id	sid	tid	token	lemma	pos
cet-15445	1	1	doi	doi	NOUN
cet-15445	1	2	:	:	PUNCT
cet-15445	1	3	10.3303	10.3303	NUM
cet-15445	1	4	/	/	SYM
cet-15445	1	5	cet25117195	cet25117195	NOUN
cet-15445	1	6	paper	paper	NOUN
cet-15445	1	7	received	receive	VERB
cet-15445	1	8	:	:	PUNCT
cet-15445	1	9	11	11	NUM
cet-15445	1	10	january	january	NOUN
cet-15445	1	11	2025	2025	NUM
cet-15445	1	12	;	;	PUNCT
cet-15445	1	13	revised	revise	VERB
cet-15445	1	14	:	:	PUNCT
cet-15445	1	15	18	18	NUM
cet-15445	1	16	march	march	NOUN
cet-15445	1	17	2025	2025	NUM
cet-15445	1	18	;	;	PUNCT
cet-15445	1	19	accepted	accept	VERB
cet-15445	1	20	:	:	PUNCT
cet-15445	1	21	26	26	NUM
cet-15445	1	22	may	may	AUX
cet-15445	1	23	2025	2025	NUM
cet-15445	1	24	please	please	INTJ
cet-15445	1	25	cite	cite	VERB
cet-15445	1	26	this	this	DET
cet-15445	1	27	article	article	NOUN
cet-15445	1	28	as	as	ADP
cet-15445	1	29	:	:	PUNCT
cet-15445	1	30	sofia	sofia	PROPN
cet-15445	1	31	d.	d.	PROPN
cet-15445	1	32	,	,	PUNCT
cet-15445	1	33	moffa	moffa	NOUN
cet-15445	1	34	m.	m.	NOUN
cet-15445	1	35	,	,	PUNCT
cet-15445	1	36	trucillo	trucillo	PROPN
cet-15445	1	37	p.	p.	PROPN
cet-15445	1	38	,	,	PUNCT
cet-15445	1	39	2025	2025	NUM
cet-15445	1	40	,	,	PUNCT
cet-15445	1	41	innovative	innovative	ADJ
cet-15445	1	42	supercritical	supercritical	ADJ
cet-15445	1	43	particle	particle	NOUN
cet-15445	1	44	formation	formation	NOUN
cet-15445	1	45	for	for	ADP
cet-15445	1	46	the	the	DET
cet-15445	1	47	sustainable	sustainable	ADJ
cet-15445	1	48	manufacturing	manufacturing	NOUN
cet-15445	1	49	of	of	ADP
cet-15445	1	50	advanced	advanced	ADJ
cet-15445	1	51	drug	drug	NOUN
cet-15445	1	52	delivery	delivery	NOUN
cet-15445	1	53	systems	system	NOUN
cet-15445	1	54	,	,	PUNCT
cet-15445	1	55	chemical	chemical	NOUN
cet-15445	1	56	engineering	engineering	NOUN
cet-15445	1	57	transactions	transaction	NOUN
cet-15445	1	58	,	,	PUNCT
cet-15445	1	59	117	117	NUM
cet-15445	1	60	,	,	PUNCT
cet-15445	1	61	1165	1165	NUM
cet-15445	1	62	-	-	SYM
cet-15445	1	63	1170	1170	NUM
cet-15445	1	64	doi:10.3303	doi:10.3303	NOUN
cet-15445	1	65	/	/	SYM
cet-15445	1	66	cet25117195	cet25117195	NOUN
cet-15445	1	67	chemical	chemical	NOUN
cet-15445	1	68	engineering	engineering	NOUN
cet-15445	1	69	transactions	transaction	NOUN
cet-15445	1	70	vol	vol	NOUN
cet-15445	1	71	.	.	PROPN
cet-15445	1	72	117	117	NUM
cet-15445	1	73	,	,	PUNCT
cet-15445	1	74	2025	2025	NUM
cet-15445	1	75	a	a	DET
cet-15445	1	76	publication	publication	NOUN
cet-15445	1	77	of	of	ADP
cet-15445	1	78	the	the	DET
cet-15445	1	79	italian	italian	ADJ
cet-15445	1	80	association	association	NOUN
cet-15445	1	81	of	of	ADP
cet-15445	1	82	chemical	chemical	PROPN
cet-15445	1	83	engineering	engineering	NOUN
cet-15445	1	84	online	online	ADV
cet-15445	1	85	at	at	ADP
cet-15445	1	86	www.cetjournal.it	www.cetjournal.it	PROPN
cet-15445	1	87	guest	guest	NOUN
cet-15445	1	88	editors	editor	NOUN
cet-15445	1	89	:	:	PUNCT
cet-15445	1	90	fabrizio	fabrizio	PROPN
cet-15445	1	91	bezzo	bezzo	PROPN
cet-15445	1	92	,	,	PUNCT
cet-15445	1	93	flavio	flavio	PROPN
cet-15445	1	94	manenti	manenti	PROPN
cet-15445	1	95	,	,	PUNCT
cet-15445	1	96	gabriele	gabriele	PROPN
cet-15445	1	97	pannocchia	pannocchia	PROPN
cet-15445	1	98	,	,	PUNCT
cet-15445	1	99	almerinda	almerinda	PROPN
cet-15445	1	100	di	di	PROPN
cet-15445	1	101	benedetto	benedetto	PROPN
cet-15445	1	102	copyright	copyright	PROPN
cet-15445	1	103	©	©	PROPN
cet-15445	1	104	2025	2025	NUM
cet-15445	1	105	,	,	PUNCT
cet-15445	1	106	aidic	aidic	ADJ
cet-15445	1	107	servizi	servizi	PROPN
cet-15445	1	108	s.r.l	s.r.l	NOUN
cet-15445	1	109	.	.	PUNCT
cet-15445	2	1	isbn	isbn	PROPN
cet-15445	2	2	979	979	NUM
cet-15445	2	3	-	-	SYM
cet-15445	2	4	12	12	NUM
cet-15445	2	5	-	-	PUNCT
cet-15445	2	6	81206	81206	NUM
cet-15445	2	7	-	-	SYM
cet-15445	2	8	17	17	NUM
cet-15445	2	9	-	-	SYM
cet-15445	2	10	5	5	NUM
cet-15445	2	11	;	;	PUNCT
cet-15445	2	12	issn	issn	PROPN
cet-15445	2	13	2283	2283	NUM
cet-15445	2	14	-	-	SYM
cet-15445	2	15	9216	9216	NUM
cet-15445	2	16	innovative	innovative	ADJ
cet-15445	2	17	supercritical	supercritical	ADJ
cet-15445	2	18	particle	particle	NOUN
cet-15445	2	19	formation	formation	NOUN
cet-15445	2	20	for	for	ADP
cet-15445	2	21	the	the	DET
cet-15445	2	22	sustainable	sustainable	ADJ
cet-15445	2	23	manufacturing	manufacturing	NOUN
cet-15445	2	24	of	of	ADP
cet-15445	2	25	advanced	advanced	ADJ
cet-15445	2	26	drug	drug	NOUN
cet-15445	2	27	delivery	delivery	NOUN
cet-15445	2	28	systems	system	NOUN
cet-15445	2	29	daniele	daniele	PROPN
cet-15445	2	30	sofia	sofia	PROPN
cet-15445	2	31	a	a	PRON
cet-15445	2	32	,	,	PUNCT
cet-15445	2	33	c	c	PROPN
cet-15445	2	34	,	,	PUNCT
cet-15445	2	35	massimo	massimo	PROPN
cet-15445	2	36	moffa	moffa	PROPN
cet-15445	2	37	a	a	PROPN
cet-15445	2	38	,	,	PUNCT
cet-15445	2	39	paolo	paolo	PROPN
cet-15445	2	40	trucillo	trucillo	PROPN
cet-15445	2	41	a	a	DET
cet-15445	2	42	,	,	PUNCT
cet-15445	2	43	b	b	NOUN
cet-15445	2	44	,	,	PUNCT
cet-15445	2	45	*	*	ADJ
cet-15445	2	46	aiodo	aiodo	NOUN
cet-15445	2	47	,	,	PUNCT
cet-15445	2	48	corso	corso	PROPN
cet-15445	2	49	vittorio	vittorio	PROPN
cet-15445	2	50	emanuele	emanuele	PROPN
cet-15445	2	51	,	,	PUNCT
cet-15445	2	52	143	143	NUM
cet-15445	2	53	–	–	SYM
cet-15445	2	54	84123	84123	NUM
cet-15445	2	55	salerno	salerno	NOUN
cet-15445	2	56	,	,	PUNCT
cet-15445	2	57	italy	italy	PROPN
cet-15445	2	58	bdipartimento	bdipartimento	ADP
cet-15445	2	59	di	di	PROPN
cet-15445	2	60	ingegneria	ingegneria	PROPN
cet-15445	2	61	chimica	chimica	PROPN
cet-15445	2	62	,	,	PUNCT
cet-15445	2	63	dei	dei	NOUN
cet-15445	2	64	materiali	materiali	PROPN
cet-15445	2	65	e	e	PROPN
cet-15445	2	66	della	della	PROPN
cet-15445	2	67	produzione	produzione	X
cet-15445	2	68	industriale	industriale	PROPN
cet-15445	2	69	,	,	PUNCT
cet-15445	2	70	university	university	PROPN
cet-15445	2	71	of	of	ADP
cet-15445	2	72	naples	naples	PROPN
cet-15445	2	73	federico	federico	PROPN
cet-15445	2	74	ii	ii	PROPN
cet-15445	2	75	,	,	PUNCT
cet-15445	2	76	p.le	p.le	PROPN
cet-15445	2	77	v.	v.	ADP
cet-15445	2	78	tecchio	tecchio	PROPN
cet-15445	2	79	,	,	PUNCT
cet-15445	2	80	80	80	NUM
cet-15445	2	81	,	,	PUNCT
cet-15445	2	82	80125	80125	NUM
cet-15445	2	83	,	,	PUNCT
cet-15445	2	84	napoli	napoli	PROPN
cet-15445	2	85	,	,	PUNCT
cet-15445	2	86	italy	italy	PROPN
cet-15445	2	87	cdepartment	cdepartment	NOUN
cet-15445	2	88	of	of	ADP
cet-15445	2	89	computer	computer	NOUN
cet-15445	2	90	engineering	engineering	NOUN
cet-15445	2	91	,	,	PUNCT
cet-15445	2	92	modeling	modeling	NOUN
cet-15445	2	93	,	,	PUNCT
cet-15445	2	94	electronics	electronic	NOUN
cet-15445	2	95	and	and	CCONJ
cet-15445	2	96	systems	system	NOUN
cet-15445	2	97	,	,	PUNCT
cet-15445	2	98	university	university	NOUN
cet-15445	2	99	of	of	ADP
cet-15445	2	100	calabria	calabria	PROPN
cet-15445	2	101	,	,	PUNCT
cet-15445	2	102	via	via	ADP
cet-15445	2	103	p.	p.	PROPN
cet-15445	2	104	bucci	bucci	PROPN
cet-15445	2	105	cubo	cubo	VERB
cet-15445	2	106	44	44	NUM
cet-15445	2	107	/	/	SYM
cet-15445	2	108	a	a	DET
cet-15445	2	109	rende	rende	X
cet-15445	2	110	(	(	PUNCT
cet-15445	2	111	cs	cs	PROPN
cet-15445	2	112	)	)	PUNCT
cet-15445	2	113	,	,	PUNCT
cet-15445	2	114	87036	87036	NUM
cet-15445	2	115	,	,	PUNCT
cet-15445	2	116	italy	italy	PROPN
cet-15445	2	117	paolo.trucillo@unina.it	paolo.trucillo@unina.it	VERB
cet-15445	2	118	the	the	DET
cet-15445	2	119	supercritical	supercritical	ADJ
cet-15445	2	120	particle	particle	NOUN
cet-15445	2	121	formation	formation	NOUN
cet-15445	2	122	(	(	PUNCT
cet-15445	2	123	spaf	spaf	NOUN
cet-15445	2	124	)	)	PUNCT
cet-15445	2	125	process	process	NOUN
cet-15445	2	126	represents	represent	VERB
cet-15445	2	127	a	a	DET
cet-15445	2	128	significant	significant	ADJ
cet-15445	2	129	advancement	advancement	NOUN
cet-15445	2	130	in	in	ADP
cet-15445	2	131	the	the	DET
cet-15445	2	132	development	development	NOUN
cet-15445	2	133	of	of	ADP
cet-15445	2	134	drug	drug	NOUN
cet-15445	2	135	delivery	delivery	NOUN
cet-15445	2	136	systems	system	NOUN
cet-15445	2	137	for	for	ADP
cet-15445	2	138	both	both	DET
cet-15445	2	139	pharmaceutical	pharmaceutical	ADJ
cet-15445	2	140	and	and	CCONJ
cet-15445	2	141	nutraceutical	nutraceutical	ADJ
cet-15445	2	142	applications	application	NOUN
cet-15445	2	143	.	.	PUNCT
cet-15445	3	1	traditional	traditional	ADJ
cet-15445	3	2	manufacturing	manufacturing	NOUN
cet-15445	3	3	methods	method	NOUN
cet-15445	3	4	often	often	ADV
cet-15445	3	5	face	face	VERB
cet-15445	3	6	challenges	challenge	NOUN
cet-15445	3	7	such	such	ADJ
cet-15445	3	8	as	as	ADP
cet-15445	3	9	residual	residual	ADJ
cet-15445	3	10	solvent	solvent	NOUN
cet-15445	3	11	contamination	contamination	NOUN
cet-15445	3	12	,	,	PUNCT
cet-15445	3	13	low	low	ADJ
cet-15445	3	14	reproducibility	reproducibility	NOUN
cet-15445	3	15	,	,	PUNCT
cet-15445	3	16	and	and	CCONJ
cet-15445	3	17	limited	limited	ADJ
cet-15445	3	18	versatility	versatility	NOUN
cet-15445	3	19	in	in	ADP
cet-15445	3	20	bioactives	bioactive	NOUN
cet-15445	3	21	encapsulation	encapsulation	NOUN
cet-15445	3	22	.	.	PUNCT
cet-15445	4	1	on	on	ADP
cet-15445	4	2	the	the	DET
cet-15445	4	3	contrary	contrary	NOUN
cet-15445	4	4	,	,	PUNCT
cet-15445	4	5	spaf	spaf	PROPN
cet-15445	4	6	exploits	exploit	VERB
cet-15445	4	7	the	the	DET
cet-15445	4	8	benefits	benefit	NOUN
cet-15445	4	9	deriving	derive	VERB
cet-15445	4	10	from	from	ADP
cet-15445	4	11	the	the	DET
cet-15445	4	12	use	use	NOUN
cet-15445	4	13	of	of	ADP
cet-15445	4	14	supercritical	supercritical	ADJ
cet-15445	4	15	fluids	fluid	NOUN
cet-15445	4	16	to	to	PART
cet-15445	4	17	remove	remove	VERB
cet-15445	4	18	solvent	solvent	ADJ
cet-15445	4	19	residue	residue	NOUN
cet-15445	4	20	,	,	PUNCT
cet-15445	4	21	thus	thus	ADV
cet-15445	4	22	resulting	result	VERB
cet-15445	4	23	in	in	ADP
cet-15445	4	24	a	a	DET
cet-15445	4	25	highly	highly	ADV
cet-15445	4	26	efficient	efficient	ADJ
cet-15445	4	27	,	,	PUNCT
cet-15445	4	28	eco	eco	NOUN
cet-15445	4	29	-	-	PUNCT
cet-15445	4	30	friendly	friendly	ADJ
cet-15445	4	31	process	process	NOUN
cet-15445	4	32	,	,	PUNCT
cet-15445	4	33	guaranteeing	guarantee	VERB
cet-15445	4	34	the	the	DET
cet-15445	4	35	coupling	coupling	NOUN
cet-15445	4	36	of	of	ADP
cet-15445	4	37	several	several	ADJ
cet-15445	4	38	hydrophilic	hydrophilic	ADJ
cet-15445	4	39	and	and	CCONJ
cet-15445	4	40	lipophilic	lipophilic	ADJ
cet-15445	4	41	compounds	compound	NOUN
cet-15445	4	42	with	with	ADP
cet-15445	4	43	polymeric	polymeric	ADJ
cet-15445	4	44	or	or	CCONJ
cet-15445	4	45	lipidic	lipidic	ADJ
cet-15445	4	46	carriers	carrier	NOUN
cet-15445	4	47	.	.	PUNCT
cet-15445	5	1	this	this	DET
cet-15445	5	2	technique	technique	NOUN
cet-15445	5	3	improves	improve	VERB
cet-15445	5	4	the	the	DET
cet-15445	5	5	yield	yield	NOUN
cet-15445	5	6	at	at	ADP
cet-15445	5	7	industrial	industrial	ADJ
cet-15445	5	8	level	level	NOUN
cet-15445	5	9	,	,	PUNCT
cet-15445	5	10	without	without	ADP
cet-15445	5	11	losing	lose	VERB
cet-15445	5	12	control	control	NOUN
cet-15445	5	13	over	over	ADP
cet-15445	5	14	particle	particle	NOUN
cet-15445	5	15	size	size	NOUN
cet-15445	5	16	distribution	distribution	NOUN
cet-15445	5	17	and	and	CCONJ
cet-15445	5	18	morphology	morphology	NOUN
cet-15445	5	19	,	,	PUNCT
cet-15445	5	20	release	release	VERB
cet-15445	5	21	profile	profile	NOUN
cet-15445	5	22	and	and	CCONJ
cet-15445	5	23	cell	cell	NOUN
cet-15445	5	24	bioavailability	bioavailability	NOUN
cet-15445	5	25	of	of	ADP
cet-15445	5	26	active	active	ADJ
cet-15445	5	27	ingredients	ingredient	NOUN
cet-15445	5	28	.	.	PUNCT
cet-15445	6	1	the	the	DET
cet-15445	6	2	improved	improved	ADJ
cet-15445	6	3	stability	stability	NOUN
cet-15445	6	4	of	of	ADP
cet-15445	6	5	spaf	spaf	ADJ
cet-15445	6	6	products	product	NOUN
cet-15445	6	7	is	be	AUX
cet-15445	6	8	guaranteed	guarantee	VERB
cet-15445	6	9	by	by	ADP
cet-15445	6	10	the	the	DET
cet-15445	6	11	addition	addition	NOUN
cet-15445	6	12	of	of	ADP
cet-15445	6	13	a	a	DET
cet-15445	6	14	process	process	NOUN
cet-15445	6	15	unit	unit	NOUN
cet-15445	6	16	,	,	PUNCT
cet-15445	6	17	made	make	VERB
cet-15445	6	18	of	of	ADP
cet-15445	6	19	several	several	ADJ
cet-15445	6	20	freezedryers	freezedryer	NOUN
cet-15445	6	21	working	work	VERB
cet-15445	6	22	in	in	ADP
cet-15445	6	23	parallel	parallel	NOUN
cet-15445	6	24	,	,	PUNCT
cet-15445	6	25	to	to	PART
cet-15445	6	26	transform	transform	VERB
cet-15445	6	27	the	the	DET
cet-15445	6	28	liquid	liquid	ADJ
cet-15445	6	29	suspension	suspension	NOUN
cet-15445	6	30	of	of	ADP
cet-15445	6	31	carriers	carrier	NOUN
cet-15445	6	32	into	into	ADP
cet-15445	6	33	powder	powder	NOUN
cet-15445	6	34	stable	stable	ADJ
cet-15445	6	35	over	over	ADP
cet-15445	6	36	2	2	NUM
cet-15445	6	37	years	year	NOUN
cet-15445	6	38	.	.	PUNCT
cet-15445	7	1	the	the	DET
cet-15445	7	2	synergy	synergy	NOUN
cet-15445	7	3	between	between	ADP
cet-15445	7	4	supercritical	supercritical	ADJ
cet-15445	7	5	particle	particle	NOUN
cet-15445	7	6	formation	formation	NOUN
cet-15445	7	7	and	and	CCONJ
cet-15445	7	8	lyophilization	lyophilization	NOUN
cet-15445	7	9	offers	offer	VERB
cet-15445	7	10	a	a	DET
cet-15445	7	11	successful	successful	ADJ
cet-15445	7	12	platform	platform	NOUN
cet-15445	7	13	to	to	PART
cet-15445	7	14	produce	produce	VERB
cet-15445	7	15	highquality	highquality	NOUN
cet-15445	7	16	,	,	PUNCT
cet-15445	7	17	ready	ready	ADJ
cet-15445	7	18	-	-	PUNCT
cet-15445	7	19	to	to	ADP
cet-15445	7	20	-	-	PUNCT
cet-15445	7	21	market	market	NOUN
cet-15445	7	22	drug	drug	NOUN
cet-15445	7	23	delivery	delivery	NOUN
cet-15445	7	24	systems	system	NOUN
cet-15445	7	25	with	with	ADP
cet-15445	7	26	improved	improve	VERB
cet-15445	7	27	pharmacokinetic	pharmacokinetic	ADJ
cet-15445	7	28	properties	property	NOUN
cet-15445	7	29	.	.	PUNCT
cet-15445	8	1	this	this	DET
cet-15445	8	2	study	study	NOUN
cet-15445	8	3	highlights	highlight	NOUN
cet-15445	8	4	yield	yield	NOUN
cet-15445	8	5	,	,	PUNCT
cet-15445	8	6	profit	profit	NOUN
cet-15445	8	7	and	and	CCONJ
cet-15445	8	8	environmental	environmental	ADJ
cet-15445	8	9	benefits	benefit	NOUN
cet-15445	8	10	of	of	ADP
cet-15445	8	11	spaf	spaf	NOUN
cet-15445	8	12	,	,	PUNCT
cet-15445	8	13	positioning	position	VERB
cet-15445	8	14	it	it	PRON
cet-15445	8	15	as	as	ADP
cet-15445	8	16	a	a	DET
cet-15445	8	17	valid	valid	ADJ
cet-15445	8	18	alternative	alternative	NOUN
cet-15445	8	19	to	to	ADP
cet-15445	8	20	conventional	conventional	ADJ
cet-15445	8	21	production	production	NOUN
cet-15445	8	22	techniques	technique	NOUN
cet-15445	8	23	nowadays	nowadays	ADV
cet-15445	8	24	utilized	utilize	VERB
cet-15445	8	25	by	by	ADP
cet-15445	8	26	companies	company	NOUN
cet-15445	8	27	.	.	PUNCT
cet-15445	9	1	1	1	X
cet-15445	9	2	.	.	X
cet-15445	9	3	introduction	introduction	NOUN
cet-15445	9	4	the	the	DET
cet-15445	9	5	growing	grow	VERB
cet-15445	9	6	demand	demand	NOUN
cet-15445	9	7	for	for	ADP
cet-15445	9	8	high	high	ADJ
cet-15445	9	9	-	-	PUNCT
cet-15445	9	10	quality	quality	NOUN
cet-15445	9	11	products	product	NOUN
cet-15445	9	12	in	in	ADP
cet-15445	9	13	nutraceutical	nutraceutical	ADJ
cet-15445	9	14	and	and	CCONJ
cet-15445	9	15	pharmaceutical	pharmaceutical	NOUN
cet-15445	9	16	fields	field	NOUN
cet-15445	9	17	has	have	AUX
cet-15445	9	18	highlighted	highlight	VERB
cet-15445	9	19	the	the	DET
cet-15445	9	20	need	need	NOUN
cet-15445	9	21	for	for	ADP
cet-15445	9	22	innovative	innovative	ADJ
cet-15445	9	23	technologies	technology	NOUN
cet-15445	9	24	capable	capable	ADJ
cet-15445	9	25	of	of	ADP
cet-15445	9	26	overcoming	overcome	VERB
cet-15445	9	27	the	the	DET
cet-15445	9	28	limitations	limitation	NOUN
cet-15445	9	29	of	of	ADP
cet-15445	9	30	traditional	traditional	ADJ
cet-15445	9	31	manufacturing	manufacturing	NOUN
cet-15445	9	32	methods	method	NOUN
cet-15445	9	33	(	(	PUNCT
cet-15445	9	34	kailasapathy	kailasapathy	ADJ
cet-15445	9	35	,	,	PUNCT
cet-15445	9	36	2009	2009	NUM
cet-15445	9	37	)	)	PUNCT
cet-15445	9	38	.	.	PUNCT
cet-15445	10	1	drug	drug	NOUN
cet-15445	10	2	delivery	delivery	NOUN
cet-15445	10	3	systems	system	NOUN
cet-15445	10	4	,	,	PUNCT
cet-15445	10	5	essential	essential	ADJ
cet-15445	10	6	for	for	ADP
cet-15445	10	7	ensuring	ensure	VERB
cet-15445	10	8	effective	effective	ADJ
cet-15445	10	9	bioavailability	bioavailability	NOUN
cet-15445	10	10	and	and	CCONJ
cet-15445	10	11	targeted	target	VERB
cet-15445	10	12	delivery	delivery	NOUN
cet-15445	10	13	of	of	ADP
cet-15445	10	14	active	active	ADJ
cet-15445	10	15	ingredients	ingredient	NOUN
cet-15445	10	16	,	,	PUNCT
cet-15445	10	17	require	require	VERB
cet-15445	10	18	solutions	solution	NOUN
cet-15445	10	19	that	that	PRON
cet-15445	10	20	combine	combine	VERB
cet-15445	10	21	efficiency	efficiency	NOUN
cet-15445	10	22	,	,	PUNCT
cet-15445	10	23	sustainability	sustainability	NOUN
cet-15445	10	24	,	,	PUNCT
