id	sid	tid	token	lemma	pos
cuesj-1234	1	1	tx_1	tx_1	PROPN
cuesj-1234	1	2	~	~	X
cuesj-1234	1	3	abs	ab	NOUN
cuesj-1234	1	4	:	:	PUNCT
cuesj-1234	1	5	at	at	ADP
cuesj-1234	1	6	/	/	SYM
cuesj-1234	1	7	add	add	VERB
cuesj-1234	1	8	:	:	PUNCT
cuesj-1234	1	9	tx_2	tx_2	PROPN
cuesj-1234	1	10	~	~	NOUN
cuesj-1234	1	11	abs	ab	NOUN
cuesj-1234	1	12	:	:	PUNCT
cuesj-1234	1	13	at	at	ADP
cuesj-1234	1	14	26	26	NUM
cuesj-1234	1	15	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	1	16	cuesj	cuesj	NOUN
cuesj-1234	1	17	2025	2025	NUM
cuesj-1234	1	18	,	,	PUNCT
cuesj-1234	1	19	9	9	NUM
cuesj-1234	1	20	(	(	PUNCT
cuesj-1234	1	21	2	2	NUM
cuesj-1234	1	22	):	):	PUNCT
cuesj-1234	1	23	26	26	NUM
cuesj-1234	1	24	-	-	SYM
cuesj-1234	1	25	32	32	NUM
cuesj-1234	1	26	research	research	NOUN
cuesj-1234	1	27	article	article	NOUN
cuesj-1234	1	28	enhancement	enhancement	NOUN
cuesj-1234	1	29	of	of	ADP
cuesj-1234	1	30	the	the	DET
cuesj-1234	1	31	solubility	solubility	NOUN
cuesj-1234	1	32	of	of	ADP
cuesj-1234	1	33	simvastatin	simvastatin	NOUN
cuesj-1234	1	34	by	by	ADP
cuesj-1234	1	35	utilizing	utilize	VERB
cuesj-1234	1	36	two	two	NUM
cuesj-1234	1	37	distinct	distinct	ADJ
cuesj-1234	1	38	types	type	NOUN
cuesj-1234	1	39	of	of	ADP
cuesj-1234	1	40	excipient	excipient	ADJ
cuesj-1234	1	41	compositions	composition	NOUN
cuesj-1234	1	42	,	,	PUNCT
cuesj-1234	1	43	l	l	NOUN
cuesj-1234	1	44	-	-	NOUN
cuesj-1234	1	45	isoleucine	isoleucine	ADJ
cuesj-1234	1	46	and	and	CCONJ
cuesj-1234	1	47	sodium	sodium	NOUN
cuesj-1234	1	48	docusate	docusate	NOUN
cuesj-1234	1	49	maysra	maysra	PROPN
cuesj-1234	1	50	a.	a.	PROPN
cuesj-1234	1	51	al	al	PROPN
cuesj-1234	1	52	-	-	PUNCT
cuesj-1234	1	53	jumaili1	jumaili1	PROPN
cuesj-1234	1	54	,	,	PUNCT
cuesj-1234	1	55	suzan	suzan	PROPN
cuesj-1234	1	56	n.	n.	PROPN
cuesj-1234	1	57	alamdar2	alamdar2	PROPN
cuesj-1234	1	58	,	,	PUNCT
cuesj-1234	1	59	marwa	marwa	PROPN
cuesj-1234	1	60	f.	f.	PROPN
cuesj-1234	1	61	noori3	noori3	PROPN
cuesj-1234	1	62	,	,	PUNCT
cuesj-1234	1	63	hewa	hewa	PROPN
cuesj-1234	1	64	a.	a.	PROPN
cuesj-1234	1	65	hamad	hamad	PROPN
cuesj-1234	2	1	ameen1	ameen1	PROPN
cuesj-1234	2	2	,	,	PUNCT
cuesj-1234	2	3	muhamed	muhamed	PROPN
cuesj-1234	2	4	a.	a.	PROPN
cuesj-1234	2	5	abbas3	abbas3	PROPN
cuesj-1234	2	6	1department	1department	NUM
cuesj-1234	2	7	of	of	ADP
cuesj-1234	2	8	pharmaceutics	pharmaceutic	NOUN
cuesj-1234	2	9	,	,	PUNCT
cuesj-1234	2	10	college	college	NOUN
cuesj-1234	2	11	of	of	ADP
cuesj-1234	2	12	pharmacy	pharmacy	NOUN
cuesj-1234	2	13	,	,	PUNCT
cuesj-1234	2	14	hawler	hawler	PROPN
cuesj-1234	2	15	medical	medical	PROPN
cuesj-1234	2	16	university	university	PROPN
cuesj-1234	2	17	,	,	PUNCT
cuesj-1234	2	18	erbil	erbil	PROPN
cuesj-1234	2	19	,	,	PUNCT
cuesj-1234	2	20	iraq	iraq	PROPN
cuesj-1234	2	21	,	,	PUNCT
cuesj-1234	2	22	2department	2department	NUM
cuesj-1234	2	23	of	of	ADP
cuesj-1234	2	24	clinical	clinical	ADJ
cuesj-1234	2	25	pharmacy	pharmacy	NOUN
cuesj-1234	2	26	,	,	PUNCT
cuesj-1234	2	27	raparin	raparin	NOUN
cuesj-1234	2	28	teaching	teaching	NOUN
cuesj-1234	2	29	hospital	hospital	NOUN
cuesj-1234	2	30	,	,	PUNCT
cuesj-1234	2	31	erbil	erbil	PROPN
cuesj-1234	2	32	,	,	PUNCT
cuesj-1234	2	33	iraq	iraq	PROPN
cuesj-1234	2	34	,	,	PUNCT
cuesj-1234	2	35	3college	3college	PROPN
cuesj-1234	2	36	of	of	ADP
cuesj-1234	2	37	pharmacy	pharmacy	NOUN
cuesj-1234	2	38	,	,	PUNCT
cuesj-1234	2	39	cihan	cihan	VERB
cuesj-1234	2	40	university	university	NOUN
cuesj-1234	2	41	-	-	PUNCT
cuesj-1234	2	42	erbil	erbil	PROPN
cuesj-1234	2	43	,	,	PUNCT
cuesj-1234	2	44	kurdistan	kurdistan	ADJ
cuesj-1234	2	45	region	region	NOUN
cuesj-1234	2	46	,	,	PUNCT
cuesj-1234	2	47	iraq	iraq	PROPN
cuesj-1234	2	48	abstract	abstract	VERB
cuesj-1234	2	49	the	the	DET
cuesj-1234	2	50	solubility	solubility	NOUN
cuesj-1234	2	51	of	of	ADP
cuesj-1234	2	52	a	a	DET
cuesj-1234	2	53	drug	drug	NOUN
cuesj-1234	2	54	plays	play	VERB
cuesj-1234	2	55	an	an	DET
cuesj-1234	2	56	important	important	ADJ
cuesj-1234	2	57	role	role	NOUN
cuesj-1234	2	58	in	in	ADP
cuesj-1234	2	59	determining	determine	VERB
cuesj-1234	2	60	its	its	PRON
cuesj-1234	2	61	bioavailability	bioavailability	NOUN
cuesj-1234	2	62	and	and	CCONJ
cuesj-1234	2	63	the	the	DET
cuesj-1234	2	64	subsequent	subsequent	ADJ
cuesj-1234	2	65	effect	effect	NOUN
cuesj-1234	2	66	it	it	PRON
cuesj-1234	2	67	has	have	VERB
cuesj-1234	2	68	on	on	ADP
cuesj-1234	2	69	the	the	DET
cuesj-1234	2	70	body	body	NOUN
cuesj-1234	2	71	as	as	ADP
cuesj-1234	2	72	a	a	DET
cuesj-1234	2	73	whole	whole	NOUN
cuesj-1234	2	74	.	.	PUNCT
cuesj-1234	3	1	simvastatin	simvastatin	PROPN
cuesj-1234	3	2	is	be	AUX
cuesj-1234	3	3	a	a	DET
cuesj-1234	3	4	bcs	bcs	NOUN
cuesj-1234	3	5	class	class	NOUN
cuesj-1234	3	6	 	 	SPACE
cuesj-1234	3	7	ii	ii	PROPN
cuesj-1234	3	8	drug	drug	NOUN
cuesj-1234	3	9	,	,	PUNCT
cuesj-1234	3	10	classified	classify	VERB
cuesj-1234	3	11	as	as	ADP
cuesj-1234	3	12	having	have	VERB
cuesj-1234	3	13	high	high	ADJ
cuesj-1234	3	14	absorbability	absorbability	NOUN
cuesj-1234	3	15	but	but	CCONJ
cuesj-1234	3	16	low	low	ADJ
cuesj-1234	3	17	solubility	solubility	NOUN
cuesj-1234	3	18	.	.	PUNCT
cuesj-1234	4	1	the	the	DET
cuesj-1234	4	2	study	study	NOUN
cuesj-1234	4	3	objective	objective	NOUN
cuesj-1234	4	4	is	be	AUX
cuesj-1234	4	5	to	to	PART
cuesj-1234	4	6	increase	increase	VERB
cuesj-1234	4	7	the	the	DET
cuesj-1234	4	8	solubility	solubility	NOUN
cuesj-1234	4	9	of	of	ADP
cuesj-1234	4	10	simvastatin	simvastatin	NOUN
cuesj-1234	4	11	by	by	ADP
cuesj-1234	4	12	using	use	VERB
cuesj-1234	4	13	two	two	NUM
cuesj-1234	4	14	excipients	excipient	NOUN
cuesj-1234	4	15	:	:	PUNCT
cuesj-1234	4	16	sodium	sodium	NOUN
cuesj-1234	4	17	docusate	docusate	NOUN
cuesj-1234	4	18	and	and	CCONJ
cuesj-1234	4	19	l	l	NOUN
cuesj-1234	4	20	-	-	NOUN
cuesj-1234	4	21	isoleucine	isoleucine	NOUN
cuesj-1234	4	22	.	.	PUNCT
cuesj-1234	5	1	these	these	DET
cuesj-1234	5	2	excipients	excipient	NOUN
cuesj-1234	5	3	were	be	AUX
cuesj-1234	5	4	incorporated	incorporate	VERB
cuesj-1234	5	5	in	in	ADP
cuesj-1234	5	6	a	a	DET
cuesj-1234	5	7	solid	solid	ADJ
cuesj-1234	5	8	dispersion	dispersion	NOUN
cuesj-1234	5	9	at	at	ADP
cuesj-1234	5	10	different	different	ADJ
cuesj-1234	5	11	ratios	ratio	NOUN
cuesj-1234	5	12	,	,	PUNCT
cuesj-1234	5	13	left	leave	VERB
cuesj-1234	5	14	to	to	ADP
cuesj-1234	5	15	dry	dry	ADJ
cuesj-1234	5	16	,	,	PUNCT
cuesj-1234	5	17	dissolved	dissolve	VERB
cuesj-1234	5	18	,	,	PUNCT
cuesj-1234	5	19	and	and	CCONJ
cuesj-1234	5	20	tested	test	VERB
cuesj-1234	5	21	for	for	ADP
cuesj-1234	5	22	increased	increase	VERB
cuesj-1234	5	23	solubility	solubility	NOUN
cuesj-1234	5	24	against	against	ADP
cuesj-1234	5	25	a	a	DET
cuesj-1234	5	26	simvastatin	simvastatin	ADJ
cuesj-1234	5	27	calibration	calibration	NOUN
cuesj-1234	5	28	curve	curve	NOUN
cuesj-1234	5	29	(	(	PUNCT
cuesj-1234	5	30	which	which	PRON
cuesj-1234	5	31	was	be	AUX
cuesj-1234	5	32	prepared	prepare	VERB
cuesj-1234	5	33	using	use	VERB
cuesj-1234	5	34	a	a	DET
cuesj-1234	5	35	standard	standard	ADJ
cuesj-1234	5	36	solution	solution	NOUN
cuesj-1234	5	37	of	of	ADP
cuesj-1234	5	38	simvastatin	simvastatin	NOUN
cuesj-1234	5	39	)	)	PUNCT
cuesj-1234	5	40	.	.	PUNCT
cuesj-1234	6	1	the	the	DET
cuesj-1234	6	2	improvement	improvement	NOUN
cuesj-1234	6	3	in	in	ADP
cuesj-1234	6	4	solubility	solubility	NOUN
cuesj-1234	6	5	for	for	ADP
cuesj-1234	6	6	a	a	DET
cuesj-1234	6	7	4:1:1	4:1:1	PROPN
cuesj-1234	6	8	ratio	ratio	NOUN
cuesj-1234	6	9	was	be	AUX
cuesj-1234	6	10	approximately	approximately	ADV
cuesj-1234	6	11	1.5	1.5	NUM
cuesj-1234	6	12	-	-	NUM
cuesj-1234	6	13	fold	fold	ADJ
cuesj-1234	6	14	.	.	PUNCT
cuesj-1234	7	1	a	a	DET
cuesj-1234	7	2	 	 	SPACE
cuesj-1234	7	3	2:1:1	2:1:1	NUM
cuesj-1234	7	4	ratio	ratio	NOUN
cuesj-1234	7	5	of	of	ADP
cuesj-1234	7	6	simvastatin	simvastatin	NOUN
cuesj-1234	7	7	:	:	PUNCT
cuesj-1234	7	8	docusate	docusate	NOUN
cuesj-1234	7	9	:	:	PUNCT
cuesj-1234	7	10	isoleucine	isoleucine	NOUN
cuesj-1234	7	11	increased	increase	VERB
cuesj-1234	7	12	solubility	solubility	NOUN
cuesj-1234	7	13	more	more	ADJ
cuesj-1234	7	14	than	than	ADP
cuesj-1234	7	15	7	7	NUM
cuesj-1234	7	16	-	-	NOUN
cuesj-1234	7	17	fold	fold	ADJ
cuesj-1234	7	18	,	,	PUNCT
cuesj-1234	7	19	and	and	CCONJ
cuesj-1234	7	20	a	a	DET
cuesj-1234	7	21	4:3:3	4:3:3	NUM
cuesj-1234	7	22	ratio	ratio	NOUN
cuesj-1234	7	23	increased	increase	VERB
cuesj-1234	7	24	the	the	DET
cuesj-1234	7	25	solubility	solubility	NOUN
cuesj-1234	7	26	nearly	nearly	ADV
cuesj-1234	7	27	5	5	NUM
cuesj-1234	7	28	-	-	NUM
cuesj-1234	7	29	fold	fold	ADJ
cuesj-1234	7	30	.	.	PUNCT
cuesj-1234	8	1	the	the	DET
cuesj-1234	8	2	synergistic	synergistic	ADJ
cuesj-1234	8	3	effect	effect	NOUN
cuesj-1234	8	4	of	of	ADP
cuesj-1234	8	5	docusate	docusate	NOUN
cuesj-1234	8	6	and	and	CCONJ
cuesj-1234	8	7	isoleucine	isoleucine	NOUN
cuesj-1234	8	8	showed	show	VERB
cuesj-1234	8	9	improvement	improvement	NOUN
cuesj-1234	8	10	in	in	ADP
cuesj-1234	8	11	the	the	DET
cuesj-1234	8	12	solubility	solubility	NOUN
cuesj-1234	8	13	of	of	ADP
cuesj-1234	8	14	simvastatin	simvastatin	NOUN
cuesj-1234	8	15	at	at	ADP
cuesj-1234	8	16	room	room	NOUN
cuesj-1234	8	17	temperature	temperature	NOUN
cuesj-1234	8	18	when	when	SCONJ
cuesj-1234	8	19	incorporated	incorporate	VERB
cuesj-1234	8	20	in	in	ADP
cuesj-1234	8	21	relatively	relatively	ADV
cuesj-1234	8	22	low	low	ADJ
cuesj-1234	8	23	ratios	ratio	NOUN
cuesj-1234	8	24	.	.	PUNCT
cuesj-1234	9	1	keywords	keyword	NOUN
cuesj-1234	9	2	:	:	PUNCT
cuesj-1234	9	3	l	l	NOUN
cuesj-1234	9	4	-	-	NOUN
cuesj-1234	9	5	isoleucine	isoleucine	NOUN
cuesj-1234	9	6	,	,	PUNCT
cuesj-1234	9	7	simvastatin	simvastatin	NOUN
cuesj-1234	9	8	,	,	PUNCT
cuesj-1234	9	9	sodium	sodium	NOUN
cuesj-1234	9	10	docusate	docusate	NOUN
cuesj-1234	9	11	,	,	PUNCT
cuesj-1234	9	12	solubility	solubility	NOUN
cuesj-1234	9	13	introduction	introduction	NOUN
cuesj-1234	9	14	drugs	drug	NOUN
cuesj-1234	9	15	that	that	PRON
cuesj-1234	9	16	are	be	AUX
cuesj-1234	9	17	easily	easily	ADV
cuesj-1234	9	18	or	or	CCONJ
cuesj-1234	9	19	completely	completely	ADV
cuesj-1234	9	20	soluble	soluble	ADJ
cuesj-1234	9	21	in	in	ADP
cuesj-1234	9	22	the	the	DET
cuesj-1234	9	23	gastrointestinal	gastrointestinal	ADJ
cuesj-1234	9	24	(	(	PUNCT
cuesj-1234	9	25	gi	gi	NOUN
cuesj-1234	9	26	)	)	PUNCT
cuesj-1234	9	27	media	medium	NOUN
cuesj-1234	9	28	show	show	VERB
cuesj-1234	9	29	complete	complete	ADJ
cuesj-1234	9	30	oral	oral	ADJ
cuesj-1234	9	31	absorption	absorption	NOUN
cuesj-1234	9	32	,	,	PUNCT
cuesj-1234	9	33	resulting	result	VERB
cuesj-1234	9	34	in	in	ADP
cuesj-1234	9	35	high	high	ADJ
cuesj-1234	9	36	plasma	plasma	NOUN
cuesj-1234	9	37	levels	level	NOUN
cuesj-1234	9	38	or	or	CCONJ
cuesj-1234	9	39	bioavailability	bioavailability	NOUN
cuesj-1234	9	40	.	.	PUNCT
cuesj-1234	10	1	about	about	ADV
cuesj-1234	10	2	40	40	NUM
cuesj-1234	10	3	%	%	NOUN
cuesj-1234	10	4	of	of	ADP
cuesj-1234	10	5	drugs	drug	NOUN
cuesj-1234	10	6	are	be	AUX
cuesj-1234	10	7	practically	practically	ADV
cuesj-1234	10	8	insoluble	insoluble	ADJ
cuesj-1234	10	9	in	in	ADP
cuesj-1234	10	10	water	water	NOUN
cuesj-1234	10	11	and	and	CCONJ
cuesj-1234	10	12	as	as	SCONJ
cuesj-1234	10	13	such	such	ADJ
cuesj-1234	10	14	have	have	VERB
cuesj-1234	10	15	slow	slow	ADJ
cuesj-1234	10	16	absorption	absorption	NOUN
cuesj-1234	10	17	,	,	PUNCT
cuesj-1234	10	18	which	which	PRON
cuesj-1234	10	19	results	result	VERB
cuesj-1234	10	20	in	in	ADP
cuesj-1234	10	21	inadequate	inadequate	ADJ
cuesj-1234	10	22	and	and	CCONJ
cuesj-1234	10	23	unequal	unequal	ADJ
cuesj-1234	10	24	bioavailability	bioavailability	NOUN
cuesj-1234	10	25	,	,	PUNCT
cuesj-1234	10	26	and	and	CCONJ
cuesj-1234	10	27	gi	gi	VERB
cuesj-1234	10	28	toxicity.[1	toxicity.[1	NOUN
cuesj-1234	10	29	]	]	PUNCT
cuesj-1234	10	30	thus	thus	ADV
cuesj-1234	10	31	,	,	PUNCT
cuesj-1234	10	32	the	the	DET
cuesj-1234	10	33	most	most	ADV
cuesj-1234	10	34	critical	critical	ADJ
cuesj-1234	10	35	phase	phase	NOUN
cuesj-1234	10	36	and	and	CCONJ
cuesj-1234	10	37	important	important	ADJ
cuesj-1234	10	38	aspect	aspect	NOUN
cuesj-1234	10	39	of	of	ADP
cuesj-1234	10	40	drug	drug	NOUN
cuesj-1234	10	41	development	development	NOUN
cuesj-1234	10	42	,	,	PUNCT
cuesj-1234	10	43	especially	especially	ADV
cuesj-1234	10	44	for	for	ADP
cuesj-1234	10	45	oral	oral	ADJ
cuesj-1234	10	46	formulations	formulation	NOUN
cuesj-1234	10	47	,	,	PUNCT
cuesj-1234	10	48	is	be	AUX
cuesj-1234	10	49	the	the	DET
cuesj-1234	10	50	improvement	improvement	NOUN
cuesj-1234	10	51	of	of	ADP
cuesj-1234	10	52	drug	drug	NOUN
cuesj-1234	10	53	solubility	solubility	NOUN
cuesj-1234	10	54	and	and	CCONJ
cuesj-1234	10	55	,	,	PUNCT
cuesj-1234	10	56	consequently	consequently	ADV
cuesj-1234	10	57	,	,	PUNCT
cuesj-1234	10	58	its	its	PRON
cuesj-1234	10	59	oral	oral	ADJ
cuesj-1234	10	60	bioavailability	bioavailability	NOUN
cuesj-1234	10	61	.	.	PUNCT
cuesj-1234	11	1	bioavailability	bioavailability	NOUN
cuesj-1234	11	2	is	be	AUX
cuesj-1234	11	3	defined	define	VERB
cuesj-1234	11	4	as	as	ADP
cuesj-1234	11	5	the	the	DET
cuesj-1234	11	6	amount	amount	NOUN
cuesj-1234	11	7	of	of	ADP
cuesj-1234	11	8	therapeutically	therapeutically	ADV
cuesj-1234	11	9	active	active	ADJ
cuesj-1234	11	10	drug	drug	NOUN
cuesj-1234	11	11	that	that	PRON
cuesj-1234	11	12	enters	enter	VERB
cuesj-1234	11	13	the	the	DET
cuesj-1234	11	14	bloodstream	bloodstream	NOUN
cuesj-1234	11	15	,	,	PUNCT
cuesj-1234	11	16	or	or	CCONJ
cuesj-1234	11	17	systemic	systemic	ADJ
cuesj-1234	11	18	circulation	circulation	NOUN
cuesj-1234	11	19	,	,	PUNCT
cuesj-1234	11	20	and	and	CCONJ
cuesj-1234	11	21	is	be	AUX
cuesj-1234	11	22	readily	readily	ADV
cuesj-1234	11	23	available	available	ADJ
cuesj-1234	11	24	at	at	ADP
cuesj-1234	11	25	the	the	DET
cuesj-1234	11	26	drug	drug	NOUN
cuesj-1234	11	27	’s	’s	PART
cuesj-1234	11	28	site	site	NOUN
cuesj-1234	11	29	of	of	ADP
cuesj-1234	11	30	action	action	NOUN
cuesj-1234	11	31	.	.	PUNCT
cuesj-1234	12	1	there	there	PRON
cuesj-1234	12	2	are	be	VERB
cuesj-1234	12	3	two	two	NUM
cuesj-1234	12	4	reasons	reason	NOUN
cuesj-1234	12	5	put	put	VERB
cuesj-1234	12	6	forth	forth	ADP
cuesj-1234	12	7	for	for	ADP
cuesj-1234	12	8	the	the	DET
cuesj-1234	12	9	low	low	ADJ
cuesj-1234	12	10	aqueous	aqueous	ADJ
cuesj-1234	12	11	solubility	solubility	NOUN
cuesj-1234	12	12	of	of	ADP
cuesj-1234	12	13	drugs:[2	drugs:[2	PROPN
cuesj-1234	12	14	]	]	X
cuesj-1234	12	15	(	(	PUNCT
cuesj-1234	12	16	a	a	X
cuesj-1234	12	17	)	)	PUNCT
cuesj-1234	12	18	high	high	ADJ
cuesj-1234	12	19	lipophilicity	lipophilicity	NOUN
cuesj-1234	12	20	and	and	CCONJ
cuesj-1234	12	21	(	(	PUNCT
cuesj-1234	12	22	b	b	NOUN
cuesj-1234	12	23	)	)	PUNCT
cuesj-1234	12	24	strong	strong	ADJ
cuesj-1234	12	25	intermolecular	intermolecular	ADJ
cuesj-1234	12	26	forces	force	NOUN
cuesj-1234	12	27	that	that	PRON
cuesj-1234	12	28	cause	cause	VERB
cuesj-1234	12	29	the	the	DET
cuesj-1234	12	30	difficulty	difficulty	NOUN
cuesj-1234	12	31	in	in	ADP
cuesj-1234	12	32	solubilization	solubilization	NOUN
cuesj-1234	12	33	of	of	ADP
cuesj-1234	12	34	drugs.[3	drugs.[3	NOUN
cuesj-1234	12	35	]	]	X
cuesj-1234	12	36	dissolution	dissolution	NOUN
cuesj-1234	12	37	,	,	PUNCT
cuesj-1234	12	38	which	which	PRON
cuesj-1234	12	39	depends	depend	VERB
cuesj-1234	12	40	on	on	ADP
cuesj-1234	12	41	solubility	solubility	NOUN
cuesj-1234	12	42	,	,	PUNCT
cuesj-1234	12	43	is	be	AUX
cuesj-1234	12	44	the	the	DET
cuesj-1234	12	45	rate	rate	NOUN
cuesj-1234	12	46	-	-	PUNCT
cuesj-1234	12	47	limiting	limit	VERB
cuesj-1234	12	48	step	step	NOUN
cuesj-1234	12	49	for	for	ADP
cuesj-1234	12	50	both	both	CCONJ
cuesj-1234	12	51	the	the	DET
cuesj-1234	12	52	rate	rate	NOUN
cuesj-1234	12	53	and	and	CCONJ
cuesj-1234	12	54	degree	degree	NOUN
cuesj-1234	12	55	of	of	ADP
cuesj-1234	12	56	drug	drug	NOUN
cuesj-1234	12	57	absorption	absorption	NOUN
cuesj-1234	12	58	.	.	PUNCT
cuesj-1234	13	1	figure	figure	NOUN
cuesj-1234	13	2	1	1	NUM
cuesj-1234	13	3	shows	show	VERB
cuesj-1234	13	4	an	an	DET
cuesj-1234	13	5	important	important	ADJ
cuesj-1234	13	6	insight	insight	NOUN
cuesj-1234	13	7	into	into	ADP
cuesj-1234	13	8	the	the	DET
cuesj-1234	13	9	relationship	relationship	NOUN
cuesj-1234	13	10	between	between	ADP
cuesj-1234	13	11	solubility	solubility	NOUN
cuesj-1234	13	12	and	and	CCONJ
cuesj-1234	13	13	permeability	permeability	NOUN
cuesj-1234	13	14	.	.	PUNCT
cuesj-1234	14	1	as	as	SCONJ
cuesj-1234	14	2	shown	show	VERB
cuesj-1234	14	3	in	in	ADP
cuesj-1234	14	4	figure	figure	NOUN
cuesj-1234	14	5	1	1	NUM
cuesj-1234	14	6	,	,	PUNCT
cuesj-1234	14	7	the	the	DET
cuesj-1234	14	8	two	two	NUM
cuesj-1234	14	9	factors	factor	NOUN
cuesj-1234	14	10	of	of	ADP
cuesj-1234	14	11	solubility	solubility	NOUN
cuesj-1234	14	12	and	and	CCONJ
cuesj-1234	14	13	absorption	absorption	NOUN
cuesj-1234	14	14	form	form	NOUN
cuesj-1234	14	15	four	four	NUM
cuesj-1234	14	16	classes	class	NOUN
cuesj-1234	14	17	of	of	ADP
cuesj-1234	14	18	drugs	drug	NOUN
cuesj-1234	14	19	.	.	PUNCT
cuesj-1234	15	1	many	many	ADJ
cuesj-1234	15	2	classic	classic	ADJ
cuesj-1234	15	3	drugs	drug	NOUN
cuesj-1234	15	4	,	,	PUNCT
cuesj-1234	15	5	such	such	ADJ
cuesj-1234	15	6	as	as	ADP
cuesj-1234	15	7	digoxin	digoxin	NOUN
cuesj-1234	15	8	,	,	PUNCT
cuesj-1234	15	9	piroxicam	piroxicam	ADJ
cuesj-1234	15	10	,	,	PUNCT
cuesj-1234	15	11	chlorothiazide	chlorothiazide	ADJ
cuesj-1234	15	12	,	,	PUNCT
cuesj-1234	15	13	and	and	CCONJ
cuesj-1234	15	14	griseofulvin	griseofulvin	NOUN
cuesj-1234	15	15	,	,	PUNCT
cuesj-1234	15	16	as	as	ADV
cuesj-1234	15	17	well	well	ADV
cuesj-1234	15	18	as	as	ADP
cuesj-1234	15	19	most	most	ADJ
cuesj-1234	15	20	new	new	ADJ
cuesj-1234	15	21	innovative	innovative	ADJ
cuesj-1234	15	22	pharmacological	pharmacological	NOUN
cuesj-1234	15	23	compounds	compound	NOUN
cuesj-1234	15	24	,	,	PUNCT
cuesj-1234	15	25	exhibit	exhibit	VERB
cuesj-1234	15	26	poor	poor	ADJ
cuesj-1234	15	27	water	water	NOUN
cuesj-1234	15	28	solubility.[4	solubility.[4	NOUN
cuesj-1234	15	29	]	]	PUNCT
cuesj-1234	15	30	here	here	ADV
cuesj-1234	15	31	,	,	PUNCT
cuesj-1234	15	32	excipients	excipient	NOUN
cuesj-1234	15	33	play	play	VERB
cuesj-1234	15	34	a	a	DET
cuesj-1234	15	35	significant	significant	ADJ
cuesj-1234	15	36	role	role	NOUN
cuesj-1234	15	37	in	in	ADP
cuesj-1234	15	38	improving	improve	VERB
cuesj-1234	15	39	these	these	DET
cuesj-1234	15	40	compounds	compound	NOUN
cuesj-1234	15	41	.	.	PUNCT
cuesj-1234	16	1	in	in	ADP
cuesj-1234	16	2	oral	oral	ADJ
cuesj-1234	16	3	medications	medication	NOUN
cuesj-1234	16	4	like	like	ADP
cuesj-1234	16	5	simvastatin	simvastatin	NOUN
cuesj-1234	16	6	,	,	PUNCT
cuesj-1234	16	7	the	the	DET
cuesj-1234	16	8	drug	drug	NOUN
cuesj-1234	16	9	is	be	AUX
cuesj-1234	16	10	required	require	VERB
cuesj-1234	16	11	to	to	PART
cuesj-1234	16	12	be	be	AUX
cuesj-1234	16	13	dissolved	dissolve	VERB
cuesj-1234	16	14	in	in	ADP
cuesj-1234	16	15	gastric	gastric	ADJ
cuesj-1234	16	16	fluids	fluid	NOUN
cuesj-1234	16	17	to	to	PART
cuesj-1234	16	18	have	have	VERB
cuesj-1234	16	19	better	well	ADJ
cuesj-1234	16	20	absorption	absorption	NOUN
cuesj-1234	16	21	and	and	CCONJ
cuesj-1234	16	22	bioavailability	bioavailability	NOUN
cuesj-1234	16	23	.	.	PUNCT
cuesj-1234	17	1	low	low	ADJ
cuesj-1234	17	2	aqueous	aqueous	ADJ
cuesj-1234	17	3	solubility	solubility	NOUN
cuesj-1234	17	4	is	be	AUX
cuesj-1234	17	5	one	one	NUM
cuesj-1234	17	6	of	of	ADP
cuesj-1234	17	7	the	the	DET
cuesj-1234	17	8	features	feature	NOUN
cuesj-1234	17	9	of	of	ADP
cuesj-1234	17	10	bcs	bcs	NOUN
cuesj-1234	17	11	class	class	PROPN
cuesj-1234	17	12	ii	ii	PROPN
cuesj-1234	17	13	and	and	CCONJ
cuesj-1234	17	14	iv	iv	NUM
cuesj-1234	17	15	drugs	drug	NOUN
cuesj-1234	17	16	and	and	CCONJ
cuesj-1234	17	17	is	be	AUX
cuesj-1234	17	18	a	a	DET
cuesj-1234	17	19	significant	significant	ADJ
cuesj-1234	17	20	hurdle	hurdle	NOUN
cuesj-1234	17	21	for	for	ADP
cuesj-1234	17	22	drug	drug	NOUN
cuesj-1234	17	23	development	development	NOUN
cuesj-1234	17	24	and	and	CCONJ
cuesj-1234	17	25	delivery	delivery	NOUN
cuesj-1234	17	26	.	.	PUNCT
cuesj-1234	18	1	multiple	multiple	ADJ
cuesj-1234	18	2	technologies	technology	NOUN
cuesj-1234	18	3	have	have	AUX
cuesj-1234	18	4	been	be	AUX
cuesj-1234	18	5	implemented	implement	VERB
cuesj-1234	18	6	to	to	PART
cuesj-1234	18	7	enhance	enhance	VERB
cuesj-1234	18	8	the	the	DET
cuesj-1234	18	9	bioavailability	bioavailability	NOUN
cuesj-1234	18	10	of	of	ADP
cuesj-1234	18	11	poorly	poorly	ADV
cuesj-1234	18	12	water	water	NOUN
cuesj-1234	18	13	-	-	PUNCT
cuesj-1234	18	14	soluble	soluble	ADJ
cuesj-1234	18	15	drug	drug	NOUN
cuesj-1234	18	16	compounds	compound	NOUN
cuesj-1234	18	17	,	,	PUNCT
cuesj-1234	18	18	including	include	VERB
cuesj-1234	18	19	solid	solid	ADJ
cuesj-1234	18	20	dispersions	dispersion	NOUN
cuesj-1234	18	21	,	,	PUNCT
cuesj-1234	18	22	lipid	lipid	NOUN
cuesj-1234	18	23	-	-	PUNCT
cuesj-1234	18	24	based	base	VERB
cuesj-1234	18	25	formulations	formulation	NOUN
cuesj-1234	18	26	,	,	PUNCT
cuesj-1234	18	27	co	co	NOUN
cuesj-1234	18	28	-	-	NOUN
cuesj-1234	18	29	precipitation	precipitation	ADJ
cuesj-1234	18	30	,	,	PUNCT
cuesj-1234	18	31	micronization	micronization	NOUN
cuesj-1234	18	32	,	,	PUNCT
cuesj-1234	18	33	solvent	solvent	ADJ
cuesj-1234	18	34	evaporation	evaporation	NOUN
cuesj-1234	18	35	,	,	PUNCT
cuesj-1234	18	36	liquid	liquid	ADJ
cuesj-1234	18	37	–	–	PUNCT
cuesj-1234	18	38	solid	solid	ADJ
cuesj-1234	18	39	compacts	compact	NOUN
cuesj-1234	18	40	,	,	PUNCT
cuesj-1234	18	41	and	and	CCONJ
cuesj-1234	18	42	solvent	solvent	ADJ
cuesj-1234	18	43	deposition	deposition	NOUN
cuesj-1234	18	44	inclusion	inclusion	NOUN
cuesj-1234	18	45	complexation	complexation	NOUN
cuesj-1234	18	46	.	.	PUNCT
cuesj-1234	19	1	some	some	DET
cuesj-1234	19	2	commonly	commonly	ADV
cuesj-1234	19	3	used	use	VERB
cuesj-1234	19	4	excipients	excipient	NOUN
cuesj-1234	19	5	are	be	AUX
cuesj-1234	19	6	hypromellose	hypromellose	PROPN
cuesj-1234	19	7	acetate	acetate	NOUN
cuesj-1234	19	8	succinate	succinate	NOUN
cuesj-1234	19	9	,	,	PUNCT
cuesj-1234	19	10	cyclodextrin	cyclodextrin	NOUN
cuesj-1234	19	11	,	,	PUNCT
cuesj-1234	19	12	povidone	povidone	NOUN
cuesj-1234	19	13	,	,	PUNCT
cuesj-1234	19	14	hydroxypropyl	hydroxypropyl	NOUN
cuesj-1234	19	15	cellulose	cellulose	NOUN
cuesj-1234	19	16	,	,	PUNCT
cuesj-1234	19	17	polyethylene	polyethylene	NOUN
cuesj-1234	19	18	glycol	glycol	NOUN
cuesj-1234	19	19	,	,	PUNCT
cuesj-1234	19	20	sodium	sodium	NOUN
cuesj-1234	19	21	lauryl	lauryl	NOUN
cuesj-1234	19	22	sulfate	sulfate	NOUN
cuesj-1234	19	23	,	,	PUNCT
cuesj-1234	19	24	and	and	CCONJ
cuesj-1234	19	25	more.[6	more.[6	ADP
cuesj-1234	19	26	]	]	X
cuesj-1234	19	27	corresponding	correspond	VERB
cuesj-1234	19	28	author	author	NOUN
cuesj-1234	19	29	:	:	PUNCT
cuesj-1234	19	30	maysra	maysra	PROPN
cuesj-1234	19	31	a.	a.	PROPN
cuesj-1234	19	32	al	al	PROPN
cuesj-1234	19	33	-	-	PUNCT
cuesj-1234	19	34	jumaili	jumaili	PROPN
cuesj-1234	19	35	,	,	PUNCT
cuesj-1234	19	36	department	department	NOUN
cuesj-1234	19	37	of	of	ADP
cuesj-1234	19	38	pharmaceutics	pharmaceutic	NOUN
cuesj-1234	19	39	,	,	PUNCT
cuesj-1234	19	40	college	college	NOUN
cuesj-1234	19	41	of	of	ADP
cuesj-1234	19	42	pharmacy	pharmacy	NOUN
cuesj-1234	19	43	,	,	PUNCT
cuesj-1234	19	44	hawler	hawler	PROPN
cuesj-1234	19	45	medical	medical	PROPN
cuesj-1234	19	46	university	university	PROPN
cuesj-1234	19	47	,	,	PUNCT
cuesj-1234	19	48	erbil	erbil	PROPN
cuesj-1234	19	49	,	,	PUNCT
cuesj-1234	19	50	iraq	iraq	PROPN
cuesj-1234	19	51	.	.	PUNCT
cuesj-1234	20	1	e	e	X
cuesj-1234	20	2	-	-	NOUN
cuesj-1234	20	3	mail	mail	NOUN
cuesj-1234	20	4	:	:	PUNCT
cuesj-1234	20	5	maysra.ahmed@ukh.edu.krd	maysra.ahmed@ukh.edu.krd	NOUN
cuesj-1234	20	6	received	receive	VERB
cuesj-1234	20	7	:	:	PUNCT
cuesj-1234	20	8	june	june	PROPN
cuesj-1234	20	9	26	26	NUM
cuesj-1234	20	10	,	,	PUNCT
cuesj-1234	20	11	2024	2024	NUM
cuesj-1234	20	12	accepted	accept	VERB
cuesj-1234	20	13	:	:	PUNCT
cuesj-1234	20	14	march	march	PROPN
cuesj-1234	20	15	11	11	NUM
cuesj-1234	20	16	,	,	PUNCT
cuesj-1234	20	17	2025	2025	NUM
cuesj-1234	20	18	published	publish	VERB
cuesj-1234	20	19	:	:	PUNCT
cuesj-1234	20	20	july	july	PROPN
cuesj-1234	20	21	25	25	NUM
cuesj-1234	20	22	,	,	PUNCT
cuesj-1234	20	23	2025	2025	NUM
cuesj-1234	20	24	doi	doi	NOUN
cuesj-1234	20	25	:	:	PUNCT
cuesj-1234	20	26	10.24086	10.24086	NUM
cuesj-1234	20	27	/	/	SYM
cuesj-1234	20	28	cuesj.v9n2y2025.pp26	cuesj.v9n2y2025.pp26	ADP
cuesj-1234	20	29	-	-	PUNCT
cuesj-1234	20	30	32	32	NUM
cuesj-1234	20	31	copyright	copyright	NOUN
cuesj-1234	20	32	©	©	PROPN
cuesj-1234	20	33	2025	2025	NUM
cuesj-1234	20	34	maysra	maysra	PROPN
cuesj-1234	20	35	a.	a.	PROPN
cuesj-1234	20	36	al	al	PROPN
cuesj-1234	20	37	-	-	PUNCT
cuesj-1234	20	38	jumaili	jumaili	PROPN
cuesj-1234	20	39	,	,	PUNCT
cuesj-1234	20	40	suzan	suzan	PROPN
cuesj-1234	20	41	n.	n.	PROPN
cuesj-1234	20	42	anwer	anwer	PROPN
cuesj-1234	20	43	alamdar	alamdar	PROPN
cuesj-1234	20	44	,	,	PUNCT
cuesj-1234	20	45	marwa	marwa	PROPN
cuesj-1234	20	46	f.	f.	PROPN
cuesj-1234	20	47	noori	noori	PROPN
cuesj-1234	20	48	,	,	PUNCT
cuesj-1234	20	49	hewa	hewa	PROPN
cuesj-1234	20	50	a.	a.	PROPN
cuesj-1234	20	51	hamad	hamad	PROPN
cuesj-1234	20	52	ameen	ameen	PROPN
cuesj-1234	20	53	,	,	PUNCT
cuesj-1234	20	54	muhamed	muhamed	PROPN
cuesj-1234	20	55	a.	a.	NOUN
cuesj-1234	20	56	abbas	abbas	PROPN
cuesj-1234	20	57	.	.	PUNCT
cuesj-1234	21	1	this	this	PRON
cuesj-1234	21	2	is	be	AUX
cuesj-1234	21	3	an	an	DET
cuesj-1234	21	4	open	open	ADJ
cuesj-1234	21	5	-	-	PUNCT
cuesj-1234	21	6	access	access	NOUN
cuesj-1234	21	7	article	article	NOUN
cuesj-1234	21	8	distributed	distribute	VERB
cuesj-1234	21	9	under	under	ADP
cuesj-1234	21	10	the	the	DET
cuesj-1234	21	11	creative	creative	ADJ
cuesj-1234	21	12	commons	common	NOUN
cuesj-1234	21	13	attribution	attribution	NOUN
cuesj-1234	21	14	license	license	NOUN
cuesj-1234	21	15	.	.	PUNCT
cuesj-1234	22	1	cihan	cihan	VERB
cuesj-1234	22	2	university	university	NOUN
cuesj-1234	22	3	-	-	PUNCT
cuesj-1234	22	4	erbil	erbil	PROPN
cuesj-1234	22	5	scientific	scientific	ADJ
cuesj-1234	22	6	journal	journal	NOUN
cuesj-1234	22	7	(	(	PUNCT
cuesj-1234	22	8	cuesj	cuesj	PROPN
cuesj-1234	22	9	)	)	PUNCT
cuesj-1234	22	10	al	al	PROPN
cuesj-1234	22	11	-	-	PUNCT
cuesj-1234	22	12	jumaili	jumaili	PROPN
cuesj-1234	22	13	,	,	PUNCT
cuesj-1234	22	14	et	et	PROPN
cuesj-1234	22	15	al	al	PROPN
cuesj-1234	22	16	.	.	PROPN
cuesj-1234	22	17	:	:	PUNCT
cuesj-1234	23	1	enhancing	enhance	VERB
cuesj-1234	23	2	solubility	solubility	NOUN
cuesj-1234	23	3	of	of	ADP
cuesj-1234	23	4	simvastatin	simvastatin	NOUN
cuesj-1234	23	5	with	with	ADP
cuesj-1234	23	6	l	l	NOUN
cuesj-1234	23	7	-	-	NOUN
cuesj-1234	23	8	isoleucine	isoleucine	ADJ
cuesj-1234	23	9	and	and	CCONJ
cuesj-1234	23	10	sodium	sodium	NOUN
cuesj-1234	23	11	docusate	docusate	NOUN
cuesj-1234	23	12	27	27	NUM
cuesj-1234	23	13	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	23	14	cuesj	cuesj	NOUN
cuesj-1234	23	15	2025	2025	NUM
cuesj-1234	23	16	,	,	PUNCT
cuesj-1234	23	17	9	9	NUM
cuesj-1234	23	18	(	(	PUNCT
cuesj-1234	23	19	2	2	NUM
cuesj-1234	23	20	):	):	PUNCT
cuesj-1234	23	21	26	26	NUM
cuesj-1234	23	22	-	-	SYM
cuesj-1234	23	23	32	32	NUM
cuesj-1234	23	24	figure	figure	NOUN
cuesj-1234	23	25	2	2	NUM
cuesj-1234	23	26	shows	show	VERB
cuesj-1234	23	27	the	the	DET
cuesj-1234	23	28	classification	classification	NOUN
cuesj-1234	23	29	of	of	ADP
cuesj-1234	23	30	drugs	drug	NOUN
cuesj-1234	23	31	based	base	VERB
cuesj-1234	23	32	on	on	ADP
cuesj-1234	23	33	solubility	solubility	NOUN
cuesj-1234	23	34	in	in	ADP
cuesj-1234	23	35	water	water	NOUN
cuesj-1234	23	36	.	.	PUNCT
cuesj-1234	24	1	simvastatin	simvastatin	PROPN
cuesj-1234	24	2	is	be	AUX
cuesj-1234	24	3	a	a	DET
cuesj-1234	24	4	chemical	chemical	ADJ
cuesj-1234	24	5	derivative	derivative	NOUN
cuesj-1234	24	6	of	of	ADP
cuesj-1234	24	7	lovastatin	lovastatin	PROPN
cuesj-1234	24	8	.	.	PUNCT
cuesj-1234	25	1	it	it	PRON
