id	sid	tid	token	lemma	pos
ct-12609	1	1	2009	2009	NUM
ct-12609	1	2	:	:	PUNCT
ct-12609	1	3	equine	equine	NOUN
ct-12609	1	4	metabolic	metabolic	NOUN
ct-12609	1	5	syndrome	syndrome	NOUN
ct-12609	1	6	and	and	CCONJ
ct-12609	1	7	cushing	cushing	NOUN
ct-12609	1	8	's	's	PART
ct-12609	1	9	disease	disease	NOUN
ct-12609	1	10	:	:	PUNCT
ct-12609	1	11	possible	possible	ADJ
ct-12609	1	12	role	role	NOUN
ct-12609	1	13	in	in	ADP
ct-12609	1	14	infertility	infertility	NOUN
ct-12609	1	15	in	in	ADP
ct-12609	1	16	the	the	DET
ct-12609	1	17	horse	horse	NOUN
ct-12609	1	18	equine	equine	NOUN
ct-12609	1	19	metabolic	metabolic	NOUN
ct-12609	1	20	syndrome	syndrome	NOUN
ct-12609	1	21	and	and	CCONJ
ct-12609	1	22	cushing	cushing	NOUN
ct-12609	1	23	’s	’s	PART
ct-12609	1	24	disease	disease	NOUN
ct-12609	1	25	:	:	PUNCT
ct-12609	1	26	possible	possible	ADJ
ct-12609	1	27	role	role	NOUN
ct-12609	1	28	in	in	ADP
ct-12609	1	29	infertility	infertility	NOUN
ct-12609	1	30	in	in	ADP
ct-12609	1	31	the	the	DET
ct-12609	1	32	horse	horse	NOUN
ct-12609	1	33	m.	m.	NOUN
ct-12609	1	34	e.	e.	PROPN
ct-12609	1	35	cadarioa	cadarioa	PROPN
ct-12609	1	36	,	,	PUNCT
ct-12609	1	37	m.	m.	NOUN
ct-12609	1	38	m.	m.	PROPN
ct-12609	1	39	leblancb	leblancb	PROPN
ct-12609	1	40	againesville	againesville	PROPN
ct-12609	1	41	,	,	PUNCT
ct-12609	1	42	fl	fl	PROPN
ct-12609	1	43	,	,	PUNCT
ct-12609	1	44	usa	usa	PROPN
ct-12609	1	45	;	;	PUNCT
ct-12609	1	46	brood	brood	NOUN
ct-12609	1	47	and	and	CCONJ
ct-12609	1	48	riddle	riddle	VERB
ct-12609	1	49	equine	equine	NOUN
ct-12609	1	50	hospital	hospital	NOUN
ct-12609	1	51	,	,	PUNCT
ct-12609	1	52	po	po	PROPN
ct-12609	1	53	box	box	PROPN
ct-12609	1	54	12090	12090	PROPN
ct-12609	1	55	,	,	PUNCT
ct-12609	1	56	lexington	lexington	PROPN
ct-12609	1	57	,	,	PUNCT
ct-12609	1	58	ky	ky	PROPN
ct-12609	1	59	,	,	PUNCT
ct-12609	1	60	usa	usa	PROPN
ct-12609	1	61	abstract	abstract	PROPN
ct-12609	1	62	over	over	ADP
ct-12609	1	63	the	the	DET
ct-12609	1	64	last	last	ADJ
ct-12609	1	65	several	several	ADJ
ct-12609	1	66	years	year	NOUN
ct-12609	1	67	,	,	PUNCT
ct-12609	1	68	there	there	PRON
ct-12609	1	69	has	have	AUX
ct-12609	1	70	been	be	AUX
ct-12609	1	71	a	a	DET
ct-12609	1	72	clear	clear	ADJ
ct-12609	1	73	increase	increase	NOUN
ct-12609	1	74	in	in	ADP
ct-12609	1	75	the	the	DET
ct-12609	1	76	geriatric	geriatric	ADJ
ct-12609	1	77	horse	horse	NOUN
ct-12609	1	78	population	population	NOUN
ct-12609	1	79	.	.	PUNCT
ct-12609	2	1	some	some	PRON
ct-12609	2	2	of	of	ADP
ct-12609	2	3	those	those	DET
ct-12609	2	4	mares	mare	NOUN
ct-12609	2	5	are	be	AUX
ct-12609	2	6	expected	expect	VERB
ct-12609	2	7	to	to	PART
ct-12609	2	8	become	become	VERB
ct-12609	2	9	donors	donor	NOUN
ct-12609	2	10	for	for	ADP
ct-12609	2	11	embryo	embryo	NOUN
ct-12609	2	12	transfer	transfer	NOUN
ct-12609	2	13	or	or	CCONJ
ct-12609	2	14	to	to	PART
ct-12609	2	15	become	become	VERB
ct-12609	2	16	pregnant	pregnant	ADJ
ct-12609	2	17	,	,	PUNCT
ct-12609	2	18	forgetting	forget	VERB
ct-12609	2	19	the	the	DET
ct-12609	2	20	consequences	consequence	NOUN
ct-12609	2	21	of	of	ADP
ct-12609	2	22	a	a	DET
ct-12609	2	23	long	long	ADJ
ct-12609	2	24	life	life	NOUN
ct-12609	2	25	expectancy	expectancy	NOUN
ct-12609	2	26	.	.	PUNCT
ct-12609	3	1	for	for	ADP
ct-12609	3	2	example	example	NOUN
ct-12609	3	3	;	;	PUNCT
ct-12609	3	4	illnesses	illness	NOUN
ct-12609	3	5	and	and	CCONJ
ct-12609	3	6	problems	problem	NOUN
ct-12609	3	7	that	that	PRON
ct-12609	3	8	commonly	commonly	ADV
ct-12609	3	9	affect	affect	VERB
ct-12609	3	10	the	the	DET
ct-12609	3	11	aged	aged	ADJ
ct-12609	3	12	horse	horse	NOUN
ct-12609	3	13	such	such	ADJ
ct-12609	3	14	as	as	ADP
ct-12609	3	15	cushing	cushing	NOUN
ct-12609	3	16	’s	’s	PART
ct-12609	3	17	disease	disease	NOUN
ct-12609	3	18	(	(	PUNCT
ct-12609	3	19	cd	cd	PROPN
ct-12609	3	20	)	)	PUNCT
ct-12609	3	21	and	and	CCONJ
ct-12609	3	22	equine	equine	NOUN
ct-12609	3	23	metabolic	metabolic	NOUN
ct-12609	3	24	syndrome	syndrome	NOUN
ct-12609	3	25	(	(	PUNCT
ct-12609	3	26	ms	ms	NOUN
ct-12609	3	27	)	)	PUNCT
ct-12609	3	28	have	have	AUX
ct-12609	3	29	become	become	VERB
ct-12609	3	30	more	more	ADV
ct-12609	3	31	prevalent	prevalent	ADJ
ct-12609	3	32	.	.	PUNCT
ct-12609	4	1	these	these	DET
ct-12609	4	2	metabolic	metabolic	NOUN
ct-12609	4	3	conditions	condition	NOUN
ct-12609	4	4	share	share	NOUN
ct-12609	4	5	traits	trait	NOUN
ct-12609	4	6	,	,	PUNCT
ct-12609	4	7	e.g.	e.g.	ADV
ct-12609	4	8	,	,	PUNCT
ct-12609	4	9	insulin	insulin	NOUN
ct-12609	4	10	resistance	resistance	NOUN
ct-12609	4	11	(	(	PUNCT
ct-12609	4	12	ir	ir	NOUN
ct-12609	4	13	)	)	PUNCT
ct-12609	4	14	,	,	PUNCT
ct-12609	4	15	often	often	ADV
ct-12609	4	16	in	in	ADP
ct-12609	4	17	conjunction	conjunction	NOUN
ct-12609	4	18	with	with	ADP
ct-12609	4	19	obesity	obesity	NOUN
ct-12609	4	20	,	,	PUNCT
ct-12609	4	21	which	which	PRON
ct-12609	4	22	have	have	AUX
ct-12609	4	23	been	be	AUX
ct-12609	4	24	associated	associate	VERB
ct-12609	4	25	with	with	ADP
ct-12609	4	26	the	the	DET
ct-12609	4	27	development	development	NOUN
ct-12609	4	28	of	of	ADP
ct-12609	4	29	abnormal	abnormal	ADJ
ct-12609	4	30	reproductive	reproductive	ADJ
ct-12609	4	31	function	function	NOUN
ct-12609	4	32	and	and	CCONJ
ct-12609	4	33	laminitis	laminitis	NOUN
ct-12609	4	34	in	in	ADP
ct-12609	4	35	the	the	DET
ct-12609	4	36	horse	horse	NOUN
ct-12609	4	37	.	.	PUNCT
ct-12609	5	1	a	a	DET
ct-12609	5	2	large	large	ADJ
ct-12609	5	3	number	number	NOUN
ct-12609	5	4	of	of	ADP
ct-12609	5	5	obese	obese	NOUN
ct-12609	5	6	and	and	CCONJ
ct-12609	5	7	ir	ir	PROPN
ct-12609	5	8	mares	mare	NOUN
ct-12609	5	9	continue	continue	VERB
ct-12609	5	10	to	to	PART
ct-12609	5	11	cycle	cycle	VERB
ct-12609	5	12	during	during	ADP
ct-12609	5	13	winter	winter	NOUN
ct-12609	5	14	,	,	PUNCT
ct-12609	5	15	have	have	VERB
ct-12609	5	16	longer	long	ADJ
ct-12609	5	17	inter	inter	ADJ
ct-12609	5	18	-	-	ADJ
ct-12609	5	19	estrus	estrus	ADJ
ct-12609	5	20	intervals	interval	NOUN
ct-12609	5	21	,	,	PUNCT
ct-12609	5	22	prolonged	prolong	VERB
ct-12609	5	23	luteal	luteal	ADJ
ct-12609	5	24	phases	phase	NOUN
ct-12609	5	25	and	and	CCONJ
ct-12609	5	26	a	a	DET
ct-12609	5	27	higher	high	ADJ
ct-12609	5	28	incidence	incidence	NOUN
ct-12609	5	29	of	of	ADP
ct-12609	5	30	anovulatory	anovulatory	NOUN
ct-12609	5	31	follicles	follicle	NOUN
ct-12609	5	32	.	.	PUNCT
ct-12609	6	1	diagnosis	diagnosis	NOUN
ct-12609	6	2	of	of	ADP
ct-12609	6	3	ms	ms	NOUN
ct-12609	6	4	or	or	CCONJ
ct-12609	6	5	cd	cd	PROPN
ct-12609	6	6	requires	require	VERB
ct-12609	6	7	a	a	DET
ct-12609	6	8	good	good	ADJ
ct-12609	6	9	clinical	clinical	ADJ
ct-12609	6	10	assessment	assessment	NOUN
ct-12609	6	11	in	in	ADP
ct-12609	6	12	combination	combination	NOUN
ct-12609	6	13	with	with	ADP
ct-12609	6	14	the	the	DET
ct-12609	6	15	proper	proper	ADJ
ct-12609	6	16	laboratory	laboratory	NOUN
ct-12609	6	17	testing	testing	NOUN
ct-12609	6	18	.	.	PUNCT
ct-12609	7	1	once	once	ADV
ct-12609	7	2	identified	identify	VERB
ct-12609	7	3	,	,	PUNCT
ct-12609	7	4	ms	ms	PROPN
ct-12609	7	5	should	should	AUX
ct-12609	7	6	be	be	AUX
ct-12609	7	7	managed	manage	VERB
ct-12609	7	8	with	with	ADP
ct-12609	7	9	a	a	DET
ct-12609	7	10	diet	diet	NOUN
ct-12609	7	11	poor	poor	ADJ
ct-12609	7	12	in	in	ADP
ct-12609	7	13	carbohydrates	carbohydrate	NOUN
ct-12609	7	14	and	and	CCONJ
ct-12609	7	15	an	an	DET
ct-12609	7	16	exercise	exercise	NOUN
ct-12609	7	17	program	program	NOUN
ct-12609	7	18	that	that	PRON
ct-12609	7	19	stresses	stress	VERB
ct-12609	7	20	a	a	DET
ct-12609	7	21	moderate	moderate	ADJ
ct-12609	7	22	body	body	NOUN
ct-12609	7	23	condition	condition	NOUN
ct-12609	7	24	.	.	PUNCT
ct-12609	8	1	treatment	treatment	NOUN
ct-12609	8	2	for	for	ADP
ct-12609	8	3	cd	cd	PROPN
ct-12609	8	4	comprises	comprise	VERB
ct-12609	8	5	appropriate	appropriate	ADJ
ct-12609	8	6	health	health	NOUN
ct-12609	8	7	care	care	NOUN
ct-12609	8	8	and	and	CCONJ
ct-12609	8	9	the	the	DET
ct-12609	8	10	administration	administration	NOUN
ct-12609	8	11	of	of	ADP
ct-12609	8	12	pergolide	pergolide	NOUN
ct-12609	8	13	,	,	PUNCT
ct-12609	8	14	cyproheptadine	cyproheptadine	NOUN
ct-12609	8	15	or	or	CCONJ
ct-12609	8	16	a	a	DET
ct-12609	8	17	combination	combination	NOUN
ct-12609	8	18	.	.	PUNCT
ct-12609	9	1	even	even	ADV
ct-12609	9	2	though	though	SCONJ
ct-12609	9	3	a	a	DET
ct-12609	9	4	link	link	NOUN
ct-12609	9	5	between	between	ADP
ct-12609	9	6	infertility	infertility	NOUN
ct-12609	9	7	and	and	CCONJ
ct-12609	9	8	these	these	DET
ct-12609	9	9	metabolic	metabolic	NOUN
ct-12609	9	10	conditions	condition	NOUN
ct-12609	9	11	has	have	AUX
ct-12609	9	12	been	be	AUX
ct-12609	9	13	established	establish	VERB
ct-12609	9	14	,	,	PUNCT
ct-12609	9	15	there	there	PRON
ct-12609	9	16	is	be	VERB
ct-12609	9	17	a	a	DET
ct-12609	9	18	clear	clear	ADJ
ct-12609	9	19	need	need	NOUN
ct-12609	9	20	for	for	ADP
ct-12609	9	21	further	further	ADJ
ct-12609	9	22	investigation	investigation	NOUN
ct-12609	9	23	.	.	PUNCT
ct-12609	10	1	keywords	keyword	NOUN
ct-12609	10	2	:	:	PUNCT
ct-12609	10	3	cushing	cushe	VERB
ct-12609	10	4	’s	’s	PART
ct-12609	10	5	disease	disease	NOUN
ct-12609	10	6	,	,	PUNCT
ct-12609	10	7	metabolic	metabolic	NOUN
ct-12609	10	8	syndrome	syndrome	NOUN
ct-12609	10	9	,	,	PUNCT
ct-12609	10	10	insulin	insulin	NOUN
ct-12609	10	11	resistance	resistance	NOUN
ct-12609	10	12	,	,	PUNCT
ct-12609	10	13	infertility	infertility	NOUN
ct-12609	10	14	,	,	PUNCT
ct-12609	10	15	mare	mare	NOUN
ct-12609	10	16	485	485	NUM
ct-12609	10	17	introduction	introduction	NOUN
ct-12609	10	18	several	several	ADJ
ct-12609	10	19	endocrine	endocrine	NOUN
ct-12609	10	20	and	and	CCONJ
ct-12609	10	21	metabolic	metabolic	NOUN
ct-12609	10	22	conditions	condition	NOUN
ct-12609	10	23	had	have	AUX
ct-12609	10	24	been	be	AUX
ct-12609	10	25	empirically	empirically	ADV
ct-12609	10	26	linked	link	VERB
ct-12609	10	27	to	to	ADP
ct-12609	10	28	infertility	infertility	NOUN
ct-12609	10	29	in	in	ADP
ct-12609	10	30	the	the	DET
ct-12609	10	31	mare	mare	NOUN
ct-12609	10	32	including	include	VERB
ct-12609	10	33	hypothyroidism	hypothyroidism	NOUN
ct-12609	10	34	,	,	PUNCT
ct-12609	10	35	metabolic	metabolic	NOUN
ct-12609	10	36	syndrome	syndrome	NOUN
ct-12609	10	37	(	(	PUNCT
ct-12609	10	38	ms	ms	ADJ
ct-12609	10	39	-	-	PUNCT
ct-12609	10	40	insulin	insulin	NOUN
ct-12609	10	41	resistance	resistance	NOUN
ct-12609	10	42	)	)	PUNCT
ct-12609	10	43	and	and	CCONJ
ct-12609	10	44	cushing	cushing	NOUN
ct-12609	10	45	’s	’s	PART
ct-12609	10	46	disease	disease	NOUN
ct-12609	10	47	(	(	PUNCT
ct-12609	10	48	cd	cd	PROPN
ct-12609	10	49	)	)	PUNCT
ct-12609	10	50	or	or	CCONJ
ct-12609	10	51	pituitary	pituitary	ADJ
ct-12609	10	52	pars	par	NOUN
ct-12609	10	53	intermedia	intermedia	PROPN
ct-12609	10	54	disease	disease	PROPN
ct-12609	10	55	(	(	PUNCT
ct-12609	10	56	ppid	ppid	NOUN
ct-12609	10	57	)	)	PUNCT
ct-12609	10	58	.	.	PUNCT
ct-12609	11	1	the	the	DET
ct-12609	11	2	mechanisms	mechanism	NOUN
ct-12609	11	3	by	by	ADP
ct-12609	11	4	which	which	PRON
ct-12609	11	5	these	these	DET
ct-12609	11	6	conditions	condition	NOUN
ct-12609	11	7	lead	lead	VERB
ct-12609	11	8	to	to	ADP
ct-12609	11	9	infertility	infertility	NOUN
ct-12609	11	10	are	be	AUX
ct-12609	11	11	not	not	PART
ct-12609	11	12	completely	completely	ADV
ct-12609	11	13	understood	understand	VERB
ct-12609	11	14	.	.	PUNCT
ct-12609	12	1	these	these	DET
ct-12609	12	2	metabolic	metabolic	NOUN
ct-12609	12	3	aberrations	aberration	NOUN
ct-12609	12	4	are	be	AUX
ct-12609	12	5	gaining	gain	VERB
ct-12609	12	6	attention	attention	NOUN
ct-12609	12	7	by	by	ADP
ct-12609	12	8	veterinary	veterinary	ADJ
ct-12609	12	9	scientists	scientist	NOUN
ct-12609	12	10	and	and	CCONJ
ct-12609	12	11	equine	equine	NOUN
ct-12609	12	12	nutritionists	nutritionist	NOUN
ct-12609	12	13	as	as	ADP
ct-12609	12	14	the	the	DET
ct-12609	12	15	population	population	NOUN
ct-12609	12	16	of	of	ADP
ct-12609	12	17	geriatric	geriatric	PROPN
ct-12609	12	18	,	,	PUNCT
ct-12609	12	19	obese	obese	ADJ
ct-12609	12	20	horses	horse	NOUN
ct-12609	12	21	in	in	ADP
ct-12609	12	22	the	the	DET
ct-12609	12	23	usa	usa	PROPN
ct-12609	12	24	is	be	AUX
ct-12609	12	25	increasing	increase	VERB
ct-12609	12	26	and	and	CCONJ
ct-12609	12	27	owners	owner	NOUN
ct-12609	12	28	are	be	AUX
ct-12609	12	29	requesting	request	VERB
ct-12609	12	30	additional	additional	ADJ
ct-12609	12	31	care	care	NOUN
ct-12609	12	32	for	for	ADP
ct-12609	12	33	affected	affected	ADJ
ct-12609	12	34	horses	horse	NOUN
ct-12609	12	35	.	.	PUNCT
ct-12609	13	1	this	this	DET
ct-12609	13	2	review	review	NOUN
ct-12609	13	3	discusses	discuss	VERB
ct-12609	13	4	the	the	DET
ct-12609	13	5	pathophysiology	pathophysiology	NOUN
ct-12609	13	6	of	of	ADP
ct-12609	13	7	ms	ms	PROPN
ct-12609	13	8	and	and	CCONJ
ct-12609	13	9	cd	cd	PROPN
ct-12609	13	10	,	,	PUNCT
ct-12609	13	11	how	how	SCONJ
ct-12609	13	12	they	they	PRON
ct-12609	13	13	may	may	AUX
ct-12609	13	14	adversely	adversely	ADV
ct-12609	13	15	affect	affect	VERB
ct-12609	13	16	fertility	fertility	NOUN
ct-12609	13	17	,	,	PUNCT
ct-12609	13	18	diagnostics	diagnostic	NOUN
ct-12609	13	19	and	and	CCONJ
ct-12609	13	20	recommended	recommend	VERB
ct-12609	13	21	therapies	therapy	NOUN
ct-12609	13	22	.	.	PUNCT
ct-12609	14	1	during	during	ADP
ct-12609	14	2	the	the	DET
ct-12609	14	3	fall	fall	NOUN
ct-12609	14	4	months	month	NOUN
ct-12609	14	5	and	and	CCONJ
ct-12609	14	6	in	in	ADP
ct-12609	14	7	preparation	preparation	NOUN
ct-12609	14	8	for	for	ADP
ct-12609	14	9	winter	winter	NOUN
ct-12609	14	10	,	,	PUNCT
ct-12609	14	11	the	the	DET
ct-12609	14	12	horse	horse	NOUN
ct-12609	14	13	begins	begin	VERB
ct-12609	14	14	to	to	PART
ct-12609	14	15	store	store	VERB
ct-12609	14	16	energy	energy	NOUN
ct-12609	14	17	in	in	ADP
ct-12609	14	18	the	the	DET
ct-12609	14	19	form	form	NOUN
ct-12609	14	20	of	of	ADP
ct-12609	14	21	body	body	NOUN
ct-12609	14	22	fat	fat	ADJ
ct-12609	14	23	.	.	PUNCT
ct-12609	15	1	the	the	DET
ct-12609	15	2	process	process	NOUN
ct-12609	15	3	is	be	AUX
ct-12609	15	4	controlled	control	VERB
ct-12609	15	5	by	by	ADP
ct-12609	15	6	the	the	DET
ct-12609	15	7	hypothalamic	hypothalamic	ADJ
ct-12609	15	8	-	-	PUNCT
ct-12609	15	9	pituitary	pituitary	ADJ
ct-12609	15	10	axis	axis	NOUN
ct-12609	15	11	as	as	SCONJ
ct-12609	15	12	it	it	PRON
ct-12609	15	13	induces	induce	VERB
ct-12609	15	14	an	an	DET
ct-12609	15	15	increased	increase	VERB
ct-12609	15	16	secretion	secretion	NOUN
ct-12609	15	17	of	of	ADP
ct-12609	15	18	pro	pro	ADJ
ct-12609	15	19	-	-	ADJ
ct-12609	15	20	opiomelanocortin	opiomelanocortin	ADJ
ct-12609	15	21	peptides1	peptides1	NOUN
ct-12609	15	22	and	and	CCONJ
ct-12609	15	23	results	result	NOUN
ct-12609	15	24	in	in	ADP
ct-12609	15	25	an	an	DET
ct-12609	15	26	increase	increase	NOUN
ct-12609	15	27	in	in	ADP
ct-12609	15	28	appetite	appetite	NOUN
ct-12609	15	29	and	and	CCONJ
ct-12609	15	30	adipogenesis	adipogenesis	NOUN
ct-12609	15	31	in	in	ADP
ct-12609	15	32	conjunction	conjunction	NOUN
ct-12609	15	33	with	with	ADP
ct-12609	15	34	the	the	DET
ct-12609	15	35	development	development	NOUN
ct-12609	15	36	of	of	ADP
ct-12609	15	37	a	a	DET
ct-12609	15	38	thick	thick	ADJ
ct-12609	15	39	hair	hair	NOUN
ct-12609	15	40	coat	coat	NOUN
ct-12609	15	41	.	.	PUNCT
ct-12609	16	1	this	this	DET
ct-12609	16	2	“	"	PUNCT
ct-12609	16	3	survival	survival	NOUN
ct-12609	16	4	mechanism	mechanism	NOUN
ct-12609	16	5	”	"	PUNCT
ct-12609	16	6	,	,	PUNCT
ct-12609	16	7	disappears	disappear	VERB
ct-12609	16	8	by	by	ADP
ct-12609	16	9	the	the	DET
ct-12609	16	10	end	end	NOUN
ct-12609	16	11	of	of	ADP
ct-12609	16	12	winter	winter	NOUN
ct-12609	16	13	in	in	ADP
ct-12609	16	14	healthy	healthy	ADJ
ct-12609	16	15	horses	horse	NOUN
ct-12609	16	16	but	but	CCONJ
ct-12609	16	17	not	not	PART
ct-12609	16	18	in	in	ADP
ct-12609	16	19	horses	horse	NOUN
ct-12609	16	20	with	with	ADP
ct-12609	16	21	ms	ms	PROPN
ct-12609	16	22	or	or	CCONJ
ct-12609	16	23	cd	cd	PROPN
ct-12609	16	24	.	.	PUNCT
ct-12609	16	25	metabolic	metabolic	NOUN
ct-12609	16	26	synrrome	synrrome	NOUN
ct-12609	16	27	and	and	CCONJ
ct-12609	16	28	,	,	PUNCT
ct-12609	16	29	to	to	ADP
ct-12609	16	30	a	a	DET
ct-12609	16	31	certain	certain	ADJ
ct-12609	16	32	degree	degree	NOUN
ct-12609	16	33	cd	cd	PROPN
ct-12609	16	34	,	,	PUNCT
ct-12609	16	35	are	be	AUX
ct-12609	16	36	associated	associate	VERB
ct-12609	16	37	with	with	ADP
ct-12609	16	38	the	the	DET
ct-12609	16	39	acquisition	acquisition	NOUN
ct-12609	16	40	of	of	ADP
ct-12609	16	41	excessive	excessive	ADJ
ct-12609	16	42	fat	fat	NOUN
ct-12609	16	43	and	and	CCONJ
ct-12609	16	44	,	,	PUNCT
ct-12609	16	45	more	more	ADV
ct-12609	16	46	importantly	importantly	ADV
ct-12609	16	47	,	,	PUNCT
ct-12609	16	48	the	the	DET
ct-12609	16	49	persistence	persistence	NOUN
ct-12609	16	50	of	of	ADP
ct-12609	16	51	body	body	NOUN
ct-12609	16	52	fat	fat	NOUN
ct-12609	16	53	and	and	CCONJ
ct-12609	16	54	its	its	PRON
ct-12609	16	55	negative	negative	ADJ
ct-12609	16	56	consequences	consequence	NOUN
ct-12609	16	57	on	on	ADP
ct-12609	16	58	the	the	DET
ct-12609	16	59	mare	mare	NOUN
ct-12609	16	60	’s	’s	PART
ct-12609	16	61	general	general	PROPN
ct-12609	16	62	heath	heath	PROPN
ct-12609	16	63	and	and	CCONJ
ct-12609	16	64	reproduction.2	reproduction.2	PROPN
ct-12609	16	65	clinical	clinical	ADJ
ct-12609	16	66	findings	finding	NOUN
ct-12609	16	67	that	that	PRON
ct-12609	16	68	should	should	AUX
ct-12609	16	69	make	make	VERB
ct-12609	16	70	one	one	NOUN
ct-12609	16	71	suspicious	suspicious	ADJ
ct-12609	16	72	of	of	ADP
ct-12609	16	73	ms	ms	NOUN
ct-12609	16	74	or	or	CCONJ
ct-12609	16	75	cd	cd	PROPN
ct-12609	16	76	include	include	VERB
ct-12609	16	77	obesity	obesity	NOUN
ct-12609	16	78	in	in	ADP
ct-12609	16	79	older	old	ADJ
ct-12609	16	80	horses	horse	NOUN
ct-12609	16	81	that	that	PRON
ct-12609	16	82	do	do	AUX
ct-12609	16	83	not	not	PART
ct-12609	16	84	shed	shed	VERB
ct-12609	16	85	their	their	PRON
ct-12609	16	86	winter	winter	NOUN
ct-12609	16	87	coats	coat	NOUN
ct-12609	16	88	completely	completely	ADV
ct-12609	16	89	or	or	CCONJ
ct-12609	16	90	do	do	VERB
ct-12609	16	91	so	so	ADV
ct-12609	16	92	much	much	ADV
ct-12609	16	93	later	later	ADV
ct-12609	16	94	in	in	ADP
ct-12609	16	95	the	the	DET
ct-12609	16	96	spring	spring	NOUN
ct-12609	16	97	than	than	ADP
ct-12609	16	98	the	the	DET
ct-12609	16	99	remainder	remainder	NOUN
ct-12609	16	100	of	of	ADP
ct-12609	16	101	the	the	DET
ct-12609	16	102	herd	herd	NOUN
ct-12609	16	103	,	,	PUNCT
ct-12609	16	104	abnormal	abnormal	ADJ
ct-12609	16	105	estrous	estrous	ADJ
ct-12609	16	106	cycles	cycle	NOUN
ct-12609	16	107	,	,	PUNCT
ct-12609	16	108	anovulatory	anovulatory	NOUN
ct-12609	16	109	follicles	follicle	NOUN
ct-12609	16	110	and	and	CCONJ
ct-12609	16	111	repeated	repeat	VERB
ct-12609	16	112	bouts	bout	NOUN
ct-12609	16	113	of	of	ADP
ct-12609	16	114	endometritis	endometritis	NOUN
ct-12609	16	115	.	.	PUNCT
ct-12609	17	1	a	a	DET
ct-12609	17	2	number	number	NOUN
ct-12609	17	3	of	of	ADP
ct-12609	17	4	tests	test	NOUN
ct-12609	17	5	are	be	AUX
ct-12609	17	6	available	available	ADJ
ct-12609	17	7	for	for	ADP
ct-12609	17	8	diagnosing	diagnose	VERB
ct-12609	17	9	ms	ms	NOUN
ct-12609	17	10	or	or	CCONJ
ct-12609	17	11	cd	cd	PROPN
ct-12609	17	12	.	.	PUNCT
ct-12609	18	1	however	however	ADV
ct-12609	18	2	,	,	PUNCT
ct-12609	18	3	there	there	PRON
ct-12609	18	4	is	be	VERB
ct-12609	18	5	no	no	DET
ct-12609	18	6	single	single	ADJ
ct-12609	18	7	“	"	PUNCT
ct-12609	18	8	gold	gold	ADJ
ct-12609	18	9	standard	standard	NOUN
ct-12609	18	10	”	"	PUNCT
ct-12609	18	11	.	.	PUNCT
ct-12609	19	1	486	486	NUM
ct-12609	19	2	equine	equine	NOUN
ct-12609	19	3	metabolic	metabolic	NOUN
ct-12609	19	4	syndrome	syndrome	NOUN
ct-12609	19	5	equine	equine	NOUN
ct-12609	19	6	ms	ms	NOUN
ct-12609	19	7	is	be	AUX
ct-12609	19	8	closely	closely	ADV
ct-12609	19	9	associated	associate	VERB
ct-12609	19	10	with	with	ADP
ct-12609	19	11	two	two	NUM
ct-12609	19	12	disorders	disorder	NOUN
ct-12609	19	13	:	:	PUNCT
ct-12609	19	14	obesity	obesity	NOUN
ct-12609	19	15	and	and	CCONJ
ct-12609	19	16	insulin	insulin	NOUN
ct-12609	19	17	resistance	resistance	NOUN
ct-12609	19	18	(	(	PUNCT
ct-12609	19	19	ir	ir	NOUN
ct-12609	19	20	or	or	CCONJ
ct-12609	19	21	glucose	glucose	NOUN
ct-12609	19	22	intolerance	intolerance	NOUN
ct-12609	19	23	)	)	PUNCT
ct-12609	19	24	.	.	PUNCT
ct-12609	20	1	horses	horse	NOUN
ct-12609	20	2	affected	affect	VERB
ct-12609	20	3	with	with	ADP
ct-12609	20	4	ms	ms	PROPN
ct-12609	20	5	also	also	ADV
ct-12609	20	6	have	have	VERB
ct-12609	20	7	a	a	DET
ct-12609	20	8	predisposition	predisposition	NOUN
ct-12609	20	9	to	to	ADP
ct-12609	20	10	developing	develop	VERB
ct-12609	20	11	laminitis	laminitis	NOUN
ct-12609	20	12	and	and	CCONJ
ct-12609	20	13	mares	mare	NOUN
ct-12609	20	14	may	may	AUX
ct-12609	20	15	exhibit	exhibit	VERB
ct-12609	20	16	abnormal	abnormal	ADJ
ct-12609	20	17	estrous	estrous	ADJ
ct-12609	20	18	cycles.3	cycles.3	NOUN
ct-12609	20	19	the	the	DET
ct-12609	20	20	obesity	obesity	NOUN
ct-12609	20	21	is	be	AUX
ct-12609	20	22	evident	evident	ADJ
ct-12609	20	23	as	as	ADP
ct-12609	20	24	subcutaneous	subcutaneous	ADJ
ct-12609	20	25	regional	regional	ADJ
ct-12609	20	26	adiposity	adiposity	NOUN
ct-12609	20	27	(	(	PUNCT
ct-12609	20	28	“	"	PUNCT
ct-12609	20	29	cresty	cresty	NOUN
ct-12609	20	30	neck	neck	NOUN
ct-12609	20	31	”	"	PUNCT
ct-12609	20	32	,	,	PUNCT
ct-12609	20	33	tailhead	tailhead	NOUN
ct-12609	20	34	,	,	PUNCT
ct-12609	20	35	shoulders	shoulder	NOUN
ct-12609	20	36	and	and	CCONJ
ct-12609	20	37	prepuce	prepuce	NOUN
ct-12609	20	38	in	in	ADP
ct-12609	20	39	geldings	gelding	NOUN
ct-12609	20	40	)	)	PUNCT
ct-12609	20	41	and	and	CCONJ
ct-12609	20	42	affected	affect	VERB
ct-12609	20	43	horses	horse	NOUN
ct-12609	20	44	tend	tend	VERB
ct-12609	20	45	to	to	PART
ct-12609	20	46	be	be	AUX
ct-12609	20	47	genetically	genetically	ADV
ct-12609	20	48	predisposed	predispose	VERB
ct-12609	20	49	requiring	require	VERB
ct-12609	20	50	fewer	few	ADJ
ct-12609	20	51	calories	calorie	NOUN
ct-12609	20	52	to	to	PART
ct-12609	20	53	keep	keep	VERB
ct-12609	20	54	normal	normal	ADJ
ct-12609	20	55	body	body	NOUN
ct-12609	20	56	weight	weight	NOUN
ct-12609	20	57	(	(	PUNCT
ct-12609	20	58	“	"	PUNCT
ct-12609	20	59	easy	easy	ADJ
ct-12609	20	60	keepers	keeper	NOUN
ct-12609	20	61	”	"	PUNCT
ct-12609	20	62	)	)	PUNCT
ct-12609	20	63	.	.	PUNCT
ct-12609	21	1	not	not	PART
ct-12609	21	2	all	all	DET
ct-12609	21	3	obese	obese	ADJ
ct-12609	21	4	horses	horse	NOUN
ct-12609	21	5	have	have	VERB
ct-12609	21	6	ir	ir	NOUN
ct-12609	21	7	even	even	ADV
ct-12609	21	8	though	though	SCONJ
ct-12609	21	9	obesity	obesity	NOUN
ct-12609	21	10	increases	increase	VERB
ct-12609	21	11	the	the	DET
ct-12609	21	12	horse	horse	NOUN
ct-12609	21	13	’s	’s	PART
ct-12609	21	14	risk	risk	NOUN
ct-12609	21	15	of	of	ADP
ct-12609	21	16	developing	develop	VERB
ct-12609	21	17	the	the	DET
ct-12609	21	18	disease	disease	NOUN
ct-12609	21	19	.	.	PUNCT
ct-12609	22	1	some	some	DET
ct-12609	22	2	breeds	breed	NOUN
ct-12609	22	3	appear	appear	VERB
ct-12609	22	4	to	to	PART
ct-12609	22	5	be	be	AUX
ct-12609	22	6	more	more	ADV
ct-12609	22	7	commonly	commonly	ADV
ct-12609	22	8	affected	affect	VERB
ct-12609	22	9	than	than	ADP
ct-12609	22	10	others	other	NOUN
ct-12609	22	11	,	,	PUNCT
ct-12609	22	12	including	include	VERB
ct-12609	22	13	ponies	pony	NOUN
ct-12609	22	14	,	,	PUNCT
ct-12609	22	15	quarter	quarter	NOUN
ct-12609	22	16	horses	horse	NOUN
ct-12609	22	17	,	,	PUNCT
ct-12609	22	18	morgans	morgan	NOUN
ct-12609	22	19	,	,	PUNCT
ct-12609	22	20	arabians	arabian	NOUN
ct-12609	22	21	and	and	CCONJ
ct-12609	22	22	saddlebreds	saddlebred	NOUN
ct-12609	22	23	.	.	PUNCT
ct-12609	23	1	there	there	PRON
ct-12609	23	2	is	be	VERB
ct-12609	23	3	no	no	DET
ct-12609	23	4	gender	gender	NOUN
ct-12609	23	5	bias.4	bias.4	ADJ
ct-12609	23	6	pathophysiology	pathophysiology	NOUN
ct-12609	23	7	:	:	PUNCT
ct-12609	23	8	when	when	SCONJ
ct-12609	23	9	foods	food	NOUN
ct-12609	23	10	rich	rich	ADJ
ct-12609	23	11	in	in	ADP
ct-12609	23	12	carbohydrates	carbohydrate	NOUN
ct-12609	23	13	are	be	AUX
ct-12609	23	14	ingested	ingest	VERB
ct-12609	23	15	,	,	PUNCT
ct-12609	23	16	they	they	PRON
ct-12609	23	17	are	be	AUX
ct-12609	23	18	broken	break	VERB
ct-12609	23	19	down	down	ADP
ct-12609	23	20	into	into	ADP
ct-12609	23	21	glucose	glucose	NOUN
ct-12609	23	22	.	.	PUNCT
ct-12609	24	1	this	this	PRON
ct-12609	24	2	is	be	AUX
ct-12609	24	3	followed	follow	VERB
ct-12609	24	4	by	by	ADP
ct-12609	24	5	a	a	DET
ct-12609	24	6	physiological	physiological	ADJ
ct-12609	24	7	hyperglycemia	hyperglycemia	NOUN
ct-12609	24	8	which	which	PRON
ct-12609	24	9	triggers	trigger	VERB
ct-12609	24	10	the	the	DET
ct-12609	24	11	release	release	NOUN
ct-12609	24	12	of	of	ADP
ct-12609	24	13	insulin	insulin	NOUN
ct-12609	24	14	from	from	ADP
ct-12609	24	15	the	the	DET
ct-12609	24	16	pancreas	pancrea	NOUN
ct-12609	24	17	.	.	PUNCT
ct-12609	25	1	insulin	insulin	NOUN
ct-12609	25	2	promotes	promote	VERB
ct-12609	25	3	glucose	glucose	NOUN
ct-12609	25	4	uptake	uptake	NOUN
ct-12609	25	5	by	by	ADP
ct-12609	25	6	cells	cell	NOUN
ct-12609	25	7	.	.	PUNCT
ct-12609	26	1	once	once	ADV
ct-12609	26	2	in	in	ADP
ct-12609	26	3	the	the	DET
ct-12609	26	4	cell	cell	NOUN
ct-12609	26	5	,	,	PUNCT
ct-12609	26	6	glucose	glucose	NOUN
ct-12609	26	7	is	be	AUX
ct-12609	26	8	either	either	CCONJ
ct-12609	26	9	used	use	VERB
ct-12609	26	10	immediately	immediately	ADV
ct-12609	26	11	or	or	CCONJ
ct-12609	26	12	it	it	PRON
ct-12609	26	13	is	be	AUX
ct-12609	26	14	stored	store	VERB
ct-12609	26	15	as	as	ADP
ct-12609	26	16	glycogen	glycogen	NOUN
ct-12609	26	17	or	or	CCONJ
ct-12609	26	18	fat	fat	NOUN
ct-12609	26	19	.	.	PUNCT
ct-12609	27	1	the	the	DET
ct-12609	27	2	amount	amount	NOUN
ct-12609	27	3	of	of	ADP
ct-12609	27	4	insulin	insulin	NOUN
ct-12609	27	5	required	require	VERB
ct-12609	27	6	for	for	ADP
ct-12609	27	7	inducing	induce	VERB
ct-12609	27	8	glucose	glucose	NOUN
ct-12609	27	9	uptake	uptake	NOUN
ct-12609	27	10	into	into	ADP
ct-12609	27	11	cells	cell	NOUN
ct-12609	27	12	is	be	AUX
ct-12609	27	13	tightly	tightly	ADV
ct-12609	27	14	regulated	regulate	VERB
ct-12609	27	15	and	and	CCONJ
ct-12609	27	16	is	be	AUX
ct-12609	27	17	referred	refer	VERB
ct-12609	27	18	to	to	ADP
ct-12609	27	19	as	as	ADP
ct-12609	27	20	insulin	insulin	NOUN
ct-12609	27	21	sensitivity	sensitivity	NOUN
ct-12609	27	22	.	.	PUNCT
ct-12609	28	1	if	if	SCONJ
ct-12609	28	2	a	a	DET
ct-12609	28	3	horse	horse	NOUN
ct-12609	28	4	develops	develop	VERB
ct-12609	28	5	ir	ir	PROPN
ct-12609	28	6	,	,	PUNCT
ct-12609	28	7	there	there	PRON
ct-12609	28	8	is	be	VERB
ct-12609	28	9	a	a	DET
ct-12609	28	10	reduction	reduction	NOUN
ct-12609	28	11	in	in	ADP
ct-12609	28	12	the	the	DET
ct-12609	28	13	insulin	insulin	NOUN
ct-12609	28	14	driven	drive	VERB
ct-12609	28	15	uptake	uptake	NOUN
ct-12609	28	16	of	of	ADP
ct-12609	28	17	glucose	glucose	NOUN
ct-12609	28	18	by	by	ADP
ct-12609	28	19	the	the	DET
ct-12609	28	20	skeletal	skeletal	ADJ
ct-12609	28	21	and	and	CCONJ
ct-12609	28	22	adipose	adipose	PRON
ct-12609	28	23	tissue	tissue	NOUN
ct-12609	28	24	creating	create	VERB
ct-12609	28	25	hyperglycemia.2,4	hyperglycemia.2,4	PROPN
ct-12609	28	26	this	this	PRON
ct-12609	28	27	,	,	PUNCT
ct-12609	28	28	in	in	ADP
ct-12609	28	29	turn	turn	NOUN
ct-12609	28	30	,	,	PUNCT
ct-12609	28	31	generates	generate	VERB
ct-12609	28	32	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	28	33	in	in	ADP
ct-12609	28	34	an	an	DET
ct-12609	28	35	effort	effort	NOUN
ct-12609	28	36	by	by	ADP
ct-12609	28	37	the	the	DET
ct-12609	28	38	pancreas	pancreas	NOUN
ct-12609	28	39	to	to	PART
ct-12609	28	40	compensate	compensate	VERB
ct-12609	28	41	for	for	ADP
ct-12609	28	42	the	the	DET
ct-12609	28	43	insensitivity	insensitivity	NOUN
ct-12609	28	44	.	.	PUNCT
ct-12609	29	1	little	little	ADJ
ct-12609	29	2	is	be	AUX
ct-12609	29	3	known	know	VERB
ct-12609	29	4	about	about	ADP
ct-12609	29	5	the	the	DET
ct-12609	29	6	factors	factor	NOUN
ct-12609	29	7	predisposing	predispose	VERB
ct-12609	29	8	to	to	ADP
ct-12609	29	9	ir	ir	PROPN
ct-12609	29	10	;	;	PUNCT
ct-12609	29	11	however	however	ADV
ct-12609	29	12	,	,	PUNCT
ct-12609	29	13	obesity	obesity	NOUN
ct-12609	29	14	appears	appear	VERB
ct-12609	29	15	to	to	PART
ct-12609	29	16	be	be	AUX
ct-12609	29	17	the	the	DET
ct-12609	29	18	recurrent	recurrent	ADJ
ct-12609	29	19	trait	trait	NOUN
ct-12609	29	20	in	in	ADP
ct-12609	29	21	horses	horse	NOUN
ct-12609	29	22	.	.	PUNCT
ct-12609	30	1	it	it	PRON
ct-12609	30	2	has	have	AUX
ct-12609	30	3	been	be	AUX
ct-12609	30	4	suggested	suggest	VERB
ct-12609	30	5	that	that	SCONJ
ct-12609	30	6	certain	certain	ADJ
ct-12609	30	7	adipocites	adipocite	NOUN
ct-12609	30	8	behave	behave	VERB
ct-12609	30	9	as	as	ADP
ct-12609	30	10	endocrine	endocrine	ADJ
ct-12609	30	11	tissue	tissue	NOUN
ct-12609	30	12	releasing	release	VERB
ct-12609	30	13	cortisol	cortisol	NOUN
ct-12609	30	14	,	,	PUNCT
ct-12609	30	15	pro	pro	ADJ
ct-12609	30	16	-	-	ADJ
ct-12609	30	17	inflammatory	inflammatory	ADJ
ct-12609	30	18	cytokines	cytokine	NOUN
ct-12609	30	19	and	and	CCONJ
ct-12609	30	20	leptin	leptin	NOUN
ct-12609	30	21	,	,	PUNCT
ct-12609	30	22	which	which	PRON
ct-12609	30	23	may	may	AUX
ct-12609	30	24	interfere	interfere	VERB
ct-12609	30	25	with	with	ADP
ct-12609	30	26	glucose	glucose	NOUN
ct-12609	30	27	uptake	uptake	NOUN
ct-12609	30	28	by	by	ADP
ct-12609	30	29	the	the	DET
ct-12609	30	30	cells.2	cells.2	NOUN
ct-12609	30	31	age	age	NOUN
ct-12609	30	32	and	and	CCONJ
ct-12609	30	33	diet	diet	NOUN
ct-12609	30	34	appear	appear	VERB
ct-12609	30	35	to	to	PART
ct-12609	30	36	be	be	AUX
ct-12609	30	37	important	important	ADJ
ct-12609	30	38	contributing	contribute	VERB
ct-12609	30	39	factors	factor	NOUN
ct-12609	30	40	to	to	ADP
