id	sid	tid	token	lemma	pos
cet-1007	1	1	chemical	chemical	NOUN
cet-1007	1	2	engineering	engineering	NOUN
cet-1007	1	3	transactions	transaction	NOUN
cet-1007	1	4	vol	vol	NOUN
cet-1007	1	5	.	.	PROPN
cet-1007	2	1	62	62	NUM
cet-1007	2	2	,	,	PUNCT
cet-1007	2	3	2017	2017	NUM
cet-1007	2	4	a	a	DET
cet-1007	2	5	publication	publication	NOUN
cet-1007	2	6	of	of	ADP
cet-1007	2	7	the	the	DET
cet-1007	2	8	italian	italian	ADJ
cet-1007	2	9	association	association	NOUN
cet-1007	2	10	of	of	ADP
cet-1007	2	11	chemical	chemical	PROPN
cet-1007	2	12	engineering	engineering	NOUN
cet-1007	2	13	online	online	ADV
cet-1007	2	14	at	at	ADP
cet-1007	2	15	www.aidic.it/cet	www.aidic.it/cet	PROPN
cet-1007	2	16	guest	guest	PROPN
cet-1007	2	17	editors	editor	NOUN
cet-1007	2	18	:	:	PUNCT
cet-1007	2	19	fei	fei	PROPN
cet-1007	2	20	song	song	PROPN
cet-1007	2	21	,	,	PUNCT
cet-1007	2	22	haibo	haibo	PROPN
cet-1007	2	23	wang	wang	PROPN
cet-1007	2	24	,	,	PUNCT
cet-1007	2	25	fang	fang	PROPN
cet-1007	2	26	he	he	PRON
cet-1007	2	27	copyright	copyright	NOUN
cet-1007	2	28	©	©	PROPN
cet-1007	2	29	2017	2017	NUM
cet-1007	2	30	,	,	PUNCT
cet-1007	2	31	aidic	aidic	ADJ
cet-1007	2	32	servizi	servizi	PROPN
cet-1007	2	33	s.r.l	s.r.l	PROPN
cet-1007	2	34	.	.	PUNCT
cet-1007	3	1	isbn	isbn	ADJ
cet-1007	3	2	978	978	NUM
cet-1007	3	3	-	-	SYM
cet-1007	3	4	88	88	NUM
cet-1007	3	5	-	-	PUNCT
cet-1007	3	6	9560860	9560860	NUM
cet-1007	3	7	-	-	SYM
cet-1007	3	8	0	0	NUM
cet-1007	3	9	;	;	PUNCT
cet-1007	3	10	issn	issn	PROPN
cet-1007	3	11	2283	2283	NUM
cet-1007	3	12	-	-	SYM
cet-1007	3	13	9216	9216	NUM
cet-1007	3	14	analgesic	analgesic	ADJ
cet-1007	3	15	activity	activity	NOUN
cet-1007	3	16	,	,	PUNCT
cet-1007	3	17	toxicity	toxicity	NOUN
cet-1007	3	18	and	and	CCONJ
cet-1007	3	19	alkaloid	alkaloid	NOUN
cet-1007	3	20	composition	composition	NOUN
cet-1007	3	21	variations	variation	NOUN
cet-1007	3	22	of	of	ADP
cet-1007	3	23	fermented	ferment	VERB
cet-1007	3	24	aconitum	aconitum	ADJ
cet-1007	3	25	carmichaeli	carmichaeli	ADJ
cet-1007	3	26	debx	debx	NOUN
cet-1007	3	27	yi	yi	PROPN
cet-1007	3	28	le	le	PROPN
cet-1007	3	29	,	,	PUNCT
cet-1007	3	30	zaichang	zaichang	PROPN
cet-1007	3	31	yang	yang	PROPN
cet-1007	3	32	*	*	PROPN
cet-1007	3	33	,	,	PUNCT
cet-1007	3	34	chong	chong	PROPN
cet-1007	3	35	qiao	qiao	PROPN
cet-1007	3	36	school	school	PROPN
cet-1007	3	37	of	of	ADP
cet-1007	3	38	pharmaceutical	pharmaceutical	NOUN
cet-1007	3	39	sciences	science	NOUN
cet-1007	3	40	,	,	PUNCT
cet-1007	3	41	guizhou	guizhou	PROPN
cet-1007	3	42	university	university	PROPN
cet-1007	3	43	,	,	PUNCT
cet-1007	3	44	guiyang	guiyang	NOUN
cet-1007	3	45	550025	550025	NUM
cet-1007	3	46	,	,	PUNCT
cet-1007	3	47	china	china	PROPN
cet-1007	3	48	349062458@qq.com	349062458@qq.com	NUM
cet-1007	3	49	aqueous	aqueous	ADJ
cet-1007	3	50	extract	extract	NOUN
cet-1007	3	51	of	of	ADP
cet-1007	3	52	aconitum	aconitum	ADJ
cet-1007	3	53	carmichaeli	carmichaeli	ADJ
cet-1007	3	54	debx	debx	NOUN
cet-1007	3	55	is	be	AUX
cet-1007	3	56	fermented	ferment	VERB
cet-1007	3	57	by	by	ADP
cet-1007	3	58	saccharomyces	saccharomyce	NOUN
cet-1007	3	59	cerevisiae	cerevisiae	NOUN
cet-1007	3	60	where	where	SCONJ
cet-1007	3	61	the	the	DET
cet-1007	3	62	transformations	transformation	NOUN
cet-1007	3	63	in	in	ADP
cet-1007	3	64	alkaloids	alkaloid	NOUN
cet-1007	3	65	are	be	AUX
cet-1007	3	66	analyzed	analyze	VERB
cet-1007	3	67	with	with	ADP
cet-1007	3	68	hplc	hplc	NOUN
cet-1007	3	69	.	.	PUNCT
cet-1007	4	1	in	in	ADP
cet-1007	4	2	the	the	DET
cet-1007	4	3	yeast	yeast	NOUN
cet-1007	4	4	-	-	PUNCT
cet-1007	4	5	fermented	ferment	VERB
cet-1007	4	6	aconitum	aconitum	ADJ
cet-1007	4	7	chloroform	chloroform	NOUN
cet-1007	4	8	extract	extract	NOUN
cet-1007	4	9	,	,	PUNCT
cet-1007	4	10	the	the	DET
cet-1007	4	11	content	content	NOUN
cet-1007	4	12	of	of	ADP
cet-1007	4	13	hypaconitine	hypaconitine	NOUN
cet-1007	4	14	is	be	AUX
cet-1007	4	15	lessened	lessen	VERB
cet-1007	4	16	from	from	ADP
cet-1007	4	17	63.6	63.6	NUM
cet-1007	4	18	%	%	NOUN
cet-1007	4	19	to	to	ADP
cet-1007	4	20	14.8	14.8	NUM
cet-1007	4	21	%	%	NOUN
cet-1007	4	22	;	;	PUNCT
cet-1007	4	23	the	the	DET
cet-1007	4	24	content	content	NOUN
cet-1007	4	25	of	of	ADP
cet-1007	4	26	songorine	songorine	NOUN
cet-1007	4	27	increases	increase	NOUN
cet-1007	4	28	from	from	ADP
cet-1007	4	29	7.5	7.5	NUM
cet-1007	4	30	%	%	NOUN
cet-1007	4	31	to	to	ADP
cet-1007	4	32	34.5	34.5	NUM
cet-1007	4	33	%	%	NOUN
cet-1007	4	34	in	in	ADP
cet-1007	4	35	relation	relation	NOUN
cet-1007	4	36	to	to	ADP
cet-1007	4	37	original	original	ADJ
cet-1007	4	38	aconitum	aconitum	NOUN
cet-1007	4	39	.	.	PUNCT
cet-1007	5	1	in	in	ADP
cet-1007	5	2	tail	tail	NOUN
cet-1007	5	3	clip	clip	NOUN
cet-1007	5	4	test	test	NOUN
cet-1007	5	5	on	on	ADP
cet-1007	5	6	mice	mouse	NOUN
cet-1007	5	7	,	,	PUNCT
cet-1007	5	8	both	both	PRON
cet-1007	5	9	original	original	ADJ
cet-1007	5	10	(	(	PUNCT
cet-1007	5	11	ed50	ed50	PROPN
cet-1007	5	12	,	,	PUNCT
cet-1007	5	13	0.25	0.25	NUM
cet-1007	5	14	±	±	NOUN
cet-1007	5	15	0.04	0.04	NUM
cet-1007	5	16	mg	mg	PROPN
cet-1007	5	17	/	/	SYM
cet-1007	5	18	kg	kg	NOUN
cet-1007	5	19	)	)	PUNCT
cet-1007	5	20	and	and	CCONJ
cet-1007	5	21	yeastfermented	yeastfermente	VERB
cet-1007	5	22	aconitum	aconitum	NOUN
cet-1007	5	23	(	(	PUNCT
cet-1007	5	24	ed50	ed50	PROPN
cet-1007	5	25	,	,	PUNCT
cet-1007	5	26	0.44	0.44	NUM
cet-1007	5	27	±	±	NUM
cet-1007	5	28	0.12	0.12	NUM
cet-1007	5	29	mg	mg	PROPN
cet-1007	5	30	/	/	SYM
cet-1007	5	31	kg	kg	PROPN
cet-1007	5	32	)	)	PUNCT
cet-1007	5	33	showed	show	VERB
cet-1007	5	34	a	a	DET
cet-1007	5	35	potent	potent	ADJ
cet-1007	5	36	analgesic	analgesic	ADJ
cet-1007	5	37	action	action	NOUN
cet-1007	5	38	.	.	PUNCT
cet-1007	6	1	however	however	ADV
cet-1007	6	2	,	,	PUNCT
cet-1007	6	3	the	the	DET
cet-1007	6	4	fermentation	fermentation	NOUN
cet-1007	6	5	process	process	NOUN
cet-1007	6	6	may	may	AUX
cet-1007	6	7	certainly	certainly	ADV
cet-1007	6	8	relieve	relieve	VERB
cet-1007	6	9	the	the	DET
cet-1007	6	10	toxicity	toxicity	NOUN
cet-1007	6	11	of	of	ADP
cet-1007	6	12	aconitum	aconitum	NOUN
cet-1007	6	13	.	.	PUNCT
cet-1007	7	1	the	the	DET
cet-1007	7	2	ld50	ld50	PROPN
cet-1007	7	3	values	value	NOUN
cet-1007	7	4	of	of	ADP
cet-1007	7	5	original	original	ADJ
cet-1007	7	6	and	and	CCONJ
cet-1007	7	7	yeastfermented	yeastfermente	VERB
cet-1007	7	8	aconitum	aconitum	NOUN
cet-1007	7	9	are	be	AUX
cet-1007	7	10	about	about	ADV
cet-1007	7	11	1.44	1.44	NUM
cet-1007	7	12	mg	mg	NUM
cet-1007	7	13	/	/	SYM
cet-1007	7	14	kg	kg	PROPN
cet-1007	7	15	and	and	CCONJ
cet-1007	7	16	13.80	13.80	NUM
cet-1007	7	17	mg	mg	PROPN
cet-1007	7	18	/	/	SYM
cet-1007	7	19	kg	kg	PROPN
cet-1007	7	20	,	,	PUNCT
cet-1007	7	21	respectively	respectively	ADV
cet-1007	7	22	,	,	PUNCT
cet-1007	7	23	but	but	CCONJ
cet-1007	7	24	the	the	DET
cet-1007	7	25	latter	latter	NOUN
cet-1007	7	26	has	have	VERB
cet-1007	7	27	a	a	DET
cet-1007	7	28	greater	great	ADJ
cet-1007	7	29	therapeutic	therapeutic	ADJ
cet-1007	7	30	scope	scope	NOUN
cet-1007	7	31	than	than	ADP
cet-1007	7	32	the	the	DET
cet-1007	7	33	former	former	NOUN
cet-1007	7	34	.	.	PUNCT
cet-1007	8	1	this	this	DET
cet-1007	8	2	discovery	discovery	NOUN
cet-1007	8	3	may	may	AUX
cet-1007	8	4	provide	provide	VERB
cet-1007	8	5	a	a	DET
cet-1007	8	6	way	way	NOUN
cet-1007	8	7	to	to	PART
cet-1007	8	8	develop	develop	VERB
cet-1007	8	9	new	new	ADJ
cet-1007	8	10	analgesics	analgesic	NOUN
cet-1007	8	11	.	.	PUNCT
cet-1007	9	1	1	1	X
cet-1007	9	2	.	.	X
cet-1007	9	3	introduction	introduction	NOUN
cet-1007	9	4	opioids	opioid	NOUN
cet-1007	9	5	and	and	CCONJ
cet-1007	9	6	non	non	ADJ
cet-1007	9	7	-	-	ADJ
cet-1007	9	8	steroidal	steroidal	ADJ
cet-1007	9	9	anti	anti	ADJ
cet-1007	9	10	-	-	ADJ
cet-1007	9	11	inflammatory	inflammatory	ADJ
cet-1007	9	12	drugs	drug	NOUN
cet-1007	9	13	(	(	PUNCT
cet-1007	9	14	nsaids	nsaid	NOUN
cet-1007	9	15	)	)	PUNCT
cet-1007	9	16	are	be	AUX
cet-1007	9	17	the	the	DET
cet-1007	9	18	main	main	ADJ
cet-1007	9	19	pharmaceuticals	pharmaceutical	NOUN
cet-1007	9	20	for	for	ADP
cet-1007	9	21	pain	pain	NOUN
cet-1007	9	22	management	management	NOUN
cet-1007	9	23	,	,	PUNCT
cet-1007	9	24	however	however	ADV
cet-1007	9	25	both	both	PRON
cet-1007	9	26	of	of	ADP
cet-1007	9	27	these	these	DET
cet-1007	9	28	classes	class	NOUN
cet-1007	9	29	suffer	suffer	VERB
cet-1007	9	30	from	from	ADP
cet-1007	9	31	setbacks	setback	NOUN
cet-1007	9	32	in	in	ADP
cet-1007	9	33	clinical	clinical	ADJ
cet-1007	9	34	use	use	NOUN
cet-1007	9	35	.	.	PUNCT
cet-1007	10	1	some	some	DET
cet-1007	10	2	nsaids	nsaid	NOUN
cet-1007	10	3	have	have	VERB
cet-1007	10	4	a	a	DET
cet-1007	10	5	certain	certain	ADJ
cet-1007	10	6	efficacy	efficacy	NOUN
cet-1007	10	7	against	against	ADP
cet-1007	10	8	gastric	gastric	ADJ
cet-1007	10	9	damage	damage	NOUN
cet-1007	10	10	as	as	ADV
cet-1007	10	11	well	well	ADV
cet-1007	10	12	as	as	ADP
cet-1007	10	13	kidney	kidney	NOUN
cet-1007	10	14	and	and	CCONJ
cet-1007	10	15	liver	liver	NOUN
cet-1007	10	16	toxicity	toxicity	NOUN
cet-1007	10	17	,	,	PUNCT
cet-1007	10	18	while	while	SCONJ
cet-1007	10	19	the	the	DET
cet-1007	10	20	opioids	opioid	NOUN
cet-1007	10	21	can	can	AUX
cet-1007	10	22	be	be	AUX
cet-1007	10	23	incident	incident	NOUN
cet-1007	10	24	to	to	PART
cet-1007	10	25	produce	produce	VERB
cet-1007	10	26	addiction	addiction	NOUN
cet-1007	10	27	,	,	PUNCT
cet-1007	10	28	tolerance	tolerance	NOUN
cet-1007	10	29	and	and	CCONJ
cet-1007	10	30	dependence	dependence	NOUN
cet-1007	10	31	on	on	ADP
cet-1007	10	32	human	human	ADJ
cet-1007	10	33	body	body	NOUN
cet-1007	10	34	companied	companie	VERB
cet-1007	10	35	by	by	ADP
cet-1007	10	36	symptoms	symptom	NOUN
cet-1007	10	37	such	such	ADJ
cet-1007	10	38	as	as	ADP
cet-1007	10	39	constipation	constipation	NOUN
cet-1007	10	40	,	,	PUNCT
cet-1007	10	41	nausea	nausea	NOUN
cet-1007	10	42	,	,	PUNCT
cet-1007	10	43	respiratory	respiratory	ADJ
cet-1007	10	44	depression	depression	NOUN
cet-1007	10	45	and	and	CCONJ
cet-1007	10	46	sedation	sedation	NOUN
cet-1007	10	47	.	.	PUNCT
cet-1007	11	1	for	for	ADP
cet-1007	11	2	some	some	DET
cet-1007	11	3	indications	indication	NOUN
cet-1007	11	4	such	such	ADJ
cet-1007	11	5	as	as	ADP
cet-1007	11	6	neuropathic	neuropathic	ADJ
cet-1007	11	7	pain	pain	NOUN
cet-1007	11	8	,	,	PUNCT
cet-1007	11	9	these	these	DET
cet-1007	11	10	classical	classical	ADJ
cet-1007	11	11	medications	medication	NOUN
cet-1007	11	12	appear	appear	VERB
cet-1007	11	13	to	to	PART
cet-1007	11	14	be	be	AUX
cet-1007	11	15	inefficacy	inefficacy	NOUN
cet-1007	11	16	in	in	ADP
cet-1007	11	17	a	a	DET
cet-1007	11	18	substantial	substantial	ADJ
cet-1007	11	19	number	number	NOUN
cet-1007	11	20	of	of	ADP
cet-1007	11	21	patients	patient	NOUN
cet-1007	11	22	.	.	PUNCT
cet-1007	12	1	now	now	ADV
cet-1007	12	2	we	we	PRON
cet-1007	12	3	desperate	desperate	ADJ
cet-1007	12	4	for	for	ADP
cet-1007	12	5	a	a	DET
cet-1007	12	6	class	class	NOUN
cet-1007	12	7	of	of	ADP
cet-1007	12	8	novel	novel	NOUN
cet-1007	12	9	and	and	CCONJ
cet-1007	12	10	safe	safe	ADJ
cet-1007	12	11	analgesics	analgesic	NOUN
cet-1007	12	12	with	with	ADP
cet-1007	12	13	high	high	ADJ
cet-1007	12	14	efficacy	efficacy	NOUN
cet-1007	12	15	against	against	ADP
cet-1007	12	16	algogenesis	algogenesis	NOUN
cet-1007	12	17	(	(	PUNCT
cet-1007	12	18	buschmann	buschmann	PROPN
cet-1007	12	19	et	et	PROPN
cet-1007	12	20	al	al	PROPN
cet-1007	12	21	.	.	PROPN
cet-1007	12	22	,	,	PUNCT
cet-1007	12	23	2004	2004	NUM
cet-1007	12	24	)	)	PUNCT
cet-1007	12	25	aconitum	aconitum	PROPN
cet-1007	12	26	carmichaeli	carmichaeli	ADJ
cet-1007	12	27	debx	debx	NOUN
cet-1007	12	28	,	,	PUNCT
cet-1007	12	29	also	also	ADV
cet-1007	12	30	known	know	VERB
cet-1007	12	31	as	as	ADP
cet-1007	12	32	wu	wu	PROPN
cet-1007	12	33	-	-	PUNCT
cet-1007	12	34	tou	tou	PROPN
cet-1007	12	35	in	in	ADP
cet-1007	12	36	chinese	chinese	PROPN
cet-1007	12	37	,	,	PUNCT
cet-1007	12	38	is	be	AUX
cet-1007	12	39	a	a	DET
cet-1007	12	40	flowering	flower	VERB
cet-1007	12	41	plant	plant	NOUN
cet-1007	12	42	species	specie	NOUN
cet-1007	12	43	of	of	ADP
cet-1007	12	44	the	the	DET
cet-1007	12	45	genus	genus	ADJ
cet-1007	12	46	aconitum	aconitum	NOUN
cet-1007	12	47	in	in	ADP
cet-1007	12	48	the	the	DET
cet-1007	12	49	family	family	NOUN
cet-1007	12	50	ranunculaceae	ranunculaceae	NOUN
cet-1007	12	51	.	.	PUNCT
cet-1007	13	1	the	the	DET
cet-1007	13	2	root	root	NOUN
cet-1007	13	3	of	of	ADP
cet-1007	13	4	wu	wu	PROPN
cet-1007	13	5	-	-	PUNCT
cet-1007	13	6	tou	tou	PROPN
cet-1007	13	7	has	have	AUX
cet-1007	13	8	long	long	ADV
cet-1007	13	9	been	be	AUX
cet-1007	13	10	used	use	VERB
cet-1007	13	11	in	in	ADP
cet-1007	13	12	the	the	DET
cet-1007	13	13	traditional	traditional	ADJ
cet-1007	13	14	chinese	chinese	ADJ
cet-1007	13	15	medicine	medicine	NOUN
cet-1007	13	16	for	for	ADP
cet-1007	13	17	anti	anti	ADJ
cet-1007	13	18	-	-	ADJ
cet-1007	13	19	inflammation	inflammation	ADJ
cet-1007	13	20	and	and	CCONJ
cet-1007	13	21	pain	pain	NOUN
cet-1007	13	22	relief	relief	NOUN
cet-1007	13	23	(	(	PUNCT
cet-1007	13	24	rathbone	rathbone	NOUN
cet-1007	13	25	and	and	CCONJ
cet-1007	13	26	bruce	bruce	PROPN
cet-1007	13	27	,	,	PUNCT
cet-1007	13	28	2002	2002	NUM
cet-1007	13	29	)	)	PUNCT
cet-1007	13	30	.	.	PUNCT
cet-1007	14	1	the	the	DET
cet-1007	14	2	alkaloids	alkaloid	NOUN
cet-1007	14	3	of	of	ADP
cet-1007	14	4	aconitum	aconitum	NOUN
cet-1007	14	5	,	,	PUNCT
cet-1007	14	6	which	which	PRON
cet-1007	14	7	include	include	VERB
cet-1007	14	8	aconitine	aconitine	NOUN
cet-1007	14	9	,	,	PUNCT
cet-1007	14	10	mesaconitine	mesaconitine	NOUN
cet-1007	14	11	,	,	PUNCT
cet-1007	14	12	hypaconitine	hypaconitine	NOUN
cet-1007	14	13	and	and	CCONJ
cet-1007	14	14	so	so	ADV
cet-1007	14	15	on	on	ADV
cet-1007	14	16	,	,	PUNCT
cet-1007	14	17	are	be	AUX
cet-1007	14	18	believed	believe	VERB
cet-1007	14	19	to	to	PART
cet-1007	14	20	possess	possess	VERB
cet-1007	14	21	analgesic	analgesic	ADJ
cet-1007	14	22	activity	activity	NOUN
cet-1007	14	23	,	,	PUNCT
cet-1007	14	24	however	however	ADV
cet-1007	14	25	,	,	PUNCT
cet-1007	14	26	these	these	DET
cet-1007	14	27	c19	c19	NOUN
cet-1007	14	28	diterpenoid	diterpenoid	ADJ
