id	sid	tid	token	lemma	pos
cet-15446	1	1	doi	doi	NOUN
cet-15446	1	2	:	:	PUNCT
cet-15446	1	3	10.3303	10.3303	NUM
cet-15446	1	4	/	/	SYM
cet-15446	1	5	cet25117196	cet25117196	ADJ
cet-15446	1	6	paper	paper	NOUN
cet-15446	1	7	received	receive	VERB
cet-15446	1	8	:	:	PUNCT
cet-15446	1	9	4	4	NUM
cet-15446	1	10	january	january	NOUN
cet-15446	1	11	2025	2025	NUM
cet-15446	1	12	;	;	PUNCT
cet-15446	1	13	revised	revise	VERB
cet-15446	1	14	:	:	PUNCT
cet-15446	1	15	24	24	NUM
cet-15446	1	16	february	february	NOUN
cet-15446	1	17	2025	2025	NUM
cet-15446	1	18	;	;	PUNCT
cet-15446	1	19	accepted	accept	VERB
cet-15446	1	20	:	:	PUNCT
cet-15446	1	21	12	12	NUM
cet-15446	1	22	may	may	AUX
cet-15446	1	23	2025	2025	NUM
cet-15446	1	24	please	please	INTJ
cet-15446	1	25	cite	cite	VERB
cet-15446	1	26	this	this	DET
cet-15446	1	27	article	article	NOUN
cet-15446	1	28	as	as	ADP
cet-15446	1	29	:	:	PUNCT
cet-15446	1	30	sarnelli	sarnelli	PROPN
cet-15446	1	31	s.	s.	PROPN
cet-15446	1	32	,	,	PUNCT
cet-15446	1	33	reverchon	reverchon	PROPN
cet-15446	1	34	e.	e.	PROPN
cet-15446	1	35	,	,	PUNCT
cet-15446	1	36	baldino	baldino	PROPN
cet-15446	1	37	l.	l.	PROPN
cet-15446	1	38	,	,	PUNCT
cet-15446	1	39	2025	2025	NUM
cet-15446	1	40	,	,	PUNCT
cet-15446	1	41	deformable	deformable	ADJ
cet-15446	1	42	nanovesicles	nanovesicle	NOUN
cet-15446	1	43	produced	produce	VERB
cet-15446	1	44	by	by	ADP
cet-15446	1	45	using	use	VERB
cet-15446	1	46	a	a	DET
cet-15446	1	47	supercritical	supercritical	ADJ
cet-15446	1	48	technology	technology	NOUN
cet-15446	1	49	for	for	ADP
cet-15446	1	50	enhanced	enhanced	ADJ
cet-15446	1	51	transdermal	transdermal	ADJ
cet-15446	1	52	drug	drug	NOUN
cet-15446	1	53	delivery	delivery	NOUN
cet-15446	1	54	,	,	PUNCT
cet-15446	1	55	chemical	chemical	NOUN
cet-15446	1	56	engineering	engineering	NOUN
cet-15446	1	57	transactions	transaction	NOUN
cet-15446	1	58	,	,	PUNCT
cet-15446	1	59	117	117	NUM
cet-15446	1	60	,	,	PUNCT
cet-15446	1	61	1171	1171	NUM
cet-15446	1	62	-	-	SYM
cet-15446	1	63	1176	1176	NUM
cet-15446	1	64	doi:10.3303	doi:10.3303	NOUN
cet-15446	1	65	/	/	SYM
cet-15446	1	66	cet25117196	cet25117196	ADJ
cet-15446	1	67	chemical	chemical	PROPN
cet-15446	1	68	engineering	engineering	NOUN
cet-15446	1	69	transactions	transaction	NOUN
cet-15446	1	70	vol	vol	NOUN
cet-15446	1	71	.	.	PROPN
cet-15446	1	72	117	117	NUM
cet-15446	1	73	,	,	PUNCT
cet-15446	1	74	2025	2025	NUM
cet-15446	1	75	a	a	DET
cet-15446	1	76	publication	publication	NOUN
cet-15446	1	77	of	of	ADP
cet-15446	1	78	the	the	DET
cet-15446	1	79	italian	italian	ADJ
cet-15446	1	80	association	association	NOUN
cet-15446	1	81	of	of	ADP
cet-15446	1	82	chemical	chemical	PROPN
cet-15446	1	83	engineering	engineering	NOUN
cet-15446	1	84	online	online	ADV
cet-15446	1	85	at	at	ADP
cet-15446	1	86	www.cetjournal.it	www.cetjournal.it	PROPN
cet-15446	1	87	guest	guest	NOUN
cet-15446	1	88	editors	editor	NOUN
cet-15446	1	89	:	:	PUNCT
cet-15446	1	90	fabrizio	fabrizio	PROPN
cet-15446	1	91	bezzo	bezzo	PROPN
cet-15446	1	92	,	,	PUNCT
cet-15446	1	93	flavio	flavio	PROPN
cet-15446	1	94	manenti	manenti	PROPN
cet-15446	1	95	,	,	PUNCT
cet-15446	1	96	gabriele	gabriele	PROPN
cet-15446	1	97	pannocchia	pannocchia	PROPN
cet-15446	1	98	,	,	PUNCT
cet-15446	1	99	almerinda	almerinda	PROPN
cet-15446	1	100	di	di	PROPN
cet-15446	1	101	benedetto	benedetto	PROPN
cet-15446	1	102	copyright	copyright	PROPN
cet-15446	1	103	©	©	PROPN
cet-15446	1	104	2025	2025	NUM
cet-15446	1	105	,	,	PUNCT
cet-15446	1	106	aidic	aidic	ADJ
cet-15446	1	107	servizi	servizi	PROPN
cet-15446	1	108	s.r.l	s.r.l	NOUN
cet-15446	1	109	.	.	PUNCT
cet-15446	2	1	isbn	isbn	PROPN
cet-15446	2	2	979	979	NUM
cet-15446	2	3	-	-	SYM
cet-15446	2	4	12	12	NUM
cet-15446	2	5	-	-	PUNCT
cet-15446	2	6	81206	81206	NUM
cet-15446	2	7	-	-	SYM
cet-15446	2	8	17	17	NUM
cet-15446	2	9	-	-	SYM
cet-15446	2	10	5	5	NUM
cet-15446	2	11	;	;	PUNCT
cet-15446	2	12	issn	issn	PROPN
cet-15446	2	13	2283	2283	NUM
cet-15446	2	14	-	-	SYM
cet-15446	2	15	9216	9216	NUM
cet-15446	2	16	deformable	deformable	ADJ
cet-15446	2	17	nanovesicles	nanovesicle	NOUN
cet-15446	2	18	produced	produce	VERB
cet-15446	2	19	by	by	ADP
cet-15446	2	20	using	use	VERB
cet-15446	2	21	a	a	DET
cet-15446	2	22	supercritical	supercritical	ADJ
cet-15446	2	23	technology	technology	NOUN
cet-15446	2	24	for	for	ADP
cet-15446	2	25	enhanced	enhanced	ADJ
cet-15446	2	26	transdermal	transdermal	ADJ
cet-15446	2	27	drug	drug	NOUN
cet-15446	2	28	delivery	delivery	NOUN
cet-15446	2	29	sonia	sonia	PROPN
cet-15446	2	30	sarnelli	sarnelli	PROPN
cet-15446	2	31	,	,	PUNCT
cet-15446	2	32	ernesto	ernesto	PROPN
cet-15446	2	33	reverchon	reverchon	PROPN
cet-15446	2	34	,	,	PUNCT
cet-15446	2	35	lucia	lucia	PROPN
cet-15446	2	36	baldino	baldino	PROPN
cet-15446	2	37	*	*	PROPN
cet-15446	2	38	department	department	PROPN
cet-15446	2	39	of	of	ADP
cet-15446	2	40	industrial	industrial	ADJ
cet-15446	2	41	engineering	engineering	NOUN
cet-15446	2	42	,	,	PUNCT
cet-15446	2	43	university	university	NOUN
cet-15446	2	44	of	of	ADP
cet-15446	2	45	salerno	salerno	PROPN
cet-15446	2	46	,	,	PUNCT
cet-15446	2	47	via	via	ADP
cet-15446	2	48	giovanni	giovanni	PROPN
cet-15446	2	49	paolo	paolo	PROPN
cet-15446	2	50	ii	ii	PROPN
cet-15446	2	51	,	,	PUNCT
cet-15446	2	52	132	132	NUM
cet-15446	2	53	,	,	PUNCT
cet-15446	2	54	84084	84084	NUM
cet-15446	2	55	,	,	PUNCT
cet-15446	2	56	fisciano	fisciano	X
cet-15446	2	57	(	(	PUNCT
cet-15446	2	58	sa	sa	PROPN
cet-15446	2	59	)	)	PUNCT
cet-15446	2	60	,	,	PUNCT
cet-15446	2	61	italy	italy	PROPN
cet-15446	2	62	lbaldino@unisa.it	lbaldino@unisa.it	PROPN
cet-15446	2	63	transfersomes	transfersome	NOUN
cet-15446	2	64	are	be	AUX
cet-15446	2	65	promising	promise	VERB
cet-15446	2	66	nanocarriers	nanocarrier	NOUN
cet-15446	2	67	for	for	ADP
cet-15446	2	68	transdermal	transdermal	ADJ
cet-15446	2	69	drug	drug	NOUN
cet-15446	2	70	delivery	delivery	NOUN
cet-15446	2	71	since	since	SCONJ
cet-15446	2	72	they	they	PRON
cet-15446	2	73	are	be	AUX
cet-15446	2	74	ultra	ultra	ADJ
cet-15446	2	75	-	-	ADJ
cet-15446	2	76	deformable	deformable	ADJ
cet-15446	2	77	liposomes	liposome	NOUN
cet-15446	2	78	constituted	constitute	VERB
cet-15446	2	79	of	of	ADP
cet-15446	2	80	phospholipids	phospholipid	NOUN
cet-15446	2	81	and	and	CCONJ
cet-15446	2	82	surfactants	surfactant	NOUN
cet-15446	2	83	;	;	PUNCT
cet-15446	2	84	these	these	DET
cet-15446	2	85	latter	latter	ADJ
cet-15446	2	86	compounds	compound	NOUN
cet-15446	2	87	work	work	NOUN
cet-15446	2	88	as	as	ADP
cet-15446	2	89	edge	edge	NOUN
cet-15446	2	90	activators	activator	NOUN
cet-15446	2	91	,	,	PUNCT
cet-15446	2	92	allowing	allow	VERB
cet-15446	2	93	the	the	DET
cet-15446	2	94	deformation	deformation	NOUN
cet-15446	2	95	of	of	ADP
cet-15446	2	96	the	the	DET
cet-15446	2	97	vesicle	vesicle	NOUN
cet-15446	2	98	.	.	PUNCT
cet-15446	3	1	in	in	ADP
cet-15446	3	2	this	this	DET
cet-15446	3	3	work	work	NOUN
cet-15446	3	4	,	,	PUNCT
cet-15446	3	5	transfersomes	transfersome	NOUN
cet-15446	3	6	were	be	AUX
cet-15446	3	7	produced	produce	VERB
cet-15446	3	8	by	by	ADP
cet-15446	3	9	using	use	VERB
cet-15446	3	10	supersomes	supersome	NOUN
cet-15446	3	11	,	,	PUNCT
cet-15446	3	12	an	an	DET
cet-15446	3	13	innovative	innovative	ADJ
cet-15446	3	14	and	and	CCONJ
cet-15446	3	15	continuous	continuous	ADJ
cet-15446	3	16	process	process	NOUN
cet-15446	3	17	assisted	assist	VERB
cet-15446	3	18	by	by	ADP
cet-15446	3	19	supercritical	supercritical	ADJ
cet-15446	3	20	carbon	carbon	NOUN
cet-15446	3	21	dioxide	dioxide	NOUN
cet-15446	3	22	(	(	PUNCT
cet-15446	3	23	sc	sc	NOUN
cet-15446	3	24	-	-	PUNCT
cet-15446	3	25	co2	co2	NOUN
cet-15446	3	26	)	)	PUNCT
cet-15446	3	27	.	.	PUNCT
cet-15446	4	1	different	different	ADJ
cet-15446	4	2	amounts	amount	NOUN
cet-15446	4	3	of	of	ADP
cet-15446	4	4	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	4	5	(	(	PUNCT
cet-15446	4	6	pc	pc	NOUN
cet-15446	4	7	)	)	PUNCT
cet-15446	4	8	(	(	PUNCT
cet-15446	4	9	i.e.	i.e.	X
cet-15446	4	10	,	,	PUNCT
cet-15446	4	11	500	500	NUM
cet-15446	4	12	,	,	PUNCT
cet-15446	4	13	1000	1000	NUM
cet-15446	4	14	,	,	PUNCT
cet-15446	4	15	and	and	CCONJ
cet-15446	4	16	2000	2000	NUM
cet-15446	4	17	mg	mg	NUM
cet-15446	4	18	)	)	PUNCT
cet-15446	4	19	were	be	AUX
cet-15446	4	20	tested	test	VERB
cet-15446	4	21	;	;	PUNCT
cet-15446	4	22	whereas	whereas	ADV
cet-15446	4	23	,	,	PUNCT
cet-15446	4	24	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	4	25	/	/	SYM
cet-15446	4	26	span	span	VERB
cet-15446	4	27	80	80	NUM
cet-15446	4	28	weight	weight	NOUN
cet-15446	4	29	ratio	ratio	NOUN
cet-15446	4	30	was	be	AUX
cet-15446	4	31	maintained	maintain	VERB
cet-15446	4	32	constant	constant	ADJ
cet-15446	4	33	at	at	ADP
cet-15446	4	34	80:20	80:20	NUM
cet-15446	4	35	value	value	NOUN
cet-15446	4	36	.	.	PUNCT
cet-15446	5	1	supersomes	supersome	NOUN
cet-15446	5	2	operating	operating	NOUN
cet-15446	5	3	conditions	condition	NOUN
cet-15446	5	4	were	be	AUX
cet-15446	5	5	fixed	fix	VERB
cet-15446	5	6	at	at	ADP
cet-15446	5	7	100	100	NUM
cet-15446	5	8	bar	bar	NOUN
cet-15446	5	9	and	and	CCONJ
cet-15446	5	10	40	40	NUM
cet-15446	5	11	°	°	NOUN
cet-15446	5	12	c	c	NOUN
cet-15446	5	13	.	.	PUNCT
cet-15446	6	1	transfersomes	transfersome	NOUN
cet-15446	6	2	with	with	ADP
cet-15446	6	3	nanometric	nanometric	ADJ
cet-15446	6	4	size	size	NOUN
cet-15446	6	5	and	and	CCONJ
cet-15446	6	6	unimodal	unimodal	ADJ
cet-15446	6	7	size	size	NOUN
cet-15446	6	8	distribution	distribution	NOUN
cet-15446	6	9	were	be	AUX
cet-15446	6	10	obtained	obtain	VERB
cet-15446	6	11	without	without	ADP
cet-15446	6	12	postprocessing	postprocesse	VERB
cet-15446	6	13	operations	operation	NOUN
cet-15446	6	14	(	(	PUNCT
cet-15446	6	15	i.e.	i.e.	X
cet-15446	6	16	,	,	PUNCT
cet-15446	6	17	solvent	solvent	ADJ
cet-15446	6	18	removal	removal	NOUN
cet-15446	6	19	or	or	CCONJ
cet-15446	6	20	filtration	filtration	NOUN
cet-15446	6	21	)	)	PUNCT
cet-15446	6	22	,	,	PUNCT
cet-15446	6	23	which	which	PRON
cet-15446	6	24	are	be	AUX
cet-15446	6	25	mandatory	mandatory	ADJ
cet-15446	6	26	steps	step	NOUN
cet-15446	6	27	for	for	ADP
cet-15446	6	28	conventional	conventional	ADJ
cet-15446	6	29	production	production	NOUN
cet-15446	6	30	methods	method	NOUN
cet-15446	6	31	.	.	PUNCT
cet-15446	7	1	the	the	DET
cet-15446	7	2	optimized	optimize	VERB
cet-15446	7	3	formulation	formulation	NOUN
cet-15446	7	4	resulted	result	VERB
cet-15446	7	5	in	in	ADP
cet-15446	7	6	transfersomes	transfersome	NOUN
cet-15446	7	7	of	of	ADP
cet-15446	7	8	about	about	ADV
cet-15446	7	9	180	180	NUM
cet-15446	7	10	nm	nm	ADJ
cet-15446	7	11	mean	mean	NOUN
cet-15446	7	12	diameter	diameter	NOUN
cet-15446	7	13	,	,	PUNCT
cet-15446	7	14	with	with	ADP
cet-15446	7	15	a	a	DET
cet-15446	7	16	low	low	ADJ
cet-15446	7	17	polydispersity	polydispersity	NOUN
cet-15446	7	18	index	index	NOUN
cet-15446	7	19	(	(	PUNCT
cet-15446	7	20	equal	equal	ADJ
cet-15446	7	21	to	to	ADP
cet-15446	7	22	0.304	0.304	NUM
cet-15446	7	23	)	)	PUNCT
cet-15446	7	24	and	and	CCONJ
cet-15446	7	25	a	a	DET
cet-15446	7	26	-21.00	-21.00	PROPN
cet-15446	7	27	mv	mv	PROPN
cet-15446	7	28	zeta	zeta	NOUN
cet-15446	7	29	-	-	PUNCT
cet-15446	7	30	potential	potential	NOUN
cet-15446	7	31	.	.	PUNCT
cet-15446	8	1	diclofenac	diclofenac	ADJ
cet-15446	8	2	sodium	sodium	NOUN
cet-15446	8	3	(	(	PUNCT
cet-15446	8	4	df	df	PROPN
cet-15446	8	5	)	)	PUNCT
cet-15446	8	6	was	be	AUX
cet-15446	8	7	then	then	ADV
cet-15446	8	8	loaded	load	VERB
cet-15446	8	9	into	into	ADP
cet-15446	8	10	these	these	DET
cet-15446	8	11	transfersomes	transfersome	NOUN
cet-15446	8	12	with	with	ADP
cet-15446	8	13	an	an	DET
cet-15446	8	14	encapsulation	encapsulation	NOUN
cet-15446	8	15	efficiency	efficiency	NOUN
cet-15446	8	16	of	of	ADP
cet-15446	8	17	74	74	NUM
cet-15446	8	18	%	%	NOUN
cet-15446	8	19	;	;	PUNCT
cet-15446	8	20	drug	drug	NOUN
cet-15446	8	21	release	release	NOUN
cet-15446	8	22	tests	test	NOUN
cet-15446	8	23	showed	show	VERB
cet-15446	8	24	a	a	DET
cet-15446	8	25	prolonged	prolonged	ADJ
cet-15446	8	26	release	release	NOUN
cet-15446	8	27	of	of	ADP
cet-15446	8	28	df	df	NOUN
cet-15446	8	29	up	up	ADP
cet-15446	8	30	to	to	ADP
cet-15446	8	31	about	about	ADP
cet-15446	8	32	four	four	NUM
cet-15446	8	33	times	time	NOUN
cet-15446	8	34	than	than	ADP
cet-15446	8	35	drug	drug	NOUN
cet-15446	8	36	alone	alone	ADV
cet-15446	8	37	.	.	PUNCT
cet-15446	9	1	1	1	X
cet-15446	9	2	.	.	X
cet-15446	9	3	introduction	introduction	NOUN
cet-15446	9	4	transdermal	transdermal	ADJ
cet-15446	9	5	drug	drug	NOUN
cet-15446	9	6	delivery	delivery	NOUN
cet-15446	9	7	(	(	PUNCT
cet-15446	9	8	tdd	tdd	NOUN
cet-15446	9	9	)	)	PUNCT
cet-15446	9	10	is	be	AUX
cet-15446	9	11	proposed	propose	VERB
cet-15446	9	12	as	as	ADP
cet-15446	9	13	a	a	DET
cet-15446	9	14	promising	promising	ADJ
cet-15446	9	15	alternative	alternative	NOUN
cet-15446	9	16	to	to	ADP
cet-15446	9	17	conventional	conventional	ADJ
cet-15446	9	18	oral	oral	ADJ
cet-15446	9	19	drug	drug	NOUN
cet-15446	9	20	administration	administration	NOUN
cet-15446	9	21	,	,	PUNCT
cet-15446	9	22	to	to	PART
cet-15446	9	23	avoid	avoid	VERB
cet-15446	9	24	problems	problem	NOUN
cet-15446	9	25	related	relate	VERB
cet-15446	9	26	to	to	ADP
cet-15446	9	27	the	the	DET
cet-15446	9	28	first	first	ADJ
cet-15446	9	29	-	-	PUNCT
cet-15446	9	30	pass	pass	VERB
cet-15446	9	31	metabolism	metabolism	NOUN
cet-15446	9	32	and	and	CCONJ
cet-15446	9	33	the	the	DET
cet-15446	9	34	clearance	clearance	NOUN
cet-15446	9	35	of	of	ADP
cet-15446	9	36	drugs	drug	NOUN
cet-15446	9	37	by	by	ADP
cet-15446	9	38	the	the	DET
cet-15446	9	39	liver	liver	NOUN
cet-15446	9	40	(	(	PUNCT
cet-15446	9	41	matharoo	matharoo	PROPN
cet-15446	9	42	et	et	PROPN
cet-15446	9	43	al	al	PROPN
cet-15446	9	44	.	.	PROPN
cet-15446	9	45	,	,	PUNCT
cet-15446	9	46	2024	2024	NUM
cet-15446	9	47	)	)	PUNCT
cet-15446	9	48	.	.	PUNCT
cet-15446	10	1	tdd	tdd	NOUN
cet-15446	10	2	systems	system	NOUN
cet-15446	10	3	could	could	AUX
cet-15446	10	4	enable	enable	VERB
cet-15446	10	5	direct	direct	ADJ
cet-15446	10	6	adsorption	adsorption	NOUN
cet-15446	10	7	of	of	ADP
cet-15446	10	8	drugs	drug	NOUN
cet-15446	10	9	through	through	ADP
cet-15446	10	10	the	the	DET
cet-15446	10	11	skin	skin	NOUN
cet-15446	10	12	into	into	ADP
cet-15446	10	13	the	the	DET
cet-15446	10	14	bloodstream	bloodstream	NOUN
cet-15446	10	15	,	,	PUNCT
cet-15446	10	16	allowing	allow	VERB
cet-15446	10	17	controlled	control	VERB
cet-15446	10	18	drug	drug	NOUN
cet-15446	10	19	release	release	NOUN
cet-15446	10	20	and	and	CCONJ
cet-15446	10	21	minimizing	minimize	VERB
cet-15446	10	22	side	side	NOUN
cet-15446	10	23	effects	effect	NOUN
cet-15446	10	24	(	(	PUNCT
cet-15446	10	25	ghaferi	ghaferi	NOUN
cet-15446	10	26	et	et	PROPN
cet-15446	10	27	al	al	PROPN
cet-15446	10	28	.	.	PROPN
cet-15446	10	29	,	,	PUNCT
cet-15446	10	30	2024	2024	NUM
cet-15446	10	31	)	)	PUNCT
cet-15446	10	32	.	.	PUNCT
cet-15446	11	1	liposomes	liposome	NOUN
cet-15446	11	2	and	and	CCONJ
cet-15446	11	3	niosomes	niosome	NOUN
cet-15446	11	4	can	can	AUX
cet-15446	11	5	be	be	AUX
cet-15446	11	6	used	use	VERB
cet-15446	11	7	as	as	ADP
cet-15446	11	8	delivery	delivery	NOUN
cet-15446	11	9	systems	system	NOUN
cet-15446	11	10	for	for	ADP
cet-15446	11	11	both	both	CCONJ
cet-15446	11	12	hydrophilic	hydrophilic	ADJ
cet-15446	11	13	and	and	CCONJ
cet-15446	11	14	lipophilic	lipophilic	ADJ
cet-15446	11	15	drugs	drug	NOUN
cet-15446	11	16	,	,	PUNCT
cet-15446	11	17	since	since	SCONJ
cet-15446	11	18	they	they	PRON
cet-15446	11	19	are	be	AUX
cet-15446	11	20	composed	compose	VERB
cet-15446	11	21	of	of	ADP
cet-15446	11	22	a	a	DET
cet-15446	11	23	lipid	lipid	NOUN
cet-15446	11	24	bilayer	bilayer	NOUN
cet-15446	11	25	that	that	PRON
cet-15446	11	26	mimics	mimic	VERB
cet-15446	11	27	the	the	DET
cet-15446	11	28	cellular	cellular	ADJ
cet-15446	11	29	membrane	membrane	NOUN
cet-15446	11	30	structure	structure	NOUN
cet-15446	11	31	(	(	PUNCT
cet-15446	11	32	de	de	X
cet-15446	11	33	a.c	a.c	PROPN
cet-15446	11	34	.	.	PROPN
cet-15446	11	35	kodel	kodel	PROPN
cet-15446	11	36	et	et	PROPN
cet-15446	11	37	al	al	PROPN
cet-15446	11	38	.	.	PROPN
cet-15446	11	39	,	,	PUNCT
cet-15446	11	40	2024	2024	NUM
cet-15446	11	41	)	)	PUNCT
cet-15446	11	42	.	.	PUNCT
cet-15446	12	1	however	however	ADV
cet-15446	12	2	,	,	PUNCT
cet-15446	12	3	their	their	PRON
cet-15446	12	4	transdermal	transdermal	ADJ
cet-15446	12	5	application	application	NOUN
cet-15446	12	6	is	be	AUX
cet-15446	12	7	hindered	hinder	VERB
cet-15446	12	8	by	by	ADP
