge	ADJ
can-1681	218	21	window	window	NOUN
can-1681	218	22	within	within	ADP
can-1681	218	23	the	the	DET
can-1681	218	24	scope	scope	NOUN
can-1681	218	25	of	of	ADP
can-1681	218	26	so	so	ADV
can-1681	218	27	-	-	PUNCT
can-1681	218	28	called	call	VERB
can-1681	218	29	personalized	personalized	ADJ
can-1681	218	30	drugs	drug	NOUN
can-1681	218	31	,	,	PUNCT
can-1681	218	32	which	which	PRON
can-1681	218	33	likely	likely	ADV
can-1681	218	34	require	require	VERB
can-1681	218	35	further	further	ADJ
can-1681	218	36	research	research	NOUN
can-1681	218	37	on	on	ADP
can-1681	218	38	people	people	NOUN
can-1681	218	39	with	with	ADP
can-1681	218	40	74	74	NUM
can-1681	218	41	table	table	NOUN
can-1681	218	42	2	2	NUM
can-1681	218	43	.	.	PUNCT
can-1681	218	44	common	common	ADJ
can-1681	218	45	eye	eye	NOUN
can-1681	218	46	diseases	disease	NOUN
can-1681	218	47	and	and	CCONJ
can-1681	218	48	treatment	treatment	NOUN
can-1681	218	49	application	application	NOUN
can-1681	218	50	pathology	pathology	NOUN
can-1681	218	51	drugs	drug	NOUN
can-1681	218	52	/	/	SYM
can-1681	218	53	devices	device	NOUN
can-1681	218	54	therapeutic	therapeutic	ADJ
can-1681	218	55	target	target	NOUN
can-1681	218	56	associated	associate	VERB
can-1681	218	57	nanoparticles	nanoparticle	NOUN
can-1681	218	58	mechanism	mechanism	NOUN
can-1681	218	59	of	of	ADP
can-1681	218	60	np	np	PROPN
can-1681	218	61	action	action	NOUN
can-1681	218	62	keratitis	keratitis	NOUN
can-1681	218	63	ofloxacino	ofloxacino	NOUN
can-1681	218	64	,	,	PUNCT
can-1681	218	65	colirios	colirio	NOUN
can-1681	218	66	,	,	PUNCT
can-1681	218	67	aciclovir[95	aciclovir[95	NOUN
can-1681	218	68	]	]	PUNCT
can-1681	218	69	fluoroquinolone	fluoroquinolone	NOUN
can-1681	218	70	.	.	PUNCT
can-1681	219	1	inhibition	inhibition	NOUN
can-1681	219	2	of	of	ADP
can-1681	219	3	topoisomerase	topoisomerase	ADJ
can-1681	219	4	ii	ii	PROPN
can-1681	219	5	and	and	CCONJ
can-1681	219	6	iv	iv	PROPN
can-1681	219	7	.	.	PUNCT
can-1681	219	8	herpes	herpe	NOUN
can-1681	219	9	polymerase	polymerase	NOUN
can-1681	219	10	dna	dna	NOUN
can-1681	219	11	inhibitor	inhibitor	NOUN
can-1681	219	12	polyethylene	polyethylene	NOUN
can-1681	219	13	glycol	glycol	NOUN
can-1681	219	14	oxide	oxide	NOUN
can-1681	219	15	and	and	CCONJ
can-1681	219	16	eudragit	eudragit	NOUN
can-1681	219	17	®	®	NOUN
can-1681	219	18	in	in	ADP
can-1681	219	19	the	the	DET
can-1681	219	20	form	form	NOUN
can-1681	219	21	of	of	ADP
can-1681	219	22	microspheres	microsphere	NOUN
can-1681	219	23	acyclovir	acyclovir	PROPN
can-1681	219	24	drug	drug	PROPN
can-1681	219	25	encapsulated	encapsulate	VERB
can-1681	219	26	by	by	ADP
can-1681	219	27	polylactic	polylactic	ADJ
can-1681	219	28	acid	acid	NOUN
can-1681	219	29	microspheres	microsphere	NOUN
can-1681	219	30	improve	improve	VERB
can-1681	219	31	the	the	DET
can-1681	219	32	bioavailability	bioavailability	NOUN
can-1681	219	33	and	and	CCONJ
can-1681	219	34	controlled	control	VERB
can-1681	219	35	release	release	NOUN
can-1681	219	36	of	of	ADP
can-1681	219	37	antibiotics	antibiotic	NOUN
can-1681	219	38	.	.	PUNCT
can-1681	220	1	delay	delay	VERB
can-1681	220	2	the	the	DET
can-1681	220	3	degradation	degradation	NOUN
can-1681	220	4	of	of	ADP
can-1681	220	5	acyclovir	acyclovir	PROPN
can-1681	220	6	prodrug	prodrug	VERB
can-1681	220	7	conjunctivitis	conjunctivitis	NOUN
can-1681	220	8	tobramicina	tobramicina	PROPN
can-1681	220	9	,	,	PUNCT
can-1681	220	10	colirios[96	colirios[96	NOUN
can-1681	220	11	]	]	PUNCT
can-1681	220	12	inhibit	inhibit	VERB
can-1681	220	13	the	the	DET
can-1681	220	14	synthesis	synthesis	NOUN
can-1681	220	15	and	and	CCONJ
can-1681	220	16	binding	binding	NOUN
can-1681	220	17	of	of	ADP
can-1681	220	18	polypeptides	polypeptide	NOUN
can-1681	220	19	in	in	ADP
can-1681	220	20	ribosomes	ribosome	NOUN
can-1681	220	21	.	.	PUNCT
can-1681	221	1	solid	solid	ADJ
can-1681	221	2	lipid	lipid	NOUN
can-1681	221	3	np	np	INTJ
can-1681	221	4	they	they	PRON
can-1681	221	5	increase	increase	VERB
can-1681	221	6	the	the	DET
can-1681	221	7	bioavailability	bioavailability	NOUN
can-1681	221	8	of	of	ADP
can-1681	221	9	the	the	DET
can-1681	221	10	corneal	corneal	ADJ
can-1681	221	11	surface	surface	NOUN
can-1681	221	12	and	and	CCONJ
can-1681	221	13	help	help	VERB
can-1681	221	14	retain	retain	VERB
can-1681	221	15	it	it	PRON
can-1681	221	16	in	in	ADP
can-1681	221	17	the	the	DET
can-1681	221	18	conjunctival	conjunctival	NOUN
can-1681	221	19	sac	sac	NOUN
can-1681	221	20	dry	dry	ADJ
can-1681	221	21	keratoconjunctivitis	keratoconjunctivitis	PROPN
can-1681	221	22	ciclosporina	ciclosporina	PROPN
can-1681	221	23	a	a	DET
can-1681	221	24	,	,	PUNCT
can-1681	221	25	colirios[97	colirios[97	ADJ
can-1681	221	26	]	]	PUNCT
can-1681	221	27	immune	immune	ADJ
can-1681	221	28	modulators	modulator	NOUN
can-1681	221	29	that	that	PRON
can-1681	221	30	prevent	prevent	VERB
can-1681	221	31	t	t	PROPN
can-1681	221	32	lymphocyte	lymphocyte	ADJ
can-1681	221	33	activation	activation	NOUN
can-1681	221	34	.	.	PUNCT
can-1681	222	1	chitosan	chitosan	NOUN
can-1681	222	2	sustained	sustain	VERB
can-1681	222	3	release	release	NOUN
can-1681	222	4	carrier	carrier	NOUN
can-1681	222	5	uveitis	uveitis	NOUN
can-1681	222	6	nano	nano	NOUN
can-1681	222	7	suspension	suspension	NOUN
can-1681	222	8	of	of	ADP
can-1681	222	9	prednisone[52	prednisone[52	NOUN
can-1681	222	10	]	]	PUNCT
can-1681	222	11	subconjunctival	subconjunctival	PROPN
can-1681	222	12	prednisolone	prednisolone	PROPN
can-1681	222	13	injection[52	injection[52	PROPN
can-1681	222	14	]	]	X
can-1681	222	15	intravitreal	intravitreal	ADJ
can-1681	222	16	injection	injection	NOUN
can-1681	222	17	of	of	ADP
can-1681	222	18	infliximab[53	infliximab[53	NOUN
can-1681	222	19	]	]	X
can-1681	222	20	prostaglandin	prostaglandin	NOUN
can-1681	222	21	and	and	CCONJ
can-1681	222	22	leukopenia	leukopenia	ADJ
can-1681	222	23	monoclonal	monoclonal	NOUN
can-1681	222	24	antibody	antibody	NOUN
can-1681	222	25	synthesis	synthesis	NOUN
can-1681	222	26	inhibitors	inhibitor	NOUN
can-1681	222	27	that	that	PRON
can-1681	222	28	inhibit	inhibit	VERB
can-1681	222	29	tnf	tnf	PROPN
can-1681	222	30	-	-	PUNCT
can-1681	222	31	α	α	NOUN
can-1681	222	32	activity	activity	NOUN
can-1681	222	33	.	.	PUNCT
can-1681	223	1	submicron	submicron	NOUN
can-1681	223	2	colloidal	colloidal	NOUN
can-1681	223	3	carrier	carrier	NOUN
can-1681	223	4	of	of	ADP
can-1681	223	5	hydrophobic	hydrophobic	NOUN
can-1681	223	6	drugs	drug	NOUN
can-1681	223	7	in	in	ADP
can-1681	223	8	surfactant	surfactant	NOUN
can-1681	223	9	stabilized	stabilize	VERB
can-1681	223	10	medium	medium	ADJ
can-1681	223	11	sustained	sustain	VERB
can-1681	223	12	release	release	NOUN
can-1681	223	13	and	and	CCONJ
can-1681	223	14	controlled	control	VERB
can-1681	223	15	release	release	NOUN
can-1681	223	16	of	of	ADP
can-1681	223	17	drugs	drug	NOUN
can-1681	223	18	,	,	PUNCT
can-1681	223	19	as	as	ADV
can-1681	223	20	well	well	ADV
can-1681	223	21	as	as	ADP
can-1681	223	22	higher	high	ADJ
can-1681	223	23	bioavailability	bioavailability	NOUN
can-1681	223	24	and	and	CCONJ
can-1681	223	25	lower	low	ADJ
can-1681	223	26	toxicity	toxicity	NOUN
can-1681	223	27	cataract	cataract	NOUN
can-1681	223	28	lithium	lithium	NOUN
can-1681	223	29	with	with	ADP
can-1681	223	30	metabolic	metabolic	NOUN
can-1681	223	31	activity[98	activity[98	NOUN
can-1681	223	32	]	]	PUNCT
can-1681	223	33	inhibit	inhibit	NOUN
can-1681	223	34	ros	ros	NOUN
can-1681	223	35	activity	activity	NOUN
can-1681	223	36	and	and	CCONJ
can-1681	223	37	regulate	regulate	VERB
can-1681	223	38	the	the	DET
can-1681	223	39	level	level	NOUN
can-1681	223	40	of	of	ADP
can-1681	223	41	h2o2	h2o2	NOUN
can-1681	223	42	and	and	CCONJ
can-1681	223	43	lipid	lipid	NOUN
can-1681	223	44	peroxidation	peroxidation	NOUN
can-1681	223	45	in	in	ADP
can-1681	223	46	the	the	DET
can-1681	223	47	surrounding	surround	VERB
can-1681	223	48	environment	environment	NOUN
can-1681	223	49	.	.	PUNCT
can-1681	224	1	deposition	deposition	NOUN
can-1681	224	2	of	of	ADP
can-1681	224	3	platinum	platinum	NOUN
can-1681	224	4	nanoparticles	nanoparticle	NOUN
can-1681	224	5	by	by	ADP
can-1681	224	6	magnetron	magnetron	NOUN
can-1681	224	7	sputtering	sputtering	ADJ
can-1681	224	8	inorganic	inorganic	ADJ
can-1681	224	9	catalytic	catalytic	ADJ
can-1681	224	10	antioxidant	antioxidant	ADJ
can-1681	224	11	glaucoma	glaucoma	NOUN
can-1681	224	12	nano	nano	NOUN
can-1681	224	13	transporters	transporter	NOUN
can-1681	224	14	:	:	PUNCT
can-1681	224	15	pilocarpine	pilocarpine	NOUN
can-1681	224	16	,	,	PUNCT
can-1681	224	17	timolol	timolol	NOUN
can-1681	224	18	,	,	PUNCT
can-1681	224	19	carbonic	carbonic	ADJ
can-1681	224	20	anhydrase	anhydrase	NOUN
can-1681	224	21	inhibitor	inhibitor	NOUN
can-1681	224	22	,	,	PUNCT
can-1681	224	23	acetazolamida	acetazolamida	PROPN
can-1681	224	24	,	,	PUNCT
can-1681	224	25	dorzolamida	dorzolamida	PROPN
can-1681	224	26	,	,	PUNCT
can-1681	224	27	brinazolamida	brinazolamida	NOUN
can-1681	224	28	and	and	CCONJ
can-1681	224	29	brimonidina[99	brimonidina[99	ADJ
can-1681	224	30	]	]	X
can-1681	224	31	silicone	silicone	NOUN
can-1681	224	32	and	and	CCONJ
can-1681	224	33	hydrogel	hydrogel	NOUN
can-1681	224	34	contact	contact	NOUN
can-1681	224	35	lenses	lense	VERB
can-1681	224	36	hydrogel	hydrogel	NOUN
can-1681	224	37	contact	contact	NOUN
can-1681	224	38	lenses	lense	NOUN
can-1681	224	39	containing	contain	VERB
can-1681	224	40	thymolol[74	thymolol[74	PRON
can-1681	224	41	]	]	X
can-1681	224	42	thymolol	thymolol	NOUN
can-1681	224	43	-	-	PUNCT
can-1681	224	44	containing	contain	VERB
can-1681	224	45	contact	contact	NOUN
can-1681	224	46	lenses[91	lenses[91	PROPN
can-1681	224	47	]	]	PUNCT
can-1681	224	48	wireless	wireless	ADJ
can-1681	224	49	sensors[95	sensors[95	NOUN
can-1681	224	50	]	]	X
can-1681	224	51	traditional	traditional	ADJ
can-1681	224	52	treatment	treatment	NOUN
can-1681	224	53	of	of	ADP
can-1681	224	54	non	non	ADJ
can-1681	224	55	-	-	ADJ
can-1681	224	56	selective	selective	ADJ
can-1681	224	57	β	β	NOUN
can-1681	224	58	-	-	NOUN
can-1681	224	59	blockers	blocker	NOUN
can-1681	224	60	to	to	PART
can-1681	224	61	reduce	reduce	VERB
can-1681	224	62	aqueous	aqueous	ADJ
can-1681	224	63	humor	humor	NOUN
can-1681	224	64	.	.	PUNCT
can-1681	225	1	continuous	continuous	ADJ
can-1681	225	2	intraocular	intraocular	ADJ
can-1681	225	3	pressure	pressure	NOUN
can-1681	225	4	monitoring	monitoring	NOUN
can-1681	225	5	.	.	PUNCT
can-1681	226	1	dendrimers	dendrimer	NOUN
can-1681	226	2	,	,	PUNCT
can-1681	226	3	liposomes	liposome	NOUN
can-1681	226	4	,	,	PUNCT
can-1681	226	5	nanocapsules	nanocapsule	NOUN
can-1681	226	6	,	,	PUNCT
can-1681	226	7	nanospheres	nanosphere	NOUN
can-1681	226	8	,	,	PUNCT
can-1681	226	9	hydrogels	hydrogel	NOUN
can-1681	226	10	pgt	pgt	PROPN
can-1681	226	11	(	(	PUNCT
can-1681	226	12	triglyceride	triglyceride	ADJ
can-1681	226	13	)	)	PUNCT
can-1681	226	14	np	np	PRON
can-1681	226	15	gold	gold	NOUN
can-1681	226	16	drug	drug	NOUN
can-1681	226	17	sustained	sustain	VERB
can-1681	226	18	release	release	NOUN
can-1681	226	19	increases	increase	VERB
can-1681	226	20	the	the	DET
can-1681	226	21	loading	loading	NOUN
can-1681	226	22	and	and	CCONJ
can-1681	226	23	absorption	absorption	NOUN
can-1681	226	24	of	of	ADP
can-1681	226	25	the	the	DET
can-1681	226	26	thymus	thymus	ADJ
can-1681	226	27	wet	wet	ADJ
can-1681	226	28	dmre	dmre	NOUN
can-1681	226	29	hyaluronic	hyaluronic	ADJ
can-1681	226	30	acid	acid	NOUN
can-1681	226	31	implant	implant	NOUN
can-1681	226	32	:	:	PUNCT
can-1681	226	33	bevacizumab[100	bevacizumab[100	PROPN
can-1681	226	34	]	]	X
can-1681	226	35	nanopore	nanopore	ADJ
can-1681	226	36	devices	device	NOUN
can-1681	226	37	:	:	PUNCT
can-1681	226	38	ranibizumab	ranibizumab	NOUN
can-1681	226	39	biodegradable[92	biodegradable[92	PROPN
can-1681	226	40	]	]	PUNCT
can-1681	226	41	humanized	humanize	VERB
can-1681	226	42	monoclonal	monoclonal	NOUN
can-1681	226	43	antibody	antibody	NOUN
can-1681	226	44	against	against	ADP
can-1681	226	45	vascular	vascular	ADJ
can-1681	226	46	endothelial	endothelial	ADJ
can-1681	226	47	growth	growth	NOUN
can-1681	226	48	factor	factor	NOUN
can-1681	226	49	.	.	PUNCT
can-1681	227	1	chitosan	chitosan	NOUN
can-1681	227	2	na	na	ADP
can-1681	227	3	sustained	sustain	VERB
can-1681	227	4	release	release	NOUN
can-1681	227	5	vehicle	vehicle	NOUN
can-1681	227	6	drug	drug	NOUN
can-1681	227	7	release	release	NOUN
can-1681	227	8	through	through	ADP
can-1681	227	9	nanopores	nanopore	NOUN
can-1681	227	10	diabetic	diabetic	ADJ
can-1681	227	11	retinopathy	retinopathy	ADJ
can-1681	227	12	reservoir	reservoir	NOUN
can-1681	227	13	stimulation	stimulation	NOUN
can-1681	227	14	response	response	NOUN
can-1681	227	15	device	device	NOUN
can-1681	227	16	:	:	PUNCT
can-1681	227	17	nintedanib[101	nintedanib[101	PROPN
can-1681	227	18	]	]	PUNCT
can-1681	227	19	vascular	vascular	ADJ
can-1681	227	20	kinase	kinase	NOUN
can-1681	227	21	inhibitor	inhibitor	NOUN
can-1681	227	22	,	,	PUNCT
can-1681	227	23	blocking	block	VERB
can-1681	227	24	vegf	vegf	NOUN
can-1681	227	25	receptor	receptor	NOUN
can-1681	227	26	,	,	PUNCT
can-1681	227	27	platelet	platelet	NOUN
can-1681	227	28	-	-	PUNCT
can-1681	227	29	derived	derive	VERB
can-1681	227	30	growth	growth	NOUN
can-1681	227	31	factor	factor	NOUN
can-1681	227	32	receptor	receptor	NOUN
can-1681	227	33	,	,	PUNCT
can-1681	227	34	fibroblast	fibroblast	ADJ
can-1681	227	35	growth	growth	NOUN
can-1681	227	36	factor	factor	NOUN
can-1681	227	37	receptor	receptor	NOUN
can-1681	227	38	polylactic	polylactic	ADJ
can-1681	227	39	acid	acid	NOUN
can-1681	227	40	glycolic	glycolic	NOUN
can-1681	227	41	acid	acid	NOUN
can-1681	227	42	microspheres	microsphere	NOUN
can-1681	227	43	and	and	CCONJ
can-1681	227	44	nitrobenzene	nitrobenzene	PROPN
can-1681	227	45	monomer	monomer	PROPN
can-1681	227	46	uv	uv	PROPN
can-1681	227	47	stimulates	stimulate	VERB
can-1681	227	48	drug	drug	NOUN
can-1681	227	49	release	release	NOUN
can-1681	227	50	retinitis	retinitis	NOUN
can-1681	227	51	pigmentosa	pigmentosa	VERB
can-1681	227	52	vitreous	vitreous	ADJ
can-1681	227	53	fluorooctane	fluorooctane	ADJ
can-1681	227	54	sulfonate	sulfonate	ADJ
can-1681	227	55	microglia	microglia	ADJ
can-1681	227	56	activity	activity	NOUN
can-1681	227	57	attenuation	attenuation	NOUN
can-1681	227	58	.	.	PUNCT
can-1681	228	1	polyamide	polyamide	NOUN
can-1681	228	2	dendritic	dendritic	ADJ
can-1681	228	3	molecule	molecule	NOUN
can-1681	228	4	drug	drug	NOUN
can-1681	228	5	sustained	sustain	VERB
can-1681	228	6	release	release	NOUN
can-1681	228	7	retinoblastoma	retinoblastoma	NOUN
can-1681	228	8	subconjunctival	subconjunctival	NOUN
can-1681	228	9	carboplatin[60	carboplatin[60	X
can-1681	228	10	]	]	PUNCT
can-1681	228	11	photodynamic	photodynamic	ADJ
can-1681	228	12	therapy	therapy	NOUN
can-1681	228	13	and	and	CCONJ
can-1681	228	14	vertepofina[102	vertepofina[102	PROPN
can-1681	228	15	]	]	PUNCT
can-1681	228	16	alkylating	alkylate	VERB
can-1681	228	17	agent	agent	NOUN
can-1681	228	18	,	,	PUNCT
can-1681	228	19	inhibiting	inhibit	VERB
can-1681	228	20	dna	dna	NOUN
can-1681	228	21	replication	replication	NOUN
can-1681	228	22	,	,	PUNCT
can-1681	228	23	rna	rna	NOUN
can-1681	228	24	transcription	transcription	NOUN
can-1681	228	25	,	,	PUNCT
can-1681	228	26	dano	dano	PROPN
can-1681	228	27	protein	protein	NOUN
can-1681	228	28	synthesis	synthesis	NOUN
can-1681	228	29	,	,	PUNCT
can-1681	228	30	selective	selective	ADJ
can-1681	228	31	neovascular	neovascular	ADJ
can-1681	228	32	endothelial	endothelial	ADJ
can-1681	228	33	cells	cell	NOUN
can-1681	228	34	,	,	PUNCT
can-1681	228	35	inducing	induce	VERB
can-1681	228	36	apoptosis	apoptosis	NOUN
can-1681	228	37	and	and	CCONJ
can-1681	228	38	autophagy	autophagy	NOUN
can-1681	228	39	.	.	PUNCT
can-1681	229	1	np	np	AUX
can-1681	229	2	dendritic	dendritic	ADJ
can-1681	229	3	polyamidoamine	polyamidoamine	PROPN
can-1681	229	4	non	non	ADJ
can-1681	229	5	-	-	ADJ
can-1681	229	6	thermal	thermal	ADJ
can-1681	229	7	laser	laser	NOUN
can-1681	229	8	activated	activate	VERB
can-1681	229	9	liposome	liposome	VERB
can-1681	229	10	vertebral	vertebral	ADJ
can-1681	229	11	body	body	NOUN
can-1681	229	12	.	.	PUNCT
can-1681	230	1	sustained	sustain	VERB
can-1681	230	2	release	release	NOUN
can-1681	230	3	and	and	CCONJ
can-1681	230	4	controlled	control	VERB
can-1681	230	5	release	release	NOUN
can-1681	230	6	of	of	ADP
can-1681	230	7	drugs	drug	NOUN
can-1681	230	8	reactive	reactive	ADJ
can-1681	230	9	oxygen	oxygen	NOUN
can-1681	230	10	species	species	NOUN
can-1681	230	11	production	production	NOUN
can-1681	230	12	and	and	CCONJ
can-1681	230	13	cell	cell	NOUN
can-1681	230	14	death	death	NOUN
can-1681	230	15	in	in	ADP
can-1681	230	16	tumor	tumor	NOUN
can-1681	230	17	cells	cell	NOUN
can-1681	230	18	.	.	PUNCT
can-1681	231	1	75	75	NUM
can-1681	231	2	table	table	NOUN
can-1681	231	3	2	2	NUM
can-1681	231	4	.	.	PUNCT
can-1681	231	5	(	(	PUNCT
can-1681	231	6	continued	continue	VERB
can-1681	231	7	)	)	PUNCT
can-1681	231	8	pathology	pathology	NOUN
can-1681	231	9	drugs	drug	NOUN
can-1681	231	10	/	/	SYM
can-1681	231	11	devices	device	NOUN
can-1681	231	12	therapeutic	therapeutic	ADJ
can-1681	231	13	target	target	NOUN
can-1681	231	14	associated	associate	VERB
can-1681	231	15	nanoparticles	nanoparticle	NOUN
can-1681	231	16	mechanism	mechanism	NOUN
can-1681	231	17	of	of	ADP
can-1681	231	18	np	np	PRON
can-1681	231	19	action	action	NOUN
can-1681	231	20	optic	optic	ADJ
can-1681	231	21	neuromyelitis	neuromyelitis	PROPN
can-1681	231	22	biosensor[104	biosensor[104	PROPN
can-1681	231	23	]	]	PUNCT
can-1681	231	24	na	na	PART
can-1681	231	25	carbon	carbon	NOUN
can-1681	231	26	nano	nano	NOUN
can-1681	231	27	-	-	PUNCT
can-1681	231	28	tubes	tube	NOUN
can-1681	231	29	aqp4	aqp4	PROPN
can-1681	231	30	antibody	antibody	NOUN
can-1681	231	31	detection	detection	NOUN
can-1681	231	32	.	.	PUNCT
can-1681	232	1	endophthalmitis	endophthalmitis	ADJ
can-1681	232	2	damycin	damycin	ADJ
can-1681	232	3	,	,	PUNCT
can-1681	232	4	cholinesterase[105	cholinesterase[105	NOUN
