id	sid	tid	token	lemma	pos
ct-9228	1	1	stem	stem	NOUN
ct-9228	1	2	cells	cell	NOUN
ct-9228	1	3	:	:	PUNCT
ct-9228	2	1	what	what	PRON
ct-9228	2	2	,	,	PUNCT
ct-9228	2	3	how	how	SCONJ
ct-9228	2	4	,	,	PUNCT
ct-9228	2	5	and	and	CCONJ
ct-9228	2	6	why	why	SCONJ
ct-9228	2	7	?	?	PUNCT
ct-9228	3	1	stem	stem	NOUN
ct-9228	3	2	cells	cell	NOUN
ct-9228	3	3	:	:	PUNCT
ct-9228	4	1	what	what	PRON
ct-9228	4	2	,	,	PUNCT
ct-9228	4	3	how	how	SCONJ
ct-9228	4	4	,	,	PUNCT
ct-9228	4	5	and	and	CCONJ
ct-9228	4	6	why	why	SCONJ
ct-9228	4	7	?	?	PUNCT
ct-9228	5	1	diane	diane	PROPN
ct-9228	5	2	carlisle	carlisle	PROPN
ct-9228	5	3	department	department	PROPN
ct-9228	5	4	of	of	ADP
ct-9228	5	5	neurological	neurological	ADJ
ct-9228	5	6	surgery	surgery	NOUN
ct-9228	5	7	,	,	PUNCT
ct-9228	5	8	university	university	NOUN
ct-9228	5	9	of	of	ADP
ct-9228	5	10	pittsburgh	pittsburgh	PROPN
ct-9228	5	11	,	,	PUNCT
ct-9228	5	12	pittsburgh	pittsburgh	PROPN
ct-9228	5	13	,	,	PUNCT
ct-9228	5	14	pa	pa	PROPN
ct-9228	5	15	abstract	abstract	ADJ
ct-9228	5	16	the	the	DET
ct-9228	5	17	use	use	NOUN
ct-9228	5	18	of	of	ADP
ct-9228	5	19	stem	stem	NOUN
ct-9228	5	20	cells	cell	NOUN
ct-9228	5	21	clinically	clinically	ADV
ct-9228	5	22	has	have	VERB
ct-9228	5	23	a	a	DET
ct-9228	5	24	solid	solid	ADJ
ct-9228	5	25	history	history	NOUN
ct-9228	5	26	and	and	CCONJ
ct-9228	5	27	also	also	ADV
ct-9228	5	28	broad	broad	ADJ
ct-9228	5	29	undeveloped	undeveloped	ADJ
ct-9228	5	30	potential	potential	NOUN
ct-9228	5	31	.	.	PUNCT
ct-9228	6	1	as	as	SCONJ
ct-9228	6	2	we	we	PRON
ct-9228	6	3	learn	learn	VERB
ct-9228	6	4	more	more	ADJ
ct-9228	6	5	about	about	ADP
ct-9228	6	6	these	these	DET
ct-9228	6	7	cells	cell	NOUN
ct-9228	6	8	and	and	CCONJ
ct-9228	6	9	their	their	PRON
ct-9228	6	10	properties	property	NOUN
ct-9228	6	11	,	,	PUNCT
ct-9228	6	12	our	our	PRON
ct-9228	6	13	ability	ability	NOUN
ct-9228	6	14	to	to	PART
ct-9228	6	15	harness	harness	VERB
ct-9228	6	16	their	their	PRON
ct-9228	6	17	potential	potential	NOUN
ct-9228	6	18	for	for	ADP
ct-9228	6	19	future	future	ADJ
ct-9228	6	20	benefit	benefit	NOUN
ct-9228	6	21	will	will	AUX
ct-9228	6	22	grow	grow	VERB
ct-9228	6	23	.	.	PUNCT
ct-9228	7	1	however	however	ADV
ct-9228	7	2	,	,	PUNCT
ct-9228	7	3	there	there	PRON
ct-9228	7	4	is	be	VERB
ct-9228	7	5	also	also	ADV
ct-9228	7	6	significant	significant	ADJ
ct-9228	7	7	confusion	confusion	NOUN
ct-9228	7	8	surrounding	surround	VERB
ct-9228	7	9	discussions	discussion	NOUN
ct-9228	7	10	of	of	ADP
ct-9228	7	11	stem	stem	NOUN
ct-9228	7	12	cells	cell	NOUN
ct-9228	7	13	,	,	PUNCT
ct-9228	7	14	due	due	ADJ
ct-9228	7	15	to	to	ADP
ct-9228	7	16	vague	vague	ADJ
ct-9228	7	17	definitions	definition	NOUN
ct-9228	7	18	regarding	regard	VERB
ct-9228	7	19	the	the	DET
ct-9228	7	20	types	type	NOUN
ct-9228	7	21	of	of	ADP
ct-9228	7	22	stem	stem	NOUN
ct-9228	7	23	cells	cell	NOUN
ct-9228	7	24	and	and	CCONJ
ct-9228	7	25	controversies	controversy	NOUN
ct-9228	7	26	that	that	PRON
ct-9228	7	27	are	be	AUX
ct-9228	7	28	inherent	inherent	ADJ
ct-9228	7	29	in	in	ADP
ct-9228	7	30	the	the	DET
ct-9228	7	31	uses	use	NOUN
ct-9228	7	32	of	of	ADP
ct-9228	7	33	some	some	DET
ct-9228	7	34	types	type	NOUN
ct-9228	7	35	of	of	ADP
ct-9228	7	36	stem	stem	NOUN
ct-9228	7	37	cells	cell	NOUN
ct-9228	7	38	.	.	PUNCT
ct-9228	8	1	this	this	DET
ct-9228	8	2	review	review	NOUN
ct-9228	8	3	discusses	discuss	VERB
ct-9228	8	4	the	the	DET
ct-9228	8	5	types	type	NOUN
ct-9228	8	6	of	of	ADP
ct-9228	8	7	stem	stem	NOUN
ct-9228	8	8	cells	cell	NOUN
ct-9228	8	9	,	,	PUNCT
ct-9228	8	10	their	their	PRON
ct-9228	8	11	advantages	advantage	NOUN
ct-9228	8	12	and	and	CCONJ
ct-9228	8	13	disadvantages	disadvantage	NOUN
ct-9228	8	14	,	,	PUNCT
ct-9228	8	15	and	and	CCONJ
ct-9228	8	16	how	how	SCONJ
ct-9228	8	17	they	they	PRON
ct-9228	8	18	can	can	AUX
ct-9228	8	19	be	be	AUX
ct-9228	8	20	used	use	VERB
ct-9228	8	21	clinically	clinically	ADV
ct-9228	8	22	and	and	CCONJ
ct-9228	8	23	for	for	ADP
ct-9228	8	24	research	research	NOUN
ct-9228	8	25	.	.	PUNCT
ct-9228	9	1	specifically	specifically	ADV
ct-9228	9	2	,	,	PUNCT
ct-9228	9	3	the	the	DET
ct-9228	9	4	differences	difference	NOUN
ct-9228	9	5	between	between	ADP
ct-9228	9	6	various	various	ADJ
ct-9228	9	7	/	/	SYM
ct-9228	9	8	common	common	ADJ
ct-9228	9	9	types	type	NOUN
ct-9228	9	10	of	of	ADP
ct-9228	9	11	pluripotent	pluripotent	ADJ
ct-9228	9	12	stem	stem	NOUN
ct-9228	9	13	cells	cell	NOUN
ct-9228	9	14	is	be	AUX
ct-9228	9	15	discussed	discuss	VERB
ct-9228	9	16	.	.	PUNCT
ct-9228	10	1	the	the	DET
ct-9228	10	2	utility	utility	NOUN
ct-9228	10	3	of	of	ADP
ct-9228	10	4	pluripotent	pluripotent	ADJ
ct-9228	10	5	stem	stem	NOUN
ct-9228	10	6	cells	cell	NOUN
ct-9228	10	7	compared	compare	VERB
ct-9228	10	8	to	to	ADP
ct-9228	10	9	lineage	lineage	NOUN
ct-9228	10	10	restricted	restrict	VERB
ct-9228	10	11	stem	stem	NOUN
ct-9228	10	12	cells	cell	NOUN
ct-9228	10	13	is	be	AUX
ct-9228	10	14	also	also	ADV
ct-9228	10	15	considered	consider	VERB
ct-9228	10	16	.	.	PUNCT
ct-9228	11	1	keywords	keyword	NOUN
ct-9228	11	2	:	:	PUNCT
ct-9228	11	3	pluripotent	pluripotent	ADJ
ct-9228	11	4	stem	stem	NOUN
ct-9228	11	5	cells	cell	NOUN
ct-9228	11	6	,	,	PUNCT
ct-9228	11	7	embryonic	embryonic	ADJ
ct-9228	11	8	stem	stem	NOUN
ct-9228	11	9	cells	cell	NOUN
ct-9228	11	10	,	,	PUNCT
ct-9228	11	11	tissue	tissue	NOUN
ct-9228	11	12	-	-	PUNCT
ct-9228	11	13	specific	specific	ADJ
ct-9228	11	14	stem	stem	NOUN
ct-9228	11	15	cells	cell	NOUN
ct-9228	11	16	,	,	PUNCT
ct-9228	11	17	directed	direct	VERB
ct-9228	11	18	differentiation	differentiation	NOUN
ct-9228	11	19	introduction	introduction	NOUN
ct-9228	11	20	although	although	SCONJ
ct-9228	11	21	there	there	PRON
ct-9228	11	22	are	be	VERB
ct-9228	11	23	several	several	ADJ
ct-9228	11	24	kinds	kind	NOUN
ct-9228	11	25	of	of	ADP
ct-9228	11	26	stem	stem	NOUN
ct-9228	11	27	cells	cell	NOUN
ct-9228	11	28	,	,	PUNCT
ct-9228	11	29	in	in	ADP
ct-9228	11	30	scientific	scientific	ADJ
ct-9228	11	31	and	and	CCONJ
ct-9228	11	32	lay	lie	VERB
ct-9228	11	33	conversations	conversation	NOUN
ct-9228	11	34	,	,	PUNCT
ct-9228	11	35	often	often	ADV
ct-9228	11	36	the	the	DET
ct-9228	11	37	term	term	NOUN
ct-9228	11	38	‘	'	PUNCT
ct-9228	11	39	stem	stem	NOUN
ct-9228	11	40	cells	cell	NOUN
ct-9228	11	41	’	'	PUNCT
ct-9228	11	42	is	be	AUX
ct-9228	11	43	used	use	VERB
ct-9228	11	44	without	without	ADP
ct-9228	11	45	specificity	specificity	NOUN
ct-9228	11	46	,	,	PUNCT
ct-9228	11	47	which	which	PRON
ct-9228	11	48	can	can	AUX
ct-9228	11	49	lead	lead	VERB
ct-9228	11	50	to	to	ADP
ct-9228	11	51	confusion	confusion	NOUN
ct-9228	11	52	and	and	CCONJ
ct-9228	11	53	misunderstanding	misunderstanding	NOUN
ct-9228	11	54	.	.	PUNCT
ct-9228	12	1	this	this	DET
ct-9228	12	2	review	review	NOUN
ct-9228	12	3	focuses	focus	VERB
ct-9228	12	4	on	on	ADP
ct-9228	12	5	the	the	DET
ct-9228	12	6	major	major	ADJ
ct-9228	12	7	types	type	NOUN
ct-9228	12	8	of	of	ADP
ct-9228	12	9	stem	stem	NOUN
ct-9228	12	10	cells	cell	NOUN
ct-9228	12	11	,	,	PUNCT
ct-9228	12	12	including	include	VERB
ct-9228	12	13	the	the	DET
ct-9228	12	14	types	type	NOUN
ct-9228	12	15	of	of	ADP
ct-9228	12	16	pluripotent	pluripotent	ADJ
ct-9228	12	17	stem	stem	NOUN
ct-9228	12	18	cells	cell	NOUN
ct-9228	12	19	,	,	PUNCT
ct-9228	12	20	as	as	ADV
ct-9228	12	21	well	well	ADV
ct-9228	12	22	as	as	ADP
ct-9228	12	23	lineagerestricted	lineagerestricte	VERB
ct-9228	12	24	stem	stem	NOUN
ct-9228	12	25	cells	cell	NOUN