cet-15446	12	9	the	the	DET
cet-15446	12	10	difficulty	difficulty	NOUN
cet-15446	12	11	to	to	PART
cet-15446	12	12	penetrate	penetrate	VERB
cet-15446	12	13	the	the	DET
cet-15446	12	14	stratum	stratum	NOUN
cet-15446	12	15	corneum	corneum	NOUN
cet-15446	12	16	(	(	PUNCT
cet-15446	12	17	i.e.	i.e.	X
cet-15446	12	18	,	,	PUNCT
cet-15446	12	19	the	the	DET
cet-15446	12	20	outermost	outermost	ADJ
cet-15446	12	21	layer	layer	NOUN
cet-15446	12	22	of	of	ADP
cet-15446	12	23	the	the	DET
cet-15446	12	24	skin	skin	NOUN
cet-15446	12	25	)	)	PUNCT
cet-15446	12	26	due	due	ADP
cet-15446	12	27	to	to	ADP
cet-15446	12	28	their	their	PRON
cet-15446	12	29	rigid	rigid	ADJ
cet-15446	12	30	structure	structure	NOUN
cet-15446	12	31	(	(	PUNCT
cet-15446	12	32	elron	elron	NOUN
cet-15446	12	33	-	-	PUNCT
cet-15446	12	34	gross	gross	PROPN
cet-15446	12	35	et	et	PROPN
cet-15446	12	36	al	al	PROPN
cet-15446	12	37	.	.	PROPN
cet-15446	12	38	,	,	PUNCT
cet-15446	12	39	2009	2009	NUM
cet-15446	12	40	)	)	PUNCT
cet-15446	12	41	.	.	PUNCT
cet-15446	13	1	to	to	PART
cet-15446	13	2	address	address	VERB
cet-15446	13	3	this	this	DET
cet-15446	13	4	challenge	challenge	NOUN
cet-15446	13	5	,	,	PUNCT
cet-15446	13	6	deformable	deformable	ADJ
cet-15446	13	7	liposomes	liposome	NOUN
cet-15446	13	8	,	,	PUNCT
cet-15446	13	9	named	name	VERB
cet-15446	13	10	“	"	PUNCT
cet-15446	13	11	transfersomes	transfersome	NOUN
cet-15446	13	12	”	"	PUNCT
cet-15446	13	13	,	,	PUNCT
cet-15446	13	14	have	have	AUX
cet-15446	13	15	been	be	AUX
cet-15446	13	16	developed	develop	VERB
cet-15446	13	17	.	.	PUNCT
cet-15446	14	1	the	the	DET
cet-15446	14	2	introduction	introduction	NOUN
cet-15446	14	3	of	of	ADP
cet-15446	14	4	edge	edge	NOUN
cet-15446	14	5	activators	activator	NOUN
cet-15446	14	6	,	,	PUNCT
cet-15446	14	7	typically	typically	ADV
cet-15446	14	8	surfactants	surfactant	NOUN
cet-15446	14	9	like	like	ADP
cet-15446	14	10	tween	tween	NOUN
cet-15446	14	11	80	80	NUM
cet-15446	14	12	or	or	CCONJ
cet-15446	14	13	span	span	VERB
cet-15446	14	14	80	80	NUM
cet-15446	14	15	,	,	PUNCT
cet-15446	14	16	in	in	ADP
cet-15446	14	17	the	the	DET
cet-15446	14	18	lipid	lipid	NOUN
cet-15446	14	19	bilayer	bilayer	NOUN
cet-15446	14	20	composed	compose	VERB
cet-15446	14	21	of	of	ADP
cet-15446	14	22	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	14	23	,	,	PUNCT
cet-15446	14	24	leads	lead	VERB
cet-15446	14	25	to	to	ADP
cet-15446	14	26	the	the	DET
cet-15446	14	27	formation	formation	NOUN
cet-15446	14	28	of	of	ADP
cet-15446	14	29	largely	largely	ADV
cet-15446	14	30	deformable	deformable	ADJ
cet-15446	14	31	vesicles	vesicle	NOUN
cet-15446	14	32	with	with	ADP
cet-15446	14	33	respect	respect	NOUN
cet-15446	14	34	to	to	ADP
cet-15446	14	35	liposomes	liposome	NOUN
cet-15446	14	36	(	(	PUNCT
cet-15446	14	37	patel	patel	PROPN
cet-15446	14	38	et	et	PROPN
cet-15446	14	39	al	al	PROPN
cet-15446	14	40	.	.	PROPN
cet-15446	14	41	,	,	PUNCT
cet-15446	14	42	2024	2024	NUM
cet-15446	14	43	)	)	PUNCT
cet-15446	14	44	.	.	PUNCT
cet-15446	15	1	this	this	DET
cet-15446	15	2	fact	fact	NOUN
cet-15446	15	3	makes	make	VERB
cet-15446	15	4	transfersomes	transfersome	NOUN
cet-15446	15	5	promising	promise	VERB
cet-15446	15	6	candidates	candidate	NOUN
cet-15446	15	7	for	for	ADP
cet-15446	15	8	transdermal	transdermal	ADJ
cet-15446	15	9	drug	drug	NOUN
cet-15446	15	10	delivery	delivery	NOUN
cet-15446	15	11	,	,	PUNCT
cet-15446	15	12	capable	capable	ADJ
cet-15446	15	13	of	of	ADP
cet-15446	15	14	penetrating	penetrate	VERB
cet-15446	15	15	through	through	ADP
cet-15446	15	16	tight	tight	ADJ
cet-15446	15	17	intercellular	intercellular	ADJ
cet-15446	15	18	spaces	space	NOUN
cet-15446	15	19	of	of	ADP
cet-15446	15	20	the	the	DET
cet-15446	15	21	skin	skin	NOUN
cet-15446	15	22	barrier	barrier	NOUN
cet-15446	15	23	(	(	PUNCT
cet-15446	15	24	prausnitz	prausnitz	NOUN
cet-15446	15	25	and	and	CCONJ
cet-15446	15	26	langer	langer	NOUN
cet-15446	15	27	,	,	PUNCT
cet-15446	15	28	2008	2008	NUM
cet-15446	15	29	)	)	PUNCT
cet-15446	15	30	.	.	PUNCT
cet-15446	16	1	several	several	ADJ
cet-15446	16	2	non	non	ADJ
cet-15446	16	3	-	-	ADJ
cet-15446	16	4	steroidal	steroidal	ADJ
cet-15446	16	5	anti	anti	ADJ
cet-15446	16	6	-	-	ADJ
cet-15446	16	7	inflammatory	inflammatory	ADJ
cet-15446	16	8	drugs	drug	NOUN
cet-15446	16	9	(	(	PUNCT
cet-15446	16	10	nsaids	nsaid	NOUN
cet-15446	16	11	)	)	PUNCT
cet-15446	16	12	are	be	AUX
cet-15446	16	13	administered	administer	VERB
cet-15446	16	14	transdermally	transdermally	ADV
cet-15446	16	15	to	to	PART
cet-15446	16	16	obtain	obtain	VERB
cet-15446	16	17	a	a	DET
cet-15446	16	18	local	local	ADJ
cet-15446	16	19	action	action	NOUN
cet-15446	16	20	,	,	PUNCT
cet-15446	16	21	offering	offer	VERB
cet-15446	16	22	an	an	DET
cet-15446	16	23	alternative	alternative	NOUN
cet-15446	16	24	to	to	ADP
cet-15446	16	25	traditional	traditional	ADJ
cet-15446	16	26	oral	oral	ADJ
cet-15446	16	27	and	and	CCONJ
cet-15446	16	28	parental	parental	ADJ
cet-15446	16	29	administration	administration	NOUN
cet-15446	16	30	(	(	PUNCT
cet-15446	16	31	li	li	PROPN
cet-15446	16	32	et	et	PROPN
cet-15446	16	33	al	al	PROPN
cet-15446	16	34	.	.	PROPN
cet-15446	16	35	,	,	PUNCT
cet-15446	16	36	2007	2007	NUM
cet-15446	16	37	;	;	PUNCT
cet-15446	16	38	li	li	PROPN
cet-15446	16	39	et	et	PROPN
cet-15446	16	40	al	al	PROPN
cet-15446	16	41	.	.	PROPN
cet-15446	16	42	,	,	PUNCT
cet-15446	16	43	2012	2012	NUM
cet-15446	16	44	)	)	PUNCT
cet-15446	16	45	.	.	PUNCT
cet-15446	17	1	in	in	ADP
cet-15446	17	2	this	this	DET
cet-15446	17	3	way	way	NOUN
cet-15446	17	4	,	,	PUNCT
cet-15446	17	5	drugs	drug	NOUN
cet-15446	17	6	can	can	AUX
cet-15446	17	7	be	be	AUX
cet-15446	17	8	delivered	deliver	VERB
cet-15446	17	9	to	to	ADP
cet-15446	17	10	the	the	DET
cet-15446	17	11	action	action	NOUN
cet-15446	17	12	site	site	NOUN
cet-15446	17	13	,	,	PUNCT
cet-15446	17	14	minimizing	minimize	VERB
cet-15446	17	15	the	the	DET
cet-15446	17	16	common	common	ADJ
cet-15446	17	17	side	side	NOUN
cet-15446	17	18	effects	effect	NOUN
cet-15446	17	19	:	:	PUNCT
cet-15446	17	20	i.e.	i.e.	X
cet-15446	17	21	,	,	PUNCT
cet-15446	17	22	gastrointestinal	gastrointestinal	ADJ
cet-15446	17	23	irritation	irritation	NOUN
cet-15446	17	24	or	or	CCONJ
cet-15446	17	25	kidney	kidney	NOUN
cet-15446	17	26	damage	damage	NOUN
cet-15446	17	27	.	.	PUNCT
cet-15446	18	1	diclofenac	diclofenac	ADJ
cet-15446	18	2	sodium	sodium	NOUN
cet-15446	18	3	(	(	PUNCT
cet-15446	18	4	df	df	NOUN
cet-15446	18	5	)	)	PUNCT
cet-15446	18	6	is	be	AUX
cet-15446	18	7	an	an	DET
cet-15446	18	8	anti	anti	ADJ
cet-15446	18	9	-	-	ADJ
cet-15446	18	10	inflammatory	inflammatory	ADJ
cet-15446	18	11	drug	drug	NOUN
cet-15446	18	12	widely	widely	ADV
cet-15446	18	13	used	use	VERB
cet-15446	18	14	for	for	ADP
cet-15446	18	15	the	the	DET
cet-15446	18	16	treatment	treatment	NOUN
cet-15446	18	17	of	of	ADP
cet-15446	18	18	inflammatory	inflammatory	ADJ
cet-15446	18	19	and	and	CCONJ
cet-15446	18	20	degenerative	degenerative	ADJ
cet-15446	18	21	rheumatic	rheumatic	ADJ
cet-15446	18	22	conditions	condition	NOUN
cet-15446	18	23	,	,	PUNCT
cet-15446	18	24	post	post	ADJ
cet-15446	18	25	-	-	ADJ
cet-15446	18	26	traumatic	traumatic	ADJ
cet-15446	18	27	painful	painful	ADJ
cet-15446	18	28	states	state	NOUN
cet-15446	18	29	and	and	CCONJ
cet-15446	18	30	inflammation	inflammation	NOUN
cet-15446	18	31	(	(	PUNCT
cet-15446	18	32	devi	devi	PROPN
cet-15446	18	33	et	et	PROPN
cet-15446	18	34	al	al	PROPN
cet-15446	18	35	.	.	PROPN
cet-15446	18	36	,	,	PUNCT
cet-15446	18	37	2007	2007	NUM
cet-15446	18	38	)	)	PUNCT
cet-15446	18	39	.	.	PUNCT
cet-15446	19	1	however	however	ADV
cet-15446	19	2	,	,	PUNCT
cet-15446	19	3	its	its	PRON
cet-15446	19	4	skin	skin	NOUN
cet-15446	19	5	permeation	permeation	NOUN
cet-15446	19	6	is	be	AUX
cet-15446	19	7	limited	limit	VERB
cet-15446	19	8	by	by	ADP
cet-15446	19	9	its	its	PRON
cet-15446	19	10	poor	poor	ADJ
cet-15446	19	11	water	water	NOUN
cet-15446	19	12	solubility	solubility	NOUN
cet-15446	19	13	(	(	PUNCT
cet-15446	19	14	>	>	SYM
cet-15446	19	15	1	1	NUM
cet-15446	19	16	%	%	NOUN
cet-15446	19	17	)	)	PUNCT
cet-15446	19	18	and	and	CCONJ
cet-15446	19	19	the	the	DET
cet-15446	19	20	fast	fast	ADJ
cet-15446	19	21	clearance	clearance	NOUN
cet-15446	19	22	(	(	PUNCT
cet-15446	19	23	cevc	cevc	NOUN
cet-15446	19	24	and	and	CCONJ
cet-15446	19	25	blume	blume	PROPN
cet-15446	19	26	,	,	PUNCT
cet-15446	19	27	2001	2001	NUM
cet-15446	19	28	)	)	PUNCT
cet-15446	19	29	.	.	PUNCT
cet-15446	20	1	transfersomes	transfersome	NOUN
cet-15446	20	2	have	have	AUX
cet-15446	20	3	been	be	AUX
cet-15446	20	4	proposed	propose	VERB
cet-15446	20	5	by	by	ADP
cet-15446	20	6	some	some	DET
cet-15446	20	7	authors	author	NOUN
cet-15446	20	8	(	(	PUNCT
cet-15446	20	9	wadher	wadher	NOUN
cet-15446	20	10	et	et	PROPN
cet-15446	20	11	al	al	PROPN
cet-15446	20	12	.	.	PROPN
cet-15446	20	13	,	,	PUNCT
cet-15446	20	14	2024	2024	NUM
cet-15446	20	15	;	;	PUNCT
cet-15446	20	16	nagaich	nagaich	PRON
cet-15446	20	17	et	et	PROPN
cet-15446	20	18	al	al	PROPN
cet-15446	20	19	.	.	PROPN
cet-15446	20	20	,	,	PUNCT
cet-15446	20	21	2024	2024	NUM
cet-15446	20	22	):	):	PUNCT
cet-15446	20	23	more	more	ADV
cet-15446	20	24	specifically	specifically	ADV
cet-15446	20	25	,	,	PUNCT
cet-15446	20	26	ghanbarzadeh	ghanbarzadeh	NOUN
cet-15446	20	27	and	and	CCONJ
cet-15446	20	28	arami	arami	NOUN
cet-15446	20	29	(	(	PUNCT
cet-15446	20	30	2013	2013	NUM
cet-15446	20	31	)	)	PUNCT
cet-15446	20	32	produced	produce	VERB
cet-15446	20	33	transfersomes	transfersome	NOUN
cet-15446	20	34	loaded	load	VERB
cet-15446	20	35	with	with	ADP
cet-15446	20	36	diclofenac	diclofenac	NOUN
cet-15446	20	37	by	by	ADP
cet-15446	20	38	rotary	rotary	ADJ
cet-15446	20	39	evaporation	evaporation	NOUN
cet-15446	20	40	,	,	PUNCT
cet-15446	20	41	using	use	VERB
cet-15446	20	42	span	span	NOUN
cet-15446	20	43	80	80	NUM
cet-15446	20	44	as	as	ADP
cet-15446	20	45	surfactant	surfactant	ADJ
cet-15446	20	46	.	.	PUNCT
cet-15446	21	1	the	the	DET
cet-15446	21	2	lipidic	lipidic	ADJ
cet-15446	21	3	phase	phase	NOUN
cet-15446	21	4	composed	compose	VERB
cet-15446	21	5	of	of	ADP
cet-15446	21	6	phospholipids	phospholipid	NOUN
cet-15446	21	7	,	,	PUNCT
cet-15446	21	8	surfactant	surfactant	NOUN
cet-15446	21	9	and	and	CCONJ
cet-15446	21	10	cholesterol	cholesterol	NOUN
cet-15446	21	11	was	be	AUX
cet-15446	21	12	dissolved	dissolve	VERB
cet-15446	21	13	in	in	ADP
cet-15446	21	14	a	a	DET
cet-15446	21	15	chloroform	chloroform	NOUN
cet-15446	21	16	-	-	PUNCT
cet-15446	21	17	methanol	methanol	NOUN
cet-15446	21	18	mixture	mixture	NOUN
cet-15446	21	19	with	with	ADP
cet-15446	21	20	a	a	DET
cet-15446	21	21	volume	volume	NOUN
cet-15446	21	22	ratio	ratio	NOUN
cet-15446	21	23	of	of	ADP
cet-15446	21	24	3:1	3:1	NUM
cet-15446	21	25	.	.	PUNCT
cet-15446	22	1	the	the	DET
cet-15446	22	2	organic	organic	ADJ
cet-15446	22	3	solvent	solvent	NOUN
cet-15446	22	4	was	be	AUX
cet-15446	22	5	removed	remove	VERB
cet-15446	22	6	from	from	ADP
cet-15446	22	7	the	the	DET
cet-15446	22	8	lipidic	lipidic	ADJ
cet-15446	22	9	solution	solution	NOUN
cet-15446	22	10	by	by	ADP
cet-15446	22	11	using	use	VERB
cet-15446	22	12	rotary	rotary	ADJ
cet-15446	22	13	evaporation	evaporation	NOUN
cet-15446	22	14	at	at	ADP
cet-15446	22	15	45	45	NUM
cet-15446	22	16	°	°	NOUN
cet-15446	22	17	c	c	NOUN
cet-15446	22	18	and	and	CCONJ
cet-15446	22	19	reduced	reduced	ADJ
cet-15446	22	20	pressure	pressure	NOUN
cet-15446	22	21	.	.	PUNCT
cet-15446	23	1	the	the	DET
cet-15446	23	2	thin	thin	ADJ
cet-15446	23	3	film	film	NOUN
cet-15446	23	4	was	be	AUX
cet-15446	23	5	,	,	PUNCT
cet-15446	23	6	1171	1171	NUM
cet-15446	23	7	then	then	ADV
cet-15446	23	8	,	,	PUNCT
cet-15446	23	9	hydrated	hydrate	VERB
cet-15446	23	10	for	for	ADP
cet-15446	23	11	1	1	NUM
cet-15446	23	12	h	h	NOUN
cet-15446	23	13	with	with	ADP
cet-15446	23	14	an	an	DET
cet-15446	23	15	aqueous	aqueous	ADJ
cet-15446	23	16	solution	solution	NOUN
cet-15446	23	17	containing	contain	VERB
cet-15446	23	18	the	the	DET
cet-15446	23	19	drug	drug	NOUN
cet-15446	23	20	.	.	PUNCT
cet-15446	24	1	the	the	DET
cet-15446	24	2	resulted	resulted	ADJ
cet-15446	24	3	transfersomes	transfersome	NOUN
cet-15446	24	4	were	be	AUX
cet-15446	24	5	characterized	characterize	VERB
cet-15446	24	6	by	by	ADP
cet-15446	24	7	a	a	DET
cet-15446	24	8	mean	mean	ADJ
cet-15446	24	9	size	size	NOUN
cet-15446	24	10	of	of	ADP
cet-15446	24	11	426	426	NUM
cet-15446	24	12	±	±	NUM
cet-15446	24	13	33	33	NUM
cet-15446	24	14	nm	nm	NOUN
cet-15446	24	15	,	,	PUNCT
cet-15446	24	16	drastically	drastically	ADV
cet-15446	24	17	reduced	reduce	VERB
cet-15446	24	18	to	to	ADP
cet-15446	24	19	145	145	NUM
cet-15446	24	20	±	±	NUM
cet-15446	24	21	7	7	NUM
cet-15446	24	22	nm	nm	NOUN
cet-15446	24	23	after	after	ADP
cet-15446	24	24	several	several	ADJ
cet-15446	24	25	extrusion	extrusion	NOUN
cet-15446	24	26	steps	step	NOUN
cet-15446	24	27	.	.	PUNCT
cet-15446	25	1	the	the	DET
cet-15446	25	2	encapsulation	encapsulation	NOUN
cet-15446	25	3	efficiency	efficiency	NOUN
cet-15446	25	4	of	of	ADP
cet-15446	25	5	diclofenac	diclofenac	NOUN
cet-15446	25	6	loaded	load	VERB
cet-15446	25	7	into	into	ADP
cet-15446	25	8	transfersomes	transfersome	NOUN
cet-15446	25	9	was	be	AUX
cet-15446	25	10	equal	equal	ADJ
cet-15446	25	11	to	to	ADP
cet-15446	25	12	about	about	ADP
cet-15446	25	13	47	47	NUM
cet-15446	25	14	%	%	NOUN
cet-15446	25	15	.	.	PUNCT
cet-15446	26	1	sultana	sultana	NOUN
cet-15446	26	2	and	and	CCONJ
cet-15446	26	3	krishana	krishana	PROPN
cet-15446	26	4	sailaja	sailaja	PROPN
cet-15446	26	5	(	(	PUNCT
cet-15446	26	6	2015	2015	NUM
cet-15446	26	7	)	)	PUNCT
cet-15446	26	8	prepared	prepare	VERB
cet-15446	26	9	diclofenac	diclofenac	NOUN
cet-15446	26	10	sodium	sodium	NOUN
cet-15446	26	11	loaded	load	VERB
cet-15446	26	12	transfersomes	transfersome	NOUN
cet-15446	26	13	by	by	ADP
cet-15446	26	14	thin	thin	ADJ
cet-15446	26	15	film	film	NOUN
cet-15446	26	16	hydration	hydration	NOUN
cet-15446	26	17	,	,	PUNCT
cet-15446	26	18	testing	test	VERB
cet-15446	26	19	three	three	NUM
cet-15446	26	20	different	different	ADJ
cet-15446	26	21	surfactants	surfactant	NOUN
cet-15446	26	22	(	(	PUNCT
cet-15446	26	23	i.e.	i.e.	X
cet-15446	26	24	,	,	PUNCT
cet-15446	26	25	span	span	NOUN
cet-15446	26	26	20	20	NUM
cet-15446	26	27	,	,	PUNCT
cet-15446	26	28	span	span	VERB
cet-15446	26	29	60	60	NUM
cet-15446	26	30	,	,	PUNCT
cet-15446	26	31	and	and	CCONJ
cet-15446	26	32	span	span	VERB
cet-15446	26	33	80	80	NUM
cet-15446	26	34	)	)	PUNCT
cet-15446	26	35	as	as	ADP
cet-15446	26	36	edge	edge	NOUN
cet-15446	26	37	activators	activator	NOUN
cet-15446	26	38	.	.	PUNCT
cet-15446	27	1	the	the	DET
cet-15446	27	2	thin	thin	ADJ
cet-15446	27	3	film	film	NOUN
cet-15446	27	4	was	be	AUX
cet-15446	27	5	formed	form	VERB
cet-15446	27	6	after	after	ADP
cet-15446	27	7	rotary	rotary	ADJ
cet-15446	27	8	evaporation	evaporation	NOUN
cet-15446	27	9	at	at	ADP
cet-15446	27	10	25	25	NUM
cet-15446	27	11	°	°	NOUN
cet-15446	27	12	c	c	NOUN
cet-15446	27	13	and	and	CCONJ
cet-15446	27	14	600	600	NUM
cet-15446	27	15	mmhg	mmhg	NOUN
cet-15446	27	16	of	of	ADP
cet-15446	27	17	pressure	pressure	NOUN
cet-15446	27	18	,	,	PUNCT
cet-15446	27	19	using	use	VERB
cet-15446	27	20	a	a	DET
cet-15446	27	21	mixture	mixture	NOUN
cet-15446	27	22	of	of	ADP
cet-15446	27	23	chloroform	chloroform	NOUN
cet-15446	27	24	and	and	CCONJ
cet-15446	27	25	ethanol	ethanol	NOUN
cet-15446	27	26	for	for	ADP
cet-15446	27	27	the	the	DET
cet-15446	27	28	organic	organic	ADJ
cet-15446	27	29	phase	phase	NOUN
cet-15446	27	30	.	.	PUNCT
cet-15446	28	1	the	the	DET
cet-15446	28	2	best	good	ADJ
cet-15446	28	3	formulation	formulation	NOUN
cet-15446	28	4	was	be	AUX
cet-15446	28	5	obtained	obtain	VERB
cet-15446	28	6	using	use	VERB
cet-15446	28	7	soya	soya	NOUN
cet-15446	28	8	lecithin	lecithin	NOUN
cet-15446	28	9	and	and	CCONJ
cet-15446	28	10	span	span	NOUN
cet-15446	28	11	60	60	NUM
cet-15446	28	12	with	with	ADP
cet-15446	28	13	a	a	DET
cet-15446	28	14	2:1	2:1	NUM
cet-15446	28	15	mass	mass	NOUN
cet-15446	28	16	ratio	ratio	NOUN
cet-15446	28	17	,	,	PUNCT
cet-15446	28	18	resulting	result	VERB
cet-15446	28	19	in	in	ADP
cet-15446	28	20	the	the	DET
cet-15446	28	21	production	production	NOUN
cet-15446	28	22	of	of	ADP
cet-15446	28	23	vesicles	vesicle	NOUN
cet-15446	28	24	with	with	ADP
cet-15446	28	25	a	a	DET
cet-15446	28	26	mean	mean	ADJ
cet-15446	28	27	size	size	NOUN
cet-15446	28	28	of	of	ADP
cet-15446	28	29	257	257	NUM
