id	sid	tid	token	lemma	pos
ctmj-188	1	1	ctmj	ctmj	NOUN
ctmj-188	1	2	|	|	ADV
ctmj-188	1	3	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	1	4	chinese	chinese	ADJ
ctmj-188	1	5	traditional	traditional	ADJ
ctmj-188	1	6	medicine	medicine	NOUN
ctmj-188	1	7	journal	journal	NOUN
ctmj-188	1	8	|	|	ADV
ctmj-188	1	9	2025	2025	NUM
ctmj-188	1	10	|	|	ADV
ctmj-188	1	11	vol	vol	NOUN
ctmj-188	1	12	8	8	NUM
ctmj-188	1	13	|issue	|issue	NOUN
ctmj-188	1	14	1	1	NUM
ctmj-188	1	15	44	44	NUM
ctmj-188	1	16	abstract	abstract	NOUN
ctmj-188	1	17	:	:	PUNCT
ctmj-188	1	18	our	our	PRON
ctmj-188	1	19	goal	goal	NOUN
ctmj-188	1	20	is	be	AUX
ctmj-188	1	21	to	to	PART
ctmj-188	1	22	learn	learn	VERB
ctmj-188	1	23	how	how	SCONJ
ctmj-188	1	24	qingjie	qingjie	NOUN
ctmj-188	1	25	fuzheng	fuzheng	PROPN
ctmj-188	1	26	granule	granule	PROPN
ctmj-188	1	27	(	(	PUNCT
ctmj-188	1	28	qfg	qfg	ADJ
ctmj-188	1	29	)	)	PUNCT
ctmj-188	1	30	and	and	CCONJ
ctmj-188	1	31	5	5	NUM
ctmj-188	1	32	-	-	PUNCT
ctmj-188	1	33	fluorouracil	fluorouracil	NOUN
ctmj-188	1	34	(	(	PUNCT
ctmj-188	1	35	5	5	NUM
ctmj-188	1	36	-	-	PUNCT
ctmj-188	1	37	fu	fu	NOUN
ctmj-188	1	38	)	)	PUNCT
ctmj-188	1	39	work	work	VERB
ctmj-188	1	40	together	together	ADV
ctmj-188	1	41	to	to	PART
ctmj-188	1	42	treat	treat	VERB
ctmj-188	1	43	colorectal	colorectal	ADJ
ctmj-188	1	44	cancer	cancer	NOUN
ctmj-188	1	45	.	.	PUNCT
ctmj-188	2	1	research	research	NOUN
ctmj-188	2	2	tools	tool	NOUN
ctmj-188	2	3	and	and	CCONJ
ctmj-188	2	4	procedures	procedure	NOUN
ctmj-188	2	5	:	:	PUNCT
ctmj-188	3	1	human	human	ADJ
ctmj-188	3	2	colorectal	colorectal	ADJ
ctmj-188	3	3	cells	cell	NOUN
ctmj-188	3	4	and	and	CCONJ
ctmj-188	3	5	xenograft	xenograft	NOUN
ctmj-188	3	6	mice	mouse	NOUN
ctmj-188	3	7	were	be	AUX
ctmj-188	3	8	utilized	utilize	VERB
ctmj-188	3	9	to	to	PART
ctmj-188	3	10	study	study	VERB
ctmj-188	3	11	the	the	DET
ctmj-188	3	12	synergistic	synergistic	ADJ
ctmj-188	3	13	anticancer	anticancer	NOUN
ctmj-188	3	14	capacity	capacity	NOUN
ctmj-188	3	15	of	of	ADP
ctmj-188	3	16	qfg	qfg	NOUN
ctmj-188	3	17	and	and	CCONJ
ctmj-188	3	18	5	5	NUM
ctmj-188	3	19	-	-	PUNCT
ctmj-188	3	20	fu	fu	NOUN
ctmj-188	3	21	,	,	PUNCT
ctmj-188	3	22	which	which	PRON
ctmj-188	3	23	targets	target	VERB
ctmj-188	3	24	the	the	DET
ctmj-188	3	25	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	3	26	3	3	NUM
ctmj-188	3	27	-	-	PUNCT
ctmj-188	3	28	kinase	kinase	NOUN
ctmj-188	3	29	/	/	SYM
ctmj-188	3	30	protein	protein	NOUN
ctmj-188	3	31	kinase	kinase	PROPN
ctmj-188	3	32	b	b	PROPN
ctmj-188	3	33	(	(	PUNCT
ctmj-188	3	34	pi3k	pi3k	PROPN
ctmj-188	3	35	/	/	SYM
ctmj-188	3	36	akt	akt	PROPN
ctmj-188	3	37	)	)	PUNCT
ctmj-188	3	38	signaling	signal	VERB
ctmj-188	3	39	pathway	pathway	NOUN
ctmj-188	3	40	.	.	PUNCT
ctmj-188	4	1	chou	chou	NOUN
ctmj-188	4	2	-	-	PUNCT
ctmj-188	4	3	talalay	talalay	NOUN
ctmj-188	4	4	was	be	AUX
ctmj-188	4	5	employed	employ	VERB
ctmj-188	4	6	to	to	PART
ctmj-188	4	7	generate	generate	VERB
ctmj-188	4	8	this	this	DET
ctmj-188	4	9	index	index	NOUN
ctmj-188	4	10	.	.	PUNCT
ctmj-188	5	1	findings	finding	NOUN
ctmj-188	5	2	:	:	PUNCT
ctmj-188	5	3	the	the	DET
ctmj-188	5	4	growth	growth	NOUN
ctmj-188	5	5	of	of	ADP
ctmj-188	5	6	hct-8	hct-8	PUNCT
ctmj-188	5	7	cells	cell	NOUN
ctmj-188	5	8	was	be	AUX
ctmj-188	5	9	suppressed	suppress	VERB
ctmj-188	5	10	by	by	ADP
ctmj-188	5	11	a	a	DET
ctmj-188	5	12	synergistic	synergistic	ADJ
ctmj-188	5	13	effect	effect	NOUN
ctmj-188	5	14	of	of	ADP
ctmj-188	5	15	qfg	qfg	NOUN
ctmj-188	5	16	and	and	CCONJ
ctmj-188	5	17	5	5	NUM
ctmj-188	5	18	-	-	PUNCT
ctmj-188	5	19	fu	fu	NOUN
ctmj-188	5	20	.	.	PUNCT
ctmj-188	6	1	the	the	DET
ctmj-188	6	2	combination	combination	NOUN
ctmj-188	6	3	of	of	ADP
ctmj-188	6	4	qfg	qfg	NOUN
ctmj-188	6	5	with	with	ADP
ctmj-188	6	6	5	5	NUM
ctmj-188	6	7	-	-	PUNCT
ctmj-188	6	8	fu	fu	NOUN
ctmj-188	6	9	in	in	ADP
ctmj-188	6	10	hct-8	hct-8	PUNCT
ctmj-188	6	11	cells	cell	NOUN
ctmj-188	6	12	and	and	CCONJ
ctmj-188	6	13	mice	mouse	NOUN
ctmj-188	6	14	resulted	result	VERB
ctmj-188	6	15	in	in	ADP
ctmj-188	6	16	apoptosis	apoptosis	NOUN
ctmj-188	6	17	induced	induce	VERB
ctmj-188	6	18	by	by	ADP
ctmj-188	6	19	regulation	regulation	NOUN
ctmj-188	6	20	of	of	ADP
ctmj-188	6	21	associated	associated	ADJ
ctmj-188	6	22	proteins	protein	NOUN
ctmj-188	6	23	,	,	PUNCT
ctmj-188	6	24	inhibition	inhibition	NOUN
ctmj-188	6	25	of	of	ADP
ctmj-188	6	26	proliferation	proliferation	NOUN
ctmj-188	6	27	,	,	PUNCT
ctmj-188	6	28	migration	migration	NOUN
ctmj-188	6	29	,	,	PUNCT
ctmj-188	6	30	and	and	CCONJ
ctmj-188	6	31	invasion	invasion	NOUN
ctmj-188	6	32	.	.	PUNCT
ctmj-188	7	1	in	in	ADP
ctmj-188	7	2	addition	addition	NOUN
ctmj-188	7	3	,	,	PUNCT
ctmj-188	7	4	enzymes	enzyme	NOUN
ctmj-188	7	5	involved	involve	VERB
ctmj-188	7	6	in	in	ADP
ctmj-188	7	7	5	5	NUM
ctmj-188	7	8	-	-	PUNCT
ctmj-188	7	9	fu	fu	NOUN
ctmj-188	7	10	metabolism	metabolism	NOUN
ctmj-188	7	11	,	,	PUNCT
ctmj-188	7	12	including	include	VERB
ctmj-188	7	13	thymidylate	thymidylate	NOUN
ctmj-188	7	14	synthase	synthase	NOUN
ctmj-188	7	15	and	and	CCONJ
ctmj-188	7	16	dihydropyrimidine	dihydropyrimidine	NOUN
ctmj-188	7	17	dehydrogenase	dehydrogenase	NOUN
ctmj-188	7	18	,	,	PUNCT
ctmj-188	7	19	were	be	AUX
ctmj-188	7	20	down	down	ADV
ctmj-188	7	21	-	-	PUNCT
ctmj-188	7	22	regulated	regulate	VERB
ctmj-188	7	23	by	by	ADP
ctmj-188	7	24	qfg	qfg	NOUN
ctmj-188	7	25	and	and	CCONJ
ctmj-188	7	26	5	5	NUM
ctmj-188	7	27	-	-	PUNCT
ctmj-188	7	28	fu	fu	NOUN
ctmj-188	7	29	.	.	PUNCT
ctmj-188	8	1	furthermore	furthermore	ADV
ctmj-188	8	2	,	,	PUNCT
ctmj-188	8	3	by	by	ADP
ctmj-188	8	4	inhibiting	inhibit	VERB
ctmj-188	8	5	the	the	DET
ctmj-188	8	6	pi3k	pi3k	PROPN
ctmj-188	8	7	/	/	SYM
ctmj-188	8	8	akt	akt	PROPN
ctmj-188	8	9	signaling	signal	VERB
ctmj-188	8	10	pathway	pathway	NOUN
ctmj-188	8	11	,	,	PUNCT
ctmj-188	8	12	it	it	PRON
ctmj-188	8	13	eased	ease	VERB
ctmj-188	8	14	cancer	cancer	NOUN
ctmj-188	8	15	-	-	PUNCT
ctmj-188	8	16	related	relate	VERB
ctmj-188	8	17	behaviors	behavior	NOUN
ctmj-188	8	18	such	such	ADJ
ctmj-188	8	19	as	as	ADP
ctmj-188	8	20	migration	migration	NOUN
ctmj-188	8	21	,	,	PUNCT
ctmj-188	8	22	invasion	invasion	NOUN
ctmj-188	8	23	,	,	PUNCT
ctmj-188	8	24	and	and	CCONJ
ctmj-188	8	25	proliferation	proliferation	NOUN
ctmj-188	8	26	.	.	PUNCT
ctmj-188	9	1	findings	finding	NOUN
ctmj-188	9	2	:	:	PUNCT
ctmj-188	9	3	by	by	ADP
ctmj-188	9	4	inhibiting	inhibit	VERB
ctmj-188	9	5	the	the	DET
ctmj-188	9	6	pi3k	pi3k	PROPN
ctmj-188	9	7	/	/	SYM
ctmj-188	9	8	akt	akt	PROPN
ctmj-188	9	9	signaling	signal	VERB
ctmj-188	9	10	pathway	pathway	NOUN
ctmj-188	9	11	,	,	PUNCT
ctmj-188	9	12	the	the	DET
ctmj-188	9	13	anti	anti	ADJ
ctmj-188	9	14	-	-	ADJ
ctmj-188	9	15	cancer	cancer	ADJ
ctmj-188	9	16	actions	action	NOUN
ctmj-188	9	17	of	of	ADP
ctmj-188	9	18	qfg	qfg	NOUN
ctmj-188	9	19	and	and	CCONJ
ctmj-188	9	20	5	5	NUM
ctmj-188	9	21	-	-	PUNCT
ctmj-188	9	22	fu	fu	NOUN
ctmj-188	9	23	are	be	AUX
ctmj-188	9	24	enhanced	enhance	VERB
ctmj-188	9	25	.	.	PUNCT
ctmj-188	10	1	keywords	keyword	NOUN
ctmj-188	10	2	:	:	PUNCT
ctmj-188	10	3	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	10	4	3	3	NUM
ctmj-188	10	5	-	-	PUNCT
ctmj-188	10	6	kinase	kinase	NOUN
ctmj-188	10	7	/	/	SYM
ctmj-188	10	8	protein	protein	NOUN
ctmj-188	10	9	kinase	kinase	PROPN
ctmj-188	10	10	b	b	PROPN
ctmj-188	10	11	signaling	signal	VERB
ctmj-188	10	12	pathway	pathway	NOUN
ctmj-188	10	13	,	,	PUNCT
ctmj-188	10	14	qingjie	qingjie	NOUN
ctmj-188	10	15	fuzheng	fuzheng	PROPN
ctmj-188	10	16	granule	granule	PROPN
ctmj-188	10	17	,	,	PUNCT
ctmj-188	10	18	5	5	NUM
ctmj-188	10	19	-	-	PUNCT
ctmj-188	10	20	fluorouracil	fluorouracil	NOUN
ctmj-188	10	21	,	,	PUNCT
ctmj-188	10	22	colorectal	colorectal	ADJ
ctmj-188	10	23	cancer	cancer	NOUN
ctmj-188	10	24	,	,	PUNCT
ctmj-188	10	25	synergistic	synergistic	ADJ
ctmj-188	10	26	impact	impact	NOUN
ctmj-188	10	27	chinese	chinese	ADJ
ctmj-188	10	28	traditional	traditional	ADJ
ctmj-188	10	29	medical	medical	ADJ
ctmj-188	10	30	journal	journal	PROPN
ctmj-188	10	31	qingjie	qingjie	PROPN
ctmj-188	10	32	fuzheng	fuzheng	PROPN
ctmj-188	10	33	granule	granule	PROPN
ctmj-188	10	34	and	and	CCONJ
ctmj-188	10	35	5	5	NUM
ctmj-188	10	36	-	-	PUNCT
ctmj-188	10	37	fluorouracil	fluorouracil	NOUN
ctmj-188	10	38	inhibit	inhibit	VERB
ctmj-188	10	39	colorectal	colorectal	ADJ
ctmj-188	10	40	cancer	cancer	NOUN
ctmj-188	10	41	growth	growth	NOUN
ctmj-188	10	42	in	in	ADP
ctmj-188	10	43	a	a	DET
ctmj-188	10	44	synergistic	synergistic	ADJ
ctmj-188	10	45	manner	manner	NOUN
ctmj-188	10	46	via	via	ADP
ctmj-188	10	47	the	the	DET
ctmj-188	10	48	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	10	49	3	3	NUM
ctmj-188	10	50	-	-	PUNCT
ctmj-188	10	51	kinase	kinase	NOUN
ctmj-188	10	52	/	/	SYM
ctmj-188	10	53	protein	protein	NOUN
ctmj-188	10	54	kinase	kinase	PROPN
ctmj-188	11	1	b	b	PROPN
ctmj-188	11	2	pathway	pathway	PROPN
ctmj-188	11	3	rajesh	rajesh	PROPN
ctmj-188	11	4	kumar	kumar	PROPN
ctmj-188	11	5	and	and	CCONJ
ctmj-188	11	6	ravi	ravi	PROPN
ctmj-188	11	7	prasad	prasad	PROPN
ctmj-188	11	8	1,2	1,2	NUM
ctmj-188	11	9	academy	academy	NOUN
ctmj-188	11	10	of	of	ADP
ctmj-188	11	11	acupuncture	acupuncture	NOUN
ctmj-188	11	12	and	and	CCONJ
ctmj-188	11	13	moxibustion	moxibustion	NOUN
ctmj-188	11	14	,	,	PUNCT
ctmj-188	11	15	fujian	fujian	PROPN
ctmj-188	11	16	university	university	PROPN
ctmj-188	11	17	of	of	ADP
ctmj-188	11	18	traditional	traditional	ADJ
ctmj-188	11	19	chinese	chinese	ADJ
ctmj-188	11	20	medicine	medicine	NOUN
ctmj-188	11	21	,	,	PUNCT
ctmj-188	11	22	fuzhou	fuzhou	PROPN
ctmj-188	11	23	,	,	PUNCT
ctmj-188	11	24	fujian	fujian	PROPN
ctmj-188	11	25	350122	350122	NUM
ctmj-188	11	26	,	,	PUNCT
ctmj-188	11	27	china	china	PROPN
ctmj-188	11	28	received	receive	VERB
ctmj-188	11	29	on	on	ADP
ctmj-188	11	30	:	:	PUNCT
ctmj-188	11	31	21	21	NUM
ctmj-188	11	32	oct	oct	PROPN
ctmj-188	11	33	2024	2024	NUM
ctmj-188	11	34	revised	revise	VERB
ctmj-188	11	35	on	on	ADP
ctmj-188	11	36	:	:	PUNCT
ctmj-188	11	37	20	20	NUM
ctmj-188	11	38	nov	nov	NOUN
ctmj-188	11	39	2024	2024	NUM
ctmj-188	11	40	accepted	accept	VERB
ctmj-188	11	41	date	date	NOUN
ctmj-188	11	42	:	:	PUNCT
ctmj-188	11	43	25	25	NUM
ctmj-188	11	44	dec	dec	PROPN
ctmj-188	11	45	2024	2024	NUM
ctmj-188	11	46	published	publish	VERB
ctmj-188	11	47	on	on	ADP
ctmj-188	11	48	:	:	PUNCT
ctmj-188	11	49	18	18	NUM
ctmj-188	11	50	jan	jan	PROPN
ctmj-188	11	51	2025	2025	NUM
ctmj-188	11	52	introduction	introduction	NOUN
ctmj-188	11	53	a	a	DET
ctmj-188	11	54	malignant	malignant	ADJ
ctmj-188	11	55	tumor	tumor	NOUN
ctmj-188	11	56	of	of	ADP
ctmj-188	11	57	the	the	DET
ctmj-188	11	58	gastrointestinal	gastrointestinal	ADJ
ctmj-188	11	59	tract	tract	NOUN
ctmj-188	11	60	,	,	PUNCT
ctmj-188	11	61	colorectal	colorectal	ADJ
ctmj-188	11	62	cancer	cancer	NOUN
ctmj-188	11	63	(	(	PUNCT
ctmj-188	11	64	crc	crc	NOUN
ctmj-188	11	65	)	)	PUNCT
ctmj-188	11	66	has	have	VERB
ctmj-188	11	67	a	a	DET
ctmj-188	11	68	high	high	ADJ
ctmj-188	11	69	incidence	incidence	NOUN
ctmj-188	11	70	rate	rate	NOUN
ctmj-188	11	71	and	and	CCONJ
ctmj-188	11	72	ranks	rank	VERB
ctmj-188	11	73	second	second	ADJ
ctmj-188	11	74	or	or	CCONJ
ctmj-188	11	75	third	third	ADJ
ctmj-188	11	76	in	in	ADP
ctmj-188	11	77	terms	term	NOUN
ctmj-188	11	78	of	of	ADP
ctmj-188	11	79	fatality	fatality	NOUN
ctmj-188	11	80	.	.	PUNCT
ctmj-188	12	1	[	[	X
ctmj-188	12	2	1	1	X
ctmj-188	12	3	]	]	PUNCT
ctmj-188	12	4	although	although	SCONJ
ctmj-188	12	5	surgery	surgery	NOUN
ctmj-188	12	6	is	be	AUX
ctmj-188	12	7	now	now	ADV
ctmj-188	12	8	the	the	DET
ctmj-188	12	9	gold	gold	ADJ
ctmj-188	12	10	standard	standard	NOUN
ctmj-188	12	11	for	for	ADP
ctmj-188	12	12	treating	treat	VERB
ctmj-188	12	13	crc	crc	NOUN
ctmj-188	12	14	,	,	PUNCT
ctmj-188	12	15	individuals	individual	NOUN
ctmj-188	12	16	who	who	PRON
ctmj-188	12	17	have	have	VERB
ctmj-188	12	18	postoperative	postoperative	ADJ
ctmj-188	12	19	recurrence	recurrence	NOUN
ctmj-188	12	20	,	,	PUNCT
ctmj-188	12	21	missed	miss	VERB
ctmj-188	12	22	surgical	surgical	ADJ
ctmj-188	12	23	opportunities	opportunity	NOUN
ctmj-188	12	24	,	,	PUNCT
ctmj-188	12	25	or	or	CCONJ
ctmj-188	12	26	metastatic	metastatic	ADJ
ctmj-188	12	27	disease	disease	NOUN
ctmj-188	12	28	still	still	ADV
ctmj-188	12	29	primarily	primarily	ADV
ctmj-188	12	30	get	get	VERB
ctmj-188	12	31	chemotherapy	chemotherapy	NOUN
ctmj-188	12	32	.	.	PUNCT
ctmj-188	13	1	(	(	PUNCT
ctmj-188	13	2	2	2	NUM
ctmj-188	13	3	,	,	PUNCT
ctmj-188	13	4	3	3	NUM
ctmj-188	13	5	)	)	PUNCT
ctmj-188	13	6	.	.	PUNCT
ctmj-188	14	1	one	one	NUM
ctmj-188	14	2	of	of	ADP
ctmj-188	14	3	the	the	DET
ctmj-188	14	4	most	most	ADV
ctmj-188	14	5	frequent	frequent	ADJ
ctmj-188	14	6	chemotherapy	chemotherapy	NOUN
ctmj-188	14	7	medications	medication	NOUN
ctmj-188	14	8	used	use	VERB
ctmj-188	14	9	to	to	PART
ctmj-188	14	10	treat	treat	VERB
ctmj-188	14	11	colorectal	colorectal	ADJ
ctmj-188	14	12	cancer	cancer	NOUN
ctmj-188	14	13	is	be	AUX
ctmj-188	14	14	5	5	NUM
ctmj-188	14	15	-	-	PUNCT
ctmj-188	14	16	fluorouracil	fluorouracil	NOUN
ctmj-188	14	17	(	(	PUNCT
ctmj-188	14	18	5	5	NUM
ctmj-188	14	19	-	-	PUNCT
ctmj-188	14	20	fu	fu	NOUN
ctmj-188	14	21	)	)	PUNCT
ctmj-188	14	22	.	.	PUNCT
ctmj-188	15	1	as	as	ADP
ctmj-188	15	2	a	a	DET
ctmj-188	15	3	chemotherapeutic	chemotherapeutic	ADJ
ctmj-188	15	4	treatment	treatment	NOUN
ctmj-188	15	5	that	that	PRON
ctmj-188	15	6	depends	depend	VERB
ctmj-188	15	7	on	on	ADP
ctmj-188	15	8	the	the	DET
ctmj-188	15	9	cell	cell	NOUN
ctmj-188	15	10	cycle	cycle	NOUN
ctmj-188	15	11	,	,	PUNCT
ctmj-188	15	12	5	5	NUM
ctmj-188	15	13	-	-	PUNCT
ctmj-188	15	14	fu	fu	NOUN
ctmj-188	15	15	prevents	prevent	VERB
ctmj-188	15	16	tumor	tumor	NOUN
ctmj-188	15	17	cell	cell	NOUN
ctmj-188	15	18	growth	growth	NOUN
ctmj-188	15	19	by	by	ADP
ctmj-188	15	20	interfering	interfere	VERB
ctmj-188	15	21	with	with	ADP
ctmj-188	15	22	dna	dna	PROPN
ctmj-188	15	23	synthesis	synthesis	NOUN
ctmj-188	15	24	,	,	PUNCT
ctmj-188	15	25	which	which	PRON
ctmj-188	15	26	in	in	ADP
ctmj-188	15	27	turn	turn	NOUN
ctmj-188	15	28	stops	stop	VERB
ctmj-188	15	29	cell	cell	NOUN
ctmj-188	15	30	cycles	cycle	NOUN
ctmj-188	15	31	.	.	PUNCT
ctmj-188	16	1	[	[	X
ctmj-188	16	2	5	5	NUM
ctmj-188	16	3	]	]	PUNCT
ctmj-188	16	4	although	although	SCONJ
ctmj-188	16	5	5fu	5fu	NOUN
ctmj-188	16	6	is	be	AUX
ctmj-188	16	7	very	very	ADV
ctmj-188	16	8	effective	effective	ADJ
ctmj-188	16	9	against	against	ADP
ctmj-188	16	10	cancer	cancer	NOUN
ctmj-188	16	11	,	,	PUNCT
ctmj-188	16	12	it	it	PRON
ctmj-188	16	13	has	have	AUX
ctmj-188	16	14	been	be	AUX
ctmj-188	16	15	used	use	VERB
ctmj-188	16	16	with	with	ADP
ctmj-188	16	17	caution	caution	NOUN
ctmj-188	16	18	due	due	ADP
ctmj-188	16	19	to	to	ADP
ctmj-188	16	20	its	its	PRON
ctmj-188	16	21	adverse	adverse	ADJ
ctmj-188	16	22	effects	effect	NOUN
ctmj-188	16	23	,	,	PUNCT
ctmj-188	16	24	which	which	PRON
ctmj-188	16	25	may	may	AUX
ctmj-188	16	26	harm	harm	VERB
ctmj-188	16	27	healthy	healthy	ADJ
ctmj-188	16	28	organisms	organism	NOUN
ctmj-188	16	29	and	and	CCONJ
ctmj-188	16	30	lower	low	ADJ
ctmj-188	16	31	patients	patient	NOUN
ctmj-188	16	32	'	'	PART
ctmj-188	16	33	quality	quality	NOUN
ctmj-188	16	34	of	of	ADP
ctmj-188	16	35	life	life	NOUN
ctmj-188	16	36	when	when	SCONJ
ctmj-188	16	37	taken	take	VERB
ctmj-188	16	38	in	in	ADP
ctmj-188	16	39	large	large	ADJ
ctmj-188	16	40	quantities	quantity	NOUN
ctmj-188	16	41	over	over	ADP
ctmj-188	16	42	an	an	DET
ctmj-188	16	43	extended	extended	ADJ
ctmj-188	16	44	length	length	NOUN
ctmj-188	16	45	of	of	ADP
ctmj-188	16	46	time	time	NOUN
ctmj-188	16	47	.	.	PUNCT
ctmj-188	17	1	in	in	ADP
ctmj-188	17	2	addition	addition	NOUN
ctmj-188	17	3	,	,	PUNCT
ctmj-188	17	4	therapeutic	therapeutic	ADJ
ctmj-188	17	5	efficacy	efficacy	NOUN
ctmj-188	17	6	is	be	AUX
ctmj-188	17	7	further	far	ADV
ctmj-188	17	8	diminished	diminish	VERB
ctmj-188	17	9	as	as	ADP
ctmj-188	17	10	a	a	DET
ctmj-188	17	11	result	result	NOUN
ctmj-188	17	12	of	of	ADP
ctmj-188	17	13	primary	primary	ADJ
ctmj-188	17	14	and	and	CCONJ
ctmj-188	17	15	secondary	secondary	ADJ
ctmj-188	17	16	chemotherapy	chemotherapy	NOUN
ctmj-188	17	17	resistance	resistance	NOUN
ctmj-188	17	18	.	.	PUNCT
ctmj-188	18	1	[	[	X
ctmj-188	18	2	6	6	NUM
ctmj-188	18	3	]	]	PUNCT
ctmj-188	18	4	therefore	therefore	ADV
ctmj-188	18	5	,	,	PUNCT
ctmj-188	18	6	there	there	PRON
ctmj-188	18	7	is	be	VERB
ctmj-188	18	8	an	an	DET
ctmj-188	18	9	immediate	immediate	ADJ
ctmj-188	18	10	need	need	NOUN
ctmj-188	18	11	to	to	PART
ctmj-188	18	12	develop	develop	VERB
ctmj-188	18	13	better	well	ADJ
ctmj-188	18	14	therapies	therapy	NOUN
ctmj-188	18	15	to	to	PART
ctmj-188	18	16	increase	increase	VERB
ctmj-188	18	17	the	the	DET
ctmj-188	18	18	effectiveness	effectiveness	NOUN
ctmj-188	18	19	of	of	ADP
ctmj-188	18	20	chemotherapy	chemotherapy	NOUN
ctmj-188	18	21	and	and	CCONJ
ctmj-188	18	22	enhance	enhance	VERB
ctmj-188	18	23	the	the	DET
ctmj-188	18	24	quality	quality	NOUN
ctmj-188	18	25	of	of	ADP
ctmj-188	18	26	life	life	NOUN
ctmj-188	18	27	for	for	ADP
ctmj-188	18	28	patients	patient	NOUN
ctmj-188	18	29	with	with	ADP
ctmj-188	18	30	colorectal	colorectal	ADJ
ctmj-188	18	31	cancer	cancer	NOUN
ctmj-188	18	32	.	.	PUNCT
ctmj-188	19	1	the	the	DET
ctmj-188	19	2	growth	growth	NOUN
ctmj-188	19	3	and	and	CCONJ
ctmj-188	19	4	chemoresistance	chemoresistance	NOUN
ctmj-188	19	5	of	of	ADP
ctmj-188	19	6	colorectal	colorectal	ADJ
ctmj-188	19	7	cancer	cancer	NOUN
ctmj-188	19	8	cells	cell	NOUN
ctmj-188	19	9	are	be	AUX
ctmj-188	19	10	regulated	regulate	VERB
ctmj-188	19	11	by	by	ADP
ctmj-188	19	12	the	the	DET
ctmj-188	19	13	phosphatidylinositol-3	phosphatidylinositol-3	PROPN
ctmj-188	19	14	-	-	PUNCT
ctmj-188	19	15	kinase	kinase	NOUN
ctmj-188	19	16	/	/	SYM
ctmj-188	19	17	protein	protein	NOUN
ctmj-188	19	18	kinase	kinase	PROPN
ctmj-188	19	19	b	b	PROPN
ctmj-188	19	20	(	(	PUNCT
ctmj-188	19	21	pi3k	pi3k	PROPN
ctmj-188	19	22	/	/	SYM
ctmj-188	19	23	akt	akt	PROPN
ctmj-188	19	24	)	)	PUNCT
ctmj-188	19	25	signaling	signal	VERB
ctmj-188	19	26	system	system	NOUN
ctmj-188	19	27	.	.	PUNCT
ctmj-188	20	1	[	[	X
ctmj-188	20	2	7	7	X
ctmj-188	20	3	]	]	PUNCT
ctmj-188	20	4	in	in	ADP
ctmj-188	20	5	a	a	DET
ctmj-188	20	6	typical	typical	ADJ
ctmj-188	20	7	scenario	scenario	NOUN
ctmj-188	20	8	,	,	PUNCT
ctmj-188	20	9	extracellular	extracellular	ADJ
ctmj-188	20	10	signals	signal	NOUN
ctmj-188	20	11	trigger	trigger	VERB
ctmj-188	20	12	pi3k	pi3k	NOUN
ctmj-188	20	13	activity	activity	NOUN
ctmj-188	20	14	,	,	PUNCT
ctmj-188	20	15	which	which	PRON
ctmj-188	20	16	in	in	ADP
ctmj-188	20	17	turn	turn	NOUN
ctmj-188	20	18	activates	activate	VERB
ctmj-188	20	19	akt	akt	PROPN
ctmj-188	20	20	.	.	PUNCT
ctmj-188	21	1	finally	finally	ADV
ctmj-188	21	2	,	,	PUNCT
ctmj-188	21	3	crc	crc	NOUN
ctmj-188	21	4	cell	cell	NOUN
ctmj-188	21	5	survival	survival	NOUN
ctmj-188	21	6	is	be	AUX
ctmj-188	21	7	enhanced	enhance	VERB
ctmj-188	21	8	by	by	ADP
ctmj-188	21	9	blocking	block	VERB
ctmj-188	21	10	apoptosis	apoptosis	NOUN
ctmj-188	21	11	via	via	ADP
ctmj-188	21	12	the	the	DET
ctmj-188	21	13	negative	negative	ADJ
ctmj-188	21	14	regulation	regulation	NOUN
ctmj-188	21	15	of	of	ADP
ctmj-188	21	16	b	b	NOUN
ctmj-188	21	17	-	-	PUNCT
ctmj-188	21	18	cell	cell	NOUN
ctmj-188	21	19	lymphoma-2	lymphoma-2	NOUN
ctmj-188	21	20	-	-	ADJ
ctmj-188	21	21	associated	associated	ADJ
ctmj-188	21	22	x	x	ADJ
ctmj-188	21	23	protein	protein	NOUN
ctmj-188	21	24	(	(	PUNCT
ctmj-188	21	25	bax	bax	NOUN
ctmj-188	21	26	)	)	PUNCT
ctmj-188	21	27	by	by	ADP
ctmj-188	21	28	activated	activate	VERB
ctmj-188	21	29	akt	akt	PROPN
ctmj-188	21	30	.	.	PUNCT
ctmj-188	22	1	[	[	X
ctmj-188	22	2	8	8	NUM
ctmj-188	22	3	]	]	PUNCT
ctmj-188	22	4	at	at	ADP
ctmj-188	22	5	the	the	DET
ctmj-188	22	6	same	same	ADJ
ctmj-188	22	7	time	time	NOUN
ctmj-188	22	8	,	,	PUNCT
ctmj-188	22	9	akt	akt	PROPN
ctmj-188	22	10	activation	activation	NOUN
ctmj-188	22	11	triggers	trigger	VERB
ctmj-188	22	12	emt	emt	PROPN
ctmj-188	22	13	,	,	PUNCT
ctmj-188	22	14	which	which	PRON
ctmj-188	22	15	improves	improve	VERB
ctmj-188	22	16	crc	crc	NOUN
ctmj-188	22	17	cell	cell	NOUN
ctmj-188	22	18	migration	migration	NOUN
ctmj-188	22	19	and	and	CCONJ
ctmj-188	22	20	invasion	invasion	NOUN
ctmj-188	22	21	and	and	CCONJ
ctmj-188	22	22	makes	make	VERB
ctmj-188	22	23	tumor	tumor	NOUN
ctmj-188	22	24	spread	spread	VERB
ctmj-188	22	25	easier	easy	ADJ
ctmj-188	22	26	.	.	PUNCT
ctmj-188	23	1	[	[	X
ctmj-188	23	2	9	9	NUM
ctmj-188	23	3	]	]	PUNCT
ctmj-188	23	4	therefore	therefore	ADV
ctmj-188	23	5	,	,	PUNCT
ctmj-188	23	6	reducing	reduce	VERB
ctmj-188	23	7	pi3k	pi3k	NOUN
ctmj-188	23	8	/	/	SYM
ctmj-188	23	9	akt	akt	PROPN
ctmj-188	23	10	activity	activity	NOUN
ctmj-188	23	11	is	be	AUX
ctmj-188	23	12	helpful	helpful	ADJ
ctmj-188	23	13	for	for	ADP
ctmj-188	23	14	many	many	ADJ
ctmj-188	23	15	reasons	reason	NOUN
ctmj-188	23	16	,	,	PUNCT
ctmj-188	23	17	including	include	VERB
ctmj-188	23	18	making	make	VERB
ctmj-188	23	19	crc	crc	NOUN
ctmj-188	23	20	cells	cell	NOUN
ctmj-188	23	21	more	more	ADV
ctmj-188	23	22	sensitive	sensitive	ADJ
ctmj-188	23	23	to	to	ADP
ctmj-188	23	24	chemotherapy	chemotherapy	VERB
ctmj-188	23	25	,	,	PUNCT
ctmj-188	23	26	reducing	reduce	VERB
ctmj-188	23	27	their	their	PRON
ctmj-188	23	28	ability	ability	NOUN
ctmj-188	23	29	to	to	PART
ctmj-188	23	30	proliferate	proliferate	VERB
ctmj-188	23	31	and	and	CCONJ
ctmj-188	23	32	metastasize	metastasize	VERB
ctmj-188	23	33	,	,	PUNCT
ctmj-188	23	34	and	and	CCONJ
ctmj-188	23	35	triggering	trigger	VERB
ctmj-188	23	36	cell	cell	NOUN
ctmj-188	23	37	death	death	NOUN
ctmj-188	23	38	.	.	PUNCT
ctmj-188	24	1	[	[	X
ctmj-188	24	2	10	10	NUM
ctmj-188	24	3	]	]	SYM
ctmj-188	24	4	45	45	NUM
ctmj-188	24	5	ctmj	ctmj	NOUN
ctmj-188	24	6	|	|	ADV
ctmj-188	24	7	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	24	8	chinese	chinese	ADJ
ctmj-188	24	9	traditional	traditional	ADJ
ctmj-188	24	10	medicine	medicine	NOUN
ctmj-188	24	11	journal	journal	NOUN
ctmj-188	24	12	|	|	ADV
ctmj-188	24	13	2025	2025	NUM
ctmj-188	24	14	|	|	ADV
ctmj-188	24	15	vol	vol	NOUN
ctmj-188	24	16	8	8	NUM
ctmj-188	24	17	|issue	|issue	NOUN
ctmj-188	24	18	1	1	NUM
ctmj-188	24	19	45	45	NUM
ctmj-188	24	20	utilizing	utilize	VERB
ctmj-188	24	21	two	two	NUM
ctmj-188	24	22	or	or	CCONJ
ctmj-188	24	23	more	more	ADJ
ctmj-188	24	24	medications	medication	NOUN
ctmj-188	24	25	in	in	ADP
ctmj-188	24	26	conjunction	conjunction	NOUN
ctmj-188	24	27	with	with	ADP
ctmj-188	24	28	one	one	NUM
ctmj-188	24	29	another	another	DET
ctmj-188	24	30	or	or	CCONJ
ctmj-188	24	31	in	in	ADP
ctmj-188	24	32	a	a	DET
ctmj-188	24	33	certain	certain	ADJ
ctmj-188	24	34	order	order	NOUN
ctmj-188	24	35	to	to	PART
ctmj-188	24	36	accomplish	accomplish	VERB
ctmj-188	24	37	therapeutic	therapeutic	ADJ
ctmj-188	24	38	objectives	objective	NOUN
ctmj-188	24	39	is	be	AUX
ctmj-188	24	40	known	know	VERB
ctmj-188	24	41	as	as	ADP
ctmj-188	24	42	combination	combination	NOUN
ctmj-188	24	43	therapy	therapy	NOUN
ctmj-188	24	44	,	,	PUNCT
ctmj-188	24	45	and	and	CCONJ
ctmj-188	24	46	it	it	PRON
ctmj-188	24	47	is	be	AUX
ctmj-188	24	48	a	a	DET
ctmj-188	24	49	commonly	commonly	ADV
ctmj-188	24	50	used	use	VERB
ctmj-188	24	51	method	method	NOUN
ctmj-188	24	52	in	in	ADP
ctmj-188	24	53	the	the	DET
ctmj-188	24	54	treatment	treatment	NOUN
ctmj-188	24	55	of	of	ADP
ctmj-188	24	56	many	many	ADJ
ctmj-188	24	57	disorders	disorder	NOUN
ctmj-188	24	58	.	.	PUNCT
ctmj-188	25	1	the	the	DET
ctmj-188	25	2	eleventh	eleventh	ADJ
ctmj-188	25	3	this	this	DET
ctmj-188	25	4	approach	approach	NOUN
ctmj-188	25	5	not	not	PART
ctmj-188	25	6	only	only	ADV
ctmj-188	25	7	improves	improve	VERB
ctmj-188	25	8	results	result	NOUN
ctmj-188	25	9	by	by	ADP
ctmj-188	25	10	making	make	VERB
ctmj-188	25	11	the	the	DET
ctmj-188	25	12	treatments	treatment	NOUN
ctmj-188	25	13	more	more	ADV
ctmj-188	25	14	effective	effective	ADJ
ctmj-188	25	15	,	,	PUNCT
ctmj-188	25	16	but	but	CCONJ
ctmj-188	25	17	it	it	PRON
ctmj-188	25	18	also	also	ADV
ctmj-188	25	19	lessens	lessen	VERB
ctmj-188	25	20	their	their	PRON
ctmj-188	25	21	side	side	NOUN
ctmj-188	25	22	effects	effect	NOUN
ctmj-188	25	23	and	and	CCONJ
ctmj-188	25	24	slows	slow	VERB
ctmj-188	25	25	the	the	DET
ctmj-188	25	26	development	development	NOUN
ctmj-188	25	27	of	of	ADP
ctmj-188	25	28	drug	drug	NOUN
ctmj-188	25	29	resistance	resistance	NOUN
ctmj-188	25	30	.	.	PUNCT
ctmj-188	26	1	a	a	DET
ctmj-188	26	2	synergistic	synergistic	ADJ
ctmj-188	26	3	effect	effect	NOUN
ctmj-188	26	4	occurs	occur	VERB
ctmj-188	26	5	when	when	SCONJ
ctmj-188	26	6	the	the	DET
ctmj-188	26	7	effects	effect	NOUN
ctmj-188	26	8	of	of	ADP
ctmj-188	26	9	several	several	ADJ
ctmj-188	26	10	medications	medication	NOUN
ctmj-188	26	11	work	work	VERB
ctmj-188	26	12	together	together	ADV
ctmj-188	26	13	.	.	PUNCT
ctmj-188	27	1	one	one	NUM
ctmj-188	27	2	way	way	NOUN
ctmj-188	27	3	to	to	PART
ctmj-188	27	4	classify	classify	VERB
ctmj-188	27	5	a	a	DET
ctmj-188	27	6	synergistic	synergistic	ADJ
ctmj-188	27	7	impact	impact	NOUN
ctmj-188	27	8	is	be	AUX
ctmj-188	27	9	by	by	ADP
ctmj-188	27	10	its	its	PRON
ctmj-188	27	11	strength	strength	NOUN
ctmj-188	27	12	;	;	PUNCT
ctmj-188	27	13	there	there	PRON
ctmj-188	27	14	are	be	VERB
ctmj-188	27	15	two	two	NUM
ctmj-188	27	16	main	main	ADJ
ctmj-188	27	17	types	type	NOUN
ctmj-188	27	18	:	:	PUNCT
ctmj-188	27	19	additive	additive	NOUN
ctmj-188	27	20	and	and	CCONJ
ctmj-188	27	21	reinforcing	reinforcing	NOUN
ctmj-188	27	22	.	.	PUNCT
ctmj-188	28	1	the	the	DET
ctmj-188	28	2	combined	combine	VERB
ctmj-188	28	3	impact	impact	NOUN
ctmj-188	28	4	of	of	ADP
ctmj-188	28	5	the	the	DET
ctmj-188	28	6	two	two	NUM
ctmj-188	28	7	medications	medication	NOUN
ctmj-188	28	8	is	be	AUX
ctmj-188	28	9	what	what	PRON
ctmj-188	28	10	is	be	AUX
ctmj-188	28	11	meant	mean	VERB
ctmj-188	28	12	by	by	ADP
ctmj-188	28	13	an	an	DET
ctmj-188	28	14	additive	additive	ADJ
ctmj-188	28	15	effect	effect	NOUN
ctmj-188	28	16	.	.	PUNCT
ctmj-188	29	1	to	to	PART
ctmj-188	29	2	have	have	VERB
ctmj-188	29	3	an	an	DET
ctmj-188	29	4	augmentation	augmentation	NOUN
ctmj-188	29	5	effect	effect	NOUN
ctmj-188	29	6	,	,	PUNCT
ctmj-188	29	7	all	all	PRON
ctmj-188	29	8	of	of	ADP
ctmj-188	29	9	the	the	DET
ctmj-188	29	10	parts	part	NOUN
ctmj-188	29	11	working	work	VERB
ctmj-188	29	12	together	together	ADV
ctmj-188	29	13	have	have	VERB
ctmj-188	29	14	a	a	DET
ctmj-188	29	15	stronger	strong	ADJ
ctmj-188	29	16	impact	impact	NOUN
ctmj-188	29	17	than	than	ADP
ctmj-188	29	18	each	each	DET
ctmj-188	29	19	one	one	NOUN
ctmj-188	29	20	working	work	VERB
ctmj-188	29	21	alone	alone	ADV
ctmj-188	29	22	.	.	PUNCT
ctmj-188	30	1	drug	drug	NOUN
ctmj-188	30	2	combinations	combination	NOUN
ctmj-188	30	3	may	may	AUX
ctmj-188	30	4	be	be	AUX
ctmj-188	30	5	quantitatively	quantitatively	ADV
ctmj-188	30	6	defined	define	VERB
ctmj-188	30	7	by	by	ADP
ctmj-188	30	8	choutalalay	choutalalay	NOUN
ctmj-188	30	9	's	's	PART
ctmj-188	30	10	combination	combination	NOUN
ctmj-188	30	11	index	index	NOUN
ctmj-188	30	12	(	(	PUNCT
ctmj-188	30	13	ci	ci	NOUN
ctmj-188	30	14	)	)	PUNCT
ctmj-188	30	15	,	,	PUNCT
ctmj-188	30	16	which	which	PRON
ctmj-188	30	17	measures	measure	VERB
ctmj-188	30	18	the	the	DET
ctmj-188	30	19	additive	additive	NOUN
ctmj-188	30	20	(	(	PUNCT
ctmj-188	30	21	ci	ci	NOUN
ctmj-188	30	22	=	=	SYM
ctmj-188	30	23	1	1	NUM
ctmj-188	30	24	)	)	PUNCT
ctmj-188	30	25	,	,	PUNCT
ctmj-188	30	26	synergistic	synergistic	ADJ
ctmj-188	30	27	(	(	PUNCT
ctmj-188	30	28	ci	ci	NOUN
ctmj-188	30	29	<	<	X
ctmj-188	30	30	1	1	NUM
ctmj-188	30	31	)	)	PUNCT
ctmj-188	30	32	,	,	PUNCT
ctmj-188	30	33	and	and	CCONJ
ctmj-188	30	34	antagonistic	antagonistic	ADJ
ctmj-188	30	35	(	(	PUNCT
ctmj-188	30	36	ci	ci	NOUN
ctmj-188	30	37	>	>	X
ctmj-188	30	38	1	1	NUM
ctmj-188	30	39	)	)	PUNCT
ctmj-188	30	40	effects	effect	NOUN
ctmj-188	30	41	.	.	PUNCT
ctmj-188	31	1	[	[	X
ctmj-188	31	2	12	12	NUM
ctmj-188	31	3	]	]	X
ctmj-188	31	4	finding	find	VERB
ctmj-188	31	5	effective	effective	ADJ
ctmj-188	31	6	chemoprotectors	chemoprotector	NOUN
ctmj-188	31	7	and	and	CCONJ
ctmj-188	31	8	potentiators	potentiator	NOUN
ctmj-188	31	9	,	,	PUNCT
ctmj-188	31	10	decreasing	decrease	VERB
ctmj-188	31	11	chemo	chemo	NOUN
ctmj-188	31	12	toxicities	toxicity	NOUN
ctmj-188	31	13	,	,	PUNCT
ctmj-188	31	14	and	and	CCONJ
ctmj-188	31	15	increasing	increase	VERB
ctmj-188	31	16	chemotherapy	chemotherapy	NOUN
ctmj-188	31	17	sensitivity	sensitivity	NOUN
ctmj-188	31	18	are	be	AUX
ctmj-188	31	19	all	all	PRON
ctmj-188	31	20	critical	critical	ADJ
ctmj-188	31	21	issues	issue	NOUN
ctmj-188	31	22	that	that	PRON
ctmj-188	31	23	must	must	AUX
ctmj-188	31	24	be	be	AUX
ctmj-188	31	25	addressed	address	VERB
ctmj-188	31	26	immediately	immediately	ADV
ctmj-188	31	27	.	.	PUNCT
ctmj-188	32	1	the	the	DET
ctmj-188	32	2	chinese	chinese	ADJ
ctmj-188	32	3	herbal	herbal	ADJ
ctmj-188	32	4	remedy	remedy	NOUN
ctmj-188	32	5	qingjie	qingjie	PROPN
ctmj-188	32	6	fuzheng	fuzheng	PROPN
ctmj-188	32	7	granules	granule	NOUN
ctmj-188	32	8	(	(	PUNCT
ctmj-188	32	9	qfg	qfg	NOUN
ctmj-188	32	10	)	)	PUNCT
ctmj-188	32	11	contains	contain	VERB
ctmj-188	32	12	roasted	roasted	ADJ
ctmj-188	32	13	malt	malt	NOUN
ctmj-188	32	14	,	,	PUNCT
ctmj-188	32	15	astragalus	astragalus	NOUN
ctmj-188	32	16	membranaceus	membranaceus	NOUN
ctmj-188	32	17	,	,	PUNCT
ctmj-188	32	18	hedyotis	hedyotis	ADJ
ctmj-188	32	19	diffusa	diffusa	NOUN
ctmj-188	32	20	,	,	PUNCT
ctmj-188	32	21	and	and	CCONJ
ctmj-188	32	22	scutellaria	scutellaria	NOUN
ctmj-188	32	23	barbata	barbata	NOUN
ctmj-188	32	24	.	.	PUNCT
ctmj-188	33	1	some	some	PRON
ctmj-188	33	2	of	of	ADP
ctmj-188	33	3	the	the	DET
ctmj-188	33	4	qualities	quality	NOUN
ctmj-188	33	5	possessed	possess	VERB
ctmj-188	33	6	by	by	ADP
ctmj-188	33	7	these	these	DET
ctmj-188	33	8	herbs	herb	NOUN
ctmj-188	33	9	include	include	VERB
ctmj-188	33	10	the	the	DET
ctmj-188	33	11	ability	ability	NOUN
ctmj-188	33	12	to	to	PART
ctmj-188	33	13	remove	remove	VERB
ctmj-188	33	14	heat	heat	NOUN
ctmj-188	33	15	,	,	PUNCT
ctmj-188	33	16	eliminate	eliminate	VERB
ctmj-188	33	17	toxins	toxin	NOUN
ctmj-188	33	18	,	,	PUNCT
ctmj-188	33	19	boost	boost	VERB
ctmj-188	33	20	vitality	vitality	NOUN
ctmj-188	33	21	,	,	PUNCT
ctmj-188	33	22	and	and	CCONJ
ctmj-188	33	23	eliminate	eliminate	VERB
ctmj-188	33	24	food	food	NOUN
ctmj-188	33	25	.	.	PUNCT
ctmj-188	34	1	inducing	induce	VERB
ctmj-188	34	2	apoptosis	apoptosis	NOUN
ctmj-188	34	3	and	and	CCONJ
ctmj-188	34	4	reducing	reduce	VERB
ctmj-188	34	5	proliferation	proliferation	NOUN
ctmj-188	34	6	via	via	ADP
ctmj-188	34	7	the	the	DET
ctmj-188	34	8	pi3k	pi3k	PROPN
ctmj-188	34	9	/	/	SYM
ctmj-188	34	10	akt	akt	PROPN
ctmj-188	34	11	signaling	signal	VERB
ctmj-188	34	12	pathway	pathway	NOUN
ctmj-188	34	13	,	,	PUNCT
ctmj-188	34	14	prior	prior	ADJ
ctmj-188	34	15	research	research	NOUN
ctmj-188	34	16	has	have	AUX
ctmj-188	34	17	shown	show	VERB
ctmj-188	34	18	that	that	SCONJ
ctmj-188	34	19	qfg	qfg	NOUN
ctmj-188	34	20	has	have	VERB
ctmj-188	34	21	an	an	DET
ctmj-188	34	22	anti	anti	ADJ
ctmj-188	34	23	-	-	ADJ
ctmj-188	34	24	cancer	cancer	ADJ
ctmj-188	34	25	effect	effect	NOUN
ctmj-188	34	26	on	on	ADP
ctmj-188	34	27	crc	crc	NOUN
ctmj-188	34	28	cells	cell	NOUN
ctmj-188	34	29	.	.	PUNCT
ctmj-188	35	1	in	in	ADP
ctmj-188	35	2	the	the	DET
ctmj-188	35	3	treatment	treatment	NOUN
ctmj-188	35	4	of	of	ADP
ctmj-188	35	5	colorectal	colorectal	ADJ
ctmj-188	35	6	cancer	cancer	NOUN
ctmj-188	35	7	,	,	PUNCT
ctmj-188	35	8	clinical	clinical	ADJ
ctmj-188	35	9	findings	finding	NOUN
ctmj-188	35	10	have	have	AUX
ctmj-188	35	11	shown	show	VERB
ctmj-188	35	12	that	that	SCONJ
ctmj-188	35	13	the	the	DET
ctmj-188	35	14	chemotherapeutic	chemotherapeutic	ADJ
ctmj-188	35	15	effectiveness	effectiveness	NOUN
ctmj-188	35	16	is	be	AUX
ctmj-188	35	17	enhanced	enhance	VERB
ctmj-188	35	18	when	when	SCONJ
ctmj-188	35	19	5	5	NUM
ctmj-188	35	20	-	-	PUNCT
ctmj-188	35	21	fu	fu	NOUN
ctmj-188	35	22	-	-	PUNCT
ctmj-188	35	23	based	base	VERB
ctmj-188	35	24	chemotherapy	chemotherapy	NOUN
ctmj-188	35	25	regimens	regimen	NOUN
ctmj-188	35	26	are	be	AUX
ctmj-188	35	27	coupled	couple	VERB
ctmj-188	35	28	with	with	ADP
ctmj-188	35	29	qfg	qfg	PROPN
ctmj-188	35	30	.	.	PUNCT
ctmj-188	36	1	references	reference	NOUN
ctmj-188	37	1	[	[	X
ctmj-188	37	2	13,14	13,14	NUM
ctmj-188	37	3	]	]	X
ctmj-188	37	4	:	:	PUNCT
ctmj-188	37	5	nevertheless	nevertheless	ADV
ctmj-188	37	6	,	,	PUNCT
ctmj-188	37	7	the	the	DET
ctmj-188	37	8	mechanism	mechanism	NOUN
ctmj-188	37	9	of	of	ADP
ctmj-188	37	10	5	5	NUM
ctmj-188	37	11	-	-	PUNCT
ctmj-188	37	12	fu	fu	NOUN
ctmj-188	37	13	coupled	couple	VERB
ctmj-188	37	14	with	with	ADP
ctmj-188	37	15	qfg	qfg	NOUN
ctmj-188	37	16	in	in	ADP
ctmj-188	37	17	crc	crc	NOUN
ctmj-188	37	18	is	be	AUX
ctmj-188	37	19	not	not	PART
ctmj-188	37	20	yet	yet	ADV
ctmj-188	37	21	the	the	DET
ctmj-188	37	22	subject	subject	NOUN
ctmj-188	37	23	of	of	ADP
ctmj-188	37	24	any	any	DET
ctmj-188	37	25	investigation	investigation	NOUN
ctmj-188	37	26	.	.	PUNCT
ctmj-188	38	1	this	this	DET
ctmj-188	38	2	study	study	NOUN
ctmj-188	38	3	's	's	PART
ctmj-188	38	4	overarching	overarching	ADJ
ctmj-188	38	5	goal	goal	NOUN
ctmj-188	38	6	is	be	AUX
ctmj-188	38	7	to	to	PART
ctmj-188	38	8	learn	learn	VERB
ctmj-188	38	9	more	more	ADJ
ctmj-188	38	10	about	about	ADP
ctmj-188	38	11	the	the	DET
ctmj-188	38	12	possible	possible	ADJ
ctmj-188	38	13	mechanism	mechanism	NOUN
ctmj-188	38	14	of	of	ADP
ctmj-188	38	15	action	action	NOUN
ctmj-188	38	16	of	of	ADP
ctmj-188	38	17	5	5	NUM
ctmj-188	38	18	-	-	PUNCT
ctmj-188	38	19	fu	fu	NOUN
ctmj-188	38	20	with	with	ADP
ctmj-188	38	21	qfg	qfg	NOUN
ctmj-188	38	22	in	in	ADP
ctmj-188	38	23	crc	crc	NOUN
ctmj-188	38	24	and	and	CCONJ
ctmj-188	38	25	their	their	PRON
ctmj-188	38	26	synergistic	synergistic	ADJ
ctmj-188	38	27	anti	anti	ADJ
ctmj-188	38	28	-	-	ADJ
ctmj-188	38	29	tumor	tumor	ADJ
ctmj-188	38	30	impact	impact	NOUN
ctmj-188	38	31	.	.	PUNCT
ctmj-188	39	1	materials	material	NOUN
ctmj-188	39	2	and	and	CCONJ
ctmj-188	39	3	methods	method	NOUN
ctmj-188	39	4	roswell	roswell	PROPN
ctmj-188	39	5	park	park	PROPN