ct-9228	12	26	,	,	PUNCT
ct-9228	12	27	their	their	PRON
ct-9228	12	28	advantages	advantage	NOUN
ct-9228	12	29	and	and	CCONJ
ct-9228	12	30	disadvantages	disadvantage	NOUN
ct-9228	12	31	,	,	PUNCT
ct-9228	12	32	and	and	CCONJ
ct-9228	12	33	their	their	PRON
ct-9228	12	34	uses	use	NOUN
ct-9228	12	35	in	in	ADP
ct-9228	12	36	the	the	DET
ct-9228	12	37	clinic	clinic	NOUN
ct-9228	12	38	and	and	CCONJ
ct-9228	12	39	in	in	ADP
ct-9228	12	40	the	the	DET
ct-9228	12	41	laboratory	laboratory	NOUN
ct-9228	12	42	.	.	PUNCT
ct-9228	13	1	types	type	NOUN
ct-9228	13	2	of	of	ADP
ct-9228	13	3	stem	stem	NOUN
ct-9228	13	4	cells	cell	NOUN
ct-9228	13	5	before	before	ADP
ct-9228	13	6	discussion	discussion	NOUN
ct-9228	13	7	of	of	ADP
ct-9228	13	8	the	the	DET
ct-9228	13	9	characteristics	characteristic	NOUN
ct-9228	13	10	of	of	ADP
ct-9228	13	11	stem	stem	NOUN
ct-9228	13	12	cells	cell	NOUN
ct-9228	13	13	,	,	PUNCT
ct-9228	13	14	their	their	PRON
ct-9228	13	15	advantages	advantage	NOUN
ct-9228	13	16	and	and	CCONJ
ct-9228	13	17	disadvantages	disadvantage	NOUN
ct-9228	13	18	,	,	PUNCT
ct-9228	13	19	and	and	CCONJ
ct-9228	13	20	their	their	PRON
ct-9228	13	21	clinical	clinical	ADJ
ct-9228	13	22	and	and	CCONJ
ct-9228	13	23	research	research	NOUN
ct-9228	13	24	uses	use	NOUN
ct-9228	13	25	,	,	PUNCT
ct-9228	13	26	it	it	PRON
ct-9228	13	27	is	be	AUX
ct-9228	13	28	important	important	ADJ
ct-9228	13	29	to	to	PART
ct-9228	13	30	clarify	clarify	VERB
ct-9228	13	31	the	the	DET
ct-9228	13	32	types	type	NOUN
ct-9228	13	33	of	of	ADP
ct-9228	13	34	stem	stem	NOUN
ct-9228	13	35	cells	cell	NOUN
ct-9228	13	36	.	.	PUNCT
ct-9228	14	1	in	in	ADP
ct-9228	14	2	general	general	ADJ
ct-9228	14	3	,	,	PUNCT
ct-9228	14	4	there	there	PRON
ct-9228	14	5	are	be	VERB
ct-9228	14	6	3	3	NUM
ct-9228	14	7	major	major	ADJ
ct-9228	14	8	types	type	NOUN
ct-9228	14	9	of	of	ADP
ct-9228	14	10	stem	stem	NOUN
ct-9228	14	11	cells	cell	NOUN
ct-9228	14	12	:	:	PUNCT
ct-9228	14	13	pluripotent	pluripotent	ADJ
ct-9228	14	14	stem	stem	NOUN
ct-9228	14	15	cells	cell	NOUN
ct-9228	14	16	,	,	PUNCT
ct-9228	14	17	lineage	lineage	NOUN
ct-9228	14	18	restricted	restrict	VERB
ct-9228	14	19	or	or	CCONJ
ct-9228	14	20	somatic	somatic	ADJ
ct-9228	14	21	stem	stem	NOUN
ct-9228	14	22	cells	cell	NOUN
ct-9228	14	23	,	,	PUNCT
ct-9228	14	24	and	and	CCONJ
ct-9228	14	25	totipotent	totipotent	ADJ
ct-9228	14	26	stem	stem	NOUN
ct-9228	14	27	cells	cell	NOUN
ct-9228	14	28	.	.	PUNCT
ct-9228	15	1	pluripotent	pluripotent	ADJ
ct-9228	15	2	stem	stem	NOUN
ct-9228	15	3	cells	cell	NOUN
ct-9228	15	4	are	be	AUX
ct-9228	15	5	the	the	DET
ct-9228	15	6	most	most	ADV
ct-9228	15	7	versatile	versatile	ADJ
ct-9228	15	8	of	of	ADP
ct-9228	15	9	stem	stem	NOUN
ct-9228	15	10	cells	cell	NOUN
ct-9228	15	11	.	.	PUNCT
ct-9228	16	1	these	these	DET
ct-9228	16	2	cells	cell	NOUN
ct-9228	16	3	are	be	AUX
ct-9228	16	4	named	name	VERB
ct-9228	16	5	as	as	ADV
ct-9228	16	6	such	such	ADJ
ct-9228	16	7	because	because	SCONJ
ct-9228	16	8	they	they	PRON
ct-9228	16	9	have	have	VERB
ct-9228	16	10	the	the	DET
ct-9228	16	11	potential	potential	NOUN
ct-9228	16	12	to	to	PART
ct-9228	16	13	become	become	VERB
ct-9228	16	14	any	any	DET
ct-9228	16	15	cell	cell	NOUN
ct-9228	16	16	type	type	NOUN
ct-9228	16	17	that	that	PRON
ct-9228	16	18	develops	develop	VERB
ct-9228	16	19	from	from	ADP
ct-9228	16	20	an	an	DET
ct-9228	16	21	embryo	embryo	NOUN
ct-9228	16	22	.	.	PUNCT
ct-9228	17	1	indeed	indeed	ADV
ct-9228	17	2	,	,	PUNCT
ct-9228	17	3	the	the	DET
ct-9228	17	4	classic	classic	ADJ
ct-9228	17	5	type	type	NOUN
ct-9228	17	6	of	of	ADP
ct-9228	17	7	pluripotent	pluripotent	ADJ
ct-9228	17	8	stem	stem	NOUN
ct-9228	17	9	cell	cell	NOUN
ct-9228	17	10	is	be	AUX
ct-9228	17	11	the	the	DET
ct-9228	17	12	embryonic	embryonic	ADJ
ct-9228	17	13	stem	stem	NOUN
ct-9228	17	14	cell	cell	NOUN
ct-9228	17	15	.	.	PUNCT
ct-9228	18	1	other	other	ADJ
ct-9228	18	2	sources	source	NOUN
ct-9228	18	3	of	of	ADP
ct-9228	18	4	pluripotent	pluripotent	ADJ
ct-9228	18	5	stem	stem	NOUN
ct-9228	18	6	cells	cell	NOUN
ct-9228	18	7	are	be	AUX
ct-9228	18	8	somatic	somatic	ADJ
ct-9228	18	9	cell	cell	NOUN
ct-9228	18	10	nuclear	nuclear	ADJ
ct-9228	18	11	transfer	transfer	NOUN
ct-9228	18	12	stem	stem	NOUN
ct-9228	18	13	cells	cell	NOUN
ct-9228	18	14	and	and	CCONJ
ct-9228	18	15	induced	induce	VERB
ct-9228	18	16	pluripotent	pluripotent	ADJ
ct-9228	18	17	stem	stem	NOUN
ct-9228	18	18	cells	cell	NOUN
ct-9228	18	19	.	.	PUNCT
ct-9228	19	1	beyond	beyond	ADP
ct-9228	19	2	the	the	DET
ct-9228	19	3	ability	ability	NOUN
ct-9228	19	4	to	to	PART
ct-9228	19	5	differentiate	differentiate	VERB
ct-9228	19	6	into	into	ADP
ct-9228	19	7	any	any	DET
ct-9228	19	8	cell	cell	NOUN
ct-9228	19	9	type	type	NOUN
ct-9228	19	10	in	in	ADP
ct-9228	19	11	an	an	DET
ct-9228	19	12	embryo	embryo	NOUN
ct-9228	19	13	,	,	PUNCT
ct-9228	19	14	pluripotent	pluripotent	ADJ
ct-9228	19	15	stem	stem	NOUN
ct-9228	19	16	cell	cell	NOUN
ct-9228	19	17	lines	line	NOUN
ct-9228	19	18	are	be	AUX
ct-9228	19	19	immortal	immortal	ADJ
ct-9228	19	20	,	,	PUNCT
ct-9228	19	21	with	with	ADP
ct-9228	19	22	unlimited	unlimited	ADJ
ct-9228	19	23	proliferation	proliferation	NOUN
ct-9228	19	24	potential	potential	NOUN
ct-9228	19	25	.	.	PUNCT
ct-9228	20	1	embryonic	embryonic	ADJ
ct-9228	20	2	stem	stem	NOUN
ct-9228	20	3	cells	cell	NOUN
ct-9228	20	4	embryonic	embryonic	ADJ
ct-9228	20	5	stem	stem	NOUN
ct-9228	20	6	cells	cell	NOUN
ct-9228	20	7	are	be	AUX
ct-9228	20	8	derived	derive	VERB
ct-9228	20	9	by	by	ADP
ct-9228	20	10	dissecting	dissect	VERB
ct-9228	20	11	and	and	CCONJ
ct-9228	20	12	growing	grow	VERB
ct-9228	20	13	the	the	DET
ct-9228	20	14	cells	cell	NOUN
ct-9228	20	15	that	that	PRON
ct-9228	20	16	would	would	AUX
ct-9228	20	17	become	become	VERB
ct-9228	20	18	the	the	DET
ct-9228	20	19	embryo	embryo	NOUN
ct-9228	20	20	from	from	ADP
ct-9228	20	21	a	a	DET
ct-9228	20	22	blastocyst	blastocyst	NOUN
ct-9228	20	23	stage	stage	NOUN
ct-9228	20	24	embryo	embryo	NOUN
ct-9228	20	25	,	,	PUNCT
ct-9228	20	26	before	before	ADP
ct-9228	20	27	any	any	DET
ct-9228	20	28	differentiation	differentiation	NOUN
ct-9228	20	29	into	into	ADP
ct-9228	20	30	germ	germ	NOUN
ct-9228	20	31	layers	layer	NOUN
ct-9228	20	32	begins.1	begins.1	VERB
ct-9228	20	33	-	-	PUNCT
ct-9228	20	34	3	3	NUM
ct-9228	20	35	human	human	ADJ
ct-9228	20	36	embryonic	embryonic	ADJ
ct-9228	20	37	stem	stem	NOUN
ct-9228	20	38	cells	cell	NOUN
ct-9228	20	39	cells	cell	NOUN
ct-9228	20	40	drew	draw	VERB
ct-9228	20	41	significant	significant	ADJ
ct-9228	20	42	public	public	ADJ
ct-9228	20	43	attention	attention	NOUN
ct-9228	20	44	upon	upon	SCONJ
ct-9228	20	45	publication	publication	NOUN
ct-9228	20	46	in	in	ADP
ct-9228	20	47	1998,3	1998,3	NUM
ct-9228	20	48	because	because	SCONJ
ct-9228	20	49	they	they	PRON
ct-9228	20	50	are	be	AUX
ct-9228	20	51	generated	generate	VERB
ct-9228	20	52	from	from	ADP
ct-9228	20	53	human	human	ADJ
ct-9228	20	54	embryos	embryo	NOUN
ct-9228	20	55	after	after	ADP
ct-9228	20	56	in	in	ADP
ct-9228	20	57	vitro	vitro	X
ct-9228	20	58	fertilization	fertilization	NOUN
ct-9228	20	59	.	.	PUNCT
ct-9228	21	1	however	however	ADV
ct-9228	21	2	,	,	PUNCT
ct-9228	21	3	embryonic	embryonic	ADJ
ct-9228	21	4	stem	stem	NOUN
ct-9228	21	5	cells	cell	NOUN
ct-9228	21	6	generated	generate	VERB
ct-9228	21	7	from	from	ADP
ct-9228	21	8	other	other	ADJ
ct-9228	21	9	animals	animal	NOUN
ct-9228	21	10	were	be	AUX
ct-9228	21	11	in	in	ADP