can-1681	232	5	]	]	PUNCT
can-1681	232	6	anti	anti	ADJ
can-1681	232	7	-	-	ADJ
can-1681	232	8	gram	gram	ADJ
can-1681	232	9	positive	positive	ADJ
can-1681	232	10	natural	natural	ADJ
can-1681	232	11	lipopeptide	lipopeptide	NOUN
can-1681	232	12	antibiotics	antibiotic	NOUN
can-1681	232	13	,	,	PUNCT
can-1681	232	14	including	include	VERB
can-1681	232	15	samr	samr	PROPN
can-1681	232	16	.	.	PUNCT
can-1681	233	1	chitosan	chitosan	PROPN
can-1681	233	2	promote	promote	VERB
can-1681	233	3	the	the	DET
can-1681	233	4	penetration	penetration	NOUN
can-1681	233	5	of	of	ADP
can-1681	233	6	antibiotics	antibiotic	NOUN
can-1681	233	7	by	by	ADP
can-1681	233	8	opening	open	VERB
can-1681	233	9	the	the	DET
can-1681	233	10	connection	connection	NOUN
can-1681	233	11	between	between	ADP
can-1681	233	12	corneal	corneal	ADJ
can-1681	233	13	cells	cell	NOUN
can-1681	233	14	.	.	PUNCT
can-1681	234	1	aqp4	aqp4	PROPN
can-1681	234	2	:	:	PUNCT
can-1681	234	3	antithrombin	antithrombin	PROPN
can-1681	234	4	4	4	NUM
can-1681	234	5	;	;	PUNCT
can-1681	234	6	dmre	dmre	NOUN
can-1681	234	7	:	:	PUNCT
can-1681	234	8	age	age	NOUN
can-1681	234	9	-	-	PUNCT
can-1681	234	10	related	relate	VERB
can-1681	234	11	macular	macular	ADJ
can-1681	234	12	degeneration	degeneration	NOUN
can-1681	234	13	;	;	PUNCT
can-1681	234	14	erk	erk	NOUN
can-1681	234	15	:	:	PUNCT
can-1681	234	16	extracellular	extracellular	ADJ
can-1681	234	17	signal	signal	NOUN
can-1681	234	18	-	-	PUNCT
can-1681	234	19	regulated	regulate	VERB
can-1681	234	20	kinase	kinase	NOUN
can-1681	234	21	;	;	PUNCT
can-1681	234	22	lio	lio	X
can-1681	234	23	:	:	PUNCT
can-1681	234	24	intraocular	intraocular	ADJ
can-1681	234	25	lens	len	NOUN
can-1681	234	26	;	;	PUNCT
can-1681	235	1	na	na	NOUN
can-1681	235	2	:	:	PUNCT
can-1681	235	3	not	not	PART
can-1681	235	4	applicable	applicable	ADJ
can-1681	235	5	;	;	PUNCT
can-1681	235	6	np	np	X
can-1681	235	7	:	:	PUNCT
can-1681	235	8	nanoparticles	nanoparticle	NOUN
can-1681	235	9	;	;	PUNCT
can-1681	235	10	pio	pio	ADJ
can-1681	235	11	:	:	PUNCT
can-1681	235	12	intraocular	intraocular	ADJ
can-1681	235	13	pressure	pressure	NOUN
can-1681	235	14	;	;	PUNCT
can-1681	236	1	ros	ros	PROPN
can-1681	236	2	:	:	PUNCT
can-1681	236	3	reactive	reactive	ADJ
can-1681	236	4	oxygen	oxygen	NOUN
can-1681	236	5	species	specie	NOUN
can-1681	236	6	;	;	PUNCT
can-1681	236	7	samr	samr	ADJ
can-1681	236	8	:	:	PUNCT
can-1681	236	9	methicillin	methicillin	NOUN
can-1681	236	10	-	-	PUNCT
can-1681	236	11	resistant	resistant	ADJ
can-1681	236	12	staphylococcus	staphylococcus	NOUN
can-1681	236	13	aureus	aureus	NOUN
can-1681	236	14	;	;	PUNCT
can-1681	236	15	vegfr-2	vegfr-2	NUM
can-1681	236	16	:	:	PUNCT
can-1681	236	17	vascular	vascular	ADJ
can-1681	236	18	endothelial	endothelial	ADJ
can-1681	236	19	growth	growth	NOUN
can-1681	236	20	factor	factor	NOUN
can-1681	236	21	receptor	receptor	NOUN
can-1681	236	22	2	2	NUM
can-1681	236	23	.	.	PUNCT
can-1681	236	24	individual	individual	ADJ
can-1681	236	25	characteristics	characteristic	NOUN
can-1681	236	26	,	,	PUNCT
can-1681	236	27	including	include	VERB
can-1681	236	28	continuous	continuous	ADJ
can-1681	236	29	research	research	NOUN
can-1681	236	30	on	on	ADP
can-1681	236	31	various	various	ADJ
can-1681	236	32	animal	animal	NOUN
can-1681	236	33	and	and	CCONJ
can-1681	236	34	laboratory	laboratory	NOUN
can-1681	236	35	models	model	NOUN
can-1681	236	36	.	.	PUNCT
can-1681	237	1	conflict	conflict	NOUN
can-1681	237	2	of	of	ADP
can-1681	237	3	interest	interest	NOUN
can-1681	237	4	the	the	DET
can-1681	237	5	authors	author	NOUN
can-1681	237	6	claim	claim	VERB
can-1681	237	7	that	that	SCONJ
can-1681	237	8	there	there	PRON
can-1681	237	9	is	be	VERB
can-1681	237	10	no	no	DET
can-1681	237	11	conflict	conflict	NOUN
can-1681	237	12	of	of	ADP
can-1681	237	13	interest	interest	NOUN
can-1681	237	14	.	.	PUNCT
can-1681	238	1	references	reference	NOUN
can-1681	238	2	1	1	NUM
can-1681	238	3	.	.	PUNCT
can-1681	238	4	salud	salud	PROPN
can-1681	238	5	oomdl	oomdl	NOUN
can-1681	238	6	.	.	PUNCT
can-1681	239	1	blindness	blindness	NOUN
can-1681	239	2	and	and	CCONJ
can-1681	239	3	visual	visual	ADJ
can-1681	239	4	impairment	impairment	NOUN
can-1681	239	5	(	(	PUNCT
can-1681	239	6	in	in	ADP
can-1681	239	7	spanish	spanish	ADJ
can-1681	239	8	)	)	PUNCT
can-1681	239	9	.	.	PUNCT
can-1681	240	1	2019	2019	NUM
can-1681	240	2	.	.	PUNCT
can-1681	241	1	available	available	ADJ
can-1681	241	2	from	from	ADP
can-1681	241	3	:	:	PUNCT
can-1681	241	4	https://www.who.int/es/news-room/fact-sheets/detai	https://www.who.int/es/news-room/fact-sheets/detai	PROPN
can-1681	241	5	l	l	NOUN
can-1681	241	6	/	/	SYM
can-1681	241	7	blindness	blindness	NOUN
can-1681	241	8	-	-	PUNCT
can-1681	241	9	and	and	CCONJ
can-1681	241	10	-	-	PUNCT
can-1681	241	11	vi	vi	NOUN
can-1681	241	12	-	-	PUNCT
can-1681	241	13	airily	airily	ADV
can-1681	241	14	.	.	PUNCT
can-1681	242	1	2	2	X
can-1681	242	2	.	.	X
can-1681	242	3	meng	meng	PROPN
can-1681	242	4	t	t	PROPN
can-1681	242	5	,	,	PUNCT
can-1681	242	6	kurkani	kurkani	PROPN
can-1681	242	7	v	v	NOUN
can-1681	242	8	,	,	PUNCT
can-1681	242	9	simmers	simmer	NOUN
can-1681	242	10	r	r	VERB
can-1681	242	11	,	,	PUNCT
can-1681	242	12	et	et	PROPN
can-1681	242	13	al	al	PROPN
can-1681	242	14	.	.	PUNCT
can-1681	243	1	therapeutic	therapeutic	ADJ
can-1681	243	2	implications	implication	NOUN
can-1681	243	3	of	of	ADP
can-1681	243	4	nanomedicine	nanomedicine	NOUN
can-1681	243	5	for	for	ADP
can-1681	243	6	ocular	ocular	ADJ
can-1681	243	7	drug	drug	NOUN
can-1681	243	8	delivery	delivery	NOUN
can-1681	243	9	.	.	PUNCT
can-1681	244	1	drug	drug	NOUN
can-1681	244	2	discovery	discovery	PROPN
can-1681	244	3	today	today	NOUN
can-1681	244	4	.	.	PUNCT
can-1681	245	1	england	england	PROPN
can-1681	245	2	:	:	PUNCT
can-1681	245	3	elsevier	elsevier	PROPN
can-1681	245	4	co.	co.	PROPN
can-1681	245	5	,	,	PUNCT
can-1681	245	6	ltd	ltd	PROPN
can-1681	245	7	;	;	PUNCT
can-1681	245	8	2019	2019	NUM
can-1681	245	9	.	.	PUNCT
can-1681	246	1	3	3	X
can-1681	246	2	.	.	X
can-1681	246	3	nstc	nstc	NOUN
can-1681	246	4	.	.	PUNCT
can-1681	247	1	national	national	PROPN
can-1681	247	2	nanotechnology	nanotechnology	PROPN
can-1681	247	3	initiative	initiative	NOUN
can-1681	247	4	—	—	PUNCT
can-1681	247	5	leading	lead	VERB
can-1681	247	6	to	to	ADP
can-1681	247	7	the	the	DET
can-1681	247	8	next	next	ADJ
can-1681	247	9	industrial	industrial	ADJ
can-1681	247	10	revolution	revolution	NOUN
can-1681	247	11	.	.	PUNCT
can-1681	248	1	microscale	microscale	ADJ
can-1681	248	2	thermophysical	thermophysical	ADJ
can-1681	248	3	engineering	engineering	NOUN
can-1681	248	4	2000	2000	NUM
can-1681	248	5	;	;	PUNCT
can-1681	248	6	4(3	4(3	NUM
can-1681	248	7	):	):	PUNCT
can-1681	248	8	205–212	205–212	NUM
can-1681	248	9	.	.	PUNCT
can-1681	249	1	4	4	X
can-1681	249	2	.	.	X
can-1681	249	3	guchet	guchet	NOUN
can-1681	249	4	x.	x.	NOUN
can-1681	250	1	what	what	PRON
can-1681	250	2	’s	’	VERB
can-1681	250	3	in	in	ADP
can-1681	250	4	a	a	DET
can-1681	250	5	word	word	NOUN
can-1681	250	6	?	?	PUNCT
can-1681	251	1	the	the	DET
can-1681	251	2	person	person	NOUN
can-1681	251	3	of	of	ADP
can-1681	251	4	personalized	personalized	ADJ
can-1681	251	5	(	(	PUNCT
can-1681	251	6	nano	nano	NOUN
can-1681	251	7	)	)	PUNCT
can-1681	251	8	medicine	medicine	NOUN
can-1681	251	9	.	.	PUNCT
can-1681	252	1	nanomedicine	nanomedicine	NOUN
can-1681	252	2	2015	2015	NUM
can-1681	252	3	;	;	PUNCT
can-1681	252	4	10(20	10(20	NUM
can-1681	252	5	):	):	PUNCT
can-1681	252	6	3167–3179	3167–3179	NOUN
can-1681	252	7	.	.	PUNCT
can-1681	253	1	5	5	X
can-1681	253	2	.	.	PUNCT
can-1681	253	3	feng	feng	PROPN
can-1681	253	4	y	y	PROPN
can-1681	253	5	,	,	PUNCT
can-1681	253	6	zhang	zhang	PROPN
can-1681	253	7	y	y	PROPN
can-1681	253	8	,	,	PUNCT
can-1681	253	9	ying	ying	PROPN
can-1681	253	10	c	c	PROPN
can-1681	253	11	,	,	PUNCT
can-1681	253	12	et	et	PROPN
can-1681	253	13	al	al	PROPN
can-1681	253	14	.	.	PUNCT
can-1681	254	1	corrigendum	corrigendum	PROPN
can-1681	254	2	to	to	ADP
can-1681	254	3	‘	'	PUNCT
can-1681	254	4	nanopore	nanopore	ADV
can-1681	254	5	-	-	PUNCT
can-1681	254	6	based	base	VERB
can-1681	254	7	fourth	fourth	ADJ
can-1681	254	8	-	-	PUNCT
can-1681	254	9	generation	generation	NOUN
can-1681	254	10	dna	dna	NOUN
can-1681	254	11	sequencing	sequence	VERB
can-1681	254	12	technology	technology	NOUN
can-1681	254	13	’	'	PUNCT
can-1681	255	1	[	[	X
can-1681	255	2	gpb	gpb	NOUN
can-1681	255	3	144	144	NUM
can-1681	255	4	(	(	PUNCT
can-1681	255	5	2015)-gpb	2015)-gpb	NUM
can-1681	255	6	13/1	13/1	NUM
can-1681	255	7	(	(	PUNCT
can-1681	255	8	4	4	NUM
can-1681	255	9	-	-	NUM
can-1681	255	10	16	16	NUM
can-1681	255	11	)	)	PUNCT
can-1681	255	12	]	]	PUNCT
can-1681	255	13	.	.	PUNCT
can-1681	256	1	genomic	genomic	ADJ
can-1681	256	2	proteomics	proteomic	NOUN
can-1681	256	3	boinformatics	boinformatic	NOUN
can-1681	256	4	2015	2015	NUM
can-1681	256	5	;	;	PUNCT
can-1681	256	6	13(6	13(6	NUM
can-1681	256	7	):	):	PUNCT
can-1681	256	8	383	383	NUM
can-1681	256	9	.	.	PUNCT
can-1681	257	1	6	6	NUM
can-1681	257	2	.	.	X
can-1681	257	3	peck	peck	PROPN
can-1681	257	4	rw	rw	PROPN
can-1681	257	5	.	.	PROPN
can-1681	257	6	precision	precision	PROPN
can-1681	257	7	medicine	medicine	NOUN
can-1681	257	8	is	be	AUX
can-1681	257	9	not	not	PART
can-1681	257	10	just	just	ADV
can-1681	257	11	genomics	genomic	NOUN
can-1681	257	12	:	:	PUNCT
can-1681	257	13	the	the	DET
can-1681	257	14	right	right	NOUN
can-1681	257	15	dose	dose	NOUN
can-1681	257	16	for	for	ADP
can-1681	257	17	every	every	DET
can-1681	257	18	patient	patient	NOUN
can-1681	257	19	.	.	PUNCT
can-1681	258	1	annual	annual	ADJ
can-1681	258	2	review	review	NOUN
can-1681	258	3	of	of	ADP
can-1681	258	4	pharmacology	pharmacology	NOUN
can-1681	258	5	and	and	CCONJ
can-1681	258	6	toxicology	toxicology	NOUN
can-1681	258	7	2018	2018	NUM
can-1681	258	8	;	;	PUNCT
can-1681	258	9	58	58	NUM
can-1681	258	10	:	:	PUNCT
can-1681	258	11	105–122	105–122	NUM
can-1681	258	12	.	.	NOUN
can-1681	259	1	7	7	X
can-1681	259	2	.	.	PUNCT
can-1681	259	3	ventola	ventola	PROPN
can-1681	259	4	cl	cl	PROPN
can-1681	259	5	.	.	PUNCT
can-1681	260	1	progress	progress	NOUN
can-1681	260	2	in	in	ADP
can-1681	260	3	nanomedicine	nanomedicine	NOUN
can-1681	260	4	:	:	PUNCT
can-1681	260	5	approved	approved	ADJ
can-1681	260	6	and	and	CCONJ
can-1681	260	7	investigational	investigational	ADJ
can-1681	260	8	nanodrugs	nanodrug	NOUN
can-1681	260	9	.	.	PUNCT
can-1681	261	1	p	p	PROPN
can-1681	261	2	&	&	CCONJ
can-1681	261	3	t	t	PROPN
can-1681	261	4	:	:	PUNCT
can-1681	261	5	a	a	DET
can-1681	261	6	peer	peer	NOUN
can-1681	261	7	-	-	PUNCT
can-1681	261	8	reviewed	review	VERB
can-1681	261	9	journal	journal	NOUN
can-1681	261	10	of	of	ADP
can-1681	261	11	formulary	formulary	ADJ
can-1681	261	12	management	management	NOUN
can-1681	261	13	2017	2017	NUM
can-1681	261	14	;	;	PUNCT
can-1681	261	15	42(12	42(12	NUM
can-1681	261	16	):	):	PUNCT
can-1681	261	17	742–755	742–755	NUM
can-1681	261	18	.	.	NOUN
can-1681	261	19	8	8	NUM
can-1681	261	20	.	.	PUNCT
can-1681	261	21	xu	xu	PROPN
can-1681	262	1	q	q	X
can-1681	262	2	,	,	PUNCT
can-1681	262	3	kambanpatti	kambanpatti	PROPN
can-1681	262	4	sp	sp	PROPN
can-1681	262	5	,	,	PUNCT
can-1681	262	6	kannan	kannan	PROPN
can-1681	262	7	rm	rm	PROPN
can-1681	262	8	.	.	PUNCT
can-1681	262	9	nanotechnology	nanotechnology	PROPN
can-1681	262	10	approaches	approach	VERB
can-1681	262	11	for	for	ADP
can-1681	262	12	ocular	ocular	ADJ
can-1681	262	13	drug	drug	NOUN
can-1681	262	14	delivery	delivery	NOUN
can-1681	262	15	.	.	PUNCT
can-1681	263	1	middle	middle	PROPN
can-1681	263	2	east	east	PROPN
can-1681	263	3	african	african	PROPN
can-1681	263	4	journal	journal	NOUN
can-1681	263	5	of	of	ADP
can-1681	263	6	ophthalmology	ophthalmology	NOUN
can-1681	263	7	2013	2013	NUM
can-1681	263	8	;	;	PUNCT
can-1681	263	9	20(1	20(1	NUM
can-1681	263	10	):	):	PUNCT
can-1681	263	11	26–37	26–37	ADJ
can-1681	263	12	.	.	PUNCT
can-1681	264	1	9	9	X
can-1681	264	2	.	.	X
can-1681	264	3	kamaleddin	kamaleddin	PROPN
can-1681	264	4	ma	ma	PROPN
can-1681	264	5	.	.	PUNCT
can-1681	265	1	nano	nano	NOUN
can-1681	265	2	-	-	PUNCT
can-1681	265	3	ophthalmology	ophthalmology	NOUN
can-1681	265	4	:	:	PUNCT
can-1681	265	5	applications	application	NOUN
can-1681	265	6	and	and	CCONJ
can-1681	265	7	considerations	consideration	NOUN
can-1681	265	8	.	.	PUNCT
can-1681	266	1	nanomedicine	nanomedicine	NOUN
can-1681	266	2	:	:	PUNCT
can-1681	266	3	nanotechnology	nanotechnology	NOUN
can-1681	266	4	,	,	PUNCT
can-1681	266	5	biology	biology	NOUN
can-1681	266	6	and	and	CCONJ
can-1681	266	7	medicine	medicine	NOUN
can-1681	266	8	2017	2017	NUM
can-1681	266	9	;	;	PUNCT
can-1681	266	10	13(4	13(4	NUM
can-1681	266	11	):	):	PUNCT
can-1681	266	12	1459–1472	1459–1472	NUM
can-1681	266	13	.	.	PUNCT
can-1681	267	1	10	10	NUM
can-1681	267	2	.	.	PUNCT
can-1681	268	1	zabin	zabin	PROPN
can-1681	268	2	ma	ma	PROPN
can-1681	268	3	,	,	PUNCT
can-1681	268	4	arlow	arlow	PROPN
can-1681	268	5	t	t	PROPN
can-1681	268	6	,	,	PUNCT
can-1681	268	7	ritch	ritch	ADJ
can-1681	268	8	r	r	NOUN
can-1681	268	9	,	,	PUNCT
can-1681	268	10	et	et	PROPN
can-1681	268	11	al	al	PROPN
can-1681	268	12	.	.	PROPN
can-1681	268	13	regenerative	regenerative	ADJ
can-1681	268	14	nanomedicine	nanomedicine	NOUN
can-1681	268	15	for	for	ADP
can-1681	268	16	vision	vision	NOUN
can-1681	268	17	restoration	restoration	NOUN
can-1681	268	18	.	.	PUNCT
can-1681	269	1	mayo	mayo	NOUN
can-1681	269	2	clinic	clinic	PROPN
can-1681	269	3	proceedings	proceeding	NOUN
can-1681	269	4	2013	2013	NUM
can-1681	269	5	;	;	PUNCT
can-1681	269	6	88(12	88(12	NUM
can-1681	269	7	):	):	PUNCT
can-1681	269	8	1480–1490	1480–1490	NUM
can-1681	269	9	.	.	PUNCT
can-1681	270	1	11	11	NUM
can-1681	270	2	.	.	X
can-1681	270	3	dartt	dartt	PROPN
can-1681	270	4	da	da	PROPN
can-1681	270	5	,	,	PUNCT
can-1681	270	6	willcox	willcox	PROPN
can-1681	270	7	md	md	PROPN
can-1681	270	8	.	.	PROPN
can-1681	271	1	complexity	complexity	NOUN
can-1681	271	2	of	of	ADP
can-1681	271	3	tear	tear	ADJ
can-1681	271	4	film	film	NOUN
can-1681	271	5	:	:	PUNCT
can-1681	271	6	importance	importance	NOUN
can-1681	271	7	in	in	ADP
can-1681	271	8	homeostasis	homeostasis	NOUN
can-1681	271	9	and	and	CCONJ
can-1681	271	10	dysfunction	dysfunction	NOUN
can-1681	271	11	during	during	ADP
can-1681	271	12	disease	disease	NOUN
can-1681	271	13	.	.	PUNCT
can-1681	272	1	experimental	experimental	ADJ
can-1681	272	2	eye	eye	PROPN
can-1681	272	3	research	research	NOUN
can-1681	272	4	2013	2013	NUM
can-1681	272	5	;	;	PUNCT
can-1681	272	6	117	117	NUM
can-1681	272	7	:	:	PUNCT
can-1681	272	8	1–3	1–3	NUM
can-1681	272	9	.	.	NOUN
can-1681	272	10	12	12	NUM
can-1681	272	11	.	.	PUNCT
can-1681	273	1	shilpa	shilpa	PROPN
can-1681	273	2	g	g	PROPN
can-1681	273	3	,	,	PUNCT
can-1681	273	4	sandeep	sandeep	PROPN
can-1681	273	5	j.	j.	PROPN
can-1681	273	6	ocular	ocular	PROPN
can-1681	273	7	pharmacology	pharmacology	NOUN
can-1681	273	8	of	of	ADP
can-1681	273	9	tear	tear	ADJ
can-1681	273	10	film	film	NOUN
can-1681	273	11	,	,	PUNCT
can-1681	273	12	dry	dry	ADJ
can-1681	273	13	eye	eye	NOUN
can-1681	273	14	,	,	PUNCT
can-1681	273	15	and	and	CCONJ
can-1681	273	16	allergic	allergic	ADJ
can-1681	273	17	conjunctivitis	conjunctivitis	NOUN
can-1681	273	18	.	.	PUNCT
can-1681	274	1	in	in	ADP
can-1681	274	2	:	:	PUNCT
can-1681	274	3	whitcup	whitcup	PROPN
can-1681	274	4	s	s	PROPN
can-1681	274	5	,	,	PUNCT
can-1681	274	6	azar	azar	PROPN
can-1681	274	7	d	d	PROPN
can-1681	274	8	(	(	PUNCT
can-1681	274	9	editors	editor	NOUN
can-1681	274	10	)	)	PUNCT
can-1681	274	11	.	.	PUNCT
can-1681	275	1	pharmacologic	pharmacologic	ADJ
can-1681	275	2	therapy	therapy	NOUN
can-1681	275	3	of	of	ADP
can-1681	275	4	ocular	ocular	ADJ
can-1681	275	5	disease	disease	NOUN
can-1681	275	6	.	.	PUNCT
can-1681	276	1	handbook	handbook	VERB
can-1681	276	2	experimental	experimental	ADJ
can-1681	276	3	pharmaceutical	pharmaceutical	NOUN
can-1681	276	4	.	.	PUNCT
can-1681	277	1	germany	germany	PROPN
can-1681	277	2	:	:	PUNCT
can-1681	277	3	springer	springer	NOUN
can-1681	277	4	;	;	PUNCT
can-1681	277	5	2016	2016	NUM
can-1681	277	6	;	;	PUNCT
can-1681	277	7	p.	p.	PROPN
can-1681	277	8	97–118	97–118	NUM
can-1681	277	9	.	.	PROPN
can-1681	278	1	13	13	NUM
can-1681	278	2	.	.	PUNCT
can-1681	278	3	willcox	willcox	PROPN
can-1681	278	4	mdp	mdp	PROPN
can-1681	278	5	,	,	PUNCT
can-1681	278	6	argueso	argueso	NOUN
can-1681	278	7	p	p	NOUN
can-1681	278	8	,	,	PUNCT
can-1681	278	9	georgiev	georgiev	PROPN
can-1681	278	10	ga	ga	PROPN
can-1681	278	11	,	,	PUNCT
can-1681	278	12	et	et	PROPN
can-1681	278	13	al	al	PROPN
can-1681	278	14	.	.	PROPN
can-1681	279	1	tfos	tfos	PROPN
can-1681	279	2	dews	dews	PROPN
can-1681	279	3	ii	ii	PROPN
can-1681	279	4	tear	tear	ADJ
can-1681	279	5	film	film	NOUN
can-1681	279	6	report	report	NOUN
can-1681	279	7	.	.	PUNCT
can-1681	280	1	ocular	ocular	ADJ
can-1681	280	2	surface	surface	NOUN
can-1681	280	3	society	society	NOUN
can-1681	280	4	2017	2017	NUM
can-1681	280	5	;	;	PUNCT
can-1681	280	6	15(3	15(3	NUM
can-1681	280	7	):	):	PUNCT
can-1681	280	8	366–403	366–403	NUM
can-1681	280	9	.	.	PUNCT
can-1681	281	1	14	14	NUM
can-1681	281	2	.	.	PUNCT
can-1681	282	1	sridhar	sridhar	PROPN
can-1681	282	2	ms	ms	PROPN
can-1681	282	3	.	.	PROPN
can-1681	282	4	anatomy	anatomy	PROPN
can-1681	282	5	of	of	ADP
can-1681	282	6	cornea	cornea	NOUN
can-1681	282	7	and	and	CCONJ
can-1681	282	8	ocular	ocular	ADJ
can-1681	282	9	surface	surface	NOUN
can-1681	282	10	.	.	PUNCT
can-1681	283	1	indian	indian	ADJ
can-1681	283	2	journal	journal	PROPN
can-1681	283	3	of	of	ADP
can-1681	283	4	ophthalmology	ophthalmology	NOUN
can-1681	283	5	2018	2018	NUM
can-1681	283	6	;	;	PUNCT
can-1681	283	7	66(2	66(2	NUM
can-1681	283	8	):	):	PUNCT
can-1681	283	9	190	190	NUM
can-1681	283	10	–	–	SYM
can-1681	283	11	194	194	NUM
can-1681	283	12	.	.	PUNCT
can-1681	283	13	15	15	NUM
can-1681	283	14	.	.	PUNCT
can-1681	284	1	ma	ma	PROPN
can-1681	284	2	j	j	PROPN
can-1681	284	3	,	,	PUNCT
can-1681	284	4	wang	wang	PROPN
can-1681	284	5	y	y	PROPN