ct-12609	30	41	the	the	DET
ct-12609	30	42	development	development	NOUN
ct-12609	30	43	of	of	ADP
ct-12609	30	44	ir	ir	PROPN
ct-12609	30	45	.	.	PUNCT
ct-12609	30	46	ageing	ageing	NOUN
ct-12609	30	47	is	be	AUX
ct-12609	30	48	believed	believe	VERB
ct-12609	30	49	to	to	PART
ct-12609	30	50	decrease	decrease	VERB
ct-12609	30	51	sensitivity	sensitivity	NOUN
ct-12609	30	52	to	to	ADP
ct-12609	30	53	insulin	insulin	NOUN
ct-12609	30	54	.	.	PUNCT
ct-12609	31	1	487	487	NUM
ct-12609	31	2	obesity	obesity	NOUN
ct-12609	31	3	in	in	ADP
ct-12609	31	4	horses	horse	NOUN
ct-12609	31	5	and	and	CCONJ
ct-12609	31	6	especially	especially	ADV
ct-12609	31	7	in	in	ADP
ct-12609	31	8	ponies	pony	NOUN
ct-12609	31	9	appears	appear	VERB
ct-12609	31	10	to	to	PART
ct-12609	31	11	be	be	AUX
ct-12609	31	12	a	a	DET
ct-12609	31	13	risk	risk	NOUN
ct-12609	31	14	factor	factor	NOUN
ct-12609	31	15	for	for	ADP
ct-12609	31	16	mild	mild	ADJ
ct-12609	31	17	laminitis	laminitis	NOUN
ct-12609	31	18	.	.	PUNCT
ct-12609	32	1	the	the	DET
ct-12609	32	2	simplest	simple	ADJ
ct-12609	32	3	explanation	explanation	NOUN
ct-12609	32	4	is	be	AUX
ct-12609	32	5	excessive	excessive	ADJ
ct-12609	32	6	weight	weight	NOUN
ct-12609	32	7	at	at	ADP
ct-12609	32	8	the	the	DET
ct-12609	32	9	hoof	hoof	ADJ
ct-12609	32	10	–	–	PUNCT
ct-12609	32	11	lamellar	lamellar	ADJ
ct-12609	32	12	interface.4	interface.4	NOUN
ct-12609	32	13	the	the	DET
ct-12609	32	14	fact	fact	NOUN
ct-12609	32	15	that	that	SCONJ
ct-12609	32	16	ponies	pony	NOUN
ct-12609	32	17	are	be	AUX
ct-12609	32	18	at	at	ADP
ct-12609	32	19	higher	high	ADJ
ct-12609	32	20	risk	risk	NOUN
ct-12609	32	21	even	even	ADV
ct-12609	32	22	though	though	SCONJ
ct-12609	32	23	they	they	PRON
ct-12609	32	24	bear	bear	VERB
ct-12609	32	25	less	less	ADJ
ct-12609	32	26	weight	weight	NOUN
ct-12609	32	27	,	,	PUNCT
ct-12609	32	28	suggests	suggest	VERB
ct-12609	32	29	the	the	DET
ct-12609	32	30	genetic	genetic	ADJ
ct-12609	32	31	predisposition	predisposition	NOUN
ct-12609	32	32	of	of	ADP
ct-12609	32	33	this	this	DET
ct-12609	32	34	breed	breed	NOUN
ct-12609	32	35	to	to	ADP
ct-12609	32	36	ms	ms	NOUN
ct-12609	32	37	and	and	CCONJ
ct-12609	32	38	ir.2,4,5	ir.2,4,5	VERB
ct-12609	32	39	glucose	glucose	NOUN
ct-12609	32	40	is	be	AUX
ct-12609	32	41	essential	essential	ADJ
ct-12609	32	42	for	for	ADP
ct-12609	32	43	the	the	DET
ct-12609	32	44	health	health	NOUN
ct-12609	32	45	and	and	CCONJ
ct-12609	32	46	strength	strength	NOUN
ct-12609	32	47	of	of	ADP
ct-12609	32	48	the	the	DET
ct-12609	32	49	hoof	hoof	ADJ
ct-12609	32	50	-	-	PUNCT
ct-12609	32	51	lamellar	lamellar	ADJ
ct-12609	32	52	interface	interface	NOUN
ct-12609	32	53	.	.	PUNCT
ct-12609	33	1	ir	ir	PROPN
ct-12609	33	2	creates	create	VERB
ct-12609	33	3	cell	cell	NOUN
ct-12609	33	4	-	-	PUNCT
ct-12609	33	5	glucose	glucose	NOUN
ct-12609	33	6	starvation	starvation	NOUN
ct-12609	33	7	which	which	PRON
ct-12609	33	8	may	may	AUX
ct-12609	33	9	increase	increase	VERB
ct-12609	33	10	the	the	DET
ct-12609	33	11	risk	risk	NOUN
ct-12609	33	12	of	of	ADP
ct-12609	33	13	laminitis	laminitis	NOUN
ct-12609	33	14	more	more	ADJ
ct-12609	33	15	than	than	ADP
ct-12609	33	16	obesity	obesity	NOUN
ct-12609	33	17	per	per	X
ct-12609	33	18	se	se	X
ct-12609	33	19	.	.	PUNCT
ct-12609	34	1	diagnosis	diagnosis	NOUN
ct-12609	34	2	characteristics	characteristic	NOUN
ct-12609	34	3	that	that	PRON
ct-12609	34	4	are	be	AUX
ct-12609	34	5	common	common	ADJ
ct-12609	34	6	in	in	ADP
ct-12609	34	7	horses	horse	NOUN
ct-12609	34	8	with	with	ADP
ct-12609	34	9	ms	ms	PROPN
ct-12609	34	10	or	or	CCONJ
ct-12609	34	11	ir	ir	PROPN
ct-12609	34	12	include	include	VERB
ct-12609	34	13	increased	increase	VERB
ct-12609	34	14	age	age	NOUN
ct-12609	34	15	(	(	PUNCT
ct-12609	34	16	8	8	NUM
ct-12609	34	17	to	to	PART
ct-12609	34	18	20	20	NUM
ct-12609	34	19	years	year	NOUN
ct-12609	34	20	old	old	ADJ
ct-12609	34	21	)	)	PUNCT
ct-12609	34	22	,	,	PUNCT
ct-12609	34	23	obesity	obesity	NOUN
ct-12609	34	24	,	,	PUNCT
ct-12609	34	25	distinctive	distinctive	ADJ
ct-12609	34	26	distribution	distribution	NOUN
ct-12609	34	27	of	of	ADP
ct-12609	34	28	body	body	NOUN
ct-12609	34	29	fat	fat	NOUN
ct-12609	34	30	(	(	PUNCT
ct-12609	34	31	neck	neck	NOUN
ct-12609	34	32	,	,	PUNCT
ct-12609	34	33	shoulders	shoulder	NOUN
ct-12609	34	34	,	,	PUNCT
ct-12609	34	35	rump	rump	NOUN
ct-12609	34	36	)	)	PUNCT
ct-12609	34	37	,	,	PUNCT
ct-12609	34	38	“	"	PUNCT
ct-12609	34	39	easy	easy	ADJ
ct-12609	34	40	keepers	keeper	NOUN
ct-12609	34	41	”	"	PUNCT
ct-12609	34	42	that	that	PRON
ct-12609	34	43	have	have	VERB
ct-12609	34	44	difficulty	difficulty	NOUN
ct-12609	34	45	losing	lose	VERB
ct-12609	34	46	weight	weight	NOUN
ct-12609	34	47	,	,	PUNCT
ct-12609	34	48	a	a	DET
ct-12609	34	49	history	history	NOUN
ct-12609	34	50	,	,	PUNCT
ct-12609	34	51	presence	presence	NOUN
ct-12609	34	52	or	or	CCONJ
ct-12609	34	53	predisposition	predisposition	NOUN
ct-12609	34	54	for	for	ADP
ct-12609	34	55	laminitis	laminitis	NOUN
ct-12609	34	56	,	,	PUNCT
ct-12609	34	57	abnormal	abnormal	ADJ
ct-12609	34	58	estrous	estrous	ADJ
ct-12609	34	59	cycles	cycle	NOUN
ct-12609	34	60	and	and	CCONJ
ct-12609	34	61	decreased	decrease	VERB
ct-12609	34	62	pregnancy	pregnancy	NOUN
ct-12609	34	63	rates	rate	NOUN
ct-12609	34	64	.	.	PUNCT
ct-12609	35	1	resting	rest	VERB
ct-12609	35	2	levels	level	NOUN
ct-12609	35	3	of	of	ADP
ct-12609	35	4	insulin	insulin	NOUN
ct-12609	35	5	are	be	AUX
ct-12609	35	6	good	good	ADJ
ct-12609	35	7	indicators	indicator	NOUN
ct-12609	35	8	of	of	ADP
ct-12609	35	9	ir	ir	PROPN
ct-12609	35	10	since	since	SCONJ
ct-12609	35	11	compensatory	compensatory	ADJ
ct-12609	35	12	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	35	13	is	be	AUX
ct-12609	35	14	a	a	DET
ct-12609	35	15	common	common	ADJ
ct-12609	35	16	finding	finding	NOUN
ct-12609	35	17	.	.	PUNCT
ct-12609	36	1	plasma	plasma	NOUN
ct-12609	36	2	samples	sample	NOUN
ct-12609	36	3	should	should	AUX
ct-12609	36	4	be	be	AUX
ct-12609	36	5	taken	take	VERB
ct-12609	36	6	early	early	ADV
ct-12609	36	7	in	in	ADP
ct-12609	36	8	the	the	DET
ct-12609	36	9	morning	morning	NOUN
ct-12609	36	10	after	after	ADP
ct-12609	36	11	an	an	DET
ct-12609	36	12	overnight	overnight	ADJ
ct-12609	36	13	fast	fast	ADV
ct-12609	36	14	.	.	PUNCT
ct-12609	37	1	horses	horse	NOUN
ct-12609	37	2	should	should	AUX
ct-12609	37	3	be	be	AUX
ct-12609	37	4	removed	remove	VERB
ct-12609	37	5	from	from	ADP
ct-12609	37	6	pasture	pasture	NOUN
ct-12609	37	7	and	and	CCONJ
ct-12609	37	8	only	only	ADV
ct-12609	37	9	fed	feed	VERB
ct-12609	37	10	course	course	NOUN
ct-12609	37	11	roughage	roughage	VERB
ct-12609	37	12	overnight	overnight	ADV
ct-12609	37	13	.	.	PUNCT
ct-12609	38	1	roughage	roughage	NOUN
ct-12609	38	2	should	should	AUX
ct-12609	38	3	be	be	AUX
ct-12609	38	4	available	available	ADJ
ct-12609	38	5	as	as	SCONJ
ct-12609	38	6	some	some	DET
ct-12609	38	7	horses	horse	NOUN
ct-12609	38	8	will	will	AUX
ct-12609	38	9	become	become	VERB
ct-12609	38	10	increasingly	increasingly	ADV
ct-12609	38	11	agitated	agitated	ADJ
ct-12609	38	12	if	if	SCONJ
ct-12609	38	13	no	no	DET
ct-12609	38	14	food	food	NOUN
ct-12609	38	15	is	be	AUX
ct-12609	38	16	available	available	ADJ
ct-12609	38	17	.	.	PUNCT
ct-12609	39	1	resting	rest	VERB
ct-12609	39	2	insulin	insulin	NOUN
ct-12609	39	3	concentrations	concentration	NOUN
ct-12609	39	4	>	>	X
ct-12609	39	5	20	20	NUM
ct-12609	39	6	µu	µu	NUM
ct-12609	39	7	/	/	SYM
ct-12609	39	8	ml	ml	NOUN
ct-12609	39	9	are	be	AUX
ct-12609	39	10	suggestive	suggestive	ADJ
ct-12609	39	11	of	of	ADP
ct-12609	39	12	insulin	insulin	NOUN
ct-12609	39	13	resistance	resistance	NOUN
ct-12609	39	14	and	and	CCONJ
ct-12609	39	15	>	>	X
ct-12609	39	16	30	30	NUM
ct-12609	39	17	µu	µu	NUM
ct-12609	39	18	/	/	SYM
ct-12609	39	19	ml	ml	NOUN
ct-12609	39	20	are	be	AUX
ct-12609	39	21	considered	consider	VERB
ct-12609	39	22	diagnostic.4,6	diagnostic.4,6	PRON
ct-12609	39	23	even	even	ADV
ct-12609	39	24	though	though	SCONJ
ct-12609	39	25	resting	rest	VERB
ct-12609	39	26	levels	level	NOUN
ct-12609	39	27	of	of	ADP
ct-12609	39	28	insulin	insulin	NOUN
ct-12609	39	29	are	be	AUX
ct-12609	39	30	good	good	ADJ
ct-12609	39	31	markers	marker	NOUN
ct-12609	39	32	,	,	PUNCT
ct-12609	39	33	they	they	PRON
ct-12609	39	34	are	be	AUX
ct-12609	39	35	not	not	PART
ct-12609	39	36	helpful	helpful	ADJ
ct-12609	39	37	in	in	ADP
ct-12609	39	38	mild	mild	ADJ
ct-12609	39	39	or	or	CCONJ
ct-12609	39	40	early	early	ADJ
ct-12609	39	41	ir	ir	NOUN
ct-12609	39	42	where	where	SCONJ
ct-12609	39	43	the	the	DET
ct-12609	39	44	rise	rise	NOUN
ct-12609	39	45	of	of	ADP
ct-12609	39	46	insulin	insulin	NOUN
ct-12609	39	47	is	be	AUX
ct-12609	39	48	too	too	ADV
ct-12609	39	49	small	small	ADJ
ct-12609	39	50	to	to	PART
ct-12609	39	51	reach	reach	VERB
ct-12609	39	52	or	or	CCONJ
ct-12609	39	53	exceed	exceed	VERB
ct-12609	39	54	the	the	DET
ct-12609	39	55	reference	reference	NOUN
ct-12609	39	56	value	value	NOUN
ct-12609	39	57	.	.	PUNCT
ct-12609	40	1	reference	reference	NOUN
ct-12609	40	2	values	value	NOUN
ct-12609	40	3	differ	differ	VERB
ct-12609	40	4	among	among	ADP
ct-12609	40	5	laboratories	laboratory	NOUN
ct-12609	40	6	and	and	CCONJ
ct-12609	40	7	should	should	AUX
ct-12609	40	8	be	be	AUX
ct-12609	40	9	taken	take	VERB
ct-12609	40	10	into	into	ADP
ct-12609	40	11	consideration	consideration	NOUN
ct-12609	40	12	when	when	SCONJ
ct-12609	40	13	interpreting	interpreting	NOUN
ct-12609	40	14	results	result	NOUN
ct-12609	40	15	(	(	PUNCT
ct-12609	40	16	insulin	insulin	NOUN
ct-12609	40	17	>	>	SYM
ct-12609	40	18	30	30	NUM
ct-12609	40	19	µu	µu	PROPN
ct-12609	40	20	/	/	SYM
ct-12609	40	21	ml	ml	NOUN
ct-12609	40	22	at	at	ADP
ct-12609	40	23	university	university	PROPN
ct-12609	40	24	of	of	ADP
ct-12609	40	25	tennessee	tennessee	PROPN
ct-12609	40	26	vs.	vs.	X
ct-12609	40	27	>	>	X
ct-12609	40	28	43	43	NUM
ct-12609	40	29	µu	µu	PROPN
ct-12609	40	30	/	/	SYM
ct-12609	40	31	ml	ml	X
ct-12609	40	32	at	at	ADP
ct-12609	40	33	michigan	michigan	PROPN
ct-12609	40	34	state	state	PROPN
ct-12609	40	35	university).6	university).6	PROPN
ct-12609	40	36	if	if	SCONJ
ct-12609	40	37	one	one	PRON
ct-12609	40	38	is	be	AUX
ct-12609	40	39	presented	present	VERB
ct-12609	40	40	a	a	DET
ct-12609	40	41	horse	horse	NOUN
ct-12609	40	42	with	with	ADP
ct-12609	40	43	physical	physical	ADJ
ct-12609	40	44	findings	finding	NOUN
ct-12609	40	45	consistent	consistent	ADJ
ct-12609	40	46	with	with	ADP
ct-12609	40	47	ms	ms	NOUN
ct-12609	40	48	or	or	CCONJ
ct-12609	40	49	cd	cd	PROPN
ct-12609	40	50	that	that	PRON
ct-12609	40	51	has	have	VERB
ct-12609	40	52	a	a	DET
ct-12609	40	53	normal	normal	ADJ
ct-12609	40	54	resting	rest	VERB
ct-12609	40	55	plasma	plasma	NOUN
ct-12609	40	56	insulin	insulin	NOUN
ct-12609	40	57	level	level	NOUN
ct-12609	40	58	,	,	PUNCT
ct-12609	40	59	a	a	DET
ct-12609	40	60	combined	combine	VERB
ct-12609	40	61	glucose	glucose	NOUN
ct-12609	40	62	-	-	PUNCT
ct-12609	40	63	insulin	insulin	NOUN
ct-12609	40	64	test	test	NOUN
ct-12609	40	65	should	should	AUX
ct-12609	40	66	be	be	AUX
ct-12609	40	67	performed.6	performed.6	PROPN
ct-12609	40	68	this	this	DET
ct-12609	40	69	test	test	NOUN
ct-12609	40	70	consists	consist	VERB
ct-12609	40	71	of	of	ADP
ct-12609	40	72	collecting	collect	VERB
ct-12609	40	73	a	a	DET
ct-12609	40	74	baseline	baseline	NOUN
ct-12609	40	75	glucose	glucose	NOUN
ct-12609	40	76	blood	blood	NOUN
ct-12609	40	77	sample	sample	NOUN
ct-12609	40	78	before	before	ADP
ct-12609	40	79	infusing	infuse	VERB
ct-12609	40	80	150	150	NUM
ct-12609	40	81	mg	mg	NUM
ct-12609	40	82	/	/	SYM
ct-12609	40	83	kg	kg	PROPN
ct-12609	40	84	of	of	ADP
ct-12609	40	85	50	50	NUM
ct-12609	40	86	%	%	NOUN
ct-12609	40	87	488	488	NUM
ct-12609	40	88	dextrose	dextrose	NOUN
ct-12609	40	89	solution	solution	NOUN
ct-12609	40	90	.	.	PUNCT
ct-12609	41	1	immediately	immediately	ADV
ct-12609	41	2	after	after	ADP
ct-12609	41	3	the	the	DET
ct-12609	41	4	dextrose	dextrose	NOUN
ct-12609	41	5	infusion	infusion	NOUN
ct-12609	41	6	,	,	PUNCT
ct-12609	41	7	insulin	insulin	NOUN
ct-12609	41	8	is	be	AUX
ct-12609	41	9	administered	administer	VERB
ct-12609	41	10	intravenously	intravenously	ADV
ct-12609	41	11	at	at	ADP
ct-12609	41	12	0.10	0.10	NUM
ct-12609	41	13	u	u	NOUN
ct-12609	41	14	/	/	SYM
ct-12609	41	15	kg	kg	PROPN
ct-12609	41	16	.	.	PUNCT
ct-12609	42	1	serum	serum	NOUN
ct-12609	42	2	samples	sample	NOUN
ct-12609	42	3	are	be	AUX
ct-12609	42	4	collected	collect	VERB
ct-12609	42	5	at	at	ADP
ct-12609	42	6	1	1	NUM
ct-12609	42	7	,	,	PUNCT
ct-12609	42	8	5	5	NUM
ct-12609	42	9	,	,	PUNCT
ct-12609	42	10	25	25	NUM
ct-12609	42	11	,	,	PUNCT
ct-12609	42	12	35	35	NUM
ct-12609	42	13	,	,	PUNCT
ct-12609	42	14	45	45	NUM
ct-12609	42	15	,	,	PUNCT
ct-12609	42	16	60	60	NUM
ct-12609	42	17	,	,	PUNCT
ct-12609	42	18	75	75	NUM
ct-12609	42	19	,	,	PUNCT
ct-12609	42	20	90	90	NUM
ct-12609	42	21	,	,	PUNCT
ct-12609	42	22	105	105	NUM
ct-12609	42	23	,	,	PUNCT
ct-12609	42	24	120	120	NUM
ct-12609	42	25	,	,	PUNCT
ct-12609	42	26	135	135	NUM
ct-12609	42	27	and	and	CCONJ
ct-12609	42	28	150	150	NUM
ct-12609	42	29	min	min	NOUN
ct-12609	42	30	.	.	PROPN
ct-12609	43	1	however	however	ADV
ct-12609	43	2	for	for	ADP
ct-12609	43	3	practical	practical	ADJ
ct-12609	43	4	purposes	purpose	NOUN
ct-12609	43	5	,	,	PUNCT
ct-12609	43	6	the	the	DET
ct-12609	43	7	test	test	NOUN
ct-12609	43	8	can	can	AUX
ct-12609	43	9	be	be	AUX
ct-12609	43	10	limited	limit	VERB
ct-12609	43	11	to	to	ADP
ct-12609	43	12	60	60	NUM
ct-12609	43	13	minutes	minute	NOUN
ct-12609	43	14	.	.	PUNCT
ct-12609	44	1	a	a	DET
ct-12609	44	2	horse	horse	NOUN
ct-12609	44	3	is	be	AUX
ct-12609	44	4	considered	consider	VERB
ct-12609	44	5	to	to	PART
ct-12609	44	6	have	have	VERB
ct-12609	44	7	insulin	insulin	NOUN
ct-12609	44	8	resistance	resistance	NOUN
ct-12609	44	9	if	if	SCONJ
ct-12609	44	10	blood	blood	NOUN
ct-12609	44	11	glucose	glucose	NOUN
ct-12609	44	12	levels	level	NOUN
ct-12609	44	13	remain	remain	VERB
ct-12609	44	14	above	above	ADP
ct-12609	44	15	baseline	baseline	NOUN
ct-12609	44	16	for	for	ADP
ct-12609	44	17	more	more	ADJ
ct-12609	44	18	than	than	ADP
ct-12609	44	19	45	45	NUM
ct-12609	44	20	min.6	min.6	NOUN
ct-12609	44	21	stress	stress	NOUN
ct-12609	44	22	should	should	AUX
ct-12609	44	23	be	be	AUX
ct-12609	44	24	avoided	avoid	VERB
ct-12609	44	25	during	during	ADP
ct-12609	44	26	the	the	DET
ct-12609	44	27	test	test	NOUN
ct-12609	44	28	since	since	SCONJ
ct-12609	44	29	it	it	PRON
ct-12609	44	30	can	can	AUX
ct-12609	44	31	cause	cause	VERB
ct-12609	44	32	transient	transient	ADJ
ct-12609	44	33	ir	ir	PROPN
ct-12609	44	34	.	.	PUNCT
ct-12609	44	35	horses	horse	NOUN
ct-12609	44	36	should	should	AUX
ct-12609	44	37	be	be	AUX
ct-12609	44	38	kept	keep	VERB
ct-12609	44	39	quiet	quiet	ADJ
ct-12609	44	40	,	,	PUNCT
ct-12609	44	41	allowed	allow	VERB
ct-12609	44	42	to	to	PART
ct-12609	44	43	graze	graze	VERB
ct-12609	44	44	and	and	CCONJ
ct-12609	44	45	the	the	DET
ct-12609	44	46	jugular	jugular	ADJ
ct-12609	44	47	catheter	catheter	NOUN
ct-12609	44	48	should	should	AUX
ct-12609	44	49	be	be	AUX
ct-12609	44	50	placed	place	VERB
ct-12609	44	51	the	the	DET
ct-12609	44	52	night	night	NOUN
ct-12609	44	53	before	before	ADP
ct-12609	44	54	for	for	ADP
ct-12609	44	55	blood	blood	NOUN
ct-12609	44	56	collection	collection	NOUN
ct-12609	44	57	.	.	PUNCT
ct-12609	45	1	metabolic	metabolic	NOUN
ct-12609	45	2	syndrome	syndrome	PROPN
ct-12609	45	3	and	and	CCONJ
ct-12609	45	4	cd	cd	PROPN
ct-12609	45	5	share	share	VERB
ct-12609	45	6	a	a	DET
ct-12609	45	7	number	number	NOUN
ct-12609	45	8	of	of	ADP
ct-12609	45	9	clinical	clinical	ADJ
ct-12609	45	10	signs	sign	NOUN
ct-12609	45	11	including	include	VERB
ct-12609	45	12	abnormal	abnormal	ADJ
ct-12609	45	13	distribution	distribution	NOUN
ct-12609	45	14	of	of	ADP
ct-12609	45	15	fat	fat	ADJ
ct-12609	45	16	,	,	PUNCT
ct-12609	45	17	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	45	18	and	and	CCONJ
ct-12609	45	19	insulin	insulin	NOUN
ct-12609	45	20	resistance	resistance	NOUN
ct-12609	45	21	,	,	PUNCT
ct-12609	45	22	predisposition	predisposition	NOUN
ct-12609	45	23	to	to	ADP
ct-12609	45	24	laminitis	laminitis	NOUN
ct-12609	45	25	and	and	CCONJ
ct-12609	45	26	infertility	infertility	NOUN
ct-12609	45	27	.	.	PUNCT
ct-12609	46	1	cushing	cushing	NOUN
ct-12609	46	2	’s	’s	PART
ct-12609	46	3	disease	disease	NOUN
ct-12609	46	4	can	can	AUX
ct-12609	46	5	be	be	AUX
ct-12609	46	6	differentiated	differentiate	VERB
ct-12609	46	7	from	from	ADP
ct-12609	46	8	ms	ms	NOUN
ct-12609	46	9	by	by	ADP
ct-12609	46	10	performing	perform	VERB
ct-12609	46	11	a	a	DET
ct-12609	46	12	dexamethasone	dexamethasone	NOUN
ct-12609	46	13	suppression	suppression	NOUN
ct-12609	46	14	test	test	NOUN
ct-12609	46	15	(	(	PUNCT
ct-12609	46	16	dst	dst	NOUN
ct-12609	46	17	;	;	PUNCT
ct-12609	46	18	see	see	VERB
ct-12609	46	19	ppid	ppid	NOUN
ct-12609	46	20	)	)	PUNCT
ct-12609	46	21	,	,	PUNCT
ct-12609	46	22	as	as	SCONJ
ct-12609	46	23	this	this	DET
ct-12609	46	24	test	test	NOUN
ct-12609	46	25	will	will	AUX
ct-12609	46	26	be	be	AUX
ct-12609	46	27	positive	positive	ADJ
ct-12609	46	28	only	only	ADV
ct-12609	46	29	for	for	ADP
ct-12609	46	30	ppid	ppid	NOUN
ct-12609	46	31	.	.	PUNCT
ct-12609	47	1	indeed	indeed	ADV
ct-12609	47	2	,	,	PUNCT
ct-12609	47	3	ms	ms	PROPN
ct-12609	47	4	has	have	AUX
ct-12609	47	5	been	be	AUX
ct-12609	47	6	described	describe	VERB
ct-12609	47	7	as	as	ADP
ct-12609	47	8	the	the	DET
ct-12609	47	9	presence	presence	NOUN
ct-12609	47	10	of	of	ADP
ct-12609	47	11	insulin	insulin	NOUN
ct-12609	47	12	resistance	resistance	NOUN
ct-12609	47	13	without	without	ADP
ct-12609	47	14	detectable	detectable	ADJ
ct-12609	47	15	presence	presence	NOUN
ct-12609	47	16	of	of	ADP
ct-12609	47	17	ppid.7	ppid.7	ADJ
ct-12609	47	18	treatment	treatment	NOUN
ct-12609	47	19	treatment	treatment	NOUN
ct-12609	47	20	is	be	AUX
ct-12609	47	21	directed	direct	VERB
ct-12609	47	22	at	at	ADP
ct-12609	47	23	lowering	lower	VERB
ct-12609	47	24	body	body	NOUN
ct-12609	47	25	fat	fat	NOUN
ct-12609	47	26	and	and	CCONJ
ct-12609	47	27	consequently	consequently	ADV
ct-12609	47	28	insulin	insulin	NOUN
ct-12609	47	29	levels	level	NOUN
ct-12609	47	30	to	to	ADP
ct-12609	47	31	<	<	X
ct-12609	47	32	30	30	NUM
ct-12609	47	33	µu	µu	NUM
ct-12609	47	34	/	/	SYM
ct-12609	47	35	ml	ml	NOUN
ct-12609	47	36	.	.	PUNCT
ct-12609	48	1	horses	horse	NOUN
ct-12609	48	2	should	should	AUX
ct-12609	48	3	be	be	AUX
ct-12609	48	4	placed	place	VERB
ct-12609	48	5	on	on	ADP
ct-12609	48	6	a	a	DET
ct-12609	48	7	low	low	ADJ
ct-12609	48	8	carbohydrate	carbohydrate	NOUN
ct-12609	48	9	diet	diet	NOUN
ct-12609	48	10	to	to	PART
ct-12609	48	11	reduce	reduce	VERB
ct-12609	48	12	caloric	caloric	NOUN
ct-12609	48	13	intake	intake	NOUN
ct-12609	48	14	and	and	CCONJ
ct-12609	48	15	partake	partake	VERB
ct-12609	48	16	in	in	ADP
ct-12609	48	17	a	a	DET
ct-12609	48	18	consistent	consistent	ADJ
ct-12609	48	19	exercise	exercise	NOUN
ct-12609	48	20	program	program	NOUN
ct-12609	48	21	to	to	PART
ct-12609	48	22	increase	increase	VERB
ct-12609	48	23	energy	energy	NOUN
ct-12609	48	24	outflow	outflow	NOUN
ct-12609	48	25	and	and	CCONJ
ct-12609	48	26	glucose	glucose	NOUN
ct-12609	48	27	uptake	uptake	ADJ
ct-12609	48	28	.	.	PUNCT
ct-12609	49	1	grain	grain	NOUN
ct-12609	49	2	should	should	AUX
ct-12609	49	3	be	be	AUX
ct-12609	49	4	removed	remove	VERB
ct-12609	49	5	from	from	ADP
ct-12609	49	6	the	the	DET
ct-12609	49	7	diet	diet	NOUN
ct-12609	49	8	(	(	PUNCT
ct-12609	49	9	alone	alone	ADV
ct-12609	49	10	or	or	CCONJ
ct-12609	49	11	mixed	mix	VERB
ct-12609	49	12	with	with	ADP
ct-12609	49	13	molasses	molasse	NOUN
ct-12609	49	14	)	)	PUNCT
ct-12609	49	15	and	and	CCONJ
ct-12609	49	16	access	access	NOUN
ct-12609	49	17	to	to	ADP
ct-12609	49	18	pasture	pasture	NOUN
ct-12609	49	19	should	should	AUX
ct-12609	49	20	be	be	AUX
ct-12609	49	21	limited	limit	VERB
ct-12609	49	22	.	.	PUNCT
ct-12609	50	1	medical	medical	ADJ
ct-12609	50	2	treatment	treatment	NOUN
ct-12609	50	3	with	with	ADP
ct-12609	50	4	levothyroxine	levothyroxine	NOUN
ct-12609	50	5	sodium	sodium	NOUN
ct-12609	50	6	(	(	PUNCT
ct-12609	50	7	thyro	thyro	NOUN
ct-12609	50	8	l	l	NOUN
ct-12609	50	9	;	;	PUNCT
ct-12609	50	10	vet	vet	NOUN
ct-12609	50	11	-	-	PUNCT
ct-12609	50	12	a	a	DET
ct-12609	50	13	-	-	PUNCT
ct-12609	50	14	mix	mix	NOUN
ct-12609	50	15	,	,	PUNCT
ct-12609	50	16	shenandoah	shenandoah	NOUN
ct-12609	50	17	,	,	PUNCT
ct-12609	50	18	ia	ia	PROPN
ct-12609	50	19	,	,	PUNCT
ct-12609	50	20	usa	usa	PROPN
ct-12609	50	21	)	)	PUNCT
ct-12609	50	22	is	be	AUX
ct-12609	50	23	warranted	warrant	VERB
ct-12609	50	24	if	if	SCONJ
ct-12609	50	25	weight	weight	NOUN
ct-12609	50	26	loss	loss	NOUN
ct-12609	50	27	occurs	occur	VERB
ct-12609	50	28	too	too	ADV
ct-12609	50	29	slowly	slowly	ADV
ct-12609	50	30	or	or	CCONJ
ct-12609	50	31	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	50	32	persists	persist	NOUN
ct-12609	50	33	after	after	ADP
ct-12609	50	34	reaching	reach	VERB
ct-12609	50	35	the	the	DET
ct-12609	50	36	desirable	desirable	ADJ
ct-12609	50	37	body	body	NOUN
ct-12609	50	38	weight.4	weight.4	PRON
ct-12609	50	39	levothyroxine	levothyroxine	NOUN
ct-12609	50	40	sodium	sodium	NOUN
ct-12609	50	41	is	be	AUX
ct-12609	50	42	administered	administer	VERB
ct-12609	50	43	at	at	ADP
ct-12609	50	44	a	a	DET
ct-12609	50	45	dose	dose	NOUN
ct-12609	50	46	of	of	ADP
ct-12609	50	47	48	48	NUM
ct-12609	50	48	mg	mg	PROPN
ct-12609	50	49	/	/	SYM
ct-12609	50	50	day	day	NOUN
ct-12609	50	51	po	po	NOUN
ct-12609	50	52	for	for	ADP
ct-12609	50	53	3	3	NUM
ct-12609	50	54	to	to	PART
ct-12609	50	55	6	6	NUM
ct-12609	50	56	months	month	NOUN
ct-12609	50	57	to	to	PART
ct-12609	50	58	accelerate	accelerate	VERB
ct-12609	50	59	weight	weight	NOUN
ct-12609	50	60	loss	loss	NOUN
ct-12609	50	61	in	in	ADP
ct-12609	50	62	horses	horse	NOUN
ct-12609	50	63	,	,	PUNCT
ct-12609	50	64	especially	especially	ADV
ct-12609	50	65	those	those	PRON
ct-12609	50	66	which	which	PRON
ct-12609	50	67	can	can	AUX
ct-12609	50	68	not	not	PART
ct-12609	50	69	exercise	exercise	VERB
ct-12609	50	70	due	due	ADP
ct-12609	50	71	to	to	ADP
ct-12609	50	72	laminitis	laminitis	NOUN
ct-12609	50	73	.	.	PUNCT
ct-12609	51	1	persistent	persistent	ADJ
ct-12609	51	2	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	51	3	/	/	SYM
ct-12609	51	4	hyperglycemia	hyperglycemia	NOUN
ct-12609	51	5	is	be	AUX
ct-12609	51	6	treated	treat	VERB
ct-12609	51	7	with	with	ADP
ct-12609	51	8	a	a	DET
ct-12609	51	9	combination	combination	NOUN
ct-12609	51	10	of	of	ADP
ct-12609	51	11	levothyroxine	levothyroxine	PROPN
ct-12609	51	12	sodium	sodium	NOUN
ct-12609	51	13	(	(	PUNCT
ct-12609	51	14	24	24	NUM
ct-12609	51	15	mg	mg	NUM
ct-12609	51	16	/	/	SYM
ct-12609	51	17	day	day	NOUN
ct-12609	51	18	po	po	NOUN
ct-12609	51	19	)	)	PUNCT
ct-12609	51	20	and	and	CCONJ
ct-12609	51	21	a	a	DET
ct-12609	51	22	biguanide	biguanide	NOUN
ct-12609	51	23	(	(	PUNCT
ct-12609	51	24	metformin	metformin	NOUN
ct-12609	51	25	;	;	PUNCT
ct-12609	51	26	15	15	NUM
ct-12609	51	27	mg	mg	NUM
ct-12609	51	28	/	/	SYM
ct-12609	51	29	kg	kg	PROPN
ct-12609	51	30	po	po	NOUN
ct-12609	51	31	bid	bid	NOUN
ct-12609	51	32	)	)	PUNCT
ct-12609	51	33	.	.	PUNCT
ct-12609	52	1	the	the	DET
ct-12609	52	2	489	489	NUM
ct-12609	52	3	mechanism	mechanism	NOUN
ct-12609	52	4	of	of	ADP
ct-12609	52	5	action	action	NOUN
ct-12609	52	6	is	be	AUX
ct-12609	52	7	not	not	PART
ct-12609	52	8	known	know	VERB
ct-12609	52	9	but	but	CCONJ
ct-12609	52	10	it	it	PRON
ct-12609	52	11	appears	appear	VERB
ct-12609	52	12	to	to	PART
ct-12609	52	13	inhibit	inhibit	VERB
ct-12609	52	14	gluconeogenesis	gluconeogenesis	NOUN
ct-12609	52	15	and	and	CCONJ
ct-12609	52	16	increases	increase	VERB
ct-12609	52	17	glucose	glucose	VERB
ct-12609	52	18	uptake.4	uptake.4	ADV
ct-12609	52	19	its	its	PRON
ct-12609	52	20	safety	safety	NOUN
ct-12609	52	21	in	in	ADP
ct-12609	52	22	the	the	DET
ct-12609	52	23	horse	horse	NOUN
ct-12609	52	24	has	have	AUX
ct-12609	52	25	not	not	PART
ct-12609	52	26	been	be	AUX
ct-12609	52	27	established	establish	VERB
ct-12609	52	28	.	.	PUNCT
ct-12609	53	1	in	in	ADP
ct-12609	53	2	addition	addition	NOUN
ct-12609	53	3	,	,	PUNCT
ct-12609	53	4	administration	administration	NOUN
ct-12609	53	5	of	of	ADP
ct-12609	53	6	chromium	chromium	NOUN
ct-12609	53	7	at	at	ADP
ct-12609	53	8	a	a	DET
ct-12609	53	9	dose	dose	NOUN
ct-12609	53	10	of	of	ADP
ct-12609	53	11	5	5	NUM
ct-12609	53	12	to	to	PART
ct-12609	53	13	25	25	NUM
ct-12609	53	14	mg	mg	NOUN
ct-12609	53	15	/	/	SYM
ct-12609	53	16	day	day	NOUN
ct-12609	53	17	may	may	AUX
ct-12609	53	18	improve	improve	VERB
ct-12609	53	19	insulin	insulin	NOUN
ct-12609	53	20	efficacy	efficacy	NOUN
ct-12609	53	21	in	in	ADP
ct-12609	53	22	transporting	transport	VERB
ct-12609	53	23	glucose	glucose	NOUN
ct-12609	53	24	into	into	ADP
ct-12609	53	25	the	the	DET
ct-12609	53	26	cells.4,7	cells.4,7	PROPN
ct-12609	53	27	cushing	cushing	NOUN
ct-12609	53	28	’s	’s	PART
ct-12609	53	29	disease	disease	NOUN
ct-12609	53	30	or	or	CCONJ
ct-12609	53	31	pituitary	pituitary	ADJ
ct-12609	53	32	pars	par	NOUN
ct-12609	53	33	intermedia	intermedia	PROPN
ct-12609	53	34	dysfunction	dysfunction	PROPN
ct-12609	53	35	cushing	cushing	PROPN
ct-12609	53	36	’s	’s	PART
ct-12609	53	37	disease	disease	NOUN
ct-12609	53	38	or	or	CCONJ
ct-12609	53	39	ppid	ppid	NOUN
ct-12609	53	40	is	be	AUX
ct-12609	53	41	a	a	DET
ct-12609	53	42	relatively	relatively	ADV
ct-12609	53	43	prevalent	prevalent	ADJ
ct-12609	53	44	condition	condition	NOUN
ct-12609	53	45	in	in	ADP
ct-12609	53	46	horses	horse	NOUN
ct-12609	53	47	due	due	ADP
ct-12609	53	48	to	to	ADP
ct-12609	53	49	an	an	DET
ct-12609	53	50	increase	increase	NOUN
ct-12609	53	51	in	in	ADP
ct-12609	53	52	the	the	DET
ct-12609	53	53	geriatric	geriatric	ADJ
ct-12609	53	54	population.8,9	population.8,9	PROPN
ct-12609	53	55	onset	onset	NOUN
ct-12609	53	56	of	of	ADP
ct-12609	53	57	clinical	clinical	ADJ
ct-12609	53	58	signs	sign	NOUN
ct-12609	53	59	usually	usually	ADV
ct-12609	53	60	occurs	occur	VERB
ct-12609	53	61	around	around	ADP
ct-12609	53	62	18	18	NUM
ct-12609	53	63	to	to	PART
ct-12609	53	64	23	23	NUM
ct-12609	53	65	years	year	NOUN
ct-12609	53	66	of	of	ADP
ct-12609	53	67	age	age	NOUN
ct-12609	53	68	but	but	CCONJ
ct-12609	53	69	horses	horse	NOUN
ct-12609	53	70	as	as	ADV
ct-12609	53	71	young	young	ADJ
ct-12609	53	72	as	as	ADP
ct-12609	53	73	7	7	NUM
ct-12609	53	74	years	year	NOUN
ct-12609	53	75	have	have	AUX
ct-12609	53	76	been	be	AUX
ct-12609	53	77	affected	affect	VERB
ct-12609	53	78	.	.	PUNCT
ct-12609	54	1	there	there	PRON
ct-12609	54	2	is	be	VERB
ct-12609	54	3	no	no	DET
ct-12609	54	4	sex	sex	NOUN
ct-12609	54	5	predisposition	predisposition	NOUN
ct-12609	54	6	and	and	CCONJ
ct-12609	54	7	all	all	DET
ct-12609	54	8	breeds	breed	NOUN
ct-12609	54	9	can	can	AUX
ct-12609	54	10	be	be	AUX
ct-12609	54	11	affected	affect	VERB
ct-12609	54	12	.	.	PUNCT
ct-12609	55	1	ponies	pony	NOUN
ct-12609	55	2	and	and	CCONJ
ct-12609	55	3	morgan	morgan	PROPN
ct-12609	55	4	horses	horse	NOUN
ct-12609	55	5	appear	appear	VERB
ct-12609	55	6	to	to	PART
ct-12609	55	7	be	be	AUX
ct-12609	55	8	at	at	ADP
ct-12609	55	9	a	a	DET
ct-12609	55	10	higher	high	ADJ
ct-12609	55	11	risk.10	risk.10	NOUN
ct-12609	55	12	first	first	ADV
ct-12609	55	13	described	describe	VERB
ct-12609	55	14	by	by	ADP
ct-12609	55	15	pallaske	pallaske	PROPN
ct-12609	55	16	75	75	NUM
ct-12609	55	17	years	year	NOUN
ct-12609	55	18	ago	ago	ADV
ct-12609	55	19	,	,	PUNCT
ct-12609	55	20	this	this	DET
ct-12609	55	21	syndrome	syndrome	NOUN
ct-12609	55	22	is	be	AUX
ct-12609	55	23	characterized	characterize	VERB
ct-12609	55	24	by	by	ADP
ct-12609	55	25	adrenocortical	adrenocortical	ADJ
ct-12609	55	26	hyperplasia	hyperplasia	NOUN
ct-12609	55	27	and	and	CCONJ
ct-12609	55	28	excessive	excessive	ADJ
ct-12609	55	29	glucocorticoid	glucocorticoid	NOUN
ct-12609	55	30	,	,	PUNCT
ct-12609	55	31	mineralocorticoid	mineralocorticoid	NOUN
ct-12609	55	32	and	and	CCONJ
ct-12609	55	33	androgenic	androgenic	ADJ
ct-12609	55	34	steroid	steroid	NOUN
ct-12609	55	35	secretion	secretion	NOUN
ct-12609	55	36	in	in	ADP
ct-12609	55	37	response	response	NOUN
ct-12609	55	38	to	to	ADP
ct-12609	55	39	a	a	DET
ct-12609	55	40	surplus	surplus	ADJ
ct-12609	55	41	release	release	NOUN
ct-12609	55	42	of	of	ADP
ct-12609	55	43	adrenocorticotrophic	adrenocorticotrophic	ADJ
ct-12609	55	44	hormone	hormone	NOUN
ct-12609	55	45	(	(	PUNCT
ct-12609	55	46	acth).11	acth).11	PROPN
ct-12609	55	47	in	in	ADP
ct-12609	55	48	the	the	DET
ct-12609	55	49	horse	horse	NOUN
ct-12609	55	50	,	,	PUNCT
ct-12609	55	51	there	there	PRON
ct-12609	55	52	is	be	VERB
ct-12609	55	53	a	a	DET
ct-12609	55	54	hypothalamic	hypothalamic	ADJ
ct-12609	55	55	or	or	CCONJ
ct-12609	55	56	pituitary	pituitary	ADJ
ct-12609	55	57	-	-	PUNCT
ct-12609	55	58	dependant	dependant	ADJ
ct-12609	55	59	hyperadrenocorticism	hyperadrenocorticism	NOUN
ct-12609	55	60	.	.	PUNCT
ct-12609	56	1	the	the	DET
ct-12609	56	2	presence	presence	NOUN
ct-12609	56	3	of	of	ADP
ct-12609	56	4	a	a	DET
ct-12609	56	5	possible	possible	ADJ
ct-12609	56	6	benign	benign	ADJ
ct-12609	56	7	adenoma	adenoma	NOUN
ct-12609	56	8	in	in	ADP
ct-12609	56	9	the	the	DET
ct-12609	56	10	pituitary	pituitary	ADJ
ct-12609	56	11	gland	gland	NOUN
ct-12609	56	12	or	or	CCONJ
ct-12609	56	13	the	the	DET
ct-12609	56	14	degeneration	degeneration	NOUN
ct-12609	56	15	of	of	ADP
ct-12609	56	16	dopaminergic	dopaminergic	ADJ
ct-12609	56	17	neurons	neuron	NOUN
ct-12609	56	18	at	at	ADP
ct-12609	56	19	the	the	DET
ct-12609	56	20	hypothalamic	hypothalamic	ADJ
ct-12609	56	21	level	level	NOUN
ct-12609	56	22	had	have	AUX
ct-12609	56	23	been	be	AUX
ct-12609	56	24	held	hold	VERB