ct-9228	21	12	existence	existence	NOUN
ct-9228	21	13	for	for	ADP
ct-9228	21	14	more	more	ADJ
ct-9228	21	15	than	than	ADP
ct-9228	21	16	a	a	PRON
ct-9228	21	17	decade	decade	NOUN
ct-9228	21	18	before	before	ADP
ct-9228	21	19	the	the	DET
ct-9228	21	20	generation	generation	NOUN
ct-9228	21	21	of	of	ADP
ct-9228	21	22	human	human	ADJ
ct-9228	21	23	embryonic	embryonic	ADJ
ct-9228	21	24	stem	stem	NOUN
ct-9228	21	25	cells	cell	NOUN
ct-9228	21	26	by	by	ADP
ct-9228	21	27	the	the	DET
ct-9228	21	28	thomson	thomson	PROPN
ct-9228	21	29	group	group	NOUN
ct-9228	21	30	.	.	PUNCT
ct-9228	22	1	mouse	mouse	NOUN
ct-9228	22	2	embryonic	embryonic	ADJ
ct-9228	22	3	stem	stem	NOUN
ct-9228	22	4	cells	cell	NOUN
ct-9228	22	5	were	be	AUX
ct-9228	22	6	first	first	ADV
ct-9228	22	7	published	publish	VERB
ct-9228	22	8	in	in	ADP
ct-9228	22	9	1981,1	1981,1	NUM
ct-9228	22	10	and	and	CCONJ
ct-9228	22	11	other	other	ADJ
ct-9228	22	12	animal	animal	NOUN
ct-9228	22	13	species	specie	NOUN
ct-9228	22	14	followed.3	followed.3	ADJ
ct-9228	22	15	-	-	SYM
ct-9228	22	16	6	6	NUM
ct-9228	22	17	somatic	somatic	ADJ
ct-9228	22	18	cell	cell	NOUN
ct-9228	22	19	nuclear	nuclear	ADJ
ct-9228	22	20	transfer	transfer	NOUN
ct-9228	22	21	stem	stem	NOUN
ct-9228	22	22	cells	cell	NOUN
ct-9228	22	23	somatic	somatic	ADJ
ct-9228	22	24	cell	cell	NOUN
ct-9228	22	25	nuclear	nuclear	ADJ
ct-9228	22	26	transfer	transfer	NOUN
ct-9228	22	27	can	can	AUX
ct-9228	22	28	also	also	ADV
ct-9228	22	29	be	be	AUX
ct-9228	22	30	used	use	VERB
ct-9228	22	31	to	to	PART
ct-9228	22	32	generate	generate	VERB
ct-9228	22	33	embryos	embryo	NOUN
ct-9228	22	34	for	for	ADP
ct-9228	22	35	the	the	DET
ct-9228	22	36	production	production	NOUN
ct-9228	22	37	of	of	ADP
ct-9228	22	38	pluripotent	pluripotent	ADJ
ct-9228	22	39	stem	stem	NOUN
ct-9228	22	40	cells	cell	NOUN
ct-9228	22	41	.	.	PUNCT
ct-9228	23	1	these	these	DET
ct-9228	23	2	cells	cell	NOUN
ct-9228	23	3	are	be	AUX
ct-9228	23	4	generated	generate	VERB
ct-9228	23	5	by	by	ADP
ct-9228	23	6	removing	remove	VERB
ct-9228	23	7	the	the	DET
ct-9228	23	8	haploid	haploid	NOUN
ct-9228	23	9	nucleus	nucleus	NOUN
ct-9228	23	10	from	from	ADP
ct-9228	23	11	an	an	DET
ct-9228	23	12	oocyte	oocyte	NOUN
ct-9228	23	13	,	,	PUNCT
ct-9228	23	14	transferring	transfer	VERB
ct-9228	23	15	in	in	ADP
ct-9228	23	16	the	the	DET
ct-9228	23	17	diploid	diploid	ADJ
ct-9228	23	18	nucleus	nucleus	NOUN
ct-9228	23	19	from	from	ADP
ct-9228	23	20	a	a	DET
ct-9228	23	21	somatic	somatic	ADJ
ct-9228	23	22	cell	cell	NOUN
ct-9228	23	23	,	,	PUNCT
ct-9228	23	24	followed	follow	VERB
ct-9228	23	25	by	by	ADP
ct-9228	23	26	chemical	chemical	ADJ
ct-9228	23	27	activation	activation	NOUN
ct-9228	23	28	of	of	ADP
ct-9228	23	29	the	the	DET
ct-9228	23	30	oocyte.7	oocyte.7	PROPN
ct-9228	23	31	-	-	PUNCT
ct-9228	23	32	11	11	NUM
ct-9228	23	33	like	like	ADP
ct-9228	23	34	embryonic	embryonic	ADJ
ct-9228	23	35	stem	stem	NOUN
ct-9228	23	36	cells	cell	NOUN
ct-9228	23	37	,	,	PUNCT
ct-9228	23	38	human	human	ADJ
ct-9228	23	39	somatic	somatic	ADJ
ct-9228	23	40	cell	cell	NOUN
ct-9228	23	41	nuclear	nuclear	ADJ
ct-9228	23	42	transfer	transfer	NOUN
ct-9228	23	43	cells	cell	NOUN
ct-9228	23	44	are	be	AUX
ct-9228	23	45	highly	highly	ADV
ct-9228	23	46	controversial	controversial	ADJ
ct-9228	23	47	.	.	PUNCT
ct-9228	24	1	first	first	ADV
ct-9228	24	2	,	,	PUNCT
ct-9228	24	3	they	they	PRON
ct-9228	24	4	are	be	AUX
ct-9228	24	5	controversial	controversial	ADJ
ct-9228	24	6	because	because	SCONJ
ct-9228	24	7	they	they	PRON
ct-9228	24	8	can	can	AUX
ct-9228	24	9	also	also	ADV
ct-9228	24	10	be	be	AUX
ct-9228	24	11	used	use	VERB
ct-9228	24	12	for	for	ADP
ct-9228	24	13	reproductive	reproductive	ADJ
ct-9228	24	14	cloning	cloning	NOUN
ct-9228	24	15	,	,	PUNCT
ct-9228	24	16	as	as	SCONJ
ct-9228	24	17	first	first	ADV
ct-9228	24	18	publicized	publicize	VERB
ct-9228	24	19	by	by	ADP
ct-9228	24	20	dolly	dolly	ADV
ct-9228	24	21	the	the	DET
ct-9228	24	22	sheep.12	sheep.12	NOUN
ct-9228	24	23	second	second	ADJ
ct-9228	24	24	,	,	PUNCT
ct-9228	24	25	much	much	ADV
ct-9228	24	26	like	like	ADP
ct-9228	24	27	human	human	ADJ
ct-9228	24	28	embryonic	embryonic	ADJ
ct-9228	24	29	stem	stem	NOUN
ct-9228	24	30	cells	cell	NOUN
ct-9228	24	31	,	,	PUNCT
ct-9228	24	32	the	the	DET
ct-9228	24	33	method	method	NOUN
ct-9228	24	34	involves	involve	VERB
ct-9228	24	35	the	the	DET
ct-9228	24	36	production	production	NOUN
ct-9228	24	37	of	of	ADP
ct-9228	24	38	an	an	DET
ct-9228	24	39	early	early	ADJ
ct-9228	24	40	blastocyst	blastocyst	NOUN
ct-9228	24	41	from	from	ADP
ct-9228	24	42	which	which	PRON
ct-9228	24	43	the	the	DET
ct-9228	24	44	pluripotent	pluripotent	ADJ
ct-9228	24	45	stem	stem	NOUN
ct-9228	24	46	cells	cell	NOUN
ct-9228	24	47	are	be	AUX
ct-9228	24	48	obtained.13	obtained.13	NUM
ct-9228	24	49	although	although	SCONJ
ct-9228	24	50	human	human	ADJ
ct-9228	24	51	reproductive	reproductive	ADJ
ct-9228	24	52	cloning	cloning	NOUN
ct-9228	24	53	has	have	VERB
ct-9228	24	54	clinical	clinical	ADJ
ct-9228	24	55	theriogenology	theriogenology	NOUN
ct-9228	25	1	•	•	NOUN
ct-9228	25	2	volume	volume	NOUN
ct-9228	25	3	12	12	NUM
ct-9228	25	4	number	number	NOUN
ct-9228	25	5	3	3	NUM
ct-9228	25	6	•	•	NUM
ct-9228	25	7	september	september	PROPN
ct-9228	25	8	2020	2020	NUM
ct-9228	25	9	183	183	NUM
ct-9228	25	10	not	not	PART
ct-9228	25	11	been	be	AUX
ct-9228	25	12	achieved	achieve	VERB
ct-9228	25	13	for	for	ADP
ct-9228	25	14	ethical	ethical	ADJ
ct-9228	25	15	reasons	reason	NOUN
ct-9228	25	16	,	,	PUNCT
ct-9228	25	17	cloned	clone	VERB
ct-9228	25	18	nonhuman	nonhuman	ADJ
ct-9228	25	19	primates	primate	NOUN
ct-9228	25	20	have	have	AUX
ct-9228	25	21	been	be	AUX
ct-9228	25	22	made14	made14	ADJ
ct-9228	25	23	and	and	CCONJ
ct-9228	25	24	thus	thus	ADV
ct-9228	25	25	it	it	PRON
ct-9228	25	26	is	be	AUX
ct-9228	25	27	theoretically	theoretically	ADV
ct-9228	25	28	possible	possible	ADJ
ct-9228	25	29	,	,	PUNCT
ct-9228	25	30	although	although	SCONJ
ct-9228	25	31	inefficient	inefficient	ADJ
ct-9228	25	32	.	.	PUNCT
ct-9228	26	1	induced	induce	VERB
ct-9228	26	2	pluripotent	pluripotent	ADJ
ct-9228	26	3	stem	stem	NOUN
ct-9228	26	4	cells	cell	NOUN
ct-9228	26	5	induced	induce	VERB
ct-9228	26	6	pluripotent	pluripotent	ADJ
ct-9228	26	7	stem	stem	NOUN
ct-9228	26	8	cells	cell	NOUN
ct-9228	26	9	are	be	AUX
ct-9228	26	10	somatic	somatic	ADJ
ct-9228	26	11	cells	cell	NOUN
ct-9228	26	12	that	that	PRON
ct-9228	26	13	are	be	AUX
ct-9228	26	14	induced	induce	VERB
ct-9228	26	15	,	,	PUNCT
ct-9228	26	16	through	through	ADP
ct-9228	26	17	the	the	DET
ct-9228	26	18	re	re	NOUN
ct-9228	26	19	-	-	NOUN
ct-9228	26	20	expression	expression	NOUN
ct-9228	26	21	of	of	ADP
ct-9228	26	22	developmental	developmental	ADJ
ct-9228	26	23	genes	gene	NOUN
ct-9228	26	24	,	,	PUNCT
ct-9228	26	25	to	to	PART
ct-9228	26	26	become	become	VERB
ct-9228	26	27	pluripotent	pluripotent	ADJ
ct-9228	26	28	.	.	PUNCT
ct-9228	27	1	as	as	ADP
ct-9228	27	2	with	with	ADP
ct-9228	27	3	other	other	ADJ
ct-9228	27	4	types	type	NOUN
ct-9228	27	5	of	of	ADP
ct-9228	27	6	pluripotent	pluripotent	ADJ
ct-9228	27	7	stem	stem	NOUN
ct-9228	27	8	cells	cell	NOUN
ct-9228	27	9	,	,	PUNCT
ct-9228	27	10	this	this	PRON
ct-9228	27	11	was	be	AUX
ct-9228	27	12	first	first	ADV
ct-9228	27	13	achieved	achieve	VERB
ct-9228	27	14	in	in	ADP
ct-9228	27	15	rodent	rodent	ADJ
ct-9228	27	16	cells,15	cells,15	PROPN
ct-9228	27	17	followed	follow	VERB
ct-9228	27	18	by	by	ADP
