id	sid	tid	token	lemma	pos
cet-14807	1	1	doi	doi	NOUN
cet-14807	1	2	:	:	PUNCT
cet-14807	1	3	10.3303	10.3303	NUM
cet-14807	1	4	/	/	SYM
cet-14807	1	5	cet24113012	cet24113012	NOUN
cet-14807	1	6	paper	paper	NOUN
cet-14807	1	7	received	receive	VERB
cet-14807	1	8	:	:	PUNCT
cet-14807	1	9	1	1	NUM
cet-14807	1	10	may	may	PROPN
cet-14807	1	11	2024	2024	NUM
cet-14807	1	12	;	;	PUNCT
cet-14807	1	13	revised	revise	VERB
cet-14807	1	14	:	:	PUNCT
cet-14807	1	15	16	16	NUM
cet-14807	1	16	july	july	PROPN
cet-14807	1	17	2024	2024	NUM
cet-14807	1	18	;	;	PUNCT
cet-14807	1	19	accepted	accept	VERB
cet-14807	1	20	:	:	PUNCT
cet-14807	1	21	8	8	NUM
cet-14807	1	22	november	november	NOUN
cet-14807	1	23	2024	2024	NUM
cet-14807	1	24	please	please	INTJ
cet-14807	1	25	cite	cite	VERB
cet-14807	1	26	this	this	DET
cet-14807	1	27	article	article	NOUN
cet-14807	1	28	as	as	ADP
cet-14807	1	29	:	:	PUNCT
cet-14807	1	30	monterola	monterola	PROPN
cet-14807	1	31	jr	jr	PROPN
cet-14807	1	32	c.p	c.p	PROPN
cet-14807	1	33	.	.	PROPN
cet-14807	1	34	,	,	PUNCT
cet-14807	1	35	espiel	espiel	PROPN
cet-14807	1	36	j.f	j.f	PROPN
cet-14807	1	37	.	.	PROPN
cet-14807	1	38	,	,	PUNCT
cet-14807	1	39	romero	romero	PROPN
cet-14807	1	40	j.r.r	j.r.r	PROPN
cet-14807	1	41	.	.	PROPN
cet-14807	1	42	,	,	PUNCT
cet-14807	1	43	pañe	pañe	PROPN
cet-14807	1	44	r.d.j	r.d.j	NOUN
cet-14807	1	45	.	.	PROPN
cet-14807	1	46	,	,	PUNCT
cet-14807	1	47	2024	2024	NUM
cet-14807	1	48	,	,	PUNCT
cet-14807	1	49	molecular	molecular	ADJ
cet-14807	1	50	docking	docking	NOUN
cet-14807	1	51	of	of	ADP
cet-14807	1	52	bioactive	bioactive	ADJ
cet-14807	1	53	components	component	NOUN
cet-14807	1	54	of	of	ADP
cet-14807	1	55	tawa	tawa	PROPN
cet-14807	1	56	-	-	PUNCT
cet-14807	1	57	tawa	tawa	PROPN
cet-14807	1	58	(	(	PUNCT
cet-14807	1	59	euphorbia	euphorbia	PROPN
cet-14807	1	60	hirta	hirta	PROPN
cet-14807	1	61	l.	l.	PROPN
cet-14807	1	62	)	)	PUNCT
cet-14807	1	63	leaves	leave	VERB
cet-14807	1	64	as	as	ADP
cet-14807	1	65	inhibitor	inhibitor	NOUN
cet-14807	1	66	against	against	ADP
cet-14807	1	67	the	the	DET
cet-14807	1	68	ns2b	ns2b	NOUN
cet-14807	1	69	-	-	PUNCT
cet-14807	1	70	ns3	ns3	NOUN
cet-14807	1	71	protease	protease	NOUN
cet-14807	1	72	of	of	ADP
cet-14807	1	73	denv-2	denv-2	PROPN
cet-14807	1	74	,	,	PUNCT
cet-14807	1	75	chemical	chemical	ADJ
cet-14807	1	76	engineering	engineering	NOUN
cet-14807	1	77	transactions	transaction	NOUN
cet-14807	1	78	,	,	PUNCT
cet-14807	1	79	113	113	NUM
cet-14807	1	80	,	,	PUNCT
cet-14807	1	81	6772	6772	NUM
cet-14807	1	82	doi:10.3303	doi:10.3303	NOUN
cet-14807	1	83	/	/	SYM
cet-14807	1	84	cet24113012	cet24113012	NOUN
cet-14807	1	85	chemical	chemical	NOUN
cet-14807	1	86	engineering	engineering	NOUN
cet-14807	1	87	transactions	transaction	NOUN
cet-14807	1	88	vol	vol	NOUN
cet-14807	1	89	.	.	PROPN
cet-14807	1	90	113	113	NUM
cet-14807	1	91	,	,	PUNCT
cet-14807	1	92	2024	2024	NUM
cet-14807	1	93	a	a	DET
cet-14807	1	94	publication	publication	NOUN
cet-14807	1	95	of	of	ADP
cet-14807	1	96	the	the	DET
cet-14807	1	97	italian	italian	ADJ
cet-14807	1	98	association	association	NOUN
cet-14807	1	99	of	of	ADP
cet-14807	1	100	chemical	chemical	PROPN
cet-14807	1	101	engineering	engineering	NOUN
cet-14807	1	102	online	online	ADV
cet-14807	1	103	at	at	ADP
cet-14807	1	104	www.cetjournal.it	www.cetjournal.it	PROPN
cet-14807	1	105	guest	guest	NOUN
cet-14807	1	106	editors	editor	NOUN
cet-14807	1	107	:	:	PUNCT
cet-14807	1	108	jeng	jeng	PROPN
cet-14807	1	109	shiun	shiun	PROPN
cet-14807	1	110	lim	lim	PROPN
cet-14807	1	111	,	,	PUNCT
cet-14807	1	112	bohong	bohong	PROPN
cet-14807	1	113	wang	wang	PROPN
cet-14807	1	114	,	,	PUNCT
cet-14807	1	115	guo	guo	PROPN
cet-14807	1	116	ren	ren	PROPN
cet-14807	1	117	mong	mong	PROPN
cet-14807	1	118	,	,	PUNCT
cet-14807	1	119	petar	petar	PROPN
cet-14807	1	120	s.	s.	PROPN
cet-14807	1	121	varbanov	varbanov	PROPN
cet-14807	1	122	copyright	copyright	NOUN
cet-14807	1	123	©	©	PROPN
cet-14807	1	124	2024	2024	NUM
cet-14807	1	125	,	,	PUNCT
cet-14807	1	126	aidic	aidic	ADJ
cet-14807	1	127	servizi	servizi	PROPN
cet-14807	1	128	s.r.l	s.r.l	NOUN
cet-14807	1	129	.	.	PUNCT
cet-14807	2	1	isbn	isbn	PROPN
cet-14807	2	2	979	979	NUM
cet-14807	2	3	-	-	SYM
cet-14807	2	4	12	12	NUM
cet-14807	2	5	-	-	PUNCT
cet-14807	2	6	81206	81206	NUM
cet-14807	2	7	-	-	SYM
cet-14807	2	8	14	14	NUM
cet-14807	2	9	-	-	SYM
cet-14807	2	10	4	4	NUM
cet-14807	2	11	;	;	PUNCT
cet-14807	2	12	issn	issn	PROPN
cet-14807	2	13	2283	2283	NUM
cet-14807	2	14	-	-	SYM
cet-14807	2	15	9216	9216	NUM
cet-14807	2	16	molecular	molecular	ADJ
cet-14807	2	17	docking	docking	NOUN
cet-14807	2	18	of	of	ADP
cet-14807	2	19	bioactive	bioactive	ADJ
cet-14807	2	20	components	component	NOUN
cet-14807	2	21	of	of	ADP
cet-14807	2	22	tawa	tawa	PROPN
cet-14807	2	23	-	-	PUNCT
cet-14807	2	24	tawa	tawa	PROPN
cet-14807	2	25	(	(	PUNCT
cet-14807	2	26	euphorbia	euphorbia	PROPN
cet-14807	2	27	hirta	hirta	PROPN
cet-14807	2	28	l.	l.	PROPN
cet-14807	2	29	)	)	PUNCT
cet-14807	2	30	leaves	leave	VERB
cet-14807	2	31	as	as	ADP
cet-14807	2	32	inhibitor	inhibitor	NOUN
cet-14807	2	33	against	against	ADP
cet-14807	2	34	the	the	DET
cet-14807	2	35	ns2b	ns2b	NOUN
cet-14807	2	36	-	-	PUNCT
cet-14807	2	37	ns3	ns3	NOUN
cet-14807	2	38	protease	protease	NOUN
cet-14807	2	39	of	of	ADP
cet-14807	2	40	denv-2	denv-2	PROPN
cet-14807	2	41	conrado	conrado	PROPN
cet-14807	3	1	p.	p.	PROPN
cet-14807	3	2	monterola	monterola	PROPN
cet-14807	4	1	jr	jr	PROPN
cet-14807	4	2	.	.	PROPN
cet-14807	4	3	*	*	PROPN
cet-14807	4	4	,	,	PUNCT
cet-14807	4	5	jericho	jericho	PROPN
cet-14807	4	6	f.	f.	PROPN
cet-14807	4	7	espiel	espiel	PROPN
cet-14807	4	8	,	,	PUNCT
cet-14807	4	9	jhon	jhon	PROPN
cet-14807	4	10	russell	russell	PROPN
cet-14807	4	11	r.	r.	PROPN
cet-14807	4	12	romero	romero	PROPN
cet-14807	4	13	,	,	PUNCT
cet-14807	4	14	romano	romano	NOUN
cet-14807	4	15	danniel	danniel	NOUN
cet-14807	4	16	j.	j.	PROPN
cet-14807	4	17	pañe	pañe	PROPN
cet-14807	4	18	mapũa	mapũa	PROPN
cet-14807	4	19	malayan	malayan	PROPN
cet-14807	4	20	colleges	colleges	PROPN
cet-14807	4	21	laguna	laguna	PROPN
cet-14807	4	22	,	,	PUNCT
cet-14807	4	23	cabuyao	cabuyao	PROPN
cet-14807	4	24	philippines	philippine	NOUN
cet-14807	4	25	cpmonterola@mcl.edu.ph	cpmonterola@mcl.edu.ph	ADJ
cet-14807	4	26	from	from	ADP
cet-14807	4	27	january	january	PROPN
cet-14807	4	28	1	1	NUM
cet-14807	4	29	to	to	ADP
cet-14807	4	30	august	august	PROPN
cet-14807	4	31	20	20	NUM
cet-14807	4	32	,	,	PUNCT
cet-14807	4	33	2022	2022	NUM
cet-14807	4	34	,	,	PUNCT
cet-14807	4	35	the	the	DET
cet-14807	4	36	philippines	philippine	NOUN
cet-14807	4	37	recorded	record	VERB
cet-14807	4	38	128,346	128,346	NUM
cet-14807	4	39	dengue	dengue	NOUN
cet-14807	4	40	cases	case	NOUN
cet-14807	4	41	and	and	CCONJ
cet-14807	4	42	422	422	NUM
cet-14807	4	43	deaths	death	NOUN
cet-14807	4	44	,	,	PUNCT
cet-14807	4	45	a	a	DET
cet-14807	4	46	significant	significant	ADJ
cet-14807	4	47	increase	increase	NOUN
cet-14807	4	48	from	from	ADP
cet-14807	4	49	the	the	DET
cet-14807	4	50	50,982	50,982	NUM
cet-14807	4	51	cases	case	NOUN
cet-14807	4	52	in	in	ADP
cet-14807	4	53	2021	2021	NUM
cet-14807	4	54	,	,	PUNCT
cet-14807	4	55	according	accord	VERB
cet-14807	4	56	to	to	ADP
cet-14807	4	57	the	the	DET
cet-14807	4	58	world	world	PROPN
cet-14807	4	59	health	health	NOUN
cet-14807	4	60	organization	organization	NOUN
cet-14807	4	61	.	.	PUNCT
cet-14807	5	1	this	this	DET
cet-14807	5	2	study	study	NOUN
cet-14807	5	3	aims	aim	VERB
cet-14807	5	4	to	to	PART
cet-14807	5	5	simulate	simulate	VERB
cet-14807	5	6	the	the	DET
cet-14807	5	7	inhibition	inhibition	NOUN
cet-14807	5	8	of	of	ADP
cet-14807	5	9	the	the	DET
cet-14807	5	10	ns2b	ns2b	NOUN
cet-14807	5	11	-	-	PUNCT
cet-14807	5	12	ns3	ns3	NOUN
cet-14807	5	13	protease	protease	NOUN
cet-14807	5	14	of	of	ADP
cet-14807	5	15	denv-2	denv-2	PROPN
cet-14807	5	16	(	(	PUNCT
cet-14807	5	17	pdb	pdb	PROPN
cet-14807	5	18	code	code	PROPN
cet-14807	5	19	:	:	PUNCT
cet-14807	5	20	2fom	2fom	NOUN
cet-14807	5	21	)	)	PUNCT
cet-14807	5	22	using	use	VERB
cet-14807	5	23	bioactive	bioactive	ADJ
cet-14807	5	24	compounds	compound	NOUN
cet-14807	5	25	from	from	ADP
cet-14807	5	26	tawa	tawa	NOUN
cet-14807	5	27	-	-	PUNCT
cet-14807	5	28	tawa	tawa	PROPN
cet-14807	5	29	and	and	CCONJ
cet-14807	5	30	analyzing	analyze	VERB
cet-14807	5	31	the	the	DET
cet-14807	5	32	toxicity	toxicity	NOUN
cet-14807	5	33	properties	property	NOUN
cet-14807	5	34	of	of	ADP
cet-14807	5	35	these	these	DET
cet-14807	5	36	compounds	compound	NOUN
cet-14807	5	37	.	.	PUNCT
cet-14807	6	1	the	the	DET
cet-14807	6	2	methods	method	NOUN
cet-14807	6	3	include	include	VERB
cet-14807	6	4	autodock	autodock	NOUN
cet-14807	6	5	vina	vina	NOUN
cet-14807	6	6	for	for	ADP
cet-14807	6	7	molecular	molecular	ADJ
cet-14807	6	8	docking	docking	NOUN
cet-14807	6	9	,	,	PUNCT
cet-14807	6	10	biovia	biovia	NOUN
cet-14807	6	11	for	for	ADP
cet-14807	6	12	interaction	interaction	NOUN
cet-14807	6	13	visualization	visualization	NOUN
cet-14807	6	14	,	,	PUNCT
cet-14807	6	15	swissadme	swissadme	NOUN
cet-14807	6	16	for	for	ADP
cet-14807	6	17	predicting	predict	VERB
cet-14807	6	18	oral	oral	ADJ
cet-14807	6	19	bioavailability	bioavailability	NOUN
cet-14807	6	20	via	via	ADP
cet-14807	6	21	lipinski	lipinski	PROPN
cet-14807	6	22	analysis	analysis	NOUN
cet-14807	6	23	,	,	PUNCT
cet-14807	6	24	and	and	CCONJ
cet-14807	6	25	admetsar	admetsar	VERB
cet-14807	6	26	for	for	ADP
cet-14807	6	27	assessing	assess	VERB
cet-14807	6	28	blood	blood	NOUN
cet-14807	6	29	-	-	PUNCT
cet-14807	6	30	brain	brain	NOUN
cet-14807	6	31	barrier	barrier	NOUN
cet-14807	6	32	permeability	permeability	NOUN
cet-14807	6	33	and	and	CCONJ
cet-14807	6	34	toxicity	toxicity	NOUN
cet-14807	6	35	.	.	PUNCT
cet-14807	7	1	ribavirin	ribavirin	NOUN
cet-14807	7	2	was	be	AUX
cet-14807	7	3	used	use	VERB
cet-14807	7	4	as	as	ADP
cet-14807	7	5	a	a	DET
cet-14807	7	6	control	control	NOUN
cet-14807	7	7	drug	drug	NOUN
cet-14807	7	8	.	.	PUNCT
cet-14807	8	1	out	out	ADP
cet-14807	8	2	of	of	ADP
cet-14807	8	3	over	over	ADP
cet-14807	8	4	200	200	NUM
cet-14807	8	5	phytochemicals	phytochemical	NOUN
cet-14807	8	6	present	present	ADJ
cet-14807	8	7	in	in	ADP
cet-14807	8	8	tawa	tawa	NOUN
cet-14807	8	9	-	-	PUNCT
cet-14807	8	10	tawa	tawa	PROPN
cet-14807	8	11	,	,	PUNCT
cet-14807	8	12	18	18	NUM
cet-14807	8	13	were	be	AUX
cet-14807	8	14	identified	identify	VERB
cet-14807	8	15	with	with	ADP
cet-14807	8	16	binding	bind	VERB
cet-14807	8	17	affinities	affinity	NOUN
cet-14807	8	18	ranging	range	VERB
cet-14807	8	19	from	from	ADP
cet-14807	8	20	-10.50	-10.50	PROPN
cet-14807	8	21	to	to	ADP
cet-14807	8	22	-5.76	-5.76	ADJ
cet-14807	8	23	kcal	kcal	PROPN
cet-14807	8	24	/	/	SYM
cet-14807	8	25	mol	mol	PROPN
cet-14807	8	26	,	,	PUNCT
cet-14807	8	27	all	all	PRON
cet-14807	8	28	surpassing	surpass	VERB
cet-14807	8	29	the	the	DET
cet-14807	8	30	control	control	NOUN
cet-14807	8	31	drug	drug	NOUN
cet-14807	8	32	ribavirin	ribavirin	NOUN
cet-14807	8	33	's	's	PART
cet-14807	8	34	affinity	affinity	NOUN
cet-14807	8	35	of	of	ADP
cet-14807	8	36	-5.41	-5.41	X
cet-14807	8	37	kcal	kcal	PROPN
cet-14807	8	38	/	/	SYM
cet-14807	8	39	mol	mol	PROPN
cet-14807	8	40	.	.	PUNCT
cet-14807	9	1	further	further	ADJ
cet-14807	9	2	analysis	analysis	NOUN
cet-14807	9	3	using	use	VERB
cet-14807	9	4	lipinski	lipinski	PROPN
cet-14807	9	5	's	's	PART
cet-14807	9	6	rule	rule	NOUN
cet-14807	9	7	and	and	CCONJ
cet-14807	9	8	admet	admet	PROPN
cet-14807	9	9	tests	test	NOUN
cet-14807	9	10	narrowed	narrow	VERB
cet-14807	9	11	these	these	DET
cet-14807	9	12	18	18	NUM
cet-14807	9	13	candidates	candidate	NOUN
cet-14807	9	14	down	down	ADV
cet-14807	9	15	to	to	ADP
cet-14807	9	16	three	three	NUM
cet-14807	9	17	potential	potential	ADJ
cet-14807	9	18	drug	drug	NOUN
cet-14807	9	19	candidates	candidate	NOUN
cet-14807	9	20	.	.	PUNCT
cet-14807	10	1	three	three	NUM
cet-14807	10	2	compounds	compound	NOUN
cet-14807	10	3	—	—	PUNCT
cet-14807	10	4	corchoionoside	corchoionoside	NOUN
cet-14807	10	5	c	c	NOUN
cet-14807	10	6	,	,	PUNCT
cet-14807	10	7	luteolin-7	luteolin-7	NOUN
cet-14807	10	8	-	-	PUNCT
cet-14807	10	9	o	o	NOUN
cet-14807	10	10	-	-	ADJ
cet-14807	10	11	beta	beta	NOUN
cet-14807	10	12	-	-	PUNCT
cet-14807	10	13	d	d	NOUN
cet-14807	10	14	-	-	PUNCT
cet-14807	10	15	glucopyranoside	glucopyranoside	NOUN
cet-14807	10	16	,	,	PUNCT
cet-14807	10	17	and	and	CCONJ
cet-14807	10	18	corilagin	corilagin	NOUN
cet-14807	10	19	—	—	PUNCT
cet-14807	10	20	exhibit	exhibit	VERB
cet-14807	10	21	promising	promise	VERB
cet-14807	10	22	binding	bind	VERB
cet-14807	10	23	affinities	affinity	NOUN
cet-14807	10	24	and	and	CCONJ
cet-14807	10	25	hydrogen	hydrogen	NOUN
cet-14807	10	26	bond	bond	NOUN
cet-14807	10	27	interactions	interaction	NOUN
cet-14807	10	28	with	with	ADP
cet-14807	10	29	the	the	DET
cet-14807	10	30	protease	protease	NOUN
cet-14807	10	31	this	this	DET
cet-14807	10	32	study	study	NOUN
cet-14807	10	33	provides	provide	VERB
cet-14807	10	34	a	a	DET
cet-14807	10	35	deep	deep	ADJ
cet-14807	10	36	understanding	understanding	NOUN
cet-14807	10	37	of	of	ADP
cet-14807	10	38	tawa	tawa	PROPN
cet-14807	10	39	-	-	PUNCT
cet-14807	10	40	tawa	tawa	PROPN
cet-14807	10	41	’s	’s	PART
cet-14807	10	42	bioactive	bioactive	PROPN
cet-14807	10	43	components	component	NOUN
cet-14807	10	44	interacting	interact	VERB
cet-14807	10	45	with	with	ADP
cet-14807	10	46	the	the	DET
cet-14807	10	47	catalytic	catalytic	ADJ
cet-14807	10	48	triad	triad	NUM
cet-14807	10	49	of	of	ADP
cet-14807	10	50	the	the	DET
cet-14807	10	51	ns2b	ns2b	NOUN
cet-14807	10	52	-	-	PUNCT
cet-14807	10	53	ns3	ns3	NOUN
cet-14807	10	54	protease	protease	NOUN
cet-14807	10	55	of	of	ADP
cet-14807	10	56	denv-2	denv-2	PROPN
cet-14807	10	57	and	and	CCONJ
cet-14807	10	58	predicts	predict	VERB
cet-14807	10	59	the	the	DET
cet-14807	10	60	admet	admet	PROPN
cet-14807	10	61	profiles	profile	NOUN
cet-14807	10	62	to	to	PART
cet-14807	10	63	assess	assess	VERB
cet-14807	10	64	potential	potential	ADJ
cet-14807	10	65	toxicity	toxicity	NOUN
cet-14807	10	66	.	.	PUNCT
cet-14807	11	1	1	1	X
cet-14807	11	2	.	.	X
cet-14807	11	3	introduction	introduction	NOUN
cet-14807	11	4	the	the	DET
cet-14807	11	5	primary	primary	ADJ
cet-14807	11	6	transmission	transmission	NOUN
cet-14807	11	7	of	of	ADP
cet-14807	11	8	dengue	dengue	NOUN
cet-14807	11	9	,	,	PUNCT
cet-14807	11	10	which	which	PRON
cet-14807	11	11	is	be	AUX
cet-14807	11	12	the	the	DET
cet-14807	11	13	dengue	dengue	NOUN
cet-14807	11	14	fever	fever	NOUN
cet-14807	11	15	virus	virus	NOUN
cet-14807	11	16	(	(	PUNCT
cet-14807	11	17	denv	denv	NOUN
cet-14807	11	18	)	)	PUNCT
cet-14807	11	19	,	,	PUNCT
cet-14807	11	20	is	be	AUX
cet-14807	11	21	the	the	DET
cet-14807	11	22	aedes	aedes	PROPN
cet-14807	11	23	aegypti	aegypti	VERB
cet-14807	11	24	mosquito	mosquito	NOUN
cet-14807	11	25	.	.	PUNCT
cet-14807	12	1	it	it	PRON
cet-14807	12	2	may	may	AUX
cet-14807	12	3	result	result	VERB
cet-14807	12	4	in	in	ADP
cet-14807	12	5	minor	minor	ADJ
cet-14807	12	6	symptoms	symptom	NOUN
cet-14807	12	7	or	or	CCONJ
cet-14807	12	8	serious	serious	ADJ
cet-14807	12	9	illnesses	illness	NOUN
cet-14807	12	10	like	like	ADP
cet-14807	12	11	dengue	dengue	NOUN
cet-14807	12	12	shock	shock	NOUN
cet-14807	12	13	syndrome	syndrome	PROPN
cet-14807	12	14	(	(	PUNCT
cet-14807	12	15	dss	dss	NOUN
cet-14807	12	16	)	)	PUNCT
cet-14807	12	17	and	and	CCONJ
cet-14807	12	18	dengue	dengue	NOUN
cet-14807	12	19	hemorrhagic	hemorrhagic	NOUN
cet-14807	12	20	fever	fever	NOUN
cet-14807	12	21	(	(	PUNCT
cet-14807	12	22	dhf	dhf	NOUN
cet-14807	12	23	)	)	PUNCT
cet-14807	12	24	(	(	PUNCT
cet-14807	12	25	nanaware	nanaware	NOUN
cet-14807	12	26	et	et	PROPN
cet-14807	12	27	al	al	PROPN
cet-14807	12	28	.	.	PROPN
cet-14807	12	29	,	,	PUNCT
cet-14807	12	30	2021	2021	NUM
cet-14807	12	31	)	)	PUNCT
cet-14807	12	32	.	.	PUNCT
cet-14807	13	1	even	even	ADV
cet-14807	13	2	though	though	SCONJ
cet-14807	13	3	dengue	dengue	NOUN
cet-14807	13	4	has	have	AUX
cet-14807	13	5	spread	spread	VERB
cet-14807	13	6	widely	widely	ADV
cet-14807	13	7	throughout	throughout	ADP
cet-14807	13	8	the	the	DET
cet-14807	13	9	philippines	philippine	NOUN
cet-14807	13	10	since	since	SCONJ
cet-14807	13	11	1958	1958	NUM
cet-14807	13	12	,	,	PUNCT
cet-14807	13	13	there	there	PRON
cet-14807	13	14	is	be	VERB
cet-14807	13	15	n't	not	PART
cet-14807	13	16	a	a	DET
cet-14807	13	17	vaccination	vaccination	NOUN
cet-14807	13	18	that	that	PRON
cet-14807	13	19	fights	fight	VERB
cet-14807	13	20	against	against	ADP
cet-14807	13	21	all	all	DET
cet-14807	13	22	four	four	NUM
cet-14807	13	23	denv	denv	NOUN
cet-14807	13	24	serotypes	serotype	NOUN
cet-14807	13	25	(	(	PUNCT
cet-14807	13	26	undurraga	undurraga	NOUN
cet-14807	13	27	et	et	PROPN
cet-14807	13	28	al	al	PROPN
cet-14807	13	29	.	.	PROPN
cet-14807	13	30	,	,	PUNCT
cet-14807	13	31	2017	2017	NUM
cet-14807	13	32	)	)	PUNCT
cet-14807	13	33	.	.	PUNCT
cet-14807	14	1	as	as	ADP
cet-14807	14	2	of	of	ADP
cet-14807	14	3	september	september	PROPN
cet-14807	14	4	2022	2022	NUM
cet-14807	14	5	,	,	PUNCT
cet-14807	14	6	the	the	PRON
cet-14807	14	7	who	who	PRON
cet-14807	14	8	reported	report	VERB
cet-14807	14	9	128,346	128,346	NUM
cet-14807	14	10	cases	case	NOUN
cet-14807	14	11	from	from	ADP
cet-14807	14	12	january	january	PROPN
cet-14807	14	13	1	1	NUM
cet-14807	14	14	to	to	ADP
cet-14807	14	15	august	august	PROPN
cet-14807	14	16	20	20	NUM
cet-14807	14	17	,	,	PUNCT
cet-14807	14	18	a	a	DET
cet-14807	14	19	152	152	NUM
cet-14807	14	20	%	%	NOUN
cet-14807	14	21	increase	increase	NOUN
cet-14807	14	22	from	from	ADP
cet-14807	14	23	2021	2021	NUM
cet-14807	14	24	(	(	PUNCT
cet-14807	14	25	world	world	NOUN
cet-14807	14	26	health	health	NOUN
cet-14807	14	27	organization	organization	NOUN
cet-14807	14	28	,	,	PUNCT
cet-14807	14	29	2022	2022	NUM
cet-14807	14	30	)	)	PUNCT
cet-14807	14	31	.	.	PUNCT
cet-14807	15	1	plants	plant	NOUN
cet-14807	15	2	have	have	VERB
cet-14807	15	3	several	several	ADJ
cet-14807	15	4	phytochemicals	phytochemical	NOUN
cet-14807	15	5	that	that	PRON
cet-14807	15	6	could	could	AUX
cet-14807	15	7	inhibit	inhibit	VERB
cet-14807	15	8	the	the	DET
cet-14807	15	9	dengue	dengue	NOUN
cet-14807	15	10	virus	virus	NOUN
cet-14807	15	11	thus	thus	ADV
cet-14807	15	12	extraction	extraction	NOUN
cet-14807	15	13	of	of	ADP
cet-14807	15	14	phytochemicals	phytochemical	NOUN
cet-14807	15	15	is	be	AUX
cet-14807	15	16	optimized	optimize	VERB
cet-14807	15	17	using	use	VERB
cet-14807	15	18	several	several	ADJ
cet-14807	15	19	methods	method	NOUN
