id	sid	tid	token	lemma	pos
clinmedi-182	1	1	cmi	cmi	PROPN
clinmedi-182	1	2	04	04	NUM
clinmedi-182	1	3	(	(	PUNCT
clinmedi-182	1	4	03	03	NUM
clinmedi-182	1	5	)	)	PUNCT
clinmedi-182	1	6	,	,	PUNCT
clinmedi-182	1	7	415−429	415−429	PROPN
clinmedi-182	1	8	cmi	cmi	PROPN
clinmedi-182	1	9	journal	journal	NOUN
clinmedi-182	1	10	415	415	NUM
clinmedi-182	1	11	clinical	clinical	ADJ
clinmedi-182	1	12	medicine	medicine	NOUN
clinmedi-182	1	13	insights	insight	NOUN
clinmedi-182	1	14	doi	doi	NOUN
clinmedi-182	1	15	:	:	PUNCT
clinmedi-182	1	16	https://doi.org/10.52845	https://doi.org/10.52845	ADJ
clinmedi-182	1	17	/	/	SYM
clinmedi-182	1	18	cmi/2023	cmi/2023	NOUN
clinmedi-182	1	19	-	-	PUNCT
clinmedi-182	1	20	4	4	NUM
clinmedi-182	1	21	-	-	PUNCT
clinmedi-182	1	22	3	3	NUM
clinmedi-182	1	23	-	-	SYM
clinmedi-182	1	24	3	3	NUM
clinmedi-182	1	25	cmi	cmi	NOUN
clinmedi-182	1	26	04	04	NUM
clinmedi-182	1	27	(	(	PUNCT
clinmedi-182	1	28	03	03	NUM
clinmedi-182	1	29	)	)	PUNCT
clinmedi-182	1	30	,	,	PUNCT
clinmedi-182	1	31	415	415	NUM
clinmedi-182	1	32	-	-	SYM
clinmedi-182	1	33	429	429	NUM
clinmedi-182	1	34	(	(	PUNCT
clinmedi-182	1	35	2023	2023	NUM
clinmedi-182	1	36	)	)	PUNCT
clinmedi-182	1	37	issn	issn	PROPN
clinmedi-182	1	38	(	(	PUNCT
clinmedi-182	1	39	o	o	NOUN
clinmedi-182	1	40	)	)	PUNCT
clinmedi-182	1	41	2694	2694	NUM
clinmedi-182	1	42	-	-	SYM
clinmedi-182	1	43	4626	4626	NUM
clinmedi-182	1	44	original	original	ADJ
clinmedi-182	1	45	article	article	NOUN
clinmedi-182	1	46	efficacy	efficacy	NOUN
clinmedi-182	1	47	of	of	ADP
clinmedi-182	1	48	highand	highand	ADJ
clinmedi-182	1	49	low	low	ADJ
clinmedi-182	1	50	-	-	PUNCT
clinmedi-182	1	51	dose	dose	NOUN
clinmedi-182	1	52	,	,	PUNCT
clinmedi-182	1	53	highly	highly	ADV
clinmedi-182	1	54	bioavailable	bioavailable	ADJ
clinmedi-182	1	55	curcumin	curcumin	NOUN
clinmedi-182	1	56	(	(	PUNCT
clinmedi-182	1	57	curcurouge	curcurouge	ADJ
clinmedi-182	1	58	®	®	NOUN
clinmedi-182	1	59	)	)	PUNCT
clinmedi-182	1	60	for	for	ADP
clinmedi-182	1	61	treating	treat	VERB
clinmedi-182	1	62	knee	knee	NOUN
clinmedi-182	1	63	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	1	64	:	:	PUNCT
clinmedi-182	1	65	a	a	DET
clinmedi-182	1	66	randomized	randomized	ADJ
clinmedi-182	1	67	,	,	PUNCT
clinmedi-182	1	68	doubleblind	doubleblind	NOUN
clinmedi-182	1	69	,	,	PUNCT
clinmedi-182	1	70	placebo	placebo	NOUN
clinmedi-182	1	71	-	-	PUNCT
clinmedi-182	1	72	controlled	control	VERB
clinmedi-182	1	73	prospective	prospective	ADJ
clinmedi-182	1	74	study	study	NOUN
clinmedi-182	1	75	yasuaki	yasuaki	NOUN
clinmedi-182	1	76	nakagawa	nakagawa	PROPN
clinmedi-182	1	77	m.d	m.d	PROPN
clinmedi-182	1	78	.	.	PROPN
clinmedi-182	1	79	1,2	1,2	NUM
clinmedi-182	1	80	,	,	PUNCT
clinmedi-182	1	81	shigeru	shigeru	PROPN
clinmedi-182	1	82	yamada	yamada	PROPN
clinmedi-182	1	83	m.d	m.d	PROPN
clinmedi-182	1	84	.	.	PROPN
clinmedi-182	1	85	3	3	NUM
clinmedi-182	1	86	,	,	PUNCT
clinmedi-182	1	87	shogo	shogo	PROPN
clinmedi-182	1	88	mukai	mukai	PROPN
clinmedi-182	1	89	m.d	m.d	PROPN
clinmedi-182	1	90	.	.	PROPN
clinmedi-182	1	91	3	3	NUM
clinmedi-182	1	92	,	,	PUNCT
clinmedi-182	1	93	kaori	kaori	PROPN
clinmedi-182	1	94	akiyoshi	akiyoshi	VERB
clinmedi-182	1	95	4	4	NUM
clinmedi-182	1	96	,	,	PUNCT
clinmedi-182	1	97	yasuhiro	yasuhiro	VERB
clinmedi-182	1	98	katsuura	katsuura	PROPN
clinmedi-182	1	99	5	5	NUM
clinmedi-182	1	100	,	,	PUNCT
clinmedi-182	1	101	tadashi	tadashi	PROPN
clinmedi-182	1	102	hashimoto	hashimoto	NOUN
clinmedi-182	1	103	5	5	NUM
clinmedi-182	1	104	1	1	NUM
clinmedi-182	1	105	clinical	clinical	ADJ
clinmedi-182	1	106	research	research	NOUN
clinmedi-182	1	107	center	center	NOUN
clinmedi-182	1	108	,	,	PUNCT
clinmedi-182	1	109	national	national	ADJ
clinmedi-182	1	110	hospital	hospital	PROPN
clinmedi-182	1	111	organization	organization	PROPN
clinmedi-182	1	112	kyoto	kyoto	PROPN
clinmedi-182	1	113	medical	medical	ADJ
clinmedi-182	1	114	center	center	PROPN
clinmedi-182	1	115	,	,	PUNCT
clinmedi-182	1	116	japan	japan	PROPN
clinmedi-182	1	117	2	2	NUM
clinmedi-182	1	118	department	department	NOUN
clinmedi-182	1	119	of	of	ADP
clinmedi-182	1	120	orthopaedic	orthopaedic	ADJ
clinmedi-182	1	121	surgery	surgery	NOUN
clinmedi-182	1	122	,	,	PUNCT
clinmedi-182	1	123	japan	japan	PROPN
clinmedi-182	1	124	baptist	baptist	PROPN
clinmedi-182	1	125	medical	medical	PROPN
clinmedi-182	1	126	foundation	foundation	PROPN
clinmedi-182	1	127	,	,	PUNCT
clinmedi-182	1	128	japan	japan	PROPN
clinmedi-182	1	129	3	3	PROPN
clinmedi-182	1	130	department	department	NOUN
clinmedi-182	1	131	of	of	ADP
clinmedi-182	1	132	orthopaedic	orthopaedic	ADJ
clinmedi-182	1	133	surgery	surgery	NOUN
clinmedi-182	1	134	,	,	PUNCT
clinmedi-182	1	135	national	national	ADJ
clinmedi-182	1	136	hospital	hospital	NOUN
clinmedi-182	1	137	organization	organization	PROPN
clinmedi-182	1	138	4	4	NUM
clinmedi-182	1	139	department	department	NOUN
clinmedi-182	1	140	of	of	ADP
clinmedi-182	1	141	medical	medical	ADJ
clinmedi-182	1	142	infomatics	infomatic	NOUN
clinmedi-182	1	143	,	,	PUNCT
clinmedi-182	1	144	national	national	ADJ
clinmedi-182	1	145	hospital	hospital	NOUN
clinmedi-182	1	146	organization	organization	NOUN
clinmedi-182	1	147	5	5	NUM
clinmedi-182	1	148	therabiopharma	therabiopharma	NOUN
clinmedi-182	1	149	incorporation	incorporation	NOUN
clinmedi-182	1	150	,	,	PUNCT
clinmedi-182	1	151	japan	japan	PROPN
clinmedi-182	1	152	*	*	PUNCT
clinmedi-182	1	153	corresponding	correspond	VERB
clinmedi-182	1	154	author	author	NOUN
clinmedi-182	1	155	:	:	PUNCT
clinmedi-182	1	156	yasuaki	yasuaki	PROPN
clinmedi-182	1	157	nakagawa	nakagawa	PROPN
clinmedi-182	1	158	,	,	PUNCT
clinmedi-182	1	159	md	md	PROPN
clinmedi-182	1	160	abstract	abstract	NOUN
clinmedi-182	1	161	:	:	PUNCT
clinmedi-182	1	162	purposes	purpose	NOUN
clinmedi-182	1	163	:	:	PUNCT
clinmedi-182	1	164	to	to	PART
clinmedi-182	1	165	evaluate	evaluate	VERB
clinmedi-182	1	166	the	the	DET
clinmedi-182	1	167	clinical	clinical	ADJ
clinmedi-182	1	168	effects	effect	NOUN
clinmedi-182	1	169	of	of	ADP
clinmedi-182	1	170	orally	orally	ADV
clinmedi-182	1	171	administered	administer	VERB
clinmedi-182	1	172	curcurouge	curcurouge	NOUN
clinmedi-182	1	173	○	○	PROPN
clinmedi-182	1	174	r	r	NOUN
clinmedi-182	1	175	in	in	ADP
clinmedi-182	1	176	patients	patient	NOUN
clinmedi-182	1	177	with	with	ADP
clinmedi-182	1	178	knee	knee	NOUN
clinmedi-182	1	179	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	1	180	(	(	PUNCT
clinmedi-182	1	181	oa	oa	INTJ
clinmedi-182	1	182	)	)	PUNCT
clinmedi-182	1	183	after	after	ADP
clinmedi-182	1	184	12	12	NUM
clinmedi-182	1	185	weeks	week	NOUN
clinmedi-182	1	186	of	of	ADP
clinmedi-182	1	187	treatment	treatment	NOUN
clinmedi-182	1	188	.	.	PUNCT
clinmedi-182	2	1	methods	method	NOUN
clinmedi-182	2	2	:	:	PUNCT
clinmedi-182	2	3	in	in	ADP
clinmedi-182	2	4	this	this	DET
clinmedi-182	2	5	randomized	randomize	VERB
clinmedi-182	2	6	,	,	PUNCT
clinmedi-182	2	7	double	double	ADJ
clinmedi-182	2	8	-	-	PUNCT
clinmedi-182	2	9	blind	blind	ADJ
clinmedi-182	2	10	,	,	PUNCT
clinmedi-182	2	11	placebo	placebo	NOUN
clinmedi-182	2	12	-	-	PUNCT
clinmedi-182	2	13	controlled	control	VERB
clinmedi-182	2	14	,	,	PUNCT
clinmedi-182	2	15	prospective	prospective	ADJ
clinmedi-182	2	16	clinical	clinical	ADJ
clinmedi-182	2	17	study	study	NOUN
clinmedi-182	2	18	.	.	PUNCT
clinmedi-182	3	1	90	90	NUM
clinmedi-182	3	2	patients	patient	NOUN
clinmedi-182	3	3	over	over	ADP
clinmedi-182	3	4	the	the	DET
clinmedi-182	3	5	age	age	NOUN
clinmedi-182	3	6	40	40	NUM
clinmedi-182	3	7	with	with	ADP
clinmedi-182	3	8	knee	knee	NOUN
clinmedi-182	3	9	oa	oa	PROPN
clinmedi-182	3	10	of	of	ADP
clinmedi-182	3	11	kellgren	kellgren	PROPN
clinmedi-182	3	12	-	-	PUNCT
clinmedi-182	3	13	lawrence	lawrence	PROPN
clinmedi-182	3	14	(	(	PUNCT
clinmedi-182	3	15	kl	kl	PROPN
clinmedi-182	3	16	)	)	PUNCT
clinmedi-182	3	17	grade	grade	NOUN
clinmedi-182	3	18	ii	ii	PROPN
clinmedi-182	3	19	or	or	CCONJ
clinmedi-182	3	20	iii	iii	NOUN
clinmedi-182	3	21	were	be	AUX
clinmedi-182	3	22	enrolled	enrol	VERB
clinmedi-182	3	23	.	.	PUNCT
clinmedi-182	4	1	a	a	DET
clinmedi-182	4	2	placebo	placebo	NOUN
clinmedi-182	4	3	or	or	CCONJ
clinmedi-182	4	4	curcurouge	curcurouge	NOUN
clinmedi-182	4	5	○	○	NOUN
clinmedi-182	4	6	r	r	NOUN
clinmedi-182	4	7	containing	contain	VERB
clinmedi-182	4	8	60	60	NUM
clinmedi-182	4	9	mg	mg	ADP
clinmedi-182	4	10	or	or	CCONJ
clinmedi-182	4	11	180	180	NUM
clinmedi-182	4	12	mg	mg	NUM
clinmedi-182	4	13	/	/	SYM
clinmedi-182	4	14	day	day	NOUN
clinmedi-182	4	15	of	of	ADP
clinmedi-182	4	16	curcumin	curcumin	NOUN
clinmedi-182	4	17	was	be	AUX
clinmedi-182	4	18	administered	administer	VERB
clinmedi-182	4	19	orally	orally	ADV
clinmedi-182	4	20	every	every	DET
clinmedi-182	4	21	day	day	NOUN
clinmedi-182	4	22	for	for	ADP
clinmedi-182	4	23	12	12	NUM
clinmedi-182	4	24	weeks	week	NOUN
clinmedi-182	4	25	.	.	PUNCT
clinmedi-182	5	1	to	to	PART
clinmedi-182	5	2	monitor	monitor	VERB
clinmedi-182	5	3	adverse	adverse	ADJ
clinmedi-182	5	4	events	event	NOUN
clinmedi-182	5	5	,	,	PUNCT
clinmedi-182	5	6	blood	blood	NOUN
clinmedi-182	5	7	biochemical	biochemical	ADJ
clinmedi-182	5	8	analyses	analysis	NOUN
clinmedi-182	5	9	were	be	AUX
clinmedi-182	5	10	performed	perform	VERB
clinmedi-182	5	11	before	before	ADV
clinmedi-182	5	12	and	and	CCONJ
clinmedi-182	5	13	after	after	ADP
clinmedi-182	5	14	12	12	NUM
clinmedi-182	5	15	weeks	week	NOUN
clinmedi-182	5	16	of	of	ADP
clinmedi-182	5	17	each	each	DET
clinmedi-182	5	18	intervention	intervention	NOUN
clinmedi-182	5	19	.	.	PUNCT
clinmedi-182	6	1	the	the	DET
clinmedi-182	6	2	patients	patient	NOUN
clinmedi-182	6	3	’	'	PUNCT
clinmedi-182	6	4	knee	knee	NOUN
clinmedi-182	6	5	symptoms	symptom	NOUN
clinmedi-182	6	6	were	be	AUX
clinmedi-182	6	7	evaluated	evaluate	VERB
clinmedi-182	6	8	for	for	ADP
clinmedi-182	6	9	12	12	NUM
clinmedi-182	6	10	weeks	week	NOUN
clinmedi-182	6	11	using	use	VERB
clinmedi-182	6	12	the	the	DET
clinmedi-182	6	13	japanese	japanese	ADJ
clinmedi-182	6	14	knee	knee	NOUN
clinmedi-182	6	15	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	6	16	measure	measure	NOUN
clinmedi-182	6	17	(	(	PUNCT
clinmedi-182	6	18	jkom	jkom	NOUN
clinmedi-182	6	19	)	)	PUNCT
clinmedi-182	6	20	criteria	criterion	NOUN
clinmedi-182	6	21	,	,	PUNCT
clinmedi-182	6	22	a	a	DET
clinmedi-182	6	23	knee	knee	NOUN
clinmedi-182	6	24	pain	pain	NOUN
clinmedi-182	6	25	visual	visual	ADJ
clinmedi-182	6	26	analog	analog	NOUN
clinmedi-182	6	27	scale	scale	NOUN
clinmedi-182	6	28	(	(	PUNCT
clinmedi-182	6	29	vas	vas	NOUN
clinmedi-182	6	30	)	)	PUNCT
clinmedi-182	6	31	,	,	PUNCT
clinmedi-182	6	32	the	the	DET
clinmedi-182	6	33	japanese	japanese	ADJ
clinmedi-182	6	34	orthopedic	orthopedic	ADJ
clinmedi-182	6	35	association	association	PROPN
clinmedi-182	6	36	(	(	PUNCT
clinmedi-182	6	37	joa	joa	NOUN
clinmedi-182	6	38	)	)	PUNCT
clinmedi-182	6	39	knee	knee	NOUN
clinmedi-182	6	40	scoring	scoring	NOUN
clinmedi-182	6	41	system	system	NOUN
clinmedi-182	6	42	,	,	PUNCT
clinmedi-182	6	43	the	the	DET
clinmedi-182	6	44	need	need	NOUN
clinmedi-182	6	45	for	for	ADP
clinmedi-182	6	46	nonsteroidal	nonsteroidal	NOUN
clinmedi-182	6	47	anti	anti	ADJ
clinmedi-182	6	48	-	-	ADJ
clinmedi-182	6	49	inflammatory	inflammatory	ADJ
clinmedi-182	6	50	drugs	drug	NOUN
clinmedi-182	6	51	(	(	PUNCT
clinmedi-182	6	52	nsaids	nsaid	NOUN
clinmedi-182	6	53	)	)	PUNCT
clinmedi-182	6	54	and	and	CCONJ
clinmedi-182	6	55	a	a	DET
clinmedi-182	6	56	timed	time	VERB
clinmedi-182	6	57	up	up	ADP
clinmedi-182	6	58	-	-	PUNCT
clinmedi-182	6	59	and	and	CCONJ
clinmedi-182	6	60	-	-	PUNCT
clinmedi-182	6	61	go	go	VERB
clinmedi-182	6	62	test	test	NOUN
clinmedi-182	6	63	(	(	PUNCT
clinmedi-182	6	64	tug	tug	NOUN
clinmedi-182	6	65	)	)	PUNCT
clinmedi-182	6	66	.	.	PUNCT
clinmedi-182	7	1	results	result	NOUN
clinmedi-182	7	2	:	:	PUNCT
clinmedi-182	7	3	the	the	DET
clinmedi-182	7	4	declining	decline	VERB
clinmedi-182	7	5	trend	trend	NOUN
clinmedi-182	7	6	in	in	ADP
clinmedi-182	7	7	nsaids	nsaid	NOUN
clinmedi-182	7	8	needs	need	NOUN
clinmedi-182	7	9	was	be	AUX
clinmedi-182	7	10	significantly	significantly	ADV
clinmedi-182	7	11	greater	great	ADJ
clinmedi-182	7	12	in	in	ADP
clinmedi-182	7	13	high	high	ADJ
clinmedi-182	7	14	-	-	PUNCT
clinmedi-182	7	15	dose	dose	NOUN
clinmedi-182	7	16	curcurouge	curcurouge	NOUN
clinmedi-182	7	17	○	○	PROPN
clinmedi-182	7	18	r	r	NOUN
clinmedi-182	7	19	group	group	NOUN
clinmedi-182	7	20	than	than	ADP
clinmedi-182	7	21	in	in	ADP
clinmedi-182	7	22	placebo	placebo	NOUN
clinmedi-182	7	23	group	group	NOUN
clinmedi-182	7	24	.	.	PUNCT
clinmedi-182	8	1	the	the	DET
clinmedi-182	8	2	decrease	decrease	NOUN
clinmedi-182	8	3	of	of	ADP
clinmedi-182	8	4	highly	highly	ADV
clinmedi-182	8	5	sensitive	sensitive	ADJ
clinmedi-182	8	6	crp	crp	PROPN
clinmedi-182	8	7	was	be	AUX
clinmedi-182	8	8	significantly	significantly	ADV
clinmedi-182	8	9	greater	great	ADJ
clinmedi-182	8	10	in	in	ADP
clinmedi-182	8	11	high	high	ADV
clinmedi-182	8	12	-	-	PUNCT
clinmedi-182	8	13	dose	dose	NOUN
clinmedi-182	8	14	of	of	ADP
clinmedi-182	8	15	curcurouge	curcurouge	ADJ
clinmedi-182	8	16	®	®	NOUN
clinmedi-182	8	17	than	than	ADP
clinmedi-182	8	18	placebo	placebo	NOUN
clinmedi-182	8	19	group	group	NOUN
clinmedi-182	8	20	.	.	PUNCT
clinmedi-182	9	1	in	in	ADP
clinmedi-182	9	2	patients	patient	NOUN
clinmedi-182	9	3	with	with	ADP
clinmedi-182	9	4	kl	kl	PROPN
clinmedi-182	9	5	grade	grade	PROPN
clinmedi-182	9	6	ii	ii	PROPN
clinmedi-182	9	7	,	,	PUNCT
clinmedi-182	9	8	joa	joa	NOUN
clinmedi-182	9	9	and	and	CCONJ
clinmedi-182	9	10	vas	vas	NOUN
clinmedi-182	9	11	scores	score	NOUN
clinmedi-182	9	12	improved	improve	VERB
clinmedi-182	9	13	significantly	significantly	ADV
clinmedi-182	9	14	more	more	ADV
clinmedi-182	9	15	in	in	ADP
clinmedi-182	9	16	the	the	DET
clinmedi-182	9	17	high	high	ADJ
clinmedi-182	9	18	-	-	PUNCT
clinmedi-182	9	19	dose	dose	NOUN
clinmedi-182	9	20	curcurouge	curcurouge	NOUN
clinmedi-182	9	21	○	○	PROPN
clinmedi-182	9	22	r	r	NOUN
clinmedi-182	9	23	group	group	NOUN
clinmedi-182	9	24	than	than	ADP
clinmedi-182	9	25	in	in	ADP
clinmedi-182	9	26	the	the	DET
clinmedi-182	9	27	placebo	placebo	NOUN
clinmedi-182	9	28	group	group	NOUN
clinmedi-182	9	29	.	.	PUNCT
clinmedi-182	10	1	we	we	PRON
clinmedi-182	10	2	did	do	AUX
clinmedi-182	10	3	n’t	not	PART
clinmedi-182	10	4	find	find	VERB
clinmedi-182	10	5	curcurouge	curcurouge	ADJ
clinmedi-182	10	6	®	®	NOUN
clinmedi-182	10	7	related	relate	VERB
clinmedi-182	10	8	adverse	adverse	ADJ
clinmedi-182	10	9	event	event	NOUN
clinmedi-182	10	10	during	during	ADP
clinmedi-182	10	11	the	the	DET
clinmedi-182	10	12	study	study	NOUN
clinmedi-182	10	13	period	period	NOUN
clinmedi-182	10	14	.	.	PUNCT
clinmedi-182	11	1	conclusion	conclusion	NOUN
clinmedi-182	11	2	:	:	PUNCT
clinmedi-182	11	3	curcurouge	curcurouge	PROPN
clinmedi-182	11	4	○	○	PROPN
clinmedi-182	11	5	r	r	NOUN
clinmedi-182	11	6	has	have	AUX
clinmedi-182	11	7	succeeded	succeed	VERB
clinmedi-182	11	8	in	in	ADP
clinmedi-182	11	9	proofing	proof	VERB
clinmedi-182	11	10	a	a	DET
clinmedi-182	11	11	potential	potential	NOUN
clinmedi-182	11	12	for	for	ADP
clinmedi-182	11	13	treating	treat	VERB
clinmedi-182	11	14	human	human	ADJ
clinmedi-182	11	15	knee	knee	NOUN
clinmedi-182	11	16	oa	oa	INTJ
clinmedi-182	11	17	,	,	PUNCT
clinmedi-182	11	18	particularly	particularly	ADV
clinmedi-182	11	19	at	at	ADP
clinmedi-182	11	20	an	an	DET
clinmedi-182	11	21	early	early	ADJ
clinmedi-182	11	22	stage	stage	NOUN
clinmedi-182	11	23	.	.	PUNCT
clinmedi-182	12	1	trial	trial	NOUN
clinmedi-182	12	2	registration	registration	NOUN
clinmedi-182	12	3	:	:	PUNCT
clinmedi-182	12	4	jrcts	jrct	NOUN
clinmedi-182	12	5	051200058	051200058	NUM
clinmedi-182	12	6	keywords	keyword	NOUN
clinmedi-182	12	7	:	:	PUNCT
clinmedi-182	12	8	knee	knee	NOUN
clinmedi-182	12	9	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	12	10	,	,	PUNCT
clinmedi-182	12	11	treatment	treatment	NOUN
clinmedi-182	12	12	,	,	PUNCT
clinmedi-182	12	13	safety	safety	NOUN
clinmedi-182	12	14	,	,	PUNCT
clinmedi-182	12	15	highly	highly	ADV
clinmedi-182	12	16	bioavailable	bioavailable	ADJ
clinmedi-182	12	17	curcumin	curcumin	NOUN
clinmedi-182	12	18	,	,	PUNCT
clinmedi-182	12	19	curcurouge	curcurouge	NOUN
clinmedi-182	12	20	○	○	PROPN
clinmedi-182	12	21	r	r	NOUN
clinmedi-182	12	22	level	level	NOUN
clinmedi-182	12	23	of	of	ADP
clinmedi-182	12	24	evidence	evidence	NOUN
clinmedi-182	12	25	:	:	PUNCT
clinmedi-182	12	26	level	level	NOUN
clinmedi-182	13	1	i	i	PRON
clinmedi-182	13	2	,	,	PUNCT
clinmedi-182	13	3	a	a	DET
clinmedi-182	13	4	randomized	randomized	ADJ
clinmedi-182	13	5	,	,	PUNCT
clinmedi-182	13	6	double	double	ADJ
clinmedi-182	13	7	-	-	PUNCT
clinmedi-182	13	8	blind	blind	ADJ
clinmedi-182	13	9	,	,	PUNCT
clinmedi-182	13	10	placebo	placebo	NOUN
clinmedi-182	13	11	-	-	PUNCT
clinmedi-182	13	12	controlled	control	VERB
clinmedi-182	13	13	prospective	prospective	ADJ
clinmedi-182	13	14	study	study	NOUN
clinmedi-182	13	15	copyright	copyright	NOUN
clinmedi-182	13	16	:	:	PUNCT
clinmedi-182	13	17	©	©	PROPN
clinmedi-182	13	18	2021	2021	NUM
clinmedi-182	13	19	the	the	DET
clinmedi-182	13	20	authors	author	NOUN
clinmedi-182	13	21	.	.	PUNCT
clinmedi-182	14	1	published	publish	VERB
clinmedi-182	14	2	by	by	ADP
clinmedi-182	14	3	medical	medical	ADJ
clinmedi-182	14	4	editor	editor	NOUN
clinmedi-182	14	5	and	and	CCONJ
clinmedi-182	14	6	educational	educational	ADJ
clinmedi-182	14	7	research	research	NOUN
clinmedi-182	14	8	publishers	publishers	PROPN
clinmedi-182	14	9	ltd	ltd	PROPN
clinmedi-182	14	10	.	.	PUNCT
clinmedi-182	15	1	this	this	PRON
clinmedi-182	15	2	is	be	AUX
clinmedi-182	15	3	an	an	DET
clinmedi-182	15	4	open	open	ADJ
clinmedi-182	15	5	access	access	NOUN
clinmedi-182	15	6	article	article	NOUN
clinmedi-182	15	7	under	under	ADP
clinmedi-182	15	8	the	the	DET
clinmedi-182	15	9	cc	cc	PROPN
clinmedi-182	15	10	by	by	ADP
clinmedi-182	15	11	-	-	PUNCT
clinmedi-182	15	12	nc	nc	VERB
clinmedi-182	15	13	-	-	PUNCT
clinmedi-182	15	14	nd	nd	NOUN
clinmedi-182	15	15	license	license	NOUN
clinmedi-182	15	16	(	(	PUNCT
clinmedi-182	15	17	https://creativecommons.org/lic	https://creativecommons.org/lic	PROPN
clinmedi-182	15	18	enses	ense	NOUN
clinmedi-182	15	19	/	/	SYM
clinmedi-182	15	20	bync	bync	NOUN
clinmedi-182	15	21	-	-	PUNCT
clinmedi-182	15	22	nd/4.0/	nd/4.0/	NOUN
clinmedi-182	15	23	)	)	PUNCT
clinmedi-182	15	24	.	.	PUNCT
clinmedi-182	16	1	https://creativecommons.org/lic%20enses/by-nc-nd/4.0/	https://creativecommons.org/lic%20enses/by-nc-nd/4.0/	NOUN
clinmedi-182	17	1	https://creativecommons.org/lic%20enses/by-nc-nd/4.0/	https://creativecommons.org/lic%20enses/by-nc-nd/4.0/	PRON
clinmedi-182	17	2	cmi	cmi	NOUN
clinmedi-182	17	3	04	04	PROPN
clinmedi-182	17	4	(	(	PUNCT
clinmedi-182	17	5	03	03	NUM
clinmedi-182	17	6	)	)	PUNCT
clinmedi-182	17	7	,	,	PUNCT
clinmedi-182	17	8	415−429	415−429	PROPN
clinmedi-182	17	9	cmi	cmi	PROPN
clinmedi-182	17	10	journal	journal	PROPN
clinmedi-182	17	11	416	416	NUM
clinmedi-182	17	12	cmi	cmi	PROPN
clinmedi-182	17	13	journal	journal	PROPN
clinmedi-182	17	14	yasuaki	yasuaki	PROPN
clinmedi-182	17	15	nakagawa	nakagawa	PROPN
clinmedi-182	17	16	,	,	PUNCT
clinmedi-182	17	17	md	md	PROPN
clinmedi-182	17	18	introduction	introduction	NOUN
clinmedi-182	17	19	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	17	20	(	(	PUNCT
clinmedi-182	17	21	oa	oa	X
clinmedi-182	17	22	)	)	PUNCT
clinmedi-182	17	23	is	be	AUX
clinmedi-182	17	24	a	a	DET
clinmedi-182	17	25	common	common	ADJ
clinmedi-182	17	26	degenerative	degenerative	ADJ
clinmedi-182	17	27	disease	disease	NOUN
clinmedi-182	17	28	that	that	PRON
clinmedi-182	17	29	causes	cause	VERB
clinmedi-182	17	30	disability	disability	NOUN
clinmedi-182	17	31	and	and	CCONJ
clinmedi-182	17	32	poor	poor	ADJ
clinmedi-182	17	33	quality	quality	NOUN
clinmedi-182	17	34	of	of	ADP
clinmedi-182	17	35	life	life	NOUN
clinmedi-182	17	36	.	.	PUNCT
clinmedi-182	18	1	it	it	PRON
clinmedi-182	18	2	affects	affect	VERB
clinmedi-182	18	3	approximately	approximately	ADV
clinmedi-182	18	4	240	240	NUM
clinmedi-182	18	5	million	million	NUM
clinmedi-182	18	6	people	people	NOUN
clinmedi-182	18	7	worldwide	worldwide	ADV
clinmedi-182	18	8	,	,	PUNCT
clinmedi-182	18	9	with	with	ADP
clinmedi-182	18	10	10	10	NUM
clinmedi-182	18	11	%	%	NOUN
clinmedi-182	18	12	of	of	ADP
clinmedi-182	18	13	men	man	NOUN
clinmedi-182	18	14	and	and	CCONJ
clinmedi-182	18	15	18	18	NUM
clinmedi-182	18	16	%	%	NOUN
clinmedi-182	18	17	of	of	ADP
clinmedi-182	18	18	women	woman	NOUN
clinmedi-182	18	19	affected	affect	VERB
clinmedi-182	18	20	[	[	PUNCT
clinmedi-182	18	21	1	1	NUM
clinmedi-182	18	22	]	]	PUNCT
clinmedi-182	18	23	.	.	PUNCT
clinmedi-182	19	1	hip	hip	NOUN
clinmedi-182	19	2	or	or	CCONJ
clinmedi-182	19	3	knee	knee	NOUN
clinmedi-182	19	4	oa	oa	X
clinmedi-182	19	5	is	be	AUX
clinmedi-182	19	6	a	a	DET
clinmedi-182	19	7	chronic	chronic	ADJ
clinmedi-182	19	8	condition	condition	NOUN
clinmedi-182	19	9	mostly	mostly	ADV
clinmedi-182	19	10	treated	treat	VERB
clinmedi-182	19	11	with	with	ADP
clinmedi-182	19	12	analgesics	analgesic	NOUN
clinmedi-182	19	13	and	and	CCONJ
clinmedi-182	19	14	nonsteroidal	nonsteroidal	NOUN
clinmedi-182	19	15	anti	anti	ADJ
clinmedi-182	19	16	-	-	ADJ
clinmedi-182	19	17	inflammatory	inflammatory	ADJ
clinmedi-182	19	18	drugs	drug	NOUN
clinmedi-182	19	19	(	(	PUNCT
clinmedi-182	19	20	nsaids	nsaid	NOUN
clinmedi-182	19	21	)	)	PUNCT
clinmedi-182	19	22	,	,	PUNCT
clinmedi-182	19	23	but	but	CCONJ
clinmedi-182	19	24	these	these	DET
clinmedi-182	19	25	medications	medication	NOUN
clinmedi-182	19	26	can	can	AUX
clinmedi-182	19	27	cause	cause	VERB
clinmedi-182	19	28	serious	serious	ADJ
clinmedi-182	19	29	gastrointestinal	gastrointestinal	ADJ
clinmedi-182	19	30	and	and	CCONJ
clinmedi-182	19	31	cardiovascular	cardiovascular	ADJ
clinmedi-182	19	32	adverse	adverse	ADJ
clinmedi-182	19	33	events	event	NOUN
clinmedi-182	19	34	,	,	PUNCT
clinmedi-182	19	35	especially	especially	ADV
clinmedi-182	19	36	with	with	ADP
clinmedi-182	19	37	longterm	longterm	ADJ
clinmedi-182	19	38	use	use	NOUN
clinmedi-182	19	39	[	[	X
clinmedi-182	19	40	2,3	2,3	NUM
clinmedi-182	19	41	]	]	PUNCT
clinmedi-182	19	42	.	.	PUNCT
clinmedi-182	20	1	thus	thus	ADV
clinmedi-182	20	2	,	,	PUNCT
clinmedi-182	20	3	disease	disease	NOUN
clinmedi-182	20	4	-	-	PUNCT
clinmedi-182	20	5	modifying	modify	VERB
clinmedi-182	20	6	agents	agent	NOUN
clinmedi-182	20	7	that	that	PRON
clinmedi-182	20	8	not	not	PART
clinmedi-182	20	9	only	only	ADV
clinmedi-182	20	10	alleviate	alleviate	VERB
clinmedi-182	20	11	joint	joint	ADJ
clinmedi-182	20	12	pain	pain	NOUN
clinmedi-182	20	13	but	but	CCONJ
clinmedi-182	20	14	also	also	ADV
clinmedi-182	20	15	slow	slow	VERB
clinmedi-182	20	16	the	the	DET
clinmedi-182	20	17	progression	progression	NOUN
clinmedi-182	20	18	of	of	ADP
clinmedi-182	20	19	the	the	DET
clinmedi-182	20	20	condition	condition	NOUN
clinmedi-182	20	21	are	be	AUX
clinmedi-182	20	22	required	require	VERB
clinmedi-182	20	23	.	.	PUNCT
clinmedi-182	21	1	curcumin	curcumin	NOUN
clinmedi-182	21	2	is	be	AUX
clinmedi-182	21	3	a	a	DET
clinmedi-182	21	4	polyphenol	polyphenol	NOUN
clinmedi-182	21	5	extracted	extract	VERB
clinmedi-182	21	6	from	from	ADP
clinmedi-182	21	7	turmeric	turmeric	NOUN
clinmedi-182	21	8	,	,	PUNCT
clinmedi-182	21	9	that	that	PRON
clinmedi-182	21	10	has	have	AUX
clinmedi-182	21	11	long	long	ADV
clinmedi-182	21	12	been	be	AUX
clinmedi-182	21	13	used	use	VERB
clinmedi-182	21	14	safely	safely	ADV
clinmedi-182	21	15	in	in	ADP
clinmedi-182	21	16	foods	food	NOUN
clinmedi-182	21	17	like	like	ADP
clinmedi-182	21	18	curry	curry	NOUN
clinmedi-182	21	19	[	[	X
clinmedi-182	21	20	4	4	NUM
clinmedi-182	21	21	]	]	PUNCT
clinmedi-182	21	22	.	.	PUNCT
clinmedi-182	22	1	curcumin	curcumin	PROPN
clinmedi-182	22	2	,	,	PUNCT
clinmedi-182	22	3	a	a	DET
clinmedi-182	22	4	promising	promising	ADJ
clinmedi-182	22	5	therapeutic	therapeutic	ADJ
clinmedi-182	22	6	food	food	NOUN
clinmedi-182	22	7	material	material	NOUN
clinmedi-182	22	8	with	with	ADP
clinmedi-182	22	9	anti	anti	ADJ
clinmedi-182	22	10	-	-	ADJ
clinmedi-182	22	11	inflammatory	inflammatory	ADJ
clinmedi-182	22	12	and	and	CCONJ
clinmedi-182	22	13	anti	anti	ADJ
clinmedi-182	22	14	-	-	ADJ
clinmedi-182	22	15	oxidative	oxidative	ADJ
clinmedi-182	22	16	properties	property	NOUN
clinmedi-182	22	17	;	;	PUNCT
clinmedi-182	22	18	has	have	AUX
clinmedi-182	22	19	long	long	ADV
clinmedi-182	22	20	been	be	AUX
clinmedi-182	22	21	used	use	VERB
clinmedi-182	22	22	as	as	ADP
clinmedi-182	22	23	an	an	DET
clinmedi-182	22	24	antiinflammatory	antiinflammatory	NOUN
clinmedi-182	22	25	treatment	treatment	NOUN
clinmedi-182	22	26	in	in	ADP
clinmedi-182	22	27	traditional	traditional	ADJ
clinmedi-182	22	28	chinese	chinese	ADJ
clinmedi-182	22	29	and	and	CCONJ
clinmedi-182	22	30	ayurvedic	ayurvedic	ADJ
clinmedi-182	22	31	medicine	medicine	NOUN
clinmedi-182	22	32	[	[	X
clinmedi-182	22	33	4	4	NUM
clinmedi-182	22	34	]	]	PUNCT
clinmedi-182	22	35	.	.	PUNCT
clinmedi-182	23	1	it	it	PRON
clinmedi-182	23	2	regulates	regulate	VERB
clinmedi-182	23	3	various	various	ADJ
clinmedi-182	23	4	biochemical	biochemical	ADJ
clinmedi-182	23	5	and	and	CCONJ
clinmedi-182	23	6	molecular	molecular	ADJ
clinmedi-182	23	7	pathways	pathway	NOUN
clinmedi-182	23	8	by	by	ADP
clinmedi-182	23	9	modulating	modulate	VERB
clinmedi-182	23	10	several	several	ADJ
clinmedi-182	23	11	molecular	molecular	ADJ
clinmedi-182	23	12	targets	target	NOUN
clinmedi-182	23	13	,	,	PUNCT
clinmedi-182	23	14	including	include	VERB
clinmedi-182	23	15	transcription	transcription	NOUN
clinmedi-182	23	16	factors	factor	NOUN
clinmedi-182	23	17	,	,	PUNCT
clinmedi-182	23	18	cytokines	cytokine	NOUN
clinmedi-182	23	19	,	,	PUNCT
clinmedi-182	23	20	enzymes	enzyme	NOUN
clinmedi-182	23	21	,	,	PUNCT
clinmedi-182	23	22	and	and	CCONJ
clinmedi-182	23	23	genes	gene	NOUN
clinmedi-182	23	24	,	,	PUNCT
clinmedi-182	23	25	that	that	PRON
clinmedi-182	23	26	regulate	regulate	VERB
clinmedi-182	23	27	cell	cell	NOUN
clinmedi-182	23	28	proliferation	proliferation	NOUN
clinmedi-182	23	29	or	or	CCONJ
clinmedi-182	23	30	apoptosis	apoptosis	NOUN
clinmedi-182	23	31	[	[	X
clinmedi-182	23	32	5	5	NUM
clinmedi-182	23	33	]	]	PUNCT
clinmedi-182	23	34	.	.	PUNCT
clinmedi-182	24	1	it	it	PRON
clinmedi-182	24	2	appears	appear	VERB
clinmedi-182	24	3	to	to	PART
clinmedi-182	24	4	have	have	VERB
clinmedi-182	24	5	anti	anti	ADJ
clinmedi-182	24	6	-	-	ADJ
clinmedi-182	24	7	inflammatory	inflammatory	ADJ
clinmedi-182	24	8	effects	effect	NOUN
clinmedi-182	24	9	comparable	comparable	ADJ
clinmedi-182	24	10	to	to	ADP
clinmedi-182	24	11	steroidal	steroidal	NOUN
clinmedi-182	24	12	drugs	drug	NOUN
clinmedi-182	24	13	and	and	CCONJ
clinmedi-182	24	14	nsaids	nsaid	NOUN
clinmedi-182	24	15	such	such	ADJ
clinmedi-182	24	16	as	as	ADP
clinmedi-182	24	17	indomethacin	indomethacin	NOUN
clinmedi-182	24	18	and	and	CCONJ
clinmedi-182	24	19	phenylbutazone	phenylbutazone	NOUN
clinmedi-182	24	20	[	[	X
clinmedi-182	24	21	6	6	NUM
clinmedi-182	24	22	]	]	PUNCT
clinmedi-182	24	23	.	.	PUNCT
clinmedi-182	25	1	some	some	DET
clinmedi-182	25	2	studies	study	NOUN
clinmedi-182	25	3	have	have	AUX
clinmedi-182	25	4	linked	link	VERB
clinmedi-182	25	5	curcumin	curcumin	NOUN
clinmedi-182	25	6	’s	’s	PART
clinmedi-182	25	7	anti	anti	ADJ
clinmedi-182	25	8	-	-	ADJ
clinmedi-182	25	9	inflammatory	inflammatory	ADJ
