id	sid	tid	token	lemma	pos
can-224	1	1	12	12	NUM
can-224	1	2	copyright	copyright	NOUN
can-224	1	3	©	©	PROPN
can-224	1	4	2018	2018	NUM
can-224	1	5	-	-	PUNCT
can-224	1	6	.	.	PUNCT
can-224	2	1	this	this	PRON
can-224	2	2	is	be	AUX
can-224	2	3	an	an	DET
can-224	2	4	open	open	ADJ
can-224	2	5	access	access	NOUN
can-224	2	6	article	article	NOUN
can-224	2	7	distributed	distribute	VERB
can-224	2	8	under	under	ADP
can-224	2	9	the	the	DET
can-224	2	10	terms	term	NOUN
can-224	2	11	of	of	ADP
can-224	2	12	the	the	DET
can-224	2	13	creative	creative	ADJ
can-224	2	14	commons	common	NOUN
can-224	2	15	attribution	attribution	NOUN
can-224	2	16	-	-	PUNCT
can-224	2	17	noncommercial	noncommercial	ADJ
can-224	2	18	4.0	4.0	NUM
can-224	2	19	international	international	ADJ
can-224	2	20	license	license	NOUN
can-224	2	21	(	(	PUNCT
can-224	2	22	http://creativecommons.org/licenses/by-nc/4.0/	http://creativecommons.org/licenses/by-nc/4.0/	NOUN
can-224	2	23	)	)	PUNCT
can-224	2	24	,	,	PUNCT
can-224	2	25	permitting	permit	VERB
can-224	2	26	all	all	DET
can-224	2	27	non	non	ADJ
can-224	2	28	-	-	ADJ
can-224	2	29	commercial	commercial	ADJ
can-224	2	30	use	use	NOUN
can-224	2	31	,	,	PUNCT
can-224	2	32	distribution	distribution	NOUN
can-224	2	33	,	,	PUNCT
can-224	2	34	and	and	CCONJ
can-224	2	35	reproduction	reproduction	NOUN
can-224	2	36	in	in	ADP
can-224	2	37	any	any	DET
can-224	2	38	medium	medium	NOUN
can-224	2	39	,	,	PUNCT
can-224	2	40	provided	provide	VERB
can-224	2	41	the	the	DET
can-224	2	42	original	original	ADJ
can-224	2	43	work	work	NOUN
can-224	2	44	is	be	AUX
can-224	2	45	properly	properly	ADV
can-224	2	46	cited	cite	VERB
can-224	2	47	.	.	PUNCT
can-224	3	1	characterization	characterization	NOUN
can-224	3	2	and	and	CCONJ
can-224	3	3	application	application	NOUN
can-224	3	4	of	of	ADP
can-224	3	5	nanomaterials（2018	nanomaterials（2018	NOUN
can-224	3	6	）	）	ADJ
can-224	3	7	original	original	ADJ
can-224	3	8	research	research	NOUN
can-224	3	9	article	article	NOUN
can-224	3	10	advances	advance	VERB
can-224	3	11	in	in	ADP
can-224	3	12	synthesis	synthesis	NOUN
can-224	3	13	and	and	CCONJ
can-224	3	14	application	application	NOUN
can-224	3	15	of	of	ADP
can-224	3	16	nanometer	nanometer	NOUN
can-224	3	17	drug	drug	NOUN
can-224	3	18	carriers	carrier	NOUN
can-224	3	19	jianping	jianping	PROPN
can-224	3	20	wu	wu	PROPN
can-224	3	21	,	,	PUNCT
can-224	3	22	keming	keme	VERB
can-224	3	23	wang	wang	PROPN
can-224	3	24	,	,	PUNCT
can-224	3	25	yuquan	yuquan	PROPN
can-224	3	26	peng	peng	PROPN
can-224	3	27	school	school	PROPN
can-224	3	28	of	of	ADP
can-224	3	29	pharmaceutical	pharmaceutical	NOUN
can-224	3	30	engineering	engineering	NOUN
can-224	3	31	technology	technology	NOUN
can-224	3	32	,	,	PUNCT
can-224	3	33	jiaxing	jiaxing	PROPN
can-224	3	34	university	university	PROPN
can-224	3	35	of	of	ADP
can-224	3	36	applied	apply	VERB
can-224	3	37	science	science	NOUN
can-224	3	38	and	and	CCONJ
can-224	3	39	technology	technology	NOUN
can-224	3	40	,	,	PUNCT
can-224	3	41	zhejiang	zhejiang	PROPN
can-224	3	42	,	,	PUNCT
can-224	3	43	china	china	PROPN
can-224	3	44	abstract	abstract	ADJ
can-224	3	45	the	the	DET
can-224	3	46	main	main	ADJ
can-224	3	47	reason	reason	NOUN
can-224	3	48	for	for	ADP
can-224	3	49	the	the	DET
can-224	3	50	formation	formation	NOUN
can-224	3	51	of	of	ADP
can-224	3	52	nano	nano	NOUN
can-224	3	53	-	-	PUNCT
can-224	3	54	biotechnology	biotechnology	NOUN
can-224	3	55	is	be	AUX
can-224	3	56	due	due	ADJ
can-224	3	57	to	to	ADP
can-224	3	58	the	the	DET
can-224	3	59	penetration	penetration	NOUN
can-224	3	60	of	of	ADP
can-224	3	61	nanotechnology	nanotechnology	NOUN
can-224	3	62	in	in	ADP
can-224	3	63	the	the	DET
can-224	3	64	biological	biological	ADJ
can-224	3	65	fi	fi	NOUN
can-224	3	66	eld	eld	NOUN
can-224	3	67	,	,	PUNCT
can-224	3	68	nanotechnology	nanotechnology	NOUN
can-224	3	69	research	research	NOUN
can-224	3	70	center	center	NOUN
can-224	3	71	is	be	AUX
can-224	3	72	the	the	DET
can-224	3	73	study	study	NOUN
can-224	3	74	of	of	ADP
can-224	3	75	nano	nano	NOUN
can-224	3	76	-	-	PUNCT
can-224	3	77	drug	drug	NOUN
can-224	3	78	carrier	carrier	NOUN
can-224	3	79	.	.	PUNCT
can-224	4	1	nano	nano	NOUN
can-224	4	2	-	-	PUNCT
can-224	4	3	drug	drug	NOUN
can-224	4	4	system	system	NOUN
can-224	4	5	targeted	target	VERB
can-224	4	6	drug	drug	NOUN
can-224	4	7	delivery	delivery	NOUN
can-224	4	8	to	to	PART
can-224	4	9	achieve	achieve	VERB
can-224	4	10	drug	drug	NOUN
can-224	4	11	release	release	NOUN
can-224	4	12	,	,	PUNCT
can-224	4	13	increase	increase	VERB
can-224	4	14	the	the	DET
can-224	4	15	insoluble	insoluble	ADJ
can-224	4	16	drugs	drug	NOUN
can-224	4	17	and	and	CCONJ
can-224	4	18	peptide	peptide	ADJ
can-224	4	19	drug	drug	NOUN
can-224	4	20	bio	bio	PROPN
can-224	4	21	-	-	PUNCT
can-224	4	22	effi	effi	PROPN
can-224	4	23	ciency	ciency	NOUN
can-224	4	24	,	,	PUNCT
can-224	4	25	reduce	reduce	VERB
can-224	4	26	the	the	DET
can-224	4	27	toxicity	toxicity	NOUN
can-224	4	28	and	and	CCONJ
can-224	4	29	application	application	NOUN
can-224	4	30	of	of	ADP
can-224	4	31	drugs	drug	NOUN
can-224	4	32	and	and	CCONJ
can-224	4	33	other	other	ADJ
can-224	4	34	aspects	aspect	NOUN
can-224	4	35	of	of	ADP
can-224	4	36	the	the	DET
can-224	4	37	development	development	NOUN
can-224	4	38	of	of	ADP
can-224	4	39	good	good	ADJ
can-224	4	40	prospects	prospect	NOUN
can-224	4	41	,	,	PUNCT
can-224	4	42	and	and	CCONJ
can-224	4	43	thus	thus	ADV
can-224	4	44	become	become	VERB
can-224	4	45	one	one	NUM
can-224	4	46	of	of	ADP
can-224	4	47	the	the	DET
can-224	4	48	key	key	ADJ
can-224	4	49	research	research	NOUN
can-224	4	50	in	in	ADP
can-224	4	51	recent	recent	ADJ
can-224	4	52	years	year	NOUN
can-224	4	53	’	’	PART
can-224	4	54	fi	fi	NOUN
can-224	4	55	eld	eld	NOUN
can-224	4	56	.	.	PUNCT
can-224	4	57	synthesis	synthesis	NOUN
can-224	4	58	and	and	CCONJ
can-224	4	59	application	application	NOUN
can-224	4	60	of	of	ADP
can-224	4	61	nanometer	nanometer	NOUN
can-224	4	62	drug	drug	NOUN
can-224	4	63	carriers	carrier	NOUN
can-224	4	64	this	this	DET
can-224	4	65	review	review	NOUN
can-224	4	66	is	be	AUX
can-224	4	67	presented	present	VERB
can-224	4	68	in	in	ADP
can-224	4	69	recent	recent	ADJ
can-224	4	70	years	year	NOUN
can-224	4	71	and	and	CCONJ
can-224	4	72	its	its	PRON
can-224	4	73	application	application	NOUN
can-224	4	74	to	to	PART
can-224	4	75	provide	provide	VERB
can-224	4	76	a	a	DET
can-224	4	77	comprehensive	comprehensive	ADJ
can-224	4	78	basis	basis	NOUN
can-224	4	79	for	for	ADP
can-224	4	80	the	the	DET
can-224	4	81	treatment	treatment	NOUN
can-224	4	82	process	process	NOUN
can-224	4	83	.	.	PUNCT
can-224	5	1	describes	describe	VERB
can-224	5	2	the	the	DET
can-224	5	3	nature	nature	NOUN
can-224	5	4	and	and	CCONJ
can-224	5	5	preparation	preparation	NOUN
can-224	5	6	of	of	ADP
can-224	5	7	nano	nano	NOUN
can-224	5	8	-	-	PUNCT
can-224	5	9	drug	drug	NOUN
can-224	5	10	carrier	carrier	NOUN
can-224	5	11	methods	method	NOUN
can-224	5	12	,	,	PUNCT
can-224	5	13	in	in	ADP
can-224	5	14	recent	recent	ADJ
can-224	5	15	years	year	NOUN
can-224	5	16	,	,	PUNCT
can-224	5	17	people	people	NOUN
can-224	5	18	have	have	AUX
can-224	5	19	been	be	AUX
can-224	5	20	widely	widely	ADV
can-224	5	21	concerned	concern	VERB
can-224	5	22	by	by	ADP
can-224	5	23	scholars	scholar	NOUN
can-224	5	24	.	.	PUNCT
can-224	6	1	compared	compare	VERB
can-224	6	2	with	with	ADP
can-224	6	3	the	the	DET
can-224	6	4	nano	nano	NOUN
can-224	6	5	-	-	PUNCT
can-224	6	6	drug	drug	NOUN
can-224	6	7	delivery	delivery	NOUN
can-224	6	8	,	,	PUNCT
can-224	6	9	the	the	DET
can-224	6	10	general	general	ADJ
can-224	6	11	pharmaceutical	pharmaceutical	NOUN
can-224	6	12	can	can	AUX
can-224	6	13	not	not	PART
can-224	6	14	have	have	VERB
can-224	6	15	to	to	PART
can-224	6	16	extend	extend	VERB
can-224	6	17	the	the	DET
can-224	6	18	role	role	NOUN
can-224	6	19	of	of	ADP
can-224	6	20	drugs	drug	NOUN
can-224	6	21	,	,	PUNCT
can-224	6	22	strong	strong	ADJ
can-224	6	23	effi	effi	PROPN
can-224	6	24	cacy	cacy	NOUN
can-224	6	25	,	,	PUNCT
can-224	6	26	and	and	CCONJ
can-224	6	27	the	the	DET
can-224	6	28	advantages	advantage	NOUN
can-224	6	29	of	of	ADP
can-224	6	30	small	small	ADJ
can-224	6	31	drug	drug	NOUN
can-224	6	32	response	response	NOUN
can-224	6	33	.	.	PUNCT
can-224	7	1	nano	nano	NOUN
can-224	7	2	-	-	PUNCT
can-224	7	3	materials	material	NOUN
can-224	7	4	,	,	PUNCT
can-224	7	5	the	the	DET
can-224	7	6	specific	specific	ADJ
can-224	7	7	surface	surface	NOUN
can-224	7	8	area	area	NOUN
can-224	7	9	,	,	PUNCT
can-224	7	10	surface	surface	NOUN
can-224	7	11	activity	activity	NOUN
can-224	7	12	,	,	PUNCT
can-224	7	13	high	high	ADJ
can-224	7	14	catalytic	catalytic	ADJ
can-224	7	15	efficiency	efficiency	NOUN
can-224	7	16	,	,	PUNCT
can-224	7	17	surface	surface	VERB
can-224	7	18	active	active	ADJ
can-224	7	19	center	center	NOUN
can-224	7	20	,	,	PUNCT
can-224	7	21	adsorption	adsorption	NOUN
can-224	7	22	capacity	capacity	NOUN
can-224	7	23	and	and	CCONJ
can-224	7	24	other	other	ADJ
can-224	7	25	characteristics	characteristic	NOUN
can-224	7	26	,	,	PUNCT
can-224	7	27	which	which	PRON
can-224	7	28	has	have	VERB
can-224	7	29	many	many	ADJ
can-224	7	30	excellent	excellent	ADJ
can-224	7	31	features	feature	NOUN
can-224	7	32	and	and	CCONJ
can-224	7	33	new	new	ADJ
can-224	7	34	features	feature	NOUN
can-224	7	35	.	.	PUNCT
can-224	8	1	keywords	keyword	NOUN
can-224	8	2	:	:	PUNCT
can-224	8	3	nano	nano	NOUN
can-224	8	4	drug	drug	NOUN
can-224	8	5	carrier	carrier	NOUN
can-224	8	6	;	;	PUNCT
can-224	8	7	nano	nano	NOUN
can-224	8	8	biotechnology	biotechnology	NOUN
can-224	8	9	;	;	PUNCT
can-224	8	10	nanoparticles	nanoparticle	NOUN
can-224	8	11	1	1	NUM
can-224	8	12	.	.	X
can-224	8	13	introduction	introduction	NOUN
can-224	8	14	the	the	DET
can-224	8	15	route	route	NOUN
can-224	8	16	of	of	ADP
can-224	8	17	administration	administration	NOUN
can-224	8	18	is	be	AUX
can-224	8	19	the	the	DET
can-224	8	20	direction	direction	NOUN
can-224	8	21	of	of	ADP
can-224	8	22	the	the	DET
can-224	8	23	drug	drug	NOUN
can-224	8	24	preparation	preparation	NOUN
can-224	8	25	.	.	PUNCT
can-224	9	1	oral	oral	ADJ
can-224	9	2	administration	administration	NOUN
can-224	9	3	is	be	AUX
can-224	9	4	the	the	DET
can-224	9	5	key	key	NOUN
can-224	9	6	to	to	ADP
can-224	9	7	the	the	DET
can-224	9	8	fi	fi	NOUN
can-224	9	9	rst	rst	PROPN
can-224	9	10	eff	eff	PROPN
can-224	9	11	ect	ect	PROPN
can-224	9	12	.	.	PUNCT
can-224	10	1	the	the	DET
can-224	10	2	first	first	ADJ
can-224	10	3	effect	effect	NOUN
can-224	10	4	affects	affect	VERB
can-224	10	5	the	the	DET
can-224	10	6	role	role	NOUN
can-224	10	7	of	of	ADP
can-224	10	8	drugs	drug	NOUN
can-224	10	9	,	,	PUNCT
can-224	10	10	such	such	ADJ
can-224	10	11	as	as	ADP
can-224	10	12	proteins	protein	NOUN
can-224	10	13	,	,	PUNCT
can-224	10	14	peptide	peptide	ADJ
can-224	10	15	drugs	drug	NOUN
can-224	10	16	and	and	CCONJ
can-224	10	17	so	so	ADV
can-224	10	18	on	on	ADV
can-224	10	19	.	.	PUNCT
can-224	11	1	the	the	DET
can-224	11	2	effects	effect	NOUN
can-224	11	3	of	of	ADP
can-224	11	4	drugs	drug	NOUN
can-224	11	5	are	be	AUX
can-224	11	6	usually	usually	ADV
can-224	11	7	targeted	target	VERB
can-224	11	8	to	to	ADP
can-224	11	9	human	human	ADJ
can-224	11	10	organs	organ	NOUN
can-224	11	11	and	and	CCONJ
can-224	11	12	tissue	tissue	NOUN
can-224	11	13	-	-	PUNCT
can-224	11	14	specifi	specifi	PROPN
can-224	11	15	c	c	PROPN
can-224	11	16	specifi	specifi	PROPN
can-224	11	17	c	c	PROPN
can-224	11	18	structures	structure	NOUN
can-224	11	19	such	such	ADJ
can-224	11	20	as	as	ADP
can-224	11	21	human	human	ADJ
can-224	11	22	immune	immune	ADJ
can-224	11	23	system	system	NOUN
can-224	11	24	,	,	PUNCT
can-224	11	25	reticuloendothelial	reticuloendothelial	NOUN
can-224	11	26	,	,	PUNCT
can-224	11	27	and	and	CCONJ
can-224	11	28	blood	blood	NOUN
can-224	11	29	-	-	PUNCT
can-224	11	30	brain	brain	NOUN
can-224	11	31	barrier	barrier	NOUN
can-224	11	32	transport	transport	NOUN
can-224	11	33	.	.	PUNCT
can-224	12	1	on	on	ADP
can-224	12	2	the	the	DET
can-224	12	3	one	one	NUM
can-224	12	4	hand	hand	NOUN
can-224	12	5	,	,	PUNCT
can-224	12	6	the	the	DET
can-224	12	7	body	body	NOUN
can-224	12	8	's	's	PART
can-224	12	9	self	self	NOUN
can-224	12	10	-	-	PUNCT
can-224	12	11	protection	protection	NOUN
can-224	12	12	system	system	NOUN
can-224	12	13	is	be	AUX
can-224	12	14	used	use	VERB
can-224	12	15	for	for	SCONJ
can-224	12	16	macromolecular	macromolecular	ADJ
can-224	12	17	drug	drug	NOUN
can-224	12	18	eff	eff	PROPN
can-224	12	19	ects	ect	VERB
can-224	12	20	to	to	PART
can-224	12	21	reach	reach	VERB
can-224	12	22	the	the	DET
can-224	12	23	lesion	lesion	NOUN
can-224	12	24	's	's	PART
can-224	12	25	ability	ability	NOUN
can-224	12	26	.	.	PUNCT
can-224	13	1	for	for	ADP
can-224	13	2	example	example	NOUN
can-224	13	3	,	,	PUNCT
can-224	13	4	a	a	DET
can-224	13	5	normal	normal	ADJ
can-224	13	6	body	body	NOUN
can-224	13	7	,	,	PUNCT
can-224	13	8	blood	blood	NOUN
can-224	13	9	brain	brain	NOUN
can-224	13	10	barrier	barrier	NOUN
can-224	13	11	,	,	PUNCT
can-224	13	12	the	the	DET
can-224	13	13	general	general	ADJ
can-224	13	14	monoamine	monoamine	NOUN
can-224	13	15	in	in	ADP
can-224	13	16	the	the	DET
can-224	13	17	central	central	ADJ
can-224	13	18	nervous	nervous	ADJ
can-224	13	19	system	system	NOUN
can-224	13	20	can	can	AUX
can-224	13	21	not	not	PART
can-224	13	22	pass	pass	VERB
can-224	13	23	.	.	PUNCT
can-224	14	1	on	on	ADP
can-224	14	2	the	the	DET
can-224	14	3	other	other	ADJ
can-224	14	4	hand	hand	NOUN
can-224	14	5	,	,	PUNCT
can-224	14	6	the	the	DET
can-224	14	7	drug	drug	NOUN
can-224	14	8	can	can	AUX
can-224	14	9	not	not	PART
can-224	14	10	be	be	AUX
can-224	14	11	applied	apply	VERB
can-224	14	12	directly	directly	ADV
can-224	14	13	,	,	PUNCT
can-224	14	14	but	but	CCONJ
can-224	14	15	must	must	AUX
can-224	14	16	be	be	AUX
can-224	14	17	carried	carry	VERB
can-224	14	18	out	out	ADP
can-224	14	19	by	by	ADP
can-224	14	20	certain	certain	ADJ
can-224	14	21	reagents	reagent	NOUN
can-224	14	22	and	and	CCONJ
can-224	14	23	mainly	mainly	ADV
can-224	14	24	hinders	hinder	VERB
can-224	14	25	the	the	DET
can-224	14	26	application	application	NOUN
can-224	14	27	of	of	ADP
can-224	14	28	the	the	DET
can-224	14	29	drug	drug	NOUN
can-224	14	30	in	in	ADP
can-224	14	31	the	the	DET
can-224	14	32	drug	drug	NOUN
can-224	14	33	with	with	ADP
can-224	14	34	greater	great	ADJ
can-224	14	35	side	side	NOUN
can-224	14	36	eff	eff	PROPN
can-224	14	37	ects	ect	NOUN
can-224	14	38	and	and	CCONJ
can-224	14	39	the	the	DET
can-224	14	40	physical	physical	ADJ
can-224	14	41	properties	property	NOUN
can-224	14	42	of	of	ADP
can-224	14	43	the	the	DET
can-224	14	44	drug	drug	NOUN
can-224	14	45	itself	itself	PRON
can-224	14	46	(	(	PUNCT
can-224	14	47	e.g.	e.g.	ADV
can-224	14	48	poorly	poorly	ADV
can-224	14	49	soluble	soluble	ADJ
can-224	14	50	drugs	drug	NOUN
can-224	14	51	)	)	PUNCT
can-224	14	52	.	.	PUNCT
can-224	15	1	overcoming	overcome	VERB
can-224	15	2	the	the	DET
can-224	15	3	obstruction	obstruction	NOUN
can-224	15	4	of	of	ADP
can-224	15	5	the	the	DET
can-224	15	6	human	human	PROPN
can-224	15	7	health	health	PROPN
can-224	15	8	drug	drug	PROPN
can-224	15	9	administration	administration	NOUN
can-224	15	10	is	be	AUX
can-224	15	11	the	the	DET
can-224	15	12	direction	direction	NOUN
can-224	15	13	of	of	ADP
can-224	15	14	modern	modern	ADJ
can-224	15	15	medicine	medicine	NOUN
can-224	15	16	research	research	NOUN
can-224	15	17	to	to	PART
can-224	15	18	improve	improve	VERB
can-224	15	19	the	the	DET
can-224	15	20	physical	physical	ADJ
can-224	15	21	properties	property	NOUN
can-224	15	22	of	of	ADP
can-224	15	23	drugs	drug	NOUN
can-224	15	24	(	(	PUNCT
can-224	15	25	solubility	solubility	NOUN
can-224	15	26	,	,	PUNCT
can-224	15	27	dissolution	dissolution	NOUN
can-224	15	28	rate	rate	NOUN
can-224	15	29	,	,	PUNCT
can-224	15	30	etc	etc	X
can-224	15	31	.	.	X
can-224	15	32	)	)	PUNCT
can-224	15	33	to	to	PART
can-224	15	34	reduce	reduce	VERB
can-224	15	35	the	the	DET
can-224	15	36	adverse	adverse	ADJ
can-224	15	37	eff	eff	PROPN
can-224	15	38	ects	ect	NOUN
can-224	15	39	of	of	ADP
can-224	15	40	drugs	drug	NOUN
can-224	15	41	,	,	PUNCT
can-224	15	42	for	for	ADP
can-224	15	43	enhanced	enhanced	ADJ
can-224	15	44	performance	performance	NOUN
can-224	15	45	of	of	ADP
can-224	15	46	drugs	drug	NOUN
can-224	15	47	,	,	PUNCT
can-224	15	48	increased	increase	VERB
can-224	15	49	bioavailability	bioavailability	NOUN
can-224	15	50	,	,	PUNCT
can-224	15	51	there	there	PRON
can-224	15	52	are	be	VERB
can-224	15	53	also	also	ADV
can-224	15	54	ways	way	NOUN
can-224	15	55	to	to	PART
can-224	15	56	solve	solve	VERB
can-224	15	57	this	this	DET
can-224	15	58	problem	problem	NOUN
can-224	15	59	by	by	ADP
can-224	15	60	combining	combine	VERB
can-224	15	61	nanotechnology	nanotechnology	NOUN
can-224	15	62	with	with	ADP
can-224	15	63	biomedicine	biomedicine	NOUN
can-224	15	64	.	.	PUNCT
can-224	16	1	traditional	traditional	ADJ
can-224	16	2	pharmacy	pharmacy	NOUN
can-224	16	3	,	,	PUNCT
can-224	16	4	pharmacology	pharmacology	NOUN
can-224	16	5	and	and	CCONJ
can-224	16	6	other	other	ADJ
can-224	16	7	multidisciplinary	multidisciplinary	ADJ
can-224	16	8	and	and	CCONJ
can-224	16	9	nano	nano	NOUN
can-224	16	10	medical	medical	ADJ
can-224	16	11	combination	combination	NOUN
can-224	16	12	of	of	ADP
can-224	16	13	modern	modern	ADJ
can-224	16	14	nanotechnology	nanotechnology	NOUN
can-224	16	15	products	product	NOUN
can-224	16	16	.	.	PUNCT
can-224	17	1	according	accord	VERB
can-224	17	2	to	to	ADP
can-224	17	3	the	the	DET
can-224	17	4	american	american	PROPN
can-224	17	5	health	health	PROPN
can-224	17	6	association	association	PROPN
can-224	17	7	,	,	PUNCT
can-224	17	8	the	the	DET
can-224	17	9	use	use	NOUN
can-224	17	10	of	of	ADP
can-224	17	11	nanotechnology	nanotechnology	NOUN
can-224	17	12	to	to	PART
can-224	17	13	control	control	VERB
can-224	17	14	drug	drug	PROPN
can-224	17	15	effi	effi	PROPN
can-224	17	16	cacy	cacy	PROPN
can-224	17	17	,	,	PUNCT
can-224	17	18	diagnosis	diagnosis	NOUN
can-224	17	19	,	,	PUNCT
can-224	17	20	monitoring	monitoring	NOUN
can-224	17	21	and	and	CCONJ
can-224	17	22	nanotechnology	nanotechnology	NOUN
can-224	17	23	of	of	ADP
can-224	17	24	biological	biological	ADJ
can-224	17	25	systems	system	NOUN
can-224	17	26	.	.	PUNCT
can-224	18	1	drug	drug	NOUN
can-224	18	2	formulations	formulation	NOUN
can-224	18	3	that	that	PRON
can-224	18	4	explore	explore	VERB
can-224	18	5	the	the	DET
can-224	18	6	transport	transport	NOUN
can-224	18	7	and	and	CCONJ
can-224	18	8	targeting	target	VERB
can-224	18	9	characteristics	characteristic	NOUN
can-224	18	10	of	of	ADP
can-224	18	11	the	the	DET
can-224	18	12	theoretical	theoretical	ADJ
can-224	18	13	formula	formula	NOUN
can-224	18	14	and	and	CCONJ
can-224	18	15	diagnostic	diagnostic	ADJ
can-224	18	16	mode	mode	NOUN
can-224	18	17	of	of	ADP
can-224	18	18	effi	effi	PROPN
can-224	18	19	cacy	cacy	NOUN
can-224	18	20	of	of	ADP
can-224	18	21	the	the	DET
can-224	18	22	nano	nano	NOUN
can-224	18	23	pharmaceutical	pharmaceutical	NOUN
can-224	18	24	problem	problem	NOUN
can-224	18	25	at	at	ADP
can-224	18	26	the	the	DET
can-224	18	27	forefront	forefront	NOUN
can-224	18	28	,	,	PUNCT
can-224	18	29	mainly	mainly	ADV
can-224	18	30	including	include	VERB
can-224	18	31	precise	precise	ADJ
can-224	18	32	and	and	CCONJ
can-224	18	33	specifi	specifi	PROPN
can-224	18	34	c	c	PROPN
can-224	18	35	clinical	clinical	ADJ
can-224	18	36	pathology	pathology	NOUN
can-224	18	37	to	to	PART
can-224	18	38	determine	determine	VERB
can-224	18	39	the	the	DET
can-224	18	40	location	location	NOUN
can-224	18	41	of	of	ADP
can-224	18	42	the	the	DET
can-224	18	43	environment	environment	NOUN
can-224	18	44	associated	associate	VERB
can-224	18	45	with	with	ADP
can-224	18	46	the	the	DET
can-224	18	47	lesion	lesion	NOUN
can-224	18	48	and	and	CCONJ
can-224	18	49	at	at	ADP
can-224	18	50	the	the	DET
can-224	18	51	same	same	ADJ
can-224	18	52	time	time	NOUN
can-224	18	53	the	the	DET
can-224	18	54	risk	risk	NOUN
can-224	18	55	of	of	ADP
can-224	18	56	adverse	adverse	ADJ
can-224	18	57	eff	eff	PROPN
can-224	18	58	ects	ect	VERB
can-224	18	59	to	to	PART
can-224	18	60	select	select	VERB
can-224	18	61	the	the	DET
can-224	18	62	appropriate	appropriate	ADJ
can-224	18	63	nano	nano	NOUN
can-224	18	64	-	-	PUNCT
can-224	18	65	carrier	carrier	NOUN
can-224	18	66	to	to	PART
can-224	18	67	meet	meet	VERB
can-224	18	68	specifi	specifi	PROPN
can-224	18	69	c	c	PROPN
can-224	18	70	requirements	requirement	NOUN
can-224	18	71	.	.	PUNCT
can-224	19	1	therefore	therefore	ADV
can-224	19	2	,	,	PUNCT
can-224	19	3	they	they	PRON
can-224	19	4	need	need	VERB
can-224	19	5	to	to	PART
can-224	19	6	fi	fi	VERB
can-224	19	7	nd	nd	ADV
can-224	19	8	a	a	DET
can-224	19	9	way	way	NOUN
can-224	19	10	to	to	PART
can-224	19	11	mass	mass	VERB
can-224	19	12	production	production	NOUN
can-224	19	13	of	of	ADP
can-224	19	14	nano	nano	NOUN
can-224	19	15	-	-	PUNCT
can-224	19	16	drug	drug	NOUN
can-224	19	17	convenience	convenience	NOUN
can-224	19	18	.	.	PUNCT
can-224	20	1	2	2	X
can-224	20	2	.	.	X
can-224	20	3	introduction	introduction	NOUN
can-224	20	4	2.1	2.1	NUM
can-224	20	5	.	.	PUNCT
can-224	21	1	objective	objective	ADJ
can-224	21	2	and	and	CCONJ
can-224	21	3	signifi	signifi	NOUN
can-224	21	4	cance	cance	NOUN
can-224	21	5	of	of	ADP
can-224	21	6	nano	nano	NOUN
can-224	21	7	-	-	PUNCT
can-224	21	8	drug	drug	NOUN
can-224	21	9	carrier	carrier	NOUN
can-224	21	10	research	research	NOUN
can-224	21	11	nano	nano	NOUN
can-224	21	12	-	-	PUNCT
can-224	21	13	drug	drug	NOUN
can-224	21	14	carriers	carrier	NOUN
can-224	21	15	are	be	AUX
can-224	21	16	usually	usually	ADV
can-224	21	17	synthesized	synthesize	VERB
can-224	21	18	from	from	ADP
can-224	21	19	natural	natural	ADJ
can-224	21	20	or	or	CCONJ
can-224	21	21	polymeric	polymeric	ADJ
can-224	21	22	materials	material	NOUN
can-224	21	23	at	at	ADP
can-224	21	24	a	a	DET
can-224	21	25	size	size	NOUN
can-224	21	26	of	of	ADP
can-224	21	27	10	10	NUM
can-224	21	28	-	-	SYM
can-224	21	29	1000	1000	NUM
can-224	21	30	nm	nm	NOUN
can-224	21	31	because	because	SCONJ
can-224	21	32	of	of	ADP
can-224	21	33	their	their	PRON
can-224	21	34	targeted	target	VERB
can-224	21	35	and	and	CCONJ
can-224	21	36	slow	slow	ADJ
can-224	21	37	release	release	NOUN
can-224	21	38	,	,	PUNCT
can-224	21	39	so	so	CCONJ
can-224	21	40	the	the	DET
can-224	21	41	carrier	carrier	NOUN
can-224	21	42	material	material	NOUN
can-224	21	43	has	have	VERB
can-224	21	44	other	other	ADJ
can-224	21	45	signifi	signifi	NOUN
can-224	21	46	ca	can	AUX
can-224	21	47	nt	not	PART
can-224	21	48	advantages	advantage	NOUN
can-224	21	49	of	of	ADP
can-224	21	50	biocompatible	biocompatible	ADJ
can-224	21	51	biodegradability	biodegradability	NOUN
can-224	21	52	,	,	PUNCT
can-224	21	53	which	which	PRON
can-224	21	54	has	have	AUX
can-224	21	55	been	be	AUX
can-224	21	56	widely	widely	ADV
can-224	21	57	used	use	VERB
can-224	21	58	in	in	ADP
can-224	21	59	pharmaceuticals	pharmaceutical	NOUN
can-224	21	60	preparation	preparation	NOUN
can-224	21	61	development	development	NOUN
can-224	21	62	.	.	PUNCT
can-224	22	1	the	the	DET
can-224	22	2	nanoparticles	nanoparticle	NOUN
can-224	22	3	are	be	AUX
can-224	22	4	used	use	VERB
can-224	22	5	as	as	ADP
can-224	22	6	drug	drug	NOUN
can-224	22	7	carriers	carrier	NOUN
can-224	22	8	in	in	ADP
can-224	22	9	which	which	PRON
can-224	22	10	the	the	DET
can-224	22	11	therapeutic	therapeutic	ADJ
can-224	22	12	drug	drug	NOUN
can-224	22	13	is	be	AUX
can-224	22	14	encapsulated	encapsulate	VERB
can-224	22	15	into	into	ADP
can-224	22	16	the	the	DET
can-224	22	17	nanoparticles	nanoparticle	NOUN
can-224	22	18	or	or	CCONJ
can-224	22	19	adsorbed	adsorb	VERB
can-224	22	20	on	on	ADP
can-224	22	21	the	the	DET
can-224	22	22	surface	surface	NOUN
can-224	22	23	thereof	thereof	ADV
can-224	22	24	by	by	ADP
can-224	22	25	means	mean	NOUN
can-224	22	26	of	of	ADP
can-224	22	27	jianping	jianping	NOUN
can-224	22	28	wu	wu	PROPN
can-224	22	29	,	,	PUNCT
can-224	22	30	et	et	PROPN
can-224	22	31	al	al	PROPN
can-224	22	32	13	13	NUM
can-224	22	33	targeted	target	VERB
can-224	22	34	molecules	molecule	NOUN
can-224	22	35	,	,	PUNCT
can-224	22	36	for	for	ADP
can-224	22	37	effi	effi	PROPN
can-224	22	38	cient	cient	PROPN
can-224	22	39	delivery	delivery	NOUN
can-224	22	40	and	and	CCONJ
