id	sid	tid	token	lemma	pos
ct-9204	1	1	extracellular	extracellular	ADJ
ct-9204	1	2	vesicles	vesicle	NOUN
ct-9204	1	3	and	and	CCONJ
ct-9204	1	4	assisted	assist	VERB
ct-9204	1	5	reproductive	reproductive	ADJ
ct-9204	1	6	technology	technology	NOUN
ct-9204	1	7	extracellular	extracellular	ADJ
ct-9204	1	8	vesicles	vesicle	NOUN
ct-9204	1	9	and	and	CCONJ
ct-9204	1	10	assisted	assist	VERB
ct-9204	1	11	reproductive	reproductive	ADJ
ct-9204	1	12	technology	technology	NOUN
ct-9204	1	13	jennifer	jennifer	PROPN
ct-9204	1	14	nagashima	nagashima	PROPN
ct-9204	1	15	,	,	PUNCT
ct-9204	1	16	marcia	marcia	PROPN
ct-9204	1	17	ferraz	ferraz	PROPN
ct-9204	1	18	,	,	PUNCT
ct-9204	1	19	nucharin	nucharin	PROPN
ct-9204	1	20	songsasen	songsasen	PROPN
ct-9204	1	21	center	center	PROPN
ct-9204	1	22	for	for	ADP
ct-9204	1	23	species	species	NOUN
ct-9204	1	24	survival	survival	NOUN
ct-9204	1	25	,	,	PUNCT
ct-9204	1	26	smithsonian	smithsonian	PROPN
ct-9204	1	27	conservation	conservation	PROPN
ct-9204	1	28	biology	biology	NOUN
ct-9204	1	29	institute	institute	VERB
ct-9204	1	30	national	national	ADJ
ct-9204	1	31	zoological	zoological	ADJ
ct-9204	1	32	park	park	NOUN
ct-9204	1	33	,	,	PUNCT
ct-9204	1	34	front	front	ADJ
ct-9204	1	35	royal	royal	NOUN
ct-9204	1	36	,	,	PUNCT
ct-9204	1	37	va	va	NOUN
ct-9204	1	38	abstract	abstract	ADJ
ct-9204	1	39	research	research	NOUN
ct-9204	1	40	in	in	ADP
ct-9204	1	41	biogenesis	biogenesis	NOUN
ct-9204	1	42	,	,	PUNCT
ct-9204	1	43	composition	composition	NOUN
ct-9204	1	44	,	,	PUNCT
ct-9204	1	45	uptake	uptake	ADJ
ct-9204	1	46	,	,	PUNCT
ct-9204	1	47	and	and	CCONJ
ct-9204	1	48	functionality	functionality	NOUN
ct-9204	1	49	of	of	ADP
ct-9204	1	50	extracellular	extracellular	ADJ
ct-9204	1	51	vehicles	vehicle	NOUN
ct-9204	1	52	(	(	PUNCT
ct-9204	1	53	evs	evs	NOUN
ct-9204	1	54	)	)	PUNCT
ct-9204	1	55	has	have	AUX
ct-9204	1	56	dramatically	dramatically	ADV
ct-9204	1	57	expanded	expand	VERB
ct-9204	1	58	in	in	ADP
ct-9204	1	59	recent	recent	ADJ
ct-9204	1	60	decades	decade	NOUN
ct-9204	1	61	.	.	PUNCT
ct-9204	2	1	these	these	DET
ct-9204	2	2	lipid	lipid	ADJ
ct-9204	2	3	membrane	membrane	NOUN
ct-9204	2	4	bound	bind	VERB
ct-9204	2	5	particles	particle	NOUN
ct-9204	2	6	secreted	secrete	VERB
ct-9204	2	7	from	from	ADP
ct-9204	2	8	all	all	DET
ct-9204	2	9	cells	cell	NOUN
ct-9204	2	10	contain	contain	VERB
ct-9204	2	11	regulatory	regulatory	ADJ
ct-9204	2	12	molecules	molecule	NOUN
ct-9204	2	13	(	(	PUNCT
ct-9204	2	14	proteins	protein	NOUN
ct-9204	2	15	,	,	PUNCT
ct-9204	2	16	peptides	peptide	NOUN
ct-9204	2	17	,	,	PUNCT
ct-9204	2	18	rnas	rna	NOUN
ct-9204	2	19	,	,	PUNCT
ct-9204	2	20	dna	dna	NOUN
ct-9204	2	21	fragments	fragment	NOUN
ct-9204	2	22	,	,	PUNCT
ct-9204	2	23	and	and	CCONJ
ct-9204	2	24	lipids	lipid	VERB
ct-9204	2	25	)	)	PUNCT
ct-9204	2	26	that	that	PRON
ct-9204	2	27	are	be	AUX
ct-9204	2	28	transferred	transfer	VERB
ct-9204	2	29	to	to	PART
ct-9204	2	30	target	target	VERB
ct-9204	2	31	cells	cell	NOUN
ct-9204	2	32	upon	upon	SCONJ
ct-9204	2	33	binding	bind	VERB
ct-9204	2	34	to	to	ADP
ct-9204	2	35	the	the	DET
ct-9204	2	36	plasma	plasma	NOUN
ct-9204	2	37	membrane	membrane	NOUN
ct-9204	2	38	.	.	PUNCT
ct-9204	3	1	roles	role	NOUN
ct-9204	3	2	of	of	ADP
ct-9204	3	3	evs	evs	NOUN
ct-9204	3	4	were	be	AUX
ct-9204	3	5	studied	study	VERB
ct-9204	3	6	in	in	ADP
ct-9204	3	7	cell	cell	NOUN
ct-9204	3	8	to	to	ADP
ct-9204	3	9	cell	cell	NOUN
ct-9204	3	10	communication	communication	NOUN
ct-9204	3	11	,	,	PUNCT
ct-9204	3	12	mediation	mediation	NOUN
ct-9204	3	13	of	of	ADP
ct-9204	3	14	cancer	cancer	NOUN
ct-9204	3	15	development	development	NOUN
ct-9204	3	16	and	and	CCONJ
ct-9204	3	17	immune	immune	ADJ
ct-9204	3	18	response	response	NOUN
ct-9204	3	19	,	,	PUNCT
ct-9204	3	20	as	as	ADP
ct-9204	3	21	biomarkers	biomarker	NOUN
ct-9204	3	22	for	for	ADP
ct-9204	3	23	disease	disease	NOUN
ct-9204	3	24	and	and	CCONJ
ct-9204	3	25	potential	potential	ADJ
ct-9204	3	26	drug	drug	NOUN
ct-9204	3	27	delivery	delivery	NOUN
ct-9204	3	28	systems	system	NOUN
ct-9204	3	29	.	.	PUNCT
ct-9204	4	1	more	more	ADV
ct-9204	4	2	recently	recently	ADV
ct-9204	4	3	,	,	PUNCT
ct-9204	4	4	studies	study	NOUN
ct-9204	4	5	were	be	AUX
ct-9204	4	6	conducted	conduct	VERB
ct-9204	4	7	to	to	PART
ct-9204	4	8	investigate	investigate	VERB
ct-9204	4	9	roles	role	NOUN
ct-9204	4	10	of	of	ADP
ct-9204	4	11	evs	evs	NOUN
ct-9204	4	12	in	in	ADP
ct-9204	4	13	reproduction	reproduction	NOUN
ct-9204	4	14	,	,	PUNCT
ct-9204	4	15	ranging	range	VERB
ct-9204	4	16	from	from	ADP
ct-9204	4	17	gamete	gamete	ADJ
ct-9204	4	18	maturation	maturation	NOUN
ct-9204	4	19	,	,	PUNCT
ct-9204	4	20	fertilization	fertilization	NOUN
ct-9204	4	21	,	,	PUNCT
ct-9204	4	22	and	and	CCONJ
ct-9204	4	23	embryonic	embryonic	ADJ
ct-9204	4	24	development	development	NOUN
ct-9204	4	25	to	to	ADP
ct-9204	4	26	implantation	implantation	NOUN
ct-9204	4	27	.	.	PUNCT
ct-9204	5	1	as	as	SCONJ
ct-9204	5	2	such	such	ADJ
ct-9204	5	3	,	,	PUNCT
ct-9204	5	4	potential	potential	ADJ
ct-9204	5	5	use	use	NOUN
ct-9204	5	6	of	of	ADP
ct-9204	5	7	evs	evs	NOUN
ct-9204	5	8	for	for	ADP
ct-9204	5	9	assisted	assist	VERB
ct-9204	5	10	reproductive	reproductive	ADJ
ct-9204	5	11	technologies	technology	NOUN
ct-9204	5	12	(	(	PUNCT
ct-9204	5	13	art	art	NOUN
ct-9204	5	14	)	)	PUNCT
ct-9204	5	15	has	have	AUX
ct-9204	5	16	garnered	garner	VERB
ct-9204	5	17	substantial	substantial	ADJ
ct-9204	5	18	interest	interest	NOUN
ct-9204	5	19	.	.	PUNCT
ct-9204	6	1	objectives	objective	NOUN
ct-9204	6	2	of	of	ADP
ct-9204	6	3	this	this	DET
ct-9204	6	4	review	review	NOUN
ct-9204	6	5	are	be	AUX
ct-9204	6	6	to	to	PART
ct-9204	6	7	present	present	VERB
ct-9204	6	8	current	current	ADJ
ct-9204	6	9	understanding	understanding	NOUN
ct-9204	6	10	of	of	ADP
ct-9204	6	11	evs	evs	NOUN
ct-9204	6	12	in	in	ADP
ct-9204	6	13	reproduction	reproduction	NOUN
ct-9204	6	14	,	,	PUNCT
ct-9204	6	15	with	with	ADP
ct-9204	6	16	particular	particular	ADJ
ct-9204	6	17	regard	regard	NOUN
ct-9204	6	18	to	to	ADP
ct-9204	6	19	recent	recent	ADJ
ct-9204	6	20	research	research	NOUN
ct-9204	6	21	in	in	ADP
ct-9204	6	22	understanding	understand	VERB
ct-9204	6	23	influence	influence	NOUN
ct-9204	6	24	of	of	ADP
ct-9204	6	25	reproductive	reproductive	ADJ
ct-9204	6	26	cycles	cycle	NOUN
ct-9204	6	27	on	on	ADP
ct-9204	6	28	ev	ev	INTJ
ct-9204	6	29	production	production	NOUN
ct-9204	6	30	and	and	CCONJ
ct-9204	6	31	cargo	cargo	NOUN
ct-9204	6	32	composition	composition	NOUN
ct-9204	6	33	,	,	PUNCT
ct-9204	6	34	and	and	CCONJ
ct-9204	6	35	to	to	PART
ct-9204	6	36	discuss	discuss	VERB
ct-9204	6	37	therapeutic	therapeutic	ADJ
ct-9204	6	38	potential	potential	NOUN
ct-9204	6	39	of	of	ADP
ct-9204	6	40	evs	evs	NOUN
ct-9204	6	41	in	in	ADP
ct-9204	6	42	reproductive	reproductive	ADJ
ct-9204	6	43	technologies	technology	NOUN
ct-9204	6	44	,	,	PUNCT
ct-9204	6	45	including	include	VERB
ct-9204	6	46	cryopreservation	cryopreservation	NOUN
ct-9204	6	47	and	and	CCONJ
ct-9204	6	48	areas	area	NOUN
ct-9204	6	49	of	of	ADP
ct-9204	6	50	research	research	NOUN
ct-9204	6	51	that	that	PRON
ct-9204	6	52	remain	remain	VERB
ct-9204	6	53	to	to	PART
ct-9204	6	54	be	be	AUX
ct-9204	6	55	explored	explore	VERB
ct-9204	6	56	for	for	ADP
ct-9204	6	57	efficient	efficient	ADJ
ct-9204	6	58	application	application	NOUN
ct-9204	6	59	of	of	ADP
ct-9204	6	60	evs	evs	NOUN
ct-9204	6	61	in	in	ADP
ct-9204	6	62	art	art	NOUN
ct-9204	6	63	.	.	PUNCT
ct-9204	7	1	keywords	keyword	NOUN
ct-9204	7	2	:	:	PUNCT
ct-9204	7	3	extracellular	extracellular	ADJ
ct-9204	7	4	vesicles	vesicle	NOUN
ct-9204	7	5	,	,	PUNCT
ct-9204	7	6	gametes	gamete	NOUN
ct-9204	7	7	,	,	PUNCT
ct-9204	7	8	cryopreservation	cryopreservation	NOUN
ct-9204	7	9	,	,	PUNCT
ct-9204	7	10	organs	organ	NOUN
ct-9204	7	11	on	on	ADP
ct-9204	7	12	a	a	DET
ct-9204	7	13	chip	chip	NOUN
ct-9204	7	14	,	,	PUNCT
ct-9204	7	15	synthetic	synthetic	ADJ
ct-9204	7	16	vesicle	vesicle	NOUN
ct-9204	7	17	introduction	introduction	NOUN
ct-9204	7	18	extracellular	extracellular	ADJ
ct-9204	7	19	vehicles	vehicle	NOUN
ct-9204	7	20	(	(	PUNCT
ct-9204	7	21	evs	evs	NOUN
ct-9204	7	22	)	)	PUNCT
ct-9204	7	23	are	be	AUX
ct-9204	7	24	lipid	lipid	ADJ
ct-9204	7	25	membrane	membrane	NOUN
ct-9204	7	26	bound	bind	VERB
ct-9204	7	27	vesicles	vesicle	NOUN
ct-9204	7	28	secreted	secrete	VERB
ct-9204	7	29	by	by	ADP
ct-9204	7	30	all	all	DET
ct-9204	7	31	cells.1	cells.1	PROPN
ct-9204	7	32	evs	evs	NOUN
ct-9204	7	33	include	include	VERB
ct-9204	7	34	exosomes	exosome	NOUN
ct-9204	7	35	(	(	PUNCT
ct-9204	7	36	30	30	NUM
ct-9204	7	37	100	100	NUM
ct-9204	7	38	nm	nm	NOUN
ct-9204	7	39	in	in	ADP
ct-9204	7	40	size	size	NOUN
ct-9204	7	41	)	)	PUNCT
ct-9204	7	42	,	,	PUNCT
ct-9204	7	43	released	release	VERB
ct-9204	7	44	via	via	ADP
ct-9204	7	45	fusion	fusion	NOUN
ct-9204	7	46	of	of	ADP
ct-9204	7	47	a	a	DET
ct-9204	7	48	multivesicle	multivesicle	NOUN
ct-9204	7	49	body	body	NOUN
ct-9204	7	50	with	with	ADP
ct-9204	7	51	a	a	DET
ct-9204	7	52	cell	cell	NOUN
ct-9204	7	53	’s	’s	PART
ct-9204	7	54	plasma	plasma	NOUN
ct-9204	7	55	membrane	membrane	NOUN
ct-9204	7	56	;	;	PUNCT
ct-9204	7	57	microvesicles	microvesicle	NOUN
ct-9204	7	58	(	(	PUNCT
ct-9204	7	59	mv	mv	PROPN
ct-9204	7	60	,	,	PUNCT
ct-9204	7	61	also	also	ADV
ct-9204	7	62	known	know	VERB
ct-9204	7	63	as	as	ADP
ct-9204	7	64	ectosomes	ectosome	NOUN
ct-9204	7	65	,	,	PUNCT
ct-9204	7	66	100	100	NUM
ct-9204	7	67	1000	1000	NUM
ct-9204	7	68	nm	nm	NOUN
ct-9204	7	69	)	)	PUNCT
ct-9204	7	70	,	,	PUNCT
ct-9204	7	71	shed	shed	VERB
ct-9204	7	72	via	via	ADP
ct-9204	7	73	budding	bud	VERB
ct-9204	7	74	from	from	ADP
ct-9204	7	75	plasma	plasma	NOUN
ct-9204	7	76	membrane;2	membrane;2	NOUN
ct-9204	7	77	and	and	CCONJ
ct-9204	7	78	apoptotic	apoptotic	ADJ
ct-9204	7	79	bodies	body	NOUN
ct-9204	7	80	(	(	PUNCT
ct-9204	7	81	up	up	ADP
ct-9204	7	82	to	to	PART
ct-9204	7	83	5000	5000	NUM
ct-9204	7	84	nm	nm	NOUN
ct-9204	7	85	)	)	PUNCT
ct-9204	7	86	,	,	PUNCT
ct-9204	7	87	formed	form	VERB
ct-9204	7	88	through	through	ADP
ct-9204	7	89	contraction	contraction	NOUN
ct-9204	7	90	and	and	CCONJ
ct-9204	7	91	membrane	membrane	NOUN
ct-9204	7	92	blebbing	blebbing	NOUN
ct-9204	7	93	of	of	ADP
ct-9204	7	94	dying	die	VERB
ct-9204	7	95	cells3	cells3	NOUN
ct-9204	7	96	(	(	PUNCT
ct-9204	7	97	figure	figure	NOUN
ct-9204	7	98	1	1	NUM
ct-9204	7	99	)	)	PUNCT
ct-9204	7	100	.	.	PUNCT
ct-9204	8	1	evs	evs	AUX
ct-9204	8	2	contain	contain	VERB
ct-9204	8	3	regulatory	regulatory	ADJ
ct-9204	8	4	molecules	molecule	NOUN
ct-9204	8	5	,	,	PUNCT
ct-9204	8	6	including	include	VERB
ct-9204	8	7	proteins	protein	NOUN
ct-9204	8	8	,	,	PUNCT
ct-9204	8	9	peptides	peptide	NOUN
ct-9204	8	10	,	,	PUNCT
ct-9204	8	11	rna	rna	NOUN
ct-9204	8	12	species	specie	NOUN
ct-9204	8	13	,	,	PUNCT
ct-9204	8	14	lipids	lipid	NOUN
ct-9204	8	15	,	,	PUNCT
ct-9204	8	16	and	and	CCONJ
ct-9204	8	17	dna	dna	PROPN
ct-9204	8	18	fragments	fragment	NOUN
ct-9204	8	19	which	which	PRON
ct-9204	8	20	may	may	AUX
ct-9204	8	21	be	be	AUX
ct-9204	8	22	taken	take	VERB
ct-9204	8	23	up	up	ADP
ct-9204	8	24	by	by	ADP
ct-9204	8	25	nearby	nearby	ADJ
ct-9204	8	26	cells	cell	NOUN
ct-9204	8	27	via	via	ADP
ct-9204	8	28	either	either	CCONJ
ct-9204	8	29	fusion	fusion	NOUN
ct-9204	8	30	or	or	CCONJ
ct-9204	8	31	endocytosis	endocytosis	NOUN
ct-9204	8	32	of	of	ADP
ct-9204	8	33	vesicles	vesicle	NOUN
ct-9204	8	34	,	,	PUNCT
ct-9204	8	35	contributing	contribute	VERB
ct-9204	8	36	to	to	ADP
ct-9204	8	37	cell	cell	NOUN
ct-9204	8	38	to	to	ADP
ct-9204	8	39	cell	cell	NOUN
ct-9204	8	40	communication.4	communication.4	NOUN
ct-9204	8	41	owing	owe	VERB
ct-9204	8	42	to	to	ADP
ct-9204	8	43	size	size	NOUN
ct-9204	8	44	overlap	overlap	NOUN
ct-9204	8	45	between	between	ADP
ct-9204	8	46	exosomes	exosome	NOUN
ct-9204	8	47	and	and	CCONJ
ct-9204	8	48	mv	mv	NOUN
ct-9204	8	49	,	,	PUNCT
ct-9204	8	50	it	it	PRON
ct-9204	8	51	is	be	AUX
ct-9204	8	52	difficult	difficult	ADJ
ct-9204	8	53	to	to	PART
ct-9204	8	54	separate	separate	VERB
ct-9204	8	55	1	1	NUM
ct-9204	8	56	population	population	NOUN
ct-9204	8	57	from	from	ADP
ct-9204	8	58	another	another	PRON
ct-9204	8	59	and	and	CCONJ
ct-9204	8	60	the	the	DET
ct-9204	8	61	2	2	NUM
ct-9204	8	62	groups	group	NOUN
ct-9204	8	63	are	be	AUX
ct-9204	8	64	often	often	ADV
ct-9204	8	65	studied	study	VERB
ct-9204	8	66	together	together	ADV
ct-9204	8	67	as	as	ADP
ct-9204	8	68	extracellular	extracellular	ADJ
ct-9204	8	69	vesicles	vesicle	NOUN
ct-9204	8	70	,	,	PUNCT
ct-9204	8	71	or	or	CCONJ
ct-9204	8	72	“	"	PUNCT
ct-9204	8	73	evs	evs	VERB
ct-9204	8	74	”	"	PUNCT
ct-9204	8	75	in	in	ADP
ct-9204	8	76	healthy	healthy	ADJ
ct-9204	8	77	cells	cell	NOUN
ct-9204	8	78	(	(	PUNCT
ct-9204	8	79	i.e.	i.e.	X
ct-9204	8	80	excluding	exclude	VERB
ct-9204	8	81	apoptotic	apoptotic	ADJ
ct-9204	8	82	bodies	body	NOUN
ct-9204	8	83	)	)	PUNCT
ct-9204	8	84	.	.	PUNCT
ct-9204	9	1	multiple	multiple	ADJ
ct-9204	9	2	methods	method	NOUN
ct-9204	9	3	have	have	AUX
ct-9204	9	4	been	be	AUX
ct-9204	9	5	evaluated	evaluate	VERB
ct-9204	9	6	for	for	ADP
ct-9204	9	7	ev	ev	NOUN
ct-9204	9	8	isolation	isolation	NOUN
ct-9204	9	9	(	(	PUNCT
ct-9204	9	10	reviewed5	reviewed5	ADJ
ct-9204	9	11	)	)	PUNCT
ct-9204	9	12	,	,	PUNCT
ct-9204	9	13	including	include	VERB
ct-9204	9	14	ultracentrifugation	ultracentrifugation	NOUN
ct-9204	9	15	(	(	PUNCT
ct-9204	9	16	most	most	ADV
ct-9204	9	17	commonly	commonly	ADV
ct-9204	9	18	utilized	utilize	VERB
ct-9204	9	19	method6	method6	PROPN
ct-9204	9	20	)	)	PUNCT
ct-9204	9	21	,	,	PUNCT
ct-9204	9	22	density	density	NOUN
ct-9204	9	23	gradient	gradient	NOUN
ct-9204	9	24	centrifugation,7	centrifugation,7	NOUN
ct-9204	9	25	size	size	NOUN
ct-9204	9	26	-	-	PUNCT
ct-9204	9	27	exclusion	exclusion	NOUN
ct-9204	9	28	chromatography,8	chromatography,8	NOUN
ct-9204	9	29	ultrafiltration,9	ultrafiltration,9	NOUN
ct-9204	9	30	and	and	CCONJ
ct-9204	9	31	sequential	sequential	ADJ
ct-9204	9	32	filtration.10	filtration.10	ADJ
ct-9204	9	33	differences	difference	NOUN
ct-9204	9	34	in	in	ADP
ct-9204	9	35	isolation	isolation	NOUN
ct-9204	9	36	method	method	NOUN
ct-9204	9	37	become	become	VERB
ct-9204	9	38	significant	significant	ADJ
ct-9204	9	39	in	in	ADP
ct-9204	9	40	that	that	DET
ct-9204	9	41	subpopulations	subpopulation	NOUN
ct-9204	9	42	of	of	ADP
ct-9204	9	43	evs	evs	NOUN
ct-9204	9	44	(	(	PUNCT
ct-9204	9	45	i.e.	i.e.	X
ct-9204	9	46	more	more	ADJ
ct-9204	9	47	exosomes	exosome	NOUN
ct-9204	9	48	versus	versus	ADP
ct-9204	9	49	mv	mv	PROPN
ct-9204	9	50	,	,	PUNCT
ct-9204	9	51	or	or	CCONJ
ct-9204	9	52	ev	ev	INTJ
ct-9204	9	53	with	with	ADP
ct-9204	9	54	specific	specific	ADJ
ct-9204	9	55	surface	surface	NOUN
ct-9204	9	56	markers	marker	NOUN
ct-9204	9	57	)	)	PUNCT
ct-9204	9	58	may	may	AUX
ct-9204	9	59	be	be	AUX
ct-9204	9	60	preferentially	preferentially	ADV
ct-9204	9	61	purified	purify	VERB
ct-9204	9	62	,	,	PUNCT
ct-9204	9	63	based	base	VERB
ct-9204	9	64	on	on	ADP
ct-9204	9	65	isolation	isolation	NOUN
ct-9204	9	66	technique	technique	NOUN
ct-9204	9	67	.	.	PUNCT
ct-9204	10	1	for	for	ADP
ct-9204	10	2	example	example	NOUN
ct-9204	10	3	,	,	PUNCT
ct-9204	10	4	biological	biological	ADJ
ct-9204	10	5	activity	activity	NOUN
ct-9204	10	6	of	of	ADP
ct-9204	10	7	endometrial	endometrial	ADJ
ct-9204	10	8	evs	evs	NOUN
ct-9204	10	9	isolated	isolate	VERB
ct-9204	10	10	via	via	ADP
ct-9204	10	11	a	a	DET
ct-9204	10	12	commercially	commercially	ADV
ct-9204	10	13	available	available	ADJ
ct-9204	10	14	system	system	NOUN
ct-9204	10	15	were	be	AUX
ct-9204	10	16	compared	compare	VERB
ct-9204	10	17	with	with	ADP
ct-9204	10	18	those	those	PRON
ct-9204	10	19	purified	purify	VERB
ct-9204	10	20	via	via	ADP
ct-9204	10	21	ultracentrifugation	ultracentrifugation	NOUN
ct-9204	10	22	and	and	CCONJ
ct-9204	10	23	ultrafiltration.11	ultrafiltration.11	PROPN
ct-9204	10	24	although	although	SCONJ
ct-9204	10	25	ultracentrifugation	ultracentrifugation	NOUN
ct-9204	10	26	had	have	VERB
ct-9204	10	27	highest	high	ADJ
ct-9204	10	28	ev	ev	ADP
ct-9204	10	29	yield	yield	NOUN
ct-9204	10	30	,	,	PUNCT
ct-9204	10	31	evs	evs	NOUN
ct-9204	10	32	isolated	isolate	VERB
ct-9204	10	33	via	via	ADP
ct-9204	10	34	total	total	ADJ
ct-9204	10	35	exosome	exosome	PROPN
ct-9204	10	36	isolation	isolation	NOUN
ct-9204	10	37	kit	kit	NOUN
ct-9204	10	38	were	be	AUX
ct-9204	10	39	more	more	ADV
ct-9204	10	40	readily	readily	ADV
ct-9204	10	41	taken	take	VERB
ct-9204	10	42	up	up	ADP
ct-9204	10	43	by	by	ADP
ct-9204	10	44	trophoblast	trophoblast	ADJ
ct-9204	10	45	cells	cell	NOUN
ct-9204	10	46	,	,	PUNCT
ct-9204	10	47	indicating	indicate	VERB
ct-9204	10	48	better	well	ADJ
ct-9204	10	49	preservation	preservation	NOUN
ct-9204	10	50	of	of	ADP
ct-9204	10	51	biological	biological	ADJ
ct-9204	10	52	activity	activity	NOUN
ct-9204	10	53	.	.	PUNCT
ct-9204	11	1	further	far	ADV
ct-9204	11	2	,	,	PUNCT
ct-9204	11	3	regardless	regardless	ADV
ct-9204	11	4	of	of	ADP
ct-9204	11	5	purification	purification	NOUN
ct-9204	11	6	method	method	NOUN
ct-9204	11	7	,	,	PUNCT
ct-9204	11	8	copurified	copurifie	VERB
ct-9204	11	9	protein	protein	NOUN
ct-9204	11	10	aggregates	aggregate	NOUN
ct-9204	11	11	can	can	AUX
ct-9204	11	12	confound	confound	VERB
ct-9204	11	13	the	the	DET
ct-9204	11	14	results	result	NOUN
ct-9204	11	15	of	of	ADP
ct-9204	11	16	2	2	NUM
ct-9204	11	17	most	most	ADV
ct-9204	11	18	commonly	commonly	ADV
ct-9204	11	19	utilized	utilize	VERB
ct-9204	11	20	ev	ev	ADP
ct-9204	11	21	quantification	quantification	NOUN
ct-9204	11	22	methods	method	NOUN
ct-9204	11	23	,	,	PUNCT
ct-9204	11	24	namely	namely	ADV
ct-9204	11	25	,	,	PUNCT
ct-9204	11	26	colorimetric	colorimetric	ADJ
ct-9204	11	27	protein	protein	NOUN
ct-9204	11	28	assays	assay	NOUN
ct-9204	11	29	(	(	PUNCT
ct-9204	11	30	e.g.	e.g.	ADV
ct-9204	11	31	bca	bca	PROPN
ct-9204	11	32	)	)	PUNCT
ct-9204	11	33	and	and	CCONJ
ct-9204	11	34	nanoparticle	nanoparticle	NOUN
ct-9204	11	35	tracking	track	VERB
ct-9204	11	36	analysis	analysis	NOUN
ct-9204	11	37	(	(	PUNCT
ct-9204	11	38	nta).12	nta).12	X
ct-9204	11	39	additionally	additionally	ADV
ct-9204	11	40	,	,	PUNCT
ct-9204	11	41	our	our	PRON
ct-9204	11	42	ability	ability	NOUN
ct-9204	11	43	to	to	PART
ct-9204	11	44	fully	fully	ADV
ct-9204	11	45	characterize	characterize	VERB
ct-9204	11	46	evs	evs	NOUN
ct-9204	11	47	(	(	PUNCT
ct-9204	11	48	both	both	CCONJ
ct-9204	11	49	in	in	ADP
ct-9204	11	50	terms	term	NOUN
ct-9204	11	51	of	of	ADP
ct-9204	11	52	their	their	PRON
ct-9204	11	53	composition	composition	NOUN
ct-9204	11	54	and	and	CCONJ
ct-9204	11	55	functionality	functionality	NOUN
ct-9204	11	56	)	)	PUNCT
ct-9204	11	57	is	be	AUX
ct-9204	11	58	challenged	challenge	VERB
ct-9204	11	59	by	by	ADP
ct-9204	11	60	the	the	DET
ct-9204	11	61	heterogenous	heterogenous	ADJ
ct-9204	11	62	nature	nature	NOUN
ct-9204	11	63	of	of	ADP
ct-9204	11	64	isolated	isolated	ADJ
ct-9204	11	65	evs	evs	NOUN
ct-9204	11	66	.	.	PUNCT
ct-9204	12	1	nevertheless	nevertheless	ADV
ct-9204	12	2	,	,	PUNCT
ct-9204	12	3	some	some	DET
ct-9204	12	4	characteristic	characteristic	ADJ
ct-9204	12	5	features	feature	NOUN
ct-9204	12	6	of	of	ADP
ct-9204	12	7	ev	ev	DET
ct-9204	12	8	subpopulations	subpopulation	NOUN
ct-9204	12	9	have	have	AUX
ct-9204	12	10	been	be	AUX
ct-9204	12	11	described	describe	VERB
ct-9204	12	12	.	.	PUNCT
ct-9204	13	1	for	for	ADP
ct-9204	13	2	example	example	NOUN
ct-9204	13	3	,	,	PUNCT
ct-9204	13	4	owing	owe	VERB
ct-9204	13	5	to	to	ADP
ct-9204	13	6	differing	differ	VERB
ct-9204	13	7	methods	method	NOUN
ct-9204	13	8	of	of	ADP
ct-9204	13	9	release	release	NOUN
ct-9204	13	10	,	,	PUNCT
ct-9204	13	11	proteins	protein	NOUN
ct-9204	13	12	related	relate	VERB
ct-9204	13	13	to	to	ADP
ct-9204	13	14	endosomal	endosomal	ADJ
ct-9204	13	15	sorting	sorting	NOUN
ct-9204	13	16	complexes	complex	NOUN
ct-9204	13	17	required	require	VERB
ct-9204	13	18	for	for	ADP
ct-9204	13	19	transport	transport	NOUN
ct-9204	13	20	pathway	pathway	NOUN
ct-9204	13	21	are	be	AUX
ct-9204	13	22	common	common	ADJ
ct-9204	13	23	to	to	PART
ct-9204	13	24	exosomes.13	exosomes.13	VERB
ct-9204	13	25	exosomes	exosome	NOUN
ct-9204	13	26	are	be	AUX
ct-9204	13	27	also	also	ADV
ct-9204	13	28	enriched	enrich	VERB
ct-9204	13	29	in	in	ADP
ct-9204	13	30	tetraspanins	tetraspanin	NOUN
ct-9204	13	31	(	(	PUNCT
ct-9204	13	32	involved	involve	VERB
ct-9204	13	33	in	in	ADP
ct-9204	13	34	cell	cell	NOUN
ct-9204	13	35	adhesion	adhesion	NOUN
ct-9204	13	36	and	and	CCONJ
ct-9204	13	37	signaling14	signaling14	NOUN
ct-9204	13	38	)	)	PUNCT
ct-9204	13	39	and	and	CCONJ
ct-9204	13	40	heat	heat	NOUN
ct-9204	13	41	shock	shock	NOUN
ct-9204	13	42	proteins.15,16	proteins.15,16	NOUN
ct-9204	13	43	mv	mv	PROPN
ct-9204	13	44	contain	contain	VERB
ct-9204	13	45	higher	high	ADJ
ct-9204	13	46	concentrations	concentration	NOUN
ct-9204	13	47	of	of	ADP
ct-9204	13	48	proteins	protein	NOUN
ct-9204	13	49	associated	associate	VERB
ct-9204	13	50	with	with	ADP
ct-9204	13	51	plasma	plasma	NOUN
ct-9204	13	52	membrane.1	membrane.1	PROPN
ct-9204	13	53	although	although	SCONJ
ct-9204	13	54	lipid	lipid	ADJ
ct-9204	13	55	characterization	characterization	NOUN
ct-9204	13	56	has	have	AUX
ct-9204	13	57	been	be	AUX
ct-9204	13	58	particularly	particularly	ADV
ct-9204	13	59	understudied	understudied	ADJ
ct-9204	13	60	in	in	ADP
ct-9204	13	61	evs	evs	NOUN
ct-9204	13	62	field	field	NOUN
ct-9204	13	63	as	as	ADP
ct-9204	13	64	a	a	DET
ct-9204	13	65	whole,17	whole,17	ADJ
ct-9204	13	66	lipid	lipid	NOUN
ct-9204	13	67	clinical	clinical	ADJ
ct-9204	13	68	theriogenology	theriogenology	NOUN
ct-9204	14	1	•	•	NOUN
ct-9204	14	2	volume	volume	NOUN
ct-9204	14	3	12	12	NUM
ct-9204	14	4	number	number	NOUN
ct-9204	14	5	2	2	NUM
ct-9204	14	6	•	•	NOUN
ct-9204	14	7	june	june	PROPN
ct-9204	14	8	2020	2020	NUM
ct-9204	14	9	89	89	NUM
ct-9204	14	10	composition	composition	NOUN
ct-9204	14	11	and	and	CCONJ
ct-9204	14	12	high	high	ADJ
ct-9204	14	13	cholesterol	cholesterol	NOUN
ct-9204	14	14	/	/	SYM
ct-9204	14	15	phospholipid	phospholipid	NOUN
ct-9204	14	16	ratio	ratio	NOUN
ct-9204	14	17	of	of	ADP
ct-9204	14	18	evs	evs	NOUN
ct-9204	14	19	results	result	NOUN
ct-9204	14	20	in	in	ADP
ct-9204	14	21	notable	notable	ADJ
ct-9204	14	22	membrane	membrane	NOUN
ct-9204	14	23	stability	stability	NOUN
ct-9204	14	24	,	,	PUNCT
ct-9204	14	25	which	which	PRON
ct-9204	14	26	presumably	presumably	ADV
ct-9204	14	27	allows	allow	VERB
ct-9204	14	28	for	for	ADP
ct-9204	14	29	greater	great	ADJ
ct-9204	14	30	protection	protection	NOUN
ct-9204	14	31	of	of	ADP
ct-9204	14	32	cargo	cargo	NOUN
ct-9204	14	33	and	and	CCONJ
ct-9204	14	34	evs	evs	VERB
ct-9204	14	35	in	in	ADP
ct-9204	14	36	vitro	vitro	X
ct-9204	14	37	longevity.18	longevity.18	VERB
ct-9204	14	38	in	in	ADP
ct-9204	14	39	response	response	NOUN
ct-9204	14	40	to	to	ADP
ct-9204	14	41	confusion	confusion	NOUN
ct-9204	14	42	associated	associate	VERB
ct-9204	14	43	with	with	ADP
ct-9204	14	44	the	the	DET
ct-9204	14	45	heterogeneity	heterogeneity	NOUN
ct-9204	14	46	of	of	ADP
ct-9204	14	47	evs	evs	NOUN
ct-9204	14	48	and	and	CCONJ
ct-9204	14	49	diversity	diversity	NOUN
ct-9204	14	50	of	of	ADP
ct-9204	14	51	purification	purification	NOUN
ct-9204	14	52	and	and	CCONJ
ct-9204	14	53	quantification	quantification	NOUN
ct-9204	14	54	methods	method	NOUN
ct-9204	14	55	,	,	PUNCT
ct-9204	14	56	in	in	ADP
ct-9204	14	57	2018	2018	NUM
ct-9204	14	58	,	,	PUNCT
ct-9204	14	59	the	the	DET
ct-9204	14	60	international	international	ADJ
ct-9204	14	61	society	society	NOUN
ct-9204	14	62	for	for	ADP
ct-9204	14	63	extracellular	extracellular	ADJ
ct-9204	14	64	vesicles	vesicle	NOUN
ct-9204	14	65	published	publish	VERB
ct-9204	14	66	updated	update	VERB
ct-9204	14	67	standards	standard	NOUN
ct-9204	14	68	for	for	ADP
ct-9204	14	69	minimal	minimal	ADJ
ct-9204	14	70	information	information	NOUN
ct-9204	14	71	for	for	ADP
ct-9204	14	72	ev	ev	PROPN
ct-9204	14	73	studies.19	studies.19	NOUN
ct-9204	14	74	these	these	PRON
ct-9204	14	75	serve	serve	VERB
ct-9204	14	76	as	as	ADP
ct-9204	14	77	a	a	DET
ct-9204	14	78	guide	guide	NOUN
ct-9204	14	79	for	for	ADP
ct-9204	14	80	ev	ev	NOUN
ct-9204	14	81	isolation	isolation	NOUN
ct-9204	14	82	,	,	PUNCT
ct-9204	14	83	classification	classification	NOUN
ct-9204	14	84	,	,	PUNCT
ct-9204	14	85	and	and	CCONJ
ct-9204	14	86	nomenclature	nomenclature	NOUN
ct-9204	14	87	,	,	PUNCT
ct-9204	14	88	and	and	CCONJ
ct-9204	14	89	are	be	AUX
ct-9204	14	90	important	important	ADJ
ct-9204	14	91	to	to	PART
ct-9204	14	92	reduce	reduce	VERB
ct-9204	14	93	variability	variability	NOUN
ct-9204	14	94	in	in	ADP
ct-9204	14	95	research	research	NOUN
ct-9204	14	96	results	result	NOUN
ct-9204	14	97	among	among	ADP
ct-9204	14	98	laboratories	laboratory	NOUN
ct-9204	14	99	which	which	PRON
ct-9204	14	100	are	be	AUX
ct-9204	14	101	due	due	ADJ
ct-9204	14	102	to	to	ADP
ct-9204	14	103	inconsistent	inconsistent	ADJ
ct-9204	14	104	appellations	appellation	NOUN
ct-9204	14	105	,	,	PUNCT
ct-9204	14	106	or	or	CCONJ
ct-9204	14	107	attribution	attribution	NOUN
ct-9204	14	108	of	of	ADP
ct-9204	14	109	functions	function	NOUN
ct-9204	14	110	specifically	specifically	ADV
ct-9204	14	111	to	to	ADP
ct-9204	14	112	mv	mv	NOUN
ct-9204	14	113	/	/	SYM
ct-9204	14	114	exosomes	exosome	NOUN
ct-9204	14	115	when	when	SCONJ
ct-9204	14	116	isolation	isolation	NOUN
ct-9204	14	117	protocols	protocol	NOUN
ct-9204	14	118	produce	produce	VERB
ct-9204	14	119	heterogenous	heterogenous	ADJ
ct-9204	14	120	populations	population	NOUN
ct-9204	14	121	.	.	PUNCT
ct-9204	15	1	improved	improve	VERB
ct-9204	15	2	understanding	understanding	NOUN
ct-9204	15	3	of	of	ADP
ct-9204	15	4	ev	ev	ADP
ct-9204	15	5	sub	sub	ADJ
ct-9204	15	6	-	-	ADJ
ct-9204	15	7	population	population	ADJ
ct-9204	15	8	compositions	composition	NOUN
ct-9204	15	9	are	be	AUX
ct-9204	15	10	also	also	ADV
ct-9204	15	11	poised	poise	VERB
ct-9204	15	12	to	to	PART
ct-9204	15	13	hasten	hasten	VERB
ct-9204	15	14	elucidation	elucidation	NOUN
ct-9204	15	15	of	of	ADP
ct-9204	15	16	the	the	DET
ct-9204	15	17	mechanisms	mechanism	NOUN
ct-9204	15	18	of	of	ADP
ct-9204	15	19	ev	ev	INTJ
ct-9204	15	20	uptake	uptake	NOUN
ct-9204	15	21	into	into	ADP
ct-9204	15	22	‘	'	PUNCT
ct-9204	15	23	recipient	recipient	NOUN
ct-9204	15	24	’	'	PUNCT
ct-9204	15	25	cells	cell	NOUN
ct-9204	15	26	.	.	PUNCT
ct-9204	16	1	it	it	PRON
ct-9204	16	2	is	be	AUX
ct-9204	16	3	currently	currently	ADV
ct-9204	16	4	understood	understand	VERB
ct-9204	16	5	that	that	SCONJ
ct-9204	16	6	evs	evs	NOUN
ct-9204	16	7	are	be	AUX
ct-9204	16	8	taken	take	VERB
ct-9204	16	9	up	up	ADP
ct-9204	16	10	by	by	ADP
ct-9204	16	11	cells	cell	NOUN
ct-9204	16	12	through	through	ADP
ct-9204	16	13	a	a	DET
ct-9204	16	14	variety	variety	NOUN
ct-9204	16	15	of	of	ADP
ct-9204	16	16	pathways	pathway	NOUN
ct-9204	16	17	,	,	PUNCT
ct-9204	16	18	including	include	VERB
ct-9204	16	19	clathrin	clathrin	NOUN
ct-9204	16	20	-	-	PUNCT
ct-9204	16	21	mediated	mediate	VERB
ct-9204	16	22	endocytosis	endocytosis	NOUN
ct-9204	16	23	,	,	PUNCT
ct-9204	16	24	caveolin	caveolin	NOUN
ct-9204	16	25	-	-	PUNCT
ct-9204	16	26	mediated	mediate	VERB
ct-9204	16	27	uptake	uptake	NOUN
ct-9204	16	28	,	,	PUNCT
ct-9204	16	29	and	and	CCONJ
ct-9204	16	30	lipid	lipid	NOUN
ct-9204	16	31	raft	raft	NOUN
ct-9204	16	32	-	-	PUNCT
ct-9204	16	33	mediated	mediate	VERB
ct-9204	16	34	internalization	internalization	NOUN
ct-9204	16	35	(	(	PUNCT
ct-9204	16	36	reviewed20	reviewed20	NOUN
ct-9204	16	37	)	)	PUNCT
ct-9204	16	38	.	.	PUNCT
ct-9204	17	1	whereas	whereas	SCONJ
ct-9204	17	2	ev	ev	ADP
ct-9204	17	3	cargo	cargo	NOUN
ct-9204	17	4	transfer	transfer	NOUN
ct-9204	17	5	to	to	ADP
ct-9204	17	6	recipient	recipient	NOUN
ct-9204	17	7	cells	cell	NOUN
ct-9204	17	8	is	be	AUX
ct-9204	17	9	documented,21	documented,21	VERB
ct-9204	17	10	understanding	understand	VERB
ct-9204	17	11	molecular	molecular	ADJ
ct-9204	17	12	mechanisms	mechanism	NOUN
ct-9204	17	13	of	of	ADP
ct-9204	17	14	delivery	delivery	NOUN
ct-9204	17	15	is	be	AUX
ct-9204	17	16	an	an	DET
ct-9204	17	17	area	area	NOUN
ct-9204	17	18	necessitating	necessitate	VERB
ct-9204	17	19	further	further	ADJ
ct-9204	17	20	study	study	NOUN
ct-9204	17	21	.	.	PUNCT
ct-9204	18	1	still	still	ADV
ct-9204	18	2	,	,	PUNCT
ct-9204	18	3	evs	evs	NOUN
ct-9204	18	4	are	be	AUX
ct-9204	18	5	well	well	ADV
ct-9204	18	6	studied	study	VERB
ct-9204	18	7	for	for	ADP
ct-9204	18	8	their	their	PRON
ct-9204	18	9	role	role	NOUN
ct-9204	18	10	in	in	ADP
ct-9204	18	11	cell	cell	NOUN
ct-9204	18	12	to	to	ADP
ct-9204	18	13	cell	cell	NOUN
ct-9204	18	14	communication	communication	NOUN
ct-9204	18	15	,	,	PUNCT
ct-9204	18	16	including	include	VERB
ct-9204	18	17	in	in	ADP
ct-9204	18	18	mediating	mediate	VERB
ct-9204	18	19	cancer	cancer	NOUN
ct-9204	18	20	development	development	NOUN
ct-9204	18	21	(	(	PUNCT
ct-9204	18	22	reviewed5	reviewed5	ADJ
ct-9204	18	23	)	)	PUNCT
ct-9204	18	24	and	and	CCONJ
ct-9204	18	25	immune	immune	ADJ
ct-9204	18	26	response	response	NOUN
ct-9204	18	27	(	(	PUNCT
ct-9204	18	28	reviewed22	reviewed22	NOUN
ct-9204	18	29	)	)	PUNCT
ct-9204	18	30	.	.	PUNCT
ct-9204	19	1	release	release	NOUN
ct-9204	19	2	of	of	ADP
ct-9204	19	3	evs	evs	NOUN
ct-9204	19	4	by	by	ADP
ct-9204	19	5	cancer	cancer	NOUN
ct-9204	19	6	cells	cell	NOUN
ct-9204	19	7	and	and	CCONJ
ct-9204	19	8	immune	immune	ADJ
ct-9204	19	9	system	system	NOUN
ct-9204	19	10	stimulated	stimulate	VERB
ct-9204	19	11	interest	interest	NOUN
ct-9204	19	12	in	in	ADP
ct-9204	19	13	them	they	PRON
ct-9204	19	14	as	as	ADP
ct-9204	19	15	a	a	DET
ct-9204	19	16	source	source	NOUN
ct-9204	19	17	of	of	ADP
ct-9204	19	18	biomarkers	biomarker	NOUN
ct-9204	19	19	for	for	ADP
ct-9204	19	20	early	early	ADJ
ct-9204	19	21	disease	disease	NOUN
ct-9204	19	22	detection	detection	NOUN
ct-9204	19	23	(	(	PUNCT
ct-9204	19	24	reviewed23	reviewed23	NOUN
ct-9204	19	25	)	)	PUNCT
ct-9204	19	26	.	.	PUNCT
ct-9204	20	1	as	as	ADP
ct-9204	20	2	a	a	DET
ct-9204	20	3	result	result	NOUN
ct-9204	20	4	of	of	ADP
ct-9204	20	5	their	their	PRON
ct-9204	20	6	natural	natural	ADJ
ct-9204	20	7	in	in	ADP
ct-9204	20	8	vivo	vivo	ADJ
ct-9204	20	9	stability	stability	NOUN
ct-9204	20	10	,	,	PUNCT
ct-9204	20	11	cargo	cargo	NOUN
ct-9204	20	12	carrying	carry	VERB
ct-9204	20	13	capacity	capacity	NOUN
ct-9204	20	14	,	,	PUNCT
ct-9204	20	15	and	and	CCONJ
ct-9204	20	16	ability	ability	NOUN
ct-9204	20	17	to	to	PART
ct-9204	20	18	be	be	AUX
ct-9204	20	19	taken	take	VERB
ct-9204	20	20	up	up	ADP
ct-9204	20	21	by	by	ADP
ct-9204	20	22	cells	cell	NOUN
ct-9204	20	23	,	,	PUNCT
ct-9204	20	24	there	there	PRON
ct-9204	20	25	is	be	VERB
ct-9204	20	26	also	also	ADV
ct-9204	20	27	growing	grow	VERB
ct-9204	20	28	interest	interest	NOUN
ct-9204	20	29	in	in	ADP
ct-9204	20	30	utilizing	utilize	VERB
ct-9204	20	31	evs	evs	NOUN
ct-9204	20	32	for	for	ADP
ct-9204	20	33	in	in	ADP
ct-9204	20	34	vivo	vivo	ADJ
ct-9204	20	35	drug	drug	NOUN
ct-9204	20	36	and	and	CCONJ
ct-9204	20	37	therapeutic	therapeutic	ADJ
ct-9204	20	38	protein	protein	NOUN
ct-9204	20	39	delivery.24,25	delivery.24,25	NOUN
ct-9204	20	40	although	although	SCONJ
ct-9204	20	41	the	the	DET
ct-9204	20	42	field	field	NOUN
ct-9204	20	43	of	of	ADP
ct-9204	20	44	reproduction	reproduction	NOUN
ct-9204	20	45	-	-	PUNCT
ct-9204	20	46	specific	specific	ADJ
ct-9204	20	47	evs	evs	NOUN
ct-9204	20	48	is	be	AUX
ct-9204	20	49	still	still	ADV
ct-9204	20	50	relatively	relatively	ADV
ct-9204	20	51	new	new	ADJ
ct-9204	20	52	,	,	PUNCT
ct-9204	20	53	several	several	ADJ
ct-9204	20	54	excellent	excellent	ADJ
ct-9204	20	55	reviews	review	NOUN
ct-9204	20	56	published	publish	VERB
ct-9204	20	57	in	in	ADP
ct-9204	20	58	recent	recent	ADJ
ct-9204	20	59	years	year	NOUN
ct-9204	20	60	highlighted	highlight	VERB
ct-9204	20	61	growing	grow	VERB
ct-9204	20	62	interest	interest	NOUN
ct-9204	20	63	and	and	CCONJ
ct-9204	20	64	understanding	understanding	NOUN
ct-9204	20	65	of	of	ADP
ct-9204	20	66	roles	role	NOUN
ct-9204	20	67	of	of	ADP
ct-9204	20	68	evs	evs	NOUN
ct-9204	20	69	in	in	ADP
ct-9204	20	70	successful	successful	ADJ
ct-9204	20	71	gamete	gamete	NOUN
ct-9204	20	72	functions	function	NOUN
ct-9204	20	73	,	,	PUNCT
ct-9204	20	74	fertilization	fertilization	NOUN
ct-9204	20	75	,	,	PUNCT
ct-9204	20	76	embryo	embryo	NOUN
ct-9204	20	77	development	development	NOUN
ct-9204	20	78	,	,	PUNCT
ct-9204	20	79	and	and	CCONJ
ct-9204	20	80	pregnancy.26	pregnancy.26	ADJ
ct-9204	20	81	-	-	PUNCT
ct-9204	20	82	30	30	NUM
ct-9204	20	83	objectives	objective	NOUN
ct-9204	20	84	are	be	AUX
ct-9204	20	85	to	to	PART
ct-9204	20	86	outline	outline	VERB
ct-9204	20	87	current	current	ADJ
ct-9204	20	88	understanding	understanding	NOUN
ct-9204	20	89	of	of	ADP
ct-9204	20	90	evs	evs	NOUN
ct-9204	20	91	in	in	ADP
ct-9204	20	92	reproduction	reproduction	NOUN
ct-9204	20	93	,	,	PUNCT
ct-9204	20	94	including	include	VERB
ct-9204	20	95	recent	recent	ADJ
ct-9204	20	96	evaluations	evaluation	NOUN
ct-9204	20	97	of	of	ADP
ct-9204	20	98	reproductive	reproductive	ADJ
ct-9204	20	99	stage	stage	NOUN
ct-9204	20	100	on	on	ADP
ct-9204	20	101	ev	ev	INTJ
ct-9204	20	102	production	production	NOUN
ct-9204	20	103	and	and	CCONJ
ct-9204	20	104	composition	composition	NOUN
ct-9204	20	105	,	,	PUNCT
ct-9204	20	106	and	and	CCONJ
ct-9204	20	107	to	to	PART
ct-9204	20	108	discuss	discuss	VERB
ct-9204	20	109	potential	potential	ADJ
ct-9204	20	110	practical	practical	ADJ
ct-9204	20	111	/	/	SYM
ct-9204	20	112	therapeutic	therapeutic	ADJ
ct-9204	20	113	applications	application	NOUN
ct-9204	20	114	of	of	ADP
ct-9204	20	115	evs	evs	NOUN
ct-9204	20	116	in	in	ADP
ct-9204	20	117	assisted	assist	VERB
ct-9204	20	118	reproduction	reproduction	NOUN
ct-9204	20	119	,	,	PUNCT
ct-9204	20	120	with	with	ADP
ct-9204	20	121	a	a	DET
ct-9204	20	122	primary	primary	ADJ
ct-9204	20	123	focus	focus	NOUN
ct-9204	20	124	on	on	ADP
ct-9204	20	125	cryopreservation	cryopreservation	NOUN
ct-9204	20	126	.	.	PUNCT
ct-9204	21	1	figure	figure	NOUN
ct-9204	21	2	1	1	NUM
ct-9204	21	3	.	.	PUNCT
ct-9204	21	4	schematic	schematic	ADJ
ct-9204	21	5	of	of	ADP
ct-9204	21	6	extracellular	extracellular	ADJ
ct-9204	21	7	vesicle	vesicle	NOUN
ct-9204	21	8	(	(	PUNCT
ct-9204	21	9	ev	ev	NOUN
ct-9204	21	10	)	)	PUNCT
ct-9204	21	11	biogenesis	biogenesis	NOUN
ct-9204	21	12	and	and	CCONJ
ct-9204	21	13	composition	composition	NOUN
ct-9204	21	14	,	,	PUNCT
ct-9204	21	15	with	with	ADP
ct-9204	21	16	exosomes	exosome	NOUN
ct-9204	21	17	secreted	secrete	VERB
ct-9204	21	18	via	via	ADP
ct-9204	21	19	fusion	fusion	NOUN
ct-9204	21	20	of	of	ADP
ct-9204	21	21	multivesicle	multivesicle	NOUN
ct-9204	21	22	bodies	body	NOUN
ct-9204	21	23	from	from	ADP
ct-9204	21	24	early	early	ADJ
ct-9204	21	25	endosome	endosome	NOUN
ct-9204	21	26	fusing	fuse	VERB
ct-9204	21	27	with	with	ADP
ct-9204	21	28	cell	cell	NOUN
ct-9204	21	29	’s	’s	PART
ct-9204	21	30	plasma	plasma	NOUN
ct-9204	21	31	membrane	membrane	NOUN
ct-9204	21	32	,	,	PUNCT
ct-9204	21	33	microvesicles	microvesicle	NOUN
ct-9204	21	34	secreted	secrete	VERB
ct-9204	21	35	via	via	ADP
ct-9204	21	36	budding	budding	NOUN
ct-9204	21	37	,	,	PUNCT
ct-9204	21	38	and	and	CCONJ
ct-9204	21	39	apoptotic	apoptotic	ADJ
ct-9204	21	40	bodies	body	NOUN
ct-9204	21	41	released	release	VERB
ct-9204	21	42	via	via	ADP
ct-9204	21	43	blebbing	blebbe	VERB
ct-9204	21	44	.	.	PUNCT
ct-9204	22	1	collectively	collectively	ADV
ct-9204	22	2	termed	term	VERB
ct-9204	22	3	evs	evs	NOUN
ct-9204	22	4	,	,	PUNCT
ct-9204	22	5	these	these	DET
ct-9204	22	6	membrane	membrane	NOUN
ct-9204	22	7	-	-	PUNCT
ct-9204	22	8	bound	bind	VERB
ct-9204	22	9	vesicles	vesicle	NOUN
ct-9204	22	10	carry	carry	VERB
ct-9204	22	11	lipid	lipid	NOUN
ct-9204	22	12	,	,	PUNCT
ct-9204	22	13	rna	rna	NOUN
ct-9204	22	14	,	,	PUNCT
ct-9204	22	15	dna	dna	NOUN
ct-9204	22	16	,	,	PUNCT
ct-9204	22	17	and	and	CCONJ
ct-9204	22	18	protein	protein	NOUN
ct-9204	22	19	cargo	cargo	NOUN
ct-9204	22	20	from	from	ADP
ct-9204	22	21	their	their	PRON
ct-9204	22	22	cells	cell	NOUN
ct-9204	22	23	of	of	ADP
ct-9204	22	24	origin	origin	NOUN
ct-9204	22	25	.	.	PUNCT
ct-9204	23	1	clinical	clinical	ADJ
ct-9204	23	2	theriogenology	theriogenology	NOUN
ct-9204	23	3	•	•	NOUN
ct-9204	23	4	volume	volume	NOUN
ct-9204	23	5	12	12	NUM
ct-9204	23	6	number	number	NOUN
ct-9204	23	7	2	2	NUM
ct-9204	23	8	•	•	NOUN
ct-9204	23	9	june	june	PROPN
ct-9204	23	10	202090	202090	NUM
ct-9204	23	11	extracellular	extracellular	ADJ
ct-9204	23	12	vesicles	vesicle	NOUN
ct-9204	23	13	in	in	ADP
ct-9204	23	14	reproduction	reproduction	NOUN
ct-9204	23	15	overview	overview	NOUN
ct-9204	23	16	of	of	ADP
ct-9204	23	17	male	male	ADJ
ct-9204	23	18	reproductive	reproductive	ADJ
ct-9204	23	19	tract	tract	NOUN
ct-9204	23	20	extracellular	extracellular	ADJ
ct-9204	23	21	vesicles	vesicle	NOUN
ct-9204	23	22	to	to	ADP
ct-9204	23	23	date	date	NOUN
ct-9204	23	24	,	,	PUNCT
ct-9204	23	25	studies	study	NOUN
ct-9204	23	26	on	on	ADP
ct-9204	23	27	male	male	ADJ
ct-9204	23	28	reproductive	reproductive	ADJ
ct-9204	23	29	tract	tract	NOUN
ct-9204	23	30	evs	evs	NOUN
ct-9204	23	31	have	have	AUX
ct-9204	23	32	focused	focus	VERB
ct-9204	23	33	on	on	ADP
ct-9204	23	34	vesicles	vesicle	NOUN
ct-9204	23	35	derived	derive	VERB
ct-9204	23	36	from	from	ADP
ct-9204	23	37	epididymis	epididymis	NOUN
ct-9204	23	38	(	(	PUNCT
ct-9204	23	39	epididymosomes	epididymosome	NOUN
ct-9204	23	40	)	)	PUNCT
ct-9204	23	41	,	,	PUNCT
ct-9204	23	42	and	and	CCONJ
ct-9204	23	43	prostate	prostate	NOUN
ct-9204	23	44	gland	gland	NOUN
ct-9204	23	45	(	(	PUNCT
ct-9204	23	46	prostasomes	prostasome	NOUN
ct-9204	23	47	)	)	PUNCT
ct-9204	23	48	.	.	PUNCT
ct-9204	24	1	epididymosomes	epididymosome	NOUN
ct-9204	24	2	are	be	AUX
ct-9204	24	3	released	release	VERB
ct-9204	24	4	into	into	ADP
ct-9204	24	5	lumen	luman	NOUN
ct-9204	24	6	from	from	ADP
ct-9204	24	7	large	large	ADJ
ct-9204	24	8	blebs	blebs	NOUN
ct-9204	24	9	that	that	DET
ct-9204	24	10	form	form	NOUN
ct-9204	24	11	and	and	CCONJ
ct-9204	24	12	detach	detach	VERB
ct-9204	24	13	from	from	ADP
ct-9204	24	14	parent	parent	NOUN
ct-9204	24	15	epithelial	epithelial	ADJ
ct-9204	24	16	cells.31	cells.31	NOUN
ct-9204	24	17	epididymosomes	epididymosome	NOUN
ct-9204	24	18	fuse	fuse	NOUN
ct-9204	24	19	with	with	ADP
ct-9204	24	20	sperm	sperm	NOUN
ct-9204	24	21	during	during	ADP
ct-9204	24	22	their	their	PRON
ct-9204	24	23	transit	transit	NOUN
ct-9204	24	24	through	through	ADP
ct-9204	24	25	epididymis	epididymis	NOUN
ct-9204	24	26	and	and	CCONJ
ct-9204	24	27	deliver	deliver	VERB
ct-9204	24	28	small	small	ADJ