ct-12609	56	25	responsible.6,9,12	responsible.6,9,12	ADJ
ct-12609	56	26	pathophysiology	pathophysiology	NOUN
ct-12609	56	27	.	.	PUNCT
ct-12609	57	1	the	the	DET
ct-12609	57	2	hypothalamus	hypothalamus	PROPN
ct-12609	57	3	controls	control	VERB
ct-12609	57	4	secretion	secretion	NOUN
ct-12609	57	5	of	of	ADP
ct-12609	57	6	acth	acth	NOUN
ct-12609	57	7	by	by	ADP
ct-12609	57	8	the	the	DET
ct-12609	57	9	anterior	anterior	ADJ
ct-12609	57	10	pituitary	pituitary	NOUN
ct-12609	57	11	through	through	ADP
ct-12609	57	12	the	the	DET
ct-12609	57	13	release	release	NOUN
ct-12609	57	14	of	of	ADP
ct-12609	57	15	corticotrophin	corticotrophin	NOUN
ct-12609	57	16	releasing	release	VERB
ct-12609	57	17	hormone	hormone	NOUN
ct-12609	57	18	(	(	PUNCT
ct-12609	57	19	crh	crh	PROPN
ct-12609	57	20	)	)	PUNCT
ct-12609	57	21	.	.	PUNCT
ct-12609	58	1	neurons	neuron	NOUN
ct-12609	58	2	secreting	secrete	VERB
ct-12609	58	3	crh	crh	PROPN
ct-12609	58	4	are	be	AUX
ct-12609	58	5	located	locate	VERB
ct-12609	58	6	in	in	ADP
ct-12609	58	7	the	the	DET
ct-12609	58	8	anterior	anterior	ADJ
ct-12609	58	9	portion	portion	NOUN
ct-12609	58	10	of	of	ADP
ct-12609	58	11	the	the	DET
ct-12609	58	12	paraventricular	paraventricular	ADJ
ct-12609	58	13	nuclei	nucleus	NOUN
ct-12609	58	14	and	and	CCONJ
ct-12609	58	15	their	their	PRON
ct-12609	58	16	axons	axon	NOUN
ct-12609	58	17	terminate	terminate	VERB
ct-12609	58	18	in	in	ADP
ct-12609	58	19	the	the	DET
ct-12609	58	20	pituitary	pituitary	ADJ
ct-12609	58	21	median	median	ADJ
ct-12609	58	22	eminence	eminence	NOUN
ct-12609	58	23	.	.	PUNCT
ct-12609	59	1	corticotrophin	corticotrophin	PROPN
ct-12609	59	2	releasing	release	VERB
ct-12609	59	3	hormone	hormone	NOUN
ct-12609	59	4	stimulates	stimulate	NOUN
ct-12609	59	5	secretion	secretion	NOUN
ct-12609	59	6	of	of	ADP
ct-12609	59	7	acth	acth	NOUN
ct-12609	59	8	,	,	PUNCT
ct-12609	59	9	beta	beta	NOUN
ct-12609	59	10	-	-	PUNCT
ct-12609	59	11	lipotropin	lipotropin	NOUN
ct-12609	59	12	(	(	PUNCT
ct-12609	59	13	ß	ß	NOUN
ct-12609	59	14	-	-	PUNCT
ct-12609	59	15	lph	lph	NOUN
ct-12609	59	16	)	)	PUNCT
ct-12609	59	17	and	and	CCONJ
ct-12609	59	18	ß	ß	NOUN
ct-12609	59	19	-	-	NOUN
ct-12609	59	20	endorphins	endorphin	NOUN
ct-12609	59	21	.	.	PUNCT
ct-12609	60	1	all	all	DET
ct-12609	60	2	three	three	NUM
ct-12609	60	3	originate	originate	VERB
ct-12609	60	4	from	from	ADP
ct-12609	60	5	the	the	DET
ct-12609	60	6	same	same	ADJ
ct-12609	60	7	precursor	precursor	NOUN
ct-12609	60	8	called	call	VERB
ct-12609	60	9	pro	pro	ADJ
ct-12609	60	10	-	-	ADJ
ct-12609	60	11	opiomelanocortin	opiomelanocortin	ADJ
ct-12609	60	12	(	(	PUNCT
ct-12609	60	13	pomc),9,11	pomc),9,11	NOUN
ct-12609	60	14	and	and	CCONJ
ct-12609	60	15	all	all	PRON
ct-12609	60	16	have	have	VERB
ct-12609	60	17	the	the	DET
ct-12609	60	18	same	same	ADJ
ct-12609	60	19	secretory	secretory	ADJ
ct-12609	60	20	dynamics	dynamic	NOUN
ct-12609	60	21	,	,	PUNCT
ct-12609	60	22	that	that	PRON
ct-12609	60	23	is	be	AUX
ct-12609	60	24	release	release	NOUN
ct-12609	60	25	is	be	AUX
ct-12609	60	26	increased	increase	VERB
ct-12609	60	27	in	in	ADP
ct-12609	60	28	response	response	NOUN
ct-12609	60	29	to	to	ADP
ct-12609	60	30	stress	stress	NOUN
ct-12609	60	31	and	and	CCONJ
ct-12609	60	32	hypoglycemia	hypoglycemia	NOUN
ct-12609	60	33	and	and	CCONJ
ct-12609	60	34	decreased	decrease	VERB
ct-12609	60	35	in	in	ADP
ct-12609	60	36	response	response	NOUN
ct-12609	60	37	to	to	ADP
ct-12609	60	38	glucocorticoids	glucocorticoid	NOUN
ct-12609	60	39	.	.	PUNCT
ct-12609	61	1	490	490	NUM
ct-12609	61	2	negative	negative	ADJ
ct-12609	61	3	feedback	feedback	NOUN
ct-12609	61	4	inhibition	inhibition	NOUN
ct-12609	61	5	of	of	ADP
ct-12609	61	6	acth	acth	NOUN
ct-12609	61	7	by	by	ADP
ct-12609	61	8	glucocorticoids	glucocorticoid	NOUN
ct-12609	61	9	is	be	AUX
ct-12609	61	10	absent	absent	ADJ
ct-12609	61	11	in	in	ADP
ct-12609	61	12	ppid	ppid	NOUN
ct-12609	61	13	.	.	PUNCT
ct-12609	62	1	therefore	therefore	ADV
ct-12609	62	2	,	,	PUNCT
ct-12609	62	3	acth	acth	NOUN
ct-12609	62	4	and	and	CCONJ
ct-12609	62	5	pomc	pomc	NOUN
ct-12609	62	6	related	relate	VERB
ct-12609	62	7	hormones	hormone	NOUN
ct-12609	62	8	persist	persist	VERB
ct-12609	62	9	despite	despite	SCONJ
ct-12609	62	10	cortisol	cortisol	NOUN
ct-12609	62	11	elevation.12	elevation.12	PROPN
ct-12609	62	12	chronic	chronic	ADJ
ct-12609	62	13	exposure	exposure	NOUN
ct-12609	62	14	to	to	ADP
ct-12609	62	15	excessive	excessive	ADJ
ct-12609	62	16	glucocorticoids	glucocorticoid	NOUN
ct-12609	62	17	results	result	NOUN
ct-12609	62	18	in	in	ADP
ct-12609	62	19	a	a	DET
ct-12609	62	20	variety	variety	NOUN
ct-12609	62	21	of	of	ADP
ct-12609	62	22	physical	physical	ADJ
ct-12609	62	23	and	and	CCONJ
ct-12609	62	24	clinical	clinical	ADJ
ct-12609	62	25	abnormalities	abnormality	NOUN
ct-12609	62	26	.	.	PUNCT
ct-12609	63	1	the	the	DET
ct-12609	63	2	most	most	ADV
ct-12609	63	3	characteristic	characteristic	ADJ
ct-12609	63	4	clinical	clinical	ADJ
ct-12609	63	5	sign	sign	NOUN
ct-12609	63	6	is	be	AUX
ct-12609	63	7	hirsutism	hirsutism	NOUN
ct-12609	63	8	(	(	PUNCT
ct-12609	63	9	47	47	NUM
ct-12609	63	10	to	to	PART
ct-12609	63	11	100	100	NUM
ct-12609	63	12	%	%	NOUN
ct-12609	63	13	of	of	ADP
ct-12609	63	14	affected	affect	VERB
ct-12609	63	15	horses	horse	NOUN
ct-12609	63	16	)	)	PUNCT
ct-12609	63	17	and	and	CCONJ
ct-12609	63	18	the	the	DET
ct-12609	63	19	inability	inability	NOUN
ct-12609	63	20	to	to	PART
ct-12609	63	21	shed	shed	VERB
ct-12609	63	22	the	the	DET
ct-12609	63	23	winter	winter	NOUN
ct-12609	63	24	coat	coat	NOUN
ct-12609	63	25	.	.	PUNCT
ct-12609	64	1	it	it	PRON
ct-12609	64	2	is	be	AUX
ct-12609	64	3	suggested	suggest	VERB
ct-12609	64	4	that	that	SCONJ
ct-12609	64	5	hirsutism	hirsutism	NOUN
ct-12609	64	6	results	result	VERB
ct-12609	64	7	from	from	ADP
ct-12609	64	8	increased	increase	VERB
ct-12609	64	9	melanocyte	melanocyte	NOUN
ct-12609	64	10	-	-	PUNCT
ct-12609	64	11	stimulating	stimulate	VERB
ct-12609	64	12	hormone	hormone	NOUN
ct-12609	64	13	(	(	PUNCT
ct-12609	64	14	msh	msh	PROPN
ct-12609	64	15	)	)	PUNCT
ct-12609	64	16	released	release	VERB
ct-12609	64	17	from	from	ADP
ct-12609	64	18	the	the	DET
ct-12609	64	19	pars	par	NOUN
ct-12609	64	20	intermedia	intermedia	PROPN
ct-12609	64	21	or	or	CCONJ
ct-12609	64	22	increased	increase	VERB
ct-12609	64	23	production	production	NOUN
ct-12609	64	24	of	of	ADP
ct-12609	64	25	androgens	androgen	NOUN
ct-12609	64	26	by	by	ADP
ct-12609	64	27	the	the	DET
ct-12609	64	28	adrenal	adrenal	ADJ
ct-12609	64	29	cortex	cortex	NOUN
ct-12609	64	30	.	.	PUNCT
ct-12609	65	1	in	in	ADP
ct-12609	65	2	women	woman	NOUN
ct-12609	65	3	,	,	PUNCT
ct-12609	65	4	hirsutism	hirsutism	PROPN
ct-12609	65	5	has	have	AUX
ct-12609	65	6	been	be	AUX
ct-12609	65	7	associated	associate	VERB
ct-12609	65	8	with	with	ADP
ct-12609	65	9	clinical	clinical	ADJ
ct-12609	65	10	hyper	hyper	NOUN
ct-12609	65	11	-	-	NOUN
ct-12609	65	12	androgenism.13	androgenism.13	NOUN
ct-12609	65	13	in	in	ADP
ct-12609	65	14	addition	addition	NOUN
ct-12609	65	15	there	there	PRON
ct-12609	65	16	are	be	VERB
ct-12609	65	17	changes	change	NOUN
ct-12609	65	18	in	in	ADP
ct-12609	65	19	weight	weight	NOUN
ct-12609	65	20	,	,	PUNCT
ct-12609	65	21	unusual	unusual	ADJ
ct-12609	65	22	fat	fat	ADJ
ct-12609	65	23	accumulation	accumulation	NOUN
ct-12609	65	24	at	at	ADP
ct-12609	65	25	the	the	DET
ct-12609	65	26	neck	neck	NOUN
ct-12609	65	27	,	,	PUNCT
ct-12609	65	28	tail	tail	NOUN
ct-12609	65	29	head	head	NOUN
ct-12609	65	30	and	and	CCONJ
ct-12609	65	31	over	over	ADP
ct-12609	65	32	the	the	DET
ct-12609	65	33	croup	croup	NOUN
ct-12609	65	34	(	(	PUNCT
ct-12609	65	35	29	29	NUM
ct-12609	65	36	to	to	PART
ct-12609	65	37	67	67	NUM
ct-12609	65	38	%	%	NOUN
ct-12609	65	39	)	)	PUNCT
ct-12609	65	40	.	.	PUNCT
ct-12609	66	1	obesity	obesity	NOUN
ct-12609	66	2	is	be	AUX
ct-12609	66	3	believed	believe	VERB
ct-12609	66	4	to	to	PART
ct-12609	66	5	be	be	AUX
ct-12609	66	6	the	the	DET
ct-12609	66	7	underlying	underlying	ADJ
ct-12609	66	8	factor	factor	NOUN
ct-12609	66	9	for	for	ADP
ct-12609	66	10	horses	horse	NOUN
ct-12609	66	11	with	with	ADP
ct-12609	66	12	ms	ms	PROPN
ct-12609	66	13	to	to	PART
ct-12609	66	14	develop	develop	VERB
ct-12609	66	15	ppid	ppid	NOUN
ct-12609	66	16	at	at	ADP
ct-12609	66	17	a	a	DET
ct-12609	66	18	younger	young	ADJ
ct-12609	66	19	age	age	NOUN
ct-12609	66	20	than	than	ADP
ct-12609	66	21	average	average	ADJ
ct-12609	66	22	.	.	PUNCT
ct-12609	67	1	chronic	chronic	ADJ
ct-12609	67	2	obesity	obesity	NOUN
ct-12609	67	3	is	be	AUX
ct-12609	67	4	thought	think	VERB
ct-12609	67	5	to	to	PART
ct-12609	67	6	result	result	VERB
ct-12609	67	7	from	from	ADP
ct-12609	67	8	a	a	DET
ct-12609	67	9	pro	pro	ADJ
ct-12609	67	10	-	-	ADJ
ct-12609	67	11	inflammatory	inflammatory	ADJ
ct-12609	67	12	and	and	CCONJ
ct-12609	67	13	pro	pro	ADJ
ct-12609	67	14	-	-	ADJ
ct-12609	67	15	oxidative	oxidative	ADJ
ct-12609	67	16	condition	condition	NOUN
ct-12609	67	17	that	that	PRON
ct-12609	67	18	may	may	AUX
ct-12609	67	19	accelerate	accelerate	VERB
ct-12609	67	20	degeneration	degeneration	NOUN
ct-12609	67	21	of	of	ADP
ct-12609	67	22	dopaminergic	dopaminergic	ADJ
ct-12609	67	23	neurons.7	neurons.7	NOUN
ct-12609	67	24	other	other	ADJ
ct-12609	67	25	characteristics	characteristic	NOUN
ct-12609	67	26	are	be	AUX
ct-12609	67	27	muscle	muscle	NOUN
ct-12609	67	28	atrophy	atrophy	NOUN
ct-12609	67	29	(	(	PUNCT
ct-12609	67	30	protein	protein	NOUN
ct-12609	67	31	catabolism	catabolism	NOUN
ct-12609	67	32	)	)	PUNCT
ct-12609	67	33	,	,	PUNCT
ct-12609	67	34	immunosuppression	immunosuppression	NOUN
ct-12609	67	35	(	(	PUNCT
ct-12609	67	36	and	and	CCONJ
ct-12609	67	37	consequent	consequent	ADJ
ct-12609	67	38	predisposition	predisposition	NOUN
ct-12609	67	39	to	to	ADP
ct-12609	67	40	retarded	retarded	ADJ
ct-12609	67	41	wound	wound	NOUN
ct-12609	67	42	healing	healing	NOUN
ct-12609	67	43	and	and	CCONJ
ct-12609	67	44	infections	infection	NOUN
ct-12609	67	45	such	such	ADJ
ct-12609	67	46	as	as	ADP
ct-12609	67	47	endometritis	endometritis	NOUN
ct-12609	67	48	and	and	CCONJ
ct-12609	67	49	sole	sole	ADJ
ct-12609	67	50	abscesses	abscess	NOUN
ct-12609	67	51	)	)	PUNCT
ct-12609	67	52	,	,	PUNCT
ct-12609	67	53	polydipsia	polydipsia	NOUN
ct-12609	67	54	and	and	CCONJ
ct-12609	67	55	polyuria	polyuria	NOUN
ct-12609	67	56	(	(	PUNCT
ct-12609	67	57	25	25	NUM
ct-12609	67	58	%	%	NOUN
ct-12609	67	59	)	)	PUNCT
ct-12609	67	60	,	,	PUNCT
ct-12609	67	61	lethargy	lethargy	NOUN
ct-12609	67	62	,	,	PUNCT
ct-12609	67	63	tachypnea	tachypnea	NOUN
ct-12609	67	64	,	,	PUNCT
ct-12609	67	65	hyperhidrosis	hyperhidrosis	NOUN
ct-12609	67	66	(	(	PUNCT
ct-12609	67	67	65	65	NUM
ct-12609	67	68	%	%	NOUN
ct-12609	67	69	)	)	PUNCT
ct-12609	67	70	and	and	CCONJ
ct-12609	68	1	occasionally	occasionally	ADV
ct-12609	68	2	,	,	PUNCT
ct-12609	68	3	neurologic	neurologic	ADJ
ct-12609	68	4	impairment.6,14	impairment.6,14	ADP
ct-12609	68	5	laminitis	laminitis	NOUN
ct-12609	68	6	occurs	occur	VERB
ct-12609	68	7	in	in	ADP
ct-12609	68	8	50	50	NUM
ct-12609	68	9	%	%	NOUN
ct-12609	68	10	of	of	ADP
ct-12609	68	11	advanced	advanced	ADJ
ct-12609	68	12	cases	case	NOUN
ct-12609	68	13	.	.	PUNCT
ct-12609	69	1	one	one	NUM
ct-12609	69	2	explanation	explanation	NOUN
ct-12609	69	3	is	be	AUX
ct-12609	69	4	that	that	SCONJ
ct-12609	69	5	excess	excess	NOUN
ct-12609	69	6	of	of	ADP
ct-12609	69	7	corticoids	corticoid	NOUN
ct-12609	69	8	promote	promote	VERB
ct-12609	69	9	laminar	laminar	ADJ
ct-12609	69	10	vasoconstriction	vasoconstriction	NOUN
ct-12609	69	11	.	.	PUNCT
ct-12609	70	1	the	the	DET
ct-12609	70	2	presence	presence	NOUN
ct-12609	70	3	of	of	ADP
ct-12609	70	4	ir	ir	PROPN
ct-12609	70	5	seems	seem	VERB
ct-12609	70	6	to	to	PART
ct-12609	70	7	exacerbate	exacerbate	VERB
ct-12609	70	8	the	the	DET
ct-12609	70	9	condition	condition	NOUN
ct-12609	70	10	.	.	PUNCT
ct-12609	71	1	broodmares	broodmare	NOUN
ct-12609	71	2	may	may	AUX
ct-12609	71	3	show	show	VERB
ct-12609	71	4	persistent	persistent	ADJ
ct-12609	71	5	lactation	lactation	NOUN
ct-12609	71	6	(	(	PUNCT
ct-12609	71	7	hyperprolactinemia	hyperprolactinemia	INTJ
ct-12609	71	8	)	)	PUNCT
ct-12609	71	9	,	,	PUNCT
ct-12609	71	10	low	low	ADJ
ct-12609	71	11	grade	grade	NOUN
ct-12609	71	12	endometritis	endometritis	NOUN
ct-12609	71	13	(	(	PUNCT
ct-12609	71	14	immunosuppression	immunosuppression	NOUN
ct-12609	71	15	)	)	PUNCT
ct-12609	71	16	and	and	CCONJ
ct-12609	71	17	anovulatory	anovulatory	NOUN
ct-12609	71	18	follicles	follicle	NOUN
ct-12609	71	19	during	during	ADP
ct-12609	71	20	the	the	DET
ct-12609	71	21	cyclic	cyclic	ADJ
ct-12609	71	22	season.7,9	season.7,9	PROPN
ct-12609	71	23	in	in	ADP
ct-12609	71	24	humans	human	NOUN
ct-12609	71	25	,	,	PUNCT
ct-12609	71	26	23	23	NUM
ct-12609	71	27	%	%	NOUN
ct-12609	71	28	of	of	ADP
ct-12609	71	29	cushing	cushing	NOUN
ct-12609	71	30	’s	’s	PART
ct-12609	71	31	patients	patient	NOUN
ct-12609	71	32	with	with	ADP
ct-12609	71	33	persistent	persistent	ADJ
ct-12609	71	34	lactation	lactation	NOUN
ct-12609	71	35	and	and	CCONJ
ct-12609	71	36	amenorrhea	amenorrhea	NOUN
ct-12609	71	37	(	(	PUNCT
ct-12609	71	38	due	due	ADP
ct-12609	71	39	to	to	ADP
ct-12609	71	40	gnrh	gnrh	NOUN
ct-12609	71	41	inhibition	inhibition	NOUN
ct-12609	71	42	by	by	ADP
ct-12609	71	43	prolactin	prolactin	NOUN
ct-12609	71	44	)	)	PUNCT
ct-12609	71	45	have	have	AUX
ct-12609	71	46	increased	increase	VERB
ct-12609	71	47	prolactin	prolactin	ADJ
ct-12609	71	48	concentrations	concentration	NOUN
ct-12609	71	49	.	.	PUNCT
ct-12609	72	1	the	the	DET
ct-12609	72	2	increase	increase	NOUN
ct-12609	72	3	in	in	ADP
ct-12609	72	4	prolactin	prolactin	NOUN
ct-12609	72	5	is	be	AUX
ct-12609	72	6	due	due	ADJ
ct-12609	72	7	to	to	ADP
ct-12609	72	8	excessive	excessive	ADJ
ct-12609	72	9	production	production	NOUN
ct-12609	72	10	and	and	CCONJ
ct-12609	72	11	secretion	secretion	NOUN
ct-12609	72	12	by	by	ADP
ct-12609	72	13	corticotroph	corticotroph	ADJ
ct-12609	72	14	adenomas	adenoma	NOUN
ct-12609	72	15	or	or	CCONJ
ct-12609	72	16	an	an	DET
ct-12609	72	17	alteration	alteration	NOUN
ct-12609	72	18	of	of	ADP
ct-12609	72	19	the	the	DET
ct-12609	72	20	regulation	regulation	NOUN
ct-12609	72	21	at	at	ADP
ct-12609	72	22	the	the	DET
ct-12609	72	23	dopaminergic	dopaminergic	ADJ
ct-12609	72	24	neurons.6,9,12	neurons.6,9,12	NOUN
ct-12609	72	25	491	491	NUM
ct-12609	72	26	the	the	DET
ct-12609	72	27	most	most	ADV
ct-12609	72	28	common	common	ADJ
ct-12609	72	29	biochemical	biochemical	ADJ
ct-12609	72	30	abnormality	abnormality	NOUN
ct-12609	72	31	in	in	ADP
ct-12609	72	32	ppid	ppid	NOUN
ct-12609	72	33	is	be	AUX
ct-12609	72	34	hyperglycemia	hyperglycemia	NOUN
ct-12609	72	35	and	and	CCONJ
ct-12609	72	36	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	72	37	/	/	SYM
ct-12609	72	38	ir	ir	PROPN
ct-12609	72	39	.	.	PUNCT
ct-12609	73	1	other	other	ADJ
ct-12609	73	2	findings	finding	NOUN
ct-12609	73	3	include	include	VERB
ct-12609	73	4	increased	increase	VERB
ct-12609	73	5	hepatic	hepatic	ADJ
ct-12609	73	6	enzymes	enzyme	NOUN
ct-12609	73	7	,	,	PUNCT
ct-12609	73	8	cholesterol	cholesterol	NOUN
ct-12609	73	9	and	and	CCONJ
ct-12609	73	10	triglycerides	triglyceride	NOUN
ct-12609	73	11	.	.	PUNCT
ct-12609	74	1	horses	horse	NOUN
ct-12609	74	2	can	can	AUX
ct-12609	74	3	also	also	ADV
ct-12609	74	4	have	have	VERB
ct-12609	74	5	mild	mild	ADJ
ct-12609	74	6	anemia	anemia	NOUN
ct-12609	74	7	,	,	PUNCT
ct-12609	74	8	neutrophilia	neutrophilia	NOUN
ct-12609	74	9	and	and	CCONJ
ct-12609	74	10	lymphopenia	lymphopenia	NOUN
ct-12609	74	11	.	.	PUNCT
ct-12609	75	1	diagnosis	diagnosis	NOUN
ct-12609	75	2	presence	presence	NOUN
ct-12609	75	3	of	of	ADP
ct-12609	75	4	hirsutism	hirsutism	NOUN
ct-12609	75	5	had	have	VERB
ct-12609	75	6	greater	great	ADJ
ct-12609	75	7	diagnostic	diagnostic	ADJ
ct-12609	75	8	accuracy	accuracy	NOUN
ct-12609	75	9	than	than	ADP
ct-12609	75	10	any	any	DET
ct-12609	75	11	endocrinological	endocrinological	ADJ
ct-12609	75	12	test	test	NOUN
ct-12609	75	13	alone	alone	ADV
ct-12609	75	14	or	or	CCONJ
ct-12609	75	15	in	in	ADP
ct-12609	75	16	combination.10	combination.10	NOUN
ct-12609	75	17	affected	affect	VERB
ct-12609	75	18	horses	horse	NOUN
ct-12609	75	19	are	be	AUX
ct-12609	75	20	usually	usually	ADV
ct-12609	75	21	aged	aged	ADJ
ct-12609	75	22	(	(	PUNCT
ct-12609	75	23	8	8	NUM
ct-12609	75	24	to	to	PART
ct-12609	75	25	20/30	20/30	NUM
ct-12609	75	26	years	year	NOUN
ct-12609	75	27	old	old	ADJ
ct-12609	75	28	)	)	PUNCT
ct-12609	75	29	,	,	PUNCT
ct-12609	75	30	overweight	overweight	ADJ
ct-12609	75	31	,	,	PUNCT
ct-12609	75	32	with	with	SCONJ
ct-12609	75	33	the	the	DET
ct-12609	75	34	characteristic	characteristic	ADJ
ct-12609	75	35	distribution	distribution	NOUN
ct-12609	75	36	of	of	ADP
ct-12609	75	37	body	body	NOUN
ct-12609	75	38	fat	fat	NOUN
ct-12609	75	39	(	(	PUNCT
ct-12609	75	40	neck	neck	NOUN
ct-12609	75	41	,	,	PUNCT
ct-12609	75	42	shoulders	shoulder	NOUN
ct-12609	75	43	,	,	PUNCT
ct-12609	75	44	)	)	PUNCT
ct-12609	75	45	,	,	PUNCT
ct-12609	75	46	laminitis	laminitis	NOUN
ct-12609	75	47	,	,	PUNCT
ct-12609	75	48	and	and	CCONJ
ct-12609	75	49	abnormal	abnormal	ADJ
ct-12609	75	50	estrous	estrous	ADJ
ct-12609	75	51	cycles.7,8,9,10	cycles.7,8,9,10	NOUN
ct-12609	75	52	dynamic	dynamic	ADJ
ct-12609	75	53	endocrinologic	endocrinologic	ADJ
ct-12609	75	54	diagnostic	diagnostic	ADJ
ct-12609	75	55	tests	test	VERB
ct-12609	75	56	the	the	DET
ct-12609	75	57	dynamic	dynamic	ADJ
ct-12609	75	58	endocrinologic	endocrinologic	ADJ
ct-12609	75	59	diagnostic	diagnostic	ADJ
ct-12609	75	60	tests	test	NOUN
ct-12609	75	61	consist	consist	VERB
ct-12609	75	62	of	of	ADP
ct-12609	75	63	the	the	DET
ct-12609	75	64	overnight	overnight	ADJ
ct-12609	75	65	dexamethasone	dexamethasone	NOUN
ct-12609	75	66	suppression	suppression	NOUN
ct-12609	75	67	test	test	NOUN
ct-12609	75	68	(	(	PUNCT
ct-12609	75	69	dst	dst	PROPN
ct-12609	75	70	)	)	PUNCT
ct-12609	75	71	,	,	PUNCT
ct-12609	75	72	thyrotropin	thyrotropin	NOUN
ct-12609	75	73	-	-	PUNCT
ct-12609	75	74	releasing	release	VERB
ct-12609	75	75	hormone	hormone	NOUN
ct-12609	75	76	(	(	PUNCT
ct-12609	75	77	trh	trh	NOUN
ct-12609	75	78	)	)	PUNCT
ct-12609	75	79	stimulation	stimulation	NOUN
ct-12609	75	80	test	test	NOUN
ct-12609	75	81	and	and	CCONJ
ct-12609	75	82	the	the	DET
ct-12609	75	83	cortisol	cortisol	ADJ
ct-12609	75	84	rhythm	rhythm	NOUN
ct-12609	75	85	assay	assay	VERB
ct-12609	75	86	.	.	PUNCT
ct-12609	76	1	dst	dst	PROPN
ct-12609	76	2	.	.	PUNCT
ct-12609	77	1	in	in	ADP
ct-12609	77	2	normal	normal	ADJ
ct-12609	77	3	horses	horse	NOUN
ct-12609	77	4	,	,	PUNCT
ct-12609	77	5	administration	administration	NOUN
ct-12609	77	6	of	of	ADP
ct-12609	77	7	dexamethasone	dexamethasone	NOUN
ct-12609	77	8	(	(	PUNCT
ct-12609	77	9	20	20	NUM
ct-12609	77	10	mg	mg	PROPN
ct-12609	77	11	im/500	im/500	PROPN
ct-12609	77	12	kg	kg	NOUN
ct-12609	77	13	)	)	PUNCT
ct-12609	77	14	decreases	decrease	VERB
ct-12609	77	15	the	the	DET
ct-12609	77	16	acth	acth	NOUN
ct-12609	77	17	release	release	NOUN
ct-12609	77	18	from	from	ADP
ct-12609	77	19	the	the	DET
ct-12609	77	20	pituitary	pituitary	NOUN
ct-12609	77	21	,	,	PUNCT
ct-12609	77	22	resulting	result	VERB
ct-12609	77	23	in	in	ADP
ct-12609	77	24	a	a	DET
ct-12609	77	25	cortisol	cortisol	NOUN
ct-12609	77	26	serum	serum	NOUN
ct-12609	77	27	concentration	concentration	NOUN
ct-12609	77	28	of	of	ADP
ct-12609	77	29	<	<	X
ct-12609	77	30	1	1	NUM
ct-12609	77	31	µg	µg	ADV
ct-12609	77	32	or	or	CCONJ
ct-12609	77	33	10	10	NUM
ct-12609	77	34	ng	ng	PROPN
ct-12609	77	35	/	/	SYM
ct-12609	77	36	dl	dl	PROPN
ct-12609	77	37	approximately	approximately	ADV
ct-12609	77	38	19	19	NUM
ct-12609	77	39	hours	hour	NOUN
ct-12609	77	40	after	after	ADP
ct-12609	77	41	injection	injection	NOUN
ct-12609	77	42	.	.	PUNCT
ct-12609	78	1	conversely	conversely	ADV
ct-12609	78	2	,	,	PUNCT
ct-12609	78	3	in	in	ADP
ct-12609	78	4	horses	horse	NOUN
ct-12609	78	5	with	with	ADP
ct-12609	78	6	ppid	ppid	NOUN
ct-12609	78	7	,	,	PUNCT
ct-12609	78	8	serum	serum	NOUN
ct-12609	78	9	cortisol	cortisol	ADJ
ct-12609	78	10	concentration	concentration	NOUN
ct-12609	78	11	does	do	AUX
ct-12609	78	12	not	not	PART
ct-12609	78	13	decrease	decrease	VERB
ct-12609	78	14	after	after	ADP
ct-12609	78	15	dexamethasone	dexamethasone	NOUN
ct-12609	78	16	administration	administration	NOUN
ct-12609	78	17	due	due	ADP
ct-12609	78	18	to	to	ADP
ct-12609	78	19	continuous	continuous	ADJ
ct-12609	78	20	acth	acth	NOUN
ct-12609	78	21	release	release	NOUN
ct-12609	78	22	.	.	PUNCT
ct-12609	79	1	unfortunately	unfortunately	ADV
ct-12609	79	2	,	,	PUNCT
ct-12609	79	3	this	this	DET
ct-12609	79	4	gold	gold	NOUN
ct-12609	79	5	-	-	PUNCT
ct-12609	79	6	standard	standard	NOUN
ct-12609	79	7	test	test	NOUN
ct-12609	79	8	loses	lose	VERB
ct-12609	79	9	accuracy	accuracy	NOUN
ct-12609	79	10	(	(	PUNCT
ct-12609	79	11	sensitivity	sensitivity	NOUN
ct-12609	79	12	and	and	CCONJ
ct-12609	79	13	specificity	specificity	NOUN
ct-12609	79	14	)	)	PUNCT
ct-12609	79	15	early	early	ADV
ct-12609	79	16	in	in	ADP
ct-12609	79	17	the	the	DET
ct-12609	79	18	condition	condition	NOUN
ct-12609	79	19	when	when	SCONJ
ct-12609	79	20	there	there	PRON
ct-12609	79	21	is	be	VERB
ct-12609	79	22	still	still	ADV
ct-12609	79	23	some	some	DET
ct-12609	79	24	feedback	feedback	NOUN
ct-12609	79	25	from	from	ADP
ct-12609	79	26	the	the	DET
ct-12609	79	27	hypothalamic	hypothalamic	ADJ
ct-12609	79	28	-	-	PUNCT
ct-12609	79	29	pituitary	pituitary	ADJ
ct-12609	79	30	axis	axis	NOUN
ct-12609	79	31	,	,	PUNCT
ct-12609	79	32	as	as	SCONJ
ct-12609	79	33	it	it	PRON
ct-12609	79	34	appears	appear	VERB
ct-12609	79	35	that	that	SCONJ
ct-12609	79	36	loss	loss	NOUN
ct-12609	79	37	of	of	ADP
ct-12609	79	38	suppression	suppression	NOUN
ct-12609	79	39	by	by	ADP
ct-12609	79	40	dexamethasone	dexamethasone	NOUN
ct-12609	79	41	is	be	AUX
ct-12609	79	42	a	a	DET
ct-12609	79	43	late	late	ADJ
ct-12609	79	44	event	event	NOUN
ct-12609	79	45	in	in	ADP
ct-12609	79	46	the	the	DET
ct-12609	79	47	pathogenesis.10	pathogenesis.10	NOUN
ct-12609	79	48	the	the	DET
ct-12609	79	49	dst	dst	NOUN
ct-12609	79	50	results	result	NOUN
ct-12609	79	51	are	be	AUX
ct-12609	79	52	also	also	ADV
ct-12609	79	53	affected	affect	VERB
ct-12609	79	54	by	by	ADP
ct-12609	79	55	the	the	DET
ct-12609	79	56	season	season	NOUN
ct-12609	79	57	of	of	ADP
ct-12609	79	58	the	the	DET
ct-12609	79	59	year	year	NOUN
ct-12609	79	60	since	since	SCONJ
ct-12609	79	61	the	the	DET
ct-12609	79	62	pituitary	pituitary	ADJ
ct-12609	79	63	pars	par	NOUN
ct-12609	79	64	intermedia	intermedia	PROPN
ct-12609	79	65	produces	produce	VERB
ct-12609	79	66	more	more	ADJ
ct-12609	79	67	hormones	hormone	NOUN
ct-12609	79	68	during	during	ADP
ct-12609	79	69	the	the	DET
ct-12609	79	70	fall	fall	NOUN
ct-12609	79	71	(	(	PUNCT
ct-12609	79	72	“	"	PUNCT
ct-12609	79	73	survival	survival	NOUN
ct-12609	79	74	mechanism	mechanism	NOUN
ct-12609	79	75	”	"	PUNCT
ct-12609	79	76	)	)	PUNCT
ct-12609	79	77	.	.	PUNCT
ct-12609	80	1	one	one	NUM
ct-12609	80	2	study	study	NOUN
ct-12609	80	3	showed	show	VERB
ct-12609	80	4	that	that	SCONJ
ct-12609	80	5	falsepositive	falsepositive	ADJ
ct-12609	80	6	overnight	overnight	ADV
ct-12609	80	7	dst	dst	PROPN
ct-12609	80	8	results	result	NOUN
ct-12609	80	9	were	be	AUX
ct-12609	80	10	common	common	ADJ
ct-12609	80	11	when	when	SCONJ
ct-12609	80	12	horses	horse	NOUN
ct-12609	80	13	or	or	CCONJ
ct-12609	80	14	ponies	pony	NOUN
ct-12609	80	15	were	be	AUX
ct-12609	80	16	tested	test	VERB
ct-12609	80	17	in	in	ADP
ct-12609	80	18	the	the	DET
ct-12609	80	19	fall.1	fall.1	ADV
ct-12609	80	20	492	492	NUM
ct-12609	80	21	trh	trh	NOUN
ct-12609	80	22	stimulation	stimulation	NOUN
ct-12609	80	23	test	test	NOUN
ct-12609	80	24	.	.	PUNCT
ct-12609	81	1	horses	horse	NOUN
ct-12609	81	2	with	with	ADP
ct-12609	81	3	ppid	ppid	PROPN
ct-12609	81	4	show	show	VERB
ct-12609	81	5	an	an	DET
ct-12609	81	6	increase	increase	NOUN
ct-12609	81	7	(	(	PUNCT
ct-12609	81	8	30	30	NUM
ct-12609	81	9	to	to	PART
ct-12609	81	10	50	50	NUM
ct-12609	81	11	%	%	NOUN
ct-12609	81	12	from	from	ADP
ct-12609	81	13	baseline	baseline	NOUN
ct-12609	81	14	)	)	PUNCT
ct-12609	81	15	in	in	ADP
ct-12609	81	16	serum	serum	NOUN
ct-12609	81	17	cortisol	cortisol	NOUN
ct-12609	81	18	concentration	concentration	NOUN
ct-12609	81	19	30	30	NUM
ct-12609	81	20	to	to	PART
ct-12609	81	21	90	90	NUM
ct-12609	81	22	min	min	NOUN
ct-12609	81	23	after	after	ADP
ct-12609	81	24	trh	trh	PROPN
ct-12609	81	25	administration	administration	PROPN
ct-12609	81	26	(	(	PUNCT
ct-12609	81	27	0.5	0.5	NUM
ct-12609	81	28	to	to	PART
ct-12609	81	29	1	1	NUM
ct-12609	81	30	mg	mg	PROPN
ct-12609	81	31	,	,	PUNCT
ct-12609	81	32	iv	iv	X
ct-12609	81	33	)	)	PUNCT
ct-12609	81	34	whereas	whereas	SCONJ
ct-12609	81	35	normal	normal	ADJ
ct-12609	81	36	horses	horse	NOUN
ct-12609	81	37	do	do	VERB
ct-12609	81	38	not.15	not.15	NOUN
ct-12609	81	39	normally	normally	ADV
ct-12609	81	40	,	,	PUNCT
ct-12609	81	41	trh	trh	PROPN
ct-12609	81	42	produced	produce	VERB
ct-12609	81	43	by	by	ADP
ct-12609	81	44	the	the	DET
ct-12609	81	45	hypothalamus	hypothalamus	PROPN
ct-12609	81	46	stimulates	stimulate	VERB
ct-12609	81	47	tsh	tsh	NOUN
ct-12609	81	48	release	release	NOUN
ct-12609	81	49	from	from	ADP
ct-12609	81	50	the	the	DET
ct-12609	81	51	pituitary	pituitary	NOUN
ct-12609	81	52	.	.	PUNCT
ct-12609	82	1	however	however	ADV
ct-12609	82	2	,	,	PUNCT
ct-12609	82	3	in	in	ADP
ct-12609	82	4	ppid	ppid	NOUN
ct-12609	82	5	,	,	PUNCT
ct-12609	82	6	exogenous	exogenous	ADJ
ct-12609	82	7	trh	trh	NOUN
ct-12609	82	8	stimulates	stimulate	VERB
ct-12609	82	9	acth	acth	NOUN
ct-12609	82	10	and	and	CCONJ
ct-12609	82	11	hence	hence	ADV
ct-12609	82	12	,	,	PUNCT
ct-12609	82	13	cortisol	cortisol	NOUN
ct-12609	82	14	release	release	NOUN
ct-12609	82	15	.	.	PUNCT
ct-12609	83	1	it	it	PRON
ct-12609	83	2	appears	appear	VERB
ct-12609	83	3	to	to	PART
ct-12609	83	4	be	be	AUX
ct-12609	83	5	due	due	ADJ
ct-12609	83	6	to	to	ADP
ct-12609	83	7	an	an	DET
ct-12609	83	8	up	up	ADJ
ct-12609	83	9	-	-	PUNCT
ct-12609	83	10	regulation	regulation	NOUN
ct-12609	83	11	and	and	CCONJ
ct-12609	83	12	expression	expression	NOUN
ct-12609	83	13	of	of	ADP
ct-12609	83	14	trh	trh	NOUN
ct-12609	83	15	receptors	receptor	NOUN
ct-12609	83	16	in	in	ADP
ct-12609	83	17	hyperplastic	hyperplastic	ADJ
ct-12609	83	18	/	/	SYM
ct-12609	83	19	adenomatous	adenomatous	ADJ
ct-12609	83	20	corticotropes	corticotrope	NOUN
ct-12609	83	21	in	in	ADP
ct-12609	83	22	the	the	DET
ct-12609	83	23	pituitary	pituitary	ADJ
ct-12609	83	24	pars	par	NOUN
ct-12609	83	25	distalis	distali	NOUN
ct-12609	83	26	and	and	CCONJ
ct-12609	83	27	intermedia.10,14	intermedia.10,14	ADV
ct-12609	83	28	this	this	DET
ct-12609	83	29	test	test	NOUN
ct-12609	83	30	is	be	AUX
ct-12609	83	31	safe	safe	ADJ
ct-12609	83	32	to	to	PART
ct-12609	83	33	perform	perform	VERB
ct-12609	83	34	in	in	ADP
ct-12609	83	35	laminitic	laminitic	ADJ
ct-12609	83	36	horses	horse	NOUN
ct-12609	83	37	.	.	PUNCT
ct-12609	84	1	it	it	PRON
ct-12609	84	2	has	have	AUX
ct-12609	84	3	not	not	PART
ct-12609	84	4	been	be	AUX
ct-12609	84	5	critically	critically	ADV
ct-12609	84	6	evaluated	evaluate	VERB
ct-12609	84	7	in	in	ADP
ct-12609	84	8	horses	horse	NOUN
ct-12609	84	9	early	early	ADV
ct-12609	84	10	in	in	ADP
ct-12609	84	11	the	the	DET
ct-12609	84	12	disease	disease	NOUN
ct-12609	84	13	process	process	NOUN
ct-12609	84	14	.	.	PUNCT
ct-12609	85	1	(	(	PUNCT
ct-12609	85	2	diurnal	diurnal	ADJ
ct-12609	85	3	)	)	PUNCT
ct-12609	85	4	cortisol	cortisol	NOUN
ct-12609	85	5	rhythm	rhythm	NOUN
ct-12609	85	6	assay	assay	VERB
ct-12609	85	7	.	.	PUNCT
ct-12609	86	1	this	this	DET
ct-12609	86	2	assay	assay	NOUN
ct-12609	86	3	is	be	AUX
ct-12609	86	4	based	base	VERB
ct-12609	86	5	on	on	ADP
ct-12609	86	6	the	the	DET
ct-12609	86	7	observation	observation	NOUN
ct-12609	86	8	that	that	PRON
ct-12609	86	9	horses	horse	NOUN
ct-12609	86	10	with	with	ADP
ct-12609	86	11	ppid	ppid	PROPN
ct-12609	86	12	have	have	VERB
ct-12609	86	13	a	a	DET
ct-12609	86	14	loss	loss	NOUN
ct-12609	86	15	of	of	ADP
ct-12609	86	16	the	the	DET
ct-12609	86	17	diurnal	diurnal	ADJ
ct-12609	86	18	cortisol	cortisol	ADJ
ct-12609	86	19	rhythm	rhythm	NOUN
ct-12609	86	20	(	(	PUNCT
ct-12609	86	21	normally	normally	ADV
ct-12609	86	22	high	high	ADJ
ct-12609	86	23	in	in	ADP
ct-12609	86	24	morning	morning	NOUN
ct-12609	86	25	,	,	PUNCT
ct-12609	86	26	low	low	ADJ
ct-12609	86	27	at	at	ADP
ct-12609	86	28	midnight).10,16	midnight).10,16	NUM
ct-12609	86	29	when	when	SCONJ
ct-12609	86	30	performing	perform	VERB
ct-12609	86	31	this	this	DET
ct-12609	86	32	test	test	NOUN
ct-12609	86	33	,	,	PUNCT
ct-12609	86	34	plasma	plasma	NOUN
ct-12609	86	35	cortisol	cortisol	ADJ
ct-12609	86	36	concentration	concentration	NOUN
ct-12609	86	37	is	be	AUX
ct-12609	86	38	measured	measure	VERB
ct-12609	86	39	at	at	ADP
ct-12609	86	40	8	8	NUM
ct-12609	86	41	am	am	NOUN
ct-12609	86	42	and	and	CCONJ
ct-12609	86	43	again	again	ADV
ct-12609	86	44	at	at	ADP
ct-12609	86	45	4	4	NUM
ct-12609	86	46	pm	pm	NOUN
ct-12609	86	47	.	.	PUNCT
ct-12609	87	1	a	a	DET
ct-12609	87	2	difference	difference	NOUN
ct-12609	87	3	of	of	ADP
ct-12609	87	4	less	less	ADJ
ct-12609	87	5	than	than	ADP
ct-12609	87	6	30	30	NUM
ct-12609	87	7	%	%	NOUN
ct-12609	87	8	between	between	ADP
ct-12609	87	9	the	the	DET
ct-12609	87	10	morning	morning	NOUN
ct-12609	87	11	and	and	CCONJ
ct-12609	87	12	afternoon	afternoon	NOUN
ct-12609	87	13	cortisol	cortisol	ADJ
ct-12609	87	14	concentration	concentration	NOUN
ct-12609	87	15	is	be	AUX
ct-12609	87	16	considered	consider	VERB
ct-12609	87	17	to	to	PART
ct-12609	87	18	be	be	AUX
ct-12609	87	19	suggestive	suggestive	ADJ
ct-12609	87	20	of	of	ADP