cet-1007	14	29	alkaloids	alkaloid	NOUN
cet-1007	14	30	are	be	AUX
cet-1007	14	31	highly	highly	ADV
cet-1007	14	32	toxic	toxic	ADJ
cet-1007	14	33	.	.	PUNCT
cet-1007	15	1	patients	patient	NOUN
cet-1007	15	2	who	who	PRON
cet-1007	15	3	take	take	VERB
cet-1007	15	4	aconitum	aconitum	NOUN
cet-1007	15	5	may	may	AUX
cet-1007	15	6	die	die	VERB
cet-1007	15	7	from	from	ADP
cet-1007	15	8	ventricular	ventricular	ADJ
cet-1007	15	9	arrhythmias	arrhythmia	NOUN
cet-1007	15	10	,	,	PUNCT
cet-1007	15	11	most	most	ADV
cet-1007	15	12	likely	likely	ADJ
cet-1007	15	13	incident	incident	NOUN
cet-1007	15	14	within	within	ADP
cet-1007	15	15	the	the	DET
cet-1007	15	16	first	first	ADJ
cet-1007	15	17	24	24	NUM
cet-1007	15	18	h.	h.	NOUN
cet-1007	15	19	the	the	DET
cet-1007	15	20	potential	potential	ADJ
cet-1007	15	21	toxicity	toxicity	NOUN
cet-1007	15	22	of	of	ADP
cet-1007	15	23	aconitum	aconitum	PROPN
cet-1007	15	24	limits	limit	VERB
cet-1007	15	25	its	its	PRON
cet-1007	15	26	clinical	clinical	ADJ
cet-1007	15	27	use	use	NOUN
cet-1007	15	28	(	(	PUNCT
cet-1007	15	29	chan	chan	PROPN
cet-1007	15	30	et	et	PROPN
cet-1007	15	31	al	al	PROPN
cet-1007	15	32	.	.	PROPN
cet-1007	15	33	,	,	PUNCT
cet-1007	15	34	1994	1994	NUM
cet-1007	15	35	)	)	PUNCT
cet-1007	15	36	.	.	PUNCT
cet-1007	16	1	isolated	isolate	VERB
cet-1007	16	2	early	early	ADV
cet-1007	16	3	,	,	PUNCT
cet-1007	16	4	many	many	ADJ
cet-1007	16	5	of	of	ADP
cet-1007	16	6	the	the	DET
cet-1007	16	7	pure	pure	ADJ
cet-1007	16	8	compounds	compound	NOUN
cet-1007	16	9	with	with	ADP
cet-1007	16	10	biological	biological	ADJ
cet-1007	16	11	activity	activity	NOUN
cet-1007	16	12	are	be	AUX
cet-1007	16	13	alkaloids	alkaloid	NOUN
cet-1007	16	14	.	.	PUNCT
cet-1007	17	1	as	as	SCONJ
cet-1007	17	2	many	many	ADJ
cet-1007	17	3	valuable	valuable	ADJ
cet-1007	17	4	drugs	drug	NOUN
cet-1007	17	5	are	be	AUX
cet-1007	17	6	derived	derive	VERB
cet-1007	17	7	from	from	ADP
cet-1007	17	8	such	such	ADJ
cet-1007	17	9	natural	natural	ADJ
cet-1007	17	10	compounds	compound	NOUN
cet-1007	17	11	,	,	PUNCT
cet-1007	17	12	it	it	PRON
cet-1007	17	13	is	be	AUX
cet-1007	17	14	a	a	DET
cet-1007	17	15	hotspot	hotspot	NOUN
cet-1007	17	16	that	that	SCONJ
cet-1007	17	17	new	new	ADJ
cet-1007	17	18	or	or	CCONJ
cet-1007	17	19	improved	improved	ADJ
cet-1007	17	20	drugs	drug	NOUN
cet-1007	17	21	may	may	AUX
cet-1007	17	22	be	be	AUX
cet-1007	17	23	synthesized	synthesize	VERB
cet-1007	17	24	by	by	ADP
cet-1007	17	25	the	the	DET
cet-1007	17	26	compounds	compound	NOUN
cet-1007	17	27	or	or	CCONJ
cet-1007	17	28	intermediates	intermediate	NOUN
cet-1007	17	29	transformed	transform	VERB
cet-1007	17	30	from	from	ADP
cet-1007	17	31	alkaloids	alkaloid	NOUN
cet-1007	17	32	.	.	PUNCT
cet-1007	18	1	studies	study	NOUN
cet-1007	18	2	have	have	AUX
cet-1007	18	3	been	be	AUX
cet-1007	18	4	made	make	VERB
cet-1007	18	5	on	on	ADP
cet-1007	18	6	the	the	DET
cet-1007	18	7	structure	structure	NOUN
cet-1007	18	8	modification	modification	NOUN
cet-1007	18	9	of	of	ADP
cet-1007	18	10	microorganisms	microorganism	NOUN
cet-1007	18	11	with	with	ADP
cet-1007	18	12	enormously	enormously	ADV
cet-1007	18	13	diverse	diverse	ADJ
cet-1007	18	14	alkaloids	alkaloid	NOUN
cet-1007	18	15	.	.	PUNCT
cet-1007	18	16	fungi	fungi	PROPN
cet-1007	18	17	,	,	PUNCT
cet-1007	18	18	bacteria	bacteria	NOUN
cet-1007	18	19	,	,	PUNCT
cet-1007	18	20	mammal	mammal	ADJ
cet-1007	18	21	cell	cell	NOUN
cet-1007	18	22	,	,	PUNCT
cet-1007	18	23	and	and	CCONJ
cet-1007	18	24	yeast	yeast	NOUN
cet-1007	18	25	are	be	AUX
cet-1007	18	26	widely	widely	ADV
cet-1007	18	27	used	use	VERB
cet-1007	18	28	in	in	ADP
cet-1007	18	29	biotransformation	biotransformation	NOUN
cet-1007	18	30	.	.	PUNCT
cet-1007	19	1	an	an	DET
cet-1007	19	2	attempt	attempt	NOUN
cet-1007	19	3	is	be	AUX
cet-1007	19	4	to	to	PART
cet-1007	19	5	ferment	ferment	VERB
cet-1007	19	6	the	the	DET
cet-1007	19	7	aconitum	aconitum	ADJ
cet-1007	19	8	root	root	NOUN
cet-1007	19	9	using	use	VERB
cet-1007	19	10	yeast	yeast	NOUN
cet-1007	19	11	for	for	ADP
cet-1007	19	12	several	several	ADJ
cet-1007	19	13	reasons	reason	NOUN
cet-1007	19	14	:	:	PUNCT
cet-1007	19	15	first	first	ADV
cet-1007	19	16	,	,	PUNCT
cet-1007	19	17	yeast	yeast	NOUN
cet-1007	19	18	has	have	AUX
cet-1007	19	19	best	well	ADV
cet-1007	19	20	used	use	VERB
cet-1007	19	21	as	as	ADP
cet-1007	19	22	a	a	DET
cet-1007	19	23	catalyst	catalyst	NOUN
cet-1007	19	24	for	for	ADP
cet-1007	19	25	biotransformation	biotransformation	NOUN
cet-1007	19	26	processes	process	NOUN
cet-1007	19	27	;	;	PUNCT
cet-1007	19	28	secondly	secondly	ADV
cet-1007	19	29	,	,	PUNCT
cet-1007	19	30	yeast	yeast	NOUN
cet-1007	19	31	has	have	VERB
cet-1007	19	32	a	a	DET
cet-1007	19	33	long	long	ADJ
cet-1007	19	34	history	history	NOUN
cet-1007	19	35	of	of	ADP
cet-1007	19	36	application	application	NOUN
cet-1007	19	37	in	in	ADP
cet-1007	19	38	food	food	NOUN
cet-1007	19	39	and	and	CCONJ
cet-1007	19	40	beverage	beverage	NOUN
cet-1007	19	41	production	production	NOUN
cet-1007	19	42	with	with	ADP
cet-1007	19	43	a	a	DET
cet-1007	19	44	proven	prove	VERB
cet-1007	19	45	safety	safety	NOUN
cet-1007	19	46	record	record	NOUN
cet-1007	19	47	for	for	ADP
cet-1007	19	48	human	human	ADJ
cet-1007	19	49	consumption	consumption	NOUN
cet-1007	19	50	.	.	PUNCT
cet-1007	20	1	thirdly	thirdly	ADV
cet-1007	20	2	,	,	PUNCT
cet-1007	20	3	yeast	yeast	NOUN
cet-1007	20	4	is	be	AUX
cet-1007	20	5	inexpensive	inexpensive	ADJ
cet-1007	20	6	and	and	CCONJ
cet-1007	20	7	easy	easy	ADJ
cet-1007	20	8	to	to	PART
cet-1007	20	9	extract	extract	VERB
cet-1007	20	10	(	(	PUNCT
cet-1007	20	11	rathbone	rathbone	NOUN
cet-1007	20	12	and	and	CCONJ
cet-1007	20	13	bruce	bruce	PROPN
cet-1007	20	14	,	,	PUNCT
cet-1007	20	15	2002	2002	NUM
cet-1007	20	16	;	;	PUNCT
cet-1007	20	17	nikolova	nikolova	X
cet-1007	20	18	and	and	CCONJ
cet-1007	20	19	ward	ward	NOUN
cet-1007	20	20	,	,	PUNCT
cet-1007	20	21	1992	1992	NUM
cet-1007	20	22	;	;	PUNCT
cet-1007	20	23	venisetty	venisetty	ADJ
cet-1007	20	24	and	and	CCONJ
cet-1007	20	25	ciddi	ciddi	ADJ
cet-1007	20	26	,	,	PUNCT
cet-1007	20	27	2003	2003	NUM
cet-1007	20	28	;	;	PUNCT
cet-1007	20	29	walker	walker	NOUN
cet-1007	20	30	,	,	PUNCT
cet-1007	20	31	1998	1998	NUM
cet-1007	20	32	)	)	PUNCT
cet-1007	20	33	.	.	PUNCT
cet-1007	21	1	it	it	PRON
cet-1007	21	2	is	be	AUX
cet-1007	21	3	therefore	therefore	ADV
cet-1007	21	4	an	an	DET
cet-1007	21	5	optimal	optimal	ADJ
cet-1007	21	6	microorganism	microorganism	NOUN
cet-1007	21	7	to	to	PART
cet-1007	21	8	be	be	AUX
cet-1007	21	9	used	use	VERB
cet-1007	21	10	for	for	ADP
cet-1007	21	11	biotransformation	biotransformation	NOUN
cet-1007	21	12	of	of	ADP
cet-1007	21	13	aconitum	aconitum	NOUN
cet-1007	21	14	.	.	PUNCT
cet-1007	22	1	in	in	ADP
cet-1007	22	2	the	the	DET
cet-1007	22	3	current	current	ADJ
cet-1007	22	4	study	study	NOUN
cet-1007	22	5	,	,	PUNCT
cet-1007	22	6	we	we	PRON
cet-1007	22	7	are	be	AUX
cet-1007	22	8	interested	interested	ADJ
cet-1007	22	9	in	in	ADP
cet-1007	22	10	what	what	PRON
cet-1007	22	11	happened	happen	VERB
cet-1007	22	12	in	in	ADP
cet-1007	22	13	aconitum	aconitum	NOUN
cet-1007	22	14	during	during	ADP
cet-1007	22	15	the	the	DET
cet-1007	22	16	fermentation	fermentation	NOUN
cet-1007	22	17	process	process	NOUN
cet-1007	22	18	with	with	ADP
cet-1007	22	19	yeast	yeast	NOUN
cet-1007	22	20	.	.	PUNCT
cet-1007	23	1	saccharomyces	saccharomyce	NOUN
cet-1007	23	2	cerevisiae	cerevisiae	NOUN
cet-1007	23	3	is	be	AUX
cet-1007	23	4	used	use	VERB
cet-1007	23	5	to	to	PART
cet-1007	23	6	ferment	ferment	VERB
cet-1007	23	7	the	the	DET
cet-1007	23	8	aconitum	aconitum	ADJ
cet-1007	23	9	root	root	NOUN
cet-1007	23	10	in	in	ADP
cet-1007	23	11	laboratory	laboratory	NOUN
cet-1007	23	12	.	.	PUNCT
cet-1007	24	1	the	the	DET
cet-1007	24	2	contents	content	NOUN
cet-1007	24	3	of	of	ADP
cet-1007	24	4	aconitum	aconitum	NOUN
cet-1007	24	5	before	before	ADV
cet-1007	24	6	and	and	CCONJ
cet-1007	24	7	after	after	ADP
cet-1007	24	8	fermentation	fermentation	NOUN
cet-1007	24	9	are	be	AUX
cet-1007	24	10	analyzed	analyze	VERB
cet-1007	24	11	with	with	ADP
cet-1007	24	12	hplc	hplc	NOUN
cet-1007	24	13	.	.	PUNCT
cet-1007	25	1	the	the	DET
cet-1007	25	2	analgesic	analgesic	ADJ
cet-1007	25	3	activity	activity	NOUN
cet-1007	25	4	and	and	CCONJ
cet-1007	25	5	the	the	DET
cet-1007	25	6	acute	acute	NOUN
cet-1007	25	7	toxicity	toxicity	NOUN
cet-1007	25	8	of	of	ADP
cet-1007	25	9	aconitum	aconitum	NOUN
cet-1007	25	10	before	before	ADV
cet-1007	25	11	and	and	CCONJ
cet-1007	25	12	after	after	ADP
cet-1007	25	13	fermentation	fermentation	NOUN
cet-1007	25	14	are	be	AUX
cet-1007	25	15	also	also	ADV
cet-1007	25	16	evaluated	evaluate	VERB
cet-1007	25	17	in	in	ADP
cet-1007	25	18	the	the	DET
cet-1007	25	19	animal	animal	NOUN
cet-1007	25	20	test	test	NOUN
cet-1007	25	21	models	model	NOUN
cet-1007	25	22	.	.	PUNCT
cet-1007	26	1	doi	doi	NOUN
cet-1007	26	2	:	:	PUNCT
cet-1007	26	3	10.3303	10.3303	NUM
cet-1007	26	4	/	/	SYM
cet-1007	26	5	cet1762209	cet1762209	NOUN
cet-1007	26	6	please	please	INTJ
cet-1007	26	7	cite	cite	VERB
cet-1007	26	8	this	this	DET
cet-1007	26	9	article	article	NOUN
cet-1007	26	10	as	as	ADP
cet-1007	26	11	:	:	PUNCT
cet-1007	26	12	yi	yi	PROPN
cet-1007	26	13	le	le	PROPN
cet-1007	26	14	,	,	PUNCT
cet-1007	26	15	zaichang	zaichang	PROPN
cet-1007	26	16	yang	yang	PROPN
cet-1007	26	17	,	,	PUNCT
cet-1007	26	18	chong	chong	PROPN
cet-1007	26	19	qiao	qiao	PROPN
cet-1007	26	20	,	,	PUNCT
cet-1007	26	21	2017	2017	NUM
cet-1007	26	22	,	,	PUNCT
cet-1007	26	23	analgesic	analgesic	ADJ
cet-1007	26	24	activity	activity	NOUN
cet-1007	26	25	,	,	PUNCT
cet-1007	26	26	toxicity	toxicity	NOUN
cet-1007	26	27	and	and	CCONJ
cet-1007	26	28	alkaloid	alkaloid	NOUN
cet-1007	26	29	composition	composition	NOUN
cet-1007	26	30	variations	variation	NOUN
cet-1007	26	31	of	of	ADP
cet-1007	26	32	fermented	ferment	VERB
cet-1007	26	33	aconitum	aconitum	ADJ
cet-1007	26	34	carmichaeli	carmichaeli	ADJ
cet-1007	26	35	debx	debx	NOUN
cet-1007	26	36	,	,	PUNCT
cet-1007	26	37	chemical	chemical	NOUN
cet-1007	26	38	engineering	engineering	NOUN
cet-1007	26	39	transactions	transaction	NOUN
cet-1007	26	40	,	,	PUNCT
cet-1007	26	41	62	62	NUM
cet-1007	26	42	,	,	PUNCT
cet-1007	26	43	1249	1249	NUM
cet-1007	26	44	-	-	SYM
cet-1007	26	45	1254	1254	NUM
cet-1007	26	46	doi:10.3303	doi:10.3303	NOUN
cet-1007	26	47	/	/	SYM
cet-1007	26	48	cet1762209	cet1762209	NOUN
cet-1007	26	49	1249	1249	NUM
cet-1007	26	50	2	2	NUM
cet-1007	26	51	.	.	PUNCT
cet-1007	27	1	materials	material	NOUN
cet-1007	27	2	and	and	CCONJ
cet-1007	27	3	methodologies	methodology	NOUN
cet-1007	27	4	2.1	2.1	NUM
cet-1007	27	5	plant	plant	NOUN
cet-1007	27	6	material	material	NOUN
cet-1007	27	7	the	the	DET
cet-1007	27	8	fresh	fresh	ADJ
cet-1007	27	9	roots	root	NOUN
cet-1007	27	10	of	of	ADP
cet-1007	27	11	aconitum	aconitum	ADJ
cet-1007	27	12	carmichaeli	carmichaeli	ADJ
cet-1007	27	13	debx	debx	NOUN
cet-1007	27	14	are	be	AUX
cet-1007	27	15	collected	collect	VERB
cet-1007	27	16	in	in	ADP
cet-1007	27	17	guanling	guanling	PROPN
cet-1007	27	18	county	county	NOUN
cet-1007	27	19	,	,	PUNCT
cet-1007	27	20	guizhou	guizhou	PROPN
cet-1007	27	21	province	province	PROPN
cet-1007	27	22	,	,	PUNCT
cet-1007	27	23	china	china	PROPN
cet-1007	27	24	,	,	PUNCT
cet-1007	27	25	and	and	CCONJ
cet-1007	27	26	identified	identify	VERB
cet-1007	27	27	by	by	ADP
cet-1007	27	28	prof	prof	PROPN
cet-1007	27	29	.	.	PUNCT
cet-1007	28	1	deyuan	deyuan	PROPN
cet-1007	28	2	chen	chen	PROPN
cet-1007	28	3	,	,	PUNCT
cet-1007	28	4	department	department	NOUN
cet-1007	28	5	of	of	ADP
cet-1007	28	6	herbal	herbal	ADJ
cet-1007	28	7	sciences	sciences	PROPN
cet-1007	28	8	,	,	PUNCT
cet-1007	28	9	guiyang	guiyang	PROPN
cet-1007	28	10	college	college	PROPN
cet-1007	28	11	of	of	ADP
cet-1007	28	12	traditional	traditional	ADJ
cet-1007	28	13	chinese	chinese	ADJ
cet-1007	28	14	medicine	medicine	NOUN
cet-1007	28	15	,	,	PUNCT
cet-1007	28	16	guiyang	guiyang	PROPN
cet-1007	28	17	,	,	PUNCT
cet-1007	28	18	china	china	PROPN
cet-1007	28	19	.	.	PUNCT
cet-1007	29	1	it	it	PRON
cet-1007	29	2	is	be	AUX
cet-1007	29	3	chopped	chop	VERB
cet-1007	29	4	into	into	ADP
cet-1007	29	5	small	small	ADJ
cet-1007	29	6	pieces	piece	NOUN
cet-1007	29	7	and	and	CCONJ
cet-1007	29	8	air	air	NOUN
cet-1007	29	9	-	-	PUNCT
cet-1007	29	10	dried	dry	VERB
cet-1007	29	11	in	in	ADP
cet-1007	29	12	a	a	DET
cet-1007	29	13	darkened	darken	VERB
cet-1007	29	14	,	,	PUNCT
cet-1007	29	15	ventilated	ventilate	VERB
cet-1007	29	16	cabinet	cabinet	NOUN
cet-1007	29	17	until	until	SCONJ
cet-1007	29	18	the	the	DET
cet-1007	29	19	moisture	moisture	NOUN
cet-1007	29	20	content	content	NOUN
cet-1007	29	21	is	be	AUX
cet-1007	29	22	less	less	ADJ
cet-1007	29	23	than	than	ADP
cet-1007	29	24	5	5	NUM
cet-1007	29	25	%	%	NOUN
cet-1007	29	26	.	.	PUNCT
cet-1007	30	1	a	a	DET
cet-1007	30	2	specimen	speciman	NOUN
cet-1007	30	3	is	be	AUX
cet-1007	30	4	stored	store	VERB
cet-1007	30	5	at	at	ADP
cet-1007	30	6	the	the	DET
cet-1007	30	7	laboratory	laboratory	NOUN
cet-1007	30	8	in	in	ADP
cet-1007	30	9	guizhou	guizhou	PROPN
cet-1007	30	10	university	university	PROPN
cet-1007	30	11	.	.	PUNCT
cet-1007	31	1	2.2	2.2	NUM
cet-1007	31	2	yeast	yeast	NOUN
cet-1007	31	3	culture	culture	NOUN
cet-1007	31	4	the	the	DET
cet-1007	31	5	saccharomyces	saccharomyce	NOUN
cet-1007	31	6	cerevisiae	cerevisiae	NOUN
cet-1007	31	7	strain	strain	NOUN
cet-1007	31	8	(	(	PUNCT
cet-1007	31	9	cicc	cicc	NOUN
cet-1007	31	10	,	,	PUNCT
cet-1007	31	11	1942	1942	NUM
cet-1007	31	12	)	)	PUNCT
cet-1007	31	13	used	use	VERB
cet-1007	31	14	in	in	ADP
cet-1007	31	15	this	this	DET
cet-1007	31	16	study	study	NOUN
cet-1007	31	17	is	be	AUX
cet-1007	31	18	purchased	purchase	VERB
cet-1007	31	19	from	from	ADP
cet-1007	31	20	cicc	cicc	NOUN
cet-1007	31	21	(	(	PUNCT
cet-1007	31	22	chinese	chinese	ADJ
cet-1007	31	23	industry	industry	NOUN
cet-1007	31	24	culture	culture	NOUN
cet-1007	31	25	collection	collection	NOUN
cet-1007	31	26	,	,	PUNCT
cet-1007	31	27	beijing	beijing	PROPN
cet-1007	31	28	,	,	PUNCT