cet-15446	28	30	nm	nm	NOUN
cet-15446	28	31	,	,	PUNCT
cet-15446	28	32	a	a	DET
cet-15446	28	33	zeta	zeta	NOUN
cet-15446	28	34	-	-	NOUN
cet-15446	28	35	potential	potential	NOUN
cet-15446	28	36	of	of	ADP
cet-15446	28	37	-25	-25	PUNCT
cet-15446	28	38	mv	mv	PROPN
cet-15446	28	39	and	and	CCONJ
cet-15446	28	40	a	a	DET
cet-15446	28	41	drug	drug	NOUN
cet-15446	28	42	encapsulation	encapsulation	NOUN
cet-15446	28	43	efficiency	efficiency	NOUN
cet-15446	28	44	equal	equal	ADJ
cet-15446	28	45	to	to	ADP
cet-15446	28	46	62	62	NUM
cet-15446	28	47	%	%	NOUN
cet-15446	28	48	.	.	PUNCT
cet-15446	29	1	the	the	DET
cet-15446	29	2	analysis	analysis	NOUN
cet-15446	29	3	of	of	ADP
cet-15446	29	4	the	the	DET
cet-15446	29	5	scientific	scientific	ADJ
cet-15446	29	6	literature	literature	NOUN
cet-15446	29	7	shows	show	VERB
cet-15446	29	8	that	that	SCONJ
cet-15446	29	9	conventional	conventional	ADJ
cet-15446	29	10	methods	method	NOUN
cet-15446	29	11	used	use	VERB
cet-15446	29	12	for	for	ADP
cet-15446	29	13	transfersomes	transfersome	NOUN
cet-15446	29	14	production	production	NOUN
cet-15446	29	15	suffer	suffer	VERB
cet-15446	29	16	from	from	ADP
cet-15446	29	17	several	several	ADJ
cet-15446	29	18	limitations	limitation	NOUN
cet-15446	29	19	,	,	PUNCT
cet-15446	29	20	resulting	result	VERB
cet-15446	29	21	in	in	ADP
cet-15446	29	22	the	the	DET
cet-15446	29	23	production	production	NOUN
cet-15446	29	24	of	of	ADP
cet-15446	29	25	micrometric	micrometric	ADJ
cet-15446	29	26	vesicles	vesicle	NOUN
cet-15446	29	27	,	,	PUNCT
cet-15446	29	28	with	with	ADP
cet-15446	29	29	low	low	ADJ
cet-15446	29	30	drug	drug	NOUN
cet-15446	29	31	encapsulation	encapsulation	NOUN
cet-15446	29	32	efficiency	efficiency	NOUN
cet-15446	29	33	and	and	CCONJ
cet-15446	29	34	high	high	ADJ
cet-15446	29	35	solvent	solvent	ADJ
cet-15446	29	36	residue	residue	NOUN
cet-15446	29	37	.	.	PUNCT
cet-15446	30	1	indeed	indeed	ADV
cet-15446	30	2	,	,	PUNCT
cet-15446	30	3	post	post	ADJ
cet-15446	30	4	-	-	ADJ
cet-15446	30	5	processing	processing	ADJ
cet-15446	30	6	operations	operation	NOUN
cet-15446	30	7	like	like	ADP
cet-15446	30	8	extrusion	extrusion	NOUN
cet-15446	30	9	and/or	and/or	CCONJ
cet-15446	30	10	solvent	solvent	NOUN
cet-15446	30	11	removal	removal	NOUN
cet-15446	30	12	were	be	AUX
cet-15446	30	13	necessary	necessary	ADJ
cet-15446	30	14	to	to	PART
cet-15446	30	15	obtain	obtain	VERB
cet-15446	30	16	nanometric	nanometric	ADJ
cet-15446	30	17	vesicles	vesicle	NOUN
cet-15446	30	18	with	with	ADP
cet-15446	30	19	low	low	ADJ
cet-15446	30	20	toxicity	toxicity	NOUN
cet-15446	30	21	.	.	PUNCT
cet-15446	31	1	an	an	DET
cet-15446	31	2	innovative	innovative	ADJ
cet-15446	31	3	and	and	CCONJ
cet-15446	31	4	continuous	continuous	ADJ
cet-15446	31	5	process	process	NOUN
cet-15446	31	6	assisted	assist	VERB
cet-15446	31	7	by	by	ADP
cet-15446	31	8	supercritical	supercritical	ADJ
cet-15446	31	9	carbon	carbon	NOUN
cet-15446	31	10	dioxide	dioxide	NOUN
cet-15446	31	11	(	(	PUNCT
cet-15446	31	12	sc	sc	NOUN
cet-15446	31	13	-	-	PUNCT
cet-15446	31	14	co2	co2	NOUN
cet-15446	31	15	)	)	PUNCT
cet-15446	31	16	,	,	PUNCT
cet-15446	31	17	named	name	VERB
cet-15446	31	18	supersomes	supersome	NOUN
cet-15446	31	19	,	,	PUNCT
cet-15446	31	20	can	can	AUX
cet-15446	31	21	be	be	AUX
cet-15446	31	22	used	use	VERB
cet-15446	31	23	to	to	PART
cet-15446	31	24	overcome	overcome	VERB
cet-15446	31	25	these	these	DET
cet-15446	31	26	limitations	limitation	NOUN
cet-15446	31	27	(	(	PUNCT
cet-15446	31	28	baldino	baldino	PROPN
cet-15446	31	29	and	and	CCONJ
cet-15446	31	30	reverchon	reverchon	PROPN
cet-15446	31	31	,	,	PUNCT
cet-15446	31	32	2022	2022	NUM
cet-15446	31	33	)	)	PUNCT
cet-15446	31	34	.	.	PUNCT
cet-15446	32	1	this	this	DET
cet-15446	32	2	process	process	NOUN
cet-15446	32	3	takes	take	VERB
cet-15446	32	4	advantage	advantage	NOUN
cet-15446	32	5	of	of	ADP
cet-15446	32	6	using	use	VERB
cet-15446	32	7	sc	sc	NOUN
cet-15446	32	8	-	-	PUNCT
cet-15446	32	9	co2	co2	NOUN
cet-15446	32	10	allowing	allow	VERB
cet-15446	32	11	the	the	DET
cet-15446	32	12	production	production	NOUN
cet-15446	32	13	of	of	ADP
cet-15446	32	14	stable	stable	ADJ
cet-15446	32	15	vesicles	vesicle	NOUN
cet-15446	32	16	with	with	ADP
cet-15446	32	17	nanometric	nanometric	ADJ
cet-15446	32	18	size	size	NOUN
cet-15446	32	19	,	,	PUNCT
cet-15446	32	20	unimodal	unimodal	ADJ
cet-15446	32	21	size	size	NOUN
cet-15446	32	22	distribution	distribution	NOUN
cet-15446	32	23	,	,	PUNCT
cet-15446	32	24	high	high	ADJ
cet-15446	32	25	drug	drug	NOUN
cet-15446	32	26	encapsulation	encapsulation	NOUN
cet-15446	32	27	efficiency	efficiency	NOUN
cet-15446	32	28	and	and	CCONJ
cet-15446	32	29	low	low	ADJ
cet-15446	32	30	solvent	solvent	ADJ
cet-15446	32	31	residue	residue	NOUN
cet-15446	32	32	(	(	PUNCT
cet-15446	32	33	trucillo	trucillo	NOUN
cet-15446	32	34	et	et	PROPN
cet-15446	32	35	al	al	PROPN
cet-15446	32	36	.	.	PROPN
cet-15446	32	37	,	,	PUNCT
cet-15446	32	38	2020	2020	NUM
cet-15446	32	39	)	)	PUNCT
cet-15446	32	40	.	.	PUNCT
cet-15446	33	1	in	in	ADP
cet-15446	33	2	this	this	DET
cet-15446	33	3	work	work	NOUN
cet-15446	33	4	,	,	PUNCT
cet-15446	33	5	supersomes	supersome	NOUN
cet-15446	33	6	was	be	AUX
cet-15446	33	7	used	use	VERB
cet-15446	33	8	to	to	PART
cet-15446	33	9	produce	produce	VERB
cet-15446	33	10	transfersomes	transfersome	NOUN
cet-15446	33	11	,	,	PUNCT
cet-15446	33	12	selecting	select	VERB
cet-15446	33	13	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	33	14	as	as	ADP
cet-15446	33	15	phospholipid	phospholipid	NOUN
cet-15446	33	16	and	and	CCONJ
cet-15446	33	17	span	span	NOUN
cet-15446	33	18	80	80	NUM
cet-15446	33	19	as	as	ADP
cet-15446	33	20	edge	edge	NOUN
cet-15446	33	21	activator	activator	NOUN
cet-15446	33	22	(	(	PUNCT
cet-15446	33	23	squittieri	squittieri	PROPN
cet-15446	33	24	et	et	PROPN
cet-15446	33	25	al	al	PROPN
cet-15446	33	26	.	.	PROPN
cet-15446	33	27	,	,	PUNCT
cet-15446	33	28	2023	2023	NUM
cet-15446	33	29	)	)	PUNCT
cet-15446	33	30	.	.	PUNCT
cet-15446	34	1	transfersomes	transfersome	NOUN
cet-15446	34	2	with	with	ADP
cet-15446	34	3	an	an	DET
cet-15446	34	4	increasing	increase	VERB
cet-15446	34	5	amount	amount	NOUN
cet-15446	34	6	of	of	ADP
cet-15446	34	7	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	34	8	(	(	PUNCT
cet-15446	34	9	i.e.	i.e.	X
cet-15446	34	10	,	,	PUNCT
cet-15446	34	11	from	from	ADP
cet-15446	34	12	500	500	NUM
cet-15446	34	13	to	to	PART
cet-15446	34	14	2000	2000	NUM
cet-15446	34	15	mg	mg	NUM
cet-15446	34	16	)	)	PUNCT
cet-15446	34	17	were	be	AUX
cet-15446	34	18	produced	produce	VERB
cet-15446	34	19	to	to	PART
cet-15446	34	20	identify	identify	VERB
cet-15446	34	21	the	the	DET
cet-15446	34	22	best	good	ADJ
cet-15446	34	23	formulation	formulation	NOUN
cet-15446	34	24	to	to	PART
cet-15446	34	25	obtain	obtain	VERB
cet-15446	34	26	stable	stable	ADJ
cet-15446	34	27	transferosomes	transferosome	NOUN
cet-15446	34	28	.	.	PUNCT
cet-15446	35	1	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	35	2	to	to	PART
cet-15446	35	3	span	span	VERB
cet-15446	35	4	80	80	NUM
cet-15446	35	5	weight	weight	NOUN
cet-15446	35	6	ratio	ratio	NOUN
cet-15446	35	7	was	be	AUX
cet-15446	35	8	set	set	VERB
cet-15446	35	9	at	at	ADP
cet-15446	35	10	80:20	80:20	NUM
cet-15446	35	11	,	,	PUNCT
cet-15446	35	12	since	since	SCONJ
cet-15446	35	13	this	this	DET
cet-15446	35	14	value	value	NOUN
cet-15446	35	15	allows	allow	VERB
cet-15446	35	16	to	to	ADP
cet-15446	35	17	the	the	DET
cet-15446	35	18	production	production	NOUN
cet-15446	35	19	of	of	ADP
cet-15446	35	20	nanometric	nanometric	ADJ
cet-15446	35	21	and	and	CCONJ
cet-15446	35	22	stable	stable	ADJ
cet-15446	35	23	transfersomes	transfersome	NOUN
cet-15446	35	24	,	,	PUNCT
cet-15446	35	25	as	as	SCONJ
cet-15446	35	26	reported	report	VERB
cet-15446	35	27	in	in	ADP
cet-15446	35	28	a	a	DET
cet-15446	35	29	previous	previous	ADJ
cet-15446	35	30	work	work	NOUN
cet-15446	35	31	(	(	PUNCT
cet-15446	35	32	squittieri	squittieri	PROPN
cet-15446	35	33	et	et	PROPN
cet-15446	35	34	al	al	PROPN
cet-15446	35	35	.	.	PROPN
cet-15446	35	36	,	,	PUNCT
cet-15446	35	37	2023	2023	NUM
cet-15446	35	38	)	)	PUNCT
cet-15446	35	39	.	.	PUNCT
cet-15446	36	1	the	the	DET
cet-15446	36	2	best	good	ADJ
cet-15446	36	3	formulation	formulation	NOUN
cet-15446	36	4	obtained	obtain	VERB
cet-15446	36	5	for	for	ADP
cet-15446	36	6	the	the	DET
cet-15446	36	7	production	production	NOUN
cet-15446	36	8	of	of	ADP
cet-15446	36	9	empty	empty	ADJ
cet-15446	36	10	transfersomes	transfersome	NOUN
cet-15446	36	11	was	be	AUX
cet-15446	36	12	,	,	PUNCT
cet-15446	36	13	then	then	ADV
cet-15446	36	14	,	,	PUNCT
cet-15446	36	15	tested	test	VERB
cet-15446	36	16	to	to	PART
cet-15446	36	17	encapsulate	encapsulate	VERB
cet-15446	36	18	diclofenac	diclofenac	ADJ
cet-15446	36	19	sodium	sodium	NOUN
cet-15446	36	20	;	;	PUNCT
cet-15446	36	21	analyses	analysis	NOUN
cet-15446	36	22	of	of	ADP
cet-15446	36	23	drug	drug	NOUN
cet-15446	36	24	encapsulation	encapsulation	NOUN
cet-15446	36	25	efficiency	efficiency	NOUN
cet-15446	36	26	and	and	CCONJ
cet-15446	36	27	drug	drug	NOUN
cet-15446	36	28	release	release	NOUN
cet-15446	36	29	were	be	AUX
cet-15446	36	30	carried	carry	VERB
cet-15446	36	31	out	out	ADP
cet-15446	36	32	to	to	PART
cet-15446	36	33	understand	understand	VERB
cet-15446	36	34	how	how	SCONJ
cet-15446	36	35	the	the	DET
cet-15446	36	36	encapsulation	encapsulation	NOUN
cet-15446	36	37	of	of	ADP
cet-15446	36	38	df	df	PROPN
cet-15446	36	39	affected	affect	VERB
cet-15446	36	40	its	its	PRON
cet-15446	36	41	kinetic	kinetic	ADJ
cet-15446	36	42	release	release	NOUN
cet-15446	36	43	.	.	PUNCT
cet-15446	37	1	2	2	X
cet-15446	37	2	.	.	X
cet-15446	37	3	materials	material	NOUN
cet-15446	37	4	and	and	CCONJ
cet-15446	37	5	methods	method	NOUN
cet-15446	37	6	2.1	2.1	NUM
cet-15446	37	7	materials	material	NOUN
cet-15446	37	8	l	l	NOUN
cet-15446	37	9	-	-	PUNCT
cet-15446	37	10	α	α	NOUN
cet-15446	37	11	-	-	NOUN
cet-15446	37	12	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	37	13	from	from	ADP
cet-15446	37	14	egg	egg	NOUN
cet-15446	37	15	yolk	yolk	NOUN
cet-15446	37	16	(	(	PUNCT
cet-15446	37	17	pc	pc	NOUN
cet-15446	37	18	,	,	PUNCT
cet-15446	37	19	purity	purity	NOUN
cet-15446	37	20	≥99	≥99	NUM
cet-15446	37	21	%	%	NOUN
cet-15446	37	22	)	)	PUNCT
cet-15446	37	23	,	,	PUNCT
cet-15446	37	24	span	span	VERB
cet-15446	37	25	80	80	NUM
cet-15446	37	26	(	(	PUNCT
cet-15446	37	27	mw=	mw=	NOUN
cet-15446	37	28	428.60	428.60	NUM
cet-15446	37	29	g	g	NOUN
cet-15446	37	30	/	/	SYM
cet-15446	37	31	mol	mol	NOUN
cet-15446	37	32	)	)	PUNCT
cet-15446	37	33	,	,	PUNCT
cet-15446	37	34	diclofenac	diclofenac	NOUN
cet-15446	37	35	sodium	sodium	NOUN
cet-15446	37	36	(	(	PUNCT
cet-15446	37	37	df	df	NOUN
cet-15446	37	38	,	,	PUNCT
cet-15446	37	39	mw=	mw=	NOUN
cet-15446	37	40	318.13	318.13	NUM
cet-15446	37	41	g	g	NOUN
cet-15446	37	42	/	/	SYM
cet-15446	37	43	mol	mol	NOUN
cet-15446	37	44	)	)	PUNCT
cet-15446	37	45	were	be	AUX
cet-15446	37	46	purchased	purchase	VERB
cet-15446	37	47	from	from	ADP
cet-15446	37	48	sigma	sigma	PROPN
cet-15446	37	49	aldrich	aldrich	PROPN
cet-15446	37	50	(	(	PUNCT
cet-15446	37	51	milan	milan	PROPN
cet-15446	37	52	,	,	PUNCT
cet-15446	37	53	italy	italy	PROPN
cet-15446	37	54	)	)	PUNCT
cet-15446	37	55	.	.	PUNCT
cet-15446	38	1	ethanol	ethanol	NOUN
cet-15446	38	2	(	(	PUNCT
cet-15446	38	3	anhydrous	anhydrous	ADJ
cet-15446	38	4	,	,	PUNCT
cet-15446	38	5	purity	purity	NOUN
cet-15446	38	6	≥99	≥99	NUM
cet-15446	38	7	%	%	NOUN
cet-15446	38	8	)	)	PUNCT
cet-15446	38	9	was	be	AUX
cet-15446	38	10	purchased	purchase	VERB
cet-15446	38	11	from	from	ADP
cet-15446	38	12	carlo	carlo	PROPN
cet-15446	38	13	erba	erba	NOUN
cet-15446	38	14	reagents	reagent	NOUN
cet-15446	38	15	(	(	PUNCT
cet-15446	38	16	cornaredo	cornaredo	X
cet-15446	38	17	(	(	PUNCT
cet-15446	38	18	mi	mi	NOUN
cet-15446	38	19	)	)	PUNCT
cet-15446	38	20	,	,	PUNCT
cet-15446	38	21	italy	italy	PROPN
cet-15446	38	22	)	)	PUNCT
cet-15446	38	23	.	.	PUNCT
cet-15446	39	1	carbon	carbon	NOUN
cet-15446	39	2	dioxide	dioxide	NOUN
cet-15446	39	3	(	(	PUNCT
cet-15446	39	4	co2	co2	NOUN
cet-15446	39	5	,	,	PUNCT
cet-15446	39	6	purity	purity	NOUN
cet-15446	39	7	˃99.4	˃99.4	PROPN
cet-15446	39	8	%	%	NOUN
cet-15446	39	9	)	)	PUNCT
cet-15446	39	10	was	be	AUX
cet-15446	39	11	purchased	purchase	VERB
cet-15446	39	12	from	from	ADP
cet-15446	39	13	morlando	morlando	PROPN
cet-15446	39	14	group	group	PROPN
cet-15446	39	15	srl	srl	PROPN
cet-15446	39	16	(	(	PUNCT
cet-15446	39	17	naples	naples	PROPN
cet-15446	39	18	,	,	PUNCT
cet-15446	39	19	italy	italy	PROPN
cet-15446	39	20	)	)	PUNCT
cet-15446	39	21	.	.	PUNCT
cet-15446	40	1	2.2	2.2	NUM
cet-15446	40	2	transfersome	transfersome	NOUN
cet-15446	40	3	formulation	formulation	NOUN
cet-15446	40	4	a	a	DET
cet-15446	40	5	100	100	NUM
cet-15446	40	6	ml	ml	NOUN
cet-15446	40	7	volume	volume	NOUN
cet-15446	40	8	of	of	ADP
cet-15446	40	9	ethanolic	ethanolic	ADJ
cet-15446	40	10	solution	solution	NOUN
cet-15446	40	11	containing	contain	VERB
cet-15446	40	12	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	40	13	and	and	CCONJ
cet-15446	40	14	span	span	VERB
cet-15446	40	15	80	80	NUM
cet-15446	40	16	at	at	ADP
cet-15446	40	17	different	different	ADJ
cet-15446	40	18	amounts	amount	NOUN
cet-15446	40	19	of	of	ADP
cet-15446	40	20	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	40	21	(	(	PUNCT
cet-15446	40	22	ranging	range	VERB
cet-15446	40	23	from	from	ADP
cet-15446	40	24	500	500	NUM
cet-15446	40	25	to	to	ADP
cet-15446	40	26	2000	2000	NUM
cet-15446	40	27	mg	mg	NUM
cet-15446	40	28	)	)	PUNCT
cet-15446	40	29	was	be	AUX
cet-15446	40	30	prepared	prepare	VERB
cet-15446	40	31	by	by	ADP
cet-15446	40	32	magnetic	magnetic	ADJ
cet-15446	40	33	stirring	stirring	NOUN
cet-15446	40	34	at	at	ADP
cet-15446	40	35	250	250	NUM
cet-15446	40	36	rpm	rpm	NOUN
cet-15446	40	37	for	for	ADP
cet-15446	40	38	1	1	NUM
cet-15446	40	39	h	h	NOUN
cet-15446	40	40	and	and	CCONJ
cet-15446	40	41	at	at	ADP
cet-15446	40	42	room	room	NOUN
cet-15446	40	43	temperature	temperature	NOUN
cet-15446	40	44	.	.	PUNCT
cet-15446	41	1	for	for	ADP
cet-15446	41	2	all	all	DET
cet-15446	41	3	the	the	DET
cet-15446	41	4	experiments	experiment	NOUN
cet-15446	41	5	,	,	PUNCT
cet-15446	41	6	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	41	7	to	to	PART
cet-15446	41	8	span	span	VERB
cet-15446	41	9	80	80	NUM
cet-15446	41	10	weight	weight	NOUN
cet-15446	41	11	ratio	ratio	NOUN
cet-15446	41	12	was	be	AUX
cet-15446	41	13	fixed	fix	VERB
cet-15446	41	14	at	at	ADP
cet-15446	41	15	80:20	80:20	NUM
cet-15446	41	16	.	.	PUNCT
cet-15446	42	1	the	the	DET
cet-15446	42	2	aqueous	aqueous	ADJ
cet-15446	42	3	solution	solution	NOUN
cet-15446	42	4	was	be	AUX
cet-15446	42	5	obtained	obtain	VERB
cet-15446	42	6	by	by	ADP
cet-15446	42	7	dissolving	dissolve	VERB
cet-15446	42	8	10	10	NUM
cet-15446	42	9	mg	mg	NOUN
cet-15446	42	10	of	of	ADP
cet-15446	42	11	diclofenac	diclofenac	NOUN
cet-15446	42	12	in	in	ADP
cet-15446	42	13	200	200	NUM
cet-15446	42	14	ml	ml	NOUN
cet-15446	42	15	of	of	ADP
cet-15446	42	16	water	water	NOUN
cet-15446	42	17	at	at	ADP
cet-15446	42	18	a	a	DET
cet-15446	42	19	concentration	concentration	NOUN
cet-15446	42	20	of	of	ADP
cet-15446	42	21	0.05	0.05	NUM
cet-15446	42	22	mg	mg	NUM
cet-15446	42	23	/	/	SYM
cet-15446	42	24	ml	ml	NOUN
cet-15446	42	25	;	;	PUNCT
cet-15446	42	26	this	this	DET
cet-15446	42	27	solution	solution	NOUN
cet-15446	42	28	was	be	AUX
cet-15446	42	29	stirred	stir	VERB
cet-15446	42	30	at	at	ADP
cet-15446	42	31	250	250	NUM
cet-15446	42	32	rpm	rpm	NOUN
cet-15446	42	33	for	for	ADP
cet-15446	42	34	1	1	NUM
cet-15446	42	35	h	h	NOUN
cet-15446	42	36	at	at	ADP
cet-15446	42	37	room	room	NOUN
cet-15446	42	38	temperature	temperature	NOUN
cet-15446	42	39	.	.	PUNCT
cet-15446	43	1	2.3	2.3	NUM
cet-15446	43	2	supersomes	supersome	NOUN
cet-15446	43	3	plant	plant	NOUN
cet-15446	43	4	description	description	NOUN
cet-15446	43	5	supersomes	supersome	NOUN
cet-15446	43	6	is	be	AUX
cet-15446	43	7	a	a	DET
cet-15446	43	8	high	high	ADJ
cet-15446	43	9	-	-	PUNCT
cet-15446	43	10	pressure	pressure	NOUN
cet-15446	43	11	plant	plant	NOUN
cet-15446	43	12	mainly	mainly	ADV
cet-15446	43	13	composed	compose	VERB
cet-15446	43	14	of	of	ADP
cet-15446	43	15	a	a	DET
cet-15446	43	16	static	static	ADJ
cet-15446	43	17	mixer	mixer	NOUN
cet-15446	43	18	(	(	PUNCT
cet-15446	43	19	with	with	ADP
cet-15446	43	20	an	an	DET