cuesj-1234	25	2	is	be	AUX
cuesj-1234	25	3	a	a	DET
cuesj-1234	25	4	prodrug	prodrug	NOUN
cuesj-1234	25	5	that	that	PRON
cuesj-1234	25	6	lowers	lower	VERB
cuesj-1234	25	7	cholesterol	cholesterol	NOUN
cuesj-1234	25	8	levels	level	NOUN
cuesj-1234	25	9	by	by	ADP
cuesj-1234	25	10	inhibiting	inhibit	VERB
cuesj-1234	25	11	liver	liver	NOUN
cuesj-1234	25	12	cholesterol	cholesterol	NOUN
cuesj-1234	25	13	synthesis	synthesis	NOUN
cuesj-1234	25	14	through	through	ADP
cuesj-1234	25	15	inhibition	inhibition	NOUN
cuesj-1234	25	16	of	of	ADP
cuesj-1234	25	17	hmg	hmg	NOUN
cuesj-1234	25	18	-	-	PUNCT
cuesj-1234	25	19	coa	coa	NOUN
cuesj-1234	25	20	reductase	reductase	NOUN
cuesj-1234	25	21	,	,	PUNCT
cuesj-1234	25	22	and	and	CCONJ
cuesj-1234	25	23	also	also	ADV
cuesj-1234	25	24	by	by	ADP
cuesj-1234	25	25	increasing	increase	VERB
cuesj-1234	25	26	low	low	ADJ
cuesj-1234	25	27	-	-	PUNCT
cuesj-1234	25	28	density	density	NOUN
cuesj-1234	25	29	lipoprotein	lipoprotein	ADJ
cuesj-1234	25	30	(	(	PUNCT
cuesj-1234	25	31	ldl	ldl	NOUN
cuesj-1234	25	32	)	)	PUNCT
cuesj-1234	25	33	receptors	receptor	NOUN
cuesj-1234	25	34	present	present	ADJ
cuesj-1234	25	35	on	on	ADP
cuesj-1234	25	36	the	the	DET
cuesj-1234	25	37	liver	liver	NOUN
cuesj-1234	25	38	’s	’s	PART
cuesj-1234	25	39	surface	surface	NOUN
cuesj-1234	25	40	.	.	PUNCT
cuesj-1234	26	1	simvastatin	simvastatin	PROPN
cuesj-1234	26	2	,	,	PUNCT
cuesj-1234	26	3	in	in	ADP
cuesj-1234	26	4	patients	patient	NOUN
cuesj-1234	26	5	with	with	ADP
cuesj-1234	26	6	heterozygous	heterozygous	ADJ
cuesj-1234	26	7	familial	familial	ADJ
cuesj-1234	26	8	hypercholesterolemia	hypercholesterolemia	NOUN
cuesj-1234	26	9	,	,	PUNCT
cuesj-1234	26	10	reduces	reduce	VERB
cuesj-1234	26	11	the	the	DET
cuesj-1234	26	12	total	total	ADJ
cuesj-1234	26	13	cholesterol	cholesterol	NOUN
cuesj-1234	26	14	and	and	CCONJ
cuesj-1234	26	15	ldl	ldl	NOUN
cuesj-1234	26	16	cholesterol	cholesterol	NOUN
cuesj-1234	26	17	,	,	PUNCT
cuesj-1234	26	18	and	and	CCONJ
cuesj-1234	26	19	as	as	ADP
cuesj-1234	26	20	a	a	DET
cuesj-1234	26	21	secondary	secondary	ADJ
cuesj-1234	26	22	action	action	NOUN
cuesj-1234	26	23	tends	tend	VERB
cuesj-1234	26	24	to	to	PART
cuesj-1234	26	25	reduce	reduce	VERB
cuesj-1234	26	26	triglycerides	triglyceride	NOUN
cuesj-1234	26	27	and	and	CCONJ
cuesj-1234	26	28	increase	increase	VERB
cuesj-1234	26	29	high	high	ADJ
cuesj-1234	26	30	-	-	PUNCT
cuesj-1234	26	31	density	density	NOUN
cuesj-1234	26	32	lipoprotein	lipoprotein	ADJ
cuesj-1234	26	33	cholesterol	cholesterol	NOUN
cuesj-1234	26	34	levels	level	NOUN
cuesj-1234	26	35	.	.	PUNCT
cuesj-1234	27	1	this	this	DET
cuesj-1234	27	2	medication	medication	NOUN
cuesj-1234	27	3	is	be	AUX
cuesj-1234	27	4	also	also	ADV
cuesj-1234	27	5	effective	effective	ADJ
cuesj-1234	27	6	in	in	ADP
cuesj-1234	27	7	patients	patient	NOUN
cuesj-1234	27	8	with	with	ADP
cuesj-1234	27	9	familial	familial	ADJ
cuesj-1234	27	10	dysbetalipoproteinemia	dysbetalipoproteinemia	NOUN
cuesj-1234	27	11	,	,	PUNCT
cuesj-1234	27	12	polygenic	polygenic	ADJ
cuesj-1234	27	13	hypercholesterolemia	hypercholesterolemia	NOUN
cuesj-1234	27	14	,	,	PUNCT
cuesj-1234	27	15	and	and	CCONJ
cuesj-1234	27	16	nephrotic	nephrotic	ADJ
cuesj-1234	27	17	syndrome	syndrome	NOUN
cuesj-1234	27	18	where	where	SCONJ
cuesj-1234	27	19	an	an	DET
cuesj-1234	27	20	excess	excess	NOUN
cuesj-1234	27	21	of	of	ADP
cuesj-1234	27	22	helpful	helpful	ADJ
cuesj-1234	27	23	proteins	protein	NOUN
cuesj-1234	27	24	is	be	AUX
cuesj-1234	27	25	lost.[8	lost.[8	NOUN
cuesj-1234	27	26	]	]	PUNCT
cuesj-1234	27	27	chemically	chemically	ADV
cuesj-1234	27	28	,	,	PUNCT
cuesj-1234	27	29	simvastatin	simvastatin	PROPN
cuesj-1234	27	30	is	be	AUX
cuesj-1234	27	31	a	a	DET
cuesj-1234	27	32	part	part	NOUN
cuesj-1234	27	33	of	of	ADP
cuesj-1234	27	34	the	the	DET
cuesj-1234	27	35	class	class	NOUN
cuesj-1234	27	36	of	of	ADP
cuesj-1234	27	37	hexahydronaphthalenes	hexahydronaphthalene	NOUN
cuesj-1234	27	38	that	that	PRON
cuesj-1234	27	39	includes	include	VERB
cuesj-1234	27	40	lovastatin	lovastatin	NOUN
cuesj-1234	27	41	,	,	PUNCT
cuesj-1234	27	42	in	in	ADP
cuesj-1234	27	43	which	which	PRON
cuesj-1234	27	44	the	the	DET
cuesj-1234	27	45	2	2	NUM
cuesj-1234	27	46	-	-	PUNCT
cuesj-1234	27	47	methylbutyrate	methylbutyrate	NOUN
cuesj-1234	27	48	ester	ester	NOUN
cuesj-1234	27	49	moiety	moiety	NOUN
cuesj-1234	27	50	has	have	AUX
cuesj-1234	27	51	been	be	AUX
cuesj-1234	27	52	replaced	replace	VERB
cuesj-1234	27	53	by	by	ADP
cuesj-1234	27	54	a	a	DET
cuesj-1234	27	55	2,2	2,2	NUM
cuesj-1234	27	56	-	-	ADJ
cuesj-1234	27	57	dimethylbutyrate	dimethylbutyrate	ADJ
cuesj-1234	27	58	ester	ester	NOUN
cuesj-1234	27	59	group	group	NOUN
cuesj-1234	27	60	as	as	SCONJ
cuesj-1234	27	61	shown	show	VERB
cuesj-1234	27	62	in	in	ADP
cuesj-1234	27	63	figure	figure	NOUN
cuesj-1234	27	64	3	3	NUM
cuesj-1234	27	65	.	.	PUNCT
cuesj-1234	28	1	physiologically	physiologically	ADV
cuesj-1234	28	2	,	,	PUNCT
cuesj-1234	28	3	simvastatin	simvastatin	PROPN
cuesj-1234	28	4	has	have	VERB
cuesj-1234	28	5	a	a	DET
cuesj-1234	28	6	role	role	NOUN
cuesj-1234	28	7	as	as	ADP
cuesj-1234	28	8	an	an	DET
cuesj-1234	28	9	hmg	hmg	NOUN
cuesj-1234	28	10	-	-	PUNCT
cuesj-1234	28	11	coa	coa	NOUN
cuesj-1234	28	12	inhibitor	inhibitor	NOUN
cuesj-1234	28	13	,	,	PUNCT
cuesj-1234	28	14	alf	alf	NOUN
cuesj-1234	28	15	endopeptidase	endopeptidase	ADJ
cuesj-1234	28	16	inhibitor	inhibitor	NOUN
cuesj-1234	28	17	,	,	PUNCT
cuesj-1234	28	18	a	a	DET
cuesj-1234	28	19	geroprotector	geroprotector	NOUN
cuesj-1234	28	20	,	,	PUNCT
cuesj-1234	28	21	and	and	CCONJ
cuesj-1234	28	22	a	a	DET
cuesj-1234	28	23	ferroptosis	ferroptosis	NOUN
cuesj-1234	28	24	inducer	inducer	NOUN
cuesj-1234	28	25	.	.	PUNCT
cuesj-1234	29	1	there	there	PRON
cuesj-1234	29	2	are	be	VERB
cuesj-1234	29	3	multiple	multiple	ADJ
cuesj-1234	29	4	chemical	chemical	ADJ
cuesj-1234	29	5	classes	class	NOUN
cuesj-1234	29	6	that	that	SCONJ
cuesj-1234	29	7	simvastatin	simvastatin	NOUN
cuesj-1234	29	8	belongs	belong	VERB
cuesj-1234	29	9	to	to	ADP
cuesj-1234	29	10	:	:	PUNCT
cuesj-1234	29	11	semi	semi	ADJ
cuesj-1234	29	12	-	-	ADJ
cuesj-1234	29	13	synthetic	synthetic	ADJ
cuesj-1234	29	14	statin	statin	NOUN
cuesj-1234	29	15	,	,	PUNCT
cuesj-1234	29	16	as	as	ADV
cuesj-1234	29	17	well	well	ADV
cuesj-1234	29	18	as	as	ADP
cuesj-1234	29	19	a	a	DET
cuesj-1234	29	20	fatty	fatty	NOUN
cuesj-1234	29	21	acid	acid	NOUN
cuesj-1234	29	22	ester	ester	NOUN
cuesj-1234	29	23	and	and	CCONJ
cuesj-1234	29	24	a	a	DET
cuesj-1234	29	25	delta	delta	NOUN
cuesj-1234	29	26	-	-	PUNCT
cuesj-1234	29	27	lactone.[9	lactone.[9	NOUN
cuesj-1234	29	28	]	]	PUNCT
cuesj-1234	29	29	it	it	PRON
cuesj-1234	29	30	is	be	AUX
cuesj-1234	29	31	a	a	DET
cuesj-1234	29	32	bcs	bcs	NOUN
cuesj-1234	29	33	class	class	NOUN
cuesj-1234	29	34	ii	ii	NOUN
cuesj-1234	29	35	drug	drug	NOUN
cuesj-1234	29	36	,	,	PUNCT
cuesj-1234	29	37	which	which	PRON
cuesj-1234	29	38	,	,	PUNCT
cuesj-1234	29	39	as	as	SCONJ
cuesj-1234	29	40	mentioned	mention	VERB
cuesj-1234	29	41	previously	previously	ADV
cuesj-1234	29	42	,	,	PUNCT
cuesj-1234	29	43	means	mean	VERB
cuesj-1234	29	44	it	it	PRON
cuesj-1234	29	45	has	have	VERB
cuesj-1234	29	46	low	low	ADJ
cuesj-1234	29	47	solubility	solubility	NOUN
cuesj-1234	29	48	in	in	ADP
cuesj-1234	29	49	water	water	NOUN
cuesj-1234	29	50	but	but	CCONJ
cuesj-1234	29	51	high	high	ADJ
cuesj-1234	29	52	absorption	absorption	NOUN
cuesj-1234	29	53	.	.	PUNCT
cuesj-1234	30	1	the	the	DET
cuesj-1234	30	2	solubility	solubility	NOUN
cuesj-1234	30	3	is	be	AUX
cuesj-1234	30	4	0.012	0.012	NUM
cuesj-1234	30	5	g	g	PROPN
cuesj-1234	30	6	/	/	SYM
cuesj-1234	30	7	l	l	NOUN
cuesj-1234	30	8	,	,	PUNCT
cuesj-1234	30	9	or	or	CCONJ
cuesj-1234	30	10	0.012	0.012	NUM
cuesj-1234	30	11	mg	mg	NUM
cuesj-1234	30	12	/	/	SYM
cuesj-1234	30	13	ml	ml	NOUN
cuesj-1234	30	14	,	,	PUNCT
cuesj-1234	30	15	which	which	PRON
cuesj-1234	30	16	officially	officially	ADV
cuesj-1234	30	17	categorizes	categorize	VERB
cuesj-1234	30	18	it	it	PRON
cuesj-1234	30	19	as	as	ADP
cuesj-1234	30	20	insoluble	insoluble	ADJ
cuesj-1234	30	21	in	in	ADP
cuesj-1234	30	22	water	water	NOUN
cuesj-1234	30	23	,	,	PUNCT
cuesj-1234	30	24	according	accord	VERB
cuesj-1234	30	25	to	to	ADP
cuesj-1234	30	26	the	the	DET
cuesj-1234	30	27	united	united	PROPN
cuesj-1234	30	28	states	states	PROPN
cuesj-1234	30	29	pharmacopeia	pharmacopeia	PROPN
cuesj-1234	30	30	.	.	PUNCT
cuesj-1234	31	1	the	the	DET
cuesj-1234	31	2	usp	usp	PROPN
cuesj-1234	31	3	requires	require	VERB
cuesj-1234	31	4	a	a	DET
cuesj-1234	31	5	drug	drug	NOUN
cuesj-1234	31	6	to	to	PART
cuesj-1234	31	7	have	have	VERB
cuesj-1234	31	8	a	a	DET
cuesj-1234	31	9	solubility	solubility	NOUN
cuesj-1234	31	10	of	of	ADP
cuesj-1234	31	11	33	33	NUM
cuesj-1234	31	12	mg	mg	NOUN
cuesj-1234	31	13	/	/	SYM
cuesj-1234	31	14	ml	ml	NOUN
cuesj-1234	31	15	or	or	CCONJ
cuesj-1234	31	16	more	more	ADJ
cuesj-1234	31	17	to	to	PART
cuesj-1234	31	18	be	be	AUX
cuesj-1234	31	19	considered	consider	VERB
cuesj-1234	31	20	soluble	soluble	ADJ
cuesj-1234	31	21	,	,	PUNCT
cuesj-1234	31	22	as	as	SCONJ
cuesj-1234	31	23	shown	show	VERB
cuesj-1234	31	24	in	in	ADP
cuesj-1234	31	25	figure	figure	NOUN
cuesj-1234	31	26	2	2	NUM
cuesj-1234	31	27	.	.	PUNCT
cuesj-1234	32	1	this	this	PRON
cuesj-1234	32	2	is	be	AUX
cuesj-1234	32	3	the	the	DET
cuesj-1234	32	4	problem	problem	NOUN
cuesj-1234	32	5	that	that	SCONJ
cuesj-1234	32	6	this	this	DET
cuesj-1234	32	7	experiment	experiment	NOUN
cuesj-1234	32	8	will	will	AUX
cuesj-1234	32	9	try	try	VERB
cuesj-1234	32	10	to	to	PART
cuesj-1234	32	11	remedy	remedy	VERB
cuesj-1234	32	12	.	.	PUNCT
cuesj-1234	33	1	simvastatin	simvastatin	PROPN
cuesj-1234	33	2	is	be	AUX
cuesj-1234	33	3	,	,	PUNCT
cuesj-1234	33	4	however	however	ADV
cuesj-1234	33	5	,	,	PUNCT
cuesj-1234	33	6	freely	freely	ADV
cuesj-1234	33	7	soluble	soluble	ADJ
cuesj-1234	33	8	in	in	ADP
cuesj-1234	33	9	ethanol	ethanol	NOUN
cuesj-1234	33	10	,	,	PUNCT
cuesj-1234	33	11	methanol	methanol	NOUN
cuesj-1234	33	12	,	,	PUNCT
cuesj-1234	33	13	and	and	CCONJ
cuesj-1234	33	14	chloroform.[10	chloroform.[10	X
cuesj-1234	33	15	]	]	X
cuesj-1234	33	16	it	it	PRON
cuesj-1234	33	17	has	have	VERB
cuesj-1234	33	18	a	a	DET
cuesj-1234	33	19	melting	melting	NOUN
cuesj-1234	33	20	point	point	NOUN
cuesj-1234	33	21	of	of	ADP
cuesj-1234	33	22	135–138	135–138	NUM
cuesj-1234	33	23	°	°	PROPN
cuesj-1234	33	24	c	c	NOUN
cuesj-1234	33	25	.	.	PUNCT
cuesj-1234	34	1	the	the	DET
cuesj-1234	34	2	log	log	NOUN
cuesj-1234	34	3	kow	kow	PROPN
cuesj-1234	34	4	,	,	PUNCT
cuesj-1234	34	5	or	or	CCONJ
cuesj-1234	34	6	octanol	octanol	NOUN
cuesj-1234	34	7	-	-	PUNCT
cuesj-1234	34	8	water	water	NOUN
cuesj-1234	34	9	partition	partition	NOUN
cuesj-1234	34	10	coefficient	coefficient	NOUN
cuesj-1234	34	11	,	,	PUNCT
cuesj-1234	34	12	is	be	AUX
cuesj-1234	34	13	4.68.[11	4.68.[11	PROPN
cuesj-1234	34	14	]	]	PUNCT
cuesj-1234	34	15	simvastatin	simvastatin	NOUN
cuesj-1234	34	16	is	be	AUX
cuesj-1234	34	17	found	find	VERB
cuesj-1234	34	18	as	as	ADP
cuesj-1234	34	19	a	a	DET
cuesj-1234	34	20	white	white	NOUN
cuesj-1234	34	21	to	to	PART
cuesj-1234	34	22	off	off	ADP
cuesj-1234	34	23	-	-	PUNCT
cuesj-1234	34	24	white	white	ADJ
cuesj-1234	34	25	crystalline	crystalline	NOUN
cuesj-1234	34	26	powder	powder	NOUN
cuesj-1234	34	27	,	,	PUNCT
cuesj-1234	34	28	and	and	CCONJ
cuesj-1234	34	29	it	it	PRON
cuesj-1234	34	30	has	have	VERB
cuesj-1234	34	31	a	a	DET
cuesj-1234	34	32	molecular	molecular	ADJ
cuesj-1234	34	33	weight	weight	NOUN
cuesj-1234	34	34	of	of	ADP
cuesj-1234	34	35	418.57g	418.57g	NOUN
cuesj-1234	34	36	/	/	SYM
cuesj-1234	34	37	mol	mol	PROPN
cuesj-1234	34	38	.	.	PUNCT
cuesj-1234	35	1	it	it	PRON
cuesj-1234	35	2	is	be	AUX
cuesj-1234	35	3	nonhygroscopic.[12	nonhygroscopic.[12	NOUN
cuesj-1234	35	4	]	]	PUNCT
cuesj-1234	35	5	sodium	sodium	NOUN
cuesj-1234	35	6	docusate	docusate	NOUN
cuesj-1234	35	7	is	be	AUX
cuesj-1234	35	8	the	the	DET
cuesj-1234	35	9	common	common	ADJ
cuesj-1234	35	10	pharmaceutical	pharmaceutical	ADJ
cuesj-1234	35	11	and	and	CCONJ
cuesj-1234	35	12	chemical	chemical	NOUN
cuesj-1234	35	13	name	name	NOUN
cuesj-1234	35	14	of	of	ADP
cuesj-1234	35	15	the	the	DET
cuesj-1234	35	16	anion	anion	NOUN
cuesj-1234	35	17	bis	bis	X
cuesj-1234	35	18	(	(	PUNCT
cuesj-1234	35	19	2	2	NUM
cuesj-1234	35	20	-	-	PUNCT
cuesj-1234	35	21	ethylhexyl	ethylhexyl	NOUN
cuesj-1234	35	22	)	)	PUNCT
cuesj-1234	35	23	sulfosuccinate	sulfosuccinate	NOUN
cuesj-1234	35	24	,	,	PUNCT
cuesj-1234	35	25	also	also	ADV
cuesj-1234	35	26	called	call	VERB
cuesj-1234	35	27	dioctyl	dioctyl	NOUN
cuesj-1234	35	28	sulfosuccinate	sulfosuccinate	NOUN
cuesj-1234	35	29	.	.	PUNCT
cuesj-1234	36	1	dioctyl	dioctyl	NOUN
cuesj-1234	36	2	sodium	sodium	PROPN
cuesj-1234	36	3	sulfosuccinate	sulfosuccinate	NOUN
cuesj-1234	36	4	is	be	AUX
cuesj-1234	36	5	used	use	VERB
cuesj-1234	36	6	as	as	ADP
cuesj-1234	36	7	a	a	DET
cuesj-1234	36	8	surfactant	surfactant	NOUN
cuesj-1234	36	9	in	in	ADP
cuesj-1234	36	10	many	many	ADJ
cuesj-1234	36	11	different	different	ADJ
cuesj-1234	36	12	applications	application	NOUN
cuesj-1234	36	13	.	.	PUNCT
cuesj-1234	37	1	it	it	PRON
cuesj-1234	37	2	is	be	AUX
cuesj-1234	37	3	unique	unique	ADJ
cuesj-1234	37	4	in	in	SCONJ
cuesj-1234	37	5	that	that	SCONJ
cuesj-1234	37	6	it	it	PRON
cuesj-1234	37	7	can	can	AUX
cuesj-1234	37	8	form	form	VERB
cuesj-1234	37	9	microemulsions	microemulsion	NOUN
cuesj-1234	37	10	without	without	ADP
cuesj-1234	37	11	the	the	DET
cuesj-1234	37	12	presence	presence	NOUN
cuesj-1234	37	13	of	of	ADP
cuesj-1234	37	14	co	co	NOUN
cuesj-1234	37	15	-	-	NOUN
cuesj-1234	37	16	surfactants	surfactant	NOUN
cuesj-1234	37	17	,	,	PUNCT
cuesj-1234	37	18	and	and	CCONJ
cuesj-1234	37	19	it	it	PRON
cuesj-1234	37	20	has	have	VERB
cuesj-1234	37	21	varied	vary	VERB
cuesj-1234	37	22	aqueous	aqueous	ADJ
cuesj-1234	37	23	-	-	PUNCT
cuesj-1234	37	24	phase	phase	NOUN
cuesj-1234	37	25	actions	action	NOUN
cuesj-1234	37	26	,	,	PUNCT
cuesj-1234	37	27	which	which	PRON
cuesj-1234	37	28	include	include	VERB
cuesj-1234	37	29	several	several	ADJ
cuesj-1234	37	30	liquid	liquid	ADJ
cuesj-1234	37	31	crystalline	crystalline	NOUN
cuesj-1234	37	32	phases.[14	phases.[14	PROPN
cuesj-1234	37	33	]	]	PUNCT
cuesj-1234	37	34	the	the	DET
cuesj-1234	37	35	compound	compound	NOUN
cuesj-1234	37	36	is	be	AUX
cuesj-1234	37	37	a	a	DET
cuesj-1234	37	38	white	white	ADJ
cuesj-1234	37	39	,	,	PUNCT
cuesj-1234	37	40	wax	wax	NOUN
cuesj-1234	37	41	-	-	PUNCT
cuesj-1234	37	42	like	like	ADJ
cuesj-1234	37	43	,	,	PUNCT
cuesj-1234	37	44	plastic	plastic	NOUN
cuesj-1234	37	45	solid	solid	ADJ
cuesj-1234	37	46	and	and	CCONJ
cuesj-1234	37	47	has	have	VERB
cuesj-1234	37	48	an	an	DET
cuesj-1234	37	49	odor	odor	NOUN
cuesj-1234	37	50	reminiscent	reminiscent	ADJ
cuesj-1234	37	51	of	of	ADP
cuesj-1234	37	52	octanol	octanol	NOUN
cuesj-1234	37	53	.	.	PUNCT
cuesj-1234	38	1	it	it	PRON
cuesj-1234	38	2	starts	start	VERB
cuesj-1234	38	3	to	to	PART
cuesj-1234	38	4	degrade	degrade	VERB
cuesj-1234	38	5	at	at	ADP
cuesj-1234	38	6	220	220	NUM
cuesj-1234	38	7	°	°	NOUN
cuesj-1234	38	8	c	c	NOUN
cuesj-1234	38	9	.	.	PUNCT
cuesj-1234	39	1	the	the	DET
cuesj-1234	39	2	solubility	solubility	NOUN
cuesj-1234	39	3	of	of	ADP
cuesj-1234	39	4	dioctyl	dioctyl	NOUN
cuesj-1234	39	5	sodium	sodium	NOUN
cuesj-1234	39	6	sulfosuccinate	sulfosuccinate	NOUN
cuesj-1234	39	7	in	in	ADP
cuesj-1234	39	8	water	water	NOUN
cuesj-1234	39	9	is	be	AUX
cuesj-1234	39	10	14	14	NUM
cuesj-1234	39	11	g	g	NOUN
cuesj-1234	39	12	/	/	SYM
cuesj-1234	39	13	l	l	NOUN
cuesj-1234	39	14	at	at	ADP
cuesj-1234	39	15	25	25	NUM
cuesj-1234	39	16	°	°	NOUN
cuesj-1234	39	17	c.[15	c.[15	NOUN
cuesj-1234	39	18	]	]	X
cuesj-1234	39	19	solubility	solubility	NOUN
cuesj-1234	39	20	of	of	ADP
cuesj-1234	39	21	docusate	docusate	NOUN
cuesj-1234	39	22	is	be	AUX
cuesj-1234	39	23	better	well	ADJ
cuesj-1234	39	24	in	in	ADP
cuesj-1234	39	25	solvents	solvent	NOUN
cuesj-1234	39	26	with	with	ADP
cuesj-1234	39	27	a	a	DET
cuesj-1234	39	28	lower	low	ADJ
cuesj-1234	39	29	polarity	polarity	NOUN
cuesj-1234	39	30	,	,	PUNCT
cuesj-1234	39	31	with	with	ADP
cuesj-1234	39	32	ratios	ratio	NOUN
cuesj-1234	39	33	of	of	ADP
cuesj-1234	39	34	1:30	1:30	NUM
cuesj-1234	39	35	in	in	ADP
cuesj-1234	39	36	ethanol	ethanol	NOUN
cuesj-1234	39	37	,	,	PUNCT
cuesj-1234	39	38	1:1	1:1	NUM
cuesj-1234	39	39	in	in	ADP
cuesj-1234	39	40	diethyl	diethyl	NOUN
cuesj-1234	39	41	ether	ether	NOUN
cuesj-1234	39	42	and	and	CCONJ
cuesj-1234	39	43	chloroform	chloroform	NOUN
cuesj-1234	39	44	,	,	PUNCT
cuesj-1234	39	45	and	and	CCONJ
cuesj-1234	39	46	practically	practically	ADV
cuesj-1234	39	47	unlimited	unlimited	ADJ
cuesj-1234	39	48	in	in	ADP
cuesj-1234	39	49	petroleum	petroleum	NOUN
cuesj-1234	39	50	ether	ether	NOUN
cuesj-1234	39	51	,	,	PUNCT
cuesj-1234	39	52	all	all	PRON
cuesj-1234	39	53	at	at	ADP
cuesj-1234	39	54	room	room	NOUN
cuesj-1234	39	55	temperature	temperature	NOUN
cuesj-1234	39	56	(	(	PUNCT
cuesj-1234	39	57	25	25	NUM
cuesj-1234	39	58	°	°	PROPN
cuesj-1234	39	59	c	c	NOUN
cuesj-1234	39	60	)	)	PUNCT
cuesj-1234	39	61	.	.	PUNCT
cuesj-1234	40	1	in	in	ADP
cuesj-1234	40	2	general	general	ADJ
cuesj-1234	40	3	,	,	PUNCT
cuesj-1234	40	4	its	its	PRON
cuesj-1234	40	5	uses	use	NOUN
cuesj-1234	40	6	include	include	VERB
cuesj-1234	40	7	a	a	DET
cuesj-1234	40	8	wetting	wet	VERB
cuesj-1234	40	9	agent	agent	NOUN
cuesj-1234	40	10	,	,	PUNCT
cuesj-1234	40	11	anionic	anionic	ADJ
cuesj-1234	40	12	surfactant	surfactant	NOUN
cuesj-1234	40	13	,	,	PUNCT
cuesj-1234	40	14	solubilizer	solubilizer	NOUN
cuesj-1234	40	15	,	,	PUNCT
cuesj-1234	40	16	and	and	CCONJ
cuesj-1234	40	17	fecal	fecal	ADJ
cuesj-1234	40	18	softener.[16	softener.[16	PROPN
cuesj-1234	40	19	]	]	PUNCT
cuesj-1234	40	20	the	the	DET
cuesj-1234	40	21	chemical	chemical	NOUN
cuesj-1234	40	22	structure	structure	NOUN
cuesj-1234	40	23	of	of	ADP
cuesj-1234	40	24	sodium	sodium	NOUN
cuesj-1234	40	25	docusate	docusate	NOUN
cuesj-1234	40	26	is	be	AUX
cuesj-1234	40	27	shown	show	VERB
cuesj-1234	40	28	in	in	ADP
cuesj-1234	40	29	figure	figure	NOUN
cuesj-1234	40	30	4	4	NUM
cuesj-1234	40	31	.	.	PUNCT
cuesj-1234	40	32	sodium	sodium	NOUN
cuesj-1234	40	33	docusate	docusate	NOUN
cuesj-1234	40	34	has	have	VERB
cuesj-1234	40	35	anionic	anionic	ADJ
cuesj-1234	40	36	surfactant	surfactant	NOUN
cuesj-1234	40	37	properties	property	NOUN
cuesj-1234	40	38	that	that	PRON
cuesj-1234	40	39	are	be	AUX
cuesj-1234	40	40	useful	useful	ADJ
cuesj-1234	40	41	in	in	ADP
cuesj-1234	40	42	solid	solid	ADJ
cuesj-1234	40	43	dispersion	dispersion	NOUN
cuesj-1234	40	44	and	and	CCONJ
cuesj-1234	40	45	that	that	PRON
cuesj-1234	40	46	enhance	enhance	VERB
cuesj-1234	40	47	the	the	DET
cuesj-1234	40	48	wettability	wettability	NOUN
cuesj-1234	40	49	of	of	ADP
cuesj-1234	40	50	the	the	DET
cuesj-1234	40	51	molecules	molecule	NOUN
cuesj-1234	40	52	they	they	PRON
cuesj-1234	40	53	attach	attach	VERB
cuesj-1234	40	54	to	to	ADP
cuesj-1234	40	55	,	,	PUNCT
cuesj-1234	40	56	and	and	CCONJ
cuesj-1234	40	57	the	the	DET
cuesj-1234	40	58	more	more	ADJ
cuesj-1234	40	59	solvation	solvation	NOUN
cuesj-1234	40	60	that	that	PRON
cuesj-1234	40	61	occurs	occur	VERB
cuesj-1234	40	62	,	,	PUNCT
cuesj-1234	40	63	the	the	DET
cuesj-1234	40	64	more	more	ADV
cuesj-1234	40	65	soluble	soluble	ADJ
cuesj-1234	40	66	the	the	DET
cuesj-1234	40	67	compound	compound	NOUN
cuesj-1234	40	68	becomes.[17	becomes.[17	PROPN
cuesj-1234	40	69	]	]	PUNCT
cuesj-1234	40	70	surfactants	surfactant	NOUN
cuesj-1234	40	71	in	in	ADP
cuesj-1234	40	72	general	general	ADJ
cuesj-1234	40	73	form	form	NOUN
cuesj-1234	40	74	micelles	micelle	NOUN
cuesj-1234	40	75	;	;	PUNCT
cuesj-1234	40	76	these	these	DET
cuesj-1234	40	77	micelles	micelle	NOUN
cuesj-1234	40	78	form	form	VERB
cuesj-1234	40	79	at	at	ADP
cuesj-1234	40	80	a	a	DET
cuesj-1234	40	81	certain	certain	ADJ
cuesj-1234	40	82	concentration	concentration	NOUN
cuesj-1234	40	83	,	,	PUNCT
cuesj-1234	40	84	called	call	VERB
cuesj-1234	40	85	the	the	DET
cuesj-1234	40	86	critical	critical	ADJ
cuesj-1234	40	87	micelle	micelle	NOUN
cuesj-1234	40	88	concentration	concentration	NOUN
cuesj-1234	40	89	(	(	PUNCT
cuesj-1234	40	90	cmc	cmc	NOUN
cuesj-1234	40	91	)	)	PUNCT
cuesj-1234	40	92	,	,	PUNCT
cuesj-1234	40	93	and	and	CCONJ
cuesj-1234	40	94	work	work	VERB
cuesj-1234	40	95	to	to	PART
cuesj-1234	40	96	solubilize	solubilize	VERB
cuesj-1234	40	97	insoluble	insoluble	ADJ
cuesj-1234	40	98	products	product	NOUN
cuesj-1234	40	99	,	,	PUNCT
cuesj-1234	40	100	with	with	ADP
cuesj-1234	40	101	an	an	DET
cuesj-1234	40	102	increase	increase	NOUN
cuesj-1234	40	103	in	in	ADP
cuesj-1234	40	104	the	the	DET
cuesj-1234	40	105	amount	amount	NOUN
cuesj-1234	40	106	of	of	ADP
cuesj-1234	40	107	surfactant	surfactant	NOUN
cuesj-1234	40	108	correlating	correlate	VERB
cuesj-1234	40	109	to	to	ADP
cuesj-1234	40	110	an	an	DET
cuesj-1234	40	111	increase	increase	NOUN
cuesj-1234	40	112	in	in	ADP
cuesj-1234	40	113	solvation	solvation	NOUN
cuesj-1234	40	114	and	and	CCONJ
cuesj-1234	40	115	solubilization.[18	solubilization.[18	NOUN
cuesj-1234	40	116	]	]	X
cuesj-1234	40	117	the	the	DET
cuesj-1234	40	118	cmc	cmc	NOUN
cuesj-1234	40	119	depends	depend	VERB
cuesj-1234	40	120	on	on	ADP
cuesj-1234	40	121	the	the	DET
cuesj-1234	40	122	molecular	molecular	ADJ
cuesj-1234	40	123	and	and	CCONJ
cuesj-1234	40	124	chemical	chemical	NOUN
cuesj-1234	40	125	properties	property	NOUN
cuesj-1234	40	126	of	of	ADP
cuesj-1234	40	127	the	the	DET
cuesj-1234	40	128	surfactant	surfactant	NOUN
cuesj-1234	40	129	,	,	PUNCT
cuesj-1234	40	130	such	such	ADJ
cuesj-1234	40	131	as	as	ADP
cuesj-1234	40	132	polarity	polarity	NOUN
cuesj-1234	40	133	and	and	CCONJ
cuesj-1234	40	134	charge	charge	NOUN
cuesj-1234	40	135	.	.	PUNCT
cuesj-1234	41	1	micelles	micelle	NOUN
cuesj-1234	41	2	are	be	AUX
cuesj-1234	41	3	normally	normally	ADV
cuesj-1234	41	4	made	make	VERB
cuesj-1234	41	5	up	up	ADP
cuesj-1234	41	6	of	of	ADP
cuesj-1234	41	7	amphiphilic	amphiphilic	ADJ
cuesj-1234	41	8	polymers	polymer	NOUN
cuesj-1234	41	9	which	which	PRON
cuesj-1234	41	10	mean	mean	VERB
cuesj-1234	41	11	they	they	PRON
cuesj-1234	41	12	have	have	VERB
cuesj-1234	41	13	both	both	CCONJ
cuesj-1234	41	14	hydrophilic	hydrophilic	ADJ
cuesj-1234	41	15	and	and	CCONJ
cuesj-1234	41	16	hydrophobic	hydrophobic	NOUN
cuesj-1234	41	17	parts	part	NOUN
cuesj-1234	41	18	.	.	PUNCT
cuesj-1234	42	1	the	the	DET
cuesj-1234	42	2	best	good	ADJ
cuesj-1234	42	3	size	size	NOUN
cuesj-1234	42	4	for	for	ADP
cuesj-1234	42	5	micelles	micelle	NOUN
cuesj-1234	42	6	is	be	AUX
cuesj-1234	42	7	10–100	10–100	PROPN
cuesj-1234	42	8	nm	nm	NOUN
cuesj-1234	42	9	,	,	PUNCT
cuesj-1234	42	10	and	and	CCONJ
cuesj-1234	42	11	in	in	ADP
cuesj-1234	42	12	aqueous	aqueous	ADJ
cuesj-1234	42	13	solutions	solution	NOUN
cuesj-1234	42	14	,	,	PUNCT
cuesj-1234	42	15	they	they	PRON
cuesj-1234	42	16	spontaneously	spontaneously	ADV
cuesj-1234	42	17	assemble	assemble	VERB
cuesj-1234	42	18	to	to	PART
cuesj-1234	42	19	form	form	VERB
cuesj-1234	42	20	sphereor	sphereor	NOUN
cuesj-1234	42	21	sphere	sphere	NOUN
cuesj-1234	42	22	-	-	PUNCT
cuesj-1234	42	23	like	like	ADJ
cuesj-1234	42	24	shapes	shape	NOUN
cuesj-1234	42	25	,	,	PUNCT
cuesj-1234	42	26	with	with	ADP
cuesj-1234	42	27	a	a	DET
cuesj-1234	42	28	hydrophobic	hydrophobic	NOUN
cuesj-1234	42	29	core	core	NOUN
cuesj-1234	42	30	and	and	CCONJ
cuesj-1234	42	31	hydrophilic	hydrophilic	ADJ
cuesj-1234	42	32	external	external	ADJ
cuesj-1234	42	33	shell	shell	NOUN
cuesj-1234	42	34	.	.	PUNCT
cuesj-1234	43	1	due	due	ADP
cuesj-1234	43	2	to	to	ADP
cuesj-1234	43	3	these	these	DET
cuesj-1234	43	4	properties	property	NOUN
cuesj-1234	43	5	,	,	PUNCT
cuesj-1234	43	6	simvastatin	simvastatin	NOUN
cuesj-1234	43	7	,	,	PUNCT
cuesj-1234	43	8	or	or	CCONJ
cuesj-1234	43	9	other	other	ADJ
cuesj-1234	43	10	drugs	drug	NOUN
cuesj-1234	43	11	with	with	ADP
cuesj-1234	43	12	low	low	ADJ
cuesj-1234	43	13	water	water	NOUN
cuesj-1234	43	14	solubility	solubility	NOUN
cuesj-1234	43	15	,	,	PUNCT
cuesj-1234	43	16	can	can	AUX
cuesj-1234	43	17	dissolve	dissolve	VERB
cuesj-1234	43	18	in	in	ADP
cuesj-1234	43	19	micelles.[19	micelles.[19	NOUN
cuesj-1234	43	20	]	]	PUNCT
cuesj-1234	43	21	isoleucine	isoleucine	NOUN
cuesj-1234	43	22	is	be	AUX
cuesj-1234	43	23	one	one	NUM
cuesj-1234	43	24	of	of	ADP
cuesj-1234	43	25	the	the	DET
cuesj-1234	43	26	essential	essential	ADJ
cuesj-1234	43	27	amino	amino	NOUN
cuesj-1234	43	28	acids	acid	NOUN
cuesj-1234	43	29	.	.	PUNCT
cuesj-1234	44	1	isoleucine	isoleucine	NOUN
cuesj-1234	44	2	is	be	AUX
cuesj-1234	44	3	required	require	VERB
cuesj-1234	44	4	for	for	ADP
cuesj-1234	44	5	hemoglobin	hemoglobin	NOUN
cuesj-1234	44	6	formation	formation	NOUN
cuesj-1234	44	7	,	,	PUNCT
cuesj-1234	44	8	stabilization	stabilization	NOUN
cuesj-1234	44	9	,	,	PUNCT
cuesj-1234	44	10	and	and	CCONJ
cuesj-1234	44	11	figure	figure	VERB
cuesj-1234	44	12	2	2	NUM
cuesj-1234	44	13	:	:	PUNCT
cuesj-1234	44	14	solubility	solubility	NOUN
cuesj-1234	44	15	definition[7	definition[7	PROPN
cuesj-1234	44	16	]	]	PUNCT
cuesj-1234	44	17	figure	figure	NOUN
cuesj-1234	44	18	1	1	NUM
cuesj-1234	44	19	:	:	PUNCT
cuesj-1234	44	20	bcs	bcs	NOUN
cuesj-1234	44	21	categories[5	categories[5	PROPN
cuesj-1234	44	22	]	]	PUNCT
cuesj-1234	44	23	figure	figure	NOUN
cuesj-1234	44	24	3	3	NUM
cuesj-1234	44	25	:	:	PUNCT
cuesj-1234	44	26	simvastatin	simvastatin	PROPN
cuesj-1234	44	27	structure[13	structure[13	PROPN
cuesj-1234	44	28	]	]	X
cuesj-1234	44	29	al	al	PROPN
cuesj-1234	44	30	-	-	PUNCT
cuesj-1234	44	31	jumaili	jumaili	PROPN
cuesj-1234	44	32	,	,	PUNCT
cuesj-1234	44	33	et	et	PROPN
cuesj-1234	44	34	al	al	PROPN
cuesj-1234	44	35	.	.	PROPN
cuesj-1234	44	36	:	:	PUNCT
cuesj-1234	44	37	enhancing	enhance	VERB
cuesj-1234	44	38	solubility	solubility	NOUN
cuesj-1234	44	39	of	of	ADP
cuesj-1234	44	40	simvastatin	simvastatin	NOUN
cuesj-1234	44	41	with	with	ADP
cuesj-1234	44	42	l	l	NOUN
cuesj-1234	44	43	-	-	NOUN
cuesj-1234	44	44	isoleucine	isoleucine	ADJ
cuesj-1234	44	45	and	and	CCONJ
cuesj-1234	44	46	sodium	sodium	NOUN
cuesj-1234	44	47	docusate	docusate	NOUN
cuesj-1234	44	48	28	28	NUM
cuesj-1234	44	49	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	44	50	cuesj	cuesj	NOUN
cuesj-1234	44	51	2025	2025	NUM
cuesj-1234	44	52	,	,	PUNCT
cuesj-1234	44	53	9	9	NUM
cuesj-1234	44	54	(	(	PUNCT
cuesj-1234	44	55	2	2	NUM
cuesj-1234	44	56	):	):	PUNCT
cuesj-1234	44	57	26	26	NUM
cuesj-1234	44	58	-	-	SYM
cuesj-1234	44	59	32	32	NUM
cuesj-1234	44	60	regulation	regulation	NOUN
cuesj-1234	44	61	of	of	ADP
cuesj-1234	44	62	blood	blood	NOUN
cuesj-1234	44	63	sugar	sugar	NOUN
cuesj-1234	44	64	and	and	CCONJ
cuesj-1234	44	65	energy	energy	NOUN
cuesj-1234	44	66	levels	level	NOUN
cuesj-1234	44	67	.	.	PUNCT
cuesj-1234	45	1	it	it	PRON
cuesj-1234	45	2	is	be	AUX
cuesj-1234	45	3	one	one	NUM
cuesj-1234	45	4	of	of	ADP
cuesj-1234	45	5	the	the	DET
cuesj-1234	45	6	three	three	NUM
cuesj-1234	45	7	branched	branch	VERB
cuesj-1234	45	8	-	-	PUNCT
cuesj-1234	45	9	chain	chain	NOUN
cuesj-1234	45	10	amino	amino	NOUN
cuesj-1234	45	11	acids	acid	NOUN
cuesj-1234	45	12	,	,	PUNCT
cuesj-1234	45	13	and	and	CCONJ
cuesj-1234	45	14	these	these	DET
cuesj-1234	45	15	amino	amino	ADJ
cuesj-1234	45	16	acids	acid	NOUN
cuesj-1234	45	17	increase	increase	NOUN
cuesj-1234	45	18	endurance	endurance	NOUN
cuesj-1234	45	19	,	,	PUNCT
cuesj-1234	45	20	improve	improve	VERB
cuesj-1234	45	21	energy	energy	NOUN
cuesj-1234	45	22	,	,	PUNCT
cuesj-1234	45	23	and	and	CCONJ
cuesj-1234	45	24	help	help	VERB
cuesj-1234	45	25	in	in	ADP
cuesj-1234	45	26	muscle	muscle	NOUN
cuesj-1234	45	27	tissue	tissue	NOUN
cuesj-1234	45	28	repair	repair	NOUN
cuesj-1234	45	29	.	.	PUNCT
cuesj-1234	46	1	isoleucine	isoleucine	PROPN
cuesj-1234	46	2	also	also	ADV
cuesj-1234	46	3	has	have	VERB
cuesj-1234	46	4	an	an	DET
cuesj-1234	46	5	important	important	ADJ