cet-14807	15	20	(	(	PUNCT
cet-14807	15	21	laina	laina	PROPN
cet-14807	15	22	et	et	PROPN
cet-14807	15	23	al	al	PROPN
cet-14807	15	24	.	.	PROPN
cet-14807	15	25	,	,	PUNCT
cet-14807	15	26	2021	2021	NUM
cet-14807	15	27	)	)	PUNCT
cet-14807	15	28	.	.	PUNCT
cet-14807	16	1	the	the	DET
cet-14807	16	2	pharmacological	pharmacological	ADJ
cet-14807	16	3	properties	property	NOUN
cet-14807	16	4	of	of	ADP
cet-14807	16	5	tawa	tawa	PROPN
cet-14807	16	6	-	-	PUNCT
cet-14807	16	7	tawa	tawa	PROPN
cet-14807	16	8	(	(	PUNCT
cet-14807	16	9	euphorbia	euphorbia	PROPN
cet-14807	16	10	hirta	hirta	PROPN
cet-14807	16	11	l.	l.	PROPN
cet-14807	16	12	)	)	PUNCT
cet-14807	16	13	include	include	VERB
cet-14807	16	14	antibacterial	antibacterial	ADJ
cet-14807	16	15	,	,	PUNCT
cet-14807	16	16	antimalarial	antimalarial	NOUN
cet-14807	16	17	,	,	PUNCT
cet-14807	16	18	and	and	CCONJ
cet-14807	16	19	antiinflammatory	antiinflammatory	NOUN
cet-14807	16	20	properties	property	NOUN
cet-14807	16	21	(	(	PUNCT
cet-14807	16	22	kumar	kumar	PROPN
cet-14807	16	23	et	et	PROPN
cet-14807	16	24	al	al	PROPN
cet-14807	16	25	.	.	PROPN
cet-14807	16	26	,	,	PUNCT
cet-14807	16	27	2010	2010	NUM
cet-14807	16	28	)	)	PUNCT
cet-14807	16	29	.	.	PUNCT
cet-14807	17	1	according	accord	VERB
cet-14807	17	2	to	to	ADP
cet-14807	17	3	recent	recent	ADJ
cet-14807	17	4	research	research	NOUN
cet-14807	17	5	,	,	PUNCT
cet-14807	17	6	it	it	PRON
cet-14807	17	7	might	might	AUX
cet-14807	17	8	suppress	suppress	VERB
cet-14807	17	9	viruses	virus	NOUN
cet-14807	17	10	including	include	VERB
cet-14807	17	11	malaria	malaria	NOUN
cet-14807	17	12	(	(	PUNCT
cet-14807	17	13	shah	shah	PROPN
cet-14807	17	14	et	et	PROPN
cet-14807	17	15	al	al	PROPN
cet-14807	17	16	.	.	PROPN
cet-14807	17	17	,	,	PUNCT
cet-14807	17	18	2019	2019	NUM
cet-14807	17	19	)	)	PUNCT
cet-14807	17	20	and	and	CCONJ
cet-14807	17	21	sars	sars	PROPN
cet-14807	17	22	-	-	PUNCT
cet-14807	17	23	cov-2(cayona	cov-2(cayona	PROPN
cet-14807	17	24	and	and	CCONJ
cet-14807	17	25	creencia	creencia	NOUN
cet-14807	17	26	,	,	PUNCT
cet-14807	17	27	2022	2022	NUM
cet-14807	17	28	)	)	PUNCT
cet-14807	17	29	.	.	PUNCT
cet-14807	18	1	there	there	PRON
cet-14807	18	2	are	be	VERB
cet-14807	18	3	298	298	NUM
cet-14807	18	4	identified	identify	VERB
cet-14807	18	5	phytochemicals	phytochemical	NOUN
cet-14807	18	6	present	present	ADJ
cet-14807	18	7	in	in	ADP
cet-14807	18	8	euphorbia	euphorbia	ADJ
cet-14807	18	9	hirta	hirta	PROPN
cet-14807	18	10	l.	l.	PROPN
cet-14807	18	11	(	(	PUNCT
cet-14807	18	12	cayona	cayona	NOUN
cet-14807	18	13	and	and	CCONJ
cet-14807	18	14	creencia	creencia	NOUN
cet-14807	18	15	,	,	PUNCT
cet-14807	18	16	2022	2022	NUM
cet-14807	18	17	)	)	PUNCT
cet-14807	18	18	.	.	PUNCT
cet-14807	19	1	the	the	DET
cet-14807	19	2	efficacy	efficacy	NOUN
cet-14807	19	3	of	of	ADP
cet-14807	19	4	these	these	DET
cet-14807	19	5	phytochemicals	phytochemical	NOUN
cet-14807	19	6	against	against	ADP
cet-14807	19	7	the	the	DET
cet-14807	19	8	dengue	dengue	NOUN
cet-14807	19	9	virus	virus	NOUN
cet-14807	19	10	has	have	AUX
cet-14807	19	11	not	not	PART
cet-14807	19	12	yet	yet	ADV
cet-14807	19	13	been	be	AUX
cet-14807	19	14	studied	study	VERB
cet-14807	19	15	.	.	PUNCT
cet-14807	20	1	current	current	ADJ
cet-14807	20	2	research	research	NOUN
cet-14807	20	3	lacks	lack	VERB
cet-14807	20	4	the	the	DET
cet-14807	20	5	identification	identification	NOUN
cet-14807	20	6	of	of	ADP
cet-14807	20	7	tawa	tawa	PROPN
cet-14807	20	8	-	-	PUNCT
cet-14807	20	9	tawa	tawa	PROPN
cet-14807	20	10	bioactive	bioactive	ADJ
cet-14807	20	11	compounds	compound	NOUN
cet-14807	20	12	that	that	PRON
cet-14807	20	13	may	may	AUX
cet-14807	20	14	inhibit	inhibit	VERB
cet-14807	20	15	denv	denv	NOUN
cet-14807	20	16	replication	replication	NOUN
cet-14807	20	17	.	.	PUNCT
cet-14807	21	1	this	this	DET
cet-14807	21	2	study	study	NOUN
cet-14807	21	3	aims	aim	VERB
cet-14807	21	4	to	to	PART
cet-14807	21	5	fill	fill	VERB
cet-14807	21	6	this	this	DET
cet-14807	21	7	gap	gap	NOUN
cet-14807	21	8	by	by	ADP
cet-14807	21	9	utilizing	utilize	VERB
cet-14807	21	10	bioactive	bioactive	ADJ
cet-14807	21	11	compounds	compound	NOUN
cet-14807	21	12	from	from	ADP
cet-14807	21	13	tawa	tawa	NOUN
cet-14807	21	14	-	-	PUNCT
cet-14807	21	15	tawa	tawa	PROPN
cet-14807	21	16	to	to	PART
cet-14807	21	17	mimic	mimic	VERB
cet-14807	21	18	the	the	DET
cet-14807	21	19	inhibition	inhibition	NOUN
cet-14807	21	20	of	of	ADP
cet-14807	21	21	the	the	DET
cet-14807	21	22	ns2b	ns2b	NOUN
cet-14807	21	23	-	-	PUNCT
cet-14807	21	24	ns3	ns3	NOUN
cet-14807	21	25	protease	protease	NOUN
cet-14807	21	26	of	of	ADP
cet-14807	21	27	denv-2	denv-2	PROPN
cet-14807	21	28	.	.	PUNCT
cet-14807	22	1	the	the	DET
cet-14807	22	2	approach	approach	NOUN
cet-14807	22	3	employs	employ	VERB
cet-14807	22	4	autodock	autodock	PROPN
cet-14807	22	5	vina	vina	NOUN
cet-14807	22	6	for	for	ADP
cet-14807	22	7	ligand	ligand	NOUN
cet-14807	22	8	interaction	interaction	NOUN
cet-14807	22	9	analysis	analysis	NOUN
cet-14807	22	10	,	,	PUNCT
cet-14807	22	11	virtual	virtual	ADJ
cet-14807	22	12	screening	screening	NOUN
cet-14807	22	13	,	,	PUNCT
cet-14807	22	14	and	and	CCONJ
cet-14807	22	15	molecular	molecular	ADJ
cet-14807	22	16	docking	docking	NOUN
cet-14807	22	17	.	.	PUNCT
cet-14807	23	1	autodock	autodock	PROPN
cet-14807	23	2	vina	vina	PROPN
cet-14807	23	3	is	be	AUX
cet-14807	23	4	widely	widely	ADV
cet-14807	23	5	recognized	recognize	VERB
cet-14807	23	6	as	as	ADP
cet-14807	23	7	a	a	DET
cet-14807	23	8	standard	standard	ADJ
cet-14807	23	9	tool	tool	NOUN
cet-14807	23	10	for	for	ADP
cet-14807	23	11	drug	drug	NOUN
cet-14807	23	12	screening	screening	NOUN
cet-14807	23	13	due	due	ADP
cet-14807	23	14	to	to	ADP
cet-14807	23	15	its	its	PRON
cet-14807	23	16	efficiency	efficiency	NOUN
cet-14807	23	17	and	and	CCONJ
cet-14807	23	18	accuracy	accuracy	NOUN
cet-14807	23	19	in	in	ADP
cet-14807	23	20	molecular	molecular	ADJ
cet-14807	23	21	docking	docking	NOUN
cet-14807	23	22	(	(	PUNCT
cet-14807	23	23	gaillard	gaillard	PROPN
cet-14807	23	24	,	,	PUNCT
cet-14807	23	25	2018	2018	NUM
cet-14807	23	26	)	)	PUNCT
cet-14807	23	27	.	.	PUNCT
cet-14807	24	1	it	it	PRON
cet-14807	24	2	is	be	AUX
cet-14807	24	3	frequently	frequently	ADV
cet-14807	24	4	used	use	VERB
cet-14807	24	5	in	in	ADP
cet-14807	24	6	modern	modern	ADJ
cet-14807	24	7	drug	drug	NOUN
cet-14807	24	8	discovery	discovery	NOUN
cet-14807	24	9	for	for	ADP
cet-14807	24	10	predicting	predict	VERB
cet-14807	24	11	the	the	DET
cet-14807	24	12	binding	binding	NOUN
cet-14807	24	13	of	of	ADP
cet-14807	24	14	small	small	ADJ
cet-14807	24	15	molecules	molecule	NOUN
cet-14807	24	16	to	to	ADP
cet-14807	24	17	protein	protein	NOUN
cet-14807	24	18	targets	target	NOUN
cet-14807	24	19	.	.	PUNCT
cet-14807	25	1	biovia	biovia	PROPN
cet-14807	25	2	will	will	AUX
cet-14807	25	3	also	also	ADV
cet-14807	25	4	be	be	AUX
cet-14807	25	5	used	use	VERB
cet-14807	25	6	to	to	PART
cet-14807	25	7	visualize	visualize	VERB
cet-14807	25	8	the	the	DET
cet-14807	25	9	intermolecular	intermolecular	ADJ
cet-14807	25	10	forces	force	NOUN
cet-14807	25	11	of	of	ADP
cet-14807	25	12	attraction	attraction	NOUN
cet-14807	25	13	between	between	ADP
cet-14807	25	14	the	the	DET
cet-14807	25	15	ligand	ligand	NOUN
cet-14807	25	16	and	and	CCONJ
cet-14807	25	17	the	the	DET
cet-14807	25	18	dengue	dengue	NOUN
cet-14807	25	19	virus.the	virus.the	DET
cet-14807	25	20	study	study	NOUN
cet-14807	25	21	will	will	AUX
cet-14807	25	22	also	also	ADV
cet-14807	25	23	utilize	utilize	VERB
cet-14807	25	24	admetox	admetox	NOUN
cet-14807	25	25	to	to	PART
cet-14807	25	26	screen	screen	VERB
cet-14807	25	27	potential	potential	ADJ
cet-14807	25	28	drugs	drug	NOUN
cet-14807	25	29	for	for	ADP
cet-14807	25	30	oral	oral	ADJ
cet-14807	25	31	viability	viability	NOUN
cet-14807	25	32	,	,	PUNCT
cet-14807	25	33	carcinogenicity	carcinogenicity	NOUN
cet-14807	25	34	,	,	PUNCT
cet-14807	25	35	hepatotoxicity	hepatotoxicity	NOUN
cet-14807	25	36	,	,	PUNCT
cet-14807	25	37	blood	blood	NOUN
cet-14807	25	38	-	-	PUNCT
cet-14807	25	39	brain	brain	NOUN
cet-14807	25	40	barrier	barrier	NOUN
cet-14807	25	41	(	(	PUNCT
cet-14807	25	42	bbb	bbb	NOUN
cet-14807	25	43	)	)	PUNCT
cet-14807	25	44	penetration	penetration	NOUN
cet-14807	25	45	,	,	PUNCT
cet-14807	25	46	and	and	CCONJ
cet-14807	25	47	ld50	ld50	PROPN
cet-14807	25	48	category	category	NOUN
cet-14807	25	49	.	.	PUNCT
cet-14807	26	1	in	in	ADP
cet-14807	26	2	silico	silico	NOUN
cet-14807	26	3	67	67	NUM
cet-14807	26	4	adme	adme	NOUN
cet-14807	26	5	-	-	PUNCT
cet-14807	26	6	tox	tox	NOUN
cet-14807	26	7	prediction	prediction	NOUN
cet-14807	26	8	remains	remain	VERB
cet-14807	26	9	crucial	crucial	ADJ
cet-14807	26	10	in	in	ADP
cet-14807	26	11	aiding	aid	VERB
cet-14807	26	12	pharmaceutical	pharmaceutical	ADJ
cet-14807	26	13	companies	company	NOUN
cet-14807	26	14	to	to	PART
cet-14807	26	15	select	select	VERB
cet-14807	26	16	suitable	suitable	ADJ
cet-14807	26	17	candidate	candidate	NOUN
cet-14807	26	18	drugs	drug	NOUN
cet-14807	26	19	before	before	ADP
cet-14807	26	20	investing	invest	VERB
cet-14807	26	21	in	in	ADP
cet-14807	26	22	costly	costly	ADJ
cet-14807	26	23	clinical	clinical	ADJ
cet-14807	26	24	trials	trial	NOUN
cet-14807	26	25	(	(	PUNCT
cet-14807	26	26	alqahtani	alqahtani	ADJ
cet-14807	26	27	,	,	PUNCT
cet-14807	26	28	2017	2017	NUM
cet-14807	26	29	)	)	PUNCT
cet-14807	26	30	2	2	NUM
cet-14807	26	31	.	.	X
cet-14807	26	32	methodology	methodology	NOUN
cet-14807	26	33	2.1	2.1	NUM
cet-14807	26	34	ligand	ligand	NOUN
cet-14807	26	35	preparation	preparation	NOUN
cet-14807	26	36	eighteen	eighteen	NUM
cet-14807	26	37	high	high	ADJ
cet-14807	26	38	scoring	scoring	NOUN
cet-14807	26	39	(	(	PUNCT
cet-14807	26	40	based	base	VERB
cet-14807	26	41	on	on	ADP
cet-14807	26	42	docking	dock	VERB
cet-14807	26	43	score	score	NOUN
cet-14807	26	44	)	)	PUNCT
cet-14807	26	45	bioactive	bioactive	ADJ
cet-14807	26	46	components	component	NOUN
cet-14807	26	47	of	of	ADP
cet-14807	26	48	tawa	tawa	PROPN
cet-14807	26	49	-	-	PUNCT
cet-14807	26	50	tawa	tawa	PROPN
cet-14807	26	51	(	(	PUNCT
cet-14807	26	52	euphorbia	euphorbia	PROPN
cet-14807	26	53	hirta	hirta	PROPN
cet-14807	26	54	l.	l.	PROPN
cet-14807	26	55	)	)	PUNCT
cet-14807	26	56	leaves	leave	NOUN
cet-14807	26	57	and	and	CCONJ
cet-14807	26	58	the	the	DET
cet-14807	26	59	control	control	NOUN
cet-14807	26	60	drug	drug	PROPN
cet-14807	26	61	ribavirin	ribavirin	NOUN
cet-14807	26	62	were	be	AUX
cet-14807	26	63	identified	identify	VERB
cet-14807	26	64	.	.	PUNCT
cet-14807	27	1	these	these	DET
cet-14807	27	2	compounds	compound	NOUN
cet-14807	27	3	were	be	AUX
cet-14807	27	4	downloaded	download	VERB
cet-14807	27	5	in	in	ADP
cet-14807	27	6	3d	3d	PROPN
cet-14807	27	7	conformer	conformer	PROPN
cet-14807	27	8	sdf	sdf	PROPN
cet-14807	27	9	file	file	NOUN
cet-14807	27	10	format	format	NOUN
cet-14807	27	11	from	from	ADP
cet-14807	27	12	pubchem	pubchem	NOUN
cet-14807	27	13	,	,	PUNCT
cet-14807	27	14	converted	convert	VERB
cet-14807	27	15	to	to	ADP
cet-14807	27	16	pdb	pdb	PROPN
cet-14807	27	17	files	file	NOUN
cet-14807	27	18	using	use	VERB
cet-14807	27	19	cygwin	cygwin	PROPN
cet-14807	27	20	and	and	CCONJ
cet-14807	27	21	open	open	ADJ
cet-14807	27	22	babel	babel	NOUN
cet-14807	27	23	,	,	PUNCT
cet-14807	27	24	and	and	CCONJ
cet-14807	27	25	prepared	prepare	VERB
cet-14807	27	26	for	for	ADP
cet-14807	27	27	molecular	molecular	ADJ
cet-14807	27	28	docking	docking	NOUN
cet-14807	27	29	using	use	VERB
cet-14807	27	30	autodocktools	autodocktool	NOUN
cet-14807	27	31	by	by	ADP
cet-14807	27	32	adding	add	VERB
cet-14807	27	33	gasteiger	gasteiger	NOUN
cet-14807	27	34	charges	charge	NOUN
cet-14807	27	35	and	and	CCONJ
cet-14807	27	36	saving	save	VERB
cet-14807	27	37	them	they	PRON
cet-14807	27	38	as	as	ADP
cet-14807	27	39	pdbqt	pdbqt	NOUN
cet-14807	27	40	files	file	NOUN
cet-14807	27	41	.	.	PUNCT
cet-14807	28	1	the	the	DET
cet-14807	28	2	retrieved	retrieve	VERB
cet-14807	28	3	eighteen	eighteen	NUM
cet-14807	28	4	bioactive	bioactive	ADJ
cet-14807	28	5	components	component	NOUN
cet-14807	28	6	cid	cid	NOUN
cet-14807	28	7	and	and	CCONJ
cet-14807	28	8	2d	2d	NUM
cet-14807	28	9	structure	structure	NOUN
cet-14807	28	10	were	be	AUX
cet-14807	28	11	presented	present	VERB
cet-14807	28	12	in	in	ADP
cet-14807	28	13	table	table	NOUN
cet-14807	28	14	1	1	NUM
cet-14807	28	15	.	.	PUNCT
cet-14807	28	16	table	table	NOUN
cet-14807	28	17	1	1	NUM
cet-14807	28	18	:	:	PUNCT
cet-14807	28	19	the	the	DET
cet-14807	28	20	18	18	NUM
cet-14807	28	21	bioactive	bioactive	ADJ
cet-14807	28	22	components	component	NOUN
cet-14807	28	23	of	of	ADP
cet-14807	28	24	euphorbia	euphorbia	ADJ
cet-14807	28	25	hirta	hirta	PROPN
cet-14807	28	26	l.	l.	PROPN
cet-14807	28	27	with	with	ADP
cet-14807	28	28	pubchem	pubchem	NOUN
cet-14807	28	29	cid	cid	NOUN
cet-14807	28	30	and	and	CCONJ
cet-14807	28	31	2d	2d	NUM
cet-14807	28	32	chemical	chemical	NOUN
cet-14807	28	33	structure	structure	NOUN
cet-14807	28	34	.	.	PUNCT
cet-14807	29	1	compounds	compound	NOUN
cet-14807	29	2	(	(	PUNCT
cet-14807	29	3	cid	cid	NOUN
cet-14807	29	4	)	)	PUNCT
cet-14807	29	5	2d	2d	NUM
cet-14807	29	6	structure	structure	NOUN
cet-14807	29	7	compound	compound	NOUN
cet-14807	29	8	(	(	PUNCT
cet-14807	29	9	cid	cid	NOUN
cet-14807	29	10	)	)	PUNCT
cet-14807	29	11	2d	2d	NOUN
cet-14807	29	12	structure	structure	NOUN
cet-14807	29	13	compounds	compound	NOUN
cet-14807	29	14	(	(	PUNCT
cet-14807	29	15	cid	cid	NOUN
cet-14807	29	16	)	)	PUNCT
cet-14807	29	17	2d	2d	NOUN
cet-14807	29	18	structure	structure	NOUN
cet-14807	29	19	24	24	NUM
cet-14807	29	20	-	-	PUNCT
cet-14807	29	21	hydroperoxycycloart25	hydroperoxycycloart25	NOUN
cet-14807	29	22	-	-	PUNCT
cet-14807	29	23	en-3beta	en-3beta	PROPN
cet-14807	29	24	-	-	PUNCT
cet-14807	29	25	ol	ol	PROPN
cet-14807	29	26	(	(	PUNCT
cet-14807	29	27	15293070	15293070	NUM
cet-14807	29	28	)	)	PUNCT
cet-14807	29	29	cycloart-23	cycloart-23	NOUN
cet-14807	29	30	-	-	PUNCT
cet-14807	29	31	ene3beta,25	ene3beta,25	NOUN
cet-14807	29	32	-	-	PUNCT
cet-14807	29	33	diol	diol	NOUN
cet-14807	29	34	(	(	PUNCT
cet-14807	29	35	5470009	5470009	NUM
cet-14807	29	36	)	)	PUNCT
cet-14807	29	37	kaempferol-3	kaempferol-3	NOUN
cet-14807	29	38	-	-	PUNCT
cet-14807	29	39	oglucuronide	oglucuronide	NOUN
cet-14807	29	40	(	(	PUNCT
cet-14807	29	41	74315888	74315888	NUM
cet-14807	29	42	)	)	PUNCT
cet-14807	29	43	2	2	NUM
cet-14807	29	44	-	-	PUNCT
cet-14807	29	45	coumaroylquinic	coumaroylquinic	ADJ
cet-14807	29	46	acid	acid	NOUN
cet-14807	29	47	(	(	PUNCT
cet-14807	29	48	6441280	6441280	NUM
cet-14807	29	49	)	)	PUNCT
cet-14807	29	50	ellagic	ellagic	ADJ
cet-14807	29	51	acid	acid	NOUN
cet-14807	29	52	(	(	PUNCT
cet-14807	29	53	5281855	5281855	NUM
cet-14807	29	54	)	)	PUNCT
cet-14807	29	55	luteolin-7	luteolin-7	PROPN
cet-14807	29	56	-	-	PUNCT
cet-14807	29	57	o	o	NOUN
cet-14807	29	58	-	-	ADJ
cet-14807	29	59	beta	beta	NOUN
cet-14807	29	60	-	-	PUNCT
cet-14807	29	61	dglucopyranoside	dglucopyranoside	NOUN
cet-14807	29	62	(	(	PUNCT
cet-14807	29	63	14032967	14032967	NUM
cet-14807	29	64	)	)	PUNCT
cet-14807	29	65	brevifolin	brevifolin	NOUN
cet-14807	29	66	carboxylic	carboxylic	ADJ
cet-14807	29	67	acid	acid	NOUN
cet-14807	29	68	(	(	PUNCT
cet-14807	29	69	9838995	9838995	NUM
cet-14807	29	70	)	)	PUNCT
cet-14807	29	71	epicatechin	epicatechin	NOUN
cet-14807	29	72	(	(	PUNCT
cet-14807	29	73	72276	72276	NUM
cet-14807	29	74	)	)	PUNCT
cet-14807	29	75	syringin	syringin	NOUN
cet-14807	29	76	(	(	PUNCT
cet-14807	29	77	5316860	5316860	NUM
cet-14807	29	78	)	)	PUNCT
cet-14807	29	79	chelidonic	chelidonic	ADJ
cet-14807	29	80	acid	acid	NOUN
cet-14807	29	81	(	(	PUNCT
cet-14807	29	82	7431	7431	NUM
cet-14807	29	83	)	)	PUNCT
cet-14807	29	84	feruloyl	feruloyl	ADJ
cet-14807	29	85	malate	malate	NOUN
cet-14807	29	86	(	(	PUNCT
cet-14807	29	87	71694479	71694479	NUM
cet-14807	29	88	)	)	PUNCT
cet-14807	29	89	trigallic	trigallic	ADJ
cet-14807	29	90	acid	acid	NOUN
cet-14807	29	91	(	(	PUNCT
cet-14807	29	92	90470472	90470472	NUM
cet-14807	29	93	)	)	PUNCT
cet-14807	29	94	corchoionoside	corchoionoside	NOUN
cet-14807	29	95	c	c	PROPN
cet-14807	29	96	(	(	PUNCT
cet-14807	29	97	10317980	10317980	NUM
cet-14807	29	98	)	)	PUNCT
cet-14807	29	99	hyperoside	hyperoside	NOUN
cet-14807	29	100	(	(	PUNCT
cet-14807	29	101	5281643	5281643	NUM
cet-14807	29	102	)	)	PUNCT
cet-14807	29	103	tryptophan	tryptophan	NOUN
cet-14807	29	104	(	(	PUNCT
cet-14807	29	105	6305	6305	NUM
cet-14807	29	106	)	)	PUNCT
cet-14807	29	107	corilagin	corilagin	NOUN
cet-14807	29	108	(	(	PUNCT
cet-14807	29	109	73568	73568	NUM
cet-14807	29	110	)	)	PUNCT
cet-14807	29	111	isojaponin	isojaponin	NOUN
cet-14807	29	112	a	a	DET
cet-14807	29	113	(	(	PUNCT
cet-14807	29	114	101836940	101836940	NUM
cet-14807	29	115	)	)	PUNCT
cet-14807	29	116	tyrosylglutamate	tyrosylglutamate	NOUN
cet-14807	29	117	(	(	PUNCT
cet-14807	29	118	19816750	19816750	NUM
cet-14807	29	119	)	)	PUNCT
cet-14807	29	120	2.2	2.2	NUM
cet-14807	29	121	protease	protease	NOUN
cet-14807	29	122	preparation	preparation	NOUN
cet-14807	29	123	the	the	DET
cet-14807	29	124	ns2b	ns2b	NOUN
cet-14807	29	125	-	-	PUNCT
cet-14807	29	126	ns3	ns3	NOUN
cet-14807	29	127	protease	protease	NOUN
cet-14807	29	128	(	(	PUNCT
cet-14807	29	129	pdb	pdb	PROPN
cet-14807	29	130	code	code	PROPN
cet-14807	29	131	:	:	PUNCT
cet-14807	29	132	2fom	2fom	NOUN
cet-14807	29	133	)	)	PUNCT
cet-14807	29	134	was	be	AUX
cet-14807	29	135	prepared	prepare	VERB
cet-14807	29	136	using	use	VERB
cet-14807	29	137	autodocktools	autodocktool	NOUN
cet-14807	29	138	by	by	ADP
cet-14807	29	139	removing	remove	VERB
cet-14807	29	140	water	water	NOUN
cet-14807	29	141	molecules	molecule	NOUN
cet-14807	29	142	and	and	CCONJ
cet-14807	29	143	attached	attach	VERB
cet-14807	29	144	ligands	ligand	NOUN
cet-14807	29	145	and	and	CCONJ
cet-14807	29	146	adding	add	VERB
cet-14807	29	147	polar	polar	ADJ
cet-14807	29	148	hydrogens	hydrogen	NOUN
cet-14807	29	149	and	and	CCONJ
cet-14807	29	150	kollman	kollman	NOUN
cet-14807	29	151	charges	charge	NOUN
cet-14807	29	152	to	to	PART
cet-14807	29	153	improve	improve	VERB
cet-14807	29	154	prediction	prediction	NOUN
cet-14807	29	155	accuracy	accuracy	NOUN
cet-14807	29	156	(	(	PUNCT
cet-14807	29	157	sunani	sunani	PROPN
cet-14807	29	158	et	et	PROPN
cet-14807	29	159	al	al	PROPN
cet-14807	29	160	.	.	PROPN
cet-14807	29	161	,	,	PUNCT
cet-14807	29	162	2022	2022	NUM
cet-14807	29	163	)	)	PUNCT
cet-14807	29	164	.	.	PUNCT
cet-14807	30	1	the	the	DET