can-224	22	41	gene	gene	NOUN
can-224	22	42	therapy	therapy	NOUN
can-224	22	43	.	.	PUNCT
can-224	23	1	nano	nano	NOUN
can-224	23	2	-	-	PUNCT
can-224	23	3	carrier	carrier	NOUN
can-224	23	4	technology	technology	NOUN
can-224	23	5	is	be	AUX
can-224	23	6	an	an	DET
can-224	23	7	important	important	ADJ
can-224	23	8	development	development	NOUN
can-224	23	9	of	of	ADP
can-224	23	10	nano	nano	NOUN
can-224	23	11	-	-	PUNCT
can-224	23	12	biotechnology	biotechnology	NOUN
can-224	23	13	[	[	NOUN
can-224	23	14	1	1	NUM
can-224	23	15	]	]	PUNCT
can-224	23	16	.	.	PUNCT
can-224	24	1	nanotechnology	nanotechnology	NOUN
can-224	24	2	and	and	CCONJ
can-224	24	3	nanomaterials	nanomaterial	NOUN
can-224	24	4	will	will	AUX
can-224	24	5	be	be	AUX
can-224	24	6	applied	apply	VERB
can-224	24	7	to	to	ADP
can-224	24	8	the	the	DET
can-224	24	9	pharmaceutical	pharmaceutical	ADJ
can-224	24	10	fi	fi	NOUN
can-224	24	11	eld	eld	NOUN
can-224	24	12	to	to	PART
can-224	24	13	form	form	VERB
can-224	24	14	nano	nano	NOUN
can-224	24	15	complex	complex	ADJ
can-224	24	16	carriers	carrier	NOUN
can-224	24	17	,	,	PUNCT
can-224	24	18	in	in	ADP
can-224	24	19	vivo	vivo	ADJ
can-224	24	20	drugs	drug	NOUN
can-224	24	21	that	that	PRON
can-224	24	22	carry	carry	VERB
can-224	24	23	nanoparticles	nanoparticle	NOUN
can-224	24	24	of	of	ADP
can-224	24	25	drugs	drug	NOUN
can-224	24	26	or	or	CCONJ
can-224	24	27	embedded	embed	VERB
can-224	24	28	in	in	ADP
can-224	24	29	their	their	PRON
can-224	24	30	surface	surface	NOUN
can-224	24	31	after	after	ADP
can-224	24	32	adsorbing	adsorb	VERB
can-224	24	33	nanoparticles	nanoparticle	NOUN
can-224	24	34	,	,	PUNCT
can-224	24	35	to	to	PART
can-224	24	36	form	form	VERB
can-224	24	37	a	a	DET
can-224	24	38	stable	stable	ADJ
can-224	24	39	nano	nano	NOUN
can-224	24	40	sized	size	VERB
can-224	24	41	drug	drug	NOUN
can-224	24	42	delivery	delivery	NOUN
can-224	24	43	system	system	NOUN
can-224	24	44	.	.	PUNCT
can-224	25	1	nano	nano	NOUN
can-224	25	2	-	-	PUNCT
can-224	25	3	carrier	carrier	NOUN
can-224	25	4	drug	drug	NOUN
can-224	25	5	delivery	delivery	NOUN
can-224	25	6	methods	method	NOUN
can-224	25	7	are	be	AUX
can-224	25	8	hydrophobic	hydrophobic	ADJ
can-224	25	9	,	,	PUNCT
can-224	25	10	electrostatic	electrostatic	ADJ
can-224	25	11	,	,	PUNCT
can-224	25	12	hydrogen	hydrogen	NOUN
can-224	25	13	bonding	bonding	NOUN
can-224	25	14	,	,	PUNCT
can-224	25	15	and	and	CCONJ
can-224	25	16	covalent	covalent	ADJ
can-224	25	17	role	role	NOUN
can-224	25	18	.	.	PUNCT
can-224	26	1	in	in	ADP
can-224	26	2	the	the	DET
can-224	26	3	fi	fi	NOUN
can-224	26	4	eld	eld	NOUN
can-224	26	5	of	of	ADP
can-224	26	6	drug	drug	NOUN
can-224	26	7	discovery	discovery	NOUN
can-224	26	8	.	.	PUNCT
can-224	27	1	which	which	PRON
can-224	27	2	has	have	VERB
can-224	27	3	the	the	DET
can-224	27	4	following	following	ADJ
can-224	27	5	advantages	advantage	NOUN
can-224	27	6	:	:	PUNCT
can-224	27	7	(	(	PUNCT
can-224	27	8	a	a	X
can-224	27	9	)	)	PUNCT
can-224	27	10	enhance	enhance	VERB
can-224	27	11	the	the	DET
can-224	27	12	dissolution	dissolution	NOUN
can-224	27	13	of	of	ADP
can-224	27	14	insoluble	insoluble	ADJ
can-224	27	15	drugs	drug	NOUN
can-224	27	16	.	.	PUNCT
can-224	28	1	the	the	DET
can-224	28	2	hydrophobic	hydrophobic	NOUN
can-224	28	3	drug	drug	NOUN
can-224	28	4	will	will	AUX
can-224	28	5	be	be	AUX
can-224	28	6	precipitated	precipitate	VERB
can-224	28	7	in	in	ADP
can-224	28	8	the	the	DET
can-224	28	9	blood	blood	NOUN
can-224	28	10	circulation	circulation	NOUN
can-224	28	11	and	and	CCONJ
can-224	28	12	the	the	DET
can-224	28	13	drug	drug	NOUN
can-224	28	14	is	be	AUX
can-224	28	15	diffi	diffi	ADJ
can-224	28	16	cult	cult	NOUN
can-224	28	17	to	to	PART
can-224	28	18	reach	reach	VERB
can-224	28	19	the	the	DET
can-224	28	20	lesion	lesion	NOUN
can-224	28	21	site	site	NOUN
can-224	28	22	.	.	PUNCT
can-224	29	1	therefore	therefore	ADV
can-224	29	2	,	,	PUNCT
can-224	29	3	the	the	DET
can-224	29	4	hydrophobic	hydrophobic	NOUN
can-224	29	5	drug	drug	NOUN
can-224	29	6	will	will	AUX
can-224	29	7	be	be	AUX
can-224	29	8	packaged	package	VERB
can-224	29	9	in	in	ADP
can-224	29	10	the	the	DET
can-224	29	11	nano	nano	NOUN
can-224	29	12	-	-	PUNCT
can-224	29	13	drug	drug	NOUN
can-224	29	14	carrier	carrier	NOUN
can-224	29	15	,	,	PUNCT
can-224	29	16	and	and	CCONJ
can-224	29	17	the	the	DET
can-224	29	18	outer	outer	ADJ
can-224	29	19	layer	layer	NOUN
can-224	29	20	of	of	ADP
can-224	29	21	the	the	DET
can-224	29	22	nano	nano	NOUN
can-224	29	23	carrier	carrier	NOUN
can-224	29	24	is	be	AUX
can-224	29	25	usually	usually	ADV
can-224	29	26	a	a	DET
can-224	29	27	hydrophilic	hydrophilic	ADJ
can-224	29	28	layer	layer	NOUN
can-224	29	29	,	,	PUNCT
can-224	29	30	which	which	PRON
can-224	29	31	can	can	AUX
can-224	29	32	better	well	ADV
can-224	29	33	avoid	avoid	VERB
can-224	29	34	the	the	DET
can-224	29	35	drug	drug	NOUN
can-224	29	36	aggregation	aggregation	NOUN
can-224	29	37	and	and	CCONJ
can-224	29	38	precipitation	precipitation	NOUN
can-224	29	39	,	,	PUNCT
can-224	29	40	thereby	thereby	ADV
can-224	29	41	ultimately	ultimately	ADV
can-224	29	42	enhancing	enhance	VERB
can-224	29	43	the	the	DET
can-224	29	44	solubility	solubility	NOUN
can-224	29	45	of	of	ADP
can-224	29	46	the	the	DET
can-224	29	47	drug	drug	NOUN
can-224	29	48	.	.	PUNCT
can-224	30	1	(	(	PUNCT
can-224	30	2	b	b	X
can-224	30	3	)	)	PUNCT
can-224	30	4	to	to	PART
can-224	30	5	prevent	prevent	VERB
can-224	30	6	drug	drug	NOUN
can-224	30	7	degradation	degradation	NOUN
can-224	30	8	,	,	PUNCT
can-224	30	9	improve	improve	VERB
can-224	30	10	the	the	DET
can-224	30	11	stability	stability	NOUN
can-224	30	12	of	of	ADP
can-224	30	13	the	the	DET
can-224	30	14	drug	drug	NOUN
can-224	30	15	,	,	PUNCT
can-224	30	16	for	for	ADP
can-224	30	17	the	the	DET
can-224	30	18	biological	biological	ADJ
can-224	30	19	activity	activity	NOUN
can-224	30	20	of	of	ADP
can-224	30	21	drugs	drug	NOUN
can-224	30	22	,	,	PUNCT
can-224	30	23	such	such	ADJ
can-224	30	24	as	as	ADP
can-224	30	25	easily	easily	ADV
can-224	30	26	degraded	degrade	VERB
can-224	30	27	in	in	ADP
can-224	30	28	the	the	DET
can-224	30	29	human	human	ADJ
can-224	30	30	camptothecin	camptothecin	NOUN
can-224	30	31	,	,	PUNCT
can-224	30	32	and	and	CCONJ
can-224	30	33	therefore	therefore	ADV
can-224	30	34	lose	lose	VERB
can-224	30	35	the	the	DET
can-224	30	36	drug	drug	NOUN
can-224	30	37	eff	eff	PROPN
can-224	30	38	ect	ect	PROPN
can-224	30	39	.	.	PUNCT
can-224	31	1	and	and	CCONJ
can-224	31	2	the	the	DET
can-224	31	3	use	use	NOUN
can-224	31	4	of	of	ADP
can-224	31	5	nano	nano	NOUN
can-224	31	6	-	-	PUNCT
can-224	31	7	drug	drug	NOUN
can-224	31	8	carrier	carrier	NOUN
can-224	31	9	can	can	AUX
can-224	31	10	be	be	AUX
can-224	31	11	wrapped	wrap	VERB
can-224	31	12	to	to	PART
can-224	31	13	achieve	achieve	VERB
can-224	31	14	the	the	DET
can-224	31	15	purpose	purpose	NOUN
can-224	31	16	of	of	ADP
can-224	31	17	avoiding	avoid	VERB
can-224	31	18	its	its	PRON
can-224	31	19	degradation	degradation	NOUN
can-224	31	20	.	.	PUNCT
can-224	32	1	(	(	PUNCT
can-224	32	2	c	c	X
can-224	32	3	)	)	PUNCT
can-224	32	4	improving	improve	VERB
can-224	32	5	the	the	DET
can-224	32	6	properties	property	NOUN
can-224	32	7	of	of	ADP
can-224	32	8	the	the	DET
can-224	32	9	drug	drug	NOUN
can-224	32	10	dispersion	dispersion	NOUN
can-224	32	11	in	in	ADP
can-224	32	12	the	the	DET
can-224	32	13	body	body	NOUN
can-224	32	14	to	to	PART
can-224	32	15	reduce	reduce	VERB
can-224	32	16	or	or	CCONJ
can-224	32	17	eliminate	eliminate	VERB
can-224	32	18	tissue	tissue	NOUN
can-224	32	19	damage	damage	NOUN
can-224	32	20	caused	cause	VERB
can-224	32	21	by	by	ADP
can-224	32	22	leakage	leakage	NOUN
can-224	32	23	of	of	ADP
can-224	32	24	the	the	DET
can-224	32	25	resulting	result	VERB
can-224	32	26	drug	drug	NOUN
can-224	32	27	.	.	PUNCT
can-224	33	1	after	after	ADP
can-224	33	2	this	this	PRON
can-224	33	3	,	,	PUNCT
can-224	33	4	by	by	ADP
can-224	33	5	the	the	DET
can-224	33	6	reticulate	reticulate	ADJ
can-224	33	7	endothelial	endothelial	ADJ
can-224	33	8	system	system	NOUN
can-224	33	9	of	of	ADP
can-224	33	10	phagocytic	phagocytic	ADJ
can-224	33	11	nano	nano	NOUN
can-224	33	12	into	into	ADP
can-224	33	13	the	the	DET
can-224	33	14	human	human	ADJ
can-224	33	15	body	body	NOUN
can-224	33	16	,	,	PUNCT
can-224	33	17	you	you	PRON
can-224	33	18	can	can	AUX
can-224	33	19	quickly	quickly	ADV
can-224	33	20	phagocytic	phagocytic	ADJ
can-224	33	21	cells	cell	NOUN
can-224	33	22	in	in	ADP
can-224	33	23	the	the	DET
can-224	33	24	region	region	NOUN
can-224	33	25	.	.	PUNCT
can-224	34	1	for	for	ADP
can-224	34	2	example	example	NOUN
can-224	34	3	,	,	PUNCT
can-224	34	4	doxorubicin	doxorubicin	PROPN
can-224	34	5	can	can	AUX
can-224	34	6	not	not	PART
can-224	34	7	only	only	ADV
can-224	34	8	destroy	destroy	VERB
can-224	34	9	cancer	cancer	NOUN
can-224	34	10	cells	cell	NOUN
can-224	34	11	,	,	PUNCT
can-224	34	12	but	but	CCONJ
can-224	34	13	also	also	ADV
can-224	34	14	greatly	greatly	ADV
can-224	34	15	damage	damage	VERB
can-224	34	16	the	the	DET
can-224	34	17	normal	normal	ADJ
can-224	34	18	cells	cell	NOUN
can-224	34	19	,	,	PUNCT
can-224	34	20	nano	nano	NOUN
can-224	34	21	-	-	PUNCT
can-224	34	22	drug	drug	NOUN
can-224	34	23	carrier	carrier	NOUN
can-224	34	24	can	can	AUX
can-224	34	25	focus	focus	VERB
can-224	34	26	on	on	ADP
can-224	34	27	the	the	DET
can-224	34	28	lesion	lesion	NOUN
can-224	34	29	site	site	NOUN
can-224	34	30	(	(	PUNCT
can-224	34	31	targeted	target	VERB
can-224	34	32	release	release	NOUN
can-224	34	33	)	)	PUNCT
can-224	34	34	,	,	PUNCT
can-224	34	35	so	so	SCONJ
can-224	34	36	that	that	PRON
can-224	34	37	can	can	AUX
can-224	34	38	reduce	reduce	VERB
can-224	34	39	the	the	DET
can-224	34	40	damage	damage	NOUN
can-224	34	41	to	to	ADP
can-224	34	42	normal	normal	ADJ
can-224	34	43	tissue	tissue	NOUN
can-224	34	44	.	.	PUNCT
can-224	35	1	(	(	PUNCT
can-224	35	2	d	d	X
can-224	35	3	)	)	PUNCT
can-224	35	4	improving	improve	VERB
can-224	35	5	the	the	DET
can-224	35	6	absorption	absorption	NOUN
can-224	35	7	of	of	ADP
can-224	35	8	drugs	drug	NOUN
can-224	35	9	.	.	PUNCT
can-224	36	1	because	because	SCONJ
can-224	36	2	the	the	DET
can-224	36	3	nano	nano	NOUN
can-224	36	4	-	-	PUNCT
can-224	36	5	drug	drug	NOUN
can-224	36	6	carrier	carrier	NOUN
can-224	36	7	is	be	AUX
can-224	36	8	too	too	ADV
can-224	36	9	dispersed	disperse	VERB
can-224	36	10	,	,	PUNCT
can-224	36	11	the	the	DET
can-224	36	12	surface	surface	NOUN
can-224	36	13	area	area	NOUN
can-224	36	14	and	and	CCONJ
can-224	36	15	the	the	DET
can-224	36	16	surface	surface	NOUN
can-224	36	17	has	have	VERB
can-224	36	18	a	a	DET
can-224	36	19	special	special	ADJ
can-224	36	20	function	function	NOUN
can-224	36	21	,	,	PUNCT
can-224	36	22	which	which	PRON
can-224	36	23	can	can	AUX
can-224	36	24	better	well	ADV
can-224	36	25	improve	improve	VERB
can-224	36	26	the	the	DET
can-224	36	27	drug	drug	NOUN
can-224	36	28	contact	contact	NOUN
can-224	36	29	area	area	NOUN
can-224	36	30	and	and	CCONJ
can-224	36	31	time	time	NOUN
can-224	36	32	,	,	PUNCT
can-224	36	33	in	in	ADP
can-224	36	34	the	the	DET
can-224	36	35	lesion	lesion	NOUN
can-224	36	36	,	,	PUNCT
can-224	36	37	so	so	SCONJ
can-224	36	38	that	that	SCONJ
can-224	36	39	the	the	DET
can-224	36	40	effi	effi	PROPN
can-224	36	41	ciency	ciency	NOUN
can-224	36	42	of	of	ADP
can-224	36	43	the	the	DET
can-224	36	44	drug	drug	NOUN
can-224	36	45	can	can	AUX
can-224	36	46	be	be	AUX
can-224	36	47	improved	improve	VERB
can-224	36	48	.	.	PUNCT
can-224	37	1	(	(	PUNCT
can-224	37	2	e	e	NOUN
can-224	37	3	)	)	PUNCT
can-224	37	4	membrane	membrane	ADJ
can-224	37	5	transduction	transduction	NOUN
can-224	37	6	mechanisms	mechanism	NOUN
can-224	37	7	that	that	PRON
can-224	37	8	enhance	enhance	VERB
can-224	37	9	the	the	DET
can-224	37	10	permeability	permeability	NOUN
can-224	37	11	of	of	ADP
can-224	37	12	drugs	drug	NOUN
can-224	37	13	that	that	PRON
can-224	37	14	are	be	AUX
can-224	37	15	benefi	benefi	PROPN
can-224	37	16	cial	cial	NOUN
can-224	37	17	to	to	ADP
can-224	37	18	some	some	PRON
can-224	37	19	of	of	ADP
can-224	37	20	the	the	DET
can-224	37	21	special	special	ADJ
can-224	37	22	parts	part	NOUN
can-224	37	23	of	of	ADP
can-224	37	24	the	the	DET
can-224	37	25	biofi	biofi	NOUN
can-224	38	1	lm	lm	PROPN
can-224	38	2	.	.	PROPN
can-224	38	3	2.2	2.2	NUM
can-224	39	1	.	.	PUNCT
can-224	39	2	types	type	NOUN
can-224	39	3	and	and	CCONJ
can-224	39	4	characteristics	characteristic	NOUN
can-224	39	5	of	of	ADP
can-224	39	6	nano	nano	NOUN
can-224	39	7	-	-	PUNCT
can-224	39	8	drug	drug	NOUN
can-224	39	9	carriers	carrier	NOUN
can-224	39	10	according	accord	VERB
can-224	39	11	to	to	ADP
can-224	39	12	the	the	DET
can-224	39	13	preparation	preparation	NOUN
can-224	39	14	of	of	ADP
can-224	39	15	nano	nano	NOUN
can-224	39	16	-	-	PUNCT
can-224	39	17	drug	drug	NOUN
can-224	39	18	carrier	carrier	NOUN
can-224	39	19	material	material	NOUN
can-224	39	20	can	can	AUX
can-224	39	21	be	be	AUX
can-224	39	22	divided	divide	VERB
can-224	39	23	into	into	ADP
can-224	39	24	nano	nano	NOUN
can-224	39	25	-	-	PUNCT
can-224	39	26	particles	particle	NOUN
can-224	39	27	,	,	PUNCT
can-224	39	28	nano	nano	NOUN
can-224	39	29	-	-	PUNCT
can-224	39	30	milk	milk	NOUN
can-224	39	31	,	,	PUNCT
can-224	39	32	nanomicelles	nanomicelle	NOUN
can-224	39	33	,	,	PUNCT
can-224	39	34	nano	nano	NOUN
can-224	39	35	-	-	PUNCT
can-224	39	36	suspension	suspension	NOUN
can-224	39	37	,	,	PUNCT
can-224	39	38	and	and	CCONJ
can-224	39	39	drug	drug	NOUN
can-224	39	40	-	-	PUNCT
can-224	39	41	like	like	ADJ
can-224	39	42	body	body	NOUN
can-224	39	43	[	[	X
can-224	39	44	2	2	NUM
can-224	39	45	]	]	PUNCT
can-224	39	46	.	.	PUNCT
can-224	40	1	the	the	DET
can-224	40	2	nanoparticle	nanoparticle	NOUN
can-224	40	3	nanoparticles	nanoparticle	NOUN
can-224	40	4	are	be	AUX
can-224	40	5	solid	solid	ADJ
can-224	40	6	colloidal	colloidal	NOUN
can-224	40	7	particles	particle	NOUN
can-224	40	8	smaller	small	ADJ
can-224	40	9	than	than	ADP
can-224	40	10	the	the	DET
can-224	40	11	lttm	lttm	NOUN
can-224	40	12	polymer	polymer	NOUN
can-224	40	13	colloid	colloid	NOUN
can-224	40	14	drug	drug	NOUN
can-224	40	15	delivery	delivery	NOUN
can-224	40	16	system	system	NOUN
can-224	40	17	[	[	X
can-224	40	18	3	3	NUM
can-224	40	19	]	]	PUNCT
can-224	40	20	.	.	PUNCT
can-224	41	1	is	be	AUX
can-224	41	2	a	a	DET
can-224	41	3	solid	solid	ADJ
can-224	41	4	formed	form	VERB
can-224	41	5	in	in	ADP
can-224	41	6	the	the	DET
can-224	41	7	polymer	polymer	NOUN
can-224	41	8	backbone	backbone	NOUN
can-224	41	9	,	,	PUNCT
can-224	41	10	in	in	ADP
can-224	41	11	which	which	PRON
can-224	41	12	the	the	DET
can-224	41	13	drug	drug	NOUN
can-224	41	14	can	can	AUX
can-224	41	15	be	be	AUX
can-224	41	16	dissolved	dissolve	VERB
can-224	41	17	or	or	CCONJ
can-224	41	18	coated	coat	VERB
can-224	41	19	on	on	ADP
can-224	41	20	a	a	DET
can-224	41	21	solid	solid	ADJ
can-224	41	22	adsorbent	adsorbent	NOUN
can-224	41	23	by	by	ADP
can-224	41	24	preparing	prepare	VERB
can-224	41	25	different	different	ADJ
can-224	41	26	drug	drug	NOUN
can-224	41	27	cladding	cladding	NOUN
can-224	41	28	modules	module	NOUN
can-224	41	29	into	into	ADP
can-224	41	30	nano	nano	NOUN
can-224	41	31	spheres	sphere	NOUN
can-224	41	32	and	and	CCONJ
can-224	41	33	nano	nano	NOUN
can-224	41	34	capsules	capsule	NOUN
can-224	41	35	.	.	PUNCT
can-224	42	1	when	when	SCONJ
can-224	42	2	the	the	DET
can-224	42	3	drug	drug	NOUN
can-224	42	4	is	be	AUX
can-224	42	5	dissolved	dissolve	VERB
can-224	42	6	,	,	PUNCT
can-224	42	7	dispersed	disperse	VERB
can-224	42	8	or	or	CCONJ
can-224	42	9	adsorbed	adsorb	VERB
can-224	42	10	,	,	PUNCT
can-224	42	11	ball	ball	NOUN
can-224	42	12	-	-	PUNCT
can-224	42	13	forming	form	VERB
can-224	42	14	polymer	polymer	NOUN
can-224	42	15	drugs	drug	NOUN
can-224	42	16	are	be	AUX
can-224	42	17	called	call	VERB
can-224	42	18	nano	nano	NOUN
can-224	42	19	spheres	sphere	NOUN
can-224	42	20	;	;	PUNCT
can-224	42	21	nano	nano	NOUN
can-224	42	22	capsules	capsule	NOUN
can-224	42	23	are	be	AUX
can-224	42	24	spherical	spherical	ADJ
can-224	42	25	nanoparticles	nanoparticle	NOUN
can-224	42	26	[	[	X
can-224	42	27	4	4	NUM
can-224	42	28	]	]	PUNCT
can-224	42	29	formed	form	VERB
can-224	42	30	by	by	ADP
can-224	42	31	the	the	DET
can-224	42	32	encapsulation	encapsulation	NOUN
can-224	42	33	of	of	ADP
can-224	42	34	solid	solid	ADJ
can-224	42	35	or	or	CCONJ
can-224	42	36	liquid	liquid	ADJ
can-224	42	37	drugs	drug	NOUN
can-224	42	38	,	,	PUNCT
can-224	42	39	wrapped	wrap	VERB
can-224	42	40	by	by	ADP
can-224	42	41	polymer	polymer	NOUN
can-224	42	42	fi	fi	NOUN
can-224	42	43	lms	lm	NOUN
can-224	42	44	of	of	ADP
can-224	42	45	natural	natural	ADJ
can-224	42	46	or	or	CCONJ
can-224	42	47	synthetic	synthetic	ADJ
can-224	42	48	polymers	polymer	NOUN
can-224	42	49	.	.	PUNCT
can-224	43	1	nano	nano	NOUN
can-224	43	2	emulsion	emulsion	NOUN
can-224	43	3	is	be	AUX
can-224	43	4	also	also	ADV
can-224	43	5	known	know	VERB
can-224	43	6	as	as	ADP
can-224	43	7	micro	micro	ADJ
can-224	43	8	emulsion	emulsion	NOUN
can-224	43	9	,	,	PUNCT
can-224	43	10	particle	particle	NOUN
can-224	43	11	size	size	NOUN
can-224	43	12	10	10	NUM
can-224	43	13	-	-	SYM
can-224	43	14	100	100	NUM
can-224	43	15	nm	nm	NOUN
can-224	43	16	between	between	ADV
can-224	43	17	,	,	PUNCT
can-224	43	18	usually	usually	ADV
can-224	43	19	,	,	PUNCT
can-224	43	20	nano	nano	NOUN
can-224	43	21	-	-	PUNCT
can-224	43	22	emulsion	emulsion	NOUN
can-224	43	23	is	be	AUX
can-224	43	24	composed	compose	VERB
can-224	43	25	of	of	ADP
can-224	43	26	oil	oil	NOUN
can-224	43	27	,	,	PUNCT
can-224	43	28	water	water	NOUN
can-224	43	29	,	,	PUNCT
can-224	43	30	surfactant	surfactant	NOUN
can-224	43	31	and	and	CCONJ
can-224	43	32	surfactant	surfactant	ADJ
can-224	43	33	composition	composition	NOUN
can-224	43	34	of	of	ADP
can-224	43	35	the	the	DET
can-224	43	36	colloidal	colloidal	NOUN
can-224	43	37	dispersion	dispersion	NOUN
can-224	43	38	system	system	NOUN
can-224	43	39	,	,	PUNCT
can-224	43	40	the	the	DET
can-224	43	41	general	general	ADJ
can-224	43	42	formation	formation	NOUN
can-224	43	43	of	of	ADP
can-224	43	44	spherical	spherical	ADJ
can-224	43	45	droplets	droplet	NOUN
can-224	43	46	can	can	AUX
can-224	43	47	make	make	VERB
can-224	43	48	the	the	DET
can-224	43	49	size	size	NOUN
can-224	43	50	of	of	ADP
can-224	43	51	the	the	DET
can-224	43	52	more	more	ADV
can-224	43	53	uniform	uniform	ADJ
can-224	43	54	,	,	PUNCT
can-224	43	55	transparent	transparent	ADJ
can-224	43	56	or	or	CCONJ
can-224	43	57	translucent	translucent	ADJ
can-224	43	58	,	,	PUNCT
can-224	43	59	and	and	CCONJ
can-224	43	60	have	have	VERB
can-224	43	61	the	the	DET
can-224	43	62	thermodynamic	thermodynamic	ADJ
can-224	43	63	stability	stability	NOUN
can-224	43	64	,	,	PUNCT
can-224	43	65	mild	mild	ADJ
can-224	43	66	preparation	preparation	NOUN
can-224	43	67	conditions	condition	NOUN
can-224	43	68	make	make	VERB
can-224	43	69	nano	nano	NOUN
can-224	43	70	-	-	PUNCT
can-224	43	71	emulsion	emulsion	NOUN
can-224	43	72	physical	physical	ADJ
can-224	43	73	stability	stability	NOUN
can-224	43	74	better	well	ADV
can-224	43	75	,	,	PUNCT
can-224	43	76	can	can	AUX
can-224	43	77	enhance	enhance	VERB
can-224	43	78	the	the	DET
can-224	43	79	stability	stability	NOUN
can-224	43	80	of	of	ADP
can-224	43	81	the	the	DET
can-224	43	82	drug	drug	NOUN
can-224	43	83	;	;	PUNCT
can-224	43	84	by	by	ADP
can-224	43	85	dissolving	dissolve	VERB
can-224	43	86	the	the	DET
can-224	43	87	oil	oil	NOUN
can-224	43	88	phase	phase	NOUN
can-224	43	89	and	and	CCONJ
can-224	43	90	surfactant	surfactant	NOUN
can-224	43	91	chain	chain	NOUN
can-224	43	92	,	,	PUNCT
can-224	43	93	can	can	AUX
can-224	43	94	improve	improve	VERB
can-224	43	95	the	the	DET
can-224	43	96	drug	drug	NOUN
can-224	43	97	the	the	DET
can-224	43	98	solubility	solubility	NOUN
can-224	43	99	of	of	ADP
can-224	43	100	drugs	drug	NOUN
can-224	43	101	and	and	CCONJ
can-224	43	102	promote	promote	VERB
can-224	43	103	drug	drug	NOUN
can-224	43	104	absorption	absorption	NOUN
can-224	43	105	,	,	PUNCT
can-224	43	106	improve	improve	VERB
can-224	43	107	drug	drug	NOUN
can-224	43	108	utilization	utilization	NOUN
can-224	43	109	of	of	ADP
can-224	43	110	nano	nano	NOUN
can-224	43	111	emulsion	emulsion	NOUN
can-224	43	112	is	be	AUX
can-224	43	113	a	a	DET
can-224	43	114	new	new	ADJ
can-224	43	115	type	type	NOUN
can-224	43	116	of	of	ADP
can-224	43	117	drug	drug	NOUN
can-224	43	118	carrier	carrier	NOUN
can-224	43	119	[	[	X
can-224	43	120	5	5	NUM
can-224	43	121	]	]	PUNCT
can-224	43	122	.	.	PUNCT
can-224	44	1	nano	nano	NOUN
can-224	44	2	micelles	micelle	NOUN
can-224	44	3	can	can	AUX
can-224	44	4	be	be	AUX
can-224	44	5	prepared	prepare	VERB
can-224	44	6	by	by	ADP
can-224	44	7	block	block	NOUN
can-224	44	8	polymer	polymer	NOUN
can-224	44	9	nano	nano	NOUN
can-224	44	10	-	-	PUNCT
can-224	44	11	micelles	micelle	NOUN
can-224	44	12	as	as	ADP
can-224	44	13	a	a	DET
can-224	44	14	drug	drug	NOUN
can-224	44	15	carrier	carrier	NOUN
can-224	44	16	,	,	PUNCT
can-224	44	17	self	self	NOUN
can-224	44	18	-	-	PUNCT
can-224	44	19	assembled	assemble	VERB
can-224	44	20	structure	structure	NOUN
can-224	44	21	formed	form	VERB
can-224	44	22	in	in	ADP
can-224	44	23	water	water	NOUN
can-224	44	24	is	be	AUX
can-224	44	25	amphiphilic	amphiphilic	ADJ
can-224	44	26	block	block	NOUN
can-224	44	27	polymer	polymer	NOUN
can-224	44	28	dissolved	dissolve	VERB
can-224	44	29	synthesis	synthesis	NOUN
can-224	44	30	,	,	PUNCT
can-224	44	31	the	the	DET
can-224	44	32	particle	particle	NOUN
can-224	44	33	size	size	NOUN
can-224	44	34	is	be	AUX
can-224	44	35	generally	generally	ADV
can-224	44	36	5nm-100	5nm-100	ADJ
can-224	44	37	nm	nm	NOUN
can-224	44	38	.	.	PUNCT
can-224	45	1	its	its	PRON
can-224	45	2	advantages	advantage	NOUN
can-224	45	3	are	be	AUX
can-224	45	4	:	:	PUNCT
can-224	45	5	high	high	ADJ
can-224	45	6	drug	drug	NOUN
can-224	45	7	dose	dose	NOUN
can-224	45	8	,	,	PUNCT
can-224	45	9	wide	wide	ADJ
can-224	45	10	range	range	NOUN
can-224	45	11	,	,	PUNCT
can-224	45	12	strong	strong	ADJ
can-224	45	13	stability	stability	NOUN
can-224	45	14	,	,	PUNCT
can-224	45	15	the	the	DET
can-224	45	16	role	role	NOUN
can-224	45	17	of	of	ADP
can-224	45	18	a	a	DET
can-224	45	19	long	long	ADJ
can-224	45	20	time	time	NOUN
can-224	45	21	,	,	PUNCT
can-224	45	22	the	the	DET
can-224	45	23	unique	unique	ADJ
can-224	45	24	distribution	distribution	NOUN
can-224	45	25	,	,	PUNCT
can-224	45	26	high	high	ADJ
can-224	45	27	utilization	utilization	NOUN
can-224	45	28	,	,	PUNCT
can-224	45	29	toxicity	toxicity	NOUN
can-224	45	30	,	,	PUNCT
can-224	45	31	is	be	AUX
can-224	45	32	widely	widely	ADV
can-224	45	33	used	use	VERB
can-224	45	34	as	as	ADP
can-224	45	35	anti	anti	ADJ
can-224	45	36	-	-	ADJ
can-224	45	37	cancer	cancer	ADJ
can-224	45	38	drugs	drug	NOUN
can-224	45	39	,	,	PUNCT
can-224	45	40	antibiotics	antibiotic	NOUN
can-224	45	41	,	,	PUNCT
can-224	45	42	antihypertensive	antihypertensive	ADJ
can-224	45	43	drugs	drug	NOUN
can-224	45	44	and	and	CCONJ
can-224	45	45	genes	gene	NOUN
can-224	45	46	treatment	treatment	NOUN
can-224	45	47	of	of	ADP
can-224	45	48	drugs	drug	NOUN
can-224	45	49	and	and	CCONJ
can-224	45	50	other	other	ADJ
can-224	45	51	hydrophobic	hydrophobic	NOUN
can-224	45	52	drugs	drug	NOUN
can-224	45	53	contained	contain	VERB
can-224	45	54	[	[	X
can-224	45	55	6	6	NUM
can-224	45	56	]	]	PUNCT
can-224	45	57	.	.	PUNCT
can-224	46	1	nanoparticles	nanoparticle	NOUN
can-224	46	2	suspension	suspension	VERB
can-224	46	3	nano	nano	NOUN
can-224	46	4	-	-	PUNCT
can-224	46	5	suspensions	suspension	NOUN
can-224	46	6	under	under	ADP
can-224	46	7	certain	certain	ADJ
can-224	46	8	conditions	condition	NOUN
can-224	46	9	,	,	PUNCT
can-224	46	10	special	special	ADJ
can-224	46	11	techniques	technique	NOUN
can-224	46	12	and	and	CCONJ
can-224	46	13	equipment	equipment	NOUN
can-224	46	14	are	be	AUX
can-224	46	15	used	use	VERB
can-224	46	16	to	to	PART
can-224	46	17	pulverize	pulverize	VERB
can-224	46	18	the	the	DET
can-224	46	19	drug	drug	NOUN
can-224	46	20	to	to	PART
can-224	46	21	obtain	obtain	VERB
can-224	46	22	nano	nano	NOUN
can-224	46	23	-	-	PUNCT
can-224	46	24	suspensions	suspension	NOUN
can-224	46	25	.	.	PUNCT
can-224	47	1	in	in	ADP
can-224	47	2	addition	addition	NOUN
can-224	47	3	to	to	ADP
can-224	47	4	increasing	increase	VERB
can-224	47	5	the	the	DET