ct-12609	87	21	ppid	ppid	NOUN
ct-12609	87	22	.	.	PUNCT
ct-12609	88	1	however	however	ADV
ct-12609	88	2	,	,	PUNCT
ct-12609	88	3	this	this	DET
ct-12609	88	4	test	test	NOUN
ct-12609	88	5	has	have	AUX
ct-12609	88	6	not	not	PART
ct-12609	88	7	been	be	AUX
ct-12609	88	8	validated	validate	VERB
ct-12609	88	9	and	and	CCONJ
ct-12609	88	10	several	several	ADJ
ct-12609	88	11	factors	factor	NOUN
ct-12609	88	12	such	such	ADJ
ct-12609	88	13	as	as	ADP
ct-12609	88	14	fasting	fast	VERB
ct-12609	88	15	,	,	PUNCT
ct-12609	88	16	changes	change	NOUN
ct-12609	88	17	in	in	ADP
ct-12609	88	18	stabling	stabling	NOUN
ct-12609	88	19	or	or	CCONJ
ct-12609	88	20	laminitis	laminitis	NOUN
ct-12609	88	21	can	can	AUX
ct-12609	88	22	increase	increase	VERB
ct-12609	88	23	plasma	plasma	NOUN
ct-12609	88	24	cortisol	cortisol	ADJ
ct-12609	88	25	concentration	concentration	NOUN
ct-12609	88	26	in	in	ADP
ct-12609	88	27	the	the	DET
ct-12609	88	28	horse	horse	NOUN
ct-12609	88	29	.	.	PUNCT
ct-12609	89	1	combined	combine	VERB
ct-12609	89	2	dst	dst	PROPN
ct-12609	89	3	and	and	CCONJ
ct-12609	89	4	trh	trh	NOUN
ct-12609	89	5	stimulation	stimulation	NOUN
ct-12609	89	6	test	test	NOUN
ct-12609	89	7	.	.	PUNCT
ct-12609	90	1	administration	administration	NOUN
ct-12609	90	2	of	of	ADP
ct-12609	90	3	dexamethasone	dexamethasone	NOUN
ct-12609	90	4	before	before	SCONJ
ct-12609	90	5	trh	trh	PROPN
ct-12609	90	6	should	should	AUX
ct-12609	90	7	suppress	suppress	VERB
ct-12609	90	8	acth	acth	NOUN
ct-12609	90	9	release	release	NOUN
ct-12609	90	10	from	from	ADP
ct-12609	90	11	the	the	DET
ct-12609	90	12	pituitary	pituitary	ADJ
ct-12609	90	13	par	par	NOUN
ct-12609	90	14	distalis	distalis	PROPN
ct-12609	90	15	therefore	therefore	ADV
ct-12609	90	16	,	,	PUNCT
ct-12609	90	17	any	any	DET
ct-12609	90	18	increase	increase	NOUN
ct-12609	90	19	in	in	ADP
ct-12609	90	20	cortisol	cortisol	NOUN
ct-12609	90	21	after	after	SCONJ
ct-12609	90	22	trh	trh	PROPN
ct-12609	90	23	administration	administration	PROPN
ct-12609	90	24	is	be	AUX
ct-12609	90	25	attributed	attribute	VERB
ct-12609	90	26	to	to	ADP
ct-12609	90	27	pars	pars	PROPN
ct-12609	90	28	intermedia	intermedia	PROPN
ct-12609	90	29	corticotropes	corticotropes	PROPN
ct-12609	90	30	.	.	PUNCT
ct-12609	91	1	in	in	ADP
ct-12609	91	2	performing	perform	VERB
ct-12609	91	3	this	this	DET
ct-12609	91	4	test	test	NOUN
ct-12609	91	5	,	,	PUNCT
ct-12609	91	6	a	a	DET
ct-12609	91	7	baseline	baseline	ADJ
ct-12609	91	8	plasma	plasma	NOUN
ct-12609	91	9	cortisol	cortisol	NOUN
ct-12609	91	10	concentration	concentration	NOUN
ct-12609	91	11	is	be	AUX
ct-12609	91	12	obtained	obtain	VERB
ct-12609	91	13	followed	follow	VERB
ct-12609	91	14	by	by	ADP
ct-12609	91	15	administration	administration	NOUN
ct-12609	91	16	of	of	ADP
ct-12609	91	17	dexamethasone	dexamethasone	NOUN
ct-12609	91	18	(	(	PUNCT
ct-12609	91	19	20	20	NUM
ct-12609	91	20	mg	mg	PROPN
ct-12609	91	21	,	,	PUNCT
ct-12609	91	22	im/500	im/500	PROPN
ct-12609	91	23	kg	kg	PROPN
ct-12609	91	24	)	)	PUNCT
ct-12609	91	25	.	.	PUNCT
ct-12609	92	1	three	three	NUM
ct-12609	92	2	h	h	NOUN
ct-12609	92	3	after	after	SCONJ
ct-12609	92	4	the	the	DET
ct-12609	92	5	dexamethasone	dexamethasone	NOUN
ct-12609	92	6	is	be	AUX
ct-12609	92	7	given	give	VERB
ct-12609	92	8	,	,	PUNCT
ct-12609	92	9	trh	trh	NOUN
ct-12609	92	10	(	(	PUNCT
ct-12609	92	11	0.5	0.5	NUM
ct-12609	92	12	to	to	PART
ct-12609	92	13	1	1	NUM
ct-12609	92	14	mg	mg	PROPN
ct-12609	92	15	,	,	PUNCT
ct-12609	92	16	iv	iv	X
ct-12609	92	17	)	)	PUNCT
ct-12609	92	18	is	be	AUX
ct-12609	92	19	administered	administer	VERB
ct-12609	92	20	.	.	PUNCT
ct-12609	93	1	cortisol	cortisol	NOUN
ct-12609	93	2	should	should	AUX
ct-12609	93	3	be	be	AUX
ct-12609	93	4	suppressed	suppress	VERB
ct-12609	93	5	by	by	ADP
ct-12609	93	6	the	the	DET
ct-12609	93	7	trh	trh	PROPN
ct-12609	93	8	.	.	PUNCT
ct-12609	94	1	plasma	plasma	NOUN
ct-12609	94	2	cortisol	cortisol	ADJ
ct-12609	94	3	concentrations	concentration	NOUN
ct-12609	94	4	are	be	AUX
ct-12609	94	5	measured	measure	VERB
ct-12609	94	6	30	30	NUM
ct-12609	94	7	min	min	NOUN
ct-12609	94	8	and	and	CCONJ
ct-12609	94	9	21	21	NUM
ct-12609	94	10	h	h	NOUN
ct-12609	94	11	after	after	ADP
ct-12609	94	12	administration	administration	NOUN
ct-12609	94	13	of	of	ADP
ct-12609	94	14	trh	trh	PROPN
ct-12609	94	15	(	(	PUNCT
ct-12609	94	16	24	24	NUM
ct-12609	94	17	h	h	NOUN
ct-12609	94	18	after	after	ADP
ct-12609	94	19	dexamethasone	dexamethasone	NOUN
ct-12609	94	20	administration	administration	NOUN
ct-12609	94	21	)	)	PUNCT
ct-12609	94	22	.	.	PUNCT
ct-12609	95	1	a	a	DET
ct-12609	95	2	plasma	plasma	NOUN
ct-12609	95	3	cortisol	cortisol	NOUN
ct-12609	95	4	concentration	concentration	NOUN
ct-12609	95	5	>	>	X
ct-12609	95	6	1	1	NUM
ct-12609	95	7	µg	µg	NOUN
ct-12609	95	8	/	/	SYM
ct-12609	95	9	dl	dl	PROPN
ct-12609	95	10	24	24	NUM
ct-12609	95	11	h	h	NOUN
ct-12609	95	12	after	after	ADP
ct-12609	95	13	administration	administration	NOUN
ct-12609	95	14	of	of	ADP
ct-12609	95	15	493	493	NUM
ct-12609	95	16	dexamethasone	dexamethasone	NOUN
ct-12609	95	17	or	or	CCONJ
ct-12609	95	18	a	a	DET
ct-12609	95	19	>	>	SYM
ct-12609	95	20	66	66	NUM
ct-12609	95	21	%	%	NOUN
ct-12609	95	22	increase	increase	NOUN
ct-12609	95	23	in	in	ADP
ct-12609	95	24	cortisol	cortisol	ADJ
ct-12609	95	25	30	30	NUM
ct-12609	95	26	min	min	NOUN
ct-12609	95	27	after	after	SCONJ
ct-12609	95	28	trh	trh	PROPN
ct-12609	95	29	administration	administration	NOUN
ct-12609	95	30	is	be	AUX
ct-12609	95	31	considered	consider	VERB
ct-12609	95	32	diagnostic	diagnostic	ADJ
ct-12609	95	33	for	for	ADP
ct-12609	95	34	ppid.[8,10	ppid.[8,10	NOUN
ct-12609	95	35	the	the	DET
ct-12609	95	36	test	test	NOUN
ct-12609	95	37	is	be	AUX
ct-12609	95	38	expensive	expensive	ADJ
ct-12609	95	39	and	and	CCONJ
ct-12609	95	40	may	may	AUX
ct-12609	95	41	be	be	AUX
ct-12609	95	42	impractical	impractical	ADJ
ct-12609	95	43	for	for	ADP
ct-12609	95	44	the	the	DET
ct-12609	95	45	ambulatory	ambulatory	ADJ
ct-12609	95	46	clinician	clinician	NOUN
ct-12609	95	47	.	.	PUNCT
ct-12609	96	1	accuracy	accuracy	NOUN
ct-12609	96	2	of	of	ADP
ct-12609	96	3	each	each	DET
ct-12609	96	4	test	test	NOUN
ct-12609	96	5	when	when	SCONJ
ct-12609	96	6	compared	compare	VERB
ct-12609	96	7	with	with	ADP
ct-12609	96	8	histological	histological	ADJ
ct-12609	96	9	findings	finding	NOUN
ct-12609	96	10	is	be	AUX
ct-12609	96	11	dst	dst	PROPN
ct-12609	96	12	/	/	SYM
ct-12609	96	13	trh	trh	NOUN
ct-12609	96	14	81	81	NUM
ct-12609	96	15	%	%	NOUN
ct-12609	96	16	;	;	PUNCT
ct-12609	96	17	dst	dst	PROPN
ct-12609	96	18	71	71	NUM
ct-12609	96	19	%	%	NOUN
ct-12609	96	20	;	;	PUNCT
ct-12609	96	21	trh	trh	NOUN
ct-12609	96	22	71	71	NUM
ct-12609	96	23	%	%	NOUN
ct-12609	96	24	.	.	PUNCT
ct-12609	97	1	accuracy	accuracy	NOUN
ct-12609	97	2	of	of	ADP
ct-12609	97	3	hirsutism	hirsutism	NOUN
ct-12609	97	4	alone	alone	ADV
ct-12609	97	5	is	be	AUX
ct-12609	97	6	86	86	NUM
ct-12609	97	7	%	%	NOUN
ct-12609	97	8	.	.	PUNCT
ct-12609	98	1	single	single	ADJ
ct-12609	98	2	sample	sample	PROPN
ct-12609	98	3	endocrinologic	endocrinologic	NOUN
ct-12609	98	4	tests	test	VERB
ct-12609	98	5	two	two	NUM
ct-12609	98	6	single	single	ADJ
ct-12609	98	7	sample	sample	NOUN
ct-12609	98	8	endocrinological	endocrinological	ADJ
ct-12609	98	9	tests	test	NOUN
ct-12609	98	10	are	be	AUX
ct-12609	98	11	available	available	ADJ
ct-12609	98	12	and	and	CCONJ
ct-12609	98	13	include	include	VERB
ct-12609	98	14	measurement	measurement	NOUN
ct-12609	98	15	of	of	ADP
ct-12609	98	16	endogenous	endogenous	ADJ
ct-12609	98	17	release	release	NOUN
ct-12609	98	18	of	of	ADP
ct-12609	98	19	plasma	plasma	NOUN
ct-12609	98	20	adrenocorticotrophic	adrenocorticotrophic	ADJ
ct-12609	98	21	hormone	hormone	NOUN
ct-12609	98	22	(	(	PUNCT
ct-12609	98	23	acth	acth	NOUN
ct-12609	98	24	)	)	PUNCT
ct-12609	98	25	concentration	concentration	NOUN
ct-12609	98	26	and	and	CCONJ
ct-12609	98	27	insulin	insulin	NOUN
ct-12609	98	28	concentration	concentration	NOUN
ct-12609	98	29	.	.	PUNCT
ct-12609	99	1	acth	acth	NOUN
ct-12609	99	2	concentration	concentration	NOUN
ct-12609	99	3	test	test	NOUN
ct-12609	99	4	.	.	PUNCT
ct-12609	100	1	measuring	measure	VERB
ct-12609	100	2	a	a	DET
ct-12609	100	3	single	single	ADJ
ct-12609	100	4	sample	sample	NOUN
ct-12609	100	5	of	of	ADP
ct-12609	100	6	endogenous	endogenous	ADJ
ct-12609	100	7	plasma	plasma	NOUN
ct-12609	100	8	acth	acth	NOUN
ct-12609	100	9	,	,	PUNCT
ct-12609	100	10	which	which	PRON
ct-12609	100	11	is	be	AUX
ct-12609	100	12	supposedly	supposedly	ADV
ct-12609	100	13	higher	high	ADJ
ct-12609	100	14	in	in	ADP
ct-12609	100	15	horses	horse	NOUN
ct-12609	100	16	with	with	ADP
ct-12609	100	17	ppid	ppid	NOUN
ct-12609	100	18	,	,	PUNCT
ct-12609	100	19	is	be	AUX
ct-12609	100	20	not	not	PART
ct-12609	100	21	more	more	ADV
ct-12609	100	22	accurate	accurate	ADJ
ct-12609	100	23	than	than	ADP
ct-12609	100	24	the	the	DET
ct-12609	100	25	dst	dst	NOUN
ct-12609	100	26	test	test	NOUN
ct-12609	100	27	,	,	PUNCT
ct-12609	100	28	does	do	AUX
ct-12609	100	29	not	not	PART
ct-12609	100	30	detect	detect	VERB
ct-12609	100	31	early	early	ADJ
ct-12609	100	32	cases	case	NOUN
ct-12609	100	33	,	,	PUNCT
ct-12609	100	34	and	and	CCONJ
ct-12609	100	35	it	it	PRON
ct-12609	100	36	undergoes	undergo	VERB
ct-12609	100	37	daily	daily	ADJ
ct-12609	100	38	and	and	CCONJ
ct-12609	100	39	seasonal	seasonal	ADJ
ct-12609	100	40	variations	variation	NOUN
ct-12609	100	41	.	.	PUNCT
ct-12609	101	1	a	a	DET
ct-12609	101	2	reference	reference	NOUN
ct-12609	101	3	value	value	NOUN
ct-12609	101	4	of	of	ADP
ct-12609	101	5	>	>	X
ct-12609	101	6	50	50	NUM
ct-12609	101	7	pg	pg	NOUN
ct-12609	101	8	/	/	SYM
ct-12609	101	9	ml	ml	PROPN
ct-12609	101	10	is	be	AUX
ct-12609	101	11	considered	consider	VERB
ct-12609	101	12	elevated.10	elevated.10	NOUN
ct-12609	101	13	sample	sample	NOUN
ct-12609	101	14	handling	handling	NOUN
ct-12609	101	15	is	be	AUX
ct-12609	101	16	intricate	intricate	ADJ
ct-12609	101	17	.	.	PUNCT
ct-12609	102	1	blood	blood	NOUN
ct-12609	102	2	must	must	AUX
ct-12609	102	3	be	be	AUX
ct-12609	102	4	collected	collect	VERB
ct-12609	102	5	in	in	ADP
ct-12609	102	6	cold	cold	ADJ
ct-12609	102	7	plastic	plastic	NOUN
ct-12609	102	8	tubes	tube	NOUN
ct-12609	102	9	containing	contain	VERB
ct-12609	102	10	edta	edta	NOUN
ct-12609	102	11	,	,	PUNCT
ct-12609	102	12	as	as	SCONJ
ct-12609	102	13	the	the	DET
ct-12609	102	14	acth	acth	NOUN
ct-12609	102	15	can	can	AUX
ct-12609	102	16	be	be	AUX
ct-12609	102	17	absorbed	absorb	VERB
ct-12609	102	18	onto	onto	ADP
ct-12609	102	19	glass	glass	NOUN
ct-12609	102	20	and	and	CCONJ
ct-12609	102	21	degraded	degrade	VERB
ct-12609	102	22	by	by	ADP
ct-12609	102	23	proteolytic	proteolytic	ADJ
ct-12609	102	24	enzymes	enzyme	NOUN
ct-12609	102	25	in	in	ADP
ct-12609	102	26	blood	blood	NOUN
ct-12609	102	27	or	or	CCONJ
ct-12609	102	28	serum	serum	NOUN
ct-12609	102	29	.	.	PUNCT
ct-12609	103	1	it	it	PRON
ct-12609	103	2	needs	need	VERB
ct-12609	103	3	to	to	PART
ct-12609	103	4	be	be	AUX
ct-12609	103	5	centrifuged	centrifuge	VERB
ct-12609	103	6	as	as	ADV
ct-12609	103	7	soon	soon	ADV
ct-12609	103	8	as	as	ADP
ct-12609	103	9	possible	possible	ADJ
ct-12609	103	10	(	(	PUNCT
ct-12609	103	11	within	within	ADP
ct-12609	103	12	30	30	NUM
ct-12609	103	13	to	to	PART
ct-12609	103	14	60	60	NUM
ct-12609	103	15	min	min	NOUN
ct-12609	103	16	)	)	PUNCT
ct-12609	103	17	and	and	CCONJ
ct-12609	103	18	the	the	DET
ct-12609	103	19	plasma	plasma	NOUN
ct-12609	103	20	transferred	transfer	VERB
ct-12609	103	21	immediately	immediately	ADV
ct-12609	103	22	to	to	ADP
ct-12609	103	23	a	a	DET
ct-12609	103	24	plastic	plastic	ADJ
ct-12609	103	25	tube	tube	NOUN
ct-12609	103	26	for	for	ADP
ct-12609	103	27	freezing	freezing	NOUN
ct-12609	103	28	and	and	CCONJ
ct-12609	103	29	shipping	shipping	NOUN
ct-12609	103	30	(	(	PUNCT
ct-12609	103	31	should	should	AUX
ct-12609	103	32	arrive	arrive	VERB
ct-12609	103	33	to	to	ADP
ct-12609	103	34	the	the	DET
ct-12609	103	35	laboratory	laboratory	NOUN
ct-12609	103	36	below	below	ADP
ct-12609	103	37	60	60	NUM
ct-12609	103	38	0f	0f	NOUN
ct-12609	103	39	)	)	PUNCT
ct-12609	103	40	.	.	PUNCT
ct-12609	104	1	this	this	DET
ct-12609	104	2	test	test	NOUN
ct-12609	104	3	is	be	AUX
ct-12609	104	4	recommended	recommend	VERB
ct-12609	104	5	when	when	SCONJ
ct-12609	104	6	one	one	PRON
ct-12609	104	7	is	be	AUX
ct-12609	104	8	trying	try	VERB
ct-12609	104	9	to	to	PART
ct-12609	104	10	avoid	avoid	VERB
ct-12609	104	11	administration	administration	NOUN
ct-12609	104	12	of	of	ADP
ct-12609	104	13	dexamethasone	dexamethasone	NOUN
ct-12609	104	14	to	to	ADP
ct-12609	104	15	laminitic	laminitic	ADJ
ct-12609	104	16	animals	animal	NOUN
ct-12609	104	17	.	.	PUNCT
ct-12609	105	1	insulin	insulin	NOUN
ct-12609	105	2	concentration	concentration	NOUN
ct-12609	105	3	.	.	PUNCT
ct-12609	106	1	insulin	insulin	NOUN
ct-12609	106	2	resistance	resistance	NOUN
ct-12609	106	3	/	/	SYM
ct-12609	106	4	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	106	5	has	have	AUX
ct-12609	106	6	been	be	AUX
ct-12609	106	7	recognized	recognize	VERB
ct-12609	106	8	in	in	ADP
ct-12609	106	9	horses	horse	NOUN
ct-12609	106	10	with	with	ADP
ct-12609	106	11	ppid	ppid	NOUN
ct-12609	106	12	.	.	PUNCT
ct-12609	107	1	affected	affect	VERB
ct-12609	107	2	horses	horse	NOUN
ct-12609	107	3	have	have	AUX
ct-12609	107	4	increased	increase	VERB
ct-12609	107	5	insulin	insulin	NOUN
ct-12609	107	6	blood	blood	NOUN
ct-12609	107	7	levels	level	NOUN
ct-12609	107	8	attributed	attribute	VERB
ct-12609	107	9	to	to	ADP
ct-12609	107	10	excessive	excessive	ADJ
ct-12609	107	11	circulating	circulate	VERB
ct-12609	107	12	concentrations	concentration	NOUN
ct-12609	107	13	of	of	ADP
ct-12609	107	14	cortisol	cortisol	NOUN
ct-12609	107	15	since	since	SCONJ
ct-12609	107	16	they	they	PRON
ct-12609	107	17	have	have	VERB
ct-12609	107	18	antagonistic	antagonistic	ADJ
ct-12609	107	19	metabolic	metabolic	NOUN
ct-12609	107	20	effects	effect	NOUN
ct-12609	107	21	.	.	PUNCT
ct-12609	108	1	excessive	excessive	ADJ
ct-12609	108	2	insulin	insulin	NOUN
ct-12609	108	3	concentrations	concentration	NOUN
ct-12609	108	4	vary	vary	VERB
ct-12609	108	5	between	between	ADP
ct-12609	108	6	laboratories	laboratory	NOUN
ct-12609	108	7	and	and	CCONJ
ct-12609	108	8	reference	reference	NOUN
ct-12609	108	9	values	value	NOUN
ct-12609	108	10	must	must	AUX
ct-12609	108	11	always	always	ADV
ct-12609	108	12	be	be	AUX
ct-12609	108	13	consulted	consult	VERB
ct-12609	108	14	when	when	SCONJ
ct-12609	108	15	interpreting	interpret	VERB
ct-12609	108	16	the	the	DET
ct-12609	108	17	test	test	NOUN
ct-12609	108	18	.	.	PUNCT
ct-12609	109	1	cutoff	cutoff	NOUN
ct-12609	109	2	point	point	NOUN
ct-12609	109	3	for	for	ADP
ct-12609	109	4	normal	normal	ADJ
ct-12609	109	5	insulin	insulin	NOUN
ct-12609	109	6	concentration	concentration	NOUN
ct-12609	109	7	varies	vary	VERB
ct-12609	109	8	from	from	ADP
ct-12609	109	9	25	25	NUM
ct-12609	109	10	µu	µu	NUM
ct-12609	109	11	/	/	SYM
ct-12609	109	12	ml	ml	NOUN
ct-12609	109	13	to	to	ADP
ct-12609	109	14	57	57	NUM
ct-12609	109	15	494	494	NUM
ct-12609	109	16	µu	µu	ADJ
ct-12609	109	17	/	/	SYM
ct-12609	109	18	ml7,10	ml7,10	NOUN
ct-12609	109	19	however	however	ADV
ct-12609	109	20	,	,	PUNCT
ct-12609	109	21	>	>	X
ct-12609	109	22	30	30	NUM
ct-12609	109	23	µu	µu	NUM
ct-12609	109	24	/	/	SYM
ct-12609	109	25	ml	ml	NOUN
ct-12609	109	26	is	be	AUX
ct-12609	109	27	considered	consider	VERB
ct-12609	109	28	diagnostic	diagnostic	ADJ
ct-12609	109	29	of	of	ADP
ct-12609	109	30	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	109	31	.	.	PUNCT
ct-12609	110	1	the	the	DET
ct-12609	110	2	accuracy	accuracy	NOUN
ct-12609	110	3	of	of	ADP
ct-12609	110	4	this	this	DET
ct-12609	110	5	test	test	NOUN
ct-12609	110	6	compared	compare	VERB
ct-12609	110	7	to	to	ADP
ct-12609	110	8	histological	histological	ADJ
ct-12609	110	9	findings	finding	NOUN
ct-12609	110	10	is	be	AUX
ct-12609	110	11	92	92	NUM
ct-12609	110	12	%	%	NOUN
ct-12609	110	13	.	.	PUNCT
ct-12609	111	1	this	this	DET
ct-12609	111	2	test	test	NOUN
ct-12609	111	3	has	have	VERB
ct-12609	111	4	the	the	DET
ct-12609	111	5	advantage	advantage	NOUN
ct-12609	111	6	of	of	ADP
ct-12609	111	7	a	a	DET
ct-12609	111	8	single	single	ADJ
ct-12609	111	9	sample	sample	NOUN
ct-12609	111	10	for	for	ADP
ct-12609	111	11	the	the	DET
ct-12609	111	12	diagnosis	diagnosis	NOUN
ct-12609	111	13	,	,	PUNCT
ct-12609	111	14	however	however	ADV
ct-12609	111	15	,	,	PUNCT
ct-12609	111	16	ms	ms	PROPN
ct-12609	111	17	should	should	AUX
ct-12609	111	18	be	be	AUX
ct-12609	111	19	ruled	rule	VERB
ct-12609	111	20	out	out	ADP
ct-12609	111	21	since	since	SCONJ
ct-12609	111	22	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	111	23	is	be	AUX
ct-12609	111	24	also	also	ADV
ct-12609	111	25	present	present	ADJ
ct-12609	111	26	in	in	ADP
ct-12609	111	27	this	this	DET
ct-12609	111	28	condition	condition	NOUN
ct-12609	111	29	.	.	PUNCT
ct-12609	112	1	douglas	douglas	PROPN
ct-12609	112	2	has	have	AUX
ct-12609	112	3	proposed	propose	VERB
ct-12609	112	4	that	that	SCONJ
ct-12609	112	5	testing	testing	NOUN
ct-12609	112	6	for	for	ADP
ct-12609	112	7	suspected	suspect	VERB
ct-12609	112	8	cases	case	NOUN
ct-12609	112	9	of	of	ADP
ct-12609	112	10	ppid	ppid	NOUN
ct-12609	112	11	and	and	CCONJ
ct-12609	112	12	ms	ms	PROPN
ct-12609	112	13	should	should	AUX
ct-12609	112	14	start	start	VERB
ct-12609	112	15	by	by	ADP
ct-12609	112	16	simply	simply	ADV
ct-12609	112	17	collecting	collect	VERB
ct-12609	112	18	two	two	NUM
ct-12609	112	19	serum	serum	NOUN
ct-12609	112	20	samples	sample	NOUN
ct-12609	112	21	8	8	NUM
ct-12609	112	22	to	to	PART
ct-12609	112	23	10	10	NUM
ct-12609	112	24	h	h	NOUN
ct-12609	112	25	apart.7	apart.7	ADP
ct-12609	113	1	no	no	DET
ct-12609	113	2	grain	grain	NOUN
ct-12609	113	3	should	should	AUX
ct-12609	113	4	be	be	AUX
ct-12609	113	5	given	give	VERB
ct-12609	113	6	4	4	NUM
ct-12609	113	7	h	h	NOUN
ct-12609	113	8	before	before	SCONJ
ct-12609	113	9	both	both	CCONJ
ct-12609	113	10	samples	sample	NOUN
ct-12609	113	11	and	and	CCONJ
ct-12609	113	12	stress	stress	NOUN
ct-12609	113	13	should	should	AUX
ct-12609	113	14	be	be	AUX
ct-12609	113	15	avoided	avoid	VERB
ct-12609	113	16	since	since	SCONJ
ct-12609	113	17	both	both	DET
ct-12609	113	18	parameters	parameter	NOUN
ct-12609	113	19	can	can	AUX
ct-12609	113	20	result	result	VERB
ct-12609	113	21	in	in	ADP
ct-12609	113	22	false	false	ADJ
ct-12609	113	23	positives	positive	NOUN
ct-12609	113	24	.	.	PUNCT
ct-12609	114	1	serum	serum	NOUN
ct-12609	114	2	samples	sample	NOUN
ct-12609	114	3	are	be	AUX
ct-12609	114	4	collected	collect	VERB
ct-12609	114	5	for	for	ADP
ct-12609	114	6	measurement	measurement	NOUN
ct-12609	114	7	of	of	ADP
ct-12609	114	8	cortisol	cortisol	NOUN
ct-12609	114	9	,	,	PUNCT
ct-12609	114	10	insulin	insulin	NOUN
ct-12609	114	11	and	and	CCONJ
ct-12609	114	12	thyroxine	thyroxine	NOUN
ct-12609	114	13	(	(	PUNCT
ct-12609	114	14	tt4	tt4	PROPN
ct-12609	114	15	)	)	PUNCT
ct-12609	114	16	.	.	PUNCT
ct-12609	115	1	the	the	DET
ct-12609	115	2	absolute	absolute	ADJ
ct-12609	115	3	values	value	NOUN
ct-12609	115	4	of	of	ADP
ct-12609	115	5	cortisol	cortisol	NOUN
ct-12609	115	6	are	be	AUX
ct-12609	115	7	20	20	NUM
ct-12609	115	8	to	to	PART
ct-12609	115	9	90	90	NUM
ct-12609	115	10	ng	ng	NOUN
ct-12609	115	11	/	/	SYM
ct-12609	115	12	ml	ml	PROPN
ct-12609	115	13	,	,	PUNCT
ct-12609	115	14	however	however	ADV
ct-12609	115	15	,	,	PUNCT
ct-12609	115	16	the	the	DET
ct-12609	115	17	test	test	NOUN
ct-12609	115	18	specifically	specifically	ADV
ct-12609	115	19	looks	look	VERB
ct-12609	115	20	at	at	ADP
ct-12609	115	21	a	a	DET
ct-12609	115	22	difference	difference	NOUN
ct-12609	115	23	of	of	ADP
ct-12609	115	24	less	less	ADJ
ct-12609	115	25	than	than	ADP
ct-12609	115	26	30	30	NUM
ct-12609	115	27	%	%	NOUN
ct-12609	115	28	between	between	ADP
ct-12609	115	29	the	the	DET
ct-12609	115	30	two	two	NUM
ct-12609	115	31	samples	sample	NOUN
ct-12609	115	32	since	since	SCONJ
ct-12609	115	33	that	that	PRON
ct-12609	115	34	indicates	indicate	VERB
ct-12609	115	35	a	a	DET
ct-12609	115	36	loss	loss	NOUN
ct-12609	115	37	in	in	ADP
ct-12609	115	38	the	the	DET
ct-12609	115	39	diurnal	diurnal	ADJ
ct-12609	115	40	cortisol	cortisol	ADJ
ct-12609	115	41	rhythm	rhythm	NOUN
ct-12609	115	42	which	which	PRON
ct-12609	115	43	is	be	AUX
ct-12609	115	44	considered	consider	VERB
ct-12609	115	45	suggestive	suggestive	ADJ
ct-12609	115	46	of	of	ADP
ct-12609	115	47	ppid	ppid	NOUN
ct-12609	115	48	.	.	PUNCT
ct-12609	116	1	a	a	DET
ct-12609	116	2	consistent	consistent	ADJ
ct-12609	116	3	insulin	insulin	NOUN
ct-12609	116	4	value	value	NOUN
ct-12609	116	5	>	>	X
ct-12609	116	6	25	25	NUM
ct-12609	116	7	to	to	PART
ct-12609	116	8	30	30	NUM
ct-12609	116	9	µu	µu	NUM
ct-12609	116	10	/	/	SYM
ct-12609	116	11	ml	ml	NOUN
ct-12609	116	12	will	will	AUX
ct-12609	116	13	be	be	AUX
ct-12609	116	14	indicative	indicative	ADJ
ct-12609	116	15	of	of	ADP
ct-12609	116	16	ir	ir	PROPN
ct-12609	116	17	.	.	PUNCT
ct-12609	117	1	a	a	DET
ct-12609	117	2	typical	typical	ADJ
ct-12609	117	3	endocrine	endocrine	NOUN
ct-12609	117	4	profile	profile	NOUN
ct-12609	117	5	in	in	ADP
ct-12609	117	6	a	a	DET
ct-12609	117	7	horse	horse	NOUN
ct-12609	117	8	with	with	ADP
ct-12609	117	9	ir	ir	PROPN
ct-12609	117	10	and	and	CCONJ
ct-12609	117	11	ppid	ppid	PROPN
ct-12609	117	12	sample	sample	NOUN
ct-12609	117	13	time	time	NOUN
ct-12609	117	14	tt4	tt4	PROPN
ct-12609	117	15	normal=12.0	normal=12.0	PROPN
ct-12609	117	16	ng	ng	PROPN
ct-12609	117	17	/	/	SYM
ct-12609	117	18	ml	ml	NOUN
ct-12609	117	19	insulin	insulin	NOUN
ct-12609	117	20	normal=<25	normal=<25	NOUN
ct-12609	117	21	μu	μu	NOUN
ct-12609	117	22	/	/	SYM
ct-12609	117	23	ml	ml	NOUN
ct-12609	117	24	cortisol	cortisol	ADJ
ct-12609	117	25	normal	normal	ADJ
ct-12609	117	26	20	20	NUM
ct-12609	117	27	-	-	SYM
ct-12609	117	28	90	90	NUM
ct-12609	117	29	ng	ng	PROPN
ct-12609	117	30	/	/	SYM
ct-12609	117	31	ml	ml	NOUN
ct-12609	117	32	cortisol	cortisol	NOUN
ct-12609	117	33	normal>30	normal>30	ADV
ct-12609	117	34	%	%	NOUN
ct-12609	117	35	difference	difference	NOUN
ct-12609	117	36	8	8	NUM
ct-12609	117	37	to	to	PART
ct-12609	117	38	10	10	NUM
ct-12609	117	39	am	be	AUX
ct-12609	117	40	11.9	11.9	NUM
ct-12609	117	41	ng	ng	NOUN
ct-12609	117	42	/	/	SYM
ct-12609	117	43	ml	ml	PROPN
ct-12609	117	44	35	35	NUM
ct-12609	117	45	μu	μu	NOUN
ct-12609	117	46	/	/	SYM
ct-12609	117	47	ml	ml	PROPN
ct-12609	117	48	58	58	NUM
ct-12609	117	49	ng	ng	NOUN
ct-12609	117	50	/	/	SYM
ct-12609	117	51	ml	ml	PROPN
ct-12609	117	52	11	11	NUM
ct-12609	117	53	%	%	NOUN
ct-12609	117	54	4	4	NUM
ct-12609	117	55	to	to	PART
ct-12609	117	56	6	6	NUM
ct-12609	117	57	pm	pm	NOUN
ct-12609	117	58	12.2	12.2	NUM
ct-12609	117	59	ng	ng	NOUN
ct-12609	117	60	/	/	SYM
ct-12609	117	61	ml	ml	PROPN
ct-12609	117	62	55	55	NUM
ct-12609	117	63	μu	μu	NOUN
ct-12609	117	64	/	/	SYM
ct-12609	117	65	ml	ml	PROPN
ct-12609	117	66	65	65	NUM
ct-12609	117	67	ng	ng	NOUN
ct-12609	117	68	/	/	SYM
ct-12609	117	69	ml	ml	NOUN
ct-12609	117	70	from	from	ADP
ct-12609	117	71	:	:	PUNCT
ct-12609	117	72	douglas	douglas	PROPN
ct-12609	117	73	rh	rh	PROPN
ct-12609	117	74	.	.	PROPN
ct-12609	117	75	endocrine	endocrine	PROPN
ct-12609	117	76	assessment	assessment	NOUN
ct-12609	117	77	and	and	CCONJ
ct-12609	117	78	management	management	NOUN
ct-12609	117	79	of	of	ADP
ct-12609	117	80	insulin	insulin	NOUN
ct-12609	117	81	resistance	resistance	NOUN
ct-12609	117	82	and	and	CCONJ
ct-12609	117	83	ppid.7	ppid.7	NUM
ct-12609	117	84	495	495	NUM
ct-12609	117	85	horses	horse	NOUN
ct-12609	117	86	suspected	suspect	VERB
ct-12609	117	87	of	of	ADP
ct-12609	117	88	having	have	VERB
ct-12609	117	89	early	early	ADJ
ct-12609	117	90	signs	sign	NOUN
ct-12609	117	91	of	of	ADP
ct-12609	117	92	ppid	ppid	NOUN
ct-12609	117	93	(	(	PUNCT
ct-12609	117	94	“	"	PUNCT
ct-12609	117	95	pre	pre	ADJ
ct-12609	117	96	-	-	NOUN
ct-12609	117	97	cushingoid	cushingoid	NOUN
ct-12609	117	98	”	"	PUNCT
ct-12609	117	99	)	)	PUNCT
ct-12609	117	100	that	that	PRON
ct-12609	117	101	have	have	VERB
ct-12609	117	102	normal	normal	ADJ
ct-12609	117	103	values	value	NOUN
ct-12609	117	104	from	from	ADP
ct-12609	117	105	earlier	early	ADJ
ct-12609	117	106	,	,	PUNCT
ct-12609	117	107	appropriate	appropriate	ADJ
ct-12609	117	108	diagnostic	diagnostic	ADJ
ct-12609	117	109	tests	test	NOUN
ct-12609	117	110	,	,	PUNCT
ct-12609	117	111	should	should	AUX
ct-12609	117	112	be	be	AUX
ct-12609	117	113	re	re	VERB
ct-12609	117	114	-	-	VERB
ct-12609	117	115	tested	test	VERB
ct-12609	117	116	at	at	ADP
ct-12609	117	117	4	4	NUM
ct-12609	117	118	to	to	PART
ct-12609	117	119	6	6	NUM
ct-12609	117	120	month	month	NOUN
ct-12609	117	121	intervals	interval	NOUN
ct-12609	117	122	avoiding	avoid	VERB
ct-12609	117	123	the	the	DET
ct-12609	117	124	fall	fall	NOUN
ct-12609	117	125	months	month	NOUN
ct-12609	117	126	.	.	PUNCT
ct-12609	118	1	the	the	DET
ct-12609	118	2	evaluation	evaluation	NOUN
ct-12609	118	3	should	should	AUX
ct-12609	118	4	include	include	VERB
ct-12609	118	5	a	a	DET
ct-12609	118	6	physical	physical	ADJ
ct-12609	118	7	examination	examination	NOUN
ct-12609	118	8	,	,	PUNCT
ct-12609	118	9	cbc	cbc	PROPN
ct-12609	118	10	,	,	PUNCT
ct-12609	118	11	serum	serum	NOUN
ct-12609	118	12	chemistry	chemistry	NOUN
ct-12609	118	13	,	,	PUNCT
ct-12609	118	14	acth	acth	NOUN
ct-12609	118	15	,	,	PUNCT
ct-12609	118	16	insulin	insulin	NOUN
ct-12609	118	17	concentrations	concentration	NOUN
ct-12609	118	18	and	and	CCONJ
ct-12609	118	19	dst	dst	NOUN
ct-12609	118	20	as	as	ADP
ct-12609	118	21	a	a	DET
ct-12609	118	22	baseline	baseline	NOUN
ct-12609	118	23	profile.10	profile.10	NOUN
ct-12609	118	24	treatment	treatment	NOUN
ct-12609	118	25	management	management	NOUN
ct-12609	118	26	of	of	ADP
ct-12609	118	27	ppid	ppid	NOUN
ct-12609	118	28	is	be	AUX
ct-12609	118	29	essential	essential	ADJ
ct-12609	118	30	to	to	PART
ct-12609	118	31	assure	assure	VERB
ct-12609	118	32	appropriate	appropriate	ADJ
ct-12609	118	33	health	health	NOUN
ct-12609	118	34	care	care	NOUN
ct-12609	118	35	of	of	ADP
ct-12609	118	36	older	old	ADJ
ct-12609	118	37	animals	animal	NOUN
ct-12609	118	38	:	:	PUNCT
ct-12609	118	39	body	body	NOUN
ct-12609	118	40	clipping	clip	VERB
ct-12609	118	41	,	,	PUNCT
ct-12609	118	42	regular	regular	ADJ
ct-12609	118	43	hoof	hoof	NOUN
ct-12609	118	44	and	and	CCONJ
ct-12609	118	45	dental	dental	ADJ
ct-12609	118	46	care	care	NOUN
ct-12609	118	47	,	,	PUNCT
ct-12609	118	48	enhanced	enhanced	ADJ
ct-12609	118	49	nutrition	nutrition	NOUN
ct-12609	118	50	,	,	PUNCT
ct-12609	118	51	and	and	CCONJ
ct-12609	118	52	intermittent	intermittent	ADJ
ct-12609	118	53	or	or	CCONJ
ct-12609	118	54	long	long	ADJ
ct-12609	118	55	term	term	NOUN
ct-12609	118	56	antibiotics	antibiotic	NOUN
ct-12609	118	57	may	may	AUX
ct-12609	118	58	be	be	AUX
ct-12609	118	59	required	require	VERB
ct-12609	118	60	.	.	PUNCT
ct-12609	119	1	the	the	DET
ct-12609	119	2	dopamine	dopamine	NOUN
ct-12609	119	3	agonist	agonist	NOUN
ct-12609	119	4	,	,	PUNCT
ct-12609	119	5	pergolide	pergolide	NOUN
ct-12609	119	6	mesylate	mesylate	NOUN
ct-12609	119	7	(	(	PUNCT
ct-12609	119	8	1	1	NUM
ct-12609	119	9	to	to	PART
ct-12609	119	10	5	5	NUM
ct-12609	119	11	mg	mg	PROPN
ct-12609	119	12	/	/	SYM
ct-12609	119	13	po	po	NOUN
ct-12609	119	14	/	/	SYM
ct-12609	119	15	q	q	PROPN
ct-12609	119	16	24	24	NUM
ct-12609	119	17	h/500	h/500	PROPN
ct-12609	119	18	kg	kg	PROPN
ct-12609	119	19	horse	horse	NOUN
ct-12609	119	20	)	)	PUNCT
ct-12609	119	21	is	be	AUX
ct-12609	119	22	most	most	ADV
ct-12609	119	23	commonly	commonly	ADV
ct-12609	119	24	administered	administer	VERB
ct-12609	119	25	since	since	SCONJ
ct-12609	119	26	the	the	DET
ct-12609	119	27	disease	disease	NOUN
ct-12609	119	28	appears	appear	VERB
ct-12609	119	29	to	to	PART
ct-12609	119	30	be	be	AUX
ct-12609	119	31	associated	associate	VERB
ct-12609	119	32	with	with	ADP
ct-12609	119	33	a	a	DET
ct-12609	119	34	loss	loss	NOUN
ct-12609	119	35	of	of	ADP
ct-12609	119	36	hypothalamic	hypothalamic	ADJ
ct-12609	119	37	dopaminergic	dopaminergic	ADJ
ct-12609	119	38	innervations	innervation	NOUN
ct-12609	119	39	.	.	PUNCT
ct-12609	120	1	pergolide	pergolide	NOUN
ct-12609	120	2	should	should	AUX
ct-12609	120	3	be	be	AUX
ct-12609	120	4	discontinued	discontinue	VERB
ct-12609	120	5	in	in	ADP
ct-12609	120	6	pregnant	pregnant	ADJ
ct-12609	120	7	mares	mare	NOUN
ct-12609	120	8	approximately	approximately	ADV
ct-12609	120	9	3	3	NUM
ct-12609	120	10	weeks	week	NOUN
ct-12609	120	11	before	before	SCONJ
ct-12609	120	12	their	their	PRON
ct-12609	120	13	anticipated	anticipate	VERB
ct-12609	120	14	foaling	foaling	NOUN
ct-12609	120	15	date	date	NOUN
ct-12609	120	16	to	to	PART
ct-12609	120	17	avoid	avoid	VERB
ct-12609	120	18	agalactia	agalactia	PROPN
ct-12609	120	19	(	(	PUNCT
ct-12609	120	20	prl	prl	NOUN
ct-12609	120	21	suppression	suppression	NOUN
ct-12609	120	22	)	)	PUNCT
ct-12609	120	23	.	.	PUNCT
ct-12609	121	1	the	the	DET
ct-12609	121	2	most	most	ADV
ct-12609	121	3	common	common	ADJ
ct-12609	121	4	adverse	adverse	ADJ
ct-12609	121	5	effect	effect	NOUN
ct-12609	121	6	of	of	ADP
ct-12609	121	7	pergolide	pergolide	NOUN
ct-12609	121	8	administration	administration	NOUN
ct-12609	121	9	is	be	AUX
ct-12609	121	10	a	a	DET
ct-12609	121	11	mild	mild	ADJ
ct-12609	121	12	decrease	decrease	NOUN
ct-12609	121	13	in	in	ADP
ct-12609	121	14	appetite	appetite	NOUN
ct-12609	121	15	.	.	PUNCT
ct-12609	122	1	serotonin	serotonin	NOUN
ct-12609	122	2	antagonists	antagonist	NOUN
ct-12609	122	3	(	(	PUNCT
ct-12609	122	4	cyproheptadine	cyproheptadine	NOUN
ct-12609	122	5	0.25	0.25	NUM
ct-12609	122	6	mg	mg	PROPN
ct-12609	122	7	/	/	SYM
ct-12609	122	8	kg	kg	PROPN