ct-9228	27	19	other	other	ADJ
ct-9228	27	20	animals	animal	NOUN
ct-9228	27	21	including	include	VERB
ct-9228	27	22	humans.15	humans.15	NOUN
ct-9228	27	23	because	because	SCONJ
ct-9228	27	24	they	they	PRON
ct-9228	27	25	do	do	AUX
ct-9228	27	26	not	not	PART
ct-9228	27	27	require	require	VERB
ct-9228	27	28	the	the	DET
ct-9228	27	29	use	use	NOUN
ct-9228	27	30	of	of	ADP
ct-9228	27	31	an	an	DET
ct-9228	27	32	embryo	embryo	NOUN
ct-9228	27	33	or	or	CCONJ
ct-9228	27	34	oocyte	oocyte	ADJ
ct-9228	27	35	during	during	ADP
ct-9228	27	36	their	their	PRON
ct-9228	27	37	production	production	NOUN
ct-9228	27	38	,	,	PUNCT
ct-9228	27	39	their	their	PRON
ct-9228	27	40	generation	generation	NOUN
ct-9228	27	41	and	and	CCONJ
ct-9228	27	42	use	use	NOUN
ct-9228	27	43	is	be	AUX
ct-9228	27	44	less	less	ADV
ct-9228	27	45	controversial	controversial	ADJ
ct-9228	27	46	than	than	ADP
ct-9228	27	47	other	other	ADJ
ct-9228	27	48	types	type	NOUN
ct-9228	27	49	of	of	ADP
ct-9228	27	50	pluripotent	pluripotent	ADJ
ct-9228	27	51	stem	stem	NOUN
ct-9228	27	52	cells	cell	NOUN
ct-9228	27	53	.	.	PUNCT
ct-9228	28	1	uses	use	NOUN
ct-9228	28	2	of	of	ADP
ct-9228	28	3	pluripotent	pluripotent	ADJ
ct-9228	28	4	stem	stem	NOUN
ct-9228	28	5	cells	cell	NOUN
ct-9228	28	6	pluripotent	pluripotent	ADJ
ct-9228	28	7	stem	stem	NOUN
ct-9228	28	8	cells	cell	NOUN
ct-9228	28	9	are	be	AUX
ct-9228	28	10	used	use	VERB
ct-9228	28	11	for	for	ADP
ct-9228	28	12	many	many	ADJ
ct-9228	28	13	purposes	purpose	NOUN
ct-9228	28	14	,	,	PUNCT
ct-9228	28	15	some	some	PRON
ct-9228	28	16	of	of	ADP
ct-9228	28	17	which	which	PRON
ct-9228	28	18	were	be	AUX
ct-9228	28	19	mentioned	mention	VERB
ct-9228	28	20	above	above	ADV
ct-9228	28	21	.	.	PUNCT
ct-9228	29	1	the	the	DET
ct-9228	29	2	most	most	ADV
ct-9228	29	3	well	well	ADV
ct-9228	29	4	-	-	PUNCT
ct-9228	29	5	known	know	VERB
ct-9228	29	6	uses	use	NOUN
ct-9228	29	7	are	be	AUX
ct-9228	29	8	the	the	DET
ct-9228	29	9	generation	generation	NOUN
ct-9228	29	10	of	of	ADP
ct-9228	29	11	genetically	genetically	ADV
ct-9228	29	12	manipulated	manipulate	VERB
ct-9228	29	13	animals	animal	NOUN
ct-9228	29	14	,	,	PUNCT
ct-9228	29	15	the	the	DET
ct-9228	29	16	production	production	NOUN
ct-9228	29	17	of	of	ADP
ct-9228	29	18	somatic	somatic	ADJ
ct-9228	29	19	cells	cell	NOUN
ct-9228	29	20	for	for	ADP
ct-9228	29	21	transplantation	transplantation	NOUN
ct-9228	29	22	,	,	PUNCT
ct-9228	29	23	and	and	CCONJ
ct-9228	29	24	the	the	DET
ct-9228	29	25	production	production	NOUN
ct-9228	29	26	of	of	ADP
ct-9228	29	27	somatic	somatic	ADJ
ct-9228	29	28	cells	cell	NOUN
ct-9228	29	29	for	for	ADP
ct-9228	29	30	research	research	NOUN
ct-9228	29	31	.	.	PUNCT
ct-9228	30	1	to	to	PART
ct-9228	30	2	generate	generate	VERB
ct-9228	30	3	genetically	genetically	ADV
ct-9228	30	4	manipulated	manipulate	VERB
ct-9228	30	5	animals	animal	NOUN
ct-9228	30	6	,	,	PUNCT
ct-9228	30	7	pluripotent	pluripotent	ADJ
ct-9228	30	8	stem	stem	NOUN
ct-9228	30	9	cells	cell	NOUN
ct-9228	30	10	are	be	AUX
ct-9228	30	11	isolated	isolate	VERB
ct-9228	30	12	from	from	ADP
ct-9228	30	13	embryos	embryo	NOUN
ct-9228	30	14	of	of	ADP
ct-9228	30	15	the	the	DET
ct-9228	30	16	animal	animal	NOUN
ct-9228	30	17	of	of	ADP
ct-9228	30	18	interest	interest	NOUN
ct-9228	30	19	,	,	PUNCT
ct-9228	30	20	e.g.	e.g.	ADV
ct-9228	30	21	a	a	DET
ct-9228	30	22	mouse	mouse	NOUN
ct-9228	30	23	.	.	PUNCT
ct-9228	31	1	those	those	DET
ct-9228	31	2	cells	cell	NOUN
ct-9228	31	3	are	be	AUX
ct-9228	31	4	genetically	genetically	ADV
ct-9228	31	5	manipulated	manipulate	VERB
ct-9228	31	6	,	,	PUNCT
ct-9228	31	7	typically	typically	ADV
ct-9228	31	8	using	use	VERB
ct-9228	31	9	crispr	crispr	ADJ
ct-9228	31	10	/	/	SYM
ct-9228	31	11	cas9	cas9	NOUN
ct-9228	31	12	technology	technology	NOUN
ct-9228	31	13	.	.	PUNCT
ct-9228	32	1	the	the	DET
ct-9228	32	2	manipulated	manipulate	VERB
ct-9228	32	3	cells	cell	NOUN
ct-9228	32	4	can	can	AUX
ct-9228	32	5	then	then	ADV
ct-9228	32	6	be	be	AUX
ct-9228	32	7	injected	inject	VERB
ct-9228	32	8	into	into	ADP
ct-9228	32	9	a	a	DET
ct-9228	32	10	blastocyst	blastocyst	NOUN
ct-9228	32	11	,	,	PUNCT
ct-9228	32	12	which	which	PRON
ct-9228	32	13	results	result	VERB
ct-9228	32	14	in	in	ADP
ct-9228	32	15	the	the	DET
ct-9228	32	16	generation	generation	NOUN
ct-9228	32	17	of	of	ADP
ct-9228	32	18	a	a	DET
ct-9228	32	19	chimeric	chimeric	ADJ
ct-9228	32	20	animal	animal	NOUN
ct-9228	32	21	.	.	PUNCT
ct-9228	33	1	if	if	SCONJ
ct-9228	33	2	any	any	PRON
ct-9228	33	3	of	of	ADP
ct-9228	33	4	the	the	DET
ct-9228	33	5	genetically	genetically	ADV
ct-9228	33	6	altered	alter	VERB
ct-9228	33	7	cells	cell	NOUN
ct-9228	33	8	contribute	contribute	VERB
ct-9228	33	9	to	to	ADP
ct-9228	33	10	the	the	DET
ct-9228	33	11	germline	germline	NOUN
ct-9228	33	12	,	,	PUNCT
ct-9228	33	13	then	then	ADV
ct-9228	33	14	breeding	breed	VERB
ct-9228	33	15	the	the	DET
ct-9228	33	16	animal	animal	NOUN
ct-9228	33	17	results	result	NOUN
ct-9228	33	18	in	in	ADP
ct-9228	33	19	offspring	offspring	NOUN
ct-9228	33	20	that	that	PRON
ct-9228	33	21	are	be	AUX
ct-9228	33	22	genetically	genetically	ADV
ct-9228	33	23	altered.16	altered.16	NOUN
ct-9228	33	24	this	this	PRON
ct-9228	33	25	is	be	AUX
ct-9228	33	26	commonly	commonly	ADV
ct-9228	33	27	used	use	VERB
ct-9228	33	28	to	to	PART
ct-9228	33	29	generate	generate	VERB
ct-9228	33	30	research	research	NOUN
ct-9228	33	31	mice	mouse	NOUN
ct-9228	33	32	to	to	ADP
ct-9228	33	33	model	model	NOUN
ct-9228	33	34	diseases	disease	NOUN
ct-9228	33	35	in	in	ADP
ct-9228	33	36	the	the	DET
ct-9228	33	37	laboratory.16	laboratory.16	PROPN
ct-9228	33	38	one	one	NUM
ct-9228	33	39	of	of	ADP
ct-9228	33	40	the	the	DET
ct-9228	33	41	most	most	ADV
ct-9228	33	42	powerful	powerful	ADJ
ct-9228	33	43	uses	use	NOUN
ct-9228	33	44	of	of	ADP
ct-9228	33	45	pluripotent	pluripotent	ADJ
ct-9228	33	46	stem	stem	NOUN
ct-9228	33	47	cells	cell	NOUN
ct-9228	33	48	is	be	AUX
ct-9228	33	49	the	the	DET
ct-9228	33	50	ability	ability	NOUN
ct-9228	33	51	to	to	PART
ct-9228	33	52	direct	direct	VERB
ct-9228	33	53	differentiation	differentiation	NOUN
ct-9228	33	54	into	into	ADP
ct-9228	33	55	any	any	DET
ct-9228	33	56	cell	cell	NOUN
ct-9228	33	57	type	type	NOUN
ct-9228	33	58	in	in	ADP
ct-9228	33	59	the	the	DET
ct-9228	33	60	body	body	NOUN
ct-9228	33	61	.	.	PUNCT
ct-9228	34	1	in	in	ADP
ct-9228	34	2	this	this	DET
ct-9228	34	3	context	context	NOUN
ct-9228	34	4	,	,	PUNCT
ct-9228	34	5	pluripotent	pluripotent	ADJ
ct-9228	34	6	stem	stem	NOUN
ct-9228	34	7	cells	cell	NOUN
ct-9228	34	8	can	can	AUX
ct-9228	34	9	be	be	AUX
ct-9228	34	10	expanded	expand	VERB
ct-9228	34	11	into	into	ADP
ct-9228	34	12	large	large	ADJ
ct-9228	34	13	batches	batch	NOUN
ct-9228	34	14	and	and	CCONJ
ct-9228	34	15	differentiated	differentiate	VERB
ct-9228	34	16	into	into	ADP
ct-9228	34	17	the	the	DET
ct-9228	34	18	cell	cell	NOUN
ct-9228	34	19	type	type	NOUN
ct-9228	34	20	of	of	ADP
ct-9228	34	21	interest	interest	NOUN
ct-9228	34	22	,	,	PUNCT
ct-9228	34	23	which	which	PRON
ct-9228	34	24	is	be	AUX
ct-9228	34	25	then	then	ADV
ct-9228	34	26	used	use	VERB
ct-9228	34	27	for	for	ADP
ct-9228	34	28	research	research	NOUN
ct-9228	34	29	purposes	purpose	NOUN
ct-9228	34	30	.	.	PUNCT
ct-9228	35	1	this	this	DET
ct-9228	35	2	strategy	strategy	NOUN
ct-9228	35	3	is	be	AUX
ct-9228	35	4	particularly	particularly	ADV
ct-9228	35	5	important	important	ADJ
ct-9228	35	6	for	for	ADP
ct-9228	35	7	cells	cell	NOUN