cet-14807	30	2	protease	protease	NOUN
cet-14807	30	3	was	be	AUX
cet-14807	30	4	saved	save	VERB
cet-14807	30	5	in	in	ADP
cet-14807	30	6	pdbqt	pdbqt	ADJ
cet-14807	30	7	format	format	NOUN
cet-14807	30	8	.	.	PUNCT
cet-14807	31	1	cavityplus	cavityplus	PROPN
cet-14807	31	2	identified	identify	VERB
cet-14807	31	3	the	the	DET
cet-14807	31	4	best	well	ADV
cet-14807	31	5	binding	bind	VERB
cet-14807	31	6	sites	site	NOUN
cet-14807	31	7	,	,	PUNCT
cet-14807	31	8	with	with	ADP
cet-14807	31	9	grid	grid	NOUN
cet-14807	31	10	box	box	NOUN
cet-14807	31	11	coordinates	coordinate	NOUN
cet-14807	31	12	for	for	ADP
cet-14807	31	13	the	the	DET
cet-14807	31	14	binding	bind	VERB
cet-14807	31	15	site	site	NOUN
cet-14807	31	16	xyz	xyz	PROPN
cet-14807	31	17	coordinates	coordinate	NOUN
cet-14807	31	18	(	(	PUNCT
cet-14807	31	19	96	96	NUM
cet-14807	31	20	,	,	PUNCT
cet-14807	31	21	70	70	NUM
cet-14807	31	22	,	,	PUNCT
cet-14807	31	23	76	76	NUM
cet-14807	31	24	)	)	PUNCT
cet-14807	31	25	and	and	CCONJ
cet-14807	31	26	the	the	DET
cet-14807	31	27	center	center	NOUN
cet-14807	31	28	grid	grid	NOUN
cet-14807	31	29	box	box	PROPN
cet-14807	31	30	coordinates	coordinate	NOUN
cet-14807	31	31	(	(	PUNCT
cet-14807	31	32	-8.972	-8.972	NOUN
cet-14807	31	33	,	,	PUNCT
cet-14807	31	34	4.389	4.389	NUM
cet-14807	31	35	,	,	PUNCT
cet-14807	31	36	-4.444	-4.444	NUM
cet-14807	31	37	)	)	PUNCT
cet-14807	31	38	.	.	PUNCT
cet-14807	32	1	2.3	2.3	NUM
cet-14807	32	2	molecular	molecular	ADJ
cet-14807	32	3	docking	dock	VERB
cet-14807	32	4	the	the	DET
cet-14807	32	5	18	18	NUM
cet-14807	32	6	high	high	ADJ
cet-14807	32	7	scoring	scoring	NOUN
cet-14807	32	8	bioactive	bioactive	ADJ
cet-14807	32	9	components	component	NOUN
cet-14807	32	10	and	and	CCONJ
cet-14807	32	11	ribavirin	ribavirin	NOUN
cet-14807	32	12	were	be	AUX
cet-14807	32	13	docked	dock	VERB
cet-14807	32	14	against	against	ADP
cet-14807	32	15	the	the	DET
cet-14807	32	16	ns2b	ns2b	NOUN
cet-14807	32	17	-	-	PUNCT
cet-14807	32	18	ns3	ns3	NOUN
cet-14807	32	19	protease	protease	NOUN
cet-14807	32	20	(	(	PUNCT
cet-14807	32	21	2fom	2fom	NOUN
cet-14807	32	22	)	)	PUNCT
cet-14807	32	23	using	use	VERB
cet-14807	32	24	autodock	autodock	PROPN
cet-14807	32	25	vina	vina	PROPN
cet-14807	32	26	,	,	PUNCT
cet-14807	32	27	which	which	PRON
cet-14807	32	28	provided	provide	VERB
cet-14807	32	29	3d	3d	NUM
cet-14807	32	30	ligand	ligand	NOUN
cet-14807	32	31	positions	position	NOUN
cet-14807	32	32	and	and	CCONJ
cet-14807	32	33	binding	bind	VERB
cet-14807	32	34	affinity	affinity	NOUN
cet-14807	32	35	results	result	NOUN
cet-14807	32	36	in	in	ADP
cet-14807	32	37	kcal	kcal	PROPN
cet-14807	32	38	/	/	SYM
cet-14807	32	39	mol	mol	PROPN
cet-14807	32	40	(	(	PUNCT
cet-14807	32	41	trott	trott	PROPN
cet-14807	32	42	and	and	CCONJ
cet-14807	32	43	olson	olson	NOUN
cet-14807	32	44	,	,	PUNCT
cet-14807	32	45	2010	2010	NUM
cet-14807	32	46	)	)	PUNCT
cet-14807	32	47	.	.	PUNCT
cet-14807	33	1	pymol	pymol	PROPN
cet-14807	33	2	is	be	AUX
cet-14807	33	3	used	use	VERB
cet-14807	33	4	for	for	ADP
cet-14807	33	5	verification	verification	NOUN
cet-14807	33	6	to	to	PART
cet-14807	33	7	find	find	VERB
cet-14807	33	8	out	out	ADP
cet-14807	33	9	whether	whether	SCONJ
cet-14807	33	10	the	the	DET
cet-14807	33	11	process	process	NOUN
cet-14807	33	12	is	be	AUX
cet-14807	33	13	valid	valid	ADJ
cet-14807	33	14	.	.	PUNCT
cet-14807	34	1	if	if	SCONJ
cet-14807	34	2	the	the	DET
cet-14807	34	3	rmsd	rmsd	NOUN
cet-14807	34	4	results	result	NOUN
cet-14807	34	5	are	be	AUX
cet-14807	34	6	less	less	ADJ
cet-14807	34	7	than	than	ADP
cet-14807	34	8	2å	2å	NUM
cet-14807	34	9	then	then	ADV
cet-14807	34	10	the	the	DET
cet-14807	34	11	parameters	parameter	NOUN
cet-14807	34	12	used	use	VERB
cet-14807	34	13	are	be	AUX
cet-14807	34	14	considered	consider	VERB
cet-14807	34	15	correct	correct	ADJ
cet-14807	34	16	(	(	PUNCT
cet-14807	34	17	ruswanto	ruswanto	NOUN
cet-14807	34	18	et	et	PROPN
cet-14807	34	19	al	al	PROPN
cet-14807	34	20	.	.	PROPN
cet-14807	34	21	,	,	PUNCT
cet-14807	34	22	2022	2022	NUM
cet-14807	34	23	)	)	PUNCT
cet-14807	34	24	.	.	PUNCT
cet-14807	35	1	2.4	2.4	NUM
cet-14807	35	2	scoring	scoring	NOUN
cet-14807	35	3	function	function	NOUN
cet-14807	35	4	and	and	CCONJ
cet-14807	35	5	energy	energy	NOUN
cet-14807	35	6	calculation	calculation	NOUN
cet-14807	35	7	binding	bind	VERB
cet-14807	35	8	energy	energy	NOUN
cet-14807	35	9	is	be	AUX
cet-14807	35	10	based	base	VERB
cet-14807	35	11	on	on	ADP
cet-14807	35	12	gibbs	gibbs	PROPN
cet-14807	35	13	free	free	ADJ
cet-14807	35	14	energy	energy	NOUN
cet-14807	35	15	(	(	PUNCT
cet-14807	35	16	δg	δg	VERB
cet-14807	35	17	in	in	ADP
cet-14807	35	18	kcal	kcal	PROPN
cet-14807	35	19	/	/	SYM
cet-14807	35	20	mol	mol	PROPN
cet-14807	35	21	)	)	PUNCT
cet-14807	35	22	.	.	PUNCT
cet-14807	36	1	an	an	DET
cet-14807	36	2	unfavorable	unfavorable	ADJ
cet-14807	36	3	δg	δg	NOUN
cet-14807	36	4	indicates	indicate	VERB
cet-14807	36	5	a	a	DET
cet-14807	36	6	powerful	powerful	ADJ
cet-14807	36	7	bind	bind	NOUN
cet-14807	36	8	between	between	ADP
cet-14807	36	9	the	the	DET
cet-14807	36	10	ns2b	ns2b	NOUN
cet-14807	36	11	-	-	PUNCT
cet-14807	36	12	ns3	ns3	NOUN
cet-14807	36	13	protease	protease	NOUN
cet-14807	36	14	(	(	PUNCT
cet-14807	36	15	2fom	2fom	NOUN
cet-14807	36	16	)	)	PUNCT
cet-14807	36	17	and	and	CCONJ
cet-14807	36	18	tawa	tawa	PROPN
cet-14807	36	19	-	-	PUNCT
cet-14807	36	20	tawa	tawa	PROPN
cet-14807	36	21	components	component	NOUN
cet-14807	36	22	(	(	PUNCT
cet-14807	36	23	forli	forli	PROPN
cet-14807	36	24	et	et	PROPN
cet-14807	36	25	al	al	PROPN
cet-14807	36	26	.	.	PROPN
cet-14807	36	27	,	,	PUNCT
cet-14807	36	28	2016	2016	NUM
cet-14807	36	29	)	)	PUNCT
cet-14807	36	30	.	.	PUNCT
cet-14807	37	1	the	the	DET
cet-14807	37	2	predicted	predict	VERB
cet-14807	37	3	δg	δg	NOUN
cet-14807	37	4	value	value	NOUN
cet-14807	37	5	comes	come	VERB
cet-14807	37	6	from	from	ADP
cet-14807	37	7	the	the	DET
cet-14807	37	8	scoring	scoring	NOUN
cet-14807	37	9	function	function	NOUN
cet-14807	37	10	eq(1	eq(1	NOUN
cet-14807	37	11	):	):	PUNCT
cet-14807	37	12	(	(	PUNCT
cet-14807	37	13	1	1	X
cet-14807	37	14	)	)	PUNCT
cet-14807	37	15	in	in	ADP
cet-14807	37	16	this	this	DET
cet-14807	37	17	eq(1	eq(1	NOUN
cet-14807	37	18	)	)	PUNCT
cet-14807	37	19	s1	s1	NOUN
cet-14807	37	20	refers	refer	VERB
cet-14807	37	21	to	to	ADP
cet-14807	37	22	the	the	DET
cet-14807	37	23	scoring	scoring	NOUN
cet-14807	37	24	function	function	NOUN
cet-14807	37	25	used	use	VERB
cet-14807	37	26	in	in	ADP
cet-14807	37	27	molecular	molecular	ADJ
cet-14807	37	28	docking	docking	NOUN
cet-14807	37	29	to	to	PART
cet-14807	37	30	calculate	calculate	VERB
cet-14807	37	31	gibbs	gibbs	PROPN
cet-14807	37	32	free	free	ADJ
cet-14807	37	33	energy	energy	NOUN
cet-14807	37	34	change	change	NOUN
cet-14807	37	35	score	score	NOUN
cet-14807	37	36	δ⁰g	δ⁰g	PROPN
cet-14807	37	37	.	.	PUNCT
cet-14807	37	38	where	where	SCONJ
cet-14807	37	39	c1	c1	PROPN
cet-14807	37	40	represents	represent	VERB
cet-14807	37	41	the	the	DET
cet-14807	37	42	conformation	conformation	NOUN
cet-14807	37	43	or	or	CCONJ
cet-14807	37	44	interaction	interaction	NOUN
cet-14807	37	45	resulting	result	VERB
cet-14807	37	46	from	from	ADP
cet-14807	37	47	either	either	CCONJ
cet-14807	37	48	intramolecular	intramolecular	ADJ
cet-14807	37	49	(	(	PUNCT
cet-14807	37	50	cintra1	cintra1	NOUN
cet-14807	37	51	)	)	PUNCT
cet-14807	37	52	or	or	CCONJ
cet-14807	37	53	s1	s1	PROPN
cet-14807	37	54	=	=	SYM
cet-14807	37	55	δ⁰g	δ⁰g	PROPN
cet-14807	37	56	=	=	SYM
cet-14807	37	57	g(c1	g(c1	NOUN
cet-14807	37	58	-	-	PUNCT
cet-14807	37	59	cintra1	cintra1	NOUN
cet-14807	37	60	)	)	PUNCT
cet-14807	37	61	=	=	SYM
cet-14807	37	62	g(cinter1	g(cinter1	PROPN
cet-14807	37	63	)	)	PUNCT
cet-14807	37	64	68	68	NUM
cet-14807	37	65	intermolecular	intermolecular	ADJ
cet-14807	37	66	(	(	PUNCT
cet-14807	37	67	cinter1	cinter1	NOUN
cet-14807	37	68	)	)	PUNCT
cet-14807	37	69	both	both	PRON
cet-14807	37	70	hydrophobic	hydrophobic	ADJ
cet-14807	37	71	reactions	reaction	NOUN
cet-14807	37	72	and	and	CCONJ
cet-14807	37	73	hydrogen	hydrogen	NOUN
cet-14807	37	74	bonds	bond	NOUN
cet-14807	37	75	,	,	PUNCT
cet-14807	37	76	and	and	CCONJ
cet-14807	37	77	g	g	NOUN
cet-14807	37	78	is	be	AUX
cet-14807	37	79	a	a	DET
cet-14807	37	80	non	non	ADJ
cet-14807	37	81	-	-	ADJ
cet-14807	37	82	linear	linear	ADJ
cet-14807	37	83	function	function	NOUN
cet-14807	37	84	(	(	PUNCT
cet-14807	37	85	sukmanadi	sukmanadi	NOUN
cet-14807	37	86	and	and	CCONJ
cet-14807	37	87	mustofa	mustofa	NOUN
cet-14807	37	88	,	,	PUNCT
cet-14807	37	89	2021	2021	NUM
cet-14807	37	90	)	)	PUNCT
cet-14807	37	91	.	.	PUNCT
cet-14807	38	1	2.5	2.5	NUM
cet-14807	38	2	adme	adme	NOUN
cet-14807	38	3	and	and	CCONJ
cet-14807	38	4	toxicity	toxicity	NOUN
cet-14807	38	5	analysis	analysis	NOUN
cet-14807	38	6	the	the	DET
cet-14807	38	7	18	18	NUM
cet-14807	38	8	high	high	ADJ
cet-14807	38	9	scoring	scoring	NOUN
cet-14807	38	10	bioactive	bioactive	ADJ
cet-14807	38	11	components	component	NOUN
cet-14807	38	12	were	be	AUX
cet-14807	38	13	used	use	VERB
cet-14807	38	14	to	to	PART
cet-14807	38	15	predict	predict	VERB
cet-14807	38	16	druglikeness	druglikeness	NOUN
cet-14807	38	17	using	use	VERB
cet-14807	38	18	the	the	DET
cet-14807	38	19	swissadme	swissadme	NOUN
cet-14807	38	20	’s	’s	PART
cet-14807	38	21	lipinski	lipinski	PROPN
cet-14807	38	22	rule	rule	NOUN
cet-14807	38	23	and	and	CCONJ
cet-14807	38	24	toxicity	toxicity	NOUN
cet-14807	38	25	using	use	VERB
cet-14807	38	26	admetsar	admetsar	ADJ
cet-14807	38	27	.	.	PUNCT
cet-14807	39	1	3	3	X
cet-14807	39	2	.	.	X
cet-14807	39	3	results	result	NOUN
cet-14807	39	4	and	and	CCONJ
cet-14807	39	5	discussion	discussion	NOUN
cet-14807	39	6	molecular	molecular	ADJ
cet-14807	39	7	docking	docking	NOUN
cet-14807	39	8	,	,	PUNCT
cet-14807	39	9	adme	adme	NOUN
cet-14807	39	10	predictions	prediction	NOUN
cet-14807	39	11	,	,	PUNCT
cet-14807	39	12	and	and	CCONJ
cet-14807	39	13	toxicity	toxicity	NOUN
cet-14807	39	14	analysis	analysis	NOUN
cet-14807	39	15	was	be	AUX
cet-14807	39	16	carried	carry	VERB
cet-14807	39	17	out	out	ADP
cet-14807	39	18	on	on	ADP
cet-14807	39	19	tawa	tawa	PROPN
cet-14807	39	20	-	-	PUNCT
cet-14807	39	21	tawa	tawa	PROPN
cet-14807	39	22	bioactive	bioactive	ADJ
cet-14807	39	23	compounds	compound	NOUN
cet-14807	39	24	(	(	PUNCT
cet-14807	39	25	euphorbia	euphorbia	PROPN
cet-14807	39	26	hirta	hirta	PROPN
cet-14807	39	27	l.	l.	PROPN
cet-14807	39	28	)	)	PUNCT
cet-14807	39	29	against	against	ADP
cet-14807	39	30	the	the	DET
cet-14807	39	31	ns2b	ns2b	NOUN
cet-14807	39	32	-	-	PUNCT
cet-14807	39	33	ns3	ns3	NOUN
cet-14807	39	34	protease	protease	NOUN
cet-14807	39	35	of	of	ADP
cet-14807	39	36	denv-2	denv-2	PROPN
cet-14807	39	37	.	.	PUNCT
cet-14807	40	1	the	the	DET
cet-14807	40	2	bioactive	bioactive	PROPN
cet-14807	40	3	components	component	NOUN
cet-14807	40	4	docking	dock	VERB
cet-14807	40	5	score	score	NOUN
cet-14807	40	6	and	and	CCONJ
cet-14807	40	7	binding	bind	VERB
cet-14807	40	8	features	feature	NOUN
cet-14807	40	9	is	be	AUX
cet-14807	40	10	shown	show	VERB
cet-14807	40	11	in	in	ADP
cet-14807	40	12	table	table	NOUN
cet-14807	40	13	2	2	NUM
cet-14807	40	14	.	.	PUNCT
cet-14807	41	1	the	the	DET
cet-14807	41	2	docking	docking	NOUN
cet-14807	41	3	scores	score	NOUN
cet-14807	41	4	ranged	range	VERB
cet-14807	41	5	from	from	ADP
cet-14807	41	6	-10.50	-10.50	PROPN
cet-14807	41	7	to	to	ADP
cet-14807	41	8	-5.76	-5.76	ADJ
cet-14807	41	9	kcal	kcal	NOUN
cet-14807	41	10	/	/	SYM
cet-14807	41	11	mol	mol	NOUN
cet-14807	41	12	and	and	CCONJ
cet-14807	41	13	all	all	DET
cet-14807	41	14	compounds	compound	NOUN
cet-14807	41	15	have	have	VERB
cet-14807	41	16	higher	high	ADJ
cet-14807	41	17	binding	bind	VERB
cet-14807	41	18	affinity	affinity	NOUN
cet-14807	41	19	than	than	ADP
cet-14807	41	20	the	the	DET
cet-14807	41	21	control	control	NOUN
cet-14807	41	22	drug	drug	NOUN
cet-14807	41	23	ribavirin	ribavirin	NOUN
cet-14807	41	24	.	.	PUNCT
cet-14807	42	1	using	use	VERB
cet-14807	42	2	ligplot+	ligplot+	PART
cet-14807	42	3	hydrogen	hydrogen	NOUN
cet-14807	42	4	bond	bond	NOUN
cet-14807	42	5	interactions	interaction	NOUN
cet-14807	42	6	of	of	ADP
cet-14807	42	7	euphorbia	euphorbia	ADJ
cet-14807	42	8	hirta	hirta	PROPN
cet-14807	42	9	l.	l.	PROPN
cet-14807	42	10	with	with	ADP
cet-14807	42	11	2fom	2fom	PROPN
cet-14807	42	12	amino	amino	NOUN
cet-14807	42	13	acid	acid	NOUN
cet-14807	42	14	residues	residue	NOUN
cet-14807	42	15	was	be	AUX
cet-14807	42	16	discovered	discover	VERB
cet-14807	42	17	.	.	PUNCT
cet-14807	43	1	the	the	DET
cet-14807	43	2	hydrogen	hydrogen	NOUN
cet-14807	43	3	bonds	bond	NOUN
cet-14807	43	4	are	be	AUX
cet-14807	43	5	formed	form	VERB
cet-14807	43	6	with	with	ADP
cet-14807	43	7	gly153	gly153	PROPN
cet-14807	43	8	,	,	PUNCT
cet-14807	43	9	gly151	gly151	PROPN
cet-14807	43	10	,	,	PUNCT
cet-14807	43	11	asp75	asp75	ADJ
cet-14807	43	12	,	,	PUNCT
cet-14807	43	13	trp50	trp50	ADJ
cet-14807	43	14	,	,	PUNCT
cet-14807	43	15	his51	his51	NOUN
cet-14807	43	16	,	,	PUNCT
cet-14807	43	17	val155	val155	PROPN
cet-14807	43	18	,	,	PUNCT
cet-14807	43	19	ser135	ser135	PROPN
cet-14807	43	20	,	,	PUNCT
cet-14807	43	21	thr120	thr120	PROPN
cet-14807	43	22	,	,	PUNCT
cet-14807	43	23	asn119	asn119	PROPN
cet-14807	43	24	,	,	PUNCT
cet-14807	43	25	asp17	asp17	ADP
cet-14807	43	26	,	,	PUNCT
cet-14807	43	27	and	and	CCONJ
cet-14807	43	28	asn152	asn152	PROPN
cet-14807	43	29	.	.	PUNCT
cet-14807	44	1	the	the	DET
cet-14807	44	2	18	18	NUM
cet-14807	44	3	bioactive	bioactive	ADJ
cet-14807	44	4	components	component	NOUN
cet-14807	44	5	and	and	CCONJ
cet-14807	44	6	the	the	DET
cet-14807	44	7	control	control	NOUN
cet-14807	44	8	drug	drug	NOUN
cet-14807	44	9	ribavirin	ribavirin	NOUN
cet-14807	44	10	interacted	interact	VERB
cet-14807	44	11	with	with	ADP
cet-14807	44	12	the	the	DET
cet-14807	44	13	catalytic	catalytic	ADJ
cet-14807	44	14	triad	triad	ADJ
cet-14807	44	15	his-51	his-51	NOUN
cet-14807	44	16	,	,	PUNCT
cet-14807	44	17	asp-75	asp-75	PROPN
cet-14807	44	18	,	,	PUNCT
cet-14807	44	19	and	and	CCONJ
cet-14807	44	20	ser-135	ser-135	VERB
cet-14807	44	21	via	via	ADP
cet-14807	44	22	hydrogen	hydrogen	NOUN
cet-14807	44	23	bonding	bonding	NOUN
cet-14807	44	24	or	or	CCONJ
cet-14807	44	25	hydrophobic	hydrophobic	NOUN
cet-14807	44	26	contacts	contact	NOUN
cet-14807	44	27	.	.	PUNCT
cet-14807	45	1	table	table	NOUN
cet-14807	45	2	2	2	NUM
cet-14807	45	3	:	:	PUNCT
cet-14807	45	4	ns2b	ns2b	NOUN
cet-14807	45	5	-	-	PUNCT
cet-14807	45	6	ns3	ns3	NOUN
cet-14807	45	7	protease	protease	NOUN
cet-14807	45	8	(	(	PUNCT
cet-14807	45	9	2fom	2fom	NOUN
cet-14807	45	10	)	)	PUNCT
cet-14807	45	11	and	and	CCONJ
cet-14807	45	12	euphorbia	euphorbia	PROPN
cet-14807	45	13	hirta	hirta	PROPN
cet-14807	45	14	l.	l.	PROPN
cet-14807	45	15	calculated	calculate	VERB
cet-14807	45	16	docking	docking	NOUN
cet-14807	45	17	score	score	NOUN
cet-14807	45	18	(	(	PUNCT
cet-14807	45	19	in	in	ADP
cet-14807	45	20	kcal	kcal	PROPN
cet-14807	45	21	/	/	SYM
cet-14807	45	22	mol	mol	NOUN
cet-14807	45	23	)	)	PUNCT
cet-14807	45	24	and	and	CCONJ
cet-14807	45	25	interactions	interaction	NOUN
cet-14807	45	26	based	base	VERB
cet-14807	45	27	on	on	ADP
cet-14807	45	28	hydrogen	hydrogen	NOUN
cet-14807	45	29	bond	bond	NOUN
cet-14807	45	30	analysis	analysis	NOUN
cet-14807	45	31	.	.	PUNCT
cet-14807	46	1	compound	compound	NOUN
cet-14807	46	2	docking	docking	NOUN
cet-14807	46	3	score	score	NOUN
cet-14807	46	4	(	(	PUNCT
cet-14807	46	5	kcal	kcal	NOUN
cet-14807	46	6	/	/	SYM
cet-14807	46	7	mol	mol	NOUN
cet-14807	46	8	)	)	PUNCT
cet-14807	46	9	binding	bind	VERB
cet-14807	46	10	features	feature	NOUN
cet-14807	46	11	(	(	PUNCT
cet-14807	46	12	hydrogen	hydrogen	NOUN
cet-14807	46	13	bond	bond	NOUN
cet-14807	46	14	in	in	ADP
cet-14807	46	15	å	å	NOUN
cet-14807	46	16	)	)	PUNCT
cet-14807	46	17	compound	compound	NOUN
cet-14807	46	18	docking	docking	NOUN
cet-14807	46	19	score	score	NOUN
cet-14807	46	20	(	(	PUNCT
cet-14807	46	21	kcal	kcal	NOUN
cet-14807	46	22	/	/	SYM
cet-14807	46	23	mol	mol	NOUN
cet-14807	46	24	)	)	PUNCT
cet-14807	46	25	binding	bind	VERB
cet-14807	46	26	features	feature	NOUN
cet-14807	46	27	(	(	PUNCT
cet-14807	46	28	hydrogen	hydrogen	NOUN
cet-14807	46	29	bond	bond	NOUN
cet-14807	46	30	in	in	ADP
cet-14807	46	31	å	å	NOUN
cet-14807	46	32	)	)	PUNCT
cet-14807	46	33	corchoionoside	corchoionoside	NOUN
cet-14807	46	34	c	c	PROPN
cet-14807	46	35	-10.50	-10.50	PROPN
cet-14807	46	36	gly153	gly153	PROPN
cet-14807	46	37	(	(	PUNCT
cet-14807	46	38	3.13	3.13	NUM
cet-14807	46	39	å	å	NOUN
cet-14807	46	40	)	)	PUNCT
cet-14807	46	41	brevifolin	brevifolin	NOUN
cet-14807	46	42	carboxylic	carboxylic	ADJ
cet-14807	46	43	acid	acid	NOUN
cet-14807	46	44	-7.64	-7.64	NUM
cet-14807	46	45	gly153	gly153	PROPN
cet-14807	46	46	(	(	PUNCT
cet-14807	46	47	3.07	3.07	NUM
cet-14807	46	48	å	å	NOUN
cet-14807	46	49	)	)	PUNCT
cet-14807	46	50	,	,	PUNCT
cet-14807	46	51	(	(	PUNCT
cet-14807	46	52	3.11	3.11	NUM
cet-14807	46	53	å	å	NOUN
cet-14807	46	54	)	)	PUNCT
cet-14807	46	55	luteolin-7	luteolin-7	PROPN
cet-14807	46	56	-	-	PUNCT
cet-14807	46	57	o	o	NOUN
cet-14807	46	58	-	-	ADJ
cet-14807	46	59	betad	betad	ADJ
cet-14807	46	60	-	-	PUNCT
cet-14807	46	61	glucopyranoside	glucopyranoside	NOUN
cet-14807	46	62	-9.05	-9.05	NOUN
cet-14807	46	63	val155	val155	PROPN
cet-14807	46	64	(	(	PUNCT
cet-14807	46	65	3.14	3.14	NUM
cet-14807	46	66	)	)	PUNCT
cet-14807	46	67	,	,	PUNCT
cet-14807	46	68	his51	his51	NOUN
cet-14807	46	69	(	(	PUNCT
cet-14807	46	70	2.96	2.96	NUM
cet-14807	46	71	å	å	NOUN
cet-14807	46	72	)	)	PUNCT
cet-14807	46	73	,	,	PUNCT
cet-14807	46	74	(	(	PUNCT
cet-14807	46	75	2.67	2.67	NUM
cet-14807	46	76	å	å	NOUN
cet-14807	46	77	)	)	PUNCT
cet-14807	46	78	,	,	PUNCT
cet-14807	46	79	(	(	PUNCT
cet-14807	46	80	2.86	2.86	NUM
cet-14807	46	81	å	å	NOUN
cet-14807	46	82	)	)	PUNCT
cet-14807	46	83	24hydroperoxycycloart25	24hydroperoxycycloart25	PROPN
cet-14807	46	84	-	-	PUNCT
cet-14807	46	85	en-3beta	en-3beta	PROPN
cet-14807	46	86	-	-	PUNCT
cet-14807	46	87	ol	ol	PROPN
cet-14807	46	88	-7.58	-7.58	NOUN
cet-14807	46	89	asn119	asn119	PROPN
cet-14807	46	90	(	(	PUNCT
cet-14807	46	91	3.13	3.13	NUM
cet-14807	46	92	å	å	NOUN
cet-14807	46	93	)	)	PUNCT
cet-14807	46	94	,	,	PUNCT
cet-14807	46	95	gly153	gly153	PROPN
cet-14807	46	96	(	(	PUNCT
cet-14807	46	97	2.91	2.91	NUM
cet-14807	46	98	å	å	NOUN
cet-14807	46	99	)	)	PUNCT
cet-14807	46	100	ellagic	ellagic	ADJ
cet-14807	46	101	acid	acid	NOUN
cet-14807	46	102	-8.85	-8.85	NOUN
cet-14807	47	1	gly153(3.28	gly153(3.28	PROPN