cuesj-1234	46	6	role	role	NOUN
cuesj-1234	46	7	in	in	ADP
cuesj-1234	46	8	immunity.[21	immunity.[21	PROPN
cuesj-1234	46	9	]	]	PUNCT
cuesj-1234	46	10	isoleucine	isoleucine	NOUN
cuesj-1234	46	11	is	be	AUX
cuesj-1234	46	12	found	find	VERB
cuesj-1234	46	13	as	as	ADP
cuesj-1234	46	14	a	a	DET
cuesj-1234	46	15	white	white	NOUN
cuesj-1234	46	16	to	to	PART
cuesj-1234	46	17	off	off	ADP
cuesj-1234	46	18	-	-	PUNCT
cuesj-1234	46	19	white	white	ADJ
cuesj-1234	46	20	powder	powder	NOUN
cuesj-1234	46	21	with	with	ADP
cuesj-1234	46	22	a	a	DET
cuesj-1234	46	23	sweet	sweet	ADJ
cuesj-1234	46	24	odor.[22	odor.[22	NOUN
cuesj-1234	46	25	]	]	PUNCT
cuesj-1234	46	26	the	the	DET
cuesj-1234	46	27	solubility	solubility	NOUN
cuesj-1234	46	28	of	of	ADP
cuesj-1234	46	29	isoleucine	isoleucine	NOUN
cuesj-1234	46	30	is	be	AUX
cuesj-1234	46	31	34.4	34.4	NUM
cuesj-1234	46	32	g	g	NOUN
cuesj-1234	46	33	/	/	SYM
cuesj-1234	46	34	l	l	NOUN
cuesj-1234	46	35	,	,	PUNCT
cuesj-1234	46	36	with	with	ADP
cuesj-1234	46	37	a	a	DET
cuesj-1234	46	38	molecular	molecular	ADJ
cuesj-1234	46	39	weight	weight	NOUN
cuesj-1234	46	40	of	of	ADP
cuesj-1234	46	41	131	131	NUM
cuesj-1234	46	42	g	g	NOUN
cuesj-1234	46	43	/	/	SYM
cuesj-1234	46	44	mol	mol	NOUN
cuesj-1234	46	45	.	.	PUNCT
cuesj-1234	47	1	its	its	PRON
cuesj-1234	47	2	boiling	boiling	NOUN
cuesj-1234	47	3	point	point	NOUN
cuesj-1234	47	4	is	be	AUX
cuesj-1234	47	5	168	168	NUM
cuesj-1234	47	6	–	–	PUNCT
cuesj-1234	47	7	170	170	NUM
cuesj-1234	47	8	°	°	NOUN
cuesj-1234	47	9	c	c	NOUN
cuesj-1234	47	10	,	,	PUNCT
cuesj-1234	47	11	with	with	ADP
cuesj-1234	47	12	two	two	NUM
cuesj-1234	47	13	pka	pka	PROPN
cuesj-1234	47	14	values	value	NOUN
cuesj-1234	47	15	:	:	PUNCT
cuesj-1234	47	16	2.32	2.32	NUM
cuesj-1234	47	17	and	and	CCONJ
cuesj-1234	47	18	9.76.[23	9.76.[23	PRON
cuesj-1234	47	19	]	]	X
cuesj-1234	47	20	the	the	DET
cuesj-1234	47	21	structure	structure	NOUN
cuesj-1234	47	22	of	of	ADP
cuesj-1234	47	23	l	l	NOUN
cuesj-1234	47	24	-	-	NOUN
cuesj-1234	47	25	isoleucine	isoleucine	NOUN
cuesj-1234	47	26	is	be	AUX
cuesj-1234	47	27	shown	show	VERB
cuesj-1234	47	28	in	in	ADP
cuesj-1234	47	29	figure	figure	NOUN
cuesj-1234	47	30	5	5	NUM
cuesj-1234	47	31	.	.	PUNCT
cuesj-1234	48	1	amino	amino	ADJ
cuesj-1234	48	2	acids	acid	NOUN
cuesj-1234	48	3	have	have	AUX
cuesj-1234	48	4	already	already	ADV
cuesj-1234	48	5	proven	prove	VERB
cuesj-1234	48	6	effective	effective	ADJ
cuesj-1234	48	7	in	in	ADP
cuesj-1234	48	8	enhancing	enhance	VERB
cuesj-1234	48	9	the	the	DET
cuesj-1234	48	10	solubility	solubility	NOUN
cuesj-1234	48	11	of	of	ADP
cuesj-1234	48	12	simvastatin.[24	simvastatin.[24	PROPN
cuesj-1234	48	13	]	]	PUNCT
cuesj-1234	48	14	isoleucine	isoleucine	PROPN
cuesj-1234	48	15	has	have	AUX
cuesj-1234	48	16	,	,	PUNCT
cuesj-1234	48	17	in	in	ADP
cuesj-1234	48	18	previous	previous	ADJ
cuesj-1234	48	19	experiments	experiment	NOUN
cuesj-1234	48	20	,	,	PUNCT
cuesj-1234	48	21	been	be	AUX
cuesj-1234	48	22	used	use	VERB
cuesj-1234	48	23	to	to	PART
cuesj-1234	48	24	improve	improve	VERB
cuesj-1234	48	25	the	the	DET
cuesj-1234	48	26	solubility	solubility	NOUN
cuesj-1234	48	27	of	of	ADP
cuesj-1234	48	28	atorvastatin	atorvastatin	NOUN
cuesj-1234	48	29	with	with	ADP
cuesj-1234	48	30	positive	positive	ADJ
cuesj-1234	48	31	results	result	NOUN
cuesj-1234	48	32	,	,	PUNCT
cuesj-1234	48	33	and	and	CCONJ
cuesj-1234	48	34	here	here	ADV
cuesj-1234	48	35	those	those	DET
cuesj-1234	48	36	properties	property	NOUN
cuesj-1234	48	37	were	be	AUX
cuesj-1234	48	38	shown	show	VERB
cuesj-1234	48	39	to	to	PART
cuesj-1234	48	40	be	be	AUX
cuesj-1234	48	41	even	even	ADV
cuesj-1234	48	42	more	more	ADJ
cuesj-1234	48	43	potent.[25	potent.[25	NOUN
cuesj-1234	48	44	]	]	PUNCT
cuesj-1234	48	45	isoleucine	isoleucine	NOUN
cuesj-1234	48	46	is	be	AUX
cuesj-1234	48	47	also	also	ADV
cuesj-1234	48	48	easily	easily	ADV
cuesj-1234	48	49	available	available	ADJ
cuesj-1234	48	50	,	,	PUNCT
cuesj-1234	48	51	which	which	PRON
cuesj-1234	48	52	makes	make	VERB
cuesj-1234	48	53	it	it	PRON
cuesj-1234	48	54	useful	useful	ADJ
cuesj-1234	48	55	in	in	ADP
cuesj-1234	48	56	solubility	solubility	NOUN
cuesj-1234	48	57	enhancement	enhancement	NOUN
cuesj-1234	48	58	.	.	PUNCT
cuesj-1234	49	1	because	because	SCONJ
cuesj-1234	49	2	both	both	DET
cuesj-1234	49	3	isoleucine	isoleucine	NOUN
cuesj-1234	49	4	and	and	CCONJ
cuesj-1234	49	5	docusate	docusate	NOUN
cuesj-1234	49	6	are	be	AUX
cuesj-1234	49	7	inert	inert	ADJ
cuesj-1234	49	8	and	and	CCONJ
cuesj-1234	49	9	have	have	VERB
cuesj-1234	49	10	minimal	minimal	ADJ
cuesj-1234	49	11	side	side	NOUN
cuesj-1234	49	12	effects	effect	NOUN
cuesj-1234	49	13	,	,	PUNCT
cuesj-1234	49	14	they	they	PRON
cuesj-1234	49	15	are	be	AUX
cuesj-1234	49	16	acceptable	acceptable	ADJ
cuesj-1234	49	17	excipients	excipient	NOUN
cuesj-1234	49	18	to	to	PART
cuesj-1234	49	19	use	use	VERB
cuesj-1234	49	20	for	for	ADP
cuesj-1234	49	21	improving	improve	VERB
cuesj-1234	49	22	solubility	solubility	NOUN
cuesj-1234	49	23	.	.	PUNCT
cuesj-1234	50	1	a	a	DET
cuesj-1234	50	2	solid	solid	ADJ
cuesj-1234	50	3	dispersion	dispersion	NOUN
cuesj-1234	50	4	is	be	AUX
cuesj-1234	50	5	defined	define	VERB
cuesj-1234	50	6	as	as	ADP
cuesj-1234	50	7	a	a	DET
cuesj-1234	50	8	group	group	NOUN
cuesj-1234	50	9	of	of	ADP
cuesj-1234	50	10	solid	solid	ADJ
cuesj-1234	50	11	products	product	NOUN
cuesj-1234	50	12	consisting	consist	VERB
cuesj-1234	50	13	of	of	ADP
cuesj-1234	50	14	a	a	DET
cuesj-1234	50	15	hydrophobic	hydrophobic	NOUN
cuesj-1234	50	16	drug	drug	NOUN
cuesj-1234	50	17	that	that	PRON
cuesj-1234	50	18	is	be	AUX
cuesj-1234	50	19	dispersed	disperse	VERB
cuesj-1234	50	20	in	in	ADP
cuesj-1234	50	21	at	at	ADV
cuesj-1234	50	22	least	least	ADV
cuesj-1234	50	23	one	one	NUM
cuesj-1234	50	24	hydrophilic	hydrophilic	ADJ
cuesj-1234	50	25	carrier	carrier	NOUN
cuesj-1234	50	26	,	,	PUNCT
cuesj-1234	50	27	with	with	ADP
cuesj-1234	50	28	a	a	DET
cuesj-1234	50	29	subsequent	subsequent	ADJ
cuesj-1234	50	30	increase	increase	NOUN
cuesj-1234	50	31	in	in	ADP
cuesj-1234	50	32	surface	surface	NOUN
cuesj-1234	50	33	area	area	NOUN
cuesj-1234	50	34	and	and	CCONJ
cuesj-1234	50	35	thus	thus	ADV
cuesj-1234	50	36	enhanced	enhance	VERB
cuesj-1234	50	37	drug	drug	NOUN
cuesj-1234	50	38	solubility	solubility	NOUN
cuesj-1234	50	39	and	and	CCONJ
cuesj-1234	50	40	dissolution	dissolution	NOUN
cuesj-1234	50	41	rate	rate	NOUN
cuesj-1234	50	42	.	.	PUNCT
cuesj-1234	51	1	there	there	PRON
cuesj-1234	51	2	are	be	VERB
cuesj-1234	51	3	several	several	ADJ
cuesj-1234	51	4	advantages	advantage	NOUN
cuesj-1234	51	5	in	in	ADP
cuesj-1234	51	6	using	use	VERB
cuesj-1234	51	7	solid	solid	ADJ
cuesj-1234	51	8	dispersion	dispersion	NOUN
cuesj-1234	51	9	,	,	PUNCT
cuesj-1234	51	10	such	such	ADJ
cuesj-1234	51	11	as	as	ADP
cuesj-1234	51	12	increased	increase	VERB
cuesj-1234	51	13	wettability	wettability	NOUN
cuesj-1234	51	14	,	,	PUNCT
cuesj-1234	51	15	easier	easy	ADJ
cuesj-1234	51	16	formulation	formulation	NOUN
cuesj-1234	51	17	as	as	ADP
cuesj-1234	51	18	a	a	DET
cuesj-1234	51	19	solid	solid	ADJ
cuesj-1234	51	20	dosage	dosage	NOUN
cuesj-1234	51	21	form	form	NOUN
cuesj-1234	51	22	,	,	PUNCT
cuesj-1234	51	23	and	and	CCONJ
cuesj-1234	51	24	greater	great	ADJ
cuesj-1234	51	25	effectiveness	effectiveness	NOUN
cuesj-1234	51	26	in	in	ADP
cuesj-1234	51	27	dissolution	dissolution	NOUN
cuesj-1234	51	28	when	when	SCONJ
cuesj-1234	51	29	compared	compare	VERB
cuesj-1234	51	30	to	to	ADP
cuesj-1234	51	31	salt	salt	NOUN
cuesj-1234	51	32	preparations	preparation	NOUN
cuesj-1234	51	33	,	,	PUNCT
cuesj-1234	51	34	which	which	PRON
cuesj-1234	51	35	require	require	VERB
cuesj-1234	51	36	an	an	DET
cuesj-1234	51	37	ionized	ionized	ADJ
cuesj-1234	51	38	drug	drug	NOUN
cuesj-1234	51	39	compound.[27	compound.[27	PROPN
cuesj-1234	51	40	]	]	PUNCT
cuesj-1234	51	41	in	in	ADP
cuesj-1234	51	42	addition	addition	NOUN
cuesj-1234	51	43	,	,	PUNCT
cuesj-1234	51	44	one	one	NUM
cuesj-1234	51	45	of	of	ADP
cuesj-1234	51	46	the	the	DET
cuesj-1234	51	47	most	most	ADV
cuesj-1234	51	48	important	important	ADJ
cuesj-1234	51	49	advantages	advantage	NOUN
cuesj-1234	51	50	to	to	ADP
cuesj-1234	51	51	using	use	VERB
cuesj-1234	51	52	solid	solid	ADJ
cuesj-1234	51	53	dispersion	dispersion	NOUN
cuesj-1234	51	54	occurs	occur	VERB
cuesj-1234	51	55	with	with	ADP
cuesj-1234	51	56	the	the	DET
cuesj-1234	51	57	interaction	interaction	NOUN
cuesj-1234	51	58	of	of	ADP
cuesj-1234	51	59	hydrophilic	hydrophilic	ADJ
cuesj-1234	51	60	carriers	carrier	NOUN
cuesj-1234	51	61	with	with	ADP
cuesj-1234	51	62	the	the	DET
cuesj-1234	51	63	drug	drug	NOUN
cuesj-1234	51	64	.	.	PUNCT
cuesj-1234	52	1	this	this	DET
cuesj-1234	52	2	interaction	interaction	NOUN
cuesj-1234	52	3	can	can	AUX
cuesj-1234	52	4	decrease	decrease	VERB
cuesj-1234	52	5	agglomeration	agglomeration	NOUN
cuesj-1234	52	6	and	and	CCONJ
cuesj-1234	52	7	release	release	NOUN
cuesj-1234	52	8	when	when	SCONJ
cuesj-1234	52	9	there	there	PRON
cuesj-1234	52	10	is	be	VERB
cuesj-1234	52	11	supersaturation	supersaturation	NOUN
cuesj-1234	52	12	,	,	PUNCT
cuesj-1234	52	13	which	which	PRON
cuesj-1234	52	14	means	mean	VERB
cuesj-1234	52	15	a	a	DET
cuesj-1234	52	16	more	more	ADV
cuesj-1234	52	17	rapid	rapid	ADJ
cuesj-1234	52	18	absorption	absorption	NOUN
cuesj-1234	52	19	,	,	PUNCT
cuesj-1234	52	20	in	in	ADP
cuesj-1234	52	21	addition	addition	NOUN
cuesj-1234	52	22	to	to	ADP
cuesj-1234	52	23	solubility	solubility	NOUN
cuesj-1234	52	24	,	,	PUNCT
cuesj-1234	52	25	and	and	CCONJ
cuesj-1234	52	26	consequently	consequently	ADV
cuesj-1234	52	27	improved	improve	VERB
cuesj-1234	52	28	bioavailability.[28	bioavailability.[28	PROPN
cuesj-1234	52	29	]	]	PUNCT
cuesj-1234	52	30	solid	solid	ADJ
cuesj-1234	52	31	dispersion	dispersion	NOUN
cuesj-1234	52	32	also	also	ADV
cuesj-1234	52	33	produces	produce	VERB
cuesj-1234	52	34	amorphous	amorphous	ADJ
cuesj-1234	52	35	forms	form	NOUN
cuesj-1234	52	36	of	of	ADP
cuesj-1234	52	37	simvastatin	simvastatin	NOUN
cuesj-1234	52	38	,	,	PUNCT
cuesj-1234	52	39	which	which	PRON
cuesj-1234	52	40	have	have	VERB
cuesj-1234	52	41	a	a	DET
cuesj-1234	52	42	higher	high	ADJ
cuesj-1234	52	43	solubility	solubility	NOUN
cuesj-1234	52	44	than	than	ADP
cuesj-1234	52	45	crystalline	crystalline	NOUN
cuesj-1234	52	46	simvastatin.[29	simvastatin.[29	NOUN
cuesj-1234	52	47	]	]	X
cuesj-1234	52	48	the	the	DET
cuesj-1234	52	49	key	key	ADJ
cuesj-1234	52	50	idea	idea	NOUN
cuesj-1234	52	51	in	in	ADP
cuesj-1234	52	52	solvent	solvent	ADJ
cuesj-1234	52	53	evaporation	evaporation	NOUN
cuesj-1234	52	54	is	be	AUX
cuesj-1234	52	55	that	that	SCONJ
cuesj-1234	52	56	the	the	DET
cuesj-1234	52	57	drug	drug	NOUN
cuesj-1234	52	58	in	in	ADP
cuesj-1234	52	59	question	question	NOUN
cuesj-1234	52	60	and	and	CCONJ
cuesj-1234	52	61	a	a	DET
cuesj-1234	52	62	carrier	carrier	NOUN
cuesj-1234	52	63	are	be	AUX
cuesj-1234	52	64	dissolved	dissolve	VERB
cuesj-1234	52	65	in	in	ADP
cuesj-1234	52	66	a	a	DET
cuesj-1234	52	67	volatile	volatile	ADJ
cuesj-1234	52	68	solvent	solvent	NOUN
cuesj-1234	52	69	to	to	PART
cuesj-1234	52	70	achieve	achieve	VERB
cuesj-1234	52	71	a	a	DET
cuesj-1234	52	72	homogeneous	homogeneous	ADJ
cuesj-1234	52	73	mixture	mixture	NOUN
cuesj-1234	52	74	.	.	PUNCT
cuesj-1234	53	1	the	the	DET
cuesj-1234	53	2	solid	solid	ADJ
cuesj-1234	53	3	dispersion	dispersion	NOUN
cuesj-1234	53	4	is	be	AUX
cuesj-1234	53	5	fully	fully	ADV
cuesj-1234	53	6	formed	form	VERB
cuesj-1234	53	7	after	after	ADP
cuesj-1234	53	8	the	the	DET
cuesj-1234	53	9	evaporation	evaporation	NOUN
cuesj-1234	53	10	of	of	ADP
cuesj-1234	53	11	the	the	DET
cuesj-1234	53	12	solvent.[27	solvent.[27	NOUN
cuesj-1234	53	13	]	]	X
cuesj-1234	53	14	it	it	PRON
cuesj-1234	53	15	was	be	AUX
cuesj-1234	53	16	used	use	VERB
cuesj-1234	53	17	in	in	ADP
cuesj-1234	53	18	this	this	DET
cuesj-1234	53	19	experiment	experiment	NOUN
cuesj-1234	53	20	for	for	ADP
cuesj-1234	53	21	its	its	PRON
cuesj-1234	53	22	relative	relative	ADJ
cuesj-1234	53	23	ease	ease	NOUN
cuesj-1234	53	24	and	and	CCONJ
cuesj-1234	53	25	simplicity	simplicity	NOUN
cuesj-1234	53	26	.	.	PUNCT
cuesj-1234	54	1	the	the	DET
cuesj-1234	54	2	disadvantages	disadvantage	NOUN
cuesj-1234	54	3	of	of	ADP
cuesj-1234	54	4	solvent	solvent	ADJ
cuesj-1234	54	5	evaporation	evaporation	NOUN
cuesj-1234	54	6	include	include	VERB
cuesj-1234	54	7	difficulty	difficulty	NOUN
cuesj-1234	54	8	in	in	ADP
cuesj-1234	54	9	fully	fully	ADV
cuesj-1234	54	10	removing	remove	VERB
cuesj-1234	54	11	the	the	DET
cuesj-1234	54	12	solvent	solvent	NOUN
cuesj-1234	54	13	and	and	CCONJ
cuesj-1234	54	14	choosing	choose	VERB
cuesj-1234	54	15	a	a	DET
cuesj-1234	54	16	common	common	ADJ
cuesj-1234	54	17	solvent	solvent	NOUN
cuesj-1234	54	18	for	for	ADP
cuesj-1234	54	19	the	the	DET
cuesj-1234	54	20	solutes.[30	solutes.[30	PROPN
cuesj-1234	54	21	]	]	PUNCT
cuesj-1234	54	22	simple	simple	ADJ
cuesj-1234	54	23	ethanol	ethanol	NOUN
cuesj-1234	54	24	was	be	AUX
cuesj-1234	54	25	satisfactory	satisfactory	ADJ
cuesj-1234	54	26	,	,	PUNCT
cuesj-1234	54	27	however	however	ADV
cuesj-1234	54	28	,	,	PUNCT
cuesj-1234	54	29	in	in	ADP
cuesj-1234	54	30	dissolving	dissolve	VERB
cuesj-1234	54	31	simvastatin	simvastatin	NOUN
cuesj-1234	54	32	and	and	CCONJ
cuesj-1234	54	33	its	its	PRON
cuesj-1234	54	34	excipients	excipient	NOUN
cuesj-1234	54	35	.	.	PUNCT
cuesj-1234	55	1	many	many	ADJ
cuesj-1234	55	2	attempts	attempt	NOUN
cuesj-1234	55	3	at	at	ADP
cuesj-1234	55	4	improving	improve	VERB
cuesj-1234	55	5	the	the	DET
cuesj-1234	55	6	solubility	solubility	NOUN
cuesj-1234	55	7	of	of	ADP
cuesj-1234	55	8	simvastatin	simvastatin	NOUN
cuesj-1234	55	9	have	have	AUX
cuesj-1234	55	10	been	be	AUX
cuesj-1234	55	11	made	make	VERB
cuesj-1234	55	12	,	,	PUNCT
cuesj-1234	55	13	using	use	VERB
cuesj-1234	55	14	various	various	ADJ
cuesj-1234	55	15	methods	method	NOUN
cuesj-1234	55	16	,	,	PUNCT
cuesj-1234	55	17	most	most	ADV
cuesj-1234	55	18	commonly	commonly	ADV
cuesj-1234	55	19	with	with	ADP
cuesj-1234	55	20	solid	solid	ADJ
cuesj-1234	55	21	dispersions	dispersion	NOUN
cuesj-1234	55	22	.	.	PUNCT
cuesj-1234	56	1	in	in	ADP
cuesj-1234	56	2	one	one	NUM
cuesj-1234	56	3	such	such	ADJ
cuesj-1234	56	4	attempt	attempt	NOUN
cuesj-1234	56	5	,	,	PUNCT
cuesj-1234	56	6	arginine	arginine	NOUN
cuesj-1234	56	7	was	be	AUX
cuesj-1234	56	8	used	use	VERB
cuesj-1234	56	9	as	as	ADP
cuesj-1234	56	10	a	a	DET
cuesj-1234	56	11	cosolvent	cosolvent	NOUN
cuesj-1234	56	12	with	with	ADP
cuesj-1234	56	13	simvastatin	simvastatin	NOUN
cuesj-1234	56	14	in	in	ADP
cuesj-1234	56	15	different	different	ADJ
cuesj-1234	56	16	molar	molar	ADJ
cuesj-1234	56	17	concentrations	concentration	NOUN
cuesj-1234	56	18	,	,	PUNCT
cuesj-1234	56	19	and	and	CCONJ
cuesj-1234	56	20	the	the	DET
cuesj-1234	56	21	results	result	NOUN
cuesj-1234	56	22	showed	show	VERB
cuesj-1234	56	23	a	a	DET
cuesj-1234	56	24	massive	massive	ADJ
cuesj-1234	56	25	improvement	improvement	NOUN
cuesj-1234	56	26	in	in	ADP
cuesj-1234	56	27	the	the	DET
cuesj-1234	56	28	aqueous	aqueous	ADJ
cuesj-1234	56	29	solubility	solubility	NOUN
cuesj-1234	56	30	of	of	ADP
cuesj-1234	56	31	the	the	DET
cuesj-1234	56	32	drug	drug	NOUN
cuesj-1234	56	33	.	.	PUNCT
cuesj-1234	57	1	the	the	DET
cuesj-1234	57	2	final	final	ADJ
cuesj-1234	57	3	maximum	maximum	NOUN
cuesj-1234	57	4	solubility	solubility	NOUN
cuesj-1234	57	5	showed	show	VERB
cuesj-1234	57	6	an	an	DET
cuesj-1234	57	7	incredible	incredible	ADJ
cuesj-1234	57	8	almost	almost	ADV
cuesj-1234	57	9	13,000	13,000	NUM
cuesj-1234	57	10	-	-	PUNCT
cuesj-1234	57	11	fold	fold	ADJ
cuesj-1234	57	12	improvement	improvement	NOUN
cuesj-1234	57	13	,	,	PUNCT
cuesj-1234	57	14	in	in	ADP
cuesj-1234	57	15	which	which	PRON
cuesj-1234	57	16	the	the	DET
cuesj-1234	57	17	intrinsic	intrinsic	ADJ
cuesj-1234	57	18	solubility	solubility	NOUN
cuesj-1234	57	19	jumped	jump	VERB
cuesj-1234	57	20	from	from	ADP
cuesj-1234	57	21	0.003164	0.003164	NUM
cuesj-1234	57	22	mmol	mmol	NOUN
cuesj-1234	57	23	/	/	SYM
cuesj-1234	57	24	ml	ml	NOUN
cuesj-1234	57	25	to	to	ADP
cuesj-1234	57	26	70.4	70.4	NUM
cuesj-1234	57	27	mmol	mmol	NOUN
cuesj-1234	57	28	/	/	SYM
cuesj-1234	57	29	ml.[24	ml.[24	NOUN
cuesj-1234	57	30	]	]	PUNCT
cuesj-1234	57	31	the	the	DET
cuesj-1234	57	32	authors	author	NOUN
cuesj-1234	57	33	’	'	PUNCT
cuesj-1234	57	34	proposed	propose	VERB
cuesj-1234	57	35	explanation	explanation	NOUN
cuesj-1234	57	36	for	for	ADP
cuesj-1234	57	37	this	this	DET
cuesj-1234	57	38	increase	increase	NOUN
cuesj-1234	57	39	is	be	AUX
cuesj-1234	57	40	the	the	DET
cuesj-1234	57	41	formation	formation	NOUN
cuesj-1234	57	42	of	of	ADP
cuesj-1234	57	43	a	a	DET
cuesj-1234	57	44	more	more	ADV
cuesj-1234	57	45	favorable	favorable	ADJ
cuesj-1234	57	46	environment	environment	NOUN
cuesj-1234	57	47	for	for	ADP
cuesj-1234	57	48	the	the	DET
cuesj-1234	57	49	solubility	solubility	NOUN
cuesj-1234	57	50	of	of	ADP
cuesj-1234	57	51	simvastatin	simvastatin	NOUN
cuesj-1234	57	52	.	.	PUNCT
cuesj-1234	58	1	this	this	PRON
cuesj-1234	58	2	is	be	AUX
cuesj-1234	58	3	achieved	achieve	VERB
cuesj-1234	58	4	through	through	ADP
cuesj-1234	58	5	both	both	CCONJ
cuesj-1234	58	6	solute	solute	NOUN
cuesj-1234	58	7	-	-	PUNCT
cuesj-1234	58	8	solvent	solvent	ADJ
cuesj-1234	58	9	and	and	CCONJ
cuesj-1234	58	10	solute	solute	NOUN
cuesj-1234	58	11	-	-	PUNCT
cuesj-1234	58	12	cosolute	cosolute	NOUN
cuesj-1234	58	13	interaction	interaction	NOUN
cuesj-1234	58	14	in	in	ADP
cuesj-1234	58	15	which	which	PRON
cuesj-1234	58	16	the	the	DET
cuesj-1234	58	17	arginine	arginine	NOUN
cuesj-1234	58	18	forms	form	VERB
cuesj-1234	58	19	a	a	DET
cuesj-1234	58	20	complex	complex	NOUN
cuesj-1234	58	21	with	with	ADP
cuesj-1234	58	22	the	the	DET
cuesj-1234	58	23	simvastatin	simvastatin	NOUN
cuesj-1234	58	24	,	,	PUNCT
cuesj-1234	58	25	making	make	VERB
cuesj-1234	58	26	it	it	PRON
cuesj-1234	58	27	more	more	ADV
cuesj-1234	58	28	polar	polar	ADJ
cuesj-1234	58	29	and	and	CCONJ
cuesj-1234	58	30	readily	readily	ADV
cuesj-1234	58	31	soluble	soluble	ADJ
cuesj-1234	58	32	.	.	PUNCT
cuesj-1234	59	1	another	another	DET
cuesj-1234	59	2	experiment	experiment	NOUN
cuesj-1234	59	3	improved	improve	VERB
cuesj-1234	59	4	simvastatin	simvastatin	PROPN
cuesj-1234	59	5	’s	’s	PART
cuesj-1234	59	6	solubility	solubility	NOUN
cuesj-1234	59	7	more	more	ADJ
cuesj-1234	59	8	than	than	ADP
cuesj-1234	59	9	5	5	NUM
cuesj-1234	59	10	-	-	ADJ
cuesj-1234	59	11	fold	fold	ADJ
cuesj-1234	59	12	using	use	VERB
cuesj-1234	59	13	polymeric	polymeric	ADJ
cuesj-1234	59	14	blends	blend	NOUN
cuesj-1234	59	15	of	of	ADP
cuesj-1234	59	16	polyvinylpyrrolidone	polyvinylpyrrolidone	NOUN
cuesj-1234	59	17	and	and	CCONJ
cuesj-1234	59	18	similar	similar	ADJ
cuesj-1234	59	19	substances	substance	NOUN
cuesj-1234	59	20	,	,	PUNCT
cuesj-1234	59	21	with	with	ADP
cuesj-1234	59	22	solid	solid	ADJ
cuesj-1234	59	23	dispersion	dispersion	NOUN
cuesj-1234	59	24	.	.	PUNCT
cuesj-1234	60	1	this	this	DET
cuesj-1234	60	2	time	time	NOUN
cuesj-1234	60	3	,	,	PUNCT
cuesj-1234	60	4	however	however	ADV
cuesj-1234	60	5	,	,	PUNCT
cuesj-1234	60	6	no	no	DET
cuesj-1234	60	7	solvent	solvent	NOUN
cuesj-1234	60	8	was	be	AUX
cuesj-1234	60	9	used	use	VERB
cuesj-1234	60	10	.	.	PUNCT
cuesj-1234	61	1	instead	instead	ADV
cuesj-1234	61	2	,	,	PUNCT
cuesj-1234	61	3	the	the	DET
cuesj-1234	61	4	hot	hot	ADJ
cuesj-1234	61	5	melt	melt	NOUN
cuesj-1234	61	6	and	and	CCONJ
cuesj-1234	61	7	twinscrew	twinscrew	ADJ
cuesj-1234	61	8	melt	melt	VERB
cuesj-1234	61	9	granulation	granulation	NOUN
cuesj-1234	61	10	methods	method	NOUN
cuesj-1234	61	11	were	be	AUX
cuesj-1234	61	12	used	use	VERB
cuesj-1234	61	13	.	.	PUNCT
cuesj-1234	62	1	the	the	DET
cuesj-1234	62	2	release	release	NOUN
cuesj-1234	62	3	profile	profile	NOUN
cuesj-1234	62	4	of	of	ADP
cuesj-1234	62	5	these	these	DET
cuesj-1234	62	6	mixtures	mixture	NOUN
cuesj-1234	62	7	was	be	AUX
cuesj-1234	62	8	the	the	DET
cuesj-1234	62	9	same	same	ADJ
cuesj-1234	62	10	as	as	ADP
cuesj-1234	62	11	that	that	PRON
cuesj-1234	62	12	of	of	ADP
cuesj-1234	62	13	normally	normally	ADV
cuesj-1234	62	14	formulated	formulate	VERB
cuesj-1234	62	15	simvastatin	simvastatin	NOUN
cuesj-1234	62	16	.	.	PUNCT
cuesj-1234	63	1	in	in	ADP
cuesj-1234	63	2	one	one	NUM
cuesj-1234	63	3	of	of	ADP
cuesj-1234	63	4	their	their	PRON
cuesj-1234	63	5	product	product	NOUN
cuesj-1234	63	6	results	result	NOUN
cuesj-1234	63	7	,	,	PUNCT
cuesj-1234	63	8	the	the	DET
cuesj-1234	63	9	values	value	NOUN
cuesj-1234	63	10	showed	show	VERB
cuesj-1234	63	11	a	a	DET
cuesj-1234	63	12	large	large	ADJ
cuesj-1234	63	13	increase	increase	NOUN
cuesj-1234	63	14	in	in	ADP
cuesj-1234	63	15	miscibility	miscibility	NOUN
cuesj-1234	63	16	,	,	PUNCT
cuesj-1234	63	17	but	but	CCONJ
cuesj-1234	63	18	not	not	PART
cuesj-1234	63	19	a	a	DET
cuesj-1234	63	20	proportional	proportional	ADJ
cuesj-1234	63	21	increase	increase	NOUN
cuesj-1234	63	22	in	in	ADP
cuesj-1234	63	23	solubility	solubility	NOUN
cuesj-1234	63	24	,	,	PUNCT
cuesj-1234	63	25	which	which	PRON
cuesj-1234	63	26	shows	show	VERB
cuesj-1234	63	27	they	they	PRON
cuesj-1234	63	28	are	be	AUX
cuesj-1234	63	29	not	not	PART
cuesj-1234	63	30	always	always	ADV
cuesj-1234	63	31	directly	directly	ADV
cuesj-1234	63	32	correlated.[31	correlated.[31	VERB
cuesj-1234	63	33	]	]	X
cuesj-1234	63	34	yet	yet	CCONJ
cuesj-1234	64	1	another	another	DET
cuesj-1234	64	2	experiment	experiment	NOUN
cuesj-1234	64	3	utilized	utilize	VERB
cuesj-1234	64	4	citric	citric	ADJ
cuesj-1234	64	5	acid	acid	NOUN
cuesj-1234	64	6	and	and	CCONJ
cuesj-1234	64	7	co	co	NOUN
cuesj-1234	64	8	-	-	NOUN
cuesj-1234	64	9	crystallization	crystallization	NOUN
cuesj-1234	64	10	as	as	ADP
cuesj-1234	64	11	a	a	DET
cuesj-1234	64	12	method	method	NOUN
cuesj-1234	64	13	in	in	ADP
cuesj-1234	64	14	the	the	DET
cuesj-1234	64	15	improvement	improvement	NOUN
cuesj-1234	64	16	of	of	ADP
cuesj-1234	64	17	simvastatin	simvastatin	PROPN
cuesj-1234	64	18	’s	’s	PART
cuesj-1234	64	19	solubility.[32	solubility.[32	PROPN
cuesj-1234	64	20	]	]	PUNCT
cuesj-1234	64	21	this	this	PRON
cuesj-1234	64	22	showed	show	VERB
cuesj-1234	64	23	an	an	DET
cuesj-1234	64	24	increase	increase	NOUN
cuesj-1234	64	25	in	in	ADP
cuesj-1234	64	26	solubility	solubility	NOUN
cuesj-1234	64	27	,	,	PUNCT
cuesj-1234	64	28	and	and	CCONJ
cuesj-1234	64	29	also	also	ADV
cuesj-1234	64	30	in	in	ADP
cuesj-1234	64	31	the	the	DET
cuesj-1234	64	32	release	release	NOUN
cuesj-1234	64	33	profile	profile	NOUN
cuesj-1234	64	34	and	and	CCONJ
cuesj-1234	64	35	stability	stability	NOUN
cuesj-1234	64	36	of	of	ADP
cuesj-1234	64	37	the	the	DET
cuesj-1234	64	38	drug	drug	NOUN
cuesj-1234	64	39	.	.	PUNCT
cuesj-1234	65	1	simvastatin	simvastatin	PROPN
cuesj-1234	65	2	has	have	AUX
cuesj-1234	65	3	even	even	ADV
cuesj-1234	65	4	been	be	AUX
cuesj-1234	65	5	used	use	VERB
cuesj-1234	65	6	topically	topically	ADV
cuesj-1234	65	7	to	to	PART
cuesj-1234	65	8	improve	improve	VERB
cuesj-1234	65	9	wound	wound	ADJ
cuesj-1234	65	10	healing	healing	NOUN
cuesj-1234	65	11	,	,	PUNCT
cuesj-1234	65	12	and	and	CCONJ
cuesj-1234	65	13	an	an	DET
cuesj-1234	65	14	experiment	experiment	NOUN
cuesj-1234	65	15	was	be	AUX
cuesj-1234	65	16	done	do	VERB
cuesj-1234	65	17	to	to	PART
cuesj-1234	65	18	enhance	enhance	VERB
cuesj-1234	65	19	topical	topical	ADJ
cuesj-1234	65	20	simvastatin	simvastatin	NOUN
cuesj-1234	65	21	’s	’s	PART
cuesj-1234	65	22	solubility	solubility	NOUN
cuesj-1234	65	23	to	to	PART
cuesj-1234	65	24	make	make	VERB
cuesj-1234	65	25	it	it	PRON
cuesj-1234	65	26	more	more	ADV
cuesj-1234	65	27	practical	practical	ADJ
cuesj-1234	65	28	to	to	PART
cuesj-1234	65	29	use	use	VERB
cuesj-1234	65	30	externally.[33	externally.[33	NOUN
cuesj-1234	65	31	]	]	PUNCT
cuesj-1234	65	32	the	the	DET
cuesj-1234	65	33	experiment	experiment	NOUN
cuesj-1234	65	34	used	use	VERB
cuesj-1234	65	35	various	various	ADJ
cuesj-1234	65	36	solvents	solvent	NOUN
cuesj-1234	65	37	such	such	ADJ
cuesj-1234	65	38	as	as	ADP
cuesj-1234	65	39	buffered	buffer	VERB
cuesj-1234	65	40	ethanol	ethanol	NOUN
cuesj-1234	65	41	,	,	PUNCT
cuesj-1234	65	42	methanol	methanol	NOUN
cuesj-1234	65	43	,	,	PUNCT
cuesj-1234	65	44	and	and	CCONJ
cuesj-1234	65	45	dimethyl	dimethyl	NOUN
cuesj-1234	65	46	sulfoxide	sulfoxide	NOUN
cuesj-1234	65	47	,	,	PUNCT
cuesj-1234	65	48	along	along	ADP
cuesj-1234	65	49	with	with	ADP
cuesj-1234	65	50	polymers	polymer	NOUN
cuesj-1234	65	51	such	such	ADJ
cuesj-1234	65	52	as	as	ADP
cuesj-1234	65	53	chitosan	chitosan	NOUN
cuesj-1234	65	54	,	,	PUNCT
cuesj-1234	65	55	and	and	CCONJ
cuesj-1234	65	56	cellulose	cellulose	NOUN
cuesj-1234	65	57	derivatives	derivative	NOUN
cuesj-1234	65	58	such	such	ADJ
cuesj-1234	65	59	as	as	ADP
cuesj-1234	65	60	carboxymethyl	carboxymethyl	NOUN
cuesj-1234	65	61	cellulose	cellulose	NOUN
cuesj-1234	65	62	and	and	CCONJ
cuesj-1234	65	63	hydroxypropyl	hydroxypropyl	VERB
cuesj-1234	65	64	methyl	methyl	NOUN
cuesj-1234	65	65	cellulose	cellulose	NOUN
cuesj-1234	65	66	.	.	PUNCT
cuesj-1234	66	1	the	the	DET
cuesj-1234	66	2	findings	finding	NOUN
cuesj-1234	66	3	showed	show	VERB
cuesj-1234	66	4	a	a	DET
cuesj-1234	66	5	remarkable	remarkable	ADJ
cuesj-1234	66	6	50	50	NUM
cuesj-1234	66	7	-	-	ADJ
cuesj-1234	66	8	fold	fold	ADJ
cuesj-1234	66	9	increase	increase	NOUN
cuesj-1234	66	10	in	in	ADP
cuesj-1234	66	11	simvastatin	simvastatin	PROPN
cuesj-1234	66	12	’s	’s	PART
cuesj-1234	66	13	solubility	solubility	NOUN
cuesj-1234	66	14	with	with	ADP
cuesj-1234	66	15	ethanol	ethanol	NOUN
cuesj-1234	66	16	and	and	CCONJ
cuesj-1234	66	17	chitosan	chitosan	NOUN
cuesj-1234	66	18	.	.	PUNCT
cuesj-1234	67	1	the	the	DET
cuesj-1234	67	2	objective	objective	NOUN
cuesj-1234	67	3	of	of	ADP
cuesj-1234	67	4	this	this	DET
cuesj-1234	67	5	experiment	experiment	NOUN
cuesj-1234	67	6	is	be	AUX
cuesj-1234	67	7	to	to	PART
cuesj-1234	67	8	improve	improve	VERB
cuesj-1234	67	9	the	the	DET
cuesj-1234	67	10	solubility	solubility	NOUN
cuesj-1234	67	11	of	of	ADP
cuesj-1234	67	12	simvastatin	simvastatin	NOUN
cuesj-1234	67	13	by	by	ADP
cuesj-1234	67	14	forming	form	VERB
cuesj-1234	67	15	a	a	DET
cuesj-1234	67	16	solid	solid	ADJ
cuesj-1234	67	17	dispersion	dispersion	NOUN
cuesj-1234	67	18	,	,	PUNCT
cuesj-1234	67	19	using	use	VERB
cuesj-1234	67	20	the	the	DET
cuesj-1234	67	21	solvent	solvent	ADJ
cuesj-1234	67	22	evaporation	evaporation	NOUN
cuesj-1234	67	23	method	method	NOUN
cuesj-1234	67	24	with	with	ADP
cuesj-1234	67	25	ethanol	ethanol	NOUN
cuesj-1234	67	26	as	as	ADP
cuesj-1234	67	27	in	in	ADP
cuesj-1234	67	28	previous	previous	ADJ
cuesj-1234	67	29	experiments	experiment	NOUN
cuesj-1234	67	30	,	,	PUNCT
cuesj-1234	67	31	with	with	ADP
cuesj-1234	67	32	sodium	sodium	NOUN
cuesj-1234	67	33	docusate	docusate	NOUN
cuesj-1234	67	34	and	and	CCONJ
cuesj-1234	67	35	l	l	NOUN
cuesj-1234	67	36	-	-	NOUN
cuesj-1234	67	37	isoleucine	isoleucine	NOUN
cuesj-1234	67	38	combined	combine	VERB
cuesj-1234	67	39	in	in	ADP
cuesj-1234	67	40	various	various	ADJ
cuesj-1234	67	41	ratios	ratio	NOUN
cuesj-1234	67	42	in	in	ADP
cuesj-1234	67	43	order	order	NOUN
cuesj-1234	67	44	to	to	PART
cuesj-1234	67	45	ascertain	ascertain	VERB
cuesj-1234	67	46	which	which	DET
cuesj-1234	67	47	combination	combination	NOUN
cuesj-1234	67	48	has	have	VERB
cuesj-1234	67	49	the	the	DET
cuesj-1234	67	50	greatest	great	ADJ
cuesj-1234	67	51	improvement	improvement	NOUN
cuesj-1234	67	52	.	.	PUNCT
cuesj-1234	68	1	all	all	DET
cuesj-1234	68	2	the	the	DET
cuesj-1234	68	3	ingredients	ingredient	NOUN
cuesj-1234	68	4	are	be	AUX
cuesj-1234	68	5	easily	easily	ADV
cuesj-1234	68	6	available	available	ADJ
cuesj-1234	68	7	,	,	PUNCT
cuesj-1234	68	8	making	make	VERB
cuesj-1234	68	9	it	it	PRON
cuesj-1234	68	10	easy	easy	ADJ
cuesj-1234	68	11	to	to	ADP
cuesj-1234	68	12	fine	fine	ADJ
cuesj-1234	68	13	-	-	PUNCT
cuesj-1234	68	14	tune	tune	NOUN
cuesj-1234	68	15	all	all	DET