can-1681	284	6	,	,	PUNCT
can-1681	284	7	wei	wei	PROPN
can-1681	284	8	p	p	PROPN
can-1681	284	9	,	,	PUNCT
can-1681	284	10	et	et	PROPN
can-1681	284	11	al	al	PROPN
can-1681	284	12	.	.	PUNCT
can-1681	284	13	biomechanics	biomechanic	NOUN
can-1681	284	14	and	and	CCONJ
can-1681	284	15	structure	structure	NOUN
can-1681	284	16	of	of	ADP
can-1681	284	17	the	the	DET
can-1681	284	18	cornea	cornea	NOUN
can-1681	284	19	:	:	PUNCT
can-1681	284	20	implications	implication	NOUN
can-1681	284	21	and	and	CCONJ
can-1681	284	22	association	association	NOUN
can-1681	284	23	with	with	ADP
can-1681	284	24	corneal	corneal	ADJ
can-1681	284	25	disorders	disorder	NOUN
can-1681	284	26	.	.	PUNCT
can-1681	285	1	survey	survey	NOUN
can-1681	285	2	of	of	ADP
can-1681	285	3	ophthalmology	ophthalmology	NOUN
can-1681	285	4	2018	2018	NUM
can-1681	285	5	;	;	PUNCT
can-1681	285	6	63(6	63(6	NUM
can-1681	285	7	):	):	PUNCT
can-1681	285	8	851–861	851–861	NUM
can-1681	285	9	.	.	PUNCT
can-1681	286	1	16	16	NUM
can-1681	286	2	.	.	PUNCT
can-1681	287	1	williams	williams	PROPN
can-1681	287	2	k	k	PROPN
can-1681	287	3	,	,	PUNCT
can-1681	287	4	watsky	watsky	PROPN
can-1681	287	5	m.	m.	NOUN
can-1681	287	6	gap	gap	NOUN
can-1681	287	7	junctional	junctional	ADJ
can-1681	287	8	communication	communication	NOUN
can-1681	287	9	in	in	ADP
can-1681	287	10	the	the	DET
can-1681	287	11	human	human	ADJ
can-1681	287	12	corneal	corneal	ADJ
can-1681	287	13	endothelium	endothelium	NOUN
can-1681	287	14	and	and	CCONJ
can-1681	287	15	epithelium	epithelium	NOUN
can-1681	287	16	.	.	PUNCT
can-1681	288	1	current	current	ADJ
can-1681	288	2	eyes	eye	NOUN
can-1681	288	3	research	research	PROPN
can-1681	288	4	2002	2002	NUM
can-1681	288	5	;	;	PUNCT
can-1681	288	6	25(1	25(1	NUM
can-1681	288	7	):	):	PUNCT
can-1681	288	8	29–36	29–36	NUM
can-1681	288	9	.	.	PUNCT
can-1681	289	1	17	17	NUM
can-1681	289	2	.	.	PUNCT
can-1681	290	1	kling	kling	PROPN
can-1681	290	2	s	s	PROPN
can-1681	290	3	,	,	PUNCT
can-1681	290	4	hafezi	hafezi	PROPN
can-1681	290	5	f.	f.	PROPN
can-1681	290	6	corneal	corneal	PROPN
can-1681	290	7	biomechanics	biomechanic	NOUN
can-1681	290	8	—	—	PUNCT
can-1681	290	9	a	a	DET
can-1681	290	10	review	review	NOUN
can-1681	290	11	.	.	PUNCT
can-1681	291	1	ophthalmic	ophthalmic	ADJ
can-1681	291	2	and	and	CCONJ
can-1681	291	3	physiological	physiological	ADJ
can-1681	291	4	optics	optic	NOUN
can-1681	291	5	2017	2017	NUM
can-1681	291	6	;	;	PUNCT
can-1681	291	7	37(3	37(3	NUM
can-1681	291	8	):	):	PUNCT
can-1681	291	9	240–252	240–252	NUM
can-1681	291	10	.	.	PUNCT
can-1681	291	11	18	18	NUM
can-1681	291	12	.	.	PUNCT
can-1681	292	1	zavala	zavala	PROPN
can-1681	292	2	j	j	PROPN
can-1681	292	3	,	,	PUNCT
can-1681	292	4	lopez	lopez	PROPN
can-1681	292	5	jaime	jaime	PROPN
can-1681	292	6	gr	gr	PROPN
can-1681	292	7	,	,	PUNCT
can-1681	292	8	rodriguez	rodriguez	PROPN
can-1681	292	9	barrientos	barrientos	PROPN
can-1681	292	10	ca	ca	PROPN
can-1681	292	11	,	,	PUNCT
can-1681	292	12	et	et	PROPN
can-1681	292	13	al	al	PROPN
can-1681	292	14	.	.	PUNCT
can-1681	292	15	corneal	corneal	ADJ
can-1681	292	16	endothelium	endothelium	NOUN
can-1681	292	17	:	:	PUNCT
can-1681	292	18	developmental	developmental	ADJ
can-1681	292	19	strategies	strategy	NOUN
can-1681	292	20	for	for	ADP
can-1681	292	21	regeneration	regeneration	NOUN
can-1681	292	22	.	.	PUNCT
can-1681	293	1	eyes	eye	NOUN
can-1681	293	2	2013	2013	NUM
can-1681	293	3	;	;	PUNCT
can-1681	293	4	27(5	27(5	NOUN
can-1681	293	5	):	):	PUNCT
can-1681	293	6	579	579	NUM
can-1681	293	7	–	–	PUNCT
can-1681	293	8	588	588	NUM
can-1681	293	9	.	.	NOUN
can-1681	293	10	19	19	NUM
can-1681	293	11	.	.	PUNCT
can-1681	294	1	takahashi	takahashi	PROPN
can-1681	294	2	y	y	PROPN
can-1681	294	3	,	,	PUNCT
can-1681	294	4	watanabe	watanabe	PROPN
can-1681	294	5	a	a	PROPN
can-1681	294	6	,	,	PUNCT
can-1681	294	7	matsuda	matsuda	PROPN
can-1681	294	8	h	h	PROPN
can-1681	294	9	,	,	PUNCT
can-1681	294	10	et	et	PROPN
can-1681	294	11	al	al	PROPN
can-1681	294	12	.	.	PROPN
can-1681	294	13	anatomy	anatomy	NOUN
can-1681	294	14	of	of	ADP
can-1681	294	15	secretory	secretory	ADJ
can-1681	294	16	glands	gland	NOUN
can-1681	294	17	in	in	ADP
can-1681	294	18	the	the	DET
can-1681	294	19	eyelid	eyelid	NOUN
can-1681	294	20	and	and	CCONJ
can-1681	294	21	conjunctival	conjunctival	NOUN
can-1681	294	22	:	:	PUNCT
can-1681	294	23	a	a	DET
can-1681	294	24	photographic	photographic	ADJ
can-1681	294	25	review	review	NOUN
can-1681	294	26	.	.	PUNCT
can-1681	295	1	ophthalmic	ophthalmic	ADJ
can-1681	295	2	plastic	plastic	NOUN
can-1681	295	3	and	and	CCONJ
can-1681	295	4	reconstructive	reconstructive	ADJ
can-1681	295	5	surgery	surgery	NOUN
can-1681	295	6	2013	2013	NUM
can-1681	295	7	;	;	PUNCT
can-1681	295	8	29(3	29(3	NUM
can-1681	295	9	):	):	PUNCT
can-1681	295	10	215–219	215–219	NUM
can-1681	295	11	.	.	PUNCT
can-1681	296	1	20	20	NUM
can-1681	296	2	.	.	PUNCT
can-1681	297	1	gibson	gibson	PROPN
can-1681	297	2	ik	ik	PROPN
can-1681	297	3	.	.	PROPN
can-1681	297	4	goblet	goblet	NOUN
can-1681	297	5	cells	cell	NOUN
can-1681	297	6	of	of	ADP
can-1681	297	7	the	the	DET
can-1681	297	8	conjunctiva	conjunctiva	NOUN
can-1681	297	9	:	:	PUNCT
can-1681	297	10	a	a	DET
can-1681	297	11	review	review	NOUN
can-1681	297	12	of	of	ADP
can-1681	297	13	recent	recent	ADJ
can-1681	297	14	findings	finding	NOUN
can-1681	297	15	.	.	PUNCT
can-1681	298	1	progress	progress	NOUN
can-1681	298	2	in	in	ADP
can-1681	298	3	retinal	retinal	ADJ
can-1681	298	4	and	and	CCONJ
can-1681	298	5	eye	eye	NOUN
can-1681	298	6	research	research	NOUN
can-1681	298	7	2016	2016	NUM
can-1681	298	8	;	;	PUNCT
can-1681	298	9	54	54	NUM
can-1681	298	10	:	:	PUNCT
can-1681	298	11	49–63	49–63	NUM
can-1681	298	12	.	.	PUNCT
can-1681	299	1	21	21	NUM
can-1681	299	2	.	.	PUNCT
can-1681	300	1	galicia	galicia	PROPN
can-1681	300	2	-	-	PUNCT
can-1681	300	3	carreon	carreon	PROPN
can-1681	300	4	j	j	PROPN
can-1681	300	5	,	,	PUNCT
can-1681	300	6	santacruz	santacruz	PROPN
can-1681	300	7	c	c	PROPN
can-1681	300	8	,	,	PUNCT
can-1681	300	9	hong	hong	PROPN
can-1681	300	10	e	e	NOUN
can-1681	300	11	,	,	PUNCT
can-1681	300	12	et	et	PROPN
can-1681	300	13	al	al	PROPN
can-1681	300	14	.	.	PUNCT
can-1681	301	1	the	the	DET
can-1681	301	2	ocular	ocular	ADJ
can-1681	301	3	surface	surface	NOUN
can-1681	301	4	:	:	PUNCT
can-1681	301	5	from	from	ADP
can-1681	301	6	physiology	physiology	NOUN
can-1681	301	7	to	to	ADP
can-1681	301	8	the	the	DET
can-1681	301	9	ocular	ocular	ADJ
can-1681	301	10	allergic	allergic	ADJ
can-1681	301	11	diseases	disease	NOUN
can-1681	301	12	.	.	PUNCT
can-1681	302	1	revista	revista	PROPN
can-1681	302	2	alergia	alergia	NOUN
can-1681	302	3	mexico	mexico	PROPN
can-1681	302	4	2013	2013	NUM
can-1681	302	5	;	;	PUNCT
can-1681	302	6	60(4	60(4	NUM
can-1681	302	7	):	):	PUNCT
can-1681	302	8	172–183	172–183	NUM
can-1681	302	9	.	.	PUNCT
can-1681	303	1	22	22	NUM
can-1681	303	2	.	.	PUNCT
can-1681	304	1	watson	watson	PROPN
can-1681	304	2	pg	pg	PROPN
can-1681	304	3	,	,	PUNCT
can-1681	304	4	young	young	PROPN
can-1681	304	5	rd	rd	PROPN
can-1681	304	6	.	.	PUNCT
can-1681	304	7	scleral	scleral	ADJ
can-1681	304	8	structure	structure	NOUN
can-1681	304	9	,	,	PUNCT
can-1681	304	10	organization	organization	NOUN
can-1681	304	11	and	and	CCONJ
can-1681	304	12	disease	disease	NOUN
can-1681	304	13	.	.	PUNCT
can-1681	305	1	a	a	DET
can-1681	305	2	review	review	NOUN
can-1681	305	3	.	.	PUNCT
can-1681	306	1	experimental	experimental	ADJ
can-1681	306	2	eye	eye	PROPN
can-1681	306	3	research	research	PROPN
can-1681	306	4	2004	2004	NUM
can-1681	306	5	;	;	PUNCT
can-1681	307	1	78(3	78(3	NUM
can-1681	307	2	):	):	PUNCT
can-1681	307	3	609–623	609–623	NUM
can-1681	307	4	.	.	PUNCT
can-1681	308	1	http://www.who.int/es/news-room/fact-sheets/detail/blindness-and-vi-sual-impairment	http://www.who.int/es/news-room/fact-sheets/detail/blindness-and-vi-sual-impairment	NOUN
can-1681	308	2	76	76	NUM
can-1681	308	3	23	23	NUM
can-1681	308	4	.	.	PUNCT
can-1681	309	1	davis	davis	PROPN
can-1681	309	2	-	-	PUNCT
can-1681	309	3	silberman	silberman	PROPN
can-1681	309	4	n	n	CCONJ
can-1681	309	5	,	,	PUNCT
can-1681	309	6	ashery	ashery	PROPN
can-1681	309	7	-	-	PUNCT
can-1681	309	8	padan	padan	PROPN
can-1681	309	9	r.	r.	PROPN
can-1681	309	10	iris	iris	PROPN
can-1681	309	11	development	development	PROPN
can-1681	309	12	in	in	ADP
can-1681	309	13	vertebrates	vertebrate	NOUN
can-1681	309	14	;	;	PUNCT
can-1681	309	15	genetic	genetic	ADJ
can-1681	309	16	and	and	CCONJ
can-1681	309	17	molecular	molecular	ADJ
can-1681	309	18	considerations	consideration	NOUN
can-1681	309	19	.	.	PUNCT
can-1681	310	1	brain	brain	NOUN
can-1681	310	2	research	research	NOUN
can-1681	310	3	2008	2008	NUM
can-1681	310	4	;	;	PUNCT
can-1681	310	5	1192	1192	NUM
can-1681	310	6	:	:	PUNCT
can-1681	310	7	17–28	17–28	NUM
can-1681	310	8	.	.	PROPN
can-1681	310	9	24	24	NUM
can-1681	310	10	.	.	PUNCT
can-1681	311	1	civan	civan	PROPN
can-1681	311	2	mm	mm	PROPN
can-1681	311	3	,	,	PUNCT
can-1681	311	4	macknight	macknight	NOUN
can-1681	311	5	ad	ad	NOUN
can-1681	311	6	.	.	PUNCT
can-1681	312	1	the	the	DET
can-1681	312	2	ins	in	NOUN
can-1681	312	3	and	and	CCONJ
can-1681	312	4	outs	out	NOUN
can-1681	312	5	of	of	ADP
can-1681	312	6	aueous	aueous	ADJ
can-1681	312	7	humour	humour	NOUN
can-1681	312	8	secretion	secretion	NOUN
can-1681	312	9	.	.	PUNCT
can-1681	313	1	experimental	experimental	ADJ
can-1681	313	2	eye	eye	PROPN
can-1681	313	3	research	research	PROPN
can-1681	313	4	2004	2004	NUM
can-1681	313	5	;	;	PUNCT
can-1681	314	1	78(3	78(3	NUM
can-1681	314	2	):	):	PUNCT
can-1681	314	3	625–631	625–631	NUM
can-1681	314	4	.	.	PUNCT
can-1681	315	1	25	25	NUM
can-1681	315	2	.	.	PUNCT
can-1681	316	1	aliancy	aliancy	PROPN
can-1681	316	2	jf	jf	PROPN
can-1681	316	3	,	,	PUNCT
can-1681	316	4	mamalis	mamalis	PROPN
can-1681	316	5	n	n	CCONJ
can-1681	316	6	,	,	PUNCT
can-1681	316	7	et	et	PROPN
can-1681	316	8	al	al	PROPN
can-1681	316	9	.	.	PUNCT
can-1681	316	10	webvision	webvision	PROPN
can-1681	316	11	:	:	PUNCT
can-1681	316	12	the	the	DET
can-1681	316	13	organization	organization	NOUN
can-1681	316	14	of	of	ADP
can-1681	316	15	the	the	DET
can-1681	316	16	retina	retina	NOUN
can-1681	316	17	and	and	CCONJ
can-1681	316	18	visual	visual	ADJ
can-1681	316	19	system	system	NOUN
can-1681	316	20	.	.	PUNCT
can-1681	317	1	in	in	ADP
can-1681	317	2	:	:	PUNCT
can-1681	317	3	kolb	kolb	PROPN
can-1681	317	4	h	h	PROPN
can-1681	317	5	,	,	PUNCT
can-1681	317	6	fernandez	fernandez	PROPN
can-1681	317	7	e	e	PROPN
can-1681	317	8	,	,	PUNCT
can-1681	317	9	nelson	nelson	PROPN
can-1681	317	10	r	r	PROPN
can-1681	317	11	(	(	PUNCT
can-1681	317	12	editors	editor	NOUN
can-1681	317	13	)	)	PUNCT
can-1681	317	14	.	.	PUNCT
can-1681	318	1	webvision	webvision	NOUN
can-1681	318	2	:	:	PUNCT
can-1681	318	3	the	the	DET
can-1681	318	4	organization	organization	NOUN
can-1681	318	5	of	of	ADP
can-1681	318	6	the	the	DET
can-1681	318	7	retina	retina	NOUN
can-1681	318	8	and	and	CCONJ
can-1681	318	9	visual	visual	ADJ
can-1681	318	10	system	system	NOUN
can-1681	318	11	.	.	PUNCT
can-1681	319	1	salt	salt	PROPN
can-1681	319	2	lake	lake	PROPN
can-1681	319	3	city	city	PROPN
can-1681	319	4	ut	ut	PROPN
can-1681	319	5	:	:	PUNCT
can-1681	319	6	webvision	webvision	PROPN
can-1681	319	7	;	;	PUNCT
can-1681	319	8	2017	2017	NUM
can-1681	319	9	.	.	PUNCT
can-1681	320	1	26	26	NUM
can-1681	320	2	.	.	PUNCT
can-1681	321	1	assia	assia	PROPN
can-1681	321	2	ei	ei	PROPN
can-1681	321	3	,	,	PUNCT
can-1681	321	4	apple	apple	NOUN
can-1681	321	5	dj	dj	NOUN
can-1681	321	6	.	.	PUNCT
can-1681	321	7	side	side	NOUN
can-1681	321	8	-	-	PUNCT
can-1681	321	9	view	view	NOUN
can-1681	321	10	analysis	analysis	NOUN
can-1681	321	11	of	of	ADP
can-1681	321	12	lens	len	NOUN
can-1681	321	13	.	.	PUNCT
can-1681	322	1	ⅰ.	ⅰ.	NOUN
can-1681	323	1	the	the	DET
can-1681	323	2	crystalline	crystalline	ADJ
can-1681	323	3	lens	lens	NOUN
can-1681	323	4	and	and	CCONJ
can-1681	323	5	the	the	DET
can-1681	323	6	evacuated	evacuate	VERB
can-1681	323	7	bag	bag	NOUN
can-1681	323	8	.	.	PUNCT
can-1681	324	1	arch	arch	ADJ
can-1681	324	2	ophthalmol	ophthalmol	PROPN
can-1681	324	3	1992	1992	NUM
can-1681	324	4	;	;	PUNCT
can-1681	324	5	110(1	110(1	NUM
can-1681	324	6	):	):	PUNCT
can-1681	324	7	89–93	89–93	NUM
can-1681	324	8	.	.	PUNCT
can-1681	325	1	27	27	NUM
can-1681	325	2	.	.	PUNCT
can-1681	326	1	nickla	nickla	PROPN
can-1681	326	2	dl	dl	PROPN
can-1681	326	3	,	,	PUNCT
can-1681	326	4	wallman	wallman	NOUN
can-1681	326	5	j.	j.	PROPN
can-1681	326	6	the	the	DET
can-1681	326	7	multifunctional	multifunctional	PROPN
can-1681	326	8	choroid	choroid	NOUN
can-1681	326	9	.	.	PUNCT
can-1681	327	1	progress	progress	NOUN
can-1681	327	2	in	in	ADP
can-1681	327	3	retinal	retinal	ADJ
can-1681	327	4	and	and	CCONJ
can-1681	327	5	eye	eye	NOUN
can-1681	327	6	research	research	NOUN
can-1681	327	7	2010	2010	NUM
can-1681	327	8	;	;	PUNCT
can-1681	327	9	29(2	29(2	NUM
can-1681	327	10	):	):	PUNCT
can-1681	327	11	144–168	144–168	NUM
can-1681	327	12	.	.	PUNCT
can-1681	328	1	28	28	NUM
can-1681	328	2	.	.	PUNCT
can-1681	329	1	mains	main	VERB
can-1681	329	2	j	j	PROPN
can-1681	329	3	,	,	PUNCT
can-1681	329	4	wilson	wilson	PROPN
can-1681	329	5	cg	cg	PROPN
can-1681	329	6	.	.	PUNCT
can-1681	330	1	the	the	DET
can-1681	330	2	vitreous	vitreous	ADJ
can-1681	330	3	humor	humor	NOUN
can-1681	330	4	as	as	ADP
can-1681	330	5	a	a	DET
can-1681	330	6	barrier	barrier	NOUN
can-1681	330	7	to	to	PART
can-1681	330	8	nanoparticle	nanoparticle	VERB
can-1681	330	9	distribution	distribution	NOUN
can-1681	330	10	.	.	PUNCT
can-1681	331	1	journal	journal	NOUN
can-1681	331	2	of	of	ADP
can-1681	331	3	ocular	ocular	ADJ
can-1681	331	4	pharmacology	pharmacology	NOUN
can-1681	331	5	and	and	CCONJ
can-1681	331	6	therapeutics	therapeutic	NOUN
can-1681	331	7	2013	2013	NUM
can-1681	331	8	;	;	PUNCT
can-1681	331	9	29(2	29(2	NUM
can-1681	331	10	):	):	PUNCT
can-1681	331	11	143	143	NUM
can-1681	331	12	–	–	SYM
can-1681	331	13	150	150	NUM
can-1681	331	14	.	.	X
can-1681	331	15	29	29	NUM
can-1681	331	16	.	.	PUNCT
can-1681	332	1	mulla	mulla	PROPN
can-1681	332	2	a	a	PRON
can-1681	332	3	,	,	PUNCT
can-1681	332	4	massey	massey	PROPN
can-1681	332	5	kl	kl	PROPN
can-1681	332	6	,	,	PUNCT
can-1681	332	7	kalra	kalra	PROPN
can-1681	332	8	j.	j.	PROPN
can-1681	332	9	vitreous	vitreous	ADJ
can-1681	332	10	humor	humor	NOUN
can-1681	332	11	biochemical	biochemical	ADJ
can-1681	332	12	constituents	constituent	NOUN
can-1681	332	13	:	:	PUNCT
can-1681	332	14	evaluation	evaluation	NOUN
can-1681	332	15	of	of	ADP
can-1681	332	16	between	between	ADP
can-1681	332	17	-	-	PUNCT
can-1681	332	18	eye	eye	NOUN
can-1681	332	19	differences	difference	NOUN
can-1681	332	20	.	.	PUNCT
can-1681	333	1	the	the	DET
can-1681	333	2	american	american	PROPN
can-1681	333	3	journal	journal	PROPN
can-1681	333	4	of	of	ADP
can-1681	333	5	forensic	forensic	ADJ
can-1681	333	6	medicine	medicine	NOUN
can-1681	333	7	and	and	CCONJ
can-1681	333	8	pathology	pathology	NOUN
can-1681	333	9	2005	2005	NUM
can-1681	333	10	;	;	PUNCT
can-1681	333	11	26(2	26(2	NUM
can-1681	333	12	):	):	PUNCT
can-1681	333	13	146–149	146–149	NUM
can-1681	333	14	.	.	NOUN
can-1681	333	15	30	30	NUM
can-1681	333	16	.	.	PUNCT
can-1681	334	1	murthy	murthy	PROPN
can-1681	334	2	kr	kr	PROPN
can-1681	334	3	,	,	PUNCT
can-1681	334	4	goel	goel	PROPN
can-1681	334	5	r	r	PROPN
can-1681	334	6	,	,	PUNCT
can-1681	334	7	subbannayya	subbannayya	PROPN
can-1681	334	8	y	y	PROPN
can-1681	334	9	,	,	PUNCT
can-1681	334	10	et	et	PROPN
can-1681	334	11	al	al	PROPN
can-1681	334	12	.	.	PROPN
can-1681	335	1	proteomic	proteomic	ADJ
can-1681	335	2	analysis	analysis	NOUN
can-1681	335	3	of	of	ADP
can-1681	335	4	human	human	ADJ
can-1681	335	5	vitreous	vitreous	ADJ
can-1681	335	6	humor	humor	NOUN
can-1681	335	7	.	.	PUNCT
can-1681	336	1	clinical	clinical	ADJ
can-1681	336	2	proteomics	proteomic	NOUN
can-1681	336	3	2014	2014	NUM
can-1681	336	4	;	;	PUNCT
can-1681	336	5	11(1	11(1	NUM
can-1681	336	6	):	):	PUNCT
can-1681	336	7	29	29	NUM
can-1681	336	8	.	.	X
can-1681	336	9	31	31	NUM
can-1681	336	10	.	.	PUNCT
can-1681	337	1	willoughby	willoughby	PROPN
can-1681	337	2	ce	ce	PROPN
can-1681	337	3	,	,	PUNCT
can-1681	337	4	ponzin	ponzin	PROPN
can-1681	337	5	d	d	PROPN
can-1681	337	6	,	,	PUNCT
can-1681	337	7	ferrari	ferrari	PROPN
can-1681	337	8	s	s	PART
can-1681	337	9	,	,	PUNCT
can-1681	337	10	et	et	PROPN
can-1681	337	11	al	al	PROPN
can-1681	337	12	.	.	PROPN
can-1681	337	13	anatomy	anatomy	PROPN
can-1681	337	14	and	and	CCONJ
can-1681	337	15	physiology	physiology	NOUN
can-1681	337	16	of	of	ADP
can-1681	337	17	the	the	DET
can-1681	337	18	human	human	ADJ
can-1681	337	19	eye	eye	NOUN
can-1681	337	20	:	:	PUNCT
can-1681	337	21	effects	effect	NOUN
can-1681	337	22	of	of	ADP
can-1681	337	23	mucopolysaccharidoses	mucopolysaccharidose	NOUN
can-1681	337	24	disease	disease	NOUN
can-1681	337	25	on	on	ADP
can-1681	337	26	structure	structure	NOUN
can-1681	337	27	and	and	CCONJ
can-1681	337	28	function	function	NOUN
can-1681	337	29	—	—	PUNCT
can-1681	337	30	a	a	DET
can-1681	337	31	review	review	NOUN
can-1681	337	32	.	.	PUNCT
can-1681	338	1	clinical	clinical	ADJ
can-1681	338	2	&	&	CCONJ
can-1681	338	3	experimental	experimental	ADJ
can-1681	338	4	ophthalmology	ophthalmology	NOUN
can-1681	338	5	2010	2010	NUM
can-1681	338	6	;	;	PUNCT
can-1681	338	7	38(s1	38(s1	NUM
can-1681	338	8	):	):	PUNCT
can-1681	338	9	2–11	2–11	NOUN
can-1681	338	10	.	.	PUNCT
can-1681	339	1	32	32	NUM
can-1681	339	2	.	.	PUNCT
can-1681	340	1	simo	simo	PROPN
can-1681	340	2	r	r	PROPN
can-1681	340	3	,	,	PUNCT
can-1681	340	4	villarroel	villarroel	PROPN
can-1681	340	5	m	m	NOUN
can-1681	340	6	,	,	PUNCT
can-1681	340	7	corraliza	corraliza	ADJ
can-1681	340	8	l	l	NOUN
can-1681	340	9	,	,	PUNCT
can-1681	340	10	et	et	PROPN
can-1681	340	11	al	al	PROPN
can-1681	340	12	.	.	PUNCT
can-1681	341	1	the	the	DET
can-1681	341	2	retinal	retinal	ADJ
can-1681	341	3	pigment	pigment	NOUN
can-1681	341	4	epithelium	epithelium	NOUN
can-1681	341	5	:	:	PUNCT
can-1681	341	6	something	something	PRON
can-1681	341	7	more	more	ADJ