can-224	47	6	adhesion	adhesion	NOUN
can-224	47	7	and	and	CCONJ
can-224	47	8	the	the	DET
can-224	47	9	crystalline	crystalline	ADJ
can-224	47	10	structure	structure	NOUN
can-224	47	11	of	of	ADP
can-224	47	12	the	the	DET
can-224	47	13	amorphous	amorphous	ADJ
can-224	47	14	particles	particle	NOUN
can-224	47	15	compared	compare	VERB
can-224	47	16	to	to	ADP
can-224	47	17	conventional	conventional	ADJ
can-224	47	18	dosage	dosage	NOUN
can-224	47	19	forms	form	NOUN
can-224	47	20	,	,	PUNCT
can-224	47	21	it	it	PRON
can-224	47	22	also	also	ADV
can-224	47	23	increases	increase	VERB
can-224	47	24	the	the	DET
can-224	47	25	rate	rate	NOUN
can-224	47	26	of	of	ADP
can-224	47	27	dissolution	dissolution	NOUN
can-224	47	28	of	of	ADP
can-224	47	29	the	the	DET
can-224	47	30	poor	poor	ADJ
can-224	47	31	solubility	solubility	NOUN
can-224	47	32	of	of	ADP
can-224	47	33	the	the	DET
can-224	47	34	poorly	poorly	ADV
can-224	47	35	soluble	soluble	ADJ
can-224	47	36	drug	drug	NOUN
can-224	47	37	,	,	PUNCT
can-224	47	38	especially	especially	ADV
can-224	47	39	for	for	ADP
can-224	47	40	large	large	ADJ
can-224	47	41	doses	dose	NOUN
can-224	47	42	of	of	ADP
can-224	47	43	soluble	soluble	ADJ
can-224	47	44	or	or	CCONJ
can-224	47	45	injectable	injectable	ADJ
can-224	47	46	poor	poor	ADJ
can-224	47	47	absorption	absorption	NOUN
can-224	47	48	of	of	ADP
can-224	47	49	oral	oral	ADJ
can-224	47	50	medications	medication	NOUN
can-224	47	51	.	.	PUNCT
can-224	48	1	such	such	ADJ
can-224	48	2	as	as	SCONJ
can-224	48	3	the	the	DET
can-224	48	4	anti	anti	ADJ
can-224	48	5	-	-	ADJ
can-224	48	6	aids	aids	ADJ
can-224	48	7	drug	drug	NOUN
can-224	48	8	bupravaquone	bupravaquone	NOUN
can-224	48	9	in	in	ADP
can-224	48	10	the	the	DET
can-224	48	11	mucosal	mucosal	NOUN
can-224	48	12	adhesion	adhesion	NOUN
can-224	48	13	of	of	ADP
can-224	48	14	nano	nano	NOUN
can-224	48	15	-	-	PUNCT
can-224	48	16	suspension	suspension	NOUN
can-224	48	17	preparation	preparation	NOUN
can-224	48	18	,	,	PUNCT
can-224	48	19	bioavailability	bioavailability	NOUN
can-224	48	20	of	of	ADP
can-224	48	21	up	up	ADP
can-224	48	22	to	to	PART
can-224	48	23	40	40	NUM
can-224	48	24	%	%	NOUN
can-224	48	25	,	,	PUNCT
can-224	48	26	and	and	CCONJ
can-224	48	27	the	the	DET
can-224	48	28	eff	eff	PROPN
can-224	48	29	ect	ect	X
can-224	48	30	is	be	AUX
can-224	48	31	improved	improve	VERB
can-224	48	32	,	,	PUNCT
can-224	48	33	and	and	CCONJ
can-224	48	34	the	the	DET
can-224	48	35	dose	dose	NOUN
can-224	48	36	is	be	AUX
can-224	48	37	greatly	greatly	ADV
can-224	48	38	reduced	reduce	VERB
can-224	48	39	[	[	X
can-224	48	40	7	7	NUM
can-224	48	41	]	]	PUNCT
can-224	48	42	.	.	PUNCT
can-224	49	1	drugs	drug	NOUN
can-224	49	2	are	be	AUX
can-224	49	3	formed	form	VERB
can-224	49	4	by	by	ADP
can-224	49	5	covalent	covalent	ADJ
can-224	49	6	bonds	bond	NOUN
can-224	49	7	with	with	ADP
can-224	49	8	lipids	lipid	NOUN
can-224	49	9	to	to	PART
can-224	49	10	form	form	VERB
can-224	49	11	drug	drug	NOUN
can-224	49	12	bodies	body	NOUN
can-224	49	13	,	,	PUNCT
can-224	49	14	which	which	PRON
can-224	49	15	are	be	AUX
can-224	49	16	automatically	automatically	ADV
can-224	49	17	formed	form	VERB
can-224	49	18	due	due	ADP
can-224	49	19	to	to	ADP
can-224	49	20	changes	change	NOUN
can-224	49	21	in	in	ADP
can-224	49	22	the	the	DET
can-224	49	23	solubility	solubility	NOUN
can-224	49	24	characteristics	characteristic	NOUN
can-224	49	25	in	in	ADP
can-224	49	26	the	the	DET
can-224	49	27	medium	medium	NOUN
can-224	49	28	.	.	PUNCT
can-224	50	1	drug	drug	NOUN
can-224	50	2	quality	quality	NOUN
can-224	50	3	is	be	AUX
can-224	50	4	a	a	DET
can-224	50	5	new	new	ADJ
can-224	50	6	type	type	NOUN
can-224	50	7	of	of	ADP
can-224	50	8	drug	drug	NOUN
can-224	50	9	delivery	delivery	NOUN
can-224	50	10	system	system	NOUN
can-224	50	11	;	;	PUNCT
can-224	50	12	particle	particle	NOUN
can-224	50	13	size	size	NOUN
can-224	50	14	range	range	NOUN
can-224	50	15	is	be	AUX
can-224	50	16	generally	generally	ADV
can-224	50	17	10	10	NUM
can-224	50	18	-	-	SYM
can-224	50	19	200	200	NUM
can-224	50	20	nm	nm	NOUN
can-224	50	21	.	.	PUNCT
can-224	51	1	drugs	drug	NOUN
can-224	51	2	are	be	AUX
can-224	51	3	nanoparticles	nanoparticle	NOUN
can-224	51	4	,	,	PUNCT
can-224	51	5	and	and	CCONJ
can-224	51	6	they	they	PRON
can-224	51	7	also	also	ADV
can-224	51	8	overcome	overcome	VERB
can-224	51	9	the	the	DET
can-224	51	10	shortcomings	shortcoming	NOUN
can-224	51	11	of	of	ADP
can-224	51	12	drug	drug	NOUN
can-224	51	13	leakage	leakage	NOUN
can-224	51	14	and	and	CCONJ
can-224	51	15	skeleton	skeleton	NOUN
can-224	51	16	instability	instability	NOUN
can-224	51	17	,	,	PUNCT
can-224	51	18	improve	improve	VERB
can-224	51	19	drug	drug	NOUN
can-224	51	20	targeting	targeting	NOUN
can-224	51	21	and	and	CCONJ
can-224	51	22	biocompatibility	biocompatibility	NOUN
can-224	51	23	,	,	PUNCT
can-224	51	24	and	and	CCONJ
can-224	51	25	increase	increase	VERB
can-224	51	26	stability	stability	NOUN
can-224	51	27	[	[	X
can-224	51	28	8	8	NUM
can-224	51	29	]	]	PUNCT
can-224	51	30	.	.	PUNCT
can-224	52	1	advances	advance	NOUN
can-224	52	2	in	in	ADP
can-224	52	3	synthesis	synthesis	NOUN
can-224	52	4	and	and	CCONJ
can-224	52	5	application	application	NOUN
can-224	52	6	of	of	ADP
can-224	52	7	nanometer	nanometer	NOUN
can-224	52	8	drug	drug	NOUN
can-224	52	9	carriers	carrier	NOUN
can-224	52	10	14	14	NUM
can-224	52	11	nano	nano	NOUN
can-224	52	12	-	-	PUNCT
can-224	52	13	drug	drug	NOUN
can-224	52	14	carrier	carrier	NOUN
can-224	52	15	types	type	NOUN
can-224	52	16	are	be	AUX
can-224	52	17	rich	rich	ADJ
can-224	52	18	and	and	CCONJ
can-224	52	19	varied	varied	ADJ
can-224	52	20	,	,	PUNCT
can-224	52	21	more	more	ADV
can-224	52	22	common	common	ADJ
can-224	52	23	with	with	ADP
can-224	52	24	polymer	polymer	NOUN
can-224	52	25	micelles	micelle	NOUN
can-224	52	26	,	,	PUNCT
can-224	52	27	liposomes	liposome	NOUN
can-224	52	28	nanoparticles	nanoparticle	NOUN
can-224	52	29	,	,	PUNCT
can-224	52	30	polymer	polymer	NOUN
can-224	52	31	-	-	PUNCT
can-224	52	32	drug	drug	NOUN
can-224	52	33	copolymers	copolymer	NOUN
can-224	52	34	,	,	PUNCT
can-224	52	35	ceramic	ceramic	ADJ
can-224	52	36	nanoparticles	nanoparticle	NOUN
can-224	52	37	,	,	PUNCT
can-224	52	38	carbon	carbon	NOUN
can-224	52	39	nanotubes	nanotube	NOUN
can-224	52	40	,	,	PUNCT
can-224	52	41	etc	etc	X
can-224	52	42	.	.	X
can-224	52	43	,	,	PUNCT
can-224	52	44	according	accord	VERB
can-224	52	45	to	to	ADP
can-224	52	46	its	its	PRON
can-224	52	47	characteristics	characteristic	NOUN
can-224	52	48	are	be	AUX
can-224	52	49	applied	apply	VERB
can-224	52	50	to	to	ADP
can-224	52	51	diff	diff	NOUN
can-224	52	52	erent	erent	NOUN
can-224	52	53	drug	drug	NOUN
can-224	52	54	delivery	delivery	NOUN
can-224	52	55	system	system	NOUN
can-224	52	56	the	the	DET
can-224	52	57	nano	nano	NOUN
can-224	52	58	-	-	PUNCT
can-224	52	59	drug	drug	NOUN
can-224	52	60	carrier	carrier	NOUN
can-224	52	61	structure	structure	NOUN
can-224	52	62	.	.	PUNCT
can-224	53	1	2.3	2.3	NUM
can-224	53	2	.	.	PUNCT
can-224	54	1	transport	transport	NOUN
can-224	54	2	of	of	ADP
can-224	54	3	nano	nano	NOUN
can-224	54	4	-	-	PUNCT
can-224	54	5	drug	drug	NOUN
can-224	54	6	carriers	carrier	NOUN
can-224	54	7	in	in	ADP
can-224	54	8	general	general	ADJ
can-224	54	9	,	,	PUNCT
can-224	54	10	nanoparticles	nanoparticle	NOUN
can-224	54	11	are	be	AUX
can-224	54	12	engulfed	engulf	VERB
can-224	54	13	by	by	ADP
can-224	54	14	the	the	DET
can-224	54	15	reticular	reticular	ADJ
can-224	54	16	endothelial	endothelial	ADJ
can-224	54	17	system	system	NOUN
can-224	54	18	during	during	ADP
can-224	54	19	circulation	circulation	NOUN
can-224	54	20	,	,	PUNCT
can-224	54	21	and	and	CCONJ
can-224	54	22	the	the	DET
can-224	54	23	flow	flow	NOUN
can-224	54	24	of	of	ADP
can-224	54	25	nanoparticles	nanoparticle	NOUN
can-224	54	26	is	be	AUX
can-224	54	27	aff	aff	AUX
can-224	54	28	ected	ecte	VERB
can-224	54	29	by	by	ADP
can-224	54	30	their	their	PRON
can-224	54	31	size	size	NOUN
can-224	54	32	and	and	CCONJ
can-224	54	33	surface	surface	NOUN
can-224	54	34	characteristics	characteristic	NOUN
can-224	54	35	[	[	X
can-224	54	36	9	9	NUM
can-224	54	37	]	]	PUNCT
can-224	54	38	.	.	PUNCT
can-224	55	1	diameter	diameter	NOUN
can-224	55	2	size	size	NOUN
can-224	55	3	can	can	AUX
can-224	55	4	be	be	AUX
can-224	55	5	adjusted	adjust	VERB
can-224	55	6	to	to	PART
can-224	55	7	be	be	AUX
can-224	55	8	one	one	NUM
can-224	55	9	of	of	ADP
can-224	55	10	the	the	DET
can-224	55	11	advantages	advantage	NOUN
can-224	55	12	of	of	ADP
can-224	55	13	nanoparticles	nanoparticle	NOUN
can-224	55	14	.	.	PUNCT
can-224	56	1	but	but	CCONJ
can-224	56	2	the	the	DET
can-224	56	3	particles	particle	NOUN
can-224	56	4	can	can	AUX
can-224	56	5	not	not	PART
can-224	56	6	be	be	AUX
can-224	56	7	too	too	ADV
can-224	56	8	large	large	ADJ
can-224	56	9	,	,	PUNCT
can-224	56	10	otherwise	otherwise	ADV
can-224	56	11	it	it	PRON
can-224	56	12	is	be	AUX
can-224	56	13	engulfed	engulf	VERB
can-224	56	14	by	by	ADP
can-224	56	15	the	the	DET
can-224	56	16	macrophages	macrophage	NOUN
can-224	56	17	of	of	ADP
can-224	56	18	the	the	DET
can-224	56	19	reticuloendothelial	reticuloendothelial	ADJ
can-224	56	20	system	system	NOUN
can-224	56	21	.	.	PUNCT
can-224	57	1	particle	particle	NOUN
can-224	57	2	size	size	NOUN
can-224	57	3	of	of	ADP
can-224	57	4	100	100	NUM
can-224	57	5	-	-	SYM
can-224	57	6	150	150	NUM
can-224	57	7	nm	nm	ADJ
can-224	57	8	nanoparticles	nanoparticle	NOUN
can-224	57	9	for	for	ADP
can-224	57	10	the	the	DET
can-224	57	11	most	most	ADJ
can-224	57	12	eff	eff	PROPN
can-224	57	13	ective	ective	NOUN
can-224	57	14	.	.	PUNCT
can-224	58	1	in	in	ADP
can-224	58	2	addition	addition	NOUN
can-224	58	3	to	to	ADP
can-224	58	4	particle	particle	NOUN
can-224	58	5	size	size	NOUN
can-224	58	6	,	,	PUNCT
can-224	58	7	in	in	ADP
can-224	58	8	the	the	DET
can-224	58	9	vascular	vascular	ADJ
can-224	58	10	circulation	circulation	NOUN
can-224	58	11	is	be	AUX
can-224	58	12	also	also	ADV
can-224	58	13	affected	affect	VERB
can-224	58	14	by	by	ADP
can-224	58	15	the	the	DET
can-224	58	16	surface	surface	NOUN
can-224	58	17	characteristics	characteristic	NOUN
can-224	58	18	.	.	PUNCT
can-224	59	1	ideally	ideally	ADV
can-224	59	2	,	,	PUNCT
can-224	59	3	the	the	DET
can-224	59	4	nanoparticles	nanoparticle	NOUN
can-224	59	5	will	will	AUX
can-224	59	6	have	have	VERB
can-224	59	7	a	a	DET
can-224	59	8	longer	long	ADJ
can-224	59	9	cycle	cycle	NOUN
can-224	59	10	time	time	NOUN
can-224	59	11	on	on	ADP
can-224	59	12	the	the	DET
can-224	59	13	hydrophilic	hydrophilic	ADJ
can-224	59	14	surface	surface	NOUN
can-224	59	15	of	of	ADP
can-224	59	16	the	the	DET
can-224	59	17	blood	blood	NOUN
can-224	59	18	vessel	vessel	NOUN
can-224	59	19	.	.	PUNCT
can-224	60	1	can	can	AUX
can-224	60	2	be	be	AUX
can-224	60	3	obtained	obtain	VERB
can-224	60	4	by	by	ADP
can-224	60	5	two	two	NUM
can-224	60	6	methods	method	NOUN
can-224	60	7	,	,	PUNCT
can-224	60	8	namely	namely	ADV
can-224	60	9	,	,	PUNCT
can-224	60	10	nanoparticles	nanoparticle	NOUN
can-224	60	11	modifi	modifi	PROPN
can-224	60	12	ed	ed	PROPN
can-224	60	13	by	by	ADP
can-224	60	14	hydrophilic	hydrophilic	ADJ
can-224	60	15	polymers	polymer	NOUN
can-224	60	16	,	,	PUNCT
can-224	60	17	or	or	CCONJ
can-224	60	18	hydrophobic	hydrophobic	NOUN
can-224	60	19	and	and	CCONJ
can-224	60	20	hydrophobic	hydrophobic	NOUN
can-224	60	21	copolymerization	copolymerization	NOUN
can-224	60	22	to	to	PART
can-224	60	23	form	form	VERB
can-224	60	24	hydrophobic	hydrophobic	NOUN
can-224	60	25	core	core	NOUN
can-224	60	26	,	,	PUNCT
can-224	60	27	hydrophilic	hydrophilic	ADJ
can-224	60	28	shell	shell	NOUN
can-224	60	29	of	of	ADP
can-224	60	30	nanoparticles	nanoparticle	NOUN
can-224	60	31	.	.	PUNCT
can-224	61	1	however	however	ADV
can-224	61	2	,	,	PUNCT
can-224	61	3	changing	change	VERB
can-224	61	4	the	the	DET
can-224	61	5	surface	surface	NOUN
can-224	61	6	charge	charge	NOUN
can-224	61	7	of	of	ADP
can-224	61	8	nanoparticles	nanoparticle	NOUN
can-224	61	9	can	can	AUX
can-224	61	10	aff	aff	AUX
can-224	61	11	ect	ect	VERB
can-224	61	12	their	their	PRON
can-224	61	13	fate	fate	NOUN
can-224	61	14	,	,	PUNCT
can-224	61	15	for	for	ADP
can-224	61	16	example	example	NOUN
can-224	61	17	,	,	PUNCT
can-224	61	18	neutral	neutral	ADJ
can-224	61	19	nanoparticles	nanoparticle	NOUN
can-224	61	20	are	be	AUX
can-224	61	21	negligible	negligible	ADJ
can-224	61	22	compared	compare	VERB
can-224	61	23	to	to	ADP
can-224	61	24	negative	negative	ADJ
can-224	61	25	and	and	CCONJ
can-224	61	26	positive	positive	ADJ
can-224	61	27	nanoparticles	nanoparticle	NOUN
can-224	61	28	when	when	SCONJ
can-224	61	29	ingested	ingested	ADJ
can-224	61	30	cells	cell	NOUN
can-224	61	31	are	be	AUX
can-224	61	32	ingested	ingest	VERB
can-224	61	33	.	.	PUNCT
can-224	62	1	meet	meet	VERB
can-224	62	2	the	the	DET
can-224	62	3	above	above	ADJ
can-224	62	4	conditions	condition	NOUN
can-224	62	5	,	,	PUNCT
can-224	62	6	can	can	AUX
can-224	62	7	better	well	ADV
can-224	62	8	reach	reach	VERB
can-224	62	9	the	the	DET
can-224	62	10	recipient	recipient	NOUN
can-224	62	11	tissue	tissue	NOUN
can-224	62	12	.	.	PUNCT
can-224	63	1	binary	binary	ADJ
can-224	63	2	complex	complex	NOUN
can-224	63	3	in	in	ADP
can-224	63	4	the	the	DET
can-224	63	5	drug	drug	NOUN
can-224	63	6	transport	transport	NOUN
can-224	63	7	target	target	NOUN
can-224	63	8	eff	eff	PROPN
can-224	63	9	ect	ect	VERB
can-224	63	10	is	be	AUX
can-224	63	11	not	not	PART
can-224	63	12	satisfactory	satisfactory	ADJ
can-224	63	13	,	,	PUNCT
can-224	63	14	only	only	ADV
can-224	63	15	on	on	ADP
can-224	63	16	the	the	DET
can-224	63	17	macrophages	macrophage	NOUN
can-224	63	18	are	be	AUX
can-224	63	19	more	more	ADV
can-224	63	20	concentrated	concentrated	ADJ
can-224	63	21	organs	organ	NOUN
can-224	63	22	have	have	VERB
can-224	63	23	a	a	DET
can-224	63	24	certain	certain	ADJ
can-224	63	25	eff	eff	PROPN
can-224	63	26	ect	ect	X
can-224	63	27	[	[	X
can-224	63	28	10	10	NUM
can-224	63	29	]	]	PUNCT
can-224	63	30	.	.	PUNCT
can-224	64	1	but	but	CCONJ
can-224	64	2	can	can	AUX
can-224	64	3	be	be	AUX
can-224	64	4	selected	select	VERB
can-224	64	5	specifi	specifi	PROPN
can-224	64	6	c	c	PROPN
can-224	64	7	ligand	ligand	PROPN
can-224	64	8	or	or	CCONJ
can-224	64	9	antibody	antibody	NOUN
can-224	64	10	linked	link	VERB
can-224	64	11	to	to	ADP
can-224	64	12	the	the	DET
can-224	64	13	binary	binary	PROPN
can-224	64	14	match	match	NOUN
can-224	64	15	to	to	PART
can-224	64	16	overcome	overcome	VERB
can-224	64	17	the	the	DET
can-224	64	18	above	above	ADJ
can-224	64	19	problems	problem	NOUN
can-224	64	20	.	.	PUNCT
can-224	65	1	active	active	ADJ
can-224	65	2	targeting	targeting	NOUN
can-224	65	3	refers	refer	VERB
can-224	65	4	to	to	ADP
can-224	65	5	a	a	DET
can-224	65	6	drug	drug	NOUN
can-224	65	7	delivery	delivery	NOUN
can-224	65	8	system	system	NOUN
can-224	65	9	constructed	construct	VERB
can-224	65	10	by	by	ADP
can-224	65	11	specifi	specifi	PROPN
can-224	65	12	cally	cally	ADV
can-224	65	13	interacting	interact	VERB
can-224	65	14	and	and	CCONJ
can-224	65	15	enriching	enrich	VERB
can-224	65	16	specifi	specifi	PROPN
can-224	65	17	c	c	NOUN
can-224	65	18	organs	organ	NOUN
can-224	65	19	,	,	PUNCT
can-224	65	20	tissues	tissue	NOUN
can-224	65	21	,	,	PUNCT
can-224	65	22	or	or	CCONJ
can-224	65	23	cells	cell	NOUN
can-224	65	24	by	by	ADP
can-224	65	25	means	mean	NOUN
can-224	65	26	of	of	ADP
can-224	65	27	certain	certain	ADJ
can-224	65	28	specifi	specifi	PROPN
can-224	65	29	c	c	PROPN
can-224	65	30	biochemical	biochemical	ADJ
can-224	65	31	environments	environment	NOUN
can-224	65	32	in	in	ADP
can-224	65	33	the	the	DET
can-224	65	34	organism	organism	NOUN
can-224	65	35	,	,	PUNCT
can-224	65	36	or	or	CCONJ
can-224	65	37	by	by	ADP
can-224	65	38	the	the	DET
can-224	65	39	antigen	antigen	NOUN
can-224	65	40	-	-	PUNCT
can-224	65	41	antibody	antibody	NOUN
can-224	65	42	response	response	NOUN
can-224	65	43	mechanism	mechanism	NOUN
can-224	65	44	of	of	ADP
can-224	65	45	the	the	DET
can-224	65	46	organism	organism	NOUN
can-224	65	47	.	.	PUNCT
can-224	66	1	according	accord	VERB
can-224	66	2	to	to	ADP
can-224	66	3	diff	diff	NOUN
can-224	66	4	erent	erent	NOUN
can-224	66	5	mechanisms	mechanism	NOUN
can-224	66	6	of	of	ADP
can-224	66	7	action	action	NOUN
can-224	66	8	,	,	PUNCT
can-224	66	9	active	active	ADJ
can-224	66	10	targeting	targeting	NOUN
can-224	66	11	is	be	AUX
can-224	66	12	divided	divide	VERB
can-224	66	13	into	into	ADP
can-224	66	14	antigen	antigen	NOUN
can-224	66	15	-	-	PUNCT
can-224	66	16	antibody	antibody	NOUN
can-224	66	17	binding	bind	VERB
can-224	66	18	targeting	target	VERB
can-224	66	19	and	and	CCONJ
can-224	66	20	ligand	ligand	NOUN
can-224	66	21	-	-	PUNCT
can-224	66	22	receptor	receptor	NOUN
can-224	66	23	binding	bind	VERB
can-224	66	24	targeting	targeting	NOUN
can-224	66	25	.	.	PUNCT
can-224	67	1	3	3	X
can-224	67	2	.	.	PUNCT
can-224	67	3	preparation	preparation	NOUN
can-224	67	4	methods	method	NOUN
can-224	67	5	of	of	ADP
can-224	67	6	nanometer	nanometer	NOUN
can-224	67	7	drug	drug	NOUN
can-224	67	8	carriers	carrier	NOUN
can-224	67	9	3.1	3.1	NUM
can-224	67	10	.	.	PUNCT
can-224	67	11	liposomes	liposome	VERB
can-224	67	12	the	the	DET
can-224	67	13	overall	overall	ADJ
can-224	67	14	structure	structure	NOUN
can-224	67	15	of	of	ADP
can-224	67	16	the	the	DET
can-224	67	17	nano	nano	NOUN
can-224	67	18	-	-	PUNCT
can-224	67	19	drug	drug	NOUN
can-224	67	20	carrier	carrier	NOUN
can-224	67	21	is	be	AUX
can-224	67	22	liposomes	liposome	NOUN
can-224	67	23	,	,	PUNCT
can-224	67	24	which	which	PRON
can-224	67	25	are	be	AUX
can-224	67	26	the	the	DET
can-224	67	27	earliest	early	ADJ
can-224	67	28	developed	develop	VERB
can-224	67	29	nano	nano	NOUN
can-224	67	30	-	-	PUNCT
can-224	67	31	drug	drug	NOUN
can-224	67	32	carriers	carrier	NOUN
can-224	67	33	before	before	ADV
can-224	67	34	,	,	PUNCT
can-224	67	35	until	until	ADP
can-224	67	36	now	now	ADV
can-224	67	37	,	,	PUNCT
can-224	67	38	liposomes	liposome	NOUN
can-224	67	39	have	have	AUX
can-224	67	40	also	also	ADV
can-224	67	41	improved	improve	VERB
can-224	67	42	and	and	CCONJ
can-224	67	43	used	use	VERB
can-224	67	44	in	in	ADP
can-224	67	45	more	more	ADJ
can-224	67	46	disease	disease	NOUN
can-224	67	47	treatments	treatment	NOUN
can-224	67	48	.	.	PUNCT
can-224	68	1	membrane	membrane	ADJ
can-224	68	2	evaporation	evaporation	NOUN
can-224	69	1	[	[	X
can-224	69	2	11	11	NUM
can-224	69	3	]	]	PUNCT
can-224	69	4	,	,	PUNCT
can-224	69	5	jianping	jianping	NOUN
can-224	69	6	wu	wu	PROPN
can-224	69	7	,	,	PUNCT
can-224	69	8	et	et	PROPN
can-224	69	9	al	al	PROPN
can-224	69	10	15	15	NUM
can-224	69	11	reversed	reverse	VERB
can-224	69	12	-	-	PUNCT
can-224	69	13	phase	phase	NOUN
can-224	69	14	evaporation	evaporation	NOUN
can-224	69	15	[	[	X
can-224	69	16	12	12	NUM
can-224	69	17	]	]	X
can-224	69	18	,	,	PUNCT
can-224	69	19	thin	thin	ADJ
can-224	69	20	-	-	PUNCT
can-224	69	21	fi	fi	NOUN
can-224	69	22	lm	lm	INTJ
can-224	69	23	ultrasonic	ultrasonic	ADJ
can-224	69	24	dispersion	dispersion	NOUN
can-224	69	25	[	[	X
can-224	69	26	13	13	NUM
can-224	69	27	]	]	PUNCT
can-224	69	28	and	and	CCONJ
can-224	69	29	so	so	ADV
can-224	69	30	on	on	ADV
can-224	69	31	are	be	AUX
can-224	69	32	the	the	DET
can-224	69	33	main	main	ADJ
can-224	69	34	methods	method	NOUN
can-224	69	35	for	for	ADP
can-224	69	36	the	the	DET
can-224	69	37	synthesis	synthesis	NOUN
can-224	69	38	of	of	ADP
can-224	69	39	nano	nano	NOUN
can-224	69	40	-	-	PUNCT
can-224	69	41	liposomes	liposome	NOUN
can-224	69	42	.	.	PUNCT
can-224	70	1	membrane	membrane	ADJ
can-224	70	2	evaporation	evaporation	NOUN
can-224	70	3	method	method	NOUN
can-224	70	4	in	in	ADP
can-224	70	5	the	the	DET
can-224	70	6	organic	organic	ADJ
can-224	70	7	solvent	solvent	NOUN
can-224	70	8	to	to	ADP
can-224	70	9	the	the	DET
can-224	70	10	drug	drug	NOUN
can-224	70	11	and	and	CCONJ
can-224	70	12	cholesterol	cholesterol	NOUN
can-224	70	13	,	,	PUNCT
can-224	70	14	phospholipid	phospholipid	NOUN
can-224	70	15	compatibility	compatibility	NOUN
can-224	71	1	,	,	PUNCT
can-224	71	2	the	the	DET
can-224	71	3	liposomal	liposomal	ADJ
can-224	71	4	suspension	suspension	NOUN
can-224	71	5	is	be	AUX
can-224	71	6	the	the	DET
can-224	71	7	evaporation	evaporation	NOUN
can-224	71	8	of	of	ADP
can-224	71	9	the	the	DET
can-224	71	10	solvent	solvent	NOUN
can-224	71	11	so	so	SCONJ
can-224	71	12	that	that	SCONJ
can-224	71	13	drugs	drug	NOUN
can-224	71	14	and	and	CCONJ
can-224	71	15	phospholipids	phospholipid	NOUN
can-224	71	16	and	and	CCONJ
can-224	71	17	other	other	ADJ
can-224	71	18	fi	fi	NOUN
can-224	71	19	lm	lm	ADV
can-224	71	20	-	-	PUNCT
can-224	71	21	forming	form	VERB
can-224	71	22	materials	material	NOUN
can-224	71	23	to	to	PART
can-224	71	24	form	form	VERB
can-224	71	25	a	a	DET
can-224	71	26	symmetrical	symmetrical	ADJ
can-224	71	27	lipid	lipid	NOUN
can-224	71	28	fi	fi	NOUN
can-224	71	29	lm	lm	INTJ
can-224	71	30	in	in	ADP
can-224	71	31	the	the	DET
can-224	71	32	fl	fl	NOUN
can-224	71	33	ask	ask	VERB
can-224	71	34	wall	wall	NOUN
can-224	71	35	and	and	CCONJ
can-224	71	36	added	add	VERB
can-224	71	37	to	to	ADP
can-224	71	38	the	the	DET
can-224	71	39	wash	wash	NOUN
can-224	71	40	fi	fi	NOUN
can-224	71	41	lm	lm	INTJ
can-224	71	42	rinse	rinse	NOUN
can-224	71	43	obtain	obtain	VERB
can-224	71	44	.	.	PUNCT
can-224	72	1	lvwen	lvwen	PROPN
can-224	72	2	li	li	PROPN
can-224	72	3	et	et	PROPN
can-224	72	4	al	al	PROPN
can-224	72	5	.	.	PROPN
can-224	72	6	synthesized	synthesize	VERB
can-224	72	7	50	50	NUM
can-224	72	8	nm	nm	NOUN
can-224	72	9	liposomes	liposome	NOUN
can-224	72	10	by	by	ADP
can-224	72	11	combining	combine	VERB
can-224	72	12	thin	thin	ADJ
can-224	72	13	fi	fi	NOUN
can-224	72	14	lm	lm	ADP
can-224	72	15	evaporation	evaporation	NOUN
can-224	72	16	and	and	CCONJ
can-224	72	17	freeze	freeze	NOUN
can-224	72	18	-	-	PUNCT
can-224	72	19	drying	dry	VERB
can-224	72	20	with	with	ADP
can-224	72	21	187.5	187.5	NUM
can-224	72	22	mg	mg	NOUN
can-224	72	23	of	of	ADP
can-224	72	24	phospholipid	phospholipid	NOUN
can-224	72	25	,	,	PUNCT
can-224	72	26	cholesterol	cholesterol	NOUN
can-224	72	27	,	,	PUNCT
can-224	72	28	93.8	93.8	NUM
can-224	72	29	mg	mg	NOUN
can-224	72	30	and	and	CCONJ
can-224	72	31	37.5	37.5	NUM
can-224	72	32	mg	mg	NOUN
can-224	72	33	lamp	lamp	NOUN
can-224	72	34	and	and	CCONJ
can-224	72	35	30	30	NUM
can-224	72	36	ml	ml	NOUN
can-224	72	37	of	of	ADP
can-224	72	38	dichloromethane	dichloromethane	NOUN
can-224	72	39	as	as	ADP
can-224	72	40	the	the	DET
can-224	72	41	main	main	ADJ
can-224	72	42	raw	raw	ADJ
can-224	72	43	material	material	NOUN
can-224	72	44	.	.	PUNCT
can-224	73	1	the	the	DET
can-224	73	2	aqueous	aqueous	ADJ
can-224	73	3	solution	solution	NOUN
can-224	73	4	of	of	ADP
can-224	73	5	the	the	DET
can-224	73	6	drug	drug	NOUN
can-224	73	7	is	be	AUX
can-224	73	8	added	add	VERB
can-224	73	9	to	to	ADP
can-224	73	10	the	the	DET
can-224	73	11	mixed	mixed	ADJ
can-224	73	12	solution	solution	NOUN
can-224	73	13	of	of	ADP
can-224	73	14	lecithin	lecithin	NOUN
can-224	73	15	,	,	PUNCT
can-224	73	16	cholesterol	cholesterol	NOUN
can-224	73	17	and	and	CCONJ
can-224	73	18	organic	organic	ADJ
can-224	73	19	solvent	solvent	NOUN
can-224	73	20	to	to	PART
can-224	73	21	form	form	VERB
can-224	73	22	a	a	DET
can-224	73	23	relatively	relatively	ADV
can-224	73	24	stable	stable	ADJ
can-224	73	25	cde	cde	NOUN
can-224	73	26	type	type	NOUN
can-224	73	27	emulsion	emulsion	NOUN
can-224	73	28	.	.	PUNCT
can-224	74	1	the	the	DET
can-224	74	2	organic	organic	ADJ
can-224	74	3	solvent	solvent	NOUN
can-224	74	4	is	be	AUX
can-224	74	5	removed	remove	VERB
can-224	74	6	and	and	CCONJ
can-224	74	7	the	the	DET
can-224	74	8	phosphate	phosphate	PROPN
can-224	74	9	buff	buff	PROPN
can-224	74	10	er	er	INTJ
can-224	74	11	is	be	AUX
can-224	74	12	added	add	VERB
can-224	74	13	to	to	AUX
can-224	74	14	hydrate	hydrate	VERB
can-224	74	15	and	and	CCONJ
can-224	74	16	continue	continue	VERB
can-224	74	17	to	to	PART
can-224	74	18	short	short	ADJ
can-224	74	19	-	-	PUNCT
can-224	74	20	term	term	NOUN
can-224	74	21	evaporate	evaporate	NOUN
can-224	74	22	at	at	ADP
can-224	74	23	low	low	ADJ
can-224	74	24	milky	milky	ADJ
can-224	74	25	yellow	yellow	ADJ
can-224	74	26	liposomal	liposomal	ADJ
can-224	74	27	suspension	suspension	NOUN
can-224	74	28	.	.	PUNCT
can-224	75	1	l.	l.	PROPN
can-224	75	2	liu	liu	PROPN