cet-14807	48	1	å	å	NOUN
cet-14807	48	2	)	)	PUNCT
cet-14807	48	3	2	2	NUM
cet-14807	48	4	-	-	PUNCT
cet-14807	48	5	coumaroylquinic	coumaroylquinic	ADJ
cet-14807	48	6	acid	acid	NOUN
cet-14807	48	7	-7.55	-7.55	NUM
cet-14807	48	8	thr120	thr120	NOUN
cet-14807	48	9	(	(	PUNCT
cet-14807	48	10	2.95	2.95	NUM
cet-14807	48	11	å	å	NOUN
cet-14807	48	12	)	)	PUNCT
cet-14807	48	13	,	,	PUNCT
cet-14807	48	14	asn119	asn119	PROPN
cet-14807	48	15	(	(	PUNCT
cet-14807	48	16	3.14	3.14	NUM
cet-14807	48	17	å	å	NOUN
cet-14807	48	18	)	)	PUNCT
cet-14807	48	19	,	,	PUNCT
cet-14807	48	20	his51	his51	NOUN
cet-14807	48	21	(	(	PUNCT
cet-14807	48	22	3.18	3.18	NUM
cet-14807	48	23	å	å	NOUN
cet-14807	48	24	)	)	PUNCT
cet-14807	48	25	,	,	PUNCT
cet-14807	48	26	(	(	PUNCT
cet-14807	48	27	2.57	2.57	NUM
cet-14807	48	28	å	å	NOUN
cet-14807	48	29	)	)	PUNCT
cet-14807	48	30	,	,	PUNCT
cet-14807	48	31	(	(	PUNCT
cet-14807	48	32	2.89	2.89	NUM
cet-14807	48	33	å	å	NOUN
cet-14807	48	34	)	)	PUNCT
cet-14807	48	35	corilagin	corilagin	NOUN
cet-14807	48	36	-8.55	-8.55	NUM
cet-14807	48	37	gly153	gly153	PROPN
cet-14807	48	38	(	(	PUNCT
cet-14807	48	39	3.18	3.18	NUM
cet-14807	48	40	å	å	NOUN
cet-14807	48	41	)	)	PUNCT
cet-14807	48	42	,	,	PUNCT
cet-14807	48	43	trp50	trp50	PROPN
cet-14807	48	44	(	(	PUNCT
cet-14807	48	45	3.12	3.12	NUM
cet-14807	48	46	å	å	NOUN
cet-14807	48	47	)	)	PUNCT
cet-14807	48	48	isojaponin	isojaponin	NOUN
cet-14807	48	49	a	a	DET
cet-14807	48	50	-6.80	-6.80	NOUN
cet-14807	48	51	ser135	ser135	PROPN
cet-14807	48	52	(	(	PUNCT
cet-14807	48	53	2.92	2.92	NUM
cet-14807	48	54	å	å	NOUN
cet-14807	48	55	)	)	PUNCT
cet-14807	48	56	,	,	PUNCT
cet-14807	48	57	his51	his51	NOUN
cet-14807	48	58	(	(	PUNCT
cet-14807	48	59	3.00	3.00	NUM
cet-14807	48	60	å	å	NOUN
cet-14807	48	61	)	)	PUNCT
cet-14807	48	62	,	,	PUNCT
cet-14807	48	63	asp75	asp75	PROPN
cet-14807	48	64	(	(	PUNCT
cet-14807	48	65	2.57	2.57	NUM
cet-14807	48	66	å	å	NOUN
cet-14807	48	67	)	)	PUNCT
cet-14807	48	68	cycloart-23	cycloart-23	NOUN
cet-14807	48	69	-	-	PUNCT
cet-14807	48	70	ene3beta,25	ene3beta,25	NOUN
cet-14807	48	71	-	-	PUNCT
cet-14807	48	72	diol	diol	NOUN
cet-14807	48	73	-8.49	-8.49	X
cet-14807	48	74	asp17	asp17	PROPN
cet-14807	48	75	(	(	PUNCT
cet-14807	48	76	2.57	2.57	NUM
cet-14807	48	77	å	å	NOUN
cet-14807	48	78	)	)	PUNCT
cet-14807	48	79	,	,	PUNCT
cet-14807	48	80	(	(	PUNCT
cet-14807	48	81	2.86	2.86	NUM
cet-14807	48	82	å	å	NOUN
cet-14807	48	83	)	)	PUNCT
cet-14807	48	84	syringin	syringin	VERB
cet-14807	48	85	-6.61	-6.61	NOUN
cet-14807	48	86	thr120	thr120	PROPN
cet-14807	48	87	(	(	PUNCT
cet-14807	48	88	2.99	2.99	NUM
cet-14807	48	89	å	å	NOUN
cet-14807	48	90	)	)	PUNCT
cet-14807	48	91	kaempferol-3	kaempferol-3	PROPN
cet-14807	48	92	-	-	PUNCT
cet-14807	48	93	oglucuronide	oglucuronide	NOUN
cet-14807	48	94	-8.37	-8.37	PROPN
cet-14807	48	95	his51	his51	NOUN
cet-14807	48	96	(	(	PUNCT
cet-14807	48	97	2.98	2.98	NUM
cet-14807	48	98	å	å	NOUN
cet-14807	48	99	)	)	PUNCT
cet-14807	48	100	,	,	PUNCT
cet-14807	48	101	(	(	PUNCT
cet-14807	48	102	2.86	2.86	NUM
cet-14807	48	103	å	å	NOUN
cet-14807	48	104	)	)	PUNCT
cet-14807	48	105	feruloyl	feruloyl	ADJ
cet-14807	48	106	malate	malate	NOUN
cet-14807	48	107	-6.41	-6.41	PUNCT
cet-14807	49	1	gyl153	gyl153	PROPN
cet-14807	49	2	(	(	PUNCT
cet-14807	49	3	3.14	3.14	NUM
cet-14807	49	4	å	å	NOUN
cet-14807	49	5	)	)	PUNCT
cet-14807	49	6	trigallic	trigallic	ADJ
cet-14807	49	7	acid	acid	PROPN
cet-14807	49	8	-8.32	-8.32	NUM
cet-14807	49	9	his51	his51	NOUN
cet-14807	49	10	(	(	PUNCT
cet-14807	49	11	3.12	3.12	NUM
cet-14807	49	12	å	å	NOUN
cet-14807	49	13	)	)	PUNCT
cet-14807	49	14	,	,	PUNCT
cet-14807	49	15	(	(	PUNCT
cet-14807	49	16	2.57	2.57	NUM
cet-14807	49	17	å	å	NOUN
cet-14807	49	18	)	)	PUNCT
cet-14807	49	19	,	,	PUNCT
cet-14807	49	20	(	(	PUNCT
cet-14807	49	21	2.86	2.86	NUM
cet-14807	49	22	å	å	NOUN
cet-14807	49	23	)	)	PUNCT
cet-14807	49	24	,	,	PUNCT
cet-14807	49	25	gly153	gly153	PROPN
cet-14807	49	26	(	(	PUNCT
cet-14807	49	27	2.94	2.94	NUM
cet-14807	49	28	å	å	NOUN
cet-14807	49	29	)	)	PUNCT
cet-14807	49	30	,	,	PUNCT
cet-14807	49	31	val155	val155	PROPN
cet-14807	49	32	(	(	PUNCT
cet-14807	49	33	2.91	2.91	NUM
cet-14807	49	34	å	å	NOUN
cet-14807	49	35	)	)	PUNCT
cet-14807	49	36	tyrosylglutamate	tyrosylglutamate	ADJ
cet-14807	49	37	-6.37	-6.37	PROPN
cet-14807	49	38	gly151	gly151	PROPN
cet-14807	49	39	(	(	PUNCT
cet-14807	49	40	2.80	2.80	NUM
cet-14807	49	41	å	å	NOUN
cet-14807	49	42	)	)	PUNCT
cet-14807	49	43	,	,	PUNCT
cet-14807	49	44	asp75	asp75	PROPN
cet-14807	49	45	(	(	PUNCT
cet-14807	49	46	2.96	2.96	NUM
cet-14807	49	47	å	å	NOUN
cet-14807	49	48	)	)	PUNCT
cet-14807	49	49	hyperoside	hyperoside	NOUN
cet-14807	49	50	-8.19	-8.19	X
cet-14807	49	51	his51	his51	NOUN
cet-14807	49	52	(	(	PUNCT
cet-14807	49	53	2.96	2.96	NUM
cet-14807	49	54	å	å	NOUN
cet-14807	49	55	)	)	PUNCT
cet-14807	49	56	,	,	PUNCT
cet-14807	49	57	(	(	PUNCT
cet-14807	49	58	2.57	2.57	NUM
cet-14807	49	59	å	å	NOUN
cet-14807	49	60	)	)	PUNCT
cet-14807	49	61	,	,	PUNCT
cet-14807	49	62	(	(	PUNCT
cet-14807	49	63	2.86	2.86	NUM
cet-14807	49	64	å	å	NOUN
cet-14807	49	65	)	)	PUNCT
cet-14807	49	66	,	,	PUNCT
cet-14807	49	67	gly153	gly153	PROPN
cet-14807	49	68	(	(	PUNCT
cet-14807	49	69	3.30	3.30	NUM
cet-14807	49	70	å	å	NOUN
cet-14807	49	71	)	)	PUNCT
cet-14807	49	72	,	,	PUNCT
cet-14807	49	73	(	(	PUNCT
cet-14807	49	74	2.09	2.09	NUM
cet-14807	49	75	å	å	NOUN
cet-14807	49	76	)	)	PUNCT
cet-14807	49	77	tryptophan	tryptophan	NOUN
cet-14807	49	78	-5.80	-5.80	X
cet-14807	49	79	asn152	asn152	PROPN
cet-14807	49	80	(	(	PUNCT
cet-14807	49	81	3.06	3.06	NUM
cet-14807	49	82	å	å	NOUN
cet-14807	49	83	)	)	PUNCT
cet-14807	49	84	epicatechin	epicatechin	NOUN
cet-14807	49	85	-8.10	-8.10	X
cet-14807	49	86	gly153	gly153	PROPN
cet-14807	49	87	(	(	PUNCT
cet-14807	49	88	3.07	3.07	NUM
cet-14807	49	89	å	å	NOUN
cet-14807	49	90	)	)	PUNCT
cet-14807	49	91	,	,	PUNCT
cet-14807	49	92	(	(	PUNCT
cet-14807	49	93	3.11	3.11	NUM
cet-14807	49	94	å	å	NOUN
cet-14807	49	95	)	)	PUNCT
cet-14807	49	96	chelidonic	chelidonic	ADJ
cet-14807	49	97	acid	acid	NOUN
cet-14807	49	98	-5.76	-5.76	ADJ
cet-14807	49	99	gly151	gly151	PROPN
cet-14807	49	100	(	(	PUNCT
cet-14807	49	101	3.16	3.16	NUM
cet-14807	49	102	å	å	NOUN
cet-14807	49	103	)	)	PUNCT
cet-14807	49	104	ribavirin	ribavirin	NOUN
cet-14807	49	105	-5.41	-5.41	NOUN
cet-14807	49	106	his51	his51	NOUN
cet-14807	49	107	(	(	PUNCT
cet-14807	49	108	3.05	3.05	NUM
cet-14807	49	109	å	å	NOUN
cet-14807	49	110	)	)	PUNCT
cet-14807	49	111	,	,	PUNCT
cet-14807	49	112	arg54	arg54	PROPN
cet-14807	49	113	(	(	PUNCT
cet-14807	49	114	3.18	3.18	NUM
cet-14807	49	115	å	å	NOUN
cet-14807	49	116	)	)	PUNCT
cet-14807	49	117	three	three	NUM
cet-14807	49	118	bioactive	bioactive	ADJ
cet-14807	49	119	components	component	NOUN
cet-14807	49	120	,	,	PUNCT
cet-14807	49	121	including	include	VERB
cet-14807	49	122	corchoionoside	corchoionoside	NOUN
cet-14807	49	123	c	c	NOUN
cet-14807	49	124	,	,	PUNCT
cet-14807	49	125	luteolin-7	luteolin-7	NOUN
cet-14807	49	126	-	-	PUNCT
cet-14807	49	127	o	o	NOUN
cet-14807	49	128	-	-	ADJ
cet-14807	49	129	beta	beta	NOUN
cet-14807	49	130	-	-	PUNCT
cet-14807	49	131	d	d	NOUN
cet-14807	49	132	-	-	PUNCT
cet-14807	49	133	glucopyranoside	glucopyranoside	NOUN
cet-14807	49	134	,	,	PUNCT
cet-14807	49	135	and	and	CCONJ
cet-14807	49	136	ellagic	ellagic	ADJ
cet-14807	49	137	acid	acid	NOUN
cet-14807	49	138	show	show	NOUN
cet-14807	49	139	promising	promise	VERB
cet-14807	49	140	binding	bind	VERB
cet-14807	49	141	affinities	affinity	NOUN
cet-14807	49	142	.	.	PUNCT
cet-14807	50	1	several	several	ADJ
cet-14807	50	2	hydrogen	hydrogen	NOUN
cet-14807	50	3	bonds	bond	NOUN
cet-14807	50	4	are	be	AUX
cet-14807	50	5	formed	form	VERB
cet-14807	50	6	in	in	ADP
cet-14807	50	7	the	the	DET
cet-14807	50	8	active	active	ADJ
cet-14807	50	9	site	site	NOUN
cet-14807	50	10	between	between	ADP
cet-14807	50	11	the	the	DET
cet-14807	50	12	hydroxyl	hydroxyl	NOUN
cet-14807	50	13	and	and	CCONJ
cet-14807	50	14	carbonyl	carbonyl	NOUN
cet-14807	50	15	groups	group	NOUN
cet-14807	50	16	of	of	ADP
cet-14807	50	17	these	these	DET
cet-14807	50	18	phytochemicals	phytochemical	NOUN
cet-14807	50	19	and	and	CCONJ
cet-14807	50	20	the	the	DET
cet-14807	50	21	residues	residue	NOUN
cet-14807	50	22	of	of	ADP
cet-14807	50	23	various	various	ADJ
cet-14807	50	24	amino	amino	ADJ
cet-14807	50	25	acids	acid	NOUN
cet-14807	50	26	.	.	PUNCT
cet-14807	51	1	another	another	DET
cet-14807	51	2	three	three	NUM
cet-14807	51	3	bioactive	bioactive	ADJ
cet-14807	51	4	components	component	NOUN
cet-14807	51	5	,	,	PUNCT
cet-14807	51	6	hyperoside	hyperoside	ADV
cet-14807	51	7	,	,	PUNCT
cet-14807	51	8	corilagin	corilagin	NOUN
cet-14807	51	9	,	,	PUNCT
cet-14807	51	10	and	and	CCONJ
cet-14807	51	11	kaempferol-3	kaempferol-3	PROPN
cet-14807	51	12	-	-	PUNCT
cet-14807	51	13	o	o	NOUN
cet-14807	51	14	-	-	ADJ
cet-14807	51	15	glucuronide	glucuronide	ADJ
cet-14807	51	16	,	,	PUNCT
cet-14807	51	17	also	also	ADV
cet-14807	51	18	exhibit	exhibit	VERB
cet-14807	51	19	high	high	ADJ
cet-14807	51	20	binding	bind	VERB
cet-14807	51	21	affinities	affinity	NOUN
cet-14807	51	22	to	to	ADP
cet-14807	51	23	the	the	DET
cet-14807	51	24	protease	protease	NOUN
cet-14807	51	25	with	with	ADP
cet-14807	51	26	the	the	DET
cet-14807	51	27	formation	formation	NOUN
cet-14807	51	28	of	of	ADP
cet-14807	51	29	hydrogen	hydrogen	NOUN
cet-14807	51	30	bonding	bonding	NOUN
cet-14807	51	31	and	and	CCONJ
cet-14807	51	32	hydrophobic	hydrophobic	NOUN
cet-14807	51	33	bonding	bonding	NOUN
cet-14807	51	34	to	to	ADP
cet-14807	51	35	the	the	DET
cet-14807	51	36	oxygen	oxygen	NOUN
cet-14807	51	37	and	and	CCONJ
cet-14807	51	38	nitrogen	nitrogen	NOUN
cet-14807	51	39	atoms	atom	NOUN
cet-14807	51	40	of	of	ADP
cet-14807	51	41	the	the	DET
cet-14807	51	42	bioactive	bioactive	ADJ
cet-14807	51	43	components	component	NOUN
cet-14807	51	44	and	and	CCONJ
cet-14807	51	45	2fom	2fom	NOUN
cet-14807	51	46	itself	itself	PRON
cet-14807	51	47	.	.	PUNCT
cet-14807	52	1	corchoionoside	corchoionoside	PROPN
cet-14807	52	2	c	c	PROPN
cet-14807	52	3	and	and	CCONJ
cet-14807	52	4	ellagic	ellagic	PROPN
cet-14807	52	5	acid	acid	NOUN
cet-14807	52	6	exhibited	exhibit	VERB
cet-14807	52	7	a	a	DET
cet-14807	52	8	binding	bind	VERB
cet-14807	52	9	affinity	affinity	NOUN
cet-14807	52	10	of	of	ADP
cet-14807	52	11	–	–	PUNCT
cet-14807	52	12	10.50	10.50	NUM
cet-14807	52	13	kcal	kcal	NOUN
cet-14807	52	14	/	/	SYM
cet-14807	52	15	mol	mol	PROPN
cet-14807	52	16	and	and	CCONJ
cet-14807	52	17	–	–	PUNCT
cet-14807	52	18	8.85	8.85	NUM
cet-14807	52	19	kcal	kcal	NOUN
cet-14807	52	20	/	/	SYM
cet-14807	52	21	mol	mol	NOUN
cet-14807	52	22	that	that	PRON
cet-14807	52	23	inhibits	inhibit	VERB
cet-14807	52	24	the	the	DET
cet-14807	52	25	ser-135	ser-135	ADJ
cet-14807	52	26	amino	amino	NOUN
cet-14807	52	27	acid	acid	NOUN
cet-14807	52	28	through	through	ADP
cet-14807	52	29	hydrogen	hydrogen	NOUN
cet-14807	52	30	69	69	NUM
cet-14807	52	31	bonding	bonding	NOUN
cet-14807	52	32	.	.	PUNCT
cet-14807	53	1	luteolin-7	luteolin-7	NOUN
cet-14807	53	2	-	-	PUNCT
cet-14807	53	3	o	o	NOUN
cet-14807	53	4	-	-	ADJ
cet-14807	53	5	beta	beta	NOUN
cet-14807	53	6	-	-	PUNCT
cet-14807	53	7	d	d	NOUN
cet-14807	53	8	-	-	PUNCT
cet-14807	53	9	glucopyranoside	glucopyranoside	NOUN
cet-14807	53	10	showed	show	VERB
cet-14807	53	11	a	a	DET
cet-14807	53	12	binding	bind	VERB
cet-14807	53	13	affinity	affinity	NOUN
cet-14807	53	14	of	of	ADP
cet-14807	53	15	–	–	PUNCT
cet-14807	53	16	9.05	9.05	NUM
cet-14807	53	17	kcal	kcal	NOUN
cet-14807	53	18	/	/	SYM
cet-14807	53	19	mol	mol	NOUN
cet-14807	53	20	that	that	PRON
cet-14807	53	21	inhibits	inhibit	VERB
cet-14807	53	22	the	the	DET
cet-14807	53	23	catalytic	catalytic	ADJ
cet-14807	53	24	triad	triad	PROPN
cet-14807	53	25	(	(	PUNCT
cet-14807	53	26	asp-75	asp-75	PROPN
cet-14807	53	27	,	,	PUNCT
cet-14807	53	28	his-51	his-51	NOUN
cet-14807	53	29	,	,	PUNCT
cet-14807	53	30	and	and	CCONJ
cet-14807	53	31	ser-135	ser-135	VERB
cet-14807	53	32	)	)	PUNCT
cet-14807	53	33	due	due	ADP
cet-14807	53	34	to	to	ADP
cet-14807	53	35	its	its	PRON
cet-14807	53	36	abundance	abundance	NOUN
cet-14807	53	37	of	of	ADP
cet-14807	53	38	oxygen	oxygen	NOUN
cet-14807	53	39	atoms	atom	NOUN
cet-14807	53	40	present	present	ADJ
cet-14807	53	41	in	in	ADP
cet-14807	53	42	the	the	DET
cet-14807	53	43	bioactive	bioactive	PROPN
cet-14807	53	44	component	component	NOUN
cet-14807	53	45	that	that	PRON
cet-14807	53	46	binds	bind	VERB
cet-14807	53	47	to	to	ADP
cet-14807	53	48	the	the	DET
cet-14807	53	49	catalytic	catalytic	ADJ
cet-14807	53	50	triad	triad	NOUN
cet-14807	53	51	.	.	PUNCT
cet-14807	54	1	corilagin	corilagin	PROPN
cet-14807	54	2	showed	show	VERB
cet-14807	54	3	a	a	DET
cet-14807	54	4	binding	bind	VERB
cet-14807	54	5	affinity	affinity	NOUN
cet-14807	54	6	of	of	ADP
cet-14807	54	7	–	–	PUNCT
cet-14807	54	8	8.55	8.55	NUM
cet-14807	54	9	kcal	kcal	NOUN
cet-14807	54	10	/	/	SYM
cet-14807	54	11	mol	mol	NOUN
cet-14807	54	12	that	that	PRON
cet-14807	54	13	inhibits	inhibit	VERB
cet-14807	54	14	some	some	DET
cet-14807	54	15	parts	part	NOUN
cet-14807	54	16	of	of	ADP
cet-14807	54	17	the	the	DET
cet-14807	54	18	catalytic	catalytic	ADJ
cet-14807	54	19	triad	triad	NOUN
cet-14807	54	20	through	through	ADP
cet-14807	54	21	hydrophobic	hydrophobic	NOUN
cet-14807	54	22	bonding	bonding	NOUN
cet-14807	54	23	with	with	ADP
cet-14807	54	24	his-51	his-51	PROPN
cet-14807	54	25	nad	nad	PROPN
cet-14807	54	26	asp-75	asp-75	PROPN
cet-14807	54	27	.	.	PUNCT
cet-14807	54	28	kaempferol-3	kaempferol-3	PROPN
cet-14807	54	29	-	-	PUNCT
cet-14807	54	30	oglucuronide	oglucuronide	NOUN
cet-14807	54	31	exhibits	exhibit	VERB
cet-14807	54	32	a	a	DET
cet-14807	54	33	binding	bind	VERB
cet-14807	54	34	affinity	affinity	NOUN
cet-14807	54	35	of	of	ADP
cet-14807	54	36	–	–	PUNCT
cet-14807	54	37	8.37	8.37	NUM
cet-14807	54	38	kcal	kcal	NOUN
cet-14807	54	39	/	/	SYM
cet-14807	54	40	mol	mol	ADP
cet-14807	54	41	that	that	PRON
cet-14807	54	42	also	also	ADV
cet-14807	54	43	inhibits	inhibit	VERB
cet-14807	54	44	some	some	DET
cet-14807	54	45	parts	part	NOUN
cet-14807	54	46	of	of	ADP
cet-14807	54	47	the	the	DET
cet-14807	54	48	catalytic	catalytic	ADJ
cet-14807	54	49	triad	triad	VERB
cet-14807	54	50	by	by	ADP
cet-14807	54	51	hydrogen	hydrogen	NOUN
cet-14807	54	52	bonding	bonding	NOUN
cet-14807	54	53	of	of	ADP
cet-14807	54	54	asp-75	asp-75	PROPN
cet-14807	54	55	and	and	CCONJ
cet-14807	54	56	his-51	his-51	NOUN
cet-14807	54	57	due	due	ADP
cet-14807	54	58	to	to	ADP
cet-14807	54	59	its	its	PRON
cet-14807	54	60	abundance	abundance	NOUN
cet-14807	54	61	of	of	ADP
cet-14807	54	62	oxygen	oxygen	NOUN
cet-14807	54	63	atoms	atom	NOUN
cet-14807	54	64	within	within	ADP
cet-14807	54	65	the	the	DET
cet-14807	54	66	bioactive	bioactive	PROPN
cet-14807	54	67	component	component	NOUN
cet-14807	54	68	.	.	PUNCT
cet-14807	55	1	hyperoside	hyperoside	PROPN
cet-14807	55	2	showed	show	VERB
cet-14807	55	3	a	a	DET
cet-14807	55	4	binding	bind	VERB
cet-14807	55	5	affinity	affinity	NOUN
cet-14807	55	6	of	of	ADP
cet-14807	55	7	–	–	PUNCT
cet-14807	55	8	8.19	8.19	NUM
cet-14807	55	9	kcal	kcal	NOUN
cet-14807	55	10	/	/	SYM
cet-14807	55	11	mol	mol	ADP
cet-14807	55	12	that	that	PRON
cet-14807	55	13	also	also	ADV
cet-14807	55	14	inhibits	inhibit	VERB
cet-14807	55	15	all	all	DET
cet-14807	55	16	three	three	NUM
cet-14807	55	17	of	of	ADP
cet-14807	55	18	the	the	DET
cet-14807	55	19	amino	amino	ADJ
cet-14807	55	20	acids	acid	NOUN
cet-14807	55	21	that	that	PRON
cet-14807	55	22	are	be	AUX
cet-14807	55	23	present	present	ADJ
cet-14807	55	24	in	in	ADP
cet-14807	55	25	the	the	DET
cet-14807	55	26	catalytic	catalytic	NOUN
cet-14807	55	27	triad	triad	NOUN
cet-14807	55	28	through	through	ADP
cet-14807	55	29	hydrogen	hydrogen	NOUN
cet-14807	55	30	bonding	bonding	NOUN
cet-14807	55	31	.	.	PUNCT
cet-14807	56	1	it	it	PRON
cet-14807	56	2	shows	show	VERB
cet-14807	56	3	that	that	SCONJ
cet-14807	56	4	high	high	ADJ
cet-14807	56	5	abundance	abundance	NOUN
cet-14807	56	6	of	of	ADP
cet-14807	56	7	oxygen	oxygen	NOUN
cet-14807	56	8	atoms	atom	NOUN
cet-14807	56	9	within	within	ADP
cet-14807	56	10	the	the	DET
cet-14807	56	11	bioactive	bioactive	ADJ
cet-14807	56	12	components	component	NOUN
cet-14807	56	13	result	result	VERB
cet-14807	56	14	in	in	ADP
cet-14807	56	15	higher	high	ADJ
cet-14807	56	16	binding	bind	VERB
cet-14807	56	17	affinities	affinity	NOUN
cet-14807	56	18	and	and	CCONJ
cet-14807	56	19	higher	high	ADJ
cet-14807	56	20	chance	chance	NOUN
cet-14807	56	21	of	of	ADP
cet-14807	56	22	inhibiting	inhibit	VERB
cet-14807	56	23	the	the	DET
cet-14807	56	24	catalytic	catalytic	ADJ
cet-14807	56	25	triad	triad	NOUN
cet-14807	56	26	whether	whether	SCONJ
cet-14807	56	27	through	through	ADP
cet-14807	56	28	hydrogen	hydrogen	NOUN
cet-14807	56	29	bonding	bonding	NOUN
cet-14807	56	30	or	or	CCONJ
cet-14807	56	31	hydrophobic	hydrophobic	NOUN
cet-14807	56	32	bonding	bonding	NOUN
cet-14807	56	33	.	.	PUNCT
cet-14807	57	1	table	table	NOUN
cet-14807	57	2	3	3	NUM
cet-14807	57	3	:	:	PUNCT
cet-14807	57	4	blood	blood	NOUN
cet-14807	57	5	-	-	PUNCT
cet-14807	57	6	brain	brain	NOUN
cet-14807	57	7	barrier	barrier	NOUN
cet-14807	57	8	,	,	PUNCT
cet-14807	57	9	toxicity	toxicity	NOUN
cet-14807	57	10	analysis	analysis	NOUN
cet-14807	57	11	and	and	CCONJ
cet-14807	57	12	lipinski	lipinski	PROPN
cet-14807	57	13	result	result	NOUN
cet-14807	57	14	of	of	ADP
cet-14807	57	15	the	the	DET
cet-14807	57	16	18	18	NUM
cet-14807	57	17	bioactive	bioactive	ADJ
cet-14807	57	18	components	component	NOUN
cet-14807	57	19	of	of	ADP
cet-14807	57	20	euphorbia	euphorbia	ADJ
cet-14807	57	21	hirta	hirta	PROPN
cet-14807	57	22	l.	l.	PROPN
cet-14807	57	23	compound	compound	PROPN
cet-14807	57	24	blood	blood	NOUN
cet-14807	57	25	-	-	PUNCT
cet-14807	57	26	brain	brain	NOUN
cet-14807	57	27	barrier	barrier	NOUN
cet-14807	57	28	(	(	PUNCT
cet-14807	57	29	bbb	bbb	NOUN
cet-14807	57	30	)	)	PUNCT
cet-14807	57	31	acute	acute	ADJ
cet-14807	57	32	oral	oral	ADJ
cet-14807	57	33	toxicity	toxicity	NOUN
cet-14807	57	34	carcinogenicity	carcinogenicity	NOUN
cet-14807	57	35	(	(	PUNCT
cet-14807	57	36	binary	binary	ADJ
cet-14807	57	37	)	)	PUNCT
cet-14807	57	38	hepatotoxicity	hepatotoxicity	PROPN
cet-14807	57	39	lipinski	lipinski	PROPN
cet-14807	57	40	result	result	PROPN
cet-14807	57	41	value	value	NOUN
cet-14807	57	42	probability	probability	NOUN
cet-14807	57	43	value	value	NOUN
cet-14807	57	44	probability	probability	NOUN