cet-15446	43	21	internal	internal	ADJ
cet-15446	43	22	volume	volume	NOUN
cet-15446	43	23	of	of	ADP
cet-15446	43	24	150	150	NUM
cet-15446	43	25	cm3	cm3	NOUN
cet-15446	43	26	)	)	PUNCT
cet-15446	43	27	,	,	PUNCT
cet-15446	43	28	filled	fill	VERB
cet-15446	43	29	with	with	ADP
cet-15446	43	30	stainless	stainless	ADJ
cet-15446	43	31	-	-	PUNCT
cet-15446	43	32	steel	steel	NOUN
cet-15446	43	33	packings	packing	NOUN
cet-15446	43	34	and	and	CCONJ
cet-15446	43	35	a	a	DET
cet-15446	43	36	formation	formation	NOUN
cet-15446	43	37	chamber	chamber	NOUN
cet-15446	43	38	(	(	PUNCT
cet-15446	43	39	with	with	ADP
cet-15446	43	40	an	an	DET
cet-15446	43	41	internal	internal	ADJ
cet-15446	43	42	volume	volume	NOUN
cet-15446	43	43	of	of	ADP
cet-15446	43	44	500	500	NUM
cet-15446	43	45	cm3	cm3	NOUN
cet-15446	43	46	)	)	PUNCT
cet-15446	43	47	,	,	PUNCT
cet-15446	43	48	both	both	PRON
cet-15446	43	49	operating	operate	VERB
cet-15446	43	50	at	at	ADP
cet-15446	43	51	40	40	NUM
cet-15446	43	52	°	°	NOUN
cet-15446	43	53	c	c	NOUN
cet-15446	43	54	and	and	CCONJ
cet-15446	43	55	100	100	NUM
cet-15446	43	56	bar	bar	NOUN
cet-15446	43	57	.	.	PUNCT
cet-15446	44	1	supercritical	supercritical	ADJ
cet-15446	44	2	carbon	carbon	NOUN
cet-15446	44	3	dioxide	dioxide	NOUN
cet-15446	44	4	and	and	CCONJ
cet-15446	44	5	the	the	DET
cet-15446	44	6	ethanolic	ethanolic	ADJ
cet-15446	44	7	solution	solution	NOUN
cet-15446	44	8	are	be	AUX
cet-15446	44	9	pumped	pump	VERB
cet-15446	44	10	into	into	ADP
cet-15446	44	11	the	the	DET
cet-15446	44	12	static	static	ADJ
cet-15446	44	13	mixer	mixer	NOUN
cet-15446	44	14	by	by	ADP
cet-15446	44	15	using	use	VERB
cet-15446	44	16	an	an	DET
cet-15446	44	17	ecoflow	ecoflow	ADJ
cet-15446	44	18	®	®	NOUN
cet-15446	44	19	pump	pump	NOUN
cet-15446	44	20	(	(	PUNCT
cet-15446	44	21	mod	mod	PROPN
cet-15446	44	22	.	.	PROPN
cet-15446	44	23	ldc	ldc	PROPN
cet-15446	44	24	-	-	PUNCT
cet-15446	44	25	m-2	m-2	PROPN
cet-15446	44	26	lewa	lewa	PROPN
cet-15446	44	27	,	,	PUNCT
cet-15446	44	28	leonberg	leonberg	PROPN
cet-15446	44	29	,	,	PUNCT
cet-15446	44	30	germany	germany	PROPN
cet-15446	44	31	)	)	PUNCT
cet-15446	44	32	and	and	CCONJ
cet-15446	44	33	a	a	DET
cet-15446	44	34	gilson	gilson	NOUN
cet-15446	44	35	pump	pump	NOUN
cet-15446	44	36	(	(	PUNCT
cet-15446	44	37	mod	mod	PROPN
cet-15446	44	38	.	.	PROPN
cet-15446	44	39	305	305	NUM
cet-15446	44	40	,	,	PUNCT
cet-15446	44	41	villiers	villier	NOUN
cet-15446	44	42	le	le	X
cet-15446	44	43	bel	bel	PROPN
cet-15446	44	44	,	,	PUNCT
cet-15446	44	45	france	france	PROPN
cet-15446	44	46	)	)	PUNCT
cet-15446	44	47	,	,	PUNCT
cet-15446	44	48	respectively	respectively	ADV
cet-15446	44	49	.	.	PUNCT
cet-15446	45	1	their	their	PRON
cet-15446	45	2	interaction	interaction	NOUN
cet-15446	45	3	promotes	promote	VERB
cet-15446	45	4	the	the	DET
cet-15446	45	5	formation	formation	NOUN
cet-15446	45	6	of	of	ADP
cet-15446	45	7	a	a	DET
cet-15446	45	8	gas	gas	NOUN
cet-15446	45	9	-	-	PUNCT
cet-15446	45	10	expanded	expand	VERB
cet-15446	45	11	liquid	liquid	NOUN
cet-15446	45	12	,	,	PUNCT
cet-15446	45	13	which	which	PRON
cet-15446	45	14	is	be	AUX
cet-15446	45	15	,	,	PUNCT
cet-15446	45	16	then	then	ADV
cet-15446	45	17	,	,	PUNCT
cet-15446	45	18	transferred	transfer	VERB
cet-15446	45	19	through	through	ADP
cet-15446	45	20	a	a	DET
cet-15446	45	21	capillary	capillary	ADJ
cet-15446	45	22	tube	tube	NOUN
cet-15446	45	23	inside	inside	ADP
cet-15446	45	24	the	the	DET
cet-15446	45	25	formation	formation	NOUN
cet-15446	45	26	chamber	chamber	NOUN
cet-15446	45	27	.	.	PUNCT
cet-15446	46	1	the	the	DET
cet-15446	46	2	aqueous	aqueous	ADJ
cet-15446	46	3	solution	solution	NOUN
cet-15446	46	4	is	be	AUX
cet-15446	46	5	pumped	pump	VERB
cet-15446	46	6	into	into	ADP
cet-15446	46	7	the	the	DET
cet-15446	46	8	formation	formation	NOUN
cet-15446	46	9	chamber	chamber	NOUN
cet-15446	46	10	by	by	ADP
cet-15446	46	11	a	a	DET
cet-15446	46	12	gilson	gilson	PROPN
cet-15446	46	13	pump	pump	NOUN
cet-15446	46	14	(	(	PUNCT
cet-15446	46	15	mod	mod	PROPN
cet-15446	46	16	.	.	PROPN
cet-15446	46	17	305	305	NUM
cet-15446	46	18	,	,	PUNCT
cet-15446	46	19	villiers	villier	NOUN
cet-15446	46	20	le	le	X
cet-15446	46	21	bel	bel	PROPN
cet-15446	46	22	,	,	PUNCT
cet-15446	46	23	france	france	PROPN
cet-15446	46	24	)	)	PUNCT
cet-15446	46	25	and	and	CCONJ
cet-15446	46	26	atomized	atomize	VERB
cet-15446	46	27	through	through	ADP
cet-15446	46	28	a	a	DET
cet-15446	46	29	nozzle	nozzle	NOUN
cet-15446	46	30	with	with	ADP
cet-15446	46	31	an	an	DET
cet-15446	46	32	internal	internal	ADJ
cet-15446	46	33	diameter	diameter	NOUN
cet-15446	46	34	of	of	ADP
cet-15446	46	35	80	80	NUM
cet-15446	46	36	µm	µm	NOUN
cet-15446	46	37	.	.	PUNCT
cet-15446	47	1	at	at	ADP
cet-15446	47	2	the	the	DET
cet-15446	47	3	end	end	NOUN
cet-15446	47	4	of	of	ADP
cet-15446	47	5	the	the	DET
cet-15446	47	6	process	process	NOUN
cet-15446	47	7	,	,	PUNCT
cet-15446	47	8	the	the	DET
cet-15446	47	9	ethanol	ethanol	NOUN
cet-15446	47	10	-	-	PUNCT
cet-15446	47	11	co2	co2	NOUN
cet-15446	47	12	mixture	mixture	NOUN
cet-15446	47	13	is	be	AUX
cet-15446	47	14	recovered	recover	VERB
cet-15446	47	15	by	by	ADP
cet-15446	47	16	a	a	DET
cet-15446	47	17	separator	separator	NOUN
cet-15446	47	18	,	,	PUNCT
cet-15446	47	19	operating	operate	VERB
cet-15446	47	20	at	at	ADP
cet-15446	47	21	25	25	NUM
cet-15446	47	22	°	°	NOUN
cet-15446	47	23	c	c	NOUN
cet-15446	47	24	and	and	CCONJ
cet-15446	47	25	10	10	NUM
cet-15446	47	26	bar	bar	NOUN
cet-15446	47	27	;	;	PUNCT
cet-15446	47	28	transfersomes	transfersome	NOUN
cet-15446	47	29	suspension	suspension	NOUN
cet-15446	47	30	is	be	AUX
cet-15446	47	31	instead	instead	ADV
cet-15446	47	32	collected	collect	VERB
cet-15446	47	33	in	in	ADP
cet-15446	47	34	a	a	DET
cet-15446	47	35	reservoir	reservoir	NOUN
cet-15446	47	36	located	locate	VERB
cet-15446	47	37	downstream	downstream	NOUN
cet-15446	47	38	of	of	ADP
cet-15446	47	39	the	the	DET
cet-15446	47	40	formation	formation	NOUN
cet-15446	47	41	chamber	chamber	NOUN
cet-15446	47	42	and	and	CCONJ
cet-15446	47	43	recovered	recover	VERB
cet-15446	47	44	by	by	ADP
cet-15446	47	45	an	an	DET
cet-15446	47	46	on	on	ADP
cet-15446	47	47	/	/	SYM
cet-15446	47	48	off	off	ADP
cet-15446	47	49	valve	valve	NOUN
cet-15446	47	50	.	.	PUNCT
cet-15446	48	1	temperature	temperature	NOUN
cet-15446	48	2	is	be	AUX
cet-15446	48	3	controlled	control	VERB
cet-15446	48	4	by	by	ADP
cet-15446	48	5	using	use	VERB
cet-15446	48	6	a	a	DET
cet-15446	48	7	j	j	NOUN
cet-15446	48	8	-	-	PUNCT
cet-15446	48	9	type	type	NOUN
cet-15446	48	10	thermocouple	thermocouple	NOUN
cet-15446	48	11	and	and	CCONJ
cet-15446	48	12	regulated	regulate	VERB
cet-15446	48	13	with	with	ADP
cet-15446	48	14	pid	pid	NOUN
cet-15446	48	15	controllers	controller	NOUN
cet-15446	48	16	;	;	PUNCT
cet-15446	48	17	whereas	whereas	SCONJ
cet-15446	48	18	pressure	pressure	NOUN
cet-15446	48	19	is	be	AUX
cet-15446	48	20	measured	measure	VERB
cet-15446	48	21	by	by	ADP
cet-15446	48	22	using	use	VERB
cet-15446	48	23	a	a	DET
cet-15446	48	24	pressure	pressure	NOUN
cet-15446	48	25	gauge	gauge	NOUN
cet-15446	48	26	.	.	PUNCT
cet-15446	49	1	further	further	ADJ
cet-15446	49	2	details	detail	NOUN
cet-15446	49	3	about	about	ADP
cet-15446	49	4	supersomes	supersome	NOUN
cet-15446	49	5	plant	plant	NOUN
cet-15446	49	6	and	and	CCONJ
cet-15446	49	7	the	the	DET
cet-15446	49	8	mechanism	mechanism	NOUN
cet-15446	49	9	of	of	ADP
cet-15446	49	10	transfersomes	transfersome	NOUN
cet-15446	49	11	formation	formation	NOUN
cet-15446	49	12	can	can	AUX
cet-15446	49	13	be	be	AUX
cet-15446	49	14	found	find	VERB
cet-15446	49	15	in	in	ADP
cet-15446	49	16	previous	previous	ADJ
cet-15446	49	17	works	work	NOUN
cet-15446	49	18	(	(	PUNCT
cet-15446	49	19	baldino	baldino	PROPN
cet-15446	49	20	and	and	CCONJ
cet-15446	49	21	reverchon	reverchon	PROPN
cet-15446	49	22	,	,	PUNCT
cet-15446	49	23	2022	2022	NUM
cet-15446	49	24	)	)	PUNCT
cet-15446	49	25	.	.	PUNCT
cet-15446	50	1	1172	1172	NUM
cet-15446	50	2	2.4	2.4	NUM
cet-15446	50	3	characterization	characterization	NOUN
cet-15446	50	4	techniques	technique	NOUN
cet-15446	50	5	the	the	DET
cet-15446	50	6	mean	mean	ADJ
cet-15446	50	7	hydrodynamic	hydrodynamic	ADJ
cet-15446	50	8	diameter	diameter	NOUN
cet-15446	50	9	(	(	PUNCT
cet-15446	50	10	mhd	mhd	NOUN
cet-15446	50	11	)	)	PUNCT
cet-15446	50	12	,	,	PUNCT
cet-15446	50	13	polydispersity	polydispersity	NOUN
cet-15446	50	14	index	index	NOUN
cet-15446	50	15	(	(	PUNCT
cet-15446	50	16	pdi	pdi	PROPN
cet-15446	50	17	)	)	PUNCT
cet-15446	50	18	and	and	CCONJ
cet-15446	50	19	zeta	zeta	NOUN
cet-15446	50	20	-	-	PUNCT
cet-15446	50	21	potential	potential	ADJ
cet-15446	50	22	values	value	NOUN
cet-15446	50	23	of	of	ADP
cet-15446	50	24	transfersomes	transfersome	NOUN
cet-15446	50	25	were	be	AUX
cet-15446	50	26	measured	measure	VERB
cet-15446	50	27	by	by	ADP
cet-15446	50	28	using	use	VERB
cet-15446	50	29	a	a	DET
cet-15446	50	30	dynamic	dynamic	ADJ
cet-15446	50	31	light	light	NOUN
cet-15446	50	32	scattering	scattering	NOUN
cet-15446	50	33	(	(	PUNCT
cet-15446	50	34	dls	dls	PROPN
cet-15446	50	35	,	,	PUNCT
cet-15446	50	36	mod	mod	PROPN
cet-15446	50	37	.	.	PROPN
cet-15446	50	38	zetasizer	zetasizer	PROPN
cet-15446	50	39	nano	nano	PROPN
cet-15446	50	40	s	s	PART
cet-15446	50	41	)	)	PUNCT
cet-15446	50	42	.	.	PUNCT
cet-15446	51	1	all	all	DET
cet-15446	51	2	measurements	measurement	NOUN
cet-15446	51	3	were	be	AUX
cet-15446	51	4	performed	perform	VERB
cet-15446	51	5	in	in	ADP
cet-15446	51	6	triplicate	triplicate	NOUN
cet-15446	51	7	and	and	CCONJ
cet-15446	51	8	at	at	ADP
cet-15446	51	9	different	different	ADJ
cet-15446	51	10	intervals	interval	NOUN
cet-15446	51	11	of	of	ADP
cet-15446	51	12	time	time	NOUN
cet-15446	51	13	(	(	PUNCT
cet-15446	51	14	i.e.	i.e.	X
cet-15446	51	15	,	,	PUNCT
cet-15446	51	16	15	15	NUM
cet-15446	51	17	and	and	CCONJ
cet-15446	51	18	30	30	NUM
cet-15446	51	19	days	day	NOUN
cet-15446	51	20	after	after	ADP
cet-15446	51	21	the	the	DET
cet-15446	51	22	production	production	NOUN
cet-15446	51	23	)	)	PUNCT
cet-15446	51	24	to	to	PART
cet-15446	51	25	study	study	VERB
cet-15446	51	26	the	the	DET
cet-15446	51	27	stability	stability	NOUN
cet-15446	51	28	of	of	ADP
cet-15446	51	29	nanovesicles	nanovesicle	NOUN
cet-15446	51	30	over	over	ADP
cet-15446	51	31	time	time	NOUN
cet-15446	51	32	.	.	PUNCT
cet-15446	52	1	the	the	DET
cet-15446	52	2	morphology	morphology	NOUN
cet-15446	52	3	of	of	ADP
cet-15446	52	4	transfersomes	transfersome	NOUN
cet-15446	52	5	was	be	AUX
cet-15446	52	6	observed	observe	VERB
cet-15446	52	7	by	by	ADP
cet-15446	52	8	a	a	DET
cet-15446	52	9	field	field	NOUN
cet-15446	52	10	emission	emission	NOUN
cet-15446	52	11	scanning	scan	VERB
cet-15446	52	12	electron	electron	NOUN
cet-15446	52	13	microscope	microscope	NOUN
cet-15446	52	14	(	(	PUNCT
cet-15446	52	15	fe	fe	X
cet-15446	52	16	-	-	ADJ
cet-15446	52	17	sem	sem	NOUN
cet-15446	52	18	,	,	PUNCT
cet-15446	52	19	carl	carl	PROPN
cet-15446	52	20	zeiss	zeiss	PROPN
cet-15446	52	21	,	,	PUNCT
cet-15446	52	22	mod	mod	PROPN
cet-15446	52	23	.	.	PUNCT
cet-15446	52	24	supra	supra	PROPN
cet-15446	52	25	35	35	NUM
cet-15446	52	26	)	)	PUNCT
cet-15446	52	27	.	.	PUNCT
cet-15446	53	1	to	to	PART
cet-15446	53	2	perform	perform	VERB
cet-15446	53	3	this	this	DET
cet-15446	53	4	analysis	analysis	NOUN
cet-15446	53	5	,	,	PUNCT
cet-15446	53	6	samples	sample	NOUN
cet-15446	53	7	were	be	AUX
cet-15446	53	8	coated	coat	VERB
cet-15446	53	9	with	with	ADP
cet-15446	53	10	gold	gold	NOUN
cet-15446	53	11	,	,	PUNCT
cet-15446	53	12	using	use	VERB
cet-15446	53	13	a	a	DET
cet-15446	53	14	sputter	sputter	NOUN
cet-15446	53	15	coater	coater	NOUN
cet-15446	53	16	(	(	PUNCT
cet-15446	53	17	mod	mod	PROPN
cet-15446	53	18	.	.	PROPN
cet-15446	53	19	108	108	NUM
cet-15446	53	20	a	a	PRON
cet-15446	53	21	,	,	PUNCT
cet-15446	53	22	agar	agar	VERB
cet-15446	53	23	auto	auto	NOUN
cet-15446	53	24	sputter	sputter	NOUN
cet-15446	53	25	coater	coater	NOUN
cet-15446	53	26	)	)	PUNCT
cet-15446	53	27	at	at	ADP
cet-15446	53	28	40	40	NUM
cet-15446	53	29	ma	ma	NOUN
cet-15446	53	30	for	for	ADP
cet-15446	53	31	180	180	NUM
cet-15446	53	32	s.	s.	PROPN
cet-15446	53	33	diclofenac	diclofenac	PROPN
cet-15446	53	34	sodium	sodium	NOUN
cet-15446	53	35	encapsulation	encapsulation	NOUN
cet-15446	53	36	efficiency	efficiency	NOUN
cet-15446	53	37	(	(	PUNCT
cet-15446	53	38	ee%	ee%	PROPN
cet-15446	53	39	)	)	PUNCT
cet-15446	53	40	was	be	AUX
cet-15446	53	41	determined	determine	VERB
cet-15446	53	42	by	by	ADP
cet-15446	53	43	using	use	VERB
cet-15446	53	44	an	an	DET
cet-15446	53	45	indirect	indirect	ADJ
cet-15446	53	46	method	method	NOUN
cet-15446	53	47	:	:	PUNCT
cet-15446	53	48	samples	sample	NOUN
cet-15446	53	49	were	be	AUX
cet-15446	53	50	centrifuged	centrifuge	VERB
cet-15446	53	51	(	(	PUNCT
cet-15446	53	52	centrifuge	centrifuge	NOUN
cet-15446	53	53	mod	mod	PROPN
cet-15446	53	54	.	.	PUNCT
cet-15446	54	1	iec	iec	PROPN
cet-15446	54	2	cl30r	cl30r	VERB
cet-15446	54	3	thermo	thermo	PROPN
cet-15446	54	4	scientific	scientific	PROPN
cet-15446	54	5	)	)	PUNCT
cet-15446	54	6	at	at	ADP
cet-15446	54	7	6500	6500	NUM
cet-15446	54	8	rpm	rpm	NOUN
cet-15446	54	9	for	for	ADP
cet-15446	54	10	30	30	NUM
cet-15446	54	11	min	min	NOUN
cet-15446	54	12	at	at	ADP
cet-15446	54	13	4	4	NUM
cet-15446	54	14	°	°	ADP
cet-15446	54	15	c	c	NOUN
cet-15446	54	16	using	use	VERB
cet-15446	54	17	amicon	amicon	ADJ
cet-15446	54	18	®	®	NOUN
cet-15446	54	19	ultra-15	ultra-15	PROPN
cet-15446	54	20	with	with	ADP
cet-15446	54	21	a	a	DET
cet-15446	54	22	cut	cut	NOUN
cet-15446	54	23	-	-	PUNCT
cet-15446	54	24	off	off	NOUN
cet-15446	54	25	of	of	ADP
cet-15446	54	26	30	30	NUM
cet-15446	54	27	kda	kda	NOUN
cet-15446	54	28	,	,	PUNCT
cet-15446	54	29	and	and	CCONJ
cet-15446	54	30	the	the	DET
cet-15446	54	31	absorbance	absorbance	NOUN
cet-15446	54	32	of	of	ADP
cet-15446	54	33	diclofenac	diclofenac	NOUN
cet-15446	54	34	into	into	ADP
cet-15446	54	35	the	the	DET
cet-15446	54	36	supernatant	supernatant	NOUN
cet-15446	54	37	was	be	AUX
cet-15446	54	38	read	read	VERB
cet-15446	54	39	at	at	ADP
cet-15446	54	40	λ=	λ=	ADJ
cet-15446	54	41	275	275	NUM
cet-15446	54	42	nm	nm	NOUN
cet-15446	54	43	by	by	ADP
cet-15446	54	44	using	use	VERB
cet-15446	54	45	an	an	DET
cet-15446	54	46	uv	uv	NOUN
cet-15446	54	47	-	-	PUNCT
cet-15446	54	48	vis	vis	X
cet-15446	54	49	spectrophotometer	spectrophotometer	X
cet-15446	54	50	(	(	PUNCT
cet-15446	54	51	mod	mod	PROPN
cet-15446	54	52	.	.	PROPN
cet-15446	54	53	cary	cary	PROPN
cet-15446	54	54	60	60	NUM
cet-15446	54	55	uv	uv	NOUN
cet-15446	54	56	-	-	PUNCT
cet-15446	54	57	vis	vis	X
cet-15446	54	58	,	,	PUNCT
cet-15446	54	59	agilent	agilent	PROPN
cet-15446	54	60	technologies	technology	NOUN
cet-15446	54	61	)	)	PUNCT
cet-15446	54	62	.	.	PUNCT
cet-15446	55	1	in	in	ADP
cet-15446	55	2	vitro	vitro	X
cet-15446	55	3	release	release	NOUN
cet-15446	55	4	tests	test	NOUN
cet-15446	55	5	were	be	AUX
cet-15446	55	6	performed	perform	VERB
cet-15446	55	7	by	by	ADP
cet-15446	55	8	introducing	introduce	VERB
cet-15446	55	9	5	5	NUM
cet-15446	55	10	ml	ml	NOUN
cet-15446	55	11	of	of	ADP
cet-15446	55	12	pellet	pellet	NOUN
cet-15446	55	13	into	into	ADP
cet-15446	55	14	a	a	DET
cet-15446	55	15	dialysis	dialysis	NOUN
cet-15446	55	16	bag	bag	NOUN
cet-15446	55	17	with	with	ADP
cet-15446	55	18	a	a	DET
cet-15446	55	19	cut	cut	NOUN
cet-15446	55	20	-	-	PUNCT
cet-15446	55	21	off	off	NOUN
cet-15446	55	22	of	of	ADP
cet-15446	55	23	14,000	14,000	NUM
cet-15446	55	24	da	da	X
cet-15446	55	25	(	(	PUNCT
cet-15446	55	26	merck	merck	PROPN
cet-15446	55	27	,	,	PUNCT
cet-15446	55	28	darmstadt	darmstadt	PROPN
cet-15446	55	29	,	,	PUNCT
cet-15446	55	30	germany	germany	PROPN
cet-15446	55	31	)	)	PUNCT
cet-15446	55	32	previously	previously	ADV
cet-15446	55	33	activated	activate	VERB
cet-15446	55	34	with	with	ADP
cet-15446	55	35	ethylenediaminetetraacetic	ethylenediaminetetraacetic	ADJ
cet-15446	55	36	acid	acid	NOUN
cet-15446	55	37	(	(	PUNCT
cet-15446	55	38	edta	edta	NOUN
cet-15446	55	39	)	)	PUNCT
cet-15446	55	40	.	.	PUNCT
cet-15446	56	1	the	the	DET
cet-15446	56	2	bag	bag	NOUN
cet-15446	56	3	was	be	AUX
cet-15446	56	4	,	,	PUNCT
cet-15446	56	5	then	then	ADV
cet-15446	56	6	,	,	PUNCT
cet-15446	56	7	immersed	immerse	VERB
cet-15446	56	8	in	in	ADP
cet-15446	56	9	80	80	NUM
cet-15446	56	10	ml	ml	NOUN
cet-15446	56	11	of	of	ADP
cet-15446	56	12	phosphate	phosphate	ADJ
cet-15446	56	13	buffer	buffer	NOUN