ct-9204	24	29	rna,32,33	rna,32,33	PROPN
ct-9204	24	30	and	and	CCONJ
ct-9204	24	31	protein	protein	NOUN
ct-9204	24	32	cargo,34,35	cargo,34,35	NOUN
ct-9204	24	33	and	and	CCONJ
ct-9204	24	34	alter	alter	VERB
ct-9204	24	35	lipid	lipid	NOUN
ct-9204	24	36	composition	composition	NOUN
ct-9204	24	37	of	of	ADP
ct-9204	24	38	sperm	sperm	NOUN
ct-9204	24	39	’s	’s	PART
ct-9204	24	40	plasma	plasma	NOUN
ct-9204	24	41	membrane,36	membrane,36	VERB
ct-9204	24	42	essential	essential	ADJ
ct-9204	24	43	for	for	ADP
ct-9204	24	44	sperm	sperm	NOUN
ct-9204	24	45	maturation	maturation	NOUN
ct-9204	24	46	process	process	NOUN
ct-9204	24	47	(	(	PUNCT
ct-9204	24	48	reviewed37	reviewed37	PROPN
ct-9204	24	49	)	)	PUNCT
ct-9204	24	50	.	.	PUNCT
ct-9204	25	1	specifically	specifically	ADV
ct-9204	25	2	,	,	PUNCT
ct-9204	25	3	epididymosomes	epididymosome	NOUN
ct-9204	25	4	reduce	reduce	VERB
ct-9204	25	5	cholesterol	cholesterol	NOUN
ct-9204	25	6	/	/	SYM
ct-9204	25	7	phospholipid	phospholipid	NOUN
ct-9204	25	8	ratio	ratio	NOUN
ct-9204	25	9	of	of	ADP
ct-9204	25	10	bovine	bovine	ADJ
ct-9204	25	11	caput	caput	NOUN
ct-9204	25	12	epididymal	epididymal	ADJ
ct-9204	25	13	sperm,36	sperm,36	NOUN
ct-9204	25	14	that	that	PRON
ct-9204	25	15	results	result	VERB
ct-9204	25	16	in	in	ADP
ct-9204	25	17	increased	increase	VERB
ct-9204	25	18	membrane	membrane	NOUN
ct-9204	25	19	fluidity	fluidity	NOUN
ct-9204	25	20	necessary	necessary	ADJ
ct-9204	25	21	for	for	ADP
ct-9204	25	22	the	the	DET
ct-9204	25	23	sperm	sperm	NOUN
ct-9204	25	24	’s	’s	PART
ct-9204	25	25	future	future	ADJ
ct-9204	25	26	ability	ability	NOUN
ct-9204	25	27	to	to	PART
ct-9204	25	28	capacitate	capacitate	VERB
ct-9204	25	29	.	.	PUNCT
ct-9204	26	1	gene	gene	NOUN
ct-9204	26	2	ontology	ontology	NOUN
ct-9204	26	3	analyses	analysis	NOUN
ct-9204	26	4	of	of	ADP
ct-9204	26	5	bovine	bovine	ADJ
ct-9204	26	6	epididymosomes	epididymosome	NOUN
ct-9204	26	7	classified	classify	VERB
ct-9204	26	8	proteins	protein	NOUN
ct-9204	26	9	into	into	ADP
ct-9204	26	10	6	6	NUM
ct-9204	26	11	functional	functional	ADJ
ct-9204	26	12	groups	group	NOUN
ct-9204	26	13	,	,	PUNCT
ct-9204	26	14	including	include	VERB
ct-9204	26	15	adhesion	adhesion	NOUN
ct-9204	26	16	molecules	molecule	NOUN
ct-9204	26	17	,	,	PUNCT
ct-9204	26	18	chaperones	chaperone	NOUN
ct-9204	26	19	,	,	PUNCT
ct-9204	26	20	enzymes	enzyme	NOUN
ct-9204	26	21	,	,	PUNCT
ct-9204	26	22	structural	structural	ADJ
ct-9204	26	23	proteins	protein	NOUN
ct-9204	26	24	,	,	PUNCT
ct-9204	26	25	signal	signal	NOUN
ct-9204	26	26	transducers	transducer	NOUN
ct-9204	26	27	,	,	PUNCT
ct-9204	26	28	and	and	CCONJ
ct-9204	26	29	transporters.37	transporters.37	VERB
ct-9204	26	30	many	many	ADJ
ct-9204	26	31	of	of	ADP
ct-9204	26	32	these	these	DET
ct-9204	26	33	proteins	protein	NOUN
ct-9204	26	34	are	be	AUX
ct-9204	26	35	involved	involve	VERB
ct-9204	26	36	in	in	ADP
ct-9204	26	37	sperm	sperm	NOUN
ct-9204	26	38	egg	egg	NOUN
ct-9204	26	39	interactions	interaction	NOUN
ct-9204	26	40	,	,	PUNCT
ct-9204	26	41	motility	motility	NOUN
ct-9204	26	42	,	,	PUNCT
ct-9204	26	43	plasma	plasma	NOUN
ct-9204	26	44	membrane	membrane	NOUN
ct-9204	26	45	modification	modification	NOUN
ct-9204	26	46	,	,	PUNCT
ct-9204	26	47	and	and	CCONJ
ct-9204	26	48	elimination	elimination	NOUN
ct-9204	26	49	of	of	ADP
ct-9204	26	50	defective	defective	ADJ
ct-9204	26	51	gametes.38	gametes.38	NOUN
ct-9204	26	52	transfer	transfer	NOUN
ct-9204	26	53	of	of	ADP
ct-9204	26	54	small	small	ADJ
ct-9204	26	55	rnas	rna	NOUN
ct-9204	26	56	(	(	PUNCT
ct-9204	26	57	e.g.	e.g.	ADV
ct-9204	26	58	mirna	mirna	NOUN
ct-9204	26	59	and	and	CCONJ
ct-9204	26	60	tsrna	tsrna	VERB
ct-9204	26	61	both	both	CCONJ
ct-9204	26	62	small	small	ADJ
ct-9204	26	63	,	,	PUNCT
ct-9204	26	64	noncoding	noncode	VERB
ct-9204	26	65	rna	rna	NOUN
ct-9204	26	66	that	that	PRON
ct-9204	26	67	primarily	primarily	ADV
ct-9204	26	68	function	function	VERB
ct-9204	26	69	in	in	ADP
ct-9204	26	70	rna	rna	NOUN
ct-9204	26	71	silencing	silencing	NOUN
ct-9204	26	72	and	and	CCONJ
ct-9204	26	73	posttranscriptional	posttranscriptional	ADJ
ct-9204	26	74	regulation39	regulation39	NOUN
ct-9204	26	75	)	)	PUNCT
ct-9204	26	76	from	from	ADP
ct-9204	26	77	epididymosomes	epididymosome	NOUN
ct-9204	26	78	to	to	ADP
ct-9204	26	79	sperm	sperm	NOUN
ct-9204	26	80	is	be	AUX
ct-9204	26	81	a	a	DET
ct-9204	26	82	mechanism	mechanism	NOUN
ct-9204	26	83	for	for	ADP
ct-9204	26	84	transgenerational	transgenerational	ADJ
ct-9204	26	85	epigenetic	epigenetic	ADJ
ct-9204	26	86	inheritance.32,40	inheritance.32,40	NOUN
ct-9204	26	87	coincubation	coincubation	NOUN
ct-9204	26	88	of	of	ADP
ct-9204	26	89	immature	immature	ADJ
ct-9204	26	90	sperm	sperm	NOUN
ct-9204	26	91	with	with	ADP
ct-9204	26	92	epididymosomes	epididymosome	NOUN
ct-9204	26	93	in	in	ADP
ct-9204	26	94	domestic	domestic	ADJ
ct-9204	26	95	cats	cat	NOUN
ct-9204	26	96	sustained	sustain	VERB
ct-9204	26	97	in	in	ADP
ct-9204	26	98	vitro	vitro	X
ct-9204	26	99	motility.41	motility.41	NOUN
ct-9204	26	100	delivered	deliver	VERB
ct-9204	26	101	mirna	mirna	NOUN
ct-9204	26	102	from	from	ADP
ct-9204	26	103	epididymal	epididymal	ADJ
ct-9204	26	104	evs	evs	NOUN
ct-9204	26	105	is	be	AUX
ct-9204	26	106	linked	link	VERB
ct-9204	26	107	to	to	ADP
ct-9204	26	108	pregnancy	pregnancy	NOUN
ct-9204	26	109	success	success	NOUN
ct-9204	26	110	in	in	ADP
ct-9204	26	111	mice	mouse	NOUN
ct-9204	26	112	,	,	PUNCT
ct-9204	26	113	as	as	SCONJ
ct-9204	26	114	intracytoplasmic	intracytoplasmic	ADJ
ct-9204	26	115	sperm	sperm	NOUN
ct-9204	26	116	injection	injection	NOUN
ct-9204	26	117	with	with	ADP
ct-9204	26	118	sperm	sperm	NOUN
ct-9204	26	119	from	from	ADP
ct-9204	26	120	caput	caput	NOUN
ct-9204	26	121	epididymis	epididymis	NOUN
ct-9204	26	122	displayed	display	VERB
ct-9204	26	123	significant	significant	ADJ
ct-9204	26	124	implantation	implantation	NOUN
ct-9204	26	125	failure	failure	NOUN
ct-9204	26	126	following	follow	VERB
ct-9204	26	127	embryo	embryo	NOUN
ct-9204	26	128	transfer	transfer	NOUN
ct-9204	26	129	;	;	PUNCT
ct-9204	26	130	a	a	DET
ct-9204	26	131	phenotype	phenotype	NOUN
ct-9204	26	132	rescued	rescue	VERB
ct-9204	26	133	by	by	ADP
ct-9204	26	134	injection	injection	NOUN
ct-9204	26	135	of	of	ADP
ct-9204	26	136	cauda	cauda	NOUN
ct-9204	26	137	-	-	PUNCT
ct-9204	26	138	specific	specific	ADJ
ct-9204	26	139	mirna	mirna	NOUN
ct-9204	26	140	into	into	ADP
ct-9204	26	141	embryos.42	embryos.42	NOUN
ct-9204	26	142	it	it	PRON
ct-9204	26	143	is	be	AUX
ct-9204	26	144	apparent	apparent	ADJ
ct-9204	26	145	that	that	SCONJ
ct-9204	26	146	these	these	DET
ct-9204	26	147	vesicles	vesicle	NOUN
ct-9204	26	148	have	have	VERB
ct-9204	26	149	a	a	DET
ct-9204	26	150	profound	profound	ADJ
ct-9204	26	151	influence	influence	NOUN
ct-9204	26	152	on	on	ADP
ct-9204	26	153	not	not	PART
ct-9204	26	154	only	only	ADV
ct-9204	26	155	male	male	ADJ
ct-9204	26	156	gametes	gamete	NOUN
ct-9204	26	157	,	,	PUNCT
ct-9204	26	158	but	but	CCONJ
ct-9204	26	159	also	also	ADV
ct-9204	26	160	pregnancy	pregnancy	NOUN
ct-9204	26	161	success	success	NOUN
ct-9204	26	162	and	and	CCONJ
ct-9204	26	163	,	,	PUNCT
ct-9204	26	164	potentially	potentially	ADV
ct-9204	26	165	,	,	PUNCT
ct-9204	26	166	offspring	offspring	NOUN
ct-9204	26	167	/	/	SYM
ct-9204	26	168	subsequent	subsequent	ADJ
ct-9204	26	169	generation	generation	NOUN
ct-9204	26	170	traits	trait	NOUN
ct-9204	26	171	via	via	ADP
ct-9204	26	172	epigenetic	epigenetic	ADJ
ct-9204	26	173	inheritance	inheritance	NOUN
ct-9204	26	174	.	.	PUNCT
ct-9204	27	1	prostasomes	prostasome	NOUN
ct-9204	27	2	(	(	PUNCT
ct-9204	27	3	reviewed43	reviewed43	PROPN
ct-9204	27	4	)	)	PUNCT
ct-9204	27	5	are	be	AUX
ct-9204	27	6	challenging	challenge	VERB
ct-9204	27	7	to	to	PART
ct-9204	27	8	characterize	characterize	VERB
ct-9204	27	9	,	,	PUNCT
ct-9204	27	10	as	as	SCONJ
ct-9204	27	11	they	they	PRON
ct-9204	27	12	are	be	AUX
ct-9204	27	13	mixed	mix	VERB
ct-9204	27	14	in	in	ADP
ct-9204	27	15	with	with	ADP
ct-9204	27	16	evs	evs	NOUN
ct-9204	27	17	from	from	ADP
ct-9204	27	18	other	other	ADJ
ct-9204	27	19	sources	source	NOUN
ct-9204	27	20	in	in	ADP
ct-9204	27	21	seminal	seminal	ADJ
ct-9204	27	22	fluids	fluid	NOUN
ct-9204	27	23	.	.	PUNCT
ct-9204	28	1	proteomic	proteomic	ADJ
ct-9204	28	2	analyses	analysis	NOUN
ct-9204	28	3	of	of	ADP
ct-9204	28	4	human	human	ADJ
ct-9204	28	5	prostasomes	prostasome	NOUN
ct-9204	28	6	identified	identify	VERB
ct-9204	28	7	proteins	protein	NOUN
ct-9204	28	8	in	in	ADP
ct-9204	28	9	broad	broad	ADJ
ct-9204	28	10	categories	category	NOUN
ct-9204	28	11	(	(	PUNCT
ct-9204	28	12	enzymes	enzyme	NOUN
ct-9204	28	13	,	,	PUNCT
ct-9204	28	14	transport	transport	NOUN
ct-9204	28	15	or	or	CCONJ
ct-9204	28	16	structural	structural	ADJ
ct-9204	28	17	integrity	integrity	NOUN
ct-9204	28	18	,	,	PUNCT
ct-9204	28	19	gtp	gtp	NOUN
ct-9204	28	20	proteins	protein	NOUN
ct-9204	28	21	,	,	PUNCT
ct-9204	28	22	chaperones	chaperone	NOUN
ct-9204	28	23	,	,	PUNCT
ct-9204	28	24	signal	signal	ADJ
ct-9204	28	25	transduction	transduction	NOUN
ct-9204	28	26	,	,	PUNCT
ct-9204	28	27	and	and	CCONJ
ct-9204	28	28	unannotated).44	unannotated).44	PROPN
ct-9204	28	29	supplementation	supplementation	NOUN
ct-9204	28	30	of	of	ADP
ct-9204	28	31	sperm	sperm	NOUN
ct-9204	28	32	with	with	ADP
ct-9204	28	33	prostasomes	prostasome	NOUN
ct-9204	28	34	improved	improve	VERB
ct-9204	28	35	sperm	sperm	NOUN
ct-9204	28	36	motility	motility	NOUN
ct-9204	28	37	,	,	PUNCT
ct-9204	28	38	attributed	attribute	VERB
ct-9204	28	39	to	to	ADP
ct-9204	28	40	delivery	delivery	NOUN
ct-9204	28	41	of	of	ADP
ct-9204	28	42	calcium	calcium	NOUN
ct-9204	28	43	signaling45	signaling45	NOUN
ct-9204	28	44	and	and	CCONJ
ct-9204	28	45	atp	atp	PROPN
ct-9204	28	46	-	-	PUNCT
ct-9204	28	47	generating46	generating46	NOUN
ct-9204	28	48	machinery	machinery	NOUN
ct-9204	28	49	to	to	ADP
ct-9204	28	50	the	the	DET
ct-9204	28	51	gamete	gamete	NOUN
ct-9204	28	52	.	.	PUNCT
ct-9204	29	1	human	human	ADJ
ct-9204	29	2	prostasome	prostasome	NOUN
ct-9204	29	3	membranes	membrane	NOUN
ct-9204	29	4	are	be	AUX
ct-9204	29	5	high	high	ADJ
ct-9204	29	6	in	in	ADP
ct-9204	29	7	cholesterol	cholesterol	NOUN
ct-9204	29	8	,	,	PUNCT
ct-9204	29	9	sphingomyelin	sphingomyelin	NOUN
ct-9204	29	10	and	and	CCONJ
ct-9204	29	11	glycosphingolipids.47,48	glycosphingolipids.47,48	ADJ
ct-9204	29	12	fusion	fusion	NOUN
ct-9204	29	13	with	with	ADP
ct-9204	29	14	prostasomes	prostasome	NOUN
ct-9204	29	15	enriched	enrich	VERB
ct-9204	29	16	sperm	sperm	NOUN
ct-9204	29	17	’s	’s	PART
ct-9204	29	18	plasma	plasma	NOUN
ct-9204	29	19	membranes	membrane	NOUN
ct-9204	29	20	in	in	ADP
ct-9204	29	21	key	key	ADJ
ct-9204	29	22	lipids	lipid	NOUN
ct-9204	29	23	,	,	PUNCT
ct-9204	29	24	including	include	VERB
ct-9204	29	25	cholesterol.49	cholesterol.49	NOUN
ct-9204	29	26	this	this	PRON
ct-9204	29	27	,	,	PUNCT
ct-9204	29	28	in	in	ADP
ct-9204	29	29	turn	turn	NOUN
ct-9204	29	30	,	,	PUNCT
ct-9204	29	31	is	be	AUX
ct-9204	29	32	apparently	apparently	ADV
ct-9204	29	33	responsible	responsible	ADJ
ct-9204	29	34	for	for	ADP
ct-9204	29	35	the	the	DET
ct-9204	29	36	prevention	prevention	NOUN
ct-9204	29	37	of	of	ADP
ct-9204	29	38	premature	premature	ADJ
ct-9204	29	39	acrosomal	acrosomal	NOUN
ct-9204	29	40	exocytosis	exocytosis	NOUN
ct-9204	29	41	in	in	ADP
ct-9204	29	42	sperm	sperm	NOUN
ct-9204	29	43	exposed	expose	VERB
ct-9204	29	44	to	to	ADP
ct-9204	29	45	prostasomes	prostasome	NOUN
ct-9204	29	46	in	in	ADP
ct-9204	29	47	cattle50	cattle50	NOUN
ct-9204	29	48	and	and	CCONJ
ct-9204	29	49	humans.51,52	humans.51,52	NOUN
ct-9204	29	50	prostasomes	prostasome	NOUN
ct-9204	29	51	also	also	ADV
ct-9204	29	52	protect	protect	VERB
ct-9204	29	53	sperm	sperm	NOUN
ct-9204	29	54	against	against	ADP
ct-9204	29	55	female	female	ADJ
ct-9204	29	56	immune	immune	ADJ
ct-9204	29	57	system	system	NOUN
ct-9204	29	58	,	,	PUNCT
ct-9204	29	59	including	include	VERB
ct-9204	29	60	decreasing	decrease	VERB
ct-9204	29	61	natural	natural	ADJ
ct-9204	29	62	killer	killer	NOUN
ct-9204	29	63	cell	cell	NOUN
ct-9204	29	64	activity	activity	NOUN
ct-9204	29	65	in	in	ADP
ct-9204	29	66	vitro,53	vitro,53	NOUN
ct-9204	29	67	indicating	indicate	VERB
ct-9204	29	68	prostasomes	prostasome	NOUN
ct-9204	29	69	function	function	VERB
ct-9204	29	70	both	both	PRON
ct-9204	29	71	to	to	PART
ct-9204	29	72	maintain	maintain	VERB
ct-9204	29	73	sperm	sperm	NOUN
ct-9204	29	74	function	function	NOUN
ct-9204	29	75	and	and	CCONJ
ct-9204	29	76	support	support	NOUN
ct-9204	29	77	survival	survival	NOUN
ct-9204	29	78	.	.	PUNCT
ct-9204	30	1	overview	overview	NOUN
ct-9204	30	2	of	of	ADP
ct-9204	30	3	female	female	ADJ
ct-9204	30	4	reproductive	reproductive	ADJ
ct-9204	30	5	tract	tract	NOUN
ct-9204	30	6	extracellular	extracellular	ADJ
ct-9204	30	7	vesicles	vesicle	NOUN
ct-9204	30	8	extracellular	extracellular	ADJ
ct-9204	30	9	vesicles	vesicle	NOUN
ct-9204	30	10	derived	derive	VERB
ct-9204	30	11	from	from	ADP
ct-9204	30	12	vaginal	vaginal	ADJ
ct-9204	30	13	(	(	PUNCT
ct-9204	30	14	vaginosomes54	vaginosomes54	PROPN
ct-9204	30	15	)	)	PUNCT
ct-9204	30	16	,	,	PUNCT
ct-9204	30	17	uterine	uterine	NOUN
ct-9204	30	18	(	(	PUNCT
ct-9204	30	19	uterosomes	uterosome	NOUN
ct-9204	30	20	,	,	PUNCT
ct-9204	30	21	reviewed	review	VERB
ct-9204	30	22	55,56	55,56	NOUN
ct-9204	30	23	)	)	PUNCT
ct-9204	30	24	,	,	PUNCT
ct-9204	30	25	oviductal	oviductal	ADJ
ct-9204	30	26	(	(	PUNCT
ct-9204	30	27	oviductosomes	oviductosomes	ADJ
ct-9204	30	28	or	or	CCONJ
ct-9204	30	29	oevs	oevs	ADJ
ct-9204	30	30	,	,	PUNCT
ct-9204	30	31	reviewed27	reviewed27	NOUN
ct-9204	30	32	)	)	PUNCT
ct-9204	30	33	and	and	CCONJ
ct-9204	30	34	follicular	follicular	ADJ
ct-9204	30	35	(	(	PUNCT
ct-9204	30	36	ffevs	ffevs	NOUN
ct-9204	30	37	,	,	PUNCT
ct-9204	30	38	reviewed30,57,58	reviewed30,57,58	NOUN
ct-9204	30	39	)	)	PUNCT
ct-9204	30	40	,	,	PUNCT
ct-9204	30	41	fluids	fluid	NOUN
ct-9204	30	42	,	,	PUNCT
ct-9204	30	43	and	and	CCONJ
ct-9204	30	44	secretions	secretion	NOUN
ct-9204	30	45	from	from	ADP
ct-9204	30	46	in	in	ADP
ct-9204	30	47	vitro	vitro	X
ct-9204	30	48	cultured	cultured	ADJ
ct-9204	30	49	embryos	embryo	NOUN
ct-9204	30	50	(	(	PUNCT
ct-9204	30	51	reviewed59	reviewed59	PROPN
ct-9204	30	52	)	)	PUNCT
ct-9204	30	53	are	be	AUX
ct-9204	30	54	characterized	characterize	VERB
ct-9204	30	55	in	in	ADP
ct-9204	30	56	a	a	DET
ct-9204	30	57	variety	variety	NOUN
ct-9204	30	58	of	of	ADP
ct-9204	30	59	species	specie	NOUN
ct-9204	30	60	.	.	PUNCT
ct-9204	31	1	supplementation	supplementation	NOUN
ct-9204	31	2	of	of	ADP
ct-9204	31	3	evs	evs	NOUN
ct-9204	31	4	from	from	ADP
ct-9204	31	5	these	these	DET
ct-9204	31	6	sources	source	NOUN
ct-9204	31	7	benefit	benefit	VERB
ct-9204	31	8	gamete	gamete	NOUN
ct-9204	31	9	function	function	NOUN
ct-9204	31	10	and/or	and/or	CCONJ
ct-9204	31	11	embryo	embryo	NOUN
ct-9204	31	12	development	development	NOUN
ct-9204	31	13	.	.	PUNCT
ct-9204	32	1	for	for	ADP
ct-9204	32	2	example	example	NOUN
ct-9204	32	3	,	,	PUNCT
ct-9204	32	4	coincubation	coincubation	NOUN
ct-9204	32	5	of	of	ADP
ct-9204	32	6	vaginal	vaginal	ADJ
ct-9204	32	7	evs	evs	NOUN
ct-9204	32	8	with	with	ADP
ct-9204	32	9	murine	murine	ADJ
ct-9204	32	10	sperm	sperm	NOUN
ct-9204	32	11	increased	increase	VERB
ct-9204	32	12	rates	rate	NOUN
ct-9204	32	13	of	of	ADP
ct-9204	32	14	progesterone	progesterone	NOUN
ct-9204	32	15	-	-	PUNCT
ct-9204	32	16	induced	induce	VERB
ct-9204	32	17	acrosome	acrosome	NOUN
ct-9204	32	18	exocytosis	exocytosis	NOUN
ct-9204	32	19	compared	compare	VERB
ct-9204	32	20	to	to	ADP
ct-9204	32	21	unsupplemented	unsupplemented	ADJ
ct-9204	32	22	controls.54	controls.54	NOUN
ct-9204	32	23	this	this	DET
ct-9204	32	24	effect	effect	NOUN
ct-9204	32	25	was	be	AUX
ct-9204	32	26	attributed	attribute	VERB
ct-9204	32	27	to	to	ADP
ct-9204	32	28	transfer	transfer	NOUN
ct-9204	32	29	of	of	ADP
ct-9204	32	30	tyrosine	tyrosine	NOUN
ct-9204	32	31	phosphorylated	phosphorylate	VERB
ct-9204	32	32	proteins	protein	NOUN
ct-9204	32	33	and	and	CCONJ
ct-9204	32	34	plasma	plasma	NOUN
ct-9204	32	35	membrane	membrane	NOUN
ct-9204	32	36	ca2	ca2	PROPN
ct-9204	32	37	+	+	PROPN
ct-9204	32	38	atpase	atpase	PROPN
ct-9204	32	39	(	(	PUNCT
ct-9204	32	40	[	[	X
ct-9204	32	41	pmca	pmca	NOUN
ct-9204	32	42	]	]	PUNCT
ct-9204	32	43	,	,	PUNCT
ct-9204	32	44	which	which	PRON
ct-9204	32	45	removes	remove	VERB
ct-9204	32	46	calcium	calcium	NOUN
ct-9204	32	47	from	from	ADP
ct-9204	32	48	cells	cell	NOUN
ct-9204	32	49	)	)	PUNCT
ct-9204	32	50	from	from	ADP
ct-9204	32	51	evs	evs	NOUN
ct-9204	32	52	to	to	ADP
ct-9204	32	53	sperm	sperm	NOUN
ct-9204	32	54	,	,	PUNCT
ct-9204	32	55	essentially	essentially	ADV
ct-9204	32	56	priming	prime	VERB
ct-9204	32	57	cells	cell	NOUN
ct-9204	32	58	for	for	ADP
ct-9204	32	59	capacitation	capacitation	NOUN
ct-9204	32	60	while	while	SCONJ
ct-9204	32	61	preventing	prevent	VERB
ct-9204	32	62	premature	premature	ADJ
ct-9204	32	63	acrosome	acrosome	NOUN
ct-9204	32	64	reaction	reaction	NOUN
ct-9204	32	65	.	.	PUNCT
ct-9204	33	1	endometrial	endometrial	ADJ
ct-9204	33	2	mesenchymal	mesenchymal	NOUN
ct-9204	33	3	stem	stem	NOUN
ct-9204	33	4	cell	cell	NOUN
ct-9204	33	5	evs	evs	NOUN
ct-9204	33	6	improved	improve	VERB
ct-9204	33	7	blastomere	blastomere	ADJ
ct-9204	33	8	count	count	NOUN
ct-9204	33	9	and	and	CCONJ
ct-9204	33	10	hatching	hatch	VERB
ct-9204	33	11	rates	rate	NOUN
ct-9204	33	12	in	in	ADP
ct-9204	33	13	murine	murine	ADJ
ct-9204	33	14	embryos.60	embryos.60	PROPN
ct-9204	33	15	coincubation	coincubation	NOUN
ct-9204	33	16	with	with	ADP
ct-9204	33	17	evs	evs	PROPN
ct-9204	33	18	also	also	ADV
ct-9204	33	19	stimulated	stimulate	VERB
ct-9204	33	20	embryos	embryo	NOUN
ct-9204	33	21	to	to	PART
ct-9204	33	22	release	release	VERB
ct-9204	33	23	vascular	vascular	ADJ
ct-9204	33	24	endothelial	endothelial	ADJ
ct-9204	33	25	growth	growth	NOUN
ct-9204	33	26	factor	factor	NOUN
ct-9204	33	27	and	and	CCONJ
ct-9204	33	28	platelet	platelet	NOUN
ct-9204	33	29	derived	derived	ADJ
ct-9204	33	30	growth	growth	NOUN
ct-9204	33	31	factor	factor	NOUN
ct-9204	33	32	,	,	PUNCT
ct-9204	33	33	which	which	PRON
ct-9204	33	34	in	in	ADP
ct-9204	33	35	turn	turn	NOUN
ct-9204	33	36	may	may	AUX
ct-9204	33	37	modulate	modulate	VERB
ct-9204	33	38	endometrial	endometrial	ADJ
ct-9204	33	39	receptivity	receptivity	NOUN
ct-9204	33	40	to	to	ADP
ct-9204	33	41	implantation.60	implantation.60	VERB
ct-9204	33	42	our	our	PRON
ct-9204	33	43	laboratory	laboratory	NOUN
ct-9204	33	44	recently	recently	ADV
ct-9204	33	45	demonstrated	demonstrate	VERB
ct-9204	33	46	that	that	SCONJ
ct-9204	33	47	domestic	domestic	ADJ
ct-9204	33	48	cat	cat	NOUN
ct-9204	33	49	oviductal	oviductal	ADJ
ct-9204	33	50	extracellular	extracellular	ADJ
ct-9204	33	51	vesicles	vesicle	NOUN
ct-9204	33	52	(	(	PUNCT
ct-9204	33	53	oevs	oevs	ADJ
ct-9204	33	54	)	)	PUNCT
ct-9204	33	55	bound	bind	VERB
ct-9204	33	56	to	to	ADP
ct-9204	33	57	acrosomal	acrosomal	NOUN
ct-9204	33	58	region	region	NOUN
ct-9204	33	59	and	and	CCONJ
ct-9204	33	60	midpiece	midpiece	NOUN
ct-9204	33	61	of	of	ADP
ct-9204	33	62	sperm	sperm	NOUN
ct-9204	33	63	and	and	CCONJ
ct-9204	33	64	prevented	prevent	VERB
ct-9204	33	65	premature	premature	ADJ
ct-9204	33	66	acrosomal	acrosomal	NOUN
ct-9204	33	67	exocytosis	exocytosis	NOUN
ct-9204	33	68	(	(	PUNCT
ct-9204	33	69	in	in	ADP
ct-9204	33	70	vitro	vitro	X
ct-9204	33	71	)	)	PUNCT
ct-9204	33	72	,	,	PUNCT
ct-9204	33	73	while	while	SCONJ
ct-9204	33	74	improving	improve	VERB
ct-9204	33	75	sperm	sperm	NOUN
ct-9204	33	76	motility	motility	NOUN
ct-9204	33	77	and	and	CCONJ
ct-9204	33	78	fertilizing	fertilize	VERB
ct-9204	33	79	capacity61	capacity61	NOUN
ct-9204	33	80	(	(	PUNCT
ct-9204	33	81	figure	figure	NOUN
ct-9204	33	82	2	2	NUM
ct-9204	33	83	)	)	PUNCT
ct-9204	33	84	.	.	PUNCT
ct-9204	34	1	we	we	PRON
ct-9204	34	2	postulated	postulate	VERB
ct-9204	34	3	that	that	DET
ct-9204	34	4	enrichment	enrichment	NOUN
ct-9204	34	5	in	in	ADP
ct-9204	34	6	proteins	protein	NOUN
ct-9204	34	7	identified	identify	VERB
ct-9204	34	8	in	in	ADP
ct-9204	34	9	oevs	oevs	NOUN
ct-9204	34	10	was	be	AUX
ct-9204	34	11	related	relate	VERB
ct-9204	34	12	to	to	ADP
ct-9204	34	13	energy	energy	NOUN
ct-9204	34	14	metabolism	metabolism	NOUN
ct-9204	34	15	,	,	PUNCT
ct-9204	34	16	calcium	calcium	NOUN
ct-9204	34	17	transport	transport	NOUN
ct-9204	34	18	and	and	CCONJ
ct-9204	34	19	clinical	clinical	ADJ
ct-9204	34	20	theriogenology	theriogenology	NOUN
ct-9204	34	21	•	•	NOUN
ct-9204	34	22	volume	volume	NOUN
ct-9204	34	23	12	12	NUM
ct-9204	34	24	number	number	NOUN
ct-9204	34	25	2	2	NUM
ct-9204	34	26	•	•	NOUN
ct-9204	34	27	june	june	PROPN
ct-9204	34	28	2020	2020	NUM
ct-9204	34	29	91	91	NUM
ct-9204	34	30	membrane	membrane	NOUN
ct-9204	34	31	function	function	NOUN
ct-9204	34	32	,	,	PUNCT
ct-9204	34	33	may	may	AUX
ct-9204	34	34	have	have	AUX
ct-9204	34	35	regulated	regulate	VERB
ct-9204	34	36	this	this	DET
ct-9204	34	37	effect	effect	NOUN
ct-9204	34	38	.	.	PUNCT
ct-9204	35	1	in	in	ADP
ct-9204	35	2	cattle	cattle	NOUN
ct-9204	35	3	,	,	PUNCT
ct-9204	35	4	oevs	oevs	NOUN
ct-9204	35	5	modulate	modulate	VERB
ct-9204	35	6	sperm	sperm	NOUN
ct-9204	35	7	calcium	calcium	NOUN
ct-9204	35	8	concentrations62	concentrations62	NOUN
ct-9204	35	9	and	and	CCONJ
ct-9204	35	10	they	they	PRON
ct-9204	35	11	also	also	ADV
ct-9204	35	12	modulated	modulate	VERB
ct-9204	35	13	sperm	sperm	NOUN
ct-9204	35	14	capacitation	capacitation	NOUN
ct-9204	35	15	in	in	ADP
ct-9204	35	16	cattle	cattle	NOUN
ct-9204	35	17	and	and	CCONJ
ct-9204	35	18	mice.62,63	mice.62,63	ADJ
ct-9204	35	19	porcine	porcine	NOUN
ct-9204	35	20	oevs	oevs	NOUN
ct-9204	35	21	reduced	reduce	VERB
ct-9204	35	22	rates	rate	NOUN
ct-9204	35	23	of	of	ADP
ct-9204	35	24	polyspermy	polyspermy	NOUN
ct-9204	35	25	in	in	ADP
ct-9204	35	26	vitro,64	vitro,64	NOUN
ct-9204	35	27	and	and	CCONJ
ct-9204	35	28	murine	murine	ADJ
ct-9204	35	29	oev	oev	NOUN
ct-9204	35	30	supplementation	supplementation	NOUN
ct-9204	35	31	during	during	ADP
ct-9204	35	32	in	in	ADP
ct-9204	35	33	vitro	vitro	X
ct-9204	35	34	fertilization	fertilization	NOUN
ct-9204	35	35	and	and	CCONJ
ct-9204	35	36	embryo	embryo	NOUN
ct-9204	35	37	culture	culture	NOUN
ct-9204	35	38	improved	improve	VERB
ct-9204	35	39	live	live	ADJ
ct-9204	35	40	birth	birth	NOUN
ct-9204	35	41	rates	rate	NOUN
ct-9204	35	42	after	after	ADP
ct-9204	35	43	embryo	embryo	NOUN
ct-9204	35	44	transfer.65	transfer.65	PROPN
ct-9204	35	45	hence	hence	ADV
ct-9204	35	46	,	,	PUNCT
ct-9204	35	47	recently	recently	ADV
ct-9204	35	48	,	,	PUNCT
ct-9204	35	49	oevs	oevs	NOUN
ct-9204	35	50	have	have	AUX
ct-9204	35	51	been	be	AUX
ct-9204	35	52	utilized	utilize	VERB
ct-9204	35	53	to	to	PART
ct-9204	35	54	improve	improve	VERB
ct-9204	35	55	in	in	ADP
ct-9204	35	56	vitro	vitro	X
ct-9204	35	57	embryo	embryo	NOUN
ct-9204	35	58	production	production	NOUN
ct-9204	35	59	technologies.27	technologies.27	PROPN
ct-9204	35	60	follicular	follicular	ADJ
ct-9204	35	61	fluid	fluid	NOUN
ct-9204	35	62	evs	evs	NOUN
ct-9204	35	63	,	,	PUNCT
ct-9204	35	64	apparently	apparently	ADV
ct-9204	35	65	produced	produce	VERB
ct-9204	35	66	by	by	ADP
ct-9204	35	67	granulosa	granulosa	NOUN
ct-9204	35	68	and	and	CCONJ
ct-9204	35	69	cumulus	cumulus	NOUN
ct-9204	35	70	cells	cell	NOUN
ct-9204	35	71	,	,	PUNCT
ct-9204	35	72	are	be	AUX
ct-9204	35	73	taken	take	VERB
ct-9204	35	74	up	up	ADP
ct-9204	35	75	into	into	ADP
ct-9204	35	76	cumulus	cumulus	NOUN
ct-9204	35	77	cell	cell	NOUN
ct-9204	35	78	layer	layer	NOUN
ct-9204	35	79	of	of	ADP
ct-9204	35	80	domestic	domestic	ADJ
ct-9204	35	81	cat	cat	NOUN
ct-9204	35	82	oocytes	oocyte	NOUN
ct-9204	35	83	(	(	PUNCT
ct-9204	35	84	figure	figure	NOUN
ct-9204	35	85	2	2	NUM
ct-9204	35	86	)	)	PUNCT
ct-9204	35	87	and	and	CCONJ
ct-9204	35	88	,	,	PUNCT
ct-9204	35	89	in	in	ADP
ct-9204	35	90	cattle	cattle	NOUN
ct-9204	35	91	,	,	PUNCT
ct-9204	35	92	transferred	transfer	VERB
ct-9204	35	93	to	to	ADP
ct-9204	35	94	an	an	DET
ct-9204	35	95	oocyte	oocyte	NOUN
ct-9204	35	96	via	via	ADP
ct-9204	35	97	transzonal	transzonal	ADJ
ct-9204	35	98	projections.66	projections.66	NOUN
ct-9204	35	99	bovine	bovine	PROPN
ct-9204	35	100	ffevs	ffevs	NOUN
ct-9204	35	101	stimulated	stimulate	VERB
ct-9204	35	102	granulosa	granulosa	NOUN
ct-9204	35	103	cell	cell	NOUN
ct-9204	35	104	proliferation67	proliferation67	NOUN
ct-9204	35	105	and	and	CCONJ
ct-9204	35	106	cumulus	cumulus	NOUN
ct-9204	35	107	cell	cell	NOUN
ct-9204	35	108	expansion,68	expansion,68	VERB
ct-9204	35	109	and	and	CCONJ
ct-9204	35	110	improved	improved	ADJ
ct-9204	35	111	blastocyst	blastocyst	NOUN
ct-9204	35	112	production.68	production.68	PROPN
ct-9204	35	113	bovine	bovine	PROPN
ct-9204	35	114	embryos	embryo	NOUN
ct-9204	35	115	produced	produce	VERB
ct-9204	35	116	in	in	ADP
ct-9204	35	117	vitro	vitro	X
ct-9204	35	118	in	in	ADP
ct-9204	35	119	the	the	DET
ct-9204	35	120	presence	presence	NOUN
ct-9204	35	121	of	of	ADP
ct-9204	35	122	ffevs	ffevs	NOUN
ct-9204	35	123	exhibited	exhibit	VERB
ct-9204	35	124	varying	vary	VERB
ct-9204	35	125	levels	level	NOUN
ct-9204	35	126	of	of	ADP
ct-9204	35	127	global	global	ADJ
ct-9204	35	128	dna	dna	PROPN
ct-9204	35	129	methylation	methylation	NOUN
ct-9204	35	130	compared	compare	VERB
ct-9204	35	131	to	to	PART
ct-9204	35	132	nonffev	nonffev	VERB
ct-9204	35	133	counterparts.69	counterparts.69	PROPN
ct-9204	35	134	taken	take	VERB
ct-9204	35	135	together	together	ADV
ct-9204	35	136	,	,	PUNCT
ct-9204	35	137	it	it	PRON
ct-9204	35	138	is	be	AUX
ct-9204	35	139	clear	clear	ADJ
ct-9204	35	140	that	that	SCONJ
ct-9204	35	141	supplementation	supplementation	NOUN
ct-9204	35	142	of	of	ADP
ct-9204	35	143	evs	evs	NOUN
ct-9204	35	144	to	to	AUX
ct-9204	35	145	in	in	ADP
ct-9204	35	146	vitro	vitro	X
ct-9204	35	147	embryo	embryo	NOUN
ct-9204	35	148	production	production	NOUN
ct-9204	35	149	systems	system	NOUN
ct-9204	35	150	promises	promise	NOUN
ct-9204	35	151	to	to	PART
ct-9204	35	152	improve	improve	VERB
ct-9204	35	153	not	not	PART
ct-9204	35	154	only	only	ADV
ct-9204	35	155	production	production	NOUN
ct-9204	35	156	rates	rate	NOUN
ct-9204	35	157	,	,	PUNCT
ct-9204	35	158	but	but	CCONJ
ct-9204	35	159	also	also	ADV
ct-9204	35	160	embryo	embryo	NOUN
ct-9204	35	161	quality	quality	NOUN
ct-9204	35	162	and	and	CCONJ
ct-9204	35	163	potentially	potentially	ADV
ct-9204	35	164	live	live	VERB
ct-9204	35	165	birth	birth	NOUN
ct-9204	35	166	success	success	NOUN
ct-9204	35	167	.	.	PUNCT
ct-9204	36	1	extracellular	extracellular	ADJ
ct-9204	36	2	vesicles	vesicle	NOUN
ct-9204	36	3	and	and	CCONJ
ct-9204	36	4	reproductive	reproductive	ADJ
ct-9204	36	5	cycles	cycle	NOUN
ct-9204	36	6	despite	despite	SCONJ
ct-9204	36	7	strong	strong	ADJ
ct-9204	36	8	evidence	evidence	NOUN
ct-9204	36	9	of	of	ADP
ct-9204	36	10	beneficial	beneficial	ADJ
ct-9204	36	11	actions	action	NOUN
ct-9204	36	12	of	of	ADP
ct-9204	36	13	evs	evs	NOUN
ct-9204	36	14	on	on	ADP
ct-9204	36	15	reproduction	reproduction	NOUN
ct-9204	36	16	,	,	PUNCT
ct-9204	36	17	our	our	PRON
ct-9204	36	18	understanding	understanding	NOUN
ct-9204	36	19	of	of	ADP
ct-9204	36	20	how	how	SCONJ
ct-9204	36	21	ev	ev	ADP
ct-9204	36	22	biogenesis	biogenesis	NOUN
ct-9204	36	23	and	and	CCONJ
ct-9204	36	24	composition	composition	NOUN
ct-9204	36	25	are	be	AUX
ct-9204	36	26	modulated	modulate	VERB
ct-9204	36	27	by	by	ADP
ct-9204	36	28	reproductive	reproductive	ADJ
ct-9204	36	29	cycle	cycle	NOUN
ct-9204	36	30	is	be	AUX
ct-9204	36	31	limited	limited	ADJ
ct-9204	36	32	.	.	PUNCT
ct-9204	37	1	nevertheless	nevertheless	ADV
ct-9204	37	2	,	,	PUNCT
ct-9204	37	3	there	there	PRON
ct-9204	37	4	is	be	VERB
ct-9204	37	5	evidence	evidence	NOUN
ct-9204	37	6	that	that	SCONJ
ct-9204	37	7	changes	change	NOUN
ct-9204	37	8	in	in	ADP
ct-9204	37	9	secreted	secreted	ADJ
ct-9204	37	10	evs	evs	NOUN
ct-9204	37	11	are	be	AUX
ct-9204	37	12	under	under	ADP
ct-9204	37	13	hormonal	hormonal	ADJ
ct-9204	37	14	control.66,70	control.66,70	NOUN
ct-9204	37	15	-	-	PUNCT
ct-9204	37	16	73	73	NUM
ct-9204	37	17	for	for	ADP
ct-9204	37	18	example	example	NOUN
ct-9204	37	19	,	,	PUNCT
ct-9204	37	20	ovariectomized	ovariectomize	VERB
ct-9204	37	21	sheep	sheep	NOUN
ct-9204	37	22	treated	treat	VERB
ct-9204	37	23	with	with	ADP
ct-9204	37	24	progesterone	progesterone	NOUN
ct-9204	37	25	for	for	ADP
ct-9204	37	26	14	14	NUM
ct-9204	37	27	days	day	NOUN
ct-9204	37	28	had	have	VERB
ct-9204	37	29	higher	high	ADJ
ct-9204	37	30	ev	ev	ADP
ct-9204	37	31	count	count	NOUN
ct-9204	37	32	(	(	PUNCT
ct-9204	37	33	based	base	VERB
ct-9204	37	34	on	on	ADP
ct-9204	37	35	nta	nta	PROPN
ct-9204	37	36	)	)	PUNCT
ct-9204	37	37	and	and	CCONJ
ct-9204	37	38	mode	mode	NOUN
ct-9204	37	39	diameter	diameter	NOUN
ct-9204	37	40	in	in	ADP
ct-9204	37	41	their	their	PRON
ct-9204	37	42	uterine	uterine	ADJ
ct-9204	37	43	fluid	fluid	NOUN
ct-9204	37	44	compared	compare	VERB
ct-9204	37	45	to	to	ADP
ct-9204	37	46	untreated	untreated	ADJ
ct-9204	37	47	cohorts	cohort	NOUN
ct-9204	37	48	,	,	PUNCT
ct-9204	37	49	indicating	indicate	VERB
ct-9204	37	50	biogenesis	biogenesis	NOUN
ct-9204	37	51	and	and	CCONJ
ct-9204	37	52	secretion	secretion	NOUN
ct-9204	37	53	of	of	ADP
ct-9204	37	54	endometrial	endometrial	ADJ
ct-9204	37	55	evs	evs	NOUN
ct-9204	37	56	were	be	AUX
ct-9204	37	57	modulated	modulate	VERB
ct-9204	37	58	by	by	ADP
ct-9204	37	59	progesterone.71	progesterone.71	NOUN
ct-9204	37	60	in	in	ADP
ct-9204	37	61	an	an	DET
ct-9204	37	62	in	in	X
ct-9204	37	63	vitro	vitro	X
ct-9204	37	64	study	study	NOUN
ct-9204	37	65	with	with	ADP
ct-9204	37	66	primary	primary	ADJ
ct-9204	37	67	cell	cell	NOUN
ct-9204	37	68	cultures	culture	NOUN
ct-9204	37	69	of	of	ADP
ct-9204	37	70	human	human	ADJ
ct-9204	37	71	endometrial	endometrial	ADJ
ct-9204	37	72	epithelial	epithelial	ADJ
ct-9204	37	73	cell	cell	NOUN
ct-9204	37	74	lines	line	NOUN
ct-9204	37	75	,	,	PUNCT
ct-9204	37	76	there	there	PRON
ct-9204	37	77	were	be	VERB
ct-9204	37	78	no	no	DET
ct-9204	37	79	differences	difference	NOUN
ct-9204	37	80	in	in	ADP
ct-9204	37	81	ev	ev	ADP
ct-9204	37	82	amounts	amount	NOUN
ct-9204	37	83	(	(	PUNCT
ct-9204	37	84	based	base	VERB
ct-9204	37	85	on	on	ADP
ct-9204	37	86	protein	protein	NOUN
ct-9204	37	87	concentrations	concentration	NOUN
ct-9204	37	88	)	)	PUNCT
ct-9204	37	89	from	from	ADP
ct-9204	37	90	cells	cell	NOUN
ct-9204	37	91	cultured	cultured	ADJ
ct-9204	37	92	only	only	ADV
ct-9204	37	93	with	with	ADP
ct-9204	37	94	estrogen	estrogen	NOUN
ct-9204	37	95	(	(	PUNCT
ct-9204	37	96	i.e.	i.e.	X
ct-9204	37	97	proliferative	proliferative	ADJ
ct-9204	37	98	phase	phase	NOUN
ct-9204	37	99	-	-	PUNCT
ct-9204	37	100	mimetic	mimetic	NOUN
ct-9204	37	101	)	)	PUNCT
ct-9204	37	102	versus	versus	ADP
ct-9204	37	103	estrogen	estrogen	NOUN
ct-9204	37	104	and	and	CCONJ
ct-9204	37	105	progesterone	progesterone	NOUN
ct-9204	37	106	(	(	PUNCT
ct-9204	37	107	i.e.	i.e.	X
ct-9204	37	108	secretory	secretory	ADJ
ct-9204	37	109	phase	phase	NOUN
ct-9204	37	110	mimetic).72	mimetic).72	PROPN
ct-9204	37	111	however	however	ADV
ct-9204	37	112	,	,	PUNCT
ct-9204	37	113	there	there	PRON
ct-9204	37	114	were	be	VERB
ct-9204	37	115	380	380	NUM
ct-9204	37	116	differentially	differentially	ADV
ct-9204	37	117	expressed	express	VERB
ct-9204	37	118	proteins	protein	NOUN
ct-9204	37	119	between	between	ADP
ct-9204	37	120	evs	evs	NOUN
ct-9204	37	121	of	of	ADP
ct-9204	37	122	2	2	NUM
ct-9204	37	123	treatment	treatment	NOUN
ct-9204	37	124	groups	group	NOUN
ct-9204	37	125	,	,	PUNCT
ct-9204	37	126	many	many	ADJ
ct-9204	37	127	of	of	ADP
ct-9204	37	128	which	which	PRON
ct-9204	37	129	were	be	AUX
ct-9204	37	130	involved	involve	VERB
ct-9204	37	131	in	in	ADP
ct-9204	37	132	cytoskeletal	cytoskeletal	ADJ
ct-9204	37	133	organization	organization	NOUN
ct-9204	37	134	,	,	PUNCT
ct-9204	37	135	cell	cell	NOUN
ct-9204	37	136	migration	migration	NOUN
ct-9204	37	137	,	,	PUNCT
ct-9204	37	138	cell	cell	NOUN
ct-9204	37	139	adhesion	adhesion	NOUN
ct-9204	37	140	,	,	PUNCT
ct-9204	37	141	and	and	CCONJ
ct-9204	37	142	extracellular	extracellular	ADJ
ct-9204	37	143	matrix	matrix	NOUN
ct-9204	37	144	organization	organization	NOUN
ct-9204	37	145	.	.	PUNCT
ct-9204	38	1	these	these	DET
ct-9204	38	2	studies	study	NOUN
ct-9204	38	3	indicated	indicate	VERB
ct-9204	38	4	that	that	SCONJ
ct-9204	38	5	uterine	uterine	NOUN
ct-9204	38	6	ev	ev	INTJ
ct-9204	38	7	production	production	NOUN
ct-9204	38	8	and	and	CCONJ
ct-9204	38	9	their	their	PRON
ct-9204	38	10	protein	protein	NOUN
ct-9204	38	11	compositions	composition	NOUN
ct-9204	38	12	are	be	AUX
ct-9204	38	13	under	under	ADP
ct-9204	38	14	hormonal	hormonal	ADJ
ct-9204	38	15	control	control	NOUN
ct-9204	38	16	.	.	PUNCT
ct-9204	39	1	figure	figure	NOUN
ct-9204	39	2	2	2	NUM
ct-9204	39	3	.	.	PUNCT
ct-9204	39	4	schematic	schematic	ADJ
ct-9204	39	5	of	of	ADP
ct-9204	39	6	female	female	ADJ
ct-9204	39	7	reproductive	reproductive	ADJ
ct-9204	39	8	tract	tract	NOUN
ct-9204	39	9	evs	evs	NOUN
ct-9204	39	10	and	and	CCONJ
ct-9204	39	11	interaction	interaction	NOUN
ct-9204	39	12	with	with	ADP
ct-9204	39	13	gametes	gamete	NOUN
ct-9204	39	14	/	/	SYM
ct-9204	39	15	embryos	embryo	NOUN
ct-9204	39	16	,	,	PUNCT
ct-9204	39	17	including	include	VERB
ct-9204	39	18	pre	pre	VERB
ct-9204	39	19	-	-	ADJ
ct-9204	39	20	release	release	ADJ
ct-9204	39	21	uterosomes	uterosome	NOUN
ct-9204	39	22	in	in	ADP
ct-9204	39	23	a	a	DET
ct-9204	39	24	multivesicular	multivesicular	ADJ
ct-9204	39	25	body	body	NOUN
ct-9204	39	26	in	in	ADP
ct-9204	39	27	ovine	ovine	ADJ
ct-9204	39	28	endometrial	endometrial	ADJ
ct-9204	39	29	luminal	luminal	ADJ
ct-9204	39	30	epithelium	epithelium	NOUN
ct-9204	39	31	(	(	PUNCT
ct-9204	39	32	top	top	NOUN
ct-9204	39	33	left	left	ADJ
ct-9204	39	34	,	,	PUNCT
ct-9204	39	35	tem	tem	PROPN
ct-9204	39	36	image	image	NOUN
ct-9204	39	37	from	from	ADP
ct-9204	39	38	burns	burn	NOUN
ct-9204	39	39	et	et	PROPN
ct-9204	39	40	al	al	PROPN
ct-9204	39	41	2016	2016	NUM
ct-9204	39	42	)	)	PUNCT
ct-9204	39	43	,	,	PUNCT
ct-9204	39	44	oviductosomes	oviductosome	NOUN
ct-9204	39	45	or	or	CCONJ
ct-9204	39	46	oev	oev	NOUN
ct-9204	39	47	from	from	ADP
ct-9204	39	48	domestic	domestic	ADJ
ct-9204	39	49	cats	cat	NOUN
ct-9204	39	50	(	(	PUNCT
ct-9204	39	51	lower	low	ADJ
ct-9204	39	52	middle	middle	ADJ
ct-9204	39	53	,	,	PUNCT
ct-9204	39	54	tem	tem	PROPN
ct-9204	39	55	image	image	NOUN
ct-9204	39	56	fusing	fuse	VERB
ct-9204	39	57	with	with	ADP
ct-9204	39	58	sperm	sperm	NOUN
ct-9204	39	59	tail	tail	NOUN
ct-9204	39	60	from	from	ADP
ct-9204	39	61	ferraz	ferraz	PROPN
ct-9204	39	62	et	et	NOUN
ct-9204	39	63	al	al	PROPN
ct-9204	39	64	2019	2019	NUM
ct-9204	39	65	)	)	PUNCT
ct-9204	39	66	,	,	PUNCT
ct-9204	39	67	and	and	CCONJ
ct-9204	39	68	feline	feline	ADJ
ct-9204	39	69	follicular	follicular	ADJ
ct-9204	39	70	fluid	fluid	NOUN
ct-9204	39	71	(	(	PUNCT
ct-9204	39	72	top	top	ADJ
ct-9204	39	73	middle	middle	ADJ
ct-9204	39	74	,	,	PUNCT
ct-9204	39	75	fluorescent	fluorescent	ADJ
ct-9204	39	76	image	image	NOUN
ct-9204	39	77	with	with	ADP
ct-9204	39	78	ev	ev	X
ct-9204	39	79	lipids	lipid	NOUN
ct-9204	39	80	labeled	label	VERB
ct-9204	39	81	in	in	ADP
ct-9204	39	82	green	green	ADJ
ct-9204	39	83	(	(	PUNCT
ct-9204	39	84	dio	dio	NOUN
ct-9204	39	85	)	)	PUNCT
ct-9204	39	86	and	and	CCONJ
ct-9204	39	87	ev	ev	INTJ
ct-9204	39	88	proteins	protein	NOUN
ct-9204	39	89	in	in	ADP
ct-9204	39	90	blue	blue	ADJ
ct-9204	39	91	(	(	PUNCT
ct-9204	39	92	ghost	ghost	NOUN
ct-9204	39	93	dye	dye	NOUN
ct-9204	39	94	)	)	PUNCT
ct-9204	39	95	taken	take	VERB
ct-9204	39	96	up	up	ADP
ct-9204	39	97	by	by	ADP
ct-9204	39	98	cumulus	cumulus	NOUN
ct-9204	39	99	cells	cell	NOUN
ct-9204	39	100	,	,	PUNCT
ct-9204	39	101	manuscript	manuscript	NOUN
ct-9204	39	102	under	under	ADP
ct-9204	39	103	review	review	NOUN
ct-9204	39	104	)	)	PUNCT
ct-9204	39	105	clinical	clinical	ADJ
ct-9204	39	106	theriogenology	theriogenology	NOUN
ct-9204	39	107	•	•	NOUN
ct-9204	39	108	volume	volume	NOUN
ct-9204	39	109	12	12	NUM
ct-9204	39	110	number	number	NOUN
ct-9204	39	111	2	2	NUM
ct-9204	39	112	•	•	NOUN
ct-9204	39	113	june	june	PROPN
ct-9204	39	114	202092	202092	NUM
ct-9204	39	115	recently	recently	ADV
ct-9204	39	116	,	,	PUNCT
ct-9204	39	117	counts	count	NOUN
ct-9204	39	118	,	,	PUNCT
ct-9204	39	119	transcriptomes	transcriptome	NOUN
ct-9204	39	120	,	,	PUNCT
ct-9204	39	121	and	and	CCONJ
ct-9204	39	122	proteomes	proteome	NOUN
ct-9204	39	123	of	of	ADP
ct-9204	39	124	oevs	oevs	PROPN
ct-9204	39	125	recovered	recover	VERB
ct-9204	39	126	during	during	ADP
ct-9204	39	127	various	various	ADJ
ct-9204	39	128	stages	stage	NOUN
ct-9204	39	129	of	of	ADP
ct-9204	39	130	reproductive	reproductive	ADJ
ct-9204	39	131	cycles	cycle	NOUN
ct-9204	39	132	have	have	AUX
ct-9204	39	133	been	be	AUX
ct-9204	39	134	characterized	characterize	VERB
ct-9204	39	135	in	in	ADP
ct-9204	39	136	several	several	ADJ
ct-9204	39	137	mammalian	mammalian	ADJ
ct-9204	39	138	species	specie	NOUN
ct-9204	39	139	.	.	PUNCT
ct-9204	40	1	in	in	ADP
ct-9204	40	2	murine	murine	ADJ
ct-9204	40	3	oev	oev	NOUN
ct-9204	40	4	,	,	PUNCT
ct-9204	40	5	very	very	ADV
ct-9204	40	6	few	few	ADJ
ct-9204	40	7	differences	difference	NOUN
ct-9204	40	8	in	in	ADP
ct-9204	40	9	mirna	mirna	PROPN
ct-9204	40	10	content	content	NOUN
ct-9204	40	11	were	be	AUX
ct-9204	40	12	observed	observe	VERB
ct-9204	40	13	among	among	ADP
ct-9204	40	14	reproductive	reproductive	ADJ
ct-9204	40	15	stages	stage	NOUN
ct-9204	40	16	(	(	PUNCT
ct-9204	40	17	metestrus	metestrus	NOUN
ct-9204	40	18	/	/	SYM
ct-9204	40	19	diestrus	diestrus	NOUN
ct-9204	40	20	versus	versus	ADP
ct-9204	40	21	proestrus	proestrus	NOUN
ct-9204	40	22	/	/	SYM
ct-9204	40	23	estrus).73	estrus).73	PROPN
ct-9204	40	24	in	in	ADP
ct-9204	40	25	domestic	domestic	ADJ
ct-9204	40	26	cats	cat	NOUN
ct-9204	40	27	,	,	PUNCT
ct-9204	40	28	we	we	PRON
ct-9204	40	29	observed	observe	VERB
ct-9204	40	30	an	an	DET
ct-9204	40	31	increase	increase	NOUN
ct-9204	40	32	in	in	ADP
ct-9204	40	33	concentration	concentration	NOUN
ct-9204	40	34	,	,	PUNCT
ct-9204	40	35	but	but	CCONJ
ct-9204	40	36	not	not	PART
ct-9204	40	37	size	size	NOUN
ct-9204	40	38	distribution	distribution	NOUN
ct-9204	40	39	,	,	PUNCT
ct-9204	40	40	in	in	ADP
ct-9204	40	41	oevs	oevs	NOUN
ct-9204	40	42	recovered	recover	VERB
ct-9204	40	43	during	during	ADP
ct-9204	40	44	midluteal	midluteal	ADJ
ct-9204	40	45	phase	phase	NOUN
ct-9204	40	46	compared	compare	VERB
ct-9204	40	47	to	to	ADP
ct-9204	40	48	early	early	ADJ