cet-14807	57	45	value	value	NOUN
cet-14807	57	46	probability	probability	NOUN
cet-14807	57	47	value	value	NOUN
cet-14807	57	48	probability	probability	NOUN
cet-14807	57	49	24hydroperoxycycloart25	24hydroperoxycycloart25	PROPN
cet-14807	57	50	-	-	PUNCT
cet-14807	57	51	en-3beta	en-3beta	PROPN
cet-14807	57	52	-	-	PUNCT
cet-14807	57	53	ol	ol	PROPN
cet-14807	57	54	+	+	NOUN
cet-14807	58	1	0.6500	0.6500	NUM
cet-14807	58	2	iii	iii	NUM
cet-14807	58	3	0.4576	0.4576	NUM
cet-14807	58	4	0.6306	0.6306	NUM
cet-14807	58	5	0.6968	0.6968	NUM
cet-14807	58	6	orally	orally	ADV
cet-14807	58	7	viable	viable	ADJ
cet-14807	58	8	2	2	NUM
cet-14807	58	9	-	-	PUNCT
cet-14807	58	10	coumaroylquinic	coumaroylquinic	ADJ
cet-14807	58	11	acid	acid	NOUN
cet-14807	58	12	0.5250	0.5250	NUM
cet-14807	58	13	iii	iii	NUM
cet-14807	58	14	0.7858	0.7858	NUM
cet-14807	58	15	0.9064	0.9064	NUM
cet-14807	58	16	+	+	CCONJ
cet-14807	58	17	0.6243	0.6243	NUM
cet-14807	58	18	orally	orally	ADV
cet-14807	58	19	viable	viable	ADJ
cet-14807	58	20	brevifolin	brevifolin	NOUN
cet-14807	58	21	carboxylic	carboxylic	ADJ
cet-14807	58	22	acid	acid	NOUN
cet-14807	58	23	0.6750	0.6750	NUM
cet-14807	58	24	iv	iv	NUM
cet-14807	58	25	0.4155	0.4155	NUM
cet-14807	58	26	1.0000	1.0000	NUM
cet-14807	58	27	+	+	CCONJ
cet-14807	58	28	0.6000	0.6000	NUM
cet-14807	58	29	orally	orally	ADV
cet-14807	58	30	viable	viable	ADJ
cet-14807	58	31	chelidonic	chelidonic	ADJ
cet-14807	58	32	acid	acid	NOUN
cet-14807	58	33	0.7500	0.7500	NUM
cet-14807	58	34	iii	iii	NUM
cet-14807	58	35	0.5236	0.5236	NUM
cet-14807	58	36	0.8434	0.8434	NUM
cet-14807	58	37	+	+	CCONJ
cet-14807	58	38	0.6750	0.6750	NUM
cet-14807	58	39	orally	orally	ADV
cet-14807	58	40	viable	viable	ADJ
cet-14807	58	41	corchoionoside	corchoionoside	NOUN
cet-14807	58	42	c	c	PROPN
cet-14807	58	43	0.5500	0.5500	NUM
cet-14807	58	44	iii	iii	NUM
cet-14807	58	45	0.7159	0.7159	NUM
cet-14807	58	46	0.9800	0.9800	NUM
cet-14807	58	47	0.8000	0.8000	NUM
cet-14807	58	48	orally	orally	ADV
cet-14807	58	49	viable	viable	ADJ
cet-14807	58	50	corilagin	corilagin	NOUN
cet-14807	58	51	0.7750	0.7750	NUM
cet-14807	58	52	iii	iii	X
cet-14807	58	53	0.4887	0.4887	NUM
cet-14807	58	54	0.9900	0.9900	NUM
cet-14807	58	55	0.6750	0.6750	NUM
cet-14807	58	56	not	not	PART
cet-14807	58	57	orally	orally	ADV
cet-14807	58	58	viable	viable	ADJ
cet-14807	58	59	cycloart-23	cycloart-23	NOUN
cet-14807	58	60	-	-	PUNCT
cet-14807	58	61	ene3beta,25	ene3beta,25	NOUN
cet-14807	58	62	-	-	PUNCT
cet-14807	58	63	diol	diol	NOUN
cet-14807	58	64	+	+	NUM
cet-14807	58	65	0.7000	0.7000	NUM
cet-14807	58	66	iii	iii	NUM
cet-14807	58	67	0.6549	0.6549	NUM
cet-14807	58	68	0.8400	0.8400	NUM
cet-14807	58	69	0.6125	0.6125	NUM
cet-14807	58	70	orally	orally	ADV
cet-14807	58	71	viable	viable	ADJ
cet-14807	58	72	ellagic	ellagic	ADJ
cet-14807	58	73	acid	acid	NOUN
cet-14807	58	74	0.8250	0.8250	NUM
cet-14807	58	75	ii	ii	PROPN
cet-14807	58	76	0.6020	0.6020	NUM
cet-14807	58	77	1.0000	1.0000	NUM
cet-14807	58	78	+	+	CCONJ
cet-14807	58	79	0.6948	0.6948	NUM
cet-14807	58	80	orally	orally	ADV
cet-14807	58	81	viable	viable	ADJ
cet-14807	58	82	epicatechin	epicatechin	NOUN
cet-14807	58	83	0.6750	0.6750	NUM
cet-14807	58	84	iv	iv	NUM
cet-14807	58	85	0.6433	0.6433	NUM
cet-14807	58	86	0.9700	0.9700	NUM
cet-14807	58	87	0.7375	0.7375	NUM
cet-14807	58	88	orally	orally	ADV
cet-14807	58	89	viable	viable	ADJ
cet-14807	58	90	feruloyl	feruloyl	ADJ
cet-14807	58	91	malate	malate	NOUN
cet-14807	58	92	0.6000	0.6000	NUM
cet-14807	58	93	iii	iii	NUM
cet-14807	58	94	0.6197	0.6197	NUM
cet-14807	58	95	0.8018	0.8018	NUM
cet-14807	58	96	0.7000	0.7000	NUM
cet-14807	58	97	orally	orally	ADV
cet-14807	58	98	viable	viable	ADJ
cet-14807	58	99	hyperoside	hyperoside	NOUN
cet-14807	58	100	0.7750	0.7750	NUM
cet-14807	58	101	iii	iii	NUM
cet-14807	58	102	0.4045	0.4045	NUM
cet-14807	58	103	1.0000	1.0000	NUM
cet-14807	58	104	0.5196	0.5196	NUM
cet-14807	58	105	not	not	PART
cet-14807	58	106	orally	orally	ADV
cet-14807	58	107	viable	viable	ADJ
cet-14807	58	108	isojaponin	isojaponin	NOUN
cet-14807	58	109	a	a	DET
cet-14807	58	110	0.7000	0.7000	NUM
cet-14807	58	111	i	i	NOUN
cet-14807	58	112	0.4630	0.4630	NUM
cet-14807	58	113	0.9800	0.9800	NUM
cet-14807	58	114	+	+	CCONJ
cet-14807	58	115	0.5825	0.5825	NUM
cet-14807	58	116	orally	orally	ADV
cet-14807	58	117	viable	viable	ADJ
cet-14807	58	118	kaempferol-3	kaempferol-3	NOUN
cet-14807	58	119	-	-	PUNCT
cet-14807	58	120	oglucuronide	oglucuronide	NOUN
cet-14807	58	121	0.8250	0.8250	NUM
cet-14807	58	122	ii	ii	NOUN
cet-14807	58	123	0.4816	0.4816	NUM
cet-14807	58	124	1.0000	1.0000	NUM
cet-14807	58	125	0.6782	0.6782	NUM
cet-14807	58	126	not	not	PART
cet-14807	58	127	orally	orally	ADV
cet-14807	58	128	viable	viable	ADJ
cet-14807	58	129	luteolin-7	luteolin-7	NOUN
cet-14807	58	130	-	-	PUNCT
cet-14807	58	131	o	o	NOUN
cet-14807	58	132	-	-	ADJ
cet-14807	58	133	beta	beta	NOUN
cet-14807	58	134	-	-	PUNCT
cet-14807	58	135	dglucopyranoside	dglucopyranoside	NOUN
cet-14807	58	136	0.7500	0.7500	NUM
cet-14807	58	137	iv	iv	NUM
cet-14807	58	138	0.4763	0.4763	NUM
cet-14807	58	139	0.9900	0.9900	NUM
cet-14807	58	140	0.8821	0.8821	NUM
cet-14807	58	141	not	not	PART
cet-14807	58	142	orally	orally	ADV
cet-14807	58	143	viable	viable	ADJ
cet-14807	58	144	syringin	syringin	NOUN
cet-14807	58	145	0.5250	0.5250	NUM
cet-14807	58	146	iii	iii	NUM
cet-14807	58	147	0.7551	0.7551	NUM
cet-14807	58	148	0.6989	0.6989	NUM
cet-14807	58	149	0.7822	0.7822	NUM
cet-14807	58	150	orally	orally	ADV
cet-14807	58	151	viable	viable	ADJ
cet-14807	58	152	trigallic	trigallic	ADJ
cet-14807	58	153	acid	acid	NOUN
cet-14807	58	154	0.7000	0.7000	NUM
cet-14807	58	155	iii	iii	NUM
cet-14807	58	156	0.8285	0.8285	NUM
cet-14807	58	157	0.7997	0.7997	NUM
cet-14807	58	158	+	+	CCONJ
cet-14807	58	159	0.7125	0.7125	NUM
cet-14807	58	160	not	not	PART
cet-14807	58	161	orally	orally	ADV
cet-14807	58	162	viable	viable	ADJ
cet-14807	58	163	tryptophan	tryptophan	NOUN
cet-14807	58	164	+	+	CCONJ
cet-14807	58	165	0.8500	0.8500	NUM
cet-14807	58	166	iv	iv	NUM
cet-14807	58	167	0.6272	0.6272	NUM
cet-14807	58	168	0.7800	0.7800	NUM
cet-14807	58	169	+	+	CCONJ
cet-14807	58	170	0.5166	0.5166	NUM
cet-14807	58	171	orally	orally	ADV
cet-14807	58	172	viable	viable	ADJ
cet-14807	58	173	tyrosylglutamate	tyrosylglutamate	NOUN
cet-14807	58	174	0.5500	0.5500	NUM
cet-14807	58	175	iii	iii	NUM
cet-14807	58	176	0.6636	0.6636	NUM
cet-14807	58	177	0.8122	0.8122	NUM
cet-14807	58	178	0.6146	0.6146	NUM
cet-14807	58	179	orally	orally	ADV
cet-14807	58	180	viable	viable	ADJ
cet-14807	58	181	70	70	NUM
cet-14807	58	182	the	the	DET
cet-14807	58	183	blood	blood	NOUN
cet-14807	58	184	-	-	PUNCT
cet-14807	58	185	brain	brain	NOUN
cet-14807	58	186	barrier	barrier	NOUN
cet-14807	58	187	(	(	PUNCT
cet-14807	58	188	bbb	bbb	NOUN
cet-14807	58	189	)	)	PUNCT
cet-14807	58	190	is	be	AUX
cet-14807	58	191	crucial	crucial	ADJ
cet-14807	58	192	in	in	ADP
cet-14807	58	193	preventing	prevent	VERB
cet-14807	58	194	neuroinvasion	neuroinvasion	NOUN
cet-14807	58	195	by	by	ADP
cet-14807	58	196	viruses	virus	NOUN
cet-14807	58	197	,	,	PUNCT
cet-14807	58	198	including	include	VERB
cet-14807	58	199	the	the	DET
cet-14807	58	200	four	four	NUM
cet-14807	58	201	denv	denv	NOUN
cet-14807	58	202	serotypes	serotype	NOUN
cet-14807	58	203	,	,	PUNCT
cet-14807	58	204	which	which	PRON
cet-14807	58	205	can	can	AUX
cet-14807	58	206	cause	cause	VERB
cet-14807	58	207	neurological	neurological	ADJ
cet-14807	58	208	issues	issue	NOUN
cet-14807	58	209	by	by	ADP
cet-14807	58	210	entering	enter	VERB
cet-14807	58	211	the	the	DET
cet-14807	58	212	central	central	ADJ
cet-14807	58	213	nervous	nervous	ADJ
cet-14807	58	214	system	system	NOUN
cet-14807	58	215	via	via	ADP
cet-14807	58	216	the	the	DET
cet-14807	58	217	bloodstream	bloodstream	NOUN
cet-14807	58	218	.	.	PUNCT
cet-14807	59	1	denv-2	denv-2	PROPN
cet-14807	60	1	and	and	CCONJ
cet-14807	60	2	denv-3	denv-3	PRON
cet-14807	60	3	are	be	AUX
cet-14807	60	4	most	most	ADV
cet-14807	60	5	associated	associate	VERB
cet-14807	60	6	with	with	ADP
cet-14807	60	7	bbb	bbb	PROPN
cet-14807	60	8	infection	infection	NOUN
cet-14807	60	9	(	(	PUNCT
cet-14807	60	10	calderon	calderon	NOUN
cet-14807	60	11	-	-	PUNCT
cet-14807	60	12	pelaez	pelaez	PROPN
cet-14807	60	13	et	et	PROPN
cet-14807	60	14	al	al	PROPN
cet-14807	60	15	.	.	PROPN
cet-14807	60	16	,	,	PUNCT
cet-14807	60	17	2019	2019	NUM
cet-14807	60	18	)	)	PUNCT
cet-14807	60	19	.	.	PUNCT
cet-14807	61	1	neurological	neurological	ADJ
cet-14807	61	2	effects	effect	NOUN
cet-14807	61	3	are	be	AUX
cet-14807	61	4	seen	see	VERB
cet-14807	61	5	in	in	ADP
cet-14807	61	6	all	all	DET
cet-14807	61	7	age	age	NOUN
cet-14807	61	8	groups	group	NOUN
cet-14807	61	9	in	in	ADP
cet-14807	61	10	dengue	dengue	NOUN
cet-14807	61	11	-	-	PUNCT
cet-14807	61	12	endemic	endemic	ADJ
cet-14807	61	13	areas	area	NOUN
cet-14807	61	14	(	(	PUNCT
cet-14807	61	15	hapuarachchi	hapuarachchi	PROPN
cet-14807	61	16	et	et	PROPN
cet-14807	61	17	al	al	PROPN
cet-14807	61	18	.	.	PROPN
cet-14807	61	19	,	,	PUNCT
cet-14807	61	20	2015	2015	NUM
cet-14807	61	21	)	)	PUNCT
cet-14807	61	22	.	.	PUNCT
cet-14807	62	1	microvascular	microvascular	ADJ
cet-14807	62	2	endothelial	endothelial	ADJ
cet-14807	62	3	cells	cell	NOUN
cet-14807	62	4	protect	protect	VERB
cet-14807	62	5	the	the	DET
cet-14807	62	6	cns	cns	NOUN
cet-14807	62	7	from	from	ADP
cet-14807	62	8	toxins	toxin	NOUN
cet-14807	62	9	,	,	PUNCT
cet-14807	62	10	provide	provide	VERB
cet-14807	62	11	nutrients	nutrient	NOUN
cet-14807	62	12	,	,	PUNCT
cet-14807	62	13	and	and	CCONJ
cet-14807	62	14	filter	filter	VERB
cet-14807	62	15	harmful	harmful	ADJ
cet-14807	62	16	compounds	compound	NOUN
cet-14807	62	17	(	(	PUNCT
cet-14807	62	18	persidsky	persidsky	NOUN
cet-14807	62	19	et	et	PROPN
cet-14807	62	20	al	al	PROPN
cet-14807	62	21	.	.	PROPN
cet-14807	62	22	,	,	PUNCT
cet-14807	62	23	2006	2006	NUM
cet-14807	62	24	)	)	PUNCT
cet-14807	62	25	.	.	PUNCT
cet-14807	63	1	in	in	ADP
cet-14807	63	2	table	table	NOUN
cet-14807	63	3	3	3	NUM
cet-14807	63	4	predicts	predict	VERB
cet-14807	63	5	the	the	DET
cet-14807	63	6	bbb	bbb	NOUN
cet-14807	63	7	penetration	penetration	NOUN
cet-14807	63	8	of	of	ADP
cet-14807	63	9	compounds	compound	NOUN
cet-14807	63	10	:	:	PUNCT
cet-14807	63	11	bioactive	bioactive	NOUN
cet-14807	63	12	components	component	NOUN
cet-14807	63	13	with	with	ADP
cet-14807	63	14	a	a	DET
cet-14807	63	15	(	(	PUNCT
cet-14807	63	16	+	+	NOUN
cet-14807	63	17	)	)	PUNCT
cet-14807	63	18	value	value	NOUN
cet-14807	63	19	are	be	AUX
cet-14807	63	20	likely	likely	ADJ
cet-14807	63	21	to	to	PART
cet-14807	63	22	cross	cross	VERB
cet-14807	63	23	the	the	DET
cet-14807	63	24	bbb	bbb	NOUN
cet-14807	63	25	,	,	PUNCT
cet-14807	63	26	while	while	SCONJ
cet-14807	63	27	those	those	PRON
cet-14807	63	28	with	with	ADP
cet-14807	63	29	a	a	DET
cet-14807	63	30	(	(	PUNCT
cet-14807	63	31	-	-	PUNCT
cet-14807	63	32	)	)	PUNCT
cet-14807	63	33	value	value	NOUN
cet-14807	63	34	are	be	AUX
cet-14807	63	35	not	not	PART
cet-14807	63	36	.	.	PUNCT
cet-14807	64	1	out	out	ADP
cet-14807	64	2	of	of	ADP
cet-14807	64	3	18	18	NUM
cet-14807	64	4	bioactive	bioactive	ADJ
cet-14807	64	5	components	component	NOUN
cet-14807	64	6	,	,	PUNCT
cet-14807	64	7	three	three	NUM
cet-14807	64	8	are	be	AUX
cet-14807	64	9	predicted	predict	VERB
cet-14807	64	10	to	to	PART
cet-14807	64	11	penetrate	penetrate	VERB
cet-14807	64	12	the	the	DET
cet-14807	64	13	bbb	bbb	NOUN
cet-14807	64	14	:	:	PUNCT
cet-14807	64	15	24	24	NUM
cet-14807	64	16	-	-	PUNCT
cet-14807	64	17	hydroperoxycycloart-25	hydroperoxycycloart-25	PROPN
cet-14807	64	18	-	-	PUNCT
cet-14807	64	19	en-3beta	en-3beta	PROPN
cet-14807	64	20	-	-	PUNCT
cet-14807	64	21	ol	ol	PROPN
cet-14807	64	22	,	,	PUNCT
cet-14807	64	23	cycloart-23	cycloart-23	NOUN
cet-14807	64	24	-	-	PUNCT
cet-14807	64	25	ene-3beta,25	ene-3beta,25	CCONJ
cet-14807	64	26	-	-	PUNCT
cet-14807	64	27	diol	diol	NOUN
cet-14807	64	28	,	,	PUNCT
cet-14807	64	29	and	and	CCONJ
cet-14807	64	30	tryptophan	tryptophan	NOUN
cet-14807	64	31	.	.	PUNCT
cet-14807	65	1	the	the	DET
cet-14807	65	2	toxicity	toxicity	NOUN
cet-14807	65	3	analysis	analysis	NOUN
cet-14807	65	4	evaluates	evaluate	VERB
cet-14807	65	5	the	the	DET
cet-14807	65	6	predicted	predict	VERB
cet-14807	65	7	toxicity	toxicity	NOUN
cet-14807	65	8	of	of	ADP
cet-14807	65	9	euphorbia	euphorbia	ADJ
cet-14807	65	10	hirta	hirta	PROPN
cet-14807	65	11	l.	l.	PROPN
cet-14807	65	12	bioactive	bioactive	PROPN
cet-14807	65	13	components	component	NOUN
cet-14807	65	14	.	.	PUNCT
cet-14807	66	1	acute	acute	ADJ
cet-14807	66	2	oral	oral	ADJ
cet-14807	66	3	toxicity	toxicity	NOUN
cet-14807	66	4	is	be	AUX
cet-14807	66	5	classified	classify	VERB
cet-14807	66	6	into	into	ADP
cet-14807	66	7	four	four	NUM
cet-14807	66	8	categories	category	NOUN
cet-14807	66	9	based	base	VERB
cet-14807	66	10	on	on	ADP
cet-14807	66	11	ld50	ld50	PROPN
cet-14807	66	12	values	value	NOUN
cet-14807	66	13	:	:	PUNCT
cet-14807	66	14	i	i	PRON
cet-14807	66	15	(	(	PUNCT
cet-14807	66	16	danger	danger	NOUN
cet-14807	66	17	,	,	PUNCT
cet-14807	66	18	ld50	ld50	PROPN
cet-14807	66	19	less	less	ADJ
cet-14807	66	20	than	than	ADP
cet-14807	66	21	or	or	CCONJ
cet-14807	66	22	equal	equal	ADJ
cet-14807	66	23	to	to	ADP
cet-14807	66	24	50	50	NUM
cet-14807	66	25	mg	mg	PROPN
cet-14807	66	26	/	/	SYM
cet-14807	66	27	kg	kg	PROPN
cet-14807	66	28	)	)	PUNCT
cet-14807	66	29	,	,	PUNCT
cet-14807	66	30	ii	ii	PROPN
cet-14807	66	31	(	(	PUNCT
cet-14807	66	32	warning	warning	NOUN
cet-14807	66	33	,	,	PUNCT
cet-14807	66	34	ld50	ld50	PROPN
cet-14807	66	35	greater	great	ADJ
cet-14807	66	36	than	than	ADP
cet-14807	66	37	50	50	NUM
cet-14807	66	38	mg	mg	NUM
cet-14807	66	39	/	/	SYM
cet-14807	66	40	kg	kg	PROPN
cet-14807	66	41	and	and	CCONJ
cet-14807	66	42	less	less	ADJ
cet-14807	66	43	than	than	ADP
cet-14807	66	44	or	or	CCONJ
cet-14807	66	45	equal	equal	ADJ
cet-14807	66	46	to	to	ADP
cet-14807	66	47	500	500	NUM
cet-14807	66	48	mg	mg	PROPN
cet-14807	66	49	/	/	SYM
cet-14807	66	50	kg	kg	PROPN
cet-14807	66	51	)	)	PUNCT
cet-14807	66	52	,	,	PUNCT
cet-14807	66	53	iii	iii	X
cet-14807	66	54	(	(	PUNCT
cet-14807	66	55	caution	caution	NOUN
cet-14807	66	56	,	,	PUNCT
cet-14807	66	57	ld50	ld50	PROPN
cet-14807	66	58	greater	great	ADJ
cet-14807	66	59	than	than	ADP
cet-14807	66	60	500	500	NUM
cet-14807	66	61	mg	mg	NUM
cet-14807	66	62	/	/	SYM
cet-14807	66	63	kg	kg	PROPN
cet-14807	66	64	and	and	CCONJ
cet-14807	66	65	less	less	ADJ
cet-14807	66	66	than	than	ADP
cet-14807	66	67	or	or	CCONJ
cet-14807	66	68	equal	equal	ADJ
cet-14807	66	69	to	to	ADP
cet-14807	66	70	5,000	5,000	NUM
cet-14807	66	71	mg	mg	PROPN
cet-14807	66	72	/	/	SYM
cet-14807	66	73	kg	kg	PROPN
cet-14807	66	74	)	)	PUNCT
cet-14807	66	75	,	,	PUNCT
cet-14807	66	76	and	and	CCONJ
cet-14807	66	77	iv	iv	X
cet-14807	66	78	(	(	PUNCT
cet-14807	66	79	non	non	ADJ
cet-14807	66	80	-	-	ADJ
cet-14807	66	81	required	required	ADJ
cet-14807	66	82	,	,	PUNCT
cet-14807	66	83	ld50	ld50	PROPN
cet-14807	66	84	greater	great	ADJ
cet-14807	66	85	than	than	ADP
cet-14807	66	86	or	or	CCONJ
cet-14807	66	87	equal	equal	ADJ
cet-14807	66	88	to	to	ADP
cet-14807	66	89	5,000	5,000	NUM
cet-14807	66	90	mg	mg	PROPN
cet-14807	66	91	/	/	SYM
cet-14807	66	92	kg	kg	NOUN
cet-14807	66	93	)	)	PUNCT
cet-14807	66	94	(	(	PUNCT
cet-14807	66	95	lipinski	lipinski	PROPN
cet-14807	66	96	,	,	PUNCT
cet-14807	66	97	2001	2001	NUM
cet-14807	66	98	)	)	PUNCT
cet-14807	66	99	.	.	PUNCT
cet-14807	67	1	most	most	ADJ
cet-14807	67	2	components	component	NOUN
cet-14807	67	3	fall	fall	VERB
cet-14807	67	4	into	into	ADP
cet-14807	67	5	categories	category	NOUN
cet-14807	67	6	iii	iii	PROPN
cet-14807	67	7	and	and	CCONJ
cet-14807	67	8	iv	iv	NUM
cet-14807	67	9	,	,	PUNCT
cet-14807	67	10	with	with	ADP
cet-14807	67	11	only	only	ADJ
cet-14807	67	12	isojaponin	isojaponin	NOUN
cet-14807	67	13	a	a	DET
cet-14807	67	14	in	in	ADP
cet-14807	67	15	category	category	NOUN
cet-14807	67	16	i	i	NOUN
cet-14807	67	17	,	,	PUNCT
cet-14807	67	18	and	and	CCONJ
cet-14807	67	19	ellagic	ellagic	ADJ
cet-14807	67	20	acid	acid	NOUN
cet-14807	67	21	and	and	CCONJ
cet-14807	67	22	kaempferol-3	kaempferol-3	PROPN
cet-14807	67	23	-	-	PUNCT
cet-14807	67	24	o	o	NOUN
cet-14807	67	25	-	-	ADJ
cet-14807	67	26	glucuronide	glucuronide	ADJ
cet-14807	67	27	in	in	ADP
cet-14807	67	28	category	category	PROPN
cet-14807	67	29	ii	ii	PROPN
cet-14807	67	30	.	.	PUNCT
cet-14807	68	1	carcinogenicity	carcinogenicity	NOUN
cet-14807	68	2	is	be	AUX
cet-14807	68	3	assessed	assess	VERB
cet-14807	68	4	using	use	VERB
cet-14807	68	5	binary	binary	ADJ
cet-14807	68	6	model	model	NOUN
cet-14807	68	7	.	.	PUNCT
cet-14807	69	1	the	the	DET
cet-14807	69	2	binary	binary	PROPN
cet-14807	69	3	model	model	NOUN
cet-14807	69	4	predicts	predict	VERB
cet-14807	69	5	whether	whether	SCONJ
cet-14807	69	6	compounds	compound	NOUN
cet-14807	69	7	are	be	AUX
cet-14807	69	8	carcinogenic	carcinogenic	ADJ
cet-14807	69	9	(	(	PUNCT
cet-14807	69	10	+	+	ADJ
cet-14807	69	11	)	)	PUNCT
cet-14807	69	12	or	or	CCONJ
cet-14807	69	13	not	not	PART
cet-14807	69	14	(	(	PUNCT
cet-14807	69	15	-	-	PUNCT
cet-14807	69	16	)	)	PUNCT
cet-14807	69	17	(	(	PUNCT
cet-14807	69	18	syahputra	syahputra	PROPN
cet-14807	69	19	et	et	PROPN
cet-14807	69	20	al	al	PROPN
cet-14807	69	21	.	.	PROPN
cet-14807	69	22	,	,	PUNCT
cet-14807	69	23	2021	2021	NUM
cet-14807	69	24	)	)	PUNCT
cet-14807	69	25	.	.	PUNCT
cet-14807	70	1	all	all	DET
cet-14807	70	2	euphorbia	euphorbia	PROPN
cet-14807	70	3	hirta	hirta	PROPN
cet-14807	70	4	l.	l.	PROPN
cet-14807	70	5	bioactive	bioactive	PROPN
cet-14807	70	6	components	component	NOUN
cet-14807	70	7	are	be	AUX
cet-14807	70	8	non	non	ADJ
cet-14807	70	9	-	-	ADJ
cet-14807	70	10	carcinogenic	carcinogenic	ADJ
cet-14807	70	11	.	.	PUNCT
cet-14807	71	1	hepatotoxicity	hepatotoxicity	NOUN
cet-14807	71	2	is	be	AUX
cet-14807	71	3	the	the	DET
cet-14807	71	4	ability	ability	NOUN
cet-14807	71	5	of	of	ADP
cet-14807	71	6	the	the	DET
cet-14807	71	7	compound	compound	NOUN
cet-14807	71	8	to	to	PART
cet-14807	71	9	damage	damage	VERB
cet-14807	71	10	the	the	DET
cet-14807	71	11	liver	liver	NOUN
cet-14807	71	12	.	.	PUNCT
cet-14807	72	1	compounds	compound	VERB
cet-14807	72	2	with	with	ADP
cet-14807	72	3	a	a	DET
cet-14807	72	4	(	(	PUNCT
cet-14807	72	5	+	+	NOUN
cet-14807	72	6	)	)	PUNCT
cet-14807	72	7	value	value	NOUN
cet-14807	72	8	are	be	AUX
cet-14807	72	9	hepatotoxic	hepatotoxic	ADJ
cet-14807	72	10	,	,	PUNCT