can-224	75	3	and	and	CCONJ
can-224	75	4	other	other	ADJ
can-224	75	5	use	use	NOUN
can-224	75	6	of	of	ADP
can-224	75	7	reverse	reverse	ADJ
can-224	75	8	phase	phase	NOUN
can-224	75	9	evaporation	evaporation	NOUN
can-224	75	10	with	with	ADP
can-224	75	11	lecithin	lecithin	NOUN
can-224	75	12	,	,	PUNCT
can-224	75	13	cholesterol	cholesterol	NOUN
can-224	75	14	,	,	PUNCT
can-224	75	15	streamside	streamside	ADV
can-224	75	16	made	make	VERB
can-224	75	17	of	of	ADP
can-224	75	18	particle	particle	NOUN
can-224	75	19	size	size	NOUN
can-224	75	20	of	of	ADP
can-224	75	21	562	562	NUM
can-224	75	22	nm	nm	ADJ
can-224	75	23	coverage	coverage	NOUN
can-224	75	24	of	of	ADP
can-224	75	25	55	55	NUM
can-224	75	26	%	%	NOUN
can-224	75	27	to	to	PART
can-224	75	28	65	65	NUM
can-224	75	29	%	%	NOUN
can-224	75	30	of	of	ADP
can-224	75	31	the	the	DET
can-224	75	32	cationic	cationic	ADJ
can-224	75	33	liposomes	liposome	NOUN
can-224	75	34	.	.	PUNCT
can-224	76	1	thin	thin	ADJ
can-224	76	2	film	film	NOUN
can-224	76	3	ultrasonic	ultrasonic	ADJ
can-224	76	4	dispersion	dispersion	NOUN
can-224	76	5	method	method	VERB
can-224	76	6	first	first	ADJ
can-224	76	7	synthesis	synthesis	NOUN
can-224	76	8	of	of	ADP
can-224	76	9	phospholipid	phospholipid	NOUN
can-224	76	10	bilayer	bilayer	NOUN
can-224	76	11	,	,	PUNCT
can-224	76	12	by	by	ADP
can-224	76	13	ultrasonic	ultrasonic	ADJ
can-224	76	14	hydration	hydration	NOUN
can-224	76	15	dispersed	disperse	VERB
can-224	76	16	liposomes	liposome	NOUN
can-224	76	17	.	.	PUNCT
can-224	77	1	y.	y.	PROPN
can-224	77	2	gu	gu	PROPN
can-224	77	3	,	,	PUNCT
can-224	77	4	y.	y.	PROPN
can-224	77	5	shi	shi	PROPN
can-224	77	6	,	,	PUNCT
can-224	77	7	who	who	PRON
can-224	77	8	used	use	VERB
can-224	77	9	emodin	emodin	PROPN
can-224	77	10	,	,	PUNCT
can-224	77	11	cholesterol	cholesterol	NOUN
can-224	77	12	,	,	PUNCT
can-224	77	13	phospholipids	phospholipid	NOUN
can-224	77	14	,	,	PUNCT
can-224	77	15	chloroform	chloroform	NOUN
can-224	77	16	prepared	prepare	VERB
can-224	77	17	a	a	DET
can-224	77	18	particle	particle	NOUN
can-224	77	19	size	size	NOUN
can-224	77	20	of	of	ADP
can-224	77	21	about	about	ADV
can-224	77	22	25	25	NUM
can-224	77	23	nm	nm	ADJ
can-224	77	24	liposomes	liposome	NOUN
can-224	77	25	.	.	PUNCT
can-224	78	1	3.2	3.2	NUM
can-224	78	2	.	.	PUNCT
can-224	78	3	emulsion	emulsion	NOUN
can-224	78	4	method	method	NOUN
can-224	78	5	nano	nano	NOUN
can-224	78	6	-	-	PUNCT
can-224	78	7	drug	drug	NOUN
can-224	78	8	in	in	ADP
can-224	78	9	the	the	DET
can-224	78	10	emulsion	emulsion	NOUN
can-224	78	11	synthesis	synthesis	NOUN
can-224	78	12	method	method	NOUN
can-224	78	13	known	know	VERB
can-224	78	14	as	as	ADP
can-224	78	15	the	the	DET
can-224	78	16	emulsion	emulsion	NOUN
can-224	78	17	method	method	NOUN
can-224	78	18	.	.	PUNCT
can-224	79	1	the	the	DET
can-224	79	2	small	small	ADJ
can-224	79	3	particles	particle	NOUN
can-224	79	4	are	be	AUX
can-224	79	5	obtained	obtain	VERB
can-224	79	6	by	by	ADP
can-224	79	7	nucleating	nucleate	VERB
can-224	79	8	the	the	DET
can-224	79	9	small	small	ADJ
can-224	79	10	droplets	droplet	NOUN
can-224	79	11	formed	form	VERB
can-224	79	12	by	by	ADP
can-224	79	13	the	the	DET
can-224	79	14	action	action	NOUN
can-224	79	15	of	of	ADP
can-224	79	16	the	the	DET
can-224	79	17	surfactant	surfactant	ADJ
can-224	79	18	dispersion	dispersion	NOUN
can-224	79	19	and	and	CCONJ
can-224	79	20	the	the	DET
can-224	79	21	external	external	ADJ
can-224	79	22	force	force	NOUN
can-224	79	23	.	.	PUNCT
can-224	80	1	but	but	CCONJ
can-224	80	2	also	also	ADV
can-224	80	3	by	by	ADP
can-224	80	4	nature	nature	NOUN
can-224	80	5	in	in	ADP
can-224	80	6	the	the	DET
can-224	80	7	emulsion	emulsion	NOUN
can-224	80	8	polymerization	polymerization	NOUN
can-224	80	9	self	self	NOUN
can-224	80	10	-	-	PUNCT
can-224	80	11	assembled	assemble	VERB
can-224	80	12	nuclei	nucleus	NOUN
can-224	80	13	.	.	PUNCT
can-224	81	1	the	the	DET
can-224	81	2	main	main	ADJ
can-224	81	3	methods	method	NOUN
can-224	81	4	:	:	PUNCT
can-224	81	5	emulsion	emulsion	NOUN
can-224	81	6	polymerization	polymerization	NOUN
can-224	81	7	,	,	PUNCT
can-224	81	8	emulsion	emulsion	NOUN
can-224	81	9	selfassembly	selfassembly	ADV
can-224	81	10	method	method	NOUN
can-224	81	11	and	and	CCONJ
can-224	81	12	membrane	membrane	NOUN
can-224	81	13	emulsion	emulsion	NOUN
can-224	81	14	interface	interface	NOUN
can-224	81	15	polymerization	polymerization	NOUN
can-224	81	16	method	method	NOUN
can-224	81	17	emulsion	emulsion	NOUN
can-224	81	18	polymerization	polymerization	NOUN
can-224	81	19	emulsion	emulsion	NOUN
can-224	81	20	polymerization	polymerization	NOUN
can-224	81	21	nucleation	nucleation	NOUN
can-224	81	22	is	be	AUX
can-224	81	23	a	a	DET
can-224	81	24	discontinuous	discontinuous	ADJ
can-224	81	25	process	process	NOUN
can-224	81	26	.	.	PUNCT
can-224	82	1	particle	particle	NOUN
can-224	82	2	size	size	NOUN
can-224	82	3	obtained	obtain	VERB
can-224	82	4	by	by	ADP
can-224	82	5	emulsion	emulsion	NOUN
can-224	82	6	polymerization	polymerization	NOUN
can-224	82	7	varies	vary	VERB
can-224	82	8	in	in	ADP
can-224	82	9	size	size	NOUN
can-224	82	10	,	,	PUNCT
can-224	82	11	typically	typically	ADV
can-224	82	12	between	between	ADP
can-224	82	13	100	100	NUM
can-224	82	14	nm	nm	ADJ
can-224	82	15	and	and	CCONJ
can-224	82	16	several	several	ADJ
can-224	82	17	ums	um	NOUN
can-224	82	18	.	.	PUNCT
can-224	83	1	c.	c.	PROPN
can-224	83	2	chauvierre	chauvierre	PROPN
can-224	83	3	,	,	PUNCT
can-224	83	4	c.	c.	PROPN
can-224	83	5	v	v	PROPN
can-224	83	6	authier	authier	NOUN
can-224	83	7	,	,	PUNCT
can-224	83	8	d.	d.	PROPN
can-224	83	9	labarre	labarre	PROPN
can-224	83	10	et	et	PROPN
can-224	83	11	al	al	PROPN
can-224	83	12	.	.	PUNCT
can-224	84	1	[	[	X
can-224	84	2	14	14	NUM
can-224	84	3	]	]	PUNCT
can-224	84	4	with	with	ADP
can-224	84	5	dextran	dextran	NOUN
can-224	84	6	,	,	PUNCT
can-224	84	7	dextran	dextran	VERB
can-224	84	8	coated	coat	VERB
can-224	84	9	polyisobutylcyanoacrylate	polyisobutylcyanoacrylate	ADJ
can-224	84	10	nanoparticles	nanoparticle	NOUN
can-224	84	11	synthesized	synthesize	VERB
can-224	84	12	by	by	ADP
can-224	84	13	anionic	anionic	ADJ
can-224	84	14	polymerization	polymerization	NOUN
can-224	84	15	and	and	CCONJ
can-224	84	16	two	two	NUM
can-224	84	17	mechanisms	mechanism	NOUN
can-224	84	18	of	of	ADP
can-224	84	19	emulsion	emulsion	NOUN
can-224	84	20	radical	radical	ADJ
can-224	84	21	polymerization	polymerization	NOUN
can-224	84	22	.	.	PUNCT
can-224	85	1	the	the	DET
can-224	85	2	self	self	NOUN
can-224	85	3	-	-	PUNCT
can-224	85	4	assembly	assembly	NOUN
can-224	85	5	polymer	polymer	NOUN
can-224	85	6	nanocomposite	nanocomposite	NOUN
can-224	85	7	has	have	VERB
can-224	85	8	a	a	DET
can-224	85	9	core	core	ADJ
can-224	85	10	-	-	PUNCT
can-224	85	11	shell	shell	NOUN
can-224	85	12	structure	structure	NOUN
can-224	85	13	by	by	ADP
can-224	85	14	dissolving	dissolve	VERB
can-224	85	15	the	the	DET
can-224	85	16	amphiphilic	amphiphilic	ADJ
can-224	85	17	polymer	polymer	NOUN
can-224	85	18	in	in	ADP
can-224	85	19	an	an	DET
can-224	85	20	organic	organic	ADJ
can-224	85	21	solvent	solvent	NOUN
can-224	85	22	and	and	CCONJ
can-224	85	23	adding	add	VERB
can-224	85	24	water	water	NOUN
can-224	85	25	to	to	PART
can-224	85	26	form	form	VERB
can-224	85	27	an	an	DET
can-224	85	28	emulsion	emulsion	NOUN
can-224	85	29	.	.	PUNCT
can-224	86	1	the	the	DET
can-224	86	2	organic	organic	ADJ
can-224	86	3	solvent	solvent	NOUN
can-224	86	4	is	be	AUX
can-224	86	5	removed	remove	VERB
can-224	86	6	by	by	ADP
can-224	86	7	vacuum	vacuum	NOUN
can-224	86	8	distillation	distillation	NOUN
can-224	86	9	or	or	CCONJ
can-224	86	10	solvent	solvent	NOUN
can-224	86	11	diff	diff	NOUN
can-224	86	12	usion	usion	NOUN
can-224	86	13	.	.	PUNCT
can-224	87	1	y.	y.	PROPN
can-224	87	2	li	li	PROPN
can-224	87	3	,	,	PUNCT
can-224	87	4	s.	s.	PROPN
can-224	87	5	ikeda	ikeda	PROPN
can-224	87	6	,	,	PUNCT
can-224	87	7	k.	k.	PROPN
can-224	87	8	nakashima	nakashima	PROPN
can-224	87	9	,	,	PUNCT
can-224	88	1	h.	h.	PROPN
can-224	88	2	nakamura	nakamura	PROPN
can-224	88	3	et	et	PROPN
can-224	88	4	al	al	PROPN
can-224	88	5	.	.	PROPN
can-224	88	6	prepared	prepare	VERB
can-224	88	7	polymethyl	polymethyl	PROPN
can-224	88	8	methacrylate	methacrylate	NOUN
can-224	88	9	micelles	micelle	NOUN
can-224	88	10	,	,	PUNCT
can-224	88	11	and	and	CCONJ
can-224	88	12	have	have	VERB
can-224	88	13	a	a	DET
can-224	88	14	core	core	ADJ
can-224	88	15	-	-	PUNCT
can-224	88	16	shell	shell	NOUN
can-224	88	17	structure	structure	NOUN
can-224	88	18	.	.	PUNCT
can-224	89	1	membrane	membrane	NOUN
can-224	89	2	emulsification	emulsification	NOUN
can-224	89	3	interface	interface	NOUN
can-224	89	4	polymerization	polymerization	NOUN
can-224	89	5	membrane	membrane	NOUN
can-224	89	6	emulsification	emulsification	NOUN
can-224	89	7	interface	interface	NOUN
can-224	89	8	is	be	AUX
can-224	89	9	a	a	DET
can-224	89	10	special	special	ADJ
can-224	89	11	interfacial	interfacial	ADJ
can-224	89	12	polymerization	polymerization	NOUN
can-224	89	13	that	that	PRON
can-224	89	14	occurs	occur	VERB
can-224	89	15	by	by	ADP
can-224	89	16	the	the	DET
can-224	89	17	addition	addition	NOUN
can-224	89	18	of	of	ADP
can-224	89	19	an	an	DET
can-224	89	20	initiator	initiator	NOUN
can-224	89	21	to	to	ADP
can-224	89	22	the	the	DET
can-224	89	23	uniform	uniform	ADJ
can-224	89	24	emulsion	emulsion	NOUN
can-224	89	25	prepared	prepare	VERB
can-224	89	26	in	in	ADP
can-224	89	27	the	the	DET
can-224	89	28	nano	nano	ADJ
can-224	89	29	porous	porous	ADJ
can-224	89	30	membrane	membrane	NOUN
can-224	89	31	.	.	PUNCT
can-224	90	1	membrane	membrane	NOUN
can-224	90	2	emulsifi	emulsifi	NOUN
can-224	90	3	cation	cation	NOUN
can-224	90	4	can	can	AUX
can-224	90	5	not	not	PART
can-224	90	6	only	only	ADV
can-224	90	7	obtain	obtain	VERB
can-224	90	8	a	a	DET
can-224	90	9	monodisperse	monodisperse	NOUN
can-224	90	10	,	,	PUNCT
can-224	90	11	stable	stable	ADJ
can-224	90	12	emulsion	emulsion	NOUN
can-224	90	13	by	by	ADP
can-224	90	14	a	a	DET
can-224	90	15	simple	simple	ADJ
can-224	90	16	and	and	CCONJ
can-224	90	17	eff	eff	PROPN
can-224	90	18	ective	ective	ADJ
can-224	90	19	method	method	NOUN
can-224	90	20	,	,	PUNCT
can-224	90	21	but	but	CCONJ
can-224	90	22	also	also	ADV
can-224	90	23	an	an	DET
can-224	90	24	eff	eff	PROPN
can-224	90	25	ective	ective	ADJ
can-224	90	26	means	mean	NOUN
can-224	90	27	of	of	ADP
can-224	90	28	preparing	prepare	VERB
can-224	90	29	functional	functional	ADJ
can-224	90	30	microspheres	microsphere	NOUN
can-224	90	31	and	and	CCONJ
can-224	90	32	microcapsules	microcapsule	NOUN
can-224	90	33	.	.	PUNCT
can-224	91	1	3.3	3.3	NUM
can-224	91	2	.	.	PUNCT
can-224	92	1	micro	micro	ADJ
can-224	92	2	emulsion	emulsion	NOUN
can-224	92	3	method	method	NOUN
can-224	92	4	there	there	PRON
can-224	92	5	is	be	VERB
can-224	92	6	a	a	DET
can-224	92	7	fundamental	fundamental	ADJ
can-224	92	8	diff	diff	NOUN
can-224	92	9	erence	erence	NOUN
can-224	92	10	between	between	ADP
can-224	92	11	the	the	DET
can-224	92	12	micro	micro	ADJ
can-224	92	13	emulsion	emulsion	NOUN
can-224	92	14	and	and	CCONJ
can-224	92	15	the	the	DET
can-224	92	16	emulsion	emulsion	NOUN
can-224	92	17	.	.	PUNCT
can-224	93	1	in	in	ADP
can-224	93	2	the	the	DET
can-224	93	3	thermodynamic	thermodynamic	ADJ
can-224	93	4	stability	stability	NOUN
can-224	93	5	conditions	condition	NOUN
can-224	93	6	can	can	AUX
can-224	93	7	be	be	AUX
can-224	93	8	spontaneously	spontaneously	ADV
can-224	93	9	formed	form	VERB
can-224	93	10	transparent	transparent	ADJ
can-224	93	11	or	or	CCONJ
can-224	93	12	translucent	translucent	ADJ
can-224	93	13	micro	micro	ADJ
can-224	93	14	emulsion	emulsion	NOUN
can-224	93	15	dispersion	dispersion	NOUN
can-224	93	16	system	system	NOUN
can-224	93	17	.	.	PUNCT
can-224	94	1	but	but	CCONJ
can-224	94	2	the	the	DET
can-224	94	3	eff	eff	PROPN
can-224	94	4	ect	ect	PROPN
can-224	94	5	is	be	AUX
can-224	94	6	not	not	PART
can-224	94	7	stable	stable	ADJ
can-224	94	8	,	,	PUNCT
can-224	94	9	placed	place	VERB
can-224	94	10	for	for	ADP
can-224	94	11	a	a	DET
can-224	94	12	period	period	NOUN
can-224	94	13	of	of	ADP
can-224	94	14	time	time	NOUN
can-224	94	15	will	will	AUX
can-224	94	16	automatically	automatically	ADV
can-224	94	17	stratify	stratify	VERB
can-224	94	18	.	.	PUNCT
can-224	95	1	the	the	DET
can-224	95	2	micro	micro	ADJ
can-224	95	3	emulsion	emulsion	NOUN
can-224	95	4	can	can	AUX
can-224	95	5	form	form	VERB
can-224	95	6	nano	nano	NOUN
can-224	95	7	cells	cell	NOUN
can-224	95	8	,	,	PUNCT
can-224	95	9	and	and	CCONJ
can-224	95	10	if	if	SCONJ
can-224	95	11	the	the	DET
can-224	95	12	reaction	reaction	NOUN
can-224	95	13	is	be	AUX
can-224	95	14	carried	carry	VERB
can-224	95	15	out	out	ADP
can-224	95	16	in	in	ADP
can-224	95	17	the	the	DET
can-224	95	18	reaction	reaction	NOUN
can-224	95	19	pool	pool	NOUN
can-224	95	20	,	,	PUNCT
can-224	95	21	the	the	DET
can-224	95	22	reaction	reaction	NOUN
can-224	95	23	product	product	NOUN
can-224	95	24	can	can	AUX
can-224	95	25	be	be	AUX
can-224	95	26	regarded	regard	VERB
can-224	95	27	as	as	ADP
can-224	95	28	nano	nano	NOUN
can-224	95	29	.	.	PUNCT
can-224	96	1	moreover	moreover	ADV
can-224	96	2	,	,	PUNCT
can-224	96	3	the	the	DET
can-224	96	4	micro	micro	ADJ
can-224	96	5	emulsion	emulsion	NOUN
can-224	96	6	reaction	reaction	NOUN
can-224	96	7	conditions	condition	NOUN
can-224	96	8	are	be	AUX
can-224	96	9	very	very	ADV
can-224	96	10	mild	mild	ADJ
can-224	96	11	,	,	PUNCT
can-224	96	12	by	by	ADP
can-224	96	13	changing	change	VERB
can-224	96	14	the	the	DET
can-224	96	15	micro	micro	ADJ
can-224	96	16	emulsion	emulsion	NOUN
can-224	96	17	preparation	preparation	NOUN
can-224	96	18	method	method	NOUN
can-224	96	19	,	,	PUNCT
can-224	96	20	the	the	DET
can-224	96	21	external	external	ADJ
can-224	96	22	conditions	condition	NOUN
can-224	96	23	change	change	VERB
can-224	96	24	more	more	ADV
can-224	96	25	so	so	SCONJ
can-224	96	26	that	that	SCONJ
can-224	96	27	it	it	PRON
can-224	96	28	changes	change	VERB
can-224	96	29	,	,	PUNCT
can-224	96	30	the	the	DET
can-224	96	31	small	small	ADJ
can-224	96	32	pool	pool	NOUN
can-224	96	33	to	to	PART
can-224	96	34	change	change	VERB
can-224	96	35	the	the	DET
can-224	96	36	shape	shape	NOUN
can-224	96	37	,	,	PUNCT
can-224	96	38	the	the	DET
can-224	96	39	product	product	NOUN
can-224	96	40	of	of	ADP
can-224	96	41	the	the	DET
can-224	96	42	nano	nano	NOUN
can-224	96	43	-	-	PUNCT
can-224	96	44	structure	structure	NOUN
can-224	96	45	is	be	AUX
can-224	96	46	diff	diff	NOUN
can-224	96	47	erent	erent	NOUN
can-224	96	48	.	.	PUNCT
can-224	97	1	the	the	DET
can-224	97	2	most	most	ADV
can-224	97	3	attractive	attractive	ADJ
can-224	97	4	is	be	AUX
can-224	97	5	the	the	DET
can-224	97	6	micro	micro	ADJ
can-224	97	7	emulsion	emulsion	NOUN
can-224	97	8	,	,	PUNCT
can-224	97	9	which	which	PRON
can-224	97	10	can	can	AUX
can-224	97	11	dissolve	dissolve	VERB
can-224	97	12	a	a	DET
can-224	97	13	large	large	ADJ
can-224	97	14	amount	amount	NOUN
can-224	97	15	of	of	ADP
can-224	97	16	water	water	NOUN
can-224	97	17	and	and	CCONJ
can-224	97	18	a	a	DET
can-224	97	19	large	large	ADJ
can-224	97	20	amount	amount	NOUN
can-224	97	21	of	of	ADP
can-224	97	22	oil	oil	NOUN
can-224	97	23	at	at	ADP
can-224	97	24	the	the	DET
can-224	97	25	same	same	ADJ
can-224	97	26	time	time	NOUN
can-224	97	27	.	.	PUNCT
can-224	98	1	it	it	PRON
can-224	98	2	can	can	AUX
can-224	98	3	make	make	VERB
can-224	98	4	the	the	DET
can-224	98	5	above	above	ADJ
can-224	98	6	oil	oil	NOUN
can-224	98	7	-	-	PUNCT
can-224	98	8	soluble	soluble	ADJ
can-224	98	9	substances	substance	NOUN
can-224	98	10	and	and	CCONJ
can-224	98	11	water	water	NOUN
can-224	98	12	-	-	PUNCT
can-224	98	13	soluble	soluble	ADJ
can-224	98	14	substances	substance	NOUN
can-224	98	15	fully	fully	ADV
can-224	98	16	mixed	mix	VERB
can-224	98	17	,	,	PUNCT
can-224	98	18	which	which	PRON
can-224	98	19	greatly	greatly	ADV
can-224	98	20	improves	improve	VERB
can-224	98	21	the	the	DET
can-224	98	22	effi	effi	PROPN
can-224	98	23	ciency	ciency	NOUN
can-224	98	24	of	of	ADP
can-224	98	25	the	the	DET
can-224	98	26	reaction	reaction	NOUN
can-224	98	27	.	.	PUNCT
can-224	99	1	at	at	ADP
can-224	99	2	present	present	ADJ
can-224	99	3	,	,	PUNCT
can-224	99	4	micro	micro	ADJ
can-224	99	5	emulsion	emulsion	NOUN
can-224	99	6	method	method	NOUN
can-224	99	7	has	have	VERB
can-224	99	8	many	many	ADJ
can-224	99	9	people	people	NOUN
can-224	99	10	at	at	ADP
can-224	99	11	home	home	ADV
can-224	99	12	and	and	CCONJ
can-224	99	13	abroad	abroad	ADV
can-224	99	14	to	to	PART
can-224	99	15	study	study	VERB
can-224	99	16	,	,	PUNCT
can-224	99	17	according	accord	VERB
can-224	99	18	to	to	ADP
can-224	99	19	the	the	DET
can-224	99	20	type	type	NOUN
can-224	99	21	of	of	ADP
can-224	99	22	micro	micro	NOUN
can-224	99	23	emulsion	emulsion	NOUN
can-224	99	24	can	can	AUX
can-224	99	25	be	be	AUX
can-224	99	26	divided	divide	VERB
can-224	99	27	into	into	ADP
can-224	99	28	normal	normal	ADJ
can-224	99	29	phase	phase	NOUN
can-224	99	30	micro	micro	NOUN
can-224	99	31	emulsion	emulsion	NOUN
can-224	99	32	(	(	PUNCT
can-224	99	33	o	o	NOUN
can-224	99	34	/	/	SYM
can-224	99	35	w	w	NOUN
can-224	99	36	)	)	PUNCT
can-224	100	1	[	[	X
can-224	100	2	15	15	NUM
can-224	100	3	]	]	PUNCT
can-224	100	4	and	and	CCONJ
can-224	100	5	reverse	reverse	ADJ
can-224	100	6	micro	micro	NOUN
can-224	100	7	emulsion	emulsion	NOUN
can-224	100	8	(	(	PUNCT
can-224	100	9	w/o	w/o	PROPN
can-224	100	10	)	)	PUNCT
can-224	101	1	[	[	X
can-224	101	2	16	16	NUM
can-224	101	3	]	]	PUNCT
can-224	101	4	.	.	PUNCT
can-224	102	1	3.4	3.4	NUM
can-224	102	2	.	.	PUNCT
can-224	102	3	ultrasonic	ultrasonic	ADJ
can-224	102	4	method	method	NOUN
can-224	102	5	liquid	liquid	ADJ
can-224	102	6	phase	phase	NOUN
can-224	102	7	internal	internal	ADJ
can-224	102	8	molecules	molecule	NOUN
can-224	102	9	in	in	ADP
can-224	102	10	the	the	DET
can-224	102	11	ultrasonic	ultrasonic	ADJ
can-224	102	12	vibration	vibration	NOUN
can-224	102	13	occurs	occur	VERB
can-224	102	14	,	,	PUNCT
can-224	102	15	the	the	DET
can-224	102	16	molecules	molecule	NOUN
can-224	102	17	change	change	VERB
can-224	102	18	,	,	PUNCT
can-224	102	19	when	when	SCONJ
can-224	102	20	the	the	DET
can-224	102	21	intensity	intensity	NOUN
can-224	102	22	of	of	ADP
can-224	102	23	ultrasound	ultrasound	NOUN
can-224	102	24	to	to	ADP
can-224	102	25	a	a	DET
can-224	102	26	certain	certain	ADJ
can-224	102	27	extent	extent	NOUN
can-224	102	28	,	,	PUNCT
can-224	102	29	will	will	AUX
can-224	102	30	produce	produce	VERB
can-224	102	31	holes	hole	NOUN
can-224	102	32	or	or	CCONJ
can-224	102	33	cavitation	cavitation	NOUN
can-224	102	34	bubble	bubble	NOUN
can-224	102	35	liquid	liquid	ADJ
can-224	102	36	molecules	molecule	NOUN
can-224	102	37	,	,	PUNCT
can-224	102	38	this	this	DET
can-224	102	39	phenomenon	phenomenon	NOUN
can-224	102	40	is	be	AUX
can-224	102	41	called	call	VERB
can-224	102	42	ultrasonic	ultrasonic	ADJ
can-224	102	43	cavitation	cavitation	NOUN
can-224	102	44	technology	technology	NOUN
can-224	102	45	[	[	X
can-224	102	46	17	17	NUM
can-224	102	47	]	]	PUNCT
can-224	102	48	.	.	PUNCT
can-224	103	1	cavitation	cavitation	NOUN
can-224	103	2	bubbles	bubble	NOUN
can-224	103	3	continue	continue	VERB
can-224	103	4	to	to	PART
can-224	103	5	produce	produce	VERB
can-224	103	6	and	and	CCONJ
can-224	103	7	violate	violate	VERB
can-224	103	8	the	the	DET
can-224	103	9	collapse	collapse	NOUN
can-224	103	10	,	,	PUNCT
can-224	103	11	when	when	SCONJ
can-224	103	12	the	the	DET
can-224	103	13	cavitation	cavitation	NOUN
can-224	103	14	bubble	bubble	NOUN
can-224	103	15	collapse	collapse	NOUN
can-224	103	16	,	,	PUNCT
can-224	103	17	resulting	result	VERB
can-224	103	18	in	in	ADP
can-224	103	19	local	local	ADJ
can-224	103	20	high	high	ADJ
can-224	103	21	temperature	temperature	NOUN
can-224	103	22	and	and	CCONJ
can-224	103	23	high	high	ADJ
can-224	103	24	pressure	pressure	NOUN
can-224	103	25	,	,	PUNCT
can-224	103	26	temperature	temperature	NOUN
can-224	103	27	changes	change	NOUN
can-224	103	28	,	,	PUNCT
can-224	103	29	and	and	CCONJ
can-224	103	30	accompanied	accompany	VERB
can-224	103	31	by	by	ADP
can-224	103	32	a	a	DET
can-224	103	33	strong	strong	ADJ
can-224	103	34	impact	impact	NOUN
can-224	103	35	and	and	CCONJ
can-224	103	36	a	a	DET
can-224	103	37	400	400	NUM
can-224	103	38	km	km	NOUN
can-224	103	39	projection	projection	NOUN
can-224	103	40	rate	rate	NOUN
can-224	103	41	.	.	PUNCT
can-224	104	1	therefore	therefore	ADV
can-224	104	2	,	,	PUNCT
can-224	104	3	ultrasonic	ultrasonic	ADJ
can-224	104	4	cavitation	cavitation	NOUN
can-224	104	5	has	have	VERB
can-224	104	6	a	a	DET
can-224	104	7	very	very	ADV
can-224	104	8	special	special	ADJ
can-224	104	9	physical	physical	ADJ
can-224	104	10	and	and	CCONJ
can-224	104	11	chemical	chemical	NOUN
can-224	104	12	environment	environment	NOUN
can-224	104	13	,	,	PUNCT
can-224	104	14	through	through	ADP
can-224	104	15	its	its	PRON
can-224	104	16	conditions	condition	NOUN
can-224	104	17	to	to	PART
can-224	104	18	achieve	achieve	VERB
can-224	104	19	some	some	DET
can-224	104	20	special	special	ADJ
can-224	104	21	chemical	chemical	NOUN
can-224	104	22	reactions	reaction	NOUN
can-224	104	23	.	.	PUNCT
can-224	105	1	for	for	ADP
can-224	105	2	example	example	NOUN
can-224	105	3	,	,	PUNCT
can-224	105	4	the	the	DET
can-224	105	5	phacoemulsifi	phacoemulsifi	PROPN
can-224	105	6	cation	cation	NOUN
can-224	105	7	on	on	ADP
can-224	105	8	a	a	DET
can-224	105	9	two	two	NUM
can-224	105	10	-	-	PUNCT
can-224	105	11	phase	phase	NOUN
can-224	105	12	liquid	liquid	ADJ
can-224	105	13	interface	interface	NOUN
can-224	105	14	can	can	AUX
can-224	105	15	cause	cause	VERB
can-224	105	16	the	the	DET
can-224	105	17	reaction	reaction	NOUN
can-224	105	18	even	even	ADV
can-224	105	19	in	in	ADP
can-224	105	20	the	the	DET
can-224	105	21	absence	absence	NOUN
can-224	105	22	of	of	ADP
can-224	105	23	a	a	DET
can-224	105	24	catalyst	catalyst	NOUN
can-224	105	25	.	.	PUNCT
can-224	106	1	now	now	ADV
can-224	106	2	a	a	DET
can-224	106	3	lot	lot	NOUN
can-224	106	4	of	of	ADP
can-224	106	5	polymerization	polymerization	NOUN
can-224	106	6	advances	advance	NOUN
can-224	106	7	in	in	ADP
can-224	106	8	synthesis	synthesis	NOUN
can-224	106	9	and	and	CCONJ
can-224	106	10	application	application	NOUN
can-224	106	11	of	of	ADP
can-224	106	12	nanometer	nanometer	NOUN
can-224	106	13	drug	drug	NOUN
can-224	106	14	carriers	carrier	NOUN
can-224	106	15	16	16	NUM
can-224	106	16	reactions	reaction	NOUN
can-224	106	17	are	be	AUX
can-224	106	18	used	use	VERB
can-224	106	19	in	in	ADP
can-224	106	20	ultrasonic	ultrasonic	ADJ
can-224	106	21	technology	technology	NOUN
can-224	106	22	.	.	PUNCT
can-224	107	1	by	by	ADP
can-224	107	2	exploring	explore	VERB
can-224	107	3	the	the	DET
can-224	107	4	preparation	preparation	NOUN
can-224	107	5	of	of	ADP
can-224	107	6	drug	drug	NOUN
can-224	107	7	carriers	carrier	NOUN
can-224	107	8	under	under	ADP
can-224	107	9	ultrasonic	ultrasonic	ADJ
can-224	107	10	conditions	condition	NOUN
can-224	107	11	,	,	PUNCT
can-224	107	12	many	many	ADJ
can-224	107	13	methods	method	NOUN
can-224	107	14	have	have	AUX
can-224	107	15	been	be	AUX
can-224	107	16	improved	improve	VERB
can-224	107	17	and	and	CCONJ
can-224	107	18	a	a	DET
can-224	107	19	better	well	ADJ
can-224	107	20	performance	performance	NOUN
can-224	107	21	nanometer	nanometer	NOUN
can-224	107	22	drug	drug	NOUN
can-224	107	23	carrier	carrier	NOUN
can-224	107	24	has	have	AUX
can-224	107	25	been	be	AUX
can-224	107	26	prepared	prepare	VERB
can-224	107	27	.	.	PUNCT
can-224	108	1	3.5	3.5	NUM
can-224	108	2	.	.	PUNCT
can-224	108	3	dialysis	dialysis	NOUN
can-224	108	4	and	and	CCONJ
can-224	108	5	solvent	solvent	NOUN
can-224	108	6	evaporation	evaporation	NOUN
can-224	108	7	method	method	NOUN
can-224	108	8	the	the	DET
can-224	108	9	drug	drug	NOUN
can-224	108	10	carrier	carrier	NOUN
can-224	108	11	is	be	AUX
can-224	108	12	dissolved	dissolve	VERB
can-224	108	13	,	,	PUNCT
can-224	108	14	the	the	DET
can-224	108	15	resulting	result	VERB
can-224	108	16	solution	solution	NOUN
can-224	108	17	is	be	AUX
can-224	108	18	dispersed	disperse	VERB
can-224	108	19	,	,	PUNCT
can-224	108	20	evaporated	evaporate	VERB
can-224	108	21	or	or	CCONJ
can-224	108	22	dialyzed	dialyze	VERB
can-224	108	23	into	into	ADP
can-224	108	24	an	an	DET