ct-9228	35	8	that	that	PRON
ct-9228	35	9	are	be	AUX
ct-9228	35	10	postmitotic	postmitotic	ADJ
ct-9228	35	11	in	in	ADP
ct-9228	35	12	adults	adult	NOUN
ct-9228	35	13	,	,	PUNCT
ct-9228	35	14	such	such	ADJ
ct-9228	35	15	as	as	ADP
ct-9228	35	16	neurons	neuron	NOUN
ct-9228	35	17	.	.	PUNCT
ct-9228	36	1	proliferative	proliferative	ADJ
ct-9228	36	2	cells	cell	NOUN
ct-9228	36	3	can	can	AUX
ct-9228	36	4	be	be	AUX
ct-9228	36	5	obtained	obtain	VERB
ct-9228	36	6	from	from	ADP
ct-9228	36	7	a	a	DET
ct-9228	36	8	patient	patient	NOUN
ct-9228	36	9	,	,	PUNCT
ct-9228	36	10	grown	grow	VERB
ct-9228	36	11	in	in	ADP
ct-9228	36	12	culture	culture	NOUN
ct-9228	36	13	,	,	PUNCT
ct-9228	36	14	and	and	CCONJ
ct-9228	36	15	investigated	investigate	VERB
ct-9228	36	16	;	;	PUNCT
ct-9228	36	17	however	however	ADV
ct-9228	36	18	,	,	PUNCT
ct-9228	36	19	if	if	SCONJ
ct-9228	36	20	the	the	DET
ct-9228	36	21	cell	cell	NOUN
ct-9228	36	22	type	type	NOUN
ct-9228	36	23	of	of	ADP
ct-9228	36	24	interest	interest	NOUN
ct-9228	36	25	in	in	ADP
ct-9228	36	26	the	the	DET
ct-9228	36	27	disease	disease	NOUN
ct-9228	36	28	is	be	AUX
ct-9228	36	29	postmitotic	postmitotic	ADJ
ct-9228	36	30	,	,	PUNCT
ct-9228	36	31	obtaining	obtain	VERB
ct-9228	36	32	a	a	DET
ct-9228	36	33	sufficient	sufficient	ADJ
ct-9228	36	34	quantity	quantity	NOUN
ct-9228	36	35	of	of	ADP
ct-9228	36	36	cells	cell	NOUN
ct-9228	36	37	for	for	ADP
ct-9228	36	38	experimental	experimental	ADJ
ct-9228	36	39	use	use	NOUN
ct-9228	36	40	is	be	AUX
ct-9228	36	41	impossible	impossible	ADJ
ct-9228	36	42	.	.	PUNCT
ct-9228	37	1	examples	example	NOUN
ct-9228	37	2	include	include	VERB
ct-9228	37	3	neurodegenerative	neurodegenerative	ADJ
ct-9228	37	4	diseases	disease	NOUN
ct-9228	37	5	such	such	ADJ
ct-9228	37	6	as	as	ADP
ct-9228	37	7	alzheimer	alzheimer	PROPN
ct-9228	37	8	’s	’s	PART
ct-9228	37	9	disease	disease	NOUN
ct-9228	37	10	or	or	CCONJ
ct-9228	37	11	amyotrophic	amyotrophic	ADJ
ct-9228	37	12	lateral	lateral	ADJ
ct-9228	37	13	sclerosis	sclerosis	NOUN
ct-9228	37	14	(	(	PUNCT
ct-9228	37	15	als	als	NOUN
ct-9228	37	16	)	)	PUNCT
ct-9228	37	17	,	,	PUNCT
ct-9228	37	18	where	where	SCONJ
ct-9228	37	19	the	the	DET
ct-9228	37	20	cell	cell	NOUN
ct-9228	37	21	type	type	NOUN
ct-9228	37	22	of	of	ADP
ct-9228	37	23	interest	interest	NOUN
ct-9228	37	24	is	be	AUX
ct-9228	37	25	the	the	DET
ct-9228	37	26	neuron	neuron	PROPN
ct-9228	37	27	.	.	PUNCT
ct-9228	38	1	live	live	VERB
ct-9228	38	2	human	human	ADJ
ct-9228	38	3	neurons	neuron	NOUN
ct-9228	38	4	generally	generally	ADV
ct-9228	38	5	can	can	AUX
ct-9228	38	6	not	not	PART
ct-9228	38	7	be	be	AUX
ct-9228	38	8	studied	study	VERB
ct-9228	38	9	,	,	PUNCT
ct-9228	38	10	except	except	SCONJ
ct-9228	38	11	through	through	ADP
ct-9228	38	12	the	the	DET
ct-9228	38	13	generation	generation	NOUN
ct-9228	38	14	of	of	ADP
ct-9228	38	15	neurons	neuron	NOUN
ct-9228	38	16	from	from	ADP
ct-9228	38	17	pluripotent	pluripotent	ADJ
ct-9228	38	18	stem	stem	NOUN
ct-9228	38	19	cells	cell	NOUN
ct-9228	38	20	.	.	PUNCT
ct-9228	39	1	research	research	NOUN
ct-9228	39	2	in	in	ADP
ct-9228	39	3	human	human	ADJ
ct-9228	39	4	neuroscience	neuroscience	NOUN
ct-9228	39	5	has	have	AUX
ct-9228	39	6	accelerated	accelerate	VERB
ct-9228	39	7	exponentially	exponentially	ADV
ct-9228	39	8	since	since	SCONJ
ct-9228	39	9	human	human	ADJ
ct-9228	39	10	pluripotent	pluripotent	NOUN
ct-9228	39	11	stem	stem	NOUN
ct-9228	39	12	cells	cell	NOUN
ct-9228	39	13	were	be	AUX
ct-9228	39	14	discovered	discover	VERB
ct-9228	39	15	.	.	PUNCT
ct-9228	40	1	the	the	DET
ct-9228	40	2	same	same	ADJ
ct-9228	40	3	directed	direct	VERB
ct-9228	40	4	differentiation	differentiation	NOUN
ct-9228	40	5	procedure	procedure	NOUN
ct-9228	40	6	can	can	AUX
ct-9228	40	7	be	be	AUX
ct-9228	40	8	used	use	VERB
ct-9228	40	9	to	to	PART
ct-9228	40	10	generate	generate	VERB
ct-9228	40	11	somatic	somatic	ADJ
ct-9228	40	12	cells	cell	NOUN
ct-9228	40	13	for	for	ADP
ct-9228	40	14	transplantation	transplantation	NOUN
ct-9228	40	15	,	,	PUNCT
ct-9228	40	16	with	with	ADP
ct-9228	40	17	the	the	DET
ct-9228	40	18	caveat	caveat	NOUN
ct-9228	40	19	that	that	SCONJ
ct-9228	40	20	the	the	DET
ct-9228	40	21	pluripotent	pluripotent	ADJ
ct-9228	40	22	stem	stem	NOUN
ct-9228	40	23	cell	cell	NOUN
ct-9228	40	24	generation	generation	NOUN
ct-9228	40	25	,	,	PUNCT
ct-9228	40	26	growth	growth	NOUN
ct-9228	40	27	,	,	PUNCT
ct-9228	40	28	and	and	CCONJ
ct-9228	40	29	subsequent	subsequent	ADJ
ct-9228	40	30	differentiation	differentiation	NOUN
ct-9228	40	31	are	be	AUX
ct-9228	40	32	done	do	VERB
ct-9228	40	33	under	under	ADP
ct-9228	40	34	general	general	ADJ
ct-9228	40	35	manufacturing	manufacturing	NOUN
ct-9228	40	36	procedure	procedure	NOUN
ct-9228	40	37	conditions	condition	NOUN
ct-9228	40	38	,	,	PUNCT
ct-9228	40	39	which	which	PRON
ct-9228	40	40	are	be	AUX
ct-9228	40	41	the	the	DET
ct-9228	40	42	practices	practice	NOUN
ct-9228	40	43	required	require	VERB
ct-9228	40	44	to	to	PART
ct-9228	40	45	make	make	VERB
ct-9228	40	46	clinical	clinical	ADJ
ct-9228	40	47	grade	grade	NOUN
ct-9228	40	48	products	product	NOUN
ct-9228	40	49	.	.	PUNCT
ct-9228	41	1	however	however	ADV
ct-9228	41	2	,	,	PUNCT
ct-9228	41	3	a	a	DET
ct-9228	41	4	significant	significant	ADJ
ct-9228	41	5	caveat	caveat	NOUN
ct-9228	41	6	to	to	ADP
ct-9228	41	7	the	the	DET
ct-9228	41	8	translation	translation	NOUN
ct-9228	41	9	of	of	ADP
ct-9228	41	10	this	this	DET
ct-9228	41	11	technology	technology	NOUN
ct-9228	41	12	to	to	ADP
ct-9228	41	13	the	the	DET
ct-9228	41	14	clinic	clinic	NOUN
ct-9228	41	15	is	be	AUX
ct-9228	41	16	that	that	SCONJ
ct-9228	41	17	it	it	PRON
ct-9228	41	18	is	be	AUX
ct-9228	41	19	extremely	extremely	ADV
ct-9228	41	20	difficult	difficult	ADJ
ct-9228	41	21	to	to	PART
ct-9228	41	22	ensure	ensure	VERB
ct-9228	41	23	that	that	SCONJ
ct-9228	41	24	differentiation	differentiation	NOUN
ct-9228	41	25	efficiency	efficiency	NOUN
ct-9228	41	26	is	be	AUX
ct-9228	41	27	100	100	NUM
ct-9228	41	28	%	%	NOUN
ct-9228	41	29	before	before	ADP
ct-9228	41	30	transplantation	transplantation	NOUN
ct-9228	41	31	.	.	PUNCT
ct-9228	42	1	less	less	ADJ
ct-9228	42	2	than	than	ADP
ct-9228	42	3	perfect	perfect	ADJ
ct-9228	42	4	efficiency	efficiency	NOUN
ct-9228	42	5	could	could	AUX
ct-9228	42	6	result	result	VERB
ct-9228	42	7	in	in	ADP
ct-9228	42	8	the	the	DET
ct-9228	42	9	transfer	transfer	NOUN
ct-9228	42	10	of	of	ADP
ct-9228	42	11	undifferentiated	undifferentiated	ADJ
ct-9228	42	12	cells	cell	NOUN
ct-9228	42	13	that	that	PRON
ct-9228	42	14	result	result	VERB
ct-9228	42	15	in	in	ADP
ct-9228	42	16	teratoma	teratoma	ADJ
ct-9228	42	17	formation	formation	NOUN
ct-9228	42	18	in	in	ADP
ct-9228	42	19	the	the	DET
ct-9228	42	20	patient	patient	NOUN
ct-9228	42	21	.	.	PUNCT
ct-9228	43	1	pluripotent	pluripotent	ADJ
ct-9228	43	2	stem	stem	NOUN
ct-9228	43	3	cell	cell	NOUN
ct-9228	43	4	characteristics	characteristic	NOUN
ct-9228	43	5	pluripotent	pluripotent	ADJ
ct-9228	43	6	stem	stem	NOUN
ct-9228	43	7	cells	cell	NOUN
ct-9228	43	8	have	have	VERB
ct-9228	43	9	incredible	incredible	ADJ
ct-9228	43	10	potential	potential	NOUN
ct-9228	43	11	,	,	PUNCT
ct-9228	43	12	but	but	CCONJ
ct-9228	43	13	they	they	PRON
ct-9228	43	14	are	be	AUX
ct-9228	43	15	not	not	PART
ct-9228	43	16	easy	easy	ADJ
ct-9228	43	17	to	to	PART
ct-9228	43	18	work	work	VERB
ct-9228	43	19	with	with	ADP
ct-9228	43	20	,	,	PUNCT
ct-9228	43	21	for	for	ADP