ct-9204	40	49	luteal	luteal	ADJ
ct-9204	40	50	and	and	CCONJ
ct-9204	40	51	late	late	ADJ
ct-9204	40	52	follicular	follicular	ADJ
ct-9204	40	53	phases	phase	NOUN
ct-9204	40	54	(	(	PUNCT
ct-9204	40	55	manuscript	manuscript	NOUN
ct-9204	40	56	under	under	ADP
ct-9204	40	57	review	review	NOUN
ct-9204	40	58	)	)	PUNCT
ct-9204	40	59	.	.	PUNCT
ct-9204	41	1	conversely	conversely	ADV
ct-9204	41	2	,	,	PUNCT
ct-9204	41	3	protein	protein	NOUN
ct-9204	41	4	and	and	CCONJ
ct-9204	41	5	mrna	mrna	PROPN
ct-9204	41	6	/	/	SYM
ct-9204	41	7	small	small	ADJ
ct-9204	41	8	rna	rna	NOUN
ct-9204	41	9	content	content	NOUN
ct-9204	41	10	of	of	ADP
ct-9204	41	11	bovine	bovine	ADJ
ct-9204	41	12	oev	oev	NOUN
ct-9204	41	13	isolated	isolate	VERB
ct-9204	41	14	during	during	ADP
ct-9204	41	15	postovulatory	postovulatory	ADJ
ct-9204	41	16	and	and	CCONJ
ct-9204	41	17	early	early	ADJ
ct-9204	41	18	luteal	luteal	ADJ
ct-9204	41	19	phases	phase	NOUN
ct-9204	41	20	were	be	AUX
ct-9204	41	21	enriched	enrich	VERB
ct-9204	41	22	in	in	ADP
ct-9204	41	23	proteins	protein	NOUN
ct-9204	41	24	related	relate	VERB
ct-9204	41	25	to	to	ADP
ct-9204	41	26	protein	protein	NOUN
ct-9204	41	27	translation	translation	NOUN
ct-9204	41	28	and	and	CCONJ
ct-9204	41	29	transport	transport	NOUN
ct-9204	41	30	,	,	PUNCT
ct-9204	41	31	whereas	whereas	SCONJ
ct-9204	41	32	those	those	PRON
ct-9204	41	33	obtained	obtain	VERB
ct-9204	41	34	during	during	ADP
ct-9204	41	35	late	late	ADJ
ct-9204	41	36	luteal	luteal	ADJ
ct-9204	41	37	phase	phase	NOUN
ct-9204	41	38	contained	contain	VERB
ct-9204	41	39	proteins	protein	NOUN
ct-9204	41	40	related	relate	VERB
ct-9204	41	41	to	to	ADP
ct-9204	41	42	vesicles	vesicle	NOUN
ct-9204	41	43	,	,	PUNCT
ct-9204	41	44	cytoskeleton	cytoskeleton	NOUN
ct-9204	41	45	,	,	PUNCT
ct-9204	41	46	metalloexopeptidase	metalloexopeptidase	NOUN
ct-9204	41	47	activity	activity	NOUN
ct-9204	41	48	,	,	PUNCT
ct-9204	41	49	and	and	CCONJ
ct-9204	41	50	innate	innate	ADJ
ct-9204	41	51	immune	immune	ADJ
ct-9204	41	52	system.70	system.70	NOUN
ct-9204	41	53	furthermore	furthermore	ADV
ct-9204	41	54	,	,	PUNCT
ct-9204	41	55	mirna	mirna	PROPN
ct-9204	41	56	with	with	ADP
ct-9204	41	57	high	high	ADJ
ct-9204	41	58	abundance	abundance	NOUN
ct-9204	41	59	in	in	ADP
ct-9204	41	60	recently	recently	ADV
ct-9204	41	61	ovulated	ovulate	VERB
ct-9204	41	62	and	and	CCONJ
ct-9204	41	63	late	late	ADJ
ct-9204	41	64	luteal	luteal	ADJ
ct-9204	41	65	phase	phase	NOUN
ct-9204	41	66	included	include	VERB
ct-9204	41	67	those	those	PRON
ct-9204	41	68	involved	involve	VERB
ct-9204	41	69	in	in	ADP
ct-9204	41	70	fatty	fatty	NOUN
ct-9204	41	71	acid	acid	NOUN
ct-9204	41	72	biosynthesis	biosynthesis	NOUN
ct-9204	41	73	and	and	CCONJ
ct-9204	41	74	metabolism	metabolism	NOUN
ct-9204	41	75	,	,	PUNCT
ct-9204	41	76	cell	cell	NOUN
ct-9204	41	77	cycle	cycle	NOUN
ct-9204	41	78	,	,	PUNCT
ct-9204	41	79	oocyte	oocyte	ADJ
ct-9204	41	80	meiosis	meiosis	NOUN
ct-9204	41	81	,	,	PUNCT
ct-9204	41	82	and	and	CCONJ
ct-9204	41	83	multiple	multiple	ADJ
ct-9204	41	84	signaling	signal	VERB
ct-9204	41	85	pathways.70	pathways.70	NOUN
ct-9204	41	86	these	these	DET
ct-9204	41	87	results	result	NOUN
ct-9204	41	88	were	be	AUX
ct-9204	41	89	further	further	ADJ
ct-9204	41	90	evidence	evidence	NOUN
ct-9204	41	91	for	for	ADP
ct-9204	41	92	potential	potential	ADJ
ct-9204	41	93	targeted	target	VERB
ct-9204	41	94	messaging	messaging	NOUN
ct-9204	41	95	to	to	ADP
ct-9204	41	96	gametes	gamete	NOUN
ct-9204	41	97	and/or	and/or	CCONJ
ct-9204	41	98	embryos	embryo	NOUN
ct-9204	41	99	to	to	PART
ct-9204	41	100	promote	promote	VERB
ct-9204	41	101	fertilization	fertilization	NOUN
ct-9204	41	102	and	and	CCONJ
ct-9204	41	103	development	development	NOUN
ct-9204	41	104	by	by	ADP
ct-9204	41	105	reproductive	reproductive	ADJ
ct-9204	41	106	tract	tract	NOUN
ct-9204	41	107	.	.	PUNCT
ct-9204	42	1	also	also	ADV
ct-9204	42	2	in	in	ADP
ct-9204	42	3	a	a	DET
ct-9204	42	4	bovine	bovine	NOUN
ct-9204	42	5	model	model	NOUN
ct-9204	42	6	,	,	PUNCT
ct-9204	42	7	mirna	mirna	PROPN
ct-9204	42	8	from	from	ADP
ct-9204	42	9	ffev	ffev	PROPN
ct-9204	42	10	of	of	ADP
ct-9204	42	11	3	3	NUM
ct-9204	42	12	6	6	NUM
ct-9204	42	13	mm	mm	NOUN
ct-9204	42	14	diameter	diameter	NOUN
ct-9204	42	15	follicles	follicle	NOUN
ct-9204	42	16	at	at	ADP
ct-9204	42	17	various	various	ADJ
ct-9204	42	18	stages	stage	NOUN
ct-9204	42	19	of	of	ADP
ct-9204	42	20	the	the	DET
ct-9204	42	21	estrous	estrous	ADJ
ct-9204	42	22	cycle	cycle	NOUN
ct-9204	42	23	were	be	AUX
ct-9204	42	24	compared.66	compared.66	ADP
ct-9204	42	25	follicular	follicular	ADJ
ct-9204	42	26	fluid	fluid	NOUN
ct-9204	42	27	evs	evs	NOUN
ct-9204	42	28	from	from	ADP
ct-9204	42	29	early	early	ADJ
ct-9204	42	30	luteal	luteal	ADJ
ct-9204	42	31	ovaries	ovary	NOUN
ct-9204	42	32	(	(	PUNCT
ct-9204	42	33	with	with	SCONJ
ct-9204	42	34	evidence	evidence	NOUN
ct-9204	42	35	of	of	ADP
ct-9204	42	36	recent	recent	ADJ
ct-9204	42	37	ovulation	ovulation	NOUN
ct-9204	42	38	,	,	PUNCT
ct-9204	42	39	low	low	ADJ
ct-9204	42	40	follicular	follicular	ADJ
ct-9204	42	41	fluid	fluid	NOUN
ct-9204	42	42	progesterone	progesterone	NOUN
ct-9204	42	43	concentration	concentration	NOUN
ct-9204	42	44	)	)	PUNCT
ct-9204	42	45	were	be	AUX
ct-9204	42	46	enriched	enrich	VERB
ct-9204	42	47	in	in	ADP
ct-9204	42	48	mirna	mirna	NOUN
ct-9204	42	49	involved	involve	VERB
ct-9204	42	50	in	in	ADP
ct-9204	42	51	multiple	multiple	ADJ
ct-9204	42	52	signaling	signal	VERB
ct-9204	42	53	pathways	pathway	NOUN
ct-9204	42	54	,	,	PUNCT
ct-9204	42	55	including	include	VERB
ct-9204	42	56	foxo	foxo	PROPN
ct-9204	42	57	,	,	PUNCT
ct-9204	42	58	hippo	hippo	NOUN
ct-9204	42	59	,	,	PUNCT
ct-9204	42	60	mapk	mapk	NOUN
ct-9204	42	61	,	,	PUNCT
ct-9204	42	62	and	and	CCONJ
ct-9204	42	63	tgfβ	tgfβ	NOUN
ct-9204	42	64	compared	compare	VERB
ct-9204	42	65	to	to	PART
ct-9204	42	66	ffevs	ffevs	VERB
ct-9204	42	67	from	from	ADP
ct-9204	42	68	midluteal	midluteal	ADJ
ct-9204	42	69	phase	phase	NOUN
ct-9204	42	70	ovaries	ovary	NOUN
ct-9204	42	71	(	(	PUNCT
ct-9204	42	72	tan	tan	NOUN
ct-9204	42	73	corpus	corpus	PROPN
ct-9204	42	74	luteum	luteum	NOUN
ct-9204	42	75	,	,	PUNCT
ct-9204	42	76	high	high	ADJ
ct-9204	42	77	progesterone).66	progesterone).66	X
ct-9204	42	78	when	when	SCONJ
ct-9204	42	79	early	early	ADJ
ct-9204	42	80	luteal	luteal	ADJ
ct-9204	42	81	phase	phase	NOUN
ct-9204	42	82	ffevs	ffevs	NOUN
ct-9204	42	83	were	be	AUX
ct-9204	42	84	supplemented	supplement	VERB
ct-9204	42	85	to	to	ADP
ct-9204	42	86	culture	culture	NOUN
ct-9204	42	87	media	medium	NOUN
ct-9204	42	88	during	during	ADP
ct-9204	42	89	24	24	NUM
ct-9204	42	90	hour	hour	NOUN
ct-9204	42	91	in	in	ADP
ct-9204	42	92	vitro	vitro	X
ct-9204	42	93	oocyte	oocyte	ADJ
ct-9204	42	94	maturation	maturation	NOUN
ct-9204	42	95	,	,	PUNCT
ct-9204	42	96	expression	expression	NOUN
ct-9204	42	97	of	of	ADP
ct-9204	42	98	genes	gene	NOUN
ct-9204	42	99	associated	associate	VERB
ct-9204	42	100	with	with	ADP
ct-9204	42	101	pathways	pathway	NOUN
ct-9204	42	102	related	relate	VERB
ct-9204	42	103	to	to	ADP
ct-9204	42	104	oocyte	oocyte	ADJ
ct-9204	42	105	development	development	NOUN
ct-9204	42	106	,	,	PUNCT
ct-9204	42	107	ovulation	ovulation	NOUN
ct-9204	42	108	,	,	PUNCT
ct-9204	42	109	and	and	CCONJ
ct-9204	42	110	notch	notch	NOUN
ct-9204	42	111	signaling	signal	VERB
ct-9204	42	112	were	be	AUX
ct-9204	42	113	upregulated	upregulate	VERB
ct-9204	42	114	in	in	ADP
ct-9204	42	115	cumulus	cumulus	NOUN
ct-9204	42	116	cells	cell	NOUN
ct-9204	42	117	,	,	PUNCT
ct-9204	42	118	indicating	indicate	VERB
ct-9204	42	119	that	that	SCONJ
ct-9204	42	120	reproductive	reproductive	ADJ
ct-9204	42	121	stage	stage	NOUN
ct-9204	42	122	specific	specific	ADJ
ct-9204	42	123	cargo	cargo	NOUN
ct-9204	42	124	of	of	ADP
ct-9204	42	125	ffevs	ffevs	NOUN
ct-9204	42	126	may	may	AUX
ct-9204	42	127	have	have	VERB
ct-9204	42	128	key	key	ADJ
ct-9204	42	129	roles	role	NOUN
ct-9204	42	130	in	in	ADP
ct-9204	42	131	regulating	regulate	VERB
ct-9204	42	132	gamete	gamete	NOUN
ct-9204	42	133	function	function	NOUN
ct-9204	42	134	.	.	PUNCT
ct-9204	43	1	more	more	ADV
ct-9204	43	2	tangentially	tangentially	ADV
ct-9204	43	3	,	,	PUNCT
ct-9204	43	4	there	there	PRON
ct-9204	43	5	is	be	VERB
ct-9204	43	6	also	also	ADV
ct-9204	43	7	evidence	evidence	NOUN
ct-9204	43	8	linking	link	VERB
ct-9204	43	9	metabolic	metabolic	NOUN
ct-9204	43	10	status	status	NOUN
ct-9204	43	11	as	as	ADP
ct-9204	43	12	result	result	NOUN
ct-9204	43	13	of	of	ADP
ct-9204	43	14	lactation	lactation	NOUN
ct-9204	43	15	to	to	ADP
ct-9204	43	16	mirna	mirna	VERB
ct-9204	43	17	composition	composition	NOUN
ct-9204	43	18	of	of	ADP
ct-9204	43	19	bovine	bovine	ADJ
ct-9204	43	20	follicular	follicular	ADJ
ct-9204	43	21	fluid	fluid	NOUN
ct-9204	43	22	evs.74	evs.74	NOUN
ct-9204	43	23	namely	namely	ADV
ct-9204	43	24	,	,	PUNCT
ct-9204	43	25	cows	cow	NOUN
ct-9204	43	26	in	in	ADP
ct-9204	43	27	negative	negative	ADJ
ct-9204	43	28	energy	energy	NOUN
ct-9204	43	29	balance	balance	NOUN
ct-9204	43	30	had	have	VERB
ct-9204	43	31	ffev	ffev	NOUN
ct-9204	43	32	with	with	ADP
ct-9204	43	33	downregulation	downregulation	NOUN
ct-9204	43	34	of	of	ADP
ct-9204	43	35	mirna	mirna	NOUN
ct-9204	43	36	associated	associate	VERB
ct-9204	43	37	with	with	ADP
ct-9204	43	38	metabolic	metabolic	NOUN
ct-9204	43	39	processes	process	NOUN
ct-9204	43	40	and	and	CCONJ
ct-9204	43	41	oocyte	oocyte	ADJ
ct-9204	43	42	growth	growth	NOUN
ct-9204	43	43	compared	compare	VERB
ct-9204	43	44	to	to	ADP
ct-9204	43	45	metabolically	metabolically	VERB
ct-9204	43	46	normal	normal	ADJ
ct-9204	43	47	lactating	lactating	NOUN
ct-9204	43	48	heifers	heifer	NOUN
ct-9204	43	49	,	,	PUNCT
ct-9204	43	50	which	which	PRON
ct-9204	43	51	has	have	VERB
ct-9204	43	52	implications	implication	NOUN
ct-9204	43	53	for	for	ADP
ct-9204	43	54	folliculogenesis	folliculogenesis	NOUN
ct-9204	43	55	during	during	ADP
ct-9204	43	56	lactational	lactational	ADJ
ct-9204	43	57	anestrus	anestrus	NOUN
ct-9204	43	58	.	.	PUNCT
ct-9204	44	1	although	although	SCONJ
ct-9204	44	2	in	in	ADP
ct-9204	44	3	the	the	DET
ct-9204	44	4	earlier	early	ADJ
ct-9204	44	5	bovine	bovine	PROPN
ct-9204	44	6	ffev	ffev	PROPN
ct-9204	44	7	study	study	NOUN
ct-9204	44	8	,	,	PUNCT
ct-9204	44	9	supplementing	supplement	VERB
ct-9204	44	10	ffevs	ffevs	NOUN
ct-9204	44	11	during	during	ADP
ct-9204	44	12	ivm	ivm	PROPN
ct-9204	44	13	upregulated	upregulate	VERB
ct-9204	44	14	gene	gene	NOUN
ct-9204	44	15	expression	expression	NOUN
ct-9204	44	16	in	in	ADP
ct-9204	44	17	the	the	DET
ct-9204	44	18	cumulus	cumulus	NOUN
ct-9204	44	19	cell	cell	NOUN
ct-9204	44	20	,	,	PUNCT
ct-9204	44	21	no	no	DET
ct-9204	44	22	differences	difference	NOUN
ct-9204	44	23	in	in	ADP
ct-9204	44	24	oocyte	oocyte	ADJ
ct-9204	44	25	maturation	maturation	NOUN
ct-9204	44	26	rates	rate	NOUN
ct-9204	44	27	were	be	AUX
ct-9204	44	28	observed	observe	VERB
ct-9204	44	29	between	between	ADP
ct-9204	44	30	ffevs	ffevs	NOUN
ct-9204	44	31	gametes	gamete	NOUN
ct-9204	44	32	versus	versus	ADP
ct-9204	44	33	controls.66	controls.66	PROPN
ct-9204	44	34	it	it	PRON
ct-9204	44	35	is	be	AUX
ct-9204	44	36	possible	possible	ADJ
ct-9204	44	37	that	that	SCONJ
ct-9204	44	38	24	24	NUM
ct-9204	44	39	hour	hour	NOUN
ct-9204	44	40	time	time	NOUN
ct-9204	44	41	frame	frame	NOUN
ct-9204	44	42	of	of	ADP
ct-9204	44	43	ivm	ivm	PROPN
ct-9204	44	44	was	be	AUX
ct-9204	44	45	not	not	PART
ct-9204	44	46	long	long	ADJ
ct-9204	44	47	enough	enough	ADV
ct-9204	44	48	to	to	PART
ct-9204	44	49	facilitate	facilitate	VERB
ct-9204	44	50	transfer	transfer	NOUN
ct-9204	44	51	of	of	ADP
ct-9204	44	52	ev	ev	ADP
ct-9204	44	53	cargo	cargo	NOUN
ct-9204	44	54	into	into	ADP
ct-9204	44	55	the	the	DET
ct-9204	44	56	oocyte	oocyte	NOUN
ct-9204	44	57	and	and	CCONJ
ct-9204	44	58	influence	influence	NOUN
ct-9204	44	59	meiotic	meiotic	ADJ
ct-9204	44	60	maturation	maturation	NOUN
ct-9204	44	61	outcome	outcome	NOUN
ct-9204	44	62	.	.	PUNCT
ct-9204	45	1	in	in	ADP
ct-9204	45	2	another	another	DET
ct-9204	45	3	bovine	bovine	NOUN
ct-9204	45	4	study	study	NOUN
ct-9204	45	5	,	,	PUNCT
ct-9204	45	6	ffevs	ffevs	PROPN
ct-9204	45	7	were	be	AUX
ct-9204	45	8	detected	detect	VERB
ct-9204	45	9	in	in	ADP
ct-9204	45	10	cumulus	cumulus	NOUN
ct-9204	45	11	cells	cell	NOUN
ct-9204	45	12	via	via	ADP
ct-9204	45	13	confocal	confocal	ADJ
ct-9204	45	14	microscopy	microscopy	NOUN
ct-9204	45	15	16	16	NUM
ct-9204	45	16	hours	hour	NOUN
ct-9204	45	17	after	after	ADP
ct-9204	45	18	incubation.60	incubation.60	PROPN
ct-9204	45	19	we	we	PRON
ct-9204	45	20	have	have	AUX
ct-9204	45	21	similarly	similarly	ADV
ct-9204	45	22	observed	observe	VERB
ct-9204	45	23	uptake	uptake	NOUN
ct-9204	45	24	of	of	ADP
ct-9204	45	25	ffev	ffev	NOUN
ct-9204	45	26	lipids	lipid	NOUN
ct-9204	45	27	and	and	CCONJ
ct-9204	45	28	proteins	protein	NOUN
ct-9204	45	29	only	only	ADV
ct-9204	45	30	in	in	ADP
ct-9204	45	31	cumulus	cumulus	ADJ
ct-9204	45	32	cells	cell	NOUN
ct-9204	45	33	of	of	ADP
ct-9204	45	34	feline	feline	ADJ
ct-9204	45	35	oocytes	oocyte	NOUN
ct-9204	45	36	after	after	ADP
ct-9204	45	37	18	18	NUM
ct-9204	45	38	hours	hour	NOUN
ct-9204	45	39	coincubation	coincubation	NOUN
ct-9204	45	40	(	(	PUNCT
ct-9204	45	41	manuscript	manuscript	NOUN
ct-9204	45	42	under	under	ADP
ct-9204	45	43	review	review	NOUN
ct-9204	45	44	)	)	PUNCT
ct-9204	45	45	.	.	PUNCT
ct-9204	46	1	however	however	ADV
ct-9204	46	2	,	,	PUNCT
ct-9204	46	3	in	in	ADP
ct-9204	46	4	ova	ova	NOUN
ct-9204	46	5	from	from	ADP
ct-9204	46	6	domestic	domestic	ADJ
ct-9204	46	7	dogs	dog	NOUN
ct-9204	46	8	,	,	PUNCT
ct-9204	46	9	oev	oev	NOUN
ct-9204	46	10	contents	content	NOUN
ct-9204	46	11	were	be	AUX
ct-9204	46	12	observed	observe	VERB
ct-9204	46	13	in	in	ADP
ct-9204	46	14	the	the	DET
ct-9204	46	15	oocyte	oocyte	NOUN
ct-9204	46	16	after	after	SCONJ
ct-9204	46	17	72	72	NUM
ct-9204	46	18	hours	hour	NOUN
ct-9204	46	19	incubation.75	incubation.75	ADJ
ct-9204	46	20	it	it	PRON
ct-9204	46	21	is	be	AUX
ct-9204	46	22	clear	clear	ADJ
ct-9204	46	23	,	,	PUNCT
ct-9204	46	24	therefore	therefore	ADV
ct-9204	46	25	,	,	PUNCT
ct-9204	46	26	that	that	SCONJ
ct-9204	46	27	an	an	DET
ct-9204	46	28	improved	improved	ADJ
ct-9204	46	29	understanding	understanding	NOUN
ct-9204	46	30	of	of	ADP
ct-9204	46	31	the	the	DET
ct-9204	46	32	kinetics	kinetic	NOUN
ct-9204	46	33	of	of	ADP
ct-9204	46	34	ev	ev	ADP
ct-9204	46	35	uptake	uptake	NOUN
ct-9204	46	36	into	into	ADP
ct-9204	46	37	oocytes	oocyte	NOUN
ct-9204	46	38	is	be	AUX
ct-9204	46	39	necessary	necessary	ADJ
ct-9204	46	40	to	to	PART
ct-9204	46	41	further	further	VERB
ct-9204	46	42	our	our	PRON
ct-9204	46	43	understanding	understanding	NOUN
ct-9204	46	44	of	of	ADP
ct-9204	46	45	their	their	PRON
ct-9204	46	46	functional	functional	ADJ
ct-9204	46	47	effects	effect	NOUN
ct-9204	46	48	and	and	CCONJ
ct-9204	46	49	any	any	DET
ct-9204	46	50	subsequent	subsequent	ADJ
ct-9204	46	51	reproductive	reproductive	ADJ
ct-9204	46	52	stage	stage	NOUN
ct-9204	46	53	-	-	PUNCT
ct-9204	46	54	specific	specific	ADJ
ct-9204	46	55	differences	difference	NOUN
ct-9204	46	56	.	.	PUNCT
ct-9204	47	1	potential	potential	NOUN
ct-9204	47	2	for	for	ADP
ct-9204	47	3	dramatic	dramatic	ADJ
ct-9204	47	4	differences	difference	NOUN
ct-9204	47	5	in	in	ADP
ct-9204	47	6	ev	ev	ADP
ct-9204	47	7	composition	composition	NOUN
ct-9204	47	8	by	by	ADP
ct-9204	47	9	reproductive	reproductive	ADJ
ct-9204	47	10	stage	stage	NOUN
ct-9204	47	11	/	/	SYM
ct-9204	47	12	status	status	NOUN
ct-9204	47	13	are	be	AUX
ct-9204	47	14	not	not	PART
ct-9204	47	15	limited	limit	VERB
ct-9204	47	16	to	to	ADP
ct-9204	47	17	female	female	ADJ
ct-9204	47	18	reproductive	reproductive	ADJ
ct-9204	47	19	tract	tract	NOUN
ct-9204	47	20	.	.	PUNCT
ct-9204	48	1	differences	difference	NOUN
ct-9204	48	2	in	in	ADP
ct-9204	48	3	protein	protein	NOUN
ct-9204	48	4	composition	composition	NOUN
ct-9204	48	5	of	of	ADP
ct-9204	48	6	seminal	seminal	ADJ
ct-9204	48	7	plasma	plasma	NOUN
ct-9204	48	8	during	during	ADP
ct-9204	48	9	breeding	breeding	NOUN
ct-9204	48	10	versus	versus	ADP
ct-9204	48	11	nonbreeding	nonbreede	VERB
ct-9204	48	12	seasons	season	NOUN
ct-9204	48	13	have	have	AUX
ct-9204	48	14	been	be	AUX
ct-9204	48	15	characterized	characterize	VERB
ct-9204	48	16	in	in	ADP
ct-9204	48	17	sheep76,77	sheep76,77	NOUN
ct-9204	48	18	and	and	CCONJ
ct-9204	48	19	goats.78,79	goats.78,79	NOUN
ct-9204	48	20	notably	notably	ADV
ct-9204	48	21	,	,	PUNCT
ct-9204	48	22	there	there	PRON
ct-9204	48	23	is	be	VERB
ct-9204	48	24	some	some	DET
ct-9204	48	25	evidence	evidence	NOUN
ct-9204	48	26	that	that	SCONJ
ct-9204	48	27	certain	certain	ADJ
ct-9204	48	28	protein	protein	NOUN
ct-9204	48	29	components	component	NOUN
ct-9204	48	30	of	of	ADP
ct-9204	48	31	breeding	breeding	NOUN
ct-9204	48	32	season	season	NOUN
ct-9204	48	33	(	(	PUNCT
ct-9204	48	34	autumn	autumn	NOUN
ct-9204	48	35	/	/	SYM
ct-9204	48	36	winter	winter	NOUN
ct-9204	48	37	)	)	PUNCT
ct-9204	48	38	seminal	seminal	ADJ
ct-9204	48	39	plasma	plasma	NOUN
ct-9204	48	40	improved	improve	VERB
ct-9204	48	41	motility	motility	NOUN
ct-9204	48	42	of	of	ADP
ct-9204	48	43	frozen	frozen	ADJ
ct-9204	48	44	-	-	PUNCT
ct-9204	48	45	thawed	thaw	VERB
ct-9204	48	46	ram	ram	NOUN
ct-9204	48	47	sperm	sperm	NOUN
ct-9204	48	48	;	;	PUNCT
ct-9204	48	49	however	however	ADV
ct-9204	48	50	,	,	PUNCT
ct-9204	48	51	this	this	DET
ct-9204	48	52	effect	effect	NOUN
ct-9204	48	53	was	be	AUX
ct-9204	48	54	not	not	PART
ct-9204	48	55	observed	observe	VERB
ct-9204	48	56	in	in	ADP
ct-9204	48	57	nonbreeding	nonbreede	VERB
ct-9204	48	58	season	season	NOUN
ct-9204	48	59	or	or	CCONJ
ct-9204	48	60	unsupplemented	unsupplemented	ADJ
ct-9204	48	61	sperm.80	sperm.80	NOUN
ct-9204	48	62	while	while	SCONJ
ct-9204	48	63	focus	focus	NOUN
ct-9204	48	64	of	of	ADP
ct-9204	48	65	these	these	DET
ct-9204	48	66	studies	study	NOUN
ct-9204	48	67	was	be	AUX
ct-9204	48	68	on	on	ADP
ct-9204	48	69	seminal	seminal	ADJ
ct-9204	48	70	plasma	plasma	NOUN
ct-9204	48	71	,	,	PUNCT
ct-9204	48	72	rather	rather	ADV
ct-9204	48	73	than	than	ADP
ct-9204	48	74	isolated	isolated	ADJ
ct-9204	48	75	evs	evs	NOUN
ct-9204	48	76	,	,	PUNCT
ct-9204	48	77	it	it	PRON
ct-9204	48	78	is	be	AUX
ct-9204	48	79	possible	possible	ADJ
ct-9204	48	80	that	that	SCONJ
ct-9204	48	81	some	some	DET
ct-9204	48	82	proteins	protein	NOUN
ct-9204	48	83	identified	identify	VERB
ct-9204	48	84	as	as	ADP
ct-9204	48	85	interacting	interact	VERB
ct-9204	48	86	with	with	ADP
ct-9204	48	87	sperm	sperm	NOUN
ct-9204	48	88	membranes	membrane	NOUN
ct-9204	48	89	are	be	AUX
ct-9204	48	90	derived	derive	VERB
ct-9204	48	91	from	from	ADP
ct-9204	48	92	evs	evs	PROPN
ct-9204	48	93	.	.	PUNCT
ct-9204	49	1	this	this	DET
ct-9204	49	2	assertion	assertion	NOUN
ct-9204	49	3	is	be	AUX
ct-9204	49	4	supported	support	VERB
ct-9204	49	5	by	by	ADP
ct-9204	49	6	the	the	DET
ct-9204	49	7	finding	finding	NOUN
ct-9204	49	8	that	that	SCONJ
ct-9204	49	9	there	there	PRON
ct-9204	49	10	were	be	VERB
ct-9204	49	11	no	no	DET
ct-9204	49	12	quantitative	quantitative	ADJ
ct-9204	49	13	differences	difference	NOUN
ct-9204	49	14	in	in	ADP
ct-9204	49	15	abundance	abundance	NOUN
ct-9204	49	16	of	of	ADP
ct-9204	49	17	most	most	ADJ
ct-9204	49	18	metabolic	metabolic	ADJ
ct-9204	49	19	enzymes	enzyme	NOUN
ct-9204	49	20	isolated	isolate	VERB
ct-9204	49	21	from	from	ADP
ct-9204	49	22	ram	ram	NOUN
ct-9204	49	23	seminal	seminal	ADJ
ct-9204	49	24	plasma	plasma	NOUN
ct-9204	49	25	extracellular	extracellular	ADJ
ct-9204	49	26	vesicles	vesicle	NOUN
ct-9204	49	27	versus	versus	ADP
ct-9204	49	28	whole	whole	ADJ
ct-9204	49	29	seminal	seminal	ADJ
ct-9204	49	30	plasma.81	plasma.81	NOUN
ct-9204	49	31	extracellular	extracellular	ADJ
ct-9204	49	32	vesicles	vesicle	NOUN
ct-9204	49	33	and	and	CCONJ
ct-9204	49	34	assisted	assist	VERB
ct-9204	49	35	reproductive	reproductive	ADJ
ct-9204	49	36	technologies	technology	NOUN
ct-9204	49	37	of	of	ADP
ct-9204	49	38	cryopreservation	cryopreservation	NOUN
ct-9204	49	39	potential	potential	NOUN
ct-9204	49	40	of	of	ADP
ct-9204	49	41	ev	ev	INTJ
ct-9204	49	42	for	for	ADP
ct-9204	49	43	assisted	assist	VERB
ct-9204	49	44	reproductive	reproductive	ADJ
ct-9204	49	45	technologies	technology	NOUN
ct-9204	49	46	,	,	PUNCT
ct-9204	49	47	especially	especially	ADV
ct-9204	49	48	in	in	ADP
ct-9204	49	49	vitro	vitro	X
ct-9204	49	50	embryo	embryo	NOUN
ct-9204	49	51	production	production	NOUN
ct-9204	49	52	,	,	PUNCT
ct-9204	49	53	has	have	AUX
ct-9204	49	54	been	be	AUX
ct-9204	49	55	elegantly	elegantly	ADV
ct-9204	49	56	reviewed	review	VERB
ct-9204	49	57	recently.28	recently.28	NOUN
ct-9204	49	58	here	here	ADV
ct-9204	49	59	,	,	PUNCT
ct-9204	49	60	we	we	PRON
ct-9204	49	61	focus	focus	VERB
ct-9204	49	62	on	on	ADP
ct-9204	49	63	new	new	ADJ
ct-9204	49	64	research	research	NOUN
ct-9204	49	65	into	into	ADP
ct-9204	49	66	potential	potential	ADJ
ct-9204	49	67	beneficial	beneficial	ADJ
ct-9204	49	68	effects	effect	NOUN
ct-9204	49	69	of	of	ADP
ct-9204	49	70	evs	evs	NOUN
ct-9204	49	71	in	in	ADP
ct-9204	49	72	cryopreservation	cryopreservation	NOUN
ct-9204	49	73	.	.	PUNCT
ct-9204	50	1	recent	recent	ADJ
ct-9204	50	2	reports	report	NOUN
ct-9204	50	3	of	of	ADP
ct-9204	50	4	ev	ev	ADP
ct-9204	50	5	supplementation	supplementation	NOUN
ct-9204	50	6	to	to	ADP
ct-9204	50	7	gamete	gamete	NOUN
ct-9204	50	8	and/or	and/or	CCONJ
ct-9204	50	9	embryo	embryo	NOUN
ct-9204	50	10	cryopreservation	cryopreservation	NOUN
ct-9204	50	11	yielded	yield	VERB
ct-9204	50	12	varying	vary	VERB
ct-9204	50	13	results	result	NOUN
ct-9204	50	14	.	.	PUNCT
ct-9204	51	1	significantly	significantly	ADV
ct-9204	51	2	improved	improve	VERB
ct-9204	51	3	survival	survival	NOUN
ct-9204	51	4	and	and	CCONJ
ct-9204	51	5	pregnancy	pregnancy	NOUN
ct-9204	51	6	success	success	NOUN
ct-9204	51	7	were	be	AUX
ct-9204	51	8	clinical	clinical	ADJ
ct-9204	51	9	theriogenology	theriogenology	NOUN
ct-9204	51	10	•	•	NOUN
ct-9204	51	11	volume	volume	NOUN
ct-9204	51	12	12	12	NUM
ct-9204	51	13	number	number	NOUN
ct-9204	51	14	2	2	NUM
ct-9204	51	15	•	•	NOUN
ct-9204	51	16	june	june	PROPN
ct-9204	51	17	2020	2020	NUM
ct-9204	51	18	93	93	NUM
ct-9204	51	19	observed	observe	VERB
ct-9204	51	20	with	with	ADP
ct-9204	51	21	cryopreserved	cryopreserve	VERB
ct-9204	51	22	and	and	CCONJ
ct-9204	51	23	thawed	thaw	VERB
ct-9204	51	24	in	in	ADP
ct-9204	51	25	vitro	vitro	X
ct-9204	51	26	-	-	PUNCT
ct-9204	51	27	derived	derive	VERB
ct-9204	51	28	bovine	bovine	NOUN
ct-9204	51	29	embryos	embryo	NOUN
ct-9204	51	30	cultured	culture	VERB
ct-9204	51	31	in	in	ADP
ct-9204	51	32	amniotic	amniotic	ADJ
ct-9204	51	33	mv	mv	PROPN
ct-9204	51	34	(	(	PUNCT
ct-9204	51	35	from	from	ADP
ct-9204	51	36	days	day	NOUN
ct-9204	51	37	5	5	NUM
ct-9204	51	38	7	7	NUM
ct-9204	51	39	following	follow	VERB
ct-9204	51	40	ivf	ivf	NOUN
ct-9204	51	41	)	)	PUNCT
ct-9204	51	42	,	,	PUNCT
ct-9204	51	43	compared	compare	VERB
ct-9204	51	44	to	to	ADP
ct-9204	51	45	unsupplemented	unsupplemented	ADJ
ct-9204	51	46	controls.82	controls.82	NOUN
ct-9204	51	47	zygotes	zygote	NOUN
ct-9204	51	48	coincubated	coincubate	VERB
ct-9204	51	49	with	with	ADP
ct-9204	51	50	oevs	oevs	NOUN
ct-9204	51	51	from	from	ADP
ct-9204	51	52	either	either	CCONJ
ct-9204	51	53	the	the	DET
ct-9204	51	54	isthmus	isthmus	NOUN
ct-9204	51	55	or	or	CCONJ
ct-9204	51	56	ampulla	ampulla	NOUN
ct-9204	51	57	of	of	ADP
ct-9204	51	58	the	the	DET
ct-9204	51	59	oviduct	oviduct	NOUN
ct-9204	51	60	were	be	AUX
ct-9204	51	61	compared	compare	VERB
ct-9204	51	62	to	to	ADP
ct-9204	51	63	unsupplemented	unsupplemented	ADJ
ct-9204	51	64	or	or	CCONJ
ct-9204	51	65	fetal	fetal	ADJ
ct-9204	51	66	calf	calf	NOUN
ct-9204	51	67	serum	serum	NOUN
ct-9204	51	68	supplemented	supplement	VERB
ct-9204	51	69	controls.83	controls.83	ADJ
ct-9204	51	70	blastocysts	blastocyst	NOUN
ct-9204	51	71	developing	develop	VERB
ct-9204	51	72	from	from	ADP
ct-9204	51	73	isthmic	isthmic	ADJ
ct-9204	51	74	oev	oev	NOUN
ct-9204	51	75	-	-	PUNCT
ct-9204	51	76	supplemented	supplement	VERB
ct-9204	51	77	cultures	culture	NOUN
ct-9204	51	78	displayed	display	VERB
ct-9204	51	79	improved	improve	VERB
ct-9204	51	80	post	post	ADJ
ct-9204	51	81	-	-	ADJ
ct-9204	51	82	thaw	thaw	ADJ
ct-9204	51	83	survival	survival	NOUN
ct-9204	51	84	rate	rate	NOUN
ct-9204	51	85	(	(	PUNCT
ct-9204	51	86	determined	determine	VERB
ct-9204	51	87	via	via	ADP
ct-9204	51	88	reexpansion	reexpansion	NOUN
ct-9204	51	89	of	of	ADP
ct-9204	51	90	blastocoel	blastocoel	NOUN
ct-9204	51	91	cavity	cavity	NOUN
ct-9204	51	92	)	)	PUNCT
ct-9204	51	93	compared	compare	VERB
ct-9204	51	94	to	to	ADP
ct-9204	51	95	control	control	VERB
ct-9204	51	96	and	and	CCONJ
ct-9204	51	97	fbs	fb	VERB
ct-9204	51	98	supplemented	supplement	VERB
ct-9204	51	99	groups	group	NOUN
ct-9204	51	100	.	.	PUNCT
ct-9204	52	1	conversely	conversely	ADV
ct-9204	52	2	,	,	PUNCT
ct-9204	52	3	bovine	bovine	ADJ
ct-9204	52	4	embryos	embryo	NOUN
ct-9204	52	5	cultured	culture	VERB
ct-9204	52	6	with	with	ADP
ct-9204	52	7	varying	vary	VERB
ct-9204	52	8	concentrations	concentration	NOUN
ct-9204	52	9	(	(	PUNCT
ct-9204	52	10	based	base	VERB
ct-9204	52	11	on	on	ADP
ct-9204	52	12	protein	protein	NOUN
ct-9204	52	13	content	content	NOUN
ct-9204	52	14	)	)	PUNCT
ct-9204	52	15	of	of	ADP
ct-9204	52	16	postovulatory	postovulatory	NOUN
ct-9204	52	17	oevs	oevs	PROPN
ct-9204	52	18	had	have	AUX
ct-9204	52	19	improved	improve	VERB
ct-9204	52	20	day	day	NOUN
ct-9204	52	21	7	7	NUM
ct-9204	52	22	blastocyst	blastocyst	NOUN
ct-9204	52	23	rates	rate	NOUN
ct-9204	52	24	,	,	PUNCT
ct-9204	52	25	but	but	CCONJ
ct-9204	52	26	supplementation	supplementation	NOUN
ct-9204	52	27	had	have	VERB
ct-9204	52	28	no	no	DET
ct-9204	52	29	effect	effect	NOUN
ct-9204	52	30	on	on	ADP
ct-9204	52	31	cryotolerance	cryotolerance	NOUN
ct-9204	52	32	of	of	ADP
ct-9204	52	33	blastocysts	blastocyst	NOUN
ct-9204	52	34	,	,	PUNCT
ct-9204	52	35	as	as	SCONJ
ct-9204	52	36	evaluated	evaluate	VERB
ct-9204	52	37	by	by	ADP
ct-9204	52	38	hatching	hatch	VERB
ct-9204	52	39	rates.84	rates.84	NOUN
ct-9204	52	40	further	far	ADV
ct-9204	52	41	,	,	PUNCT
ct-9204	52	42	postthaw	postthaw	NOUN
ct-9204	52	43	survival	survival	NOUN
ct-9204	52	44	of	of	ADP
ct-9204	52	45	bovine	bovine	NOUN
ct-9204	52	46	blastocysts	blastocyst	NOUN
ct-9204	52	47	sequentially	sequentially	ADV
ct-9204	52	48	cultured	cultured	ADJ
ct-9204	52	49	in	in	ADP
ct-9204	52	50	oevs	oevs	ADJ
ct-9204	52	51	and	and	CCONJ
ct-9204	52	52	uterus	uterus	NOUN
ct-9204	52	53	-	-	PUNCT
ct-9204	52	54	derived	derive	VERB
ct-9204	52	55	evs	evs	NOUN
ct-9204	52	56	was	be	AUX
ct-9204	52	57	not	not	PART
ct-9204	52	58	significantly	significantly	ADV
ct-9204	52	59	improved	improve	VERB
ct-9204	52	60	compared	compare	VERB
ct-9204	52	61	to	to	PART
ct-9204	52	62	controls.85	controls.85	VERB
ct-9204	52	63	as	as	SCONJ
ct-9204	52	64	each	each	DET
ct-9204	52	65	study	study	NOUN
ct-9204	52	66	utilized	utilize	VERB
ct-9204	52	67	different	different	ADV
ct-9204	52	68	ev	ev	ADP
ct-9204	52	69	sources	source	NOUN
ct-9204	52	70	(	(	PUNCT
ct-9204	52	71	amniotic	amniotic	ADJ
ct-9204	52	72	,	,	PUNCT
ct-9204	52	73	oviductal	oviductal	ADJ
ct-9204	52	74	and	and	CCONJ
ct-9204	52	75	uterine	uterine	ADJ
ct-9204	52	76	fluid	fluid	NOUN
ct-9204	52	77	alone	alone	ADJ
ct-9204	52	78	or	or	CCONJ
ct-9204	52	79	in	in	ADP
ct-9204	52	80	combination	combination	NOUN
ct-9204	52	81	)	)	PUNCT
ct-9204	52	82	,	,	PUNCT
ct-9204	52	83	isolation	isolation	NOUN
ct-9204	52	84	methods	method	NOUN
ct-9204	52	85	,	,	PUNCT
ct-9204	52	86	and	and	CCONJ
ct-9204	52	87	concentrations	concentration	NOUN
ct-9204	52	88	,	,	PUNCT
ct-9204	52	89	as	as	ADV
ct-9204	52	90	well	well	ADV
ct-9204	52	91	as	as	ADP
ct-9204	52	92	coculture	coculture	NOUN
ct-9204	52	93	timings	timing	NOUN
ct-9204	52	94	and	and	CCONJ
ct-9204	52	95	metrics	metric	NOUN
ct-9204	52	96	of	of	ADP
ct-9204	52	97	success	success	NOUN
ct-9204	52	98	,	,	PUNCT
ct-9204	52	99	the	the	DET
ct-9204	52	100	full	full	ADJ
ct-9204	52	101	influence	influence	NOUN
ct-9204	52	102	of	of	ADP
ct-9204	52	103	reproductive	reproductive	ADJ
ct-9204	52	104	evs	evs	NOUN
ct-9204	52	105	on	on	ADP
ct-9204	52	106	bovine	bovine	ADJ
ct-9204	52	107	embryo	embryo	NOUN
ct-9204	52	108	cryopreservation	cryopreservation	NOUN
ct-9204	52	109	is	be	AUX
ct-9204	52	110	not	not	PART
ct-9204	52	111	yet	yet	ADV
ct-9204	52	112	clear	clear	ADJ
ct-9204	52	113	.	.	PUNCT
ct-9204	53	1	in	in	ADP
ct-9204	53	2	our	our	PRON
ct-9204	53	3	laboratory	laboratory	NOUN
ct-9204	53	4	,	,	PUNCT
ct-9204	53	5	ffev	ffev	NOUN
ct-9204	53	6	supplementation	supplementation	NOUN
ct-9204	53	7	during	during	ADP
ct-9204	53	8	cryopreservation	cryopreservation	NOUN
ct-9204	53	9	and	and	CCONJ
ct-9204	53	10	thawing	thawing	NOUN
ct-9204	53	11	of	of	ADP
ct-9204	53	12	domestic	domestic	ADJ
ct-9204	53	13	cat	cat	NOUN
ct-9204	53	14	oocytes	oocyte	NOUN
ct-9204	53	15	did	do	AUX
ct-9204	53	16	not	not	PART
ct-9204	53	17	improve	improve	VERB
ct-9204	53	18	survival	survival	NOUN
ct-9204	53	19	based	base	VERB
ct-9204	53	20	on	on	ADP
ct-9204	53	21	morphology	morphology	NOUN
ct-9204	53	22	,	,	PUNCT
ct-9204	53	23	but	but	CCONJ
ct-9204	53	24	did	do	AUX
ct-9204	53	25	enhance	enhance	VERB
ct-9204	53	26	ability	ability	NOUN
ct-9204	53	27	of	of	ADP
ct-9204	53	28	frozen	frozen	ADJ
ct-9204	53	29	and	and	CCONJ
ct-9204	53	30	thawed	thawed	ADJ
ct-9204	53	31	oocytes	oocyte	NOUN
ct-9204	53	32	to	to	PART
ct-9204	53	33	resume	resume	VERB
ct-9204	53	34	meiosis	meiosis	NOUN
ct-9204	53	35	in	in	ADP
ct-9204	53	36	vitro	vitro	X
ct-9204	53	37	(	(	PUNCT
ct-9204	53	38	manuscript	manuscript	NOUN
ct-9204	53	39	under	under	ADP
ct-9204	53	40	revision	revision	NOUN
ct-9204	53	41	)	)	PUNCT
ct-9204	53	42	.	.	PUNCT
ct-9204	54	1	still	still	ADV
ct-9204	54	2	,	,	PUNCT
ct-9204	54	3	proteomic	proteomic	ADJ
ct-9204	54	4	analyses	analysis	NOUN
ct-9204	54	5	of	of	ADP
ct-9204	54	6	cat	cat	NOUN
ct-9204	54	7	ffevs	ffevs	NOUN
ct-9204	54	8	identified	identify	VERB
ct-9204	54	9	proteins	protein	NOUN
ct-9204	54	10	with	with	ADP
ct-9204	54	11	known	know	VERB
ct-9204	54	12	cryomodulating	cryomodulating	NOUN
ct-9204	54	13	effects	effect	NOUN
ct-9204	54	14	,	,	PUNCT
ct-9204	54	15	including	include	VERB
ct-9204	54	16	heat	heat	NOUN
ct-9204	54	17	shock	shock	NOUN
ct-9204	54	18	proteins	protein	NOUN
ct-9204	54	19	(	(	PUNCT
ct-9204	54	20	hsp	hsp	NOUN
ct-9204	54	21	)	)	PUNCT
ct-9204	54	22	,	,	PUNCT
ct-9204	54	23	cytoskeletal	cytoskeletal	ADJ
ct-9204	54	24	elements	element	NOUN
ct-9204	54	25	,	,	PUNCT
ct-9204	54	26	and	and	CCONJ
ct-9204	54	27	oxidoreductases	oxidoreductase	NOUN
ct-9204	54	28	.	.	PUNCT
ct-9204	55	1	for	for	ADP
ct-9204	55	2	example	example	NOUN
ct-9204	55	3	,	,	PUNCT
ct-9204	55	4	treatment	treatment	NOUN
ct-9204	55	5	of	of	ADP
ct-9204	55	6	oocytes	oocyte	NOUN
ct-9204	55	7	with	with	ADP
ct-9204	55	8	cytoskeleton	cytoskeleton	NOUN
ct-9204	55	9	stabilizing	stabilize	VERB
ct-9204	55	10	agents	agent	NOUN
ct-9204	55	11	improved	improve	VERB
ct-9204	55	12	cryopreservation	cryopreservation	NOUN
ct-9204	55	13	success	success	NOUN
ct-9204	55	14	in	in	ADP
ct-9204	55	15	mice86	mice86	PROPN
ct-9204	55	16	and	and	CCONJ
ct-9204	55	17	cows.87	cows.87	VERB
ct-9204	55	18	significant	significant	ADJ
ct-9204	55	19	loss	loss	NOUN
ct-9204	55	20	of	of	ADP
ct-9204	55	21	chaperone	chaperone	NOUN
ct-9204	55	22	proteins	protein	NOUN
ct-9204	55	23	like	like	ADP
ct-9204	55	24	hsps	hsp	NOUN
ct-9204	55	25	and	and	CCONJ
ct-9204	55	26	oxidoreductases	oxidoreductase	NOUN
ct-9204	55	27	have	have	AUX
ct-9204	55	28	been	be	AUX
ct-9204	55	29	observed	observe	VERB
ct-9204	55	30	following	follow	VERB
ct-9204	55	31	sperm	sperm	NOUN
ct-9204	55	32	cryopreservation	cryopreservation	NOUN
ct-9204	55	33	in	in	ADP
ct-9204	55	34	sheep88	sheep88	NOUN
ct-9204	55	35	and	and	CCONJ
ct-9204	55	36	carp,89	carp,89	ADJ
ct-9204	55	37	respectively	respectively	ADV
ct-9204	55	38	.	.	PUNCT
ct-9204	56	1	transfer	transfer	NOUN
ct-9204	56	2	of	of	ADP
ct-9204	56	3	these	these	PRON
ct-9204	56	4	and	and	CCONJ
ct-9204	56	5	other	other	ADJ
ct-9204	56	6	potentially	potentially	ADV
ct-9204	56	7	cryoprotective	cryoprotective	ADJ
ct-9204	56	8	proteins	protein	NOUN
ct-9204	56	9	may	may	AUX
ct-9204	56	10	have	have	AUX
ct-9204	56	11	supported	support	VERB
ct-9204	56	12	postthaw	postthaw	NOUN
ct-9204	56	13	recovery	recovery	NOUN
ct-9204	56	14	of	of	ADP
ct-9204	56	15	gametes	gamete	NOUN
ct-9204	56	16	;	;	PUNCT
ct-9204	56	17	however	however	ADV
ct-9204	56	18	,	,	PUNCT
ct-9204	56	19	much	much	ADV
ct-9204	56	20	more	more	ADJ
ct-9204	56	21	work	work	NOUN
ct-9204	56	22	is	be	AUX
ct-9204	56	23	necessary	necessary	ADJ
ct-9204	56	24	in	in	ADP
ct-9204	56	25	this	this	DET
ct-9204	56	26	area	area	NOUN
ct-9204	56	27	as	as	ADV
ct-9204	56	28	well	well	ADV
ct-9204	56	29	.	.	PUNCT
ct-9204	57	1	for	for	ADP
ct-9204	57	2	sperm	sperm	NOUN
ct-9204	57	3	,	,	PUNCT
ct-9204	57	4	the	the	DET
ct-9204	57	5	addition	addition	NOUN
ct-9204	57	6	of	of	ADP
ct-9204	57	7	bovine	bovine	ADJ
ct-9204	57	8	oevs	oevs	ADJ
ct-9204	57	9	postthaw	postthaw	NOUN
ct-9204	57	10	maintains	maintain	VERB
ct-9204	57	11	viability	viability	NOUN
ct-9204	57	12	while	while	SCONJ
ct-9204	57	13	supporting	support	VERB
ct-9204	57	14	capacitation	capacitation	NOUN
ct-9204	57	15	during	during	ADP
ct-9204	57	16	incubation	incubation	NOUN
ct-9204	57	17	,	,	PUNCT
ct-9204	57	18	compared	compare	VERB
ct-9204	57	19	to	to	ADP
ct-9204	57	20	sperm	sperm	NOUN
ct-9204	57	21	incubated	incubate	VERB
ct-9204	57	22	under	under	ADP
ct-9204	57	23	capacitating	capacitate	VERB
ct-9204	57	24	conditions	condition	NOUN
ct-9204	57	25	in	in	ADP
ct-9204	57	26	oev	oev	NOUN
ct-9204	57	27	absence.62	absence.62	NOUN
ct-9204	57	28	cryopreservation	cryopreservation	NOUN
ct-9204	57	29	significantly	significantly	ADV
ct-9204	57	30	alters	alter	VERB
ct-9204	57	31	sperm	sperm	NOUN
ct-9204	57	32	membrane	membrane	NOUN
ct-9204	57	33	’s	’s	PART
ct-9204	57	34	lipid	lipid	NOUN
ct-9204	57	35	compositions	composition	NOUN
ct-9204	57	36	(	(	PUNCT
ct-9204	57	37	reviewed90	reviewed90	NOUN
ct-9204	57	38	)	)	PUNCT
ct-9204	57	39	,	,	PUNCT
ct-9204	57	40	including	include	VERB
ct-9204	57	41	reducing	reduce	VERB
ct-9204	57	42	sterols	sterol	NOUN
ct-9204	57	43	,	,	PUNCT
ct-9204	57	44	phosphatidyl	phosphatidyl	NOUN
ct-9204	57	45	choline	choline	NOUN
ct-9204	57	46	,	,	PUNCT
ct-9204	57	47	and	and	CCONJ
ct-9204	57	48	unsaturated	unsaturated	ADJ
ct-9204	57	49	fatty	fatty	NOUN
ct-9204	57	50	acids	acid	NOUN
ct-9204	57	51	in	in	ADP
ct-9204	57	52	caprine	caprine	NOUN
ct-9204	57	53	sperm	sperm	NOUN
ct-9204	57	54	membranes.91	membranes.91	NOUN
ct-9204	57	55	as	as	SCONJ
ct-9204	57	56	previously	previously	ADV
ct-9204	57	57	mentioned	mention	VERB
ct-9204	57	58	,	,	PUNCT
ct-9204	57	59	evs	evs	VERB
ct-9204	57	60	contain	contain	VERB
ct-9204	57	61	high	high	ADJ
ct-9204	57	62	concentrations	concentration	NOUN
ct-9204	57	63	of	of	ADP
ct-9204	57	64	lipids	lipid	NOUN
ct-9204	57	65	and	and	CCONJ
ct-9204	57	66	proteins	protein	NOUN
ct-9204	57	67	associated	associate	VERB
ct-9204	57	68	with	with	ADP
ct-9204	57	69	lipid	lipid	NOUN
ct-9204	57	70	-	-	PUNCT
ct-9204	57	71	rafts	raft	NOUN
ct-9204	57	72	,	,	PUNCT
ct-9204	57	73	which	which	PRON
ct-9204	57	74	likely	likely	ADV
ct-9204	57	75	supports	support	VERB
ct-9204	57	76	their	their	PRON
ct-9204	57	77	membrane	membrane	NOUN
ct-9204	57	78	fusion	fusion	NOUN
ct-9204	57	79	and	and	CCONJ
ct-9204	57	80	stability	stability	NOUN
ct-9204	57	81	in	in	ADP
ct-9204	57	82	vitro,92	vitro,92	NOUN
ct-9204	57	83	but	but	CCONJ
ct-9204	57	84	also	also	ADV
ct-9204	57	85	could	could	AUX
ct-9204	57	86	support	support	VERB
ct-9204	57	87	recovery	recovery	NOUN
ct-9204	57	88	of	of	ADP
ct-9204	57	89	cryodamaged	cryodamage	VERB
ct-9204	57	90	sperm	sperm	NOUN
ct-9204	57	91	membranes	membrane	NOUN
ct-9204	57	92	upon	upon	SCONJ
ct-9204	57	93	fusion	fusion	NOUN
ct-9204	57	94	.	.	PUNCT
ct-9204	58	1	lipid	lipid	NOUN
ct-9204	58	2	component	component	NOUN
ct-9204	58	3	is	be	AUX
ct-9204	58	4	part	part	NOUN
ct-9204	58	5	of	of	ADP
ct-9204	58	6	rationale	rationale	NOUN
ct-9204	58	7	behind	behind	ADP
ct-9204	58	8	addition	addition	NOUN
ct-9204	58	9	of	of	ADP
ct-9204	58	10	egg	egg	NOUN
ct-9204	58	11	yolk	yolk	NOUN
ct-9204	58	12	to	to	ADP
ct-9204	58	13	sperm	sperm	NOUN
ct-9204	58	14	cryopreservation	cryopreservation	NOUN
ct-9204	58	15	media.93	media.93	PROPN
ct-9204	58	16	more	more	ADV
ct-9204	58	17	recently	recently	ADV
ct-9204	58	18	,	,	PUNCT
ct-9204	58	19	a	a	DET
ct-9204	58	20	liposome	liposome	NOUN
ct-9204	58	21	-	-	PUNCT
ct-9204	58	22	based	base	VERB
ct-9204	58	23	medium	medium	NOUN
ct-9204	58	24	(	(	PUNCT
ct-9204	58	25	optixcell	optixcell	INTJ
ct-9204	58	26	)	)	PUNCT
ct-9204	58	27	was	be	AUX
ct-9204	58	28	evaluated	evaluate	VERB
ct-9204	58	29	for	for	ADP
ct-9204	58	30	cryopreservation	cryopreservation	NOUN
ct-9204	58	31	of	of	ADP
ct-9204	58	32	ram,94	ram,94	ADJ
ct-9204	58	33	buffalo,95	buffalo,95	NUM
ct-9204	58	34	bull,96,97	bull,96,97	NOUN
ct-9204	58	35	deer,98	deer,98	NOUN
ct-9204	58	36	and	and	CCONJ
ct-9204	58	37	rhino99	rhino99	NOUN
ct-9204	58	38	sperm	sperm	NOUN
ct-9204	58	39	,	,	PUNCT
ct-9204	58	40	with	with	ADP
ct-9204	58	41	promising	promising	ADJ
ct-9204	58	42	results	result	NOUN
ct-9204	58	43	overall	overall	ADV
ct-9204	58	44	,	,	PUNCT
ct-9204	58	45	even	even	ADV
ct-9204	58	46	when	when	SCONJ
ct-9204	58	47	compared	compare	VERB
ct-9204	58	48	to	to	ADP
ct-9204	58	49	egg	egg	NOUN
ct-9204	58	50	yolk	yolk	NOUN
ct-9204	58	51	,	,	PUNCT
ct-9204	58	52	the	the	DET
ct-9204	58	53	current	current	ADJ
ct-9204	58	54	‘	'	PUNCT
ct-9204	58	55	gold	gold	NOUN
ct-9204	58	56	-	-	PUNCT
ct-9204	58	57	standard	standard	NOUN
ct-9204	58	58	’	'	PUNCT
ct-9204	58	59	.	.	PUNCT
ct-9204	59	1	similar	similar	ADJ
ct-9204	59	2	to	to	AUX
ct-9204	59	3	evs	evs	VERB
ct-9204	59	4	,	,	PUNCT
ct-9204	59	5	liposomes	liposome	NOUN
ct-9204	59	6	are	be	AUX
ct-9204	59	7	phospholipid	phospholipid	NOUN
ct-9204	59	8	membrane	membrane	NOUN
ct-9204	59	9	vesicles	vesicle	NOUN
ct-9204	59	10	,	,	PUNCT
ct-9204	59	11	though	though	SCONJ
ct-9204	59	12	they	they	PRON
ct-9204	59	13	lack	lack	VERB
ct-9204	59	14	protein	protein	NOUN
ct-9204	59	15	cargo	cargo	NOUN
ct-9204	59	16	.	.	PUNCT
ct-9204	60	1	it	it	PRON
ct-9204	60	2	is	be	AUX
ct-9204	60	3	feasible	feasible	ADJ
ct-9204	60	4	that	that	SCONJ
ct-9204	60	5	combining	combine	VERB