can-224	108	25	organic	organic	ADJ
can-224	108	26	solvent	solvent	NOUN
can-224	108	27	,	,	PUNCT
can-224	108	28	and	and	CCONJ
can-224	108	29	the	the	DET
can-224	108	30	drug	drug	NOUN
can-224	108	31	or	or	CCONJ
can-224	108	32	carrier	carrier	NOUN
can-224	108	33	is	be	AUX
can-224	108	34	nucleated	nucleate	VERB
can-224	108	35	and	and	CCONJ
can-224	108	36	aggregated	aggregate	VERB
can-224	108	37	due	due	ADJ
can-224	108	38	to	to	PART
can-224	108	39	drastically	drastically	ADV
can-224	108	40	reduced	reduce	VERB
can-224	108	41	solubility	solubility	NOUN
can-224	108	42	.	.	PUNCT
can-224	109	1	z.	z.	PROPN
can-224	109	2	yan	yan	PROPN
can-224	109	3	et	et	PROPN
can-224	109	4	al	al	PROPN
can-224	109	5	.	.	PUNCT
can-224	110	1	the	the	DET
can-224	110	2	preparation	preparation	NOUN
can-224	110	3	of	of	ADP
can-224	110	4	methoxypolyethylene	methoxypolyethylene	ADJ
can-224	110	5	glycol	glycol	NOUN
can-224	110	6	-	-	PUNCT
can-224	110	7	polylactic	polylactic	ADJ
can-224	110	8	acid	acid	NOUN
can-224	110	9	copolymer	copolymer	NOUN
can-224	110	10	nanoparticles	nanoparticle	NOUN
can-224	110	11	by	by	ADP
can-224	110	12	phase	phase	NOUN
can-224	110	13	separation	separation	NOUN
can-224	110	14	/	/	SYM
can-224	110	15	dialysis	dialysis	NOUN
can-224	110	16	method	method	NOUN
can-224	110	17	and	and	CCONJ
can-224	110	18	the	the	DET
can-224	110	19	study	study	NOUN
can-224	110	20	on	on	ADP
can-224	110	21	the	the	DET
can-224	110	22	distribution	distribution	NOUN
can-224	110	23	of	of	ADP
can-224	110	24	drugs	drug	NOUN
can-224	110	25	in	in	ADP
can-224	110	26	the	the	DET
can-224	110	27	nose	nose	NOUN
can-224	110	28	.	.	PUNCT
can-224	111	1	(	(	PUNCT
can-224	111	2	tp	tp	NOUN
can-224	111	3	-	-	PUNCT
can-224	111	4	pla	pla	NOUN
can-224	111	5	-	-	PUNCT
can-224	111	6	np	np	NOUN
can-224	111	7	)	)	PUNCT
can-224	111	8	,	,	PUNCT
can-224	111	9	tp	tp	NOUN
can-224	111	10	-	-	PUNCT
can-224	111	11	pla	pla	NOUN
can-224	111	12	-	-	PUNCT
can-224	111	13	the	the	DET
can-224	111	14	average	average	ADJ
can-224	111	15	particle	particle	NOUN
can-224	111	16	size	size	NOUN
can-224	111	17	of	of	ADP
can-224	111	18	np	np	PRON
can-224	111	19	was	be	AUX
can-224	111	20	determined	determine	VERB
can-224	111	21	by	by	ADP
can-224	111	22	dynamic	dynamic	ADJ
can-224	111	23	laser	laser	NOUN
can-224	111	24	particle	particle	NOUN
can-224	111	25	size	size	NOUN
can-224	111	26	analyzer	analyzer	NOUN
can-224	111	27	(	(	PUNCT
can-224	111	28	167	167	NUM
can-224	111	29	nm	nm	NOUN
can-224	111	30	)	)	PUNCT
can-224	111	31	.	.	PUNCT
can-224	112	1	the	the	DET
can-224	112	2	results	result	NOUN
can-224	112	3	showed	show	VERB
can-224	112	4	that	that	SCONJ
can-224	112	5	tp	tp	NOUN
can-224	112	6	-	-	PUNCT
can-224	112	7	pla	pla	NOUN
can-224	112	8	-	-	PUNCT
can-224	112	9	np	np	NOUN
can-224	112	10	as	as	ADP
can-224	112	11	a	a	DET
can-224	112	12	nano	nano	NOUN
can-224	112	13	-	-	PUNCT
can-224	112	14	carrier	carrier	NOUN
can-224	112	15	can	can	AUX
can-224	112	16	signifi	signifi	VERB
can-224	112	17	cantly	cantly	ADV
can-224	112	18	reduce	reduce	VERB
can-224	112	19	the	the	DET
can-224	112	20	toxicity	toxicity	NOUN
can-224	112	21	of	of	ADP
can-224	112	22	tripterygium	tripterygium	NOUN
can-224	112	23	wilfordii	wilfordii	NOUN
can-224	112	24	.	.	PUNCT
can-224	113	1	3.6	3.6	NUM
can-224	113	2	.	.	PUNCT
can-224	114	1	precipitation	precipitation	NOUN
can-224	114	2	method	method	VERB
can-224	114	3	the	the	DET
can-224	114	4	product	product	NOUN
can-224	114	5	is	be	AUX
can-224	114	6	precipitated	precipitate	VERB
can-224	114	7	in	in	ADP
can-224	114	8	solution	solution	NOUN
can-224	114	9	by	by	ADP
can-224	114	10	chemical	chemical	ADJ
can-224	114	11	reaction	reaction	NOUN
can-224	114	12	,	,	PUNCT
can-224	114	13	and	and	CCONJ
can-224	114	14	the	the	DET
can-224	114	15	size	size	NOUN
can-224	114	16	of	of	ADP
can-224	114	17	nano	nano	NOUN
can-224	114	18	-	-	PUNCT
can-224	114	19	drug	drug	NOUN
can-224	114	20	particle	particle	NOUN
can-224	114	21	size	size	NOUN
can-224	114	22	is	be	AUX
can-224	114	23	aff	aff	PROPN
can-224	114	24	ected	ecte	VERB
can-224	114	25	by	by	ADP
can-224	114	26	the	the	DET
can-224	114	27	reaction	reaction	NOUN
can-224	114	28	conditions	condition	NOUN
can-224	114	29	.	.	PUNCT
can-224	115	1	y.	y.	PROPN
can-224	115	2	wu	wu	PROPN
can-224	116	1	and	and	CCONJ
can-224	116	2	so	so	ADV
can-224	116	3	on	on	ADV
can-224	116	4	in	in	ADP
can-224	116	5	the	the	DET
can-224	116	6	preparation	preparation	NOUN
can-224	116	7	of	of	ADP
can-224	116	8	nano	nano	NOUN
can-224	116	9	-	-	PUNCT
can-224	116	10	magnetic	magnetic	ADJ
can-224	116	11	materials	material	NOUN
can-224	116	12	used	use	VERB
can-224	116	13	in	in	ADP
can-224	116	14	the	the	DET
can-224	116	15	method	method	NOUN
can-224	116	16	.	.	PUNCT
can-224	117	1	pillar	pillar	NOUN
can-224	117	2	calvo	calvo	NOUN
can-224	118	1	[	[	X
can-224	118	2	18	18	NUM
can-224	118	3	]	]	PUNCT
can-224	118	4	used	use	VERB
can-224	118	5	an	an	DET
can-224	118	6	interfacial	interfacial	ADJ
can-224	118	7	deposition	deposition	NOUN
can-224	118	8	method	method	NOUN
can-224	118	9	to	to	PART
can-224	118	10	prepare	prepare	VERB
can-224	118	11	chitosan	chitosan	NOUN
can-224	118	12	and	and	CCONJ
can-224	118	13	polyline	polyline	NOUN
can-224	118	14	-	-	PUNCT
can-224	118	15	coated	coat	VERB
can-224	118	16	nano	nano	NOUN
can-224	118	17	capsules	capsule	NOUN
can-224	118	18	to	to	PART
can-224	118	19	study	study	VERB
can-224	118	20	the	the	DET
can-224	118	21	effi	effi	PROPN
can-224	118	22	cacy	cacy	NOUN
can-224	118	23	of	of	ADP
can-224	118	24	capsules	capsule	NOUN
can-224	118	25	as	as	ADP
can-224	118	26	indomethacin	indomethacin	NOUN
can-224	118	27	.	.	PUNCT
can-224	119	1	the	the	DET
can-224	119	2	study	study	NOUN
can-224	119	3	found	find	VERB
can-224	119	4	that	that	SCONJ
can-224	119	5	the	the	DET
can-224	119	6	effi	effi	PROPN
can-224	119	7	cacy	cacy	NOUN
can-224	119	8	of	of	ADP
can-224	119	9	coated	coated	ADJ
can-224	119	10	chitosan	chitosan	NOUN
can-224	119	11	increased	increase	VERB
can-224	119	12	by	by	ADP
can-224	119	13	a	a	DET
can-224	119	14	factor	factor	NOUN
can-224	119	15	of	of	ADP
can-224	119	16	two	two	NUM
can-224	119	17	,	,	PUNCT
can-224	119	18	while	while	SCONJ
can-224	119	19	the	the	DET
can-224	119	20	effi	effi	PROPN
can-224	119	21	cacy	cacy	NOUN
can-224	119	22	of	of	ADP
can-224	119	23	coated	coat	VERB
can-224	119	24	with	with	ADP
can-224	119	25	polyline	polyline	PROPN
can-224	119	26	did	do	AUX
can-224	119	27	not	not	PART
can-224	119	28	change	change	VERB
can-224	119	29	.	.	PUNCT
can-224	120	1	4	4	X
can-224	120	2	.	.	X
can-224	120	3	application	application	NOUN
can-224	120	4	and	and	CCONJ
can-224	120	5	prospect	prospect	NOUN
can-224	120	6	of	of	ADP
can-224	120	7	nanometer	nanometer	NOUN
can-224	120	8	drug	drug	NOUN
can-224	120	9	carrier	carrier	NOUN
can-224	120	10	4.1	4.1	NUM
can-224	120	11	.	.	PUNCT
can-224	121	1	application	application	NOUN
can-224	121	2	of	of	ADP
can-224	121	3	nanometer	nanometer	NOUN
can-224	121	4	drug	drug	NOUN
can-224	121	5	carrier	carrier	NOUN
can-224	121	6	in	in	ADP
can-224	121	7	clinical	clinical	ADJ
can-224	121	8	medicine	medicine	NOUN
can-224	121	9	oral	oral	ADJ
can-224	121	10	drug	drug	NOUN
can-224	121	11	carriers	carrier	NOUN
can-224	121	12	:	:	PUNCT
can-224	121	13	drugs	drug	NOUN
can-224	121	14	and	and	CCONJ
can-224	121	15	drugs	drug	NOUN
can-224	121	16	are	be	AUX
can-224	121	17	aff	aff	AUX
can-224	121	18	ected	ecte	VERB
can-224	121	19	by	by	ADP
can-224	121	20	the	the	DET
can-224	121	21	route	route	NOUN
can-224	121	22	of	of	ADP
can-224	121	23	administration	administration	NOUN
can-224	121	24	.	.	PUNCT
can-224	122	1	oral	oral	ADJ
can-224	122	2	effi	effi	PROPN
can-224	122	3	cacy	cacy	NOUN
can-224	122	4	is	be	AUX
can-224	122	5	mainly	mainly	ADV
can-224	122	6	aff	aff	AUX
can-224	122	7	ected	ecte	VERB
can-224	122	8	by	by	ADP
can-224	122	9	two	two	NUM
can-224	122	10	primary	primary	ADJ
can-224	122	11	eff	eff	PROPN
can-224	122	12	ects	ect	NOUN
can-224	122	13	,	,	PUNCT
can-224	122	14	biogenic	biogenic	ADJ
can-224	122	15	enzymes	enzyme	NOUN
can-224	122	16	and	and	CCONJ
can-224	122	17	liver	liver	NOUN
can-224	122	18	enzymes	enzyme	NOUN
can-224	122	19	on	on	ADP
can-224	122	20	the	the	DET
can-224	122	21	gastrointestinal	gastrointestinal	ADJ
can-224	122	22	tract	tract	NOUN
can-224	122	23	that	that	PRON
can-224	122	24	are	be	AUX
can-224	122	25	epithelial	epithelial	ADJ
can-224	122	26	cells	cell	NOUN
can-224	122	27	.	.	PUNCT
can-224	123	1	many	many	ADJ
can-224	123	2	drugs	drug	NOUN
can-224	123	3	are	be	AUX
can-224	123	4	mostly	mostly	ADV
can-224	123	5	due	due	ADJ
can-224	123	6	to	to	ADP
can-224	123	7	the	the	DET
can-224	123	8	first	first	ADJ
can-224	123	9	effect	effect	NOUN
can-224	123	10	and	and	CCONJ
can-224	123	11	metabolic	metabolic	NOUN
can-224	123	12	failure	failure	NOUN
can-224	123	13	,	,	PUNCT
can-224	123	14	such	such	ADJ
can-224	123	15	as	as	ADP
can-224	123	16	peptides	peptide	NOUN
can-224	123	17	,	,	PUNCT
can-224	123	18	protein	protein	NOUN
can-224	123	19	drugs	drug	NOUN
can-224	123	20	have	have	AUX
can-224	123	21	not	not	PART
can-224	123	22	been	be	AUX
can-224	123	23	a	a	DET
can-224	123	24	good	good	ADJ
can-224	123	25	therapeutic	therapeutic	ADJ
can-224	123	26	eff	eff	PROPN
can-224	123	27	ect	ect	ADJ
can-224	123	28	,	,	PUNCT
can-224	123	29	oral	oral	ADJ
can-224	123	30	route	route	NOUN
can-224	123	31	of	of	ADP
can-224	123	32	administration	administration	NOUN
can-224	123	33	usually	usually	ADV
can-224	123	34	must	must	AUX
can-224	123	35	be	be	AUX
can-224	123	36	changed	change	VERB
can-224	123	37	to	to	ADP
can-224	123	38	intravenous	intravenous	ADJ
can-224	123	39	injection	injection	NOUN
can-224	123	40	.	.	PUNCT
can-224	124	1	as	as	SCONJ
can-224	124	2	the	the	DET
can-224	124	3	non	non	ADJ
can-224	124	4	-	-	ADJ
can-224	124	5	targeted	targeted	ADJ
can-224	124	6	drug	drug	NOUN
can-224	124	7	through	through	ADP
can-224	124	8	the	the	DET
can-224	124	9	injection	injection	NOUN
can-224	124	10	pathway	pathway	NOUN
can-224	124	11	steps	step	NOUN
can-224	124	12	can	can	AUX
can-224	124	13	be	be	AUX
can-224	124	14	evenly	evenly	ADV
can-224	124	15	distributed	distribute	VERB
can-224	124	16	in	in	ADP
can-224	124	17	the	the	DET
can-224	124	18	systemic	systemic	ADJ
can-224	124	19	blood	blood	NOUN
can-224	124	20	circulation	circulation	NOUN
can-224	124	21	,	,	PUNCT
can-224	124	22	and	and	CCONJ
can-224	124	23	then	then	ADV
can-224	124	24	reach	reach	VERB
can-224	124	25	the	the	DET
can-224	124	26	lesion	lesion	NOUN
can-224	124	27	tissue	tissue	NOUN
can-224	124	28	,	,	PUNCT
can-224	124	29	protein	protein	NOUN
can-224	124	30	binding	binding	NOUN
can-224	124	31	,	,	PUNCT
can-224	124	32	excretion	excretion	NOUN
can-224	124	33	,	,	PUNCT
can-224	124	34	degradation	degradation	NOUN
can-224	124	35	,	,	PUNCT
can-224	124	36	etc	etc	X
can-224	124	37	.	.	X
can-224	124	38	,	,	PUNCT
can-224	124	39	only	only	ADV
can-224	124	40	a	a	DET
can-224	124	41	small	small	ADJ
can-224	124	42	amount	amount	NOUN
can-224	124	43	of	of	ADP
can-224	124	44	drugs	drug	NOUN
can-224	124	45	to	to	PART
can-224	124	46	reach	reach	VERB
can-224	124	47	the	the	DET
can-224	124	48	lesion	lesion	NOUN
can-224	124	49	.	.	PUNCT
can-224	125	1	the	the	DET
can-224	125	2	purpose	purpose	NOUN
can-224	125	3	of	of	ADP
can-224	125	4	targeted	target	VERB
can-224	125	5	drug	drug	NOUN
can-224	125	6	delivery	delivery	NOUN
can-224	125	7	is	be	AUX
can-224	125	8	to	to	PART
can-224	125	9	improve	improve	VERB
can-224	125	10	the	the	DET
can-224	125	11	drug	drug	NOUN
can-224	125	12	concentration	concentration	NOUN
can-224	125	13	in	in	ADP
can-224	125	14	the	the	DET
can-224	125	15	target	target	NOUN
can-224	125	16	area	area	NOUN
can-224	125	17	and	and	CCONJ
can-224	125	18	improve	improve	VERB
can-224	125	19	the	the	DET
can-224	125	20	effi	effi	PROPN
can-224	125	21	ciency	ciency	NOUN
can-224	125	22	of	of	ADP
can-224	125	23	the	the	DET
can-224	125	24	drug	drug	NOUN
can-224	125	25	to	to	PART
can-224	125	26	reduce	reduce	VERB
can-224	125	27	the	the	DET
can-224	125	28	side	side	NOUN
can-224	125	29	eff	eff	PROPN
can-224	125	30	ects	ect	NOUN
can-224	125	31	of	of	ADP
can-224	125	32	drugs	drug	NOUN
can-224	125	33	in	in	ADP
can-224	125	34	the	the	DET
can-224	125	35	fi	fi	NOUN
can-224	125	36	eld	eld	NOUN
can-224	125	37	has	have	AUX
can-224	125	38	been	be	AUX
can-224	125	39	an	an	DET
can-224	125	40	important	important	ADJ
can-224	125	41	research	research	NOUN
can-224	125	42	topic	topic	NOUN
can-224	125	43	,	,	PUNCT
can-224	125	44	nano	nano	NOUN
can-224	125	45	-	-	PUNCT
can-224	125	46	drug	drug	NOUN
can-224	125	47	carrier	carrier	NOUN
can-224	125	48	research	research	PROPN
can-224	125	49	eff	eff	PROPN
can-224	125	50	ectively	ectively	ADV
can-224	125	51	solves	solve	VERB
can-224	125	52	these	these	DET
can-224	125	53	problems	problem	NOUN
can-224	125	54	.	.	PUNCT
can-224	126	1	after	after	SCONJ
can-224	126	2	some	some	DET
can-224	126	3	oral	oral	ADJ
can-224	126	4	medication	medication	NOUN
can-224	126	5	in	in	ADP
can-224	126	6	the	the	DET
can-224	126	7	nanoparticle	nanoparticle	NOUN
can-224	126	8	wrapped	wrap	VERB
can-224	126	9	under	under	ADP
can-224	126	10	the	the	DET
can-224	126	11	gastric	gastric	ADJ
can-224	126	12	acid	acid	NOUN
can-224	126	13	,	,	PUNCT
can-224	126	14	pepsin	pepsin	NOUN
can-224	126	15	on	on	ADP
can-224	126	16	the	the	DET
can-224	126	17	drug	drug	NOUN
can-224	126	18	decomposition	decomposition	NOUN
can-224	126	19	decreased	decrease	VERB
can-224	126	20	.	.	PUNCT
can-224	127	1	in	in	ADP
can-224	127	2	addition	addition	NOUN
can-224	127	3	,	,	PUNCT
can-224	127	4	the	the	DET
can-224	127	5	nanoparticles	nanoparticle	NOUN
can-224	127	6	can	can	AUX
can-224	127	7	easily	easily	ADV
can-224	127	8	promote	promote	VERB
can-224	127	9	the	the	DET
can-224	127	10	delivery	delivery	NOUN
can-224	127	11	of	of	ADP
can-224	127	12	drugs	drug	NOUN
can-224	127	13	with	with	ADP
can-224	127	14	poor	poor	ADJ
can-224	127	15	oral	oral	ADJ
can-224	127	16	absorption	absorption	NOUN
can-224	127	17	specifi	specifi	PROPN
can-224	127	18	city	city	PROPN
can-224	127	19	in	in	ADP
can-224	127	20	the	the	DET
can-224	127	21	human	human	ADJ
can-224	127	22	body	body	NOUN
can-224	127	23	,	,	PUNCT
can-224	127	24	prolonging	prolong	VERB
can-224	127	25	the	the	DET
can-224	127	26	action	action	NOUN
can-224	127	27	time	time	NOUN
can-224	127	28	of	of	ADP
can-224	127	29	the	the	DET
can-224	127	30	drug	drug	NOUN
can-224	127	31	,	,	PUNCT
can-224	127	32	and	and	CCONJ
can-224	127	33	cyclosporine	cyclosporine	NOUN
can-224	127	34	is	be	AUX
can-224	127	35	usually	usually	ADV
can-224	127	36	used	use	VERB
can-224	127	37	as	as	ADP
can-224	127	38	an	an	DET
can-224	127	39	anti	anti	ADJ
can-224	127	40	-	-	ADJ
can-224	127	41	rejection	rejection	ADJ
can-224	127	42	drug	drug	NOUN
can-224	127	43	in	in	ADP
can-224	127	44	clinical	clinical	ADJ
can-224	127	45	organ	organ	NOUN
can-224	127	46	transplantation	transplantation	NOUN
can-224	127	47	,	,	PUNCT
can-224	127	48	and	and	CCONJ
can-224	127	49	the	the	DET
can-224	127	50	waterslow	waterslow	ADJ
can-224	127	51	absorption	absorption	NOUN
can-224	127	52	,	,	PUNCT
can-224	127	53	oral	oral	ADJ
can-224	127	54	use	use	NOUN
can-224	127	55	of	of	ADP
can-224	127	56	low	low	ADJ
can-224	127	57	bioavailability	bioavailability	NOUN
can-224	127	58	.	.	PUNCT
can-224	128	1	anti	anti	ADJ
can-224	128	2	-	-	ADJ
can-224	128	3	tumor	tumor	ADJ
can-224	128	4	drug	drug	NOUN
can-224	128	5	carrier	carrier	NOUN
can-224	128	6	:	:	PUNCT
can-224	128	7	in	in	ADP
can-224	128	8	recent	recent	ADJ
can-224	128	9	years	year	NOUN
can-224	128	10	,	,	PUNCT
can-224	128	11	nano	nano	NOUN
can-224	128	12	-	-	PUNCT
can-224	128	13	capsule	capsule	NOUN
can-224	128	14	for	for	ADP
can-224	128	15	anti	anti	ADJ
can-224	128	16	-	-	ADJ
can-224	128	17	cancer	cancer	ADJ
can-224	128	18	drug	drug	NOUN
can-224	128	19	carrier	carrier	NOUN
can-224	128	20	particles	particle	NOUN
can-224	128	21	research	research	NOUN
can-224	128	22	has	have	AUX
can-224	128	23	become	become	VERB
can-224	128	24	the	the	DET
can-224	128	25	focus	focus	NOUN
can-224	128	26	of	of	ADP
can-224	128	27	attention	attention	NOUN
can-224	128	28	of	of	ADP
can-224	128	29	medical	medical	ADJ
can-224	128	30	workers	worker	NOUN
can-224	128	31	.	.	PUNCT
can-224	129	1	most	most	ADJ
can-224	129	2	of	of	ADP
can-224	129	3	the	the	DET
can-224	129	4	anti	anti	ADJ
can-224	129	5	-	-	ADJ
can-224	129	6	cancer	cancer	ADJ
can-224	129	7	drugs	drug	NOUN
can-224	129	8	,	,	PUNCT
can-224	129	9	in	in	ADP
can-224	129	10	the	the	DET
can-224	129	11	cancer	cancer	NOUN
can-224	129	12	treatment	treatment	NOUN
can-224	129	13	of	of	ADP
can-224	129	14	specificity	specificity	NOUN
can-224	129	15	is	be	AUX
can-224	129	16	poor	poor	ADJ
can-224	129	17	,	,	PUNCT
can-224	129	18	the	the	DET
can-224	129	19	key	key	NOUN
can-224	129	20	is	be	AUX
can-224	129	21	how	how	SCONJ
can-224	129	22	to	to	PART
can-224	129	23	target	target	VERB
can-224	129	24	the	the	DET
can-224	129	25	drug	drug	NOUN
can-224	129	26	delivery	delivery	NOUN
can-224	129	27	to	to	ADP
can-224	129	28	the	the	DET
can-224	129	29	tumor	tumor	NOUN
can-224	129	30	cells	cell	NOUN
can-224	129	31	without	without	ADP
can-224	129	32	damage	damage	NOUN
can-224	129	33	to	to	ADP
can-224	129	34	normal	normal	ADJ
can-224	129	35	cells	cell	NOUN
can-224	129	36	.	.	PUNCT
can-224	130	1	liposomes	liposome	NOUN
can-224	130	2	or	or	CCONJ
can-224	130	3	microcapsules	microcapsule	NOUN
can-224	130	4	as	as	ADP
can-224	130	5	a	a	DET
can-224	130	6	drug	drug	NOUN
can-224	130	7	carrier	carrier	NOUN
can-224	130	8	can	can	AUX
can-224	130	9	improve	improve	VERB
can-224	130	10	the	the	DET
can-224	130	11	water	water	NOUN
can-224	130	12	solubility	solubility	NOUN
can-224	130	13	of	of	ADP
can-224	130	14	drugs	drug	NOUN
can-224	130	15	,	,	PUNCT
can-224	130	16	so	so	SCONJ
can-224	130	17	that	that	SCONJ
can-224	130	18	drug	drug	NOUN
can-224	130	19	targeting	targeting	NOUN
can-224	130	20	,	,	PUNCT
can-224	130	21	reduce	reduce	VERB
can-224	130	22	drug	drug	NOUN
can-224	130	23	toxicity	toxicity	NOUN
can-224	130	24	and	and	CCONJ
can-224	130	25	prolong	prolong	VERB
can-224	130	26	the	the	DET
can-224	130	27	residence	residence	NOUN
can-224	130	28	time	time	NOUN
can-224	130	29	,	,	PUNCT
can-224	130	30	prolonged	prolong	VERB
can-224	130	31	the	the	DET
can-224	130	32	survival	survival	NOUN
can-224	130	33	time	time	NOUN
can-224	130	34	of	of	ADP
can-224	130	35	tumor	tumor	NOUN
can-224	130	36	animals	animal	NOUN
can-224	130	37	.	.	PUNCT
can-224	131	1	soma	soma	PROPN
can-224	131	2	et	et	PROPN
can-224	131	3	al	al	PROPN
can-224	131	4	.	.	PUNCT
can-224	132	1	[	[	X
can-224	132	2	19	19	NUM
can-224	132	3	]	]	PUNCT
can-224	132	4	explored	explore	VERB
can-224	132	5	the	the	DET
can-224	132	6	eff	eff	PROPN
can-224	132	7	ects	ect	NOUN
can-224	132	8	of	of	ADP
can-224	132	9	macrophages	macrophage	NOUN
can-224	132	10	on	on	ADP
can-224	132	11	the	the	DET
can-224	132	12	presence	presence	NOUN
can-224	132	13	of	of	ADP
can-224	132	14	doxorubicin	doxorubicin	PROPN
can-224	132	15	-	-	PUNCT
can-224	132	16	containing	contain	VERB
can-224	132	17	nanoparticles	nanoparticle	NOUN
can-224	132	18	,	,	PUNCT
can-224	132	19	and	and	CCONJ
can-224	132	20	the	the	DET
can-224	132	21	results	result	NOUN
can-224	132	22	showed	show	VERB
can-224	132	23	that	that	SCONJ
can-224	132	24	cancer	cancer	NOUN
can-224	132	25	cells	cell	NOUN
can-224	132	26	with	with	ADP
can-224	132	27	nanoparticles	nanoparticle	NOUN
can-224	132	28	containing	contain	VERB
can-224	132	29	doxorubicin	doxorubicin	PROPN
can-224	132	30	toxicity	toxicity	NOUN
can-224	132	31	were	be	AUX
can-224	132	32	much	much	ADV
can-224	132	33	more	more	ADV
can-224	132	34	toxic	toxic	ADJ
can-224	132	35	than	than	ADP
can-224	132	36	free	free	ADJ
can-224	132	37	doxorubicin	doxorubicin	PROPN
can-224	132	38	.	.	PUNCT
can-224	133	1	as	as	ADP
can-224	133	2	a	a	DET
can-224	133	3	new	new	ADJ
can-224	133	4	anti	anti	ADJ
can-224	133	5	-	-	ADJ
can-224	133	6	cancer	cancer	ADJ
can-224	133	7	drug	drug	NOUN
can-224	133	8	paclitaxel	paclitaxel	NOUN
can-224	133	9	encapsulated	encapsulate	VERB
can-224	133	10	in	in	ADP
can-224	133	11	pvp	pvp	NOUN
can-224	133	12	nanoparticles	nanoparticle	NOUN
can-224	133	13	in	in	ADP
can-224	133	14	vivo	vivo	ADJ
can-224	133	15	experiments	experiment	NOUN
can-224	133	16	,	,	PUNCT
can-224	133	17	the	the	DET
can-224	133	18	tumor	tumor	NOUN
can-224	133	19	size	size	NOUN
can-224	133	20	of	of	ADP
can-224	133	21	tumor	tumor	NOUN
can-224	133	22	-	-	PUNCT
can-224	133	23	bearing	bear	VERB
can-224	133	24	mice	mouse	NOUN
can-224	133	25	was	be	AUX
can-224	133	26	reduced	reduce	VERB
can-224	133	27	and	and	CCONJ
can-224	133	28	the	the	DET
can-224	133	29	survival	survival	NOUN
can-224	133	30	time	time	NOUN
can-224	133	31	was	be	AUX
can-224	133	32	evaluated	evaluate	VERB
can-224	133	33	for	for	ADP
can-224	133	34	effi	effi	PROPN
can-224	133	35	cacy	cacy	NOUN
can-224	133	36	.	.	PUNCT
can-224	134	1	the	the	DET
can-224	134	2	results	result	NOUN
can-224	134	3	showed	show	VERB
can-224	134	4	that	that	SCONJ
can-224	134	5	paclitaxel	paclitaxel	PROPN
can-224	134	6	was	be	AUX
can-224	134	7	less	less	ADJ
can-224	134	8	than	than	SCONJ
can-224	134	9	the	the	DET
can-224	134	10	free	free	ADJ
can-224	134	11	paclitaxel	paclitaxel	NOUN
can-224	134	12	nanoparticles	nanoparticle	VERB
can-224	134	13	the	the	DET
can-224	134	14	efficacy	efficacy	NOUN
can-224	134	15	of	of	ADP
can-224	134	16	the	the	DET
can-224	134	17	concentration	concentration	NOUN
can-224	134	18	was	be	AUX
can-224	134	19	significantly	significantly	ADV
can-224	134	20	increased	increase	VERB
can-224	134	21	.	.	PUNCT
can-224	135	1	the	the	DET
can-224	135	2	experiment	experiment	NOUN
can-224	135	3	also	also	ADV
can-224	135	4	prepared	prepare	VERB
can-224	135	5	a	a	DET
can-224	135	6	package	package	NOUN
can-224	135	7	of	of	ADP
can-224	135	8	plga	plga	NOUN
can-224	135	9	nanoparticles	nanoparticle	NOUN
can-224	135	10	targeting	target	VERB
can-224	135	11	drug	drug	NOUN
can-224	135	12	paclitaxel	paclitaxel	NOUN
can-224	135	13	,	,	PUNCT
can-224	135	14	as	as	ADV
can-224	135	15	well	well	ADV
can-224	135	16	as	as	ADP
can-224	135	17	linked	link	VERB
can-224	135	18	to	to	ADP
can-224	135	19	a	a	DET
can-224	135	20	specifi	specifi	PROPN
can-224	135	21	c	c	NOUN
can-224	135	22	targeting	target	VERB
can-224	135	23	malignant	malignant	ADJ
can-224	135	24	melanoma	melanoma	NOUN
can-224	135	25	,	,	PUNCT
can-224	135	26	breast	breast	NOUN
can-224	135	27	cancer	cancer	NOUN
can-224	135	28	,	,	PUNCT
can-224	135	29	mouse	mouse	NOUN
can-224	135	30	-	-	PUNCT
can-224	135	31	derived	derive	VERB
can-224	135	32	anti	anti	ADJ
can-224	135	33	-	-	ADJ
can-224	135	34	tumor	tumor	ADJ
can-224	135	35	-	-	PUNCT
can-224	135	36	related	relate	VERB
can-224	135	37	antigen	antigen	ADJ
can-224	135	38	monoclonal	monoclonal	NOUN
can-224	135	39	antibody	antibody	NOUN
can-224	135	40	sm5	sm5	PROPN
can-224	135	41	-	-	PUNCT
can-224	135	42	1	1	NUM
can-224	135	43	single	single	ADJ
can-224	135	44	chain	chain	NOUN
can-224	135	45	antibody	antibody	NOUN
can-224	135	46	,	,	PUNCT
can-224	135	47	the	the	DET
can-224	135	48	results	result	NOUN
can-224	135	49	show	show	VERB
can-224	135	50	that	that	SCONJ
can-224	135	51	it	it	PRON
can-224	135	52	can	can	AUX
can-224	135	53	be	be	AUX
can-224	135	54	designed	design	VERB
can-224	135	55	to	to	PART
can-224	135	56	kill	kill	VERB
can-224	135	57	liver	liver	NOUN
can-224	135	58	cancer	cancer	NOUN
can-224	135	59	cells	cell	NOUN
can-224	135	60	[	[	X
can-224	135	61	20	20	NUM
can-224	135	62	]	]	PUNCT
can-224	135	63	.	.	PUNCT
can-224	136	1	targeting	target	VERB
can-224	136	2	the	the	DET
can-224	136	3	carrier	carrier	NOUN
can-224	136	4	of	of	ADP
can-224	136	5	the	the	DET
can-224	136	6	brain	brain	NOUN
can-224	136	7	:	:	PUNCT
can-224	136	8	the	the	DET
can-224	136	9	presence	presence	NOUN
can-224	136	10	of	of	ADP
can-224	136	11	the	the	DET
can-224	136	12	blood	blood	NOUN
can-224	136	13	-	-	PUNCT
can-224	136	14	brain	brain	NOUN
can-224	136	15	barrier	barrier	NOUN
can-224	136	16	,	,	PUNCT
can-224	136	17	the	the	DET
can-224	136	18	usual	usual	ADJ
can-224	136	19	drug	drug	NOUN
can-224	136	20	is	be	AUX
can-224	136	21	not	not	PART
can-224	136	22	easy	easy	ADJ
can-224	136	23	to	to	PART
can-224	136	24	enter	enter	VERB