cet-14807	72	11	while	while	SCONJ
cet-14807	72	12	those	those	PRON
cet-14807	72	13	with	with	ADP
cet-14807	72	14	a	a	DET
cet-14807	72	15	(	(	PUNCT
cet-14807	72	16	-	-	PUNCT
cet-14807	72	17	)	)	PUNCT
cet-14807	72	18	value	value	NOUN
cet-14807	72	19	are	be	AUX
cet-14807	72	20	not	not	PART
cet-14807	72	21	(	(	PUNCT
cet-14807	72	22	syahputra	syahputra	PROPN
cet-14807	72	23	et	et	PROPN
cet-14807	72	24	al	al	PROPN
cet-14807	72	25	.	.	PROPN
cet-14807	72	26	,	,	PUNCT
cet-14807	72	27	2021	2021	NUM
cet-14807	72	28	)	)	PUNCT
cet-14807	72	29	.	.	PUNCT
cet-14807	73	1	seven	seven	NUM
cet-14807	73	2	bioactive	bioactive	ADJ
cet-14807	73	3	compounds	compound	NOUN
cet-14807	73	4	are	be	AUX
cet-14807	73	5	predicted	predict	VERB
cet-14807	73	6	to	to	PART
cet-14807	73	7	have	have	VERB
cet-14807	73	8	hepatotoxicity	hepatotoxicity	NOUN
cet-14807	73	9	:	:	PUNCT
cet-14807	73	10	brevifolin	brevifolin	NOUN
cet-14807	73	11	carboxylic	carboxylic	ADJ
cet-14807	73	12	acid	acid	NOUN
cet-14807	73	13	,	,	PUNCT
cet-14807	73	14	chelidonic	chelidonic	ADJ
cet-14807	73	15	acid	acid	NOUN
cet-14807	73	16	,	,	PUNCT
cet-14807	73	17	ellagic	ellagic	ADJ
cet-14807	73	18	acid	acid	NOUN
cet-14807	73	19	,	,	PUNCT
cet-14807	73	20	isojaponin	isojaponin	NOUN
cet-14807	73	21	a	a	PRON
cet-14807	73	22	,	,	PUNCT
cet-14807	73	23	tryptophan	tryptophan	NOUN
cet-14807	73	24	,	,	PUNCT
cet-14807	73	25	2	2	NUM
cet-14807	73	26	-	-	PUNCT
cet-14807	73	27	coumaroylquinic	coumaroylquinic	ADJ
cet-14807	73	28	acid	acid	NOUN
cet-14807	73	29	,	,	PUNCT
cet-14807	73	30	and	and	CCONJ
cet-14807	73	31	trigallic	trigallic	ADJ
cet-14807	73	32	acid	acid	NOUN
cet-14807	73	33	.	.	PUNCT
cet-14807	74	1	the	the	DET
cet-14807	74	2	others	other	NOUN
cet-14807	74	3	are	be	AUX
cet-14807	74	4	predicted	predict	VERB
cet-14807	74	5	to	to	PART
cet-14807	74	6	be	be	AUX
cet-14807	74	7	non	non	ADJ
cet-14807	74	8	-	-	ADJ
cet-14807	74	9	hepatotoxic	hepatotoxic	ADJ
cet-14807	74	10	.	.	PUNCT
cet-14807	75	1	the	the	DET
cet-14807	75	2	substantial	substantial	ADJ
cet-14807	75	3	presence	presence	NOUN
cet-14807	75	4	of	of	ADP
cet-14807	75	5	toxic	toxic	ADJ
cet-14807	75	6	components	component	NOUN
cet-14807	75	7	in	in	ADP
cet-14807	75	8	medicinal	medicinal	ADJ
cet-14807	75	9	plants	plant	NOUN
cet-14807	75	10	like	like	ADP
cet-14807	75	11	tawa	tawa	NOUN
cet-14807	75	12	-	-	PUNCT
cet-14807	75	13	tawa	tawa	NOUN
cet-14807	75	14	,	,	PUNCT
cet-14807	75	15	as	as	SCONJ
cet-14807	75	16	indicated	indicate	VERB
cet-14807	75	17	by	by	ADP
cet-14807	75	18	admetox	admetox	ADJ
cet-14807	75	19	results	result	NOUN
cet-14807	75	20	,	,	PUNCT
cet-14807	75	21	suggests	suggest	VERB
cet-14807	75	22	that	that	SCONJ
cet-14807	75	23	it	it	PRON
cet-14807	75	24	is	be	AUX
cet-14807	75	25	not	not	PART
cet-14807	75	26	advisable	advisable	ADJ
cet-14807	75	27	to	to	PART
cet-14807	75	28	simply	simply	ADV
cet-14807	75	29	boil	boil	VERB
cet-14807	75	30	the	the	DET
cet-14807	75	31	plant	plant	NOUN
cet-14807	75	32	in	in	ADP
cet-14807	75	33	water	water	NOUN
cet-14807	75	34	and	and	CCONJ
cet-14807	75	35	consume	consume	VERB
cet-14807	75	36	the	the	DET
cet-14807	75	37	solution	solution	NOUN
cet-14807	75	38	orally	orally	ADV
cet-14807	75	39	(	(	PUNCT
cet-14807	75	40	farzaei	farzaei	NOUN
cet-14807	75	41	,	,	PUNCT
cet-14807	75	42	2020	2020	NUM
cet-14807	75	43	)	)	PUNCT
cet-14807	75	44	.	.	PUNCT
cet-14807	76	1	pharmacokinetic	pharmacokinetic	ADJ
cet-14807	76	2	solubility	solubility	NOUN
cet-14807	76	3	and	and	CCONJ
cet-14807	76	4	permeability	permeability	NOUN
cet-14807	76	5	predictions	prediction	NOUN
cet-14807	76	6	were	be	AUX
cet-14807	76	7	performed	perform	VERB
cet-14807	76	8	using	use	VERB
cet-14807	76	9	swissadme	swissadme	NOUN
cet-14807	76	10	’s	’s	PART
cet-14807	76	11	lipinski	lipinski	PROPN
cet-14807	76	12	parameters	parameter	NOUN
cet-14807	76	13	,	,	PUNCT
cet-14807	76	14	shown	show	VERB
cet-14807	76	15	in	in	ADP
cet-14807	76	16	table	table	NOUN
cet-14807	76	17	3	3	NUM
cet-14807	76	18	.	.	PUNCT
cet-14807	77	1	the	the	DET
cet-14807	77	2	lipinski	lipinski	PROPN
cet-14807	77	3	rule	rule	NOUN
cet-14807	77	4	determines	determine	VERB
cet-14807	77	5	the	the	DET
cet-14807	77	6	drug	drug	NOUN
cet-14807	77	7	-	-	PUNCT
cet-14807	77	8	likeness	likeness	NOUN
cet-14807	77	9	of	of	ADP
cet-14807	77	10	compounds	compound	NOUN
cet-14807	77	11	for	for	ADP
cet-14807	77	12	absorption	absorption	NOUN
cet-14807	77	13	based	base	VERB
cet-14807	77	14	on	on	ADP
cet-14807	77	15	four	four	NUM
cet-14807	77	16	guidelines	guideline	NOUN
cet-14807	77	17	:	:	PUNCT
cet-14807	77	18	1	1	X
cet-14807	77	19	)	)	PUNCT
cet-14807	77	20	molecular	molecular	ADJ
cet-14807	77	21	weight	weight	NOUN
cet-14807	77	22	must	must	AUX
cet-14807	77	23	be	be	AUX
cet-14807	77	24	less	less	ADJ
cet-14807	77	25	than	than	ADP
cet-14807	77	26	or	or	CCONJ
cet-14807	77	27	equal	equal	ADJ
cet-14807	77	28	to	to	ADP
cet-14807	77	29	500	500	NUM
cet-14807	77	30	g	g	NOUN
cet-14807	77	31	/	/	SYM
cet-14807	77	32	mol	mol	NOUN
cet-14807	77	33	,	,	PUNCT
cet-14807	77	34	2	2	NUM
cet-14807	77	35	)	)	PUNCT
cet-14807	77	36	hydrogen	hydrogen	NOUN
cet-14807	77	37	bond	bond	NOUN
cet-14807	77	38	acceptors	acceptor	NOUN
cet-14807	77	39	must	must	AUX
cet-14807	77	40	be	be	AUX
cet-14807	77	41	less	less	ADJ
cet-14807	77	42	than	than	ADP
cet-14807	77	43	or	or	CCONJ
cet-14807	77	44	equal	equal	ADJ
cet-14807	77	45	to	to	ADP
cet-14807	77	46	10	10	NUM
cet-14807	77	47	,	,	PUNCT
cet-14807	77	48	3	3	X
cet-14807	77	49	)	)	PUNCT
cet-14807	77	50	hydrogen	hydrogen	NOUN
cet-14807	77	51	bond	bond	NOUN
cet-14807	77	52	donors	donor	NOUN
cet-14807	77	53	must	must	AUX
cet-14807	77	54	be	be	AUX
cet-14807	77	55	less	less	ADJ
cet-14807	77	56	than	than	ADP
cet-14807	77	57	or	or	CCONJ
cet-14807	77	58	equal	equal	ADJ
cet-14807	77	59	to	to	ADP
cet-14807	77	60	5	5	NUM
cet-14807	77	61	,	,	PUNCT
cet-14807	77	62	and	and	CCONJ
cet-14807	77	63	4	4	X
cet-14807	77	64	)	)	PUNCT
cet-14807	77	65	mlogp	mlogp	NOUN
cet-14807	77	66	be	be	AUX
cet-14807	77	67	less	less	ADJ
cet-14807	77	68	than	than	ADP
cet-14807	77	69	or	or	CCONJ
cet-14807	77	70	equal	equal	ADJ
cet-14807	77	71	to	to	ADP
cet-14807	77	72	4.15	4.15	NUM
cet-14807	77	73	.	.	PUNCT
cet-14807	78	1	compounds	compound	NOUN
cet-14807	78	2	should	should	AUX
cet-14807	78	3	not	not	PART
cet-14807	78	4	violate	violate	VERB
cet-14807	78	5	more	more	ADJ
cet-14807	78	6	than	than	ADP
cet-14807	78	7	one	one	NUM
cet-14807	78	8	guideline	guideline	NOUN
cet-14807	78	9	to	to	PART
cet-14807	78	10	ensure	ensure	VERB
cet-14807	78	11	good	good	ADJ
cet-14807	78	12	absorption	absorption	NOUN
cet-14807	78	13	and	and	CCONJ
cet-14807	78	14	permeability	permeability	NOUN
cet-14807	78	15	(	(	PUNCT
cet-14807	78	16	lipinski	lipinski	PROPN
cet-14807	78	17	et	et	PROPN
cet-14807	78	18	al	al	PROPN
cet-14807	78	19	.	.	PROPN
cet-14807	78	20	,	,	PUNCT
cet-14807	78	21	2001	2001	NUM
cet-14807	78	22	)	)	PUNCT
cet-14807	78	23	.	.	PUNCT
cet-14807	79	1	compounds	compound	NOUN
cet-14807	79	2	with	with	ADP
cet-14807	79	3	molecular	molecular	ADJ
cet-14807	79	4	weight	weight	NOUN
cet-14807	79	5	>	>	X
cet-14807	79	6	500	500	NUM
cet-14807	79	7	g	g	NOUN
cet-14807	79	8	/	/	SYM
cet-14807	79	9	mol	mol	X
cet-14807	79	10	diffuse	diffuse	NOUN
cet-14807	79	11	slowly	slowly	ADV
cet-14807	79	12	across	across	ADP
cet-14807	79	13	lipid	lipid	NOUN
cet-14807	79	14	membranes	membrane	NOUN
cet-14807	79	15	,	,	PUNCT
cet-14807	79	16	hindering	hinder	VERB
cet-14807	79	17	absorption	absorption	NOUN
cet-14807	79	18	.	.	PUNCT
cet-14807	80	1	hydrogen	hydrogen	NOUN
cet-14807	80	2	bond	bond	NOUN
cet-14807	80	3	donors	donor	NOUN
cet-14807	80	4	must	must	AUX
cet-14807	80	5	be	be	AUX
cet-14807	80	6	≤	≤	NUM
cet-14807	80	7	5	5	NUM
cet-14807	80	8	and	and	CCONJ
cet-14807	80	9	acceptors	acceptor	NOUN
cet-14807	80	10	≤	≤	NUM
cet-14807	80	11	10	10	NUM
cet-14807	80	12	to	to	PART
cet-14807	80	13	permeate	permeate	VERB
cet-14807	80	14	through	through	ADP
cet-14807	80	15	the	the	DET
cet-14807	80	16	lipid	lipid	NOUN
cet-14807	80	17	membrane	membrane	NOUN
cet-14807	80	18	,	,	PUNCT
cet-14807	80	19	as	as	SCONJ
cet-14807	80	20	they	they	PRON
cet-14807	80	21	interact	interact	VERB
cet-14807	80	22	with	with	ADP
cet-14807	80	23	water	water	NOUN
cet-14807	80	24	due	due	ADP
cet-14807	80	25	to	to	ADP
cet-14807	80	26	their	their	PRON
cet-14807	80	27	aquaphilic	aquaphilic	ADJ
cet-14807	80	28	nature	nature	NOUN
cet-14807	80	29	.	.	PUNCT
cet-14807	81	1	mlogp	mlogp	PROPN
cet-14807	81	2	,	,	PUNCT
cet-14807	81	3	the	the	DET
cet-14807	81	4	moriguchi	moriguchi	NOUN
cet-14807	81	5	octanol	octanol	NOUN
cet-14807	81	6	-	-	PUNCT
cet-14807	81	7	water	water	NOUN
cet-14807	81	8	partition	partition	NOUN
cet-14807	81	9	coefficient	coefficient	NOUN
cet-14807	81	10	measures	measure	VERB
cet-14807	81	11	the	the	DET
cet-14807	81	12	compound	compound	NOUN
cet-14807	81	13	solubility	solubility	NOUN
cet-14807	81	14	and	and	CCONJ
cet-14807	81	15	lipophilicity	lipophilicity	NOUN
cet-14807	81	16	.	.	PUNCT
cet-14807	82	1	the	the	DET
cet-14807	82	2	higher	high	ADJ
cet-14807	82	3	mlogp	mlogp	NOUN
cet-14807	82	4	values	value	NOUN
cet-14807	82	5	improve	improve	VERB
cet-14807	82	6	lipid	lipid	ADJ
cet-14807	82	7	membrane	membrane	NOUN
cet-14807	82	8	permeation	permeation	NOUN
cet-14807	82	9	but	but	CCONJ
cet-14807	82	10	can	can	AUX
cet-14807	82	11	hinder	hinder	VERB
cet-14807	82	12	dissolution	dissolution	NOUN
cet-14807	82	13	in	in	ADP
cet-14807	82	14	gastric	gastric	ADJ
cet-14807	82	15	or	or	CCONJ
cet-14807	82	16	intestinal	intestinal	ADJ
cet-14807	82	17	fluid	fluid	NOUN
cet-14807	82	18	,	,	PUNCT
cet-14807	82	19	affecting	affect	VERB
cet-14807	82	20	absorption	absorption	NOUN
cet-14807	82	21	(	(	PUNCT
cet-14807	82	22	lipinski	lipinski	PROPN
cet-14807	82	23	et	et	PROPN
cet-14807	82	24	al	al	PROPN
cet-14807	82	25	.	.	PROPN
cet-14807	82	26	,	,	PUNCT
cet-14807	82	27	2001	2001	NUM
cet-14807	82	28	)	)	PUNCT
cet-14807	82	29	.	.	PUNCT
cet-14807	83	1	lipinski	lipinski	PROPN
cet-14807	83	2	's	's	PART
cet-14807	83	3	1997	1997	NUM
cet-14807	83	4	publication	publication	NOUN
cet-14807	83	5	of	of	ADP
cet-14807	83	6	the	the	DET
cet-14807	83	7	'	'	PUNCT
cet-14807	83	8	rule	rule	NOUN
cet-14807	83	9	of	of	ADP
cet-14807	83	10	5	5	NUM
cet-14807	83	11	'	'	PUNCT
cet-14807	83	12	(	(	PUNCT
cet-14807	83	13	ro5	ro5	NOUN
cet-14807	83	14	)	)	PUNCT
cet-14807	83	15	stands	stand	VERB
cet-14807	83	16	as	as	ADP
cet-14807	83	17	one	one	NUM
cet-14807	83	18	of	of	ADP
cet-14807	83	19	the	the	DET
cet-14807	83	20	most	most	ADV
cet-14807	83	21	influential	influential	ADJ
cet-14807	83	22	works	work	NOUN
cet-14807	83	23	in	in	ADP
cet-14807	83	24	recent	recent	ADJ
cet-14807	83	25	medicinal	medicinal	ADJ
cet-14807	83	26	chemistry	chemistry	NOUN
cet-14807	83	27	(	(	PUNCT
cet-14807	83	28	walters	walter	NOUN
cet-14807	83	29	,	,	PUNCT
cet-14807	83	30	2012	2012	NUM
cet-14807	83	31	)	)	PUNCT
cet-14807	83	32	4	4	NUM
cet-14807	83	33	.	.	X
cet-14807	83	34	conclusion	conclusion	NOUN
cet-14807	83	35	based	base	VERB
cet-14807	83	36	on	on	ADP
cet-14807	83	37	our	our	PRON
cet-14807	83	38	simulations	simulation	NOUN
cet-14807	83	39	,	,	PUNCT
cet-14807	83	40	corchoionoside	corchoionoside	NOUN
cet-14807	83	41	c	c	PROPN
cet-14807	83	42	exhibits	exhibit	VERB
cet-14807	83	43	the	the	DET
cet-14807	83	44	highest	high	ADJ
cet-14807	83	45	binding	bind	VERB
cet-14807	83	46	affinity	affinity	NOUN
cet-14807	83	47	score	score	NOUN
cet-14807	83	48	and	and	CCONJ
cet-14807	83	49	successfully	successfully	ADV
cet-14807	83	50	passes	pass	VERB
cet-14807	83	51	both	both	CCONJ
cet-14807	83	52	the	the	DET
cet-14807	83	53	lipinski	lipinski	PROPN
cet-14807	83	54	oral	oral	ADJ
cet-14807	83	55	viability	viability	NOUN
cet-14807	83	56	test	test	NOUN
cet-14807	83	57	and	and	CCONJ
cet-14807	83	58	all	all	DET
cet-14807	83	59	admetsar	admetsar	ADJ
cet-14807	83	60	tests	test	NOUN
cet-14807	83	61	.	.	PUNCT
cet-14807	84	1	therefore	therefore	ADV
cet-14807	84	2	,	,	PUNCT
cet-14807	84	3	corchoionoside	corchoionoside	NOUN
cet-14807	84	4	c	c	PROPN
cet-14807	84	5	emerges	emerge	VERB
cet-14807	84	6	as	as	ADP
cet-14807	84	7	the	the	DET
cet-14807	84	8	most	most	ADV
cet-14807	84	9	promising	promising	ADJ
cet-14807	84	10	candidate	candidate	NOUN
cet-14807	84	11	for	for	ADP
cet-14807	84	12	a	a	DET
cet-14807	84	13	potential	potential	ADJ
cet-14807	84	14	dengue	dengue	NOUN
cet-14807	84	15	drug	drug	NOUN
cet-14807	84	16	.	.	PUNCT
cet-14807	85	1	six	six	NUM
cet-14807	85	2	of	of	ADP
cet-14807	85	3	the	the	DET
cet-14807	85	4	euphorbia	euphorbia	ADJ
cet-14807	85	5	hirta	hirta	PROPN
cet-14807	85	6	l.	l.	PROPN
cet-14807	85	7	bioactive	bioactive	PROPN
cet-14807	85	8	components	component	NOUN
cet-14807	85	9	were	be	AUX
cet-14807	85	10	identified	identify	VERB
cet-14807	85	11	as	as	ADP
cet-14807	85	12	potential	potential	ADJ
cet-14807	85	13	inhibitors	inhibitor	NOUN
cet-14807	85	14	of	of	ADP
cet-14807	85	15	the	the	DET
cet-14807	85	16	ns2b	ns2b	NOUN
cet-14807	85	17	-	-	PUNCT
cet-14807	85	18	ns3	ns3	NOUN
cet-14807	85	19	protease	protease	NOUN
cet-14807	85	20	(	(	PUNCT
cet-14807	85	21	2fom	2fom	NOUN
cet-14807	85	22	)	)	PUNCT
cet-14807	85	23	of	of	ADP
cet-14807	85	24	denv-2	denv-2	PROPN
cet-14807	85	25	:	:	PUNCT
cet-14807	85	26	corchoionoside	corchoionoside	NOUN
cet-14807	85	27	c	c	PROPN
cet-14807	85	28	(	(	PUNCT
cet-14807	85	29	-10.50	-10.50	PROPN
cet-14807	85	30	kcal	kcal	PROPN
cet-14807	85	31	/	/	SYM
cet-14807	85	32	mol	mol	NOUN
cet-14807	85	33	)	)	PUNCT
cet-14807	85	34	,	,	PUNCT
cet-14807	85	35	luteolin-7	luteolin-7	PROPN
cet-14807	85	36	-	-	PUNCT
cet-14807	85	37	o	o	NOUN
cet-14807	85	38	-	-	ADJ
cet-14807	85	39	beta	beta	NOUN
cet-14807	85	40	-	-	PUNCT
cet-14807	85	41	d	d	NOUN
cet-14807	85	42	-	-	PUNCT
cet-14807	85	43	glucopyranoside	glucopyranoside	NOUN
cet-14807	85	44	(	(	PUNCT
cet-14807	85	45	-9.05	-9.05	NOUN
cet-14807	85	46	kcal	kcal	PROPN
cet-14807	85	47	/	/	SYM
cet-14807	85	48	mol	mol	NOUN
cet-14807	85	49	)	)	PUNCT
cet-14807	85	50	,	,	PUNCT
cet-14807	85	51	corilagin	corilagin	NOUN
cet-14807	85	52	(	(	PUNCT
cet-14807	85	53	-8.55	-8.55	NUM
cet-14807	85	54	kcal	kcal	NOUN
cet-14807	85	55	/	/	SYM
cet-14807	85	56	mol	mol	NOUN
cet-14807	85	57	)	)	PUNCT
cet-14807	85	58	,	,	PUNCT
cet-14807	85	59	kaempferol-3	kaempferol-3	PROPN
cet-14807	85	60	-	-	PUNCT
cet-14807	85	61	oglucuronide	oglucuronide	NOUN
cet-14807	85	62	(	(	PUNCT
cet-14807	85	63	-8.37	-8.37	PROPN
cet-14807	85	64	kcal	kcal	PROPN
cet-14807	85	65	/	/	SYM
cet-14807	85	66	mol	mol	NOUN
cet-14807	85	67	)	)	PUNCT
cet-14807	85	68	,	,	PUNCT
cet-14807	85	69	epicatechin	epicatechin	NOUN
cet-14807	85	70	(	(	PUNCT
cet-14807	85	71	8.10	8.10	NUM
cet-14807	85	72	kcal	kcal	NOUN
cet-14807	85	73	/	/	SYM
cet-14807	85	74	mol	mol	NOUN
cet-14807	85	75	)	)	PUNCT
cet-14807	85	76	,	,	PUNCT
cet-14807	85	77	syringin	syringin	NOUN
cet-14807	85	78	(	(	PUNCT
cet-14807	85	79	-6.61	-6.61	NOUN
cet-14807	85	80	kcal	kcal	PROPN
cet-14807	85	81	/	/	SYM
cet-14807	85	82	mol	mol	NOUN
cet-14807	85	83	)	)	PUNCT
cet-14807	85	84	.	.	PUNCT
cet-14807	86	1	these	these	DET
cet-14807	86	2	compounds	compound	NOUN
cet-14807	86	3	are	be	AUX
cet-14807	86	4	proven	prove	VERB
cet-14807	86	5	to	to	PART
cet-14807	86	6	bind	bind	VERB
cet-14807	86	7	at	at	ADP
cet-14807	86	8	the	the	DET
cet-14807	86	9	catalytic	catalytic	ADJ
cet-14807	86	10	triad	triad	NUM
cet-14807	86	11	of	of	ADP
cet-14807	86	12	the	the	DET
cet-14807	86	13	protease	protease	NOUN
cet-14807	86	14	through	through	ADP
cet-14807	86	15	hydrogen	hydrogen	NOUN
cet-14807	86	16	bonding	bonding	NOUN
cet-14807	86	17	with	with	ADP
cet-14807	86	18	high	high	ADJ
cet-14807	86	19	binding	bind	VERB
cet-14807	86	20	affinities	affinity	NOUN
cet-14807	86	21	.	.	PUNCT
cet-14807	87	1	only	only	ADV
cet-14807	87	2	three	three	NUM
cet-14807	87	3	bioactive	bioactive	ADJ
cet-14807	87	4	components	component	NOUN
cet-14807	87	5	(	(	PUNCT
cet-14807	87	6	corchoionoside	corchoionoside	NOUN
cet-14807	87	7	c	c	NOUN
cet-14807	87	8	,	,	PUNCT
cet-14807	87	9	epicatechin	epicatechin	NOUN
cet-14807	87	10	,	,	PUNCT
cet-14807	87	11	and	and	CCONJ
cet-14807	87	12	syringin	syringin	VERB
cet-14807	87	13	)	)	PUNCT
cet-14807	87	14	have	have	AUX
cet-14807	87	15	passed	pass	VERB
cet-14807	87	16	the	the	DET
cet-14807	87	17	lipinski	lipinski	PROPN
cet-14807	87	18	test	test	NOUN
cet-14807	87	19	,	,	PUNCT
cet-14807	87	20	blood	blood	NOUN
cet-14807	87	21	-	-	PUNCT
cet-14807	87	22	brain	brain	NOUN
cet-14807	87	23	barrier	barrier	NOUN
cet-14807	87	24	,	,	PUNCT
cet-14807	87	25	and	and	CCONJ
cet-14807	87	26	toxicity	toxicity	NOUN
cet-14807	87	27	analysis	analysis	NOUN
cet-14807	87	28	while	while	SCONJ
cet-14807	87	29	the	the	DET
cet-14807	87	30	other	other	ADJ
cet-14807	87	31	three	three	NUM
cet-14807	87	32	bioactive	bioactive	ADJ
cet-14807	87	33	components	component	NOUN
cet-14807	87	34	(	(	PUNCT
cet-14807	87	35	luteolin-7	luteolin-7	NOUN
cet-14807	87	36	-	-	PUNCT
cet-14807	87	37	o	o	NOUN
cet-14807	87	38	-	-	ADJ
cet-14807	87	39	beta	beta	NOUN
cet-14807	87	40	-	-	PUNCT
cet-14807	87	41	dglucopyranoside	dglucopyranoside	NOUN
cet-14807	87	42	,	,	PUNCT
cet-14807	87	43	corilagin	corilagin	NOUN
cet-14807	87	44	,	,	PUNCT
cet-14807	87	45	kaempferol-3	kaempferol-3	PROPN
cet-14807	87	46	-	-	PUNCT
cet-14807	87	47	o	o	NOUN
cet-14807	87	48	-	-	ADJ
cet-14807	87	49	glucuronide	glucuronide	NOUN
cet-14807	87	50	)	)	PUNCT
cet-14807	87	51	have	have	AUX
cet-14807	87	52	not	not	PART
cet-14807	87	53	passed	pass	VERB
cet-14807	87	54	the	the	DET
cet-14807	87	55	lipinski	lipinski	PROPN
cet-14807	87	56	test	test	NOUN
cet-14807	87	57	but	but	CCONJ
cet-14807	87	58	passed	pass	VERB
cet-14807	87	59	the	the	DET
cet-14807	87	60	blood	blood	NOUN
cet-14807	87	61	-	-	PUNCT
cet-14807	87	62	brain	brain	NOUN
cet-14807	87	63	barrier	barrier	NOUN
cet-14807	87	64	and	and	CCONJ
cet-14807	87	65	toxicity	toxicity	NOUN
cet-14807	87	66	analysis	analysis	NOUN
cet-14807	87	67	.	.	PUNCT
cet-14807	88	1	this	this	PRON
cet-14807	88	2	means	mean	VERB
cet-14807	88	3	the	the	DET
cet-14807	88	4	latter	latter	ADJ
cet-14807	88	5	3	3	NUM
cet-14807	88	6	bioactive	bioactive	NOUN
cet-14807	88	7	components	component	NOUN
cet-14807	88	8	would	would	AUX
cet-14807	88	9	only	only	ADV
cet-14807	88	10	be	be	AUX
cet-14807	88	11	administered	administer	VERB
cet-14807	88	12	through	through	ADP
cet-14807	88	13	injection	injection	NOUN
cet-14807	88	14	within	within	ADP
cet-14807	88	15	the	the	DET