can-1681	341	8	than	than	ADP
can-1681	341	9	a	a	DET
can-1681	341	10	constituent	constituent	NOUN
can-1681	341	11	of	of	ADP
can-1681	341	12	the	the	DET
can-1681	341	13	blood	blood	NOUN
can-1681	341	14	-	-	PUNCT
can-1681	341	15	retinal	retinal	ADJ
can-1681	341	16	barrier	barrier	NOUN
can-1681	341	17	—	—	PUNCT
can-1681	341	18	the	the	DET
can-1681	341	19	implications	implication	NOUN
can-1681	341	20	for	for	ADP
can-1681	341	21	the	the	DET
can-1681	341	22	pathogenesis	pathogenesis	NOUN
can-1681	341	23	of	of	ADP
can-1681	341	24	diabetic	diabetic	ADJ
can-1681	341	25	retinopathy	retinopathy	NOUN
can-1681	341	26	.	.	PUNCT
can-1681	342	1	journal	journal	NOUN
can-1681	342	2	of	of	ADP
can-1681	342	3	biotechnology	biotechnology	NOUN
can-1681	342	4	2010	2010	NUM
can-1681	342	5	;	;	PUNCT
can-1681	342	6	2010	2010	NUM
can-1681	342	7	:	:	PUNCT
can-1681	342	8	190724	190724	NUM
can-1681	342	9	.	.	PUNCT
can-1681	343	1	33	33	NUM
can-1681	343	2	.	.	PUNCT
can-1681	344	1	strauss	strauss	PROPN
can-1681	344	2	o.	o.	PROPN
can-1681	345	1	the	the	DET
can-1681	345	2	retinal	retinal	ADJ
can-1681	345	3	pigment	pigment	NOUN
can-1681	345	4	epithelium	epithelium	NOUN
can-1681	345	5	in	in	ADP
can-1681	345	6	visual	visual	ADJ
can-1681	345	7	function	function	NOUN
can-1681	345	8	.	.	PUNCT
can-1681	346	1	physiological	physiological	ADJ
can-1681	346	2	reviews	review	NOUN
can-1681	346	3	2005	2005	NUM
can-1681	346	4	;	;	PUNCT
can-1681	346	5	85(3	85(3	NUM
can-1681	346	6	):	):	PUNCT
can-1681	346	7	845	845	NUM
can-1681	346	8	–	–	PUNCT
can-1681	346	9	881	881	NUM
can-1681	346	10	.	.	PUNCT
can-1681	346	11	34	34	NUM
can-1681	346	12	.	.	PUNCT
can-1681	347	1	sparrow	sparrow	PROPN
can-1681	347	2	jr	jr	PROPN
can-1681	347	3	,	,	PUNCT
can-1681	347	4	hicks	hicks	PROPN
can-1681	347	5	d	d	PROPN
can-1681	347	6	,	,	PUNCT
can-1681	347	7	hamel	hamel	PROPN
can-1681	347	8	cp	cp	PROPN
can-1681	347	9	.	.	PUNCT
can-1681	348	1	the	the	DET
can-1681	348	2	retinal	retinal	ADJ
can-1681	348	3	pigment	pigment	NOUN
can-1681	348	4	epithelium	epithelium	NOUN
can-1681	348	5	in	in	ADP
can-1681	348	6	health	health	NOUN
can-1681	348	7	and	and	CCONJ
can-1681	348	8	disease	disease	NOUN
can-1681	348	9	.	.	PUNCT
can-1681	349	1	current	current	ADJ
can-1681	349	2	molecular	molecular	ADJ
can-1681	349	3	medicine	medicine	NOUN
can-1681	349	4	2010	2010	NUM
can-1681	349	5	;	;	PUNCT
can-1681	349	6	10(9	10(9	NUM
can-1681	349	7	):	):	PUNCT
can-1681	349	8	802–823	802–823	NUM
can-1681	349	9	.	.	PUNCT
can-1681	349	10	35	35	NUM
can-1681	349	11	.	.	PUNCT
can-1681	350	1	boulton	boulton	PROPN
can-1681	350	2	m	m	PROPN
can-1681	350	3	,	,	PUNCT
can-1681	350	4	dayhaw	dayhaw	PROPN
can-1681	350	5	-	-	PUNCT
can-1681	350	6	barker	barker	NOUN
can-1681	350	7	p.	p.	NOUN
can-1681	351	1	the	the	DET
can-1681	351	2	role	role	NOUN
can-1681	351	3	of	of	ADP
can-1681	351	4	retinal	retinal	ADJ
can-1681	351	5	pigment	pigment	NOUN
can-1681	351	6	epithelium	epithelium	NOUN
can-1681	351	7	:	:	PUNCT
can-1681	351	8	topographical	topographical	ADJ
can-1681	351	9	variation	variation	NOUN
can-1681	351	10	and	and	CCONJ
can-1681	351	11	ageing	age	VERB
can-1681	351	12	changes	change	NOUN
can-1681	351	13	.	.	PUNCT
can-1681	352	1	eyes	eye	NOUN
can-1681	352	2	2001	2001	NUM
can-1681	352	3	;	;	PUNCT
can-1681	352	4	15(part	15(part	NUM
can-1681	352	5	3	3	NUM
can-1681	352	6	):	):	PUNCT
can-1681	352	7	384–389	384–389	NUM
can-1681	352	8	.	.	PUNCT
can-1681	352	9	36	36	NUM
can-1681	352	10	.	.	PUNCT
can-1681	353	1	gupta	gupta	PROPN
can-1681	353	2	mp	mp	PROPN
can-1681	353	3	,	,	PUNCT
can-1681	353	4	herzlich	herzlich	PROPN
can-1681	353	5	aa	aa	PROPN
can-1681	353	6	,	,	PUNCT
can-1681	353	7	sauer	sauer	PROPN
can-1681	353	8	t	t	PROPN
can-1681	353	9	,	,	PUNCT
can-1681	353	10	et	et	PROPN
can-1681	353	11	al	al	PROPN
can-1681	353	12	.	.	PUNCT
can-1681	353	13	retinal	retinal	ADJ
can-1681	353	14	anatomy	anatomy	NOUN
can-1681	353	15	and	and	CCONJ
can-1681	353	16	pathology	pathology	NOUN
can-1681	353	17	.	.	PUNCT
can-1681	354	1	develop	develop	VERB
can-1681	354	2	ophthalmology	ophthalmology	NOUN
can-1681	354	3	2016	2016	NUM
can-1681	354	4	;	;	PUNCT
can-1681	354	5	55	55	NUM
can-1681	354	6	:	:	PUNCT
can-1681	355	1	7–17	7–17	NUM
can-1681	355	2	.	.	PUNCT
can-1681	356	1	37	37	NUM
can-1681	356	2	.	.	PUNCT
can-1681	357	1	harris	harris	PROPN
can-1681	357	2	a	a	PROPN
can-1681	357	3	,	,	PUNCT
can-1681	357	4	ciulla	ciulla	PROPN
can-1681	357	5	ta	ta	PROPN
can-1681	357	6	,	,	PUNCT
can-1681	357	7	chung	chung	PROPN
can-1681	357	8	hs	hs	PROPN
can-1681	357	9	,	,	PUNCT
can-1681	357	10	et	et	PROPN
can-1681	357	11	al	al	PROPN
can-1681	357	12	.	.	PUNCT
can-1681	358	1	regulation	regulation	NOUN
can-1681	358	2	of	of	ADP
can-1681	358	3	retinal	retinal	ADJ
can-1681	358	4	and	and	CCONJ
can-1681	358	5	optic	optic	ADJ
can-1681	358	6	nerve	nerve	NOUN
can-1681	358	7	blood	blood	NOUN
can-1681	358	8	flow	flow	NOUN
can-1681	358	9	.	.	PUNCT
can-1681	359	1	arch	arch	ADJ
can-1681	359	2	ophthalmol	ophthalmol	PROPN
can-1681	359	3	1998	1998	NUM
can-1681	359	4	;	;	PUNCT
can-1681	359	5	116(11	116(11	NUM
can-1681	359	6	):	):	PUNCT
can-1681	359	7	1491–1495	1491–1495	NUM
can-1681	359	8	.	.	PUNCT
can-1681	360	1	38	38	NUM
can-1681	360	2	.	.	PUNCT
can-1681	361	1	gómez	gómez	NOUN
can-1681	361	2	m.	m.	NOUN
can-1681	361	3	nanomaterials	nanomaterial	NOUN
can-1681	361	4	,	,	PUNCT
can-1681	361	5	nanoparticles	nanoparticle	NOUN
can-1681	361	6	and	and	CCONJ
can-1681	361	7	green	green	ADJ
can-1681	361	8	synthesis	synthesis	NOUN
can-1681	361	9	(	(	PUNCT
can-1681	361	10	in	in	ADP
can-1681	361	11	spanish	spanish	ADJ
can-1681	361	12	)	)	PUNCT
can-1681	361	13	.	.	PUNCT
can-1681	362	1	medicina	medicina	PROPN
can-1681	362	2	y	y	PROPN
can-1681	362	3	cirugia	cirugia	PROPN
can-1681	362	4	2018	2018	NUM
can-1681	362	5	;	;	PUNCT
can-1681	362	6	27(2	27(2	NUM
can-1681	362	7	):	):	PUNCT
can-1681	362	8	75–80	75–80	PROPN
can-1681	362	9	.	.	PROPN
can-1681	362	10	39	39	NUM
can-1681	362	11	.	.	PUNCT
can-1681	363	1	weng	weng	PROPN
can-1681	363	2	y	y	PROPN
can-1681	363	3	,	,	PUNCT
can-1681	363	4	liu	liu	PROPN
can-1681	363	5	j	j	PROPN
can-1681	363	6	,	,	PUNCT
can-1681	363	7	jin	jin	PROPN
can-1681	363	8	s	s	PROPN
can-1681	363	9	,	,	PUNCT
can-1681	363	10	et	et	PROPN
can-1681	363	11	al	al	PROPN
can-1681	363	12	.	.	PUNCT
can-1681	364	1	nanotechnology	nanotechnology	PROPN
can-1681	364	2	-	-	PUNCT
can-1681	364	3	based	base	VERB
can-1681	364	4	strategies	strategy	NOUN
can-1681	364	5	for	for	ADP
can-1681	364	6	treatment	treatment	NOUN
can-1681	364	7	of	of	ADP
can-1681	364	8	ocular	ocular	ADJ
can-1681	364	9	disease	disease	NOUN
can-1681	364	10	.	.	PUNCT
can-1681	365	1	acta	acta	PROPN
can-1681	365	2	pharmaceutica	pharmaceutica	PROPN
can-1681	365	3	sinica	sinica	PROPN
can-1681	365	4	b	b	PROPN
can-1681	365	5	2016	2016	NUM
can-1681	365	6	;	;	PUNCT
can-1681	365	7	7(3	7(3	NUM
can-1681	365	8	):	):	PUNCT
can-1681	365	9	281–291	281–291	NUM
can-1681	365	10	.	.	PUNCT
can-1681	365	11	40	40	NUM
can-1681	365	12	.	.	PUNCT
can-1681	366	1	prakash	prakash	PROPN
can-1681	366	2	m	m	PROPN
can-1681	366	3	,	,	PUNCT
can-1681	366	4	dhesingh	dhesingh	ADJ
can-1681	366	5	rs	r	NOUN
can-1681	366	6	.	.	PUNCT
can-1681	367	1	nanoparticles	nanoparticle	NOUN
can-1681	367	2	modified	modify	VERB
can-1681	367	3	drug	drug	NOUN
can-1681	367	4	loaded	load	VERB
can-1681	367	5	biodegradable	biodegradable	ADJ
can-1681	367	6	polymeric	polymeric	ADJ
can-1681	367	7	contact	contact	NOUN
can-1681	367	8	lenses	lense	NOUN
can-1681	367	9	for	for	ADP
can-1681	367	10	sustainable	sustainable	ADJ
can-1681	367	11	ocular	ocular	ADJ
can-1681	367	12	drug	drug	NOUN
can-1681	367	13	delivery	delivery	NOUN
can-1681	367	14	.	.	PUNCT
can-1681	368	1	current	current	ADJ
can-1681	368	2	drug	drug	NOUN
can-1681	368	3	delivery	delivery	NOUN
can-1681	368	4	2017	2017	NUM
can-1681	368	5	;	;	PUNCT
can-1681	368	6	14(4	14(4	NUM
can-1681	368	7	):	):	PUNCT
can-1681	368	8	555–565	555–565	NUM
can-1681	368	9	.	.	NOUN
can-1681	368	10	41	41	NUM
can-1681	368	11	.	.	PUNCT
can-1681	369	1	yavuz	yavuz	PROPN
can-1681	369	2	b	b	PROPN
can-1681	369	3	,	,	PUNCT
can-1681	369	4	bozdag	bozdag	PROPN
can-1681	369	5	pehlivan	pehlivan	PROPN
can-1681	369	6	s	s	PROPN
can-1681	369	7	,	,	PUNCT
can-1681	369	8	kaffashi	kaffashi	PROPN
can-1681	369	9	a	a	PROPN
can-1681	369	10	,	,	PUNCT
can-1681	369	11	et	et	PROPN
can-1681	369	12	al	al	PROPN
can-1681	369	13	.	.	PROPN
can-1681	370	1	in	in	ADP
can-1681	370	2	vivo	vivo	ADJ
can-1681	370	3	tissue	tissue	NOUN
can-1681	370	4	distribution	distribution	NOUN
can-1681	370	5	and	and	CCONJ
can-1681	370	6	efficacy	efficacy	NOUN
can-1681	370	7	studies	study	NOUN
can-1681	370	8	for	for	ADP
can-1681	370	9	cyclosporin	cyclosporin	NOUN
can-1681	370	10	a	a	DET
can-1681	370	11	loaded	load	VERB
can-1681	370	12	nano	nano	NOUN
can-1681	370	13	-	-	PUNCT
can-1681	370	14	decorated	decorate	VERB
can-1681	370	15	subconjunctival	subconjunctival	NOUN
can-1681	370	16	implants	implant	NOUN
can-1681	370	17	comparative	comparative	ADJ
can-1681	370	18	study	study	NOUN
can-1681	370	19	of	of	ADP
can-1681	370	20	human	human	ADJ
can-1681	370	21	embryonic	embryonic	ADJ
can-1681	370	22	stem	stem	NOUN
can-1681	370	23	cells	cell	NOUN
can-1681	370	24	(	(	PUNCT
can-1681	370	25	hesc	hesc	PROPN
can-1681	370	26	)	)	PUNCT
can-1681	370	27	and	and	CCONJ
can-1681	370	28	human	human	ADJ
can-1681	370	29	induced	induced	ADJ
can-1681	370	30	pluripotent	pluripotent	ADJ
can-1681	370	31	stem	stem	NOUN
can-1681	370	32	cells	cell	NOUN
can-1681	370	33	(	(	PUNCT
can-1681	370	34	hipsc	hipsc	ADJ
can-1681	370	35	)	)	PUNCT
can-1681	370	36	as	as	ADP
can-1681	370	37	a	a	DET
can-1681	370	38	treatment	treatment	NOUN
can-1681	370	39	for	for	ADP
can-1681	370	40	retinal	retinal	ADJ
can-1681	370	41	dystrophies	dystrophy	NOUN
can-1681	370	42	.	.	PUNCT
can-1681	371	1	drug	drug	NOUN
can-1681	371	2	delivery	delivery	NOUN
can-1681	371	3	2016	2016	NUM
can-1681	371	4	:	:	PUNCT
can-1681	372	1	3279–3284	3279–3284	NUM
can-1681	372	2	.	.	PUNCT
can-1681	373	1	42	42	NUM
can-1681	373	2	.	.	PUNCT
can-1681	374	1	pehlivan	pehlivan	PROPN
can-1681	374	2	sb	sb	PROPN
can-1681	374	3	,	,	PUNCT
can-1681	374	4	yavuz	yavuz	PROPN
can-1681	374	5	b	b	PROPN
can-1681	374	6	,	,	PUNCT
can-1681	374	7	calamak	calamak	PROPN
can-1681	374	8	s.	s.	PROPN
can-1681	374	9	preparation	preparation	PROPN
can-1681	374	10	and	and	CCONJ
can-1681	374	11	in	in	ADP
can-1681	374	12	vivo	vivo	NOUN
can-1681	374	13	/	/	SYM
can-1681	374	14	in	in	ADP
can-1681	374	15	vivo	vivo	ADJ
can-1681	374	16	evaluation	evaluation	NOUN
can-1681	374	17	of	of	ADP
can-1681	374	18	cyclosporin	cyclosporin	NOUN
can-1681	374	19	a	a	ADV
can-1681	374	20	-	-	PUNCT
can-1681	374	21	loaded	load	VERB
can-1681	374	22	nanodecorated	nanodecorated	ADJ
can-1681	374	23	ocular	ocular	ADJ
can-1681	374	24	implants	implant	NOUN
can-1681	374	25	for	for	ADP
can-1681	374	26	subconjunctival	subconjunctival	ADJ
can-1681	374	27	application	application	NOUN
can-1681	374	28	.	.	PUNCT
can-1681	375	1	journal	journal	NOUN
can-1681	375	2	of	of	ADP
can-1681	375	3	pharmaceutical	pharmaceutical	NOUN
can-1681	375	4	science	science	NOUN
can-1681	375	5	2015	2015	NUM
can-1681	375	6	;	;	PUNCT
can-1681	375	7	104(5	104(5	NUM
can-1681	375	8	):	):	PUNCT
can-1681	375	9	1709–1720	1709–1720	NUM
can-1681	375	10	.	.	PUNCT
can-1681	376	1	43	43	NUM
can-1681	376	2	.	.	PUNCT
can-1681	377	1	li	li	PROPN
can-1681	377	2	x	x	PROPN
can-1681	377	3	,	,	PUNCT
can-1681	377	4	zhang	zhang	PROPN
can-1681	377	5	z	z	PROPN
can-1681	377	6	,	,	PUNCT
can-1681	377	7	chen	chen	PROPN
can-1681	377	8	h.	h.	PROPN
can-1681	377	9	preparation	preparation	NOUN
can-1681	377	10	and	and	CCONJ
can-1681	377	11	evaluation	evaluation	NOUN
can-1681	377	12	of	of	ADP
can-1681	377	13	diclofenac	diclofenac	ADJ
can-1681	377	14	ophthalmic	ophthalmic	ADJ
can-1681	377	15	rapid	rapid	ADJ
can-1681	377	16	prototyping	prototyping	NOUN
can-1681	377	17	nanocomposite	nanocomposite	PROPN
can-1681	377	18	gel	gel	NOUN
can-1681	377	19	.	.	PUNCT
can-1681	378	1	international	international	ADJ
can-1681	378	2	pharmaceutical	pharmaceutical	ADJ
can-1681	378	3	company	company	NOUN
can-1681	378	4	2013	2013	NUM
can-1681	378	5	;	;	PUNCT
can-1681	378	6	448(1	448(1	NUM
can-1681	378	7	):	):	PUNCT
can-1681	378	8	96–100	96–100	NUM
can-1681	378	9	.	.	PUNCT
can-1681	378	10	44	44	NUM
can-1681	378	11	.	.	PUNCT
can-1681	379	1	li	li	PROPN
can-1681	379	2	x	x	PROPN
can-1681	379	3	,	,	PUNCT
can-1681	379	4	zhang	zhang	PROPN
can-1681	379	5	z	z	PROPN
can-1681	379	6	,	,	PUNCT
can-1681	379	7	li	li	PROPN
can-1681	379	8	j	j	PROPN
can-1681	379	9	,	,	PUNCT
can-1681	379	10	et	et	PROPN
can-1681	379	11	al	al	PROPN
can-1681	379	12	.	.	PROPN
can-1681	379	13	diclofenac	diclofenac	NOUN
can-1681	379	14	/	/	SYM
can-1681	379	15	biodegradable	biodegradable	ADJ
can-1681	379	16	polymer	polymer	NOUN
can-1681	379	17	micelles	micelle	NOUN
can-1681	379	18	for	for	ADP
can-1681	379	19	ocular	ocular	ADJ
can-1681	379	20	applications	application	NOUN
can-1681	379	21	.	.	PUNCT
can-1681	380	1	nanoscale	nanoscale	NOUN
can-1681	380	2	2012	2012	NUM
can-1681	380	3	;	;	PUNCT
can-1681	380	4	4(15	4(15	NUM
can-1681	380	5	):	):	PUNCT
can-1681	380	6	4667–4673	4667–4673	NUM
can-1681	380	7	.	.	NOUN
can-1681	380	8	45	45	NUM
can-1681	380	9	.	.	PUNCT
can-1681	381	1	salama	salama	PROPN
can-1681	381	2	ah	ah	INTJ
can-1681	381	3	,	,	PUNCT
can-1681	381	4	shamma	shamma	PROPN
can-1681	381	5	rn	rn	PROPN
can-1681	381	6	.	.	PROPN
can-1681	381	7	tri	tri	ADJ
can-1681	381	8	/	/	SYM
can-1681	381	9	tetra	tetra	NOUN
can-1681	381	10	-	-	PUNCT
can-1681	381	11	block	block	NOUN
can-1681	381	12	co	co	ADJ
can-1681	381	13	-	-	ADJ
can-1681	381	14	polymeric	polymeric	ADJ
can-1681	381	15	nanocarriers	nanocarrier	NOUN
can-1681	381	16	as	as	ADP
can-1681	381	17	a	a	DET
can-1681	381	18	potential	potential	ADJ
can-1681	381	19	ocular	ocular	ADJ
can-1681	381	20	delivery	delivery	NOUN
can-1681	381	21	system	system	NOUN
can-1681	381	22	of	of	ADP
can-1681	381	23	lornoxicam	lornoxicam	NOUN
can-1681	381	24	:	:	PUNCT
can-1681	381	25	in	in	ADP
can-1681	381	26	-	-	PUNCT
can-1681	381	27	vitro	vitro	X
can-1681	381	28	characterization	characterization	NOUN
can-1681	381	29	,	,	PUNCT
can-1681	381	30	and	and	CCONJ
can-1681	381	31	in	in	ADP
can-1681	381	32	-	-	PUNCT
can-1681	381	33	vivo	vivo	NOUN
can-1681	381	34	estimation	estimation	NOUN
can-1681	381	35	of	of	ADP
can-1681	381	36	corneal	corneal	ADJ
can-1681	381	37	permeation	permeation	NOUN
can-1681	381	38	.	.	PUNCT
can-1681	382	1	international	international	ADJ
can-1681	382	2	journal	journal	PROPN
can-1681	382	3	of	of	ADP
can-1681	382	4	pharmaceutics	pharmaceutic	NOUN
can-1681	382	5	2015	2015	NUM
can-1681	382	6	;	;	PUNCT
can-1681	382	7	492(1	492(1	NUM
can-1681	382	8	–	–	PUNCT
can-1681	382	9	2	2	NUM
can-1681	382	10	):	):	PUNCT
can-1681	382	11	28–39	28–39	NUM
can-1681	382	12	.	.	PUNCT
can-1681	383	1	46	46	NUM
can-1681	383	2	.	.	PUNCT
can-1681	384	1	silva	silva	PROPN
can-1681	384	2	-	-	PUNCT
can-1681	384	3	abreu	abreu	PROPN
can-1681	384	4	m	m	PROPN
can-1681	384	5	,	,	PUNCT
can-1681	384	6	calpena	calpena	PROPN
can-1681	384	7	ac	ac	PROPN
can-1681	384	8	,	,	PUNCT
can-1681	384	9	espina	espina	PROPN
can-1681	384	10	m	m	PROPN
can-1681	384	11	,	,	PUNCT
can-1681	384	12	et	et	PROPN
can-1681	384	13	al	al	PROPN
can-1681	384	14	.	.	PUNCT
can-1681	384	15	optimization	optimization	PROPN
can-1681	384	16	,	,	PUNCT
can-1681	384	17	biopharmaceutical	biopharmaceutical	NOUN
can-1681	384	18	profile	profile	NOUN
can-1681	384	19	and	and	CCONJ
can-1681	384	20	therapeutic	therapeutic	ADJ
can-1681	384	21	efficacy	efficacy	NOUN
can-1681	384	22	of	of	ADP
can-1681	384	23	pioglitazone	pioglitazone	NOUN
can-1681	384	24	-	-	PUNCT
can-1681	384	25	loaded	load	VERB
can-1681	384	26	plga	plga	NOUN
can-1681	384	27	-	-	PUNCT
can-1681	384	28	peg	peg	NOUN
can-1681	384	29	nanospheres	nanosphere	NOUN
can-1681	384	30	as	as	ADP
can-1681	384	31	a	a	DET
can-1681	384	32	novel	novel	ADJ
can-1681	384	33	strategy	strategy	NOUN
can-1681	384	34	for	for	ADP
can-1681	384	35	ocular	ocular	ADJ
can-1681	384	36	inflammatory	inflammatory	ADJ
can-1681	384	37	disorders	disorder	NOUN
can-1681	384	38	.	.	PUNCT
can-1681	385	1	pharmaceutical	pharmaceutical	ADJ
can-1681	385	2	research	research	NOUN
can-1681	385	3	2018	2018	NUM
can-1681	385	4	;	;	PUNCT
can-1681	385	5	35(1	35(1	NUM
can-1681	385	6	):	):	PUNCT
can-1681	385	7	11	11	NUM
can-1681	385	8	.	.	X
can-1681	385	9	47	47	NUM
can-1681	385	10	.	.	PUNCT
can-1681	386	1	ustundag	ustundag	NOUN
can-1681	386	2	-	-	PUNCT
can-1681	386	3	okur	okur	NOUN
can-1681	386	4	n	n	CCONJ
can-1681	386	5	,	,	PUNCT
can-1681	386	6	gokce	gokce	ADJ
can-1681	386	7	eh	eh	INTJ
can-1681	386	8	,	,	PUNCT
can-1681	386	9	bozbiik	bozbiik	PROPN
can-1681	386	10	di	di	PROPN
can-1681	386	11	,	,	PUNCT
can-1681	386	12	et	et	PROPN
can-1681	386	13	al	al	PROPN
can-1681	386	14	.	.	PROPN
can-1681	386	15	novel	novel	PROPN
can-1681	386	16	nanostructured	nanostructure	VERB
can-1681	386	17	lipid	lipid	NOUN
can-1681	386	18	carrier	carrier	NOUN
can-1681	386	19	-	-	PUNCT
can-1681	386	20	based	base	VERB
can-1681	386	21	inserts	insert	NOUN
can-1681	386	22	for	for	ADP
can-1681	386	23	controlled	control	VERB
can-1681	386	24	ocular	ocular	ADJ
can-1681	386	25	drug	drug	NOUN
can-1681	386	26	delivery	delivery	NOUN
can-1681	386	27	:	:	PUNCT
can-1681	386	28	evaluation	evaluation	NOUN
can-1681	386	29	of	of	ADP
can-1681	386	30	corneal	corneal	ADJ
can-1681	386	31	bioavailability	bioavailability	NOUN
can-1681	386	32	and	and	CCONJ
can-1681	386	33	treatment	treatment	NOUN
can-1681	386	34	efficacy	efficacy	NOUN
can-1681	386	35	in	in	ADP
can-1681	386	36	bacterial	bacterial	ADJ
can-1681	386	37	keratitis	keratitis	NOUN
can-1681	386	38	.	.	PUNCT
can-1681	387	1	experimental	experimental	ADJ
can-1681	387	2	operation	operation	NOUN
can-1681	387	3	drug	drug	NOUN
can-1681	387	4	delivery	delivery	NOUN
can-1681	387	5	2015	2015	NUM
can-1681	387	6	;	;	PUNCT
can-1681	387	7	12(11	12(11	NUM
can-1681	387	8	):	):	PUNCT