can-224	136	25	the	the	DET
can-224	136	26	brain	brain	NOUN
can-224	136	27	,	,	PUNCT
can-224	136	28	so	so	SCONJ
can-224	136	29	the	the	DET
can-224	136	30	part	part	NOUN
can-224	136	31	of	of	ADP
can-224	136	32	the	the	DET
can-224	136	33	diagnosis	diagnosis	NOUN
can-224	136	34	and	and	CCONJ
can-224	136	35	treatment	treatment	NOUN
can-224	136	36	is	be	AUX
can-224	136	37	very	very	ADV
can-224	136	38	diffi	diffi	ADJ
can-224	136	39	cult	cult	NOUN
can-224	136	40	.	.	PUNCT
can-224	137	1	studies	study	NOUN
can-224	137	2	have	have	AUX
can-224	137	3	shown	show	VERB
can-224	137	4	that	that	SCONJ
can-224	137	5	modifi	modifi	NOUN
can-224	137	6	ed	ed	PROPN
can-224	137	7	nanoparticles	nanoparticle	NOUN
can-224	137	8	can	can	AUX
can-224	137	9	pass	pass	VERB
can-224	137	10	through	through	ADP
can-224	137	11	the	the	DET
can-224	137	12	blood	blood	NOUN
can-224	137	13	-	-	PUNCT
can-224	137	14	brain	brain	NOUN
can-224	137	15	barrier	barrier	NOUN
can-224	137	16	,	,	PUNCT
can-224	137	17	which	which	PRON
can-224	137	18	acts	act	VERB
can-224	137	19	as	as	ADP
can-224	137	20	a	a	DET
can-224	137	21	drug	drug	NOUN
can-224	137	22	delivery	delivery	NOUN
can-224	137	23	to	to	ADP
can-224	137	24	the	the	DET
can-224	137	25	central	central	ADJ
can-224	137	26	nervous	nervous	ADJ
can-224	137	27	system	system	NOUN
can-224	137	28	.	.	PUNCT
can-224	138	1	camptothecin	camptothecin	PROPN
can-224	138	2	solid	solid	ADJ
can-224	138	3	lipid	lipid	NOUN
can-224	138	4	nanoparticles	nanoparticle	NOUN
can-224	138	5	were	be	AUX
can-224	138	6	injected	inject	VERB
can-224	138	7	into	into	ADP
can-224	138	8	mice	mouse	NOUN
can-224	138	9	and	and	CCONJ
can-224	138	10	found	find	VERB
can-224	138	11	that	that	SCONJ
can-224	138	12	camptothecin	camptothecin	PROPN
can-224	138	13	was	be	AUX
can-224	138	14	enriched	enrich	VERB
can-224	138	15	in	in	ADP
can-224	138	16	rat	rat	NOUN
can-224	138	17	brain	brain	NOUN
can-224	138	18	,	,	PUNCT
can-224	138	19	liver	liver	NOUN
can-224	138	20	,	,	PUNCT
can-224	138	21	heart	heart	NOUN
can-224	138	22	,	,	PUNCT
can-224	138	23	spleen	spleen	NOUN
can-224	138	24	,	,	PUNCT
can-224	138	25	brain	brain	NOUN
can-224	138	26	auc	auc	NOUN
can-224	138	27	/	/	SYM
can-224	138	28	dose	dose	PROPN
can-224	138	29	and	and	CCONJ
can-224	138	30	mrt	mrt	PROPN
can-224	138	31	increased	increase	VERB
can-224	138	32	by	by	ADP
can-224	138	33	10.4	10.4	NUM
can-224	138	34	and	and	CCONJ
can-224	138	35	4	4	NUM
can-224	138	36	times	time	NOUN
can-224	138	37	,	,	PUNCT
can-224	138	38	so	so	SCONJ
can-224	138	39	this	this	DET
can-224	138	40	nano	nano	NOUN
can-224	138	41	granules	granule	NOUN
can-224	138	42	can	can	AUX
can-224	138	43	pass	pass	VERB
can-224	138	44	the	the	DET
can-224	138	45	blood	blood	NOUN
can-224	138	46	-	-	PUNCT
can-224	138	47	brain	brain	NOUN
can-224	138	48	barrier	barrier	NOUN
can-224	138	49	,	,	PUNCT
can-224	138	50	which	which	PRON
can-224	138	51	is	be	AUX
can-224	138	52	of	of	ADP
can-224	138	53	special	special	ADJ
can-224	138	54	signifi	signifi	NOUN
can-224	138	55	cance	cance	NOUN
can-224	138	56	for	for	ADP
can-224	138	57	the	the	DET
can-224	138	58	treatment	treatment	NOUN
can-224	138	59	of	of	ADP
can-224	138	60	brain	brain	NOUN
can-224	138	61	tumors	tumor	NOUN
can-224	139	1	[	[	X
can-224	139	2	21	21	NUM
can-224	139	3	]	]	PUNCT
can-224	139	4	.	.	PUNCT
can-224	140	1	vector	vector	NOUN
can-224	140	2	is	be	AUX
can-224	140	3	a	a	DET
can-224	140	4	gene	gene	NOUN
can-224	140	5	delivery	delivery	NOUN
can-224	140	6	:	:	PUNCT
can-224	140	7	antisense	antisense	NOUN
can-224	140	8	oligonucleotide	oligonucleotide	NOUN
can-224	140	9	technology	technology	NOUN
can-224	140	10	is	be	AUX
can-224	140	11	one	one	NUM
can-224	140	12	of	of	ADP
can-224	140	13	the	the	DET
can-224	140	14	gene	gene	NOUN
can-224	140	15	therapy	therapy	NOUN
can-224	140	16	methods	method	NOUN
can-224	140	17	aimed	aim	VERB
can-224	140	18	at	at	ADP
can-224	140	19	designing	design	VERB
can-224	140	20	antisense	antisense	NOUN
can-224	140	21	nucleic	nucleic	ADJ
can-224	140	22	acids	acid	NOUN
can-224	140	23	against	against	ADP
can-224	140	24	a	a	DET
can-224	140	25	specific	specific	ADJ
can-224	140	26	target	target	NOUN
can-224	140	27	sequence	sequence	NOUN
can-224	140	28	based	base	VERB
can-224	140	29	on	on	ADP
can-224	140	30	the	the	DET
can-224	140	31	principle	principle	NOUN
can-224	140	32	of	of	ADP
can-224	140	33	nucleic	nucleic	ADJ
can-224	140	34	acid	acid	NOUN
can-224	140	35	hybridization	hybridization	NOUN
can-224	140	36	,	,	PUNCT
can-224	140	37	thereby	thereby	ADV
can-224	140	38	inhibiting	inhibit	VERB
can-224	140	39	the	the	DET
can-224	140	40	expression	expression	NOUN
can-224	140	41	of	of	ADP
can-224	140	42	a	a	DET
can-224	140	43	particular	particular	ADJ
can-224	140	44	gene	gene	NOUN
can-224	140	45	.	.	PUNCT
can-224	141	1	antisense	antisense	NOUN
can-224	141	2	oligonucleotide	oligonucleotide	NOUN
can-224	141	3	drugs	drug	NOUN
can-224	141	4	can	can	AUX
can-224	141	5	hybridize	hybridize	VERB
can-224	141	6	to	to	ADP
can-224	141	7	a	a	DET
can-224	141	8	particular	particular	ADJ
can-224	141	9	target	target	NOUN
can-224	141	10	gene	gene	NOUN
can-224	141	11	and	and	CCONJ
can-224	141	12	interfere	interfere	VERB
can-224	141	13	with	with	ADP
can-224	141	14	the	the	DET
can-224	141	15	production	production	NOUN
can-224	141	16	of	of	ADP
can-224	141	17	a	a	DET
can-224	141	18	pathogenic	pathogenic	ADJ
can-224	141	19	protein	protein	NOUN
can-224	141	20	at	at	ADP
can-224	141	21	the	the	DET
can-224	141	22	gene	gene	NOUN
can-224	141	23	level	level	NOUN
can-224	141	24	.	.	PUNCT
can-224	142	1	as	as	SCONJ
can-224	142	2	the	the	DET
can-224	142	3	exonuclease	exonuclease	NOUN
can-224	142	4	and	and	CCONJ
can-224	142	5	endonuclease	endonuclease	NOUN
can-224	142	6	of	of	ADP
can-224	142	7	the	the	DET
can-224	142	8	in	in	ADJ
can-224	142	9	vivo	vivo	NOUN
can-224	142	10	are	be	AUX
can-224	142	11	ubiquitous	ubiquitous	ADJ
can-224	142	12	and	and	CCONJ
can-224	142	13	degrading	degrading	ADJ
can-224	142	14	,	,	PUNCT
can-224	142	15	jianping	jianpe	VERB
can-224	142	16	wu	wu	PROPN
can-224	142	17	,	,	PUNCT
can-224	142	18	et	et	PROPN
can-224	142	19	al	al	PROPN
can-224	142	20	17	17	NUM
can-224	142	21	the	the	DET
can-224	142	22	bioavailability	bioavailability	NOUN
can-224	142	23	of	of	ADP
can-224	142	24	oligonucleotides	oligonucleotide	NOUN
can-224	142	25	is	be	AUX
can-224	142	26	reduced	reduce	VERB
can-224	142	27	.	.	PUNCT
can-224	143	1	the	the	DET
can-224	143	2	use	use	NOUN
can-224	143	3	of	of	ADP
can-224	143	4	nanotechnology	nanotechnology	NOUN
can-224	143	5	gene	gene	NOUN
can-224	143	6	transfer	transfer	NOUN
can-224	143	7	can	can	AUX
can-224	143	8	overcome	overcome	VERB
can-224	143	9	this	this	DET
can-224	143	10	shortcoming	shortcoming	NOUN
can-224	143	11	;	;	PUNCT
can-224	143	12	nano	nano	NOUN
can-224	143	13	-	-	PUNCT
can-224	143	14	drugs	drug	NOUN
can-224	143	15	have	have	VERB
can-224	143	16	more	more	ADJ
can-224	143	17	than	than	ADP
can-224	143	18	other	other	ADJ
can-224	143	19	carriers	carrier	NOUN
can-224	143	20	do	do	AUX
can-224	143	21	not	not	PART
can-224	143	22	have	have	VERB
can-224	143	23	many	many	ADJ
can-224	143	24	advantages	advantage	NOUN
can-224	143	25	in	in	ADP
can-224	143	26	clinical	clinical	ADJ
can-224	143	27	applications	application	NOUN
can-224	143	28	has	have	VERB
can-224	143	29	a	a	DET
can-224	143	30	very	very	ADV
can-224	143	31	good	good	ADJ
can-224	143	32	prospect	prospect	NOUN
can-224	143	33	.	.	PUNCT
can-224	144	1	4.2	4.2	NUM
can-224	144	2	.	.	PUNCT
can-224	144	3	application	application	NOUN
can-224	144	4	of	of	ADP
can-224	144	5	nano	nano	NOUN
can-224	144	6	-	-	PUNCT
can-224	144	7	drug	drug	NOUN
can-224	144	8	carrier	carrier	NOUN
can-224	144	9	in	in	ADP
can-224	144	10	pharmaceutical	pharmaceutical	ADJ
can-224	144	11	the	the	DET
can-224	144	12	drug	drug	NOUN
can-224	144	13	-	-	PUNCT
can-224	144	14	loaded	load	VERB
can-224	144	15	nanoparticles	nanoparticle	NOUN
can-224	144	16	are	be	AUX
can-224	144	17	nanotechnology	nanotechnology	NOUN
can-224	144	18	combined	combine	VERB
can-224	144	19	with	with	ADP
can-224	144	20	modern	modern	ADJ
can-224	144	21	medical	medical	ADJ
can-224	144	22	products	product	NOUN
can-224	144	23	and	and	CCONJ
can-224	144	24	are	be	AUX
can-224	144	25	a	a	DET
can-224	144	26	super	super	ADJ
can-224	144	27	-	-	ADJ
can-224	144	28	ball	ball	NOUN
can-224	144	29	drug	drug	NOUN
can-224	144	30	carrier	carrier	NOUN
can-224	144	31	.	.	PUNCT
can-224	145	1	in	in	ADP
can-224	145	2	recent	recent	ADJ
can-224	145	3	years	year	NOUN
can-224	145	4	,	,	PUNCT
can-224	145	5	it	it	PRON
can-224	145	6	is	be	AUX
can-224	145	7	a	a	DET
can-224	145	8	new	new	ADJ
can-224	145	9	drug	drug	NOUN
can-224	145	10	delivery	delivery	NOUN
can-224	145	11	and	and	CCONJ
can-224	145	12	sustained	sustained	ADJ
can-224	145	13	release	release	NOUN
can-224	145	14	dosage	dosage	NOUN
can-224	145	15	form	form	NOUN
can-224	145	16	,	,	PUNCT
can-224	145	17	including	include	VERB
can-224	145	18	nanoparticles	nanoparticle	NOUN
can-224	145	19	and	and	CCONJ
can-224	145	20	nano	nano	NOUN
can-224	145	21	capsules	capsule	NOUN
can-224	145	22	.	.	PUNCT
can-224	146	1	its	its	PRON
can-224	146	2	advantage	advantage	NOUN
can-224	146	3	is	be	AUX
can-224	146	4	smaller	small	ADJ
can-224	146	5	than	than	ADP
can-224	146	6	the	the	DET
can-224	146	7	cells	cell	NOUN
can-224	146	8	(	(	PUNCT
can-224	146	9	10	10	NUM
can-224	146	10	-	-	PUNCT
can-224	146	11	loonm	loonm	NOUN
can-224	146	12	)	)	PUNCT
can-224	146	13	,	,	PUNCT
can-224	146	14	so	so	SCONJ
can-224	146	15	it	it	PRON
can-224	146	16	can	can	AUX
can-224	146	17	be	be	AUX
can-224	146	18	absorbed	absorb	VERB
can-224	146	19	through	through	ADP
can-224	146	20	the	the	DET
can-224	146	21	organization	organization	NOUN
can-224	146	22	and	and	CCONJ
can-224	146	23	cells	cell	NOUN
can-224	146	24	,	,	PUNCT
can-224	146	25	after	after	SCONJ
can-224	146	26	special	special	ADJ
can-224	146	27	treatment	treatment	NOUN
can-224	146	28	can	can	AUX
can-224	146	29	be	be	AUX
can-224	146	30	guided	guide	VERB
can-224	146	31	to	to	ADP
can-224	146	32	the	the	DET
can-224	146	33	organization	organization	NOUN
can-224	146	34	and	and	CCONJ
can-224	146	35	management	management	NOUN
can-224	146	36	of	of	ADP
can-224	146	37	the	the	DET
can-224	146	38	organ	organ	NOUN
can-224	146	39	.	.	PUNCT
can-224	147	1	controlled	control	VERB
can-224	147	2	release	release	NOUN
can-224	147	3	of	of	ADP
can-224	147	4	drug	drug	NOUN
can-224	147	5	particles	particle	NOUN
can-224	147	6	:	:	PUNCT
can-224	147	7	with	with	ADP
can-224	147	8	the	the	DET
can-224	147	9	previous	previous	ADJ
can-224	147	10	control	control	NOUN
can-224	147	11	of	of	ADP
can-224	147	12	the	the	DET
can-224	147	13	preparation	preparation	NOUN
can-224	147	14	of	of	ADP
can-224	147	15	different	different	ADJ
can-224	147	16	formulations	formulation	NOUN
can-224	147	17	,	,	PUNCT
can-224	147	18	the	the	DET
can-224	147	19	release	release	NOUN
can-224	147	20	of	of	ADP
can-224	147	21	drug	drug	NOUN
can-224	147	22	-	-	PUNCT
can-224	147	23	loaded	load	VERB
can-224	147	24	nanoparticles	nanoparticle	NOUN
can-224	147	25	has	have	VERB
can-224	147	26	a	a	DET
can-224	147	27	specifi	specifi	PROPN
can-224	147	28	c	c	PROPN
can-224	147	29	law	law	NOUN
can-224	147	30	of	of	ADP
can-224	147	31	the	the	DET
can-224	147	32	process	process	NOUN
can-224	147	33	,	,	PUNCT
can-224	147	34	due	due	ADP
can-224	147	35	to	to	ADP
can-224	147	36	the	the	DET
can-224	147	37	dissolution	dissolution	NOUN
can-224	147	38	of	of	ADP
can-224	147	39	the	the	DET
can-224	147	40	wall	wall	NOUN
can-224	147	41	and	and	CCONJ
can-224	147	42	the	the	DET
can-224	147	43	role	role	NOUN
can-224	147	44	of	of	ADP
can-224	147	45	enzyme	enzyme	NOUN
can-224	147	46	micro	micro	NOUN
can-224	147	47	-	-	NOUN
can-224	147	48	organisms	organism	NOUN
can-224	147	49	,	,	PUNCT
can-224	147	50	drugs	drug	NOUN
can-224	147	51	can	can	AUX
can-224	147	52	make	make	VERB
can-224	147	53	nanoparticles	nanoparticle	NOUN
can-224	147	54	in	in	ADP
can-224	147	55	the	the	DET
can-224	147	56	local	local	ADJ
can-224	147	57	stay	stay	NOUN
can-224	147	58	and	and	CCONJ
can-224	147	59	to	to	PART
can-224	147	60	achieve	achieve	VERB
can-224	147	61	eff	eff	PROPN
can-224	147	62	ective	ective	ADJ
can-224	147	63	concentration	concentration	NOUN
can-224	147	64	,	,	PUNCT
can-224	147	65	without	without	ADP
can-224	147	66	causing	cause	VERB
can-224	147	67	systemic	systemic	ADJ
can-224	147	68	toxicity	toxicity	NOUN
can-224	147	69	.	.	PUNCT
can-224	148	1	for	for	ADP
can-224	148	2	some	some	PRON
can-224	148	3	of	of	ADP
can-224	148	4	the	the	DET
can-224	148	5	immune	immune	ADJ
can-224	148	6	system	system	NOUN
can-224	148	7	and	and	CCONJ
can-224	148	8	the	the	DET
can-224	148	9	central	central	ADJ
can-224	148	10	nervous	nervous	ADJ
can-224	148	11	system	system	NOUN
can-224	148	12	drugs	drug	NOUN
can-224	148	13	,	,	PUNCT
can-224	148	14	the	the	DET
can-224	148	15	disease	disease	NOUN
can-224	148	16	of	of	ADP
can-224	148	17	the	the	DET
can-224	148	18	treatment	treatment	NOUN
can-224	148	19	of	of	ADP
can-224	148	20	chronic	chronic	ADJ
can-224	148	21	diseases	disease	NOUN
can-224	148	22	,	,	PUNCT
can-224	148	23	long	long	ADJ
can-224	148	24	-	-	PUNCT
can-224	148	25	term	term	NOUN
can-224	148	26	medication	medication	NOUN
can-224	148	27	.	.	PUNCT
can-224	149	1	drug	drug	NOUN
can-224	149	2	-	-	PUNCT
can-224	149	3	loaded	load	VERB
can-224	149	4	nanoparticles	nanoparticle	NOUN
can-224	149	5	as	as	ADP
can-224	149	6	a	a	DET
can-224	149	7	new	new	ADJ
can-224	149	8	type	type	NOUN
can-224	149	9	of	of	ADP
can-224	149	10	drug	drug	NOUN
can-224	149	11	-	-	PUNCT
can-224	149	12	controlled	control	VERB
can-224	149	13	release	release	NOUN
can-224	149	14	formulations	formulation	NOUN
can-224	149	15	,	,	PUNCT
can-224	149	16	especially	especially	ADV
can-224	149	17	for	for	ADP
can-224	149	18	these	these	DET
can-224	149	19	drugs	drug	NOUN
can-224	149	20	.	.	PUNCT
can-224	150	1	it	it	PRON
can-224	150	2	was	be	AUX
can-224	150	3	found	find	VERB
can-224	150	4	that	that	SCONJ
can-224	150	5	rats	rat	NOUN
can-224	150	6	were	be	AUX
can-224	150	7	subcutaneously	subcutaneously	ADV
can-224	150	8	injected	inject	VERB
can-224	150	9	with	with	ADP
can-224	150	10	insulin	insulin	NOUN
can-224	150	11	nanoparticles	nanoparticle	NOUN
can-224	150	12	.	.	PUNCT
can-224	151	1	the	the	DET
can-224	151	2	hypoglycemic	hypoglycemic	PROPN
can-224	151	3	eff	eff	PROPN
can-224	151	4	ect	ect	VERB
can-224	151	5	could	could	AUX
can-224	151	6	last	last	VERB
can-224	151	7	for	for	ADP
can-224	151	8	three	three	NUM
can-224	151	9	days	day	NOUN
can-224	151	10	and	and	CCONJ
can-224	151	11	had	have	VERB
can-224	151	12	a	a	DET
can-224	151	13	signifi	signifi	NOUN
can-224	151	14	ca	can	AUX
can-224	151	15	nt	not	PART
can-224	151	16	reaction	reaction	VERB
can-224	151	17	with	with	ADP
can-224	151	18	the	the	DET
can-224	151	19	absorption	absorption	NOUN
can-224	151	20	of	of	ADP
can-224	151	21	the	the	DET
can-224	151	22	drug	drug	NOUN
can-224	151	23	.	.	PUNCT
can-224	152	1	it	it	PRON
can-224	152	2	was	be	AUX
can-224	152	3	also	also	ADV
can-224	152	4	found	find	VERB
can-224	152	5	that	that	SCONJ
can-224	152	6	the	the	DET
can-224	152	7	hypoglycemic	hypoglycemic	PROPN
can-224	152	8	eff	eff	PROPN
can-224	152	9	ect	ect	ADP
can-224	152	10	of	of	ADP
can-224	152	11	insulin	insulin	NOUN
can-224	152	12	nanoparticles	nanoparticle	NOUN
can-224	152	13	was	be	AUX
can-224	152	14	almost	almost	ADV
can-224	152	15	three	three	NUM
can-224	152	16	times	time	NOUN
can-224	152	17	a	a	DET
can-224	152	18	day	day	NOUN
can-224	152	19	with	with	ADP
can-224	152	20	conventional	conventional	ADJ
can-224	152	21	insulin	insulin	NOUN
can-224	152	22	therapy	therapy	NOUN
can-224	152	23	have	have	VERB
can-224	152	24	the	the	DET
can-224	152	25	same	same	ADJ
can-224	152	26	eff	eff	PROPN
can-224	152	27	ect	ect	NOUN
can-224	152	28	,	,	PUNCT
can-224	152	29	thus	thus	ADV
can-224	152	30	proving	prove	VERB
can-224	152	31	that	that	SCONJ
can-224	152	32	insulin	insulin	NOUN
can-224	152	33	can	can	AUX
can-224	152	34	be	be	AUX
can-224	152	35	made	make	VERB
can-224	152	36	under	under	ADP
can-224	152	37	the	the	DET
can-224	152	38	nano	nano	NOUN
can-224	152	39	-	-	PUNCT
can-224	152	40	carrier	carrier	NOUN
can-224	152	41	particles	particle	NOUN
can-224	152	42	can	can	AUX
can-224	152	43	prolong	prolong	VERB
can-224	152	44	the	the	DET
can-224	152	45	role	role	NOUN
can-224	152	46	of	of	ADP
can-224	152	47	time	time	NOUN
can-224	152	48	and	and	CCONJ
can-224	152	49	lower	low	ADJ
can-224	152	50	blood	blood	NOUN
can-224	152	51	sugar	sugar	NOUN
can-224	152	52	,	,	PUNCT
can-224	152	53	more	more	ADJ
can-224	152	54	eff	eff	PROPN
can-224	152	55	ective	ective	ADJ
can-224	152	56	than	than	ADP
can-224	152	57	the	the	DET
can-224	152	58	same	same	ADJ
can-224	152	59	dose	dose	NOUN
can-224	152	60	of	of	ADP
can-224	152	61	insulin	insulin	NOUN
can-224	152	62	.	.	PUNCT
can-224	153	1	drug	drug	NOUN
can-224	153	2	-	-	PUNCT
can-224	153	3	loaded	load	VERB
can-224	153	4	nano	nano	NOUN
can-224	153	5	-	-	PUNCT
can-224	153	6	enhancing	enhance	VERB
can-224	153	7	drug	drug	NOUN
can-224	153	8	targeting	target	VERB
can-224	153	9	eff	eff	PROPN
can-224	153	10	ect	ect	NOUN
can-224	153	11	:	:	PUNCT
can-224	153	12	such	such	ADJ
can-224	153	13	micro	micro	ADJ
can-224	153	14	particles	particle	NOUN
can-224	153	15	are	be	AUX
can-224	153	16	prepared	prepare	VERB
can-224	153	17	by	by	ADP
can-224	153	18	the	the	DET
can-224	153	19	use	use	NOUN
can-224	153	20	of	of	ADP
can-224	153	21	various	various	ADJ
can-224	153	22	human	human	ADJ
can-224	153	23	tissues	tissue	NOUN
can-224	153	24	or	or	CCONJ
can-224	153	25	vectors	vector	NOUN
can-224	153	26	of	of	ADP
can-224	153	27	diff	diff	NOUN
can-224	153	28	erent	erent	NOUN
can-224	153	29	affi	affi	PROPN
can-224	153	30	nity	nity	NOUN
can-224	153	31	for	for	ADP
can-224	153	32	the	the	DET
can-224	153	33	preparation	preparation	NOUN
can-224	153	34	of	of	ADP
can-224	153	35	drug	drug	NOUN
can-224	153	36	-	-	PUNCT
can-224	153	37	loaded	load	VERB
can-224	153	38	micro	micro	ADJ
can-224	153	39	particles	particle	NOUN
can-224	153	40	according	accord	VERB
can-224	153	41	to	to	ADP
can-224	153	42	clinical	clinical	ADJ
can-224	153	43	needs	need	NOUN
can-224	153	44	,	,	PUNCT
can-224	153	45	or	or	CCONJ
can-224	153	46	the	the	DET
can-224	153	47	monoclonal	monoclonal	NOUN
can-224	153	48	antibodies	antibody	NOUN
can-224	153	49	are	be	AUX
can-224	153	50	bound	bind	VERB
can-224	153	51	to	to	ADP
can-224	153	52	the	the	DET
can-224	153	53	vector	vector	NOUN
can-224	153	54	,	,	PUNCT
can-224	153	55	the	the	DET
can-224	153	56	drug	drug	NOUN
can-224	153	57	can	can	AUX
can-224	153	58	be	be	AUX
can-224	153	59	highly	highly	ADV
can-224	153	60	selective	selective	ADJ
can-224	153	61	the	the	DET
can-224	153	62	dispersion	dispersion	NOUN
can-224	153	63	in	in	ADP
can-224	153	64	the	the	DET
can-224	153	65	role	role	NOUN
can-224	153	66	of	of	ADP
can-224	153	67	the	the	DET
can-224	153	68	object	object	NOUN
can-224	153	69	,	,	PUNCT
can-224	153	70	thereby	thereby	ADV
can-224	153	71	enhancing	enhance	VERB
can-224	153	72	effi	effi	PROPN
can-224	153	73	cacy	cacy	NOUN
can-224	153	74	and	and	CCONJ
can-224	153	75	reduce	reduce	VERB
can-224	153	76	side	side	NOUN
can-224	153	77	eff	eff	PROPN
can-224	153	78	ects	ect	VERB
can-224	153	79	.	.	PUNCT
can-224	154	1	from	from	ADP
can-224	154	2	target	target	NOUN
can-224	154	3	organs	organ	NOUN
can-224	154	4	,	,	PUNCT
can-224	154	5	target	target	NOUN
can-224	154	6	cells	cell	NOUN
can-224	154	7	to	to	ADP
can-224	154	8	the	the	DET
can-224	154	9	most	most	ADV
can-224	154	10	advanced	advanced	ADJ
can-224	154	11	intracellular	intracellular	ADJ
can-224	154	12	target	target	NOUN
can-224	154	13	mechanisms	mechanism	NOUN
can-224	154	14	,	,	PUNCT
can-224	154	15	these	these	DET
can-224	154	16	three	three	NUM
can-224	154	17	targeted	target	VERB
can-224	154	18	therapy	therapy	NOUN
can-224	154	19	can	can	AUX
can-224	154	20	be	be	AUX
can-224	154	21	done	do	VERB
can-224	154	22	through	through	ADP
can-224	154	23	drug	drug	NOUN
can-224	154	24	nanoparticles	nanoparticle	NOUN
can-224	154	25	.	.	PUNCT
can-224	155	1	when	when	SCONJ
can-224	155	2	the	the	DET
can-224	155	3	drugloaded	drugloade	VERB
can-224	155	4	nanoparticles	nanoparticle	NOUN
can-224	155	5	and	and	CCONJ
can-224	155	6	the	the	DET
can-224	155	7	drug	drug	NOUN
can-224	155	8	form	form	NOUN
can-224	155	9	a	a	DET
can-224	155	10	complex	complex	NOUN
can-224	155	11	,	,	PUNCT
can-224	155	12	depending	depend	VERB
can-224	155	13	on	on	ADP
can-224	155	14	the	the	DET
can-224	155	15	purpose	purpose	NOUN
can-224	155	16	of	of	ADP
can-224	155	17	the	the	DET
can-224	155	18	treatment	treatment	NOUN
can-224	155	19	,	,	PUNCT
can-224	155	20	the	the	DET
can-224	155	21	choice	choice	NOUN
can-224	155	22	of	of	ADP
can-224	155	23	blood	blood	NOUN
can-224	155	24	through	through	ADP
can-224	155	25	the	the	DET
can-224	155	26	circulation	circulation	NOUN
can-224	155	27	or	or	CCONJ
can-224	155	28	diff	diff	NOUN
can-224	155	29	erent	erent	NOUN
can-224	155	30	ways	way	NOUN
can-224	155	31	to	to	PART
can-224	155	32	selectively	selectively	ADV
can-224	155	33	enter	enter	VERB
can-224	155	34	the	the	DET
can-224	155	35	body	body	NOUN
can-224	155	36	's	's	PART
can-224	155	37	specifi	specifi	PROPN
can-224	155	38	c	c	PROPN
can-224	155	39	tissue	tissue	NOUN
can-224	155	40	and	and	CCONJ
can-224	155	41	cells	cell	NOUN
can-224	155	42	to	to	PART
can-224	155	43	achieve	achieve	VERB
can-224	155	44	treatment	treatment	NOUN
can-224	155	45	.	.	PUNCT
can-224	156	1	characteristics	characteristic	NOUN
can-224	156	2	of	of	ADP
can-224	156	3	nanoparticles	nanoparticle	NOUN
can-224	156	4	into	into	ADP
can-224	156	5	the	the	DET
can-224	156	6	cell	cell	NOUN
can-224	156	7	structure	structure	NOUN
can-224	156	8	and	and	CCONJ
can-224	156	9	to	to	PART
can-224	156	10	achieve	achieve	VERB
can-224	156	11	gene	gene	NOUN
can-224	156	12	therapy	therapy	NOUN
can-224	156	13	.	.	PUNCT
can-224	157	1	now	now	ADV
can-224	157	2	the	the	DET
can-224	157	3	study	study	NOUN
can-224	157	4	of	of	ADP
can-224	157	5	more	more	ADJ
can-224	157	6	objects	object	NOUN
can-224	157	7	with	with	ADP
can-224	157	8	liver	liver	NOUN
can-224	157	9	,	,	PUNCT
can-224	157	10	blood	blood	NOUN
can-224	157	11	system	system	NOUN
can-224	157	12	,	,	PUNCT
can-224	157	13	gastrointestinal	gastrointestinal	ADJ
can-224	157	14	tract	tract	NOUN
can-224	157	15	,	,	PUNCT
can-224	157	16	lung	lung	NOUN
can-224	157	17	,	,	PUNCT
can-224	157	18	etc	etc	X
can-224	157	19	.	.	X
can-224	157	20	in	in	ADP
can-224	157	21	the	the	DET
can-224	157	22	liver	liver	NOUN
can-224	157	23	,	,	PUNCT
can-224	157	24	etc	etc	X
can-224	157	25	.	.	X
can-224	157	26	,	,	PUNCT
can-224	157	27	for	for	ADP
can-224	157	28	example	example	NOUN
can-224	157	29	,	,	PUNCT
can-224	157	30	drug	drug	NOUN
can-224	157	31	nanoparticle	nanoparticle	NOUN
can-224	157	32	composite	composite	ADJ
can-224	157	33	material	material	NOUN
can-224	157	34	in	in	ADP
can-224	157	35	two	two	NUM
can-224	157	36	ways	way	NOUN
can-224	157	37	to	to	PART
can-224	157	38	achieve	achieve	VERB
can-224	157	39	positioning	positioning	NOUN
can-224	157	40	:	:	PUNCT
can-224	157	41	the	the	DET
can-224	157	42	complex	complex	NOUN
can-224	157	43	is	be	AUX
can-224	157	44	kuepfer	kuepfer	NOUN
can-224	157	45	cell	cell	NOUN
can-224	157	46	phagocytosis	phagocytosis	NOUN
can-224	157	47	,	,	PUNCT
can-224	157	48	in	in	ADP
can-224	157	49	the	the	DET
can-224	157	50	liver	liver	NOUN
can-224	157	51	drug	drug	NOUN
can-224	157	52	accumulation	accumulation	NOUN
can-224	157	53	,	,	PUNCT
can-224	157	54	and	and	CCONJ
can-224	157	55	then	then	ADV
can-224	157	56	gradually	gradually	ADV
can-224	157	57	fall	fall	VERB
can-224	157	58	into	into	ADP
can-224	157	59	the	the	DET
can-224	157	60	blood	blood	NOUN
can-224	157	61	circulation	circulation	NOUN
can-224	157	62	,	,	PUNCT
can-224	157	63	so	so	SCONJ
can-224	157	64	that	that	SCONJ
can-224	157	65	the	the	DET
can-224	157	66	increase	increase	NOUN
can-224	157	67	in	in	ADP
can-224	157	68	liver	liver	NOUN
can-224	157	69	drug	drug	NOUN
can-224	157	70	concentration	concentration	NOUN
can-224	157	71	,	,	PUNCT
can-224	157	72	reduce	reduce	VERB
can-224	157	73	other	other	ADJ
can-224	157	74	organs	organ	NOUN