ctmj-188	39	6	memorial	memorial	PROPN
ctmj-188	39	7	institute	institute	PROPN
ctmj-188	39	8	(	(	PUNCT
ctmj-188	39	9	rpmi	rpmi	NOUN
ctmj-188	39	10	)	)	PUNCT
ctmj-188	39	11	1640	1640	NUM
ctmj-188	39	12	medium	medium	NOUN
ctmj-188	39	13	(	(	PUNCT
ctmj-188	39	14	c11875500bt	c11875500bt	NOUN
ctmj-188	39	15	)	)	PUNCT
ctmj-188	39	16	,	,	PUNCT
ctmj-188	39	17	fetal	fetal	ADJ
ctmj-188	39	18	bovine	bovine	NOUN
ctmj-188	39	19	serum	serum	NOUN
ctmj-188	39	20	(	(	PUNCT
ctmj-188	39	21	fbs	fbs	PROPN
ctmj-188	39	22	)	)	PUNCT
ctmj-188	39	23	(	(	PUNCT
ctmj-188	39	24	10099141	10099141	NUM
ctmj-188	39	25	)	)	PUNCT
ctmj-188	39	26	,	,	PUNCT
ctmj-188	39	27	penicillin	penicillin	NOUN
ctmj-188	39	28	and	and	CCONJ
ctmj-188	39	29	streptomycin	streptomycin	PROPN
ctmj-188	39	30	(	(	PUNCT
ctmj-188	39	31	15140122	15140122	NUM
ctmj-188	39	32	)	)	PUNCT
ctmj-188	39	33	were	be	AUX
ctmj-188	39	34	obtained	obtain	VERB
ctmj-188	39	35	from	from	ADP
ctmj-188	39	36	life	life	NOUN
ctmj-188	39	37	technologies	technology	NOUN
ctmj-188	39	38	;	;	PUNCT
ctmj-188	39	39	crystalline	crystalline	ADJ
ctmj-188	39	40	violet	violet	NOUN
ctmj-188	39	41	(	(	PUNCT
ctmj-188	39	42	g1062	g1062	NOUN
ctmj-188	39	43	,	,	PUNCT
ctmj-188	39	44	solarbio	solarbio	NOUN
ctmj-188	39	45	)	)	PUNCT
ctmj-188	39	46	;	;	PUNCT
ctmj-188	39	47	cell	cell	NOUN
ctmj-188	39	48	counting	counting	NOUN
ctmj-188	39	49	kit	kit	NOUN
ctmj-188	39	50	8	8	NUM
ctmj-188	39	51	(	(	PUNCT
ctmj-188	39	52	cck8	cck8	PROPN
ctmj-188	39	53	)	)	PUNCT
ctmj-188	39	54	kit	kit	NOUN
ctmj-188	39	55	(	(	PUNCT
ctmj-188	39	56	kga3111018	kga3111018	NOUN
ctmj-188	39	57	)	)	PUNCT
ctmj-188	39	58	,	,	PUNCT
ctmj-188	39	59	annexin‑v	annexin‑v	PROPN
ctmj-188	39	60	fitc	fitc	PROPN
ctmj-188	39	61	/	/	SYM
ctmj-188	39	62	pi	pi	PROPN
ctmj-188	39	63	kit	kit	NOUN
ctmj-188	39	64	(	(	PUNCT
ctmj-188	39	65	kga108	kga108	PROPN
ctmj-188	39	66	)	)	PUNCT
ctmj-188	39	67	and	and	CCONJ
ctmj-188	39	68	terminal	terminal	PROPN
ctmj-188	39	69	deoxynucleotidyl	deoxynucleotidyl	NOUN
ctmj-188	39	70	transferase‑mediated	transferase‑mediate	VERB
ctmj-188	39	71	dutp‑biotin	dutp‑biotin	NUM
ctmj-188	39	72	nick‑end	nick‑end	PROPN
ctmj-188	39	73	labeling	labeling	NOUN
ctmj-188	39	74	(	(	PUNCT
ctmj-188	39	75	tunel	tunel	NOUN
ctmj-188	39	76	)	)	PUNCT
ctmj-188	39	77	kit	kit	NOUN
ctmj-188	39	78	(	(	PUNCT
ctmj-188	39	79	kga704	kga704	PROPN
ctmj-188	39	80	)	)	PUNCT
ctmj-188	39	81	were	be	AUX
ctmj-188	39	82	required	require	VERB
ctmj-188	39	83	from	from	ADP
ctmj-188	39	84	keygene	keygene	PROPN
ctmj-188	39	85	biotech	biotech	PROPN
ctmj-188	39	86	co.	co.	PROPN
ctmj-188	39	87	,	,	PUNCT
ctmj-188	39	88	ltd	ltd	PROPN
ctmj-188	39	89	.	.	PROPN
ctmj-188	39	90	(	(	PUNCT
ctmj-188	39	91	nanjing	nanjing	PROPN
ctmj-188	39	92	,	,	PUNCT
ctmj-188	39	93	china	china	PROPN
ctmj-188	39	94	)	)	PUNCT
ctmj-188	39	95	;	;	PUNCT
ctmj-188	39	96	transwell	transwell	NOUN
ctmj-188	39	97	chamber	chamber	NOUN
ctmj-188	39	98	(	(	PUNCT
ctmj-188	39	99	3422	3422	NUM
ctmj-188	39	100	,	,	PUNCT
ctmj-188	39	101	corning	corning	PROPN
ctmj-188	39	102	inc	inc	PROPN
ctmj-188	39	103	.	.	PROPN
ctmj-188	39	104	)	)	PUNCT
ctmj-188	39	105	;	;	PUNCT
ctmj-188	39	106	antibodies	antibodie	VERB
ctmj-188	39	107	to	to	ADP
ctmj-188	39	108	bax	bax	PROPN
ctmj-188	39	109	(	(	PUNCT
ctmj-188	39	110	50599	50599	NUM
ctmj-188	39	111	-	-	SYM
ctmj-188	39	112	2	2	NUM
ctmj-188	39	113	)	)	PUNCT
ctmj-188	39	114	,	,	PUNCT
ctmj-188	39	115	bcl‑2	bcl‑2	VERB
ctmj-188	39	116	(	(	PUNCT
ctmj-188	39	117	12789‑1	12789‑1	NUM
ctmj-188	39	118	)	)	PUNCT
ctmj-188	39	119	,	,	PUNCT
ctmj-188	39	120	cdk4	cdk4	NOUN
ctmj-188	39	121	(	(	PUNCT
ctmj-188	39	122	11026‑1‑ap	11026‑1‑ap	PROPN
ctmj-188	39	123	)	)	PUNCT
ctmj-188	39	124	,	,	PUNCT
ctmj-188	39	125	cyclin	cyclin	NOUN
ctmj-188	39	126	d1	d1	PROPN
ctmj-188	39	127	(	(	PUNCT
ctmj-188	39	128	60186	60186	NUM
ctmj-188	39	129	)	)	PUNCT
ctmj-188	39	130	,	,	PUNCT
ctmj-188	39	131	p21	p21	NOUN
ctmj-188	39	132	(	(	PUNCT
ctmj-188	39	133	10355‑1‑ap	10355‑1‑ap	NOUN
ctmj-188	39	134	)	)	PUNCT
ctmj-188	39	135	,	,	PUNCT
ctmj-188	39	136	vimentin	vimentin	X
ctmj-188	39	137	(	(	PUNCT
ctmj-188	39	138	10366‑1‑ap	10366‑1‑ap	PROPN
ctmj-188	39	139	)	)	PUNCT
ctmj-188	39	140	,	,	PUNCT
ctmj-188	39	141	pi3k	pi3k	X
ctmj-188	39	142	(	(	PUNCT
ctmj-188	39	143	60225‑1	60225‑1	NUM
ctmj-188	39	144	)	)	PUNCT
ctmj-188	39	145	,	,	PUNCT
ctmj-188	39	146	and	and	CCONJ
ctmj-188	39	147	gapdh	gapdh	NOUN
ctmj-188	39	148	(	(	PUNCT
ctmj-188	39	149	60004	60004	NUM
ctmj-188	39	150	)	)	PUNCT
ctmj-188	39	151	were	be	AUX
ctmj-188	39	152	purchased	purchase	VERB
ctmj-188	39	153	from	from	ADP
ctmj-188	39	154	proteintech	proteintech	NOUN
ctmj-188	39	155	(	(	PUNCT
ctmj-188	39	156	rosemount	rosemount	PROPN
ctmj-188	39	157	,	,	PUNCT
ctmj-188	39	158	il	il	PROPN
ctmj-188	39	159	,	,	PUNCT
ctmj-188	39	160	usa	usa	PROPN
ctmj-188	39	161	)	)	PUNCT
ctmj-188	39	162	.	.	PUNCT
ctmj-188	40	1	n‑cadherin	n‑cadherin	PROPN
ctmj-188	40	2	(	(	PUNCT
ctmj-188	40	3	14215s	14215s	NUM
ctmj-188	40	4	)	)	PUNCT
ctmj-188	40	5	,	,	PUNCT
ctmj-188	40	6	e‑cadherin	e‑cadherin	PROPN
ctmj-188	40	7	(	(	PUNCT
ctmj-188	40	8	14472s	14472s	NUM
ctmj-188	40	9	)	)	PUNCT
ctmj-188	40	10	,	,	PUNCT
ctmj-188	40	11	cleaved	cleaved	ADJ
ctmj-188	40	12	caspase‑3	caspase‑3	PROPN
ctmj-188	40	13	(	(	PUNCT
ctmj-188	40	14	9664	9664	NUM
ctmj-188	40	15	)	)	PUNCT
ctmj-188	40	16	,	,	PUNCT
ctmj-188	40	17	akt	akt	PROPN
ctmj-188	40	18	(	(	PUNCT
ctmj-188	40	19	4685s	4685s	NUM
ctmj-188	40	20	)	)	PUNCT
ctmj-188	40	21	,	,	PUNCT
ctmj-188	40	22	p‑akt	p‑akt	X
ctmj-188	40	23	(	(	PUNCT
ctmj-188	40	24	4060s	4060s	NUM
ctmj-188	40	25	)	)	PUNCT
ctmj-188	40	26	were	be	AUX
ctmj-188	40	27	purchased	purchase	VERB
ctmj-188	40	28	from	from	ADP
ctmj-188	40	29	cell	cell	NOUN
ctmj-188	40	30	signaling	signal	VERB
ctmj-188	40	31	technology	technology	NOUN
ctmj-188	40	32	,	,	PUNCT
ctmj-188	40	33	inc	inc	PROPN
ctmj-188	40	34	.	.	PROPN
ctmj-188	40	35	,	,	PUNCT
ctmj-188	40	36	(	(	PUNCT
ctmj-188	40	37	danvers	danver	NOUN
ctmj-188	40	38	,	,	PUNCT
ctmj-188	40	39	ma	ma	PROPN
ctmj-188	40	40	,	,	PUNCT
ctmj-188	40	41	usa	usa	PROPN
ctmj-188	40	42	)	)	PUNCT
ctmj-188	40	43	.	.	PUNCT
ctmj-188	41	1	the	the	DET
ctmj-188	41	2	enhanced	enhance	VERB
ctmj-188	41	3	chemiluminescent	chemiluminescent	NOUN
ctmj-188	41	4	substrate	substrate	NOUN
ctmj-188	41	5	for	for	ADP
ctmj-188	41	6	horseradish	horseradish	ADJ
ctmj-188	41	7	peroxidase	peroxidase	NOUN
ctmj-188	41	8	(	(	PUNCT
ctmj-188	41	9	hrp	hrp	NOUN
ctmj-188	41	10	)	)	PUNCT
ctmj-188	41	11	activity	activity	NOUN
ctmj-188	41	12	was	be	AUX
ctmj-188	41	13	acquired	acquire	VERB
ctmj-188	41	14	from	from	ADP
ctmj-188	41	15	us	we	PRON
ctmj-188	41	16	everbright	everbright	NOUN
ctmj-188	41	17	(	(	PUNCT
ctmj-188	41	18	s6009s	s6009s	PROPN
ctmj-188	41	19	,	,	PUNCT
ctmj-188	41	20	u.s	u.s	PROPN
ctmj-188	41	21	.	.	PROPN
ctmj-188	41	22	everbright	everbright	PROPN
ctmj-188	41	23	,	,	PUNCT
ctmj-188	41	24	china	china	PROPN
ctmj-188	41	25	)	)	PUNCT
ctmj-188	41	26	.	.	PUNCT
ctmj-188	42	1	other	other	ADJ
ctmj-188	42	2	reagents	reagent	NOUN
ctmj-188	42	3	,	,	PUNCT
ctmj-188	42	4	except	except	SCONJ
ctmj-188	42	5	for	for	ADP
ctmj-188	42	6	explicitly	explicitly	ADV
ctmj-188	42	7	mentioned	mention	VERB
ctmj-188	42	8	,	,	PUNCT
ctmj-188	42	9	were	be	AUX
ctmj-188	42	10	obtained	obtain	VERB
ctmj-188	42	11	from	from	ADP
ctmj-188	42	12	nest	nest	NOUN
ctmj-188	42	13	(	(	PUNCT
ctmj-188	42	14	wuxi	wuxi	PROPN
ctmj-188	42	15	,	,	PUNCT
ctmj-188	42	16	china	china	PROPN
ctmj-188	42	17	)	)	PUNCT
ctmj-188	42	18	.	.	PUNCT
ctmj-188	43	1	cell	cell	NOUN
ctmj-188	43	2	culture	culture	NOUN
ctmj-188	43	3	hct‑8	hct‑8	NOUN
ctmj-188	43	4	and	and	CCONJ
ctmj-188	43	5	hct‑116	hct‑116	NOUN
ctmj-188	43	6	cells	cell	NOUN
ctmj-188	43	7	were	be	AUX
ctmj-188	43	8	cultured	cultured	ADJ
ctmj-188	43	9	in	in	ADP
ctmj-188	43	10	rpmi	rpmi	NOUN
ctmj-188	43	11	1640	1640	NUM
ctmj-188	43	12	complete	complete	ADJ
ctmj-188	43	13	medium	medium	NOUN
ctmj-188	43	14	which	which	PRON
ctmj-188	43	15	contained	contain	VERB
ctmj-188	43	16	10	10	NUM
ctmj-188	43	17	%	%	NOUN
ctmj-188	43	18	fbs	fbs	PROPN
ctmj-188	43	19	,	,	PUNCT
ctmj-188	43	20	100	100	NUM
ctmj-188	43	21	u	u	NOUN
ctmj-188	43	22	/	/	SYM
ctmj-188	43	23	ml	ml	NOUN
ctmj-188	43	24	penicillin	penicillin	NOUN
ctmj-188	43	25	and	and	CCONJ
ctmj-188	43	26	100	100	NUM
ctmj-188	43	27	g	g	NOUN
ctmj-188	43	28	/	/	SYM
ctmj-188	43	29	ml	ml	NOUN
ctmj-188	43	30	streptomycin	streptomycin	PROPN
ctmj-188	43	31	.	.	PUNCT
ctmj-188	44	1	when	when	SCONJ
ctmj-188	44	2	the	the	DET
ctmj-188	44	3	cell	cell	NOUN
ctmj-188	44	4	confluence	confluence	NOUN
ctmj-188	44	5	reached	reach	VERB
ctmj-188	44	6	80%~90	80%~90	NUM
ctmj-188	44	7	%	%	NOUN
ctmj-188	44	8	and	and	CCONJ
ctmj-188	44	9	the	the	DET
ctmj-188	44	10	cells	cell	NOUN
ctmj-188	44	11	were	be	AUX
ctmj-188	44	12	subcultured	subculture	VERB
ctmj-188	44	13	.	.	PUNCT
ctmj-188	45	1	animals	animal	NOUN
ctmj-188	45	2	a	a	DET
ctmj-188	45	3	total	total	NOUN
ctmj-188	45	4	of	of	ADP
ctmj-188	45	5	40	40	NUM
ctmj-188	46	1	spf‑grade	spf‑grade	NOUN
ctmj-188	46	2	male	male	ADJ
ctmj-188	46	3	balb	balb	NOUN
ctmj-188	46	4	/	/	SYM
ctmj-188	46	5	c	c	NOUN
ctmj-188	46	6	nude	nude	ADJ
ctmj-188	46	7	mice	mouse	NOUN
ctmj-188	46	8	,	,	PUNCT
ctmj-188	46	9	acquired	acquire	VERB
ctmj-188	46	10	from	from	ADP
ctmj-188	46	11	slike	slike	PROPN
ctmj-188	46	12	co.	co.	PROPN
ctmj-188	46	13	ltd	ltd	PROPN
ctmj-188	46	14	.	.	PROPN
ctmj-188	46	15	,	,	PUNCT
ctmj-188	46	16	(	(	PUNCT
ctmj-188	46	17	shanghai	shanghai	PROPN
ctmj-188	46	18	,	,	PUNCT
ctmj-188	46	19	china	china	PROPN
ctmj-188	46	20	)	)	PUNCT
ctmj-188	46	21	,	,	PUNCT
ctmj-188	46	22	weighting	weight	VERB
ctmj-188	46	23	18–20	18–20	NUM
ctmj-188	46	24	g	g	NOUN
ctmj-188	46	25	,	,	PUNCT
ctmj-188	46	26	were	be	AUX
ctmj-188	46	27	kept	keep	VERB
ctmj-188	46	28	independently	independently	ADV
ctmj-188	46	29	ventilated	ventilate	VERB
ctmj-188	46	30	animal	animal	NOUN
ctmj-188	46	31	cage	cage	NOUN
ctmj-188	46	32	.	.	PUNCT
ctmj-188	47	1	the	the	DET
ctmj-188	47	2	mice	mouse	NOUN
ctmj-188	47	3	were	be	AUX
ctmj-188	47	4	allowed	allow	VERB
ctmj-188	47	5	to	to	PART
ctmj-188	47	6	eat	eat	VERB
ctmj-188	47	7	and	and	CCONJ
ctmj-188	47	8	drink	drink	VERB
ctmj-188	47	9	ad	ad	NOUN
ctmj-188	47	10	libitum	libitum	NOUN
ctmj-188	47	11	.	.	PUNCT
ctmj-188	48	1	all	all	DET
ctmj-188	48	2	experimental	experimental	ADJ
ctmj-188	48	3	procedures	procedure	NOUN
ctmj-188	48	4	were	be	AUX
ctmj-188	48	5	performed	perform	VERB
ctmj-188	48	6	in	in	ADP
ctmj-188	48	7	accordance	accordance	NOUN
ctmj-188	48	8	with	with	ADP
ctmj-188	48	9	the	the	DET
ctmj-188	48	10	guidelines	guideline	NOUN
ctmj-188	48	11	for	for	ADP
ctmj-188	48	12	animal	animal	NOUN
ctmj-188	48	13	experimentation	experimentation	NOUN
ctmj-188	48	14	of	of	ADP
ctmj-188	48	15	fujian	fujian	PROPN
ctmj-188	48	16	university	university	PROPN
ctmj-188	48	17	of	of	ADP
ctmj-188	48	18	traditional	traditional	ADJ
ctmj-188	48	19	chinese	chinese	ADJ
ctmj-188	48	20	medicine	medicine	NOUN
ctmj-188	48	21	and	and	CCONJ
ctmj-188	48	22	were	be	AUX
ctmj-188	48	23	approved	approve	VERB
ctmj-188	48	24	by	by	ADP
ctmj-188	48	25	the	the	DET
ctmj-188	48	26	fujian	fujian	PROPN
ctmj-188	48	27	institute	institute	PROPN
ctmj-188	48	28	of	of	ADP
ctmj-188	48	29	traditional	traditional	ADJ
ctmj-188	48	30	chinese	chinese	ADJ
ctmj-188	48	31	medicine	medicine	NOUN
ctmj-188	48	32	animal	animal	NOUN
ctmj-188	48	33	ethics	ethic	NOUN
ctmj-188	48	34	committee	committee	PROPN
ctmj-188	48	35	(	(	PUNCT
ctmj-188	48	36	fjtcm	fjtcm	NOUN
ctmj-188	48	37	iacuc	iacuc	NOUN
ctmj-188	48	38	2021018	2021018	NUM
ctmj-188	48	39	)	)	PUNCT
ctmj-188	48	40	.	.	PUNCT
ctmj-188	49	1	cell	cell	NOUN
ctmj-188	49	2	viability	viability	NOUN
ctmj-188	49	3	assay	assay	VERB
ctmj-188	49	4	hct-8	hct-8	PUNCT
ctmj-188	49	5	and	and	CCONJ
ctmj-188	49	6	hct-116	hct-116	INTJ
ctmj-188	49	7	cells	cell	NOUN
ctmj-188	49	8	were	be	AUX
ctmj-188	49	9	inoculated	inoculate	VERB
ctmj-188	49	10	in	in	ADP
ctmj-188	49	11	96	96	NUM
ctmj-188	49	12	-	-	PUNCT
ctmj-188	49	13	well	well	NOUN
ctmj-188	49	14	plates	plate	NOUN
ctmj-188	49	15	(	(	PUNCT
ctmj-188	49	16	100	100	NUM
ctmj-188	49	17	l	l	NOUN
ctmj-188	49	18	/	/	SYM
ctmj-188	49	19	well	well	NOUN
ctmj-188	49	20	)	)	PUNCT
ctmj-188	49	21	at	at	ADP
ctmj-188	49	22	a	a	DET
ctmj-188	49	23	density	density	NOUN
ctmj-188	49	24	of	of	ADP
ctmj-188	49	25	1.0	1.0	NUM
ctmj-188	49	26	×	×	NOUN
ctmj-188	49	27	105	105	NUM
ctmj-188	49	28	cells	cell	NOUN
ctmj-188	49	29	/	/	SYM
ctmj-188	49	30	ml	ml	NOUN
ctmj-188	49	31	,	,	PUNCT
ctmj-188	49	32	and	and	CCONJ
ctmj-188	49	33	there	there	PRON
ctmj-188	49	34	are	be	VERB
ctmj-188	49	35	6	6	NUM
ctmj-188	49	36	replicates	replicate	NOUN
ctmj-188	49	37	in	in	ADP
ctmj-188	49	38	each	each	DET
ctmj-188	49	39	group	group	NOUN
ctmj-188	49	40	.	.	PUNCT
ctmj-188	50	1	the	the	DET
ctmj-188	50	2	cells	cell	NOUN
ctmj-188	50	3	were	be	AUX
ctmj-188	50	4	cultured	cultured	ADJ
ctmj-188	50	5	overnight	overnight	ADV
ctmj-188	50	6	at	at	ADP
ctmj-188	50	7	37	37	NUM
ctmj-188	50	8	°	°	NOUN
ctmj-188	50	9	c	c	NOUN
ctmj-188	50	10	,	,	PUNCT
ctmj-188	50	11	5	5	NUM
ctmj-188	50	12	%	%	NOUN
ctmj-188	50	13	co2	co2	NOUN
ctmj-188	50	14	,	,	PUNCT
ctmj-188	50	15	and	and	CCONJ
ctmj-188	50	16	saturated	saturated	ADJ
ctmj-188	50	17	humidity	humidity	NOUN
ctmj-188	50	18	.	.	PUNCT
ctmj-188	51	1	afterward	afterward	ADV
ctmj-188	51	2	,	,	PUNCT
ctmj-188	51	3	treatment	treatment	NOUN
ctmj-188	51	4	with	with	ADP
ctmj-188	51	5	different	different	ADJ
ctmj-188	51	6	drugs	drug	NOUN
ctmj-188	51	7	for	for	ADP
ctmj-188	51	8	24	24	NUM
ctmj-188	51	9	h	h	NOUN
ctmj-188	51	10	or	or	CCONJ
ctmj-188	51	11	48	48	NUM
ctmj-188	51	12	h	h	NOUN
ctmj-188	51	13	,	,	PUNCT
ctmj-188	51	14	respectively	respectively	ADV
ctmj-188	51	15	.	.	PUNCT
ctmj-188	52	1	the	the	DET
ctmj-188	52	2	culture	culture	NOUN
ctmj-188	52	3	supernatant	supernatant	NOUN
ctmj-188	52	4	was	be	AUX
ctmj-188	52	5	then	then	ADV
ctmj-188	52	6	removed	remove	VERB
ctmj-188	52	7	,	,	PUNCT
ctmj-188	52	8	and	and	CCONJ
ctmj-188	52	9	a	a	DET
ctmj-188	52	10	10	10	NUM
ctmj-188	52	11	%	%	NOUN
ctmj-188	52	12	cck8	cck8	ADJ
ctmj-188	52	13	solution	solution	NOUN
ctmj-188	52	14	was	be	AUX
ctmj-188	52	15	prepared	prepare	VERB
ctmj-188	52	16	by	by	ADP
ctmj-188	52	17	mixing	mix	VERB
ctmj-188	52	18	1	1	NUM
ctmj-188	52	19	ml	ml	NOUN
ctmj-188	52	20	cck8	cck8	ADJ
ctmj-188	52	21	stock	stock	NOUN
ctmj-188	52	22	solution	solution	NOUN
ctmj-188	52	23	with	with	ADP
ctmj-188	52	24	9	9	NUM
ctmj-188	52	25	ml	ml	NOUN
ctmj-188	52	26	phosphate‑buffered	phosphate‑buffere	VERB
ctmj-188	52	27	saline	saline	NOUN
ctmj-188	52	28	(	(	PUNCT
ctmj-188	52	29	pbs	pbs	PROPN
ctmj-188	52	30	)	)	PUNCT
ctmj-188	52	31	.	.	PUNCT
ctmj-188	53	1	then	then	ADV
ctmj-188	53	2	100	100	NUM
ctmj-188	53	3	l	l	NOUN
ctmj-188	53	4	of	of	ADP
ctmj-188	53	5	the	the	DET
ctmj-188	53	6	cck8	cck8	ADJ
ctmj-188	53	7	solution	solution	NOUN
ctmj-188	53	8	was	be	AUX
ctmj-188	53	9	added	add	VERB
ctmj-188	53	10	to	to	ADP
ctmj-188	53	11	each	each	DET
ctmj-188	53	12	well	well	ADV
ctmj-188	53	13	and	and	CCONJ
ctmj-188	53	14	incubated	incubate	VERB
ctmj-188	53	15	for	for	ADP
ctmj-188	53	16	2	2	NUM
ctmj-188	53	17	h	h	NOUN
ctmj-188	53	18	at	at	ADP
ctmj-188	53	19	37	37	NUM
ctmj-188	53	20	°	°	NOUN
ctmj-188	53	21	c	c	NOUN
ctmj-188	53	22	.	.	PUNCT
ctmj-188	54	1	finally	finally	ADV
ctmj-188	54	2	,	,	PUNCT
ctmj-188	54	3	the	the	DET
ctmj-188	54	4	absorbance	absorbance	NOUN
ctmj-188	54	5	at	at	ADP
ctmj-188	54	6	450	450	NUM
ctmj-188	54	7	nm	nm	NOUN
ctmj-188	54	8	was	be	AUX
ctmj-188	54	9	measured	measure	VERB
ctmj-188	54	10	using	use	VERB
ctmj-188	54	11	an	an	DET
ctmj-188	54	12	enzyme	enzyme	NOUN
ctmj-188	54	13	marker	marker	NOUN
ctmj-188	54	14	.	.	PUNCT
ctmj-188	55	1	cell	cell	NOUN
ctmj-188	55	2	viability	viability	NOUN
ctmj-188	55	3	(	(	PUNCT
ctmj-188	55	4	%	%	INTJ
ctmj-188	55	5	)	)	PUNCT
ctmj-188	55	6	was	be	AUX
ctmj-188	55	7	calculated	calculate	VERB
ctmj-188	55	8	as	as	SCONJ
ctmj-188	55	9	follows	follow	VERB
ctmj-188	55	10	:	:	PUNCT
ctmj-188	55	11	cell	cell	NOUN
ctmj-188	55	12	viability	viability	NOUN
ctmj-188	55	13	(	(	PUNCT
ctmj-188	55	14	%	%	INTJ
ctmj-188	55	15	)	)	PUNCT
ctmj-188	55	16	=	=	NOUN
ctmj-188	56	1	a	a	DET
ctmj-188	56	2	value	value	NOUN
ctmj-188	56	3	of	of	ADP
ctmj-188	56	4	experimental	experimental	ADJ
ctmj-188	56	5	group	group	NOUN
ctmj-188	56	6	/	/	SYM
ctmj-188	56	7	a	a	DET
ctmj-188	56	8	value	value	NOUN
ctmj-188	56	9	of	of	ADP
ctmj-188	56	10	control	control	NOUN
ctmj-188	56	11	group	group	NOUN
ctmj-188	56	12	×	×	PROPN
ctmj-188	56	13	100	100	NUM
ctmj-188	56	14	%	%	NOUN
ctmj-188	56	15	drug	drug	NOUN
ctmj-188	56	16	interaction	interaction	NOUN
ctmj-188	56	17	analysis	analysis	NOUN
ctmj-188	56	18	according	accord	VERB
ctmj-188	56	19	to	to	ADP
ctmj-188	56	20	the	the	DET
ctmj-188	56	21	unified	unified	ADJ
ctmj-188	56	22	theory	theory	NOUN
ctmj-188	56	23	of	of	ADP
ctmj-188	56	24	chou	chou	NOUN
ctmj-188	56	25	-	-	PUNCT
ctmj-188	56	26	talalay	talalay	NOUN
ctmj-188	56	27	,	,	PUNCT
ctmj-188	56	28	the	the	DET
ctmj-188	56	29	drug	drug	NOUN
ctmj-188	56	30	interaction	interaction	NOUN
ctmj-188	56	31	between	between	ADP
ctmj-188	56	32	qfg	qfg	NOUN
ctmj-188	56	33	and	and	CCONJ
ctmj-188	56	34	5‑fu	5‑fu	PROPN
ctmj-188	56	35	was	be	AUX
ctmj-188	56	36	calculated	calculate	VERB
ctmj-188	56	37	with	with	ADP
ctmj-188	56	38	compusyn	compusyn	ADJ
ctmj-188	56	39	software	software	NOUN
ctmj-188	56	40	(	(	PUNCT
ctmj-188	56	41	combosyn	combosyn	PROPN
ctmj-188	56	42	,	,	PUNCT
ctmj-188	56	43	inc	inc	PROPN
ctmj-188	56	44	.	.	PROPN
ctmj-188	56	45	,	,	PUNCT
ctmj-188	56	46	new	new	PROPN
ctmj-188	56	47	york	york	PROPN
ctmj-188	56	48	,	,	PUNCT
ctmj-188	56	49	ny	ny	PROPN
ctmj-188	56	50	,	,	PUNCT
ctmj-188	56	51	usa).[15	usa).[15	NOUN
ctmj-188	56	52	]	]	X
ctmj-188	56	53	different	different	ADJ
ctmj-188	56	54	ratio	ratio	NOUN
ctmj-188	56	55	of	of	ADP
ctmj-188	56	56	qfg	qfg	NOUN
ctmj-188	56	57	and	and	CCONJ
ctmj-188	56	58	5‑fu	5‑fu	NUM
ctmj-188	56	59	[	[	X
ctmj-188	56	60	table	table	NOUN
ctmj-188	56	61	1	1	NUM
ctmj-188	56	62	]	]	PUNCT
ctmj-188	56	63	were	be	AUX
ctmj-188	56	64	used	use	VERB
ctmj-188	56	65	to	to	PART
ctmj-188	56	66	quantify	quantify	VERB
ctmj-188	56	67	the	the	DET
ctmj-188	56	68	ci	ci	NOUN
ctmj-188	56	69	,	,	PUNCT
ctmj-188	56	70	which	which	PRON
ctmj-188	56	71	provides	provide	VERB
ctmj-188	56	72	a	a	DET
ctmj-188	56	73	quantitative	quantitative	ADJ
ctmj-188	56	74	representation	representation	NOUN
ctmj-188	56	75	of	of	ADP
ctmj-188	56	76	pharmacological	pharmacological	ADJ
ctmj-188	56	77	interactions	interaction	NOUN
ctmj-188	56	78	to	to	PART
ctmj-188	56	79	assess	assess	VERB
ctmj-188	56	80	drug	drug	NOUN
ctmj-188	56	81	synergy	synergy	NOUN
ctmj-188	56	82	combination	combination	NOUN
ctmj-188	56	83	treatments	treatment	NOUN
ctmj-188	56	84	.	.	PUNCT
ctmj-188	57	1	ci	ci	NOUN
ctmj-188	58	1	<	<	X
ctmj-188	58	2	1	1	NUM
ctmj-188	58	3	indicates	indicate	VERB
ctmj-188	58	4	the	the	DET
ctmj-188	58	5	synergistic	synergistic	ADJ
ctmj-188	58	6	effect	effect	NOUN
ctmj-188	58	7	of	of	ADP
ctmj-188	58	8	qfg	qfg	NOUN
ctmj-188	58	9	and	and	CCONJ
ctmj-188	58	10	5‑fu	5‑fu	PROPN
ctmj-188	58	11	.	.	PUNCT
ctmj-188	59	1	in	in	ADP
ctmj-188	59	2	vivo	vivo	ADJ
ctmj-188	59	3	nude	nude	ADJ
ctmj-188	59	4	mouse	mouse	NOUN
ctmj-188	59	5	transplantation	transplantation	NOUN
ctmj-188	59	6	tumor	tumor	NOUN
ctmj-188	59	7	study	study	VERB
ctmj-188	59	8	a	a	DET
ctmj-188	59	9	total	total	NOUN
ctmj-188	59	10	of	of	ADP
ctmj-188	59	11	4	4	NUM
ctmj-188	59	12	×	×	NOUN
ctmj-188	59	13	106	106	NUM
ctmj-188	59	14	hct-8	hct-8	PUNCT
ctmj-188	59	15	cells	cell	NOUN
ctmj-188	59	16	,	,	PUNCT
ctmj-188	59	17	mixed	mixed	ADJ
ctmj-188	59	18	1:1	1:1	NUM
ctmj-188	59	19	(	(	PUNCT
ctmj-188	59	20	v	v	NOUN
ctmj-188	59	21	:	:	PUNCT
ctmj-188	59	22	v	v	NOUN
ctmj-188	59	23	)	)	PUNCT
ctmj-188	59	24	with	with	ADP
ctmj-188	59	25	matrigel	matrigel	NOUN
ctmj-188	59	26	™	™	NOUN
ctmj-188	59	27	,	,	PUNCT
ctmj-188	59	28	were	be	AUX
ctmj-188	59	29	subcutaneously	subcutaneously	ADV
ctmj-188	59	30	injected	inject	VERB
ctmj-188	59	31	in	in	ADP
ctmj-188	59	32	the	the	DET
ctmj-188	59	33	right	right	ADJ
ctmj-188	59	34	flank	flank	NOUN
ctmj-188	59	35	of	of	ADP
ctmj-188	59	36	the	the	DET
ctmj-188	59	37	mice	mouse	NOUN
ctmj-188	59	38	to	to	PART
ctmj-188	59	39	initiate	initiate	VERB
ctmj-188	59	40	tumor	tumor	NOUN
ctmj-188	59	41	growth	growth	NOUN
ctmj-188	59	42	.	.	PUNCT
ctmj-188	60	1	when	when	SCONJ
ctmj-188	60	2	the	the	DET
ctmj-188	60	3	tumors	tumor	NOUN
ctmj-188	60	4	reached	reach	VERB
ctmj-188	60	5	3	3	NUM
ctmj-188	60	6	mm	mm	NOUN
ctmj-188	60	7	in	in	ADP
ctmj-188	60	8	diameter	diameter	NOUN
ctmj-188	60	9	,	,	PUNCT
ctmj-188	60	10	the	the	DET
ctmj-188	60	11	mice	mouse	NOUN
ctmj-188	60	12	were	be	AUX
ctmj-188	60	13	randomly	randomly	ADV
ctmj-188	60	14	divided	divide	VERB
ctmj-188	60	15	into	into	ADP
ctmj-188	60	16	four	four	NUM
ctmj-188	60	17	groups	group	NOUN
ctmj-188	60	18	(	(	PUNCT
ctmj-188	60	19	n	n	NOUN
ctmj-188	60	20	=	=	NUM
ctmj-188	60	21	10	10	NUM
ctmj-188	60	22	)	)	PUNCT
ctmj-188	60	23	according	accord	VERB
ctmj-188	60	24	to	to	ADP
ctmj-188	60	25	the	the	DET
ctmj-188	60	26	size	size	NOUN
ctmj-188	60	27	of	of	ADP
ctmj-188	60	28	the	the	DET
ctmj-188	60	29	tumors	tumor	NOUN
ctmj-188	60	30	:	:	PUNCT
ctmj-188	60	31	control	control	NOUN
ctmj-188	60	32	group	group	NOUN
ctmj-188	60	33	,	,	PUNCT
ctmj-188	60	34	qfg	qfg	ADJ
ctmj-188	60	35	group	group	NOUN
ctmj-188	60	36	(	(	PUNCT
ctmj-188	60	37	1	1	NUM
ctmj-188	60	38	g	g	NOUN
ctmj-188	60	39	/	/	SYM
ctmj-188	60	40	kg	kg	NOUN
ctmj-188	60	41	)	)	PUNCT
ctmj-188	60	42	,	,	PUNCT
ctmj-188	60	43	5‑fu	5‑fu	PROPN
ctmj-188	60	44	group	group	NOUN
ctmj-188	60	45	(	(	PUNCT
ctmj-188	60	46	25	25	NUM
ctmj-188	60	47	mg	mg	PROPN
ctmj-188	60	48	/	/	SYM
ctmj-188	60	49	kg	kg	PROPN
ctmj-188	60	50	)	)	PUNCT
ctmj-188	60	51	,	,	PUNCT
ctmj-188	60	52	and	and	CCONJ
ctmj-188	60	53	qfg	qfg	VERB
ctmj-188	60	54	+	+	PROPN
ctmj-188	61	1	5‑fu	5‑fu	PROPN
ctmj-188	61	2	group	group	NOUN
ctmj-188	61	3	(	(	PUNCT
ctmj-188	61	4	1	1	NUM
ctmj-188	61	5	g	g	NOUN
ctmj-188	61	6	/	/	SYM
ctmj-188	61	7	kg	kg	NOUN
ctmj-188	62	1	+	+	NOUN
ctmj-188	62	2	25	25	NUM
ctmj-188	62	3	mg	mg	NUM
ctmj-188	62	4	/	/	SYM
ctmj-188	62	5	ml	ml	NOUN
ctmj-188	62	6	)	)	PUNCT
ctmj-188	62	7	.	.	PUNCT
ctmj-188	63	1	the	the	DET
ctmj-188	63	2	drugs	drug	NOUN
ctmj-188	63	3	were	be	AUX
ctmj-188	63	4	administered	administer	VERB
ctmj-188	63	5	immediately	immediately	ADV
ctmj-188	63	6	according	accord	VERB
ctmj-188	63	7	to	to	ADP
ctmj-188	63	8	the	the	DET
ctmj-188	63	9	group	group	NOUN
ctmj-188	63	10	assignment	assignment	NOUN
ctmj-188	63	11	.	.	PUNCT
ctmj-188	64	1	the	the	DET
ctmj-188	64	2	qfg	qfg	ADJ
ctmj-188	64	3	group	group	NOUN
ctmj-188	64	4	was	be	AUX
ctmj-188	64	5	given	give	VERB
ctmj-188	64	6	qfg	qfg	VERB
ctmj-188	64	7	by	by	ADP
ctmj-188	64	8	gavage	gavage	NOUN
ctmj-188	64	9	at	at	ADP
ctmj-188	64	10	a	a	DET
ctmj-188	64	11	dose	dose	NOUN
ctmj-188	64	12	of	of	ADP
ctmj-188	64	13	46	46	NUM
ctmj-188	64	14	ctmj	ctmj	NOUN
ctmj-188	64	15	|	|	ADV
ctmj-188	64	16	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	64	17	chinese	chinese	ADJ
ctmj-188	64	18	traditional	traditional	ADJ
ctmj-188	64	19	medicine	medicine	NOUN
ctmj-188	64	20	journal	journal	NOUN
ctmj-188	64	21	|	|	ADV
ctmj-188	64	22	2025	2025	NUM
ctmj-188	64	23	|	|	ADV
ctmj-188	64	24	vol	vol	NOUN
ctmj-188	64	25	8	8	NUM
ctmj-188	64	26	|issue	|issue	NOUN
ctmj-188	64	27	1	1	NUM
ctmj-188	64	28	46	46	NUM
ctmj-188	64	29	160:1	160:1	NUM
ctmj-188	64	30	0.125:7.81×10−4	0.125:7.81×10−4	PUNCT
ctmj-188	64	31	0.25:1.56×10−3	0.25:1.56×10−3	NUM
ctmj-188	64	32	80:1	80:1	PROPN
ctmj-188	64	33	0.125:1.56×10−3	0.125:1.56×10−3	NUM
ctmj-188	64	34	0.25:3.13×10−3	0.25:3.13×10−3	PROPN
ctmj-188	64	35	40:1	40:1	NUM
ctmj-188	64	36	0.125:3.13×10−3	0.125:3.13×10−3	NUM
ctmj-188	64	37	0.25:6.25×10−3	0.25:6.25×10−3	NUM
ctmj-188	64	38	20:1	20:1	NUM
ctmj-188	64	39	0.125:6.25×10−3	0.125:6.25×10−3	X
ctmj-188	65	1	0.25:1.25×10−2	0.25:1.25×10−2	NUM
ctmj-188	65	2	qfg	qfg	NOUN
ctmj-188	65	3	:	:	PUNCT
ctmj-188	65	4	qingjie	qingjie	PROPN
ctmj-188	65	5	fuzheng	fuzheng	PROPN
ctmj-188	65	6	granule	granule	PROPN
ctmj-188	65	7	,	,	PUNCT
ctmj-188	65	8	fu	fu	ADJ
ctmj-188	65	9	:	:	PUNCT
ctmj-188	65	10	fluorouracil	fluorouracil	NOUN
ctmj-188	65	11	1	1	NUM
ctmj-188	65	12	g	g	NOUN
ctmj-188	65	13	/	/	SYM
ctmj-188	65	14	kg	kg	NOUN
ctmj-188	65	15	.	.	PUNCT
ctmj-188	66	1	the	the	DET
ctmj-188	66	2	5‑fu	5‑fu	PROPN
ctmj-188	66	3	group	group	NOUN
ctmj-188	66	4	was	be	AUX
ctmj-188	66	5	given	give	VERB
ctmj-188	66	6	5‑fu	5‑fu	PROPN
ctmj-188	66	7	intraperitoneally	intraperitoneally	ADV
ctmj-188	66	8	at	at	ADP
ctmj-188	66	9	25	25	NUM
ctmj-188	66	10	mg	mg	PROPN
ctmj-188	66	11	/	/	SYM
ctmj-188	66	12	kg	kg	PROPN
ctmj-188	66	13	.	.	PUNCT
ctmj-188	66	14	qfg	qfg	PROPN
ctmj-188	66	15	+	+	PROPN
ctmj-188	66	16	5‑fu	5‑fu	PROPN
ctmj-188	66	17	group	group	NOUN
ctmj-188	66	18	was	be	AUX
ctmj-188	66	19	given	give	VERB
ctmj-188	66	20	qfg	qfg	NOUN
ctmj-188	66	21	at	at	ADP
ctmj-188	66	22	1	1	NUM
ctmj-188	66	23	g	g	NOUN
ctmj-188	66	24	/	/	SYM
ctmj-188	66	25	kg	kg	NOUN
ctmj-188	66	26	orally	orally	ADV
ctmj-188	66	27	,	,	PUNCT
ctmj-188	66	28	meanwhile	meanwhile	ADV
ctmj-188	66	29	,	,	PUNCT
ctmj-188	66	30	given	give	VERB
ctmj-188	66	31	5‑fu	5‑fu	PRON
ctmj-188	66	32	intraperitoneally	intraperitoneally	ADV
ctmj-188	66	33	at	at	ADP
ctmj-188	66	34	25	25	NUM
ctmj-188	66	35	mg/	mg/	ADJ
ctmj-188	66	36	kg	kg	PROPN
ctmj-188	66	37	.	.	PUNCT
ctmj-188	67	1	the	the	DET
ctmj-188	67	2	control	control	NOUN
ctmj-188	67	3	group	group	NOUN
ctmj-188	67	4	was	be	AUX
ctmj-188	67	5	given	give	VERB
ctmj-188	67	6	the	the	DET
ctmj-188	67	7	same	same	ADJ
ctmj-188	67	8	volume	volume	NOUN
ctmj-188	67	9	of	of	ADP
ctmj-188	67	10	saline	saline	NOUN
ctmj-188	67	11	.	.	PUNCT
ctmj-188	68	1	qfg	qfg	PROPN
ctmj-188	68	2	was	be	AUX
ctmj-188	68	3	administered	administer	VERB
ctmj-188	68	4	once	once	ADV
ctmj-188	68	5	a	a	DET
ctmj-188	68	6	day	day	NOUN
ctmj-188	68	7	for	for	ADP
ctmj-188	68	8	6	6	NUM
ctmj-188	68	9	consecutive	consecutive	ADJ
ctmj-188	68	10	days	day	NOUN
ctmj-188	68	11	per	per	ADP
ctmj-188	68	12	week	week	NOUN
ctmj-188	68	13	;	;	PUNCT
ctmj-188	68	14	5‑fu	5‑fu	PROPN
ctmj-188	68	15	was	be	AUX
ctmj-188	68	16	injected	inject	VERB
ctmj-188	68	17	once	once	ADV
ctmj-188	68	18	every	every	DET
ctmj-188	68	19	other	other	ADJ
ctmj-188	68	20	day	day	NOUN
ctmj-188	68	21	.	.	PUNCT
ctmj-188	69	1	the	the	DET
ctmj-188	69	2	length	length	NOUN
ctmj-188	69	3	(	(	PUNCT
ctmj-188	69	4	l	l	NOUN
ctmj-188	69	5	)	)	PUNCT
ctmj-188	69	6	and	and	CCONJ
ctmj-188	69	7	width	width	ADJ
ctmj-188	69	8	(	(	PUNCT
ctmj-188	69	9	w	w	NOUN
ctmj-188	69	10	)	)	PUNCT
ctmj-188	69	11	of	of	ADP
ctmj-188	69	12	the	the	DET
ctmj-188	69	13	tumors	tumor	NOUN
ctmj-188	69	14	were	be	AUX
ctmj-188	69	15	recorded	record	VERB
ctmj-188	69	16	every	every	DET
ctmj-188	69	17	other	other	ADJ
ctmj-188	69	18	day	day	NOUN
ctmj-188	69	19	,	,	PUNCT
ctmj-188	69	20	and	and	CCONJ
ctmj-188	69	21	calculated	calculate	VERB
ctmj-188	69	22	the	the	DET
ctmj-188	69	23	tumor	tumor	NOUN
ctmj-188	69	24	volume	volume	NOUN
ctmj-188	69	25	as	as	ADP
ctmj-188	69	26	the	the	DET
ctmj-188	69	27	following	follow	VERB
ctmj-188	69	28	formula	formula	NOUN
ctmj-188	69	29	:	:	PUNCT
ctmj-188	69	30	tumor	tumor	NOUN
ctmj-188	69	31	volume	volume	NOUN
ctmj-188	69	32	=	=	PUNCT
ctmj-188	69	33	/6	/6	ADJ
ctmj-188	69	34	×	×	NOUN
ctmj-188	69	35	l	l	NOUN
ctmj-188	69	36	×	×	NOUN
ctmj-188	69	37	w2	w2	NOUN
ctmj-188	69	38	.	.	PUNCT
ctmj-188	70	1	during	during	ADP
ctmj-188	70	2	the	the	DET
ctmj-188	70	3	experiment	experiment	NOUN
ctmj-188	70	4	,	,	PUNCT
ctmj-188	70	5	the	the	DET
ctmj-188	70	6	weight	weight	NOUN
ctmj-188	70	7	of	of	ADP
ctmj-188	70	8	each	each	DET
ctmj-188	70	9	nude	nude	ADJ
ctmj-188	70	10	mouse	mouse	NOUN
ctmj-188	70	11	was	be	AUX
ctmj-188	70	12	recorded	record	VERB
ctmj-188	70	13	.	.	PUNCT
ctmj-188	71	1	at	at	ADP
ctmj-188	71	2	the	the	DET
ctmj-188	71	3	end	end	NOUN
ctmj-188	71	4	of	of	ADP
ctmj-188	71	5	the	the	DET
ctmj-188	71	6	experiment	experiment	NOUN
ctmj-188	71	7	,	,	PUNCT
ctmj-188	71	8	the	the	DET
ctmj-188	71	9	animals	animal	NOUN
ctmj-188	71	10	were	be	AUX
ctmj-188	71	11	anesthetized	anesthetize	VERB
ctmj-188	71	12	,	,	PUNCT
ctmj-188	71	13	the	the	DET
ctmj-188	71	14	tumors	tumor	NOUN
ctmj-188	71	15	were	be	AUX
ctmj-188	71	16	excised	excise	VERB
ctmj-188	71	17	and	and	CCONJ
ctmj-188	71	18	weighed	weigh	VERB
ctmj-188	71	19	.	.	PUNCT
ctmj-188	72	1	colony	colony	NOUN
ctmj-188	72	2	formation	formation	NOUN
ctmj-188	72	3	treatment	treatment	NOUN
ctmj-188	72	4	with	with	ADP
ctmj-188	72	5	qfg	qfg	NOUN
ctmj-188	72	6	(	(	PUNCT
ctmj-188	72	7	0.25	0.25	NUM
ctmj-188	72	8	mg	mg	PROPN
ctmj-188	72	9	/	/	SYM
ctmj-188	72	10	ml	ml	NOUN
ctmj-188	72	11	)	)	PUNCT
ctmj-188	72	12	,	,	PUNCT
ctmj-188	72	13	5‑fu	5‑fu	PROPN
ctmj-188	72	14	(	(	PUNCT
ctmj-188	72	15	3.13	3.13	NUM
ctmj-188	72	16	g	g	NOUN
ctmj-188	72	17	/	/	SYM
ctmj-188	72	18	ml	ml	NOUN
ctmj-188	72	19	)	)	PUNCT
ctmj-188	72	20	and	and	CCONJ
ctmj-188	72	21	the	the	DET
ctmj-188	72	22	combination	combination	NOUN
ctmj-188	72	23	for	for	ADP
ctmj-188	72	24	24	24	NUM
ctmj-188	72	25	h.	h.	PROPN
ctmj-188	72	26	control	control	PROPN
ctmj-188	72	27	cells	cell	NOUN
ctmj-188	72	28	(	(	PUNCT
ctmj-188	72	29	untreated	untreated	ADJ
ctmj-188	72	30	)	)	PUNCT
ctmj-188	72	31	were	be	AUX
ctmj-188	72	32	also	also	ADV
ctmj-188	72	33	processed	process	VERB
ctmj-188	72	34	in	in	ADP
ctmj-188	72	35	parallel	parallel	NOUN
ctmj-188	72	36	.	.	PUNCT
ctmj-188	73	1	then	then	ADV
ctmj-188	73	2	500	500	NUM
ctmj-188	73	3	cells	cell	NOUN
ctmj-188	73	4	/	/	SYM
ctmj-188	74	1	well	well	INTJ
ctmj-188	74	2	were	be	AUX
ctmj-188	74	3	collected	collect	VERB
ctmj-188	74	4	and	and	CCONJ
ctmj-188	74	5	seeded	seed	VERB
ctmj-188	74	6	into	into	ADP
ctmj-188	74	7	12‑well	12‑well	NUM
ctmj-188	74	8	plates	plate	NOUN
ctmj-188	74	9	and	and	CCONJ
ctmj-188	74	10	incubated	incubate	VERB
ctmj-188	74	11	for	for	ADP
ctmj-188	74	12	8	8	NUM
ctmj-188	74	13	days	day	NOUN
ctmj-188	74	14	,	,	PUNCT
ctmj-188	74	15	fixed	fix	VERB
ctmj-188	74	16	with	with	ADP
ctmj-188	74	17	4	4	NUM
ctmj-188	74	18	%	%	NOUN
ctmj-188	74	19	paraformaldehyde	paraformaldehyde	NOUN
ctmj-188	74	20	(	(	PUNCT
ctmj-188	74	21	1	1	NUM
ctmj-188	74	22	ml	ml	NOUN
ctmj-188	74	23	/	/	SYM
ctmj-188	74	24	well	well	NOUN
ctmj-188	74	25	)	)	PUNCT
ctmj-188	74	26	for	for	ADP
ctmj-188	74	27	20	20	NUM
ctmj-188	74	28	min	min	NOUN
ctmj-188	74	29	and	and	CCONJ
ctmj-188	74	30	stained	stain	VERB
ctmj-188	74	31	with	with	ADP
ctmj-188	74	32	0.1	0.1	NUM
ctmj-188	74	33	%	%	NOUN
ctmj-188	74	34	crystal	crystal	NOUN
ctmj-188	74	35	violet	violet	NOUN
ctmj-188	74	36	for	for	ADP
ctmj-188	74	37	another	another	DET
ctmj-188	74	38	20	20	NUM
ctmj-188	74	39	min	min	NOUN
ctmj-188	74	40	.	.	PROPN
ctmj-188	75	1	finally	finally	ADV
ctmj-188	75	2	,	,	PUNCT
ctmj-188	75	3	the	the	DET
ctmj-188	75	4	number	number	NOUN
ctmj-188	75	5	of	of	ADP
ctmj-188	75	6	clones	clone	NOUN
ctmj-188	75	7	was	be	AUX
ctmj-188	75	8	counted	count	VERB
ctmj-188	75	9	.	.	PUNCT
ctmj-188	76	1	flow	flow	NOUN
ctmj-188	76	2	cytometry	cytometry	NOUN
ctmj-188	76	3	treatment	treatment	NOUN
ctmj-188	76	4	with	with	ADP
ctmj-188	76	5	different	different	ADJ
ctmj-188	76	6	drugs	drug	NOUN
ctmj-188	76	7	for	for	ADP
ctmj-188	76	8	24	24	NUM
ctmj-188	76	9	h	h	NOUN
ctmj-188	76	10	,	,	PUNCT
ctmj-188	76	11	1	1	NUM
ctmj-188	76	12	×	×	NOUN
ctmj-188	76	13	106	106	NUM
ctmj-188	76	14	cells	cell	NOUN
ctmj-188	76	15	were	be	AUX
ctmj-188	76	16	collected	collect	VERB
ctmj-188	76	17	,	,	PUNCT
ctmj-188	76	18	and	and	CCONJ
ctmj-188	76	19	re	re	VERB
ctmj-188	76	20	-	-	VERB
ctmj-188	76	21	suspended	suspend	VERB
ctmj-188	76	22	in	in	ADP
ctmj-188	76	23	500	500	NUM
ctmj-188	76	24	l	l	NOUN
ctmj-188	76	25	of	of	ADP
ctmj-188	76	26	1×	1×	NUM
ctmj-188	76	27	binding	bind	VERB
ctmj-188	76	28	buffer	buffer	NOUN
ctmj-188	76	29	followed	follow	VERB
ctmj-188	76	30	by	by	ADP
ctmj-188	76	31	washed	wash	VERB
ctmj-188	76	32	twice	twice	ADV
ctmj-188	76	33	with	with	ADP
ctmj-188	76	34	cold	cold	ADJ
ctmj-188	76	35	pbs	pbs	PROPN
ctmj-188	76	36	.	.	PUNCT
ctmj-188	77	1	annexin	annexin	PROPN
ctmj-188	77	2	v‑fitc	v‑fitc	PROPN
ctmj-188	77	3	and	and	CCONJ
ctmj-188	77	4	pi	pi	PROPN
ctmj-188	77	5	(	(	PUNCT
ctmj-188	77	6	both	both	PRON
ctmj-188	77	7	5	5	NUM
ctmj-188	77	8	l	l	NOUN
ctmj-188	77	9	)	)	PUNCT
ctmj-188	77	10	were	be	AUX
ctmj-188	77	11	added	add	VERB
ctmj-188	77	12	and	and	CCONJ
ctmj-188	77	13	incubated	incubate	VERB
ctmj-188	77	14	for	for	ADP
ctmj-188	77	15	an	an	DET
ctmj-188	77	16	additional	additional	ADJ
ctmj-188	77	17	15	15	NUM
ctmj-188	77	18	min	min	NOUN
ctmj-188	77	19	in	in	ADP
ctmj-188	77	20	the	the	DET
ctmj-188	77	21	dark	dark	NOUN
ctmj-188	77	22	.	.	PUNCT
ctmj-188	78	1	for	for	ADP
ctmj-188	78	2	each	each	DET
ctmj-188	78	3	sample	sample	NOUN
ctmj-188	78	4	,	,	PUNCT
ctmj-188	78	5	10,000	10,000	NUM
ctmj-188	78	6	events	event	NOUN
ctmj-188	78	7	were	be	AUX
ctmj-188	78	8	collected	collect	VERB
ctmj-188	78	9	and	and	CCONJ
ctmj-188	78	10	analyzed	analyze	VERB
ctmj-188	78	11	.	.	PUNCT
ctmj-188	79	1	4’,6‑diamidino‑2‑phenylindole	4’,6‑diamidino‑2‑phenylindole	NUM
ctmj-188	79	2	staining	stain	VERB
ctmj-188	79	3	assay	assay	ADJ
ctmj-188	79	4	twenty	twenty	NUM
ctmj-188	79	5	-	-	PUNCT
ctmj-188	79	6	four	four	NUM
ctmj-188	79	7	hours	hour	NOUN
ctmj-188	79	8	after	after	SCONJ
ctmj-188	79	9	treated	treat	VERB
ctmj-188	79	10	with	with	ADP
ctmj-188	79	11	different	different	ADJ
ctmj-188	79	12	drugs	drug	NOUN
ctmj-188	79	13	,	,	PUNCT
ctmj-188	79	14	4’,6‑diamidino‑2‑phenylindole	4’,6‑diamidino‑2‑phenylindole	PROPN
ctmj-188	79	15	(	(	PUNCT
ctmj-188	79	16	dapi	dapi	ADJ
ctmj-188	79	17	)	)	PUNCT
ctmj-188	79	18	staining	stain	VERB
ctmj-188	79	19	was	be	AUX
ctmj-188	79	20	performed	perform	VERB
ctmj-188	79	21	.	.	PUNCT
ctmj-188	80	1	in	in	ADP
ctmj-188	80	2	brief	brief	NOUN