cet-15445	10	25	and	and	CCONJ
cet-15445	10	26	flexibility	flexibility	NOUN
cet-15445	10	27	in	in	ADP
cet-15445	10	28	handling	handle	VERB
cet-15445	10	29	complex	complex	ADJ
cet-15445	10	30	bioactive	bioactive	NOUN
cet-15445	10	31	compounds	compound	NOUN
cet-15445	10	32	at	at	ADP
cet-15445	10	33	nanometric	nanometric	ADJ
cet-15445	10	34	level	level	NOUN
cet-15445	10	35	(	(	PUNCT
cet-15445	10	36	kucuk	kucuk	NOUN
cet-15445	10	37	et	et	PROPN
cet-15445	10	38	al	al	PROPN
cet-15445	10	39	,	,	PUNCT
cet-15445	10	40	2023	2023	NUM
cet-15445	10	41	)	)	PUNCT
cet-15445	10	42	.	.	PUNCT
cet-15445	11	1	liposomes	liposome	NOUN
cet-15445	11	2	are	be	AUX
cet-15445	11	3	known	know	VERB
cet-15445	11	4	as	as	ADP
cet-15445	11	5	biocompatible	biocompatible	ADJ
cet-15445	11	6	drug	drug	NOUN
cet-15445	11	7	delivery	delivery	NOUN
cet-15445	11	8	systems	system	NOUN
cet-15445	11	9	,	,	PUNCT
cet-15445	11	10	due	due	ADP
cet-15445	11	11	to	to	ADP
cet-15445	11	12	their	their	PRON
cet-15445	11	13	affinity	affinity	NOUN
cet-15445	11	14	to	to	ADP
cet-15445	11	15	human	human	ADJ
cet-15445	11	16	cell	cell	NOUN
cet-15445	11	17	membranes	membrane	NOUN
cet-15445	11	18	.	.	PUNCT
cet-15445	12	1	however	however	ADV
cet-15445	12	2	,	,	PUNCT
cet-15445	12	3	liposomes	liposome	NOUN
cet-15445	12	4	conventional	conventional	ADJ
cet-15445	12	5	production	production	NOUN
cet-15445	12	6	methods	method	NOUN
cet-15445	12	7	often	often	ADV
cet-15445	12	8	face	face	VERB
cet-15445	12	9	critical	critical	ADJ
cet-15445	12	10	challenges	challenge	NOUN
cet-15445	12	11	that	that	PRON
cet-15445	12	12	hinder	hinder	VERB
cet-15445	12	13	their	their	PRON
cet-15445	12	14	effectiveness	effectiveness	NOUN
cet-15445	12	15	and	and	CCONJ
cet-15445	12	16	scalability	scalability	NOUN
cet-15445	12	17	.	.	PUNCT
cet-15445	13	1	according	accord	VERB
cet-15445	13	2	to	to	ADP
cet-15445	13	3	literature	literature	NOUN
cet-15445	13	4	(	(	PUNCT
cet-15445	13	5	trucillo	trucillo	NOUN
cet-15445	13	6	et	et	PROPN
cet-15445	13	7	al	al	PROPN
cet-15445	13	8	,	,	PUNCT
cet-15445	13	9	2020	2020	NUM
cet-15445	13	10	)	)	PUNCT
cet-15445	13	11	,	,	PUNCT
cet-15445	13	12	the	the	DET
cet-15445	13	13	ethanol	ethanol	NOUN
cet-15445	13	14	injection	injection	NOUN
cet-15445	13	15	(	(	PUNCT
cet-15445	13	16	ei	ei	NOUN
cet-15445	13	17	)	)	PUNCT
cet-15445	13	18	method	method	NOUN
cet-15445	13	19	forms	form	NOUN
cet-15445	13	20	liposomes	liposome	NOUN
cet-15445	13	21	by	by	ADP
cet-15445	13	22	injecting	inject	VERB
cet-15445	13	23	a	a	DET
cet-15445	13	24	lipid	lipid	NOUN
cet-15445	13	25	-	-	PUNCT
cet-15445	13	26	ethanol	ethanol	NOUN
cet-15445	13	27	solution	solution	NOUN
cet-15445	13	28	into	into	ADP
cet-15445	13	29	water	water	NOUN
cet-15445	13	30	,	,	PUNCT
cet-15445	13	31	but	but	CCONJ
cet-15445	13	32	it	it	PRON
cet-15445	13	33	leaves	leave	VERB
cet-15445	13	34	a	a	DET
cet-15445	13	35	high	high	ADJ
cet-15445	13	36	solvent	solvent	ADJ
cet-15445	13	37	residue	residue	NOUN
cet-15445	13	38	,	,	PUNCT
cet-15445	13	39	produces	produce	VERB
cet-15445	13	40	heterogeneous	heterogeneous	ADJ
cet-15445	13	41	vesicles	vesicle	NOUN
cet-15445	13	42	,	,	PUNCT
cet-15445	13	43	and	and	CCONJ
cet-15445	13	44	has	have	VERB
cet-15445	13	45	low	low	ADJ
cet-15445	13	46	encapsulation	encapsulation	NOUN
cet-15445	13	47	efficiency	efficiency	NOUN
cet-15445	13	48	,	,	PUNCT
cet-15445	13	49	especially	especially	ADV
cet-15445	13	50	for	for	ADP
cet-15445	13	51	hydrophilic	hydrophilic	ADJ
cet-15445	13	52	compounds	compound	NOUN
cet-15445	13	53	.	.	PUNCT
cet-15445	14	1	the	the	DET
cet-15445	14	2	thin	thin	ADJ
cet-15445	14	3	-	-	PUNCT
cet-15445	14	4	layer	layer	NOUN
cet-15445	14	5	hydration	hydration	NOUN
cet-15445	14	6	(	(	PUNCT
cet-15445	14	7	tlh	tlh	NOUN
cet-15445	14	8	)	)	PUNCT
cet-15445	14	9	method	method	NOUN
cet-15445	14	10	involves	involve	VERB
cet-15445	14	11	forming	form	VERB
cet-15445	14	12	a	a	DET
cet-15445	14	13	lipid	lipid	NOUN
cet-15445	14	14	film	film	NOUN
cet-15445	14	15	,	,	PUNCT
cet-15445	14	16	hydrating	hydrate	VERB
cet-15445	14	17	it	it	PRON
cet-15445	14	18	,	,	PUNCT
cet-15445	14	19	and	and	CCONJ
cet-15445	14	20	spontaneously	spontaneously	ADV
cet-15445	14	21	generating	generate	VERB
cet-15445	14	22	liposomes	liposome	NOUN
cet-15445	14	23	,	,	PUNCT
cet-15445	14	24	but	but	CCONJ
cet-15445	14	25	it	it	PRON
cet-15445	14	26	results	result	VERB
cet-15445	14	27	in	in	ADP
cet-15445	14	28	large	large	ADJ
cet-15445	14	29	,	,	PUNCT
cet-15445	14	30	irregular	irregular	ADJ
cet-15445	14	31	vesicles	vesicle	NOUN
cet-15445	14	32	with	with	ADP
cet-15445	14	33	low	low	ADJ
cet-15445	14	34	encapsulation	encapsulation	NOUN
cet-15445	14	35	efficiency	efficiency	NOUN
cet-15445	14	36	,	,	PUNCT
cet-15445	14	37	requiring	require	VERB
cet-15445	14	38	further	further	ADJ
cet-15445	14	39	processing	processing	NOUN
cet-15445	14	40	for	for	ADP
cet-15445	14	41	size	size	NOUN
cet-15445	14	42	control	control	NOUN
cet-15445	14	43	.	.	PUNCT
cet-15445	15	1	residual	residual	ADJ
cet-15445	15	2	solvent	solvent	NOUN
cet-15445	15	3	contamination	contamination	NOUN
cet-15445	15	4	is	be	AUX
cet-15445	15	5	a	a	DET
cet-15445	15	6	pervasive	pervasive	ADJ
cet-15445	15	7	issue	issue	NOUN
cet-15445	15	8	,	,	PUNCT
cet-15445	15	9	particularly	particularly	ADV
cet-15445	15	10	in	in	ADP
cet-15445	15	11	methods	method	NOUN
cet-15445	15	12	that	that	PRON
cet-15445	15	13	rely	rely	VERB
cet-15445	15	14	on	on	ADP
cet-15445	15	15	organic	organic	ADJ
cet-15445	15	16	solvents	solvent	NOUN
cet-15445	15	17	for	for	ADP
cet-15445	15	18	encapsulation	encapsulation	NOUN
cet-15445	15	19	,	,	PUNCT
cet-15445	15	20	such	such	DET
cet-15445	15	21	the	the	DET
cet-15445	15	22	conventional	conventional	ADJ
cet-15445	15	23	methods	method	NOUN
cet-15445	15	24	of	of	ADP
cet-15445	15	25	thin	thin	ADJ
cet-15445	15	26	-	-	PUNCT
cet-15445	15	27	film	film	NOUN
cet-15445	15	28	hydration	hydration	NOUN
cet-15445	15	29	or	or	CCONJ
cet-15445	15	30	ethanol	ethanol	NOUN
cet-15445	15	31	injection	injection	NOUN
cet-15445	15	32	(	(	PUNCT
cet-15445	15	33	gouda	gouda	NOUN
cet-15445	15	34	et	et	NOUN
cet-15445	15	35	al	al	PROPN
cet-15445	15	36	,	,	PUNCT
cet-15445	15	37	2021	2021	NUM
cet-15445	15	38	)	)	PUNCT
cet-15445	15	39	.	.	PUNCT
cet-15445	16	1	these	these	DET
cet-15445	16	2	residual	residual	ADJ
cet-15445	16	3	solvents	solvent	NOUN
cet-15445	16	4	not	not	PART
cet-15445	16	5	only	only	ADV
cet-15445	16	6	compromise	compromise	VERB
cet-15445	16	7	the	the	DET
cet-15445	16	8	safety	safety	NOUN
cet-15445	16	9	and	and	CCONJ
cet-15445	16	10	purity	purity	NOUN
cet-15445	16	11	of	of	ADP
cet-15445	16	12	the	the	DET
cet-15445	16	13	final	final	ADJ
cet-15445	16	14	product	product	NOUN
cet-15445	16	15	but	but	CCONJ
cet-15445	16	16	also	also	ADV
cet-15445	16	17	pose	pose	VERB
cet-15445	16	18	environmental	environmental	ADJ
cet-15445	16	19	and	and	CCONJ
cet-15445	16	20	regulatory	regulatory	ADJ
cet-15445	16	21	concerns	concern	NOUN
cet-15445	16	22	,	,	PUNCT
cet-15445	16	23	limiting	limit	VERB
cet-15445	16	24	their	their	PRON
cet-15445	16	25	acceptability	acceptability	NOUN
cet-15445	16	26	for	for	ADP
cet-15445	16	27	massive	massive	ADJ
cet-15445	16	28	use	use	NOUN
cet-15445	16	29	(	(	PUNCT
cet-15445	16	30	finotti	finotti	PROPN
cet-15445	16	31	cordeiro	cordeiro	PROPN
cet-15445	16	32	et	et	PROPN
cet-15445	16	33	al	al	PROPN
cet-15445	16	34	.	.	PROPN
cet-15445	16	35	,	,	PUNCT
cet-15445	16	36	2024	2024	NUM
cet-15445	16	37	)	)	PUNCT
cet-15445	16	38	.	.	PUNCT
cet-15445	17	1	moreover	moreover	ADV
cet-15445	17	2	,	,	PUNCT
cet-15445	17	3	low	low	ADJ
cet-15445	17	4	reproducibility	reproducibility	NOUN
cet-15445	17	5	remains	remain	VERB
cet-15445	17	6	a	a	DET
cet-15445	17	7	critical	critical	ADJ
cet-15445	17	8	drawback	drawback	NOUN
cet-15445	17	9	.	.	PUNCT
cet-15445	18	1	conventional	conventional	ADJ
cet-15445	18	2	processes	process	NOUN
cet-15445	18	3	suffer	suffer	VERB
cet-15445	18	4	from	from	ADP
cet-15445	18	5	difficult	difficult	ADJ
cet-15445	18	6	control	control	NOUN
cet-15445	18	7	over	over	ADP
cet-15445	18	8	particle	particle	NOUN
cet-15445	18	9	size	size	NOUN
cet-15445	18	10	,	,	PUNCT
cet-15445	18	11	morphology	morphology	NOUN
cet-15445	18	12	,	,	PUNCT
cet-15445	18	13	and	and	CCONJ
cet-15445	18	14	encapsulation	encapsulation	NOUN
cet-15445	18	15	efficiency	efficiency	NOUN
cet-15445	18	16	,	,	PUNCT
cet-15445	18	17	resulting	result	VERB
cet-15445	18	18	in	in	ADP
cet-15445	18	19	batch	batch	NOUN
cet-15445	18	20	-	-	PUNCT
cet-15445	18	21	to	to	ADP
cet-15445	18	22	-	-	PUNCT
cet-15445	18	23	batch	batch	NOUN
cet-15445	18	24	variability	variability	NOUN
cet-15445	18	25	(	(	PUNCT
cet-15445	18	26	lombardo	lombardo	PROPN
cet-15445	18	27	&	&	CCONJ
cet-15445	18	28	1165	1165	NUM
cet-15445	18	29	kiselev	kiselev	NOUN
cet-15445	18	30	,	,	PUNCT
cet-15445	18	31	2022	2022	NUM
cet-15445	18	32	)	)	PUNCT
cet-15445	18	33	.	.	PUNCT
cet-15445	19	1	this	this	DET
cet-15445	19	2	inconsistency	inconsistency	NOUN
cet-15445	19	3	can	can	AUX
cet-15445	19	4	significantly	significantly	ADV
cet-15445	19	5	reduce	reduce	VERB
cet-15445	19	6	the	the	DET
cet-15445	19	7	therapeutic	therapeutic	ADJ
cet-15445	19	8	efficacy	efficacy	NOUN
cet-15445	19	9	of	of	ADP
cet-15445	19	10	the	the	DET
cet-15445	19	11	drug	drug	NOUN
cet-15445	19	12	delivery	delivery	NOUN
cet-15445	19	13	systems	system	NOUN
cet-15445	19	14	,	,	PUNCT
cet-15445	19	15	with	with	ADP
cet-15445	19	16	significant	significant	ADJ
cet-15445	19	17	consequences	consequence	NOUN
cet-15445	19	18	to	to	PART
cet-15445	19	19	pass	pass	VERB
cet-15445	19	20	highly	highly	ADV
cet-15445	19	21	stringent	stringent	ADJ
cet-15445	19	22	quality	quality	NOUN
cet-15445	19	23	control	control	NOUN
cet-15445	19	24	standards	standard	NOUN
cet-15445	19	25	.	.	PUNCT
cet-15445	20	1	additionally	additionally	ADV
cet-15445	20	2	,	,	PUNCT
cet-15445	20	3	the	the	DET
cet-15445	20	4	low	low	ADJ
cet-15445	20	5	versatility	versatility	NOUN
cet-15445	20	6	of	of	ADP
cet-15445	20	7	these	these	DET
cet-15445	20	8	traditional	traditional	ADJ
cet-15445	20	9	methods	method	NOUN
cet-15445	20	10	is	be	AUX
cet-15445	20	11	strictly	strictly	ADV
cet-15445	20	12	related	relate	VERB
cet-15445	20	13	to	to	ADP
cet-15445	20	14	the	the	DET
cet-15445	20	15	impossibility	impossibility	NOUN
cet-15445	20	16	to	to	PART
cet-15445	20	17	successfully	successfully	ADV
cet-15445	20	18	process	process	VERB
cet-15445	20	19	different	different	ADJ
cet-15445	20	20	bioactive	bioactive	PROPN
cet-15445	20	21	compounds	compound	NOUN
cet-15445	20	22	.	.	PUNCT
cet-15445	21	1	encapsulation	encapsulation	NOUN
cet-15445	21	2	techniques	technique	NOUN
cet-15445	21	3	often	often	ADV
cet-15445	21	4	show	show	VERB
cet-15445	21	5	a	a	DET
cet-15445	21	6	preference	preference	NOUN
cet-15445	21	7	for	for	ADP
cet-15445	21	8	either	either	CCONJ
cet-15445	21	9	hydrophilic	hydrophilic	ADJ
cet-15445	21	10	or	or	CCONJ
cet-15445	21	11	lipophilic	lipophilic	ADJ
cet-15445	21	12	molecules	molecule	NOUN
cet-15445	21	13	,	,	PUNCT
cet-15445	21	14	making	make	VERB
cet-15445	21	15	it	it	PRON
cet-15445	21	16	difficult	difficult	ADJ
cet-15445	21	17	to	to	PART
cet-15445	21	18	achieve	achieve	VERB
cet-15445	21	19	efficient	efficient	ADJ
cet-15445	21	20	encapsulation	encapsulation	NOUN
cet-15445	21	21	for	for	ADP
cet-15445	21	22	complex	complex	ADJ
cet-15445	21	23	formulations	formulation	NOUN
cet-15445	21	24	that	that	PRON
cet-15445	21	25	involve	involve	VERB
cet-15445	21	26	both	both	DET
cet-15445	21	27	types	type	NOUN
cet-15445	21	28	of	of	ADP
cet-15445	21	29	compounds	compound	NOUN
cet-15445	21	30	.	.	PUNCT
cet-15445	22	1	this	this	DET
cet-15445	22	2	limitation	limitation	NOUN
cet-15445	22	3	reduces	reduce	VERB
cet-15445	22	4	their	their	PRON
cet-15445	22	5	applicability	applicability	NOUN
cet-15445	22	6	in	in	ADP
cet-15445	22	7	multifunctional	multifunctional	ADJ
cet-15445	22	8	drug	drug	NOUN
cet-15445	22	9	delivery	delivery	NOUN
cet-15445	22	10	systems	system	NOUN
cet-15445	22	11	,	,	PUNCT
cet-15445	22	12	where	where	SCONJ
cet-15445	22	13	the	the	DET
cet-15445	22	14	simultaneous	simultaneous	ADJ
cet-15445	22	15	delivery	delivery	NOUN
cet-15445	22	16	of	of	ADP
cet-15445	22	17	various	various	ADJ
cet-15445	22	18	active	active	ADJ
cet-15445	22	19	ingredients	ingredient	NOUN
cet-15445	22	20	may	may	AUX
cet-15445	22	21	be	be	AUX
cet-15445	22	22	required	require	VERB
cet-15445	22	23	.	.	PUNCT
cet-15445	23	1	therefore	therefore	ADV
cet-15445	23	2	,	,	PUNCT
cet-15445	23	3	advanced	advanced	ADJ
cet-15445	23	4	manufacturing	manufacturing	NOUN
cet-15445	23	5	approaches	approach	NOUN
cet-15445	23	6	must	must	AUX
cet-15445	23	7	overcome	overcome	VERB
cet-15445	23	8	these	these	DET
cet-15445	23	9	drawbacks	drawback	NOUN
cet-15445	23	10	while	while	SCONJ
cet-15445	23	11	meeting	meet	VERB
cet-15445	23	12	the	the	DET
cet-15445	23	13	growing	grow	VERB
cet-15445	23	14	demands	demand	NOUN
cet-15445	23	15	for	for	ADP
cet-15445	23	16	sustainable	sustainable	ADJ
cet-15445	23	17	,	,	PUNCT
cet-15445	23	18	high	high	ADJ
cet-15445	23	19	-	-	PUNCT
cet-15445	23	20	performance	performance	NOUN
cet-15445	23	21	drug	drug	NOUN
cet-15445	23	22	delivery	delivery	NOUN
cet-15445	23	23	systems	system	NOUN
cet-15445	23	24	.	.	PUNCT
cet-15445	24	1	supercritical	supercritical	ADJ
cet-15445	24	2	particle	particle	NOUN
cet-15445	24	3	formation	formation	NOUN
cet-15445	24	4	(	(	PUNCT
cet-15445	24	5	spaf	spaf	NOUN
cet-15445	24	6	)	)	PUNCT
cet-15445	24	7	process	process	NOUN
cet-15445	24	8	represents	represent	VERB
cet-15445	24	9	a	a	DET
cet-15445	24	10	significant	significant	ADJ
cet-15445	24	11	breakthrough	breakthrough	NOUN
cet-15445	24	12	,	,	PUNCT
cet-15445	24	13	offering	offer	VERB
cet-15445	24	14	an	an	DET
cet-15445	24	15	innovative	innovative	ADJ
cet-15445	24	16	and	and	CCONJ
cet-15445	24	17	eco	eco	NOUN
cet-15445	24	18	-	-	PUNCT
cet-15445	24	19	friendly	friendly	ADJ
cet-15445	24	20	alternative	alternative	NOUN
cet-15445	24	21	to	to	ADP
cet-15445	24	22	current	current	ADJ
cet-15445	24	23	techniques	technique	NOUN
cet-15445	24	24	(	(	PUNCT
cet-15445	24	25	sofia	sofia	PROPN
cet-15445	24	26	et	et	PROPN
cet-15445	24	27	al	al	PROPN
cet-15445	24	28	,	,	PUNCT
cet-15445	24	29	2025	2025	NUM
cet-15445	24	30	)	)	PUNCT
cet-15445	24	31	.	.	PUNCT
cet-15445	25	1	by	by	ADP
cet-15445	25	2	leveraging	leverage	VERB
cet-15445	25	3	supercritical	supercritical	ADJ
cet-15445	25	4	fluids	fluid	NOUN
cet-15445	25	5	,	,	PUNCT
cet-15445	25	6	the	the	DET
cet-15445	25	7	spaf	spaf	PROPN
cet-15445	25	8	process	process	NOUN
cet-15445	25	9	eliminates	eliminate	VERB
cet-15445	25	10	solvent	solvent	ADJ
cet-15445	25	11	residues	residue	NOUN
cet-15445	25	12	,	,	PUNCT
cet-15445	25	13	ensuring	ensure	VERB
cet-15445	25	14	a	a	DET
cet-15445	25	15	clean	clean	ADJ
cet-15445	25	16	and	and	CCONJ
cet-15445	25	17	safe	safe	ADJ
cet-15445	25	18	final	final	ADJ
cet-15445	25	19	product	product	NOUN
cet-15445	25	20	.	.	PUNCT
cet-15445	26	1	furthermore	furthermore	ADV
cet-15445	26	2	,	,	PUNCT
cet-15445	26	3	this	this	DET
cet-15445	26	4	technique	technique	NOUN
cet-15445	26	5	enables	enable	VERB
cet-15445	26	6	the	the	DET
cet-15445	26	7	coupling	coupling	NOUN
cet-15445	26	8	of	of	ADP
cet-15445	26	9	hydrophilic	hydrophilic	ADJ
cet-15445	26	10	and	and	CCONJ
cet-15445	26	11	lipophilic	lipophilic	ADJ
cet-15445	26	12	compounds	compound	NOUN
cet-15445	26	13	with	with	ADP
cet-15445	26	14	polymeric	polymeric	ADJ
cet-15445	26	15	or	or	CCONJ
cet-15445	26	16	lipidic	lipidic	ADJ
cet-15445	26	17	carriers	carrier	NOUN
cet-15445	26	18	while	while	SCONJ
cet-15445	26	19	maintaining	maintain	VERB
cet-15445	26	20	precise	precise	ADJ
cet-15445	26	21	control	control	NOUN
cet-15445	26	22	over	over	ADP
cet-15445	26	23	particle	particle	NOUN
cet-15445	26	24	size	size	NOUN
cet-15445	26	25	distribution	distribution	NOUN
cet-15445	26	26	,	,	PUNCT
cet-15445	26	27	morphology	morphology	NOUN
cet-15445	26	28	,	,	PUNCT
cet-15445	26	29	release	release	NOUN
cet-15445	26	30	profiles	profile	NOUN
cet-15445	26	31	,	,	PUNCT
cet-15445	26	32	and	and	CCONJ
cet-15445	26	33	the	the	DET
cet-15445	26	34	bioavailability	bioavailability	NOUN
cet-15445	26	35	of	of	ADP
cet-15445	26	36	active	active	ADJ
cet-15445	26	37	ingredients	ingredient	NOUN
cet-15445	26	38	.	.	PUNCT
cet-15445	27	1	a	a	DET
cet-15445	27	2	further	further	ADJ
cet-15445	27	3	enhancement	enhancement	NOUN
cet-15445	27	4	in	in	ADP
cet-15445	27	5	the	the	DET
cet-15445	27	6	quality	quality	NOUN
cet-15445	27	7	and	and	CCONJ
cet-15445	27	8	stability	stability	NOUN
cet-15445	27	9	of	of	ADP
cet-15445	27	10	products	product	NOUN
cet-15445	27	11	obtained	obtain	VERB