can-224	157	75	side	side	NOUN
can-224	157	76	eff	eff	PROPN
can-224	157	77	ects	ect	NOUN
can-224	157	78	,	,	PUNCT
can-224	157	79	known	know	VERB
can-224	157	80	as	as	ADP
can-224	157	81	passive	passive	ADJ
can-224	157	82	targeting	targeting	NOUN
can-224	157	83	side	side	NOUN
can-224	157	84	eff	eff	PROPN
can-224	157	85	ects	ect	VERB
can-224	157	86	;	;	PUNCT
can-224	157	87	when	when	SCONJ
can-224	157	88	the	the	DET
can-224	157	89	nanoparticles	nanoparticle	NOUN
can-224	157	90	are	be	AUX
can-224	157	91	small	small	ADJ
can-224	157	92	enough	enough	ADV
can-224	157	93	(	(	PUNCT
can-224	157	94	100	100	NUM
can-224	157	95	-	-	SYM
can-224	157	96	150	150	NUM
can-224	157	97	nm	nm	NOUN
can-224	157	98	)	)	PUNCT
can-224	157	99	,	,	PUNCT
can-224	157	100	and	and	CCONJ
can-224	157	101	covered	cover	VERB
can-224	157	102	with	with	ADP
can-224	157	103	a	a	DET
can-224	157	104	special	special	ADJ
can-224	157	105	coating	coating	NOUN
can-224	157	106	layer	layer	NOUN
can-224	157	107	surface	surface	NOUN
can-224	157	108	,	,	PUNCT
can-224	157	109	kuepfer	kuepfer	NOUN
can-224	157	110	cells	cell	NOUN
can-224	157	111	can	can	AUX
can-224	157	112	escape	escape	VERB
can-224	157	113	phagocytic	phagocytic	ADJ
can-224	157	114	cells	cell	NOUN
can-224	157	115	,	,	PUNCT
can-224	157	116	connect	connect	VERB
can-224	157	117	monoclonal	monoclonal	NOUN
can-224	157	118	antibodies	antibody	NOUN
can-224	157	119	and	and	CCONJ
can-224	157	120	other	other	ADJ
can-224	157	121	positioning	positioning	NOUN
can-224	157	122	in	in	ADP
can-224	157	123	the	the	DET
can-224	157	124	role	role	NOUN
can-224	157	125	of	of	ADP
can-224	157	126	liver	liver	ADJ
can-224	157	127	parenchymal	parenchymal	ADJ
can-224	157	128	cells	cell	NOUN
can-224	157	129	,	,	PUNCT
can-224	157	130	known	know	VERB
can-224	157	131	as	as	ADP
can-224	157	132	active	active	ADJ
can-224	157	133	targeting	target	VERB
can-224	157	134	[	[	X
can-224	157	135	22	22	NUM
can-224	157	136	]	]	PUNCT
can-224	157	137	.	.	PUNCT
can-224	158	1	regardless	regardless	ADV
can-224	158	2	of	of	ADP
can-224	158	3	the	the	DET
can-224	158	4	approach	approach	NOUN
can-224	158	5	taken	take	VERB
can-224	158	6	,	,	PUNCT
can-224	158	7	the	the	DET
can-224	158	8	size	size	NOUN
can-224	158	9	and	and	CCONJ
can-224	158	10	shape	shape	NOUN
can-224	158	11	of	of	ADP
can-224	158	12	the	the	DET
can-224	158	13	particles	particle	NOUN
can-224	158	14	is	be	AUX
can-224	158	15	critical	critical	ADJ
can-224	158	16	to	to	ADP
can-224	158	17	achieving	achieve	VERB
can-224	158	18	targeting	target	VERB
can-224	158	19	in	in	ADP
can-224	158	20	order	order	NOUN
can-224	158	21	to	to	PART
can-224	158	22	achieve	achieve	VERB
can-224	158	23	localization	localization	NOUN
can-224	158	24	while	while	SCONJ
can-224	158	25	the	the	DET
can-224	158	26	specifi	specifi	PROPN
can-224	158	27	city	city	PROPN
can-224	158	28	of	of	ADP
can-224	158	29	the	the	DET
can-224	158	30	antibody	antibody	NOUN
can-224	158	31	on	on	ADP
can-224	158	32	the	the	DET
can-224	158	33	cell	cell	NOUN
can-224	158	34	surface	surface	NOUN
can-224	158	35	can	can	AUX
can-224	158	36	improve	improve	VERB
can-224	158	37	the	the	DET
can-224	158	38	selectivity	selectivity	NOUN
can-224	158	39	.	.	PUNCT
can-224	159	1	manufacturing	manufacture	VERB
can-224	159	2	nano	nano	NOUN
can-224	159	3	-	-	PUNCT
can-224	159	4	robots	robot	NOUN
can-224	159	5	to	to	PART
can-224	159	6	replace	replace	VERB
can-224	159	7	traditional	traditional	ADJ
can-224	159	8	drugs	drug	NOUN
can-224	159	9	:	:	PUNCT
can-224	159	10	nano	nano	NOUN
can-224	159	11	-	-	PUNCT
can-224	159	12	robot	robot	NOUN
can-224	159	13	,	,	PUNCT
can-224	159	14	also	also	ADV
can-224	159	15	known	know	VERB
can-224	159	16	as	as	ADP
can-224	159	17	molecular	molecular	ADJ
can-224	159	18	robots	robot	NOUN
can-224	159	19	,	,	PUNCT
can-224	159	20	is	be	AUX
can-224	159	21	a	a	DET
can-224	159	22	combination	combination	NOUN
can-224	159	23	of	of	ADP
can-224	159	24	nano	nano	NOUN
can-224	159	25	-	-	PUNCT
can-224	159	26	mechanical	mechanical	ADJ
can-224	159	27	devices	device	NOUN
can-224	159	28	and	and	CCONJ
can-224	159	29	biological	biological	ADJ
can-224	159	30	systems	system	NOUN
can-224	159	31	(	(	PUNCT
can-224	159	32	such	such	ADJ
can-224	159	33	as	as	ADP
can-224	159	34	enzyme	enzyme	NOUN
can-224	159	35	and	and	CCONJ
can-224	159	36	nano	nano	NOUN
can-224	159	37	-	-	PUNCT
can-224	159	38	gear	gear	NOUN
can-224	159	39	combination	combination	NOUN
can-224	159	40	)	)	PUNCT
can-224	159	41	.	.	PUNCT
can-224	160	1	nano	nano	NOUN
can-224	160	2	-	-	PUNCT
can-224	160	3	robot	robot	NOUN
can-224	160	4	with	with	ADP
can-224	160	5	its	its	PRON
can-224	160	6	unique	unique	ADJ
can-224	160	7	structure	structure	NOUN
can-224	160	8	and	and	CCONJ
can-224	160	9	nature	nature	NOUN
can-224	160	10	,	,	PUNCT
can-224	160	11	so	so	SCONJ
can-224	160	12	that	that	SCONJ
can-224	160	13	in	in	ADP
can-224	160	14	many	many	ADJ
can-224	160	15	areas	area	NOUN
can-224	160	16	have	have	AUX
can-224	160	17	shown	show	VERB
can-224	160	18	extraordinary	extraordinary	ADJ
can-224	160	19	vitality	vitality	NOUN
can-224	160	20	,	,	PUNCT
can-224	160	21	to	to	PART
can-224	160	22	solve	solve	VERB
can-224	160	23	the	the	DET
can-224	160	24	traditional	traditional	ADJ
can-224	160	25	drug	drug	NOUN
can-224	160	26	mouth	mouth	NOUN
can-224	160	27	problems	problem	NOUN
can-224	160	28	[	[	X
can-224	160	29	23	23	NUM
can-224	160	30	]	]	PUNCT
can-224	160	31	.	.	PUNCT
can-224	161	1	in	in	ADP
can-224	161	2	the	the	DET
can-224	161	3	fi	fi	NOUN
can-224	161	4	eld	eld	NOUN
can-224	161	5	of	of	ADP
can-224	161	6	cardiovascular	cardiovascular	ADJ
can-224	161	7	,	,	PUNCT
can-224	161	8	nano	nano	NOUN
can-224	161	9	-	-	PUNCT
can-224	161	10	robot	robot	NOUN
can-224	161	11	can	can	AUX
can-224	161	12	be	be	AUX
can-224	161	13	injected	inject	VERB
can-224	161	14	into	into	ADP
can-224	161	15	the	the	DET
can-224	161	16	body	body	NOUN
can-224	161	17	,	,	PUNCT
can-224	161	18	a	a	DET
can-224	161	19	blood	blood	NOUN
can-224	161	20	vessel	vessel	NOUN
can-224	161	21	operation	operation	NOUN
can-224	161	22	of	of	ADP
can-224	161	23	the	the	DET
can-224	161	24	robot	robot	NOUN
can-224	161	25	.	.	PUNCT
can-224	162	1	these	these	DET
can-224	162	2	molecular	molecular	ADJ
can-224	162	3	robots	robot	NOUN
can-224	162	4	capture	capture	VERB
can-224	162	5	energy	energy	NOUN
can-224	162	6	in	in	ADP
can-224	162	7	blood	blood	NOUN
can-224	162	8	glucose	glucose	NOUN
can-224	162	9	and	and	CCONJ
can-224	162	10	oxygen	oxygen	NOUN
can-224	162	11	to	to	PART
can-224	162	12	remove	remove	VERB
can-224	162	13	blood	blood	NOUN
can-224	162	14	vessel	vessel	NOUN
can-224	162	15	thrombosis	thrombosis	NOUN
can-224	162	16	,	,	PUNCT
can-224	162	17	remove	remove	VERB
can-224	162	18	heart	heart	NOUN
can-224	162	19	and	and	CCONJ
can-224	162	20	internal	internal	ADJ
can-224	162	21	arterial	arterial	ADJ
can-224	162	22	lipid	lipid	NOUN
can-224	162	23	deposits	deposit	NOUN
can-224	162	24	;	;	PUNCT
can-224	162	25	in	in	ADP
can-224	162	26	genetic	genetic	ADJ
can-224	162	27	engineering	engineering	NOUN
can-224	162	28	,	,	PUNCT
can-224	162	29	gene	gene	NOUN
can-224	162	30	assembly	assembly	NOUN
can-224	162	31	can	can	AUX
can-224	162	32	be	be	AUX
can-224	162	33	performed	perform	VERB
can-224	162	34	by	by	ADP
can-224	162	35	nano	nano	NOUN
can-224	162	36	robots	robot	NOUN
can-224	162	37	,	,	PUNCT
can-224	162	38	that	that	ADV
can-224	162	39	is	is	ADV
can-224	162	40	,	,	PUNCT
can-224	162	41	the	the	DET
can-224	162	42	gene	gene	NOUN
can-224	162	43	can	can	AUX
can-224	162	44	be	be	AUX
can-224	162	45	removed	remove	VERB
can-224	162	46	or	or	CCONJ
can-224	162	47	harmful	harmful	ADJ
can-224	162	48	dna	dna	NOUN
can-224	162	49	,	,	PUNCT
can-224	162	50	or	or	CCONJ
can-224	162	51	in	in	ADP
can-224	162	52	the	the	DET
can-224	162	53	normal	normal	ADJ
can-224	162	54	dna	dna	PROPN
can-224	162	55	assembly	assembly	NOUN
can-224	162	56	into	into	ADP
can-224	162	57	the	the	DET
can-224	162	58	chromosome	chromosome	NOUN
can-224	162	59	,	,	PUNCT
can-224	162	60	so	so	SCONJ
can-224	162	61	that	that	SCONJ
can-224	162	62	the	the	DET
can-224	162	63	normal	normal	ADJ
can-224	162	64	operation	operation	NOUN
can-224	162	65	of	of	ADP
can-224	162	66	the	the	DET
can-224	162	67	human	human	ADJ
can-224	162	68	body	body	NOUN
can-224	162	69	;	;	PUNCT
can-224	162	70	nano	nano	NOUN
can-224	162	71	-	-	PUNCT
can-224	162	72	robot	robot	NOUN
can-224	162	73	can	can	AUX
can-224	162	74	be	be	AUX
can-224	162	75	used	use	VERB
can-224	162	76	for	for	ADP
can-224	162	77	organ	organ	NOUN
can-224	162	78	repair	repair	NOUN
can-224	162	79	,	,	PUNCT
can-224	162	80	such	such	ADJ
can-224	162	81	as	as	ADP
can-224	162	82	repair	repair	NOUN
can-224	162	83	damaged	damage	VERB
can-224	162	84	tissue	tissue	NOUN
can-224	162	85	and	and	CCONJ
can-224	162	86	organs	organ	NOUN
can-224	162	87	,	,	PUNCT
can-224	162	88	complete	complete	ADJ
can-224	162	89	cosmetic	cosmetic	ADJ
can-224	162	90	surgery	surgery	NOUN
can-224	162	91	;	;	PUNCT
can-224	162	92	in	in	ADP
can-224	162	93	addition	addition	NOUN
can-224	162	94	,	,	PUNCT
can-224	162	95	nano	nano	NOUN
can-224	162	96	-	-	PUNCT
can-224	162	97	robot	robot	NOUN
can-224	162	98	also	also	ADV
can-224	162	99	swallowed	swallow	VERB
can-224	162	100	bacteria	bacteria	NOUN
can-224	162	101	and	and	CCONJ
can-224	162	102	kill	kill	VERB
can-224	162	103	cancer	cancer	NOUN
can-224	162	104	cells	cell	NOUN
can-224	162	105	in	in	ADP
can-224	162	106	the	the	DET
can-224	162	107	body	body	NOUN
can-224	162	108	to	to	PART
can-224	162	109	monitor	monitor	VERB
can-224	162	110	the	the	DET
can-224	162	111	disease	disease	NOUN
can-224	162	112	.	.	PUNCT
can-224	163	1	5	5	X
can-224	163	2	.	.	X
can-224	163	3	conclusion	conclusion	VERB
can-224	163	4	the	the	DET
can-224	163	5	direction	direction	NOUN
can-224	163	6	of	of	ADP
can-224	163	7	exploration	exploration	NOUN
can-224	163	8	of	of	ADP
can-224	163	9	nano	nano	NOUN
can-224	163	10	-	-	PUNCT
can-224	163	11	drug	drug	NOUN
can-224	163	12	carriers	carrier	NOUN
can-224	163	13	is	be	AUX
can-224	163	14	to	to	PART
can-224	163	15	be	be	AUX
can-224	163	16	intelligent	intelligent	ADJ
can-224	163	17	,	,	PUNCT
can-224	163	18	the	the	DET
can-224	163	19	study	study	NOUN
can-224	163	20	of	of	ADP
can-224	163	21	the	the	DET
can-224	163	22	preparation	preparation	NOUN
can-224	163	23	of	of	ADP
can-224	163	24	nano	nano	NOUN
can-224	163	25	-	-	PUNCT
can-224	163	26	carrier	carrier	NOUN
can-224	163	27	and	and	CCONJ
can-224	163	28	a	a	DET
can-224	163	29	specifi	specifi	PROPN
can-224	163	30	c	c	PROPN
can-224	163	31	drug	drug	NOUN
can-224	163	32	combination	combination	NOUN
can-224	163	33	to	to	PART
can-224	163	34	get	get	VERB
can-224	163	35	with	with	ADP
can-224	163	36	automatic	automatic	ADJ
can-224	163	37	targeting	targeting	NOUN
can-224	163	38	and	and	CCONJ
can-224	163	39	quantitative	quantitative	ADJ
can-224	163	40	timing	timing	NOUN
can-224	163	41	of	of	ADP
can-224	163	42	the	the	DET
can-224	163	43	release	release	NOUN
can-224	163	44	of	of	ADP
can-224	163	45	nano	nano	NOUN
can-224	163	46	-	-	PUNCT
can-224	163	47	intelligent	intelligent	ADJ
can-224	163	48	drugs	drug	NOUN
can-224	163	49	to	to	PART
can-224	163	50	address	address	VERB
can-224	163	51	the	the	DET
can-224	163	52	diagnosis	diagnosis	NOUN
can-224	163	53	and	and	CCONJ
can-224	163	54	treatment	treatment	NOUN
can-224	163	55	of	of	ADP
can-224	163	56	major	major	ADJ
can-224	163	57	diseases	disease	NOUN
can-224	163	58	.	.	PUNCT
can-224	164	1	the	the	DET
can-224	164	2	application	application	NOUN
can-224	164	3	of	of	ADP
can-224	164	4	nanotechnology	nanotechnology	NOUN
can-224	164	5	in	in	ADP
can-224	164	6	the	the	DET
can-224	164	7	field	field	NOUN
can-224	164	8	of	of	ADP
can-224	164	9	biopharmaceuticals	biopharmaceutical	NOUN
can-224	164	10	is	be	AUX
can-224	164	11	one	one	NUM
can-224	164	12	of	of	ADP
can-224	164	13	the	the	DET
can-224	164	14	most	most	ADV
can-224	164	15	promising	promising	ADJ
can-224	164	16	research	research	NOUN
can-224	164	17	directions	direction	NOUN
can-224	164	18	for	for	ADP
can-224	164	19	nanotechnology	nanotechnology	NOUN
can-224	164	20	in	in	ADP
can-224	164	21	the	the	DET
can-224	164	22	21st	21st	ADJ
can-224	164	23	century	century	NOUN
can-224	164	24	.	.	PUNCT
can-224	165	1	the	the	DET
can-224	165	2	use	use	NOUN
can-224	165	3	of	of	ADP
can-224	165	4	nano	nano	NOUN
can-224	165	5	-	-	PUNCT
can-224	165	6	drug	drug	NOUN
can-224	165	7	carriers	carrier	NOUN
can-224	165	8	makes	make	VERB
can-224	165	9	some	some	PRON
can-224	165	10	of	of	ADP
can-224	165	11	the	the	DET
can-224	165	12	better	well	ADJ
can-224	165	13	effi	effi	PROPN
can-224	165	14	cacy	cacy	NOUN
can-224	165	15	but	but	CCONJ
can-224	165	16	diffi	diffi	NOUN
can-224	165	17	cult	cult	NOUN
can-224	165	18	to	to	PART
can-224	165	19	dissolve	dissolve	VERB
can-224	165	20	,	,	PUNCT
can-224	165	21	slow	slow	ADJ
can-224	165	22	to	to	PART
can-224	165	23	dissolve	dissolve	VERB
can-224	165	24	,	,	PUNCT
can-224	165	25	highly	highly	ADV
can-224	165	26	toxic	toxic	ADJ
can-224	165	27	,	,	PUNCT
can-224	165	28	easily	easily	ADV
can-224	165	29	degradable	degradable	ADJ
can-224	165	30	in	in	ADP
can-224	165	31	the	the	DET
can-224	165	32	body	body	NOUN
can-224	165	33	of	of	ADP
can-224	165	34	the	the	DET
can-224	165	35	drug	drug	NOUN
can-224	165	36	has	have	AUX
can-224	165	37	been	be	AUX
can-224	165	38	applied	apply	VERB
can-224	165	39	to	to	ADP
can-224	165	40	fi	fi	NOUN
can-224	165	41	nd	nd	ADP
can-224	165	42	a	a	DET
can-224	165	43	new	new	ADJ
can-224	165	44	drug	drug	NOUN
can-224	165	45	dosage	dosage	NOUN
can-224	165	46	form	form	NOUN
can-224	165	47	of	of	ADP
can-224	165	48	excellent	excellent	ADJ
can-224	165	49	performance	performance	NOUN
can-224	165	50	,	,	PUNCT
can-224	165	51	its	its	PRON
can-224	165	52	signifi	signifi	NOUN
can-224	165	53	cance	cance	NOUN
can-224	165	54	is	be	AUX
can-224	165	55	no	no	PRON
can-224	165	56	less	less	ADJ
can-224	165	57	than	than	SCONJ
can-224	165	58	found	find	VERB
can-224	165	59	new	new	ADJ
can-224	165	60	drugs	drug	NOUN
can-224	165	61	.	.	PUNCT
can-224	166	1	now	now	ADV
can-224	166	2	,	,	PUNCT
can-224	166	3	there	there	PRON
can-224	166	4	are	be	VERB
can-224	166	5	several	several	ADJ
can-224	166	6	kinds	kind	NOUN
can-224	166	7	of	of	ADP
can-224	166	8	nano	nano	NOUN
can-224	166	9	-	-	PUNCT
can-224	166	10	drugs	drug	NOUN
can-224	166	11	into	into	ADP
can-224	166	12	commercial	commercial	ADJ
can-224	166	13	production	production	NOUN
can-224	166	14	,	,	PUNCT
can-224	166	15	not	not	PART
can-224	166	16	only	only	ADV
can-224	166	17	to	to	ADP
can-224	166	18	human	human	ADJ
can-224	166	19	disease	disease	NOUN
can-224	166	20	to	to	PART
can-224	166	21	bring	bring	VERB
can-224	166	22	a	a	DET
can-224	166	23	new	new	ADJ
can-224	166	24	gospel	gospel	NOUN
can-224	166	25	,	,	PUNCT
can-224	166	26	but	but	CCONJ
can-224	166	27	also	also	ADV
can-224	166	28	created	create	VERB
can-224	166	29	a	a	DET
can-224	166	30	considerable	considerable	ADJ
can-224	166	31	economic	economic	ADJ
can-224	166	32	benefi	benefi	NOUN
can-224	166	33	ts	ts	PROPN
can-224	166	34	.	.	PUNCT
can-224	167	1	but	but	CCONJ
can-224	167	2	the	the	DET
can-224	167	3	development	development	NOUN
can-224	167	4	of	of	ADP
can-224	167	5	nano	nano	NOUN
can-224	167	6	-	-	PUNCT
can-224	167	7	drugs	drug	NOUN
can-224	167	8	has	have	VERB
can-224	167	9	many	many	ADJ
can-224	167	10	problems	problem	NOUN
can-224	167	11	to	to	PART
can-224	167	12	be	be	AUX
can-224	167	13	solved	solve	VERB
can-224	167	14	,	,	PUNCT
can-224	167	15	such	such	ADJ
can-224	167	16	as	as	ADP
can-224	167	17	nanodrugs	nanodrug	NOUN
can-224	167	18	into	into	ADP
can-224	167	19	the	the	DET
can-224	167	20	human	human	ADJ
can-224	167	21	body	body	NOUN
can-224	167	22	,	,	PUNCT
can-224	167	23	in	in	ADP
can-224	167	24	the	the	DET
can-224	167	25	human	human	ADJ
can-224	167	26	body	body	NOUN
can-224	167	27	under	under	ADP
can-224	167	28	complex	complex	ADJ
can-224	167	29	biological	biological	ADJ
can-224	167	30	environment	environment	NOUN
can-224	167	31	,	,	PUNCT
can-224	167	32	drug	drug	NOUN
can-224	167	33	distribution	distribution	NOUN
can-224	167	34	,	,	PUNCT
can-224	167	35	degradation	degradation	NOUN
can-224	167	36	advances	advance	NOUN
can-224	167	37	in	in	ADP
can-224	167	38	synthesis	synthesis	NOUN
can-224	167	39	and	and	CCONJ
can-224	167	40	application	application	NOUN
can-224	167	41	of	of	ADP
can-224	167	42	nanometer	nanometer	NOUN
can-224	167	43	drug	drug	NOUN
can-224	167	44	carriers	carrier	NOUN
can-224	167	45	18	18	NUM
can-224	167	46	and	and	CCONJ
can-224	167	47	drug	drug	NOUN
can-224	167	48	release	release	NOUN
can-224	167	49	process	process	NOUN
can-224	167	50	,	,	PUNCT
can-224	167	51	the	the	DET
can-224	167	52	mechanism	mechanism	NOUN
can-224	167	53	of	of	ADP
can-224	167	54	drug	drug	NOUN
can-224	167	55	action	action	NOUN
can-224	167	56	,	,	PUNCT
can-224	167	57	drug	drug	NOUN
can-224	167	58	on	on	ADP
can-224	167	59	human	human	ADJ
can-224	167	60	function	function	NOUN
can-224	167	61	,	,	PUNCT
can-224	167	62	metabolism	metabolism	NOUN
can-224	167	63	,	,	PUNCT
can-224	167	64	structure	structure	NOUN
can-224	167	65	and	and	CCONJ
can-224	167	66	other	other	ADJ
can-224	167	67	issues	issue	NOUN
can-224	167	68	such	such	ADJ
can-224	167	69	as	as	ADP
can-224	167	70	the	the	DET
can-224	167	71	impact	impact	NOUN
can-224	167	72	of	of	ADP
can-224	167	73	research	research	NOUN
can-224	167	74	is	be	AUX
can-224	167	75	not	not	PART
can-224	167	76	thorough	thorough	ADJ
can-224	167	77	enough	enough	ADV
can-224	167	78	.	.	PUNCT
can-224	168	1	the	the	DET
can-224	168	2	current	current	ADJ
can-224	168	3	research	research	NOUN
can-224	168	4	and	and	CCONJ
can-224	168	5	development	development	NOUN
can-224	168	6	trends	trend	NOUN
can-224	168	7	are	be	AUX
can-224	168	8	mainly	mainly	ADV
can-224	168	9	focused	focus	VERB
can-224	168	10	on	on	ADP
can-224	168	11	the	the	DET
can-224	168	12	following	follow	VERB
can-224	168	13	aspects	aspect	NOUN
can-224	168	14	:	:	PUNCT
can-224	168	15	fi	fi	NOUN
can-224	168	16	nding	nde	VERB
can-224	168	17	new	new	ADJ
can-224	168	18	methods	method	NOUN
can-224	168	19	for	for	ADP
can-224	168	20	the	the	DET
can-224	168	21	preparation	preparation	NOUN
can-224	168	22	of	of	ADP
can-224	168	23	nano	nano	NOUN
can-224	168	24	-	-	PUNCT
can-224	168	25	materials	material	NOUN
can-224	168	26	;	;	PUNCT
can-224	168	27	synthesizing	synthesize	VERB
can-224	168	28	and	and	CCONJ
can-224	168	29	discovering	discover	VERB
can-224	168	30	new	new	ADJ
can-224	168	31	non	non	ADJ
can-224	168	32	-	-	ADJ
can-224	168	33	toxic	toxic	ADJ
can-224	168	34	or	or	CCONJ
can-224	168	35	micro	micro	NOUN
can-224	168	36	-	-	ADJ
can-224	168	37	toxic	toxic	ADJ
can-224	168	38	,	,	PUNCT
can-224	168	39	biocompatible	biocompatible	ADJ
can-224	168	40	and	and	CCONJ
can-224	168	41	biodegradable	biodegradable	ADJ
can-224	168	42	nano	nano	NOUN
can-224	168	43	-	-	PUNCT
can-224	168	44	drug	drug	NOUN
can-224	168	45	carriers	carrier	NOUN
can-224	168	46	;	;	PUNCT
can-224	168	47	to	to	PART
can-224	168	48	improve	improve	VERB
can-224	168	49	the	the	DET
can-224	168	50	targeting	targeting	NOUN
can-224	168	51	and	and	CCONJ
can-224	168	52	sustainedrelease	sustainedrelease	NOUN
can-224	168	53	properties	property	NOUN
can-224	168	54	,	,	PUNCT
can-224	168	55	stability	stability	NOUN
can-224	168	56	,	,	PUNCT
can-224	168	57	drug	drug	NOUN
can-224	168	58	loading	loading	NOUN
can-224	168	59	,	,	PUNCT
can-224	168	60	and	and	CCONJ
can-224	168	61	gradually	gradually	ADV
can-224	168	62	realize	realize	VERB
can-224	168	63	the	the	DET
can-224	168	64	intelligence	intelligence	NOUN
can-224	168	65	of	of	ADP
can-224	168	66	the	the	DET
can-224	168	67	drug	drug	NOUN
can-224	168	68	;	;	PUNCT
can-224	168	69	study	study	VERB
can-224	168	70	the	the	DET
can-224	168	71	mechanism	mechanism	NOUN
can-224	168	72	of	of	ADP
can-224	168	73	drug	drug	NOUN
can-224	168	74	action	action	NOUN
can-224	168	75	,	,	PUNCT
can-224	168	76	the	the	DET
can-224	168	77	development	development	NOUN
can-224	168	78	of	of	ADP
can-224	168	79	nano	nano	NOUN
can-224	168	80	-	-	PUNCT
can-224	168	81	drug	drug	NOUN
can-224	168	82	carrier	carrier	NOUN
can-224	168	83	in	in	ADP
can-224	168	84	vitro	vitro	X
can-224	168	85	and	and	CCONJ
can-224	168	86	in	in	ADP
can-224	168	87	vivo	vivo	ADJ
can-224	168	88	detection	detection	NOUN
can-224	168	89	technology	technology	NOUN
can-224	168	90	.	.	PUNCT
can-224	169	1	references	reference	NOUN
can-224	169	2	1	1	NUM
can-224	169	3	.	.	PUNCT
can-224	170	1	lu	lu	PROPN
can-224	170	2	w	w	PROPN
can-224	170	3	,	,	PUNCT
can-224	170	4	i	i	PRON
can-224	170	5	zhangy	zhangy	NOUN
can-224	170	6	,	,	PUNCT
can-224	170	7	tanyz	tanyz	ADV
can-224	170	8	,	,	PUNCT
can-224	170	9	et	et	NOUN
can-224	170	10	a1	a1	PROPN
can-224	170	11	.	.	PUNCT
can-224	170	12	cationic	cationic	ADJ
can-224	170	13	albumin	albumin	NOUN
can-224	170	14	-	-	PUNCT
can-224	170	15	conjugated	conjugate	VERB
can-224	170	16	pegylated	pegylated	ADJ
can-224	170	17	nanoparticles	nanoparticle	NOUN
can-224	170	18	as	as	ADP
can-224	170	19	novel	novel	ADJ
can-224	170	20	drug	drug	NOUN
can-224	170	21	carrier	carrier	NOUN
can-224	170	22	forbrain	forbrain	NOUN
can-224	170	23	delivery	delivery	NOUN
can-224	171	1	[	[	X
can-224	171	2	j	j	X
can-224	171	3	]	]	X
can-224	171	4	.	.	PUNCT
can-224	172	1	j	j	PROPN
can-224	172	2	controlled	control	VERB
can-224	172	3	release	release	NOUN
can-224	172	4	,	,	PUNCT
can-224	172	5	2005	2005	NUM
can-224	172	6	,	,	PUNCT
can-224	172	7	107	107	NUM
can-224	172	8	(	(	PUNCT
can-224	172	9	3	3	NUM
can-224	172	10	):	):	PUNCT
can-224	172	11	428	428	NUM
can-224	172	12	.	.	NOUN
can-224	173	1	2	2	NUM
can-224	173	2	.	.	X
can-224	173	3	cx	cx	PROPN
can-224	173	4	.	.	PUNCT
can-224	174	1	yi	yi	PROPN
can-224	174	2	,	,	PUNCT
can-224	174	3	jn	jn	PROPN
can-224	174	4	.	.	PROPN
can-224	174	5	yu	yu	PROPN
can-224	174	6	,	,	PUNCT
can-224	174	7	xm	xm	PROPN
can-224	174	8	.	.	PUNCT
can-224	175	1	xu	xu	PROPN
can-224	175	2	.	.	PUNCT
can-224	176	1	nano	nano	NOUN
can-224	176	2	drug	drug	NOUN
can-224	176	3	carrier	carrier	NOUN
can-224	176	4	in	in	ADP
can-224	176	5	the	the	DET
can-224	176	6	development	development	NOUN
can-224	176	7	of	of	ADP
can-224	176	8	traditional	traditional	ADJ
can-224	176	9	chinese	chinese	ADJ
can-224	176	10	medicine	medicine	NOUN
can-224	176	11	jing	jing	NOUN
can-224	176	12	of	of	ADP
can-224	176	13	the	the	DET
can-224	176	14	application	application	NOUN
can-224	176	15	[	[	X
can-224	176	16	j	j	X
can-224	176	17	]	]	X
can-224	176	18	.	.	PUNCT
can-224	177	1	chinese	chinese	ADJ
can-224	177	2	journal	journal	PROPN
can-224	177	3	of	of	ADP
can-224	177	4	traditional	traditional	ADJ
can-224	177	5	chinese	chinese	ADJ
can-224	177	6	medicine	medicine	NOUN
can-224	177	7	,	,	PUNCT
can-224	177	8	2008,33	2008,33	PROPN
can-224	177	9	(	(	PUNCT
can-224	177	10	16	16	NUM
can-224	177	11	):	):	PUNCT
can-224	177	12	1936	1936	NUM
can-224	177	13	-	-	SYM
can-224	177	14	1940	1940	NUM
can-224	177	15	.	.	PUNCT
can-224	178	1	3	3	X
can-224	178	2	.	.	X
can-224	178	3	kreuter	kreuter	PROPN
can-224	178	4	j	j	PROPN
can-224	178	5	,	,	PUNCT
can-224	178	6	hekmatara	hekmatara	PROPN
can-224	178	7	t	t	PROPN
can-224	178	8	,	,	PUNCT
can-224	178	9	dreis	dreis	PROPN
can-224	178	10	s	s	PROPN
can-224	178	11	,	,	PUNCT
can-224	178	12	et	et	PROPN
can-224	178	13	al	al	PROPN
can-224	178	14	.	.	PROPN
can-224	178	15	covalent	covalent	ADJ
can-224	178	16	attachment	attachment	NOUN
can-224	178	17	of	of	ADP
can-224	178	18	apo	apo	PROPN
can-224	178	19	lipoprotein	lipoprotein	PROPN
can-224	178	20	a	a	PRON
can-224	178	21	-	-	PUNCT
can-224	178	22	i	i	NOUN
can-224	178	23	and	and	CCONJ
can-224	178	24	apo	apo	PROPN
can-224	178	25	lipoprotein	lipoprotein	PROPN
can-224	178	26	b	b	NOUN
can-224	178	27	-	-	PUNCT
can-224	178	28	loo	loo	NOUN
can-224	178	29	to	to	ADP
can-224	178	30	albumin	albumin	ADJ
can-224	178	31	nanoparticles	nanoparticle	NOUN
can-224	178	32	enables	enable	VERB
can-224	178	33	drug	drug	NOUN
can-224	178	34	transport	transport	NOUN
can-224	178	35	into	into	ADP
can-224	178	36	the	the	DET
can-224	178	37	brain	brain	NOUN
can-224	178	38	l	l	PROPN
can-224	178	39	-	-	PROPN
can-224	178	40	j	j	X
can-224	178	41	]	]	X
can-224	178	42	.	.	PUNCT
can-224	179	1	j	j	PROPN
can-224	179	2	controlled	control	VERB