ct-12609	122	9	/	/	SYM
ct-12609	122	10	po	po	NOUN
ct-12609	122	11	/	/	SYM
ct-12609	122	12	q	q	PROPN
ct-12609	122	13	12	12	NUM
ct-12609	122	14	or	or	CCONJ
ct-12609	122	15	24	24	NUM
ct-12609	122	16	h	h	NOUN
ct-12609	122	17	,	,	PUNCT
ct-12609	122	18	or	or	CCONJ
ct-12609	122	19	200	200	NUM
ct-12609	122	20	to	to	PART
ct-12609	122	21	400	400	NUM
ct-12609	122	22	mg/500	mg/500	NUM
ct-12609	122	23	kg	kg	NOUN
ct-12609	122	24	/	/	SYM
ct-12609	122	25	po	po	NOUN
ct-12609	122	26	/	/	SYM
ct-12609	122	27	q	q	PROPN
ct-12609	122	28	24	24	NUM
ct-12609	122	29	h	h	NOUN
ct-12609	122	30	)	)	PUNCT
ct-12609	122	31	are	be	AUX
ct-12609	122	32	also	also	ADV
ct-12609	122	33	used	use	VERB
ct-12609	122	34	alone	alone	ADV
ct-12609	122	35	or	or	CCONJ
ct-12609	122	36	in	in	ADP
ct-12609	122	37	conjunction	conjunction	NOUN
ct-12609	122	38	with	with	ADP
ct-12609	122	39	pergolide	pergolide	NOUN
ct-12609	122	40	.	.	PUNCT
ct-12609	123	1	this	this	DET
ct-12609	123	2	therapy	therapy	NOUN
ct-12609	123	3	is	be	AUX
ct-12609	123	4	based	base	VERB
ct-12609	123	5	on	on	ADP
ct-12609	123	6	the	the	DET
ct-12609	123	7	secretagogue	secretagogue	NOUN
ct-12609	123	8	effect	effect	NOUN
ct-12609	123	9	of	of	ADP
ct-12609	123	10	serotonin	serotonin	VERB
ct-12609	123	11	on	on	ADP
ct-12609	123	12	acth	acth	NOUN
ct-12609	123	13	in	in	ADP
ct-12609	123	14	rat	rat	NOUN
ct-12609	123	15	pars	par	NOUN
ct-12609	123	16	intermedia.10,17	intermedia.10,17	VERB
ct-12609	123	17	the	the	DET
ct-12609	123	18	use	use	NOUN
ct-12609	123	19	of	of	ADP
ct-12609	123	20	cyproheptadine	cyproheptadine	NOUN
ct-12609	123	21	is	be	AUX
ct-12609	123	22	controversial	controversial	ADJ
ct-12609	123	23	since	since	SCONJ
ct-12609	123	24	results	result	NOUN
ct-12609	123	25	appear	appear	VERB
ct-12609	123	26	to	to	PART
ct-12609	123	27	be	be	AUX
ct-12609	123	28	similar	similar	ADJ
ct-12609	123	29	to	to	ADP
ct-12609	123	30	the	the	DET
ct-12609	123	31	clinical	clinical	ADJ
ct-12609	123	32	improvement	improvement	NOUN
ct-12609	123	33	obtained	obtain	VERB
ct-12609	123	34	with	with	ADP
ct-12609	123	35	good	good	ADJ
ct-12609	123	36	management	management	NOUN
ct-12609	123	37	alone	alone	ADV
ct-12609	123	38	.	.	PUNCT
ct-12609	124	1	it	it	PRON
ct-12609	124	2	has	have	AUX
ct-12609	124	3	been	be	AUX
ct-12609	124	4	suggested	suggest	VERB
ct-12609	124	5	,	,	PUNCT
ct-12609	124	6	that	that	SCONJ
ct-12609	124	7	a	a	DET
ct-12609	124	8	combination	combination	NOUN
ct-12609	124	9	of	of	ADP
ct-12609	124	10	1	1	NUM
ct-12609	124	11	mg	mg	NOUN
ct-12609	124	12	of	of	ADP
ct-12609	124	13	pergolide	pergolide	NOUN
ct-12609	124	14	and	and	CCONJ
ct-12609	124	15	200	200	NUM
ct-12609	124	16	mg	mg	NOUN
ct-12609	124	17	of	of	ADP
ct-12609	124	18	cyproheptadine	cyproheptadine	NOUN
ct-12609	124	19	/	/	SYM
ct-12609	124	20	day	day	NOUN
ct-12609	124	21	accelerates	accelerate	VERB
ct-12609	124	22	the	the	DET
ct-12609	124	23	clinical	clinical	ADJ
ct-12609	124	24	response	response	NOUN
ct-12609	124	25	to	to	ADP
ct-12609	124	26	medication	medication	NOUN
ct-12609	124	27	,	,	PUNCT
ct-12609	124	28	increasing	increase	VERB
ct-12609	124	29	the	the	DET
ct-12609	124	30	chances	chance	NOUN
ct-12609	124	31	of	of	ADP
ct-12609	124	32	successfully	successfully	ADV
ct-12609	124	33	breeding	breed	VERB
ct-12609	124	34	a	a	DET
ct-12609	124	35	mare	mare	NOUN
ct-12609	124	36	with	with	ADP
ct-12609	124	37	history	history	NOUN
ct-12609	124	38	of	of	ADP
ct-12609	124	39	development	development	NOUN
ct-12609	124	40	of	of	ADP
ct-12609	124	41	anovulatory	anovulatory	NOUN
ct-12609	124	42	follicles	follicle	NOUN
ct-12609	124	43	or	or	CCONJ
ct-12609	124	44	chronic	chronic	ADJ
ct-12609	124	45	endometritis.6	endometritis.6	PROPN
ct-12609	124	46	recent	recent	ADJ
ct-12609	124	47	studies	study	NOUN
ct-12609	124	48	have	have	AUX
ct-12609	124	49	examined	examine	VERB
ct-12609	124	50	the	the	DET
ct-12609	124	51	use	use	NOUN
ct-12609	124	52	of	of	ADP
ct-12609	124	53	trilostane	trilostane	NOUN
ct-12609	124	54	(	(	PUNCT
ct-12609	124	55	0.4	0.4	NUM
ct-12609	124	56	to	to	PART
ct-12609	124	57	1.0	1.0	NUM
ct-12609	124	58	mg	mg	PROPN
ct-12609	124	59	/	/	SYM
ct-12609	124	60	kg	kg	PROPN
ct-12609	124	61	/	/	SYM
ct-12609	124	62	q	q	PROPN
ct-12609	124	63	24	24	NUM
ct-12609	124	64	h	h	NOUN
ct-12609	124	65	in	in	ADP
ct-12609	124	66	feed	feed	NOUN
ct-12609	124	67	)	)	PUNCT
ct-12609	124	68	in	in	ADP
ct-12609	124	69	horses	horse	NOUN
ct-12609	124	70	with	with	ADP
ct-12609	124	71	ppid.10,18	ppid.10,18	NOUN
ct-12609	124	72	this	this	DET
ct-12609	124	73	drug	drug	NOUN
ct-12609	124	74	is	be	AUX
ct-12609	124	75	a	a	DET
ct-12609	124	76	competitive	competitive	ADJ
ct-12609	124	77	inhibitor	inhibitor	NOUN
ct-12609	124	78	of	of	ADP
ct-12609	124	79	3	3	NUM
ct-12609	124	80	-	-	PUNCT
ct-12609	124	81	ß	ß	PRON
ct-12609	124	82	hydroxysteroid	hydroxysteroid	NOUN
ct-12609	124	83	dehydrogenase	dehydrogenase	NOUN
ct-12609	124	84	,	,	PUNCT
ct-12609	124	85	496	496	NUM
ct-12609	124	86	an	an	DET
ct-12609	124	87	adrenocortical	adrenocortical	ADJ
ct-12609	124	88	enzyme	enzyme	NOUN
ct-12609	124	89	needed	need	VERB
ct-12609	124	90	for	for	ADP
ct-12609	124	91	cortisol	cortisol	ADJ
ct-12609	124	92	production	production	NOUN
ct-12609	124	93	.	.	PUNCT
ct-12609	125	1	even	even	ADV
ct-12609	125	2	though	though	SCONJ
ct-12609	125	3	some	some	DET
ct-12609	125	4	treated	treat	VERB
ct-12609	125	5	horses	horse	NOUN
ct-12609	125	6	exhibited	exhibit	VERB
ct-12609	125	7	a	a	DET
ct-12609	125	8	decrease	decrease	NOUN
ct-12609	125	9	in	in	ADP
ct-12609	125	10	clinical	clinical	ADJ
ct-12609	125	11	signs	sign	NOUN
ct-12609	125	12	,	,	PUNCT
ct-12609	125	13	there	there	PRON
ct-12609	125	14	is	be	VERB
ct-12609	125	15	reservation	reservation	NOUN
ct-12609	125	16	toward	toward	ADP
ct-12609	125	17	using	use	VERB
ct-12609	125	18	this	this	DET
ct-12609	125	19	treatment	treatment	NOUN
ct-12609	125	20	because	because	SCONJ
ct-12609	125	21	less	less	ADJ
ct-12609	125	22	than	than	ADP
ct-12609	125	23	20	20	NUM
ct-12609	125	24	%	%	NOUN
ct-12609	125	25	of	of	ADP
ct-12609	125	26	horses	horse	NOUN
ct-12609	125	27	with	with	ADP
ct-12609	125	28	ppid	ppid	PROPN
ct-12609	125	29	have	have	VERB
ct-12609	125	30	adrenocortical	adrenocortical	ADJ
ct-12609	125	31	hyperplasia	hyperplasia	NOUN
ct-12609	125	32	.	.	PUNCT
ct-12609	126	1	aging	aging	NOUN
ct-12609	126	2	,	,	PUNCT
ct-12609	126	3	obesity	obesity	NOUN
ct-12609	126	4	,	,	PUNCT
ct-12609	126	5	insulin	insulin	NOUN
ct-12609	126	6	resistance	resistance	NOUN
ct-12609	126	7	and	and	CCONJ
ct-12609	126	8	infertility	infertility	NOUN
ct-12609	126	9	recent	recent	ADJ
ct-12609	126	10	studies	study	NOUN
ct-12609	126	11	associate	associate	VERB
ct-12609	126	12	obesity	obesity	NOUN
ct-12609	126	13	and	and	CCONJ
ct-12609	126	14	insulin	insulin	NOUN
ct-12609	126	15	resistance	resistance	NOUN
ct-12609	126	16	in	in	ADP
ct-12609	126	17	horses	horse	NOUN
ct-12609	126	18	with	with	ADP
ct-12609	126	19	development	development	NOUN
ct-12609	126	20	of	of	ADP
ct-12609	126	21	abnormal	abnormal	ADJ
ct-12609	126	22	reproductive	reproductive	ADJ
ct-12609	126	23	function	function	NOUN
ct-12609	126	24	and	and	CCONJ
ct-12609	126	25	laminitis.19	laminitis.19	NOUN
ct-12609	126	26	equine	equine	NOUN
ct-12609	126	27	ms	ms	PROPN
ct-12609	126	28	and	and	CCONJ
ct-12609	126	29	cd	cd	PROPN
ct-12609	126	30	or	or	CCONJ
ct-12609	126	31	ppid	ppid	NOUN
ct-12609	126	32	share	share	NOUN
ct-12609	126	33	traits	trait	NOUN
ct-12609	126	34	that	that	PRON
ct-12609	126	35	provide	provide	VERB
ct-12609	126	36	plausible	plausible	ADJ
ct-12609	126	37	explanations	explanation	NOUN
ct-12609	126	38	for	for	ADP
ct-12609	126	39	the	the	DET
ct-12609	126	40	clinically	clinically	ADV
ct-12609	126	41	perceived	perceive	VERB
ct-12609	126	42	increased	increase	VERB
ct-12609	126	43	incidence	incidence	NOUN
ct-12609	126	44	of	of	ADP
ct-12609	126	45	fertility	fertility	NOUN
ct-12609	126	46	problems	problem	NOUN
ct-12609	126	47	in	in	ADP
ct-12609	126	48	horses	horse	NOUN
ct-12609	126	49	.	.	PUNCT
ct-12609	127	1	a	a	X
ct-12609	127	2	)	)	PUNCT
ct-12609	127	3	the	the	DET
ct-12609	127	4	shared	share	VERB
ct-12609	127	5	clinical	clinical	ADJ
ct-12609	127	6	manifestations	manifestation	NOUN
ct-12609	127	7	of	of	ADP
ct-12609	127	8	both	both	DET
ct-12609	127	9	diseases	disease	NOUN
ct-12609	127	10	are	be	AUX
ct-12609	127	11	:	:	PUNCT
ct-12609	127	12	aged	aged	ADJ
ct-12609	127	13	horse	horse	NOUN
ct-12609	127	14	,	,	PUNCT
ct-12609	127	15	obesity	obesity	NOUN
ct-12609	127	16	,	,	PUNCT
ct-12609	127	17	regional	regional	ADJ
ct-12609	127	18	subcutaneous	subcutaneous	ADJ
ct-12609	127	19	adiposity	adiposity	NOUN
ct-12609	127	20	(	(	PUNCT
ct-12609	127	21	neck	neck	NOUN
ct-12609	127	22	,	,	PUNCT
ct-12609	127	23	tail	tail	NOUN
ct-12609	127	24	head	head	NOUN
ct-12609	127	25	,	,	PUNCT
ct-12609	127	26	prepuce	prepuce	NOUN
ct-12609	127	27	)	)	PUNCT
ct-12609	127	28	,	,	PUNCT
ct-12609	127	29	a	a	DET
ct-12609	127	30	history	history	NOUN
ct-12609	127	31	,	,	PUNCT
ct-12609	127	32	presence	presence	NOUN
ct-12609	127	33	or	or	CCONJ
ct-12609	127	34	predisposition	predisposition	NOUN
ct-12609	127	35	for	for	ADP
ct-12609	127	36	laminitis	laminitis	NOUN
ct-12609	127	37	and/or	and/or	CCONJ
ct-12609	127	38	infertility	infertility	NOUN
ct-12609	127	39	.	.	PUNCT
ct-12609	128	1	b	b	X
ct-12609	128	2	)	)	PUNCT
ct-12609	128	3	the	the	DET
ct-12609	128	4	shared	share	VERB
ct-12609	128	5	metabolic	metabolic	NOUN
ct-12609	128	6	alterations	alteration	NOUN
ct-12609	128	7	include	include	VERB
ct-12609	128	8	:	:	PUNCT
ct-12609	128	9	increased	increase	VERB
ct-12609	128	10	insulin	insulin	NOUN
ct-12609	128	11	and	and	CCONJ
ct-12609	128	12	or	or	CCONJ
ct-12609	128	13	insulin	insulin	NOUN
ct-12609	128	14	resistance	resistance	NOUN
ct-12609	128	15	,	,	PUNCT
ct-12609	128	16	+	+	PROPN
ct-12609	128	17	/	/	SYM
ct-12609	128	18	_	_	NOUN
ct-12609	128	19	increased	increase	VERB
ct-12609	128	20	glucose	glucose	NOUN
ct-12609	128	21	(	(	PUNCT
ct-12609	128	22	and	and	CCONJ
ct-12609	128	23	in	in	ADP
ct-12609	128	24	some	some	DET
ct-12609	128	25	cases	case	NOUN
ct-12609	128	26	increased	increase	VERB
ct-12609	128	27	leptin	leptin	NOUN
ct-12609	128	28	and	and	CCONJ
ct-12609	128	29	“	"	PUNCT
ct-12609	128	30	leptin	leptin	NOUN
ct-12609	128	31	resistance	resistance	NOUN
ct-12609	128	32	”	"	PUNCT
ct-12609	128	33	,	,	PUNCT
ct-12609	128	34	cortisol	cortisol	NOUN
ct-12609	128	35	and	and	CCONJ
ct-12609	128	36	fatty	fatty	NOUN
ct-12609	128	37	acid	acid	NOUN
ct-12609	128	38	)	)	PUNCT
ct-12609	128	39	.	.	PUNCT
ct-12609	129	1	c	c	X
ct-12609	129	2	)	)	PUNCT
ct-12609	129	3	the	the	DET
ct-12609	129	4	shared	share	VERB
ct-12609	129	5	presence	presence	NOUN
ct-12609	129	6	of	of	ADP
ct-12609	129	7	excessive	excessive	ADJ
ct-12609	129	8	fat	fat	NOUN
ct-12609	129	9	,	,	PUNCT
ct-12609	129	10	in	in	ADP
ct-12609	129	11	the	the	DET
ct-12609	129	12	form	form	NOUN
ct-12609	129	13	of	of	ADP
ct-12609	129	14	obesity	obesity	NOUN
ct-12609	129	15	or	or	CCONJ
ct-12609	129	16	regional	regional	ADJ
ct-12609	129	17	adiposity	adiposity	NOUN
ct-12609	129	18	,	,	PUNCT
ct-12609	129	19	creates	create	VERB
ct-12609	129	20	at	at	ADP
ct-12609	129	21	the	the	DET
ct-12609	129	22	cellular	cellular	ADJ
ct-12609	129	23	-	-	PUNCT
ct-12609	129	24	molecular	molecular	ADJ
ct-12609	129	25	level	level	NOUN
ct-12609	129	26	an	an	DET
ct-12609	129	27	increase	increase	NOUN
ct-12609	129	28	in	in	ADP
ct-12609	129	29	“	"	PUNCT
ct-12609	129	30	adipocytokines	adipocytokine	NOUN
ct-12609	129	31	”	"	PUNCT
ct-12609	129	32	such	such	ADJ
ct-12609	129	33	as	as	ADP
ct-12609	129	34	tumor	tumor	NOUN
ct-12609	129	35	necrosis	necrosis	NOUN
ct-12609	129	36	factor	factor	NOUN
ct-12609	129	37	-	-	PUNCT
ct-12609	129	38	α	α	X
ct-12609	129	39	(	(	PUNCT
ct-12609	129	40	tnf	tnf	PROPN
ct-12609	129	41	-	-	PUNCT
ct-12609	129	42	α	α	NOUN
ct-12609	129	43	)	)	PUNCT
ct-12609	129	44	.	.	PUNCT
ct-12609	130	1	therefore	therefore	ADV
ct-12609	130	2	,	,	PUNCT
ct-12609	130	3	ppid	ppid	PROPN
ct-12609	130	4	and	and	CCONJ
ct-12609	130	5	ms	ms	PROPN
ct-12609	130	6	may	may	AUX
ct-12609	130	7	also	also	ADV
ct-12609	130	8	have	have	VERB
ct-12609	130	9	an	an	DET
ct-12609	130	10	increased	increase	VERB
ct-12609	130	11	level	level	NOUN
ct-12609	130	12	of	of	ADP
ct-12609	130	13	tnf	tnf	PROPN
ct-12609	130	14	-	-	PUNCT
ct-12609	130	15	α	α	PROPN
ct-12609	130	16	,	,	PUNCT
ct-12609	130	17	a	a	DET
ct-12609	130	18	pro	pro	ADJ
ct-12609	130	19	-	-	ADJ
ct-12609	130	20	inflammatory	inflammatory	ADJ
ct-12609	130	21	cytokine	cytokine	NOUN
ct-12609	130	22	which	which	PRON
ct-12609	130	23	inhibits	inhibit	VERB
ct-12609	130	24	the	the	DET
ct-12609	130	25	proper	proper	ADJ
ct-12609	130	26	function	function	NOUN
ct-12609	130	27	of	of	ADP
ct-12609	130	28	the	the	DET
ct-12609	130	29	insulin	insulin	NOUN
ct-12609	130	30	receptor	receptor	NOUN
ct-12609	130	31	.	.	PUNCT
ct-12609	131	1	increased	increase	VERB
ct-12609	131	2	fatty	fatty	NOUN
ct-12609	131	3	acids	acid	NOUN
ct-12609	131	4	impair	impair	VERB
ct-12609	131	5	glucose	glucose	NOUN
ct-12609	131	6	transport	transport	NOUN
ct-12609	131	7	through	through	ADP
ct-12609	131	8	the	the	DET
ct-12609	131	9	membrane	membrane	NOUN
ct-12609	131	10	.	.	PUNCT
ct-12609	132	1	increased	increase	VERB
ct-12609	132	2	11ßhydroxysteroid	11ßhydroxysteroid	NUM
ct-12609	132	3	dehydrogenase-1	dehydrogenase-1	PROPN
ct-12609	132	4	(	(	PUNCT
ct-12609	132	5	11ß	11ß	NUM
ct-12609	132	6	-	-	PUNCT
ct-12609	132	7	hsd1	hsd1	ADJ
ct-12609	132	8	)	)	PUNCT
ct-12609	132	9	converts	convert	VERB
ct-12609	132	10	cortisone	cortisone	NOUN
ct-12609	132	11	to	to	ADP
ct-12609	132	12	cortisol	cortisol	NOUN
ct-12609	132	13	generating	generate	VERB
ct-12609	132	14	more	more	ADJ
ct-12609	132	15	adipogenesis	adipogenesis	NOUN
ct-12609	132	16	and	and	CCONJ
ct-12609	132	17	ir.2	ir.2	VERB
ct-12609	132	18	497	497	NUM
ct-12609	132	19	similar	similar	ADJ
ct-12609	132	20	to	to	ADP
ct-12609	132	21	humans	human	NOUN
ct-12609	132	22	,	,	PUNCT
ct-12609	132	23	old	old	ADJ
ct-12609	132	24	horses	horse	NOUN
ct-12609	132	25	have	have	AUX
ct-12609	132	26	been	be	AUX
ct-12609	132	27	identified	identify	VERB
ct-12609	132	28	as	as	ADP
ct-12609	132	29	developing	develop	VERB
ct-12609	132	30	a	a	DET
ct-12609	132	31	condition	condition	NOUN
ct-12609	132	32	referred	refer	VERB
ct-12609	132	33	to	to	ADP
ct-12609	132	34	as	as	ADP
ct-12609	132	35	“	"	PUNCT
ct-12609	132	36	inflamm	inflamm	NOUN
ct-12609	132	37	-	-	PUNCT
ct-12609	132	38	aging	aging	NOUN
ct-12609	132	39	”	"	PUNCT
ct-12609	132	40	.	.	PUNCT
ct-12609	133	1	this	this	DET
ct-12609	133	2	condition	condition	NOUN
ct-12609	133	3	is	be	AUX
ct-12609	133	4	a	a	DET
ct-12609	133	5	persistent	persistent	ADJ
ct-12609	133	6	low	low	ADJ
ct-12609	133	7	grade	grade	NOUN
ct-12609	133	8	,	,	PUNCT
ct-12609	133	9	systemic	systemic	ADJ
ct-12609	133	10	,	,	PUNCT
ct-12609	133	11	chronic	chronic	ADJ
ct-12609	133	12	,	,	PUNCT
ct-12609	133	13	inflammation	inflammation	NOUN
ct-12609	133	14	caused	cause	VERB
ct-12609	133	15	by	by	ADP
ct-12609	133	16	an	an	DET
ct-12609	133	17	increased	increase	VERB
ct-12609	133	18	production	production	NOUN
ct-12609	133	19	of	of	ADP
ct-12609	133	20	serum	serum	NOUN
ct-12609	133	21	levels	level	NOUN
ct-12609	133	22	of	of	ADP
ct-12609	133	23	il-6	il-6	NUM
ct-12609	133	24	and	and	CCONJ
ct-12609	133	25	tnf	tnf	PROPN
ct-12609	133	26	-	-	PUNCT
ct-12609	133	27	α.20	α.20	PROPN
ct-12609	133	28	increased	increase	VERB
ct-12609	133	29	body	body	NOUN
ct-12609	133	30	fat	fat	NOUN
ct-12609	133	31	,	,	PUNCT
ct-12609	133	32	associated	associate	VERB
ct-12609	133	33	with	with	ADP
ct-12609	133	34	obesity	obesity	NOUN
ct-12609	133	35	,	,	PUNCT
ct-12609	133	36	may	may	AUX
ct-12609	133	37	be	be	AUX
ct-12609	133	38	a	a	DET
ct-12609	133	39	contributing	contribute	VERB
ct-12609	133	40	factor	factor	NOUN
ct-12609	133	41	since	since	SCONJ
ct-12609	133	42	adipose	adipose	ADJ
ct-12609	133	43	tissue	tissue	NOUN
ct-12609	133	44	leads	lead	VERB
ct-12609	133	45	to	to	ADP
ct-12609	133	46	increased	increase	VERB
ct-12609	133	47	production	production	NOUN
ct-12609	133	48	of	of	ADP
ct-12609	133	49	inflammatory	inflammatory	ADJ
ct-12609	133	50	cytokines.20,21	cytokines.20,21	NOUN
ct-12609	133	51	adams	adams	PROPN
ct-12609	133	52	et	et	PROPN
ct-12609	133	53	al	al	PROPN
ct-12609	133	54	,	,	PUNCT
ct-12609	133	55	showed	show	VERB
ct-12609	133	56	that	that	SCONJ
ct-12609	133	57	fat	fat	ADJ
ct-12609	133	58	,	,	PUNCT
ct-12609	133	59	old	old	ADJ
ct-12609	133	60	,	,	PUNCT
ct-12609	133	61	horses	horse	NOUN
ct-12609	133	62	between	between	ADP
ct-12609	133	63	20	20	NUM
ct-12609	133	64	and	and	CCONJ
ct-12609	133	65	28	28	NUM
ct-12609	133	66	years	year	NOUN
ct-12609	133	67	old	old	ADJ
ct-12609	133	68	,	,	PUNCT
ct-12609	133	69	had	have	VERB
ct-12609	133	70	greater	great	ADJ
ct-12609	133	71	mrna	mrna	NOUN
ct-12609	133	72	expression	expression	NOUN
ct-12609	133	73	of	of	ADP
ct-12609	133	74	tnf	tnf	PROPN
ct-12609	133	75	-	-	PUNCT
ct-12609	133	76	α	α	PROPN
ct-12609	133	77	and	and	CCONJ
ct-12609	133	78	inf	inf	NOUN
ct-12609	133	79	-	-	PUNCT
ct-12609	133	80	γ	γ	NOUN
ct-12609	133	81	from	from	ADP
ct-12609	133	82	lymphocytes	lymphocyte	NOUN
ct-12609	133	83	and	and	CCONJ
ct-12609	133	84	monocytes	monocyte	NOUN
ct-12609	133	85	and	and	CCONJ
ct-12609	133	86	had	have	VERB
ct-12609	133	87	higher	high	ADJ
ct-12609	133	88	serum	serum	NOUN
ct-12609	133	89	concentrations	concentration	NOUN
ct-12609	133	90	of	of	ADP
ct-12609	133	91	tnf	tnf	PROPN
ct-12609	133	92	-	-	PUNCT
ct-12609	133	93	α	α	NOUN
ct-12609	133	94	protein	protein	NOUN
ct-12609	133	95	than	than	ADP
ct-12609	133	96	thin	thin	ADJ
ct-12609	133	97	old	old	ADJ
ct-12609	133	98	horses.21	horses.21	PROPN
ct-12609	133	99	the	the	DET
ct-12609	133	100	impact	impact	NOUN
ct-12609	133	101	of	of	ADP
ct-12609	133	102	this	this	DET
ct-12609	133	103	increase	increase	NOUN
ct-12609	133	104	in	in	ADP
ct-12609	133	105	pro	pro	ADJ
ct-12609	133	106	-	-	ADJ
ct-12609	133	107	inflammatory	inflammatory	ADJ
ct-12609	133	108	cytokines	cytokine	NOUN
ct-12609	133	109	and	and	CCONJ
ct-12609	133	110	infertility	infertility	NOUN
ct-12609	133	111	is	be	AUX
ct-12609	133	112	unknown	unknown	ADJ
ct-12609	133	113	.	.	PUNCT
ct-12609	134	1	in	in	ADP
ct-12609	134	2	humans	human	NOUN
ct-12609	134	3	,	,	PUNCT
ct-12609	134	4	elevated	elevated	ADJ
ct-12609	134	5	tnf	tnf	PROPN
ct-12609	134	6	-	-	PUNCT
ct-12609	134	7	α	α	PROPN
ct-12609	134	8	plays	play	VERB
ct-12609	134	9	a	a	DET
ct-12609	134	10	direct	direct	ADJ
ct-12609	134	11	role	role	NOUN
ct-12609	134	12	in	in	ADP
ct-12609	134	13	the	the	DET
ct-12609	134	14	development	development	NOUN
ct-12609	134	15	of	of	ADP
ct-12609	134	16	obesity	obesity	NOUN
ct-12609	134	17	-	-	PUNCT
ct-12609	134	18	associated	associate	VERB
ct-12609	134	19	insulin	insulin	NOUN
ct-12609	134	20	resistance	resistance	NOUN
ct-12609	134	21	and	and	CCONJ
ct-12609	134	22	it	it	PRON
ct-12609	134	23	appears	appear	VERB
ct-12609	134	24	that	that	SCONJ
ct-12609	134	25	inflammation	inflammation	NOUN
ct-12609	134	26	may	may	AUX
ct-12609	134	27	be	be	AUX
ct-12609	134	28	a	a	DET
ct-12609	134	29	key	key	ADJ
ct-12609	134	30	link	link	NOUN
ct-12609	134	31	between	between	ADP
ct-12609	134	32	obesity	obesity	NOUN
ct-12609	134	33	and	and	CCONJ
ct-12609	134	34	ir	ir	PROPN
ct-12609	134	35	in	in	ADP
ct-12609	134	36	horses	horse	NOUN
ct-12609	134	37	as	as	ADP
ct-12609	134	38	well.19	well.19	NOUN
ct-12609	134	39	in	in	ADP
ct-12609	134	40	women	woman	NOUN
ct-12609	134	41	,	,	PUNCT
ct-12609	134	42	chronic	chronic	ADJ
ct-12609	134	43	insulin	insulin	NOUN
ct-12609	134	44	resistance	resistance	NOUN
ct-12609	134	45	and	and	CCONJ
ct-12609	134	46	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	134	47	are	be	AUX
ct-12609	134	48	associated	associate	VERB
ct-12609	134	49	with	with	ADP
ct-12609	134	50	increased	increase	VERB
ct-12609	134	51	duration	duration	NOUN
ct-12609	134	52	of	of	ADP
ct-12609	134	53	the	the	DET
ct-12609	134	54	follicular	follicular	ADJ
ct-12609	134	55	phase	phase	NOUN
ct-12609	134	56	of	of	ADP
ct-12609	134	57	the	the	DET
ct-12609	134	58	menstrual	menstrual	ADJ
ct-12609	134	59	cycle	cycle	NOUN
ct-12609	134	60	.	.	PUNCT
ct-12609	135	1	polycystic	polycystic	ADJ
ct-12609	135	2	ovarian	ovarian	ADJ
ct-12609	135	3	syndrome	syndrome	NOUN
ct-12609	135	4	(	(	PUNCT
ct-12609	135	5	pos	pos	NOUN
ct-12609	135	6	)	)	PUNCT
ct-12609	135	7	in	in	ADP
ct-12609	135	8	women	woman	NOUN
ct-12609	135	9	is	be	AUX
ct-12609	135	10	often	often	ADV
ct-12609	135	11	associated	associate	VERB
ct-12609	135	12	with	with	ADP
ct-12609	135	13	obesity	obesity	NOUN
ct-12609	135	14	and	and	CCONJ
ct-12609	135	15	characterized	characterize	VERB
ct-12609	135	16	by	by	ADP
ct-12609	135	17	several	several	ADJ
ct-12609	135	18	clinical	clinical	ADJ
ct-12609	135	19	signs	sign	NOUN
ct-12609	135	20	,	,	PUNCT
ct-12609	135	21	neuroendocrine	neuroendocrine	NOUN
ct-12609	135	22	and	and	CCONJ
ct-12609	135	23	metabolic	metabolic	NOUN
ct-12609	135	24	alterations	alteration	NOUN
ct-12609	135	25	.	.	PUNCT
ct-12609	136	1	clinical	clinical	ADJ
ct-12609	136	2	signs	sign	NOUN
ct-12609	136	3	that	that	PRON
ct-12609	136	4	are	be	AUX
ct-12609	136	5	diagnostic	diagnostic	ADJ
ct-12609	136	6	in	in	ADP
ct-12609	136	7	women	woman	NOUN
ct-12609	136	8	are	be	AUX
ct-12609	136	9	:	:	PUNCT
ct-12609	136	10	ovulatory	ovulatory	ADJ
ct-12609	136	11	dysfunction	dysfunction	NOUN
ct-12609	136	12	,	,	PUNCT
ct-12609	136	13	clinical	clinical	ADJ
ct-12609	136	14	hyperandrogenism	hyperandrogenism	NOUN
ct-12609	136	15	(	(	PUNCT
ct-12609	136	16	hirsutism	hirsutism	NOUN
ct-12609	136	17	,	,	PUNCT
ct-12609	136	18	alopecia	alopecia	NOUN
ct-12609	136	19	,	,	PUNCT
ct-12609	136	20	acne	acne	NOUN
ct-12609	136	21	)	)	PUNCT
ct-12609	136	22	and	and	CCONJ
ct-12609	136	23	ir	ir	PROPN
ct-12609	136	24	/	/	SYM
ct-12609	136	25	hyperinsulinemia.13	hyperinsulinemia.13	NOUN
ct-12609	136	26	neuroendocrine	neuroendocrine	NOUN
ct-12609	136	27	disturbances	disturbance	NOUN
ct-12609	136	28	associated	associate	VERB
ct-12609	136	29	with	with	ADP
ct-12609	136	30	pos	pos	NOUN
ct-12609	136	31	include	include	VERB
ct-12609	136	32	an	an	DET
ct-12609	136	33	increase	increase	NOUN
ct-12609	136	34	in	in	ADP
ct-12609	136	35	gnrh	gnrh	NOUN
ct-12609	136	36	pulses	pulse	NOUN
ct-12609	136	37	that	that	PRON
ct-12609	136	38	selectively	selectively	ADV
ct-12609	136	39	stimulate	stimulate	VERB
ct-12609	136	40	lh	lh	NOUN
ct-12609	136	41	release	release	NOUN
ct-12609	136	42	but	but	CCONJ
ct-12609	136	43	not	not	PART
ct-12609	136	44	fsh	fsh	NOUN
ct-12609	136	45	.	.	PUNCT
ct-12609	137	1	lh	lh	PROPN
ct-12609	137	2	stimulates	stimulate	VERB
ct-12609	137	3	the	the	DET
ct-12609	137	4	expression	expression	NOUN
ct-12609	137	5	of	of	ADP
ct-12609	137	6	the	the	DET
ct-12609	137	7	p450c17	p450c17	X
ct-12609	137	8	cytochrome	cytochrome	NOUN
ct-12609	137	9	in	in	ADP
ct-12609	137	10	the	the	DET
ct-12609	137	11	theca	theca	NOUN
ct-12609	137	12	cells	cell	NOUN
ct-12609	137	13	,	,	PUNCT
ct-12609	137	14	increasing	increase	VERB
ct-12609	137	15	the	the	DET
ct-12609	137	16	production	production	NOUN
ct-12609	137	17	of	of	ADP
ct-12609	137	18	17α	17α	ADV
ct-12609	137	19	-	-	PUNCT
ct-12609	137	20	hydroxyprogesterone	hydroxyprogesterone	NOUN
ct-12609	137	21	and	and	CCONJ
ct-12609	137	22	testosterone	testosterone	NOUN
ct-12609	137	23	.	.	PUNCT
ct-12609	138	1	this	this	DET
ct-12609	138	2	hormonal	hormonal	ADJ
ct-12609	138	3	environment	environment	NOUN
ct-12609	138	4	(	(	PUNCT
ct-12609	138	5	↑lh/↓fsh	↑lh/↓fsh	PROPN
ct-12609	138	6	)	)	PUNCT
ct-12609	138	7	impairs	impair	VERB
ct-12609	138	8	follicular	follicular	ADJ
ct-12609	138	9	maturation	maturation	NOUN
ct-12609	138	10	,	,	PUNCT
ct-12609	138	11	decreases	decrease	VERB
ct-12609	138	12	the	the	DET
ct-12609	138	13	number	number	NOUN
ct-12609	138	14	of	of	ADP
ct-12609	138	15	granulosa	granulosa	NOUN
ct-12609	138	16	cells	cell	NOUN
ct-12609	138	17	and	and	CCONJ
ct-12609	138	18	aromatization	aromatization	NOUN
ct-12609	138	19	(	(	PUNCT
ct-12609	138	20	↓e2	↓e2	NOUN
ct-12609	138	21	)	)	PUNCT
ct-12609	138	22	,	,	PUNCT
ct-12609	138	23	and	and	CCONJ
ct-12609	138	24	inhibits	inhibit	VERB
ct-12609	138	25	normal	normal	ADJ
ct-12609	138	26	ovulation.13	ovulation.13	NUM
ct-12609	138	27	insulin	insulin	NOUN
ct-12609	138	28	resistance	resistance	NOUN
ct-12609	138	29	/	/	SYM
ct-12609	138	30	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	138	31	may	may	AUX
ct-12609	138	32	have	have	VERB
ct-12609	138	33	some	some	DET
ct-12609	138	34	role	role	NOUN
ct-12609	138	35	since	since	SCONJ
ct-12609	138	36	administration	administration	NOUN
ct-12609	138	37	of	of	ADP
ct-12609	138	38	metformin	metformin	PROPN
ct-12609	138	39	decreases	decrease	VERB
ct-12609	138	40	the	the	DET
ct-12609	138	41	plasma	plasma	NOUN
ct-12609	138	42	levels	level	NOUN
ct-12609	138	43	of	of	ADP
ct-12609	138	44	insulin	insulin	NOUN
ct-12609	138	45	,	,	PUNCT
ct-12609	138	46	lh	lh	NOUN
ct-12609	138	47	and	and	CCONJ
ct-12609	138	48	androgens	androgen	NOUN
ct-12609	138	49	in	in	ADP
ct-12609	138	50	women.13,22	women.13,22	NOUN
ct-12609	138	51	the	the	DET
ct-12609	138	52	increased	increase	VERB
ct-12609	138	53	level	level	NOUN
ct-12609	138	54	of	of	ADP
ct-12609	138	55	insulin	insulin	NOUN
ct-12609	138	56	and	and	CCONJ
ct-12609	138	57	498	498	NUM
ct-12609	138	58	insulin	insulin	NOUN
ct-12609	138	59	like	like	ADP
ct-12609	138	60	growth	growth	NOUN
ct-12609	138	61	factor-1	factor-1	PROPN
ct-12609	138	62	(	(	PUNCT
ct-12609	138	63	igf-1	igf-1	NOUN
ct-12609	138	64	)	)	PUNCT
ct-12609	138	65	directly	directly	ADV
ct-12609	138	66	target	target	VERB
ct-12609	138	67	the	the	DET
ct-12609	138	68	theca	theca	NOUN
ct-12609	138	69	cells	cell	NOUN
ct-12609	138	70	acting	act	VERB
ct-12609	138	71	in	in	ADP
ct-12609	138	72	synergism	synergism	NOUN
ct-12609	138	73	with	with	ADP
ct-12609	138	74	lh	lh	PROPN
ct-12609	138	75	,	,	PUNCT
ct-12609	138	76	stimulating	stimulate	VERB
ct-12609	138	77	p450c17	p450c17	ADP
ct-12609	138	78	cytochrome	cytochrome	ADJ
ct-12609	138	79	production	production	NOUN
ct-12609	138	80	and	and	CCONJ
ct-12609	138	81	hyperandrogenism	hyperandrogenism	NOUN
ct-12609	138	82	.	.	PUNCT
ct-12609	139	1	they	they	PRON
ct-12609	139	2	also	also	ADV
ct-12609	139	3	decrease	decrease	VERB
ct-12609	139	4	the	the	DET
ct-12609	139	5	hepatic	hepatic	ADJ
ct-12609	139	6	secretion	secretion	NOUN
ct-12609	139	7	of	of	ADP
ct-12609	139	8	the	the	DET
ct-12609	139	9	sexual	sexual	ADJ
ct-12609	139	10	hormone	hormone	NOUN
ct-12609	139	11	binding	bind	VERB
ct-12609	139	12	globulins	globulin	NOUN
ct-12609	139	13	(	(	PUNCT
ct-12609	139	14	shbg	shbg	NOUN
ct-12609	139	15	)	)	PUNCT
ct-12609	139	16	and	and	CCONJ
ct-12609	139	17	the	the	DET
ct-12609	139	18	ifg	ifg	NOUN
ct-12609	139	19	binding	bind	VERB
ct-12609	139	20	proteins	protein	NOUN
ct-12609	139	21	(	(	PUNCT
ct-12609	139	22	igfbp-1	igfbp-1	NOUN
ct-12609	139	23	)	)	PUNCT
ct-12609	139	24	producing	produce	VERB
ct-12609	139	25	hyperandrogenism	hyperandrogenism	NOUN
ct-12609	139	26	by	by	ADP
ct-12609	139	27	increasing	increase	VERB
ct-12609	139	28	the	the	DET
ct-12609	139	29	free	free	ADJ
ct-12609	139	30	testosterone	testosterone	NOUN
ct-12609	139	31	fraction	fraction	NOUN
ct-12609	139	32	and	and	CCONJ
ct-12609	139	33	the	the	DET
ct-12609	139	34	igf1	igf1	PROPN
ct-12609	139	35	bioactivity.13	bioactivity.13	NOUN
ct-12609	139	36	there	there	PRON
ct-12609	139	37	are	be	VERB
ct-12609	139	38	limited	limited	ADJ
ct-12609	139	39	studies	study	NOUN
ct-12609	139	40	in	in	ADP
ct-12609	139	41	the	the	DET
ct-12609	139	42	mare	mare	NOUN
ct-12609	139	43	on	on	ADP
ct-12609	139	44	the	the	DET
ct-12609	139	45	endocrine	endocrine	NOUN
ct-12609	139	46	effects	effect	NOUN
ct-12609	139	47	of	of	ADP
ct-12609	139	48	ir	ir	PROPN
ct-12609	139	49	,	,	PUNCT
ct-12609	139	50	ms	ms	NOUN
ct-12609	139	51	,	,	PUNCT
ct-12609	139	52	or	or	CCONJ
ct-12609	139	53	ppid	ppid	NOUN
ct-12609	139	54	on	on	ADP
ct-12609	139	55	reproductive	reproductive	ADJ
ct-12609	139	56	function	function	NOUN
ct-12609	139	57	.	.	PUNCT
ct-12609	140	1	one	one	NUM
ct-12609	140	2	study	study	NOUN
ct-12609	140	3	showed	show	VERB
ct-12609	140	4	that	that	SCONJ
ct-12609	140	5	a	a	DET
ct-12609	140	6	great	great	ADJ
ct-12609	140	7	proportion	proportion	NOUN
ct-12609	140	8	of	of	ADP
ct-12609	140	9	obese	obese	ADJ
ct-12609	140	10	mares	mare	NOUN
ct-12609	140	11	continued	continue	VERB
ct-12609	140	12	to	to	PART
ct-12609	140	13	cycle	cycle	VERB
ct-12609	140	14	during	during	ADP
ct-12609	140	15	the	the	DET
ct-12609	140	16	winter	winter	NOUN
ct-12609	140	17	compared	compare	VERB
ct-12609	140	18	to	to	PART
ct-12609	140	19	lean	lean	VERB
ct-12609	140	20	mares.23,24	mares.23,24	NOUN
ct-12609	140	21	it	it	PRON
ct-12609	140	22	was	be	AUX
ct-12609	140	23	speculated	speculate	VERB
ct-12609	140	24	that	that	SCONJ
ct-12609	140	25	metabolic	metabolic	NOUN
ct-12609	140	26	alterations	alteration	NOUN
ct-12609	140	27	in	in	ADP
ct-12609	140	28	the	the	DET
ct-12609	140	29	form	form	NOUN
ct-12609	140	30	of	of	ADP
ct-12609	140	31	excessive	excessive	ADJ
ct-12609	140	32	energy	energy	NOUN
ct-12609	140	33	imbalance	imbalance	NOUN
ct-12609	140	34	may	may	AUX
ct-12609	140	35	lead	lead	VERB
ct-12609	140	36	to	to	ADP
ct-12609	140	37	continuous	continuous	ADJ
ct-12609	140	38	cycling	cycling	NOUN
ct-12609	140	39	during	during	ADP
ct-12609	140	40	winter.23,25	winter.23,25	PROPN
ct-12609	140	41	later	later	PROPN
ct-12609	140	42	studies	study	NOUN
ct-12609	140	43	found	find	VERB
ct-12609	140	44	that	that	SCONJ