cet-15445	27	12	through	through	ADP
cet-15445	27	13	spaf	spaf	PROPN
cet-15445	27	14	is	be	AUX
cet-15445	27	15	achieved	achieve	VERB
cet-15445	27	16	by	by	ADP
cet-15445	27	17	integrating	integrate	VERB
cet-15445	27	18	a	a	DET
cet-15445	27	19	freeze	freeze	NOUN
cet-15445	27	20	-	-	PUNCT
cet-15445	27	21	drying	dry	VERB
cet-15445	27	22	process	process	NOUN
cet-15445	27	23	unit	unit	NOUN
cet-15445	27	24	.	.	PUNCT
cet-15445	28	1	this	this	DET
cet-15445	28	2	step	step	NOUN
cet-15445	28	3	transforms	transform	VERB
cet-15445	28	4	liquid	liquid	ADJ
cet-15445	28	5	suspensions	suspension	NOUN
cet-15445	28	6	of	of	ADP
cet-15445	28	7	carriers	carrier	NOUN
cet-15445	28	8	into	into	ADP
cet-15445	28	9	powders	powder	NOUN
cet-15445	28	10	that	that	PRON
cet-15445	28	11	remain	remain	VERB
cet-15445	28	12	stable	stable	ADJ
cet-15445	28	13	for	for	ADP
cet-15445	28	14	over	over	ADP
cet-15445	28	15	two	two	NUM
cet-15445	28	16	years	year	NOUN
cet-15445	28	17	,	,	PUNCT
cet-15445	28	18	ensuring	ensure	VERB
cet-15445	28	19	long	long	ADJ
cet-15445	28	20	-	-	PUNCT
cet-15445	28	21	term	term	NOUN
cet-15445	28	22	preservation	preservation	NOUN
cet-15445	28	23	and	and	CCONJ
cet-15445	28	24	readiness	readiness	NOUN
cet-15445	28	25	for	for	ADP
cet-15445	28	26	global	global	ADJ
cet-15445	28	27	market	market	NOUN
cet-15445	28	28	distribution	distribution	NOUN
cet-15445	28	29	.	.	PUNCT
cet-15445	29	1	the	the	DET
cet-15445	29	2	synergy	synergy	NOUN
cet-15445	29	3	between	between	ADP
cet-15445	29	4	supercritical	supercritical	ADJ
cet-15445	29	5	particle	particle	NOUN
cet-15445	29	6	formation	formation	NOUN
cet-15445	29	7	and	and	CCONJ
cet-15445	29	8	lyophilization	lyophilization	NOUN
cet-15445	29	9	not	not	PART
cet-15445	29	10	only	only	ADV
cet-15445	29	11	improves	improve	VERB
cet-15445	29	12	the	the	DET
cet-15445	29	13	pharmacokinetic	pharmacokinetic	ADJ
cet-15445	29	14	properties	property	NOUN
cet-15445	29	15	of	of	ADP
cet-15445	29	16	delivery	delivery	NOUN
cet-15445	29	17	systems	system	NOUN
cet-15445	29	18	but	but	CCONJ
cet-15445	29	19	also	also	ADV
cet-15445	29	20	provides	provide	VERB
cet-15445	29	21	a	a	DET
cet-15445	29	22	scalable	scalable	ADJ
cet-15445	29	23	and	and	CCONJ
cet-15445	29	24	sustainable	sustainable	ADJ
cet-15445	29	25	production	production	NOUN
cet-15445	29	26	platform	platform	NOUN
cet-15445	29	27	capable	capable	ADJ
cet-15445	29	28	of	of	ADP
cet-15445	29	29	meeting	meet	VERB
cet-15445	29	30	industrial	industrial	ADJ
cet-15445	29	31	demands	demand	NOUN
cet-15445	29	32	.	.	PUNCT
cet-15445	30	1	among	among	ADP
cet-15445	30	2	the	the	DET
cet-15445	30	3	numerous	numerous	ADJ
cet-15445	30	4	molecules	molecule	NOUN
cet-15445	30	5	available	available	ADJ
cet-15445	30	6	in	in	ADP
cet-15445	30	7	the	the	DET
cet-15445	30	8	market	market	NOUN
cet-15445	30	9	and	and	CCONJ
cet-15445	30	10	currently	currently	ADV
cet-15445	30	11	lacking	lack	VERB
cet-15445	30	12	a	a	DET
cet-15445	30	13	significant	significant	ADJ
cet-15445	30	14	bioavailability	bioavailability	NOUN
cet-15445	30	15	for	for	ADP
cet-15445	30	16	humans	human	NOUN
cet-15445	30	17	,	,	PUNCT
cet-15445	30	18	three	three	NUM
cet-15445	30	19	specific	specific	ADJ
cet-15445	30	20	molecules	molecule	NOUN
cet-15445	30	21	were	be	AUX
cet-15445	30	22	selected	select	VERB
cet-15445	30	23	for	for	ADP
cet-15445	30	24	liposomes	liposome	NOUN
cet-15445	30	25	encapsulation	encapsulation	NOUN
cet-15445	30	26	using	use	VERB
cet-15445	30	27	spaf	spaf	PROPN
cet-15445	30	28	technology	technology	NOUN
cet-15445	30	29	.	.	PUNCT
cet-15445	31	1	the	the	DET
cet-15445	31	2	first	first	ADJ
cet-15445	31	3	chosen	choose	VERB
cet-15445	31	4	molecule	molecule	NOUN
cet-15445	31	5	was	be	AUX
cet-15445	31	6	vitamin	vitamin	NOUN
cet-15445	31	7	b12	b12	NOUN
cet-15445	31	8	,	,	PUNCT
cet-15445	31	9	also	also	ADV
cet-15445	31	10	known	know	VERB
cet-15445	31	11	as	as	ADP
cet-15445	31	12	cobalamin	cobalamin	NOUN
cet-15445	31	13	,	,	PUNCT
cet-15445	31	14	is	be	AUX
cet-15445	31	15	a	a	DET
cet-15445	31	16	water	water	NOUN
cet-15445	31	17	-	-	PUNCT
cet-15445	31	18	soluble	soluble	ADJ
cet-15445	31	19	vitamin	vitamin	NOUN
cet-15445	31	20	essential	essential	ADJ
cet-15445	31	21	for	for	ADP
cet-15445	31	22	various	various	ADJ
cet-15445	31	23	physiological	physiological	ADJ
cet-15445	31	24	functions	function	NOUN
cet-15445	31	25	,	,	PUNCT
cet-15445	31	26	including	include	VERB
cet-15445	31	27	dna	dna	NOUN
cet-15445	31	28	synthesis	synthesis	NOUN
cet-15445	31	29	,	,	PUNCT
cet-15445	31	30	red	red	ADJ
cet-15445	31	31	blood	blood	NOUN
cet-15445	31	32	cell	cell	NOUN
cet-15445	31	33	formation	formation	NOUN
cet-15445	31	34	,	,	PUNCT
cet-15445	31	35	and	and	CCONJ
cet-15445	31	36	neurological	neurological	ADJ
cet-15445	31	37	health	health	NOUN
cet-15445	31	38	.	.	PUNCT
cet-15445	32	1	vitamin	vitamin	NOUN
cet-15445	32	2	b12	b12	NOUN
cet-15445	32	3	is	be	AUX
cet-15445	32	4	fundamental	fundamental	ADJ
cet-15445	32	5	in	in	ADP
cet-15445	32	6	the	the	DET
cet-15445	32	7	metabolism	metabolism	NOUN
cet-15445	32	8	of	of	ADP
cet-15445	32	9	every	every	DET
cet-15445	32	10	cell	cell	NOUN
cet-15445	32	11	in	in	ADP
cet-15445	32	12	the	the	DET
cet-15445	32	13	human	human	ADJ
cet-15445	32	14	body	body	NOUN
cet-15445	32	15	,	,	PUNCT
cet-15445	32	16	particularly	particularly	ADV
cet-15445	32	17	affecting	affect	VERB
cet-15445	32	18	the	the	DET
cet-15445	32	19	production	production	NOUN
cet-15445	32	20	of	of	ADP
cet-15445	32	21	energy	energy	NOUN
cet-15445	32	22	and	and	CCONJ
cet-15445	32	23	the	the	DET
cet-15445	32	24	synthesis	synthesis	NOUN
cet-15445	32	25	of	of	ADP
cet-15445	32	26	fatty	fatty	ADJ
cet-15445	32	27	acids	acid	NOUN
cet-15445	32	28	and	and	CCONJ
cet-15445	32	29	amino	amino	ADJ
cet-15445	32	30	acids	acid	NOUN
cet-15445	32	31	.	.	PUNCT
cet-15445	33	1	being	be	AUX
cet-15445	33	2	naturally	naturally	ADV
cet-15445	33	3	found	find	VERB
cet-15445	33	4	in	in	ADP
cet-15445	33	5	animal	animal	NOUN
cet-15445	33	6	-	-	PUNCT
cet-15445	33	7	based	base	VERB
cet-15445	33	8	foods	food	NOUN
cet-15445	33	9	such	such	ADJ
cet-15445	33	10	as	as	ADP
cet-15445	33	11	meat	meat	NOUN
cet-15445	33	12	,	,	PUNCT
cet-15445	33	13	fish	fish	NOUN
cet-15445	33	14	,	,	PUNCT
cet-15445	33	15	eggs	egg	NOUN
cet-15445	33	16	,	,	PUNCT
cet-15445	33	17	and	and	CCONJ
cet-15445	33	18	dairy	dairy	NOUN
cet-15445	33	19	products	product	NOUN
cet-15445	33	20	,	,	PUNCT
cet-15445	33	21	it	it	PRON
cet-15445	33	22	is	be	AUX
cet-15445	33	23	used	use	VERB
cet-15445	33	24	as	as	ADP
cet-15445	33	25	a	a	DET
cet-15445	33	26	dietary	dietary	ADJ
cet-15445	33	27	supplement	supplement	NOUN
cet-15445	33	28	for	for	ADP
cet-15445	33	29	vegetarians	vegetarian	NOUN
cet-15445	33	30	,	,	PUNCT
cet-15445	33	31	vegans	vegan	NOUN
cet-15445	33	32	,	,	PUNCT
cet-15445	33	33	and	and	CCONJ
cet-15445	33	34	individuals	individual	NOUN
cet-15445	33	35	with	with	ADP
cet-15445	33	36	absorption	absorption	NOUN
cet-15445	33	37	issues	issue	NOUN
cet-15445	33	38	.	.	PUNCT
cet-15445	34	1	a	a	DET
cet-15445	34	2	deficiency	deficiency	NOUN
cet-15445	34	3	in	in	ADP
cet-15445	34	4	vitamin	vitamin	NOUN
cet-15445	34	5	b12	b12	NOUN
cet-15445	34	6	can	can	AUX
cet-15445	34	7	lead	lead	VERB
cet-15445	34	8	to	to	ADP
cet-15445	34	9	anemia	anemia	NOUN
cet-15445	34	10	,	,	PUNCT
cet-15445	34	11	fatigue	fatigue	NOUN
cet-15445	34	12	,	,	PUNCT
cet-15445	34	13	and	and	CCONJ
cet-15445	34	14	neurological	neurological	ADJ
cet-15445	34	15	disorders	disorder	NOUN
cet-15445	34	16	,	,	PUNCT
cet-15445	34	17	highlighting	highlight	VERB
cet-15445	34	18	its	its	PRON
cet-15445	34	19	importance	importance	NOUN
cet-15445	34	20	for	for	ADP
cet-15445	34	21	overall	overall	ADJ
cet-15445	34	22	health	health	NOUN
cet-15445	34	23	and	and	CCONJ
cet-15445	34	24	well	well	ADV
cet-15445	34	25	-	-	PUNCT
cet-15445	34	26	being	be	AUX
cet-15445	34	27	(	(	PUNCT
cet-15445	34	28	marchianò	marchianò	NOUN
cet-15445	34	29	et	et	PROPN
cet-15445	34	30	al	al	PROPN
cet-15445	34	31	,	,	PUNCT
cet-15445	34	32	2022	2022	NUM
cet-15445	34	33	)	)	PUNCT
cet-15445	34	34	.	.	PUNCT
cet-15445	35	1	a	a	DET
cet-15445	35	2	second	second	ADJ
cet-15445	35	3	molecule	molecule	NOUN
cet-15445	35	4	entrapped	entrap	VERB
cet-15445	35	5	in	in	ADP
cet-15445	35	6	liposomes	liposome	NOUN
cet-15445	35	7	in	in	ADP
cet-15445	35	8	this	this	DET
cet-15445	35	9	work	work	NOUN
cet-15445	35	10	was	be	AUX
cet-15445	35	11	melatonin	melatonin	NOUN
cet-15445	35	12	,	,	PUNCT
cet-15445	35	13	a	a	DET
cet-15445	35	14	naturally	naturally	ADV
cet-15445	35	15	occurring	occur	VERB
cet-15445	35	16	hormone	hormone	NOUN
cet-15445	35	17	produced	produce	VERB
cet-15445	35	18	by	by	ADP
cet-15445	35	19	the	the	DET
cet-15445	35	20	pineal	pineal	NOUN
cet-15445	35	21	gland	gland	NOUN
cet-15445	35	22	in	in	ADP
cet-15445	35	23	the	the	DET
cet-15445	35	24	brain	brain	NOUN
cet-15445	35	25	,	,	PUNCT
cet-15445	35	26	primarily	primarily	ADV
cet-15445	35	27	responsible	responsible	ADJ
cet-15445	35	28	for	for	ADP
cet-15445	35	29	regulating	regulate	VERB
cet-15445	35	30	the	the	DET
cet-15445	35	31	sleep	sleep	NOUN
cet-15445	35	32	-	-	PUNCT
cet-15445	35	33	wake	wake	NOUN
cet-15445	35	34	cycle	cycle	NOUN
cet-15445	35	35	,	,	PUNCT
cet-15445	35	36	also	also	ADV
cet-15445	35	37	known	know	VERB
cet-15445	35	38	as	as	ADP
cet-15445	35	39	the	the	DET
cet-15445	35	40	circadian	circadian	ADJ
cet-15445	35	41	rhythm	rhythm	NOUN
cet-15445	35	42	.	.	PUNCT
cet-15445	36	1	its	its	PRON
cet-15445	36	2	production	production	NOUN
cet-15445	36	3	increases	increase	NOUN
cet-15445	36	4	in	in	ADP
cet-15445	36	5	response	response	NOUN
cet-15445	36	6	to	to	ADP
cet-15445	36	7	darkness	darkness	NOUN
cet-15445	36	8	,	,	PUNCT
cet-15445	36	9	promoting	promote	VERB
cet-15445	36	10	sleep	sleep	NOUN
cet-15445	36	11	,	,	PUNCT
cet-15445	36	12	and	and	CCONJ
cet-15445	36	13	decreases	decrease	VERB
cet-15445	36	14	with	with	ADP
cet-15445	36	15	exposure	exposure	NOUN
cet-15445	36	16	to	to	ADP
cet-15445	36	17	light	light	NOUN
cet-15445	36	18	.	.	PUNCT
cet-15445	37	1	beyond	beyond	ADP
cet-15445	37	2	its	its	PRON
cet-15445	37	3	role	role	NOUN
cet-15445	37	4	in	in	ADP
cet-15445	37	5	sleep	sleep	NOUN
cet-15445	37	6	regulation	regulation	NOUN
cet-15445	37	7	,	,	PUNCT
cet-15445	37	8	melatonin	melatonin	NOUN
cet-15445	37	9	is	be	AUX
cet-15445	37	10	also	also	ADV
cet-15445	37	11	a	a	DET
cet-15445	37	12	potent	potent	ADJ
cet-15445	37	13	antioxidant	antioxidant	NOUN
cet-15445	37	14	and	and	CCONJ
cet-15445	37	15	supports	support	VERB
cet-15445	37	16	immune	immune	ADJ
cet-15445	37	17	function	function	NOUN
cet-15445	37	18	.	.	PUNCT
cet-15445	38	1	it	it	PRON
cet-15445	38	2	is	be	AUX
cet-15445	38	3	commonly	commonly	ADV
cet-15445	38	4	used	use	VERB
cet-15445	38	5	as	as	ADP
cet-15445	38	6	a	a	DET
cet-15445	38	7	supplement	supplement	NOUN
cet-15445	38	8	to	to	PART
cet-15445	38	9	address	address	VERB
cet-15445	38	10	sleep	sleep	NOUN
cet-15445	38	11	disorders	disorder	NOUN
cet-15445	38	12	,	,	PUNCT
cet-15445	38	13	jet	jet	NOUN
cet-15445	38	14	lag	lag	NOUN
cet-15445	38	15	,	,	PUNCT
cet-15445	38	16	and	and	CCONJ
cet-15445	38	17	issues	issue	NOUN
cet-15445	38	18	related	relate	VERB
cet-15445	38	19	to	to	PART
cet-15445	38	20	shift	shift	VERB
cet-15445	38	21	work	work	NOUN
cet-15445	38	22	.	.	PUNCT
cet-15445	39	1	with	with	ADP
cet-15445	39	2	its	its	PRON
cet-15445	39	3	natural	natural	ADJ
cet-15445	39	4	origins	origin	NOUN
cet-15445	39	5	and	and	CCONJ
cet-15445	39	6	wide	wide	ADJ
cet-15445	39	7	range	range	NOUN
cet-15445	39	8	of	of	ADP
cet-15445	39	9	benefits	benefit	NOUN
cet-15445	39	10	,	,	PUNCT
cet-15445	39	11	melatonin	melatonin	NOUN
cet-15445	39	12	plays	play	VERB
cet-15445	39	13	a	a	DET
cet-15445	39	14	crucial	crucial	ADJ
cet-15445	39	15	role	role	NOUN
cet-15445	39	16	in	in	ADP
cet-15445	39	17	maintaining	maintain	VERB
cet-15445	39	18	overall	overall	ADJ
cet-15445	39	19	health	health	NOUN
cet-15445	39	20	and	and	CCONJ
cet-15445	39	21	well	well	ADV
cet-15445	39	22	-	-	PUNCT
cet-15445	39	23	being	be	AUX
cet-15445	39	24	(	(	PUNCT
cet-15445	39	25	dubey	dubey	PROPN
cet-15445	39	26	et	et	PROPN
cet-15445	39	27	al	al	PROPN
cet-15445	39	28	,	,	PUNCT
cet-15445	39	29	2007	2007	NUM
cet-15445	39	30	)	)	PUNCT
cet-15445	39	31	.	.	PUNCT
cet-15445	40	1	a	a	DET
cet-15445	40	2	third	third	ADJ
cet-15445	40	3	very	very	ADV
cet-15445	40	4	different	different	ADJ
cet-15445	40	5	molecule	molecule	NOUN
cet-15445	40	6	considered	consider	VERB
cet-15445	40	7	as	as	ADP
cet-15445	40	8	an	an	DET
cet-15445	40	9	alternative	alternative	NOUN
cet-15445	40	10	to	to	ADP
cet-15445	40	11	current	current	ADJ
cet-15445	40	12	iron	iron	NOUN
cet-15445	40	13	dietary	dietary	ADJ
cet-15445	40	14	supplements	supplement	NOUN
cet-15445	40	15	is	be	AUX
cet-15445	40	16	ferrous	ferrous	ADJ
cet-15445	40	17	sulfate	sulfate	NOUN
cet-15445	40	18	,	,	PUNCT
cet-15445	40	19	commonly	commonly	ADV
cet-15445	40	20	used	use	VERB
cet-15445	40	21	as	as	ADP
cet-15445	40	22	a	a	DET
cet-15445	40	23	dietary	dietary	ADJ
cet-15445	40	24	supplement	supplement	NOUN
cet-15445	40	25	to	to	PART
cet-15445	40	26	treat	treat	VERB
cet-15445	40	27	and	and	CCONJ
cet-15445	40	28	prevent	prevent	VERB
cet-15445	40	29	iron	iron	NOUN
cet-15445	40	30	deficiency	deficiency	NOUN
cet-15445	40	31	anemia	anemia	NOUN
cet-15445	40	32	.	.	PUNCT
cet-15445	41	1	iron	iron	NOUN
cet-15445	41	2	is	be	AUX
cet-15445	41	3	a	a	DET
cet-15445	41	4	vital	vital	ADJ
cet-15445	41	5	mineral	mineral	NOUN
cet-15445	41	6	necessary	necessary	ADJ
cet-15445	41	7	to	to	PART
cet-15445	41	8	produce	produce	VERB
cet-15445	41	9	hemoglobin	hemoglobin	NOUN
cet-15445	41	10	,	,	PUNCT
cet-15445	41	11	a	a	DET
cet-15445	41	12	protein	protein	NOUN
cet-15445	41	13	in	in	ADP
cet-15445	41	14	red	red	ADJ
cet-15445	41	15	blood	blood	NOUN
cet-15445	41	16	cells	cell	NOUN
cet-15445	41	17	that	that	PRON
cet-15445	41	18	carries	carry	VERB
cet-15445	41	19	oxygen	oxygen	NOUN
cet-15445	41	20	throughout	throughout	ADP
cet-15445	41	21	the	the	DET
cet-15445	41	22	body	body	NOUN
cet-15445	41	23	.	.	PUNCT
cet-15445	42	1	ferrous	ferrous	ADJ
cet-15445	42	2	sulphate	sulphate	NOUN
cet-15445	42	3	is	be	AUX
cet-15445	42	4	known	know	VERB
cet-15445	42	5	for	for	ADP
cet-15445	42	6	its	its	PRON
cet-15445	42	7	ability	ability	NOUN
cet-15445	42	8	to	to	PART
cet-15445	42	9	restore	restore	VERB
cet-15445	42	10	iron	iron	NOUN
cet-15445	42	11	levels	level	NOUN
cet-15445	42	12	in	in	ADP
cet-15445	42	13	individuals	individual	NOUN
cet-15445	42	14	with	with	ADP
cet-15445	42	15	deficiencies	deficiency	NOUN
cet-15445	42	16	caused	cause	VERB
cet-15445	42	17	by	by	ADP
cet-15445	42	18	poor	poor	ADJ
cet-15445	42	19	dietary	dietary	ADJ
cet-15445	42	20	intake	intake	NOUN
cet-15445	42	21	,	,	PUNCT
cet-15445	42	22	blood	blood	NOUN
cet-15445	42	23	loss	loss	NOUN
cet-15445	42	24	,	,	PUNCT
cet-15445	42	25	or	or	CCONJ
cet-15445	42	26	increased	increase	VERB
cet-15445	42	27	iron	iron	NOUN
cet-15445	42	28	requirements	requirement	NOUN
cet-15445	42	29	,	,	PUNCT
cet-15445	42	30	such	such	ADJ
cet-15445	42	31	as	as	ADP
cet-15445	42	32	during	during	ADP
cet-15445	42	33	pregnancy	pregnancy	NOUN
cet-15445	42	34	.	.	PUNCT
cet-15445	43	1	it	it	PRON
cet-15445	43	2	is	be	AUX
cet-15445	43	3	typically	typically	ADV
cet-15445	43	4	available	available	ADJ
cet-15445	43	5	in	in	ADP
cet-15445	43	6	tablet	tablet	NOUN
cet-15445	43	7	or	or	CCONJ
cet-15445	43	8	liquid	liquid	ADJ
cet-15445	43	9	form	form	NOUN
cet-15445	43	10	and	and	CCONJ
cet-15445	43	11	plays	play	VERB
cet-15445	43	12	a	a	DET
cet-15445	43	13	crucial	crucial	ADJ
cet-15445	43	14	role	role	NOUN
cet-15445	43	15	in	in	ADP
cet-15445	43	16	maintaining	maintain	VERB
cet-15445	43	17	energy	energy	NOUN
cet-15445	43	18	levels	level	NOUN
cet-15445	43	19	,	,	PUNCT
cet-15445	43	20	cognitive	cognitive	ADJ
cet-15445	43	21	function	function	NOUN
cet-15445	43	22	,	,	PUNCT
cet-15445	43	23	and	and	CCONJ
cet-15445	43	24	overall	overall	ADJ
cet-15445	43	25	health	health	NOUN
cet-15445	43	26	(	(	PUNCT
cet-15445	43	27	kosaraju	kosaraju	NOUN
cet-15445	43	28	et	et	PROPN
cet-15445	43	29	al	al	PROPN
cet-15445	43	30	,	,	PUNCT
cet-15445	43	31	2006	2006	NUM
cet-15445	43	32	)	)	PUNCT
cet-15445	43	33	.	.	PUNCT
cet-15445	44	1	this	this	DET
cet-15445	44	2	study	study	NOUN
cet-15445	44	3	aims	aim	VERB
cet-15445	44	4	to	to	PART
cet-15445	44	5	evaluate	evaluate	VERB
cet-15445	44	6	the	the	DET
cet-15445	44	7	benefits	benefit	NOUN
cet-15445	44	8	of	of	ADP
cet-15445	44	9	the	the	DET
cet-15445	44	10	spaf	spaf	PROPN
cet-15445	44	11	process	process	NOUN
cet-15445	44	12	in	in	ADP
cet-15445	44	13	terms	term	NOUN
cet-15445	44	14	of	of	ADP
cet-15445	44	15	yield	yield	NOUN