ctmj-188	80	3	,	,	PUNCT
ctmj-188	80	4	the	the	DET
ctmj-188	80	5	cells	cell	NOUN
ctmj-188	80	6	were	be	AUX
ctmj-188	80	7	fixed	fix	VERB
ctmj-188	80	8	with	with	ADP
ctmj-188	80	9	4	4	NUM
ctmj-188	80	10	%	%	NOUN
ctmj-188	80	11	paraformaldehyde	paraformaldehyde	NOUN
ctmj-188	80	12	for	for	ADP
ctmj-188	80	13	15	15	NUM
ctmj-188	80	14	min	min	NOUN
ctmj-188	80	15	,	,	PUNCT
ctmj-188	80	16	followed	follow	VERB
ctmj-188	80	17	by	by	ADP
ctmj-188	80	18	three	three	NUM
ctmj-188	80	19	washes	wash	NOUN
ctmj-188	80	20	with	with	ADP
ctmj-188	80	21	pbs	pbs	PROPN
ctmj-188	80	22	.	.	PUNCT
ctmj-188	81	1	next	next	ADJ
ctmj-188	81	2	,	,	PUNCT
ctmj-188	81	3	10	10	NUM
ctmj-188	81	4	%	%	NOUN
ctmj-188	81	5	dapi	dapi	ADJ
ctmj-188	81	6	staining	stain	VERB
ctmj-188	81	7	solution	solution	NOUN
ctmj-188	81	8	was	be	AUX
ctmj-188	81	9	added	add	VERB
ctmj-188	81	10	and	and	CCONJ
ctmj-188	81	11	incuated	incuate	VERB
ctmj-188	81	12	for	for	ADP
ctmj-188	81	13	15	15	NUM
ctmj-188	81	14	min	min	NOUN
ctmj-188	81	15	in	in	ADP
ctmj-188	81	16	the	the	DET
ctmj-188	81	17	dark	dark	NOUN
ctmj-188	81	18	,	,	PUNCT
ctmj-188	81	19	then	then	ADV
ctmj-188	81	20	imaged	image	VERB
ctmj-188	81	21	using	use	VERB
ctmj-188	81	22	a	a	DET
ctmj-188	81	23	fluorescence	fluorescence	NOUN
ctmj-188	81	24	microscope	microscope	NOUN
ctmj-188	81	25	(	(	PUNCT
ctmj-188	81	26	×200	×200	PROPN
ctmj-188	81	27	)	)	PUNCT
ctmj-188	81	28	.	.	PUNCT
ctmj-188	82	1	migration	migration	NOUN
ctmj-188	82	2	and	and	CCONJ
ctmj-188	82	3	invasion	invasion	NOUN
ctmj-188	82	4	assay	assay	VERB
ctmj-188	82	5	twenty‑four	twenty‑four	NUM
ctmj-188	82	6	hours	hour	NOUN
ctmj-188	82	7	after	after	SCONJ
ctmj-188	82	8	treated	treat	VERB
ctmj-188	82	9	with	with	ADP
ctmj-188	82	10	different	different	ADJ
ctmj-188	82	11	drugs	drug	NOUN
ctmj-188	82	12	,	,	PUNCT
ctmj-188	82	13	50,000	50,000	NUM
ctmj-188	82	14	hct-8	hct-8	NUM
ctmj-188	82	15	cells	cell	NOUN
ctmj-188	82	16	were	be	AUX
ctmj-188	82	17	seeded	seed	VERB
ctmj-188	82	18	in	in	ADP
ctmj-188	82	19	the	the	DET
ctmj-188	82	20	upper	upper	ADJ
ctmj-188	82	21	chamber	chamber	NOUN
ctmj-188	82	22	of	of	ADP
ctmj-188	82	23	transwell	transwell	PROPN
ctmj-188	82	24	plates	plate	NOUN
ctmj-188	82	25	.	.	PUNCT
ctmj-188	83	1	matrigel	matrigel	NOUN
ctmj-188	83	2	coating	coating	NOUN
ctmj-188	83	3	was	be	AUX
ctmj-188	83	4	applied	apply	VERB
ctmj-188	83	5	for	for	SCONJ
ctmj-188	83	6	the	the	DET
ctmj-188	83	7	invasion	invasion	NOUN
ctmj-188	83	8	assay	assay	VERB
ctmj-188	83	9	,	,	PUNCT
ctmj-188	83	10	while	while	SCONJ
ctmj-188	83	11	no	no	DET
ctmj-188	83	12	matrigel	matrigel	NOUN
ctmj-188	83	13	was	be	AUX
ctmj-188	83	14	used	use	VERB
ctmj-188	83	15	for	for	ADP
ctmj-188	83	16	the	the	DET
ctmj-188	83	17	migration	migration	NOUN
ctmj-188	83	18	assay	assay	VERB
ctmj-188	83	19	.	.	PUNCT
ctmj-188	84	1	the	the	DET
ctmj-188	84	2	upper	upper	ADJ
ctmj-188	84	3	chamber	chamber	NOUN
ctmj-188	84	4	contained	contain	VERB
ctmj-188	84	5	rpmi‑1640	rpmi‑1640	PROPN
ctmj-188	84	6	basic	basic	ADJ
ctmj-188	84	7	midium	midium	NOUN
ctmj-188	84	8	,	,	PUNCT
ctmj-188	84	9	and	and	CCONJ
ctmj-188	84	10	the	the	DET
ctmj-188	84	11	lower	low	ADJ
ctmj-188	84	12	chamber	chamber	NOUN
ctmj-188	84	13	contained	contain	VERB
ctmj-188	84	14	700	700	NUM
ctmj-188	84	15	l	l	NOUN
ctmj-188	84	16	of	of	ADP
ctmj-188	84	17	rpmi‑1640	rpmi‑1640	PROPN
ctmj-188	84	18	with	with	ADP
ctmj-188	84	19	fbs	fbs	PROPN
ctmj-188	84	20	.	.	PUNCT
ctmj-188	85	1	the	the	DET
ctmj-188	85	2	plates	plate	NOUN
ctmj-188	85	3	were	be	AUX
ctmj-188	85	4	incubated	incubate	VERB
ctmj-188	85	5	at	at	ADP
ctmj-188	85	6	37	37	NUM
ctmj-188	85	7	°	°	ADP
ctmj-188	85	8	c	c	NOUN
ctmj-188	85	9	for	for	ADP
ctmj-188	85	10	14	14	NUM
ctmj-188	85	11	h.	h.	NOUN
ctmj-188	85	12	then	then	ADV
ctmj-188	85	13	,	,	PUNCT
ctmj-188	85	14	the	the	DET
ctmj-188	85	15	both	both	CCONJ
ctmj-188	85	16	the	the	DET
ctmj-188	85	17	upper	upper	ADJ
ctmj-188	85	18	and	and	CCONJ
ctmj-188	85	19	lower	low	ADJ
ctmj-188	85	20	chambers	chamber	NOUN
ctmj-188	85	21	were	be	AUX
ctmj-188	85	22	fixed	fix	VERB
ctmj-188	85	23	with	with	ADP
ctmj-188	85	24	4	4	NUM
ctmj-188	85	25	%	%	NOUN
ctmj-188	85	26	paraformaldehyde	paraformaldehyde	NOUN
ctmj-188	85	27	for	for	ADP
ctmj-188	85	28	20	20	NUM
ctmj-188	85	29	min	min	NOUN
ctmj-188	85	30	,	,	PUNCT
ctmj-188	85	31	and	and	CCONJ
ctmj-188	85	32	stained	stain	VERB
ctmj-188	85	33	with	with	ADP
ctmj-188	85	34	crystal	crystal	PROPN
ctmj-188	85	35	violet	violet	NOUN
ctmj-188	85	36	for	for	ADP
ctmj-188	85	37	15	15	NUM
ctmj-188	85	38	min	min	NOUN
ctmj-188	85	39	.	.	PROPN
ctmj-188	86	1	finally	finally	ADV
ctmj-188	86	2	,	,	PUNCT
ctmj-188	86	3	cells	cell	NOUN
ctmj-188	86	4	in	in	ADP
ctmj-188	86	5	the	the	DET
ctmj-188	86	6	lower	low	ADJ
ctmj-188	86	7	layer	layer	NOUN
ctmj-188	86	8	of	of	ADP
ctmj-188	86	9	chamber	chamber	NOUN
ctmj-188	86	10	was	be	AUX
ctmj-188	86	11	photographed	photograph	VERB
ctmj-188	86	12	using	use	VERB
ctmj-188	86	13	an	an	DET
ctmj-188	86	14	inverted	inverted	ADJ
ctmj-188	86	15	microscope	microscope	NOUN
ctmj-188	86	16	(	(	PUNCT
ctmj-188	86	17	×200	×200	PROPN
ctmj-188	86	18	)	)	PUNCT
ctmj-188	86	19	.	.	PUNCT
ctmj-188	87	1	western	western	ADJ
ctmj-188	87	2	blot	blot	NOUN
ctmj-188	87	3	the	the	DET
ctmj-188	87	4	proteins	protein	NOUN
ctmj-188	87	5	were	be	AUX
ctmj-188	87	6	extracted	extract	VERB
ctmj-188	87	7	using	use	VERB
ctmj-188	87	8	radioimmunoassay	radioimmunoassay	ADJ
ctmj-188	87	9	buffer	buffer	NOUN
ctmj-188	87	10	containing	contain	VERB
ctmj-188	87	11	inhibitor	inhibitor	NOUN
ctmj-188	87	12	cocktail	cocktail	NOUN
ctmj-188	87	13	(	(	PUNCT
ctmj-188	87	14	thermo	thermo	NOUN
ctmj-188	87	15	fisher	fisher	PROPN
ctmj-188	87	16	scientific	scientific	PROPN
ctmj-188	87	17	,	,	PUNCT
ctmj-188	87	18	usa	usa	PROPN
ctmj-188	87	19	)	)	PUNCT
ctmj-188	87	20	.	.	PUNCT
ctmj-188	88	1	the	the	DET
ctmj-188	88	2	samples	sample	NOUN
ctmj-188	88	3	were	be	AUX
ctmj-188	88	4	then	then	ADV
ctmj-188	88	5	centrifuged	centrifuge	VERB
ctmj-188	88	6	and	and	CCONJ
ctmj-188	88	7	obtain	obtain	VERB
ctmj-188	88	8	final	final	ADJ
ctmj-188	88	9	supernatants	supernatant	NOUN
ctmj-188	88	10	.	.	PUNCT
ctmj-188	89	1	the	the	DET
ctmj-188	89	2	concentration	concentration	NOUN
ctmj-188	89	3	of	of	ADP
ctmj-188	89	4	total	total	ADJ
ctmj-188	89	5	protein	protein	NOUN
ctmj-188	89	6	was	be	AUX
ctmj-188	89	7	detected	detect	VERB
ctmj-188	89	8	with	with	ADP
ctmj-188	89	9	bca	bca	PROPN
ctmj-188	89	10	(	(	PUNCT
ctmj-188	89	11	bovine	bovine	NOUN
ctmj-188	89	12	serum	serum	NOUN
ctmj-188	89	13	albumin	albumin	NOUN
ctmj-188	89	14	)	)	PUNCT
ctmj-188	89	15	protein	protein	NOUN
ctmj-188	89	16	assay	assay	NOUN
ctmj-188	89	17	kit	kit	NOUN
ctmj-188	89	18	(	(	PUNCT
ctmj-188	89	19	thermo	thermo	NOUN
ctmj-188	89	20	fisher	fisher	PROPN
ctmj-188	89	21	scientific	scientific	PROPN
ctmj-188	89	22	,	,	PUNCT
ctmj-188	89	23	usa	usa	PROPN
ctmj-188	89	24	)	)	PUNCT
ctmj-188	89	25	.	.	PUNCT
ctmj-188	90	1	the	the	DET
ctmj-188	90	2	proteins	protein	NOUN
ctmj-188	90	3	(	(	PUNCT
ctmj-188	90	4	30	30	NUM
ctmj-188	90	5	g	g	NOUN
ctmj-188	90	6	)	)	PUNCT
ctmj-188	90	7	that	that	PRON
ctmj-188	90	8	were	be	AUX
ctmj-188	90	9	denatured	denature	VERB
ctmj-188	90	10	at	at	ADP
ctmj-188	90	11	100	100	NUM
ctmj-188	90	12	°	°	NOUN
ctmj-188	90	13	c	c	NOUN
ctmj-188	90	14	in	in	ADP
ctmj-188	90	15	a	a	DET
ctmj-188	90	16	metal	metal	NOUN
ctmj-188	90	17	bath	bath	NOUN
ctmj-188	90	18	were	be	AUX
ctmj-188	90	19	resolved	resolve	VERB
ctmj-188	90	20	by	by	ADP
ctmj-188	90	21	sodium	sodium	NOUN
ctmj-188	90	22	dodecyl	dodecyl	PROPN
ctmj-188	90	23	sulfate	sulfate	NOUN
ctmj-188	90	24	-	-	PUNCT
ctmj-188	90	25	polyacrylamide	polyacrylamide	NOUN
ctmj-188	90	26	gel	gel	NOUN
ctmj-188	90	27	electrophoresis	electrophoresis	NOUN
ctmj-188	90	28	and	and	CCONJ
ctmj-188	90	29	electro	electro	NOUN
ctmj-188	90	30	-	-	PUNCT
ctmj-188	90	31	transferred	transfer	VERB
ctmj-188	90	32	to	to	ADP
ctmj-188	90	33	polyvinylidene	polyvinylidene	NOUN
ctmj-188	90	34	difluoride	difluoride	NOUN
ctmj-188	90	35	membranes	membrane	NOUN
ctmj-188	90	36	,	,	PUNCT
ctmj-188	90	37	sealed	seal	VERB
ctmj-188	90	38	with	with	ADP
ctmj-188	90	39	5	5	NUM
ctmj-188	90	40	%	%	NOUN
ctmj-188	90	41	milk	milk	NOUN
ctmj-188	90	42	and	and	CCONJ
ctmj-188	90	43	incubated	incubate	VERB
ctmj-188	90	44	with	with	ADP
ctmj-188	90	45	primary	primary	ADJ
ctmj-188	90	46	antibodies	antibody	NOUN
ctmj-188	90	47	(	(	PUNCT
ctmj-188	90	48	1:1000	1:1000	NUM
ctmj-188	90	49	)	)	PUNCT
ctmj-188	90	50	at	at	ADP
ctmj-188	90	51	4	4	NUM
ctmj-188	90	52	°	°	NOUN
ctmj-188	90	53	c	c	NOUN
ctmj-188	90	54	overnight	overnight	ADV
ctmj-188	90	55	.	.	PUNCT
ctmj-188	91	1	after	after	SCONJ
ctmj-188	91	2	the	the	DET
ctmj-188	91	3	membranes	membrane	NOUN
ctmj-188	91	4	were	be	AUX
ctmj-188	91	5	incubated	incubate	VERB
ctmj-188	91	6	with	with	ADP
ctmj-188	91	7	the	the	DET
ctmj-188	91	8	corresponding	corresponding	ADJ
ctmj-188	91	9	secondary	secondary	ADJ
ctmj-188	91	10	antibodies	antibody	NOUN
ctmj-188	91	11	(	(	PUNCT
ctmj-188	91	12	hrp‑conjugated	hrp‑conjugate	VERB
ctmj-188	91	13	1:5000	1:5000	NUM
ctmj-188	91	14	)	)	PUNCT
ctmj-188	91	15	for	for	ADP
ctmj-188	91	16	1	1	NUM
ctmj-188	91	17	h	h	NOUN
ctmj-188	91	18	at	at	ADP
ctmj-188	91	19	25	25	NUM
ctmj-188	91	20	°	°	NOUN
ctmj-188	91	21	c	c	NOUN
ctmj-188	91	22	,	,	PUNCT
ctmj-188	91	23	the	the	DET
ctmj-188	91	24	image	image	NOUN
ctmj-188	91	25	lab	lab	NOUN
ctmj-188	91	26	(	(	PUNCT
ctmj-188	91	27	bio‑rad	bio‑rad	PROPN
ctmj-188	91	28	laboratories	laboratory	NOUN
ctmj-188	91	29	,	,	PUNCT
ctmj-188	91	30	inc	inc	PROPN
ctmj-188	91	31	.	.	PROPN
ctmj-188	91	32	,	,	PUNCT
ctmj-188	91	33	berkley	berkley	PROPN
ctmj-188	91	34	,	,	PUNCT
ctmj-188	91	35	california	california	PROPN
ctmj-188	91	36	,	,	PUNCT
ctmj-188	91	37	usa	usa	PROPN
ctmj-188	91	38	)	)	PUNCT
ctmj-188	91	39	was	be	AUX
ctmj-188	91	40	used	use	VERB
ctmj-188	91	41	to	to	PART
ctmj-188	91	42	detect	detect	VERB
ctmj-188	91	43	proteins	protein	NOUN
ctmj-188	91	44	.	.	PUNCT
ctmj-188	92	1	immunohistochemistry	immunohistochemistry	NOUN
ctmj-188	92	2	after	after	ADP
ctmj-188	92	3	inactivation	inactivation	NOUN
ctmj-188	92	4	of	of	ADP
ctmj-188	92	5	endogenous	endogenous	ADJ
ctmj-188	92	6	peroxidase	peroxidase	NOUN
ctmj-188	92	7	with	with	ADP
ctmj-188	92	8	3	3	NUM
ctmj-188	92	9	%	%	NOUN
ctmj-188	92	10	hydrogen	hydrogen	NOUN
ctmj-188	92	11	peroxide	peroxide	NOUN
ctmj-188	92	12	and	and	CCONJ
ctmj-188	92	13	blocked	block	VERB
ctmj-188	92	14	with	with	ADP
ctmj-188	92	15	goat	goat	PROPN
ctmj-188	92	16	serum	serum	PROPN
ctmj-188	92	17	(	(	PUNCT
ctmj-188	92	18	g9023	g9023	PROPN
ctmj-188	92	19	,	,	PUNCT
ctmj-188	92	20	sigma	sigma	NOUN
ctmj-188	92	21	)	)	PUNCT
ctmj-188	92	22	,	,	PUNCT
ctmj-188	92	23	the	the	DET
ctmj-188	92	24	slides	slide	NOUN
ctmj-188	92	25	were	be	AUX
ctmj-188	92	26	incubated	incubate	VERB
ctmj-188	92	27	with	with	ADP
ctmj-188	92	28	primary	primary	ADJ
ctmj-188	92	29	antibodies	antibody	NOUN
ctmj-188	92	30	against	against	ADP
ctmj-188	92	31	ki‑67	ki‑67	PROPN
ctmj-188	92	32	(	(	PUNCT
ctmj-188	92	33	1:200	1:200	NUM
ctmj-188	92	34	)	)	PUNCT
ctmj-188	92	35	at	at	ADP
ctmj-188	92	36	4	4	NUM
ctmj-188	92	37	°	°	NOUN
ctmj-188	92	38	c	c	NOUN
ctmj-188	92	39	overnight	overnight	ADV
ctmj-188	92	40	.	.	PUNCT
ctmj-188	93	1	on	on	ADP
ctmj-188	93	2	the	the	DET
ctmj-188	93	3	following	following	ADJ
ctmj-188	93	4	day	day	NOUN
ctmj-188	93	5	,	,	PUNCT
ctmj-188	93	6	the	the	DET
ctmj-188	93	7	slides	slide	NOUN
ctmj-188	93	8	were	be	AUX
ctmj-188	93	9	incubated	incubate	VERB
ctmj-188	93	10	with	with	ADP
ctmj-188	93	11	biotinylated	biotinylated	ADJ
ctmj-188	93	12	secondary	secondary	ADJ
ctmj-188	93	13	antibodies	antibody	NOUN
ctmj-188	93	14	(	(	PUNCT
ctmj-188	93	15	kit‑9710	kit‑9710	X
ctmj-188	93	16	,	,	PUNCT
ctmj-188	93	17	mxb	mxb	NOUN
ctmj-188	93	18	biotechnologies	biotechnology	NOUN
ctmj-188	93	19	,	,	PUNCT
ctmj-188	93	20	china	china	PROPN
ctmj-188	93	21	)	)	PUNCT
ctmj-188	93	22	and	and	CCONJ
ctmj-188	93	23	streptavidin	streptavidin	NOUN
ctmj-188	93	24	peroxidase	peroxidase	NOUN
ctmj-188	93	25	(	(	PUNCT
ctmj-188	93	26	kit‑9710	kit‑9710	PROPN
ctmj-188	93	27	,	,	PUNCT
ctmj-188	93	28	mxb	mxb	NOUN
ctmj-188	93	29	biotechnologies	biotechnology	NOUN
ctmj-188	93	30	china	china	PROPN
ctmj-188	93	31	)	)	PUNCT
ctmj-188	93	32	at	at	ADP
ctmj-188	93	33	37	37	NUM
ctmj-188	93	34	°	°	NOUN
ctmj-188	93	35	c	c	NOUN
ctmj-188	93	36	,	,	PUNCT
ctmj-188	93	37	respectively	respectively	ADV
ctmj-188	93	38	.	.	PUNCT
ctmj-188	94	1	after	after	ADP
ctmj-188	94	2	for	for	ADP
ctmj-188	94	3	a	a	DET
ctmj-188	94	4	30	30	NUM
ctmj-188	94	5	min	min	NOUN
ctmj-188	94	6	incubation	incubation	NOUN
ctmj-188	94	7	,	,	PUNCT
ctmj-188	94	8	the	the	DET
ctmj-188	94	9	slides	slide	NOUN
ctmj-188	94	10	were	be	AUX
ctmj-188	94	11	washed	wash	VERB
ctmj-188	94	12	3	3	NUM
ctmj-188	94	13	times	time	NOUN
ctmj-188	94	14	with	with	ADP
ctmj-188	94	15	pbs	pbs	PROPN
ctmj-188	94	16	before	before	ADP
ctmj-188	94	17	each	each	DET
ctmj-188	94	18	reagent	reagent	ADJ
ctmj-188	94	19	change	change	NOUN
ctmj-188	94	20	.	.	PUNCT
ctmj-188	95	1	finally	finally	ADV
ctmj-188	95	2	,	,	PUNCT
ctmj-188	95	3	the	the	DET
ctmj-188	95	4	sections	section	NOUN
ctmj-188	95	5	were	be	AUX
ctmj-188	95	6	stained	stain	VERB
ctmj-188	95	7	using	use	VERB
ctmj-188	95	8	a	a	DET
ctmj-188	95	9	dab	dab	NOUN
ctmj-188	95	10	kit	kit	NOUN
ctmj-188	95	11	(	(	PUNCT
ctmj-188	95	12	dab-0031	dab-0031	NOUN
ctmj-188	95	13	,	,	PUNCT
ctmj-188	95	14	solarbio	solarbio	NOUN
ctmj-188	95	15	,	,	PUNCT
ctmj-188	95	16	china	china	PROPN
ctmj-188	95	17	)	)	PUNCT
ctmj-188	95	18	and	and	CCONJ
ctmj-188	95	19	hematoxylin	hematoxylin	NOUN
ctmj-188	95	20	was	be	AUX
ctmj-188	95	21	used	use	VERB
ctmj-188	95	22	for	for	ADP
ctmj-188	95	23	restaining	restaine	VERB
ctmj-188	95	24	for	for	ADP
ctmj-188	95	25	1	1	NUM
ctmj-188	95	26	min	min	NOUN
ctmj-188	95	27	(	(	PUNCT
ctmj-188	95	28	g1140	g1140	NOUN
ctmj-188	95	29	,	,	PUNCT
ctmj-188	95	30	solarbio	solarbio	NOUN
ctmj-188	95	31	,	,	PUNCT
ctmj-188	95	32	china	china	PROPN
ctmj-188	95	33	)	)	PUNCT
ctmj-188	95	34	.	.	PUNCT
ctmj-188	96	1	five	five	NUM
ctmj-188	96	2	random	random	ADJ
ctmj-188	96	3	fields	field	NOUN
ctmj-188	96	4	from	from	ADP
ctmj-188	96	5	each	each	DET
ctmj-188	96	6	slice	slice	NOUN
ctmj-188	96	7	were	be	AUX
ctmj-188	96	8	imaged	image	VERB
ctmj-188	96	9	at	at	ADP
ctmj-188	96	10	×400	×400	ADJ
ctmj-188	96	11	magnification	magnification	NOUN
ctmj-188	96	12	.	.	PUNCT
ctmj-188	97	1	the	the	DET
ctmj-188	97	2	positive	positive	ADJ
ctmj-188	97	3	expression	expression	NOUN
ctmj-188	97	4	in	in	ADP
ctmj-188	97	5	tumor	tumor	NOUN
ctmj-188	97	6	tissues	tissue	NOUN
ctmj-188	97	7	was	be	AUX
ctmj-188	97	8	quantified	quantify	VERB
ctmj-188	97	9	using	use	VERB
ctmj-188	97	10	a	a	DET
ctmj-188	97	11	true	true	ADJ
ctmj-188	97	12	-	-	PUNCT
ctmj-188	97	13	color	color	NOUN
ctmj-188	97	14	multifunctional	multifunctional	ADJ
ctmj-188	97	15	cellular	cellular	ADJ
ctmj-188	97	16	image	image	NOUN
ctmj-188	97	17	analysis	analysis	NOUN
ctmj-188	97	18	system	system	NOUN
ctmj-188	97	19	(	(	PUNCT
ctmj-188	97	20	image‑pro	image‑pro	PROPN
ctmj-188	97	21	plus	plus	NOUN
ctmj-188	97	22	,	,	PUNCT
ctmj-188	97	23	media	medium	NOUN
ctmj-188	97	24	cybernetics	cybernetic	NOUN
ctmj-188	97	25	)	)	PUNCT
ctmj-188	97	26	.	.	PUNCT
ctmj-188	98	1	tunel	tunel	PROPN
ctmj-188	98	2	staining	stain	VERB
ctmj-188	98	3	the	the	DET
ctmj-188	98	4	tumor	tumor	NOUN
ctmj-188	98	5	tissues	tissue	NOUN
ctmj-188	98	6	,	,	PUNCT
ctmj-188	98	7	fixed	fix	VERB
ctmj-188	98	8	with	with	ADP
ctmj-188	98	9	4	4	NUM
ctmj-188	98	10	%	%	NOUN
ctmj-188	98	11	paraformaldehyde	paraformaldehyde	NOUN
ctmj-188	98	12	,	,	PUNCT
ctmj-188	98	13	were	be	AUX
ctmj-188	98	14	treated	treat	VERB
ctmj-188	98	15	with	with	ADP
ctmj-188	98	16	triton	triton	PROPN
ctmj-188	98	17	x-100	x-100	PROPN
ctmj-188	98	18	,	,	PUNCT
ctmj-188	98	19	and	and	CCONJ
ctmj-188	98	20	then	then	ADV
ctmj-188	98	21	sealed	seal	VERB
ctmj-188	98	22	with	with	ADP
ctmj-188	98	23	goat	goat	PROPN
ctmj-188	98	24	serum	serum	PROPN
ctmj-188	98	25	.	.	PUNCT
ctmj-188	99	1	they	they	PRON
ctmj-188	99	2	were	be	AUX
ctmj-188	99	3	subsequently	subsequently	ADV
ctmj-188	99	4	incubated	incubate	VERB
ctmj-188	99	5	with	with	ADP
ctmj-188	99	6	tunel	tunel	NOUN
ctmj-188	99	7	immunofluorescence	immunofluorescence	NOUN
ctmj-188	99	8	reagent	reagent	NOUN
ctmj-188	99	9	.	.	PUNCT
ctmj-188	100	1	after	after	SCONJ
ctmj-188	100	2	stained	stain	VERB
ctmj-188	100	3	with	with	ADP
ctmj-188	100	4	dapi	dapi	PROPN
ctmj-188	100	5	,	,	PUNCT
ctmj-188	100	6	the	the	DET
ctmj-188	100	7	tissues	tissue	NOUN
ctmj-188	100	8	were	be	AUX
ctmj-188	100	9	photografted	photografte	VERB
ctmj-188	100	10	using	use	VERB
ctmj-188	100	11	a	a	DET
ctmj-188	100	12	confocal	confocal	ADJ
ctmj-188	100	13	laser	laser	NOUN
ctmj-188	100	14	scanning	scan	VERB
ctmj-188	100	15	microscope	microscope	NOUN
ctmj-188	100	16	(	(	PUNCT
ctmj-188	100	17	zeiss	zeiss	PROPN
ctmj-188	100	18	,	,	PUNCT
ctmj-188	100	19	germany	germany	PROPN
ctmj-188	100	20	)	)	PUNCT
ctmj-188	100	21	.	.	PUNCT
ctmj-188	101	1	optimal	optimal	ADJ
ctmj-188	101	2	time	time	NOUN
ctmj-188	101	3	for	for	ADP
ctmj-188	101	4	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	101	5	3‑kinase	3‑kinase	NUM
ctmj-188	101	6	/	/	SYM
ctmj-188	101	7	protein	protein	NOUN
ctmj-188	101	8	kinase	kinase	PROPN
ctmj-188	101	9	b	b	PROPN
ctmj-188	101	10	pathway	pathway	NOUN
ctmj-188	101	11	activation	activation	NOUN
ctmj-188	101	12	after	after	ADP
ctmj-188	101	13	10	10	NUM
ctmj-188	101	14	h	h	NOUN
ctmj-188	101	15	’	'	PUNCT
ctmj-188	101	16	culture	culture	NOUN
ctmj-188	101	17	,	,	PUNCT
ctmj-188	101	18	hct‑8	hct‑8	NOUN
ctmj-188	101	19	cells	cell	NOUN
ctmj-188	101	20	were	be	AUX
ctmj-188	101	21	changed	change	VERB
ctmj-188	101	22	into	into	ADP
ctmj-188	101	23	rpmi	rpmi	NOUN
ctmj-188	101	24	1640	1640	NUM
ctmj-188	101	25	blank	blank	ADJ
ctmj-188	101	26	medium	medium	NOUN
ctmj-188	101	27	for	for	ADP
ctmj-188	101	28	24	24	NUM
ctmj-188	101	29	h.	h.	PROPN
ctmj-188	101	30	subsequently	subsequently	ADV
ctmj-188	101	31	,	,	PUNCT
ctmj-188	101	32	10	10	NUM
ctmj-188	101	33	%	%	NOUN
ctmj-188	101	34	fbs	fbs	PROPN
ctmj-188	101	35	was	be	AUX
ctmj-188	101	36	added	add	VERB
ctmj-188	101	37	at	at	ADP
ctmj-188	101	38	0	0	NUM
ctmj-188	101	39	,	,	PUNCT
ctmj-188	101	40	5	5	NUM
ctmj-188	101	41	,	,	PUNCT
ctmj-188	101	42	15	15	NUM
ctmj-188	101	43	,	,	PUNCT
ctmj-188	101	44	30	30	NUM
ctmj-188	101	45	,	,	PUNCT
ctmj-188	101	46	60	60	NUM
ctmj-188	101	47	and	and	CCONJ
ctmj-188	101	48	120	120	NUM
ctmj-188	101	49	min	min	NOUN
ctmj-188	101	50	,	,	PUNCT
ctmj-188	101	51	respectively	respectively	ADV
ctmj-188	101	52	,	,	PUNCT
ctmj-188	101	53	then	then	ADV
ctmj-188	101	54	p‑akt	p‑akt	INTJ
ctmj-188	101	55	was	be	AUX
ctmj-188	101	56	analyzed	analyze	VERB
ctmj-188	101	57	by	by	ADP
ctmj-188	101	58	western	western	ADJ
ctmj-188	101	59	blot	blot	NOUN
ctmj-188	101	60	.	.	PUNCT
ctmj-188	102	1	47	47	NUM
ctmj-188	102	2	ctmj	ctmj	NOUN
ctmj-188	102	3	|	|	ADV
ctmj-188	102	4	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	102	5	chinese	chinese	ADJ
ctmj-188	102	6	traditional	traditional	ADJ
ctmj-188	102	7	medicine	medicine	NOUN
ctmj-188	102	8	journal	journal	NOUN
ctmj-188	102	9	|	|	ADV
ctmj-188	102	10	2025	2025	NUM
ctmj-188	102	11	|	|	ADV
ctmj-188	102	12	vol	vol	NOUN
ctmj-188	102	13	8	8	NUM
ctmj-188	102	14	|issue	|issue	NOUN
ctmj-188	102	15	1	1	NUM
ctmj-188	102	16	47	47	NUM
ctmj-188	102	17	the	the	DET
ctmj-188	102	18	combined	combine	VERB
ctmj-188	102	19	effect	effect	NOUN
ctmj-188	102	20	of	of	ADP
ctmj-188	102	21	qingjie	qingjie	NOUN
ctmj-188	102	22	fuzheng	fuzheng	PROPN
ctmj-188	102	23	granule	granule	PROPN
ctmj-188	102	24	and	and	CCONJ
ctmj-188	102	25	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	102	26	on	on	ADP
ctmj-188	102	27	survival	survival	NOUN
ctmj-188	102	28	,	,	PUNCT
ctmj-188	102	29	apoptosis	apoptosis	NOUN
ctmj-188	102	30	,	,	PUNCT
ctmj-188	102	31	migration	migration	NOUN
ctmj-188	102	32	,	,	PUNCT
ctmj-188	102	33	and	and	CCONJ
ctmj-188	102	34	invasion	invasion	NOUN
ctmj-188	102	35	of	of	ADP
ctmj-188	102	36	hct‑8	hct‑8	NOUN
ctmj-188	102	37	cells	cell	NOUN
ctmj-188	102	38	after	after	ADP
ctmj-188	102	39	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	102	40	3‑kinase	3‑kinase	NOUN
ctmj-188	102	41	/	/	SYM
ctmj-188	102	42	protein	protein	NOUN
ctmj-188	102	43	kinase	kinase	PROPN
ctmj-188	102	44	b	b	PROPN
ctmj-188	102	45	pathway	pathway	NOUN
ctmj-188	102	46	activation	activation	NOUN
ctmj-188	102	47	hct-8	hct-8	PUNCT
ctmj-188	102	48	cells	cell	NOUN
ctmj-188	102	49	were	be	AUX
ctmj-188	102	50	pretreated	pretreate	VERB
ctmj-188	102	51	for	for	ADP
ctmj-188	102	52	24	24	NUM
ctmj-188	102	53	h	h	NOUN
ctmj-188	102	54	,	,	PUNCT
ctmj-188	102	55	followed	follow	VERB
ctmj-188	102	56	by	by	ADP
ctmj-188	102	57	a	a	DET
ctmj-188	102	58	30	30	NUM
ctmj-188	102	59	-	-	PUNCT
ctmj-188	102	60	min	min	NOUN
ctmj-188	102	61	culture	culture	NOUN
ctmj-188	102	62	to	to	PART
ctmj-188	102	63	activate	activate	VERB
ctmj-188	102	64	pi3k	pi3k	PROPN
ctmj-188	102	65	/	/	SYM
ctmj-188	102	66	akt	akt	PROPN
ctmj-188	102	67	pathway	pathway	NOUN
ctmj-188	102	68	.	.	PUNCT
ctmj-188	103	1	subsequently	subsequently	ADV
ctmj-188	103	2	,	,	PUNCT
ctmj-188	103	3	morphological	morphological	ADJ
ctmj-188	103	4	observation	observation	NOUN
ctmj-188	103	5	,	,	PUNCT
ctmj-188	103	6	colony	colony	NOUN
ctmj-188	103	7	formation	formation	NOUN
ctmj-188	103	8	,	,	PUNCT
ctmj-188	103	9	dapi	dapi	ADJ
ctmj-188	103	10	staining	staining	NOUN
ctmj-188	103	11	,	,	PUNCT
ctmj-188	103	12	migration	migration	NOUN
ctmj-188	103	13	,	,	PUNCT
ctmj-188	103	14	and	and	CCONJ
ctmj-188	103	15	invasion	invasion	NOUN
ctmj-188	103	16	assays	assay	NOUN
ctmj-188	103	17	were	be	AUX
ctmj-188	103	18	performed	perform	VERB
ctmj-188	103	19	.	.	PUNCT
ctmj-188	104	1	statistical	statistical	ADJ
ctmj-188	104	2	analysis	analysis	NOUN
ctmj-188	104	3	the	the	DET
ctmj-188	104	4	data	datum	NOUN
ctmj-188	104	5	are	be	AUX
ctmj-188	104	6	presented	present	VERB
ctmj-188	104	7	as	as	ADP
ctmj-188	104	8	mean	mean	NOUN
ctmj-188	104	9	±	±	NUM
ctmj-188	104	10	standard	standard	ADJ
ctmj-188	104	11	deviation	deviation	NOUN
ctmj-188	104	12	,	,	PUNCT
ctmj-188	104	13	and	and	CCONJ
ctmj-188	104	14	statistical	statistical	ADJ
ctmj-188	104	15	analyses	analysis	NOUN
ctmj-188	104	16	were	be	AUX
ctmj-188	104	17	performed	perform	VERB
ctmj-188	104	18	using	use	VERB
ctmj-188	104	19	graphpad	graphpad	NOUN
ctmj-188	104	20	prism	prism	NOUN
ctmj-188	104	21	(	(	PUNCT
ctmj-188	104	22	version	version	NOUN
ctmj-188	104	23	8.2.1	8.2.1	NUM
ctmj-188	104	24	windows	window	NOUN
ctmj-188	104	25	version	version	NOUN
ctmj-188	104	26	,	,	PUNCT
ctmj-188	104	27	graphpad	graphpad	NOUN
ctmj-188	104	28	software	software	NOUN
ctmj-188	104	29	,	,	PUNCT
ctmj-188	104	30	san	san	PROPN
ctmj-188	104	31	diego	diego	PROPN
ctmj-188	104	32	)	)	PUNCT
ctmj-188	104	33	.	.	PUNCT
ctmj-188	105	1	the	the	DET
ctmj-188	105	2	unpaired	unpaired	ADJ
ctmj-188	105	3	student	student	NOUN
ctmj-188	105	4	’s	’s	PART
ctmj-188	105	5	t	t	PROPN
ctmj-188	105	6	-	-	PUNCT
ctmj-188	105	7	test	test	NOUN
ctmj-188	105	8	was	be	AUX
ctmj-188	105	9	applied	apply	VERB
ctmj-188	105	10	to	to	PART
ctmj-188	105	11	compare	compare	VERB
ctmj-188	105	12	two	two	NUM
ctmj-188	105	13	groups	group	NOUN
ctmj-188	105	14	,	,	PUNCT
ctmj-188	105	15	and	and	CCONJ
ctmj-188	105	16	one	one	NUM
ctmj-188	105	17	-	-	PUNCT
ctmj-188	105	18	way	way	NOUN
ctmj-188	105	19	analysis	analysis	NOUN
ctmj-188	105	20	of	of	ADP
ctmj-188	105	21	variance	variance	NOUN
ctmj-188	105	22	,	,	PUNCT
ctmj-188	105	23	followed	follow	VERB
ctmj-188	105	24	by	by	ADP
ctmj-188	105	25	post	post	PROPN
ctmj-188	105	26	hoc	hoc	X
ctmj-188	105	27	fisher	fisher	PROPN
ctmj-188	105	28	’s	’s	PART
ctmj-188	105	29	least	least	ADJ
ctmj-188	105	30	significant	significant	ADJ
ctmj-188	105	31	difference	difference	NOUN
ctmj-188	105	32	testing	testing	NOUN
ctmj-188	105	33	was	be	AUX
ctmj-188	105	34	applied	apply	VERB
ctmj-188	105	35	to	to	PART
ctmj-188	105	36	compare	compare	VERB
ctmj-188	105	37	multiple	multiple	ADJ
ctmj-188	105	38	groups	group	NOUN
ctmj-188	105	39	.	.	PUNCT
ctmj-188	106	1	p	p	X
ctmj-188	106	2	<	<	X
ctmj-188	106	3	0.05	0.05	NUM
ctmj-188	106	4	was	be	AUX
ctmj-188	106	5	considered	consider	VERB
ctmj-188	106	6	statistically	statistically	ADV
ctmj-188	106	7	significant	significant	ADJ
ctmj-188	106	8	.	.	PUNCT
ctmj-188	107	1	results	result	VERB
ctmj-188	107	2	synergistic	synergistic	ADJ
ctmj-188	107	3	effects	effect	NOUN
ctmj-188	107	4	of	of	ADP
ctmj-188	107	5	qingjie	qingjie	NOUN
ctmj-188	107	6	fuzheng	fuzheng	PROPN
ctmj-188	107	7	granule	granule	PROPN
ctmj-188	107	8	and	and	CCONJ
ctmj-188	107	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	107	10	in	in	ADP
ctmj-188	107	11	colorectal	colorectal	ADJ
ctmj-188	107	12	cancer	cancer	NOUN
ctmj-188	107	13	cells	cell	NOUN
ctmj-188	107	14	treatment	treatment	NOUN
ctmj-188	107	15	with	with	ADP
ctmj-188	107	16	qfg	qfg	NOUN
ctmj-188	107	17	and	and	CCONJ
ctmj-188	107	18	5‑fu	5‑fu	PROPN
ctmj-188	107	19	for	for	ADP
ctmj-188	107	20	24	24	NUM
ctmj-188	107	21	h	h	NOUN
ctmj-188	107	22	or	or	CCONJ
ctmj-188	107	23	48	48	NUM
ctmj-188	107	24	h	h	NOUN
ctmj-188	107	25	,	,	PUNCT
ctmj-188	107	26	chou‑talalay	chou‑talalay	PROPN
ctmj-188	107	27	was	be	AUX
ctmj-188	107	28	used	use	VERB
ctmj-188	107	29	to	to	PART
ctmj-188	107	30	calculate	calculate	VERB
ctmj-188	107	31	the	the	DET
ctmj-188	107	32	ci	ci	NOUN
ctmj-188	107	33	.	.	PROPN
ctmj-188	108	1	as	as	SCONJ
ctmj-188	108	2	shown	show	VERB
ctmj-188	108	3	in	in	ADP
ctmj-188	108	4	figure	figure	NOUN
ctmj-188	108	5	1	1	NUM
ctmj-188	108	6	,	,	PUNCT
ctmj-188	108	7	the	the	DET
ctmj-188	108	8	ci	ci	NOUN
ctmj-188	108	9	values	value	NOUN
ctmj-188	108	10	were	be	AUX
ctmj-188	108	11	all	all	PRON
ctmj-188	108	12	<	<	X
ctmj-188	108	13	1	1	NUM
ctmj-188	108	14	,	,	PUNCT
ctmj-188	108	15	that	that	PRON
ctmj-188	108	16	indicated	indicate	VERB
ctmj-188	108	17	a	a	DET
ctmj-188	108	18	synergistic	synergistic	ADJ
ctmj-188	108	19	anti	anti	ADJ
ctmj-188	108	20	-	-	ADJ
ctmj-188	108	21	cancer	cancer	ADJ
ctmj-188	108	22	effect	effect	NOUN
ctmj-188	108	23	of	of	ADP
ctmj-188	108	24	qfg	qfg	NOUN
ctmj-188	108	25	and	and	CCONJ
ctmj-188	108	26	5‑fu	5‑fu	PROPN
ctmj-188	108	27	.	.	PUNCT
ctmj-188	109	1	the	the	DET
ctmj-188	109	2	synergistic	synergistic	ADJ
ctmj-188	109	3	effect	effect	NOUN
ctmj-188	109	4	was	be	AUX
ctmj-188	109	5	more	more	ADV
ctmj-188	109	6	significant	significant	ADJ
ctmj-188	109	7	in	in	ADP
ctmj-188	109	8	hct‑8	hct‑8	NOUN
ctmj-188	109	9	cells	cell	NOUN
ctmj-188	109	10	.	.	PUNCT
ctmj-188	110	1	the	the	DET
ctmj-188	110	2	synergistic	synergistic	ADJ
ctmj-188	110	3	effect	effect	NOUN
ctmj-188	110	4	of	of	ADP
ctmj-188	110	5	qfg/5‑fu	qfg/5‑fu	PROPN
ctmj-188	110	6	at	at	ADP
ctmj-188	110	7	a	a	DET
ctmj-188	110	8	ratio	ratio	NOUN
ctmj-188	110	9	of	of	ADP
ctmj-188	110	10	80:1	80:1	NUM
ctmj-188	110	11	was	be	AUX
ctmj-188	110	12	stronger	strong	ADJ
ctmj-188	110	13	in	in	ADP
ctmj-188	110	14	crc	crc	NOUN
ctmj-188	110	15	hct-8	hct-8	PART
ctmj-188	110	16	cells	cell	NOUN
ctmj-188	110	17	.	.	PUNCT
ctmj-188	111	1	therefore	therefore	ADV
ctmj-188	111	2	,	,	PUNCT
ctmj-188	111	3	the	the	DET
ctmj-188	111	4	best	good	ADJ
ctmj-188	111	5	concentrations	concentration	NOUN
ctmj-188	111	6	of	of	ADP
ctmj-188	111	7	qfg	qfg	NOUN
ctmj-188	111	8	and	and	CCONJ
ctmj-188	111	9	5‑fu	5‑fu	PROPN
ctmj-188	111	10	were	be	AUX
ctmj-188	111	11	0.25	0.25	NUM
ctmj-188	111	12	mg	mg	PROPN
ctmj-188	111	13	/	/	SYM
ctmj-188	111	14	ml	ml	NOUN
ctmj-188	111	15	and	and	CCONJ
ctmj-188	111	16	3.13	3.13	NUM
ctmj-188	111	17	×	×	NOUN
ctmj-188	111	18	10−3	10−3	NUM
ctmj-188	111	19	mg	mg	NUM
ctmj-188	111	20	/	/	SYM
ctmj-188	111	21	ml	ml	X
ctmj-188	111	22	respectively	respectively	ADV
ctmj-188	111	23	,	,	PUNCT
ctmj-188	111	24	in	in	ADP
ctmj-188	111	25	hct-8	hct-8	PUNCT
ctmj-188	111	26	cells	cell	NOUN
ctmj-188	111	27	.	.	PUNCT
ctmj-188	112	1	qingjie	qingjie	PROPN
ctmj-188	112	2	fuzheng	fuzheng	PROPN
ctmj-188	112	3	granule	granule	PROPN
ctmj-188	112	4	combined	combine	VERB
ctmj-188	112	5	with	with	ADP
ctmj-188	112	6	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	112	7	synergistically	synergistically	ADV
ctmj-188	112	8	inhibited	inhibit	VERB
ctmj-188	112	9	intestinal	intestinal	ADJ
ctmj-188	112	10	cancer	cancer	NOUN
ctmj-188	112	11	growth	growth	NOUN
ctmj-188	112	12	the	the	DET
ctmj-188	112	13	synergistic	synergistic	ADJ
ctmj-188	112	14	activity	activity	NOUN
ctmj-188	112	15	of	of	ADP
ctmj-188	112	16	qfg	qfg	NOUN
ctmj-188	112	17	combined	combine	VERB
ctmj-188	112	18	with	with	ADP
ctmj-188	112	19	5‑fu	5‑fu	PROPN
ctmj-188	112	20	on	on	ADP
ctmj-188	112	21	hct-8	hct-8	PUNCT
ctmj-188	112	22	cells	cell	NOUN
ctmj-188	112	23	was	be	AUX
ctmj-188	112	24	assesses	assesse	NOUN
ctmj-188	112	25	in	in	ADP
ctmj-188	112	26	vitro	vitro	X
ctmj-188	112	27	and	and	CCONJ
ctmj-188	112	28	in	in	ADP
ctmj-188	112	29	vivo	vivo	NOUN
ctmj-188	112	30	.	.	PUNCT
ctmj-188	113	1	as	as	SCONJ
ctmj-188	113	2	shown	show	VERB
ctmj-188	113	3	in	in	ADP
ctmj-188	113	4	figure	figure	NOUN
ctmj-188	113	5	2a	2a	NUM
ctmj-188	113	6	,	,	PUNCT
ctmj-188	113	7	treatment	treatment	NOUN
ctmj-188	113	8	with	with	ADP
ctmj-188	113	9	qfg	qfg	NOUN
ctmj-188	113	10	and	and	CCONJ
ctmj-188	113	11	5‑fu	5‑fu	PROPN
ctmj-188	113	12	significantly	significantly	ADV
ctmj-188	113	13	reduced	reduce	VERB
ctmj-188	113	14	the	the	DET
ctmj-188	113	15	viability	viability	NOUN
ctmj-188	113	16	of	of	ADP
ctmj-188	113	17	hct-8	hct-8	PUNCT
ctmj-188	113	18	cells	cell	NOUN
ctmj-188	113	19	in	in	ADP
ctmj-188	113	20	a	a	DET
ctmj-188	113	21	time	time	NOUN
ctmj-188	113	22	-	-	PUNCT
ctmj-188	113	23	dependent	dependent	ADJ
ctmj-188	113	24	manner	manner	NOUN
ctmj-188	113	25	(	(	PUNCT
ctmj-188	113	26	p	p	X
ctmj-188	113	27	<	<	X
ctmj-188	113	28	0.05	0.05	NUM
ctmj-188	113	29	)	)	PUNCT
ctmj-188	113	30	.	.	PUNCT
ctmj-188	114	1	furthermore	furthermore	ADV
ctmj-188	114	2	,	,	PUNCT
ctmj-188	114	3	the	the	DET
ctmj-188	114	4	combination	combination	NOUN
ctmj-188	114	5	of	of	ADP
ctmj-188	114	6	qfg	qfg	NOUN
ctmj-188	114	7	and	and	CCONJ
ctmj-188	114	8	5‑fu	5‑fu	NUM
ctmj-188	114	9	induced	induce	VERB
ctmj-188	114	10	to	to	ADP
ctmj-188	114	11	a	a	DET
ctmj-188	114	12	decrease	decrease	NOUN
ctmj-188	114	13	in	in	ADP
ctmj-188	114	14	the	the	DET
ctmj-188	114	15	number	number	NOUN
ctmj-188	114	16	of	of	ADP
ctmj-188	114	17	attached	attached	ADJ
ctmj-188	114	18	and	and	CCONJ
ctmj-188	114	19	detached	detach	VERB
ctmj-188	114	20	hct-8	hct-8	PUNCT
ctmj-188	114	21	cells	cell	NOUN
ctmj-188	114	22	after	after	ADP
ctmj-188	114	23	24	24	NUM
ctmj-188	114	24	h	h	NOUN
ctmj-188	115	1	[	[	X
ctmj-188	115	2	figure	figure	NOUN
ctmj-188	115	3	2b	2b	NOUN
ctmj-188	115	4	]	]	PUNCT
ctmj-188	115	5	.	.	PUNCT
ctmj-188	116	1	moreover	moreover	ADV
ctmj-188	116	2	,	,	PUNCT
ctmj-188	116	3	we	we	PRON
ctmj-188	116	4	explored	explore	VERB
ctmj-188	116	5	the	the	DET
ctmj-188	116	6	synergistic	synergistic	ADJ
ctmj-188	116	7	effect	effect	NOUN
ctmj-188	116	8	of	of	ADP
ctmj-188	116	9	qfg	qfg	NOUN
ctmj-188	116	10	and	and	CCONJ
ctmj-188	116	11	5‑fu	5‑fu	PROPN
ctmj-188	116	12	using	use	VERB
ctmj-188	116	13	xenograft	xenograft	NOUN
ctmj-188	116	14	mice	mouse	NOUN
ctmj-188	116	15	,	,	PUNCT
ctmj-188	116	16	as	as	SCONJ
ctmj-188	116	17	shown	show	VERB
ctmj-188	116	18	in	in	ADP
ctmj-188	116	19	figure	figure	NOUN
ctmj-188	116	20	2c	2c	NOUN
ctmj-188	116	21	and	and	CCONJ
ctmj-188	116	22	d	d	NOUN
ctmj-188	116	23	,	,	PUNCT
ctmj-188	116	24	compared	compare	VERB
ctmj-188	116	25	with	with	ADP
ctmj-188	116	26	treatment	treatment	NOUN
ctmj-188	116	27	with	with	ADP
ctmj-188	116	28	qfg	qfg	NOUN
ctmj-188	116	29	or	or	CCONJ
ctmj-188	116	30	5‑fu	5‑fu	PROPN
ctmj-188	116	31	alone	alone	ADV
ctmj-188	116	32	,	,	PUNCT
ctmj-188	116	33	the	the	DET
ctmj-188	116	34	combination	combination	NOUN
ctmj-188	116	35	significantly	significantly	ADV
ctmj-188	116	36	inhibited	inhibit	VERB
ctmj-188	116	37	the	the	DET
ctmj-188	116	38	tumor	tumor	NOUN
ctmj-188	116	39	volume	volume	NOUN
ctmj-188	116	40	(	(	PUNCT
ctmj-188	116	41	p	p	X
ctmj-188	116	42	<	<	X
ctmj-188	116	43	0.05	0.05	NUM
ctmj-188	116	44	)	)	PUNCT
ctmj-188	116	45	.	.	PUNCT
ctmj-188	117	1	in	in	ADP
ctmj-188	117	2	addition	addition	NOUN
ctmj-188	117	3	,	,	PUNCT
ctmj-188	117	4	the	the	DET
ctmj-188	117	5	combination	combination	NOUN
ctmj-188	117	6	of	of	ADP
ctmj-188	117	7	qfg	qfg	NOUN
ctmj-188	117	8	and	and	CCONJ
ctmj-188	117	9	5‑fu	5‑fu	PROPN
ctmj-188	117	10	resulted	result	VERB
ctmj-188	117	11	in	in	ADP
ctmj-188	117	12	a	a	DET
ctmj-188	117	13	reduction	reduction	NOUN
ctmj-188	117	14	in	in	ADP
ctmj-188	117	15	tumor	tumor	NOUN
ctmj-188	117	16	weight	weight	NOUN
ctmj-188	117	17	as	as	SCONJ
ctmj-188	117	18	shown	show	VERB
ctmj-188	117	19	in	in	ADP
ctmj-188	117	20	figure	figure	NOUN
ctmj-188	117	21	2e	2e	NOUN
ctmj-188	117	22	(	(	PUNCT
ctmj-188	117	23	p	p	X
ctmj-188	117	24	<	<	X
ctmj-188	117	25	0.05	0.05	NUM
ctmj-188	117	26	)	)	PUNCT
ctmj-188	117	27	.	.	PUNCT
ctmj-188	118	1	taken	take	VERB
ctmj-188	118	2	together	together	ADV
ctmj-188	118	3	,	,	PUNCT
ctmj-188	118	4	these	these	DET
ctmj-188	118	5	data	datum	NOUN
ctmj-188	118	6	suggest	suggest	VERB
ctmj-188	118	7	that	that	SCONJ
ctmj-188	118	8	qfg	qfg	NOUN
ctmj-188	118	9	combined	combine	VERB
ctmj-188	118	10	with	with	ADP
ctmj-188	118	11	5‑fu	5‑fu	PROPN
ctmj-188	118	12	effectively	effectively	ADV
ctmj-188	118	13	synergizes	synergize	VERB
ctmj-188	118	14	to	to	PART
ctmj-188	118	15	inhibit	inhibit	VERB
ctmj-188	118	16	the	the	DET
ctmj-188	118	17	growth	growth	NOUN
ctmj-188	118	18	of	of	ADP
ctmj-188	118	19	intestinal	intestinal	ADJ
ctmj-188	118	20	cancer	cancer	NOUN
ctmj-188	118	21	both	both	CCONJ
ctmj-188	118	22	in	in	ADP
ctmj-188	118	23	vitro	vitro	X
ctmj-188	118	24	and	and	CCONJ
ctmj-188	118	25	in	in	ADP
ctmj-188	118	26	vivo	vivo	NOUN
ctmj-188	118	27	.	.	PUNCT