cet-15446	56	14	saline	saline	NOUN
cet-15446	56	15	(	(	PUNCT
cet-15446	56	16	ph	ph	NOUN
cet-15446	56	17	7.4	7.4	NUM
cet-15446	56	18	)	)	PUNCT
cet-15446	56	19	,	,	PUNCT
cet-15446	56	20	used	use	VERB
cet-15446	56	21	as	as	ADP
cet-15446	56	22	release	release	NOUN
cet-15446	56	23	medium	medium	NOUN
cet-15446	56	24	,	,	PUNCT
cet-15446	56	25	and	and	CCONJ
cet-15446	56	26	the	the	DET
cet-15446	56	27	temperature	temperature	NOUN
cet-15446	56	28	was	be	AUX
cet-15446	56	29	fixed	fix	VERB
cet-15446	56	30	at	at	ADP
cet-15446	56	31	37	37	NUM
cet-15446	56	32	°	°	NOUN
cet-15446	56	33	c	c	NOUN
cet-15446	56	34	.	.	PUNCT
cet-15446	57	1	the	the	DET
cet-15446	57	2	release	release	NOUN
cet-15446	57	3	of	of	ADP
cet-15446	57	4	diclofenac	diclofenac	NOUN
cet-15446	57	5	from	from	ADP
cet-15446	57	6	transfersomes	transfersome	NOUN
cet-15446	57	7	was	be	AUX
cet-15446	57	8	monitored	monitor	VERB
cet-15446	57	9	by	by	ADP
cet-15446	57	10	measuring	measure	VERB
cet-15446	57	11	its	its	PRON
cet-15446	57	12	absorbance	absorbance	NOUN
cet-15446	57	13	in	in	ADP
cet-15446	57	14	the	the	DET
cet-15446	57	15	liquid	liquid	ADJ
cet-15446	57	16	medium	medium	NOUN
cet-15446	57	17	over	over	ADP
cet-15446	57	18	time	time	NOUN
cet-15446	57	19	(	(	PUNCT
cet-15446	57	20	bucci	bucci	PROPN
cet-15446	57	21	et	et	PROPN
cet-15446	57	22	al	al	PROPN
cet-15446	57	23	.	.	PROPN
cet-15446	57	24	,	,	PUNCT
cet-15446	57	25	1998	1998	NUM
cet-15446	57	26	)	)	PUNCT
cet-15446	57	27	.	.	PUNCT
cet-15446	58	1	deformability	deformability	NOUN
cet-15446	58	2	tests	test	NOUN
cet-15446	58	3	were	be	AUX
cet-15446	58	4	also	also	ADV
cet-15446	58	5	performed	perform	VERB
cet-15446	58	6	using	use	VERB
cet-15446	58	7	a	a	DET
cet-15446	58	8	perfuser	perfuser	NOUN
cet-15446	58	9	(	(	PUNCT
cet-15446	58	10	mod	mod	PROPN
cet-15446	58	11	.	.	PUNCT
cet-15446	59	1	ne-300	ne-300	PROPN
cet-15446	59	2	,	,	PUNCT
cet-15446	59	3	just	just	ADV
cet-15446	59	4	infusion	infusion	NOUN
cet-15446	59	5	)	)	PUNCT
cet-15446	59	6	.	.	PUNCT
cet-15446	60	1	in	in	ADP
cet-15446	60	2	particular	particular	ADJ
cet-15446	60	3	,	,	PUNCT
cet-15446	60	4	the	the	DET
cet-15446	60	5	transfersomal	transfersomal	ADJ
cet-15446	60	6	suspension	suspension	NOUN
cet-15446	60	7	was	be	AUX
cet-15446	60	8	forced	force	VERB
cet-15446	60	9	through	through	ADP
cet-15446	60	10	a	a	DET
cet-15446	60	11	filter	filter	NOUN
cet-15446	60	12	with	with	ADP
cet-15446	60	13	a	a	DET
cet-15446	60	14	diameter	diameter	NOUN
cet-15446	60	15	of	of	ADP
cet-15446	60	16	100	100	NUM
cet-15446	60	17	nm	nm	NOUN
cet-15446	60	18	and	and	CCONJ
cet-15446	60	19	the	the	DET
cet-15446	60	20	deformability	deformability	NOUN
cet-15446	60	21	parameter	parameter	NOUN
cet-15446	60	22	(	(	PUNCT
cet-15446	60	23	pdef	pdef	NOUN
cet-15446	60	24	)	)	PUNCT
cet-15446	60	25	was	be	AUX
cet-15446	60	26	measured	measure	VERB
cet-15446	60	27	using	use	VERB
cet-15446	60	28	eq	eq	NOUN
cet-15446	61	1	(	(	PUNCT
cet-15446	61	2	1	1	NUM
cet-15446	61	3	)	)	PUNCT
cet-15446	61	4	,	,	PUNCT
cet-15446	61	5	where	where	SCONJ
cet-15446	61	6	:	:	PUNCT
cet-15446	61	7	din	din	NOUN
cet-15446	61	8	is	be	AUX
cet-15446	61	9	the	the	DET
cet-15446	61	10	mhd	mhd	NOUN
cet-15446	61	11	of	of	ADP
cet-15446	61	12	transfersomes	transfersome	NOUN
cet-15446	61	13	before	before	ADP
cet-15446	61	14	the	the	DET
cet-15446	61	15	deformation	deformation	NOUN
cet-15446	61	16	;	;	PUNCT
cet-15446	61	17	df	df	PROPN
cet-15446	61	18	is	be	AUX
cet-15446	61	19	the	the	DET
cet-15446	61	20	mhd	mhd	NOUN
cet-15446	61	21	of	of	ADP
cet-15446	61	22	transfersomes	transfersome	NOUN
cet-15446	61	23	after	after	ADP
cet-15446	61	24	the	the	DET
cet-15446	61	25	deformation	deformation	NOUN
cet-15446	61	26	.	.	PUNCT
cet-15446	62	1	pdef	pdef	NOUN
cet-15446	62	2	=	=	SYM
cet-15446	62	3	{	{	PUNCT
cet-15446	62	4	1	1	NUM
cet-15446	62	5	–	–	PUNCT
cet-15446	62	6	[	[	X
cet-15446	62	7	(	(	PUNCT
cet-15446	62	8	din	din	VERB
cet-15446	62	9	–	–	PUNCT
cet-15446	62	10	df)/din	df)/din	NOUN
cet-15446	62	11	)	)	PUNCT
cet-15446	62	12	]	]	PUNCT
cet-15446	62	13	}	}	PUNCT
cet-15446	62	14	x	x	SYM
cet-15446	62	15	100	100	NUM
cet-15446	62	16	(	(	PUNCT
cet-15446	62	17	1	1	NUM
cet-15446	62	18	)	)	PUNCT
cet-15446	62	19	3	3	NUM
cet-15446	62	20	.	.	NOUN
cet-15446	62	21	results	result	NOUN
cet-15446	62	22	and	and	CCONJ
cet-15446	62	23	discussion	discussion	NOUN
cet-15446	62	24	all	all	DET
cet-15446	62	25	the	the	DET
cet-15446	62	26	experiments	experiment	NOUN
cet-15446	62	27	were	be	AUX
cet-15446	62	28	carried	carry	VERB
cet-15446	62	29	out	out	ADP
cet-15446	62	30	using	use	VERB
cet-15446	62	31	the	the	DET
cet-15446	62	32	same	same	ADJ
cet-15446	62	33	parameters	parameter	NOUN
cet-15446	62	34	optimized	optimize	VERB
cet-15446	62	35	in	in	ADP
cet-15446	62	36	previous	previous	ADJ
cet-15446	62	37	works	work	NOUN
cet-15446	62	38	(	(	PUNCT
cet-15446	62	39	baldino	baldino	PROPN
cet-15446	62	40	and	and	CCONJ
cet-15446	62	41	reverchon	reverchon	PROPN
cet-15446	62	42	,	,	PUNCT
cet-15446	62	43	2023	2023	NUM
cet-15446	62	44	):	):	PUNCT
cet-15446	62	45	i.e.	i.e.	X
cet-15446	62	46	,	,	PUNCT
cet-15446	62	47	pressure	pressure	NOUN
cet-15446	62	48	100	100	NUM
cet-15446	62	49	bar	bar	NOUN
cet-15446	62	50	,	,	PUNCT
cet-15446	62	51	temperature	temperature	NOUN
cet-15446	62	52	40	40	NUM
cet-15446	62	53	°	°	SYM
cet-15446	62	54	c	c	NOUN
cet-15446	62	55	,	,	PUNCT
cet-15446	62	56	aqueous	aqueous	ADJ
cet-15446	62	57	solution	solution	NOUN
cet-15446	62	58	flow	flow	NOUN
cet-15446	62	59	rate	rate	NOUN
cet-15446	62	60	7	7	NUM
cet-15446	62	61	ml	ml	NOUN
cet-15446	62	62	/	/	SYM
cet-15446	62	63	min	min	NOUN
cet-15446	62	64	,	,	PUNCT
cet-15446	62	65	ethanolic	ethanolic	ADJ
cet-15446	62	66	solution	solution	NOUN
cet-15446	62	67	flow	flow	NOUN
cet-15446	62	68	rate	rate	NOUN
cet-15446	62	69	3.5	3.5	NUM
cet-15446	62	70	ml	ml	NOUN
cet-15446	62	71	/	/	SYM
cet-15446	62	72	min	min	NOUN
cet-15446	62	73	,	,	PUNCT
cet-15446	62	74	and	and	CCONJ
cet-15446	62	75	co2	co2	NOUN
cet-15446	62	76	flow	flow	NOUN
cet-15446	62	77	rate	rate	NOUN
cet-15446	62	78	6.5	6.5	NUM
cet-15446	62	79	g	g	NOUN
cet-15446	62	80	/	/	SYM
cet-15446	62	81	min	min	NOUN
cet-15446	62	82	.	.	PROPN
cet-15446	62	83	3.1	3.1	NUM
cet-15446	62	84	production	production	NOUN
cet-15446	62	85	of	of	ADP
cet-15446	62	86	empty	empty	ADJ
cet-15446	62	87	transfersomes	transfersome	NOUN
cet-15446	62	88	the	the	DET
cet-15446	62	89	first	first	ADJ
cet-15446	62	90	set	set	NOUN
cet-15446	62	91	of	of	ADP
cet-15446	62	92	experiments	experiment	NOUN
cet-15446	62	93	was	be	AUX
cet-15446	62	94	performed	perform	VERB
cet-15446	62	95	to	to	PART
cet-15446	62	96	study	study	VERB
cet-15446	62	97	the	the	DET
cet-15446	62	98	influence	influence	NOUN
cet-15446	62	99	of	of	ADP
cet-15446	62	100	different	different	ADJ
cet-15446	62	101	amounts	amount	NOUN
cet-15446	62	102	of	of	ADP
cet-15446	62	103	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	62	104	(	(	PUNCT
cet-15446	62	105	i.e.	i.e.	X
cet-15446	62	106	,	,	PUNCT
cet-15446	62	107	500	500	NUM
cet-15446	62	108	,	,	PUNCT
cet-15446	62	109	1000	1000	NUM
cet-15446	62	110	,	,	PUNCT
cet-15446	62	111	and	and	CCONJ
cet-15446	62	112	2000	2000	NUM
cet-15446	62	113	mg	mg	NUM
cet-15446	62	114	)	)	PUNCT
cet-15446	62	115	on	on	ADP
cet-15446	62	116	the	the	DET
cet-15446	62	117	vesicle	vesicle	NOUN
cet-15446	62	118	size	size	NOUN
cet-15446	62	119	,	,	PUNCT
cet-15446	62	120	zeta	zeta	NOUN
cet-15446	62	121	-	-	PUNCT
cet-15446	62	122	potential	potential	ADJ
cet-15446	62	123	and	and	CCONJ
cet-15446	62	124	stability	stability	NOUN
cet-15446	62	125	of	of	ADP
cet-15446	62	126	empty	empty	ADJ
cet-15446	62	127	transfersomes	transfersome	NOUN
cet-15446	62	128	.	.	PUNCT
cet-15446	63	1	for	for	ADP
cet-15446	63	2	all	all	DET
cet-15446	63	3	the	the	DET
cet-15446	63	4	experiments	experiment	NOUN
cet-15446	63	5	,	,	PUNCT
cet-15446	63	6	the	the	DET
cet-15446	63	7	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	63	8	to	to	PART
cet-15446	63	9	span	span	VERB
cet-15446	63	10	80	80	NUM
cet-15446	63	11	weight	weight	NOUN
cet-15446	63	12	ratio	ratio	NOUN
cet-15446	63	13	was	be	AUX
cet-15446	63	14	set	set	VERB
cet-15446	63	15	at	at	ADP
cet-15446	63	16	80:20	80:20	NUM
cet-15446	63	17	.	.	PUNCT
cet-15446	64	1	the	the	DET
cet-15446	64	2	results	result	NOUN
cet-15446	64	3	obtained	obtain	VERB
cet-15446	64	4	by	by	ADP
cet-15446	64	5	dls	dls	PROPN
cet-15446	64	6	analysis	analysis	NOUN
cet-15446	64	7	and	and	CCONJ
cet-15446	64	8	expressed	express	VERB
cet-15446	64	9	in	in	ADP
cet-15446	64	10	terms	term	NOUN
cet-15446	64	11	of	of	ADP
cet-15446	64	12	mhd	mhd	NOUN
cet-15446	64	13	,	,	PUNCT
cet-15446	64	14	pdi	pdi	NOUN
cet-15446	64	15	and	and	CCONJ
cet-15446	64	16	zeta	zeta	NOUN
cet-15446	64	17	-	-	PUNCT
cet-15446	64	18	potential	potential	NOUN
cet-15446	64	19	,	,	PUNCT
cet-15446	64	20	are	be	AUX
cet-15446	64	21	summarized	summarize	VERB
cet-15446	64	22	in	in	ADP
cet-15446	64	23	table	table	NOUN
cet-15446	64	24	1	1	NUM
cet-15446	64	25	.	.	PUNCT
cet-15446	64	26	table	table	NOUN
cet-15446	64	27	1	1	NUM
cet-15446	64	28	:	:	PUNCT
cet-15446	64	29	dls	dls	PROPN
cet-15446	64	30	results	result	VERB
cet-15446	64	31	related	relate	VERB
cet-15446	64	32	to	to	ADP
cet-15446	64	33	empty	empty	ADJ
cet-15446	64	34	transfersomes	transfersome	NOUN
cet-15446	64	35	produced	produce	VERB
cet-15446	64	36	at	at	ADP
cet-15446	64	37	different	different	ADJ
cet-15446	64	38	amount	amount	NOUN
cet-15446	64	39	of	of	ADP
cet-15446	64	40	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	64	41	sample	sample	NOUN
cet-15446	64	42	pc	pc	NOUN
cet-15446	64	43	,	,	PUNCT
cet-15446	64	44	mg	mg	PROPN
cet-15446	64	45	mhd	mhd	PROPN
cet-15446	64	46	,	,	PUNCT
cet-15446	64	47	nm	nm	ADV
cet-15446	64	48	pdi	pdi	ADJ
cet-15446	64	49	ζ	ζ	NOUN
cet-15446	64	50	-	-	PUNCT
cet-15446	64	51	potential	potential	NOUN
cet-15446	64	52	,	,	PUNCT
cet-15446	64	53	mv	mv	PROPN
cet-15446	64	54	t1	t1	PROPN
cet-15446	64	55	500	500	NUM
cet-15446	64	56	154	154	NUM
cet-15446	64	57	±	±	NUM
cet-15446	64	58	61	61	NUM
cet-15446	64	59	bimodal	bimodal	NOUN
cet-15446	64	60	-13.00	-13.00	PROPN
cet-15446	64	61	±	±	PROPN
cet-15446	64	62	4.11	4.11	NUM
cet-15446	64	63	t2	t2	NOUN
cet-15446	64	64	1000	1000	NUM
cet-15446	64	65	183	183	NUM
cet-15446	64	66	±	±	NUM
cet-15446	64	67	100	100	NUM
cet-15446	64	68	0.304	0.304	NUM
cet-15446	64	69	-21.00	-21.00	SYM
cet-15446	64	70	±	±	NUM
cet-15446	64	71	6.03	6.03	NUM
cet-15446	64	72	t3	t3	NOUN
cet-15446	64	73	2000	2000	NUM
cet-15446	64	74	172	172	NUM
cet-15446	64	75	±	±	NUM
cet-15446	64	76	112	112	NUM
cet-15446	64	77	0.424	0.424	NUM
cet-15446	64	78	-9.80	-9.80	NUM
cet-15446	64	79	±	±	NUM
cet-15446	64	80	7.51	7.51	NUM
cet-15446	64	81	figure	figure	NOUN
cet-15446	64	82	1b	1b	NUM
cet-15446	64	83	shows	show	VERB
cet-15446	64	84	that	that	SCONJ
cet-15446	64	85	the	the	DET
cet-15446	64	86	formulation	formulation	NOUN
cet-15446	64	87	prepared	prepare	VERB
cet-15446	64	88	using	use	VERB
cet-15446	64	89	an	an	DET
cet-15446	64	90	amount	amount	NOUN
cet-15446	64	91	of	of	ADP
cet-15446	64	92	phosphatidylcholine	phosphatidylcholine	NOUN
cet-15446	64	93	equal	equal	ADJ
cet-15446	64	94	to	to	ADP
cet-15446	64	95	1000	1000	NUM
cet-15446	64	96	mg	mg	NOUN
cet-15446	64	97	allowed	allow	VERB
cet-15446	64	98	the	the	DET
cet-15446	64	99	formation	formation	NOUN
cet-15446	64	100	of	of	ADP
cet-15446	64	101	transfersomes	transfersome	NOUN
cet-15446	64	102	with	with	ADP
cet-15446	64	103	nanometric	nanometric	ADJ
cet-15446	64	104	size	size	NOUN
cet-15446	64	105	and	and	CCONJ
cet-15446	64	106	unimodal	unimodal	ADJ
cet-15446	64	107	size	size	NOUN
cet-15446	64	108	distribution	distribution	NOUN
cet-15446	64	109	.	.	PUNCT
cet-15446	65	1	transfersomes	transfersome	NOUN
cet-15446	65	2	produced	produce	VERB
cet-15446	65	3	with	with	ADP
cet-15446	65	4	a	a	DET
cet-15446	65	5	pc	pc	NOUN
cet-15446	65	6	concentration	concentration	NOUN
cet-15446	65	7	of	of	ADP
cet-15446	65	8	5	5	NUM
cet-15446	65	9	mg	mg	NOUN
cet-15446	65	10	/	/	SYM
cet-15446	65	11	ml	ml	NOUN
cet-15446	65	12	were	be	AUX
cet-15446	65	13	characterized	characterize	VERB
cet-15446	65	14	by	by	ADP
cet-15446	65	15	a	a	DET
cet-15446	65	16	slightly	slightly	ADV
cet-15446	65	17	bimodal	bimodal	ADJ
cet-15446	65	18	size	size	NOUN
cet-15446	65	19	distribution	distribution	NOUN
cet-15446	65	20	(	(	PUNCT
cet-15446	65	21	figure	figure	NOUN
cet-15446	65	22	1a	1a	NOUN
cet-15446	65	23	)	)	PUNCT
cet-15446	65	24	,	,	PUNCT
cet-15446	65	25	probably	probably	ADV
cet-15446	65	26	due	due	ADP
cet-15446	65	27	to	to	ADP
cet-15446	65	28	an	an	DET
cet-15446	65	29	insufficient	insufficient	ADJ
cet-15446	65	30	amount	amount	NOUN
cet-15446	65	31	of	of	ADP
cet-15446	65	32	pc	pc	NOUN
cet-15446	65	33	to	to	PART
cet-15446	65	34	form	form	VERB
cet-15446	65	35	the	the	DET
cet-15446	65	36	double	double	ADJ
cet-15446	65	37	layer	layer	NOUN
cet-15446	65	38	,	,	PUNCT
cet-15446	65	39	resulting	result	VERB
cet-15446	65	40	in	in	ADP
cet-15446	65	41	the	the	DET
cet-15446	65	42	formation	formation	NOUN
cet-15446	65	43	of	of	ADP
cet-15446	65	44	selfassembled	selfassembled	ADJ
cet-15446	65	45	micelles	micelle	NOUN
cet-15446	65	46	of	of	ADP
cet-15446	65	47	about	about	ADV
cet-15446	65	48	42	42	NUM
cet-15446	65	49	nm	nm	NOUN
cet-15446	65	50	.	.	PUNCT
cet-15446	66	1	transfersomes	transfersome	NOUN
cet-15446	66	2	with	with	ADP
cet-15446	66	3	nanometric	nanometric	ADJ
cet-15446	66	4	size	size	NOUN
cet-15446	66	5	and	and	CCONJ
cet-15446	66	6	unimodal	unimodal	ADJ
cet-15446	66	7	size	size	NOUN
cet-15446	66	8	distributions	distribution	NOUN
cet-15446	66	9	were	be	AUX
cet-15446	66	10	also	also	ADV
cet-15446	66	11	obtained	obtain	VERB
cet-15446	66	12	using	use	VERB
cet-15446	66	13	an	an	DET
cet-15446	66	14	amount	amount	NOUN
cet-15446	66	15	of	of	ADP
cet-15446	66	16	pc	pc	NOUN
cet-15446	66	17	equal	equal	ADJ
cet-15446	66	18	to	to	ADP
cet-15446	66	19	2000	2000	NUM
cet-15446	66	20	mg	mg	PROPN
cet-15446	67	1	(	(	PUNCT
cet-15446	67	2	figure	figure	NOUN
cet-15446	67	3	1c	1c	NOUN
cet-15446	67	4	)	)	PUNCT
cet-15446	67	5	;	;	PUNCT
cet-15446	67	6	but	but	CCONJ
cet-15446	67	7	they	they	PRON
cet-15446	67	8	showed	show	VERB
cet-15446	67	9	a	a	DET
cet-15446	67	10	large	large	ADJ
cet-15446	67	11	polydispersity	polydispersity	NOUN
cet-15446	67	12	index	index	NOUN
cet-15446	67	13	(	(	PUNCT
cet-15446	67	14	0.424	0.424	NUM
cet-15446	67	15	)	)	PUNCT
cet-15446	67	16	.	.	PUNCT
cet-15446	68	1	in	in	ADP
cet-15446	68	2	addition	addition	NOUN
cet-15446	68	3	,	,	PUNCT
cet-15446	68	4	the	the	DET
cet-15446	68	5	absolute	absolute	ADJ
cet-15446	68	6	value	value	NOUN
cet-15446	68	7	of	of	ADP
cet-15446	68	8	t3	t3	PROPN
cet-15446	68	9	zeta	zeta	PROPN
cet-15446	68	10	-	-	PUNCT
cet-15446	68	11	potential	potential	NOUN
cet-15446	68	12	was	be	AUX
cet-15446	68	13	the	the	DET
cet-15446	68	14	lowest	low	ADJ
cet-15446	68	15	one	one	NUM
cet-15446	68	16	(	(	PUNCT
cet-15446	68	17	-9.80	-9.80	NUM
cet-15446	68	18	±	±	NUM
cet-15446	68	19	7.51	7.51	NUM
cet-15446	68	20	mv	mv	NOUN
cet-15446	68	21	)	)	PUNCT
cet-15446	68	22	compared	compare	VERB
cet-15446	68	23	with	with	ADP
cet-15446	68	24	the	the	DET
cet-15446	68	25	values	value	NOUN
cet-15446	68	26	obtained	obtain	VERB
cet-15446	68	27	for	for	ADP
cet-15446	68	28	the	the	DET
cet-15446	68	29	other	other	ADJ
cet-15446	68	30	formulations	formulation	NOUN
cet-15446	68	31	(	(	PUNCT
cet-15446	68	32	i.e.	i.e.	X
cet-15446	68	33	,	,	PUNCT
cet-15446	68	34	t1	t1	NOUN
cet-15446	68	35	and	and	CCONJ
cet-15446	68	36	t2	t2	NOUN
cet-15446	68	37	)	)	PUNCT
cet-15446	68	38	and	and	CCONJ
cet-15446	68	39	this	this	DET
cet-15446	68	40	result	result	NOUN
cet-15446	68	41	suggested	suggest	VERB
cet-15446	68	42	less	less	ADV
cet-15446	68	43	stable	stable	ADJ
cet-15446	68	44	nanovesicles	nanovesicle	NOUN
cet-15446	68	45	over	over	ADP
cet-15446	68	46	time	time	NOUN
cet-15446	68	47	.	.	PUNCT
cet-15446	69	1	therefore	therefore	ADV
cet-15446	69	2	,	,	PUNCT
cet-15446	69	3	t2	t2	PROPN
cet-15446	69	4	was	be	AUX
cet-15446	69	5	selected	select	VERB
cet-15446	69	6	as	as	ADP
cet-15446	69	7	the	the	DET
cet-15446	69	8	best	good	ADJ
cet-15446	69	9	formulation	formulation	NOUN
cet-15446	69	10	of	of	ADP
cet-15446	69	11	empty	empty	ADJ
cet-15446	69	12	transfersomes	transfersome	NOUN
cet-15446	69	13	with	with	ADP
cet-15446	69	14	a	a	DET
cet-15446	69	15	longer	long	ADJ