ct-9228	43	22	several	several	ADJ
ct-9228	43	23	reasons	reason	NOUN
ct-9228	43	24	.	.	PUNCT
ct-9228	44	1	they	they	PRON
ct-9228	44	2	require	require	VERB
ct-9228	44	3	a	a	DET
ct-9228	44	4	full	full	ADJ
ct-9228	44	5	knowledge	knowledge	NOUN
ct-9228	44	6	of	of	ADP
ct-9228	44	7	the	the	DET
ct-9228	44	8	starting	starting	NOUN
ct-9228	44	9	cell	cell	NOUN
ct-9228	44	10	source	source	NOUN
ct-9228	44	11	and	and	CCONJ
ct-9228	44	12	ongoing	ongoing	ADJ
ct-9228	44	13	quality	quality	NOUN
ct-9228	44	14	control	control	NOUN
ct-9228	44	15	to	to	PART
ct-9228	44	16	be	be	AUX
ct-9228	44	17	sure	sure	ADJ
ct-9228	44	18	that	that	SCONJ
ct-9228	44	19	they	they	PRON
ct-9228	44	20	are	be	AUX
ct-9228	44	21	and	and	CCONJ
ct-9228	44	22	remain	remain	VERB
ct-9228	44	23	pluripotent	pluripotent	ADJ
ct-9228	44	24	.	.	PUNCT
ct-9228	45	1	until	until	ADP
ct-9228	45	2	this	this	DET
ct-9228	45	3	point	point	NOUN
ct-9228	45	4	,	,	PUNCT
ct-9228	45	5	all	all	DET
ct-9228	45	6	the	the	DET
ct-9228	45	7	information	information	NOUN
ct-9228	45	8	above	above	ADV
ct-9228	45	9	has	have	AUX
ct-9228	45	10	applied	apply	VERB
ct-9228	45	11	to	to	ADP
ct-9228	45	12	pluripotent	pluripotent	ADJ
ct-9228	45	13	stem	stem	NOUN
ct-9228	45	14	cells	cell	NOUN
ct-9228	45	15	from	from	ADP
ct-9228	45	16	any	any	DET
ct-9228	45	17	source	source	NOUN
ct-9228	45	18	.	.	PUNCT
ct-9228	46	1	this	this	PRON
ct-9228	46	2	implies	imply	VERB
ct-9228	46	3	that	that	SCONJ
ct-9228	46	4	embryonic	embryonic	ADJ
ct-9228	46	5	stem	stem	NOUN
ct-9228	46	6	cells	cell	NOUN
ct-9228	46	7	,	,	PUNCT
ct-9228	46	8	somatic	somatic	ADJ
ct-9228	46	9	cell	cell	NOUN
ct-9228	46	10	nuclear	nuclear	ADJ
ct-9228	46	11	transfer	transfer	NOUN
ct-9228	46	12	cells	cell	NOUN
ct-9228	46	13	,	,	PUNCT
ct-9228	46	14	and	and	CCONJ
ct-9228	46	15	induced	induce	VERB
ct-9228	46	16	pluripotent	pluripotent	ADJ
ct-9228	46	17	stem	stem	NOUN
ct-9228	46	18	cells	cell	NOUN
ct-9228	46	19	are	be	AUX
ct-9228	46	20	equivalent	equivalent	ADJ
ct-9228	46	21	.	.	PUNCT
ct-9228	47	1	however	however	ADV
ct-9228	47	2	,	,	PUNCT
ct-9228	47	3	there	there	PRON
ct-9228	47	4	are	be	VERB
ct-9228	47	5	data	datum	NOUN
ct-9228	47	6	demonstrating	demonstrate	VERB
ct-9228	47	7	that	that	SCONJ
ct-9228	47	8	this	this	PRON
ct-9228	47	9	is	be	AUX
ct-9228	47	10	not	not	PART
ct-9228	47	11	true	true	ADJ
ct-9228	47	12	.	.	PUNCT
ct-9228	48	1	when	when	SCONJ
ct-9228	48	2	embryonic	embryonic	ADJ
ct-9228	48	3	stem	stem	NOUN
ct-9228	48	4	cells	cell	NOUN
ct-9228	48	5	,	,	PUNCT
ct-9228	48	6	somatic	somatic	ADJ
ct-9228	48	7	cell	cell	NOUN
ct-9228	48	8	transfer	transfer	NOUN
ct-9228	48	9	stem	stem	NOUN
ct-9228	48	10	cells	cell	NOUN
ct-9228	48	11	,	,	PUNCT
ct-9228	48	12	and	and	CCONJ
ct-9228	48	13	induced	induce	VERB
ct-9228	48	14	pluripotent	pluripotent	ADJ
ct-9228	48	15	stem	stem	NOUN
ct-9228	48	16	cells	cell	NOUN
ct-9228	48	17	are	be	AUX
ct-9228	48	18	examined	examine	VERB
ct-9228	48	19	side	side	NOUN
ct-9228	48	20	-	-	PUNCT
ct-9228	48	21	by	by	ADP
ct-9228	48	22	-	-	PUNCT
ct-9228	48	23	side	side	NOUN
ct-9228	48	24	,	,	PUNCT
ct-9228	48	25	there	there	PRON
ct-9228	48	26	are	be	VERB
ct-9228	48	27	phenotypic	phenotypic	ADJ
ct-9228	48	28	differences	difference	NOUN
ct-9228	48	29	among	among	ADP
ct-9228	48	30	them	they	PRON
ct-9228	48	31	.	.	PUNCT
ct-9228	49	1	although	although	SCONJ
ct-9228	49	2	the	the	DET
ct-9228	49	3	exact	exact	ADJ
ct-9228	49	4	consequences	consequence	NOUN
ct-9228	49	5	of	of	ADP
ct-9228	49	6	these	these	DET
ct-9228	49	7	differences	difference	NOUN
ct-9228	49	8	are	be	AUX
ct-9228	49	9	unclear	unclear	ADJ
ct-9228	49	10	,	,	PUNCT
ct-9228	49	11	we	we	PRON
ct-9228	49	12	can	can	AUX
ct-9228	49	13	not	not	PART
ct-9228	49	14	assume	assume	VERB
ct-9228	49	15	that	that	SCONJ
ct-9228	49	16	all	all	DET
ct-9228	49	17	sources	source	NOUN
ct-9228	49	18	of	of	ADP
ct-9228	49	19	pluripotent	pluripotent	ADJ
ct-9228	49	20	cells	cell	NOUN
ct-9228	49	21	will	will	AUX
ct-9228	49	22	perform	perform	VERB
ct-9228	49	23	equivalently	equivalently	ADV
ct-9228	49	24	in	in	ADP
ct-9228	49	25	the	the	DET
ct-9228	49	26	generation	generation	NOUN
ct-9228	49	27	of	of	ADP
ct-9228	49	28	somatic	somatic	ADJ
ct-9228	49	29	cells	cell	NOUN
ct-9228	49	30	,	,	PUNCT
ct-9228	49	31	regardless	regardless	ADV
ct-9228	49	32	of	of	ADP
ct-9228	49	33	whether	whether	SCONJ
ct-9228	49	34	the	the	DET
ct-9228	49	35	final	final	ADJ
ct-9228	49	36	use	use	NOUN
ct-9228	49	37	is	be	AUX
ct-9228	49	38	research	research	NOUN
ct-9228	49	39	or	or	CCONJ
ct-9228	49	40	transplantation	transplantation	NOUN
ct-9228	49	41	.	.	PUNCT
ct-9228	50	1	a	a	DET
ct-9228	50	2	key	key	ADJ
ct-9228	50	3	point	point	NOUN
ct-9228	50	4	that	that	PRON
ct-9228	50	5	needs	need	VERB
ct-9228	50	6	to	to	PART
ct-9228	50	7	be	be	AUX
ct-9228	50	8	satisfied	satisfied	ADJ
ct-9228	50	9	before	before	ADP
ct-9228	50	10	using	use	VERB
ct-9228	50	11	any	any	DET
ct-9228	50	12	pluripotent	pluripotent	ADJ
ct-9228	50	13	stem	stem	NOUN
ct-9228	50	14	cell	cell	NOUN
ct-9228	50	15	is	be	AUX
ct-9228	50	16	to	to	PART
ct-9228	50	17	ensure	ensure	VERB
ct-9228	50	18	that	that	SCONJ
ct-9228	50	19	it	it	PRON
ct-9228	50	20	is	be	AUX
ct-9228	50	21	truly	truly	ADV
ct-9228	50	22	pluripotent	pluripotent	ADJ
ct-9228	50	23	.	.	PUNCT
ct-9228	51	1	there	there	PRON
ct-9228	51	2	are	be	VERB
ct-9228	51	3	several	several	ADJ
ct-9228	51	4	levels	level	NOUN
ct-9228	51	5	of	of	ADP
ct-9228	51	6	stringency	stringency	NOUN
ct-9228	51	7	that	that	PRON
ct-9228	51	8	need	need	VERB
ct-9228	51	9	to	to	PART
ct-9228	51	10	be	be	AUX
ct-9228	51	11	met	meet	VERB
ct-9228	51	12	to	to	PART
ct-9228	51	13	prove	prove	VERB
ct-9228	51	14	pluripotency.18	pluripotency.18	VERB
ct-9228	51	15	the	the	DET
ct-9228	51	16	clinical	clinical	ADJ
ct-9228	51	17	theriogenology	theriogenology	NOUN
ct-9228	52	1	•	•	NOUN
ct-9228	52	2	volume	volume	NOUN
ct-9228	52	3	12	12	NUM
ct-9228	52	4	number	number	NOUN
ct-9228	52	5	3	3	NUM
ct-9228	52	6	•	•	NOUN
ct-9228	52	7	september	september	PROPN
ct-9228	52	8	2020184	2020184	NUM
ct-9228	52	9	easiest	easy	ADJ
ct-9228	52	10	is	be	AUX
ct-9228	52	11	to	to	PART
ct-9228	52	12	look	look	VERB
ct-9228	52	13	at	at	ADP
ct-9228	52	14	molecular	molecular	ADJ
ct-9228	52	15	criteria	criterion	NOUN
ct-9228	52	16	.	.	PUNCT
ct-9228	53	1	for	for	ADP
ct-9228	53	2	example	example	NOUN
ct-9228	53	3	,	,	PUNCT
ct-9228	53	4	cells	cell	NOUN
ct-9228	53	5	can	can	AUX
ct-9228	53	6	be	be	AUX
ct-9228	53	7	analyzed	analyze	VERB
ct-9228	53	8	for	for	ADP
ct-9228	53	9	the	the	DET
ct-9228	53	10	expression	expression	NOUN
ct-9228	53	11	of	of	ADP
ct-9228	53	12	pluripotent	pluripotent	ADJ
ct-9228	53	13	genes	gene	NOUN
ct-9228	53	14	and	and	CCONJ
ct-9228	53	15	the	the	DET
ct-9228	53	16	absence	absence	NOUN
ct-9228	53	17	of	of	ADP
ct-9228	53	18	expression	expression	NOUN
ct-9228	53	19	of	of	ADP
ct-9228	53	20	somatic	somatic	ADJ
ct-9228	53	21	genes.19	genes.19	NOUN
ct-9228	53	22	similar	similar	ADJ
ct-9228	53	23	protein	protein	NOUN
ct-9228	53	24	profiles	profile	NOUN
ct-9228	53	25	can	can	AUX
ct-9228	53	26	also	also	ADV
ct-9228	53	27	be	be	AUX
ct-9228	53	28	examined.19	examined.19	NOUN
ct-9228	53	29	however	however	ADV
ct-9228	53	30	,	,	PUNCT
ct-9228	53	31	molecular	molecular	ADJ
ct-9228	53	32	markers	marker	NOUN
ct-9228	53	33	are	be	AUX
ct-9228	53	34	not	not	PART
ct-9228	53	35	perfect	perfect	ADJ
ct-9228	53	36	and	and	CCONJ
ct-9228	53	37	analysis	analysis	NOUN