cet-15445	44	16	and	and	CCONJ
cet-15445	44	17	environmental	environmental	ADJ
cet-15445	44	18	impact	impact	NOUN
cet-15445	44	19	,	,	PUNCT
cet-15445	44	20	demonstrating	demonstrate	VERB
cet-15445	44	21	how	how	SCONJ
cet-15445	44	22	this	this	DET
cet-15445	44	23	technology	technology	NOUN
cet-15445	44	24	offers	offer	VERB
cet-15445	44	25	a	a	DET
cet-15445	44	26	viable	viable	ADJ
cet-15445	44	27	alternative	alternative	NOUN
cet-15445	44	28	to	to	ADP
cet-15445	44	29	conventional	conventional	ADJ
cet-15445	44	30	techniques	technique	NOUN
cet-15445	44	31	currently	currently	ADV
cet-15445	44	32	employed	employ	VERB
cet-15445	44	33	by	by	ADP
cet-15445	44	34	companies	company	NOUN
cet-15445	44	35	.	.	PUNCT
cet-15445	45	1	by	by	ADP
cet-15445	45	2	focusing	focus	VERB
cet-15445	45	3	on	on	ADP
cet-15445	45	4	three	three	NUM
cet-15445	45	5	distinct	distinct	ADJ
cet-15445	45	6	bioactive	bioactive	NOUN
cet-15445	45	7	compounds	compound	NOUN
cet-15445	45	8	,	,	PUNCT
cet-15445	45	9	this	this	DET
cet-15445	45	10	work	work	NOUN
cet-15445	45	11	explores	explore	VERB
cet-15445	45	12	the	the	DET
cet-15445	45	13	versatility	versatility	NOUN
cet-15445	45	14	of	of	ADP
cet-15445	45	15	the	the	DET
cet-15445	45	16	spaf	spaf	PROPN
cet-15445	45	17	process	process	NOUN
cet-15445	45	18	in	in	ADP
cet-15445	45	19	encapsulating	encapsulate	VERB
cet-15445	45	20	both	both	PRON
cet-15445	45	21	hydrophilic	hydrophilic	ADJ
cet-15445	45	22	and	and	CCONJ
cet-15445	45	23	lipophilic	lipophilic	ADJ
cet-15445	45	24	molecules	molecule	NOUN
cet-15445	45	25	within	within	ADP
cet-15445	45	26	lipid	lipid	NOUN
cet-15445	45	27	-	-	PUNCT
cet-15445	45	28	based	base	VERB
cet-15445	45	29	carriers	carrier	NOUN
cet-15445	45	30	.	.	PUNCT
cet-15445	46	1	specifically	specifically	ADV
cet-15445	46	2	,	,	PUNCT
cet-15445	46	3	the	the	DET
cet-15445	46	4	study	study	NOUN
cet-15445	46	5	investigates	investigate	VERB
cet-15445	46	6	how	how	SCONJ
cet-15445	46	7	spaf	spaf	PROPN
cet-15445	46	8	integrates	integrate	VERB
cet-15445	46	9	precise	precise	ADJ
cet-15445	46	10	particle	particle	NOUN
cet-15445	46	11	engineering	engineering	NOUN
cet-15445	46	12	,	,	PUNCT
cet-15445	46	13	encapsulation	encapsulation	NOUN
cet-15445	46	14	efficiency	efficiency	NOUN
cet-15445	46	15	,	,	PUNCT
cet-15445	46	16	and	and	CCONJ
cet-15445	46	17	environmental	environmental	ADJ
cet-15445	46	18	sustainability	sustainability	NOUN
cet-15445	46	19	into	into	ADP
cet-15445	46	20	a	a	DET
cet-15445	46	21	scalable	scalable	ADJ
cet-15445	46	22	production	production	NOUN
cet-15445	46	23	framework	framework	NOUN
cet-15445	46	24	.	.	PUNCT
cet-15445	47	1	the	the	DET
cet-15445	47	2	primary	primary	ADJ
cet-15445	47	3	goals	goal	NOUN
cet-15445	47	4	of	of	ADP
cet-15445	47	5	this	this	DET
cet-15445	47	6	research	research	NOUN
cet-15445	47	7	are	be	AUX
cet-15445	47	8	to	to	PART
cet-15445	47	9	assess	assess	VERB
cet-15445	47	10	the	the	DET
cet-15445	47	11	efficacy	efficacy	NOUN
cet-15445	47	12	of	of	ADP
cet-15445	47	13	spaf	spaf	PROPN
cet-15445	47	14	in	in	ADP
cet-15445	47	15	producing	produce	VERB
cet-15445	47	16	high	high	ADJ
cet-15445	47	17	-	-	PUNCT
cet-15445	47	18	quality	quality	NOUN
cet-15445	47	19	,	,	PUNCT
cet-15445	47	20	stable	stable	ADJ
cet-15445	47	21	powdered	powdered	ADJ
cet-15445	47	22	formulations	formulation	NOUN
cet-15445	47	23	with	with	ADP
cet-15445	47	24	extended	extended	ADJ
cet-15445	47	25	shelf	shelf	NOUN
cet-15445	47	26	-	-	PUNCT
cet-15445	47	27	life	life	NOUN
cet-15445	47	28	,	,	PUNCT
cet-15445	47	29	and	and	CCONJ
cet-15445	47	30	to	to	PART
cet-15445	47	31	highlight	highlight	VERB
cet-15445	47	32	its	its	PRON
cet-15445	47	33	advantages	advantage	NOUN
cet-15445	47	34	over	over	ADP
cet-15445	47	35	traditional	traditional	ADJ
cet-15445	47	36	methods	method	NOUN
cet-15445	47	37	in	in	ADP
cet-15445	47	38	terms	term	NOUN
cet-15445	47	39	of	of	ADP
cet-15445	47	40	reproducibility	reproducibility	NOUN
cet-15445	47	41	,	,	PUNCT
cet-15445	47	42	product	product	NOUN
cet-15445	47	43	purity	purity	NOUN
cet-15445	47	44	,	,	PUNCT
cet-15445	47	45	and	and	CCONJ
cet-15445	47	46	industrial	industrial	ADJ
cet-15445	47	47	scalability	scalability	NOUN
cet-15445	47	48	.	.	PUNCT
cet-15445	48	1	additionally	additionally	ADV
cet-15445	48	2	,	,	PUNCT
cet-15445	48	3	the	the	DET
cet-15445	48	4	study	study	NOUN
cet-15445	48	5	seeks	seek	VERB
cet-15445	48	6	to	to	PART
cet-15445	48	7	quantify	quantify	VERB
cet-15445	48	8	the	the	DET
cet-15445	48	9	yield	yield	NOUN
cet-15445	48	10	,	,	PUNCT
cet-15445	48	11	profitability	profitability	NOUN
cet-15445	48	12	,	,	PUNCT
cet-15445	48	13	and	and	CCONJ
cet-15445	48	14	environmental	environmental	ADJ
cet-15445	48	15	benefits	benefit	NOUN
cet-15445	48	16	of	of	ADP
cet-15445	48	17	spaf	spaf	PROPN
cet-15445	48	18	,	,	PUNCT
cet-15445	48	19	demonstrating	demonstrate	VERB
cet-15445	48	20	its	its	PRON
cet-15445	48	21	capacity	capacity	NOUN
cet-15445	48	22	to	to	PART
cet-15445	48	23	serve	serve	VERB
cet-15445	48	24	as	as	ADP
cet-15445	48	25	a	a	DET
cet-15445	48	26	viable	viable	ADJ
cet-15445	48	27	alternative	alternative	NOUN
cet-15445	48	28	for	for	ADP
cet-15445	48	29	modern	modern	ADJ
cet-15445	48	30	pharmaceutical	pharmaceutical	ADJ
cet-15445	48	31	and	and	CCONJ
cet-15445	48	32	nutraceutical	nutraceutical	ADJ
cet-15445	48	33	industries	industry	NOUN
cet-15445	48	34	.	.	PUNCT
cet-15445	49	1	2	2	X
cet-15445	49	2	.	.	X
cet-15445	49	3	materials	material	NOUN
cet-15445	49	4	and	and	CCONJ
cet-15445	49	5	methods	method	NOUN
cet-15445	49	6	the	the	DET
cet-15445	49	7	supercritical	supercritical	ADJ
cet-15445	49	8	particle	particle	NOUN
cet-15445	49	9	formation	formation	NOUN
cet-15445	49	10	(	(	PUNCT
cet-15445	49	11	spaf	spaf	NOUN
cet-15445	49	12	)	)	PUNCT
cet-15445	49	13	process	process	NOUN
cet-15445	49	14	is	be	AUX
cet-15445	49	15	an	an	DET
cet-15445	49	16	advanced	advanced	ADJ
cet-15445	49	17	method	method	NOUN
cet-15445	49	18	for	for	ADP
cet-15445	49	19	producing	produce	VERB
cet-15445	49	20	stable	stable	ADJ
cet-15445	49	21	powdered	powdered	ADJ
cet-15445	49	22	drug	drug	NOUN
cet-15445	49	23	delivery	delivery	NOUN
cet-15445	49	24	systems	system	NOUN
cet-15445	49	25	by	by	ADP
cet-15445	49	26	combining	combine	VERB
cet-15445	49	27	supercritical	supercritical	ADJ
cet-15445	49	28	co₂	co₂	NOUN
cet-15445	49	29	technology	technology	NOUN
cet-15445	49	30	with	with	ADP
cet-15445	49	31	drying	dry	VERB
cet-15445	49	32	techniques	technique	NOUN
cet-15445	49	33	like	like	ADP
cet-15445	49	34	freeze	freeze	VERB
cet-15445	49	35	-	-	PUNCT
cet-15445	49	36	drying	dry	VERB
cet-15445	49	37	and	and	CCONJ
cet-15445	49	38	1166	1166	NUM
cet-15445	49	39	spray	spray	VERB
cet-15445	49	40	drying	dry	VERB
cet-15445	49	41	.	.	PUNCT
cet-15445	50	1	it	it	PRON
cet-15445	50	2	eliminates	eliminate	VERB
cet-15445	50	3	harmful	harmful	ADJ
cet-15445	50	4	organic	organic	ADJ
cet-15445	50	5	solvents	solvent	NOUN
cet-15445	50	6	,	,	PUNCT
cet-15445	50	7	enhances	enhance	VERB
cet-15445	50	8	encapsulation	encapsulation	NOUN
cet-15445	50	9	efficiency	efficiency	NOUN
cet-15445	50	10	(	(	PUNCT
cet-15445	50	11	up	up	ADP
cet-15445	50	12	to	to	PART
cet-15445	50	13	94	94	NUM
cet-15445	50	14	%	%	NOUN
cet-15445	50	15	)	)	PUNCT
cet-15445	50	16	,	,	PUNCT
cet-15445	50	17	and	and	CCONJ
cet-15445	50	18	ensures	ensure	VERB
cet-15445	50	19	long	long	ADJ
cet-15445	50	20	-	-	PUNCT
cet-15445	50	21	term	term	NOUN
cet-15445	50	22	stability	stability	NOUN
cet-15445	50	23	of	of	ADP
cet-15445	50	24	powdered	powdered	ADJ
cet-15445	50	25	formulations	formulation	NOUN
cet-15445	50	26	(	(	PUNCT
cet-15445	50	27	more	more	ADJ
cet-15445	50	28	than	than	ADP
cet-15445	50	29	24	24	NUM
cet-15445	50	30	months	month	NOUN
cet-15445	50	31	)	)	PUNCT
cet-15445	50	32	.	.	PUNCT
cet-15445	51	1	the	the	DET
cet-15445	51	2	process	process	NOUN
cet-15445	51	3	involves	involve	VERB
cet-15445	51	4	high	high	ADJ
cet-15445	51	5	-	-	PUNCT
cet-15445	51	6	pressure	pressure	NOUN
cet-15445	51	7	mixing	mixing	NOUN
cet-15445	51	8	of	of	ADP
cet-15445	51	9	active	active	ADJ
cet-15445	51	10	molecules	molecule	NOUN
cet-15445	51	11	and	and	CCONJ
cet-15445	51	12	phospholipids	phospholipid	NOUN
cet-15445	51	13	(	(	PUNCT
cet-15445	51	14	at	at	ADP
cet-15445	51	15	100	100	NUM
cet-15445	51	16	bar	bar	NOUN
cet-15445	51	17	and	and	CCONJ
cet-15445	51	18	40	40	NUM
cet-15445	51	19	°	°	NOUN
cet-15445	51	20	c	c	NOUN
cet-15445	51	21	)	)	PUNCT
cet-15445	51	22	to	to	PART
cet-15445	51	23	form	form	VERB
cet-15445	51	24	liposomes	liposome	NOUN
cet-15445	51	25	,	,	PUNCT
cet-15445	51	26	followed	follow	VERB
cet-15445	51	27	by	by	ADP
cet-15445	51	28	depressurization	depressurization	NOUN
cet-15445	51	29	to	to	PART
cet-15445	51	30	remove	remove	VERB
cet-15445	51	31	co₂-ethanol	co₂-ethanol	NOUN
cet-15445	51	32	mixture	mixture	NOUN
cet-15445	51	33	,	,	PUNCT
cet-15445	51	34	and	and	CCONJ
cet-15445	51	35	drying	dry	VERB
cet-15445	51	36	to	to	PART
cet-15445	51	37	transform	transform	VERB
cet-15445	51	38	the	the	DET
cet-15445	51	39	suspension	suspension	NOUN
cet-15445	51	40	into	into	ADP
cet-15445	51	41	a	a	DET
cet-15445	51	42	powder	powder	NOUN
cet-15445	51	43	.	.	PUNCT
cet-15445	52	1	spaf	spaf	PROPN
cet-15445	52	2	is	be	AUX
cet-15445	52	3	a	a	DET
cet-15445	52	4	scalable	scalable	ADJ
cet-15445	52	5	,	,	PUNCT
cet-15445	52	6	green	green	ADJ
cet-15445	52	7	and	and	CCONJ
cet-15445	52	8	versatile	versatile	ADJ
cet-15445	52	9	process	process	NOUN
cet-15445	52	10	,	,	PUNCT
cet-15445	52	11	compliant	compliant	ADJ
cet-15445	52	12	with	with	ADP
cet-15445	52	13	food	food	NOUN
cet-15445	52	14	-	-	PUNCT
cet-15445	52	15	grade	grade	NOUN
cet-15445	52	16	standards	standard	NOUN
cet-15445	52	17	,	,	PUNCT
cet-15445	52	18	making	make	VERB
cet-15445	52	19	it	it	PRON
cet-15445	52	20	suitable	suitable	ADJ
cet-15445	52	21	for	for	ADP
cet-15445	52	22	nutraceutical	nutraceutical	ADJ
cet-15445	52	23	applications	application	NOUN
cet-15445	52	24	.	.	PUNCT
cet-15445	53	1	in	in	ADP
cet-15445	53	2	detail	detail	NOUN
cet-15445	53	3	,	,	PUNCT
cet-15445	53	4	spaf	spaf	NOUN
cet-15445	53	5	process	process	NOUN
cet-15445	53	6	operates	operate	VERB
cet-15445	53	7	through	through	ADP
cet-15445	53	8	the	the	DET
cet-15445	53	9	following	follow	VERB
cet-15445	53	10	steps	step	NOUN
cet-15445	53	11	:	:	PUNCT
cet-15445	53	12	a	a	DET
cet-15445	53	13	reactor	reactor	NOUN
cet-15445	53	14	is	be	AUX
cet-15445	53	15	filled	fill	VERB
cet-15445	53	16	with	with	ADP
cet-15445	53	17	water	water	NOUN
cet-15445	53	18	,	,	PUNCT
cet-15445	53	19	ethanol	ethanol	NOUN
cet-15445	53	20	,	,	PUNCT
cet-15445	53	21	phospholipids	phospholipid	NOUN
cet-15445	53	22	,	,	PUNCT
cet-15445	53	23	and	and	CCONJ
cet-15445	53	24	the	the	DET
cet-15445	53	25	active	active	ADJ
cet-15445	53	26	compound	compound	NOUN
cet-15445	53	27	.	.	PUNCT
cet-15445	54	1	the	the	DET
cet-15445	54	2	reactor	reactor	NOUN
cet-15445	54	3	is	be	AUX
cet-15445	54	4	sealed	seal	VERB
cet-15445	54	5	and	and	CCONJ
cet-15445	54	6	heated	heat	VERB
cet-15445	54	7	to	to	ADP
cet-15445	54	8	40	40	NUM
cet-15445	55	1	°	°	NOUN
cet-15445	55	2	c	c	NOUN
cet-15445	55	3	at	at	ADP
cet-15445	55	4	1	1	NUM
cet-15445	55	5	bar	bar	NOUN
cet-15445	55	6	.	.	PUNCT
cet-15445	56	1	carbon	carbon	NOUN
cet-15445	56	2	dioxide	dioxide	NOUN
cet-15445	56	3	is	be	AUX
cet-15445	56	4	then	then	ADV
cet-15445	56	5	introduced	introduce	VERB
cet-15445	56	6	in	in	ADP
cet-15445	56	7	the	the	DET
cet-15445	56	8	system	system	NOUN
cet-15445	56	9	up	up	ADP
cet-15445	56	10	to	to	ADP
cet-15445	56	11	a	a	DET
cet-15445	56	12	pressure	pressure	NOUN
cet-15445	56	13	of	of	ADP
cet-15445	56	14	100	100	NUM
cet-15445	56	15	bar	bar	NOUN
cet-15445	56	16	.	.	PUNCT
cet-15445	57	1	this	this	DET
cet-15445	57	2	environment	environment	NOUN
cet-15445	57	3	creates	create	VERB
cet-15445	57	4	a	a	DET
cet-15445	57	5	turbulent	turbulent	ADJ
cet-15445	57	6	system	system	NOUN
cet-15445	57	7	where	where	SCONJ
cet-15445	57	8	water	water	NOUN
cet-15445	57	9	forms	form	NOUN
cet-15445	57	10	droplets	droplet	NOUN
cet-15445	57	11	dispersed	disperse	VERB
cet-15445	57	12	within	within	ADP
cet-15445	57	13	the	the	DET
cet-15445	57	14	carbon	carbon	NOUN
cet-15445	57	15	dioxide	dioxide	NOUN
cet-15445	57	16	.	.	PUNCT
cet-15445	58	1	ethanol	ethanol	NOUN
cet-15445	58	2	,	,	PUNCT
cet-15445	58	3	being	be	AUX
cet-15445	58	4	miscible	miscible	ADJ
cet-15445	58	5	with	with	ADP
cet-15445	58	6	co₂	co₂	NOUN
cet-15445	58	7	,	,	PUNCT
cet-15445	58	8	aids	aid	NOUN
cet-15445	58	9	in	in	ADP
cet-15445	58	10	dissolving	dissolve	VERB
cet-15445	58	11	phospholipids	phospholipid	NOUN
cet-15445	58	12	,	,	PUNCT
cet-15445	58	13	by	by	ADP
cet-15445	58	14	transferring	transfer	VERB
cet-15445	58	15	them	they	PRON
cet-15445	58	16	to	to	ADP
cet-15445	58	17	water	water	NOUN
cet-15445	58	18	molecules	molecule	NOUN
cet-15445	58	19	.	.	PUNCT
cet-15445	59	1	phospholipids	phospholipid	NOUN
cet-15445	59	2	rearrange	rearrange	VERB
cet-15445	59	3	in	in	ADP
cet-15445	59	4	a	a	DET
cet-15445	59	5	turbulent	turbulent	ADJ
cet-15445	59	6	and	and	CCONJ
cet-15445	59	7	aqueous	aqueous	ADJ
cet-15445	59	8	environment	environment	NOUN
cet-15445	59	9	,	,	PUNCT
cet-15445	59	10	thus	thus	ADV
cet-15445	59	11	creating	create	VERB
cet-15445	59	12	liquid	liquid	ADJ
cet-15445	59	13	suspensions	suspension	NOUN
cet-15445	59	14	of	of	ADP
cet-15445	59	15	vesicles	vesicle	NOUN
cet-15445	59	16	.	.	PUNCT
cet-15445	60	1	the	the	DET
cet-15445	60	2	reactor	reactor	NOUN
cet-15445	60	3	is	be	AUX
cet-15445	60	4	depressurized	depressurize	VERB
cet-15445	60	5	,	,	PUNCT
cet-15445	60	6	releasing	release	VERB
cet-15445	60	7	co₂	co₂	NOUN
cet-15445	60	8	and	and	CCONJ
cet-15445	60	9	ethanol	ethanol	NOUN
cet-15445	60	10	.	.	PUNCT
cet-15445	61	1	this	this	DET
cet-15445	61	2	step	step	NOUN
cet-15445	61	3	leaves	leave	VERB
cet-15445	61	4	the	the	DET
cet-15445	61	5	liposomes	liposome	NOUN
cet-15445	61	6	suspended	suspend	VERB
cet-15445	61	7	in	in	ADP
cet-15445	61	8	the	the	DET
cet-15445	61	9	aqueous	aqueous	ADJ
cet-15445	61	10	medium	medium	NOUN
cet-15445	61	11	;	;	PUNCT
cet-15445	61	12	subsequently	subsequently	ADV
cet-15445	61	13	,	,	PUNCT
cet-15445	61	14	drying	dry	VERB
cet-15445	61	15	and	and	CCONJ
cet-15445	61	16	stabilization	stabilization	NOUN
cet-15445	61	17	occurs	occur	VERB
cet-15445	61	18	:	:	PUNCT
cet-15445	61	19	the	the	DET
cet-15445	61	20	aqueous	aqueous	ADJ
cet-15445	61	21	suspension	suspension	NOUN
cet-15445	61	22	is	be	AUX
cet-15445	61	23	subjected	subject	VERB
cet-15445	61	24	to	to	ADP
cet-15445	61	25	freeze	freeze	VERB
cet-15445	61	26	-	-	PUNCT
cet-15445	61	27	drying	dry	VERB
cet-15445	61	28	or	or	CCONJ
cet-15445	61	29	spray	spray	NOUN
cet-15445	61	30	-	-	PUNCT
cet-15445	61	31	drying	dry	VERB
cet-15445	61	32	to	to	PART
cet-15445	61	33	remove	remove	VERB
cet-15445	61	34	residual	residual	ADJ
cet-15445	61	35	water	water	NOUN
cet-15445	61	36	and	and	CCONJ
cet-15445	61	37	convert	convert	VERB
cet-15445	61	38	the	the	DET
cet-15445	61	39	liposomes	liposome	NOUN
cet-15445	61	40	into	into	ADP
cet-15445	61	41	a	a	DET
cet-15445	61	42	stable	stable	ADJ
cet-15445	61	43	powdered	powdered	ADJ
cet-15445	61	44	form	form	NOUN
cet-15445	61	45	.	.	PUNCT
cet-15445	62	1	freeze	freeze	NOUN
cet-15445	62	2	-	-	PUNCT
cet-15445	62	3	drying	dry	VERB
cet-15445	62	4	involves	involve	NOUN
cet-15445	62	5	sublimating	sublimate	VERB
cet-15445	62	6	water	water	NOUN
cet-15445	62	7	under	under	ADP
cet-15445	62	8	vacuum	vacuum	NOUN
cet-15445	62	9	,	,	PUNCT
cet-15445	62	10	while	while	SCONJ
cet-15445	62	11	spray	spray	NOUN
cet-15445	62	12	-	-	PUNCT
cet-15445	62	13	drying	dry	VERB
cet-15445	62	14	uses	use	VERB
cet-15445	62	15	heat	heat	NOUN
cet-15445	62	16	to	to	PART
cet-15445	62	17	evaporate	evaporate	VERB
cet-15445	62	18	water	water	NOUN
cet-15445	62	19	quickly	quickly	ADV
cet-15445	62	20	.	.	PUNCT
cet-15445	63	1	encapsulation	encapsulation	NOUN
cet-15445	63	2	efficiency	efficiency	NOUN
cet-15445	63	3	(	(	PUNCT
cet-15445	63	4	ee	ee	PROPN
cet-15445	63	5	)	)	PUNCT
cet-15445	63	6	,	,	PUNCT
cet-15445	63	7	expressed	express	VERB
cet-15445	63	8	in	in	ADP
cet-15445	63	9	percentage	percentage	NOUN
cet-15445	63	10	,	,	PUNCT
cet-15445	63	11	has	have	AUX
cet-15445	63	12	been	be	AUX
cet-15445	63	13	calculated	calculate	VERB
cet-15445	63	14	as	as	SCONJ
cet-15445	63	15	indicated	indicate	VERB
cet-15445	63	16	in	in	ADP
cet-15445	63	17	eq	eq	NOUN
cet-15445	63	18	.	.	PROPN
cet-15445	64	1	1	1	NUM
cet-15445	64	2	:	:	PUNCT
cet-15445	64	3	𝐸𝐸	𝐸𝐸	PROPN
cet-15445	64	4	,	,	PUNCT
cet-15445	64	5	%	%	NOUN
cet-15445	64	6	=	=	SYM
cet-15445	64	7	𝑎𝑚𝑜𝑢𝑛𝑡	𝑎𝑚𝑜𝑢𝑛𝑡	NOUN
cet-15445	64	8	𝑜𝑓	𝑜𝑓	AUX
cet-15445	64	9	𝑒𝑛𝑡𝑟𝑎𝑝𝑝𝑒𝑑	𝑒𝑛𝑡𝑟𝑎𝑝𝑝𝑒𝑑	VERB