cet-15446	69	16	stability	stability	NOUN
cet-15446	69	17	over	over	ADP
cet-15446	69	18	time	time	NOUN
cet-15446	69	19	,	,	PUNCT
cet-15446	69	20	as	as	SCONJ
cet-15446	69	21	confirmed	confirm	VERB
cet-15446	69	22	by	by	ADP
cet-15446	69	23	the	the	DET
cet-15446	69	24	higher	high	ADJ
cet-15446	69	25	absolute	absolute	ADJ
cet-15446	69	26	value	value	NOUN
cet-15446	69	27	of	of	ADP
cet-15446	69	28	zeta	zeta	NOUN
cet-15446	69	29	-	-	PUNCT
cet-15446	69	30	potential	potential	NOUN
cet-15446	69	31	(	(	PUNCT
cet-15446	69	32	-21.00	-21.00	PROPN
cet-15446	69	33	±	±	NUM
cet-15446	69	34	6.03	6.03	NUM
cet-15446	69	35	mv	mv	NOUN
cet-15446	69	36	)	)	PUNCT
cet-15446	69	37	.	.	PUNCT
cet-15446	70	1	1173	1173	NUM
cet-15446	70	2	(	(	PUNCT
cet-15446	70	3	a	a	NOUN
cet-15446	70	4	)	)	PUNCT
cet-15446	70	5	(	(	PUNCT
cet-15446	70	6	b	b	X
cet-15446	70	7	)	)	PUNCT
cet-15446	70	8	(	(	PUNCT
cet-15446	70	9	c	c	X
cet-15446	70	10	)	)	PUNCT
cet-15446	70	11	figure	figure	NOUN
cet-15446	70	12	1	1	NUM
cet-15446	70	13	:	:	PUNCT
cet-15446	70	14	particle	particle	NOUN
cet-15446	70	15	size	size	NOUN
cet-15446	70	16	distribution	distribution	NOUN
cet-15446	70	17	of	of	ADP
cet-15446	70	18	empty	empty	ADJ
cet-15446	70	19	transfersomes	transfersome	NOUN
cet-15446	70	20	produced	produce	VERB
cet-15446	70	21	at	at	ADP
cet-15446	70	22	different	different	ADJ
cet-15446	70	23	pc	pc	NOUN
cet-15446	70	24	concentration	concentration	NOUN
cet-15446	70	25	values	value	NOUN
cet-15446	70	26	:	:	PUNCT
cet-15446	70	27	(	(	PUNCT
cet-15446	70	28	a	a	X
cet-15446	70	29	)	)	PUNCT
cet-15446	70	30	5	5	NUM
cet-15446	70	31	mg	mg	NUM
cet-15446	70	32	/	/	SYM
cet-15446	70	33	ml	ml	NOUN
cet-15446	70	34	,	,	PUNCT
cet-15446	70	35	(	(	PUNCT
cet-15446	70	36	b	b	NOUN
cet-15446	70	37	)	)	PUNCT
cet-15446	70	38	10	10	NUM
cet-15446	70	39	mg	mg	NUM
cet-15446	70	40	/	/	SYM
cet-15446	70	41	ml	ml	NOUN
cet-15446	70	42	,	,	PUNCT
cet-15446	70	43	(	(	PUNCT
cet-15446	70	44	c	c	NOUN
cet-15446	70	45	)	)	PUNCT
cet-15446	70	46	20	20	NUM
cet-15446	70	47	mg	mg	NUM
cet-15446	70	48	/	/	SYM
cet-15446	70	49	ml	ml	PROPN
cet-15446	70	50	3.2	3.2	NUM
cet-15446	70	51	production	production	NOUN
cet-15446	70	52	of	of	ADP
cet-15446	70	53	diclofenac	diclofenac	NOUN
cet-15446	70	54	-	-	PUNCT
cet-15446	70	55	loaded	load	VERB
cet-15446	70	56	transfersomes	transfersome	NOUN
cet-15446	70	57	the	the	DET
cet-15446	70	58	best	good	ADJ
cet-15446	70	59	formulation	formulation	NOUN
cet-15446	70	60	obtained	obtain	VERB
cet-15446	70	61	using	use	VERB
cet-15446	70	62	1000	1000	NUM
cet-15446	70	63	mg	mg	NOUN
cet-15446	70	64	of	of	ADP
cet-15446	70	65	pc	pc	NOUN
cet-15446	70	66	was	be	AUX
cet-15446	70	67	,	,	PUNCT
cet-15446	70	68	then	then	ADV
cet-15446	70	69	,	,	PUNCT
cet-15446	70	70	tested	test	VERB
cet-15446	70	71	to	to	PART
cet-15446	70	72	encapsulate	encapsulate	VERB
cet-15446	70	73	diclofenac	diclofenac	NOUN
cet-15446	70	74	with	with	ADP
cet-15446	70	75	a	a	DET
cet-15446	70	76	drug	drug	NOUN
cet-15446	70	77	-	-	PUNCT
cet-15446	70	78	tolipid	tolipid	ADJ
cet-15446	70	79	ratio	ratio	NOUN
cet-15446	70	80	(	(	PUNCT
cet-15446	70	81	dlr	dlr	NOUN
cet-15446	70	82	)	)	PUNCT
cet-15446	70	83	of	of	ADP
cet-15446	70	84	1	1	NUM
cet-15446	70	85	%	%	NOUN
cet-15446	70	86	on	on	ADP
cet-15446	70	87	a	a	DET
cet-15446	70	88	mass	mass	ADJ
cet-15446	70	89	basis	basis	NOUN
cet-15446	70	90	.	.	PUNCT
cet-15446	71	1	diclofenac	diclofenac	NOUN
cet-15446	71	2	-	-	PUNCT
cet-15446	71	3	loaded	load	VERB
cet-15446	71	4	transfersomes	transfersome	NOUN
cet-15446	71	5	were	be	AUX
cet-15446	71	6	characterized	characterize	VERB
cet-15446	71	7	by	by	ADP
cet-15446	71	8	a	a	DET
cet-15446	71	9	unimodal	unimodal	ADJ
cet-15446	71	10	size	size	NOUN
cet-15446	71	11	distribution	distribution	NOUN
cet-15446	71	12	(	(	PUNCT
cet-15446	71	13	figure	figure	NOUN
cet-15446	71	14	2	2	NUM
cet-15446	71	15	)	)	PUNCT
cet-15446	71	16	with	with	ADP
cet-15446	71	17	a	a	DET
cet-15446	71	18	mean	mean	ADJ
cet-15446	71	19	diameter	diameter	NOUN
cet-15446	71	20	of	of	ADP
cet-15446	71	21	208	208	NUM
cet-15446	71	22	±	±	NUM
cet-15446	71	23	98	98	NUM
cet-15446	71	24	nm	nm	NOUN
cet-15446	71	25	,	,	PUNCT
cet-15446	71	26	a	a	DET
cet-15446	71	27	pdi	pdi	NOUN
cet-15446	71	28	equal	equal	ADJ
cet-15446	71	29	to	to	ADP
cet-15446	71	30	0.191	0.191	NUM
cet-15446	71	31	and	and	CCONJ
cet-15446	71	32	a	a	DET
cet-15446	71	33	zeta	zeta	NOUN
cet-15446	71	34	-	-	NOUN
cet-15446	71	35	potential	potential	NOUN
cet-15446	71	36	of	of	ADP
cet-15446	71	37	15.40	15.40	NUM
cet-15446	71	38	±	±	NUM
cet-15446	71	39	3.60	3.60	NUM
cet-15446	71	40	mv	mv	NOUN
cet-15446	71	41	.	.	PUNCT
cet-15446	72	1	the	the	DET
cet-15446	72	2	mean	mean	ADJ
cet-15446	72	3	hydrodynamic	hydrodynamic	ADJ
cet-15446	72	4	diameter	diameter	NOUN
cet-15446	72	5	of	of	ADP
cet-15446	72	6	loaded	load	VERB
cet-15446	72	7	transferosomes	transferosome	NOUN
cet-15446	72	8	was	be	AUX
cet-15446	72	9	slightly	slightly	ADV
cet-15446	72	10	larger	large	ADJ
cet-15446	72	11	than	than	ADP
cet-15446	72	12	the	the	DET
cet-15446	72	13	one	one	NOUN
cet-15446	72	14	obtained	obtain	VERB
cet-15446	72	15	for	for	ADP
cet-15446	72	16	empty	empty	ADJ
cet-15446	72	17	transfersomes	transfersome	NOUN
cet-15446	72	18	,	,	PUNCT
cet-15446	72	19	because	because	SCONJ
cet-15446	72	20	of	of	ADP
cet-15446	72	21	the	the	DET
cet-15446	72	22	presence	presence	NOUN
cet-15446	72	23	of	of	ADP
cet-15446	72	24	the	the	DET
cet-15446	72	25	drug	drug	NOUN
cet-15446	72	26	in	in	ADP
cet-15446	72	27	the	the	DET
cet-15446	72	28	internal	internal	ADJ
cet-15446	72	29	core	core	NOUN
cet-15446	72	30	of	of	ADP
cet-15446	72	31	nanovesicles	nanovesicle	NOUN
cet-15446	72	32	.	.	PUNCT
cet-15446	73	1	diclofenac	diclofenac	ADJ
cet-15446	73	2	encapsulation	encapsulation	NOUN
cet-15446	73	3	efficiency	efficiency	NOUN
cet-15446	73	4	was	be	AUX
cet-15446	73	5	measured	measure	VERB
cet-15446	73	6	as	as	SCONJ
cet-15446	73	7	reported	report	VERB
cet-15446	73	8	in	in	ADP
cet-15446	73	9	section	section	NOUN
cet-15446	73	10	2.4	2.4	NUM
cet-15446	73	11	,	,	PUNCT
cet-15446	73	12	yielding	yield	VERB
cet-15446	73	13	a	a	DET
cet-15446	73	14	value	value	NOUN
cet-15446	73	15	of	of	ADP
cet-15446	73	16	74	74	NUM
cet-15446	73	17	%	%	NOUN
cet-15446	73	18	;	;	PUNCT
cet-15446	73	19	whereas	whereas	SCONJ
cet-15446	73	20	the	the	DET
cet-15446	73	21	deformability	deformability	NOUN
cet-15446	73	22	parameter	parameter	NOUN
cet-15446	73	23	was	be	AUX
cet-15446	73	24	equal	equal	ADJ
cet-15446	73	25	to	to	ADP
cet-15446	73	26	74	74	NUM
cet-15446	73	27	%	%	NOUN
cet-15446	73	28	,	,	PUNCT
cet-15446	73	29	confirming	confirm	VERB
cet-15446	73	30	the	the	DET
cet-15446	73	31	deformation	deformation	NOUN
cet-15446	73	32	properties	property	NOUN
cet-15446	73	33	of	of	ADP
cet-15446	73	34	loaded	loaded	ADJ
cet-15446	73	35	transferosomes	transferosome	NOUN
cet-15446	73	36	.	.	PUNCT
cet-15446	74	1	figure	figure	VERB
cet-15446	74	2	2	2	NUM
cet-15446	74	3	:	:	PUNCT
cet-15446	74	4	particle	particle	NOUN
cet-15446	74	5	size	size	NOUN
cet-15446	74	6	distribution	distribution	NOUN
cet-15446	74	7	of	of	ADP
cet-15446	74	8	diclofenac	diclofenac	NOUN
cet-15446	74	9	-	-	PUNCT
cet-15446	74	10	loaded	load	VERB
cet-15446	74	11	transfersomes	transfersome	NOUN
cet-15446	74	12	produced	produce	VERB
cet-15446	74	13	by	by	ADP
cet-15446	74	14	supersomes	supersome	NOUN
cet-15446	74	15	at	at	ADP
cet-15446	74	16	a	a	DET
cet-15446	74	17	drug	drug	NOUN
cet-15446	74	18	-	-	PUNCT
cet-15446	74	19	tolipid	tolipid	ADJ
cet-15446	74	20	ratio	ratio	NOUN
cet-15446	74	21	of	of	ADP
cet-15446	74	22	1	1	NUM
cet-15446	74	23	%	%	NOUN
cet-15446	74	24	(	(	PUNCT
cet-15446	74	25	w	w	NOUN
cet-15446	74	26	/	/	SYM
cet-15446	74	27	w	w	NOUN
cet-15446	74	28	)	)	PUNCT
cet-15446	74	29	the	the	DET
cet-15446	74	30	morphology	morphology	NOUN
cet-15446	74	31	of	of	ADP
cet-15446	74	32	transfersomes	transfersome	NOUN
cet-15446	74	33	was	be	AUX
cet-15446	74	34	observed	observe	VERB
cet-15446	74	35	by	by	ADP
cet-15446	74	36	fe	fe	X
cet-15446	74	37	-	-	NOUN
cet-15446	74	38	sem	sem	NOUN
cet-15446	74	39	for	for	ADP
cet-15446	74	40	empty	empty	ADJ
cet-15446	74	41	and	and	CCONJ
cet-15446	74	42	drug	drug	NOUN
cet-15446	74	43	-	-	PUNCT
cet-15446	74	44	loaded	load	VERB
cet-15446	74	45	nanovesicles	nanovesicle	NOUN
cet-15446	74	46	.	.	PUNCT
cet-15446	75	1	in	in	ADP
cet-15446	75	2	both	both	DET
cet-15446	75	3	cases	case	NOUN
cet-15446	75	4	,	,	PUNCT
cet-15446	75	5	spherical	spherical	ADJ
cet-15446	75	6	vesicles	vesicle	NOUN
cet-15446	75	7	were	be	AUX
cet-15446	75	8	produced	produce	VERB
cet-15446	75	9	(	(	PUNCT
cet-15446	75	10	figure	figure	NOUN
cet-15446	75	11	3a	3a	NUM
cet-15446	75	12	-	-	SYM
cet-15446	75	13	b	b	NOUN
cet-15446	75	14	)	)	PUNCT
cet-15446	75	15	,	,	PUNCT
cet-15446	75	16	indicating	indicate	VERB
cet-15446	75	17	that	that	SCONJ
cet-15446	75	18	the	the	DET
cet-15446	75	19	encapsulation	encapsulation	NOUN
cet-15446	75	20	process	process	NOUN
cet-15446	75	21	did	do	AUX
cet-15446	75	22	not	not	PART
cet-15446	75	23	significantly	significantly	ADV
cet-15446	75	24	modify	modify	VERB
cet-15446	75	25	their	their	PRON
cet-15446	75	26	morphology	morphology	NOUN
cet-15446	75	27	.	.	PUNCT
cet-15446	76	1	moreover	moreover	ADV
cet-15446	76	2	,	,	PUNCT
cet-15446	76	3	vesicles	vesicle	NOUN
cet-15446	76	4	showed	show	VERB
cet-15446	76	5	a	a	DET
cet-15446	76	6	nanometric	nanometric	ADJ
cet-15446	76	7	size	size	NOUN
cet-15446	76	8	,	,	PUNCT
cet-15446	76	9	in	in	ADP
cet-15446	76	10	agreement	agreement	NOUN
cet-15446	76	11	with	with	ADP
cet-15446	76	12	the	the	DET
cet-15446	76	13	results	result	NOUN
cet-15446	76	14	obtained	obtain	VERB
cet-15446	76	15	by	by	ADP
cet-15446	76	16	dls	dls	PROPN
cet-15446	76	17	analysis	analysis	NOUN
cet-15446	76	18	.	.	PUNCT
cet-15446	77	1	1174	1174	NUM
cet-15446	77	2	(	(	PUNCT
cet-15446	77	3	a	a	NOUN
cet-15446	77	4	)	)	PUNCT
cet-15446	77	5	(	(	PUNCT
cet-15446	77	6	b	b	X
cet-15446	77	7	)	)	PUNCT
cet-15446	77	8	figure	figure	NOUN
cet-15446	77	9	2	2	NUM
cet-15446	77	10	:	:	PUNCT
cet-15446	77	11	fe	fe	ADJ
cet-15446	77	12	-	-	ADJ
cet-15446	77	13	sem	sem	NOUN
cet-15446	77	14	images	image	NOUN
cet-15446	77	15	of	of	ADP
cet-15446	77	16	empty	empty	ADJ
cet-15446	77	17	transfersomes	transfersome	NOUN
cet-15446	77	18	(	(	PUNCT
cet-15446	77	19	a	a	NOUN
cet-15446	77	20	)	)	PUNCT
cet-15446	77	21	and	and	CCONJ
cet-15446	77	22	diclofenac	diclofenac	NOUN
cet-15446	77	23	-	-	PUNCT
cet-15446	77	24	loaded	load	VERB
cet-15446	77	25	transfersomes	transfersome	NOUN
cet-15446	77	26	(	(	PUNCT
cet-15446	77	27	b	b	NOUN
cet-15446	77	28	)	)	PUNCT
cet-15446	77	29	3.3	3.3	NUM
cet-15446	77	30	drug	drug	NOUN
cet-15446	77	31	release	release	NOUN
cet-15446	77	32	tests	test	NOUN
cet-15446	77	33	figure	figure	VERB
cet-15446	77	34	3	3	NUM
cet-15446	77	35	shows	show	VERB
cet-15446	77	36	release	release	NOUN
cet-15446	77	37	profiles	profile	NOUN
cet-15446	77	38	of	of	ADP
cet-15446	77	39	diclofenac	diclofenac	ADJ
cet-15446	77	40	powder	powder	NOUN
cet-15446	77	41	and	and	CCONJ
cet-15446	77	42	diclofenac	diclofenac	NOUN
cet-15446	77	43	-	-	PUNCT
cet-15446	77	44	loaded	load	VERB
cet-15446	77	45	transfersomes	transfersome	NOUN
cet-15446	77	46	,	,	PUNCT
cet-15446	77	47	expressed	express	VERB
cet-15446	77	48	in	in	ADP
cet-15446	77	49	terms	term	NOUN
cet-15446	77	50	of	of	ADP
cet-15446	77	51	drug	drug	NOUN
cet-15446	77	52	concentration	concentration	NOUN
cet-15446	77	53	(	(	PUNCT
cet-15446	77	54	ct	ct	NOUN
cet-15446	77	55	/	/	SYM
cet-15446	77	56	ceq	ceq	ADJ
cet-15446	77	57	)	)	PUNCT
cet-15446	77	58	against	against	ADP
cet-15446	77	59	time	time	NOUN
cet-15446	77	60	(	(	PUNCT
cet-15446	77	61	min	min	NOUN
cet-15446	77	62	)	)	PUNCT
cet-15446	77	63	.	.	PUNCT
cet-15446	78	1	in	in	ADP
cet-15446	78	2	particular	particular	ADJ
cet-15446	78	3	,	,	PUNCT
cet-15446	78	4	ct	ct	PROPN
cet-15446	78	5	is	be	AUX
cet-15446	78	6	the	the	DET
cet-15446	78	7	drug	drug	NOUN
cet-15446	78	8	concentration	concentration	NOUN
cet-15446	78	9	measured	measure	VERB
cet-15446	78	10	at	at	ADP
cet-15446	78	11	a	a	DET
cet-15446	78	12	specific	specific	ADJ
cet-15446	78	13	time	time	NOUN
cet-15446	78	14	;	;	PUNCT
cet-15446	78	15	ceq	ceq	ADJ
cet-15446	78	16	is	be	AUX
cet-15446	78	17	the	the	DET
cet-15446	78	18	maximum	maximum	ADJ
cet-15446	78	19	drug	drug	NOUN
cet-15446	78	20	concentration	concentration	NOUN
cet-15446	78	21	released	release	VERB
cet-15446	78	22	.	.	PUNCT
cet-15446	79	1	figure	figure	VERB
cet-15446	79	2	3	3	NUM
cet-15446	79	3	:	:	PUNCT
cet-15446	79	4	diclofenac	diclofenac	NOUN
cet-15446	79	5	release	release	NOUN
cet-15446	79	6	profiles	profile	NOUN
cet-15446	79	7	for	for	ADP
cet-15446	79	8	diclofenac	diclofenac	ADJ
cet-15446	79	9	powder	powder	NOUN
cet-15446	79	10	and	and	CCONJ
cet-15446	79	11	diclofenac	diclofenac	NOUN
cet-15446	79	12	-	-	PUNCT
cet-15446	79	13	loaded	load	VERB
cet-15446	79	14	into	into	ADP
cet-15446	79	15	transfersomes	transfersome	NOUN
cet-15446	79	16	.	.	PUNCT
cet-15446	80	1	lines	line	NOUN
cet-15446	80	2	highlight	highlight	VERB
cet-15446	80	3	the	the	DET
cet-15446	80	4	general	general	ADJ
cet-15446	80	5	drug	drug	NOUN
cet-15446	80	6	release	release	NOUN
cet-15446	80	7	profile	profile	NOUN
cet-15446	80	8	.	.	PUNCT
cet-15446	81	1	these	these	DET
cet-15446	81	2	results	result	NOUN
cet-15446	81	3	show	show	VERB
cet-15446	81	4	that	that	SCONJ
cet-15446	81	5	the	the	DET
cet-15446	81	6	diclofenac	diclofenac	ADJ
cet-15446	81	7	powder	powder	NOUN
cet-15446	81	8	was	be	AUX
cet-15446	81	9	dissolved	dissolve	VERB
cet-15446	81	10	in	in	ADP
cet-15446	81	11	the	the	DET
cet-15446	81	12	pbs	pbs	PROPN
cet-15446	81	13	release	release	NOUN
cet-15446	81	14	medium	medium	NOUN
cet-15446	81	15	in	in	ADP
cet-15446	81	16	about	about	ADV
cet-15446	81	17	1	1	NUM
cet-15446	81	18	day	day	NOUN
cet-15446	81	19	;	;	PUNCT
cet-15446	81	20	whereas	whereas	ADV
cet-15446	81	21	,	,	PUNCT
cet-15446	81	22	diclofenac	diclofenac	NOUN
cet-15446	81	23	loaded	load	VERB
cet-15446	81	24	into	into	ADP
cet-15446	81	25	transfersomes	transfersome	NOUN
cet-15446	81	26	was	be	AUX
cet-15446	81	27	released	release	VERB
cet-15446	81	28	in	in	ADP
cet-15446	81	29	about	about	ADV
cet-15446	81	30	4	4	NUM
cet-15446	81	31	days	day	NOUN
cet-15446	81	32	.	.	PUNCT
cet-15446	82	1	this	this	DET
cet-15446	82	2	result	result	NOUN
cet-15446	82	3	underlines	underline	VERB
cet-15446	82	4	that	that	SCONJ
cet-15446	82	5	diclofenac	diclofenac	NOUN
cet-15446	82	6	encapsulated	encapsulate	VERB
cet-15446	82	7	into	into	ADP
cet-15446	82	8	transfersomes	transfersome	NOUN
cet-15446	82	9	was	be	AUX
cet-15446	82	10	released	release	VERB
cet-15446	82	11	slowly	slowly	ADV
cet-15446	82	12	compared	compare	VERB
cet-15446	82	13	with	with	ADP
cet-15446	82	14	the	the	DET
cet-15446	82	15	drug	drug	NOUN
cet-15446	82	16	alone	alone	ADV
cet-15446	82	17	,	,	PUNCT
cet-15446	82	18	since	since	SCONJ
cet-15446	82	19	the	the	DET
cet-15446	82	20	deformable	deformable	ADJ
cet-15446	82	21	bilayer	bilayer	NOUN
cet-15446	82	22	of	of	ADP
cet-15446	82	23	nanovesicles	nanovesicle	NOUN
cet-15446	82	24	acted	act	VERB
cet-15446	82	25	as	as	ADP
cet-15446	82	26	a	a	DET
cet-15446	82	27	barrier	barrier	NOUN
cet-15446	82	28	,	,	PUNCT
cet-15446	82	29	prolonging	prolong	VERB
cet-15446	82	30	the	the	DET
cet-15446	82	31	release	release	NOUN
cet-15446	82	32	time	time	NOUN
cet-15446	82	33	of	of	ADP
cet-15446	82	34	the	the	DET
cet-15446	82	35	drug	drug	NOUN
cet-15446	82	36	and	and	CCONJ
cet-15446	82	37	protecting	protect	VERB
cet-15446	82	38	it	it	PRON
cet-15446	82	39	from	from	ADP
cet-15446	82	40	fast	fast	ADJ
cet-15446	82	41	degradation	degradation	NOUN
cet-15446	82	42	.	.	PUNCT
cet-15446	83	1	therefore	therefore	ADV
cet-15446	83	2	,	,	PUNCT
cet-15446	83	3	the	the	DET
cet-15446	83	4	encapsulation	encapsulation	NOUN
cet-15446	83	5	of	of	ADP
cet-15446	83	6	diclofenac	diclofenac	NOUN
cet-15446	83	7	within	within	ADP
cet-15446	83	8	transfersomes	transfersome	NOUN
cet-15446	83	9	can	can	AUX
cet-15446	83	10	improve	improve	VERB
cet-15446	83	11	drug	drug	NOUN
cet-15446	83	12	bioavailability	bioavailability	NOUN
cet-15446	83	13	,	,	PUNCT
cet-15446	83	14	ensuring	ensure	VERB
cet-15446	83	15	its	its	PRON
cet-15446	83	16	stability	stability	NOUN
cet-15446	83	17	for	for	ADP
cet-15446	83	18	a	a	DET
cet-15446	83	19	longer	long	ADJ
cet-15446	83	20	period	period	NOUN
cet-15446	83	21	and	and	CCONJ