clinmedi-182	25	10	properties	property	NOUN
clinmedi-182	25	11	to	to	ADP
clinmedi-182	25	12	the	the	DET
clinmedi-182	25	13	suppression	suppression	NOUN
clinmedi-182	25	14	of	of	ADP
clinmedi-182	25	15	prostaglandin	prostaglandin	VERB
clinmedi-182	25	16	synthesis	synthesis	NOUN
clinmedi-182	25	17	by	by	ADP
clinmedi-182	25	18	its	its	PRON
clinmedi-182	25	19	effect	effect	NOUN
clinmedi-182	25	20	on	on	ADP
clinmedi-182	25	21	cyclooxygenase	cyclooxygenase	NOUN
clinmedi-182	25	22	[	[	X
clinmedi-182	25	23	7	7	NUM
clinmedi-182	25	24	]	]	PUNCT
clinmedi-182	25	25	,	,	PUNCT
clinmedi-182	25	26	a	a	DET
clinmedi-182	25	27	key	key	ADJ
clinmedi-182	25	28	enzyme	enzyme	NOUN
clinmedi-182	25	29	responsible	responsible	ADJ
clinmedi-182	25	30	for	for	ADP
clinmedi-182	25	31	the	the	DET
clinmedi-182	25	32	conversion	conversion	NOUN
clinmedi-182	25	33	of	of	ADP
clinmedi-182	25	34	arachidonic	arachidonic	ADJ
clinmedi-182	25	35	acid	acid	NOUN
clinmedi-182	25	36	to	to	ADP
clinmedi-182	25	37	prostaglandins	prostaglandin	NOUN
clinmedi-182	25	38	.	.	PUNCT
clinmedi-182	26	1	it	it	PRON
clinmedi-182	26	2	has	have	AUX
clinmedi-182	26	3	also	also	ADV
clinmedi-182	26	4	been	be	AUX
clinmedi-182	26	5	shown	show	VERB
clinmedi-182	26	6	to	to	PART
clinmedi-182	26	7	inhibit	inhibit	VERB
clinmedi-182	26	8	proteasome	proteasome	NOUN
clinmedi-182	26	9	activity	activity	NOUN
clinmedi-182	26	10	and	and	CCONJ
clinmedi-182	26	11	induce	induce	VERB
clinmedi-182	26	12	apoptosis	apoptosis	NOUN
clinmedi-182	26	13	in	in	ADP
clinmedi-182	26	14	human	human	ADJ
clinmedi-182	26	15	colon	colon	NOUN
clinmedi-182	26	16	cancer	cancer	NOUN
clinmedi-182	26	17	cells	cell	NOUN
clinmedi-182	26	18	,	,	PUNCT
clinmedi-182	26	19	both	both	CCONJ
clinmedi-182	26	20	in	in	ADP
clinmedi-182	26	21	vitro	vitro	X
clinmedi-182	26	22	and	and	CCONJ
clinmedi-182	26	23	in	in	ADP
clinmedi-182	26	24	vivo	vivo	NOUN
clinmedi-182	26	25	[	[	X
clinmedi-182	26	26	8	8	NUM
clinmedi-182	26	27	]	]	PUNCT
clinmedi-182	26	28	.	.	PUNCT
clinmedi-182	27	1	furthermore	furthermore	ADV
clinmedi-182	27	2	,	,	PUNCT
clinmedi-182	27	3	it	it	PRON
clinmedi-182	27	4	inhibits	inhibit	VERB
clinmedi-182	27	5	nuclear	nuclear	ADJ
clinmedi-182	27	6	factor	factor	NOUN
clinmedi-182	27	7	-	-	PUNCT
clinmedi-182	27	8	kappa	kappa	PROPN
clinmedi-182	27	9	b	b	PROPN
clinmedi-182	27	10	(	(	PUNCT
clinmedi-182	27	11	nf	nf	PROPN
clinmedi-182	27	12	-	-	PUNCT
clinmedi-182	27	13	kb	kb	NOUN
clinmedi-182	27	14	)	)	PUNCT
clinmedi-182	27	15	activation	activation	NOUN
clinmedi-182	27	16	[	[	X
clinmedi-182	27	17	9	9	NUM
clinmedi-182	27	18	]	]	PUNCT
clinmedi-182	27	19	,	,	PUNCT
clinmedi-182	27	20	which	which	PRON
clinmedi-182	27	21	is	be	AUX
clinmedi-182	27	22	a	a	DET
clinmedi-182	27	23	key	key	ADJ
clinmedi-182	27	24	event	event	NOUN
clinmedi-182	27	25	in	in	ADP
clinmedi-182	27	26	the	the	DET
clinmedi-182	27	27	chronic	chronic	ADJ
clinmedi-182	27	28	inflammatory	inflammatory	ADJ
clinmedi-182	27	29	process	process	NOUN
clinmedi-182	27	30	.	.	PUNCT
clinmedi-182	28	1	based	base	VERB
clinmedi-182	28	2	on	on	ADP
clinmedi-182	28	3	these	these	DET
clinmedi-182	28	4	findings	finding	NOUN
clinmedi-182	28	5	,	,	PUNCT
clinmedi-182	28	6	curcumin	curcumin	NOUN
clinmedi-182	28	7	is	be	AUX
clinmedi-182	28	8	expected	expect	VERB
clinmedi-182	28	9	to	to	PART
clinmedi-182	28	10	be	be	AUX
clinmedi-182	28	11	effective	effective	ADJ
clinmedi-182	28	12	for	for	ADP
clinmedi-182	28	13	a	a	DET
clinmedi-182	28	14	wide	wide	ADJ
clinmedi-182	28	15	range	range	NOUN
clinmedi-182	28	16	of	of	ADP
clinmedi-182	28	17	diseases	disease	NOUN
clinmedi-182	28	18	related	relate	VERB
clinmedi-182	28	19	to	to	ADP
clinmedi-182	28	20	chronic	chronic	ADJ
clinmedi-182	28	21	inflammation	inflammation	NOUN
clinmedi-182	28	22	,	,	PUNCT
clinmedi-182	28	23	including	include	VERB
clinmedi-182	28	24	cancer	cancer	NOUN
clinmedi-182	28	25	,	,	PUNCT
clinmedi-182	28	26	cardiovascular	cardiovascular	ADJ
clinmedi-182	28	27	disease	disease	NOUN
clinmedi-182	28	28	,	,	PUNCT
clinmedi-182	28	29	metabolic	metabolic	NOUN
clinmedi-182	28	30	syndrome	syndrome	NOUN
clinmedi-182	28	31	,	,	PUNCT
clinmedi-182	28	32	alzheimer	alzheimer	PROPN
clinmedi-182	28	33	’s	’s	PART
clinmedi-182	28	34	disease	disease	NOUN
clinmedi-182	28	35	,	,	PUNCT
clinmedi-182	28	36	oa	oa	INTJ
clinmedi-182	28	37	,	,	PUNCT
clinmedi-182	28	38	and	and	CCONJ
clinmedi-182	28	39	other	other	ADJ
clinmedi-182	28	40	common	common	ADJ
clinmedi-182	28	41	diseases	disease	NOUN
clinmedi-182	28	42	and	and	CCONJ
clinmedi-182	28	43	aging	age	VERB
clinmedi-182	28	44	conditions	condition	NOUN
clinmedi-182	28	45	[	[	X
clinmedi-182	28	46	4,5,10,11	4,5,10,11	NOUN
clinmedi-182	28	47	]	]	PUNCT
clinmedi-182	28	48	.	.	PUNCT
clinmedi-182	29	1	furthermore	furthermore	ADV
clinmedi-182	29	2	,	,	PUNCT
clinmedi-182	29	3	it	it	PRON
clinmedi-182	29	4	has	have	AUX
clinmedi-182	29	5	been	be	AUX
clinmedi-182	29	6	shown	show	VERB
clinmedi-182	29	7	to	to	PART
clinmedi-182	29	8	be	be	AUX
clinmedi-182	29	9	a	a	DET
clinmedi-182	29	10	potent	potent	ADJ
clinmedi-182	29	11	inhibitor	inhibitor	NOUN
clinmedi-182	29	12	of	of	ADP
clinmedi-182	29	13	the	the	DET
clinmedi-182	29	14	chondrocyte	chondrocyte	NOUN
clinmedi-182	29	15	production	production	NOUN
clinmedi-182	29	16	of	of	ADP
clinmedi-182	29	17	inflammatory	inflammatory	ADJ
clinmedi-182	29	18	and	and	CCONJ
clinmedi-182	29	19	catabolic	catabolic	ADJ
clinmedi-182	29	20	mediators	mediator	NOUN
clinmedi-182	29	21	[	[	X
clinmedi-182	29	22	10	10	NUM
clinmedi-182	29	23	]	]	PUNCT
clinmedi-182	29	24	.	.	PUNCT
clinmedi-182	30	1	however	however	ADV
clinmedi-182	30	2	,	,	PUNCT
clinmedi-182	30	3	curcumin	curcumin	PROPN
clinmedi-182	30	4	has	have	VERB
clinmedi-182	30	5	a	a	DET
clinmedi-182	30	6	very	very	ADV
clinmedi-182	30	7	low	low	ADJ
clinmedi-182	30	8	bioavailability	bioavailability	NOUN
clinmedi-182	30	9	.	.	PUNCT
clinmedi-182	31	1	theracurmin	theracurmin	PROPN
clinmedi-182	31	2	○	○	PROPN
clinmedi-182	31	3	r	r	PROPN
clinmedi-182	31	4	,	,	PUNCT
clinmedi-182	31	5	which	which	PRON
clinmedi-182	31	6	is	be	AUX
clinmedi-182	31	7	a	a	DET
clinmedi-182	31	8	submicron	submicron	NOUN
clinmedi-182	31	9	-	-	PUNCT
clinmedi-182	31	10	particle	particle	NOUN
clinmedi-182	31	11	colloidal	colloidal	NOUN
clinmedi-182	31	12	dispersion	dispersion	NOUN
clinmedi-182	31	13	of	of	ADP
clinmedi-182	31	14	curcumin	curcumin	NOUN
clinmedi-182	32	1	[	[	X
clinmedi-182	32	2	12	12	NUM
clinmedi-182	32	3	]	]	PUNCT
clinmedi-182	32	4	,	,	PUNCT
clinmedi-182	32	5	has	have	VERB
clinmedi-182	32	6	better	well	ADJ
clinmedi-182	32	7	oral	oral	ADJ
clinmedi-182	32	8	bioavailability	bioavailability	NOUN
clinmedi-182	32	9	in	in	ADP
clinmedi-182	32	10	humans	human	NOUN
clinmedi-182	32	11	[	[	X
clinmedi-182	32	12	13	13	NUM
clinmedi-182	32	13	]	]	PUNCT
clinmedi-182	32	14	.	.	PUNCT
clinmedi-182	33	1	in	in	ADP
clinmedi-182	33	2	a	a	DET
clinmedi-182	33	3	randomized	randomized	ADJ
clinmedi-182	33	4	,	,	PUNCT
clinmedi-182	33	5	double	double	ADJ
clinmedi-182	33	6	-	-	PUNCT
clinmedi-182	33	7	blind	blind	ADJ
clinmedi-182	33	8	,	,	PUNCT
clinmedi-182	33	9	placebo	placebo	NOUN
clinmedi-182	33	10	-	-	PUNCT
clinmedi-182	33	11	controlled	control	VERB
clinmedi-182	33	12	,	,	PUNCT
clinmedi-182	33	13	prospective	prospective	ADJ
clinmedi-182	33	14	clinical	clinical	ADJ
clinmedi-182	33	15	trial	trial	NOUN
clinmedi-182	33	16	in	in	ADP
clinmedi-182	33	17	patients	patient	NOUN
clinmedi-182	33	18	with	with	ADP
clinmedi-182	33	19	oa	oa	PRON
clinmedi-182	33	20	to	to	PART
clinmedi-182	33	21	evaluate	evaluate	VERB
clinmedi-182	33	22	the	the	DET
clinmedi-182	33	23	efficacy	efficacy	NOUN
clinmedi-182	33	24	of	of	ADP
clinmedi-182	33	25	theracurmin	theracurmin	PROPN
clinmedi-182	33	26	○	○	PROPN
clinmedi-182	33	27	r	r	PROPN
clinmedi-182	33	28	,	,	PUNCT
clinmedi-182	33	29	,	,	PUNCT
clinmedi-182	33	30	nakagawa	nakagawa	PROPN
clinmedi-182	33	31	showed	show	VERB
clinmedi-182	33	32	that	that	SCONJ
clinmedi-182	33	33	theracurmin	theracurmin	NOUN
clinmedi-182	33	34	○	○	PROPN
clinmedi-182	33	35	r	r	NOUN
clinmedi-182	33	36	improved	improve	VERB
clinmedi-182	33	37	the	the	DET
clinmedi-182	33	38	knee	knee	NOUN
clinmedi-182	33	39	pain	pain	NOUN
clinmedi-182	33	40	visual	visual	ADJ
clinmedi-182	33	41	analog	analog	NOUN
clinmedi-182	33	42	scale	scale	NOUN
clinmedi-182	33	43	(	(	PUNCT
clinmedi-182	33	44	vas	vas	NOUN
clinmedi-182	33	45	)	)	PUNCT
clinmedi-182	33	46	scores	score	NOUN
clinmedi-182	33	47	[	[	X
clinmedi-182	33	48	14	14	NUM
clinmedi-182	33	49	]	]	PUNCT
clinmedi-182	33	50	.	.	PUNCT
clinmedi-182	34	1	to	to	PART
clinmedi-182	34	2	further	far	ADV
clinmedi-182	34	3	improve	improve	VERB
clinmedi-182	34	4	bioavailability	bioavailability	NOUN
clinmedi-182	34	5	,	,	PUNCT
clinmedi-182	34	6	sunagawa	sunagawa	PROPN
clinmedi-182	34	7	developed	develop	VERB
clinmedi-182	34	8	curcurouge	curcurouge	NOUN
clinmedi-182	34	9	○	○	PROPN
clinmedi-182	34	10	r(therabiopharma	r(therabiopharma	NOUN
clinmedi-182	34	11	,	,	PUNCT
clinmedi-182	34	12	kanagawa	kanagawa	PROPN
clinmedi-182	34	13	,	,	PUNCT
clinmedi-182	34	14	japan	japan	PROPN
clinmedi-182	34	15	)	)	PUNCT
clinmedi-182	34	16	,	,	PUNCT
clinmedi-182	34	17	a	a	DET
clinmedi-182	34	18	novel	novel	ADJ
clinmedi-182	34	19	amorphous	amorphous	ADJ
clinmedi-182	34	20	formulation	formulation	NOUN
clinmedi-182	34	21	of	of	ADP
clinmedi-182	34	22	curcumin	curcumin	NOUN
clinmedi-182	34	23	.	.	PUNCT
clinmedi-182	35	1	they	they	PRON
clinmedi-182	35	2	confirmed	confirm	VERB
clinmedi-182	35	3	that	that	SCONJ
clinmedi-182	35	4	curcurouge	curcurouge	NOUN
clinmedi-182	35	5	○	○	PROPN
clinmedi-182	35	6	r	r	NOUN
clinmedi-182	35	7	was	be	AUX
clinmedi-182	35	8	3.4	3.4	NUM
clinmedi-182	35	9	-	-	ADJ
clinmedi-182	35	10	fold	fold	VERB
clinmedi-182	35	11	higher	high	ADJ
clinmedi-182	35	12	bioavailable	bioavailable	ADJ
clinmedi-182	35	13	than	than	ADP
clinmedi-182	35	14	theacurmin	theacurmin	ADJ
clinmedi-182	35	15	○	○	PROPN
clinmedi-182	35	16	r	r	NOUN
clinmedi-182	35	17	in	in	ADP
clinmedi-182	35	18	a	a	DET
clinmedi-182	35	19	single	single	ADJ
clinmedi-182	35	20	-	-	PUNCT
clinmedi-182	35	21	dose	dose	NOUN
clinmedi-182	35	22	,	,	PUNCT
clinmedi-182	35	23	double	double	ADJ
clinmedi-182	35	24	-	-	PUNCT
clinmedi-182	35	25	blind	blind	ADJ
clinmedi-182	35	26	,	,	PUNCT
clinmedi-182	35	27	two	two	NUM
clinmedi-182	35	28	-	-	PUNCT
clinmedi-182	35	29	way	way	NOUN
clinmedi-182	35	30	crossover	crossover	NOUN
clinmedi-182	35	31	study	study	NOUN
clinmedi-182	35	32	in	in	ADP
clinmedi-182	35	33	12	12	NUM
clinmedi-182	35	34	volunteers	volunteer	NOUN
clinmedi-182	35	35	[	[	X
clinmedi-182	35	36	15	15	NUM
clinmedi-182	35	37	]	]	PUNCT
clinmedi-182	35	38	.	.	PUNCT
clinmedi-182	36	1	the	the	DET
clinmedi-182	36	2	purpose	purpose	NOUN
clinmedi-182	36	3	of	of	ADP
clinmedi-182	36	4	the	the	DET
clinmedi-182	36	5	current	current	ADJ
clinmedi-182	36	6	study	study	NOUN
clinmedi-182	36	7	was	be	AUX
clinmedi-182	36	8	to	to	PART
clinmedi-182	36	9	determine	determine	VERB
clinmedi-182	36	10	the	the	DET
clinmedi-182	36	11	clinical	clinical	ADJ
clinmedi-182	36	12	efficacy	efficacy	NOUN
clinmedi-182	36	13	of	of	ADP
clinmedi-182	36	14	orally	orally	ADV
clinmedi-182	36	15	administered	administer	VERB
clinmedi-182	36	16	curcurouge	curcurouge	NOUN
clinmedi-182	36	17	○	○	PROPN
clinmedi-182	36	18	r	r	NOUN
clinmedi-182	36	19	in	in	ADP
clinmedi-182	36	20	patients	patient	NOUN
clinmedi-182	36	21	with	with	ADP
clinmedi-182	36	22	knee	knee	NOUN
clinmedi-182	36	23	oa	oa	NOUN
clinmedi-182	36	24	after	after	ADP
clinmedi-182	36	25	12	12	NUM
clinmedi-182	36	26	weeks	week	NOUN
clinmedi-182	36	27	of	of	ADP
clinmedi-182	36	28	treatment	treatment	NOUN
clinmedi-182	36	29	.	.	PUNCT
clinmedi-182	37	1	we	we	PRON
clinmedi-182	37	2	hypothesized	hypothesize	VERB
clinmedi-182	37	3	that	that	SCONJ
clinmedi-182	37	4	consuming	consume	VERB
clinmedi-182	37	5	curcurouge	curcurouge	NOUN
clinmedi-182	37	6	○	○	PROPN
clinmedi-182	37	7	r	r	NOUN
clinmedi-182	37	8	ingestion	ingestion	NOUN
clinmedi-182	37	9	for	for	ADP
clinmedi-182	37	10	12	12	NUM
clinmedi-182	37	11	weeks	week	NOUN
clinmedi-182	37	12	would	would	AUX
clinmedi-182	37	13	improve	improve	VERB
clinmedi-182	37	14	the	the	DET
clinmedi-182	37	15	symptoms	symptom	NOUN
clinmedi-182	37	16	and	and	CCONJ
clinmedi-182	37	17	functional	functional	ADJ
clinmedi-182	37	18	abilities	ability	NOUN
clinmedi-182	37	19	of	of	ADP
clinmedi-182	37	20	patients	patient	NOUN
clinmedi-182	37	21	with	with	ADP
clinmedi-182	37	22	knee	knee	NOUN
clinmedi-182	37	23	oa	oa	INTJ
clinmedi-182	37	24	.	.	PUNCT
clinmedi-182	37	25	materials	material	NOUN
clinmedi-182	37	26	and	and	CCONJ
clinmedi-182	37	27	methods	method	NOUN
clinmedi-182	37	28	to	to	PART
clinmedi-182	37	29	test	test	VERB
clinmedi-182	37	30	our	our	PRON
clinmedi-182	37	31	hypothesis	hypothesis	NOUN
clinmedi-182	37	32	,	,	PUNCT
clinmedi-182	37	33	we	we	PRON
clinmedi-182	37	34	conducted	conduct	VERB
clinmedi-182	37	35	a	a	DET
clinmedi-182	37	36	randomized	randomized	ADJ
clinmedi-182	37	37	,	,	PUNCT
clinmedi-182	37	38	double	double	ADJ
clinmedi-182	37	39	-	-	PUNCT
clinmedi-182	37	40	blind	blind	ADJ
clinmedi-182	37	41	,	,	PUNCT
clinmedi-182	37	42	placebo	placebo	NOUN
clinmedi-182	37	43	-	-	PUNCT
clinmedi-182	37	44	controlled	control	VERB
clinmedi-182	37	45	,	,	PUNCT
clinmedi-182	37	46	prospective	prospective	ADJ
clinmedi-182	37	47	clinical	clinical	ADJ
clinmedi-182	37	48	study	study	NOUN
clinmedi-182	37	49	with	with	ADP
clinmedi-182	37	50	three	three	NUM
clinmedi-182	37	51	treatment	treatment	NOUN
clinmedi-182	37	52	groups	group	NOUN
clinmedi-182	37	53	:	:	PUNCT
clinmedi-182	37	54	high	high	ADJ
clinmedi-182	37	55	dose	dose	PROPN
clinmedi-182	37	56	(	(	PUNCT
clinmedi-182	37	57	180	180	NUM
clinmedi-182	37	58	mg	mg	NUM
clinmedi-182	37	59	/	/	SYM
clinmedi-182	37	60	day	day	NOUN
clinmedi-182	37	61	curcumin	curcumin	NOUN
clinmedi-182	37	62	)	)	PUNCT
clinmedi-182	37	63	and	and	CCONJ
clinmedi-182	37	64	low	low	ADJ
clinmedi-182	37	65	dose	dose	NOUN
clinmedi-182	37	66	(	(	PUNCT
clinmedi-182	37	67	60	60	NUM
clinmedi-182	37	68	mg	mg	NUM
clinmedi-182	37	69	/	/	SYM
clinmedi-182	37	70	day	day	NOUN
clinmedi-182	37	71	curcumin	curcumin	NOUN
clinmedi-182	37	72	)	)	PUNCT
clinmedi-182	37	73	curcurouge	curcurouge	NOUN
clinmedi-182	37	74	○	○	PROPN
clinmedi-182	37	75	r	r	NOUN
clinmedi-182	37	76	and	and	CCONJ
clinmedi-182	37	77	placebo	placebo	NOUN
clinmedi-182	37	78	.	.	PUNCT
clinmedi-182	38	1	at	at	ADP
clinmedi-182	38	2	the	the	DET
clinmedi-182	38	3	start	start	NOUN
clinmedi-182	38	4	of	of	ADP
clinmedi-182	38	5	the	the	DET
clinmedi-182	38	6	treatment	treatment	NOUN
clinmedi-182	38	7	period	period	NOUN
clinmedi-182	38	8	,	,	PUNCT
clinmedi-182	38	9	randomization	randomization	NOUN
clinmedi-182	38	10	was	be	AUX
clinmedi-182	38	11	cmi	cmi	NOUN
clinmedi-182	38	12	04	04	NUM
clinmedi-182	38	13	(	(	PUNCT
clinmedi-182	38	14	03	03	NUM
clinmedi-182	38	15	)	)	PUNCT
clinmedi-182	38	16	,	,	PUNCT
clinmedi-182	38	17	415−429	415−429	PROPN
clinmedi-182	38	18	cmi	cmi	PROPN
clinmedi-182	38	19	journal	journal	PROPN
clinmedi-182	38	20	417	417	NUM
clinmedi-182	38	21	cmi	cmi	PROPN
clinmedi-182	38	22	journal	journal	PROPN
clinmedi-182	38	23	yasuaki	yasuaki	PROPN
clinmedi-182	38	24	nakagawa	nakagawa	PROPN
clinmedi-182	38	25	,	,	PUNCT
clinmedi-182	38	26	md	md	PROPN
clinmedi-182	38	27	performed	perform	VERB
clinmedi-182	38	28	after	after	ADP
clinmedi-182	38	29	baseline	baseline	NOUN
clinmedi-182	38	30	tests	test	NOUN
clinmedi-182	38	31	and	and	CCONJ
clinmedi-182	38	32	using	use	VERB
clinmedi-182	38	33	a	a	DET
clinmedi-182	38	34	computer	computer	NOUN
clinmedi-182	38	35	-	-	PUNCT
clinmedi-182	38	36	generated	generate	VERB
clinmedi-182	38	37	numbers	number	NOUN
clinmedi-182	38	38	table	table	NOUN
clinmedi-182	38	39	without	without	ADP
clinmedi-182	38	40	stratification	stratification	NOUN
clinmedi-182	38	41	.	.	PUNCT
clinmedi-182	39	1	based	base	VERB
clinmedi-182	39	2	on	on	ADP
clinmedi-182	39	3	randomization	randomization	NOUN
clinmedi-182	39	4	,	,	PUNCT
clinmedi-182	39	5	the	the	DET
clinmedi-182	39	6	allocation	allocation	NOUN
clinmedi-182	39	7	was	be	AUX
clinmedi-182	39	8	performed	perform	VERB
clinmedi-182	39	9	by	by	ADP
clinmedi-182	39	10	someone	someone	PRON
clinmedi-182	39	11	who	who	PRON
clinmedi-182	39	12	was	be	AUX
clinmedi-182	39	13	not	not	PART
clinmedi-182	39	14	involved	involve	VERB
clinmedi-182	39	15	in	in	ADP
clinmedi-182	39	16	the	the	DET
clinmedi-182	39	17	current	current	ADJ
clinmedi-182	39	18	project	project	NOUN
clinmedi-182	39	19	.	.	PUNCT
clinmedi-182	40	1	from	from	ADP
clinmedi-182	40	2	september	september	PROPN
clinmedi-182	40	3	2020	2020	NUM
clinmedi-182	40	4	to	to	ADP
clinmedi-182	40	5	october	october	PROPN
clinmedi-182	40	6	2022	2022	NUM
clinmedi-182	40	7	,	,	PUNCT
clinmedi-182	40	8	90	90	NUM
clinmedi-182	40	9	patients	patient	NOUN
clinmedi-182	40	10	over	over	ADP
clinmedi-182	40	11	the	the	DET
clinmedi-182	40	12	age	age	NOUN
clinmedi-182	40	13	of	of	ADP
clinmedi-182	40	14	40	40	NUM
clinmedi-182	40	15	with	with	ADP
clinmedi-182	40	16	knee	knee	NOUN
clinmedi-182	40	17	oa	oa	PROPN
clinmedi-182	40	18	confirmed	confirm	VERB
clinmedi-182	40	19	by	by	ADP
clinmedi-182	40	20	the	the	DET
clinmedi-182	40	21	radiographic	radiographic	ADJ
clinmedi-182	40	22	analysis	analysis	NOUN
clinmedi-182	40	23	were	be	AUX
clinmedi-182	40	24	selected	select	VERB
clinmedi-182	40	25	and	and	CCONJ
clinmedi-182	40	26	enrolled	enrol	VERB
clinmedi-182	40	27	in	in	ADP
clinmedi-182	40	28	the	the	DET
clinmedi-182	40	29	study	study	NOUN
clinmedi-182	40	30	.	.	PUNCT
clinmedi-182	41	1	they	they	PRON
clinmedi-182	41	2	were	be	AUX
clinmedi-182	41	3	divided	divide	VERB
clinmedi-182	41	4	into	into	ADP
clinmedi-182	41	5	three	three	NUM
clinmedi-182	41	6	groups	group	NOUN
clinmedi-182	41	7	of	of	ADP
clinmedi-182	41	8	30	30	NUM
clinmedi-182	41	9	patients	patient	NOUN
clinmedi-182	41	10	each	each	PRON
clinmedi-182	41	11	.	.	PUNCT
clinmedi-182	42	1	before	before	ADP
clinmedi-182	42	2	participating	participate	VERB
clinmedi-182	42	3	,	,	PUNCT
clinmedi-182	42	4	all	all	DET
clinmedi-182	42	5	subjects	subject	NOUN
clinmedi-182	42	6	provided	provide	VERB
clinmedi-182	42	7	written	write	VERB
clinmedi-182	42	8	informed	inform	VERB
clinmedi-182	42	9	consent	consent	NOUN
clinmedi-182	42	10	.	.	PUNCT
clinmedi-182	43	1	all	all	DET
clinmedi-182	43	2	procedures	procedure	NOUN
clinmedi-182	43	3	were	be	AUX
clinmedi-182	43	4	reviewed	review	VERB
clinmedi-182	43	5	and	and	CCONJ
clinmedi-182	43	6	approved	approve	VERB
clinmedi-182	43	7	by	by	ADP
clinmedi-182	43	8	the	the	DET
clinmedi-182	43	9	nara	nara	PROPN
clinmedi-182	43	10	medical	medical	PROPN
clinmedi-182	43	11	university	university	PROPN
clinmedi-182	43	12	certified	certify	VERB
clinmedi-182	43	13	review	review	NOUN
clinmedi-182	43	14	board	board	NOUN
clinmedi-182	43	15	(	(	PUNCT
clinmedi-182	43	16	nara0017	nara0017	PROPN
clinmedi-182	43	17	)	)	PUNCT
clinmedi-182	43	18	,	,	PUNCT
clinmedi-182	43	19	and	and	CCONJ
clinmedi-182	43	20	this	this	DET
clinmedi-182	43	21	study	study	NOUN
clinmedi-182	43	22	was	be	AUX
clinmedi-182	43	23	performed	perform	VERB
clinmedi-182	43	24	in	in	ADP
clinmedi-182	43	25	accordance	accordance	NOUN
clinmedi-182	43	26	with	with	ADP
clinmedi-182	43	27	the	the	DET
clinmedi-182	43	28	world	world	PROPN
clinmedi-182	43	29	medical	medical	PROPN
clinmedi-182	43	30	association	association	PROPN
clinmedi-182	43	31	’s	’s	PART
clinmedi-182	43	32	declaration	declaration	NOUN
clinmedi-182	43	33	of	of	ADP
clinmedi-182	43	34	helsinki	helsinki	PROPN
clinmedi-182	43	35	.	.	PUNCT
clinmedi-182	44	1	this	this	DET
clinmedi-182	44	2	study	study	NOUN
clinmedi-182	44	3	was	be	AUX
clinmedi-182	44	4	registered	register	VERB
clinmedi-182	44	5	at	at	ADP
clinmedi-182	44	6	japan	japan	PROPN
clinmedi-182	44	7	registry	registry	PROPN
clinmedi-182	44	8	for	for	ADP
clinmedi-182	44	9	clinical	clinical	ADJ
clinmedi-182	44	10	trials	trial	NOUN
clinmedi-182	44	11	(	(	PUNCT
clinmedi-182	44	12	jrcts051200058	jrcts051200058	PROPN
clinmedi-182	44	13	)	)	PUNCT
clinmedi-182	44	14	.	.	PUNCT
clinmedi-182	45	1	in	in	ADP
clinmedi-182	45	2	this	this	DET
clinmedi-182	45	3	study	study	NOUN
clinmedi-182	45	4	,	,	PUNCT
clinmedi-182	45	5	patients	patient	NOUN
clinmedi-182	45	6	over	over	ADP
clinmedi-182	45	7	the	the	DET
clinmedi-182	45	8	age	age	NOUN
clinmedi-182	45	9	of	of	ADP
clinmedi-182	45	10	40	40	NUM
clinmedi-182	45	11	with	with	ADP
clinmedi-182	45	12	primary	primary	ADJ
clinmedi-182	45	13	medial	medial	ADJ
clinmedi-182	45	14	knee	knee	NOUN
clinmedi-182	45	15	oa	oa	NOUN
clinmedi-182	45	16	and	and	CCONJ
clinmedi-182	45	17	kl	kl	PROPN
clinmedi-182	45	18	grades	grade	NOUN
clinmedi-182	45	19	of	of	ADP
clinmedi-182	45	20	ii	ii	PROPN
clinmedi-182	45	21	or	or	CCONJ
clinmedi-182	45	22	iii	iii	NOUN
clinmedi-182	45	23	with	with	ADP
clinmedi-182	45	24	radiographic	radiographic	ADJ
clinmedi-182	45	25	classification	classification	NOUN
clinmedi-182	45	26	were	be	AUX
clinmedi-182	45	27	eligible	eligible	ADJ
clinmedi-182	45	28	.	.	PUNCT
clinmedi-182	46	1	however	however	ADV
clinmedi-182	46	2	,	,	PUNCT
clinmedi-182	46	3	patients	patient	NOUN
clinmedi-182	46	4	with	with	ADP
clinmedi-182	46	5	severe	severe	ADJ
clinmedi-182	46	6	renal	renal	ADJ
clinmedi-182	46	7	dysfunction	dysfunction	NOUN
clinmedi-182	46	8	or	or	CCONJ
clinmedi-182	46	9	on	on	ADP
clinmedi-182	46	10	dialysis	dialysis	NOUN
clinmedi-182	46	11	,	,	PUNCT
clinmedi-182	46	12	severe	severe	ADJ
clinmedi-182	46	13	liver	liver	NOUN
clinmedi-182	46	14	dysfunction	dysfunction	NOUN
clinmedi-182	46	15	or	or	CCONJ
clinmedi-182	46	16	cirrhosis	cirrhosis	NOUN
clinmedi-182	46	17	,	,	PUNCT
clinmedi-182	46	18	severe	severe	ADJ
clinmedi-182	46	19	cardiovascular	cardiovascular	ADJ
clinmedi-182	46	20	diseases	disease	NOUN
clinmedi-182	46	21	,	,	PUNCT
clinmedi-182	46	22	severe	severe	ADJ
clinmedi-182	46	23	cerebrovascular	cerebrovascular	ADJ
clinmedi-182	46	24	dysfunction	dysfunction	NOUN
clinmedi-182	46	25	,	,	PUNCT
clinmedi-182	46	26	severe	severe	ADJ
clinmedi-182	46	27	diabetes	diabetes	NOUN
clinmedi-182	46	28	mellitus	mellitus	NOUN
clinmedi-182	46	29	,	,	PUNCT
clinmedi-182	46	30	curcumin	curcumin	NOUN
clinmedi-182	46	31	abuse	abuse	NOUN
clinmedi-182	46	32	,	,	PUNCT
clinmedi-182	46	33	or	or	CCONJ
clinmedi-182	46	34	pregnancy	pregnancy	NOUN
clinmedi-182	46	35	were	be	AUX
clinmedi-182	46	36	excluded	exclude	VERB
clinmedi-182	46	37	from	from	ADP
clinmedi-182	46	38	this	this	DET
clinmedi-182	46	39	study	study	NOUN
clinmedi-182	46	40	.	.	PUNCT
clinmedi-182	47	1	furthermore	furthermore	ADV
clinmedi-182	47	2	,	,	PUNCT
clinmedi-182	47	3	those	those	PRON
clinmedi-182	47	4	who	who	PRON
clinmedi-182	47	5	had	have	AUX
clinmedi-182	47	6	received	receive	VERB
clinmedi-182	47	7	more	more	ADJ
clinmedi-182	47	8	than	than	ADP
clinmedi-182	47	9	two	two	NUM
clinmedi-182	47	10	types	type	NOUN
clinmedi-182	47	11	of	of	ADP
clinmedi-182	47	12	anticoagulants	anticoagulant	NOUN
clinmedi-182	47	13	,	,	PUNCT
clinmedi-182	47	14	previous	previous	ADJ
clinmedi-182	47	15	knee	knee	NOUN
clinmedi-182	47	16	surgeries	surgery	NOUN
clinmedi-182	47	17	,	,	PUNCT
clinmedi-182	47	18	knee	knee	NOUN
clinmedi-182	47	19	injection	injection	NOUN
clinmedi-182	47	20	treatment	treatment	NOUN
clinmedi-182	47	21	including	include	VERB
clinmedi-182	47	22	hyaluronic	hyaluronic	ADJ
clinmedi-182	47	23	acid	acid	NOUN
clinmedi-182	47	24	during	during	ADP
clinmedi-182	47	25	the	the	DET
clinmedi-182	47	26	study	study	NOUN
clinmedi-182	47	27	,	,	PUNCT
clinmedi-182	47	28	knee	knee	NOUN
clinmedi-182	47	29	steroid	steroid	NOUN
clinmedi-182	47	30	injections	injection	NOUN
clinmedi-182	47	31	two	two	NUM
clinmedi-182	47	32	months	month	NOUN
clinmedi-182	47	33	before	before	ADP
clinmedi-182	47	34	the	the	DET
clinmedi-182	47	35	study	study	NOUN
clinmedi-182	47	36	,	,	PUNCT
clinmedi-182	47	37	or	or	CCONJ
clinmedi-182	47	38	other	other	ADJ
clinmedi-182	47	39	steroids	steroid	NOUN
clinmedi-182	47	40	four	four	NUM
clinmedi-182	47	41	weeks	week	NOUN
clinmedi-182	47	42	before	before	SCONJ
clinmedi-182	47	43	the	the	DET
clinmedi-182	47	44	study	study	NOUN
clinmedi-182	47	45	were	be	AUX
clinmedi-182	47	46	excluded	exclude	VERB
clinmedi-182	47	47	.	.	PUNCT
clinmedi-182	48	1	if	if	SCONJ
clinmedi-182	48	2	patients	patient	NOUN
clinmedi-182	48	3	required	require	VERB
clinmedi-182	48	4	nsaids	nsaid	NOUN
clinmedi-182	48	5	during	during	ADP
clinmedi-182	48	6	the	the	DET
clinmedi-182	48	7	study	study	NOUN
clinmedi-182	48	8	,	,	PUNCT
clinmedi-182	48	9	oral	oral	ADJ
clinmedi-182	48	10	celecoxib	celecoxib	VERB
clinmedi-182	48	11	two	two	NUM
clinmedi-182	48	12	pills	pill	NOUN
clinmedi-182	48	13	per	per	ADP
clinmedi-182	48	14	day	day	NOUN
clinmedi-182	48	15	(	(	PUNCT
clinmedi-182	48	16	100	100	NUM
clinmedi-182	48	17	mg	mg	NOUN
clinmedi-182	48	18	per	per	ADP
clinmedi-182	48	19	pill	pill	NOUN
clinmedi-182	48	20	)	)	PUNCT
clinmedi-182	48	21	were	be	AUX
clinmedi-182	48	22	prescribed	prescribe	VERB
clinmedi-182	48	23	.	.	PUNCT
clinmedi-182	49	1	the	the	DET
clinmedi-182	49	2	other	other	ADJ
clinmedi-182	49	3	combined	combined	ADJ
clinmedi-182	49	4	therapy	therapy	NOUN
clinmedi-182	49	5	we	we	PRON
clinmedi-182	49	6	allowed	allow	VERB
clinmedi-182	49	7	was	be	AUX
clinmedi-182	49	8	pain	pain	NOUN
clinmedi-182	49	9	relief	relief	NOUN
clinmedi-182	49	10	patches	patch	NOUN
clinmedi-182	49	11	.	.	PUNCT
clinmedi-182	50	1	a	a	DET
clinmedi-182	50	2	high	high	ADJ
clinmedi-182	50	3	or	or	CCONJ
clinmedi-182	50	4	low	low	ADV
clinmedi-182	50	5	-	-	PUNCT
clinmedi-182	50	6	dose	dose	NOUN
clinmedi-182	50	7	of	of	ADP
clinmedi-182	50	8	curcurouge	curcurouge	NOUN
clinmedi-182	50	9	○	○	PROPN
clinmedi-182	50	10	r	r	NOUN
clinmedi-182	50	11	or	or	CCONJ
clinmedi-182	50	12	placebo	placebo	NOUN
clinmedi-182	50	13	was	be	AUX
clinmedi-182	50	14	administered	administer	VERB
clinmedi-182	50	15	orally	orally	ADV
clinmedi-182	50	16	twice	twice	DET
clinmedi-182	50	17	a	a	DET
clinmedi-182	50	18	day	day	NOUN
clinmedi-182	50	19	,	,	PUNCT
clinmedi-182	50	20	for	for	ADP
clinmedi-182	50	21	12	12	NUM
clinmedi-182	50	22	weeks	week	NOUN
clinmedi-182	50	23	.	.	PUNCT
clinmedi-182	51	1	patients	patient	NOUN
clinmedi-182	51	2	in	in	ADP
clinmedi-182	51	3	the	the	DET
clinmedi-182	51	4	high	high	ADJ
clinmedi-182	51	5	-	-	PUNCT
clinmedi-182	51	6	dose	dose	NOUN
clinmedi-182	51	7	curcurouge	curcurouge	NOUN
clinmedi-182	51	8	○	○	PROPN
clinmedi-182	51	9	r	r	NOUN
clinmedi-182	51	10	group	group	NOUN
clinmedi-182	51	11	took	take	VERB
clinmedi-182	51	12	two	two	NUM
clinmedi-182	51	13	capsules	capsule	NOUN
clinmedi-182	51	14	containing	contain	VERB
clinmedi-182	51	15	90	90	NUM
clinmedi-182	51	16	mg	mg	NOUN
clinmedi-182	51	17	of	of	ADP
clinmedi-182	51	18	curcumin	curcumin	NOUN
clinmedi-182	51	19	per	per	ADP
clinmedi-182	51	20	capsule	capsule	NOUN
clinmedi-182	51	21	,	,	PUNCT
clinmedi-182	51	22	while	while	SCONJ
clinmedi-182	51	23	those	those	PRON
clinmedi-182	51	24	in	in	ADP
clinmedi-182	51	25	the	the	DET
clinmedi-182	51	26	low	low	ADJ
clinmedi-182	51	27	-	-	PUNCT
clinmedi-182	51	28	dose	dose	NOUN
clinmedi-182	51	29	curcurouge	curcurouge	NOUN
clinmedi-182	51	30	○	○	PROPN
clinmedi-182	51	31	r	r	NOUN
clinmedi-182	51	32	group	group	NOUN
clinmedi-182	51	33	took	take	VERB
clinmedi-182	51	34	two	two	NUM
clinmedi-182	51	35	capsules	capsule	NOUN