cet-15445	64	10	𝑎𝑐𝑡𝑖𝑣𝑒	𝑎𝑐𝑡𝑖𝑣𝑒	PROPN
cet-15445	64	11	𝑖𝑛𝑔𝑟𝑒𝑑𝑖𝑒𝑛𝑡	𝑖𝑛𝑔𝑟𝑒𝑑𝑖𝑒𝑛𝑡	PROPN
cet-15445	64	12	𝑡𝑜𝑡𝑎𝑙	𝑡𝑜𝑡𝑎𝑙	ADJ
cet-15445	64	13	𝑎𝑚𝑜𝑢𝑛𝑡	𝑎𝑚𝑜𝑢𝑛𝑡	NOUN
cet-15445	64	14	𝑜𝑓	𝑜𝑓	ADP
cet-15445	64	15	𝑎𝑐𝑖𝑡𝑖𝑣𝑒	𝑎𝑐𝑖𝑡𝑖𝑣𝑒	ADJ
cet-15445	64	16	𝑖𝑛𝑔𝑟𝑒𝑑𝑖𝑒𝑛𝑡	𝑖𝑛𝑔𝑟𝑒𝑑𝑖𝑒𝑛𝑡	PROPN
cet-15445	65	1	𝑓𝑒𝑑	𝑓𝑒𝑑	PROPN
cet-15445	65	2	𝑡𝑜	𝑡𝑜	PROPN
cet-15445	65	3	𝑡ℎ𝑒	𝑡ℎ𝑒	VERB
cet-15445	65	4	𝑟𝑒𝑎𝑐𝑡𝑜𝑟	𝑟𝑒𝑎𝑐𝑡𝑜𝑟	PROPN
cet-15445	65	5	∗	∗	NOUN
cet-15445	65	6	100	100	NUM
cet-15445	65	7	(	(	PUNCT
cet-15445	65	8	1	1	NUM
cet-15445	65	9	)	)	PUNCT
cet-15445	65	10	in	in	ADP
cet-15445	65	11	which	which	PRON
cet-15445	65	12	ee	ee	PROPN
cet-15445	65	13	refers	refer	VERB
cet-15445	65	14	to	to	ADP
cet-15445	65	15	the	the	DET
cet-15445	65	16	amount	amount	NOUN
cet-15445	65	17	of	of	ADP
cet-15445	65	18	the	the	DET
cet-15445	65	19	active	active	ADJ
cet-15445	65	20	molecule	molecule	NOUN
cet-15445	65	21	successfully	successfully	ADV
cet-15445	65	22	entrapped	entrap	VERB
cet-15445	65	23	in	in	ADP
cet-15445	65	24	the	the	DET
cet-15445	65	25	inner	inner	ADJ
cet-15445	65	26	core	core	NOUN
cet-15445	65	27	(	(	PUNCT
cet-15445	65	28	for	for	ADP
cet-15445	65	29	hydrophilic	hydrophilic	ADJ
cet-15445	65	30	molecules	molecule	NOUN
cet-15445	65	31	)	)	PUNCT
cet-15445	65	32	and	and	CCONJ
cet-15445	65	33	in	in	ADP
cet-15445	65	34	the	the	DET
cet-15445	65	35	double	double	ADJ
cet-15445	65	36	lipidic	lipidic	ADJ
cet-15445	65	37	layer	layer	NOUN
cet-15445	65	38	for	for	ADP
cet-15445	65	39	the	the	DET
cet-15445	65	40	lipophilic	lipophilic	ADJ
cet-15445	65	41	active	active	ADJ
cet-15445	65	42	molecules	molecule	NOUN
cet-15445	65	43	,	,	PUNCT
cet-15445	65	44	while	while	SCONJ
cet-15445	65	45	the	the	DET
cet-15445	65	46	total	total	ADJ
cet-15445	65	47	amount	amount	NOUN
cet-15445	65	48	of	of	ADP
cet-15445	65	49	active	active	ADJ
cet-15445	65	50	ingredient	ingredient	NOUN
cet-15445	65	51	is	be	AUX
cet-15445	65	52	the	the	DET
cet-15445	65	53	mass	mass	NOUN
cet-15445	65	54	of	of	ADP
cet-15445	65	55	bioactive	bioactive	ADJ
cet-15445	65	56	molecule	molecule	NOUN
cet-15445	65	57	dissolved	dissolve	VERB
cet-15445	65	58	in	in	ADP
cet-15445	65	59	the	the	DET
cet-15445	65	60	preliminary	preliminary	ADJ
cet-15445	65	61	ethanolic	ethanolic	ADJ
cet-15445	65	62	or	or	CCONJ
cet-15445	65	63	aqueous	aqueous	ADJ
cet-15445	65	64	solution	solution	NOUN
cet-15445	65	65	fed	feed	VERB
cet-15445	65	66	to	to	ADP
cet-15445	65	67	the	the	DET
cet-15445	65	68	system	system	NOUN
cet-15445	65	69	(	(	PUNCT
cet-15445	65	70	were	be	AUX
cet-15445	65	71	et	et	PROPN
cet-15445	65	72	al	al	PROPN
cet-15445	65	73	.	.	PROPN
cet-15445	65	74	,	,	PUNCT
cet-15445	65	75	2003	2003	NUM
cet-15445	65	76	)	)	PUNCT
cet-15445	65	77	,	,	PUNCT
cet-15445	65	78	before	before	ADP
cet-15445	65	79	pressurizing	pressurize	VERB
cet-15445	65	80	.	.	PUNCT
cet-15445	66	1	granulometric	granulometric	ADJ
cet-15445	66	2	analysis	analysis	NOUN
cet-15445	66	3	of	of	ADP
cet-15445	66	4	liposome	liposome	NOUN
cet-15445	66	5	samples	sample	NOUN
cet-15445	66	6	were	be	AUX
cet-15445	66	7	performed	perform	VERB
cet-15445	66	8	using	use	VERB
cet-15445	66	9	fiji	fiji	PROPN
cet-15445	66	10	software	software	NOUN
cet-15445	66	11	directly	directly	ADV
cet-15445	66	12	on	on	ADP
cet-15445	66	13	sem	sem	NOUN
cet-15445	66	14	micrographs	micrograph	NOUN
cet-15445	66	15	.	.	PUNCT
cet-15445	67	1	3	3	X
cet-15445	67	2	.	.	NOUN
cet-15445	67	3	results	result	VERB
cet-15445	67	4	the	the	DET
cet-15445	67	5	spaf	spaf	NOUN
cet-15445	67	6	process	process	NOUN
cet-15445	67	7	has	have	AUX
cet-15445	67	8	been	be	AUX
cet-15445	67	9	utilized	utilize	VERB
cet-15445	67	10	for	for	ADP
cet-15445	67	11	various	various	ADJ
cet-15445	67	12	applications	application	NOUN
cet-15445	67	13	in	in	ADP
cet-15445	67	14	the	the	DET
cet-15445	67	15	nutraceutical	nutraceutical	ADJ
cet-15445	67	16	field	field	NOUN
cet-15445	67	17	,	,	PUNCT
cet-15445	67	18	effectively	effectively	ADV
cet-15445	67	19	encapsulating	encapsulate	VERB
cet-15445	67	20	both	both	CCONJ
cet-15445	67	21	hydrophilic	hydrophilic	ADJ
cet-15445	67	22	and	and	CCONJ
cet-15445	67	23	lipophilic	lipophilic	ADJ
cet-15445	67	24	molecules	molecule	NOUN
cet-15445	67	25	.	.	PUNCT
cet-15445	68	1	this	this	DET
cet-15445	68	2	study	study	NOUN
cet-15445	68	3	aims	aim	VERB
cet-15445	68	4	to	to	PART
cet-15445	68	5	demonstrate	demonstrate	VERB
cet-15445	68	6	the	the	DET
cet-15445	68	7	effectiveness	effectiveness	NOUN
cet-15445	68	8	of	of	ADP
cet-15445	68	9	the	the	DET
cet-15445	68	10	spaf	spaf	PROPN
cet-15445	68	11	process	process	NOUN
cet-15445	68	12	for	for	ADP
cet-15445	68	13	encapsulating	encapsulate	VERB
cet-15445	68	14	diverse	diverse	ADJ
cet-15445	68	15	molecules	molecule	NOUN
cet-15445	68	16	,	,	PUNCT
cet-15445	68	17	such	such	ADJ
cet-15445	68	18	as	as	ADP
cet-15445	68	19	ferrous	ferrous	ADJ
cet-15445	68	20	sulfate	sulfate	NOUN
cet-15445	68	21	,	,	PUNCT
cet-15445	68	22	vitamin	vitamin	NOUN
cet-15445	68	23	b12	b12	NOUN
cet-15445	68	24	,	,	PUNCT
cet-15445	68	25	and	and	CCONJ
cet-15445	68	26	melatonin	melatonin	NOUN
cet-15445	68	27	.	.	PUNCT
cet-15445	69	1	figure	figure	VERB
cet-15445	69	2	1	1	NUM
cet-15445	69	3	:	:	PUNCT
cet-15445	69	4	micrograph	micrograph	NOUN
cet-15445	69	5	of	of	ADP
cet-15445	69	6	nanoliposomes	nanoliposome	NOUN
cet-15445	69	7	entrapped	entrap	VERB
cet-15445	69	8	in	in	ADP
cet-15445	69	9	macroscopic	macroscopic	ADJ
cet-15445	69	10	phospholipidic	phospholipidic	ADJ
cet-15445	69	11	aggregates	aggregate	NOUN
cet-15445	69	12	with	with	ADP
cet-15445	69	13	this	this	DET
cet-15445	69	14	process	process	NOUN
cet-15445	69	15	,	,	PUNCT
cet-15445	69	16	it	it	PRON
cet-15445	69	17	is	be	AUX
cet-15445	69	18	possible	possible	ADJ
cet-15445	69	19	to	to	PART
cet-15445	69	20	produce	produce	VERB
cet-15445	69	21	nanoscale	nanoscale	NOUN
cet-15445	69	22	liposomes	liposome	NOUN
cet-15445	69	23	embedded	embed	VERB
cet-15445	69	24	within	within	ADP
cet-15445	69	25	complex	complex	ADJ
cet-15445	69	26	macroscopic	macroscopic	ADJ
cet-15445	69	27	structures	structure	NOUN
cet-15445	69	28	(	(	PUNCT
cet-15445	69	29	see	see	VERB
cet-15445	69	30	figure	figure	NOUN
cet-15445	69	31	1	1	NUM
cet-15445	69	32	)	)	PUNCT
cet-15445	69	33	.	.	PUNCT
cet-15445	70	1	this	this	DET
cet-15445	70	2	capability	capability	NOUN
cet-15445	70	3	highlights	highlight	VERB
cet-15445	70	4	the	the	DET
cet-15445	70	5	versatility	versatility	NOUN
cet-15445	70	6	of	of	ADP
cet-15445	70	7	the	the	DET
cet-15445	70	8	spaf	spaf	NOUN
cet-15445	70	9	(	(	PUNCT
cet-15445	70	10	supercritical	supercritical	ADJ
cet-15445	70	11	assisted	assist	VERB
cet-15445	70	12	phase	phase	NOUN
cet-15445	70	13	separation	separation	NOUN
cet-15445	70	14	)	)	PUNCT
cet-15445	70	15	technique	technique	NOUN
cet-15445	70	16	,	,	PUNCT
cet-15445	70	17	which	which	PRON
cet-15445	70	18	allows	allow	VERB
cet-15445	70	19	for	for	ADP
cet-15445	70	20	the	the	DET
cet-15445	70	21	precise	precise	ADJ
cet-15445	70	22	engineering	engineering	NOUN
cet-15445	70	23	of	of	ADP
cet-15445	70	24	liposome	liposome	NOUN
cet-15445	70	25	size	size	NOUN
cet-15445	70	26	and	and	CCONJ
cet-15445	70	27	distribution	distribution	NOUN
cet-15445	70	28	within	within	ADP
cet-15445	70	29	intricate	intricate	ADJ
cet-15445	70	30	morphological	morphological	ADJ
cet-15445	70	31	frameworks	framework	NOUN
cet-15445	70	32	.	.	PUNCT
cet-15445	71	1	such	such	ADJ
cet-15445	71	2	structures	structure	NOUN
cet-15445	71	3	offer	offer	VERB
cet-15445	71	4	significant	significant	ADJ
cet-15445	71	5	advantages	advantage	NOUN
cet-15445	71	6	in	in	ADP
cet-15445	71	7	applications	application	NOUN
cet-15445	71	8	requiring	require	VERB
cet-15445	71	9	controlled	control	VERB
cet-15445	71	10	release	release	NOUN
cet-15445	71	11	,	,	PUNCT
cet-15445	71	12	targeted	targeted	ADJ
cet-15445	71	13	delivery	delivery	NOUN
cet-15445	71	14	,	,	PUNCT
cet-15445	71	15	or	or	CCONJ
cet-15445	71	16	multifunctional	multifunctional	ADJ
cet-15445	71	17	systems	system	NOUN
cet-15445	71	18	,	,	PUNCT
cet-15445	71	19	where	where	SCONJ
cet-15445	71	20	the	the	DET
cet-15445	71	21	nanoscale	nanoscale	NOUN
cet-15445	71	22	properties	property	NOUN
cet-15445	71	23	of	of	ADP
cet-15445	71	24	liposomes	liposome	NOUN
cet-15445	71	25	synergize	synergize	VERB
cet-15445	71	26	with	with	ADP
cet-15445	71	27	the	the	DET
cet-15445	71	28	structural	structural	ADJ
cet-15445	71	29	complexity	complexity	NOUN
cet-15445	71	30	of	of	ADP
cet-15445	71	31	the	the	DET
cet-15445	71	32	macroscopic	macroscopic	ADJ
cet-15445	71	33	matrix	matrix	NOUN
cet-15445	71	34	.	.	PUNCT
cet-15445	72	1	the	the	DET
cet-15445	72	2	micrograph	micrograph	NOUN
cet-15445	72	3	demonstrates	demonstrate	VERB
cet-15445	72	4	how	how	SCONJ
cet-15445	72	5	these	these	DET
cet-15445	72	6	macroscale	macroscale	NOUN
cet-15445	72	7	structures	structure	NOUN
cet-15445	72	8	maintain	maintain	VERB
cet-15445	72	9	integrity	integrity	NOUN
cet-15445	72	10	while	while	SCONJ
cet-15445	72	11	housing	housing	NOUN
cet-15445	72	12	nanoscale	nanoscale	NOUN
cet-15445	72	13	carriers	carrier	NOUN
cet-15445	72	14	,	,	PUNCT
cet-15445	72	15	ensuring	ensure	VERB
cet-15445	72	16	the	the	DET
cet-15445	72	17	stability	stability	NOUN
cet-15445	72	18	of	of	ADP
cet-15445	72	19	encapsulated	encapsulate	VERB
cet-15445	72	20	agents	agent	NOUN
cet-15445	72	21	and	and	CCONJ
cet-15445	72	22	enhancing	enhance	VERB
cet-15445	72	23	their	their	PRON
cet-15445	72	24	delivery	delivery	NOUN
cet-15445	72	25	efficiency	efficiency	NOUN
cet-15445	72	26	in	in	ADP
cet-15445	72	27	biomedical	biomedical	ADJ
cet-15445	72	28	or	or	CCONJ
cet-15445	72	29	pharmaceutical	pharmaceutical	ADJ
cet-15445	72	30	contexts	context	NOUN
cet-15445	72	31	(	(	PUNCT
cet-15445	72	32	de	de	X
cet-15445	72	33	la	la	X
cet-15445	72	34	torre	torre	PROPN
cet-15445	72	35	&	&	CCONJ
cet-15445	72	36	de	de	PROPN
cet-15445	72	37	pinho	pinho	NOUN
cet-15445	72	38	,	,	PUNCT
cet-15445	72	39	2015	2015	NUM
cet-15445	72	40	)	)	PUNCT
cet-15445	72	41	.	.	PUNCT
cet-15445	73	1	the	the	DET
cet-15445	73	2	ability	ability	NOUN
cet-15445	73	3	to	to	PART
cet-15445	73	4	achieve	achieve	VERB
cet-15445	73	5	this	this	DET
cet-15445	73	6	dual	dual	ADJ
cet-15445	73	7	-	-	PUNCT
cet-15445	73	8	scale	scale	NOUN
cet-15445	73	9	design	design	NOUN
cet-15445	73	10	is	be	AUX
cet-15445	73	11	particularly	particularly	ADV
cet-15445	73	12	promising	promise	VERB
cet-15445	73	13	for	for	ADP
cet-15445	73	14	advanced	advanced	ADJ
cet-15445	73	15	drug	drug	NOUN
cet-15445	73	16	delivery	delivery	NOUN
cet-15445	73	17	systems	system	NOUN
cet-15445	73	18	,	,	PUNCT
cet-15445	73	19	tissue	tissue	NOUN
cet-15445	73	20	engineering	engineering	NOUN
cet-15445	73	21	scaffolds	scaffold	NOUN
cet-15445	73	22	,	,	PUNCT
cet-15445	73	23	or	or	CCONJ
cet-15445	73	24	bioactive	bioactive	VERB
cet-15445	73	25	material	material	NOUN
cet-15445	73	26	development	development	NOUN
cet-15445	73	27	,	,	PUNCT
cet-15445	73	28	where	where	SCONJ
cet-15445	73	29	both	both	DET
cet-15445	73	30	structural	structural	ADJ
cet-15445	73	31	complexity	complexity	NOUN
cet-15445	73	32	and	and	CCONJ
cet-15445	73	33	precise	precise	ADJ
cet-15445	73	34	nanoscale	nanoscale	NOUN
cet-15445	73	35	functionality	functionality	NOUN
cet-15445	73	36	are	be	AUX
cet-15445	73	37	critical	critical	ADJ
cet-15445	73	38	.	.	PUNCT
cet-15445	74	1	1167	1167	NUM
cet-15445	74	2	the	the	DET
cet-15445	74	3	following	follow	VERB
cet-15445	74	4	micrographs	micrograph	NOUN
cet-15445	74	5	(	(	PUNCT
cet-15445	74	6	figures	figure	NOUN
cet-15445	74	7	2	2	NUM
cet-15445	74	8	-	-	SYM
cet-15445	74	9	4	4	NUM
cet-15445	74	10	)	)	PUNCT
cet-15445	74	11	represent	represent	VERB
cet-15445	74	12	studies	study	NOUN
cet-15445	74	13	of	of	ADP
cet-15445	74	14	morphology	morphology	NOUN
cet-15445	74	15	performed	perform	VERB
cet-15445	74	16	on	on	ADP
cet-15445	74	17	liposomes	liposome	NOUN
cet-15445	74	18	produced	produce	VERB
cet-15445	74	19	with	with	ADP
cet-15445	74	20	spaf	spaf	NOUN
cet-15445	74	21	technique	technique	NOUN
cet-15445	74	22	and	and	CCONJ
cet-15445	74	23	loaded	load	VERB
cet-15445	74	24	with	with	ADP
cet-15445	74	25	three	three	NUM
cet-15445	74	26	different	different	ADJ
cet-15445	74	27	molecules	molecule	NOUN
cet-15445	74	28	.	.	PUNCT
cet-15445	75	1	(	(	PUNCT
cet-15445	75	2	a	a	X
cet-15445	75	3	)	)	PUNCT
cet-15445	75	4	(	(	PUNCT
cet-15445	75	5	b	b	X
cet-15445	75	6	)	)	PUNCT
cet-15445	75	7	figure	figure	NOUN
cet-15445	75	8	2	2	NUM
cet-15445	75	9	:	:	PUNCT
cet-15445	75	10	micrograph	micrograph	NOUN
cet-15445	75	11	of	of	ADP
cet-15445	75	12	melatonin	melatonin	NOUN
cet-15445	75	13	loaded	load	VERB
cet-15445	75	14	liposomes	liposome	NOUN
cet-15445	75	15	in	in	ADP
cet-15445	75	16	powder	powder	NOUN
cet-15445	75	17	form	form	NOUN
cet-15445	75	18	observed	observe	VERB
cet-15445	75	19	at	at	ADP
cet-15445	75	20	different	different	ADJ
cet-15445	75	21	magnitude	magnitude	NOUN
cet-15445	75	22	of	of	ADP
cet-15445	75	23	6000x	6000x	NOUN
cet-15445	75	24	(	(	PUNCT
cet-15445	75	25	a	a	NOUN
cet-15445	75	26	)	)	PUNCT
cet-15445	75	27	and	and	CCONJ
cet-15445	75	28	24000	24000	NUM
cet-15445	75	29	(	(	PUNCT
cet-15445	75	30	b	b	NOUN
cet-15445	75	31	)	)	PUNCT
cet-15445	75	32	using	use	VERB
cet-15445	75	33	scanning	scan	VERB
cet-15445	75	34	electron	electron	NOUN
cet-15445	75	35	microscope	microscope	NOUN
cet-15445	75	36	(	(	PUNCT
cet-15445	75	37	a	a	NOUN
cet-15445	75	38	)	)	PUNCT
cet-15445	75	39	(	(	PUNCT
cet-15445	75	40	b	b	X
cet-15445	75	41	)	)	PUNCT
cet-15445	75	42	figure	figure	NOUN
cet-15445	75	43	3	3	NUM
cet-15445	75	44	:	:	PUNCT
cet-15445	75	45	micrograph	micrograph	NOUN
cet-15445	75	46	of	of	ADP
cet-15445	75	47	vitamin	vitamin	NOUN
cet-15445	75	48	b12	b12	NOUN
cet-15445	75	49	loaded	load	VERB
cet-15445	75	50	liposomes	liposome	NOUN
cet-15445	75	51	in	in	ADP
cet-15445	75	52	powder	powder	NOUN
cet-15445	75	53	form	form	NOUN
cet-15445	75	54	observed	observe	VERB
cet-15445	75	55	at	at	ADP
cet-15445	75	56	different	different	ADJ
cet-15445	75	57	magnitude	magnitude	NOUN
cet-15445	75	58	of	of	ADP
cet-15445	75	59	4000x	4000x	NOUN
cet-15445	75	60	(	(	PUNCT
cet-15445	75	61	a	a	NOUN
cet-15445	75	62	)	)	PUNCT
cet-15445	75	63	and	and	CCONJ
cet-15445	75	64	2000	2000	NUM
cet-15445	75	65	(	(	PUNCT
cet-15445	75	66	b	b	NOUN
cet-15445	75	67	)	)	PUNCT
cet-15445	75	68	using	use	VERB
cet-15445	75	69	scanning	scan	VERB
cet-15445	75	70	electron	electron	NOUN
cet-15445	75	71	microscope	microscope	NOUN
cet-15445	75	72	(	(	PUNCT
cet-15445	75	73	a	a	NOUN
cet-15445	75	74	)	)	PUNCT
cet-15445	75	75	(	(	PUNCT
cet-15445	75	76	b	b	X
cet-15445	75	77	)	)	PUNCT
cet-15445	75	78	figure	figure	NOUN
cet-15445	75	79	4	4	NUM
cet-15445	75	80	represents	represent	VERB
cet-15445	75	81	a	a	DET
cet-15445	75	82	micrograph	micrograph	NOUN
cet-15445	75	83	of	of	ADP
cet-15445	75	84	ferrous	ferrous	ADJ
cet-15445	75	85	sulphate	sulphate	NOUN
cet-15445	75	86	loaded	load	VERB
cet-15445	75	87	liposomes	liposome	NOUN
cet-15445	75	88	in	in	ADP
cet-15445	75	89	powder	powder	NOUN
cet-15445	75	90	form	form	NOUN
cet-15445	75	91	observed	observe	VERB
cet-15445	75	92	at	at	ADP
cet-15445	75	93	different	different	ADJ
cet-15445	75	94	magnitudes	magnitude	NOUN
cet-15445	75	95	of	of	ADP
cet-15445	75	96	9500x	9500x	NOUN
cet-15445	75	97	(	(	PUNCT
cet-15445	75	98	a	a	NOUN
cet-15445	75	99	)	)	PUNCT
cet-15445	75	100	and	and	CCONJ
cet-15445	75	101	40500	40500	NUM
cet-15445	75	102	(	(	PUNCT
cet-15445	75	103	b	b	X
cet-15445	75	104	)	)	PUNCT
cet-15445	75	105	using	use	VERB
cet-15445	75	106	scanning	scan	VERB
cet-15445	75	107	electron	electron	NOUN
cet-15445	75	108	microscope	microscope	NOUN
cet-15445	75	109	.	.	PUNCT
cet-15445	76	1	in	in	ADP
cet-15445	76	2	figure	figure	NOUN
cet-15445	76	3	2	2	NUM
cet-15445	76	4	,	,	PUNCT
cet-15445	76	5	melatonin	melatonin	NOUN
cet-15445	76	6	loaded	load	VERB
cet-15445	76	7	liposomes	liposome	NOUN
cet-15445	76	8	are	be	AUX
cet-15445	76	9	reported	report	VERB
cet-15445	76	10	in	in	ADP
cet-15445	76	11	uniform	uniform	NOUN
cet-15445	76	12	and	and	CCONJ
cet-15445	76	13	almost	almost	ADV
cet-15445	76	14	homogeneous	homogeneous	ADJ
cet-15445	76	15	distribution	distribution	NOUN
cet-15445	76	16	,	,	PUNCT
cet-15445	76	17	thus	thus	ADV
cet-15445	76	18	exhibiting	exhibit	VERB
cet-15445	76	19	the	the	DET
cet-15445	76	20	typical	typical	ADJ
cet-15445	76	21	morphology	morphology	NOUN
cet-15445	76	22	of	of	ADP
cet-15445	76	23	agglomerated	agglomerate	VERB
cet-15445	76	24	liposomes	liposome	NOUN
cet-15445	76	25	.	.	PUNCT
cet-15445	77	1	the	the	DET
cet-15445	77	2	phenomena	phenomenon	NOUN
cet-15445	77	3	of	of	ADP
cet-15445	77	4	aggregation	aggregation	NOUN
cet-15445	77	5	are	be	AUX
cet-15445	77	6	typically	typically	ADV
