id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cet-13799		cet-13799		6	.pdf	application/pdf	3492	135	32	Review Methods A keyword search of the following was carried out on the Scopus and Elsevier databases: Sustainable Pharmaceutical Manufacturing (SPM), process intensification, green metrics, continuous biomanufacturing (CBM), digitalization & I4.0, batch-to-continuous process operation, DT lifecycle, model-assisted design of experiments (DoE), advanced process control, process monitoring & control. DTs show great promise in translating complex data sets into robust process knowledge, enabling consistent product quality with variable process input parameters, transferring nonlinear bioprocesses into dynamic models, and combining advanced process control and green metrics.	cache/cet-13799.pdf	txt/cet-13799.txt