cet-1007	31	29	china	china	PROPN
cet-1007	31	30	)	)	PUNCT
cet-1007	31	31	.	.	PUNCT
cet-1007	32	1	cells	cell	NOUN
cet-1007	32	2	are	be	AUX
cet-1007	32	3	cultured	cultured	ADJ
cet-1007	32	4	aerobically	aerobically	ADV
cet-1007	32	5	in	in	ADP
cet-1007	32	6	yep	yep	PROPN
cet-1007	32	7	(	(	PUNCT
cet-1007	32	8	yeast	yeast	NOUN
cet-1007	32	9	extract	extract	NOUN
cet-1007	32	10	peptone	peptone	NOUN
cet-1007	32	11	)	)	PUNCT
cet-1007	32	12	medium	medium	NOUN
cet-1007	32	13	(	(	PUNCT
cet-1007	32	14	50	50	NUM
cet-1007	32	15	ml	ml	NOUN
cet-1007	32	16	,	,	PUNCT
cet-1007	32	17	ph	ph	ADJ
cet-1007	32	18	5.0	5.0	NUM
cet-1007	32	19	)	)	PUNCT
cet-1007	32	20	containing	contain	VERB
cet-1007	32	21	(	(	PUNCT
cet-1007	32	22	g	g	NOUN
cet-1007	32	23	/	/	SYM
cet-1007	32	24	l):20	l):20	PROPN
cet-1007	32	25	g	g	PROPN
cet-1007	32	26	peptone	peptone	NOUN
cet-1007	32	27	,	,	PUNCT
cet-1007	32	28	10	10	NUM
cet-1007	32	29	g	g	NOUN
cet-1007	32	30	yeast	yeast	NOUN
cet-1007	32	31	extract	extract	NOUN
cet-1007	32	32	,	,	PUNCT
cet-1007	32	33	and	and	CCONJ
cet-1007	32	34	20	20	NUM
cet-1007	32	35	g	g	NOUN
cet-1007	32	36	of	of	ADP
cet-1007	32	37	glucose	glucose	NOUN
cet-1007	32	38	at	at	ADP
cet-1007	32	39	28	28	NUM
cet-1007	32	40	°	°	ADP
cet-1007	32	41	c	c	NOUN
cet-1007	32	42	for	for	ADP
cet-1007	32	43	48h	48h	NOUN
cet-1007	32	44	.	.	PUNCT
cet-1007	33	1	2.3	2.3	NUM
cet-1007	33	2	fermentation	fermentation	NOUN
cet-1007	33	3	the	the	DET
cet-1007	33	4	dry	dry	ADJ
cet-1007	33	5	pieces	piece	NOUN
cet-1007	33	6	of	of	ADP
cet-1007	33	7	aconitum	aconitum	ADJ
cet-1007	33	8	root	root	NOUN
cet-1007	33	9	(	(	PUNCT
cet-1007	33	10	200	200	NUM
cet-1007	33	11	g	g	NOUN
cet-1007	33	12	)	)	PUNCT
cet-1007	33	13	is	be	AUX
cet-1007	33	14	marinated	marinate	VERB
cet-1007	33	15	in	in	ADP
cet-1007	33	16	500	500	NUM
cet-1007	33	17	ml	ml	NOUN
cet-1007	33	18	distilled	distil	VERB
cet-1007	33	19	water	water	NOUN
cet-1007	33	20	for	for	ADP
cet-1007	33	21	30	30	NUM
cet-1007	33	22	min	min	NOUN
cet-1007	33	23	,	,	PUNCT
cet-1007	33	24	then	then	ADV
cet-1007	33	25	boiled	boil	VERB
cet-1007	33	26	it	it	PRON
cet-1007	33	27	for	for	ADP
cet-1007	33	28	1	1	NUM
cet-1007	33	29	h	h	NOUN
cet-1007	33	30	to	to	PART
cet-1007	33	31	obtain	obtain	VERB
cet-1007	33	32	200	200	NUM
cet-1007	33	33	ml	ml	NOUN
cet-1007	33	34	liquid	liquid	ADJ
cet-1007	33	35	extracts	extract	NOUN
cet-1007	33	36	(	(	PUNCT
cet-1007	33	37	ph	ph	NOUN
cet-1007	33	38	7.4	7.4	NUM
cet-1007	33	39	)	)	PUNCT
cet-1007	33	40	which	which	PRON
cet-1007	33	41	is	be	AUX
cet-1007	33	42	poured	pour	VERB
cet-1007	33	43	into	into	ADP
cet-1007	33	44	two	two	NUM
cet-1007	33	45	flasks	flask	NOUN
cet-1007	33	46	(	(	PUNCT
cet-1007	33	47	each	each	DET
cet-1007	33	48	100	100	NUM
cet-1007	33	49	ml	ml	NOUN
cet-1007	33	50	)	)	PUNCT
cet-1007	33	51	,	,	PUNCT
cet-1007	33	52	where	where	SCONJ
cet-1007	33	53	2	2	NUM
cet-1007	33	54	g	g	NOUN
cet-1007	33	55	glucose	glucose	NOUN
cet-1007	33	56	is	be	AUX
cet-1007	33	57	added	add	VERB
cet-1007	33	58	to	to	ADP
cet-1007	33	59	the	the	DET
cet-1007	33	60	liquid	liquid	ADJ
cet-1007	33	61	extract	extract	NOUN
cet-1007	33	62	,	,	PUNCT
cet-1007	33	63	respectively	respectively	ADV
cet-1007	33	64	.	.	PUNCT
cet-1007	34	1	after	after	ADP
cet-1007	34	2	pressure	pressure	NOUN
cet-1007	34	3	sterilization	sterilization	NOUN
cet-1007	34	4	(	(	PUNCT
cet-1007	34	5	0.15	0.15	NUM
cet-1007	34	6	mpa	mpa	NOUN
cet-1007	34	7	for	for	ADP
cet-1007	34	8	20minutes	20minute	NOUN
cet-1007	34	9	)	)	PUNCT
cet-1007	34	10	,	,	PUNCT
cet-1007	34	11	one	one	NUM
cet-1007	34	12	flask	flask	NOUN
cet-1007	34	13	is	be	AUX
cet-1007	34	14	inoculated	inoculate	VERB
cet-1007	34	15	with	with	ADP
cet-1007	34	16	5	5	NUM
cet-1007	34	17	ml	ml	NOUN
cet-1007	34	18	yeast	yeast	NOUN
cet-1007	34	19	culture	culture	NOUN
cet-1007	34	20	(	(	PUNCT
cet-1007	34	21	1.2×108cfu	1.2×108cfu	NUM
cet-1007	34	22	/	/	SYM
cet-1007	34	23	ml	ml	NOUN
cet-1007	34	24	)	)	PUNCT
cet-1007	34	25	,	,	PUNCT
cet-1007	34	26	and	and	CCONJ
cet-1007	34	27	another	another	PRON
cet-1007	34	28	is	be	AUX
cet-1007	34	29	used	use	VERB
cet-1007	34	30	as	as	ADP
cet-1007	34	31	a	a	DET
cet-1007	34	32	negative	negative	ADJ
cet-1007	34	33	control	control	NOUN
cet-1007	34	34	before	before	SCONJ
cet-1007	34	35	it	it	PRON
cet-1007	34	36	is	be	AUX
cet-1007	34	37	fermented	ferment	VERB
cet-1007	34	38	by	by	ADP
cet-1007	34	39	yeast	yeast	NOUN
cet-1007	34	40	.	.	PUNCT
cet-1007	35	1	two	two	NUM
cet-1007	35	2	flasks	flask	NOUN
cet-1007	35	3	are	be	AUX
cet-1007	35	4	placed	place	VERB
cet-1007	35	5	on	on	ADP
cet-1007	35	6	a	a	DET
cet-1007	35	7	rotary	rotary	ADJ
cet-1007	35	8	platform	platform	NOUN
cet-1007	35	9	incubator	incubator	NOUN
cet-1007	35	10	shaker	shaker	NOUN
cet-1007	35	11	at	at	ADP
cet-1007	35	12	200	200	NUM
cet-1007	35	13	rpm	rpm	NOUN
cet-1007	35	14	at	at	ADP
cet-1007	35	15	28	28	NUM
cet-1007	35	16	°	°	ADP
cet-1007	35	17	c	c	NOUN
cet-1007	35	18	for	for	ADP
cet-1007	35	19	4	4	NUM
cet-1007	35	20	days	day	NOUN
cet-1007	35	21	.	.	PUNCT
cet-1007	36	1	during	during	ADP
cet-1007	36	2	the	the	DET
cet-1007	36	3	fermentation	fermentation	NOUN
cet-1007	36	4	,	,	PUNCT
cet-1007	36	5	specimen	speciman	NOUN
cet-1007	36	6	(	(	PUNCT
cet-1007	36	7	1ml	1ml	NOUN
cet-1007	36	8	)	)	PUNCT
cet-1007	36	9	is	be	AUX
cet-1007	36	10	taken	take	VERB
cet-1007	36	11	out	out	ADP
cet-1007	36	12	of	of	ADP
cet-1007	36	13	the	the	DET
cet-1007	36	14	flask	flask	NOUN
cet-1007	36	15	for	for	ADP
cet-1007	36	16	alkaloid	alkaloid	PROPN
cet-1007	36	17	and	and	CCONJ
cet-1007	36	18	cfu	cfu	NOUN
cet-1007	36	19	detection	detection	NOUN
cet-1007	36	20	of	of	ADP
cet-1007	36	21	yeast	yeast	NOUN
cet-1007	36	22	within	within	ADP
cet-1007	36	23	4	4	NUM
cet-1007	36	24	days	day	NOUN
cet-1007	36	25	after	after	ADP
cet-1007	36	26	inoculation	inoculation	NOUN
cet-1007	36	27	with	with	ADP
cet-1007	36	28	yeast	yeast	NOUN
cet-1007	36	29	.	.	PUNCT
cet-1007	37	1	2.4	2.4	NUM
cet-1007	37	2	preparation	preparation	NOUN
cet-1007	37	3	of	of	ADP
cet-1007	37	4	chloroform	chloroform	NOUN
cet-1007	37	5	extract	extract	VERB
cet-1007	37	6	the	the	DET
cet-1007	37	7	above	above	ADJ
cet-1007	37	8	yeast	yeast	NOUN
cet-1007	37	9	-	-	PUNCT
cet-1007	37	10	fermented	ferment	VERB
cet-1007	37	11	and	and	CCONJ
cet-1007	37	12	unfermented	unfermented	ADJ
cet-1007	37	13	(	(	PUNCT
cet-1007	37	14	control	control	NOUN
cet-1007	37	15	)	)	PUNCT
cet-1007	37	16	liquors	liquor	NOUN
cet-1007	37	17	are	be	AUX
cet-1007	37	18	separated	separate	VERB
cet-1007	37	19	by	by	ADP
cet-1007	37	20	filter	filter	NOUN
cet-1007	37	21	paper	paper	NOUN
cet-1007	37	22	to	to	PART
cet-1007	37	23	collect	collect	VERB
cet-1007	37	24	the	the	DET
cet-1007	37	25	liquid	liquid	ADJ
cet-1007	37	26	fraction	fraction	NOUN
cet-1007	37	27	,	,	PUNCT
cet-1007	37	28	extracted	extract	VERB
cet-1007	37	29	with	with	ADP
cet-1007	37	30	chloroform	chloroform	NOUN
cet-1007	37	31	(	(	PUNCT
cet-1007	37	32	100	100	NUM
cet-1007	37	33	ml	ml	NOUN
cet-1007	37	34	)	)	PUNCT
cet-1007	37	35	in	in	ADP
cet-1007	37	36	tap	tap	NOUN
cet-1007	37	37	funnel	funnel	NOUN
cet-1007	37	38	for	for	ADP
cet-1007	37	39	three	three	NUM
cet-1007	37	40	times	time	NOUN
cet-1007	37	41	.	.	PUNCT
cet-1007	38	1	the	the	DET
cet-1007	38	2	extracts	extract	NOUN
cet-1007	38	3	are	be	AUX
cet-1007	38	4	evaporated	evaporate	VERB
cet-1007	38	5	to	to	PART
cet-1007	38	6	dryness	dryness	VERB
cet-1007	38	7	under	under	ADP
cet-1007	38	8	vacuum	vacuum	NOUN
cet-1007	38	9	and	and	CCONJ
cet-1007	38	10	dried	dry	VERB
cet-1007	38	11	in	in	ADP
cet-1007	38	12	vacuum	vacuum	NOUN
cet-1007	38	13	desiccators	desiccator	NOUN
cet-1007	38	14	(	(	PUNCT
cet-1007	38	15	160	160	NUM
cet-1007	38	16	mg	mg	NOUN
cet-1007	38	17	for	for	ADP
cet-1007	38	18	yeast	yeast	NOUN
cet-1007	38	19	-	-	PUNCT
cet-1007	38	20	fermented	ferment	VERB
cet-1007	38	21	specimen	speciman	NOUN
cet-1007	38	22	,	,	PUNCT
cet-1007	38	23	172	172	NUM
cet-1007	38	24	mg	mg	NOUN
cet-1007	38	25	for	for	ADP
cet-1007	38	26	control	control	NOUN
cet-1007	38	27	specimen	speciman	NOUN
cet-1007	38	28	)	)	PUNCT
cet-1007	38	29	.	.	PUNCT
cet-1007	39	1	2.5	2.5	NUM
cet-1007	39	2	hplc	hplc	NOUN
cet-1007	39	3	analysis	analysis	NOUN
cet-1007	39	4	standard	standard	ADJ
cet-1007	39	5	specimens	specimen	NOUN
cet-1007	39	6	of	of	ADP
cet-1007	39	7	mesaconitine	mesaconitine	NOUN
cet-1007	39	8	,	,	PUNCT
cet-1007	39	9	hypaconitine	hypaconitine	NOUN
cet-1007	39	10	and	and	CCONJ
cet-1007	39	11	songorine	songorine	NOUN
cet-1007	39	12	(	(	PUNCT
cet-1007	39	13	figure	figure	NOUN
cet-1007	39	14	1	1	NUM
cet-1007	39	15	)	)	PUNCT
cet-1007	39	16	were	be	AUX
cet-1007	39	17	kindly	kindly	ADV
cet-1007	39	18	provided	provide	VERB
cet-1007	39	19	by	by	ADP
cet-1007	39	20	dr	dr	PROPN
cet-1007	39	21	.	.	PROPN
cet-1007	39	22	pan	pan	PROPN
cet-1007	39	23	weidong	weidong	PROPN
cet-1007	39	24	(	(	PUNCT
cet-1007	39	25	key	key	ADJ
cet-1007	39	26	laboratory	laboratory	NOUN
cet-1007	39	27	of	of	ADP
cet-1007	39	28	chemistry	chemistry	NOUN
cet-1007	39	29	for	for	ADP
cet-1007	39	30	natural	natural	ADJ
cet-1007	39	31	products	product	NOUN
cet-1007	39	32	of	of	ADP
cet-1007	39	33	guizhou	guizhou	PROPN
cet-1007	39	34	province	province	PROPN
cet-1007	39	35	and	and	CCONJ
cet-1007	39	36	chinese	chinese	PROPN
cet-1007	39	37	academy	academy	PROPN
cet-1007	39	38	of	of	ADP
cet-1007	39	39	sciences	sciences	PROPN
cet-1007	39	40	,	,	PUNCT
cet-1007	39	41	guiyang	guiyang	NOUN
cet-1007	39	42	,	,	PUNCT
cet-1007	39	43	china	china	PROPN
cet-1007	39	44	)	)	PUNCT
cet-1007	39	45	.	.	PUNCT
cet-1007	40	1	mesaconitine	mesaconitine	PROPN
cet-1007	40	2	,	,	PUNCT
cet-1007	40	3	hypaconitine	hypaconitine	NOUN
cet-1007	40	4	and	and	CCONJ
cet-1007	40	5	songorine	songorine	NOUN
cet-1007	40	6	are	be	AUX
cet-1007	40	7	accurately	accurately	ADV
cet-1007	40	8	weighed	weigh	VERB
cet-1007	40	9	and	and	CCONJ
cet-1007	40	10	dissolved	dissolve	VERB
cet-1007	40	11	in	in	ADP
cet-1007	40	12	methanol	methanol	NOUN
cet-1007	40	13	to	to	PART
cet-1007	40	14	produce	produce	VERB
cet-1007	40	15	a	a	DET
cet-1007	40	16	stock	stock	NOUN
cet-1007	40	17	standard	standard	ADJ
cet-1007	40	18	solution	solution	NOUN
cet-1007	40	19	at	at	ADP
cet-1007	40	20	a	a	DET
cet-1007	40	21	final	final	ADJ
cet-1007	40	22	concentration	concentration	NOUN
cet-1007	40	23	of	of	ADP
cet-1007	40	24	0.115	0.115	NUM
cet-1007	40	25	mg	mg	PROPN
cet-1007	40	26	/	/	SYM
cet-1007	40	27	ml	ml	PROPN
cet-1007	40	28	,	,	PUNCT
cet-1007	40	29	the	the	DET
cet-1007	40	30	test	test	NOUN
cet-1007	40	31	solution	solution	NOUN
cet-1007	40	32	specimen	speciman	NOUN
cet-1007	40	33	at	at	ADP
cet-1007	40	34	a	a	DET
cet-1007	40	35	final	final	ADJ
cet-1007	40	36	concentration	concentration	NOUN
cet-1007	40	37	of	of	ADP
cet-1007	40	38	0.785	0.785	NUM
cet-1007	40	39	mg	mg	NUM
cet-1007	40	40	/	/	SYM
cet-1007	40	41	ml	ml	NOUN
cet-1007	40	42	.	.	PUNCT
cet-1007	41	1	a	a	DET
cet-1007	41	2	hp1100	hp1100	NOUN
cet-1007	41	3	hplc	hplc	NOUN
cet-1007	41	4	system	system	NOUN
cet-1007	41	5	used	use	VERB
cet-1007	41	6	in	in	ADP
cet-1007	41	7	the	the	DET
cet-1007	41	8	study	study	NOUN
cet-1007	41	9	consisted	consist	VERB
cet-1007	41	10	of	of	ADP
cet-1007	41	11	a	a	DET
cet-1007	41	12	g1315adad	g1315adad	NOUN
cet-1007	41	13	detector	detector	NOUN
cet-1007	41	14	,	,	PUNCT
cet-1007	41	15	a	a	DET
cet-1007	41	16	g1311a	g1311a	X
cet-1007	41	17	quaternary	quaternary	ADJ
cet-1007	41	18	pump	pump	NOUN
cet-1007	41	19	,	,	PUNCT
cet-1007	41	20	a	a	DET
cet-1007	41	21	g1322a	g1322a	PROPN
cet-1007	41	22	vacuum	vacuum	NOUN
cet-1007	41	23	degasser	degasser	PROPN
cet-1007	41	24	and	and	CCONJ
cet-1007	41	25	a	a	DET
cet-1007	41	26	g1367a	g1367a	NOUN
cet-1007	41	27	well	well	ADV
cet-1007	41	28	plate	plate	NOUN
cet-1007	41	29	autosampler	autosampler	NOUN
cet-1007	41	30	.	.	PUNCT
cet-1007	42	1	zorbax	zorbax	PROPN
cet-1007	42	2	c8	c8	PROPN
cet-1007	42	3	reverse	reverse	PROPN
cet-1007	42	4	phase	phase	NOUN
cet-1007	42	5	column	column	NOUN
cet-1007	42	6	(	(	PUNCT
cet-1007	42	7	i	i	NOUN
cet-1007	42	8	d	d	PROPN
cet-1007	42	9	4.6×250	4.6×250	PROPN
cet-1007	42	10	mm	mm	PROPN
cet-1007	42	11	,	,	PUNCT
cet-1007	42	12	particle	particle	NOUN
cet-1007	42	13	size	size	NOUN
cet-1007	42	14	5μm	5μm	NOUN
cet-1007	42	15	)	)	PUNCT
cet-1007	42	16	is	be	AUX
cet-1007	42	17	used	use	VERB
cet-1007	42	18	as	as	ADP
cet-1007	42	19	the	the	DET
cet-1007	42	20	stationary	stationary	ADJ
cet-1007	42	21	phase	phase	NOUN
cet-1007	42	22	.	.	PUNCT
cet-1007	43	1	the	the	DET
cet-1007	43	2	mobile	mobile	ADJ
cet-1007	43	3	phase	phase	NOUN
cet-1007	43	4	consisted	consist	VERB
cet-1007	43	5	of	of	ADP
cet-1007	43	6	glacial	glacial	ADJ
cet-1007	43	7	acetic	acetic	ADJ
cet-1007	43	8	acid	acid	NOUN
cet-1007	43	9	(	(	PUNCT
cet-1007	43	10	0.2	0.2	NUM
cet-1007	43	11	%	%	NOUN
cet-1007	43	12	,	,	PUNCT
cet-1007	43	13	adjusted	adjust	VERB
cet-1007	43	14	to	to	ADP
cet-1007	43	15	ph	ph	NOUN
cet-1007	43	16	5.43	5.43	NUM
cet-1007	43	17	with	with	ADP
cet-1007	43	18	triethylamine	triethylamine	NOUN
cet-1007	43	19	):	):	PUNCT
cet-1007	43	20	methanol	methanol	NOUN
cet-1007	43	21	(	(	PUNCT
cet-1007	43	22	55:45	55:45	NUM
cet-1007	43	23	)	)	PUNCT
cet-1007	43	24	at	at	ADP
cet-1007	43	25	a	a	DET
cet-1007	43	26	flow	flow	NOUN
cet-1007	43	27	rate	rate	NOUN
cet-1007	43	28	of	of	ADP
cet-1007	43	29	0.8	0.8	NUM
cet-1007	43	30	ml	ml	NOUN
cet-1007	43	31	/	/	SYM
cet-1007	43	32	min	min	NOUN
cet-1007	43	33	.	.	PROPN
cet-1007	43	34	detection	detection	NOUN
cet-1007	43	35	is	be	AUX
cet-1007	43	36	carried	carry	VERB
cet-1007	43	37	out	out	ADP
cet-1007	43	38	at	at	ADP
cet-1007	43	39	231	231	NUM
cet-1007	43	40	nm	nm	NOUN
cet-1007	43	41	at	at	ADP
cet-1007	43	42	25	25	NUM
cet-1007	43	43	°	°	NOUN
cet-1007	43	44	c	c	NOUN
cet-1007	43	45	with	with	ADP
cet-1007	43	46	injection	injection	NOUN
cet-1007	43	47	volume	volume	NOUN
cet-1007	43	48	of3	of3	NUM
cet-1007	43	49	μl	μl	ADV
cet-1007	43	50	for	for	ADP
cet-1007	43	51	all	all	DET
cet-1007	43	52	hplc	hplc	NOUN
cet-1007	43	53	flows	flow	NOUN
cet-1007	43	54	.	.	PUNCT
cet-1007	44	1	mesaconitine	mesaconitine	PROPN