clinmedi-182	51	36	containing	contain	VERB
clinmedi-182	51	37	30	30	NUM
clinmedi-182	51	38	mg	mg	NOUN
clinmedi-182	51	39	of	of	ADP
clinmedi-182	51	40	curcumin	curcumin	NOUN
clinmedi-182	51	41	per	per	ADP
clinmedi-182	51	42	capsule	capsule	NOUN
clinmedi-182	51	43	per	per	ADP
clinmedi-182	51	44	day	day	NOUN
clinmedi-182	51	45	.	.	PUNCT
clinmedi-182	52	1	similarly	similarly	ADV
clinmedi-182	52	2	,	,	PUNCT
clinmedi-182	52	3	patients	patient	NOUN
clinmedi-182	52	4	in	in	ADP
clinmedi-182	52	5	the	the	DET
clinmedi-182	52	6	placebo	placebo	NOUN
clinmedi-182	52	7	group	group	NOUN
clinmedi-182	52	8	took	take	VERB
clinmedi-182	52	9	two	two	NUM
clinmedi-182	52	10	placebo	placebo	NOUN
clinmedi-182	52	11	capsules	capsule	NOUN
clinmedi-182	52	12	per	per	ADP
clinmedi-182	52	13	day	day	NOUN
clinmedi-182	52	14	that	that	PRON
clinmedi-182	52	15	were	be	AUX
clinmedi-182	52	16	similar	similar	ADJ
clinmedi-182	52	17	in	in	ADP
clinmedi-182	52	18	shape	shape	NOUN
clinmedi-182	52	19	and	and	CCONJ
clinmedi-182	52	20	color	color	NOUN
clinmedi-182	52	21	to	to	ADP
clinmedi-182	52	22	those	those	PRON
clinmedi-182	52	23	of	of	ADP
clinmedi-182	52	24	curcurouge	curcurouge	NOUN
clinmedi-182	52	25	○	○	NOUN
clinmedi-182	52	26	r	r	NOUN
clinmedi-182	52	27	.	.	PUNCT
clinmedi-182	53	1	the	the	DET
clinmedi-182	53	2	placebo	placebo	NOUN
clinmedi-182	53	3	was	be	AUX
clinmedi-182	53	4	primarily	primarily	ADV
clinmedi-182	53	5	made	make	VERB
clinmedi-182	53	6	of	of	ADP
clinmedi-182	53	7	crystalline	crystalline	ADJ
clinmedi-182	53	8	cellulose	cellulose	NOUN
clinmedi-182	53	9	,	,	PUNCT
clinmedi-182	53	10	silicon	silicon	NOUN
clinmedi-182	53	11	dioxide	dioxide	NOUN
clinmedi-182	53	12	,	,	PUNCT
clinmedi-182	53	13	calcium	calcium	NOUN
clinmedi-182	53	14	stearate	stearate	NOUN
clinmedi-182	53	15	and	and	CCONJ
clinmedi-182	53	16	food	food	NOUN
clinmedi-182	53	17	colorings	coloring	NOUN
clinmedi-182	53	18	.	.	PUNCT
clinmedi-182	54	1	for	for	ADP
clinmedi-182	54	2	the	the	DET
clinmedi-182	54	3	compliance	compliance	NOUN
clinmedi-182	54	4	check	check	NOUN
clinmedi-182	54	5	,	,	PUNCT
clinmedi-182	54	6	the	the	DET
clinmedi-182	54	7	patients	patient	NOUN
clinmedi-182	54	8	were	be	AUX
clinmedi-182	54	9	asked	ask	VERB
clinmedi-182	54	10	to	to	PART
clinmedi-182	54	11	report	report	VERB
clinmedi-182	54	12	the	the	DET
clinmedi-182	54	13	number	number	NOUN
clinmedi-182	54	14	of	of	ADP
clinmedi-182	54	15	remaining	remain	VERB
clinmedi-182	54	16	capsules	capsule	NOUN
clinmedi-182	54	17	and	and	CCONJ
clinmedi-182	54	18	the	the	DET
clinmedi-182	54	19	prescribed	prescribe	VERB
clinmedi-182	54	20	celecoxib	celecoxib	NOUN
clinmedi-182	54	21	pills	pill	NOUN
clinmedi-182	54	22	at	at	ADP
clinmedi-182	54	23	their	their	PRON
clinmedi-182	54	24	2	2	NUM
clinmedi-182	54	25	,	,	PUNCT
clinmedi-182	54	26	4	4	NUM
clinmedi-182	54	27	,	,	PUNCT
clinmedi-182	54	28	6	6	NUM
clinmedi-182	54	29	,	,	PUNCT
clinmedi-182	54	30	8	8	NUM
clinmedi-182	54	31	,	,	PUNCT
clinmedi-182	54	32	10	10	NUM
clinmedi-182	54	33	and	and	CCONJ
clinmedi-182	54	34	12	12	NUM
clinmedi-182	54	35	-	-	PUNCT
clinmedi-182	54	36	week	week	NOUN
clinmedi-182	54	37	visits	visit	NOUN
clinmedi-182	54	38	at	at	ADP
clinmedi-182	54	39	our	our	PRON
clinmedi-182	54	40	outpatient	outpatient	NOUN
clinmedi-182	54	41	clinic	clinic	NOUN
clinmedi-182	54	42	.	.	PUNCT
clinmedi-182	55	1	the	the	DET
clinmedi-182	55	2	study	study	NOUN
clinmedi-182	55	3	’s	’s	PART
clinmedi-182	55	4	flow	flow	NOUN
clinmedi-182	55	5	chart	chart	NOUN
clinmedi-182	55	6	is	be	AUX
clinmedi-182	55	7	depicted	depict	VERB
clinmedi-182	55	8	in	in	ADP
clinmedi-182	55	9	figure	figure	NOUN
clinmedi-182	55	10	1	1	NUM
clinmedi-182	55	11	.	.	PUNCT
clinmedi-182	56	1	the	the	DET
clinmedi-182	56	2	highand	highand	ADJ
clinmedi-182	56	3	low	low	ADJ
clinmedi-182	56	4	-	-	PUNCT
clinmedi-182	56	5	dose	dose	NOUN
clinmedi-182	56	6	curcurouge	curcurouge	NOUN
clinmedi-182	56	7	○	○	PROPN
clinmedi-182	56	8	r	r	NOUN
clinmedi-182	56	9	and	and	CCONJ
clinmedi-182	56	10	placebo	placebo	NOUN
clinmedi-182	56	11	groups	group	NOUN
clinmedi-182	56	12	included	include	VERB
clinmedi-182	56	13	30	30	NUM
clinmedi-182	56	14	patients	patient	NOUN
clinmedi-182	56	15	.	.	PUNCT
clinmedi-182	57	1	the	the	DET
clinmedi-182	57	2	drop	drop	VERB
clinmedi-182	57	3	-	-	PUNCT
clinmedi-182	57	4	out	out	ADP
clinmedi-182	57	5	cases	case	NOUN
clinmedi-182	57	6	due	due	ADJ
clinmedi-182	57	7	to	to	ADP
clinmedi-182	57	8	adverse	adverse	ADJ
clinmedi-182	57	9	events	event	NOUN
clinmedi-182	57	10	were	be	AUX
clinmedi-182	57	11	two	two	NUM
clinmedi-182	57	12	in	in	ADP
clinmedi-182	57	13	the	the	DET
clinmedi-182	57	14	high	high	ADJ
clinmedi-182	57	15	-	-	PUNCT
clinmedi-182	57	16	dose	dose	NOUN
clinmedi-182	57	17	group	group	NOUN
clinmedi-182	57	18	(	(	PUNCT
clinmedi-182	57	19	due	due	ADP
clinmedi-182	57	20	to	to	ADP
clinmedi-182	57	21	severe	severe	ADJ
clinmedi-182	57	22	lumbago	lumbago	NOUN
clinmedi-182	57	23	and	and	CCONJ
clinmedi-182	57	24	buttock	buttock	NOUN
clinmedi-182	57	25	pain	pain	NOUN
clinmedi-182	57	26	in	in	ADP
clinmedi-182	57	27	one	one	NUM
clinmedi-182	57	28	case	case	NOUN
clinmedi-182	57	29	and	and	CCONJ
clinmedi-182	57	30	vertigo	vertigo	NOUN
clinmedi-182	57	31	and	and	CCONJ
clinmedi-182	57	32	nausea	nausea	NOUN
clinmedi-182	57	33	in	in	ADP
clinmedi-182	57	34	one	one	NUM
clinmedi-182	57	35	case	case	NOUN
clinmedi-182	57	36	)	)	PUNCT
clinmedi-182	57	37	,	,	PUNCT
clinmedi-182	57	38	four	four	NUM
clinmedi-182	57	39	in	in	ADP
clinmedi-182	57	40	the	the	DET
clinmedi-182	57	41	low	low	ADJ
clinmedi-182	57	42	-	-	PUNCT
clinmedi-182	57	43	dose	dose	NOUN
clinmedi-182	57	44	group	group	NOUN
clinmedi-182	57	45	(	(	PUNCT
clinmedi-182	57	46	due	due	ADP
clinmedi-182	57	47	to	to	ADP
clinmedi-182	57	48	dermatitis	dermatitis	NOUN
clinmedi-182	57	49	in	in	ADP
clinmedi-182	57	50	one	one	NUM
clinmedi-182	57	51	case	case	NOUN
clinmedi-182	57	52	,	,	PUNCT
clinmedi-182	57	53	consent	consent	NOUN
clinmedi-182	57	54	withdrawal	withdrawal	NOUN
clinmedi-182	57	55	in	in	ADP
clinmedi-182	57	56	one	one	NUM
clinmedi-182	57	57	case	case	NOUN
clinmedi-182	57	58	,	,	PUNCT
clinmedi-182	57	59	severe	severe	ADJ
clinmedi-182	57	60	knee	knee	NOUN
clinmedi-182	57	61	pain	pain	NOUN
clinmedi-182	57	62	in	in	ADP
clinmedi-182	57	63	one	one	NUM
clinmedi-182	57	64	case	case	NOUN
clinmedi-182	57	65	and	and	CCONJ
clinmedi-182	57	66	un	un	NOUN
clinmedi-182	57	67	-	-	NOUN
clinmedi-182	57	68	wellness	wellness	NOUN
clinmedi-182	57	69	in	in	ADP
clinmedi-182	57	70	one	one	NUM
clinmedi-182	57	71	case	case	NOUN
clinmedi-182	57	72	)	)	PUNCT
clinmedi-182	57	73	,	,	PUNCT
clinmedi-182	57	74	and	and	CCONJ
clinmedi-182	57	75	none	none	NOUN
clinmedi-182	57	76	in	in	ADP
clinmedi-182	57	77	the	the	DET
clinmedi-182	57	78	placebo	placebo	NOUN
clinmedi-182	57	79	group	group	NOUN
clinmedi-182	57	80	.	.	PUNCT
clinmedi-182	58	1	the	the	DET
clinmedi-182	58	2	study	study	NOUN
clinmedi-182	58	3	’s	’s	PART
clinmedi-182	58	4	safety	safety	NOUN
clinmedi-182	58	5	committee	committee	PROPN
clinmedi-182	58	6	decided	decide	VERB
clinmedi-182	58	7	that	that	SCONJ
clinmedi-182	58	8	all	all	PRON
clinmedi-182	58	9	of	of	ADP
clinmedi-182	58	10	the	the	DET
clinmedi-182	58	11	aforementioned	aforementioned	ADJ
clinmedi-182	58	12	adverse	adverse	ADJ
clinmedi-182	58	13	events	event	NOUN
clinmedi-182	58	14	were	be	AUX
clinmedi-182	58	15	unrelated	unrelated	ADJ
clinmedi-182	58	16	to	to	ADP
clinmedi-182	58	17	curcurouge	curcurouge	NOUN
clinmedi-182	58	18	○	○	NOUN
clinmedi-182	58	19	r	r	NOUN
clinmedi-182	58	20	.	.	PUNCT
clinmedi-182	59	1	one	one	NUM
clinmedi-182	59	2	case	case	NOUN
clinmedi-182	59	3	in	in	ADP
clinmedi-182	59	4	the	the	DET
clinmedi-182	59	5	high	high	ADJ
clinmedi-182	59	6	-	-	PUNCT
clinmedi-182	59	7	dose	dose	NOUN
clinmedi-182	59	8	group	group	NOUN
clinmedi-182	59	9	was	be	AUX
clinmedi-182	59	10	excluded	exclude	VERB
clinmedi-182	59	11	due	due	ADP
clinmedi-182	59	12	to	to	ADP
clinmedi-182	59	13	poor	poor	ADJ
clinmedi-182	59	14	drug	drug	NOUN
clinmedi-182	59	15	intake	intake	NOUN
clinmedi-182	59	16	compliance	compliance	NOUN
clinmedi-182	59	17	.	.	PUNCT
clinmedi-182	60	1	finally	finally	ADV
clinmedi-182	60	2	,	,	PUNCT
clinmedi-182	60	3	83	83	NUM
clinmedi-182	60	4	patients	patient	NOUN
clinmedi-182	60	5	(	(	PUNCT
clinmedi-182	60	6	27	27	NUM
clinmedi-182	60	7	in	in	ADP
clinmedi-182	60	8	the	the	DET
clinmedi-182	60	9	high	high	ADJ
clinmedi-182	60	10	-	-	PUNCT
clinmedi-182	60	11	dose	dose	NOUN
clinmedi-182	60	12	curcurouge	curcurouge	NOUN
clinmedi-182	60	13	○	○	PROPN
clinmedi-182	60	14	r	r	NOUN
clinmedi-182	60	15	group	group	NOUN
clinmedi-182	60	16	,	,	PUNCT
clinmedi-182	60	17	26	26	NUM
clinmedi-182	60	18	in	in	ADP
clinmedi-182	60	19	the	the	DET
clinmedi-182	60	20	low	low	ADJ
clinmedi-182	60	21	-	-	PUNCT
clinmedi-182	60	22	dose	dose	NOUN
clinmedi-182	60	23	curcurouge	curcurouge	NOUN
clinmedi-182	60	24	○	○	PROPN
clinmedi-182	60	25	r	r	NOUN
clinmedi-182	60	26	group	group	NOUN
clinmedi-182	60	27	,	,	PUNCT
clinmedi-182	60	28	and	and	CCONJ
clinmedi-182	60	29	30	30	NUM
clinmedi-182	60	30	in	in	ADP
clinmedi-182	60	31	the	the	DET
clinmedi-182	60	32	placebo	placebo	NOUN
clinmedi-182	60	33	group	group	NOUN
clinmedi-182	60	34	)	)	PUNCT
clinmedi-182	60	35	were	be	AUX
clinmedi-182	60	36	included	include	VERB
clinmedi-182	60	37	for	for	ADP
clinmedi-182	60	38	further	further	ADJ
clinmedi-182	60	39	analysis	analysis	NOUN
clinmedi-182	60	40	.	.	PUNCT
clinmedi-182	61	1	blood	blood	NOUN
clinmedi-182	61	2	biochemical	biochemical	ADJ
clinmedi-182	61	3	analyses	analysis	NOUN
clinmedi-182	61	4	were	be	AUX
clinmedi-182	61	5	performed	perform	VERB
clinmedi-182	61	6	before	before	ADP
clinmedi-182	61	7	the	the	DET
clinmedi-182	61	8	study	study	NOUN
clinmedi-182	61	9	and	and	CCONJ
clinmedi-182	61	10	after	after	ADP
clinmedi-182	61	11	12	12	NUM
clinmedi-182	61	12	weeks	week	NOUN
clinmedi-182	61	13	of	of	ADP
clinmedi-182	61	14	each	each	DET
clinmedi-182	61	15	intervention	intervention	NOUN
clinmedi-182	61	16	,	,	PUNCT
clinmedi-182	61	17	and	and	CCONJ
clinmedi-182	61	18	blood	blood	NOUN
clinmedi-182	61	19	curcumin	curcumin	NOUN
clinmedi-182	61	20	concentrations	concentration	NOUN
clinmedi-182	61	21	were	be	AUX
clinmedi-182	61	22	analyzed	analyze	VERB
clinmedi-182	61	23	after	after	ADP
clinmedi-182	61	24	12	12	NUM
clinmedi-182	61	25	weeks	week	NOUN
clinmedi-182	61	26	using	use	VERB
clinmedi-182	61	27	a	a	DET
clinmedi-182	61	28	previously	previously	ADV
clinmedi-182	61	29	described	describe	VERB
clinmedi-182	61	30	analytical	analytical	ADJ
clinmedi-182	61	31	method	method	NOUN
clinmedi-182	61	32	[	[	X
clinmedi-182	61	33	15	15	NUM
clinmedi-182	61	34	]	]	PUNCT
clinmedi-182	61	35	.	.	PUNCT
clinmedi-182	62	1	the	the	DET
clinmedi-182	62	2	patients	patient	NOUN
clinmedi-182	62	3	’	'	PUNCT
clinmedi-182	62	4	knee	knee	NOUN
clinmedi-182	62	5	symptoms	symptom	NOUN
clinmedi-182	62	6	were	be	AUX
clinmedi-182	62	7	assessed	assess	VERB
clinmedi-182	62	8	at	at	ADP
clinmedi-182	62	9	0	0	NUM
clinmedi-182	62	10	,	,	PUNCT
clinmedi-182	62	11	2	2	NUM
clinmedi-182	62	12	,	,	PUNCT
clinmedi-182	62	13	4	4	NUM
clinmedi-182	62	14	,	,	PUNCT
clinmedi-182	62	15	6	6	NUM
clinmedi-182	62	16	,	,	PUNCT
clinmedi-182	62	17	8	8	NUM
clinmedi-182	62	18	,	,	PUNCT
clinmedi-182	62	19	10	10	NUM
clinmedi-182	62	20	and	and	CCONJ
clinmedi-182	62	21	12	12	NUM
clinmedi-182	62	22	weeks	week	NOUN
clinmedi-182	62	23	according	accord	VERB
clinmedi-182	62	24	to	to	ADP
clinmedi-182	62	25	the	the	DET
clinmedi-182	62	26	japanese	japanese	ADJ
clinmedi-182	62	27	knee	knee	NOUN
clinmedi-182	62	28	cmi	cmi	PROPN
clinmedi-182	62	29	04	04	NUM
clinmedi-182	62	30	(	(	PUNCT
clinmedi-182	62	31	03	03	NUM
clinmedi-182	62	32	)	)	PUNCT
clinmedi-182	62	33	,	,	PUNCT
clinmedi-182	62	34	415−429	415−429	PROPN
clinmedi-182	62	35	cmi	cmi	PROPN
clinmedi-182	62	36	journal	journal	PROPN
clinmedi-182	62	37	418	418	NUM
clinmedi-182	62	38	cmi	cmi	PROPN
clinmedi-182	62	39	journal	journal	PROPN
clinmedi-182	62	40	yasuaki	yasuaki	PROPN
clinmedi-182	62	41	nakagawa	nakagawa	PROPN
clinmedi-182	62	42	,	,	PUNCT
clinmedi-182	62	43	md	md	PROPN
clinmedi-182	62	44	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	62	45	measure	measure	NOUN
clinmedi-182	62	46	(	(	PUNCT
clinmedi-182	62	47	jkom	jkom	NOUN
clinmedi-182	62	48	)	)	PUNCT
clinmedi-182	62	49	criteria	criterion	NOUN
clinmedi-182	63	1	[	[	X
clinmedi-182	63	2	16	16	NUM
clinmedi-182	63	3	]	]	PUNCT
clinmedi-182	63	4	,	,	PUNCT
clinmedi-182	63	5	the	the	DET
clinmedi-182	63	6	jkom	jkom	NOUN
clinmedi-182	63	7	knee	knee	NOUN
clinmedi-182	63	8	pain	pain	PROPN
clinmedi-182	63	9	vas	vas	PROPN
clinmedi-182	63	10	,	,	PUNCT
clinmedi-182	63	11	and	and	CCONJ
clinmedi-182	63	12	the	the	DET
clinmedi-182	63	13	knee	knee	NOUN
clinmedi-182	63	14	scoring	scoring	NOUN
clinmedi-182	63	15	system	system	NOUN
clinmedi-182	63	16	of	of	ADP
clinmedi-182	63	17	the	the	DET
clinmedi-182	63	18	japanese	japanese	ADJ
clinmedi-182	63	19	orthopedic	orthopedic	ADJ
clinmedi-182	63	20	association	association	PROPN
clinmedi-182	63	21	(	(	PUNCT
clinmedi-182	63	22	joa	joa	NOUN
clinmedi-182	63	23	)	)	PUNCT
clinmedi-182	63	24	knee	knee	NOUN
clinmedi-182	63	25	scoring	scoring	NOUN
clinmedi-182	63	26	system	system	NOUN
clinmedi-182	63	27	[	[	X
clinmedi-182	63	28	17	17	NUM
clinmedi-182	63	29	]	]	PUNCT
clinmedi-182	63	30	.	.	PUNCT
clinmedi-182	64	1	the	the	DET
clinmedi-182	64	2	jkom	jkom	NOUN
clinmedi-182	64	3	consists	consist	VERB
clinmedi-182	64	4	of	of	ADP
clinmedi-182	64	5	25	25	NUM
clinmedi-182	64	6	questions	question	NOUN
clinmedi-182	64	7	divided	divide	VERB
clinmedi-182	64	8	into	into	ADP
clinmedi-182	64	9	four	four	NUM
clinmedi-182	64	10	subcategories	subcategorie	NOUN
clinmedi-182	64	11	for	for	ADP
clinmedi-182	64	12	patient	patient	ADJ
clinmedi-182	64	13	self	self	NOUN
clinmedi-182	64	14	-	-	PUNCT
clinmedi-182	64	15	assessment	assessment	NOUN
clinmedi-182	64	16	(	(	PUNCT
clinmedi-182	64	17	pain	pain	NOUN
clinmedi-182	64	18	and	and	CCONJ
clinmedi-182	64	19	stiffness	stiffness	NOUN
clinmedi-182	64	20	,	,	PUNCT
clinmedi-182	64	21	condition	condition	NOUN
clinmedi-182	64	22	in	in	ADP
clinmedi-182	64	23	daily	daily	ADJ
clinmedi-182	64	24	life	life	NOUN
clinmedi-182	64	25	,	,	PUNCT
clinmedi-182	64	26	general	general	ADJ
clinmedi-182	64	27	activities	activity	NOUN
clinmedi-182	64	28	,	,	PUNCT
clinmedi-182	64	29	and	and	CCONJ
clinmedi-182	64	30	health	health	NOUN
clinmedi-182	64	31	conditions	condition	NOUN
clinmedi-182	64	32	)	)	PUNCT
clinmedi-182	64	33	and	and	CCONJ
clinmedi-182	64	34	is	be	AUX
clinmedi-182	64	35	based	base	VERB
clinmedi-182	64	36	on	on	ADP
clinmedi-182	64	37	the	the	DET
clinmedi-182	64	38	world	world	PROPN
clinmedi-182	64	39	health	health	PROPN
clinmedi-182	64	40	organization	organization	NOUN
clinmedi-182	64	41	’s	’s	PART
clinmedi-182	64	42	international	international	ADJ
clinmedi-182	64	43	classification	classification	NOUN
clinmedi-182	64	44	of	of	ADP
clinmedi-182	64	45	functioning	function	VERB
clinmedi-182	64	46	,	,	PUNCT
clinmedi-182	64	47	disability	disability	NOUN
clinmedi-182	64	48	,	,	PUNCT
clinmedi-182	64	49	and	and	CCONJ
clinmedi-182	64	50	health	health	NOUN
clinmedi-182	64	51	,	,	PUNCT
clinmedi-182	64	52	validated	validate	VERB
clinmedi-182	64	53	in	in	ADP
clinmedi-182	64	54	the	the	DET
clinmedi-182	64	55	same	same	ADJ
clinmedi-182	64	56	way	way	NOUN
clinmedi-182	64	57	as	as	ADP
clinmedi-182	64	58	the	the	DET
clinmedi-182	64	59	western	western	ADJ
clinmedi-182	64	60	ontario	ontario	PROPN
clinmedi-182	64	61	and	and	CCONJ
clinmedi-182	64	62	mcmaster	mcmaster	PROPN
clinmedi-182	64	63	universities	universities	PROPN
clinmedi-182	64	64	’	'	PUNCT
clinmedi-182	64	65	arthritis	arthritis	NOUN
clinmedi-182	64	66	index	index	NOUN
clinmedi-182	64	67	.	.	PUNCT
clinmedi-182	65	1	the	the	DET
clinmedi-182	65	2	joa	joa	NOUN
clinmedi-182	65	3	scale	scale	NOUN
clinmedi-182	65	4	assesses	assess	VERB
clinmedi-182	65	5	four	four	NUM
clinmedi-182	65	6	functions	function	NOUN
clinmedi-182	65	7	:	:	PUNCT
clinmedi-182	65	8	the	the	DET
clinmedi-182	65	9	ability	ability	NOUN
clinmedi-182	65	10	to	to	PART
clinmedi-182	65	11	walk	walk	VERB
clinmedi-182	65	12	(	(	PUNCT
clinmedi-182	65	13	30	30	NUM
clinmedi-182	65	14	points	point	NOUN
clinmedi-182	65	15	)	)	PUNCT
clinmedi-182	65	16	,	,	PUNCT
clinmedi-182	65	17	the	the	DET
clinmedi-182	65	18	ability	ability	NOUN
clinmedi-182	65	19	to	to	PART
clinmedi-182	65	20	climb	climb	VERB
clinmedi-182	65	21	up	up	ADP
clinmedi-182	65	22	and	and	CCONJ
clinmedi-182	65	23	down	down	ADP
clinmedi-182	65	24	stairs	stair	NOUN
clinmedi-182	65	25	(	(	PUNCT
clinmedi-182	65	26	25	25	NUM
clinmedi-182	65	27	points	point	NOUN
clinmedi-182	65	28	)	)	PUNCT
clinmedi-182	65	29	,	,	PUNCT
clinmedi-182	65	30	the	the	DET
clinmedi-182	65	31	range	range	NOUN
clinmedi-182	65	32	of	of	ADP
clinmedi-182	65	33	motion	motion	NOUN
clinmedi-182	65	34	(	(	PUNCT
clinmedi-182	65	35	rom	rom	NOUN
clinmedi-182	65	36	;	;	PUNCT
clinmedi-182	65	37	35	35	NUM
clinmedi-182	65	38	points	point	NOUN
clinmedi-182	65	39	)	)	PUNCT
clinmedi-182	65	40	,	,	PUNCT
clinmedi-182	65	41	and	and	CCONJ
clinmedi-182	65	42	joint	joint	ADJ
clinmedi-182	65	43	swelling	swelling	NOUN
clinmedi-182	65	44	(	(	PUNCT
clinmedi-182	65	45	10	10	NUM
clinmedi-182	65	46	points	point	NOUN
clinmedi-182	65	47	)	)	PUNCT
clinmedi-182	65	48	.	.	PUNCT
clinmedi-182	66	1	each	each	DET
clinmedi-182	66	2	knee	knee	NOUN
clinmedi-182	66	3	joint	joint	NOUN
clinmedi-182	66	4	can	can	AUX
clinmedi-182	66	5	achieve	achieve	VERB
clinmedi-182	66	6	a	a	DET
clinmedi-182	66	7	maximum	maximum	ADJ
clinmedi-182	66	8	score	score	NOUN
clinmedi-182	66	9	of	of	ADP
clinmedi-182	66	10	100	100	NUM
clinmedi-182	66	11	points	point	NOUN
clinmedi-182	66	12	on	on	ADP
clinmedi-182	66	13	the	the	DET
clinmedi-182	66	14	joa	joa	NOUN
clinmedi-182	66	15	scale	scale	NOUN
clinmedi-182	66	16	.	.	PUNCT
clinmedi-182	67	1	the	the	DET
clinmedi-182	67	2	improved	improved	ADJ
clinmedi-182	67	3	jkom	jkom	NOUN
clinmedi-182	67	4	,	,	PUNCT
clinmedi-182	67	5	vas	vas	X
clinmedi-182	67	6	,	,	PUNCT
clinmedi-182	67	7	and	and	CCONJ
clinmedi-182	67	8	joa	joa	NOUN
clinmedi-182	67	9	scores	score	NOUN
clinmedi-182	67	10	(	(	PUNCT
clinmedi-182	67	11	the	the	DET
clinmedi-182	67	12	differences	difference	NOUN
clinmedi-182	67	13	between	between	ADP
clinmedi-182	67	14	the	the	DET
clinmedi-182	67	15	scores	score	NOUN
clinmedi-182	67	16	at	at	ADP
clinmedi-182	67	17	each	each	DET
clinmedi-182	67	18	time	time	NOUN
clinmedi-182	67	19	point	point	NOUN
clinmedi-182	67	20	and	and	CCONJ
clinmedi-182	67	21	before	before	ADP
clinmedi-182	67	22	the	the	DET
clinmedi-182	67	23	study	study	NOUN
clinmedi-182	67	24	)	)	PUNCT
clinmedi-182	67	25	were	be	AUX
clinmedi-182	67	26	calculated	calculate	VERB
clinmedi-182	67	27	.	.	PUNCT
clinmedi-182	68	1	furthermore	furthermore	ADV
clinmedi-182	68	2	,	,	PUNCT
clinmedi-182	68	3	adverse	adverse	ADJ
clinmedi-182	68	4	events	event	NOUN
clinmedi-182	68	5	and	and	CCONJ
clinmedi-182	68	6	the	the	DET
clinmedi-182	68	7	number	number	NOUN
clinmedi-182	68	8	of	of	ADP
clinmedi-182	68	9	celecoxib	celecoxib	NOUN
clinmedi-182	68	10	pills	pill	NOUN
clinmedi-182	68	11	taken	take	VERB
clinmedi-182	68	12	during	during	ADP
clinmedi-182	68	13	the	the	DET
clinmedi-182	68	14	12	12	NUM
clinmedi-182	68	15	-	-	PUNCT
clinmedi-182	68	16	week	week	NOUN
clinmedi-182	68	17	period	period	NOUN
clinmedi-182	68	18	were	be	AUX
clinmedi-182	68	19	recorded	record	VERB
clinmedi-182	68	20	.	.	PUNCT
clinmedi-182	69	1	we	we	PRON
clinmedi-182	69	2	also	also	ADV
clinmedi-182	69	3	calculated	calculate	VERB
clinmedi-182	69	4	nsaids	nsaid	NOUN
clinmedi-182	69	5	necessity	necessity	NOUN
clinmedi-182	69	6	in	in	ADP
clinmedi-182	69	7	3	3	NUM
clinmedi-182	69	8	groups	group	NOUN
clinmedi-182	69	9	.	.	PUNCT
clinmedi-182	70	1	a	a	DET
clinmedi-182	70	2	timed	time	VERB
clinmedi-182	70	3	up	up	ADP
clinmedi-182	70	4	-	-	PUNCT
clinmedi-182	70	5	and	and	CCONJ
clinmedi-182	70	6	-	-	PUNCT
clinmedi-182	70	7	go	go	VERB
clinmedi-182	70	8	test	test	NOUN
clinmedi-182	70	9	(	(	PUNCT
clinmedi-182	70	10	tug	tug	NOUN
clinmedi-182	70	11	)	)	PUNCT
clinmedi-182	70	12	and	and	CCONJ
clinmedi-182	70	13	the	the	DET
clinmedi-182	70	14	rom	rom	NOUN
clinmedi-182	70	15	of	of	ADP
clinmedi-182	70	16	their	their	PRON
clinmedi-182	70	17	knee	knee	NOUN
clinmedi-182	70	18	joints	joint	NOUN
clinmedi-182	70	19	were	be	AUX
clinmedi-182	70	20	measured	measure	VERB
clinmedi-182	70	21	before	before	ADP
clinmedi-182	70	22	the	the	DET
clinmedi-182	70	23	study	study	NOUN
clinmedi-182	70	24	and	and	CCONJ
clinmedi-182	70	25	after	after	ADP
clinmedi-182	70	26	12	12	NUM
clinmedi-182	70	27	weeks	week	NOUN
clinmedi-182	70	28	of	of	ADP
clinmedi-182	70	29	each	each	DET
clinmedi-182	70	30	intervention	intervention	NOUN
clinmedi-182	70	31	.	.	PUNCT
clinmedi-182	71	1	these	these	DET
clinmedi-182	71	2	performance	performance	NOUN
clinmedi-182	71	3	-	-	PUNCT
clinmedi-182	71	4	based	base	VERB
clinmedi-182	71	5	measures	measure	NOUN
clinmedi-182	71	6	are	be	AUX
clinmedi-182	71	7	recommended	recommend	VERB
clinmedi-182	71	8	as	as	ADP
clinmedi-182	71	9	validated	validate	VERB
clinmedi-182	71	10	outcome	outcome	NOUN
clinmedi-182	71	11	measures	measure	NOUN
clinmedi-182	71	12	by	by	ADP
clinmedi-182	71	13	the	the	DET
clinmedi-182	71	14	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	71	15	research	research	NOUN
clinmedi-182	71	16	society	society	NOUN
clinmedi-182	71	17	international	international	ADJ
clinmedi-182	71	18	to	to	PART
clinmedi-182	71	19	assess	assess	VERB
clinmedi-182	71	20	physical	physical	ADJ
clinmedi-182	71	21	function	function	NOUN
clinmedi-182	71	22	in	in	ADP
clinmedi-182	71	23	adults	adult	NOUN
clinmedi-182	71	24	with	with	ADP
clinmedi-182	71	25	knee	knee	NOUN
clinmedi-182	71	26	oa	oa	X
clinmedi-182	72	1	[	[	X
clinmedi-182	72	2	18,19	18,19	NUM
clinmedi-182	72	3	]	]	PUNCT
clinmedi-182	72	4	.	.	PUNCT
clinmedi-182	73	1	in	in	ADP
clinmedi-182	73	2	tug	tug	PROPN
clinmedi-182	73	3	,	,	PUNCT
clinmedi-182	73	4	participants	participant	NOUN
clinmedi-182	73	5	were	be	AUX
clinmedi-182	73	6	asked	ask	VERB
clinmedi-182	73	7	to	to	PART
clinmedi-182	73	8	stand	stand	VERB
clinmedi-182	73	9	up	up	ADP
clinmedi-182	73	10	,	,	PUNCT
clinmedi-182	73	11	walk	walk	VERB
clinmedi-182	73	12	around	around	ADP
clinmedi-182	73	13	a	a	DET
clinmedi-182	73	14	cone	cone	NOUN
clinmedi-182	73	15	three	three	NUM
clinmedi-182	73	16	meters	meter	NOUN
clinmedi-182	73	17	away	away	ADV
clinmedi-182	73	18	,	,	PUNCT
clinmedi-182	73	19	and	and	CCONJ
clinmedi-182	73	20	then	then	ADV
clinmedi-182	73	21	return	return	VERB
clinmedi-182	73	22	to	to	ADP
clinmedi-182	73	23	their	their	PRON
clinmedi-182	73	24	chairs	chair	NOUN
clinmedi-182	73	25	at	at	ADP
clinmedi-182	73	26	their	their	PRON
clinmedi-182	73	27	regular	regular	ADJ
clinmedi-182	73	28	pace	pace	NOUN
clinmedi-182	73	29	.	.	PUNCT
clinmedi-182	74	1	the	the	DET
clinmedi-182	74	2	chair	chair	NOUN
clinmedi-182	74	3	had	have	VERB
clinmedi-182	74	4	no	no	DET
clinmedi-182	74	5	arms	arm	NOUN
clinmedi-182	74	6	,	,	PUNCT
clinmedi-182	74	7	and	and	CCONJ
clinmedi-182	74	8	a	a	DET
clinmedi-182	74	9	height	height	NOUN
clinmedi-182	74	10	of	of	ADP
clinmedi-182	74	11	50	50	NUM
clinmedi-182	74	12	cm	cm	NOUN
clinmedi-182	74	13	from	from	ADP
clinmedi-182	74	14	the	the	DET
clinmedi-182	74	15	seated	seated	ADJ
clinmedi-182	74	16	position	position	NOUN
clinmedi-182	74	17	.	.	PUNCT
clinmedi-182	75	1	the	the	DET
clinmedi-182	75	2	time	time	NOUN
clinmedi-182	75	3	and	and	CCONJ
clinmedi-182	75	4	number	number	NOUN
clinmedi-182	75	5	of	of	ADP
clinmedi-182	75	6	gaits	gait	NOUN
clinmedi-182	75	7	required	require	VERB
clinmedi-182	75	8	to	to	PART
clinmedi-182	75	9	complete	complete	VERB
clinmedi-182	75	10	this	this	DET
clinmedi-182	75	11	task	task	NOUN
clinmedi-182	75	12	were	be	AUX
clinmedi-182	75	13	recorded	record	VERB
clinmedi-182	75	14	.	.	PUNCT
clinmedi-182	76	1	the	the	DET
clinmedi-182	76	2	primary	primary	ADJ
clinmedi-182	76	3	endpoints	endpoint	NOUN
clinmedi-182	76	4	were	be	AUX
clinmedi-182	76	5	jkom	jkom	NOUN
clinmedi-182	76	6	,	,	PUNCT
clinmedi-182	76	7	vas	vas	X
clinmedi-182	76	8	,	,	PUNCT
clinmedi-182	76	9	and	and	CCONJ
clinmedi-182	76	10	joa	joa	PROPN
clinmedi-182	76	11	knee	knee	NOUN
clinmedi-182	76	12	score	score	NOUN
clinmedi-182	76	13	,	,	PUNCT
clinmedi-182	76	14	as	as	ADV
clinmedi-182	76	15	well	well	ADV
clinmedi-182	76	16	as	as	ADP
clinmedi-182	76	17	nsaid	nsaid	ADJ
clinmedi-182	76	18	necessities	necessity	NOUN
clinmedi-182	76	19	.	.	PUNCT
clinmedi-182	77	1	the	the	DET
clinmedi-182	77	2	secondary	secondary	ADJ
clinmedi-182	77	3	endpoints	endpoint	NOUN
clinmedi-182	77	4	were	be	AUX
clinmedi-182	77	5	tug	tug	NOUN
clinmedi-182	77	6	,	,	PUNCT
clinmedi-182	77	7	knee	knee	NOUN
clinmedi-182	77	8	rom	rom	PROPN
clinmedi-182	77	9	,	,	PUNCT
clinmedi-182	77	10	blood	blood	NOUN
clinmedi-182	77	11	biochemistry	biochemistry	NOUN
clinmedi-182	77	12	analyses	analysis	NOUN
clinmedi-182	77	13	,	,	PUNCT
clinmedi-182	77	14	and	and	CCONJ
clinmedi-182	77	15	adverse	adverse	ADJ
clinmedi-182	77	16	events	event	NOUN
clinmedi-182	77	17	.	.	PUNCT
clinmedi-182	78	1	the	the	DET
clinmedi-182	78	2	primary	primary	ADJ
clinmedi-182	78	3	analysis	analysis	NOUN
clinmedi-182	78	4	was	be	AUX
clinmedi-182	78	5	performed	perform	VERB
clinmedi-182	78	6	following	follow	VERB
clinmedi-182	78	7	the	the	DET
clinmedi-182	78	8	full	full	ADJ
clinmedi-182	78	9	-	-	PUNCT
clinmedi-182	78	10	analysis	analysis	NOUN
clinmedi-182	78	11	-	-	PUNCT
clinmedi-182	78	12	set	set	VERB
clinmedi-182	78	13	principal	principal	NOUN
clinmedi-182	78	14	.	.	PUNCT
clinmedi-182	79	1	data	datum	NOUN
clinmedi-182	79	2	were	be	AUX
clinmedi-182	79	3	expressed	express	VERB
clinmedi-182	79	4	as	as	ADP
clinmedi-182	79	5	mean	mean	ADJ
clinmedi-182	79	6	and	and	CCONJ
clinmedi-182	79	7	standard	standard	ADJ
clinmedi-182	79	8	deviation	deviation	NOUN
clinmedi-182	79	9	(	(	PUNCT
clinmedi-182	79	10	sd	sd	NOUN
clinmedi-182	79	11	)	)	PUNCT
clinmedi-182	79	12	and	and	CCONJ
clinmedi-182	79	13	compared	compare	VERB
clinmedi-182	79	14	among	among	ADP
clinmedi-182	79	15	groups	group	NOUN
clinmedi-182	79	16	using	use	VERB
clinmedi-182	79	17	a	a	DET
clinmedi-182	79	18	three	three	NUM
clinmedi-182	79	19	-	-	PUNCT
clinmedi-182	79	20	factor	factor	NOUN
clinmedi-182	79	21	analysis	analysis	NOUN
clinmedi-182	79	22	of	of	ADP
clinmedi-182	79	23	variance	variance	NOUN
clinmedi-182	79	24	for	for	ADP
clinmedi-182	79	25	parametric	parametric	ADJ
clinmedi-182	79	26	variables	variable	NOUN
clinmedi-182	79	27	or	or	CCONJ
clinmedi-182	79	28	the	the	DET
clinmedi-182	79	29	kruskalwallis	kruskalwallis	PROPN
clinmedi-182	79	30	test	test	NOUN
clinmedi-182	79	31	for	for	ADP
clinmedi-182	79	32	non	non	ADJ
clinmedi-182	79	33	-	-	ADJ
clinmedi-182	79	34	parametric	parametric	ADJ
clinmedi-182	79	35	variables	variable	NOUN
clinmedi-182	79	36	.	.	PUNCT
clinmedi-182	80	1	a	a	DET
clinmedi-182	80	2	paired	pair	VERB
clinmedi-182	80	3	student	student	NOUN
clinmedi-182	80	4	’s	’s	PART
clinmedi-182	80	5	t	t	PROPN
clinmedi-182	80	6	-	-	PUNCT
clinmedi-182	80	7	test	test	NOUN
clinmedi-182	80	8	was	be	AUX
clinmedi-182	80	9	used	use	VERB
clinmedi-182	80	10	to	to	PART
clinmedi-182	80	11	compare	compare	VERB