cuesj-1234	68	16	the	the	DET
cuesj-1234	68	17	measurements	measurement	NOUN
cuesj-1234	68	18	in	in	ADP
cuesj-1234	68	19	repeated	repeat	VERB
cuesj-1234	68	20	experiments	experiment	NOUN
cuesj-1234	68	21	.	.	PUNCT
cuesj-1234	69	1	instruments	instrument	NOUN
cuesj-1234	69	2	and	and	CCONJ
cuesj-1234	69	3	methodology	methodology	NOUN
cuesj-1234	69	4	materials	material	NOUN
cuesj-1234	69	5	and	and	CCONJ
cuesj-1234	69	6	instruments	instrument	NOUN
cuesj-1234	69	7	•	•	NOUN
cuesj-1234	69	8	simvastatin	simvastatin	NOUN
cuesj-1234	69	9	100	100	NUM
cuesj-1234	69	10	g	g	NOUN
cuesj-1234	69	11	(	(	PUNCT
cuesj-1234	69	12	powder	powder	NOUN
cuesj-1234	69	13	form	form	NOUN
cuesj-1234	69	14	)	)	PUNCT
cuesj-1234	69	15	as	as	SCONJ
cuesj-1234	69	16	shown	show	VERB
cuesj-1234	69	17	in	in	ADP
cuesj-1234	69	18	figure	figure	NOUN
cuesj-1234	69	19	6	6	NUM
cuesj-1234	69	20	•	•	NUM
cuesj-1234	69	21	l	l	NOUN
cuesj-1234	69	22	-	-	NOUN
cuesj-1234	69	23	isoleucine	isoleucine	ADJ
cuesj-1234	69	24	100	100	NUM
cuesj-1234	69	25	g	g	PROPN
cuesj-1234	69	26	simson	simson	PROPN
cuesj-1234	69	27	brand	brand	PROPN
cuesj-1234	69	28	(	(	PUNCT
cuesj-1234	69	29	powder	powder	NOUN
cuesj-1234	69	30	form	form	NOUN
cuesj-1234	69	31	)	)	PUNCT
cuesj-1234	69	32	•	•	NUM
cuesj-1234	69	33	sodium	sodium	NOUN
cuesj-1234	69	34	docusate	docusate	VERB
cuesj-1234	69	35	50	50	NUM
cuesj-1234	69	36	g	g	NOUN
cuesj-1234	69	37	(	(	PUNCT
cuesj-1234	69	38	semisolid	semisolid	NOUN
cuesj-1234	69	39	form	form	NOUN
cuesj-1234	69	40	)	)	PUNCT
cuesj-1234	69	41	•	•	NUM
cuesj-1234	69	42	ethanol	ethanol	NOUN
cuesj-1234	69	43	100	100	NUM
cuesj-1234	69	44	%	%	NOUN
cuesj-1234	69	45	•	•	ADP
cuesj-1234	69	46	distilled	distil	VERB
cuesj-1234	69	47	water	water	NOUN
cuesj-1234	69	48	•	•	NOUN
cuesj-1234	69	49	volumetric	volumetric	NOUN
cuesj-1234	69	50	flasks	flask	NOUN
cuesj-1234	69	51	(	(	PUNCT
cuesj-1234	69	52	10	10	NUM
cuesj-1234	69	53	ml	ml	NOUN
cuesj-1234	69	54	)	)	PUNCT
cuesj-1234	69	55	•	•	NOUN
cuesj-1234	69	56	pipette	pipette	NOUN
cuesj-1234	69	57	•	•	NOUN
cuesj-1234	69	58	graduated	graduate	VERB
cuesj-1234	69	59	cylinder	cylinder	NOUN
cuesj-1234	69	60	(	(	PUNCT
cuesj-1234	69	61	25	25	NUM
cuesj-1234	69	62	ml	ml	NOUN
cuesj-1234	69	63	)	)	PUNCT
cuesj-1234	69	64	•	•	NOUN
cuesj-1234	69	65	mortars	mortar	NOUN
cuesj-1234	69	66	and	and	CCONJ
cuesj-1234	69	67	pestles	pestle	NOUN
cuesj-1234	69	68	(	(	PUNCT
cuesj-1234	69	69	ceramic	ceramic	NOUN
cuesj-1234	69	70	and	and	CCONJ
cuesj-1234	69	71	glass	glass	NOUN
cuesj-1234	69	72	)	)	PUNCT
cuesj-1234	69	73	•	•	NUM
cuesj-1234	69	74	filter	filter	NOUN
cuesj-1234	69	75	paper	paper	NOUN
cuesj-1234	69	76	,	,	PUNCT
cuesj-1234	69	77	whitman	whitman	PROPN
cuesj-1234	69	78	brand	brand	PROPN
cuesj-1234	69	79	(	(	PUNCT
cuesj-1234	69	80	42	42	NUM
cuesj-1234	69	81	ashless	ashless	NOUN
cuesj-1234	69	82	)	)	PUNCT
cuesj-1234	69	83	•	•	ADP
cuesj-1234	69	84	various	various	ADJ
cuesj-1234	69	85	beakers	beaker	NOUN
cuesj-1234	69	86	(	(	PUNCT
cuesj-1234	69	87	10	10	NUM
cuesj-1234	69	88	,	,	PUNCT
cuesj-1234	69	89	20	20	NUM
cuesj-1234	69	90	,	,	PUNCT
cuesj-1234	69	91	and	and	CCONJ
cuesj-1234	69	92	50	50	NUM
cuesj-1234	69	93	ml	ml	NOUN
cuesj-1234	69	94	)	)	PUNCT
cuesj-1234	69	95	figure	figure	NOUN
cuesj-1234	69	96	4	4	NUM
cuesj-1234	69	97	:	:	PUNCT
cuesj-1234	69	98	sodium	sodium	NOUN
cuesj-1234	69	99	docusate	docusate	NOUN
cuesj-1234	69	100	structure[20	structure[20	NOUN
cuesj-1234	69	101	]	]	PUNCT
cuesj-1234	69	102	figure	figure	NOUN
cuesj-1234	69	103	5	5	NUM
cuesj-1234	69	104	:	:	PUNCT
cuesj-1234	69	105	l	l	ADJ
cuesj-1234	69	106	-	-	ADJ
cuesj-1234	69	107	isoleucine	isoleucine	ADJ
cuesj-1234	69	108	structure[26	structure[26	PROPN
cuesj-1234	69	109	]	]	X
cuesj-1234	69	110	al	al	PROPN
cuesj-1234	69	111	-	-	PUNCT
cuesj-1234	69	112	jumaili	jumaili	PROPN
cuesj-1234	69	113	,	,	PUNCT
cuesj-1234	69	114	et	et	PROPN
cuesj-1234	69	115	al	al	PROPN
cuesj-1234	69	116	.	.	PROPN
cuesj-1234	69	117	:	:	PUNCT
cuesj-1234	70	1	enhancing	enhance	VERB
cuesj-1234	70	2	solubility	solubility	NOUN
cuesj-1234	70	3	of	of	ADP
cuesj-1234	70	4	simvastatin	simvastatin	NOUN
cuesj-1234	70	5	with	with	ADP
cuesj-1234	70	6	l	l	NOUN
cuesj-1234	70	7	-	-	NOUN
cuesj-1234	70	8	isoleucine	isoleucine	ADJ
cuesj-1234	70	9	and	and	CCONJ
cuesj-1234	70	10	sodium	sodium	NOUN
cuesj-1234	70	11	docusate	docusate	NOUN
cuesj-1234	70	12	29	29	NUM
cuesj-1234	70	13	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	70	14	cuesj	cuesj	NOUN
cuesj-1234	70	15	2025	2025	NUM
cuesj-1234	70	16	,	,	PUNCT
cuesj-1234	70	17	9	9	NUM
cuesj-1234	70	18	(	(	PUNCT
cuesj-1234	70	19	2	2	NUM
cuesj-1234	70	20	):	):	PUNCT
cuesj-1234	70	21	26	26	NUM
cuesj-1234	70	22	-	-	SYM
cuesj-1234	70	23	32	32	NUM
cuesj-1234	70	24	•	•	NUM
cuesj-1234	70	25	highly	highly	ADV
cuesj-1234	70	26	accurate	accurate	ADJ
cuesj-1234	70	27	balance	balance	NOUN
cuesj-1234	70	28	•	•	NOUN
cuesj-1234	70	29	spectrophotometer	spectrophotometer	NOUN
cuesj-1234	70	30	•	•	NOUN
cuesj-1234	70	31	magnetic	magnetic	ADJ
cuesj-1234	70	32	stirrer	stirrer	NOUN
cuesj-1234	70	33	and	and	CCONJ
cuesj-1234	70	34	heater	heater	NOUN
cuesj-1234	70	35	•	•	NOUN
cuesj-1234	70	36	oven	oven	PROPN
cuesj-1234	70	37	(	(	PUNCT
cuesj-1234	70	38	set	set	VERB
cuesj-1234	70	39	at	at	ADP
cuesj-1234	70	40	32	32	NUM
cuesj-1234	70	41	°	°	NOUN
cuesj-1234	70	42	c	c	NOUN
cuesj-1234	70	43	)	)	PUNCT
cuesj-1234	70	44	.	.	PUNCT
cuesj-1234	71	1	methodology	methodology	NOUN
cuesj-1234	71	2	two	two	NUM
cuesj-1234	71	3	solvents	solvent	NOUN
cuesj-1234	71	4	were	be	AUX
cuesj-1234	71	5	prepared	prepare	VERB
cuesj-1234	71	6	in	in	ADP
cuesj-1234	71	7	separate	separate	ADJ
cuesj-1234	71	8	beakers	beaker	NOUN
cuesj-1234	71	9	,	,	PUNCT
cuesj-1234	71	10	both	both	PRON
cuesj-1234	71	11	consisting	consist	VERB
cuesj-1234	71	12	of	of	ADP
cuesj-1234	71	13	80	80	NUM
cuesj-1234	71	14	ml	ml	NOUN
cuesj-1234	71	15	of	of	ADP
cuesj-1234	71	16	pure	pure	ADJ
cuesj-1234	71	17	ethanol	ethanol	NOUN
cuesj-1234	71	18	and	and	CCONJ
cuesj-1234	71	19	20	20	NUM
cuesj-1234	71	20	ml	ml	NOUN
cuesj-1234	71	21	of	of	ADP
cuesj-1234	71	22	distilled	distil	VERB
cuesj-1234	71	23	water	water	NOUN
cuesj-1234	71	24	.	.	PUNCT
cuesj-1234	72	1	ten	ten	NUM
cuesj-1234	72	2	milligrams	milligram	NOUN
cuesj-1234	72	3	(	(	PUNCT
cuesj-1234	72	4	mg	mg	NOUN
cuesj-1234	72	5	)	)	PUNCT
cuesj-1234	72	6	of	of	ADP
cuesj-1234	72	7	simvastatin	simvastatin	NOUN
cuesj-1234	72	8	were	be	AUX
cuesj-1234	72	9	added	add	VERB
cuesj-1234	72	10	to	to	ADP
cuesj-1234	72	11	one	one	NUM
cuesj-1234	72	12	beaker	beaker	NOUN
cuesj-1234	72	13	,	,	PUNCT
cuesj-1234	72	14	which	which	PRON
cuesj-1234	72	15	resulted	result	VERB
cuesj-1234	72	16	in	in	ADP
cuesj-1234	72	17	a	a	DET
cuesj-1234	72	18	concentration	concentration	NOUN
cuesj-1234	72	19	of	of	ADP
cuesj-1234	72	20	10	10	NUM
cuesj-1234	72	21	mg/100	mg/100	NOUN
cuesj-1234	72	22	ml	ml	NOUN
cuesj-1234	72	23	(	(	PUNCT
cuesj-1234	72	24	100	100	NUM
cuesj-1234	72	25	µg	µg	NOUN
cuesj-1234	72	26	/	/	SYM
cuesj-1234	72	27	ml	ml	NOUN
cuesj-1234	72	28	)	)	PUNCT
cuesj-1234	72	29	and	and	CCONJ
cuesj-1234	72	30	was	be	AUX
cuesj-1234	72	31	used	use	VERB
cuesj-1234	72	32	as	as	ADP
cuesj-1234	72	33	the	the	DET
cuesj-1234	72	34	stock	stock	NOUN
cuesj-1234	72	35	solution	solution	NOUN
cuesj-1234	72	36	.	.	PUNCT
cuesj-1234	73	1	the	the	DET
cuesj-1234	73	2	solvent	solvent	NOUN
cuesj-1234	73	3	without	without	ADP
cuesj-1234	73	4	simvastatin	simvastatin	NOUN
cuesj-1234	73	5	was	be	AUX
cuesj-1234	73	6	used	use	VERB
cuesj-1234	73	7	as	as	ADP
cuesj-1234	73	8	a	a	DET
cuesj-1234	73	9	diluting	diluting	ADJ
cuesj-1234	73	10	agent	agent	NOUN
cuesj-1234	73	11	for	for	ADP
cuesj-1234	73	12	the	the	DET
cuesj-1234	73	13	linear	linear	ADJ
cuesj-1234	73	14	dilution	dilution	NOUN
cuesj-1234	73	15	process	process	NOUN
cuesj-1234	73	16	.	.	PUNCT
cuesj-1234	74	1	for	for	ADP
cuesj-1234	74	2	this	this	DET
cuesj-1234	74	3	process	process	NOUN
cuesj-1234	74	4	,	,	PUNCT
cuesj-1234	74	5	1	1	NUM
cuesj-1234	74	6	ml	ml	NOUN
cuesj-1234	74	7	of	of	ADP
cuesj-1234	74	8	stock	stock	NOUN
cuesj-1234	74	9	solution	solution	NOUN
cuesj-1234	74	10	was	be	AUX
cuesj-1234	74	11	poured	pour	VERB
cuesj-1234	74	12	into	into	ADP
cuesj-1234	74	13	a	a	DET
cuesj-1234	74	14	10	10	NUM
cuesj-1234	74	15	-	-	PUNCT
cuesj-1234	74	16	ml	ml	NOUN
cuesj-1234	74	17	volumetric	volumetric	NOUN
cuesj-1234	74	18	flask	flask	NOUN
cuesj-1234	74	19	using	use	VERB
cuesj-1234	74	20	a	a	DET
cuesj-1234	74	21	pipette	pipette	NOUN
cuesj-1234	74	22	and	and	CCONJ
cuesj-1234	74	23	then	then	ADV
cuesj-1234	74	24	diluted	dilute	VERB
cuesj-1234	74	25	to	to	ADP
cuesj-1234	74	26	10	10	NUM
cuesj-1234	74	27	ml	ml	NOUN
cuesj-1234	74	28	using	use	VERB
cuesj-1234	74	29	the	the	DET
cuesj-1234	74	30	dilution	dilution	NOUN
cuesj-1234	74	31	agent	agent	NOUN
cuesj-1234	74	32	.	.	PUNCT
cuesj-1234	75	1	this	this	PRON
cuesj-1234	75	2	gave	give	VERB
cuesj-1234	75	3	a	a	DET
cuesj-1234	75	4	concentration	concentration	NOUN
cuesj-1234	75	5	of	of	ADP
cuesj-1234	75	6	10	10	NUM
cuesj-1234	75	7	µg	µg	NOUN
cuesj-1234	75	8	/	/	SYM
cuesj-1234	75	9	ml	ml	NOUN
cuesj-1234	75	10	(	(	PUNCT
cuesj-1234	75	11	flask	flask	NOUN
cuesj-1234	75	12	1	1	NUM
cuesj-1234	75	13	)	)	PUNCT
cuesj-1234	75	14	.	.	PUNCT
cuesj-1234	76	1	flask	flask	NOUN
cuesj-1234	76	2	2	2	NUM
cuesj-1234	76	3	had	have	VERB
cuesj-1234	76	4	1.5	1.5	NUM
cuesj-1234	76	5	ml	ml	NOUN
cuesj-1234	76	6	of	of	ADP
cuesj-1234	76	7	the	the	DET
cuesj-1234	76	8	stock	stock	NOUN
cuesj-1234	76	9	solution	solution	NOUN
cuesj-1234	76	10	and	and	CCONJ
cuesj-1234	76	11	was	be	AUX
cuesj-1234	76	12	also	also	ADV
cuesj-1234	76	13	diluted	dilute	VERB
cuesj-1234	76	14	to	to	ADP
cuesj-1234	76	15	10	10	NUM
cuesj-1234	76	16	ml	ml	NOUN
cuesj-1234	76	17	with	with	ADP
cuesj-1234	76	18	the	the	DET
cuesj-1234	76	19	diluting	dilute	VERB
cuesj-1234	76	20	agent	agent	NOUN
cuesj-1234	76	21	,	,	PUNCT
cuesj-1234	76	22	to	to	PART
cuesj-1234	76	23	produce	produce	VERB
cuesj-1234	76	24	a	a	DET
cuesj-1234	76	25	flask	flask	NOUN
cuesj-1234	76	26	of	of	ADP
cuesj-1234	76	27	15	15	NUM
cuesj-1234	76	28	µg	µg	NOUN
cuesj-1234	76	29	/	/	SYM
cuesj-1234	76	30	ml	ml	NOUN
cuesj-1234	76	31	.	.	PUNCT
cuesj-1234	77	1	this	this	DET
cuesj-1234	77	2	process	process	NOUN
cuesj-1234	77	3	was	be	AUX
cuesj-1234	77	4	repeated	repeat	VERB
cuesj-1234	77	5	until	until	SCONJ
cuesj-1234	77	6	concentrations	concentration	NOUN
cuesj-1234	77	7	of	of	ADP
cuesj-1234	77	8	10	10	NUM
cuesj-1234	77	9	,	,	PUNCT
cuesj-1234	77	10	15	15	NUM
cuesj-1234	77	11	,	,	PUNCT
cuesj-1234	77	12	20	20	NUM
cuesj-1234	77	13	,	,	PUNCT
cuesj-1234	77	14	25	25	NUM
cuesj-1234	77	15	,	,	PUNCT
cuesj-1234	77	16	30	30	NUM
cuesj-1234	77	17	,	,	PUNCT
cuesj-1234	77	18	and	and	CCONJ
cuesj-1234	77	19	35	35	NUM
cuesj-1234	77	20	µg	µg	NOUN
cuesj-1234	77	21	/	/	SYM
cuesj-1234	77	22	ml	ml	NOUN
cuesj-1234	77	23	were	be	AUX
cuesj-1234	77	24	made	make	VERB
cuesj-1234	77	25	.	.	PUNCT
cuesj-1234	78	1	a	a	DET
cuesj-1234	78	2	saturated	saturate	VERB
cuesj-1234	78	3	solution	solution	NOUN
cuesj-1234	78	4	of	of	ADP
cuesj-1234	78	5	simvastatin	simvastatin	NOUN
cuesj-1234	78	6	was	be	AUX
cuesj-1234	78	7	also	also	ADV
cuesj-1234	78	8	made	make	VERB
cuesj-1234	78	9	by	by	ADP
cuesj-1234	78	10	adding	add	VERB
cuesj-1234	78	11	10	10	NUM
cuesj-1234	78	12	ml	ml	NOUN
cuesj-1234	78	13	of	of	ADP
cuesj-1234	78	14	distilled	distil	VERB
cuesj-1234	78	15	water	water	NOUN
cuesj-1234	78	16	to	to	ADP
cuesj-1234	78	17	a	a	DET
cuesj-1234	78	18	small	small	ADJ
cuesj-1234	78	19	beaker	beaker	NOUN
cuesj-1234	78	20	,	,	PUNCT
cuesj-1234	78	21	where	where	SCONJ
cuesj-1234	78	22	a	a	DET
cuesj-1234	78	23	magnetic	magnetic	ADJ
cuesj-1234	78	24	stirrer	stirrer	NOUN
cuesj-1234	78	25	was	be	AUX
cuesj-1234	78	26	added	add	VERB
cuesj-1234	78	27	at	at	ADP
cuesj-1234	78	28	900	900	NUM
cuesj-1234	78	29	rotations	rotation	NOUN
cuesj-1234	78	30	.	.	PUNCT
cuesj-1234	79	1	then	then	ADV
cuesj-1234	79	2	,	,	PUNCT
cuesj-1234	79	3	simvastatin	simvastatin	ADJ
cuesj-1234	79	4	powder	powder	NOUN
cuesj-1234	79	5	was	be	AUX
cuesj-1234	79	6	slowly	slowly	ADV
cuesj-1234	79	7	added	add	VERB
cuesj-1234	79	8	until	until	ADP
cuesj-1234	79	9	saturation	saturation	NOUN
cuesj-1234	79	10	,	,	PUNCT
cuesj-1234	79	11	which	which	PRON
cuesj-1234	79	12	was	be	AUX
cuesj-1234	79	13	evident	evident	ADJ
cuesj-1234	79	14	by	by	ADP
cuesj-1234	79	15	a	a	DET
cuesj-1234	79	16	turbid	turbid	ADJ
cuesj-1234	79	17	solution	solution	NOUN
cuesj-1234	79	18	and	and	CCONJ
cuesj-1234	79	19	a	a	DET
cuesj-1234	79	20	persistent	persistent	ADJ
cuesj-1234	79	21	powder	powder	NOUN
cuesj-1234	79	22	being	be	AUX
cuesj-1234	79	23	present	present	ADJ
cuesj-1234	79	24	on	on	ADP
cuesj-1234	79	25	the	the	DET
cuesj-1234	79	26	bottom	bottom	NOUN
cuesj-1234	79	27	of	of	ADP
cuesj-1234	79	28	the	the	DET
cuesj-1234	79	29	container	container	NOUN
cuesj-1234	79	30	.	.	PUNCT
cuesj-1234	80	1	the	the	DET
cuesj-1234	80	2	filter	filter	NOUN
cuesj-1234	80	3	paper	paper	NOUN
cuesj-1234	80	4	was	be	AUX
cuesj-1234	80	5	used	use	VERB
cuesj-1234	80	6	to	to	PART
cuesj-1234	80	7	strain	strain	VERB
cuesj-1234	80	8	the	the	DET
cuesj-1234	80	9	solution	solution	NOUN
cuesj-1234	80	10	,	,	PUNCT
cuesj-1234	80	11	and	and	CCONJ
cuesj-1234	80	12	it	it	PRON
cuesj-1234	80	13	was	be	AUX
cuesj-1234	80	14	measured	measure	VERB
cuesj-1234	80	15	in	in	ADP
cuesj-1234	80	16	a	a	DET
cuesj-1234	80	17	quartz	quartz	NOUN
cuesj-1234	80	18	cuvette	cuvette	NOUN
cuesj-1234	80	19	in	in	ADP
cuesj-1234	80	20	the	the	DET
cuesj-1234	80	21	spectrophotometer	spectrophotometer	NOUN
cuesj-1234	80	22	.	.	PUNCT
cuesj-1234	81	1	the	the	DET
cuesj-1234	81	2	spectrophotometer	spectrophotometer	NOUN
cuesj-1234	81	3	was	be	AUX
cuesj-1234	81	4	calibrated	calibrate	VERB
cuesj-1234	81	5	by	by	ADP
cuesj-1234	81	6	setting	set	VERB
cuesj-1234	81	7	the	the	DET
cuesj-1234	81	8	device	device	NOUN
cuesj-1234	81	9	to	to	PART
cuesj-1234	81	10	scan	scan	VERB
cuesj-1234	81	11	mode	mode	NOUN
cuesj-1234	81	12	from	from	ADP
cuesj-1234	81	13	200	200	NUM
cuesj-1234	81	14	nm	nm	NOUN
cuesj-1234	81	15	to	to	ADP
cuesj-1234	81	16	400	400	NUM
cuesj-1234	81	17	nm	nm	NOUN
cuesj-1234	81	18	and	and	CCONJ
cuesj-1234	81	19	putting	put	VERB
cuesj-1234	81	20	the	the	DET
cuesj-1234	81	21	diluting	dilute	VERB
cuesj-1234	81	22	agent	agent	NOUN
cuesj-1234	81	23	as	as	ADP
cuesj-1234	81	24	the	the	DET
cuesj-1234	81	25	test	test	NOUN
cuesj-1234	81	26	sample	sample	NOUN
cuesj-1234	81	27	to	to	PART
cuesj-1234	81	28	form	form	VERB
cuesj-1234	81	29	the	the	DET
cuesj-1234	81	30	reference	reference	NOUN
cuesj-1234	81	31	and	and	CCONJ
cuesj-1234	81	32	cancel	cancel	VERB
cuesj-1234	81	33	all	all	DET
cuesj-1234	81	34	external	external	ADJ
cuesj-1234	81	35	factors	factor	NOUN
cuesj-1234	81	36	.	.	PUNCT
cuesj-1234	82	1	the	the	DET
cuesj-1234	82	2	spectrophotometer	spectrophotometer	NOUN
cuesj-1234	82	3	was	be	AUX
cuesj-1234	82	4	also	also	ADV
cuesj-1234	82	5	used	use	VERB
cuesj-1234	82	6	to	to	PART
cuesj-1234	82	7	create	create	VERB
cuesj-1234	82	8	a	a	DET
cuesj-1234	82	9	wavelength	wavelength	NOUN
cuesj-1234	82	10	intensity	intensity	NOUN
cuesj-1234	82	11	chart	chart	NOUN
cuesj-1234	82	12	from	from	ADP
cuesj-1234	82	13	the	the	DET
cuesj-1234	82	14	saturated	saturate	VERB
cuesj-1234	82	15	simvastatin	simvastatin	NOUN
cuesj-1234	82	16	solution	solution	NOUN
cuesj-1234	82	17	;	;	PUNCT
cuesj-1234	82	18	then	then	ADV
cuesj-1234	82	19	the	the	DET
cuesj-1234	82	20	highest	high	ADJ
cuesj-1234	82	21	peak	peak	NOUN
cuesj-1234	82	22	,	,	PUNCT
cuesj-1234	82	23	at	at	ADP
cuesj-1234	82	24	252	252	NUM
cuesj-1234	82	25	nm	nm	NOUN
cuesj-1234	82	26	,	,	PUNCT
cuesj-1234	82	27	was	be	AUX
cuesj-1234	82	28	chosen	choose	VERB
cuesj-1234	82	29	as	as	ADP
cuesj-1234	82	30	the	the	DET
cuesj-1234	82	31	maximum	maximum	ADJ
cuesj-1234	82	32	wavelength	wavelength	NOUN
cuesj-1234	82	33	(	(	PUNCT
cuesj-1234	82	34	λ	λ	X
cuesj-1234	82	35	max	max	PROPN
cuesj-1234	82	36	)	)	PUNCT
cuesj-1234	82	37	.	.	PUNCT
cuesj-1234	83	1	once	once	ADV
cuesj-1234	83	2	this	this	PRON
cuesj-1234	83	3	was	be	AUX
cuesj-1234	83	4	found	find	VERB
cuesj-1234	83	5	,	,	PUNCT
cuesj-1234	83	6	each	each	PRON
cuesj-1234	83	7	of	of	ADP
cuesj-1234	83	8	the	the	DET
cuesj-1234	83	9	test	test	NOUN
cuesj-1234	83	10	samples	sample	NOUN
cuesj-1234	83	11	of	of	ADP
cuesj-1234	83	12	concentrations	concentration	NOUN
cuesj-1234	83	13	10–35	10–35	NUM
cuesj-1234	83	14	µg	µg	NOUN
cuesj-1234	83	15	/	/	SYM
cuesj-1234	83	16	ml	ml	NOUN
cuesj-1234	83	17	was	be	AUX
cuesj-1234	83	18	measured	measure	VERB
cuesj-1234	83	19	three	three	NUM
cuesj-1234	83	20	times	time	NOUN
cuesj-1234	83	21	and	and	CCONJ
cuesj-1234	83	22	plotted	plot	VERB
cuesj-1234	83	23	.	.	PUNCT
cuesj-1234	84	1	a	a	DET
cuesj-1234	84	2	calibration	calibration	NOUN
cuesj-1234	84	3	curve	curve	NOUN
cuesj-1234	84	4	was	be	AUX
cuesj-1234	84	5	fitted	fit	VERB
cuesj-1234	84	6	to	to	ADP
cuesj-1234	84	7	the	the	DET
cuesj-1234	84	8	plotted	plot	VERB
cuesj-1234	84	9	absorbance	absorbance	NOUN
cuesj-1234	84	10	values	value	NOUN
cuesj-1234	84	11	.	.	PUNCT
cuesj-1234	85	1	after	after	ADP
cuesj-1234	85	2	this	this	DET
cuesj-1234	85	3	plotting	plotting	NOUN
cuesj-1234	85	4	,	,	PUNCT
cuesj-1234	85	5	the	the	DET
cuesj-1234	85	6	absorbance	absorbance	NOUN
cuesj-1234	85	7	of	of	ADP
cuesj-1234	85	8	the	the	DET
cuesj-1234	85	9	saturated	saturate	VERB
cuesj-1234	85	10	simvastatin	simvastatin	NOUN
cuesj-1234	85	11	was	be	AUX
cuesj-1234	85	12	measured	measure	VERB
cuesj-1234	85	13	in	in	ADP
cuesj-1234	85	14	the	the	DET
cuesj-1234	85	15	same	same	ADJ
cuesj-1234	85	16	way	way	NOUN
cuesj-1234	85	17	,	,	PUNCT
cuesj-1234	85	18	and	and	CCONJ
cuesj-1234	85	19	the	the	DET
cuesj-1234	85	20	concentration	concentration	NOUN
cuesj-1234	85	21	was	be	AUX
cuesj-1234	85	22	calculated	calculate	VERB
cuesj-1234	85	23	using	use	VERB
cuesj-1234	85	24	the	the	DET
cuesj-1234	85	25	reverse	reverse	NOUN
cuesj-1234	85	26	of	of	ADP
cuesj-1234	85	27	the	the	DET
cuesj-1234	85	28	calibration	calibration	NOUN
cuesj-1234	85	29	curve	curve	NOUN
cuesj-1234	85	30	equation	equation	NOUN
cuesj-1234	85	31	.	.	PUNCT
cuesj-1234	86	1	the	the	DET
cuesj-1234	86	2	solubility	solubility	NOUN
cuesj-1234	86	3	-	-	PUNCT
cuesj-1234	86	4	modifying	modify	VERB
cuesj-1234	86	5	agents	agent	NOUN
cuesj-1234	86	6	were	be	AUX
cuesj-1234	86	7	l	l	NOUN
cuesj-1234	86	8	-	-	NOUN
cuesj-1234	86	9	isoleucine	isoleucine	ADJ
cuesj-1234	86	10	and	and	CCONJ
cuesj-1234	86	11	sodium	sodium	NOUN
cuesj-1234	86	12	docusate	docusate	NOUN
cuesj-1234	86	13	.	.	PUNCT
cuesj-1234	87	1	in	in	ADP
cuesj-1234	87	2	combining	combine	VERB
cuesj-1234	87	3	them	they	PRON
cuesj-1234	87	4	,	,	PUNCT
cuesj-1234	87	5	the	the	DET
cuesj-1234	87	6	first	first	ADJ
cuesj-1234	87	7	sample	sample	NOUN
cuesj-1234	87	8	was	be	AUX
cuesj-1234	87	9	made	make	VERB
cuesj-1234	87	10	of	of	ADP
cuesj-1234	87	11	1	1	NUM
cuesj-1234	87	12	g	g	NOUN
cuesj-1234	87	13	simvastatin	simvastatin	NOUN
cuesj-1234	87	14	and	and	CCONJ
cuesj-1234	87	15	0.25	0.25	NUM
cuesj-1234	87	16	g	g	NOUN
cuesj-1234	87	17	each	each	PRON
cuesj-1234	87	18	of	of	ADP
cuesj-1234	87	19	sodium	sodium	NOUN
cuesj-1234	87	20	docusate	docusate	NOUN
cuesj-1234	87	21	and	and	CCONJ
cuesj-1234	87	22	isoleucine	isoleucine	NOUN
cuesj-1234	87	23	;	;	PUNCT
cuesj-1234	87	24	the	the	DET
cuesj-1234	87	25	second	second	ADJ
cuesj-1234	87	26	sample	sample	NOUN
cuesj-1234	87	27	was	be	AUX
cuesj-1234	87	28	1	1	NUM
cuesj-1234	87	29	g	g	NOUN
cuesj-1234	87	30	simvastatin	simvastatin	NOUN
cuesj-1234	87	31	and	and	CCONJ
cuesj-1234	87	32	0.5	0.5	NUM
cuesj-1234	87	33	g	g	NOUN
cuesj-1234	87	34	each	each	PRON
cuesj-1234	87	35	of	of	ADP
cuesj-1234	87	36	docusate	docusate	NOUN
cuesj-1234	87	37	and	and	CCONJ
cuesj-1234	87	38	isoleucine	isoleucine	NOUN
cuesj-1234	87	39	,	,	PUNCT
cuesj-1234	87	40	and	and	CCONJ
cuesj-1234	87	41	the	the	DET
cuesj-1234	87	42	third	third	ADJ
cuesj-1234	87	43	sample	sample	NOUN
cuesj-1234	87	44	was	be	AUX
cuesj-1234	87	45	1	1	NUM
cuesj-1234	87	46	g	g	NOUN
cuesj-1234	87	47	simvastatin	simvastatin	NOUN
cuesj-1234	87	48	and	and	CCONJ
cuesj-1234	87	49	0.75	0.75	NUM
cuesj-1234	87	50	g	g	ADP
cuesj-1234	87	51	each	each	PRON
cuesj-1234	87	52	of	of	ADP
cuesj-1234	87	53	docusate	docusate	NOUN
cuesj-1234	87	54	and	and	CCONJ
cuesj-1234	87	55	isoleucine	isoleucine	NOUN
cuesj-1234	87	56	.	.	PUNCT
cuesj-1234	88	1	the	the	DET
cuesj-1234	88	2	combination	combination	NOUN
cuesj-1234	88	3	ratios	ratio	NOUN
cuesj-1234	88	4	are	be	AUX
cuesj-1234	88	5	shown	show	VERB
cuesj-1234	88	6	in	in	ADP
cuesj-1234	88	7	table	table	NOUN
cuesj-1234	88	8	1	1	NUM
cuesj-1234	88	9	.	.	PUNCT
cuesj-1234	89	1	these	these	DET
cuesj-1234	89	2	components	component	NOUN
cuesj-1234	89	3	were	be	AUX
cuesj-1234	89	4	weighed	weigh	VERB
cuesj-1234	89	5	separately	separately	ADV
cuesj-1234	89	6	on	on	ADP
cuesj-1234	89	7	an	an	DET
cuesj-1234	89	8	accurate	accurate	ADJ
cuesj-1234	89	9	scale	scale	NOUN
cuesj-1234	89	10	and	and	CCONJ
cuesj-1234	89	11	then	then	ADV
cuesj-1234	89	12	combined	combine	VERB
cuesj-1234	89	13	in	in	ADP
cuesj-1234	89	14	a	a	DET
cuesj-1234	89	15	mortar	mortar	NOUN
cuesj-1234	89	16	and	and	CCONJ
cuesj-1234	89	17	pestle	pestle	NOUN
cuesj-1234	89	18	.	.	PUNCT
cuesj-1234	90	1	a	a	DET
cuesj-1234	90	2	sufficient	sufficient	ADJ
cuesj-1234	90	3	amount	amount	NOUN
cuesj-1234	90	4	of	of	ADP
cuesj-1234	90	5	ethanol	ethanol	NOUN
cuesj-1234	90	6	was	be	AUX
cuesj-1234	90	7	added	add	VERB
cuesj-1234	90	8	to	to	PART
cuesj-1234	90	9	submerge	submerge	VERB
cuesj-1234	90	10	all	all	DET
cuesj-1234	90	11	the	the	DET
cuesj-1234	90	12	ingredients	ingredient	NOUN
cuesj-1234	90	13	in	in	ADP
cuesj-1234	90	14	the	the	DET
cuesj-1234	90	15	mortar	mortar	NOUN
cuesj-1234	90	16	,	,	PUNCT
cuesj-1234	90	17	where	where	SCONJ
cuesj-1234	90	18	they	they	PRON
cuesj-1234	90	19	were	be	AUX
cuesj-1234	90	20	manually	manually	ADV
cuesj-1234	90	21	levigated	levigate	VERB
cuesj-1234	90	22	until	until	SCONJ
cuesj-1234	90	23	a	a	DET
cuesj-1234	90	24	single	single	ADJ
cuesj-1234	90	25	-	-	PUNCT
cuesj-1234	90	26	phase	phase	NOUN
cuesj-1234	90	27	solution	solution	NOUN
cuesj-1234	90	28	was	be	AUX
cuesj-1234	90	29	formed	form	VERB
cuesj-1234	90	30	for	for	ADP
cuesj-1234	90	31	complete	complete	ADJ
cuesj-1234	90	32	homogenization	homogenization	NOUN
cuesj-1234	90	33	.	.	PUNCT
cuesj-1234	91	1	the	the	DET
cuesj-1234	91	2	samples	sample	NOUN
cuesj-1234	91	3	were	be	AUX
cuesj-1234	91	4	left	leave	VERB
cuesj-1234	91	5	in	in	ADP
cuesj-1234	91	6	a	a	DET
cuesj-1234	91	7	hot	hot	ADJ
cuesj-1234	91	8	air	air	NOUN
cuesj-1234	91	9	oven	oven	NOUN
cuesj-1234	91	10	for	for	ADP
cuesj-1234	91	11	several	several	ADJ
cuesj-1234	91	12	days	day	NOUN
cuesj-1234	91	13	to	to	PART
cuesj-1234	91	14	dry	dry	VERB
cuesj-1234	91	15	,	,	PUNCT
cuesj-1234	91	16	and	and	CCONJ
cuesj-1234	91	17	the	the	DET
cuesj-1234	91	18	dry	dry	ADJ
cuesj-1234	91	19	products	product	NOUN
cuesj-1234	91	20	were	be	AUX
cuesj-1234	91	21	taken	take	VERB
cuesj-1234	91	22	out	out	ADP
cuesj-1234	91	23	and	and	CCONJ
cuesj-1234	91	24	ground	grind	VERB
cuesj-1234	91	25	into	into	ADP
cuesj-1234	91	26	a	a	DET
cuesj-1234	91	27	powder	powder	NOUN
cuesj-1234	91	28	with	with	ADP
cuesj-1234	91	29	a	a	DET
cuesj-1234	91	30	pestle	pestle	NOUN
cuesj-1234	91	31	.	.	PUNCT
cuesj-1234	92	1	these	these	DET
cuesj-1234	92	2	products	product	NOUN
cuesj-1234	92	3	were	be	AUX
cuesj-1234	92	4	made	make	VERB
cuesj-1234	92	5	to	to	PART
cuesj-1234	92	6	be	be	AUX
cuesj-1234	92	7	incorporated	incorporate	VERB
cuesj-1234	92	8	into	into	ADP
cuesj-1234	92	9	modified	modify	VERB
cuesj-1234	92	10	-	-	PUNCT
cuesj-1234	92	11	simvastatin	simvastatin	NOUN
cuesj-1234	92	12	solutions	solution	NOUN
cuesj-1234	92	13	.	.	PUNCT
cuesj-1234	93	1	the	the	DET
cuesj-1234	93	2	modified	modify	VERB
cuesj-1234	93	3	solutions	solution	NOUN
cuesj-1234	93	4	were	be	AUX
cuesj-1234	93	5	prepared	prepare	VERB
cuesj-1234	93	6	by	by	ADP
cuesj-1234	93	7	adding	add	VERB
cuesj-1234	93	8	10	10	NUM
cuesj-1234	93	9	ml	ml	NOUN
cuesj-1234	93	10	of	of	ADP
cuesj-1234	93	11	distilled	distil	VERB
cuesj-1234	93	12	water	water	NOUN
cuesj-1234	93	13	in	in	ADP
cuesj-1234	93	14	a	a	DET
cuesj-1234	93	15	small	small	ADJ
cuesj-1234	93	16	20	20	NUM
cuesj-1234	93	17	-	-	PUNCT
cuesj-1234	93	18	ml	ml	NOUN
cuesj-1234	93	19	beaker	beaker	NOUN
cuesj-1234	93	20	and	and	CCONJ
cuesj-1234	93	21	placing	place	VERB
cuesj-1234	93	22	it	it	PRON
cuesj-1234	93	23	on	on	ADP
cuesj-1234	93	24	the	the	DET
cuesj-1234	93	25	magnetic	magnetic	ADJ
cuesj-1234	93	26	stirrer	stirrer	ADJ
cuesj-1234	93	27	plate	plate	NOUN
cuesj-1234	93	28	,	,	PUNCT
cuesj-1234	93	29	while	while	SCONJ
cuesj-1234	93	30	small	small	ADJ
cuesj-1234	93	31	amounts	amount	NOUN
cuesj-1234	93	32	of	of	ADP
cuesj-1234	93	33	the	the	DET
cuesj-1234	93	34	powdered	powdered	ADJ
cuesj-1234	93	35	product	product	NOUN
cuesj-1234	93	36	were	be	AUX
cuesj-1234	93	37	added	add	VERB
cuesj-1234	93	38	to	to	ADP
cuesj-1234	93	39	it	it	PRON
cuesj-1234	93	40	until	until	ADP
cuesj-1234	93	41	saturation	saturation	NOUN
cuesj-1234	93	42	.	.	PUNCT
cuesj-1234	94	1	it	it	PRON
cuesj-1234	94	2	was	be	AUX
cuesj-1234	94	3	kept	keep	VERB
cuesj-1234	94	4	at	at	ADP
cuesj-1234	94	5	900	900	NUM
cuesj-1234	94	6	rpm	rpm	NOUN
cuesj-1234	94	7	for	for	ADP
cuesj-1234	94	8	10	10	NUM
cuesj-1234	94	9	-	-	PUNCT
cuesj-1234	94	10	min	min	NOUN
cuesj-1234	94	11	intervals	interval	NOUN
cuesj-1234	94	12	until	until	SCONJ
cuesj-1234	94	13	there	there	PRON
cuesj-1234	94	14	was	be	VERB
cuesj-1234	94	15	evident	evident	ADJ
cuesj-1234	94	16	precipitation	precipitation	NOUN
cuesj-1234	94	17	.	.	PUNCT
cuesj-1234	95	1	finally	finally	ADV
cuesj-1234	95	2	,	,	PUNCT
cuesj-1234	95	3	filter	filter	NOUN
cuesj-1234	95	4	paper	paper	NOUN
cuesj-1234	95	5	was	be	AUX
cuesj-1234	95	6	used	use	VERB
cuesj-1234	95	7	on	on	ADP
cuesj-1234	95	8	the	the	DET
cuesj-1234	95	9	solution	solution	NOUN
cuesj-1234	95	10	,	,	PUNCT
cuesj-1234	95	11	and	and	CCONJ
cuesj-1234	95	12	it	it	PRON
cuesj-1234	95	13	was	be	AUX
cuesj-1234	95	14	put	put	VERB
cuesj-1234	95	15	in	in	ADP
cuesj-1234	95	16	a	a	DET
cuesj-1234	95	17	cuvette	cuvette	NOUN
cuesj-1234	95	18	to	to	PART
cuesj-1234	95	19	measure	measure	VERB
cuesj-1234	95	20	with	with	ADP
cuesj-1234	95	21	a	a	DET
cuesj-1234	95	22	spectrophotometer	spectrophotometer	NOUN
cuesj-1234	95	23	,	,	PUNCT
cuesj-1234	95	24	where	where	SCONJ
cuesj-1234	95	25	the	the	DET
cuesj-1234	95	26	reading	reading	NOUN
cuesj-1234	95	27	was	be	AUX
cuesj-1234	95	28	repeated	repeat	VERB
cuesj-1234	95	29	3	3	NUM
cuesj-1234	95	30	times	time	NOUN
cuesj-1234	95	31	.	.	PUNCT
cuesj-1234	96	1	this	this	PRON
cuesj-1234	96	2	was	be	AUX
cuesj-1234	96	3	done	do	VERB
cuesj-1234	96	4	for	for	ADP
cuesj-1234	96	5	all	all	DET
cuesj-1234	96	6	products	product	NOUN
cuesj-1234	96	7	before	before	ADP
cuesj-1234	96	8	the	the	DET
cuesj-1234	96	9	final	final	ADJ
cuesj-1234	96	10	absorbance	absorbance	NOUN
cuesj-1234	96	11	measurements	measurement	NOUN
cuesj-1234	96	12	.	.	PUNCT
cuesj-1234	97	1	results	result	NOUN
cuesj-1234	97	2	and	and	CCONJ
cuesj-1234	97	3	discussion	discussion	NOUN
cuesj-1234	97	4	results	result	VERB
cuesj-1234	97	5	the	the	DET
cuesj-1234	97	6	results	result	NOUN
cuesj-1234	97	7	of	of	ADP
cuesj-1234	97	8	the	the	DET
cuesj-1234	97	9	calibration	calibration	NOUN
cuesj-1234	97	10	curve	curve	NOUN
cuesj-1234	97	11	are	be	AUX
cuesj-1234	97	12	shown	show	VERB
cuesj-1234	97	13	in	in	ADP
cuesj-1234	97	14	table	table	NOUN
cuesj-1234	97	15	2	2	NUM
cuesj-1234	97	16	.	.	PUNCT
cuesj-1234	98	1	the	the	DET
cuesj-1234	98	2	recorded	record	VERB
cuesj-1234	98	3	absorbance	absorbance	NOUN
cuesj-1234	98	4	values	value	NOUN
cuesj-1234	98	5	shown	show	VERB