cet-1007	44	2	songorine	songorine	PROPN
cet-1007	44	3	hypaconitine	hypaconitine	NOUN
cet-1007	44	4	figure	figure	NOUN
cet-1007	44	5	1	1	NUM
cet-1007	44	6	:	:	PUNCT
cet-1007	44	7	structures	structure	NOUN
cet-1007	44	8	of	of	ADP
cet-1007	44	9	mesaconitine	mesaconitine	NOUN
cet-1007	44	10	,	,	PUNCT
cet-1007	44	11	songorine	songorine	NOUN
cet-1007	44	12	and	and	CCONJ
cet-1007	44	13	hypaconitine	hypaconitine	VERB
cet-1007	44	14	2.6	2.6	NUM
cet-1007	44	15	animals	animal	NOUN
cet-1007	44	16	for	for	ADP
cet-1007	44	17	tail	tail	NOUN
cet-1007	44	18	clip	clip	NOUN
cet-1007	44	19	test	test	NOUN
cet-1007	44	20	and	and	CCONJ
cet-1007	44	21	determination	determination	NOUN
cet-1007	44	22	of	of	ADP
cet-1007	44	23	median	median	ADJ
cet-1007	44	24	lethal	lethal	ADJ
cet-1007	44	25	dose	dose	NOUN
cet-1007	44	26	(	(	PUNCT
cet-1007	44	27	ld50	ld50	PROPN
cet-1007	44	28	)	)	PUNCT
cet-1007	44	29	the	the	PRON
cet-1007	44	30	in	in	ADP
cet-1007	44	31	vivo	vivo	ADJ
cet-1007	44	32	experiments	experiment	NOUN
cet-1007	44	33	are	be	AUX
cet-1007	44	34	conducted	conduct	VERB
cet-1007	44	35	using	use	VERB
cet-1007	44	36	male	male	ADJ
cet-1007	44	37	kunming	kunme	VERB
cet-1007	44	38	mice	mouse	NOUN
cet-1007	44	39	(	(	PUNCT
cet-1007	44	40	20	20	NUM
cet-1007	44	41	-	-	SYM
cet-1007	44	42	22	22	NUM
cet-1007	44	43	g	g	NOUN
cet-1007	44	44	)	)	PUNCT
cet-1007	44	45	purchased	purchase	VERB
cet-1007	44	46	from	from	ADP
cet-1007	44	47	animal	animal	NOUN
cet-1007	44	48	center	center	NOUN
cet-1007	44	49	of	of	ADP
cet-1007	44	50	guiyang	guiyang	PROPN
cet-1007	44	51	medical	medical	PROPN
cet-1007	44	52	college	college	PROPN
cet-1007	44	53	,	,	PUNCT
cet-1007	44	54	guiyang	guiyang	PROPN
cet-1007	44	55	,	,	PUNCT
cet-1007	44	56	china	china	PROPN
cet-1007	44	57	,	,	PUNCT
cet-1007	44	58	in	in	ADP
cet-1007	44	59	an	an	DET
cet-1007	44	60	animal	animal	NOUN
cet-1007	44	61	room	room	NOUN
cet-1007	44	62	at	at	ADP
cet-1007	44	63	20±2	20±2	PROPN
cet-1007	44	64	°	°	ADP
cet-1007	44	65	c	c	PROPN
cet-1007	44	66	with	with	ADP
cet-1007	44	67	a	a	DET
cet-1007	44	68	12h	12h	NUM
cet-1007	44	69	light	light	ADJ
cet-1007	44	70	/	/	SYM
cet-1007	44	71	dark	dark	ADJ
cet-1007	44	72	cycle	cycle	NOUN
cet-1007	44	73	,	,	PUNCT
cet-1007	44	74	where	where	SCONJ
cet-1007	44	75	food	food	NOUN
cet-1007	44	76	and	and	CCONJ
cet-1007	44	77	tap	tap	NOUN
cet-1007	44	78	water	water	NOUN
cet-1007	44	79	are	be	AUX
cet-1007	44	80	supplied	supply	VERB
cet-1007	44	81	.	.	PUNCT
cet-1007	45	1	all	all	DET
cet-1007	45	2	experiments	experiment	NOUN
cet-1007	45	3	are	be	AUX
cet-1007	45	4	done	do	VERB
cet-1007	45	5	in	in	ADP
cet-1007	45	6	compliance	compliance	NOUN
cet-1007	45	7	with	with	ADP
cet-1007	45	8	the	the	DET
cet-1007	45	9	internationally	internationally	ADV
cet-1007	45	10	accepted	accept	VERB
cet-1007	45	11	standards	standard	NOUN
cet-1007	45	12	for	for	ADP
cet-1007	45	13	animals	animal	NOUN
cet-1007	45	14	and	and	CCONJ
cet-1007	45	15	have	have	AUX
cet-1007	45	16	been	be	AUX
cet-1007	45	17	approved	approve	VERB
cet-1007	45	18	by	by	ADP
cet-1007	45	19	the	the	DET
cet-1007	45	20	guizhou	guizhou	PROPN
cet-1007	45	21	university	university	NOUN
cet-1007	45	22	.	.	PUNCT
cet-1007	46	1	2.7	2.7	NUM
cet-1007	46	2	tail	tail	NOUN
cet-1007	46	3	clip	clip	NOUN
cet-1007	46	4	test	test	NOUN
cet-1007	46	5	in	in	ADP
cet-1007	46	6	mice	mouse	NOUN
cet-1007	46	7	this	this	DET
cet-1007	46	8	analgesic	analgesic	ADJ
cet-1007	46	9	test	test	NOUN
cet-1007	46	10	bases	basis	NOUN
cet-1007	46	11	on	on	ADP
cet-1007	46	12	a	a	DET
cet-1007	46	13	modified	modify	VERB
cet-1007	46	14	method	method	NOUN
cet-1007	46	15	as	as	SCONJ
cet-1007	46	16	proposed	propose	VERB
cet-1007	46	17	by	by	ADP
cet-1007	46	18	bianchi	bianchi	NOUN
cet-1007	46	19	and	and	CCONJ
cet-1007	46	20	franceschini	franceschini	PROPN
cet-1007	46	21	(	(	PUNCT
cet-1007	46	22	bianchi	bianchi	NOUN
cet-1007	46	23	and	and	CCONJ
cet-1007	46	24	franceschini	franceschini	NOUN
cet-1007	46	25	,	,	PUNCT
cet-1007	46	26	1954	1954	NUM
cet-1007	46	27	)	)	PUNCT
cet-1007	46	28	.	.	PUNCT
cet-1007	47	1	the	the	DET
cet-1007	47	2	chloroform	chloroform	NOUN
cet-1007	47	3	extract	extract	NOUN
cet-1007	47	4	of	of	ADP
cet-1007	47	5	aconitum	aconitum	PROPN
cet-1007	47	6	(	(	PUNCT
cet-1007	47	7	cea	cea	PROPN
cet-1007	47	8	)	)	PUNCT
cet-1007	47	9	and	and	CCONJ
cet-1007	47	10	chloroform	chloroform	NOUN
cet-1007	47	11	extract	extract	NOUN
cet-1007	47	12	of	of	ADP
cet-1007	47	13	yeast	yeast	NOUN
cet-1007	47	14	-	-	PUNCT
cet-1007	47	15	fermented	ferment	VERB
cet-1007	47	16	1250	1250	NUM
cet-1007	47	17	aconitum	aconitum	NOUN
cet-1007	47	18	(	(	PUNCT
cet-1007	47	19	ceyfa	ceyfa	PROPN
cet-1007	47	20	)	)	PUNCT
cet-1007	47	21	are	be	AUX
cet-1007	47	22	dissolved	dissolve	VERB
cet-1007	47	23	in	in	ADP
cet-1007	47	24	physiological	physiological	ADJ
cet-1007	47	25	saline	saline	NOUN
cet-1007	47	26	to	to	PART
cet-1007	47	27	obtain	obtain	VERB
cet-1007	47	28	the	the	DET
cet-1007	47	29	stock	stock	NOUN
cet-1007	47	30	solution	solution	NOUN
cet-1007	47	31	of	of	ADP
cet-1007	47	32	1	1	NUM
cet-1007	47	33	mg	mg	NUM
cet-1007	47	34	/	/	SYM
cet-1007	47	35	ml	ml	NOUN
cet-1007	47	36	,	,	PUNCT
cet-1007	47	37	sterilized	sterilize	VERB
cet-1007	47	38	by	by	ADP
cet-1007	47	39	filtration	filtration	NOUN
cet-1007	47	40	through	through	ADP
cet-1007	47	41	a	a	DET
cet-1007	47	42	0.45μm	0.45μm	NUM
cet-1007	47	43	filter	filter	NOUN
cet-1007	47	44	and	and	CCONJ
cet-1007	47	45	further	far	ADV
cet-1007	47	46	diluted	dilute	VERB
cet-1007	47	47	in	in	ADP
cet-1007	47	48	the	the	DET
cet-1007	47	49	experiments	experiment	NOUN
cet-1007	47	50	.	.	PUNCT
cet-1007	48	1	mice	mouse	NOUN
cet-1007	48	2	(	(	PUNCT
cet-1007	48	3	n	n	NOUN
cet-1007	48	4	=	=	NOUN
cet-1007	48	5	10	10	NUM
cet-1007	48	6	)	)	PUNCT
cet-1007	48	7	is	be	AUX
cet-1007	48	8	injected	inject	VERB
cet-1007	48	9	intraperitoneally	intraperitoneally	ADV
cet-1007	48	10	with	with	ADP
cet-1007	48	11	saline	saline	ADJ
cet-1007	48	12	(	(	PUNCT
cet-1007	48	13	negative	negative	ADJ
cet-1007	48	14	control	control	NOUN
cet-1007	48	15	)	)	PUNCT
cet-1007	48	16	,	,	PUNCT
cet-1007	48	17	and	and	CCONJ
cet-1007	48	18	graded	grade	VERB
cet-1007	48	19	doses	dose	NOUN
cet-1007	48	20	(	(	PUNCT
cet-1007	48	21	0.10	0.10	NUM
cet-1007	48	22	,	,	PUNCT
cet-1007	48	23	0.17	0.17	NUM
cet-1007	48	24	,	,	PUNCT
cet-1007	48	25	0.30	0.30	NUM
cet-1007	48	26	,	,	PUNCT
cet-1007	48	27	0.50	0.50	NUM
cet-1007	48	28	or	or	CCONJ
cet-1007	48	29	0.80	0.80	NUM
cet-1007	48	30	mg	mg	PROPN
cet-1007	48	31	/	/	SYM
cet-1007	48	32	kg	kg	NOUN
cet-1007	48	33	)	)	PUNCT
cet-1007	48	34	of	of	ADP
cet-1007	48	35	cea	cea	PROPN
cet-1007	48	36	and	and	CCONJ
cet-1007	48	37	ceyfa	ceyfa	PROPN
cet-1007	48	38	or	or	CCONJ
cet-1007	48	39	morphine	morphine	NOUN
cet-1007	48	40	sulfate	sulfate	NOUN
cet-1007	48	41	(	(	PUNCT
cet-1007	48	42	10mg	10mg	NOUN
cet-1007	48	43	/	/	SYM
cet-1007	48	44	kg	kg	PROPN
cet-1007	48	45	,	,	PUNCT
cet-1007	48	46	reference	reference	NOUN
cet-1007	48	47	drug	drug	NOUN
cet-1007	48	48	)	)	PUNCT
cet-1007	48	49	.	.	PUNCT
cet-1007	49	1	an	an	DET
cet-1007	49	2	artery	artery	NOUN
cet-1007	49	3	clip	clip	NOUN
cet-1007	49	4	is	be	AUX
cet-1007	49	5	applied	apply	VERB
cet-1007	49	6	to	to	ADP
cet-1007	49	7	the	the	DET
cet-1007	49	8	root	root	NOUN
cet-1007	49	9	of	of	ADP
cet-1007	49	10	the	the	DET
cet-1007	49	11	tail	tail	NOUN
cet-1007	49	12	(	(	PUNCT
cet-1007	49	13	approximately	approximately	ADV
cet-1007	49	14	1	1	NUM
cet-1007	49	15	cm	cm	NOUN
cet-1007	49	16	from	from	ADP
cet-1007	49	17	the	the	DET
cet-1007	49	18	body	body	NOUN
cet-1007	49	19	)	)	PUNCT
cet-1007	49	20	to	to	PART
cet-1007	49	21	induce	induce	VERB
cet-1007	49	22	pain	pain	NOUN
cet-1007	49	23	.	.	PUNCT
cet-1007	50	1	the	the	DET
cet-1007	50	2	animal	animal	NOUN
cet-1007	50	3	quickly	quickly	ADV
cet-1007	50	4	responds	respond	VERB
cet-1007	50	5	to	to	ADP
cet-1007	50	6	the	the	DET
cet-1007	50	7	noxious	noxious	ADJ
cet-1007	50	8	stimuli	stimulus	NOUN
cet-1007	50	9	by	by	ADP
cet-1007	50	10	biting	bite	VERB
cet-1007	50	11	the	the	DET
cet-1007	50	12	clip	clip	NOUN
cet-1007	50	13	or	or	CCONJ
cet-1007	50	14	the	the	DET
cet-1007	50	15	tail	tail	NOUN
cet-1007	50	16	near	near	ADP
cet-1007	50	17	the	the	DET
cet-1007	50	18	location	location	NOUN
cet-1007	50	19	of	of	ADP
cet-1007	50	20	the	the	DET
cet-1007	50	21	clip	clip	NOUN
cet-1007	50	22	.	.	PUNCT
cet-1007	51	1	the	the	DET
cet-1007	51	2	time	time	NOUN
cet-1007	51	3	between	between	ADP
cet-1007	51	4	stimulation	stimulation	NOUN
cet-1007	51	5	onset	onset	NOUN
cet-1007	51	6	and	and	CCONJ
cet-1007	51	7	response	response	NOUN
cet-1007	51	8	is	be	AUX
cet-1007	51	9	measured	measure	VERB
cet-1007	51	10	by	by	ADP
cet-1007	51	11	a	a	DET
cet-1007	51	12	stopwatch	stopwatch	NOUN
cet-1007	51	13	.	.	PUNCT
cet-1007	52	1	the	the	DET
cet-1007	52	2	presence	presence	NOUN
cet-1007	52	3	or	or	CCONJ
cet-1007	52	4	absence	absence	NOUN
cet-1007	52	5	of	of	ADP
cet-1007	52	6	analgesia	analgesia	NOUN
cet-1007	52	7	is	be	AUX
cet-1007	52	8	determined	determine	VERB
cet-1007	52	9	at	at	ADP
cet-1007	52	10	15	15	NUM
cet-1007	52	11	,	,	PUNCT
cet-1007	52	12	30	30	NUM
cet-1007	52	13	,	,	PUNCT
cet-1007	52	14	45	45	NUM
cet-1007	52	15	and	and	CCONJ
cet-1007	52	16	60	60	NUM
cet-1007	52	17	min	min	NOUN
cet-1007	52	18	after	after	ADP
cet-1007	52	19	i.p	i.p	PROPN
cet-1007	52	20	.	.	PROPN
cet-1007	52	21	administration	administration	NOUN
cet-1007	52	22	of	of	ADP
cet-1007	52	23	the	the	DET
cet-1007	52	24	tested	test	VERB
cet-1007	52	25	extract	extract	NOUN
cet-1007	52	26	,	,	PUNCT
cet-1007	52	27	respectively	respectively	ADV
cet-1007	52	28	,	,	PUNCT
cet-1007	52	29	with	with	SCONJ
cet-1007	52	30	artery	artery	NOUN
cet-1007	52	31	clip	clip	NOUN
cet-1007	52	32	applied	apply	VERB
cet-1007	52	33	for	for	ADP
cet-1007	52	34	30	30	NUM
cet-1007	52	35	sec	sec	PROPN
cet-1007	52	36	.	.	PUNCT
cet-1007	53	1	the	the	DET
cet-1007	53	2	results	result	NOUN
cet-1007	53	3	are	be	AUX
cet-1007	53	4	expressed	express	VERB
cet-1007	53	5	as	as	ADP
cet-1007	53	6	the	the	DET
cet-1007	53	7	percentage	percentage	NOUN
cet-1007	53	8	of	of	ADP
cet-1007	53	9	mice	mouse	NOUN
cet-1007	53	10	showing	show	VERB
cet-1007	53	11	analgesia	analgesia	NOUN
cet-1007	53	12	-	-	PUNCT
cet-1007	53	13	insensitivity	insensitivity	NOUN
cet-1007	53	14	to	to	ADP
cet-1007	53	15	the	the	DET
cet-1007	53	16	noxious	noxious	ADJ
cet-1007	53	17	stimulus	stimulus	NOUN
cet-1007	53	18	-	-	PUNCT
cet-1007	53	19	after	after	ADP
cet-1007	53	20	treatment	treatment	NOUN
cet-1007	53	21	.	.	PUNCT
cet-1007	54	1	2.8	2.8	NUM
cet-1007	54	2	determination	determination	NOUN
cet-1007	54	3	of	of	ADP
cet-1007	54	4	median	median	ADJ
cet-1007	54	5	lethal	lethal	ADJ
cet-1007	54	6	dose	dose	NOUN
cet-1007	54	7	(	(	PUNCT
cet-1007	54	8	ld50	ld50	PROPN
cet-1007	54	9	)	)	PUNCT
cet-1007	54	10	the	the	DET
cet-1007	54	11	preliminary	preliminary	ADJ
cet-1007	54	12	tests	test	NOUN
cet-1007	54	13	indicate	indicate	VERB
cet-1007	54	14	that	that	SCONJ
cet-1007	54	15	the	the	DET
cet-1007	54	16	cea	cea	PROPN
cet-1007	54	17	shows	show	VERB
cet-1007	54	18	far	far	ADV
cet-1007	54	19	more	more	ADV
cet-1007	54	20	toxic	toxic	ADJ
cet-1007	54	21	than	than	ADP
cet-1007	54	22	the	the	DET
cet-1007	54	23	ceyfa	ceyfa	NOUN
cet-1007	54	24	.	.	PUNCT
cet-1007	55	1	in	in	ADP
cet-1007	55	2	formal	formal	ADJ
cet-1007	55	3	test	test	NOUN
cet-1007	55	4	the	the	DET
cet-1007	55	5	doses	dose	NOUN
cet-1007	55	6	and	and	CCONJ
cet-1007	55	7	the	the	DET
cet-1007	55	8	intervals	interval	NOUN
cet-1007	55	9	between	between	ADP
cet-1007	55	10	the	the	DET
cet-1007	55	11	cea	cea	PROPN
cet-1007	55	12	and	and	CCONJ
cet-1007	55	13	ceyfa	ceyfa	PROPN
cet-1007	55	14	are	be	AUX
cet-1007	55	15	different	different	ADJ
cet-1007	55	16	.	.	PUNCT
cet-1007	56	1	for	for	ADP
cet-1007	56	2	each	each	DET
cet-1007	56	3	extract	extract	NOUN
cet-1007	56	4	,	,	PUNCT
cet-1007	56	5	mice	mouse	NOUN
cet-1007	56	6	are	be	AUX
cet-1007	56	7	divided	divide	VERB
cet-1007	56	8	into	into	ADP
cet-1007	56	9	5	5	NUM
cet-1007	56	10	groups	group	NOUN
cet-1007	56	11	of	of	ADP
cet-1007	56	12	10	10	NUM
cet-1007	56	13	each	each	PRON
cet-1007	56	14	.	.	PUNCT
cet-1007	57	1	the	the	DET
cet-1007	57	2	cea	cea	PROPN
cet-1007	57	3	solution	solution	NOUN
cet-1007	57	4	is	be	AUX
cet-1007	57	5	intraperitoneally	intraperitoneally	ADV
cet-1007	57	6	administered	administer	VERB
cet-1007	57	7	at	at	ADP
cet-1007	57	8	dose	dose	NOUN
cet-1007	57	9	of	of	ADP
cet-1007	57	10	0.8	0.8	NUM
cet-1007	57	11	,	,	PUNCT
cet-1007	57	12	1.2	1.2	NUM
cet-1007	57	13	,	,	PUNCT
cet-1007	57	14	1.8	1.8	NUM
cet-1007	57	15	,	,	PUNCT
cet-1007	57	16	2.7	2.7	NUM
cet-1007	57	17	and	and	CCONJ
cet-1007	57	18	4.1	4.1	NUM
cet-1007	57	19	mg	mg	PROPN
cet-1007	57	20	/	/	SYM
cet-1007	57	21	kg	kg	PROPN
cet-1007	57	22	body	body	NOUN
cet-1007	57	23	weight	weight	NOUN
cet-1007	57	24	.	.	PUNCT
cet-1007	58	1	the	the	DET
cet-1007	58	2	ceyfa	ceyfa	PROPN
cet-1007	58	3	solution	solution	NOUN
cet-1007	58	4	is	be	AUX
cet-1007	58	5	also	also	ADV
cet-1007	58	6	intraperitoneally	intraperitoneally	ADV
cet-1007	58	7	administered	administer	VERB
cet-1007	58	8	at	at	ADP
cet-1007	58	9	dose	dose	NOUN
cet-1007	58	10	of	of	ADP
cet-1007	58	11	4.5	4.5	NUM
cet-1007	58	12	,	,	PUNCT
cet-1007	58	13	7.0	7.0	NUM
cet-1007	58	14	,	,	PUNCT
cet-1007	58	15	12.0	12.0	NUM
cet-1007	58	16	,	,	PUNCT
cet-1007	58	17	20.0	20.0	NUM
cet-1007	58	18	and	and	CCONJ
cet-1007	58	19	34.0	34.0	NUM
cet-1007	58	20	mg	mg	PROPN
cet-1007	58	21	/	/	SYM
cet-1007	58	22	kg	kg	PROPN
cet-1007	58	23	body	body	NOUN
cet-1007	58	24	weight	weight	NOUN
cet-1007	58	25	.	.	PUNCT
cet-1007	59	1	death	death	NOUN
cet-1007	59	2	is	be	AUX
cet-1007	59	3	monitored	monitor	VERB
cet-1007	59	4	over	over	ADP
cet-1007	59	5	a	a	DET
cet-1007	59	6	period	period	NOUN
cet-1007	59	7	of	of	ADP
cet-1007	59	8	24h	24h	NOUN
cet-1007	59	9	.	.	PUNCT
cet-1007	60	1	ld50	ld50	PROPN
cet-1007	60	2	is	be	AUX
cet-1007	60	3	then	then	ADV
cet-1007	60	4	calculated	calculate	VERB
cet-1007	60	5	with	with	ADP