ctmj-188	119	1	qingjie	qingjie	PROPN
ctmj-188	119	2	fuzheng	fuzheng	PROPN
ctmj-188	119	3	granule	granule	PROPN
ctmj-188	119	4	and	and	CCONJ
ctmj-188	119	5	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	119	6	synergisticly	synergisticly	ADV
ctmj-188	119	7	inhibited	inhibit	VERB
ctmj-188	119	8	the	the	DET
ctmj-188	119	9	proliferation	proliferation	NOUN
ctmj-188	119	10	of	of	ADP
ctmj-188	119	11	hct‑8	hct‑8	NOUN
ctmj-188	119	12	cells	cell	NOUN
ctmj-188	119	13	to	to	PART
ctmj-188	119	14	investigate	investigate	VERB
ctmj-188	119	15	the	the	DET
ctmj-188	119	16	effects	effect	NOUN
ctmj-188	119	17	of	of	ADP
ctmj-188	119	18	qfg	qfg	NOUN
ctmj-188	119	19	combined	combine	VERB
ctmj-188	119	20	with	with	ADP
ctmj-188	119	21	5‑fu	5‑fu	PROPN
ctmj-188	119	22	on	on	ADP
ctmj-188	119	23	the	the	DET
ctmj-188	119	24	proliferation	proliferation	NOUN
ctmj-188	119	25	of	of	ADP
ctmj-188	119	26	hct-8	hct-8	PUNCT
ctmj-188	119	27	cells	cell	NOUN
ctmj-188	119	28	in	in	ADP
ctmj-188	119	29	vitro	vitro	X
ctmj-188	119	30	and	and	CCONJ
ctmj-188	119	31	in	in	ADP
ctmj-188	119	32	vivo	vivo	NOUN
ctmj-188	119	33	,	,	PUNCT
ctmj-188	119	34	colony	colony	NOUN
ctmj-188	119	35	formation	formation	NOUN
ctmj-188	119	36	assays	assay	NOUN
ctmj-188	119	37	and	and	CCONJ
ctmj-188	119	38	immunohistochemical	immunohistochemical	ADJ
ctmj-188	119	39	staining	staining	NOUN
ctmj-188	119	40	were	be	AUX
ctmj-188	119	41	performed	perform	VERB
ctmj-188	119	42	.	.	PUNCT
ctmj-188	120	1	as	as	SCONJ
ctmj-188	120	2	shown	show	VERB
ctmj-188	120	3	in	in	ADP
ctmj-188	120	4	[	[	PUNCT
ctmj-188	120	5	figures	figure	NOUN
ctmj-188	120	6	3a	3a	NUM
ctmj-188	120	7	and	and	CCONJ
ctmj-188	120	8	b	b	NOUN
ctmj-188	120	9	]	]	X
ctmj-188	120	10	,	,	PUNCT
ctmj-188	120	11	qfg	qfg	NOUN
ctmj-188	120	12	combined	combine	VERB
ctmj-188	120	13	with	with	ADP
ctmj-188	120	14	5	5	NUM
ctmj-188	120	15	fu	fu	NOUN
ctmj-188	120	16	inhibited	inhibit	VERB
ctmj-188	120	17	the	the	DET
ctmj-188	120	18	ability	ability	NOUN
ctmj-188	120	19	of	of	ADP
ctmj-188	120	20	clonal	clonal	ADJ
ctmj-188	120	21	goblet	goblet	NOUN
ctmj-188	120	22	formation	formation	NOUN
ctmj-188	120	23	compared	compare	VERB
ctmj-188	120	24	with	with	ADP
ctmj-188	120	25	single	single	ADJ
ctmj-188	120	26	drug	drug	NOUN
ctmj-188	120	27	intervention	intervention	NOUN
ctmj-188	120	28	(	(	PUNCT
ctmj-188	120	29	p	p	X
ctmj-188	120	30	<	<	X
ctmj-188	120	31	0.05	0.05	NUM
ctmj-188	120	32	)	)	PUNCT
ctmj-188	120	33	.	.	PUNCT
ctmj-188	121	1	similarly	similarly	ADV
ctmj-188	121	2	,	,	PUNCT
ctmj-188	121	3	qfg	qfg	NOUN
ctmj-188	121	4	combined	combine	VERB
ctmj-188	121	5	with	with	ADP
ctmj-188	121	6	5‑fu	5‑fu	NUM
ctmj-188	121	7	inhibited	inhibit	VERB
ctmj-188	121	8	ki‑67	ki‑67	ADJ
ctmj-188	121	9	expression	expression	NOUN
ctmj-188	121	10	in	in	ADP
ctmj-188	121	11	tumor	tumor	NOUN
ctmj-188	121	12	tissues	tissue	NOUN
ctmj-188	122	1	[	[	X
ctmj-188	122	2	figure	figure	NOUN
ctmj-188	122	3	3e	3e	NOUN
ctmj-188	122	4	and	and	CCONJ
ctmj-188	122	5	f	f	X
ctmj-188	122	6	]	]	X
ctmj-188	122	7	.	.	PUNCT
ctmj-188	123	1	moreover	moreover	ADV
ctmj-188	123	2	,	,	PUNCT
ctmj-188	123	3	as	as	SCONJ
ctmj-188	123	4	shown	show	VERB
ctmj-188	123	5	in	in	ADP
ctmj-188	123	6	figure	figure	NOUN
ctmj-188	123	7	3c	3c	NUM
ctmj-188	123	8	,	,	PUNCT
ctmj-188	123	9	d	d	PROPN
ctmj-188	123	10	,	,	PUNCT
ctmj-188	123	11	g	g	PROPN
ctmj-188	123	12	and	and	CCONJ
ctmj-188	123	13	h	h	NOUN
ctmj-188	123	14	,	,	PUNCT
ctmj-188	123	15	qfg	qfg	NOUN
ctmj-188	123	16	combined	combine	VERB
ctmj-188	123	17	with	with	ADP
ctmj-188	123	18	5‑fu	5‑fu	PROPN
ctmj-188	123	19	decreased	decrease	VERB
ctmj-188	123	20	cdk4	cdk4	NOUN
ctmj-188	123	21	and	and	CCONJ
ctmj-188	123	22	cyclin	cyclin	NOUN
ctmj-188	123	23	figure	figure	NOUN
ctmj-188	123	24	1	1	NUM
ctmj-188	123	25	:	:	PUNCT
ctmj-188	123	26	synergistic	synergistic	ADJ
ctmj-188	123	27	effects	effect	NOUN
ctmj-188	123	28	of	of	ADP
ctmj-188	123	29	qingjie	qingjie	NOUN
ctmj-188	123	30	fuzheng	fuzheng	PROPN
ctmj-188	123	31	granule	granule	PROPN
ctmj-188	123	32	(	(	PUNCT
ctmj-188	123	33	qfg	qfg	ADJ
ctmj-188	123	34	)	)	PUNCT
ctmj-188	123	35	and	and	CCONJ
ctmj-188	123	36	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	123	37	(	(	PUNCT
ctmj-188	123	38	5‑fu	5‑fu	PROPN
ctmj-188	123	39	)	)	PUNCT
ctmj-188	123	40	on	on	ADP
ctmj-188	123	41	colorectal	colorectal	ADJ
ctmj-188	123	42	cancer	cancer	NOUN
ctmj-188	123	43	.	.	PUNCT
ctmj-188	124	1	(	(	PUNCT
ctmj-188	124	2	a	a	X
ctmj-188	124	3	)	)	PUNCT
ctmj-188	124	4	24‑h	24‑h	NUM
ctmj-188	124	5	combination	combination	NOUN
ctmj-188	124	6	index	index	NOUN
ctmj-188	124	7	(	(	PUNCT
ctmj-188	124	8	ci	ci	NOUN
ctmj-188	124	9	)	)	PUNCT
ctmj-188	124	10	values	value	NOUN
ctmj-188	124	11	of	of	ADP
ctmj-188	124	12	different	different	ADJ
ctmj-188	124	13	ratios	ratio	NOUN
ctmj-188	124	14	of	of	ADP
ctmj-188	124	15	qfg	qfg	NOUN
ctmj-188	124	16	combined	combine	VERB
ctmj-188	124	17	with	with	ADP
ctmj-188	124	18	5‑fu	5‑fu	PROPN
ctmj-188	124	19	intervention	intervention	NOUN
ctmj-188	124	20	in	in	ADP
ctmj-188	124	21	hct‑8	hct‑8	NOUN
ctmj-188	124	22	cells	cell	NOUN
ctmj-188	124	23	.	.	PUNCT
ctmj-188	125	1	(	(	PUNCT
ctmj-188	125	2	b	b	X
ctmj-188	125	3	)	)	PUNCT
ctmj-188	125	4	48‑h	48‑h	NUM
ctmj-188	125	5	ci	ci	NOUN
ctmj-188	125	6	values	value	NOUN
ctmj-188	125	7	of	of	ADP
ctmj-188	125	8	different	different	ADJ
ctmj-188	125	9	ratios	ratio	NOUN
ctmj-188	125	10	of	of	ADP
ctmj-188	125	11	qfg	qfg	NOUN
ctmj-188	125	12	combined	combine	VERB
ctmj-188	125	13	with	with	ADP
ctmj-188	125	14	5‑fu	5‑fu	PROPN
ctmj-188	125	15	intervention	intervention	NOUN
ctmj-188	125	16	in	in	ADP
ctmj-188	125	17	hct‑8	hct‑8	NOUN
ctmj-188	125	18	cells	cell	NOUN
ctmj-188	125	19	.	.	PUNCT
ctmj-188	126	1	(	(	PUNCT
ctmj-188	126	2	c	c	X
ctmj-188	126	3	)	)	PUNCT
ctmj-188	126	4	24‑h	24‑h	NUM
ctmj-188	126	5	ci	ci	NOUN
ctmj-188	126	6	values	value	NOUN
ctmj-188	126	7	of	of	ADP
ctmj-188	126	8	different	different	ADJ
ctmj-188	126	9	ratios	ratio	NOUN
ctmj-188	126	10	of	of	ADP
ctmj-188	126	11	qfg	qfg	NOUN
ctmj-188	126	12	and	and	CCONJ
ctmj-188	126	13	5‑fu	5‑fu	PROPN
ctmj-188	126	14	intervention	intervention	NOUN
ctmj-188	126	15	in	in	ADP
ctmj-188	126	16	hct‑116	hct‑116	ADJ
ctmj-188	126	17	cells	cell	NOUN
ctmj-188	126	18	.	.	PUNCT
ctmj-188	127	1	(	(	PUNCT
ctmj-188	127	2	d	d	X
ctmj-188	127	3	)	)	PUNCT
ctmj-188	127	4	48‑h	48‑h	NUM
ctmj-188	127	5	ci	ci	NOUN
ctmj-188	127	6	values	value	NOUN
ctmj-188	127	7	of	of	ADP
ctmj-188	127	8	different	different	ADJ
ctmj-188	127	9	ratios	ratio	NOUN
ctmj-188	127	10	of	of	ADP
ctmj-188	127	11	qfg	qfg	NOUN
ctmj-188	127	12	combined	combine	VERB
ctmj-188	127	13	with	with	ADP
ctmj-188	127	14	5‑fu	5‑fu	PROPN
ctmj-188	127	15	intervention	intervention	NOUN
ctmj-188	127	16	in	in	ADP
ctmj-188	127	17	hct‑116	hct‑116	ADJ
ctmj-188	127	18	cells	cell	NOUN
ctmj-188	127	19	a	a	DET
ctmj-188	127	20	b	b	NOUN
ctmj-188	127	21	c	c	NOUN
ctmj-188	127	22	d	d	SYM
ctmj-188	127	23	48	48	NUM
ctmj-188	127	24	ctmj	ctmj	NOUN
ctmj-188	127	25	|	|	ADV
ctmj-188	127	26	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	127	27	chinese	chinese	ADJ
ctmj-188	127	28	traditional	traditional	ADJ
ctmj-188	127	29	medicine	medicine	NOUN
ctmj-188	127	30	journal	journal	NOUN
ctmj-188	127	31	|	|	ADV
ctmj-188	127	32	2025	2025	NUM
ctmj-188	127	33	|	|	ADV
ctmj-188	127	34	vol	vol	NOUN
ctmj-188	127	35	8	8	NUM
ctmj-188	127	36	|issue	|issue	NOUN
ctmj-188	127	37	1	1	NUM
ctmj-188	127	38	48	48	NUM
ctmj-188	127	39	figure	figure	NOUN
ctmj-188	127	40	2	2	NUM
ctmj-188	127	41	:	:	PUNCT
ctmj-188	127	42	synergistic	synergistic	ADJ
ctmj-188	127	43	inhibition	inhibition	NOUN
ctmj-188	127	44	of	of	ADP
ctmj-188	127	45	intestinal	intestinal	ADJ
ctmj-188	127	46	cancer	cancer	NOUN
ctmj-188	127	47	growth	growth	NOUN
ctmj-188	127	48	by	by	ADP
ctmj-188	127	49	qingjiefuzheng	qingjiefuzheng	PROPN
ctmj-188	127	50	granule	granule	PROPN
ctmj-188	127	51	(	(	PUNCT
ctmj-188	127	52	qfg	qfg	ADJ
ctmj-188	127	53	)	)	PUNCT
ctmj-188	127	54	and	and	CCONJ
ctmj-188	127	55	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	127	56	(	(	PUNCT
ctmj-188	127	57	5‑fu	5‑fu	PROPN
ctmj-188	127	58	)	)	PUNCT
ctmj-188	127	59	in	in	ADP
ctmj-188	127	60	vitro	vitro	X
ctmj-188	127	61	and	and	CCONJ
ctmj-188	127	62	in	in	ADP
ctmj-188	127	63	vivo	vivo	NOUN
ctmj-188	127	64	.	.	PUNCT
ctmj-188	128	1	(	(	PUNCT
ctmj-188	128	2	a	a	X
ctmj-188	128	3	)	)	PUNCT
ctmj-188	128	4	hct‑8	hct‑8	NOUN
ctmj-188	128	5	cells	cell	NOUN
ctmj-188	128	6	viability	viability	NOUN
ctmj-188	128	7	.	.	PUNCT
ctmj-188	129	1	(	(	PUNCT
ctmj-188	129	2	b	b	X
ctmj-188	129	3	)	)	PUNCT
ctmj-188	129	4	morphology	morphology	NOUN
ctmj-188	129	5	of	of	ADP
ctmj-188	129	6	hct‑8	hct‑8	NOUN
ctmj-188	129	7	cells	cell	NOUN
ctmj-188	129	8	(	(	PUNCT
ctmj-188	129	9	×200	×200	PROPN
ctmj-188	129	10	,	,	PUNCT
ctmj-188	129	11	scale	scale	NOUN
ctmj-188	129	12	bar	bar	NOUN
ctmj-188	129	13	=	=	NOUN
ctmj-188	129	14	100	100	NUM
ctmj-188	129	15	m	m	NOUN
ctmj-188	129	16	)	)	PUNCT
ctmj-188	129	17	.	.	PUNCT
ctmj-188	130	1	(	(	PUNCT
ctmj-188	130	2	c	c	X
ctmj-188	130	3	)	)	PUNCT
ctmj-188	130	4	tumor	tumor	NOUN
ctmj-188	130	5	volume	volume	NOUN
ctmj-188	130	6	in	in	ADP
ctmj-188	130	7	xenograft	xenograft	NOUN
ctmj-188	130	8	mice	mouse	NOUN
ctmj-188	130	9	.	.	PUNCT
ctmj-188	131	1	(	(	PUNCT
ctmj-188	131	2	d	d	X
ctmj-188	131	3	)	)	PUNCT
ctmj-188	131	4	representative	representative	ADJ
ctmj-188	131	5	photographs	photograph	NOUN
ctmj-188	131	6	of	of	ADP
ctmj-188	131	7	tumors	tumor	NOUN
ctmj-188	131	8	in	in	ADP
ctmj-188	131	9	xenograft	xenograft	NOUN
ctmj-188	131	10	mice	mouse	NOUN
ctmj-188	131	11	.	.	PUNCT
ctmj-188	132	1	(	(	PUNCT
ctmj-188	132	2	e	e	NOUN
ctmj-188	132	3	)	)	PUNCT
ctmj-188	132	4	tumor	tumor	NOUN
ctmj-188	132	5	weight	weight	NOUN
ctmj-188	132	6	.	.	PUNCT
ctmj-188	133	1	*	*	PUNCT
ctmj-188	133	2	p	p	X
ctmj-188	133	3	<	<	X
ctmj-188	133	4	0.05	0.05	NUM
ctmj-188	133	5	compared	compare	VERB
ctmj-188	133	6	with	with	ADP
ctmj-188	133	7	the	the	DET
ctmj-188	133	8	control	control	NOUN
ctmj-188	133	9	group	group	NOUN
ctmj-188	133	10	;	;	PUNCT
ctmj-188	133	11	^	^	PUNCT
ctmj-188	133	12	p	p	X
ctmj-188	133	13	<	<	X
ctmj-188	133	14	0.05	0.05	NUM
ctmj-188	133	15	compared	compare	VERB
ctmj-188	133	16	with	with	ADP
ctmj-188	133	17	the	the	DET
ctmj-188	133	18	qfg	qfg	NOUN
ctmj-188	133	19	group	group	NOUN
ctmj-188	133	20	;	;	PUNCT
ctmj-188	133	21	#	#	SYM
ctmj-188	133	22	p	p	X
ctmj-188	133	23	<	<	X
ctmj-188	133	24	0.05	0.05	NUM
ctmj-188	133	25	compared	compare	VERB
ctmj-188	133	26	with	with	ADP
ctmj-188	133	27	the	the	DET
ctmj-188	133	28	5‑fu	5‑fu	PROPN
ctmj-188	133	29	group	group	NOUN
ctmj-188	133	30	.	.	PUNCT
ctmj-188	134	1	qfg	qfg	PROPN
ctmj-188	134	2	:	:	PUNCT
ctmj-188	134	3	qingjiefuzheng	qingjiefuzheng	PROPN
ctmj-188	134	4	granule	granule	PROPN
ctmj-188	134	5	,	,	PUNCT
ctmj-188	134	6	5‑fu	5‑fu	NUM
ctmj-188	134	7	:	:	PUNCT
ctmj-188	134	8	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	134	9	d1	d1	ADJ
ctmj-188	134	10	protein	protein	NOUN
ctmj-188	134	11	expression	expression	NOUN
ctmj-188	134	12	while	while	SCONJ
ctmj-188	134	13	increased	increase	VERB
ctmj-188	134	14	p53	p53	NOUN
ctmj-188	134	15	and	and	CCONJ
ctmj-188	134	16	p21	p21	NOUN
ctmj-188	134	17	levels	level	NOUN
ctmj-188	134	18	.	.	PUNCT
ctmj-188	135	1	taken	take	VERB
ctmj-188	135	2	together	together	ADV
ctmj-188	135	3	,	,	PUNCT
ctmj-188	135	4	these	these	DET
ctmj-188	135	5	results	result	NOUN
ctmj-188	135	6	suggest	suggest	VERB
ctmj-188	135	7	that	that	SCONJ
ctmj-188	135	8	qfg	qfg	NOUN
ctmj-188	135	9	combined	combine	VERB
ctmj-188	135	10	with	with	ADP
ctmj-188	135	11	5‑fu	5‑fu	PROPN
ctmj-188	135	12	synergistically	synergistically	ADV
ctmj-188	135	13	inhibits	inhibit	VERB
ctmj-188	135	14	the	the	DET
ctmj-188	135	15	proliferation	proliferation	NOUN
ctmj-188	135	16	of	of	ADP
ctmj-188	135	17	hct‑8	hct‑8	NOUN
ctmj-188	135	18	cells	cell	NOUN
ctmj-188	135	19	both	both	CCONJ
ctmj-188	135	20	in	in	ADP
ctmj-188	135	21	vitro	vitro	X
ctmj-188	135	22	and	and	CCONJ
ctmj-188	135	23	in	in	ADP
ctmj-188	135	24	vivo	vivo	NOUN
ctmj-188	135	25	.	.	PUNCT
ctmj-188	136	1	qingjie	qingjie	PROPN
ctmj-188	136	2	fuzheng	fuzheng	PROPN
ctmj-188	136	3	granule	granule	PROPN
ctmj-188	136	4	and	and	CCONJ
ctmj-188	136	5	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	136	6	synergisticly	synergisticly	ADV
ctmj-188	136	7	promoted	promote	VERB
ctmj-188	136	8	apoptosis	apoptosis	NOUN
ctmj-188	136	9	of	of	ADP
ctmj-188	136	10	hct‑8	hct‑8	NOUN
ctmj-188	136	11	cells	cell	NOUN
ctmj-188	136	12	as	as	SCONJ
ctmj-188	136	13	shown	show	VERB
ctmj-188	136	14	in	in	ADP
ctmj-188	136	15	figure	figure	NOUN
ctmj-188	136	16	4a‑d	4a‑d	NUM
ctmj-188	136	17	,	,	PUNCT
ctmj-188	136	18	qfg	qfg	NOUN
ctmj-188	136	19	combined	combine	VERB
ctmj-188	136	20	with	with	ADP
ctmj-188	136	21	5‑fu	5‑fu	PROPN
ctmj-188	136	22	promoted	promote	VERB
ctmj-188	136	23	apoptosis	apoptosis	NOUN
ctmj-188	136	24	in	in	ADP
ctmj-188	136	25	hct-8	hct-8	PUNCT
ctmj-188	136	26	cells	cell	NOUN
ctmj-188	136	27	compared	compare	VERB
ctmj-188	136	28	to	to	ADP
ctmj-188	136	29	the	the	DET
ctmj-188	136	30	single	single	ADJ
ctmj-188	136	31	drug	drug	NOUN
ctmj-188	136	32	groups	group	NOUN
ctmj-188	136	33	,	,	PUNCT
ctmj-188	136	34	as	as	SCONJ
ctmj-188	136	35	demonstrated	demonstrate	VERB
ctmj-188	136	36	by	by	ADP
ctmj-188	136	37	annexin	annexin	NOUN
ctmj-188	136	38	v	v	ADP
ctmj-188	136	39	/	/	SYM
ctmj-188	136	40	pi	pi	NOUN
ctmj-188	136	41	staining	stain	VERB
ctmj-188	136	42	(	(	PUNCT
ctmj-188	136	43	p	p	X
ctmj-188	136	44	<	<	X
ctmj-188	136	45	0.05	0.05	NUM
ctmj-188	136	46	)	)	PUNCT
ctmj-188	136	47	and	and	CCONJ
ctmj-188	136	48	dapi	dapi	ADJ
ctmj-188	136	49	staining	stain	VERB
ctmj-188	136	50	assay	assay	NOUN
ctmj-188	136	51	(	(	PUNCT
ctmj-188	136	52	p	p	X
ctmj-188	136	53	<	<	X
ctmj-188	136	54	0.05	0.05	NUM
ctmj-188	136	55	)	)	PUNCT
ctmj-188	136	56	.	.	PUNCT
ctmj-188	137	1	furthermore	furthermore	ADV
ctmj-188	137	2	,	,	PUNCT
ctmj-188	137	3	in	in	ADP
ctmj-188	137	4	xenograft	xenograft	NOUN
ctmj-188	137	5	mice	mouse	NOUN
ctmj-188	137	6	,	,	PUNCT
ctmj-188	137	7	treatment	treatment	NOUN
ctmj-188	137	8	with	with	ADP
ctmj-188	137	9	qfg	qfg	NOUN
ctmj-188	137	10	and	and	CCONJ
ctmj-188	137	11	5‑fu	5‑fu	PROPN
ctmj-188	137	12	increased	increase	VERB
ctmj-188	137	13	the	the	DET
ctmj-188	137	14	expression	expression	NOUN
ctmj-188	137	15	of	of	ADP
ctmj-188	137	16	tunel	tunel	ADJ
ctmj-188	137	17	positive	positive	ADJ
ctmj-188	137	18	cells	cell	NOUN
ctmj-188	137	19	(	(	PUNCT
ctmj-188	137	20	p	p	X
ctmj-188	137	21	<	<	X
ctmj-188	137	22	0.05	0.05	NUM
ctmj-188	137	23	)	)	PUNCT
ctmj-188	137	24	as	as	SCONJ
ctmj-188	137	25	shown	show	VERB
ctmj-188	137	26	by	by	ADP
ctmj-188	137	27	immunofluorescence	immunofluorescence	NOUN
ctmj-188	137	28	staining	stain	VERB
ctmj-188	138	1	[	[	X
ctmj-188	138	2	figure	figure	NOUN
ctmj-188	138	3	5a	5a	NUM
ctmj-188	138	4	and	and	CCONJ
ctmj-188	138	5	b	b	NOUN
ctmj-188	138	6	]	]	X
ctmj-188	138	7	.	.	PUNCT
ctmj-188	139	1	in	in	ADP
ctmj-188	139	2	addition	addition	NOUN
ctmj-188	139	3	,	,	PUNCT
ctmj-188	139	4	apoptosis	apoptosis	NOUN
ctmj-188	139	5	-	-	PUNCT
ctmj-188	139	6	related	relate	VERB
ctmj-188	139	7	proteins	protein	NOUN
ctmj-188	139	8	expression	expression	NOUN
ctmj-188	139	9	was	be	AUX
ctmj-188	139	10	determined	determine	VERB
ctmj-188	139	11	.	.	PUNCT
ctmj-188	140	1	as	as	SCONJ
ctmj-188	140	2	shown	show	VERB
ctmj-188	140	3	in	in	ADP
ctmj-188	140	4	figures	figure	NOUN
ctmj-188	140	5	4e	4e	NOUN
ctmj-188	140	6	and	and	CCONJ
ctmj-188	140	7	f	f	PROPN
ctmj-188	140	8	and	and	CCONJ
ctmj-188	140	9	5c	5c	NUM
ctmj-188	140	10	and	and	CCONJ
ctmj-188	140	11	d	d	NOUN
ctmj-188	140	12	,	,	PUNCT
ctmj-188	140	13	qfg	qfg	NOUN
ctmj-188	140	14	combined	combine	VERB
ctmj-188	140	15	with	with	ADP
ctmj-188	140	16	5‑fu	5‑fu	PROPN
ctmj-188	140	17	increased	increase	VERB
ctmj-188	140	18	bax	bax	PROPN
ctmj-188	140	19	and	and	CCONJ
ctmj-188	140	20	cleaved‑caspase‑3	cleaved‑caspase‑3	PROPN
ctmj-188	140	21	protein	protein	NOUN
ctmj-188	140	22	expression	expression	NOUN
ctmj-188	140	23	while	while	SCONJ
ctmj-188	140	24	decreased	decrease	VERB
ctmj-188	140	25	of	of	ADP
ctmj-188	140	26	bcl-2	bcl-2	VERB
ctmj-188	140	27	protein	protein	NOUN
ctmj-188	140	28	expression	expression	NOUN
ctmj-188	140	29	,	,	PUNCT
ctmj-188	140	30	both	both	CCONJ
ctmj-188	140	31	in	in	ADP
ctmj-188	140	32	vitro	vitro	X
ctmj-188	140	33	and	and	CCONJ
ctmj-188	140	34	in	in	ADP
ctmj-188	140	35	vivo	vivo	NOUN
ctmj-188	140	36	(	(	PUNCT
ctmj-188	140	37	p	p	X
ctmj-188	140	38	<	<	X
ctmj-188	140	39	0.05	0.05	NUM
ctmj-188	140	40	)	)	PUNCT
ctmj-188	140	41	.	.	PUNCT
ctmj-188	141	1	these	these	DET
ctmj-188	141	2	results	result	NOUN
ctmj-188	141	3	suggest	suggest	VERB
ctmj-188	141	4	that	that	SCONJ
ctmj-188	141	5	qfg	qfg	NOUN
ctmj-188	141	6	and	and	CCONJ
ctmj-188	141	7	5‑fu	5‑fu	PROPN
ctmj-188	141	8	synergistically	synergistically	ADV
ctmj-188	141	9	promotes	promote	VERB
ctmj-188	141	10	apoptosis	apoptosis	NOUN
ctmj-188	141	11	in	in	ADP
ctmj-188	141	12	vitro	vitro	X
ctmj-188	141	13	and	and	CCONJ
ctmj-188	141	14	in	in	ADP
ctmj-188	141	15	vivo	vivo	NOUN
ctmj-188	141	16	.	.	PUNCT
ctmj-188	142	1	qingjie	qingjie	PROPN
ctmj-188	142	2	fuzheng	fuzheng	PROPN
ctmj-188	142	3	granule	granule	PROPN
ctmj-188	142	4	combined	combine	VERB
ctmj-188	142	5	with	with	ADP
ctmj-188	142	6	and	and	CCONJ
ctmj-188	142	7	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	142	8	synergistically	synergistically	ADV
ctmj-188	142	9	inhibited	inhibit	VERB
ctmj-188	142	10	migration	migration	NOUN
ctmj-188	142	11	and	and	CCONJ
ctmj-188	142	12	invasion	invasion	NOUN
ctmj-188	142	13	of	of	ADP
ctmj-188	142	14	hct‑8	hct‑8	NOUN
ctmj-188	142	15	cells	cell	NOUN
ctmj-188	142	16	as	as	SCONJ
ctmj-188	142	17	shown	show	VERB
ctmj-188	142	18	in	in	ADP
ctmj-188	142	19	figure	figure	NOUN
ctmj-188	142	20	6a	6a	NOUN
ctmj-188	142	21	-	-	SYM
ctmj-188	142	22	d	d	NOUN
ctmj-188	142	23	,	,	PUNCT
ctmj-188	142	24	compared	compare	VERB
ctmj-188	142	25	to	to	ADP
ctmj-188	142	26	the	the	DET
ctmj-188	142	27	individual	individual	ADJ
ctmj-188	142	28	treatment	treatment	NOUN
ctmj-188	142	29	,	,	PUNCT
ctmj-188	142	30	qfg	qfg	NOUN
ctmj-188	142	31	and	and	CCONJ
ctmj-188	142	32	5‑fu	5‑fu	NUM
ctmj-188	142	33	inhibited	inhibit	VERB
ctmj-188	142	34	migration	migration	NOUN
ctmj-188	142	35	and	and	CCONJ
ctmj-188	142	36	invasion	invasion	NOUN
ctmj-188	142	37	of	of	ADP
ctmj-188	142	38	hct-8	hct-8	PUNCT
ctmj-188	142	39	cells	cell	NOUN
ctmj-188	142	40	(	(	PUNCT
ctmj-188	142	41	both	both	CCONJ
ctmj-188	142	42	p	p	X
ctmj-188	142	43	<	<	X
ctmj-188	142	44	0.05	0.05	NUM
ctmj-188	142	45	)	)	PUNCT
ctmj-188	142	46	.	.	PUNCT
ctmj-188	143	1	meanwhile	meanwhile	ADV
ctmj-188	143	2	,	,	PUNCT
ctmj-188	143	3	we	we	PRON
ctmj-188	143	4	detected	detect	VERB
ctmj-188	143	5	emt	emt	PROPN
ctmj-188	143	6	-	-	PUNCT
ctmj-188	143	7	related	relate	VERB
ctmj-188	143	8	proteins	protein	NOUN
ctmj-188	143	9	expression	expression	NOUN
ctmj-188	143	10	.	.	PUNCT
ctmj-188	144	1	as	as	SCONJ
ctmj-188	144	2	shown	show	VERB
ctmj-188	144	3	in	in	ADP
ctmj-188	144	4	figure	figure	NOUN
ctmj-188	144	5	6e	6e	NUM
ctmj-188	144	6	-	-	PUNCT
ctmj-188	144	7	h	h	NOUN
ctmj-188	144	8	,	,	PUNCT
ctmj-188	144	9	qfg	qfg	NOUN
ctmj-188	144	10	combined	combine	VERB
ctmj-188	144	11	with	with	ADP
ctmj-188	144	12	5‑fu	5‑fu	PROPN
ctmj-188	144	13	increased	increase	VERB
ctmj-188	144	14	e‑cadherin	e‑cadherin	NOUN
ctmj-188	144	15	protein	protein	NOUN
ctmj-188	144	16	expression	expression	NOUN
ctmj-188	144	17	and	and	CCONJ
ctmj-188	144	18	decreased	decrease	VERB
ctmj-188	144	19	n‑cadherin	n‑cadherin	PROPN
ctmj-188	144	20	and	and	CCONJ
ctmj-188	144	21	vimentin	vimentin	ADJ
ctmj-188	144	22	protein	protein	NOUN
ctmj-188	144	23	expression	expression	NOUN
ctmj-188	144	24	in	in	ADP
ctmj-188	144	25	both	both	DET
ctmj-188	144	26	hct-8	hct-8	NOUN
ctmj-188	144	27	cells	cell	NOUN
ctmj-188	144	28	and	and	CCONJ
ctmj-188	144	29	tumor	tumor	NOUN
ctmj-188	144	30	tissues	tissue	NOUN
ctmj-188	144	31	.	.	PUNCT
ctmj-188	145	1	these	these	DET
ctmj-188	145	2	results	result	NOUN
ctmj-188	145	3	further	far	ADV
ctmj-188	145	4	support	support	VERB
ctmj-188	145	5	the	the	DET
ctmj-188	145	6	synergistic	synergistic	ADJ
ctmj-188	145	7	effect	effect	NOUN
ctmj-188	145	8	of	of	ADP
ctmj-188	145	9	qfg	qfg	NOUN
ctmj-188	145	10	and	and	CCONJ
ctmj-188	145	11	5‑fu	5‑fu	NUM
ctmj-188	145	12	on	on	ADP
ctmj-188	145	13	the	the	DET
ctmj-188	145	14	metastasis	metastasis	NOUN
ctmj-188	145	15	of	of	ADP
ctmj-188	145	16	intestinal	intestinal	ADJ
ctmj-188	145	17	cancer	cancer	NOUN
ctmj-188	145	18	cells	cell	NOUN
ctmj-188	145	19	.	.	PUNCT
ctmj-188	146	1	qingjie	qingjie	PROPN
ctmj-188	146	2	fuzheng	fuzheng	PROPN
ctmj-188	146	3	granule	granule	PROPN
ctmj-188	146	4	combined	combine	VERB
ctmj-188	146	5	with	with	ADP
ctmj-188	146	6	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	146	7	inhibited	inhibit	VERB
ctmj-188	146	8	of	of	ADP
ctmj-188	146	9	dihydropyrimidine	dihydropyrimidine	ADJ
ctmj-188	146	10	dehydrogenase	dehydrogenase	NOUN
ctmj-188	146	11	and	and	CCONJ
ctmj-188	146	12	thymidylate	thymidylate	NOUN
ctmj-188	146	13	synthase	synthase	NOUN
ctmj-188	146	14	expression	expression	NOUN
ctmj-188	146	15	of	of	ADP
ctmj-188	146	16	hct‑8	hct‑8	NOUN
ctmj-188	146	17	cells	cell	NOUN
ctmj-188	146	18	to	to	PART
ctmj-188	146	19	investigate	investigate	VERB
ctmj-188	146	20	the	the	DET
ctmj-188	146	21	effect	effect	NOUN
ctmj-188	146	22	of	of	ADP
ctmj-188	146	23	5‑fu	5‑fu	PROPN
ctmj-188	146	24	in	in	ADP
ctmj-188	146	25	crc	crc	NOUN
ctmj-188	146	26	cells	cell	NOUN
ctmj-188	146	27	,	,	PUNCT
ctmj-188	146	28	we	we	PRON
ctmj-188	146	29	examined	examine	VERB
ctmj-188	146	30	the	the	DET
ctmj-188	146	31	expression	expression	NOUN
ctmj-188	146	32	of	of	ADP
ctmj-188	146	33	5‑fu	5‑fu	PROPN
ctmj-188	146	34	metabolism‑related	metabolism‑relate	VERB
ctmj-188	146	35	proteins	protein	NOUN
ctmj-188	146	36	.	.	PUNCT
ctmj-188	147	1	as	as	SCONJ
ctmj-188	147	2	shown	show	VERB
ctmj-188	147	3	in	in	ADP
ctmj-188	147	4	figure	figure	NOUN
ctmj-188	147	5	7	7	NUM
ctmj-188	147	6	,	,	PUNCT
ctmj-188	147	7	we	we	PRON
ctmj-188	147	8	found	find	VERB
ctmj-188	147	9	that	that	SCONJ
ctmj-188	147	10	qfg	qfg	NOUN
ctmj-188	147	11	and	and	CCONJ
ctmj-188	147	12	5‑fu	5‑fu	NUM
ctmj-188	147	13	inhibited	inhibit	VERB
ctmj-188	147	14	dihydropyrimidine	dihydropyrimidine	ADJ
ctmj-188	147	15	dehydrogenase	dehydrogenase	NOUN
ctmj-188	147	16	(	(	PUNCT
ctmj-188	147	17	dpd	dpd	PROPN
ctmj-188	147	18	)	)	PUNCT
ctmj-188	147	19	and	and	CCONJ
ctmj-188	147	20	thymidylate	thymidylate	NOUN
ctmj-188	147	21	synthase	synthase	NOUN
ctmj-188	147	22	(	(	PUNCT
ctmj-188	147	23	ts	ts	NOUN
ctmj-188	147	24	)	)	PUNCT
ctmj-188	147	25	protein	protein	NOUN
ctmj-188	147	26	expression	expression	NOUN
ctmj-188	147	27	of	of	ADP
ctmj-188	147	28	hct-8	hct-8	PUNCT
ctmj-188	147	29	in	in	ADP
ctmj-188	147	30	vitro	vitro	X
ctmj-188	147	31	and	and	CCONJ
ctmj-188	147	32	in	in	ADP
ctmj-188	147	33	vivo	vivo	NOUN
ctmj-188	147	34	(	(	PUNCT
ctmj-188	147	35	both	both	CCONJ
ctmj-188	147	36	p	p	X
ctmj-188	147	37	<	<	X
ctmj-188	147	38	0.05	0.05	NUM
ctmj-188	147	39	)	)	PUNCT
ctmj-188	148	1	[	[	X
ctmj-188	148	2	figure	figure	NOUN
ctmj-188	148	3	7	7	NUM
ctmj-188	148	4	]	]	PUNCT
ctmj-188	148	5	.	.	PUNCT
ctmj-188	149	1	qingjie	qingjie	PROPN
ctmj-188	149	2	fuzheng	fuzheng	PROPN
ctmj-188	149	3	granule	granule	PROPN
ctmj-188	149	4	combined	combine	VERB
ctmj-188	149	5	with	with	ADP
ctmj-188	149	6	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	149	7	synergistically	synergistically	ADV
ctmj-188	149	8	inhibited	inhibit	VERB
ctmj-188	149	9	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	149	10	3‑kinase/	3‑kinase/	NUM
ctmj-188	150	1	protein	protein	NOUN
ctmj-188	150	2	kinase	kinase	PROPN
ctmj-188	150	3	b	b	PROPN
ctmj-188	150	4	signaling	signal	VERB
ctmj-188	150	5	pathway	pathway	NOUN
ctmj-188	150	6	of	of	ADP
ctmj-188	150	7	hct‑8	hct‑8	NOUN
ctmj-188	150	8	cells	cell	NOUN
ctmj-188	150	9	to	to	PART
ctmj-188	150	10	explore	explore	VERB
ctmj-188	150	11	the	the	DET
ctmj-188	150	12	effect	effect	NOUN
ctmj-188	150	13	of	of	ADP
ctmj-188	150	14	qfg	qfg	NOUN
ctmj-188	150	15	combined	combine	VERB
ctmj-188	150	16	with	with	ADP
ctmj-188	150	17	5‑fu	5‑fu	PROPN
ctmj-188	150	18	on	on	ADP
ctmj-188	150	19	the	the	DET
ctmj-188	150	20	pi3k	pi3k	PROPN
ctmj-188	150	21	/	/	SYM
ctmj-188	150	22	akt	akt	PROPN
ctmj-188	150	23	pathway	pathway	NOUN
ctmj-188	150	24	,	,	PUNCT
ctmj-188	150	25	we	we	PRON
ctmj-188	150	26	examined	examine	VERB
ctmj-188	150	27	it	it	PRON
ctmj-188	150	28	by	by	ADP
ctmj-188	150	29	western	western	ADJ
ctmj-188	150	30	blot	blot	NOUN
ctmj-188	150	31	analysis	analysis	NOUN
ctmj-188	150	32	and	and	CCONJ
ctmj-188	150	33	found	find	VERB
ctmj-188	150	34	that	that	SCONJ
ctmj-188	150	35	qfg	qfg	NOUN
ctmj-188	150	36	and	and	CCONJ
ctmj-188	150	37	5‑fu	5‑fu	PROPN
ctmj-188	150	38	decreased	decrease	VERB
ctmj-188	150	39	p‑pi3k	p‑pi3k	NOUN
ctmj-188	150	40	and	and	CCONJ
ctmj-188	150	41	p‑akt	p‑akt	NOUN
ctmj-188	150	42	protein	protein	NOUN
ctmj-188	150	43	expression	expression	NOUN
ctmj-188	150	44	both	both	CCONJ
ctmj-188	150	45	in	in	ADP
ctmj-188	150	46	hct‑8	hct‑8	NOUN
ctmj-188	150	47	cells	cell	NOUN
ctmj-188	150	48	and	and	CCONJ
ctmj-188	150	49	tumor	tumor	NOUN
ctmj-188	150	50	tissues	tissue	NOUN
ctmj-188	150	51	[	[	X
ctmj-188	150	52	figure	figure	NOUN
ctmj-188	150	53	8	8	NUM
ctmj-188	150	54	]	]	PUNCT
ctmj-188	150	55	.	.	PUNCT
ctmj-188	151	1	these	these	DET
ctmj-188	151	2	results	result	NOUN
ctmj-188	151	3	suggest	suggest	VERB
ctmj-188	151	4	that	that	SCONJ
ctmj-188	151	5	qfg	qfg	NOUN
ctmj-188	151	6	combined	combine	VERB
ctmj-188	151	7	with	with	ADP
ctmj-188	151	8	5‑fu	5‑fu	PROPN
ctmj-188	151	9	synergistically	synergistically	ADV
ctmj-188	151	10	inhibited	inhibit	VERB
ctmj-188	151	11	intestinal	intestinal	ADJ
ctmj-188	151	12	cancer	cancer	NOUN
ctmj-188	151	13	growth	growth	NOUN
ctmj-188	151	14	by	by	ADP
ctmj-188	151	15	suppressing	suppress	VERB
ctmj-188	151	16	the	the	DET
ctmj-188	151	17	pi3k	pi3k	PROPN
ctmj-188	151	18	/	/	SYM
ctmj-188	151	19	akt	akt	PROPN
ctmj-188	151	20	signaling	signal	VERB
ctmj-188	151	21	pathway	pathway	NOUN
ctmj-188	151	22	.	.	PUNCT
ctmj-188	152	1	a	a	DET
ctmj-188	152	2	c	c	NOUN
ctmj-188	152	3	d	d	X
ctmj-188	152	4	b	b	PROPN
ctmj-188	152	5	e	e	SYM
ctmj-188	152	6	49	49	NUM
ctmj-188	152	7	ctmj	ctmj	NOUN
ctmj-188	152	8	|	|	ADV
ctmj-188	152	9	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	152	10	chinese	chinese	ADJ
ctmj-188	152	11	traditional	traditional	ADJ
ctmj-188	152	12	medicine	medicine	NOUN
ctmj-188	152	13	journal	journal	NOUN
ctmj-188	152	14	|	|	ADV
ctmj-188	152	15	2025	2025	NUM
ctmj-188	152	16	|	|	ADV
ctmj-188	152	17	vol	vol	NOUN
ctmj-188	152	18	8	8	NUM
ctmj-188	152	19	|issue	|issue	NOUN
ctmj-188	152	20	1	1	NUM
ctmj-188	152	21	49	49	NUM
ctmj-188	152	22	figure	figure	NOUN
ctmj-188	152	23	3	3	NUM
ctmj-188	152	24	:	:	PUNCT
ctmj-188	152	25	qingjie	qingjie	NOUN
ctmj-188	152	26	fuzheng	fuzheng	PROPN
ctmj-188	152	27	granule	granule	PROPN
ctmj-188	152	28	(	(	PUNCT
ctmj-188	152	29	qfg	qfg	ADJ
ctmj-188	152	30	)	)	PUNCT
ctmj-188	152	31	and	and	CCONJ
ctmj-188	152	32	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	152	33	(	(	PUNCT
ctmj-188	152	34	5‑fu	5‑fu	PROPN
ctmj-188	152	35	)	)	PUNCT
ctmj-188	152	36	synergistically	synergistically	ADV
ctmj-188	152	37	inhibits	inhibit	VERB
ctmj-188	152	38	the	the	DET
ctmj-188	152	39	proliferation	proliferation	NOUN
ctmj-188	152	40	of	of	ADP
ctmj-188	152	41	hct‑8	hct‑8	NOUN
ctmj-188	152	42	cells	cell	NOUN
ctmj-188	152	43	in	in	ADP
ctmj-188	152	44	vitro	vitro	X
ctmj-188	152	45	and	and	CCONJ
ctmj-188	152	46	in	in	ADP
ctmj-188	152	47	vivo	vivo	NOUN
ctmj-188	152	48	.	.	PUNCT
ctmj-188	153	1	(	(	PUNCT
ctmj-188	153	2	a	a	PRON
ctmj-188	153	3	and	and	CCONJ
ctmj-188	153	4	b	b	NOUN
ctmj-188	153	5	)	)	PUNCT
ctmj-188	153	6	colony	colony	NOUN
ctmj-188	153	7	formation	formation	NOUN
ctmj-188	153	8	assay	assay	VERB
ctmj-188	153	9	.	.	PUNCT
ctmj-188	154	1	(	(	PUNCT
ctmj-188	154	2	c	c	NOUN
ctmj-188	154	3	and	and	CCONJ
ctmj-188	154	4	d	d	NOUN
ctmj-188	154	5	)	)	PUNCT
ctmj-188	154	6	proliferation‑related	proliferation‑relate	VERB
ctmj-188	154	7	proteins	protein	NOUN
ctmj-188	154	8	expression	expression	NOUN
ctmj-188	154	9	in	in	ADP
ctmj-188	154	10	hct‑8	hct‑8	NOUN
ctmj-188	154	11	cells	cell	NOUN
ctmj-188	154	12	.	.	PUNCT
ctmj-188	155	1	(	(	PUNCT
ctmj-188	155	2	e	e	NOUN
ctmj-188	155	3	and	and	CCONJ
ctmj-188	155	4	f	f	X
ctmj-188	155	5	)	)	PUNCT
ctmj-188	155	6	ki67	ki67	PROPN
ctmj-188	155	7	expression	expression	NOUN
ctmj-188	155	8	in	in	ADP
ctmj-188	155	9	xenograft	xenograft	NOUN
ctmj-188	155	10	mice	mouse	NOUN
ctmj-188	155	11	(	(	PUNCT
ctmj-188	155	12	×400	×400	NOUN
ctmj-188	155	13	,	,	PUNCT
ctmj-188	155	14	scale	scale	NOUN
ctmj-188	155	15	bar	bar	NOUN
ctmj-188	155	16	=	=	PUNCT
ctmj-188	155	17	50	50	NUM
ctmj-188	155	18	m	m	NOUN
ctmj-188	155	19	)	)	PUNCT
ctmj-188	155	20	.	.	PUNCT
ctmj-188	156	1	(	(	PUNCT
ctmj-188	156	2	g	g	NOUN
ctmj-188	156	3	and	and	CCONJ
ctmj-188	156	4	h	h	NOUN
ctmj-188	156	5	)	)	PUNCT
ctmj-188	156	6	expression	expression	NOUN
ctmj-188	156	7	of	of	ADP
ctmj-188	156	8	proliferation‑related	proliferation‑relate	VERB
ctmj-188	156	9	proteins	protein	NOUN
ctmj-188	156	10	in	in	ADP
ctmj-188	156	11	xenograft	xenograft	NOUN
ctmj-188	156	12	mice	mouse	NOUN
ctmj-188	156	13	.	.	PUNCT
ctmj-188	157	1	the	the	DET
ctmj-188	157	2	arrow	arrow	NOUN
ctmj-188	157	3	refers	refer	VERB
ctmj-188	157	4	to	to	ADP
ctmj-188	157	5	ki‑67	ki‑67	PROPN
ctmj-188	157	6	positive	positive	ADJ
ctmj-188	157	7	cell	cell	NOUN
ctmj-188	157	8	.	.	PUNCT
ctmj-188	158	1	*	*	PUNCT
ctmj-188	158	2	p	p	X
ctmj-188	158	3	<	<	X
ctmj-188	158	4	0.05	0.05	NUM
ctmj-188	158	5	compared	compare	VERB
ctmj-188	158	6	with	with	ADP
ctmj-188	158	7	the	the	DET
ctmj-188	158	8	control	control	NOUN
ctmj-188	158	9	group	group	NOUN
ctmj-188	158	10	;	;	PUNCT
ctmj-188	158	11	^	^	PUNCT
ctmj-188	158	12	p	p	X
ctmj-188	158	13	<	<	X
ctmj-188	158	14	0.05	0.05	NUM
ctmj-188	158	15	compared	compare	VERB
ctmj-188	158	16	with	with	ADP
ctmj-188	158	17	the	the	DET
ctmj-188	158	18	qfg	qfg	NOUN
ctmj-188	158	19	group	group	NOUN
ctmj-188	158	20	;	;	PUNCT
ctmj-188	158	21	#	#	SYM
ctmj-188	158	22	p	p	X
ctmj-188	158	23	<	<	X
ctmj-188	158	24	0.05	0.05	NUM
ctmj-188	158	25	compared	compare	VERB
ctmj-188	158	26	with	with	ADP
ctmj-188	158	27	the	the	DET
ctmj-188	158	28	5‑fu	5‑fu	PROPN
ctmj-188	158	29	group	group	NOUN
ctmj-188	158	30	.	.	PUNCT
ctmj-188	159	1	qfg	qfg	PROPN
ctmj-188	159	2	:	:	PUNCT
ctmj-188	159	3	qingjie	qingjie	PROPN
ctmj-188	159	4	fuzheng	fuzheng	PROPN
ctmj-188	159	5	granule	granule	PROPN
ctmj-188	159	6	,	,	PUNCT
ctmj-188	159	7	5‑fu	5‑fu	NUM
ctmj-188	159	8	:	:	PUNCT
ctmj-188	159	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	159	10	qingjie	qingjie	NOUN
ctmj-188	159	11	fuzheng	fuzheng	PROPN
ctmj-188	159	12	granule	granule	PROPN
ctmj-188	159	13	combined	combine	VERB
ctmj-188	159	14	with	with	ADP
ctmj-188	159	15	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	159	16	regulated	regulated	ADJ
ctmj-188	159	17	proliferation	proliferation	NOUN
ctmj-188	159	18	,	,	PUNCT
ctmj-188	159	19	apoptosis	apoptosis	NOUN
ctmj-188	159	20	,	,	PUNCT
ctmj-188	159	21	migration	migration	NOUN
ctmj-188	159	22	and	and	CCONJ
ctmj-188	159	23	invasion	invasion	NOUN
ctmj-188	159	24	of	of	ADP
ctmj-188	159	25	hct‑8	hct‑8	NOUN
ctmj-188	159	26	cells	cell	NOUN
ctmj-188	159	27	through	through	ADP
ctmj-188	159	28	blocking	block	VERB
ctmj-188	159	29	phosphatidylinositol	phosphatidylinositol	NOUN
ctmj-188	159	30	3‑kinase	3‑kinase	NOUN
ctmj-188	159	31	/	/	SYM
ctmj-188	159	32	protein	protein	NOUN
ctmj-188	159	33	kinase	kinase	PROPN
ctmj-188	159	34	b	b	PROPN
ctmj-188	159	35	pathway	pathway	PROPN
ctmj-188	159	36	fbs	fbs	PROPN
ctmj-188	159	37	,	,	PUNCT
ctmj-188	159	38	as	as	ADP
ctmj-188	159	39	an	an	DET
ctmj-188	159	40	important	important	ADJ
ctmj-188	159	41	exogenous	exogenous	ADJ
ctmj-188	159	42	environmental	environmental	ADJ
ctmj-188	159	43	factor	factor	NOUN
ctmj-188	159	44	containing	contain	VERB
ctmj-188	159	45	lots	lot	NOUN
ctmj-188	159	46	of	of	ADP
ctmj-188	159	47	growth	growth	NOUN
ctmj-188	159	48	factors	factor	NOUN
ctmj-188	159	49	,	,	PUNCT
ctmj-188	159	50	plays	play	VERB
ctmj-188	159	51	an	an	DET
ctmj-188	159	52	important	important	ADJ
ctmj-188	159	53	role	role	NOUN
ctmj-188	159	54	in	in	ADP
ctmj-188	159	55	cell	cell	NOUN
ctmj-188	159	56	signaling	signal	VERB
ctmj-188	159	57	by	by	ADP
ctmj-188	159	58	binding	bind	VERB
ctmj-188	159	59	to	to	ADP
ctmj-188	159	60	growth	growth	NOUN
ctmj-188	159	61	factor	factor	NOUN
ctmj-188	159	62	receptors	receptor	NOUN
ctmj-188	159	63	on	on	ADP
ctmj-188	159	64	the	the	DET
ctmj-188	159	65	cell	cell	NOUN
ctmj-188	159	66	membrane	membrane	NOUN
ctmj-188	159	67	and	and	CCONJ
ctmj-188	159	68	inducing	induce	VERB
ctmj-188	159	69	changes	change	NOUN
ctmj-188	159	70	in	in	ADP
ctmj-188	159	71	the	the	DET
ctmj-188	159	72	signaling	signal	VERB
ctmj-188	159	73	pathway‑related	pathway‑relate	VERB
ctmj-188	159	74	proteins	protein	NOUN
ctmj-188	159	75	.	.	PUNCT
ctmj-188	160	1	to	to	PART
ctmj-188	160	2	explore	explore	VERB
ctmj-188	160	3	the	the	DET
ctmj-188	160	4	effect	effect	NOUN
ctmj-188	160	5	of	of	ADP
ctmj-188	160	6	fbs	fbs	PROPN
ctmj-188	160	7	on	on	ADP
ctmj-188	160	8	the	the	DET
ctmj-188	160	9	pi3k	pi3k	PROPN
ctmj-188	160	10	/	/	SYM
ctmj-188	160	11	akt	akt	PROPN
ctmj-188	160	12	pathway	pathway	NOUN
ctmj-188	160	13	,	,	PUNCT
ctmj-188	160	14	we	we	PRON
ctmj-188	160	15	subjected	subject	VERB
ctmj-188	160	16	hct‑8	hct‑8	NOUN
ctmj-188	160	17	cells	cell	NOUN
ctmj-188	160	18	to	to	ADP
ctmj-188	160	19	10	10	NUM
ctmj-188	160	20	%	%	NOUN
ctmj-188	160	21	fbs	fbs	NOUN
ctmj-188	160	22	intervention	intervention	NOUN
ctmj-188	160	23	under	under	ADP
ctmj-188	160	24	starvation	starvation	NOUN