cet-15445	77	7	due	due	ADJ
cet-15445	77	8	to	to	ADP
cet-15445	77	9	the	the	DET
cet-15445	77	10	nature	nature	NOUN
cet-15445	77	11	of	of	ADP
cet-15445	77	12	phospholipids	phospholipid	NOUN
cet-15445	77	13	;	;	PUNCT
cet-15445	77	14	however	however	ADV
cet-15445	77	15	,	,	PUNCT
cet-15445	77	16	this	this	DET
cet-15445	77	17	behavior	behavior	NOUN
cet-15445	77	18	can	can	AUX
cet-15445	77	19	be	be	AUX
cet-15445	77	20	attributed	attribute	VERB
cet-15445	77	21	to	to	ADP
cet-15445	77	22	interactions	interaction	NOUN
cet-15445	77	23	between	between	ADP
cet-15445	77	24	the	the	DET
cet-15445	77	25	liposomes	liposome	NOUN
cet-15445	77	26	during	during	ADP
cet-15445	77	27	drying	dry	VERB
cet-15445	77	28	or	or	CCONJ
cet-15445	77	29	post	post	ADJ
cet-15445	77	30	-	-	ADJ
cet-15445	77	31	processing	processing	ADJ
cet-15445	77	32	stages	stage	NOUN
cet-15445	77	33	.	.	PUNCT
cet-15445	78	1	compared	compare	VERB
cet-15445	78	2	to	to	ADP
cet-15445	78	3	conventional	conventional	ADJ
cet-15445	78	4	methods	method	NOUN
cet-15445	78	5	like	like	ADP
cet-15445	78	6	ethanol	ethanol	NOUN
cet-15445	78	7	injection	injection	NOUN
cet-15445	78	8	or	or	CCONJ
cet-15445	78	9	thin	thin	ADJ
cet-15445	78	10	-	-	PUNCT
cet-15445	78	11	film	film	NOUN
cet-15445	78	12	hydration	hydration	NOUN
cet-15445	78	13	,	,	PUNCT
cet-15445	78	14	especially	especially	ADV
cet-15445	78	15	for	for	ADP
cet-15445	78	16	this	this	DET
cet-15445	78	17	specific	specific	ADJ
cet-15445	78	18	lipophilic	lipophilic	ADJ
cet-15445	78	19	molecule	molecule	NOUN
cet-15445	78	20	,	,	PUNCT
cet-15445	78	21	spaf	spaf	NOUN
cet-15445	78	22	technique	technique	NOUN
cet-15445	78	23	demonstrates	demonstrate	VERB
cet-15445	78	24	an	an	DET
cet-15445	78	25	improved	improved	ADJ
cet-15445	78	26	control	control	NOUN
cet-15445	78	27	1168	1168	NUM
cet-15445	78	28	over	over	ADP
cet-15445	78	29	liposome	liposome	NOUN
cet-15445	78	30	size	size	NOUN
cet-15445	78	31	and	and	CCONJ
cet-15445	78	32	morphology	morphology	NOUN
cet-15445	78	33	.	.	PUNCT
cet-15445	79	1	melatonin	melatonin	PROPN
cet-15445	79	2	,	,	PUNCT
cet-15445	79	3	being	be	AUX
cet-15445	79	4	a	a	DET
cet-15445	79	5	hydrophobic	hydrophobic	NOUN
cet-15445	79	6	molecule	molecule	NOUN
cet-15445	79	7	,	,	PUNCT
cet-15445	79	8	is	be	AUX
cet-15445	79	9	well	well	ADV
cet-15445	79	10	-	-	PUNCT
cet-15445	79	11	suited	suit	VERB
cet-15445	79	12	for	for	ADP
cet-15445	79	13	encapsulation	encapsulation	NOUN
cet-15445	79	14	using	use	VERB
cet-15445	79	15	the	the	DET
cet-15445	79	16	spaf	spaf	PROPN
cet-15445	79	17	technique	technique	NOUN
cet-15445	79	18	,	,	PUNCT
cet-15445	79	19	which	which	PRON
cet-15445	79	20	optimizes	optimize	VERB
cet-15445	79	21	the	the	DET
cet-15445	79	22	partitioning	partitioning	NOUN
cet-15445	79	23	of	of	ADP
cet-15445	79	24	hydrophobic	hydrophobic	NOUN
cet-15445	79	25	substances	substance	NOUN
cet-15445	79	26	into	into	ADP
cet-15445	79	27	the	the	DET
cet-15445	79	28	lipid	lipid	NOUN
cet-15445	79	29	bilayer	bilayer	NOUN
cet-15445	79	30	.	.	PUNCT
cet-15445	80	1	figure	figure	NOUN
cet-15445	80	2	3	3	NUM
cet-15445	80	3	shows	show	VERB
cet-15445	80	4	liposomal	liposomal	ADJ
cet-15445	80	5	morphology	morphology	PROPN
cet-15445	80	6	suggesting	suggest	VERB
cet-15445	80	7	the	the	DET
cet-15445	80	8	formation	formation	NOUN
cet-15445	80	9	of	of	ADP
cet-15445	80	10	large	large	ADJ
cet-15445	80	11	aggregates	aggregate	NOUN
cet-15445	80	12	due	due	ADP
cet-15445	80	13	to	to	ADP
cet-15445	80	14	phospholipid	phospholipid	NOUN
cet-15445	80	15	agglomeration	agglomeration	NOUN
cet-15445	80	16	;	;	PUNCT
cet-15445	80	17	in	in	ADP
cet-15445	80	18	the	the	DET
cet-15445	80	19	inner	inner	ADJ
cet-15445	80	20	sections	section	NOUN
cet-15445	80	21	and	and	CCONJ
cet-15445	80	22	on	on	ADP
cet-15445	80	23	the	the	DET
cet-15445	80	24	outer	outer	ADJ
cet-15445	80	25	surfaces	surface	NOUN
cet-15445	80	26	,	,	PUNCT
cet-15445	80	27	vesicles	vesicle	NOUN
cet-15445	80	28	of	of	ADP
cet-15445	80	29	different	different	ADJ
cet-15445	80	30	shapes	shape	NOUN
cet-15445	80	31	and	and	CCONJ
cet-15445	80	32	roughness	roughness	NOUN
cet-15445	80	33	are	be	AUX
cet-15445	80	34	observed	observe	VERB
cet-15445	80	35	.	.	PUNCT
cet-15445	81	1	moreover	moreover	ADV
cet-15445	81	2	,	,	PUNCT
cet-15445	81	3	the	the	DET
cet-15445	81	4	observed	observed	ADJ
cet-15445	81	5	aggregation	aggregation	NOUN
cet-15445	81	6	could	could	AUX
cet-15445	81	7	be	be	AUX
cet-15445	81	8	due	due	ADJ
cet-15445	81	9	to	to	ADP
cet-15445	81	10	the	the	DET
cet-15445	81	11	absence	absence	NOUN
cet-15445	81	12	or	or	CCONJ
cet-15445	81	13	limited	limited	ADJ
cet-15445	81	14	use	use	NOUN
cet-15445	81	15	of	of	ADP
cet-15445	81	16	surfactants	surfactant	NOUN
cet-15445	81	17	,	,	PUNCT
cet-15445	81	18	but	but	CCONJ
cet-15445	81	19	also	also	ADV
cet-15445	81	20	to	to	ADP
cet-15445	81	21	the	the	DET
cet-15445	81	22	fact	fact	NOUN
cet-15445	81	23	that	that	SCONJ
cet-15445	81	24	vitamin	vitamin	NOUN
cet-15445	81	25	b12	b12	NOUN
cet-15445	81	26	has	have	AUX
cet-15445	81	27	a	a	DET
cet-15445	81	28	larger	large	ADJ
cet-15445	81	29	molecular	molecular	ADJ
cet-15445	81	30	weight	weight	NOUN
cet-15445	81	31	and	and	CCONJ
cet-15445	81	32	requires	require	VERB
cet-15445	81	33	more	more	ADV
cet-15445	81	34	inner	inner	ADJ
cet-15445	81	35	volume	volume	NOUN
cet-15445	81	36	to	to	PART
cet-15445	81	37	be	be	AUX
cet-15445	81	38	entrapped	entrap	VERB
cet-15445	81	39	in	in	ADP
cet-15445	81	40	a	a	DET
cet-15445	81	41	stable	stable	ADJ
cet-15445	81	42	environment	environment	NOUN
cet-15445	81	43	.	.	PUNCT
cet-15445	82	1	as	as	SCONJ
cet-15445	82	2	shown	show	VERB
cet-15445	82	3	in	in	ADP
cet-15445	82	4	figure	figure	NOUN
cet-15445	82	5	4	4	NUM
cet-15445	82	6	,	,	PUNCT
cet-15445	82	7	liposomes	liposome	NOUN
cet-15445	82	8	appear	appear	VERB
cet-15445	82	9	aggregated	aggregate	VERB
cet-15445	82	10	,	,	PUNCT
cet-15445	82	11	possibly	possibly	ADV
cet-15445	82	12	due	due	ADP
cet-15445	82	13	to	to	ADP
cet-15445	82	14	their	their	PRON
cet-15445	82	15	high	high	ADJ
cet-15445	82	16	surface	surface	NOUN
cet-15445	82	17	energy	energy	NOUN
cet-15445	82	18	and	and	CCONJ
cet-15445	82	19	interactions	interaction	NOUN
cet-15445	82	20	between	between	ADP
cet-15445	82	21	particles	particle	NOUN
cet-15445	82	22	during	during	ADP
cet-15445	82	23	or	or	CCONJ
cet-15445	82	24	after	after	ADP
cet-15445	82	25	the	the	DET
cet-15445	82	26	drying	dry	VERB
cet-15445	82	27	process	process	NOUN
cet-15445	82	28	.	.	PUNCT
cet-15445	83	1	surface	surface	NOUN
cet-15445	83	2	roughness	roughness	NOUN
cet-15445	83	3	and	and	CCONJ
cet-15445	83	4	the	the	DET
cet-15445	83	5	presence	presence	NOUN
cet-15445	83	6	of	of	ADP
cet-15445	83	7	a	a	DET
cet-15445	83	8	distinct	distinct	ADJ
cet-15445	83	9	clusterlike	clusterlike	NOUN
cet-15445	83	10	structure	structure	NOUN
cet-15445	83	11	indicate	indicate	VERB
cet-15445	83	12	successful	successful	ADJ
cet-15445	83	13	encapsulation	encapsulation	NOUN
cet-15445	83	14	of	of	ADP
cet-15445	83	15	ferrous	ferrous	ADJ
cet-15445	83	16	sulfate	sulfate	NOUN
cet-15445	83	17	.	.	PUNCT
cet-15445	84	1	regarding	regard	VERB
cet-15445	84	2	structural	structural	ADJ
cet-15445	84	3	integrity	integrity	NOUN
cet-15445	84	4	,	,	PUNCT
cet-15445	84	5	the	the	DET
cet-15445	84	6	cracks	crack	NOUN
cet-15445	84	7	visible	visible	ADJ
cet-15445	84	8	in	in	ADP
cet-15445	84	9	the	the	DET
cet-15445	84	10	substrate	substrate	NOUN
cet-15445	84	11	might	might	AUX
cet-15445	84	12	indicate	indicate	VERB
cet-15445	84	13	a	a	DET
cet-15445	84	14	post	post	ADJ
cet-15445	84	15	-	-	ADJ
cet-15445	84	16	processing	processing	ADJ
cet-15445	84	17	effect	effect	NOUN
cet-15445	84	18	,	,	PUNCT
cet-15445	84	19	potentially	potentially	ADV
cet-15445	84	20	arising	arise	VERB
cet-15445	84	21	during	during	ADP
cet-15445	84	22	the	the	DET
cet-15445	84	23	drying	dry	VERB
cet-15445	84	24	or	or	CCONJ
cet-15445	84	25	freezing	freezing	ADJ
cet-15445	84	26	steps	step	NOUN
cet-15445	84	27	.	.	PUNCT
cet-15445	85	1	this	this	PRON
cet-15445	85	2	does	do	AUX
cet-15445	85	3	not	not	PART
cet-15445	85	4	directly	directly	ADV
cet-15445	85	5	compromise	compromise	VERB
cet-15445	85	6	the	the	DET
cet-15445	85	7	functionality	functionality	NOUN
cet-15445	85	8	;	;	PUNCT
cet-15445	85	9	however	however	ADV
cet-15445	85	10	,	,	PUNCT
cet-15445	85	11	the	the	DET
cet-15445	85	12	clustered	clustered	ADJ
cet-15445	85	13	aggregation	aggregation	NOUN
cet-15445	85	14	could	could	AUX
cet-15445	85	15	indicate	indicate	VERB
cet-15445	85	16	high	high	ADJ
cet-15445	85	17	loading	loading	NOUN
cet-15445	85	18	efficiency	efficiency	NOUN
cet-15445	85	19	,	,	PUNCT
cet-15445	85	20	which	which	PRON
cet-15445	85	21	aligns	align	VERB
cet-15445	85	22	with	with	ADP
cet-15445	85	23	findings	finding	NOUN
cet-15445	85	24	in	in	ADP
cet-15445	85	25	similar	similar	ADJ
cet-15445	85	26	supercritical	supercritical	ADJ
cet-15445	85	27	-	-	PUNCT
cet-15445	85	28	assisted	assist	VERB
cet-15445	85	29	processes	process	NOUN
cet-15445	85	30	.	.	PUNCT
cet-15445	86	1	as	as	ADP
cet-15445	86	2	a	a	DET
cet-15445	86	3	general	general	ADJ
cet-15445	86	4	comment	comment	NOUN
cet-15445	86	5	,	,	PUNCT
cet-15445	86	6	spaf	spaf	NOUN
cet-15445	86	7	process	process	NOUN
cet-15445	86	8	represents	represent	VERB
cet-15445	86	9	a	a	DET
cet-15445	86	10	significant	significant	ADJ
cet-15445	86	11	advancement	advancement	NOUN
cet-15445	86	12	in	in	ADP
cet-15445	86	13	drug	drug	NOUN
cet-15445	86	14	delivery	delivery	NOUN
cet-15445	86	15	system	system	NOUN
cet-15445	86	16	manufacturing	manufacturing	NOUN
cet-15445	86	17	,	,	PUNCT
cet-15445	86	18	enabling	enable	VERB
cet-15445	86	19	the	the	DET
cet-15445	86	20	production	production	NOUN
cet-15445	86	21	of	of	ADP
cet-15445	86	22	a	a	DET
cet-15445	86	23	novel	novel	ADJ
cet-15445	86	24	class	class	NOUN
cet-15445	86	25	of	of	ADP
cet-15445	86	26	systems	system	NOUN
cet-15445	86	27	that	that	PRON
cet-15445	86	28	merge	merge	VERB
cet-15445	86	29	compact	compact	ADJ
cet-15445	86	30	macroscopic	macroscopic	ADJ
cet-15445	86	31	structures	structure	NOUN
cet-15445	86	32	with	with	ADP
cet-15445	86	33	nanometric	nanometric	ADJ
cet-15445	86	34	environments	environment	NOUN
cet-15445	86	35	.	.	PUNCT
cet-15445	87	1	specifically	specifically	ADV
cet-15445	87	2	,	,	PUNCT
cet-15445	87	3	spaf	spaf	NOUN
cet-15445	87	4	technique	technique	NOUN
cet-15445	87	5	facilitates	facilitate	VERB
cet-15445	87	6	the	the	DET
cet-15445	87	7	formation	formation	NOUN
cet-15445	87	8	of	of	ADP
cet-15445	87	9	lipid	lipid	ADJ
cet-15445	87	10	vesicles	vesicle	NOUN
cet-15445	87	11	encapsulated	encapsulate	VERB
cet-15445	87	12	within	within	ADP
cet-15445	87	13	a	a	DET
cet-15445	87	14	macroscopically	macroscopically	ADV
cet-15445	87	15	cohesive	cohesive	ADJ
cet-15445	87	16	matrix	matrix	NOUN
cet-15445	87	17	.	.	PUNCT
cet-15445	88	1	this	this	DET
cet-15445	88	2	duality	duality	NOUN
cet-15445	88	3	is	be	AUX
cet-15445	88	4	evident	evident	ADJ
cet-15445	88	5	in	in	ADP
cet-15445	88	6	the	the	DET
cet-15445	88	7	sem	sem	NOUN
cet-15445	88	8	micrographs	micrograph	NOUN
cet-15445	88	9	,	,	PUNCT
cet-15445	88	10	where	where	SCONJ
cet-15445	88	11	the	the	DET
cet-15445	88	12	compact	compact	ADJ
cet-15445	88	13	surface	surface	NOUN
cet-15445	88	14	morphology	morphology	NOUN
cet-15445	88	15	at	at	ADP
cet-15445	88	16	the	the	DET
cet-15445	88	17	macroscopic	macroscopic	ADJ
cet-15445	88	18	scale	scale	NOUN
cet-15445	88	19	contrasts	contrast	VERB
cet-15445	88	20	with	with	ADP
cet-15445	88	21	the	the	DET
cet-15445	88	22	detailed	detail	VERB
cet-15445	88	23	vesicular	vesicular	ADJ
cet-15445	88	24	nanostructures	nanostructure	NOUN
cet-15445	88	25	observed	observe	VERB
cet-15445	88	26	internally	internally	ADV
cet-15445	88	27	.	.	PUNCT
cet-15445	89	1	the	the	DET
cet-15445	89	2	successful	successful	ADJ
cet-15445	89	3	encapsulation	encapsulation	NOUN
cet-15445	89	4	of	of	ADP
cet-15445	89	5	compounds	compound	NOUN
cet-15445	89	6	like	like	ADP
cet-15445	89	7	melatonin	melatonin	NOUN
cet-15445	89	8	,	,	PUNCT
cet-15445	89	9	vitamin	vitamin	NOUN
cet-15445	89	10	b12	b12	NOUN
cet-15445	89	11	,	,	PUNCT
cet-15445	89	12	and	and	CCONJ
cet-15445	89	13	ferrous	ferrous	ADJ
cet-15445	89	14	sulphate	sulphate	NOUN
cet-15445	89	15	was	be	AUX
cet-15445	89	16	also	also	ADV
cet-15445	89	17	achieved	achieve	VERB
cet-15445	89	18	despite	despite	SCONJ
cet-15445	89	19	the	the	DET
cet-15445	89	20	integration	integration	NOUN
cet-15445	89	21	of	of	ADP
cet-15445	89	22	drying	dry	VERB
cet-15445	89	23	steps	step	NOUN
cet-15445	89	24	to	to	PART
cet-15445	89	25	obtain	obtain	VERB
cet-15445	89	26	the	the	DET
cet-15445	89	27	final	final	ADJ
cet-15445	89	28	powder	powder	NOUN
cet-15445	89	29	,	,	PUNCT
cet-15445	89	30	that	that	PRON
cet-15445	89	31	did	do	AUX
cet-15445	89	32	not	not	PART
cet-15445	89	33	compromise	compromise	VERB
cet-15445	89	34	vesicles	vesicle	NOUN
cet-15445	89	35	stability	stability	NOUN
cet-15445	89	36	.	.	PUNCT
cet-15445	90	1	as	as	ADP
cet-15445	90	2	a	a	DET
cet-15445	90	3	general	general	ADJ
cet-15445	90	4	comment	comment	NOUN
cet-15445	90	5	,	,	PUNCT
cet-15445	90	6	this	this	DET
cet-15445	90	7	structural	structural	ADJ
cet-15445	90	8	duality	duality	NOUN
cet-15445	90	9	highlights	highlight	NOUN
cet-15445	90	10	that	that	SCONJ
cet-15445	90	11	lipid	lipid	NOUN
cet-15445	90	12	vesicles	vesicle	NOUN
cet-15445	90	13	enhance	enhance	VERB
cet-15445	90	14	bioavailability	bioavailability	NOUN
cet-15445	90	15	through	through	ADP
cet-15445	90	16	controlled	control	VERB
cet-15445	90	17	release	release	NOUN
cet-15445	90	18	mechanisms	mechanism	NOUN
cet-15445	90	19	,	,	PUNCT
cet-15445	90	20	while	while	SCONJ
cet-15445	90	21	the	the	DET
cet-15445	90	22	macroscopic	macroscopic	ADJ
cet-15445	90	23	compactness	compactness	NOUN
cet-15445	90	24	facilitates	facilitate	VERB
cet-15445	90	25	handling	handle	VERB
cet-15445	90	26	and	and	CCONJ
cet-15445	90	27	industrial	industrial	ADJ
cet-15445	90	28	scalability	scalability	NOUN
cet-15445	90	29	.	.	PUNCT
cet-15445	91	1	this	this	DET
cet-15445	91	2	innovative	innovative	ADJ
cet-15445	91	3	approach	approach	NOUN
cet-15445	91	4	guarantees	guarantee	VERB
cet-15445	91	5	that	that	SCONJ
cet-15445	91	6	spaf	spaf	PROPN
cet-15445	91	7	offers	offer	VERB
cet-15445	91	8	versatile	versatile	ADJ
cet-15445	91	9	and	and	CCONJ
cet-15445	91	10	highly	highly	ADV
cet-15445	91	11	efficient	efficient	ADJ
cet-15445	91	12	solutions	solution	NOUN
cet-15445	91	13	for	for	ADP
cet-15445	91	14	advanced	advanced	ADJ
cet-15445	91	15	drug	drug	NOUN
cet-15445	91	16	delivery	delivery	NOUN
cet-15445	91	17	applications	application	NOUN
cet-15445	91	18	.	.	PUNCT
cet-15445	92	1	as	as	SCONJ
cet-15445	92	2	reported	report	VERB
cet-15445	92	3	in	in	ADP
cet-15445	92	4	table	table	NOUN
cet-15445	92	5	1	1	NUM
cet-15445	92	6	,	,	PUNCT
cet-15445	92	7	mean	mean	ADJ
cet-15445	92	8	size	size	NOUN
cet-15445	92	9	of	of	ADP
cet-15445	92	10	melatonin	melatonin	NOUN
cet-15445	92	11	loaded	load	VERB
cet-15445	92	12	liposomes	liposome	NOUN
cet-15445	92	13	is	be	AUX
cet-15445	92	14	238	238	NUM
cet-15445	92	15	±	±	NUM
cet-15445	92	16	79	79	NUM
cet-15445	92	17	nm	nm	NOUN
cet-15445	92	18	,	,	PUNCT
cet-15445	92	19	with	with	ADP
cet-15445	92	20	a	a	DET
cet-15445	92	21	very	very	ADV
cet-15445	92	22	high	high	ADJ
cet-15445	92	23	encapsulation	encapsulation	NOUN
cet-15445	92	24	efficiency	efficiency	NOUN
cet-15445	92	25	.	.	PUNCT
cet-15445	93	1	this	this	DET
cet-15445	93	2	molecule	molecule	NOUN
cet-15445	93	3	,	,	PUNCT
cet-15445	93	4	being	be	AUX
cet-15445	93	5	relatively	relatively	ADV
cet-15445	93	6	small	small	ADJ
cet-15445	93	7	and	and	CCONJ
cet-15445	93	8	lipophilic	lipophilic	ADJ
cet-15445	93	9	,	,	PUNCT
cet-15445	93	10	integrates	integrate	NOUN
cet-15445	93	11	easily	easily	ADV
cet-15445	93	12	into	into	ADP
cet-15445	93	13	the	the	DET
cet-15445	93	14	liposomal	liposomal	ADJ
cet-15445	93	15	structure	structure	NOUN
cet-15445	93	16	,	,	PUNCT
cet-15445	93	17	explaining	explain	VERB
cet-15445	93	18	its	its	PRON
cet-15445	93	19	high	high	ADJ
cet-15445	93	20	efficiency	efficiency	NOUN
cet-15445	93	21	and	and	CCONJ
cet-15445	93	22	compact	compact	ADJ
cet-15445	93	23	size	size	NOUN
cet-15445	93	24	.	.	PUNCT
cet-15445	94	1	vitamin	vitamin	NOUN
cet-15445	94	2	b12	b12	NOUN
cet-15445	94	3	loaded	load	VERB
cet-15445	94	4	liposomes	liposome	NOUN
cet-15445	94	5	exhibit	exhibit	VERB
cet-15445	94	6	significantly	significantly	ADV
cet-15445	94	7	larger	large	ADJ
cet-15445	94	8	dimensions	dimension	NOUN
cet-15445	94	9	(	(	PUNCT
cet-15445	94	10	1198	1198	NUM
cet-15445	94	11	±	±	NUM
cet-15445	94	12	372	372	NUM
cet-15445	94	13	nm	nm	NOUN