clinmedi-182	80	12	data	datum	NOUN
clinmedi-182	80	13	at	at	ADP
clinmedi-182	80	14	0	0	NUM
clinmedi-182	80	15	and	and	CCONJ
clinmedi-182	80	16	12	12	NUM
clinmedi-182	80	17	weeks	week	NOUN
clinmedi-182	80	18	of	of	ADP
clinmedi-182	80	19	treatment	treatment	NOUN
clinmedi-182	80	20	in	in	ADP
clinmedi-182	80	21	each	each	DET
clinmedi-182	80	22	group	group	NOUN
clinmedi-182	80	23	.	.	PUNCT
clinmedi-182	81	1	categorical	categorical	ADJ
clinmedi-182	81	2	data	datum	NOUN
clinmedi-182	81	3	were	be	AUX
clinmedi-182	81	4	compared	compare	VERB
clinmedi-182	81	5	using	use	VERB
clinmedi-182	81	6	the	the	DET
clinmedi-182	81	7	chi	chi	ADJ
clinmedi-182	81	8	-	-	PUNCT
clinmedi-182	81	9	squared	square	VERB
clinmedi-182	81	10	test	test	NOUN
clinmedi-182	81	11	.	.	PUNCT
clinmedi-182	82	1	the	the	DET
clinmedi-182	82	2	level	level	NOUN
clinmedi-182	82	3	of	of	ADP
clinmedi-182	82	4	statistical	statistical	ADJ
clinmedi-182	82	5	significance	significance	NOUN
clinmedi-182	82	6	was	be	AUX
clinmedi-182	82	7	set	set	VERB
clinmedi-182	82	8	to	to	ADP
clinmedi-182	82	9	a	a	DET
clinmedi-182	82	10	p	p	NOUN
clinmedi-182	82	11	value	value	NOUN
clinmedi-182	82	12	of	of	ADP
clinmedi-182	82	13	less	less	ADJ
clinmedi-182	82	14	than	than	ADP
clinmedi-182	82	15	0.05	0.05	NUM
clinmedi-182	82	16	.	.	PUNCT
clinmedi-182	83	1	all	all	DET
clinmedi-182	83	2	statistical	statistical	ADJ
clinmedi-182	83	3	analyses	analysis	NOUN
clinmedi-182	83	4	were	be	AUX
clinmedi-182	83	5	performed	perform	VERB
clinmedi-182	83	6	using	use	VERB
clinmedi-182	83	7	ezr	ezr	NOUN
clinmedi-182	83	8	,	,	PUNCT
clinmedi-182	83	9	a	a	DET
clinmedi-182	83	10	modified	modify	VERB
clinmedi-182	83	11	version	version	NOUN
clinmedi-182	83	12	of	of	ADP
clinmedi-182	83	13	the	the	DET
clinmedi-182	83	14	r	r	NOUN
clinmedi-182	83	15	commander	commander	NOUN
clinmedi-182	83	16	designed	design	VERB
clinmedi-182	83	17	to	to	PART
clinmedi-182	83	18	include	include	VERB
clinmedi-182	83	19	statistical	statistical	ADJ
clinmedi-182	83	20	functions	function	NOUN
clinmedi-182	83	21	frequently	frequently	ADV
clinmedi-182	83	22	used	use	VERB
clinmedi-182	83	23	in	in	ADP
clinmedi-182	83	24	biostatistics	biostatistic	NOUN
clinmedi-182	83	25	.	.	PUNCT
clinmedi-182	84	1	results	result	VERB
clinmedi-182	84	2	the	the	DET
clinmedi-182	84	3	baseline	baseline	PROPN
clinmedi-182	84	4	characteristics	characteristic	NOUN
clinmedi-182	84	5	of	of	ADP
clinmedi-182	84	6	the	the	DET
clinmedi-182	84	7	study	study	NOUN
clinmedi-182	84	8	patients	patient	NOUN
clinmedi-182	84	9	in	in	ADP
clinmedi-182	84	10	each	each	PRON
clinmedi-182	84	11	of	of	ADP
clinmedi-182	84	12	the	the	DET
clinmedi-182	84	13	three	three	NUM
clinmedi-182	84	14	groups	group	NOUN
clinmedi-182	84	15	are	be	AUX
clinmedi-182	84	16	summarized	summarize	VERB
clinmedi-182	84	17	in	in	ADP
clinmedi-182	84	18	table	table	NOUN
clinmedi-182	84	19	1	1	NUM
clinmedi-182	84	20	.	.	PUNCT
clinmedi-182	85	1	the	the	DET
clinmedi-182	85	2	majority	majority	NOUN
clinmedi-182	85	3	of	of	ADP
clinmedi-182	85	4	patients	patient	NOUN
clinmedi-182	85	5	were	be	AUX
clinmedi-182	85	6	female	female	ADJ
clinmedi-182	85	7	,	,	PUNCT
clinmedi-182	85	8	accounting	account	VERB
clinmedi-182	85	9	for	for	ADP
clinmedi-182	85	10	77.8	77.8	NUM
clinmedi-182	85	11	%	%	NOUN
clinmedi-182	85	12	in	in	ADP
clinmedi-182	85	13	the	the	DET
clinmedi-182	85	14	high	high	ADV
clinmedi-182	85	15	-	-	PUNCT
clinmedi-182	85	16	dose	dose	NOUN
clinmedi-182	85	17	of	of	ADP
clinmedi-182	85	18	curcurouge	curcurouge	NOUN
clinmedi-182	85	19	○	○	PROPN
clinmedi-182	85	20	r	r	NOUN
clinmedi-182	85	21	group	group	NOUN
clinmedi-182	85	22	,	,	PUNCT
clinmedi-182	85	23	88.5	88.5	NUM
clinmedi-182	85	24	%	%	NOUN
clinmedi-182	85	25	in	in	ADP
clinmedi-182	85	26	the	the	DET
clinmedi-182	85	27	low	low	ADV
clinmedi-182	85	28	-	-	PUNCT
clinmedi-182	85	29	dose	dose	NOUN
clinmedi-182	85	30	of	of	ADP
clinmedi-182	85	31	curcurouge	curcurouge	NOUN
clinmedi-182	85	32	○	○	PROPN
clinmedi-182	85	33	r	r	NOUN
clinmedi-182	85	34	group	group	NOUN
clinmedi-182	85	35	,	,	PUNCT
clinmedi-182	85	36	and	and	CCONJ
clinmedi-182	85	37	70.0	70.0	NUM
clinmedi-182	85	38	%	%	NOUN
clinmedi-182	85	39	in	in	ADP
clinmedi-182	85	40	the	the	DET
clinmedi-182	85	41	placebo	placebo	NOUN
clinmedi-182	85	42	group	group	NOUN
clinmedi-182	85	43	.	.	PUNCT
clinmedi-182	86	1	the	the	DET
clinmedi-182	86	2	patient	patient	ADJ
clinmedi-182	86	3	ages	age	NOUN
clinmedi-182	86	4	were	be	AUX
clinmedi-182	86	5	also	also	ADV
clinmedi-182	86	6	comparable	comparable	ADJ
clinmedi-182	86	7	across	across	ADP
clinmedi-182	86	8	the	the	DET
clinmedi-182	86	9	three	three	NUM
clinmedi-182	86	10	groups	group	NOUN
clinmedi-182	86	11	.	.	PUNCT
clinmedi-182	87	1	the	the	DET
clinmedi-182	87	2	kl	kl	NOUN
clinmedi-182	87	3	grading	grade	VERB
clinmedi-182	87	4	system	system	NOUN
clinmedi-182	87	5	was	be	AUX
clinmedi-182	87	6	used	use	VERB
clinmedi-182	87	7	to	to	PART
clinmedi-182	87	8	quantify	quantify	VERB
clinmedi-182	87	9	disease	disease	NOUN
clinmedi-182	87	10	severity	severity	NOUN
clinmedi-182	87	11	in	in	ADP
clinmedi-182	87	12	order	order	NOUN
clinmedi-182	87	13	to	to	PART
clinmedi-182	87	14	effectively	effectively	ADV
clinmedi-182	87	15	randomize	randomize	VERB
clinmedi-182	87	16	disease	disease	NOUN
clinmedi-182	87	17	status	status	NOUN
clinmedi-182	87	18	upon	upon	SCONJ
clinmedi-182	87	19	study	study	NOUN
clinmedi-182	87	20	entry	entry	NOUN
clinmedi-182	87	21	between	between	ADP
clinmedi-182	87	22	groups	group	NOUN
clinmedi-182	87	23	.	.	PUNCT
clinmedi-182	88	1	for	for	ADP
clinmedi-182	88	2	kl	kl	PROPN
clinmedi-182	88	3	grade	grade	PROPN
clinmedi-182	88	4	ii	ii	PROPN
clinmedi-182	88	5	,	,	PUNCT
clinmedi-182	88	6	there	there	PRON
clinmedi-182	88	7	were	be	VERB
clinmedi-182	88	8	nine	nine	NUM
clinmedi-182	88	9	cases	case	NOUN
clinmedi-182	88	10	in	in	ADP
clinmedi-182	88	11	the	the	DET
clinmedi-182	88	12	high	high	ADJ
clinmedi-182	88	13	-	-	PUNCT
clinmedi-182	88	14	dose	dose	NOUN
clinmedi-182	88	15	curcurouge	curcurouge	NOUN
clinmedi-182	88	16	○	○	PROPN
clinmedi-182	88	17	r	r	NOUN
clinmedi-182	88	18	group	group	NOUN
clinmedi-182	88	19	,	,	PUNCT
clinmedi-182	88	20	eight	eight	NUM
clinmedi-182	88	21	cases	case	NOUN
clinmedi-182	88	22	in	in	ADP
clinmedi-182	88	23	the	the	DET
clinmedi-182	88	24	low	low	ADJ
clinmedi-182	88	25	-	-	PUNCT
clinmedi-182	88	26	dose	dose	NOUN
clinmedi-182	88	27	curcurouge	curcurouge	NOUN
clinmedi-182	88	28	○	○	PROPN
clinmedi-182	88	29	r	r	NOUN
clinmedi-182	88	30	group	group	NOUN
clinmedi-182	88	31	,	,	PUNCT
clinmedi-182	88	32	and	and	CCONJ
clinmedi-182	88	33	10	10	NUM
clinmedi-182	88	34	cases	case	NOUN
clinmedi-182	88	35	in	in	ADP
clinmedi-182	88	36	the	the	DET
clinmedi-182	88	37	placebo	placebo	NOUN
clinmedi-182	88	38	group	group	NOUN
clinmedi-182	88	39	.	.	PUNCT
clinmedi-182	89	1	for	for	ADP
clinmedi-182	89	2	kl	kl	PROPN
clinmedi-182	89	3	grade	grade	PROPN
clinmedi-182	89	4	iii	iii	PROPN
clinmedi-182	89	5	,	,	PUNCT
clinmedi-182	89	6	there	there	PRON
clinmedi-182	89	7	were	be	VERB
clinmedi-182	89	8	18	18	NUM
clinmedi-182	89	9	cases	case	NOUN
clinmedi-182	89	10	in	in	ADP
clinmedi-182	89	11	the	the	DET
clinmedi-182	89	12	high	high	ADJ
clinmedi-182	89	13	-	-	PUNCT
clinmedi-182	89	14	dose	dose	NOUN
clinmedi-182	89	15	group	group	NOUN
clinmedi-182	89	16	,	,	PUNCT
clinmedi-182	89	17	18	18	NUM
clinmedi-182	89	18	cases	case	NOUN
clinmedi-182	89	19	in	in	ADP
clinmedi-182	89	20	the	the	DET
clinmedi-182	89	21	low	low	ADJ
clinmedi-182	89	22	-	-	PUNCT
clinmedi-182	89	23	dose	dose	NOUN
clinmedi-182	89	24	group	group	NOUN
clinmedi-182	89	25	,	,	PUNCT
clinmedi-182	89	26	and	and	CCONJ
clinmedi-182	89	27	20	20	NUM
clinmedi-182	89	28	cases	case	NOUN
clinmedi-182	89	29	in	in	ADP
clinmedi-182	89	30	the	the	DET
clinmedi-182	89	31	placebo	placebo	NOUN
clinmedi-182	89	32	group	group	NOUN
clinmedi-182	89	33	.	.	PUNCT
clinmedi-182	90	1	there	there	PRON
clinmedi-182	90	2	were	be	VERB
clinmedi-182	90	3	no	no	DET
clinmedi-182	90	4	statistical	statistical	ADJ
clinmedi-182	90	5	differences	difference	NOUN
clinmedi-182	90	6	in	in	ADP
clinmedi-182	90	7	the	the	DET
clinmedi-182	90	8	baseline	baseline	NOUN
clinmedi-182	90	9	characteristics	characteristic	NOUN
clinmedi-182	90	10	,	,	PUNCT
clinmedi-182	90	11	as	as	ADV
clinmedi-182	90	12	well	well	ADV
clinmedi-182	90	13	as	as	ADP
clinmedi-182	90	14	compliance	compliance	NOUN
clinmedi-182	90	15	,	,	PUNCT
clinmedi-182	90	16	among	among	ADP
clinmedi-182	90	17	the	the	DET
clinmedi-182	90	18	three	three	NUM
clinmedi-182	90	19	groups	group	NOUN
clinmedi-182	90	20	.	.	PUNCT
clinmedi-182	91	1	cmi	cmi	PROPN
clinmedi-182	91	2	04	04	PROPN
clinmedi-182	91	3	(	(	PUNCT
clinmedi-182	91	4	03	03	NUM
clinmedi-182	91	5	)	)	PUNCT
clinmedi-182	91	6	,	,	PUNCT
clinmedi-182	91	7	415−429	415−429	PROPN
clinmedi-182	91	8	cmi	cmi	PROPN
clinmedi-182	91	9	journal	journal	PROPN
clinmedi-182	91	10	419	419	NUM
clinmedi-182	91	11	cmi	cmi	PROPN
clinmedi-182	91	12	journal	journal	PROPN
clinmedi-182	91	13	yasuaki	yasuaki	PROPN
clinmedi-182	91	14	nakagawa	nakagawa	PROPN
clinmedi-182	91	15	,	,	PUNCT
clinmedi-182	91	16	md	md	PROPN
clinmedi-182	91	17	figure1	figure1	PROPN
clinmedi-182	91	18	.	.	PUNCT
clinmedi-182	92	1	patient	patient	PROPN
clinmedi-182	92	2	flowchart	flowchart	PROPN
clinmedi-182	92	3	for	for	ADP
clinmedi-182	92	4	the	the	DET
clinmedi-182	92	5	study	study	NOUN
clinmedi-182	92	6	table	table	NOUN
clinmedi-182	92	7	1	1	NUM
clinmedi-182	92	8	.	.	PUNCT
clinmedi-182	92	9	baseline	baseline	PROPN
clinmedi-182	92	10	characteristics	characteristic	NOUN
clinmedi-182	92	11	of	of	ADP
clinmedi-182	92	12	the	the	DET
clinmedi-182	92	13	studied	study	VERB
clinmedi-182	92	14	groups	group	NOUN
clinmedi-182	92	15	.	.	PUNCT
clinmedi-182	93	1	curcurouge	curcurouge	PROPN
clinmedi-182	93	2	®	®	NOUN
clinmedi-182	93	3	90	90	NUM
clinmedi-182	93	4	mg	mg	NOUN
clinmedi-182	93	5	curcurouge	curcurouge	NOUN
clinmedi-182	93	6	®	®	NOUN
clinmedi-182	93	7	30	30	NUM
clinmedi-182	93	8	mg	mg	PROPN
clinmedi-182	93	9	placebo	placebo	NOUN
clinmedi-182	93	10	p	p	NOUN
clinmedi-182	93	11	-	-	PUNCT
clinmedi-182	93	12	value	value	NOUN
clinmedi-182	93	13	number	number	NOUN
clinmedi-182	93	14	of	of	ADP
clinmedi-182	93	15	patients	patient	NOUN
clinmedi-182	93	16	27	27	NUM
clinmedi-182	93	17	26	26	NUM
clinmedi-182	93	18	30	30	NUM
clinmedi-182	93	19	male	male	NOUN
clinmedi-182	93	20	/	/	SYM
clinmedi-182	93	21	female	female	NOUN
clinmedi-182	94	1	6/21	6/21	NUM
clinmedi-182	94	2	3/23	3/23	NUM
clinmedi-182	94	3	9/21	9/21	NUM
clinmedi-182	94	4	0.251	0.251	NUM
clinmedi-182	94	5	age	age	NOUN
clinmedi-182	94	6	(	(	PUNCT
clinmedi-182	94	7	mean	mean	NOUN
clinmedi-182	94	8	±	±	NUM
clinmedi-182	94	9	sd	sd	NOUN
clinmedi-182	94	10	)	)	PUNCT
clinmedi-182	94	11	71.1	71.1	NUM
clinmedi-182	94	12	±	±	NUM
clinmedi-182	94	13	6.5	6.5	NUM
clinmedi-182	94	14	71.4	71.4	NUM
clinmedi-182	94	15	±	±	NUM
clinmedi-182	94	16	10.3	10.3	NUM
clinmedi-182	94	17	70.1	70.1	NUM
clinmedi-182	94	18	±	±	NUM
clinmedi-182	94	19	9.5	9.5	NUM
clinmedi-182	94	20	0.837	0.837	NUM
clinmedi-182	94	21	kellgren	kellgren	ADJ
clinmedi-182	94	22	-	-	PUNCT
clinmedi-182	94	23	lawrence	lawrence	NOUN
clinmedi-182	94	24	classification	classification	NOUN
clinmedi-182	94	25	(	(	PUNCT
clinmedi-182	94	26	ⅱ/ⅲ	ⅱ/ⅲ	NOUN
clinmedi-182	94	27	)	)	PUNCT
clinmedi-182	94	28	9/18	9/18	NUM
clinmedi-182	94	29	8/18	8/18	NUM
clinmedi-182	94	30	10/20	10/20	NUM
clinmedi-182	94	31	0.999	0.999	NUM
clinmedi-182	94	32	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	94	33	lesion	lesion	NOUN
clinmedi-182	94	34	(	(	PUNCT
clinmedi-182	94	35	one	one	NUM
clinmedi-182	94	36	knee	knee	NOUN
clinmedi-182	94	37	/	/	SYM
clinmedi-182	94	38	both	both	PRON
clinmedi-182	94	39	)	)	PUNCT
clinmedi-182	94	40	19/8	19/8	NUM
clinmedi-182	95	1	18/8	18/8	NUM
clinmedi-182	95	2	19/11	19/11	NUM
clinmedi-182	95	3	0.875	0.875	NUM
clinmedi-182	95	4	joa	joa	NOUN
clinmedi-182	95	5	score	score	NOUN
clinmedi-182	95	6	(	(	PUNCT
clinmedi-182	95	7	mean	mean	PROPN
clinmedi-182	95	8	±	±	NUM
clinmedi-182	95	9	sd	sd	NOUN
clinmedi-182	95	10	)	)	PUNCT
clinmedi-182	95	11	72.3	72.3	NUM
clinmedi-182	95	12	±	±	NUM
clinmedi-182	95	13	11.1	11.1	NUM
clinmedi-182	95	14	73.4	73.4	NUM
clinmedi-182	95	15	±	±	NUM
clinmedi-182	95	16	9.2	9.2	NUM
clinmedi-182	95	17	73.2	73.2	NUM
clinmedi-182	95	18	±	±	NUM
clinmedi-182	95	19	12.1	12.1	NUM
clinmedi-182	95	20	0.933	0.933	NUM
clinmedi-182	95	21	jkom	jkom	NOUN
clinmedi-182	95	22	score	score	NOUN
clinmedi-182	95	23	(	(	PUNCT
clinmedi-182	95	24	mean	mean	PROPN
clinmedi-182	95	25	±	±	NUM
clinmedi-182	95	26	sd	sd	NOUN
clinmedi-182	95	27	)	)	PUNCT
clinmedi-182	95	28	30.2	30.2	NUM
clinmedi-182	95	29	±	±	NUM
clinmedi-182	95	30	19.0	19.0	NUM
clinmedi-182	95	31	31.3	31.3	NUM
clinmedi-182	95	32	±	±	NUM
clinmedi-182	95	33	19.8	19.8	NUM
clinmedi-182	95	34	32.3	32.3	NUM
clinmedi-182	95	35	±	±	NUM
clinmedi-182	95	36	16.6	16.6	NUM
clinmedi-182	95	37	0.911	0.911	NUM
clinmedi-182	95	38	vas	vas	NOUN
clinmedi-182	95	39	score	score	NOUN
clinmedi-182	95	40	(	(	PUNCT
clinmedi-182	95	41	mean	mean	PROPN
clinmedi-182	95	42	±	±	NUM
clinmedi-182	95	43	sd	sd	NOUN
clinmedi-182	95	44	)	)	PUNCT
clinmedi-182	95	45	0.46	0.46	NUM
clinmedi-182	95	46	±	±	NUM
clinmedi-182	95	47	0.24	0.24	NUM
clinmedi-182	95	48	0.39	0.39	NUM
clinmedi-182	95	49	±	±	NUM
clinmedi-182	95	50	0.24	0.24	NUM
clinmedi-182	95	51	0.49	0.49	NUM
clinmedi-182	95	52	±	±	NUM
clinmedi-182	95	53	0.23	0.23	NUM
clinmedi-182	95	54	0.283	0.283	NUM
clinmedi-182	95	55	cmi	cmi	NOUN
clinmedi-182	95	56	04	04	NUM
clinmedi-182	95	57	(	(	PUNCT
clinmedi-182	95	58	03	03	NUM
clinmedi-182	95	59	)	)	PUNCT
clinmedi-182	95	60	,	,	PUNCT
clinmedi-182	95	61	415−429	415−429	PROPN
clinmedi-182	95	62	cmi	cmi	PROPN
clinmedi-182	95	63	journal	journal	PROPN
clinmedi-182	95	64	420	420	NUM
clinmedi-182	95	65	cmi	cmi	PROPN
clinmedi-182	95	66	journal	journal	PROPN
clinmedi-182	95	67	yasuaki	yasuaki	PROPN
clinmedi-182	95	68	nakagawa	nakagawa	PROPN
clinmedi-182	95	69	,	,	PUNCT
clinmedi-182	95	70	md	md	PROPN
clinmedi-182	95	71	joa	joa	PROPN
clinmedi-182	95	72	,	,	PUNCT
clinmedi-182	95	73	the	the	DET
clinmedi-182	95	74	japanese	japanese	ADJ
clinmedi-182	95	75	orthopedic	orthopedic	ADJ
clinmedi-182	95	76	association	association	PROPN
clinmedi-182	95	77	knee	knee	NOUN
clinmedi-182	95	78	scoring	scoring	NOUN
clinmedi-182	95	79	system	system	NOUN
clinmedi-182	95	80	;	;	PUNCT
clinmedi-182	95	81	jkom	jkom	NOUN
clinmedi-182	95	82	,	,	PUNCT
clinmedi-182	95	83	the	the	DET
clinmedi-182	95	84	japanese	japanese	ADJ
clinmedi-182	95	85	knee	knee	NOUN
clinmedi-182	95	86	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	95	87	measure	measure	NOUN
clinmedi-182	95	88	;	;	PUNCT
clinmedi-182	95	89	vas	vas	X
clinmedi-182	95	90	,	,	PUNCT
clinmedi-182	95	91	the	the	DET
clinmedi-182	95	92	knee	knee	NOUN
clinmedi-182	95	93	pain	pain	NOUN
clinmedi-182	95	94	visual	visual	ADJ
clinmedi-182	95	95	analogue	analogue	NOUN
clinmedi-182	95	96	scale	scale	NOUN
clinmedi-182	95	97	.	.	PUNCT
clinmedi-182	96	1	figure	figure	NOUN
clinmedi-182	96	2	2	2	NUM
clinmedi-182	96	3	depicts	depict	VERB
clinmedi-182	96	4	the	the	DET
clinmedi-182	96	5	blood	blood	NOUN
clinmedi-182	96	6	curcumin	curcumin	NOUN
clinmedi-182	96	7	concentrations	concentration	NOUN
clinmedi-182	96	8	,	,	PUNCT
clinmedi-182	96	9	with	with	ADP
clinmedi-182	96	10	mean	mean	ADJ
clinmedi-182	96	11	curcumin	curcumin	NOUN
clinmedi-182	96	12	concentration	concentration	NOUN
clinmedi-182	96	13	in	in	ADP
clinmedi-182	96	14	the	the	DET
clinmedi-182	96	15	high	high	ADV
clinmedi-182	96	16	-	-	PUNCT
clinmedi-182	96	17	dose	dose	NOUN
clinmedi-182	96	18	and	and	CCONJ
clinmedi-182	96	19	low	low	ADV
clinmedi-182	96	20	-	-	PUNCT
clinmedi-182	96	21	dose	dose	NOUN
clinmedi-182	96	22	curcurouge	curcurouge	NOUN
clinmedi-182	96	23	○	○	PROPN
clinmedi-182	96	24	r	r	NOUN
clinmedi-182	96	25	groups	group	NOUN
clinmedi-182	96	26	,	,	PUNCT
clinmedi-182	96	27	as	as	ADV
clinmedi-182	96	28	well	well	ADV
clinmedi-182	96	29	as	as	ADP
clinmedi-182	96	30	the	the	DET
clinmedi-182	96	31	placebo	placebo	NOUN
clinmedi-182	96	32	group	group	NOUN
clinmedi-182	96	33	,	,	PUNCT
clinmedi-182	96	34	at	at	ADP
clinmedi-182	96	35	12	12	NUM
clinmedi-182	96	36	weeks	week	NOUN
clinmedi-182	96	37	of	of	ADP
clinmedi-182	96	38	treatment	treatment	NOUN
clinmedi-182	96	39	being	be	AUX
clinmedi-182	96	40	199.6	199.6	NUM
clinmedi-182	96	41	,	,	PUNCT
clinmedi-182	96	42	79.1	79.1	NUM
clinmedi-182	96	43	,	,	PUNCT
clinmedi-182	96	44	and	and	CCONJ
clinmedi-182	96	45	0	0	NUM
clinmedi-182	96	46	ng	ng	NOUN
clinmedi-182	96	47	/	/	SYM
clinmedi-182	96	48	ml	ml	X
clinmedi-182	96	49	respectively	respectively	ADV
clinmedi-182	96	50	.	.	PUNCT
clinmedi-182	97	1	the	the	DET
clinmedi-182	97	2	highdose	highdose	PROPN
clinmedi-182	97	3	curcurouge	curcurouge	PROPN
clinmedi-182	97	4	○	○	PROPN
clinmedi-182	97	5	r	r	PROPN
clinmedi-182	97	6	group	group	NOUN
clinmedi-182	97	7	had	have	VERB
clinmedi-182	97	8	significantly	significantly	ADV
clinmedi-182	97	9	higher	high	ADJ
clinmedi-182	97	10	blood	blood	NOUN
clinmedi-182	97	11	curcumin	curcumin	NOUN
clinmedi-182	97	12	concentrations	concentration	NOUN
clinmedi-182	97	13	than	than	ADP
clinmedi-182	97	14	the	the	DET
clinmedi-182	97	15	low	low	ADV
clinmedi-182	97	16	-	-	PUNCT
clinmedi-182	97	17	dose	dose	NOUN
clinmedi-182	97	18	group	group	NOUN
clinmedi-182	97	19	.	.	PUNCT
clinmedi-182	98	1	figure	figure	NOUN
clinmedi-182	98	2	2	2	NUM
clinmedi-182	98	3	.	.	PUNCT
clinmedi-182	98	4	blood	blood	NOUN
clinmedi-182	98	5	curcumin	curcumin	NOUN
clinmedi-182	98	6	concentrations	concentration	NOUN
clinmedi-182	98	7	12	12	NUM
clinmedi-182	98	8	weeks	week	NOUN
clinmedi-182	98	9	after	after	ADP
clinmedi-182	98	10	treatment	treatment	NOUN
clinmedi-182	98	11	.	.	PUNCT
clinmedi-182	99	1	in	in	ADP
clinmedi-182	99	2	each	each	DET
clinmedi-182	99	3	group	group	NOUN
clinmedi-182	99	4	,	,	PUNCT
clinmedi-182	99	5	the	the	DET
clinmedi-182	99	6	joa	joa	NOUN
clinmedi-182	99	7	knee	knee	NOUN
clinmedi-182	99	8	oa	oa	PROPN
clinmedi-182	99	9	scores	score	NOUN
clinmedi-182	99	10	at	at	ADP
clinmedi-182	99	11	12	12	NUM
clinmedi-182	99	12	weeks	week	NOUN
clinmedi-182	99	13	were	be	AUX
clinmedi-182	99	14	significantly	significantly	ADV
clinmedi-182	99	15	higher	high	ADJ
clinmedi-182	99	16	than	than	ADP
clinmedi-182	99	17	those	those	PRON
clinmedi-182	99	18	at	at	ADP
clinmedi-182	99	19	0	0	NUM
clinmedi-182	99	20	weeks	week	NOUN
clinmedi-182	99	21	.	.	PUNCT
clinmedi-182	100	1	the	the	DET
clinmedi-182	100	2	changes	change	NOUN
clinmedi-182	100	3	in	in	ADP
clinmedi-182	100	4	joa	joa	PROPN
clinmedi-182	100	5	knee	knee	NOUN
clinmedi-182	100	6	oa	oa	PROPN
clinmedi-182	100	7	scores	score	NOUN
clinmedi-182	100	8	from	from	ADP
clinmedi-182	100	9	0	0	NUM
clinmedi-182	100	10	to	to	PART
clinmedi-182	100	11	12	12	NUM
clinmedi-182	100	12	weeks	week	NOUN
clinmedi-182	100	13	are	be	AUX
clinmedi-182	100	14	depicted	depict	VERB
clinmedi-182	100	15	in	in	ADP
clinmedi-182	100	16	figure	figure	NOUN
clinmedi-182	100	17	3a	3a	NUM
clinmedi-182	100	18	.	.	PUNCT
clinmedi-182	101	1	at	at	ADP
clinmedi-182	101	2	8	8	NUM
clinmedi-182	101	3	weeks	week	NOUN
clinmedi-182	101	4	,	,	PUNCT
clinmedi-182	101	5	the	the	DET
clinmedi-182	101	6	joa	joa	NOUN
clinmedi-182	101	7	score	score	NOUN
clinmedi-182	101	8	was	be	AUX
clinmedi-182	101	9	significantly	significantly	ADV
clinmedi-182	101	10	higher	high	ADJ
clinmedi-182	101	11	in	in	ADP
clinmedi-182	101	12	the	the	DET
clinmedi-182	101	13	high	high	ADJ
clinmedi-182	101	14	-	-	PUNCT
clinmedi-182	101	15	dose	dose	NOUN
clinmedi-182	101	16	curcurouge	curcurouge	NOUN
clinmedi-182	101	17	○	○	PROPN
clinmedi-182	101	18	r	r	NOUN
clinmedi-182	101	19	group	group	NOUN
clinmedi-182	101	20	than	than	ADP
clinmedi-182	101	21	in	in	ADP
clinmedi-182	101	22	the	the	DET
clinmedi-182	101	23	placebo	placebo	NOUN
clinmedi-182	101	24	group	group	NOUN
clinmedi-182	101	25	,	,	PUNCT
clinmedi-182	101	26	with	with	ADP
clinmedi-182	101	27	no	no	DET
clinmedi-182	101	28	significant	significant	ADJ
clinmedi-182	101	29	differences	difference	NOUN
clinmedi-182	101	30	among	among	ADP
clinmedi-182	101	31	the	the	DET
clinmedi-182	101	32	three	three	NUM
clinmedi-182	101	33	groups	group	NOUN
clinmedi-182	101	34	at	at	ADP
clinmedi-182	101	35	12	12	NUM
clinmedi-182	101	36	weeks	week	NOUN
clinmedi-182	101	37	.	.	PUNCT
clinmedi-182	102	1	in	in	ADP
clinmedi-182	102	2	addition	addition	NOUN
clinmedi-182	102	3	,	,	PUNCT
clinmedi-182	102	4	jkom	jkom	NOUN
clinmedi-182	102	5	scores	score	NOUN
clinmedi-182	102	6	at	at	ADP
clinmedi-182	102	7	12	12	NUM
clinmedi-182	102	8	weeks	week	NOUN
clinmedi-182	102	9	were	be	AUX
clinmedi-182	102	10	significantly	significantly	ADV
clinmedi-182	102	11	lower	low	ADJ
clinmedi-182	102	12	than	than	ADP
clinmedi-182	102	13	those	those	PRON
clinmedi-182	102	14	at	at	ADP
clinmedi-182	102	15	0	0	NUM
clinmedi-182	102	16	weeks	week	NOUN
clinmedi-182	102	17	in	in	ADP
clinmedi-182	102	18	the	the	DET
clinmedi-182	102	19	high	high	ADV
clinmedi-182	102	20	-	-	PUNCT
clinmedi-182	102	21	dose	dose	NOUN
clinmedi-182	102	22	curcurouge	curcurouge	NOUN
clinmedi-182	102	23	○	○	PROPN
clinmedi-182	102	24	r	r	NOUN
clinmedi-182	102	25	and	and	CCONJ
clinmedi-182	102	26	placebo	placebo	NOUN
clinmedi-182	102	27	groups	group	NOUN
clinmedi-182	102	28	,	,	PUNCT
clinmedi-182	102	29	with	with	ADP
clinmedi-182	102	30	no	no	DET
clinmedi-182	102	31	significant	significant	ADJ
clinmedi-182	102	32	differences	difference	NOUN
clinmedi-182	102	33	among	among	ADP
clinmedi-182	102	34	the	the	DET
clinmedi-182	102	35	three	three	NUM
clinmedi-182	102	36	groups	group	NOUN
clinmedi-182	102	37	.	.	PUNCT
clinmedi-182	103	1	furthermore	furthermore	ADV
clinmedi-182	103	2	,	,	PUNCT
clinmedi-182	103	3	vas	vas	X
clinmedi-182	103	4	scores	score	NOUN
clinmedi-182	103	5	at	at	ADP
clinmedi-182	103	6	12	12	NUM
clinmedi-182	103	7	weeks	week	NOUN
clinmedi-182	103	8	were	be	AUX
clinmedi-182	103	9	significantly	significantly	ADV
clinmedi-182	103	10	lower	low	ADJ
clinmedi-182	103	11	than	than	ADP
clinmedi-182	103	12	those	those	PRON
clinmedi-182	103	13	at	at	ADP
clinmedi-182	103	14	0	0	NUM
clinmedi-182	103	15	weeks	week	NOUN
clinmedi-182	103	16	in	in	ADP
clinmedi-182	103	17	all	all	DET
clinmedi-182	103	18	groups	group	NOUN
clinmedi-182	103	19	(	(	PUNCT
clinmedi-182	103	20	fig	fig	NOUN
clinmedi-182	103	21	.	.	PUNCT
clinmedi-182	104	1	3b	3b	NUM
clinmedi-182	104	2	)	)	PUNCT
clinmedi-182	104	3	,	,	PUNCT
clinmedi-182	104	4	with	with	ADP
clinmedi-182	104	5	no	no	DET
clinmedi-182	104	6	significant	significant	ADJ
clinmedi-182	104	7	differences	difference	NOUN
clinmedi-182	104	8	among	among	ADP
clinmedi-182	104	9	the	the	DET
clinmedi-182	104	10	three	three	NUM
clinmedi-182	104	11	groups	group	NOUN
clinmedi-182	104	12	.	.	PUNCT
clinmedi-182	105	1	the	the	DET
clinmedi-182	105	2	nsaid	nsaid	PROPN
clinmedi-182	105	3	need	need	VERB
clinmedi-182	105	4	ratio	ratio	NOUN
clinmedi-182	105	5	in	in	ADP
clinmedi-182	105	6	the	the	DET
clinmedi-182	105	7	three	three	NUM
clinmedi-182	105	8	groups	group	NOUN
clinmedi-182	105	9	is	be	AUX
clinmedi-182	105	10	depicted	depict	VERB
clinmedi-182	105	11	in	in	ADP
clinmedi-182	105	12	figure	figure	NOUN
clinmedi-182	105	13	3c	3c	NUM
clinmedi-182	105	14	.	.	PUNCT
clinmedi-182	106	1	the	the	DET
clinmedi-182	106	2	declining	decline	VERB
clinmedi-182	106	3	trend	trend	NOUN
clinmedi-182	106	4	in	in	ADP
clinmedi-182	106	5	the	the	DET
clinmedi-182	106	6	high	high	ADV
clinmedi-182	106	7	-	-	PUNCT
clinmedi-182	106	8	dose	dose	NOUN
clinmedi-182	106	9	curcurouge	curcurouge	NOUN
clinmedi-182	106	10	○	○	PROPN
clinmedi-182	106	11	r	r	PROPN
clinmedi-182	106	12	group	group	NOUN
clinmedi-182	106	13	was	be	AUX
clinmedi-182	106	14	significantly	significantly	ADV
clinmedi-182	106	15	greater	great	ADJ
clinmedi-182	106	16	than	than	ADP
clinmedi-182	106	17	that	that	PRON
clinmedi-182	106	18	in	in	ADP
clinmedi-182	106	19	the	the	DET
clinmedi-182	106	20	placebo	placebo	NOUN
clinmedi-182	106	21	group	group	NOUN
clinmedi-182	106	22	(	(	PUNCT
clinmedi-182	106	23	p<0.05	p<0.05	PROPN
clinmedi-182	106	24	)	)	PUNCT
clinmedi-182	106	25	,	,	PUNCT
clinmedi-182	106	26	with	with	ADP
clinmedi-182	106	27	respect	respect	NOUN
clinmedi-182	106	28	to	to	ADP
clinmedi-182	106	29	the	the	DET
clinmedi-182	106	30	approximate	approximate	ADJ
clinmedi-182	106	31	regression	regression	NOUN
clinmedi-182	106	32	line	line	NOUN
clinmedi-182	106	33	slope	slope	NOUN
clinmedi-182	106	34	.	.	PUNCT
clinmedi-182	107	1	cmi	cmi	PROPN
clinmedi-182	107	2	04	04	PROPN
clinmedi-182	107	3	(	(	PUNCT
clinmedi-182	107	4	03	03	NUM
clinmedi-182	107	5	)	)	PUNCT
clinmedi-182	107	6	,	,	PUNCT
clinmedi-182	107	7	415−429	415−429	PROPN
clinmedi-182	107	8	cmi	cmi	PROPN
clinmedi-182	107	9	journal	journal	PROPN
clinmedi-182	107	10	421	421	NUM
clinmedi-182	107	11	cmi	cmi	PROPN
clinmedi-182	107	12	journal	journal	PROPN
clinmedi-182	107	13	yasuaki	yasuaki	PROPN
clinmedi-182	107	14	nakagawa	nakagawa	PROPN
clinmedi-182	107	15	,	,	PUNCT
clinmedi-182	107	16	md	md	PROPN
clinmedi-182	107	17	points	point	NOUN
clinmedi-182	107	18	figure	figure	NOUN
clinmedi-182	107	19	3a	3a	NUM
clinmedi-182	107	20	.	.	PUNCT
clinmedi-182	108	1	improvement	improvement	NOUN
clinmedi-182	108	2	of	of	ADP
clinmedi-182	108	3	japanese	japanese	ADJ
clinmedi-182	108	4	orthopedic	orthopedic	ADJ
clinmedi-182	108	5	association	association	PROPN
clinmedi-182	108	6	(	(	PUNCT
clinmedi-182	108	7	joa	joa	NOUN
clinmedi-182	108	8	)	)	PUNCT
clinmedi-182	108	9	scores	score	NOUN
clinmedi-182	108	10	in	in	ADP
clinmedi-182	108	11	the	the	DET
clinmedi-182	108	12	studied	study	VERB
clinmedi-182	108	13	groups	group	NOUN
clinmedi-182	108	14	over	over	ADP
clinmedi-182	108	15	weeks	week	NOUN
clinmedi-182	108	16	.	.	PUNCT
clinmedi-182	109	1	points	point	NOUN
clinmedi-182	109	2	figure	figure	NOUN
clinmedi-182	109	3	.	.	PUNCT
clinmedi-182	110	1	3b	3b	NUM
clinmedi-182	110	2	improvement	improvement	NOUN
clinmedi-182	110	3	of	of	ADP
clinmedi-182	110	4	visual	visual	ADJ
clinmedi-182	110	5	analogue	analogue	NOUN
clinmedi-182	110	6	scale	scale	NOUN
clinmedi-182	110	7	(	(	PUNCT
clinmedi-182	110	8	vas	vas	NOUN
clinmedi-182	110	9	)	)	PUNCT
clinmedi-182	110	10	scores	score	NOUN
clinmedi-182	110	11	in	in	ADP
clinmedi-182	110	12	the	the	DET
clinmedi-182	110	13	studied	study	VERB
clinmedi-182	110	14	groups	group	NOUN
clinmedi-182	110	15	over	over	ADP
clinmedi-182	110	16	weeks	week	NOUN
clinmedi-182	110	17	.	.	PUNCT
clinmedi-182	111	1	-0.2	-0.2	NOUN
clinmedi-182	111	2	0	0	NUM
clinmedi-182	111	3	0.2	0.2	NUM
clinmedi-182	111	4	0.4	0.4	NUM
clinmedi-182	111	5	0.6	0.6	NUM
clinmedi-182	111	6	0.8	0.8	NUM
clinmedi-182	111	7	0	0	NUM
clinmedi-182	111	8	week	week	NOUN
clinmedi-182	111	9	2	2	NUM
clinmedi-182	111	10	weeks	week	NOUN
clinmedi-182	111	11	4	4	NUM
clinmedi-182	111	12	weeks	week	NOUN
clinmedi-182	111	13	6	6	NUM
clinmedi-182	111	14	weeks	week	NOUN
clinmedi-182	111	15	8	8	NUM
clinmedi-182	111	16	weeks	week	NOUN
clinmedi-182	111	17	10	10	NUM
clinmedi-182	111	18	weeks	week	NOUN
clinmedi-182	111	19	12	12	NUM
clinmedi-182	111	20	weeks	week	NOUN
clinmedi-182	111	21	improved	improve	VERB
clinmedi-182	111	22	vas	vas	PROPN
clinmedi-182	111	23	scores	score	NOUN
clinmedi-182	111	24	90	90	NUM