cuesj-1234	98	6	in	in	ADP
cuesj-1234	98	7	table	table	NOUN
cuesj-1234	98	8	2	2	NUM
cuesj-1234	98	9	were	be	AUX
cuesj-1234	98	10	plotted	plot	VERB
cuesj-1234	98	11	to	to	PART
cuesj-1234	98	12	get	get	VERB
cuesj-1234	98	13	the	the	DET
cuesj-1234	98	14	best	well	ADV
cuesj-1234	98	15	-	-	PUNCT
cuesj-1234	98	16	fitting	fit	VERB
cuesj-1234	98	17	curve	curve	NOUN
cuesj-1234	98	18	presented	present	VERB
cuesj-1234	98	19	in	in	ADP
cuesj-1234	98	20	figure	figure	NOUN
cuesj-1234	98	21	7	7	NUM
cuesj-1234	98	22	.	.	PUNCT
cuesj-1234	99	1	the	the	DET
cuesj-1234	99	2	fitting	fitting	ADJ
cuesj-1234	99	3	curve	curve	NOUN
cuesj-1234	99	4	represents	represent	VERB
cuesj-1234	99	5	the	the	DET
cuesj-1234	99	6	actual	actual	ADJ
cuesj-1234	99	7	values	value	NOUN
cuesj-1234	99	8	with	with	ADP
cuesj-1234	99	9	an	an	DET
cuesj-1234	99	10	equation	equation	NOUN
cuesj-1234	99	11	of	of	ADP
cuesj-1234	99	12	y	y	PROPN
cuesj-1234	99	13	=	=	SYM
cuesj-1234	99	14	0.00303x-0.00051	0.00303x-0.00051	PROPN
cuesj-1234	99	15	which	which	PRON
cuesj-1234	99	16	relates	relate	VERB
cuesj-1234	99	17	absorbance	absorbance	NOUN
cuesj-1234	99	18	with	with	ADP
cuesj-1234	99	19	concentration	concentration	NOUN
cuesj-1234	99	20	,	,	PUNCT
cuesj-1234	99	21	where	where	SCONJ
cuesj-1234	99	22	y	y	PROPN
cuesj-1234	99	23	is	be	AUX
cuesj-1234	99	24	the	the	DET
cuesj-1234	99	25	absorbance	absorbance	NOUN
cuesj-1234	99	26	and	and	CCONJ
cuesj-1234	99	27	x	x	NOUN
cuesj-1234	99	28	is	be	AUX
cuesj-1234	99	29	the	the	DET
cuesj-1234	99	30	concentration	concentration	NOUN
cuesj-1234	99	31	.	.	PUNCT
cuesj-1234	100	1	when	when	SCONJ
cuesj-1234	100	2	mathematically	mathematically	ADV
cuesj-1234	100	3	reversed	reverse	VERB
cuesj-1234	100	4	,	,	PUNCT
cuesj-1234	100	5	the	the	DET
cuesj-1234	100	6	equation	equation	NOUN
cuesj-1234	100	7	of	of	ADP
cuesj-1234	100	8	best	good	ADJ
cuesj-1234	100	9	fit	fit	NOUN
cuesj-1234	100	10	can	can	AUX
cuesj-1234	100	11	form	form	VERB
cuesj-1234	100	12	a	a	DET
cuesj-1234	100	13	new	new	ADJ
cuesj-1234	100	14	equation	equation	NOUN
cuesj-1234	100	15	,	,	PUNCT
cuesj-1234	100	16	which	which	PRON
cuesj-1234	100	17	is	be	AUX
cuesj-1234	100	18	written	write	VERB
cuesj-1234	100	19	as	as	ADP
cuesj-1234	100	20	+	+	NOUN
cuesj-1234	100	21	=	=	SYM
cuesj-1234	100	22	0.00051	0.00051	NUM
cuesj-1234	100	23	0.00303	0.00303	NUM
cuesj-1234	100	24	y	y	NOUN
cuesj-1234	100	25	x	x	PUNCT
cuesj-1234	100	26	,	,	PUNCT
cuesj-1234	100	27	and	and	CCONJ
cuesj-1234	100	28	it	it	PRON
cuesj-1234	100	29	can	can	AUX
cuesj-1234	100	30	be	be	AUX
cuesj-1234	100	31	used	use	VERB
cuesj-1234	100	32	to	to	PART
cuesj-1234	100	33	find	find	VERB
cuesj-1234	100	34	the	the	DET
cuesj-1234	100	35	concentration	concentration	NOUN
cuesj-1234	100	36	of	of	ADP
cuesj-1234	100	37	the	the	DET
cuesj-1234	100	38	saturated	saturate	VERB
cuesj-1234	100	39	simvastatin	simvastatin	ADJ
cuesj-1234	100	40	solution	solution	NOUN
cuesj-1234	100	41	from	from	ADP
cuesj-1234	100	42	absorbance	absorbance	NOUN
cuesj-1234	100	43	,	,	PUNCT
cuesj-1234	100	44	as	as	SCONJ
cuesj-1234	100	45	shown	show	VERB
cuesj-1234	100	46	in	in	ADP
cuesj-1234	100	47	table	table	NOUN
cuesj-1234	100	48	3	3	NUM
cuesj-1234	100	49	.	.	PUNCT
cuesj-1234	100	50	table	table	NOUN
cuesj-1234	100	51	4	4	NUM
cuesj-1234	100	52	contains	contain	VERB
cuesj-1234	100	53	the	the	DET
cuesj-1234	100	54	results	result	NOUN
cuesj-1234	100	55	of	of	ADP
cuesj-1234	100	56	the	the	DET
cuesj-1234	100	57	absorbances	absorbance	NOUN
cuesj-1234	100	58	and	and	CCONJ
cuesj-1234	100	59	solubilities	solubility	NOUN
cuesj-1234	100	60	of	of	ADP
cuesj-1234	100	61	the	the	DET
cuesj-1234	100	62	simvastatin	simvastatin	NOUN
cuesj-1234	100	63	:	:	PUNCT
cuesj-1234	100	64	docusate	docusate	NOUN
cuesj-1234	100	65	:	:	PUNCT
cuesj-1234	100	66	isoleucine	isoleucine	NOUN
cuesj-1234	100	67	solid	solid	ADJ
cuesj-1234	100	68	dispersion	dispersion	NOUN
cuesj-1234	100	69	mixtures	mixture	NOUN
cuesj-1234	100	70	.	.	PUNCT
cuesj-1234	101	1	the	the	DET
cuesj-1234	101	2	solubility	solubility	NOUN
cuesj-1234	101	3	of	of	ADP
cuesj-1234	101	4	sample	sample	NOUN
cuesj-1234	101	5	1	1	NUM
cuesj-1234	101	6	,	,	PUNCT
cuesj-1234	101	7	sample	sample	NOUN
cuesj-1234	101	8	2	2	NUM
cuesj-1234	101	9	,	,	PUNCT
cuesj-1234	101	10	and	and	CCONJ
cuesj-1234	101	11	sample	sample	NOUN
cuesj-1234	101	12	3	3	NUM
cuesj-1234	101	13	was	be	AUX
cuesj-1234	101	14	increased	increase	VERB
cuesj-1234	101	15	1.5	1.5	NUM
cuesj-1234	101	16	-	-	NUM
cuesj-1234	101	17	fold	fold	ADJ
cuesj-1234	101	18	,	,	PUNCT
cuesj-1234	101	19	7.18	7.18	NUM
cuesj-1234	101	20	-	-	NOUN
cuesj-1234	101	21	fold	fold	ADJ
cuesj-1234	101	22	,	,	PUNCT
cuesj-1234	101	23	and	and	CCONJ
cuesj-1234	101	24	4.8	4.8	NUM
cuesj-1234	101	25	-	-	NUM
cuesj-1234	101	26	fold	fold	ADJ
cuesj-1234	101	27	,	,	PUNCT
cuesj-1234	101	28	respectively	respectively	ADV
cuesj-1234	101	29	,	,	PUNCT
cuesj-1234	101	30	from	from	ADP
cuesj-1234	101	31	the	the	DET
cuesj-1234	101	32	solubility	solubility	NOUN
cuesj-1234	101	33	of	of	ADP
cuesj-1234	101	34	pure	pure	ADJ
cuesj-1234	101	35	simvastatin	simvastatin	PROPN
cuesj-1234	101	36	.	.	PUNCT
cuesj-1234	102	1	discussion	discussion	NOUN
cuesj-1234	102	2	the	the	DET
cuesj-1234	102	3	smallest	small	ADJ
cuesj-1234	102	4	concentration	concentration	NOUN
cuesj-1234	102	5	of	of	ADP
cuesj-1234	102	6	1	1	NUM
cuesj-1234	102	7	g	g	NOUN
cuesj-1234	102	8	simvastatin	simvastatin	NOUN
cuesj-1234	102	9	to	to	ADP
cuesj-1234	102	10	0.25	0.25	NUM
cuesj-1234	102	11	g	g	NOUN
cuesj-1234	102	12	of	of	ADP
cuesj-1234	102	13	excipients	excipient	NOUN
cuesj-1234	102	14	yielded	yield	VERB
cuesj-1234	102	15	the	the	DET
cuesj-1234	102	16	smallest	small	ADJ
cuesj-1234	102	17	improvement	improvement	NOUN
cuesj-1234	102	18	of	of	ADP
cuesj-1234	102	19	only	only	ADV
cuesj-1234	102	20	1.5	1.5	NUM
cuesj-1234	102	21	-	-	NUM
cuesj-1234	102	22	fold	fold	ADJ
cuesj-1234	102	23	.	.	PUNCT
cuesj-1234	103	1	table	table	NOUN
cuesj-1234	103	2	1	1	NUM
cuesj-1234	103	3	:	:	PUNCT
cuesj-1234	103	4	excipient	excipient	ADJ
cuesj-1234	103	5	ratios	ratio	NOUN
cuesj-1234	103	6	sample	sample	PROPN
cuesj-1234	103	7	simva.(g	simva.(g	PROPN
cuesj-1234	103	8	)	)	PUNCT
cuesj-1234	103	9	docus.(g	docus.(g	PROPN
cuesj-1234	103	10	)	)	PUNCT
cuesj-1234	103	11	isoleuc.(g	isoleuc.(g	PROPN
cuesj-1234	103	12	)	)	PUNCT
cuesj-1234	103	13	ratio	ratio	NOUN
cuesj-1234	103	14	s1	s1	NOUN
cuesj-1234	103	15	1	1	NUM
cuesj-1234	103	16	0.25	0.25	NUM
cuesj-1234	103	17	0.25	0.25	NUM
cuesj-1234	103	18	4:1:1	4:1:1	PROPN
cuesj-1234	103	19	s2	s2	NOUN
cuesj-1234	103	20	1	1	NUM
cuesj-1234	103	21	0.50	0.50	NUM
cuesj-1234	103	22	0.50	0.50	NUM
cuesj-1234	103	23	2:1:1	2:1:1	NUM
cuesj-1234	103	24	s3	s3	PROPN
cuesj-1234	103	25	1	1	NUM
cuesj-1234	103	26	0.75	0.75	NUM
cuesj-1234	103	27	0.75	0.75	NUM
cuesj-1234	103	28	4:3:3	4:3:3	NUM
cuesj-1234	103	29	table	table	NOUN
cuesj-1234	103	30	2	2	NUM
cuesj-1234	103	31	:	:	PUNCT
cuesj-1234	103	32	simvastatin	simvastatin	ADJ
cuesj-1234	103	33	absorbances	absorbance	NOUN
cuesj-1234	103	34	conc	conc	VERB
cuesj-1234	103	35	.	.	PUNCT
cuesj-1234	104	1	(	(	PUNCT
cuesj-1234	104	2	µg	µg	NOUN
cuesj-1234	104	3	)	)	PUNCT
cuesj-1234	104	4	abs	ab	NOUN
cuesj-1234	104	5	.	.	PUNCT
cuesj-1234	105	1	1	1	NUM
cuesj-1234	105	2	abs	ab	NOUN
cuesj-1234	105	3	.	.	PUNCT
cuesj-1234	105	4	2	2	NUM
cuesj-1234	105	5	abs	ab	NOUN
cuesj-1234	105	6	.	.	PUNCT
cuesj-1234	105	7	3	3	NUM
cuesj-1234	105	8	avg	avg	NOUN
cuesj-1234	105	9	.	.	PUNCT
cuesj-1234	105	10	abs	abs	PROPN
cuesj-1234	105	11	.	.	PUNCT
cuesj-1234	106	1	10	10	NUM
cuesj-1234	106	2	0.0280	0.0280	NUM
cuesj-1234	106	3	0.0305	0.0305	NUM
cuesj-1234	106	4	0.0258	0.0258	NUM
cuesj-1234	106	5	0.0281	0.0281	NUM
cuesj-1234	106	6	15	15	NUM
cuesj-1234	106	7	0.0448	0.0448	NUM
cuesj-1234	106	8	0.0448	0.0448	NUM
cuesj-1234	106	9	0.0446	0.0446	NUM
cuesj-1234	106	10	0.0447	0.0447	NUM
cuesj-1234	106	11	20	20	NUM
cuesj-1234	106	12	0.0595	0.0595	NUM
cuesj-1234	106	13	0.0645	0.0645	NUM
cuesj-1234	107	1	0.0623	0.0623	NUM
cuesj-1234	107	2	0.0621	0.0621	NUM
cuesj-1234	107	3	25	25	NUM
cuesj-1234	107	4	0.0788	0.0788	NUM
cuesj-1234	107	5	0.0802	0.0802	NUM
cuesj-1234	107	6	0.0757	0.0757	NUM
cuesj-1234	107	7	0.0782	0.0782	NUM
cuesj-1234	107	8	30	30	NUM
cuesj-1234	107	9	0.0881	0.0881	NUM
cuesj-1234	107	10	0.0858	0.0858	NUM
cuesj-1234	107	11	0.0874	0.0874	NUM
cuesj-1234	107	12	0.0871	0.0871	NUM
cuesj-1234	107	13	35	35	NUM
cuesj-1234	107	14	0.1060	0.1060	NUM
cuesj-1234	107	15	0.1035	0.1035	NUM
cuesj-1234	107	16	0.1068	0.1068	NUM
cuesj-1234	107	17	0.1054	0.1054	NUM
cuesj-1234	107	18	table	table	NOUN
cuesj-1234	107	19	3	3	NUM
cuesj-1234	107	20	:	:	PUNCT
cuesj-1234	107	21	saturated	saturate	VERB
cuesj-1234	107	22	simvastatin	simvastatin	ADJ
cuesj-1234	107	23	abs	ab	NOUN
cuesj-1234	107	24	.	.	PUNCT
cuesj-1234	108	1	1	1	NUM
cuesj-1234	108	2	abs	ab	NOUN
cuesj-1234	108	3	.	.	PUNCT
cuesj-1234	108	4	2	2	NUM
cuesj-1234	108	5	abs	ab	NOUN
cuesj-1234	108	6	.	.	PUNCT
cuesj-1234	108	7	3	3	NUM
cuesj-1234	108	8	avg	avg	PROPN
cuesj-1234	108	9	.	.	PUNCT
cuesj-1234	108	10	abs	ab	NOUN
cuesj-1234	108	11	.	.	PUNCT
cuesj-1234	109	1	conc	conc	NOUN
cuesj-1234	109	2	(	(	PUNCT
cuesj-1234	109	3	µg	µg	NOUN
cuesj-1234	109	4	/	/	SYM
cuesj-1234	109	5	ml	ml	NOUN
cuesj-1234	109	6	)	)	PUNCT
cuesj-1234	109	7	0.1969	0.1969	NUM
cuesj-1234	109	8	0.1979	0.1979	NUM
cuesj-1234	109	9	0.1954	0.1954	NUM
cuesj-1234	109	10	0.1967	0.1967	NUM
cuesj-1234	109	11	65.085	65.085	NUM
cuesj-1234	109	12	al	al	PROPN
cuesj-1234	109	13	-	-	PUNCT
cuesj-1234	109	14	jumaili	jumaili	NOUN
cuesj-1234	109	15	,	,	PUNCT
cuesj-1234	109	16	et	et	PROPN
cuesj-1234	109	17	al	al	PROPN
cuesj-1234	109	18	.	.	PROPN
cuesj-1234	109	19	:	:	PUNCT
cuesj-1234	110	1	enhancing	enhance	VERB
cuesj-1234	110	2	solubility	solubility	NOUN
cuesj-1234	110	3	of	of	ADP
cuesj-1234	110	4	simvastatin	simvastatin	NOUN
cuesj-1234	110	5	with	with	ADP
cuesj-1234	110	6	l	l	NOUN
cuesj-1234	110	7	-	-	NOUN
cuesj-1234	110	8	isoleucine	isoleucine	ADJ
cuesj-1234	110	9	and	and	CCONJ
cuesj-1234	110	10	sodium	sodium	NOUN
cuesj-1234	110	11	docusate	docusate	NOUN
cuesj-1234	110	12	30	30	NUM
cuesj-1234	110	13	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	110	14	cuesj	cuesj	NOUN
cuesj-1234	110	15	2025	2025	NUM
cuesj-1234	110	16	,	,	PUNCT
cuesj-1234	110	17	9	9	NUM
cuesj-1234	110	18	(	(	PUNCT
cuesj-1234	110	19	2	2	NUM
cuesj-1234	110	20	):	):	PUNCT
cuesj-1234	110	21	26	26	NUM
cuesj-1234	110	22	-	-	SYM
cuesj-1234	110	23	32	32	NUM
cuesj-1234	110	24	table	table	NOUN
cuesj-1234	110	25	4	4	NUM
cuesj-1234	110	26	:	:	PUNCT
cuesj-1234	110	27	simvastatin	simvastatin	PROPN
cuesj-1234	110	28	,	,	PUNCT
cuesj-1234	110	29	docusate	docusate	NOUN
cuesj-1234	110	30	,	,	PUNCT
cuesj-1234	110	31	isoleucine	isoleucine	NOUN
cuesj-1234	110	32	concentration	concentration	NOUN
cuesj-1234	110	33	sample	sample	NOUN
cuesj-1234	110	34	abs	ab	NOUN
cuesj-1234	110	35	.	.	PUNCT
cuesj-1234	111	1	1	1	NUM
cuesj-1234	111	2	abs	ab	NOUN
cuesj-1234	111	3	.	.	PUNCT
cuesj-1234	111	4	2	2	NUM
cuesj-1234	111	5	abs	ab	NOUN
cuesj-1234	111	6	.	.	PUNCT
cuesj-1234	111	7	3	3	NUM
cuesj-1234	111	8	avg	avg	PROPN
cuesj-1234	111	9	.	.	PUNCT
cuesj-1234	111	10	abs	abs	PROPN
cuesj-1234	111	11	.	.	PUNCT
cuesj-1234	112	1	conc.(µg	conc.(µg	PROPN
cuesj-1234	112	2	/	/	SYM
cuesj-1234	112	3	ml	ml	NOUN
cuesj-1234	112	4	)	)	PUNCT
cuesj-1234	112	5	1	1	NUM
cuesj-1234	112	6	0.293	0.293	NUM
cuesj-1234	112	7	0.296	0.296	NUM
cuesj-1234	112	8	0.294	0.294	NUM
cuesj-1234	112	9	0.294	0.294	NUM
cuesj-1234	112	10	97.495	97.495	NUM
cuesj-1234	112	11	2	2	NUM
cuesj-1234	112	12	1.447	1.447	NUM
cuesj-1234	112	13	1.408	1.408	NUM
cuesj-1234	112	14	1.392	1.392	NUM
cuesj-1234	112	15	1.416	1.416	NUM
cuesj-1234	112	16	467.53	467.53	NUM
cuesj-1234	112	17	3	3	NUM
cuesj-1234	112	18	0.943	0.943	NUM
cuesj-1234	112	19	0.948	0.948	NUM
cuesj-1234	112	20	0.949	0.949	NUM
cuesj-1234	112	21	0.947	0.947	NUM
cuesj-1234	112	22	312.78	312.78	NUM
cuesj-1234	112	23	a	a	DET
cuesj-1234	112	24	possible	possible	ADJ
cuesj-1234	112	25	theory	theory	NOUN
cuesj-1234	112	26	could	could	AUX
cuesj-1234	112	27	be	be	AUX
cuesj-1234	112	28	that	that	SCONJ
cuesj-1234	112	29	0.25	0.25	NUM
cuesj-1234	112	30	g	g	NOUN
cuesj-1234	112	31	is	be	AUX
cuesj-1234	112	32	below	below	ADP
cuesj-1234	112	33	the	the	DET
cuesj-1234	112	34	cmc	cmc	NOUN
cuesj-1234	112	35	of	of	ADP
cuesj-1234	112	36	sodium	sodium	NOUN
cuesj-1234	112	37	docusate	docusate	NOUN
cuesj-1234	112	38	,	,	PUNCT
cuesj-1234	112	39	which	which	PRON
cuesj-1234	112	40	would	would	AUX
cuesj-1234	112	41	mean	mean	VERB
cuesj-1234	112	42	it	it	PRON
cuesj-1234	112	43	is	be	AUX
cuesj-1234	112	44	too	too	ADV
cuesj-1234	112	45	low	low	ADJ
cuesj-1234	112	46	to	to	PART
cuesj-1234	112	47	allow	allow	VERB
cuesj-1234	112	48	micelles	micelle	NOUN
cuesj-1234	112	49	to	to	PART
cuesj-1234	112	50	form	form	VERB
cuesj-1234	112	51	.	.	PUNCT
cuesj-1234	113	1	at	at	ADP
cuesj-1234	113	2	this	this	DET
cuesj-1234	113	3	concentration	concentration	NOUN
cuesj-1234	113	4	,	,	PUNCT
cuesj-1234	113	5	there	there	PRON
cuesj-1234	113	6	may	may	AUX
cuesj-1234	113	7	be	be	AUX
cuesj-1234	113	8	only	only	ADV
cuesj-1234	113	9	weak	weak	ADJ
cuesj-1234	113	10	solubilization	solubilization	NOUN
cuesj-1234	113	11	due	due	ADP
cuesj-1234	113	12	to	to	ADP
cuesj-1234	113	13	isoleucine	isoleucine	NOUN
cuesj-1234	113	14	alone	alone	ADJ
cuesj-1234	113	15	or	or	CCONJ
cuesj-1234	113	16	weak	weak	ADJ
cuesj-1234	113	17	anionic	anionic	ADJ
cuesj-1234	113	18	interaction	interaction	NOUN
cuesj-1234	113	19	with	with	ADP
cuesj-1234	113	20	docusate	docusate	NOUN
cuesj-1234	113	21	,	,	PUNCT
cuesj-1234	113	22	without	without	ADP
cuesj-1234	113	23	its	its	PRON
cuesj-1234	113	24	strong	strong	ADJ
cuesj-1234	113	25	surfactant	surfactant	ADJ
cuesj-1234	113	26	properties	property	NOUN
cuesj-1234	113	27	.	.	PUNCT
cuesj-1234	114	1	based	base	VERB
cuesj-1234	114	2	on	on	ADP
cuesj-1234	114	3	the	the	DET
cuesj-1234	114	4	results	result	NOUN
cuesj-1234	114	5	given	give	VERB
cuesj-1234	114	6	,	,	PUNCT
cuesj-1234	114	7	there	there	PRON
cuesj-1234	114	8	seems	seem	VERB
cuesj-1234	114	9	to	to	PART
cuesj-1234	114	10	be	be	AUX
cuesj-1234	114	11	a	a	DET
cuesj-1234	114	12	range	range	NOUN
cuesj-1234	114	13	at	at	ADP
cuesj-1234	114	14	which	which	PRON
cuesj-1234	114	15	the	the	DET
cuesj-1234	114	16	excipients	excipient	NOUN
cuesj-1234	114	17	have	have	VERB
cuesj-1234	114	18	optimal	optimal	ADJ
cuesj-1234	114	19	solubilizing	solubilizing	NOUN
cuesj-1234	114	20	effects	effect	NOUN
cuesj-1234	114	21	,	,	PUNCT
cuesj-1234	114	22	and	and	CCONJ
cuesj-1234	114	23	this	this	PRON
cuesj-1234	114	24	is	be	AUX
cuesj-1234	114	25	at	at	ADP
cuesj-1234	114	26	around	around	ADP
cuesj-1234	114	27	a	a	DET
cuesj-1234	114	28	2:1	2:1	NUM
cuesj-1234	114	29	ratio	ratio	NOUN
cuesj-1234	114	30	with	with	ADP
cuesj-1234	114	31	simvastatin	simvastatin	NOUN
cuesj-1234	114	32	:	:	PUNCT
cuesj-1234	114	33	excipients	excipient	NOUN
cuesj-1234	114	34	.	.	PUNCT
cuesj-1234	115	1	the	the	DET
cuesj-1234	115	2	2:1:1	2:1:1	NUM
cuesj-1234	115	3	sample	sample	NOUN
cuesj-1234	115	4	ratio	ratio	NOUN
cuesj-1234	115	5	showed	show	VERB
cuesj-1234	115	6	a	a	DET
cuesj-1234	115	7	sevenfold	sevenfold	ADJ
cuesj-1234	115	8	improvement	improvement	NOUN
cuesj-1234	115	9	while	while	SCONJ
cuesj-1234	115	10	the	the	DET
cuesj-1234	115	11	4:3:3	4:3:3	NUM
cuesj-1234	115	12	ratio	ratio	NOUN
cuesj-1234	115	13	was	be	AUX
cuesj-1234	115	14	improved	improve	VERB
cuesj-1234	115	15	fivefold	fivefold	ADV
cuesj-1234	115	16	.	.	PUNCT
cuesj-1234	116	1	this	this	PRON
cuesj-1234	116	2	indicates	indicate	VERB
cuesj-1234	116	3	that	that	SCONJ
cuesj-1234	116	4	an	an	DET
cuesj-1234	116	5	excess	excess	NOUN
cuesj-1234	116	6	of	of	ADP
cuesj-1234	116	7	docusate	docusate	NOUN
cuesj-1234	116	8	and	and	CCONJ
cuesj-1234	116	9	isoleucine	isoleucine	NOUN
cuesj-1234	116	10	may	may	AUX
cuesj-1234	116	11	hinder	hinder	VERB
cuesj-1234	116	12	the	the	DET
cuesj-1234	116	13	solubility	solubility	NOUN
cuesj-1234	116	14	process	process	NOUN
cuesj-1234	116	15	.	.	PUNCT
cuesj-1234	117	1	this	this	PRON
cuesj-1234	117	2	could	could	AUX
cuesj-1234	117	3	be	be	AUX
cuesj-1234	117	4	due	due	ADJ
cuesj-1234	117	5	to	to	ADP
cuesj-1234	117	6	interactions	interaction	NOUN
cuesj-1234	117	7	with	with	ADP
cuesj-1234	117	8	the	the	DET
cuesj-1234	117	9	chemical	chemical	ADJ
cuesj-1234	117	10	bonds	bond	NOUN
cuesj-1234	117	11	of	of	ADP
cuesj-1234	117	12	simvastatin	simvastatin	NOUN
cuesj-1234	117	13	or	or	CCONJ
cuesj-1234	117	14	due	due	ADP
cuesj-1234	117	15	to	to	ADP
cuesj-1234	117	16	the	the	DET
cuesj-1234	117	17	saturation	saturation	NOUN
cuesj-1234	117	18	of	of	ADP
cuesj-1234	117	19	the	the	DET
cuesj-1234	117	20	solution	solution	NOUN
cuesj-1234	117	21	preventing	prevent	VERB
cuesj-1234	117	22	further	further	ADJ
cuesj-1234	117	23	solubility	solubility	NOUN
cuesj-1234	117	24	.	.	PUNCT
cuesj-1234	118	1	theoretically	theoretically	ADV
cuesj-1234	118	2	,	,	PUNCT
cuesj-1234	118	3	the	the	DET
cuesj-1234	118	4	formation	formation	NOUN
cuesj-1234	118	5	of	of	ADP
cuesj-1234	118	6	sodium	sodium	NOUN
cuesj-1234	118	7	docusate	docusate	NOUN
cuesj-1234	118	8	micelles	micelle	NOUN
cuesj-1234	118	9	may	may	AUX
cuesj-1234	118	10	be	be	AUX
cuesj-1234	118	11	hindered	hinder	VERB
cuesj-1234	118	12	at	at	ADP
cuesj-1234	118	13	specific	specific	ADJ
cuesj-1234	118	14	concentrations	concentration	NOUN
cuesj-1234	118	15	of	of	ADP
cuesj-1234	118	16	isoleucine	isoleucine	NOUN
cuesj-1234	118	17	,	,	PUNCT
cuesj-1234	118	18	which	which	PRON
cuesj-1234	118	19	would	would	AUX
cuesj-1234	118	20	require	require	VERB
cuesj-1234	118	21	more	more	ADJ
cuesj-1234	118	22	refinements	refinement	NOUN
cuesj-1234	118	23	to	to	PART
cuesj-1234	118	24	determine	determine	VERB
cuesj-1234	118	25	for	for	ADP
cuesj-1234	118	26	certain	certain	ADJ
cuesj-1234	118	27	.	.	PUNCT
cuesj-1234	119	1	a	a	DET
cuesj-1234	119	2	possible	possible	ADJ
cuesj-1234	119	3	mechanism	mechanism	NOUN
cuesj-1234	119	4	may	may	AUX
cuesj-1234	119	5	involve	involve	VERB
cuesj-1234	119	6	the	the	DET
cuesj-1234	119	7	interaction	interaction	NOUN
cuesj-1234	119	8	between	between	ADP
cuesj-1234	119	9	the	the	DET
cuesj-1234	119	10	anionic	anionic	ADJ
cuesj-1234	119	11	,	,	PUNCT
cuesj-1234	119	12	i.e.	i.e.	X
cuesj-1234	119	13	,	,	PUNCT
cuesj-1234	119	14	the	the	DET
cuesj-1234	119	15	negative	negative	ADJ
cuesj-1234	119	16	part	part	NOUN
cuesj-1234	119	17	of	of	ADP
cuesj-1234	119	18	sodium	sodium	NOUN
cuesj-1234	119	19	docusate	docusate	NOUN
cuesj-1234	119	20	,	,	PUNCT
cuesj-1234	119	21	and	and	CCONJ
cuesj-1234	119	22	the	the	DET
cuesj-1234	119	23	potentially	potentially	ADV
cuesj-1234	119	24	positive	positive	ADJ
cuesj-1234	119	25	amine	amine	ADJ
cuesj-1234	119	26	group	group	NOUN
cuesj-1234	119	27	in	in	ADP
cuesj-1234	119	28	isoleucine	isoleucine	NOUN
cuesj-1234	119	29	,	,	PUNCT
cuesj-1234	119	30	or	or	CCONJ
cuesj-1234	119	31	amino	amino	ADJ
cuesj-1234	119	32	acids	acid	NOUN
cuesj-1234	119	33	in	in	ADP
cuesj-1234	119	34	general	general	ADJ
cuesj-1234	119	35	.	.	PUNCT
cuesj-1234	120	1	if	if	SCONJ
cuesj-1234	120	2	this	this	PRON
cuesj-1234	120	3	is	be	AUX
cuesj-1234	120	4	the	the	DET
cuesj-1234	120	5	case	case	NOUN
cuesj-1234	120	6	,	,	PUNCT
cuesj-1234	120	7	substituting	substitute	VERB
cuesj-1234	120	8	an	an	DET
cuesj-1234	120	9	amino	amino	NOUN
cuesj-1234	120	10	acid	acid	NOUN
cuesj-1234	120	11	with	with	ADP
cuesj-1234	120	12	an	an	DET
cuesj-1234	120	13	exposed	expose	VERB
cuesj-1234	120	14	positive	positive	ADJ
cuesj-1234	120	15	group	group	NOUN
cuesj-1234	120	16	,	,	PUNCT
cuesj-1234	120	17	such	such	ADJ
cuesj-1234	120	18	as	as	ADP
cuesj-1234	120	19	lysine	lysine	NOUN
cuesj-1234	120	20	,	,	PUNCT
cuesj-1234	120	21	arginine	arginine	NOUN
cuesj-1234	120	22	,	,	PUNCT
cuesj-1234	120	23	or	or	CCONJ
cuesj-1234	120	24	histidine	histidine	NOUN
cuesj-1234	120	25	,	,	PUNCT
cuesj-1234	120	26	may	may	AUX
cuesj-1234	120	27	yield	yield	VERB
cuesj-1234	120	28	even	even	ADV
cuesj-1234	120	29	more	more	ADV
cuesj-1234	120	30	positive	positive	ADJ
cuesj-1234	120	31	results	result	NOUN
cuesj-1234	120	32	.	.	PUNCT
cuesj-1234	121	1	this	this	PRON
cuesj-1234	121	2	is	be	AUX
cuesj-1234	121	3	supported	support	VERB
cuesj-1234	121	4	by	by	ADP
cuesj-1234	121	5	the	the	DET
cuesj-1234	121	6	fact	fact	NOUN
cuesj-1234	121	7	that	that	SCONJ
cuesj-1234	121	8	adding	add	VERB
cuesj-1234	121	9	arginine	arginine	NOUN
cuesj-1234	121	10	into	into	ADP
cuesj-1234	121	11	the	the	DET
cuesj-1234	121	12	solution	solution	NOUN
cuesj-1234	121	13	resulted	result	VERB
cuesj-1234	121	14	in	in	ADP
cuesj-1234	121	15	a	a	DET
cuesj-1234	121	16	huge	huge	ADJ
cuesj-1234	121	17	improvement	improvement	NOUN
cuesj-1234	121	18	in	in	ADP
cuesj-1234	121	19	the	the	DET
cuesj-1234	121	20	solubility	solubility	NOUN
cuesj-1234	121	21	of	of	ADP
cuesj-1234	121	22	simvastatin.[24	simvastatin.[24	PROPN
cuesj-1234	121	23	]	]	PUNCT
cuesj-1234	121	24	isoleucine	isoleucine	NOUN
cuesj-1234	121	25	may	may	AUX
cuesj-1234	121	26	also	also	ADV
cuesj-1234	121	27	have	have	AUX
cuesj-1234	121	28	formed	form	VERB
cuesj-1234	121	29	a	a	DET
cuesj-1234	121	30	complex	complex	NOUN
cuesj-1234	121	31	with	with	ADP
cuesj-1234	121	32	the	the	DET
cuesj-1234	121	33	simvastatin	simvastatin	NOUN
cuesj-1234	121	34	,	,	PUNCT
cuesj-1234	121	35	making	make	VERB
cuesj-1234	121	36	it	it	PRON
cuesj-1234	121	37	more	more	ADV
cuesj-1234	121	38	polar	polar	ADJ
cuesj-1234	121	39	and	and	CCONJ
cuesj-1234	121	40	soluble	soluble	ADJ
cuesj-1234	121	41	,	,	PUNCT
cuesj-1234	121	42	as	as	ADP
cuesj-1234	121	43	in	in	ADP
cuesj-1234	121	44	the	the	DET
cuesj-1234	121	45	experiment	experiment	NOUN
cuesj-1234	121	46	with	with	ADP
cuesj-1234	121	47	arginine	arginine	NOUN
cuesj-1234	121	48	.	.	PUNCT
cuesj-1234	122	1	arginine	arginine	PROPN
cuesj-1234	122	2	has	have	VERB
cuesj-1234	122	3	multiple	multiple	ADJ
cuesj-1234	122	4	nh	nh	NOUN
cuesj-1234	122	5	groups	group	NOUN
cuesj-1234	122	6	,	,	PUNCT
cuesj-1234	122	7	while	while	SCONJ
cuesj-1234	122	8	isoleucine	isoleucine	NOUN
cuesj-1234	122	9	only	only	ADV
cuesj-1234	122	10	has	have	VERB
cuesj-1234	122	11	one	one	NUM
cuesj-1234	122	12	,	,	PUNCT
cuesj-1234	122	13	and	and	CCONJ
cuesj-1234	122	14	that	that	PRON
cuesj-1234	122	15	may	may	AUX
cuesj-1234	122	16	contribute	contribute	VERB
cuesj-1234	122	17	to	to	ADP
cuesj-1234	122	18	its	its	PRON
cuesj-1234	122	19	greater	great	ADJ
cuesj-1234	122	20	effectiveness	effectiveness	NOUN
cuesj-1234	122	21	.	.	PUNCT
cuesj-1234	123	1	on	on	ADP
cuesj-1234	123	2	the	the	DET
cuesj-1234	123	3	other	other	ADJ
cuesj-1234	123	4	hand	hand	NOUN
cuesj-1234	123	5	,	,	PUNCT
cuesj-1234	123	6	a	a	DET
cuesj-1234	123	7	more	more	ADV
cuesj-1234	123	8	negatively	negatively	ADV
cuesj-1234	123	9	charged	charge	VERB
cuesj-1234	123	10	amino	amino	NOUN
cuesj-1234	123	11	acid	acid	NOUN
cuesj-1234	123	12	may	may	AUX
cuesj-1234	123	13	decrease	decrease	VERB
cuesj-1234	123	14	the	the	DET
cuesj-1234	123	15	effectiveness	effectiveness	NOUN
cuesj-1234	123	16	of	of	ADP
cuesj-1234	123	17	the	the	DET
cuesj-1234	123	18	excipients	excipient	NOUN
cuesj-1234	123	19	’	'	PUNCT
cuesj-1234	123	20	actions	action	NOUN
cuesj-1234	123	21	alone	alone	ADJ
cuesj-1234	123	22	or	or	CCONJ
cuesj-1234	123	23	together	together	ADV
cuesj-1234	123	24	.	.	PUNCT
cuesj-1234	124	1	in	in	ADP
cuesj-1234	124	2	the	the	DET
cuesj-1234	124	3	dissolution	dissolution	NOUN
cuesj-1234	124	4	process	process	NOUN
cuesj-1234	124	5	for	for	ADP
cuesj-1234	124	6	each	each	DET
cuesj-1234	124	7	ratio	ratio	NOUN
cuesj-1234	124	8	,	,	PUNCT
cuesj-1234	124	9	the	the	DET
cuesj-1234	124	10	time	time	NOUN
cuesj-1234	124	11	required	require	VERB
cuesj-1234	124	12	until	until	ADP
cuesj-1234	124	13	complete	complete	ADJ
cuesj-1234	124	14	saturation	saturation	NOUN
cuesj-1234	124	15	varied	varied	ADJ
cuesj-1234	124	16	.	.	PUNCT
cuesj-1234	125	1	the	the	DET
cuesj-1234	125	2	lowest	low	ADJ
cuesj-1234	125	3	excipient	excipient	ADJ
cuesj-1234	125	4	concentration	concentration	NOUN
cuesj-1234	125	5	of	of	ADP
cuesj-1234	125	6	4:1	4:1	NUM
cuesj-1234	125	7	simvastatin	simvastatin	NOUN
cuesj-1234	125	8	:	:	PUNCT
cuesj-1234	125	9	excipients	excipient	NOUN
cuesj-1234	125	10	required	require	VERB
cuesj-1234	125	11	only	only	ADV
cuesj-1234	125	12	about	about	ADV
cuesj-1234	125	13	15	15	NUM
cuesj-1234	125	14	min	min	NOUN
cuesj-1234	125	15	on	on	ADP
cuesj-1234	125	16	the	the	DET
cuesj-1234	125	17	magnetic	magnetic	ADJ
cuesj-1234	125	18	stirrer	stirrer	NOUN
cuesj-1234	125	19	due	due	ADP
cuesj-1234	125	20	to	to	ADP
cuesj-1234	125	21	the	the	DET
cuesj-1234	125	22	relatively	relatively	ADV
cuesj-1234	125	23	low	low	ADJ
cuesj-1234	125	24	solubility	solubility	NOUN
cuesj-1234	125	25	of	of	ADP
cuesj-1234	125	26	the	the	DET
cuesj-1234	125	27	product	product	NOUN
cuesj-1234	125	28	.	.	PUNCT
cuesj-1234	126	1	the	the	DET
cuesj-1234	126	2	middle	middle	ADJ
cuesj-1234	126	3	sample	sample	NOUN
cuesj-1234	126	4	,	,	PUNCT
cuesj-1234	126	5	with	with	ADP
cuesj-1234	126	6	a	a	DET
cuesj-1234	126	7	2:1	2:1	NUM
cuesj-1234	126	8	ratio	ratio	NOUN
cuesj-1234	126	9	,	,	PUNCT
cuesj-1234	126	10	took	take	VERB
cuesj-1234	126	11	much	much	ADV
cuesj-1234	126	12	longer	long	ADV
cuesj-1234	126	13	,	,	PUNCT
cuesj-1234	126	14	at	at	ADP
cuesj-1234	126	15	about	about	ADV
cuesj-1234	126	16	45	45	NUM
cuesj-1234	126	17	min	min	NOUN
cuesj-1234	126	18	.	.	PUNCT
cuesj-1234	127	1	the	the	DET
cuesj-1234	127	2	final	final	ADJ
cuesj-1234	127	3	ratio	ratio	NOUN
cuesj-1234	127	4	of	of	ADP
cuesj-1234	127	5	4:3	4:3	NUM
cuesj-1234	127	6	took	take	VERB
cuesj-1234	127	7	1.5	1.5	NUM
cuesj-1234	127	8	h	h	NOUN
cuesj-1234	127	9	to	to	PART
cuesj-1234	127	10	solubilize	solubilize	VERB
cuesj-1234	127	11	and	and	CCONJ
cuesj-1234	127	12	become	become	VERB
cuesj-1234	127	13	saturated	saturate	VERB
cuesj-1234	127	14	,	,	PUNCT
cuesj-1234	127	15	even	even	ADV
cuesj-1234	127	16	though	though	SCONJ
cuesj-1234	127	17	ultimately	ultimately	ADV
cuesj-1234	127	18	,	,	PUNCT
cuesj-1234	127	19	it	it	PRON
cuesj-1234	127	20	had	have	VERB
cuesj-1234	127	21	a	a	DET
cuesj-1234	127	22	lower	low	ADJ
cuesj-1234	127	23	simvastatin	simvastatin	ADJ
cuesj-1234	127	24	concentration	concentration	NOUN
cuesj-1234	127	25	in	in	ADP
cuesj-1234	127	26	the	the	DET
cuesj-1234	127	27	solution	solution	NOUN
cuesj-1234	127	28	.	.	PUNCT
cuesj-1234	128	1	this	this	PRON
cuesj-1234	128	2	may	may	AUX
cuesj-1234	128	3	be	be	AUX
cuesj-1234	128	4	due	due	ADJ
cuesj-1234	128	5	to	to	ADP
cuesj-1234	128	6	the	the	DET
cuesj-1234	128	7	drying	dry	VERB
cuesj-1234	128	8	out	out	ADP
cuesj-1234	128	9	of	of	ADP
cuesj-1234	128	10	the	the	DET
cuesj-1234	128	11	excipients	excipient	NOUN
cuesj-1234	128	12	to	to	PART
cuesj-1234	128	13	form	form	VERB
cuesj-1234	128	14	a	a	DET
cuesj-1234	128	15	physical	physical	ADJ
cuesj-1234	128	16	coating	coating	NOUN
cuesj-1234	128	17	,	,	PUNCT
cuesj-1234	128	18	similar	similar	ADJ
cuesj-1234	128	19	to	to	ADP
cuesj-1234	128	20	a	a	DET
cuesj-1234	128	21	hard	hard	ADJ
cuesj-1234	128	22	shell	shell	NOUN
cuesj-1234	128	23	,	,	PUNCT
cuesj-1234	128	24	that	that	PRON
cuesj-1234	128	25	did	do	AUX
cuesj-1234	128	26	not	not	PART
cuesj-1234	128	27	allow	allow	VERB
cuesj-1234	128	28	water	water	NOUN
cuesj-1234	128	29	to	to	PART
cuesj-1234	128	30	penetrate	penetrate	VERB
cuesj-1234	128	31	past	past	ADP
cuesj-1234	128	32	it	it	PRON
cuesj-1234	128	33	.	.	PUNCT
cuesj-1234	129	1	another	another	DET
cuesj-1234	129	2	possibility	possibility	NOUN
cuesj-1234	129	3	is	be	AUX
cuesj-1234	129	4	that	that	SCONJ
cuesj-1234	129	5	micelle	micelle	NOUN
cuesj-1234	129	6	formation	formation	NOUN
cuesj-1234	129	7	was	be	AUX
cuesj-1234	129	8	not	not	PART