cet-1007	60	6	trimmed	trim	VERB
cet-1007	60	7	spearman	spearman	NOUN
cet-1007	60	8	-	-	PUNCT
cet-1007	60	9	karber	karber	PROPN
cet-1007	60	10	method	method	NOUN
cet-1007	60	11	(	(	PUNCT
cet-1007	60	12	hamilton	hamilton	PROPN
cet-1007	60	13	et	et	PROPN
cet-1007	60	14	al	al	PROPN
cet-1007	60	15	.	.	PROPN
cet-1007	60	16	,	,	PUNCT
cet-1007	60	17	1977	1977	NUM
cet-1007	60	18	)	)	PUNCT
cet-1007	60	19	.	.	PUNCT
cet-1007	61	1	3	3	X
cet-1007	61	2	.	.	NOUN
cet-1007	61	3	results	result	NOUN
cet-1007	61	4	and	and	CCONJ
cet-1007	61	5	discussion	discussion	NOUN
cet-1007	61	6	during	during	ADP
cet-1007	61	7	the	the	DET
cet-1007	61	8	periods	period	NOUN
cet-1007	61	9	of	of	ADP
cet-1007	61	10	fermentation	fermentation	NOUN
cet-1007	61	11	,	,	PUNCT
cet-1007	61	12	tlc	tlc	NOUN
cet-1007	61	13	is	be	AUX
cet-1007	61	14	used	use	VERB
cet-1007	61	15	to	to	PART
cet-1007	61	16	detect	detect	VERB
cet-1007	61	17	the	the	DET
cet-1007	61	18	alkaloids	alkaloid	NOUN
cet-1007	61	19	in	in	ADP
cet-1007	61	20	the	the	DET
cet-1007	61	21	liquid	liquid	ADJ
cet-1007	61	22	extract	extract	NOUN
cet-1007	61	23	of	of	ADP
cet-1007	61	24	aconitum	aconitum	ADJ
cet-1007	61	25	root	root	NOUN
cet-1007	61	26	for	for	ADP
cet-1007	61	27	variants	variant	NOUN
cet-1007	61	28	.	.	PUNCT
cet-1007	62	1	the	the	DET
cet-1007	62	2	results	result	NOUN
cet-1007	62	3	show	show	VERB
cet-1007	62	4	that	that	SCONJ
cet-1007	62	5	the	the	DET
cet-1007	62	6	content	content	NOUN
cet-1007	62	7	of	of	ADP
cet-1007	62	8	alkaloids	alkaloid	NOUN
cet-1007	62	9	in	in	ADP
cet-1007	62	10	the	the	DET
cet-1007	62	11	liquid	liquid	ADJ
cet-1007	62	12	extract	extract	NOUN
cet-1007	62	13	of	of	ADP
cet-1007	62	14	aconitum	aconitum	ADJ
cet-1007	62	15	root	root	NOUN
cet-1007	62	16	has	have	AUX
cet-1007	62	17	changed	change	VERB
cet-1007	62	18	significantly	significantly	ADV
cet-1007	62	19	on	on	ADP
cet-1007	62	20	the	the	DET
cet-1007	62	21	4th	4th	ADJ
cet-1007	62	22	dayafter	dayafter	NOUN
cet-1007	62	23	inoculation	inoculation	NOUN
cet-1007	62	24	with	with	ADP
cet-1007	62	25	yeast	yeast	NOUN
cet-1007	62	26	.	.	PUNCT
cet-1007	63	1	the	the	DET
cet-1007	63	2	cfus	cfus	NOUN
cet-1007	63	3	of	of	ADP
cet-1007	63	4	yeast	yeast	NOUN
cet-1007	63	5	in	in	ADP
cet-1007	63	6	the	the	DET
cet-1007	63	7	liquid	liquid	ADJ
cet-1007	63	8	extract	extract	NOUN
cet-1007	63	9	of	of	ADP
cet-1007	63	10	aconitum	aconitum	ADJ
cet-1007	63	11	root	root	NOUN
cet-1007	63	12	are	be	AUX
cet-1007	63	13	1.8×1010	1.8×1010	NUM
cet-1007	63	14	,	,	PUNCT
cet-1007	63	15	1.4×1012	1.4×1012	NUM
cet-1007	63	16	,	,	PUNCT
cet-1007	63	17	1.82×1011	1.82×1011	NUM
cet-1007	63	18	and	and	CCONJ
cet-1007	63	19	1.2×109	1.2×109	NUM
cet-1007	63	20	cfu	cfu	NOUN
cet-1007	63	21	/	/	SYM
cet-1007	63	22	ml	ml	X
cet-1007	63	23	on	on	ADP
cet-1007	63	24	the	the	DET
cet-1007	63	25	1st	1st	ADJ
cet-1007	63	26	,	,	PUNCT
cet-1007	63	27	2nd	2nd	ADJ
cet-1007	63	28	,	,	PUNCT
cet-1007	63	29	3rd	3rd	ADJ
cet-1007	63	30	and	and	CCONJ
cet-1007	63	31	4th	4th	ADJ
cet-1007	63	32	days	day	NOUN
cet-1007	63	33	,	,	PUNCT
cet-1007	63	34	respectively	respectively	ADV
cet-1007	63	35	,	,	PUNCT
cet-1007	63	36	which	which	PRON
cet-1007	63	37	indicates	indicate	VERB
cet-1007	63	38	that	that	SCONJ
cet-1007	63	39	the	the	DET
cet-1007	63	40	liquid	liquid	ADJ
cet-1007	63	41	extract	extract	NOUN
cet-1007	63	42	of	of	ADP
cet-1007	63	43	aconitum	aconitum	ADJ
cet-1007	63	44	root	root	NOUN
cet-1007	63	45	does	do	AUX
cet-1007	63	46	not	not	PART
cet-1007	63	47	inhibit	inhibit	VERB
cet-1007	63	48	the	the	DET
cet-1007	63	49	growth	growth	NOUN
cet-1007	63	50	of	of	ADP
cet-1007	63	51	the	the	DET
cet-1007	63	52	yeast	yeast	NOUN
cet-1007	63	53	.	.	PUNCT
cet-1007	64	1	there	there	PRON
cet-1007	64	2	are	be	VERB
cet-1007	64	3	more	more	ADJ
cet-1007	64	4	than	than	ADP
cet-1007	64	5	10	10	NUM
cet-1007	64	6	kinds	kind	NOUN
cet-1007	64	7	of	of	ADP
cet-1007	64	8	alkaloids	alkaloid	NOUN
cet-1007	64	9	in	in	ADP
cet-1007	64	10	aconitum	aconitum	ADJ
cet-1007	64	11	root	root	NOUN
cet-1007	64	12	.	.	PUNCT
cet-1007	65	1	after	after	ADP
cet-1007	65	2	the	the	DET
cet-1007	65	3	fermentation	fermentation	NOUN
cet-1007	65	4	by	by	ADP
cet-1007	65	5	saccharomyces	saccharomyce	NOUN
cet-1007	65	6	cerevisiae	cerevisiae	NOUN
cet-1007	65	7	,	,	PUNCT
cet-1007	65	8	the	the	DET
cet-1007	65	9	contents	content	NOUN
cet-1007	65	10	of	of	ADP
cet-1007	65	11	three	three	NUM
cet-1007	65	12	kinds	kind	NOUN
cet-1007	65	13	of	of	ADP
cet-1007	65	14	alkaloids	alkaloid	NOUN
cet-1007	65	15	,	,	PUNCT
cet-1007	65	16	i.e.	i.e.	X
cet-1007	65	17	mesaconitine	mesaconitine	NOUN
cet-1007	65	18	,	,	PUNCT
cet-1007	65	19	hypaconitine	hypaconitine	NOUN
cet-1007	65	20	and	and	CCONJ
cet-1007	65	21	songorine	songorine	NOUN
cet-1007	65	22	,	,	PUNCT
cet-1007	65	23	change	change	NOUN
cet-1007	65	24	in	in	ADP
cet-1007	65	25	the	the	DET
cet-1007	65	26	cultured	cultured	ADJ
cet-1007	65	27	liquids	liquid	NOUN
cet-1007	65	28	of	of	ADP
cet-1007	65	29	aconitum	aconitum	NOUN
cet-1007	65	30	.	.	PUNCT
cet-1007	66	1	hplc	hplc	NOUN
cet-1007	66	2	is	be	AUX
cet-1007	66	3	sufficient	sufficient	ADJ
cet-1007	66	4	for	for	ADP
cet-1007	66	5	good	good	ADJ
cet-1007	66	6	separation	separation	NOUN
cet-1007	66	7	of	of	ADP
cet-1007	66	8	the	the	DET
cet-1007	66	9	studied	study	VERB
cet-1007	66	10	alkaloids	alkaloid	NOUN
cet-1007	66	11	.	.	PUNCT
cet-1007	67	1	under	under	ADP
cet-1007	67	2	the	the	DET
cet-1007	67	3	given	give	VERB
cet-1007	67	4	hplc	hplc	NOUN
cet-1007	67	5	conditions	condition	NOUN
cet-1007	67	6	,	,	PUNCT
cet-1007	67	7	mesaconitine	mesaconitine	NOUN
cet-1007	67	8	(	(	PUNCT
cet-1007	67	9	rt	rt	PROPN
cet-1007	67	10	10.565	10.565	NUM
cet-1007	67	11	)	)	PUNCT
cet-1007	67	12	,	,	PUNCT
cet-1007	67	13	hypaconitine	hypaconitine	NOUN
cet-1007	67	14	(	(	PUNCT
cet-1007	67	15	rt	rt	PROPN
cet-1007	67	16	12.006	12.006	NUM
cet-1007	67	17	)	)	PUNCT
cet-1007	67	18	and	and	CCONJ
cet-1007	67	19	songorine	songorine	NOUN
cet-1007	67	20	(	(	PUNCT
cet-1007	67	21	rt	rt	NOUN
cet-1007	67	22	4.359	4.359	NUM
cet-1007	67	23	)	)	PUNCT
cet-1007	67	24	show	show	VERB
cet-1007	67	25	a	a	DET
cet-1007	67	26	significant	significant	ADJ
cet-1007	67	27	single	single	ADJ
cet-1007	67	28	peak	peak	NOUN
cet-1007	67	29	(	(	PUNCT
cet-1007	67	30	figure	figure	NOUN
cet-1007	67	31	2	2	NUM
cet-1007	67	32	,	,	PUNCT
cet-1007	67	33	3	3	NUM
cet-1007	67	34	,	,	PUNCT
cet-1007	67	35	4	4	NUM
cet-1007	67	36	)	)	PUNCT
cet-1007	67	37	.	.	PUNCT
cet-1007	68	1	after	after	ADP
cet-1007	68	2	fermentation	fermentation	NOUN
cet-1007	68	3	,	,	PUNCT
cet-1007	68	4	the	the	DET
cet-1007	68	5	songorine	songorine	NOUN
cet-1007	68	6	increases	increase	NOUN
cet-1007	68	7	while	while	SCONJ
cet-1007	68	8	the	the	DET
cet-1007	68	9	mesaconitine	mesaconitine	NOUN
cet-1007	68	10	and	and	CCONJ
cet-1007	68	11	the	the	DET
cet-1007	68	12	hypaconitine	hypaconitine	NOUN
cet-1007	68	13	all	all	PRON
cet-1007	68	14	decrease	decrease	NOUN
cet-1007	68	15	in	in	ADP
cet-1007	68	16	the	the	DET
cet-1007	68	17	cultured	cultured	ADJ
cet-1007	68	18	liquids	liquid	NOUN
cet-1007	68	19	of	of	ADP
cet-1007	68	20	aconitum	aconitum	NOUN
cet-1007	68	21	,	,	PUNCT
cet-1007	68	22	in	in	ADP
cet-1007	68	23	relation	relation	NOUN
cet-1007	68	24	to	to	ADP
cet-1007	68	25	the	the	DET
cet-1007	68	26	aqueous	aqueous	ADJ
cet-1007	68	27	extract	extract	NOUN
cet-1007	68	28	of	of	ADP
cet-1007	68	29	aconitum	aconitum	NOUN
cet-1007	68	30	(	(	PUNCT
cet-1007	68	31	figure	figure	NOUN
cet-1007	68	32	5	5	NUM
cet-1007	68	33	,	,	PUNCT
cet-1007	68	34	6	6	NUM
cet-1007	68	35	)	)	PUNCT
cet-1007	68	36	.	.	PUNCT
cet-1007	69	1	figure	figure	VERB
cet-1007	69	2	2	2	NUM
cet-1007	69	3	:	:	PUNCT
cet-1007	69	4	hplc	hplc	NOUN
cet-1007	69	5	chromatogram	chromatogram	PROPN
cet-1007	69	6	of	of	ADP
cet-1007	69	7	mesaconitine	mesaconitine	ADJ
cet-1007	69	8	figure	figure	NOUN
cet-1007	69	9	3	3	NUM
cet-1007	69	10	:	:	PUNCT
cet-1007	69	11	the	the	DET
cet-1007	69	12	hplc	hplc	NOUN
cet-1007	69	13	chromatogram	chromatogram	NOUN
cet-1007	69	14	of	of	ADP
cet-1007	69	15	hypaconitine	hypaconitine	NOUN
cet-1007	69	16	1251	1251	NUM
cet-1007	69	17	figure	figure	NOUN
cet-1007	69	18	4	4	NUM
cet-1007	69	19	:	:	PUNCT
cet-1007	69	20	hplc	hplc	NOUN
cet-1007	69	21	chromatogram	chromatogram	NOUN
cet-1007	69	22	of	of	ADP
cet-1007	69	23	songorine	songorine	ADJ
cet-1007	69	24	figure	figure	NOUN
cet-1007	69	25	5	5	NUM
cet-1007	69	26	:	:	PUNCT
cet-1007	69	27	hplc	hplc	NOUN
cet-1007	69	28	chromatogram	chromatogram	NOUN
cet-1007	69	29	of	of	ADP
cet-1007	69	30	the	the	DET
cet-1007	69	31	chloroform	chloroform	NOUN
cet-1007	69	32	extract	extract	NOUN
cet-1007	69	33	of	of	ADP
cet-1007	69	34	yeast	yeast	NOUN
cet-1007	69	35	-	-	PUNCT
cet-1007	69	36	fermented	ferment	VERB
cet-1007	69	37	aconitum	aconitum	NOUN
cet-1007	69	38	(	(	PUNCT
cet-1007	69	39	ceyfa	ceyfa	PROPN
cet-1007	69	40	)	)	PUNCT
cet-1007	69	41	figure	figure	NOUN
cet-1007	69	42	6	6	NUM
cet-1007	69	43	:	:	PUNCT
cet-1007	69	44	hplc	hplc	NOUN
cet-1007	69	45	chromatogram	chromatogram	NOUN
cet-1007	69	46	of	of	ADP
cet-1007	69	47	the	the	DET
cet-1007	69	48	chloroform	chloroform	NOUN
cet-1007	69	49	extract	extract	NOUN
cet-1007	69	50	of	of	ADP
cet-1007	69	51	aconitum	aconitum	PROPN
cet-1007	69	52	(	(	PUNCT
cet-1007	69	53	cea	cea	PROPN
cet-1007	69	54	)	)	PUNCT
cet-1007	69	55	table	table	NOUN
cet-1007	69	56	1	1	NUM
cet-1007	69	57	:	:	PUNCT
cet-1007	69	58	peak	peak	NOUN
cet-1007	69	59	height	height	NOUN
cet-1007	69	60	(	(	PUNCT
cet-1007	69	61	mau	mau	PROPN
cet-1007	69	62	)	)	PUNCT
cet-1007	69	63	and	and	CCONJ
cet-1007	69	64	area	area	NOUN
cet-1007	69	65	(	(	PUNCT
cet-1007	69	66	%	%	INTJ
cet-1007	69	67	)	)	PUNCT
cet-1007	69	68	of	of	ADP
cet-1007	69	69	m	m	PROPN
cet-1007	69	70	(	(	PUNCT
cet-1007	69	71	mesaconitine	mesaconitine	NOUN
cet-1007	69	72	)	)	PUNCT
cet-1007	69	73	,	,	PUNCT
cet-1007	69	74	h	h	NOUN
cet-1007	69	75	(	(	PUNCT
cet-1007	69	76	hypaconitine	hypaconitine	NOUN
cet-1007	69	77	)	)	PUNCT
cet-1007	69	78	and	and	CCONJ
cet-1007	69	79	s	s	PROPN
cet-1007	69	80	(	(	PUNCT
cet-1007	69	81	songorine	songorine	NOUN
cet-1007	69	82	)	)	PUNCT
cet-1007	69	83	in	in	ADP
cet-1007	69	84	the	the	DET
cet-1007	69	85	chloroform	chloroform	NOUN
cet-1007	69	86	extract	extract	NOUN
cet-1007	69	87	of	of	ADP
cet-1007	69	88	aconitum	aconitum	ADJ
cet-1007	69	89	and	and	CCONJ
cet-1007	69	90	yeast	yeast	NOUN
cet-1007	69	91	-	-	PUNCT
cet-1007	69	92	fermented	ferment	VERB
cet-1007	69	93	aconitum	aconitum	ADJ
cet-1007	69	94	sample	sample	NOUN
cet-1007	69	95	height	height	NOUN
cet-1007	69	96	(	(	PUNCT
cet-1007	69	97	mau	mau	PROPN
cet-1007	69	98	)	)	PUNCT
cet-1007	69	99	area	area	NOUN
cet-1007	69	100	(	(	PUNCT
cet-1007	69	101	%	%	INTJ
cet-1007	69	102	)	)	PUNCT
cet-1007	70	1	m	m	VERB
cet-1007	70	2	h	h	NOUN
cet-1007	70	3	s	s	PART
cet-1007	71	1	m	m	VERB
cet-1007	71	2	h	h	NOUN
cet-1007	71	3	s	s	PART
cet-1007	71	4	yeast	yeast	NOUN
cet-1007	71	5	-	-	PUNCT
cet-1007	71	6	fermented	ferment	VERB
cet-1007	71	7	aconitum	aconitum	NOUN
cet-1007	71	8	66	66	NUM
cet-1007	71	9	82	82	NUM
cet-1007	71	10	753	753	NUM
cet-1007	71	11	8.9	8.9	NUM
cet-1007	71	12	14.8	14.8	NUM
cet-1007	71	13	34.5	34.5	NUM
cet-1007	71	14	aconitum	aconitum	NOUN
cet-1007	71	15	66	66	NUM
cet-1007	71	16	332	332	NUM
cet-1007	71	17	40	40	NUM
cet-1007	71	18	11.7	11.7	NUM
cet-1007	71	19	63.6	63.6	NUM
cet-1007	71	20	7.5	7.5	NUM
cet-1007	71	21	the	the	DET
cet-1007	71	22	above	above	ADJ
cet-1007	71	23	results	result	NOUN
cet-1007	71	24	demonstrate	demonstrate	VERB
cet-1007	71	25	that	that	SCONJ
cet-1007	71	26	the	the	DET
cet-1007	71	27	yeast	yeast	NOUN
cet-1007	71	28	produces	produce	VERB
cet-1007	71	29	a	a	DET
cet-1007	71	30	less	less	ADJ
cet-1007	71	31	effects	effect	NOUN
cet-1007	71	32	on	on	ADP
cet-1007	71	33	the	the	DET
cet-1007	71	34	biotransformation	biotransformation	NOUN
cet-1007	71	35	of	of	ADP
cet-1007	71	36	mesaconitine	mesaconitine	NOUN
cet-1007	71	37	.	.	PUNCT
cet-1007	72	1	there	there	PRON
cet-1007	72	2	is	be	VERB
cet-1007	72	3	a	a	DET
cet-1007	72	4	hydroxide	hydroxide	NOUN
cet-1007	72	5	radical	radical	ADJ
cet-1007	72	6	linking	linking	NOUN
cet-1007	72	7	to	to	ADP
cet-1007	72	8	c3	c3	PROPN
cet-1007	72	9	of	of	ADP
cet-1007	72	10	mesaconitine	mesaconitine	NOUN
cet-1007	72	11	as	as	ADP
cet-1007	72	12	the	the	DET
cet-1007	72	13	only	only	ADJ
cet-1007	72	14	difference	difference	NOUN
cet-1007	72	15	between	between	ADP
cet-1007	72	16	mesaconitine	mesaconitine	ADJ
cet-1007	72	17	and	and	CCONJ
cet-1007	72	18	hypaconitinein	hypaconitinein	ADJ
cet-1007	72	19	structures	structure	NOUN
cet-1007	72	20	(	(	PUNCT
cet-1007	72	21	figure	figure	NOUN
cet-1007	72	22	1	1	NUM
cet-1007	72	23	)	)	PUNCT
cet-1007	72	24	.	.	PUNCT
cet-1007	73	1	itis	itis	NOUN
cet-1007	73	2	speculated	speculate	VERB
cet-1007	73	3	that	that	SCONJ
cet-1007	73	4	the	the	DET
cet-1007	73	5	hydroxide	hydroxide	NOUN
cet-1007	73	6	radical	radical	NOUN
cet-1007	73	7	may	may	AUX
cet-1007	73	8	be	be	AUX
cet-1007	73	9	a	a	DET
cet-1007	73	10	sterichindrance	sterichindrance	NOUN
cet-1007	73	11	for	for	ADP
cet-1007	73	12	yeast	yeast	NOUN
cet-1007	73	13	enzymes	enzyme	NOUN
cet-1007	73	14	to	to	PART
cet-1007	73	15	convert	convert	VERB
cet-1007	73	16	mesaconitine	mesaconitine	NOUN
cet-1007	73	17	into	into	ADP
cet-1007	73	18	other	other	ADJ
cet-1007	73	19	molecules	molecule	NOUN
cet-1007	73	20	.	.	PUNCT
cet-1007	74	1	the	the	DET
cet-1007	74	2	conversion	conversion	NOUN
cet-1007	74	3	of	of	ADP
cet-1007	74	4	hypaconitine	hypaconitine	NOUN
cet-1007	74	5	into	into	ADP
cet-1007	74	6	songorine	songorine	NOUN
cet-1007	74	7	easily	easily	ADV
cet-1007	74	8	takes	take	VERB
cet-1007	74	9	place	place	NOUN
cet-1007	74	10	in	in	ADP
cet-1007	74	11	this	this	DET
cet-1007	74	12	experiment	experiment	NOUN
cet-1007	74	13	involving	involve	VERB
cet-1007	74	14	a	a	DET
cet-1007	74	15	wide	wide	ADJ
cet-1007	74	16	variety	variety	NOUN
cet-1007	74	17	of	of	ADP
cet-1007	74	18	reactions	reaction	NOUN
cet-1007	74	19	.	.	PUNCT
cet-1007	75	1	dehydrogenases	dehydrogenase	NOUN