ct-9228	53	38	of	of	ADP
ct-9228	53	39	pluripotent	pluripotent	ADJ
ct-9228	53	40	functionality	functionality	NOUN
ct-9228	53	41	is	be	AUX
ct-9228	53	42	always	always	ADV
ct-9228	53	43	preferred	prefer	VERB
ct-9228	53	44	.	.	PUNCT
ct-9228	54	1	more	more	ADV
ct-9228	54	2	rigorous	rigorous	ADJ
ct-9228	54	3	is	be	AUX
ct-9228	54	4	to	to	PART
ct-9228	54	5	look	look	VERB
ct-9228	54	6	at	at	ADP
ct-9228	54	7	the	the	DET
ct-9228	54	8	ability	ability	NOUN
ct-9228	54	9	to	to	PART
ct-9228	54	10	differentiate	differentiate	VERB
ct-9228	54	11	into	into	ADP
ct-9228	54	12	all	all	DET
ct-9228	54	13	3	3	NUM
ct-9228	54	14	germ	germ	NOUN
ct-9228	54	15	layers	layer	NOUN
ct-9228	54	16	using	use	VERB
ct-9228	54	17	in	in	ADP
ct-9228	54	18	vitro	vitro	X
ct-9228	54	19	differentiation	differentiation	NOUN
ct-9228	54	20	protocols.18	protocols.18	NOUN
ct-9228	54	21	the	the	DET
ct-9228	54	22	most	most	ADV
ct-9228	54	23	rigorous	rigorous	ADJ
ct-9228	54	24	method	method	NOUN
ct-9228	54	25	is	be	AUX
ct-9228	54	26	to	to	PART
ct-9228	54	27	truly	truly	ADV
ct-9228	54	28	test	test	VERB
ct-9228	54	29	pluripotentiality	pluripotentiality	NOUN
ct-9228	54	30	by	by	ADP
ct-9228	54	31	producing	produce	VERB
ct-9228	54	32	chimeric	chimeric	ADJ
ct-9228	54	33	animals	animal	NOUN
ct-9228	54	34	and	and	CCONJ
ct-9228	54	35	demonstrating	demonstrate	VERB
ct-9228	54	36	that	that	SCONJ
ct-9228	54	37	the	the	DET
ct-9228	54	38	pluripotent	pluripotent	ADJ
ct-9228	54	39	stem	stem	NOUN
ct-9228	54	40	cell	cell	NOUN
ct-9228	54	41	contributed	contribute	VERB
ct-9228	54	42	to	to	ADP
ct-9228	54	43	each	each	DET
ct-9228	54	44	germ	germ	NOUN
ct-9228	54	45	layer	layer	NOUN
ct-9228	54	46	plus	plus	CCONJ
ct-9228	54	47	germ	germ	NOUN
ct-9228	54	48	cells.2	cells.2	NOUN
ct-9228	54	49	immortality	immortality	NOUN
ct-9228	54	50	is	be	AUX
ct-9228	54	51	a	a	DET
ct-9228	54	52	key	key	ADJ
ct-9228	54	53	characteristic	characteristic	NOUN
ct-9228	54	54	of	of	ADP
ct-9228	54	55	pluripotent	pluripotent	ADJ
ct-9228	54	56	stem	stem	NOUN
ct-9228	54	57	cells	cell	NOUN
ct-9228	54	58	;	;	PUNCT
ct-9228	54	59	however	however	ADV
ct-9228	54	60	,	,	PUNCT
ct-9228	54	61	this	this	PRON
ct-9228	54	62	does	do	AUX
ct-9228	54	63	not	not	PART
ct-9228	54	64	imply	imply	VERB
ct-9228	54	65	stability	stability	NOUN
ct-9228	54	66	in	in	ADP
ct-9228	54	67	culture	culture	NOUN
ct-9228	54	68	.	.	PUNCT
ct-9228	55	1	in	in	ADP
ct-9228	55	2	fact	fact	NOUN
ct-9228	55	3	,	,	PUNCT
ct-9228	55	4	karyotypic	karyotypic	NOUN
ct-9228	55	5	instability	instability	NOUN
ct-9228	55	6	was	be	AUX
ct-9228	55	7	recognized	recognize	VERB
ct-9228	55	8	as	as	ADP
ct-9228	55	9	a	a	DET
ct-9228	55	10	concern	concern	NOUN
ct-9228	55	11	early	early	ADV
ct-9228	55	12	in	in	ADP
ct-9228	55	13	the	the	DET
ct-9228	55	14	use	use	NOUN
ct-9228	55	15	of	of	ADP
ct-9228	55	16	the	the	DET
ct-9228	55	17	cells.20	cells.20	NOUN
ct-9228	55	18	improved	improve	VERB
ct-9228	55	19	culture	culture	NOUN
ct-9228	55	20	methods	method	NOUN
ct-9228	55	21	have	have	AUX
ct-9228	55	22	decreased	decrease	VERB
ct-9228	55	23	the	the	DET
ct-9228	55	24	occurrence	occurrence	NOUN
ct-9228	55	25	of	of	ADP
ct-9228	55	26	large	large	ADJ
ct-9228	55	27	chromosomal	chromosomal	ADJ
ct-9228	55	28	aberrations	aberration	NOUN
ct-9228	55	29	,	,	PUNCT
ct-9228	55	30	but	but	CCONJ
ct-9228	55	31	careful	careful	ADJ
ct-9228	55	32	analysis	analysis	NOUN
ct-9228	55	33	demonstrates	demonstrate	VERB
ct-9228	55	34	that	that	SCONJ
ct-9228	55	35	with	with	ADP
ct-9228	55	36	passage	passage	NOUN
ct-9228	55	37	,	,	PUNCT
ct-9228	55	38	pluripotent	pluripotent	ADJ
ct-9228	55	39	stem	stem	NOUN
ct-9228	55	40	cell	cell	NOUN
ct-9228	55	41	lines	line	NOUN
ct-9228	55	42	change	change	VERB
ct-9228	55	43	over	over	ADP
ct-9228	55	44	time	time	NOUN
ct-9228	55	45	,	,	PUNCT
ct-9228	55	46	with	with	ADP
ct-9228	55	47	numerous	numerous	ADJ
ct-9228	55	48	chromosomal	chromosomal	ADJ
ct-9228	55	49	differences	difference	NOUN
ct-9228	55	50	,	,	PUNCT
ct-9228	55	51	most	most	ADV
ct-9228	55	52	less	less	ADJ
ct-9228	55	53	than	than	ADP
ct-9228	55	54	100	100	NUM
ct-9228	55	55	kilobases	kilobase	NOUN
ct-9228	55	56	of	of	ADP
ct-9228	55	57	dna	dna	NOUN
ct-9228	55	58	in	in	ADP
ct-9228	55	59	size.21	size.21	PROPN
ct-9228	55	60	furthermore	furthermore	ADV
ct-9228	55	61	,	,	PUNCT
ct-9228	55	62	these	these	DET
ct-9228	55	63	changes	change	NOUN
ct-9228	55	64	can	can	AUX
ct-9228	55	65	alter	alter	VERB
ct-9228	55	66	the	the	DET
ct-9228	55	67	ability	ability	NOUN
ct-9228	55	68	to	to	PART
ct-9228	55	69	differentiate	differentiate	VERB
ct-9228	55	70	into	into	ADP
ct-9228	55	71	certain	certain	ADJ
ct-9228	55	72	somatic	somatic	ADJ
ct-9228	55	73	cell	cell	NOUN
ct-9228	55	74	types.21	types.21	NOUN
ct-9228	55	75	thus	thus	ADV
ct-9228	55	76	,	,	PUNCT
ct-9228	55	77	careful	careful	ADJ
ct-9228	55	78	and	and	CCONJ
ct-9228	55	79	constant	constant	ADJ
ct-9228	55	80	quality	quality	NOUN
ct-9228	55	81	control	control	NOUN
ct-9228	55	82	of	of	ADP
ct-9228	55	83	pluripotent	pluripotent	ADJ
ct-9228	55	84	stem	stem	NOUN
ct-9228	55	85	cells	cell	NOUN
ct-9228	55	86	is	be	AUX
ct-9228	55	87	required	require	VERB
ct-9228	55	88	.	.	PUNCT
ct-9228	56	1	advantages	advantage	NOUN
ct-9228	56	2	and	and	CCONJ
ct-9228	56	3	disadvantages	disadvantage	NOUN
ct-9228	56	4	in	in	ADP
ct-9228	56	5	summary	summary	NOUN
ct-9228	56	6	,	,	PUNCT
ct-9228	56	7	pluripotent	pluripotent	ADJ
ct-9228	56	8	stem	stem	NOUN
ct-9228	56	9	cells	cell	NOUN
ct-9228	56	10	are	be	AUX
ct-9228	56	11	a	a	DET
ct-9228	56	12	powerful	powerful	ADJ
ct-9228	56	13	tool	tool	NOUN
ct-9228	56	14	for	for	ADP
ct-9228	56	15	medicine	medicine	NOUN
ct-9228	56	16	and	and	CCONJ
ct-9228	56	17	research	research	NOUN
ct-9228	56	18	.	.	PUNCT
ct-9228	57	1	their	their	PRON
ct-9228	57	2	potency	potency	NOUN
ct-9228	57	3	can	can	AUX
ct-9228	57	4	be	be	AUX
ct-9228	57	5	harnessed	harness	VERB
ct-9228	57	6	to	to	PART
ct-9228	57	7	generate	generate	VERB
ct-9228	57	8	somatic	somatic	ADJ
ct-9228	57	9	cells	cell	NOUN
ct-9228	57	10	for	for	ADP
ct-9228	57	11	research	research	NOUN
ct-9228	57	12	and	and	CCONJ
ct-9228	57	13	for	for	ADP
ct-9228	57	14	the	the	DET
ct-9228	57	15	clinic	clinic	NOUN
ct-9228	57	16	,	,	PUNCT
ct-9228	57	17	as	as	ADV
ct-9228	57	18	well	well	ADV
ct-9228	57	19	as	as	ADP
ct-9228	57	20	to	to	PART
ct-9228	57	21	advance	advance	VERB
ct-9228	57	22	our	our	PRON
ct-9228	57	23	understanding	understanding	NOUN
ct-9228	57	24	of	of	ADP
ct-9228	57	25	developmental	developmental	ADJ
ct-9228	57	26	biology	biology	NOUN
ct-9228	57	27	.	.	PUNCT
ct-9228	58	1	however	however	ADV
ct-9228	58	2	,	,	PUNCT
ct-9228	58	3	they	they	PRON
ct-9228	58	4	have	have	VERB
ct-9228	58	5	some	some	DET
ct-9228	58	6	key	key	ADJ
ct-9228	58	7	disadvantages	disadvantage	NOUN
ct-9228	58	8	.	.	PUNCT
ct-9228	59	1	most	most	ADV
ct-9228	59	2	importantly	importantly	ADV
ct-9228	59	3	,	,	PUNCT
ct-9228	59	4	anything	anything	PRON
ct-9228	59	5	less	less	ADJ
ct-9228	59	6	than	than	ADP
ct-9228	59	7	completely	completely	ADV
ct-9228	59	8	efficient	efficient	ADJ
ct-9228	59	9	differentiation	differentiation	NOUN
ct-9228	59	10	could	could	AUX
ct-9228	59	11	result	result	VERB
ct-9228	59	12	in	in	ADP
ct-9228	59	13	development	development	NOUN
ct-9228	59	14	of	of	ADP
ct-9228	59	15	subsequent	subsequent	ADJ
ct-9228	59	16	cancer	cancer	NOUN
ct-9228	59	17	in	in	ADP
ct-9228	59	18	a	a	DET
ct-9228	59	19	patient	patient	NOUN