ct-9204	60	6	our	our	PRON
ct-9204	60	7	understanding	understand	VERB
ct-9204	60	8	proteins	protein	NOUN
ct-9204	60	9	present	present	ADJ
ct-9204	60	10	in	in	ADP
ct-9204	60	11	ev	ev	ADJ
ct-9204	60	12	membranes	membrane	NOUN
ct-9204	60	13	,	,	PUNCT
ct-9204	60	14	particularly	particularly	ADV
ct-9204	60	15	those	those	PRON
ct-9204	60	16	likely	likely	ADJ
ct-9204	60	17	to	to	PART
ct-9204	60	18	target	target	VERB
ct-9204	60	19	gametes	gamete	NOUN
ct-9204	60	20	and	and	CCONJ
ct-9204	60	21	promote	promote	VERB
ct-9204	60	22	uptake	uptake	ADJ
ct-9204	60	23	,	,	PUNCT
ct-9204	60	24	we	we	PRON
ct-9204	60	25	may	may	AUX
ct-9204	60	26	be	be	AUX
ct-9204	60	27	able	able	ADJ
ct-9204	60	28	to	to	PART
ct-9204	60	29	engineer	engineer	VERB
ct-9204	60	30	vesicles	vesicle	NOUN
ct-9204	60	31	with	with	ADP
ct-9204	60	32	specific	specific	ADJ
ct-9204	60	33	lipid	lipid	NOUN
ct-9204	60	34	and/or	and/or	CCONJ
ct-9204	60	35	protein	protein	NOUN
ct-9204	60	36	compositions	composition	NOUN
ct-9204	60	37	to	to	PART
ct-9204	60	38	support	support	VERB
ct-9204	60	39	cryosurvival	cryosurvival	NOUN
ct-9204	60	40	while	while	SCONJ
ct-9204	60	41	maintaining	maintain	VERB
ct-9204	60	42	high	high	ADJ
ct-9204	60	43	affinity	affinity	NOUN
ct-9204	60	44	for	for	ADP
ct-9204	60	45	gametes	gamete	NOUN
ct-9204	60	46	.	.	PUNCT
ct-9204	61	1	future	future	ADJ
ct-9204	61	2	extracellular	extracellular	ADJ
ct-9204	61	3	vesicles	vesicle	NOUN
ct-9204	61	4	production	production	NOUN
ct-9204	61	5	for	for	ADP
ct-9204	61	6	therapeutics	therapeutic	NOUN
ct-9204	61	7	applications	application	NOUN
ct-9204	61	8	of	of	ADP
ct-9204	61	9	evs	evs	NOUN
ct-9204	61	10	to	to	ADP
ct-9204	61	11	assisted	assisted	ADJ
ct-9204	61	12	reproduction	reproduction	NOUN
ct-9204	61	13	is	be	AUX
ct-9204	61	14	faced	face	VERB
ct-9204	61	15	with	with	ADP
ct-9204	61	16	several	several	ADJ
ct-9204	61	17	challenges	challenge	NOUN
ct-9204	61	18	,	,	PUNCT
ct-9204	61	19	including	include	VERB
ct-9204	61	20	the	the	DET
ct-9204	61	21	aforementioned	aforementioned	ADJ
ct-9204	61	22	need	need	NOUN
ct-9204	61	23	to	to	PART
ct-9204	61	24	improve	improve	VERB
ct-9204	61	25	our	our	PRON
ct-9204	61	26	ability	ability	NOUN
ct-9204	61	27	to	to	PART
ct-9204	61	28	isolate	isolate	VERB
ct-9204	61	29	,	,	PUNCT
ct-9204	61	30	purify	purify	VERB
ct-9204	61	31	and	and	CCONJ
ct-9204	61	32	characterize	characterize	VERB
ct-9204	61	33	evs	evs	NOUN
ct-9204	61	34	.	.	PUNCT
ct-9204	62	1	however	however	ADV
ct-9204	62	2	,	,	PUNCT
ct-9204	62	3	even	even	ADV
ct-9204	62	4	once	once	SCONJ
ct-9204	62	5	we	we	PRON
ct-9204	62	6	have	have	VERB
ct-9204	62	7	a	a	DET
ct-9204	62	8	better	well	ADJ
ct-9204	62	9	understanding	understanding	NOUN
ct-9204	62	10	of	of	ADP
ct-9204	62	11	evs	evs	NOUN
ct-9204	62	12	and	and	CCONJ
ct-9204	62	13	optimal	optimal	ADJ
ct-9204	62	14	(	(	PUNCT
ct-9204	62	15	and	and	CCONJ
ct-9204	62	16	standardized	standardized	ADJ
ct-9204	62	17	)	)	PUNCT
ct-9204	62	18	methods	method	NOUN
ct-9204	62	19	to	to	PART
ct-9204	62	20	purify	purify	VERB
ct-9204	62	21	populations	population	NOUN
ct-9204	62	22	of	of	ADP
ct-9204	62	23	interest	interest	NOUN
ct-9204	62	24	,	,	PUNCT
ct-9204	62	25	evs	evs	VERB
ct-9204	62	26	with	with	ADP
ct-9204	62	27	consistent	consistent	ADJ
ct-9204	62	28	characteristics	characteristic	NOUN
ct-9204	62	29	with	with	ADP
ct-9204	62	30	low	low	ADJ
ct-9204	62	31	variability	variability	NOUN
ct-9204	62	32	must	must	AUX
ct-9204	62	33	be	be	AUX
ct-9204	62	34	producible	producible	ADJ
ct-9204	62	35	in	in	ADP
ct-9204	62	36	large	large	ADJ
ct-9204	62	37	quantities	quantity	NOUN
ct-9204	62	38	.	.	PUNCT
ct-9204	63	1	this	this	PRON
ct-9204	63	2	is	be	AUX
ct-9204	63	3	not	not	PART
ct-9204	63	4	feasible	feasible	ADJ
ct-9204	63	5	with	with	ADP
ct-9204	63	6	in	in	ADP
ct-9204	63	7	vivo	vivo	NOUN
ct-9204	63	8	sources	source	NOUN
ct-9204	63	9	.	.	PUNCT
ct-9204	64	1	beyond	beyond	ADP
ct-9204	64	2	inherent	inherent	ADJ
ct-9204	64	3	variability	variability	NOUN
ct-9204	64	4	,	,	PUNCT
ct-9204	64	5	flushing	flush	VERB
ct-9204	64	6	both	both	DET
ct-9204	64	7	oviducts	oviduct	NOUN
ct-9204	64	8	(	(	PUNCT
ct-9204	64	9	figure	figure	NOUN
ct-9204	64	10	3a	3a	NUM
ct-9204	64	11	)	)	PUNCT
ct-9204	64	12	of	of	ADP
ct-9204	64	13	a	a	DET
ct-9204	64	14	single	single	ADJ
ct-9204	64	15	individual	individual	NOUN
ct-9204	64	16	with	with	ADP
ct-9204	64	17	the	the	DET
ct-9204	64	18	aforementioned	aforementioned	ADJ
ct-9204	64	19	total	total	NOUN
ct-9204	64	20	exosome	exosome	PROPN
ct-9204	64	21	isolation	isolation	NOUN
ct-9204	64	22	kit	kit	NOUN
ct-9204	64	23	,	,	PUNCT
ct-9204	64	24	we	we	PRON
ct-9204	64	25	isolate	isolate	VERB
ct-9204	64	26	on	on	ADP
ct-9204	64	27	average	average	ADJ
ct-9204	64	28	3.1	3.1	NUM
ct-9204	64	29	x	x	SYM
ct-9204	64	30	1010	1010	NUM
ct-9204	64	31	and	and	CCONJ
ct-9204	64	32	4.5	4.5	NUM
ct-9204	64	33	x	x	SYM
ct-9204	64	34	1010	1010	NUM
ct-9204	64	35	ev	ev	PART
ct-9204	64	36	/	/	SYM
ct-9204	64	37	ml	ml	PROPN
ct-9204	64	38	(	(	PUNCT
ct-9204	64	39	in	in	ADP
ct-9204	64	40	1	1	NUM
ct-9204	64	41	ml	ml	NOUN
ct-9204	64	42	)	)	PUNCT
ct-9204	64	43	from	from	ADP
ct-9204	64	44	domestic	domestic	ADJ
ct-9204	64	45	cats	cat	NOUN
ct-9204	64	46	and	and	CCONJ
ct-9204	64	47	dogs	dog	NOUN
ct-9204	64	48	,	,	PUNCT
ct-9204	64	49	respectively	respectively	ADV
ct-9204	64	50	.	.	PUNCT
ct-9204	65	1	in	in	ADP
ct-9204	65	2	contrast	contrast	NOUN
ct-9204	65	3	,	,	PUNCT
ct-9204	65	4	for	for	ADP
ct-9204	65	5	our	our	PRON
ct-9204	65	6	experimental	experimental	ADJ
ct-9204	65	7	purposes	purpose	NOUN
ct-9204	65	8	,	,	PUNCT
ct-9204	65	9	we	we	PRON
ct-9204	65	10	typically	typically	ADV
ct-9204	65	11	utilize	utilize	VERB
ct-9204	65	12	~	~	PUNCT
ct-9204	65	13	3	3	NUM
ct-9204	65	14	x	x	SYM
ct-9204	65	15	107	107	NUM
ct-9204	65	16	evs	evs	NOUN
ct-9204	65	17	/	/	SYM
ct-9204	65	18	ml	ml	NOUN
ct-9204	65	19	.	.	PUNCT
ct-9204	66	1	though	though	SCONJ
ct-9204	66	2	this	this	PRON
ct-9204	66	3	is	be	AUX
ct-9204	66	4	sufficient	sufficient	ADJ
ct-9204	66	5	in	in	ADP
ct-9204	66	6	a	a	DET
ct-9204	66	7	laboratory	laboratory	NOUN
ct-9204	66	8	setting	setting	NOUN
ct-9204	66	9	,	,	PUNCT
ct-9204	66	10	high	high	ADJ
ct-9204	66	11	throughput	throughput	NOUN
ct-9204	66	12	production	production	NOUN
ct-9204	66	13	of	of	ADP
ct-9204	66	14	evs	evs	PROPN
ct-9204	66	15	is	be	AUX
ct-9204	66	16	necessary	necessary	ADJ
ct-9204	66	17	for	for	ADP
ct-9204	66	18	clinical	clinical	ADJ
ct-9204	66	19	applications	application	NOUN
ct-9204	66	20	.	.	PUNCT
ct-9204	67	1	in	in	ADP
ct-9204	67	2	vitro	vitro	X
ct-9204	67	3	extracellular	extracellular	ADJ
ct-9204	67	4	vesicles	vesicle	NOUN
ct-9204	67	5	production	production	NOUN
ct-9204	67	6	to	to	PART
ct-9204	67	7	improve	improve	VERB
ct-9204	67	8	our	our	PRON
ct-9204	67	9	ability	ability	NOUN
ct-9204	67	10	to	to	PART
ct-9204	67	11	consistently	consistently	ADV
ct-9204	67	12	increase	increase	VERB
ct-9204	67	13	ev	ev	ADP
ct-9204	67	14	production	production	NOUN
ct-9204	67	15	,	,	PUNCT
ct-9204	67	16	much	much	ADJ
ct-9204	67	17	work	work	NOUN
ct-9204	67	18	on	on	ADP
ct-9204	67	19	evs	evs	NOUN
ct-9204	67	20	utilize	utilize	NOUN
ct-9204	67	21	in	in	ADP
ct-9204	67	22	vitro	vitro	X
ct-9204	67	23	produced	produce	VERB
ct-9204	67	24	vesicles	vesicle	NOUN
ct-9204	67	25	from	from	ADP
ct-9204	67	26	cell	cell	NOUN
ct-9204	67	27	lines	line	NOUN
ct-9204	67	28	.	.	PUNCT
ct-9204	68	1	impact	impact	NOUN
ct-9204	68	2	of	of	ADP
ct-9204	68	3	isolation	isolation	NOUN
ct-9204	68	4	and	and	CCONJ
ct-9204	68	5	culture	culture	NOUN
ct-9204	68	6	conditions	condition	NOUN
ct-9204	68	7	on	on	ADP
ct-9204	68	8	ev	ev	ADP
ct-9204	68	9	production	production	NOUN
ct-9204	68	10	has	have	AUX
ct-9204	68	11	been	be	AUX
ct-9204	68	12	reviewed,6	reviewed,6	VERB
ct-9204	68	13	yet	yet	ADV
ct-9204	68	14	much	much	ADJ
ct-9204	68	15	is	be	AUX
ct-9204	68	16	still	still	ADV
ct-9204	68	17	unknown	unknown	ADJ
ct-9204	68	18	,	,	PUNCT
ct-9204	68	19	in	in	ADP
ct-9204	68	20	large	large	ADJ
ct-9204	68	21	part	part	NOUN
ct-9204	68	22	because	because	SCONJ
ct-9204	68	23	our	our	PRON
ct-9204	68	24	understanding	understanding	NOUN
ct-9204	68	25	of	of	ADP
ct-9204	68	26	biogenesis	biogenesis	NOUN
ct-9204	68	27	of	of	ADP
ct-9204	68	28	these	these	DET
ct-9204	68	29	clinical	clinical	ADJ
ct-9204	68	30	theriogenology	theriogenology	NOUN
ct-9204	68	31	•	•	NOUN
ct-9204	68	32	volume	volume	NOUN
ct-9204	68	33	12	12	NUM
ct-9204	68	34	number	number	NOUN
ct-9204	68	35	2	2	NUM
ct-9204	68	36	•	•	NOUN
ct-9204	68	37	june	june	PROPN
ct-9204	68	38	202094	202094	NUM
ct-9204	68	39	vesicles	vesicle	NOUN
ct-9204	68	40	is	be	AUX
ct-9204	68	41	not	not	PART
ct-9204	68	42	fully	fully	ADV
ct-9204	68	43	elucidated	elucidated	ADJ
ct-9204	68	44	.	.	PUNCT
ct-9204	69	1	different	different	ADJ
ct-9204	69	2	cell	cell	NOUN
ct-9204	69	3	types	type	NOUN
ct-9204	69	4	secreted	secrete	VERB
ct-9204	69	5	different	different	ADJ
ct-9204	69	6	amounts	amount	NOUN
ct-9204	69	7	of	of	ADP
ct-9204	69	8	evs	evs	NOUN
ct-9204	69	9	in	in	ADP
ct-9204	69	10	vitro,6	vitro,6	NOUN
ct-9204	69	11	but	but	CCONJ
ct-9204	69	12	whether	whether	SCONJ
ct-9204	69	13	this	this	PRON
ct-9204	69	14	is	be	AUX
ct-9204	69	15	intrinsic	intrinsic	ADJ
ct-9204	69	16	to	to	ADP
ct-9204	69	17	cells	cell	NOUN
ct-9204	69	18	or	or	CCONJ
ct-9204	69	19	perhaps	perhaps	ADV
ct-9204	69	20	in	in	ADP
ct-9204	69	21	response	response	NOUN
ct-9204	69	22	to	to	ADP
ct-9204	69	23	pre	pre	VERB
ct-9204	69	24	-	-	ADJ
ct-9204	69	25	established	established	ADJ
ct-9204	69	26	culture	culture	NOUN
ct-9204	69	27	methods	method	NOUN
ct-9204	69	28	is	be	AUX
ct-9204	69	29	not	not	PART
ct-9204	69	30	certain	certain	ADJ
ct-9204	69	31	.	.	PUNCT
ct-9204	70	1	presence	presence	NOUN
ct-9204	70	2	or	or	CCONJ
ct-9204	70	3	absence	absence	NOUN
ct-9204	70	4	of	of	ADP
ct-9204	70	5	serum	serum	NOUN
ct-9204	70	6	in	in	ADP
ct-9204	70	7	culture	culture	NOUN
ct-9204	70	8	medium	medium	NOUN
ct-9204	70	9	for	for	ADP
ct-9204	70	10	neuroblastoma	neuroblastoma	ADJ
ct-9204	70	11	cells	cell	NOUN
ct-9204	70	12	has	have	AUX
ct-9204	70	13	been	be	AUX
ct-9204	70	14	demonstrated	demonstrate	VERB
ct-9204	70	15	to	to	PART
ct-9204	70	16	alter	alter	VERB
ct-9204	70	17	both	both	DET
ct-9204	70	18	quantity	quantity	NOUN
ct-9204	70	19	of	of	ADP
ct-9204	70	20	produced	produce	VERB
ct-9204	70	21	evs	evs	NOUN
ct-9204	70	22	as	as	ADV
ct-9204	70	23	well	well	ADV
ct-9204	70	24	as	as	ADP
ct-9204	70	25	their	their	PRON
ct-9204	70	26	protein	protein	NOUN
ct-9204	70	27	expression	expression	NOUN
ct-9204	70	28	levels.100alterations	levels.100alteration	NOUN
ct-9204	70	29	in	in	ADP
ct-9204	70	30	lipid	lipid	NOUN
ct-9204	70	31	composition	composition	NOUN
ct-9204	70	32	are	be	AUX
ct-9204	70	33	also	also	ADV
ct-9204	70	34	apparent	apparent	ADJ
ct-9204	70	35	from	from	ADP
ct-9204	70	36	cell	cell	NOUN
ct-9204	70	37	lines	line	NOUN
ct-9204	70	38	from	from	ADP
ct-9204	70	39	same	same	ADJ
ct-9204	70	40	organ	organ	NOUN
ct-9204	70	41	,	,	PUNCT
ct-9204	70	42	as	as	SCONJ
ct-9204	70	43	lipid	lipid	NOUN
ct-9204	70	44	profiling	profiling	NOUN
ct-9204	70	45	of	of	ADP
ct-9204	70	46	prostate	prostate	NOUN
ct-9204	70	47	-	-	PUNCT
ct-9204	70	48	derived	derive	VERB
ct-9204	70	49	cell	cell	NOUN
ct-9204	70	50	line	line	NOUN
ct-9204	70	51	evs	evs	PROPN
ct-9204	70	52	identified	identify	VERB
ct-9204	70	53	differences	difference	NOUN
ct-9204	70	54	in	in	ADP
ct-9204	70	55	molecular	molecular	ADJ
ct-9204	70	56	lipids	lipid	NOUN
ct-9204	70	57	between	between	ADP
ct-9204	70	58	cell	cell	NOUN
ct-9204	70	59	lines	line	NOUN
ct-9204	70	60	with	with	ADP
ct-9204	70	61	different	different	ADJ
ct-9204	70	62	tumorgenicity.101	tumorgenicity.101	NOUN
ct-9204	70	63	although	although	SCONJ
ct-9204	70	64	culture	culture	NOUN
ct-9204	70	65	conditions	condition	NOUN
ct-9204	70	66	,	,	PUNCT
ct-9204	70	67	once	once	ADV
ct-9204	70	68	optimized	optimize	VERB
ct-9204	70	69	,	,	PUNCT
ct-9204	70	70	should	should	AUX
ct-9204	70	71	allow	allow	VERB
ct-9204	70	72	for	for	ADP
ct-9204	70	73	production	production	NOUN
ct-9204	70	74	of	of	ADP
ct-9204	70	75	evs	evs	NOUN
ct-9204	70	76	with	with	ADP
ct-9204	70	77	definable	definable	ADJ
ct-9204	70	78	characteristics	characteristic	NOUN
ct-9204	70	79	,	,	PUNCT
ct-9204	70	80	high	high	ADJ
ct-9204	70	81	throughput	throughput	NOUN
ct-9204	70	82	production	production	NOUN
ct-9204	70	83	remains	remain	VERB
ct-9204	70	84	challenging.102	challenging.102	ADP
ct-9204	70	85	owing	owe	VERB
ct-9204	70	86	to	to	ADP
ct-9204	70	87	broad	broad	ADJ
ct-9204	70	88	interest	interest	NOUN
ct-9204	70	89	in	in	ADP
ct-9204	70	90	evs	evs	NOUN
ct-9204	70	91	in	in	ADP
ct-9204	70	92	regenerative	regenerative	ADJ
ct-9204	70	93	medicine	medicine	NOUN
ct-9204	70	94	and	and	CCONJ
ct-9204	70	95	cancer	cancer	NOUN
ct-9204	70	96	research	research	NOUN
ct-9204	70	97	,	,	PUNCT
ct-9204	70	98	this	this	DET
ct-9204	70	99	area	area	NOUN
ct-9204	70	100	has	have	AUX
ct-9204	70	101	already	already	ADV
ct-9204	70	102	begun	begin	VERB
ct-9204	70	103	to	to	PART
ct-9204	70	104	be	be	AUX
ct-9204	70	105	explored	explore	VERB
ct-9204	70	106	.	.	PUNCT
ct-9204	71	1	ev	ev	PRON
ct-9204	71	2	production	production	NOUN
ct-9204	71	3	from	from	ADP
ct-9204	71	4	prostate	prostate	NOUN
ct-9204	71	5	cancer	cancer	NOUN
ct-9204	71	6	cells	cell	NOUN
ct-9204	71	7	is	be	AUX
ct-9204	71	8	significantly	significantly	ADV
ct-9204	71	9	improved	improve	VERB
ct-9204	71	10	when	when	SCONJ
ct-9204	71	11	cells	cell	NOUN
ct-9204	71	12	are	be	AUX
ct-9204	71	13	cultured	cultured	ADJ
ct-9204	71	14	in	in	ADP
ct-9204	71	15	a	a	DET
ct-9204	71	16	bioreactor	bioreactor	NOUN
ct-9204	71	17	compared	compare	VERB
ct-9204	71	18	to	to	ADP
ct-9204	71	19	a	a	DET
ct-9204	71	20	conventional	conventional	ADJ
ct-9204	71	21	system,103	system,103	NOUN
ct-9204	71	22	with	with	ADP
ct-9204	71	23	ev	ev	ADP
ct-9204	71	24	morphology	morphology	NOUN
ct-9204	71	25	and	and	CCONJ
ct-9204	71	26	select	select	VERB
ct-9204	71	27	surface	surface	NOUN
ct-9204	71	28	markers	marker	NOUN
ct-9204	71	29	not	not	PART
ct-9204	71	30	different	different	ADJ
ct-9204	71	31	between	between	ADP
ct-9204	71	32	these	these	DET
ct-9204	71	33	2	2	NUM
ct-9204	71	34	conditions	condition	NOUN
ct-9204	71	35	.	.	PUNCT
ct-9204	72	1	however	however	ADV
ct-9204	72	2	,	,	PUNCT
ct-9204	72	3	metabolic	metabolic	NOUN
ct-9204	72	4	analyses	analysis	NOUN
ct-9204	72	5	indicated	indicate	VERB
ct-9204	72	6	differences	difference	NOUN
ct-9204	72	7	in	in	ADP
ct-9204	72	8	ev	ev	ADP
ct-9204	72	9	composition	composition	NOUN
ct-9204	72	10	between	between	ADP
ct-9204	72	11	conventional	conventional	ADJ
ct-9204	72	12	versus	versus	ADP
ct-9204	72	13	bioreactor	bioreactor	NOUN
ct-9204	72	14	derived	derive	VERB
ct-9204	72	15	evs	evs	NOUN
ct-9204	72	16	,	,	PUNCT
ct-9204	72	17	particularly	particularly	ADV
ct-9204	72	18	with	with	ADP
ct-9204	72	19	regard	regard	NOUN
ct-9204	72	20	to	to	ADP
ct-9204	72	21	lipid	lipid	NOUN
ct-9204	72	22	contents	content	NOUN
ct-9204	72	23	.	.	PUNCT
ct-9204	73	1	a	a	DET
ct-9204	73	2	3d	3d	NUM
ct-9204	73	3	printer	printer	NOUN
ct-9204	73	4	fabricated	fabricate	VERB
ct-9204	73	5	bioreactor	bioreactor	NOUN
ct-9204	73	6	has	have	AUX
ct-9204	73	7	also	also	ADV
ct-9204	73	8	been	be	AUX
ct-9204	73	9	shown	show	VERB
ct-9204	73	10	to	to	PART
ct-9204	73	11	enhance	enhance	VERB
ct-9204	73	12	ev	ev	ADP
ct-9204	73	13	production	production	NOUN
ct-9204	73	14	for	for	ADP
ct-9204	73	15	human	human	ADJ
ct-9204	73	16	endothelial	endothelial	NOUN
ct-9204	73	17	cells.104	cells.104	NOUN
ct-9204	73	18	still	still	ADV
ct-9204	73	19	,	,	PUNCT
ct-9204	73	20	as	as	SCONJ
ct-9204	73	21	trauma	trauma	NOUN
ct-9204	73	22	and	and	CCONJ
ct-9204	73	23	cell	cell	NOUN
ct-9204	73	24	stress	stress	NOUN
ct-9204	73	25	have	have	AUX
ct-9204	73	26	also	also	ADV
ct-9204	73	27	been	be	AUX
ct-9204	73	28	demonstrated	demonstrate	VERB
ct-9204	73	29	to	to	PART
ct-9204	73	30	increase	increase	VERB
ct-9204	73	31	ev	ev	ADP
ct-9204	73	32	secretion105	secretion105	PROPN
ct-9204	73	33	and	and	CCONJ
ct-9204	73	34	mrna	mrna	PROPN
ct-9204	73	35	/	/	SYM
ct-9204	73	36	protein	protein	NOUN
ct-9204	73	37	compositions,106	compositions,106	X
ct-9204	73	38	respectively	respectively	ADV
ct-9204	73	39	.	.	PUNCT
ct-9204	74	1	mechanical	mechanical	ADJ
ct-9204	74	2	forces	force	NOUN
ct-9204	74	3	on	on	ADP
ct-9204	74	4	cells	cell	NOUN
ct-9204	74	5	are	be	AUX
ct-9204	74	6	known	know	VERB
ct-9204	74	7	to	to	PART
ct-9204	74	8	promote	promote	VERB
ct-9204	74	9	exocytosis,107	exocytosis,107	NOUN
ct-9204	74	10	therefore	therefore	ADV
ct-9204	74	11	it	it	PRON
ct-9204	74	12	is	be	AUX
ct-9204	74	13	also	also	ADV
ct-9204	74	14	possible	possible	ADJ
ct-9204	74	15	that	that	SCONJ
ct-9204	74	16	shear	shear	NOUN
ct-9204	74	17	forces	force	NOUN
ct-9204	74	18	on	on	ADP
ct-9204	74	19	cells	cell	NOUN
ct-9204	74	20	grown	grow	VERB
ct-9204	74	21	in	in	ADP
ct-9204	74	22	bioreactor	bioreactor	NOUN
ct-9204	74	23	systems	system	NOUN
ct-9204	74	24	may	may	AUX
ct-9204	74	25	be	be	AUX
ct-9204	74	26	stimulating	stimulate	VERB
ct-9204	74	27	mechanical	mechanical	ADJ
ct-9204	74	28	,	,	PUNCT
ct-9204	74	29	stress	stress	NOUN
ct-9204	74	30	-	-	PUNCT
ct-9204	74	31	driven	drive	VERB
ct-9204	74	32	ev	ev	ADP
ct-9204	74	33	production	production	NOUN
ct-9204	74	34	.	.	PUNCT
ct-9204	75	1	under	under	ADP
ct-9204	75	2	these	these	DET
ct-9204	75	3	conditions	condition	NOUN
ct-9204	75	4	,	,	PUNCT
ct-9204	75	5	ev	ev	DET
ct-9204	75	6	composition	composition	NOUN
ct-9204	75	7	is	be	AUX
ct-9204	75	8	likely	likely	ADV
ct-9204	75	9	altered	alter	VERB
ct-9204	75	10	and	and	CCONJ
ct-9204	75	11	,	,	PUNCT
ct-9204	75	12	potentially	potentially	ADV
ct-9204	75	13	,	,	PUNCT
ct-9204	75	14	less	less	ADV
ct-9204	75	15	efficacious	efficacious	ADJ
ct-9204	75	16	.	.	PUNCT
ct-9204	76	1	more	more	ADJ
ct-9204	76	2	studies	study	NOUN
ct-9204	76	3	are	be	AUX
ct-9204	76	4	needed	need	VERB
ct-9204	76	5	to	to	PART
ct-9204	76	6	assess	assess	VERB
ct-9204	76	7	:	:	PUNCT
ct-9204	76	8	1	1	X
ct-9204	76	9	)	)	PUNCT
ct-9204	76	10	if	if	SCONJ
ct-9204	76	11	dynamic	dynamic	ADJ
ct-9204	76	12	culture	culture	NOUN
ct-9204	76	13	systems	system	NOUN
ct-9204	76	14	consistently	consistently	ADV
ct-9204	76	15	result	result	VERB
ct-9204	76	16	in	in	ADP
ct-9204	76	17	improved	improve	VERB
ct-9204	76	18	ev	ev	ADP
ct-9204	76	19	production	production	NOUN
ct-9204	76	20	across	across	ADP
ct-9204	76	21	cell	cell	NOUN
ct-9204	76	22	types	type	NOUN
ct-9204	76	23	,	,	PUNCT
ct-9204	76	24	compared	compare	VERB
ct-9204	76	25	to	to	ADP
ct-9204	76	26	conventional	conventional	ADJ
ct-9204	76	27	culture	culture	NOUN
ct-9204	76	28	;	;	PUNCT
ct-9204	76	29	and	and	CCONJ
ct-9204	76	30	2	2	X
ct-9204	76	31	)	)	PUNCT
ct-9204	76	32	how	how	SCONJ
ct-9204	76	33	quality	quality	NOUN
ct-9204	76	34	/	/	SYM
ct-9204	76	35	composition	composition	NOUN
ct-9204	76	36	/	/	SYM
ct-9204	76	37	functionality	functionality	NOUN
ct-9204	76	38	of	of	ADP
ct-9204	76	39	these	these	DET
ct-9204	76	40	evs	evs	NOUN
ct-9204	76	41	compare	compare	VERB
ct-9204	76	42	with	with	ADP
ct-9204	76	43	in	in	ADP
ct-9204	76	44	vivo	vivo	NOUN
ct-9204	76	45	-	-	PUNCT
ct-9204	76	46	derived	derive	VERB
ct-9204	76	47	counterparts	counterpart	NOUN
ct-9204	76	48	and/or	and/or	CCONJ
ct-9204	76	49	those	those	PRON
ct-9204	76	50	produced	produce	VERB
ct-9204	76	51	by	by	ADP
ct-9204	76	52	conventional	conventional	ADJ
ct-9204	76	53	culture	culture	NOUN
ct-9204	76	54	systems	system	NOUN
ct-9204	76	55	.	.	PUNCT
ct-9204	77	1	in	in	ADP
ct-9204	77	2	a	a	DET
ct-9204	77	3	sense	sense	NOUN
ct-9204	77	4	,	,	PUNCT
ct-9204	77	5	platforms	platform	NOUN
ct-9204	77	6	for	for	ADP
ct-9204	77	7	improved	improve	VERB
ct-9204	77	8	in	in	ADP
ct-9204	77	9	vitro	vitro	X
ct-9204	77	10	production	production	NOUN
ct-9204	77	11	of	of	ADP
ct-9204	77	12	reproductive	reproductive	ADJ
ct-9204	77	13	ev	ev	PROPN
ct-9204	77	14	are	be	AUX
ct-9204	77	15	already	already	ADV
ct-9204	77	16	in	in	ADP
ct-9204	77	17	progress	progress	NOUN
ct-9204	77	18	.	.	PUNCT
ct-9204	78	1	organs	organ	NOUN
ct-9204	78	2	on	on	ADP
ct-9204	78	3	a	a	DET
ct-9204	78	4	chip	chip	NOUN
ct-9204	78	5	technology	technology	NOUN
ct-9204	78	6	,	,	PUNCT
ct-9204	78	7	which	which	PRON
ct-9204	78	8	has	have	AUX
ct-9204	78	9	been	be	AUX
ct-9204	78	10	applied	apply	VERB
ct-9204	78	11	to	to	PART
ct-9204	78	12	recreate	recreate	VERB
ct-9204	78	13	in	in	ADP
ct-9204	78	14	vitro	vitro	X
ct-9204	78	15	microenvironment	microenvironment	NOUN
ct-9204	78	16	in	in	ADP
ct-9204	78	17	more	more	ADV
ct-9204	78	18	naturalistic	naturalistic	ADJ
ct-9204	78	19	conditions	condition	NOUN
ct-9204	78	20	by	by	ADP
ct-9204	78	21	mimicking	mimic	VERB
ct-9204	78	22	tissue	tissue	NOUN
ct-9204	78	23	architecture	architecture	NOUN
ct-9204	78	24	,	,	PUNCT
ct-9204	78	25	cell	cell	NOUN
ct-9204	78	26	heterogeneity	heterogeneity	NOUN
ct-9204	78	27	,	,	PUNCT
ct-9204	78	28	and	and	CCONJ
ct-9204	78	29	dynamic	dynamic	ADJ
ct-9204	78	30	exposure	exposure	NOUN
ct-9204	78	31	to	to	ADP
ct-9204	78	32	nutrients	nutrient	NOUN
ct-9204	78	33	,	,	PUNCT
ct-9204	78	34	growth	growth	NOUN
ct-9204	78	35	factors	factor	NOUN
ct-9204	78	36	and	and	CCONJ
ct-9204	78	37	hormones	hormone	NOUN
ct-9204	78	38	,	,	PUNCT
ct-9204	78	39	represent	represent	VERB
ct-9204	78	40	microfluidic	microfluidic	ADJ
ct-9204	78	41	bioreactors	bioreactor	NOUN
ct-9204	78	42	.	.	PUNCT
ct-9204	79	1	automated	automate	VERB
ct-9204	79	2	and	and	CCONJ
ct-9204	79	3	controlled	control	VERB
ct-9204	79	4	flow	flow	NOUN
ct-9204	79	5	with	with	ADP
ct-9204	79	6	specifically	specifically	ADV
ct-9204	79	7	timed	time	VERB
ct-9204	79	8	hormone	hormone	NOUN
ct-9204	79	9	supplementations	supplementation	NOUN
ct-9204	79	10	can	can	AUX
ct-9204	79	11	mimic	mimic	VERB
ct-9204	79	12	normal	normal	ADJ
ct-9204	79	13	pulsatile	pulsatile	NOUN
ct-9204	79	14	hormone	hormone	NOUN
ct-9204	79	15	pattern	pattern	NOUN
ct-9204	79	16	of	of	ADP
ct-9204	79	17	reproductive	reproductive	ADJ
ct-9204	79	18	cycle	cycle	NOUN
ct-9204	79	19	,	,	PUNCT
ct-9204	79	20	and	and	CCONJ
ct-9204	79	21	flow	flow	NOUN
ct-9204	79	22	-	-	PUNCT
ct-9204	79	23	through	through	ADP
ct-9204	79	24	containing	contain	VERB
ct-9204	79	25	evs	evs	NOUN
ct-9204	79	26	readily	readily	ADV
ct-9204	79	27	collected	collect	VERB
ct-9204	79	28	(	(	PUNCT
ct-9204	79	29	figure	figure	NOUN
ct-9204	79	30	3b	3b	NUM
ct-9204	79	31	)	)	PUNCT
ct-9204	79	32	.	.	PUNCT
ct-9204	80	1	a	a	DET
ct-9204	80	2	bovine	bovine	NOUN
ct-9204	80	3	oviduct	oviduct	NOUN
ct-9204	80	4	-	-	PUNCT
ct-9204	80	5	on	on	ADP
ct-9204	80	6	-	-	PUNCT
ct-9204	80	7	a	a	DET
ct-9204	80	8	-	-	PUNCT
ct-9204	80	9	chip	chip	NOUN
ct-9204	80	10	,	,	PUNCT
ct-9204	80	11	mimicking	mimic	VERB
ct-9204	80	12	in	in	ADP
ct-9204	80	13	vivo	vivo	ADJ
ct-9204	80	14	conditions	condition	NOUN
ct-9204	80	15	in	in	ADP
ct-9204	80	16	this	this	DET
ct-9204	80	17	organ	organ	NOUN
ct-9204	80	18	,	,	PUNCT
ct-9204	80	19	demonstrated	demonstrate	VERB
ct-9204	80	20	epigenetic	epigenetic	ADJ
ct-9204	80	21	patterns	pattern	NOUN
ct-9204	80	22	of	of	ADP
ct-9204	80	23	chip	chip	NOUN
ct-9204	80	24	derived	derive	VERB
ct-9204	80	25	embryos	embryo	NOUN
ct-9204	80	26	to	to	PART
ct-9204	80	27	be	be	AUX
ct-9204	80	28	more	more	ADV
ct-9204	80	29	similar	similar	ADJ
ct-9204	80	30	to	to	ADP
ct-9204	80	31	fresh	fresh	ADJ
ct-9204	80	32	controls	control	NOUN
ct-9204	80	33	than	than	ADP
ct-9204	80	34	those	those	PRON
ct-9204	80	35	produced	produce	VERB
ct-9204	80	36	via	via	ADP
ct-9204	80	37	conventional	conventional	ADJ
ct-9204	80	38	ivf.108	ivf.108	NOUN
ct-9204	80	39	an	an	DET
ct-9204	80	40	artificial	artificial	ADJ
ct-9204	80	41	uterus	uterus	NOUN
ct-9204	80	42	has	have	AUX
ct-9204	80	43	similarly	similarly	ADV
ct-9204	80	44	been	be	AUX
ct-9204	80	45	produced	produce	VERB
ct-9204	80	46	via	via	ADP
ct-9204	80	47	microfluidic	microfluidic	ADJ
ct-9204	80	48	chip	chip	NOUN
ct-9204	80	49	,	,	PUNCT
ct-9204	80	50	consisting	consist	VERB
ct-9204	80	51	of	of	ADP
ct-9204	80	52	figure	figure	NOUN
ct-9204	80	53	3	3	NUM
ct-9204	80	54	.	.	PUNCT
ct-9204	81	1	in	in	ADP
ct-9204	81	2	vivo	vivo	NOUN
ct-9204	81	3	and	and	CCONJ
ct-9204	81	4	vitro	vitro	X
ct-9204	81	5	alternatives	alternative	NOUN
ct-9204	81	6	for	for	ADP
ct-9204	81	7	collection	collection	NOUN
ct-9204	81	8	of	of	ADP
ct-9204	81	9	evs	evs	NOUN
ct-9204	81	10	,	,	PUNCT
ct-9204	81	11	with	with	ADP
ct-9204	81	12	:	:	PUNCT
ct-9204	81	13	a	a	DET
ct-9204	81	14	)	)	PUNCT
ct-9204	81	15	flush	flush	NOUN
ct-9204	81	16	of	of	ADP
ct-9204	81	17	fluids	fluid	NOUN
ct-9204	81	18	containing	contain	VERB
ct-9204	81	19	ev	ev	INTJ
ct-9204	81	20	from	from	ADP
ct-9204	81	21	domestic	domestic	ADJ
ct-9204	81	22	cat	cat	NOUN
ct-9204	81	23	oviducts	oviduct	NOUN
ct-9204	81	24	,	,	PUNCT
ct-9204	81	25	versus	versus	ADP
ct-9204	81	26	b	b	X
ct-9204	81	27	)	)	PUNCT
ct-9204	81	28	dynamic	dynamic	ADJ
ct-9204	81	29	fluidic	fluidic	ADJ
ct-9204	81	30	culture	culture	NOUN
ct-9204	81	31	system	system	NOUN
ct-9204	81	32	where	where	SCONJ
ct-9204	81	33	tissues	tissue	NOUN
ct-9204	81	34	/	/	SYM
ct-9204	81	35	cells	cell	NOUN
ct-9204	81	36	of	of	ADP
ct-9204	81	37	interest	interest	NOUN
ct-9204	81	38	can	can	AUX
ct-9204	81	39	be	be	AUX
ct-9204	81	40	maintained	maintain	VERB
ct-9204	81	41	in	in	ADP
ct-9204	81	42	channels	channel	NOUN
ct-9204	81	43	(	(	PUNCT
ct-9204	81	44	inset	inset	NOUN
ct-9204	81	45	)	)	PUNCT
ct-9204	81	46	with	with	ADP
ct-9204	81	47	culture	culture	NOUN
ct-9204	81	48	medium	medium	NOUN
ct-9204	81	49	delivered	deliver	VERB
ct-9204	81	50	via	via	ADP
ct-9204	81	51	syringe	syringe	NOUN
ct-9204	81	52	pump	pump	NOUN
ct-9204	81	53	and	and	CCONJ
ct-9204	81	54	flow	flow	VERB
ct-9204	81	55	through	through	ADP
ct-9204	81	56	containing	contain	VERB
ct-9204	81	57	ev	ev	INTJ
ct-9204	81	58	collected	collect	VERB
ct-9204	81	59	in	in	ADP
ct-9204	81	60	tubes	tube	NOUN
ct-9204	81	61	.	.	PUNCT
ct-9204	82	1	clinical	clinical	ADJ
ct-9204	82	2	theriogenology	theriogenology	NOUN
ct-9204	82	3	•	•	NOUN
ct-9204	82	4	volume	volume	NOUN
ct-9204	82	5	12	12	NUM
ct-9204	82	6	number	number	NOUN
ct-9204	82	7	2	2	NUM
ct-9204	82	8	•	•	NOUN
ct-9204	82	9	june	june	PROPN
ct-9204	82	10	2020	2020	NUM
ct-9204	82	11	95	95	NUM
ct-9204	82	12	two	two	NUM
ct-9204	82	13	channels	channel	NOUN
ct-9204	82	14	separated	separate	VERB
ct-9204	82	15	with	with	ADP
ct-9204	82	16	a	a	DET
ct-9204	82	17	porous	porous	ADJ
ct-9204	82	18	membrane	membrane	NOUN
ct-9204	82	19	,	,	PUNCT
ct-9204	82	20	with	with	ADP
ct-9204	82	21	cell	cell	NOUN
ct-9204	82	22	culture	culture	NOUN
ct-9204	82	23	(	(	PUNCT
ct-9204	82	24	endometrial	endometrial	ADJ
ct-9204	82	25	and	and	CCONJ
ct-9204	82	26	embryos	embryo	NOUN
ct-9204	82	27	)	)	PUNCT
ct-9204	82	28	on	on	ADP
ct-9204	82	29	apical	apical	ADJ
ct-9204	82	30	side	side	NOUN
ct-9204	82	31	and	and	CCONJ
ct-9204	82	32	perfusion	perfusion	NOUN
ct-9204	82	33	on	on	ADP
ct-9204	82	34	basolateral.109	basolateral.109	VERB
ct-9204	82	35	higher	high	ADJ
ct-9204	82	36	rates	rate	NOUN
ct-9204	82	37	of	of	ADP
ct-9204	82	38	blastocyst	blastocyst	NOUN
ct-9204	82	39	development	development	NOUN
ct-9204	82	40	were	be	AUX
ct-9204	82	41	obtained	obtain	VERB
ct-9204	82	42	in	in	ADP
ct-9204	82	43	chip	chip	NOUN
ct-9204	82	44	compared	compare	VERB
ct-9204	82	45	to	to	ADP
ct-9204	82	46	a	a	DET
ct-9204	82	47	conventional	conventional	ADJ
ct-9204	82	48	petri	petri	ADJ
ct-9204	82	49	dish	dish	NOUN
ct-9204	82	50	.	.	PUNCT
ct-9204	83	1	no	no	DET
ct-9204	83	2	microfluidic	microfluidic	ADJ
ct-9204	83	3	systems	system	NOUN
ct-9204	83	4	for	for	ADP
ct-9204	83	5	vaginal	vaginal	ADJ
ct-9204	83	6	cells	cell	NOUN
ct-9204	83	7	have	have	AUX
ct-9204	83	8	been	be	AUX
ct-9204	83	9	reported	report	VERB
ct-9204	83	10	,	,	PUNCT
ct-9204	83	11	though	though	SCONJ
ct-9204	83	12	a	a	DET
ct-9204	83	13	human	human	ADJ
ct-9204	83	14	vaginal	vaginal	ADJ
ct-9204	83	15	epithelial	epithelial	ADJ
ct-9204	83	16	cell	cell	NOUN
ct-9204	83	17	model	model	NOUN
ct-9204	83	18	with	with	ADP
ct-9204	83	19	3d	3d	PROPN
ct-9204	83	20	organoid	organoid	PROPN
ct-9204	83	21	culture	culture	NOUN
ct-9204	83	22	has	have	AUX
ct-9204	83	23	been	be	AUX
ct-9204	83	24	described.110	described.110	VERB
ct-9204	83	25	a	a	DET
ct-9204	83	26	combination	combination	NOUN
ct-9204	83	27	ovary	ovary	ADJ
ct-9204	83	28	,	,	PUNCT
ct-9204	83	29	fallopian	fallopian	ADJ
ct-9204	83	30	tube	tube	NOUN
ct-9204	83	31	,	,	PUNCT
ct-9204	83	32	uterus	uterus	NOUN
ct-9204	83	33	,	,	PUNCT
ct-9204	83	34	cervix	cervix	NOUN
ct-9204	83	35	,	,	PUNCT
ct-9204	83	36	and	and	CCONJ
ct-9204	83	37	liver	liver	NOUN
ct-9204	83	38	reproductive	reproductive	ADJ
ct-9204	83	39	system	system	NOUN
ct-9204	83	40	on	on	ADP
ct-9204	83	41	a	a	DET
ct-9204	83	42	chip	chip	NOUN
ct-9204	83	43	with	with	ADP
ct-9204	83	44	human	human	ADJ
ct-9204	83	45	and	and	CCONJ
ct-9204	83	46	murine	murine	ADJ
ct-9204	83	47	tissues	tissue	NOUN
ct-9204	83	48	/	/	SYM
ct-9204	83	49	cells	cell	NOUN
ct-9204	83	50	has	have	AUX
ct-9204	83	51	been	be	AUX
ct-9204	83	52	produced	produce	VERB
ct-9204	83	53	(	(	PUNCT
ct-9204	83	54	termed	term	VERB
ct-9204	83	55	evatar	evatar	NOUN
ct-9204	83	56	)	)	PUNCT
ct-9204	83	57	,	,	PUNCT
ct-9204	83	58	that	that	PRON
ct-9204	83	59	mimics	mimic	VERB
ct-9204	83	60	hormonal	hormonal	ADJ
ct-9204	83	61	profiles	profile	NOUN
ct-9204	83	62	of	of	ADP
ct-9204	83	63	human	human	ADJ
ct-9204	83	64	menstrual	menstrual	ADJ
ct-9204	83	65	cycle	cycle	NOUN
ct-9204	83	66	in	in	ADP
ct-9204	83	67	vitro.111	vitro.111	PROPN
ct-9204	83	68	we	we	PRON
ct-9204	83	69	have	have	AUX
ct-9204	83	70	previously	previously	ADV
ct-9204	83	71	described	describe	VERB
ct-9204	83	72	an	an	DET
ct-9204	83	73	ovary	ovary	ADJ
ct-9204	83	74	-	-	PUNCT
ct-9204	83	75	on	on	ADP
ct-9204	83	76	-	-	PUNCT
ct-9204	83	77	a	a	DET
ct-9204	83	78	-	-	PUNCT
ct-9204	83	79	chip	chip	NOUN
ct-9204	83	80	for	for	ADP
ct-9204	83	81	culture	culture	NOUN
ct-9204	83	82	of	of	ADP
ct-9204	83	83	domestic	domestic	ADJ
ct-9204	83	84	dog	dog	NOUN
ct-9204	83	85	and	and	CCONJ
ct-9204	83	86	cat	cat	NOUN
ct-9204	83	87	ovarian	ovarian	PROPN
ct-9204	83	88	tissues,112	tissues,112	PROPN
ct-9204	83	89	and	and	CCONJ
ct-9204	83	90	substantial	substantial	ADJ
ct-9204	83	91	strides	stride	NOUN
ct-9204	83	92	have	have	AUX
ct-9204	83	93	been	be	AUX
ct-9204	83	94	made	make	VERB
ct-9204	83	95	in	in	ADP
ct-9204	83	96	development	development	NOUN
ct-9204	83	97	of	of	ADP
ct-9204	83	98	in	in	ADP
ct-9204	83	99	vitro	vitro	X
ct-9204	83	100	spermatogenesis	spermatogenesis	NOUN
ct-9204	83	101	with	with	ADP
ct-9204	83	102	testis	testis	NOUN
ct-9204	83	103	on	on	ADP
ct-9204	83	104	chip	chip	NOUN
ct-9204	83	105	in	in	ADP
ct-9204	83	106	recent	recent	ADJ
ct-9204	83	107	years.113	years.113	NOUN
ct-9204	83	108	-	-	PUNCT
ct-9204	83	109	115	115	NUM
ct-9204	83	110	conversely	conversely	ADV
ct-9204	83	111	,	,	PUNCT
ct-9204	83	112	microfluidic	microfluidic	ADJ
ct-9204	83	113	or	or	CCONJ
ct-9204	83	114	bioreactor	bioreactor	NOUN
ct-9204	83	115	systems	system	NOUN
ct-9204	83	116	for	for	ADP
ct-9204	83	117	accessory	accessory	ADJ
ct-9204	83	118	sex	sex	NOUN
ct-9204	83	119	glands	gland	NOUN
ct-9204	83	120	and/or	and/or	CCONJ
ct-9204	83	121	epididymis	epididymis	NOUN
ct-9204	83	122	are	be	AUX
ct-9204	83	123	lacking	lack	VERB
ct-9204	83	124	.	.	PUNCT
ct-9204	84	1	still	still	ADV
ct-9204	84	2	,	,	PUNCT
ct-9204	84	3	3d	3d	PROPN
ct-9204	84	4	prostate	prostate	NOUN
ct-9204	84	5	organoid	organoid	NOUN
ct-9204	84	6	cultures	culture	NOUN
ct-9204	84	7	(	(	PUNCT
ct-9204	84	8	human	human	NOUN
ct-9204	84	9	and	and	CCONJ
ct-9204	84	10	mouse	mouse	NOUN
ct-9204	84	11	sources	source	NOUN
ct-9204	84	12	)	)	PUNCT
ct-9204	84	13	have	have	AUX
ct-9204	84	14	been	be	AUX
ct-9204	84	15	described116	described116	PROPN
ct-9204	84	16	for	for	ADP
ct-9204	84	17	application	application	NOUN
ct-9204	84	18	primarily	primarily	ADV
ct-9204	84	19	to	to	ADP
ct-9204	84	20	prostate	prostate	NOUN
ct-9204	84	21	cancer	cancer	NOUN
ct-9204	84	22	research	research	NOUN
ct-9204	84	23	.	.	PUNCT
ct-9204	85	1	moreover	moreover	ADV
ct-9204	85	2	,	,	PUNCT
ct-9204	85	3	coculture	coculture	NOUN
ct-9204	85	4	of	of	ADP
ct-9204	85	5	human	human	ADJ
ct-9204	85	6	cauda	cauda	NOUN
ct-9204	85	7	epididymal	epididymal	ADJ
ct-9204	85	8	epithelial	epithelial	ADJ
ct-9204	85	9	cells	cell	NOUN
ct-9204	85	10	(	(	PUNCT
ct-9204	85	11	spheroids	spheroid	NOUN
ct-9204	85	12	)	)	PUNCT
ct-9204	85	13	with	with	ADP
ct-9204	85	14	caput	caput	NOUN
ct-9204	85	15	epididymal	epididymal	ADJ
ct-9204	85	16	sperm	sperm	NOUN
ct-9204	85	17	improved	improve	VERB
ct-9204	85	18	sperm	sperm	NOUN
ct-9204	85	19	motility	motility	NOUN
ct-9204	85	20	and	and	CCONJ
ct-9204	85	21	zp	zp	NOUN
ct-9204	85	22	-	-	ADJ
ct-9204	85	23	binding	bind	VERB
ct-9204	85	24	compared	compare	VERB
ct-9204	85	25	to	to	ADP
ct-9204	85	26	non	non	ADJ
ct-9204	85	27	-	-	ADJ
ct-9204	85	28	cocultured	cocultured	ADJ
ct-9204	85	29	controls.117	controls.117	NOUN
ct-9204	85	30	although	although	SCONJ
ct-9204	85	31	ev	ev	DET
ct-9204	85	32	production	production	NOUN
ct-9204	85	33	has	have	AUX
ct-9204	85	34	not	not	PART
ct-9204	85	35	been	be	AUX
ct-9204	85	36	specifically	specifically	ADV
ct-9204	85	37	compared	compare	VERB
ct-9204	85	38	with	with	ADP
ct-9204	85	39	regards	regard	NOUN
ct-9204	85	40	to	to	ADP
ct-9204	85	41	culture	culture	NOUN
ct-9204	85	42	system	system	NOUN
ct-9204	85	43	in	in	ADP
ct-9204	85	44	any	any	PRON
ct-9204	85	45	of	of	ADP
ct-9204	85	46	described	describe	VERB
ct-9204	85	47	dynamic	dynamic	ADJ
ct-9204	85	48	and/or	and/or	CCONJ
ct-9204	85	49	3d	3d	NUM
ct-9204	85	50	culture	culture	NOUN
ct-9204	85	51	systems	system	NOUN
ct-9204	85	52	,	,	PUNCT
ct-9204	85	53	we	we	PRON
ct-9204	85	54	are	be	AUX
ct-9204	85	55	optimistic	optimistic	ADJ
ct-9204	85	56	that	that	SCONJ
ct-9204	85	57	tools	tool	NOUN
ct-9204	85	58	being	be	AUX
ct-9204	85	59	developed	develop	VERB
ct-9204	85	60	to	to	PART
ct-9204	85	61	produce	produce	VERB
ct-9204	85	62	improved	improve	VERB
ct-9204	85	63	in	in	ADP
ct-9204	85	64	vitro	vitro	X
ct-9204	85	65	models	model	NOUN
ct-9204	85	66	of	of	ADP
ct-9204	85	67	reproductive	reproductive	ADJ
ct-9204	85	68	organs	organ	NOUN
ct-9204	85	69	have	have	VERB
ct-9204	85	70	potential	potential	NOUN
ct-9204	85	71	to	to	PART
ct-9204	85	72	serve	serve	VERB
ct-9204	85	73	as	as	ADP
ct-9204	85	74	controllable	controllable	ADJ
ct-9204	85	75	sources	source	NOUN
ct-9204	85	76	of	of	ADP
ct-9204	85	77	reproductive	reproductive	ADJ
ct-9204	85	78	evs	evs	NOUN
ct-9204	85	79	for	for	ADP
ct-9204	85	80	art	art	NOUN
ct-9204	85	81	as	as	ADV
ct-9204	85	82	well	well	ADV
ct-9204	85	83	.	.	PUNCT
ct-9204	86	1	synthetic	synthetic	ADJ
ct-9204	86	2	or	or	CCONJ
ct-9204	86	3	manufactured	manufacture	VERB
ct-9204	86	4	extracellular	extracellular	ADJ
ct-9204	86	5	vesicles	vesicle	NOUN
ct-9204	86	6	several	several	ADJ
ct-9204	86	7	methods	method	NOUN
ct-9204	86	8	to	to	PART
ct-9204	86	9	manufacture	manufacture	VERB
ct-9204	86	10	evs	evs	NOUN
ct-9204	86	11	have	have	AUX
ct-9204	86	12	also	also	ADV
ct-9204	86	13	been	be	AUX
ct-9204	86	14	reported	report	VERB
ct-9204	86	15	outside	outside	ADP
ct-9204	86	16	of	of	ADP
ct-9204	86	17	those	those	PRON
ct-9204	86	18	secreted	secrete	VERB
ct-9204	86	19	‘	'	PUNCT
ct-9204	86	20	naturally	naturally	ADV
ct-9204	86	21	’	'	PUNCT
ct-9204	86	22	in	in	ADP
ct-9204	86	23	cell	cell	NOUN
ct-9204	86	24	culture	culture	NOUN
ct-9204	86	25	.	.	PUNCT
ct-9204	87	1	these	these	PRON
ct-9204	87	2	have	have	AUX
ct-9204	87	3	been	be	AUX
ct-9204	87	4	of	of	ADP
ct-9204	87	5	particular	particular	ADJ
ct-9204	87	6	interest	interest	NOUN
ct-9204	87	7	for	for	ADP
ct-9204	87	8	their	their	PRON
ct-9204	87	9	potential	potential	NOUN
ct-9204	87	10	as	as	ADP
ct-9204	87	11	nanoscale	nanoscale	NOUN
ct-9204	87	12	drug	drug	NOUN
ct-9204	87	13	delivery	delivery	NOUN
ct-9204	87	14	systems	system	NOUN
ct-9204	87	15	,	,	PUNCT
ct-9204	87	16	taking	take	VERB
ct-9204	87	17	advantage	advantage	NOUN
ct-9204	87	18	of	of	ADP
ct-9204	87	19	their	their	PRON
ct-9204	87	20	inherent	inherent	ADJ
ct-9204	87	21	cargo	cargo	NOUN
ct-9204	87	22	transfer	transfer	NOUN
ct-9204	87	23	(	(	PUNCT
ct-9204	87	24	reviewed118	reviewed118	ADJ
ct-9204	87	25	-	-	SYM
ct-9204	87	26	121	121	NUM
ct-9204	87	27	)	)	PUNCT
ct-9204	87	28	and	and	CCONJ
ct-9204	87	29	gamete	gamete	NOUN
ct-9204	87	30	/	/	SYM
ct-9204	87	31	embryo	embryo	NOUN
ct-9204	87	32	(	(	PUNCT
ct-9204	87	33	reviewed29	reviewed29	ADJ
ct-9204	87	34	)	)	PUNCT
ct-9204	87	35	abilities	ability	NOUN
ct-9204	87	36	.	.	PUNCT
ct-9204	88	1	most	most	ADJ
ct-9204	88	2	nanovesicles	nanovesicle	NOUN
ct-9204	88	3	or	or	CCONJ
ct-9204	88	4	“	"	PUNCT
ct-9204	88	5	exosome	exosome	PROPN
ct-9204	88	6	mimetics	mimetics	PROPN
ct-9204	88	7	”	"	PUNCT
ct-9204	88	8	have	have	AUX
ct-9204	88	9	been	be	AUX
ct-9204	88	10	produced	produce	VERB
ct-9204	88	11	via	via	ADP
ct-9204	88	12	disruption	disruption	NOUN
ct-9204	88	13	of	of	ADP
ct-9204	88	14	cell	cell	NOUN
ct-9204	88	15	membranes	membrane	NOUN
ct-9204	88	16	.	.	PUNCT
ct-9204	89	1	for	for	ADP
ct-9204	89	2	example	example	NOUN
ct-9204	89	3	,	,	PUNCT
ct-9204	89	4	filter	filter	NOUN
ct-9204	89	5	-	-	PUNCT
ct-9204	89	6	based	base	VERB
ct-9204	89	7	extrusion	extrusion	NOUN
ct-9204	89	8	of	of	ADP
ct-9204	89	9	natural	natural	ADJ
ct-9204	89	10	killer	killer	NOUN
ct-9204	89	11	cells	cell	NOUN
ct-9204	89	12	were	be	AUX
ct-9204	89	13	shown	show	VERB
ct-9204	89	14	to	to	PART
ct-9204	89	15	maintain	maintain	VERB
ct-9204	89	16	antitumor	antitumor	PROPN
ct-9204	89	17	effects	effect	NOUN
ct-9204	89	18	of	of	ADP
ct-9204	89	19	parental	parental	ADJ
ct-9204	89	20	/	/	SYM
ct-9204	89	21	source	source	NOUN
ct-9204	89	22	cells	cell	NOUN
ct-9204	89	23	,	,	PUNCT
ct-9204	89	24	in	in	ADP
ct-9204	89	25	both	both	PRON
ct-9204	89	26	in	in	ADP
ct-9204	89	27	vitro	vitro	X
ct-9204	89	28	and	and	CCONJ
ct-9204	89	29	in	in	ADP
ct-9204	89	30	vivo	vivo	NOUN
ct-9204	89	31	mouse	mouse	NOUN
ct-9204	89	32	models.122	models.122	PROPN
ct-9204	89	33	ev	ev	ADP
ct-9204	89	34	mimetics	mimetic	NOUN
ct-9204	89	35	have	have	AUX
ct-9204	89	36	been	be	AUX
ct-9204	89	37	produced	produce	VERB
ct-9204	89	38	by	by	ADP
ct-9204	89	39	treating	treat	VERB
ct-9204	89	40	cells	cell	NOUN
ct-9204	89	41	with	with	ADP
ct-9204	89	42	cytochalasin	cytochalasin	PROPN