ct-12609	140	45	obese	obese	ADJ
ct-12609	140	46	mares	mare	NOUN
ct-12609	140	47	had	have	VERB
ct-12609	140	48	aberrations	aberration	NOUN
ct-12609	140	49	in	in	ADP
ct-12609	140	50	the	the	DET
ct-12609	140	51	duration	duration	NOUN
ct-12609	140	52	of	of	ADP
ct-12609	140	53	the	the	DET
ct-12609	140	54	estrous	estrous	ADJ
ct-12609	140	55	cycle	cycle	NOUN
ct-12609	140	56	:	:	PUNCT
ct-12609	140	57	longer	long	ADJ
ct-12609	140	58	inter	inter	ADJ
ct-12609	140	59	-	-	ADJ
ct-12609	140	60	estrus	estrus	ADJ
ct-12609	140	61	intervals	interval	NOUN
ct-12609	140	62	(	(	PUNCT
ct-12609	140	63	36.72	36.72	NUM
ct-12609	140	64	+	+	NOUN
ct-12609	140	65	4.77	4.77	NUM
ct-12609	140	66	vs.	vs.	ADP
ct-12609	140	67	26.00	26.00	NUM
ct-12609	140	68	+	+	NOUN
ct-12609	140	69	0.54	0.54	NUM
ct-12609	140	70	days	day	NOUN
ct-12609	140	71	)	)	PUNCT
ct-12609	140	72	,	,	PUNCT
ct-12609	140	73	prolonged	prolong	VERB
ct-12609	140	74	luteal	luteal	ADJ
ct-12609	140	75	phases	phase	NOUN
ct-12609	140	76	(	(	PUNCT
ct-12609	140	77	30.00	30.00	NUM
ct-12609	140	78	+	+	NUM
ct-12609	140	79	5.55	5.55	NUM
ct-12609	140	80	vs.	vs.	ADP
ct-12609	140	81	17.67	17.67	NUM
ct-12609	140	82	+	+	NUM
ct-12609	140	83	0.18	0.18	NUM
ct-12609	140	84	days	day	NOUN
ct-12609	140	85	)	)	PUNCT
ct-12609	140	86	and	and	CCONJ
ct-12609	140	87	a	a	DET
ct-12609	140	88	higher	high	ADJ
ct-12609	140	89	incidence	incidence	NOUN
ct-12609	140	90	of	of	ADP
ct-12609	140	91	anovulatory	anovulatory	NOUN
ct-12609	140	92	follicles	follicle	NOUN
ct-12609	140	93	compared	compare	VERB
ct-12609	140	94	to	to	PART
ct-12609	140	95	lean	lean	VERB
ct-12609	140	96	mares.23,26	mares.23,26	ADJ
ct-12609	140	97	progesterone	progesterone	NOUN
ct-12609	140	98	remained	remain	VERB
ct-12609	140	99	elevated	elevated	ADJ
ct-12609	140	100	for	for	ADP
ct-12609	140	101	periods	period	NOUN
ct-12609	140	102	of	of	ADP
ct-12609	140	103	37	37	NUM
ct-12609	140	104	to	to	PART
ct-12609	140	105	78	78	NUM
ct-12609	140	106	days	day	NOUN
ct-12609	140	107	in	in	ADP
ct-12609	140	108	83	83	NUM
ct-12609	140	109	%	%	NOUN
ct-12609	140	110	of	of	ADP
ct-12609	140	111	the	the	DET
ct-12609	140	112	obese	obese	ADJ
ct-12609	140	113	mares	mare	NOUN
ct-12609	140	114	while	while	SCONJ
ct-12609	140	115	the	the	DET
ct-12609	140	116	longest	long	ADJ
ct-12609	140	117	time	time	NOUN
ct-12609	140	118	progesterone	progesterone	NOUN
ct-12609	140	119	was	be	AUX
ct-12609	140	120	elevated	elevate	VERB
ct-12609	140	121	in	in	ADP
ct-12609	140	122	lean	lean	ADJ
ct-12609	140	123	mares	mare	NOUN
ct-12609	140	124	was	be	AUX
ct-12609	140	125	22	22	NUM
ct-12609	140	126	days.24	days.24	NOUN
ct-12609	140	127	the	the	DET
ct-12609	140	128	persistence	persistence	NOUN
ct-12609	140	129	of	of	ADP
ct-12609	140	130	elevated	elevated	ADJ
ct-12609	140	131	serum	serum	NOUN
ct-12609	140	132	levels	level	NOUN
ct-12609	140	133	of	of	ADP
ct-12609	140	134	progesterone	progesterone	NOUN
ct-12609	140	135	in	in	ADP
ct-12609	140	136	obese	obese	ADJ
ct-12609	140	137	mares	mare	NOUN
ct-12609	140	138	was	be	AUX
ct-12609	140	139	thought	think	VERB
ct-12609	140	140	to	to	PART
ct-12609	140	141	be	be	AUX
ct-12609	140	142	associated	associate	VERB
ct-12609	140	143	with	with	ADP
ct-12609	140	144	a	a	DET
ct-12609	140	145	persistent	persistent	ADJ
ct-12609	140	146	corpus	corpus	NOUN
ct-12609	140	147	luteum	luteum	NOUN
ct-12609	140	148	or	or	CCONJ
ct-12609	140	149	luteinization	luteinization	NOUN
ct-12609	140	150	of	of	ADP
ct-12609	140	151	an	an	DET
ct-12609	140	152	anovulatory	anovulatory	PROPN
ct-12609	140	153	follicle.27	follicle.27	PROPN
ct-12609	140	154	ultrasonic	ultrasonic	ADJ
ct-12609	140	155	examination	examination	NOUN
ct-12609	140	156	of	of	ADP
ct-12609	140	157	the	the	DET
ct-12609	140	158	reproductive	reproductive	ADJ
ct-12609	140	159	tract	tract	NOUN
ct-12609	140	160	of	of	ADP
ct-12609	140	161	these	these	DET
ct-12609	140	162	mares	mare	NOUN
ct-12609	140	163	showed	show	VERB
ct-12609	140	164	large	large	ADJ
ct-12609	140	165	,	,	PUNCT
ct-12609	140	166	persistent	persistent	ADJ
ct-12609	140	167	anovulatory	anovulatory	NOUN
ct-12609	140	168	follicles	follicle	NOUN
ct-12609	140	169	during	during	ADP
ct-12609	140	170	periods	period	NOUN
ct-12609	140	171	of	of	ADP
ct-12609	140	172	elevated	elevate	VERB
ct-12609	140	173	progesterone	progesterone	NOUN
ct-12609	140	174	suggesting	suggest	VERB
ct-12609	140	175	that	that	SCONJ
ct-12609	140	176	one	one	NUM
ct-12609	140	177	or	or	CCONJ
ct-12609	140	178	more	more	ADJ
ct-12609	140	179	mechanisms	mechanism	NOUN
ct-12609	140	180	involved	involve	VERB
ct-12609	140	181	in	in	ADP
ct-12609	140	182	ovulation	ovulation	NOUN
ct-12609	140	183	may	may	AUX
ct-12609	140	184	be	be	AUX
ct-12609	140	185	suppressed	suppress	VERB
ct-12609	140	186	or	or	CCONJ
ct-12609	140	187	inhibited.28	inhibited.28	VERB
ct-12609	140	188	obese	obese	ADJ
ct-12609	140	189	mares	mare	NOUN
ct-12609	140	190	exhibited	exhibit	VERB
ct-12609	140	191	lower	low	ADJ
ct-12609	140	192	levels	level	NOUN
ct-12609	140	193	of	of	ADP
ct-12609	140	194	serum	serum	NOUN
ct-12609	140	195	concentrations	concentration	NOUN
ct-12609	140	196	of	of	ADP
ct-12609	140	197	thyroxine	thyroxine	NOUN
ct-12609	140	198	and	and	CCONJ
ct-12609	140	199	leptin	leptin	NOUN
ct-12609	140	200	and	and	CCONJ
ct-12609	140	201	higher	high	ADJ
ct-12609	140	202	levels	level	NOUN
ct-12609	140	203	of	of	ADP
ct-12609	140	204	insulin	insulin	NOUN
ct-12609	140	205	and	and	CCONJ
ct-12609	140	206	insulin	insulin	NOUN
ct-12609	140	207	insensitivity	insensitivity	NOUN
ct-12609	140	208	compared	compare	VERB
ct-12609	140	209	to	to	ADP
ct-12609	140	210	lean	lean	ADJ
ct-12609	140	211	mares	mare	NOUN
ct-12609	140	212	.	.	PUNCT
ct-12609	141	1	the	the	DET
ct-12609	141	2	mechanism	mechanism	NOUN
ct-12609	141	3	of	of	ADP
ct-12609	141	4	how	how	SCONJ
ct-12609	141	5	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	141	6	and	and	CCONJ
ct-12609	141	7	ir	ir	PROPN
ct-12609	141	8	may	may	AUX
ct-12609	141	9	disrupt	disrupt	VERB
ct-12609	141	10	normal	normal	ADJ
ct-12609	141	11	reproductive	reproductive	ADJ
ct-12609	141	12	activity	activity	NOUN
ct-12609	141	13	is	be	AUX
ct-12609	141	14	unknown	unknown	ADJ
ct-12609	141	15	but	but	CCONJ
ct-12609	141	16	the	the	DET
ct-12609	141	17	following	follow	VERB
ct-12609	141	18	data	datum	NOUN
ct-12609	141	19	suggest	suggest	VERB
ct-12609	141	20	a	a	DET
ct-12609	141	21	direct	direct	ADJ
ct-12609	141	22	effect	effect	NOUN
ct-12609	141	23	on	on	ADP
ct-12609	141	24	the	the	DET
ct-12609	141	25	ovary	ovary	NOUN
ct-12609	141	26	rather	rather	ADV
ct-12609	141	27	than	than	ADP
ct-12609	141	28	the	the	DET
ct-12609	141	29	499	499	NUM
ct-12609	141	30	hypothalamic	hypothalamic	ADJ
ct-12609	141	31	-	-	PUNCT
ct-12609	141	32	pituitary	pituitary	ADJ
ct-12609	141	33	-	-	PUNCT
ct-12609	141	34	ovary	ovary	ADJ
ct-12609	141	35	axis	axis	NOUN
ct-12609	141	36	.	.	PUNCT
ct-12609	142	1	in	in	ADP
ct-12609	142	2	domestic	domestic	ADJ
ct-12609	142	3	species	specie	NOUN
ct-12609	142	4	,	,	PUNCT
ct-12609	142	5	insulin	insulin	NOUN
ct-12609	142	6	in	in	ADP
ct-12609	142	7	combination	combination	NOUN
ct-12609	142	8	with	with	ADP
ct-12609	142	9	igf	igf	PROPN
ct-12609	142	10	,	,	PUNCT
ct-12609	142	11	promotes	promote	VERB
ct-12609	142	12	follicular	follicular	ADJ
ct-12609	142	13	development	development	NOUN
ct-12609	142	14	and	and	CCONJ
ct-12609	142	15	modulates	modulate	NOUN
ct-12609	142	16	ovarian	ovarian	ADJ
ct-12609	142	17	steroids	steroid	NOUN
ct-12609	142	18	secretion	secretion	NOUN
ct-12609	142	19	as	as	SCONJ
ct-12609	142	20	seen	see	VERB
ct-12609	142	21	in	in	ADP
ct-12609	142	22	women	woman	NOUN
ct-12609	142	23	with	with	ADP
ct-12609	142	24	pos.13	pos.13	ADJ
ct-12609	142	25	sessions	session	NOUN
ct-12609	142	26	et	et	PROPN
ct-12609	142	27	al	al	PROPN
ct-12609	142	28	.	.	PROPN
ct-12609	142	29	,	,	PUNCT
ct-12609	142	30	showed	show	VERB
ct-12609	142	31	that	that	SCONJ
ct-12609	142	32	induction	induction	NOUN
ct-12609	142	33	of	of	ADP
ct-12609	142	34	transient	transient	ADJ
ct-12609	142	35	insulin	insulin	NOUN
ct-12609	142	36	resistance	resistance	NOUN
ct-12609	142	37	in	in	ADP
ct-12609	142	38	the	the	DET
ct-12609	142	39	mare	mare	NOUN
ct-12609	142	40	lengthens	lengthen	VERB
ct-12609	142	41	the	the	DET
ct-12609	142	42	interovulatory	interovulatory	ADJ
ct-12609	142	43	interval	interval	NOUN
ct-12609	142	44	(	(	PUNCT
ct-12609	142	45	mean	mean	VERB
ct-12609	142	46	duration	duration	NOUN
ct-12609	142	47	19.57	19.57	NUM
ct-12609	143	1	+	+	NUM
ct-12609	143	2	2.66	2.66	NUM
ct-12609	143	3	vs.	vs.	ADP
ct-12609	143	4	15.57	15.57	NUM
ct-12609	143	5	+	+	SYM
ct-12609	143	6	0.97	0.97	NUM
ct-12609	143	7	d	d	NOUN
ct-12609	143	8	)	)	PUNCT
ct-12609	143	9	,	,	PUNCT
ct-12609	143	10	creates	create	VERB
ct-12609	143	11	higher	high	ADJ
ct-12609	143	12	serum	serum	NOUN
ct-12609	143	13	peak	peak	NOUN
ct-12609	143	14	concentrations	concentration	NOUN
ct-12609	143	15	of	of	ADP
ct-12609	143	16	progesterone	progesterone	NOUN
ct-12609	143	17	(	(	PUNCT
ct-12609	143	18	12.87	12.87	NUM
ct-12609	143	19	+	+	NUM
ct-12609	143	20	4.04	4.04	NUM
ct-12609	143	21	vs.	vs.	ADP
ct-12609	143	22	8.78	8.78	NUM
ct-12609	143	23	+	+	PROPN
ct-12609	143	24	2.23	2.23	NUM
ct-12609	143	25	ng	ng	NOUN
ct-12609	143	26	/	/	SYM
ct-12609	143	27	ml	ml	PROPN
ct-12609	143	28	)	)	PUNCT
ct-12609	143	29	but	but	CCONJ
ct-12609	143	30	does	do	AUX
ct-12609	143	31	not	not	PART
ct-12609	143	32	affect	affect	VERB
ct-12609	143	33	serum	serum	NOUN
ct-12609	143	34	lh	lh	PROPN
ct-12609	143	35	concentrations	concentration	NOUN
ct-12609	143	36	(	(	PUNCT
ct-12609	143	37	3.9	3.9	NUM
ct-12609	143	38	+	+	SYM
ct-12609	143	39	0.34	0.34	NUM
ct-12609	143	40	vs.	vs.	ADP
ct-12609	143	41	3.29	3.29	NUM
ct-12609	143	42	+	+	PROPN
ct-12609	143	43	0.13	0.13	NUM
ct-12609	143	44	ng	ng	PROPN
ct-12609	143	45	/	/	SYM
ct-12609	143	46	ml	ml	NOUN
ct-12609	143	47	)	)	PUNCT
ct-12609	143	48	when	when	SCONJ
ct-12609	143	49	compared	compare	VERB
ct-12609	143	50	to	to	PART
ct-12609	143	51	control	control	VERB
ct-12609	143	52	mares.29	mares.29	NOUN
ct-12609	143	53	]	]	PUNCT
ct-12609	143	54	in	in	ADP
ct-12609	143	55	women	woman	NOUN
ct-12609	143	56	,	,	PUNCT
ct-12609	143	57	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	143	58	affects	affect	VERB
ct-12609	143	59	the	the	DET
ct-12609	143	60	menstrual	menstrual	ADJ
ct-12609	143	61	cycle	cycle	NOUN
ct-12609	143	62	by	by	ADP
ct-12609	143	63	alterations	alteration	NOUN
ct-12609	143	64	of	of	ADP
ct-12609	143	65	the	the	DET
ct-12609	143	66	gnrh	gnrh	NOUN
ct-12609	143	67	-	-	PUNCT
ct-12609	143	68	mediated	mediate	VERB
ct-12609	143	69	lh	lh	PROPN
ct-12609	143	70	release	release	NOUN
ct-12609	143	71	and	and	CCONJ
ct-12609	143	72	has	have	VERB
ct-12609	143	73	a	a	DET
ct-12609	143	74	direct	direct	ADJ
ct-12609	143	75	effect	effect	NOUN
ct-12609	143	76	on	on	ADP
ct-12609	143	77	the	the	DET
ct-12609	143	78	ovary	ovary	NOUN
ct-12609	143	79	by	by	ADP
ct-12609	143	80	increasing	increase	VERB
ct-12609	143	81	steroid	steroid	NOUN
ct-12609	143	82	secretions.30,31	secretions.30,31	NOUN
ct-12609	143	83	this	this	DET
ct-12609	143	84	phenomenon	phenomenon	NOUN
ct-12609	143	85	is	be	AUX
ct-12609	143	86	well	well	ADV
ct-12609	143	87	documented	document	VERB
ct-12609	143	88	in	in	ADP
ct-12609	143	89	women	woman	NOUN
ct-12609	143	90	with	with	ADP
ct-12609	143	91	pos	pos	NOUN
ct-12609	143	92	where	where	SCONJ
ct-12609	143	93	there	there	PRON
ct-12609	143	94	is	be	VERB
ct-12609	143	95	an	an	DET
ct-12609	143	96	arrest	arrest	NOUN
ct-12609	143	97	of	of	ADP
ct-12609	143	98	follicular	follicular	ADJ
ct-12609	143	99	development	development	NOUN
ct-12609	143	100	.	.	PUNCT
ct-12609	144	1	apparently	apparently	ADV
ct-12609	144	2	,	,	PUNCT
ct-12609	144	3	small	small	ADJ
ct-12609	144	4	follicles	follicle	NOUN
ct-12609	144	5	that	that	PRON
ct-12609	144	6	just	just	ADV
ct-12609	144	7	attained	attain	VERB
ct-12609	144	8	lh	lh	PROPN
ct-12609	144	9	receptors	receptor	NOUN
ct-12609	144	10	,	,	PUNCT
ct-12609	144	11	in	in	ADP
ct-12609	144	12	the	the	DET
ct-12609	144	13	presence	presence	NOUN
ct-12609	144	14	of	of	ADP
ct-12609	144	15	insulin	insulin	NOUN
ct-12609	144	16	and	and	CCONJ
ct-12609	144	17	high	high	ADJ
ct-12609	144	18	lh	lh	PROPN
ct-12609	144	19	,	,	PUNCT
ct-12609	144	20	produce	produce	VERB
ct-12609	144	21	estradiol	estradiol	PROPN
ct-12609	144	22	levels	level	NOUN
ct-12609	144	23	that	that	PRON
ct-12609	144	24	are	be	AUX
ct-12609	144	25	similar	similar	ADJ
ct-12609	144	26	to	to	ADP
ct-12609	144	27	levels	level	NOUN
ct-12609	144	28	produced	produce	VERB
ct-12609	144	29	by	by	ADP
ct-12609	144	30	mature	mature	ADJ
ct-12609	144	31	follicles	follicle	NOUN
ct-12609	144	32	,	,	PUNCT
ct-12609	144	33	thereby	thereby	ADV
ct-12609	144	34	inhibiting	inhibit	VERB
ct-12609	144	35	growth	growth	NOUN
ct-12609	144	36	and	and	CCONJ
ct-12609	144	37	arresting	arrest	VERB
ct-12609	144	38	follicles	follicle	NOUN
ct-12609	144	39	in	in	ADP
ct-12609	144	40	the	the	DET
ct-12609	144	41	immature	immature	ADJ
ct-12609	144	42	stage	stage	NOUN
ct-12609	144	43	.	.	PUNCT
ct-12609	145	1	a	a	DET
ct-12609	145	2	similar	similar	ADJ
ct-12609	145	3	phenomenon	phenomenon	NOUN
ct-12609	145	4	may	may	AUX
ct-12609	145	5	be	be	AUX
ct-12609	145	6	occurring	occur	VERB
ct-12609	145	7	in	in	ADP
ct-12609	145	8	the	the	DET
ct-12609	145	9	mare	mare	NOUN
ct-12609	145	10	with	with	ADP
ct-12609	145	11	insulin	insulin	NOUN
ct-12609	145	12	resistance	resistance	NOUN
ct-12609	145	13	;	;	PUNCT
ct-12609	145	14	however	however	ADV
ct-12609	145	15	it	it	PRON
ct-12609	145	16	appears	appear	VERB
ct-12609	145	17	to	to	PART
ct-12609	145	18	be	be	AUX
ct-12609	145	19	due	due	ADJ
ct-12609	145	20	to	to	ADP
ct-12609	145	21	a	a	DET
ct-12609	145	22	direct	direct	ADJ
ct-12609	145	23	effect	effect	NOUN
ct-12609	145	24	of	of	ADP
ct-12609	145	25	insulin	insulin	NOUN
ct-12609	145	26	on	on	ADP
ct-12609	145	27	the	the	DET
ct-12609	145	28	ovary	ovary	NOUN
ct-12609	145	29	since	since	SCONJ
ct-12609	145	30	the	the	DET
ct-12609	145	31	hypothalamic	hypothalamic	ADJ
ct-12609	145	32	-	-	PUNCT
ct-12609	145	33	pituitary	pituitary	ADJ
ct-12609	145	34	axis	axis	NOUN
ct-12609	145	35	was	be	AUX
ct-12609	145	36	not	not	PART
ct-12609	145	37	affected	affect	VERB
ct-12609	145	38	during	during	ADP
ct-12609	145	39	an	an	DET
ct-12609	145	40	induced	induced	ADJ
ct-12609	145	41	short	short	ADJ
ct-12609	145	42	term	term	NOUN
ct-12609	145	43	hyperinsulinemia	hyperinsulinemia	NOUN
ct-12609	145	44	.	.	PUNCT
ct-12609	146	1	peak	peak	NOUN
ct-12609	146	2	concentrations	concentration	NOUN
ct-12609	146	3	of	of	ADP
ct-12609	146	4	progesterone	progesterone	NOUN
ct-12609	146	5	were	be	AUX
ct-12609	146	6	higher	high	ADJ
ct-12609	146	7	in	in	ADP
ct-12609	146	8	mares	mare	NOUN
ct-12609	146	9	experiencing	experience	VERB
ct-12609	146	10	transient	transient	ADJ
ct-12609	146	11	ir	ir	PROPN
ct-12609	146	12	compared	compare	VERB
ct-12609	146	13	to	to	PART
ct-12609	146	14	control	control	VERB
ct-12609	146	15	mares	mare	NOUN
ct-12609	146	16	suggesting	suggest	VERB
ct-12609	146	17	an	an	DET
ct-12609	146	18	increased	increase	VERB
ct-12609	146	19	steroid	steroid	NOUN
ct-12609	146	20	secretion	secretion	NOUN
ct-12609	146	21	by	by	ADP
ct-12609	146	22	the	the	DET
ct-12609	146	23	ovary	ovary	NOUN
ct-12609	146	24	.	.	PUNCT
ct-12609	147	1	it	it	PRON
ct-12609	147	2	has	have	AUX
ct-12609	147	3	been	be	AUX
ct-12609	147	4	proposed	propose	VERB
ct-12609	147	5	that	that	SCONJ
ct-12609	147	6	insulin	insulin	NOUN
ct-12609	147	7	has	have	VERB
ct-12609	147	8	a	a	DET
ct-12609	147	9	stimulatory	stimulatory	ADJ
ct-12609	147	10	effect	effect	NOUN
ct-12609	147	11	on	on	ADP
ct-12609	147	12	progesterone	progesterone	NOUN
ct-12609	147	13	production	production	NOUN
ct-12609	147	14	by	by	ADP
ct-12609	147	15	luteal	luteal	ADJ
ct-12609	147	16	tissue	tissue	NOUN
ct-12609	147	17	and	and	CCONJ
ct-12609	147	18	this	this	DET
ct-12609	147	19	effect	effect	NOUN
ct-12609	147	20	is	be	AUX
ct-12609	147	21	mediated	mediate	VERB
ct-12609	147	22	by	by	ADP
ct-12609	147	23	changes	change	NOUN
ct-12609	147	24	in	in	ADP
ct-12609	147	25	the	the	DET
ct-12609	147	26	developing	develop	VERB
ct-12609	147	27	follicle	follicle	NOUN
ct-12609	147	28	.	.	PUNCT
ct-12609	148	1	in	in	ADP
ct-12609	148	2	studying	study	VERB
ct-12609	148	3	the	the	DET
ct-12609	148	4	repeatability	repeatability	NOUN
ct-12609	148	5	of	of	ADP
ct-12609	148	6	hemorrhagic	hemorrhagic	NOUN
ct-12609	148	7	anovulatory	anovulatory	NOUN
ct-12609	148	8	follicles	follicle	NOUN
ct-12609	148	9	(	(	PUNCT
ct-12609	148	10	haf	haf	NOUN
ct-12609	148	11	)	)	PUNCT
ct-12609	148	12	in	in	ADP
ct-12609	148	13	ponies	pony	NOUN
ct-12609	148	14	,	,	PUNCT
ct-12609	148	15	ginther	ginther	NOUN
ct-12609	148	16	also	also	ADV
ct-12609	148	17	deflected	deflect	VERB
ct-12609	148	18	the	the	DET
ct-12609	148	19	focus	focus	NOUN
ct-12609	148	20	from	from	ADP
ct-12609	148	21	the	the	DET
ct-12609	148	22	hypothalamic	hypothalamic	ADJ
ct-12609	148	23	-	-	PUNCT
ct-12609	148	24	pituitary	pituitary	ADJ
ct-12609	148	25	-	-	PUNCT
ct-12609	148	26	ovary	ovary	NOUN
ct-12609	148	27	axis.32	axis.32	NOUN
ct-12609	148	28	he	he	PRON
ct-12609	148	29	showed	show	VERB
ct-12609	148	30	that	that	SCONJ
ct-12609	148	31	follicular	follicular	ADJ
ct-12609	148	32	diameter	diameter	NOUN
ct-12609	148	33	,	,	PUNCT
ct-12609	148	34	levels	level	NOUN
ct-12609	148	35	of	of	ADP
ct-12609	148	36	lh	lh	PROPN
ct-12609	148	37	and	and	CCONJ
ct-12609	148	38	progesterone	progesterone	NOUN
ct-12609	148	39	were	be	AUX
ct-12609	148	40	similar	similar	ADJ
ct-12609	148	41	in	in	ADP
ct-12609	148	42	ovulating	ovulating	NOUN
ct-12609	148	43	and	and	CCONJ
ct-12609	148	44	haf	haf	PROPN
ct-12609	148	45	mares	mare	NOUN
ct-12609	148	46	before	before	ADV
ct-12609	148	47	and	and	CCONJ
ct-12609	148	48	at	at	ADP
ct-12609	148	49	the	the	DET
ct-12609	148	50	day	day	NOUN
ct-12609	148	51	of	of	ADP
ct-12609	148	52	ovulation	ovulation	NOUN
ct-12609	148	53	.	.	PUNCT
ct-12609	149	1	the	the	DET
ct-12609	149	2	impact	impact	NOUN
ct-12609	149	3	of	of	ADP
ct-12609	149	4	his	his	PRON
ct-12609	149	5	findings	finding	NOUN
ct-12609	149	6	on	on	ADP
ct-12609	149	7	obese	obese	ADJ
ct-12609	149	8	mares	mare	NOUN
ct-12609	149	9	remains	remain	VERB
ct-12609	149	10	unknown	unknown	ADJ
ct-12609	149	11	.	.	PUNCT
ct-12609	150	1	500	500	NUM
ct-12609	150	2	the	the	DET
ct-12609	150	3	longer	long	ADV
ct-12609	150	4	interovulatory	interovulatory	ADJ
ct-12609	150	5	interval	interval	NOUN
ct-12609	150	6	in	in	ADP
ct-12609	150	7	obese	obese	ADJ
ct-12609	150	8	mares	mare	NOUN
ct-12609	150	9	appears	appear	VERB
ct-12609	150	10	to	to	PART
ct-12609	150	11	be	be	AUX
ct-12609	150	12	due	due	ADJ
ct-12609	150	13	to	to	ADP
ct-12609	150	14	luteinization	luteinization	NOUN
ct-12609	150	15	without	without	ADP
ct-12609	150	16	ovulation	ovulation	NOUN
ct-12609	150	17	of	of	ADP
ct-12609	150	18	the	the	DET
ct-12609	150	19	dominant	dominant	ADJ
ct-12609	150	20	follicle	follicle	NOUN
ct-12609	150	21	(	(	PUNCT
ct-12609	150	22	failure	failure	NOUN
ct-12609	150	23	to	to	PART
ct-12609	150	24	ovulate	ovulate	VERB
ct-12609	150	25	)	)	PUNCT
ct-12609	150	26	extending	extend	VERB
ct-12609	150	27	the	the	DET
ct-12609	150	28	luteal	luteal	ADJ
ct-12609	150	29	phase	phase	NOUN
ct-12609	150	30	.	.	PUNCT
ct-12609	151	1	one	one	NUM
ct-12609	151	2	plausible	plausible	ADJ
ct-12609	151	3	explanation	explanation	NOUN
ct-12609	151	4	is	be	AUX
ct-12609	151	5	what	what	PRON
ct-12609	151	6	happens	happen	VERB
ct-12609	151	7	in	in	ADP
ct-12609	151	8	women	woman	NOUN
ct-12609	151	9	with	with	ADP
ct-12609	151	10	pos	pos	NOUN
ct-12609	151	11	;	;	PUNCT
ct-12609	151	12	insulin	insulin	NOUN
ct-12609	151	13	directly	directly	ADV
ct-12609	151	14	targets	target	VERB
ct-12609	151	15	the	the	DET
ct-12609	151	16	theca	theca	NOUN
ct-12609	151	17	cell	cell	NOUN
ct-12609	151	18	stimulating	stimulate	VERB
ct-12609	151	19	p450c17	p450c17	ADP
ct-12609	151	20	cytochrome	cytochrome	ADJ
ct-12609	151	21	production	production	NOUN
ct-12609	151	22	and	and	CCONJ
ct-12609	151	23	hyperandrogenism	hyperandrogenism	NOUN
ct-12609	151	24	.	.	PUNCT
ct-12609	152	1	increased	increase	VERB
ct-12609	152	2	androgen	androgen	NOUN
ct-12609	152	3	inhibits	inhibit	VERB
ct-12609	152	4	fsh	fsh	ADJ
ct-12609	152	5	secretion	secretion	NOUN
ct-12609	152	6	and	and	CCONJ
ct-12609	152	7	this	this	DET
ct-12609	152	8	hormonal	hormonal	ADJ
ct-12609	152	9	environment	environment	NOUN
ct-12609	152	10	(	(	PUNCT
ct-12609	152	11	↑androgens/↓fsh	↑androgens/↓fsh	NOUN
ct-12609	152	12	)	)	PUNCT
ct-12609	152	13	impairs	impair	VERB
ct-12609	152	14	follicular	follicular	ADJ
ct-12609	152	15	maturation	maturation	NOUN
ct-12609	152	16	,	,	PUNCT
ct-12609	152	17	decreases	decrease	VERB
ct-12609	152	18	the	the	DET
ct-12609	152	19	number	number	NOUN
ct-12609	152	20	of	of	ADP
ct-12609	152	21	granulosa	granulosa	NOUN
ct-12609	152	22	cells	cell	NOUN
ct-12609	152	23	and	and	CCONJ
ct-12609	152	24	aromatization	aromatization	NOUN
ct-12609	152	25	(	(	PUNCT
ct-12609	152	26	↓e2	↓e2	NOUN
ct-12609	152	27	)	)	PUNCT
ct-12609	152	28	,	,	PUNCT
ct-12609	152	29	and	and	CCONJ
ct-12609	152	30	inhibits	inhibit	VERB
ct-12609	152	31	normal	normal	ADJ
ct-12609	152	32	ovulation	ovulation	NOUN
ct-12609	152	33	.	.	PUNCT
ct-12609	153	1	further	further	ADJ
ct-12609	153	2	studies	study	NOUN
ct-12609	153	3	need	need	VERB
ct-12609	153	4	to	to	PART
ct-12609	153	5	be	be	AUX
ct-12609	153	6	performed	perform	VERB
ct-12609	153	7	to	to	PART
ct-12609	153	8	confirm	confirm	VERB
ct-12609	153	9	this	this	DET
ct-12609	153	10	theory	theory	NOUN
ct-12609	153	11	by	by	ADP
ct-12609	153	12	measuring	measure	VERB
ct-12609	153	13	androgens	androgen	NOUN
ct-12609	153	14	and	and	CCONJ
ct-12609	153	15	fsh	fsh	NOUN
ct-12609	153	16	in	in	ADP
ct-12609	153	17	mares	mare	NOUN
ct-12609	153	18	with	with	ADP
ct-12609	153	19	persistent	persistent	ADJ
ct-12609	153	20	ir	ir	PROPN
ct-12609	153	21	.	.	PUNCT
ct-12609	154	1	another	another	DET
ct-12609	154	2	explanation	explanation	NOUN
ct-12609	154	3	,	,	PUNCT
ct-12609	154	4	which	which	PRON
ct-12609	154	5	does	do	AUX
ct-12609	154	6	not	not	PART
ct-12609	154	7	exclude	exclude	VERB
ct-12609	154	8	the	the	DET
ct-12609	154	9	prior	prior	ADJ
ct-12609	154	10	,	,	PUNCT
ct-12609	154	11	is	be	AUX
ct-12609	154	12	that	that	SCONJ
ct-12609	154	13	elevated	elevated	ADJ
ct-12609	154	14	insulin	insulin	NOUN
ct-12609	154	15	affects	affect	VERB
ct-12609	154	16	follicle	follicle	NOUN
ct-12609	154	17	remodeling	remodeling	NOUN
ct-12609	154	18	mechanisms	mechanism	NOUN
ct-12609	154	19	necessary	necessary	ADJ
ct-12609	154	20	for	for	ADP
ct-12609	154	21	ovulation	ovulation	NOUN
ct-12609	154	22	.	.	PUNCT
ct-12609	155	1	normal	normal	ADJ
ct-12609	155	2	follicular	follicular	ADJ
ct-12609	155	3	growth	growth	NOUN
ct-12609	155	4	,	,	PUNCT
ct-12609	155	5	ovulation	ovulation	NOUN
ct-12609	155	6	and	and	CCONJ
ct-12609	155	7	atresia	atresia	NOUN
ct-12609	155	8	require	require	VERB
ct-12609	155	9	remodeling	remodeling	NOUN
ct-12609	155	10	events	event	NOUN
ct-12609	155	11	which	which	PRON
ct-12609	155	12	are	be	AUX
ct-12609	155	13	carried	carry	VERB
ct-12609	155	14	out	out	ADP
ct-12609	155	15	by	by	ADP
ct-12609	155	16	matrix	matrix	NOUN
ct-12609	155	17	metalloproteinases	metalloproteinase	NOUN
ct-12609	155	18	(	(	PUNCT
ct-12609	155	19	mmp	mmp	PROPN
ct-12609	155	20	)	)	PUNCT
ct-12609	155	21	and	and	CCONJ
ct-12609	155	22	tissue	tissue	NOUN
ct-12609	155	23	inhibition	inhibition	NOUN
ct-12609	155	24	of	of	ADP
ct-12609	155	25	metalloproteinases	metalloproteinase	NOUN
ct-12609	155	26	(	(	PUNCT
ct-12609	155	27	timp	timp	NOUN
ct-12609	155	28	)	)	PUNCT
ct-12609	155	29	.	.	PUNCT
ct-12609	156	1	recent	recent	ADJ
ct-12609	156	2	studies	study	NOUN
ct-12609	156	3	indicate	indicate	VERB
ct-12609	156	4	that	that	DET
ct-12609	156	5	exposure	exposure	NOUN
ct-12609	156	6	to	to	ADP
ct-12609	156	7	elevated	elevated	ADJ
ct-12609	156	8	insulin	insulin	NOUN
ct-12609	156	9	affects	affect	VERB
ct-12609	156	10	the	the	DET
ct-12609	156	11	in	in	ADV
ct-12609	156	12	vitro	vitro	X
ct-12609	156	13	expression	expression	NOUN
ct-12609	156	14	of	of	ADP
ct-12609	156	15	mmp	mmp	PROPN
ct-12609	156	16	and	and	CCONJ
ct-12609	156	17	timp	timp	PROPN
ct-12609	156	18	in	in	ADP
ct-12609	156	19	preovulatory	preovulatory	NOUN
ct-12609	156	20	and	and	CCONJ
ct-12609	156	21	atretic	atretic	ADJ
ct-12609	156	22	follicles	follicle	NOUN
ct-12609	156	23	.	.	PUNCT
ct-12609	157	1	moreover	moreover	ADV
ct-12609	157	2	,	,	PUNCT
ct-12609	157	3	it	it	PRON
ct-12609	157	4	specifically	specifically	ADV
ct-12609	157	5	disrupts	disrupt	VERB
ct-12609	157	6	the	the	DET
ct-12609	157	7	expression	expression	NOUN
ct-12609	157	8	of	of	ADP
ct-12609	157	9	timp-2	timp-2	NUM
ct-12609	157	10	modifying	modify	VERB
ct-12609	157	11	the	the	DET
ct-12609	157	12	ratio	ratio	NOUN
ct-12609	157	13	of	of	ADP
ct-12609	157	14	mmp	mmp	PROPN
ct-12609	157	15	/	/	SYM
ct-12609	157	16	timp	timp	NOUN
ct-12609	157	17	expression	expression	NOUN
ct-12609	157	18	by	by	ADP
ct-12609	157	19	equine	equine	NOUN
ct-12609	157	20	granulosa	granulosa	NOUN
ct-12609	157	21	cells	cell	NOUN
ct-12609	157	22	of	of	ADP
ct-12609	157	23	large	large	ADJ
ct-12609	157	24	follicles	follicle	NOUN
ct-12609	157	25	.	.	PUNCT
ct-12609	158	1	this	this	DET
ct-12609	158	2	alteration	alteration	NOUN
ct-12609	158	3	may	may	AUX
ct-12609	158	4	be	be	AUX
ct-12609	158	5	responsible	responsible	ADJ
ct-12609	158	6	for	for	ADP
ct-12609	158	7	the	the	DET
ct-12609	158	8	inability	inability	NOUN
ct-12609	158	9	of	of	ADP
ct-12609	158	10	the	the	DET
ct-12609	158	11	follicular	follicular	ADJ
ct-12609	158	12	wall	wall	NOUN
ct-12609	158	13	to	to	PART
ct-12609	158	14	remodel	remodel	VERB
ct-12609	158	15	for	for	ADP
ct-12609	158	16	development	development	NOUN
ct-12609	158	17	,	,	PUNCT
ct-12609	158	18	migration	migration	NOUN
ct-12609	158	19	and	and	CCONJ
ct-12609	158	20	ovulation.26,33	ovulation.26,33	NOUN
ct-12609	158	21	conclusion	conclusion	NOUN
ct-12609	158	22	although	although	SCONJ
ct-12609	158	23	the	the	DET
ct-12609	158	24	pathophysiology	pathophysiology	NOUN
ct-12609	158	25	of	of	ADP
ct-12609	158	26	metabolic	metabolic	NOUN
ct-12609	158	27	diseases	disease	NOUN
ct-12609	158	28	such	such	ADJ
ct-12609	158	29	as	as	ADP
ct-12609	158	30	ir	ir	PROPN
ct-12609	158	31	,	,	PUNCT
ct-12609	158	32	ms	ms	PROPN
ct-12609	158	33	or	or	CCONJ
ct-12609	158	34	cd	cd	PROPN
ct-12609	158	35	is	be	AUX
ct-12609	158	36	not	not	PART
ct-12609	158	37	completely	completely	ADV
ct-12609	158	38	known	know	VERB
ct-12609	158	39	,	,	PUNCT
ct-12609	158	40	there	there	PRON
ct-12609	158	41	is	be	VERB
ct-12609	158	42	increasing	increase	VERB
ct-12609	158	43	evidence	evidence	NOUN
ct-12609	158	44	that	that	SCONJ
ct-12609	158	45	these	these	DET
ct-12609	158	46	conditions	condition	NOUN
ct-12609	158	47	may	may	AUX
ct-12609	158	48	adversely	adversely	ADV
ct-12609	158	49	impact	impact	VERB
ct-12609	158	50	fertility	fertility	NOUN
ct-12609	158	51	of	of	ADP
ct-12609	158	52	the	the	DET
ct-12609	158	53	mare	mare	NOUN
ct-12609	158	54	.	.	PUNCT
ct-12609	159	1	diagnostic	diagnostic	ADJ
ct-12609	159	2	testing	testing	NOUN
ct-12609	159	3	for	for	ADP
ct-12609	159	4	these	these	DET
ct-12609	159	5	conditions	condition	NOUN
ct-12609	159	6	should	should	AUX
ct-12609	159	7	be	be	AUX
ct-12609	159	8	considered	consider	VERB
ct-12609	159	9	in	in	ADP
ct-12609	159	10	old	old	ADJ
ct-12609	159	11	,	,	PUNCT
ct-12609	159	12	obese	obese	ADJ
ct-12609	159	13	mares	mare	NOUN
ct-12609	159	14	that	that	PRON
ct-12609	159	15	repeatedly	repeatedly	ADV
ct-12609	159	16	form	form	VERB
ct-12609	159	17	anovulatory	anovulatory	NOUN
ct-12609	159	18	follicles	follicle	NOUN
ct-12609	159	19	,	,	PUNCT
ct-12609	159	20	experience	experience	NOUN
ct-12609	159	21	bouts	bout	NOUN
ct-12609	159	22	of	of	ADP
ct-12609	159	23	laminitis	laminitis	NOUN
ct-12609	159	24	or	or	CCONJ
ct-12609	159	25	endometritis	endometritis	NOUN
ct-12609	159	26	.	.	PUNCT
ct-12609	160	1	while	while	SCONJ
ct-12609	160	2	accuracy	accuracy	NOUN
ct-12609	160	3	of	of	ADP
ct-12609	160	4	diagnostic	diagnostic	ADJ
ct-12609	160	5	tests	test	NOUN
ct-12609	160	6	for	for	ADP
ct-12609	160	7	detecting	detect	VERB
ct-12609	160	8	disease	disease	NOUN
ct-12609	160	9	may	may	AUX
ct-12609	160	10	not	not	PART
ct-12609	160	11	be	be	AUX
ct-12609	160	12	as	as	ADV
ct-12609	160	13	high	high	ADJ
ct-12609	160	14	as	as	SCONJ
ct-12609	160	15	one	one	PRON
ct-12609	160	16	would	would	AUX
ct-12609	160	17	like	like	VERB
ct-12609	160	18	,	,	PUNCT
ct-12609	160	19	a	a	DET
ct-12609	160	20	combination	combination	NOUN
ct-12609	160	21	of	of	ADP
ct-12609	160	22	tests	test	NOUN
ct-12609	160	23	along	along	ADP
ct-12609	160	24	with	with	ADP
ct-12609	160	25	clinical	clinical	ADJ
ct-12609	160	26	assessment	assessment	NOUN
ct-12609	160	27	will	will	AUX
ct-12609	160	28	identify	identify	VERB
ct-12609	160	29	the	the	DET
ct-12609	160	30	vast	vast	ADJ
ct-12609	160	31	majority	majority	NOUN
ct-12609	160	32	of	of	ADP
ct-12609	160	33	mares	mare	NOUN
ct-12609	160	34	.	.	PUNCT
ct-12609	161	1	a	a	DET
ct-12609	161	2	501	501	NUM
ct-12609	161	3	strict	strict	ADJ
ct-12609	161	4	exercise	exercise	NOUN
ct-12609	161	5	regimen	regiman	NOUN
ct-12609	161	6	plus	plus	CCONJ
ct-12609	161	7	removal	removal	NOUN
ct-12609	161	8	of	of	ADP
ct-12609	161	9	feed	feed	NOUN
ct-12609	161	10	stuffs	stuff	VERB
ct-12609	161	11	rich	rich	ADJ
ct-12609	161	12	in	in	ADP
ct-12609	161	13	carbohydrates	carbohydrate	NOUN