ctmj-188	160	25	condition	condition	NOUN
ctmj-188	160	26	for	for	ADP
ctmj-188	160	27	different	different	ADJ
ctmj-188	160	28	durations	duration	NOUN
ctmj-188	160	29	.	.	PUNCT
ctmj-188	161	1	the	the	DET
ctmj-188	161	2	results	result	NOUN
ctmj-188	161	3	are	be	AUX
ctmj-188	161	4	shown	show	VERB
ctmj-188	161	5	in	in	ADP
ctmj-188	161	6	figure	figure	NOUN
ctmj-188	161	7	9a	9a	NOUN
ctmj-188	161	8	and	and	CCONJ
ctmj-188	161	9	b	b	NOUN
ctmj-188	161	10	demonstrate	demonstrate	VERB
ctmj-188	161	11	that	that	SCONJ
ctmj-188	161	12	10	10	NUM
ctmj-188	161	13	%	%	NOUN
ctmj-188	161	14	fbs	fb	VERB
ctmj-188	161	15	intervention	intervention	NOUN
ctmj-188	161	16	for	for	ADP
ctmj-188	161	17	30	30	NUM
ctmj-188	161	18	min	min	NOUN
ctmj-188	161	19	significantly	significantly	ADV
ctmj-188	161	20	upregulated	upregulate	VERB
ctmj-188	161	21	p‑akt	p‑akt	NOUN
ctmj-188	161	22	protein	protein	NOUN
ctmj-188	161	23	expression	expression	NOUN
ctmj-188	161	24	(	(	PUNCT
ctmj-188	161	25	p	p	X
ctmj-188	161	26	<	<	X
ctmj-188	161	27	0.05	0.05	NUM
ctmj-188	161	28	)	)	PUNCT
ctmj-188	161	29	,	,	PUNCT
ctmj-188	161	30	indicating	indicate	VERB
ctmj-188	161	31	the	the	DET
ctmj-188	161	32	activation	activation	NOUN
ctmj-188	161	33	of	of	ADP
ctmj-188	161	34	the	the	DET
ctmj-188	161	35	pi3k	pi3k	PROPN
ctmj-188	161	36	/	/	SYM
ctmj-188	161	37	akt	akt	PROPN
ctmj-188	161	38	signaling	signal	VERB
ctmj-188	161	39	pathway	pathway	NOUN
ctmj-188	161	40	in	in	ADP
ctmj-188	161	41	hct‑8	hct‑8	NOUN
ctmj-188	161	42	cells	cell	NOUN
ctmj-188	161	43	by	by	ADP
ctmj-188	161	44	10	10	NUM
ctmj-188	161	45	%	%	NOUN
ctmj-188	161	46	fbs	fbs	PROPN
ctmj-188	161	47	intervention	intervention	NOUN
ctmj-188	161	48	.	.	PUNCT
ctmj-188	162	1	a	a	DET
ctmj-188	162	2	b	b	X
ctmj-188	162	3	c	c	NOUN
ctmj-188	162	4	d	d	X
ctmj-188	162	5	e	e	X
ctmj-188	162	6	f	f	PROPN
ctmj-188	162	7	g	g	PROPN
ctmj-188	162	8	h	h	PROPN
ctmj-188	162	9	50	50	NUM
ctmj-188	162	10	ctmj	ctmj	NOUN
ctmj-188	162	11	|	|	ADV
ctmj-188	162	12	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	162	13	chinese	chinese	ADJ
ctmj-188	162	14	traditional	traditional	ADJ
ctmj-188	162	15	medicine	medicine	NOUN
ctmj-188	162	16	journal	journal	NOUN
ctmj-188	162	17	|	|	ADV
ctmj-188	162	18	2025	2025	NUM
ctmj-188	162	19	|	|	ADV
ctmj-188	162	20	vol	vol	NOUN
ctmj-188	162	21	8	8	NUM
ctmj-188	162	22	|issue	|issue	NOUN
ctmj-188	162	23	1	1	NUM
ctmj-188	162	24	50	50	NUM
ctmj-188	162	25	figure	figure	NOUN
ctmj-188	162	26	4	4	NUM
ctmj-188	162	27	:	:	PUNCT
ctmj-188	162	28	qingjie	qingjie	PROPN
ctmj-188	162	29	fuzheng	fuzheng	PROPN
ctmj-188	162	30	granule	granule	PROPN
ctmj-188	162	31	(	(	PUNCT
ctmj-188	162	32	qfg	qfg	NOUN
ctmj-188	162	33	)	)	PUNCT
ctmj-188	162	34	combined	combine	VERB
ctmj-188	162	35	with	with	ADP
ctmj-188	162	36	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	162	37	(	(	PUNCT
ctmj-188	162	38	5‑fu	5‑fu	PROPN
ctmj-188	162	39	)	)	PUNCT
ctmj-188	162	40	synergisticly	synergisticly	ADV
ctmj-188	162	41	promoted	promote	VERB
ctmj-188	162	42	apoptosis	apoptosis	NOUN
ctmj-188	162	43	in	in	ADP
ctmj-188	162	44	hct‑8	hct‑8	NOUN
ctmj-188	162	45	cells	cell	NOUN
ctmj-188	162	46	.	.	PUNCT
ctmj-188	163	1	(	(	PUNCT
ctmj-188	163	2	a	a	PRON
ctmj-188	163	3	and	and	CCONJ
ctmj-188	163	4	b	b	NOUN
ctmj-188	163	5	)	)	PUNCT
ctmj-188	163	6	annexin	annexin	NOUN
ctmj-188	163	7	v	v	ADP
ctmj-188	163	8	/	/	SYM
ctmj-188	163	9	pi	pi	NOUN
ctmj-188	163	10	staining	stain	VERB
ctmj-188	163	11	analyzed	analyze	VERB
ctmj-188	163	12	by	by	ADP
ctmj-188	163	13	flow	flow	NOUN
ctmj-188	163	14	cytometry	cytometry	NOUN
ctmj-188	163	15	.	.	PUNCT
ctmj-188	164	1	(	(	PUNCT
ctmj-188	164	2	c	c	NOUN
ctmj-188	164	3	and	and	CCONJ
ctmj-188	164	4	d	d	NOUN
ctmj-188	164	5	)	)	PUNCT
ctmj-188	164	6	dapi	dapi	ADV
ctmj-188	164	7	staining	stain	VERB
ctmj-188	164	8	(	(	PUNCT
ctmj-188	164	9	×200	×200	PROPN
ctmj-188	164	10	,	,	PUNCT
ctmj-188	164	11	bar	bar	NOUN
ctmj-188	164	12	=	=	PUNCT
ctmj-188	164	13	100	100	NUM
ctmj-188	164	14	m	m	NOUN
ctmj-188	164	15	)	)	PUNCT
ctmj-188	164	16	.	.	PUNCT
ctmj-188	165	1	(	(	PUNCT
ctmj-188	165	2	e	e	NOUN
ctmj-188	165	3	and	and	CCONJ
ctmj-188	165	4	f	f	X
ctmj-188	165	5	)	)	PUNCT
ctmj-188	165	6	expression	expression	NOUN
ctmj-188	165	7	of	of	ADP
ctmj-188	165	8	apoptosis‑related	apoptosis‑relate	VERB
ctmj-188	165	9	protein	protein	NOUN
ctmj-188	165	10	in	in	ADP
ctmj-188	165	11	hct‑8	hct‑8	NOUN
ctmj-188	165	12	cells	cell	NOUN
ctmj-188	165	13	.	.	PUNCT
ctmj-188	166	1	*	*	PUNCT
ctmj-188	166	2	p	p	X
ctmj-188	166	3	<	<	X
ctmj-188	166	4	0.05	0.05	NUM
ctmj-188	166	5	compared	compare	VERB
ctmj-188	166	6	to	to	ADP
ctmj-188	166	7	the	the	DET
ctmj-188	166	8	control	control	NOUN
ctmj-188	166	9	group	group	NOUN
ctmj-188	166	10	;	;	PUNCT
ctmj-188	166	11	^	^	PUNCT
ctmj-188	166	12	p	p	X
ctmj-188	166	13	<	<	X
ctmj-188	166	14	0.05	0.05	NUM
ctmj-188	166	15	compared	compare	VERB
ctmj-188	166	16	to	to	ADP
ctmj-188	166	17	the	the	DET
ctmj-188	166	18	qfg	qfg	ADJ
ctmj-188	166	19	group	group	NOUN
ctmj-188	166	20	;	;	PUNCT
ctmj-188	166	21	#	#	SYM
ctmj-188	166	22	p	p	X
ctmj-188	166	23	<	<	X
ctmj-188	166	24	0.05	0.05	NUM
ctmj-188	166	25	compared	compare	VERB
ctmj-188	166	26	to	to	ADP
ctmj-188	166	27	the	the	DET
ctmj-188	166	28	5‑fu	5‑fu	PROPN
ctmj-188	166	29	group	group	NOUN
ctmj-188	166	30	.	.	PUNCT
ctmj-188	167	1	qfg	qfg	PROPN
ctmj-188	167	2	:	:	PUNCT
ctmj-188	167	3	qingjie	qingjie	PROPN
ctmj-188	167	4	fuzheng	fuzheng	PROPN
ctmj-188	167	5	granule	granule	PROPN
ctmj-188	167	6	,	,	PUNCT
ctmj-188	167	7	5‑fu	5‑fu	NUM
ctmj-188	167	8	:	:	PUNCT
ctmj-188	167	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	167	10	next	next	ADV
ctmj-188	167	11	,	,	PUNCT
ctmj-188	167	12	we	we	PRON
ctmj-188	167	13	investigated	investigate	VERB
ctmj-188	167	14	whether	whether	SCONJ
ctmj-188	167	15	qfg	qfg	NOUN
ctmj-188	167	16	combined	combine	VERB
ctmj-188	167	17	with	with	ADP
ctmj-188	167	18	5‑fu	5‑fu	PROPN
ctmj-188	167	19	synergistically	synergistically	ADV
ctmj-188	167	20	regulated	regulate	VERB
ctmj-188	167	21	the	the	DET
ctmj-188	167	22	proliferation	proliferation	NOUN
ctmj-188	167	23	,	,	PUNCT
ctmj-188	167	24	apoptosis	apoptosis	NOUN
ctmj-188	167	25	,	,	PUNCT
ctmj-188	167	26	migration	migration	NOUN
ctmj-188	167	27	,	,	PUNCT
ctmj-188	167	28	and	and	CCONJ
ctmj-188	167	29	invasion	invasion	NOUN
ctmj-188	167	30	of	of	ADP
ctmj-188	167	31	hct‑8	hct‑8	NOUN
ctmj-188	167	32	cells	cell	NOUN
ctmj-188	167	33	via	via	ADP
ctmj-188	167	34	pi3k	pi3k	PROPN
ctmj-188	167	35	/	/	SYM
ctmj-188	167	36	akt	akt	PROPN
ctmj-188	167	37	pathway	pathway	NOUN
ctmj-188	167	38	.	.	PUNCT
ctmj-188	168	1	moreover	moreover	ADV
ctmj-188	168	2	,	,	PUNCT
ctmj-188	168	3	qfg	qfg	NOUN
ctmj-188	168	4	combined	combine	VERB
ctmj-188	168	5	with	with	ADP
ctmj-188	168	6	5‑fu	5‑fu	PROPN
ctmj-188	168	7	blocked	block	VERB
ctmj-188	168	8	the	the	DET
ctmj-188	168	9	activstion	activstion	NOUN
ctmj-188	168	10	of	of	ADP
ctmj-188	168	11	akt	akt	PROPN
ctmj-188	168	12	induced	induce	VERB
ctmj-188	168	13	by	by	ADP
ctmj-188	168	14	fbs	fbs	PROPN
ctmj-188	169	1	[	[	X
ctmj-188	169	2	figure	figure	NOUN
ctmj-188	169	3	9c	9c	NUM
ctmj-188	169	4	and	and	CCONJ
ctmj-188	169	5	d	d	NOUN
ctmj-188	169	6	]	]	X
ctmj-188	169	7	.	.	PUNCT
ctmj-188	170	1	as	as	SCONJ
ctmj-188	170	2	shown	show	VERB
ctmj-188	170	3	in	in	ADP
ctmj-188	170	4	figure	figure	NOUN
ctmj-188	170	5	10a	10a	NOUN
ctmj-188	170	6	,	,	PUNCT
ctmj-188	170	7	qfg	qfg	NOUN
ctmj-188	170	8	and	and	CCONJ
ctmj-188	170	9	5‑fu	5‑fu	NUM
ctmj-188	170	10	significantly	significantly	ADV
ctmj-188	170	11	inhibited	inhibit	VERB
ctmj-188	170	12	cell	cell	NOUN
ctmj-188	170	13	growth	growth	NOUN
ctmj-188	170	14	in	in	ADP
ctmj-188	170	15	hct-8	hct-8	PUNCT
ctmj-188	170	16	cells	cell	NOUN
ctmj-188	170	17	.	.	PUNCT
ctmj-188	171	1	similarly	similarly	ADV
ctmj-188	171	2	,	,	PUNCT
ctmj-188	171	3	the	the	DET
ctmj-188	171	4	results	result	NOUN
ctmj-188	171	5	in	in	ADP
ctmj-188	171	6	figure	figure	NOUN
ctmj-188	171	7	10b	10b	NOUN
ctmj-188	171	8	and	and	CCONJ
ctmj-188	171	9	c	c	NOUN
ctmj-188	171	10	demonstrated	demonstrate	VERB
ctmj-188	171	11	that	that	SCONJ
ctmj-188	171	12	qfg	qfg	NOUN
ctmj-188	171	13	and	and	CCONJ
ctmj-188	171	14	5‑fu	5‑fu	PROPN
ctmj-188	171	15	reduced	reduce	VERB
ctmj-188	171	16	the	the	DET
ctmj-188	171	17	number	number	NOUN
ctmj-188	171	18	of	of	ADP
ctmj-188	171	19	colonies	colony	NOUN
ctmj-188	171	20	which	which	PRON
ctmj-188	171	21	was	be	AUX
ctmj-188	171	22	induced	induce	VERB
ctmj-188	171	23	by	by	ADP
ctmj-188	171	24	pi3k	pi3k	PROPN
ctmj-188	171	25	/	/	SYM
ctmj-188	171	26	akt	akt	PROPN
ctmj-188	171	27	pathway	pathway	NOUN
ctmj-188	171	28	activation	activation	NOUN
ctmj-188	171	29	(	(	PUNCT
ctmj-188	171	30	p	p	X
ctmj-188	171	31	<	<	X
ctmj-188	171	32	0.05	0.05	NUM
ctmj-188	171	33	)	)	PUNCT
ctmj-188	171	34	.	.	PUNCT
ctmj-188	172	1	furthermore	furthermore	ADV
ctmj-188	172	2	,	,	PUNCT
ctmj-188	172	3	qfg	qfg	NOUN
ctmj-188	172	4	and	and	CCONJ
ctmj-188	172	5	5‑fu	5‑fu	PROPN
ctmj-188	172	6	promoted	promote	VERB
ctmj-188	172	7	apoptosis	apoptosis	NOUN
ctmj-188	172	8	significantly	significantly	ADV
ctmj-188	172	9	(	(	PUNCT
ctmj-188	172	10	p	p	X
ctmj-188	172	11	<	<	X
ctmj-188	172	12	0.05	0.05	NUM
ctmj-188	172	13	)	)	PUNCT
ctmj-188	172	14	as	as	SCONJ
ctmj-188	172	15	shown	show	VERB
ctmj-188	172	16	in	in	ADP
ctmj-188	172	17	figure	figure	NOUN
ctmj-188	172	18	10d	10d	PROPN
ctmj-188	172	19	and	and	CCONJ
ctmj-188	172	20	e.	e.	PROPN
ctmj-188	172	21	moreover	moreover	ADV
ctmj-188	172	22	,	,	PUNCT
ctmj-188	172	23	qfg	qfg	ADJ
ctmj-188	172	24	and	and	CCONJ
ctmj-188	172	25	5	5	NUM
ctmj-188	172	26	fu	fu	NOUN
ctmj-188	172	27	suppressed	suppress	VERB
ctmj-188	172	28	migration	migration	NOUN
ctmj-188	172	29	and	and	CCONJ
ctmj-188	172	30	invasion	invasion	NOUN
ctmj-188	172	31	(	(	PUNCT
ctmj-188	172	32	both	both	CCONJ
ctmj-188	172	33	p	p	X
ctmj-188	172	34	<	<	X
ctmj-188	172	35	0.05	0.05	NUM
ctmj-188	172	36	)	)	PUNCT
ctmj-188	172	37	which	which	PRON
ctmj-188	172	38	were	be	AUX
ctmj-188	172	39	promoted	promote	VERB
ctmj-188	172	40	by	by	ADP
ctmj-188	172	41	pi3k	pi3k	PROPN
ctmj-188	172	42	/	/	SYM
ctmj-188	172	43	akt	akt	PROPN
ctmj-188	172	44	pathway	pathway	NOUN
ctmj-188	172	45	activation	activation	NOUN
ctmj-188	172	46	as	as	SCONJ
ctmj-188	172	47	shown	show	VERB
ctmj-188	172	48	in	in	ADP
ctmj-188	172	49	figure	figure	NOUN
ctmj-188	172	50	10f	10f	PROPN
ctmj-188	172	51	and	and	CCONJ
ctmj-188	172	52	g	g	PROPN
ctmj-188	172	53	and	and	CCONJ
ctmj-188	172	54	figure	figure	VERB
ctmj-188	172	55	10h	10h	NUM
ctmj-188	172	56	and	and	CCONJ
ctmj-188	172	57	i.	i.	NOUN
ctmj-188	172	58	in	in	ADP
ctmj-188	172	59	conclusion	conclusion	NOUN
ctmj-188	172	60	,	,	PUNCT
ctmj-188	172	61	these	these	DET
ctmj-188	172	62	results	result	NOUN
ctmj-188	172	63	suggest	suggest	VERB
ctmj-188	172	64	that	that	SCONJ
ctmj-188	172	65	qfg	qfg	NOUN
ctmj-188	172	66	and	and	CCONJ
ctmj-188	172	67	5‑fu	5‑fu	PROPN
ctmj-188	172	68	synergistically	synergistically	ADV
ctmj-188	172	69	regulated	regulate	VERB
ctmj-188	172	70	the	the	DET
ctmj-188	172	71	growth	growth	NOUN
ctmj-188	172	72	process	process	NOUN
ctmj-188	172	73	of	of	ADP
ctmj-188	172	74	hct-8	hct-8	PUNCT
ctmj-188	172	75	cells	cell	NOUN
ctmj-188	172	76	by	by	ADP
ctmj-188	172	77	regulating	regulate	VERB
ctmj-188	172	78	the	the	DET
ctmj-188	172	79	pi3k	pi3k	PROPN
ctmj-188	172	80	/	/	SYM
ctmj-188	172	81	akt	akt	PROPN
ctmj-188	172	82	pathway	pathway	NOUN
ctmj-188	172	83	.	.	PUNCT
ctmj-188	173	1	discussion	discussion	NOUN
ctmj-188	173	2	crc	crc	NOUN
ctmj-188	173	3	ranks	rank	VERB
ctmj-188	173	4	as	as	ADP
ctmj-188	173	5	the	the	DET
ctmj-188	173	6	third	third	ADJ
ctmj-188	173	7	most	most	ADV
ctmj-188	173	8	common	common	ADJ
ctmj-188	173	9	malignant	malignant	ADJ
ctmj-188	173	10	tumor	tumor	NOUN
ctmj-188	173	11	in	in	ADP
ctmj-188	173	12	the	the	DET
ctmj-188	173	13	world.[1	world.[1	NOUN
ctmj-188	173	14	]	]	X
ctmj-188	173	15	current	current	ADJ
ctmj-188	173	16	treatment	treatment	NOUN
ctmj-188	173	17	choices	choice	NOUN
ctmj-188	173	18	for	for	ADP
ctmj-188	173	19	crc	crc	NOUN
ctmj-188	173	20	primarily	primarily	ADV
ctmj-188	173	21	include	include	VERB
ctmj-188	173	22	surgery	surgery	NOUN
ctmj-188	173	23	,	,	PUNCT
ctmj-188	173	24	radiotherapy	radiotherapy	NOUN
ctmj-188	173	25	and	and	CCONJ
ctmj-188	173	26	chemotherapy	chemotherapy	NOUN
ctmj-188	173	27	,	,	PUNCT
ctmj-188	173	28	with	with	ADP
ctmj-188	173	29	chemotherapy	chemotherapy	NOUN
ctmj-188	173	30	being	be	AUX
ctmj-188	173	31	the	the	DET
ctmj-188	173	32	main	main	ADJ
ctmj-188	173	33	approach	approach	NOUN
ctmj-188	173	34	for	for	ADP
ctmj-188	173	35	patients	patient	NOUN
ctmj-188	173	36	with	with	ADP
ctmj-188	173	37	inoperable	inoperable	ADJ
ctmj-188	173	38	or	or	CCONJ
ctmj-188	173	39	postoperative	postoperative	ADJ
ctmj-188	173	40	metastatic	metastatic	ADJ
ctmj-188	173	41	tumors.[2	tumors.[2	NOUN
ctmj-188	173	42	]	]	PUNCT
ctmj-188	174	1	5‑fu	5‑fu	NUM
ctmj-188	174	2	,	,	PUNCT
ctmj-188	174	3	the	the	DET
ctmj-188	174	4	first‑line	first‑line	NOUN
ctmj-188	174	5	chemotherapy	chemotherapy	NOUN
ctmj-188	174	6	regimen	regiman	NOUN
ctmj-188	174	7	,	,	PUNCT
ctmj-188	174	8	is	be	AUX
ctmj-188	174	9	widely	widely	ADV
ctmj-188	174	10	used	use	VERB
ctmj-188	174	11	in	in	ADP
ctmj-188	174	12	crc	crc	PROPN
ctmj-188	174	13	.	.	PUNCT
ctmj-188	175	1	however	however	ADV
ctmj-188	175	2	,	,	PUNCT
ctmj-188	175	3	the	the	DET
ctmj-188	175	4	side	side	NOUN
ctmj-188	175	5	effects	effect	NOUN
ctmj-188	175	6	which	which	PRON
ctmj-188	175	7	can	can	AUX
ctmj-188	175	8	easily	easily	ADV
ctmj-188	175	9	damage	damage	VERB
ctmj-188	175	10	the	the	DET
ctmj-188	175	11	normal	normal	ADJ
ctmj-188	175	12	organism	organism	NOUN
ctmj-188	175	13	,	,	PUNCT
ctmj-188	175	14	induce	induce	VERB
ctmj-188	175	15	drug	drug	NOUN
ctmj-188	175	16	resistance	resistance	NOUN
ctmj-188	175	17	and	and	CCONJ
ctmj-188	175	18	reduce	reduce	VERB
ctmj-188	175	19	patients	patient	NOUN
ctmj-188	175	20	’	'	PUNCT
ctmj-188	175	21	quality	quality	NOUN
ctmj-188	175	22	of	of	ADP
ctmj-188	175	23	life	life	NOUN
ctmj-188	175	24	limited	limit	VERB
ctmj-188	175	25	the	the	DET
ctmj-188	175	26	use	use	NOUN
ctmj-188	175	27	of	of	ADP
ctmj-188	175	28	5‑fu	5‑fu	PROPN
ctmj-188	175	29	.	.	PUNCT
ctmj-188	176	1	consequently	consequently	ADV
ctmj-188	176	2	,	,	PUNCT
ctmj-188	176	3	it	it	PRON
ctmj-188	176	4	is	be	AUX
ctmj-188	176	5	urgent	urgent	ADJ
ctmj-188	176	6	to	to	PART
ctmj-188	176	7	discover	discover	VERB
ctmj-188	176	8	novel	novel	ADJ
ctmj-188	176	9	treatment	treatment	NOUN
ctmj-188	176	10	strategies	strategy	NOUN
ctmj-188	176	11	to	to	PART
ctmj-188	176	12	overcome	overcome	VERB
ctmj-188	176	13	the	the	DET
ctmj-188	176	14	limitations	limitation	NOUN
ctmj-188	176	15	associated	associate	VERB
ctmj-188	176	16	with	with	ADP
ctmj-188	176	17	chemotherapy	chemotherapy	NOUN
ctmj-188	176	18	.	.	PUNCT
ctmj-188	177	1	combination	combination	NOUN
ctmj-188	177	2	therapy	therapy	NOUN
ctmj-188	177	3	involving	involve	VERB
ctmj-188	177	4	the	the	DET
ctmj-188	177	5	simultaneous	simultaneous	ADJ
ctmj-188	177	6	administration	administration	NOUN
ctmj-188	177	7	of	of	ADP
ctmj-188	177	8	multiple	multiple	ADJ
ctmj-188	177	9	drugs	drug	NOUN
ctmj-188	177	10	has	have	AUX
ctmj-188	177	11	emerged	emerge	VERB
ctmj-188	177	12	as	as	ADP
ctmj-188	177	13	a	a	DET
ctmj-188	177	14	promising	promising	ADJ
ctmj-188	177	15	approach	approach	NOUN
ctmj-188	177	16	.	.	PUNCT
ctmj-188	178	1	traditional	traditional	ADJ
ctmj-188	178	2	chinese	chinese	ADJ
ctmj-188	178	3	medicine	medicine	NOUN
ctmj-188	178	4	has	have	VERB
ctmj-188	178	5	better	well	ADJ
ctmj-188	178	6	advantages	advantage	NOUN
ctmj-188	178	7	in	in	ADP
ctmj-188	178	8	reducing	reduce	VERB
ctmj-188	178	9	toxicity	toxicity	NOUN
ctmj-188	178	10	and	and	CCONJ
ctmj-188	178	11	increasing	increase	VERB
ctmj-188	178	12	efficacy	efficacy	NOUN
ctmj-188	178	13	,	,	PUNCT
ctmj-188	178	14	combination	combination	NOUN
ctmj-188	178	15	therapy	therapy	NOUN
ctmj-188	178	16	of	of	ADP
ctmj-188	178	17	tcm	tcm	PROPN
ctmj-188	178	18	and	and	CCONJ
ctmj-188	178	19	5‑fu	5‑fu	VERB
ctmj-188	178	20	not	not	PART
ctmj-188	178	21	only	only	ADV
ctmj-188	178	22	increase	increase	VERB
ctmj-188	178	23	the	the	DET
ctmj-188	178	24	therapeutic	therapeutic	ADJ
ctmj-188	178	25	effects	effect	NOUN
ctmj-188	178	26	,	,	PUNCT
ctmj-188	178	27	but	but	CCONJ
ctmj-188	178	28	alleviate	alleviate	VERB
ctmj-188	178	29	the	the	DET
ctmj-188	178	30	side	side	NOUN
ctmj-188	178	31	effects	effect	NOUN
ctmj-188	178	32	at	at	ADP
ctmj-188	178	33	lower	low	ADJ
ctmj-188	178	34	dose	dose	PROPN
ctmj-188	178	35	.	.	PUNCT
ctmj-188	179	1	this	this	DET
ctmj-188	179	2	a	a	DET
ctmj-188	179	3	c	c	NOUN
ctmj-188	179	4	b	b	PROPN
ctmj-188	179	5	d	d	X
ctmj-188	179	6	f	f	PROPN
ctmj-188	179	7	e	e	PROPN
ctmj-188	179	8	51	51	NUM
ctmj-188	179	9	ctmj	ctmj	NOUN
ctmj-188	179	10	|	|	ADV
ctmj-188	179	11	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	179	12	chinese	chinese	ADJ
ctmj-188	179	13	traditional	traditional	ADJ
ctmj-188	179	14	medicine	medicine	NOUN
ctmj-188	179	15	journal	journal	NOUN
ctmj-188	179	16	|	|	ADV
ctmj-188	179	17	2025	2025	NUM
ctmj-188	179	18	|	|	ADV
ctmj-188	179	19	vol	vol	NOUN
ctmj-188	179	20	8	8	NUM
ctmj-188	179	21	|issue	|issue	NOUN
ctmj-188	179	22	1	1	NUM
ctmj-188	179	23	51	51	NUM
ctmj-188	179	24	figure	figure	NOUN
ctmj-188	179	25	5	5	NUM
ctmj-188	179	26	:	:	PUNCT
ctmj-188	179	27	qingjie	qingjie	NOUN
ctmj-188	179	28	fuzheng	fuzheng	PROPN
ctmj-188	179	29	granule	granule	PROPN
ctmj-188	179	30	combined	combine	VERB
ctmj-188	179	31	with	with	ADP
ctmj-188	179	32	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	179	33	synergisticly	synergisticly	ADV
ctmj-188	179	34	promoted	promote	VERB
ctmj-188	179	35	apoptosis	apoptosis	NOUN
ctmj-188	179	36	in	in	ADP
ctmj-188	179	37	xenograft	xenograft	NOUN
ctmj-188	179	38	mice	mouse	NOUN
ctmj-188	179	39	.	.	PUNCT
ctmj-188	180	1	(	(	PUNCT
ctmj-188	180	2	a	a	PRON
ctmj-188	180	3	and	and	CCONJ
ctmj-188	180	4	b	b	NOUN
ctmj-188	180	5	)	)	PUNCT
ctmj-188	180	6	tunel	tunel	NOUN
ctmj-188	180	7	staining	stain	VERB
ctmj-188	180	8	assay	assay	NOUN
ctmj-188	180	9	(	(	PUNCT
ctmj-188	180	10	×400	×400	NOUN
ctmj-188	180	11	,	,	PUNCT
ctmj-188	180	12	bar	bar	NOUN
ctmj-188	180	13	=	=	PUNCT
ctmj-188	180	14	50	50	NUM
ctmj-188	180	15	m	m	NOUN
ctmj-188	180	16	)	)	PUNCT
ctmj-188	180	17	.	.	PUNCT
ctmj-188	181	1	(	(	PUNCT
ctmj-188	181	2	c	c	NOUN
ctmj-188	181	3	and	and	CCONJ
ctmj-188	181	4	d	d	X
ctmj-188	181	5	)	)	PUNCT
ctmj-188	181	6	the	the	DET
ctmj-188	181	7	expression	expression	NOUN
ctmj-188	181	8	of	of	ADP
ctmj-188	181	9	apoptosis‑related	apoptosis‑relate	VERB
ctmj-188	181	10	proteins	protein	NOUN
ctmj-188	181	11	in	in	ADP
ctmj-188	181	12	xenograft	xenograft	NOUN
ctmj-188	181	13	tissues	tissue	NOUN
ctmj-188	181	14	.	.	PUNCT
ctmj-188	182	1	qfg	qfg	PROPN
ctmj-188	182	2	:	:	PUNCT
ctmj-188	182	3	qingjie	qingjie	PROPN
ctmj-188	182	4	fuzheng	fuzheng	PROPN
ctmj-188	182	5	granule	granule	PROPN
ctmj-188	182	6	,	,	PUNCT
ctmj-188	182	7	5‑fu	5‑fu	NUM
ctmj-188	182	8	:	:	PUNCT
ctmj-188	182	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	182	10	approach	approach	NOUN
ctmj-188	182	11	aims	aim	VERB
ctmj-188	182	12	to	to	PART
ctmj-188	182	13	achieve	achieve	VERB
ctmj-188	182	14	synergistic	synergistic	ADJ
ctmj-188	182	15	efficacy	efficacy	NOUN
ctmj-188	182	16	while	while	SCONJ
ctmj-188	182	17	reducing	reduce	VERB
ctmj-188	182	18	toxicity.[12	toxicity.[12	NOUN
ctmj-188	182	19	]	]	PUNCT
ctmj-188	182	20	patients	patient	NOUN
ctmj-188	182	21	'	'	PART
ctmj-188	182	22	quality	quality	NOUN
ctmj-188	182	23	of	of	ADP
ctmj-188	182	24	life	life	NOUN
ctmj-188	182	25	and	and	CCONJ
ctmj-188	182	26	chemotherapy	chemotherapy	NOUN
ctmj-188	182	27	effectiveness	effectiveness	NOUN
ctmj-188	182	28	are	be	AUX
ctmj-188	182	29	both	both	PRON
ctmj-188	182	30	improved	improve	VERB
ctmj-188	182	31	greatly	greatly	ADV
ctmj-188	182	32	by	by	ADP
ctmj-188	182	33	qfg	qfg	PROPN
ctmj-188	182	34	,	,	PUNCT
ctmj-188	182	35	a	a	DET
ctmj-188	182	36	clinical	clinical	ADJ
ctmj-188	182	37	anti	anti	ADJ
ctmj-188	182	38	-	-	ADJ
ctmj-188	182	39	tumor	tumor	ADJ
ctmj-188	182	40	compound	compound	NOUN
ctmj-188	182	41	that	that	PRON
ctmj-188	182	42	is	be	AUX
ctmj-188	182	43	often	often	ADV
ctmj-188	182	44	utilized	utilize	VERB
ctmj-188	182	45	.	.	PUNCT
ctmj-188	183	1	to	to	PART
ctmj-188	183	2	add	add	VERB
ctmj-188	183	3	to	to	ADP
ctmj-188	183	4	that	that	PRON
ctmj-188	183	5	,	,	PUNCT
ctmj-188	183	6	qfg	qfg	NOUN
ctmj-188	183	7	may	may	AUX
ctmj-188	183	8	shield	shield	VERB
ctmj-188	183	9	the	the	DET
ctmj-188	183	10	gut	gut	NOUN
ctmj-188	183	11	mucosal	mucosal	NOUN
ctmj-188	183	12	from	from	ADP
ctmj-188	183	13	5	5	NUM
ctmj-188	183	14	-	-	PUNCT
ctmj-188	183	15	fu	fu	NOUN
ctmj-188	183	16	.	.	PUNCT
ctmj-188	184	1	references	reference	NOUN
ctmj-188	185	1	[	[	X
ctmj-188	185	2	13,14	13,14	NUM
ctmj-188	185	3	]	]	PUNCT
ctmj-188	185	4	:	:	PUNCT
ctmj-188	185	5	it	it	PRON
ctmj-188	185	6	was	be	AUX
ctmj-188	185	7	proposed	propose	VERB
ctmj-188	185	8	that	that	SCONJ
ctmj-188	185	9	there	there	PRON
ctmj-188	185	10	could	could	AUX
ctmj-188	185	11	be	be	AUX
ctmj-188	185	12	a	a	DET
ctmj-188	185	13	synergistic	synergistic	ADJ
ctmj-188	185	14	impact	impact	NOUN
ctmj-188	185	15	when	when	SCONJ
ctmj-188	185	16	qfg	qfg	NOUN
ctmj-188	185	17	and	and	CCONJ
ctmj-188	185	18	5	5	NUM
ctmj-188	185	19	-	-	PUNCT
ctmj-188	185	20	fu	fu	NOUN
ctmj-188	185	21	are	be	AUX
ctmj-188	185	22	combined	combine	VERB
ctmj-188	185	23	.	.	PUNCT
ctmj-188	186	1	prior	prior	ADJ
ctmj-188	186	2	research	research	NOUN
ctmj-188	186	3	has	have	AUX
ctmj-188	186	4	shown	show	VERB
ctmj-188	186	5	that	that	SCONJ
ctmj-188	186	6	qfg	qfg	NOUN
ctmj-188	186	7	may	may	AUX
ctmj-188	186	8	control	control	VERB
ctmj-188	186	9	crc	crc	NOUN
ctmj-188	186	10	development	development	NOUN
ctmj-188	186	11	by	by	ADP
ctmj-188	186	12	inhibiting	inhibit	VERB
ctmj-188	186	13	the	the	DET
ctmj-188	186	14	pi3k	pi3k	PROPN
ctmj-188	186	15	/	/	SYM
ctmj-188	186	16	akt	akt	PROPN
ctmj-188	186	17	pathway	pathway	NOUN
ctmj-188	186	18	.	.	PUNCT
ctmj-188	187	1	[	[	X
ctmj-188	187	2	13	13	NUM
ctmj-188	187	3	]	]	PUNCT
ctmj-188	187	4	multiple	multiple	ADJ
ctmj-188	187	5	processes	process	NOUN
ctmj-188	187	6	,	,	PUNCT
ctmj-188	187	7	including	include	VERB
ctmj-188	187	8	tumor	tumor	NOUN
ctmj-188	187	9	growth	growth	NOUN
ctmj-188	187	10	,	,	PUNCT
ctmj-188	187	11	apoptosis	apoptosis	NOUN
ctmj-188	187	12	,	,	PUNCT
ctmj-188	187	13	metastasis	metastasis	NOUN
ctmj-188	187	14	,	,	PUNCT
ctmj-188	187	15	and	and	CCONJ
ctmj-188	187	16	resistance	resistance	NOUN
ctmj-188	187	17	to	to	ADP
ctmj-188	187	18	5	5	NUM
ctmj-188	187	19	-	-	PUNCT
ctmj-188	187	20	fu	fu	NOUN
ctmj-188	187	21	treatment	treatment	NOUN
ctmj-188	187	22	,	,	PUNCT
ctmj-188	187	23	are	be	AUX
ctmj-188	187	24	influenced	influence	VERB
ctmj-188	187	25	by	by	ADP
ctmj-188	187	26	the	the	DET
ctmj-188	187	27	tumor	tumor	NOUN
ctmj-188	187	28	-	-	PUNCT
ctmj-188	187	29	related	relate	VERB
ctmj-188	187	30	genes	gene	NOUN
ctmj-188	187	31	that	that	PRON
ctmj-188	187	32	are	be	AUX
ctmj-188	187	33	downstream	downstream	ADJ
ctmj-188	187	34	targets	target	NOUN
ctmj-188	187	35	of	of	ADP
ctmj-188	187	36	the	the	DET
ctmj-188	187	37	pi3k	pi3k	PROPN
ctmj-188	187	38	/	/	SYM
ctmj-188	187	39	akt	akt	PROPN
ctmj-188	187	40	signaling	signal	VERB
ctmj-188	187	41	pathway	pathway	NOUN
ctmj-188	187	42	.	.	PUNCT
ctmj-188	188	1	these	these	DET
ctmj-188	188	2	genes	gene	NOUN
ctmj-188	188	3	include	include	VERB
ctmj-188	188	4	p21	p21	NOUN
ctmj-188	188	5	,	,	PUNCT
ctmj-188	188	6	bcl-2	bcl-2	NOUN
ctmj-188	188	7	,	,	PUNCT
ctmj-188	188	8	emt	emt	PROPN
ctmj-188	188	9	,	,	PUNCT
ctmj-188	188	10	dpd	dpd	PROPN
ctmj-188	188	11	,	,	PUNCT
ctmj-188	188	12	ts	ts	NOUN
ctmj-188	188	13	,	,	PUNCT
ctmj-188	188	14	and	and	CCONJ
ctmj-188	188	15	others	other	NOUN
ctmj-188	188	16	.	.	PUNCT
ctmj-188	189	1	on	on	ADP
ctmj-188	189	2	the	the	DET
ctmj-188	189	3	basis	basis	NOUN
ctmj-188	189	4	of	of	ADP
ctmj-188	189	5	these	these	DET
ctmj-188	189	6	results	result	NOUN
ctmj-188	189	7	,	,	PUNCT
ctmj-188	189	8	the	the	DET
ctmj-188	189	9	purpose	purpose	NOUN
ctmj-188	189	10	of	of	ADP
ctmj-188	189	11	this	this	DET
ctmj-188	189	12	research	research	NOUN
ctmj-188	189	13	is	be	AUX
ctmj-188	189	14	to	to	PART
ctmj-188	189	15	investigate	investigate	VERB
ctmj-188	189	16	the	the	DET
ctmj-188	189	17	combined	combine	VERB
ctmj-188	189	18	effects	effect	NOUN
ctmj-188	189	19	of	of	ADP
ctmj-188	189	20	qfg	qfg	NOUN
ctmj-188	189	21	and	and	CCONJ
ctmj-188	189	22	5	5	NUM
ctmj-188	189	23	-	-	PUNCT
ctmj-188	189	24	fu	fu	NOUN
ctmj-188	189	25	on	on	ADP
ctmj-188	189	26	colorectal	colorectal	ADJ
ctmj-188	189	27	cancer	cancer	NOUN
ctmj-188	189	28	.	.	PUNCT
ctmj-188	190	1	furthermore	furthermore	ADV
ctmj-188	190	2	,	,	PUNCT
ctmj-188	190	3	we	we	PRON
ctmj-188	190	4	endeavored	endeavor	VERB
ctmj-188	190	5	to	to	PART
ctmj-188	190	6	investigate	investigate	VERB
ctmj-188	190	7	how	how	SCONJ
ctmj-188	190	8	qfg	qfg	ADJ
ctmj-188	190	9	and	and	CCONJ
ctmj-188	190	10	5	5	NUM
ctmj-188	190	11	-	-	PUNCT
ctmj-188	190	12	fu	fu	NOUN
ctmj-188	190	13	impacted	impact	VERB
ctmj-188	190	14	the	the	DET
ctmj-188	190	15	pi3k	pi3k	PROPN
ctmj-188	190	16	/	/	SYM
ctmj-188	190	17	akt	akt	PROPN
ctmj-188	190	18	pathway	pathway	NOUN
ctmj-188	190	19	and	and	CCONJ
ctmj-188	190	20	its	its	PRON
ctmj-188	190	21	subsequent	subsequent	ADJ
ctmj-188	190	22	processes	process	NOUN
ctmj-188	190	23	,	,	PUNCT
ctmj-188	190	24	such	such	ADJ
ctmj-188	190	25	as	as	ADP
ctmj-188	190	26	crc	crc	NOUN
ctmj-188	190	27	cell	cell	NOUN
ctmj-188	190	28	proliferation	proliferation	NOUN
ctmj-188	190	29	,	,	PUNCT
ctmj-188	190	30	apoptosis	apoptosis	NOUN
ctmj-188	190	31	,	,	PUNCT
ctmj-188	190	32	metastasis	metastasis	NOUN
ctmj-188	190	33	,	,	PUNCT
ctmj-188	190	34	and	and	CCONJ
ctmj-188	190	35	chemoresistance	chemoresistance	NOUN
ctmj-188	190	36	.	.	PUNCT
ctmj-188	191	1	understanding	understand	VERB
ctmj-188	191	2	how	how	SCONJ
ctmj-188	191	3	qfg	qfg	ADJ
ctmj-188	191	4	and	and	CCONJ
ctmj-188	191	5	5	5	NUM
ctmj-188	191	6	-	-	PUNCT
ctmj-188	191	7	fu	fu	NOUN
ctmj-188	191	8	work	work	NOUN
ctmj-188	191	9	together	together	ADV
ctmj-188	191	10	to	to	PART
ctmj-188	191	11	combat	combat	VERB
ctmj-188	191	12	crc	crc	NOUN
ctmj-188	191	13	is	be	AUX
ctmj-188	191	14	the	the	DET
ctmj-188	191	15	objective	objective	NOUN
ctmj-188	191	16	.	.	PUNCT
ctmj-188	192	1	the	the	DET
ctmj-188	192	2	unending	unending	ADJ
ctmj-188	192	3	advancement	advancement	NOUN
ctmj-188	192	4	of	of	ADP
ctmj-188	192	5	tumors	tumor	NOUN
ctmj-188	192	6	is	be	AUX
ctmj-188	192	7	mostly	mostly	ADV
ctmj-188	192	8	due	due	ADJ
ctmj-188	192	9	to	to	ADP
ctmj-188	192	10	the	the	DET
ctmj-188	192	11	unchecked	unchecked	ADJ
ctmj-188	192	12	growth	growth	NOUN
ctmj-188	192	13	of	of	ADP
ctmj-188	192	14	malignant	malignant	ADJ
ctmj-188	192	15	cells	cell	NOUN
ctmj-188	192	16	.	.	PUNCT
ctmj-188	193	1	[	[	X
ctmj-188	193	2	16	16	NUM
ctmj-188	193	3	]	]	PUNCT
ctmj-188	193	4	as	as	ADP
ctmj-188	193	5	a	a	DET
ctmj-188	193	6	crucial	crucial	ADJ
ctmj-188	193	7	tumor	tumor	NOUN
ctmj-188	193	8	suppressor	suppressor	NOUN
ctmj-188	193	9	and	and	CCONJ
ctmj-188	193	10	one	one	NUM
ctmj-188	193	11	of	of	ADP
ctmj-188	193	12	the	the	DET
ctmj-188	193	13	major	major	ADJ
ctmj-188	193	14	regulators	regulator	NOUN
ctmj-188	193	15	of	of	ADP
ctmj-188	193	16	cell	cell	NOUN
ctmj-188	193	17	division	division	NOUN
ctmj-188	193	18	,	,	PUNCT
ctmj-188	193	19	p53	p53	NOUN
ctmj-188	193	20	is	be	AUX
ctmj-188	193	21	an	an	DET
ctmj-188	193	22	important	important	ADJ
ctmj-188	193	23	player	player	NOUN
ctmj-188	193	24	in	in	ADP
ctmj-188	193	25	the	the	DET
ctmj-188	193	26	field	field	NOUN
ctmj-188	193	27	.	.	PUNCT
ctmj-188	194	1	one	one	NUM
ctmj-188	194	2	gene	gene	NOUN
ctmj-188	194	3	that	that	PRON
ctmj-188	194	4	suppresses	suppress	VERB
ctmj-188	194	5	cell	cell	NOUN
ctmj-188	194	6	cycle	cycle	NOUN
ctmj-188	194	7	-	-	PUNCT
ctmj-188	194	8	dependent	dependent	ADJ
ctmj-188	194	9	protein	protein	NOUN
ctmj-188	194	10	kinases	kinase	NOUN
ctmj-188	194	11	is	be	AUX
ctmj-188	194	12	p21	p21	NOUN
ctmj-188	194	13	,	,	PUNCT
ctmj-188	194	14	which	which	PRON
ctmj-188	194	15	is	be	AUX
ctmj-188	194	16	a	a	DET
ctmj-188	194	17	downstream	downstream	ADJ
ctmj-188	194	18	gene	gene	NOUN
ctmj-188	194	19	of	of	ADP
ctmj-188	194	20	p53	p53	NOUN
ctmj-188	194	21	[	[	X
ctmj-188	194	22	17	17	NUM
ctmj-188	194	23	]	]	PUNCT
ctmj-188	194	24	.	.	PUNCT
ctmj-188	195	1	cyclin	cyclin	PROPN
ctmj-188	195	2	d1	d1	PROPN
ctmj-188	195	3	-	-	PUNCT
ctmj-188	195	4	cdk4	cdk4	NOUN
ctmj-188	195	5	is	be	AUX
ctmj-188	195	6	unable	unable	ADJ
ctmj-188	195	7	to	to	PART
ctmj-188	195	8	phosphorylate	phosphorylate	VERB
ctmj-188	195	9	rb	rb	NOUN
ctmj-188	195	10	(	(	PUNCT
ctmj-188	195	11	g1	g1	NOUN
ctmj-188	195	12	phase	phase	NOUN
ctmj-188	195	13	cycle	cycle	NOUN
ctmj-188	195	14	)	)	PUNCT
ctmj-188	195	15	because	because	SCONJ
ctmj-188	195	16	a	a	DET
ctmj-188	195	17	complex	complex	NOUN
ctmj-188	195	18	formed	form	VERB
ctmj-188	195	19	by	by	ADP
ctmj-188	195	20	p21	p21	PROPN
ctmj-188	195	21	and	and	CCONJ
ctmj-188	195	22	cyclin	cyclin	NOUN
ctmj-188	195	23	d1	d1	PROPN
ctmj-188	195	24	-	-	PUNCT
ctmj-188	195	25	cdk4	cdk4	NOUN
ctmj-188	195	26	suppresses	suppress	VERB
ctmj-188	195	27	protein	protein	NOUN
ctmj-188	195	28	kinase	kinase	NOUN
ctmj-188	195	29	activity	activity	NOUN
ctmj-188	195	30	.	.	PUNCT
ctmj-188	196	1	protein	protein	NOUN
ctmj-188	196	2	that	that	PRON
ctmj-188	196	3	acts	act	VERB
ctmj-188	196	4	as	as	ADP
ctmj-188	196	5	an	an	DET
ctmj-188	196	6	inhibitor	inhibitor	NOUN
ctmj-188	196	7	.	.	PUNCT
ctmj-188	197	1	the	the	DET
ctmj-188	197	2	g1	g1	PROPN
ctmj-188	197	3	phase	phase	NOUN
ctmj-188	197	4	block	block	NOUN
ctmj-188	197	5	and	and	CCONJ
ctmj-188	197	6	inhibition	inhibition	NOUN
ctmj-188	197	7	of	of	ADP
ctmj-188	197	8	cell	cell	NOUN
ctmj-188	197	9	proliferation	proliferation	NOUN
ctmj-188	197	10	are	be	AUX
ctmj-188	197	11	caused	cause	VERB
ctmj-188	197	12	by	by	ADP
ctmj-188	197	13	rb	rb	NOUN
ctmj-188	197	14	's	's	PART
ctmj-188	197	15	inactive	inactive	ADJ
ctmj-188	197	16	state	state	NOUN
ctmj-188	197	17	binding	bind	VERB
ctmj-188	197	18	to	to	ADP
ctmj-188	197	19	e2f	e2f	PROPN
ctmj-188	197	20	,	,	PUNCT
ctmj-188	197	21	which	which	PRON
ctmj-188	197	22	inactivates	inactivate	VERB
ctmj-188	197	23	e2f	e2f	PROPN
ctmj-188	197	24	.	.	PUNCT
ctmj-188	198	1	pp	pp	ADJ
ctmj-188	198	2	.	.	PUNCT
ctmj-188	199	1	18–21	18–21	NUM
ctmj-188	199	2	the	the	DET
ctmj-188	199	3	colony	colony	NOUN
ctmj-188	199	4	formation	formation	NOUN
ctmj-188	199	5	test	test	NOUN
ctmj-188	199	6	was	be	AUX
ctmj-188	199	7	used	use	VERB
ctmj-188	199	8	to	to	PART
ctmj-188	199	9	determine	determine	VERB
ctmj-188	199	10	that	that	SCONJ
ctmj-188	199	11	a	a	DET
ctmj-188	199	12	mixture	mixture	NOUN
ctmj-188	199	13	of	of	ADP
ctmj-188	199	14	qfg	qfg	NOUN
ctmj-188	199	15	and	and	CCONJ
ctmj-188	199	16	5	5	NUM
ctmj-188	199	17	-	-	PUNCT
ctmj-188	199	18	fu	fu	NOUN
ctmj-188	199	19	may	may	AUX
ctmj-188	199	20	decrease	decrease	VERB
ctmj-188	199	21	cell	cell	NOUN
ctmj-188	199	22	growth	growth	NOUN
ctmj-188	199	23	in	in	ADP
ctmj-188	199	24	this	this	DET
ctmj-188	199	25	investigation	investigation	NOUN
ctmj-188	199	26	.	.	PUNCT
ctmj-188	200	1	we	we	PRON
ctmj-188	200	2	found	find	VERB
ctmj-188	200	3	that	that	SCONJ
ctmj-188	200	4	the	the	DET
ctmj-188	200	5	combination	combination	NOUN
ctmj-188	200	6	of	of	ADP
ctmj-188	200	7	qfg	qfg	NOUN
ctmj-188	200	8	and	and	CCONJ
ctmj-188	200	9	5	5	NUM
ctmj-188	200	10	-	-	PUNCT
ctmj-188	200	11	fu	fu	NOUN
ctmj-188	200	12	decreased	decrease	VERB
ctmj-188	200	13	ki67	ki67	PROPN
ctmj-188	200	14	positivity	positivity	NOUN
ctmj-188	200	15	in	in	ADP
ctmj-188	200	16	tumor	tumor	NOUN
ctmj-188	200	17	tissues	tissue	NOUN
ctmj-188	200	18	by	by	ADP
ctmj-188	200	19	immunohistochemical	immunohistochemical	ADJ
ctmj-188	200	20	assay	assay	NOUN
ctmj-188	200	21	.	.	PUNCT
ctmj-188	201	1	we	we	PRON
ctmj-188	201	2	also	also	ADV
ctmj-188	201	3	found	find	VERB
ctmj-188	201	4	that	that	SCONJ
ctmj-188	201	5	the	the	DET
ctmj-188	201	6	combination	combination	NOUN
ctmj-188	201	7	of	of	ADP
ctmj-188	201	8	qfg	qfg	NOUN
ctmj-188	201	9	and	and	CCONJ
ctmj-188	201	10	5	5	NUM
ctmj-188	201	11	-	-	PUNCT
ctmj-188	201	12	fu	fu	NOUN
ctmj-188	201	13	increased	increase	VERB
ctmj-188	201	14	p53	p53	NOUN
ctmj-188	201	15	and	and	CCONJ
ctmj-188	201	16	p21	p21	NOUN
ctmj-188	201	17	protein	protein	NOUN
ctmj-188	201	18	expression	expression	NOUN
ctmj-188	201	19	while	while	SCONJ
ctmj-188	201	20	inhibiting	inhibit	VERB
ctmj-188	201	21	cyclin	cyclin	NOUN
ctmj-188	201	22	d1	d1	PROPN
ctmj-188	201	23	and	and	CCONJ
ctmj-188	201	24	cdk4	cdk4	VERB
ctmj-188	201	25	protein	protein	NOUN
ctmj-188	201	26	expression	expression	NOUN
ctmj-188	201	27	by	by	ADP
ctmj-188	201	28	western	western	ADJ
ctmj-188	201	29	bolt	bolt	NOUN
ctmj-188	201	30	assay	assay	VERB
ctmj-188	201	31	,	,	PUNCT
ctmj-188	201	32	compared	compare	VERB
ctmj-188	201	33	to	to	ADP
ctmj-188	201	34	single	single	ADJ
ctmj-188	201	35	drug	drug	NOUN
ctmj-188	201	36	.	.	PUNCT
ctmj-188	202	1	the	the	DET
ctmj-188	202	2	results	result	NOUN
ctmj-188	202	3	of	of	ADP
ctmj-188	202	4	the	the	DET
ctmj-188	202	5	experiment	experiment	NOUN
ctmj-188	202	6	show	show	VERB
ctmj-188	202	7	that	that	SCONJ
ctmj-188	202	8	it	it	PRON
ctmj-188	202	9	is	be	AUX
ctmj-188	202	10	possible	possible	ADJ
ctmj-188	202	11	to	to	PART
ctmj-188	202	12	suppress	suppress	VERB
ctmj-188	202	13	the	the	DET
ctmj-188	202	14	growth	growth	NOUN
ctmj-188	202	15	of	of	ADP
ctmj-188	202	16	colorectal	colorectal	ADJ
ctmj-188	202	17	cancer	cancer	NOUN
ctmj-188	202	18	cells	cell	NOUN
ctmj-188	202	19	by	by	ADP
ctmj-188	202	20	combining	combine	VERB
ctmj-188	202	21	qfg	qfg	NOUN
ctmj-188	202	22	with	with	ADP
ctmj-188	202	23	5	5	NUM
ctmj-188	202	24	-	-	PUNCT
ctmj-188	202	25	fu	fu	NOUN
ctmj-188	202	26	.	.	PUNCT
