id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ct-9941	Bulkeley, Evelyn; Foutouhi, Azarene; Meyers, Stuart	Rethinking sperm: lessons from mitochondrial function	2019	8	.pdf	application/pdf	4716	240	37	Our recent studies demonstrated that stallion sperm motility is fueled primarily by mitochondrial- produced ATP and that both mitochondrial oxidative function and motility decrease significantly with cryopreservation.5,30 Additionally, cryopreservation alters stallion sperm Ca2+ i signaling and homeostasis,31 known to have important roles in sperm motility.32,33 Because mature sperm lack an intact ER, the predominant intracellular Ca2+ store in most cell types, it was previously believed that influx of extracellular Ca2+ is the sole Ca2+ source and regulator of Ca2+ i homeostasis.34 However, there is now evidence that intracellular Ca2+ stores are present in sperm of several species, including humans, mice and cattle,35,36 but Ca2+ i stores have not yet been identified or characterized in stallion sperm. To explore whether glycolysis alone can support sperm motility, Davila and coworkers28 aimed to inhibit glycolysis by incubating stallion sperm in the presence of 2 deoxy D Glucose (2 DG) rather than glucose.	cache/ct-9941.pdf	txt/ct-9941.txt