clinmedi-182	111	25	mg	mg	NUM
clinmedi-182	111	26	30	30	NUM
clinmedi-182	111	27	mg	mg	PROPN
clinmedi-182	111	28	placebo	placebo	NOUN
clinmedi-182	111	29	cmi	cmi	NOUN
clinmedi-182	111	30	04	04	NUM
clinmedi-182	111	31	(	(	PUNCT
clinmedi-182	111	32	03	03	NUM
clinmedi-182	111	33	)	)	PUNCT
clinmedi-182	111	34	,	,	PUNCT
clinmedi-182	111	35	415−429	415−429	PROPN
clinmedi-182	111	36	cmi	cmi	PROPN
clinmedi-182	111	37	journal	journal	PROPN
clinmedi-182	111	38	422	422	NUM
clinmedi-182	111	39	cmi	cmi	PROPN
clinmedi-182	111	40	journal	journal	PROPN
clinmedi-182	111	41	yasuaki	yasuaki	PROPN
clinmedi-182	111	42	nakagawa	nakagawa	PROPN
clinmedi-182	111	43	,	,	PUNCT
clinmedi-182	111	44	md	md	PROPN
clinmedi-182	111	45	%	%	NOUN
clinmedi-182	111	46	figure	figure	NOUN
clinmedi-182	111	47	.	.	PUNCT
clinmedi-182	112	1	3c	3c	NUM
clinmedi-182	112	2	nonsteroidal	nonsteroidal	ADJ
clinmedi-182	112	3	anti	anti	ADJ
clinmedi-182	112	4	-	-	ADJ
clinmedi-182	112	5	inflammatory	inflammatory	ADJ
clinmedi-182	112	6	drug	drug	NOUN
clinmedi-182	112	7	(	(	PUNCT
clinmedi-182	112	8	nsaid	nsaid	PROPN
clinmedi-182	112	9	)	)	PUNCT
clinmedi-182	112	10	need	need	VERB
clinmedi-182	112	11	ratio	ratio	NOUN
clinmedi-182	112	12	changes	change	NOUN
clinmedi-182	112	13	in	in	ADP
clinmedi-182	112	14	the	the	DET
clinmedi-182	112	15	studied	study	VERB
clinmedi-182	112	16	groups	group	NOUN
clinmedi-182	112	17	over	over	ADP
clinmedi-182	112	18	weeks	week	NOUN
clinmedi-182	112	19	.	.	PUNCT
clinmedi-182	113	1	the	the	DET
clinmedi-182	113	2	number	number	NOUN
clinmedi-182	113	3	of	of	ADP
clinmedi-182	113	4	gaits	gait	NOUN
clinmedi-182	113	5	in	in	ADP
clinmedi-182	113	6	tug	tug	NOUN
clinmedi-182	113	7	in	in	ADP
clinmedi-182	113	8	the	the	DET
clinmedi-182	113	9	three	three	NUM
clinmedi-182	113	10	groups	group	NOUN
clinmedi-182	113	11	is	be	AUX
clinmedi-182	113	12	depicted	depict	VERB
clinmedi-182	113	13	in	in	ADP
clinmedi-182	113	14	figure	figure	NOUN
clinmedi-182	113	15	4	4	NUM
clinmedi-182	113	16	.	.	PUNCT
clinmedi-182	114	1	the	the	DET
clinmedi-182	114	2	number	number	NOUN
clinmedi-182	114	3	of	of	ADP
clinmedi-182	114	4	gaits	gait	NOUN
clinmedi-182	114	5	at	at	ADP
clinmedi-182	114	6	12	12	NUM
clinmedi-182	114	7	weeks	week	NOUN
clinmedi-182	114	8	of	of	ADP
clinmedi-182	114	9	treatment	treatment	NOUN
clinmedi-182	114	10	was	be	AUX
clinmedi-182	114	11	significantly	significantly	ADV
clinmedi-182	114	12	lower	low	ADJ
clinmedi-182	114	13	than	than	ADP
clinmedi-182	114	14	that	that	PRON
clinmedi-182	114	15	at	at	ADP
clinmedi-182	114	16	0	0	NUM
clinmedi-182	114	17	weeks	week	NOUN
clinmedi-182	114	18	in	in	ADP
clinmedi-182	114	19	the	the	DET
clinmedi-182	114	20	high	high	ADV
clinmedi-182	114	21	-	-	PUNCT
clinmedi-182	114	22	dose	dose	NOUN
clinmedi-182	114	23	curcurouge	curcurouge	NOUN
clinmedi-182	114	24	○	○	PROPN
clinmedi-182	114	25	r	r	NOUN
clinmedi-182	114	26	group	group	NOUN
clinmedi-182	114	27	,	,	PUNCT
clinmedi-182	114	28	with	with	ADP
clinmedi-182	114	29	no	no	DET
clinmedi-182	114	30	significant	significant	ADJ
clinmedi-182	114	31	differences	difference	NOUN
clinmedi-182	114	32	among	among	ADP
clinmedi-182	114	33	the	the	DET
clinmedi-182	114	34	three	three	NUM
clinmedi-182	114	35	groups	group	NOUN
clinmedi-182	114	36	.	.	PUNCT
clinmedi-182	115	1	in	in	ADP
clinmedi-182	115	2	terms	term	NOUN
clinmedi-182	115	3	of	of	ADP
clinmedi-182	115	4	knee	knee	NOUN
clinmedi-182	115	5	rom	rom	NOUN
clinmedi-182	115	6	and	and	CCONJ
clinmedi-182	115	7	gait	gait	ADJ
clinmedi-182	115	8	time	time	NOUN
clinmedi-182	115	9	changes	change	NOUN
clinmedi-182	115	10	in	in	ADP
clinmedi-182	115	11	tug	tug	NOUN
clinmedi-182	115	12	,	,	PUNCT
clinmedi-182	115	13	there	there	PRON
clinmedi-182	115	14	were	be	VERB
clinmedi-182	115	15	no	no	DET
clinmedi-182	115	16	significant	significant	ADJ
clinmedi-182	115	17	differences	difference	NOUN
clinmedi-182	115	18	among	among	ADP
clinmedi-182	115	19	three	three	NUM
clinmedi-182	115	20	groups	group	NOUN
clinmedi-182	115	21	.	.	PUNCT
clinmedi-182	116	1	figure	figure	VERB
clinmedi-182	116	2	4	4	NUM
clinmedi-182	116	3	.	.	PUNCT
clinmedi-182	117	1	the	the	DET
clinmedi-182	117	2	number	number	NOUN
clinmedi-182	117	3	of	of	ADP
clinmedi-182	117	4	gaits	gait	NOUN
clinmedi-182	117	5	in	in	ADP
clinmedi-182	117	6	the	the	DET
clinmedi-182	117	7	timed	time	VERB
clinmedi-182	117	8	up	up	ADP
clinmedi-182	117	9	-	-	PUNCT
clinmedi-182	117	10	and	and	CCONJ
clinmedi-182	117	11	-	-	PUNCT
clinmedi-182	117	12	go	go	VERB
clinmedi-182	117	13	test	test	NOUN
clinmedi-182	117	14	(	(	PUNCT
clinmedi-182	117	15	tug	tug	NOUN
clinmedi-182	117	16	)	)	PUNCT
clinmedi-182	117	17	in	in	ADP
clinmedi-182	117	18	the	the	DET
clinmedi-182	117	19	studied	studied	ADJ
clinmedi-182	117	20	groups	group	NOUN
clinmedi-182	117	21	.	.	PUNCT
clinmedi-182	118	1	cmi	cmi	PROPN
clinmedi-182	118	2	04	04	PROPN
clinmedi-182	118	3	(	(	PUNCT
clinmedi-182	118	4	03	03	NUM
clinmedi-182	118	5	)	)	PUNCT
clinmedi-182	118	6	,	,	PUNCT
clinmedi-182	118	7	415−429	415−429	PROPN
clinmedi-182	118	8	cmi	cmi	PROPN
clinmedi-182	118	9	journal	journal	PROPN
clinmedi-182	118	10	423	423	NUM
clinmedi-182	118	11	cmi	cmi	PROPN
clinmedi-182	118	12	journal	journal	PROPN
clinmedi-182	118	13	yasuaki	yasuaki	PROPN
clinmedi-182	118	14	nakagawa	nakagawa	PROPN
clinmedi-182	118	15	,	,	PUNCT
clinmedi-182	118	16	md	md	PROPN
clinmedi-182	118	17	in	in	ADP
clinmedi-182	118	18	patients	patient	NOUN
clinmedi-182	118	19	with	with	ADP
clinmedi-182	118	20	kl	kl	PROPN
clinmedi-182	118	21	grade	grade	PROPN
clinmedi-182	118	22	ii	ii	PROPN
clinmedi-182	118	23	,	,	PUNCT
clinmedi-182	118	24	joa	joa	NOUN
clinmedi-182	118	25	score	score	NOUN
clinmedi-182	118	26	significantly	significantly	ADV
clinmedi-182	118	27	improved	improve	VERB
clinmedi-182	118	28	from	from	ADP
clinmedi-182	118	29	0	0	NUM
clinmedi-182	118	30	to	to	PART
clinmedi-182	118	31	12	12	NUM
clinmedi-182	118	32	weeks	week	NOUN
clinmedi-182	118	33	in	in	ADP
clinmedi-182	118	34	the	the	DET
clinmedi-182	118	35	high	high	ADV
clinmedi-182	118	36	-	-	PUNCT
clinmedi-182	118	37	dose	dose	NOUN
clinmedi-182	118	38	curcurouge	curcurouge	NOUN
clinmedi-182	118	39	○	○	PROPN
clinmedi-182	118	40	r	r	PROPN
clinmedi-182	118	41	group	group	NOUN
clinmedi-182	118	42	(	(	PUNCT
clinmedi-182	118	43	19.2±14.7	19.2±14.7	NUM
clinmedi-182	118	44	points	point	NOUN
clinmedi-182	118	45	)	)	PUNCT
clinmedi-182	118	46	more	more	ADJ
clinmedi-182	118	47	than	than	ADP
clinmedi-182	118	48	in	in	ADP
clinmedi-182	118	49	the	the	DET
clinmedi-182	118	50	placebo	placebo	NOUN
clinmedi-182	118	51	group	group	NOUN
clinmedi-182	118	52	(	(	PUNCT
clinmedi-182	118	53	4.5±8.9	4.5±8.9	NUM
clinmedi-182	118	54	points	point	VERB
clinmedi-182	118	55	)	)	PUNCT
clinmedi-182	118	56	(	(	PUNCT
clinmedi-182	118	57	fig	fig	NOUN
clinmedi-182	118	58	.	.	PUNCT
clinmedi-182	119	1	5a	5a	NUM
clinmedi-182	119	2	)	)	PUNCT
clinmedi-182	119	3	,	,	PUNCT
clinmedi-182	119	4	while	while	SCONJ
clinmedi-182	119	5	vas	vas	X
clinmedi-182	119	6	score	score	NOUN
clinmedi-182	119	7	was	be	AUX
clinmedi-182	119	8	significantly	significantly	ADV
clinmedi-182	119	9	reduced	reduce	VERB
clinmedi-182	119	10	(	(	PUNCT
clinmedi-182	119	11	high	high	ADV
clinmedi-182	119	12	-	-	PUNCT
clinmedi-182	119	13	dose	dose	NOUN
clinmedi-182	119	14	-0.36±0.18	-0.36±0.18	NOUN
clinmedi-182	119	15	,	,	PUNCT
clinmedi-182	119	16	placebo	placebo	NOUN
clinmedi-182	119	17	-0.01±0.22	-0.01±0.22	PROPN
clinmedi-182	119	18	)	)	PUNCT
clinmedi-182	119	19	(	(	PUNCT
clinmedi-182	119	20	fig	fig	NOUN
clinmedi-182	119	21	.	.	PUNCT
clinmedi-182	120	1	5b	5b	NUM
clinmedi-182	120	2	)	)	PUNCT
clinmedi-182	120	3	.	.	PUNCT
clinmedi-182	121	1	in	in	ADP
clinmedi-182	121	2	terms	term	NOUN
clinmedi-182	121	3	of	of	ADP
clinmedi-182	121	4	jkom	jkom	NOUN
clinmedi-182	121	5	scores	score	NOUN
clinmedi-182	121	6	,	,	PUNCT
clinmedi-182	121	7	rom	rom	NOUN
clinmedi-182	121	8	of	of	ADP
clinmedi-182	121	9	knee	knee	NOUN
clinmedi-182	121	10	joints	joint	NOUN
clinmedi-182	121	11	,	,	PUNCT
clinmedi-182	121	12	and	and	CCONJ
clinmedi-182	121	13	tug	tug	NOUN
clinmedi-182	121	14	gait	gait	ADJ
clinmedi-182	121	15	time	time	NOUN
clinmedi-182	121	16	,	,	PUNCT
clinmedi-182	121	17	there	there	PRON
clinmedi-182	121	18	were	be	VERB
clinmedi-182	121	19	no	no	DET
clinmedi-182	121	20	significant	significant	ADJ
clinmedi-182	121	21	differences	difference	NOUN
clinmedi-182	121	22	among	among	ADP
clinmedi-182	121	23	three	three	NUM
clinmedi-182	121	24	groups	group	NOUN
clinmedi-182	121	25	.	.	PUNCT
clinmedi-182	122	1	the	the	DET
clinmedi-182	122	2	number	number	NOUN
clinmedi-182	122	3	of	of	ADP
clinmedi-182	122	4	gaits	gait	NOUN
clinmedi-182	122	5	at	at	ADP
clinmedi-182	122	6	12	12	NUM
clinmedi-182	122	7	weeks	week	NOUN
clinmedi-182	122	8	of	of	ADP
clinmedi-182	122	9	treatment	treatment	NOUN
clinmedi-182	122	10	was	be	AUX
clinmedi-182	122	11	significantly	significantly	ADV
clinmedi-182	122	12	lower	low	ADJ
clinmedi-182	122	13	than	than	ADP
clinmedi-182	122	14	that	that	PRON
clinmedi-182	122	15	at	at	ADP
clinmedi-182	122	16	0	0	NUM
clinmedi-182	122	17	weeks	week	NOUN
clinmedi-182	122	18	in	in	ADP
clinmedi-182	122	19	the	the	DET
clinmedi-182	122	20	high	high	ADV
clinmedi-182	122	21	-	-	PUNCT
clinmedi-182	122	22	dose	dose	NOUN
clinmedi-182	122	23	curcurouge	curcurouge	NOUN
clinmedi-182	122	24	○	○	PROPN
clinmedi-182	122	25	r	r	NOUN
clinmedi-182	122	26	group	group	NOUN
clinmedi-182	122	27	,	,	PUNCT
clinmedi-182	122	28	with	with	ADP
clinmedi-182	122	29	no	no	DET
clinmedi-182	122	30	significant	significant	ADJ
clinmedi-182	122	31	differences	difference	NOUN
clinmedi-182	122	32	in	in	ADP
clinmedi-182	122	33	the	the	DET
clinmedi-182	122	34	other	other	ADJ
clinmedi-182	122	35	two	two	NUM
clinmedi-182	122	36	groups	group	NOUN
clinmedi-182	122	37	(	(	PUNCT
clinmedi-182	122	38	fig	fig	NOUN
clinmedi-182	122	39	.	.	PUNCT
clinmedi-182	122	40	5c	5c	NUM
clinmedi-182	122	41	)	)	PUNCT
clinmedi-182	122	42	.	.	PUNCT
clinmedi-182	123	1	figure	figure	VERB
clinmedi-182	123	2	5a	5a	NUM
clinmedi-182	123	3	.	.	PUNCT
clinmedi-182	124	1	improvement	improvement	NOUN
clinmedi-182	124	2	of	of	ADP
clinmedi-182	124	3	japanese	japanese	ADJ
clinmedi-182	124	4	orthopedic	orthopedic	ADJ
clinmedi-182	124	5	association	association	PROPN
clinmedi-182	124	6	(	(	PUNCT
clinmedi-182	124	7	joa	joa	NOUN
clinmedi-182	124	8	)	)	PUNCT
clinmedi-182	124	9	scores	score	NOUN
clinmedi-182	124	10	in	in	ADP
clinmedi-182	124	11	patients	patient	NOUN
clinmedi-182	124	12	with	with	ADP
clinmedi-182	124	13	kellgrenlawrence	kellgrenlawrence	PROPN
clinmedi-182	124	14	(	(	PUNCT
clinmedi-182	124	15	kl	kl	NOUN
clinmedi-182	124	16	)	)	PUNCT
clinmedi-182	124	17	grade	grade	NOUN
clinmedi-182	124	18	ii	ii	PROPN
clinmedi-182	124	19	in	in	ADP
clinmedi-182	124	20	the	the	DET
clinmedi-182	124	21	studied	study	VERB
clinmedi-182	124	22	groups	group	NOUN
clinmedi-182	124	23	.	.	PUNCT
clinmedi-182	125	1	figure	figure	NOUN
clinmedi-182	125	2	5b	5b	NUM
clinmedi-182	125	3	.	.	PUNCT
clinmedi-182	126	1	improvement	improvement	NOUN
clinmedi-182	126	2	of	of	ADP
clinmedi-182	126	3	visual	visual	ADJ
clinmedi-182	126	4	analogue	analogue	NOUN
clinmedi-182	126	5	scale	scale	NOUN
clinmedi-182	126	6	(	(	PUNCT
clinmedi-182	126	7	vas	vas	NOUN
clinmedi-182	126	8	)	)	PUNCT
clinmedi-182	126	9	scores	score	NOUN
clinmedi-182	126	10	in	in	ADP
clinmedi-182	126	11	patients	patient	NOUN
clinmedi-182	126	12	with	with	ADP
clinmedi-182	126	13	kellgren	kellgren	PROPN
clinmedi-182	126	14	-	-	PUNCT
clinmedi-182	126	15	lawrence	lawrence	PROPN
clinmedi-182	126	16	(	(	PUNCT
clinmedi-182	126	17	kl	kl	PROPN
clinmedi-182	126	18	)	)	PUNCT
clinmedi-182	126	19	grade	grade	NOUN
clinmedi-182	126	20	ii	ii	PROPN
clinmedi-182	126	21	in	in	ADP
clinmedi-182	126	22	the	the	DET
clinmedi-182	126	23	studied	study	VERB
clinmedi-182	126	24	groups	group	NOUN
clinmedi-182	126	25	.	.	PUNCT
clinmedi-182	127	1	cmi	cmi	PROPN
clinmedi-182	127	2	04	04	PROPN
clinmedi-182	127	3	(	(	PUNCT
clinmedi-182	127	4	03	03	NUM
clinmedi-182	127	5	)	)	PUNCT
clinmedi-182	127	6	,	,	PUNCT
clinmedi-182	127	7	415−429	415−429	PROPN
clinmedi-182	127	8	cmi	cmi	PROPN
clinmedi-182	127	9	journal	journal	PROPN
clinmedi-182	127	10	424	424	NUM
clinmedi-182	127	11	cmi	cmi	PROPN
clinmedi-182	127	12	journal	journal	PROPN
clinmedi-182	127	13	yasuaki	yasuaki	PROPN
clinmedi-182	127	14	nakagawa	nakagawa	PROPN
clinmedi-182	127	15	,	,	PUNCT
clinmedi-182	127	16	md	md	PROPN
clinmedi-182	127	17	figure	figure	VERB
clinmedi-182	127	18	5c	5c	NOUN
clinmedi-182	127	19	.	.	PUNCT
clinmedi-182	128	1	timed	time	VERB
clinmedi-182	128	2	up	up	ADP
clinmedi-182	128	3	-	-	PUNCT
clinmedi-182	128	4	and	and	CCONJ
clinmedi-182	128	5	-	-	PUNCT
clinmedi-182	128	6	go	go	VERB
clinmedi-182	128	7	test	test	NOUN
clinmedi-182	128	8	(	(	PUNCT
clinmedi-182	128	9	tug	tug	NOUN
clinmedi-182	128	10	)	)	PUNCT
clinmedi-182	128	11	gait	gait	ADJ
clinmedi-182	128	12	number	number	NOUN
clinmedi-182	128	13	in	in	ADP
clinmedi-182	128	14	patients	patient	NOUN
clinmedi-182	128	15	with	with	ADP
clinmedi-182	128	16	kellgren	kellgren	PROPN
clinmedi-182	128	17	-	-	PUNCT
clinmedi-182	128	18	lawrence	lawrence	PROPN
clinmedi-182	128	19	(	(	PUNCT
clinmedi-182	128	20	kl	kl	PROPN
clinmedi-182	128	21	)	)	PUNCT
clinmedi-182	128	22	grade	grade	NOUN
clinmedi-182	128	23	ii	ii	PROPN
clinmedi-182	128	24	in	in	ADP
clinmedi-182	128	25	the	the	DET
clinmedi-182	128	26	studied	study	VERB
clinmedi-182	128	27	groups	group	NOUN
clinmedi-182	128	28	.	.	PUNCT
clinmedi-182	129	1	in	in	ADP
clinmedi-182	129	2	patients	patient	NOUN
clinmedi-182	129	3	with	with	ADP
clinmedi-182	129	4	kl	kl	PROPN
clinmedi-182	129	5	grade	grade	PROPN
clinmedi-182	129	6	iii	iii	PROPN
clinmedi-182	129	7	,	,	PUNCT
clinmedi-182	129	8	there	there	PRON
clinmedi-182	129	9	were	be	VERB
clinmedi-182	129	10	no	no	DET
clinmedi-182	129	11	significant	significant	ADJ
clinmedi-182	129	12	differences	difference	NOUN
clinmedi-182	129	13	in	in	ADP
clinmedi-182	129	14	joa	joa	PROPN
clinmedi-182	129	15	,	,	PUNCT
clinmedi-182	129	16	jkom	jkom	NOUN
clinmedi-182	129	17	,	,	PUNCT
clinmedi-182	129	18	or	or	CCONJ
clinmedi-182	129	19	vas	vas	NOUN
clinmedi-182	129	20	scores	score	NOUN
clinmedi-182	129	21	,	,	PUNCT
clinmedi-182	129	22	as	as	ADV
clinmedi-182	129	23	well	well	ADV
clinmedi-182	129	24	as	as	ADP
clinmedi-182	129	25	rom	rom	NOUN
clinmedi-182	129	26	of	of	ADP
clinmedi-182	129	27	knee	knee	NOUN
clinmedi-182	129	28	joints	joint	NOUN
clinmedi-182	129	29	,	,	PUNCT
clinmedi-182	129	30	and	and	CCONJ
clinmedi-182	129	31	tug	tug	NOUN
clinmedi-182	129	32	gait	gait	ADJ
clinmedi-182	129	33	time	time	NOUN
clinmedi-182	129	34	and	and	CCONJ
clinmedi-182	129	35	number	number	NOUN
clinmedi-182	129	36	,	,	PUNCT
clinmedi-182	129	37	among	among	ADP
clinmedi-182	129	38	the	the	DET
clinmedi-182	129	39	three	three	NUM
clinmedi-182	129	40	groups	group	NOUN
clinmedi-182	129	41	.	.	PUNCT
clinmedi-182	130	1	at	at	ADP
clinmedi-182	130	2	12	12	NUM
clinmedi-182	130	3	weeks	week	NOUN
clinmedi-182	130	4	of	of	ADP
clinmedi-182	130	5	treatment	treatment	NOUN
clinmedi-182	130	6	,	,	PUNCT
clinmedi-182	130	7	all	all	DET
clinmedi-182	130	8	laboratory	laboratory	NOUN
clinmedi-182	130	9	results	result	NOUN
clinmedi-182	130	10	were	be	AUX
clinmedi-182	130	11	comparable	comparable	ADJ
clinmedi-182	130	12	to	to	AUX
clinmedi-182	130	13	baseline	baseline	VERB
clinmedi-182	130	14	values	value	NOUN
clinmedi-182	130	15	in	in	ADP
clinmedi-182	130	16	each	each	DET
clinmedi-182	130	17	groups	group	NOUN
clinmedi-182	130	18	,	,	PUNCT
clinmedi-182	130	19	except	except	SCONJ
clinmedi-182	130	20	in	in	ADP
clinmedi-182	130	21	some	some	DET
clinmedi-182	130	22	patients	patient	NOUN
clinmedi-182	130	23	in	in	ADP
clinmedi-182	130	24	each	each	DET
clinmedi-182	130	25	group	group	NOUN
clinmedi-182	130	26	for	for	ADP
clinmedi-182	130	27	slight	slight	ADJ
clinmedi-182	130	28	increases	increase	NOUN
clinmedi-182	130	29	in	in	ADP
clinmedi-182	130	30	triglyceride	triglyceride	ADJ
clinmedi-182	130	31	(	(	PUNCT
clinmedi-182	130	32	four	four	NUM
clinmedi-182	130	33	cases	case	NOUN
clinmedi-182	130	34	in	in	ADP
clinmedi-182	130	35	the	the	DET
clinmedi-182	130	36	high	high	ADJ
clinmedi-182	130	37	-	-	PUNCT
clinmedi-182	130	38	dose	dose	NOUN
clinmedi-182	130	39	group	group	NOUN
clinmedi-182	130	40	,	,	PUNCT
clinmedi-182	130	41	three	three	NUM
clinmedi-182	130	42	in	in	ADP
clinmedi-182	130	43	the	the	DET
clinmedi-182	130	44	low	low	ADJ
clinmedi-182	130	45	-	-	PUNCT
clinmedi-182	130	46	dose	dose	NOUN
clinmedi-182	130	47	group	group	NOUN
clinmedi-182	130	48	,	,	PUNCT
clinmedi-182	130	49	and	and	CCONJ
clinmedi-182	130	50	three	three	NUM
clinmedi-182	130	51	in	in	ADP
clinmedi-182	130	52	the	the	DET
clinmedi-182	130	53	placebo	placebo	NOUN
clinmedi-182	130	54	group	group	NOUN
clinmedi-182	130	55	)	)	PUNCT
clinmedi-182	130	56	,	,	PUNCT
clinmedi-182	130	57	blood	blood	NOUN
clinmedi-182	130	58	urea	urea	NOUN
clinmedi-182	130	59	nitrogen	nitrogen	NOUN
clinmedi-182	130	60	(	(	PUNCT
clinmedi-182	130	61	two	two	NUM
clinmedi-182	130	62	cases	case	NOUN
clinmedi-182	130	63	in	in	ADP
clinmedi-182	130	64	the	the	DET
clinmedi-182	130	65	high	high	ADJ
clinmedi-182	130	66	-	-	PUNCT
clinmedi-182	130	67	dose	dose	NOUN
clinmedi-182	130	68	group	group	NOUN
clinmedi-182	130	69	,	,	PUNCT
clinmedi-182	130	70	seven	seven	NUM
clinmedi-182	130	71	in	in	ADP
clinmedi-182	130	72	the	the	DET
clinmedi-182	130	73	low	low	ADJ
clinmedi-182	130	74	-	-	PUNCT
clinmedi-182	130	75	dose	dose	NOUN
clinmedi-182	130	76	group	group	NOUN
clinmedi-182	130	77	,	,	PUNCT
clinmedi-182	130	78	and	and	CCONJ
clinmedi-182	130	79	four	four	NUM
clinmedi-182	130	80	in	in	ADP
clinmedi-182	130	81	the	the	DET
clinmedi-182	130	82	placebo	placebo	NOUN
clinmedi-182	130	83	group	group	NOUN
clinmedi-182	130	84	)	)	PUNCT
clinmedi-182	130	85	,	,	PUNCT
clinmedi-182	130	86	uric	uric	ADJ
clinmedi-182	130	87	acid	acid	NOUN
clinmedi-182	130	88	(	(	PUNCT
clinmedi-182	130	89	three	three	NUM
clinmedi-182	130	90	cases	case	NOUN
clinmedi-182	130	91	in	in	ADP
clinmedi-182	130	92	the	the	DET
clinmedi-182	130	93	low	low	ADJ
clinmedi-182	130	94	-	-	PUNCT
clinmedi-182	130	95	dose	dose	NOUN
clinmedi-182	130	96	group	group	NOUN
clinmedi-182	130	97	and	and	CCONJ
clinmedi-182	130	98	one	one	NUM
clinmedi-182	130	99	in	in	ADP
clinmedi-182	130	100	the	the	DET
clinmedi-182	130	101	placebo	placebo	NOUN
clinmedi-182	130	102	group	group	NOUN
clinmedi-182	130	103	)	)	PUNCT
clinmedi-182	130	104	,	,	PUNCT
clinmedi-182	130	105	and	and	CCONJ
clinmedi-182	130	106	slight	slight	ADJ
clinmedi-182	130	107	decreases	decrease	NOUN
clinmedi-182	130	108	in	in	ADP
clinmedi-182	130	109	hematocrit	hematocrit	PROPN
clinmedi-182	130	110	(	(	PUNCT
clinmedi-182	130	111	three	three	NUM
clinmedi-182	130	112	cases	case	NOUN
clinmedi-182	130	113	in	in	ADP
clinmedi-182	130	114	the	the	DET
clinmedi-182	130	115	high	high	ADJ
clinmedi-182	130	116	-	-	PUNCT
clinmedi-182	130	117	dose	dose	NOUN
clinmedi-182	130	118	group	group	NOUN
clinmedi-182	130	119	,	,	PUNCT
clinmedi-182	130	120	two	two	NUM
clinmedi-182	130	121	in	in	ADP
clinmedi-182	130	122	the	the	DET
clinmedi-182	130	123	low	low	ADJ
clinmedi-182	130	124	-	-	PUNCT
clinmedi-182	130	125	dose	dose	NOUN
clinmedi-182	130	126	group	group	NOUN
clinmedi-182	130	127	,	,	PUNCT
clinmedi-182	130	128	and	and	CCONJ
clinmedi-182	130	129	three	three	NUM
clinmedi-182	130	130	in	in	ADP
clinmedi-182	130	131	the	the	DET
clinmedi-182	130	132	placebo	placebo	NOUN
clinmedi-182	130	133	group	group	NOUN
clinmedi-182	130	134	)	)	PUNCT
clinmedi-182	130	135	,	,	PUNCT
clinmedi-182	130	136	and	and	CCONJ
clinmedi-182	130	137	albumin	albumin	NOUN
clinmedi-182	130	138	(	(	PUNCT
clinmedi-182	130	139	five	five	NUM
clinmedi-182	130	140	cases	case	NOUN
clinmedi-182	130	141	in	in	ADP
clinmedi-182	130	142	the	the	DET
clinmedi-182	130	143	high	high	ADJ
clinmedi-182	130	144	-	-	PUNCT
clinmedi-182	130	145	dose	dose	NOUN
clinmedi-182	130	146	group	group	NOUN
clinmedi-182	130	147	,	,	PUNCT
clinmedi-182	130	148	two	two	NUM
clinmedi-182	130	149	in	in	ADP
clinmedi-182	130	150	the	the	DET
clinmedi-182	130	151	lowdose	lowdose	ADJ
clinmedi-182	130	152	group	group	NOUN
clinmedi-182	130	153	,	,	PUNCT
clinmedi-182	130	154	and	and	CCONJ
clinmedi-182	130	155	four	four	NUM
clinmedi-182	130	156	in	in	ADP
clinmedi-182	130	157	the	the	DET
clinmedi-182	130	158	placebo	placebo	NOUN
clinmedi-182	130	159	group	group	NOUN
clinmedi-182	130	160	)	)	PUNCT
clinmedi-182	130	161	levels	level	NOUN
clinmedi-182	130	162	.	.	PUNCT
clinmedi-182	131	1	these	these	PRON
clinmedi-182	131	2	were	be	AUX
clinmedi-182	131	3	all	all	PRON
clinmedi-182	131	4	minor	minor	ADJ
clinmedi-182	131	5	changes	change	NOUN
clinmedi-182	131	6	.	.	PUNCT
clinmedi-182	132	1	on	on	ADP
clinmedi-182	132	2	comparing	compare	VERB
clinmedi-182	132	3	the	the	DET
clinmedi-182	132	4	laboratory	laboratory	NOUN
clinmedi-182	132	5	results	result	NOUN
clinmedi-182	132	6	at	at	ADP
clinmedi-182	132	7	12	12	NUM
clinmedi-182	132	8	weeks	week	NOUN
clinmedi-182	132	9	of	of	ADP
clinmedi-182	132	10	treatment	treatment	NOUN
clinmedi-182	132	11	to	to	ADP
clinmedi-182	132	12	those	those	PRON
clinmedi-182	132	13	at	at	ADP
clinmedi-182	132	14	0	0	NUM
clinmedi-182	132	15	weeks	week	NOUN
clinmedi-182	132	16	,	,	PUNCT
clinmedi-182	132	17	only	only	ADV
clinmedi-182	132	18	highly	highly	ADV
clinmedi-182	132	19	sensitive	sensitive	ADJ
clinmedi-182	132	20	c	c	NOUN
clinmedi-182	132	21	-	-	ADJ
clinmedi-182	132	22	reactive	reactive	ADJ
clinmedi-182	132	23	protein	protein	NOUN
clinmedi-182	132	24	(	(	PUNCT
clinmedi-182	132	25	hs	hs	NOUN
clinmedi-182	132	26	-	-	PUNCT
clinmedi-182	132	27	crp	crp	NOUN
clinmedi-182	132	28	)	)	PUNCT
clinmedi-182	132	29	levels	level	NOUN
clinmedi-182	132	30	significantly	significantly	ADV
clinmedi-182	132	31	differed	differ	VERB
clinmedi-182	132	32	,	,	PUNCT
clinmedi-182	132	33	with	with	ADP
clinmedi-182	132	34	a	a	DET
clinmedi-182	132	35	greater	great	ADJ
clinmedi-182	132	36	reduction	reduction	NOUN
clinmedi-182	132	37	in	in	ADP
clinmedi-182	132	38	the	the	DET
clinmedi-182	132	39	high	high	ADJ
clinmedi-182	132	40	-	-	PUNCT
clinmedi-182	132	41	dose	dose	NOUN
clinmedi-182	132	42	group	group	NOUN
clinmedi-182	132	43	than	than	ADP
clinmedi-182	132	44	in	in	ADP
clinmedi-182	132	45	the	the	DET
clinmedi-182	132	46	placebo	placebo	NOUN
clinmedi-182	132	47	group	group	NOUN
clinmedi-182	132	48	(	(	PUNCT
clinmedi-182	132	49	p=0.0432	p=0.0432	PROPN
clinmedi-182	132	50	)	)	PUNCT
clinmedi-182	132	51	(	(	PUNCT
clinmedi-182	132	52	fig	fig	NOUN
clinmedi-182	132	53	.	.	PUNCT
clinmedi-182	133	1	6	6	NUM
clinmedi-182	133	2	)	)	PUNCT
clinmedi-182	133	3	.	.	PUNCT
clinmedi-182	134	1	table	table	NOUN
clinmedi-182	134	2	2	2	NUM
clinmedi-182	134	3	summarizes	summarize	NOUN
clinmedi-182	134	4	the	the	DET
clinmedi-182	134	5	adverse	adverse	ADJ
clinmedi-182	134	6	events	event	NOUN
clinmedi-182	134	7	that	that	PRON
clinmedi-182	134	8	occurred	occur	VERB
clinmedi-182	134	9	in	in	ADP
clinmedi-182	134	10	all	all	DET
clinmedi-182	134	11	groups	group	NOUN
clinmedi-182	134	12	during	during	ADP
clinmedi-182	134	13	this	this	DET
clinmedi-182	134	14	study	study	NOUN
clinmedi-182	134	15	.	.	PUNCT
clinmedi-182	135	1	according	accord	VERB
clinmedi-182	135	2	to	to	ADP
clinmedi-182	135	3	the	the	DET
clinmedi-182	135	4	study	study	NOUN
clinmedi-182	135	5	’s	’s	PART
clinmedi-182	135	6	safety	safety	NOUN
clinmedi-182	135	7	committee	committee	NOUN
clinmedi-182	135	8	,	,	PUNCT
clinmedi-182	135	9	all	all	PRON
clinmedi-182	135	10	of	of	ADP
clinmedi-182	135	11	the	the	DET
clinmedi-182	135	12	aforementioned	aforementioned	ADJ
clinmedi-182	135	13	adverse	adverse	ADJ
clinmedi-182	135	14	events	event	NOUN
clinmedi-182	135	15	were	be	AUX
clinmedi-182	135	16	unrelated	unrelated	ADJ
clinmedi-182	135	17	to	to	ADP
clinmedi-182	135	18	curcurouge	curcurouge	NOUN
clinmedi-182	135	19	○	○	PROPN
clinmedi-182	135	20	r	r	NOUN
clinmedi-182	135	21	or	or	CCONJ
clinmedi-182	135	22	the	the	DET
clinmedi-182	135	23	placebo	placebo	NOUN
clinmedi-182	135	24	.	.	PUNCT
clinmedi-182	136	1	cmi	cmi	PROPN
clinmedi-182	136	2	04	04	PROPN
clinmedi-182	136	3	(	(	PUNCT
clinmedi-182	136	4	03	03	NUM
clinmedi-182	136	5	)	)	PUNCT
clinmedi-182	136	6	,	,	PUNCT
clinmedi-182	136	7	415−429	415−429	PROPN
clinmedi-182	136	8	cmi	cmi	PROPN
clinmedi-182	136	9	journal	journal	PROPN
clinmedi-182	136	10	425	425	NUM
clinmedi-182	136	11	cmi	cmi	PROPN
clinmedi-182	136	12	journal	journal	PROPN
clinmedi-182	136	13	yasuaki	yasuaki	PROPN
clinmedi-182	136	14	nakagawa	nakagawa	PROPN
clinmedi-182	136	15	,	,	PUNCT
clinmedi-182	136	16	md	md	PROPN
clinmedi-182	136	17	figure	figure	VERB
clinmedi-182	136	18	6	6	NUM
clinmedi-182	136	19	.	.	PUNCT
clinmedi-182	137	1	reduction	reduction	NOUN
clinmedi-182	137	2	of	of	ADP
clinmedi-182	137	3	highly	highly	ADV
clinmedi-182	137	4	sensitive	sensitive	ADJ
clinmedi-182	137	5	c	c	NOUN
clinmedi-182	137	6	-	-	ADJ
clinmedi-182	137	7	reactive	reactive	ADJ
clinmedi-182	137	8	protein	protein	NOUN
clinmedi-182	137	9	levels	level	NOUN
clinmedi-182	137	10	at	at	ADP
clinmedi-182	137	11	three	three	NUM
clinmedi-182	137	12	months	month	NOUN
clinmedi-182	137	13	in	in	ADP
clinmedi-182	137	14	the	the	DET
clinmedi-182	137	15	studied	study	VERB
clinmedi-182	137	16	groups	group	NOUN
clinmedi-182	137	17	.	.	PUNCT
clinmedi-182	138	1	table	table	NOUN
clinmedi-182	138	2	2	2	NUM
clinmedi-182	138	3	.	.	PUNCT
clinmedi-182	138	4	adverse	adverse	ADJ
clinmedi-182	138	5	events	event	NOUN
clinmedi-182	138	6	in	in	ADP
clinmedi-182	138	7	the	the	DET
clinmedi-182	138	8	studied	study	VERB
clinmedi-182	138	9	groups	group	NOUN
clinmedi-182	138	10	occuring	occur	VERB
clinmedi-182	138	11	during	during	ADP
clinmedi-182	138	12	the	the	DET
clinmedi-182	138	13	study	study	NOUN
clinmedi-182	138	14	period	period	NOUN
clinmedi-182	138	15	.	.	PUNCT
clinmedi-182	139	1	curcurouge	curcurouge	NOUN
clinmedi-182	139	2	®	®	NOUN
clinmedi-182	139	3	90	90	NUM
clinmedi-182	139	4	mg	mg	NOUN
clinmedi-182	139	5	curcurouge	curcurouge	NOUN
clinmedi-182	139	6	®	®	NOUN
clinmedi-182	139	7	30	30	NUM
clinmedi-182	139	8	mg	mg	PROPN
clinmedi-182	139	9	placebo	placebo	NOUN
clinmedi-182	139	10	gastrointestinal	gastrointestinal	ADJ
clinmedi-182	139	11	disorders	disorder	NOUN
clinmedi-182	139	12	1	1	NUM
clinmedi-182	139	13	case	case	NOUN
clinmedi-182	139	14	2	2	NUM
clinmedi-182	139	15	cases	case	NOUN
clinmedi-182	139	16	1	1	NUM
clinmedi-182	139	17	case	case	NOUN
clinmedi-182	139	18	vertigo	vertigo	VERB
clinmedi-182	139	19	2	2	NUM
clinmedi-182	139	20	cases	case	NOUN
clinmedi-182	139	21	1	1	NUM
clinmedi-182	139	22	case	case	NOUN
clinmedi-182	139	23	0	0	NUM
clinmedi-182	139	24	cases	case	NOUN
clinmedi-182	139	25	diarrhea	diarrhea	NOUN
clinmedi-182	139	26	2	2	NUM
clinmedi-182	139	27	cases	case	NOUN
clinmedi-182	139	28	0	0	NUM
clinmedi-182	139	29	cases	case	NOUN
clinmedi-182	139	30	1	1	NUM
clinmedi-182	139	31	case	case	NOUN
clinmedi-182	139	32	lower	low	ADJ
clinmedi-182	139	33	limb	limb	NOUN
clinmedi-182	139	34	edema	edema	NOUN
clinmedi-182	139	35	2	2	NUM
clinmedi-182	139	36	cases	case	NOUN
clinmedi-182	139	37	1	1	NUM
clinmedi-182	139	38	case	case	NOUN
clinmedi-182	139	39	1	1	NUM
clinmedi-182	139	40	case	case	NOUN
clinmedi-182	139	41	itching	itch	VERB