ctmj-188	203	1	the	the	DET
ctmj-188	203	2	process	process	NOUN
ctmj-188	203	3	of	of	ADP
ctmj-188	203	4	programmed	program	VERB
ctmj-188	203	5	cell	cell	NOUN
ctmj-188	203	6	death	death	NOUN
ctmj-188	203	7	,	,	PUNCT
ctmj-188	203	8	or	or	CCONJ
ctmj-188	203	9	apoptosis	apoptosis	NOUN
ctmj-188	203	10	,	,	PUNCT
ctmj-188	203	11	is	be	AUX
ctmj-188	203	12	controlled	control	VERB
ctmj-188	203	13	by	by	ADP
ctmj-188	203	14	genes	gene	NOUN
ctmj-188	203	15	and	and	CCONJ
ctmj-188	203	16	results	result	NOUN
ctmj-188	203	17	in	in	ADP
ctmj-188	203	18	the	the	DET
ctmj-188	203	19	inevitable	inevitable	ADJ
ctmj-188	203	20	cessation	cessation	NOUN
ctmj-188	203	21	of	of	ADP
ctmj-188	203	22	life	life	NOUN
ctmj-188	203	23	.	.	PUNCT
ctmj-188	204	1	[	[	X
ctmj-188	204	2	8	8	NUM
ctmj-188	204	3	]	]	PUNCT
ctmj-188	204	4	in	in	ADP
ctmj-188	204	5	apoptosis	apoptosis	NOUN
ctmj-188	204	6	,	,	PUNCT
ctmj-188	204	7	the	the	DET
ctmj-188	204	8	bcl-2	bcl-2	ADJ
ctmj-188	204	9	family	family	NOUN
ctmj-188	204	10	is	be	AUX
ctmj-188	204	11	involved	involve	VERB
ctmj-188	204	12	,	,	PUNCT
ctmj-188	204	13	and	and	CCONJ
ctmj-188	204	14	bax	bax	PROPN
ctmj-188	204	15	dimers	dimers	PROPN
ctmj-188	204	16	help	help	AUX
ctmj-188	204	17	open	open	VERB
ctmj-188	204	18	and	and	CCONJ
ctmj-188	204	19	increase	increase	VERB
ctmj-188	204	20	the	the	DET
ctmj-188	204	21	permeability	permeability	NOUN
ctmj-188	204	22	of	of	ADP
ctmj-188	204	23	the	the	DET
ctmj-188	204	24	mitochondrial	mitochondrial	ADJ
ctmj-188	204	25	membrane	membrane	NOUN
ctmj-188	204	26	.	.	PUNCT
ctmj-188	205	1	a	a	DET
ctmj-188	205	2	reduction	reduction	NOUN
ctmj-188	205	3	in	in	ADP
ctmj-188	205	4	mitochondrial	mitochondrial	ADJ
ctmj-188	205	5	membrane	membrane	NOUN
ctmj-188	205	6	permeability	permeability	NOUN
ctmj-188	205	7	follows	follow	VERB
ctmj-188	205	8	an	an	DET
ctmj-188	205	9	increase	increase	NOUN
ctmj-188	205	10	in	in	ADP
ctmj-188	205	11	bcl-2	bcl-2	NOUN
ctmj-188	205	12	expression	expression	NOUN
ctmj-188	205	13	,	,	PUNCT
ctmj-188	205	14	and	and	CCONJ
ctmj-188	205	15	bcl-2	bcl-2	NOUN
ctmj-188	205	16	may	may	AUX
ctmj-188	205	17	form	form	VERB
ctmj-188	205	18	heterodimers	heterodimer	NOUN
ctmj-188	205	19	with	with	ADP
ctmj-188	205	20	bax	bax	PROPN
ctmj-188	205	21	.	.	PROPN
ctmj-188	205	22	as	as	ADP
ctmj-188	205	23	a	a	DET
ctmj-188	205	24	result	result	NOUN
ctmj-188	205	25	,	,	PUNCT
ctmj-188	205	26	cystathionase	cystathionase	NOUN
ctmj-188	205	27	(	(	PUNCT
ctmj-188	205	28	caspases	caspase	NOUN
ctmj-188	205	29	)	)	PUNCT
ctmj-188	205	30	is	be	AUX
ctmj-188	205	31	activated	activate	VERB
ctmj-188	205	32	when	when	SCONJ
ctmj-188	205	33	cellular	cellular	ADJ
ctmj-188	205	34	mitochondrial	mitochondrial	ADJ
ctmj-188	205	35	membrane	membrane	NOUN
ctmj-188	205	36	disruption	disruption	NOUN
ctmj-188	205	37	triggers	trigger	VERB
ctmj-188	205	38	the	the	DET
ctmj-188	205	39	release	release	NOUN
ctmj-188	205	40	of	of	ADP
ctmj-188	205	41	cytochrome	cytochrome	NOUN
ctmj-188	205	42	-	-	PUNCT
ctmj-188	205	43	c.	c.	NOUN
ctmj-188	205	44	cell	cell	NOUN
ctmj-188	205	45	death	death	NOUN
ctmj-188	205	46	is	be	AUX
ctmj-188	205	47	orchestrated	orchestrate	VERB
ctmj-188	205	48	by	by	ADP
ctmj-188	205	49	these	these	DET
ctmj-188	205	50	cleaved	cleaved	ADJ
ctmj-188	205	51	caspases	caspase	NOUN
ctmj-188	205	52	,	,	PUNCT
ctmj-188	205	53	one	one	NUM
ctmj-188	205	54	of	of	ADP
ctmj-188	205	55	which	which	PRON
ctmj-188	205	56	being	be	AUX
ctmj-188	205	57	caspase	caspase	NOUN
ctmj-188	205	58	3	3	NUM
ctmj-188	206	1	.	.	PUNCT
ctmj-188	206	2	pages	page	NOUN
ctmj-188	207	1	22–24	22–24	NUM
ctmj-188	207	2	this	this	DET
ctmj-188	207	3	research	research	NOUN
ctmj-188	207	4	used	use	VERB
ctmj-188	207	5	a	a	DET
ctmj-188	207	6	battery	battery	NOUN
ctmj-188	207	7	of	of	ADP
ctmj-188	207	8	tests	test	NOUN
ctmj-188	207	9	,	,	PUNCT
ctmj-188	207	10	including	include	VERB
ctmj-188	207	11	western	western	ADJ
ctmj-188	207	12	blotting	blotting	NOUN
ctmj-188	207	13	,	,	PUNCT
ctmj-188	207	14	flow	flow	NOUN
ctmj-188	207	15	cytometry	cytometry	NOUN
ctmj-188	207	16	,	,	PUNCT
ctmj-188	207	17	dapi	dapi	ADJ
ctmj-188	207	18	staining	staining	NOUN
ctmj-188	207	19	,	,	PUNCT
ctmj-188	207	20	and	and	CCONJ
ctmj-188	207	21	tunel	tunel	NOUN
ctmj-188	207	22	immunofluorescence	immunofluorescence	NOUN
ctmj-188	207	23	,	,	PUNCT
ctmj-188	207	24	to	to	PART
ctmj-188	207	25	confirm	confirm	VERB
ctmj-188	207	26	elevated	elevated	ADJ
ctmj-188	207	27	apoptosis	apoptosis	NOUN
ctmj-188	207	28	.	.	PUNCT
ctmj-188	208	1	a	a	DET
ctmj-188	208	2	b	b	X
ctmj-188	208	3	c	c	NOUN
ctmj-188	208	4	d	d	SYM
ctmj-188	208	5	52	52	NUM
ctmj-188	208	6	ctmj	ctmj	NOUN
ctmj-188	208	7	|	|	ADV
ctmj-188	208	8	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	208	9	chinese	chinese	ADJ
ctmj-188	208	10	traditional	traditional	ADJ
ctmj-188	208	11	medicine	medicine	NOUN
ctmj-188	208	12	journal	journal	NOUN
ctmj-188	208	13	|	|	ADV
ctmj-188	208	14	2025	2025	NUM
ctmj-188	208	15	|	|	ADV
ctmj-188	208	16	vol	vol	NOUN
ctmj-188	208	17	8	8	NUM
ctmj-188	208	18	|issue	|issue	NOUN
ctmj-188	208	19	1	1	NUM
ctmj-188	208	20	52	52	NUM
ctmj-188	208	21	figure	figure	NOUN
ctmj-188	208	22	6	6	NUM
ctmj-188	208	23	:	:	PUNCT
ctmj-188	208	24	qingjie	qingjie	NOUN
ctmj-188	208	25	fuzheng	fuzheng	PROPN
ctmj-188	208	26	granule	granule	PROPN
ctmj-188	208	27	(	(	PUNCT
ctmj-188	208	28	qfg	qfg	ADJ
ctmj-188	208	29	)	)	PUNCT
ctmj-188	208	30	and	and	CCONJ
ctmj-188	208	31	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	208	32	(	(	PUNCT
ctmj-188	208	33	5‑fu	5‑fu	NOUN
ctmj-188	208	34	)	)	PUNCT
ctmj-188	208	35	inhibited	inhibit	VERB
ctmj-188	208	36	migration	migration	NOUN
ctmj-188	208	37	and	and	CCONJ
ctmj-188	208	38	invasion	invasion	NOUN
ctmj-188	208	39	.	.	PUNCT
ctmj-188	209	1	(	(	PUNCT
ctmj-188	209	2	a	a	DET
ctmj-188	209	3	and	and	CCONJ
ctmj-188	209	4	b	b	NOUN
ctmj-188	209	5	)	)	PUNCT
ctmj-188	209	6	migration	migration	NOUN
ctmj-188	209	7	assay	assay	NOUN
ctmj-188	209	8	and	and	CCONJ
ctmj-188	209	9	statistic	statistic	VERB
ctmj-188	209	10	analysis	analysis	NOUN
ctmj-188	209	11	in	in	ADP
ctmj-188	209	12	hct‑8	hct‑8	NOUN
ctmj-188	209	13	cells	cell	NOUN
ctmj-188	209	14	(	(	PUNCT
ctmj-188	209	15	×200	×200	PROPN
ctmj-188	209	16	,	,	PUNCT
ctmj-188	209	17	bar	bar	NOUN
ctmj-188	209	18	=	=	PUNCT
ctmj-188	209	19	100	100	NUM
ctmj-188	209	20	m	m	NOUN
ctmj-188	209	21	)	)	PUNCT
ctmj-188	209	22	.	.	PUNCT
ctmj-188	210	1	(	(	PUNCT
ctmj-188	210	2	c	c	NOUN
ctmj-188	210	3	and	and	CCONJ
ctmj-188	210	4	d	d	NOUN
ctmj-188	210	5	)	)	PUNCT
ctmj-188	210	6	invasion	invasion	NOUN
ctmj-188	210	7	assay	assay	VERB
ctmj-188	210	8	and	and	CCONJ
ctmj-188	210	9	statistic	statistic	VERB
ctmj-188	210	10	analysis	analysis	NOUN
ctmj-188	210	11	in	in	ADP
ctmj-188	210	12	hct‑8	hct‑8	NOUN
ctmj-188	210	13	cells	cell	NOUN
ctmj-188	210	14	(	(	PUNCT
ctmj-188	210	15	×200	×200	PROPN
ctmj-188	210	16	,	,	PUNCT
ctmj-188	210	17	bar	bar	NOUN
ctmj-188	210	18	=	=	PUNCT
ctmj-188	210	19	100	100	NUM
ctmj-188	210	20	m	m	NOUN
ctmj-188	210	21	)	)	PUNCT
ctmj-188	210	22	.	.	PUNCT
ctmj-188	211	1	(	(	PUNCT
ctmj-188	211	2	e	e	NOUN
ctmj-188	211	3	and	and	CCONJ
ctmj-188	211	4	f	f	X
ctmj-188	211	5	)	)	PUNCT
ctmj-188	211	6	emt‑related	emt‑relate	VERB
ctmj-188	211	7	proteins	protein	NOUN
ctmj-188	211	8	expression	expression	NOUN
ctmj-188	211	9	in	in	ADP
ctmj-188	211	10	hct‑8	hct‑8	NOUN
ctmj-188	211	11	cells	cell	NOUN
ctmj-188	211	12	.	.	PUNCT
ctmj-188	212	1	(	(	PUNCT
ctmj-188	212	2	g	g	NOUN
ctmj-188	212	3	and	and	CCONJ
ctmj-188	212	4	h	h	NOUN
ctmj-188	212	5	)	)	PUNCT
ctmj-188	212	6	emt‑related	emt‑relate	VERB
ctmj-188	212	7	proteins	protein	NOUN
ctmj-188	212	8	expression	expression	NOUN
ctmj-188	212	9	in	in	ADP
ctmj-188	212	10	xenograft	xenograft	NOUN
ctmj-188	212	11	mice	mouse	NOUN
ctmj-188	212	12	.	.	PUNCT
ctmj-188	213	1	*	*	PUNCT
ctmj-188	213	2	p	p	X
ctmj-188	213	3	<	<	X
ctmj-188	213	4	0.05	0.05	NUM
ctmj-188	213	5	compared	compare	VERB
ctmj-188	213	6	to	to	ADP
ctmj-188	213	7	the	the	DET
ctmj-188	213	8	control	control	NOUN
ctmj-188	213	9	group	group	NOUN
ctmj-188	213	10	;	;	PUNCT
ctmj-188	213	11	^	^	PUNCT
ctmj-188	213	12	p	p	X
ctmj-188	213	13	<	<	X
ctmj-188	213	14	0.05	0.05	NUM
ctmj-188	213	15	compared	compare	VERB
ctmj-188	213	16	to	to	ADP
ctmj-188	213	17	the	the	DET
ctmj-188	213	18	qfg	qfg	ADJ
ctmj-188	213	19	group	group	NOUN
ctmj-188	213	20	;	;	PUNCT
ctmj-188	213	21	#	#	SYM
ctmj-188	213	22	p	p	X
ctmj-188	213	23	<	<	X
ctmj-188	213	24	0.05	0.05	NUM
ctmj-188	213	25	compared	compare	VERB
ctmj-188	213	26	to	to	ADP
ctmj-188	213	27	the	the	DET
ctmj-188	213	28	5‑fu	5‑fu	PROPN
ctmj-188	213	29	group	group	NOUN
ctmj-188	213	30	.	.	PUNCT
ctmj-188	214	1	qfg	qfg	PROPN
ctmj-188	214	2	:	:	PUNCT
ctmj-188	214	3	qingjie	qingjie	PROPN
ctmj-188	214	4	fuzheng	fuzheng	PROPN
ctmj-188	214	5	granule	granule	PROPN
ctmj-188	214	6	,	,	PUNCT
ctmj-188	214	7	5‑fu	5‑fu	NUM
ctmj-188	214	8	:	:	PUNCT
ctmj-188	214	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	214	10	emt	emt	PROPN
ctmj-188	214	11	is	be	AUX
ctmj-188	214	12	a	a	DET
ctmj-188	214	13	process	process	NOUN
ctmj-188	214	14	in	in	ADP
ctmj-188	214	15	which	which	PRON
ctmj-188	214	16	epithelial	epithelial	ADJ
ctmj-188	214	17	cell	cell	NOUN
ctmj-188	214	18	phenotype	phenotype	NOUN
ctmj-188	214	19	transformed	transform	VERB
ctmj-188	214	20	to	to	ADP
ctmj-188	214	21	mesenchymal	mesenchymal	ADJ
ctmj-188	214	22	cell	cell	NOUN
ctmj-188	214	23	phenotype	phenotype	NOUN
ctmj-188	214	24	under	under	ADP
ctmj-188	214	25	specific	specific	ADJ
ctmj-188	214	26	physiological	physiological	ADJ
ctmj-188	214	27	or	or	CCONJ
ctmj-188	214	28	pathological	pathological	ADJ
ctmj-188	214	29	conditions	condition	NOUN
ctmj-188	214	30	,	,	PUNCT
ctmj-188	214	31	which	which	PRON
ctmj-188	214	32	promotes	promote	VERB
ctmj-188	214	33	the	the	DET
ctmj-188	214	34	loss	loss	NOUN
ctmj-188	214	35	of	of	ADP
ctmj-188	214	36	intercellular	intercellular	ADJ
ctmj-188	214	37	adhesions	adhesion	NOUN
ctmj-188	214	38	,	,	PUNCT
ctmj-188	214	39	increases	increase	VERB
ctmj-188	214	40	the	the	DET
ctmj-188	214	41	metastatic	metastatic	ADJ
ctmj-188	214	42	capacity	capacity	NOUN
ctmj-188	214	43	of	of	ADP
ctmj-188	214	44	cancer	cancer	NOUN
ctmj-188	214	45	cells	cell	NOUN
ctmj-188	214	46	,	,	PUNCT
ctmj-188	214	47	inhibits	inhibit	VERB
ctmj-188	214	48	apoptosis	apoptosis	NOUN
ctmj-188	214	49	,	,	PUNCT
ctmj-188	214	50	and	and	CCONJ
ctmj-188	214	51	is	be	AUX
ctmj-188	214	52	an	an	DET
ctmj-188	214	53	important	important	ADJ
ctmj-188	214	54	factor	factor	NOUN
ctmj-188	214	55	affecting	affect	VERB
ctmj-188	214	56	tumor	tumor	NOUN
ctmj-188	214	57	recurrence	recurrence	NOUN
ctmj-188	214	58	and	and	CCONJ
ctmj-188	214	59	metastasis.[25	metastasis.[25	PROPN
ctmj-188	214	60	-	-	PUNCT
ctmj-188	214	61	28	28	NUM
ctmj-188	214	62	]	]	PUNCT
ctmj-188	214	63	cell	cell	NOUN
ctmj-188	214	64	-	-	PUNCT
ctmj-188	214	65	triggered	trigger	VERB
ctmj-188	214	66	emt	emt	PROPN
ctmj-188	214	67	,	,	PUNCT
ctmj-188	214	68	which	which	PRON
ctmj-188	214	69	results	result	VERB
ctmj-188	214	70	in	in	ADP
ctmj-188	214	71	loss	loss	NOUN
ctmj-188	214	72	of	of	ADP
ctmj-188	214	73	epithelial	epithelial	ADJ
ctmj-188	214	74	cell	cell	NOUN
ctmj-188	214	75	integrity	integrity	NOUN
ctmj-188	214	76	,	,	PUNCT
ctmj-188	214	77	and	and	CCONJ
ctmj-188	214	78	transcriptional	transcriptional	ADJ
ctmj-188	214	79	repression	repression	NOUN
ctmj-188	214	80	of	of	ADP
ctmj-188	214	81	genes	gene	NOUN
ctmj-188	214	82	encoding	encode	VERB
ctmj-188	214	83	epithelial	epithelial	ADJ
ctmj-188	214	84	cell	cell	NOUN
ctmj-188	214	85	-	-	PUNCT
ctmj-188	214	86	specific	specific	ADJ
ctmj-188	214	87	proteins	protein	NOUN
ctmj-188	214	88	such	such	ADJ
ctmj-188	214	89	as	as	ADP
ctmj-188	214	90	e	e	NOUN
ctmj-188	214	91	-	-	NOUN
ctmj-188	214	92	cadherin	cadherin	NOUN
ctmj-188	214	93	by	by	ADP
ctmj-188	214	94	transcription	transcription	NOUN
ctmj-188	214	95	factors	factor	NOUN
ctmj-188	214	96	,	,	PUNCT
ctmj-188	214	97	contribute	contribute	VERB
ctmj-188	214	98	to	to	ADP
ctmj-188	214	99	the	the	DET
ctmj-188	214	100	degradation	degradation	NOUN
ctmj-188	214	101	of	of	ADP
ctmj-188	214	102	adherens	adheren	NOUN
ctmj-188	214	103	junctions	junction	NOUN
ctmj-188	214	104	,	,	PUNCT
ctmj-188	214	105	and	and	CCONJ
ctmj-188	214	106	their	their	PRON
ctmj-188	214	107	adherens	adheren	NOUN
ctmj-188	214	108	junctions	junction	NOUN
ctmj-188	214	109	are	be	AUX
ctmj-188	214	110	replaced	replace	VERB
ctmj-188	214	111	by	by	ADP
ctmj-188	214	112	proteins	protein	NOUN
ctmj-188	214	113	capable	capable	ADJ
ctmj-188	214	114	of	of	ADP
ctmj-188	214	115	greater	great	ADJ
ctmj-188	214	116	junctional	junctional	ADJ
ctmj-188	214	117	flexibility	flexibility	NOUN
ctmj-188	214	118	(	(	PUNCT
ctmj-188	214	119	e.g.	e.g.	ADV
ctmj-188	214	120	,	,	PUNCT
ctmj-188	214	121	n‑cadherin	n‑cadherin	NOUN
ctmj-188	214	122	)	)	PUNCT
ctmj-188	214	123	,	,	PUNCT
ctmj-188	214	124	leading	lead	VERB
ctmj-188	214	125	to	to	ADP
ctmj-188	214	126	cell	cell	NOUN
ctmj-188	214	127	separation	separation	NOUN
ctmj-188	214	128	and	and	CCONJ
ctmj-188	214	129	enhanced	enhance	VERB
ctmj-188	214	130	cell	cell	NOUN
ctmj-188	214	131	motility.[29	motility.[29	NOUN
ctmj-188	214	132	-	-	PUNCT
ctmj-188	214	133	34	34	NUM
ctmj-188	214	134	]	]	PUNCT
ctmj-188	214	135	epithelial	epithelial	ADJ
ctmj-188	214	136	genes	gene	NOUN
ctmj-188	215	1	a	a	DET
ctmj-188	215	2	c	c	NOUN
ctmj-188	215	3	b	b	PROPN
ctmj-188	215	4	d	d	PROPN
ctmj-188	215	5	e	e	X
ctmj-188	215	6	f	f	PROPN
ctmj-188	215	7	g	g	PROPN
ctmj-188	215	8	h	h	PROPN
ctmj-188	215	9	53	53	NUM
ctmj-188	215	10	ctmj	ctmj	NOUN
ctmj-188	216	1	|	|	ADV
ctmj-188	216	2	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	216	3	chinese	chinese	ADJ
ctmj-188	216	4	traditional	traditional	ADJ
ctmj-188	216	5	medicine	medicine	NOUN
ctmj-188	216	6	journal	journal	NOUN
ctmj-188	216	7	|	|	ADV
ctmj-188	216	8	2025	2025	NUM
ctmj-188	216	9	|	|	ADV
ctmj-188	216	10	vol	vol	NOUN
ctmj-188	216	11	8	8	NUM
ctmj-188	216	12	|issue	|issue	NOUN
ctmj-188	216	13	1	1	NUM
ctmj-188	216	14	53	53	NUM
ctmj-188	216	15	figure	figure	NOUN
ctmj-188	216	16	7	7	NUM
ctmj-188	216	17	:	:	PUNCT
ctmj-188	216	18	qingjie	qingjie	NOUN
ctmj-188	216	19	fuzheng	fuzheng	PROPN
ctmj-188	216	20	granule	granule	PROPN
ctmj-188	216	21	(	(	PUNCT
ctmj-188	216	22	qfg	qfg	ADJ
ctmj-188	216	23	)	)	PUNCT
ctmj-188	216	24	and	and	CCONJ
ctmj-188	216	25	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	216	26	(	(	PUNCT
ctmj-188	216	27	5‑fu	5‑fu	PROPN
ctmj-188	216	28	)	)	PUNCT
ctmj-188	216	29	inhibited	inhibit	VERB
ctmj-188	216	30	dpd	dpd	NOUN
ctmj-188	216	31	and	and	CCONJ
ctmj-188	216	32	ts	ts	ADP
ctmj-188	216	33	expression	expression	NOUN
ctmj-188	216	34	.	.	PUNCT
ctmj-188	217	1	(	(	PUNCT
ctmj-188	217	2	a	a	PRON
ctmj-188	217	3	and	and	CCONJ
ctmj-188	217	4	b	b	NOUN
ctmj-188	217	5	)	)	PUNCT
ctmj-188	217	6	dpd	dpd	NOUN
ctmj-188	217	7	and	and	CCONJ
ctmj-188	217	8	ts	ts	ADP
ctmj-188	217	9	expression	expression	NOUN
ctmj-188	217	10	in	in	ADP
ctmj-188	217	11	hct‑8	hct‑8	NOUN
ctmj-188	217	12	cells	cell	NOUN
ctmj-188	217	13	.	.	PUNCT
ctmj-188	218	1	(	(	PUNCT
ctmj-188	218	2	c	c	NOUN
ctmj-188	218	3	and	and	CCONJ
ctmj-188	218	4	d	d	NOUN
ctmj-188	218	5	)	)	PUNCT
ctmj-188	218	6	dpd	dpd	PROPN
ctmj-188	218	7	and	and	CCONJ
ctmj-188	218	8	ts	ts	X
ctmj-188	218	9	in	in	ADP
ctmj-188	218	10	tumor	tumor	NOUN
ctmj-188	218	11	tissues	tissue	NOUN
ctmj-188	218	12	.	.	PUNCT
ctmj-188	219	1	*	*	PUNCT
ctmj-188	219	2	p	p	X
ctmj-188	219	3	<	<	X
ctmj-188	219	4	0.05	0.05	NUM
ctmj-188	219	5	compared	compare	VERB
ctmj-188	219	6	with	with	ADP
ctmj-188	219	7	the	the	DET
ctmj-188	219	8	control	control	NOUN
ctmj-188	219	9	group	group	NOUN
ctmj-188	219	10	;	;	PUNCT
ctmj-188	219	11	^	^	PUNCT
ctmj-188	219	12	p	p	X
ctmj-188	219	13	<	<	X
ctmj-188	219	14	0.05	0.05	NUM
ctmj-188	219	15	compared	compare	VERB
ctmj-188	219	16	with	with	ADP
ctmj-188	219	17	the	the	DET
ctmj-188	219	18	qfg	qfg	NOUN
ctmj-188	219	19	group	group	NOUN
ctmj-188	219	20	;	;	PUNCT
ctmj-188	219	21	#	#	SYM
ctmj-188	219	22	p	p	X
ctmj-188	219	23	<	<	X
ctmj-188	219	24	0.05	0.05	NUM
ctmj-188	219	25	compared	compare	VERB
ctmj-188	219	26	with	with	ADP
ctmj-188	219	27	the	the	DET
ctmj-188	219	28	5‑fu	5‑fu	PROPN
ctmj-188	219	29	group	group	NOUN
ctmj-188	219	30	.	.	PUNCT
ctmj-188	220	1	qfg	qfg	PROPN
ctmj-188	220	2	:	:	PUNCT
ctmj-188	220	3	qingjie	qingjie	PROPN
ctmj-188	220	4	fuzheng	fuzheng	PROPN
ctmj-188	220	5	granule	granule	PROPN
ctmj-188	220	6	,	,	PUNCT
ctmj-188	220	7	5‑fu	5‑fu	NUM
ctmj-188	220	8	:	:	PUNCT
ctmj-188	220	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	220	10	are	be	AUX
ctmj-188	220	11	repressed	repress	VERB
ctmj-188	220	12	by	by	ADP
ctmj-188	220	13	transcription	transcription	NOUN
ctmj-188	220	14	factors	factor	NOUN
ctmj-188	220	15	while	while	SCONJ
ctmj-188	220	16	mesenchymal	mesenchymal	ADJ
ctmj-188	220	17	genes	gene	NOUN
ctmj-188	220	18	are	be	AUX
ctmj-188	220	19	activated	activate	VERB
ctmj-188	220	20	,	,	PUNCT
ctmj-188	220	21	upregulate	upregulate	VERB
ctmj-188	220	22	vimentin	vimentin	NOUN
ctmj-188	220	23	(	(	PUNCT
ctmj-188	220	24	a	a	DET
ctmj-188	220	25	waveform	waveform	NOUN
ctmj-188	220	26	protein	protein	NOUN
ctmj-188	220	27	)	)	PUNCT
ctmj-188	220	28	expression	expression	NOUN
ctmj-188	220	29	,	,	PUNCT
ctmj-188	220	30	increase	increase	VERB
ctmj-188	220	31	extracellular	extracellular	ADJ
ctmj-188	220	32	deposition	deposition	NOUN
ctmj-188	220	33	of	of	ADP
ctmj-188	220	34	fibronectin	fibronectin	NOUN
ctmj-188	220	35	,	,	PUNCT
ctmj-188	220	36	thereby	thereby	ADV
ctmj-188	220	37	facilitating	facilitate	VERB
ctmj-188	220	38	metastasis.[35	metastasis.[35	PROPN
ctmj-188	220	39	-	-	PUNCT
ctmj-188	220	40	37	37	NUM
ctmj-188	220	41	]	]	PUNCT
ctmj-188	220	42	in	in	ADP
ctmj-188	220	43	this	this	DET
ctmj-188	220	44	study	study	NOUN
ctmj-188	220	45	,	,	PUNCT
ctmj-188	220	46	migration	migration	NOUN
ctmj-188	220	47	and	and	CCONJ
ctmj-188	220	48	invasion	invasion	NOUN
ctmj-188	220	49	assays	assay	NOUN
ctmj-188	220	50	revealed	reveal	VERB
ctmj-188	220	51	that	that	SCONJ
ctmj-188	220	52	qfg	qfg	NOUN
ctmj-188	220	53	combined	combine	VERB
ctmj-188	220	54	with	with	ADP
ctmj-188	220	55	5‑fu	5‑fu	PROPN
ctmj-188	220	56	significantly	significantly	ADV
ctmj-188	220	57	reduced	reduce	VERB
ctmj-188	220	58	the	the	DET
ctmj-188	220	59	migrated	migrate	VERB
ctmj-188	220	60	and	and	CCONJ
ctmj-188	220	61	invased	invase	VERB
ctmj-188	220	62	ability	ability	NOUN
ctmj-188	220	63	of	of	ADP
ctmj-188	220	64	crc	crc	NOUN
ctmj-188	220	65	cells	cell	NOUN
ctmj-188	220	66	.	.	PUNCT
ctmj-188	221	1	in‑depth	in‑depth	PROPN
ctmj-188	221	2	study	study	NOUN
ctmj-188	221	3	,	,	PUNCT
ctmj-188	221	4	treatment	treatment	NOUN
ctmj-188	221	5	with	with	ADP
ctmj-188	221	6	qfg	qfg	NOUN
ctmj-188	221	7	and	and	CCONJ
ctmj-188	221	8	5‑fu	5‑fu	PROPN
ctmj-188	221	9	affected	affect	VERB
ctmj-188	221	10	the	the	DET
ctmj-188	221	11	expression	expression	NOUN
ctmj-188	221	12	of	of	ADP
ctmj-188	221	13	emt‑related	emt‑relate	VERB
ctmj-188	221	14	factor	factor	NOUN
ctmj-188	221	15	,	,	PUNCT
ctmj-188	221	16	inhibited	inhibit	VERB
ctmj-188	221	17	emt	emt	NOUN
ctmj-188	221	18	occurrence	occurrence	NOUN
ctmj-188	221	19	,	,	PUNCT
ctmj-188	221	20	and	and	CCONJ
ctmj-188	221	21	synergistically	synergistically	ADV
ctmj-188	221	22	suppressed	suppress	VERB
ctmj-188	221	23	tumor	tumor	NOUN
ctmj-188	221	24	cell	cell	NOUN
ctmj-188	221	25	metastasis	metastasis	NOUN
ctmj-188	221	26	.	.	PUNCT
ctmj-188	222	1	5	5	NUM
ctmj-188	222	2	-	-	PUNCT
ctmj-188	222	3	fu	fu	NOUN
ctmj-188	222	4	blocks	block	VERB
ctmj-188	222	5	the	the	DET
ctmj-188	222	6	production	production	NOUN
ctmj-188	222	7	of	of	ADP
ctmj-188	222	8	dna	dna	PROPN
ctmj-188	222	9	in	in	ADP
ctmj-188	222	10	cells	cell	NOUN
ctmj-188	222	11	,	,	PUNCT
ctmj-188	222	12	which	which	PRON
ctmj-188	222	13	is	be	AUX
ctmj-188	222	14	how	how	SCONJ
ctmj-188	222	15	it	it	PRON
ctmj-188	222	16	fights	fight	VERB
ctmj-188	222	17	tumors	tumor	NOUN
ctmj-188	222	18	.	.	PUNCT
ctmj-188	223	1	because	because	SCONJ
ctmj-188	223	2	it	it	PRON
ctmj-188	223	3	facilitates	facilitate	VERB
ctmj-188	223	4	the	the	DET
ctmj-188	223	5	conversion	conversion	NOUN
ctmj-188	223	6	of	of	ADP
ctmj-188	223	7	dump	dump	NOUN
ctmj-188	223	8	to	to	AUX
ctmj-188	223	9	dtmp	dtmp	PROPN
ctmj-188	223	10	,	,	PUNCT
ctmj-188	223	11	the	the	DET
ctmj-188	223	12	only	only	ADJ
ctmj-188	223	13	thymidine	thymidine	ADJ
ctmj-188	223	14	nucleotide	nucleotide	NOUN
ctmj-188	223	15	required	require	VERB
ctmj-188	223	16	for	for	ADP
ctmj-188	223	17	dna	dna	ADJ
ctmj-188	223	18	synthesis	synthesis	NOUN
ctmj-188	223	19	and	and	CCONJ
ctmj-188	223	20	repair	repair	NOUN
ctmj-188	223	21	,	,	PUNCT
ctmj-188	223	22	ts	ts	X
ctmj-188	223	23	is	be	AUX
ctmj-188	223	24	also	also	ADV
ctmj-188	223	25	recognized	recognize	VERB
ctmj-188	223	26	as	as	ADP
ctmj-188	223	27	the	the	DET
ctmj-188	223	28	5	5	NUM
ctmj-188	223	29	-	-	PUNCT
ctmj-188	223	30	fu	fu	NOUN
ctmj-188	223	31	target	target	NOUN
ctmj-188	223	32	enzyme	enzyme	NOUN
ctmj-188	223	33	.	.	PUNCT
ctmj-188	224	1	downregulation	downregulation	NOUN
ctmj-188	224	2	of	of	ADP
ctmj-188	224	3	dpd	dpd	PROPN
ctmj-188	224	4	promotes	promote	VERB
ctmj-188	224	5	5	5	NUM
ctmj-188	224	6	-	-	PUNCT
ctmj-188	224	7	fu	fu	NOUN
ctmj-188	224	8	chemosensitivity	chemosensitivity	NOUN
ctmj-188	224	9	,	,	PUNCT
ctmj-188	224	10	and	and	CCONJ
ctmj-188	224	11	dpd	dpd	PROPN
ctmj-188	224	12	is	be	AUX
ctmj-188	224	13	a	a	DET
ctmj-188	224	14	rate	rate	NOUN
ctmj-188	224	15	-	-	PUNCT
ctmj-188	224	16	limiting	limit	VERB
ctmj-188	224	17	enzyme	enzyme	NOUN
ctmj-188	224	18	in	in	ADP
ctmj-188	224	19	5	5	NUM
ctmj-188	224	20	-	-	PUNCT
ctmj-188	224	21	fu	fu	NOUN
ctmj-188	224	22	degradation	degradation	NOUN
ctmj-188	224	23	.	.	PUNCT
ctmj-188	225	1	sections	section	NOUN
ctmj-188	225	2	38–40	38–40	NUM
ctmj-188	226	1	this	this	DET
ctmj-188	226	2	research	research	NOUN
ctmj-188	226	3	found	find	VERB
ctmj-188	226	4	that	that	SCONJ
ctmj-188	226	5	the	the	DET
ctmj-188	226	6	combination	combination	NOUN
ctmj-188	226	7	of	of	ADP
ctmj-188	226	8	qfg	qfg	NOUN
ctmj-188	226	9	and	and	CCONJ
ctmj-188	226	10	5	5	NUM
ctmj-188	226	11	-	-	PUNCT
ctmj-188	226	12	fu	fu	NOUN
ctmj-188	226	13	substantially	substantially	ADV
ctmj-188	226	14	reduced	reduce	VERB
ctmj-188	226	15	dpd	dpd	NOUN
ctmj-188	226	16	and	and	CCONJ
ctmj-188	226	17	ts	ts	ADP
ctmj-188	226	18	expression	expression	NOUN
ctmj-188	226	19	compared	compare	VERB
ctmj-188	226	20	to	to	ADP
ctmj-188	226	21	the	the	DET
ctmj-188	226	22	single	single	ADJ
ctmj-188	226	23	-	-	PUNCT
ctmj-188	226	24	drug	drug	NOUN
ctmj-188	226	25	therapy	therapy	NOUN
ctmj-188	226	26	.	.	PUNCT
ctmj-188	227	1	this	this	PRON
ctmj-188	227	2	suggests	suggest	VERB
ctmj-188	227	3	that	that	SCONJ
ctmj-188	227	4	the	the	DET
ctmj-188	227	5	combination	combination	NOUN
ctmj-188	227	6	of	of	ADP
ctmj-188	227	7	the	the	DET
ctmj-188	227	8	two	two	NUM
ctmj-188	227	9	drugs	drug	NOUN
ctmj-188	227	10	may	may	AUX
ctmj-188	227	11	enhance	enhance	VERB
ctmj-188	227	12	the	the	DET
ctmj-188	227	13	effectiveness	effectiveness	NOUN
ctmj-188	227	14	of	of	ADP
ctmj-188	227	15	5	5	NUM
ctmj-188	227	16	-	-	PUNCT
ctmj-188	227	17	fu	fu	NOUN
ctmj-188	227	18	by	by	ADP
ctmj-188	227	19	inhibiting	inhibit	VERB
ctmj-188	227	20	5	5	NUM
ctmj-188	227	21	-	-	PUNCT
ctmj-188	227	22	fu	fu	NOUN
ctmj-188	227	23	-	-	PUNCT
ctmj-188	227	24	related	relate	VERB
ctmj-188	227	25	negative	negative	ADJ
ctmj-188	227	26	regulatory	regulatory	ADJ
ctmj-188	227	27	enzymes	enzyme	NOUN
ctmj-188	227	28	.	.	PUNCT
ctmj-188	228	1	tumor	tumor	NOUN
ctmj-188	228	2	growth	growth	NOUN
ctmj-188	228	3	may	may	AUX
ctmj-188	228	4	be	be	AUX
ctmj-188	228	5	accelerated	accelerate	VERB
ctmj-188	228	6	by	by	ADP
ctmj-188	228	7	the	the	DET
ctmj-188	228	8	pi3k	pi3k	PROPN
ctmj-188	228	9	/	/	SYM
ctmj-188	228	10	akt	akt	PROPN
ctmj-188	228	11	signaling	signal	VERB
ctmj-188	228	12	pathway	pathway	NOUN
ctmj-188	228	13	.	.	PUNCT
ctmj-188	229	1	in	in	ADP
ctmj-188	229	2	order	order	NOUN
ctmj-188	229	3	to	to	PART
ctmj-188	229	4	partially	partially	ADV
ctmj-188	229	5	activate	activate	VERB
ctmj-188	229	6	akt	akt	PROPN
ctmj-188	229	7	and	and	CCONJ
ctmj-188	229	8	then	then	ADV
ctmj-188	229	9	modulate	modulate	VERB
ctmj-188	229	10	its	its	PRON
ctmj-188	229	11	activity	activity	NOUN
ctmj-188	229	12	,	,	PUNCT
ctmj-188	229	13	pi3k	pi3k	NOUN
ctmj-188	229	14	activation	activation	NOUN
ctmj-188	229	15	may	may	AUX
ctmj-188	229	16	produce	produce	VERB
ctmj-188	229	17	pip3	pip3	NOUN
ctmj-188	229	18	,	,	PUNCT
ctmj-188	229	19	which	which	PRON
ctmj-188	229	20	acts	act	VERB
ctmj-188	229	21	as	as	ADP
ctmj-188	229	22	a	a	DET
ctmj-188	229	23	second	second	ADJ
ctmj-188	229	24	messenger	messenger	NOUN
ctmj-188	229	25	to	to	PART
ctmj-188	229	26	bring	bring	VERB
ctmj-188	229	27	pdk1	pdk1	NOUN
ctmj-188	229	28	and	and	CCONJ
ctmj-188	229	29	akt	akt	PROPN
ctmj-188	229	30	proteins	protein	NOUN
ctmj-188	229	31	to	to	ADP
ctmj-188	229	32	the	the	DET
ctmj-188	229	33	plasma	plasma	NOUN
ctmj-188	229	34	membrane	membrane	NOUN
ctmj-188	229	35	.	.	PUNCT
ctmj-188	230	1	route	route	NOUN
ctmj-188	230	2	that	that	PRON
ctmj-188	230	3	goes	go	VERB
ctmj-188	230	4	downstream	downstream	ADJ
ctmj-188	230	5	.	.	PUNCT
ctmj-188	231	1	tables	table	NOUN
ctmj-188	231	2	41–43	41–43	PROPN
ctmj-188	231	3	akt	akt	PROPN
ctmj-188	231	4	produces	produce	VERB
ctmj-188	231	5	several	several	ADJ
ctmj-188	231	6	outcomes	outcome	NOUN
ctmj-188	231	7	:	:	PUNCT
ctmj-188	231	8	1	1	X
ctmj-188	231	9	)	)	PUNCT
ctmj-188	231	10	the	the	DET
ctmj-188	231	11	phosphorylation	phosphorylation	NOUN
ctmj-188	231	12	of	of	ADP
ctmj-188	231	13	akt	akt	PROPN
ctmj-188	231	14	hinders	hinder	VERB
ctmj-188	231	15	cell	cell	NOUN
ctmj-188	231	16	proliferation	proliferation	NOUN
ctmj-188	231	17	by	by	ADP
ctmj-188	231	18	affecting	affect	VERB
ctmj-188	231	19	factors	factor	NOUN
ctmj-188	231	20	like	like	ADP
ctmj-188	231	21	p21	p21	NOUN
ctmj-188	231	22	;	;	PUNCT
ctmj-188	231	23	2	2	X
ctmj-188	231	24	)	)	PUNCT
ctmj-188	231	25	the	the	DET
ctmj-188	231	26	phosphorylation	phosphorylation	NOUN
ctmj-188	231	27	of	of	ADP
ctmj-188	231	28	akt	akt	PROPN
ctmj-188	231	29	affects	affect	VERB
ctmj-188	231	30	apoptosis	apoptosis	NOUN
ctmj-188	231	31	by	by	ADP
ctmj-188	231	32	preventing	prevent	VERB
ctmj-188	231	33	the	the	DET
ctmj-188	231	34	activity	activity	NOUN
ctmj-188	231	35	of	of	ADP
ctmj-188	231	36	bad	bad	ADJ
ctmj-188	231	37	(	(	PUNCT
ctmj-188	231	38	bcl-2	bcl-2	VERB
ctmj-188	231	39	-	-	ADJ
ctmj-188	231	40	associated	associate	VERB
ctmj-188	231	41	cell	cell	NOUN
ctmj-188	231	42	death	death	NOUN
ctmj-188	231	43	agonist	agonist	NOUN
ctmj-188	231	44	)	)	PUNCT
ctmj-188	231	45	;	;	PUNCT
ctmj-188	231	46	3	3	X
ctmj-188	231	47	)	)	PUNCT
ctmj-188	231	48	the	the	DET
ctmj-188	231	49	phosphorylation	phosphorylation	NOUN
ctmj-188	231	50	of	of	ADP
ctmj-188	231	51	akt	akt	PROPN
ctmj-188	231	52	positively	positively	ADV
ctmj-188	231	53	controls	control	VERB
ctmj-188	231	54	the	the	DET
ctmj-188	231	55	nf-b	nf-b	PROPN
ctmj-188	231	56	pathway	pathway	NOUN
ctmj-188	231	57	,	,	PUNCT
ctmj-188	231	58	which	which	PRON
ctmj-188	231	59	regulates	regulate	VERB
ctmj-188	231	60	emt	emt	NOUN
ctmj-188	231	61	and	and	CCONJ
ctmj-188	231	62	impacts	impact	NOUN
ctmj-188	231	63	cell	cell	NOUN
ctmj-188	231	64	metastasis	metastasis	NOUN
ctmj-188	231	65	.	.	PUNCT
ctmj-188	232	1	positions	position	NOUN
ctmj-188	232	2	11	11	NUM
ctmj-188	232	3	,	,	PUNCT
ctmj-188	232	4	44	44	NUM
ctmj-188	232	5	,	,	PUNCT
ctmj-188	232	6	and	and	CCONJ
ctmj-188	232	7	45	45	NUM
ctmj-188	232	8	treatment	treatment	NOUN
ctmj-188	232	9	with	with	ADP
ctmj-188	232	10	qfg	qfg	NOUN
ctmj-188	232	11	and	and	CCONJ
ctmj-188	232	12	5	5	NUM
ctmj-188	232	13	-	-	PUNCT
ctmj-188	232	14	fu	fu	NOUN
ctmj-188	232	15	,	,	PUNCT
ctmj-188	232	16	as	as	SCONJ
ctmj-188	232	17	revealed	reveal	VERB
ctmj-188	232	18	by	by	ADP
ctmj-188	232	19	the	the	DET
ctmj-188	232	20	results	result	NOUN
ctmj-188	232	21	of	of	ADP
ctmj-188	232	22	the	the	DET
ctmj-188	232	23	western	western	ADJ
ctmj-188	232	24	blot	blot	NOUN
ctmj-188	232	25	experiment	experiment	NOUN
ctmj-188	232	26	,	,	PUNCT
ctmj-188	232	27	disrupted	disrupt	VERB
ctmj-188	232	28	the	the	DET
ctmj-188	232	29	pi3k	pi3k	PROPN
ctmj-188	232	30	/	/	SYM
ctmj-188	232	31	akt	akt	PROPN
ctmj-188	232	32	signaling	signal	VERB
ctmj-188	232	33	pathway	pathway	NOUN
ctmj-188	232	34	,	,	PUNCT
ctmj-188	232	35	according	accord	VERB
ctmj-188	232	36	to	to	ADP
ctmj-188	232	37	this	this	DET
ctmj-188	232	38	research	research	NOUN
ctmj-188	232	39	.	.	PUNCT
ctmj-188	233	1	in	in	ADP
ctmj-188	233	2	this	this	DET
ctmj-188	233	3	work	work	NOUN
ctmj-188	233	4	,	,	PUNCT
ctmj-188	233	5	the	the	DET
ctmj-188	233	6	pi3k	pi3k	PROPN
ctmj-188	233	7	/	/	SYM
ctmj-188	233	8	akt	akt	PROPN
ctmj-188	233	9	signaling	signal	VERB
ctmj-188	233	10	pathway	pathway	NOUN
ctmj-188	233	11	was	be	AUX
ctmj-188	233	12	stimulated	stimulate	VERB
ctmj-188	233	13	by	by	ADP
ctmj-188	233	14	10	10	NUM
ctmj-188	233	15	%	%	NOUN
ctmj-188	233	16	fbs	fbs	PROPN
ctmj-188	233	17	,	,	PUNCT
ctmj-188	233	18	and	and	CCONJ
ctmj-188	233	19	the	the	DET
ctmj-188	233	20	effects	effect	NOUN
ctmj-188	233	21	of	of	ADP
ctmj-188	233	22	the	the	DET
ctmj-188	233	23	two	two	NUM
ctmj-188	233	24	medicines	medicine	NOUN
ctmj-188	233	25	coupled	couple	VERB
ctmj-188	233	26	with	with	ADP
ctmj-188	233	27	qfg	qfg	NOUN
ctmj-188	233	28	were	be	AUX
ctmj-188	233	29	investigated	investigate	VERB
ctmj-188	233	30	.	.	PUNCT
ctmj-188	234	1	10	10	NUM
ctmj-188	234	2	%	%	NOUN
ctmj-188	234	3	fbs	fbs	PROPN
ctmj-188	234	4	triggered	trigger	VERB
ctmj-188	234	5	the	the	DET
ctmj-188	234	6	akt	akt	NOUN
ctmj-188	234	7	signaling	signal	VERB
ctmj-188	234	8	pathway	pathway	NOUN
ctmj-188	234	9	.	.	PUNCT
ctmj-188	235	1	the	the	DET
ctmj-188	235	2	combined	combined	ADJ
ctmj-188	235	3	treatment	treatment	NOUN
ctmj-188	235	4	of	of	ADP
ctmj-188	235	5	qfg	qfg	NOUN
ctmj-188	235	6	and	and	CCONJ
ctmj-188	235	7	5	5	NUM
ctmj-188	235	8	-	-	PUNCT
ctmj-188	235	9	fu	fu	NOUN
ctmj-188	235	10	controlled	control	VERB
ctmj-188	235	11	the	the	DET
ctmj-188	235	12	proliferation	proliferation	NOUN
ctmj-188	235	13	,	,	PUNCT
ctmj-188	235	14	apoptosis	apoptosis	NOUN
ctmj-188	235	15	,	,	PUNCT
ctmj-188	235	16	and	and	CCONJ
ctmj-188	235	17	metastasis	metastasis	NOUN
ctmj-188	235	18	of	of	ADP
ctmj-188	235	19	hct-8	hct-8	PUNCT
ctmj-188	235	20	cells	cell	NOUN
ctmj-188	235	21	,	,	PUNCT
ctmj-188	235	22	which	which	PRON
ctmj-188	235	23	were	be	AUX
ctmj-188	235	24	followed	follow	VERB
ctmj-188	235	25	by	by	ADP
ctmj-188	235	26	the	the	DET
ctmj-188	235	27	activation	activation	NOUN
ctmj-188	235	28	of	of	ADP
ctmj-188	235	29	pi3k	pi3k	PROPN
ctmj-188	235	30	and	and	CCONJ
ctmj-188	235	31	akt	akt	PROPN
ctmj-188	235	32	,	,	PUNCT
ctmj-188	235	33	according	accord	VERB
ctmj-188	235	34	to	to	ADP
ctmj-188	235	35	functional	functional	ADJ
ctmj-188	235	36	tests	test	NOUN
ctmj-188	235	37	.	.	PUNCT
ctmj-188	236	1	the	the	DET
ctmj-188	236	2	findings	finding	NOUN
ctmj-188	236	3	show	show	VERB
ctmj-188	236	4	that	that	SCONJ
ctmj-188	236	5	the	the	DET
ctmj-188	236	6	pi3k	pi3k	PROPN
ctmj-188	236	7	/	/	SYM
ctmj-188	236	8	akt	akt	PROPN
ctmj-188	236	9	signaling	signal	VERB
ctmj-188	236	10	system	system	NOUN
ctmj-188	236	11	's	's	PART
ctmj-188	236	12	downstream	downstream	ADJ
ctmj-188	236	13	pathway	pathway	NOUN
ctmj-188	236	14	may	may	AUX
ctmj-188	236	15	be	be	AUX
ctmj-188	236	16	regulated	regulate	VERB
ctmj-188	236	17	by	by	ADP
ctmj-188	236	18	combining	combine	VERB
ctmj-188	236	19	qfg	qfg	NOUN
ctmj-188	236	20	and	and	CCONJ
ctmj-188	236	21	5	5	NUM
ctmj-188	236	22	-	-	PUNCT
ctmj-188	236	23	fu	fu	NOUN
ctmj-188	236	24	therapy	therapy	NOUN
ctmj-188	236	25	,	,	PUNCT
ctmj-188	236	26	which	which	PRON
ctmj-188	236	27	in	in	ADP
ctmj-188	236	28	turn	turn	NOUN
ctmj-188	236	29	controls	control	VERB
ctmj-188	236	30	the	the	DET
ctmj-188	236	31	proliferation	proliferation	NOUN
ctmj-188	236	32	,	,	PUNCT
ctmj-188	236	33	apoptosis	apoptosis	NOUN
ctmj-188	236	34	,	,	PUNCT
ctmj-188	236	35	metastasis	metastasis	NOUN
ctmj-188	236	36	,	,	PUNCT
ctmj-188	236	37	and	and	CCONJ
ctmj-188	236	38	5	5	NUM
ctmj-188	236	39	-	-	PUNCT
ctmj-188	236	40	fu	fu	NOUN
ctmj-188	236	41	chemoresistance	chemoresistance	NOUN
ctmj-188	236	42	of	of	ADP
ctmj-188	236	43	crc	crc	PROPN
ctmj-188	236	44	.	.	PUNCT
ctmj-188	237	1	conclusions	conclusion	NOUN
ctmj-188	237	2	in	in	ADP
ctmj-188	237	3	summary	summary	NOUN
ctmj-188	237	4	,	,	PUNCT
ctmj-188	237	5	we	we	PRON
ctmj-188	237	6	demonstrated	demonstrate	VERB
ctmj-188	237	7	for	for	ADP
ctmj-188	237	8	the	the	DET
ctmj-188	237	9	first	first	ADJ
ctmj-188	237	10	time	time	NOUN
ctmj-188	237	11	that	that	SCONJ
ctmj-188	237	12	combined	combined	ADJ
ctmj-188	237	13	treatment	treatment	NOUN
ctmj-188	237	14	qfg	qfg	NOUN
ctmj-188	237	15	with	with	ADP
ctmj-188	237	16	5‑fu	5‑fu	PROPN
ctmj-188	237	17	has	have	VERB
ctmj-188	237	18	a	a	DET
ctmj-188	237	19	synergistic	synergistic	ADJ
ctmj-188	237	20	ability	ability	NOUN
ctmj-188	237	21	against	against	ADP
ctmj-188	237	22	crc	crc	NOUN
ctmj-188	237	23	,	,	PUNCT
ctmj-188	237	24	which	which	PRON
ctmj-188	237	25	inhibits	inhibit	VERB
ctmj-188	237	26	cell	cell	NOUN
ctmj-188	237	27	proliferation	proliferation	NOUN
ctmj-188	237	28	,	,	PUNCT
ctmj-188	237	29	metastasis	metastasis	NOUN
ctmj-188	237	30	,	,	PUNCT
ctmj-188	237	31	induces	induce	VERB
ctmj-188	237	32	apoptosis	apoptosis	NOUN
ctmj-188	237	33	.	.	PUNCT
ctmj-188	238	1	the	the	DET
ctmj-188	238	2	downstream	downstream	NOUN
ctmj-188	238	3	of	of	ADP
ctmj-188	238	4	pi3k/	pi3k/	NOUN
ctmj-188	238	5	a	a	DET
ctmj-188	238	6	b	b	NOUN
ctmj-188	238	7	c	c	NOUN
ctmj-188	238	8	d	d	SYM
ctmj-188	238	9	54	54	NUM
ctmj-188	238	10	ctmj	ctmj	NOUN
ctmj-188	238	11	|	|	ADV
ctmj-188	238	12	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	238	13	chinese	chinese	ADJ
ctmj-188	238	14	traditional	traditional	ADJ
ctmj-188	238	15	medicine	medicine	NOUN