cuesj-1234	129	9	completely	completely	ADV
cuesj-1234	129	10	successful	successful	ADJ
cuesj-1234	129	11	and	and	CCONJ
cuesj-1234	129	12	resulted	result	VERB
cuesj-1234	129	13	in	in	ADP
cuesj-1234	129	14	incomplete	incomplete	ADJ
cuesj-1234	129	15	solubilization	solubilization	NOUN
cuesj-1234	129	16	for	for	ADP
cuesj-1234	129	17	some	some	PRON
cuesj-1234	129	18	of	of	ADP
cuesj-1234	129	19	the	the	DET
cuesj-1234	129	20	particles	particle	NOUN
cuesj-1234	129	21	,	,	PUNCT
cuesj-1234	129	22	as	as	ADP
cuesj-1234	129	23	a	a	DET
cuesj-1234	129	24	result	result	NOUN
cuesj-1234	129	25	of	of	ADP
cuesj-1234	129	26	excess	excess	ADJ
cuesj-1234	129	27	saturation	saturation	NOUN
cuesj-1234	129	28	,	,	PUNCT
cuesj-1234	129	29	interaction	interaction	NOUN
cuesj-1234	129	30	with	with	ADP
cuesj-1234	129	31	isoleucine	isoleucine	NOUN
cuesj-1234	129	32	or	or	CCONJ
cuesj-1234	129	33	simvastatin	simvastatin	NOUN
cuesj-1234	129	34	,	,	PUNCT
cuesj-1234	129	35	or	or	CCONJ
cuesj-1234	129	36	another	another	DET
cuesj-1234	129	37	unknown	unknown	ADJ
cuesj-1234	129	38	mechanism.[34	mechanism.[34	NOUN
cuesj-1234	129	39	]	]	PUNCT
cuesj-1234	129	40	although	although	SCONJ
cuesj-1234	129	41	some	some	DET
cuesj-1234	129	42	positive	positive	ADJ
cuesj-1234	129	43	results	result	NOUN
cuesj-1234	129	44	were	be	AUX
cuesj-1234	129	45	found	find	VERB
cuesj-1234	129	46	,	,	PUNCT
cuesj-1234	129	47	there	there	PRON
cuesj-1234	129	48	were	be	VERB
cuesj-1234	129	49	many	many	ADJ
cuesj-1234	129	50	combinations	combination	NOUN
cuesj-1234	129	51	and	and	CCONJ
cuesj-1234	129	52	ratios	ratio	NOUN
cuesj-1234	129	53	that	that	PRON
cuesj-1234	129	54	did	do	AUX
cuesj-1234	129	55	not	not	PART
cuesj-1234	129	56	yield	yield	VERB
cuesj-1234	129	57	satisfactory	satisfactory	ADJ
cuesj-1234	129	58	solid	solid	ADJ
cuesj-1234	129	59	dispersions	dispersion	NOUN
cuesj-1234	129	60	,	,	PUNCT
cuesj-1234	129	61	and	and	CCONJ
cuesj-1234	129	62	these	these	PRON
cuesj-1234	129	63	occurred	occur	VERB
cuesj-1234	129	64	when	when	SCONJ
cuesj-1234	129	65	too	too	ADV
cuesj-1234	129	66	much	much	ADJ
cuesj-1234	129	67	isoleucine	isoleucine	NOUN
cuesj-1234	129	68	or	or	CCONJ
cuesj-1234	129	69	docusate	docusate	NOUN
cuesj-1234	129	70	was	be	AUX
cuesj-1234	129	71	added	add	VERB
cuesj-1234	129	72	.	.	PUNCT
cuesj-1234	130	1	when	when	SCONJ
cuesj-1234	130	2	large	large	ADJ
cuesj-1234	130	3	amounts	amount	NOUN
cuesj-1234	130	4	of	of	ADP
cuesj-1234	130	5	docusate	docusate	NOUN
cuesj-1234	130	6	were	be	AUX
cuesj-1234	130	7	incorporated	incorporate	VERB
cuesj-1234	130	8	into	into	ADP
cuesj-1234	130	9	the	the	DET
cuesj-1234	130	10	mixture	mixture	NOUN
cuesj-1234	130	11	,	,	PUNCT
cuesj-1234	130	12	the	the	DET
cuesj-1234	130	13	product	product	NOUN
cuesj-1234	130	14	did	do	AUX
cuesj-1234	130	15	not	not	PART
cuesj-1234	130	16	dry	dry	VERB
cuesj-1234	130	17	correctly	correctly	ADV
cuesj-1234	130	18	and	and	CCONJ
cuesj-1234	130	19	stayed	stay	VERB
cuesj-1234	130	20	as	as	ADP
cuesj-1234	130	21	a	a	DET
cuesj-1234	130	22	jelly	jelly	NOUN
cuesj-1234	130	23	-	-	PUNCT
cuesj-1234	130	24	like	like	ADJ
cuesj-1234	130	25	semisolid	semisolid	NOUN
cuesj-1234	130	26	.	.	PUNCT
cuesj-1234	131	1	this	this	PRON
cuesj-1234	131	2	made	make	VERB
cuesj-1234	131	3	it	it	PRON
cuesj-1234	131	4	impossible	impossible	ADJ
cuesj-1234	131	5	to	to	PART
cuesj-1234	131	6	grind	grind	VERB
cuesj-1234	131	7	into	into	ADP
cuesj-1234	131	8	a	a	DET
cuesj-1234	131	9	powder	powder	NOUN
cuesj-1234	131	10	and	and	CCONJ
cuesj-1234	131	11	to	to	PART
cuesj-1234	131	12	dissolve	dissolve	VERB
cuesj-1234	131	13	into	into	ADP
cuesj-1234	131	14	water	water	NOUN
cuesj-1234	131	15	easily	easily	ADV
cuesj-1234	131	16	.	.	PUNCT
cuesj-1234	132	1	a	a	DET
cuesj-1234	132	2	viscous	viscous	ADJ
cuesj-1234	132	3	liquid	liquid	NOUN
cuesj-1234	132	4	that	that	PRON
cuesj-1234	132	5	did	do	AUX
cuesj-1234	132	6	not	not	PART
cuesj-1234	132	7	pass	pass	VERB
cuesj-1234	132	8	through	through	ADP
cuesj-1234	132	9	the	the	DET
cuesj-1234	132	10	filter	filter	NOUN
cuesj-1234	132	11	paper	paper	NOUN
cuesj-1234	132	12	was	be	AUX
cuesj-1234	132	13	the	the	DET
cuesj-1234	132	14	result	result	NOUN
cuesj-1234	132	15	of	of	ADP
cuesj-1234	132	16	attempting	attempt	VERB
cuesj-1234	132	17	to	to	PART
cuesj-1234	132	18	solubilize	solubilize	VERB
cuesj-1234	132	19	it	it	PRON
cuesj-1234	132	20	.	.	PUNCT
cuesj-1234	133	1	with	with	ADP
cuesj-1234	133	2	excess	excess	ADJ
cuesj-1234	133	3	isoleucine	isoleucine	NOUN
cuesj-1234	133	4	added	add	VERB
cuesj-1234	133	5	to	to	ADP
cuesj-1234	133	6	the	the	DET
cuesj-1234	133	7	mixture	mixture	NOUN
cuesj-1234	133	8	,	,	PUNCT
cuesj-1234	133	9	the	the	DET
cuesj-1234	133	10	product	product	NOUN
cuesj-1234	133	11	did	do	AUX
cuesj-1234	133	12	not	not	PART
cuesj-1234	133	13	dry	dry	VERB
cuesj-1234	133	14	into	into	ADP
cuesj-1234	133	15	a	a	DET
cuesj-1234	133	16	powder	powder	NOUN
cuesj-1234	133	17	,	,	PUNCT
cuesj-1234	133	18	and	and	CCONJ
cuesj-1234	133	19	there	there	PRON
cuesj-1234	133	20	was	be	VERB
cuesj-1234	133	21	a	a	DET
cuesj-1234	133	22	distinct	distinct	ADJ
cuesj-1234	133	23	separation	separation	NOUN
cuesj-1234	133	24	between	between	ADP
cuesj-1234	133	25	the	the	DET
cuesj-1234	133	26	two	two	NUM
cuesj-1234	133	27	layers	layer	NOUN
cuesj-1234	133	28	of	of	ADP
cuesj-1234	133	29	the	the	DET
cuesj-1234	133	30	solution	solution	NOUN
cuesj-1234	133	31	,	,	PUNCT
cuesj-1234	133	32	with	with	ADP
cuesj-1234	133	33	a	a	DET
cuesj-1234	133	34	turbid	turbid	ADJ
cuesj-1234	133	35	supernatant	supernatant	NOUN
cuesj-1234	133	36	on	on	ADP
cuesj-1234	133	37	top	top	NOUN
cuesj-1234	133	38	and	and	CCONJ
cuesj-1234	133	39	a	a	DET
cuesj-1234	133	40	thick	thick	ADJ
cuesj-1234	133	41	yellowish	yellowish	NOUN
cuesj-1234	133	42	layer	layer	NOUN
cuesj-1234	133	43	on	on	ADP
cuesj-1234	133	44	the	the	DET
cuesj-1234	133	45	bottom	bottom	NOUN
cuesj-1234	133	46	.	.	PUNCT
cuesj-1234	134	1	in	in	ADP
cuesj-1234	134	2	solutions	solution	NOUN
cuesj-1234	134	3	that	that	PRON
cuesj-1234	134	4	had	have	VERB
cuesj-1234	134	5	a	a	DET
cuesj-1234	134	6	1:3	1:3	NUM
cuesj-1234	134	7	ratio	ratio	NOUN
cuesj-1234	134	8	of	of	ADP
cuesj-1234	134	9	isoleucine	isoleucine	NOUN
cuesj-1234	134	10	in	in	ADP
cuesj-1234	134	11	a	a	DET
cuesj-1234	134	12	1	1	NUM
cuesj-1234	134	13	g	g	NOUN
cuesj-1234	134	14	:	:	PUNCT
cuesj-1234	134	15	3	3	NUM
cuesj-1234	134	16	g	g	NOUN
cuesj-1234	134	17	mix	mix	NOUN
cuesj-1234	134	18	,	,	PUNCT
cuesj-1234	134	19	there	there	PRON
cuesj-1234	134	20	was	be	VERB
cuesj-1234	134	21	adequate	adequate	ADJ
cuesj-1234	134	22	drying	dry	VERB
cuesj-1234	134	23	of	of	ADP
cuesj-1234	134	24	the	the	DET
cuesj-1234	134	25	solution	solution	NOUN
cuesj-1234	134	26	into	into	ADP
cuesj-1234	134	27	a	a	DET
cuesj-1234	134	28	solid	solid	ADJ
cuesj-1234	134	29	,	,	PUNCT
cuesj-1234	134	30	but	but	CCONJ
cuesj-1234	134	31	there	there	PRON
cuesj-1234	134	32	was	be	VERB
cuesj-1234	134	33	an	an	DET
cuesj-1234	134	34	inhomogeneous	inhomogeneous	ADJ
cuesj-1234	134	35	product	product	NOUN
cuesj-1234	134	36	obtained	obtain	VERB
cuesj-1234	134	37	,	,	PUNCT
cuesj-1234	134	38	which	which	PRON
cuesj-1234	134	39	meant	mean	VERB
cuesj-1234	134	40	the	the	DET
cuesj-1234	134	41	isoleucine	isoleucine	NOUN
cuesj-1234	134	42	was	be	AUX
cuesj-1234	134	43	unevenly	unevenly	ADV
cuesj-1234	134	44	distributed	distribute	VERB
cuesj-1234	134	45	.	.	PUNCT
cuesj-1234	135	1	this	this	PRON
cuesj-1234	135	2	could	could	AUX
cuesj-1234	135	3	be	be	AUX
cuesj-1234	135	4	due	due	ADJ
cuesj-1234	135	5	to	to	ADP
cuesj-1234	135	6	precipitation,[35	precipitation,[35	NUM
cuesj-1234	135	7	]	]	PUNCT
cuesj-1234	135	8	or	or	CCONJ
cuesj-1234	135	9	uneven	uneven	ADJ
cuesj-1234	135	10	solvation	solvation	NOUN
cuesj-1234	135	11	and	and	CCONJ
cuesj-1234	135	12	solid	solid	ADJ
cuesj-1234	135	13	dispersion	dispersion	NOUN
cuesj-1234	135	14	formation	formation	NOUN
cuesj-1234	135	15	due	due	ADP
cuesj-1234	135	16	to	to	ADP
cuesj-1234	135	17	high	high	ADJ
cuesj-1234	135	18	solution	solution	NOUN
cuesj-1234	135	19	saturation	saturation	NOUN
cuesj-1234	135	20	.	.	PUNCT
cuesj-1234	136	1	the	the	DET
cuesj-1234	136	2	percentage	percentage	NOUN
cuesj-1234	136	3	of	of	ADP
cuesj-1234	136	4	isoleucine	isoleucine	NOUN
cuesj-1234	136	5	in	in	ADP
cuesj-1234	136	6	the	the	DET
cuesj-1234	136	7	solution	solution	NOUN
cuesj-1234	136	8	should	should	AUX
cuesj-1234	136	9	not	not	PART
cuesj-1234	136	10	be	be	AUX
cuesj-1234	136	11	dramatically	dramatically	ADV
cuesj-1234	136	12	more	more	ADJ
cuesj-1234	136	13	than	than	ADP
cuesj-1234	136	14	simvastatin	simvastatin	NOUN
cuesj-1234	136	15	to	to	PART
cuesj-1234	136	16	have	have	VERB
cuesj-1234	136	17	a	a	DET
cuesj-1234	136	18	stable	stable	ADJ
cuesj-1234	136	19	solid	solid	ADJ
cuesj-1234	136	20	dispersion	dispersion	NOUN
cuesj-1234	136	21	.	.	PUNCT
cuesj-1234	137	1	figure	figure	VERB
cuesj-1234	137	2	6	6	NUM
cuesj-1234	137	3	:	:	PUNCT
cuesj-1234	137	4	starting	start	VERB
cuesj-1234	137	5	materials	material	NOUN
cuesj-1234	137	6	figure	figure	VERB
cuesj-1234	137	7	7	7	NUM
cuesj-1234	137	8	:	:	PUNCT
cuesj-1234	137	9	simvastatin	simvastatin	PROPN
cuesj-1234	137	10	calibration	calibration	NOUN
cuesj-1234	137	11	curve	curve	NOUN
cuesj-1234	137	12	al	al	PROPN
cuesj-1234	137	13	-	-	PUNCT
cuesj-1234	137	14	jumaili	jumaili	PROPN
cuesj-1234	137	15	,	,	PUNCT
cuesj-1234	137	16	et	et	PROPN
cuesj-1234	137	17	al	al	PROPN
cuesj-1234	137	18	.	.	PROPN
cuesj-1234	137	19	:	:	PUNCT
cuesj-1234	138	1	enhancing	enhance	VERB
cuesj-1234	138	2	solubility	solubility	NOUN
cuesj-1234	138	3	of	of	ADP
cuesj-1234	138	4	simvastatin	simvastatin	NOUN
cuesj-1234	138	5	with	with	ADP
cuesj-1234	138	6	l	l	NOUN
cuesj-1234	138	7	-	-	NOUN
cuesj-1234	138	8	isoleucine	isoleucine	ADJ
cuesj-1234	138	9	and	and	CCONJ
cuesj-1234	138	10	sodium	sodium	NOUN
cuesj-1234	138	11	docusate	docusate	NOUN
cuesj-1234	138	12	31	31	NUM
cuesj-1234	138	13	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	138	14	cuesj	cuesj	NOUN
cuesj-1234	138	15	2025	2025	NUM
cuesj-1234	138	16	,	,	PUNCT
cuesj-1234	138	17	9	9	NUM
cuesj-1234	138	18	(	(	PUNCT
cuesj-1234	138	19	2	2	NUM
cuesj-1234	138	20	):	):	PUNCT
cuesj-1234	138	21	26	26	NUM
cuesj-1234	138	22	-	-	SYM
cuesj-1234	138	23	32	32	NUM
cuesj-1234	138	24	the	the	DET
cuesj-1234	138	25	final	final	ADJ
cuesj-1234	138	26	concentration	concentration	NOUN
cuesj-1234	138	27	of	of	ADP
cuesj-1234	138	28	the	the	DET
cuesj-1234	138	29	modified	modify	VERB
cuesj-1234	138	30	simvastatin	simvastatin	NOUN
cuesj-1234	138	31	in	in	ADP
cuesj-1234	138	32	water	water	NOUN
cuesj-1234	138	33	is	be	AUX
cuesj-1234	138	34	not	not	PART
cuesj-1234	138	35	enough	enough	ADJ
cuesj-1234	138	36	to	to	PART
cuesj-1234	138	37	change	change	VERB
cuesj-1234	138	38	its	its	PRON
cuesj-1234	138	39	classification	classification	NOUN
cuesj-1234	138	40	from	from	ADP
cuesj-1234	138	41	being	be	AUX
cuesj-1234	138	42	insoluble	insoluble	ADJ
cuesj-1234	138	43	to	to	ADP
cuesj-1234	138	44	soluble	soluble	ADJ
cuesj-1234	138	45	,	,	PUNCT
cuesj-1234	138	46	though	though	SCONJ
cuesj-1234	138	47	it	it	PRON
cuesj-1234	138	48	is	be	AUX
cuesj-1234	138	49	certainly	certainly	ADV
cuesj-1234	138	50	a	a	DET
cuesj-1234	138	51	step	step	NOUN
cuesj-1234	138	52	in	in	ADP
cuesj-1234	138	53	the	the	DET
cuesj-1234	138	54	right	right	ADJ
cuesj-1234	138	55	direction	direction	NOUN
cuesj-1234	138	56	.	.	PUNCT
cuesj-1234	139	1	as	as	SCONJ
cuesj-1234	139	2	previously	previously	ADV
cuesj-1234	139	3	mentioned	mention	VERB
cuesj-1234	139	4	,	,	PUNCT
cuesj-1234	139	5	in	in	ADP
cuesj-1234	139	6	order	order	NOUN
cuesj-1234	139	7	to	to	PART
cuesj-1234	139	8	be	be	AUX
cuesj-1234	139	9	classified	classify	VERB
cuesj-1234	139	10	as	as	ADP
cuesj-1234	139	11	soluble	soluble	ADJ
cuesj-1234	139	12	,	,	PUNCT
cuesj-1234	139	13	a	a	DET
cuesj-1234	139	14	drug	drug	NOUN
cuesj-1234	139	15	must	must	AUX
cuesj-1234	139	16	have	have	VERB
cuesj-1234	139	17	a	a	DET
cuesj-1234	139	18	solubility	solubility	NOUN
cuesj-1234	139	19	of	of	ADP
cuesj-1234	139	20	33	33	NUM
cuesj-1234	139	21	mg	mg	NOUN
cuesj-1234	139	22	/	/	SYM
cuesj-1234	139	23	ml	ml	NOUN
cuesj-1234	139	24	or	or	CCONJ
cuesj-1234	139	25	more	more	ADJ
cuesj-1234	139	26	,	,	PUNCT
cuesj-1234	139	27	according	accord	VERB
cuesj-1234	139	28	to	to	ADP
cuesj-1234	139	29	the	the	DET
cuesj-1234	139	30	usp	usp	NOUN
cuesj-1234	139	31	.	.	PUNCT
cuesj-1234	140	1	the	the	DET
cuesj-1234	140	2	smallest	small	ADJ
cuesj-1234	140	3	improvement	improvement	NOUN
cuesj-1234	140	4	resulted	result	VERB
cuesj-1234	140	5	in	in	ADP
cuesj-1234	140	6	a	a	DET
cuesj-1234	140	7	solubility	solubility	NOUN
cuesj-1234	140	8	of	of	ADP
cuesj-1234	140	9	97.5	97.5	NUM
cuesj-1234	140	10	µg	µg	NOUN
cuesj-1234	140	11	/	/	SYM
cuesj-1234	140	12	ml	ml	NOUN
cuesj-1234	140	13	,	,	PUNCT
cuesj-1234	140	14	which	which	PRON
cuesj-1234	140	15	is	be	AUX
cuesj-1234	140	16	still	still	ADV
cuesj-1234	140	17	within	within	ADP
cuesj-1234	140	18	the	the	DET
cuesj-1234	140	19	“	"	PUNCT
cuesj-1234	140	20	insoluble	insoluble	ADJ
cuesj-1234	140	21	”	"	PUNCT
cuesj-1234	140	22	category	category	NOUN
cuesj-1234	140	23	.	.	PUNCT
cuesj-1234	141	1	the	the	DET
cuesj-1234	141	2	next	next	ADJ
cuesj-1234	141	3	higher	high	ADJ
cuesj-1234	141	4	solubility	solubility	NOUN
cuesj-1234	141	5	was	be	AUX
cuesj-1234	141	6	312.8	312.8	NUM
cuesj-1234	141	7	µg	µg	NOUN
cuesj-1234	141	8	/	/	SYM
cuesj-1234	141	9	ml	ml	NOUN
cuesj-1234	141	10	,	,	PUNCT
cuesj-1234	141	11	which	which	PRON
cuesj-1234	141	12	is	be	AUX
cuesj-1234	141	13	0.3	0.3	NUM
cuesj-1234	141	14	mg	mg	PROPN
cuesj-1234	141	15	/	/	SYM
cuesj-1234	141	16	ml	ml	NOUN
cuesj-1234	141	17	.	.	PUNCT
cuesj-1234	142	1	this	this	PRON
cuesj-1234	142	2	is	be	AUX
cuesj-1234	142	3	enough	enough	ADJ
cuesj-1234	142	4	to	to	PART
cuesj-1234	142	5	take	take	VERB
cuesj-1234	142	6	simvastatin	simvastatin	NOUN
cuesj-1234	142	7	out	out	ADP
cuesj-1234	142	8	of	of	ADP
cuesj-1234	142	9	the	the	DET
cuesj-1234	142	10	“	"	PUNCT
cuesj-1234	142	11	insoluble	insoluble	ADJ
cuesj-1234	142	12	”	"	PUNCT
cuesj-1234	142	13	category	category	NOUN
cuesj-1234	142	14	and	and	CCONJ
cuesj-1234	142	15	raise	raise	VERB
cuesj-1234	142	16	it	it	PRON
cuesj-1234	142	17	to	to	ADP
cuesj-1234	142	18	“	"	PUNCT
cuesj-1234	142	19	very	very	ADV
cuesj-1234	142	20	slightly	slightly	ADV
cuesj-1234	142	21	soluble	soluble	ADJ
cuesj-1234	142	22	”	"	PUNCT
cuesj-1234	142	23	category	category	NOUN
cuesj-1234	142	24	.	.	PUNCT
cuesj-1234	143	1	the	the	DET
cuesj-1234	143	2	greatest	great	ADJ
cuesj-1234	143	3	change	change	NOUN
cuesj-1234	143	4	was	be	AUX
cuesj-1234	143	5	467.5	467.5	NUM
cuesj-1234	143	6	µg	µg	NOUN
cuesj-1234	143	7	/	/	SYM
cuesj-1234	143	8	ml	ml	NOUN
cuesj-1234	143	9	,	,	PUNCT
cuesj-1234	143	10	which	which	PRON
cuesj-1234	143	11	is	be	AUX
cuesj-1234	143	12	approximately	approximately	ADV
cuesj-1234	143	13	0.5	0.5	NUM
cuesj-1234	143	14	mg	mg	NUM
cuesj-1234	143	15	/	/	SYM
cuesj-1234	143	16	ml	ml	NOUN
cuesj-1234	143	17	.	.	PUNCT
cuesj-1234	144	1	this	this	PRON
cuesj-1234	144	2	also	also	ADV
cuesj-1234	144	3	removes	remove	VERB
cuesj-1234	144	4	simvastatin	simvastatin	NOUN
cuesj-1234	144	5	out	out	ADP
cuesj-1234	144	6	of	of	ADP
cuesj-1234	144	7	“	"	PUNCT
cuesj-1234	144	8	insoluble	insoluble	ADJ
cuesj-1234	144	9	”	"	PUNCT
cuesj-1234	144	10	and	and	CCONJ
cuesj-1234	144	11	to	to	AUX
cuesj-1234	144	12	“	"	PUNCT
cuesj-1234	144	13	very	very	ADV
cuesj-1234	144	14	slightly	slightly	ADV
cuesj-1234	144	15	soluble	soluble	ADJ
cuesj-1234	144	16	.	.	PUNCT
cuesj-1234	144	17	”	"	PUNCT
cuesj-1234	145	1	though	though	SCONJ
cuesj-1234	145	2	these	these	DET
cuesj-1234	145	3	findings	finding	NOUN
cuesj-1234	145	4	are	be	AUX
cuesj-1234	145	5	modest	modest	ADJ
cuesj-1234	145	6	when	when	SCONJ
cuesj-1234	145	7	looked	look	VERB
cuesj-1234	145	8	at	at	ADP
cuesj-1234	145	9	in	in	ADP
cuesj-1234	145	10	the	the	DET
cuesj-1234	145	11	absolute	absolute	ADJ
cuesj-1234	145	12	,	,	PUNCT
cuesj-1234	145	13	they	they	PRON
cuesj-1234	145	14	represent	represent	VERB
cuesj-1234	145	15	an	an	DET
cuesj-1234	145	16	open	open	ADJ
cuesj-1234	145	17	pathway	pathway	NOUN
cuesj-1234	145	18	that	that	PRON
cuesj-1234	145	19	may	may	AUX
cuesj-1234	145	20	lead	lead	VERB
cuesj-1234	145	21	to	to	ADP
cuesj-1234	145	22	greater	great	ADJ
cuesj-1234	145	23	improvements	improvement	NOUN
cuesj-1234	145	24	if	if	SCONJ
cuesj-1234	145	25	certain	certain	ADJ
cuesj-1234	145	26	variables	variable	NOUN
cuesj-1234	145	27	and	and	CCONJ
cuesj-1234	145	28	parameters	parameter	NOUN
cuesj-1234	145	29	are	be	AUX
cuesj-1234	145	30	changed	change	VERB
cuesj-1234	145	31	.	.	PUNCT
cuesj-1234	146	1	for	for	ADP
cuesj-1234	146	2	example	example	NOUN
cuesj-1234	146	3	,	,	PUNCT
cuesj-1234	146	4	a	a	DET
cuesj-1234	146	5	change	change	NOUN
cuesj-1234	146	6	in	in	ADP
cuesj-1234	146	7	the	the	DET
cuesj-1234	146	8	amino	amino	NOUN
cuesj-1234	146	9	acid	acid	NOUN
cuesj-1234	146	10	used	use	VERB
cuesj-1234	146	11	may	may	AUX
cuesj-1234	146	12	yield	yield	VERB
cuesj-1234	146	13	different	different	ADJ
cuesj-1234	146	14	results	result	NOUN
cuesj-1234	146	15	.	.	PUNCT
cuesj-1234	147	1	a	a	DET
cuesj-1234	147	2	combination	combination	NOUN
cuesj-1234	147	3	of	of	ADP
cuesj-1234	147	4	amino	amino	ADJ
cuesj-1234	147	5	acids	acid	NOUN
cuesj-1234	147	6	with	with	ADP
cuesj-1234	147	7	another	another	DET
cuesj-1234	147	8	form	form	NOUN
cuesj-1234	147	9	of	of	ADP
cuesj-1234	147	10	surfactant	surfactant	NOUN
cuesj-1234	147	11	,	,	PUNCT
cuesj-1234	147	12	such	such	ADJ
cuesj-1234	147	13	as	as	ADP
cuesj-1234	147	14	certain	certain	ADJ
cuesj-1234	147	15	polymers	polymer	NOUN
cuesj-1234	147	16	,	,	PUNCT
cuesj-1234	147	17	may	may	AUX
cuesj-1234	147	18	allow	allow	VERB
cuesj-1234	147	19	for	for	ADP
cuesj-1234	147	20	greater	great	ADJ
cuesj-1234	147	21	solubility	solubility	NOUN
cuesj-1234	147	22	depending	depend	VERB
cuesj-1234	147	23	on	on	ADP
cuesj-1234	147	24	the	the	DET
cuesj-1234	147	25	strength	strength	NOUN
cuesj-1234	147	26	of	of	ADP
cuesj-1234	147	27	the	the	DET
cuesj-1234	147	28	surfactant	surfactant	NOUN
cuesj-1234	147	29	.	.	PUNCT
cuesj-1234	148	1	another	another	DET
cuesj-1234	148	2	form	form	NOUN
cuesj-1234	148	3	of	of	ADP
cuesj-1234	148	4	solvent	solvent	NOUN
cuesj-1234	148	5	may	may	AUX
cuesj-1234	148	6	be	be	AUX
cuesj-1234	148	7	used	use	VERB
cuesj-1234	148	8	in	in	ADP
cuesj-1234	148	9	place	place	NOUN
cuesj-1234	148	10	of	of	ADP
cuesj-1234	148	11	ethanol	ethanol	NOUN
cuesj-1234	148	12	,	,	PUNCT
cuesj-1234	148	13	such	such	ADJ
cuesj-1234	148	14	as	as	ADP
cuesj-1234	148	15	chloroform	chloroform	NOUN
cuesj-1234	148	16	or	or	CCONJ
cuesj-1234	148	17	acetone	acetone	NOUN
cuesj-1234	148	18	and	and	CCONJ
cuesj-1234	148	19	water	water	NOUN
cuesj-1234	148	20	,	,	PUNCT
cuesj-1234	148	21	which	which	PRON
cuesj-1234	148	22	may	may	AUX
cuesj-1234	148	23	affect	affect	VERB
cuesj-1234	148	24	the	the	DET
cuesj-1234	148	25	extent	extent	NOUN
cuesj-1234	148	26	of	of	ADP
cuesj-1234	148	27	homogeneity	homogeneity	NOUN
cuesj-1234	148	28	or	or	CCONJ
cuesj-1234	148	29	dissolution	dissolution	NOUN
cuesj-1234	148	30	,	,	PUNCT
cuesj-1234	148	31	and	and	CCONJ
cuesj-1234	148	32	thus	thus	ADV
cuesj-1234	148	33	affect	affect	VERB
cuesj-1234	148	34	the	the	DET
cuesj-1234	148	35	resulting	result	VERB
cuesj-1234	148	36	solid	solid	ADJ
cuesj-1234	148	37	dispersion	dispersion	NOUN
cuesj-1234	148	38	.	.	PUNCT
cuesj-1234	149	1	a	a	DET
cuesj-1234	149	2	study	study	NOUN
cuesj-1234	149	3	to	to	PART
cuesj-1234	149	4	determine	determine	VERB
cuesj-1234	149	5	the	the	DET
cuesj-1234	149	6	exact	exact	ADJ
cuesj-1234	149	7	drug	drug	NOUN
cuesj-1234	149	8	content	content	NOUN
cuesj-1234	149	9	of	of	ADP
cuesj-1234	149	10	the	the	DET
cuesj-1234	149	11	solid	solid	ADJ
cuesj-1234	149	12	dispersion	dispersion	NOUN
cuesj-1234	149	13	after	after	SCONJ
cuesj-1234	149	14	it	it	PRON
cuesj-1234	149	15	is	be	AUX
cuesj-1234	149	16	dissolved	dissolve	VERB
cuesj-1234	149	17	in	in	ADP
cuesj-1234	149	18	water	water	NOUN
cuesj-1234	149	19	may	may	AUX
cuesj-1234	149	20	be	be	AUX
cuesj-1234	149	21	helpful	helpful	ADJ
cuesj-1234	149	22	to	to	PART
cuesj-1234	149	23	understand	understand	VERB
cuesj-1234	149	24	how	how	SCONJ
cuesj-1234	149	25	much	much	ADJ
cuesj-1234	149	26	of	of	ADP
cuesj-1234	149	27	the	the	DET
cuesj-1234	149	28	solid	solid	ADJ
cuesj-1234	149	29	dispersion	dispersion	NOUN
cuesj-1234	149	30	is	be	AUX
cuesj-1234	149	31	truly	truly	ADV
cuesj-1234	149	32	effective	effective	ADJ
cuesj-1234	149	33	material	material	NOUN
cuesj-1234	149	34	.	.	PUNCT
cuesj-1234	150	1	it	it	PRON
cuesj-1234	150	2	will	will	AUX
cuesj-1234	150	3	also	also	ADV
cuesj-1234	150	4	give	give	VERB
cuesj-1234	150	5	a	a	DET
cuesj-1234	150	6	clue	clue	NOUN
cuesj-1234	150	7	about	about	ADP
cuesj-1234	150	8	what	what	PRON
cuesj-1234	150	9	excipient	excipient	NOUN
cuesj-1234	150	10	played	play	VERB
cuesj-1234	150	11	a	a	DET
cuesj-1234	150	12	bigger	big	ADJ
cuesj-1234	150	13	role	role	NOUN
cuesj-1234	150	14	in	in	ADP
cuesj-1234	150	15	the	the	DET
cuesj-1234	150	16	simvastatin	simvastatin	NOUN
cuesj-1234	150	17	’s	’s	PART
cuesj-1234	150	18	solubility	solubility	NOUN
cuesj-1234	150	19	or	or	CCONJ
cuesj-1234	150	20	lack	lack	NOUN
cuesj-1234	150	21	thereof	thereof	ADV
cuesj-1234	150	22	.	.	PUNCT
cuesj-1234	151	1	conclusion	conclusion	NOUN
cuesj-1234	151	2	in	in	ADP
cuesj-1234	151	3	this	this	DET
cuesj-1234	151	4	experiment	experiment	NOUN
cuesj-1234	151	5	,	,	PUNCT
cuesj-1234	151	6	simvastatin	simvastatin	PROPN
cuesj-1234	151	7	was	be	AUX
cuesj-1234	151	8	incorporated	incorporate	VERB
cuesj-1234	151	9	into	into	ADP
cuesj-1234	151	10	a	a	DET
cuesj-1234	151	11	solid	solid	ADJ
cuesj-1234	151	12	dispersion	dispersion	NOUN
cuesj-1234	151	13	of	of	ADP
cuesj-1234	151	14	docusate	docusate	NOUN
cuesj-1234	151	15	and	and	CCONJ
cuesj-1234	151	16	isoleucine	isoleucine	NOUN
cuesj-1234	151	17	to	to	PART
cuesj-1234	151	18	improve	improve	VERB
cuesj-1234	151	19	its	its	PRON
cuesj-1234	151	20	solubility	solubility	NOUN
cuesj-1234	151	21	.	.	PUNCT
cuesj-1234	152	1	the	the	DET
cuesj-1234	152	2	best	good	ADJ
cuesj-1234	152	3	improvement	improvement	NOUN
cuesj-1234	152	4	had	have	VERB
cuesj-1234	152	5	a	a	DET
cuesj-1234	152	6	7	7	ADJ
cuesj-1234	152	7	-	-	ADJ
cuesj-1234	152	8	fold	fold	ADJ
cuesj-1234	152	9	increase	increase	NOUN
cuesj-1234	152	10	from	from	ADP
cuesj-1234	152	11	normal	normal	ADJ
cuesj-1234	152	12	simvastatin	simvastatin	NOUN
cuesj-1234	152	13	,	,	PUNCT
cuesj-1234	152	14	with	with	ADP
cuesj-1234	152	15	1.5	1.5	NUM
cuesj-1234	152	16	-	-	ADJ
cuesj-1234	152	17	fold	fold	ADJ
cuesj-1234	152	18	being	be	AUX
cuesj-1234	152	19	the	the	DET
cuesj-1234	152	20	lowest	low	ADJ
cuesj-1234	152	21	improvement	improvement	NOUN
cuesj-1234	152	22	.	.	PUNCT
cuesj-1234	153	1	the	the	DET
cuesj-1234	153	2	best	good	ADJ
cuesj-1234	153	3	improvement	improvement	NOUN
cuesj-1234	153	4	corresponds	correspond	VERB
cuesj-1234	153	5	with	with	ADP
cuesj-1234	153	6	a	a	DET
cuesj-1234	153	7	2:1:1	2:1:1	NUM
cuesj-1234	153	8	ratio	ratio	NOUN
cuesj-1234	153	9	of	of	ADP
cuesj-1234	153	10	simvastatin	simvastatin	NOUN
cuesj-1234	153	11	and	and	CCONJ
cuesj-1234	153	12	excipients	excipient	NOUN
cuesj-1234	153	13	.	.	PUNCT
cuesj-1234	154	1	these	these	DET
cuesj-1234	154	2	results	result	NOUN
cuesj-1234	154	3	indicate	indicate	VERB
cuesj-1234	154	4	that	that	SCONJ
cuesj-1234	154	5	the	the	DET
cuesj-1234	154	6	surfactant	surfactant	ADJ
cuesj-1234	154	7	properties	property	NOUN
cuesj-1234	154	8	of	of	ADP
cuesj-1234	154	9	docusate	docusate	NOUN
cuesj-1234	154	10	in	in	ADP
cuesj-1234	154	11	conjugation	conjugation	NOUN
cuesj-1234	154	12	with	with	ADP
cuesj-1234	154	13	isoleucine	isoleucine	PROPN
cuesj-1234	154	14	improve	improve	VERB
cuesj-1234	154	15	the	the	DET
cuesj-1234	154	16	solubility	solubility	NOUN
cuesj-1234	154	17	of	of	ADP
cuesj-1234	154	18	simvastatin	simvastatin	NOUN
cuesj-1234	154	19	to	to	ADP
cuesj-1234	154	20	a	a	DET
cuesj-1234	154	21	large	large	ADJ
cuesj-1234	154	22	degree	degree	NOUN
cuesj-1234	154	23	.	.	PUNCT
cuesj-1234	155	1	this	this	DET
cuesj-1234	155	2	combination	combination	NOUN
cuesj-1234	155	3	is	be	AUX
cuesj-1234	155	4	optimized	optimize	VERB
cuesj-1234	155	5	when	when	SCONJ
cuesj-1234	155	6	the	the	DET
cuesj-1234	155	7	ratio	ratio	NOUN
cuesj-1234	155	8	of	of	ADP
cuesj-1234	155	9	excipients	excipient	NOUN
cuesj-1234	155	10	is	be	AUX
cuesj-1234	155	11	relatively	relatively	ADV
cuesj-1234	155	12	low	low	ADJ
cuesj-1234	155	13	compared	compare	VERB
cuesj-1234	155	14	to	to	ADP
cuesj-1234	155	15	the	the	DET
cuesj-1234	155	16	mass	mass	NOUN
cuesj-1234	155	17	of	of	ADP
cuesj-1234	155	18	simvastatin	simvastatin	NOUN
cuesj-1234	155	19	.	.	PUNCT
cuesj-1234	156	1	in	in	ADP
cuesj-1234	156	2	future	future	NOUN
cuesj-1234	156	3	,	,	PUNCT
cuesj-1234	156	4	a	a	DET
cuesj-1234	156	5	study	study	NOUN
cuesj-1234	156	6	can	can	AUX
cuesj-1234	156	7	be	be	AUX
cuesj-1234	156	8	done	do	VERB
cuesj-1234	156	9	that	that	PRON
cuesj-1234	156	10	replaces	replace	VERB
cuesj-1234	156	11	the	the	DET
cuesj-1234	156	12	solvent	solvent	NOUN
cuesj-1234	156	13	with	with	ADP
cuesj-1234	156	14	something	something	PRON
cuesj-1234	156	15	similar	similar	ADJ
cuesj-1234	156	16	,	,	PUNCT
cuesj-1234	156	17	or	or	CCONJ
cuesj-1234	156	18	the	the	DET
cuesj-1234	156	19	sodium	sodium	NOUN
cuesj-1234	156	20	docusate	docusate	NOUN
cuesj-1234	156	21	with	with	ADP
cuesj-1234	156	22	a	a	DET
cuesj-1234	156	23	polymer	polymer	NOUN
cuesj-1234	156	24	surfactant	surfactant	NOUN
cuesj-1234	156	25	.	.	PUNCT
cuesj-1234	157	1	another	another	DET
cuesj-1234	157	2	measure	measure	NOUN
cuesj-1234	157	3	could	could	AUX
cuesj-1234	157	4	be	be	AUX
cuesj-1234	157	5	to	to	PART
cuesj-1234	157	6	calculate	calculate	VERB
cuesj-1234	157	7	how	how	SCONJ
cuesj-1234	157	8	much	much	ADJ
cuesj-1234	157	9	simvastatin	simvastatin	NOUN
cuesj-1234	157	10	is	be	AUX
cuesj-1234	157	11	found	find	VERB
cuesj-1234	157	12	per	per	ADP
cuesj-1234	157	13	milligram	milligram	NOUN
cuesj-1234	157	14	of	of	ADP
cuesj-1234	157	15	solid	solid	ADJ
cuesj-1234	157	16	dispersion	dispersion	NOUN
cuesj-1234	157	17	,	,	PUNCT
cuesj-1234	157	18	which	which	PRON
cuesj-1234	157	19	may	may	AUX
cuesj-1234	157	20	provide	provide	VERB
cuesj-1234	157	21	insight	insight	NOUN
cuesj-1234	157	22	into	into	ADP
cuesj-1234	157	23	the	the	DET
cuesj-1234	157	24	content	content	NOUN
cuesj-1234	157	25	of	of	ADP
cuesj-1234	157	26	each	each	DET
cuesj-1234	157	27	solution	solution	NOUN
cuesj-1234	157	28	,	,	PUNCT
cuesj-1234	157	29	and	and	CCONJ
cuesj-1234	157	30	how	how	SCONJ
cuesj-1234	157	31	much	much	ADJ
cuesj-1234	157	32	of	of	ADP
cuesj-1234	157	33	the	the	DET
cuesj-1234	157	34	mixture	mixture	NOUN
cuesj-1234	157	35	is	be	AUX
cuesj-1234	157	36	actually	actually	ADV
cuesj-1234	157	37	an	an	DET
cuesj-1234	157	38	active	active	ADJ
cuesj-1234	157	39	ingredient	ingredient	NOUN
cuesj-1234	157	40	.	.	PUNCT
cuesj-1234	158	1	acknowledgments	acknowledgment	NOUN
cuesj-1234	158	2	many	many	ADJ
cuesj-1234	158	3	thanks	thank	NOUN
cuesj-1234	158	4	to	to	ADP
cuesj-1234	158	5	dr	dr	PROPN
cuesj-1234	158	6	.	.	PROPN
cuesj-1234	158	7	idris	idris	PROPN
cuesj-1234	158	8	/	/	SYM
cuesj-1234	158	9	college	college	PROPN
cuesj-1234	158	10	of	of	ADP
cuesj-1234	158	11	pharmacy	pharmacy	NOUN
cuesj-1234	158	12	for	for	ADP
cuesj-1234	158	13	allowing	allow	VERB
cuesj-1234	158	14	access	access	NOUN
cuesj-1234	158	15	to	to	ADP
cuesj-1234	158	16	the	the	DET
cuesj-1234	158	17	research	research	NOUN
cuesj-1234	158	18	laboratory	laboratory	NOUN
cuesj-1234	158	19	and	and	CCONJ
cuesj-1234	158	20	the	the	DET
cuesj-1234	158	21	instruments	instrument	NOUN
cuesj-1234	158	22	and	and	CCONJ