clinmedi-182	139	42	1	1	NUM
clinmedi-182	139	43	case	case	NOUN
clinmedi-182	139	44	1	1	NUM
clinmedi-182	139	45	case	case	NOUN
clinmedi-182	140	1	1	1	NUM
clinmedi-182	140	2	case	case	NOUN
clinmedi-182	140	3	radial	radial	ADJ
clinmedi-182	140	4	nerve	nerve	NOUN
clinmedi-182	140	5	palsy	palsy	ADJ
clinmedi-182	140	6	0	0	NUM
clinmedi-182	140	7	cases	case	NOUN
clinmedi-182	140	8	0	0	NUM
clinmedi-182	140	9	cases	case	NOUN
clinmedi-182	140	10	1	1	NUM
clinmedi-182	140	11	case	case	NOUN
clinmedi-182	140	12	discussion	discussion	NOUN
clinmedi-182	140	13	in	in	ADP
clinmedi-182	140	14	this	this	DET
clinmedi-182	140	15	study	study	NOUN
clinmedi-182	140	16	,	,	PUNCT
clinmedi-182	140	17	we	we	PRON
clinmedi-182	140	18	revealed	reveal	VERB
clinmedi-182	140	19	that	that	SCONJ
clinmedi-182	140	20	blood	blood	NOUN
clinmedi-182	140	21	curcumin	curcumin	NOUN
clinmedi-182	140	22	concentrations	concentration	NOUN
clinmedi-182	140	23	were	be	AUX
clinmedi-182	140	24	significantly	significantly	ADV
clinmedi-182	140	25	higher	high	ADJ
clinmedi-182	140	26	in	in	ADP
clinmedi-182	140	27	the	the	DET
clinmedi-182	140	28	high	high	ADJ
clinmedi-182	140	29	-	-	PUNCT
clinmedi-182	140	30	dose	dose	NOUN
clinmedi-182	140	31	curcurouge	curcurouge	NOUN
clinmedi-182	140	32	○	○	PROPN
clinmedi-182	140	33	r	r	NOUN
clinmedi-182	140	34	than	than	ADP
clinmedi-182	140	35	in	in	ADP
clinmedi-182	140	36	the	the	DET
clinmedi-182	140	37	low	low	ADJ
clinmedi-182	140	38	-	-	PUNCT
clinmedi-182	140	39	dose	dose	NOUN
clinmedi-182	140	40	curcurouge	curcurouge	NOUN
clinmedi-182	140	41	○	○	PROPN
clinmedi-182	140	42	r	r	NOUN
clinmedi-182	140	43	group	group	NOUN
clinmedi-182	140	44	.	.	PUNCT
clinmedi-182	141	1	in	in	ADP
clinmedi-182	141	2	each	each	DET
clinmedi-182	141	3	group	group	NOUN
clinmedi-182	141	4	,	,	PUNCT
clinmedi-182	141	5	joa	joa	NOUN
clinmedi-182	141	6	knee	knee	NOUN
clinmedi-182	141	7	oa	oa	PROPN
clinmedi-182	141	8	scores	score	NOUN
clinmedi-182	141	9	12	12	NUM
clinmedi-182	141	10	weeks	week	NOUN
clinmedi-182	141	11	after	after	SCONJ
clinmedi-182	141	12	treatment	treatment	NOUN
clinmedi-182	141	13	were	be	AUX
clinmedi-182	141	14	significantly	significantly	ADV
clinmedi-182	141	15	higher	high	ADJ
clinmedi-182	141	16	and	and	CCONJ
clinmedi-182	141	17	vas	vas	NOUN
clinmedi-182	141	18	scores	score	NOUN
clinmedi-182	141	19	were	be	AUX
clinmedi-182	141	20	significantly	significantly	ADV
clinmedi-182	141	21	lower	low	ADJ
clinmedi-182	141	22	than	than	ADP
clinmedi-182	141	23	at	at	ADP
clinmedi-182	141	24	0	0	NUM
clinmedi-182	141	25	weeks	week	NOUN
clinmedi-182	141	26	.	.	PUNCT
clinmedi-182	142	1	the	the	DET
clinmedi-182	142	2	declining	decline	VERB
clinmedi-182	142	3	trend	trend	NOUN
clinmedi-182	142	4	of	of	ADP
clinmedi-182	142	5	nsaid	nsaid	PROPN
clinmedi-182	142	6	needs	need	NOUN
clinmedi-182	142	7	in	in	ADP
clinmedi-182	142	8	the	the	DET
clinmedi-182	142	9	high	high	ADJ
clinmedi-182	142	10	-	-	PUNCT
clinmedi-182	142	11	dose	dose	NOUN
clinmedi-182	142	12	group	group	NOUN
clinmedi-182	142	13	was	be	AUX
clinmedi-182	142	14	significantly	significantly	ADV
clinmedi-182	142	15	greater	great	ADJ
clinmedi-182	142	16	than	than	ADP
clinmedi-182	142	17	that	that	PRON
clinmedi-182	142	18	in	in	ADP
clinmedi-182	142	19	the	the	DET
clinmedi-182	142	20	placebo	placebo	NOUN
clinmedi-182	142	21	group	group	NOUN
clinmedi-182	142	22	(	(	PUNCT
clinmedi-182	142	23	p<0.05	p<0.05	PROPN
clinmedi-182	142	24	)	)	PUNCT
clinmedi-182	142	25	,	,	PUNCT
clinmedi-182	142	26	with	with	ADP
clinmedi-182	142	27	respect	respect	NOUN
clinmedi-182	142	28	to	to	ADP
clinmedi-182	142	29	the	the	DET
clinmedi-182	142	30	approximate	approximate	ADJ
clinmedi-182	142	31	regression	regression	NOUN
clinmedi-182	142	32	lineslope	lineslope	NOUN
clinmedi-182	142	33	.	.	PUNCT
clinmedi-182	143	1	only	only	ADV
clinmedi-182	143	2	in	in	ADP
clinmedi-182	143	3	the	the	DET
clinmedi-182	143	4	high	high	ADJ
clinmedi-182	143	5	-	-	PUNCT
clinmedi-182	143	6	dose	dose	NOUN
clinmedi-182	143	7	group	group	NOUN
clinmedi-182	143	8	,	,	PUNCT
clinmedi-182	143	9	tug	tug	NOUN
clinmedi-182	143	10	gait	gait	ADJ
clinmedi-182	143	11	number	number	NOUN
clinmedi-182	143	12	at	at	ADP
clinmedi-182	143	13	12	12	NUM
clinmedi-182	143	14	weeks	week	NOUN
clinmedi-182	143	15	decreased	decrease	VERB
clinmedi-182	143	16	significantly	significantly	ADV
clinmedi-182	143	17	compared	compare	VERB
clinmedi-182	143	18	with	with	ADP
clinmedi-182	143	19	0	0	NUM
clinmedi-182	143	20	weeks	week	NOUN
clinmedi-182	143	21	.	.	PUNCT
clinmedi-182	144	1	in	in	ADP
clinmedi-182	144	2	patients	patient	NOUN
clinmedi-182	144	3	with	with	ADP
clinmedi-182	144	4	kl	kl	PROPN
clinmedi-182	144	5	grade	grade	PROPN
clinmedi-182	144	6	ii	ii	PROPN
clinmedi-182	144	7	,	,	PUNCT
clinmedi-182	144	8	joa	joa	NOUN
clinmedi-182	144	9	and	and	CCONJ
clinmedi-182	144	10	vas	vas	NOUN
clinmedi-182	144	11	scores	score	NOUN
clinmedi-182	144	12	significantly	significantly	ADV
clinmedi-182	144	13	improved	improve	VERB
clinmedi-182	144	14	from	from	ADP
clinmedi-182	144	15	0	0	NUM
clinmedi-182	144	16	to	to	PART
clinmedi-182	144	17	12	12	NUM
clinmedi-182	144	18	weeks	week	NOUN
clinmedi-182	144	19	in	in	ADP
clinmedi-182	144	20	the	the	DET
clinmedi-182	144	21	high	high	ADJ
clinmedi-182	144	22	-	-	PUNCT
clinmedi-182	144	23	dose	dose	NOUN
clinmedi-182	144	24	group	group	NOUN
clinmedi-182	144	25	more	more	ADJ
clinmedi-182	144	26	than	than	ADP
clinmedi-182	144	27	in	in	ADP
clinmedi-182	144	28	the	the	DET
clinmedi-182	144	29	placebo	placebo	NOUN
clinmedi-182	144	30	group	group	NOUN
clinmedi-182	144	31	.	.	PUNCT
clinmedi-182	145	1	the	the	DET
clinmedi-182	145	2	reduction	reduction	NOUN
clinmedi-182	145	3	of	of	ADP
clinmedi-182	145	4	hscrp	hscrp	ADJ
clinmedi-182	145	5	levels	level	NOUN
clinmedi-182	145	6	was	be	AUX
clinmedi-182	145	7	significantly	significantly	ADV
clinmedi-182	145	8	greater	great	ADJ
clinmedi-182	145	9	in	in	ADP
clinmedi-182	145	10	the	the	DET
clinmedi-182	145	11	highdose	highdose	ADJ
clinmedi-182	145	12	group	group	NOUN
clinmedi-182	145	13	than	than	ADP
clinmedi-182	145	14	in	in	ADP
clinmedi-182	145	15	the	the	DET
clinmedi-182	145	16	placebo	placebo	NOUN
clinmedi-182	145	17	group	group	NOUN
clinmedi-182	145	18	(	(	PUNCT
clinmedi-182	145	19	p=0.0432	p=0.0432	PROPN
clinmedi-182	145	20	)	)	PUNCT
clinmedi-182	145	21	.	.	PUNCT
clinmedi-182	146	1	several	several	ADJ
clinmedi-182	146	2	adverse	adverse	ADJ
clinmedi-182	146	3	events	event	NOUN
clinmedi-182	146	4	occurred	occur	VERB
clinmedi-182	146	5	in	in	ADP
clinmedi-182	146	6	all	all	DET
clinmedi-182	146	7	groups	group	NOUN
clinmedi-182	146	8	during	during	ADP
clinmedi-182	146	9	this	this	DET
clinmedi-182	146	10	study	study	NOUN
clinmedi-182	146	11	,	,	PUNCT
clinmedi-182	146	12	but	but	CCONJ
clinmedi-182	146	13	the	the	DET
clinmedi-182	146	14	study	study	NOUN
clinmedi-182	146	15	’s	’s	PART
clinmedi-182	146	16	safety	safety	NOUN
clinmedi-182	146	17	committee	committee	PROPN
clinmedi-182	146	18	determined	determine	VERB
clinmedi-182	146	19	that	that	SCONJ
clinmedi-182	146	20	all	all	PRON
clinmedi-182	146	21	of	of	ADP
clinmedi-182	146	22	them	they	PRON
clinmedi-182	146	23	were	be	AUX
clinmedi-182	146	24	unrelated	unrelated	ADJ
clinmedi-182	146	25	to	to	ADP
clinmedi-182	146	26	curcurouge	curcurouge	NOUN
clinmedi-182	146	27	○	○	PROPN
clinmedi-182	146	28	r	r	NOUN
clinmedi-182	146	29	or	or	CCONJ
clinmedi-182	146	30	the	the	DET
clinmedi-182	146	31	placebo	placebo	NOUN
clinmedi-182	146	32	.	.	PUNCT
clinmedi-182	147	1	these	these	DET
clinmedi-182	147	2	results	result	NOUN
clinmedi-182	147	3	indicate	indicate	VERB
clinmedi-182	147	4	that	that	SCONJ
clinmedi-182	147	5	curcurouge	curcurouge	ADJ
clinmedi-182	147	6	®	®	NOUN
clinmedi-182	147	7	can	can	AUX
clinmedi-182	147	8	be	be	AUX
clinmedi-182	147	9	an	an	DET
clinmedi-182	147	10	effective	effective	ADJ
clinmedi-182	147	11	and	and	CCONJ
clinmedi-182	147	12	safe	safe	ADJ
clinmedi-182	147	13	treatment	treatment	NOUN
clinmedi-182	147	14	for	for	ADP
clinmedi-182	147	15	patients	patient	NOUN
clinmedi-182	147	16	with	with	ADP
clinmedi-182	147	17	oa	oa	NOUN
clinmedi-182	147	18	,	,	PUNCT
clinmedi-182	147	19	especially	especially	ADV
clinmedi-182	147	20	those	those	PRON
clinmedi-182	147	21	with	with	ADP
clinmedi-182	147	22	kl	kl	PROPN
clinmedi-182	147	23	grade	grade	PROPN
clinmedi-182	147	24	ii	ii	PROPN
clinmedi-182	147	25	.	.	PUNCT
clinmedi-182	148	1	cmi	cmi	PROPN
clinmedi-182	148	2	04	04	PROPN
clinmedi-182	148	3	(	(	PUNCT
clinmedi-182	148	4	03	03	NUM
clinmedi-182	148	5	)	)	PUNCT
clinmedi-182	148	6	,	,	PUNCT
clinmedi-182	148	7	415−429	415−429	PROPN
clinmedi-182	148	8	cmi	cmi	PROPN
clinmedi-182	148	9	journal	journal	PROPN
clinmedi-182	148	10	426	426	NUM
clinmedi-182	148	11	cmi	cmi	PROPN
clinmedi-182	148	12	journal	journal	PROPN
clinmedi-182	148	13	yasuaki	yasuaki	PROPN
clinmedi-182	148	14	nakagawa	nakagawa	PROPN
clinmedi-182	148	15	,	,	PUNCT
clinmedi-182	148	16	md	md	PROPN
clinmedi-182	148	17	curcumin	curcumin	PROPN
clinmedi-182	148	18	has	have	VERB
clinmedi-182	148	19	anti	anti	ADJ
clinmedi-182	148	20	-	-	ADJ
clinmedi-182	148	21	inflammatory	inflammatory	ADJ
clinmedi-182	148	22	as	as	ADV
clinmedi-182	148	23	well	well	ADV
clinmedi-182	148	24	as	as	ADP
clinmedi-182	148	25	antioxidative	antioxidative	ADJ
clinmedi-182	148	26	activities	activity	NOUN
clinmedi-182	148	27	and	and	CCONJ
clinmedi-182	148	28	is	be	AUX
clinmedi-182	148	29	expected	expect	VERB
clinmedi-182	148	30	as	as	ADP
clinmedi-182	148	31	a	a	DET
clinmedi-182	148	32	treatment	treatment	NOUN
clinmedi-182	148	33	of	of	ADP
clinmedi-182	148	34	osteoarticular	osteoarticular	ADJ
clinmedi-182	148	35	diseases	disease	NOUN
clinmedi-182	148	36	.	.	PUNCT
clinmedi-182	149	1	a	a	DET
clinmedi-182	149	2	high	high	ADJ
clinmedi-182	149	3	dose	dose	NOUN
clinmedi-182	149	4	of	of	ADP
clinmedi-182	149	5	standardized	standardized	ADJ
clinmedi-182	149	6	curcumin	curcumin	NOUN
clinmedi-182	149	7	extract	extract	NOUN
clinmedi-182	149	8	(	(	PUNCT
clinmedi-182	149	9	500	500	NUM
clinmedi-182	149	10	mg	mg	NOUN
clinmedi-182	149	11	twice	twice	ADV
clinmedi-182	149	12	daily	daily	ADV
clinmedi-182	149	13	)	)	PUNCT
clinmedi-182	149	14	was	be	AUX
clinmedi-182	149	15	reported	report	VERB
clinmedi-182	149	16	to	to	PART
clinmedi-182	149	17	associate	associate	VERB
clinmedi-182	149	18	with	with	ADP
clinmedi-182	149	19	the	the	DET
clinmedi-182	149	20	improvements	improvement	NOUN
clinmedi-182	149	21	on	on	ADP
clinmedi-182	149	22	the	the	DET
clinmedi-182	149	23	tug	tug	NOUN
clinmedi-182	149	24	,	,	PUNCT
clinmedi-182	149	25	six	six	NUM
clinmedi-182	149	26	-	-	PUNCT
clinmedi-182	149	27	minute	minute	NOUN
clinmedi-182	149	28	walk	walk	NOUN
clinmedi-182	149	29	test	test	NOUN
clinmedi-182	149	30	,	,	PUNCT
clinmedi-182	149	31	and	and	CCONJ
clinmedi-182	149	32	joa	joa	NOUN
clinmedi-182	149	33	total	total	ADJ
clinmedi-182	149	34	score	score	NOUN
clinmedi-182	149	35	in	in	ADP
clinmedi-182	149	36	oa	oa	ADP
clinmedi-182	149	37	patients	patient	NOUN
clinmedi-182	149	38	[	[	X
clinmedi-182	149	39	20	20	NUM
clinmedi-182	149	40	]	]	PUNCT
clinmedi-182	149	41	.	.	PUNCT
clinmedi-182	150	1	but	but	CCONJ
clinmedi-182	150	2	the	the	DET
clinmedi-182	150	3	doubts	doubt	NOUN
clinmedi-182	150	4	have	have	AUX
clinmedi-182	150	5	been	be	AUX
clinmedi-182	150	6	raised	raise	VERB
clinmedi-182	150	7	about	about	ADP
clinmedi-182	150	8	the	the	DET
clinmedi-182	150	9	ability	ability	NOUN
clinmedi-182	150	10	of	of	ADP
clinmedi-182	150	11	oral	oral	ADJ
clinmedi-182	150	12	curcumin	curcumin	NOUN
clinmedi-182	150	13	to	to	PART
clinmedi-182	150	14	reach	reach	VERB
clinmedi-182	150	15	pharmacologically	pharmacologically	ADV
clinmedi-182	150	16	active	active	ADJ
clinmedi-182	150	17	concentrations	concentration	NOUN
clinmedi-182	150	18	in	in	ADP
clinmedi-182	150	19	synovial	synovial	ADJ
clinmedi-182	150	20	fluid	fluid	NOUN
clinmedi-182	150	21	or	or	CCONJ
clinmedi-182	150	22	joint	joint	ADJ
clinmedi-182	150	23	tissues	tissue	NOUN
clinmedi-182	150	24	[	[	X
clinmedi-182	150	25	21	21	NUM
clinmedi-182	150	26	]	]	PUNCT
clinmedi-182	150	27	because	because	SCONJ
clinmedi-182	150	28	its	its	PRON
clinmedi-182	150	29	oral	oral	ADJ
clinmedi-182	150	30	bioavailability	bioavailability	NOUN
clinmedi-182	150	31	is	be	AUX
clinmedi-182	150	32	only	only	ADV
clinmedi-182	150	33	1	1	NUM
clinmedi-182	150	34	%	%	NOUN
clinmedi-182	150	35	[	[	X
clinmedi-182	150	36	22	22	NUM
clinmedi-182	150	37	]	]	PUNCT
clinmedi-182	150	38	.	.	PUNCT
clinmedi-182	151	1	in	in	ADP
clinmedi-182	151	2	the	the	DET
clinmedi-182	151	3	present	present	ADJ
clinmedi-182	151	4	study	study	NOUN
clinmedi-182	151	5	,	,	PUNCT
clinmedi-182	151	6	we	we	PRON
clinmedi-182	151	7	were	be	AUX
clinmedi-182	151	8	able	able	ADJ
clinmedi-182	151	9	to	to	PART
clinmedi-182	151	10	prove	prove	VERB
clinmedi-182	151	11	that	that	SCONJ
clinmedi-182	151	12	super	super	ADJ
clinmedi-182	151	13	-	-	ADJ
clinmedi-182	151	14	absorbable	absorbable	ADJ
clinmedi-182	151	15	curcumin	curcumin	NOUN
clinmedi-182	151	16	formulation	formulation	NOUN
clinmedi-182	151	17	,	,	PUNCT
clinmedi-182	151	18	curcurouge	curcurouge	ADJ
clinmedi-182	151	19	®	®	NOUN
clinmedi-182	151	20	,	,	PUNCT
clinmedi-182	151	21	improved	improve	VERB
clinmedi-182	151	22	symptoms	symptom	NOUN
clinmedi-182	151	23	including	include	VERB
clinmedi-182	151	24	pain	pain	NOUN
clinmedi-182	151	25	in	in	ADP
clinmedi-182	151	26	patients	patient	NOUN
clinmedi-182	151	27	with	with	ADP
clinmedi-182	151	28	kl	kl	PROPN
clinmedi-182	151	29	grade	grade	PROPN
clinmedi-182	151	30	ii	ii	PROPN
clinmedi-182	151	31	.	.	PUNCT
clinmedi-182	152	1	according	accord	VERB
clinmedi-182	152	2	to	to	ADP
clinmedi-182	152	3	the	the	DET
clinmedi-182	152	4	basic	basic	ADJ
clinmedi-182	152	5	research	research	NOUN
clinmedi-182	152	6	or	or	CCONJ
clinmedi-182	152	7	animal	animal	NOUN
clinmedi-182	152	8	models	model	NOUN
clinmedi-182	152	9	for	for	ADP
clinmedi-182	152	10	the	the	DET
clinmedi-182	152	11	relationship	relationship	NOUN
clinmedi-182	152	12	between	between	ADP
clinmedi-182	152	13	curcumin	curcumin	NOUN
clinmedi-182	152	14	and	and	CCONJ
clinmedi-182	152	15	oa	oa	INTJ
clinmedi-182	152	16	,	,	PUNCT
clinmedi-182	152	17	zeng	zeng	PROPN
clinmedi-182	152	18	reported	report	VERB
clinmedi-182	152	19	that	that	SCONJ
clinmedi-182	152	20	curcumin	curcumin	NOUN
clinmedi-182	152	21	could	could	AUX
clinmedi-182	152	22	reduce	reduce	VERB
clinmedi-182	152	23	synovial	synovial	ADJ
clinmedi-182	152	24	cell	cell	NOUN
clinmedi-182	152	25	viability	viability	NOUN
clinmedi-182	152	26	,	,	PUNCT
clinmedi-182	152	27	inhibit	inhibit	VERB
clinmedi-182	152	28	cell	cell	NOUN
clinmedi-182	152	29	proliferation	proliferation	NOUN
clinmedi-182	152	30	,	,	PUNCT
clinmedi-182	152	31	increase	increase	VERB
clinmedi-182	152	32	cell	cell	NOUN
clinmedi-182	152	33	apoptosis	apoptosis	NOUN
clinmedi-182	152	34	,	,	PUNCT
clinmedi-182	152	35	and	and	CCONJ
clinmedi-182	152	36	eventually	eventually	ADV
clinmedi-182	152	37	alleviate	alleviate	VERB
clinmedi-182	152	38	oa	oa	ADV
clinmedi-182	152	39	-	-	PUNCT
clinmedi-182	152	40	related	relate	VERB
clinmedi-182	152	41	inflammation	inflammation	NOUN
clinmedi-182	152	42	by	by	ADP
clinmedi-182	152	43	inhibiting	inhibit	VERB
clinmedi-182	152	44	matrix	matrix	NOUN
clinmedi-182	152	45	metalloproteinase	metalloproteinase	NOUN
clinmedi-182	152	46	(	(	PUNCT
clinmedi-182	152	47	mmp)-3	mmp)-3	PROPN
clinmedi-182	152	48	expression	expression	NOUN
clinmedi-182	152	49	[	[	X
clinmedi-182	152	50	23	23	NUM
clinmedi-182	152	51	]	]	PUNCT
clinmedi-182	152	52	.	.	PUNCT
clinmedi-182	153	1	nicoliche	nicoliche	PROPN
clinmedi-182	153	2	demonstrated	demonstrate	VERB
clinmedi-182	153	3	that	that	SCONJ
clinmedi-182	153	4	curcumin	curcumin	NOUN
clinmedi-182	153	5	treatment	treatment	NOUN
clinmedi-182	153	6	has	have	VERB
clinmedi-182	153	7	a	a	DET
clinmedi-182	153	8	protective	protective	ADJ
clinmedi-182	153	9	effect	effect	NOUN
clinmedi-182	153	10	on	on	ADP
clinmedi-182	153	11	cartilage	cartilage	NOUN
clinmedi-182	153	12	by	by	ADP
clinmedi-182	153	13	increasing	increase	VERB
clinmedi-182	153	14	ihh	ihh	PROPN
clinmedi-182	153	15	,	,	PUNCT
clinmedi-182	153	16	col2	col2	NOUN
clinmedi-182	153	17	,	,	PUNCT
clinmedi-182	153	18	and	and	CCONJ
clinmedi-182	153	19	sox-5	sox-5	ADJ
clinmedi-182	153	20	expressions	expression	NOUN
clinmedi-182	153	21	and	and	CCONJ
clinmedi-182	153	22	the	the	DET
clinmedi-182	153	23	number	number	NOUN
clinmedi-182	153	24	of	of	ADP
clinmedi-182	153	25	chondrocytes	chondrocyte	NOUN
clinmedi-182	153	26	,	,	PUNCT
clinmedi-182	153	27	without	without	ADP
clinmedi-182	153	28	affecting	affect	VERB
clinmedi-182	153	29	cartilage	cartilage	NOUN
clinmedi-182	153	30	thickness	thickness	NOUN
clinmedi-182	153	31	or	or	CCONJ
clinmedi-182	153	32	mmp-8	mmp-8	NUM
clinmedi-182	153	33	and	and	CCONJ
clinmedi-182	153	34	mmp-13	mmp-13	VERB
clinmedi-182	153	35	expressions	expression	NOUN
clinmedi-182	153	36	[	[	X
clinmedi-182	153	37	24	24	NUM
clinmedi-182	153	38	]	]	PUNCT
clinmedi-182	153	39	.	.	PUNCT
clinmedi-182	154	1	in	in	ADP
clinmedi-182	154	2	addition	addition	NOUN
clinmedi-182	154	3	,	,	PUNCT
clinmedi-182	154	4	curcuminoid	curcuminoid	ADJ
clinmedi-182	154	5	delivery	delivery	NOUN
clinmedi-182	154	6	via	via	ADP
clinmedi-182	154	7	hyaluronic	hyaluronic	ADJ
clinmedi-182	154	8	acids	acid	NOUN
clinmedi-182	154	9	/	/	SYM
clinmedi-182	154	10	chitosan	chitosan	NOUN
clinmedi-182	154	11	nanoparticles	nanoparticle	NOUN
clinmedi-182	154	12	suppressed	suppress	VERB
clinmedi-182	154	13	chondrocyte	chondrocyte	NOUN
clinmedi-182	154	14	apoptosis	apoptosis	NOUN
clinmedi-182	154	15	by	by	ADP
clinmedi-182	154	16	inactivating	inactivate	VERB
clinmedi-182	154	17	the	the	DET
clinmedi-182	154	18	nuclear	nuclear	ADJ
clinmedi-182	154	19	factor	factor	NOUN
clinmedi-182	154	20	-	-	PUNCT
clinmedi-182	154	21	kappa	kappa	PROPN
clinmedi-182	154	22	b	b	PROPN
clinmedi-182	154	23	(	(	PUNCT
clinmedi-182	154	24	nf	nf	PROPN
clinmedi-182	154	25	-	-	PUNCT
clinmedi-182	154	26	kb	kb	ADJ
clinmedi-182	154	27	)	)	PUNCT
clinmedi-182	154	28	pathway	pathway	NOUN
clinmedi-182	155	1	[	[	X
clinmedi-182	155	2	25	25	NUM
clinmedi-182	155	3	]	]	PUNCT
clinmedi-182	155	4	.	.	PUNCT
clinmedi-182	156	1	curcumin	curcumin	NOUN
clinmedi-182	156	2	might	might	AUX
clinmedi-182	156	3	have	have	VERB
clinmedi-182	156	4	the	the	DET
clinmedi-182	156	5	potential	potential	NOUN
clinmedi-182	156	6	to	to	PART
clinmedi-182	156	7	inhibit	inhibit	VERB
clinmedi-182	156	8	oa	oa	PROPN
clinmedi-182	156	9	development	development	NOUN
clinmedi-182	156	10	via	via	ADP
clinmedi-182	156	11	suppressing	suppress	VERB
clinmedi-182	156	12	nf	nf	PROPN
clinmedi-182	156	13	-	-	PUNCT
clinmedi-182	156	14	kb	kb	NOUN
clinmedi-182	156	15	/	/	SYM
clinmedi-182	156	16	hypoxia	hypoxia	NOUN
clinmedi-182	156	17	-	-	PUNCT
clinmedi-182	156	18	inducible	inducible	ADJ
clinmedi-182	156	19	factor	factor	NOUN
clinmedi-182	156	20	2α	2α	NOUN
clinmedi-182	156	21	pathway	pathway	NOUN
clinmedi-182	156	22	activation	activation	NOUN
clinmedi-182	156	23	[	[	X
clinmedi-182	156	24	26	26	NUM
clinmedi-182	156	25	]	]	PUNCT
clinmedi-182	156	26	.	.	PUNCT
clinmedi-182	157	1	moreover	moreover	ADV
clinmedi-182	157	2	,	,	PUNCT
clinmedi-182	157	3	in	in	ADP
clinmedi-182	157	4	the	the	DET
clinmedi-182	157	5	oa	oa	PROPN
clinmedi-182	157	6	rats	rat	NOUN
clinmedi-182	157	7	model	model	NOUN
clinmedi-182	157	8	,	,	PUNCT
clinmedi-182	157	9	nakahata	nakahata	PROPN
clinmedi-182	157	10	demonstrated	demonstrate	VERB
clinmedi-182	157	11	that	that	SCONJ
clinmedi-182	157	12	curcumin	curcumin	NOUN
clinmedi-182	157	13	monoglucuronide	monoglucuronide	PROPN
clinmedi-182	157	14	sodium	sodium	NOUN
clinmedi-182	157	15	salt	salt	NOUN
clinmedi-182	157	16	(	(	PUNCT
clinmedi-182	157	17	tbp1901	tbp1901	ADJ
clinmedi-182	157	18	)	)	PUNCT
clinmedi-182	157	19	injections	injection	NOUN
clinmedi-182	157	20	significantly	significantly	ADV
clinmedi-182	157	21	reduced	reduce	VERB
clinmedi-182	157	22	synovial	synovial	ADJ
clinmedi-182	157	23	inflammation	inflammation	NOUN
clinmedi-182	157	24	at	at	ADP
clinmedi-182	157	25	weeks	week	NOUN
clinmedi-182	157	26	1	1	NUM
clinmedi-182	157	27	and	and	CCONJ
clinmedi-182	157	28	2	2	NUM
clinmedi-182	157	29	as	as	ADV
clinmedi-182	157	30	well	well	ADV
clinmedi-182	157	31	as	as	ADP
clinmedi-182	157	32	tumor	tumor	NOUN
clinmedi-182	157	33	necrosis	necrosis	NOUN
clinmedi-182	157	34	factor	factor	NOUN
clinmedi-182	157	35	-	-	PUNCT
clinmedi-182	157	36	α	α	NOUN
clinmedi-182	157	37	expression	expression	NOUN
clinmedi-182	157	38	in	in	ADP
clinmedi-182	157	39	the	the	DET
clinmedi-182	157	40	articular	articular	ADJ
clinmedi-182	157	41	cartilage	cartilage	NOUN
clinmedi-182	157	42	at	at	ADP
clinmedi-182	157	43	week	week	NOUN
clinmedi-182	157	44	6	6	NUM
clinmedi-182	157	45	.	.	PUNCT
clinmedi-182	158	1	tbp1901	tbp1901	ADJ
clinmedi-182	158	2	injections	injection	NOUN
clinmedi-182	158	3	also	also	ADV
clinmedi-182	158	4	suppressed	suppress	VERB
clinmedi-182	158	5	articular	articular	ADJ
clinmedi-182	158	6	cartilage	cartilage	NOUN
clinmedi-182	158	7	damage	damage	NOUN
clinmedi-182	158	8	,	,	PUNCT
clinmedi-182	158	9	subchondral	subchondral	ADJ
clinmedi-182	158	10	bone	bone	NOUN
clinmedi-182	158	11	plate	plate	NOUN
clinmedi-182	158	12	thickening	thickening	NOUN
clinmedi-182	158	13	,	,	PUNCT
clinmedi-182	158	14	subchondral	subchondral	ADJ
clinmedi-182	158	15	bone	bone	NOUN
clinmedi-182	158	16	plate	plate	NOUN
clinmedi-182	158	17	perforation	perforation	NOUN
clinmedi-182	158	18	,	,	PUNCT
clinmedi-182	158	19	and	and	CCONJ
clinmedi-182	158	20	osteophyte	osteophyte	ADJ
clinmedi-182	158	21	formation	formation	NOUN
clinmedi-182	158	22	at	at	ADP
clinmedi-182	158	23	week	week	NOUN
clinmedi-182	158	24	10	10	NUM
clinmedi-182	159	1	[	[	X
clinmedi-182	159	2	27	27	NUM
clinmedi-182	159	3	]	]	PUNCT
clinmedi-182	159	4	.	.	PUNCT
clinmedi-182	160	1	tbp1901	tbp1901	PRON
clinmedi-182	160	2	intra	intra	ADJ
clinmedi-182	160	3	-	-	ADJ
clinmedi-182	160	4	articular	articular	ADJ
clinmedi-182	160	5	injections	injection	NOUN
clinmedi-182	160	6	suppressed	suppress	VERB
clinmedi-182	160	7	synovial	synovial	ADJ
clinmedi-182	160	8	inflammation	inflammation	NOUN
clinmedi-182	160	9	in	in	ADP
clinmedi-182	160	10	the	the	DET
clinmedi-182	160	11	acute	acute	ADJ
clinmedi-182	160	12	phase	phase	NOUN
clinmedi-182	160	13	of	of	ADP
clinmedi-182	160	14	posttraumatic	posttraumatic	ADJ
clinmedi-182	160	15	oa	oa	NOUN
clinmedi-182	160	16	in	in	ADP
clinmedi-182	160	17	destabilized	destabilize	VERB
clinmedi-182	160	18	medial	medial	ADJ
clinmedi-182	160	19	meniscus	meniscus	NOUN
clinmedi-182	160	20	rats	rat	NOUN
clinmedi-182	160	21	.	.	PUNCT
clinmedi-182	161	1	in	in	ADP
clinmedi-182	161	2	the	the	DET
clinmedi-182	161	3	chronic	chronic	ADJ
clinmedi-182	161	4	phase	phase	NOUN
clinmedi-182	161	5	,	,	PUNCT
clinmedi-182	161	6	tbp1901	tbp1901	NOUN
clinmedi-182	161	7	suppressed	suppress	VERB
clinmedi-182	161	8	articular	articular	ADJ
clinmedi-182	161	9	cartilage	cartilage	NOUN
clinmedi-182	161	10	damage	damage	NOUN
clinmedi-182	161	11	and	and	CCONJ
clinmedi-182	161	12	regulated	regulate	VERB
clinmedi-182	161	13	subchondral	subchondral	ADJ
clinmedi-182	161	14	bone	bone	NOUN
clinmedi-182	161	15	plate	plate	NOUN
clinmedi-182	161	16	changes	change	NOUN
clinmedi-182	161	17	[	[	X
clinmedi-182	161	18	27	27	NUM
clinmedi-182	161	19	]	]	PUNCT
clinmedi-182	161	20	.	.	PUNCT
clinmedi-182	162	1	therefore	therefore	ADV
clinmedi-182	162	2	,	,	PUNCT
clinmedi-182	162	3	curcumin	curcumin	PROPN
clinmedi-182	162	4	is	be	AUX
clinmedi-182	162	5	thought	think	VERB
clinmedi-182	162	6	to	to	PART
clinmedi-182	162	7	have	have	VERB
clinmedi-182	162	8	anti	anti	ADJ
clinmedi-182	162	9	-	-	ADJ
clinmedi-182	162	10	inflammatory	inflammatory	ADJ
clinmedi-182	162	11	and	and	CCONJ
clinmedi-182	162	12	chondroprotective	chondroprotective	ADJ
clinmedi-182	162	13	effects	effect	NOUN
clinmedi-182	162	14	in	in	ADP
clinmedi-182	162	15	the	the	DET
clinmedi-182	162	16	oa	oa	PROPN
clinmedi-182	162	17	model	model	NOUN
clinmedi-182	162	18	.	.	PUNCT
clinmedi-182	163	1	in	in	ADP
clinmedi-182	163	2	clinical	clinical	ADJ
clinmedi-182	163	3	study	study	NOUN
clinmedi-182	163	4	using	use	VERB
clinmedi-182	163	5	curcurouge	curcurouge	ADJ
clinmedi-182	163	6	®	®	NOUN
clinmedi-182	163	7	in	in	ADP
clinmedi-182	163	8	elderly	elderly	ADJ
clinmedi-182	163	9	volunteers	volunteer	NOUN
clinmedi-182	163	10	,	,	PUNCT
clinmedi-182	163	11	kishimoto	kishimoto	PROPN
clinmedi-182	163	12	demonstrated	demonstrate	VERB
clinmedi-182	163	13	that	that	SCONJ
clinmedi-182	163	14	curcurouge	curcurouge	ADJ
clinmedi-182	163	15	®	®	NOUN
clinmedi-182	163	16	administration	administration	NOUN
clinmedi-182	163	17	significantly	significantly	ADV
clinmedi-182	163	18	reduces	reduce	VERB
clinmedi-182	163	19	the	the	DET
clinmedi-182	163	20	neutrophil	neutrophil	NOUN
clinmedi-182	163	21	-	-	PUNCT
clinmedi-182	163	22	to	to	ADP
clinmedi-182	163	23	-	-	PUNCT
clinmedi-182	163	24	lymphocyte	lymphocyte	NOUN
clinmedi-182	163	25	ratio	ratio	NOUN
clinmedi-182	163	26	,	,	PUNCT
clinmedi-182	163	27	an	an	DET
clinmedi-182	163	28	indicator	indicator	NOUN
clinmedi-182	163	29	of	of	ADP
clinmedi-182	163	30	prognosis	prognosis	NOUN
clinmedi-182	163	31	in	in	ADP
clinmedi-182	163	32	cardiovascular	cardiovascular	ADJ
clinmedi-182	163	33	disease	disease	NOUN
clinmedi-182	163	34	,	,	PUNCT
clinmedi-182	163	35	cancer	cancer	NOUN
clinmedi-182	163	36	,	,	PUNCT
clinmedi-182	163	37	infectious	infectious	ADJ
clinmedi-182	163	38	diseases	disease	NOUN
clinmedi-182	163	39	,	,	PUNCT
clinmedi-182	163	40	and	and	CCONJ
clinmedi-182	163	41	aging	age	VERB
clinmedi-182	164	1	[	[	X
clinmedi-182	164	2	28	28	NUM
clinmedi-182	164	3	]	]	PUNCT
clinmedi-182	164	4	.	.	PUNCT
clinmedi-182	165	1	curcumin	curcumin	PROPN
clinmedi-182	165	2	's	's	PART
clinmedi-182	165	3	safety	safety	NOUN
clinmedi-182	165	4	has	have	AUX
clinmedi-182	165	5	been	be	AUX
clinmedi-182	165	6	reported	report	VERB
clinmedi-182	165	7	in	in	ADP
clinmedi-182	165	8	several	several	ADJ
clinmedi-182	165	9	studies	study	NOUN
clinmedi-182	165	10	.	.	PUNCT
clinmedi-182	166	1	in	in	ADP
clinmedi-182	166	2	this	this	DET
clinmedi-182	166	3	regard	regard	NOUN
clinmedi-182	166	4	,	,	PUNCT
clinmedi-182	166	5	bannuru	bannuru	NOUN
clinmedi-182	166	6	found	find	VERB
clinmedi-182	166	7	no	no	DET
clinmedi-182	166	8	differences	difference	NOUN
clinmedi-182	166	9	between	between	ADP
clinmedi-182	166	10	patients	patient	NOUN
clinmedi-182	166	11	receiving	receive	VERB
clinmedi-182	166	12	curcuminoids	curcuminoid	NOUN
clinmedi-182	166	13	and	and	CCONJ
clinmedi-182	166	14	those	those	PRON
clinmedi-182	166	15	receiving	receive	VERB
clinmedi-182	166	16	placebo	placebo	NOUN
clinmedi-182	166	17	in	in	ADP
clinmedi-182	166	18	the	the	DET
clinmedi-182	166	19	incidence	incidence	NOUN
clinmedi-182	166	20	of	of	ADP
clinmedi-182	166	21	treatment	treatment	NOUN
clinmedi-182	166	22	withdrawal	withdrawal	NOUN
clinmedi-182	166	23	due	due	ADP
clinmedi-182	166	24	to	to	ADP
clinmedi-182	166	25	adverse	adverse	ADJ
clinmedi-182	166	26	events	event	NOUN
clinmedi-182	166	27	[	[	X
clinmedi-182	166	28	29	29	NUM
clinmedi-182	166	29	]	]	PUNCT
clinmedi-182	166	30	.	.	PUNCT
clinmedi-182	167	1	according	accord	VERB
clinmedi-182	167	2	to	to	ADP