cet-1007	75	2	are	be	AUX
cet-1007	75	3	widely	widely	ADV
cet-1007	75	4	existed	exist	VERB
cet-1007	75	5	in	in	ADP
cet-1007	75	6	yeast	yeast	NOUN
cet-1007	75	7	(	(	PUNCT
cet-1007	75	8	pereira	pereira	PROPN
cet-1007	75	9	,	,	PUNCT
cet-1007	75	10	1998	1998	NUM
cet-1007	75	11	)	)	PUNCT
cet-1007	75	12	.	.	PUNCT
cet-1007	76	1	some	some	DET
cet-1007	76	2	chemical	chemical	ADJ
cet-1007	76	3	functional	functional	ADJ
cet-1007	76	4	groups	group	NOUN
cet-1007	76	5	of	of	ADP
cet-1007	76	6	hypaconitine	hypaconitine	NOUN
cet-1007	76	7	,	,	PUNCT
cet-1007	76	8	for	for	ADP
cet-1007	76	9	example	example	NOUN
cet-1007	76	10	,	,	PUNCT
cet-1007	76	11	the	the	DET
cet-1007	76	12	hydroxide	hydroxide	NOUN
cet-1007	76	13	radical	radical	NOUN
cet-1007	76	14	that	that	PRON
cet-1007	76	15	binds	bind	VERB
cet-1007	76	16	c14	c14	NOUN
cet-1007	76	17	,	,	PUNCT
cet-1007	76	18	should	should	AUX
cet-1007	76	19	at	at	ADV
cet-1007	76	20	least	least	ADJ
cet-1007	76	21	be	be	AUX
cet-1007	76	22	oxidized	oxidize	VERB
cet-1007	76	23	by	by	ADP
cet-1007	76	24	yeast	yeast	NOUN
cet-1007	76	25	dehydrogenases	dehydrogenase	NOUN
cet-1007	76	26	.	.	PUNCT
cet-1007	77	1	however	however	ADV
cet-1007	77	2	,	,	PUNCT
cet-1007	77	3	the	the	DET
cet-1007	77	4	exact	exact	ADJ
cet-1007	77	5	metabolic	metabolic	NOUN
cet-1007	77	6	pathways	pathway	NOUN
cet-1007	77	7	need	need	VERB
cet-1007	77	8	to	to	PART
cet-1007	77	9	be	be	AUX
cet-1007	77	10	further	far	ADV
cet-1007	77	11	studied	study	VERB
cet-1007	77	12	in	in	ADP
cet-1007	77	13	the	the	DET
cet-1007	77	14	future	future	ADJ
cet-1007	77	15	works	work	NOUN
cet-1007	77	16	.	.	PUNCT
cet-1007	78	1	1252	1252	NUM
cet-1007	78	2	tail	tail	NOUN
cet-1007	78	3	clip	clip	NOUN
cet-1007	78	4	test	test	NOUN
cet-1007	78	5	,	,	PUNCT
cet-1007	78	6	as	as	ADP
cet-1007	78	7	a	a	DET
cet-1007	78	8	simple	simple	ADJ
cet-1007	78	9	means	mean	NOUN
cet-1007	78	10	of	of	ADP
cet-1007	78	11	testing	test	VERB
cet-1007	78	12	analgesic	analgesic	ADJ
cet-1007	78	13	drugs	drug	NOUN
cet-1007	78	14	,	,	PUNCT
cet-1007	78	15	is	be	AUX
cet-1007	78	16	based	base	VERB
cet-1007	78	17	on	on	ADP
cet-1007	78	18	a	a	DET
cet-1007	78	19	reflex	reflex	ADJ
cet-1007	78	20	mechanism	mechanism	NOUN
cet-1007	78	21	which	which	PRON
cet-1007	78	22	involves	involve	VERB
cet-1007	78	23	the	the	DET
cet-1007	78	24	higher	high	ADJ
cet-1007	78	25	center	center	NOUN
cet-1007	78	26	(	(	PUNCT
cet-1007	78	27	bianchi	bianchi	NOUN
cet-1007	78	28	and	and	CCONJ
cet-1007	78	29	franceschini	franceschini	NOUN
cet-1007	78	30	,	,	PUNCT
cet-1007	78	31	1954	1954	NUM
cet-1007	78	32	)	)	PUNCT
cet-1007	78	33	.	.	PUNCT
cet-1007	79	1	the	the	DET
cet-1007	79	2	earlier	early	ADJ
cet-1007	79	3	studies	study	NOUN
cet-1007	79	4	reveal	reveal	VERB
cet-1007	79	5	that	that	SCONJ
cet-1007	79	6	the	the	DET
cet-1007	79	7	tail	tail	NOUN
cet-1007	79	8	clip	clip	NOUN
cet-1007	79	9	test	test	NOUN
cet-1007	79	10	is	be	AUX
cet-1007	79	11	applicable	applicable	ADJ
cet-1007	79	12	to	to	PART
cet-1007	79	13	detect	detect	VERB
cet-1007	79	14	the	the	DET
cet-1007	79	15	analgesic	analgesic	ADJ
cet-1007	79	16	activity	activity	NOUN
cet-1007	79	17	of	of	ADP
cet-1007	79	18	aconitum	aconitum	NOUN
cet-1007	79	19	(	(	PUNCT
cet-1007	79	20	hikino	hikino	X
cet-1007	79	21	et	et	PROPN
cet-1007	79	22	al	al	PROPN
cet-1007	79	23	.	.	PROPN
cet-1007	79	24	,	,	PUNCT
cet-1007	79	25	1979	1979	NUM
cet-1007	79	26	)	)	PUNCT
cet-1007	79	27	.	.	PUNCT
cet-1007	80	1	the	the	DET
cet-1007	80	2	current	current	ADJ
cet-1007	80	3	results	result	NOUN
cet-1007	80	4	(	(	PUNCT
cet-1007	80	5	table	table	NOUN
cet-1007	80	6	2	2	NUM
cet-1007	80	7	)	)	PUNCT
cet-1007	80	8	show	show	VERB
cet-1007	80	9	that	that	SCONJ
cet-1007	80	10	the	the	DET
cet-1007	80	11	two	two	NUM
cet-1007	80	12	kinds	kind	NOUN
cet-1007	80	13	of	of	ADP
cet-1007	80	14	chloroform	chloroform	NOUN
cet-1007	80	15	extracts	extract	NOUN
cet-1007	80	16	of	of	ADP
cet-1007	80	17	aconitum	aconitum	PROPN
cet-1007	80	18	exhibit	exhibit	NOUN
cet-1007	80	19	dose	dose	NOUN
cet-1007	80	20	-	-	PUNCT
cet-1007	80	21	dependent	dependent	ADJ
cet-1007	80	22	analgesic	analgesic	ADJ
cet-1007	80	23	effects	effect	NOUN
cet-1007	80	24	.	.	PUNCT
cet-1007	81	1	the	the	DET
cet-1007	81	2	ed50	ed50	PROPN
cet-1007	81	3	of	of	ADP
cet-1007	81	4	the	the	DET
cet-1007	81	5	ceyfa	ceyfa	NOUN
cet-1007	81	6	is	be	AUX
cet-1007	81	7	0.44	0.44	NUM
cet-1007	81	8	±	±	NUM
cet-1007	81	9	0.12	0.12	NUM
cet-1007	81	10	mg	mg	PROPN
cet-1007	81	11	/	/	SYM
cet-1007	81	12	kg	kg	PROPN
cet-1007	81	13	and	and	CCONJ
cet-1007	81	14	the	the	DET
cet-1007	81	15	cea	cea	PROPN
cet-1007	81	16	0.25±0.04mg	0.25±0.04mg	PROPN
cet-1007	81	17	/	/	SYM
cet-1007	81	18	kg	kg	PROPN
cet-1007	81	19	.	.	PUNCT
cet-1007	82	1	as	as	SCONJ
cet-1007	82	2	judged	judge	VERB
cet-1007	82	3	from	from	ADP
cet-1007	82	4	the	the	DET
cet-1007	82	5	ed50	ed50	PROPN
cet-1007	82	6	values	value	NOUN
cet-1007	82	7	,	,	PUNCT
cet-1007	82	8	the	the	DET
cet-1007	82	9	cea	cea	PROPN
cet-1007	82	10	is	be	AUX
cet-1007	82	11	about	about	ADV
cet-1007	82	12	2	2	NUM
cet-1007	82	13	times	time	NOUN
cet-1007	82	14	than	than	ADP
cet-1007	82	15	the	the	DET
cet-1007	82	16	ceyfa	ceyfa	NOUN
cet-1007	82	17	in	in	ADP
cet-1007	82	18	suppressing	suppress	VERB
cet-1007	82	19	clip	clip	NOUN
cet-1007	82	20	-	-	PUNCT
cet-1007	82	21	induced	induce	VERB
cet-1007	82	22	stimuli	stimulus	NOUN
cet-1007	82	23	.	.	PUNCT
cet-1007	83	1	hypaconitine	hypaconitine	NOUN
cet-1007	83	2	and	and	CCONJ
cet-1007	83	3	mesaconitine	mesaconitine	NOUN
cet-1007	83	4	are	be	AUX
cet-1007	83	5	known	know	VERB
cet-1007	83	6	as	as	ADP
cet-1007	83	7	the	the	DET
cet-1007	83	8	active	active	ADJ
cet-1007	83	9	compounds	compound	NOUN
cet-1007	83	10	of	of	ADP
cet-1007	83	11	aconitum	aconitum	NOUN
cet-1007	83	12	for	for	ADP
cet-1007	83	13	pain	pain	NOUN
cet-1007	83	14	management	management	NOUN
cet-1007	83	15	(	(	PUNCT
cet-1007	83	16	ameri	ameri	PROPN
cet-1007	83	17	,	,	PUNCT
cet-1007	83	18	1998	1998	NUM
cet-1007	83	19	)	)	PUNCT
cet-1007	83	20	.	.	PUNCT
cet-1007	84	1	interestingly	interestingly	ADV
cet-1007	84	2	the	the	DET
cet-1007	84	3	hypaconitine	hypaconitine	NOUN
cet-1007	84	4	in	in	ADP
cet-1007	84	5	cea	cea	PROPN
cet-1007	84	6	is	be	AUX
cet-1007	84	7	about	about	ADV
cet-1007	84	8	6	6	NUM
cet-1007	84	9	times	time	NOUN
cet-1007	84	10	than	than	ADP
cet-1007	84	11	that	that	PRON
cet-1007	84	12	in	in	ADP
cet-1007	84	13	ceyfa	ceyfa	NOUN
cet-1007	84	14	and	and	CCONJ
cet-1007	84	15	the	the	DET
cet-1007	84	16	analgesic	analgesic	ADJ
cet-1007	84	17	effect	effect	NOUN
cet-1007	84	18	of	of	ADP
cet-1007	84	19	cea	cea	PROPN
cet-1007	84	20	should	should	AUX
cet-1007	84	21	be	be	AUX
cet-1007	84	22	much	much	ADV
cet-1007	84	23	more	more	ADV
cet-1007	84	24	potent	potent	ADJ
cet-1007	84	25	than	than	ADP
cet-1007	84	26	ceyfa	ceyfa	PROPN
cet-1007	84	27	,	,	PUNCT
cet-1007	84	28	but	but	CCONJ
cet-1007	84	29	there	there	PRON
cet-1007	84	30	is	be	VERB
cet-1007	84	31	no	no	DET
cet-1007	84	32	such	such	DET
cet-1007	84	33	a	a	DET
cet-1007	84	34	big	big	ADJ
cet-1007	84	35	difference	difference	NOUN
cet-1007	84	36	between	between	ADP
cet-1007	84	37	cea	cea	PROPN
cet-1007	84	38	and	and	CCONJ
cet-1007	84	39	ceyfa	ceyfa	PROPN
cet-1007	84	40	in	in	ADP
cet-1007	84	41	analgesic	analgesic	ADJ
cet-1007	84	42	activity	activity	NOUN
cet-1007	84	43	.	.	PUNCT
cet-1007	85	1	this	this	PRON
cet-1007	85	2	can	can	AUX
cet-1007	85	3	be	be	AUX
cet-1007	85	4	explained	explain	VERB
cet-1007	85	5	by	by	ADP
cet-1007	85	6	the	the	DET
cet-1007	85	7	fact	fact	NOUN
cet-1007	85	8	that	that	SCONJ
cet-1007	85	9	songorine	songorine	NOUN
cet-1007	85	10	increases	increase	NOUN
cet-1007	85	11	to	to	ADP
cet-1007	85	12	about	about	ADV
cet-1007	85	13	5	5	NUM
cet-1007	85	14	times	time	NOUN
cet-1007	85	15	in	in	ADP
cet-1007	85	16	ceyfa	ceyfa	NOUN
cet-1007	85	17	than	than	ADP
cet-1007	85	18	in	in	ADP
cet-1007	85	19	cea	cea	PROPN
cet-1007	85	20	.	.	PUNCT
cet-1007	86	1	the	the	DET
cet-1007	86	2	results	result	NOUN
cet-1007	86	3	suggest	suggest	VERB
cet-1007	86	4	that	that	SCONJ
cet-1007	86	5	songorine	songorine	NOUN
cet-1007	86	6	may	may	AUX
cet-1007	86	7	be	be	AUX
cet-1007	86	8	also	also	ADV
cet-1007	86	9	a	a	DET
cet-1007	86	10	compound	compound	NOUN
cet-1007	86	11	with	with	ADP
cet-1007	86	12	analgesic	analgesic	ADJ
cet-1007	86	13	activity	activity	NOUN
cet-1007	86	14	.	.	PUNCT
cet-1007	87	1	this	this	DET
cet-1007	87	2	assumption	assumption	NOUN
cet-1007	87	3	deserves	deserve	VERB
cet-1007	87	4	to	to	PART
cet-1007	87	5	be	be	AUX
cet-1007	87	6	further	far	ADV
cet-1007	87	7	verified	verify	VERB
cet-1007	87	8	in	in	ADP
cet-1007	87	9	the	the	DET
cet-1007	87	10	futureworks	futurework	NOUN
cet-1007	87	11	.	.	PUNCT
cet-1007	88	1	in	in	ADP
cet-1007	88	2	order	order	NOUN
cet-1007	88	3	to	to	PART
cet-1007	88	4	investigate	investigate	VERB
cet-1007	88	5	whether	whether	SCONJ
cet-1007	88	6	fermentation	fermentation	NOUN
cet-1007	88	7	process	process	NOUN
cet-1007	88	8	can	can	AUX
cet-1007	88	9	reduce	reduce	VERB
cet-1007	88	10	the	the	DET
cet-1007	88	11	toxicity	toxicity	NOUN
cet-1007	88	12	of	of	ADP
cet-1007	88	13	aconitum	aconitum	NOUN
cet-1007	88	14	,	,	PUNCT
cet-1007	88	15	mice	mouse	NOUN
cet-1007	88	16	are	be	AUX
cet-1007	88	17	used	use	VERB
cet-1007	88	18	to	to	PART
cet-1007	88	19	determine	determine	VERB
cet-1007	88	20	the	the	DET
cet-1007	88	21	median	median	ADJ
cet-1007	88	22	lethal	lethal	ADJ
cet-1007	88	23	dose	dose	NOUN
cet-1007	88	24	(	(	PUNCT
cet-1007	88	25	ld50	ld50	PROPN
cet-1007	88	26	)	)	PUNCT
cet-1007	88	27	of	of	ADP
cet-1007	88	28	the	the	DET
cet-1007	88	29	chloroform	chloroform	NOUN
cet-1007	88	30	extract	extract	NOUN
cet-1007	88	31	of	of	ADP
cet-1007	88	32	aconitum	aconitum	PROPN
cet-1007	88	33	(	(	PUNCT
cet-1007	88	34	cea	cea	PROPN
cet-1007	88	35	)	)	PUNCT
cet-1007	88	36	and	and	CCONJ
cet-1007	88	37	the	the	DET
cet-1007	88	38	chloroform	chloroform	NOUN
cet-1007	88	39	extract	extract	NOUN
cet-1007	88	40	of	of	ADP
cet-1007	88	41	yeast	yeast	NOUN
cet-1007	88	42	-	-	PUNCT
cet-1007	88	43	fermented	ferment	VERB
cet-1007	88	44	aconitum	aconitum	NOUN
cet-1007	88	45	(	(	PUNCT
cet-1007	88	46	ceyfa	ceyfa	PROPN
cet-1007	88	47	)	)	PUNCT
cet-1007	88	48	.	.	PUNCT
cet-1007	89	1	the	the	DET
cet-1007	89	2	results	result	NOUN
cet-1007	89	3	show	show	VERB
cet-1007	89	4	that	that	SCONJ
cet-1007	89	5	the	the	DET
cet-1007	89	6	fermentation	fermentation	NOUN
cet-1007	89	7	may	may	AUX
cet-1007	89	8	greatly	greatly	ADV
cet-1007	89	9	relieve	relieve	VERB
cet-1007	89	10	the	the	DET
cet-1007	89	11	toxicity	toxicity	NOUN
cet-1007	89	12	of	of	ADP
cet-1007	89	13	aconitum	aconitum	ADJ
cet-1007	89	14	(	(	PUNCT
cet-1007	89	15	table	table	NOUN
cet-1007	89	16	3	3	NUM
cet-1007	89	17	)	)	PUNCT
cet-1007	89	18	with	with	ADP
cet-1007	89	19	ld50	ld50	PROPN
cet-1007	89	20	value	value	NOUN
cet-1007	89	21	of	of	ADP
cet-1007	89	22	cea	cea	PROPN
cet-1007	89	23	about	about	ADP
cet-1007	89	24	1.44±0.07mg	1.44±0.07mg	NUM
cet-1007	89	25	/	/	SYM
cet-1007	89	26	kg	kg	PROPN
cet-1007	89	27	.	.	PUNCT
cet-1007	90	1	this	this	DET
cet-1007	90	2	result	result	NOUN
cet-1007	90	3	coincides	coincide	VERB
cet-1007	90	4	with	with	ADP
cet-1007	90	5	that	that	PRON
cet-1007	90	6	in	in	ADP
cet-1007	90	7	earlier	early	ADJ
cet-1007	90	8	study	study	NOUN
cet-1007	90	9	(	(	PUNCT
cet-1007	90	10	hikino	hikino	X
cet-1007	90	11	et	et	PROPN
cet-1007	90	12	al	al	PROPN
cet-1007	90	13	.	.	PROPN
cet-1007	90	14	,	,	PUNCT
cet-1007	90	15	1979	1979	NUM
cet-1007	90	16	)	)	PUNCT
cet-1007	90	17	at	at	ADP
cet-1007	90	18	the	the	DET
cet-1007	90	19	hypaconitine	hypaconitine	NOUN
cet-1007	90	20	ld50(mice	ld50(mice	PROPN
cet-1007	90	21	,	,	PUNCT
cet-1007	90	22	s.c	s.c	PROPN
cet-1007	90	23	.	.	PROPN
cet-1007	90	24	)	)	PUNCT
cet-1007	90	25	of	of	ADP
cet-1007	90	26	1.19	1.19	NUM
cet-1007	90	27	mg	mg	NUM
cet-1007	90	28	/	/	SYM
cet-1007	90	29	kg	kg	PROPN
cet-1007	90	30	.	.	PUNCT
cet-1007	91	1	the	the	DET
cet-1007	91	2	cea	cea	PROPN
cet-1007	91	3	contains	contain	VERB
cet-1007	91	4	many	many	ADJ
cet-1007	91	5	compounds	compound	NOUN
cet-1007	91	6	but	but	CCONJ
cet-1007	91	7	the	the	DET
cet-1007	91	8	percentage	percentage	NOUN
cet-1007	91	9	of	of	ADP
cet-1007	91	10	hypaconitine	hypaconitine	NOUN
cet-1007	91	11	in	in	ADP
cet-1007	91	12	cea	cea	PROPN
cet-1007	91	13	is	be	AUX
cet-1007	91	14	only	only	ADV
cet-1007	91	15	63.6	63.6	NUM
cet-1007	91	16	%	%	NOUN
cet-1007	91	17	.	.	PUNCT
cet-1007	92	1	the	the	DET
cet-1007	92	2	somewhat	somewhat	ADV
cet-1007	92	3	lower	low	ADJ
cet-1007	92	4	acute	acute	ADJ
cet-1007	92	5	toxicity	toxicity	NOUN
cet-1007	92	6	in	in	ADP
cet-1007	92	7	this	this	DET
cet-1007	92	8	experiment	experiment	NOUN
cet-1007	92	9	may	may	AUX
cet-1007	92	10	be	be	AUX
cet-1007	92	11	caused	cause	VERB
cet-1007	92	12	due	due	ADP
cet-1007	92	13	to	to	ADP
cet-1007	92	14	the	the	DET
cet-1007	92	15	method	method	NOUN
cet-1007	92	16	of	of	ADP
cet-1007	92	17	drug	drug	NOUN
cet-1007	92	18	application	application	NOUN
cet-1007	92	19	and	and	CCONJ
cet-1007	92	20	the	the	DET
cet-1007	92	21	impurity	impurity	NOUN
cet-1007	92	22	of	of	ADP
cet-1007	92	23	cea	cea	PROPN
cet-1007	92	24	.	.	PUNCT
cet-1007	93	1	the	the	DET
cet-1007	93	2	ld50	ld50	PROPN
cet-1007	93	3	of	of	ADP
cet-1007	93	4	ceyfa	ceyfa	PROPN
cet-1007	93	5	is	be	AUX
cet-1007	93	6	13.80±1.92mg	13.80±1.92mg	NUM
cet-1007	93	7	/	/	SYM
cet-1007	93	8	kg	kg	PROPN
cet-1007	93	9	,	,	PUNCT
cet-1007	93	10	which	which	PRON
cet-1007	93	11	indicates	indicate	VERB
cet-1007	93	12	obviously	obviously	ADV
cet-1007	93	13	that	that	SCONJ
cet-1007	93	14	the	the	DET
cet-1007	93	15	toxicity	toxicity	NOUN
cet-1007	93	16	of	of	ADP
cet-1007	93	17	ceyfa	ceyfa	NOUN
cet-1007	93	18	is	be	AUX
cet-1007	93	19	lower	low	ADJ
cet-1007	93	20	than	than	ADP
cet-1007	93	21	that	that	PRON
cet-1007	93	22	of	of	ADP
cet-1007	93	23	cea	cea	PROPN
cet-1007	93	24	.	.	PUNCT
cet-1007	94	1	two	two	NUM
cet-1007	94	2	factors	factor	NOUN
cet-1007	94	3	might	might	AUX
cet-1007	94	4	lead	lead	VERB
cet-1007	94	5	to	to	ADP