cuesj-1234	158	23	materials	material	NOUN
cuesj-1234	158	24	required	require	VERB
cuesj-1234	158	25	for	for	ADP
cuesj-1234	158	26	this	this	DET
cuesj-1234	158	27	experiment	experiment	NOUN
cuesj-1234	158	28	.	.	PUNCT
cuesj-1234	159	1	references	reference	NOUN
cuesj-1234	159	2	1	1	NUM
cuesj-1234	159	3	.	.	PUNCT
cuesj-1234	159	4	e.	e.	PROPN
cuesj-1234	159	5	rinaki	rinaki	PROPN
cuesj-1234	159	6	,	,	PUNCT
cuesj-1234	159	7	g.	g.	PROPN
cuesj-1234	159	8	valsami	valsami	NOUN
cuesj-1234	159	9	and	and	CCONJ
cuesj-1234	159	10	p.	p.	PROPN
cuesj-1234	159	11	macheras	macheras	PROPN
cuesj-1234	159	12	.	.	PUNCT
cuesj-1234	160	1	quantitative	quantitative	ADJ
cuesj-1234	160	2	biopharmaceutics	biopharmaceutics	NOUN
cuesj-1234	160	3	classification	classification	NOUN
cuesj-1234	160	4	system	system	NOUN
cuesj-1234	160	5	:	:	PUNCT
cuesj-1234	160	6	the	the	DET
cuesj-1234	160	7	central	central	ADJ
cuesj-1234	160	8	role	role	NOUN
cuesj-1234	160	9	of	of	ADP
cuesj-1234	160	10	dose	dose	NOUN
cuesj-1234	160	11	/	/	SYM
cuesj-1234	160	12	solubility	solubility	NOUN
cuesj-1234	160	13	ratio	ratio	NOUN
cuesj-1234	160	14	.	.	PUNCT
cuesj-1234	161	1	pharmaceutical	pharmaceutical	ADJ
cuesj-1234	161	2	research	research	NOUN
cuesj-1234	161	3	,	,	PUNCT
cuesj-1234	161	4	vol	vol	NOUN
cuesj-1234	161	5	.	.	PROPN
cuesj-1234	161	6	20	20	NUM
cuesj-1234	161	7	,	,	PUNCT
cuesj-1234	161	8	no	no	INTJ
cuesj-1234	161	9	.	.	NOUN
cuesj-1234	161	10	12	12	NUM
cuesj-1234	161	11	,	,	PUNCT
cuesj-1234	161	12	pp	pp	ADJ
cuesj-1234	161	13	.	.	PUNCT
cuesj-1234	161	14	1917	1917	NUM
cuesj-1234	161	15	-	-	SYM
cuesj-1234	161	16	1925	1925	NUM
cuesj-1234	161	17	,	,	PUNCT
cuesj-1234	161	18	2003	2003	NUM
cuesj-1234	161	19	.	.	PUNCT
cuesj-1234	162	1	2	2	X
cuesj-1234	162	2	.	.	X
cuesj-1234	162	3	m.	m.	PROPN
cuesj-1234	162	4	lindenberg	lindenberg	PROPN
cuesj-1234	162	5	,	,	PUNCT
cuesj-1234	162	6	s.	s.	PROPN
cuesj-1234	162	7	kopp	kopp	PROPN
cuesj-1234	162	8	and	and	CCONJ
cuesj-1234	162	9	j.	j.	PROPN
cuesj-1234	162	10	b.	b.	PROPN
cuesj-1234	162	11	dressman	dressman	PROPN
cuesj-1234	162	12	.	.	PUNCT
cuesj-1234	163	1	classification	classification	NOUN
cuesj-1234	163	2	of	of	ADP
cuesj-1234	163	3	orally	orally	ADV
cuesj-1234	163	4	administered	administer	VERB
cuesj-1234	163	5	drugs	drug	NOUN
cuesj-1234	163	6	on	on	ADP
cuesj-1234	163	7	the	the	DET
cuesj-1234	163	8	world	world	PROPN
cuesj-1234	163	9	health	health	PROPN
cuesj-1234	163	10	organization	organization	PROPN
cuesj-1234	163	11	model	model	NOUN
cuesj-1234	163	12	list	list	NOUN
cuesj-1234	163	13	of	of	ADP
cuesj-1234	163	14	essential	essential	ADJ
cuesj-1234	163	15	medicines	medicine	NOUN
cuesj-1234	163	16	according	accord	VERB
cuesj-1234	163	17	to	to	ADP
cuesj-1234	163	18	the	the	DET
cuesj-1234	163	19	biopharmaceutics	biopharmaceutics	NOUN
cuesj-1234	163	20	classification	classification	NOUN
cuesj-1234	163	21	system	system	NOUN
cuesj-1234	163	22	.	.	PUNCT
cuesj-1234	164	1	european	european	PROPN
cuesj-1234	164	2	journal	journal	PROPN
cuesj-1234	164	3	pharmaceutics	pharmaceutic	NOUN
cuesj-1234	164	4	biopharmaceutics	biopharmaceutics	PROPN
cuesj-1234	164	5	,	,	PUNCT
cuesj-1234	164	6	vol	vol	NOUN
cuesj-1234	164	7	.	.	PROPN
cuesj-1234	165	1	58	58	NUM
cuesj-1234	165	2	,	,	PUNCT
cuesj-1234	165	3	no	no	INTJ
cuesj-1234	165	4	.	.	NOUN
cuesj-1234	165	5	2	2	NUM
cuesj-1234	165	6	,	,	PUNCT
cuesj-1234	165	7	pp	pp	ADJ
cuesj-1234	165	8	.	.	PUNCT
cuesj-1234	166	1	265	265	NUM
cuesj-1234	166	2	-	-	SYM
cuesj-1234	166	3	278	278	NUM
cuesj-1234	166	4	,	,	PUNCT
cuesj-1234	166	5	2004	2004	NUM
cuesj-1234	166	6	.	.	PUNCT
cuesj-1234	167	1	3	3	X
cuesj-1234	167	2	.	.	X
cuesj-1234	167	3	d.	d.	PROPN
cuesj-1234	167	4	m.	m.	PROPN
cuesj-1234	167	5	shackleford	shackleford	PROPN
cuesj-1234	167	6	,	,	PUNCT
cuesj-1234	167	7	c.	c.	PROPN
cuesj-1234	167	8	j.	j.	PROPN
cuesj-1234	167	9	h.	h.	PROPN
cuesj-1234	167	10	porter	porter	PROPN
cuesj-1234	167	11	and	and	CCONJ
cuesj-1234	167	12	w.	w.	PROPN
cuesj-1234	167	13	n.	n.	PROPN
cuesj-1234	167	14	charman	charman	PROPN
cuesj-1234	167	15	.	.	PUNCT
cuesj-1234	168	1	lymphatic	lymphatic	ADJ
cuesj-1234	168	2	absorption	absorption	NOUN
cuesj-1234	168	3	of	of	ADP
cuesj-1234	168	4	orally	orally	ADV
cuesj-1234	168	5	administered	administer	VERB
cuesj-1234	168	6	prodrugs	prodrug	NOUN
cuesj-1234	168	7	.	.	PUNCT
cuesj-1234	169	1	in	in	ADP
cuesj-1234	169	2	:	:	PUNCT
cuesj-1234	169	3	v.	v.	PROPN
cuesj-1234	169	4	j.	j.	PROPN
cuesj-1234	169	5	stella	stella	PROPN
cuesj-1234	169	6	,	,	PUNCT
cuesj-1234	169	7	r.	r.	PROPN
cuesj-1234	169	8	t.	t.	PROPN
cuesj-1234	169	9	borchardt	borchardt	PROPN
cuesj-1234	169	10	,	,	PUNCT
cuesj-1234	169	11	m.	m.	NOUN
cuesj-1234	169	12	j.	j.	PROPN
cuesj-1234	169	13	hageman	hageman	PROPN
cuesj-1234	169	14	,	,	PUNCT
cuesj-1234	169	15	r.	r.	PROPN
cuesj-1234	169	16	oliyai	oliyai	PROPN
cuesj-1234	169	17	,	,	PUNCT
cuesj-1234	169	18	h.	h.	PROPN
cuesj-1234	169	19	maag	maag	PROPN
cuesj-1234	169	20	and	and	CCONJ
cuesj-1234	169	21	j.	j.	PROPN
cuesj-1234	169	22	w.	w.	PROPN
cuesj-1234	169	23	tilley	tilley	PROPN
cuesj-1234	169	24	,	,	PUNCT
cuesj-1234	169	25	editors	editor	NOUN
cuesj-1234	169	26	.	.	PUNCT
cuesj-1234	169	27	prodrugs	prodrug	NOUN
cuesj-1234	169	28	:	:	PUNCT
cuesj-1234	169	29	challenges	challenge	NOUN
cuesj-1234	169	30	and	and	CCONJ
cuesj-1234	169	31	rewards	reward	VERB
cuesj-1234	169	32	part	part	NOUN
cuesj-1234	169	33	1	1	NUM
cuesj-1234	169	34	.	.	PUNCT
cuesj-1234	170	1	in	in	ADP
cuesj-1234	170	2	biotechnology	biotechnology	NOUN
cuesj-1234	170	3	:	:	PUNCT
cuesj-1234	170	4	pharmaceutical	pharmaceutical	NOUN
cuesj-1234	170	5	aspects	aspect	NOUN
cuesj-1234	170	6	.	.	PUNCT
cuesj-1234	171	1	springer	springer	NOUN
cuesj-1234	171	2	,	,	PUNCT
cuesj-1234	171	3	new	new	PROPN
cuesj-1234	171	4	york	york	PROPN
cuesj-1234	171	5	,	,	PUNCT
cuesj-1234	171	6	ny	ny	PROPN
cuesj-1234	171	7	,	,	PUNCT
cuesj-1234	171	8	pp	pp	PROPN
cuesj-1234	171	9	.	.	PUNCT
cuesj-1234	172	1	653	653	NUM
cuesj-1234	172	2	-	-	SYM
cuesj-1234	172	3	682	682	NUM
cuesj-1234	172	4	,	,	PUNCT
cuesj-1234	172	5	2007	2007	NUM
cuesj-1234	172	6	.	.	PUNCT
cuesj-1234	173	1	4	4	X
cuesj-1234	173	2	.	.	PUNCT
cuesj-1234	173	3	h.	h.	PROPN
cuesj-1234	173	4	d.	d.	PROPN
cuesj-1234	173	5	williams	williams	PROPN
cuesj-1234	173	6	,	,	PUNCT
cuesj-1234	173	7	n.	n.	PROPN
cuesj-1234	173	8	l.	l.	PROPN
cuesj-1234	173	9	trevaskis	trevaskis	PROPN
cuesj-1234	173	10	,	,	PUNCT
cuesj-1234	173	11	s.	s.	PROPN
cuesj-1234	173	12	a.	a.	PROPN
cuesj-1234	173	13	charman	charman	PROPN
cuesj-1234	173	14	,	,	PUNCT
cuesj-1234	173	15	r.	r.	PROPN
cuesj-1234	173	16	m.	m.	PROPN
cuesj-1234	173	17	shanker	shanker	PROPN
cuesj-1234	173	18	,	,	PUNCT
cuesj-1234	173	19	w.	w.	PROPN
cuesj-1234	173	20	n.	n.	PROPN
cuesj-1234	173	21	charman	charman	PROPN
cuesj-1234	173	22	,	,	PUNCT
cuesj-1234	173	23	c.	c.	PROPN
cuesj-1234	173	24	w.	w.	PROPN
cuesj-1234	173	25	pouton	pouton	PROPN
cuesj-1234	173	26	and	and	CCONJ
cuesj-1234	173	27	c.	c.	PROPN
cuesj-1234	173	28	j.	j.	PROPN
cuesj-1234	173	29	h.	h.	PROPN
cuesj-1234	173	30	porter	porter	PROPN
cuesj-1234	173	31	.	.	PUNCT
cuesj-1234	174	1	strategies	strategy	NOUN
cuesj-1234	174	2	to	to	PART
cuesj-1234	174	3	address	address	VERB
cuesj-1234	174	4	low	low	ADJ
cuesj-1234	174	5	drug	drug	NOUN
cuesj-1234	174	6	solubility	solubility	NOUN
cuesj-1234	174	7	in	in	ADP
cuesj-1234	174	8	discovery	discovery	NOUN
cuesj-1234	174	9	and	and	CCONJ
cuesj-1234	174	10	development	development	NOUN
cuesj-1234	174	11	.	.	PUNCT
cuesj-1234	175	1	pharmacological	pharmacological	ADJ
cuesj-1234	175	2	review	review	NOUN
cuesj-1234	175	3	,	,	PUNCT
cuesj-1234	175	4	vol	vol	NOUN
cuesj-1234	175	5	.	.	PROPN
cuesj-1234	175	6	65	65	NUM
cuesj-1234	175	7	,	,	PUNCT
cuesj-1234	175	8	no	no	INTJ
cuesj-1234	175	9	.	.	NOUN
cuesj-1234	175	10	1	1	NUM
cuesj-1234	175	11	,	,	PUNCT
cuesj-1234	175	12	pp	pp	ADJ
cuesj-1234	175	13	.	.	PUNCT
cuesj-1234	176	1	315	315	NUM
cuesj-1234	176	2	-	-	SYM
cuesj-1234	176	3	499	499	NUM
cuesj-1234	176	4	,	,	PUNCT
cuesj-1234	176	5	2013	2013	NUM
cuesj-1234	176	6	.	.	PUNCT
cuesj-1234	177	1	5	5	NUM
cuesj-1234	177	2	.	.	PUNCT
cuesj-1234	177	3	g.	g.	PROPN
cuesj-1234	177	4	l.	l.	PROPN
cuesj-1234	177	5	amidon	amidon	PROPN
cuesj-1234	177	6	,	,	PUNCT
cuesj-1234	177	7	h.	h.	PROPN
cuesj-1234	177	8	lennernäs	lennernäs	PROPN
cuesj-1234	177	9	,	,	PUNCT
cuesj-1234	177	10	v.	v.	ADP
cuesj-1234	177	11	p.	p.	NOUN
cuesj-1234	177	12	shah	shah	PROPN
cuesj-1234	177	13	and	and	CCONJ
cuesj-1234	177	14	j.	j.	PROPN
cuesj-1234	177	15	r.	r.	PROPN
cuesj-1234	177	16	crison	crison	PROPN
cuesj-1234	177	17	.	.	PUNCT
cuesj-1234	178	1	a	a	DET
cuesj-1234	178	2	theoretical	theoretical	ADJ
cuesj-1234	178	3	basis	basis	NOUN
cuesj-1234	178	4	for	for	ADP
cuesj-1234	178	5	a	a	DET
cuesj-1234	178	6	biopharmaceutic	biopharmaceutic	ADJ
cuesj-1234	178	7	drug	drug	NOUN
cuesj-1234	178	8	classification	classification	NOUN
cuesj-1234	178	9	:	:	PUNCT
cuesj-1234	178	10	the	the	DET
cuesj-1234	178	11	correlation	correlation	NOUN
cuesj-1234	178	12	of	of	ADP
cuesj-1234	178	13	in	in	ADP
cuesj-1234	178	14	vitro	vitro	X
cuesj-1234	178	15	drug	drug	NOUN
cuesj-1234	178	16	product	product	NOUN
cuesj-1234	178	17	dissolution	dissolution	NOUN
cuesj-1234	178	18	and	and	CCONJ
cuesj-1234	178	19	in	in	ADP
cuesj-1234	178	20	vivo	vivo	ADJ
cuesj-1234	178	21	bioavailability	bioavailability	NOUN
cuesj-1234	178	22	.	.	PUNCT
cuesj-1234	179	1	pharmaceutical	pharmaceutical	ADJ
cuesj-1234	179	2	research	research	NOUN
cuesj-1234	179	3	,	,	PUNCT
cuesj-1234	179	4	vol	vol	NOUN
cuesj-1234	179	5	.	.	PROPN
cuesj-1234	179	6	12	12	NUM
cuesj-1234	179	7	,	,	PUNCT
cuesj-1234	179	8	no	no	INTJ
cuesj-1234	179	9	.	.	NOUN
cuesj-1234	179	10	3	3	NUM
cuesj-1234	179	11	,	,	PUNCT
cuesj-1234	179	12	pp	pp	ADJ
cuesj-1234	179	13	.	.	PUNCT
cuesj-1234	179	14	413420	413420	NUM
cuesj-1234	179	15	,	,	PUNCT
cuesj-1234	179	16	1995	1995	NUM
cuesj-1234	179	17	.	.	PUNCT
cuesj-1234	180	1	6	6	NUM
cuesj-1234	180	2	.	.	X
cuesj-1234	180	3	m.	m.	NOUN
cuesj-1234	180	4	k.	k.	PROPN
cuesj-1234	180	5	vadlamudi	vadlamudi	PROPN
cuesj-1234	180	6	and	and	CCONJ
cuesj-1234	180	7	s.	s.	PROPN
cuesj-1234	180	8	dhanaraj	dhanaraj	PROPN
cuesj-1234	180	9	.	.	PUNCT
cuesj-1234	181	1	significance	significance	NOUN
cuesj-1234	181	2	of	of	ADP
cuesj-1234	181	3	excipients	excipient	NOUN
cuesj-1234	181	4	to	to	PART
cuesj-1234	181	5	enhance	enhance	VERB
cuesj-1234	181	6	the	the	DET
cuesj-1234	181	7	bioavailability	bioavailability	NOUN
cuesj-1234	181	8	of	of	ADP
cuesj-1234	181	9	poorly	poorly	ADV
cuesj-1234	181	10	water	water	NOUN
cuesj-1234	181	11	-	-	PUNCT
cuesj-1234	181	12	soluble	soluble	ADJ
cuesj-1234	181	13	drugs	drug	NOUN
cuesj-1234	181	14	in	in	ADP
cuesj-1234	181	15	oral	oral	ADJ
cuesj-1234	181	16	solid	solid	ADJ
cuesj-1234	181	17	dosage	dosage	NOUN
cuesj-1234	181	18	forms	form	NOUN
cuesj-1234	181	19	:	:	PUNCT
cuesj-1234	181	20	a	a	DET
cuesj-1234	181	21	review	review	NOUN
cuesj-1234	181	22	.	.	PUNCT
cuesj-1234	182	1	iop	iop	PROPN
cuesj-1234	182	2	conference	conference	PROPN
cuesj-1234	182	3	series	series	PROPN
cuesj-1234	182	4	materials	material	NOUN
cuesj-1234	182	5	science	science	NOUN
cuesj-1234	182	6	engineering	engineering	NOUN
cuesj-1234	182	7	,	,	PUNCT
cuesj-1234	182	8	vol	vol	NOUN
cuesj-1234	182	9	.	.	PROPN
cuesj-1234	182	10	263	263	NUM
cuesj-1234	182	11	,	,	PUNCT
cuesj-1234	182	12	p.	p.	NOUN
cuesj-1234	182	13	022023	022023	NUM
cuesj-1234	182	14	,	,	PUNCT
cuesj-1234	182	15	2017	2017	NUM
cuesj-1234	182	16	.	.	PUNCT
cuesj-1234	183	1	7	7	X
cuesj-1234	183	2	.	.	X
cuesj-1234	183	3	n.	n.	PROPN
cuesj-1234	183	4	singh	singh	PROPN
cuesj-1234	183	5	,	,	PUNCT
cuesj-1234	183	6	a.	a.	NOUN
cuesj-1234	183	7	p.	p.	NOUN
cuesj-1234	183	8	singh	singh	PROPN
cuesj-1234	183	9	and	and	CCONJ
cuesj-1234	183	10	a.	a.	NOUN
cuesj-1234	183	11	p.	p.	PROPN
cuesj-1234	183	12	singh	singh	PROPN
cuesj-1234	183	13	.	.	PUNCT
cuesj-1234	184	1	(	(	PUNCT
cuesj-1234	184	2	pdf	pdf	NOUN
cuesj-1234	184	3	)	)	PUNCT
cuesj-1234	184	4	solubility	solubility	NOUN
cuesj-1234	184	5	:	:	PUNCT
cuesj-1234	184	6	an	an	DET
cuesj-1234	184	7	overview	overview	NOUN
cuesj-1234	184	8	.	.	PUNCT
cuesj-1234	185	1	international	international	ADJ
cuesj-1234	185	2	journal	journal	PROPN
cuesj-1234	185	3	pharmaceutical	pharmaceutical	ADJ
cuesj-1234	185	4	chemistry	chemistry	NOUN
cuesj-1234	185	5	analysis	analysis	NOUN
cuesj-1234	185	6	,	,	PUNCT
cuesj-1234	185	7	vol	vol	NOUN
cuesj-1234	185	8	.	.	PROPN
cuesj-1234	185	9	7	7	NUM
cuesj-1234	185	10	,	,	PUNCT
cuesj-1234	185	11	no	no	INTJ
cuesj-1234	185	12	.	.	NOUN
cuesj-1234	185	13	4	4	NUM
cuesj-1234	185	14	,	,	PUNCT
cuesj-1234	185	15	pp	pp	ADJ
cuesj-1234	185	16	.	.	PUNCT
cuesj-1234	186	1	166	166	NUM
cuesj-1234	186	2	-	-	SYM
cuesj-1234	186	3	171	171	NUM
cuesj-1234	186	4	,	,	PUNCT
cuesj-1234	186	5	2021	2021	NUM
cuesj-1234	186	6	.	.	PUNCT
cuesj-1234	187	1	8	8	X
cuesj-1234	187	2	.	.	X
cuesj-1234	188	1	v.	v.	PROPN
cuesj-1234	188	2	f.	f.	PROPN
cuesj-1234	188	3	mauro	mauro	PROPN
cuesj-1234	188	4	and	and	CCONJ
cuesj-1234	188	5	j.	j.	PROPN
cuesj-1234	188	6	l.	l.	PROPN
cuesj-1234	188	7	macdonald	macdonald	PROPN
cuesj-1234	188	8	.	.	PUNCT
cuesj-1234	189	1	simvastatin	simvastatin	PROPN
cuesj-1234	189	2	:	:	PUNCT
cuesj-1234	189	3	a	a	DET
cuesj-1234	189	4	review	review	NOUN
cuesj-1234	189	5	of	of	ADP
cuesj-1234	189	6	its	its	PRON
cuesj-1234	189	7	pharmacology	pharmacology	NOUN
cuesj-1234	189	8	and	and	CCONJ
cuesj-1234	189	9	clinical	clinical	ADJ
cuesj-1234	189	10	use	use	NOUN
cuesj-1234	189	11	.	.	PUNCT
cuesj-1234	190	1	dicp	dicp	NOUN
cuesj-1234	190	2	,	,	PUNCT
cuesj-1234	190	3	vol	vol	NOUN
cuesj-1234	190	4	.	.	PROPN
cuesj-1234	191	1	25	25	NUM
cuesj-1234	191	2	,	,	PUNCT
cuesj-1234	191	3	no	no	INTJ
cuesj-1234	191	4	.	.	NOUN
cuesj-1234	191	5	3	3	NUM
cuesj-1234	191	6	,	,	PUNCT
cuesj-1234	191	7	pp	pp	ADJ
cuesj-1234	191	8	.	.	PUNCT
cuesj-1234	192	1	257	257	NUM
cuesj-1234	192	2	-	-	SYM
cuesj-1234	192	3	264	264	NUM
cuesj-1234	192	4	,	,	PUNCT
cuesj-1234	192	5	1991	1991	NUM
cuesj-1234	192	6	.	.	PUNCT
cuesj-1234	193	1	9	9	X
cuesj-1234	193	2	.	.	X
cuesj-1234	193	3	d.	d.	PROPN
cuesj-1234	193	4	k.	k.	PROPN
cuesj-1234	193	5	ellison	ellison	PROPN
cuesj-1234	193	6	,	,	PUNCT
cuesj-1234	193	7	w.	w.	PROPN
cuesj-1234	193	8	d.	d.	PROPN
cuesj-1234	193	9	moore	moore	PROPN
cuesj-1234	193	10	and	and	CCONJ
cuesj-1234	193	11	c.	c.	PROPN
cuesj-1234	193	12	r.	r.	PROPN
cuesj-1234	193	13	petts	petts	PROPN
cuesj-1234	193	14	.	.	PUNCT
cuesj-1234	194	1	simvastatin	simvastatin	PROPN
cuesj-1234	194	2	.	.	PUNCT
cuesj-1234	195	1	in	in	ADP
cuesj-1234	195	2	:	:	PUNCT
cuesj-1234	195	3	h.	h.	PROPN
cuesj-1234	195	4	g.	g.	PROPN
cuesj-1234	195	5	brittain	brittain	PROPN
cuesj-1234	195	6	,	,	PUNCT
cuesj-1234	195	7	editor	editor	NOUN
cuesj-1234	195	8	.	.	PUNCT
cuesj-1234	196	1	analytical	analytical	ADJ
cuesj-1234	196	2	profiles	profile	NOUN
cuesj-1234	196	3	of	of	ADP
cuesj-1234	196	4	drug	drug	NOUN
cuesj-1234	196	5	substances	substance	NOUN
cuesj-1234	196	6	and	and	CCONJ
cuesj-1234	196	7	excipients	excipient	NOUN
cuesj-1234	196	8	.	.	PUNCT
cuesj-1234	197	1	vol	vol	NOUN
cuesj-1234	197	2	.	.	PUNCT
cuesj-1234	198	1	22	22	NUM
cuesj-1234	198	2	.	.	PUNCT
cuesj-1234	199	1	academic	academic	ADJ
cuesj-1234	199	2	press	press	NOUN
cuesj-1234	199	3	,	,	PUNCT
cuesj-1234	199	4	united	united	PROPN
cuesj-1234	199	5	states	states	PROPN
cuesj-1234	199	6	,	,	PUNCT
cuesj-1234	199	7	pp	pp	ADV
cuesj-1234	199	8	.	.	PUNCT
cuesj-1234	200	1	359	359	NUM
cuesj-1234	200	2	-	-	SYM
cuesj-1234	200	3	388	388	NUM
cuesj-1234	200	4	,	,	PUNCT
cuesj-1234	200	5	1993	1993	NUM
cuesj-1234	200	6	.	.	PUNCT
cuesj-1234	201	1	10	10	NUM
cuesj-1234	201	2	.	.	PUNCT
cuesj-1234	201	3	a.	a.	NOUN
cuesj-1234	201	4	t.	t.	PROPN
cuesj-1234	201	5	serajuddin	serajuddin	PROPN
cuesj-1234	201	6	,	,	PUNCT
cuesj-1234	201	7	s.	s.	PROPN
cuesj-1234	201	8	a.	a.	PROPN
cuesj-1234	201	9	ranadive	ranadive	PROPN
cuesj-1234	201	10	and	and	CCONJ
cuesj-1234	201	11	e.	e.	PROPN
cuesj-1234	201	12	m.	m.	PROPN
cuesj-1234	201	13	mahoney	mahoney	PROPN
cuesj-1234	201	14	.	.	PUNCT
cuesj-1234	202	1	relative	relative	ADJ
cuesj-1234	202	2	lipophilicities	lipophilicitie	NOUN
cuesj-1234	202	3	,	,	PUNCT
cuesj-1234	202	4	solubilities	solubility	NOUN
cuesj-1234	202	5	,	,	PUNCT
cuesj-1234	202	6	and	and	CCONJ
cuesj-1234	202	7	structure	structure	NOUN
cuesj-1234	202	8	-	-	PUNCT
cuesj-1234	202	9	pharmacological	pharmacological	ADJ
cuesj-1234	202	10	considerations	consideration	NOUN
cuesj-1234	202	11	of	of	ADP
cuesj-1234	202	12	3	3	NUM
cuesj-1234	202	13	-	-	PUNCT
cuesj-1234	202	14	hydroxy-3	hydroxy-3	NUM
cuesj-1234	202	15	-	-	PUNCT
cuesj-1234	202	16	methylglutaryl	methylglutaryl	NOUN
cuesj-1234	202	17	-	-	PUNCT
cuesj-1234	202	18	coenzyme	coenzyme	PROPN
cuesj-1234	202	19	a	a	PRON
cuesj-1234	202	20	(	(	PUNCT
cuesj-1234	202	21	hmgcoa	hmgcoa	NOUN
cuesj-1234	202	22	)	)	PUNCT
cuesj-1234	202	23	reductase	reductase	NOUN
cuesj-1234	202	24	inhibitors	inhibitor	NOUN
cuesj-1234	202	25	pravastatin	pravastatin	NOUN
cuesj-1234	202	26	,	,	PUNCT
cuesj-1234	202	27	lovastatin	lovastatin	PROPN
cuesj-1234	202	28	,	,	PUNCT
cuesj-1234	202	29	mevastatin	mevastatin	NOUN
cuesj-1234	202	30	,	,	PUNCT
cuesj-1234	202	31	and	and	CCONJ
cuesj-1234	202	32	simvastatin	simvastatin	PROPN
cuesj-1234	202	33	.	.	PROPN
cuesj-1234	203	1	journal	journal	PROPN
cuesj-1234	203	2	pharmaceutical	pharmaceutical	NOUN
cuesj-1234	203	3	science	science	PROPN
cuesj-1234	203	4	,	,	PUNCT
cuesj-1234	203	5	vol	vol	NOUN
cuesj-1234	203	6	.	.	PROPN
cuesj-1234	203	7	80	80	NUM
cuesj-1234	203	8	,	,	PUNCT
cuesj-1234	203	9	no	no	INTJ
cuesj-1234	203	10	.	.	NOUN
cuesj-1234	203	11	9	9	NUM
cuesj-1234	203	12	,	,	PUNCT
cuesj-1234	203	13	pp	pp	ADJ
cuesj-1234	203	14	.	.	PUNCT
cuesj-1234	204	1	830	830	NUM
cuesj-1234	204	2	-	-	SYM
cuesj-1234	204	3	834	834	NUM
cuesj-1234	204	4	,	,	PUNCT
cuesj-1234	204	5	1991	1991	NUM
cuesj-1234	204	6	.	.	PUNCT
cuesj-1234	205	1	11	11	NUM
cuesj-1234	205	2	.	.	PUNCT
cuesj-1234	206	1	t.	t.	PROPN
cuesj-1234	206	2	jiang	jiang	PROPN
cuesj-1234	206	3	,	,	PUNCT
cuesj-1234	206	4	n.	n.	PROPN
cuesj-1234	206	5	han	han	PROPN
cuesj-1234	206	6	,	,	PUNCT
cuesj-1234	206	7	b.	b.	PROPN
cuesj-1234	206	8	zhao	zhao	PROPN
cuesj-1234	206	9	,	,	PUNCT
cuesj-1234	206	10	y.	y.	PROPN
cuesj-1234	206	11	xie	xie	PROPN
cuesj-1234	206	12	and	and	CCONJ
cuesj-1234	206	13	s.	s.	PROPN
cuesj-1234	206	14	wang	wang	PROPN
cuesj-1234	206	15	.	.	PUNCT
cuesj-1234	206	16	enhanced	enhance	VERB
cuesj-1234	206	17	dissolution	dissolution	NOUN
cuesj-1234	206	18	rate	rate	NOUN
cuesj-1234	206	19	and	and	CCONJ
cuesj-1234	206	20	oral	oral	ADJ
cuesj-1234	206	21	bioavailability	bioavailability	NOUN
cuesj-1234	206	22	of	of	ADP
cuesj-1234	206	23	simvastatin	simvastatin	PROPN
cuesj-1234	206	24	nanocrystal	nanocrystal	PROPN
cuesj-1234	206	25	prepared	prepare	VERB
cuesj-1234	206	26	by	by	ADP
cuesj-1234	206	27	sonoprecipitation	sonoprecipitation	PROPN
cuesj-1234	206	28	.	.	PUNCT
cuesj-1234	207	1	drug	drug	PROPN
cuesj-1234	207	2	development	development	PROPN
cuesj-1234	207	3	industrial	industrial	PROPN
cuesj-1234	207	4	pharmacy	pharmacy	NOUN
cuesj-1234	207	5	,	,	PUNCT
cuesj-1234	207	6	vol	vol	NOUN
cuesj-1234	207	7	.	.	PROPN
cuesj-1234	208	1	38	38	NUM
cuesj-1234	208	2	,	,	PUNCT
cuesj-1234	208	3	no	no	INTJ
cuesj-1234	208	4	.	.	NOUN
cuesj-1234	208	5	10	10	NUM
cuesj-1234	208	6	,	,	PUNCT
cuesj-1234	208	7	pp	pp	ADJ
cuesj-1234	208	8	.	.	PUNCT
cuesj-1234	209	1	1230	1230	NUM
cuesj-1234	209	2	-	-	SYM
cuesj-1234	209	3	1239	1239	NUM
cuesj-1234	209	4	,	,	PUNCT
cuesj-1234	209	5	2012	2012	NUM
cuesj-1234	209	6	.	.	PUNCT
cuesj-1234	210	1	12	12	NUM
cuesj-1234	210	2	.	.	PUNCT
cuesj-1234	210	3	m.	m.	NOUN
cuesj-1234	210	4	j.	j.	PROPN
cuesj-1234	210	5	o’neil	o’neil	PROPN
cuesj-1234	210	6	.	.	PUNCT
cuesj-1234	211	1	simvastatin	simvastatin	PROPN
cuesj-1234	211	2	.	.	PUNCT
cuesj-1234	212	1	in	in	ADP
cuesj-1234	212	2	:	:	PUNCT
cuesj-1234	212	3	the	the	DET
cuesj-1234	212	4	merck	merck	PROPN
cuesj-1234	212	5	index	index	NOUN
cuesj-1234	212	6	an	an	DET
cuesj-1234	212	7	encyclopedia	encyclopedia	NOUN
cuesj-1234	212	8	of	of	ADP
cuesj-1234	212	9	chemicals	chemical	NOUN
cuesj-1234	212	10	,	,	PUNCT
cuesj-1234	212	11	drugs	drug	NOUN
cuesj-1234	212	12	,	,	PUNCT
cuesj-1234	212	13	and	and	CCONJ
cuesj-1234	212	14	biological	biological	ADJ
cuesj-1234	212	15	.	.	PUNCT
cuesj-1234	213	1	royal	royal	ADJ
cuesj-1234	213	2	society	society	NOUN
cuesj-1234	213	3	of	of	ADP
cuesj-1234	213	4	chemistry	chemistry	NOUN
cuesj-1234	213	5	,	,	PUNCT
cuesj-1234	213	6	uk	uk	PROPN
cuesj-1234	213	7	,	,	PUNCT
cuesj-1234	213	8	p.	p.	NOUN
cuesj-1234	213	9	1587	1587	NUM
cuesj-1234	213	10	,	,	PUNCT
cuesj-1234	213	11	2013	2013	NUM
cuesj-1234	213	12	.	.	PUNCT
cuesj-1234	214	1	13	13	NUM
cuesj-1234	214	2	.	.	PUNCT
cuesj-1234	215	1	nikita	nikita	PROPN
cuesj-1234	215	2	.	.	PUNCT
cuesj-1234	215	3	simvastatin	simvastatin	PROPN
cuesj-1234	215	4	sielc	sielc	PROPN
cuesj-1234	215	5	technologies	technologies	PROPN
cuesj-1234	215	6	.	.	PUNCT
cuesj-1234	216	1	available	available	ADJ
cuesj-1234	216	2	from	from	ADP
cuesj-1234	216	3	:	:	PUNCT
cuesj-1234	216	4	https://	https://	NOUN
cuesj-1234	216	5	sielc.com/simvastatin	sielc.com/simvastatin	NOUN
cuesj-1234	217	1	[	[	X
cuesj-1234	217	2	last	last	ADV
cuesj-1234	217	3	accessed	access	VERB
cuesj-1234	217	4	on	on	ADP
cuesj-1234	217	5	2023	2023	NUM
cuesj-1234	217	6	feb	feb	NOUN
cuesj-1234	217	7	28	28	NUM
cuesj-1234	217	8	]	]	PUNCT
cuesj-1234	217	9	.	.	PUNCT
cuesj-1234	218	1	14	14	NUM
cuesj-1234	218	2	.	.	PUNCT
cuesj-1234	219	1	s.	s.	PROPN
cuesj-1234	219	2	nave	nave	PROPN
cuesj-1234	219	3	,	,	PUNCT
cuesj-1234	219	4	j.	j.	PROPN
cuesj-1234	219	5	eastoe	eastoe	PROPN
cuesj-1234	219	6	and	and	CCONJ
cuesj-1234	219	7	j.	j.	PROPN
cuesj-1234	219	8	penfold	penfold	PROPN
cuesj-1234	219	9	.	.	PUNCT
cuesj-1234	220	1	what	what	PRON
cuesj-1234	220	2	is	be	AUX
cuesj-1234	220	3	so	so	ADV
cuesj-1234	220	4	special	special	ADJ
cuesj-1234	220	5	about	about	ADP
cuesj-1234	220	6	aerosol	aerosol	NOUN
cuesj-1234	220	7	-	-	PUNCT
cuesj-1234	220	8	ot	ot	NOUN
cuesj-1234	220	9	?	?	PROPN
cuesj-1234	220	10	1	1	NUM
cuesj-1234	220	11	.	.	PUNCT
cuesj-1234	220	12	aqueous	aqueous	ADJ
cuesj-1234	220	13	systems	system	NOUN
cuesj-1234	220	14	.	.	PUNCT
cuesj-1234	221	1	langmuir	langmuir	PROPN
cuesj-1234	221	2	,	,	PUNCT
cuesj-1234	221	3	vol	vol	NOUN
cuesj-1234	221	4	.	.	PROPN
cuesj-1234	221	5	16	16	NUM
cuesj-1234	221	6	,	,	PUNCT
cuesj-1234	221	7	no	no	INTJ
cuesj-1234	221	8	.	.	NOUN
cuesj-1234	221	9	23	23	NUM
cuesj-1234	221	10	,	,	PUNCT
cuesj-1234	221	11	pp	pp	ADJ
cuesj-1234	221	12	.	.	PUNCT
cuesj-1234	222	1	8733	8733	NUM
cuesj-1234	222	2	-	-	SYM
cuesj-1234	222	3	8740	8740	NUM
cuesj-1234	222	4	,	,	PUNCT
cuesj-1234	222	5	2000	2000	NUM
cuesj-1234	222	6	.	.	PUNCT
cuesj-1234	223	1	15	15	NUM
cuesj-1234	223	2	.	.	X
cuesj-1234	224	1	d.	d.	PROPN
cuesj-1234	224	2	k.	k.	PROPN
cuesj-1234	224	3	kaczmarek	kaczmarek	PROPN
cuesj-1234	224	4	,	,	PUNCT
cuesj-1234	224	5	t.	t.	PROPN
cuesj-1234	224	6	rzemieniecki	rzemieniecki	NOUN
cuesj-1234	224	7	,	,	PUNCT
cuesj-1234	224	8	k.	k.	PROPN
cuesj-1234	224	9	marcinkowska	marcinkowska	PROPN
cuesj-1234	224	10	and	and	CCONJ
cuesj-1234	224	11	j.	j.	PROPN
cuesj-1234	224	12	pernak	pernak	PROPN
cuesj-1234	224	13	.	.	PUNCT
cuesj-1234	225	1	synthesis	synthesis	NOUN
cuesj-1234	225	2	,	,	PUNCT
cuesj-1234	225	3	properties	property	NOUN
cuesj-1234	225	4	and	and	CCONJ
cuesj-1234	225	5	adjuvant	adjuvant	ADJ
cuesj-1234	225	6	activity	activity	NOUN
cuesj-1234	225	7	of	of	ADP
cuesj-1234	225	8	docusatebased	docusatebase	VERB
cuesj-1234	225	9	ionic	ionic	ADJ
cuesj-1234	225	10	liquids	liquid	NOUN
cuesj-1234	225	11	in	in	ADP
cuesj-1234	225	12	pesticide	pesticide	NOUN
cuesj-1234	225	13	formulations	formulation	NOUN
cuesj-1234	225	14	.	.	PUNCT
cuesj-1234	226	1	journal	journal	PROPN
cuesj-1234	226	2	industrial	industrial	ADJ
cuesj-1234	226	3	and	and	CCONJ
cuesj-1234	226	4	engineering	engineer	VERB
cuesj-1234	226	5	chemistry	chemistry	NOUN
cuesj-1234	226	6	,	,	PUNCT
cuesj-1234	226	7	vol	vol	NOUN
cuesj-1234	226	8	.	.	PROPN
cuesj-1234	226	9	78	78	NUM
cuesj-1234	226	10	,	,	PUNCT
cuesj-1234	226	11	pp	pp	ADJ
cuesj-1234	226	12	.	.	PUNCT
cuesj-1234	227	1	440	440	NUM
cuesj-1234	227	2	-	-	SYM
cuesj-1234	227	3	447	447	NUM
cuesj-1234	227	4	,	,	PUNCT
cuesj-1234	227	5	2019	2019	NUM
cuesj-1234	227	6	.	.	PUNCT
cuesj-1234	228	1	16	16	NUM
cuesj-1234	228	2	.	.	PUNCT
cuesj-1234	228	3	i.	i.	PROPN
cuesj-1234	228	4	ibrar	ibrar	PROPN
cuesj-1234	228	5	,	,	PUNCT
cuesj-1234	228	6	s.	s.	PROPN
cuesj-1234	228	7	yadav	yadav	PROPN
cuesj-1234	228	8	,	,	PUNCT
cuesj-1234	228	9	a.	a.	PROPN
cuesj-1234	228	10	altaee	altaee	PROPN
cuesj-1234	228	11	,	,	PUNCT
cuesj-1234	228	12	j.	j.	PROPN
cuesj-1234	228	13	safaei	safaei	PROPN
cuesj-1234	228	14	,	,	PUNCT
cuesj-1234	228	15	a.	a.	PROPN
cuesj-1234	228	16	k.	k.	PROPN
cuesj-1234	228	17	samal	samal	PROPN
cuesj-1234	228	18	,	,	PUNCT
cuesj-1234	228	19	s.	s.	PROPN
cuesj-1234	228	20	subbiah	subbiah	PROPN
cuesj-1234	228	21	,	,	PUNCT
cuesj-1234	228	22	g.	g.	PROPN
cuesj-1234	228	23	millar	millar	PROPN
cuesj-1234	228	24	,	,	PUNCT
cuesj-1234	228	25	p.	p.	NOUN
cuesj-1234	228	26	deka	deka	PROPN
cuesj-1234	228	27	and	and	CCONJ
cuesj-1234	228	28	j.	j.	PROPN
cuesj-1234	228	29	zhou	zhou	PROPN
cuesj-1234	228	30	.	.	PUNCT
cuesj-1234	229	1	sodium	sodium	NOUN
cuesj-1234	229	2	docusate	docusate	NOUN
cuesj-1234	229	3	as	as	ADP
cuesj-1234	229	4	a	a	DET
cuesj-1234	229	5	cleaning	clean	VERB
cuesj-1234	229	6	agent	agent	NOUN
cuesj-1234	229	7	for	for	ADP
cuesj-1234	229	8	forward	forward	ADJ
cuesj-1234	229	9	osmosis	osmosis	NOUN
cuesj-1234	229	10	membranes	membrane	NOUN
cuesj-1234	229	11	fouled	foul	VERB
cuesj-1234	229	12	by	by	ADP
cuesj-1234	229	13	landfill	landfill	NOUN
cuesj-1234	229	14	leachate	leachate	NOUN
cuesj-1234	229	15	wastewater	wastewater	NOUN
cuesj-1234	229	16	.	.	PUNCT
cuesj-1234	230	1	chemosphere	chemosphere	PROPN
cuesj-1234	230	2	,	,	PUNCT
cuesj-1234	230	3	vol	vol	NOUN
cuesj-1234	230	4	.	.	PROPN
cuesj-1234	230	5	308	308	NUM
cuesj-1234	230	6	,	,	PUNCT
cuesj-1234	230	7	p.	p.	NOUN
cuesj-1234	230	8	136237	136237	NUM
cuesj-1234	230	9	,	,	PUNCT
cuesj-1234	230	10	2022	2022	NUM
cuesj-1234	230	11	.	.	PUNCT
cuesj-1234	231	1	17	17	NUM
cuesj-1234	231	2	.	.	PUNCT
cuesj-1234	231	3	q.	q.	PROPN
cuesj-1234	231	4	jia	jia	PROPN
cuesj-1234	231	5	,	,	PUNCT
cuesj-1234	231	6	x.	x.	PROPN
cuesj-1234	231	7	ni	ni	PROPN
cuesj-1234	231	8	and	and	CCONJ
cuesj-1234	231	9	z.	z.	PROPN
cuesj-1234	231	10	li	li	PROPN
cuesj-1234	231	11	.	.	PROPN
cuesj-1234	231	12	physical	physical	ADJ
cuesj-1234	231	13	and	and	CCONJ
cuesj-1234	231	14	chemical	chemical	NOUN
cuesj-1234	231	15	characteristics	characteristic	NOUN
cuesj-1234	231	16	of	of	ADP
cuesj-1234	231	17	anionic	anionic	ADJ
cuesj-1234	231	18	surfactants	surfactant	NOUN
cuesj-1234	231	19	.	.	PUNCT
cuesj-1234	232	1	oilfield	oilfield	NOUN
cuesj-1234	232	2	chemistry	chemistry	NOUN
cuesj-1234	232	3	,	,	PUNCT
cuesj-1234	232	4	vol	vol	NOUN
cuesj-1234	232	5	.	.	PROPN
cuesj-1234	233	1	34	34	NUM
cuesj-1234	233	2	,	,	PUNCT
cuesj-1234	233	3	pp	pp	ADJ
cuesj-1234	233	4	.	.	PUNCT
cuesj-1234	234	1	306	306	NUM
cuesj-1234	234	2	-	-	SYM
cuesj-1234	234	3	311	311	NUM
cuesj-1234	234	4	,	,	PUNCT
cuesj-1234	234	5	2017	2017	NUM
cuesj-1234	234	6	.	.	PUNCT
cuesj-1234	235	1	18	18	NUM
cuesj-1234	235	2	.	.	PUNCT
cuesj-1234	236	1	p.	p.	NOUN
cuesj-1234	236	2	held	hold	VERB
cuesj-1234	236	3	.	.	PUNCT
cuesj-1234	237	1	rapid	rapid	ADJ
cuesj-1234	237	2	critical	critical	ADJ
cuesj-1234	237	3	micelle	micelle	NOUN
cuesj-1234	237	4	concentration	concentration	NOUN
cuesj-1234	237	5	(	(	PUNCT
cuesj-1234	237	6	cmc	cmc	NOUN
cuesj-1234	237	7	)	)	PUNCT
cuesj-1234	237	8	determination	determination	NOUN