clinmedi-182	167	3	hsiao	hsiao	PROPN
clinmedi-182	167	4	's	's	PART
clinmedi-182	167	5	meta	meta	ADJ
clinmedi-182	167	6	-	-	PUNCT
clinmedi-182	167	7	analysis	analysis	NOUN
clinmedi-182	167	8	,	,	PUNCT
clinmedi-182	167	9	low	low	ADJ
clinmedi-182	167	10	-	-	PUNCT
clinmedi-182	167	11	dose	dose	NOUN
clinmedi-182	167	12	(	(	PUNCT
clinmedi-182	167	13	daily	daily	PROPN
clinmedi-182	167	14	dose	dose	VERB
clinmedi-182	167	15	<	<	PROPN
clinmedi-182	167	16	1,000	1,000	NUM
clinmedi-182	167	17	mg	mg	NUM
clinmedi-182	167	18	)	)	PUNCT
clinmedi-182	167	19	and	and	CCONJ
clinmedi-182	167	20	high	high	ADV
clinmedi-182	167	21	-	-	PUNCT
clinmedi-182	167	22	dose	dose	NOUN
clinmedi-182	167	23	(	(	PUNCT
clinmedi-182	167	24	daily	daily	ADV
clinmedi-182	167	25	dose	dose	VERB
clinmedi-182	167	26	≧1,000	≧1,000	PROPN
clinmedi-182	167	27	mg	mg	PROPN
clinmedi-182	167	28	)	)	PUNCT
clinmedi-182	167	29	curcuminoids	curcuminoid	NOUN
clinmedi-182	167	30	had	have	VERB
clinmedi-182	167	31	less	less	ADJ
clinmedi-182	167	32	adverse	adverse	ADJ
clinmedi-182	167	33	event	event	NOUN
clinmedi-182	167	34	rate	rate	NOUN
clinmedi-182	167	35	than	than	ADP
clinmedi-182	167	36	nsaids	nsaid	NOUN
clinmedi-182	167	37	in	in	ADP
clinmedi-182	167	38	knee	knee	NOUN
clinmedi-182	167	39	oa	oa	X
clinmedi-182	168	1	[	[	X
clinmedi-182	168	2	30	30	NUM
clinmedi-182	168	3	]	]	PUNCT
clinmedi-182	168	4	.	.	PUNCT
clinmedi-182	169	1	the	the	DET
clinmedi-182	169	2	limitations	limitation	NOUN
clinmedi-182	169	3	of	of	ADP
clinmedi-182	169	4	our	our	PRON
clinmedi-182	169	5	study	study	NOUN
clinmedi-182	169	6	were	be	AUX
clinmedi-182	169	7	the	the	DET
clinmedi-182	169	8	small	small	ADJ
clinmedi-182	169	9	number	number	NOUN
clinmedi-182	169	10	of	of	ADP
clinmedi-182	169	11	patients	patient	NOUN
clinmedi-182	169	12	(	(	PUNCT
clinmedi-182	169	13	n=90	n=90	NUM
clinmedi-182	169	14	)	)	PUNCT
clinmedi-182	169	15	and	and	CCONJ
clinmedi-182	169	16	the	the	DET
clinmedi-182	169	17	short	short	ADJ
clinmedi-182	169	18	treatment	treatment	NOUN
clinmedi-182	169	19	duration	duration	NOUN
clinmedi-182	169	20	(	(	PUNCT
clinmedi-182	169	21	12	12	NUM
clinmedi-182	169	22	weeks	week	NOUN
clinmedi-182	169	23	)	)	PUNCT
clinmedi-182	169	24	for	for	ADP
clinmedi-182	169	25	knee	knee	NOUN
clinmedi-182	169	26	oa	oa	INTJ
clinmedi-182	169	27	.	.	PUNCT
clinmedi-182	170	1	this	this	PRON
clinmedi-182	170	2	was	be	AUX
clinmedi-182	170	3	a	a	DET
clinmedi-182	170	4	pilot	pilot	NOUN
clinmedi-182	170	5	study	study	NOUN
clinmedi-182	170	6	to	to	PART
clinmedi-182	170	7	determine	determine	VERB
clinmedi-182	170	8	the	the	DET
clinmedi-182	170	9	effect	effect	NOUN
clinmedi-182	170	10	of	of	ADP
clinmedi-182	170	11	curcurouge	curcurouge	NOUN
clinmedi-182	170	12	○	○	NOUN
clinmedi-182	170	13	r	r	NOUN
clinmedi-182	170	14	on	on	ADP
clinmedi-182	170	15	knee	knee	NOUN
clinmedi-182	170	16	oa	oa	INTJ
clinmedi-182	170	17	,	,	PUNCT
clinmedi-182	170	18	but	but	CCONJ
clinmedi-182	170	19	we	we	PRON
clinmedi-182	170	20	were	be	AUX
clinmedi-182	170	21	able	able	ADJ
clinmedi-182	170	22	to	to	PART
clinmedi-182	170	23	observe	observe	VERB
clinmedi-182	170	24	significant	significant	ADJ
clinmedi-182	170	25	improvements	improvement	NOUN
clinmedi-182	170	26	in	in	ADP
clinmedi-182	170	27	joa	joa	PROPN
clinmedi-182	170	28	and	and	CCONJ
clinmedi-182	170	29	vas	vas	NOUN
clinmedi-182	170	30	scores	score	NOUN
clinmedi-182	170	31	,	,	PUNCT
clinmedi-182	170	32	nsaid	nsaid	PROPN
clinmedi-182	170	33	(	(	PUNCT
clinmedi-182	170	34	celecoxib	celecoxib	NOUN
clinmedi-182	170	35	)	)	PUNCT
clinmedi-182	170	36	needs	need	NOUN
clinmedi-182	170	37	,	,	PUNCT
clinmedi-182	170	38	and	and	CCONJ
clinmedi-182	170	39	tug	tug	NOUN
clinmedi-182	170	40	.	.	PUNCT
clinmedi-182	171	1	future	future	ADJ
clinmedi-182	171	2	studies	study	NOUN
clinmedi-182	171	3	may	may	AUX
clinmedi-182	171	4	on	on	ADP
clinmedi-182	171	5	a	a	DET
clinmedi-182	171	6	larger	large	ADJ
clinmedi-182	171	7	number	number	NOUN
clinmedi-182	171	8	of	of	ADP
clinmedi-182	171	9	patients	patient	NOUN
clinmedi-182	171	10	with	with	ADP
clinmedi-182	171	11	knee	knee	NOUN
clinmedi-182	171	12	oa	oa	NOUN
clinmedi-182	171	13	over	over	ADP
clinmedi-182	171	14	a	a	DET
clinmedi-182	171	15	longer	long	ADJ
clinmedi-182	171	16	duration	duration	NOUN
clinmedi-182	171	17	are	be	AUX
clinmedi-182	171	18	required	require	VERB
clinmedi-182	171	19	to	to	PART
clinmedi-182	171	20	validate	validate	VERB
clinmedi-182	171	21	our	our	PRON
clinmedi-182	171	22	findings	finding	NOUN
clinmedi-182	171	23	.	.	PUNCT
clinmedi-182	172	1	cmi	cmi	PROPN
clinmedi-182	172	2	04	04	PROPN
clinmedi-182	172	3	(	(	PUNCT
clinmedi-182	172	4	03	03	NUM
clinmedi-182	172	5	)	)	PUNCT
clinmedi-182	172	6	,	,	PUNCT
clinmedi-182	172	7	415−429	415−429	PROPN
clinmedi-182	172	8	cmi	cmi	PROPN
clinmedi-182	172	9	journal	journal	PROPN
clinmedi-182	172	10	427	427	NUM
clinmedi-182	172	11	cmi	cmi	PROPN
clinmedi-182	172	12	journal	journal	PROPN
clinmedi-182	172	13	yasuaki	yasuaki	PROPN
clinmedi-182	172	14	nakagawa	nakagawa	PROPN
clinmedi-182	172	15	,	,	PUNCT
clinmedi-182	172	16	md	md	PROPN
clinmedi-182	172	17	in	in	ADP
clinmedi-182	172	18	conclusion	conclusion	NOUN
clinmedi-182	172	19	,	,	PUNCT
clinmedi-182	172	20	curcurouge	curcurouge	PROPN
clinmedi-182	172	21	○	○	PROPN
clinmedi-182	172	22	r	r	NOUN
clinmedi-182	172	23	has	have	AUX
clinmedi-182	172	24	succeeded	succeed	VERB
clinmedi-182	172	25	in	in	ADP
clinmedi-182	172	26	proofing	proof	VERB
clinmedi-182	172	27	a	a	DET
clinmedi-182	172	28	potential	potential	NOUN
clinmedi-182	172	29	for	for	ADP
clinmedi-182	172	30	treating	treat	VERB
clinmedi-182	172	31	human	human	ADJ
clinmedi-182	172	32	knee	knee	NOUN
clinmedi-182	172	33	oa	oa	INTJ
clinmedi-182	172	34	,	,	PUNCT
clinmedi-182	172	35	particularly	particularly	ADV
clinmedi-182	172	36	at	at	ADP
clinmedi-182	172	37	an	an	DET
clinmedi-182	172	38	early	early	ADJ
clinmedi-182	172	39	stage	stage	NOUN
clinmedi-182	172	40	.	.	PUNCT
clinmedi-182	173	1	acknowledgments	acknowledgment	NOUN
clinmedi-182	173	2	we	we	PRON
clinmedi-182	173	3	thank	thank	VERB
clinmedi-182	173	4	mr	mr	PROPN
clinmedi-182	173	5	.	.	PROPN
clinmedi-182	173	6	atsushi	atsushi	PROPN
clinmedi-182	173	7	imaizumi	imaizumi	PROPN
clinmedi-182	173	8	and	and	CCONJ
clinmedi-182	173	9	mr	mr	PROPN
clinmedi-182	173	10	.	.	PROPN
clinmedi-182	173	11	atsuhiro	atsuhiro	PROPN
clinmedi-182	173	12	kishimoto	kishimoto	PROPN
clinmedi-182	173	13	for	for	ADP
clinmedi-182	173	14	technical	technical	ADJ
clinmedi-182	173	15	assistance	assistance	NOUN
clinmedi-182	173	16	.	.	PUNCT
clinmedi-182	174	1	conflict	conflict	NOUN
clinmedi-182	174	2	of	of	ADP
clinmedi-182	174	3	interests	interest	NOUN
clinmedi-182	174	4	financial	financial	ADJ
clinmedi-182	174	5	support	support	NOUN
clinmedi-182	174	6	and	and	CCONJ
clinmedi-182	174	7	potential	potential	ADJ
clinmedi-182	174	8	conflicts	conflict	NOUN
clinmedi-182	174	9	of	of	ADP
clinmedi-182	174	10	interest	interest	NOUN
clinmedi-182	174	11	of	of	ADP
clinmedi-182	174	12	our	our	PRON
clinmedi-182	174	13	article	article	NOUN
clinmedi-182	174	14	is	be	AUX
clinmedi-182	174	15	in	in	ADP
clinmedi-182	174	16	the	the	DET
clinmedi-182	174	17	following	following	NOUN
clinmedi-182	174	18	:	:	PUNCT
clinmedi-182	174	19	this	this	DET
clinmedi-182	174	20	research	research	NOUN
clinmedi-182	174	21	was	be	AUX
clinmedi-182	174	22	financially	financially	ADV
clinmedi-182	174	23	supported	support	VERB
clinmedi-182	174	24	by	by	ADP
clinmedi-182	174	25	therabiopharma	therabiopharma	NOUN
clinmedi-182	174	26	corporation	corporation	PROPN
clinmedi-182	174	27	(	(	PUNCT
clinmedi-182	174	28	kanagawa	kanagawa	PROPN
clinmedi-182	174	29	,	,	PUNCT
clinmedi-182	174	30	japan	japan	PROPN
clinmedi-182	174	31	)	)	PUNCT
clinmedi-182	174	32	.	.	PUNCT
clinmedi-182	175	1	the	the	DET
clinmedi-182	175	2	authors	author	NOUN
clinmedi-182	175	3	declare	declare	VERB
clinmedi-182	175	4	that	that	SCONJ
clinmedi-182	175	5	there	there	PRON
clinmedi-182	175	6	is	be	VERB
clinmedi-182	175	7	no	no	DET
clinmedi-182	175	8	conflict	conflict	NOUN
clinmedi-182	175	9	of	of	ADP
clinmedi-182	175	10	interest	interest	NOUN
clinmedi-182	175	11	except	except	SCONJ
clinmedi-182	175	12	the	the	DET
clinmedi-182	175	13	above	above	ADJ
clinmedi-182	175	14	.	.	PUNCT
clinmedi-182	176	1	references	reference	NOUN
clinmedi-182	176	2	1	1	NUM
clinmedi-182	176	3	.	.	PUNCT
clinmedi-182	176	4	grazio	grazio	PROPN
clinmedi-182	176	5	s	s	PART
clinmedi-182	176	6	,	,	PUNCT
clinmedi-182	176	7	balen	balen	PROPN
clinmedi-182	176	8	d.	d.	PROPN
clinmedi-182	176	9	obesity	obesity	NOUN
clinmedi-182	176	10	:	:	PUNCT
clinmedi-182	176	11	risk	risk	NOUN
clinmedi-182	176	12	factor	factor	NOUN
clinmedi-182	176	13	and	and	CCONJ
clinmedi-182	176	14	predictor	predictor	NOUN
clinmedi-182	176	15	of	of	ADP
clinmedi-182	176	16	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	176	17	.	.	PUNCT
clinmedi-182	177	1	lijec	lijec	NOUN
clinmedi-182	177	2	vjest	vj	ADJ
clinmedi-182	177	3	.	.	PUNCT
clinmedi-182	178	1	2009	2009	NUM
clinmedi-182	178	2	;	;	PUNCT
clinmedi-182	178	3	131	131	NUM
clinmedi-182	178	4	:	:	SYM
clinmedi-182	178	5	22	22	NUM
clinmedi-182	178	6	-	-	SYM
clinmedi-182	178	7	26	26	NUM
clinmedi-182	178	8	2	2	NUM
clinmedi-182	178	9	.	.	PUNCT
clinmedi-182	179	1	smalley	smalley	PROPN
clinmedi-182	179	2	we	we	PRON
clinmedi-182	179	3	,	,	PUNCT
clinmedi-182	179	4	ray	ray	PROPN
clinmedi-182	179	5	wa	wa	PROPN
clinmedi-182	179	6	,	,	PUNCT
clinmedi-182	179	7	daugherty	daugherty	PROPN
clinmedi-182	179	8	jr	jr	PROPN
clinmedi-182	179	9	,	,	PUNCT
clinmedi-182	179	10	griffin	griffin	PROPN
clinmedi-182	179	11	mr	mr	PROPN
clinmedi-182	179	12	.	.	PROPN
clinmedi-182	179	13	nonsteroidal	nonsteroidal	NOUN
clinmedi-182	179	14	anti	anti	ADJ
clinmedi-182	179	15	-	-	ADJ
clinmedi-182	179	16	inflammatory	inflammatory	ADJ
clinmedi-182	179	17	drugs	drug	NOUN
clinmedi-182	179	18	and	and	CCONJ
clinmedi-182	179	19	the	the	DET
clinmedi-182	179	20	incidence	incidence	NOUN
clinmedi-182	179	21	of	of	ADP
clinmedi-182	179	22	hospitalizations	hospitalization	NOUN
clinmedi-182	179	23	for	for	ADP
clinmedi-182	179	24	peptic	peptic	ADJ
clinmedi-182	179	25	ulcer	ulcer	NOUN
clinmedi-182	179	26	diseases	disease	NOUN
clinmedi-182	179	27	in	in	ADP
clinmedi-182	179	28	elderly	elderly	ADJ
clinmedi-182	179	29	persons	person	NOUN
clinmedi-182	179	30	.	.	PUNCT
clinmedi-182	180	1	am	be	AUX
clinmedi-182	180	2	j	j	PROPN
clinmedi-182	180	3	epidemiol	epidemiol	PROPN
clinmedi-182	180	4	1995;141:539	1995;141:539	NUM
clinmedi-182	180	5	-	-	SYM
clinmedi-182	180	6	45	45	NUM
clinmedi-182	180	7	3	3	NUM
clinmedi-182	180	8	.	.	PUNCT
clinmedi-182	180	9	felson	felson	PROPN
clinmedi-182	180	10	dt	dt	PROPN
clinmedi-182	180	11	,	,	PUNCT
clinmedi-182	180	12	lawrence	lawrence	PROPN
clinmedi-182	180	13	rc	rc	PROPN
clinmedi-182	180	14	,	,	PUNCT
clinmedi-182	180	15	hochberg	hochberg	PROPN
clinmedi-182	180	16	mc	mc	PROPN
clinmedi-182	180	17	,	,	PUNCT
clinmedi-182	180	18	mcalindon	mcalindon	PROPN
clinmedi-182	180	19	t	t	PROPN
clinmedi-182	180	20	,	,	PUNCT
clinmedi-182	180	21	dieppe	dieppe	PROPN
clinmedi-182	180	22	pa	pa	PROPN
clinmedi-182	180	23	,	,	PUNCT
clinmedi-182	180	24	minor	minor	ADJ
clinmedi-182	180	25	ma	ma	PROPN
clinmedi-182	180	26	et	et	PROPN
clinmedi-182	180	27	al	al	PROPN
clinmedi-182	180	28	.	.	PUNCT
clinmedi-182	181	1	osteoarthritis	osteoarthritis	PROPN
clinmedi-182	181	2	:	:	PUNCT
clinmedi-182	181	3	new	new	ADJ
clinmedi-182	181	4	insights	insight	NOUN
clinmedi-182	181	5	,	,	PUNCT
clinmedi-182	181	6	part	part	NOUN
clinmedi-182	181	7	2	2	NUM
clinmedi-182	181	8	:	:	PUNCT
clinmedi-182	181	9	treatment	treatment	NOUN
clinmedi-182	181	10	approaches	approach	NOUN
clinmedi-182	181	11	.	.	PUNCT
clinmedi-182	182	1	ann	ann	PROPN
clinmedi-182	182	2	intern	intern	PROPN
clinmedi-182	182	3	med	med	PROPN
clinmedi-182	182	4	2000;133:726	2000;133:726	PROPN
clinmedi-182	182	5	-	-	SYM
clinmedi-182	182	6	37	37	NUM
clinmedi-182	182	7	4	4	NUM
clinmedi-182	182	8	.	.	PUNCT
clinmedi-182	183	1	goel	goel	PROPN
clinmedi-182	183	2	a	a	PROPN
clinmedi-182	183	3	,	,	PUNCT
clinmedi-182	183	4	kunnumakkara	kunnumakkara	PROPN
clinmedi-182	183	5	ab	ab	PROPN
clinmedi-182	183	6	,	,	PUNCT
clinmedi-182	183	7	aggarwal	aggarwal	PROPN
clinmedi-182	183	8	bb	bb	PROPN
clinmedi-182	183	9	.	.	PUNCT
clinmedi-182	183	10	curcumin	curcumin	PROPN
clinmedi-182	183	11	as	as	ADP
clinmedi-182	183	12	“	"	PUNCT
clinmedi-182	183	13	curecumin	curecumin	ADJ
clinmedi-182	183	14	”	"	PUNCT
clinmedi-182	183	15	:	:	PUNCT
clinmedi-182	183	16	from	from	ADP
clinmedi-182	183	17	kitchen	kitchen	NOUN
clinmedi-182	183	18	to	to	ADP
clinmedi-182	183	19	clinic	clinic	NOUN
clinmedi-182	183	20	.	.	PUNCT
clinmedi-182	184	1	biochem	biochem	PROPN
clinmedi-182	184	2	pharmacol	pharmacol	PROPN
clinmedi-182	184	3	2008;75:787	2008;75:787	PROPN
clinmedi-182	184	4	-	-	PUNCT
clinmedi-182	184	5	809	809	NUM
clinmedi-182	184	6	5	5	NUM
clinmedi-182	184	7	.	.	PUNCT
clinmedi-182	185	1	gupta	gupta	PROPN
clinmedi-182	185	2	sc	sc	PROPN
clinmedi-182	185	3	,	,	PUNCT
clinmedi-182	185	4	patchva	patchva	PROPN
clinmedi-182	185	5	s	s	PROPN
clinmedi-182	185	6	,	,	PUNCT
clinmedi-182	185	7	koh	koh	PROPN
clinmedi-182	185	8	w	w	PROPN
clinmedi-182	185	9	,	,	PUNCT
clinmedi-182	185	10	aggarwal	aggarwal	PROPN
clinmedi-182	185	11	bb	bb	PROPN
clinmedi-182	185	12	.	.	PUNCT
clinmedi-182	185	13	discovery	discovery	PROPN
clinmedi-182	185	14	of	of	ADP
clinmedi-182	185	15	curcumin	curcumin	NOUN
clinmedi-182	185	16	,	,	PUNCT
clinmedi-182	185	17	a	a	DET
clinmedi-182	185	18	component	component	NOUN
clinmedi-182	185	19	of	of	ADP
clinmedi-182	185	20	golden	golden	ADJ
clinmedi-182	185	21	spice	spice	NOUN
clinmedi-182	185	22	,	,	PUNCT
clinmedi-182	185	23	and	and	CCONJ
clinmedi-182	185	24	its	its	PRON
clinmedi-182	185	25	miraculous	miraculous	ADJ
clinmedi-182	185	26	biological	biological	ADJ
clinmedi-182	185	27	activities	activity	NOUN
clinmedi-182	185	28	.	.	PUNCT
clinmedi-182	186	1	clin	clin	PROPN
clinmedi-182	186	2	exp	exp	NOUN
clinmedi-182	186	3	pharmacol	pharmacol	PROPN
clinmedi-182	186	4	physiol	physiol	PROPN
clinmedi-182	186	5	2012;39:283	2012;39:283	PROPN
clinmedi-182	186	6	-	-	SYM
clinmedi-182	186	7	299	299	NUM
clinmedi-182	186	8	6	6	NUM
clinmedi-182	186	9	.	.	PUNCT
clinmedi-182	187	1	menon	menon	PROPN
clinmedi-182	187	2	vp	vp	PROPN
clinmedi-182	187	3	,	,	PUNCT
clinmedi-182	187	4	sudheer	sudheer	PROPN
clinmedi-182	187	5	ar	ar	PROPN
clinmedi-182	187	6	.	.	PROPN
clinmedi-182	187	7	antioxidant	antioxidant	PROPN
clinmedi-182	187	8	and	and	CCONJ
clinmedi-182	187	9	antiinflammatory	antiinflammatory	NOUN
clinmedi-182	187	10	properties	property	NOUN
clinmedi-182	187	11	of	of	ADP
clinmedi-182	187	12	curcumin	curcumin	NOUN
clinmedi-182	187	13	.	.	PUNCT
clinmedi-182	188	1	adv	adv	PROPN
clinmedi-182	188	2	exp	exp	NOUN
clinmedi-182	188	3	med	med	ADJ
clinmedi-182	188	4	biol	biol	NOUN
clinmedi-182	188	5	.	.	PUNCT
clinmedi-182	189	1	2007;595:105	2007;595:105	NUM
clinmedi-182	189	2	-	-	SYM
clinmedi-182	189	3	125	125	NUM
clinmedi-182	189	4	7	7	NUM
clinmedi-182	189	5	.	.	PUNCT
clinmedi-182	189	6	rao	rao	PROPN
clinmedi-182	189	7	cv	cv	PROPN
clinmedi-182	189	8	.	.	PROPN
clinmedi-182	189	9	regulation	regulation	NOUN
clinmedi-182	189	10	of	of	ADP
clinmedi-182	189	11	cox	cox	PROPN
clinmedi-182	189	12	and	and	CCONJ
clinmedi-182	189	13	lox	lox	PROPN
clinmedi-182	189	14	by	by	ADP
clinmedi-182	189	15	curcumin	curcumin	PROPN
clinmedi-182	189	16	.	.	PUNCT
clinmedi-182	190	1	adv	adv	PROPN
clinmedi-182	190	2	exp	exp	NOUN
clinmedi-182	190	3	med	med	ADJ
clinmedi-182	190	4	biol	biol	NOUN
clinmedi-182	190	5	.	.	PUNCT
clinmedi-182	191	1	2007;595:213226	2007;595:213226	NUM
clinmedi-182	191	2	8	8	X
clinmedi-182	191	3	.	.	X
clinmedi-182	191	4	milacic	milacic	NOUN
clinmedi-182	191	5	v	v	PROPN
clinmedi-182	191	6	,	,	PUNCT
clinmedi-182	191	7	banerjee	banerjee	PROPN
clinmedi-182	191	8	s	s	PROPN
clinmedi-182	191	9	,	,	PUNCT
clinmedi-182	191	10	landis	landis	NOUN
clinmedi-182	191	11	-	-	PUNCT
clinmedi-182	191	12	piwowar	piwowar	NOUN
clinmedi-182	191	13	kr	kr	PROPN
clinmedi-182	191	14	,	,	PUNCT
clinmedi-182	191	15	sarkar	sarkar	PROPN
clinmedi-182	191	16	fh	fh	PROPN
clinmedi-182	191	17	,	,	PUNCT
clinmedi-182	191	18	majumbar	majumbar	PROPN
clinmedi-182	191	19	ap	ap	PROPN
clinmedi-182	191	20	,	,	PUNCT
clinmedi-182	191	21	dou	dou	PROPN
clinmedi-182	191	22	qp	qp	PROPN
clinmedi-182	191	23	.	.	PROPN
clinmedi-182	191	24	curcumin	curcumin	PROPN
clinmedi-182	191	25	inhibits	inhibit	VERB
clinmedi-182	191	26	the	the	DET
clinmedi-182	191	27	proteasome	proteasome	NOUN
clinmedi-182	191	28	activity	activity	NOUN
clinmedi-182	191	29	in	in	ADP
clinmedi-182	191	30	human	human	ADJ
clinmedi-182	191	31	colon	colon	NOUN
clinmedi-182	191	32	cancer	cancer	NOUN
clinmedi-182	191	33	cells	cell	NOUN
clinmedi-182	191	34	in	in	ADP
clinmedi-182	191	35	vitro	vitro	X
clinmedi-182	191	36	and	and	CCONJ
clinmedi-182	191	37	in	in	ADP
clinmedi-182	191	38	vivo	vivo	NOUN
clinmedi-182	191	39	.	.	PUNCT
clinmedi-182	192	1	cancer	cancer	NOUN
clinmedi-182	192	2	res	re	NOUN
clinmedi-182	192	3	2008;68:7283	2008;68:7283	NUM
clinmedi-182	192	4	-	-	SYM
clinmedi-182	192	5	7292	7292	NUM
clinmedi-182	192	6	9	9	NUM
clinmedi-182	192	7	.	.	PUNCT
clinmedi-182	193	1	buhrmann	buhrmann	PROPN
clinmedi-182	193	2	c	c	X
clinmedi-182	193	3	,	,	PUNCT
clinmedi-182	193	4	mobasheri	mobasheri	X
clinmedi-182	193	5	a	a	X
clinmedi-182	193	6	,	,	PUNCT
clinmedi-182	193	7	matis	matis	PROPN
clinmedi-182	193	8	u	u	PROPN
clinmedi-182	193	9	,	,	PUNCT
clinmedi-182	193	10	shakibaei	shakibaei	PROPN
clinmedi-182	193	11	m.	m.	PROPN
clinmedi-182	193	12	curcumin	curcumin	PROPN
clinmedi-182	193	13	mediated	mediate	VERB
clinmedi-182	193	14	suppression	suppression	NOUN
clinmedi-182	193	15	of	of	ADP
clinmedi-182	193	16	nuclear	nuclear	ADJ
clinmedi-182	193	17	factor	factor	NOUN
clinmedi-182	193	18	-	-	PUNCT
clinmedi-182	193	19	kb	kb	PROPN
clinmedi-182	193	20	promotes	promote	VERB
clinmedi-182	193	21	chondrogenic	chondrogenic	ADJ
clinmedi-182	193	22	differentiation	differentiation	NOUN
clinmedi-182	193	23	of	of	ADP
clinmedi-182	193	24	mesenchymal	mesenchymal	ADJ
clinmedi-182	193	25	stem	stem	NOUN
clinmedi-182	193	26	cells	cell	NOUN
clinmedi-182	193	27	in	in	ADP
clinmedi-182	193	28	a	a	DET
clinmedi-182	193	29	high	high	ADJ
clinmedi-182	193	30	-	-	PUNCT
clinmedi-182	193	31	density	density	NOUN
clinmedi-182	193	32	co	co	NOUN
clinmedi-182	193	33	-	-	NOUN
clinmedi-182	193	34	culture	culture	ADJ
clinmedi-182	193	35	microenvironment	microenvironment	NOUN
clinmedi-182	193	36	.	.	PUNCT
clinmedi-182	194	1	arthritis	arthritis	NOUN
clinmedi-182	194	2	res	re	NOUN
clinmedi-182	194	3	ther	ther	ADV
clinmedi-182	194	4	2010;12	2010;12	NOUN
clinmedi-182	194	5	:	:	PUNCT
clinmedi-182	195	1	r127	r127	NOUN
clinmedi-182	195	2	10	10	NUM
clinmedi-182	195	3	.	.	PUNCT
clinmedi-182	196	1	mathy	mathy	ADJ
clinmedi-182	196	2	-	-	PUNCT
clinmedi-182	196	3	hartert	hartert	PROPN
clinmedi-182	196	4	m	m	PROPN
clinmedi-182	196	5	,	,	PUNCT
clinmedi-182	196	6	jacquemond	jacquemond	NOUN
clinmedi-182	196	7	-	-	PUNCT
clinmedi-182	196	8	collet	collet	NOUN
clinmedi-182	196	9	i	i	NOUN
clinmedi-182	196	10	,	,	PUNCT
clinmedi-182	196	11	priem	priem	PROPN
clinmedi-182	196	12	f	f	PROPN
clinmedi-182	196	13	,	,	PUNCT
clinmedi-182	196	14	sanchez	sanchez	PROPN
clinmedi-182	196	15	c	c	AUX
clinmedi-182	196	16	,	,	PUNCT
clinmedi-182	196	17	lambert	lambert	PROPN
clinmedi-182	196	18	c	c	PROPN
clinmedi-182	196	19	,	,	PUNCT
clinmedi-182	196	20	henrotin	henrotin	PROPN
clinmedi-182	196	21	y.	y.	PROPN
clinmedi-182	196	22	curcumin	curcumin	PROPN
clinmedi-182	196	23	inhibits	inhibit	VERB
clinmedi-182	196	24	pro	pro	ADJ
clinmedi-182	196	25	-	-	ADJ
clinmedi-182	196	26	inflammatory	inflammatory	ADJ
clinmedi-182	196	27	mediators	mediator	NOUN
clinmedi-182	196	28	and	and	CCONJ
clinmedi-182	196	29	metalloproteinase-3	metalloproteinase-3	NUM
clinmedi-182	196	30	production	production	NOUN
clinmedi-182	196	31	by	by	ADP
clinmedi-182	196	32	chondrocytes	chondrocyte	NOUN
clinmedi-182	196	33	.	.	PUNCT
clinmedi-182	197	1	inflamm	inflamm	PROPN
clinmedi-182	197	2	res	re	VERB
clinmedi-182	197	3	2009;58:899	2009;58:899	PROPN
clinmedi-182	197	4	-	-	NUM
clinmedi-182	197	5	908	908	NUM
clinmedi-182	197	6	11	11	NUM
clinmedi-182	197	7	.	.	PUNCT
clinmedi-182	198	1	wongcharoen	wongcharoen	PROPN
clinmedi-182	198	2	w	w	PROPN
clinmedi-182	198	3	,	,	PUNCT
clinmedi-182	198	4	phrommintikul	phrommintikul	NOUN
clinmedi-182	198	5	a.	a.	NOUN
clinmedi-182	198	6	the	the	DET
clinmedi-182	198	7	protective	protective	ADJ
clinmedi-182	198	8	role	role	NOUN
clinmedi-182	198	9	of	of	ADP
clinmedi-182	198	10	curcumin	curcumin	NOUN
clinmedi-182	198	11	in	in	ADP
clinmedi-182	198	12	cardiovascular	cardiovascular	ADJ
clinmedi-182	198	13	diseases	disease	NOUN
clinmedi-182	198	14	.	.	PUNCT
clinmedi-182	199	1	int	int	NOUN
clinmedi-182	199	2	j	j	PROPN
clinmedi-182	199	3	cardio	cardio	NOUN
clinmedi-182	199	4	2009;133:145	2009;133:145	NUM
clinmedi-182	199	5	-	-	SYM
clinmedi-182	199	6	151	151	NUM
clinmedi-182	199	7	12	12	NUM
clinmedi-182	199	8	.	.	PUNCT
clinmedi-182	200	1	sasaki	sasaki	PROPN
clinmedi-182	200	2	h	h	PROPN
clinmedi-182	200	3	,	,	PUNCT
clinmedi-182	200	4	sunagawa	sunagawa	PROPN
clinmedi-182	200	5	y	y	PROPN
clinmedi-182	200	6	,	,	PUNCT
clinmedi-182	200	7	takahashi	takahashi	PROPN
clinmedi-182	200	8	k	k	PROPN
clinmedi-182	200	9	,	,	PUNCT
clinmedi-182	200	10	imaizumi	imaizumi	PROPN
clinmedi-182	200	11	a	a	PROPN
clinmedi-182	200	12	,	,	PUNCT
clinmedi-182	200	13	fukuda	fukuda	NOUN
clinmedi-182	200	14	h	h	PROPN
clinmedi-182	200	15	,	,	PUNCT
clinmedi-182	200	16	hashimoto	hashimoto	NOUN
clinmedi-182	200	17	t	t	PROPN
clinmedi-182	200	18	et	et	PROPN
clinmedi-182	200	19	al	al	PROPN
clinmedi-182	200	20	.	.	PROPN
clinmedi-182	201	1	innovative	innovative	ADJ
clinmedi-182	201	2	preparation	preparation	NOUN
clinmedi-182	201	3	of	of	ADP
clinmedi-182	201	4	curcumin	curcumin	NOUN
clinmedi-182	201	5	for	for	ADP
clinmedi-182	201	6	improved	improved	ADJ
clinmedi-182	201	7	oral	oral	ADJ
clinmedi-182	201	8	bioavailability	bioavailability	NOUN
clinmedi-182	201	9	.	.	PUNCT
clinmedi-182	202	1	biological	biological	PROPN
clinmedi-182	202	2	&	&	CCONJ
clinmedi-182	202	3	pharmaceutical	pharmaceutical	PROPN
clinmedi-182	202	4	bulletin	bulletin	NOUN
clinmedi-182	202	5	,	,	PUNCT
clinmedi-182	202	6	2011	2011	NUM
clinmedi-182	202	7	;	;	PUNCT
clinmedi-182	202	8	34	34	NUM
clinmedi-182	202	9	:	:	PUNCT
clinmedi-182	202	10	660	660	NUM
clinmedi-182	202	11	-	-	SYM
clinmedi-182	202	12	665	665	NUM
clinmedi-182	202	13	13	13	NUM
clinmedi-182	202	14	.	.	PUNCT
clinmedi-182	203	1	sunagawa	sunagawa	PROPN
clinmedi-182	203	2	y	y	PROPN
clinmedi-182	203	3	,	,	PUNCT
clinmedi-182	203	4	hirano	hirano	PROPN
clinmedi-182	203	5	s	s	PROPN
clinmedi-182	203	6	,	,	PUNCT
clinmedi-182	203	7	katanakase	katanakase	PROPN
clinmedi-182	203	8	y	y	PROPN
clinmedi-182	203	9	,	,	PUNCT
clinmedi-182	203	10	miyazaki	miyazaki	PROPN
clinmedi-182	203	11	y	y	PROPN
clinmedi-182	203	12	,	,	PUNCT
clinmedi-182	203	13	funamoto	funamoto	ADJ
clinmedi-182	203	14	m	m	PROPN
clinmedi-182	203	15	,	,	PUNCT
clinmedi-182	203	16	okamura	okamura	PRON
clinmedi-182	203	17	n	n	PROPN
clinmedi-182	203	18	et	et	PROPN
clinmedi-182	203	19	al	al	PROPN
clinmedi-182	203	20	.	.	PROPN
clinmedi-182	203	21	colloidal	colloidal	PROPN
clinmedi-182	203	22	submicron	submicron	NOUN
clinmedi-182	203	23	-	-	PUNCT
clinmedi-182	203	24	particle	particle	NOUN
clinmedi-182	203	25	curcumin	curcumin	NOUN
clinmedi-182	203	26	exhibits	exhibit	VERB
clinmedi-182	203	27	high	high	ADJ
clinmedi-182	203	28	absorption	absorption	NOUN
clinmedi-182	203	29	efficiency	efficiency	NOUN
clinmedi-182	203	30	-	-	PUNCT
clinmedi-182	203	31	a	a	DET
clinmedi-182	203	32	double	double	ADJ
clinmedi-182	203	33	-	-	PUNCT
clinmedi-182	203	34	blinded	blind	VERB
clinmedi-182	203	35	,	,	PUNCT
clinmedi-182	203	36	3way	3way	NOUN
clinmedi-182	203	37	crossover	crossover	NOUN
clinmedi-182	203	38	study	study	NOUN
clinmedi-182	203	39	.	.	PUNCT
clinmedi-182	204	1	j	j	PROPN
clinmedi-182	204	2	nutritional	nutritional	ADJ
clinmedi-182	204	3	science	science	NOUN
clinmedi-182	204	4	and	and	CCONJ
clinmedi-182	204	5	vitaminology	vitaminology	NOUN
clinmedi-182	204	6	2015	2015	NUM
clinmedi-182	204	7	;	;	PUNCT
clinmedi-182	204	8	61	61	NUM
clinmedi-182	204	9	:	:	SYM
clinmedi-182	204	10	37	37	NUM
clinmedi-182	204	11	-	-	SYM
clinmedi-182	204	12	44	44	NUM
clinmedi-182	204	13	14	14	NUM
clinmedi-182	204	14	.	.	PUNCT
clinmedi-182	205	1	nakagawa	nakagawa	PROPN
clinmedi-182	205	2	y	y	PROPN
clinmedi-182	205	3	,	,	PUNCT
clinmedi-182	205	4	mukai	mukai	PROPN
clinmedi-182	205	5	s	s	PROPN
clinmedi-182	205	6	,	,	PUNCT
clinmedi-182	205	7	yamada	yamada	PROPN
clinmedi-182	205	8	s	s	PROPN
clinmedi-182	205	9	,	,	PUNCT
clinmedi-182	205	10	matsuoka	matsuoka	VERB
clinmedi-182	205	11	m	m	PROPN
clinmedi-182	205	12	,	,	PUNCT
clinmedi-182	205	13	tarumi	tarumi	PROPN
clinmedi-182	205	14	e	e	PROPN
clinmedi-182	205	15	,	,	PUNCT
clinmedi-182	205	16	hashimoto	hashimoto	NOUN
clinmedi-182	205	17	t	t	PROPN
clinmedi-182	205	18	et	et	PROPN
clinmedi-182	205	19	al	al	PROPN
clinmedi-182	205	20	.	.	PUNCT
clinmedi-182	206	1	short	short	ADJ
clinmedi-182	206	2	-	-	PUNCT
clinmedi-182	206	3	term	term	NOUN
clinmedi-182	206	4	effects	effect	NOUN
clinmedi-182	206	5	of	of	ADP
clinmedi-182	206	6	highly	highly	ADV
clinmedi-182	206	7	-	-	PUNCT
clinmedi-182	206	8	bioavailable	bioavailable	ADJ
clinmedi-182	206	9	curcumin	curcumin	NOUN
clinmedi-182	206	10	for	for	ADP
clinmedi-182	206	11	treating	treat	VERB
clinmedi-182	206	12	knee	knee	NOUN
clinmedi-182	206	13	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	206	14	:	:	PUNCT
clinmedi-182	206	15	a	a	DET
clinmedi-182	206	16	randomized	randomized	ADJ
clinmedi-182	206	17	,	,	PUNCT
clinmedi-182	206	18	double	double	ADJ
clinmedi-182	206	19	-	-	PUNCT
clinmedi-182	206	20	blind	blind	ADJ
clinmedi-182	206	21	,	,	PUNCT
clinmedi-182	206	22	placebo	placebo	NOUN
clinmedi-182	206	23	-	-	PUNCT
clinmedi-182	206	24	controlled	control	VERB
clinmedi-182	206	25	prospective	prospective	ADJ
clinmedi-182	206	26	study	study	NOUN
clinmedi-182	206	27	.	.	PUNCT
clinmedi-182	207	1	j	j	PROPN
clinmedi-182	207	2	orthop	orthop	PROPN
clinmedi-182	207	3	sci	sci	PROPN
clinmedi-182	207	4	2014	2014	NUM
clinmedi-182	207	5	,	,	PUNCT
clinmedi-182	207	6	19	19	NUM
clinmedi-182	207	7	:	:	SYM
clinmedi-182	207	8	933	933	NUM
clinmedi-182	207	9	-	-	SYM
clinmedi-182	207	10	939	939	NUM
clinmedi-182	207	11	15	15	NUM
clinmedi-182	207	12	.	.	PUNCT
clinmedi-182	208	1	sunagawa	sunagawa	PROPN
clinmedi-182	208	2	y	y	PROPN
clinmedi-182	208	3	,	,	PUNCT
clinmedi-182	208	4	miyazaki	miyazaki	PROPN
clinmedi-182	208	5	y	y	PROPN
clinmedi-182	208	6	,	,	PUNCT
clinmedi-182	208	7	funamoto	funamoto	PROPN
clinmedi-182	208	8	m	m	PROPN
clinmedi-182	208	9	,	,	PUNCT
clinmedi-182	208	10	cmi	cmi	PROPN
clinmedi-182	208	11	04	04	NUM
clinmedi-182	208	12	(	(	PUNCT
clinmedi-182	208	13	03	03	NUM
clinmedi-182	208	14	)	)	PUNCT
clinmedi-182	208	15	,	,	PUNCT
clinmedi-182	208	16	415−429	415−429	PROPN
clinmedi-182	208	17	cmi	cmi	PROPN
clinmedi-182	208	18	journal	journal	PROPN
clinmedi-182	208	19	428	428	NUM
clinmedi-182	208	20	cmi	cmi	PROPN
clinmedi-182	208	21	journal	journal	PROPN