ct-9204	89	43	b	b	PROPN
ct-9204	89	44	,	,	PUNCT
ct-9204	89	45	by	by	ADP
ct-9204	89	46	which	which	PRON
ct-9204	89	47	dissociated	dissociate	VERB
ct-9204	89	48	cell	cell	NOUN
ct-9204	89	49	membranes	membrane	NOUN
ct-9204	89	50	roughly	roughly	ADV
ct-9204	89	51	size	size	NOUN
ct-9204	89	52	of	of	ADP
ct-9204	89	53	mv	mv	PROPN
ct-9204	89	54	can	can	AUX
ct-9204	89	55	be	be	AUX
ct-9204	89	56	obtained.123,124	obtained.123,124	NOUN
ct-9204	89	57	these	these	DET
ct-9204	89	58	‘	'	PUNCT
ct-9204	89	59	nanovesicles	nanovesicle	NOUN
ct-9204	89	60	’	'	PUNCT
ct-9204	89	61	have	have	VERB
ct-9204	89	62	similar	similar	ADJ
ct-9204	89	63	morphology	morphology	NOUN
ct-9204	89	64	to	to	ADP
ct-9204	89	65	natural	natural	ADJ
ct-9204	89	66	evs	evs	NOUN
ct-9204	89	67	(	(	PUNCT
ct-9204	89	68	based	base	VERB
ct-9204	89	69	on	on	ADP
ct-9204	89	70	tem	tem	PROPN
ct-9204	89	71	)	)	PUNCT
ct-9204	89	72	and	and	CCONJ
ct-9204	89	73	reportedly	reportedly	ADV
ct-9204	89	74	have	have	VERB
ct-9204	89	75	similar	similar	ADJ
ct-9204	89	76	content	content	NOUN
ct-9204	89	77	and	and	CCONJ
ct-9204	89	78	functionality	functionality	NOUN
ct-9204	89	79	as	as	SCONJ
ct-9204	89	80	parental	parental	ADJ
ct-9204	89	81	cells.124	cells.124	ADJ
ct-9204	89	82	membrane	membrane	NOUN
ct-9204	89	83	extrusion	extrusion	NOUN
ct-9204	89	84	has	have	AUX
ct-9204	89	85	also	also	ADV
ct-9204	89	86	been	be	AUX
ct-9204	89	87	utilized	utilize	VERB
ct-9204	89	88	to	to	PART
ct-9204	89	89	engineer	engineer	VERB
ct-9204	89	90	‘	'	PUNCT
ct-9204	89	91	hybrid	hybrid	NOUN
ct-9204	89	92	’	'	PUNCT
ct-9204	89	93	evs	evs	NOUN
ct-9204	89	94	.	.	PUNCT
ct-9204	90	1	for	for	ADP
ct-9204	90	2	example	example	NOUN
ct-9204	90	3	,	,	PUNCT
ct-9204	90	4	evs	evs	NOUN
ct-9204	90	5	secreted	secrete	VERB
ct-9204	90	6	from	from	ADP
ct-9204	90	7	3t3	3t3	NUM
ct-9204	90	8	fibroblast	fibroblast	NOUN
ct-9204	90	9	and	and	CCONJ
ct-9204	90	10	a549	a549	PROPN
ct-9204	90	11	tumor	tumor	NOUN
ct-9204	90	12	cell	cell	NOUN
ct-9204	90	13	line	line	NOUN
ct-9204	90	14	were	be	AUX
ct-9204	90	15	fused	fuse	VERB
ct-9204	90	16	with	with	ADP
ct-9204	90	17	synthetic	synthetic	NOUN
ct-9204	90	18	lipids.125	lipids.125	SCONJ
ct-9204	90	19	this	this	DET
ct-9204	90	20	method	method	NOUN
ct-9204	90	21	allowed	allow	VERB
ct-9204	90	22	for	for	ADP
ct-9204	90	23	a	a	DET
ct-9204	90	24	significant	significant	ADJ
ct-9204	90	25	increase	increase	NOUN
ct-9204	90	26	in	in	ADP
ct-9204	90	27	number	number	NOUN
ct-9204	90	28	of	of	ADP
ct-9204	90	29	controlled	control	VERB
ct-9204	90	30	size	size	NOUN
ct-9204	90	31	vesicles	vesicle	NOUN
ct-9204	90	32	compared	compare	VERB
ct-9204	90	33	to	to	PART
ct-9204	90	34	evs	evs	AUX
ct-9204	90	35	purified	purify	VERB
ct-9204	90	36	from	from	ADP
ct-9204	90	37	cell	cell	NOUN
ct-9204	90	38	line	line	NOUN
ct-9204	90	39	secretions	secretion	NOUN
ct-9204	90	40	.	.	PUNCT
ct-9204	91	1	further	far	ADV
ct-9204	91	2	,	,	PUNCT
ct-9204	91	3	engineered	engineer	VERB
ct-9204	91	4	evs	evs	NOUN
ct-9204	91	5	were	be	AUX
ct-9204	91	6	demonstrated	demonstrate	VERB
ct-9204	91	7	to	to	PART
ct-9204	91	8	be	be	AUX
ct-9204	91	9	effective	effective	ADJ
ct-9204	91	10	at	at	ADP
ct-9204	91	11	drug	drug	NOUN
ct-9204	91	12	delivery	delivery	NOUN
ct-9204	91	13	,	,	PUNCT
ct-9204	91	14	as	as	ADP
ct-9204	91	15	small	small	ADJ
ct-9204	91	16	interfering	interfere	VERB
ct-9204	91	17	rna	rna	NOUN
ct-9204	91	18	(	(	PUNCT
ct-9204	91	19	sirna	sirna	PROPN
ct-9204	91	20	)	)	PUNCT
ct-9204	91	21	loaded	load	VERB
ct-9204	91	22	by	by	ADP
ct-9204	91	23	electroporation	electroporation	NOUN
ct-9204	91	24	into	into	ADP
ct-9204	91	25	ev	ev	ADP
ct-9204	91	26	induced	induced	ADJ
ct-9204	91	27	gene	gene	NOUN
ct-9204	91	28	silencing	silence	VERB
ct-9204	91	29	in	in	ADP
ct-9204	91	30	target	target	NOUN
ct-9204	91	31	cells	cell	NOUN
ct-9204	91	32	comparable	comparable	ADJ
ct-9204	91	33	to	to	ADP
ct-9204	91	34	commercially	commercially	ADV
ct-9204	91	35	available	available	ADJ
ct-9204	91	36	kits	kit	NOUN
ct-9204	91	37	.	.	PUNCT
ct-9204	92	1	fusion	fusion	NOUN
ct-9204	92	2	of	of	ADP
ct-9204	92	3	evs	evs	NOUN
ct-9204	92	4	secreted	secrete	VERB
ct-9204	92	5	from	from	ADP
ct-9204	92	6	murine	murine	ADJ
ct-9204	92	7	macrophages	macrophage	NOUN
ct-9204	92	8	with	with	ADP
ct-9204	92	9	engineered	engineer	VERB
ct-9204	92	10	liposomes	liposome	NOUN
ct-9204	92	11	increased	increase	VERB
ct-9204	92	12	yield	yield	NOUN
ct-9204	92	13	while	while	SCONJ
ct-9204	92	14	maintaining	maintain	VERB
ct-9204	92	15	targeted	target	VERB
ct-9204	92	16	binding	bind	VERB
ct-9204	92	17	functionality	functionality	NOUN
ct-9204	92	18	of	of	ADP
ct-9204	92	19	evs.126,127	evs.126,127	NOUN
ct-9204	92	20	these	these	DET
ct-9204	92	21	fusion	fusion	NOUN
ct-9204	92	22	evs	evs	NOUN
ct-9204	92	23	also	also	ADV
ct-9204	92	24	had	have	VERB
ct-9204	92	25	demonstrable	demonstrable	ADJ
ct-9204	92	26	success	success	NOUN
ct-9204	92	27	as	as	ADP
ct-9204	92	28	drug	drug	NOUN
ct-9204	92	29	delivery	delivery	NOUN
ct-9204	92	30	vehicles	vehicle	NOUN
ct-9204	92	31	when	when	SCONJ
ct-9204	92	32	tested	test	VERB
ct-9204	92	33	in	in	ADP
ct-9204	92	34	vitro	vitro	X
ct-9204	92	35	.	.	PUNCT
ct-9204	93	1	getting	get	VERB
ct-9204	93	2	further	far	ADV
ct-9204	93	3	away	away	ADV
ct-9204	93	4	from	from	ADP
ct-9204	93	5	in	in	ADP
ct-9204	93	6	vivo	vivo	NOUN
ct-9204	93	7	derived	derive	VERB
ct-9204	93	8	evs	evs	NOUN
ct-9204	93	9	and	and	CCONJ
ct-9204	93	10	cell	cell	NOUN
ct-9204	93	11	sources	source	NOUN
ct-9204	93	12	,	,	PUNCT
ct-9204	93	13	synthetic	synthetic	ADJ
ct-9204	93	14	vesicles	vesicle	NOUN
ct-9204	93	15	have	have	AUX
ct-9204	93	16	been	be	AUX
ct-9204	93	17	produced	produce	VERB
ct-9204	93	18	(	(	PUNCT
ct-9204	93	19	reviewed92	reviewed92	NOUN
ct-9204	93	20	)	)	PUNCT
ct-9204	93	21	,	,	PUNCT
ct-9204	93	22	including	include	VERB
ct-9204	93	23	liposomes	liposome	NOUN
ct-9204	93	24	(	(	PUNCT
ct-9204	93	25	previously	previously	ADV
ct-9204	93	26	discussed	discuss	VERB
ct-9204	93	27	in	in	ADP
ct-9204	93	28	cryopreservation	cryopreservation	NOUN
ct-9204	93	29	section	section	NOUN
ct-9204	93	30	)	)	PUNCT
ct-9204	93	31	,	,	PUNCT
ct-9204	93	32	composed	compose	VERB
ct-9204	93	33	of	of	ADP
ct-9204	93	34	natural	natural	ADJ
ct-9204	93	35	lipids	lipid	NOUN
ct-9204	93	36	and	and	CCONJ
ct-9204	93	37	fully	fully	ADV
ct-9204	93	38	synthetic	synthetic	ADJ
ct-9204	93	39	‘	'	PUNCT
ct-9204	93	40	polymersomes	polymersome	NOUN
ct-9204	93	41	’	'	PUNCT
ct-9204	93	42	,	,	PUNCT
ct-9204	93	43	composed	compose	VERB
ct-9204	93	44	of	of	ADP
ct-9204	93	45	amphiphilic	amphiphilic	ADJ
ct-9204	93	46	block	block	NOUN
ct-9204	93	47	copolymers.128	copolymers.128	NOUN
ct-9204	93	48	though	though	SCONJ
ct-9204	93	49	cargo	cargo	NOUN
ct-9204	93	50	of	of	ADP
ct-9204	93	51	naturally	naturally	ADV
ct-9204	93	52	secreted	secrete	VERB
ct-9204	93	53	evs	evs	NOUN
ct-9204	93	54	is	be	AUX
ct-9204	93	55	not	not	PART
ct-9204	93	56	replicated	replicate	VERB
ct-9204	93	57	in	in	ADP
ct-9204	93	58	these	these	DET
ct-9204	93	59	manufactured	manufacture	VERB
ct-9204	93	60	vesicles	vesicle	NOUN
ct-9204	93	61	,	,	PUNCT
ct-9204	93	62	above	above	ADP
ct-9204	93	63	studies	study	NOUN
ct-9204	93	64	demonstrated	demonstrate	VERB
ct-9204	93	65	their	their	PRON
ct-9204	93	66	ability	ability	NOUN
ct-9204	93	67	to	to	PART
ct-9204	93	68	be	be	AUX
ct-9204	93	69	loaded	load	VERB
ct-9204	93	70	with	with	ADP
ct-9204	93	71	specific	specific	ADJ
ct-9204	93	72	cargos	cargo	NOUN
ct-9204	93	73	of	of	ADP
ct-9204	93	74	interest	interest	NOUN
ct-9204	93	75	.	.	PUNCT
ct-9204	94	1	as	as	ADP
ct-9204	94	2	a	a	DET
ct-9204	94	3	result	result	NOUN
ct-9204	94	4	,	,	PUNCT
ct-9204	94	5	engineered	engineer	VERB
ct-9204	94	6	evs	evs	NOUN
ct-9204	94	7	have	have	VERB
ct-9204	94	8	potential	potential	NOUN
ct-9204	94	9	for	for	ADP
ct-9204	94	10	drug	drug	NOUN
ct-9204	94	11	delivery	delivery	NOUN
ct-9204	94	12	or	or	CCONJ
ct-9204	94	13	other	other	ADJ
ct-9204	94	14	clinical	clinical	ADJ
ct-9204	94	15	and	and	CCONJ
ct-9204	94	16	art	art	NOUN
ct-9204	94	17	applications	application	NOUN
ct-9204	94	18	.	.	PUNCT
ct-9204	95	1	conclusion	conclusion	NOUN
ct-9204	95	2	extracellular	extracellular	ADJ
ct-9204	95	3	vesicle	vesicle	NOUN
ct-9204	95	4	research	research	NOUN
ct-9204	95	5	represents	represent	VERB
ct-9204	95	6	a	a	DET
ct-9204	95	7	rapidly	rapidly	ADV
ct-9204	95	8	evolving	evolve	VERB
ct-9204	95	9	field	field	NOUN
ct-9204	95	10	with	with	ADP
ct-9204	95	11	diverse	diverse	ADJ
ct-9204	95	12	potential	potential	ADJ
ct-9204	95	13	clinical	clinical	ADJ
ct-9204	95	14	applications	application	NOUN
ct-9204	95	15	.	.	PUNCT
ct-9204	96	1	although	although	SCONJ
ct-9204	96	2	work	work	NOUN
ct-9204	96	3	on	on	ADP
ct-9204	96	4	reproductive	reproductive	ADJ
ct-9204	96	5	evs	evs	NOUN
ct-9204	96	6	is	be	AUX
ct-9204	96	7	relatively	relatively	ADV
ct-9204	96	8	new	new	ADJ
ct-9204	96	9	,	,	PUNCT
ct-9204	96	10	epididymosomes	epididymosome	NOUN
ct-9204	96	11	,	,	PUNCT
ct-9204	96	12	prostasomes	prostasome	NOUN
ct-9204	96	13	,	,	PUNCT
ct-9204	96	14	vaginasomes	vaginasome	NOUN
ct-9204	96	15	,	,	PUNCT
ct-9204	96	16	uterosomes	uterosome	NOUN
ct-9204	96	17	and	and	CCONJ
ct-9204	96	18	oviductosomes	oviductosome	NOUN
ct-9204	96	19	have	have	AUX
ct-9204	96	20	been	be	AUX
ct-9204	96	21	characterized	characterize	VERB
ct-9204	96	22	in	in	ADP
ct-9204	96	23	numerous	numerous	ADJ
ct-9204	96	24	studies	study	NOUN
ct-9204	96	25	.	.	PUNCT
ct-9204	97	1	this	this	DET
ct-9204	97	2	interest	interest	NOUN
ct-9204	97	3	is	be	AUX
ct-9204	97	4	owed	owe	VERB
ct-9204	97	5	in	in	ADP
ct-9204	97	6	no	no	DET
ct-9204	97	7	small	small	ADJ
ct-9204	97	8	part	part	NOUN
ct-9204	97	9	to	to	ADP
ct-9204	97	10	important	important	ADJ
ct-9204	97	11	effects	effect	NOUN
ct-9204	97	12	observed	observe	VERB
ct-9204	97	13	on	on	ADP
ct-9204	97	14	gamete	gamete	ADJ
ct-9204	97	15	maturation	maturation	NOUN
ct-9204	97	16	and	and	CCONJ
ct-9204	97	17	function	function	NOUN
ct-9204	97	18	observed	observe	VERB
ct-9204	97	19	thus	thus	ADV
ct-9204	97	20	far	far	ADV
ct-9204	97	21	.	.	PUNCT
ct-9204	98	1	substantially	substantially	ADV
ct-9204	98	2	more	more	ADJ
ct-9204	98	3	work	work	NOUN
ct-9204	98	4	is	be	AUX
ct-9204	98	5	needed	need	VERB
ct-9204	98	6	to	to	PART
ct-9204	98	7	fully	fully	ADV
ct-9204	98	8	understand	understand	VERB
ct-9204	98	9	biogenesis	biogenesis	NOUN
ct-9204	98	10	,	,	PUNCT
ct-9204	98	11	uptake	uptake	ADJ
ct-9204	98	12	,	,	PUNCT
ct-9204	98	13	and	and	CCONJ
ct-9204	98	14	downstream	downstream	ADJ
ct-9204	98	15	effects	effect	NOUN
ct-9204	98	16	of	of	ADP
ct-9204	98	17	varying	vary	VERB
ct-9204	98	18	ev	ev	VERB
ct-9204	98	19	,	,	PUNCT
ct-9204	98	20	particularly	particularly	ADV
ct-9204	98	21	within	within	ADP
ct-9204	98	22	context	context	NOUN
ct-9204	98	23	of	of	ADP
ct-9204	98	24	reproductive	reproductive	ADJ
ct-9204	98	25	tract	tract	NOUN
ct-9204	98	26	.	.	PUNCT
ct-9204	99	1	however	however	ADV
ct-9204	99	2	,	,	PUNCT
ct-9204	99	3	if	if	SCONJ
ct-9204	99	4	new	new	ADJ
ct-9204	99	5	methods	method	NOUN
ct-9204	99	6	for	for	ADP
ct-9204	99	7	in	in	ADP
ct-9204	99	8	vitro	vitro	X
ct-9204	99	9	production	production	NOUN
ct-9204	99	10	can	can	AUX
ct-9204	99	11	consistently	consistently	ADV
ct-9204	99	12	generate	generate	VERB
ct-9204	99	13	high	high	ADJ
ct-9204	99	14	quality	quality	NOUN
ct-9204	99	15	and	and	CCONJ
ct-9204	99	16	quantity	quantity	NOUN
ct-9204	99	17	vesicles	vesicle	NOUN
ct-9204	99	18	,	,	PUNCT
ct-9204	99	19	there	there	PRON
ct-9204	99	20	is	be	VERB
ct-9204	99	21	broad	broad	ADJ
ct-9204	99	22	clinical	clinical	ADJ
ct-9204	99	23	potential	potential	NOUN
ct-9204	99	24	of	of	ADP
ct-9204	99	25	evs	evs	NOUN
ct-9204	99	26	in	in	ADP
ct-9204	99	27	assisted	assist	VERB
ct-9204	99	28	reproduction	reproduction	NOUN
ct-9204	99	29	.	.	PUNCT
ct-9204	100	1	clinical	clinical	ADJ
ct-9204	100	2	theriogenology	theriogenology	NOUN
ct-9204	100	3	•	•	NOUN
ct-9204	100	4	volume	volume	NOUN
ct-9204	100	5	12	12	NUM
ct-9204	100	6	number	number	NOUN
ct-9204	100	7	2	2	NUM
ct-9204	100	8	•	•	NOUN
ct-9204	100	9	june	june	PROPN
ct-9204	100	10	202096	202096	NUM
ct-9204	100	11	conflict	conflict	NOUN
ct-9204	100	12	of	of	ADP
ct-9204	100	13	interest	interest	NOUN
ct-9204	100	14	there	there	PRON
ct-9204	100	15	are	be	VERB
ct-9204	100	16	no	no	DET
ct-9204	100	17	conflicts	conflict	NOUN
ct-9204	100	18	of	of	ADP
ct-9204	100	19	interest	interest	NOUN
ct-9204	100	20	to	to	PART
ct-9204	100	21	declare	declare	VERB
ct-9204	100	22	.	.	PUNCT
ct-9204	101	1	acknowledgement	acknowledgement	PROPN
ct-9204	101	2	authors	author	NOUN
ct-9204	101	3	thank	thank	VERB
ct-9204	101	4	national	national	PROPN
ct-9204	101	5	institute	institute	PROPN
ct-9204	101	6	of	of	ADP
ct-9204	101	7	health	health	PROPN
ct-9204	101	8	1f32hd090854	1f32hd090854	PROPN
ct-9204	101	9	-	-	SYM
ct-9204	101	10	01a1	01a1	NUM
ct-9204	101	11	(	(	PUNCT
ct-9204	101	12	j.n	j.n	PROPN
ct-9204	101	13	.	.	PROPN
ct-9204	101	14	)	)	PUNCT
ct-9204	102	1	and	and	CCONJ
ct-9204	102	2	smithsonian	smithsonian	ADJ
ct-9204	102	3	institution	institution	NOUN
ct-9204	102	4	for	for	ADP
ct-9204	102	5	support	support	NOUN
ct-9204	102	6	.	.	PUNCT
ct-9204	103	1	references	reference	NOUN
ct-9204	103	2	1	1	NUM
ct-9204	103	3	.	.	PUNCT
ct-9204	104	1	doyle	doyle	PROPN
ct-9204	104	2	lm	lm	PROPN
ct-9204	104	3	,	,	PUNCT
ct-9204	104	4	wang	wang	PROPN
ct-9204	104	5	mz	mz	PROPN
ct-9204	104	6	:	:	PUNCT
ct-9204	104	7	overview	overview	NOUN
ct-9204	104	8	of	of	ADP
ct-9204	104	9	extracellular	extracellular	ADJ
ct-9204	104	10	vesicles	vesicle	NOUN
ct-9204	104	11	,	,	PUNCT
ct-9204	104	12	their	their	PRON
ct-9204	104	13	origin	origin	NOUN
ct-9204	104	14	,	,	PUNCT
ct-9204	104	15	composition	composition	NOUN
ct-9204	104	16	,	,	PUNCT
ct-9204	104	17	purpose	purpose	NOUN
ct-9204	104	18	,	,	PUNCT
ct-9204	104	19	and	and	CCONJ
ct-9204	104	20	methods	method	NOUN
ct-9204	104	21	for	for	ADP
ct-9204	104	22	exosome	exosome	NOUN
ct-9204	104	23	isolation	isolation	NOUN
ct-9204	104	24	and	and	CCONJ
ct-9204	104	25	analysis	analysis	NOUN
ct-9204	104	26	.	.	PUNCT
ct-9204	105	1	cells	cell	NOUN
ct-9204	105	2	2019;8:727	2019;8:727	NUM
ct-9204	105	3	-	-	SYM
ct-9204	105	4	751	751	NUM
ct-9204	105	5	.	.	NOUN
ct-9204	106	1	2	2	NUM
ct-9204	106	2	.	.	NUM
ct-9204	106	3	abels	abel	NOUN
ct-9204	106	4	er	er	INTJ
ct-9204	106	5	,	,	PUNCT
ct-9204	106	6	breakefield	breakefield	PROPN
ct-9204	106	7	xo	xo	PROPN
ct-9204	106	8	:	:	PUNCT
ct-9204	106	9	introduction	introduction	NOUN
ct-9204	106	10	to	to	ADP
ct-9204	106	11	extracellular	extracellular	ADJ
ct-9204	106	12	vesicles	vesicle	NOUN
ct-9204	106	13	:	:	PUNCT
ct-9204	106	14	biogenesis	biogenesis	NOUN
ct-9204	106	15	,	,	PUNCT
ct-9204	106	16	rna	rna	NOUN
ct-9204	106	17	cargo	cargo	NOUN
ct-9204	106	18	selection	selection	NOUN
ct-9204	106	19	,	,	PUNCT
ct-9204	106	20	content	content	NOUN
ct-9204	106	21	,	,	PUNCT
ct-9204	106	22	release	release	NOUN
ct-9204	106	23	,	,	PUNCT
ct-9204	106	24	and	and	CCONJ
ct-9204	106	25	uptake	uptake	ADJ
ct-9204	106	26	.	.	PUNCT
ct-9204	107	1	cell	cell	NOUN
ct-9204	107	2	mol	mol	ADP
ct-9204	107	3	neurobiol	neurobiol	PROPN
ct-9204	107	4	2016;36:301	2016;36:301	NUM
ct-9204	107	5	-	-	SYM
ct-9204	107	6	312	312	NUM
ct-9204	107	7	.	.	PUNCT
ct-9204	108	1	3	3	X
ct-9204	108	2	.	.	X
ct-9204	108	3	wickman	wickman	PROPN
ct-9204	108	4	g	g	PROPN
ct-9204	108	5	,	,	PUNCT
ct-9204	108	6	julian	julian	PROPN
ct-9204	108	7	l	l	PROPN
ct-9204	108	8	,	,	PUNCT
ct-9204	108	9	olson	olson	NOUN
ct-9204	108	10	m	m	PROPN
ct-9204	108	11	:	:	PUNCT
ct-9204	108	12	how	how	SCONJ
ct-9204	108	13	apoptotic	apoptotic	ADJ
ct-9204	108	14	cells	cell	NOUN
ct-9204	108	15	aid	aid	VERB
ct-9204	108	16	in	in	ADP
ct-9204	108	17	the	the	DET
ct-9204	108	18	removal	removal	NOUN
ct-9204	108	19	of	of	ADP
ct-9204	108	20	their	their	PRON
ct-9204	108	21	own	own	ADJ
ct-9204	108	22	cold	cold	ADJ
ct-9204	108	23	dead	dead	ADJ
ct-9204	108	24	bodies	body	NOUN
ct-9204	108	25	.	.	PUNCT
ct-9204	109	1	cell	cell	NOUN
ct-9204	109	2	death	death	NOUN
ct-9204	109	3	differ	differ	VERB
ct-9204	109	4	2012;19:735	2012;19:735	NOUN
ct-9204	109	5	-	-	SYM
ct-9204	109	6	742	742	NUM
ct-9204	109	7	.	.	NOUN
ct-9204	110	1	4	4	NUM
ct-9204	110	2	.	.	X
ct-9204	110	3	zaborowski	zaborowski	PROPN
ct-9204	110	4	mp	mp	PROPN
ct-9204	110	5	,	,	PUNCT
ct-9204	110	6	balaj	balaj	NOUN
ct-9204	110	7	l	l	NOUN
ct-9204	110	8	,	,	PUNCT
ct-9204	110	9	breakefield	breakefield	PROPN
ct-9204	110	10	xo	xo	PROPN
ct-9204	110	11	,	,	PUNCT
ct-9204	110	12	et	et	PROPN
ct-9204	110	13	al	al	PROPN
ct-9204	110	14	:	:	PUNCT
ct-9204	110	15	extracellular	extracellular	ADJ
ct-9204	110	16	vesicles	vesicle	NOUN
ct-9204	110	17	:	:	PUNCT
ct-9204	110	18	composition	composition	NOUN
ct-9204	110	19	,	,	PUNCT
ct-9204	110	20	biological	biological	ADJ
ct-9204	110	21	relevance	relevance	NOUN
ct-9204	110	22	,	,	PUNCT
ct-9204	110	23	and	and	CCONJ
ct-9204	110	24	methods	method	NOUN
ct-9204	110	25	of	of	ADP
ct-9204	110	26	study	study	NOUN
ct-9204	110	27	.	.	PUNCT
ct-9204	111	1	bioscience	bioscience	NOUN
ct-9204	111	2	2015;65:783	2015;65:783	PROPN
ct-9204	111	3	-	-	NOUN
ct-9204	111	4	797	797	NUM
ct-9204	111	5	.	.	PUNCT
ct-9204	112	1	5	5	NUM
ct-9204	112	2	.	.	NUM
ct-9204	112	3	willms	willm	NOUN
ct-9204	112	4	e	e	NOUN
ct-9204	112	5	,	,	PUNCT
ct-9204	112	6	cabañas	cabañas	NOUN
ct-9204	112	7	c	c	PROPN
ct-9204	112	8	,	,	PUNCT
ct-9204	112	9	mäger	mäger	PROPN
ct-9204	113	1	i	i	PRON
ct-9204	113	2	,	,	PUNCT
ct-9204	113	3	et	et	PROPN
ct-9204	113	4	al	al	PROPN
ct-9204	113	5	:	:	PUNCT
ct-9204	113	6	extracellular	extracellular	ADJ
ct-9204	113	7	vesicle	vesicle	NOUN
ct-9204	113	8	heterogeneity	heterogeneity	NOUN
ct-9204	113	9	:	:	PUNCT
ct-9204	113	10	subpopulations	subpopulation	NOUN
ct-9204	113	11	,	,	PUNCT
ct-9204	113	12	isolation	isolation	NOUN
ct-9204	113	13	techniques	technique	NOUN
ct-9204	113	14	,	,	PUNCT
ct-9204	113	15	and	and	CCONJ
ct-9204	113	16	diverse	diverse	ADJ
ct-9204	113	17	functions	function	NOUN
ct-9204	113	18	in	in	ADP
ct-9204	113	19	cancer	cancer	NOUN
ct-9204	113	20	progression	progression	NOUN
ct-9204	113	21	.	.	PUNCT
ct-9204	114	1	front	front	ADJ
ct-9204	114	2	immunol	immunol	NOUN
ct-9204	114	3	2018;9:738	2018;9:738	PROPN
ct-9204	114	4	.	.	PROPN
ct-9204	115	1	6	6	NUM
ct-9204	115	2	.	.	X
ct-9204	115	3	gudbergsson	gudbergsson	PROPN
ct-9204	115	4	jm	jm	PROPN
ct-9204	115	5	,	,	PUNCT
ct-9204	115	6	johnsen	johnsen	PROPN
ct-9204	115	7	kb	kb	PROPN
ct-9204	115	8	,	,	PUNCT
ct-9204	115	9	skov	skov	PROPN
ct-9204	115	10	mn	mn	PROPN
ct-9204	115	11	,	,	PUNCT
ct-9204	115	12	et	et	PROPN
ct-9204	115	13	al	al	PROPN
ct-9204	115	14	:	:	PUNCT
ct-9204	115	15	systematic	systematic	ADJ
ct-9204	115	16	review	review	NOUN
ct-9204	115	17	of	of	ADP
ct-9204	115	18	factors	factor	NOUN
ct-9204	115	19	influencing	influence	VERB
ct-9204	115	20	extracellular	extracellular	ADJ
ct-9204	115	21	vesicle	vesicle	NOUN
ct-9204	115	22	yield	yield	NOUN
ct-9204	115	23	from	from	ADP
ct-9204	115	24	cell	cell	NOUN
ct-9204	115	25	cultures	culture	NOUN
ct-9204	115	26	.	.	PUNCT
ct-9204	116	1	cytotechnology	cytotechnology	NOUN
ct-9204	116	2	2016;68:579	2016;68:579	PROPN
ct-9204	116	3	-	-	SYM
ct-9204	116	4	592	592	NUM
ct-9204	116	5	.	.	PUNCT
ct-9204	117	1	7	7	X
ct-9204	117	2	.	.	X
ct-9204	117	3	zhang	zhang	PROPN
ct-9204	117	4	z	z	PROPN
ct-9204	117	5	,	,	PUNCT
ct-9204	117	6	wang	wang	PROPN
ct-9204	117	7	c	c	PROPN
ct-9204	117	8	,	,	PUNCT
ct-9204	117	9	li	li	PROPN
ct-9204	117	10	t	t	PROPN
ct-9204	117	11	,	,	PUNCT
ct-9204	117	12	et	et	PROPN
ct-9204	117	13	al	al	PROPN
ct-9204	117	14	:	:	PUNCT
ct-9204	117	15	comparison	comparison	NOUN
ct-9204	117	16	of	of	ADP
ct-9204	117	17	ultracentrifugation	ultracentrifugation	NOUN
ct-9204	117	18	and	and	CCONJ
ct-9204	117	19	density	density	NOUN
ct-9204	117	20	gradient	gradient	NOUN
ct-9204	117	21	separation	separation	NOUN
ct-9204	117	22	methods	method	NOUN
ct-9204	117	23	for	for	ADP
ct-9204	117	24	isolating	isolate	VERB
ct-9204	117	25	tca8113	tca8113	NOUN
ct-9204	117	26	human	human	PROPN
ct-9204	117	27	tongue	tongue	NOUN
ct-9204	117	28	cancer	cancer	NOUN
ct-9204	117	29	cell	cell	NOUN
ct-9204	117	30	line‑derived	line‑derive	VERB
ct-9204	117	31	exosomes	exosome	NOUN
ct-9204	117	32	.	.	PUNCT
ct-9204	118	1	oncol	oncol	ADJ
ct-9204	118	2	lett	lett	PROPN
ct-9204	118	3	2014;8:1701	2014;8:1701	PROPN
ct-9204	118	4	-	-	SYM
ct-9204	118	5	1706	1706	NUM
ct-9204	118	6	.	.	PUNCT
ct-9204	118	7	8	8	NUM
ct-9204	118	8	.	.	X
ct-9204	119	1	davis	davis	PROPN
ct-9204	119	2	cn	cn	PROPN
ct-9204	119	3	,	,	PUNCT
ct-9204	119	4	phillips	phillips	PROPN
ct-9204	119	5	h	h	NOUN
ct-9204	119	6	,	,	PUNCT
ct-9204	119	7	tomes	tomes	PROPN
ct-9204	119	8	jj	jj	PROPN
ct-9204	119	9	,	,	PUNCT
ct-9204	119	10	et	et	PROPN
ct-9204	119	11	al	al	PROPN
ct-9204	119	12	:	:	PUNCT
ct-9204	119	13	the	the	DET
ct-9204	119	14	importance	importance	NOUN
ct-9204	119	15	of	of	ADP
ct-9204	119	16	extracellular	extracellular	ADJ
ct-9204	119	17	vesicle	vesicle	NOUN
ct-9204	119	18	purification	purification	NOUN
ct-9204	119	19	for	for	ADP
ct-9204	119	20	downstream	downstream	ADJ
ct-9204	119	21	analysis	analysis	NOUN
ct-9204	119	22	:	:	PUNCT
ct-9204	119	23	a	a	DET
ct-9204	119	24	comparison	comparison	NOUN
ct-9204	119	25	of	of	ADP
ct-9204	119	26	differential	differential	ADJ
ct-9204	119	27	centrifugation	centrifugation	NOUN
ct-9204	119	28	and	and	CCONJ
ct-9204	119	29	size	size	NOUN
ct-9204	119	30	exclusion	exclusion	NOUN
ct-9204	119	31	chromatography	chromatography	NOUN
ct-9204	119	32	for	for	ADP
ct-9204	119	33	helminth	helminth	NOUN
ct-9204	119	34	pathogens	pathogen	NOUN
ct-9204	119	35	.	.	PUNCT
ct-9204	120	1	plos	plos	PROPN
ct-9204	120	2	neglect	neglect	NOUN
ct-9204	120	3	trop	trop	X
ct-9204	120	4	d	d	PROPN
ct-9204	120	5	2019;13	2019;13	NUM
ct-9204	120	6	:	:	PUNCT
ct-9204	120	7	e0007191	e0007191	PROPN
ct-9204	120	8	.	.	PROPN
ct-9204	121	1	9	9	NUM
ct-9204	121	2	.	.	X
ct-9204	121	3	nordin	nordin	PROPN
ct-9204	121	4	jz	jz	PROPN
ct-9204	121	5	,	,	PUNCT
ct-9204	121	6	lee	lee	PROPN
ct-9204	121	7	y	y	PROPN
ct-9204	121	8	,	,	PUNCT
ct-9204	121	9	vader	vader	NOUN
ct-9204	121	10	p	p	NOUN
ct-9204	121	11	,	,	PUNCT
ct-9204	121	12	et	et	PROPN
ct-9204	121	13	al	al	PROPN
ct-9204	121	14	:	:	PUNCT
ct-9204	121	15	ultrafiltration	ultrafiltration	NOUN
ct-9204	121	16	with	with	ADP
ct-9204	121	17	size	size	NOUN
ct-9204	121	18	-	-	PUNCT
ct-9204	121	19	exclusion	exclusion	NOUN
ct-9204	121	20	liquid	liquid	ADJ
ct-9204	121	21	chromatography	chromatography	NOUN
ct-9204	121	22	for	for	ADP
ct-9204	121	23	high	high	ADJ
ct-9204	121	24	yield	yield	NOUN
ct-9204	121	25	isolation	isolation	NOUN
ct-9204	121	26	of	of	ADP
ct-9204	121	27	extracellular	extracellular	ADJ
ct-9204	121	28	vesicles	vesicle	NOUN
ct-9204	121	29	preserving	preserve	VERB
ct-9204	121	30	intact	intact	ADJ
ct-9204	121	31	biophysical	biophysical	ADJ
ct-9204	121	32	and	and	CCONJ
ct-9204	121	33	functional	functional	ADJ
ct-9204	121	34	properties	property	NOUN
ct-9204	121	35	.	.	PUNCT
ct-9204	122	1	nanomed	nanome	VERB
ct-9204	122	2	-	-	PUNCT
ct-9204	122	3	nanotechnol	nanotechnol	NOUN
ct-9204	122	4	2015;11:879	2015;11:879	PROPN
ct-9204	122	5	-	-	PUNCT
ct-9204	122	6	883	883	NUM
ct-9204	122	7	.	.	NOUN
ct-9204	122	8	10	10	NUM
ct-9204	122	9	.	.	PUNCT
ct-9204	123	1	heinemann	heinemann	PROPN
ct-9204	123	2	ml	ml	PROPN
ct-9204	123	3	,	,	PUNCT
ct-9204	123	4	ilmer	ilmer	PROPN
ct-9204	123	5	m	m	PROPN
ct-9204	123	6	,	,	PUNCT
ct-9204	123	7	silva	silva	PROPN
ct-9204	123	8	lp	lp	PROPN
ct-9204	123	9	,	,	PUNCT
ct-9204	123	10	et	et	PROPN
ct-9204	123	11	al	al	PROPN
ct-9204	123	12	:	:	PUNCT
ct-9204	123	13	benchtop	benchtop	NOUN
ct-9204	123	14	isolation	isolation	NOUN
ct-9204	123	15	and	and	CCONJ
ct-9204	123	16	characterization	characterization	NOUN
ct-9204	123	17	of	of	ADP
ct-9204	123	18	functional	functional	ADJ
ct-9204	123	19	exosomes	exosome	NOUN
ct-9204	123	20	by	by	ADP
ct-9204	123	21	sequential	sequential	ADJ
ct-9204	123	22	filtration	filtration	NOUN
ct-9204	123	23	.	.	PUNCT
ct-9204	124	1	j	j	PROPN
ct-9204	124	2	chromatogr	chromatogr	VERB
ct-9204	124	3	a	a	DET
ct-9204	124	4	2014;1371:125	2014;1371:125	NUM
ct-9204	124	5	-	-	SYM
ct-9204	124	6	135	135	NUM
ct-9204	124	7	.	.	PUNCT
ct-9204	125	1	11	11	NUM
ct-9204	125	2	.	.	PUNCT
ct-9204	126	1	niu	niu	PROPN
ct-9204	126	2	z	z	PROPN
ct-9204	126	3	,	,	PUNCT
ct-9204	126	4	pang	pang	PROPN
ct-9204	126	5	rt	rt	PROPN
ct-9204	126	6	,	,	PUNCT
ct-9204	126	7	liu	liu	PROPN
ct-9204	126	8	w	w	PROPN
ct-9204	126	9	,	,	PUNCT
ct-9204	126	10	et	et	PROPN
ct-9204	126	11	al	al	PROPN
ct-9204	126	12	:	:	PUNCT
ct-9204	126	13	polymer	polymer	NOUN
ct-9204	126	14	-	-	PUNCT
ct-9204	126	15	based	base	VERB
ct-9204	126	16	precipitation	precipitation	NOUN
ct-9204	126	17	preserves	preserve	VERB
ct-9204	126	18	biological	biological	ADJ
ct-9204	126	19	activities	activity	NOUN
ct-9204	126	20	of	of	ADP
ct-9204	126	21	extracellular	extracellular	ADJ
ct-9204	126	22	vesicles	vesicle	NOUN
ct-9204	126	23	from	from	ADP
ct-9204	126	24	an	an	DET
ct-9204	126	25	endometrial	endometrial	ADJ
ct-9204	126	26	cell	cell	NOUN
ct-9204	126	27	line	line	NOUN
ct-9204	126	28	.	.	PUNCT
ct-9204	127	1	plos	plos	PROPN
ct-9204	127	2	one	one	NUM
ct-9204	127	3	2017;12	2017;12	NOUN
ct-9204	127	4	:	:	PUNCT
ct-9204	127	5	e0186534	e0186534	PROPN
ct-9204	127	6	.	.	PUNCT
ct-9204	127	7	12	12	NUM
ct-9204	127	8	.	.	PUNCT
ct-9204	128	1	györgy	györgy	PROPN
ct-9204	128	2	b	b	PROPN
ct-9204	128	3	,	,	PUNCT
ct-9204	128	4	módos	módo	NOUN
ct-9204	128	5	k	k	NOUN
ct-9204	128	6	,	,	PUNCT
ct-9204	128	7	pállinger	pállinger	NOUN
ct-9204	128	8	é	é	PROPN
ct-9204	128	9	,	,	PUNCT
ct-9204	128	10	et	et	PROPN
ct-9204	128	11	al	al	PROPN
ct-9204	128	12	:	:	PUNCT
ct-9204	128	13	detection	detection	NOUN
ct-9204	128	14	and	and	CCONJ
ct-9204	128	15	isolation	isolation	NOUN
ct-9204	128	16	of	of	ADP
ct-9204	128	17	cell	cell	NOUN
ct-9204	128	18	-	-	PUNCT
ct-9204	128	19	derived	derive	VERB
ct-9204	128	20	microparticles	microparticle	NOUN
ct-9204	128	21	are	be	AUX
ct-9204	128	22	compromised	compromise	VERB
ct-9204	128	23	by	by	ADP
ct-9204	128	24	protein	protein	NOUN
ct-9204	128	25	complexes	complex	NOUN
ct-9204	128	26	resulting	result	VERB
ct-9204	128	27	from	from	ADP
ct-9204	128	28	shared	share	VERB
ct-9204	128	29	biophysical	biophysical	ADJ
ct-9204	128	30	parameters	parameter	NOUN
ct-9204	128	31	.	.	PUNCT
ct-9204	129	1	blood	blood	NOUN
ct-9204	129	2	2011;117	2011;117	NUM
ct-9204	129	3	:	:	PUNCT
ct-9204	129	4	e39	e39	NOUN
ct-9204	129	5	-	-	PUNCT
ct-9204	129	6	e48	e48	NOUN
ct-9204	129	7	.	.	PUNCT
ct-9204	130	1	13	13	NUM
ct-9204	130	2	.	.	X
ct-9204	131	1	colombo	colombo	PROPN
ct-9204	131	2	m	m	PROPN
ct-9204	131	3	,	,	PUNCT
ct-9204	131	4	moita	moita	PROPN
ct-9204	131	5	c	c	X
ct-9204	131	6	,	,	PUNCT
ct-9204	131	7	van	van	PROPN
ct-9204	131	8	niel	niel	PROPN
ct-9204	131	9	g	g	PROPN
ct-9204	131	10	,	,	PUNCT
ct-9204	131	11	et	et	PROPN
ct-9204	131	12	al	al	PROPN
ct-9204	131	13	:	:	PUNCT
ct-9204	131	14	analysis	analysis	NOUN
ct-9204	131	15	of	of	ADP
ct-9204	131	16	escrt	escrt	ADJ
ct-9204	131	17	functions	function	NOUN
ct-9204	131	18	in	in	ADP
ct-9204	131	19	exosome	exosome	ADJ
ct-9204	131	20	biogenesis	biogenesis	NOUN
ct-9204	131	21	,	,	PUNCT
ct-9204	131	22	composition	composition	NOUN
ct-9204	131	23	and	and	CCONJ
ct-9204	131	24	secretion	secretion	NOUN
ct-9204	131	25	highlights	highlight	NOUN
ct-9204	131	26	the	the	DET
ct-9204	131	27	heterogeneity	heterogeneity	NOUN
ct-9204	131	28	of	of	ADP
ct-9204	131	29	extracellular	extracellular	ADJ
ct-9204	131	30	vesicles	vesicle	NOUN
ct-9204	131	31	.	.	PUNCT
ct-9204	132	1	j	j	PROPN
ct-9204	132	2	cell	cell	NOUN
ct-9204	132	3	sci	sci	PROPN
ct-9204	132	4	2013;126:5553	2013;126:5553	PROPN
ct-9204	132	5	-	-	SYM
ct-9204	132	6	5565	5565	NUM
ct-9204	132	7	.	.	PUNCT
ct-9204	133	1	14	14	NUM
ct-9204	133	2	.	.	PUNCT
ct-9204	134	1	termini	termini	PROPN
ct-9204	134	2	cm	cm	PROPN
ct-9204	134	3	,	,	PUNCT
ct-9204	134	4	gillette	gillette	PROPN
ct-9204	134	5	jm	jm	PROPN
ct-9204	134	6	:	:	PUNCT
ct-9204	134	7	tetraspanins	tetraspanin	NOUN
ct-9204	134	8	function	function	VERB
ct-9204	134	9	as	as	ADP
ct-9204	134	10	regulators	regulator	NOUN
ct-9204	134	11	of	of	ADP
ct-9204	134	12	cellular	cellular	ADJ
ct-9204	134	13	signaling	signaling	NOUN
ct-9204	134	14	.	.	PUNCT
ct-9204	135	1	front	front	ADJ
ct-9204	135	2	cell	cell	NOUN
ct-9204	135	3	dev	dev	PROPN
ct-9204	135	4	biol	biol	PROPN
ct-9204	135	5	2017;5:34	2017;5:34	PROPN
ct-9204	135	6	-	-	PUNCT
ct-9204	135	7	34	34	NUM
ct-9204	135	8	.	.	NOUN
ct-9204	135	9	15	15	NUM
ct-9204	135	10	.	.	PUNCT
ct-9204	136	1	gastpar	gastpar	NOUN
ct-9204	136	2	r	r	PROPN
ct-9204	136	3	,	,	PUNCT
ct-9204	136	4	gehrmann	gehrmann	PROPN
ct-9204	136	5	m	m	PROPN
ct-9204	136	6	,	,	PUNCT
ct-9204	136	7	bausero	bausero	PROPN
ct-9204	136	8	ma	ma	PROPN
ct-9204	136	9	,	,	PUNCT
ct-9204	136	10	et	et	PROPN
ct-9204	136	11	al	al	PROPN
ct-9204	136	12	:	:	PUNCT
ct-9204	136	13	heat	heat	NOUN
ct-9204	136	14	shock	shock	NOUN
ct-9204	136	15	protein	protein	NOUN
ct-9204	136	16	70	70	NUM
ct-9204	136	17	surface	surface	NOUN
ct-9204	136	18	-	-	PUNCT
ct-9204	136	19	positive	positive	ADJ
ct-9204	136	20	tumor	tumor	NOUN
ct-9204	136	21	exosomes	exosome	NOUN
ct-9204	136	22	stimulate	stimulate	VERB
ct-9204	136	23	migratory	migratory	ADJ
ct-9204	136	24	and	and	CCONJ
ct-9204	136	25	cytolytic	cytolytic	ADJ
ct-9204	136	26	activity	activity	NOUN
ct-9204	136	27	of	of	ADP
ct-9204	136	28	natural	natural	ADJ
ct-9204	136	29	killer	killer	NOUN
ct-9204	136	30	cells	cell	NOUN
ct-9204	136	31	.	.	PUNCT
ct-9204	137	1	cancer	cancer	NOUN
ct-9204	137	2	res	re	VERB
ct-9204	137	3	2005;65:5238	2005;65:5238	NUM
ct-9204	137	4	-	-	SYM
ct-9204	137	5	5247	5247	NUM
ct-9204	137	6	.	.	PUNCT
ct-9204	138	1	16	16	NUM
ct-9204	138	2	.	.	PUNCT
ct-9204	138	3	théry	théry	PROPN
ct-9204	138	4	c	c	NOUN
ct-9204	138	5	,	,	PUNCT
ct-9204	138	6	regnault	regnault	VERB
ct-9204	138	7	a	a	PRON
ct-9204	138	8	,	,	PUNCT
ct-9204	138	9	garin	garin	PROPN
ct-9204	138	10	j	j	PROPN
ct-9204	138	11	,	,	PUNCT
ct-9204	138	12	et	et	PROPN
ct-9204	138	13	al	al	PROPN
ct-9204	138	14	:	:	PUNCT
ct-9204	138	15	molecular	molecular	ADJ
ct-9204	138	16	characterization	characterization	NOUN
ct-9204	138	17	of	of	ADP
ct-9204	138	18	dendritic	dendritic	ADJ
ct-9204	138	19	cell	cell	NOUN
ct-9204	138	20	-	-	PUNCT
ct-9204	138	21	derived	derive	VERB
ct-9204	138	22	exosomes	exosome	NOUN
ct-9204	138	23	:	:	PUNCT
ct-9204	138	24	selective	selective	ADJ
ct-9204	138	25	accumulation	accumulation	NOUN
ct-9204	138	26	of	of	ADP
ct-9204	138	27	the	the	DET
ct-9204	138	28	heat	heat	NOUN
ct-9204	138	29	shock	shock	NOUN
ct-9204	138	30	protein	protein	NOUN
ct-9204	138	31	hsc73	hsc73	NOUN
ct-9204	138	32	.	.	PUNCT
ct-9204	139	1	j	j	PROPN
ct-9204	139	2	cell	cell	NOUN
ct-9204	139	3	biol	biol	NOUN
ct-9204	139	4	1999;147:599	1999;147:599	NUM
ct-9204	139	5	-	-	SYM
ct-9204	139	6	610	610	NUM
ct-9204	139	7	.	.	PUNCT
ct-9204	139	8	17	17	NUM
ct-9204	139	9	.	.	PUNCT
ct-9204	140	1	pocsfalvi	pocsfalvi	VERB
ct-9204	140	2	g	g	PROPN
ct-9204	140	3	,	,	PUNCT
ct-9204	140	4	stanly	stanly	PROPN
ct-9204	140	5	c	c	AUX
ct-9204	140	6	,	,	PUNCT
ct-9204	140	7	vilasi	vilasi	NOUN
ct-9204	140	8	a	a	X
ct-9204	140	9	,	,	PUNCT
ct-9204	140	10	et	et	PROPN
ct-9204	140	11	al	al	PROPN
ct-9204	140	12	:	:	PUNCT
ct-9204	140	13	mass	mass	ADJ
ct-9204	140	14	spectrometry	spectrometry	NOUN
ct-9204	140	15	of	of	ADP
ct-9204	140	16	extracellular	extracellular	ADJ
ct-9204	140	17	vesicles	vesicle	NOUN
ct-9204	140	18	.	.	PUNCT
ct-9204	141	1	mass	mass	PROPN
ct-9204	141	2	spectrom	spectrom	PROPN
ct-9204	141	3	rev	rev	VERB
ct-9204	141	4	2016;35:3	2016;35:3	NUM
ct-9204	141	5	-	-	SYM
ct-9204	141	6	21	21	NUM
ct-9204	141	7	.	.	PUNCT
ct-9204	141	8	18	18	NUM
ct-9204	141	9	.	.	PUNCT
ct-9204	142	1	pfrieger	pfrieger	NOUN
ct-9204	142	2	fw	fw	PROPN
ct-9204	142	3	,	,	PUNCT
ct-9204	142	4	vitale	vitale	PROPN
ct-9204	142	5	n	n	CCONJ
ct-9204	142	6	:	:	PUNCT
ct-9204	142	7	cholesterol	cholesterol	NOUN
ct-9204	142	8	and	and	CCONJ
ct-9204	142	9	the	the	DET
ct-9204	142	10	journey	journey	NOUN
ct-9204	142	11	of	of	ADP
ct-9204	142	12	extracellular	extracellular	ADJ
ct-9204	142	13	vesicles	vesicle	NOUN
ct-9204	142	14	.	.	PUNCT
ct-9204	143	1	j	j	PROPN
ct-9204	143	2	lipid	lipid	PROPN
ct-9204	143	3	res	re	VERB
ct-9204	143	4	2018;59:2255	2018;59:2255	NUM
ct-9204	143	5	-	-	SYM
ct-9204	143	6	2261	2261	NUM
ct-9204	143	7	.	.	PUNCT
ct-9204	144	1	19	19	NUM
ct-9204	144	2	.	.	NOUN
ct-9204	144	3	théry	théry	PROPN
ct-9204	144	4	c	c	NOUN
ct-9204	144	5	,	,	PUNCT
ct-9204	144	6	witwer	witwer	NOUN
ct-9204	144	7	kw	kw	PROPN
ct-9204	144	8	,	,	PUNCT
ct-9204	144	9	aikawa	aikawa	PROPN
ct-9204	144	10	e	e	PROPN
ct-9204	144	11	,	,	PUNCT
ct-9204	144	12	et	et	PROPN
ct-9204	144	13	al	al	PROPN
ct-9204	144	14	:	:	PUNCT
ct-9204	144	15	minimal	minimal	ADJ
ct-9204	144	16	information	information	NOUN
ct-9204	144	17	for	for	ADP
ct-9204	144	18	studies	study	NOUN
ct-9204	144	19	of	of	ADP
ct-9204	144	20	extracellular	extracellular	ADJ
ct-9204	144	21	vesicles	vesicle	NOUN
ct-9204	144	22	2018	2018	NUM
ct-9204	144	23	(	(	PUNCT
ct-9204	144	24	misev2018	misev2018	NOUN
ct-9204	144	25	):	):	PUNCT
ct-9204	144	26	a	a	DET
ct-9204	144	27	position	position	NOUN
ct-9204	144	28	statement	statement	NOUN
ct-9204	144	29	of	of	ADP
ct-9204	144	30	the	the	DET
ct-9204	144	31	international	international	ADJ
ct-9204	144	32	society	society	NOUN
ct-9204	144	33	for	for	ADP
ct-9204	144	34	extracellular	extracellular	ADJ
ct-9204	144	35	vesicles	vesicle	NOUN
ct-9204	144	36	and	and	CCONJ
ct-9204	144	37	update	update	NOUN
ct-9204	144	38	of	of	ADP
ct-9204	144	39	the	the	DET
ct-9204	144	40	misev2014	misev2014	PROPN
ct-9204	144	41	guidelines	guideline	NOUN
ct-9204	144	42	.	.	PUNCT
ct-9204	145	1	j	j	PROPN
ct-9204	145	2	extracell	extracell	PROPN
ct-9204	145	3	vesicles	vesicle	NOUN
ct-9204	145	4	2018;7:1535750	2018;7:1535750	NOUN
ct-9204	145	5	.	.	PUNCT
ct-9204	146	1	20	20	NUM
ct-9204	146	2	.	.	PUNCT
ct-9204	147	1	mulcahy	mulcahy	PROPN
ct-9204	147	2	la	la	PROPN
ct-9204	147	3	,	,	PUNCT
ct-9204	147	4	pink	pink	PROPN
ct-9204	147	5	rc	rc	PROPN
ct-9204	147	6	,	,	PUNCT
ct-9204	147	7	carter	carter	PROPN
ct-9204	147	8	drf	drf	PROPN
ct-9204	147	9	:	:	PUNCT
ct-9204	147	10	routes	route	NOUN
ct-9204	147	11	and	and	CCONJ
ct-9204	147	12	mechanisms	mechanism	NOUN
ct-9204	147	13	of	of	ADP
ct-9204	147	14	extracellular	extracellular	ADJ
ct-9204	147	15	vesicle	vesicle	NOUN
ct-9204	147	16	uptake	uptake	ADJ
ct-9204	147	17	.	.	PUNCT
ct-9204	148	1	j	j	PROPN
ct-9204	148	2	extracell	extracell	PROPN
ct-9204	148	3	vesicles	vesicle	VERB
ct-9204	148	4	2014;3:24641	2014;3:24641	NUM
ct-9204	148	5	.	.	PUNCT
ct-9204	149	1	21	21	NUM
ct-9204	149	2	.	.	PUNCT
ct-9204	150	1	lai	lai	PROPN
ct-9204	150	2	cp	cp	PROPN
ct-9204	150	3	,	,	PUNCT
ct-9204	150	4	kim	kim	PROPN
ct-9204	150	5	ey	ey	PROPN
ct-9204	150	6	,	,	PUNCT
ct-9204	150	7	badr	badr	PROPN
ct-9204	150	8	ce	ce	PROPN
ct-9204	150	9	,	,	PUNCT
ct-9204	150	10	et	et	PROPN
ct-9204	150	11	al	al	PROPN
ct-9204	150	12	:	:	PUNCT
ct-9204	150	13	visualization	visualization	NOUN
ct-9204	150	14	and	and	CCONJ
ct-9204	150	15	tracking	tracking	NOUN
ct-9204	150	16	of	of	ADP
ct-9204	150	17	tumour	tumour	ADJ
ct-9204	150	18	extracellular	extracellular	ADJ
ct-9204	150	19	vesicle	vesicle	NOUN
ct-9204	150	20	delivery	delivery	NOUN
ct-9204	150	21	and	and	CCONJ
ct-9204	150	22	rna	rna	NOUN
ct-9204	150	23	translation	translation	NOUN
ct-9204	150	24	using	use	VERB
ct-9204	150	25	multiplexed	multiplexed	ADJ
ct-9204	150	26	reporters	reporter	NOUN
ct-9204	150	27	.	.	PUNCT
ct-9204	151	1	nat	nat	PROPN
ct-9204	151	2	commun	commun	PROPN
ct-9204	151	3	2015;6:7029	2015;6:7029	PROPN
ct-9204	151	4	.	.	PUNCT
ct-9204	152	1	22	22	NUM
ct-9204	152	2	.	.	PUNCT
ct-9204	152	3	robbins	robbins	PROPN
ct-9204	152	4	pd	pd	PROPN
ct-9204	152	5	,	,	PUNCT
ct-9204	152	6	morelli	morelli	PROPN
ct-9204	152	7	ae	ae	PROPN
ct-9204	152	8	:	:	PUNCT
ct-9204	152	9	regulation	regulation	NOUN
ct-9204	152	10	of	of	ADP
ct-9204	152	11	immune	immune	ADJ
ct-9204	152	12	responses	response	NOUN
ct-9204	152	13	by	by	ADP
ct-9204	152	14	extracellular	extracellular	ADJ
ct-9204	152	15	vesicles	vesicle	NOUN
ct-9204	152	16	.	.	PUNCT
ct-9204	153	1	nat	nat	PROPN
ct-9204	153	2	rev	rev	VERB
ct-9204	153	3	immunol	immunol	NOUN
ct-9204	153	4	2014;14:195	2014;14:195	PROPN
ct-9204	153	5	-	-	SYM
ct-9204	153	6	208	208	NUM
ct-9204	153	7	.	.	PUNCT
ct-9204	154	1	23	23	NUM
ct-9204	154	2	.	.	PUNCT
ct-9204	155	1	lane	lane	NOUN
ct-9204	155	2	r	r	NOUN
ct-9204	155	3	,	,	PUNCT
ct-9204	155	4	korbie	korbie	NOUN
ct-9204	155	5	d	d	PROPN
ct-9204	155	6	,	,	PUNCT
ct-9204	155	7	hill	hill	PROPN
ct-9204	155	8	m	m	PROPN
ct-9204	155	9	,	,	PUNCT
ct-9204	155	10	et	et	PROPN
ct-9204	155	11	al	al	PROPN
ct-9204	155	12	:	:	PUNCT
ct-9204	155	13	extracellular	extracellular	ADJ
ct-9204	155	14	vesicles	vesicle	NOUN
ct-9204	155	15	as	as	ADP
ct-9204	155	16	circulating	circulate	VERB
ct-9204	155	17	cancer	cancer	NOUN
ct-9204	155	18	biomarkers	biomarker	NOUN
ct-9204	155	19	:	:	PUNCT
ct-9204	155	20	opportunities	opportunity	NOUN
ct-9204	155	21	and	and	CCONJ
ct-9204	155	22	challenges	challenge	NOUN
ct-9204	155	23	.	.	PUNCT
ct-9204	156	1	clin	clin	PROPN
ct-9204	156	2	transl	transl	PROPN
ct-9204	156	3	med	me	VERB
ct-9204	156	4	2018;7:14	2018;7:14	PROPN
ct-9204	156	5	-	-	PUNCT
ct-9204	156	6	25	25	NUM
ct-9204	156	7	.	.	PUNCT
ct-9204	157	1	24	24	NUM
ct-9204	157	2	.	.	PUNCT
ct-9204	158	1	usman	usman	PROPN
ct-9204	158	2	wm	wm	PROPN
ct-9204	158	3	,	,	PUNCT
ct-9204	158	4	pham	pham	PROPN
ct-9204	158	5	tc	tc	PROPN
ct-9204	158	6	,	,	PUNCT
ct-9204	158	7	kwok	kwok	PROPN
ct-9204	158	8	yy	yy	PROPN
ct-9204	158	9	,	,	PUNCT
ct-9204	158	10	et	et	PROPN
ct-9204	158	11	al	al	PROPN
ct-9204	158	12	:	:	PUNCT
ct-9204	158	13	efficient	efficient	ADJ
ct-9204	158	14	rna	rna	NOUN
ct-9204	158	15	drug	drug	NOUN
ct-9204	158	16	delivery	delivery	NOUN
ct-9204	158	17	using	use	VERB
ct-9204	158	18	red	red	ADJ
ct-9204	158	19	blood	blood	NOUN
ct-9204	158	20	cell	cell	NOUN
ct-9204	158	21	extracellular	extracellular	ADJ
ct-9204	158	22	vesicles	vesicle	NOUN
ct-9204	158	23	.	.	PUNCT
ct-9204	159	1	nat	nat	PROPN
ct-9204	159	2	commun	commun	PROPN
ct-9204	159	3	2018;9:2359	2018;9:2359	PROPN
ct-9204	159	4	.	.	PUNCT
ct-9204	160	1	25	25	NUM
ct-9204	160	2	.	.	PUNCT