can-1681	387	9	1791–1807	1791–1807	NUM
can-1681	387	10	.	.	PUNCT
can-1681	387	11	48	48	NUM
can-1681	387	12	.	.	PUNCT
can-1681	388	1	ustundag	ustundag	NOUN
can-1681	388	2	-	-	PUNCT
can-1681	388	3	okur	okur	NOUN
can-1681	388	4	n	n	CCONJ
can-1681	388	5	,	,	PUNCT
can-1681	388	6	gokce	gokce	ADJ
can-1681	388	7	eh	eh	INTJ
can-1681	388	8	,	,	PUNCT
can-1681	388	9	bozbiik	bozbiik	PROPN
can-1681	388	10	di	di	PROPN
can-1681	388	11	,	,	PUNCT
can-1681	388	12	et	et	PROPN
can-1681	388	13	al	al	PROPN
can-1681	388	14	.	.	PUNCT
can-1681	388	15	preparation	preparation	NOUN
can-1681	388	16	and	and	CCONJ
can-1681	388	17	in	in	ADP
can-1681	388	18	vitro	vitro	X
can-1681	388	19	-	-	PUNCT
can-1681	388	20	in	in	ADP
can-1681	388	21	vivo	vivo	ADJ
can-1681	388	22	evaluation	evaluation	NOUN
can-1681	388	23	of	of	ADP
can-1681	388	24	chitosan	chitosan	ADJ
can-1681	388	25	oligosaccharide	oligosaccharide	NOUN
can-1681	388	26	lactic	lactic	ADJ
can-1681	388	27	acid	acid	NOUN
can-1681	388	28	modified	modify	VERB
can-1681	388	29	ofloxacin	ofloxacin	NOUN
can-1681	388	30	loaded	load	VERB
can-1681	388	31	ophthalmic	ophthalmic	ADJ
can-1681	388	32	nano	nano	NOUN
can-1681	388	33	structured	structure	VERB
can-1681	388	34	lipid	lipid	NOUN
can-1681	388	35	carriers	carrier	NOUN
can-1681	388	36	modified	modify	VERB
can-1681	388	37	with	with	ADP
can-1681	388	38	chitosan	chitosan	NOUN
can-1681	388	39	oligosaccharide	oligosaccharide	NOUN
can-1681	388	40	lactate	lactate	NOUN
can-1681	388	41	for	for	ADP
can-1681	388	42	the	the	DET
can-1681	388	43	treatment	treatment	NOUN
can-1681	388	44	of	of	ADP
can-1681	388	45	bacterial	bacterial	ADJ
can-1681	388	46	keratitis	keratitis	NOUN
can-1681	388	47	.	.	PUNCT
can-1681	389	1	european	european	PROPN
can-1681	389	2	journal	journal	PROPN
can-1681	389	3	of	of	ADP
can-1681	389	4	pharmaceutical	pharmaceutical	NOUN
can-1681	389	5	science	science	NOUN
can-1681	389	6	2014	2014	NUM
can-1681	389	7	;	;	PUNCT
can-1681	389	8	63	63	NUM
can-1681	389	9	:	:	PUNCT
can-1681	389	10	204–215	204–215	NUM
can-1681	389	11	.	.	NOUN
can-1681	389	12	49	49	NUM
can-1681	389	13	.	.	PUNCT
can-1681	390	1	kaiser	kaiser	PROPN
can-1681	390	2	jm	jm	PROPN
can-1681	390	3	,	,	PUNCT
can-1681	390	4	imai	imai	PROPN
can-1681	390	5	h	h	PROPN
can-1681	390	6	,	,	PUNCT
can-1681	390	7	haakenson	haakenson	PROPN
can-1681	390	8	jk	jk	PROPN
can-1681	390	9	,	,	PUNCT
can-1681	390	10	et	et	PROPN
can-1681	390	11	al	al	PROPN
can-1681	390	12	.	.	PUNCT
can-1681	391	1	nanoliposomal	nanoliposomal	ADJ
can-1681	391	2	minocycline	minocycline	NOUN
can-1681	391	3	for	for	ADP
can-1681	391	4	ocular	ocular	ADJ
can-1681	391	5	drug	drug	NOUN
can-1681	391	6	delivery	delivery	NOUN
can-1681	391	7	.	.	PUNCT
can-1681	392	1	nanomedicine	nanomedicine	NOUN
can-1681	392	2	2013	2013	NUM
can-1681	392	3	;	;	PUNCT
can-1681	392	4	9(1	9(1	NUM
can-1681	392	5	):	):	PUNCT
can-1681	392	6	130–140	130–140	NUM
can-1681	392	7	.	.	PUNCT
can-1681	392	8	50	50	NUM
can-1681	392	9	.	.	PUNCT
can-1681	393	1	campos	campos	PROPN
can-1681	393	2	ej	ej	PROPN
can-1681	393	3	,	,	PUNCT
can-1681	393	4	campos	campos	PROPN
can-1681	393	5	a	a	PRON
can-1681	393	6	,	,	PUNCT
can-1681	393	7	martins	martins	PROPN
can-1681	393	8	j	j	PROPN
can-1681	393	9	,	,	PUNCT
can-1681	393	10	et	et	PROPN
can-1681	393	11	al	al	PROPN
can-1681	393	12	.	.	PUNCT
can-1681	394	1	opening	open	VERB
can-1681	394	2	eyes	eye	NOUN
can-1681	394	3	to	to	ADP
can-1681	394	4	nanomedicine	nanomedicine	NOUN
can-1681	394	5	:	:	PUNCT
can-1681	394	6	where	where	SCONJ
can-1681	394	7	we	we	PRON
can-1681	394	8	are	be	AUX
can-1681	394	9	,	,	PUNCT
can-1681	394	10	challenges	challenge	NOUN
can-1681	394	11	and	and	CCONJ
can-1681	394	12	expectations	expectation	NOUN
can-1681	394	13	on	on	ADP
can-1681	394	14	nanotherapy	nanotherapy	NOUN
can-1681	394	15	for	for	ADP
can-1681	394	16	diabetic	diabetic	ADJ
can-1681	394	17	retinopathy	retinopathy	ADJ
can-1681	394	18	nanocarrier	nanocarrier	NOUN
can-1681	394	19	mediated	mediate	VERB
can-1681	394	20	retinal	retinal	ADJ
can-1681	394	21	drug	drug	NOUN
can-1681	394	22	delivery	delivery	NOUN
can-1681	394	23	:	:	PUNCT
can-1681	394	24	overcoming	overcome	VERB
can-1681	394	25	ocular	ocular	ADJ
can-1681	394	26	barriers	barrier	NOUN
can-1681	394	27	to	to	PART
can-1681	394	28	treat	treat	VERB
can-1681	394	29	posterior	posterior	ADJ
can-1681	394	30	eye	eye	NOUN
can-1681	394	31	diseases	disease	VERB
can-1681	394	32	intraocular	intraocular	ADJ
can-1681	394	33	application	application	NOUN
can-1681	394	34	of	of	ADP
can-1681	394	35	gold	gold	NOUN
can-1681	394	36	nanodisks	nanodisk	NOUN
can-1681	394	37	optically	optically	ADV
can-1681	394	38	tuned	tune	VERB
can-1681	394	39	for	for	ADP
can-1681	394	40	optical	optical	ADJ
can-1681	394	41	coherence	coherence	NOUN
can-1681	394	42	:	:	PUNCT
can-1681	394	43	inhibitory	inhibitory	ADJ
can-1681	394	44	effect	effect	NOUN
can-1681	394	45	on	on	ADP
can-1681	394	46	retinal	retinal	ADJ
can-1681	394	47	neovascularization	neovascularization	NOUN
can-1681	394	48	without	without	ADP
can-1681	394	49	unbearable	unbearable	ADJ
can-1681	394	50	toxicity	toxicity	NOUN
can-1681	394	51	surface	surface	NOUN
can-1681	394	52	plasmon	plasmon	NOUN
can-1681	394	53	-	-	PUNCT
can-1681	394	54	enhanced	enhance	VERB
can-1681	394	55	fluorescence	fluorescence	NOUN
can-1681	394	56	on	on	ADP
can-1681	394	57	au	au	PROPN
can-1681	394	58	nanohole	nanohole	PROPN
can-1681	394	59	array	array	NOUN
can-1681	394	60	for	for	ADP
can-1681	394	61	prostate	prostate	NOUN
can-1681	394	62	-	-	PUNCT
can-1681	394	63	specific	specific	ADJ
can-1681	394	64	antigen	antigen	NOUN
can-1681	394	65	detec	detec	ADJ
can-1681	394	66	77	77	NUM
can-1681	394	67	tion	tion	NOUN
can-1681	394	68	.	.	PUNCT
can-1681	395	1	nanomedicine	nanomedicine	NOUN
can-1681	395	2	2017	2017	NUM
can-1681	395	3	;	;	PUNCT
can-1681	395	4	2017	2017	NUM
can-1681	395	5	:	:	PUNCT
can-1681	395	6	2101–2113	2101–2113	NUM
can-1681	395	7	.	.	PUNCT
can-1681	396	1	51	51	NUM
can-1681	396	2	.	.	PUNCT
can-1681	396	3	honda	honda	PROPN
can-1681	396	4	m	m	PROPN
can-1681	396	5	,	,	PUNCT
can-1681	396	6	asai	asai	PROPN
can-1681	396	7	t	t	PROPN
can-1681	396	8	,	,	PUNCT
can-1681	396	9	oku	oku	PROPN
can-1681	396	10	n	n	CCONJ
can-1681	396	11	,	,	PUNCT
can-1681	396	12	et	et	PROPN
can-1681	396	13	al	al	PROPN
can-1681	396	14	.	.	PUNCT
can-1681	396	15	liposomes	liposome	NOUN
can-1681	396	16	and	and	CCONJ
can-1681	396	17	nanotechnology	nanotechnology	NOUN
can-1681	396	18	in	in	ADP
can-1681	396	19	drug	drug	NOUN
can-1681	396	20	development	development	NOUN
can-1681	396	21	:	:	PUNCT
can-1681	396	22	focus	focus	VERB
can-1681	396	23	on	on	ADP
can-1681	396	24	ocular	ocular	ADJ
can-1681	396	25	targets	target	NOUN
can-1681	396	26	.	.	PUNCT
can-1681	397	1	international	international	ADJ
can-1681	397	2	journal	journal	NOUN
can-1681	397	3	of	of	ADP
can-1681	397	4	nanomedicine	nanomedicine	NOUN
can-1681	397	5	2013	2013	NUM
can-1681	397	6	;	;	PUNCT
can-1681	397	7	8	8	NUM
can-1681	397	8	:	:	PUNCT
can-1681	397	9	495–503	495–503	NUM
can-1681	397	10	.	.	NOUN
can-1681	397	11	52	52	NUM
can-1681	397	12	.	.	PUNCT
can-1681	398	1	wong	wong	PROPN
can-1681	398	2	cw	cw	PROPN
can-1681	398	3	,	,	PUNCT
can-1681	398	4	czarny	czarny	PROPN
can-1681	398	5	b	b	PROPN
can-1681	398	6	,	,	PUNCT
can-1681	398	7	metselaar	metselaar	PROPN
can-1681	398	8	jm	jm	PROPN
can-1681	398	9	,	,	PUNCT
can-1681	398	10	et	et	PROPN
can-1681	398	11	al	al	PROPN
can-1681	398	12	.	.	PUNCT
can-1681	398	13	evaluation	evaluation	NOUN
can-1681	398	14	of	of	ADP
can-1681	398	15	subconjunctival	subconjunctival	ADJ
can-1681	398	16	liposomal	liposomal	PROPN
can-1681	398	17	steroids	steroid	NOUN
can-1681	398	18	for	for	ADP
can-1681	398	19	the	the	DET
can-1681	398	20	treatment	treatment	NOUN
can-1681	398	21	of	of	ADP
can-1681	398	22	experimental	experimental	ADJ
can-1681	398	23	uveitis	uveitis	NOUN
can-1681	398	24	.	.	PUNCT
can-1681	399	1	scientific	scientific	ADJ
can-1681	399	2	reports	report	NOUN
can-1681	399	3	2018	2018	NUM
can-1681	399	4	;	;	PUNCT
can-1681	399	5	8(1	8(1	NOUN
can-1681	399	6	):	):	PUNCT
can-1681	399	7	6604	6604	NUM
can-1681	399	8	.	.	PUNCT
can-1681	400	1	53	53	NUM
can-1681	400	2	.	.	PUNCT
can-1681	401	1	zhang	zhang	PROPN
can-1681	401	2	r	r	PROPN
can-1681	401	3	,	,	PUNCT
can-1681	401	4	qian	qian	PROPN
can-1681	401	5	j	j	PROPN
can-1681	401	6	,	,	PUNCT
can-1681	401	7	li	li	PROPN
can-1681	401	8	x	x	PROPN
can-1681	401	9	,	,	PUNCT
can-1681	401	10	et	et	PROPN
can-1681	401	11	al	al	PROPN
can-1681	401	12	.	.	PROPN
can-1681	401	13	treatment	treatment	NOUN
can-1681	401	14	of	of	ADP
can-1681	401	15	experimental	experimental	ADJ
can-1681	401	16	autoimmune	autoimmune	NOUN
can-1681	401	17	uveoretinitis	uveoretinitis	VERB
can-1681	401	18	with	with	ADP
can-1681	401	19	intravitreal	intravitreal	ADJ
can-1681	401	20	injection	injection	NOUN
can-1681	401	21	of	of	ADP
can-1681	401	22	infliximab	infliximab	NOUN
can-1681	401	23	encapsulated	encapsulate	VERB
can-1681	401	24	in	in	ADP
can-1681	401	25	liposomes	liposome	NOUN
can-1681	401	26	.	.	PUNCT
can-1681	402	1	british	british	ADJ
can-1681	402	2	journal	journal	PROPN
can-1681	402	3	of	of	ADP
can-1681	402	4	ophthalmology	ophthalmology	NOUN
can-1681	402	5	2017	2017	NUM
can-1681	402	6	;	;	PUNCT
can-1681	402	7	101(12	101(12	NUM
can-1681	402	8	):	):	PUNCT
can-1681	402	9	1731–1738	1731–1738	NUM
can-1681	402	10	.	.	PUNCT
can-1681	402	11	54	54	NUM
can-1681	402	12	.	.	PUNCT
can-1681	403	1	tsai	tsai	PROPN
can-1681	403	2	ch	ch	PROPN
can-1681	403	3	,	,	PUNCT
can-1681	403	4	wang	wang	PROPN
can-1681	403	5	py	py	PROPN
can-1681	403	6	,	,	PUNCT
can-1681	403	7	lin	lin	PROPN
can-1681	403	8	ic	ic	PROPN
can-1681	403	9	,	,	PUNCT
can-1681	403	10	et	et	PROPN
can-1681	403	11	al	al	PROPN
can-1681	403	12	.	.	PROPN
can-1681	403	13	ocular	ocular	ADJ
can-1681	403	14	drug	drug	NOUN
can-1681	403	15	delivery	delivery	NOUN
can-1681	403	16	:	:	PUNCT
can-1681	403	17	role	role	NOUN
can-1681	403	18	of	of	ADP
can-1681	403	19	degradable	degradable	ADJ
can-1681	403	20	polymeric	polymeric	ADJ
can-1681	403	21	nanocarriers	nanocarrier	NOUN
can-1681	403	22	for	for	ADP
can-1681	403	23	ophthalmic	ophthalmic	ADJ
can-1681	403	24	application	application	NOUN
can-1681	403	25	.	.	PUNCT
can-1681	404	1	international	international	ADJ
can-1681	404	2	journal	journal	NOUN
can-1681	404	3	of	of	ADP
can-1681	404	4	molecular	molecular	ADJ
can-1681	404	5	science	science	NOUN
can-1681	404	6	2018	2018	NUM
can-1681	404	7	;	;	PUNCT
can-1681	404	8	19(9	19(9	NUM
can-1681	404	9	)	)	PUNCT
can-1681	404	10	.	.	PUNCT
can-1681	405	1	55	55	NUM
can-1681	405	2	.	.	X
can-1681	406	1	alhalafi	alhalafi	PROPN
can-1681	406	2	am	be	AUX
can-1681	406	3	.	.	PUNCT
can-1681	407	1	application	application	NOUN
can-1681	407	2	of	of	ADP
can-1681	407	3	polymers	polymer	NOUN
can-1681	407	4	in	in	ADP
can-1681	407	5	intraocular	intraocular	ADJ
can-1681	407	6	drug	drug	NOUN
can-1681	407	7	delivery	delivery	NOUN
can-1681	407	8	systems	system	NOUN
can-1681	407	9	.	.	PUNCT
can-1681	408	1	oman	oman	PROPN
can-1681	408	2	journal	journal	PROPN
can-1681	408	3	of	of	ADP
can-1681	408	4	ophthalmology	ophthalmology	NOUN
can-1681	408	5	2017	2017	NUM
can-1681	408	6	;	;	PUNCT
can-1681	408	7	10(1	10(1	NUM
can-1681	408	8	):	):	PUNCT
can-1681	408	9	3–8	3–8	NUM
can-1681	408	10	.	.	X
can-1681	409	1	56	56	NUM
can-1681	409	2	.	.	PUNCT
can-1681	409	3	mittal	mittal	PROPN
can-1681	409	4	n	n	CCONJ
can-1681	409	5	,	,	PUNCT
can-1681	409	6	kaur	kaur	PROPN
can-1681	409	7	g.	g.	NOUN
can-1681	409	8	investigations	investigation	NOUN
can-1681	409	9	on	on	ADP
can-1681	409	10	polymeric	polymeric	ADJ
can-1681	409	11	nanoparticles	nanoparticle	NOUN
can-1681	409	12	for	for	ADP
can-1681	409	13	ocular	ocular	ADJ
can-1681	409	14	delivery	delivery	NOUN
can-1681	409	15	.	.	PUNCT
can-1681	410	1	advances	advance	NOUN
can-1681	410	2	in	in	ADP
can-1681	410	3	polymer	polymer	NOUN
can-1681	410	4	technology	technology	NOUN
can-1681	410	5	2019	2019	NUM
can-1681	410	6	;	;	PUNCT
can-1681	410	7	2019	2019	NUM
can-1681	410	8	:	:	PUNCT
can-1681	410	9	1316249	1316249	NUM
can-1681	410	10	.	.	PUNCT
can-1681	411	1	57	57	NUM
can-1681	411	2	.	.	PUNCT
can-1681	412	1	yavuz	yavuz	PROPN
can-1681	412	2	b	b	PROPN
can-1681	412	3	,	,	PUNCT
can-1681	412	4	pehlivan	pehlivan	PROPN
can-1681	412	5	sb	sb	PROPN
can-1681	412	6	,	,	PUNCT
can-1681	412	7	unlu	unlu	ADJ
can-1681	412	8	n.	n.	NOUN
can-1681	412	9	dendrimeric	dendrimeric	ADJ
can-1681	412	10	systems	system	NOUN
can-1681	412	11	and	and	CCONJ
can-1681	412	12	their	their	PRON
can-1681	412	13	applications	application	NOUN
can-1681	412	14	in	in	ADP
can-1681	412	15	ocular	ocular	ADJ
can-1681	412	16	drug	drug	NOUN
can-1681	412	17	delivery	delivery	NOUN
can-1681	412	18	.	.	PUNCT
can-1681	413	1	scientific	scientific	ADJ
can-1681	413	2	world	world	PROPN
can-1681	413	3	journal	journal	PROPN
can-1681	413	4	2013	2013	NUM
can-1681	413	5	;	;	PUNCT
can-1681	413	6	2013	2013	NUM
can-1681	413	7	:	:	PUNCT
can-1681	413	8	732340	732340	NUM
can-1681	413	9	.	.	PUNCT
can-1681	414	1	58	58	NUM
can-1681	414	2	.	.	PUNCT
can-1681	415	1	kambhampati	kambhampati	PROPN
can-1681	415	2	sp	sp	PROPN
can-1681	415	3	,	,	PUNCT
can-1681	415	4	kannan	kannan	PROPN
can-1681	415	5	rm	rm	PROPN
can-1681	415	6	,	,	PUNCT
can-1681	415	7	zarbin	zarbin	PROPN
can-1681	415	8	ma	ma	PROPN
can-1681	415	9	,	,	PUNCT
can-1681	415	10	et	et	PROPN
can-1681	415	11	al	al	PROPN
can-1681	415	12	.	.	PROPN
can-1681	416	1	dendrimer	dendrimer	PROPN
can-1681	416	2	nanoparticles	nanoparticle	NOUN
can-1681	416	3	for	for	ADP
can-1681	416	4	ocular	ocular	ADJ
can-1681	416	5	drug	drug	NOUN
can-1681	416	6	delivery	delivery	NOUN
can-1681	416	7	nanomedicine	nanomedicine	NOUN
can-1681	416	8	for	for	ADP
can-1681	416	9	the	the	DET
can-1681	416	10	treatment	treatment	NOUN
can-1681	416	11	of	of	ADP
can-1681	416	12	retinal	retinal	ADJ
can-1681	416	13	and	and	CCONJ
can-1681	416	14	optic	optic	ADJ
can-1681	416	15	nerve	nerve	NOUN
can-1681	416	16	diseases	disease	NOUN
can-1681	416	17	low	low	ADJ
can-1681	416	18	molecular	molecular	ADJ
can-1681	416	19	weight	weight	NOUN
can-1681	416	20	oligochitosans	oligochitosan	NOUN
can-1681	416	21	for	for	ADP
can-1681	416	22	non	non	ADJ
can-1681	416	23	-	-	ADJ
can-1681	416	24	viral	viral	ADJ
can-1681	416	25	retinal	retinal	ADJ
can-1681	416	26	gene	gene	NOUN
can-1681	416	27	therapy	therapy	NOUN
can-1681	416	28	downregulation	downregulation	NOUN
can-1681	416	29	of	of	ADP
can-1681	416	30	vegf	vegf	PROPN
can-1681	416	31	mrna	mrna	PROPN
can-1681	416	32	expression	expression	NOUN
can-1681	416	33	by	by	ADP
can-1681	416	34	triamcinolone	triamcinolone	PROPN
can-1681	416	35	acetonide	acetonide	PROPN
can-1681	416	36	acetate	acetate	NOUN
can-1681	416	37	-	-	PUNCT
can-1681	416	38	loaded	load	VERB
can-1681	416	39	chitosan	chitosan	ADJ
can-1681	416	40	derivative	derivative	ADJ
can-1681	416	41	nanoparticles	nanoparticle	NOUN
can-1681	416	42	in	in	ADP
can-1681	416	43	human	human	ADJ
can-1681	416	44	retinal	retinal	ADJ
can-1681	416	45	pigment	pigment	ADJ
can-1681	416	46	epithelial	epithelial	ADJ
can-1681	416	47	cells	cell	NOUN
can-1681	416	48	.	.	PUNCT
can-1681	417	1	journal	journal	NOUN
can-1681	417	2	of	of	ADP
can-1681	417	3	ocular	ocular	ADJ
can-1681	417	4	pharmacology	pharmacology	NOUN
can-1681	417	5	and	and	CCONJ
can-1681	417	6	therapeutics	therapeutic	NOUN
can-1681	417	7	2013	2013	NUM
can-1681	417	8	;	;	PUNCT
can-1681	417	9	29(2	29(2	NUM
can-1681	417	10	):	):	PUNCT
can-1681	417	11	151–165	151–165	NUM
can-1681	417	12	.	.	PUNCT
can-1681	418	1	59	59	NUM
can-1681	418	2	.	.	PUNCT
can-1681	418	3	iezzi	iezzi	PROPN
can-1681	418	4	r	r	NOUN
can-1681	418	5	,	,	PUNCT
can-1681	418	6	guru	guru	NOUN
can-1681	418	7	br	br	PROPN
can-1681	418	8	,	,	PUNCT
can-1681	418	9	glibina	glibina	PROPN
can-1681	418	10	iv	iv	NUM
can-1681	418	11	,	,	PUNCT
can-1681	418	12	et	et	PROPN
can-1681	418	13	al	al	PROPN
can-1681	418	14	.	.	PUNCT
can-1681	418	15	dendrimer	dendrimer	PROPN
can-1681	418	16	-	-	PUNCT
can-1681	418	17	based	base	VERB
can-1681	418	18	targeted	target	VERB
can-1681	418	19	intravitreal	intravitreal	NOUN
can-1681	418	20	therapy	therapy	NOUN
can-1681	418	21	for	for	ADP
can-1681	418	22	sustained	sustained	ADJ
can-1681	418	23	attenuation	attenuation	NOUN
can-1681	418	24	of	of	ADP
can-1681	418	25	neuroinflammation	neuroinflammation	NOUN
can-1681	418	26	in	in	ADP
can-1681	418	27	retinal	retinal	ADJ
can-1681	418	28	degeneration	degeneration	NOUN
can-1681	418	29	.	.	PUNCT
can-1681	419	1	biomaterials	biomaterial	NOUN
can-1681	419	2	2012	2012	NUM
can-1681	419	3	;	;	PUNCT
can-1681	419	4	33(3	33(3	NUM
can-1681	419	5	):	):	PUNCT
can-1681	419	6	979–988	979–988	NUM
can-1681	419	7	.	.	PUNCT
can-1681	419	8	60	60	NUM
can-1681	419	9	.	.	PUNCT
can-1681	420	1	kang	kang	PROPN
can-1681	420	2	sj	sj	PROPN
can-1681	420	3	,	,	PUNCT
can-1681	420	4	durairaj	durairaj	VERB
can-1681	420	5	c	c	NOUN
can-1681	420	6	,	,	PUNCT
can-1681	420	7	kompella	kompella	PROPN
can-1681	420	8	ub	ub	PROPN
can-1681	420	9	,	,	PUNCT
can-1681	420	10	et	et	PROPN
can-1681	420	11	al	al	PROPN
can-1681	420	12	.	.	PROPN
can-1681	421	1	subconjunctival	subconjunctival	PROPN
can-1681	421	2	nanoparticle	nanoparticle	NOUN
can-1681	421	3	carboplatin	carboplatin	NOUN
can-1681	421	4	in	in	ADP
can-1681	421	5	the	the	DET
can-1681	421	6	treatment	treatment	NOUN
can-1681	421	7	of	of	ADP
can-1681	421	8	murine	murine	ADJ
can-1681	421	9	retinoblastoma	retinoblastoma	NOUN
can-1681	421	10	.	.	PUNCT
can-1681	422	1	arch	arch	ADJ
can-1681	422	2	ophthalmol	ophthalmol	PROPN
can-1681	422	3	2009	2009	NUM
can-1681	422	4	;	;	PUNCT
can-1681	422	5	127(8	127(8	NUM
can-1681	422	6	):	):	PUNCT
can-1681	422	7	1043–1047	1043–1047	NUM
can-1681	422	8	.	.	NOUN
can-1681	422	9	61	61	NUM
can-1681	422	10	.	.	PUNCT
can-1681	423	1	mandal	mandal	PROPN
can-1681	423	2	a	a	PRON
can-1681	423	3	,	,	PUNCT
can-1681	423	4	goth	goth	ADJ
can-1681	423	5	v	v	NOUN
can-1681	423	6	,	,	PUNCT
can-1681	423	7	pal	pal	NOUN
can-1681	423	8	d	d	NOUN