cet-1007	94	6	the	the	DET
cet-1007	94	7	reduction	reduction	NOUN
cet-1007	94	8	of	of	ADP
cet-1007	94	9	toxicity	toxicity	NOUN
cet-1007	94	10	in	in	ADP
cet-1007	94	11	ceyfa	ceyfa	PROPN
cet-1007	94	12	.	.	PUNCT
cet-1007	95	1	first	first	ADV
cet-1007	95	2	,	,	PUNCT
cet-1007	95	3	the	the	DET
cet-1007	95	4	percentage	percentage	NOUN
cet-1007	95	5	of	of	ADP
cet-1007	95	6	hypaconitine	hypaconitine	NOUN
cet-1007	95	7	in	in	ADP
cet-1007	95	8	the	the	DET
cet-1007	95	9	ceyfa	ceyfa	NOUN
cet-1007	95	10	is	be	AUX
cet-1007	95	11	reduced	reduce	VERB
cet-1007	95	12	from	from	ADP
cet-1007	95	13	63.6	63.6	NUM
cet-1007	95	14	%	%	NOUN
cet-1007	95	15	to	to	ADP
cet-1007	95	16	14.8	14.8	NUM
cet-1007	95	17	%	%	NOUN
cet-1007	95	18	in	in	ADP
cet-1007	95	19	relation	relation	NOUN
cet-1007	95	20	to	to	ADP
cet-1007	95	21	cea	cea	PROPN
cet-1007	95	22	.	.	PUNCT
cet-1007	96	1	it	it	PRON
cet-1007	96	2	is	be	AUX
cet-1007	96	3	known	know	VERB
cet-1007	96	4	that	that	SCONJ
cet-1007	96	5	activation	activation	NOUN
cet-1007	96	6	of	of	ADP
cet-1007	96	7	na+	na+	NOUN
cet-1007	96	8	channels	channel	NOUN
cet-1007	96	9	by	by	ADP
cet-1007	96	10	aconitine	aconitine	NOUN
cet-1007	96	11	and	and	CCONJ
cet-1007	96	12	hypaconitine	hypaconitine	NOUN
cet-1007	96	13	is	be	AUX
cet-1007	96	14	responsible	responsible	ADJ
cet-1007	96	15	for	for	ADP
cet-1007	96	16	their	their	PRON
cet-1007	96	17	cardiotoxic	cardiotoxic	NOUN
cet-1007	96	18	.	.	PUNCT
cet-1007	97	1	the	the	DET
cet-1007	97	2	reduction	reduction	NOUN
cet-1007	97	3	of	of	ADP
cet-1007	97	4	hypaconitine	hypaconitine	NOUN
cet-1007	97	5	in	in	ADP
cet-1007	97	6	ceyfa	ceyfa	PROPN
cet-1007	97	7	should	should	AUX
cet-1007	97	8	cause	cause	VERB
cet-1007	97	9	the	the	DET
cet-1007	97	10	mitigation	mitigation	NOUN
cet-1007	97	11	of	of	ADP
cet-1007	97	12	toxicity	toxicity	NOUN
cet-1007	97	13	of	of	ADP
cet-1007	97	14	ceyfa	ceyfa	NOUN
cet-1007	97	15	theoretically	theoretically	ADV
cet-1007	97	16	.	.	PUNCT
cet-1007	98	1	secondly	secondly	ADV
cet-1007	98	2	,	,	PUNCT
cet-1007	98	3	songorine	songorine	NOUN
cet-1007	98	4	increases	increase	NOUN
cet-1007	98	5	relatively	relatively	ADV
cet-1007	98	6	in	in	ADP
cet-1007	98	7	ceyfa	ceyfa	PROPN
cet-1007	98	8	.	.	PUNCT
cet-1007	99	1	songorine	songorine	PROPN
cet-1007	99	2	was	be	AUX
cet-1007	99	3	reported	report	VERB
cet-1007	99	4	once	once	ADV
cet-1007	99	5	to	to	PART
cet-1007	99	6	have	have	VERB
cet-1007	99	7	antiarrhythmic	antiarrhythmic	ADJ
cet-1007	99	8	actions	action	NOUN
cet-1007	99	9	(	(	PUNCT
cet-1007	99	10	ameri	ameri	PROPN
cet-1007	99	11	,	,	PUNCT
cet-1007	99	12	1998	1998	NUM
cet-1007	99	13	)	)	PUNCT
cet-1007	99	14	,	,	PUNCT
cet-1007	99	15	therefore	therefore	ADV
cet-1007	99	16	,	,	PUNCT
cet-1007	99	17	it	it	PRON
cet-1007	99	18	can	can	AUX
cet-1007	99	19	resist	resist	VERB
cet-1007	99	20	the	the	DET
cet-1007	99	21	cardiotoxicity	cardiotoxicity	NOUN
cet-1007	99	22	produced	produce	VERB
cet-1007	99	23	by	by	ADP
cet-1007	99	24	aconitine	aconitine	NOUN
cet-1007	99	25	,	,	PUNCT
cet-1007	99	26	hypaconitine	hypaconitine	NOUN
cet-1007	99	27	and	and	CCONJ
cet-1007	99	28	so	so	ADV
cet-1007	99	29	on	on	ADV
cet-1007	99	30	.	.	PUNCT
cet-1007	100	1	it	it	PRON
cet-1007	100	2	is	be	AUX
cet-1007	100	3	certain	certain	ADJ
cet-1007	100	4	that	that	SCONJ
cet-1007	100	5	the	the	DET
cet-1007	100	6	toxicity	toxicity	NOUN
cet-1007	100	7	of	of	ADP
cet-1007	100	8	aconitum	aconitum	NOUN
cet-1007	100	9	can	can	AUX
cet-1007	100	10	be	be	AUX
cet-1007	100	11	reduced	reduce	VERB
cet-1007	100	12	to	to	ADP
cet-1007	100	13	a	a	DET
cet-1007	100	14	relatively	relatively	ADV
cet-1007	100	15	low	low	ADJ
cet-1007	100	16	level	level	NOUN
cet-1007	100	17	after	after	SCONJ
cet-1007	100	18	it	it	PRON
cet-1007	100	19	is	be	AUX
cet-1007	100	20	fermented	ferment	VERB
cet-1007	100	21	by	by	ADP
cet-1007	100	22	yeast	yeast	NOUN
cet-1007	100	23	.	.	PUNCT
cet-1007	101	1	in	in	ADP
cet-1007	101	2	summary	summary	NOUN
cet-1007	101	3	,	,	PUNCT
cet-1007	101	4	the	the	DET
cet-1007	101	5	apparent	apparent	ADJ
cet-1007	101	6	changes	change	NOUN
cet-1007	101	7	take	take	VERB
cet-1007	101	8	place	place	NOUN
cet-1007	101	9	in	in	ADP
cet-1007	101	10	the	the	DET
cet-1007	101	11	contents	content	NOUN
cet-1007	101	12	of	of	ADP
cet-1007	101	13	alkaloids	alkaloid	NOUN
cet-1007	101	14	of	of	ADP
cet-1007	101	15	aconitum	aconitum	NOUN
cet-1007	101	16	after	after	ADP
cet-1007	101	17	fermentation	fermentation	NOUN
cet-1007	101	18	by	by	ADP
cet-1007	101	19	yeast	yeast	NOUN
cet-1007	101	20	.	.	PUNCT
cet-1007	102	1	in	in	ADP
cet-1007	102	2	the	the	DET
cet-1007	102	3	extract	extract	NOUN
cet-1007	102	4	of	of	ADP
cet-1007	102	5	yeast	yeast	NOUN
cet-1007	102	6	-	-	PUNCT
cet-1007	102	7	fermented	ferment	VERB
cet-1007	102	8	aconitum	aconitum	NOUN
cet-1007	102	9	,	,	PUNCT
cet-1007	102	10	hypaconitine	hypaconitine	NOUN
cet-1007	102	11	decreases	decrease	NOUN
cet-1007	102	12	and	and	CCONJ
cet-1007	102	13	songorine	songorine	NOUN
cet-1007	102	14	increases	increase	NOUN
cet-1007	102	15	relatively	relatively	ADV
cet-1007	102	16	.	.	PUNCT
cet-1007	103	1	the	the	DET
cet-1007	103	2	variants	variant	NOUN
cet-1007	103	3	cause	cause	VERB
cet-1007	103	4	a	a	DET
cet-1007	103	5	slight	slight	ADJ
cet-1007	103	6	weakness	weakness	NOUN
cet-1007	103	7	in	in	ADP
cet-1007	103	8	analgesic	analgesic	ADJ
cet-1007	103	9	effect	effect	NOUN
cet-1007	103	10	of	of	ADP
cet-1007	103	11	yeast	yeast	NOUN
cet-1007	103	12	-	-	PUNCT
cet-1007	103	13	fermented	ferment	VERB
cet-1007	103	14	aconitum	aconitum	NOUN
cet-1007	103	15	,	,	PUNCT
cet-1007	103	16	but	but	CCONJ
cet-1007	103	17	these	these	PRON
cet-1007	103	18	lead	lead	VERB
cet-1007	103	19	to	to	ADP
cet-1007	103	20	a	a	DET
cet-1007	103	21	significant	significant	ADJ
cet-1007	103	22	reduction	reduction	NOUN
cet-1007	103	23	of	of	ADP
cet-1007	103	24	toxicity	toxicity	NOUN
cet-1007	103	25	of	of	ADP
cet-1007	103	26	yeast	yeast	NOUN
cet-1007	103	27	-	-	PUNCT
cet-1007	103	28	fermented	ferment	VERB
cet-1007	103	29	aconitum	aconitum	NOUN
cet-1007	103	30	.	.	PUNCT
cet-1007	104	1	yeast	yeast	NOUN
cet-1007	104	2	-	-	PUNCT
cet-1007	104	3	fermented	ferment	VERB
cet-1007	104	4	aconitum	aconitum	NOUN
cet-1007	104	5	has	have	VERB
cet-1007	104	6	a	a	DET
cet-1007	104	7	greater	great	ADJ
cet-1007	104	8	therapeutic	therapeutic	ADJ
cet-1007	104	9	efficacy	efficacy	NOUN
cet-1007	104	10	than	than	ADP
cet-1007	104	11	original	original	ADJ
cet-1007	104	12	aconitum	aconitum	NOUN
cet-1007	104	13	.	.	PUNCT
cet-1007	105	1	this	this	DET
cet-1007	105	2	discovery	discovery	NOUN
cet-1007	105	3	may	may	AUX
cet-1007	105	4	provide	provide	VERB
cet-1007	105	5	a	a	DET
cet-1007	105	6	basis	basis	NOUN
cet-1007	105	7	for	for	ADP
cet-1007	105	8	developing	develop	VERB
cet-1007	105	9	new	new	ADJ
cet-1007	105	10	analgesic	analgesic	ADJ
cet-1007	105	11	agents	agent	NOUN
cet-1007	105	12	.	.	PUNCT
cet-1007	106	1	table	table	NOUN
cet-1007	106	2	2	2	NUM
cet-1007	106	3	:	:	PUNCT
cet-1007	106	4	effects	effect	NOUN
cet-1007	106	5	of	of	ADP
cet-1007	106	6	the	the	DET
cet-1007	106	7	chloroform	chloroform	NOUN
cet-1007	106	8	extract	extract	NOUN
cet-1007	106	9	of	of	ADP
cet-1007	106	10	aconitum	aconitum	ADJ
cet-1007	106	11	and	and	CCONJ
cet-1007	106	12	yeast	yeast	NOUN
cet-1007	106	13	-	-	PUNCT
cet-1007	106	14	fermented	ferment	VERB
cet-1007	106	15	aconitum	aconitum	NOUN
cet-1007	106	16	on	on	ADP
cet-1007	106	17	the	the	DET
cet-1007	106	18	tail	tail	NOUN
cet-1007	106	19	clip	clip	NOUN
cet-1007	106	20	test	test	NOUN
cet-1007	106	21	in	in	ADP
cet-1007	106	22	mice	mouse	NOUN
cet-1007	106	23	group	group	NOUN
cet-1007	106	24	(	(	PUNCT
cet-1007	106	25	n=10	n=10	NOUN
cet-1007	106	26	)	)	PUNCT
cet-1007	106	27	dose	dose	NOUN
cet-1007	106	28	(	(	PUNCT
cet-1007	106	29	mg	mg	PROPN
cet-1007	106	30	/	/	SYM
cet-1007	106	31	kg	kg	NOUN
cet-1007	106	32	)	)	PUNCT
cet-1007	106	33	analgesia	analgesia	NOUN
cet-1007	106	34	(	(	PUNCT
cet-1007	106	35	%	%	INTJ
cet-1007	106	36	)	)	PUNCT
cet-1007	106	37	15min	15min	NOUN
cet-1007	106	38	30min	30min	NOUN
cet-1007	106	39	45min	45min	PROPN
cet-1007	106	40	60min	60min	NOUN
cet-1007	106	41	saline	saline	NOUN
cet-1007	106	42	control	control	NOUN
cet-1007	106	43	0	0	NUM
cet-1007	106	44	0	0	NUM
cet-1007	106	45	0	0	NUM
cet-1007	106	46	0	0	NUM
cet-1007	107	1	0.10	0.10	NUM
cet-1007	107	2	10/20	10/20	NUM
cet-1007	107	3	10/20	10/20	NUM
cet-1007	107	4	10/20	10/20	NUM
cet-1007	107	5	10/20	10/20	NUM
cet-1007	107	6	0.17	0.17	NUM
cet-1007	107	7	20/40	20/40	NUM
cet-1007	107	8	20/40	20/40	NUM
cet-1007	107	9	20/40	20/40	NUM
cet-1007	107	10	20/40	20/40	NUM
cet-1007	107	11	yeast	yeast	NOUN
cet-1007	107	12	-	-	PUNCT
cet-1007	107	13	fermented	ferment	VERB
cet-1007	107	14	aconitum	aconitum	ADJ
cet-1007	107	15	/	/	SYM
cet-1007	107	16	aconitum	aconitum	ADJ
cet-1007	107	17	0.30	0.30	NUM
cet-1007	107	18	30/50	30/50	NUM
cet-1007	107	19	30/50	30/50	NUM
cet-1007	107	20	30/50	30/50	NUM
cet-1007	107	21	30/50	30/50	NUM
cet-1007	107	22	0.50	0.50	NUM
cet-1007	107	23	40/90	40/90	NUM
cet-1007	108	1	40/90	40/90	NUM
cet-1007	108	2	40/90	40/90	NUM
cet-1007	108	3	40/90	40/90	NUM
cet-1007	108	4	0.80	0.80	NUM
cet-1007	108	5	80/10080/100	80/10080/100	NUM
cet-1007	108	6	80/100	80/100	NUM
cet-1007	108	7	80/100	80/100	NUM
cet-1007	108	8	morphine	morphine	NOUN
cet-1007	108	9	10	10	NUM
cet-1007	108	10	100	100	NUM
cet-1007	108	11	100	100	NUM
cet-1007	108	12	100	100	NUM
cet-1007	108	13	100	100	NUM
cet-1007	108	14	*	*	PUNCT
cet-1007	108	15	at	at	ADP
cet-1007	108	16	the	the	DET
cet-1007	108	17	dose	dose	NOUN
cet-1007	108	18	of	of	ADP
cet-1007	108	19	0.80	0.80	NUM
cet-1007	108	20	mg	mg	PROPN
cet-1007	108	21	/	/	SYM
cet-1007	108	22	kg	kg	PROPN
cet-1007	108	23	,	,	PUNCT
cet-1007	108	24	one	one	NUM
cet-1007	108	25	mouse	mouse	NOUN
cet-1007	108	26	in	in	ADP
cet-1007	108	27	group	group	NOUN
cet-1007	108	28	of	of	ADP
cet-1007	108	29	aconitum	aconitum	PROPN
cet-1007	108	30	died	die	VERB
cet-1007	108	31	within	within	ADP
cet-1007	108	32	15	15	NUM
cet-1007	108	33	min	min	NOUN
cet-1007	108	34	.	.	NOUN
cet-1007	108	35	1253	1253	NUM
cet-1007	108	36	table	table	NOUN
cet-1007	108	37	3	3	NUM
cet-1007	108	38	:	:	PUNCT
cet-1007	108	39	death	death	NOUN
cet-1007	108	40	monitored	monitor	VERB
cet-1007	108	41	over	over	ADP
cet-1007	108	42	a	a	DET
cet-1007	108	43	period	period	NOUN
cet-1007	108	44	of	of	ADP
cet-1007	108	45	24	24	NUM
cet-1007	108	46	h	h	NOUN
cet-1007	108	47	after	after	SCONJ
cet-1007	108	48	the	the	DET
cet-1007	108	49	extracts	extract	NOUN
cet-1007	108	50	of	of	ADP
cet-1007	108	51	aconitum	aconitum	NOUN
cet-1007	108	52	are	be	AUX
cet-1007	108	53	intraperitoneally	intraperitoneally	ADV
cet-1007	108	54	administered	administer	VERB
cet-1007	108	55	to	to	PART
cet-1007	108	56	mice	mice	VERB
cet-1007	108	57	sample	sample	NOUN
cet-1007	108	58	number	number	NOUN
cet-1007	108	59	of	of	ADP
cet-1007	108	60	animal	animal	NOUN
cet-1007	108	61	(	(	PUNCT
cet-1007	108	62	n	n	CCONJ
cet-1007	108	63	)	)	PUNCT
cet-1007	108	64	dose	dose	NOUN
cet-1007	108	65	range	range	NOUN
cet-1007	108	66	tested	test	VERB
cet-1007	108	67	i.p	i.p	PROPN
cet-1007	108	68	.	.	PUNCT
cet-1007	109	1	(	(	PUNCT
cet-1007	109	2	mg	mg	PROPN
cet-1007	109	3	/	/	SYM
cet-1007	109	4	kg	kg	NOUN
cet-1007	109	5	)	)	PUNCT
cet-1007	109	6	highest	high	ADJ
cet-1007	109	7	dose	dose	VERB
cet-1007	109	8	without	without	ADP
cet-1007	109	9	lethality	lethality	NOUN
cet-1007	109	10	(	(	PUNCT
cet-1007	109	11	mg	mg	PROPN
cet-1007	109	12	/	/	SYM
cet-1007	109	13	kg	kg	NOUN
cet-1007	109	14	)	)	PUNCT
cet-1007	110	1	ld50	ld50	PROPN
cet-1007	110	2	value	value	NOUN
cet-1007	110	3	(	(	PUNCT
cet-1007	110	4	mg	mg	PROPN
cet-1007	110	5	/	/	SYM
cet-1007	110	6	kg	kg	NOUN
cet-1007	110	7	)	)	PUNCT
cet-1007	110	8	yeast	yeast	NOUN
cet-1007	110	9	-	-	PUNCT
cet-1007	110	10	fermented	ferment	VERB
cet-1007	110	11	aconitum	aconitum	NOUN
cet-1007	110	12	10	10	NUM
cet-1007	110	13	2.60	2.60	NUM
cet-1007	110	14	-	-	SYM
cet-1007	110	15	34.0	34.0	NUM
cet-1007	110	16	2.60	2.60	NUM
cet-1007	110	17	13.80±1.92	13.80±1.92	NUM
cet-1007	110	18	aconitum	aconitum	ADJ
cet-1007	110	19	10	10	NUM
cet-1007	110	20	0.54	0.54	NUM
cet-1007	110	21	-	-	SYM
cet-1007	110	22	4.1	4.1	NUM
cet-1007	110	23	0.54	0.54	NUM
cet-1007	110	24	1.44±0.07	1.44±0.07	NUM
cet-1007	110	25	*	*	ADJ
cet-1007	110	26	values	value	NOUN
cet-1007	110	27	represent	represent	VERB
cet-1007	110	28	means	mean	VERB
cet-1007	110	29	±	±	NUM
cet-1007	110	30	sem	sem	PROPN
cet-1007	110	31	acknowledgement	acknowledgement	NOUN
cet-1007	110	32	this	this	DET
cet-1007	110	33	work	work	NOUN
cet-1007	110	34	was	be	AUX
cet-1007	110	35	financially	financially	ADV
cet-1007	110	36	supported	support	VERB
cet-1007	110	37	by	by	ADP
cet-1007	110	38	natural	natural	ADJ
cet-1007	110	39	science	science	NOUN
cet-1007	110	40	and	and	CCONJ
cet-1007	110	41	technology	technology	NOUN
cet-1007	110	42	foundation	foundation	NOUN
cet-1007	110	43	of	of	ADP
cet-1007	110	44	guizhou	guizhou	PROPN
cet-1007	110	45	province	province	PROPN
cet-1007	110	46	,	,	PUNCT
cet-1007	110	47	china	china	PROPN
cet-1007	110	48	(	(	PUNCT
cet-1007	110	49	[	[	X
cet-1007	110	50	2010]2225	2010]2225	NUM
cet-1007	110	51	)	)	PUNCT
cet-1007	110	52	.	.	PUNCT
cet-1007	111	1	project	project	NOUN
cet-1007	111	2	supported	support	VERB
cet-1007	111	3	by	by	ADP
cet-1007	111	4	guizhou	guizhou	PROPN
cet-1007	111	5	province	province	PROPN
cet-1007	111	6	natural	natural	ADJ
cet-1007	111	7	science	science	NOUN
cet-1007	111	8	and	and	CCONJ
cet-1007	111	9	technology	technology	NOUN
cet-1007	111	10	fund	fund	NOUN
cet-1007	111	11	project	project	NOUN
cet-1007	111	12	(	(	PUNCT
cet-1007	111	13	[	[	X
cet-1007	111	14	2010]2225	2010]2225	NUM
cet-1007	111	15	)	)	PUNCT
cet-1007	111	16	.	.	PUNCT
cet-1007	112	1	reference	reference	PROPN
cet-1007	112	2	ameri	ameri	PROPN
cet-1007	112	3	a.	a.	PROPN
cet-1007	112	4	,	,	PUNCT
cet-1007	112	5	1998	1998	NUM
cet-1007	112	6	,	,	PUNCT
cet-1007	112	7	the	the	DET
cet-1007	112	8	effects	effect	NOUN
cet-1007	112	9	of	of	ADP