can-224	179	3	release	release	NOUN
can-224	179	4	,	,	PUNCT
can-224	179	5	2007	2007	NUM
can-224	179	6	,	,	PUNCT
can-224	179	7	118	118	NUM
can-224	179	8	(	(	PUNCT
can-224	179	9	1	1	NUM
can-224	179	10	):	):	PUNCT
can-224	179	11	54	54	NUM
can-224	179	12	.	.	X
can-224	180	1	4	4	NUM
can-224	180	2	.	.	X
can-224	180	3	yang	yang	PROPN
can-224	180	4	,	,	PUNCT
can-224	180	5	wl	wl	PROPN
can-224	180	6	.	.	PROPN
can-224	180	7	lu	lu	PROPN
can-224	180	8	,	,	PUNCT
can-224	180	9	q.	q.	PROPN
can-224	180	10	zhang	zhang	PROPN
can-224	180	11	.	.	PROPN
can-224	180	12	advances	advance	NOUN
can-224	180	13	in	in	ADP
can-224	180	14	liposomal	liposomal	NOUN
can-224	180	15	and	and	CCONJ
can-224	180	16	nanoparticle	nanoparticle	NOUN
can-224	180	17	drug	drug	NOUN
can-224	180	18	delivery	delivery	NOUN
can-224	180	19	systems	system	NOUN
can-224	180	20	ej3	ej3	PROPN
can-224	180	21	.	.	PUNCT
can-224	181	1	chinese	chinese	ADJ
can-224	181	2	journal	journal	PROPN
can-224	181	3	of	of	ADP
can-224	181	4	medical	medical	ADJ
can-224	181	5	science	science	NOUN
can-224	181	6	,	,	PUNCT
can-224	181	7	2006,28	2006,28	NUM
can-224	181	8	(	(	PUNCT
can-224	181	9	4	4	NUM
can-224	181	10	):	):	PUNCT
can-224	181	11	583	583	NUM
can-224	181	12	-	-	SYM
can-224	181	13	589	589	NUM
can-224	181	14	.	.	PUNCT
can-224	182	1	5	5	NUM
can-224	182	2	.	.	X
can-224	182	3	bp	bp	PROPN
can-224	182	4	.	.	PUNCT
can-224	183	1	yang	yang	PROPN
can-224	183	2	,	,	PUNCT
can-224	183	3	wq	wq	PROPN
can-224	183	4	.	.	PUNCT
can-224	183	5	ouyang	ouyang	PROPN
can-224	183	6	,	,	PUNCT
can-224	183	7	xj	xj	PROPN
can-224	183	8	.	.	PROPN
can-224	183	9	wu	wu	PROPN
can-224	183	10	.	.	PUNCT
can-224	184	1	wait	wait	VERB
can-224	184	2	.	.	PUNCT
can-224	185	1	the	the	DET
can-224	185	2	quality	quality	NOUN
can-224	185	3	evaluation	evaluation	NOUN
can-224	185	4	of	of	ADP
can-224	185	5	resveratrol	resveratrol	NOUN
can-224	185	6	nano	nano	NOUN
can-224	185	7	emulsion	emulsion	NOUN
can-224	185	8	[	[	X
can-224	185	9	j	j	X
can-224	185	10	]	]	X
can-224	185	11	.	.	PUNCT
can-224	186	1	journal	journal	PROPN
can-224	186	2	of	of	ADP
can-224	186	3	northwest	northwest	PROPN
can-224	186	4	agricultural	agricultural	ADJ
can-224	186	5	sciences	science	NOUN
can-224	186	6	2008,17	2008,17	NUM
can-224	186	7	(	(	PUNCT
can-224	186	8	2	2	NUM
can-224	186	9	):	):	PUNCT
can-224	186	10	20	20	NUM
can-224	186	11	-	-	SYM
can-224	186	12	23	23	NUM
can-224	186	13	.	.	PUNCT
can-224	187	1	6	6	NUM
can-224	187	2	.	.	X
can-224	187	3	hy	hy	PROPN
can-224	187	4	.	.	PUNCT
can-224	188	1	lin	lin	PROPN
can-224	188	2	,	,	PUNCT
can-224	188	3	xy	xy	PROPN
can-224	188	4	.	.	PUNCT
can-224	189	1	lu	lu	PROPN
can-224	189	2	,	,	PUNCT
can-224	189	3	n.	n.	PROPN
can-224	189	4	tang	tang	PROPN
can-224	189	5	,	,	PUNCT
can-224	189	6	et	et	PROPN
can-224	189	7	al	al	PROPN
can-224	189	8	.	.	PUNCT
can-224	189	9	preparation	preparation	NOUN
can-224	189	10	of	of	ADP
can-224	189	11	vincristine	vincristine	NOUN
can-224	189	12	pegpe	pegpe	NOUN
can-224	189	13	micelles	micelle	NOUN
can-224	189	14	and	and	CCONJ
can-224	189	15	its	its	PRON
can-224	189	16	inhibition	inhibition	NOUN
can-224	189	17	on	on	ADP
can-224	189	18	breast	breast	NOUN
can-224	189	19	cancer	cancer	NOUN
can-224	189	20	cell	cell	NOUN
can-224	189	21	growth	growth	NOUN
can-224	189	22	[	[	X
can-224	189	23	j3	j3	PROPN
can-224	189	24	]	]	PUNCT
can-224	189	25	.	.	PUNCT
can-224	190	1	biochemistry	biochemistry	NOUN
can-224	190	2	and	and	CCONJ
can-224	190	3	biophysical	biophysical	ADJ
can-224	190	4	advances	advance	NOUN
can-224	190	5	,	,	PUNCT
can-224	190	6	2006	2006	NUM
can-224	190	7	,	,	PUNCT
can-224	190	8	33	33	NUM
can-224	190	9	(	(	PUNCT
can-224	190	10	8)	8)	NUM
can-224	190	11	:	:	PUNCT
can-224	190	12	769	769	NUM
can-224	190	13	-	-	PUNCT
can-224	190	14	774	774	NUM
can-224	190	15	.	.	PUNCT
can-224	191	1	7	7	X
can-224	191	2	.	.	X
can-224	191	3	jacobs	jacobs	PROPN
can-224	191	4	c	c	PROPN
can-224	191	5	,	,	PUNCT
can-224	191	6	kayser	kayser	PROPN
can-224	191	7	o	o	PROPN
can-224	191	8	,	,	PUNCT
can-224	191	9	muller	muller	PROPN
can-224	191	10	rh	rh	PROPN
can-224	191	11	.	.	PROPN
can-224	191	12	production	production	NOUN
can-224	191	13	and	and	CCONJ
can-224	191	14	characterization	characterization	NOUN
can-224	191	15	of	of	ADP
can-224	191	16	mucoadhesive	mucoadhesive	ADJ
can-224	191	17	nano	nano	NOUN
can-224	191	18	suspensions	suspension	NOUN
can-224	191	19	for	for	ADP
can-224	191	20	the	the	DET
can-224	191	21	formulation	formulation	NOUN
can-224	191	22	of	of	ADP
can-224	191	23	bupravaquone	bupravaquone	NOUN
can-224	192	1	[	[	X
can-224	192	2	j	j	X
can-224	192	3	]	]	X
can-224	192	4	.	.	PUNCT
can-224	193	1	int	int	PROPN
can-224	193	2	j	j	PROPN
can-224	193	3	pharm	pharm	PROPN
can-224	193	4	,	,	PUNCT
can-224	193	5	2001	2001	NUM
can-224	193	6	,	,	PUNCT
can-224	193	7	214	214	NUM
can-224	193	8	:	:	PUNCT
can-224	193	9	3	3	NUM
can-224	193	10	.	.	NOUN
can-224	193	11	8	8	NUM
can-224	193	12	.	.	PUNCT
can-224	194	1	guo	guo	PROPN
can-224	194	2	,	,	PUNCT
can-224	194	3	sq	sq	PROPN
can-224	194	4	.	.	PROPN
can-224	194	5	deng	deng	PROPN
can-224	194	6	.	.	PUNCT
can-224	194	7	application	application	NOUN
can-224	194	8	of	of	ADP
can-224	194	9	nanotechnology	nanotechnology	NOUN
can-224	194	10	in	in	ADP
can-224	194	11	pharmacy	pharmacy	NOUN
can-224	194	12	research	research	NOUN
can-224	194	13	progress	progress	NOUN
can-224	194	14	.	.	PUNCT
can-224	195	1	foreign	foreign	ADJ
can-224	195	2	medical	medical	ADJ
can-224	195	3	antibiotics	antibiotic	NOUN
can-224	195	4	volume	volume	NOUN
can-224	195	5	,	,	PUNCT
can-224	195	6	2004,25	2004,25	NUM
can-224	195	7	(	(	PUNCT
can-224	195	8	5	5	NUM
can-224	195	9	)	)	PUNCT
can-224	195	10	;	;	PUNCT
can-224	195	11	233	233	NUM
can-224	195	12	-	-	SYM
can-224	195	13	237	237	NUM
can-224	195	14	.	.	PUNCT
can-224	196	1	9	9	X
can-224	196	2	.	.	X
can-224	196	3	fangc	fangc	NOUN
can-224	196	4	,	,	PUNCT
can-224	196	5	shib	shib	NOUN
can-224	196	6	,	,	PUNCT
can-224	196	7	peiyy	peiyy	NOUN
can-224	196	8	,	,	PUNCT
can-224	196	9	etal	etal	NOUN
can-224	196	10	.	.	PUNCT
can-224	197	1	in	in	ADP
can-224	197	2	vivo	vivo	ADJ
can-224	197	3	tumor	tumor	NOUN
can-224	197	4	targeting	target	VERB
can-224	197	5	of	of	ADP
can-224	197	6	tumor	tumor	NOUN
can-224	197	7	necrosis	necrosis	NOUN
can-224	197	8	factor2	factor2	ADJ
can-224	197	9	alpha2	alpha2	NOUN
can-224	197	10	loaded	load	VERB
can-224	197	11	stealth	stealth	ADJ
can-224	197	12	nanoparticles	nanoparticle	NOUN
can-224	197	13	:	:	PUNCT
can-224	197	14	effect	effect	NOUN
can-224	197	15	of	of	ADP
can-224	197	16	me2peg	me2peg	PROPN
can-224	197	17	molecular	molecular	ADJ
can-224	197	18	weight	weight	NOUN
can-224	197	19	ad	ad	NOUN
can-224	197	20	particle	particle	NOUN
can-224	197	21	size	size	NOUN
can-224	197	22	[	[	X
can-224	197	23	j	j	X
can-224	197	24	]	]	X
can-224	197	25	.	.	PUNCT
can-224	198	1	eur	eur	PROPN
can-224	198	2	j	j	PROPN
can-224	198	3	pharm	pharm	PROPN
can-224	198	4	sci	sci	PROPN
can-224	198	5	,	,	PUNCT
can-224	198	6	2006,27	2006,27	NUM
can-224	198	7	(	(	PUNCT
can-224	198	8	1	1	NUM
can-224	198	9	):	):	PUNCT
can-224	198	10	27236	27236	NUM
can-224	198	11	10	10	NUM
can-224	198	12	.	.	PUNCT
can-224	199	1	guangdong	guangdong	PROPN
can-224	199	2	medicine	medicine	PROPN
can-224	199	3	,	,	PUNCT
can-224	199	4	2009,30	2009,30	NUM
can-224	199	5	(	(	PUNCT
can-224	199	6	1	1	NUM
can-224	199	7	):	):	PUNCT
can-224	199	8	17219	17219	NUM
can-224	199	9	(	(	PUNCT
can-224	199	10	in	in	ADP
can-224	199	11	chinese	chinese	PROPN
can-224	199	12	with	with	ADP
can-224	199	13	english	english	PROPN
can-224	199	14	abstract	abstract	NOUN
can-224	199	15	)	)	PUNCT
can-224	200	1	[	[	X
can-224	200	2	j	j	X
can-224	200	3	]	]	X
can-224	200	4	.	.	PUNCT
can-224	201	1	11	11	NUM
can-224	201	2	.	.	PUNCT
can-224	202	1	wl	wl	PROPN
can-224	202	2	.	.	PUNCT
can-224	203	1	lu	lu	PROPN
can-224	203	2	,	,	PUNCT
can-224	203	3	jx	jx	PROPN
can-224	203	4	.	.	PUNCT
can-224	204	1	guo	guo	PROPN
can-224	204	2	,	,	PUNCT
can-224	204	3	qn	qn	PROPN
can-224	204	4	.	.	PROPN
can-224	204	5	ping	ping	PROPN
can-224	204	6	.	.	PUNCT
can-224	205	1	preparation	preparation	NOUN
can-224	205	2	and	and	CCONJ
can-224	205	3	quality	quality	NOUN
can-224	205	4	of	of	ADP
can-224	205	5	breviscapine	breviscapine	ADJ
can-224	205	6	liposomes	liposome	NOUN
can-224	206	1	[	[	X
can-224	206	2	j	j	X
can-224	206	3	]	]	X
can-224	206	4	.	.	PUNCT
can-224	207	1	chinese	chinese	ADJ
can-224	207	2	journal	journal	PROPN
can-224	207	3	of	of	ADP
can-224	207	4	natural	natural	ADJ
can-224	207	5	medicines	medicine	NOUN
can-224	207	6	,	,	PUNCT
can-224	207	7	2004	2004	NUM
can-224	207	8	,	,	PUNCT
can-224	207	9	2	2	NUM
can-224	207	10	,	,	PUNCT
can-224	207	11	(	(	PUNCT
can-224	207	12	5	5	NUM
can-224	207	13	)	)	PUNCT
can-224	207	14	12	12	NUM
can-224	207	15	.	.	PUNCT
can-224	208	1	y.	y.	PROPN
can-224	208	2	gu	gu	PROPN
can-224	208	3	,	,	PUNCT
can-224	208	4	y.	y.	PROPN
can-224	208	5	shi	shi	PROPN
can-224	208	6	,	,	PUNCT
can-224	208	7	sq	sq	PROPN
can-224	208	8	.	.	PROPN
can-224	208	9	zhang	zhang	PROPN
can-224	208	10	,	,	PUNCT
can-224	208	11	et	et	PROPN
can-224	208	12	al	al	PROPN
can-224	208	13	.	.	PUNCT
can-224	208	14	preparation	preparation	NOUN
can-224	208	15	and	and	CCONJ
can-224	208	16	quality	quality	NOUN
can-224	208	17	evaluation	evaluation	NOUN
can-224	208	18	of	of	ADP
can-224	208	19	emodinnano	emodinnano	NOUN
can-224	208	20	-	-	PUNCT
can-224	208	21	liposomes	liposome	NOUN
can-224	209	1	[	[	X
can-224	209	2	j	j	X
can-224	209	3	]	]	X
can-224	209	4	.	.	PUNCT
can-224	210	1	journal	journal	PROPN
can-224	210	2	of	of	ADP
can-224	210	3	the	the	DET
can-224	210	4	fourth	fourth	ADJ
can-224	210	5	military	military	PROPN
can-224	210	6	medical	medical	ADJ
can-224	210	7	university	university	NOUN
can-224	210	8	,	,	PUNCT
can-224	210	9	2003	2003	NUM
can-224	210	10	,	,	PUNCT
can-224	210	11	24	24	NUM
can-224	210	12	(	(	PUNCT
can-224	210	13	5	5	NUM
can-224	210	14	)	)	PUNCT
can-224	210	15	.	.	PUNCT
can-224	211	1	13	13	NUM
can-224	211	2	.	.	X
can-224	212	1	c	c	NOUN
can-224	212	2	hauvierre	hauvierre	VERB
can-224	213	1	c	c	NOUN
can-224	213	2	,	,	PUNCT
can-224	213	3	v	v	X
can-224	213	4	authier	authier	NOUN
can-224	213	5	c	c	NOUN
can-224	213	6	,	,	PUNCT
can-224	213	7	labarre	labarre	PROPN
can-224	213	8	detal	detal	PROPN
can-224	213	9	.	.	PUNCT
can-224	214	1	evaluation	evaluation	NOUN
can-224	214	2	of	of	ADP
can-224	214	3	the	the	DET
can-224	214	4	surface	surface	NOUN
can-224	214	5	properties	property	NOUN
can-224	214	6	of	of	ADP
can-224	214	7	dextran	dextran	ADJ
can-224	214	8	coated	coated	ADJ
can-224	214	9	poly	poly	ADJ
can-224	214	10	(	(	PUNCT
can-224	214	11	isobutylcyanoacry	isobutylcyanoacry	VERB
can-224	214	12	late	late	ADJ
can-224	214	13	)	)	PUNCT
can-224	214	14	nanoparticles	nanoparticle	NOUN
can-224	214	15	by	by	ADP
can-224	214	16	spin	spin	NOUN
can-224	214	17	-	-	PUNCT
can-224	214	18	labelling	labelling	NOUN
can-224	214	19	coupled	couple	VERB
can-224	214	20	with	with	ADP
can-224	214	21	electron	electron	NOUN
can-224	214	22	resonance	resonance	NOUN
can-224	214	23	spectroscopy	spectroscopy	NOUN
can-224	214	24	[	[	X
can-224	214	25	j	j	X
can-224	214	26	]	]	X
can-224	214	27	.	.	PUNCT
can-224	215	1	colloid	colloid	PROPN
can-224	215	2	polym	polym	PROPN
can-224	215	3	sci	sci	PROPN
can-224	215	4	,	,	PUNCT
can-224	215	5	2004	2004	NUM
can-224	215	6	,	,	PUNCT
can-224	215	7	282	282	NUM
can-224	215	8	:	:	SYM
can-224	215	9	1016	1016	NUM
can-224	215	10	-1025	-1025	ADJ
can-224	215	11	.	.	PUNCT
can-224	216	1	14	14	NUM
can-224	216	2	.	.	PUNCT
can-224	216	3	l.	l.	PROPN
can-224	216	4	wang	wang	PROPN
can-224	216	5	.	.	PUNCT
can-224	217	1	reverse	reverse	PROPN
can-224	217	2	micro	micro	NOUN
can-224	217	3	emulsion	emulsion	NOUN
can-224	217	4	polymerization	polymerization	NOUN
can-224	217	5	and	and	CCONJ
can-224	217	6	preparation	preparation	NOUN
can-224	217	7	of	of	ADP
can-224	217	8	magnetic	magnetic	ADJ
can-224	217	9	polymer	polymer	NOUN
can-224	217	10	nanoparticles	nanoparticle	NOUN
can-224	217	11	[	[	X
can-224	217	12	d	d	X
can-224	217	13	]	]	X
can-224	217	14	.	.	PUNCT
can-224	218	1	shanghai	shanghai	PROPN
can-224	218	2	:	:	PUNCT
can-224	218	3	fudan	fudan	PROPN
can-224	218	4	university	university	PROPN
can-224	218	5	,	,	PUNCT
can-224	218	6	2001	2001	NUM
can-224	218	7	.	.	PUNCT
can-224	219	1	15	15	NUM
can-224	219	2	.	.	PUNCT
can-224	219	3	yq	yq	PROPN
can-224	219	4	.	.	PUNCT
can-224	219	5	liao	liao	PROPN
can-224	219	6	.	.	PUNCT
can-224	219	7	methyl	methyl	NOUN
can-224	219	8	methacrylate	methacrylate	NOUN
can-224	219	9	emulsion	emulsion	NOUN
can-224	219	10	and	and	CCONJ
can-224	219	11	micro	micro	ADJ
can-224	219	12	emulsion	emulsion	NOUN
can-224	219	13	ultrasonic	ultrasonic	ADJ
can-224	219	14	irradiation	irradiation	NOUN
can-224	219	15	initiation	initiation	NOUN
can-224	219	16	polymerization	polymerization	NOUN
can-224	219	17	and	and	CCONJ
can-224	219	18	synthesis	synthesis	NOUN
can-224	219	19	with	with	ADP
can-224	219	20	inorganic	inorganic	ADJ
can-224	219	21	nanoparticles	nanoparticle	NOUN
can-224	220	1	[	[	X
can-224	220	2	d	d	X
can-224	220	3	]	]	X
can-224	220	4	.	.	PUNCT
can-224	221	1	chengdu	chengdu	PROPN
can-224	221	2	:	:	PUNCT
can-224	221	3	sichuan	sichuan	PROPN
can-224	221	4	university	university	PROPN
can-224	221	5	,	,	PUNCT
can-224	221	6	2001	2001	NUM
can-224	221	7	.	.	PUNCT
can-224	222	1	16	16	NUM
can-224	222	2	.	.	PUNCT
can-224	223	1	cx	cx	PROPN
can-224	223	2	.	.	PUNCT
can-224	224	1	li	li	PROPN
can-224	224	2	,	,	PUNCT
can-224	224	3	zh	zh	PROPN
can-224	224	4	.	.	PUNCT
can-224	224	5	wang	wang	PROPN
can-224	224	6	.	.	PUNCT
can-224	225	1	application	application	NOUN
can-224	225	2	of	of	ADP
can-224	225	3	ultrasonic	ultrasonic	ADJ
can-224	225	4	technology	technology	NOUN
can-224	225	5	in	in	ADP
can-224	225	6	preparation	preparation	NOUN
can-224	225	7	of	of	ADP
can-224	225	8	nanomaterials	nanomaterial	NOUN
can-224	225	9	[	[	X
can-224	225	10	j	j	X
can-224	225	11	]	]	X
can-224	225	12	.	.	PUNCT
can-224	226	1	chemical	chemical	PROPN
can-224	226	2	bulletin	bulletin	PROPN
can-224	226	3	,	,	PUNCT
can-224	226	4	2001	2001	NUM
can-224	226	5	,	,	PUNCT
can-224	226	6	5	5	NUM
can-224	226	7	:	:	SYM
can-224	226	8	268	268	NUM
can-224	226	9	271	271	NUM
can-224	226	10	.	.	PUNCT
can-224	227	1	17	17	NUM
can-224	227	2	.	.	PUNCT
can-224	227	3	pilar	pilar	PROPN
can-224	227	4	calvo	calvo	PROPN
can-224	227	5	,	,	PUNCT
can-224	227	6	jose	jose	PROPN
can-224	227	7	'	'	PART
can-224	227	8	l.	l.	PROPN
can-224	227	9	vidla	vidla	PROPN
can-224	227	10	-	-	PUNCT
can-224	227	11	jato	jato	PROPN
can-224	227	12	,	,	PUNCT
can-224	227	13	maria	maria	PROPN
can-224	227	14	jalonso	jalonso	PROPN
can-224	227	15	.	.	PUNCT
can-224	228	1	evaluation	evaluation	NOUN
can-224	228	2	of	of	ADP
can-224	228	3	cationic	cationic	ADJ
can-224	228	4	polymer	polymer	NOUN
can-224	228	5	-	-	PUNCT
can-224	228	6	coated	coat	VERB
can-224	228	7	nanocapsules	nanocapsule	NOUN
can-224	228	8	as	as	ADP
can-224	228	9	ocular	ocular	ADJ
can-224	228	10	drug	drug	NOUN
can-224	228	11	carriers	carrier	NOUN
can-224	228	12	[	[	X
can-224	228	13	j	j	X
can-224	228	14	]	]	X
can-224	228	15	.	.	PUNCT
can-224	229	1	international	international	ADJ
can-224	229	2	journal	journal	PROPN
can-224	229	3	of	of	ADP
can-224	229	4	pharmaceutics	pharmaceutic	NOUN
can-224	229	5	,	,	PUNCT
can-224	229	6	1997	1997	NUM
can-224	229	7	,	,	PUNCT
can-224	229	8	53	53	NUM
can-224	229	9	:	:	SYM
can-224	229	10	41	41	NUM
can-224	229	11	-50	-50	NUM
can-224	229	12	.	.	PUNCT
can-224	230	1	18	18	NUM
can-224	230	2	.	.	PUNCT
can-224	230	3	soma	soma	PROPN
can-224	230	4	ce	ce	PROPN
can-224	230	5	,	,	PUNCT
can-224	230	6	dubernet	dubernet	PROPN
can-224	230	7	c	c	PROPN
can-224	230	8	,	,	PUNCT
can-224	230	9	baratt	baratt	ADJ
can-224	230	10	g.	g.	PROPN
can-224	230	11	ability	ability	NOUN
can-224	230	12	of	of	ADP
can-224	230	13	doxorubicin	doxorubicin	PROPN
can-224	230	14	-	-	PUNCT
can-224	230	15	loaded	load	VERB
can-224	230	16	nanoparticles	nanoparticle	NOUN
can-224	230	17	to	to	PART
can-224	230	18	overcome	overcome	VERB
can-224	230	19	multidrug	multidrug	NOUN
can-224	230	20	resistance	resistance	NOUN
can-224	230	21	of	of	ADP
can-224	230	22	tumor	tumor	NOUN
can-224	230	23	cells	cell	NOUN
can-224	230	24	after	after	ADP
can-224	230	25	their	their	PRON
can-224	230	26	capture	capture	NOUN
can-224	230	27	by	by	ADP
can-224	230	28	macrophages	macrophage	NOUN
can-224	230	29	.	.	PUNCT
can-224	231	1	pharm	pharm	NOUN
can-224	231	2	research	research	PROPN
can-224	231	3	.	.	PUNCT
can-224	232	1	1999	1999	NUM
can-224	232	2	;	;	PUNCT
can-224	232	3	16	16	NUM
can-224	232	4	(	(	PUNCT
can-224	232	5	11	11	NUM
can-224	232	6	):	):	PUNCT
can-224	232	7	1710	1710	NUM
can-224	232	8	.	.	PUNCT
can-224	233	1	19	19	NUM
can-224	233	2	.	.	X
can-224	233	3	kou	kou	PROPN
can-224	233	4	g	g	PROPN
can-224	233	5	,	,	PUNCT
can-224	233	6	gao	gao	PROPN
can-224	233	7	j.	j.	PROPN
can-224	233	8	wang	wang	PROPN
can-224	233	9	h.	h.	PROPN
can-224	233	10	preparation	preparation	NOUN
can-224	233	11	and	and	CCONJ
can-224	233	12	characterization	characterization	NOUN
can-224	233	13	of	of	ADP
can-224	233	14	paditaxel	paditaxel	NOUN
can-224	233	15	-	-	PUNCT
can-224	233	16	loaded	load	VERB
can-224	233	17	plga	plga	NOUN
can-224	233	18	nanoparticles	nanoparticle	NOUN
can-224	233	19	coated	coat	VERB
can-224	233	20	with	with	ADP
can-224	233	21	cationic	cationic	ADJ
can-224	233	22	sm5	sm5	X
can-224	233	23	-	-	PUNCT
can-224	233	24	1	1	NUM
can-224	233	25	single	single	ADJ
can-224	233	26	-	-	PUNCT
can-224	233	27	chain	chain	NOUN
can-224	233	28	antibody	antibody	NOUN
can-224	233	29	.	.	PUNCT
can-224	234	1	j	j	PROPN
can-224	234	2	biochem	biochem	PROPN
can-224	234	3	mol	mol	ADP
can-224	234	4	biol	biol	PROPN
can-224	234	5	.	.	PUNCT
can-224	235	1	2007	2007	NUM
can-224	235	2	;	;	PUNCT
can-224	235	3	40	40	NUM
can-224	235	4	(	(	PUNCT
can-224	235	5	5	5	NUM
can-224	235	6	):	):	PUNCT
can-224	235	7	731	731	NUM
can-224	235	8	-	-	SYM
can-224	235	9	739	739	NUM
can-224	235	10	.	.	NOUN
can-224	235	11	20	20	NUM
can-224	235	12	.	.	X
can-224	236	1	sc	sc	PROPN
can-224	236	2	.	.	PROPN
can-224	236	3	yang	yang	PROPN
can-224	236	4	,	,	PUNCT
can-224	236	5	jw	jw	PROPN
can-224	236	6	.	.	PROPN
can-224	236	7	zhu	zhu	PROPN
can-224	236	8	,	,	PUNCT
can-224	237	1	bw	bw	PROPN
can-224	237	2	.	.	PROPN
can-224	237	3	liang	liang	PROPN
can-224	237	4	,	,	PUNCT
can-224	237	5	et	et	PROPN
can-224	237	6	al	al	PROPN
can-224	237	7	.	.	PROPN
can-224	237	8	camptothecin	camptothecin	PROPN
can-224	237	9	solid	solid	ADJ
can-224	237	10	lipid	lipid	NOUN
can-224	237	11	nanoparticles	nanoparticle	NOUN
can-224	238	1	[	[	X
can-224	238	2	j	j	X
can-224	238	3	]	]	X
can-224	238	4	.	.	PUNCT
can-224	239	1	chinese	chinese	ADJ
can-224	239	2	journal	journal	PROPN
can-224	239	3	of	of	ADP
can-224	239	4	pharmacology	pharmacology	NOUN
can-224	239	5	,	,	PUNCT
can-224	239	6	1999,34	1999,34	NUM
can-224	239	7	(	(	PUNCT
can-224	239	8	2	2	NUM
can-224	239	9	):	):	PUNCT
can-224	239	10	146	146	NUM
can-224	239	11	-	-	SYM
can-224	239	12	150	150	NUM
can-224	239	13	.	.	PUNCT
can-224	240	1	21	21	NUM
can-224	240	2	.	.	PUNCT
can-224	241	1	yue	yue	PROPN
can-224	241	2	g	g	PROPN
can-224	241	3	z	z	PROPN
can-224	241	4	,	,	PUNCT
can-224	241	5	qiu	qiu	PROPN
can-224	241	6	q	q	PROPN
can-224	241	7	,	,	PUNCT
can-224	241	8	gao	gao	PROPN
can-224	241	9	b	b	PROPN
can-224	241	10	,	,	PUNCT
can-224	241	11	et	et	NOUN
can-224	241	12	a1	a1	NOUN
can-224	241	13	.	.	PUNCT
can-224	242	1	generation	generation	NOUN
can-224	242	2	of	of	ADP
can-224	242	3	continuous	continuous	ADJ
can-224	242	4	and	and	CCONJ
can-224	242	5	pulsed	pulse	VERB
can-224	242	6	diagnostic	diagnostic	ADJ
can-224	242	7	imaging	imaging	NOUN
can-224	242	8	x	x	NOUN
can-224	242	9	-	-	NOUN
can-224	242	10	ray	ray	NOUN
can-224	242	11	radiation	radiation	NOUN
can-224	242	12	using	use	VERB
can-224	242	13	a	a	DET
can-224	242	14	carbonnanotube	carbonnanotube	NOUN
can-224	242	15	-	-	PUNCT
can-224	242	16	based	base	VERB
can-224	242	17	fi	fi	NOUN
can-224	242	18	eld	eld	NOUN
can-224	242	19	-	-	PUNCT
can-224	242	20	emission	emission	NOUN
can-224	242	21	cathode	cathode	NOUN
can-224	243	1	[	[	X
can-224	243	2	j	j	X
can-224	243	3	]	]	X
can-224	243	4	.	.	PUNCT
can-224	244	1	appl	appl	PROPN
can-224	244	2	phys	phy	NOUN
can-224	244	3	lett	lett	PROPN
can-224	244	4	,	,	PUNCT
can-224	244	5	2002	2002	NUM
can-224	244	6	,	,	PUNCT
can-224	244	7	81	81	NUM
can-224	244	8	:	:	SYM
can-224	244	9	355	355	NUM
can-224	244	10	22	22	NUM
can-224	244	11	.	.	PUNCT
can-224	245	1	dz	dz	PROPN
can-224	245	2	.	.	PUNCT
can-224	246	1	liu	liu	PROPN
can-224	246	2	.	.	PUNCT
can-224	247	1	modern	modern	ADJ
can-224	247	2	ray	ray	NOUN
can-224	247	3	detection	detection	NOUN
can-224	247	4	technology	technology	NOUN
can-224	247	5	.	.	PUNCT
can-224	248	1	beijing	beijing	PROPN
can-224	248	2	:	:	PUNCT
can-224	249	1	china	china	PROPN
can-224	249	2	standard	standard	PROPN
can-224	249	3	press	press	PROPN
can-224	249	4	,	,	PUNCT
can-224	249	5	999.42	999.42	NUM
can-224	249	6	23	23	NUM
can-224	249	7	.	.	PUNCT
can-224	250	1	helga	helga	PROPN
can-224	250	2	e.	e.	PROPN
can-224	250	3	de	de	PROPN
can-224	250	4	vries	vries	PROPN
can-224	250	5	et	et	PROPN
can-224	250	6	al	al	PROPN
can-224	250	7	.	.	PUNCT
can-224	250	8	blood	blood	NOUN
can-224	250	9	-	-	PUNCT
can-224	250	10	brain	brain	NOUN
can-224	250	11	barrier	barrier	NOUN
can-224	250	12	in	in	ADP
can-224	250	13	neuroinf	neuroinf	ADJ
can-224	250	14	lammatorydiseases	lammatorydisease	NOUN
can-224	251	1	[	[	X
can-224	251	2	j	j	X
can-224	251	3	]	]	X
can-224	251	4	.	.	PUNCT
can-224	252	1	pharmacol	pharmacol	PROPN
can-224	252	2	rev	rev	PROPN
can-224	252	3	,	,	PUNCT
can-224	252	4	1997	1997	NUM
can-224	252	5	,	,	PUNCT
can-224	252	6	49	49	NUM
can-224	252	7	:	:	PUNCT
can-224	252	8	143	143	NUM
can-224	252	9	-	-	SYM
can-224	252	10	155	155	NUM
can-224	252	11	24	24	NUM
can-224	252	12	.	.	PUNCT
can-224	253	1	s.	s.	PROPN
can-224	253	2	e.	e.	PROPN
can-224	253	3	gelperina	gelperina	PROPN
can-224	253	4	,	,	PUNCT
can-224	253	5	z.	z.	PROPN
can-224	253	6	smmirnova	smmirnova	PROPN
can-224	253	7	,	,	PUNCT
can-224	253	8	a.s	a.s	PROPN
can-224	253	9	.	.	PROPN
can-224	253	10	khalanskiy	khalanskiy	NOUN
can-224	253	11	,	,	PUNCT
can-224	253	12	in	in	ADV
can-224	253	13	.	.	PUNCT
can-224	254	1	skidan	skidan	PROPN
can-224	254	2	,	,	PUNCT
can-224	254	3	aibobruskin	aibobruskin	PROPN
can-224	254	4	,	,	PUNCT
can-224	254	5	j.	j.	PROPN
can-224	254	6	kreuter	kreuter	PROPN
can-224	254	7	.	.	PUNCT
can-224	255	1	chemotherapy	chemotherapy	NOUN
can-224	255	2	of	of	ADP
can-224	255	3	brain	brain	NOUN
can-224	255	4	tumours	tumour	NOUN
can-224	255	5	using	use	VERB
can-224	255	6	doxoru	doxoru	PROPN
can-224	255	7	bicin	bicin	PROPN
can-224	255	8	bound	bind	VERB
can-224	255	9	to	to	PART
can-224	255	10	polysorbate	polysorbate	VERB
can-224	255	11	80	80	NUM
can-224	255	12	-	-	PUNCT
can-224	255	13	coated	coat	VERB
can-224	255	14	nanoparticles	nanoparticle	NOUN
can-224	255	15	.	.	PUNCT
can-224	256	1	proceedings	proceeding	NOUN
can-224	256	2	of	of	ADP
can-224	256	3	the	the	DET
can-224	256	4	3rd	3rd	ADJ
can-224	256	5	world	world	NOUN
can-224	256	6	meeting	meet	VERB
can-224	256	7	apv	apv	PROPN
can-224	256	8	/	/	SYM
can-224	256	9	apgi	apgi	PROPN
can-224	256	10	,	,	PUNCT
can-224	256	11	berlin	berlin	PROPN
can-224	256	12	,	,	PUNCT
can-224	256	13	2000	2000	NUM
can-224	256	14	,	,	PUNCT
can-224	256	15	3/6th	3/6th	NUM
can-224	256	16	april	april	PROPN
can-224	256	17	2000	2000	NUM
can-224	256	18	,	,	PUNCT
can-224	256	19	441	441	NUM
can-224	256	20	-	-	SYM
can-224	256	21	442	442	NUM
can-224	256	22	25	25	NUM
can-224	256	23	.	.	PUNCT
can-224	257	1	d.	d.	PROPN
can-224	257	2	j.	j.	PROPN
can-224	257	3	selkoe	selkoe	PROPN
can-224	257	4	.	.	PUNCT
can-224	258	1	alzheimer	alzheimer	PROPN
can-224	258	2	's	's	PART
can-224	258	3	disease	disease	NOUN
can-224	258	4	:	:	PUNCT
can-224	258	5	genes	gene	NOUN
can-224	258	6	,	,	PUNCT
can-224	258	7	proteins	protein	NOUN
can-224	258	8	and	and	CCONJ
can-224	258	9	therapy	therapy	NOUN
can-224	258	10	.	.	PUNCT
can-224	259	1	phys	phy	NOUN
can-224	259	2	rev	rev	VERB
can-224	259	3	.	.	PROPN
can-224	259	4	2001	2001	NUM
can-224	259	5	,	,	PUNCT
can-224	259	6	81	81	NUM
can-224	259	7	:	:	PUNCT
can-224	259	8	741	741	NUM
can-224	259	9	-	-	SYM
can-224	259	10	766	766	NUM