clinmedi-182	208	22	yasuaki	yasuaki	PROPN
clinmedi-182	208	23	nakagawa	nakagawa	PROPN
clinmedi-182	208	24	,	,	PUNCT
clinmedi-182	208	25	md	md	PROPN
clinmedi-182	208	26	shimizu	shimizu	PROPN
clinmedi-182	208	27	k	k	PROPN
clinmedi-182	208	28	,	,	PUNCT
clinmedi-182	208	29	shimizu	shimizu	PROPN
clinmedi-182	208	30	s	s	PROPN
clinmedi-182	208	31	,	,	PUNCT
clinmedi-182	208	32	nurmila	nurmila	PROPN
clinmedi-182	208	33	s	s	PROPN
clinmedi-182	208	34	et	et	NOUN
clinmedi-182	208	35	al	al	PROPN
clinmedi-182	208	36	.	.	PUNCT
clinmedi-182	209	1	a	a	DET
clinmedi-182	209	2	novel	novel	ADJ
clinmedi-182	209	3	amorphous	amorphous	ADJ
clinmedi-182	209	4	preparation	preparation	NOUN
clinmedi-182	209	5	improved	improve	VERB
clinmedi-182	209	6	curcumin	curcumin	NOUN
clinmedi-182	209	7	bioavailability	bioavailability	NOUN
clinmedi-182	209	8	in	in	ADP
clinmedi-182	209	9	healthy	healthy	ADJ
clinmedi-182	209	10	volunteers	volunteer	NOUN
clinmedi-182	209	11	:	:	PUNCT
clinmedi-182	209	12	a	a	DET
clinmedi-182	209	13	singledose	singledose	NOUN
clinmedi-182	209	14	,	,	PUNCT
clinmedi-182	209	15	double	double	ADJ
clinmedi-182	209	16	-	-	PUNCT
clinmedi-182	209	17	blind	blind	ADJ
clinmedi-182	209	18	,	,	PUNCT
clinmedi-182	209	19	two	two	NUM
clinmedi-182	209	20	-	-	PUNCT
clinmedi-182	209	21	way	way	NOUN
clinmedi-182	209	22	crossover	crossover	NOUN
clinmedi-182	209	23	study	study	NOUN
clinmedi-182	209	24	.	.	PUNCT
clinmedi-182	210	1	j	j	PROPN
clinmedi-182	210	2	functional	functional	ADJ
clinmedi-182	210	3	foods	food	NOUN
clinmedi-182	210	4	2021	2021	NUM
clinmedi-182	210	5	;	;	PUNCT
clinmedi-182	210	6	81	81	NUM
clinmedi-182	210	7	https://doi.org/10	https://doi.org/10	NOUN
clinmedi-182	210	8	.	.	PUNCT
clinmedi-182	211	1	1016	1016	NUM
clinmedi-182	211	2	/	/	SYM
clinmedi-182	211	3	j.jff.2021.104443	j.jff.2021.104443	PROPN
clinmedi-182	211	4	16	16	NUM
clinmedi-182	211	5	.	.	PUNCT
clinmedi-182	212	1	akai	akai	PROPN
clinmedi-182	212	2	m	m	PROPN
clinmedi-182	212	3	,	,	PUNCT
clinmedi-182	212	4	doi	doi	PROPN
clinmedi-182	212	5	t	t	PROPN
clinmedi-182	212	6	,	,	PUNCT
clinmedi-182	212	7	fujino	fujino	PROPN
clinmedi-182	212	8	k	k	PROPN
clinmedi-182	212	9	,	,	PUNCT
clinmedi-182	212	10	iwaya	iwaya	PROPN
clinmedi-182	212	11	t	t	PROPN
clinmedi-182	212	12	,	,	PUNCT
clinmedi-182	212	13	kurosawa	kurosawa	PROPN
clinmedi-182	212	14	h	h	PROPN
clinmedi-182	212	15	,	,	PUNCT
clinmedi-182	212	16	nasu	nasu	PROPN
clinmedi-182	212	17	t.	t.	PROPN
clinmedi-182	212	18	an	an	DET
clinmedi-182	212	19	outcome	outcome	NOUN
clinmedi-182	212	20	measure	measure	NOUN
clinmedi-182	212	21	for	for	ADP
clinmedi-182	212	22	japanese	japanese	ADJ
clinmedi-182	212	23	people	people	NOUN
clinmedi-182	212	24	with	with	ADP
clinmedi-182	212	25	knee	knee	NOUN
clinmedi-182	212	26	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	212	27	.	.	PUNCT
clinmedi-182	213	1	j	j	PROPN
clinmedi-182	213	2	rheum	rheum	PROPN
clinmedi-182	213	3	2005	2005	NUM
clinmedi-182	213	4	;	;	PUNCT
clinmedi-182	213	5	32:1524	32:1524	NUM
clinmedi-182	213	6	-	-	SYM
clinmedi-182	213	7	1532	1532	NUM
clinmedi-182	213	8	17	17	NUM
clinmedi-182	213	9	.	.	PUNCT
clinmedi-182	214	1	matsuno	matsuno	PROPN
clinmedi-182	214	2	h	h	PROPN
clinmedi-182	214	3	,	,	PUNCT
clinmedi-182	214	4	kadowaki	kadowaki	PROPN
clinmedi-182	214	5	km	km	PROPN
clinmedi-182	214	6	,	,	PUNCT
clinmedi-182	214	7	tsuji	tsuji	PROPN
clinmedi-182	214	8	h.	h.	PROPN
clinmedi-182	214	9	generation	generation	PROPN
clinmedi-182	214	10	ii	ii	PROPN
clinmedi-182	214	11	knee	knee	NOUN
clinmedi-182	214	12	bracing	brace	VERB
clinmedi-182	214	13	for	for	ADP
clinmedi-182	214	14	severe	severe	ADJ
clinmedi-182	214	15	medial	medial	ADJ
clinmedi-182	214	16	compartment	compartment	NOUN
clinmedi-182	214	17	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	214	18	of	of	ADP
clinmedi-182	214	19	the	the	DET
clinmedi-182	214	20	knee	knee	NOUN
clinmedi-182	214	21	.	.	PUNCT
clinmedi-182	215	1	arch	arch	ADJ
clinmedi-182	215	2	phys	phy	NOUN
clinmedi-182	215	3	med	me	VERB
clinmedi-182	215	4	rehabil	rehabil	ADJ
clinmedi-182	215	5	1997;78:745	1997;78:745	NUM
clinmedi-182	215	6	-	-	SYM
clinmedi-182	215	7	749	749	NUM
clinmedi-182	215	8	18	18	NUM
clinmedi-182	215	9	.	.	PUNCT
clinmedi-182	216	1	dobson	dobson	PROPN
clinmedi-182	216	2	f	f	PROPN
clinmedi-182	216	3	,	,	PUNCT
clinmedi-182	216	4	hinman	hinman	NOUN
clinmedi-182	216	5	rs	rs	NOUN
clinmedi-182	216	6	,	,	PUNCT
clinmedi-182	216	7	hall	hall	PROPN
clinmedi-182	216	8	m	m	PROPN
clinmedi-182	216	9	,	,	PUNCT
clinmedi-182	216	10	terwee	terwee	PROPN
clinmedi-182	216	11	cb	cb	PROPN
clinmedi-182	216	12	,	,	PUNCT
clinmedi-182	216	13	roos	roo	VERB
clinmedi-182	216	14	em	em	PRON
clinmedi-182	216	15	,	,	PUNCT
clinmedi-182	216	16	bennell	bennell	PROPN
clinmedi-182	216	17	kl	kl	PROPN
clinmedi-182	216	18	.	.	PROPN
clinmedi-182	216	19	measurement	measurement	NOUN
clinmedi-182	216	20	properties	property	NOUN
clinmedi-182	216	21	of	of	ADP
clinmedi-182	216	22	performance	performance	NOUN
clinmedi-182	216	23	-	-	PUNCT
clinmedi-182	216	24	based	base	VERB
clinmedi-182	216	25	measures	measure	NOUN
clinmedi-182	216	26	to	to	PART
clinmedi-182	216	27	assess	assess	VERB
clinmedi-182	216	28	physical	physical	ADJ
clinmedi-182	216	29	function	function	NOUN
clinmedi-182	216	30	in	in	ADP
clinmedi-182	216	31	hip	hip	NOUN
clinmedi-182	216	32	and	and	CCONJ
clinmedi-182	216	33	knee	knee	NOUN
clinmedi-182	216	34	oateoarthritis	oateoarthritis	PROPN
clinmedi-182	216	35	.	.	PUNCT
clinmedi-182	217	1	a	a	DET
clinmedi-182	217	2	systematic	systematic	ADJ
clinmedi-182	217	3	review	review	NOUN
clinmedi-182	217	4	.	.	PUNCT
clinmedi-182	218	1	osteoarthr	osteoarthr	PROPN
clinmedi-182	218	2	cartil	cartil	ADP
clinmedi-182	218	3	2012	2012	NUM
clinmedi-182	218	4	;	;	PUNCT
clinmedi-182	218	5	20:1548	20:1548	X
clinmedi-182	218	6	-	-	SYM
clinmedi-182	218	7	1562	1562	NUM
clinmedi-182	218	8	19	19	NUM
clinmedi-182	218	9	.	.	PUNCT
clinmedi-182	219	1	dobson	dobson	PROPN
clinmedi-182	219	2	f	f	PROPN
clinmedi-182	219	3	,	,	PUNCT
clinmedi-182	219	4	hinman	hinman	NOUN
clinmedi-182	219	5	rs	rs	PROPN
clinmedi-182	219	6	,	,	PUNCT
clinmedi-182	219	7	roos	roo	VERB
clinmedi-182	219	8	em	em	PRON
clinmedi-182	219	9	,	,	PUNCT
clinmedi-182	219	10	abbott	abbott	PROPN
clinmedi-182	219	11	jh	jh	PROPN
clinmedi-182	219	12	,	,	PUNCT
clinmedi-182	219	13	stratford	stratford	PROPN
clinmedi-182	219	14	p	p	PROPN
clinmedi-182	219	15	,	,	PUNCT
clinmedi-182	219	16	davis	davis	PROPN
clinmedi-182	219	17	am	be	AUX
clinmedi-182	219	18	et	et	PROPN
clinmedi-182	219	19	al	al	PROPN
clinmedi-182	219	20	.	.	PROPN
clinmedi-182	219	21	oarsi	oarsi	PROPN
clinmedi-182	219	22	recommended	recommend	VERB
clinmedi-182	219	23	performance	performance	NOUN
clinmedi-182	219	24	-	-	PUNCT
clinmedi-182	219	25	based	base	VERB
clinmedi-182	219	26	tests	test	NOUN
clinmedi-182	219	27	to	to	PART
clinmedi-182	219	28	assess	assess	VERB
clinmedi-182	219	29	physical	physical	ADJ
clinmedi-182	219	30	function	function	NOUN
clinmedi-182	219	31	in	in	ADP
clinmedi-182	219	32	people	people	NOUN
clinmedi-182	219	33	diagnosed	diagnose	VERB
clinmedi-182	219	34	with	with	ADP
clinmedi-182	219	35	hip	hip	NOUN
clinmedi-182	219	36	or	or	CCONJ
clinmedi-182	219	37	knee	knee	NOUN
clinmedi-182	219	38	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	219	39	.	.	PUNCT
clinmedi-182	220	1	osteoarthr	osteoarthr	PROPN
clinmedi-182	220	2	cartil	cartil	ADP
clinmedi-182	220	3	2013	2013	NUM
clinmedi-182	220	4	;	;	PUNCT
clinmedi-182	220	5	21:1042	21:1042	NUM
clinmedi-182	220	6	-	-	SYM
clinmedi-182	220	7	1052	1052	NUM
clinmedi-182	220	8	20	20	NUM
clinmedi-182	220	9	.	.	PUNCT
clinmedi-182	221	1	lopresti	lopresti	PROPN
clinmedi-182	221	2	al	al	PROPN
clinmedi-182	221	3	,	,	PUNCT
clinmedi-182	221	4	smith	smith	PROPN
clinmedi-182	221	5	sj	sj	PROPN
clinmedi-182	221	6	,	,	PUNCT
clinmedi-182	221	7	jackson	jackson	PROPN
clinmedi-182	221	8	-	-	PUNCT
clinmedi-182	221	9	michel	michel	PROPN
clinmedi-182	221	10	s	s	PROPN
clinmedi-182	221	11	,	,	PUNCT
clinmedi-182	221	12	fairchild	fairchild	PROPN
clinmedi-182	221	13	t.	t.	PROPN
clinmedi-182	221	14	an	an	DET
clinmedi-182	221	15	investigation	investigation	NOUN
clinmedi-182	221	16	into	into	ADP
clinmedi-182	221	17	the	the	DET
clinmedi-182	221	18	effects	effect	NOUN
clinmedi-182	221	19	of	of	ADP
clinmedi-182	221	20	a	a	DET
clinmedi-182	221	21	curcumin	curcumin	NOUN
clinmedi-182	221	22	extract	extract	NOUN
clinmedi-182	221	23	(	(	PUNCT
clinmedi-182	221	24	curcugen	curcugen	NOUN
clinmedi-182	221	25	○	○	PROPN
clinmedi-182	221	26	r	r	NOUN
clinmedi-182	221	27	)	)	PUNCT
clinmedi-182	221	28	on	on	ADP
clinmedi-182	221	29	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	221	30	pain	pain	NOUN
clinmedi-182	221	31	of	of	ADP
clinmedi-182	221	32	the	the	DET
clinmedi-182	221	33	knee	knee	NOUN
clinmedi-182	221	34	:	:	PUNCT
clinmedi-182	221	35	a	a	DET
clinmedi-182	221	36	randomized	randomized	ADJ
clinmedi-182	221	37	,	,	PUNCT
clinmedi-182	221	38	doubleblinded	doubleblinde	VERB
clinmedi-182	221	39	,	,	PUNCT
clinmedi-182	221	40	placebo	placebo	NOUN
clinmedi-182	221	41	-	-	PUNCT
clinmedi-182	221	42	controlled	control	VERB
clinmedi-182	221	43	study	study	NOUN
clinmedi-182	221	44	.	.	PUNCT
clinmedi-182	222	1	nutrients	nutrient	NOUN
clinmedi-182	222	2	2022	2022	NUM
clinmedi-182	222	3	;	;	PUNCT
clinmedi-182	222	4	14	14	NUM
clinmedi-182	222	5	:	:	SYM
clinmedi-182	222	6	41	41	NUM
clinmedi-182	222	7	doi.org/10.3390/nu14010041	doi.org/10.3390/nu14010041	NOUN
clinmedi-182	222	8	21	21	NUM
clinmedi-182	222	9	.	.	PUNCT
clinmedi-182	223	1	henrotin	henrotin	PROPN
clinmedi-182	223	2	y	y	PROPN
clinmedi-182	223	3	,	,	PUNCT
clinmedi-182	223	4	priem	priem	PROPN
clinmedi-182	223	5	f	f	NOUN
clinmedi-182	223	6	,	,	PUNCT
clinmedi-182	223	7	mobasheri	mobasheri	PROPN
clinmedi-182	223	8	a.	a.	NOUN
clinmedi-182	223	9	curcumin	curcumin	PROPN
clinmedi-182	223	10	:	:	PUNCT
clinmedi-182	223	11	a	a	DET
clinmedi-182	223	12	new	new	ADJ
clinmedi-182	223	13	paradigm	paradigm	NOUN
clinmedi-182	223	14	and	and	CCONJ
clinmedi-182	223	15	therapeutic	therapeutic	ADJ
clinmedi-182	223	16	opportunity	opportunity	NOUN
clinmedi-182	223	17	for	for	ADP
clinmedi-182	223	18	the	the	DET
clinmedi-182	223	19	treatment	treatment	NOUN
clinmedi-182	223	20	of	of	ADP
clinmedi-182	223	21	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	223	22	:	:	PUNCT
clinmedi-182	223	23	curcumin	curcumin	NOUN
clinmedi-182	223	24	for	for	ADP
clinmedi-182	223	25	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	223	26	management	management	NOUN
clinmedi-182	223	27	.	.	PUNCT
clinmedi-182	224	1	springerplus	springerplus	PROPN
clinmedi-182	224	2	2013	2013	NUM
clinmedi-182	224	3	;	;	PUNCT
clinmedi-182	224	4	2(1	2(1	NUM
clinmedi-182	224	5	):	):	PUNCT
clinmedi-182	224	6	56	56	NUM
clinmedi-182	224	7	.	.	PUNCT
clinmedi-182	225	1	doi:10.1186/2193	doi:10.1186/2193	PROPN
clinmedi-182	225	2	-	-	PUNCT
clinmedi-182	225	3	1801	1801	NUM
clinmedi-182	225	4	-	-	PUNCT
clinmedi-182	225	5	2	2	NUM
clinmedi-182	225	6	-	-	SYM
clinmedi-182	225	7	56	56	NUM
clinmedi-182	225	8	22	22	NUM
clinmedi-182	225	9	.	.	PUNCT
clinmedi-182	226	1	yang	yang	PROPN
clinmedi-182	226	2	ky	ky	PROPN
clinmedi-182	226	3	,	,	PUNCT
clinmedi-182	226	4	lin	lin	PROPN
clinmedi-182	226	5	lc	lc	PROPN
clinmedi-182	226	6	,	,	PUNCT
clinmedi-182	226	7	tseng	tseng	PROPN
clinmedi-182	226	8	ty	ty	PROPN
clinmedi-182	226	9	,	,	PUNCT
clinmedi-182	226	10	wang	wang	PROPN
clinmedi-182	226	11	sc	sc	PROPN
clinmedi-182	226	12	,	,	PUNCT
clinmedi-182	226	13	tsai	tsai	PROPN
clinmedi-182	226	14	th	th	PROPN
clinmedi-182	226	15	.	.	PUNCT
clinmedi-182	226	16	oral	oral	ADJ
clinmedi-182	226	17	bioavailability	bioavailability	NOUN
clinmedi-182	226	18	of	of	ADP
clinmedi-182	226	19	curcumin	curcumin	NOUN
clinmedi-182	226	20	in	in	ADP
clinmedi-182	226	21	rat	rat	NOUN
clinmedi-182	226	22	and	and	CCONJ
clinmedi-182	226	23	the	the	DET
clinmedi-182	226	24	herbal	herbal	ADJ
clinmedi-182	226	25	analysis	analysis	NOUN
clinmedi-182	226	26	from	from	ADP
clinmedi-182	226	27	curcumin	curcumin	NOUN
clinmedi-182	226	28	longa	longa	NOUN
clinmedi-182	226	29	by	by	ADP
clinmedi-182	226	30	lc	lc	PROPN
clinmedi-182	226	31	-	-	PUNCT
clinmedi-182	226	32	ms	ms	PROPN
clinmedi-182	226	33	/	/	SYM
clinmedi-182	226	34	ms	ms	PROPN
clinmedi-182	226	35	.	.	PROPN
clinmedi-182	226	36	j	j	PROPN
clinmedi-182	226	37	chromatogr	chromatogr	PROPN
clinmedi-182	226	38	b	b	PROPN
clinmedi-182	226	39	analyt	analyt	PROPN
clinmedi-182	226	40	technol	technol	PROPN
clinmedi-182	226	41	biomed	biome	VERB
clinmedi-182	226	42	life	life	NOUN
clinmedi-182	226	43	sci	sci	PROPN
clinmedi-182	226	44	.	.	PROPN
clinmedi-182	226	45	2007	2007	NUM
clinmedi-182	226	46	;	;	PUNCT
clinmedi-182	226	47	853(1	853(1	NUM
clinmedi-182	226	48	-	-	SYM
clinmedi-182	226	49	2	2	NUM
clinmedi-182	226	50	):	):	PUNCT
clinmedi-182	226	51	183	183	NUM
clinmedi-182	226	52	-	-	SYM
clinmedi-182	226	53	189	189	NUM
clinmedi-182	226	54	.	.	PUNCT
clinmedi-182	227	1	doi	doi	NOUN
clinmedi-182	227	2	:	:	PUNCT
clinmedi-182	227	3	10.1016	10.1016	NUM
clinmedi-182	227	4	/	/	SYM
clinmedi-182	227	5	j.jchromb.2007.03.010	j.jchromb.2007.03.010	PROPN
clinmedi-182	227	6	23	23	NUM
clinmedi-182	227	7	.	.	PUNCT
clinmedi-182	228	1	zeng	zeng	PROPN
clinmedi-182	228	2	j	j	PROPN
clinmedi-182	228	3	,	,	PUNCT
clinmedi-182	228	4	wang	wang	PROPN
clinmedi-182	228	5	h	h	PROPN
clinmedi-182	228	6	,	,	PUNCT
clinmedi-182	228	7	shen	shen	PROPN
clinmedi-182	229	1	z	z	X
clinmedi-182	229	2	,	,	PUNCT
clinmedi-182	229	3	yao	yao	PROPN
clinmedi-182	229	4	x	x	PRON
clinmedi-182	229	5	,	,	PUNCT
clinmedi-182	229	6	wu	wu	PROPN
clinmedi-182	229	7	c	c	PROPN
clinmedi-182	229	8	,	,	PUNCT
clinmedi-182	229	9	pan	pan	PROPN
clinmedi-182	229	10	t.	t.	PROPN
clinmedi-182	229	11	curcumin	curcumin	PROPN
clinmedi-182	229	12	inhibits	inhibit	VERB
clinmedi-182	229	13	proliferation	proliferation	NOUN
clinmedi-182	229	14	of	of	ADP
clinmedi-182	229	15	synovial	synovial	ADJ
clinmedi-182	229	16	cells	cell	NOUN
clinmedi-182	229	17	by	by	ADP
clinmedi-182	229	18	downregulating	downregulating	NOUN
clinmedi-182	229	19	expression	expression	NOUN
clinmedi-182	229	20	of	of	ADP
clinmedi-182	229	21	matrix	matrix	NOUN
clinmedi-182	229	22	metalloproteinase-3	metalloproteinase-3	VERB
clinmedi-182	229	23	in	in	ADP
clinmedi-182	229	24	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	229	25	.	.	PUNCT
clinmedi-182	230	1	orthopaedic	orthopaedic	ADJ
clinmedi-182	230	2	surgery	surgery	NOUN
clinmedi-182	230	3	2019	2019	NUM
clinmedi-182	230	4	;	;	PUNCT
clinmedi-182	230	5	11	11	NUM
clinmedi-182	230	6	:	:	SYM
clinmedi-182	230	7	117	117	NUM
clinmedi-182	230	8	-	-	SYM
clinmedi-182	230	9	125	125	NUM
clinmedi-182	230	10	24	24	NUM
clinmedi-182	230	11	.	.	PUNCT
clinmedi-182	231	1	nicokuche	nicokuche	PROPN
clinmedi-182	231	2	t	t	PROPN
clinmedi-182	231	3	,	,	PUNCT
clinmedi-182	231	4	maldonado	maldonado	PROPN
clinmedi-182	231	5	dc	dc	PROPN
clinmedi-182	231	6	,	,	PUNCT
clinmedi-182	231	7	faber	faber	PROPN
clinmedi-182	231	8	j	j	PROPN
clinmedi-182	231	9	,	,	PUNCT
clinmedi-182	231	10	sliva	sliva	PROPN
clinmedi-182	231	11	mcp	mcp	PROPN
clinmedi-182	231	12	.	.	PROPN
clinmedi-182	231	13	evaluation	evaluation	NOUN
clinmedi-182	231	14	of	of	ADP
clinmedi-182	231	15	the	the	DET
clinmedi-182	231	16	articular	articular	ADJ
clinmedi-182	231	17	cartilage	cartilage	NOUN
clinmedi-182	231	18	in	in	ADP
clinmedi-182	231	19	the	the	DET
clinmedi-182	231	20	knees	knee	NOUN
clinmedi-182	231	21	of	of	ADP
clinmedi-182	231	22	rats	rat	NOUN
clinmedi-182	231	23	with	with	ADP
clinmedi-182	231	24	induced	induced	ADJ
clinmedi-182	231	25	arthritis	arthritis	NOUN
clinmedi-182	231	26	treated	treat	VERB
clinmedi-182	231	27	with	with	ADP
clinmedi-182	231	28	curcumin	curcumin	NOUN
clinmedi-182	231	29	.	.	PUNCT
clinmedi-182	232	1	plos	plos	PROPN
clinmedi-182	232	2	one	one	NUM
clinmedi-182	232	3	2020	2020	NUM
clinmedi-182	232	4	;	;	PUNCT
clinmedi-182	232	5	15(3	15(3	NUM
clinmedi-182	232	6	):	):	PUNCT
clinmedi-182	232	7	e0230228	e0230228	PROPN
clinmedi-182	232	8	25	25	NUM
clinmedi-182	232	9	.	.	PUNCT
clinmedi-182	233	1	wang	wang	PROPN
clinmedi-182	233	2	j	j	PROPN
clinmedi-182	233	3	,	,	PUNCT
clinmedi-182	233	4	wang	wang	PROPN
clinmedi-182	233	5	x	x	PROPN
clinmedi-182	233	6	,	,	PUNCT
clinmedi-182	233	7	cao	cao	PROPN
clinmedi-182	233	8	y	y	PROPN
clinmedi-182	233	9	,	,	PUNCT
clinmedi-182	233	10	huang	huang	PROPN
clinmedi-182	233	11	t	t	PROPN
clinmedi-182	233	12	,	,	PUNCT
clinmedi-182	233	13	song	song	PROPN
clinmedi-182	233	14	dx	dx	PROPN
clinmedi-182	233	15	,	,	PUNCT
clinmedi-182	233	16	tao	tao	PROPN
clinmedi-182	233	17	hr	hr	PROPN
clinmedi-182	233	18	.	.	PUNCT
clinmedi-182	234	1	therapeutic	therapeutic	ADJ
clinmedi-182	234	2	potential	potential	NOUN
clinmedi-182	234	3	of	of	ADP
clinmedi-182	234	4	hyaluronic	hyaluronic	ADJ
clinmedi-182	234	5	acid	acid	NOUN
clinmedi-182	234	6	/	/	SYM
clinmedi-182	234	7	chitosan	chitosan	NOUN
clinmedi-182	234	8	nanoparticles	nanoparticle	NOUN
clinmedi-182	234	9	for	for	ADP
clinmedi-182	234	10	the	the	DET
clinmedi-182	234	11	delivery	delivery	NOUN
clinmedi-182	234	12	of	of	ADP
clinmedi-182	234	13	curcuminoid	curcuminoid	NOUN
clinmedi-182	234	14	in	in	ADP
clinmedi-182	234	15	knee	knee	NOUN
clinmedi-182	234	16	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	234	17	and	and	CCONJ
clinmedi-182	234	18	an	an	DET
clinmedi-182	234	19	in	in	ADP
clinmedi-182	234	20	vitro	vitro	X
clinmedi-182	234	21	evaluation	evaluation	NOUN
clinmedi-182	234	22	in	in	ADP
clinmedi-182	234	23	chondrocytes	chondrocyte	NOUN
clinmedi-182	234	24	.	.	PUNCT
clinmedi-182	235	1	international	international	ADJ
clinmedi-182	235	2	j	j	PROPN
clinmedi-182	235	3	molecular	molecular	ADJ
clinmedi-182	235	4	med	med	ADJ
clinmedi-182	235	5	2018	2018	NUM
clinmedi-182	235	6	;	;	PUNCT
clinmedi-182	235	7	42	42	NUM
clinmedi-182	235	8	:	:	PUNCT
clinmedi-182	235	9	2604	2604	NUM
clinmedi-182	235	10	-	-	SYM
clinmedi-182	235	11	2614	2614	NUM
clinmedi-182	235	12	26	26	NUM
clinmedi-182	235	13	.	.	PUNCT
clinmedi-182	236	1	wang	wang	PROPN
clinmedi-182	236	2	p	p	PROPN
clinmedi-182	236	3	,	,	PUNCT
clinmedi-182	236	4	ye	ye	PROPN
clinmedi-182	236	5	y	y	PROPN
clinmedi-182	236	6	,	,	PUNCT
clinmedi-182	236	7	yuan	yuan	PROPN
clinmedi-182	236	8	w	w	PROPN
clinmedi-182	236	9	,	,	PUNCT
clinmedi-182	236	10	tan	tan	PROPN
clinmedi-182	236	11	y	y	PROPN
clinmedi-182	236	12	,	,	PUNCT
clinmedi-182	236	13	zhang	zhang	PROPN
clinmedi-182	236	14	s	s	PROPN
clinmedi-182	236	15	,	,	PUNCT
clinmedi-182	236	16	meng	meng	PROPN
clinmedi-182	236	17	q.	q.	PROPN
clinmedi-182	236	18	curcumin	curcumin	PROPN
clinmedi-182	236	19	exerts	exert	VERB
clinmedi-182	236	20	a	a	DET
clinmedi-182	236	21	protective	protective	ADJ
clinmedi-182	236	22	effect	effect	NOUN
clinmedi-182	236	23	on	on	ADP
clinmedi-182	236	24	murine	murine	ADJ
clinmedi-182	236	25	knee	knee	NOUN
clinmedi-182	236	26	chondrocytes	chondrocyte	NOUN
clinmedi-182	236	27	treated	treat	VERB
clinmedi-182	236	28	with	with	ADP
clinmedi-182	236	29	il-1b	il-1b	PROPN
clinmedi-182	236	30	through	through	ADP
clinmedi-182	236	31	blocking	block	VERB
clinmedi-182	236	32	the	the	DET
clinmedi-182	236	33	nf	nf	ADJ
clinmedi-182	236	34	-	-	PUNCT
clinmedi-182	236	35	kb	kb	NOUN
clinmedi-182	236	36	/	/	SYM
clinmedi-182	236	37	hif-2α	hif-2α	NOUN
clinmedi-182	236	38	signaling	signal	VERB
clinmedi-182	236	39	pathway	pathway	NOUN
clinmedi-182	236	40	.	.	PUNCT
clinmedi-182	237	1	ann	ann	PROPN
clinmedi-182	237	2	transl	transl	PROPN
clinmedi-182	237	3	med	med	PROPN
clinmedi-182	237	4	2021;9(11	2021;9(11	NUM
clinmedi-182	237	5	):	):	PUNCT
clinmedi-182	237	6	940	940	NUM
clinmedi-182	237	7	27	27	NUM
clinmedi-182	237	8	.	.	PUNCT
clinmedi-182	238	1	nakahata	nakahata	PROPN
clinmedi-182	238	2	a	a	PROPN
clinmedi-182	238	3	,	,	PUNCT
clinmedi-182	238	4	ito	ito	PROPN
clinmedi-182	238	5	a	a	PRON
clinmedi-182	238	6	,	,	PUNCT
clinmedi-182	238	7	nakahara	nakahara	ADJ
clinmedi-182	238	8	r	r	NOUN
clinmedi-182	238	9	,	,	PUNCT
clinmedi-182	238	10	kishimoto	kishimoto	PROPN
clinmedi-182	238	11	a	a	X
clinmedi-182	238	12	,	,	PUNCT
clinmedi-182	238	13	imaizumi	imaizumi	PROPN
clinmedi-182	238	14	a	a	PRON
clinmedi-182	238	15	,	,	PUNCT
clinmedi-182	238	16	hashimoto	hashimoto	NOUN
clinmedi-182	238	17	t	t	PROPN
clinmedi-182	238	18	et	et	PROPN
clinmedi-182	238	19	al	al	PROPN
clinmedi-182	238	20	.	.	PUNCT
clinmedi-182	239	1	intra	intra	ADJ
clinmedi-182	239	2	-	-	ADJ
clinmedi-182	239	3	articular	articular	ADJ
clinmedi-182	239	4	injections	injection	NOUN
clinmedi-182	239	5	of	of	ADP
clinmedi-182	239	6	curcumin	curcumin	NOUN
clinmedi-182	239	7	monoglucuronide	monoglucuronide	PROPN
clinmedi-182	239	8	tbp1901	tbp1901	PROPN
clinmedi-182	239	9	suppresses	suppress	VERB
clinmedi-182	239	10	articular	articular	ADJ
clinmedi-182	239	11	cartilage	cartilage	NOUN
clinmedi-182	239	12	damage	damage	NOUN
clinmedi-182	239	13	and	and	CCONJ
clinmedi-182	239	14	regulates	regulate	VERB
clinmedi-182	239	15	subchondral	subchondral	ADJ
clinmedi-182	239	16	bone	bone	NOUN
clinmedi-182	239	17	alteration	alteration	NOUN
clinmedi-182	239	18	in	in	ADP
clinmedi-182	239	19	an	an	DET
clinmedi-182	239	20	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	239	21	rat	rat	NOUN
clinmedi-182	239	22	model	model	NOUN
clinmedi-182	239	23	.	.	PUNCT
clinmedi-182	240	1	cartilage	cartilage	NOUN
clinmedi-182	240	2	2021;13	2021;13	NUM
clinmedi-182	240	3	(	(	PUNCT
clinmedi-182	240	4	2_suppl):153s-167s	2_suppl):153s-167s	ADJ
clinmedi-182	240	5	28	28	NUM
clinmedi-182	240	6	.	.	PUNCT
clinmedi-182	241	1	kishimoto	kishimoto	PROPN
clinmedi-182	241	2	a	a	PROPN
clinmedi-182	241	3	,	,	PUNCT
clinmedi-182	241	4	imaizumi	imaizumi	PROPN
clinmedi-182	241	5	a	a	PROPN
clinmedi-182	241	6	,	,	PUNCT
clinmedi-182	241	7	wada	wada	PROPN
clinmedi-182	241	8	h	h	PROPN
clinmedi-182	241	9	,	,	PUNCT
clinmedi-182	241	10	yamakage	yamakage	NOUN
clinmedi-182	241	11	h	h	NOUN
clinmedi-182	241	12	,	,	PUNCT
clinmedi-182	241	13	satoh	satoh	NOUN
clinmedi-182	241	14	-	-	PUNCT
clinmedi-182	241	15	asahara	asahara	NOUN
clinmedi-182	241	16	n	n	CCONJ
clinmedi-182	241	17	,	,	PUNCT
clinmedi-182	241	18	hashimoto	hashimoto	NOUN
clinmedi-182	241	19	t	t	PROPN
clinmedi-182	241	20	et	et	NOUN
clinmedi-182	241	21	al	al	PROPN
clinmedi-182	241	22	.	.	PUNCT
clinmedi-182	242	1	newly	newly	ADV
clinmedi-182	242	2	developed	develop	VERB
clinmedi-182	242	3	highly	highly	ADV
clinmedi-182	242	4	bioavailable	bioavailable	ADJ
clinmedi-182	242	5	formulation	formulation	NOUN
clinmedi-182	242	6	,	,	PUNCT
clinmedi-182	242	7	curcurouge	curcurouge	NOUN
clinmedi-182	242	8	®	®	PROPN
clinmedi-182	242	9	,	,	PUNCT
clinmedi-182	242	10	reduces	reduce	VERB
clinmedi-182	242	11	neutrophil	neutrophil	ADJ
clinmedi-182	242	12	/	/	SYM
clinmedi-182	242	13	lymphocyte	lymphocyte	ADJ
clinmedi-182	242	14	ratio	ratio	NOUN
clinmedi-182	242	15	in	in	ADP
clinmedi-182	242	16	the	the	DET
clinmedi-182	242	17	elderly	elderly	ADJ
clinmedi-182	242	18	:	:	PUNCT
clinmedi-182	242	19	a	a	DET
clinmedi-182	242	20	double	double	ADJ
clinmedi-182	242	21	-	-	PUNCT
clinmedi-182	242	22	blinded	blind	VERB
clinmedi-182	242	23	,	,	PUNCT
clinmedi-182	242	24	placebo	placebo	NOUN
clinmedi-182	242	25	controlled	control	VERB
clinmedi-182	242	26	clinical	clinical	ADJ
clinmedi-182	242	27	trial	trial	NOUN
clinmedi-182	242	28	.	.	PUNCT
clinmedi-182	243	1	j	j	PROPN
clinmedi-182	243	2	nutr	nutr	PROPN
clinmedi-182	243	3	sci	sci	PROPN
clinmedi-182	243	4	vitaminol	vitaminol	NOUN
clinmedi-182	243	5	.	.	PUNCT
clinmedi-182	244	1	2121	2121	NUM
clinmedi-182	244	2	;	;	PUNCT
clinmedi-182	244	3	67	67	NUM
clinmedi-182	244	4	:	:	SYM
clinmedi-182	244	5	249	249	NUM
clinmedi-182	244	6	-	-	SYM
clinmedi-182	244	7	252	252	NUM
clinmedi-182	244	8	29	29	NUM
clinmedi-182	244	9	.	.	PUNCT
clinmedi-182	245	1	bannuru	bannuru	PROPN
clinmedi-182	245	2	rr	rr	PROPN
clinmedi-182	245	3	,	,	PUNCT
clinmedi-182	245	4	osani	osani	PROPN
clinmedi-182	245	5	mc	mc	PROPN
clinmedi-182	245	6	,	,	PUNCT
clinmedi-182	245	7	al	al	PROPN
clinmedi-182	245	8	-	-	PUNCT
clinmedi-182	245	9	eid	eid	PROPN
clinmedi-182	245	10	f	f	PROPN
clinmedi-182	245	11	,	,	PUNCT
clinmedi-182	245	12	wang	wang	PROPN
clinmedi-182	245	13	c.	c.	PROPN
clinmedi-182	245	14	cmi	cmi	PROPN
clinmedi-182	245	15	04	04	PROPN
clinmedi-182	245	16	(	(	PUNCT
clinmedi-182	245	17	03	03	NUM
clinmedi-182	245	18	)	)	PUNCT
clinmedi-182	245	19	,	,	PUNCT
clinmedi-182	245	20	415−429	415−429	PROPN
clinmedi-182	245	21	cmi	cmi	PROPN
clinmedi-182	245	22	journal	journal	PROPN
clinmedi-182	245	23	429	429	NUM
clinmedi-182	245	24	cmi	cmi	PROPN
clinmedi-182	245	25	journal	journal	PROPN
clinmedi-182	245	26	yasuaki	yasuaki	PROPN
clinmedi-182	245	27	nakagawa	nakagawa	PROPN
clinmedi-182	245	28	,	,	PUNCT
clinmedi-182	245	29	md	md	PROPN
clinmedi-182	245	30	efficacy	efficacy	PROPN
clinmedi-182	245	31	of	of	ADP
clinmedi-182	245	32	curcumin	curcumin	NOUN
clinmedi-182	245	33	and	and	CCONJ
clinmedi-182	245	34	boswellia	boswellia	VERB
clinmedi-182	245	35	for	for	ADP
clinmedi-182	245	36	knee	knee	NOUN
clinmedi-182	245	37	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	245	38	:	:	PUNCT
clinmedi-182	245	39	systematic	systematic	ADJ
clinmedi-182	245	40	review	review	NOUN
clinmedi-182	245	41	and	and	CCONJ
clinmedi-182	245	42	metaanalysis	metaanalysis	NOUN
clinmedi-182	245	43	.	.	PUNCT
clinmedi-182	246	1	semin	semin	PROPN
clinmedi-182	246	2	arthritis	arthritis	PROPN
clinmedi-182	246	3	rheum	rheum	PROPN
clinmedi-182	246	4	2018	2018	NUM
clinmedi-182	246	5	;	;	PUNCT
clinmedi-182	246	6	48(3	48(3	NUM
clinmedi-182	246	7	):	):	PUNCT
clinmedi-182	246	8	416	416	NUM
clinmedi-182	246	9	-	-	SYM
clinmedi-182	246	10	429	429	NUM
clinmedi-182	246	11	30	30	NUM
clinmedi-182	246	12	.	.	PUNCT
clinmedi-182	247	1	hsiao	hsiao	PROPN
clinmedi-182	247	2	af	af	PROPN
clinmedi-182	247	3	,	,	PUNCT
clinmedi-182	247	4	lien	lien	PROPN
clinmedi-182	247	5	yc	yc	PROPN
clinmedi-182	247	6	,	,	PUNCT
clinmedi-182	247	7	tzeng	tzeng	PROPN
clinmedi-182	247	8	is	be	AUX
clinmedi-182	247	9	,	,	PUNCT
clinmedi-182	247	10	liu	liu	PROPN
clinmedi-182	247	11	ct	ct	PROPN
clinmedi-182	247	12	,	,	PUNCT
clinmedi-182	247	13	chou	chou	PROPN
clinmedi-182	247	14	sh	sh	PROPN
clinmedi-182	247	15	,	,	PUNCT
clinmedi-182	247	16	horng	horng	PROPN
clinmedi-182	247	17	ys	ys	NOUN
clinmedi-182	247	18	.	.	PUNCT
clinmedi-182	248	1	the	the	DET
clinmedi-182	248	2	efficacy	efficacy	NOUN
clinmedi-182	248	3	of	of	ADP
clinmedi-182	248	4	highand	highand	ADJ
clinmedi-182	248	5	lowdose	lowdose	ADJ
clinmedi-182	248	6	curcumin	curcumin	NOUN
clinmedi-182	248	7	in	in	ADP
clinmedi-182	248	8	knee	knee	NOUN
clinmedi-182	248	9	osteoarthritis	osteoarthritis	NOUN
clinmedi-182	248	10	:	:	PUNCT
clinmedi-182	248	11	a	a	DET
clinmedi-182	248	12	systematic	systematic	ADJ
clinmedi-182	248	13	review	review	NOUN
clinmedi-182	248	14	and	and	CCONJ
clinmedi-182	248	15	meta	meta	ADJ
clinmedi-182	248	16	-	-	PUNCT
clinmedi-182	248	17	analysis	analysis	NOUN
clinmedi-182	248	18	.	.	PUNCT
clinmedi-182	249	1	complementary	complementary	ADJ
clinmedi-182	249	2	therapies	therapy	NOUN
clinmedi-182	249	3	in	in	ADP
clinmedi-182	249	4	medicine	medicine	NOUN
clinmedi-182	249	5	2021	2021	NUM
clinmedi-182	249	6	;	;	PUNCT
clinmedi-182	249	7	63	63	NUM
clinmedi-182	249	8	:	:	SYM
clinmedi-182	249	9	102775	102775	NUM