ctmj-188	238	16	journal	journal	NOUN
ctmj-188	238	17	|	|	ADV
ctmj-188	238	18	2025	2025	NUM
ctmj-188	238	19	|	|	ADV
ctmj-188	238	20	vol	vol	NOUN
ctmj-188	238	21	8	8	NUM
ctmj-188	238	22	|issue	|issue	NOUN
ctmj-188	238	23	1	1	NUM
ctmj-188	238	24	54	54	NUM
ctmj-188	238	25	a	a	DET
ctmj-188	238	26	b	b	NOUN
ctmj-188	238	27	c	c	NOUN
ctmj-188	238	28	d	d	NOUN
ctmj-188	238	29	figure	figure	NOUN
ctmj-188	238	30	8	8	NUM
ctmj-188	238	31	:	:	PUNCT
ctmj-188	238	32	qingjie	qingjie	NOUN
ctmj-188	238	33	fuzheng	fuzheng	PROPN
ctmj-188	238	34	granule	granule	PROPN
ctmj-188	238	35	(	(	PUNCT
ctmj-188	238	36	qfg	qfg	NOUN
ctmj-188	238	37	)	)	PUNCT
ctmj-188	238	38	combined	combine	VERB
ctmj-188	238	39	with	with	ADP
ctmj-188	238	40	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	238	41	(	(	PUNCT
ctmj-188	238	42	5‑fu	5‑fu	PROPN
ctmj-188	238	43	)	)	PUNCT
ctmj-188	238	44	synergisticly	synergisticly	ADV
ctmj-188	238	45	inhibited	inhibit	VERB
ctmj-188	238	46	the	the	DET
ctmj-188	238	47	pi3k	pi3k	PROPN
ctmj-188	238	48	/	/	SYM
ctmj-188	238	49	akt	akt	PROPN
ctmj-188	238	50	signaling	signal	VERB
ctmj-188	238	51	pathway	pathway	NOUN
ctmj-188	238	52	.	.	PUNCT
ctmj-188	239	1	(	(	PUNCT
ctmj-188	239	2	a	a	PRON
ctmj-188	239	3	and	and	CCONJ
ctmj-188	239	4	b	b	NOUN
ctmj-188	239	5	)	)	PUNCT
ctmj-188	239	6	qfg	qfg	NOUN
ctmj-188	239	7	and	and	CCONJ
ctmj-188	239	8	5‑fu	5‑fu	NUM
ctmj-188	239	9	blocked	block	VERB
ctmj-188	239	10	phosphorylation	phosphorylation	NOUN
ctmj-188	239	11	of	of	ADP
ctmj-188	239	12	pi3k	pi3k	PROPN
ctmj-188	239	13	and	and	CCONJ
ctmj-188	239	14	akt	akt	VERB
ctmj-188	239	15	in	in	ADP
ctmj-188	239	16	hct‑8	hct‑8	NOUN
ctmj-188	239	17	cells	cell	NOUN
ctmj-188	239	18	.	.	PUNCT
ctmj-188	240	1	(	(	PUNCT
ctmj-188	240	2	c	c	NOUN
ctmj-188	240	3	and	and	CCONJ
ctmj-188	240	4	d	d	NOUN
ctmj-188	240	5	)	)	PUNCT
ctmj-188	240	6	qfg	qfg	NOUN
ctmj-188	240	7	and	and	CCONJ
ctmj-188	240	8	5‑fu	5‑fu	NUM
ctmj-188	240	9	blocked	block	VERB
ctmj-188	240	10	phosphorylation	phosphorylation	NOUN
ctmj-188	240	11	of	of	ADP
ctmj-188	240	12	pi3k	pi3k	PROPN
ctmj-188	240	13	and	and	CCONJ
ctmj-188	240	14	akt	akt	PROPN
ctmj-188	240	15	in	in	ADP
ctmj-188	240	16	tumor	tumor	NOUN
ctmj-188	240	17	tissues	tissue	NOUN
ctmj-188	240	18	.	.	PUNCT
ctmj-188	241	1	*	*	PUNCT
ctmj-188	241	2	p	p	X
ctmj-188	241	3	<	<	X
ctmj-188	241	4	0.05	0.05	NUM
ctmj-188	241	5	compared	compare	VERB
ctmj-188	241	6	to	to	ADP
ctmj-188	241	7	the	the	DET
ctmj-188	241	8	control	control	NOUN
ctmj-188	241	9	group	group	NOUN
ctmj-188	241	10	;	;	PUNCT
ctmj-188	241	11	^	^	PUNCT
ctmj-188	241	12	p	p	X
ctmj-188	241	13	<	<	X
ctmj-188	241	14	0.05	0.05	NUM
ctmj-188	241	15	compared	compare	VERB
ctmj-188	241	16	to	to	ADP
ctmj-188	241	17	the	the	DET
ctmj-188	241	18	qfg	qfg	ADJ
ctmj-188	241	19	group	group	NOUN
ctmj-188	241	20	;	;	PUNCT
ctmj-188	241	21	#	#	SYM
ctmj-188	241	22	p	p	X
ctmj-188	241	23	<	<	X
ctmj-188	241	24	0.05	0.05	NUM
ctmj-188	241	25	compared	compare	VERB
ctmj-188	241	26	to	to	ADP
ctmj-188	241	27	the	the	DET
ctmj-188	241	28	5‑fu	5‑fu	PROPN
ctmj-188	241	29	group	group	NOUN
ctmj-188	241	30	.	.	PUNCT
ctmj-188	242	1	qfg	qfg	PROPN
ctmj-188	242	2	:	:	PUNCT
ctmj-188	242	3	qingjie	qingjie	PROPN
ctmj-188	242	4	fuzheng	fuzheng	PROPN
ctmj-188	242	5	granule	granule	PROPN
ctmj-188	242	6	,	,	PUNCT
ctmj-188	242	7	5‑fu	5‑fu	NUM
ctmj-188	242	8	:	:	PUNCT
ctmj-188	242	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	242	10	figure	figure	NOUN
ctmj-188	242	11	9	9	NUM
ctmj-188	242	12	:	:	PUNCT
ctmj-188	242	13	effect	effect	NOUN
ctmj-188	242	14	of	of	ADP
ctmj-188	242	15	qingjie	qingjie	NOUN
ctmj-188	242	16	fuzheng	fuzheng	PROPN
ctmj-188	242	17	granule	granule	PROPN
ctmj-188	242	18	(	(	PUNCT
ctmj-188	242	19	qfg	qfg	ADJ
ctmj-188	242	20	)	)	PUNCT
ctmj-188	242	21	and	and	CCONJ
ctmj-188	242	22	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	242	23	(	(	PUNCT
ctmj-188	242	24	5‑fu	5‑fu	PROPN
ctmj-188	242	25	)	)	PUNCT
ctmj-188	242	26	on	on	ADP
ctmj-188	242	27	the	the	DET
ctmj-188	242	28	activation	activation	NOUN
ctmj-188	242	29	of	of	ADP
ctmj-188	242	30	the	the	DET
ctmj-188	242	31	pi3k	pi3k	PROPN
ctmj-188	242	32	/	/	SYM
ctmj-188	242	33	akt	akt	PROPN
ctmj-188	242	34	pathway	pathway	NOUN
ctmj-188	242	35	by	by	ADP
ctmj-188	242	36	10	10	NUM
ctmj-188	242	37	%	%	NOUN
ctmj-188	242	38	fbs	fbs	ADJ
ctmj-188	242	39	.	.	PUNCT
ctmj-188	243	1	(	(	PUNCT
ctmj-188	243	2	a	a	PRON
ctmj-188	243	3	and	and	CCONJ
ctmj-188	243	4	b	b	NOUN
ctmj-188	243	5	)	)	PUNCT
ctmj-188	243	6	fbs	fbs	PROPN
ctmj-188	243	7	induced	induce	VERB
ctmj-188	243	8	akt	akt	PROPN
ctmj-188	243	9	phosphonation	phosphonation	NOUN
ctmj-188	243	10	in	in	ADP
ctmj-188	243	11	different	different	ADJ
ctmj-188	243	12	time	time	NOUN
ctmj-188	243	13	.	.	PUNCT
ctmj-188	244	1	(	(	PUNCT
ctmj-188	244	2	c	c	NOUN
ctmj-188	244	3	and	and	CCONJ
ctmj-188	244	4	d	d	NOUN
ctmj-188	244	5	)	)	PUNCT
ctmj-188	244	6	qfg	qfg	NOUN
ctmj-188	244	7	and	and	CCONJ
ctmj-188	244	8	5‑fu	5‑fu	PROPN
ctmj-188	244	9	inhibited	inhibit	VERB
ctmj-188	244	10	the	the	DET
ctmj-188	244	11	akt	akt	PROPN
ctmj-188	244	12	phosphonation	phosphonation	NOUN
ctmj-188	244	13	.	.	PUNCT
ctmj-188	245	1	$	$	SYM
ctmj-188	245	2	p	p	X
ctmj-188	245	3	<	<	X
ctmj-188	245	4	0.05	0.05	NUM
ctmj-188	245	5	compared	compare	VERB
ctmj-188	245	6	with	with	ADP
ctmj-188	245	7	the	the	DET
ctmj-188	245	8	fbs	fbs	PROPN
ctmj-188	245	9	free	free	ADJ
ctmj-188	245	10	group	group	NOUN
ctmj-188	245	11	;	;	PUNCT
ctmj-188	245	12	*	*	PUNCT
ctmj-188	245	13	p	p	X
ctmj-188	245	14	<	<	X
ctmj-188	245	15	0.05	0.05	NUM
ctmj-188	245	16	compared	compare	VERB
ctmj-188	245	17	with	with	ADP
ctmj-188	245	18	the	the	DET
ctmj-188	245	19	fbs	fbs	PROPN
ctmj-188	245	20	group	group	NOUN
ctmj-188	245	21	.	.	PUNCT
ctmj-188	246	1	qfg	qfg	PROPN
ctmj-188	246	2	:	:	PUNCT
ctmj-188	246	3	qingjie	qingjie	PROPN
ctmj-188	246	4	fuzheng	fuzheng	PROPN
ctmj-188	246	5	granule	granule	PROPN
ctmj-188	246	6	,	,	PUNCT
ctmj-188	246	7	5‑fu	5‑fu	NUM
ctmj-188	246	8	:	:	PUNCT
ctmj-188	246	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	246	10	a	a	DET
ctmj-188	246	11	b	b	NOUN
ctmj-188	246	12	c	c	NOUN
ctmj-188	246	13	d	d	SYM
ctmj-188	246	14	55	55	NUM
ctmj-188	246	15	ctmj	ctmj	NOUN
ctmj-188	247	1	|	|	ADV
ctmj-188	247	2	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	247	3	chinese	chinese	ADJ
ctmj-188	247	4	traditional	traditional	ADJ
ctmj-188	247	5	medicine	medicine	NOUN
ctmj-188	247	6	journal	journal	NOUN
ctmj-188	247	7	|	|	ADV
ctmj-188	247	8	2025	2025	NUM
ctmj-188	247	9	|	|	ADV
ctmj-188	247	10	vol	vol	NOUN
ctmj-188	247	11	8	8	NUM
ctmj-188	247	12	|issue	|issue	NOUN
ctmj-188	247	13	1	1	NUM
ctmj-188	247	14	55	55	NUM
ctmj-188	247	15	c	c	NOUN
ctmj-188	247	16	e	e	X
ctmj-188	247	17	a	a	PRON
ctmj-188	247	18	b	b	NOUN
ctmj-188	247	19	d	d	NOUN
ctmj-188	247	20	g	g	PROPN
ctmj-188	247	21	f	f	PROPN
ctmj-188	247	22	h	h	NOUN
ctmj-188	248	1	i	i	PRON
ctmj-188	248	2	figure	figure	VERB
ctmj-188	248	3	10	10	NUM
ctmj-188	248	4	:	:	PUNCT
ctmj-188	248	5	qingjie	qingjie	PROPN
ctmj-188	248	6	fuzheng	fuzheng	PROPN
ctmj-188	248	7	granule	granule	PROPN
ctmj-188	248	8	(	(	PUNCT
ctmj-188	248	9	qfg	qfg	NOUN
ctmj-188	248	10	)	)	PUNCT
ctmj-188	248	11	combined	combine	VERB
ctmj-188	248	12	with	with	ADP
ctmj-188	248	13	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	248	14	(	(	PUNCT
ctmj-188	248	15	5‑fu	5‑fu	NOUN
ctmj-188	248	16	)	)	PUNCT
ctmj-188	248	17	regulated	regulated	ADJ
ctmj-188	248	18	proliferation	proliferation	NOUN
ctmj-188	248	19	,	,	PUNCT
ctmj-188	248	20	apoptosis	apoptosis	NOUN
ctmj-188	248	21	,	,	PUNCT
ctmj-188	248	22	migration	migration	NOUN
ctmj-188	248	23	and	and	CCONJ
ctmj-188	248	24	invasion	invasion	NOUN
ctmj-188	248	25	via	via	ADP
ctmj-188	248	26	inhibiting	inhibit	VERB
ctmj-188	248	27	pi3k	pi3k	PROPN
ctmj-188	248	28	/	/	SYM
ctmj-188	248	29	akt	akt	PROPN
ctmj-188	248	30	pathway	pathway	NOUN
ctmj-188	248	31	.	.	PUNCT
ctmj-188	249	1	(	(	PUNCT
ctmj-188	249	2	a	a	X
ctmj-188	249	3	)	)	PUNCT
ctmj-188	249	4	morphology	morphology	NOUN
ctmj-188	249	5	.	.	PUNCT
ctmj-188	250	1	(	(	PUNCT
ctmj-188	250	2	b	b	NOUN
ctmj-188	250	3	and	and	CCONJ
ctmj-188	250	4	c	c	NOUN
ctmj-188	250	5	)	)	PUNCT
ctmj-188	250	6	colony	colony	NOUN
ctmj-188	250	7	formation	formation	NOUN
ctmj-188	250	8	and	and	CCONJ
ctmj-188	250	9	statistical	statistical	ADJ
ctmj-188	250	10	analysis	analysis	NOUN
ctmj-188	250	11	;	;	PUNCT
ctmj-188	250	12	(	(	PUNCT
ctmj-188	250	13	d	d	NOUN
ctmj-188	250	14	and	and	CCONJ
ctmj-188	250	15	e	e	NOUN
ctmj-188	250	16	)	)	PUNCT
ctmj-188	250	17	dapi	dapi	ADJ
ctmj-188	250	18	staining	staining	ADJ
ctmj-188	250	19	and	and	CCONJ
ctmj-188	250	20	statistical	statistical	ADJ
ctmj-188	250	21	analysis	analysis	NOUN
ctmj-188	250	22	(	(	PUNCT
ctmj-188	250	23	×200	×200	PROPN
ctmj-188	250	24	,	,	PUNCT
ctmj-188	250	25	ba	ba	PROPN
ctmj-188	250	26	r	r	NOUN
ctmj-188	250	27	=	=	SYM
ctmj-188	250	28	100	100	NUM
ctmj-188	250	29	m	m	NOUN
ctmj-188	250	30	)	)	PUNCT
ctmj-188	250	31	.	.	PUNCT
ctmj-188	251	1	(	(	PUNCT
ctmj-188	251	2	f	f	NOUN
ctmj-188	251	3	and	and	CCONJ
ctmj-188	251	4	g	g	NOUN
ctmj-188	251	5	)	)	PUNCT
ctmj-188	251	6	migration	migration	NOUN
ctmj-188	251	7	and	and	CCONJ
ctmj-188	251	8	statistical	statistical	ADJ
ctmj-188	251	9	analysis	analysis	NOUN
ctmj-188	251	10	(	(	PUNCT
ctmj-188	251	11	×200	×200	PROPN
ctmj-188	251	12	,	,	PUNCT
ctmj-188	251	13	bar	bar	NOUN
ctmj-188	251	14	=	=	SYM
ctmj-188	251	15	100	100	NUM
ctmj-188	251	16	m	m	PROPN
ctmj-188	251	17	)	)	PUNCT
ctmj-188	251	18	;	;	PUNCT
ctmj-188	251	19	(	(	PUNCT
ctmj-188	251	20	h	h	NOUN
ctmj-188	251	21	and	and	CCONJ
ctmj-188	251	22	i	i	NOUN
ctmj-188	251	23	)	)	PUNCT
ctmj-188	251	24	invasion	invasion	NOUN
ctmj-188	251	25	and	and	CCONJ
ctmj-188	251	26	statistical	statistical	ADJ
ctmj-188	251	27	analysis	analysis	NOUN
ctmj-188	251	28	(	(	PUNCT
ctmj-188	251	29	×200	×200	PROPN
ctmj-188	251	30	,	,	PUNCT
ctmj-188	251	31	bar	bar	NOUN
ctmj-188	251	32	=	=	PUNCT
ctmj-188	251	33	100	100	NUM
ctmj-188	251	34	m	m	NOUN
ctmj-188	251	35	)	)	PUNCT
ctmj-188	251	36	.	.	PUNCT
ctmj-188	252	1	$	$	SYM
ctmj-188	252	2	p	p	X
ctmj-188	252	3	<	<	X
ctmj-188	252	4	0.05	0.05	NUM
ctmj-188	252	5	compared	compare	VERB
ctmj-188	252	6	with	with	ADP
ctmj-188	252	7	the	the	DET
ctmj-188	252	8	fbs‑free	fbs‑free	PROPN
ctmj-188	252	9	group	group	NOUN
ctmj-188	252	10	;	;	PUNCT
ctmj-188	252	11	*	*	PUNCT
ctmj-188	252	12	p	p	X
ctmj-188	252	13	<	<	X
ctmj-188	252	14	0.05	0.05	NUM
ctmj-188	252	15	compared	compare	VERB
ctmj-188	252	16	with	with	ADP
ctmj-188	252	17	the	the	DET
ctmj-188	252	18	fbs	fbs	PROPN
ctmj-188	252	19	group	group	NOUN
ctmj-188	252	20	;	;	PUNCT
ctmj-188	252	21	^	^	PUNCT
ctmj-188	252	22	p	p	X
ctmj-188	252	23	<	<	X
ctmj-188	252	24	0.05	0.05	NUM
ctmj-188	252	25	compared	compare	VERB
ctmj-188	252	26	with	with	ADP
ctmj-188	252	27	the	the	DET
ctmj-188	252	28	fbs	fbs	PROPN
ctmj-188	252	29	+	+	CCONJ
ctmj-188	252	30	qfg	qfg	ADJ
ctmj-188	252	31	group	group	NOUN
ctmj-188	252	32	;	;	PUNCT
ctmj-188	252	33	#	#	SYM
ctmj-188	252	34	p	p	X
ctmj-188	252	35	<	<	X
ctmj-188	252	36	0.05	0.05	NUM
ctmj-188	252	37	compared	compare	VERB
ctmj-188	252	38	with	with	ADP
ctmj-188	252	39	the	the	DET
ctmj-188	252	40	fbs	fbs	PROPN
ctmj-188	252	41	+	+	CCONJ
ctmj-188	252	42	5‑fu	5‑fu	PROPN
ctmj-188	252	43	group	group	NOUN
ctmj-188	252	44	.	.	PUNCT
ctmj-188	253	1	qfg	qfg	PROPN
ctmj-188	253	2	:	:	PUNCT
ctmj-188	253	3	qingjie	qingjie	PROPN
ctmj-188	253	4	fuzheng	fuzheng	PROPN
ctmj-188	253	5	granule	granule	PROPN
ctmj-188	253	6	,	,	PUNCT
ctmj-188	253	7	5‑fu	5‑fu	NUM
ctmj-188	253	8	:	:	PUNCT
ctmj-188	253	9	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	253	10	akt	akt	NOUN
ctmj-188	253	11	signaling	signal	VERB
ctmj-188	253	12	pathway	pathway	NOUN
ctmj-188	253	13	involves	involve	VERB
ctmj-188	253	14	tumor	tumor	NOUN
ctmj-188	253	15	proliferation	proliferation	NOUN
ctmj-188	253	16	,	,	PUNCT
ctmj-188	253	17	56	56	NUM
ctmj-188	253	18	ctmj	ctmj	NOUN
ctmj-188	253	19	|	|	ADV
ctmj-188	253	20	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	253	21	chinese	chinese	ADJ
ctmj-188	253	22	traditional	traditional	ADJ
ctmj-188	253	23	medicine	medicine	NOUN
ctmj-188	253	24	journal	journal	NOUN
ctmj-188	253	25	|	|	ADV
ctmj-188	253	26	2025	2025	NUM
ctmj-188	253	27	|	|	ADV
ctmj-188	253	28	vol	vol	NOUN
ctmj-188	253	29	8	8	NUM
ctmj-188	253	30	|issue	|issue	NOUN
ctmj-188	253	31	1	1	NUM
ctmj-188	253	32	56	56	NUM
ctmj-188	253	33	apoptosis	apoptosis	NOUN
ctmj-188	253	34	,	,	PUNCT
ctmj-188	253	35	metastasis	metastasis	NOUN
ctmj-188	253	36	and	and	CCONJ
ctmj-188	253	37	other	other	ADJ
ctmj-188	253	38	related	related	ADJ
ctmj-188	253	39	processes	process	NOUN
ctmj-188	253	40	.	.	PUNCT
ctmj-188	254	1	our	our	PRON
ctmj-188	254	2	results	result	NOUN
ctmj-188	254	3	demonstrate	demonstrate	VERB
ctmj-188	254	4	that	that	SCONJ
ctmj-188	254	5	the	the	DET
ctmj-188	254	6	combined	combined	ADJ
ctmj-188	254	7	treatment	treatment	NOUN
ctmj-188	254	8	of	of	ADP
ctmj-188	254	9	qfg	qfg	NOUN
ctmj-188	254	10	with	with	ADP
ctmj-188	254	11	and	and	CCONJ
ctmj-188	254	12	5‑fu	5‑fu	PROPN
ctmj-188	254	13	exerts	exert	VERB
ctmj-188	254	14	its	its	PRON
ctmj-188	254	15	inhibitory	inhibitory	ADJ
ctmj-188	254	16	capability	capability	NOUN
ctmj-188	254	17	on	on	ADP
ctmj-188	254	18	crc	crc	NOUN
ctmj-188	254	19	cells	cell	NOUN
ctmj-188	254	20	though	though	SCONJ
ctmj-188	254	21	regulating	regulate	VERB
ctmj-188	254	22	pi3k	pi3k	PROPN
ctmj-188	254	23	/	/	SYM
ctmj-188	254	24	akt	akt	PROPN
ctmj-188	254	25	signaling	signal	VERB
ctmj-188	254	26	pathway	pathway	NOUN
ctmj-188	254	27	.	.	PUNCT
ctmj-188	255	1	this	this	DET
ctmj-188	255	2	regulation	regulation	NOUN
ctmj-188	255	3	leads	lead	VERB
ctmj-188	255	4	to	to	ADP
ctmj-188	255	5	the	the	DET
ctmj-188	255	6	modulation	modulation	NOUN
ctmj-188	255	7	of	of	ADP
ctmj-188	255	8	gene	gene	NOUN
ctmj-188	255	9	expressions	expression	NOUN
ctmj-188	255	10	such	such	ADJ
ctmj-188	255	11	as	as	ADP
ctmj-188	255	12	p53	p53	NOUN
ctmj-188	255	13	and	and	CCONJ
ctmj-188	255	14	p21	p21	NOUN
ctmj-188	255	15	,	,	PUNCT
ctmj-188	255	16	resulting	result	VERB
ctmj-188	255	17	in	in	ADP
ctmj-188	255	18	a	a	DET
ctmj-188	255	19	synergistic	synergistic	ADJ
ctmj-188	255	20	inhibition	inhibition	NOUN
ctmj-188	255	21	of	of	ADP
ctmj-188	255	22	crc	crc	NOUN
ctmj-188	255	23	proliferation	proliferation	NOUN
ctmj-188	255	24	.	.	PUNCT
ctmj-188	256	1	moreover	moreover	ADV
ctmj-188	256	2	,	,	PUNCT
ctmj-188	256	3	the	the	DET
ctmj-188	256	4	combination	combination	NOUN
ctmj-188	256	5	therapy	therapy	NOUN
ctmj-188	256	6	modulates	modulate	VERB
ctmj-188	256	7	the	the	DET
ctmj-188	256	8	genes	gene	NOUN
ctmj-188	256	9	expression	expression	NOUN
ctmj-188	256	10	,	,	PUNCT
ctmj-188	256	11	such	such	ADJ
ctmj-188	256	12	as	as	ADP
ctmj-188	256	13	bax	bax	PROPN
ctmj-188	256	14	and	and	CCONJ
ctmj-188	256	15	bcl-2	bcl-2	PROPN
ctmj-188	256	16	,	,	PUNCT
ctmj-188	256	17	leading	lead	VERB
ctmj-188	256	18	to	to	ADP
ctmj-188	256	19	a	a	DET
ctmj-188	256	20	synergistic	synergistic	ADJ
ctmj-188	256	21	induction	induction	NOUN
ctmj-188	256	22	of	of	ADP
ctmj-188	256	23	crc	crc	NOUN
ctmj-188	256	24	apoptosis	apoptosis	NOUN
ctmj-188	256	25	.	.	PUNCT
ctmj-188	257	1	in	in	ADP
ctmj-188	257	2	addition	addition	NOUN
ctmj-188	257	3	,	,	PUNCT
ctmj-188	257	4	it	it	PRON
ctmj-188	257	5	regulates	regulate	VERB
ctmj-188	257	6	the	the	DET
ctmj-188	257	7	emt	emt	PROPN
ctmj-188	257	8	process	process	NOUN
ctmj-188	257	9	,	,	PUNCT
ctmj-188	257	10	synergistically	synergistically	ADV
ctmj-188	257	11	inhibiting	inhibit	VERB
ctmj-188	257	12	crc	crc	NOUN
ctmj-188	257	13	metastasis	metastasis	NOUN
ctmj-188	257	14	.	.	PUNCT
ctmj-188	258	1	furthermore	furthermore	ADV
ctmj-188	258	2	,	,	PUNCT
ctmj-188	258	3	the	the	DET
ctmj-188	258	4	combination	combination	NOUN
ctmj-188	258	5	therapy	therapy	NOUN
ctmj-188	258	6	inhibits	inhibit	VERB
ctmj-188	258	7	the	the	DET
ctmj-188	258	8	expression	expression	NOUN
ctmj-188	258	9	of	of	ADP
ctmj-188	258	10	dpd	dpd	PROPN
ctmj-188	258	11	and	and	CCONJ
ctmj-188	258	12	ts	ts	PROPN
ctmj-188	258	13	,	,	PUNCT
ctmj-188	258	14	which	which	PRON
ctmj-188	258	15	enhances	enhance	VERB
ctmj-188	258	16	the	the	DET
ctmj-188	258	17	efficacy	efficacy	NOUN
ctmj-188	258	18	of	of	ADP
ctmj-188	258	19	5‑fu	5‑fu	PROPN
ctmj-188	258	20	and	and	CCONJ
ctmj-188	258	21	further	far	ADV
ctmj-188	258	22	contributes	contribute	VERB
ctmj-188	258	23	to	to	ADP
ctmj-188	258	24	the	the	DET
ctmj-188	258	25	inhibition	inhibition	NOUN
ctmj-188	258	26	of	of	ADP
ctmj-188	258	27	crc	crc	NOUN
ctmj-188	258	28	progression	progression	NOUN
ctmj-188	258	29	.	.	PUNCT
ctmj-188	259	1	references	reference	NOUN
ctmj-188	259	2	1	1	NUM
ctmj-188	259	3	.	.	PUNCT
ctmj-188	259	4	sung	sung	PROPN
ctmj-188	259	5	h	h	NOUN
ctmj-188	259	6	,	,	PUNCT
ctmj-188	259	7	ferlay	ferlay	PROPN
ctmj-188	259	8	j	j	PROPN
ctmj-188	259	9	,	,	PUNCT
ctmj-188	259	10	siegel	siegel	PROPN
ctmj-188	259	11	rl	rl	PROPN
ctmj-188	259	12	,	,	PUNCT
ctmj-188	259	13	laversanne	laversanne	NOUN
ctmj-188	259	14	m	m	PROPN
ctmj-188	259	15	,	,	PUNCT
ctmj-188	259	16	soerjomataram	soerjomataram	PROPN
ctmj-188	259	17	i	i	PROPN
ctmj-188	259	18	,	,	PUNCT
ctmj-188	259	19	jemal	jemal	PROPN
ctmj-188	259	20	a	a	X
ctmj-188	259	21	,	,	PUNCT
ctmj-188	259	22	et	et	PROPN
ctmj-188	259	23	al	al	PROPN
ctmj-188	259	24	.	.	PUNCT
ctmj-188	260	1	global	global	ADJ
ctmj-188	260	2	cancer	cancer	NOUN
ctmj-188	260	3	statistics	statistic	NOUN
ctmj-188	260	4	2020	2020	NUM
ctmj-188	260	5	:	:	PUNCT
ctmj-188	260	6	globocan	globocan	PROPN
ctmj-188	260	7	estimates	estimate	NOUN
ctmj-188	260	8	of	of	ADP
ctmj-188	260	9	incidence	incidence	NOUN
ctmj-188	260	10	and	and	CCONJ
ctmj-188	260	11	mortality	mortality	NOUN
ctmj-188	260	12	worldwide	worldwide	ADV
ctmj-188	260	13	for	for	ADP
ctmj-188	260	14	36	36	NUM
ctmj-188	260	15	cancers	cancer	NOUN
ctmj-188	260	16	in	in	ADP
ctmj-188	260	17	185	185	NUM
ctmj-188	260	18	countries	country	NOUN
ctmj-188	260	19	.	.	PUNCT
ctmj-188	261	1	ca	can	AUX
ctmj-188	261	2	cancer	cancer	PROPN
ctmj-188	261	3	j	j	PROPN
ctmj-188	261	4	clin	clin	PROPN
ctmj-188	261	5	2021;71:209	2021;71:209	PROPN
ctmj-188	261	6	-	-	PUNCT
ctmj-188	261	7	49	49	NUM
ctmj-188	261	8	.	.	PUNCT
ctmj-188	262	1	2	2	X
ctmj-188	262	2	.	.	X
ctmj-188	262	3	kuipers	kuiper	NOUN
ctmj-188	262	4	ej	ej	PROPN
ctmj-188	262	5	,	,	PUNCT
ctmj-188	262	6	grady	grady	PROPN
ctmj-188	262	7	wm	wm	PROPN
ctmj-188	262	8	,	,	PUNCT
ctmj-188	262	9	lieberman	lieberman	PROPN
ctmj-188	262	10	d	d	PROPN
ctmj-188	262	11	,	,	PUNCT
ctmj-188	262	12	seufferlein	seufferlein	PROPN
ctmj-188	262	13	t	t	PROPN
ctmj-188	262	14	,	,	PUNCT
ctmj-188	262	15	sung	sung	PROPN
ctmj-188	262	16	jj	jj	PROPN
ctmj-188	262	17	,	,	PUNCT
ctmj-188	262	18	boelens	boelen	VERB
ctmj-188	262	19	pg	pg	PROPN
ctmj-188	262	20	,	,	PUNCT
ctmj-188	262	21	et	et	PROPN
ctmj-188	262	22	al	al	PROPN
ctmj-188	262	23	.	.	PROPN
ctmj-188	262	24	colorectal	colorectal	ADJ
ctmj-188	262	25	cancer	cancer	NOUN
ctmj-188	262	26	.	.	PUNCT
ctmj-188	263	1	nat	nat	PROPN
ctmj-188	263	2	rev	rev	VERB
ctmj-188	263	3	dis	dis	PROPN
ctmj-188	263	4	primers	primer	NOUN
ctmj-188	263	5	2015;1:15065	2015;1:15065	NUM
ctmj-188	263	6	.	.	PUNCT
ctmj-188	264	1	3	3	X
ctmj-188	264	2	.	.	X
ctmj-188	264	3	kim	kim	PROPN
ctmj-188	264	4	jh	jh	PROPN
ctmj-188	264	5	.	.	PUNCT
ctmj-188	265	1	chemotherapy	chemotherapy	NOUN
ctmj-188	265	2	for	for	ADP
ctmj-188	265	3	colorectal	colorectal	ADJ
ctmj-188	265	4	cancer	cancer	NOUN
ctmj-188	265	5	in	in	ADP
ctmj-188	265	6	the	the	DET
ctmj-188	265	7	elderly	elderly	ADJ
ctmj-188	265	8	.	.	PUNCT
ctmj-188	266	1	world	world	PROPN
ctmj-188	266	2	j	j	PROPN
ctmj-188	266	3	gastroenterol	gastroenterol	PROPN
ctmj-188	266	4	2015;21:5158‑66	2015;21:5158‑66	NUM
ctmj-188	266	5	.	.	PROPN
ctmj-188	266	6	4	4	NUM
ctmj-188	266	7	.	.	X
ctmj-188	266	8	liao	liao	PROPN
ctmj-188	266	9	hf	hf	PROPN
ctmj-188	266	10	,	,	PUNCT
ctmj-188	266	11	chen	chen	PROPN
ctmj-188	266	12	yj	yj	PROPN
ctmj-188	266	13	,	,	PUNCT
ctmj-188	266	14	yang	yang	PROPN
ctmj-188	266	15	yc	yc	PROPN
ctmj-188	266	16	.	.	PUNCT
ctmj-188	267	1	a	a	DET
ctmj-188	267	2	novel	novel	ADJ
ctmj-188	267	3	polysaccharide	polysaccharide	NOUN
ctmj-188	267	4	of	of	ADP
ctmj-188	267	5	black	black	ADJ
ctmj-188	267	6	soybean	soybean	NOUN
ctmj-188	267	7	promotes	promote	VERB
ctmj-188	267	8	myelopoiesis	myelopoiesis	NOUN
ctmj-188	267	9	and	and	CCONJ
ctmj-188	267	10	reconstitutes	reconstitute	VERB
ctmj-188	267	11	bone	bone	NOUN
ctmj-188	267	12	marrow	marrow	NOUN
ctmj-188	267	13	after	after	ADP
ctmj-188	267	14	5‑flurouracil‑	5‑flurouracil‑	PROPN
ctmj-188	267	15	and	and	CCONJ
ctmj-188	267	16	irradiation‑induced	irradiation‑induce	VERB
ctmj-188	267	17	myelosuppression	myelosuppression	NOUN
ctmj-188	267	18	.	.	PUNCT
ctmj-188	268	1	life	life	NOUN
ctmj-188	268	2	sci	sci	PROPN
ctmj-188	268	3	2005;77:400	2005;77:400	NOUN
ctmj-188	268	4	-	-	SYM
ctmj-188	268	5	13	13	NUM
ctmj-188	268	6	.	.	PUNCT
ctmj-188	268	7	5	5	NUM
ctmj-188	268	8	.	.	X
ctmj-188	268	9	lee	lee	PROPN
ctmj-188	268	10	jj	jj	PROPN
ctmj-188	268	11	,	,	PUNCT
ctmj-188	268	12	beumer	beumer	PROPN
ctmj-188	268	13	jh	jh	PROPN
ctmj-188	268	14	,	,	PUNCT
ctmj-188	268	15	chu	chu	PROPN
ctmj-188	268	16	e.	e.	PROPN
ctmj-188	268	17	therapeutic	therapeutic	ADJ
ctmj-188	268	18	drug	drug	NOUN
ctmj-188	268	19	monitoring	monitoring	NOUN
ctmj-188	268	20	of	of	ADP
ctmj-188	268	21	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	268	22	.	.	PUNCT
ctmj-188	269	1	cancer	cancer	NOUN
ctmj-188	269	2	chemother	chemother	PROPN
ctmj-188	269	3	pharmacol	pharmacol	PROPN
ctmj-188	269	4	2016;78:447‑64	2016;78:447‑64	NUM
ctmj-188	269	5	.	.	PUNCT
ctmj-188	270	1	6	6	NUM
ctmj-188	270	2	.	.	X
ctmj-188	270	3	paschke	paschke	PROPN
ctmj-188	270	4	s	s	PROPN
ctmj-188	270	5	,	,	PUNCT
ctmj-188	270	6	hebart	hebart	PROPN
ctmj-188	270	7	h	h	NOUN
ctmj-188	270	8	,	,	PUNCT
ctmj-188	270	9	goeb	goeb	NOUN
ctmj-188	270	10	r	r	NOUN
ctmj-188	270	11	,	,	PUNCT
ctmj-188	270	12	staib	staib	NOUN
ctmj-188	270	13	l	l	NOUN
ctmj-188	270	14	,	,	PUNCT
ctmj-188	270	15	fleck	fleck	NOUN
ctmj-188	270	16	u	u	NOUN
ctmj-188	270	17	,	,	PUNCT
ctmj-188	270	18	henne‑bruns	henne‑brun	NOUN
ctmj-188	270	19	d	d	NOUN
ctmj-188	270	20	,	,	PUNCT
ctmj-188	270	21	et	et	PROPN
ctmj-188	270	22	al	al	PROPN
ctmj-188	270	23	.	.	PROPN
ctmj-188	270	24	adjuvant	adjuvant	PROPN
ctmj-188	270	25	chemotherapy	chemotherapy	NOUN
ctmj-188	270	26	of	of	ADP
ctmj-188	270	27	locally	locally	ADV
ctmj-188	270	28	advanced	advanced	ADJ
ctmj-188	270	29	colon	colon	NOUN
ctmj-188	270	30	cancer	cancer	NOUN
ctmj-188	270	31	:	:	PUNCT
ctmj-188	270	32	final	final	ADJ
ctmj-188	270	33	results	result	NOUN
ctmj-188	270	34	of	of	ADP
ctmj-188	270	35	a	a	DET
ctmj-188	270	36	randomized	randomized	ADJ
ctmj-188	270	37	trial	trial	NOUN
ctmj-188	270	38	comparing	compare	VERB
ctmj-188	270	39	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	270	40	and	and	CCONJ
ctmj-188	270	41	folinic	folinic	ADJ
ctmj-188	270	42	acid	acid	NOUN
ctmj-188	270	43	with	with	ADP
ctmj-188	270	44	folfiri	folfiri	PROPN
ctmj-188	270	45	.	.	PUNCT
ctmj-188	271	1	visc	visc	PROPN
ctmj-188	271	2	med	me	VERB
ctmj-188	271	3	2019;35:124‑32	2019;35:124‑32	NUM
ctmj-188	271	4	.	.	PUNCT
ctmj-188	272	1	7	7	NUM
ctmj-188	272	2	.	.	X
ctmj-188	272	3	zhang	zhang	PROPN
ctmj-188	272	4	jh	jh	PROPN
ctmj-188	272	5	,	,	PUNCT
ctmj-188	272	6	wang	wang	PROPN
ctmj-188	272	7	lh	lh	PROPN
ctmj-188	272	8	,	,	PUNCT
ctmj-188	272	9	li	li	PROPN
ctmj-188	272	10	xj	xj	PROPN
ctmj-188	272	11	,	,	PUNCT
ctmj-188	272	12	wang	wang	PROPN
ctmj-188	272	13	ap	ap	PROPN
ctmj-188	272	14	,	,	PUNCT
ctmj-188	272	15	reng	reng	PROPN
ctmj-188	272	16	lq	lq	PROPN
ctmj-188	272	17	,	,	PUNCT
ctmj-188	272	18	xia	xia	PROPN
ctmj-188	272	19	fg	fg	PROPN
ctmj-188	272	20	,	,	PUNCT
ctmj-188	272	21	et	et	PROPN
ctmj-188	272	22	al	al	PROPN
ctmj-188	272	23	.	.	PUNCT
ctmj-188	272	24	expression	expression	NOUN
ctmj-188	272	25	of	of	ADP
ctmj-188	272	26	ang‑2	ang‑2	ADJ
ctmj-188	272	27	/	/	SYM
ctmj-188	272	28	tie‑2	tie‑2	NOUN
ctmj-188	272	29	and	and	CCONJ
ctmj-188	272	30	pi3k	pi3k	PROPN
ctmj-188	272	31	/	/	SYM
ctmj-188	272	32	akt	akt	PROPN
ctmj-188	272	33	in	in	ADP
ctmj-188	272	34	colorectal	colorectal	ADJ
ctmj-188	272	35	cancer	cancer	NOUN
ctmj-188	272	36	.	.	PUNCT
ctmj-188	273	1	asian	asian	PROPN
ctmj-188	273	2	pac	pac	PROPN
ctmj-188	273	3	j	j	PROPN
ctmj-188	273	4	cancer	cancer	PROPN
ctmj-188	273	5	prev	prev	X
ctmj-188	273	6	2014;15:8651‑6	2014;15:8651‑6	ADJ
ctmj-188	273	7	.	.	PUNCT
ctmj-188	274	1	8	8	X
ctmj-188	274	2	.	.	PUNCT
ctmj-188	275	1	mondal	mondal	PROPN
ctmj-188	275	2	p	p	PROPN
ctmj-188	275	3	,	,	PUNCT
ctmj-188	275	4	natesh	natesh	PROPN
ctmj-188	275	5	j	j	PROPN
ctmj-188	275	6	,	,	PUNCT
ctmj-188	275	7	penta	penta	PROPN
ctmj-188	275	8	d	d	PROPN
ctmj-188	275	9	,	,	PUNCT
ctmj-188	275	10	meeran	meeran	VERB
ctmj-188	275	11	sm	sm	PROPN
ctmj-188	275	12	.	.	PROPN
ctmj-188	275	13	extract	extract	NOUN
ctmj-188	275	14	of	of	ADP
ctmj-188	275	15	murraya	murraya	NOUN
ctmj-188	275	16	koenigii	koenigii	PROPN
ctmj-188	275	17	selectively	selectively	ADV
ctmj-188	275	18	causes	cause	VERB
ctmj-188	275	19	genomic	genomic	ADJ
ctmj-188	275	20	instability	instability	NOUN
ctmj-188	275	21	by	by	ADP
ctmj-188	275	22	altering	alter	VERB
ctmj-188	275	23	redox	redox	NOUN
ctmj-188	275	24	-	-	PUNCT
ctmj-188	275	25	status	status	NOUN
ctmj-188	275	26	via	via	ADP
ctmj-188	275	27	targeting	target	VERB
ctmj-188	275	28	pi3k	pi3k	PROPN
ctmj-188	275	29	/	/	SYM
ctmj-188	275	30	akt	akt	PROPN
ctmj-188	275	31	/	/	SYM
ctmj-188	275	32	nrf2	nrf2	PROPN
ctmj-188	275	33	/	/	SYM
ctmj-188	275	34	caspase‑3	caspase‑3	PROPN
ctmj-188	275	35	signaling	signal	VERB
ctmj-188	275	36	pathway	pathway	NOUN
ctmj-188	275	37	in	in	ADP
ctmj-188	275	38	human	human	ADJ
ctmj-188	275	39	non‑small	non‑small	PRON
ctmj-188	275	40	cell	cell	NOUN
ctmj-188	275	41	lung	lung	NOUN
ctmj-188	275	42	cancer	cancer	NOUN
ctmj-188	275	43	.	.	PUNCT
ctmj-188	276	1	phytomedicine	phytomedicine	PROPN
ctmj-188	276	2	2022;104:154272	2022;104:154272	NUM
ctmj-188	276	3	.	.	PUNCT
ctmj-188	277	1	9	9	NUM
ctmj-188	277	2	.	.	PUNCT
ctmj-188	277	3	wang	wang	PROPN
ctmj-188	277	4	y	y	PROPN
ctmj-188	277	5	,	,	PUNCT
ctmj-188	277	6	zhang	zhang	PROPN
ctmj-188	277	7	s	s	PROPN
ctmj-188	277	8	,	,	PUNCT
ctmj-188	277	9	liu	liu	PROPN
ctmj-188	277	10	j	j	PROPN
ctmj-188	277	11	,	,	PUNCT
ctmj-188	277	12	fang	fang	PROPN
ctmj-188	277	13	b	b	PROPN
ctmj-188	277	14	,	,	PUNCT
ctmj-188	277	15	yao	yao	PROPN
ctmj-188	277	16	j	j	PROPN
ctmj-188	277	17	,	,	PUNCT
ctmj-188	277	18	cheng	cheng	PROPN
ctmj-188	277	19	b.	b.	PROPN
ctmj-188	277	20	matrine	matrine	PROPN
ctmj-188	277	21	inhibits	inhibit	VERB
ctmj-188	277	22	the	the	DET
ctmj-188	277	23	invasive	invasive	ADJ
ctmj-188	277	24	and	and	CCONJ
ctmj-188	277	25	migratory	migratory	NOUN
ctmj-188	277	26	properties	property	NOUN
ctmj-188	277	27	of	of	ADP
ctmj-188	277	28	human	human	ADJ
ctmj-188	277	29	hepatocellular	hepatocellular	ADJ
ctmj-188	277	30	carcinoma	carcinoma	NOUN
ctmj-188	277	31	by	by	ADP
ctmj-188	277	32	regulating	regulate	VERB
ctmj-188	277	33	epithelial	epithelial	ADJ
ctmj-188	277	34	-	-	PUNCT
ctmj-188	277	35	mesenchymal	mesenchymal	NOUN
ctmj-188	277	36	transition	transition	NOUN
ctmj-188	277	37	.	.	PUNCT
ctmj-188	278	1	mol	mol	ADP
ctmj-188	278	2	med	med	PROPN
ctmj-188	278	3	rep	rep	PROPN
ctmj-188	278	4	2018;18:911	2018;18:911	PROPN
ctmj-188	278	5	-	-	SYM
ctmj-188	278	6	9	9	NUM
ctmj-188	278	7	.	.	NOUN
ctmj-188	278	8	10	10	NUM
ctmj-188	278	9	.	.	PUNCT
ctmj-188	279	1	dong	dong	PROPN
ctmj-188	279	2	s	s	PROPN
ctmj-188	279	3	,	,	PUNCT
ctmj-188	279	4	liang	liang	PROPN
ctmj-188	279	5	s	s	PROPN
ctmj-188	279	6	,	,	PUNCT
ctmj-188	279	7	cheng	cheng	PROPN
ctmj-188	279	8	z	z	PROPN
ctmj-188	279	9	,	,	PUNCT
ctmj-188	279	10	zhang	zhang	PROPN
ctmj-188	279	11	x	x	PROPN
ctmj-188	279	12	,	,	PUNCT
ctmj-188	279	13	luo	luo	PROPN
ctmj-188	279	14	l	l	PROPN
ctmj-188	279	15	,	,	PUNCT
ctmj-188	279	16	li	li	PROPN
ctmj-188	279	17	l	l	PROPN
ctmj-188	279	18	,	,	PUNCT
ctmj-188	279	19	et	et	PROPN
ctmj-188	279	20	al	al	PROPN
ctmj-188	279	21	.	.	PUNCT
ctmj-188	280	1	ros	ros	PROPN
ctmj-188	280	2	/	/	SYM
ctmj-188	280	3	pi3k/	pi3k/	PROPN
ctmj-188	280	4	akt	akt	PROPN
ctmj-188	280	5	and	and	CCONJ
ctmj-188	280	6	wnt	wnt	PROPN
ctmj-188	280	7	/	/	SYM
ctmj-188	280	8	β‑catenin	β‑catenin	PROPN
ctmj-188	280	9	signalings	signaling	NOUN
ctmj-188	280	10	activate	activate	VERB
ctmj-188	280	11	hif‑1α‑induced	hif‑1α‑induce	VERB
ctmj-188	280	12	metabolic	metabolic	NOUN
ctmj-188	280	13	reprogramming	reprogramme	VERB
ctmj-188	280	14	to	to	PART
ctmj-188	280	15	impart	impart	VERB
ctmj-188	280	16	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	280	17	resistance	resistance	NOUN
ctmj-188	280	18	in	in	ADP
ctmj-188	280	19	colorectal	colorectal	ADJ
ctmj-188	280	20	cancer	cancer	NOUN
ctmj-188	280	21	.	.	PUNCT
ctmj-188	281	1	j	j	PROPN
ctmj-188	281	2	exp	exp	PROPN
ctmj-188	281	3	clin	clin	PROPN
ctmj-188	281	4	cancer	cancer	NOUN
ctmj-188	281	5	res	re	VERB
ctmj-188	281	6	2022;41:15	2022;41:15	NUM
ctmj-188	281	7	.	.	PUNCT
ctmj-188	282	1	11	11	NUM
ctmj-188	282	2	.	.	PUNCT
ctmj-188	283	1	ma	ma	PROPN
ctmj-188	283	2	z	z	PROPN
ctmj-188	283	3	,	,	PUNCT
ctmj-188	283	4	lou	lou	PROPN
ctmj-188	283	5	s	s	PROPN
ctmj-188	283	6	,	,	PUNCT
ctmj-188	283	7	jiang	jiang	PROPN
ctmj-188	283	8	z.	z.	PROPN
ctmj-188	283	9	phlda2	phlda2	PROPN
ctmj-188	283	10	regulates	regulate	VERB
ctmj-188	283	11	emt	emt	NOUN
ctmj-188	283	12	and	and	CCONJ
ctmj-188	283	13	autophagy	autophagy	VERB
ctmj-188	283	14	in	in	ADP
ctmj-188	283	15	colorectal	colorectal	ADJ
ctmj-188	283	16	cancer	cancer	NOUN
ctmj-188	283	17	via	via	ADP
ctmj-188	283	18	the	the	DET
ctmj-188	283	19	pi3k	pi3k	PROPN
ctmj-188	283	20	/	/	SYM
ctmj-188	283	21	akt	akt	PROPN
ctmj-188	283	22	signaling	signal	VERB
ctmj-188	283	23	pathway	pathway	NOUN
ctmj-188	283	24	.	.	PUNCT
ctmj-188	284	1	aging	age	VERB
ctmj-188	284	2	(	(	PUNCT
ctmj-188	284	3	albany	albany	PROPN
ctmj-188	284	4	ny	ny	PROPN
ctmj-188	284	5	)	)	PUNCT
ctmj-188	284	6	2020;12:7985‑8000	2020;12:7985‑8000	NUM
ctmj-188	284	7	.	.	PROPN
ctmj-188	284	8	12	12	NUM
ctmj-188	284	9	.	.	PUNCT
ctmj-188	285	1	tallarida	tallarida	PROPN
ctmj-188	285	2	rj	rj	PROPN
ctmj-188	285	3	,	,	PUNCT
ctmj-188	285	4	midic	midic	PROPN
ctmj-188	285	5	u	u	NOUN
ctmj-188	285	6	,	,	PUNCT
ctmj-188	285	7	lamarre	lamarre	ADJ
ctmj-188	285	8	ns	ns	ADJ
ctmj-188	285	9	,	,	PUNCT
ctmj-188	285	10	obradovic	obradovic	ADJ
ctmj-188	285	11	z.	z.	PROPN
ctmj-188	285	12	a	a	DET
ctmj-188	285	13	search	search	NOUN
ctmj-188	285	14	for	for	ADP
ctmj-188	285	15	interaction	interaction	NOUN
ctmj-188	285	16	among	among	ADP
ctmj-188	285	17	combinations	combination	NOUN
ctmj-188	285	18	of	of	ADP
ctmj-188	285	19	drugs	drug	NOUN
ctmj-188	285	20	of	of	ADP
ctmj-188	285	21	abuse	abuse	NOUN
ctmj-188	285	22	and	and	CCONJ
ctmj-188	285	23	the	the	DET
ctmj-188	285	24	use	use	NOUN
ctmj-188	285	25	of	of	ADP
ctmj-188	285	26	isobolographic	isobolographic	ADJ
ctmj-188	285	27	analysis	analysis	NOUN
ctmj-188	285	28	.	.	PUNCT
ctmj-188	286	1	j	j	PROPN
ctmj-188	286	2	clin	clin	PROPN
ctmj-188	286	3	pharm	pharm	PROPN
ctmj-188	286	4	ther	ther	ADV
ctmj-188	286	5	2013;38:190‑5	2013;38:190‑5	NUM
ctmj-188	286	6	.	.	PUNCT
ctmj-188	287	1	13	13	NUM
ctmj-188	287	2	.	.	PUNCT
ctmj-188	288	1	yang	yang	PROPN
ctmj-188	288	2	h	h	PROPN
ctmj-188	288	3	,	,	PUNCT
ctmj-188	288	4	liu	liu	PROPN
ctmj-188	288	5	jx	jx	PROPN
ctmj-188	288	6	,	,	PUNCT
ctmj-188	288	7	shang	shang	PROPN
ctmj-188	288	8	hx	hx	PROPN
ctmj-188	288	9	,	,	PUNCT
ctmj-188	288	10	lin	lin	PROPN
ctmj-188	288	11	s	s	PROPN
ctmj-188	288	12	,	,	PUNCT
ctmj-188	288	13	zhao	zhao	PROPN
ctmj-188	288	14	jy	jy	PROPN
ctmj-188	288	15	,	,	PUNCT
ctmj-188	288	16	lin	lin	PROPN
ctmj-188	288	17	jm	jm	PROPN
ctmj-188	288	18	.	.	PROPN
ctmj-188	288	19	qingjie	qingjie	PROPN
ctmj-188	288	20	fuzheng	fuzheng	PROPN
ctmj-188	288	21	granules	granule	NOUN
ctmj-188	288	22	inhibit	inhibit	VERB
ctmj-188	288	23	colorectal	colorectal	ADJ
ctmj-188	288	24	cancer	cancer	NOUN
ctmj-188	288	25	cell	cell	NOUN
ctmj-188	288	26	growth	growth	NOUN
ctmj-188	288	27	by	by	ADP
ctmj-188	288	28	the	the	DET
ctmj-188	288	29	pi3k	pi3k	PROPN
ctmj-188	288	30	/	/	SYM
ctmj-188	288	31	akt	akt	PROPN
ctmj-188	288	32	and	and	CCONJ
ctmj-188	288	33	erk	erk	PROPN
ctmj-188	288	34	pathways	pathway	NOUN
ctmj-188	288	35	.	.	PUNCT
ctmj-188	289	1	world	world	PROPN
ctmj-188	289	2	j	j	PROPN
ctmj-188	289	3	gastrointest	gastroint	ADJ
ctmj-188	289	4	oncol	oncol	ADJ
ctmj-188	289	5	2019;11:377‑92	2019;11:377‑92	NUM
ctmj-188	289	6	.	.	PUNCT
ctmj-188	290	1	14	14	NUM
ctmj-188	290	2	.	.	PUNCT
ctmj-188	291	1	zhang	zhang	PROPN
ctmj-188	291	2	l	l	PROPN
ctmj-188	291	3	,	,	PUNCT
ctmj-188	291	4	jin	jin	PROPN
ctmj-188	291	5	y	y	PROPN
ctmj-188	291	6	,	,	PUNCT
ctmj-188	291	7	peng	peng	PROPN
ctmj-188	291	8	j	j	PROPN
ctmj-188	291	9	,	,	PUNCT
ctmj-188	291	10	chen	chen	PROPN
ctmj-188	291	11	w	w	PROPN
ctmj-188	291	12	,	,	PUNCT
ctmj-188	291	13	lisha	lisha	PROPN
ctmj-188	291	14	l	l	PROPN
ctmj-188	291	15	,	,	PUNCT
ctmj-188	291	16	lin	lin	PROPN
ctmj-188	291	17	j.	j.	PROPN
ctmj-188	291	18	qingjie	qingjie	PROPN
ctmj-188	291	19	fuzheng	fuzheng	PROPN
ctmj-188	291	20	granule	granule	PROPN
ctmj-188	291	21	attenuates	attenuate	VERB
ctmj-188	291	22	5‑fluorouracil‑induced	5‑fluorouracil‑induce	VERB
ctmj-188	291	23	intestinal	intestinal	ADJ
ctmj-188	291	24	mucosal	mucosal	NOUN
ctmj-188	291	25	damage	damage	NOUN
ctmj-188	291	26	.	.	PUNCT
ctmj-188	292	1	biomed	biome	VERB
ctmj-188	292	2	pharmacother	pharmacother	ADJ
ctmj-188	292	3	2019;118:109223	2019;118:109223	NUM
ctmj-188	292	4	.	.	PUNCT
ctmj-188	293	1	15	15	NUM
ctmj-188	293	2	.	.	PUNCT
ctmj-188	294	1	chou	chou	PROPN
ctmj-188	294	2	tc	tc	PROPN
ctmj-188	294	3	.	.	PROPN
ctmj-188	294	4	drug	drug	NOUN
ctmj-188	294	5	combination	combination	NOUN
ctmj-188	294	6	studies	study	NOUN
ctmj-188	294	7	and	and	CCONJ
ctmj-188	294	8	their	their	PRON