cet-15446	83	22	reducing	reduce	VERB
cet-15446	83	23	the	the	DET
cet-15446	83	24	frequency	frequency	NOUN
cet-15446	83	25	of	of	ADP
cet-15446	83	26	drug	drug	NOUN
cet-15446	83	27	administration	administration	NOUN
cet-15446	83	28	.	.	PUNCT
cet-15446	84	1	4	4	X
cet-15446	84	2	.	.	X
cet-15446	84	3	conclusions	conclusion	NOUN
cet-15446	84	4	this	this	DET
cet-15446	84	5	work	work	NOUN
cet-15446	84	6	showed	show	VERB
cet-15446	84	7	that	that	SCONJ
cet-15446	84	8	transfersomes	transfersome	NOUN
cet-15446	84	9	produced	produce	VERB
cet-15446	84	10	by	by	ADP
cet-15446	84	11	supersomes	supersome	NOUN
cet-15446	84	12	process	process	NOUN
cet-15446	84	13	were	be	AUX
cet-15446	84	14	characterized	characterize	VERB
cet-15446	84	15	by	by	ADP
cet-15446	84	16	a	a	DET
cet-15446	84	17	nanometric	nanometric	ADJ
cet-15446	84	18	diameter	diameter	NOUN
cet-15446	84	19	and	and	CCONJ
cet-15446	84	20	a	a	DET
cet-15446	84	21	unimodal	unimodal	ADJ
cet-15446	84	22	size	size	NOUN
cet-15446	84	23	distribution	distribution	NOUN
cet-15446	84	24	,	,	PUNCT
cet-15446	84	25	without	without	ADP
cet-15446	84	26	using	use	VERB
cet-15446	84	27	post	post	ADJ
cet-15446	84	28	-	-	ADJ
cet-15446	84	29	processing	processing	ADJ
cet-15446	84	30	operations	operation	NOUN
cet-15446	84	31	.	.	PUNCT
cet-15446	85	1	fe	fe	X
cet-15446	85	2	-	-	ADJ
cet-15446	85	3	sem	sem	NOUN
cet-15446	85	4	analysis	analysis	NOUN
cet-15446	85	5	confirmed	confirm	VERB
cet-15446	85	6	the	the	DET
cet-15446	85	7	spherical	spherical	ADJ
cet-15446	85	8	and	and	CCONJ
cet-15446	85	9	regular	regular	ADJ
cet-15446	85	10	morphology	morphology	NOUN
cet-15446	85	11	of	of	ADP
cet-15446	85	12	these	these	DET
cet-15446	85	13	nanovesicles	nanovesicle	NOUN
cet-15446	85	14	.	.	PUNCT
cet-15446	86	1	an	an	DET
cet-15446	86	2	encapsulation	encapsulation	NOUN
cet-15446	86	3	efficiency	efficiency	NOUN
cet-15446	86	4	of	of	ADP
cet-15446	86	5	74	74	NUM
cet-15446	86	6	%	%	NOUN
cet-15446	86	7	was	be	AUX
cet-15446	86	8	obtained	obtain	VERB
cet-15446	86	9	when	when	SCONJ
cet-15446	86	10	diclofenac	diclofenac	ADJ
cet-15446	86	11	sodium	sodium	NOUN
cet-15446	86	12	was	be	AUX
cet-15446	86	13	entrapped	entrap	VERB
cet-15446	86	14	into	into	ADP
cet-15446	86	15	the	the	DET
cet-15446	86	16	optimized	optimize	VERB
cet-15446	86	17	formulation	formulation	NOUN
cet-15446	86	18	of	of	ADP
cet-15446	86	19	transfersomes	transfersome	NOUN
cet-15446	86	20	.	.	PUNCT
cet-15446	87	1	1175	1175	NUM
cet-15446	87	2	drug	drug	NOUN
cet-15446	87	3	release	release	NOUN
cet-15446	87	4	tests	test	NOUN
cet-15446	87	5	also	also	ADV
cet-15446	87	6	underlined	underline	VERB
cet-15446	87	7	that	that	SCONJ
cet-15446	87	8	a	a	DET
cet-15446	87	9	slower	slow	ADJ
cet-15446	87	10	release	release	NOUN
cet-15446	87	11	kinetic	kinetic	NOUN
cet-15446	87	12	can	can	AUX
cet-15446	87	13	be	be	AUX
cet-15446	87	14	obtained	obtain	VERB
cet-15446	87	15	after	after	ADP
cet-15446	87	16	the	the	DET
cet-15446	87	17	encapsulation	encapsulation	NOUN
cet-15446	87	18	of	of	ADP
cet-15446	87	19	diclofenac	diclofenac	NOUN
cet-15446	87	20	into	into	ADP
cet-15446	87	21	nanometric	nanometric	ADJ
cet-15446	87	22	transfersomes	transfersome	NOUN
cet-15446	87	23	;	;	PUNCT
cet-15446	87	24	whereas	whereas	SCONJ
cet-15446	87	25	deformability	deformability	NOUN
cet-15446	87	26	tests	test	NOUN
cet-15446	87	27	confirmed	confirm	VERB
cet-15446	87	28	the	the	DET
cet-15446	87	29	efficiency	efficiency	NOUN
cet-15446	87	30	of	of	ADP
cet-15446	87	31	supersomes	supersome	NOUN
cet-15446	87	32	process	process	NOUN
cet-15446	87	33	.	.	PUNCT
cet-15446	88	1	acknowledgments	acknowledgment	NOUN
cet-15446	88	2	sonia	sonia	PROPN
cet-15446	88	3	sarnelli	sarnelli	PROPN
cet-15446	88	4	:	:	PUNCT
cet-15446	88	5	writing	writing	NOUN
cet-15446	88	6	–	–	PUNCT
cet-15446	88	7	review	review	NOUN
cet-15446	88	8	&	&	CCONJ
cet-15446	88	9	editing	editing	PROPN
cet-15446	88	10	,	,	PUNCT
cet-15446	88	11	writing	writing	NOUN
cet-15446	88	12	–	–	PUNCT
cet-15446	88	13	original	original	ADJ
cet-15446	88	14	draft	draft	NOUN
cet-15446	88	15	,	,	PUNCT
cet-15446	88	16	investigation	investigation	NOUN
cet-15446	88	17	,	,	PUNCT
cet-15446	88	18	formal	formal	ADJ
cet-15446	88	19	analysis	analysis	NOUN
cet-15446	88	20	.	.	PUNCT
cet-15446	89	1	ernesto	ernesto	PROPN
cet-15446	89	2	reverchon	reverchon	PROPN
cet-15446	89	3	:	:	PUNCT
cet-15446	89	4	writing	writing	NOUN
cet-15446	89	5	–	–	PUNCT
cet-15446	89	6	review	review	NOUN
cet-15446	89	7	&	&	CCONJ
cet-15446	89	8	editing	editing	NOUN
cet-15446	89	9	,	,	PUNCT
cet-15446	89	10	visualization	visualization	NOUN
cet-15446	89	11	,	,	PUNCT
cet-15446	89	12	supervision	supervision	NOUN
cet-15446	89	13	,	,	PUNCT
cet-15446	89	14	resources	resource	NOUN
cet-15446	89	15	.	.	PUNCT
cet-15446	90	1	lucia	lucia	PROPN
cet-15446	90	2	baldino	baldino	PROPN
cet-15446	90	3	:	:	PUNCT
cet-15446	90	4	writing	writing	NOUN
cet-15446	90	5	–	–	PUNCT
cet-15446	90	6	review	review	NOUN
cet-15446	90	7	&	&	CCONJ
cet-15446	90	8	editing	editing	PROPN
cet-15446	90	9	,	,	PUNCT
cet-15446	90	10	writing	writing	NOUN
cet-15446	90	11	–	–	PUNCT
cet-15446	90	12	original	original	ADJ
cet-15446	90	13	draft	draft	NOUN
cet-15446	90	14	,	,	PUNCT
cet-15446	90	15	visualization	visualization	NOUN
cet-15446	90	16	,	,	PUNCT
cet-15446	90	17	validation	validation	NOUN
cet-15446	90	18	,	,	PUNCT
cet-15446	90	19	supervision	supervision	NOUN
cet-15446	90	20	,	,	PUNCT
cet-15446	90	21	methodology	methodology	NOUN
cet-15446	90	22	,	,	PUNCT
cet-15446	90	23	conceptualization	conceptualization	NOUN
cet-15446	90	24	.	.	PUNCT
cet-15446	91	1	references	reference	NOUN
cet-15446	91	2	baldino	baldino	PROPN
cet-15446	91	3	,	,	PUNCT
cet-15446	91	4	l.	l.	PROPN
cet-15446	91	5	,	,	PUNCT
cet-15446	91	6	reverchon	reverchon	PROPN
cet-15446	91	7	,	,	PUNCT
cet-15446	91	8	e.	e.	PROPN
cet-15446	91	9	,	,	PUNCT
cet-15446	91	10	2022	2022	NUM
cet-15446	91	11	,	,	PUNCT
cet-15446	91	12	continuous	continuous	ADJ
cet-15446	91	13	supercritical	supercritical	ADJ
cet-15446	91	14	co2	co2	NOUN
cet-15446	91	15	assisted	assist	VERB
cet-15446	91	16	process	process	NOUN
cet-15446	91	17	for	for	ADP
cet-15446	91	18	the	the	DET
cet-15446	91	19	production	production	NOUN
cet-15446	91	20	of	of	ADP
cet-15446	91	21	nanoniosomes	nanoniosome	NOUN
cet-15446	91	22	loaded	load	VERB
cet-15446	91	23	with	with	ADP
cet-15446	91	24	a	a	DET
cet-15446	91	25	second	second	ADJ
cet-15446	91	26	-	-	PUNCT
cet-15446	91	27	generation	generation	NOUN
cet-15446	91	28	antibiotic	antibiotic	NOUN
cet-15446	91	29	for	for	ADP
cet-15446	91	30	ocular	ocular	ADJ
cet-15446	91	31	therapy	therapy	NOUN
cet-15446	91	32	,	,	PUNCT
cet-15446	91	33	the	the	DET
cet-15446	91	34	journal	journal	NOUN
cet-15446	91	35	of	of	ADP
cet-15446	91	36	supercritical	supercritical	ADJ
cet-15446	91	37	fluids	fluid	NOUN
cet-15446	91	38	,	,	PUNCT
cet-15446	91	39	188	188	NUM
cet-15446	91	40	,	,	PUNCT
cet-15446	91	41	105673	105673	NUM
cet-15446	91	42	.	.	PUNCT
cet-15446	92	1	baldino	baldino	PROPN
cet-15446	92	2	,	,	PUNCT
cet-15446	92	3	l.	l.	PROPN
cet-15446	92	4	,	,	PUNCT
cet-15446	92	5	reverchon	reverchon	PROPN
cet-15446	92	6	,	,	PUNCT
cet-15446	92	7	e.	e.	PROPN
cet-15446	92	8	,	,	PUNCT
cet-15446	92	9	2023	2023	NUM
cet-15446	92	10	,	,	PUNCT
cet-15446	92	11	production	production	NOUN
cet-15446	92	12	of	of	ADP
cet-15446	92	13	nanoliposomes	nanoliposome	NOUN
cet-15446	92	14	by	by	ADP
cet-15446	92	15	a	a	DET
cet-15446	92	16	supercritical	supercritical	ADJ
cet-15446	92	17	co2	co2	NOUN
cet-15446	92	18	assisted	assist	VERB
cet-15446	92	19	process	process	NOUN
cet-15446	92	20	:	:	PUNCT
cet-15446	92	21	application	application	NOUN
cet-15446	92	22	to	to	ADP
cet-15446	92	23	cosmetics	cosmetic	NOUN
cet-15446	92	24	,	,	PUNCT
cet-15446	92	25	chemical	chemical	NOUN
cet-15446	92	26	engineering	engineering	NOUN
cet-15446	92	27	transactions	transaction	NOUN
cet-15446	92	28	,	,	PUNCT
cet-15446	92	29	101	101	NUM
cet-15446	92	30	,	,	PUNCT
cet-15446	92	31	61	61	NUM
cet-15446	92	32	-	-	SYM
cet-15446	92	33	66	66	NUM
cet-15446	92	34	.	.	PUNCT
cet-15446	93	1	bucci	bucci	PROPN
cet-15446	93	2	,	,	PUNCT
cet-15446	93	3	r.	r.	PROPN
cet-15446	93	4	,	,	PUNCT
cet-15446	93	5	magri	magri	NOUN
cet-15446	93	6	,	,	PUNCT
cet-15446	93	7	a.d	a.d	PROPN
cet-15446	93	8	.	.	PROPN
cet-15446	93	9	,	,	PUNCT
cet-15446	93	10	magri	magri	NOUN
cet-15446	93	11	,	,	PUNCT
cet-15446	93	12	a.l	a.l	PROPN
cet-15446	93	13	.	.	PROPN
cet-15446	93	14	,	,	PUNCT
cet-15446	93	15	1998	1998	NUM
cet-15446	93	16	,	,	PUNCT
cet-15446	93	17	determination	determination	NOUN
cet-15446	93	18	of	of	ADP
cet-15446	93	19	diclofenac	diclofenac	ADJ
cet-15446	93	20	salts	salt	NOUN
cet-15446	93	21	in	in	ADP
cet-15446	93	22	pharmaceutical	pharmaceutical	NOUN
cet-15446	93	23	formulations	formulation	NOUN
cet-15446	93	24	,	,	PUNCT
cet-15446	93	25	fresenius	fresenius	PROPN
cet-15446	93	26	'	'	PUNCT
cet-15446	93	27	journal	journal	NOUN
cet-15446	93	28	of	of	ADP
cet-15446	93	29	analytical	analytical	ADJ
cet-15446	93	30	chemistry	chemistry	NOUN
cet-15446	93	31	,	,	PUNCT
cet-15446	93	32	362	362	NUM
cet-15446	93	33	,	,	PUNCT
cet-15446	93	34	577	577	NUM
cet-15446	93	35	-	-	SYM
cet-15446	93	36	582	582	NUM
cet-15446	93	37	.	.	PUNCT
cet-15446	94	1	cevc	cevc	PROPN
cet-15446	94	2	,	,	PUNCT
cet-15446	94	3	g.	g.	PROPN
cet-15446	94	4	,	,	PUNCT
cet-15446	94	5	blume	blume	PROPN
cet-15446	94	6	,	,	PUNCT
cet-15446	94	7	g.	g.	PROPN
cet-15446	94	8	,	,	PUNCT
cet-15446	94	9	2001	2001	NUM
cet-15446	94	10	,	,	PUNCT
cet-15446	94	11	new	new	ADJ
cet-15446	94	12	,	,	PUNCT
cet-15446	94	13	highly	highly	ADV
cet-15446	94	14	efficient	efficient	ADJ
cet-15446	94	15	formulation	formulation	NOUN
cet-15446	94	16	of	of	ADP
cet-15446	94	17	diclofenac	diclofenac	NOUN
cet-15446	94	18	for	for	ADP
cet-15446	94	19	the	the	DET
cet-15446	94	20	topical	topical	ADJ
cet-15446	94	21	,	,	PUNCT
cet-15446	94	22	transdermal	transdermal	ADJ
cet-15446	94	23	administration	administration	NOUN
cet-15446	94	24	in	in	ADP
cet-15446	94	25	ultradeformable	ultradeformable	ADJ
cet-15446	94	26	drug	drug	NOUN
cet-15446	94	27	carriers	carrier	NOUN
cet-15446	94	28	,	,	PUNCT
cet-15446	94	29	transfersomes	transfersome	NOUN
cet-15446	94	30	.	.	PUNCT
cet-15446	95	1	biochimica	biochimica	PROPN
cet-15446	95	2	et	et	PROPN
cet-15446	95	3	biophysica	biophysica	PROPN
cet-15446	95	4	acta	acta	PROPN
cet-15446	95	5	(	(	PUNCT
cet-15446	95	6	bba)biomembranes	bba)biomembranes	PROPN
cet-15446	95	7	,	,	PUNCT
cet-15446	95	8	1514	1514	NUM
cet-15446	95	9	,	,	PUNCT
cet-15446	95	10	191	191	NUM
cet-15446	95	11	-	-	SYM
cet-15446	95	12	205	205	NUM
cet-15446	95	13	.	.	PUNCT
cet-15446	95	14	de	de	PROPN
cet-15446	95	15	a.c	a.c	PROPN
cet-15446	95	16	.	.	PROPN
cet-15446	95	17	kodel	kodel	PROPN
cet-15446	95	18	,	,	PUNCT
cet-15446	95	19	h.	h.	PROPN
cet-15446	95	20	,	,	PUNCT
cet-15446	95	21	alizadeh	alizadeh	NOUN
cet-15446	95	22	,	,	PUNCT
cet-15446	95	23	p.	p.	PROPN
cet-15446	95	24	,	,	PUNCT
cet-15446	95	25	ebrahimi	ebrahimi	PROPN
cet-15446	95	26	,	,	PUNCT
cet-15446	95	27	s.n	s.n	PROPN
cet-15446	95	28	.	.	PROPN
cet-15446	95	29	,	,	PUNCT
cet-15446	95	30	machado	machado	PROPN
cet-15446	95	31	,	,	PUNCT
cet-15446	95	32	t.o	t.o	PROPN
cet-15446	95	33	.	.	PROPN
cet-15446	95	34	,	,	PUNCT
cet-15446	95	35	oliveira	oliveira	PROPN
cet-15446	95	36	,	,	PUNCT
cet-15446	95	37	m.b.p	m.b.p	PROPN
cet-15446	95	38	.	.	PROPN
cet-15446	95	39	,	,	PUNCT
cet-15446	95	40	fathi	fathi	PROPN
cet-15446	95	41	,	,	PUNCT
cet-15446	95	42	f.	f.	PROPN
cet-15446	95	43	,	,	PUNCT
cet-15446	95	44	souto	souto	PROPN
cet-15446	95	45	,	,	PUNCT
cet-15446	95	46	e.b	e.b	PROPN
cet-15446	95	47	.	.	PROPN
cet-15446	95	48	,	,	PUNCT
cet-15446	95	49	2024	2024	NUM
cet-15446	95	50	,	,	PUNCT
cet-15446	95	51	liposomes	liposome	NOUN
cet-15446	95	52	and	and	CCONJ
cet-15446	95	53	niosomes	niosome	NOUN
cet-15446	95	54	:	:	PUNCT
cet-15446	95	55	new	new	ADJ
cet-15446	95	56	trends	trend	NOUN
cet-15446	95	57	and	and	CCONJ
cet-15446	95	58	applications	application	NOUN
cet-15446	95	59	in	in	ADP
cet-15446	95	60	the	the	DET
cet-15446	95	61	delivery	delivery	NOUN
cet-15446	95	62	of	of	ADP
cet-15446	95	63	bioactive	bioactive	ADJ
cet-15446	95	64	agents	agent	NOUN
cet-15446	95	65	for	for	ADP
cet-15446	95	66	cancer	cancer	NOUN
cet-15446	95	67	therapy	therapy	NOUN
cet-15446	95	68	,	,	PUNCT
cet-15446	95	69	international	international	ADJ
cet-15446	95	70	journal	journal	NOUN
cet-15446	95	71	of	of	ADP
cet-15446	95	72	pharmaceutics	pharmaceutic	NOUN
cet-15446	95	73	,	,	PUNCT
cet-15446	95	74	124994	124994	NUM
cet-15446	95	75	.	.	PUNCT
cet-15446	96	1	devi	devi	PROPN
cet-15446	96	2	,	,	PUNCT
cet-15446	96	3	r.s	r.s	PROPN
cet-15446	96	4	.	.	PROPN
cet-15446	96	5	,	,	PUNCT
cet-15446	96	6	narayan	narayan	PROPN
cet-15446	96	7	,	,	PUNCT
cet-15446	96	8	s.	s.	PROPN
cet-15446	96	9	,	,	PUNCT
cet-15446	96	10	vani	vani	PROPN
cet-15446	96	11	,	,	PUNCT
cet-15446	96	12	g.	g.	PROPN
cet-15446	96	13	,	,	PUNCT
cet-15446	96	14	devi	devi	PROPN
cet-15446	96	15	,	,	PUNCT
cet-15446	96	16	c.s.s	c.s.s	PROPN
cet-15446	96	17	.	.	PROPN
cet-15446	96	18	,	,	PUNCT
cet-15446	96	19	2007	2007	NUM
cet-15446	96	20	,	,	PUNCT
cet-15446	96	21	gastroprotective	gastroprotective	NOUN
cet-15446	96	22	effect	effect	NOUN
cet-15446	96	23	of	of	ADP
cet-15446	96	24	terminalia	terminalia	PROPN
cet-15446	96	25	arjuna	arjuna	PROPN
cet-15446	96	26	bark	bark	NOUN
cet-15446	96	27	on	on	ADP
cet-15446	96	28	diclofenac	diclofenac	ADJ
cet-15446	96	29	sodium	sodium	NOUN
cet-15446	96	30	induced	induce	VERB
cet-15446	96	31	gastric	gastric	ADJ
cet-15446	96	32	ulcer	ulcer	NOUN
cet-15446	96	33	,	,	PUNCT
cet-15446	96	34	chemico	chemico	NOUN
cet-15446	96	35	-	-	ADJ
cet-15446	96	36	biological	biological	ADJ
cet-15446	96	37	interactions	interaction	NOUN
cet-15446	96	38	,	,	PUNCT
cet-15446	96	39	167	167	NUM
cet-15446	96	40	,	,	PUNCT
cet-15446	96	41	71	71	NUM
cet-15446	96	42	-	-	SYM
cet-15446	96	43	83	83	NUM
cet-15446	96	44	.	.	PUNCT
cet-15446	97	1	elron	elron	NOUN
cet-15446	97	2	-	-	PUNCT
cet-15446	97	3	gross	gross	PROPN
cet-15446	97	4	,	,	PUNCT
cet-15446	97	5	i.	i.	PROPN
cet-15446	97	6	,	,	PUNCT
cet-15446	97	7	glucksam	glucksam	PROPN
cet-15446	97	8	,	,	PUNCT
cet-15446	97	9	y.	y.	PROPN
cet-15446	97	10	,	,	PUNCT
cet-15446	97	11	margalit	margalit	ADJ
cet-15446	97	12	,	,	PUNCT
cet-15446	97	13	r.	r.	PROPN
cet-15446	97	14	,	,	PUNCT
cet-15446	97	15	2009	2009	NUM
cet-15446	97	16	,	,	PUNCT
cet-15446	97	17	liposomal	liposomal	ADJ
cet-15446	97	18	dexamethasone	dexamethasone	NOUN
cet-15446	97	19	–	–	PUNCT
cet-15446	97	20	diclofenac	diclofenac	NOUN
cet-15446	97	21	combinations	combination	NOUN
cet-15446	97	22	for	for	ADP
cet-15446	97	23	local	local	ADJ
cet-15446	97	24	osteoarthritis	osteoarthritis	NOUN
cet-15446	97	25	treatment	treatment	NOUN
cet-15446	97	26	,	,	PUNCT
cet-15446	97	27	international	international	ADJ
cet-15446	97	28	journal	journal	NOUN
cet-15446	97	29	of	of	ADP
cet-15446	97	30	pharmaceutics	pharmaceutic	NOUN
cet-15446	97	31	,	,	PUNCT
cet-15446	97	32	376	376	NUM
cet-15446	97	33	,	,	PUNCT
cet-15446	97	34	84	84	NUM
cet-15446	97	35	-	-	SYM
cet-15446	97	36	91	91	NUM
cet-15446	97	37	.	.	PUNCT
cet-15446	98	1	ghaferi	ghaferi	NOUN
cet-15446	98	2	,	,	PUNCT
cet-15446	98	3	m.	m.	NOUN
cet-15446	98	4	,	,	PUNCT
cet-15446	98	5	alavi	alavi	PROPN
cet-15446	98	6	,	,	PUNCT
cet-15446	98	7	s.e	s.e	PROPN
cet-15446	98	8	.	.	PROPN
cet-15446	98	9	,	,	PUNCT
cet-15446	98	10	phan	phan	PROPN
cet-15446	98	11	,	,	PUNCT
cet-15446	98	12	k.	k.	PROPN
cet-15446	98	13	,	,	PUNCT
cet-15446	98	14	maibach	maibach	PROPN
cet-15446	98	15	,	,	PUNCT
cet-15446	98	16	h.	h.	PROPN
cet-15446	98	17	,	,	PUNCT
cet-15446	98	18	mohammed	mohammed	PROPN
cet-15446	98	19	,	,	PUNCT
cet-15446	98	20	y.	y.	PROPN
cet-15446	98	21	,	,	PUNCT
cet-15446	98	22	2024	2024	NUM
cet-15446	98	23	,	,	PUNCT
cet-15446	98	24	transdermal	transdermal	ADJ
cet-15446	98	25	drug	drug	NOUN
cet-15446	98	26	delivery	delivery	NOUN
cet-15446	98	27	systems	system	NOUN
cet-15446	98	28	(	(	PUNCT
cet-15446	98	29	tdds	tdds	PROPN
cet-15446	98	30	):	):	PUNCT
cet-15446	98	31	recent	recent	ADJ
cet-15446	98	32	advances	advance	NOUN
cet-15446	98	33	and	and	CCONJ
cet-15446	98	34	failure	failure	NOUN
cet-15446	98	35	modes	mode	NOUN
cet-15446	98	36	,	,	PUNCT
cet-15446	98	37	molecular	molecular	ADJ
cet-15446	98	38	pharmaceutics	pharmaceutic	NOUN