ct-9204	161	1	yang	yang	PROPN
ct-9204	161	2	y	y	PROPN
ct-9204	161	3	,	,	PUNCT
ct-9204	161	4	hong	hong	PROPN
ct-9204	161	5	y	y	PROPN
ct-9204	161	6	,	,	PUNCT
ct-9204	161	7	cho	cho	PROPN
ct-9204	161	8	e	e	NOUN
ct-9204	161	9	,	,	PUNCT
ct-9204	161	10	et	et	PROPN
ct-9204	161	11	al	al	PROPN
ct-9204	161	12	:	:	PUNCT
ct-9204	161	13	extracellular	extracellular	ADJ
ct-9204	161	14	vesicles	vesicle	NOUN
ct-9204	161	15	as	as	ADP
ct-9204	161	16	a	a	DET
ct-9204	161	17	platform	platform	NOUN
ct-9204	161	18	for	for	ADP
ct-9204	161	19	membrane	membrane	NOUN
ct-9204	161	20	-	-	PUNCT
ct-9204	161	21	associated	associate	VERB
ct-9204	161	22	therapeutic	therapeutic	ADJ
ct-9204	161	23	protein	protein	NOUN
ct-9204	161	24	delivery	delivery	NOUN
ct-9204	161	25	.	.	PUNCT
ct-9204	162	1	j	j	PROPN
ct-9204	162	2	extracell	extracell	PROPN
ct-9204	162	3	vesicles	vesicle	VERB
ct-9204	162	4	2018;7:1440131	2018;7:1440131	NUM
ct-9204	162	5	.	.	PUNCT
ct-9204	163	1	26	26	NUM
ct-9204	163	2	.	.	PUNCT
ct-9204	164	1	machtinger	machting	ADJ
ct-9204	164	2	r	r	NOUN
ct-9204	164	3	,	,	PUNCT
ct-9204	164	4	laurent	laurent	PROPN
ct-9204	164	5	lc	lc	PROPN
ct-9204	164	6	,	,	PUNCT
ct-9204	164	7	baccarelli	baccarelli	VERB
ct-9204	164	8	aa	aa	NOUN
ct-9204	164	9	:	:	PUNCT
ct-9204	164	10	extracellular	extracellular	ADJ
ct-9204	164	11	vesicles	vesicle	NOUN
ct-9204	164	12	:	:	PUNCT
ct-9204	164	13	roles	role	NOUN
ct-9204	164	14	in	in	ADP
ct-9204	164	15	gamete	gamete	ADJ
ct-9204	164	16	maturation	maturation	NOUN
ct-9204	164	17	,	,	PUNCT
ct-9204	164	18	fertilization	fertilization	NOUN
ct-9204	164	19	and	and	CCONJ
ct-9204	164	20	embryo	embryo	NOUN
ct-9204	164	21	implantation	implantation	NOUN
ct-9204	164	22	.	.	PUNCT
ct-9204	165	1	hum	hum	PROPN
ct-9204	165	2	reprod	reprod	AUX
ct-9204	165	3	update	update	VERB
ct-9204	165	4	2016;22:182	2016;22:182	PROPN
ct-9204	165	5	-	-	PUNCT
ct-9204	165	6	193	193	NUM
ct-9204	165	7	.	.	PUNCT
ct-9204	166	1	clinical	clinical	ADJ
ct-9204	166	2	theriogenology	theriogenology	NOUN
ct-9204	166	3	•	•	NOUN
ct-9204	166	4	volume	volume	NOUN
ct-9204	166	5	12	12	NUM
ct-9204	166	6	number	number	NOUN
ct-9204	166	7	2	2	NUM
ct-9204	166	8	•	•	NOUN
ct-9204	166	9	june	june	PROPN
ct-9204	166	10	2020	2020	NUM
ct-9204	166	11	97	97	NUM
ct-9204	166	12	27	27	NUM
ct-9204	166	13	.	.	PUNCT
ct-9204	167	1	almiñana	almiñana	PROPN
ct-9204	167	2	c	c	PROPN
ct-9204	167	3	,	,	PUNCT
ct-9204	167	4	bauersachs	bauersachs	PROPN
ct-9204	167	5	s	s	PART
ct-9204	167	6	:	:	PUNCT
ct-9204	167	7	extracellular	extracellular	ADJ
ct-9204	167	8	vesicles	vesicle	NOUN
ct-9204	167	9	in	in	ADP
ct-9204	167	10	the	the	DET
ct-9204	167	11	oviduct	oviduct	NOUN
ct-9204	167	12	:	:	PUNCT
ct-9204	167	13	progress	progress	NOUN
ct-9204	167	14	,	,	PUNCT
ct-9204	167	15	challenges	challenge	NOUN
ct-9204	167	16	and	and	CCONJ
ct-9204	167	17	implications	implication	NOUN
ct-9204	167	18	for	for	ADP
ct-9204	167	19	the	the	DET
ct-9204	167	20	reproductive	reproductive	ADJ
ct-9204	167	21	success	success	NOUN
ct-9204	167	22	.	.	PUNCT
ct-9204	168	1	bioengineering	bioengineere	VERB
ct-9204	168	2	2019;6:32	2019;6:32	NOUN
ct-9204	168	3	-	-	PUNCT
ct-9204	168	4	57	57	NUM
ct-9204	168	5	.	.	PUNCT
ct-9204	169	1	28	28	NUM
ct-9204	169	2	.	.	PUNCT
ct-9204	170	1	andrade	andrade	PROPN
ct-9204	170	2	gm	gm	PROPN
ct-9204	170	3	,	,	PUNCT
ct-9204	170	4	bridi	bridi	NOUN
ct-9204	170	5	a	a	PRON
ct-9204	170	6	,	,	PUNCT
ct-9204	170	7	gimenes	gimene	NOUN
ct-9204	170	8	lu	lu	PROPN
ct-9204	170	9	,	,	PUNCT
ct-9204	170	10	et	et	PROPN
ct-9204	170	11	al	al	PROPN
ct-9204	170	12	:	:	PUNCT
ct-9204	170	13	extracellular	extracellular	ADJ
ct-9204	170	14	vesicles	vesicle	NOUN
ct-9204	170	15	and	and	CCONJ
ct-9204	170	16	its	its	PRON
ct-9204	170	17	advances	advance	NOUN
ct-9204	170	18	in	in	ADP
ct-9204	170	19	female	female	ADJ
ct-9204	170	20	reproduction	reproduction	NOUN
ct-9204	170	21	.	.	PUNCT
ct-9204	171	1	anim	anim	NOUN
ct-9204	171	2	reprod	reprod	PROPN
ct-9204	171	3	2019;16:31	2019;16:31	PROPN
ct-9204	171	4	-	-	SYM
ct-9204	171	5	38	38	NUM
ct-9204	171	6	.	.	PUNCT
ct-9204	171	7	29	29	NUM
ct-9204	171	8	.	.	PUNCT
ct-9204	172	1	barkalina	barkalina	PROPN
ct-9204	172	2	n	n	PROPN
ct-9204	172	3	,	,	PUNCT
ct-9204	172	4	jones	jones	PROPN
ct-9204	172	5	c	c	PROPN
ct-9204	172	6	,	,	PUNCT
ct-9204	172	7	wood	wood	NOUN
ct-9204	172	8	mja	mja	NOUN
ct-9204	172	9	,	,	PUNCT
ct-9204	172	10	et	et	PROPN
ct-9204	172	11	al	al	PROPN
ct-9204	172	12	:	:	PUNCT
ct-9204	172	13	extracellular	extracellular	ADJ
ct-9204	172	14	vesicle	vesicle	NOUN
ct-9204	172	15	-	-	PUNCT
ct-9204	172	16	mediated	mediate	VERB
ct-9204	172	17	delivery	delivery	NOUN
ct-9204	172	18	of	of	ADP
ct-9204	172	19	molecular	molecular	ADJ
ct-9204	172	20	compounds	compound	NOUN
ct-9204	172	21	into	into	ADP
ct-9204	172	22	gametes	gamete	NOUN
ct-9204	172	23	and	and	CCONJ
ct-9204	172	24	embryos	embryo	NOUN
ct-9204	172	25	:	:	PUNCT
ct-9204	172	26	learning	learn	VERB
ct-9204	172	27	from	from	ADP
ct-9204	172	28	nature	nature	NOUN
ct-9204	172	29	.	.	PUNCT
ct-9204	173	1	hum	hum	PROPN
ct-9204	173	2	reprod	reprod	PROPN
ct-9204	173	3	update	update	VERB
ct-9204	173	4	2015;21:627	2015;21:627	NUM
ct-9204	173	5	-	-	SYM
ct-9204	173	6	639	639	NUM
ct-9204	173	7	.	.	PUNCT
ct-9204	174	1	30	30	NUM
ct-9204	174	2	.	.	X
ct-9204	174	3	de	de	PROPN
ct-9204	174	4	ávila	ávila	PROPN
ct-9204	174	5	acfcm	acfcm	PROPN
ct-9204	174	6	,	,	PUNCT
ct-9204	174	7	da	da	PROPN
ct-9204	174	8	silveira	silveira	PROPN
ct-9204	174	9	jc	jc	PROPN
ct-9204	174	10	:	:	PUNCT
ct-9204	174	11	role	role	NOUN
ct-9204	174	12	of	of	ADP
ct-9204	174	13	extracellular	extracellular	ADJ
ct-9204	174	14	vesicles	vesicle	NOUN
ct-9204	174	15	during	during	ADP
ct-9204	174	16	oocyte	oocyte	ADJ
ct-9204	174	17	maturation	maturation	NOUN
ct-9204	174	18	and	and	CCONJ
ct-9204	174	19	early	early	ADJ
ct-9204	174	20	embryo	embryo	NOUN
ct-9204	174	21	development	development	NOUN
ct-9204	174	22	.	.	PUNCT
ct-9204	175	1	reprod	reprod	PROPN
ct-9204	175	2	fertil	fertil	AUX
ct-9204	175	3	dev	dev	PROPN
ct-9204	175	4	2020;32:56	2020;32:56	PROPN
ct-9204	175	5	-	-	SYM
ct-9204	175	6	64	64	NUM
ct-9204	175	7	.	.	PUNCT
ct-9204	176	1	31	31	NUM
ct-9204	176	2	.	.	PUNCT
ct-9204	177	1	hermo	hermo	PROPN
ct-9204	177	2	l	l	PROPN
ct-9204	177	3	,	,	PUNCT
ct-9204	177	4	jacks	jack	NOUN
ct-9204	177	5	d	d	NOUN
ct-9204	177	6	:	:	PUNCT
ct-9204	177	7	nature	nature	NOUN
ct-9204	177	8	’s	’s	PART
ct-9204	177	9	ingenuity	ingenuity	NOUN
ct-9204	177	10	:	:	PUNCT
ct-9204	177	11	bypassing	bypass	VERB
ct-9204	177	12	the	the	DET
ct-9204	177	13	classical	classical	ADJ
ct-9204	177	14	secretory	secretory	ADJ
ct-9204	177	15	route	route	NOUN
ct-9204	177	16	via	via	ADP
ct-9204	177	17	apocrine	apocrine	ADJ
ct-9204	177	18	secretion	secretion	NOUN
ct-9204	177	19	.	.	PUNCT
ct-9204	178	1	mol	mol	PROPN
ct-9204	178	2	reprod	reprod	PROPN
ct-9204	178	3	dev	dev	PROPN
ct-9204	178	4	2002;63:394	2002;63:394	X
ct-9204	178	5	-	-	NUM
ct-9204	178	6	410	410	NUM
ct-9204	178	7	.	.	PUNCT
ct-9204	179	1	32	32	NUM
ct-9204	179	2	.	.	PUNCT
ct-9204	180	1	reilly	reilly	PROPN
ct-9204	180	2	jn	jn	PROPN
ct-9204	180	3	,	,	PUNCT
ct-9204	180	4	mclaughlin	mclaughlin	PROPN
ct-9204	180	5	ea	ea	PROPN
ct-9204	180	6	,	,	PUNCT
ct-9204	180	7	stanger	stanger	PROPN
ct-9204	180	8	sj	sj	PROPN
ct-9204	180	9	,	,	PUNCT
ct-9204	180	10	et	et	PROPN
ct-9204	180	11	al	al	PROPN
ct-9204	180	12	:	:	PUNCT
ct-9204	180	13	characterisation	characterisation	NOUN
ct-9204	180	14	of	of	ADP
ct-9204	180	15	mouse	mouse	NOUN
ct-9204	180	16	epididymosomes	epididymosome	NOUN
ct-9204	180	17	reveals	reveal	VERB
ct-9204	180	18	a	a	DET
ct-9204	180	19	complex	complex	ADJ
ct-9204	180	20	profile	profile	NOUN
ct-9204	180	21	of	of	ADP
ct-9204	180	22	micrornas	microrna	NOUN
ct-9204	180	23	and	and	CCONJ
ct-9204	180	24	a	a	DET
ct-9204	180	25	potential	potential	ADJ
ct-9204	180	26	mechanism	mechanism	NOUN
ct-9204	180	27	for	for	ADP
ct-9204	180	28	modification	modification	NOUN
ct-9204	180	29	of	of	ADP
ct-9204	180	30	the	the	DET
ct-9204	180	31	sperm	sperm	NOUN
ct-9204	180	32	epigenome	epigenome	NOUN
ct-9204	180	33	.	.	PUNCT
ct-9204	181	1	sci	sci	PROPN
ct-9204	181	2	rep	rep	PROPN
ct-9204	181	3	2016;6:1	2016;6:1	NUM
ct-9204	181	4	-	-	SYM
ct-9204	181	5	15	15	NUM
ct-9204	181	6	.	.	PUNCT
ct-9204	181	7	33	33	NUM
ct-9204	181	8	.	.	PUNCT
ct-9204	182	1	trigg	trigg	PROPN
ct-9204	182	2	na	na	PROPN
ct-9204	182	3	,	,	PUNCT
ct-9204	182	4	eamens	eamens	PROPN
ct-9204	182	5	al	al	PROPN
ct-9204	182	6	,	,	PUNCT
ct-9204	182	7	nixon	nixon	PROPN
ct-9204	182	8	b	b	PROPN
ct-9204	182	9	:	:	PUNCT
ct-9204	182	10	the	the	DET
ct-9204	182	11	contribution	contribution	NOUN
ct-9204	182	12	of	of	ADP
ct-9204	182	13	epididymosomes	epididymosome	NOUN
ct-9204	182	14	to	to	ADP
ct-9204	182	15	the	the	DET
ct-9204	182	16	sperm	sperm	NOUN
ct-9204	182	17	small	small	ADJ
ct-9204	182	18	rna	rna	NOUN
ct-9204	182	19	profile	profile	NOUN
ct-9204	182	20	.	.	PUNCT
ct-9204	183	1	reproduction	reproduction	NOUN
ct-9204	183	2	2019;157	2019;157	NUM
ct-9204	183	3	:	:	PUNCT
ct-9204	183	4	r209	r209	PROPN
ct-9204	183	5	-	-	PUNCT
ct-9204	183	6	r223	r223	PROPN
ct-9204	183	7	.	.	PUNCT
ct-9204	184	1	34	34	NUM
ct-9204	184	2	.	.	PUNCT
ct-9204	185	1	sullivan	sullivan	PROPN
ct-9204	185	2	r	r	PROPN
ct-9204	185	3	,	,	PUNCT
ct-9204	185	4	frenette	frenette	NOUN
ct-9204	185	5	g	g	NOUN
ct-9204	185	6	,	,	PUNCT
ct-9204	185	7	girouard	girouard	NOUN
ct-9204	185	8	j	j	PROPN
ct-9204	185	9	:	:	PUNCT
ct-9204	185	10	epididymosomes	epididymosome	NOUN
ct-9204	185	11	are	be	AUX
ct-9204	185	12	involved	involve	VERB
ct-9204	185	13	in	in	ADP
ct-9204	185	14	the	the	DET
ct-9204	185	15	acquisition	acquisition	NOUN
ct-9204	185	16	of	of	ADP
ct-9204	185	17	new	new	ADJ
ct-9204	185	18	sperm	sperm	NOUN
ct-9204	185	19	proteins	protein	NOUN
ct-9204	185	20	during	during	ADP
ct-9204	185	21	epididymal	epididymal	ADJ
ct-9204	185	22	transit	transit	NOUN
ct-9204	185	23	.	.	PUNCT
ct-9204	186	1	asian	asian	PROPN
ct-9204	186	2	j	j	PROPN
ct-9204	186	3	androl	androl	PROPN
ct-9204	186	4	2007;9:483	2007;9:483	PROPN
ct-9204	186	5	-	-	PUNCT
ct-9204	186	6	491	491	NUM
ct-9204	186	7	.	.	PUNCT
ct-9204	186	8	35	35	NUM
ct-9204	186	9	.	.	PUNCT
ct-9204	187	1	nixon	nixon	PROPN
ct-9204	187	2	b	b	PROPN
ct-9204	187	3	,	,	PUNCT
ct-9204	187	4	de	de	X
ct-9204	187	5	iuliis	iuliis	PROPN
ct-9204	187	6	gn	gn	PROPN
ct-9204	187	7	,	,	PUNCT
ct-9204	187	8	hart	hart	PROPN
ct-9204	187	9	hm	hm	INTJ
ct-9204	187	10	,	,	PUNCT
ct-9204	187	11	et	et	PROPN
ct-9204	187	12	al	al	PROPN
ct-9204	187	13	:	:	PUNCT
ct-9204	187	14	proteomic	proteomic	ADJ
ct-9204	187	15	profiling	profiling	NOUN
ct-9204	187	16	of	of	ADP
ct-9204	187	17	mouse	mouse	NOUN
ct-9204	187	18	epididymosomes	epididymosome	NOUN
ct-9204	187	19	reveals	reveal	VERB
ct-9204	187	20	their	their	PRON
ct-9204	187	21	contributions	contribution	NOUN
ct-9204	187	22	to	to	ADP
ct-9204	187	23	post	post	ADJ
ct-9204	187	24	-	-	ADJ
ct-9204	187	25	testicular	testicular	ADJ
ct-9204	187	26	sperm	sperm	NOUN
ct-9204	187	27	maturation	maturation	NOUN
ct-9204	187	28	.	.	PUNCT
ct-9204	188	1	mol	mol	ADP
ct-9204	188	2	cell	cell	NOUN
ct-9204	188	3	proteomics	proteomic	NOUN
ct-9204	188	4	2019;18	2019;18	NUM
ct-9204	188	5	:	:	PUNCT
ct-9204	188	6	s91	s91	PROPN
ct-9204	188	7	-	-	PUNCT
ct-9204	188	8	s108	s108	PROPN
ct-9204	188	9	.	.	PUNCT
ct-9204	189	1	36	36	NUM
ct-9204	189	2	.	.	PUNCT
ct-9204	190	1	schwarz	schwarz	PROPN
ct-9204	190	2	a	a	PROPN
ct-9204	190	3	,	,	PUNCT
ct-9204	190	4	wennemuth	wennemuth	NOUN
ct-9204	190	5	g	g	NOUN
ct-9204	190	6	,	,	PUNCT
ct-9204	190	7	post	post	NOUN
ct-9204	190	8	h	h	NOUN
ct-9204	190	9	,	,	PUNCT
ct-9204	190	10	et	et	PROPN
ct-9204	190	11	al	al	PROPN
ct-9204	190	12	:	:	PUNCT
ct-9204	190	13	vesicular	vesicular	ADJ
ct-9204	190	14	transfer	transfer	NOUN
ct-9204	190	15	of	of	ADP
ct-9204	190	16	membrane	membrane	NOUN
ct-9204	190	17	components	component	NOUN
ct-9204	190	18	to	to	PART
ct-9204	190	19	bovine	bovine	VERB
ct-9204	190	20	epididymal	epididymal	ADJ
ct-9204	190	21	spermatozoa	spermatozoon	NOUN
ct-9204	190	22	.	.	PUNCT
ct-9204	191	1	cell	cell	NOUN
ct-9204	191	2	tissue	tissue	NOUN
ct-9204	191	3	res	re	NOUN
ct-9204	191	4	2013;353:549	2013;353:549	NUM
ct-9204	191	5	-	-	SYM
ct-9204	191	6	561	561	NUM
ct-9204	191	7	.	.	PUNCT
ct-9204	192	1	37	37	NUM
ct-9204	192	2	.	.	PUNCT
ct-9204	193	1	sullivan	sullivan	PROPN
ct-9204	193	2	r	r	NOUN
ct-9204	193	3	:	:	PUNCT
ct-9204	193	4	epididymosomes	epididymosome	NOUN
ct-9204	193	5	:	:	PUNCT
ct-9204	193	6	role	role	NOUN
ct-9204	193	7	of	of	ADP
ct-9204	193	8	extracellular	extracellular	ADJ
ct-9204	193	9	microvesicles	microvesicle	NOUN
ct-9204	193	10	in	in	ADP
ct-9204	193	11	sperm	sperm	NOUN
ct-9204	193	12	maturation	maturation	NOUN
ct-9204	193	13	.	.	PUNCT
ct-9204	194	1	front	front	ADJ
ct-9204	194	2	biosci	biosci	PROPN
ct-9204	194	3	(	(	PUNCT
ct-9204	194	4	schol	schol	PROPN
ct-9204	194	5	ed	ed	NOUN
ct-9204	194	6	)	)	PUNCT
ct-9204	194	7	2016;8:106	2016;8:106	NUM
ct-9204	194	8	-	-	SYM
ct-9204	194	9	114	114	NUM
ct-9204	194	10	.	.	PUNCT
ct-9204	195	1	38	38	NUM
ct-9204	195	2	.	.	PUNCT
ct-9204	196	1	girouard	girouard	PROPN
ct-9204	196	2	j	j	PROPN
ct-9204	196	3	,	,	PUNCT
ct-9204	196	4	frenette	frenette	NOUN
ct-9204	196	5	g	g	NOUN
ct-9204	196	6	,	,	PUNCT
ct-9204	196	7	sullivan	sullivan	PROPN
ct-9204	196	8	r	r	NOUN
ct-9204	196	9	:	:	PUNCT
ct-9204	196	10	comparative	comparative	ADJ
ct-9204	196	11	proteome	proteome	NOUN
ct-9204	196	12	and	and	CCONJ
ct-9204	196	13	lipid	lipid	NOUN
ct-9204	196	14	profiles	profile	NOUN
ct-9204	196	15	of	of	ADP
ct-9204	196	16	bovine	bovine	NOUN
ct-9204	196	17	epididymosomes	epididymosome	NOUN
ct-9204	196	18	collected	collect	VERB
ct-9204	196	19	in	in	ADP
ct-9204	196	20	the	the	DET
ct-9204	196	21	intraluminal	intraluminal	ADJ
ct-9204	196	22	compartment	compartment	NOUN
ct-9204	196	23	of	of	ADP
ct-9204	196	24	the	the	DET
ct-9204	196	25	caput	caput	NOUN
ct-9204	196	26	and	and	CCONJ
ct-9204	196	27	cauda	cauda	NOUN
ct-9204	196	28	epididymidis	epididymidi	NOUN
ct-9204	196	29	.	.	PUNCT
ct-9204	197	1	int	int	PROPN
ct-9204	198	1	j	j	PROPN
ct-9204	198	2	androl	androl	PROPN
ct-9204	198	3	2011;34	2011;34	PROPN
ct-9204	198	4	:	:	PUNCT
ct-9204	198	5	e475	e475	PROPN
ct-9204	198	6	-	-	PUNCT
ct-9204	198	7	e486	e486	PROPN
ct-9204	198	8	.	.	PROPN
ct-9204	198	9	39	39	NUM
ct-9204	198	10	.	.	PUNCT
ct-9204	199	1	cai	cai	PROPN
ct-9204	199	2	y	y	PROPN
ct-9204	199	3	,	,	PUNCT
ct-9204	199	4	yu	yu	PROPN
ct-9204	199	5	x	x	PROPN
ct-9204	199	6	,	,	PUNCT
ct-9204	199	7	hu	hu	PROPN
ct-9204	199	8	s	s	PART
ct-9204	199	9	,	,	PUNCT
ct-9204	199	10	et	et	PROPN
ct-9204	199	11	al	al	PROPN
ct-9204	199	12	:	:	PUNCT
ct-9204	199	13	a	a	DET
ct-9204	199	14	brief	brief	ADJ
ct-9204	199	15	review	review	NOUN
ct-9204	199	16	on	on	ADP
ct-9204	199	17	the	the	DET
ct-9204	199	18	mechanisms	mechanism	NOUN
ct-9204	199	19	of	of	ADP
ct-9204	199	20	mirna	mirna	PROPN
ct-9204	199	21	regulation	regulation	PROPN
ct-9204	199	22	.	.	PUNCT
ct-9204	200	1	genom	genom	PROPN
ct-9204	200	2	proteom	proteom	PROPN
ct-9204	200	3	bioinf	bioinf	PROPN
ct-9204	200	4	2009;7	2009;7	NOUN
ct-9204	200	5	:	:	PUNCT
ct-9204	200	6	147	147	NUM
ct-9204	200	7	-	-	SYM
ct-9204	200	8	154	154	NUM
ct-9204	200	9	.	.	PUNCT
ct-9204	201	1	40	40	NUM
ct-9204	201	2	.	.	PUNCT
ct-9204	202	1	rompala	rompala	PROPN
ct-9204	202	2	gr	gr	PROPN
ct-9204	202	3	,	,	PUNCT
ct-9204	202	4	mounier	mounier	NOUN
ct-9204	202	5	a	a	NOUN
ct-9204	202	6	,	,	PUNCT
ct-9204	202	7	wolfe	wolfe	PROPN
ct-9204	202	8	cm	cm	PROPN
ct-9204	202	9	,	,	PUNCT
ct-9204	202	10	et	et	PROPN
ct-9204	202	11	al	al	PROPN
ct-9204	202	12	:	:	PUNCT
ct-9204	202	13	heavy	heavy	ADJ
ct-9204	202	14	chronic	chronic	ADJ
ct-9204	202	15	intermittent	intermittent	ADJ
ct-9204	202	16	ethanol	ethanol	NOUN
ct-9204	202	17	exposure	exposure	NOUN
ct-9204	202	18	alters	alter	VERB
ct-9204	202	19	small	small	ADJ
ct-9204	202	20	noncoding	noncoding	ADJ
ct-9204	202	21	rnas	rna	NOUN
ct-9204	202	22	in	in	ADP
ct-9204	202	23	mouse	mouse	NOUN
ct-9204	202	24	sperm	sperm	NOUN
ct-9204	202	25	and	and	CCONJ
ct-9204	202	26	epididymosomes	epididymosome	NOUN
ct-9204	202	27	.	.	PUNCT
ct-9204	203	1	front	front	ADJ
ct-9204	203	2	genet	genet	PROPN
ct-9204	203	3	2018;9:32	2018;9:32	NOUN
ct-9204	203	4	.	.	PUNCT
ct-9204	204	1	41	41	NUM
ct-9204	204	2	.	.	PUNCT
ct-9204	205	1	rowlison	rowlison	PROPN
ct-9204	205	2	t	t	PROPN
ct-9204	205	3	,	,	PUNCT
ct-9204	205	4	ottinger	ottinger	PROPN
ct-9204	205	5	ma	ma	PROPN
ct-9204	205	6	,	,	PUNCT
ct-9204	205	7	comizzoli	comizzoli	VERB
ct-9204	205	8	p	p	NOUN
ct-9204	205	9	:	:	PUNCT
ct-9204	205	10	key	key	ADJ
ct-9204	205	11	factors	factor	NOUN
ct-9204	205	12	enhancing	enhance	VERB
ct-9204	205	13	sperm	sperm	NOUN
ct-9204	205	14	fertilizing	fertilize	VERB
ct-9204	205	15	ability	ability	NOUN
ct-9204	205	16	are	be	AUX
ct-9204	205	17	transferred	transfer	VERB
ct-9204	205	18	from	from	ADP
ct-9204	205	19	the	the	DET
ct-9204	205	20	epididymis	epididymis	NOUN
ct-9204	205	21	to	to	ADP
ct-9204	205	22	the	the	DET
ct-9204	205	23	spermatozoa	spermatozoa	NOUN
ct-9204	205	24	via	via	ADP
ct-9204	205	25	epididymosomes	epididymosome	NOUN
ct-9204	205	26	in	in	ADP
ct-9204	205	27	the	the	DET
ct-9204	205	28	domestic	domestic	ADJ
ct-9204	205	29	cat	cat	NOUN
ct-9204	205	30	model	model	NOUN
ct-9204	205	31	.	.	PUNCT
ct-9204	206	1	j	j	PROPN
ct-9204	206	2	assist	assist	VERB
ct-9204	206	3	reprod	reprod	PROPN
ct-9204	206	4	genet	genet	PROPN
ct-9204	206	5	2018	2018	NUM
ct-9204	206	6	;	;	PUNCT
ct-9204	206	7	35:221	35:221	NUM
ct-9204	206	8	-	-	SYM
ct-9204	206	9	228	228	NUM
ct-9204	206	10	.	.	PUNCT
ct-9204	207	1	42	42	NUM
ct-9204	207	2	.	.	PUNCT
ct-9204	208	1	conine	conine	PROPN
ct-9204	208	2	c	c	NOUN
ct-9204	208	3	,	,	PUNCT
ct-9204	208	4	sun	sun	PROPN
ct-9204	208	5	f	f	PROPN
ct-9204	208	6	,	,	PUNCT
ct-9204	208	7	song	song	PROPN
ct-9204	208	8	l	l	PROPN
ct-9204	208	9	,	,	PUNCT
ct-9204	208	10	et	et	PROPN
ct-9204	208	11	al	al	PROPN
ct-9204	208	12	:	:	PUNCT
ct-9204	208	13	small	small	ADJ
ct-9204	208	14	rnas	rna	NOUN
ct-9204	208	15	gained	gain	VERB
ct-9204	208	16	during	during	ADP
ct-9204	208	17	epididymal	epididymal	ADJ
ct-9204	208	18	transit	transit	NOUN
ct-9204	208	19	of	of	ADP
ct-9204	208	20	sperm	sperm	NOUN
ct-9204	208	21	are	be	AUX
ct-9204	208	22	essential	essential	ADJ
ct-9204	208	23	for	for	ADP
ct-9204	208	24	embryonic	embryonic	ADJ
ct-9204	208	25	development	development	NOUN
ct-9204	208	26	in	in	ADP
ct-9204	208	27	mice	mouse	NOUN
ct-9204	208	28	.	.	PUNCT
ct-9204	209	1	dev	dev	PROPN
ct-9204	209	2	cell	cell	NOUN
ct-9204	209	3	2018;46:470	2018;46:470	NOUN
ct-9204	209	4	-	-	SYM
ct-9204	209	5	480.e473	480.e473	NUM
ct-9204	209	6	.	.	PUNCT
ct-9204	210	1	43	43	NUM
ct-9204	210	2	.	.	PUNCT
ct-9204	211	1	aalberts	aalbert	NOUN
ct-9204	211	2	m	m	PROPN
ct-9204	211	3	,	,	PUNCT
ct-9204	211	4	stout	stout	PROPN
ct-9204	211	5	ta	ta	ADP
ct-9204	211	6	,	,	PUNCT
ct-9204	211	7	stoorvogel	stoorvogel	ADV
ct-9204	211	8	w	w	PROPN
ct-9204	211	9	:	:	PUNCT
ct-9204	211	10	prostasomes	prostasome	NOUN
ct-9204	211	11	:	:	PUNCT
ct-9204	211	12	extracellular	extracellular	ADJ
ct-9204	211	13	vesicles	vesicle	NOUN
ct-9204	211	14	from	from	ADP
ct-9204	211	15	the	the	DET
ct-9204	211	16	prostate	prostate	NOUN
ct-9204	211	17	.	.	PUNCT
ct-9204	212	1	reproduction	reproduction	NOUN
ct-9204	212	2	2014;147	2014;147	NUM
ct-9204	212	3	:	:	PUNCT
ct-9204	212	4	r1	r1	NOUN
ct-9204	212	5	-	-	PUNCT
ct-9204	212	6	r14	r14	NOUN
ct-9204	212	7	.	.	PUNCT
ct-9204	213	1	44	44	NUM
ct-9204	213	2	.	.	PUNCT
ct-9204	214	1	utleg	utleg	PROPN
ct-9204	214	2	ag	ag	PROPN
ct-9204	214	3	,	,	PUNCT
ct-9204	214	4	yi	yi	PROPN
ct-9204	214	5	ec	ec	PROPN
ct-9204	214	6	,	,	PUNCT
ct-9204	214	7	xie	xie	PROPN
ct-9204	214	8	t	t	PROPN
ct-9204	214	9	,	,	PUNCT
ct-9204	214	10	et	et	PROPN
ct-9204	214	11	al	al	PROPN
ct-9204	214	12	:	:	PUNCT
ct-9204	214	13	proteomic	proteomic	ADJ
ct-9204	214	14	analysis	analysis	NOUN
ct-9204	214	15	of	of	ADP
ct-9204	214	16	human	human	ADJ
ct-9204	214	17	prostasomes	prostasome	NOUN
ct-9204	214	18	.	.	PUNCT
ct-9204	215	1	prostate	prostate	NOUN
ct-9204	215	2	2003;56:150	2003;56:150	NUM
ct-9204	215	3	-	-	SYM
ct-9204	215	4	161	161	NUM
ct-9204	215	5	.	.	PUNCT
ct-9204	216	1	45	45	NUM
ct-9204	216	2	.	.	PUNCT
ct-9204	216	3	park	park	PROPN
ct-9204	217	1	k	k	PROPN
ct-9204	217	2	-	-	PROPN
ct-9204	217	3	h	h	PROPN
ct-9204	217	4	,	,	PUNCT
ct-9204	217	5	kim	kim	PROPN
ct-9204	217	6	b	b	PROPN
ct-9204	217	7	-	-	PUNCT
ct-9204	217	8	j	j	PROPN
ct-9204	217	9	,	,	PUNCT
ct-9204	217	10	kang	kang	PROPN
ct-9204	217	11	j	j	PROPN
ct-9204	217	12	,	,	PUNCT
ct-9204	217	13	et	et	PROPN
ct-9204	217	14	al	al	PROPN
ct-9204	217	15	:	:	PUNCT
ct-9204	217	16	ca2	ca2	PROPN
ct-9204	217	17	+	+	NOUN
ct-9204	217	18	signaling	signal	VERB
ct-9204	217	19	tools	tool	NOUN
ct-9204	217	20	acquired	acquire	VERB
ct-9204	217	21	from	from	ADP
ct-9204	217	22	prostasomes	prostasome	NOUN
ct-9204	217	23	are	be	AUX
ct-9204	217	24	required	require	VERB
ct-9204	217	25	for	for	ADP
ct-9204	217	26	progesteroneinduced	progesteroneinduce	VERB
ct-9204	217	27	sperm	sperm	NOUN
ct-9204	217	28	motility	motility	NOUN
ct-9204	217	29	.	.	PUNCT
ct-9204	218	1	sci	sci	PROPN
ct-9204	218	2	singal	singal	PROPN
ct-9204	218	3	2011;4	2011;4	PROPN
ct-9204	219	1	ra31	ra31	PROPN
ct-9204	219	2	.	.	PUNCT
ct-9204	219	3	doi	doi	NOUN
ct-9204	219	4	:	:	PUNCT
ct-9204	219	5	10.1126	10.1126	NUM
ct-9204	219	6	/	/	SYM
ct-9204	219	7	scisignal.2001595	scisignal.2001595	NOUN
ct-9204	219	8	.	.	PUNCT
ct-9204	220	1	46	46	NUM
ct-9204	220	2	.	.	PUNCT
ct-9204	221	1	ronquist	ronquist	PROPN
ct-9204	221	2	kg	kg	PROPN
ct-9204	221	3	,	,	PUNCT
ct-9204	221	4	ek	ek	PROPN
ct-9204	221	5	b	b	PROPN
ct-9204	221	6	,	,	PUNCT
ct-9204	221	7	morrell	morrell	PROPN
ct-9204	221	8	j	j	PROPN
ct-9204	221	9	,	,	PUNCT
ct-9204	221	10	et	et	PROPN
ct-9204	221	11	al	al	PROPN
ct-9204	221	12	:	:	PUNCT
ct-9204	221	13	prostasomes	prostasome	NOUN
ct-9204	221	14	from	from	ADP
ct-9204	221	15	four	four	NUM
ct-9204	221	16	different	different	ADJ
ct-9204	221	17	species	specie	NOUN
ct-9204	221	18	are	be	AUX
ct-9204	221	19	able	able	ADJ
ct-9204	221	20	to	to	PART
ct-9204	221	21	produce	produce	VERB
ct-9204	221	22	extracellular	extracellular	ADJ
ct-9204	221	23	adenosine	adenosine	NOUN
ct-9204	221	24	triphosphate	triphosphate	NOUN
ct-9204	221	25	(	(	PUNCT
ct-9204	221	26	atp	atp	PROPN
ct-9204	221	27	)	)	PUNCT
ct-9204	221	28	.	.	PUNCT
ct-9204	222	1	bba	bba	PROPN
ct-9204	222	2	gen	gen	PROPN
ct-9204	222	3	subjects	subject	NOUN
ct-9204	222	4	2013;1830:4604	2013;1830:4604	NUM
ct-9204	222	5	-	-	SYM
ct-9204	222	6	4610	4610	NUM
ct-9204	222	7	.	.	PUNCT
ct-9204	223	1	47	47	NUM
ct-9204	223	2	.	.	PUNCT
ct-9204	224	1	brouwers	brouwer	NOUN
ct-9204	224	2	jf	jf	PROPN
ct-9204	224	3	,	,	PUNCT
ct-9204	224	4	aalberts	aalbert	VERB
ct-9204	224	5	m	m	PROPN
ct-9204	224	6	,	,	PUNCT
ct-9204	224	7	jansen	jansen	PROPN
ct-9204	224	8	jw	jw	PROPN
ct-9204	224	9	,	,	PUNCT
ct-9204	224	10	et	et	PROPN
ct-9204	224	11	al	al	PROPN
ct-9204	224	12	:	:	PUNCT
ct-9204	224	13	distinct	distinct	ADJ
ct-9204	224	14	lipid	lipid	NOUN
ct-9204	224	15	compositions	composition	NOUN
ct-9204	224	16	of	of	ADP
ct-9204	224	17	two	two	NUM
ct-9204	224	18	types	type	NOUN
ct-9204	224	19	of	of	ADP
ct-9204	224	20	human	human	ADJ
ct-9204	224	21	prostasomes	prostasome	NOUN
ct-9204	224	22	.	.	PUNCT
ct-9204	225	1	proteomics	proteomic	NOUN
ct-9204	225	2	2013;13:1660	2013;13:1660	NOUN
ct-9204	225	3	-	-	SYM
ct-9204	225	4	1666	1666	NUM
ct-9204	225	5	.	.	PUNCT
ct-9204	226	1	48	48	NUM
ct-9204	226	2	.	.	PUNCT
ct-9204	227	1	arvidson	arvidson	NOUN
ct-9204	227	2	g	g	PROPN
ct-9204	227	3	,	,	PUNCT
ct-9204	227	4	ronquist	ronquist	NOUN
ct-9204	227	5	g	g	PROPN
ct-9204	227	6	,	,	PUNCT
ct-9204	227	7	wikander	wikander	NOUN
ct-9204	227	8	g	g	PROPN
ct-9204	227	9	,	,	PUNCT
ct-9204	227	10	et	et	PROPN
ct-9204	227	11	al	al	PROPN
ct-9204	227	12	:	:	PUNCT
ct-9204	227	13	human	human	ADJ
ct-9204	227	14	prostasome	prostasome	NOUN
ct-9204	227	15	membranes	membrane	NOUN
ct-9204	227	16	exhibit	exhibit	VERB
ct-9204	227	17	very	very	ADV
ct-9204	227	18	high	high	ADJ
ct-9204	227	19	cholesterol	cholesterol	NOUN
ct-9204	227	20	/	/	SYM
ct-9204	227	21	phospholipid	phospholipid	NOUN
ct-9204	227	22	ratios	ratio	NOUN
ct-9204	227	23	yielding	yield	VERB
ct-9204	227	24	high	high	ADJ
ct-9204	227	25	molecular	molecular	ADJ
ct-9204	227	26	ordering	ordering	NOUN
ct-9204	227	27	.	.	PUNCT
ct-9204	228	1	bba	bba	PROPN
ct-9204	228	2	biomembranes	biomembrane	VERB
ct-9204	228	3	1989;984:167	1989;984:167	NUM
ct-9204	228	4	-	-	SYM
ct-9204	228	5	173	173	NUM
ct-9204	228	6	.	.	NOUN
ct-9204	228	7	49	49	NUM
ct-9204	228	8	.	.	PUNCT
ct-9204	229	1	burden	burden	PROPN
ct-9204	229	2	hp	hp	PROPN
ct-9204	229	3	,	,	PUNCT
ct-9204	229	4	holmes	holmes	PROPN
ct-9204	229	5	ch	ch	PROPN
ct-9204	229	6	,	,	PUNCT
ct-9204	229	7	persad	persad	ADJ
ct-9204	229	8	r	r	NOUN
ct-9204	229	9	,	,	PUNCT
ct-9204	229	10	et	et	PROPN
ct-9204	229	11	al	al	PROPN
ct-9204	229	12	:	:	PUNCT
ct-9204	229	13	prostasomes	prostasome	NOUN
ct-9204	229	14	—	—	PUNCT
ct-9204	229	15	their	their	PRON
ct-9204	229	16	effects	effect	NOUN
ct-9204	229	17	on	on	ADP
ct-9204	229	18	human	human	ADJ
ct-9204	229	19	male	male	ADJ
ct-9204	229	20	reproduction	reproduction	NOUN
ct-9204	229	21	and	and	CCONJ
ct-9204	229	22	fertility	fertility	NOUN
ct-9204	229	23	.	.	PUNCT
ct-9204	230	1	hum	hum	PROPN
ct-9204	230	2	reprod	reprod	PROPN
ct-9204	230	3	update	update	VERB
ct-9204	230	4	2005;12:283	2005;12:283	NOUN
ct-9204	230	5	-	-	SYM
ct-9204	230	6	292	292	NUM
ct-9204	230	7	.	.	PUNCT
ct-9204	231	1	50	50	NUM
ct-9204	231	2	.	.	PUNCT
ct-9204	232	1	frenette	frenette	NOUN
ct-9204	232	2	g	g	PROPN
ct-9204	232	3	,	,	PUNCT
ct-9204	232	4	sullivan	sullivan	NOUN
ct-9204	232	5	r	r	NOUN
ct-9204	232	6	:	:	PUNCT
ct-9204	232	7	prostasome‐like	prostasome‐like	SCONJ
ct-9204	232	8	particles	particle	NOUN
ct-9204	232	9	are	be	AUX
ct-9204	232	10	involved	involve	VERB
ct-9204	232	11	in	in	ADP
ct-9204	232	12	the	the	DET
ct-9204	232	13	transfer	transfer	NOUN
ct-9204	232	14	of	of	ADP
ct-9204	232	15	p25b	p25b	NOUN
ct-9204	232	16	from	from	ADP
ct-9204	232	17	the	the	DET
ct-9204	232	18	bovine	bovine	ADJ
ct-9204	232	19	epididymal	epididymal	ADJ
ct-9204	232	20	fluid	fluid	NOUN
ct-9204	232	21	to	to	ADP
ct-9204	232	22	the	the	DET
ct-9204	232	23	sperm	sperm	NOUN
ct-9204	232	24	surface	surface	NOUN
ct-9204	232	25	.	.	PUNCT
ct-9204	233	1	mol	mol	PROPN
ct-9204	233	2	reprod	reprod	PROPN
ct-9204	233	3	dev	dev	PROPN
ct-9204	233	4	2001;59:115	2001;59:115	PROPN
ct-9204	233	5	-	-	SYM
ct-9204	233	6	121	121	NUM
ct-9204	233	7	.	.	PUNCT
ct-9204	234	1	51	51	NUM
ct-9204	234	2	.	.	PUNCT
ct-9204	235	1	pons‐rejraji	pons‐rejraji	PROPN
ct-9204	235	2	h	h	NOUN
ct-9204	235	3	,	,	PUNCT
ct-9204	235	4	artonne	artonne	NOUN
ct-9204	235	5	c	c	NOUN
ct-9204	235	6	,	,	PUNCT
ct-9204	235	7	sion	sion	PROPN
ct-9204	235	8	b	b	NUM
ct-9204	235	9	,	,	PUNCT
ct-9204	235	10	et	et	PROPN
ct-9204	235	11	al	al	PROPN
ct-9204	235	12	:	:	PUNCT
ct-9204	235	13	prostasomes	prostasome	NOUN
ct-9204	235	14	:	:	PUNCT
ct-9204	235	15	inhibitors	inhibitor	NOUN
ct-9204	235	16	of	of	ADP
ct-9204	235	17	capacitation	capacitation	NOUN
ct-9204	235	18	and	and	CCONJ
ct-9204	235	19	modulators	modulator	NOUN
ct-9204	235	20	of	of	ADP
ct-9204	235	21	cellular	cellular	ADJ
ct-9204	235	22	signalling	signal	VERB
ct-9204	235	23	in	in	ADP
ct-9204	235	24	human	human	ADJ
ct-9204	235	25	sperm	sperm	NOUN
ct-9204	235	26	.	.	PUNCT
ct-9204	236	1	int	int	PROPN
ct-9204	237	1	j	j	PROPN
ct-9204	237	2	androl	androl	PROPN
ct-9204	237	3	2011;34:568	2011;34:568	PROPN
ct-9204	237	4	-	-	PUNCT
ct-9204	237	5	580	580	NUM
ct-9204	237	6	.	.	PUNCT
ct-9204	237	7	52	52	NUM
ct-9204	237	8	.	.	PUNCT
ct-9204	237	9	carlini	carlini	PROPN
ct-9204	237	10	e	e	PROPN
ct-9204	237	11	,	,	PUNCT
ct-9204	237	12	palmerini	palmerini	PROPN
ct-9204	237	13	ca	can	AUX
ct-9204	237	14	,	,	PUNCT
ct-9204	237	15	cosmi	cosmi	NOUN
ct-9204	237	16	ev	ev	PROPN
ct-9204	237	17	,	,	PUNCT
ct-9204	237	18	et	et	PROPN
ct-9204	237	19	al	al	PROPN
ct-9204	237	20	:	:	PUNCT
ct-9204	237	21	fusion	fusion	NOUN
ct-9204	237	22	of	of	ADP
ct-9204	237	23	sperm	sperm	NOUN
ct-9204	237	24	with	with	ADP
ct-9204	237	25	prostasomes	prostasome	NOUN
ct-9204	237	26	:	:	PUNCT
ct-9204	237	27	effects	effect	NOUN
ct-9204	237	28	on	on	ADP
ct-9204	237	29	membrane	membrane	NOUN
ct-9204	237	30	fluidity	fluidity	NOUN
ct-9204	237	31	.	.	PUNCT
ct-9204	238	1	arch	arch	ADJ
ct-9204	238	2	biochem	biochem	PROPN
ct-9204	238	3	biophys	biophy	VERB
ct-9204	238	4	1997;343:6	1997;343:6	PROPN
ct-9204	238	5	-	-	SYM
ct-9204	238	6	12	12	NUM
ct-9204	238	7	.	.	PUNCT
ct-9204	239	1	53	53	NUM
ct-9204	239	2	.	.	PUNCT
ct-9204	239	3	tarazona	tarazona	PROPN
ct-9204	239	4	r	r	PROPN
ct-9204	239	5	,	,	PUNCT
ct-9204	239	6	delgado	delgado	NOUN
ct-9204	239	7	e	e	NOUN
ct-9204	239	8	,	,	PUNCT
ct-9204	239	9	guarnizo	guarnizo	PROPN
ct-9204	239	10	m	m	PROPN
ct-9204	239	11	,	,	PUNCT
ct-9204	239	12	et	et	PROPN
ct-9204	239	13	al	al	PROPN
ct-9204	239	14	:	:	PUNCT
ct-9204	239	15	human	human	ADJ
ct-9204	239	16	prostasomes	prostasome	NOUN
ct-9204	239	17	express	express	VERB
ct-9204	239	18	cd48	cd48	PROPN
ct-9204	239	19	and	and	CCONJ
ct-9204	239	20	interfere	interfere	VERB
ct-9204	239	21	with	with	ADP
ct-9204	239	22	nk	nk	PROPN
ct-9204	239	23	cell	cell	NOUN
ct-9204	239	24	function	function	NOUN
ct-9204	239	25	.	.	PUNCT
ct-9204	240	1	immunobiology	immunobiology	NOUN
ct-9204	240	2	2011;216:41	2011;216:41	NUM
ct-9204	240	3	-	-	SYM
ct-9204	240	4	46	46	NUM
ct-9204	240	5	.	.	PUNCT
ct-9204	240	6	54	54	NUM
ct-9204	240	7	.	.	PUNCT
ct-9204	241	1	fereshteh	fereshteh	PROPN
ct-9204	241	2	z	z	PROPN
ct-9204	241	3	,	,	PUNCT
ct-9204	241	4	bathala	bathala	PROPN
ct-9204	241	5	p	p	X
ct-9204	241	6	,	,	PUNCT
ct-9204	241	7	galileo	galileo	X
ct-9204	241	8	ds	ds	PROPN
ct-9204	241	9	,	,	PUNCT
ct-9204	241	10	et	et	PROPN
ct-9204	241	11	al	al	PROPN
ct-9204	241	12	:	:	PUNCT
ct-9204	241	13	detection	detection	NOUN
ct-9204	241	14	of	of	ADP
ct-9204	241	15	extracellular	extracellular	ADJ
ct-9204	241	16	vesicles	vesicle	NOUN
ct-9204	241	17	in	in	ADP
ct-9204	241	18	the	the	DET
ct-9204	241	19	mouse	mouse	NOUN
ct-9204	241	20	vaginal	vaginal	ADJ
ct-9204	241	21	fluid	fluid	NOUN
ct-9204	241	22	:	:	PUNCT
ct-9204	241	23	their	their	PRON
ct-9204	241	24	delivery	delivery	NOUN
ct-9204	241	25	of	of	ADP
ct-9204	241	26	sperm	sperm	NOUN
ct-9204	241	27	proteins	protein	NOUN
ct-9204	241	28	that	that	PRON
ct-9204	241	29	stimulate	stimulate	VERB
ct-9204	241	30	capacitation	capacitation	NOUN
ct-9204	241	31	and	and	CCONJ
ct-9204	241	32	modulate	modulate	VERB
ct-9204	241	33	fertility	fertility	NOUN
ct-9204	241	34	.	.	PUNCT
ct-9204	242	1	j	j	PROPN
ct-9204	242	2	cell	cell	PROPN
ct-9204	242	3	physiol	physiol	PROPN
ct-9204	242	4	2019;234:12745	2019;234:12745	NUM
ct-9204	242	5	-	-	SYM
ct-9204	242	6	12756	12756	NUM
ct-9204	242	7	.	.	PUNCT
ct-9204	243	1	55	55	NUM
ct-9204	243	2	.	.	PUNCT
ct-9204	244	1	o'neil	o'neil	PROPN
ct-9204	244	2	ev	ev	PROPN
ct-9204	244	3	,	,	PUNCT
ct-9204	244	4	burns	burn	NOUN
ct-9204	244	5	gw	gw	PROPN
ct-9204	244	6	,	,	PUNCT
ct-9204	244	7	spencer	spencer	PROPN
ct-9204	244	8	te	te	PROPN
ct-9204	244	9	:	:	PUNCT
ct-9204	244	10	extracellular	extracellular	ADJ
ct-9204	244	11	vesicles	vesicle	NOUN
ct-9204	244	12	:	:	PUNCT
ct-9204	244	13	novel	novel	ADJ
ct-9204	244	14	regulators	regulator	NOUN
ct-9204	244	15	of	of	ADP
ct-9204	244	16	conceptus	conceptus	NOUN
ct-9204	244	17	-	-	PUNCT
ct-9204	244	18	uterine	uterine	ADJ
ct-9204	244	19	interactions	interaction	NOUN
ct-9204	244	20	?	?	PUNCT
ct-9204	245	1	theriogenology	theriogenology	NOUN
ct-9204	245	2	2020	2020	NUM
ct-9204	245	3	;	;	PUNCT
ct-9204	245	4	in	in	ADP
ct-9204	245	5	press	press	NOUN
ct-9204	245	6	.	.	PUNCT
ct-9204	246	1	56	56	NUM
ct-9204	246	2	.	.	X
ct-9204	246	3	kurian	kurian	PROPN
ct-9204	246	4	nk	nk	PROPN
ct-9204	246	5	,	,	PUNCT
ct-9204	246	6	modi	modi	PROPN
ct-9204	246	7	d	d	NOUN
ct-9204	246	8	:	:	PUNCT
ct-9204	246	9	extracellular	extracellular	ADJ
ct-9204	246	10	vesicle	vesicle	NOUN
ct-9204	246	11	mediated	mediate	VERB
ct-9204	246	12	embryo	embryo	NOUN
ct-9204	246	13	-	-	PUNCT
ct-9204	246	14	endometrial	endometrial	ADJ
ct-9204	246	15	cross	cross	NOUN
ct-9204	246	16	talk	talk	NOUN
ct-9204	246	17	during	during	ADP
ct-9204	246	18	implantation	implantation	NOUN
ct-9204	246	19	and	and	CCONJ
ct-9204	246	20	in	in	ADP
ct-9204	246	21	pregnancy	pregnancy	NOUN
ct-9204	246	22	.	.	PUNCT
ct-9204	247	1	j	j	PROPN
ct-9204	247	2	assist	assist	VERB
ct-9204	247	3	reprod	reprod	PROPN
ct-9204	247	4	genet	genet	PROPN
ct-9204	247	5	2019;36:189	2019;36:189	PROPN
ct-9204	247	6	-	-	SYM
ct-9204	247	7	198	198	NUM
ct-9204	247	8	.	.	PUNCT
ct-9204	248	1	57	57	NUM
ct-9204	248	2	.	.	PUNCT
ct-9204	249	1	tesfaye	tesfaye	PROPN
ct-9204	249	2	d	d	PROPN
ct-9204	249	3	,	,	PUNCT
ct-9204	249	4	hailay	hailay	PROPN
ct-9204	249	5	t	t	PROPN
ct-9204	249	6	,	,	PUNCT
ct-9204	249	7	salilew	salilew	NOUN
ct-9204	249	8	-	-	PUNCT
ct-9204	249	9	wondim	wondim	PROPN
ct-9204	249	10	d	d	PROPN
ct-9204	249	11	,	,	PUNCT
ct-9204	249	12	et	et	PROPN
ct-9204	249	13	al	al	PROPN
ct-9204	249	14	:	:	PUNCT
ct-9204	249	15	extracellular	extracellular	ADJ
ct-9204	249	16	vesicle	vesicle	NOUN
ct-9204	249	17	mediated	mediate	VERB
ct-9204	249	18	molecular	molecular	ADJ
ct-9204	249	19	signaling	signal	VERB
ct-9204	249	20	in	in	ADP
ct-9204	249	21	ovarian	ovarian	ADJ
ct-9204	249	22	follicle	follicle	NOUN
ct-9204	249	23	:	:	PUNCT
ct-9204	249	24	implication	implication	NOUN
ct-9204	249	25	for	for	ADP
ct-9204	249	26	oocyte	oocyte	ADJ
ct-9204	249	27	developmental	developmental	ADJ
ct-9204	249	28	competence	competence	NOUN
ct-9204	249	29	.	.	PUNCT
ct-9204	250	1	theriogenology	theriogenology	NOUN
ct-9204	250	2	2020	2020	NUM
ct-9204	250	3	;	;	PUNCT
ct-9204	250	4	in	in	ADP
ct-9204	250	5	press	press	NOUN
ct-9204	250	6	.	.	PUNCT
ct-9204	251	1	clinical	clinical	ADJ
ct-9204	251	2	theriogenology	theriogenology	NOUN
ct-9204	251	3	•	•	NOUN
ct-9204	251	4	volume	volume	NOUN
ct-9204	251	5	12	12	NUM
ct-9204	251	6	number	number	NOUN
ct-9204	251	7	2	2	NUM
ct-9204	251	8	•	•	NOUN
ct-9204	251	9	june	june	PROPN
ct-9204	251	10	202098	202098	NUM
ct-9204	251	11	58	58	NUM
ct-9204	251	12	.	.	PUNCT
ct-9204	252	1	di	di	PROPN
ct-9204	252	2	pietro	pietro	PROPN
ct-9204	252	3	c	c	PROPN
ct-9204	252	4	:	:	PUNCT
ct-9204	252	5	exosome	exosome	NOUN
ct-9204	252	6	-	-	PUNCT
ct-9204	252	7	mediated	mediate	VERB
ct-9204	252	8	communication	communication	NOUN
ct-9204	252	9	in	in	ADP
ct-9204	252	10	the	the	DET
ct-9204	252	11	ovarian	ovarian	ADJ
ct-9204	252	12	follicle	follicle	NOUN
ct-9204	252	13	.	.	PUNCT
ct-9204	253	1	j	j	PROPN
ct-9204	253	2	assist	assist	VERB
ct-9204	253	3	reprod	reprod	PROPN
ct-9204	253	4	genet	genet	PROPN
ct-9204	253	5	2016;33:303	2016;33:303	PROPN
ct-9204	253	6	-	-	SYM
ct-9204	253	7	311	311	NUM
ct-9204	253	8	.	.	PUNCT
ct-9204	253	9	59	59	NUM
ct-9204	253	10	.	.	PUNCT
ct-9204	253	11	giacomini	giacomini	PROPN
ct-9204	253	12	e	e	PROPN
ct-9204	253	13	,	,	PUNCT
ct-9204	253	14	alleva	alleva	PROPN
ct-9204	253	15	e	e	PROPN
ct-9204	253	16	,	,	PUNCT
ct-9204	253	17	fornelli	fornelli	NOUN
ct-9204	253	18	g	g	NOUN
ct-9204	253	19	,	,	PUNCT
ct-9204	253	20	et	et	PROPN
ct-9204	253	21	al	al	PROPN
ct-9204	253	22	:	:	PUNCT
ct-9204	253	23	embryonic	embryonic	ADJ
ct-9204	253	24	extracellular	extracellular	ADJ
ct-9204	253	25	vesicles	vesicle	NOUN
ct-9204	253	26	as	as	ADP
ct-9204	253	27	informers	informer	NOUN
ct-9204	253	28	to	to	ADP
ct-9204	253	29	the	the	DET
ct-9204	253	30	immune	immune	ADJ
ct-9204	253	31	cells	cell	NOUN
ct-9204	253	32	at	at	ADP
ct-9204	253	33	the	the	DET
ct-9204	253	34	maternal	maternal	ADJ
ct-9204	253	35	–	–	PUNCT
ct-9204	253	36	fetal	fetal	ADJ
ct-9204	253	37	interface	interface	NOUN
ct-9204	253	38	.	.	PUNCT
ct-9204	254	1	clin	clin	PROPN
ct-9204	254	2	exp	exp	PROPN
ct-9204	254	3	immunol	immunol	PROPN
ct-9204	254	4	2019;198:15	2019;198:15	NUM
ct-9204	254	5	-	-	SYM
ct-9204	254	6	23	23	NUM
ct-9204	254	7	.	.	PUNCT
ct-9204	255	1	60	60	NUM
ct-9204	255	2	.	.	PUNCT
ct-9204	256	1	blázquez	blázquez	NOUN
ct-9204	256	2	r	r	NOUN
ct-9204	256	3	,	,	PUNCT
ct-9204	256	4	sánchez	sánchez	NOUN
ct-9204	256	5	-	-	PUNCT
ct-9204	256	6	margallo	margallo	PROPN
ct-9204	256	7	fm	fm	PROPN
ct-9204	256	8	,	,	PUNCT
ct-9204	256	9	álvarez	álvarez	NOUN
ct-9204	256	10	v	v	PROPN
ct-9204	256	11	,	,	PUNCT
ct-9204	256	12	et	et	PROPN
ct-9204	256	13	al	al	PROPN
ct-9204	256	14	:	:	PUNCT
ct-9204	256	15	murine	murine	ADJ
ct-9204	256	16	embryos	embryo	NOUN
ct-9204	256	17	exposed	expose	VERB
ct-9204	256	18	to	to	ADP
ct-9204	256	19	human	human	ADJ
ct-9204	256	20	endometrial	endometrial	ADJ
ct-9204	256	21	mscs	msc	NOUN
ct-9204	256	22	-	-	PUNCT
ct-9204	256	23	derived	derive	VERB
ct-9204	256	24	extracellular	extracellular	ADJ
ct-9204	256	25	vesicles	vesicle	NOUN
ct-9204	256	26	exhibit	exhibit	VERB
ct-9204	256	27	higher	high	ADJ
ct-9204	256	28	vegf	vegf	PROPN
ct-9204	256	29	/	/	SYM
ct-9204	256	30	pdgf	pdgf	PROPN
ct-9204	256	31	aa	aa	PROPN
ct-9204	256	32	release	release	NOUN
ct-9204	256	33	,	,	PUNCT
ct-9204	256	34	increased	increase	VERB
ct-9204	256	35	blastomere	blastomere	ADJ
ct-9204	256	36	count	count	NOUN
ct-9204	256	37	and	and	CCONJ
ct-9204	256	38	hatching	hatch	VERB
ct-9204	256	39	rates	rate	NOUN
ct-9204	256	40	.	.	PUNCT
ct-9204	257	1	plos	plos	PROPN
ct-9204	257	2	one	one	NUM
ct-9204	257	3	2018	2018	NUM
ct-9204	257	4	;	;	PUNCT
ct-9204	257	5	13	13	NUM
ct-9204	257	6	:	:	PUNCT
ct-9204	257	7	e0196080	e0196080	NOUN
ct-9204	257	8	.	.	NOUN
ct-9204	257	9	61	61	NUM
ct-9204	257	10	.	.	PUNCT
ct-9204	257	11	de	de	PROPN
ct-9204	257	12	amm	amm	PROPN
ct-9204	257	13	ferraz	ferraz	PROPN
ct-9204	257	14	m	m	PROPN
ct-9204	257	15	,	,	PUNCT
ct-9204	257	16	carothers	carother	VERB
ct-9204	257	17	a	a	PRON
ct-9204	257	18	,	,	PUNCT
ct-9204	257	19	dahal	dahal	NOUN
ct-9204	257	20	r	r	NOUN
ct-9204	257	21	,	,	PUNCT
ct-9204	257	22	et	et	PROPN
ct-9204	257	23	al	al	PROPN
ct-9204	257	24	:	:	PUNCT
ct-9204	257	25	oviductal	oviductal	ADJ
ct-9204	257	26	extracellular	extracellular	ADJ
ct-9204	257	27	vesicles	vesicle	NOUN
ct-9204	257	28	interact	interact	VERB
ct-9204	257	29	with	with	ADP
ct-9204	257	30	the	the	DET
ct-9204	257	31	spermatozoon	spermatozoon	NOUN
ct-9204	257	32	’s	’s	PART
ct-9204	257	33	head	head	NOUN