can-1681	423	9	,	,	PUNCT
can-1681	423	10	et	et	PROPN
can-1681	423	11	al	al	PROPN
can-1681	423	12	.	.	PROPN
can-1681	424	1	ocular	ocular	ADJ
can-1681	424	2	pharmacokinetics	pharmacokinetic	NOUN
can-1681	424	3	of	of	ADP
can-1681	424	4	a	a	DET
can-1681	424	5	topical	topical	ADJ
can-1681	424	6	ophthalmic	ophthalmic	ADJ
can-1681	424	7	nanomicellar	nanomicellar	ADJ
can-1681	424	8	solution	solution	NOUN
can-1681	424	9	of	of	ADP
can-1681	424	10	cyclosporine	cyclosporine	PROPN
can-1681	424	11	(	(	PUNCT
can-1681	424	12	cequa	cequa	NOUN
can-1681	424	13	(	(	PUNCT
can-1681	424	14	r	r	NOUN
can-1681	424	15	)	)	PUNCT
can-1681	424	16	)	)	PUNCT
can-1681	424	17	for	for	ADP
can-1681	424	18	dry	dry	ADJ
can-1681	424	19	eye	eye	NOUN
can-1681	424	20	disease	disease	NOUN
can-1681	424	21	.	.	PUNCT
can-1681	425	1	pharmaceutical	pharmaceutical	NOUN
can-1681	425	2	research	research	NOUN
can-1681	425	3	2019	2019	NUM
can-1681	425	4	;	;	PUNCT
can-1681	425	5	36(2	36(2	NUM
can-1681	425	6	):	):	PUNCT
can-1681	425	7	36	36	NUM
can-1681	425	8	.	.	NUM
can-1681	425	9	62	62	NUM
can-1681	425	10	.	.	PUNCT
can-1681	426	1	perini	perini	PROPN
can-1681	426	2	g	g	PROPN
can-1681	426	3	,	,	PUNCT
can-1681	426	4	saettone	saettone	PROPN
can-1681	426	5	mf	mf	NOUN
can-1681	426	6	,	,	PUNCT
can-1681	426	7	carafa	carafa	PROPN
can-1681	426	8	m	m	PROPN
can-1681	426	9	,	,	PUNCT
can-1681	426	10	et	et	PROPN
can-1681	426	11	al	al	PROPN
can-1681	426	12	.	.	PROPN
can-1681	426	13	niosomes	niosome	NOUN
can-1681	426	14	as	as	ADP
can-1681	426	15	carriers	carrier	NOUN
can-1681	426	16	for	for	ADP
can-1681	426	17	ophthalmic	ophthalmic	ADJ
can-1681	426	18	drugs	drug	NOUN
can-1681	426	19	:	:	PUNCT
can-1681	426	20	in	in	ADP
can-1681	426	21	vitro	vitro	VERB
can-1681	426	22	/	/	SYM
can-1681	426	23	in	in	ADP
can-1681	426	24	vivo	vivo	ADJ
can-1681	426	25	evaluation	evaluation	NOUN
can-1681	426	26	.	.	PUNCT
can-1681	427	1	bolettino	bolettino	NOUN
can-1681	427	2	chimico	chimico	NOUN
can-1681	427	3	farmaceutico	farmaceutico	NOUN
can-1681	427	4	1996	1996	NUM
can-1681	427	5	;	;	PUNCT
can-1681	427	6	135(2	135(2	NUM
can-1681	427	7	):	):	PUNCT
can-1681	427	8	145–146	145–146	NUM
can-1681	427	9	.	.	PUNCT
can-1681	428	1	63	63	NUM
can-1681	428	2	.	.	PUNCT
can-1681	429	1	abdelkad	abdelkad	PROPN
can-1681	429	2	h	h	PROPN
can-1681	429	3	,	,	PUNCT
can-1681	429	4	alani	alani	PROPN
can-1681	429	5	aw	aw	PROPN
can-1681	429	6	,	,	PUNCT
can-1681	429	7	alani	alani	PROPN
can-1681	429	8	rg	rg	PROPN
can-1681	429	9	.	.	PUNCT
can-1681	430	1	recent	recent	ADJ
can-1681	430	2	advances	advance	NOUN
can-1681	430	3	in	in	ADP
can-1681	430	4	non	non	ADJ
can-1681	430	5	-	-	ADJ
can-1681	430	6	ionic	ionic	ADJ
can-1681	430	7	surfactant	surfactant	ADJ
can-1681	430	8	vesicles	vesicle	NOUN
can-1681	430	9	(	(	PUNCT
can-1681	430	10	niosomes	niosome	NOUN
can-1681	430	11	):	):	PUNCT
can-1681	430	12	self	self	NOUN
can-1681	430	13	-	-	PUNCT
can-1681	430	14	assembly	assembly	NOUN
can-1681	430	15	,	,	PUNCT
can-1681	430	16	fabrication	fabrication	NOUN
can-1681	430	17	,	,	PUNCT
can-1681	430	18	characterization	characterization	NOUN
can-1681	430	19	,	,	PUNCT
can-1681	430	20	drug	drug	NOUN
can-1681	430	21	delivery	delivery	NOUN
can-1681	430	22	application	application	NOUN
can-1681	430	23	and	and	CCONJ
can-1681	430	24	limitation	limitation	NOUN
can-1681	430	25	.	.	PUNCT
can-1681	431	1	drug	drug	NOUN
can-1681	431	2	delivery	delivery	NOUN
can-1681	431	3	.	.	PUNCT
can-1681	432	1	2014	2014	NUM
can-1681	432	2	;	;	PUNCT
can-1681	432	3	21(2	21(2	NUM
can-1681	432	4	):	):	PUNCT
can-1681	432	5	87–100	87–100	PROPN
can-1681	432	6	.	.	PROPN
can-1681	433	1	64	64	NUM
can-1681	433	2	.	.	PUNCT
can-1681	434	1	yadav	yadav	PROPN
can-1681	434	2	ks	ks	PROPN
can-1681	434	3	,	,	PUNCT
can-1681	434	4	rajpurohit	rajpurohit	VERB
can-1681	434	5	r	r	NOUN
can-1681	434	6	,	,	PUNCT
can-1681	434	7	sharma	sharma	PROPN
can-1681	434	8	s.	s.	PROPN
can-1681	434	9	glaucoma	glaucoma	PROPN
can-1681	434	10	:	:	PUNCT
can-1681	434	11	current	current	ADJ
can-1681	434	12	treatment	treatment	NOUN
can-1681	434	13	and	and	CCONJ
can-1681	434	14	impact	impact	NOUN
can-1681	434	15	of	of	ADP
can-1681	434	16	advanced	advanced	ADJ
can-1681	434	17	drug	drug	NOUN
can-1681	434	18	delivery	delivery	NOUN
can-1681	434	19	systems	system	NOUN
can-1681	434	20	.	.	PUNCT
can-1681	435	1	life	life	NOUN
can-1681	435	2	sciences	science	NOUN
can-1681	435	3	2019	2019	NUM
can-1681	435	4	;	;	PUNCT
can-1681	435	5	221	221	NUM
can-1681	435	6	:	:	PUNCT
can-1681	436	1	362–376	362–376	NUM
can-1681	436	2	.	.	PUNCT
can-1681	437	1	65	65	NUM
can-1681	437	2	.	.	PUNCT
can-1681	438	1	khalil	khalil	PROPN
can-1681	438	2	rm	rm	PROPN
can-1681	438	3	,	,	PUNCT
can-1681	438	4	abdulbari	abdulbari	PROPN
can-1681	438	5	ga	ga	PROPN
can-1681	438	6	,	,	PUNCT
can-1681	438	7	basham	basham	PROPN
can-1681	438	8	m	m	PROPN
can-1681	438	9	,	,	PUNCT
can-1681	438	10	et	et	PROPN
can-1681	438	11	al	al	PROPN
can-1681	438	12	.	.	PROPN
can-1681	438	13	design	design	NOUN
can-1681	438	14	and	and	CCONJ
can-1681	438	15	evaluation	evaluation	NOUN
can-1681	438	16	of	of	ADP
can-1681	438	17	proniosomes	proniosome	NOUN
can-1681	438	18	as	as	ADP
can-1681	438	19	a	a	DET
can-1681	438	20	carrier	carrier	NOUN
can-1681	438	21	for	for	ADP
can-1681	438	22	ocular	ocular	ADJ
can-1681	438	23	delivery	delivery	NOUN
can-1681	438	24	of	of	ADP
can-1681	438	25	lomefoxacin	lomefoxacin	PROPN
can-1681	438	26	hci	hci	PROPN
can-1681	438	27	.	.	PUNCT
can-1681	438	28	journal	journal	PROPN
can-1681	438	29	of	of	ADP
can-1681	438	30	liposome	liposome	PROPN
can-1681	438	31	research	research	NOUN
can-1681	438	32	2017	2017	NUM
can-1681	438	33	;	;	PUNCT
can-1681	438	34	27(2	27(2	NUM
can-1681	438	35	):	):	PUNCT
can-1681	438	36	118–129	118–129	NUM
can-1681	438	37	.	.	PUNCT
can-1681	439	1	66	66	NUM
can-1681	439	2	.	.	PUNCT
can-1681	439	3	battaglia	battaglia	PROPN
can-1681	439	4	l	l	PROPN
can-1681	439	5	,	,	PUNCT
can-1681	439	6	serpe	serpe	PROPN
can-1681	439	7	l	l	PROPN
can-1681	439	8	,	,	PUNCT
can-1681	439	9	foglietta	foglietta	PROPN
can-1681	439	10	f	f	NOUN
can-1681	439	11	,	,	PUNCT
can-1681	439	12	et	et	PROPN
can-1681	439	13	al	al	PROPN
can-1681	439	14	.	.	PUNCT
can-1681	439	15	application	application	NOUN
can-1681	439	16	of	of	ADP
can-1681	439	17	lipid	lipid	ADJ
can-1681	439	18	nanoparticles	nanoparticle	NOUN
can-1681	439	19	to	to	ADP
can-1681	439	20	ocular	ocular	ADJ
can-1681	439	21	drug	drug	NOUN
can-1681	439	22	delivery	delivery	NOUN
can-1681	439	23	.	.	PUNCT
can-1681	440	1	expert	expert	ADJ
can-1681	440	2	opinion	opinion	NOUN
can-1681	440	3	on	on	ADP
can-1681	440	4	drug	drug	NOUN
can-1681	440	5	delivery	delivery	NOUN
can-1681	440	6	2016	2016	NUM
can-1681	440	7	;	;	PUNCT
can-1681	440	8	13(12	13(12	NUM
can-1681	440	9	):	):	PUNCT
can-1681	440	10	1743	1743	NUM
can-1681	440	11	–	–	PUNCT
can-1681	440	12	1757	1757	NUM
can-1681	440	13	.	.	PUNCT
can-1681	441	1	67	67	NUM
can-1681	441	2	.	.	PUNCT
can-1681	442	1	gan	gan	PROPN
can-1681	442	2	l	l	PROPN
can-1681	442	3	,	,	PUNCT
can-1681	442	4	wang	wang	PROPN
can-1681	442	5	j	j	PROPN
can-1681	442	6	,	,	PUNCT
can-1681	442	7	jiang	jiang	PROPN
can-1681	442	8	m	m	PROPN
can-1681	442	9	,	,	PUNCT
can-1681	442	10	et	et	PROPN
can-1681	442	11	al	al	PROPN
can-1681	442	12	.	.	PUNCT
can-1681	443	1	recent	recent	ADJ
can-1681	443	2	advances	advance	NOUN
can-1681	443	3	in	in	ADP
can-1681	443	4	topical	topical	ADJ
can-1681	443	5	ophthalmic	ophthalmic	ADJ
can-1681	443	6	drug	drug	NOUN
can-1681	443	7	delivery	delivery	NOUN
can-1681	443	8	with	with	ADP
can-1681	443	9	lipid	lipid	NOUN
can-1681	443	10	-	-	PUNCT
can-1681	443	11	based	base	VERB
can-1681	443	12	nanocarriers	nanocarrier	NOUN
can-1681	443	13	.	.	PUNCT
can-1681	444	1	drug	drug	NOUN
can-1681	444	2	discovery	discovery	PROPN
can-1681	444	3	today	today	NOUN
can-1681	444	4	2013	2013	NUM
can-1681	444	5	;	;	PUNCT
can-1681	444	6	18(5–6	18(5–6	NUM
can-1681	444	7	):	):	PUNCT
can-1681	444	8	290–297	290–297	NUM
can-1681	444	9	.	.	PUNCT
can-1681	445	1	68	68	NUM
can-1681	445	2	.	.	PUNCT
can-1681	446	1	han	han	PROPN
can-1681	446	2	s	s	PROPN
can-1681	446	3	,	,	PUNCT
can-1681	446	4	shen	shen	PROPN
can-1681	446	5	jq	jq	PROPN
can-1681	446	6	,	,	PUNCT
can-1681	446	7	gan	gan	PROPN
can-1681	446	8	y	y	PROPN
can-1681	446	9	,	,	PUNCT
can-1681	446	10	et	et	PROPN
can-1681	446	11	al	al	PROPN
can-1681	446	12	.	.	PROPN
can-1681	446	13	novel	novel	PROPN
can-1681	446	14	vehicle	vehicle	NOUN
can-1681	446	15	based	base	VERB
can-1681	446	16	on	on	ADP
can-1681	446	17	cubosomes	cubosome	NOUN
can-1681	446	18	for	for	ADP
can-1681	446	19	ophthalmic	ophthalmic	ADJ
can-1681	446	20	delivery	delivery	NOUN
can-1681	446	21	of	of	ADP
can-1681	446	22	flurbiprofen	flurbiprofen	NOUN
can-1681	446	23	with	with	ADP
can-1681	446	24	low	low	ADJ
can-1681	446	25	irritancy	irritancy	NOUN
can-1681	446	26	and	and	CCONJ
can-1681	446	27	high	high	ADJ
can-1681	446	28	bioavailability	bioavailability	NOUN
can-1681	446	29	.	.	PUNCT
can-1681	447	1	acta	acta	PROPN
can-1681	447	2	pharmacologica	pharmacologica	PROPN
can-1681	447	3	sinica	sinica	PROPN
can-1681	447	4	2010	2010	NUM
can-1681	447	5	;	;	PUNCT
can-1681	447	6	31(8	31(8	NUM
can-1681	447	7	):	):	PUNCT
can-1681	447	8	990–998	990–998	NUM
can-1681	447	9	.	.	PUNCT
can-1681	448	1	69	69	NUM
can-1681	448	2	.	.	PUNCT
can-1681	449	1	huang	huang	PROPN
can-1681	449	2	j	j	PROPN
can-1681	449	3	,	,	PUNCT
can-1681	449	4	peng	peng	PROPN
can-1681	449	5	t	t	PROPN
can-1681	449	6	,	,	PUNCT
can-1681	449	7	li	li	PROPN
can-1681	449	8	y	y	PROPN
can-1681	449	9	,	,	PUNCT
can-1681	449	10	et	et	PROPN
can-1681	449	11	al	al	PROPN
can-1681	449	12	.	.	PROPN
can-1681	449	13	ocular	ocular	ADJ
can-1681	449	14	cubosome	cubosome	NOUN
can-1681	449	15	drug	drug	NOUN
can-1681	449	16	delivery	delivery	NOUN
can-1681	449	17	system	system	NOUN
can-1681	449	18	for	for	ADP
can-1681	449	19	timolol	timolol	NOUN
can-1681	449	20	maleate	maleate	NOUN
can-1681	449	21	:	:	PUNCT
can-1681	449	22	preparation	preparation	NOUN
can-1681	449	23	,	,	PUNCT
can-1681	449	24	characterization	characterization	NOUN
can-1681	449	25	,	,	PUNCT
can-1681	449	26	cytotoxicity	cytotoxicity	NOUN
can-1681	449	27	,	,	PUNCT
can-1681	449	28	ex	ex	NOUN
can-1681	449	29	vivo	vivo	NOUN
can-1681	449	30	,	,	PUNCT
can-1681	449	31	and	and	CCONJ
can-1681	449	32	in	in	ADP
can-1681	449	33	vivo	vivo	ADJ
can-1681	449	34	evaluation	evaluation	NOUN
can-1681	449	35	.	.	PUNCT
can-1681	450	1	aaps	aap	NOUN
can-1681	450	2	pharmscitech	pharmscitech	VERB
can-1681	450	3	2017	2017	NUM
can-1681	450	4	;	;	PUNCT
can-1681	450	5	18(8	18(8	NUM
can-1681	450	6	):	):	PUNCT
can-1681	450	7	2919–2926	2919–2926	NOUN
can-1681	450	8	.	.	PUNCT
can-1681	451	1	70	70	NUM
can-1681	451	2	.	.	PUNCT
can-1681	452	1	hartnett	hartnett	PROPN
can-1681	452	2	te	te	PROPN
can-1681	452	3	,	,	PUNCT
can-1681	452	4	o’connor	o’connor	ADV
can-1681	452	5	aj	aj	PROPN
can-1681	452	6	,	,	PUNCT
can-1681	452	7	ladewig	ladewig	PROPN
can-1681	452	8	k.	k.	PROPN
can-1681	452	9	cubosomes	cubosomes	PROPN
can-1681	452	10	and	and	CCONJ
can-1681	452	11	other	other	ADJ
can-1681	452	12	potential	potential	ADJ
can-1681	452	13	ocular	ocular	ADJ
can-1681	452	14	drug	drug	NOUN
can-1681	452	15	delivery	delivery	NOUN
can-1681	452	16	vehicles	vehicle	NOUN
can-1681	452	17	for	for	ADP
can-1681	452	18	macromolecular	macromolecular	ADJ
can-1681	452	19	therapeutics	therapeutic	NOUN
can-1681	452	20	.	.	PUNCT
can-1681	453	1	expert	expert	ADJ
can-1681	453	2	opinion	opinion	NOUN
can-1681	453	3	on	on	ADP
can-1681	453	4	drug	drug	NOUN
can-1681	453	5	delivery	delivery	NOUN
can-1681	453	6	2015	2015	NUM
can-1681	453	7	;	;	PUNCT
can-1681	453	8	12(9	12(9	NUM
can-1681	453	9	):	):	PUNCT
can-1681	453	10	1513–1526	1513–1526	NUM
can-1681	453	11	.	.	PUNCT
can-1681	454	1	71	71	NUM
can-1681	454	2	.	.	PUNCT
can-1681	455	1	gan	gan	PROPN
can-1681	455	2	l	l	PROPN
can-1681	455	3	,	,	PUNCT
can-1681	455	4	han	han	PROPN
can-1681	455	5	s	s	PROPN
can-1681	455	6	,	,	PUNCT
can-1681	455	7	shen	shen	PROPN
can-1681	455	8	j	j	PROPN
can-1681	455	9	,	,	PUNCT
can-1681	455	10	et	et	PROPN
can-1681	455	11	al	al	PROPN
can-1681	455	12	.	.	PROPN
can-1681	455	13	self	self	NOUN
can-1681	455	14	-	-	PUNCT
can-1681	455	15	assembled	assemble	VERB
can-1681	455	16	liquid	liquid	ADJ
can-1681	455	17	crystalline	crystalline	NOUN
can-1681	455	18	nanoparticles	nanoparticle	NOUN
can-1681	455	19	as	as	ADP
can-1681	455	20	a	a	DET
can-1681	455	21	novel	novel	ADJ
can-1681	455	22	ophthalmic	ophthalmic	ADJ
can-1681	455	23	delivery	delivery	NOUN
can-1681	455	24	system	system	NOUN
can-1681	455	25	for	for	ADP
can-1681	455	26	dexamethasone	dexamethasone	NOUN
can-1681	455	27	:	:	PUNCT
can-1681	455	28	improving	improve	VERB
can-1681	455	29	preocular	preocular	ADJ
can-1681	455	30	retention	retention	NOUN
can-1681	455	31	and	and	CCONJ
can-1681	455	32	ocular	ocular	ADJ
can-1681	455	33	bioavailability	bioavailability	NOUN
can-1681	455	34	.	.	PUNCT
can-1681	456	1	international	international	ADJ
can-1681	456	2	journal	journal	PROPN
can-1681	456	3	of	of	ADP
can-1681	456	4	pharmaceutics	pharmaceutic	NOUN
can-1681	456	5	2010	2010	NUM
can-1681	456	6	;	;	PUNCT
can-1681	456	7	396(1–2	396(1–2	NUM
can-1681	456	8	):	):	PUNCT
can-1681	456	9	179–187	179–187	NUM
can-1681	456	10	.	.	PUNCT
can-1681	457	1	72	72	NUM
can-1681	457	2	.	.	X
can-1681	457	3	cooper	cooper	PROPN
can-1681	457	4	rc	rc	PROPN
can-1681	457	5	,	,	PUNCT
can-1681	457	6	yang	yang	PROPN
can-1681	457	7	h.	h.	PROPN
can-1681	457	8	hydrogel	hydrogel	PROPN
can-1681	457	9	-	-	PUNCT
can-1681	457	10	based	base	VERB
can-1681	457	11	ocular	ocular	ADJ
can-1681	457	12	drug	drug	NOUN
can-1681	457	13	delivery	delivery	NOUN
can-1681	457	14	system	system	NOUN
can-1681	457	15	:	:	PUNCT
can-1681	457	16	emerging	emerge	VERB
can-1681	457	17	fabrication	fabrication	NOUN
can-1681	457	18	strategies	strategy	NOUN
can-1681	457	19	,	,	PUNCT
can-1681	457	20	applications	application	NOUN
can-1681	457	21	,	,	PUNCT
can-1681	457	22	and	and	CCONJ
can-1681	457	23	bench	bench	NOUN
can-1681	457	24	-	-	PUNCT
can-1681	457	25	to	to	ADP
can-1681	457	26	-	-	PUNCT
can-1681	457	27	bedside	bedside	NOUN
can-1681	457	28	manufacturing	manufacturing	NOUN
can-1681	457	29	considerations	consideration	NOUN
can-1681	457	30	.	.	PUNCT
can-1681	458	1	journal	journal	PROPN
can-1681	458	2	of	of	ADP
can-1681	458	3	control	control	NOUN
can-1681	458	4	release	release	NOUN
can-1681	458	5	2019	2019	NUM
can-1681	458	6	;	;	PUNCT
can-1681	458	7	306	306	NUM
can-1681	458	8	:	:	PUNCT
can-1681	458	9	29–39	29–39	NUM
can-1681	458	10	.	.	PUNCT
can-1681	459	1	73	73	NUM
can-1681	459	2	.	.	PUNCT
can-1681	460	1	kirchhoff	kirchhoff	PROPN
can-1681	460	2	s	s	PART
can-1681	460	3	,	,	PUNCT
can-1681	460	4	godfrey	godfrey	PROPN
can-1681	460	5	am	be	AUX
can-1681	460	6	,	,	PUNCT
can-1681	460	7	brandell	brandell	PROPN
can-1681	460	8	fp	fp	NOUN
can-1681	460	9	.	.	PROPN
can-1681	460	10	hydrogels	hydrogel	NOUN
can-1681	460	11	in	in	ADP
can-1681	460	12	ophthalmic	ophthalmic	ADJ
can-1681	460	13	applications	application	NOUN
can-1681	460	14	.	.	PUNCT
can-1681	461	1	european	european	ADJ
can-1681	461	2	journal	journal	PROPN
can-1681	461	3	of	of	ADP
can-1681	461	4	pharmaceutical	pharmaceutical	ADJ
can-1681	461	5	biopharmaceutical	biopharmaceutical	NOUN
can-1681	461	6	2015	2015	NUM
can-1681	461	7	;	;	PUNCT
can-1681	461	8	95(pt	95(pt	NUM
can-1681	461	9	b	b	NUM
can-1681	461	10	):	):	PUNCT
can-1681	461	11	227–238	227–238	NUM
can-1681	461	12	.	.	PUNCT
can-1681	462	1	74	74	NUM
can-1681	462	2	.	.	PUNCT
can-1681	462	3	jung	jung	PROPN
can-1681	462	4	hj	hj	PROPN
can-1681	462	5	,	,	PUNCT
can-1681	462	6	abou	abou	PROPN
can-1681	462	7	-	-	PUNCT
can-1681	462	8	jaoude	jaoude	PROPN
can-1681	462	9	m	m	PROPN
can-1681	462	10	,	,	PUNCT
can-1681	462	11	carbia	carbia	NOUN
can-1681	462	12	be	be	VERB
can-1681	462	13	,	,	PUNCT
can-1681	462	14	et	et	PROPN
can-1681	462	15	al	al	PROPN
can-1681	462	16	.	.	PUNCT
can-1681	462	17	glaucoma	glaucoma	NOUN
can-1681	462	18	therapy	therapy	NOUN
can-1681	462	19	by	by	ADP
can-1681	462	20	extended	extended	ADJ
can-1681	462	21	release	release	NOUN
can-1681	462	22	of	of	ADP
can-1681	462	23	timolol	timolol	NOUN
can-1681	462	24	from	from	ADP
can-1681	462	25	nanoparticle	nanoparticle	NOUN
can-1681	462	26	loaded	load	VERB
can-1681	462	27	silicone	silicone	NOUN
can-1681	462	28	-	-	PUNCT
can-1681	462	29	hydrogel	hydrogel	NOUN
can-1681	462	30	contact	contact	NOUN
can-1681	462	31	lenses	lense	NOUN
can-1681	462	32	.	.	PUNCT
can-1681	463	1	journal	journal	PROPN
can-1681	463	2	of	of	ADP
can-1681	463	3	control	control	PROPN
can-1681	463	4	release	release	NOUN
can-1681	463	5	2013	2013	NUM
can-1681	463	6	;	;	PUNCT
can-1681	463	7	165(1	165(1	NUM
can-1681	463	8	):	):	PUNCT
can-1681	463	9	82–89	82–89	NUM
can-1681	463	10	.	.	PUNCT
can-1681	464	1	75	75	NUM
can-1681	464	2	.	.	PUNCT
can-1681	465	1	wu	wu	PROPN
can-1681	465	2	z	z	PROPN
can-1681	465	3	,	,	PUNCT
can-1681	465	4	kong	kong	PROPN
can-1681	465	5	b	b	PROPN
can-1681	465	6	,	,	PUNCT
can-1681	465	7	liu	liu	PROPN
can-1681	465	8	r	r	PROPN
can-1681	465	9	,	,	PUNCT
can-1681	465	10	et	et	PROPN
can-1681	465	11	al	al	PROPN
can-1681	465	12	.	.	PUNCT
can-1681	465	13	engineering	engineering	NOUN
can-1681	465	14	of	of	ADP
can-1681	465	15	corneal	corneal	ADJ
can-1681	465	16	tissue	tissue	NOUN
can-1681	465	17	through	through	ADP
can-1681	465	18	an	an	DET
can-1681	465	19	aligned	aligned	ADJ
can-1681	465	20	pva	pva	NOUN
can-1681	465	21	/	/	SYM
can-1681	465	22	collagen	collagen	NOUN
can-1681	465	23	composite	composite	ADJ
can-1681	465	24	nanofibrous	nanofibrous	ADJ
can-1681	465	25	electrospun	electrospun	NOUN
can-1681	465	26	scaffold	scaffold	NOUN
can-1681	465	27	.	.	PUNCT
can-1681	466	1	nanomaterials	nanomaterial	NOUN
can-1681	466	2	2018	2018	NUM
can-1681	466	3	;	;	PUNCT
can-1681	466	4	8(2	8(2	NUM
can-1681	466	5	)	)	PUNCT
can-1681	466	6	.	.	PUNCT
can-1681	467	1	76	76	NUM
can-1681	467	2	.	.	PUNCT
can-1681	468	1	myung	myung	PROPN
can-1681	468	2	d	d	PROPN