cet-14807	88	16	human	human	ADJ
cet-14807	88	17	body	body	NOUN
cet-14807	88	18	.	.	PUNCT
cet-14807	89	1	other	other	ADJ
cet-14807	89	2	bioactive	bioactive	ADJ
cet-14807	89	3	components	component	NOUN
cet-14807	89	4	from	from	ADP
cet-14807	89	5	euphorbia	euphorbia	PROPN
cet-14807	89	6	hirta	hirta	PROPN
cet-14807	89	7	l.	l.	PROPN
cet-14807	89	8	should	should	AUX
cet-14807	89	9	still	still	ADV
cet-14807	89	10	be	be	AUX
cet-14807	89	11	considered	consider	VERB
cet-14807	89	12	.	.	PUNCT
cet-14807	90	1	lipinski	lipinski	PROPN
cet-14807	90	2	analysis	analysis	NOUN
cet-14807	90	3	applies	apply	VERB
cet-14807	90	4	only	only	ADV
cet-14807	90	5	to	to	ADP
cet-14807	90	6	oral	oral	ADJ
cet-14807	90	7	absorption	absorption	NOUN
cet-14807	90	8	,	,	PUNCT
cet-14807	90	9	so	so	CCONJ
cet-14807	90	10	other	other	ADJ
cet-14807	90	11	administration	administration	NOUN
cet-14807	90	12	routes	route	NOUN
cet-14807	90	13	like	like	ADP
cet-14807	90	14	injection	injection	NOUN
cet-14807	90	15	are	be	AUX
cet-14807	90	16	possible	possible	ADJ
cet-14807	90	17	.	.	PUNCT
cet-14807	91	1	for	for	ADP
cet-14807	91	2	the	the	DET
cet-14807	91	3	bbb	bbb	PROPN
cet-14807	91	4	,	,	PUNCT
cet-14807	91	5	unless	unless	SCONJ
cet-14807	91	6	the	the	DET
cet-14807	91	7	target	target	NOUN
cet-14807	91	8	is	be	AUX
cet-14807	91	9	the	the	DET
cet-14807	91	10	central	central	ADJ
cet-14807	91	11	nervous	nervous	ADJ
cet-14807	91	12	system	system	NOUN
cet-14807	91	13	the	the	DET
cet-14807	91	14	blood	blood	NOUN
cet-14807	91	15	-	-	PUNCT
cet-14807	91	16	brain	brain	NOUN
cet-14807	91	17	barrier	barrier	NOUN
cet-14807	91	18	value	value	NOUN
cet-14807	91	19	should	should	AUX
cet-14807	91	20	be	be	AUX
cet-14807	91	21	negative	negative	ADJ
cet-14807	91	22	.	.	PUNCT
cet-14807	92	1	further	further	ADJ
cet-14807	92	2	research	research	NOUN
cet-14807	92	3	must	must	AUX
cet-14807	92	4	be	be	AUX
cet-14807	92	5	verified	verify	VERB
cet-14807	92	6	if	if	SCONJ
cet-14807	92	7	these	these	DET
cet-14807	92	8	six	six	NUM
cet-14807	92	9	bioactive	bioactive	ADJ
cet-14807	92	10	components	component	NOUN
cet-14807	92	11	can	can	AUX
cet-14807	92	12	inhibit	inhibit	VERB
cet-14807	92	13	the	the	DET
cet-14807	92	14	ns2bns3	ns2bns3	PROPN
cet-14807	92	15	protease	protease	NOUN
cet-14807	92	16	of	of	ADP
cet-14807	92	17	denv-2	denv-2	PROPN
cet-14807	92	18	through	through	ADP
cet-14807	92	19	clinical	clinical	ADJ
cet-14807	92	20	trials	trial	NOUN
cet-14807	92	21	whether	whether	SCONJ
cet-14807	92	22	it	it	PRON
cet-14807	92	23	is	be	AUX
cet-14807	92	24	in	in	ADV
cet-14807	92	25	-	-	PUNCT
cet-14807	92	26	vitro	vitro	X
cet-14807	92	27	or	or	CCONJ
cet-14807	92	28	in	in	ADP
cet-14807	92	29	-	-	PUNCT
cet-14807	92	30	vivo	vivo	NOUN
cet-14807	92	31	and	and	CCONJ
cet-14807	92	32	examine	examine	VERB
cet-14807	92	33	other	other	ADJ
cet-14807	92	34	possibilities	possibility	NOUN
cet-14807	92	35	of	of	ADP
cet-14807	92	36	drug	drug	NOUN
cet-14807	92	37	-	-	PUNCT
cet-14807	92	38	likeness	likeness	NOUN
cet-14807	92	39	in	in	ADP
cet-14807	92	40	the	the	DET
cet-14807	92	41	bioactive	bioactive	ADJ
cet-14807	92	42	components	component	NOUN
cet-14807	92	43	of	of	ADP
cet-14807	92	44	euphorbia	euphorbia	ADJ
cet-14807	92	45	hirta	hirta	PROPN
cet-14807	92	46	l.	l.	PROPN
cet-14807	92	47	references	references	PROPN
cet-14807	92	48	alqahtani	alqahtani	PROPN
cet-14807	92	49	,	,	PUNCT
cet-14807	92	50	s.	s.	PROPN
cet-14807	92	51	,	,	PUNCT
cet-14807	92	52	2017	2017	NUM
cet-14807	92	53	,	,	PUNCT
cet-14807	92	54	in	in	ADP
cet-14807	92	55	silico	silico	NOUN
cet-14807	92	56	adme	adme	NOUN
cet-14807	92	57	-	-	PUNCT
cet-14807	92	58	tox	tox	NOUN
cet-14807	92	59	modeling	modeling	NOUN
cet-14807	92	60	:	:	PUNCT
cet-14807	92	61	progress	progress	NOUN
cet-14807	92	62	and	and	CCONJ
cet-14807	92	63	prospects	prospect	NOUN
cet-14807	92	64	.	.	PUNCT
cet-14807	93	1	expert	expert	ADJ
cet-14807	93	2	opinion	opinion	NOUN
cet-14807	93	3	on	on	ADP
cet-14807	93	4	drug	drug	NOUN
cet-14807	93	5	metabolism	metabolism	NOUN
cet-14807	93	6	and	and	CCONJ
cet-14807	93	7	toxicology	toxicology	NOUN
cet-14807	93	8	,	,	PUNCT
cet-14807	93	9	13(11	13(11	NUM
cet-14807	93	10	)	)	PUNCT
cet-14807	93	11	,	,	PUNCT
cet-14807	93	12	1147	1147	NUM
cet-14807	93	13	-	-	SYM
cet-14807	93	14	1158	1158	NUM
cet-14807	93	15	.	.	PUNCT
cet-14807	94	1	71	71	NUM
cet-14807	94	2	cayona	cayona	NOUN
cet-14807	94	3	,	,	PUNCT
cet-14807	94	4	r.	r.	PROPN
cet-14807	94	5	,	,	PUNCT
cet-14807	94	6	creencia	creencia	PROPN
cet-14807	94	7	,	,	PUNCT
cet-14807	94	8	e.	e.	PROPN
cet-14807	94	9	c.	c.	PROPN
cet-14807	94	10	,	,	PUNCT
cet-14807	94	11	2022	2022	NUM
cet-14807	94	12	,	,	PUNCT
cet-14807	94	13	phytochemicals	phytochemical	NOUN
cet-14807	94	14	of	of	ADP
cet-14807	94	15	euphorbia	euphorbia	ADJ
cet-14807	94	16	hirta	hirta	PROPN
cet-14807	94	17	l.	l.	PROPN
cet-14807	94	18	and	and	CCONJ
cet-14807	94	19	their	their	PRON
cet-14807	94	20	inhibitory	inhibitory	ADJ
cet-14807	94	21	potential	potential	NOUN
cet-14807	94	22	against	against	ADP
cet-14807	94	23	sars	sar	NOUN
cet-14807	94	24	-	-	PUNCT
cet-14807	94	25	cov-2	cov-2	NOUN
cet-14807	94	26	main	main	ADJ
cet-14807	94	27	protease	protease	NOUN
cet-14807	94	28	,	,	PUNCT
cet-14807	94	29	frontiers	frontier	NOUN
cet-14807	94	30	in	in	ADP
cet-14807	94	31	molecular	molecular	ADJ
cet-14807	94	32	biosciences	bioscience	NOUN
cet-14807	94	33	,	,	PUNCT
cet-14807	94	34	8,801401	8,801401	NUM
cet-14807	94	35	.	.	PUNCT
cet-14807	95	1	calderón	calderón	NOUN
cet-14807	95	2	-	-	ADJ
cet-14807	95	3	peláez	peláez	ADJ
cet-14807	95	4	,	,	PUNCT
cet-14807	95	5	m.	m.	NOUN
cet-14807	95	6	a.	a.	PROPN
cet-14807	95	7	,	,	PUNCT
cet-14807	95	8	velandia	velandia	NOUN
cet-14807	95	9	-	-	PUNCT
cet-14807	95	10	romero	romero	PROPN
cet-14807	95	11	,	,	PUNCT
cet-14807	95	12	m.	m.	NOUN
cet-14807	95	13	l.	l.	PROPN
cet-14807	95	14	,	,	PUNCT
cet-14807	95	15	bastidas	bastidas	PROPN
cet-14807	95	16	-	-	PUNCT
cet-14807	95	17	legarda	legarda	NOUN
cet-14807	95	18	,	,	PUNCT
cet-14807	95	19	l.	l.	PROPN
cet-14807	95	20	y.	y.	PROPN
cet-14807	95	21	,	,	PUNCT
cet-14807	95	22	beltrán	beltrán	NOUN
cet-14807	95	23	,	,	PUNCT
cet-14807	95	24	e.	e.	PROPN
cet-14807	95	25	o.	o.	PROPN
cet-14807	95	26	,	,	PUNCT
cet-14807	95	27	camacho	camacho	PROPN
cet-14807	95	28	-	-	PUNCT
cet-14807	95	29	ortega	ortega	PROPN
cet-14807	95	30	,	,	PUNCT
cet-14807	95	31	s.	s.	PROPN
cet-14807	95	32	j.	j.	PROPN
cet-14807	95	33	,	,	PUNCT
cet-14807	95	34	castellanos	castellanos	PROPN
cet-14807	95	35	,	,	PUNCT
cet-14807	95	36	j.	j.	PROPN
cet-14807	95	37	e.	e.	PROPN
cet-14807	95	38	,	,	PUNCT
cet-14807	95	39	2019	2019	NUM
cet-14807	95	40	,	,	PUNCT
cet-14807	95	41	dengue	dengue	NOUN
cet-14807	95	42	virus	virus	NOUN
cet-14807	95	43	infection	infection	NOUN
cet-14807	95	44	of	of	ADP
cet-14807	95	45	blood	blood	NOUN
cet-14807	95	46	-	-	PUNCT
cet-14807	95	47	brain	brain	NOUN
cet-14807	95	48	barrier	barrier	NOUN
cet-14807	95	49	cells	cell	NOUN
cet-14807	95	50	:	:	PUNCT
cet-14807	95	51	consequences	consequence	NOUN
cet-14807	95	52	of	of	ADP
cet-14807	95	53	severe	severe	ADJ
cet-14807	95	54	disease	disease	NOUN
cet-14807	95	55	,	,	PUNCT
cet-14807	95	56	frontiers	frontier	NOUN
cet-14807	95	57	in	in	ADP
cet-14807	95	58	microbiology	microbiology	NOUN
cet-14807	95	59	,	,	PUNCT
cet-14807	95	60	10,31293558	10,31293558	NUM
cet-14807	95	61	.	.	PUNCT
cet-14807	96	1	farzaei	farzaei	PROPN
cet-14807	96	2	m.	m.	PROPN
cet-14807	96	3	h.	h.	PROPN
cet-14807	96	4	,	,	PUNCT
cet-14807	96	5	bayrami	bayrami	PROPN
cet-14807	96	6	z.	z.	PROPN
cet-14807	96	7	,	,	PUNCT
cet-14807	96	8	farzaei	farzaei	PROPN
cet-14807	96	9	f.	f.	PROPN
cet-14807	96	10	,	,	PUNCT
cet-14807	96	11	aneva	aneva	PROPN
cet-14807	96	12	i.	i.	PROPN
cet-14807	96	13	,	,	PUNCT
cet-14807	96	14	das	das	PROPN
cet-14807	96	15	s.	s.	PROPN
cet-14807	96	16	k.	k.	PROPN
cet-14807	96	17	,	,	PUNCT
cet-14807	96	18	patra	patra	PROPN
cet-14807	96	19	j.	j.	PROPN
cet-14807	96	20	k.	k.	PROPN
cet-14807	96	21	,	,	PUNCT
cet-14807	96	22	das	das	PROPN
cet-14807	96	23	g.	g.	PROPN
cet-14807	96	24	,	,	PUNCT
cet-14807	96	25	abdollahi	abdollahi	ADJ
cet-14807	96	26	m.	m.	NOUN
cet-14807	96	27	,	,	PUNCT
cet-14807	96	28	2020	2020	NUM
cet-14807	96	29	,	,	PUNCT
cet-14807	96	30	poisoning	poisoning	NOUN
cet-14807	96	31	by	by	ADP
cet-14807	96	32	medicinal	medicinal	ADJ
cet-14807	96	33	plants	plant	NOUN
cet-14807	96	34	.	.	PUNCT
cet-14807	97	1	archives	archive	NOUN
cet-14807	97	2	of	of	ADP
cet-14807	97	3	iranian	iranian	ADJ
cet-14807	97	4	medicine	medicine	NOUN
cet-14807	97	5	,	,	PUNCT
cet-14807	97	6	23(2	23(2	NOUN
cet-14807	97	7	)	)	PUNCT
cet-14807	97	8	,	,	PUNCT
cet-14807	97	9	117	117	NUM
cet-14807	97	10	-	-	SYM
cet-14807	97	11	127	127	NUM
cet-14807	97	12	.	.	PUNCT
cet-14807	98	1	forli	forli	PROPN
cet-14807	98	2	,	,	PUNCT
cet-14807	98	3	s.	s.	PROPN
cet-14807	98	4	,	,	PUNCT
cet-14807	98	5	huey	huey	PROPN
cet-14807	98	6	,	,	PUNCT
cet-14807	98	7	r.	r.	PROPN
cet-14807	98	8	,	,	PUNCT
cet-14807	98	9	pique	pique	NOUN
cet-14807	98	10	,	,	PUNCT
cet-14807	98	11	m.	m.	PROPN
cet-14807	98	12	e.	e.	PROPN
cet-14807	98	13	,	,	PUNCT
cet-14807	98	14	sanner	sanner	NOUN
cet-14807	98	15	,	,	PUNCT
cet-14807	98	16	m.	m.	NOUN
cet-14807	98	17	f.	f.	PROPN
cet-14807	98	18	,	,	PUNCT
cet-14807	98	19	goodsell	goodsell	PROPN
cet-14807	98	20	,	,	PUNCT
cet-14807	98	21	d.	d.	PROPN
cet-14807	98	22	s.	s.	PROPN
cet-14807	98	23	,	,	PUNCT
cet-14807	98	24	olson	olson	PROPN
cet-14807	98	25	,	,	PUNCT
cet-14807	98	26	a.	a.	PROPN
cet-14807	98	27	j.	j.	PROPN
cet-14807	98	28	,	,	PUNCT
cet-14807	98	29	2016	2016	NUM
cet-14807	98	30	,	,	PUNCT
cet-14807	98	31	computational	computational	ADJ
cet-14807	98	32	protein	protein	NOUN
cet-14807	98	33	-	-	PUNCT
cet-14807	98	34	ligand	ligand	NOUN
cet-14807	98	35	docking	docking	NOUN
cet-14807	98	36	and	and	CCONJ
cet-14807	98	37	virtual	virtual	ADJ
cet-14807	98	38	drug	drug	NOUN
cet-14807	98	39	screening	screening	NOUN
cet-14807	98	40	with	with	ADP
cet-14807	98	41	the	the	DET
cet-14807	98	42	autodock	autodock	NOUN
cet-14807	98	43	suite	suite	PROPN
cet-14807	98	44	.	.	PUNCT
cet-14807	99	1	nature	nature	PROPN
cet-14807	99	2	protocols	protocol	NOUN
cet-14807	99	3	,	,	PUNCT
cet-14807	99	4	11(5	11(5	NUM
cet-14807	99	5	)	)	PUNCT
cet-14807	99	6	,	,	PUNCT
cet-14807	99	7	905–919	905–919	NUM
cet-14807	99	8	.	.	PUNCT
cet-14807	100	1	gaillard	gaillard	PROPN
cet-14807	100	2	,	,	PUNCT
cet-14807	100	3	t.	t.	PROPN
cet-14807	100	4	,	,	PUNCT
cet-14807	100	5	2018	2018	NUM
cet-14807	100	6	,	,	PUNCT
cet-14807	100	7	evaluation	evaluation	NOUN
cet-14807	100	8	of	of	ADP
cet-14807	100	9	autodock	autodock	NOUN
cet-14807	100	10	and	and	CCONJ
cet-14807	100	11	autodock	autodock	NOUN
cet-14807	100	12	vina	vina	NOUN
cet-14807	100	13	on	on	ADP
cet-14807	100	14	the	the	DET
cet-14807	100	15	casf-2013	casf-2013	ADJ
cet-14807	100	16	benchmark	benchmark	NOUN
cet-14807	100	17	.	.	PUNCT
cet-14807	101	1	journal	journal	PROPN
cet-14807	101	2	of	of	ADP
cet-14807	101	3	chemical	chemical	ADJ
cet-14807	101	4	information	information	NOUN
cet-14807	101	5	and	and	CCONJ
cet-14807	101	6	modeling	modeling	NOUN
cet-14807	101	7	,	,	PUNCT
cet-14807	101	8	58	58	NUM
cet-14807	101	9	(	(	PUNCT
cet-14807	101	10	8)	8)	NUM
cet-14807	101	11	,	,	PUNCT
cet-14807	101	12	1697	1697	NUM
cet-14807	101	13	-	-	SYM
cet-14807	101	14	1706	1706	NUM
cet-14807	101	15	.	.	PUNCT
cet-14807	102	1	hapuarachchi	hapuarachchi	PROPN
cet-14807	102	2	,	,	PUNCT
cet-14807	102	3	h.	h.	PROPN
cet-14807	102	4	c.	c.	PROPN
cet-14807	102	5	,	,	PUNCT
cet-14807	102	6	chua	chua	PROPN
cet-14807	102	7	,	,	PUNCT
cet-14807	102	8	r.	r.	PROPN
cet-14807	102	9	c.	c.	PROPN
cet-14807	102	10	,	,	PUNCT
cet-14807	102	11	shi	shi	PROPN
cet-14807	102	12	,	,	PUNCT
cet-14807	102	13	y.	y.	PROPN
cet-14807	102	14	,	,	PUNCT
cet-14807	102	15	thein	thein	PROPN
cet-14807	102	16	,	,	PUNCT
cet-14807	102	17	t.	t.	PROPN
cet-14807	102	18	l.	l.	PROPN
cet-14807	102	19	,	,	PUNCT
cet-14807	102	20	lee	lee	PROPN
cet-14807	102	21	,	,	PUNCT
cet-14807	102	22	l.	l.	PROPN
cet-14807	102	23	k.	k.	PROPN
cet-14807	102	24	,	,	PUNCT
cet-14807	102	25	lee	lee	PROPN
cet-14807	102	26	,	,	PUNCT
cet-14807	102	27	k.	k.	PROPN
cet-14807	102	28	s.	s.	PROPN
cet-14807	102	29	,	,	PUNCT
cet-14807	102	30	lye	lye	PROPN
cet-14807	102	31	,	,	PUNCT
cet-14807	102	32	d.	d.	PROPN
cet-14807	102	33	c.	c.	PROPN
cet-14807	102	34	,	,	PUNCT
cet-14807	102	35	ng	ng	PROPN
cet-14807	102	36	,	,	PUNCT
cet-14807	102	37	l.	l.	PROPN
cet-14807	102	38	c.	c.	PROPN
cet-14807	102	39	,	,	PUNCT
cet-14807	102	40	leo	leo	PROPN
cet-14807	102	41	,	,	PUNCT
cet-14807	102	42	y.	y.	PROPN
cet-14807	102	43	s.	s.	PROPN
cet-14807	102	44	,	,	PUNCT
cet-14807	102	45	2015	2015	NUM
cet-14807	102	46	,	,	PUNCT
cet-14807	102	47	clinical	clinical	ADJ
cet-14807	102	48	outcome	outcome	NOUN
cet-14807	102	49	and	and	CCONJ
cet-14807	102	50	genetic	genetic	ADJ
cet-14807	102	51	differences	difference	NOUN
cet-14807	102	52	within	within	ADP
cet-14807	102	53	a	a	DET
cet-14807	102	54	monophyletic	monophyletic	ADJ
cet-14807	102	55	dengue	dengue	NOUN
cet-14807	102	56	virus	virus	NOUN
cet-14807	102	57	type	type	NOUN
cet-14807	102	58	2	2	NUM
cet-14807	102	59	population	population	NOUN
cet-14807	102	60	,	,	PUNCT
cet-14807	102	61	plos	plos	PROPN
cet-14807	102	62	one	one	NUM
cet-14807	102	63	,	,	PUNCT
cet-14807	102	64	10(3),e0121696	10(3),e0121696	NUM
cet-14807	102	65	.	.	PUNCT
cet-14807	103	1	kumar	kumar	PROPN
cet-14807	103	2	,	,	PUNCT
cet-14807	103	3	s.	s.	PROPN
cet-14807	103	4	,	,	PUNCT
cet-14807	103	5	malhotra	malhotra	PROPN
cet-14807	103	6	,	,	PUNCT
cet-14807	103	7	r.	r.	PROPN
cet-14807	103	8	,	,	PUNCT
cet-14807	103	9	kumar	kumar	PROPN
cet-14807	103	10	,	,	PUNCT
cet-14807	103	11	d.	d.	PROPN
cet-14807	103	12	,	,	PUNCT
cet-14807	103	13	2010	2010	NUM
cet-14807	103	14	,	,	PUNCT
cet-14807	103	15	euphorbia	euphorbia	PROPN
cet-14807	103	16	hirta	hirta	PROPN
cet-14807	103	17	:	:	PUNCT
cet-14807	103	18	its	its	PRON
cet-14807	103	19	chemistry	chemistry	NOUN
cet-14807	103	20	,	,	PUNCT
cet-14807	103	21	traditional	traditional	ADJ
cet-14807	103	22	and	and	CCONJ
cet-14807	103	23	medicinal	medicinal	ADJ
cet-14807	103	24	uses	use	NOUN
cet-14807	103	25	,	,	PUNCT
cet-14807	103	26	and	and	CCONJ
cet-14807	103	27	pharmacological	pharmacological	ADJ
cet-14807	103	28	activities	activity	NOUN
cet-14807	103	29	,	,	PUNCT
cet-14807	103	30	pharmacognosy	pharmacognosy	NOUN
cet-14807	103	31	reviews	review	NOUN
cet-14807	103	32	,	,	PUNCT
cet-14807	103	33	4(7	4(7	NUM
cet-14807	103	34	)	)	PUNCT
cet-14807	103	35	,	,	PUNCT
cet-14807	103	36	58	58	NUM
cet-14807	103	37	.	.	PUNCT
cet-14807	104	1	laina	laina	PROPN
cet-14807	104	2	k.m	k.m	PROPN
cet-14807	104	3	.	.	PROPN
cet-14807	104	4	,	,	PUNCT
cet-14807	104	5	eleni	eleni	PROPN
cet-14807	104	6	p.n	p.n	PROPN
cet-14807	104	7	.	.	PROPN
cet-14807	104	8	,	,	PUNCT
cet-14807	104	9	tsitseli	tsitseli	PROPN
cet-14807	104	10	k.g	k.g	PROPN
cet-14807	104	11	.	.	PROPN
cet-14807	104	12	,	,	PUNCT
cet-14807	104	13	krokida	krokida	PROPN
cet-14807	104	14	m.k	m.k	PROPN
cet-14807	104	15	.	.	PROPN
cet-14807	104	16	,	,	PUNCT
cet-14807	104	17	2021	2021	NUM
cet-14807	104	18	,	,	PUNCT
cet-14807	104	19	process	process	NOUN
cet-14807	104	20	design	design	NOUN
cet-14807	104	21	for	for	ADP
cet-14807	104	22	the	the	DET
cet-14807	104	23	extraction	extraction	NOUN
cet-14807	104	24	of	of	ADP
cet-14807	104	25	bioactive	bioactive	ADJ
cet-14807	104	26	compounds	compound	NOUN
cet-14807	104	27	from	from	ADP
cet-14807	104	28	several	several	ADJ
cet-14807	104	29	mediterranean	mediterranean	ADJ
cet-14807	104	30	medicinal	medicinal	ADJ
cet-14807	104	31	plants	plant	NOUN
cet-14807	104	32	,	,	PUNCT
cet-14807	104	33	chemical	chemical	NOUN
cet-14807	104	34	engineering	engineering	NOUN
cet-14807	104	35	transactions	transaction	NOUN
cet-14807	104	36	,	,	PUNCT
cet-14807	104	37	86	86	NUM
cet-14807	104	38	,	,	PUNCT
cet-14807	104	39	13271332	13271332	NUM
cet-14807	104	40	.	.	PUNCT
cet-14807	105	1	lipinski	lipinski	PROPN
cet-14807	105	2	,	,	PUNCT
cet-14807	105	3	c.	c.	PROPN
cet-14807	105	4	a.	a.	PROPN
cet-14807	105	5	,	,	PUNCT
cet-14807	105	6	lombardo	lombardo	PROPN
cet-14807	105	7	,	,	PUNCT
cet-14807	105	8	f.	f.	PROPN
cet-14807	105	9	,	,	PUNCT
cet-14807	105	10	dominy	dominy	PROPN
cet-14807	105	11	,	,	PUNCT
cet-14807	105	12	b.	b.	PROPN
cet-14807	105	13	w.	w.	PROPN
cet-14807	105	14	,	,	PUNCT
cet-14807	105	15	feeney	feeney	PROPN
cet-14807	105	16	,	,	PUNCT
cet-14807	105	17	p.	p.	PROPN
cet-14807	105	18	j.	j.	PROPN
cet-14807	105	19	,	,	PUNCT
cet-14807	105	20	2001	2001	NUM
cet-14807	105	21	,	,	PUNCT
cet-14807	105	22	experimental	experimental	ADJ
cet-14807	105	23	and	and	CCONJ
cet-14807	105	24	computational	computational	ADJ
cet-14807	105	25	approaches	approach	NOUN
cet-14807	105	26	to	to	PART
cet-14807	105	27	estimate	estimate	VERB
cet-14807	105	28	solubility	solubility	NOUN
cet-14807	105	29	and	and	CCONJ
cet-14807	105	30	permeability	permeability	NOUN
cet-14807	105	31	in	in	ADP
cet-14807	105	32	drug	drug	NOUN
cet-14807	105	33	discovery	discovery	NOUN
cet-14807	105	34	and	and	CCONJ
cet-14807	105	35	development	development	NOUN
cet-14807	105	36	settings	setting	NOUN
cet-14807	105	37	,	,	PUNCT
cet-14807	105	38	advanced	advanced	ADJ
cet-14807	105	39	drug	drug	NOUN
cet-14807	105	40	delivery	delivery	NOUN
cet-14807	105	41	reviews	review	NOUN
cet-14807	105	42	,	,	PUNCT
cet-14807	105	43	46(1	46(1	NUM
cet-14807	105	44	-	-	SYM
cet-14807	105	45	3	3	NUM
cet-14807	105	46	)	)	PUNCT
cet-14807	105	47	,	,	PUNCT
cet-14807	105	48	3–26	3–26	NUM
cet-14807	105	49	.	.	PUNCT
cet-14807	106	1	nanaware	nanaware	PROPN
cet-14807	106	2	,	,	PUNCT
cet-14807	106	3	n.	n.	NOUN
cet-14807	106	4	,	,	PUNCT
cet-14807	106	5	banerjee	banerjee	PROPN
cet-14807	106	6	,	,	PUNCT
cet-14807	106	7	a.	a.	NOUN
cet-14807	106	8	,	,	PUNCT
cet-14807	106	9	bagchi	bagchi	PROPN
cet-14807	106	10	,	,	PUNCT
cet-14807	106	11	s.	s.	PROPN
cet-14807	106	12	m.	m.	PROPN
cet-14807	106	13	,	,	PUNCT
cet-14807	106	14	bagchi	bagchi	NOUN
cet-14807	106	15	,	,	PUNCT
cet-14807	106	16	p.	p.	NOUN
cet-14807	106	17	,	,	PUNCT
cet-14807	106	18	mukherjee	mukherjee	PROPN
cet-14807	106	19	,	,	PUNCT
cet-14807	106	20	a.	a.	NOUN
cet-14807	106	21	,	,	PUNCT
cet-14807	106	22	2021	2021	NUM
cet-14807	106	23	,	,	PUNCT
cet-14807	106	24	dengue	dengue	NOUN
cet-14807	106	25	virus	virus	NOUN
cet-14807	106	26	infection	infection	NOUN
cet-14807	106	27	:	:	PUNCT
cet-14807	106	28	a	a	DET