cet-15445	94	14	)	)	PUNCT
cet-15445	94	15	with	with	ADP
cet-15445	94	16	a	a	DET
cet-15445	94	17	slightly	slightly	ADV
cet-15445	94	18	lower	low	ADJ
cet-15445	94	19	encapsulation	encapsulation	NOUN
cet-15445	94	20	efficiency	efficiency	NOUN
cet-15445	94	21	(	(	PUNCT
cet-15445	94	22	91	91	NUM
cet-15445	94	23	±	±	NUM
cet-15445	94	24	5	5	NUM
cet-15445	94	25	%	%	NOUN
cet-15445	94	26	)	)	PUNCT
cet-15445	94	27	.	.	PUNCT
cet-15445	95	1	the	the	DET
cet-15445	95	2	larger	large	ADJ
cet-15445	95	3	size	size	NOUN
cet-15445	95	4	can	can	AUX
cet-15445	95	5	be	be	AUX
cet-15445	95	6	attributed	attribute	VERB
cet-15445	95	7	to	to	ADP
cet-15445	95	8	the	the	DET
cet-15445	95	9	hydrophilic	hydrophilic	ADJ
cet-15445	95	10	nature	nature	NOUN
cet-15445	95	11	and	and	CCONJ
cet-15445	95	12	higher	high	ADJ
cet-15445	95	13	molecular	molecular	ADJ
cet-15445	95	14	weight	weight	NOUN
cet-15445	95	15	of	of	ADP
cet-15445	95	16	vitamin	vitamin	NOUN
cet-15445	95	17	b12	b12	NOUN
cet-15445	95	18	,	,	PUNCT
cet-15445	95	19	which	which	PRON
cet-15445	95	20	requires	require	VERB
cet-15445	95	21	a	a	DET
cet-15445	95	22	broader	broad	ADJ
cet-15445	95	23	lipid	lipid	NOUN
cet-15445	95	24	structure	structure	NOUN
cet-15445	95	25	for	for	ADP
cet-15445	95	26	inclusion	inclusion	NOUN
cet-15445	95	27	.	.	PUNCT
cet-15445	96	1	ferrous	ferrous	ADJ
cet-15445	96	2	sulfate	sulfate	NOUN
cet-15445	96	3	loaded	load	VERB
cet-15445	96	4	liposomes	liposome	NOUN
cet-15445	96	5	are	be	AUX
cet-15445	96	6	the	the	DET
cet-15445	96	7	smallest	small	ADJ
cet-15445	96	8	ones	one	NOUN
cet-15445	96	9	(	(	PUNCT
cet-15445	96	10	35	35	NUM
cet-15445	96	11	±	±	NUM
cet-15445	96	12	11	11	NUM
cet-15445	96	13	nm	nm	NOUN
cet-15445	96	14	)	)	PUNCT
cet-15445	96	15	,	,	PUNCT
cet-15445	96	16	yet	yet	CCONJ
cet-15445	96	17	they	they	PRON
cet-15445	96	18	maintain	maintain	VERB
cet-15445	96	19	a	a	DET
cet-15445	96	20	high	high	ADJ
cet-15445	96	21	encapsulation	encapsulation	NOUN
cet-15445	96	22	efficiency	efficiency	NOUN
cet-15445	96	23	(	(	PUNCT
cet-15445	96	24	92	92	NUM
cet-15445	96	25	±	±	NUM
cet-15445	96	26	2	2	NUM
cet-15445	96	27	%	%	NOUN
cet-15445	96	28	)	)	PUNCT
cet-15445	96	29	.	.	PUNCT
cet-15445	97	1	the	the	DET
cet-15445	97	2	reduced	reduced	ADJ
cet-15445	97	3	size	size	NOUN
cet-15445	97	4	could	could	AUX
cet-15445	97	5	be	be	AUX
cet-15445	97	6	due	due	ADJ
cet-15445	97	7	to	to	ADP
cet-15445	97	8	the	the	DET
cet-15445	97	9	ionic	ionic	ADJ
cet-15445	97	10	nature	nature	NOUN
cet-15445	97	11	of	of	ADP
cet-15445	97	12	ferrous	ferrous	ADJ
cet-15445	97	13	sulfate	sulfate	NOUN
cet-15445	97	14	and	and	CCONJ
cet-15445	97	15	its	its	PRON
cet-15445	97	16	easy	easy	ADJ
cet-15445	97	17	interaction	interaction	NOUN
cet-15445	97	18	with	with	ADP
cet-15445	97	19	the	the	DET
cet-15445	97	20	lipid	lipid	NOUN
cet-15445	97	21	matrix	matrix	NOUN
cet-15445	97	22	,	,	PUNCT
cet-15445	97	23	enabling	enable	VERB
cet-15445	97	24	a	a	DET
cet-15445	97	25	more	more	ADV
cet-15445	97	26	compact	compact	ADJ
cet-15445	97	27	organization	organization	NOUN
cet-15445	97	28	.	.	PUNCT
cet-15445	98	1	table	table	NOUN
cet-15445	98	2	2	2	NUM
cet-15445	98	3	highlights	highlight	NOUN
cet-15445	98	4	the	the	DET
cet-15445	98	5	stability	stability	NOUN
cet-15445	98	6	of	of	ADP
cet-15445	98	7	liposomes	liposome	NOUN
cet-15445	98	8	and	and	CCONJ
cet-15445	98	9	the	the	DET
cet-15445	98	10	absence	absence	NOUN
cet-15445	98	11	of	of	ADP
cet-15445	98	12	chemical	chemical	ADJ
cet-15445	98	13	contaminants	contaminant	NOUN
cet-15445	98	14	.	.	PUNCT
cet-15445	99	1	stability	stability	NOUN
cet-15445	99	2	varies	vary	VERB
cet-15445	99	3	across	across	ADP
cet-15445	99	4	molecules	molecule	NOUN
cet-15445	99	5	:	:	PUNCT
cet-15445	99	6	ferrous	ferrous	ADJ
cet-15445	99	7	sulphate	sulphate	NOUN
cet-15445	99	8	shows	show	VERB
cet-15445	99	9	the	the	DET
cet-15445	99	10	highest	high	ADJ
cet-15445	99	11	stability	stability	NOUN
cet-15445	99	12	(	(	PUNCT
cet-15445	99	13	820	820	NUM
cet-15445	99	14	days	day	NOUN
cet-15445	99	15	)	)	PUNCT
cet-15445	99	16	,	,	PUNCT
cet-15445	99	17	likely	likely	ADJ
cet-15445	99	18	due	due	ADP
cet-15445	99	19	to	to	ADP
cet-15445	99	20	its	its	PRON
cet-15445	99	21	simple	simple	ADJ
cet-15445	99	22	chemical	chemical	NOUN
cet-15445	99	23	structure	structure	NOUN
cet-15445	99	24	and	and	CCONJ
cet-15445	99	25	compatibility	compatibility	NOUN
cet-15445	99	26	with	with	ADP
cet-15445	99	27	the	the	DET
cet-15445	99	28	lipid	lipid	NOUN
cet-15445	99	29	matrix	matrix	NOUN
cet-15445	99	30	,	,	PUNCT
cet-15445	99	31	while	while	SCONJ
cet-15445	99	32	melatonin	melatonin	NOUN
cet-15445	99	33	and	and	CCONJ
cet-15445	99	34	vitamin	vitamin	NOUN
cet-15445	99	35	b12	b12	NOUN
cet-15445	99	36	have	have	VERB
cet-15445	99	37	stability	stability	NOUN
cet-15445	99	38	of	of	ADP
cet-15445	99	39	760	760	NUM
cet-15445	99	40	and	and	CCONJ
cet-15445	99	41	540	540	NUM
cet-15445	99	42	days	day	NOUN
cet-15445	99	43	,	,	PUNCT
cet-15445	99	44	respectively	respectively	ADV
cet-15445	99	45	,	,	PUNCT
cet-15445	99	46	with	with	ADP
cet-15445	99	47	the	the	DET
cet-15445	99	48	latter	latter	ADJ
cet-15445	99	49	influenced	influence	VERB
cet-15445	99	50	by	by	ADP
cet-15445	99	51	its	its	PRON
cet-15445	99	52	chemical	chemical	NOUN
cet-15445	99	53	complexity	complexity	NOUN
cet-15445	99	54	.	.	PUNCT
cet-15445	100	1	additionally	additionally	ADV
cet-15445	100	2	,	,	PUNCT
cet-15445	100	3	no	no	DET
cet-15445	100	4	heavy	heavy	ADJ
cet-15445	100	5	metals	metal	NOUN
cet-15445	100	6	or	or	CCONJ
cet-15445	100	7	pesticides	pesticide	NOUN
cet-15445	100	8	were	be	AUX
cet-15445	100	9	detected	detect	VERB
cet-15445	100	10	in	in	ADP
cet-15445	100	11	any	any	DET
cet-15445	100	12	sample	sample	NOUN
cet-15445	100	13	,	,	PUNCT
cet-15445	100	14	confirming	confirm	VERB
cet-15445	100	15	the	the	DET
cet-15445	100	16	high	high	ADJ
cet-15445	100	17	purity	purity	NOUN
cet-15445	100	18	of	of	ADP
cet-15445	100	19	liposomes	liposome	NOUN
cet-15445	100	20	produced	produce	VERB
cet-15445	100	21	with	with	ADP
cet-15445	100	22	the	the	DET
cet-15445	100	23	spaf	spaf	PROPN
cet-15445	100	24	technique	technique	NOUN
cet-15445	100	25	.	.	PUNCT
cet-15445	101	1	table	table	NOUN
cet-15445	101	2	1	1	NUM
cet-15445	101	3	:	:	PUNCT
cet-15445	101	4	mean	mean	ADJ
cet-15445	101	5	size	size	NOUN
cet-15445	101	6	and	and	CCONJ
cet-15445	101	7	encapsulation	encapsulation	NOUN
cet-15445	101	8	efficiency	efficiency	NOUN
cet-15445	101	9	of	of	ADP
cet-15445	101	10	liposomes	liposome	NOUN
cet-15445	101	11	produced	produce	VERB
cet-15445	101	12	using	use	VERB
cet-15445	101	13	spaf	spaf	NOUN
cet-15445	101	14	technique	technique	NOUN
cet-15445	101	15	molecule	molecule	NOUN
cet-15445	101	16	molecule	molecule	NOUN
cet-15445	101	17	/	/	SYM
cet-15445	101	18	lipids	lipid	NOUN
cet-15445	101	19	,	,	PUNCT
cet-15445	102	1	%	%	NOUN
cet-15445	102	2	mean	mean	NOUN
cet-15445	102	3	dimensions	dimension	NOUN
cet-15445	102	4	,	,	PUNCT
cet-15445	102	5	nm	nm	PRON
cet-15445	102	6	±	±	NUM
cet-15445	102	7	sd	sd	ADP
cet-15445	102	8	encapsulation	encapsulation	NOUN
cet-15445	102	9	efficiency	efficiency	NOUN
cet-15445	102	10	(	(	PUNCT
cet-15445	102	11	ee	ee	PROPN
cet-15445	102	12	)	)	PUNCT
cet-15445	102	13	,	,	PUNCT
cet-15445	102	14	%	%	INTJ
cet-15445	103	1	±	±	NUM
cet-15445	103	2	sd	sd	ADP
cet-15445	103	3	melatonin	melatonin	NOUN
cet-15445	103	4	1:1	1:1	NUM
cet-15445	103	5	238	238	NUM
cet-15445	103	6	±	±	NUM
cet-15445	103	7	79	79	NUM
cet-15445	103	8	94	94	NUM
cet-15445	103	9	±	±	NUM
cet-15445	103	10	3	3	NUM
cet-15445	103	11	vitamin	vitamin	NOUN
cet-15445	103	12	b12	b12	NOUN
cet-15445	103	13	1:1	1:1	NUM
cet-15445	103	14	1198	1198	NUM
cet-15445	103	15	±	±	NUM
cet-15445	103	16	372	372	NUM
cet-15445	103	17	91	91	NUM
cet-15445	103	18	±	±	NUM
cet-15445	103	19	5	5	NUM
cet-15445	103	20	ferrous	ferrous	ADJ
cet-15445	103	21	sulphate	sulphate	NOUN
cet-15445	103	22	1:1	1:1	NUM
cet-15445	103	23	35	35	NUM
cet-15445	103	24	±	±	NUM
cet-15445	103	25	11	11	NUM
cet-15445	103	26	92	92	NUM
cet-15445	103	27	±	±	NUM
cet-15445	103	28	2	2	NUM
cet-15445	103	29	table	table	NOUN
cet-15445	103	30	2	2	NUM
cet-15445	103	31	:	:	PUNCT
cet-15445	103	32	stability	stability	NOUN
cet-15445	103	33	of	of	ADP
cet-15445	103	34	liposomes	liposome	NOUN
cet-15445	103	35	produced	produce	VERB
cet-15445	103	36	using	use	VERB
cet-15445	103	37	spaf	spaf	PROPN
cet-15445	103	38	technique	technique	NOUN
cet-15445	103	39	molecule	molecule	NOUN
cet-15445	103	40	stability	stability	NOUN
cet-15445	103	41	(	(	PUNCT
cet-15445	103	42	s	s	NOUN
cet-15445	103	43	)	)	PUNCT
cet-15445	103	44	,	,	PUNCT
cet-15445	103	45	days	day	NOUN
cet-15445	103	46	heavy	heavy	ADJ
cet-15445	103	47	metals	metal	NOUN
cet-15445	103	48	(	(	PUNCT
cet-15445	103	49	hm	hm	INTJ
cet-15445	103	50	)	)	PUNCT
cet-15445	103	51	,	,	PUNCT
cet-15445	103	52	ppm	ppm	VERB
cet-15445	103	53	pesticides	pesticide	NOUN
cet-15445	103	54	(	(	PUNCT
cet-15445	103	55	p	p	NOUN
cet-15445	103	56	)	)	PUNCT
cet-15445	103	57	,	,	PUNCT
cet-15445	103	58	ppm	ppm	NOUN
cet-15445	103	59	melatonin	melatonin	NOUN
cet-15445	104	1	760	760	NUM
cet-15445	104	2	n.d	n.d	PROPN
cet-15445	104	3	.	.	PROPN
cet-15445	104	4	n.d	n.d	PROPN
cet-15445	104	5	.	.	PROPN
cet-15445	104	6	vitamin	vitamin	NOUN
cet-15445	104	7	b12	b12	NOUN
cet-15445	104	8	540	540	NUM
cet-15445	104	9	n.d	n.d	PROPN
cet-15445	104	10	.	.	PROPN
cet-15445	104	11	n.d	n.d	PROPN
cet-15445	104	12	.	.	PROPN
cet-15445	104	13	ferrous	ferrous	ADJ
cet-15445	104	14	sulphate	sulphate	NOUN
cet-15445	104	15	820	820	NUM
cet-15445	104	16	n.d	n.d	PROPN
cet-15445	104	17	.	.	PROPN
cet-15445	104	18	n.d	n.d	PROPN
cet-15445	104	19	.	.	PROPN
cet-15445	104	20	4	4	NUM
cet-15445	104	21	.	.	PUNCT
cet-15445	104	22	conclusions	conclusion	NOUN
cet-15445	104	23	compared	compare	VERB
cet-15445	104	24	to	to	ADP
cet-15445	104	25	traditional	traditional	ADJ
cet-15445	104	26	thin	thin	ADJ
cet-15445	104	27	-	-	PUNCT
cet-15445	104	28	film	film	NOUN
cet-15445	104	29	hydration	hydration	NOUN
cet-15445	104	30	or	or	CCONJ
cet-15445	104	31	ethanol	ethanol	NOUN
cet-15445	104	32	injection	injection	NOUN
cet-15445	104	33	methods	method	NOUN
cet-15445	104	34	,	,	PUNCT
cet-15445	104	35	the	the	DET
cet-15445	104	36	spaf	spaf	NOUN
cet-15445	104	37	technique	technique	NOUN
cet-15445	104	38	demonstrates	demonstrate	VERB
cet-15445	104	39	superior	superior	ADJ
cet-15445	104	40	performance	performance	NOUN
cet-15445	104	41	by	by	ADP
cet-15445	104	42	yielding	yield	VERB
cet-15445	104	43	particles	particle	NOUN
cet-15445	104	44	with	with	ADP
cet-15445	104	45	enhanced	enhanced	ADJ
cet-15445	104	46	encapsulation	encapsulation	NOUN
cet-15445	104	47	efficiency	efficiency	NOUN
cet-15445	104	48	and	and	CCONJ
cet-15445	104	49	improved	improved	ADJ
cet-15445	104	50	control	control	NOUN
cet-15445	104	51	over	over	ADP
cet-15445	104	52	particle	particle	NOUN
cet-15445	104	53	morphology	morphology	NOUN
cet-15445	104	54	.	.	PUNCT
cet-15445	105	1	in	in	ADP
cet-15445	105	2	details	detail	NOUN
cet-15445	105	3	,	,	PUNCT
cet-15445	105	4	this	this	DET
cet-15445	105	5	process	process	NOUN
cet-15445	105	6	overcomes	overcome	VERB
cet-15445	105	7	common	common	ADJ
cet-15445	105	8	drawbacks	drawback	NOUN
cet-15445	105	9	because	because	SCONJ
cet-15445	105	10	it	it	PRON
cet-15445	105	11	eliminates	eliminate	VERB
cet-15445	105	12	residual	residual	ADJ
cet-15445	105	13	solvents	solvent	NOUN
cet-15445	105	14	,	,	PUNCT
cet-15445	105	15	ensuring	ensure	VERB
cet-15445	105	16	higher	high	ADJ
cet-15445	105	17	product	product	NOUN
cet-15445	105	18	safety	safety	NOUN
cet-15445	105	19	than	than	ADP
cet-15445	105	20	conventional	conventional	ADJ
cet-15445	105	21	methods	method	NOUN
cet-15445	105	22	.	.	PUNCT
cet-15445	106	1	additionally	additionally	ADV
cet-15445	106	2	,	,	PUNCT
cet-15445	106	3	it	it	PRON
cet-15445	106	4	enhances	enhance	VERB
cet-15445	106	5	encapsulation	encapsulation	NOUN
cet-15445	106	6	1169	1169	NUM
cet-15445	106	7	efficiency	efficiency	NOUN
cet-15445	106	8	(	(	PUNCT
cet-15445	106	9	up	up	ADP
cet-15445	106	10	to	to	PART
cet-15445	106	11	94	94	NUM
cet-15445	106	12	%	%	NOUN
cet-15445	106	13	)	)	PUNCT
cet-15445	106	14	and	and	CCONJ
cet-15445	106	15	enables	enable	VERB
cet-15445	106	16	long	long	ADJ
cet-15445	106	17	-	-	PUNCT
cet-15445	106	18	term	term	NOUN
cet-15445	106	19	stability	stability	NOUN
cet-15445	106	20	of	of	ADP
cet-15445	106	21	liposomes	liposome	NOUN
cet-15445	106	22	in	in	ADP
cet-15445	106	23	a	a	DET
cet-15445	106	24	dry	dry	ADJ
cet-15445	106	25	powder	powder	NOUN
cet-15445	106	26	form	form	NOUN
cet-15445	106	27	,	,	PUNCT
cet-15445	106	28	overcoming	overcome	VERB
cet-15445	106	29	storage	storage	NOUN
cet-15445	106	30	and	and	CCONJ
cet-15445	106	31	degradation	degradation	NOUN
cet-15445	106	32	issues	issue	NOUN
cet-15445	106	33	associated	associate	VERB
cet-15445	106	34	with	with	ADP
cet-15445	106	35	aqueous	aqueous	ADJ
cet-15445	106	36	suspensions	suspension	NOUN
cet-15445	106	37	(	(	PUNCT
cet-15445	106	38	sofia	sofia	NOUN
cet-15445	106	39	et	et	PROPN
cet-15445	106	40	al	al	PROPN
cet-15445	106	41	,	,	PUNCT
cet-15445	106	42	2025	2025	NUM
cet-15445	106	43	)	)	PUNCT
cet-15445	106	44	.	.	PUNCT
cet-15445	107	1	sem	sem	NOUN
cet-15445	107	2	micrographs	micrograph	NOUN
cet-15445	107	3	from	from	ADP
cet-15445	107	4	similar	similar	ADJ
cet-15445	107	5	studies	study	NOUN
cet-15445	107	6	consistently	consistently	ADV
cet-15445	107	7	highlight	highlight	VERB
cet-15445	107	8	the	the	DET
cet-15445	107	9	rough	rough	ADJ
cet-15445	107	10	,	,	PUNCT
cet-15445	107	11	porous	porous	ADJ
cet-15445	107	12	structures	structure	NOUN
cet-15445	107	13	as	as	ADP
cet-15445	107	14	distinctive	distinctive	ADJ
cet-15445	107	15	features	feature	NOUN
cet-15445	107	16	of	of	ADP
cet-15445	107	17	liposomes	liposome	NOUN
cet-15445	107	18	produced	produce	VERB
cet-15445	107	19	using	use	VERB
cet-15445	107	20	spaf	spaf	NOUN
cet-15445	107	21	,	,	PUNCT
cet-15445	107	22	particularly	particularly	ADV
cet-15445	107	23	when	when	SCONJ
cet-15445	107	24	encapsulating	encapsulate	VERB
cet-15445	107	25	hydrophilic	hydrophilic	ADJ
cet-15445	107	26	or	or	CCONJ
cet-15445	107	27	ionic	ionic	ADJ
cet-15445	107	28	compounds	compound	NOUN
cet-15445	107	29	.	.	PUNCT
cet-15445	108	1	additionally	additionally	ADV
cet-15445	108	2	,	,	PUNCT
cet-15445	108	3	aggregation	aggregation	NOUN
cet-15445	108	4	is	be	AUX
cet-15445	108	5	commonly	commonly	ADV
cet-15445	108	6	observed	observe	VERB
cet-15445	108	7	in	in	ADP
cet-15445	108	8	samples	sample	NOUN
cet-15445	108	9	processed	process	VERB
cet-15445	108	10	with	with	ADP
cet-15445	108	11	minimal	minimal	ADJ
cet-15445	108	12	surfactant	surfactant	NOUN
cet-15445	108	13	or	or	CCONJ
cet-15445	108	14	stabilizing	stabilize	VERB
cet-15445	108	15	agents	agent	NOUN
cet-15445	108	16	,	,	PUNCT
cet-15445	108	17	which	which	PRON
cet-15445	108	18	could	could	AUX
cet-15445	108	19	explain	explain	VERB
cet-15445	108	20	the	the	DET
cet-15445	108	21	clustering	clustering	NOUN
cet-15445	108	22	observed	observe	VERB
cet-15445	108	23	in	in	ADP
cet-15445	108	24	the	the	DET
cet-15445	108	25	current	current	ADJ
cet-15445	108	26	sample	sample	NOUN
cet-15445	108	27	.	.	PUNCT
cet-15445	109	1	based	base	VERB
cet-15445	109	2	on	on	ADP
cet-15445	109	3	morphology	morphology	NOUN
cet-15445	109	4	,	,	PUNCT
cet-15445	109	5	these	these	DET
cet-15445	109	6	liposomes	liposome	NOUN
cet-15445	109	7	could	could	AUX
cet-15445	109	8	be	be	AUX
cet-15445	109	9	suitable	suitable	ADJ
cet-15445	109	10	for	for	ADP
cet-15445	109	11	controlled	control	VERB
cet-15445	109	12	release	release	NOUN
cet-15445	109	13	applications	application	NOUN
cet-15445	109	14	and	and	CCONJ
cet-15445	109	15	successful	successful	ADJ
cet-15445	109	16	nutraceutical	nutraceutical	ADJ
cet-15445	109	17	purposes	purpose	NOUN
cet-15445	109	18	.	.	PUNCT
cet-15445	110	1	acknowledgements	acknowledgement	NOUN
cet-15445	110	2	the	the	DET
cet-15445	110	3	authors	author	NOUN
cet-15445	110	4	would	would	AUX
cet-15445	110	5	like	like	VERB
cet-15445	110	6	to	to	PART
cet-15445	110	7	express	express	VERB
cet-15445	110	8	their	their	PRON
cet-15445	110	9	gratitude	gratitude	NOUN
cet-15445	110	10	to	to	ADP
cet-15445	110	11	the	the	DET
cet-15445	110	12	entire	entire	ADJ
cet-15445	110	13	team	team	NOUN
cet-15445	110	14	of	of	ADP
cet-15445	110	15	iodo	iodo	NOUN
cet-15445	110	16	;	;	PUNCT
cet-15445	110	17	in	in	ADP
cet-15445	110	18	particular	particular	ADJ
cet-15445	110	19	,	,	PUNCT
cet-15445	110	20	special	special	ADJ
cet-15445	110	21	thanks	thank	NOUN
cet-15445	110	22	go	go	VERB
cet-15445	110	23	to	to	ADP
cet-15445	110	24	alessandro	alessandro	PROPN
cet-15445	110	25	liuzzi	liuzzi	PROPN