ct-9204	257	34	and	and	CCONJ
ct-9204	257	35	mid	mid	NOUN
ct-9204	257	36	-	-	NOUN
ct-9204	257	37	piece	piece	NOUN
ct-9204	257	38	and	and	CCONJ
ct-9204	257	39	improves	improve	VERB
ct-9204	257	40	its	its	PRON
ct-9204	257	41	motility	motility	NOUN
ct-9204	257	42	and	and	CCONJ
ct-9204	257	43	fertilizing	fertilize	VERB
ct-9204	257	44	ability	ability	NOUN
ct-9204	257	45	in	in	ADP
ct-9204	257	46	the	the	DET
ct-9204	257	47	domestic	domestic	ADJ
ct-9204	257	48	cat	cat	NOUN
ct-9204	257	49	.	.	PUNCT
ct-9204	258	1	sci	sci	PROPN
ct-9204	258	2	rep	rep	PROPN
ct-9204	258	3	2019;9:1	2019;9:1	PROPN
ct-9204	258	4	-	-	PUNCT
ct-9204	258	5	12	12	NUM
ct-9204	258	6	.	.	PUNCT
ct-9204	259	1	62	62	NUM
ct-9204	259	2	.	.	PUNCT
ct-9204	260	1	franchi	franchi	PROPN
ct-9204	260	2	a	a	PROPN
ct-9204	260	3	,	,	PUNCT
ct-9204	260	4	moreno	moreno	NOUN
ct-9204	260	5	-	-	PUNCT
ct-9204	260	6	irusta	irusta	PROPN
ct-9204	260	7	a	a	PRON
ct-9204	260	8	,	,	PUNCT
ct-9204	260	9	domínguez	domínguez	NOUN
ct-9204	260	10	em	em	PRON
ct-9204	260	11	,	,	PUNCT
ct-9204	260	12	et	et	PROPN
ct-9204	260	13	al	al	PROPN
ct-9204	260	14	:	:	PUNCT
ct-9204	260	15	extracellular	extracellular	ADJ
ct-9204	260	16	vesicles	vesicle	NOUN
ct-9204	260	17	from	from	ADP
ct-9204	260	18	oviductal	oviductal	ADJ
ct-9204	260	19	isthmus	isthmus	NOUN
ct-9204	260	20	and	and	CCONJ
ct-9204	260	21	ampulla	ampulla	NOUN
ct-9204	260	22	stimulate	stimulate	VERB
ct-9204	260	23	the	the	DET
ct-9204	260	24	induced	induced	ADJ
ct-9204	260	25	acrosome	acrosome	NOUN
ct-9204	260	26	reaction	reaction	NOUN
ct-9204	260	27	and	and	CCONJ
ct-9204	260	28	signaling	signal	VERB
ct-9204	260	29	events	event	NOUN
ct-9204	260	30	associated	associate	VERB
ct-9204	260	31	with	with	ADP
ct-9204	260	32	capacitation	capacitation	NOUN
ct-9204	260	33	in	in	ADP
ct-9204	260	34	bovine	bovine	ADJ
ct-9204	260	35	spermatozoa	spermatozoon	NOUN
ct-9204	260	36	.	.	PUNCT
ct-9204	261	1	j	j	PROPN
ct-9204	261	2	cell	cell	NOUN
ct-9204	261	3	biochem	biochem	NOUN
ct-9204	261	4	2020;121:2877	2020;121:2877	NUM
ct-9204	261	5	-	-	SYM
ct-9204	261	6	2888	2888	NUM
ct-9204	261	7	.	.	PUNCT
ct-9204	262	1	63	63	NUM
ct-9204	262	2	.	.	PUNCT
ct-9204	263	1	bathala	bathala	PROPN
ct-9204	263	2	p	p	NOUN
ct-9204	263	3	,	,	PUNCT
ct-9204	263	4	fereshteh	fereshteh	PROPN
ct-9204	263	5	z	z	PROPN
ct-9204	263	6	,	,	PUNCT
ct-9204	263	7	li	li	PROPN
ct-9204	263	8	k	k	PROPN
ct-9204	263	9	,	,	PUNCT
ct-9204	263	10	et	et	PROPN
ct-9204	263	11	al	al	PROPN
ct-9204	263	12	:	:	PUNCT
ct-9204	263	13	oviductal	oviductal	ADJ
ct-9204	263	14	extracellular	extracellular	ADJ
ct-9204	263	15	vesicles	vesicle	NOUN
ct-9204	263	16	(	(	PUNCT
ct-9204	263	17	oviductosomes	oviductosomes	ADJ
ct-9204	263	18	,	,	PUNCT
ct-9204	263	19	ovs	ovs	NOUN
ct-9204	263	20	)	)	PUNCT
ct-9204	263	21	are	be	AUX
ct-9204	263	22	conserved	conserve	VERB
ct-9204	263	23	in	in	ADP
ct-9204	263	24	humans	human	NOUN
ct-9204	263	25	:	:	PUNCT
ct-9204	263	26	murine	murine	ADJ
ct-9204	263	27	ovs	ovs	NOUN
ct-9204	263	28	play	play	VERB
ct-9204	263	29	a	a	DET
ct-9204	263	30	pivotal	pivotal	ADJ
ct-9204	263	31	role	role	NOUN
ct-9204	263	32	in	in	ADP
ct-9204	263	33	sperm	sperm	NOUN
ct-9204	263	34	capacitation	capacitation	NOUN
ct-9204	263	35	and	and	CCONJ
ct-9204	263	36	fertility	fertility	NOUN
ct-9204	263	37	.	.	PUNCT
ct-9204	264	1	mol	mol	ADP
ct-9204	264	2	hum	hum	X
ct-9204	264	3	reprod	reprod	PROPN
ct-9204	264	4	2018;24:143	2018;24:143	X
ct-9204	264	5	-	-	SYM
ct-9204	264	6	157	157	NUM
ct-9204	264	7	.	.	PUNCT
ct-9204	265	1	64	64	NUM
ct-9204	265	2	.	.	PUNCT
ct-9204	266	1	alcântara	alcântara	PROPN
ct-9204	266	2	-	-	PUNCT
ct-9204	266	3	neto	neto	NOUN
ct-9204	266	4	a	a	DET
ct-9204	266	5	,	,	PUNCT
ct-9204	266	6	fernandez	fernandez	NOUN
ct-9204	266	7	-	-	PUNCT
ct-9204	266	8	rufete	rufete	PROPN
ct-9204	266	9	m	m	PROPN
ct-9204	266	10	,	,	PUNCT
ct-9204	266	11	corbin	corbin	PROPN
ct-9204	266	12	e	e	PROPN
ct-9204	266	13	,	,	PUNCT
ct-9204	266	14	et	et	PROPN
ct-9204	266	15	al	al	PROPN
ct-9204	266	16	:	:	PUNCT
ct-9204	266	17	oviduct	oviduct	NOUN
ct-9204	266	18	fluid	fluid	ADJ
ct-9204	266	19	extracellular	extracellular	ADJ
ct-9204	266	20	vesicles	vesicle	NOUN
ct-9204	266	21	regulate	regulate	VERB
ct-9204	266	22	polyspermy	polyspermy	ADJ
ct-9204	266	23	during	during	ADP
ct-9204	266	24	porcine	porcine	NOUN
ct-9204	266	25	in	in	ADP
ct-9204	266	26	vitro	vitro	X
ct-9204	266	27	fertilisation	fertilisation	NOUN
ct-9204	266	28	.	.	PUNCT
ct-9204	267	1	reprod	reprod	PROPN
ct-9204	267	2	fertil	fertil	AUX
ct-9204	267	3	dev	dev	PROPN
ct-9204	267	4	2019;32:409	2019;32:409	NOUN
ct-9204	267	5	-	-	SYM
ct-9204	267	6	418	418	NUM
ct-9204	267	7	.	.	PUNCT
ct-9204	268	1	65	65	NUM
ct-9204	268	2	.	.	PUNCT
ct-9204	269	1	qu	qu	PROPN
ct-9204	269	2	p	p	PROPN
ct-9204	269	3	,	,	PUNCT
ct-9204	269	4	zhao	zhao	PROPN
ct-9204	269	5	y	y	PROPN
ct-9204	269	6	,	,	PUNCT
ct-9204	269	7	wang	wang	PROPN
ct-9204	269	8	r	r	PROPN
ct-9204	269	9	,	,	PUNCT
ct-9204	269	10	et	et	PROPN
ct-9204	269	11	al	al	PROPN
ct-9204	269	12	:	:	PUNCT
ct-9204	269	13	extracellular	extracellular	ADJ
ct-9204	269	14	vesicles	vesicle	NOUN
ct-9204	269	15	derived	derive	VERB
ct-9204	269	16	from	from	ADP
ct-9204	269	17	donor	donor	NOUN
ct-9204	269	18	oviduct	oviduct	NOUN
ct-9204	269	19	fluid	fluid	NOUN
ct-9204	269	20	improved	improve	VERB
ct-9204	269	21	birth	birth	NOUN
ct-9204	269	22	rates	rate	NOUN
ct-9204	269	23	after	after	ADP
ct-9204	269	24	embryo	embryo	NOUN
ct-9204	269	25	transfer	transfer	NOUN
ct-9204	269	26	in	in	ADP
ct-9204	269	27	mice	mouse	NOUN
ct-9204	269	28	.	.	PUNCT
ct-9204	270	1	reprod	reprod	PROPN
ct-9204	270	2	fertil	fertil	PROPN
ct-9204	270	3	dev	dev	PROPN
ct-9204	270	4	2019;31:324	2019;31:324	PROPN
ct-9204	270	5	-	-	PUNCT
ct-9204	270	6	332	332	NUM
ct-9204	270	7	.	.	PUNCT
ct-9204	271	1	66	66	NUM
ct-9204	271	2	.	.	PUNCT
ct-9204	271	3	de	de	PROPN
ct-9204	271	4	ávila	ávila	PROPN
ct-9204	271	5	acfcm	acfcm	PROPN
ct-9204	271	6	,	,	PUNCT
ct-9204	271	7	bridi	bridi	NOUN
ct-9204	271	8	a	a	PRON
ct-9204	271	9	,	,	PUNCT
ct-9204	271	10	andrade	andrade	PROPN
ct-9204	271	11	gm	gm	PROPN
ct-9204	271	12	,	,	PUNCT
ct-9204	271	13	et	et	PROPN
ct-9204	271	14	al	al	PROPN
ct-9204	271	15	:	:	PUNCT
ct-9204	271	16	estrous	estrous	ADJ
ct-9204	271	17	cycle	cycle	NOUN
ct-9204	271	18	impacts	impact	VERB
ct-9204	271	19	microrna	microrna	PROPN
ct-9204	271	20	content	content	PROPN
ct-9204	271	21	in	in	ADP
ct-9204	271	22	extracellular	extracellular	ADJ
ct-9204	271	23	vesicles	vesicle	NOUN
ct-9204	271	24	that	that	PRON
ct-9204	271	25	modulate	modulate	VERB
ct-9204	271	26	bovine	bovine	NOUN
ct-9204	271	27	cumulus	cumulus	NOUN
ct-9204	271	28	cell	cell	NOUN
ct-9204	271	29	transcripts	transcript	NOUN
ct-9204	271	30	during	during	ADP
ct-9204	271	31	in	in	ADP
ct-9204	271	32	vitro	vitro	X
ct-9204	271	33	maturation†.	maturation†.	X
ct-9204	271	34	biol	biol	NOUN
ct-9204	271	35	reprod	reprod	NOUN
ct-9204	271	36	2019;102:362	2019;102:362	NUM
ct-9204	271	37	-	-	SYM
ct-9204	271	38	375	375	NUM
ct-9204	271	39	.	.	PUNCT
ct-9204	271	40	67	67	NUM
ct-9204	271	41	.	.	PUNCT
ct-9204	272	1	hung	hung	PROPN
ct-9204	272	2	w	w	PROPN
ct-9204	272	3	-	-	PUNCT
ct-9204	272	4	t	t	PROPN
ct-9204	272	5	,	,	PUNCT
ct-9204	272	6	navakanitworakul	navakanitworakul	NOUN
ct-9204	272	7	r	r	NOUN
ct-9204	272	8	,	,	PUNCT
ct-9204	272	9	khan	khan	PROPN
ct-9204	272	10	t	t	PROPN
ct-9204	272	11	,	,	PUNCT
ct-9204	272	12	et	et	PROPN
ct-9204	272	13	al	al	PROPN
ct-9204	272	14	:	:	PUNCT
ct-9204	272	15	stage	stage	NOUN
ct-9204	272	16	-	-	PUNCT
ct-9204	272	17	specific	specific	ADJ
ct-9204	272	18	follicular	follicular	ADJ
ct-9204	272	19	extracellular	extracellular	ADJ
ct-9204	272	20	vesicle	vesicle	NOUN
ct-9204	272	21	uptake	uptake	NOUN
ct-9204	272	22	and	and	CCONJ
ct-9204	272	23	regulation	regulation	NOUN
ct-9204	272	24	of	of	ADP
ct-9204	272	25	bovine	bovine	ADJ
ct-9204	272	26	granulosa	granulosa	PROPN
ct-9204	272	27	cell	cell	NOUN
ct-9204	272	28	proliferation	proliferation	NOUN
ct-9204	272	29	.	.	PUNCT
ct-9204	273	1	biol	biol	PROPN
ct-9204	273	2	reprod	reprod	NOUN
ct-9204	273	3	2017;97:644	2017;97:644	PROPN
ct-9204	273	4	-	-	SYM
ct-9204	273	5	655	655	NUM
ct-9204	273	6	.	.	PUNCT
ct-9204	274	1	68	68	NUM
ct-9204	274	2	.	.	PUNCT
ct-9204	275	1	hung	hang	VERB
ct-9204	275	2	w	w	PROPN
ct-9204	275	3	-	-	PUNCT
ct-9204	275	4	t	t	PROPN
ct-9204	275	5	,	,	PUNCT
ct-9204	275	6	hong	hong	PROPN
ct-9204	275	7	x	x	SYM
ct-9204	275	8	,	,	PUNCT
ct-9204	275	9	christenson	christenson	PROPN
ct-9204	275	10	lk	lk	PROPN
ct-9204	275	11	,	,	PUNCT
ct-9204	275	12	et	et	PROPN
ct-9204	275	13	al	al	PROPN
ct-9204	275	14	:	:	PUNCT
ct-9204	275	15	extracellular	extracellular	ADJ
ct-9204	275	16	vesicles	vesicle	NOUN
ct-9204	275	17	from	from	ADP
ct-9204	275	18	bovine	bovine	ADJ
ct-9204	275	19	follicular	follicular	ADJ
ct-9204	275	20	fluid	fluid	NOUN
ct-9204	275	21	support	support	NOUN
ct-9204	275	22	cumulus	cumulus	NOUN
ct-9204	275	23	expansion	expansion	NOUN
ct-9204	275	24	.	.	PUNCT
ct-9204	276	1	biol	biol	PROPN
ct-9204	276	2	reprod	reprod	PROPN
ct-9204	276	3	2015;93:117,111	2015;93:117,111	PROPN
ct-9204	276	4	-	-	SYM
ct-9204	276	5	119	119	NUM
ct-9204	276	6	.	.	PUNCT
ct-9204	276	7	69	69	NUM
ct-9204	276	8	.	.	PUNCT
ct-9204	277	1	da	da	PROPN
ct-9204	277	2	silveira	silveira	PROPN
ct-9204	277	3	jc	jc	PROPN
ct-9204	277	4	,	,	PUNCT
ct-9204	277	5	andrade	andrade	PROPN
ct-9204	277	6	gm	gm	PROPN
ct-9204	277	7	,	,	PUNCT
ct-9204	277	8	del	del	PROPN
ct-9204	277	9	collado	collado	PROPN
ct-9204	277	10	m	m	PROPN
ct-9204	277	11	,	,	PUNCT
ct-9204	277	12	et	et	PROPN
ct-9204	277	13	al	al	PROPN
ct-9204	277	14	:	:	PUNCT
ct-9204	277	15	supplementation	supplementation	NOUN
ct-9204	277	16	with	with	ADP
ct-9204	277	17	small	small	ADJ
ct-9204	277	18	-	-	PUNCT
ct-9204	277	19	extracellular	extracellular	ADJ
ct-9204	277	20	vesicles	vesicle	NOUN
ct-9204	277	21	from	from	ADP
ct-9204	277	22	ovarian	ovarian	ADJ
ct-9204	277	23	follicular	follicular	ADJ
ct-9204	277	24	fluid	fluid	NOUN
ct-9204	277	25	during	during	ADP
ct-9204	277	26	in	in	ADP
ct-9204	277	27	vitro	vitro	X
ct-9204	277	28	production	production	NOUN
ct-9204	277	29	modulates	modulate	NOUN
ct-9204	277	30	bovine	bovine	VERB
ct-9204	277	31	embryo	embryo	NOUN
ct-9204	277	32	development	development	NOUN
ct-9204	277	33	.	.	PUNCT
ct-9204	278	1	plos	plos	PROPN
ct-9204	278	2	one	one	NUM
ct-9204	278	3	2017	2017	NUM
ct-9204	278	4	;	;	PUNCT
ct-9204	278	5	12	12	NUM
ct-9204	278	6	:	:	PUNCT
ct-9204	278	7	e0179451	e0179451	NOUN
ct-9204	278	8	.	.	PUNCT
ct-9204	279	1	70	70	NUM
ct-9204	279	2	.	.	PUNCT
ct-9204	280	1	almiñana	almiñana	PROPN
ct-9204	280	2	c	c	PROPN
ct-9204	280	3	,	,	PUNCT
ct-9204	280	4	tsikis	tsiki	VERB
ct-9204	280	5	g	g	NOUN
ct-9204	280	6	,	,	PUNCT
ct-9204	280	7	labas	labas	PROPN
ct-9204	280	8	v	v	PROPN
ct-9204	280	9	,	,	PUNCT
ct-9204	280	10	et	et	PROPN
ct-9204	280	11	al	al	PROPN
ct-9204	280	12	:	:	PUNCT
ct-9204	280	13	deciphering	decipher	VERB
ct-9204	280	14	the	the	DET
ct-9204	280	15	oviductal	oviductal	ADJ
ct-9204	280	16	extracellular	extracellular	ADJ
ct-9204	280	17	vesicles	vesicle	NOUN
ct-9204	280	18	content	content	VERB
ct-9204	280	19	across	across	ADP
ct-9204	280	20	the	the	DET
ct-9204	280	21	estrous	estrous	ADJ
ct-9204	280	22	cycle	cycle	NOUN
ct-9204	280	23	:	:	PUNCT
ct-9204	280	24	implications	implication	NOUN
ct-9204	280	25	for	for	ADP
ct-9204	280	26	the	the	DET
ct-9204	280	27	gametes	gamete	NOUN
ct-9204	280	28	-	-	PUNCT
ct-9204	280	29	oviduct	oviduct	NOUN
ct-9204	280	30	interactions	interaction	NOUN
ct-9204	280	31	and	and	CCONJ
ct-9204	280	32	the	the	DET
ct-9204	280	33	environment	environment	NOUN
ct-9204	280	34	of	of	ADP
ct-9204	280	35	the	the	DET
ct-9204	280	36	potential	potential	ADJ
ct-9204	280	37	embryo	embryo	NOUN
ct-9204	280	38	.	.	PUNCT
ct-9204	281	1	bmc	bmc	ADJ
ct-9204	281	2	genomics	genomic	NOUN
ct-9204	281	3	2018;19:622	2018;19:622	NUM
ct-9204	281	4	-	-	SYM
ct-9204	281	5	649	649	NUM
ct-9204	281	6	.	.	PUNCT
ct-9204	281	7	71	71	NUM
ct-9204	281	8	.	.	PUNCT
ct-9204	281	9	burns	burn	NOUN
ct-9204	281	10	gw	gw	PROPN
ct-9204	281	11	,	,	PUNCT
ct-9204	281	12	brooks	brooks	PROPN
ct-9204	281	13	ke	ke	PROPN
ct-9204	281	14	,	,	PUNCT
ct-9204	281	15	o’neil	o’neil	PROPN
ct-9204	281	16	ev	ev	PROPN
ct-9204	281	17	,	,	PUNCT
ct-9204	281	18	et	et	PROPN
ct-9204	281	19	al	al	PROPN
ct-9204	281	20	:	:	PUNCT
ct-9204	281	21	progesterone	progesterone	NOUN
ct-9204	281	22	effects	effect	NOUN
ct-9204	281	23	on	on	ADP
ct-9204	281	24	extracellular	extracellular	ADJ
ct-9204	281	25	vesicles	vesicle	NOUN
ct-9204	281	26	in	in	ADP
ct-9204	281	27	the	the	DET
ct-9204	281	28	sheep	sheep	NOUN
ct-9204	281	29	uterus	uterus	NOUN
ct-9204	281	30	.	.	PUNCT
ct-9204	282	1	biol	biol	PROPN
ct-9204	282	2	reprod	reprod	NOUN
ct-9204	282	3	2018;98:612	2018;98:612	ADV
ct-9204	282	4	-	-	SYM
ct-9204	282	5	622	622	NUM
ct-9204	282	6	.	.	PUNCT
ct-9204	283	1	72	72	NUM
ct-9204	283	2	.	.	PUNCT
ct-9204	283	3	greening	green	VERB
ct-9204	283	4	dw	dw	PROPN
ct-9204	283	5	,	,	PUNCT
ct-9204	283	6	nguyen	nguyen	PROPN
ct-9204	283	7	hpt	hpt	PROPN
ct-9204	283	8	,	,	PUNCT
ct-9204	283	9	elgass	elgass	PROPN
ct-9204	283	10	k	k	PROPN
ct-9204	283	11	,	,	PUNCT
ct-9204	283	12	et	et	PROPN
ct-9204	283	13	al	al	PROPN
ct-9204	283	14	:	:	PUNCT
ct-9204	283	15	human	human	ADJ
ct-9204	283	16	endometrial	endometrial	ADJ
ct-9204	283	17	exosomes	exosome	NOUN
ct-9204	283	18	contain	contain	VERB
ct-9204	283	19	hormone	hormone	NOUN
ct-9204	283	20	-	-	PUNCT
ct-9204	283	21	specific	specific	ADJ
ct-9204	283	22	cargo	cargo	NOUN
ct-9204	283	23	modulating	modulate	VERB
ct-9204	283	24	trophoblast	trophoblast	ADJ
ct-9204	283	25	adhesive	adhesive	ADJ
ct-9204	283	26	capacity	capacity	NOUN
ct-9204	283	27	:	:	PUNCT
ct-9204	283	28	insights	insight	NOUN
ct-9204	283	29	into	into	ADP
ct-9204	283	30	endometrial	endometrial	ADJ
ct-9204	283	31	-	-	PUNCT
ct-9204	283	32	embryo	embryo	NOUN
ct-9204	283	33	interactions	interaction	NOUN
ct-9204	283	34	.	.	PUNCT
ct-9204	284	1	biol	biol	PROPN
ct-9204	284	2	reprod	reprod	PROPN
ct-9204	284	3	2016	2016	NUM
ct-9204	284	4	feb;94(2):38	feb;94(2):38	PROPN
ct-9204	284	5	.	.	PUNCT
ct-9204	285	1	doi	doi	PROPN
ct-9204	285	2	:	:	PUNCT
ct-9204	285	3	10.1095	10.1095	NUM
ct-9204	285	4	/	/	SYM
ct-9204	285	5	biolreprod.115.134890	biolreprod.115.134890	NOUN
ct-9204	285	6	.	.	PUNCT
ct-9204	286	1	73	73	NUM
ct-9204	286	2	.	.	PUNCT
ct-9204	287	1	fereshteh	fereshteh	PROPN
ct-9204	287	2	z	z	PROPN
ct-9204	287	3	,	,	PUNCT
ct-9204	287	4	schmidt	schmidt	PROPN
ct-9204	287	5	sa	sa	PROPN
ct-9204	287	6	,	,	PUNCT
ct-9204	287	7	al	al	PROPN
ct-9204	287	8	-	-	ADJ
ct-9204	287	9	dossary	dossary	ADJ
ct-9204	287	10	aa	aa	NOUN
ct-9204	287	11	,	,	PUNCT
ct-9204	287	12	et	et	PROPN
ct-9204	287	13	al	al	PROPN
ct-9204	287	14	:	:	PUNCT
ct-9204	287	15	murine	murine	ADJ
ct-9204	287	16	oviductosomes	oviductosomes	ADJ
ct-9204	287	17	(	(	PUNCT
ct-9204	287	18	ovs	ovs	NOUN
ct-9204	287	19	)	)	PUNCT
ct-9204	287	20	microrna	microrna	PROPN
ct-9204	287	21	profiling	profiling	NOUN
ct-9204	287	22	during	during	ADP
ct-9204	287	23	the	the	DET
ct-9204	287	24	estrous	estrous	ADJ
ct-9204	287	25	cycle	cycle	NOUN
ct-9204	287	26	:	:	PUNCT
ct-9204	287	27	delivery	delivery	NOUN
ct-9204	287	28	of	of	ADP
ct-9204	287	29	ovs	ovs	NOUN
ct-9204	287	30	-	-	PUNCT
ct-9204	287	31	borne	bear	VERB
ct-9204	287	32	micrornas	microrna	NOUN
ct-9204	287	33	to	to	AUX
ct-9204	287	34	sperm	sperm	NOUN
ct-9204	287	35	where	where	SCONJ
ct-9204	287	36	mir-34c-5p	mir-34c-5p	PROPN
ct-9204	287	37	localizes	localize	VERB
ct-9204	287	38	at	at	ADP
ct-9204	287	39	the	the	DET
ct-9204	287	40	centrosome	centrosome	NOUN
ct-9204	287	41	.	.	PUNCT
ct-9204	288	1	sci	sci	PROPN
ct-9204	288	2	rep	rep	PROPN
ct-9204	288	3	2018;8:16094	2018;8:16094	PROPN
ct-9204	288	4	.	.	PUNCT
ct-9204	289	1	74	74	NUM
ct-9204	289	2	.	.	PUNCT
ct-9204	290	1	hailay	hailay	PROPN
ct-9204	290	2	t	t	PROPN
ct-9204	290	3	,	,	PUNCT
ct-9204	290	4	hoelker	hoelker	PROPN
ct-9204	290	5	m	m	PROPN
ct-9204	290	6	,	,	PUNCT
ct-9204	290	7	poirier	poirier	PROPN
ct-9204	290	8	m	m	PROPN
ct-9204	290	9	,	,	PUNCT
ct-9204	290	10	et	et	PROPN
ct-9204	290	11	al	al	PROPN
ct-9204	290	12	:	:	PUNCT
ct-9204	290	13	extracellular	extracellular	ADJ
ct-9204	290	14	vesicle	vesicle	NOUN
ct-9204	290	15	-	-	PUNCT
ct-9204	290	16	coupled	couple	VERB
ct-9204	290	17	mirna	mirna	NOUN
ct-9204	290	18	profiles	profile	NOUN
ct-9204	290	19	in	in	ADP
ct-9204	290	20	follicular	follicular	ADJ
ct-9204	290	21	fluid	fluid	NOUN
ct-9204	290	22	of	of	ADP
ct-9204	290	23	cows	cow	NOUN
ct-9204	290	24	with	with	ADP
ct-9204	290	25	divergent	divergent	ADJ
ct-9204	290	26	post	post	ADJ
ct-9204	290	27	-	-	ADJ
ct-9204	290	28	calving	calving	ADJ
ct-9204	290	29	metabolic	metabolic	NOUN
ct-9204	290	30	status	status	NOUN
ct-9204	290	31	.	.	PUNCT
ct-9204	291	1	sci	sci	PROPN
ct-9204	291	2	rep	rep	PROPN
ct-9204	291	3	2019;9:1	2019;9:1	PROPN
ct-9204	291	4	-	-	PUNCT
ct-9204	291	5	14	14	NUM
ct-9204	291	6	.	.	PUNCT
ct-9204	291	7	75	75	NUM
ct-9204	291	8	.	.	PUNCT
ct-9204	292	1	lange	lange	NOUN
ct-9204	292	2	-	-	PUNCT
ct-9204	292	3	consiglio	consiglio	PROPN
ct-9204	292	4	a	a	PRON
ct-9204	292	5	,	,	PUNCT
ct-9204	292	6	perrini	perrini	PROPN
ct-9204	292	7	c	c	PROPN
ct-9204	292	8	,	,	PUNCT
ct-9204	292	9	albini	albini	VERB
ct-9204	292	10	g	g	PROPN
ct-9204	292	11	,	,	PUNCT
ct-9204	292	12	et	et	PROPN
ct-9204	292	13	al	al	PROPN
ct-9204	292	14	:	:	PUNCT
ct-9204	292	15	oviductal	oviductal	ADJ
ct-9204	292	16	microvesicles	microvesicle	NOUN
ct-9204	292	17	and	and	CCONJ
ct-9204	292	18	their	their	PRON
ct-9204	292	19	effect	effect	NOUN
ct-9204	292	20	on	on	ADP
ct-9204	292	21	in	in	ADP
ct-9204	292	22	vitro	vitro	X
ct-9204	292	23	maturation	maturation	NOUN
ct-9204	292	24	of	of	ADP
ct-9204	292	25	canine	canine	NOUN
ct-9204	292	26	oocytes	oocyte	NOUN
ct-9204	292	27	.	.	PUNCT
ct-9204	293	1	reproduction	reproduction	NOUN
ct-9204	293	2	2017;154:167	2017;154:167	NUM
ct-9204	293	3	-	-	SYM
ct-9204	293	4	180	180	NUM
ct-9204	293	5	.	.	PUNCT
ct-9204	293	6	76	76	NUM
ct-9204	293	7	.	.	PUNCT
ct-9204	294	1	gündoğan	gündoğan	NOUN
ct-9204	294	2	m	m	PROPN
ct-9204	294	3	:	:	PUNCT
ct-9204	294	4	some	some	DET
ct-9204	294	5	reproductive	reproductive	ADJ
ct-9204	294	6	parameters	parameter	NOUN
ct-9204	294	7	and	and	CCONJ
ct-9204	294	8	seminal	seminal	ADJ
ct-9204	294	9	plasma	plasma	NOUN
ct-9204	294	10	constituents	constituent	NOUN
ct-9204	294	11	in	in	ADP
ct-9204	294	12	relation	relation	NOUN
ct-9204	294	13	to	to	PART
ct-9204	294	14	season	season	NOUN
ct-9204	294	15	in	in	ADP
ct-9204	294	16	akkaraman	akkaraman	NOUN
ct-9204	294	17	and	and	CCONJ
ct-9204	294	18	awassi	awassi	ADJ
ct-9204	294	19	rams	ram	NOUN
ct-9204	294	20	.	.	PUNCT
ct-9204	295	1	turk	turk	PROPN
ct-9204	295	2	j	j	PROPN
ct-9204	295	3	vet	vet	PROPN
ct-9204	295	4	anim	anim	NOUN
ct-9204	295	5	sci	sci	PROPN
ct-9204	295	6	2006;30:95	2006;30:95	NUM
ct-9204	295	7	-	-	PUNCT
ct-9204	295	8	100	100	NUM
ct-9204	295	9	.	.	PUNCT
ct-9204	296	1	77	77	NUM
ct-9204	296	2	.	.	PUNCT
ct-9204	297	1	cardozo	cardozo	PROPN
ct-9204	297	2	j	j	PROPN
ct-9204	297	3	,	,	PUNCT
ct-9204	297	4	fernández	fernández	PROPN
ct-9204	297	5	-	-	PUNCT
ct-9204	297	6	juan	juan	PROPN
ct-9204	297	7	m	m	PROPN
ct-9204	297	8	,	,	PUNCT
ct-9204	297	9	forcada	forcada	PROPN
ct-9204	297	10	f	f	PROPN
ct-9204	297	11	,	,	PUNCT
ct-9204	297	12	et	et	PROPN
ct-9204	297	13	al	al	PROPN
ct-9204	297	14	:	:	PUNCT
ct-9204	297	15	monthly	monthly	ADJ
ct-9204	297	16	variations	variation	NOUN
ct-9204	297	17	in	in	ADP
ct-9204	297	18	ovine	ovine	ADJ
ct-9204	297	19	seminal	seminal	ADJ
ct-9204	297	20	plasma	plasma	NOUN
ct-9204	297	21	proteins	protein	NOUN
ct-9204	297	22	analyzed	analyze	VERB
ct-9204	297	23	by	by	ADP
ct-9204	297	24	twodimensional	twodimensional	ADJ
ct-9204	297	25	polyacrylamide	polyacrylamide	NOUN
ct-9204	297	26	gel	gel	NOUN
ct-9204	297	27	electrophoresis	electrophoresis	NOUN
ct-9204	297	28	.	.	PUNCT
ct-9204	298	1	theriogenology	theriogenology	NOUN
ct-9204	298	2	2006;66:841	2006;66:841	NUM
ct-9204	298	3	-	-	SYM
ct-9204	298	4	850	850	NUM
ct-9204	298	5	.	.	PUNCT
ct-9204	299	1	78	78	NUM
ct-9204	299	2	.	.	PUNCT
ct-9204	300	1	la	la	PROPN
ct-9204	300	2	falci	falci	PROPN
ct-9204	300	3	vsn	vsn	PROPN
ct-9204	300	4	,	,	PUNCT
ct-9204	300	5	tortorella	tortorella	PROPN
ct-9204	300	6	h	h	PROPN
ct-9204	300	7	,	,	PUNCT
ct-9204	300	8	rodrigues	rodrigues	PROPN
ct-9204	300	9	jl	jl	PROPN
ct-9204	300	10	,	,	PUNCT
ct-9204	300	11	et	et	PROPN
ct-9204	300	12	al	al	PROPN
ct-9204	300	13	:	:	PUNCT
ct-9204	300	14	seasonal	seasonal	ADJ
ct-9204	300	15	variation	variation	NOUN
ct-9204	300	16	of	of	ADP
ct-9204	300	17	goat	goat	PROPN
ct-9204	300	18	seminal	seminal	ADJ
ct-9204	300	19	plasma	plasma	NOUN
ct-9204	300	20	proteins	protein	NOUN
ct-9204	300	21	.	.	PUNCT
ct-9204	301	1	theriogenology	theriogenology	NOUN
ct-9204	301	2	2002;57:1035	2002;57:1035	NUM
ct-9204	301	3	-	-	SYM
ct-9204	301	4	1048	1048	NUM
ct-9204	301	5	.	.	PUNCT
ct-9204	302	1	79	79	NUM
ct-9204	302	2	.	.	PUNCT
ct-9204	303	1	aguiar	aguiar	PROPN
ct-9204	303	2	gv	gv	ADP
ct-9204	303	3	,	,	PUNCT
ct-9204	303	4	van	van	PROPN
ct-9204	303	5	tilburg	tilburg	PROPN
ct-9204	303	6	mf	mf	VERB
ct-9204	303	7	,	,	PUNCT
ct-9204	303	8	catunda	catunda	PROPN
ct-9204	303	9	agv	agv	PROPN
ct-9204	303	10	,	,	PUNCT
ct-9204	303	11	et	et	PROPN
ct-9204	303	12	al	al	PROPN
ct-9204	303	13	:	:	PUNCT
ct-9204	303	14	sperm	sperm	NOUN
ct-9204	303	15	parameters	parameter	NOUN
ct-9204	303	16	and	and	CCONJ
ct-9204	303	17	biochemical	biochemical	ADJ
ct-9204	303	18	components	component	NOUN
ct-9204	303	19	of	of	ADP
ct-9204	303	20	goat	goat	PROPN
ct-9204	303	21	seminal	seminal	ADJ
ct-9204	303	22	plasma	plasma	NOUN
ct-9204	303	23	in	in	ADP
ct-9204	303	24	the	the	DET
ct-9204	303	25	rainy	rainy	ADJ
ct-9204	303	26	and	and	CCONJ
ct-9204	303	27	dry	dry	ADJ
ct-9204	303	28	seasons	season	NOUN
ct-9204	303	29	in	in	ADP
ct-9204	303	30	the	the	DET
ct-9204	303	31	brazilian	brazilian	NOUN
ct-9204	303	32	northeast	northeast	NOUN
ct-9204	303	33	:	:	PUNCT
ct-9204	303	34	the	the	DET
ct-9204	303	35	season	season	NOUN
ct-9204	303	36	's	's	PART
ct-9204	303	37	influence	influence	NOUN
ct-9204	303	38	on	on	ADP
ct-9204	303	39	the	the	DET
ct-9204	303	40	cooling	cooling	NOUN
ct-9204	303	41	of	of	ADP
ct-9204	303	42	semen	semen	NOUN
ct-9204	303	43	.	.	PUNCT
ct-9204	304	1	arq	arq	PROPN
ct-9204	304	2	bras	bras	PROPN
ct-9204	304	3	med	med	ADJ
ct-9204	304	4	vet	vet	NOUN
ct-9204	304	5	zootec	zootec	NOUN
ct-9204	304	6	2013;65:6	2013;65:6	NUM
ct-9204	304	7	-	-	SYM
ct-9204	304	8	12	12	NUM
ct-9204	304	9	.	.	PUNCT
ct-9204	304	10	80	80	NUM
ct-9204	304	11	.	.	PUNCT
ct-9204	304	12	domínguez	domínguez	PROPN
ct-9204	304	13	m	m	PROPN
ct-9204	304	14	,	,	PUNCT
ct-9204	304	15	falcinelli	falcinelli	PROPN
ct-9204	304	16	a	a	X
ct-9204	304	17	,	,	PUNCT
ct-9204	304	18	hozbor	hozbor	NOUN
ct-9204	304	19	f	f	X
ct-9204	304	20	,	,	PUNCT
ct-9204	304	21	et	et	PROPN
ct-9204	304	22	al	al	PROPN
ct-9204	304	23	:	:	PUNCT
ct-9204	304	24	seasonal	seasonal	ADJ
ct-9204	304	25	variations	variation	NOUN
ct-9204	304	26	in	in	ADP
ct-9204	304	27	the	the	DET
ct-9204	304	28	composition	composition	NOUN
ct-9204	304	29	of	of	ADP
ct-9204	304	30	ram	ram	NOUN
ct-9204	304	31	seminal	seminal	ADJ
ct-9204	304	32	plasma	plasma	NOUN
ct-9204	304	33	and	and	CCONJ
ct-9204	304	34	its	its	PRON
ct-9204	304	35	effect	effect	NOUN
ct-9204	304	36	on	on	ADP
ct-9204	304	37	frozen	freeze	VERB
ct-9204	304	38	-	-	PUNCT
ct-9204	304	39	thawed	thaw	VERB
ct-9204	304	40	ram	ram	NOUN
ct-9204	304	41	sperm	sperm	NOUN
ct-9204	304	42	.	.	PUNCT
ct-9204	305	1	theriogenology	theriogenology	NOUN
ct-9204	305	2	2008;69:564	2008;69:564	NUM
ct-9204	305	3	-	-	SYM
ct-9204	305	4	573	573	NUM
ct-9204	305	5	.	.	PUNCT
ct-9204	305	6	81	81	NUM
ct-9204	305	7	.	.	PUNCT
ct-9204	306	1	leahy	leahy	PROPN
ct-9204	306	2	t	t	PROPN
ct-9204	306	3	,	,	PUNCT
ct-9204	306	4	rickard	rickard	PROPN
ct-9204	306	5	jp	jp	PROPN
ct-9204	306	6	,	,	PUNCT
ct-9204	306	7	bernecic	bernecic	PROPN
ct-9204	306	8	nc	nc	PROPN
ct-9204	306	9	,	,	PUNCT
ct-9204	306	10	et	et	PROPN
ct-9204	306	11	al	al	PROPN
ct-9204	306	12	:	:	PUNCT
ct-9204	306	13	ram	ram	VERB
ct-9204	306	14	seminal	seminal	ADJ
ct-9204	306	15	plasma	plasma	NOUN
ct-9204	306	16	and	and	CCONJ
ct-9204	306	17	its	its	PRON
ct-9204	306	18	functional	functional	ADJ
ct-9204	306	19	proteomic	proteomic	ADJ
ct-9204	306	20	assessment	assessment	NOUN
ct-9204	306	21	2019;157	2019;157	NUM
ct-9204	306	22	:	:	PUNCT
ct-9204	306	23	r243r256	r243r256	X
ct-9204	306	24	.	.	PUNCT
ct-9204	307	1	82	82	NUM
ct-9204	307	2	.	.	PUNCT
ct-9204	307	3	lange	lange	NOUN
ct-9204	307	4	-	-	PUNCT
ct-9204	307	5	consiglio	consiglio	PROPN
ct-9204	307	6	a	a	PRON
ct-9204	307	7	,	,	PUNCT
ct-9204	307	8	lazzari	lazzari	PROPN
ct-9204	307	9	b	b	PROPN
ct-9204	307	10	,	,	PUNCT
ct-9204	307	11	pizzi	pizzi	PROPN
ct-9204	307	12	f	f	PROPN
ct-9204	307	13	,	,	PUNCT
ct-9204	307	14	et	et	PROPN
ct-9204	307	15	al	al	PROPN
ct-9204	307	16	:	:	PUNCT
ct-9204	307	17	amniotic	amniotic	ADJ
ct-9204	307	18	microvesicles	microvesicle	NOUN
ct-9204	307	19	impact	impact	NOUN
ct-9204	307	20	hatching	hatching	NOUN
ct-9204	307	21	and	and	CCONJ
ct-9204	307	22	pregnancy	pregnancy	NOUN
ct-9204	307	23	percentages	percentage	NOUN
ct-9204	307	24	of	of	ADP
ct-9204	307	25	in	in	ADP
ct-9204	307	26	vitro	vitro	X
ct-9204	307	27	bovine	bovine	ADJ
ct-9204	307	28	embryos	embryo	NOUN
ct-9204	307	29	and	and	CCONJ
ct-9204	307	30	blastocyst	blastocyst	NOUN
ct-9204	307	31	microrna	microrna	PROPN
ct-9204	307	32	expression	expression	NOUN
ct-9204	307	33	versus	versus	ADP
ct-9204	307	34	in	in	ADP
ct-9204	307	35	vi	vi	PROPN
ct-9204	307	36	vo	vo	NOUN
ct-9204	307	37	controls	control	NOUN
ct-9204	307	38	.	.	PUNCT
ct-9204	308	1	sci	sci	PROPN
ct-9204	308	2	rep	rep	PROPN
ct-9204	308	3	2020;10:1	2020;10:1	PROPN
ct-9204	308	4	-	-	SYM
ct-9204	308	5	10	10	NUM
ct-9204	308	6	.	.	PUNCT
ct-9204	308	7	83	83	NUM
ct-9204	308	8	.	.	PUNCT
ct-9204	309	1	lopera	lopera	NOUN
ct-9204	309	2	-	-	PUNCT
ct-9204	309	3	vasquez	vasquez	PROPN
ct-9204	309	4	r	r	PROPN
ct-9204	309	5	,	,	PUNCT
ct-9204	309	6	hamdi	hamdi	PROPN
ct-9204	309	7	m	m	PROPN
ct-9204	309	8	,	,	PUNCT
ct-9204	309	9	maillo	maillo	PROPN
ct-9204	309	10	v	v	PROPN
ct-9204	309	11	,	,	PUNCT
ct-9204	309	12	et	et	PROPN
ct-9204	309	13	al	al	PROPN
ct-9204	309	14	:	:	PUNCT
ct-9204	309	15	effect	effect	NOUN
ct-9204	309	16	of	of	ADP
ct-9204	309	17	bovine	bovine	ADJ
ct-9204	309	18	oviductal	oviductal	ADJ
ct-9204	309	19	extracellular	extracellular	ADJ
ct-9204	309	20	vesicles	vesicle	NOUN
ct-9204	309	21	on	on	ADP
ct-9204	309	22	embryo	embryo	NOUN
ct-9204	309	23	development	development	NOUN
ct-9204	309	24	and	and	CCONJ
ct-9204	309	25	quality	quality	NOUN
ct-9204	309	26	in	in	ADP
ct-9204	309	27	vitro	vitro	X
ct-9204	309	28	.	.	PUNCT
ct-9204	310	1	reproduction	reproduction	NOUN
ct-9204	310	2	2017;153:461	2017;153:461	NUM
ct-9204	310	3	-	-	SYM
ct-9204	310	4	470	470	NUM
ct-9204	310	5	.	.	PUNCT
ct-9204	310	6	84	84	NUM
ct-9204	310	7	.	.	PUNCT
ct-9204	311	1	le	le	X
ct-9204	311	2	bourhis	bourhis	DET
ct-9204	311	3	d	d	X
ct-9204	311	4	,	,	PUNCT
ct-9204	311	5	janati	janati	PROPN
ct-9204	311	6	idrissi	idrissi	PROPN
ct-9204	311	7	s	s	PROPN
ct-9204	311	8	,	,	PUNCT
ct-9204	311	9	mermillod	mermillod	VERB
ct-9204	311	10	p	p	NOUN
ct-9204	311	11	,	,	PUNCT
ct-9204	311	12	et	et	PROPN
ct-9204	311	13	al	al	PROPN
ct-9204	311	14	:	:	PUNCT
ct-9204	311	15	effect	effect	NOUN
ct-9204	311	16	of	of	ADP
ct-9204	311	17	oviductal	oviductal	ADJ
ct-9204	311	18	fluid	fluid	ADJ
ct-9204	311	19	extracellular	extracellular	ADJ
ct-9204	311	20	vesicle	vesicle	NOUN
ct-9204	311	21	supplementation	supplementation	NOUN
ct-9204	311	22	during	during	ADP
ct-9204	311	23	in	in	ADP
ct-9204	311	24	vitro	vitro	X
ct-9204	311	25	culture	culture	NOUN
ct-9204	311	26	on	on	ADP
ct-9204	311	27	development	development	NOUN
ct-9204	311	28	and	and	CCONJ
ct-9204	311	29	quality	quality	NOUN
ct-9204	311	30	of	of	ADP
ct-9204	311	31	bovine	bovine	NOUN
ct-9204	311	32	embryos	embryos	PROPN
ct-9204	311	33	.	.	PUNCT
ct-9204	312	1	reprod	reprod	PROPN
ct-9204	312	2	fertil	fertil	AUX
ct-9204	312	3	dev	dev	VERB
ct-9204	312	4	2020;32:158	2020;32:158	PROPN
ct-9204	312	5	-	-	SYM
ct-9204	312	6	158	158	NUM
ct-9204	312	7	.	.	PUNCT
ct-9204	312	8	85	85	NUM
ct-9204	312	9	.	.	PUNCT
ct-9204	313	1	leal	leal	PROPN
ct-9204	313	2	c	c	PROPN
ct-9204	313	3	,	,	PUNCT
ct-9204	313	4	cañon	cañon	ADJ
ct-9204	313	5	-	-	PUNCT
ct-9204	313	6	beltrán	beltrán	NOUN
ct-9204	313	7	k	k	NOUN
ct-9204	313	8	,	,	PUNCT
ct-9204	313	9	cajas	cajas	PROPN
ct-9204	313	10	y	y	PROPN
ct-9204	313	11	,	,	PUNCT
ct-9204	313	12	et	et	PROPN
ct-9204	313	13	al	al	PROPN
ct-9204	313	14	:	:	PUNCT
ct-9204	313	15	extracellular	extracellular	ADJ
ct-9204	313	16	vesicles	vesicle	NOUN
ct-9204	313	17	from	from	ADP
ct-9204	313	18	oviduct	oviduct	NOUN
ct-9204	313	19	and	and	CCONJ
ct-9204	313	20	uterus	uterus	NOUN
ct-9204	313	21	in	in	ADP
ct-9204	313	22	sequential	sequential	ADJ
ct-9204	313	23	culture	culture	NOUN
ct-9204	313	24	improve	improve	VERB
ct-9204	313	25	the	the	DET
ct-9204	313	26	quality	quality	NOUN
ct-9204	313	27	of	of	ADP
ct-9204	313	28	bovine	bovine	ADJ
ct-9204	313	29	embryos	embryo	NOUN
ct-9204	313	30	produced	produce	VERB
ct-9204	313	31	in	in	ADP
ct-9204	313	32	 	 	SPACE
ct-9204	313	33	vitro	vitro	X
ct-9204	313	34	.	.	PUNCT
ct-9204	314	1	reprod	reprod	PROPN
ct-9204	314	2	fertil	fertil	AUX
ct-9204	314	3	dev	dev	PROPN
ct-9204	314	4	2020;32:164	2020;32:164	PROPN
ct-9204	314	5	-	-	SYM
ct-9204	314	6	164	164	NUM
ct-9204	314	7	.	.	PUNCT
ct-9204	315	1	clinical	clinical	ADJ
ct-9204	315	2	theriogenology	theriogenology	NOUN
ct-9204	315	3	•	•	NOUN
ct-9204	315	4	volume	volume	NOUN
ct-9204	315	5	12	12	NUM
ct-9204	315	6	number	number	NOUN
ct-9204	315	7	2	2	NUM
ct-9204	315	8	•	•	NOUN
ct-9204	315	9	june	june	PROPN
ct-9204	315	10	2020	2020	NUM
ct-9204	315	11	99	99	NUM
ct-9204	315	12	86	86	NUM
ct-9204	315	13	.	.	PUNCT
ct-9204	316	1	park	park	PROPN
ct-9204	316	2	se	se	PROPN
ct-9204	316	3	,	,	PUNCT
ct-9204	316	4	chung	chung	PROPN
ct-9204	316	5	hm	hm	PROPN
ct-9204	316	6	,	,	PUNCT
ct-9204	317	1	cha	cha	PROPN
ct-9204	317	2	ky	ky	PROPN
ct-9204	317	3	,	,	PUNCT
ct-9204	317	4	et	et	PROPN
ct-9204	317	5	al	al	PROPN
ct-9204	317	6	:	:	PUNCT
ct-9204	317	7	cryopreservation	cryopreservation	NOUN
ct-9204	317	8	of	of	ADP
ct-9204	317	9	icr	icr	PROPN
ct-9204	317	10	mouse	mouse	PROPN
ct-9204	317	11	oocytes	oocyte	NOUN
ct-9204	317	12	:	:	PUNCT
ct-9204	317	13	improved	improve	VERB
ct-9204	317	14	post	post	ADJ
ct-9204	317	15	-	-	ADJ
ct-9204	317	16	thawed	thaw	VERB
ct-9204	317	17	preimplantation	preimplantation	NOUN
ct-9204	317	18	development	development	NOUN
ct-9204	317	19	after	after	ADP
ct-9204	317	20	vitrification	vitrification	NOUN
ct-9204	317	21	using	use	VERB
ct-9204	317	22	taxol	taxol	NOUN
ct-9204	317	23	™	™	NOUN
ct-9204	317	24	,	,	PUNCT
ct-9204	317	25	a	a	DET
ct-9204	317	26	cytoskeleton	cytoskeleton	NOUN
ct-9204	317	27	stabilizer	stabilizer	NOUN
ct-9204	317	28	.	.	PUNCT
ct-9204	318	1	fertil	fertil	AUX
ct-9204	318	2	steril	steril	VERB
ct-9204	318	3	2001;75:1177	2001;75:1177	NUM
ct-9204	318	4	-	-	SYM
ct-9204	318	5	1184	1184	NUM
ct-9204	318	6	.	.	PUNCT
ct-9204	319	1	87	87	NUM
ct-9204	319	2	.	.	PUNCT
ct-9204	320	1	morató	morató	PROPN
ct-9204	320	2	r	r	NOUN
ct-9204	320	3	,	,	PUNCT
ct-9204	320	4	izquierdo	izquierdo	PROPN
ct-9204	320	5	d	d	PROPN
ct-9204	320	6	,	,	PUNCT
ct-9204	320	7	albarracín	albarracín	PROPN
ct-9204	320	8	jl	jl	PROPN
ct-9204	320	9	,	,	PUNCT
ct-9204	320	10	et	et	PROPN
ct-9204	320	11	al	al	PROPN
ct-9204	320	12	:	:	PUNCT
ct-9204	320	13	effects	effect	NOUN
ct-9204	320	14	of	of	ADP
ct-9204	320	15	pre‐treating	pre‐treate	VERB
ct-9204	320	16	in	in	ADP
ct-9204	320	17	vitro‐matured	vitro‐mature	VERB
ct-9204	320	18	bovine	bovine	ADJ
ct-9204	320	19	oocytes	oocyte	NOUN
ct-9204	320	20	with	with	ADP
ct-9204	320	21	the	the	DET
ct-9204	320	22	cytoskeleton	cytoskeleton	PROPN
ct-9204	320	23	stabilizing	stabilize	VERB
ct-9204	320	24	agent	agent	NOUN
ct-9204	320	25	taxol	taxol	PROPN
ct-9204	320	26	prior	prior	ADV
ct-9204	320	27	to	to	ADP
ct-9204	320	28	vitrification	vitrification	NOUN
ct-9204	320	29	.	.	PUNCT
ct-9204	321	1	mol	mol	PROPN
ct-9204	321	2	reprod	reprod	PROPN
ct-9204	321	3	dev	dev	PROPN
ct-9204	321	4	2008;75:191	2008;75:191	PROPN
ct-9204	321	5	-	-	NUM
ct-9204	321	6	201	201	NUM
ct-9204	321	7	.	.	PUNCT
ct-9204	322	1	88	88	NUM
ct-9204	322	2	.	.	PUNCT
ct-9204	322	3	pini	pini	PROPN
ct-9204	322	4	t	t	PROPN
ct-9204	322	5	,	,	PUNCT
ct-9204	322	6	rickard	rickard	PROPN
ct-9204	322	7	jp	jp	PROPN
ct-9204	322	8	,	,	PUNCT
ct-9204	322	9	leahy	leahy	PROPN
ct-9204	322	10	t	t	PROPN
ct-9204	322	11	,	,	PUNCT
ct-9204	322	12	et	et	PROPN
ct-9204	322	13	al	al	PROPN
ct-9204	322	14	:	:	PUNCT
ct-9204	322	15	cryopreservation	cryopreservation	NOUN
ct-9204	322	16	and	and	CCONJ
ct-9204	322	17	egg	egg	NOUN
ct-9204	322	18	yolk	yolk	NOUN
ct-9204	322	19	medium	medium	ADJ
ct-9204	322	20	alter	alter	NOUN
ct-9204	322	21	the	the	DET
ct-9204	322	22	proteome	proteome	NOUN
ct-9204	322	23	of	of	ADP
ct-9204	322	24	ram	ram	NOUN
ct-9204	322	25	spermatozoa	spermatozoon	NOUN
ct-9204	322	26	.	.	PUNCT
ct-9204	323	1	proteomics	proteomic	NOUN
ct-9204	323	2	2018;181:73	2018;181:73	NUM
ct-9204	323	3	-	-	SYM
ct-9204	323	4	82	82	NUM
ct-9204	323	5	.	.	NOUN
ct-9204	323	6	89	89	NUM
ct-9204	323	7	.	.	PUNCT
ct-9204	324	1	li	li	PROPN
ct-9204	324	2	p	p	NOUN
ct-9204	324	3	,	,	PUNCT
ct-9204	324	4	hulak	hulak	NOUN
ct-9204	324	5	m	m	PRON
ct-9204	324	6	,	,	PUNCT
ct-9204	324	7	koubek	koubek	PROPN
ct-9204	324	8	p	p	X
ct-9204	324	9	,	,	PUNCT
ct-9204	324	10	et	et	PROPN
ct-9204	324	11	al	al	PROPN
ct-9204	324	12	:	:	PUNCT
ct-9204	324	13	ice	ice	NOUN
ct-9204	324	14	-	-	PUNCT
ct-9204	324	15	age	age	NOUN
ct-9204	324	16	endurance	endurance	NOUN
ct-9204	324	17	:	:	PUNCT
ct-9204	324	18	the	the	DET
ct-9204	324	19	effects	effect	NOUN
ct-9204	324	20	of	of	ADP
ct-9204	324	21	cryopreservation	cryopreservation	NOUN
ct-9204	324	22	on	on	ADP
ct-9204	324	23	proteins	protein	NOUN
ct-9204	324	24	of	of	ADP
ct-9204	324	25	sperm	sperm	NOUN
ct-9204	324	26	of	of	ADP
ct-9204	324	27	common	common	ADJ
ct-9204	324	28	carp	carp	NOUN
ct-9204	324	29	,	,	PUNCT
ct-9204	324	30	cyprinus	cyprinus	ADV
ct-9204	324	31	carpio	carpio	PROPN
ct-9204	324	32	l.	l.	PROPN
ct-9204	324	33	theriogenology	theriogenology	PROPN
ct-9204	324	34	2010;74:413	2010;74:413	PROPN
ct-9204	324	35	-	-	SYM
ct-9204	324	36	423	423	NUM
ct-9204	324	37	.	.	NOUN
ct-9204	324	38	90	90	NUM
ct-9204	324	39	.	.	PUNCT
ct-9204	325	1	mandal	mandal	PROPN
ct-9204	325	2	r	r	PROPN
ct-9204	325	3	,	,	PUNCT
ct-9204	325	4	badyakar	badyakar	PROPN
ct-9204	325	5	d	d	PROPN
ct-9204	325	6	,	,	PUNCT
ct-9204	325	7	chakrabarty	chakrabarty	PROPN
ct-9204	325	8	j	j	PROPN
ct-9204	325	9	:	:	PUNCT
ct-9204	325	10	role	role	NOUN
ct-9204	325	11	of	of	ADP
ct-9204	325	12	membrane	membrane	NOUN
ct-9204	325	13	lipid	lipid	NOUN
ct-9204	325	14	fatty	fatty	NOUN
ct-9204	325	15	acids	acid	NOUN
ct-9204	325	16	in	in	ADP
ct-9204	325	17	sperm	sperm	NOUN
ct-9204	325	18	cryopreservation	cryopreservation	NOUN
ct-9204	325	19	.	.	PUNCT
ct-9204	326	1	advances	advance	NOUN
ct-9204	326	2	in	in	ADP
ct-9204	326	3	andrology	andrology	NOUN
ct-9204	326	4	2014;2014:1	2014;2014:1	NOUN
ct-9204	326	5	-	-	SYM
ct-9204	326	6	9	9	NUM
ct-9204	326	7	.	.	NOUN
ct-9204	326	8	91	91	NUM
ct-9204	326	9	.	.	PUNCT
ct-9204	327	1	chakrabarty	chakrabarty	PROPN
ct-9204	327	2	j	j	PROPN
ct-9204	327	3	,	,	PUNCT
ct-9204	327	4	banerjee	banerjee	PROPN
ct-9204	327	5	d	d	PROPN
ct-9204	327	6	,	,	PUNCT
ct-9204	327	7	pal	pal	NOUN
ct-9204	327	8	d	d	NOUN
ct-9204	327	9	,	,	PUNCT
ct-9204	327	10	et	et	PROPN
ct-9204	327	11	al	al	PROPN
ct-9204	327	12	:	:	PUNCT
ct-9204	327	13	shedding	shed	VERB
ct-9204	327	14	off	off	ADP
ct-9204	327	15	specific	specific	ADJ
ct-9204	327	16	lipid	lipid	NOUN
ct-9204	327	17	constituents	constituent	NOUN
ct-9204	327	18	from	from	ADP
ct-9204	327	19	sperm	sperm	NOUN
ct-9204	327	20	cell	cell	NOUN
ct-9204	327	21	membrane	membrane	NOUN
ct-9204	327	22	during	during	ADP
ct-9204	327	23	cryopreservation	cryopreservation	NOUN
ct-9204	327	24	.	.	PUNCT
ct-9204	328	1	cryobiology	cryobiology	NOUN
ct-9204	328	2	2007;54:27	2007;54:27	NUM
ct-9204	328	3	-	-	SYM
ct-9204	328	4	35	35	NUM
ct-9204	328	5	.	.	PUNCT
ct-9204	328	6	92	92	NUM
ct-9204	328	7	.	.	PUNCT
ct-9204	329	1	fernandez	fernandez	PROPN
ct-9204	329	2	-	-	PUNCT
ct-9204	329	3	trillo	trillo	PROPN
ct-9204	329	4	f	f	PROPN
ct-9204	329	5	,	,	PUNCT
ct-9204	329	6	grover	grover	PROPN
ct-9204	329	7	lm	lm	PROPN
ct-9204	329	8	,	,	PUNCT
ct-9204	329	9	stephenson	stephenson	NOUN
ct-9204	329	10	-	-	PUNCT
ct-9204	329	11	brown	brown	PROPN
ct-9204	329	12	a	a	PROPN
ct-9204	329	13	,	,	PUNCT
ct-9204	329	14	et	et	PROPN
ct-9204	329	15	al	al	PROPN
ct-9204	329	16	:	:	PUNCT
ct-9204	329	17	vesicles	vesicle	NOUN
ct-9204	329	18	in	in	ADP
ct-9204	329	19	nature	nature	NOUN
ct-9204	329	20	and	and	CCONJ
ct-9204	329	21	the	the	DET
ct-9204	329	22	laboratory	laboratory	NOUN
ct-9204	329	23	:	:	PUNCT
ct-9204	329	24	elucidation	elucidation	NOUN
ct-9204	329	25	of	of	ADP
ct-9204	329	26	their	their	PRON
ct-9204	329	27	biological	biological	ADJ
ct-9204	329	28	properties	property	NOUN
ct-9204	329	29	and	and	CCONJ
ct-9204	329	30	synthesis	synthesis	NOUN
ct-9204	329	31	of	of	ADP
ct-9204	329	32	increasingly	increasingly	ADV
ct-9204	329	33	complex	complex	ADJ
ct-9204	329	34	synthetic	synthetic	ADJ
ct-9204	329	35	vesicles	vesicle	NOUN
ct-9204	329	36	.	.	PUNCT
ct-9204	330	1	agnew	agnew	PROPN
ct-9204	330	2	chem	chem	NOUN
ct-9204	330	3	2017;56:3142	2017;56:3142	PROPN
ct-9204	330	4	-	-	SYM
ct-9204	330	5	3160	3160	NUM
ct-9204	330	6	.	.	PUNCT
ct-9204	331	1	93	93	NUM
ct-9204	331	2	.	.	PUNCT
ct-9204	332	1	manjunath	manjunath	PROPN
ct-9204	333	1	p	p	X
ct-9204	333	2	:	:	PUNCT
ct-9204	333	3	new	new	ADJ
ct-9204	333	4	insights	insight	NOUN
ct-9204	333	5	into	into	ADP
ct-9204	333	6	the	the	DET
ct-9204	333	7	understanding	understanding	NOUN
ct-9204	333	8	of	of	ADP
ct-9204	333	9	the	the	DET
ct-9204	333	10	mechanism	mechanism	NOUN
ct-9204	333	11	of	of	ADP
ct-9204	333	12	sperm	sperm	NOUN
ct-9204	333	13	protection	protection	NOUN
ct-9204	333	14	by	by	ADP
ct-9204	333	15	extender	extender	NOUN
ct-9204	333	16	components	component	NOUN