cet-14807	106	29	tale	tale	NOUN
cet-14807	106	30	of	of	ADP
cet-14807	106	31	viral	viral	ADJ
cet-14807	106	32	exploitations	exploitation	NOUN
cet-14807	106	33	and	and	CCONJ
cet-14807	106	34	host	host	NOUN
cet-14807	106	35	responses	response	NOUN
cet-14807	106	36	,	,	PUNCT
cet-14807	106	37	viruses	virus	NOUN
cet-14807	106	38	,	,	PUNCT
cet-14807	106	39	13(10	13(10	NUM
cet-14807	106	40	)	)	PUNCT
cet-14807	106	41	,	,	PUNCT
cet-14807	106	42	1967	1967	NUM
cet-14807	106	43	.	.	PUNCT
cet-14807	107	1	persidsky	persidsky	NOUN
cet-14807	107	2	,	,	PUNCT
cet-14807	107	3	y.	y.	PROPN
cet-14807	107	4	,	,	PUNCT
cet-14807	107	5	ramirez	ramirez	PROPN
cet-14807	107	6	,	,	PUNCT
cet-14807	107	7	s.	s.	PROPN
cet-14807	107	8	h.	h.	PROPN
cet-14807	107	9	,	,	PUNCT
cet-14807	107	10	haorah	haorah	PROPN
cet-14807	107	11	,	,	PUNCT
cet-14807	107	12	j.	j.	PROPN
cet-14807	107	13	,	,	PUNCT
cet-14807	107	14	kanmogne	kanmogne	PROPN
cet-14807	107	15	,	,	PUNCT
cet-14807	107	16	g.	g.	PROPN
cet-14807	107	17	d.	d.	PROPN
cet-14807	107	18	,	,	PUNCT
cet-14807	107	19	2006	2006	NUM
cet-14807	107	20	,	,	PUNCT
cet-14807	107	21	blood	blood	NOUN
cet-14807	107	22	-	-	PUNCT
cet-14807	107	23	brain	brain	NOUN
cet-14807	107	24	barrier	barrier	NOUN
cet-14807	107	25	:	:	PUNCT
cet-14807	107	26	structural	structural	ADJ
cet-14807	107	27	components	component	NOUN
cet-14807	107	28	and	and	CCONJ
cet-14807	107	29	function	function	NOUN
cet-14807	107	30	under	under	ADP
cet-14807	107	31	physiologic	physiologic	ADJ
cet-14807	107	32	and	and	CCONJ
cet-14807	107	33	pathologic	pathologic	ADJ
cet-14807	107	34	conditions	condition	NOUN
cet-14807	107	35	,	,	PUNCT
cet-14807	107	36	journal	journal	NOUN
cet-14807	107	37	of	of	ADP
cet-14807	107	38	neuroimmune	neuroimmune	PROPN
cet-14807	107	39	pharmacology	pharmacology	NOUN
cet-14807	107	40	:	:	PUNCT
cet-14807	107	41	the	the	DET
cet-14807	107	42	official	official	ADJ
cet-14807	107	43	journal	journal	NOUN
cet-14807	107	44	of	of	ADP
cet-14807	107	45	the	the	DET
cet-14807	107	46	society	society	NOUN
cet-14807	107	47	on	on	ADP
cet-14807	107	48	neuro	neuro	PROPN
cet-14807	107	49	immune	immune	ADJ
cet-14807	107	50	pharmacology	pharmacology	NOUN
cet-14807	107	51	,	,	PUNCT
cet-14807	107	52	1(3	1(3	NUM
cet-14807	107	53	)	)	PUNCT
cet-14807	107	54	,	,	PUNCT
cet-14807	107	55	223–236	223–236	NUM
cet-14807	107	56	.	.	PUNCT
cet-14807	107	57	ruswanto	ruswanto	PROPN
cet-14807	107	58	,	,	PUNCT
cet-14807	107	59	r.	r.	PROPN
cet-14807	107	60	,	,	PUNCT
cet-14807	107	61	mardianingrum	mardianingrum	PROPN
cet-14807	107	62	,	,	PUNCT
cet-14807	107	63	r.	r.	PROPN
cet-14807	107	64	,	,	PUNCT
cet-14807	107	65	yanuar	yanuar	NOUN
cet-14807	107	66	,	,	PUNCT
cet-14807	107	67	a.	a.	NOUN
cet-14807	107	68	,	,	PUNCT
cet-14807	107	69	2022	2022	NUM
cet-14807	107	70	,	,	PUNCT
cet-14807	107	71	computational	computational	ADJ
cet-14807	107	72	studies	study	NOUN
cet-14807	107	73	of	of	ADP
cet-14807	107	74	thiourea	thiourea	NOUN
cet-14807	107	75	derivatives	derivative	NOUN
cet-14807	107	76	as	as	ADP
cet-14807	107	77	anticancer	anticancer	NOUN
cet-14807	107	78	candidates	candidate	NOUN
cet-14807	107	79	through	through	ADP
cet-14807	107	80	inhibition	inhibition	NOUN
cet-14807	107	81	of	of	ADP
cet-14807	107	82	sirtuin-1	sirtuin-1	NOUN
cet-14807	107	83	(	(	PUNCT
cet-14807	107	84	sirt1	sirt1	NOUN
cet-14807	107	85	)	)	PUNCT
cet-14807	107	86	,	,	PUNCT
cet-14807	107	87	jurnal	jurnal	ADJ
cet-14807	107	88	kimia	kimia	NOUN
cet-14807	107	89	sains	sains	PROPN
cet-14807	107	90	dan	dan	PROPN
cet-14807	107	91	aplikasi	aplikasi	PROPN
cet-14807	107	92	,	,	PUNCT
cet-14807	107	93	25(3	25(3	NUM
cet-14807	107	94	)	)	PUNCT
cet-14807	107	95	,	,	PUNCT
cet-14807	107	96	87	87	NUM
cet-14807	107	97	-	-	SYM
cet-14807	107	98	96	96	NUM
cet-14807	107	99	.	.	PUNCT
cet-14807	108	1	shah	shah	NOUN
cet-14807	108	2	,	,	PUNCT
cet-14807	108	3	a.	a.	NOUN
cet-14807	108	4	p.	p.	PROPN
cet-14807	108	5	,	,	PUNCT
cet-14807	108	6	parmar	parmar	PROPN
cet-14807	108	7	,	,	PUNCT
cet-14807	108	8	g.	g.	PROPN
cet-14807	108	9	r.	r.	PROPN
cet-14807	108	10	,	,	PUNCT
cet-14807	108	11	sailor	sailor	NOUN
cet-14807	108	12	,	,	PUNCT
cet-14807	108	13	g.	g.	PROPN
cet-14807	108	14	u.	u.	PROPN
cet-14807	108	15	,	,	PUNCT
cet-14807	108	16	seth	seth	PROPN
cet-14807	108	17	,	,	PUNCT
cet-14807	108	18	a.	a.	PROPN
cet-14807	108	19	k.	k.	PROPN
cet-14807	108	20	,	,	PUNCT
cet-14807	108	21	2019	2019	NUM
cet-14807	108	22	,	,	PUNCT
cet-14807	108	23	antimalarial	antimalarial	ADJ
cet-14807	108	24	phytochemicals	phytochemical	NOUN
cet-14807	108	25	identification	identification	NOUN
cet-14807	108	26	from	from	ADP
cet-14807	108	27	euphorbia	euphorbia	ADJ
cet-14807	108	28	hirta	hirta	PROPN
cet-14807	108	29	against	against	ADP
cet-14807	108	30	plasmepsin	plasmepsin	NOUN
cet-14807	108	31	protease	protease	NOUN
cet-14807	108	32	:	:	PUNCT
cet-14807	108	33	an	an	DET
cet-14807	108	34	in	in	ADP
cet-14807	108	35	-	-	PUNCT
cet-14807	108	36	silico	silico	NOUN
cet-14807	108	37	approach	approach	NOUN
cet-14807	108	38	,	,	PUNCT
cet-14807	108	39	folia	folia	PROPN
cet-14807	108	40	medica	medica	PROPN
cet-14807	108	41	,	,	PUNCT
cet-14807	108	42	61(4	61(4	NUM
cet-14807	108	43	)	)	PUNCT
cet-14807	108	44	,	,	PUNCT
cet-14807	108	45	584–593	584–593	NUM
cet-14807	108	46	.	.	PUNCT
cet-14807	109	1	sukmanadi	sukmanadi	PROPN
cet-14807	109	2	,	,	PUNCT
cet-14807	109	3	m.	m.	NOUN
cet-14807	109	4	,	,	PUNCT
cet-14807	109	5	effendi	effendi	X
cet-14807	109	6	,	,	PUNCT
cet-14807	109	7	m.	m.	NOUN
cet-14807	109	8	h.	h.	PROPN
cet-14807	109	9	,	,	PUNCT
cet-14807	109	10	2021	2021	NUM
cet-14807	109	11	,	,	PUNCT
cet-14807	109	12	the	the	DET
cet-14807	109	13	protective	protective	ADJ
cet-14807	109	14	effect	effect	NOUN
cet-14807	109	15	of	of	ADP
cet-14807	109	16	capsaicin	capsaicin	PROPN
cet-14807	109	17	(	(	PUNCT
cet-14807	109	18	capsicum	capsicum	NOUN
cet-14807	109	19	annum	annum	X
cet-14807	109	20	l	l	NOUN
cet-14807	109	21	)	)	PUNCT
cet-14807	109	22	against	against	ADP
cet-14807	109	23	the	the	DET
cet-14807	109	24	induction	induction	NOUN
cet-14807	109	25	of	of	ADP
cet-14807	109	26	aflatoxin	aflatoxin	NOUN
cet-14807	109	27	b1	b1	NOUN
cet-14807	109	28	in	in	ADP
cet-14807	109	29	hepatocytes	hepatocyte	NOUN
cet-14807	109	30	:	:	PUNCT
cet-14807	109	31	a	a	DET
cet-14807	109	32	study	study	NOUN
cet-14807	109	33	of	of	ADP
cet-14807	109	34	liver	liver	NOUN
cet-14807	109	35	histopathology	histopathology	NOUN
cet-14807	109	36	in	in	ADP
cet-14807	109	37	mice	mouse	NOUN
cet-14807	109	38	(	(	PUNCT
cet-14807	109	39	mus	mus	PROPN
cet-14807	109	40	musculus	musculus	PROPN
cet-14807	109	41	)	)	PUNCT
cet-14807	109	42	,	,	PUNCT
cet-14807	109	43	research	research	NOUN
cet-14807	109	44	journal	journal	NOUN
cet-14807	109	45	of	of	ADP
cet-14807	109	46	pharmacy	pharmacy	NOUN
cet-14807	109	47	and	and	CCONJ
cet-14807	109	48	technology	technology	NOUN
cet-14807	109	49	,	,	PUNCT
cet-14807	109	50	14(2	14(2	NUM
cet-14807	109	51	)	)	PUNCT
cet-14807	109	52	,	,	PUNCT
cet-14807	109	53	813–816	813–816	NUM
cet-14807	109	54	.	.	PUNCT
cet-14807	110	1	sunani	sunani	PROPN
cet-14807	110	2	,	,	PUNCT
cet-14807	110	3	s.	s.	PROPN
cet-14807	110	4	,	,	PUNCT
cet-14807	110	5	andani	andani	ADJ
cet-14807	110	6	,	,	PUNCT
cet-14807	110	7	m.	m.	NOUN
cet-14807	110	8	,	,	PUNCT
cet-14807	110	9	kamaludin	kamaludin	PROPN
cet-14807	110	10	,	,	PUNCT
cet-14807	110	11	a.	a.	PROPN
cet-14807	110	12	m.	m.	PROPN
cet-14807	110	13	r.	r.	PROPN
cet-14807	110	14	,	,	PUNCT
cet-14807	110	15	helmi	helmi	PROPN
cet-14807	110	16	,	,	PUNCT
cet-14807	111	1	n.	n.	PROPN
cet-14807	111	2	a.	a.	PROPN
cet-14807	111	3	s.	s.	PROPN
cet-14807	111	4	s.	s.	PROPN
cet-14807	111	5	p.	p.	PROPN
cet-14807	111	6	,	,	PUNCT
cet-14807	111	7	mei	mei	PROPN
cet-14807	111	8	,	,	PUNCT
cet-14807	111	9	k.	k.	PROPN
cet-14807	111	10	k.	k.	PROPN
cet-14807	111	11	,	,	PUNCT
cet-14807	111	12	guspira	guspira	PROPN
cet-14807	111	13	,	,	PUNCT
cet-14807	111	14	y.	y.	PROPN
cet-14807	111	15	,	,	PUNCT
cet-14807	111	16	sabetta	sabetta	NOUN
cet-14807	111	17	,	,	PUNCT
cet-14807	111	18	o.	o.	PROPN
cet-14807	111	19	,	,	PUNCT
cet-14807	111	20	aulifa	aulifa	PROPN
cet-14807	111	21	,	,	PUNCT
cet-14807	111	22	d.	d.	PROPN
cet-14807	111	23	l.	l.	PROPN
cet-14807	111	24	,	,	PUNCT
cet-14807	111	25	2022	2022	NUM
cet-14807	111	26	,	,	PUNCT
cet-14807	111	27	in	in	ADP
cet-14807	111	28	silico	silico	NOUN
cet-14807	111	29	study	study	NOUN
cet-14807	111	30	of	of	ADP
cet-14807	111	31	compounds	compound	NOUN
cet-14807	111	32	in	in	ADP
cet-14807	111	33	bawang	bawang	PROPN
cet-14807	111	34	dayak	dayak	PROPN
cet-14807	111	35	(	(	PUNCT
cet-14807	111	36	eleutherine	eleutherine	PROPN
cet-14807	111	37	palmifolia	palmifolia	PROPN
cet-14807	111	38	(	(	PUNCT
cet-14807	111	39	l	l	NOUN
cet-14807	111	40	)	)	PUNCT
cet-14807	111	41	merr	merr	PROPN
cet-14807	111	42	.	.	PUNCT
cet-14807	111	43	)	)	PUNCT
cet-14807	112	1	bulbs	bulb	NOUN
cet-14807	112	2	on	on	ADP
cet-14807	112	3	alpha	alpha	ADJ
cet-14807	112	4	estrogen	estrogen	NOUN
cet-14807	112	5	receptors	receptor	NOUN
cet-14807	112	6	,	,	PUNCT
cet-14807	112	7	iscc	iscc	PROPN
cet-14807	112	8	(	(	PUNCT
cet-14807	112	9	indonesian	indonesian	PROPN
cet-14807	112	10	journal	journal	PROPN
cet-14807	112	11	of	of	ADP
cet-14807	112	12	cancer	cancer	NOUN
cet-14807	112	13	chemoprevention	chemoprevention	PROPN
cet-14807	112	14	)	)	PUNCT
cet-14807	112	15	,	,	PUNCT
cet-14807	112	16	13(2	13(2	NOUN
cet-14807	112	17	)	)	PUNCT
cet-14807	112	18	,	,	PUNCT
cet-14807	112	19	83	83	NUM
cet-14807	112	20	.	.	PUNCT
cet-14807	113	1	syahputra	syahputra	PROPN
cet-14807	113	2	,	,	PUNCT
cet-14807	113	3	g	g	PROPN
cet-14807	113	4	,	,	PUNCT
cet-14807	113	5	gustini	gustini	NOUN
cet-14807	113	6	n	n	NOUN
cet-14807	113	7	,	,	PUNCT
cet-14807	113	8	bustanussalam	bustanussalam	PROPN
cet-14807	113	9	b	b	PROPN
cet-14807	113	10	,	,	PUNCT
cet-14807	113	11	hapsari	hapsari	PROPN
cet-14807	113	12	y	y	PROPN
cet-14807	113	13	,	,	PUNCT
cet-14807	113	14	sari	sari	PROPN
cet-14807	113	15	m	m	PROPN
cet-14807	113	16	,	,	PUNCT
cet-14807	113	17	ardiansyah	ardiansyah	ADP
cet-14807	113	18	a	a	PRON
cet-14807	113	19	,	,	PUNCT
cet-14807	113	20	bayu	bayu	VERB
cet-14807	113	21	a	a	PRON
cet-14807	113	22	,	,	PUNCT
cet-14807	113	23	putra	putra	PROPN
cet-14807	113	24	my	my	PRON
cet-14807	113	25	.	.	PROPN
cet-14807	113	26	,	,	PUNCT
cet-14807	113	27	2021	2021	NUM
cet-14807	113	28	,	,	PUNCT
cet-14807	113	29	molecular	molecular	ADJ
cet-14807	113	30	docking	docking	NOUN
cet-14807	113	31	of	of	ADP
cet-14807	113	32	secondary	secondary	ADJ
cet-14807	113	33	metabolites	metabolite	NOUN
cet-14807	113	34	from	from	ADP
cet-14807	113	35	indonesian	indonesian	ADJ
cet-14807	113	36	marine	marine	PROPN
cet-14807	113	37	and	and	CCONJ
cet-14807	113	38	terrestrial	terrestrial	ADJ
cet-14807	113	39	organisms	organism	NOUN
cet-14807	113	40	targeting	target	VERB
cet-14807	113	41	sars	sar	NOUN
cet-14807	113	42	-	-	PUNCT
cet-14807	113	43	cov-2	cov-2	NOUN
cet-14807	113	44	ace-2	ace-2	ADJ
cet-14807	113	45	,	,	PUNCT
cet-14807	113	46	m	m	VERB
cet-14807	113	47	pro	pro	ADJ
cet-14807	113	48	,	,	PUNCT
cet-14807	113	49	and	and	CCONJ
cet-14807	113	50	pl	pl	X
cet-14807	113	51	pro	pro	ADJ
cet-14807	113	52	receptors	receptor	NOUN
cet-14807	113	53	,	,	PUNCT
cet-14807	113	54	pharmacia	pharmacia	PROPN
cet-14807	113	55	,	,	PUNCT
cet-14807	113	56	68(3	68(3	PROPN
cet-14807	113	57	)	)	PUNCT
cet-14807	113	58	,	,	PUNCT
cet-14807	113	59	533	533	NUM
cet-14807	113	60	-	-	SYM
cet-14807	113	61	560	560	NUM
cet-14807	113	62	.	.	PUNCT
cet-14807	114	1	trott	trott	PROPN
cet-14807	114	2	,	,	PUNCT
cet-14807	114	3	o.	o.	PROPN
cet-14807	114	4	,	,	PUNCT
cet-14807	114	5	olson	olson	PROPN
cet-14807	114	6	,	,	PUNCT
cet-14807	114	7	a.	a.	PROPN
cet-14807	114	8	j.	j.	PROPN
cet-14807	114	9	,	,	PUNCT
cet-14807	114	10	2010	2010	NUM
cet-14807	114	11	,	,	PUNCT
cet-14807	114	12	autodock	autodock	NOUN
cet-14807	114	13	vina	vina	NOUN
cet-14807	114	14	:	:	PUNCT
cet-14807	114	15	improving	improve	VERB
cet-14807	114	16	the	the	DET
cet-14807	114	17	speed	speed	NOUN
cet-14807	114	18	and	and	CCONJ
cet-14807	114	19	accuracy	accuracy	NOUN
cet-14807	114	20	of	of	ADP
cet-14807	114	21	docking	docking	NOUN
cet-14807	114	22	with	with	ADP
cet-14807	114	23	a	a	DET
cet-14807	114	24	new	new	ADJ
cet-14807	114	25	scoring	scoring	NOUN
cet-14807	114	26	function	function	NOUN
cet-14807	114	27	,	,	PUNCT
cet-14807	114	28	efficient	efficient	ADJ
cet-14807	114	29	optimization	optimization	NOUN
cet-14807	114	30	,	,	PUNCT
cet-14807	114	31	and	and	CCONJ
cet-14807	114	32	multithreading	multithreade	VERB
cet-14807	114	33	,	,	PUNCT
cet-14807	114	34	journal	journal	NOUN
cet-14807	114	35	of	of	ADP
cet-14807	114	36	computational	computational	ADJ
cet-14807	114	37	chemistry	chemistry	NOUN
cet-14807	114	38	,	,	PUNCT
cet-14807	114	39	31(2	31(2	NUM
cet-14807	114	40	)	)	PUNCT
cet-14807	114	41	,	,	PUNCT
cet-14807	114	42	455–461	455–461	NUM
cet-14807	114	43	.	.	PUNCT
cet-14807	115	1	undurraga	undurraga	PROPN
cet-14807	115	2	,	,	PUNCT
cet-14807	115	3	e.	e.	PROPN
cet-14807	115	4	a.	a.	PROPN
cet-14807	115	5	,	,	PUNCT
cet-14807	115	6	edillo	edillo	PROPN
cet-14807	115	7	,	,	PUNCT
cet-14807	115	8	f.	f.	PROPN
cet-14807	115	9	e.	e.	PROPN
cet-14807	115	10	,	,	PUNCT
cet-14807	115	11	erasmo	erasmo	PROPN
cet-14807	115	12	,	,	PUNCT
cet-14807	115	13	j.	j.	PROPN
cet-14807	115	14	n.	n.	PROPN
cet-14807	115	15	v.	v.	PROPN
cet-14807	115	16	,	,	PUNCT
cet-14807	115	17	alera	alera	NOUN
cet-14807	115	18	,	,	PUNCT
cet-14807	115	19	m.	m.	NOUN
cet-14807	115	20	t.	t.	PROPN
cet-14807	115	21	p.	p.	PROPN
cet-14807	115	22	,	,	PUNCT
cet-14807	115	23	yoon	yoon	PROPN
cet-14807	115	24	,	,	PUNCT
cet-14807	115	25	i.	i.	PROPN
cet-14807	115	26	k.	k.	PROPN
cet-14807	115	27	,	,	PUNCT
cet-14807	115	28	largo	largo	PROPN
cet-14807	115	29	,	,	PUNCT
cet-14807	115	30	f.	f.	PROPN
cet-14807	115	31	m.	m.	PROPN
cet-14807	115	32	,	,	PUNCT
cet-14807	115	33	shepard	shepard	NOUN
cet-14807	115	34	,	,	PUNCT
cet-14807	115	35	d.	d.	PROPN
cet-14807	115	36	s.	s.	PROPN
cet-14807	115	37	,	,	PUNCT
cet-14807	115	38	2017	2017	NUM
cet-14807	115	39	,	,	PUNCT
cet-14807	115	40	disease	disease	NOUN
cet-14807	115	41	burden	burden	NOUN
cet-14807	115	42	of	of	ADP
cet-14807	115	43	dengue	dengue	NOUN
cet-14807	115	44	in	in	ADP
cet-14807	115	45	the	the	DET
cet-14807	115	46	philippines	philippine	NOUN
cet-14807	115	47	:	:	PUNCT
cet-14807	115	48	adjusting	adjust	VERB
cet-14807	115	49	for	for	ADP
cet-14807	115	50	underreporting	underreporte	VERB
cet-14807	115	51	by	by	ADP
cet-14807	115	52	comparing	compare	VERB
cet-14807	115	53	active	active	ADJ
cet-14807	115	54	and	and	CCONJ
cet-14807	115	55	passive	passive	ADJ
cet-14807	115	56	dengue	dengue	NOUN
cet-14807	115	57	surveillance	surveillance	NOUN
cet-14807	115	58	in	in	ADP
cet-14807	115	59	punta	punta	PROPN
cet-14807	115	60	princesa	princesa	PROPN
cet-14807	115	61	,	,	PUNCT
cet-14807	115	62	cebu	cebu	NOUN
cet-14807	115	63	city	city	NOUN
cet-14807	115	64	,	,	PUNCT
cet-14807	115	65	the	the	DET
cet-14807	115	66	american	american	ADJ
cet-14807	115	67	journal	journal	PROPN
cet-14807	115	68	of	of	ADP
cet-14807	115	69	tropical	tropical	ADJ
cet-14807	115	70	medicine	medicine	NOUN
cet-14807	115	71	and	and	CCONJ
cet-14807	115	72	hygiene	hygiene	NOUN
cet-14807	115	73	,	,	PUNCT
cet-14807	115	74	96(4	96(4	NOUN
cet-14807	115	75	)	)	PUNCT
cet-14807	115	76	,	,	PUNCT
cet-14807	115	77	887–898	887–898	NUM
cet-14807	115	78	.	.	PUNCT
cet-14807	116	1	walters	walters	PROPN
cet-14807	116	2	,	,	PUNCT
cet-14807	116	3	w	w	PROPN
cet-14807	116	4	p.	p.	PROPN
cet-14807	116	5	,	,	PUNCT
cet-14807	116	6	2012	2012	NUM
cet-14807	116	7	,	,	PUNCT
cet-14807	116	8	going	go	VERB
cet-14807	116	9	further	far	ADV
cet-14807	116	10	than	than	ADP
cet-14807	116	11	lipinski	lipinski	PROPN
cet-14807	116	12	's	's	PART
cet-14807	116	13	rule	rule	NOUN
cet-14807	116	14	in	in	ADP
cet-14807	116	15	drug	drug	NOUN
cet-14807	116	16	design	design	NOUN
cet-14807	116	17	.	.	PUNCT
cet-14807	117	1	expert	expert	ADJ
cet-14807	117	2	opinion	opinion	NOUN
cet-14807	117	3	on	on	ADP
cet-14807	117	4	drug	drug	NOUN
cet-14807	117	5	discovery	discovery	NOUN
cet-14807	117	6	,	,	PUNCT
cet-14807	117	7	7(2	7(2	NUM
cet-14807	117	8	)	)	PUNCT
cet-14807	117	9	,	,	PUNCT
cet-14807	117	10	99	99	NUM
cet-14807	117	11	-	-	SYM
cet-14807	117	12	107	107	NUM
cet-14807	117	13	.	.	PUNCT
cet-14807	118	1	world	world	PROPN
cet-14807	118	2	health	health	PROPN
cet-14807	118	3	organization	organization	PROPN
cet-14807	118	4	.	.	PUNCT
cet-14807	119	1	regional	regional	ADJ
cet-14807	119	2	office	office	NOUN
cet-14807	119	3	for	for	ADP
cet-14807	119	4	the	the	DET
cet-14807	119	5	western	western	ADJ
cet-14807	119	6	pacific	pacific	PROPN
cet-14807	119	7	.	.	PUNCT
cet-14807	120	1	2022	2022	NUM
cet-14807	120	2	.	.	PUNCT
cet-14807	121	1	dengue	dengue	NOUN
cet-14807	121	2	situation	situation	NOUN
cet-14807	121	3	updates	update	VERB
cet-14807	121	4	2022	2022	NUM
cet-14807	121	5	.	.	PUNCT
cet-14807	122	1	who	who	PRON
cet-14807	122	2	regional	regional	ADJ
cet-14807	122	3	office	office	NOUN
cet-14807	122	4	for	for	ADP
cet-14807	122	5	the	the	DET
cet-14807	122	6	western	western	ADJ
cet-14807	122	7	pacific	pacific	PROPN
cet-14807	122	8	<	<	X
cet-14807	122	9	https://iris.who.int/bitstream/handle/10665/352792/dengue20220908.pdf	https://iris.who.int/bitstream/handle/10665/352792/dengue20220908.pdf	X
cet-14807	122	10	>	>	X
cet-14807	122	11	accessed	access	VERB
cet-14807	122	12	19.06.2024	19.06.2024	PROPN
cet-14807	122	13	.	.	PROPN
cet-14807	122	14	72	72	NUM
cet-14807	122	15	012.pdf	012.pdf	NUM
cet-14807	122	16	molecular	molecular	ADJ
cet-14807	122	17	docking	docking	NOUN
cet-14807	122	18	of	of	ADP
cet-14807	122	19	bioactive	bioactive	ADJ
cet-14807	122	20	components	component	NOUN
cet-14807	122	21	of	of	ADP
cet-14807	122	22	tawa	tawa	PROPN
cet-14807	122	23	-	-	PUNCT
cet-14807	122	24	tawa	tawa	PROPN
cet-14807	122	25	(	(	PUNCT
cet-14807	122	26	euphorbia	euphorbia	PROPN
cet-14807	122	27	hirta	hirta	PROPN
cet-14807	122	28	l.	l.	PROPN
cet-14807	122	29	)	)	PUNCT
cet-14807	122	30	leaves	leave	VERB
cet-14807	122	31	as	as	ADP
cet-14807	122	32	inhibitor	inhibitor	NOUN
cet-14807	122	33	against	against	ADP
cet-14807	122	34	the	the	DET
cet-14807	122	35	ns2b	ns2b	NOUN
cet-14807	122	36	-	-	PUNCT
cet-14807	122	37	ns3	ns3	NOUN
cet-14807	122	38	protease	protease	NOUN
cet-14807	122	39	of	of	ADP
cet-14807	122	40	denv-2	denv-2	NUM