id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ct-12703	Dockweiler, Jenna ; Rickard, Valeria; Leon-Frank, Daniel; Premanandan, Christopher; Boyko, Adam; Kawakami, Takeshi	Use of a direct-to-consumer genetic screening test for diagnosis of a chromosomal abnormality in a female dog	2025	4	.pdf	application/pdf	2374	110	39	Bennett NE, Johnson EA, Gray PB: Veterinary care providers recog- nize clinical utility of genetic testing but report limited confidence in interpreting direct-to-consumer results. Hormones Patient Spayed female Intact female Neutered male Intact male Estradiol (pg/ml) 32.1 30.8 – 69.9 31.5 – 65.4 23.1 – 65.1 30.5 – 66.6 Progesterone (ng/ml) < 0.20 < 0.20 – 0.49 < 0.20 – 2.16 < 0.20 < 0.20 – 0.40 Testosterone (ng/ml) < 15.0 < 15.0 – 32.0 < 15.0 < 15.0 – 24.0 19.0 – 2630.0 http://dx.doi.org/10.58292/CT.v17.12703 Citation: Clinical Theriogenology 2025, 17, 12703, http://dx.doi.org/10.58292/CT.v17.12703 3 Cytogenetic analysis in the dog is challenging due to a high diploid chromosome number (78 autosomes and a pair of sex chromosomes) and the one-arm morphology of the autosomes.1 Microarrays can assess chromosomal imbal- ances and may detect small anomalies beyond the resolu- tion of routine karyotyping.2 Additionally, microarray technology may detect aneuploidy and the presence of mul- tiple genotypes (such as chimerism or mosaicism).2 Allele frequency plots are utilized to detect these anomalies.2 This plot visualizes the fluorescent signal ratio of reference and nonreference alleles, such that a value 1 or 0 in the plot indicates the complete absence of the alternate allele (a homozygous genotype of either reference or nonreference allele), and a value 0.5 indicates the presence of both alleles (the heterozygous state).	cache/ct-12703.pdf	txt/ct-12703.txt