ctmj-188	294	9	synergy	synergy	NOUN
ctmj-188	294	10	quantification	quantification	NOUN
ctmj-188	294	11	using	use	VERB
ctmj-188	294	12	the	the	DET
ctmj-188	294	13	chou	chou	NOUN
ctmj-188	294	14	-	-	PUNCT
ctmj-188	294	15	talalay	talalay	NOUN
ctmj-188	294	16	method	method	NOUN
ctmj-188	294	17	.	.	PUNCT
ctmj-188	295	1	cancer	cancer	NOUN
ctmj-188	295	2	res	re	NOUN
ctmj-188	295	3	2010;70:440	2010;70:440	PROPN
ctmj-188	295	4	-	-	SYM
ctmj-188	295	5	6	6	NUM
ctmj-188	295	6	.	.	NOUN
ctmj-188	295	7	16	16	NUM
ctmj-188	295	8	.	.	PUNCT
ctmj-188	296	1	fearon	fearon	PROPN
ctmj-188	296	2	er	er	INTJ
ctmj-188	296	3	.	.	PUNCT
ctmj-188	297	1	molecular	molecular	ADJ
ctmj-188	297	2	genetics	genetic	NOUN
ctmj-188	297	3	of	of	ADP
ctmj-188	297	4	colorectal	colorectal	ADJ
ctmj-188	297	5	cancer	cancer	NOUN
ctmj-188	297	6	.	.	PUNCT
ctmj-188	298	1	annu	annu	PROPN
ctmj-188	298	2	rev	rev	PROPN
ctmj-188	298	3	pathol	pathol	PROPN
ctmj-188	298	4	2011;6:479	2011;6:479	PROPN
ctmj-188	298	5	-	-	PUNCT
ctmj-188	298	6	507	507	NUM
ctmj-188	298	7	.	.	PUNCT
ctmj-188	299	1	17	17	NUM
ctmj-188	299	2	.	.	PUNCT
ctmj-188	300	1	liu	liu	PROPN
ctmj-188	300	2	x	x	PROPN
ctmj-188	300	3	,	,	PUNCT
ctmj-188	300	4	liu	liu	PROPN
ctmj-188	300	5	y	y	PROPN
ctmj-188	300	6	,	,	PUNCT
ctmj-188	300	7	liu	liu	PROPN
ctmj-188	300	8	z	z	PROPN
ctmj-188	300	9	,	,	PUNCT
ctmj-188	300	10	lin	lin	PROPN
ctmj-188	300	11	c	c	PROPN
ctmj-188	300	12	,	,	PUNCT
ctmj-188	300	13	meng	meng	PROPN
ctmj-188	300	14	f	f	PROPN
ctmj-188	300	15	,	,	PUNCT
ctmj-188	300	16	xu	xu	PROPN
ctmj-188	300	17	l	l	PROPN
ctmj-188	300	18	,	,	PUNCT
ctmj-188	300	19	et	et	PROPN
ctmj-188	300	20	al	al	PROPN
ctmj-188	300	21	.	.	PUNCT
ctmj-188	301	1	circmyh9	circmyh9	PROPN
ctmj-188	301	2	drives	drive	VERB
ctmj-188	301	3	colorectal	colorectal	ADJ
ctmj-188	301	4	cancer	cancer	NOUN
ctmj-188	301	5	growth	growth	NOUN
ctmj-188	301	6	by	by	ADP
ctmj-188	301	7	regulating	regulate	VERB
ctmj-188	301	8	serine	serine	NOUN
ctmj-188	301	9	metabolism	metabolism	NOUN
ctmj-188	301	10	and	and	CCONJ
ctmj-188	301	11	redox	redox	ADJ
ctmj-188	301	12	homeostasis	homeostasis	NOUN
ctmj-188	301	13	in	in	ADP
ctmj-188	301	14	a	a	DET
ctmj-188	301	15	p53	p53	NOUN
ctmj-188	301	16	-	-	PUNCT
ctmj-188	301	17	dependent	dependent	ADJ
ctmj-188	301	18	manner	manner	NOUN
ctmj-188	301	19	.	.	PUNCT
ctmj-188	302	1	mol	mol	ADP
ctmj-188	302	2	cancer	cancer	NOUN
ctmj-188	302	3	2021;20:114	2021;20:114	PROPN
ctmj-188	302	4	.	.	PROPN
ctmj-188	302	5	18	18	NUM
ctmj-188	302	6	.	.	PUNCT
ctmj-188	303	1	chen	chen	PROPN
ctmj-188	303	2	z	z	PROPN
ctmj-188	303	3	,	,	PUNCT
ctmj-188	303	4	hou	hou	PROPN
ctmj-188	303	5	r	r	PROPN
ctmj-188	303	6	,	,	PUNCT
ctmj-188	303	7	gao	gao	PROPN
ctmj-188	303	8	s	s	PROPN
ctmj-188	303	9	,	,	PUNCT
ctmj-188	303	10	song	song	NOUN
ctmj-188	303	11	d	d	PROPN
ctmj-188	303	12	,	,	PUNCT
ctmj-188	303	13	feng	feng	PROPN
ctmj-188	303	14	y.	y.	PROPN
ctmj-188	303	15	baicalein	baicalein	PROPN
ctmj-188	303	16	inhibits	inhibit	VERB
ctmj-188	303	17	proliferation	proliferation	NOUN
ctmj-188	303	18	activity	activity	NOUN
ctmj-188	303	19	of	of	ADP
ctmj-188	303	20	human	human	ADJ
ctmj-188	303	21	colorectal	colorectal	ADJ
ctmj-188	303	22	cancer	cancer	NOUN
ctmj-188	303	23	cells	cell	NOUN
ctmj-188	303	24	hct116	hct116	ADV
ctmj-188	303	25	through	through	ADP
ctmj-188	303	26	downregulation	downregulation	NOUN
ctmj-188	303	27	of	of	ADP
ctmj-188	303	28	ezrin	ezrin	NOUN
ctmj-188	303	29	.	.	PUNCT
ctmj-188	304	1	cell	cell	NOUN
ctmj-188	304	2	physiol	physiol	PROPN
ctmj-188	304	3	biochem	biochem	PROPN
ctmj-188	304	4	2018;49:2035‑46	2018;49:2035‑46	NUM
ctmj-188	304	5	.	.	PROPN
ctmj-188	304	6	19	19	NUM
ctmj-188	304	7	.	.	PUNCT
ctmj-188	305	1	bey	bey	PROPN
ctmj-188	305	2	c	c	PROPN
ctmj-188	305	3	,	,	PUNCT
ctmj-188	305	4	yong	yong	PROPN
ctmj-188	305	5	x	x	PROPN
ctmj-188	305	6	,	,	PUNCT
ctmj-188	305	7	eu	eu	PROPN
ctmj-188	305	8	v	v	PROPN
ctmj-188	305	9	,	,	PUNCT
ctmj-188	305	10	hong	hong	PROPN
ctmj-188	305	11	z.	z.	PROPN
ctmj-188	305	12	role	role	NOUN
ctmj-188	305	13	of	of	ADP
ctmj-188	305	14	p53	p53	NOUN
ctmj-188	305	15	and	and	CCONJ
ctmj-188	305	16	p21	p21	NOUN
ctmj-188	305	17	in	in	ADP
ctmj-188	305	18	senescence	senescence	NOUN
ctmj-188	305	19	-	-	PUNCT
ctmj-188	305	20	like	like	ADJ
ctmj-188	305	21	terminal	terminal	ADJ
ctmj-188	305	22	proliferation	proliferation	NOUN
ctmj-188	305	23	arrest	arrest	NOUN
ctmj-188	305	24	induced	induce	VERB
ctmj-188	305	25	in	in	ADP
ctmj-188	305	26	human	human	ADJ
ctmj-188	305	27	tumor	tumor	NOUN
ctmj-188	305	28	cells	cell	NOUN
ctmj-188	305	29	by	by	ADP
ctmj-188	305	30	chemotherapeutic	chemotherapeutic	ADJ
ctmj-188	305	31	drugs	drug	NOUN
ctmj-188	305	32	.	.	PUNCT
ctmj-188	306	1	oncogene	oncogene	NOUN
ctmj-188	306	2	1999;18:3012	1999;18:3012	NUM
ctmj-188	306	3	-	-	SYM
ctmj-188	306	4	9	9	NUM
ctmj-188	306	5	.	.	NOUN
ctmj-188	306	6	20	20	NUM
ctmj-188	306	7	.	.	PUNCT
ctmj-188	307	1	schade	schade	PROPN
ctmj-188	307	2	ae	ae	PROPN
ctmj-188	307	3	,	,	PUNCT
ctmj-188	307	4	oser	oser	PROPN
ctmj-188	307	5	mg	mg	PROPN
ctmj-188	307	6	,	,	PUNCT
ctmj-188	307	7	nicholson	nicholson	PROPN
ctmj-188	307	8	he	he	PRON
ctmj-188	307	9	,	,	PUNCT
ctmj-188	307	10	decaprio	decaprio	PROPN
ctmj-188	307	11	ja	ja	PROPN
ctmj-188	307	12	.	.	PUNCT
ctmj-188	308	1	cyclin	cyclin	PROPN
ctmj-188	308	2	d‑cdk4	d‑cdk4	PROPN
ctmj-188	308	3	relieves	relieve	VERB
ctmj-188	308	4	cooperative	cooperative	ADJ
ctmj-188	308	5	repression	repression	NOUN
ctmj-188	308	6	of	of	ADP
ctmj-188	308	7	proliferation	proliferation	NOUN
ctmj-188	308	8	and	and	CCONJ
ctmj-188	308	9	cell	cell	NOUN
ctmj-188	308	10	cycle	cycle	NOUN
ctmj-188	308	11	gene	gene	NOUN
ctmj-188	308	12	expression	expression	NOUN
ctmj-188	308	13	by	by	ADP
ctmj-188	308	14	dream	dream	NOUN
ctmj-188	308	15	and	and	CCONJ
ctmj-188	308	16	rb	rb	NOUN
ctmj-188	308	17	.	.	PUNCT
ctmj-188	309	1	oncogene	oncogene	NOUN
ctmj-188	309	2	2019;38:4962	2019;38:4962	NUM
ctmj-188	309	3	-	-	SYM
ctmj-188	309	4	76	76	NUM
ctmj-188	309	5	.	.	PUNCT
ctmj-188	310	1	21	21	NUM
ctmj-188	310	2	.	.	PUNCT
ctmj-188	311	1	xia	xia	PROPN
ctmj-188	311	2	y	y	PROPN
ctmj-188	311	3	,	,	PUNCT
ctmj-188	311	4	deng	deng	PROPN
ctmj-188	311	5	y	y	PROPN
ctmj-188	311	6	,	,	PUNCT
ctmj-188	311	7	zhou	zhou	PROPN
ctmj-188	311	8	y	y	PROPN
ctmj-188	311	9	,	,	PUNCT
ctmj-188	311	10	li	li	PROPN
ctmj-188	311	11	d	d	PROPN
ctmj-188	311	12	,	,	PUNCT
ctmj-188	311	13	sun	sun	PROPN
ctmj-188	311	14	x	x	SYM
ctmj-188	311	15	,	,	PUNCT
ctmj-188	311	16	gu	gu	NOUN
ctmj-188	311	17	l	l	PROPN
ctmj-188	311	18	,	,	PUNCT
ctmj-188	311	19	et	et	PROPN
ctmj-188	311	20	al	al	PROPN
ctmj-188	311	21	.	.	PROPN
ctmj-188	311	22	tspan31	tspan31	PROPN
ctmj-188	311	23	suppresses	suppress	VERB
ctmj-188	311	24	cell	cell	NOUN
ctmj-188	311	25	proliferation	proliferation	NOUN
ctmj-188	311	26	in	in	ADP
ctmj-188	311	27	human	human	ADJ
ctmj-188	311	28	cervical	cervical	ADJ
ctmj-188	311	29	cancer	cancer	NOUN
ctmj-188	311	30	through	through	ADP
ctmj-188	311	31	down	down	ADJ
ctmj-188	311	32	-	-	PUNCT
ctmj-188	311	33	regulation	regulation	NOUN
ctmj-188	311	34	of	of	ADP
ctmj-188	311	35	its	its	PRON
ctmj-188	311	36	antisense	antisense	NOUN
ctmj-188	311	37	pairing	pair	VERB
ctmj-188	311	38	with	with	ADP
ctmj-188	311	39	cdk4	cdk4	NOUN
ctmj-188	311	40	.	.	PUNCT
ctmj-188	312	1	cell	cell	NOUN
ctmj-188	312	2	biochem	biochem	PROPN
ctmj-188	312	3	funct	funct	VERB
ctmj-188	312	4	2020;38:660	2020;38:660	NOUN
ctmj-188	312	5	-	-	SYM
ctmj-188	312	6	8	8	NUM
ctmj-188	312	7	.	.	PUNCT
ctmj-188	313	1	22	22	NUM
ctmj-188	313	2	.	.	PUNCT
ctmj-188	314	1	zhang	zhang	PROPN
ctmj-188	314	2	y	y	PROPN
ctmj-188	314	3	,	,	PUNCT
ctmj-188	314	4	yang	yang	PROPN
ctmj-188	314	5	x	x	PROPN
ctmj-188	314	6	,	,	PUNCT
ctmj-188	314	7	ge	ge	PROPN
ctmj-188	314	8	x	x	PROPN
ctmj-188	314	9	,	,	PUNCT
ctmj-188	314	10	zhang	zhang	PROPN
ctmj-188	314	11	f.	f.	PROPN
ctmj-188	314	12	puerarin	puerarin	PROPN
ctmj-188	314	13	attenuates	attenuate	VERB
ctmj-188	314	14	neurological	neurological	ADJ
ctmj-188	314	15	deficits	deficit	NOUN
ctmj-188	314	16	via	via	ADP
ctmj-188	314	17	bcl‑2	bcl‑2	NOUN
ctmj-188	314	18	/	/	SYM
ctmj-188	314	19	bax	bax	PROPN
ctmj-188	314	20	/	/	SYM
ctmj-188	314	21	cleaved	cleaved	ADJ
ctmj-188	314	22	caspase‑3	caspase‑3	PROPN
ctmj-188	314	23	and	and	CCONJ
ctmj-188	314	24	sirt3	sirt3	PROPN
ctmj-188	314	25	/	/	SYM
ctmj-188	314	26	sod2	sod2	PROPN
ctmj-188	314	27	apoptotic	apoptotic	ADJ
ctmj-188	314	28	pathways	pathway	NOUN
ctmj-188	314	29	in	in	ADP
ctmj-188	314	30	subarachnoid	subarachnoid	VERB
ctmj-188	314	31	hemorrhage	hemorrhage	NOUN
ctmj-188	314	32	mice	mouse	NOUN
ctmj-188	314	33	.	.	PUNCT
ctmj-188	315	1	biomed	biome	VERB
ctmj-188	315	2	pharmacother	pharmacother	ADJ
ctmj-188	315	3	2019;109:726	2019;109:726	NUM
ctmj-188	315	4	-	-	SYM
ctmj-188	315	5	33	33	NUM
ctmj-188	315	6	.	.	PUNCT
ctmj-188	316	1	23	23	NUM
ctmj-188	316	2	.	.	PUNCT
ctmj-188	317	1	hassan	hassan	PROPN
ctmj-188	317	2	m	m	PROPN
ctmj-188	317	3	,	,	PUNCT
ctmj-188	317	4	watari	watari	PROPN
ctmj-188	317	5	h	h	PROPN
ctmj-188	317	6	,	,	PUNCT
ctmj-188	317	7	abualmaaty	abualmaaty	NOUN
ctmj-188	317	8	a	a	PRON
ctmj-188	317	9	,	,	PUNCT
ctmj-188	317	10	ohba	ohba	ADJ
ctmj-188	317	11	y	y	NOUN
ctmj-188	317	12	,	,	PUNCT
ctmj-188	317	13	sakuragi	sakuragi	NOUN
ctmj-188	317	14	n.	n.	NOUN
ctmj-188	317	15	apoptosis	apoptosis	NOUN
ctmj-188	317	16	and	and	CCONJ
ctmj-188	317	17	molecular	molecular	ADJ
ctmj-188	317	18	targeting	targeting	NOUN
ctmj-188	317	19	therapy	therapy	NOUN
ctmj-188	317	20	in	in	ADP
ctmj-188	317	21	cancer	cancer	NOUN
ctmj-188	317	22	.	.	PUNCT
ctmj-188	318	1	biomed	biome	VERB
ctmj-188	318	2	res	re	NOUN
ctmj-188	318	3	int	int	NOUN
ctmj-188	318	4	2014;2014:150845	2014;2014:150845	NUM
ctmj-188	318	5	.	.	PROPN
ctmj-188	318	6	24	24	NUM
ctmj-188	318	7	.	.	PUNCT
ctmj-188	319	1	li	li	PROPN
ctmj-188	319	2	y	y	PROPN
ctmj-188	319	3	,	,	PUNCT
ctmj-188	319	4	wang	wang	PROPN
ctmj-188	319	5	y	y	PROPN
ctmj-188	319	6	,	,	PUNCT
ctmj-188	319	7	yu	yu	PROPN
ctmj-188	319	8	x	x	PROPN
ctmj-188	319	9	,	,	PUNCT
ctmj-188	319	10	yu	yu	PROPN
ctmj-188	319	11	t	t	PROPN
ctmj-188	319	12	,	,	PUNCT
ctmj-188	319	13	zheng	zheng	PROPN
ctmj-188	319	14	x	x	PROPN
ctmj-188	319	15	,	,	PUNCT
ctmj-188	319	16	chu	chu	PROPN
ctmj-188	319	17	q.	q.	PROPN
ctmj-188	319	18	radix	radix	PROPN
ctmj-188	319	19	tetrastigma	tetrastigma	PROPN
ctmj-188	319	20	inhibits	inhibit	VERB
ctmj-188	319	21	the	the	DET
ctmj-188	319	22	non	non	ADJ
ctmj-188	319	23	-	-	ADJ
ctmj-188	319	24	small	small	ADJ
ctmj-188	319	25	cell	cell	NOUN
ctmj-188	319	26	lung	lung	NOUN
ctmj-188	319	27	cancer	cancer	NOUN
ctmj-188	319	28	via	via	ADP
ctmj-188	319	29	bax	bax	PROPN
ctmj-188	319	30	/	/	SYM
ctmj-188	319	31	bcl-2	bcl-2	NOUN
ctmj-188	319	32	/	/	SYM
ctmj-188	319	33	caspase-9	caspase-9	PROPN
ctmj-188	319	34	/	/	SYM
ctmj-188	319	35	caspase-3	caspase-3	NUM
ctmj-188	319	36	pathway	pathway	NOUN
ctmj-188	319	37	.	.	PUNCT
ctmj-188	320	1	nutr	nutr	NOUN
ctmj-188	320	2	cancer	cancer	NOUN
ctmj-188	320	3	2022;74:320‑32	2022;74:320‑32	NUM
ctmj-188	320	4	.	.	PROPN
ctmj-188	321	1	25	25	NUM
ctmj-188	321	2	.	.	PUNCT
ctmj-188	322	1	lamouille	lamouille	PROPN
ctmj-188	322	2	s	s	PROPN
ctmj-188	322	3	,	,	PUNCT
ctmj-188	322	4	xu	xu	PROPN
ctmj-188	322	5	j	j	PROPN
ctmj-188	322	6	,	,	PUNCT
ctmj-188	322	7	derynck	derynck	PROPN
ctmj-188	322	8	r.	r.	X
ctmj-188	322	9	molecular	molecular	ADJ
ctmj-188	322	10	mechanisms	mechanism	NOUN
ctmj-188	322	11	of	of	ADP
ctmj-188	322	12	epithelial‑mesenchymal	epithelial‑mesenchymal	ADJ
ctmj-188	322	13	transition	transition	NOUN
ctmj-188	322	14	.	.	PUNCT
ctmj-188	323	1	nat	nat	PROPN
ctmj-188	323	2	rev	rev	VERB
ctmj-188	323	3	mol	mol	ADP
ctmj-188	323	4	cell	cell	NOUN
ctmj-188	323	5	biol	biol	NOUN
ctmj-188	323	6	2014;15:178	2014;15:178	NOUN
ctmj-188	323	7	-	-	SYM
ctmj-188	323	8	96	96	NUM
ctmj-188	323	9	.	.	NOUN
ctmj-188	323	10	26	26	NUM
ctmj-188	323	11	.	.	PUNCT
ctmj-188	323	12	dongre	dongre	VERB
ctmj-188	323	13	a	a	PRON
ctmj-188	323	14	,	,	PUNCT
ctmj-188	323	15	weinberg	weinberg	PROPN
ctmj-188	323	16	ra	ra	PROPN
ctmj-188	323	17	.	.	PUNCT
ctmj-188	324	1	new	new	ADJ
ctmj-188	324	2	insights	insight	NOUN
ctmj-188	324	3	into	into	ADP
ctmj-188	324	4	the	the	DET
ctmj-188	324	5	mechanisms	mechanism	NOUN
ctmj-188	324	6	of	of	ADP
ctmj-188	324	7	epithelial‑mesenchymal	epithelial‑mesenchymal	ADJ
ctmj-188	324	8	transition	transition	NOUN
ctmj-188	324	9	and	and	CCONJ
ctmj-188	324	10	implications	implication	NOUN
ctmj-188	324	11	for	for	ADP
ctmj-188	324	12	cancer	cancer	NOUN
ctmj-188	324	13	.	.	PUNCT
ctmj-188	325	1	nat	nat	PROPN
ctmj-188	325	2	rev	rev	VERB
ctmj-188	325	3	mol	mol	ADP
ctmj-188	325	4	cell	cell	NOUN
ctmj-188	325	5	biol	biol	NOUN
ctmj-188	325	6	2019;20:69	2019;20:69	NUM
ctmj-188	325	7	-	-	PUNCT
ctmj-188	325	8	84	84	NUM
ctmj-188	325	9	.	.	PUNCT
ctmj-188	326	1	27	27	NUM
ctmj-188	326	2	.	.	PUNCT
ctmj-188	327	1	zhang	zhang	PROPN
ctmj-188	327	2	y	y	PROPN
ctmj-188	327	3	,	,	PUNCT
ctmj-188	327	4	weinberg	weinberg	PROPN
ctmj-188	327	5	ra	ra	PROPN
ctmj-188	327	6	.	.	PUNCT
ctmj-188	328	1	epithelial	epithelial	ADJ
ctmj-188	328	2	-	-	PUNCT
ctmj-188	328	3	to	to	ADP
ctmj-188	328	4	-	-	PUNCT
ctmj-188	328	5	mesenchymal	mesenchymal	ADJ
ctmj-188	328	6	transition	transition	NOUN
ctmj-188	328	7	in	in	ADP
ctmj-188	328	8	cancer	cancer	NOUN
ctmj-188	328	9	:	:	PUNCT
ctmj-188	328	10	complexity	complexity	NOUN
ctmj-188	328	11	and	and	CCONJ
ctmj-188	328	12	opportunities	opportunity	NOUN
ctmj-188	328	13	.	.	PUNCT
ctmj-188	329	1	front	front	ADJ
ctmj-188	329	2	med	med	ADJ
ctmj-188	329	3	2018;12:361	2018;12:361	PROPN
ctmj-188	329	4	-	-	SYM
ctmj-188	329	5	73	73	NUM
ctmj-188	329	6	.	.	PUNCT
ctmj-188	330	1	28	28	NUM
ctmj-188	330	2	.	.	PUNCT
ctmj-188	331	1	mittal	mittal	PROPN
ctmj-188	331	2	v.	v.	ADP
ctmj-188	331	3	epithelial	epithelial	ADJ
ctmj-188	331	4	mesenchymal	mesenchymal	NOUN
ctmj-188	331	5	transition	transition	NOUN
ctmj-188	331	6	in	in	ADP
ctmj-188	331	7	tumor	tumor	NOUN
ctmj-188	331	8	metastasis	metastasis	NOUN
ctmj-188	331	9	.	.	PUNCT
ctmj-188	332	1	annu	annu	PROPN
ctmj-188	332	2	rev	rev	PROPN
ctmj-188	332	3	pathol	pathol	PROPN
ctmj-188	332	4	2018;13:395‑412	2018;13:395‑412	PROPN
ctmj-188	332	5	.	.	PROPN
ctmj-188	332	6	29	29	NUM
ctmj-188	332	7	.	.	PUNCT
ctmj-188	333	1	van	van	PROPN
ctmj-188	333	2	roy	roy	PROPN
ctmj-188	333	3	f	f	PROPN
ctmj-188	333	4	,	,	PUNCT
ctmj-188	333	5	berx	berx	NOUN
ctmj-188	333	6	g.	g.	VERB
ctmj-188	333	7	the	the	DET
ctmj-188	333	8	cell‑cell	cell‑cell	PROPN
ctmj-188	333	9	adhesion	adhesion	NOUN
ctmj-188	333	10	molecule	molecule	NOUN
ctmj-188	333	11	e‑cadherin	e‑cadherin	PROPN
ctmj-188	333	12	.	.	PUNCT
ctmj-188	334	1	cell	cell	NOUN
ctmj-188	334	2	mol	mol	ADP
ctmj-188	334	3	life	life	NOUN
ctmj-188	334	4	sci	sci	PROPN
ctmj-188	334	5	2008;65:3756	2008;65:3756	PROPN
ctmj-188	334	6	-	-	SYM
ctmj-188	334	7	88	88	NUM
ctmj-188	334	8	.	.	PUNCT
ctmj-188	334	9	30	30	NUM
ctmj-188	334	10	.	.	PUNCT
ctmj-188	335	1	wong	wong	PROPN
ctmj-188	335	2	sh	sh	PROPN
ctmj-188	335	3	,	,	PUNCT
ctmj-188	335	4	fang	fang	PROPN
ctmj-188	335	5	cm	cm	PROPN
ctmj-188	335	6	,	,	PUNCT
ctmj-188	335	7	chuah	chuah	PROPN
ctmj-188	335	8	lh	lh	PROPN
ctmj-188	335	9	,	,	PUNCT
ctmj-188	335	10	leong	leong	PROPN
ctmj-188	335	11	co	co	PROPN
ctmj-188	335	12	,	,	PUNCT
ctmj-188	335	13	ngai	ngai	PROPN
ctmj-188	335	14	sc	sc	PROPN
ctmj-188	335	15	.	.	PUNCT
ctmj-188	336	1	e‑cadherin	e‑cadherin	PROPN
ctmj-188	336	2	:	:	PUNCT
ctmj-188	336	3	its	its	PRON
ctmj-188	336	4	dysregulation	dysregulation	NOUN
ctmj-188	336	5	in	in	ADP
ctmj-188	336	6	carcinogenesis	carcinogenesis	NOUN
ctmj-188	336	7	and	and	CCONJ
ctmj-188	336	8	clinical	clinical	ADJ
ctmj-188	336	9	implications	implication	NOUN
ctmj-188	336	10	.	.	PUNCT
ctmj-188	337	1	crit	crit	PROPN
ctmj-188	337	2	rev	rev	PROPN
ctmj-188	337	3	oncol	oncol	ADJ
ctmj-188	337	4	hematol	hematol	NOUN
ctmj-188	337	5	2018;121:11	2018;121:11	NUM
ctmj-188	337	6	-	-	SYM
ctmj-188	337	7	22	22	NUM
ctmj-188	337	8	.	.	PUNCT
ctmj-188	338	1	31	31	NUM
ctmj-188	338	2	.	.	PUNCT
ctmj-188	339	1	coopman	coopman	NOUN
ctmj-188	339	2	p	p	PROPN
ctmj-188	339	3	,	,	PUNCT
ctmj-188	339	4	djiane	djiane	PROPN
ctmj-188	339	5	a.	a.	NOUN
ctmj-188	339	6	adherens	adherens	PROPN
ctmj-188	339	7	junction	junction	PROPN
ctmj-188	339	8	and	and	CCONJ
ctmj-188	339	9	e‑cadherin	e‑cadherin	NOUN
ctmj-188	339	10	complex	complex	ADJ
ctmj-188	339	11	regulation	regulation	NOUN
ctmj-188	339	12	by	by	ADP
ctmj-188	339	13	epithelial	epithelial	ADJ
ctmj-188	339	14	polarity	polarity	NOUN
ctmj-188	339	15	.	.	PUNCT
ctmj-188	340	1	cell	cell	NOUN
ctmj-188	340	2	mol	mol	ADP
ctmj-188	340	3	life	life	NOUN
ctmj-188	340	4	sci	sci	PROPN
ctmj-188	340	5	2016;73:3535	2016;73:3535	PROPN
ctmj-188	340	6	-	-	SYM
ctmj-188	340	7	53	53	NUM
ctmj-188	340	8	.	.	PUNCT
ctmj-188	340	9	32	32	NUM
ctmj-188	340	10	.	.	PUNCT
ctmj-188	341	1	cao	cao	PROPN
ctmj-188	341	2	zq	zq	PROPN
ctmj-188	341	3	,	,	PUNCT
ctmj-188	341	4	wang	wang	PROPN
ctmj-188	341	5	z	z	PROPN
ctmj-188	341	6	,	,	PUNCT
ctmj-188	341	7	leng	leng	PROPN
ctmj-188	341	8	p.	p.	PROPN
ctmj-188	341	9	aberrant	aberrant	NOUN
ctmj-188	341	10	n‑cadherin	n‑cadherin	ADJ
ctmj-188	341	11	expression	expression	NOUN
ctmj-188	341	12	in	in	ADP
ctmj-188	341	13	cancer	cancer	NOUN
ctmj-188	341	14	.	.	PUNCT
ctmj-188	342	1	biomed	biome	VERB
ctmj-188	342	2	pharmacother	pharmacother	ADJ
ctmj-188	342	3	2019;118:109320	2019;118:109320	NUM
ctmj-188	342	4	.	.	PUNCT
ctmj-188	343	1	33	33	NUM
ctmj-188	343	2	.	.	PUNCT
ctmj-188	344	1	radice	radice	PROPN
ctmj-188	344	2	gl	gl	PROPN
ctmj-188	344	3	.	.	PUNCT
ctmj-188	345	1	n‑cadherin‑mediated	n‑cadherin‑mediate	VERB
ctmj-188	345	2	adhesion	adhesion	NOUN
ctmj-188	345	3	and	and	CCONJ
ctmj-188	345	4	signaling	signal	VERB
ctmj-188	345	5	from	from	ADP
ctmj-188	345	6	development	development	NOUN
ctmj-188	345	7	to	to	ADP
ctmj-188	345	8	disease	disease	NOUN
ctmj-188	345	9	:	:	PUNCT
ctmj-188	345	10	lessons	lesson	NOUN
ctmj-188	345	11	from	from	ADP
ctmj-188	345	12	mice	mouse	NOUN
ctmj-188	345	13	.	.	PUNCT
ctmj-188	346	1	prog	prog	NOUN
ctmj-188	346	2	mol	mol	ADP
ctmj-188	346	3	biol	biol	PROPN
ctmj-188	346	4	transl	transl	PROPN
ctmj-188	346	5	sci	sci	PROPN
ctmj-188	346	6	2013;116:263	2013;116:263	PROPN
ctmj-188	346	7	-	-	PROPN
ctmj-188	346	8	89	89	NUM
ctmj-188	346	9	.	.	PUNCT
ctmj-188	347	1	34	34	NUM
ctmj-188	347	2	.	.	PUNCT
ctmj-188	348	1	mariotti	mariotti	PROPN
ctmj-188	348	2	a	a	PRON
ctmj-188	348	3	,	,	PUNCT
ctmj-188	348	4	perotti	perotti	VERB
ctmj-188	348	5	a	a	PRON
ctmj-188	348	6	,	,	PUNCT
ctmj-188	348	7	sessa	sessa	ADJ
ctmj-188	348	8	c	c	NOUN
ctmj-188	348	9	,	,	PUNCT
ctmj-188	348	10	rüegg	rüegg	PROPN
ctmj-188	348	11	c.	c.	PROPN
ctmj-188	348	12	n‑cadherin	n‑cadherin	PROPN
ctmj-188	348	13	as	as	ADP
ctmj-188	348	14	a	a	DET
ctmj-188	348	15	therapeutic	therapeutic	ADJ
ctmj-188	348	16	target	target	NOUN
ctmj-188	348	17	in	in	ADP
ctmj-188	348	18	cancer	cancer	NOUN
ctmj-188	348	19	.	.	PUNCT
ctmj-188	349	1	expert	expert	NOUN
ctmj-188	349	2	opin	opin	NOUN
ctmj-188	349	3	investig	investig	NOUN
ctmj-188	349	4	drugs	drug	NOUN
ctmj-188	349	5	2007;16:451	2007;16:451	ADV
ctmj-188	349	6	-	-	SYM
ctmj-188	349	7	65	65	NUM
ctmj-188	349	8	.	.	NOUN
ctmj-188	349	9	35	35	NUM
ctmj-188	349	10	.	.	PUNCT
ctmj-188	350	1	satelli	satelli	PROPN
ctmj-188	350	2	a	a	PROPN
ctmj-188	350	3	,	,	PUNCT
ctmj-188	350	4	li	li	PROPN
ctmj-188	350	5	s.	s.	PROPN
ctmj-188	350	6	vimentin	vimentin	PROPN
ctmj-188	350	7	in	in	ADP
ctmj-188	350	8	cancer	cancer	NOUN
ctmj-188	350	9	and	and	CCONJ
ctmj-188	350	10	its	its	PRON
ctmj-188	350	11	potential	potential	NOUN
ctmj-188	350	12	as	as	ADP
ctmj-188	350	13	a	a	DET
ctmj-188	350	14	molecular	molecular	ADJ
ctmj-188	350	15	target	target	NOUN
ctmj-188	350	16	for	for	ADP
ctmj-188	350	17	cancer	cancer	NOUN
ctmj-188	350	18	therapy	therapy	NOUN
ctmj-188	350	19	.	.	PUNCT
ctmj-188	351	1	cell	cell	NOUN
ctmj-188	351	2	mol	mol	ADP
ctmj-188	351	3	life	life	NOUN
ctmj-188	351	4	sci	sci	PROPN
ctmj-188	351	5	2011;68:3033	2011;68:3033	PROPN
ctmj-188	351	6	-	-	SYM
ctmj-188	351	7	46	46	NUM
ctmj-188	351	8	.	.	PUNCT
ctmj-188	351	9	36	36	NUM
ctmj-188	351	10	.	.	PUNCT
ctmj-188	352	1	battaglia	battaglia	PROPN
ctmj-188	352	2	ra	ra	PROPN
ctmj-188	352	3	,	,	PUNCT
ctmj-188	352	4	delic	delic	PROPN
ctmj-188	352	5	s	s	PROPN
ctmj-188	352	6	,	,	PUNCT
ctmj-188	352	7	herrmann	herrmann	PROPN
ctmj-188	352	8	h	h	PROPN
ctmj-188	352	9	,	,	PUNCT
ctmj-188	352	10	snider	snider	PROPN
ctmj-188	352	11	nt	nt	PROPN
ctmj-188	352	12	.	.	PUNCT
ctmj-188	353	1	vimentin	vimentin	PROPN
ctmj-188	353	2	on	on	ADP
ctmj-188	353	3	the	the	DET
ctmj-188	353	4	move	move	NOUN
ctmj-188	353	5	:	:	PUNCT
ctmj-188	353	6	new	new	ADJ
ctmj-188	353	7	developments	development	NOUN
ctmj-188	353	8	in	in	ADP
ctmj-188	353	9	cell	cell	NOUN
ctmj-188	353	10	migration	migration	NOUN
ctmj-188	353	11	.	.	PUNCT
ctmj-188	354	1	f1000res	f1000res	PROPN
ctmj-188	354	2	2018;7	2018;7	NUM
ctmj-188	354	3	:	:	PUNCT
ctmj-188	354	4	v1000‑796	v1000‑796	PROPN
ctmj-188	354	5	.	.	PUNCT
ctmj-188	355	1	37	37	NUM
ctmj-188	355	2	.	.	X
ctmj-188	355	3	ramos	ramos	PROPN
ctmj-188	355	4	i	i	PROPN
ctmj-188	355	5	,	,	PUNCT
ctmj-188	355	6	stamatakis	stamatakis	PROPN
ctmj-188	355	7	k	k	NOUN
ctmj-188	355	8	,	,	PUNCT
ctmj-188	355	9	oeste	oeste	PROPN
ctmj-188	355	10	cl	cl	PROPN
ctmj-188	355	11	,	,	PUNCT
ctmj-188	355	12	pérez‑sala	pérez‑sala	PROPN
ctmj-188	355	13	d.	d.	PROPN
ctmj-188	355	14	vimentin	vimentin	PROPN
ctmj-188	355	15	as	as	ADP
ctmj-188	355	16	a	a	DET
ctmj-188	355	17	multifaceted	multifaceted	ADJ
ctmj-188	355	18	player	player	NOUN
ctmj-188	355	19	and	and	CCONJ
ctmj-188	355	20	potential	potential	ADJ
ctmj-188	355	21	therapeutic	therapeutic	ADJ
ctmj-188	355	22	target	target	NOUN
ctmj-188	355	23	in	in	ADP
ctmj-188	355	24	viral	viral	ADJ
ctmj-188	355	25	infections	infection	NOUN
ctmj-188	355	26	.	.	PUNCT
ctmj-188	356	1	int	int	PROPN
ctmj-188	356	2	j	j	PROPN
ctmj-188	356	3	mol	mol	ADP
ctmj-188	356	4	sci	sci	PROPN
ctmj-188	356	5	2020;21:4675	2020;21:4675	PROPN
ctmj-188	356	6	.	.	PROPN
ctmj-188	357	1	38	38	NUM
ctmj-188	357	2	.	.	PUNCT
ctmj-188	358	1	omura	omura	PROPN
ctmj-188	358	2	k.	k.	PROPN
ctmj-188	358	3	clinical	clinical	ADJ
ctmj-188	358	4	implications	implication	NOUN
ctmj-188	358	5	of	of	ADP
ctmj-188	358	6	dihydropyrimidine	dihydropyrimidine	ADJ
ctmj-188	358	7	dehydrogenase	dehydrogenase	NOUN
ctmj-188	358	8	(	(	PUNCT
ctmj-188	358	9	dpd	dpd	NOUN
ctmj-188	358	10	)	)	PUNCT
ctmj-188	358	11	activity	activity	NOUN
ctmj-188	358	12	in	in	ADP
ctmj-188	358	13	5‑fu‑based	5‑fu‑based	NUM
ctmj-188	358	14	chemotherapy	chemotherapy	NOUN
ctmj-188	358	15	:	:	PUNCT
ctmj-188	358	16	mutations	mutation	NOUN
ctmj-188	358	17	in	in	ADP
ctmj-188	358	18	the	the	DET
ctmj-188	358	19	dpd	dpd	PROPN
ctmj-188	358	20	gene	gene	NOUN
ctmj-188	358	21	,	,	PUNCT
ctmj-188	358	22	and	and	CCONJ
ctmj-188	358	23	dpd	dpd	PROPN
ctmj-188	358	24	inhibitory	inhibitory	ADJ
ctmj-188	358	25	fluoropyrimidines	fluoropyrimidine	NOUN
ctmj-188	358	26	.	.	PUNCT
ctmj-188	359	1	int	int	PROPN
ctmj-188	360	1	j	j	PROPN
ctmj-188	360	2	clin	clin	PROPN
ctmj-188	360	3	oncol	oncol	PROPN
ctmj-188	360	4	2003;8:132	2003;8:132	PROPN
ctmj-188	360	5	-	-	SYM
ctmj-188	360	6	8	8	NUM
ctmj-188	360	7	.	.	NOUN
ctmj-188	360	8	39	39	NUM
ctmj-188	360	9	.	.	PUNCT
ctmj-188	361	1	xie	xie	PROPN
ctmj-188	361	2	p	p	PROPN
ctmj-188	361	3	,	,	PUNCT
ctmj-188	361	4	mo	mo	PROPN
ctmj-188	361	5	jl	jl	PROPN
ctmj-188	361	6	,	,	PUNCT
ctmj-188	361	7	liu	liu	PROPN
ctmj-188	361	8	jh	jh	PROPN
ctmj-188	361	9	,	,	PUNCT
ctmj-188	361	10	li	li	PROPN
ctmj-188	361	11	x	x	PROPN
ctmj-188	361	12	,	,	PUNCT
ctmj-188	361	13	tan	tan	PROPN
ctmj-188	361	14	lm	lm	PROPN
ctmj-188	361	15	,	,	PUNCT
ctmj-188	361	16	zhang	zhang	PROPN
ctmj-188	361	17	w	w	PROPN
ctmj-188	361	18	,	,	PUNCT
ctmj-188	361	19	et	et	PROPN
ctmj-188	361	20	al	al	PROPN
ctmj-188	361	21	.	.	PROPN
ctmj-188	361	22	pharmacogenomics	pharmacogenomics	PROPN
ctmj-188	361	23	57	57	NUM
ctmj-188	361	24	ctmj	ctmj	NOUN
ctmj-188	362	1	|	|	ADV
ctmj-188	362	2	traditionalmedicinejournals.com	traditionalmedicinejournals.com	X
ctmj-188	362	3	chinese	chinese	ADJ
ctmj-188	362	4	traditional	traditional	ADJ
ctmj-188	362	5	medicine	medicine	NOUN
ctmj-188	362	6	journal	journal	NOUN
ctmj-188	362	7	|	|	ADV
ctmj-188	362	8	2025	2025	NUM
ctmj-188	362	9	|	|	ADV
ctmj-188	362	10	vol	vol	NOUN
ctmj-188	362	11	8	8	NUM
ctmj-188	362	12	|issue	|issue	NOUN
ctmj-188	362	13	1	1	NUM
ctmj-188	362	14	57	57	NUM
ctmj-188	362	15	of	of	ADP
ctmj-188	362	16	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	362	17	in	in	ADP
ctmj-188	362	18	colorectal	colorectal	ADJ
ctmj-188	362	19	cancer	cancer	NOUN
ctmj-188	362	20	:	:	PUNCT
ctmj-188	362	21	review	review	NOUN
ctmj-188	362	22	and	and	CCONJ
ctmj-188	362	23	update	update	VERB
ctmj-188	362	24	.	.	PUNCT
ctmj-188	363	1	cell	cell	NOUN
ctmj-188	363	2	oncol	oncol	ADJ
ctmj-188	363	3	(	(	PUNCT
ctmj-188	363	4	dordr	dordr	ADV
ctmj-188	363	5	)	)	PUNCT
ctmj-188	363	6	2020;43:989	2020;43:989	PROPN
ctmj-188	363	7	-	-	SYM
ctmj-188	363	8	1001	1001	NUM
ctmj-188	363	9	.	.	PUNCT
ctmj-188	364	1	40	40	NUM
ctmj-188	364	2	.	.	PUNCT
ctmj-188	365	1	akhter	akhter	PROPN
ctmj-188	365	2	k	k	PROPN
ctmj-188	365	3	,	,	PUNCT
ctmj-188	365	4	enamur	enamur	ADJ
ctmj-188	365	5	rashid	rashid	PROPN
ctmj-188	365	6	m.	m.	PROPN
ctmj-188	365	7	study	study	NOUN
ctmj-188	365	8	of	of	ADP
ctmj-188	365	9	thymidylate	thymidylate	ADJ
ctmj-188	365	10	synthase	synthase	NOUN
ctmj-188	365	11	(	(	PUNCT
ctmj-188	365	12	ts	ts	NOUN
ctmj-188	365	13	)	)	PUNCT
ctmj-188	365	14	and	and	CCONJ
ctmj-188	365	15	dihydropyrimidine	dihydropyrimidine	ADJ
ctmj-188	365	16	dehydrogenase	dehydrogenase	NOUN
ctmj-188	365	17	(	(	PUNCT
ctmj-188	365	18	dpd	dpd	NOUN
ctmj-188	365	19	)	)	PUNCT
ctmj-188	365	20	expressions	expression	NOUN
ctmj-188	365	21	on	on	ADP
ctmj-188	365	22	5‑fluorouracil	5‑fluorouracil	NUM
ctmj-188	365	23	in	in	ADP
ctmj-188	365	24	oral	oral	ADJ
ctmj-188	365	25	squamous	squamous	ADJ
ctmj-188	365	26	cell	cell	NOUN
ctmj-188	365	27	carcinoma	carcinoma	NOUN
ctmj-188	365	28	.	.	PUNCT
ctmj-188	366	1	asian	asian	PROPN
ctmj-188	366	2	pac	pac	PROPN
ctmj-188	366	3	j	j	PROPN
ctmj-188	366	4	cancer	cancer	PROPN
ctmj-188	366	5	prev	prev	X
ctmj-188	366	6	2019;20:503‑8	2019;20:503‑8	NUM
ctmj-188	366	7	.	.	PUNCT
ctmj-188	366	8	41	41	NUM
ctmj-188	366	9	.	.	PUNCT
ctmj-188	367	1	fan	fan	PROPN
ctmj-188	367	2	j	j	PROPN
ctmj-188	367	3	,	,	PUNCT
ctmj-188	367	4	bao	bao	PROPN
ctmj-188	367	5	y	y	PROPN
ctmj-188	367	6	,	,	PUNCT
ctmj-188	367	7	meng	meng	PROPN
ctmj-188	367	8	x	x	PROPN
ctmj-188	367	9	,	,	PUNCT
ctmj-188	367	10	wang	wang	PROPN
ctmj-188	367	11	s	s	PROPN
ctmj-188	367	12	,	,	PUNCT
ctmj-188	367	13	li	li	PROPN
ctmj-188	367	14	t	t	PROPN
ctmj-188	367	15	,	,	PUNCT
ctmj-188	367	16	chang	chang	PROPN
ctmj-188	367	17	x	x	PROPN
ctmj-188	367	18	,	,	PUNCT
ctmj-188	367	19	et	et	PROPN
ctmj-188	367	20	al	al	PROPN
ctmj-188	367	21	.	.	PUNCT
ctmj-188	367	22	mechanism	mechanism	NOUN
ctmj-188	367	23	of	of	ADP
ctmj-188	367	24	modulation	modulation	NOUN
ctmj-188	367	25	through	through	ADP
ctmj-188	367	26	pi3k‑akt	pi3k‑akt	PROPN
ctmj-188	367	27	pathway	pathway	NOUN
ctmj-188	367	28	about	about	ADP
ctmj-188	367	29	nepeta	nepeta	PROPN
ctmj-188	367	30	cataria	cataria	PROPN
ctmj-188	367	31	l.	l.	PROPN
ctmj-188	367	32	’s	’s	PART
ctmj-188	367	33	extract	extract	NOUN
ctmj-188	367	34	in	in	ADP
ctmj-188	367	35	non	non	ADJ
ctmj-188	367	36	-	-	ADJ
ctmj-188	367	37	small	small	ADJ
ctmj-188	367	38	cell	cell	NOUN
ctmj-188	367	39	lung	lung	NOUN
ctmj-188	367	40	cancer	cancer	NOUN
ctmj-188	367	41	.	.	PUNCT
ctmj-188	368	1	oncotarget	oncotarget	PROPN
ctmj-188	368	2	2017;8:31395	2017;8:31395	PROPN
ctmj-188	368	3	-	-	SYM
ctmj-188	368	4	405	405	NUM
ctmj-188	368	5	.	.	PUNCT
ctmj-188	369	1	42	42	NUM
ctmj-188	369	2	.	.	PUNCT
ctmj-188	370	1	chen	chen	PROPN
ctmj-188	370	2	h	h	PROPN
ctmj-188	370	3	,	,	PUNCT
ctmj-188	370	4	zhou	zhou	PROPN
ctmj-188	370	5	l	l	PROPN
ctmj-188	370	6	,	,	PUNCT
ctmj-188	370	7	wu	wu	PROPN
ctmj-188	370	8	x	x	PROPN
ctmj-188	370	9	,	,	PUNCT
ctmj-188	370	10	li	li	PROPN
ctmj-188	370	11	r	r	PROPN
ctmj-188	370	12	,	,	PUNCT
ctmj-188	370	13	wen	wen	PROPN
ctmj-188	370	14	j	j	PROPN
ctmj-188	370	15	,	,	PUNCT
ctmj-188	370	16	sha	sha	PROPN
ctmj-188	370	17	j	j	PROPN
ctmj-188	370	18	,	,	PUNCT
ctmj-188	370	19	et	et	PROPN
ctmj-188	370	20	al	al	PROPN
ctmj-188	370	21	.	.	PUNCT
ctmj-188	371	1	the	the	DET
ctmj-188	371	2	pi3k	pi3k	PROPN
ctmj-188	371	3	/	/	SYM
ctmj-188	371	4	akt	akt	PROPN
ctmj-188	371	5	pathway	pathway	NOUN
ctmj-188	371	6	in	in	ADP
ctmj-188	371	7	the	the	DET
ctmj-188	371	8	pathogenesis	pathogenesis	NOUN
ctmj-188	371	9	of	of	ADP
ctmj-188	371	10	prostate	prostate	NOUN
ctmj-188	371	11	cancer	cancer	NOUN
ctmj-188	371	12	.	.	PUNCT
ctmj-188	372	1	front	front	ADJ
ctmj-188	372	2	biosci	biosci	PROPN
ctmj-188	372	3	(	(	PUNCT
ctmj-188	372	4	landmark	landmark	PROPN
ctmj-188	372	5	ed	ed	NOUN
ctmj-188	372	6	)	)	PUNCT
ctmj-188	372	7	2016;21:1084	2016;21:1084	NUM
ctmj-188	372	8	-	-	SYM
ctmj-188	372	9	91	91	NUM
ctmj-188	372	10	.	.	PUNCT
ctmj-188	373	1	43	43	NUM
ctmj-188	373	2	.	.	PUNCT
ctmj-188	374	1	chen	chen	PROPN
ctmj-188	374	2	yh	yh	PROPN
ctmj-188	374	3	,	,	PUNCT
ctmj-188	374	4	yang	yang	PROPN
ctmj-188	374	5	sf	sf	PROPN
ctmj-188	374	6	,	,	PUNCT
ctmj-188	374	7	yang	yang	PROPN
ctmj-188	374	8	ck	ck	PROPN
ctmj-188	374	9	,	,	PUNCT
ctmj-188	374	10	tsai	tsai	PROPN
ctmj-188	374	11	hd	hd	PROPN
ctmj-188	374	12	,	,	PUNCT
ctmj-188	374	13	chen	chen	PROPN
ctmj-188	374	14	th	th	PROPN
ctmj-188	374	15	,	,	PUNCT
ctmj-188	374	16	chou	chou	PROPN
ctmj-188	374	17	mc	mc	PROPN
ctmj-188	374	18	,	,	PUNCT
ctmj-188	374	19	et	et	PROPN
ctmj-188	374	20	al	al	PROPN
ctmj-188	374	21	.	.	PUNCT
ctmj-188	375	1	metformin	metformin	PROPN
ctmj-188	375	2	induces	induce	VERB
ctmj-188	375	3	apoptosis	apoptosis	NOUN
ctmj-188	375	4	and	and	CCONJ
ctmj-188	375	5	inhibits	inhibit	VERB
ctmj-188	375	6	migration	migration	NOUN
ctmj-188	375	7	by	by	ADP
ctmj-188	375	8	activating	activate	VERB
ctmj-188	375	9	the	the	DET
ctmj-188	375	10	ampk	ampk	NOUN
ctmj-188	375	11	/	/	SYM
ctmj-188	375	12	p53	p53	NOUN
ctmj-188	375	13	axis	axis	NOUN
ctmj-188	375	14	and	and	CCONJ
ctmj-188	375	15	suppressing	suppress	VERB
ctmj-188	375	16	pi3k	pi3k	PROPN
ctmj-188	375	17	/	/	SYM
ctmj-188	375	18	akt	akt	PROPN
ctmj-188	375	19	signaling	signal	VERB
ctmj-188	375	20	in	in	ADP
ctmj-188	375	21	human	human	ADJ
ctmj-188	375	22	cervical	cervical	ADJ
ctmj-188	375	23	cancer	cancer	NOUN
ctmj-188	375	24	cells	cell	NOUN
ctmj-188	375	25	.	.	PUNCT
ctmj-188	376	1	mol	mol	ADP
ctmj-188	376	2	med	med	PROPN
ctmj-188	376	3	rep	rep	PROPN
ctmj-188	376	4	2021;23:88	2021;23:88	PROPN
ctmj-188	376	5	.	.	PUNCT
ctmj-188	377	1	44	44	NUM
ctmj-188	377	2	.	.	PUNCT
ctmj-188	378	1	wang	wang	PROPN
ctmj-188	378	2	r	r	PROPN
ctmj-188	378	3	,	,	PUNCT
ctmj-188	378	4	song	song	NOUN
ctmj-188	378	5	f	f	PROPN
ctmj-188	378	6	,	,	PUNCT
ctmj-188	378	7	li	li	PROPN
ctmj-188	378	8	s	s	PROPN
ctmj-188	378	9	,	,	PUNCT
ctmj-188	378	10	wu	wu	PROPN
ctmj-188	378	11	b	b	PROPN
ctmj-188	378	12	,	,	PUNCT
ctmj-188	378	13	gu	gu	NOUN
ctmj-188	378	14	y	y	PROPN
ctmj-188	378	15	,	,	PUNCT
ctmj-188	378	16	yuan	yuan	PROPN
ctmj-188	378	17	y.	y.	PROPN
ctmj-188	378	18	salvianolic	salvianolic	PROPN
ctmj-188	378	19	acid	acid	PROPN
ctmj-188	378	20	a	a	DET
ctmj-188	378	21	attenuates	attenuate	NOUN
ctmj-188	378	22	ccl(4)‑induced	ccl(4)‑induce	VERB
ctmj-188	378	23	liver	liver	NOUN
ctmj-188	378	24	fibrosis	fibrosis	NOUN
ctmj-188	378	25	by	by	ADP
ctmj-188	378	26	regulating	regulate	VERB
ctmj-188	378	27	the	the	DET
ctmj-188	378	28	pi3k	pi3k	PROPN
ctmj-188	378	29	/	/	SYM
ctmj-188	378	30	akt	akt	PROPN
ctmj-188	378	31	/	/	SYM
ctmj-188	378	32	mtor	mtor	PROPN
ctmj-188	378	33	,	,	PUNCT
ctmj-188	378	34	bcl-2	bcl-2	NOUN
ctmj-188	378	35	/	/	SYM
ctmj-188	378	36	bax	bax	PROPN
ctmj-188	378	37	and	and	CCONJ
ctmj-188	378	38	caspase-3	caspase-3	PROPN
ctmj-188	378	39	/	/	SYM
ctmj-188	378	40	cleaved	cleaved	ADJ
ctmj-188	378	41	caspase-3	caspase-3	PUNCT
ctmj-188	378	42	signaling	signal	VERB
ctmj-188	378	43	pathways	pathway	NOUN
ctmj-188	378	44	.	.	PUNCT
ctmj-188	379	1	drug	drug	NOUN
ctmj-188	379	2	des	des	PROPN
ctmj-188	379	3	devel	devel	NOUN
ctmj-188	379	4	ther	ther	VERB
ctmj-188	379	5	2019;13:1889	2019;13:1889	NUM
ctmj-188	379	6	-	-	SYM
ctmj-188	379	7	900	900	NUM
ctmj-188	379	8	.	.	PUNCT
ctmj-188	380	1	45	45	NUM
ctmj-188	380	2	.	.	PUNCT
ctmj-188	381	1	ha	ha	INTJ
ctmj-188	381	2	se	se	PROPN
ctmj-188	381	3	,	,	PUNCT
ctmj-188	381	4	kim	kim	PROPN
ctmj-188	381	5	sm	sm	PROPN
ctmj-188	381	6	,	,	PUNCT
ctmj-188	381	7	vetrivel	vetrivel	VERB
ctmj-188	381	8	p	p	X
ctmj-188	381	9	,	,	PUNCT
ctmj-188	381	10	kim	kim	PROPN
ctmj-188	381	11	hh	hh	PROPN
ctmj-188	381	12	,	,	PUNCT
ctmj-188	381	13	bhosale	bhosale	NOUN
ctmj-188	381	14	pb	pb	ADP
ctmj-188	381	15	,	,	PUNCT
ctmj-188	381	16	heo	heo	PROPN
ctmj-188	381	17	jd	jd	PROPN
ctmj-188	381	18	,	,	PUNCT
ctmj-188	381	19	et	et	PROPN
ctmj-188	381	20	al	al	PROPN
ctmj-188	381	21	.	.	PROPN
ctmj-188	382	1	inhibition	inhibition	NOUN
ctmj-188	382	2	of	of	ADP
ctmj-188	382	3	cell	cell	NOUN
ctmj-188	382	4	proliferation	proliferation	NOUN
ctmj-188	382	5	and	and	CCONJ
ctmj-188	382	6	metastasis	metastasis	NOUN
ctmj-188	382	7	by	by	ADP
ctmj-188	382	8	scutellarein	scutellarein	ADV
ctmj-188	382	9	regulating	regulate	VERB
ctmj-188	382	10	pi3k	pi3k	PROPN
ctmj-188	382	11	/	/	SYM
ctmj-188	382	12	akt	akt	PROPN
ctmj-188	382	13	/	/	SYM
ctmj-188	382	14	nf‑κb	nf‑κb	PROPN
ctmj-188	382	15	signaling	signal	VERB
ctmj-188	382	16	through	through	ADP
ctmj-188	382	17	pten	pten	ADJ
ctmj-188	382	18	activation	activation	NOUN
ctmj-188	382	19	in	in	ADP
ctmj-188	382	20	hepatocellular	hepatocellular	ADJ
ctmj-188	382	21	carcinoma	carcinoma	NOUN
ctmj-188	382	22	.	.	PUNCT
ctmj-188	383	1	int	int	PROPN
ctmj-188	383	2	j	j	PROPN
ctmj-188	383	3	mol	mol	ADP
ctmj-188	383	4	sci	sci	PROPN
ctmj-188	383	5	2021;22:8841	2021;22:8841	PROPN
ctmj-188	383	6	.	.	PUNCT