can-1681	468	3	,	,	PUNCT
can-1681	468	4	duhamel	duhamel	VERB
can-1681	468	5	pe	pe	PROPN
can-1681	468	6	,	,	PUNCT
can-1681	468	7	cochran	cochran	PROPN
can-1681	468	8	jr	jr	PROPN
can-1681	468	9	,	,	PUNCT
can-1681	468	10	et	et	PROPN
can-1681	468	11	al	al	PROPN
can-1681	468	12	.	.	PUNCT
can-1681	468	13	development	development	NOUN
can-1681	468	14	of	of	ADP
can-1681	468	15	hydrogel	hydrogel	NOUN
can-1681	468	16	-	-	PUNCT
can-1681	468	17	based	base	VERB
can-1681	468	18	keratoprostheses	keratoprosthese	NOUN
can-1681	468	19	:	:	PUNCT
can-1681	468	20	a	a	DET
can-1681	468	21	materials	material	NOUN
can-1681	468	22	perspective	perspective	NOUN
can-1681	468	23	.	.	PUNCT
can-1681	469	1	biotechnological	biotechnological	ADJ
can-1681	469	2	progress	progress	NOUN
can-1681	469	3	2008	2008	NUM
can-1681	469	4	;	;	PUNCT
can-1681	469	5	24(3	24(3	NUM
can-1681	469	6	):	):	PUNCT
can-1681	469	7	735–741	735–741	NUM
can-1681	469	8	.	.	PUNCT
can-1681	470	1	77	77	NUM
can-1681	470	2	.	.	PUNCT
can-1681	471	1	zhan	zhan	PROPN
can-1681	471	2	j	j	PROPN
can-1681	471	3	,	,	PUNCT
can-1681	471	4	singh	singh	PROPN
can-1681	471	5	a	a	X
can-1681	471	6	,	,	PUNCT
can-1681	471	7	zhang	zhang	PROPN
can-1681	471	8	z	z	PROPN
can-1681	471	9	,	,	PUNCT
can-1681	471	10	et	et	PROPN
can-1681	471	11	al	al	PROPN
can-1681	471	12	.	.	PUNCT
can-1681	471	13	multifunctional	multifunctional	ADJ
can-1681	471	14	aliphatic	aliphatic	ADJ
can-1681	471	15	polyester	polyester	NOUN
can-1681	471	16	nanofibers	nanofiber	NOUN
can-1681	471	17	for	for	ADP
can-1681	471	18	tissue	tissue	NOUN
can-1681	471	19	engineering	engineering	NOUN
can-1681	471	20	.	.	PUNCT
can-1681	472	1	biomatter	biomatter	NOUN
can-1681	472	2	2012	2012	NUM
can-1681	472	3	;	;	PUNCT
can-1681	472	4	2(4	2(4	NUM
can-1681	472	5	):	):	PUNCT
can-1681	472	6	202–212	202–212	NUM
can-1681	472	7	.	.	PUNCT
can-1681	473	1	78	78	NUM
can-1681	473	2	.	.	PUNCT
can-1681	474	1	tarun	tarun	PROPN
can-1681	474	2	garg	garg	PROPN
can-1681	474	3	g	g	PROPN
can-1681	474	4	,	,	PUNCT
can-1681	474	5	malik	malik	PROPN
can-1681	474	6	b	b	PROPN
can-1681	474	7	,	,	PUNCT
can-1681	474	8	et	et	PROPN
can-1681	474	9	al	al	PROPN
can-1681	474	10	.	.	PROPN
can-1681	474	11	development	development	NOUN
can-1681	474	12	and	and	CCONJ
can-1681	474	13	characterization	characterization	NOUN
can-1681	474	14	of	of	ADP
can-1681	474	15	nano	nano	NOUN
can-1681	474	16	-	-	PUNCT
can-1681	474	17	fiber	fiber	NOUN
can-1681	474	18	patch	patch	NOUN
can-1681	474	19	for	for	ADP
can-1681	474	20	the	the	DET
can-1681	474	21	treatment	treatment	NOUN
can-1681	474	22	of	of	ADP
can-1681	474	23	glaucoma	glaucoma	NOUN
can-1681	474	24	.	.	PUNCT
can-1681	475	1	european	european	ADJ
can-1681	475	2	journal	journal	PROPN
can-1681	475	3	of	of	ADP
can-1681	475	4	pharmaceutical	pharmaceutical	NOUN
can-1681	475	5	science	science	NOUN
can-1681	475	6	2014	2014	NUM
can-1681	475	7	;	;	PUNCT
can-1681	475	8	53	53	NUM
can-1681	475	9	:	:	SYM
can-1681	475	10	10–16	10–16	NUM
can-1681	475	11	.	.	PUNCT
can-1681	476	1	78	78	NUM
can-1681	476	2	79	79	NUM
can-1681	476	3	.	.	PUNCT
can-1681	477	1	nagarwal	nagarwal	PROPN
can-1681	477	2	rc	rc	PROPN
can-1681	477	3	,	,	PUNCT
can-1681	477	4	kant	kant	PROPN
can-1681	477	5	s	s	PROPN
can-1681	477	6	,	,	PUNCT
can-1681	477	7	singh	singh	PROPN
can-1681	477	8	pn	pn	PROPN
can-1681	477	9	,	,	PUNCT
can-1681	477	10	et	et	PROPN
can-1681	477	11	al	al	PROPN
can-1681	477	12	.	.	PROPN
can-1681	477	13	polymer	polymer	NOUN
can-1681	477	14	nanoparticle	nanoparticle	NOUN
can-1681	477	15	system	system	NOUN
can-1681	477	16	:	:	PUNCT
can-1681	477	17	a	a	DET
can-1681	477	18	potential	potential	ADJ
can-1681	477	19	approach	approach	NOUN
can-1681	477	20	for	for	ADP
can-1681	477	21	ocular	ocular	ADJ
can-1681	477	22	drug	drug	NOUN
can-1681	477	23	delivery	delivery	NOUN
can-1681	477	24	.	.	PUNCT
can-1681	478	1	journal	journal	PROPN
can-1681	478	2	of	of	ADP
can-1681	478	3	control	control	PROPN
can-1681	478	4	release	release	NOUN
can-1681	478	5	2009	2009	NUM
can-1681	478	6	;	;	PUNCT
can-1681	478	7	136(1	136(1	NUM
can-1681	478	8	):	):	PUNCT
can-1681	478	9	2–13	2–13	PROPN
can-1681	478	10	.	.	PUNCT
can-1681	479	1	80	80	NUM
can-1681	479	2	.	.	PUNCT
can-1681	480	1	morrison	morrison	PROPN
can-1681	480	2	pw	pw	PROPN
can-1681	480	3	,	,	PUNCT
can-1681	480	4	khutoryanskiy	khutoryanskiy	NOUN
can-1681	480	5	vv	vv	NOUN
can-1681	480	6	.	.	PUNCT
can-1681	480	7	advances	advance	NOUN
can-1681	480	8	in	in	ADP
can-1681	480	9	ophthalmic	ophthalmic	ADJ
can-1681	480	10	drug	drug	NOUN
can-1681	480	11	delivery	delivery	NOUN
can-1681	480	12	.	.	PUNCT
can-1681	481	1	therapeutic	therapeutic	ADJ
can-1681	481	2	deliveries	delivery	NOUN
can-1681	481	3	2014	2014	NUM
can-1681	481	4	;	;	PUNCT
can-1681	481	5	5(12	5(12	NUM
can-1681	481	6	):	):	PUNCT
can-1681	481	7	1297–1315	1297–1315	NUM
can-1681	481	8	.	.	PUNCT
can-1681	482	1	81	81	NUM
can-1681	482	2	.	.	PUNCT
can-1681	483	1	diebold	diebold	PROPN
can-1681	483	2	y	y	PROPN
can-1681	483	3	,	,	PUNCT
can-1681	483	4	calonge	calonge	ADJ
can-1681	483	5	m.	m.	NOUN
can-1681	483	6	applications	application	NOUN
can-1681	483	7	of	of	ADP
can-1681	483	8	nanoparticles	nanoparticle	NOUN
can-1681	483	9	in	in	ADP
can-1681	483	10	ophthalmology	ophthalmology	NOUN
can-1681	483	11	.	.	PUNCT
can-1681	484	1	progress	progress	NOUN
can-1681	484	2	in	in	ADP
can-1681	484	3	retinal	retinal	ADJ
can-1681	484	4	and	and	CCONJ
can-1681	484	5	eye	eye	NOUN
can-1681	484	6	research	research	NOUN
can-1681	484	7	2010	2010	NUM
can-1681	484	8	;	;	PUNCT
can-1681	484	9	29(6	29(6	NUM
can-1681	484	10	):	):	PUNCT
can-1681	484	11	596–609	596–609	NUM
can-1681	484	12	.	.	PUNCT
can-1681	485	1	82	82	NUM
can-1681	485	2	.	.	PUNCT
can-1681	485	3	park	park	PROPN
can-1681	485	4	k	k	PROPN
can-1681	485	5	,	,	PUNCT
can-1681	485	6	chen	chen	PROPN
can-1681	485	7	y	y	PROPN
can-1681	485	8	,	,	PUNCT
can-1681	485	9	hu	hu	PROPN
can-1681	485	10	y	y	PROPN
can-1681	485	11	,	,	PUNCT
can-1681	485	12	et	et	PROPN
can-1681	485	13	al	al	PROPN
can-1681	485	14	.	.	PROPN
can-1681	485	15	nanoparticle	nanoparticle	NOUN
can-1681	485	16	-	-	PUNCT
can-1681	485	17	mediated	mediate	VERB
can-1681	485	18	expression	expression	NOUN
can-1681	485	19	of	of	ADP
can-1681	485	20	an	an	DET
can-1681	485	21	angiogenic	angiogenic	ADJ
can-1681	485	22	inhibitor	inhibitor	NOUN
can-1681	485	23	ameliorates	ameliorate	NOUN
can-1681	485	24	ischemia	ischemia	NOUN
can-1681	485	25	-	-	PUNCT
can-1681	485	26	induced	induce	VERB
can-1681	485	27	retinal	retinal	ADJ
can-1681	485	28	neovascularization	neovascularization	NOUN
can-1681	485	29	and	and	CCONJ
can-1681	485	30	diabetes	diabetes	NOUN
can-1681	485	31	-	-	PUNCT
can-1681	485	32	induced	induce	VERB
can-1681	485	33	retinal	retinal	ADJ
can-1681	485	34	vascular	vascular	ADJ
can-1681	485	35	leakage	leakage	NOUN
can-1681	485	36	.	.	PUNCT
can-1681	486	1	diabetes	diabetes	NOUN
can-1681	486	2	2009	2009	NUM
can-1681	486	3	;	;	PUNCT
can-1681	486	4	58(8	58(8	NUM
can-1681	486	5	):	):	PUNCT
can-1681	486	6	1902–1913	1902–1913	NUM
can-1681	486	7	.	.	PUNCT
can-1681	486	8	83	83	NUM
can-1681	486	9	.	.	PUNCT
can-1681	487	1	pozo	pozo	PROPN
can-1681	487	2	-	-	PUNCT
can-1681	487	3	rodriguez	rodriguez	PROPN
can-1681	487	4	a	a	DET
can-1681	487	5	,	,	PUNCT
can-1681	487	6	delgado	delgado	NOUN
can-1681	487	7	d	d	PROPN
can-1681	487	8	,	,	PUNCT
can-1681	487	9	gasco	gasco	PROPN
can-1681	487	10	ar	ar	PROPN
can-1681	487	11	,	,	PUNCT
can-1681	487	12	et	et	PROPN
can-1681	487	13	al	al	PROPN
can-1681	487	14	.	.	PUNCT
can-1681	487	15	lipid	lipid	PROPN
can-1681	487	16	nanoparticles	nanoparticle	NOUN
can-1681	487	17	as	as	ADP
can-1681	487	18	drug	drug	NOUN
can-1681	487	19	/	/	SYM
can-1681	487	20	gene	gene	NOUN
can-1681	487	21	delivery	delivery	NOUN
can-1681	487	22	systems	system	NOUN
can-1681	487	23	to	to	ADP
can-1681	487	24	the	the	DET
can-1681	487	25	retina	retina	NOUN
can-1681	487	26	.	.	PUNCT
can-1681	488	1	journal	journal	NOUN
can-1681	488	2	of	of	ADP
can-1681	488	3	ocular	ocular	ADJ
can-1681	488	4	pharmacology	pharmacology	NOUN
can-1681	488	5	and	and	CCONJ
can-1681	488	6	therapeutics	therapeutic	NOUN
can-1681	488	7	2013	2013	NUM
can-1681	488	8	;	;	PUNCT
can-1681	488	9	29(2	29(2	NUM
can-1681	488	10	):	):	PUNCT
can-1681	488	11	173–188	173–188	NUM
can-1681	488	12	.	.	PUNCT
can-1681	488	13	84	84	NUM
can-1681	488	14	.	.	PUNCT
can-1681	489	1	lalu	lalu	PROPN
can-1681	489	2	l	l	PROPN
can-1681	489	3	,	,	PUNCT
can-1681	489	4	tambe	tambe	ADP
can-1681	489	5	v	v	NOUN
can-1681	489	6	,	,	PUNCT
can-1681	489	7	pradhan	pradhan	PROPN
can-1681	489	8	d	d	PROPN
can-1681	489	9	,	,	PUNCT
can-1681	489	10	et	et	PROPN
can-1681	489	11	al	al	PROPN
can-1681	489	12	.	.	PROPN
can-1681	489	13	novel	novel	PROPN
can-1681	489	14	nanosystems	nanosystem	VERB
can-1681	489	15	for	for	ADP
can-1681	489	16	the	the	DET
can-1681	489	17	treatment	treatment	NOUN
can-1681	489	18	of	of	ADP
can-1681	489	19	ocular	ocular	ADJ
can-1681	489	20	inflammation	inflammation	NOUN
can-1681	489	21	:	:	PUNCT
can-1681	489	22	current	current	ADJ
can-1681	489	23	paradigms	paradigm	NOUN
can-1681	489	24	and	and	CCONJ
can-1681	489	25	future	future	ADJ
can-1681	489	26	research	research	NOUN
can-1681	489	27	directions	direction	NOUN
can-1681	489	28	.	.	PUNCT
can-1681	490	1	journal	journal	NOUN
can-1681	490	2	of	of	ADP
can-1681	490	3	controlled	control	VERB
can-1681	490	4	release	release	NOUN
can-1681	490	5	2017	2017	NUM
can-1681	490	6	:	:	PUNCT
can-1681	490	7	19–39	19–39	NUM
can-1681	490	8	.	.	NOUN
can-1681	490	9	85	85	NUM
can-1681	490	10	.	.	PUNCT
can-1681	490	11	balguri	balguri	PROPN
can-1681	490	12	sp	sp	PROPN
can-1681	490	13	,	,	PUNCT
can-1681	490	14	adelli	adelli	PROPN
can-1681	490	15	gr	gr	PROPN
can-1681	490	16	,	,	PUNCT
can-1681	490	17	majumdar	majumdar	PROPN
can-1681	490	18	s.	s.	PROPN
can-1681	490	19	topical	topical	ADJ
can-1681	490	20	ophthalmic	ophthalmic	ADJ
can-1681	490	21	lipid	lipid	NOUN
can-1681	490	22	nanoparticle	nanoparticle	NOUN
can-1681	490	23	fornulations	fornulation	NOUN
can-1681	490	24	(	(	PUNCT
can-1681	490	25	sln	sln	PROPN
can-1681	490	26	,	,	PUNCT
can-1681	490	27	nlc	nlc	PROPN
can-1681	490	28	)	)	PUNCT
can-1681	490	29	of	of	ADP
can-1681	490	30	indomethacin	indomethacin	NOUN
can-1681	490	31	for	for	ADP
can-1681	490	32	delivery	delivery	NOUN
can-1681	490	33	to	to	ADP
can-1681	490	34	the	the	DET
can-1681	490	35	posterior	posterior	ADJ
can-1681	490	36	segment	segment	NOUN
can-1681	490	37	ocular	ocular	ADJ
can-1681	490	38	tissues	tissue	NOUN
can-1681	490	39	.	.	PUNCT
can-1681	491	1	european	european	ADJ
can-1681	491	2	journal	journal	PROPN
can-1681	491	3	of	of	ADP
can-1681	491	4	pharmaceutics	pharmaceutic	NOUN
can-1681	491	5	and	and	CCONJ
can-1681	491	6	biopharmaceutics	biopharmaceutic	NOUN
can-1681	491	7	2016	2016	NUM
can-1681	491	8	;	;	PUNCT
can-1681	491	9	109	109	NUM
can-1681	491	10	:	:	SYM
can-1681	491	11	224–235	224–235	NUM
can-1681	491	12	.	.	NOUN
can-1681	491	13	86	86	NUM
can-1681	491	14	.	.	PUNCT
can-1681	492	1	zabihzadeh	zabihzadeh	PROPN
can-1681	492	2	m	m	PROPN
can-1681	492	3	,	,	PUNCT
can-1681	492	4	rezaee	rezaee	PROPN
can-1681	492	5	h	h	PROPN
can-1681	492	6	,	,	PUNCT
can-1681	492	7	hosseini	hosseini	PROPN
can-1681	492	8	sm	sm	PROPN
can-1681	492	9	,	,	PUNCT
can-1681	492	10	et	et	PROPN
can-1681	492	11	al	al	PROPN
can-1681	492	12	.	.	PUNCT
can-1681	492	13	improvement	improvement	NOUN
can-1681	492	14	of	of	ADP
can-1681	492	15	dose	dose	ADJ
can-1681	492	16	distribution	distribution	NOUN
can-1681	492	17	in	in	ADP
can-1681	492	18	ocular	ocular	ADJ
can-1681	492	19	brachytherapy	brachytherapy	NOUN
can-1681	492	20	with	with	ADP
can-1681	492	21	(	(	PUNCT
can-1681	492	22	125	125	NUM
can-1681	492	23	)	)	PUNCT
can-1681	492	24	l	l	NOUN
can-1681	492	25	seeds	seed	NOUN
can-1681	492	26	20	20	NUM
can-1681	492	27	mm	mm	PROPN
can-1681	492	28	coms	com	NOUN
can-1681	492	29	plaque	plaque	NOUN
can-1681	492	30	followed	follow	VERB
can-1681	492	31	to	to	ADP
can-1681	492	32	loading	loading	NOUN
can-1681	492	33	of	of	ADP
can-1681	492	34	choroidal	choroidal	ADJ
can-1681	492	35	tumor	tumor	NOUN
can-1681	492	36	by	by	ADP
can-1681	492	37	gold	gold	ADJ
can-1681	492	38	nanoparticles	nanoparticle	NOUN
can-1681	492	39	.	.	PUNCT
can-1681	493	1	journal	journal	NOUN
can-1681	493	2	of	of	ADP
can-1681	493	3	cancer	cancer	NOUN
can-1681	493	4	research	research	NOUN
can-1681	493	5	and	and	CCONJ
can-1681	493	6	therapeutics	therapeutic	NOUN
can-1681	493	7	2019	2019	NUM
can-1681	493	8	;	;	PUNCT
can-1681	493	9	15(3	15(3	NUM
can-1681	493	10	):	):	PUNCT
can-1681	493	11	137–146	137–146	NUM
can-1681	493	12	.	.	PUNCT
can-1681	494	1	87	87	NUM
can-1681	494	2	.	.	PUNCT
can-1681	495	1	wichterle	wichterle	PROPN
can-1681	495	2	o	o	PROPN
can-1681	495	3	,	,	PUNCT
can-1681	495	4	lim	lim	PROPN
can-1681	495	5	d	d	PROPN
can-1681	495	6	(	(	PUNCT
can-1681	495	7	inventors	inventor	NOUN
can-1681	495	8	)	)	PUNCT
can-1681	495	9	.	.	PUNCT
can-1681	496	1	crosslinked	crosslinke	VERB
can-1681	496	2	hydrophilic	hydrophilic	ADJ
can-1681	496	3	polymers	polymer	NOUN
can-1681	496	4	and	and	CCONJ
can-1681	496	5	their	their	PRON
can-1681	496	6	products	product	NOUN
can-1681	496	7	.	.	PUNCT
can-1681	497	1	us	us	PROPN
can-1681	497	2	patent	patent	NOUN
can-1681	497	3	.	.	PUNCT
can-1681	498	1	1965	1965	NUM
can-1681	498	2	.	.	PUNCT
can-1681	499	1	88	88	NUM
can-1681	499	2	.	.	PUNCT
can-1681	500	1	dubard	dubard	PROPN
can-1681	500	2	m	m	PROPN
can-1681	500	3	,	,	PUNCT
can-1681	500	4	bourgeois	bourgeois	PROPN
can-1681	500	5	s	s	PROPN
can-1681	500	6	,	,	PUNCT
can-1681	500	7	andrieu	andrieu	PROPN
can-1681	500	8	v	v	ADP
can-1681	500	9	,	,	PUNCT
can-1681	500	10	et	et	PROPN
can-1681	500	11	al	al	PROPN
can-1681	500	12	.	.	PROPN
can-1681	501	1	ophthalmic	ophthalmic	ADJ
can-1681	501	2	drug	drug	NOUN
can-1681	501	3	delivery	delivery	NOUN
can-1681	501	4	systems	system	NOUN
can-1681	501	5	for	for	ADP
can-1681	501	6	antibiotherapy	antibiotherapy	NOUN
can-1681	501	7	—	—	PUNCT
can-1681	501	8	a	a	DET
can-1681	501	9	review	review	NOUN
can-1681	501	10	.	.	PUNCT
can-1681	502	1	pharmaceutics	pharmaceutic	NOUN
can-1681	502	2	2018	2018	NUM
can-1681	502	3	;	;	PUNCT
can-1681	502	4	10(1	10(1	NUM
can-1681	502	5	)	)	PUNCT
can-1681	502	6	.	.	PUNCT
can-1681	503	1	89	89	NUM
can-1681	503	2	.	.	PUNCT
can-1681	504	1	dixon	dixon	PROPN
can-1681	504	2	p	p	PROPN
can-1681	504	3	,	,	PUNCT
can-1681	504	4	shafor	shafor	ADP
can-1681	504	5	c	c	PROPN
can-1681	504	6	,	,	PUNCT
can-1681	504	7	gauss	gauss	PROPN
can-1681	504	8	s	s	PROPN
can-1681	504	9	,	,	PUNCT
can-1681	504	10	et	et	PROPN
can-1681	504	11	al	al	PROPN
can-1681	504	12	.	.	PUNCT
can-1681	505	1	therapeutic	therapeutic	ADJ
can-1681	505	2	contact	contact	NOUN
can-1681	505	3	lenses	lense	NOUN
can-1681	505	4	:	:	PUNCT
can-1681	505	5	a	a	DET
can-1681	505	6	patent	patent	NOUN
can-1681	505	7	review	review	NOUN
can-1681	505	8	.	.	PUNCT
can-1681	506	1	expert	expert	ADJ
can-1681	506	2	opinion	opinion	NOUN
can-1681	506	3	on	on	ADP
can-1681	506	4	therapeutic	therapeutic	ADJ
can-1681	506	5	patents	patent	NOUN
can-1681	506	6	2015	2015	NUM
can-1681	506	7	;	;	PUNCT
can-1681	506	8	25(10	25(10	NUM
can-1681	506	9	):	):	PUNCT
can-1681	506	10	1117–1119	1117–1119	NUM
can-1681	506	11	.	.	PUNCT
can-1681	507	1	90	90	NUM
can-1681	507	2	.	.	PUNCT
can-1681	508	1	guzman	guzman	NOUN
can-1681	508	2	-	-	PUNCT
can-1681	508	3	aranguez	aranguez	NOUN
can-1681	508	4	a	a	X
can-1681	508	5	,	,	PUNCT
can-1681	508	6	fonseca	fonseca	PROPN
can-1681	508	7	b	b	PROPN
can-1681	508	8	,	,	PUNCT
can-1681	508	9	carracedo	carracedo	NOUN
can-1681	508	10	g	g	PROPN
can-1681	508	11	,	,	PUNCT
can-1681	508	12	et	et	PROPN
can-1681	508	13	al	al	PROPN
can-1681	508	14	.	.	PROPN
can-1681	508	15	dry	dry	PROPN
can-1681	508	16	eye	eye	NOUN
can-1681	508	17	treatment	treatment	NOUN
can-1681	508	18	based	base	VERB
can-1681	508	19	on	on	ADP
can-1681	508	20	contact	contact	NOUN
can-1681	508	21	lens	lens	NOUN
can-1681	508	22	drug	drug	NOUN
can-1681	508	23	delivery	delivery	NOUN
can-1681	508	24	:	:	PUNCT
can-1681	508	25	a	a	DET
can-1681	508	26	review	review	NOUN
can-1681	508	27	.	.	PUNCT
can-1681	509	1	eye	eye	NOUN
can-1681	509	2	&	&	CCONJ
can-1681	509	3	contact	contact	PROPN
can-1681	509	4	lens	len	NOUN
can-1681	509	5	:	:	PUNCT
can-1681	509	6	science	science	NOUN
can-1681	509	7	&	&	CCONJ
can-1681	509	8	clinical	clinical	ADJ
can-1681	509	9	practice	practice	NOUN
can-1681	509	10	2016	2016	NUM
can-1681	509	11	;	;	PUNCT
can-1681	509	12	42(5	42(5	NUM
can-1681	509	13	):	):	PUNCT
can-1681	509	14	280–288	280–288	NUM
can-1681	509	15	.	.	PUNCT
can-1681	510	1	91	91	NUM
can-1681	510	2	.	.	PUNCT
can-1681	511	1	maulvi	maulvi	PROPN
can-1681	511	2	fa	fa	PROPN
can-1681	511	3	,	,	PUNCT
can-1681	511	4	patil	patil	PROPN
can-1681	511	5	rj	rj	PROPN
can-1681	511	6	,	,	PUNCT
can-1681	511	7	desai	desai	PROPN
can-1681	511	8	ar	ar	PROPN
can-1681	511	9	,	,	PUNCT
can-1681	511	10	et	et	PROPN
can-1681	511	11	al	al	PROPN
can-1681	511	12	.	.	PROPN
can-1681	511	13	effect	effect	NOUN
can-1681	511	14	of	of	ADP
can-1681	511	15	gold	gold	ADJ
can-1681	511	16	nanoparticles	nanoparticle	NOUN
can-1681	511	17	on	on	ADP
can-1681	511	18	timolol	timolol	NOUN
can-1681	511	19	uptake	uptake	NOUN
can-1681	511	20	and	and	CCONJ
can-1681	511	21	its	its	PRON
can-1681	511	22	release	release	NOUN
can-1681	511	23	kinetics	kinetic	NOUN
can-1681	511	24	from	from	ADP
can-1681	511	25	contact	contact	NOUN
can-1681	511	26	lenses	lense	NOUN
can-1681	511	27	:	:	PUNCT
can-1681	511	28	in	in	ADP
can-1681	511	29	vitro	vitro	X
can-1681	511	30	and	and	CCONJ
can-1681	511	31	in	in	ADP
can-1681	511	32	vivo	vivo	ADJ
can-1681	511	33	evaluation	evaluation	NOUN
can-1681	511	34	.	.	PUNCT
can-1681	512	1	acta	acta	PROPN
can-1681	512	2	biomaterialia	biomaterialia	PROPN
can-1681	512	3	2019	2019	NUM
can-1681	512	4	;	;	PUNCT
can-1681	512	5	86	86	NUM
can-1681	512	6	:	:	PUNCT
can-1681	513	1	350–362	350–362	NUM
can-1681	513	2	.	.	PUNCT
can-1681	514	1	92	92	NUM
can-1681	514	2	.	.	PUNCT
can-1681	515	1	yasin	yasin	PROPN