ct-12609	161	14	from	from	ADP
ct-12609	161	15	the	the	DET
ct-12609	161	16	diet	diet	NOUN
ct-12609	161	17	and	and	CCONJ
ct-12609	161	18	supplementation	supplementation	NOUN
ct-12609	161	19	with	with	ADP
ct-12609	161	20	thyroid	thyroid	NOUN
ct-12609	161	21	hormone	hormone	NOUN
ct-12609	161	22	and/or	and/or	CCONJ
ct-12609	161	23	pergolide	pergolide	NOUN
ct-12609	161	24	should	should	AUX
ct-12609	161	25	improve	improve	VERB
ct-12609	161	26	fertility	fertility	NOUN
ct-12609	161	27	in	in	ADP
ct-12609	161	28	affected	affect	VERB
ct-12609	161	29	mares	mare	NOUN
ct-12609	161	30	.	.	PUNCT
ct-12609	162	1	references	reference	NOUN
ct-12609	162	2	1	1	NUM
ct-12609	162	3	.	.	PUNCT
ct-12609	162	4	donaldson	donaldson	PROPN
ct-12609	162	5	mt	mt	PROPN
ct-12609	162	6	,	,	PUNCT
ct-12609	162	7	mcdonell	mcdonell	PROPN
ct-12609	162	8	sm	sm	PROPN
ct-12609	162	9	,	,	PUNCT
ct-12609	162	10	schanbaucher	schanbaucher	ADJ
ct-12609	162	11	bj	bj	VERB
ct-12609	162	12	,	,	PUNCT
ct-12609	162	13	et	et	PROPN
ct-12609	162	14	al	al	PROPN
ct-12609	162	15	:	:	PUNCT
ct-12609	162	16	variation	variation	NOUN
ct-12609	162	17	in	in	ADP
ct-12609	162	18	plasma	plasma	NOUN
ct-12609	162	19	adrenococorticotropic	adrenococorticotropic	ADJ
ct-12609	162	20	hormone	hormone	NOUN
ct-12609	162	21	concentration	concentration	NOUN
ct-12609	162	22	and	and	CCONJ
ct-12609	162	23	dexametasone	dexametasone	NOUN
ct-12609	162	24	suppression	suppression	NOUN
ct-12609	162	25	tests	test	NOUN
ct-12609	162	26	results	result	VERB
ct-12609	162	27	with	with	ADP
ct-12609	162	28	season	season	NOUN
ct-12609	162	29	,	,	PUNCT
ct-12609	162	30	age	age	NOUN
ct-12609	162	31	,	,	PUNCT
ct-12609	162	32	and	and	CCONJ
ct-12609	162	33	sex	sex	NOUN
ct-12609	162	34	in	in	ADP
ct-12609	162	35	healthy	healthy	ADJ
ct-12609	162	36	ponies	pony	NOUN
ct-12609	162	37	and	and	CCONJ
ct-12609	162	38	horses	horse	NOUN
ct-12609	162	39	.	.	PUNCT
ct-12609	163	1	j	j	PROPN
ct-12609	163	2	vet	vet	NOUN
ct-12609	163	3	int	int	NOUN
ct-12609	163	4	med	me	VERB
ct-12609	163	5	2005;19:217	2005;19:217	NUM
ct-12609	163	6	-	-	SYM
ct-12609	163	7	222	222	NUM
ct-12609	163	8	.	.	NOUN
ct-12609	164	1	2	2	NUM
ct-12609	164	2	.	.	X
ct-12609	164	3	johnson	johnson	PROPN
ct-12609	164	4	pj	pj	PROPN
ct-12609	164	5	,	,	PUNCT
ct-12609	164	6	ganjam	ganjam	VERB
ct-12609	164	7	sk	sk	ADP
ct-12609	164	8	,	,	PUNCT
ct-12609	164	9	turk	turk	PROPN
ct-12609	164	10	jr	jr	PROPN
ct-12609	164	11	,	,	PUNCT
ct-12609	164	12	et	et	PROPN
ct-12609	164	13	al	al	PROPN
ct-12609	164	14	:	:	PUNCT
ct-12609	164	15	obesity	obesity	NOUN
ct-12609	164	16	paradigm	paradigm	NOUN
ct-12609	164	17	:	:	PUNCT
ct-12609	164	18	an	an	DET
ct-12609	164	19	introduction	introduction	NOUN
ct-12609	164	20	to	to	ADP
ct-12609	164	21	the	the	DET
ct-12609	164	22	emerging	emerge	VERB
ct-12609	164	23	discipline	discipline	NOUN
ct-12609	164	24	of	of	ADP
ct-12609	164	25	adipobiology	adipobiology	NOUN
ct-12609	164	26	.	.	PUNCT
ct-12609	165	1	proc	proc	PROPN
ct-12609	165	2	annu	annu	PROPN
ct-12609	165	3	conv	conv	PROPN
ct-12609	165	4	am	am	PROPN
ct-12609	165	5	assoc	assoc	PROPN
ct-12609	165	6	equine	equine	PROPN
ct-12609	165	7	pract	pract	PROPN
ct-12609	165	8	2006;4150	2006;4150	NUM
ct-12609	165	9	.	.	PUNCT
ct-12609	166	1	3	3	X
ct-12609	166	2	.	.	X
ct-12609	166	3	equine	equine	NOUN
ct-12609	166	4	metabolic	metabolic	NOUN
ct-12609	166	5	syndrome	syndrome	NOUN
ct-12609	166	6	.	.	PUNCT
ct-12609	167	1	j	j	PROPN
ct-12609	167	2	eq	eq	PROPN
ct-12609	167	3	vet	vet	PROPN
ct-12609	167	4	sci	sci	PROPN
ct-12609	167	5	2003;23:373	2003;23:373	PROPN
ct-12609	167	6	-	-	SYM
ct-12609	167	7	374	374	NUM
ct-12609	167	8	.	.	NOUN
ct-12609	167	9	4	4	NUM
ct-12609	167	10	.	.	X
ct-12609	167	11	frank	frank	PROPN
ct-12609	167	12	n	n	CCONJ
ct-12609	167	13	:	:	PUNCT
ct-12609	167	14	therapeutics	therapeutic	NOUN
ct-12609	167	15	in	in	ADP
ct-12609	167	16	practice	practice	NOUN
ct-12609	167	17	:	:	PUNCT
ct-12609	167	18	managing	manage	VERB
ct-12609	167	19	equine	equine	NOUN
ct-12609	167	20	metabolic	metabolic	NOUN
ct-12609	167	21	syndrome	syndrome	NOUN
ct-12609	167	22	.	.	PUNCT
ct-12609	168	1	compend	compend	VERB
ct-12609	168	2	equine	equine	NOUN
ct-12609	168	3	2008;3:348	2008;3:348	PROPN
ct-12609	168	4	-	-	SYM
ct-12609	168	5	355	355	NUM
ct-12609	168	6	.	.	PUNCT
ct-12609	169	1	5	5	NUM
ct-12609	169	2	.	.	X
ct-12609	169	3	treiber	treiber	PROPN
ct-12609	169	4	kh	kh	PROPN
ct-12609	169	5	,	,	PUNCT
ct-12609	169	6	kronfeld	kronfeld	VERB
ct-12609	169	7	ds	ds	PROPN
ct-12609	169	8	,	,	PUNCT
ct-12609	169	9	hess	hess	PROPN
ct-12609	169	10	tm	tm	PROPN
ct-12609	169	11	,	,	PUNCT
ct-12609	169	12	et	et	PROPN
ct-12609	169	13	al	al	PROPN
ct-12609	169	14	:	:	PUNCT
ct-12609	169	15	evaluation	evaluation	NOUN
ct-12609	169	16	of	of	ADP
ct-12609	169	17	genetic	genetic	ADJ
ct-12609	169	18	and	and	CCONJ
ct-12609	169	19	metabolic	metabolic	NOUN
ct-12609	169	20	predisposition	predisposition	NOUN
ct-12609	169	21	and	and	CCONJ
ct-12609	169	22	nutritional	nutritional	ADJ
ct-12609	169	23	risk	risk	NOUN
ct-12609	169	24	factors	factor	NOUN
ct-12609	169	25	for	for	ADP
ct-12609	169	26	pasture	pasture	NOUN
ct-12609	169	27	associated	associate	VERB
ct-12609	169	28	laminitis	laminitis	NOUN
ct-12609	169	29	in	in	ADP
ct-12609	169	30	ponies	pony	NOUN
ct-12609	169	31	.	.	PUNCT
ct-12609	170	1	j	j	PROPN
ct-12609	170	2	am	be	AUX
ct-12609	170	3	vet	vet	NOUN
ct-12609	170	4	med	med	ADJ
ct-12609	170	5	assoc	assoc	PROPN
ct-12609	170	6	2006	2006	NUM
ct-12609	170	7	;	;	PUNCT
ct-12609	170	8	228	228	NUM
ct-12609	170	9	:	:	PUNCT
ct-12609	170	10	538	538	NUM
ct-12609	170	11	-	-	SYM
ct-12609	170	12	1545	1545	NUM
ct-12609	170	13	.	.	PUNCT
ct-12609	171	1	6	6	NUM
ct-12609	171	2	.	.	X
ct-12609	171	3	frank	frank	PROPN
ct-12609	171	4	n	n	CCONJ
ct-12609	171	5	:	:	PUNCT
ct-12609	171	6	insulin	insulin	NOUN
ct-12609	171	7	resistance	resistance	NOUN
ct-12609	171	8	in	in	ADP
ct-12609	171	9	the	the	DET
ct-12609	171	10	horse	horse	NOUN
ct-12609	171	11	.	.	PUNCT
ct-12609	172	1	proc	proc	PROPN
ct-12609	172	2	annu	annu	PROPN
ct-12609	172	3	conv	conv	PROPN
ct-12609	172	4	am	am	PROPN
ct-12609	172	5	assoc	assoc	PROPN
ct-12609	172	6	equine	equine	PROPN
ct-12609	172	7	pract	pract	PROPN
ct-12609	172	8	2006;51	2006;51	PROPN
ct-12609	172	9	-	-	SYM
ct-12609	172	10	54	54	NUM
ct-12609	172	11	.	.	PUNCT
ct-12609	173	1	7	7	X
ct-12609	173	2	.	.	X
ct-12609	173	3	douglas	douglas	PROPN
ct-12609	173	4	rh	rh	PROPN
ct-12609	173	5	:	:	PUNCT
ct-12609	173	6	endocrine	endocrine	NOUN
ct-12609	173	7	assessment	assessment	NOUN
ct-12609	173	8	and	and	CCONJ
ct-12609	173	9	management	management	NOUN
ct-12609	173	10	of	of	ADP
ct-12609	173	11	insulin	insulin	NOUN
ct-12609	173	12	resistance	resistance	NOUN
ct-12609	173	13	and	and	CCONJ
ct-12609	173	14	ppid	ppid	NOUN
ct-12609	173	15	.	.	PUNCT
ct-12609	174	1	proc	proc	NOUN
ct-12609	174	2	primer	primer	NOUN
ct-12609	174	3	congreso	congreso	VERB
ct-12609	174	4	argentino	argentino	NOUN
ct-12609	174	5	de	de	X
ct-12609	174	6	reproduccion	reproduccion	PROPN
ct-12609	174	7	equina	equina	PROPN
ct-12609	174	8	2009;81	2009;81	PROPN
ct-12609	174	9	-	-	PUNCT
ct-12609	174	10	83	83	NUM
ct-12609	174	11	.	.	PUNCT
ct-12609	175	1	502	502	NUM
ct-12609	175	2	8	8	NUM
ct-12609	175	3	.	.	PUNCT
ct-12609	176	1	mcfarlane	mcfarlane	PROPN
ct-12609	176	2	d	d	NOUN
ct-12609	176	3	:	:	PUNCT
ct-12609	176	4	diagnosing	diagnose	VERB
ct-12609	176	5	pituitary	pituitary	ADJ
ct-12609	176	6	pars	par	NOUN
ct-12609	176	7	intermedia	intermedia	PROPN
ct-12609	176	8	dysfunction	dysfunction	NOUN
ct-12609	176	9	.	.	PUNCT
ct-12609	177	1	compend	compend	VERB
ct-12609	177	2	equine	equine	NOUN
ct-12609	177	3	2007;2:208	2007;2:208	NUM
ct-12609	177	4	-	-	SYM
ct-12609	177	5	213	213	NUM
ct-12609	177	6	.	.	NOUN
ct-12609	178	1	9	9	NUM
ct-12609	178	2	.	.	X
ct-12609	179	1	mcfarlane	mcfarlane	PROPN
ct-12609	179	2	d	d	NOUN
ct-12609	179	3	:	:	PUNCT
ct-12609	179	4	role	role	NOUN
ct-12609	179	5	of	of	ADP
ct-12609	179	6	equine	equine	NOUN
ct-12609	179	7	hypothalamic	hypothalamic	ADJ
ct-12609	179	8	-	-	PUNCT
ct-12609	179	9	pituitary	pituitary	ADJ
ct-12609	179	10	pars	par	NOUN
ct-12609	179	11	intermedia	intermedia	PROPN
ct-12609	179	12	axis	axis	PROPN
ct-12609	179	13	in	in	ADP
ct-12609	179	14	health	health	NOUN
ct-12609	179	15	and	and	CCONJ
ct-12609	179	16	disease	disease	NOUN
ct-12609	179	17	.	.	PUNCT
ct-12609	180	1	proc	proc	PROPN
ct-12609	180	2	annu	annu	PROPN
ct-12609	180	3	conv	conv	PROPN
ct-12609	180	4	am	am	PROPN
ct-12609	180	5	assoc	assoc	PROPN
ct-12609	180	6	equine	equine	PROPN
ct-12609	180	7	pract	pract	PROPN
ct-12609	180	8	2006;55	2006;55	PROPN
ct-12609	180	9	-	-	SYM
ct-12609	180	10	59	59	NUM
ct-12609	180	11	.	.	PUNCT
ct-12609	181	1	10	10	NUM
ct-12609	181	2	.	.	PUNCT
ct-12609	182	1	schott	schott	PROPN
ct-12609	182	2	hc	hc	PROPN
ct-12609	182	3	:	:	PUNCT
ct-12609	182	4	pituitary	pituitary	ADJ
ct-12609	182	5	pars	par	NOUN
ct-12609	182	6	intermedia	intermedia	PROPN
ct-12609	182	7	dysfunction	dysfunction	NOUN
ct-12609	182	8	:	:	PUNCT
ct-12609	182	9	challenges	challenge	NOUN
ct-12609	182	10	of	of	ADP
ct-12609	182	11	diagnosis	diagnosis	NOUN
ct-12609	182	12	and	and	CCONJ
ct-12609	182	13	treatment	treatment	NOUN
ct-12609	182	14	.	.	PUNCT
ct-12609	183	1	proc	proc	PROPN
ct-12609	183	2	annu	annu	PROPN
ct-12609	183	3	conv	conv	PROPN
ct-12609	183	4	am	am	PROPN
ct-12609	183	5	assoc	assoc	PROPN
ct-12609	183	6	equine	equine	PROPN
ct-12609	183	7	pract	pract	PROPN
ct-12609	183	8	2006;60	2006;60	PROPN
ct-12609	183	9	-	-	SYM
ct-12609	183	10	73	73	NUM
ct-12609	183	11	.	.	PUNCT
ct-12609	184	1	11	11	NUM
ct-12609	184	2	.	.	X
ct-12609	185	1	pallaske	pallaske	PROPN
ct-12609	185	2	g	g	NOUN
ct-12609	185	3	:	:	PUNCT
ct-12609	185	4	sur	sur	PROPN
ct-12609	185	5	kasuistik	kasuistik	PROPN
ct-12609	185	6	seltnere	seltnere	PROPN
ct-12609	185	7	geschwülste	geschwülste	NOUN
ct-12609	185	8	bei	bei	PROPN
ct-12609	185	9	den	den	NOUN
ct-12609	185	10	haustieren	haustieren	NOUN
ct-12609	185	11	.	.	PUNCT
ct-12609	186	1	z	z	NOUN
ct-12609	186	2	krebsforsch	krebsforsch	PROPN
ct-12609	186	3	1932	1932	NUM
ct-12609	186	4	;	;	PUNCT
ct-12609	186	5	36:342–353	36:342–353	NUM
ct-12609	186	6	.	.	PUNCT
ct-12609	187	1	12	12	NUM
ct-12609	187	2	.	.	PUNCT
ct-12609	188	1	feldman	feldman	PROPN
ct-12609	188	2	ec	ec	PROPN
ct-12609	188	3	,	,	PUNCT
ct-12609	188	4	nelson	nelson	PROPN
ct-12609	188	5	rw	rw	PROPN
ct-12609	188	6	:	:	PUNCT
ct-12609	188	7	hyperadrenocorticism	hyperadrenocorticism	NOUN
ct-12609	188	8	.	.	PUNCT
ct-12609	189	1	in	in	ADP
ct-12609	189	2	:	:	PUNCT
ct-12609	189	3	canine	canine	VERB
ct-12609	189	4	and	and	CCONJ
ct-12609	189	5	feline	feline	ADJ
ct-12609	189	6	endocrinology	endocrinology	NOUN
ct-12609	189	7	and	and	CCONJ
ct-12609	189	8	reproduction	reproduction	NOUN
ct-12609	189	9	.	.	PUNCT
ct-12609	190	1	philadelphia	philadelphia	PROPN
ct-12609	190	2	:	:	PUNCT
ct-12609	190	3	wb	wb	PROPN
ct-12609	190	4	saunders	saunder	NOUN
ct-12609	190	5	;	;	PUNCT
ct-12609	190	6	1987	1987	NUM
ct-12609	190	7	.	.	PUNCT
ct-12609	191	1	p.	p.	NOUN
ct-12609	191	2	137	137	NUM
ct-12609	191	3	-	-	SYM
ct-12609	191	4	186	186	NUM
ct-12609	191	5	.	.	NOUN
ct-12609	191	6	13	13	NUM
ct-12609	191	7	.	.	X
ct-12609	192	1	castro	castro	PROPN
ct-12609	192	2	acuña	acuña	PROPN
ct-12609	192	3	v	v	PROPN
ct-12609	192	4	,	,	PUNCT
ct-12609	192	5	martinez	martinez	PROPN
ct-12609	192	6	-	-	PUNCT
ct-12609	192	7	martinez	martinez	PROPN
ct-12609	192	8	l	l	PROPN
ct-12609	192	9	,	,	PUNCT
ct-12609	192	10	cravioto	cravioto	NOUN
ct-12609	192	11	m	m	PROPN
ct-12609	192	12	:	:	PUNCT
ct-12609	192	13	.	.	PUNCT
ct-12609	193	1	resistencia	resistencia	PROPN
ct-12609	193	2	a	a	DET
ct-12609	193	3	la	la	X
ct-12609	193	4	insulin	insulin	PROPN
ct-12609	193	5	en	en	PROPN
ct-12609	193	6	el	el	PROPN
ct-12609	193	7	syndrome	syndrome	PROPN
ct-12609	193	8	de	de	X
ct-12609	193	9	ovaries	ovary	NOUN
ct-12609	193	10	poliquisticos	poliquistico	NOUN
ct-12609	193	11	.	.	PUNCT
ct-12609	194	1	rev	rev	PROPN
ct-12609	194	2	inves	inve	VERB
ct-12609	194	3	clin	clin	PROPN
ct-12609	194	4	2004;56:763	2004;56:763	PROPN
ct-12609	194	5	-	-	SYM
ct-12609	194	6	772	772	NUM
ct-12609	194	7	.	.	PUNCT
ct-12609	195	1	14	14	NUM
ct-12609	195	2	.	.	PUNCT
ct-12609	196	1	mcfarlane	mcfarlane	PROPN
ct-12609	196	2	d	d	PROPN
ct-12609	196	3	,	,	PUNCT
ct-12609	196	4	dybdal	dybdal	ADJ
ct-12609	196	5	n	n	NUM
ct-12609	196	6	,	,	PUNCT
ct-12609	196	7	donaldson	donaldson	PROPN
ct-12609	196	8	mt	mt	PROPN
ct-12609	196	9	,	,	PUNCT
ct-12609	196	10	et	et	PROPN
ct-12609	196	11	al	al	PROPN
ct-12609	196	12	:	:	PUNCT
ct-12609	196	13	nitration	nitration	NOUN
ct-12609	196	14	and	and	CCONJ
ct-12609	196	15	increase	increase	VERB
ct-12609	196	16	alpha	alpha	NOUN
ct-12609	196	17	-	-	PUNCT
ct-12609	196	18	synuclein	synuclein	NOUN
ct-12609	196	19	expression	expression	NOUN
ct-12609	196	20	associated	associate	VERB
ct-12609	196	21	with	with	ADP
ct-12609	196	22	dopaminergic	dopaminergic	ADJ
ct-12609	196	23	neurodegeneration	neurodegeneration	NOUN
ct-12609	196	24	in	in	ADP
ct-12609	196	25	equine	equine	NOUN
ct-12609	196	26	pituitary	pituitary	ADJ
ct-12609	196	27	pars	par	NOUN
ct-12609	196	28	intermedia	intermedia	PROPN
ct-12609	196	29	dysfunction	dysfunction	NOUN
ct-12609	196	30	.	.	PUNCT
ct-12609	197	1	j	j	PROPN
ct-12609	197	2	neuroendocrinol	neuroendocrinol	NOUN
ct-12609	197	3	2005;17;73	2005;17;73	NUM
ct-12609	197	4	-	-	SYM
ct-12609	197	5	80	80	NUM
ct-12609	197	6	.	.	PUNCT
ct-12609	197	7	15	15	NUM
ct-12609	197	8	.	.	PUNCT
ct-12609	198	1	beech	beech	PROPN
ct-12609	198	2	j	j	PROPN
ct-12609	198	3	,	,	PUNCT
ct-12609	198	4	garcia	garcia	PROPN
ct-12609	198	5	m	m	PROPN
ct-12609	198	6	:	:	PUNCT
ct-12609	198	7	hormonal	hormonal	ADJ
ct-12609	198	8	response	response	NOUN
ct-12609	198	9	to	to	ADP
ct-12609	198	10	thyrotropin	thyrotropin	NOUN
ct-12609	198	11	-	-	PUNCT
ct-12609	198	12	releasing	release	VERB
ct-12609	198	13	hormone	hormone	NOUN
ct-12609	198	14	in	in	ADP
ct-12609	198	15	healthy	healthy	ADJ
ct-12609	198	16	horses	horse	NOUN
ct-12609	198	17	and	and	CCONJ
ct-12609	198	18	in	in	ADP
ct-12609	198	19	horses	horse	NOUN
ct-12609	198	20	with	with	ADP
ct-12609	198	21	pituitary	pituitary	ADJ
ct-12609	198	22	adenomas	adenoma	NOUN
ct-12609	198	23	.	.	PUNCT
ct-12609	199	1	am	be	AUX
ct-12609	199	2	j	j	PROPN
ct-12609	199	3	vet	vet	NOUN
ct-12609	199	4	res	re	NOUN
ct-12609	199	5	1985;46:1941	1985;46:1941	NUM
ct-12609	199	6	-	-	NOUN
ct-12609	199	7	1943	1943	NUM
ct-12609	199	8	.	.	PUNCT
ct-12609	200	1	16	16	NUM
ct-12609	200	2	.	.	PUNCT
ct-12609	200	3	dybdal	dybdal	ADJ
ct-12609	200	4	no	no	PROPN
ct-12609	200	5	,	,	PUNCT
ct-12609	200	6	hargreaves	hargreaves	PROPN
ct-12609	200	7	km	km	PROPN
ct-12609	200	8	,	,	PUNCT
ct-12609	200	9	madigan	madigan	PROPN
ct-12609	200	10	je	je	PROPN
ct-12609	200	11	,	,	PUNCT
ct-12609	200	12	et	et	PROPN
ct-12609	200	13	al	al	PROPN
ct-12609	200	14	:	:	PUNCT
ct-12609	200	15	diagnostic	diagnostic	ADJ
ct-12609	200	16	testing	testing	NOUN
ct-12609	200	17	for	for	ADP
ct-12609	200	18	pituitary	pituitary	ADJ
ct-12609	200	19	pars	par	NOUN
ct-12609	200	20	intermedia	intermedia	PROPN
ct-12609	200	21	dysfunction	dysfunction	NOUN
ct-12609	200	22	in	in	ADP
ct-12609	200	23	the	the	DET
ct-12609	200	24	horse	horse	NOUN
ct-12609	200	25	.	.	PUNCT
ct-12609	201	1	j	j	PROPN
ct-12609	201	2	am	be	AUX
ct-12609	201	3	vet	vet	NOUN
ct-12609	201	4	med	med	ADJ
ct-12609	201	5	assoc	assoc	PROPN
ct-12609	201	6	1994;204:627	1994;204:627	NUM
ct-12609	201	7	-	-	SYM
ct-12609	201	8	632	632	NUM
ct-12609	201	9	.	.	PUNCT
ct-12609	202	1	17	17	NUM
ct-12609	202	2	.	.	PUNCT
ct-12609	203	1	kreiger	kreiger	PROPN
ct-12609	203	2	dt	dt	PROPN
ct-12609	203	3	,	,	PUNCT
ct-12609	203	4	amorosa	amorosa	PROPN
ct-12609	203	5	l	l	PROPN
ct-12609	203	6	,	,	PUNCT
ct-12609	203	7	linick	linick	NOUN
ct-12609	203	8	f	f	NOUN
ct-12609	203	9	:	:	PUNCT
ct-12609	203	10	cyproheptadine	cyproheptadine	NOUN
ct-12609	203	11	-	-	PUNCT
ct-12609	203	12	induced	induce	VERB
ct-12609	203	13	remission	remission	NOUN
ct-12609	203	14	of	of	ADP
ct-12609	203	15	cushing	cushing	NOUN
ct-12609	203	16	’s	’s	PART
ct-12609	203	17	disease	disease	NOUN
ct-12609	203	18	.	.	PUNCT
ct-12609	204	1	n	n	PROPN
ct-12609	204	2	engl	engl	PROPN
ct-12609	204	3	j	j	PROPN
ct-12609	204	4	med	me	VERB
ct-12609	204	5	1975;293:893	1975;293:893	PROPN
ct-12609	204	6	-	-	SYM
ct-12609	204	7	896	896	NUM
ct-12609	204	8	.	.	PUNCT
ct-12609	205	1	503	503	NUM
ct-12609	205	2	18	18	NUM
ct-12609	205	3	.	.	PUNCT
ct-12609	206	1	mcgowan	mcgowan	PROPN
ct-12609	206	2	cm	cm	PROPN
ct-12609	206	3	,	,	PUNCT
ct-12609	206	4	neiger	neiger	NOUN
ct-12609	206	5	r	r	NOUN
ct-12609	206	6	:	:	PUNCT
ct-12609	206	7	efficacy	efficacy	NOUN
ct-12609	206	8	of	of	ADP
ct-12609	206	9	trilostane	trilostane	NOUN
ct-12609	206	10	for	for	ADP
ct-12609	206	11	the	the	DET
ct-12609	206	12	treatment	treatment	NOUN
ct-12609	206	13	of	of	ADP
ct-12609	206	14	equine	equine	NOUN
ct-12609	206	15	cushing	cushing	NOUN
ct-12609	206	16	’s	’s	PART
ct-12609	206	17	syndrome	syndrome	NOUN
ct-12609	206	18	.	.	PUNCT
ct-12609	207	1	equine	equine	PROPN
ct-12609	207	2	vet	vet	PROPN
ct-12609	207	3	j	j	PROPN
ct-12609	207	4	2003;35:414	2003;35:414	NUM
ct-12609	207	5	-	-	SYM
ct-12609	207	6	418	418	NUM
ct-12609	207	7	.	.	PUNCT
ct-12609	208	1	19	19	NUM
ct-12609	208	2	.	.	X
ct-12609	208	3	vick	vick	PROPN
ct-12609	208	4	mm	mm	PROPN
ct-12609	208	5	,	,	PUNCT
ct-12609	208	6	adams	adams	PROPN
ct-12609	208	7	aa	aa	PROPN
ct-12609	208	8	,	,	PUNCT
ct-12609	208	9	murphy	murphy	PROPN
ct-12609	208	10	ba	ba	PROPN
ct-12609	208	11	,	,	PUNCT
ct-12609	208	12	et	et	PROPN
ct-12609	208	13	al	al	PROPN
ct-12609	208	14	:	:	PUNCT
ct-12609	208	15	relationship	relationship	NOUN
ct-12609	208	16	among	among	ADP
ct-12609	208	17	inflammatory	inflammatory	ADJ
ct-12609	208	18	cytokines	cytokine	NOUN
ct-12609	208	19	,	,	PUNCT
ct-12609	208	20	obesity	obesity	NOUN
ct-12609	208	21	,	,	PUNCT
ct-12609	208	22	and	and	CCONJ
ct-12609	208	23	insulin	insulin	NOUN
ct-12609	208	24	sensitivity	sensitivity	NOUN
ct-12609	208	25	in	in	ADP
ct-12609	208	26	the	the	DET
ct-12609	208	27	horse	horse	NOUN
ct-12609	208	28	.	.	PUNCT
ct-12609	209	1	j	j	PROPN
ct-12609	209	2	anim	anim	NOUN
ct-12609	209	3	sci	sci	PROPN
ct-12609	209	4	2007;85:1144	2007;85:1144	NUM
ct-12609	209	5	-	-	PUNCT
ct-12609	209	6	1155	1155	NUM
ct-12609	209	7	.	.	PUNCT
ct-12609	210	1	20	20	NUM
ct-12609	210	2	.	.	X
ct-12609	210	3	horohov	horohov	PROPN
ct-12609	210	4	dw	dw	PROPN
ct-12609	210	5	:	:	PUNCT
ct-12609	210	6	immunosenescence	immunosenescence	NOUN
ct-12609	210	7	and	and	CCONJ
ct-12609	210	8	inflamm	inflamm	NOUN
ct-12609	210	9	-	-	PUNCT
ct-12609	210	10	aging	aging	NOUN
ct-12609	210	11	in	in	ADP
ct-12609	210	12	the	the	DET
ct-12609	210	13	aged	aged	ADJ
ct-12609	210	14	horse	horse	NOUN
ct-12609	210	15	.	.	PUNCT
ct-12609	211	1	in	in	ADP
ct-12609	211	2	:	:	PUNCT
ct-12609	211	3	the	the	DET
ct-12609	211	4	chronically	chronically	ADV
ct-12609	211	5	infertile	infertile	ADJ
ct-12609	211	6	mare	mare	NOUN
ct-12609	211	7	(	(	PUNCT
ct-12609	211	8	abstract	abstract	ADJ
ct-12609	211	9	book	book	NOUN
ct-12609	211	10	)	)	PUNCT
ct-12609	211	11	.	.	PUNCT
ct-12609	212	1	the	the	DET
ct-12609	212	2	havemeyer	havemeyer	PROPN
ct-12609	212	3	foundation	foundation	PROPN
ct-12609	212	4	2008	2008	NUM
ct-12609	212	5	;	;	PUNCT
ct-12609	212	6	page	page	NOUN
ct-12609	212	7	21	21	NUM
ct-12609	212	8	.	.	PUNCT
ct-12609	212	9	21	21	NUM
ct-12609	212	10	.	.	PUNCT
ct-12609	213	1	adams	adams	PROPN
ct-12609	213	2	aa	aa	PROPN
ct-12609	213	3	,	,	PUNCT
ct-12609	213	4	katepalli	katepalli	PROPN
ct-12609	213	5	mp	mp	PROPN
ct-12609	213	6	,	,	PUNCT
ct-12609	213	7	kohler	kohler	PROPN
ct-12609	213	8	k	k	PROPN
ct-12609	213	9	,	,	PUNCT
ct-12609	213	10	et	et	PROPN
ct-12609	213	11	al	al	PROPN
ct-12609	213	12	:	:	PUNCT
ct-12609	213	13	effect	effect	NOUN
ct-12609	213	14	of	of	ADP
ct-12609	213	15	body	body	NOUN
ct-12609	213	16	condition	condition	NOUN
ct-12609	213	17	,	,	PUNCT
ct-12609	213	18	body	body	NOUN
ct-12609	213	19	weight	weight	NOUN
ct-12609	213	20	and	and	CCONJ
ct-12609	213	21	adiposity	adiposity	NOUN
ct-12609	213	22	on	on	ADP
ct-12609	213	23	inflammatory	inflammatory	ADJ
ct-12609	213	24	cytokines	cytokine	NOUN
ct-12609	213	25	responses	response	NOUN
ct-12609	213	26	in	in	ADP
ct-12609	213	27	old	old	ADJ
ct-12609	213	28	horses	horse	NOUN
ct-12609	213	29	.	.	PUNCT
ct-12609	214	1	in	in	ADP
ct-12609	214	2	:	:	PUNCT
ct-12609	214	3	the	the	DET
ct-12609	214	4	chronically	chronically	ADV
ct-12609	214	5	infertile	infertile	ADJ
ct-12609	214	6	mare	mare	NOUN
ct-12609	214	7	(	(	PUNCT
ct-12609	214	8	abstract	abstract	ADJ
ct-12609	214	9	book	book	NOUN
ct-12609	214	10	)	)	PUNCT
ct-12609	214	11	.	.	PUNCT
ct-12609	215	1	the	the	DET
ct-12609	215	2	havemeyer	havemeyer	PROPN
ct-12609	215	3	foundation	foundation	PROPN
ct-12609	215	4	2008	2008	NUM
ct-12609	215	5	;	;	PUNCT
ct-12609	215	6	page	page	NOUN
ct-12609	215	7	22	22	NUM
ct-12609	215	8	.	.	PUNCT
ct-12609	216	1	22	22	NUM
ct-12609	216	2	.	.	PUNCT
ct-12609	217	1	sattar	sattar	PROPN
ct-12609	217	2	n	n	PROPN
ct-12609	217	3	,	,	PUNCT
ct-12609	217	4	hopkinson	hopkinson	PROPN
ct-12609	217	5	ze	ze	PROPN
ct-12609	217	6	,	,	PUNCT
ct-12609	217	7	greer	greer	PROPN
ct-12609	217	8	ia	ia	PROPN
ct-12609	217	9	.	.	PROPN
ct-12609	217	10	insulin	insulin	NOUN
ct-12609	217	11	sensitizing	sensitize	VERB
ct-12609	217	12	agents	agent	NOUN
ct-12609	217	13	in	in	ADP
ct-12609	217	14	polycystic	polycystic	ADJ
ct-12609	217	15	ovary	ovary	ADJ
ct-12609	217	16	syndrome	syndrome	NOUN
ct-12609	217	17	.	.	PUNCT
ct-12609	218	1	lancet	lancet	PROPN
ct-12609	218	2	1998;351:305	1998;351:305	NUM
ct-12609	218	3	-	-	SYM
ct-12609	218	4	306	306	NUM
ct-12609	218	5	.	.	PUNCT
ct-12609	218	6	23	23	NUM
ct-12609	218	7	.	.	PUNCT
ct-12609	219	1	vick	vick	PROPN
ct-12609	219	2	mm	mm	PROPN
ct-12609	219	3	,	,	PUNCT
ct-12609	219	4	sessions	sessions	PROPN
ct-12609	219	5	dr	dr	PROPN
ct-12609	219	6	,	,	PUNCT
ct-12609	219	7	murphy	murphy	PROPN
ct-12609	219	8	ba	ba	PROPN
ct-12609	219	9	,	,	PUNCT
ct-12609	219	10	et	et	PROPN
ct-12609	219	11	al	al	PROPN
ct-12609	219	12	:	:	PUNCT
ct-12609	219	13	obesity	obesity	NOUN
ct-12609	219	14	is	be	AUX
ct-12609	219	15	associated	associate	VERB
ct-12609	219	16	with	with	ADP
ct-12609	219	17	altered	altered	ADJ
ct-12609	219	18	metabolic	metabolic	NOUN
ct-12609	219	19	and	and	CCONJ
ct-12609	219	20	reproductive	reproductive	ADJ
ct-12609	219	21	activity	activity	NOUN
ct-12609	219	22	in	in	ADP
ct-12609	219	23	the	the	DET
ct-12609	219	24	mare	mare	NOUN
ct-12609	219	25	:	:	PUNCT
ct-12609	219	26	effect	effect	NOUN
ct-12609	219	27	of	of	ADP
ct-12609	219	28	metformin	metformin	NOUN
ct-12609	219	29	on	on	ADP
ct-12609	219	30	insulin	insulin	NOUN
ct-12609	219	31	sensitivity	sensitivity	NOUN
ct-12609	219	32	and	and	CCONJ
ct-12609	219	33	reproductive	reproductive	ADJ
ct-12609	219	34	cyclicity	cyclicity	NOUN
ct-12609	219	35	.	.	PUNCT
ct-12609	220	1	reprod	reprod	PROPN
ct-12609	220	2	fertil	fertil	PROPN
ct-12609	220	3	dev	dev	PROPN
ct-12609	220	4	2006;18:609	2006;18:609	PROPN
ct-12609	220	5	-	-	SYM
ct-12609	220	6	617	617	NUM
ct-12609	220	7	.	.	NUM
ct-12609	221	1	24	24	NUM
ct-12609	221	2	.	.	PUNCT
ct-12609	222	1	fitzgerald	fitzgerald	PROPN
ct-12609	222	2	bp	bp	PROPN
ct-12609	222	3	,	,	PUNCT
ct-12609	222	4	reedy	reedy	VERB
ct-12609	222	5	se	se	NOUN
ct-12609	222	6	,	,	PUNCT
ct-12609	222	7	sessions	sessions	PROPN
ct-12609	222	8	dr	dr	PROPN
ct-12609	222	9	,	,	PUNCT
ct-12609	222	10	et	et	PROPN
ct-12609	222	11	al	al	PROPN
ct-12609	222	12	:	:	PUNCT
ct-12609	222	13	potential	potential	ADJ
ct-12609	222	14	signals	signal	NOUN
ct-12609	222	15	mediating	mediate	VERB
ct-12609	222	16	the	the	DET
ct-12609	222	17	maintenance	maintenance	NOUN
ct-12609	222	18	of	of	ADP
ct-12609	222	19	reproductive	reproductive	ADJ
ct-12609	222	20	activity	activity	NOUN
ct-12609	222	21	during	during	ADP
ct-12609	222	22	the	the	DET
ct-12609	222	23	non	non	ADJ
ct-12609	222	24	-	-	ADJ
ct-12609	222	25	breeding	breeding	ADJ
ct-12609	222	26	season	season	NOUN
ct-12609	222	27	of	of	ADP
ct-12609	222	28	the	the	DET
ct-12609	222	29	mare	mare	NOUN
ct-12609	222	30	.	.	PUNCT
ct-12609	223	1	reprod	reprod	PROPN
ct-12609	223	2	suppl	suppl	PROPN
ct-12609	223	3	2002;59:115	2002;59:115	PROPN
ct-12609	223	4	-	-	SYM
ct-12609	223	5	129	129	NUM
ct-12609	223	6	.	.	PUNCT
ct-12609	224	1	25	25	NUM
ct-12609	224	2	.	.	X
ct-12609	224	3	gentry	gentry	NOUN
ct-12609	224	4	lr	lr	PROPN
ct-12609	224	5	,	,	PUNCT
ct-12609	224	6	thompson	thompson	PROPN
ct-12609	224	7	dl	dl	PROPN
ct-12609	224	8	,	,	PUNCT
ct-12609	224	9	gentry	gentry	NOUN
ct-12609	224	10	gt	gt	PROPN
ct-12609	224	11	,	,	PUNCT
ct-12609	224	12	et	et	PROPN
ct-12609	224	13	al	al	PROPN
ct-12609	224	14	:	:	PUNCT
ct-12609	224	15	the	the	DET
ct-12609	224	16	relationship	relationship	NOUN
ct-12609	224	17	between	between	ADP
ct-12609	224	18	body	body	NOUN
ct-12609	224	19	condition	condition	NOUN
ct-12609	224	20	,	,	PUNCT
ct-12609	224	21	leptin	leptin	NOUN
ct-12609	224	22	,	,	PUNCT
ct-12609	224	23	and	and	CCONJ
ct-12609	224	24	reproductive	reproductive	ADJ
ct-12609	224	25	and	and	CCONJ
ct-12609	224	26	hormonal	hormonal	ADJ
ct-12609	224	27	characteristics	characteristic	NOUN
ct-12609	224	28	of	of	ADP
ct-12609	224	29	mares	mare	NOUN
ct-12609	224	30	during	during	ADP
ct-12609	224	31	during	during	ADP
ct-12609	224	32	the	the	DET
ct-12609	224	33	seasonal	seasonal	ADJ
ct-12609	224	34	anovulatory	anovulatory	NOUN
ct-12609	224	35	period	period	NOUN
ct-12609	224	36	.	.	PUNCT
ct-12609	225	1	j	j	PROPN
ct-12609	225	2	anim	anim	NOUN
ct-12609	225	3	sci	sci	PROPN
ct-12609	225	4	2002;80:2695	2002;80:2695	PROPN
ct-12609	225	5	-	-	PUNCT
ct-12609	225	6	2703	2703	NUM
ct-12609	225	7	.	.	PUNCT
ct-12609	226	1	26	26	NUM
ct-12609	226	2	.	.	PUNCT
ct-12609	226	3	fitzgerald	fitzgerald	PROPN
ct-12609	226	4	bp	bp	PROPN
ct-12609	226	5	,	,	PUNCT
ct-12609	226	6	sessions	sessions	PROPN
ct-12609	226	7	dr	dr	PROPN
ct-12609	226	8	,	,	PUNCT
ct-12609	226	9	vick	vick	PROPN
ct-12609	226	10	mm	mm	PROPN
ct-12609	226	11	,	,	PUNCT
ct-12609	226	12	et	et	PROPN
ct-12609	226	13	al	al	PROPN
ct-12609	226	14	:	:	PUNCT
ct-12609	226	15	obesity	obesity	NOUN
ct-12609	226	16	and	and	CCONJ
ct-12609	226	17	reproduction	reproduction	NOUN
ct-12609	226	18	in	in	ADP
ct-12609	226	19	the	the	DET
ct-12609	226	20	mare	mare	NOUN
ct-12609	226	21	.	.	PUNCT
ct-12609	227	1	in	in	ADP
ct-12609	227	2	:	:	PUNCT
ct-12609	227	3	the	the	DET
ct-12609	227	4	chronically	chronically	ADV
ct-12609	227	5	infertile	infertile	ADJ
ct-12609	227	6	mare	mare	NOUN
ct-12609	227	7	(	(	PUNCT
ct-12609	227	8	abstract	abstract	ADJ
ct-12609	227	9	book	book	NOUN
ct-12609	227	10	)	)	PUNCT
ct-12609	227	11	.	.	PUNCT
ct-12609	228	1	the	the	DET
ct-12609	228	2	havemeyer	havemeyer	PROPN
ct-12609	228	3	foundation	foundation	PROPN
ct-12609	228	4	2008	2008	NUM
ct-12609	228	5	;	;	PUNCT
ct-12609	228	6	page	page	NOUN
ct-12609	228	7	23	23	NUM
ct-12609	228	8	.	.	PUNCT
ct-12609	229	1	504	504	NUM
ct-12609	229	2	27	27	NUM
ct-12609	229	3	.	.	PUNCT
ct-12609	230	1	mccue	mccue	PROPN
ct-12609	230	2	pm	pm	PROPN
ct-12609	230	3	,	,	PUNCT
ct-12609	230	4	squires	squires	PROPN
ct-12609	230	5	el	el	PROPN
ct-12609	230	6	.	.	PUNCT
ct-12609	231	1	persistent	persistent	ADJ
ct-12609	231	2	anovulatory	anovulatory	NOUN
ct-12609	231	3	follicles	follicle	NOUN
ct-12609	231	4	in	in	ADP
ct-12609	231	5	the	the	DET
ct-12609	231	6	mare	mare	NOUN
ct-12609	231	7	.	.	PUNCT
ct-12609	232	1	theriogenology	theriogenology	NOUN
ct-12609	232	2	2002;58:541	2002;58:541	NUM
ct-12609	232	3	-	-	SYM
ct-12609	232	4	543	543	NUM
ct-12609	232	5	.	.	PUNCT
ct-12609	232	6	28	28	NUM
ct-12609	232	7	.	.	PUNCT
ct-12609	233	1	mccue	mccue	PROPN
ct-12609	233	2	pm	pm	PROPN
ct-12609	233	3	.	.	PUNCT
ct-12609	234	1	diagnosis	diagnosis	NOUN
ct-12609	234	2	of	of	ADP
ct-12609	234	3	ovarian	ovarian	ADJ
ct-12609	234	4	abnormalities	abnormality	NOUN
ct-12609	234	5	.	.	PUNCT
ct-12609	235	1	in	in	ADP
ct-12609	235	2	:	:	PUNCT
ct-12609	235	3	ball	ball	PROPN
ct-12609	235	4	ba	ba	PROPN
ct-12609	235	5	,	,	PUNCT
ct-12609	235	6	editor	editor	NOUN
ct-12609	235	7	.	.	PUNCT
ct-12609	236	1	recent	recent	ADJ
ct-12609	236	2	advances	advance	NOUN
ct-12609	236	3	in	in	ADP
ct-12609	236	4	equine	equine	NOUN
ct-12609	236	5	reproduction	reproduction	NOUN
ct-12609	236	6	.	.	PUNCT
ct-12609	237	1	international	international	ADJ
ct-12609	237	2	veterinary	veterinary	ADJ
ct-12609	237	3	information	information	NOUN
ct-12609	237	4	service	service	NOUN
ct-12609	237	5	;	;	PUNCT
ct-12609	237	6	2000	2000	NUM
ct-12609	237	7	available	available	ADJ
ct-12609	237	8	from	from	ADP
ct-12609	237	9	:	:	PUNCT
ct-12609	237	10	http://www.ivis.org	http://www.ivis.org	PROPN
ct-12609	237	11	.	.	PUNCT
ct-12609	238	1	29	29	NUM
ct-12609	238	2	.	.	X
ct-12609	238	3	session	session	PROPN
ct-12609	238	4	dr	dr	PROPN
ct-12609	238	5	,	,	PUNCT
ct-12609	238	6	reedy	reedy	PROPN
ct-12609	238	7	,	,	PUNCT
ct-12609	238	8	vick	vick	PROPN
ct-12609	238	9	mm	mm	PROPN
ct-12609	238	10	,	,	PUNCT
ct-12609	238	11	et	et	PROPN
ct-12609	238	12	al	al	PROPN
ct-12609	238	13	:	:	PUNCT
ct-12609	238	14	development	development	NOUN
ct-12609	238	15	of	of	ADP
ct-12609	238	16	a	a	DET
ct-12609	238	17	model	model	NOUN
ct-12609	238	18	for	for	ADP
ct-12609	238	19	inducing	induce	VERB
ct-12609	238	20	transient	transient	ADJ
ct-12609	238	21	insulin	insulin	NOUN
ct-12609	238	22	resistance	resistance	NOUN
ct-12609	238	23	in	in	ADP
ct-12609	238	24	the	the	DET
ct-12609	238	25	mare	mare	NOUN
ct-12609	238	26	:	:	PUNCT
ct-12609	238	27	preliminary	preliminary	ADJ