cuesj-1234	237	9	using	use	VERB
cuesj-1234	237	10	fluorescence	fluorescence	NOUN
cuesj-1234	237	11	polarization	polarization	NOUN
cuesj-1234	237	12	;	;	PUNCT
cuesj-1234	237	13	2021	2021	NUM
cuesj-1234	237	14	.	.	PUNCT
cuesj-1234	237	15	available	available	ADJ
cuesj-1234	237	16	from	from	ADP
cuesj-1234	237	17	:	:	PUNCT
cuesj-1234	237	18	https://	https://	PROPN
cuesj-1234	237	19	al	al	PROPN
cuesj-1234	237	20	-	-	PUNCT
cuesj-1234	237	21	jumaili	jumaili	PROPN
cuesj-1234	237	22	,	,	PUNCT
cuesj-1234	237	23	et	et	PROPN
cuesj-1234	237	24	al	al	PROPN
cuesj-1234	237	25	.	.	PROPN
cuesj-1234	237	26	:	:	PUNCT
cuesj-1234	237	27	enhancing	enhance	VERB
cuesj-1234	237	28	solubility	solubility	NOUN
cuesj-1234	237	29	of	of	ADP
cuesj-1234	237	30	simvastatin	simvastatin	NOUN
cuesj-1234	237	31	with	with	ADP
cuesj-1234	237	32	l	l	NOUN
cuesj-1234	237	33	-	-	NOUN
cuesj-1234	237	34	isoleucine	isoleucine	ADJ
cuesj-1234	237	35	and	and	CCONJ
cuesj-1234	237	36	sodium	sodium	NOUN
cuesj-1234	237	37	docusate	docusate	NOUN
cuesj-1234	237	38	32	32	NUM
cuesj-1234	237	39	http://journals.cihanuniversity.edu.iq/index.php/cuesj	http://journals.cihanuniversity.edu.iq/index.php/cuesj	ADJ
cuesj-1234	237	40	cuesj	cuesj	NOUN
cuesj-1234	237	41	2025	2025	NUM
cuesj-1234	237	42	,	,	PUNCT
cuesj-1234	237	43	9	9	NUM
cuesj-1234	237	44	(	(	PUNCT
cuesj-1234	237	45	2	2	NUM
cuesj-1234	237	46	):	):	PUNCT
cuesj-1234	237	47	26	26	NUM
cuesj-1234	237	48	-	-	SYM
cuesj-1234	237	49	32	32	NUM
cuesj-1234	237	50	www.biotek.com/resources/articles/cmc-determination-usingfluorescence-polarization.html	www.biotek.com/resources/articles/cmc-determination-usingfluorescence-polarization.html	VERB
cuesj-1234	238	1	[	[	X
cuesj-1234	238	2	last	last	ADV
cuesj-1234	238	3	accessed	access	VERB
cuesj-1234	238	4	on	on	ADP
cuesj-1234	238	5	2023	2023	NUM
cuesj-1234	238	6	mar	mar	PROPN
cuesj-1234	238	7	27	27	NUM
cuesj-1234	238	8	]	]	PUNCT
cuesj-1234	238	9	.	.	PUNCT
cuesj-1234	239	1	19	19	NUM
cuesj-1234	239	2	.	.	X
cuesj-1234	239	3	b.	b.	PROPN
cuesj-1234	239	4	shuang	shuang	PROPN
cuesj-1234	239	5	,	,	PUNCT
cuesj-1234	239	6	m.	m.	NOUN
cuesj-1234	239	7	xiaoqian	xiaoqian	PROPN
cuesj-1234	239	8	and	and	CCONJ
cuesj-1234	239	9	z.	z.	PROPN
cuesj-1234	239	10	tian	tian	PROPN
cuesj-1234	239	11	.	.	PUNCT
cuesj-1234	240	1	nano	nano	NOUN
cuesj-1234	240	2	-	-	PUNCT
cuesj-1234	240	3	engineered	engineer	VERB
cuesj-1234	240	4	biomaterials	biomaterial	NOUN
cuesj-1234	240	5	for	for	ADP
cuesj-1234	240	6	advanced	advanced	ADJ
cuesj-1234	240	7	drug	drug	NOUN
cuesj-1234	240	8	delivery	delivery	NOUN
cuesj-1234	240	9	.	.	PUNCT
cuesj-1234	241	1	elsevier	elsevier	PROPN
cuesj-1234	241	2	science	science	PROPN
cuesj-1234	241	3	,	,	PUNCT
cuesj-1234	241	4	netherlands	netherlands	PROPN
cuesj-1234	241	5	,	,	PUNCT
cuesj-1234	241	6	pp	pp	PROPN
cuesj-1234	241	7	.	.	PUNCT
cuesj-1234	242	1	261	261	NUM
cuesj-1234	242	2	-	-	NUM
cuesj-1234	242	3	278	278	NUM
cuesj-1234	242	4	,	,	PUNCT
cuesj-1234	242	5	2020	2020	NUM
cuesj-1234	242	6	.	.	PUNCT
cuesj-1234	243	1	20	20	NUM
cuesj-1234	243	2	.	.	PUNCT
cuesj-1234	244	1	docusate	docusate	NOUN
cuesj-1234	244	2	sodium	sodium	NOUN
cuesj-1234	244	3	(	(	PUNCT
cuesj-1234	244	4	dioctyl	dioctyl	NOUN
cuesj-1234	244	5	sulfosuccinate	sulfosuccinate	NOUN
cuesj-1234	244	6	sodium	sodium	NOUN
cuesj-1234	244	7	salt	salt	NOUN
cuesj-1234	244	8	)	)	PUNCT
cuesj-1234	244	9	hsv	hsv	NOUN
cuesj-1234	244	10	inhibitor	inhibitor	NOUN
cuesj-1234	244	11	med	med	ADJ
cuesj-1234	244	12	chem	chem	NOUN
cuesj-1234	244	13	express	express	NOUN
cuesj-1234	244	14	.	.	PUNCT
cuesj-1234	245	1	available	available	ADJ
cuesj-1234	245	2	from	from	ADP
cuesj-1234	245	3	:	:	PUNCT
cuesj-1234	245	4	https://www	https://www	PROPN
cuesj-1234	245	5	.	.	PUNCT
cuesj-1234	246	1	medchemexpress.com/docusate-sodium.html	medchemexpress.com/docusate-sodium.html	NOUN
cuesj-1234	246	2	[	[	X
cuesj-1234	246	3	last	last	ADV
cuesj-1234	246	4	accessed	access	VERB
cuesj-1234	246	5	on	on	ADP
cuesj-1234	246	6	2023	2023	NUM
cuesj-1234	246	7	mar	mar	PROPN
cuesj-1234	246	8	23	23	NUM
cuesj-1234	246	9	]	]	PUNCT
cuesj-1234	246	10	.	.	PUNCT
cuesj-1234	247	1	21	21	NUM
cuesj-1234	247	2	.	.	PUNCT
cuesj-1234	247	3	c.	c.	PROPN
cuesj-1234	247	4	gu	gu	PROPN
cuesj-1234	247	5	,	,	PUNCT
cuesj-1234	247	6	x.	x.	PROPN
cuesj-1234	247	7	mao	mao	PROPN
cuesj-1234	247	8	,	,	PUNCT
cuesj-1234	247	9	d.	d.	PROPN
cuesj-1234	247	10	chen	chen	PROPN
cuesj-1234	247	11	,	,	PUNCT
cuesj-1234	247	12	b.	b.	PROPN
cuesj-1234	247	13	yu	yu	PROPN
cuesj-1234	247	14	and	and	CCONJ
cuesj-1234	247	15	q.	q.	PROPN
cuesj-1234	247	16	yang	yang	PROPN
cuesj-1234	247	17	.	.	PUNCT
cuesj-1234	248	1	isoleucine	isoleucine	PROPN
cuesj-1234	248	2	plays	play	VERB
cuesj-1234	248	3	an	an	DET
cuesj-1234	248	4	important	important	ADJ
cuesj-1234	248	5	role	role	NOUN
cuesj-1234	248	6	for	for	ADP
cuesj-1234	248	7	maintaining	maintain	VERB
cuesj-1234	248	8	immune	immune	ADJ
cuesj-1234	248	9	function	function	NOUN
cuesj-1234	248	10	.	.	PUNCT
cuesj-1234	249	1	current	current	ADJ
cuesj-1234	249	2	protein	protein	NOUN
cuesj-1234	249	3	peptide	peptide	NOUN
cuesj-1234	249	4	science	science	NOUN
cuesj-1234	249	5	,	,	PUNCT
cuesj-1234	249	6	vol	vol	NOUN
cuesj-1234	249	7	.	.	PROPN
cuesj-1234	249	8	20	20	NUM
cuesj-1234	249	9	,	,	PUNCT
cuesj-1234	249	10	no	no	INTJ
cuesj-1234	249	11	.	.	NOUN
cuesj-1234	249	12	7	7	NUM
cuesj-1234	249	13	,	,	PUNCT
cuesj-1234	249	14	pp	pp	ADJ
cuesj-1234	249	15	.	.	PUNCT
cuesj-1234	250	1	644	644	NUM
cuesj-1234	250	2	-	-	SYM
cuesj-1234	250	3	651	651	NUM
cuesj-1234	250	4	,	,	PUNCT
cuesj-1234	250	5	2019	2019	NUM
cuesj-1234	250	6	.	.	PUNCT
cuesj-1234	251	1	22	22	NUM
cuesj-1234	251	2	.	.	PUNCT
cuesj-1234	251	3	d.	d.	PROPN
cuesj-1234	251	4	a.	a.	PROPN
cuesj-1234	251	5	bender	bender	PROPN
cuesj-1234	251	6	.	.	PUNCT
cuesj-1234	252	1	the	the	DET
cuesj-1234	252	2	branched	branch	VERB
cuesj-1234	252	3	-	-	PUNCT
cuesj-1234	252	4	chain	chain	NOUN
cuesj-1234	252	5	amino	amino	NOUN
cuesj-1234	252	6	acids	acid	NOUN
cuesj-1234	252	7	:	:	PUNCT
cuesj-1234	252	8	leucine	leucine	NOUN
cuesj-1234	252	9	,	,	PUNCT
cuesj-1234	252	10	isoleucine	isoleucine	NOUN
cuesj-1234	252	11	and	and	CCONJ
cuesj-1234	252	12	valine	valine	NOUN
cuesj-1234	252	13	.	.	PUNCT
cuesj-1234	253	1	in	in	ADP
cuesj-1234	253	2	:	:	PUNCT
cuesj-1234	253	3	amino	amino	NOUN
cuesj-1234	253	4	acid	acid	NOUN
cuesj-1234	253	5	metabolism	metabolism	NOUN
cuesj-1234	253	6	.	.	PUNCT
cuesj-1234	254	1	john	john	PROPN
cuesj-1234	254	2	wiley	wiley	PROPN
cuesj-1234	254	3	and	and	CCONJ
cuesj-1234	254	4	sons	son	NOUN
cuesj-1234	254	5	,	,	PUNCT
cuesj-1234	254	6	ltd	ltd	PROPN
cuesj-1234	254	7	.	.	PROPN
cuesj-1234	254	8	,	,	PUNCT
cuesj-1234	254	9	united	united	PROPN
cuesj-1234	254	10	states	states	PROPN
cuesj-1234	254	11	,	,	PUNCT
cuesj-1234	254	12	pp	pp	ADV
cuesj-1234	254	13	.	.	PUNCT
cuesj-1234	255	1	279	279	NUM
cuesj-1234	255	2	-	-	SYM
cuesj-1234	255	3	303	303	NUM
cuesj-1234	255	4	,	,	PUNCT
cuesj-1234	255	5	2012	2012	NUM
cuesj-1234	255	6	.	.	PUNCT
cuesj-1234	256	1	23	23	NUM
cuesj-1234	256	2	.	.	PUNCT
cuesj-1234	256	3	m.	m.	PROPN
cuesj-1234	256	4	j.	j.	PROPN
cuesj-1234	256	5	o’neil	o’neil	PROPN
cuesj-1234	256	6	.	.	PUNCT
cuesj-1234	257	1	isoleucine	isoleucine	PROPN
cuesj-1234	257	2	.	.	PUNCT
cuesj-1234	258	1	in	in	ADP
cuesj-1234	258	2	:	:	PUNCT
cuesj-1234	258	3	the	the	DET
cuesj-1234	258	4	merck	merck	PROPN
cuesj-1234	258	5	index	index	NOUN
cuesj-1234	258	6	an	an	DET
cuesj-1234	258	7	encyclopedia	encyclopedia	NOUN
cuesj-1234	258	8	of	of	ADP
cuesj-1234	258	9	chemicals	chemical	NOUN
cuesj-1234	258	10	,	,	PUNCT
cuesj-1234	258	11	drugs	drug	NOUN
cuesj-1234	258	12	,	,	PUNCT
cuesj-1234	258	13	and	and	CCONJ
cuesj-1234	258	14	biological	biological	ADJ
cuesj-1234	258	15	.	.	PUNCT
cuesj-1234	259	1	royal	royal	ADJ
cuesj-1234	259	2	society	society	NOUN
cuesj-1234	259	3	of	of	ADP
cuesj-1234	259	4	chemistry	chemistry	NOUN
cuesj-1234	259	5	,	,	PUNCT
cuesj-1234	259	6	uk	uk	PROPN
cuesj-1234	259	7	,	,	PUNCT
cuesj-1234	259	8	p.	p.	NOUN
cuesj-1234	259	9	896	896	NUM
cuesj-1234	259	10	,	,	PUNCT
cuesj-1234	259	11	2013	2013	NUM
cuesj-1234	259	12	.	.	PUNCT
cuesj-1234	260	1	24	24	NUM
cuesj-1234	260	2	.	.	PUNCT
cuesj-1234	260	3	m.	m.	NOUN
cuesj-1234	260	4	m.	m.	PROPN
cuesj-1234	260	5	m.	m.	PROPN
cuesj-1234	260	6	affandi	affandi	PROPN
cuesj-1234	260	7	,	,	PUNCT
cuesj-1234	260	8	m.	m.	NOUN
cuesj-1234	260	9	tripathy	tripathy	PROPN
cuesj-1234	260	10	,	,	PUNCT
cuesj-1234	260	11	a.	a.	NOUN
cuesj-1234	260	12	shah	shah	NOUN
cuesj-1234	260	13	and	and	CCONJ
cuesj-1234	260	14	a.	a.	PROPN
cuesj-1234	260	15	a.	a.	PROPN
cuesj-1234	260	16	b.	b.	PROPN
cuesj-1234	260	17	majeed	majeed	PROPN
cuesj-1234	260	18	.	.	PUNCT
cuesj-1234	261	1	solubility	solubility	NOUN
cuesj-1234	261	2	enhancement	enhancement	NOUN
cuesj-1234	261	3	of	of	ADP
cuesj-1234	261	4	simvastatin	simvastatin	NOUN
cuesj-1234	261	5	by	by	ADP
cuesj-1234	261	6	arginine	arginine	NOUN
cuesj-1234	261	7	:	:	PUNCT
cuesj-1234	261	8	thermodynamics	thermodynamic	NOUN
cuesj-1234	261	9	,	,	PUNCT
cuesj-1234	261	10	solute	solute	ADJ
cuesj-1234	261	11	-	-	PUNCT
cuesj-1234	261	12	solvent	solvent	ADJ
cuesj-1234	261	13	interactions	interaction	NOUN
cuesj-1234	261	14	,	,	PUNCT
cuesj-1234	261	15	and	and	CCONJ
cuesj-1234	261	16	spectral	spectral	ADJ
cuesj-1234	261	17	analysis	analysis	NOUN
cuesj-1234	261	18	.	.	PUNCT
cuesj-1234	262	1	drug	drug	NOUN
cuesj-1234	262	2	design	design	PROPN
cuesj-1234	262	3	development	development	NOUN
cuesj-1234	262	4	therapy	therapy	NOUN
cuesj-1234	262	5	,	,	PUNCT
cuesj-1234	262	6	vol	vol	NOUN
cuesj-1234	262	7	.	.	PROPN
cuesj-1234	263	1	10	10	NUM
cuesj-1234	263	2	,	,	PUNCT
cuesj-1234	263	3	pp	pp	ADJ
cuesj-1234	263	4	.	.	PUNCT
cuesj-1234	264	1	959	959	NUM
cuesj-1234	264	2	-	-	SYM
cuesj-1234	264	3	969	969	NUM
cuesj-1234	264	4	,	,	PUNCT
cuesj-1234	264	5	2016	2016	NUM
cuesj-1234	264	6	.	.	PUNCT
cuesj-1234	265	1	25	25	NUM
cuesj-1234	265	2	.	.	PUNCT
cuesj-1234	266	1	h.	h.	PROPN
cuesj-1234	266	2	a.	a.	PROPN
cuesj-1234	266	3	hamadameen	hamadameen	PROPN
cuesj-1234	266	4	,	,	PUNCT
cuesj-1234	266	5	h.	h.	PROPN
cuesj-1234	266	6	l.	l.	PROPN
cuesj-1234	266	7	qader	qader	PROPN
cuesj-1234	266	8	and	and	CCONJ
cuesj-1234	266	9	a.	a.	PROPN
cuesj-1234	266	10	h.	h.	PROPN
cuesj-1234	266	11	abdullah	abdullah	PROPN
cuesj-1234	266	12	.	.	PUNCT
cuesj-1234	267	1	improvement	improvement	NOUN
cuesj-1234	267	2	of	of	ADP
cuesj-1234	267	3	solubility	solubility	NOUN
cuesj-1234	267	4	and	and	CCONJ
cuesj-1234	267	5	dissolution	dissolution	NOUN
cuesj-1234	267	6	rate	rate	NOUN
cuesj-1234	267	7	of	of	ADP
cuesj-1234	267	8	biopharmaceutical	biopharmaceutical	PROPN
cuesj-1234	267	9	class	class	PROPN
cuesj-1234	267	10	ii	ii	PROPN
cuesj-1234	267	11	drug	drug	NOUN
cuesj-1234	267	12	atorvastatin	atorvastatin	NOUN
cuesj-1234	267	13	calcium	calcium	NOUN
cuesj-1234	267	14	by	by	ADP
cuesj-1234	267	15	using	use	VERB
cuesj-1234	267	16	an	an	DET
cuesj-1234	267	17	essential	essential	ADJ
cuesj-1234	267	18	amino	amino	NOUN
cuesj-1234	267	19	acid	acid	NOUN
cuesj-1234	267	20	l	l	PROPN
cuesj-1234	267	21	-	-	NOUN
cuesj-1234	267	22	leucine	leucine	NOUN
cuesj-1234	267	23	.	.	PUNCT
cuesj-1234	268	1	zanco	zanco	PROPN
cuesj-1234	268	2	journal	journal	PROPN
cuesj-1234	268	3	medical	medical	ADJ
cuesj-1234	268	4	science	science	PROPN
cuesj-1234	268	5	,	,	PUNCT
cuesj-1234	268	6	vol	vol	NOUN
cuesj-1234	268	7	.	.	PROPN
cuesj-1234	268	8	26	26	NUM
cuesj-1234	268	9	,	,	PUNCT
cuesj-1234	268	10	no	no	INTJ
cuesj-1234	268	11	.	.	NOUN
cuesj-1234	268	12	1	1	NUM
cuesj-1234	268	13	,	,	PUNCT
cuesj-1234	268	14	pp	pp	ADJ
cuesj-1234	268	15	.	.	PUNCT
cuesj-1234	269	1	67	67	NUM
cuesj-1234	269	2	-	-	SYM
cuesj-1234	269	3	77	77	NUM
cuesj-1234	269	4	,	,	PUNCT
cuesj-1234	269	5	2022	2022	NUM
cuesj-1234	269	6	.	.	PUNCT
cuesj-1234	270	1	26	26	NUM
cuesj-1234	270	2	.	.	PUNCT
cuesj-1234	270	3	a.	a.	PROPN
cuesj-1234	270	4	m.	m.	PROPN
cuesj-1234	270	5	helmenstine	helmenstine	PROPN
cuesj-1234	270	6	.	.	PUNCT
cuesj-1234	271	1	amino	amino	PROPN
cuesj-1234	271	2	acid	acid	NOUN
cuesj-1234	271	3	structures	structure	NOUN
cuesj-1234	271	4	.	.	PUNCT
cuesj-1234	272	1	thoughtco	thoughtco	PROPN
cuesj-1234	272	2	.	.	PUNCT
cuesj-1234	273	1	available	available	ADJ
cuesj-1234	273	2	from	from	ADP
cuesj-1234	273	3	:	:	PUNCT
cuesj-1234	273	4	https://www.thoughtco.com/amino-acidstructures-4054180	https://www.thoughtco.com/amino-acidstructures-4054180	PROPN
cuesj-1234	274	1	[	[	X
cuesj-1234	274	2	last	last	ADV
cuesj-1234	274	3	accessed	access	VERB
cuesj-1234	274	4	on	on	ADP
cuesj-1234	274	5	2023	2023	NUM
cuesj-1234	274	6	mar	mar	PROPN
cuesj-1234	274	7	23	23	NUM
cuesj-1234	274	8	]	]	PUNCT
cuesj-1234	274	9	.	.	PUNCT
cuesj-1234	275	1	27	27	NUM
cuesj-1234	275	2	.	.	PUNCT
cuesj-1234	276	1	p.	p.	NOUN
cuesj-1234	276	2	tran	tran	PROPN
cuesj-1234	276	3	,	,	PUNCT
cuesj-1234	276	4	y.	y.	PROPN
cuesj-1234	276	5	c.	c.	PROPN
cuesj-1234	276	6	pyo	pyo	PROPN
cuesj-1234	276	7	,	,	PUNCT
cuesj-1234	276	8	d.	d.	PROPN
cuesj-1234	276	9	h.	h.	PROPN
cuesj-1234	276	10	kim	kim	PROPN
cuesj-1234	276	11	,	,	PUNCT
cuesj-1234	276	12	s.	s.	PROPN
cuesj-1234	276	13	e.	e.	PROPN
cuesj-1234	276	14	lee	lee	PROPN
cuesj-1234	276	15	,	,	PUNCT
cuesj-1234	276	16	j.	j.	PROPN
cuesj-1234	276	17	k.	k.	PROPN
cuesj-1234	276	18	kim	kim	PROPN
cuesj-1234	276	19	and	and	CCONJ
cuesj-1234	276	20	j.	j.	PROPN
cuesj-1234	276	21	s.	s.	PROPN
cuesj-1234	276	22	park	park	PROPN
cuesj-1234	276	23	.	.	PUNCT
cuesj-1234	277	1	overview	overview	NOUN
cuesj-1234	277	2	of	of	ADP
cuesj-1234	277	3	the	the	DET
cuesj-1234	277	4	manufacturing	manufacture	VERB
cuesj-1234	277	5	methods	method	NOUN
cuesj-1234	277	6	of	of	ADP
cuesj-1234	277	7	solid	solid	ADJ
cuesj-1234	277	8	dispersion	dispersion	NOUN
cuesj-1234	277	9	technology	technology	NOUN
cuesj-1234	277	10	for	for	ADP
cuesj-1234	277	11	improving	improve	VERB
cuesj-1234	277	12	the	the	DET
cuesj-1234	277	13	solubility	solubility	NOUN
cuesj-1234	277	14	of	of	ADP
cuesj-1234	277	15	poorly	poorly	ADV
cuesj-1234	277	16	water	water	NOUN
cuesj-1234	277	17	-	-	PUNCT
cuesj-1234	277	18	soluble	soluble	ADJ
cuesj-1234	277	19	drugs	drug	NOUN
cuesj-1234	277	20	and	and	CCONJ
cuesj-1234	277	21	application	application	NOUN
cuesj-1234	277	22	to	to	PART
cuesj-1234	277	23	anticancer	anticancer	NOUN
cuesj-1234	277	24	drugs	drug	NOUN
cuesj-1234	277	25	.	.	PUNCT
cuesj-1234	278	1	pharmaceutics	pharmaceutic	NOUN
cuesj-1234	278	2	,	,	PUNCT
cuesj-1234	278	3	vol	vol	NOUN
cuesj-1234	278	4	.	.	PROPN
cuesj-1234	278	5	11	11	NUM
cuesj-1234	278	6	,	,	PUNCT
cuesj-1234	278	7	no	no	INTJ
cuesj-1234	278	8	.	.	NOUN
cuesj-1234	278	9	3	3	NUM
cuesj-1234	278	10	,	,	PUNCT
cuesj-1234	278	11	p.	p.	NOUN
cuesj-1234	278	12	132	132	NUM
cuesj-1234	278	13	,	,	PUNCT
cuesj-1234	278	14	2019	2019	NUM
cuesj-1234	278	15	.	.	PUNCT
cuesj-1234	279	1	28	28	NUM
cuesj-1234	279	2	.	.	PUNCT
cuesj-1234	280	1	c.	c.	PROPN
cuesj-1234	280	2	l.	l.	PROPN
cuesj-1234	280	3	n.	n.	PROPN
cuesj-1234	280	4	vo	vo	PROPN
cuesj-1234	280	5	,	,	PUNCT
cuesj-1234	280	6	c.	c.	PROPN
cuesj-1234	280	7	park	park	PROPN
cuesj-1234	280	8	and	and	CCONJ
cuesj-1234	280	9	b.	b.	PROPN
cuesj-1234	280	10	j.	j.	PROPN
cuesj-1234	280	11	lee	lee	PROPN
cuesj-1234	280	12	.	.	PUNCT
cuesj-1234	281	1	current	current	ADJ
cuesj-1234	281	2	trends	trend	NOUN
cuesj-1234	281	3	and	and	CCONJ
cuesj-1234	281	4	future	future	ADJ
cuesj-1234	281	5	perspectives	perspective	NOUN
cuesj-1234	281	6	of	of	ADP
cuesj-1234	281	7	solid	solid	ADJ
cuesj-1234	281	8	dispersions	dispersion	NOUN
cuesj-1234	281	9	containing	contain	VERB
cuesj-1234	281	10	poorly	poorly	ADV
cuesj-1234	281	11	water	water	NOUN
cuesj-1234	281	12	-	-	PUNCT
cuesj-1234	281	13	soluble	soluble	ADJ
cuesj-1234	281	14	drugs	drug	NOUN
cuesj-1234	281	15	.	.	PUNCT
cuesj-1234	282	1	european	european	PROPN
cuesj-1234	282	2	journal	journal	PROPN
cuesj-1234	282	3	pharmaceutics	pharmaceutic	NOUN
cuesj-1234	282	4	biopharmaceutics	biopharmaceutics	PROPN
cuesj-1234	282	5	,	,	PUNCT
cuesj-1234	282	6	vol	vol	NOUN
cuesj-1234	282	7	.	.	PROPN
cuesj-1234	282	8	85	85	NUM
cuesj-1234	282	9	,	,	PUNCT
cuesj-1234	282	10	no	no	INTJ
cuesj-1234	282	11	.	.	NOUN
cuesj-1234	282	12	3	3	NUM
cuesj-1234	282	13	pt	pt	PROPN
cuesj-1234	282	14	b	b	NOUN
cuesj-1234	282	15	,	,	PUNCT
cuesj-1234	282	16	pp	pp	PROPN
cuesj-1234	282	17	.	.	PUNCT
cuesj-1234	283	1	799	799	NUM
cuesj-1234	283	2	-	-	SYM
cuesj-1234	283	3	813	813	NUM
cuesj-1234	283	4	,	,	PUNCT
cuesj-1234	283	5	2013	2013	NUM
cuesj-1234	283	6	.	.	PUNCT
cuesj-1234	284	1	29	29	NUM
cuesj-1234	284	2	.	.	PUNCT
cuesj-1234	285	1	t.	t.	PROPN
cuesj-1234	285	2	vasconcelos	vasconcelos	PROPN
cuesj-1234	285	3	,	,	PUNCT
cuesj-1234	285	4	b.	b.	PROPN
cuesj-1234	285	5	sarmento	sarmento	PROPN
cuesj-1234	285	6	and	and	CCONJ
cuesj-1234	285	7	p.	p.	PROPN
cuesj-1234	285	8	costa	costa	PROPN
cuesj-1234	285	9	.	.	PUNCT
cuesj-1234	286	1	solid	solid	ADJ
cuesj-1234	286	2	dispersions	dispersion	NOUN
cuesj-1234	286	3	as	as	ADP
cuesj-1234	286	4	strategy	strategy	NOUN
cuesj-1234	286	5	to	to	PART
cuesj-1234	286	6	improve	improve	VERB
cuesj-1234	286	7	oral	oral	ADJ
cuesj-1234	286	8	bioavailability	bioavailability	NOUN
cuesj-1234	286	9	of	of	ADP
cuesj-1234	286	10	poor	poor	ADJ
cuesj-1234	286	11	water	water	NOUN
cuesj-1234	286	12	soluble	soluble	ADJ
cuesj-1234	286	13	drugs	drug	NOUN
cuesj-1234	286	14	.	.	PUNCT
cuesj-1234	287	1	drug	drug	NOUN
cuesj-1234	287	2	discovery	discovery	PROPN
cuesj-1234	287	3	today	today	NOUN
cuesj-1234	287	4	,	,	PUNCT
cuesj-1234	287	5	vol	vol	NOUN
cuesj-1234	287	6	.	.	PROPN
cuesj-1234	288	1	12	12	NUM
cuesj-1234	288	2	,	,	PUNCT
cuesj-1234	288	3	no	no	INTJ
cuesj-1234	288	4	.	.	NOUN
cuesj-1234	288	5	23	23	NUM
cuesj-1234	288	6	-	-	SYM
cuesj-1234	288	7	24	24	NUM
cuesj-1234	288	8	,	,	PUNCT
cuesj-1234	288	9	pp	pp	ADJ
cuesj-1234	288	10	.	.	PUNCT
cuesj-1234	289	1	1068	1068	NUM
cuesj-1234	289	2	-	-	SYM
cuesj-1234	289	3	1075	1075	NUM
cuesj-1234	289	4	,	,	PUNCT
cuesj-1234	289	5	2007	2007	NUM
cuesj-1234	289	6	.	.	PUNCT
cuesj-1234	290	1	30	30	NUM
cuesj-1234	290	2	.	.	PUNCT
cuesj-1234	291	1	k.	k.	PROPN
cuesj-1234	291	2	t.	t.	PROPN
cuesj-1234	291	3	savjani	savjani	PROPN
cuesj-1234	291	4	,	,	PUNCT
cuesj-1234	291	5	a.	a.	PROPN
cuesj-1234	291	6	k.	k.	PROPN
cuesj-1234	291	7	gajjar	gajjar	PROPN
cuesj-1234	291	8	and	and	CCONJ
cuesj-1234	291	9	j.	j.	PROPN
cuesj-1234	291	10	k.	k.	PROPN
cuesj-1234	291	11	savjani	savjani	PROPN
cuesj-1234	291	12	.	.	PUNCT
cuesj-1234	292	1	drug	drug	NOUN
cuesj-1234	292	2	solubility	solubility	NOUN
cuesj-1234	292	3	:	:	PUNCT
cuesj-1234	292	4	importance	importance	NOUN
cuesj-1234	292	5	and	and	CCONJ
cuesj-1234	292	6	enhancement	enhancement	NOUN
cuesj-1234	292	7	techniques	technique	NOUN
cuesj-1234	292	8	.	.	PUNCT
cuesj-1234	293	1	isrn	isrn	PROPN
cuesj-1234	293	2	pharmacology	pharmacology	PROPN
cuesj-1234	293	3	,	,	PUNCT
cuesj-1234	293	4	vol	vol	NOUN
cuesj-1234	293	5	.	.	PROPN
cuesj-1234	293	6	2012	2012	NUM
cuesj-1234	293	7	,	,	PUNCT
cuesj-1234	293	8	p.	p.	NOUN
cuesj-1234	293	9	195727	195727	NUM
cuesj-1234	293	10	,	,	PUNCT
cuesj-1234	293	11	2012	2012	NUM
cuesj-1234	293	12	.	.	PUNCT
cuesj-1234	294	1	31	31	NUM
cuesj-1234	294	2	.	.	PUNCT
cuesj-1234	294	3	r.	r.	PROPN
cuesj-1234	294	4	m.	m.	PROPN
cuesj-1234	294	5	elkanayati	elkanayati	PROPN
cuesj-1234	294	6	,	,	PUNCT
cuesj-1234	294	7	i.	i.	PROPN
cuesj-1234	294	8	karnik	karnik	PROPN
cuesj-1234	294	9	,	,	PUNCT
cuesj-1234	294	10	p.	p.	PROPN
cuesj-1234	294	11	uttreja	uttreja	PROPN
cuesj-1234	294	12	,	,	PUNCT
cuesj-1234	294	13	n.	n.	NOUN
cuesj-1234	294	14	narala	narala	PROPN
cuesj-1234	294	15	,	,	PUNCT
cuesj-1234	294	16	s.	s.	PROPN
cuesj-1234	294	17	k.	k.	PROPN
cuesj-1234	294	18	vemula	vemula	PROPN
cuesj-1234	294	19	,	,	PUNCT
cuesj-1234	294	20	k.	k.	PROPN
cuesj-1234	294	21	karry	karry	PROPN
cuesj-1234	294	22	and	and	CCONJ
cuesj-1234	294	23	m.	m.	NOUN
cuesj-1234	294	24	a.	a.	NOUN
cuesj-1234	294	25	repka	repka	PROPN
cuesj-1234	294	26	.	.	PUNCT
cuesj-1234	295	1	twin	twin	PROPN
cuesj-1234	295	2	screw	screw	NOUN
cuesj-1234	295	3	melt	melt	VERB
cuesj-1234	295	4	granulation	granulation	NOUN
cuesj-1234	295	5	of	of	ADP
cuesj-1234	295	6	simvastatin	simvastatin	NOUN
cuesj-1234	295	7	:	:	PUNCT
cuesj-1234	295	8	drug	drug	NOUN
cuesj-1234	295	9	solubility	solubility	NOUN
cuesj-1234	295	10	and	and	CCONJ
cuesj-1234	295	11	dissolution	dissolution	NOUN
cuesj-1234	295	12	rate	rate	NOUN
cuesj-1234	295	13	enhancement	enhancement	NOUN
cuesj-1234	295	14	using	use	VERB
cuesj-1234	295	15	polymer	polymer	NOUN
cuesj-1234	295	16	blends	blend	NOUN
cuesj-1234	295	17	.	.	PUNCT
cuesj-1234	296	1	pharmaceutics	pharmaceutic	NOUN
cuesj-1234	296	2	,	,	PUNCT
cuesj-1234	296	3	vol	vol	NOUN
cuesj-1234	296	4	.	.	PROPN
cuesj-1234	296	5	16	16	NUM
cuesj-1234	296	6	,	,	PUNCT
cuesj-1234	296	7	no	no	INTJ
cuesj-1234	296	8	.	.	NOUN
cuesj-1234	296	9	12	12	NUM
cuesj-1234	296	10	,	,	PUNCT
cuesj-1234	296	11	p.	p.	NOUN
cuesj-1234	296	12	1630	1630	NUM
cuesj-1234	296	13	,	,	PUNCT
cuesj-1234	296	14	2024	2024	NUM
cuesj-1234	296	15	.	.	PUNCT
cuesj-1234	297	1	32	32	NUM
cuesj-1234	297	2	.	.	PUNCT
cuesj-1234	298	1	f.	f.	PROPN
cuesj-1234	298	2	m.	m.	PROPN
cuesj-1234	298	3	khan	khan	PROPN
cuesj-1234	298	4	,	,	PUNCT
cuesj-1234	298	5	m.	m.	NOUN
cuesj-1234	298	6	ahmad	ahmad	PROPN
cuesj-1234	298	7	and	and	CCONJ
cuesj-1234	298	8	f.	f.	PROPN
cuesj-1234	298	9	batool	batool	PROPN
cuesj-1234	298	10	.	.	PUNCT
cuesj-1234	299	1	enhancement	enhancement	NOUN
cuesj-1234	299	2	of	of	ADP
cuesj-1234	299	3	solubility	solubility	NOUN
cuesj-1234	299	4	and	and	CCONJ
cuesj-1234	299	5	release	release	VERB
cuesj-1234	299	6	profile	profile	NOUN
cuesj-1234	299	7	of	of	ADP
cuesj-1234	299	8	simvastatin	simvastatin	NOUN
cuesj-1234	299	9	by	by	ADP
cuesj-1234	299	10	co	co	NOUN
cuesj-1234	299	11	-	-	NOUN
cuesj-1234	299	12	crystallization	crystallization	NOUN
cuesj-1234	299	13	with	with	ADP
cuesj-1234	299	14	citric	citric	ADJ
cuesj-1234	299	15	acid	acid	NOUN
cuesj-1234	299	16	.	.	PUNCT
cuesj-1234	300	1	tropical	tropical	ADJ
cuesj-1234	300	2	journal	journal	PROPN
cuesj-1234	300	3	pharmaceutical	pharmaceutical	PROPN
cuesj-1234	300	4	research	research	PROPN
cuesj-1234	300	5	,	,	PUNCT
cuesj-1234	300	6	vol	vol	NOUN
cuesj-1234	300	7	.	.	PROPN
cuesj-1234	300	8	18	18	NUM
cuesj-1234	300	9	,	,	PUNCT
cuesj-1234	300	10	no	no	INTJ
cuesj-1234	300	11	.	.	NOUN
cuesj-1234	300	12	12	12	NUM
cuesj-1234	300	13	,	,	PUNCT
cuesj-1234	300	14	pp	pp	ADJ
cuesj-1234	300	15	.	.	PUNCT
cuesj-1234	301	1	2465	2465	NUM
cuesj-1234	301	2	-	-	SYM
cuesj-1234	301	3	2472	2472	NUM
cuesj-1234	301	4	,	,	PUNCT
cuesj-1234	301	5	2019	2019	NUM
cuesj-1234	301	6	.	.	PUNCT
cuesj-1234	302	1	33	33	NUM
cuesj-1234	302	2	.	.	PUNCT
cuesj-1234	302	3	m.	m.	NOUN
cuesj-1234	302	4	a.	a.	PROPN
cuesj-1234	302	5	hashem	hashem	PROPN
cuesj-1234	302	6	,	,	PUNCT
cuesj-1234	302	7	a.	a.	PROPN
cuesj-1234	302	8	k.	k.	PROPN
cuesj-1234	302	9	hussein	hussein	PROPN
cuesj-1234	302	10	,	,	PUNCT
cuesj-1234	302	11	h.	h.	PROPN
cuesj-1234	302	12	abdelkader	abdelkader	PROPN
cuesj-1234	302	13	and	and	CCONJ
cuesj-1234	302	14	m.	m.	PROPN
cuesj-1234	302	15	s.	s.	PROPN
cuesj-1234	302	16	saddik	saddik	PROPN
cuesj-1234	302	17	.	.	PUNCT
cuesj-1234	303	1	solubility	solubility	NOUN
cuesj-1234	303	2	enhancement	enhancement	NOUN
cuesj-1234	303	3	of	of	ADP
cuesj-1234	303	4	simvastatin	simvastatin	NOUN
cuesj-1234	303	5	for	for	ADP
cuesj-1234	303	6	wound	wound	NOUN
cuesj-1234	303	7	dressing	dressing	NOUN
cuesj-1234	303	8	preparation	preparation	NOUN
cuesj-1234	303	9	.	.	PUNCT
cuesj-1234	304	1	journal	journal	PROPN
cuesj-1234	304	2	advanced	advanced	ADJ
cuesj-1234	304	3	biomedical	biomedical	ADJ
cuesj-1234	304	4	pharmaceutical	pharmaceutical	NOUN
cuesj-1234	304	5	science	science	NOUN
cuesj-1234	304	6	,	,	PUNCT
cuesj-1234	304	7	vol	vol	NOUN
cuesj-1234	304	8	.	.	PROPN
cuesj-1234	304	9	7	7	NUM
cuesj-1234	304	10	,	,	PUNCT
cuesj-1234	304	11	no	no	INTJ
cuesj-1234	304	12	.	.	NOUN
cuesj-1234	304	13	2	2	NUM
cuesj-1234	304	14	,	,	PUNCT
cuesj-1234	304	15	pp	pp	ADJ
cuesj-1234	304	16	.	.	PUNCT
cuesj-1234	305	1	75	75	NUM
cuesj-1234	305	2	-	-	SYM
cuesj-1234	305	3	79	79	NUM
cuesj-1234	305	4	,	,	PUNCT
cuesj-1234	305	5	2024	2024	NUM
cuesj-1234	305	6	.	.	PUNCT
cuesj-1234	306	1	34	34	NUM
cuesj-1234	306	2	.	.	PUNCT
cuesj-1234	307	1	v.	v.	ADP
cuesj-1234	307	2	parikh	parikh	PROPN
cuesj-1234	307	3	,	,	PUNCT
cuesj-1234	307	4	s.	s.	PROPN
cuesj-1234	307	5	g.	g.	PROPN
cuesj-1234	307	6	gumaste	gumaste	PROPN
cuesj-1234	307	7	and	and	CCONJ
cuesj-1234	307	8	s.	s.	PROPN
cuesj-1234	307	9	phadke	phadke	PROPN
cuesj-1234	307	10	.	.	PUNCT
cuesj-1234	308	1	effect	effect	NOUN
cuesj-1234	308	2	of	of	ADP
cuesj-1234	308	3	the	the	DET
cuesj-1234	308	4	interaction	interaction	NOUN
cuesj-1234	308	5	between	between	ADP
cuesj-1234	308	6	an	an	DET
cuesj-1234	308	7	ionic	ionic	ADJ
cuesj-1234	308	8	surfactant	surfactant	NOUN
cuesj-1234	308	9	and	and	CCONJ
cuesj-1234	308	10	polymer	polymer	NOUN
cuesj-1234	308	11	on	on	ADP
cuesj-1234	308	12	the	the	DET
cuesj-1234	308	13	dissolution	dissolution	NOUN
cuesj-1234	308	14	of	of	ADP
cuesj-1234	308	15	a	a	DET
cuesj-1234	308	16	poorly	poorly	ADV
cuesj-1234	308	17	soluble	soluble	ADJ
cuesj-1234	308	18	drug	drug	NOUN
cuesj-1234	308	19	.	.	PUNCT
cuesj-1234	309	1	aaps	aap	NOUN
cuesj-1234	309	2	pharmscitech	pharmscitech	VERB
cuesj-1234	309	3	,	,	PUNCT
cuesj-1234	309	4	vol	vol	NOUN
cuesj-1234	309	5	.	.	PROPN
cuesj-1234	310	1	19	19	NUM
cuesj-1234	310	2	,	,	PUNCT
cuesj-1234	310	3	no	no	INTJ
cuesj-1234	310	4	.	.	NOUN
cuesj-1234	310	5	7	7	NUM
cuesj-1234	310	6	,	,	PUNCT
cuesj-1234	310	7	pp	pp	ADJ
cuesj-1234	310	8	.	.	PUNCT
cuesj-1234	311	1	30403047	30403047	NUM
cuesj-1234	311	2	,	,	PUNCT
cuesj-1234	311	3	2018	2018	NUM
cuesj-1234	311	4	.	.	PUNCT
cuesj-1234	312	1	35	35	NUM
cuesj-1234	312	2	.	.	PUNCT
cuesj-1234	312	3	n.	n.	PROPN
cuesj-1234	312	4	s.	s.	PROPN
cuesj-1234	312	5	m.	m.	PROPN
cuesj-1234	312	6	azmi	azmi	PROPN
cuesj-1234	312	7	,	,	PUNCT
cuesj-1234	312	8	n.	n.	PROPN
cuesj-1234	312	9	anuar	anuar	PROPN
cuesj-1234	312	10	,	,	PUNCT
cuesj-1234	312	11	k.	k.	PROPN
cuesj-1234	312	12	j.	j.	PROPN
cuesj-1234	312	13	roberts	roberts	PROPN
cuesj-1234	312	14	,	,	PUNCT
cuesj-1234	312	15	n.	n.	PROPN
cuesj-1234	312	16	f.	f.	PROPN
cuesj-1234	312	17	abu	abu	PROPN
cuesj-1234	312	18	bakar	bakar	PROPN
cuesj-1234	312	19	and	and	CCONJ
cuesj-1234	312	20	n.	n.	PROPN
cuesj-1234	312	21	f.	f.	PROPN
cuesj-1234	312	22	kamalul	kamalul	PROPN
cuesj-1234	312	23	aripin	aripin	PROPN
cuesj-1234	312	24	.	.	PUNCT
cuesj-1234	313	1	molecular	molecular	ADJ
cuesj-1234	313	2	aggregation	aggregation	NOUN
cuesj-1234	313	3	of	of	ADP
cuesj-1234	313	4	l	l	NOUN
cuesj-1234	313	5	-	-	NOUN
cuesj-1234	313	6	isoleucine	isoleucine	NOUN
cuesj-1234	313	7	in	in	ADP
cuesj-1234	313	8	aqueous	aqueous	ADJ
cuesj-1234	313	9	solution	solution	NOUN
cuesj-1234	313	10	and	and	CCONJ
cuesj-1234	313	11	its	its	PRON
cuesj-1234	313	12	impact	impact	NOUN
cuesj-1234	313	13	on	on	ADP
cuesj-1234	313	14	the	the	DET
cuesj-1234	313	15	determination	determination	NOUN
cuesj-1234	313	16	of	of	ADP
cuesj-1234	313	17	solubility	solubility	NOUN
cuesj-1234	313	18	and	and	CCONJ
cuesj-1234	313	19	nucleation	nucleation	NOUN
cuesj-1234	313	20	kinetics	kinetic	NOUN
cuesj-1234	313	21	.	.	PUNCT
cuesj-1234	314	1	journal	journal	PROPN
cuesj-1234	314	2	crystal	crystal	NOUN
cuesj-1234	314	3	growth	growth	NOUN
cuesj-1234	314	4	,	,	PUNCT
cuesj-1234	314	5	vol	vol	NOUN
cuesj-1234	314	6	.	.	PROPN
cuesj-1234	315	1	519	519	NUM
cuesj-1234	315	2	,	,	PUNCT
cuesj-1234	315	3	pp	pp	ADJ
cuesj-1234	315	4	.	.	PUNCT
cuesj-1234	316	1	91	91	NUM
cuesj-1234	316	2	-	-	SYM
cuesj-1234	316	3	99	99	NUM
cuesj-1234	316	4	,	,	PUNCT
cuesj-1234	316	5	2019	2019	NUM
cuesj-1234	316	6	.	.	PUNCT