can-1681	515	2	mn	mn	PROPN
can-1681	515	3	,	,	PUNCT
can-1681	515	4	svirskis	svirskis	PROPN
can-1681	515	5	d	d	PROPN
can-1681	515	6	,	,	PUNCT
can-1681	515	7	seyfoddin	seyfoddin	NOUN
can-1681	515	8	a	a	PRON
can-1681	515	9	,	,	PUNCT
can-1681	515	10	et	et	PROPN
can-1681	515	11	al	al	PROPN
can-1681	515	12	.	.	PUNCT
can-1681	515	13	implants	implant	NOUN
can-1681	515	14	for	for	ADP
can-1681	515	15	drugs	drug	NOUN
can-1681	515	16	delivery	delivery	NOUN
can-1681	515	17	to	to	ADP
can-1681	515	18	the	the	DET
can-1681	515	19	posterior	posterior	ADJ
can-1681	515	20	segment	segment	NOUN
can-1681	515	21	of	of	ADP
can-1681	515	22	the	the	DET
can-1681	515	23	eye	eye	NOUN
can-1681	515	24	:	:	PUNCT
can-1681	515	25	a	a	DET
can-1681	515	26	focus	focus	NOUN
can-1681	515	27	on	on	ADP
can-1681	515	28	stimuli	stimulus	NOUN
can-1681	515	29	-	-	PUNCT
can-1681	515	30	response	response	NOUN
can-1681	515	31	and	and	CCONJ
can-1681	515	32	tunable	tunable	NOUN
can-1681	515	33	release	release	NOUN
can-1681	515	34	systems	system	NOUN
can-1681	515	35	.	.	PUNCT
can-1681	516	1	journal	journal	PROPN
can-1681	516	2	of	of	ADP
can-1681	516	3	controlled	control	VERB
can-1681	516	4	release	release	NOUN
can-1681	516	5	2014	2014	NUM
can-1681	516	6	;	;	PUNCT
can-1681	516	7	196	196	NUM
can-1681	516	8	:	:	PUNCT
can-1681	516	9	208–221	208–221	NUM
can-1681	516	10	.	.	PUNCT
can-1681	517	1	93	93	NUM
can-1681	517	2	.	.	PUNCT
can-1681	518	1	bernards	bernard	NOUN
can-1681	518	2	d	d	PROPN
can-1681	518	3	,	,	PUNCT
can-1681	518	4	bhistitkul	bhistitkul	NOUN
can-1681	518	5	r	r	NOUN
can-1681	518	6	,	,	PUNCT
can-1681	518	7	deasi	deasi	NOUN
can-1681	518	8	t.	t.	NOUN
can-1681	518	9	zero	zero	NUM
can-1681	518	10	-	-	PUNCT
can-1681	518	11	order	order	NOUN
can-1681	518	12	sustained	sustain	VERB
can-1681	518	13	drug	drug	NOUN
can-1681	518	14	delivery	delivery	NOUN
can-1681	518	15	to	to	ADP
can-1681	518	16	the	the	DET
can-1681	518	17	retina	retina	NOUN
can-1681	518	18	from	from	ADP
can-1681	518	19	a	a	DET
can-1681	518	20	nanoporous	nanoporous	ADJ
can-1681	518	21	film	film	NOUN
can-1681	518	22	device	device	NOUN
can-1681	518	23	.	.	PUNCT
can-1681	519	1	journal	journal	NOUN
can-1681	519	2	of	of	ADP
can-1681	519	3	drug	drug	NOUN
can-1681	519	4	delivery	delivery	NOUN
can-1681	519	5	2014	2014	NUM
can-1681	519	6	;	;	PUNCT
can-1681	519	7	48	48	NUM
can-1681	519	8	:	:	SYM
can-1681	519	9	20	20	NUM
can-1681	519	10	–	–	PUNCT
can-1681	519	11	21	21	NUM
can-1681	519	12	.	.	PUNCT
can-1681	519	13	94	94	NUM
can-1681	519	14	.	.	PUNCT
can-1681	520	1	lance	lance	PROPN
can-1681	520	2	kd	kd	PROPN
can-1681	520	3	,	,	PUNCT
can-1681	520	4	good	good	ADJ
can-1681	520	5	sd	sd	NOUN
can-1681	520	6	,	,	PUNCT
can-1681	520	7	mendes	mende	NOUN
can-1681	520	8	ts	ts	VERB
can-1681	520	9	,	,	PUNCT
can-1681	520	10	et	et	PROPN
can-1681	520	11	al	al	PROPN
can-1681	520	12	.	.	PROPN
can-1681	521	1	in	in	ADP
can-1681	521	2	vitro	vitro	X
can-1681	521	3	and	and	CCONJ
can-1681	521	4	in	in	ADP
can-1681	521	5	vivo	vivo	NOUN
can-1681	521	6	sustained	sustain	VERB
can-1681	521	7	zero	zero	NUM
can-1681	521	8	-	-	PUNCT
can-1681	521	9	order	order	NOUN
can-1681	521	10	delivery	delivery	NOUN
can-1681	521	11	of	of	ADP
can-1681	521	12	rapamycin	rapamycin	NOUN
can-1681	521	13	(	(	PUNCT
can-1681	521	14	sirolimus	sirolimus	NOUN
can-1681	521	15	)	)	PUNCT
can-1681	521	16	from	from	ADP
can-1681	521	17	a	a	DET
can-1681	521	18	biodegradable	biodegradable	ADJ
can-1681	521	19	intraocular	intraocular	ADJ
can-1681	521	20	device	device	NOUN
can-1681	521	21	.	.	PUNCT
can-1681	522	1	invest	invest	VERB
can-1681	522	2	ophthalmol	ophthalmol	PROPN
can-1681	522	3	visual	visual	ADJ
can-1681	522	4	science	science	NOUN
can-1681	522	5	2015	2015	NUM
can-1681	522	6	;	;	PUNCT
can-1681	522	7	56(12	56(12	NUM
can-1681	522	8	):	):	PUNCT
can-1681	522	9	7331–7337	7331–7337	NUM
can-1681	522	10	.	.	PUNCT
can-1681	523	1	95	95	NUM
can-1681	523	2	.	.	PUNCT
can-1681	524	1	sharaf	sharaf	PROPN
can-1681	524	2	mg	mg	PROPN
can-1681	524	3	,	,	PUNCT
can-1681	524	4	cetinel	cetinel	NOUN
can-1681	524	5	s	s	PROPN
can-1681	524	6	,	,	PUNCT
can-1681	524	7	heckler	heckler	NOUN
can-1681	524	8	l	l	NOUN
can-1681	524	9	,	,	PUNCT
can-1681	524	10	et	et	PROPN
can-1681	524	11	al	al	PROPN
can-1681	524	12	.	.	PUNCT
can-1681	525	1	nanotechnology	nanotechnology	PROPN
can-1681	525	2	-	-	PUNCT
can-1681	525	3	based	base	VERB
can-1681	525	4	approaches	approach	NOUN
can-1681	525	5	for	for	ADP
can-1681	525	6	ophthalmology	ophthalmology	NOUN
can-1681	525	7	applications	application	NOUN
can-1681	525	8	:	:	PUNCT
can-1681	525	9	therapeutic	therapeutic	ADJ
can-1681	525	10	and	and	CCONJ
can-1681	525	11	diagnostic	diagnostic	ADJ
can-1681	525	12	strategies	strategy	NOUN
can-1681	525	13	.	.	PUNCT
can-1681	526	1	asia	asia	PROPN
can-1681	526	2	-	-	PUNCT
can-1681	526	3	pacific	pacific	PROPN
can-1681	526	4	journal	journal	NOUN
can-1681	526	5	of	of	ADP
can-1681	526	6	ophthalmology	ophthalmology	NOUN
can-1681	526	7	2014	2014	NUM
can-1681	526	8	;	;	PUNCT
can-1681	526	9	3(3	3(3	NUM
can-1681	526	10	):	):	PUNCT
can-1681	526	11	172–180	172–180	NUM
can-1681	526	12	.	.	PUNCT
can-1681	527	1	96	96	NUM
can-1681	527	2	.	.	PUNCT
can-1681	528	1	bachu	bachu	PROPN
can-1681	528	2	rd	rd	PROPN
can-1681	528	3	,	,	PUNCT
can-1681	528	4	chowdhury	chowdhury	PROPN
can-1681	528	5	p	p	PRON
can-1681	528	6	,	,	PUNCT
can-1681	528	7	al	al	PROPN
can-1681	528	8	-	-	PUNCT
can-1681	528	9	saedi	saedi	PROPN
can-1681	528	10	zhf	zhf	PROPN
can-1681	528	11	,	,	PUNCT
can-1681	528	12	et	et	PROPN
can-1681	528	13	al	al	PROPN
can-1681	528	14	.	.	PROPN
can-1681	528	15	ocular	ocular	ADJ
can-1681	528	16	drug	drug	NOUN
can-1681	528	17	delivery	delivery	NOUN
can-1681	528	18	barriers	barrier	NOUN
can-1681	528	19	-	-	PUNCT
can-1681	528	20	role	role	NOUN
can-1681	528	21	of	of	ADP
can-1681	528	22	nanocarriers	nanocarrier	NOUN
can-1681	528	23	in	in	ADP
can-1681	528	24	the	the	DET
can-1681	528	25	treatment	treatment	NOUN
can-1681	528	26	of	of	ADP
can-1681	528	27	anterior	anterior	ADJ
can-1681	528	28	segment	segment	NOUN
can-1681	528	29	diseases	disease	NOUN
can-1681	528	30	.	.	PUNCT
can-1681	529	1	pharmaceutics	pharmaceutic	NOUN
can-1681	529	2	2018	2018	NUM
can-1681	529	3	;	;	PUNCT
can-1681	529	4	10(1	10(1	NUM
can-1681	529	5	)	)	PUNCT
can-1681	529	6	.	.	PUNCT
can-1681	530	1	97	97	NUM
can-1681	530	2	.	.	PUNCT
can-1681	531	1	campos	campos	PROPN
can-1681	531	2	am	be	AUX
can-1681	531	3	,	,	PUNCT
can-1681	531	4	sanchez	sanchez	PROPN
can-1681	531	5	a	a	PROPN
can-1681	531	6	,	,	PUNCT
can-1681	531	7	alonso	alonso	PROPN
can-1681	531	8	mj	mj	PROPN
can-1681	531	9	.	.	PUNCT
can-1681	532	1	chitosan	chitosan	NOUN
can-1681	532	2	nanoparticles	nanoparticle	NOUN
can-1681	532	3	:	:	PUNCT
can-1681	532	4	a	a	DET
can-1681	532	5	new	new	ADJ
can-1681	532	6	vehicle	vehicle	NOUN
can-1681	532	7	for	for	ADP
can-1681	532	8	the	the	DET
can-1681	532	9	improvement	improvement	NOUN
can-1681	532	10	of	of	ADP
can-1681	532	11	the	the	DET
can-1681	532	12	delivery	delivery	NOUN
can-1681	532	13	of	of	ADP
can-1681	532	14	drugs	drug	NOUN
can-1681	532	15	to	to	ADP
can-1681	532	16	the	the	DET
can-1681	532	17	ocular	ocular	ADJ
can-1681	532	18	surface	surface	NOUN
can-1681	532	19	.	.	PUNCT
can-1681	533	1	application	application	NOUN
can-1681	533	2	of	of	ADP
can-1681	533	3	cyclosporine	cyclosporine	ADJ
can-1681	533	4	a.	a.	PROPN
can-1681	533	5	international	international	PROPN
can-1681	533	6	journal	journal	PROPN
can-1681	533	7	of	of	ADP
can-1681	533	8	pharmacy	pharmacy	NOUN
can-1681	533	9	2001	2001	NUM
can-1681	533	10	;	;	PUNCT
can-1681	533	11	224(1–2	224(1–2	NUM
can-1681	533	12	):	):	PUNCT
can-1681	533	13	159–168	159–168	NUM
can-1681	533	14	.	.	PUNCT
can-1681	533	15	98	98	NUM
can-1681	533	16	.	.	PUNCT
can-1681	534	1	babizhayev	babizhayev	PROPN
can-1681	534	2	ma	ma	PROPN
can-1681	534	3	.	.	PROPN
can-1681	534	4	coated	coat	VERB
can-1681	534	5	with	with	ADP
can-1681	534	6	nanomaterials	nanomaterial	NOUN
can-1681	534	7	intraocular	intraocular	ADJ
can-1681	534	8	lenses	lense	NOUN
can-1681	534	9	,	,	PUNCT
can-1681	534	10	ophthalmic	ophthalmic	ADJ
can-1681	534	11	and	and	CCONJ
can-1681	534	12	human	human	ADJ
can-1681	534	13	body	body	NOUN
can-1681	534	14	implantable	implantable	ADJ
can-1681	534	15	devices	device	NOUN
can-1681	534	16	with	with	ADP
can-1681	534	17	high	high	ADJ
can-1681	534	18	catalytic	catalytic	ADJ
can-1681	534	19	antioxidant	antioxidant	NOUN
can-1681	534	20	activities	activity	NOUN
can-1681	534	21	:	:	PUNCT
can-1681	534	22	a	a	DET
can-1681	534	23	new	new	ADJ
can-1681	534	24	nanotechnology	nanotechnology	NOUN
can-1681	534	25	strategy	strategy	NOUN
can-1681	534	26	of	of	ADP
can-1681	534	27	peroxidase	peroxidase	ADJ
can-1681	534	28	cellular	cellular	ADJ
can-1681	534	29	enzyme	enzyme	NOUN
can-1681	534	30	mimics	mimic	VERB
can-1681	534	31	increasing	increase	VERB
can-1681	534	32	the	the	DET
can-1681	534	33	biocompatibility	biocompatibility	NOUN
can-1681	534	34	and	and	CCONJ
can-1681	534	35	therapeutic	therapeutic	ADJ
can-1681	534	36	deployment	deployment	NOUN
can-1681	534	37	of	of	ADP
can-1681	534	38	the	the	DET
can-1681	534	39	medical	medical	ADJ
can-1681	534	40	prosthetic	prosthetic	ADJ
can-1681	534	41	device	device	NOUN
can-1681	534	42	.	.	PUNCT
can-1681	535	1	recent	recent	ADJ
can-1681	535	2	patents	patent	NOUN
can-1681	535	3	on	on	ADP
can-1681	535	4	drug	drug	NOUN
can-1681	535	5	delivery	delivery	NOUN
can-1681	535	6	&	&	CCONJ
can-1681	535	7	formulation	formulation	NOUN
can-1681	535	8	2013	2013	NUM
can-1681	535	9	;	;	PUNCT
can-1681	535	10	7(1	7(1	NUM
can-1681	535	11	):	):	PUNCT
can-1681	535	12	39–65	39–65	NUM
can-1681	535	13	.	.	NOUN
can-1681	536	1	99	99	NUM
can-1681	536	2	.	.	PUNCT
can-1681	536	3	ochiutto	ochiutto	NOUN
can-1681	536	4	ml	ml	PROPN
can-1681	536	5	,	,	PUNCT
can-1681	536	6	maranhao	maranhao	PROPN
can-1681	536	7	rc	rc	PROPN
can-1681	536	8	,	,	PUNCT
can-1681	536	9	costa	costa	PROPN
can-1681	536	10	vp	vp	PROPN
can-1681	536	11	,	,	PUNCT
can-1681	536	12	et	et	PROPN
can-1681	536	13	al	al	PROPN
can-1681	536	14	.	.	PROPN
can-1681	536	15	nanotechnology	nanotechnology	PROPN
can-1681	536	16	for	for	ADP
can-1681	536	17	medical	medical	ADJ
can-1681	536	18	and	and	CCONJ
can-1681	536	19	surgical	surgical	ADJ
can-1681	536	20	glaucoma	glaucoma	NOUN
can-1681	536	21	therapy	therapy	NOUN
can-1681	536	22	—	—	PUNCT
can-1681	536	23	a	a	DET
can-1681	536	24	review	review	NOUN
can-1681	536	25	.	.	PUNCT
can-1681	537	1	advances	advance	NOUN
can-1681	537	2	in	in	ADP
can-1681	537	3	therapy	therapy	NOUN
can-1681	537	4	2020	2020	NUM
can-1681	537	5	;	;	PUNCT
can-1681	537	6	37(1	37(1	NUM
can-1681	537	7	):	):	PUNCT
can-1681	537	8	155–199	155–199	NUM
can-1681	537	9	.	.	NOUN
can-1681	537	10	100	100	NUM
can-1681	537	11	.	.	PUNCT
can-1681	538	1	badiee	badiee	PROPN
can-1681	538	2	p	p	X
can-1681	538	3	,	,	PUNCT
can-1681	538	4	varshochian	varshochian	PROPN
can-1681	538	5	r	r	PROPN
can-1681	538	6	,	,	PUNCT
can-1681	538	7	rafiee	rafiee	PROPN
can-1681	538	8	tehrani	tehrani	PROPN
can-1681	538	9	m	m	PROPN
can-1681	538	10	,	,	PUNCT
can-1681	538	11	et	et	PROPN
can-1681	538	12	al	al	PROPN
can-1681	538	13	.	.	PROPN
can-1681	539	1	ocular	ocular	ADJ
can-1681	539	2	implant	implant	NOUN
can-1681	539	3	containing	contain	VERB
can-1681	539	4	bevacizumab	bevacizumab	NOUN
can-1681	539	5	-	-	PUNCT
can-1681	539	6	loaded	load	VERB
can-1681	539	7	chitosan	chitosan	NOUN
can-1681	539	8	nanoparticles	nanoparticle	NOUN
can-1681	539	9	intended	intend	VERB
can-1681	539	10	for	for	ADP
can-1681	539	11	choroidal	choroidal	ADJ
can-1681	539	12	neovascularization	neovascularization	NOUN
can-1681	539	13	treatment	treatment	NOUN
can-1681	539	14	.	.	PUNCT
can-1681	540	1	journal	journal	PROPN
can-1681	540	2	of	of	ADP
can-1681	540	3	biomed	biome	VERB
can-1681	540	4	materials	material	NOUN
can-1681	540	5	research	research	NOUN
can-1681	540	6	part	part	NOUN
can-1681	540	7	a	a	DET
can-1681	540	8	2018	2018	NUM
can-1681	540	9	;	;	PUNCT
can-1681	540	10	106(8	106(8	NUM
can-1681	540	11	):	):	PUNCT
can-1681	540	12	2261–2271	2261–2271	NUM
can-1681	540	13	.	.	PUNCT
can-1681	541	1	101	101	NUM
can-1681	541	2	.	.	PUNCT
can-1681	542	1	huu	huu	PROPN
can-1681	542	2	va	va	PROPN
can-1681	542	3	,	,	PUNCT
can-1681	542	4	luo	luo	PROPN
can-1681	542	5	j	j	PROPN
can-1681	542	6	,	,	PUNCT
can-1681	542	7	zhu	zhu	PROPN
can-1681	542	8	j	j	PROPN
can-1681	542	9	,	,	PUNCT
can-1681	542	10	et	et	PROPN
can-1681	542	11	al	al	PROPN
can-1681	542	12	.	.	PUNCT
can-1681	543	1	light	light	ADJ
can-1681	543	2	-	-	PUNCT
can-1681	543	3	responsive	responsive	ADJ
can-1681	543	4	nanoparticle	nanoparticle	NOUN
can-1681	543	5	depot	depot	NOUN
can-1681	543	6	to	to	PART
can-1681	543	7	control	control	VERB
can-1681	543	8	release	release	NOUN
can-1681	543	9	of	of	ADP
can-1681	543	10	a	a	DET
can-1681	543	11	small	small	ADJ
can-1681	543	12	molecule	molecule	NOUN
can-1681	543	13	angiogenesis	angiogenesis	NOUN
can-1681	543	14	inhibitor	inhibitor	NOUN
can-1681	543	15	in	in	ADP
can-1681	543	16	the	the	DET
can-1681	543	17	posterior	posterior	ADJ
can-1681	543	18	segment	segment	NOUN
can-1681	543	19	of	of	ADP
can-1681	543	20	the	the	DET
can-1681	543	21	eye	eye	NOUN
can-1681	543	22	.	.	PUNCT
can-1681	544	1	journal	journal	PROPN
can-1681	544	2	of	of	ADP
can-1681	544	3	controlled	control	VERB
can-1681	544	4	release	release	NOUN
can-1681	544	5	2015	2015	NUM
can-1681	544	6	;	;	PUNCT
can-1681	544	7	200	200	NUM
can-1681	544	8	:	:	PUNCT
can-1681	544	9	71–77	71–77	NUM
can-1681	544	10	.	.	X
can-1681	545	1	102	102	NUM
can-1681	545	2	.	.	PUNCT
can-1681	546	1	aleassa	aleassa	PROPN
can-1681	546	2	em	em	PRON
can-1681	546	3	,	,	PUNCT
can-1681	546	4	xing	xing	PROPN
can-1681	546	5	m	m	PROPN
can-1681	546	6	,	,	PUNCT
can-1681	546	7	keijzer	keijzer	PROPN
can-1681	546	8	r.	r.	PROPN
can-1681	546	9	nanomedicine	nanomedicine	PROPN
can-1681	546	10	as	as	ADP
can-1681	546	11	an	an	DET
can-1681	546	12	innovative	innovative	ADJ
can-1681	546	13	therapeutic	therapeutic	ADJ
can-1681	546	14	strategy	strategy	NOUN
can-1681	546	15	for	for	ADP
can-1681	546	16	pediatric	pediatric	ADJ
can-1681	546	17	cancer	cancer	NOUN
can-1681	546	18	.	.	PUNCT
can-1681	547	1	pediatric	pediatric	ADJ
can-1681	547	2	surgery	surgery	NOUN
can-1681	547	3	international	international	PROPN
can-1681	547	4	2015	2015	NUM
can-1681	547	5	;	;	PUNCT
can-1681	547	6	31(7	31(7	NUM
can-1681	547	7	):	):	PUNCT
can-1681	547	8	611–616	611–616	NUM
can-1681	547	9	.	.	PUNCT
can-1681	547	10	103	103	NUM
can-1681	547	11	.	.	PUNCT
can-1681	548	1	kim	kim	PROPN
can-1681	548	2	jh	jh	PROPN
can-1681	548	3	,	,	PUNCT
can-1681	548	4	kim	kim	PROPN
can-1681	548	5	mh	mh	PROPN
can-1681	548	6	,	,	PUNCT
can-1681	548	7	jo	jo	PROPN
can-1681	548	8	dh	dh	PROPN
can-1681	548	9	,	,	PUNCT
can-1681	548	10	et	et	PROPN
can-1681	548	11	al	al	PROPN
can-1681	548	12	.	.	PUNCT
can-1681	549	1	the	the	DET
can-1681	549	2	inhibition	inhibition	NOUN
can-1681	549	3	of	of	ADP
can-1681	549	4	retinal	retinal	ADJ
can-1681	549	5	neovascularization	neovascularization	NOUN
can-1681	549	6	by	by	ADP
can-1681	549	7	gold	gold	ADJ
can-1681	549	8	nanoparticles	nanoparticle	NOUN
can-1681	549	9	via	via	ADP
can-1681	549	10	suppression	suppression	NOUN
can-1681	549	11	of	of	ADP
can-1681	549	12	vegfr-2	vegfr-2	NUM
can-1681	549	13	activation	activation	NOUN
can-1681	549	14	.	.	PUNCT
can-1681	550	1	biomaterials	biomaterial	NOUN
can-1681	550	2	2011	2011	NUM
can-1681	550	3	;	;	PUNCT
can-1681	550	4	32(7	32(7	NUM
can-1681	550	5	):	):	PUNCT
can-1681	550	6	1865–1871	1865–1871	NUM
can-1681	550	7	.	.	PUNCT
can-1681	551	1	104	104	NUM
can-1681	551	2	.	.	PUNCT
can-1681	552	1	son	son	PROPN
can-1681	552	2	m	m	PROPN
can-1681	552	3	,	,	PUNCT
can-1681	552	4	kim	kim	PROPN
can-1681	552	5	d	d	PROPN
can-1681	552	6	,	,	PUNCT
can-1681	552	7	park	park	NOUN
can-1681	552	8	ks	ks	PROPN
can-1681	552	9	,	,	PUNCT
can-1681	552	10	et	et	PROPN
can-1681	552	11	al	al	PROPN
can-1681	552	12	.	.	PUNCT
can-1681	552	13	detection	detection	NOUN
can-1681	552	14	of	of	ADP
can-1681	552	15	aquaporin-4	aquaporin-4	NUM
can-1681	552	16	antibody	antibody	NOUN
can-1681	552	17	using	use	VERB
can-1681	552	18	aquaporin-4	aquaporin-4	NUM
can-1681	552	19	extracellular	extracellular	ADJ
can-1681	552	20	loop	loop	NOUN
can-1681	552	21	-	-	PUNCT
can-1681	552	22	based	base	VERB
can-1681	552	23	carbon	carbon	NOUN
can-1681	552	24	nanotube	nanotube	NOUN
can-1681	552	25	biosensor	biosensor	NOUN
can-1681	552	26	for	for	ADP
can-1681	552	27	the	the	DET
can-1681	552	28	diagnosis	diagnosis	NOUN
can-1681	552	29	of	of	ADP
can-1681	552	30	neuromyelitis	neuromyelitis	PROPN
can-1681	552	31	optica	optica	PROPN
can-1681	552	32	.	.	PUNCT
can-1681	553	1	biosensors	biosensor	NOUN
can-1681	553	2	ioelectronics	ioelectronic	NOUN
can-1681	553	3	2016	2016	NUM
can-1681	553	4	;	;	PUNCT
can-1681	553	5	78	78	NUM
can-1681	553	6	:	:	PUNCT
can-1681	553	7	87–91	87–91	NUM
can-1681	553	8	.	.	PUNCT
can-1681	554	1	105	105	NUM
can-1681	554	2	.	.	PUNCT
can-1681	554	3	silva	silva	PROPN
can-1681	554	4	nc	nc	PROPN
can-1681	554	5	,	,	PUNCT
can-1681	554	6	silva	silva	PROPN
can-1681	554	7	s	s	PROPN
can-1681	554	8	,	,	PUNCT
can-1681	554	9	sarmento	sarmento	NOUN
can-1681	554	10	b	b	PROPN
can-1681	554	11	,	,	PUNCT
can-1681	554	12	et	et	PROPN
can-1681	554	13	al	al	PROPN
can-1681	554	14	.	.	PUNCT
can-1681	555	1	chitosan	chitosan	NOUN
can-1681	555	2	nanoparticles	nanoparticle	NOUN
can-1681	555	3	for	for	ADP
can-1681	555	4	daptomycin	daptomycin	NOUN
can-1681	555	5	delivery	delivery	NOUN
can-1681	555	6	in	in	ADP
can-1681	555	7	ocular	ocular	ADJ
can-1681	555	8	treatment	treatment	NOUN
can-1681	555	9	of	of	ADP
can-1681	555	10	bacterial	bacterial	ADJ
can-1681	555	11	endophthalmitis	endophthalmitis	NOUN
can-1681	555	12	.	.	PUNCT
can-1681	556	1	drug	drug	NOUN
can-1681	556	2	delivery	delivery	NOUN
can-1681	556	3	2015	2015	NUM
can-1681	556	4	;	;	PUNCT
can-1681	556	5	22(7	22(7	NUM
can-1681	556	6	):	):	PUNCT
can-1681	556	7	885–893	885–893	NUM
can-1681	556	8	.	.	PUNCT