ct-12609	238	28	implications	implication	NOUN
ct-12609	238	29	regarding	regard	VERB
ct-12609	238	30	the	the	DET
ct-12609	238	31	estrous	estrous	ADJ
ct-12609	238	32	cycle	cycle	NOUN
ct-12609	238	33	.	.	PUNCT
ct-12609	239	1	j	j	PROPN
ct-12609	239	2	anim	anim	NOUN
ct-12609	239	3	sci	sci	PROPN
ct-12609	239	4	2004;82:2321	2004;82:2321	PROPN
ct-12609	239	5	-	-	SYM
ct-12609	239	6	2328	2328	NUM
ct-12609	239	7	.	.	PUNCT
ct-12609	240	1	30	30	NUM
ct-12609	240	2	.	.	PUNCT
ct-12609	241	1	diamanti	diamanti	PROPN
ct-12609	241	2	-	-	ADJ
ct-12609	241	3	kandarakis	kandarakis	ADJ
ct-12609	241	4	e	e	NOUN
ct-12609	241	5	,	,	PUNCT
ct-12609	241	6	bergiele	bergiele	PROPN
ct-12609	241	7	a.	a.	PROPN
ct-12609	241	8	:	:	PUNCT
ct-12609	241	9	the	the	DET
ct-12609	241	10	influence	influence	NOUN
ct-12609	241	11	of	of	ADP
ct-12609	241	12	obesity	obesity	NOUN
ct-12609	241	13	on	on	ADP
ct-12609	241	14	hyperadrenogenism	hyperadrenogenism	NOUN
ct-12609	241	15	and	and	CCONJ
ct-12609	241	16	infertility	infertility	NOUN
ct-12609	241	17	in	in	ADP
ct-12609	241	18	the	the	DET
ct-12609	241	19	female	female	NOUN
ct-12609	241	20	.	.	PUNCT
ct-12609	242	1	obese	obese	PROPN
ct-12609	242	2	rev	rev	VERB
ct-12609	242	3	2001;2:231	2001;2:231	PROPN
ct-12609	242	4	-	-	SYM
ct-12609	242	5	238	238	NUM
ct-12609	242	6	.	.	PUNCT
ct-12609	243	1	31	31	NUM
ct-12609	243	2	.	.	PUNCT
ct-12609	243	3	nestler	nestler	PROPN
ct-12609	243	4	je	je	PROPN
ct-12609	243	5	.	.	PUNCT
ct-12609	243	6	obesity	obesity	NOUN
ct-12609	243	7	,	,	PUNCT
ct-12609	243	8	insulin	insulin	NOUN
ct-12609	243	9	,	,	PUNCT
ct-12609	243	10	sex	sex	NOUN
ct-12609	243	11	steroids	steroid	NOUN
ct-12609	243	12	and	and	CCONJ
ct-12609	243	13	ovulation	ovulation	NOUN
ct-12609	243	14	.	.	PUNCT
ct-12609	244	1	int	int	PROPN
ct-12609	244	2	j	j	PROPN
ct-12609	244	3	obes	obes	PROPN
ct-12609	244	4	relat	relat	PROPN
ct-12609	244	5	metab	metab	ADJ
ct-12609	244	6	disord	disord	NOUN
ct-12609	244	7	2000;24	2000;24	NUM
ct-12609	244	8	:	:	PUNCT
ct-12609	244	9	s71	s71	NOUN
ct-12609	244	10	-	-	PUNCT
ct-12609	244	11	s73	s73	NOUN
ct-12609	244	12	.	.	PUNCT
ct-12609	245	1	32	32	NUM
ct-12609	245	2	.	.	PUNCT
ct-12609	246	1	ginther	ginther	PROPN
ct-12609	246	2	oj	oj	PROPN
ct-12609	246	3	,	,	PUNCT
ct-12609	246	4	gastal	gastal	PROPN
ct-12609	246	5	el	el	PROPN
ct-12609	246	6	,	,	PUNCT
ct-12609	246	7	gastal	gastal	PROPN
ct-12609	246	8	mo	mo	PROPN
ct-12609	246	9	,	,	PUNCT
ct-12609	246	10	et	et	PROPN
ct-12609	246	11	al	al	PROPN
ct-12609	246	12	:	:	PUNCT
ct-12609	246	13	conversion	conversion	NOUN
ct-12609	246	14	of	of	ADP
ct-12609	246	15	a	a	DET
ct-12609	246	16	viable	viable	ADJ
ct-12609	246	17	preovulatory	preovulatory	NOUN
ct-12609	246	18	follicle	follicle	NOUN
ct-12609	246	19	into	into	ADP
ct-12609	246	20	a	a	DET
ct-12609	246	21	hemorrhagic	hemorrhagic	NOUN
ct-12609	246	22	anovulatory	anovulatory	NOUN
ct-12609	246	23	follicle	follicle	NOUN
ct-12609	246	24	in	in	ADP
ct-12609	246	25	mares	mare	NOUN
ct-12609	246	26	.	.	PUNCT
ct-12609	247	1	anim	anim	NOUN
ct-12609	247	2	reprod	reprod	PROPN
ct-12609	247	3	2006;3:29	2006;3:29	PROPN
ct-12609	247	4	-	-	PUNCT
ct-12609	247	5	40	40	NUM
ct-12609	247	6	.	.	PUNCT
ct-12609	247	7	33	33	NUM
ct-12609	247	8	.	.	PUNCT
ct-12609	248	1	session	session	PROPN
ct-12609	248	2	dr	dr	PROPN
ct-12609	248	3	,	,	PUNCT
ct-12609	248	4	vick	vick	PROPN
ct-12609	248	5	mm	mm	PROPN
ct-12609	248	6	,	,	PUNCT
ct-12609	248	7	fitzgerald	fitzgerald	PROPN
ct-12609	248	8	bp	bp	PROPN
ct-12609	248	9	.	.	PUNCT
ct-12609	249	1	expression	expression	NOUN
ct-12609	249	2	of	of	ADP
ct-12609	249	3	mmp-2	mmp-2	NUM
ct-12609	249	4	and	and	CCONJ
ct-12609	249	5	timp	timp	PROPN
ct-12609	249	6	in	in	ADP
ct-12609	249	7	equine	equine	NOUN
ct-12609	249	8	granulosa	granulosa	NOUN
ct-12609	249	9	cells	cell	NOUN
ct-12609	249	10	and	and	CCONJ
ct-12609	249	11	the	the	DET
ct-12609	249	12	impact	impact	NOUN
ct-12609	249	13	of	of	ADP
ct-12609	249	14	elevated	elevated	ADJ
ct-12609	249	15	insulin	insulin	NOUN
ct-12609	249	16	in	in	ADP
ct-12609	249	17	vitro	vitro	X
ct-12609	249	18	.	.	PUNCT
ct-12609	250	1	biol	biol	PROPN
ct-12609	250	2	reprod	reprod	PROPN
ct-12609	250	3	2007;77:156	2007;77:156	PROPN
ct-12609	250	4	.	.	PUNCT
ct-12609	251	1	505	505	NUM
ct-12609	251	2	<	<	X
ct-12609	251	3	<	<	X
ct-12609	251	4	/ascii85encodepages	/ascii85encodepage	NOUN
ct-12609	251	5	false	false	ADJ
ct-12609	251	6	/allowtransparency	/allowtransparency	NOUN
ct-12609	251	7	false	false	ADJ
ct-12609	251	8	/autopositionepsfiles	/autopositionepsfile	NOUN
ct-12609	251	9	true	true	ADJ
ct-12609	251	10	/autorotatepages	/autorotatepage	NOUN
ct-12609	251	11	/all	/all	PUNCT
ct-12609	252	1	/binding	/binding	NOUN
ct-12609	252	2	/left	/left	ADJ
ct-12609	252	3	/calgrayprofile	/calgrayprofile	VERB
ct-12609	252	4	(	(	PUNCT
ct-12609	252	5	dot	dot	NOUN
ct-12609	252	6	gain	gain	NOUN
ct-12609	252	7	20	20	NUM
ct-12609	252	8	%	%	NOUN
ct-12609	252	9	)	)	PUNCT
ct-12609	252	10	/calrgbprofile	/calrgbprofile	PUNCT
ct-12609	253	1	(	(	PUNCT
ct-12609	253	2	srgb	srgb	PROPN
ct-12609	253	3	iec61966	iec61966	NOUN
ct-12609	253	4	-	-	PUNCT
ct-12609	253	5	2.1	2.1	NUM
ct-12609	253	6	)	)	PUNCT
ct-12609	253	7	/calcmykprofile	/calcmykprofile	PUNCT
ct-12609	254	1	(	(	PUNCT
ct-12609	254	2	u.s	u.s	PROPN
ct-12609	254	3	.	.	PROPN
ct-12609	254	4	web	web	NOUN
ct-12609	254	5	coated	coat	VERB
ct-12609	254	6	\050swop\051	\050swop\051	ADJ
ct-12609	254	7	v2	v2	NOUN
ct-12609	254	8	)	)	PUNCT
ct-12609	254	9	/srgbprofile	/srgbprofile	PUNCT
ct-12609	254	10	(	(	PUNCT
ct-12609	254	11	srgb	srgb	PROPN
ct-12609	254	12	iec61966	iec61966	NOUN
ct-12609	254	13	-	-	PUNCT
ct-12609	254	14	2.1	2.1	NUM
ct-12609	254	15	)	)	PUNCT
ct-12609	254	16	/cannotembedfontpolicy	/cannotembedfontpolicy	NOUN
ct-12609	255	1	/warning	/warne	VERB
ct-12609	255	2	/compatibilitylevel	/compatibilitylevel	NOUN
ct-12609	255	3	1.4	1.4	NUM
ct-12609	255	4	/compressobjects	/compressobject	NOUN
ct-12609	256	1	/tags	/tag	NOUN
ct-12609	256	2	/compresspages	/compresspage	NOUN
ct-12609	256	3	false	false	ADJ
ct-12609	256	4	/convertimagestoindexed	/convertimagestoindexed	ADJ
ct-12609	256	5	true	true	ADJ
ct-12609	256	6	/passthroughjpegimages	/passthroughjpegimage	NOUN
ct-12609	256	7	true	true	ADJ
ct-12609	256	8	/createjobticket	/createjobticket	NOUN
ct-12609	256	9	false	false	ADJ
ct-12609	256	10	/defaultrenderingintent	/defaultrenderingintent	NOUN
ct-12609	256	11	/default	/default	PUNCT
ct-12609	256	12	/detectblends	/detectblend	NOUN
ct-12609	257	1	true	true	ADJ
ct-12609	257	2	/detectcurves	/detectcurve	VERB
ct-12609	257	3	0.0000	0.0000	NUM
ct-12609	257	4	/colorconversionstrategy	/colorconversionstrategy	NOUN
ct-12609	257	5	/cmyk	/cmyk	PUNCT
ct-12609	258	1	/dothumbnails	/dothumbnail	VERB
ct-12609	259	1	false	false	ADJ
ct-12609	259	2	/embedallfonts	/embedallfont	NOUN
ct-12609	259	3	true	true	ADJ
ct-12609	259	4	/embedopentype	/embedopentype	PUNCT
ct-12609	259	5	false	false	ADJ
ct-12609	259	6	/parseiccprofilesincomments	/parseiccprofilesincomment	NOUN
ct-12609	259	7	true	true	ADJ
ct-12609	259	8	/embedjoboptions	/embedjoboption	NOUN
ct-12609	259	9	true	true	ADJ
ct-12609	259	10	/dscreportinglevel	/dscreportinglevel	NOUN
ct-12609	259	11	0	0	NUM
ct-12609	259	12	/emitdscwarnings	/emitdscwarning	NOUN
ct-12609	259	13	false	false	ADJ
ct-12609	259	14	/endpage	/endpage	NOUN
ct-12609	259	15	-1	-1	NOUN
ct-12609	259	16	/imagememory	/imagememory	NUM
ct-12609	259	17	1048576	1048576	NUM
ct-12609	259	18	/lockdistillerparams	/lockdistillerparams	NOUN
ct-12609	259	19	false	false	ADJ
ct-12609	259	20	/maxsubsetpct	/maxsubsetpct	ADJ
ct-12609	259	21	100	100	NUM
ct-12609	259	22	/optimize	/optimize	NOUN
ct-12609	259	23	true	true	ADJ
ct-12609	259	24	/opm	/opm	NOUN
ct-12609	259	25	1	1	NUM
ct-12609	259	26	/parsedsccomments	/parsedsccomment	NOUN
ct-12609	259	27	true	true	ADJ
ct-12609	259	28	/parsedsccommentsfordocinfo	/parsedsccommentsfordocinfo	VERB
ct-12609	259	29	true	true	ADJ
ct-12609	259	30	/preservecopypage	/preservecopypage	NOUN
ct-12609	259	31	true	true	ADJ
ct-12609	259	32	/preservedicmykvalues	/preservedicmykvalue	NOUN
ct-12609	259	33	true	true	ADJ
ct-12609	259	34	/preserveepsinfo	/preserveepsinfo	NOUN
ct-12609	259	35	true	true	ADJ
ct-12609	259	36	/preserveflatness	/preserveflatness	INTJ
ct-12609	259	37	false	false	ADJ
ct-12609	259	38	/preservehalftoneinfo	/preservehalftoneinfo	PUNCT
ct-12609	259	39	false	false	ADJ
ct-12609	259	40	/preserveopicomments	/preserveopicomment	NOUN
ct-12609	259	41	false	false	ADJ
ct-12609	259	42	/preserveoverprintsettings	/preserveoverprintsetting	NOUN
ct-12609	259	43	true	true	ADJ
ct-12609	259	44	/startpage	/startpage	NOUN
ct-12609	259	45	1	1	NUM
ct-12609	259	46	/subsetfonts	/subsetfont	NOUN
ct-12609	259	47	true	true	ADJ
ct-12609	259	48	/transferfunctioninfo	/transferfunctioninfo	PUNCT
ct-12609	259	49	/apply	/apply	PUNCT
ct-12609	259	50	/ucrandbginfo	/ucrandbginfo	PUNCT
ct-12609	260	1	/preserve	/preserve	NOUN
ct-12609	260	2	/useprologue	/useprologue	NOUN
ct-12609	260	3	false	false	ADJ
ct-12609	260	4	/colorsettingsfile	/colorsettingsfile	NOUN
ct-12609	260	5	(	(	PUNCT
ct-12609	260	6	)	)	PUNCT
ct-12609	260	7	/alwaysembed	/alwaysembe	VERB
ct-12609	260	8	[	[	PUNCT
ct-12609	260	9	true	true	ADJ
ct-12609	260	10	]	]	PUNCT
ct-12609	260	11	/neverembed	/neverembed	PUNCT
ct-12609	261	1	[	[	PUNCT
ct-12609	261	2	true	true	ADJ
ct-12609	261	3	]	]	PUNCT
ct-12609	261	4	/antialiascolorimages	/antialiascolorimages	X
ct-12609	261	5	false	false	ADJ
ct-12609	261	6	/cropcolorimages	/cropcolorimages	INTJ
ct-12609	261	7	false	false	ADJ
ct-12609	261	8	/colorimageminresolution	/colorimageminresolution	NOUN
ct-12609	261	9	300	300	NUM
ct-12609	261	10	/colorimageminresolutionpolicy	/colorimageminresolutionpolicy	NOUN
ct-12609	261	11	/ok	/ok	INTJ
ct-12609	261	12	/downsamplecolorimages	/downsamplecolorimage	NOUN
ct-12609	262	1	false	false	ADJ
ct-12609	262	2	/colorimagedownsampletype	/colorimagedownsampletype	NOUN
ct-12609	262	3	/average	/average	NOUN
ct-12609	262	4	/colorimageresolution	/colorimageresolution	NOUN
ct-12609	263	1	300	300	NUM
ct-12609	263	2	/colorimagedepth	/colorimagedepth	PRON
ct-12609	263	3	-1	-1	INTJ
ct-12609	263	4	/colorimagemindownsampledepth	/colorimagemindownsampledepth	SYM
ct-12609	263	5	1	1	NUM
ct-12609	263	6	/colorimagedownsamplethreshold	/colorimagedownsamplethreshold	SYM
ct-12609	263	7	1.50000	1.50000	NUM
ct-12609	263	8	/encodecolorimages	/encodecolorimage	NOUN
ct-12609	263	9	false	false	ADJ
ct-12609	263	10	/colorimagefilter	/colorimagefilter	NOUN
ct-12609	263	11	/dctencode	/dctencode	PUNCT
ct-12609	264	1	/autofiltercolorimages	/autofiltercolorimage	NOUN
ct-12609	264	2	true	true	ADJ
ct-12609	264	3	/colorimageautofilterstrategy	/colorimageautofilterstrategy	PUNCT
ct-12609	264	4	/jpeg	/jpeg	PUNCT
ct-12609	264	5	/coloracsimagedict	/coloracsimagedict	PUNCT
ct-12609	265	1	<	<	X
ct-12609	265	2	<	<	X
ct-12609	265	3	/qfactor	/qfactor	NOUN
ct-12609	266	1	0.76	0.76	NUM
ct-12609	266	2	/hsamples	/hsample	NOUN
ct-12609	267	1	[	[	X
ct-12609	267	2	2	2	NUM
ct-12609	267	3	1	1	NUM
ct-12609	267	4	1	1	NUM
ct-12609	267	5	2	2	NUM
ct-12609	267	6	]	]	PUNCT
ct-12609	267	7	/vsamples	/vsample	NOUN
ct-12609	268	1	[	[	X
ct-12609	268	2	2	2	NUM
ct-12609	268	3	1	1	NUM
ct-12609	268	4	1	1	NUM
ct-12609	268	5	2	2	NUM
ct-12609	268	6	]	]	PUNCT
ct-12609	268	7	>	>	PUNCT
ct-12609	268	8	>	>	X
ct-12609	268	9	/colorimagedict	/colorimagedict	PUNCT
ct-12609	269	1	<	<	X
ct-12609	269	2	<	<	X
ct-12609	269	3	/qfactor	/qfactor	NOUN
ct-12609	269	4	0.15	0.15	NUM
ct-12609	269	5	/hsamples	/hsample	NOUN
ct-12609	270	1	[	[	X
ct-12609	270	2	1	1	NUM
ct-12609	270	3	1	1	NUM
ct-12609	270	4	1	1	NUM
ct-12609	270	5	1	1	NUM
ct-12609	270	6	]	]	PUNCT
ct-12609	270	7	/vsamples	/vsample	NOUN
ct-12609	271	1	[	[	X
ct-12609	271	2	1	1	NUM
ct-12609	271	3	1	1	NUM
ct-12609	271	4	1	1	NUM
ct-12609	271	5	1	1	NUM
ct-12609	271	6	]	]	PUNCT
ct-12609	271	7	>	>	PUNCT
ct-12609	271	8	>	>	X
ct-12609	271	9	/jpeg2000coloracsimagedict	/jpeg2000coloracsimagedict	PUNCT
ct-12609	272	1	<	<	X
ct-12609	272	2	<	<	X
ct-12609	272	3	/tilewidth	/tilewidth	PUNCT
ct-12609	272	4	256	256	NUM
ct-12609	272	5	/tileheight	/tileheight	NUM
ct-12609	272	6	256	256	NUM
ct-12609	272	7	/quality	/quality	NOUN
ct-12609	272	8	30	30	NUM
ct-12609	272	9	>	>	PUNCT
ct-12609	272	10	>	>	X
ct-12609	272	11	/jpeg2000colorimagedict	/jpeg2000colorimagedict	PUNCT
ct-12609	272	12	<	<	X
ct-12609	272	13	<	<	X
ct-12609	272	14	/tilewidth	/tilewidth	PUNCT
ct-12609	272	15	256	256	NUM
ct-12609	272	16	/tileheight	/tileheight	NUM
ct-12609	272	17	256	256	NUM
ct-12609	272	18	/quality	/quality	NOUN
ct-12609	272	19	30	30	NUM
ct-12609	272	20	>	>	PUNCT
ct-12609	272	21	>	>	X
ct-12609	272	22	/antialiasgrayimages	/antialiasgrayimages	X
ct-12609	272	23	false	false	ADJ
ct-12609	272	24	/cropgrayimages	/cropgrayimage	NOUN
ct-12609	272	25	false	false	ADJ
ct-12609	272	26	/grayimageminresolution	/grayimageminresolution	NOUN
ct-12609	272	27	300	300	NUM
ct-12609	272	28	/grayimageminresolutionpolicy	/grayimageminresolutionpolicy	NOUN
ct-12609	273	1	/ok	/ok	ADJ
ct-12609	273	2	/downsamplegrayimages	/downsamplegrayimage	NOUN
ct-12609	274	1	false	false	ADJ
ct-12609	274	2	/grayimagedownsampletype	/grayimagedownsampletype	NOUN
ct-12609	274	3	/average	/average	NOUN
ct-12609	274	4	/grayimageresolution	/grayimageresolution	NOUN
ct-12609	275	1	300	300	NUM
ct-12609	275	2	/grayimagedepth	/grayimagedepth	PUNCT
ct-12609	275	3	-1	-1	PUNCT
ct-12609	275	4	/grayimagemindownsampledepth	/grayimagemindownsampledepth	PUNCT
ct-12609	275	5	2	2	NUM
ct-12609	275	6	/grayimagedownsamplethreshold	/grayimagedownsamplethreshold	NUM
ct-12609	275	7	1.50000	1.50000	NUM
ct-12609	275	8	/encodegrayimages	/encodegrayimage	NOUN
ct-12609	275	9	false	false	ADJ
ct-12609	275	10	/grayimagefilter	/grayimagefilter	NOUN
ct-12609	275	11	/dctencode	/dctencode	PUNCT
ct-12609	276	1	/autofiltergrayimages	/autofiltergrayimages	VERB
ct-12609	276	2	true	true	ADJ
ct-12609	276	3	/grayimageautofilterstrategy	/grayimageautofilterstrategy	INTJ
ct-12609	276	4	/jpeg	/jpeg	PUNCT
ct-12609	276	5	/grayacsimagedict	/grayacsimagedict	PUNCT
ct-12609	277	1	<	<	X
ct-12609	277	2	<	<	X
ct-12609	277	3	/qfactor	/qfactor	NOUN
ct-12609	278	1	0.76	0.76	NUM
ct-12609	278	2	/hsamples	/hsample	NOUN
ct-12609	279	1	[	[	X
ct-12609	279	2	2	2	NUM
ct-12609	279	3	1	1	NUM
ct-12609	279	4	1	1	NUM
ct-12609	279	5	2	2	NUM
ct-12609	279	6	]	]	PUNCT
ct-12609	279	7	/vsamples	/vsample	NOUN
ct-12609	280	1	[	[	X
ct-12609	280	2	2	2	NUM
ct-12609	280	3	1	1	NUM
ct-12609	280	4	1	1	NUM
ct-12609	280	5	2	2	NUM
ct-12609	280	6	]	]	PUNCT
ct-12609	280	7	>	>	PUNCT
ct-12609	280	8	>	>	X
ct-12609	280	9	/grayimagedict	/grayimagedict	PUNCT
ct-12609	281	1	<	<	X
ct-12609	281	2	<	<	X
ct-12609	281	3	/qfactor	/qfactor	NOUN
ct-12609	281	4	0.15	0.15	NUM
ct-12609	281	5	/hsamples	/hsample	NOUN
ct-12609	282	1	[	[	X
ct-12609	282	2	1	1	NUM
ct-12609	282	3	1	1	NUM
ct-12609	282	4	1	1	NUM
ct-12609	282	5	1	1	NUM
ct-12609	282	6	]	]	PUNCT
ct-12609	282	7	/vsamples	/vsample	NOUN
ct-12609	283	1	[	[	X
ct-12609	283	2	1	1	NUM
ct-12609	283	3	1	1	NUM
ct-12609	283	4	1	1	NUM
ct-12609	283	5	1	1	NUM
ct-12609	283	6	]	]	PUNCT
ct-12609	283	7	>	>	X
ct-12609	283	8	>	>	X
ct-12609	283	9	/jpeg2000grayacsimagedict	/jpeg2000grayacsimagedict	PUNCT
ct-12609	284	1	<	<	X
ct-12609	284	2	<	<	X
ct-12609	284	3	/tilewidth	/tilewidth	PUNCT
ct-12609	284	4	256	256	NUM
ct-12609	284	5	/tileheight	/tileheight	NUM
ct-12609	284	6	256	256	NUM
ct-12609	284	7	/quality	/quality	NOUN
ct-12609	284	8	30	30	NUM
ct-12609	284	9	>	>	PUNCT
ct-12609	284	10	>	>	X
ct-12609	284	11	/jpeg2000grayimagedict	/jpeg2000grayimagedict	PUNCT
ct-12609	284	12	<	<	X
ct-12609	284	13	<	<	X
ct-12609	284	14	/tilewidth	/tilewidth	PUNCT
ct-12609	284	15	256	256	NUM
ct-12609	284	16	/tileheight	/tileheight	NUM
ct-12609	284	17	256	256	NUM
ct-12609	284	18	/quality	/quality	NOUN
ct-12609	284	19	30	30	NUM
ct-12609	284	20	>	>	PUNCT
ct-12609	284	21	>	>	X
ct-12609	284	22	/antialiasmonoimages	/antialiasmonoimage	NOUN
ct-12609	284	23	false	false	ADJ
ct-12609	284	24	/cropmonoimages	/cropmonoimage	NOUN
ct-12609	284	25	false	false	ADJ
ct-12609	284	26	/monoimageminresolution	/monoimageminresolution	NOUN
ct-12609	284	27	1200	1200	NUM
ct-12609	284	28	/monoimageminresolutionpolicy	/monoimageminresolutionpolicy	PUNCT
ct-12609	285	1	/ok	/ok	PROPN
ct-12609	285	2	/downsamplemonoimages	/downsamplemonoimage	VERB
ct-12609	286	1	false	false	ADJ
ct-12609	286	2	/monoimagedownsampletype	/monoimagedownsampletype	NOUN
ct-12609	286	3	/average	/average	NOUN
ct-12609	286	4	/monoimageresolution	/monoimageresolution	NOUN
ct-12609	287	1	300	300	NUM
ct-12609	287	2	/monoimagedepth	/monoimagedepth	PRON
ct-12609	287	3	-1	-1	PUNCT
ct-12609	287	4	/monoimagedownsamplethreshold	/monoimagedownsamplethreshold	PUNCT
ct-12609	287	5	1.50000	1.50000	NUM
ct-12609	287	6	/encodemonoimages	/encodemonoimage	NOUN
ct-12609	287	7	false	false	ADJ
ct-12609	287	8	/monoimagefilter	/monoimagefilter	ADP
ct-12609	287	9	/flateencode	/flateencode	PROPN
ct-12609	287	10	/monoimagedict	/monoimagedict	PUNCT
ct-12609	288	1	<	<	X
ct-12609	288	2	<	<	X
ct-12609	288	3	/k	/k	PUNCT
ct-12609	288	4	-1	-1	INTJ
ct-12609	288	5	>	>	PUNCT
ct-12609	288	6	>	>	X
ct-12609	288	7	/allowpsxobjects	/allowpsxobjects	PROPN
ct-12609	288	8	false	false	ADJ
ct-12609	288	9	/checkcompliance	/checkcompliance	NOUN
ct-12609	288	10	[	[	PUNCT
ct-12609	288	11	/none	/none	X
ct-12609	288	12	]	]	PUNCT
ct-12609	288	13	/pdfx1acheck	/pdfx1acheck	PUNCT
ct-12609	288	14	false	false	ADJ
ct-12609	288	15	/pdfx3check	/pdfx3check	PUNCT
ct-12609	288	16	false	false	ADJ
ct-12609	288	17	/pdfxcompliantpdfonly	/pdfxcompliantpdfonly	ADV
ct-12609	288	18	false	false	ADJ
ct-12609	288	19	/pdfxnotrimboxerror	/pdfxnotrimboxerror	NOUN
ct-12609	288	20	true	true	ADJ
ct-12609	288	21	/pdfxtrimboxtomediaboxoffset	/pdfxtrimboxtomediaboxoffset	NOUN
ct-12609	288	22	[	[	PUNCT
ct-12609	288	23	0.00000	0.00000	NUM
ct-12609	288	24	0.00000	0.00000	NUM
ct-12609	288	25	0.00000	0.00000	NUM
ct-12609	288	26	0.00000	0.00000	NUM
ct-12609	288	27	]	]	PUNCT
ct-12609	288	28	/pdfxsetbleedboxtomediabox	/pdfxsetbleedboxtomediabox	PUNCT
ct-12609	289	1	true	true	ADJ
ct-12609	289	2	/pdfxbleedboxtotrimboxoffset	/pdfxbleedboxtotrimboxoffset	PUNCT
ct-12609	289	3	[	[	PUNCT
ct-12609	289	4	0.00000	0.00000	NUM
ct-12609	289	5	0.00000	0.00000	NUM
ct-12609	289	6	0.00000	0.00000	NUM
ct-12609	289	7	0.00000	0.00000	NUM
ct-12609	289	8	]	]	PUNCT
ct-12609	289	9	/pdfxoutputintentprofile	/pdfxoutputintentprofile	PUNCT
ct-12609	290	1	(	(	PUNCT
ct-12609	290	2	)	)	PUNCT
ct-12609	290	3	/pdfxoutputconditionidentifier	/pdfxoutputconditionidentifi	ADJ
ct-12609	290	4	(	(	PUNCT
ct-12609	290	5	)	)	PUNCT
ct-12609	290	6	/pdfxoutputcondition	/pdfxoutputcondition	PRON
ct-12609	290	7	(	(	PUNCT
ct-12609	290	8	)	)	PUNCT
ct-12609	290	9	/pdfxregistryname	/pdfxregistryname	PUNCT
ct-12609	290	10	(	(	PUNCT
ct-12609	290	11	)	)	PUNCT
ct-12609	290	12	/pdfxtrapped	/pdfxtrapped	PUNCT
ct-12609	290	13	/false	/false	INTJ
ct-12609	291	1	/createjdffile	/createjdffile	INTJ
ct-12609	291	2	false	false	ADJ
ct-12609	291	3	/description	/description	NOUN
ct-12609	291	4	<	<	X
ct-12609	291	5	<	<	X
ct-12609	291	6	/enu	/enu	PUNCT
ct-12609	291	7	(	(	PUNCT
ct-12609	291	8	[	[	X
ct-12609	291	9	based	base	VERB
ct-12609	291	10	on	on	ADP
ct-12609	291	11	'	'	PUNCT
ct-12609	291	12	no	no	DET
ct-12609	291	13	compression	compression	NOUN
ct-12609	291	14	'	'	PUNCT
ct-12609	291	15	]	]	PUNCT
ct-12609	292	1	[	[	X
ct-12609	292	2	based	base	VERB
ct-12609	292	3	on	on	ADP
ct-12609	292	4	'	'	PUNCT
ct-12609	292	5	no	no	DET
ct-12609	292	6	compression	compression	NOUN
ct-12609	292	7	wbleeed	wbleeed	NOUN
ct-12609	292	8	'	'	PUNCT
ct-12609	292	9	]	]	PUNCT
ct-12609	293	1	[	[	X
ct-12609	293	2	based	base	VERB
ct-12609	293	3	on	on	ADP
ct-12609	293	4	'	'	PUNCT
ct-12609	293	5	[	[	X
ct-12609	293	6	high	high	ADJ
ct-12609	293	7	quality	quality	NOUN
ct-12609	293	8	print	print	NOUN
ct-12609	293	9	]	]	PUNCT
ct-12609	293	10	'	'	PUNCT
ct-12609	293	11	]	]	PUNCT
ct-12609	293	12	use	use	VERB
ct-12609	293	13	these	these	DET
ct-12609	293	14	settings	setting	NOUN
ct-12609	293	15	to	to	PART
ct-12609	293	16	create	create	VERB
ct-12609	293	17	adobe	adobe	PROPN
ct-12609	293	18	pdf	pdf	NOUN
ct-12609	293	19	documents	document	NOUN
ct-12609	293	20	for	for	ADP
ct-12609	293	21	quality	quality	NOUN
ct-12609	293	22	printing	printing	NOUN
ct-12609	293	23	on	on	ADP
ct-12609	293	24	desktop	desktop	NOUN
ct-12609	293	25	printers	printer	NOUN
ct-12609	293	26	and	and	CCONJ
ct-12609	293	27	proofers	proofer	NOUN
ct-12609	293	28	.	.	PUNCT
ct-12609	294	1	created	create	VERB
ct-12609	294	2	pdf	pdf	NOUN
ct-12609	294	3	documents	document	NOUN
ct-12609	294	4	can	can	AUX
ct-12609	294	5	be	be	AUX
ct-12609	294	6	opened	open	VERB
ct-12609	294	7	with	with	ADP
ct-12609	294	8	acrobat	acrobat	PROPN
ct-12609	294	9	and	and	CCONJ
ct-12609	294	10	adobe	adobe	PROPN
ct-12609	294	11	reader	reader	PROPN
ct-12609	294	12	5.0	5.0	NUM
ct-12609	294	13	and	and	CCONJ
ct-12609	294	14	later	later	ADV
ct-12609	294	15	.	.	PUNCT
ct-12609	294	16	)	)	PUNCT
ct-12609	295	1	>	>	PUNCT
ct-12609	295	2	>	>	X
ct-12609	295	3	/namespace	/namespace	PUNCT
ct-12609	296	1	[	[	PUNCT
ct-12609	296	2	(	(	PUNCT
ct-12609	296	3	adobe	adobe	PROPN
ct-12609	296	4	)	)	PUNCT
ct-12609	296	5	(	(	PUNCT
ct-12609	296	6	common	common	ADJ
ct-12609	296	7	)	)	PUNCT
ct-12609	296	8	(	(	PUNCT
ct-12609	296	9	1.0	1.0	NUM
ct-12609	296	10	)	)	PUNCT
ct-12609	296	11	]	]	PUNCT
ct-12609	297	1	/othernamespaces	/othernamespace	VERB
ct-12609	297	2	[	[	PUNCT
ct-12609	297	3	<	<	X
ct-12609	297	4	<	<	X
ct-12609	297	5	/asreaderspreads	/asreaderspreads	X
ct-12609	297	6	false	false	ADJ
ct-12609	297	7	/cropimagestoframes	/cropimagestoframe	NOUN
ct-12609	297	8	false	false	ADJ
ct-12609	297	9	/errorcontrol	/errorcontrol	NOUN
ct-12609	297	10	/warnandcontinue	/warnandcontinue	PUNCT
ct-12609	298	1	/flattenerignorespreadoverrides	/flattenerignorespreadoverride	NOUN
ct-12609	298	2	false	false	ADJ
ct-12609	298	3	/includeguidesgrids	/includeguidesgrid	NOUN
ct-12609	298	4	false	false	ADJ
ct-12609	298	5	/includenonprinting	/includenonprinting	NOUN
ct-12609	298	6	false	false	ADJ
ct-12609	298	7	/includeslug	/includeslug	INTJ
ct-12609	298	8	false	false	ADJ
ct-12609	298	9	/namespace	/namespace	NOUN
ct-12609	299	1	[	[	PUNCT
ct-12609	299	2	(	(	PUNCT
ct-12609	299	3	adobe	adobe	PROPN
ct-12609	299	4	)	)	PUNCT
ct-12609	299	5	(	(	PUNCT
ct-12609	299	6	indesign	indesign	NOUN
ct-12609	299	7	)	)	PUNCT
ct-12609	299	8	(	(	PUNCT
ct-12609	299	9	4.0	4.0	NUM
ct-12609	299	10	)	)	PUNCT
ct-12609	299	11	]	]	PUNCT
ct-12609	299	12	/omitplacedbitmaps	/omitplacedbitmaps	PUNCT
ct-12609	300	1	false	false	ADJ
ct-12609	300	2	/omitplacedeps	/omitplacedeps	INTJ
ct-12609	300	3	false	false	ADJ
ct-12609	300	4	/omitplacedpdf	/omitplacedpdf	PUNCT
ct-12609	300	5	false	false	ADJ
ct-12609	300	6	/simulateoverprint	/simulateoverprint	NOUN
ct-12609	300	7	/legacy	/legacy	PUNCT
ct-12609	301	1	>	>	PUNCT
ct-12609	301	2	>	>	X
ct-12609	301	3	<	<	X
ct-12609	301	4	<	<	X
ct-12609	301	5	/addbleedmarks	/addbleedmarks	X
ct-12609	301	6	false	false	ADJ
ct-12609	301	7	/addcolorbars	/addcolorbars	INTJ
ct-12609	301	8	false	false	ADJ
ct-12609	301	9	/addcropmarks	/addcropmarks	PUNCT
ct-12609	301	10	false	false	ADJ
ct-12609	301	11	/addpageinfo	/addpageinfo	INTJ
ct-12609	301	12	false	false	ADJ
ct-12609	301	13	/addregmarks	/addregmark	NOUN
ct-12609	301	14	false	false	ADJ
ct-12609	301	15	/bleedoffset	/bleedoffset	NOUN
ct-12609	301	16	[	[	PUNCT
ct-12609	301	17	0	0	NUM
ct-12609	301	18	0	0	NUM
ct-12609	301	19	0	0	NUM
ct-12609	301	20	0	0	NUM
ct-12609	301	21	]	]	PUNCT
ct-12609	302	1	/convertcolors	/convertcolors	DET
ct-12609	302	2	/noconversion	/noconversion	INTJ
ct-12609	302	3	/destinationprofilename	/destinationprofilename	PUNCT
ct-12609	302	4	(	(	PUNCT
ct-12609	302	5	)	)	PUNCT
ct-12609	302	6	/destinationprofileselector	/destinationprofileselector	NOUN
ct-12609	302	7	/na	/na	PUNCT
ct-12609	302	8	/downsample16bitimages	/downsample16bitimage	NOUN
ct-12609	302	9	true	true	ADJ
ct-12609	302	10	/flattenerpreset	/flattenerpreset	PUNCT
ct-12609	303	1	<	<	X
ct-12609	303	2	<	<	X
ct-12609	303	3	/presetselector	/presetselector	X
ct-12609	303	4	/mediumresolution	/mediumresolution	NOUN
ct-12609	303	5	>	>	PUNCT
ct-12609	303	6	>	>	X
ct-12609	303	7	/formelements	/formelement	NOUN
ct-12609	304	1	false	false	ADJ
ct-12609	304	2	/generatestructure	/generatestructure	NOUN
ct-12609	304	3	true	true	ADJ
ct-12609	304	4	/includebookmarks	/includebookmark	NOUN
ct-12609	304	5	false	false	ADJ
ct-12609	304	6	/includehyperlinks	/includehyperlinks	INTJ
ct-12609	304	7	false	false	ADJ
ct-12609	304	8	/includeinteractive	/includeinteractive	ADJ
ct-12609	304	9	false	false	ADJ
ct-12609	304	10	/includelayers	/includelayer	NOUN
ct-12609	304	11	false	false	ADJ
ct-12609	304	12	/includeprofiles	/includeprofiles	NOUN
ct-12609	304	13	true	true	ADJ
ct-12609	304	14	/marksoffset	/marksoffset	ADJ
ct-12609	304	15	6	6	NUM
ct-12609	304	16	/marksweight	/marksweight	NOUN
ct-12609	304	17	0.250000	0.250000	NUM
ct-12609	304	18	/multimediahandling	/multimediahandling	NOUN
ct-12609	304	19	/useobjectsettings	/useobjectsettings	PRON
ct-12609	304	20	/namespace	/namespace	PUNCT
ct-12609	305	1	[	[	PUNCT
ct-12609	305	2	(	(	PUNCT
ct-12609	305	3	adobe	adobe	PROPN
ct-12609	305	4	)	)	PUNCT
ct-12609	305	5	(	(	PUNCT
ct-12609	305	6	creativesuite	creativesuite	NOUN
ct-12609	305	7	)	)	PUNCT
ct-12609	305	8	(	(	PUNCT
ct-12609	305	9	2.0	2.0	NUM
ct-12609	305	10	)	)	PUNCT
ct-12609	305	11	]	]	PUNCT
ct-12609	306	1	/pdfxoutputintentprofileselector	/pdfxoutputintentprofileselector	NOUN
ct-12609	307	1	/na	/na	PUNCT
ct-12609	307	2	/pagemarksfile	/pagemarksfile	PUNCT
ct-12609	307	3	/romandefault	/romandefault	VERB
ct-12609	307	4	/preserveediting	/preserveedite	VERB
ct-12609	307	5	true	true	ADJ
ct-12609	307	6	/untaggedcmykhandling	/untaggedcmykhandling	NOUN
ct-12609	307	7	/leaveuntagged	/leaveuntagge	VERB
ct-12609	307	8	/untaggedrgbhandling	/untaggedrgbhandling	NOUN
ct-12609	307	9	/leaveuntagged	/leaveuntagged	ADJ
ct-12609	308	1	/usedocumentbleed	/usedocumentbleed	INTJ
ct-12609	308	2	false	false	INTJ
ct-12609	308	3	>	>	PUNCT
ct-12609	308	4	>	>	X
ct-12609	308	5	<	<	X
ct-12609	308	6	<	<	X
ct-12609	308	7	/allowimagebreaks	/allowimagebreaks	ADJ
ct-12609	308	8	true	true	ADJ
ct-12609	308	9	/allowtablebreaks	/allowtablebreak	NOUN
ct-12609	308	10	true	true	ADJ
ct-12609	308	11	/expandpage	/expandpage	ADJ
ct-12609	308	12	false	false	ADJ
ct-12609	308	13	/honorbaseurl	/honorbaseurl	ADJ
ct-12609	308	14	true	true	ADJ
ct-12609	308	15	/honorrollovereffect	/honorrollovereffect	ADJ
ct-12609	308	16	false	false	ADJ
ct-12609	308	17	/ignorehtmlpagebreaks	/ignorehtmlpagebreaks	INTJ
ct-12609	308	18	false	false	ADJ
ct-12609	308	19	/includeheaderfooter	/includeheaderfooter	NOUN
ct-12609	308	20	false	false	ADJ
ct-12609	308	21	/marginoffset	/marginoffset	PUNCT
ct-12609	309	1	[	[	PUNCT
ct-12609	309	2	0	0	NUM
ct-12609	309	3	0	0	NUM
ct-12609	309	4	0	0	NUM
ct-12609	309	5	0	0	NUM
ct-12609	309	6	]	]	PUNCT
ct-12609	309	7	/metadataauthor	/metadataauthor	SYM
ct-12609	309	8	(	(	PUNCT
ct-12609	309	9	)	)	PUNCT
ct-12609	309	10	/metadatakeywords	/metadatakeyword	NOUN
ct-12609	309	11	(	(	PUNCT
ct-12609	309	12	)	)	PUNCT
ct-12609	309	13	/metadatasubject	/metadatasubject	PUNCT
ct-12609	309	14	(	(	PUNCT
ct-12609	309	15	)	)	PUNCT
ct-12609	309	16	/metadatatitle	/metadatatitle	INTJ
ct-12609	309	17	(	(	PUNCT
ct-12609	309	18	)	)	PUNCT
ct-12609	309	19	/metricpagesize	/metricpagesize	PUNCT
ct-12609	309	20	[	[	PUNCT
ct-12609	309	21	0	0	NUM
ct-12609	309	22	0	0	NUM
ct-12609	309	23	]	]	PUNCT
ct-12609	309	24	/metricunit	/metricunit	PUNCT
ct-12609	309	25	/inch	/inch	PUNCT
ct-12609	310	1	/mobilecompatible	/mobilecompatible	ADJ
ct-12609	311	1	0	0	NUM
ct-12609	312	1	/namespace	/namespace	NOUN
ct-12609	313	1	[	[	PUNCT
ct-12609	313	2	(	(	PUNCT
ct-12609	313	3	adobe	adobe	PROPN
ct-12609	313	4	)	)	PUNCT
ct-12609	313	5	(	(	PUNCT
ct-12609	313	6	golive	golive	NOUN
ct-12609	313	7	)	)	PUNCT
ct-12609	313	8	(	(	PUNCT
ct-12609	313	9	8.0	8.0	NUM
ct-12609	313	10	)	)	PUNCT
ct-12609	313	11	]	]	PUNCT
ct-12609	313	12	/openzoomtohtmlfontsize	/openzoomtohtmlfontsize	PUNCT
ct-12609	313	13	false	false	ADJ
ct-12609	313	14	/pageorientation	/pageorientation	NOUN
ct-12609	313	15	/portrait	/portrait	NOUN
ct-12609	313	16	/removebackground	/removebackground	VERB
ct-12609	314	1	false	false	ADJ
ct-12609	314	2	/shrinkcontent	/shrinkcontent	NOUN
ct-12609	314	3	true	true	ADJ
ct-12609	314	4	/treatcolorsas	/treatcolorsa	NOUN
ct-12609	314	5	/mainmonitorcolors	/mainmonitorcolors	INTJ
ct-12609	315	1	/useembeddedprofiles	/useembeddedprofiles	PROPN
ct-12609	315	2	false	false	ADJ
ct-12609	315	3	/usehtmltitleasmetadata	/usehtmltitleasmetadata	ADJ
ct-12609	315	4	true	true	ADJ
ct-12609	315	5	>	>	PUNCT
ct-12609	315	6	>	>	X
ct-12609	315	7	]	]	PUNCT
ct-12609	315	8	>	>	PUNCT
ct-12609	315	9	>	>	X
ct-12609	315	10	setdistillerparams	setdistillerparam	NOUN
ct-12609	316	1	<	<	X
ct-12609	316	2	<	<	X
ct-12609	316	3	/hwresolution	/hwresolution	NOUN
ct-12609	317	1	[	[	X
ct-12609	317	2	2400	2400	NUM
ct-12609	317	3	2400	2400	NUM
ct-12609	317	4	]	]	PUNCT
ct-12609	317	5	/pagesize	/pagesize	X
ct-12609	318	1	[	[	X
ct-12609	318	2	612.000	612.000	NUM
ct-12609	318	3	792.000	792.000	NUM
ct-12609	318	4	]	]	PUNCT
ct-12609	318	5	>	>	PUNCT
ct-12609	318	6	>	>	X
ct-12609	318	7	setpagedevice	setpagedevice	PROPN