cet-15445	110	26	,	,	PUNCT
cet-15445	110	27	michela	michela	PROPN
cet-15445	110	28	ielpo	ielpo	PROPN
cet-15445	110	29	,	,	PUNCT
cet-15445	110	30	stefania	stefania	PROPN
cet-15445	110	31	ferrigno	ferrigno	PROPN
cet-15445	110	32	,	,	PUNCT
cet-15445	110	33	and	and	CCONJ
cet-15445	110	34	damiana	damiana	PROPN
cet-15445	110	35	pisaturo	pisaturo	PROPN
cet-15445	110	36	for	for	ADP
cet-15445	110	37	their	their	PRON
cet-15445	110	38	dedication	dedication	NOUN
cet-15445	110	39	,	,	PUNCT
cet-15445	110	40	expertise	expertise	NOUN
cet-15445	110	41	,	,	PUNCT
cet-15445	110	42	and	and	CCONJ
cet-15445	110	43	collaborative	collaborative	ADJ
cet-15445	110	44	efforts	effort	NOUN
cet-15445	110	45	,	,	PUNCT
cet-15445	110	46	which	which	PRON
cet-15445	110	47	have	have	AUX
cet-15445	110	48	been	be	AUX
cet-15445	110	49	instrumental	instrumental	ADJ
cet-15445	110	50	in	in	ADP
cet-15445	110	51	the	the	DET
cet-15445	110	52	successful	successful	ADJ
cet-15445	110	53	completion	completion	NOUN
cet-15445	110	54	of	of	ADP
cet-15445	110	55	this	this	DET
cet-15445	110	56	study	study	NOUN
cet-15445	110	57	.	.	PUNCT
cet-15445	111	1	references	reference	NOUN
cet-15445	111	2	de	de	X
cet-15445	111	3	la	la	PROPN
cet-15445	111	4	torre	torre	PROPN
cet-15445	111	5	l.	l.	PROPN
cet-15445	111	6	g.	g.	PROPN
cet-15445	111	7	&	&	CCONJ
cet-15445	111	8	de	de	PROPN
cet-15445	111	9	pinho	pinho	PROPN
cet-15445	111	10	s.	s.	PROPN
cet-15445	111	11	c.	c.	PROPN
cet-15445	111	12	,	,	PUNCT
cet-15445	111	13	2015	2015	NUM
cet-15445	111	14	,	,	PUNCT
cet-15445	111	15	lipid	lipid	NOUN
cet-15445	111	16	matrices	matrix	NOUN
cet-15445	111	17	for	for	ADP
cet-15445	111	18	nanoencapsulation	nanoencapsulation	NOUN
cet-15445	111	19	in	in	ADP
cet-15445	111	20	food	food	NOUN
cet-15445	111	21	:	:	PUNCT
cet-15445	111	22	liposomes	liposome	NOUN
cet-15445	111	23	and	and	CCONJ
cet-15445	111	24	lipid	lipid	NOUN
cet-15445	111	25	nanoparticles	nanoparticle	NOUN
cet-15445	111	26	,	,	PUNCT
cet-15445	111	27	food	food	NOUN
cet-15445	111	28	nanoscience	nanoscience	NOUN
cet-15445	111	29	and	and	CCONJ
cet-15445	111	30	nanotechnology	nanotechnology	NOUN
cet-15445	111	31	,	,	PUNCT
cet-15445	111	32	99	99	NUM
cet-15445	111	33	-	-	SYM
cet-15445	111	34	143	143	NUM
cet-15445	111	35	.	.	PUNCT
cet-15445	112	1	dubey	dubey	PROPN
cet-15445	112	2	v.	v.	PROPN
cet-15445	112	3	,	,	PUNCT
cet-15445	112	4	mishra	mishra	PROPN
cet-15445	112	5	d.	d.	PROPN
cet-15445	112	6	,	,	PUNCT
cet-15445	112	7	jain	jain	PROPN
cet-15445	112	8	n.	n.	PROPN
cet-15445	112	9	k.	k.	PROPN
cet-15445	112	10	,	,	PUNCT
cet-15445	112	11	2007	2007	NUM
cet-15445	112	12	,	,	PUNCT
cet-15445	112	13	melatonin	melatonin	NOUN
cet-15445	112	14	loaded	load	VERB
cet-15445	112	15	ethanolic	ethanolic	ADJ
cet-15445	112	16	liposomes	liposome	NOUN
cet-15445	112	17	:	:	PUNCT
cet-15445	112	18	physicochemical	physicochemical	ADJ
cet-15445	112	19	characterization	characterization	NOUN
cet-15445	112	20	and	and	CCONJ
cet-15445	112	21	enhanced	enhance	VERB
cet-15445	112	22	transdermal	transdermal	ADJ
cet-15445	112	23	delivery	delivery	NOUN
cet-15445	112	24	,	,	PUNCT
cet-15445	112	25	european	european	ADJ
cet-15445	112	26	journal	journal	PROPN
cet-15445	112	27	of	of	ADP
cet-15445	112	28	pharmaceutics	pharmaceutic	NOUN
cet-15445	112	29	and	and	CCONJ
cet-15445	112	30	biopharmaceutics	biopharmaceutic	NOUN
cet-15445	112	31	,	,	PUNCT
cet-15445	112	32	67	67	NUM
cet-15445	112	33	,	,	PUNCT
cet-15445	112	34	398405	398405	NUM
cet-15445	112	35	.	.	PUNCT
cet-15445	113	1	finotti	finotti	PROPN
cet-15445	113	2	cordeiro	cordeiro	PROPN
cet-15445	113	3	c.	c.	PROPN
cet-15445	113	4	,	,	PUNCT
cet-15445	113	5	lopardi	lopardi	PROPN
cet-15445	113	6	franco	franco	PROPN
cet-15445	113	7	l.	l.	PROPN
cet-15445	113	8	,	,	PUNCT
cet-15445	113	9	teixeira	teixeira	PROPN
cet-15445	113	10	carvalho	carvalho	PROPN
cet-15445	113	11	d.	d.	PROPN
cet-15445	113	12	,	,	PUNCT
cet-15445	113	13	bonfilio	bonfilio	PROPN
cet-15445	113	14	r.	r.	PROPN
cet-15445	113	15	,	,	PUNCT
cet-15445	113	16	2024	2024	NUM
cet-15445	113	17	,	,	PUNCT
cet-15445	113	18	impurities	impurity	NOUN
cet-15445	113	19	in	in	ADP
cet-15445	113	20	active	active	ADJ
cet-15445	113	21	pharmaceutical	pharmaceutical	ADJ
cet-15445	113	22	ingredients	ingredient	NOUN
cet-15445	113	23	and	and	CCONJ
cet-15445	113	24	drug	drug	NOUN
cet-15445	113	25	products	product	NOUN
cet-15445	113	26	:	:	PUNCT
cet-15445	113	27	a	a	DET
cet-15445	113	28	critical	critical	ADJ
cet-15445	113	29	review	review	NOUN
cet-15445	113	30	,	,	PUNCT
cet-15445	113	31	critical	critical	ADJ
cet-15445	113	32	reviews	review	NOUN
cet-15445	113	33	in	in	ADP
cet-15445	113	34	analytical	analytical	ADJ
cet-15445	113	35	chemistry	chemistry	NOUN
cet-15445	113	36	,	,	PUNCT
cet-15445	113	37	1	1	NUM
cet-15445	113	38	-	-	SYM
cet-15445	113	39	21	21	NUM
cet-15445	113	40	.	.	PUNCT
cet-15445	114	1	gouda	gouda	NOUN
cet-15445	114	2	a.	a.	PROPN
cet-15445	114	3	,	,	PUNCT
cet-15445	114	4	sakr	sakr	PROPN
cet-15445	114	5	o.	o.	PROPN
cet-15445	114	6	s.	s.	PROPN
cet-15445	114	7	,	,	PUNCT
cet-15445	114	8	nasr	nasr	PROPN
cet-15445	114	9	m.	m.	PROPN
cet-15445	114	10	,	,	PUNCT
cet-15445	114	11	sammour	sammour	PROPN
cet-15445	114	12	o.	o.	NOUN
cet-15445	114	13	,	,	PUNCT
cet-15445	114	14	2021	2021	NUM
cet-15445	114	15	,	,	PUNCT
cet-15445	114	16	ethanol	ethanol	NOUN
cet-15445	114	17	injection	injection	NOUN
cet-15445	114	18	technique	technique	NOUN
cet-15445	114	19	for	for	ADP
cet-15445	114	20	liposomes	liposome	NOUN
cet-15445	114	21	formulation	formulation	NOUN
cet-15445	114	22	:	:	PUNCT
cet-15445	114	23	an	an	DET
cet-15445	114	24	insight	insight	NOUN
cet-15445	114	25	into	into	ADP
cet-15445	114	26	development	development	NOUN
cet-15445	114	27	,	,	PUNCT
cet-15445	114	28	influencing	influence	VERB
cet-15445	114	29	factors	factor	NOUN
cet-15445	114	30	,	,	PUNCT
cet-15445	114	31	challenges	challenge	NOUN
cet-15445	114	32	and	and	CCONJ
cet-15445	114	33	applications	application	NOUN
cet-15445	114	34	,	,	PUNCT
cet-15445	114	35	journal	journal	NOUN
cet-15445	114	36	of	of	ADP
cet-15445	114	37	drug	drug	NOUN
cet-15445	114	38	delivery	delivery	NOUN
cet-15445	114	39	science	science	NOUN
cet-15445	114	40	and	and	CCONJ
cet-15445	114	41	technology	technology	NOUN
cet-15445	114	42	,	,	PUNCT
cet-15445	114	43	61	61	NUM
cet-15445	114	44	,	,	PUNCT
cet-15445	114	45	102174	102174	NUM
cet-15445	114	46	.	.	PUNCT
cet-15445	115	1	lombardo	lombardo	PROPN
cet-15445	115	2	d.	d.	PROPN
cet-15445	115	3	,	,	PUNCT
cet-15445	115	4	kiselev	kiselev	PROPN
cet-15445	115	5	m.	m.	PROPN
cet-15445	115	6	a.	a.	PROPN
cet-15445	115	7	,	,	PUNCT
cet-15445	115	8	2022	2022	NUM
cet-15445	115	9	,	,	PUNCT
cet-15445	115	10	methods	method	NOUN
cet-15445	115	11	of	of	ADP
cet-15445	115	12	liposomes	liposome	NOUN
cet-15445	115	13	preparation	preparation	NOUN
cet-15445	115	14	:	:	PUNCT
cet-15445	115	15	formation	formation	NOUN
cet-15445	115	16	and	and	CCONJ
cet-15445	115	17	control	control	NOUN
cet-15445	115	18	factors	factor	NOUN
cet-15445	115	19	of	of	ADP
cet-15445	115	20	versatile	versatile	ADJ
cet-15445	115	21	nanocarriers	nanocarrier	NOUN
cet-15445	115	22	for	for	ADP
cet-15445	115	23	biomedical	biomedical	ADJ
cet-15445	115	24	and	and	CCONJ
cet-15445	115	25	nanomedicine	nanomedicine	ADJ
cet-15445	115	26	application	application	NOUN
cet-15445	115	27	,	,	PUNCT
cet-15445	115	28	pharmaceutics	pharmaceutic	NOUN
cet-15445	115	29	,	,	PUNCT
cet-15445	115	30	14	14	NUM
cet-15445	115	31	,	,	PUNCT
cet-15445	115	32	543	543	NUM
cet-15445	115	33	.	.	PUNCT
cet-15445	116	1	kailasapathy	kailasapathy	PROPN
cet-15445	116	2	k.	k.	PROPN
cet-15445	116	3	,	,	PUNCT
cet-15445	116	4	2009	2009	NUM
cet-15445	116	5	,	,	PUNCT
cet-15445	116	6	encapsulation	encapsulation	NOUN
cet-15445	116	7	technologies	technology	NOUN
cet-15445	116	8	for	for	ADP
cet-15445	116	9	functional	functional	ADJ
cet-15445	116	10	foods	food	NOUN
cet-15445	116	11	and	and	CCONJ
cet-15445	116	12	nutraceutical	nutraceutical	ADJ
cet-15445	116	13	product	product	NOUN
cet-15445	116	14	development	development	NOUN
cet-15445	116	15	.	.	PUNCT
cet-15445	117	1	cabi	cabi	PROPN
cet-15445	117	2	reviews	reviews	PROPN
cet-15445	117	3	,	,	PUNCT
cet-15445	117	4	1	1	NUM
cet-15445	117	5	-	-	SYM
cet-15445	117	6	19	19	NUM
cet-15445	117	7	.	.	PUNCT
cet-15445	118	1	kosaraju	kosaraju	PROPN
cet-15445	118	2	s.	s.	PROPN
cet-15445	118	3	l.	l.	PROPN
cet-15445	118	4	,	,	PUNCT
cet-15445	118	5	tran	tran	PROPN
cet-15445	118	6	c.	c.	PROPN
cet-15445	118	7	,	,	PUNCT
cet-15445	118	8	lawrence	lawrence	PROPN
cet-15445	118	9	a.	a.	PROPN
cet-15445	118	10	,	,	PUNCT
cet-15445	118	11	2006	2006	NUM
cet-15445	118	12	,	,	PUNCT
cet-15445	118	13	liposomal	liposomal	ADJ
cet-15445	118	14	delivery	delivery	NOUN
cet-15445	118	15	systems	system	NOUN
cet-15445	118	16	for	for	ADP
cet-15445	118	17	encapsulation	encapsulation	NOUN
cet-15445	118	18	of	of	ADP
cet-15445	118	19	ferrous	ferrous	ADJ
cet-15445	118	20	sulfate	sulfate	NOUN
cet-15445	118	21	:	:	PUNCT
cet-15445	118	22	preparation	preparation	NOUN
cet-15445	118	23	and	and	CCONJ
cet-15445	118	24	characterization	characterization	NOUN
cet-15445	118	25	,	,	PUNCT
cet-15445	118	26	journal	journal	NOUN
cet-15445	118	27	of	of	ADP
cet-15445	118	28	liposome	liposome	NOUN
cet-15445	118	29	research	research	NOUN
cet-15445	118	30	,	,	PUNCT
cet-15445	118	31	16	16	NUM
cet-15445	118	32	,	,	PUNCT
cet-15445	118	33	347	347	NUM
cet-15445	118	34	-	-	SYM
cet-15445	118	35	358	358	NUM
cet-15445	118	36	.	.	PUNCT
cet-15445	119	1	kucuk	kucuk	NOUN
cet-15445	119	2	n.	n.	PROPN
cet-15445	119	3	,	,	PUNCT
cet-15445	119	4	primozic	primozic	PROPN
cet-15445	119	5	m.	m.	NOUN
cet-15445	119	6	,	,	PUNCT
cet-15445	119	7	knez	knez	PROPN
cet-15445	119	8	z.	z.	PROPN
cet-15445	119	9	,	,	PUNCT
cet-15445	119	10	leitgeb	leitgeb	NOUN
cet-15445	119	11	m.	m.	NOUN
cet-15445	119	12	,	,	PUNCT
cet-15445	119	13	2023	2023	NUM
cet-15445	119	14	,	,	PUNCT
cet-15445	119	15	incorporation	incorporation	NOUN
cet-15445	119	16	of	of	ADP
cet-15445	119	17	biologically	biologically	ADV
cet-15445	119	18	active	active	ADJ
cet-15445	119	19	ingredient	ingredient	NOUN
cet-15445	119	20	gallic	gallic	NOUN
cet-15445	119	21	acid	acid	NOUN
cet-15445	119	22	into	into	ADP
cet-15445	119	23	nano	nano	NOUN
cet-15445	119	24	-	-	PUNCT
cet-15445	119	25	scale	scale	NOUN
cet-15445	119	26	lipid	lipid	NOUN
cet-15445	119	27	vesicles	vesicle	NOUN
cet-15445	119	28	,	,	PUNCT
cet-15445	119	29	chemical	chemical	ADJ
cet-15445	119	30	engineering	engineering	NOUN
cet-15445	119	31	transactions	transaction	NOUN
cet-15445	119	32	,	,	PUNCT
cet-15445	119	33	100	100	NUM
cet-15445	119	34	,	,	PUNCT
cet-15445	119	35	517	517	NUM
cet-15445	119	36	-	-	SYM
cet-15445	119	37	522	522	NUM
cet-15445	119	38	.	.	PUNCT
cet-15445	120	1	marchianò	marchianò	PROPN
cet-15445	120	2	v.	v.	PROPN
cet-15445	120	3	,	,	PUNCT
cet-15445	120	4	matos	matos	PROPN
cet-15445	120	5	m.	m.	NOUN
cet-15445	120	6	,	,	PUNCT
cet-15445	120	7	serrano	serrano	PROPN
cet-15445	120	8	e.	e.	PROPN
cet-15445	120	9	,	,	PUNCT
cet-15445	120	10	álvarez	álvarez	PROPN
cet-15445	120	11	j.	j.	PROPN
cet-15445	120	12	r.	r.	PROPN
cet-15445	120	13	,	,	PUNCT
cet-15445	120	14	marcet	marcet	PROPN
cet-15445	120	15	i.	i.	PROPN
cet-15445	120	16	,	,	PUNCT
cet-15445	120	17	blanco	blanco	PROPN
cet-15445	120	18	-	-	PUNCT
cet-15445	120	19	lópez	lópez	PROPN
cet-15445	120	20	m.	m.	NOUN
cet-15445	120	21	c.	c.	PROPN
cet-15445	120	22	,	,	PUNCT
cet-15445	120	23	gutiérrez	gutiérrez	NOUN
cet-15445	120	24	g.	g.	PROPN
cet-15445	120	25	,	,	PUNCT
cet-15445	120	26	2022	2022	NUM
cet-15445	120	27	,	,	PUNCT
cet-15445	120	28	lyophilised	lyophilise	VERB
cet-15445	120	29	nanovesicles	nanovesicle	NOUN
cet-15445	120	30	loaded	load	VERB
cet-15445	120	31	with	with	ADP
cet-15445	120	32	vitamin	vitamin	NOUN
cet-15445	120	33	b12	b12	NOUN
cet-15445	120	34	,	,	PUNCT
cet-15445	120	35	journal	journal	NOUN
cet-15445	120	36	of	of	ADP
cet-15445	120	37	molecular	molecular	ADJ
cet-15445	120	38	liquids	liquid	NOUN
cet-15445	120	39	,	,	PUNCT
cet-15445	120	40	365	365	NUM
cet-15445	120	41	,	,	PUNCT
cet-15445	120	42	120129	120129	NUM
cet-15445	120	43	.	.	PUNCT
cet-15445	121	1	sofia	sofia	PROPN
cet-15445	121	2	d.	d.	PROPN
cet-15445	121	3	,	,	PUNCT
cet-15445	121	4	moffa	moffa	NOUN
cet-15445	121	5	m.	m.	NOUN
cet-15445	121	6	,	,	PUNCT
cet-15445	121	7	trucillo	trucillo	NOUN
cet-15445	121	8	,	,	PUNCT
cet-15445	121	9	p.	p.	NOUN
cet-15445	121	10	,	,	PUNCT
cet-15445	121	11	2025	2025	NUM
cet-15445	121	12	,	,	PUNCT
cet-15445	121	13	supercritical	supercritical	ADJ
cet-15445	121	14	particle	particle	NOUN
cet-15445	121	15	formation	formation	NOUN
cet-15445	121	16	(	(	PUNCT
cet-15445	121	17	spaf	spaf	NOUN
cet-15445	121	18	)	)	PUNCT
cet-15445	121	19	process	process	NOUN
cet-15445	121	20	for	for	ADP
cet-15445	121	21	the	the	DET
cet-15445	121	22	versatile	versatile	ADJ
cet-15445	121	23	production	production	NOUN
cet-15445	121	24	of	of	ADP
cet-15445	121	25	ready	ready	ADJ
cet-15445	121	26	-	-	PUNCT
cet-15445	121	27	to	to	ADP
cet-15445	121	28	-	-	PUNCT
cet-15445	121	29	market	market	NOUN
cet-15445	121	30	drug	drug	NOUN
cet-15445	121	31	delivery	delivery	NOUN
cet-15445	121	32	systems	system	NOUN
cet-15445	121	33	,	,	PUNCT
cet-15445	121	34	chemical	chemical	NOUN
cet-15445	121	35	engineering	engineering	NOUN
cet-15445	121	36	science	science	NOUN
cet-15445	121	37	,	,	PUNCT
cet-15445	121	38	302	302	NUM
cet-15445	121	39	,	,	PUNCT
cet-15445	121	40	120918	120918	NUM
cet-15445	121	41	.	.	PUNCT
cet-15445	122	1	trucillo	trucillo	NOUN
cet-15445	122	2	,	,	PUNCT
cet-15445	122	3	p.	p.	PROPN
cet-15445	122	4	,	,	PUNCT
cet-15445	122	5	campardelli	campardelli	PROPN
cet-15445	122	6	,	,	PUNCT
cet-15445	122	7	r.	r.	PROPN
cet-15445	122	8	,	,	PUNCT
cet-15445	122	9	reverchon	reverchon	PROPN
cet-15445	122	10	,	,	PUNCT
cet-15445	122	11	e.	e.	PROPN
cet-15445	122	12	,	,	PUNCT
cet-15445	122	13	2020	2020	NUM
cet-15445	122	14	,	,	PUNCT
cet-15445	122	15	liposomes	liposome	NOUN
cet-15445	122	16	:	:	PUNCT
cet-15445	122	17	from	from	ADP
cet-15445	122	18	bangham	bangham	PROPN
cet-15445	122	19	to	to	ADP
cet-15445	122	20	supercritical	supercritical	ADJ
cet-15445	122	21	fluids	fluid	NOUN
cet-15445	122	22	,	,	PUNCT
cet-15445	122	23	processes	process	NOUN
cet-15445	122	24	,	,	PUNCT
cet-15445	122	25	8	8	NUM
cet-15445	122	26	,	,	PUNCT
cet-15445	122	27	1022	1022	NUM
cet-15445	122	28	.	.	PUNCT
cet-15445	123	1	were	be	AUX
cet-15445	123	2	,	,	PUNCT
cet-15445	123	3	l.	l.	PROPN
cet-15445	123	4	m.	m.	PROPN
cet-15445	123	5	,	,	PUNCT
cet-15445	123	6	bruce	bruce	PROPN
cet-15445	123	7	,	,	PUNCT
cet-15445	123	8	b.	b.	PROPN
cet-15445	123	9	d.	d.	PROPN
cet-15445	123	10	,	,	PUNCT
cet-15445	123	11	davidson	davidson	PROPN
cet-15445	123	12	,	,	PUNCT
cet-15445	123	13	p.	p.	NOUN
cet-15445	123	14	m.	m.	NOUN
cet-15445	123	15	,	,	PUNCT
cet-15445	123	16	&	&	CCONJ
cet-15445	123	17	weiss	weiss	PROPN
cet-15445	123	18	,	,	PUNCT
cet-15445	123	19	j.	j.	PROPN
cet-15445	123	20	(	(	PUNCT
cet-15445	123	21	2003	2003	NUM
cet-15445	123	22	)	)	PUNCT
cet-15445	123	23	.	.	PUNCT
cet-15445	124	1	size	size	NOUN
cet-15445	124	2	,	,	PUNCT
cet-15445	124	3	stability	stability	NOUN
cet-15445	124	4	,	,	PUNCT
cet-15445	124	5	and	and	CCONJ
cet-15445	124	6	entrapment	entrapment	ADJ
cet-15445	124	7	efficiency	efficiency	NOUN
cet-15445	124	8	of	of	ADP
cet-15445	124	9	phospholipid	phospholipid	NOUN
cet-15445	124	10	nanocapsules	nanocapsule	NOUN
cet-15445	124	11	containing	contain	VERB
cet-15445	124	12	polypeptide	polypeptide	ADJ
cet-15445	124	13	antimicrobials	antimicrobial	NOUN
cet-15445	124	14	.	.	PUNCT
cet-15445	125	1	journal	journal	NOUN
cet-15445	125	2	of	of	ADP
cet-15445	125	3	agricultural	agricultural	ADJ
cet-15445	125	4	and	and	CCONJ
cet-15445	125	5	food	food	NOUN
cet-15445	125	6	chemistry	chemistry	NOUN
cet-15445	125	7	,	,	PUNCT
cet-15445	125	8	51(27	51(27	NUM
cet-15445	125	9	)	)	PUNCT
cet-15445	125	10	,	,	PUNCT
cet-15445	125	11	8073	8073	NUM
cet-15445	125	12	-	-	SYM
cet-15445	125	13	8079	8079	NUM
cet-15445	125	14	.	.	PUNCT
cet-15445	126	1	1170	1170	NUM
cet-15445	126	2	cet-vol117-b.pdf	cet-vol117-b.pdf	X
cet-15445	126	3	277sofia.pdf	277sofia.pdf	NUM
cet-15445	126	4	innovative	innovative	ADJ
cet-15445	126	5	supercritical	supercritical	ADJ
cet-15445	126	6	particle	particle	NOUN
cet-15445	126	7	formation	formation	NOUN
cet-15445	126	8	for	for	ADP
cet-15445	126	9	the	the	DET
cet-15445	126	10	sustainable	sustainable	ADJ
cet-15445	126	11	manufacturing	manufacturing	NOUN
cet-15445	126	12	of	of	ADP
cet-15445	126	13	advanced	advanced	ADJ
cet-15445	126	14	drug	drug	NOUN
cet-15445	126	15	delivery	delivery	NOUN
cet-15445	126	16	systems	system	NOUN