cet-1007	112	10	aconitum	aconitum	ADJ
cet-1007	112	11	alkaloids	alkaloid	NOUN
cet-1007	112	12	on	on	ADP
cet-1007	112	13	the	the	DET
cet-1007	112	14	central	central	ADJ
cet-1007	112	15	nervous	nervous	ADJ
cet-1007	112	16	system	system	NOUN
cet-1007	112	17	,	,	PUNCT
cet-1007	112	18	prog	prog	NOUN
cet-1007	112	19	,	,	PUNCT
cet-1007	112	20	neurobiol	neurobiol	PROPN
cet-1007	112	21	,	,	PUNCT
cet-1007	112	22	56	56	NUM
cet-1007	112	23	,	,	PUNCT
cet-1007	112	24	2	2	NUM
cet-1007	112	25	,	,	PUNCT
cet-1007	112	26	211235	211235	NUM
cet-1007	112	27	,	,	PUNCT
cet-1007	112	28	doi	doi	NOUN
cet-1007	112	29	:	:	PUNCT
cet-1007	112	30	10.1016	10.1016	NUM
cet-1007	112	31	/	/	SYM
cet-1007	112	32	s0301	s0301	PROPN
cet-1007	112	33	-	-	PUNCT
cet-1007	112	34	0082(98)00037	0082(98)00037	PROPN
cet-1007	112	35	-	-	PUNCT
cet-1007	112	36	9	9	NUM
cet-1007	112	37	bianchi	bianchi	NOUN
cet-1007	112	38	c.	c.	PROPN
cet-1007	112	39	,	,	PUNCT
cet-1007	112	40	franceschini	franceschini	PROPN
cet-1007	112	41	j.	j.	PROPN
cet-1007	112	42	,	,	PUNCT
cet-1007	112	43	1954	1954	NUM
cet-1007	112	44	,	,	PUNCT
cet-1007	112	45	experimental	experimental	ADJ
cet-1007	112	46	observations	observation	NOUN
cet-1007	112	47	on	on	ADP
cet-1007	112	48	haffner	haffner	NOUN
cet-1007	112	49	's	's	PART
cet-1007	112	50	method	method	NOUN
cet-1007	112	51	for	for	ADP
cet-1007	112	52	testing	test	VERB
cet-1007	112	53	analgesic	analgesic	ADJ
cet-1007	112	54	drugs	drug	NOUN
cet-1007	112	55	,	,	PUNCT
cet-1007	112	56	br	br	PROPN
cet-1007	112	57	j	j	PROPN
cet-1007	112	58	pharmacol	pharmacol	PROPN
cet-1007	112	59	chemother	chemother	PROPN
cet-1007	112	60	,	,	PUNCT
cet-1007	112	61	9(3	9(3	NUM
cet-1007	112	62	)	)	PUNCT
cet-1007	112	63	,	,	PUNCT
cet-1007	112	64	280	280	NUM
cet-1007	112	65	-	-	SYM
cet-1007	112	66	4	4	NUM
cet-1007	112	67	,	,	PUNCT
cet-1007	112	68	doi	doi	NOUN
cet-1007	112	69	:	:	PUNCT
cet-1007	112	70	10.1111	10.1111	NUM
cet-1007	112	71	/	/	SYM
cet-1007	112	72	j.1476	j.1476	NOUN
cet-1007	112	73	-	-	PUNCT
cet-1007	112	74	5381.1954.tb01681.x	5381.1954.tb01681.x	NUM
cet-1007	112	75	buschmann	buschmann	PROPN
cet-1007	112	76	h.	h.	PROPN
cet-1007	112	77	,	,	PUNCT
cet-1007	112	78	christoph	christoph	PROPN
cet-1007	112	79	t.	t.	PROPN
cet-1007	112	80	,	,	PUNCT
cet-1007	112	81	maul	maul	PROPN
cet-1007	112	82	c.	c.	PROPN
cet-1007	112	83	,	,	PUNCT
cet-1007	112	84	sundermann	sundermann	PROPN
cet-1007	112	85	b.	b.	PROPN
cet-1007	112	86	,	,	PUNCT
cet-1007	112	87	2004	2004	NUM
cet-1007	112	88	,	,	PUNCT
cet-1007	112	89	analgesics	analgesic	NOUN
cet-1007	112	90	:	:	PUNCT
cet-1007	112	91	from	from	ADP
cet-1007	112	92	chemistry	chemistry	NOUN
cet-1007	112	93	and	and	CCONJ
cet-1007	112	94	pharmacology	pharmacology	NOUN
cet-1007	112	95	to	to	ADP
cet-1007	112	96	clinical	clinical	ADJ
cet-1007	112	97	application	application	NOUN
cet-1007	112	98	,	,	PUNCT
cet-1007	112	99	journal	journal	NOUN
cet-1007	112	100	of	of	ADP
cet-1007	112	101	the	the	DET
cet-1007	112	102	national	national	PROPN
cet-1007	112	103	medical	medical	PROPN
cet-1007	112	104	association	association	PROPN
cet-1007	112	105	,	,	PUNCT
cet-1007	112	106	96(4	96(4	NOUN
cet-1007	112	107	)	)	PUNCT
cet-1007	112	108	,	,	PUNCT
cet-1007	112	109	567	567	NUM
cet-1007	112	110	.	.	PUNCT
cet-1007	113	1	chan	chan	PROPN
cet-1007	113	2	t.y	t.y	PROPN
cet-1007	113	3	.	.	PROPN
cet-1007	113	4	,	,	PUNCT
cet-1007	113	5	tomlinson	tomlinson	PROPN
cet-1007	113	6	b.	b.	PROPN
cet-1007	113	7	,	,	PUNCT
cet-1007	113	8	tse	tse	PROPN
cet-1007	113	9	l.k	l.k	PROPN
cet-1007	113	10	.	.	PROPN
cet-1007	113	11	,	,	PUNCT
cet-1007	113	12	chan	chan	PROPN
cet-1007	113	13	j.c	j.c	PROPN
cet-1007	113	14	.	.	PROPN
cet-1007	113	15	,	,	PUNCT
cet-1007	114	1	chan	chan	PROPN
cet-1007	114	2	w.w	w.w	PROPN
cet-1007	114	3	.	.	PROPN
cet-1007	114	4	,	,	PUNCT
cet-1007	114	5	critchley	critchley	PROPN
cet-1007	114	6	j.a	j.a	PROPN
cet-1007	114	7	.	.	PROPN
cet-1007	114	8	,	,	PUNCT
cet-1007	114	9	1994	1994	NUM
cet-1007	114	10	,	,	PUNCT
cet-1007	114	11	aconitine	aconitine	NOUN
cet-1007	114	12	poisoning	poisoning	NOUN
cet-1007	114	13	due	due	ADP
cet-1007	114	14	to	to	ADP
cet-1007	114	15	chinese	chinese	ADJ
cet-1007	114	16	herbal	herbal	ADJ
cet-1007	114	17	medicines	medicine	NOUN
cet-1007	114	18	:	:	PUNCT
cet-1007	114	19	a	a	DET
cet-1007	114	20	review	review	NOUN
cet-1007	114	21	,	,	PUNCT
cet-1007	114	22	vet	vet	NOUN
cet-1007	114	23	hum	hum	NOUN
cet-1007	114	24	toxicol	toxicol	PROPN
cet-1007	114	25	,	,	PUNCT
cet-1007	114	26	36(5	36(5	NUM
cet-1007	114	27	)	)	PUNCT
cet-1007	114	28	,	,	PUNCT
cet-1007	114	29	452	452	NUM
cet-1007	114	30	-	-	SYM
cet-1007	114	31	5	5	NUM
cet-1007	114	32	.	.	PUNCT
cet-1007	115	1	hamilton	hamilton	PROPN
cet-1007	115	2	m.a	m.a	PROPN
cet-1007	115	3	.	.	PROPN
cet-1007	115	4	,	,	PUNCT
cet-1007	115	5	russo	russo	PROPN
cet-1007	115	6	r.c	r.c	PROPN
cet-1007	115	7	.	.	PROPN
cet-1007	115	8	,	,	PUNCT
cet-1007	115	9	thurston	thurston	PROPN
cet-1007	115	10	r.v	r.v	PROPN
cet-1007	115	11	.	.	PROPN
cet-1007	115	12	,	,	PUNCT
cet-1007	115	13	1977	1977	NUM
cet-1007	115	14	,	,	PUNCT
cet-1007	115	15	trimmed	trim	VERB
cet-1007	115	16	spearman	spearman	NOUN
cet-1007	115	17	-	-	PUNCT
cet-1007	115	18	karber	karber	PROPN
cet-1007	115	19	method	method	NOUN
cet-1007	115	20	for	for	ADP
cet-1007	115	21	estimating	estimate	VERB
cet-1007	115	22	median	median	ADJ
cet-1007	115	23	lethal	lethal	ADJ
cet-1007	115	24	concentrations	concentration	NOUN
cet-1007	115	25	in	in	ADP
cet-1007	115	26	toxicity	toxicity	NOUN
cet-1007	115	27	bioassays	bioassay	NOUN
cet-1007	115	28	,	,	PUNCT
cet-1007	115	29	environ	environ	X
cet-1007	115	30	.	.	PUNCT
cet-1007	116	1	sci	sci	PROPN
cet-1007	116	2	.	.	PROPN
cet-1007	116	3	technol	technol	PROPN
cet-1007	116	4	,	,	PUNCT
cet-1007	116	5	11(7	11(7	NUM
cet-1007	116	6	)	)	PUNCT
cet-1007	116	7	,	,	PUNCT
cet-1007	116	8	714	714	NUM
cet-1007	116	9	-	-	SYM
cet-1007	116	10	19	19	NUM
cet-1007	116	11	.	.	PUNCT
cet-1007	117	1	hikino	hikino	PROPN
cet-1007	117	2	h.	h.	PROPN
cet-1007	117	3	,	,	PUNCT
cet-1007	117	4	ito	ito	PROPN
cet-1007	117	5	t.	t.	PROPN
cet-1007	117	6	,	,	PUNCT
cet-1007	117	7	yamada	yamada	PROPN
cet-1007	117	8	c.	c.	PROPN
cet-1007	117	9	,	,	PUNCT
cet-1007	117	10	sato	sato	PROPN
cet-1007	117	11	h.	h.	PROPN
cet-1007	117	12	,	,	PUNCT
cet-1007	117	13	konno	konno	PROPN
cet-1007	117	14	c.	c.	PROPN
cet-1007	117	15	,	,	PUNCT
cet-1007	117	16	ohizumi	ohizumi	PROPN
cet-1007	117	17	y.	y.	PROPN
cet-1007	117	18	,	,	PUNCT
cet-1007	117	19	1979	1979	NUM
cet-1007	117	20	,	,	PUNCT
cet-1007	117	21	analgesic	analgesic	ADJ
cet-1007	117	22	principles	principle	NOUN
cet-1007	117	23	of	of	ADP
cet-1007	117	24	aconitum	aconitum	ADJ
cet-1007	117	25	roots	root	NOUN
cet-1007	117	26	,	,	PUNCT
cet-1007	117	27	j.phrama.dyn	j.phrama.dyn	NOUN
cet-1007	117	28	,	,	PUNCT
cet-1007	117	29	2(2	2(2	NUM
cet-1007	117	30	)	)	PUNCT
cet-1007	117	31	,	,	PUNCT
cet-1007	117	32	78	78	NUM
cet-1007	117	33	-	-	SYM
cet-1007	117	34	83	83	NUM
cet-1007	117	35	,	,	PUNCT
cet-1007	117	36	doi	doi	NOUN
cet-1007	117	37	:	:	PUNCT
cet-1007	117	38	10.1248	10.1248	NUM
cet-1007	117	39	/	/	SYM
cet-1007	117	40	bpb1978.2.78	bpb1978.2.78	PROPN
cet-1007	117	41	nikolova	nikolova	PROPN
cet-1007	118	1	p.	p.	NOUN
cet-1007	118	2	,	,	PUNCT
cet-1007	118	3	ward	ward	PROPN
cet-1007	118	4	o.p	o.p	PROPN
cet-1007	118	5	.	.	PROPN
cet-1007	118	6	,	,	PUNCT
cet-1007	118	7	1992	1992	NUM
cet-1007	118	8	,	,	PUNCT
cet-1007	118	9	whole	whole	ADJ
cet-1007	118	10	cell	cell	NOUN
cet-1007	118	11	yeast	yeast	NOUN
cet-1007	118	12	biotransformations	biotransformation	NOUN
cet-1007	118	13	in	in	ADP
cet-1007	118	14	two	two	NUM
cet-1007	118	15	-	-	PUNCT
cet-1007	118	16	phase	phase	NOUN
cet-1007	118	17	systems	system	NOUN
cet-1007	118	18	:	:	PUNCT
cet-1007	118	19	effect	effect	NOUN
cet-1007	118	20	of	of	ADP
cet-1007	118	21	solvent	solvent	NOUN
cet-1007	118	22	on	on	ADP
cet-1007	118	23	product	product	NOUN
cet-1007	118	24	formation	formation	NOUN
cet-1007	118	25	and	and	CCONJ
cet-1007	118	26	cell	cell	NOUN
cet-1007	118	27	structure	structure	NOUN
cet-1007	118	28	,	,	PUNCT
cet-1007	118	29	j.	j.	PROPN
cet-1007	118	30	ind	ind	PROPN
cet-1007	118	31	.	.	PUNCT
cet-1007	119	1	microbio	microbio	PROPN
cet-1007	119	2	,	,	PUNCT
cet-1007	119	3	10(3	10(3	NUM
cet-1007	119	4	-	-	SYM
cet-1007	119	5	4	4	NUM
cet-1007	119	6	)	)	PUNCT
cet-1007	119	7	,	,	PUNCT
cet-1007	119	8	169	169	NUM
cet-1007	119	9	-	-	SYM
cet-1007	119	10	77	77	NUM
cet-1007	119	11	,	,	PUNCT
cet-1007	119	12	doi	doi	NOUN
cet-1007	119	13	:	:	PUNCT
cet-1007	119	14	10.1007	10.1007	NUM
cet-1007	119	15	/	/	SYM
cet-1007	119	16	bf01569762	bf01569762	NOUN
cet-1007	119	17	pereira	pereira	PROPN
cet-1007	119	18	r.d.s	r.d.s	PROPN
cet-1007	119	19	.	.	PROPN
cet-1007	119	20	,	,	PUNCT
cet-1007	119	21	1998	1998	NUM
cet-1007	119	22	,	,	PUNCT
cet-1007	119	23	the	the	DET
cet-1007	119	24	use	use	NOUN
cet-1007	119	25	of	of	ADP
cet-1007	119	26	baker	baker	NOUN
cet-1007	119	27	's	's	PART
cet-1007	119	28	yeast	yeast	NOUN
cet-1007	119	29	in	in	ADP
cet-1007	119	30	the	the	DET
cet-1007	119	31	generation	generation	NOUN
cet-1007	119	32	of	of	ADP
cet-1007	119	33	asymmetric	asymmetric	ADJ
cet-1007	119	34	centers	center	NOUN
cet-1007	119	35	to	to	PART
cet-1007	119	36	produce	produce	VERB
cet-1007	119	37	chiral	chiral	ADJ
cet-1007	119	38	drugs	drug	NOUN
cet-1007	119	39	and	and	CCONJ
cet-1007	119	40	others	other	NOUN
cet-1007	119	41	compounds	compound	NOUN
cet-1007	119	42	,	,	PUNCT
cet-1007	119	43	crit	crit	PROPN
cet-1007	119	44	rev	rev	PROPN
cet-1007	119	45	biotechnol	biotechnol	NOUN
cet-1007	119	46	,	,	PUNCT
cet-1007	119	47	18(1	18(1	NUM
cet-1007	119	48	)	)	PUNCT
cet-1007	119	49	,	,	PUNCT
cet-1007	119	50	25	25	NUM
cet-1007	119	51	-	-	SYM
cet-1007	119	52	83	83	NUM
cet-1007	119	53	,	,	PUNCT
cet-1007	119	54	doi	doi	NOUN
cet-1007	119	55	:	:	PUNCT
cet-1007	119	56	10.1080/0738	10.1080/0738	NUM
cet-1007	119	57	-	-	SYM
cet-1007	119	58	859891224211	859891224211	NUM
cet-1007	119	59	rathbone	rathbone	PROPN
cet-1007	119	60	d.a	d.a	PROPN
cet-1007	119	61	.	.	PROPN
cet-1007	119	62	,	,	PUNCT
cet-1007	119	63	bruce	bruce	PROPN
cet-1007	119	64	n.c	n.c	PROPN
cet-1007	119	65	.	.	PROPN
cet-1007	119	66	,	,	PUNCT
cet-1007	119	67	2002	2002	NUM
cet-1007	119	68	,	,	PUNCT
cet-1007	119	69	microbial	microbial	ADJ
cet-1007	119	70	transformation	transformation	NOUN
cet-1007	119	71	of	of	ADP
cet-1007	119	72	alkaloids	alkaloid	NOUN
cet-1007	119	73	,	,	PUNCT
cet-1007	119	74	curr	curr	PROPN
cet-1007	119	75	.	.	PUNCT
cet-1007	120	1	opin	opin	NOUN
cet-1007	120	2	.	.	PUNCT
cet-1007	121	1	microbiol	microbiol	PROPN
cet-1007	121	2	.	.	PUNCT
cet-1007	122	1	5(3	5(3	NUM
cet-1007	122	2	)	)	PUNCT
cet-1007	122	3	,	,	PUNCT
cet-1007	122	4	274	274	NUM
cet-1007	122	5	-	-	SYM
cet-1007	122	6	281	281	NUM
cet-1007	122	7	.	.	PUNCT
cet-1007	123	1	venisetty	venisetty	PROPN
cet-1007	123	2	r.k	r.k	PROPN
cet-1007	123	3	.	.	PROPN
cet-1007	123	4	,	,	PUNCT
cet-1007	123	5	ciddi	ciddi	ADJ
cet-1007	123	6	v.	v.	ADP
cet-1007	123	7	,	,	PUNCT
cet-1007	123	8	2003	2003	NUM
cet-1007	123	9	,	,	PUNCT
cet-1007	123	10	application	application	NOUN
cet-1007	123	11	of	of	ADP
cet-1007	123	12	microbial	microbial	ADJ
cet-1007	123	13	biotransformation	biotransformation	NOUN
cet-1007	123	14	for	for	ADP
cet-1007	123	15	the	the	DET
cet-1007	123	16	new	new	ADJ
cet-1007	123	17	drug	drug	NOUN
cet-1007	123	18	discovery	discovery	NOUN
cet-1007	123	19	using	use	VERB
cet-1007	123	20	natural	natural	ADJ
cet-1007	123	21	drugs	drug	NOUN
cet-1007	123	22	as	as	ADP
cet-1007	123	23	substrates	substrate	NOUN
cet-1007	123	24	,	,	PUNCT
cet-1007	124	1	curr	curr	PROPN
cet-1007	124	2	.	.	PUNCT
cet-1007	124	3	pharm	pharm	PROPN
cet-1007	124	4	.	.	PUNCT
cet-1007	125	1	biotechnol	biotechnol	PROPN
cet-1007	125	2	,	,	PUNCT
cet-1007	125	3	4(3	4(3	NUM
cet-1007	125	4	)	)	PUNCT
cet-1007	125	5	,	,	PUNCT
cet-1007	125	6	153	153	NUM
cet-1007	125	7	-	-	SYM
cet-1007	125	8	167	167	NUM
cet-1007	125	9	,	,	PUNCT
cet-1007	125	10	doi	doi	NOUN
cet-1007	125	11	:	:	PUNCT
cet-1007	125	12	10.2174/1389201033489847	10.2174/1389201033489847	NUM
cet-1007	125	13	walker	walker	PROPN
cet-1007	125	14	g.	g.	PROPN
cet-1007	125	15	,	,	PUNCT
cet-1007	125	16	1998	1998	NUM
cet-1007	125	17	,	,	PUNCT
cet-1007	125	18	yeast	yeast	NOUN
cet-1007	125	19	physiology	physiology	NOUN
cet-1007	125	20	and	and	CCONJ
cet-1007	125	21	biotechnology	biotechnology	NOUN
cet-1007	125	22	,	,	PUNCT
cet-1007	125	23	wiley	wiley	NOUN
cet-1007	125	24	,	,	PUNCT
cet-1007	125	25	368	368	NUM
cet-1007	125	26	.	.	PUNCT
cet-1007	126	1	zhao	zhao	PROPN
cet-1007	126	2	q.	q.	PROPN
cet-1007	126	3	,	,	PUNCT
cet-1007	126	4	wang	wang	PROPN
cet-1007	126	5	t.p	t.p	PROPN
cet-1007	126	6	.	.	PROPN
cet-1007	126	7	,	,	PUNCT
cet-1007	126	8	yuan	yuan	PROPN
cet-1007	126	9	y.j	y.j	PROPN
cet-1007	126	10	.	.	PROPN
cet-1007	126	11	,	,	PUNCT
cet-1007	126	12	2012	2012	NUM
cet-1007	126	13	,	,	PUNCT
cet-1007	126	14	optimization	optimization	NOUN
cet-1007	126	15	of	of	ADP
cet-1007	126	16	si	si	PROPN
cet-1007	126	17	jiu	jiu	PROPN
cet-1007	126	18	yu	yu	PROPN
cet-1007	126	19	,	,	PUNCT
cet-1007	126	20	the	the	DET
cet-1007	126	21	extraction	extraction	NOUN
cet-1007	126	22	process	process	NOUN
cet-1007	126	23	of	of	ADP
cet-1007	126	24	alkaloids	alkaloid	NOUN
cet-1007	126	25	from	from	ADP
cet-1007	126	26	favus	favus	PROPN
cet-1007	126	27	of	of	ADP
cet-1007	126	28	the	the	DET
cet-1007	126	29	scalp	scalp	NOUN
cet-1007	126	30	and	and	CCONJ
cet-1007	126	31	the	the	DET
cet-1007	126	32	antibacterial	antibacterial	ADJ
cet-1007	126	33	activity	activity	NOUN
cet-1007	126	34	,	,	PUNCT
cet-1007	126	35	acta	acta	PROPN
cet-1007	126	36	prataculturae	prataculturae	PROPN
cet-1007	126	37	sinica	sinica	PROPN
cet-1007	126	38	response	response	PROPN
cet-1007	126	39	surface	surface	NOUN
cet-1007	126	40	method	method	NOUN
cet-1007	126	41	,	,	PUNCT
cet-1007	126	42	21(4	21(4	NUM
cet-1007	126	43	)	)	PUNCT
cet-1007	126	44	,	,	PUNCT
cet-1007	126	45	20621	20621	NUM
cet-1007	126	46	.	.	PUNCT
cet-1007	127	1	1254	1254	NUM