cet-15446	98	39	,	,	PUNCT
cet-15446	98	40	21	21	NUM
cet-15446	98	41	,	,	PUNCT
cet-15446	98	42	5373	5373	NUM
cet-15446	98	43	-	-	SYM
cet-15446	98	44	5391	5391	NUM
cet-15446	98	45	.	.	PUNCT
cet-15446	99	1	ghanbarzadeh	ghanbarzadeh	NOUN
cet-15446	99	2	,	,	PUNCT
cet-15446	99	3	s.	s.	PROPN
cet-15446	99	4	,	,	PUNCT
cet-15446	99	5	arami	arami	PROPN
cet-15446	99	6	,	,	PUNCT
cet-15446	99	7	s.	s.	PROPN
cet-15446	99	8	,	,	PUNCT
cet-15446	99	9	2013	2013	NUM
cet-15446	99	10	,	,	PUNCT
cet-15446	99	11	enhanced	enhance	VERB
cet-15446	99	12	transdermal	transdermal	ADJ
cet-15446	99	13	delivery	delivery	NOUN
cet-15446	99	14	of	of	ADP
cet-15446	99	15	diclofenac	diclofenac	ADJ
cet-15446	99	16	sodium	sodium	NOUN
cet-15446	99	17	via	via	ADP
cet-15446	99	18	conventional	conventional	ADJ
cet-15446	99	19	liposomes	liposome	NOUN
cet-15446	99	20	,	,	PUNCT
cet-15446	99	21	ethosomes	ethosome	NOUN
cet-15446	99	22	,	,	PUNCT
cet-15446	99	23	and	and	CCONJ
cet-15446	99	24	transfersomes	transfersome	NOUN
cet-15446	99	25	,	,	PUNCT
cet-15446	99	26	biomed	biome	VERB
cet-15446	99	27	research	research	NOUN
cet-15446	99	28	international	international	PROPN
cet-15446	99	29	,	,	PUNCT
cet-15446	99	30	2013	2013	NUM
cet-15446	99	31	,	,	PUNCT
cet-15446	99	32	616810	616810	NUM
cet-15446	99	33	.	.	PUNCT
cet-15446	100	1	li	li	PROPN
cet-15446	100	2	,	,	PUNCT
cet-15446	100	3	l.	l.	PROPN
cet-15446	100	4	,	,	PUNCT
cet-15446	100	5	rossoni	rossoni	PROPN
cet-15446	100	6	,	,	PUNCT
cet-15446	100	7	g.	g.	NOUN
cet-15446	100	8	,	,	PUNCT
cet-15446	100	9	sparatore	sparatore	ADV
cet-15446	100	10	,	,	PUNCT
cet-15446	100	11	a.	a.	PROPN
cet-15446	100	12	,	,	PUNCT
cet-15446	100	13	lee	lee	PROPN
cet-15446	100	14	,	,	PUNCT
cet-15446	100	15	l.c	l.c	PROPN
cet-15446	100	16	.	.	PROPN
cet-15446	100	17	,	,	PUNCT
cet-15446	100	18	del	del	PROPN
cet-15446	100	19	soldato	soldato	PROPN
cet-15446	100	20	,	,	PUNCT
cet-15446	100	21	p.	p.	PROPN
cet-15446	100	22	,	,	PUNCT
cet-15446	100	23	moore	moore	PROPN
cet-15446	100	24	,	,	PUNCT
cet-15446	100	25	p.k	p.k	PROPN
cet-15446	100	26	.	.	PROPN
cet-15446	100	27	,	,	PUNCT
cet-15446	100	28	2007	2007	NUM
cet-15446	100	29	,	,	PUNCT
cet-15446	100	30	anti	anti	ADJ
cet-15446	100	31	-	-	ADJ
cet-15446	100	32	inflammatory	inflammatory	ADJ
cet-15446	100	33	and	and	CCONJ
cet-15446	100	34	gastrointestinal	gastrointestinal	ADJ
cet-15446	100	35	effects	effect	NOUN
cet-15446	100	36	of	of	ADP
cet-15446	100	37	a	a	DET
cet-15446	100	38	novel	novel	ADJ
cet-15446	100	39	diclofenac	diclofenac	NOUN
cet-15446	100	40	derivative	derivative	NOUN
cet-15446	100	41	,	,	PUNCT
cet-15446	100	42	free	free	ADJ
cet-15446	100	43	radical	radical	ADJ
cet-15446	100	44	biology	biology	NOUN
cet-15446	100	45	and	and	CCONJ
cet-15446	100	46	medicine	medicine	NOUN
cet-15446	100	47	,	,	PUNCT
cet-15446	100	48	42	42	NUM
cet-15446	100	49	,	,	PUNCT
cet-15446	100	50	706	706	NUM
cet-15446	100	51	-	-	SYM
cet-15446	100	52	719	719	NUM
cet-15446	100	53	.	.	PUNCT
cet-15446	101	1	li	li	PROPN
cet-15446	101	2	,	,	PUNCT
cet-15446	101	3	x.	x.	PROPN
cet-15446	101	4	,	,	PUNCT
cet-15446	101	5	zhang	zhang	PROPN
cet-15446	101	6	,	,	PUNCT
cet-15446	101	7	z.	z.	PROPN
cet-15446	101	8	,	,	PUNCT
cet-15446	101	9	li	li	PROPN
cet-15446	101	10	,	,	PUNCT
cet-15446	101	11	j.	j.	PROPN
cet-15446	101	12	,	,	PUNCT
cet-15446	101	13	sun	sun	PROPN
cet-15446	101	14	,	,	PUNCT
cet-15446	101	15	s.	s.	PROPN
cet-15446	101	16	,	,	PUNCT
cet-15446	101	17	weng	weng	PROPN
cet-15446	101	18	,	,	PUNCT
cet-15446	101	19	y.	y.	PROPN
cet-15446	101	20	,	,	PUNCT
cet-15446	101	21	chen	chen	PROPN
cet-15446	101	22	,	,	PUNCT
cet-15446	101	23	h.	h.	PROPN
cet-15446	101	24	,	,	PUNCT
cet-15446	101	25	2012	2012	NUM
cet-15446	101	26	,	,	PUNCT
cet-15446	101	27	diclofenac	diclofenac	NOUN
cet-15446	101	28	/	/	SYM
cet-15446	101	29	biodegradable	biodegradable	ADJ
cet-15446	101	30	polymer	polymer	NOUN
cet-15446	101	31	micelles	micelle	NOUN
cet-15446	101	32	for	for	ADP
cet-15446	101	33	ocular	ocular	ADJ
cet-15446	101	34	applications	application	NOUN
cet-15446	101	35	,	,	PUNCT
cet-15446	101	36	nanoscale	nanoscale	NOUN
cet-15446	101	37	,	,	PUNCT
cet-15446	101	38	4	4	NUM
cet-15446	101	39	,	,	PUNCT
cet-15446	101	40	4667	4667	NUM
cet-15446	101	41	-	-	SYM
cet-15446	101	42	4673	4673	NUM
cet-15446	101	43	.	.	PUNCT
cet-15446	102	1	matharoo	matharoo	PROPN
cet-15446	102	2	,	,	PUNCT
cet-15446	102	3	n.	n.	PROPN
cet-15446	102	4	,	,	PUNCT
cet-15446	102	5	mohd	mohd	PROPN
cet-15446	102	6	,	,	PUNCT
cet-15446	102	7	h.	h.	PROPN
cet-15446	102	8	,	,	PUNCT
cet-15446	102	9	michniak‐kohn	michniak‐kohn	PROPN
cet-15446	102	10	,	,	PUNCT
cet-15446	102	11	b.	b.	PROPN
cet-15446	102	12	,	,	PUNCT
cet-15446	102	13	2024	2024	NUM
cet-15446	102	14	,	,	PUNCT
cet-15446	102	15	transferosomes	transferosome	NOUN
cet-15446	102	16	as	as	ADP
cet-15446	102	17	a	a	DET
cet-15446	102	18	transdermal	transdermal	ADJ
cet-15446	102	19	drug	drug	NOUN
cet-15446	102	20	delivery	delivery	NOUN
cet-15446	102	21	system	system	NOUN
cet-15446	102	22	:	:	PUNCT
cet-15446	102	23	dermal	dermal	ADJ
cet-15446	102	24	kinetics	kinetic	NOUN
cet-15446	102	25	and	and	CCONJ
cet-15446	102	26	recent	recent	ADJ
cet-15446	102	27	developments	development	NOUN
cet-15446	102	28	,	,	PUNCT
cet-15446	102	29	wiley	wiley	NOUN
cet-15446	102	30	interdisciplinary	interdisciplinary	ADJ
cet-15446	102	31	reviews	review	NOUN
cet-15446	102	32	:	:	PUNCT
cet-15446	102	33	nanomedicine	nanomedicine	NOUN
cet-15446	102	34	and	and	CCONJ
cet-15446	102	35	nanobiotechnology	nanobiotechnology	NOUN
cet-15446	102	36	,	,	PUNCT
cet-15446	102	37	16	16	NUM
cet-15446	102	38	,	,	PUNCT
cet-15446	102	39	e1918	e1918	PROPN
cet-15446	102	40	.	.	PUNCT
cet-15446	103	1	nagaich	nagaich	PROPN
cet-15446	103	2	,	,	PUNCT
cet-15446	103	3	u.	u.	PROPN
cet-15446	103	4	,	,	PUNCT
cet-15446	103	5	mishra	mishra	PROPN
cet-15446	103	6	,	,	PUNCT
cet-15446	103	7	d.k	d.k	PROPN
cet-15446	103	8	.	.	PROPN
cet-15446	103	9	,	,	PUNCT
cet-15446	103	10	jain	jain	PROPN
cet-15446	103	11	,	,	PUNCT
cet-15446	103	12	n.	n.	NOUN
cet-15446	103	13	,	,	PUNCT
cet-15446	103	14	2024	2024	NUM
cet-15446	103	15	,	,	PUNCT
cet-15446	103	16	full	full	ADJ
cet-15446	103	17	factorial	factorial	ADJ
cet-15446	103	18	design	design	NOUN
cet-15446	103	19	-	-	PUNCT
cet-15446	103	20	based	base	VERB
cet-15446	103	21	development	development	NOUN
cet-15446	103	22	and	and	CCONJ
cet-15446	103	23	characterization	characterization	NOUN
cet-15446	103	24	of	of	ADP
cet-15446	103	25	ciclopirox	ciclopirox	PROPN
cet-15446	103	26	olamine	olamine	PROPN
cet-15446	103	27	loaded	load	VERB
cet-15446	103	28	transferosomes	transferosome	NOUN
cet-15446	103	29	:	:	PUNCT
cet-15446	103	30	an	an	DET
cet-15446	103	31	efficient	efficient	ADJ
cet-15446	103	32	approach	approach	NOUN
cet-15446	103	33	for	for	ADP
cet-15446	103	34	the	the	DET
cet-15446	103	35	management	management	NOUN
cet-15446	103	36	of	of	ADP
cet-15446	103	37	athlete	athlete	NOUN
cet-15446	103	38	's	's	PART
cet-15446	103	39	foot	foot	NOUN
cet-15446	103	40	,	,	PUNCT
cet-15446	103	41	journal	journal	NOUN
cet-15446	103	42	of	of	ADP
cet-15446	103	43	drug	drug	NOUN
cet-15446	103	44	delivery	delivery	NOUN
cet-15446	103	45	science	science	NOUN
cet-15446	103	46	and	and	CCONJ
cet-15446	103	47	technology	technology	NOUN
cet-15446	103	48	,	,	PUNCT
cet-15446	103	49	99	99	NUM
cet-15446	103	50	,	,	PUNCT
cet-15446	103	51	105939	105939	NUM
cet-15446	103	52	.	.	PUNCT
cet-15446	104	1	patel	patel	PROPN
cet-15446	104	2	,	,	PUNCT
cet-15446	104	3	s.	s.	PROPN
cet-15446	104	4	,	,	PUNCT
cet-15446	104	5	ismail	ismail	PROPN
cet-15446	104	6	,	,	PUNCT
cet-15446	104	7	y.	y.	PROPN
cet-15446	104	8	,	,	PUNCT
cet-15446	104	9	singh	singh	PROPN
cet-15446	104	10	,	,	PUNCT
cet-15446	104	11	s.	s.	PROPN
cet-15446	104	12	,	,	PUNCT
cet-15446	104	13	rathi	rathi	PROPN
cet-15446	104	14	,	,	PUNCT
cet-15446	104	15	s.	s.	PROPN
cet-15446	104	16	,	,	PUNCT
cet-15446	104	17	shakya	shakya	PROPN
cet-15446	104	18	,	,	PUNCT
cet-15446	104	19	s.	s.	PROPN
cet-15446	104	20	,	,	PUNCT
cet-15446	104	21	patil	patil	PROPN
cet-15446	104	22	,	,	PUNCT
cet-15446	104	23	s.s	s.s	PROPN
cet-15446	104	24	.	.	PROPN
cet-15446	104	25	,	,	PUNCT
cet-15446	104	26	bumrela	bumrela	PROPN
cet-15446	104	27	,	,	PUNCT
cet-15446	104	28	s.	s.	PROPN
cet-15446	104	29	,	,	PUNCT
cet-15446	104	30	jain	jain	PROPN
cet-15446	104	31	,	,	PUNCT
cet-15446	104	32	p.c	p.c	PROPN
cet-15446	104	33	.	.	PROPN
cet-15446	104	34	,	,	PUNCT
cet-15446	104	35	goswami	goswami	PROPN
cet-15446	104	36	,	,	PUNCT
cet-15446	104	37	p.	p.	PROPN
cet-15446	104	38	,	,	PUNCT
cet-15446	104	39	singh	singh	PROPN
cet-15446	104	40	,	,	PUNCT
cet-15446	104	41	s.	s.	PROPN
cet-15446	104	42	,	,	PUNCT
cet-15446	104	43	2024	2024	NUM
cet-15446	104	44	,	,	PUNCT
cet-15446	104	45	recent	recent	ADJ
cet-15446	104	46	innovations	innovation	NOUN
cet-15446	104	47	and	and	CCONJ
cet-15446	104	48	future	future	ADJ
cet-15446	104	49	perspectives	perspective	NOUN
cet-15446	104	50	in	in	ADP
cet-15446	104	51	transferosomes	transferosome	NOUN
cet-15446	104	52	for	for	ADP
cet-15446	104	53	transdermal	transdermal	ADJ
cet-15446	104	54	drug	drug	NOUN
cet-15446	104	55	delivery	delivery	NOUN
cet-15446	104	56	in	in	ADP
cet-15446	104	57	therapeutic	therapeutic	ADJ
cet-15446	104	58	and	and	CCONJ
cet-15446	104	59	pharmacological	pharmacological	ADJ
cet-15446	104	60	applications	application	NOUN
cet-15446	104	61	,	,	PUNCT
cet-15446	104	62	zhongguo	zhongguo	PROPN
cet-15446	104	63	ying	ying	PROPN
cet-15446	104	64	yong	yong	PROPN
cet-15446	104	65	sheng	sheng	PROPN
cet-15446	104	66	li	li	PROPN
cet-15446	104	67	xue	xue	PROPN
cet-15446	104	68	za	za	PROPN
cet-15446	104	69	zhi	zhi	PROPN
cet-15446	104	70	,	,	PUNCT
cet-15446	104	71	40	40	NUM
cet-15446	104	72	,	,	PUNCT
cet-15446	104	73	e20240031	e20240031	NOUN
cet-15446	104	74	.	.	PUNCT
cet-15446	105	1	prausnitz	prausnitz	PROPN
cet-15446	105	2	,	,	PUNCT
cet-15446	105	3	m.r	m.r	PROPN
cet-15446	105	4	.	.	PROPN
cet-15446	105	5	,	,	PUNCT
cet-15446	105	6	langer	langer	PROPN
cet-15446	105	7	,	,	PUNCT
cet-15446	105	8	r.	r.	PROPN
cet-15446	105	9	,	,	PUNCT
cet-15446	105	10	2008	2008	NUM
cet-15446	105	11	,	,	PUNCT
cet-15446	105	12	transdermal	transdermal	ADJ
cet-15446	105	13	drug	drug	NOUN
cet-15446	105	14	delivery	delivery	NOUN
cet-15446	105	15	,	,	PUNCT
cet-15446	105	16	nature	nature	NOUN
cet-15446	105	17	biotechnology	biotechnology	NOUN
cet-15446	105	18	,	,	PUNCT
cet-15446	105	19	26	26	NUM
cet-15446	105	20	,	,	PUNCT
cet-15446	105	21	1261	1261	NUM
cet-15446	105	22	-	-	SYM
cet-15446	105	23	1268	1268	NUM
cet-15446	105	24	.	.	PUNCT
cet-15446	106	1	squittieri	squittieri	PROPN
cet-15446	106	2	,	,	PUNCT
cet-15446	106	3	r.	r.	PROPN
cet-15446	106	4	,	,	PUNCT
cet-15446	106	5	baldino	baldino	PROPN
cet-15446	106	6	,	,	PUNCT
cet-15446	106	7	l.	l.	PROPN
cet-15446	106	8	,	,	PUNCT
cet-15446	106	9	reverchon	reverchon	PROPN
cet-15446	106	10	,	,	PUNCT
cet-15446	106	11	e.	e.	PROPN
cet-15446	106	12	,	,	PUNCT
cet-15446	106	13	2023	2023	NUM
cet-15446	106	14	,	,	PUNCT
cet-15446	106	15	production	production	NOUN
cet-15446	106	16	of	of	ADP
cet-15446	106	17	antioxidant	antioxidant	ADJ
cet-15446	106	18	transfersomes	transfersome	NOUN
cet-15446	106	19	by	by	ADP
cet-15446	106	20	a	a	DET
cet-15446	106	21	supercritical	supercritical	ADJ
cet-15446	106	22	co2	co2	NOUN
cet-15446	106	23	assisted	assist	VERB
cet-15446	106	24	process	process	NOUN
cet-15446	106	25	for	for	ADP
cet-15446	106	26	transdermal	transdermal	ADJ
cet-15446	106	27	delivery	delivery	NOUN
cet-15446	106	28	applications	application	NOUN
cet-15446	106	29	,	,	PUNCT
cet-15446	106	30	nanomaterials	nanomaterial	NOUN
cet-15446	106	31	,	,	PUNCT
cet-15446	106	32	13	13	NUM
cet-15446	106	33	,	,	PUNCT
cet-15446	106	34	1812	1812	NUM
cet-15446	106	35	.	.	PUNCT
cet-15446	107	1	sultana	sultana	NOUN
cet-15446	107	2	,	,	PUNCT
cet-15446	107	3	s.s	s.s	PROPN
cet-15446	107	4	.	.	PROPN
cet-15446	107	5	,	,	PUNCT
cet-15446	107	6	krishna	krishna	PROPN
cet-15446	107	7	sailaja	sailaja	PROPN
cet-15446	107	8	,	,	PUNCT
cet-15446	107	9	a.	a.	NOUN
cet-15446	107	10	,	,	PUNCT
cet-15446	107	11	2015	2015	NUM
cet-15446	107	12	,	,	PUNCT
cet-15446	107	13	formulation	formulation	NOUN
cet-15446	107	14	and	and	CCONJ
cet-15446	107	15	evaluation	evaluation	NOUN
cet-15446	107	16	of	of	ADP
cet-15446	107	17	diclofenac	diclofenac	ADJ
cet-15446	107	18	sodium	sodium	NOUN
cet-15446	107	19	transferosomes	transferosome	NOUN
cet-15446	107	20	using	use	VERB
cet-15446	107	21	different	different	ADJ
cet-15446	107	22	surfactants	surfactant	NOUN
cet-15446	107	23	by	by	ADP
cet-15446	107	24	thin	thin	ADJ
cet-15446	107	25	film	film	NOUN
cet-15446	107	26	hydration	hydration	NOUN
cet-15446	107	27	method	method	NOUN
cet-15446	107	28	,	,	PUNCT
cet-15446	107	29	der	der	ADJ
cet-15446	107	30	pharmacia	pharmacia	PROPN
cet-15446	107	31	lettre	lettre	PROPN
cet-15446	107	32	,	,	PUNCT
cet-15446	107	33	7	7	NUM
cet-15446	107	34	,	,	PUNCT
cet-15446	107	35	43	43	NUM
cet-15446	107	36	-	-	SYM
cet-15446	107	37	53	53	NUM
cet-15446	107	38	.	.	PUNCT
cet-15446	108	1	trucillo	trucillo	NOUN
cet-15446	108	2	,	,	PUNCT
cet-15446	108	3	p.	p.	NOUN
cet-15446	108	4	,	,	PUNCT
cet-15446	108	5	cardea	cardea	NOUN
cet-15446	108	6	,	,	PUNCT
cet-15446	108	7	s.	s.	PROPN
cet-15446	108	8	,	,	PUNCT
cet-15446	108	9	baldino	baldino	PROPN
cet-15446	108	10	,	,	PUNCT
cet-15446	108	11	l.	l.	PROPN
cet-15446	108	12	,	,	PUNCT
cet-15446	108	13	reverchon	reverchon	PROPN
cet-15446	108	14	,	,	PUNCT
cet-15446	108	15	e.	e.	PROPN
cet-15446	108	16	,	,	PUNCT
cet-15446	108	17	2020	2020	NUM
cet-15446	108	18	,	,	PUNCT
cet-15446	108	19	production	production	NOUN
cet-15446	108	20	of	of	ADP
cet-15446	108	21	liposomes	liposome	NOUN
cet-15446	108	22	loaded	load	VERB
cet-15446	108	23	alginate	alginate	NOUN
cet-15446	108	24	aerogels	aerogel	NOUN
cet-15446	108	25	using	use	VERB
cet-15446	108	26	two	two	NUM
cet-15446	108	27	supercritical	supercritical	ADJ
cet-15446	108	28	co2	co2	NOUN
cet-15446	108	29	assisted	assist	VERB
cet-15446	108	30	techniques	technique	NOUN
cet-15446	108	31	,	,	PUNCT
cet-15446	108	32	journal	journal	NOUN
cet-15446	108	33	of	of	ADP
cet-15446	108	34	co2	co2	NOUN
cet-15446	108	35	utilization	utilization	NOUN
cet-15446	108	36	,	,	PUNCT
cet-15446	108	37	39	39	NUM
cet-15446	108	38	,	,	PUNCT
cet-15446	108	39	101161	101161	NUM
cet-15446	108	40	.	.	PUNCT
cet-15446	109	1	wadher	wadher	PROPN
cet-15446	109	2	,	,	PUNCT
cet-15446	109	3	k.	k.	PROPN
cet-15446	109	4	,	,	PUNCT
cet-15446	109	5	trivedi	trivedi	PROPN
cet-15446	109	6	,	,	PUNCT
cet-15446	109	7	s.	s.	PROPN
cet-15446	109	8	,	,	PUNCT
cet-15446	109	9	rarokar	rarokar	PROPN
cet-15446	109	10	,	,	PUNCT
cet-15446	109	11	n.	n.	NOUN
cet-15446	109	12	,	,	PUNCT
cet-15446	109	13	umekar	umekar	NOUN
cet-15446	109	14	,	,	PUNCT
cet-15446	109	15	m.	m.	NOUN
cet-15446	109	16	,	,	PUNCT
cet-15446	109	17	2024	2024	NUM
cet-15446	109	18	,	,	PUNCT
cet-15446	109	19	development	development	NOUN
cet-15446	109	20	and	and	CCONJ
cet-15446	109	21	assessment	assessment	NOUN
cet-15446	109	22	of	of	ADP
cet-15446	109	23	rutin	rutin	NOUN
cet-15446	109	24	loaded	load	VERB
cet-15446	109	25	transfersomes	transfersome	NOUN
cet-15446	109	26	to	to	PART
cet-15446	109	27	improve	improve	VERB
cet-15446	109	28	ex	ex	PRON
cet-15446	109	29	vivo	vivo	ADJ
cet-15446	109	30	membrane	membrane	NOUN
cet-15446	109	31	permeability	permeability	NOUN
cet-15446	109	32	and	and	CCONJ
cet-15446	109	33	in	in	ADP
cet-15446	109	34	vitro	vitro	X
cet-15446	109	35	efficacy	efficacy	NOUN
cet-15446	109	36	,	,	PUNCT
cet-15446	109	37	hybrid	hybrid	ADJ
cet-15446	109	38	advances	advance	NOUN
cet-15446	109	39	,	,	PUNCT
cet-15446	109	40	5	5	NUM
cet-15446	109	41	,	,	PUNCT
cet-15446	109	42	100144	100144	NUM
cet-15446	109	43	.	.	PUNCT
cet-15446	110	1	1176	1176	NUM
cet-15446	110	2	cet-vol117-b.pdf	cet-vol117-b.pdf	SYM
cet-15446	110	3	298sarnelli.pdf	298sarnelli.pdf	NUM
cet-15446	110	4	deformable	deformable	ADJ
cet-15446	110	5	nanovesicles	nanovesicle	NOUN
cet-15446	110	6	produced	produce	VERB
cet-15446	110	7	by	by	ADP
cet-15446	110	8	using	use	VERB
cet-15446	110	9	a	a	DET
cet-15446	110	10	supercritical	supercritical	ADJ
cet-15446	110	11	technology	technology	NOUN
cet-15446	110	12	for	for	ADP
cet-15446	110	13	enhanced	enhanced	ADJ
cet-15446	110	14	transdermal	transdermal	ADJ
cet-15446	110	15	drug	drug	NOUN
cet-15446	110	16	delivery	delivery	NOUN