ct-9204	333	17	.	.	PUNCT
ct-9204	334	1	anim	anim	NOUN
ct-9204	334	2	reprod	reprod	PROPN
ct-9204	334	3	2012;9:809	2012;9:809	PROPN
ct-9204	334	4	-	-	PUNCT
ct-9204	334	5	815	815	NUM
ct-9204	334	6	.	.	PUNCT
ct-9204	334	7	94	94	NUM
ct-9204	334	8	.	.	PUNCT
ct-9204	335	1	luna	luna	PROPN
ct-9204	335	2	-	-	PUNCT
ct-9204	335	3	orozco	orozco	PROPN
ct-9204	335	4	jr	jr	PROPN
ct-9204	335	5	,	,	PUNCT
ct-9204	335	6	gonzález	gonzález	PROPN
ct-9204	335	7	-	-	PUNCT
ct-9204	335	8	ramos	ramos	PROPN
ct-9204	335	9	ma	ma	PROPN
ct-9204	335	10	,	,	PUNCT
ct-9204	335	11	calderón	calderón	NOUN
ct-9204	335	12	-	-	PUNCT
ct-9204	335	13	leyva	leyva	NOUN
ct-9204	335	14	g	g	PROPN
ct-9204	335	15	,	,	PUNCT
ct-9204	335	16	et	et	PROPN
ct-9204	335	17	al	al	PROPN
ct-9204	335	18	:	:	PUNCT
ct-9204	335	19	comparison	comparison	NOUN
ct-9204	335	20	of	of	ADP
ct-9204	335	21	different	different	ADJ
ct-9204	335	22	diluents	diluent	NOUN
ct-9204	335	23	based	base	VERB
ct-9204	335	24	on	on	ADP
ct-9204	335	25	liposomes	liposome	NOUN
ct-9204	335	26	and	and	CCONJ
ct-9204	335	27	egg	egg	NOUN
ct-9204	335	28	yolk	yolk	NOUN
ct-9204	335	29	for	for	ADP
ct-9204	335	30	ram	ram	NOUN
ct-9204	335	31	semen	semen	NOUN
ct-9204	335	32	cooling	cooling	NOUN
ct-9204	335	33	and	and	CCONJ
ct-9204	335	34	cryopreservation	cryopreservation	NOUN
ct-9204	335	35	.	.	PUNCT
ct-9204	336	1	iran	iran	PROPN
ct-9204	336	2	j	j	PROPN
ct-9204	336	3	vet	vet	NOUN
ct-9204	336	4	res	re	NOUN
ct-9204	336	5	2019	2019	NUM
ct-9204	336	6	;	;	PUNCT
ct-9204	336	7	20	20	NUM
ct-9204	336	8	:	:	SYM
ct-9204	336	9	126	126	NUM
ct-9204	336	10	-	-	SYM
ct-9204	336	11	130	130	NUM
ct-9204	336	12	.	.	PUNCT
ct-9204	336	13	95	95	NUM
ct-9204	336	14	.	.	PUNCT
ct-9204	337	1	ansari	ansari	PROPN
ct-9204	337	2	ms	ms	PROPN
ct-9204	337	3	,	,	PUNCT
ct-9204	337	4	rakha	rakha	PROPN
ct-9204	337	5	ba	ba	PROPN
ct-9204	337	6	,	,	PUNCT
ct-9204	337	7	akhter	akhter	NOUN
ct-9204	337	8	s	s	PROPN
ct-9204	337	9	,	,	PUNCT
ct-9204	337	10	et	et	PROPN
ct-9204	337	11	al	al	PROPN
ct-9204	337	12	:	:	PUNCT
ct-9204	337	13	optixcell	optixcell	INTJ
ct-9204	337	14	improves	improve	VERB
ct-9204	337	15	the	the	DET
ct-9204	337	16	postthaw	postthaw	NOUN
ct-9204	337	17	quality	quality	NOUN
ct-9204	337	18	and	and	CCONJ
ct-9204	337	19	fertility	fertility	NOUN
ct-9204	337	20	of	of	ADP
ct-9204	337	21	buffalo	buffalo	PROPN
ct-9204	337	22	bull	bull	NOUN
ct-9204	337	23	sperm	sperm	NOUN
ct-9204	337	24	.	.	PUNCT
ct-9204	338	1	theriogenology	theriogenology	NOUN
ct-9204	338	2	2016;85:528	2016;85:528	X
ct-9204	338	3	-	-	SYM
ct-9204	338	4	532	532	NUM
ct-9204	338	5	.	.	NOUN
ct-9204	338	6	96	96	NUM
ct-9204	338	7	.	.	PUNCT
ct-9204	339	1	singh	singh	PROPN
ct-9204	339	2	a	a	PRON
ct-9204	339	3	,	,	PUNCT
ct-9204	339	4	bhakat	bhakat	PROPN
ct-9204	339	5	m	m	PROPN
ct-9204	339	6	,	,	PUNCT
ct-9204	339	7	mohanty	mohanty	PROPN
ct-9204	339	8	tk	tk	PROPN
ct-9204	339	9	,	,	PUNCT
ct-9204	339	10	et	et	PROPN
ct-9204	339	11	al	al	PROPN
ct-9204	339	12	:	:	PUNCT
ct-9204	339	13	effect	effect	NOUN
ct-9204	339	14	of	of	ADP
ct-9204	339	15	tris	tris	ADJ
ct-9204	339	16	-	-	PUNCT
ct-9204	339	17	egg	egg	NOUN
ct-9204	339	18	yolk	yolk	NOUN
ct-9204	339	19	,	,	PUNCT
ct-9204	339	20	soya	soya	NOUN
ct-9204	339	21	milk	milk	NOUN
ct-9204	339	22	,	,	PUNCT
ct-9204	339	23	and	and	CCONJ
ct-9204	339	24	liposome	liposome	NOUN
ct-9204	339	25	-	-	PUNCT
ct-9204	339	26	based	base	VERB
ct-9204	339	27	extenders	extender	NOUN
ct-9204	339	28	on	on	ADP
ct-9204	339	29	sahiwal	sahiwal	PROPN
ct-9204	339	30	(	(	PUNCT
ct-9204	339	31	bos	bos	NOUN
ct-9204	339	32	indicus	indicus	NOUN
ct-9204	339	33	)	)	PUNCT
ct-9204	339	34	sperm	sperm	NOUN
ct-9204	339	35	quality	quality	NOUN
ct-9204	339	36	during	during	ADP
ct-9204	339	37	preand	preand	NOUN
ct-9204	339	38	post	post	ADJ
ct-9204	339	39	-	-	ADJ
ct-9204	339	40	cryopreservation	cryopreservation	NOUN
ct-9204	339	41	stages	stage	NOUN
ct-9204	339	42	.	.	PUNCT
ct-9204	340	1	cryoletters	cryoletter	NOUN
ct-9204	340	2	2019;40:94	2019;40:94	NUM
ct-9204	340	3	-	-	SYM
ct-9204	340	4	102	102	NUM
ct-9204	340	5	.	.	PUNCT
ct-9204	340	6	97	97	NUM
ct-9204	340	7	.	.	PUNCT
ct-9204	341	1	röpke	röpke	PROPN
ct-9204	341	2	t	t	PROPN
ct-9204	341	3	,	,	PUNCT
ct-9204	341	4	oldenhof	oldenhof	NOUN
ct-9204	341	5	h	h	NOUN
ct-9204	341	6	,	,	PUNCT
ct-9204	341	7	leiding	leide	VERB
ct-9204	341	8	c	c	X
ct-9204	341	9	,	,	PUNCT
ct-9204	341	10	et	et	PROPN
ct-9204	341	11	al	al	PROPN
ct-9204	341	12	:	:	PUNCT
ct-9204	341	13	liposomes	liposome	NOUN
ct-9204	341	14	for	for	ADP
ct-9204	341	15	cryopreservation	cryopreservation	NOUN
ct-9204	341	16	of	of	ADP
ct-9204	341	17	bovine	bovine	ADJ
ct-9204	341	18	sperm	sperm	NOUN
ct-9204	341	19	.	.	PUNCT
ct-9204	342	1	theriogenology	theriogenology	NOUN
ct-9204	342	2	2011;76:1465	2011;76:1465	NUM
ct-9204	342	3	-	-	SYM
ct-9204	342	4	1472	1472	NUM
ct-9204	342	5	.	.	PUNCT
ct-9204	343	1	98	98	NUM
ct-9204	343	2	.	.	PUNCT
ct-9204	343	3	stewart	stewart	PROPN
ct-9204	343	4	jl	jl	PROPN
ct-9204	343	5	,	,	PUNCT
ct-9204	343	6	shipley	shipley	PROPN
ct-9204	343	7	cf	cf	PROPN
ct-9204	343	8	,	,	PUNCT
ct-9204	343	9	katich	katich	PROPN
ct-9204	343	10	as	as	ADP
ct-9204	343	11	,	,	PUNCT
ct-9204	343	12	et	et	PROPN
ct-9204	343	13	al	al	PROPN
ct-9204	343	14	:	:	PUNCT
ct-9204	343	15	cryopreservation	cryopreservation	NOUN
ct-9204	343	16	of	of	ADP
ct-9204	343	17	white	white	ADJ
ct-9204	343	18	-	-	PUNCT
ct-9204	343	19	tailed	tail	VERB
ct-9204	343	20	deer	deer	NOUN
ct-9204	343	21	(	(	PUNCT
ct-9204	343	22	odocoileus	odocoileus	ADJ
ct-9204	343	23	virginianus	virginianus	NOUN
ct-9204	343	24	)	)	PUNCT
ct-9204	343	25	semen	seman	NOUN
ct-9204	343	26	using	use	VERB
ct-9204	343	27	soybean-	soybean-	NOUN
ct-9204	343	28	,	,	PUNCT
ct-9204	343	29	liposome-	liposome-	NOUN
ct-9204	343	30	,	,	PUNCT
ct-9204	343	31	and	and	CCONJ
ct-9204	343	32	egg	egg	NOUN
ct-9204	343	33	yolk	yolk	NOUN
ct-9204	343	34	-	-	PUNCT
ct-9204	343	35	based	base	VERB
ct-9204	343	36	extenders	extender	NOUN
ct-9204	343	37	.	.	PUNCT
ct-9204	344	1	anim	anim	NOUN
ct-9204	344	2	reprod	reprod	PROPN
ct-9204	344	3	sci	sci	PROPN
ct-9204	344	4	2016;171:7	2016;171:7	PROPN
ct-9204	344	5	-	-	SYM
ct-9204	344	6	16	16	NUM
ct-9204	344	7	.	.	PUNCT
ct-9204	344	8	99	99	NUM
ct-9204	344	9	.	.	PUNCT
ct-9204	345	1	wojtusik	wojtusik	PROPN
ct-9204	345	2	j	j	PROPN
ct-9204	345	3	,	,	PUNCT
ct-9204	345	4	stoops	stoop	VERB
ct-9204	345	5	ma	ma	PROPN
ct-9204	345	6	,	,	PUNCT
ct-9204	345	7	roth	roth	PROPN
ct-9204	345	8	tl	tl	PROPN
ct-9204	345	9	:	:	PUNCT
ct-9204	345	10	animal	animal	NOUN
ct-9204	345	11	protein	protein	NOUN
ct-9204	345	12	-	-	PUNCT
ct-9204	345	13	free	free	ADJ
ct-9204	345	14	optixcell	optixcell	NOUN
ct-9204	345	15	and	and	CCONJ
ct-9204	345	16	shortened	shorten	VERB
ct-9204	345	17	equilibration	equilibration	NOUN
ct-9204	345	18	periods	period	NOUN
ct-9204	345	19	can	can	AUX
ct-9204	345	20	replace	replace	VERB
ct-9204	345	21	egg	egg	NOUN
ct-9204	345	22	yolk	yolk	NOUN
ct-9204	345	23	-	-	PUNCT
ct-9204	345	24	based	base	VERB
ct-9204	345	25	extender	extender	NOUN
ct-9204	345	26	and	and	CCONJ
ct-9204	345	27	slow	slow	ADJ
ct-9204	345	28	cooling	cooling	NOUN
ct-9204	345	29	for	for	ADP
ct-9204	345	30	rhinoceros	rhinoceros	NOUN
ct-9204	345	31	semen	semen	NOUN
ct-9204	345	32	cryopreservation	cryopreservation	NOUN
ct-9204	345	33	.	.	PUNCT
ct-9204	346	1	cryobiology	cryobiology	NOUN
ct-9204	346	2	2019;89:21	2019;89:21	NUM
ct-9204	346	3	-	-	SYM
ct-9204	346	4	25	25	NUM
ct-9204	346	5	.	.	NOUN
ct-9204	346	6	100	100	NUM
ct-9204	346	7	.	.	PUNCT
ct-9204	347	1	li	li	PROPN
ct-9204	347	2	j	j	PROPN
ct-9204	347	3	,	,	PUNCT
ct-9204	347	4	lee	lee	PROPN
ct-9204	347	5	y	y	PROPN
ct-9204	347	6	,	,	PUNCT
ct-9204	347	7	johansson	johansson	PROPN
ct-9204	347	8	hj	hj	PROPN
ct-9204	347	9	,	,	PUNCT
ct-9204	347	10	et	et	PROPN
ct-9204	347	11	al	al	PROPN
ct-9204	347	12	:	:	PUNCT
ct-9204	347	13	serum	serum	NOUN
ct-9204	347	14	-	-	PUNCT
ct-9204	347	15	free	free	ADJ
ct-9204	347	16	culture	culture	NOUN
ct-9204	347	17	alters	alter	VERB
ct-9204	347	18	the	the	DET
ct-9204	347	19	quantity	quantity	NOUN
ct-9204	347	20	and	and	CCONJ
ct-9204	347	21	protein	protein	NOUN
ct-9204	347	22	composition	composition	NOUN
ct-9204	347	23	of	of	ADP
ct-9204	347	24	neuroblastomaderived	neuroblastomaderived	ADJ
ct-9204	347	25	extracellular	extracellular	ADJ
ct-9204	347	26	vesicles	vesicle	NOUN
ct-9204	347	27	.	.	PUNCT
ct-9204	348	1	j	j	PROPN
ct-9204	348	2	extracell	extracell	PROPN
ct-9204	348	3	vesicles	vesicle	NOUN
ct-9204	348	4	2015;4:26883	2015;4:26883	NUM
ct-9204	348	5	.	.	PUNCT
ct-9204	349	1	101	101	NUM
ct-9204	349	2	.	.	PUNCT
ct-9204	350	1	brzozowski	brzozowski	PROPN
ct-9204	350	2	js	js	PROPN
ct-9204	350	3	,	,	PUNCT
ct-9204	350	4	jankowski	jankowski	PROPN
ct-9204	350	5	h	h	PROPN
ct-9204	350	6	,	,	PUNCT
ct-9204	350	7	bond	bond	PROPN
ct-9204	350	8	dr	dr	PROPN
ct-9204	350	9	,	,	PUNCT
ct-9204	350	10	et	et	PROPN
ct-9204	350	11	al	al	PROPN
ct-9204	350	12	:	:	PUNCT
ct-9204	350	13	lipidomic	lipidomic	ADJ
ct-9204	350	14	profiling	profiling	NOUN
ct-9204	350	15	of	of	ADP
ct-9204	350	16	extracellular	extracellular	ADJ
ct-9204	350	17	vesicles	vesicle	NOUN
ct-9204	350	18	derived	derive	VERB
ct-9204	350	19	from	from	ADP
ct-9204	350	20	prostate	prostate	NOUN
ct-9204	350	21	and	and	CCONJ
ct-9204	350	22	prostate	prostate	NOUN
ct-9204	350	23	cancer	cancer	NOUN
ct-9204	350	24	cell	cell	NOUN
ct-9204	350	25	lines	line	NOUN
ct-9204	350	26	.	.	PUNCT
ct-9204	351	1	lipids	lipids	ADP
ct-9204	351	2	in	in	ADP
ct-9204	351	3	health	health	NOUN
ct-9204	351	4	and	and	CCONJ
ct-9204	351	5	disease	disease	NOUN
ct-9204	351	6	2018;17:211	2018;17:211	NUM
ct-9204	351	7	.	.	PUNCT
ct-9204	352	1	102	102	NUM
ct-9204	352	2	.	.	PUNCT
ct-9204	353	1	davies	davy	NOUN
ct-9204	353	2	og	og	PROPN
ct-9204	353	3	,	,	PUNCT
ct-9204	353	4	rafiq	rafiq	PROPN
ct-9204	353	5	qa	qa	PROPN
ct-9204	353	6	:	:	PUNCT
ct-9204	353	7	considerations	consideration	NOUN
ct-9204	353	8	for	for	ADP
ct-9204	353	9	the	the	DET
ct-9204	353	10	bioprocessing	bioprocessing	NOUN
ct-9204	353	11	,	,	PUNCT
ct-9204	353	12	manufacture	manufacture	NOUN
ct-9204	353	13	and	and	CCONJ
ct-9204	353	14	translation	translation	NOUN
ct-9204	353	15	of	of	ADP
ct-9204	353	16	extracellular	extracellular	ADJ
ct-9204	353	17	vesicles	vesicle	NOUN
ct-9204	353	18	for	for	ADP
ct-9204	353	19	therapeutic	therapeutic	ADJ
ct-9204	353	20	and	and	CCONJ
ct-9204	353	21	diagnostic	diagnostic	ADJ
ct-9204	353	22	applications	application	NOUN
ct-9204	353	23	.	.	PUNCT
ct-9204	354	1	cell	cell	NOUN
ct-9204	354	2	gene	gene	NOUN
ct-9204	354	3	ther	ther	ADV
ct-9204	354	4	insights	insight	VERB
ct-9204	354	5	2017;3:683	2017;3:683	NUM
ct-9204	354	6	-	-	SYM
ct-9204	354	7	694	694	NUM
ct-9204	354	8	.	.	PUNCT
ct-9204	354	9	103	103	NUM
ct-9204	354	10	.	.	PUNCT
ct-9204	355	1	palviainen	palviainen	PROPN
ct-9204	355	2	m	m	PROPN
ct-9204	355	3	,	,	PUNCT
ct-9204	355	4	saari	saari	PROPN
ct-9204	355	5	h	h	NOUN
ct-9204	355	6	,	,	PUNCT
ct-9204	355	7	kärkkäinen	kärkkäinen	PROPN
ct-9204	355	8	o	o	NOUN
ct-9204	355	9	,	,	PUNCT
ct-9204	355	10	et	et	PROPN
ct-9204	355	11	al	al	PROPN
ct-9204	355	12	:	:	PUNCT
ct-9204	355	13	metabolic	metabolic	ADJ
ct-9204	355	14	signature	signature	NOUN
ct-9204	355	15	of	of	ADP
ct-9204	355	16	extracellular	extracellular	ADJ
ct-9204	355	17	vesicles	vesicle	NOUN
ct-9204	355	18	depends	depend	VERB
ct-9204	355	19	on	on	ADP
ct-9204	355	20	the	the	DET
ct-9204	355	21	cell	cell	NOUN
ct-9204	355	22	culture	culture	NOUN
ct-9204	355	23	conditions	condition	NOUN
ct-9204	355	24	.	.	PUNCT
ct-9204	356	1	journal	journal	NOUN
ct-9204	356	2	of	of	ADP
ct-9204	356	3	extracellular	extracellular	ADJ
ct-9204	356	4	vesicles	vesicle	NOUN
ct-9204	356	5	2019;8:1596669	2019;8:1596669	NOUN
ct-9204	356	6	.	.	PUNCT
ct-9204	357	1	104	104	NUM
ct-9204	357	2	.	.	PUNCT
ct-9204	358	1	patel	patel	PROPN
ct-9204	358	2	db	db	PROPN
ct-9204	358	3	,	,	PUNCT
ct-9204	358	4	santoro	santoro	PROPN
ct-9204	358	5	m	m	PRON
ct-9204	358	6	,	,	PUNCT
ct-9204	358	7	born	bear	VERB
ct-9204	358	8	lj	lj	PROPN
ct-9204	358	9	,	,	PUNCT
ct-9204	358	10	et	et	PROPN
ct-9204	358	11	al	al	PROPN
ct-9204	358	12	:	:	PUNCT
ct-9204	358	13	towards	towards	ADP
ct-9204	358	14	rationally	rationally	ADV
ct-9204	358	15	designed	design	VERB
ct-9204	358	16	biomanufacturing	biomanufacturing	NOUN
ct-9204	358	17	of	of	ADP
ct-9204	358	18	therapeutic	therapeutic	ADJ
ct-9204	358	19	extracellular	extracellular	ADJ
ct-9204	358	20	vesicles	vesicle	NOUN
ct-9204	358	21	:	:	PUNCT
ct-9204	358	22	impact	impact	NOUN
ct-9204	358	23	of	of	ADP
ct-9204	358	24	the	the	DET
ct-9204	358	25	bioproduction	bioproduction	NOUN
ct-9204	358	26	microenvironment	microenvironment	NOUN
ct-9204	358	27	.	.	PUNCT
ct-9204	359	1	biotechnol	biotechnol	PROPN
ct-9204	359	2	adv	adv	PROPN
ct-9204	359	3	2018;36:2051	2018;36:2051	NUM
ct-9204	359	4	-	-	PUNCT
ct-9204	359	5	2059	2059	NUM
ct-9204	359	6	.	.	PUNCT
ct-9204	360	1	105	105	NUM
ct-9204	360	2	.	.	PUNCT
ct-9204	361	1	kuravi	kuravi	PROPN
ct-9204	361	2	sj	sj	PROPN
ct-9204	361	3	,	,	PUNCT
ct-9204	361	4	yates	yates	PROPN
ct-9204	361	5	cm	cm	PROPN
ct-9204	361	6	,	,	PUNCT
ct-9204	361	7	foster	foster	PROPN
ct-9204	361	8	m	m	PROPN
ct-9204	361	9	,	,	PUNCT
ct-9204	361	10	et	et	PROPN
ct-9204	361	11	al	al	PROPN
ct-9204	361	12	:	:	PUNCT
ct-9204	361	13	changes	change	NOUN
ct-9204	361	14	in	in	ADP
ct-9204	361	15	the	the	DET
ct-9204	361	16	pattern	pattern	NOUN
ct-9204	361	17	of	of	ADP
ct-9204	361	18	plasma	plasma	NOUN
ct-9204	361	19	extracellular	extracellular	ADJ
ct-9204	361	20	vesicles	vesicle	NOUN
ct-9204	361	21	after	after	ADP
ct-9204	361	22	severe	severe	ADJ
ct-9204	361	23	trauma	trauma	NOUN
ct-9204	361	24	.	.	PUNCT
ct-9204	362	1	plos	plos	PROPN
ct-9204	362	2	one	one	NUM
ct-9204	362	3	2017;12	2017;12	NOUN
ct-9204	362	4	:	:	PUNCT
ct-9204	362	5	e0183640	e0183640	ADJ
ct-9204	362	6	.	.	NOUN
ct-9204	363	1	106	106	NUM
ct-9204	363	2	.	.	PUNCT
ct-9204	363	3	de	de	PROPN
ct-9204	363	4	jong	jong	PROPN
ct-9204	363	5	og	og	PROPN
ct-9204	363	6	,	,	PUNCT
ct-9204	363	7	verhaar	verhaar	PROPN
ct-9204	363	8	mc	mc	PROPN
ct-9204	363	9	,	,	PUNCT
ct-9204	363	10	chen	chen	PROPN
ct-9204	363	11	y	y	PROPN
ct-9204	363	12	,	,	PUNCT
ct-9204	363	13	et	et	PROPN
ct-9204	363	14	al	al	PROPN
ct-9204	363	15	:	:	PUNCT
ct-9204	363	16	cellular	cellular	ADJ
ct-9204	363	17	stress	stress	NOUN
ct-9204	363	18	conditions	condition	NOUN
ct-9204	363	19	are	be	AUX
ct-9204	363	20	reflected	reflect	VERB
ct-9204	363	21	in	in	ADP
ct-9204	363	22	the	the	DET
ct-9204	363	23	protein	protein	NOUN
ct-9204	363	24	and	and	CCONJ
ct-9204	363	25	rna	rna	NOUN
ct-9204	363	26	content	content	NOUN
ct-9204	363	27	of	of	ADP
ct-9204	363	28	endothelial	endothelial	ADJ
ct-9204	363	29	cell	cell	NOUN
ct-9204	363	30	-	-	PUNCT
ct-9204	363	31	derived	derive	VERB
ct-9204	363	32	exosomes	exosome	NOUN
ct-9204	363	33	.	.	PUNCT
ct-9204	364	1	j	j	PROPN
ct-9204	364	2	extracell	extracell	PROPN
ct-9204	364	3	vesicles	vesicle	NOUN
ct-9204	364	4	2012;1:18396	2012;1:18396	NUM
ct-9204	364	5	.	.	PUNCT
ct-9204	365	1	107	107	NUM
ct-9204	365	2	.	.	PUNCT
ct-9204	366	1	apodaca	apodaca	PROPN
ct-9204	366	2	g	g	NOUN
ct-9204	366	3	:	:	PUNCT
ct-9204	366	4	modulation	modulation	NOUN
ct-9204	366	5	of	of	ADP
ct-9204	366	6	membrane	membrane	NOUN
ct-9204	366	7	traffic	traffic	NOUN
ct-9204	366	8	by	by	ADP
ct-9204	366	9	mechanical	mechanical	ADJ
ct-9204	366	10	stimuli	stimulus	NOUN
ct-9204	366	11	.	.	PUNCT
ct-9204	367	1	am	be	AUX
ct-9204	367	2	j	j	PROPN
ct-9204	367	3	physiol	physiol	PROPN
ct-9204	367	4	-	-	PUNCT
ct-9204	367	5	renal	renal	ADJ
ct-9204	367	6	2002;282	2002;282	NUM
ct-9204	367	7	:	:	PUNCT
ct-9204	367	8	f179	f179	PROPN
ct-9204	367	9	-	-	PUNCT
ct-9204	367	10	f190	f190	PROPN
ct-9204	367	11	.	.	PROPN
ct-9204	367	12	108	108	NUM
ct-9204	367	13	.	.	PUNCT
ct-9204	368	1	ferraz	ferraz	PROPN
ct-9204	368	2	ma	ma	PROPN
ct-9204	368	3	,	,	PUNCT
ct-9204	368	4	henning	henning	PROPN
ct-9204	368	5	hh	hh	PROPN
ct-9204	368	6	,	,	PUNCT
ct-9204	368	7	costa	costa	PROPN
ct-9204	368	8	pf	pf	PROPN
ct-9204	368	9	,	,	PUNCT
ct-9204	368	10	et	et	PROPN
ct-9204	368	11	al	al	PROPN
ct-9204	368	12	:	:	PUNCT
ct-9204	368	13	improved	improve	VERB
ct-9204	368	14	bovine	bovine	ADJ
ct-9204	368	15	embryo	embryo	NOUN
ct-9204	368	16	production	production	NOUN
ct-9204	368	17	in	in	ADP
ct-9204	368	18	an	an	DET
ct-9204	368	19	oviduct	oviduct	NOUN
ct-9204	368	20	-	-	PUNCT
ct-9204	368	21	on	on	ADP
ct-9204	368	22	-	-	PUNCT
ct-9204	368	23	a	a	DET
ct-9204	368	24	-	-	PUNCT
ct-9204	368	25	chip	chip	NOUN
ct-9204	368	26	system	system	NOUN
ct-9204	368	27	:	:	PUNCT
ct-9204	368	28	prevention	prevention	NOUN
ct-9204	368	29	of	of	ADP
ct-9204	368	30	poly	poly	ADJ
ct-9204	368	31	-	-	PUNCT
ct-9204	368	32	spermic	spermic	ADJ
ct-9204	368	33	fertilization	fertilization	NOUN
ct-9204	368	34	and	and	CCONJ
ct-9204	368	35	parthenogenic	parthenogenic	ADJ
ct-9204	368	36	activation	activation	NOUN
ct-9204	368	37	.	.	PUNCT
ct-9204	369	1	lab	lab	NOUN
ct-9204	369	2	chip	chip	NOUN
ct-9204	369	3	201717:905	201717:905	VERB
ct-9204	369	4	-	-	PUNCT
ct-9204	369	5	916	916	NUM
ct-9204	369	6	.	.	PUNCT
ct-9204	370	1	109	109	NUM
ct-9204	370	2	.	.	PUNCT
ct-9204	371	1	li	li	PROPN
ct-9204	371	2	w	w	PROPN
ct-9204	371	3	-	-	PUNCT
ct-9204	371	4	x	x	PROPN
ct-9204	371	5	,	,	PUNCT
ct-9204	371	6	liang	liang	PROPN
ct-9204	371	7	g	g	PROPN
ct-9204	371	8	-	-	PUNCT
ct-9204	371	9	t	t	PROPN
ct-9204	371	10	,	,	PUNCT
ct-9204	371	11	yan	yan	PROPN
ct-9204	372	1	w	w	PROPN
ct-9204	372	2	,	,	PUNCT
ct-9204	372	3	et	et	PROPN
ct-9204	372	4	al	al	PROPN
ct-9204	372	5	:	:	PUNCT
ct-9204	372	6	artificial	artificial	ADJ
ct-9204	372	7	uterus	uterus	NOUN
ct-9204	372	8	on	on	ADP
ct-9204	372	9	a	a	DET
ct-9204	372	10	microfluidic	microfluidic	ADJ
ct-9204	372	11	chip	chip	NOUN
ct-9204	372	12	.	.	PUNCT
ct-9204	373	1	chinese	chinese	PROPN
ct-9204	373	2	j	j	PROPN
ct-9204	373	3	anal	anal	ADJ
ct-9204	373	4	chem	chem	NOUN
ct-9204	373	5	2013	2013	NUM
ct-9204	373	6	41:467	41:467	NUM
ct-9204	373	7	-	-	NOUN
ct-9204	373	8	472	472	NUM
ct-9204	373	9	.	.	PUNCT
ct-9204	374	1	110	110	NUM
ct-9204	374	2	.	.	PUNCT
ct-9204	375	1	hjelm	hjelm	PROPN
ct-9204	375	2	be	be	AUX
ct-9204	375	3	,	,	PUNCT
ct-9204	375	4	berta	berta	PROPN
ct-9204	375	5	an	an	PROPN
ct-9204	375	6	,	,	PUNCT
ct-9204	375	7	nickerson	nickerson	PROPN
ct-9204	375	8	ca	can	AUX
ct-9204	375	9	,	,	PUNCT
ct-9204	375	10	et	et	PROPN
ct-9204	375	11	al	al	PROPN
ct-9204	375	12	:	:	PUNCT
ct-9204	375	13	development	development	NOUN
ct-9204	375	14	and	and	CCONJ
ct-9204	375	15	characterization	characterization	NOUN
ct-9204	375	16	of	of	ADP
ct-9204	375	17	a	a	DET
ct-9204	375	18	three	three	NUM
ct-9204	375	19	-	-	PUNCT
ct-9204	375	20	dimensional	dimensional	ADJ
ct-9204	375	21	organotypic	organotypic	ADJ
ct-9204	375	22	human	human	ADJ
ct-9204	375	23	vaginal	vaginal	ADJ
ct-9204	375	24	epithelial	epithelial	ADJ
ct-9204	375	25	cell	cell	NOUN
ct-9204	375	26	model	model	NOUN
ct-9204	375	27	.	.	PUNCT
ct-9204	376	1	biol	biol	PROPN
ct-9204	376	2	reprod	reprod	PROPN
ct-9204	376	3	2010;82:617	2010;82:617	PROPN
ct-9204	376	4	-	-	SYM
ct-9204	376	5	627	627	NUM
ct-9204	376	6	.	.	NOUN
ct-9204	376	7	111	111	NUM
ct-9204	376	8	.	.	PUNCT
ct-9204	377	1	xiao	xiao	PROPN
ct-9204	377	2	s	s	PROPN
ct-9204	377	3	,	,	PUNCT
ct-9204	377	4	coppeta	coppeta	PROPN
ct-9204	377	5	jr	jr	PROPN
ct-9204	377	6	,	,	PUNCT
ct-9204	377	7	rogers	rogers	PROPN
ct-9204	377	8	hb	hb	PROPN
ct-9204	377	9	,	,	PUNCT
ct-9204	377	10	et	et	PROPN
ct-9204	377	11	al	al	PROPN
ct-9204	377	12	:	:	PUNCT
ct-9204	377	13	a	a	DET
ct-9204	377	14	microfluidic	microfluidic	ADJ
ct-9204	377	15	culture	culture	NOUN
ct-9204	377	16	model	model	NOUN
ct-9204	377	17	of	of	ADP
ct-9204	377	18	the	the	DET
ct-9204	377	19	human	human	ADJ
ct-9204	377	20	reproductive	reproductive	ADJ
ct-9204	377	21	tract	tract	NOUN
ct-9204	377	22	and	and	CCONJ
ct-9204	377	23	28	28	NUM
ct-9204	377	24	-	-	PUNCT
ct-9204	377	25	day	day	NOUN
ct-9204	377	26	menstrual	menstrual	ADJ
ct-9204	377	27	cycle	cycle	NOUN
ct-9204	377	28	.	.	PUNCT
ct-9204	378	1	nat	nat	PROPN
ct-9204	378	2	commun	commun	PROPN
ct-9204	378	3	2017;8:14584	2017;8:14584	PROPN
ct-9204	378	4	-	-	PROPN
ct-9204	378	5	14584	14584	NUM
ct-9204	378	6	.	.	PUNCT
ct-9204	379	1	112	112	NUM
ct-9204	379	2	.	.	PUNCT
ct-9204	380	1	nagashima	nagashima	PROPN
ct-9204	380	2	jb	jb	PROPN
ct-9204	380	3	,	,	PUNCT
ct-9204	380	4	el	el	PROPN
ct-9204	380	5	assal	assal	PROPN
ct-9204	380	6	r	r	PROPN
ct-9204	380	7	,	,	PUNCT
ct-9204	380	8	songsasen	songsasen	NOUN
ct-9204	380	9	n	n	CCONJ
ct-9204	380	10	,	,	PUNCT
ct-9204	380	11	et	et	PROPN
ct-9204	380	12	al	al	PROPN
ct-9204	380	13	:	:	PUNCT
ct-9204	380	14	evaluation	evaluation	NOUN
ct-9204	380	15	of	of	ADP
ct-9204	380	16	an	an	DET
ct-9204	380	17	ovary‐on‐a‐chip	ovary‐on‐a‐chip	NOUN
ct-9204	380	18	in	in	ADP
ct-9204	380	19	large	large	ADJ
ct-9204	380	20	mammalian	mammalian	ADJ
ct-9204	380	21	models	model	NOUN
ct-9204	380	22	:	:	PUNCT
ct-9204	380	23	species	specie	NOUN
ct-9204	380	24	specificity	specificity	NOUN
ct-9204	380	25	and	and	CCONJ
ct-9204	380	26	influence	influence	NOUN
ct-9204	380	27	of	of	ADP
ct-9204	380	28	follicle	follicle	NOUN
ct-9204	380	29	isolation	isolation	NOUN
ct-9204	380	30	status	status	NOUN
ct-9204	380	31	.	.	PUNCT
ct-9204	381	1	j	j	PROPN
ct-9204	381	2	tissue	tissue	NOUN
ct-9204	381	3	eng	eng	PROPN
ct-9204	381	4	regen	regen	PROPN
ct-9204	381	5	m	m	PROPN
ct-9204	381	6	2018;12	2018;12	NUM
ct-9204	381	7	:	:	PUNCT
ct-9204	381	8	e1926	e1926	NOUN
ct-9204	381	9	-	-	PUNCT
ct-9204	381	10	e1935	e1935	PROPN
ct-9204	381	11	.	.	PUNCT
ct-9204	382	1	113	113	NUM
ct-9204	382	2	.	.	PUNCT
ct-9204	383	1	komeya	komeya	PROPN
ct-9204	383	2	m	m	PROPN
ct-9204	383	3	,	,	PUNCT
ct-9204	383	4	hayashi	hayashi	PROPN
ct-9204	383	5	k	k	PROPN
ct-9204	383	6	,	,	PUNCT
ct-9204	383	7	nakamura	nakamura	PROPN
ct-9204	383	8	h	h	PROPN
ct-9204	383	9	,	,	PUNCT
ct-9204	383	10	et	et	PROPN
ct-9204	383	11	al	al	PROPN
ct-9204	383	12	:	:	PUNCT
ct-9204	383	13	pumpless	pumpless	ADJ
ct-9204	383	14	microfluidic	microfluidic	ADJ
ct-9204	383	15	system	system	NOUN
ct-9204	383	16	driven	drive	VERB
ct-9204	383	17	by	by	ADP
ct-9204	383	18	hydrostatic	hydrostatic	ADJ
ct-9204	383	19	pressure	pressure	NOUN
ct-9204	383	20	induces	induce	NOUN
ct-9204	383	21	and	and	CCONJ
ct-9204	383	22	maintains	maintain	VERB
ct-9204	383	23	mouse	mouse	NOUN
ct-9204	383	24	spermatogenesis	spermatogenesis	NOUN
ct-9204	383	25	in	in	ADP
ct-9204	383	26	vitro	vitro	X
ct-9204	383	27	.	.	PUNCT
ct-9204	384	1	sci	sci	PROPN
ct-9204	384	2	rep	rep	PROPN
ct-9204	384	3	2017;7:1	2017;7:1	PROPN
ct-9204	384	4	-	-	PUNCT
ct-9204	384	5	8	8	NUM
ct-9204	384	6	.	.	X
ct-9204	384	7	114	114	NUM
ct-9204	384	8	.	.	PUNCT
ct-9204	385	1	komeya	komeya	PROPN
ct-9204	385	2	m	m	PRON
ct-9204	385	3	,	,	PUNCT
ct-9204	385	4	kimura	kimura	NOUN
ct-9204	385	5	h	h	NOUN
ct-9204	385	6	,	,	PUNCT
ct-9204	385	7	nakamura	nakamura	PROPN
ct-9204	385	8	h	h	PROPN
ct-9204	385	9	,	,	PUNCT
ct-9204	385	10	et	et	PROPN
ct-9204	385	11	al	al	PROPN
ct-9204	385	12	:	:	PUNCT
ct-9204	385	13	long	long	ADJ
ct-9204	385	14	-	-	PUNCT
ct-9204	385	15	term	term	NOUN
ct-9204	385	16	ex	ex	PRON
ct-9204	385	17	vivo	vivo	NOUN
ct-9204	385	18	maintenance	maintenance	NOUN
ct-9204	385	19	of	of	ADP
ct-9204	385	20	testis	testis	NOUN
ct-9204	385	21	tissues	tissue	NOUN
ct-9204	385	22	producing	produce	VERB
ct-9204	385	23	fertile	fertile	ADJ
ct-9204	385	24	sperm	sperm	NOUN
ct-9204	385	25	in	in	ADP
ct-9204	385	26	a	a	DET
ct-9204	385	27	microfluidic	microfluidic	ADJ
ct-9204	385	28	device	device	NOUN
ct-9204	385	29	.	.	PUNCT
ct-9204	386	1	sci	sci	PROPN
ct-9204	386	2	rep	rep	PROPN
ct-9204	386	3	2016;6:1	2016;6:1	NUM
ct-9204	386	4	-	-	SYM
ct-9204	386	5	10	10	NUM
ct-9204	386	6	.	.	PUNCT
ct-9204	386	7	115	115	NUM
ct-9204	386	8	.	.	PUNCT
ct-9204	387	1	yamanaka	yamanaka	PROPN
ct-9204	387	2	h	h	PROPN
ct-9204	387	3	,	,	PUNCT
ct-9204	387	4	komeya	komeya	PROPN
ct-9204	387	5	m	m	PROPN
ct-9204	387	6	,	,	PUNCT
ct-9204	387	7	nakamura	nakamura	PROPN
ct-9204	387	8	h	h	PROPN
ct-9204	387	9	,	,	PUNCT
ct-9204	387	10	et	et	PROPN
ct-9204	387	11	al	al	PROPN
ct-9204	387	12	:	:	PUNCT
ct-9204	387	13	a	a	DET
ct-9204	387	14	monolayer	monolayer	NOUN
ct-9204	387	15	microfluidic	microfluidic	ADJ
ct-9204	387	16	device	device	NOUN
ct-9204	387	17	supporting	support	VERB
ct-9204	387	18	mouse	mouse	NOUN
ct-9204	387	19	spermatogenesis	spermatogenesis	NOUN
ct-9204	387	20	with	with	ADP
ct-9204	387	21	improved	improved	ADJ
ct-9204	387	22	visibility	visibility	NOUN
ct-9204	387	23	.	.	PUNCT
ct-9204	388	1	biochem	biochem	PROPN
ct-9204	388	2	biophys	biophys	PROPN
ct-9204	388	3	res	re	NOUN
ct-9204	388	4	commun	commun	PROPN
ct-9204	388	5	2018;500:885	2018;500:885	NOUN
ct-9204	388	6	-	-	SYM
ct-9204	388	7	891	891	NUM
ct-9204	388	8	.	.	PUNCT
ct-9204	389	1	116	116	NUM
ct-9204	389	2	.	.	PUNCT
ct-9204	390	1	drost	drost	PROPN
ct-9204	390	2	j	j	PROPN
ct-9204	390	3	,	,	PUNCT
ct-9204	390	4	karthaus	karthaus	PROPN
ct-9204	390	5	wr	wr	PROPN
ct-9204	390	6	,	,	PUNCT
ct-9204	390	7	gao	gao	PROPN
ct-9204	390	8	d	d	PROPN
ct-9204	390	9	,	,	PUNCT
ct-9204	390	10	et	et	PROPN
ct-9204	390	11	al	al	PROPN
ct-9204	390	12	:	:	PUNCT
ct-9204	390	13	organoid	organoid	PROPN
ct-9204	390	14	culture	culture	NOUN
ct-9204	390	15	systems	system	NOUN
ct-9204	390	16	for	for	ADP
ct-9204	390	17	prostate	prostate	NOUN
ct-9204	390	18	epithelial	epithelial	ADJ
ct-9204	390	19	and	and	CCONJ
ct-9204	390	20	cancer	cancer	NOUN
ct-9204	390	21	tissue	tissue	NOUN
ct-9204	390	22	.	.	PUNCT
ct-9204	391	1	nat	nat	NOUN
ct-9204	391	2	protoc	protoc	VERB
ct-9204	391	3	2016;11:347	2016;11:347	PROPN
ct-9204	391	4	-	-	NUM
ct-9204	391	5	358	358	NUM
ct-9204	391	6	.	.	PUNCT
ct-9204	392	1	117	117	NUM
ct-9204	392	2	.	.	PUNCT
ct-9204	393	1	moore	moore	PROPN
ct-9204	393	2	hd	hd	PROPN
ct-9204	393	3	,	,	PUNCT
ct-9204	393	4	curry	curry	PROPN
ct-9204	393	5	mr	mr	PROPN
ct-9204	393	6	,	,	PUNCT
ct-9204	393	7	penfold	penfold	PROPN
ct-9204	393	8	lm	lm	PROPN
ct-9204	393	9	,	,	PUNCT
ct-9204	393	10	et	et	PROPN
ct-9204	393	11	al	al	PROPN
ct-9204	393	12	:	:	PUNCT
ct-9204	393	13	the	the	DET
ct-9204	393	14	culture	culture	NOUN
ct-9204	393	15	of	of	ADP
ct-9204	393	16	human	human	ADJ
ct-9204	393	17	epididymal	epididymal	ADJ
ct-9204	393	18	epithelium	epithelium	NOUN
ct-9204	393	19	and	and	CCONJ
ct-9204	393	20	in	in	ADP
ct-9204	393	21	vitro	vitro	X
ct-9204	393	22	maturation	maturation	NOUN
ct-9204	393	23	of	of	ADP
ct-9204	393	24	epididymal	epididymal	ADJ
ct-9204	393	25	spermatozoa	spermatozoon	NOUN
ct-9204	393	26	.	.	PUNCT
ct-9204	394	1	fertil	fertil	AUX
ct-9204	394	2	steril	steril	VERB
ct-9204	394	3	1992;58:776	1992;58:776	NUM
ct-9204	394	4	-	-	PUNCT
ct-9204	394	5	783	783	NUM
ct-9204	394	6	.	.	PUNCT
ct-9204	395	1	clinical	clinical	ADJ
ct-9204	395	2	theriogenology	theriogenology	NOUN
ct-9204	395	3	•	•	NOUN
ct-9204	395	4	volume	volume	NOUN
ct-9204	395	5	12	12	NUM
ct-9204	395	6	number	number	NOUN
ct-9204	395	7	2	2	NUM
ct-9204	395	8	•	•	NOUN
ct-9204	395	9	june	june	PROPN
ct-9204	395	10	2020100	2020100	NUM
ct-9204	395	11	118	118	NUM
ct-9204	395	12	.	.	PUNCT
ct-9204	396	1	vader	vader	NOUN
ct-9204	396	2	p	p	X
ct-9204	396	3	,	,	PUNCT
ct-9204	396	4	mol	mol	X
ct-9204	396	5	ea	ea	PROPN
ct-9204	396	6	,	,	PUNCT
ct-9204	396	7	pasterkamp	pasterkamp	PROPN
ct-9204	396	8	g	g	PROPN
ct-9204	396	9	,	,	PUNCT
ct-9204	396	10	et	et	PROPN
ct-9204	396	11	al	al	PROPN
ct-9204	396	12	:	:	PUNCT
ct-9204	396	13	extracellular	extracellular	ADJ
ct-9204	396	14	vesicles	vesicle	NOUN
ct-9204	396	15	for	for	ADP
ct-9204	396	16	drug	drug	NOUN
ct-9204	396	17	delivery	delivery	NOUN
ct-9204	396	18	.	.	PUNCT
ct-9204	397	1	adv	adv	PROPN
ct-9204	397	2	drug	drug	NOUN
ct-9204	397	3	delivery	delivery	NOUN
ct-9204	397	4	rev	rev	VERB
ct-9204	397	5	2016;106:148	2016;106:148	NUM
ct-9204	397	6	-	-	SYM
ct-9204	397	7	156	156	NUM
ct-9204	397	8	.	.	PUNCT
ct-9204	398	1	119	119	NUM
ct-9204	398	2	.	.	PUNCT
ct-9204	399	1	batrakova	batrakova	PROPN
ct-9204	399	2	ev	ev	PROPN
ct-9204	399	3	,	,	PUNCT
ct-9204	399	4	kim	kim	PROPN
ct-9204	399	5	ms	ms	PROPN
ct-9204	399	6	:	:	PUNCT
ct-9204	399	7	using	use	VERB
ct-9204	399	8	exosomes	exosome	NOUN
ct-9204	399	9	,	,	PUNCT
ct-9204	399	10	naturally	naturally	ADV
ct-9204	399	11	-	-	PUNCT
ct-9204	399	12	equipped	equip	VERB
ct-9204	399	13	nanocarriers	nanocarrier	NOUN
ct-9204	399	14	,	,	PUNCT
ct-9204	399	15	for	for	ADP
ct-9204	399	16	drug	drug	NOUN
ct-9204	399	17	delivery	delivery	NOUN
ct-9204	399	18	.	.	PUNCT
ct-9204	400	1	j	j	PROPN
ct-9204	400	2	control	control	PROPN
ct-9204	400	3	release	release	PROPN
ct-9204	400	4	2015;219:396	2015;219:396	NUM
ct-9204	400	5	-	-	SYM
ct-9204	400	6	405	405	NUM
ct-9204	400	7	.	.	PUNCT
ct-9204	401	1	120	120	NUM
ct-9204	401	2	.	.	PUNCT
ct-9204	402	1	ohno	ohno	PROPN
ct-9204	402	2	s	s	NOUN
ct-9204	402	3	-	-	PUNCT
ct-9204	402	4	i	i	PROPN
ct-9204	402	5	,	,	PUNCT
ct-9204	402	6	drummen	drumman	NOUN
ct-9204	402	7	gp	gp	NOUN
ct-9204	402	8	,	,	PUNCT
ct-9204	402	9	kuroda	kuroda	PROPN
ct-9204	402	10	m	m	PROPN
ct-9204	402	11	:	:	PUNCT
ct-9204	402	12	focus	focus	VERB
ct-9204	402	13	on	on	ADP
ct-9204	402	14	extracellular	extracellular	ADJ
ct-9204	402	15	vesicles	vesicle	NOUN
ct-9204	402	16	:	:	PUNCT
ct-9204	402	17	development	development	NOUN
ct-9204	402	18	of	of	ADP
ct-9204	402	19	extracellular	extracellular	ADJ
ct-9204	402	20	vesicle	vesicle	NOUN
ct-9204	402	21	-	-	PUNCT
ct-9204	402	22	based	base	VERB
ct-9204	402	23	therapeutic	therapeutic	ADJ
ct-9204	402	24	systems	system	NOUN
ct-9204	402	25	.	.	PUNCT
ct-9204	403	1	int	int	PROPN
ct-9204	403	2	j	j	PROPN
ct-9204	403	3	mol	mol	ADP
ct-9204	403	4	sci	sci	PROPN
ct-9204	403	5	2016;17:172	2016;17:172	NUM
ct-9204	403	6	-	-	SYM
ct-9204	403	7	191	191	NUM
ct-9204	403	8	.	.	PUNCT
ct-9204	403	9	121	121	NUM
ct-9204	403	10	.	.	PUNCT
ct-9204	404	1	agrahari	agrahari	PROPN
ct-9204	404	2	v	v	PROPN
ct-9204	404	3	,	,	PUNCT
ct-9204	404	4	agrahari	agrahari	PROPN
ct-9204	404	5	v	v	NOUN
ct-9204	404	6	,	,	PUNCT
ct-9204	404	7	burnouf	burnouf	PROPN
ct-9204	404	8	p	p	NOUN
ct-9204	404	9	-	-	PUNCT
ct-9204	404	10	a	a	NOUN
ct-9204	404	11	,	,	PUNCT
ct-9204	404	12	et	et	PROPN
ct-9204	404	13	al	al	PROPN
ct-9204	404	14	:	:	PUNCT
ct-9204	404	15	extracellular	extracellular	ADJ
ct-9204	404	16	microvesicles	microvesicle	NOUN
ct-9204	404	17	as	as	ADP
ct-9204	404	18	new	new	ADJ
ct-9204	404	19	industrial	industrial	ADJ
ct-9204	404	20	therapeutic	therapeutic	ADJ
ct-9204	404	21	frontiers	frontier	NOUN
ct-9204	404	22	.	.	PUNCT
ct-9204	405	1	trends	trend	NOUN
ct-9204	405	2	biotechnol	biotechnol	VERB
ct-9204	405	3	2019;37:707	2019;37:707	NOUN
ct-9204	405	4	-	-	SYM
ct-9204	405	5	729	729	NUM
ct-9204	405	6	.	.	PUNCT
ct-9204	406	1	122	122	NUM
ct-9204	406	2	.	.	PUNCT
ct-9204	407	1	zhu	zhu	PROPN
ct-9204	407	2	l	l	NOUN
ct-9204	407	3	,	,	PUNCT
ct-9204	407	4	gangadaran	gangadaran	NOUN
ct-9204	407	5	p	p	NOUN
ct-9204	407	6	,	,	PUNCT
ct-9204	407	7	kalimuthu	kalimuthu	PROPN
ct-9204	407	8	s	s	PROPN
ct-9204	407	9	,	,	PUNCT
ct-9204	407	10	et	et	PROPN
ct-9204	407	11	al	al	PROPN
ct-9204	407	12	:	:	PUNCT
ct-9204	407	13	novel	novel	ADJ
ct-9204	407	14	alternatives	alternative	NOUN
ct-9204	407	15	to	to	ADP
ct-9204	407	16	extracellular	extracellular	ADJ
ct-9204	407	17	vesicle	vesicle	NOUN
ct-9204	407	18	-	-	PUNCT
ct-9204	407	19	based	base	VERB
ct-9204	407	20	immunotherapy	immunotherapy	NOUN
ct-9204	407	21	–	–	PUNCT
ct-9204	407	22	exosome	exosome	PROPN
ct-9204	407	23	mimetics	mimetic	NOUN
ct-9204	407	24	derived	derive	VERB
ct-9204	407	25	from	from	ADP
ct-9204	407	26	natural	natural	ADJ
ct-9204	407	27	killer	killer	NOUN
ct-9204	407	28	cells	cell	NOUN
ct-9204	407	29	.	.	PUNCT
ct-9204	408	1	artif	artif	NOUN
ct-9204	408	2	cells	cell	NOUN
ct-9204	408	3	nanomed	nanome	VERB
ct-9204	408	4	biotechnol	biotechnol	ADJ
ct-9204	408	5	2018;46	2018;46	NUM
ct-9204	408	6	:	:	PUNCT
ct-9204	408	7	s166	s166	PROPN
ct-9204	408	8	-	-	PUNCT
ct-9204	408	9	s179	s179	PROPN
ct-9204	408	10	.	.	PUNCT
ct-9204	409	1	123	123	NUM
ct-9204	409	2	.	.	PUNCT
ct-9204	410	1	gomzikova	gomzikova	PROPN
ct-9204	410	2	mo	mo	PROPN
ct-9204	410	3	,	,	PUNCT
ct-9204	410	4	zhuravleva	zhuravleva	PROPN
ct-9204	410	5	mn	mn	PROPN
ct-9204	410	6	,	,	PUNCT
ct-9204	410	7	miftakhova	miftakhova	PROPN
ct-9204	410	8	rr	rr	PROPN
ct-9204	410	9	,	,	PUNCT
ct-9204	410	10	et	et	PROPN
ct-9204	410	11	al	al	PROPN
ct-9204	410	12	:	:	PUNCT
ct-9204	410	13	cytochalasin	cytochalasin	PROPN
ct-9204	410	14	b	b	X
ct-9204	410	15	-	-	PUNCT
ct-9204	410	16	induced	induce	VERB
ct-9204	410	17	membrane	membrane	NOUN
ct-9204	410	18	vesicles	vesicle	NOUN
ct-9204	410	19	convey	convey	VERB
ct-9204	410	20	angiogenic	angiogenic	ADJ
ct-9204	410	21	activity	activity	NOUN
ct-9204	410	22	of	of	ADP
ct-9204	410	23	parental	parental	ADJ
ct-9204	410	24	cells	cell	NOUN
ct-9204	410	25	.	.	PUNCT
ct-9204	411	1	oncotarget	oncotarget	PROPN
ct-9204	411	2	2017;8:70496	2017;8:70496	NUM
ct-9204	411	3	.	.	PUNCT
ct-9204	412	1	124	124	NUM
ct-9204	412	2	.	.	PUNCT
ct-9204	413	1	gomzikova	gomzikova	PROPN
ct-9204	413	2	mo	mo	PROPN
ct-9204	413	3	,	,	PUNCT
ct-9204	413	4	zhuravleva	zhuravleva	PROPN
ct-9204	413	5	mn	mn	PROPN
ct-9204	413	6	,	,	PUNCT
ct-9204	413	7	vorobev	vorobev	ADJ
ct-9204	413	8	vv	vv	NOUN
ct-9204	413	9	,	,	PUNCT
ct-9204	413	10	et	et	PROPN
ct-9204	413	11	al	al	PROPN
ct-9204	413	12	:	:	PUNCT
ct-9204	413	13	angiogenic	angiogenic	ADJ
ct-9204	413	14	activity	activity	NOUN
ct-9204	413	15	of	of	ADP
ct-9204	413	16	cytochalasin	cytochalasin	PROPN
ct-9204	413	17	b	b	NOUN
ct-9204	413	18	-	-	PUNCT
ct-9204	413	19	induced	induced	ADJ
ct-9204	413	20	membrane	membrane	NOUN
ct-9204	413	21	vesicles	vesicle	NOUN
ct-9204	413	22	of	of	ADP
ct-9204	413	23	human	human	ADJ
ct-9204	413	24	mesenchymal	mesenchymal	NOUN
ct-9204	413	25	stem	stem	NOUN
ct-9204	413	26	cells	cell	NOUN
ct-9204	413	27	.	.	PUNCT
ct-9204	414	1	cells	cell	NOUN
ct-9204	414	2	2019;9:95	2019;9:95	NOUN
ct-9204	414	3	-	-	PUNCT
ct-9204	414	4	111	111	NUM
ct-9204	414	5	.	.	PUNCT
ct-9204	414	6	125	125	NUM
ct-9204	414	7	.	.	PUNCT
ct-9204	415	1	jhan	jhan	PROPN
ct-9204	415	2	y	y	PROPN
ct-9204	415	3	-	-	PUNCT
ct-9204	415	4	y	y	PROPN
ct-9204	415	5	,	,	PUNCT
ct-9204	415	6	prasca	prasca	PROPN
ct-9204	415	7	-	-	PUNCT
ct-9204	415	8	chamorro	chamorro	PROPN
ct-9204	415	9	d	d	PROPN
ct-9204	415	10	,	,	PUNCT
ct-9204	415	11	zuniga	zuniga	PROPN
ct-9204	415	12	gp	gp	PROPN
ct-9204	415	13	,	,	PUNCT
ct-9204	415	14	et	et	PROPN
ct-9204	415	15	al	al	PROPN
ct-9204	415	16	:	:	PUNCT
ct-9204	415	17	engineered	engineer	VERB
ct-9204	415	18	extracellular	extracellular	ADJ
ct-9204	415	19	vesicles	vesicle	NOUN
ct-9204	415	20	with	with	ADP
ct-9204	415	21	synthetic	synthetic	ADJ
ct-9204	415	22	lipids	lipid	NOUN
ct-9204	415	23	via	via	ADP
ct-9204	415	24	membrane	membrane	NOUN
ct-9204	415	25	fusion	fusion	NOUN
ct-9204	415	26	to	to	PART
ct-9204	415	27	establish	establish	VERB
ct-9204	415	28	efficient	efficient	ADJ
ct-9204	415	29	gene	gene	NOUN
ct-9204	415	30	delivery	delivery	NOUN
ct-9204	415	31	.	.	PUNCT
ct-9204	416	1	int	int	NOUN
ct-9204	416	2	j	j	PROPN
ct-9204	416	3	pharm	pharm	PROPN
ct-9204	416	4	2020;573:118802	2020;573:118802	NUM
ct-9204	416	5	.	.	PUNCT
ct-9204	417	1	126	126	NUM
ct-9204	417	2	.	.	PUNCT
ct-9204	418	1	sato	sato	PROPN
ct-9204	418	2	yt	yt	PROPN
ct-9204	418	3	,	,	PUNCT
ct-9204	418	4	umezaki	umezaki	PROPN
ct-9204	418	5	k	k	NOUN
ct-9204	418	6	,	,	PUNCT
ct-9204	418	7	sawada	sawada	PROPN
ct-9204	418	8	s	s	PROPN
ct-9204	418	9	,	,	PUNCT
ct-9204	418	10	et	et	PROPN
ct-9204	418	11	al	al	PROPN
ct-9204	418	12	:	:	PUNCT
ct-9204	418	13	engineering	engineer	VERB
ct-9204	418	14	hybrid	hybrid	ADJ
ct-9204	418	15	exosomes	exosome	NOUN
ct-9204	418	16	by	by	ADP
ct-9204	418	17	membrane	membrane	ADJ
ct-9204	418	18	fusion	fusion	NOUN
ct-9204	418	19	with	with	ADP
ct-9204	418	20	liposomes	liposome	NOUN
ct-9204	418	21	.	.	PUNCT
ct-9204	419	1	sci	sci	PROPN
ct-9204	419	2	rep	rep	PROPN
ct-9204	419	3	2016;6:21933	2016;6:21933	PROPN
ct-9204	419	4	.	.	PUNCT
ct-9204	420	1	127	127	NUM
ct-9204	420	2	.	.	PUNCT
ct-9204	421	1	rayamajhi	rayamajhi	PROPN
ct-9204	421	2	s	s	PROPN
ct-9204	421	3	,	,	PUNCT
ct-9204	421	4	nguyen	nguyen	PROPN
ct-9204	421	5	tdt	tdt	PROPN
ct-9204	421	6	,	,	PUNCT
ct-9204	421	7	marasini	marasini	PROPN
ct-9204	421	8	r	r	PROPN
ct-9204	421	9	,	,	PUNCT
ct-9204	421	10	et	et	PROPN
ct-9204	421	11	al	al	PROPN
ct-9204	421	12	:	:	PUNCT
ct-9204	421	13	macrophage	macrophage	ADJ
ct-9204	421	14	-	-	PUNCT
ct-9204	421	15	derived	derive	VERB
ct-9204	421	16	exosome	exosome	ADJ
ct-9204	421	17	-	-	PUNCT
ct-9204	421	18	mimetic	mimetic	ADJ
ct-9204	421	19	hybrid	hybrid	ADJ
ct-9204	421	20	vesicles	vesicle	NOUN
ct-9204	421	21	for	for	ADP
ct-9204	421	22	tumor	tumor	NOUN
ct-9204	421	23	targeted	target	VERB
ct-9204	421	24	drug	drug	NOUN
ct-9204	421	25	delivery	delivery	NOUN
ct-9204	421	26	.	.	PUNCT
ct-9204	422	1	acta	acta	PROPN
ct-9204	422	2	biomater	biomater	PROPN
ct-9204	422	3	2019;94:482	2019;94:482	NOUN
ct-9204	422	4	-	-	SYM
ct-9204	422	5	494	494	NUM
ct-9204	422	6	.	.	NOUN
ct-9204	422	7	128	128	NUM
ct-9204	422	8	.	.	PUNCT
ct-9204	423	1	rideau	rideau	PROPN
ct-9204	423	2	e	e	PROPN
ct-9204	423	3	,	,	PUNCT
ct-9204	423	4	dimova	dimova	X
ct-9204	423	5	r	r	X
ct-9204	423	6	,	,	PUNCT
ct-9204	423	7	schwille	schwille	NOUN
ct-9204	423	8	p	p	NOUN
ct-9204	423	9	,	,	PUNCT
ct-9204	423	10	et	et	PROPN
ct-9204	423	11	al	al	PROPN
ct-9204	423	12	:	:	PUNCT
ct-9204	423	13	liposomes	liposome	NOUN
ct-9204	423	14	and	and	CCONJ
ct-9204	423	15	polymersomes	polymersome	NOUN
ct-9204	423	16	:	:	PUNCT
ct-9204	423	17	a	a	DET
ct-9204	423	18	comparative	comparative	ADJ
ct-9204	423	19	review	review	NOUN
ct-9204	423	20	towards	towards	ADP
ct-9204	423	21	cell	cell	NOUN
ct-9204	423	22	mimicking	mimic	VERB
ct-9204	423	23	.	.	PUNCT
ct-9204	424	1	chem	chem	NOUN
ct-9204	424	2	soc	soc	NOUN
ct-9204	424	3	rev	rev	VERB
ct-9204	424	4	2018;47:8572	2018;47:8572	PROPN
ct-9204	424	5	-	-	SYM
ct-9204	424	6	8610	8610	NUM
ct-9204	424	7	.	.	PUNCT
ct-9204	425	1	clinical	clinical	ADJ
ct-9204	425	2	theriogenology	theriogenology	NOUN
ct-9204	425	3	•	•	NOUN
ct-9204	425	4	volume	volume	NOUN
ct-9204	425	5	12	12	NUM
ct-9204	425	6	number	number	NOUN
ct-9204	425	7	2	2	NUM
ct-9204	425	8	•	•	NOUN
ct-9204	425	9	june	june	PROPN
ct-9204	425	10	2020	2020	NUM
ct-9204	425	11	101	101	NUM