ct-9228	59	20	after	after	ADP
ct-9228	59	21	transplantation.22	transplantation.22	NOUN
ct-9228	59	22	other	other	ADJ
ct-9228	59	23	disadvantages	disadvantage	NOUN
ct-9228	59	24	for	for	ADP
ct-9228	59	25	clinical	clinical	ADJ
ct-9228	59	26	use	use	NOUN
ct-9228	59	27	include	include	VERB
ct-9228	59	28	that	that	SCONJ
ct-9228	59	29	differentiated	differentiated	ADJ
ct-9228	59	30	pluripotent	pluripotent	ADJ
ct-9228	59	31	stem	stem	NOUN
ct-9228	59	32	cells	cell	NOUN
ct-9228	59	33	for	for	ADP
ct-9228	59	34	transplantation	transplantation	NOUN
ct-9228	59	35	are	be	AUX
ct-9228	59	36	not	not	PART
ct-9228	59	37	immune	immune	ADJ
ct-9228	59	38	matched	match	VERB
ct-9228	59	39	to	to	ADP
ct-9228	59	40	recipients	recipient	NOUN
ct-9228	59	41	and	and	CCONJ
ct-9228	59	42	would	would	AUX
ct-9228	59	43	be	be	AUX
ct-9228	59	44	rejected	reject	VERB
ct-9228	59	45	without	without	ADP
ct-9228	59	46	immune	immune	ADJ
ct-9228	59	47	system	system	NOUN
ct-9228	59	48	suppression	suppression	NOUN
ct-9228	59	49	in	in	ADP
ct-9228	59	50	the	the	DET
ct-9228	59	51	transplant	transplant	NOUN
ct-9228	59	52	recipient	recipient	NOUN
ct-9228	59	53	.	.	PUNCT
ct-9228	60	1	lineage	lineage	NOUN
ct-9228	60	2	restricted	restrict	VERB
ct-9228	60	3	stem	stem	NOUN
ct-9228	60	4	cells	cell	NOUN
ct-9228	60	5	the	the	DET
ct-9228	60	6	other	other	ADJ
ct-9228	60	7	major	major	ADJ
ct-9228	60	8	stem	stem	NOUN
ct-9228	60	9	cell	cell	NOUN
ct-9228	60	10	type	type	NOUN
ct-9228	60	11	is	be	AUX
ct-9228	60	12	the	the	DET
ct-9228	60	13	lineage	lineage	NOUN
ct-9228	60	14	restricted	restrict	VERB
ct-9228	60	15	stem	stem	NOUN
ct-9228	60	16	cell	cell	NOUN
ct-9228	60	17	,	,	PUNCT
ct-9228	60	18	also	also	ADV
ct-9228	60	19	referred	refer	VERB
ct-9228	60	20	to	to	ADP
ct-9228	60	21	as	as	ADP
ct-9228	60	22	somatic	somatic	ADJ
ct-9228	60	23	stem	stem	NOUN
ct-9228	60	24	cell	cell	NOUN
ct-9228	60	25	,	,	PUNCT
ct-9228	60	26	tissue	tissue	NOUN
ct-9228	60	27	stem	stem	NOUN
ct-9228	60	28	cell	cell	NOUN
ct-9228	60	29	,	,	PUNCT
ct-9228	60	30	or	or	CCONJ
ct-9228	60	31	multipotent	multipotent	NOUN
ct-9228	60	32	stem	stem	NOUN
ct-9228	60	33	cell	cell	NOUN
ct-9228	60	34	.	.	PUNCT
ct-9228	61	1	these	these	DET
ct-9228	61	2	cells	cell	NOUN
ct-9228	61	3	are	be	AUX
ct-9228	61	4	obtained	obtain	VERB
ct-9228	61	5	from	from	ADP
ct-9228	61	6	mature	mature	ADJ
ct-9228	61	7	tissues	tissue	NOUN
ct-9228	61	8	and	and	CCONJ
ct-9228	61	9	are	be	AUX
ct-9228	61	10	the	the	DET
ct-9228	61	11	natural	natural	ADJ
ct-9228	61	12	source	source	NOUN
ct-9228	61	13	of	of	ADP
ct-9228	61	14	cell	cell	NOUN
ct-9228	61	15	regeneration	regeneration	NOUN
ct-9228	61	16	in	in	ADP
ct-9228	61	17	tissues	tissue	NOUN
ct-9228	61	18	during	during	ADP
ct-9228	61	19	healing	healing	NOUN
ct-9228	61	20	or	or	CCONJ
ct-9228	61	21	other	other	ADJ
ct-9228	61	22	physiological	physiological	ADJ
ct-9228	61	23	cell	cell	NOUN
ct-9228	61	24	expansions	expansion	NOUN
ct-9228	61	25	.	.	PUNCT
ct-9228	62	1	these	these	DET
ct-9228	62	2	cells	cell	NOUN
ct-9228	62	3	are	be	AUX
ct-9228	62	4	typically	typically	ADV
ct-9228	62	5	restricted	restrict	VERB
ct-9228	62	6	to	to	ADP
ct-9228	62	7	differentiation	differentiation	NOUN
ct-9228	62	8	into	into	ADP
ct-9228	62	9	cells	cell	NOUN
ct-9228	62	10	within	within	ADP
ct-9228	62	11	their	their	PRON
ct-9228	62	12	own	own	ADJ
ct-9228	62	13	germ	germ	NOUN
ct-9228	62	14	layer	layer	NOUN
ct-9228	62	15	,	,	PUNCT
ct-9228	62	16	or	or	CCONJ
ct-9228	62	17	even	even	ADV
ct-9228	62	18	within	within	ADP
ct-9228	62	19	their	their	PRON
ct-9228	62	20	own	own	ADJ
ct-9228	62	21	tissue	tissue	NOUN
ct-9228	62	22	.	.	PUNCT
ct-9228	63	1	advantages	advantage	NOUN
ct-9228	63	2	and	and	CCONJ
ct-9228	63	3	disadvantages	disadvantage	NOUN
ct-9228	63	4	of	of	ADP
ct-9228	63	5	lineage	lineage	NOUN
ct-9228	63	6	restricted	restrict	VERB
ct-9228	63	7	stem	stem	NOUN
ct-9228	63	8	cells	cell	NOUN
ct-9228	63	9	:	:	PUNCT
ct-9228	63	10	the	the	DET
ct-9228	63	11	major	major	ADJ
ct-9228	63	12	disadvantage	disadvantage	NOUN
ct-9228	63	13	of	of	ADP
ct-9228	63	14	lineage	lineage	NOUN
ct-9228	63	15	restricted	restrict	VERB
ct-9228	63	16	stem	stem	NOUN
ct-9228	63	17	cells	cell	NOUN
ct-9228	63	18	is	be	AUX
ct-9228	63	19	that	that	SCONJ
ct-9228	63	20	they	they	PRON
ct-9228	63	21	are	be	AUX
ct-9228	63	22	not	not	PART
ct-9228	63	23	pluripotent	pluripotent	ADJ
ct-9228	63	24	.	.	PUNCT
ct-9228	64	1	they	they	PRON
ct-9228	64	2	can	can	AUX
ct-9228	64	3	become	become	VERB
ct-9228	64	4	some	some	DET
ct-9228	64	5	cell	cell	NOUN
ct-9228	64	6	types	type	NOUN
ct-9228	64	7	in	in	ADP
ct-9228	64	8	the	the	DET
ct-9228	64	9	body	body	NOUN
ct-9228	64	10	,	,	PUNCT
ct-9228	64	11	but	but	CCONJ
ct-9228	64	12	not	not	PART
ct-9228	64	13	all	all	PRON
ct-9228	64	14	.	.	PUNCT
ct-9228	65	1	however	however	ADV
ct-9228	65	2	,	,	PUNCT
ct-9228	65	3	for	for	ADP
ct-9228	65	4	clinical	clinical	ADJ
ct-9228	65	5	purposes	purpose	NOUN
ct-9228	65	6	,	,	PUNCT
ct-9228	65	7	they	they	PRON
ct-9228	65	8	have	have	VERB
ct-9228	65	9	some	some	DET
ct-9228	65	10	significant	significant	ADJ
ct-9228	65	11	advantages	advantage	NOUN
ct-9228	65	12	.	.	PUNCT
ct-9228	66	1	first	first	ADV
ct-9228	66	2	,	,	PUNCT
ct-9228	66	3	since	since	SCONJ
ct-9228	66	4	they	they	PRON
ct-9228	66	5	are	be	AUX
ct-9228	66	6	not	not	PART
ct-9228	66	7	pluripotent	pluripotent	ADJ
ct-9228	66	8	,	,	PUNCT
ct-9228	66	9	they	they	PRON
ct-9228	66	10	will	will	AUX
ct-9228	66	11	not	not	PART
ct-9228	66	12	form	form	VERB
ct-9228	66	13	teratomas	teratoma	NOUN
ct-9228	66	14	upon	upon	SCONJ
ct-9228	66	15	transplantation	transplantation	NOUN
ct-9228	66	16	.	.	PUNCT
ct-9228	67	1	second	second	ADJ
ct-9228	67	2	,	,	PUNCT
ct-9228	67	3	they	they	PRON
ct-9228	67	4	have	have	VERB
ct-9228	67	5	a	a	DET
ct-9228	67	6	long	long	ADJ
ct-9228	67	7	history	history	NOUN
ct-9228	67	8	of	of	ADP
ct-9228	67	9	clinical	clinical	ADJ
ct-9228	67	10	use	use	NOUN
ct-9228	67	11	,	,	PUNCT
ct-9228	67	12	demonstrating	demonstrate	VERB
ct-9228	67	13	safety	safety	NOUN
ct-9228	67	14	and	and	CCONJ
ct-9228	67	15	efficacy	efficacy	NOUN
ct-9228	67	16	.	.	PUNCT
ct-9228	68	1	some	some	DET
ct-9228	68	2	examples	example	NOUN
ct-9228	68	3	include	include	VERB
ct-9228	68	4	hematopoietic	hematopoietic	ADJ
ct-9228	68	5	stem	stem	NOUN
ct-9228	68	6	cells	cell	NOUN
ct-9228	68	7	,	,	PUNCT
ct-9228	68	8	mesenchymal	mesenchymal	ADJ
ct-9228	68	9	stem	stem	NOUN
ct-9228	68	10	cells	cell	NOUN
ct-9228	68	11	,	,	PUNCT
ct-9228	68	12	and	and	CCONJ
ct-9228	68	13	tissue	tissue	NOUN
ct-9228	68	14	-	-	PUNCT
ct-9228	68	15	specific	specific	ADJ
ct-9228	68	16	stem	stem	NOUN
ct-9228	68	17	cells	cell	NOUN
ct-9228	68	18	.	.	PUNCT
ct-9228	69	1	hematopoietic	hematopoietic	ADJ
ct-9228	69	2	stem	stem	NOUN
ct-9228	69	3	cells	cell	NOUN
ct-9228	69	4	have	have	AUX
ct-9228	69	5	been	be	AUX
ct-9228	69	6	in	in	ADP
ct-9228	69	7	use	use	NOUN
ct-9228	69	8	in	in	ADP
ct-9228	69	9	the	the	DET
ct-9228	69	10	clinical	clinical	ADJ
ct-9228	69	11	setting	setting	NOUN
ct-9228	69	12	for	for	ADP
ct-9228	69	13	decades	decade	NOUN
ct-9228	69	14	,	,	PUNCT
ct-9228	69	15	particularly	particularly	ADV
ct-9228	69	16	in	in	ADP
ct-9228	69	17	the	the	DET
ct-9228	69	18	treatment	treatment	NOUN
ct-9228	69	19	of	of	ADP
ct-9228	69	20	cancer	cancer	NOUN
ct-9228	69	21	.	.	PUNCT
ct-9228	70	1	for	for	ADP
ct-9228	70	2	this	this	DET
ct-9228	70	3	purpose	purpose	NOUN
ct-9228	70	4	,	,	PUNCT
ct-9228	70	5	a	a	DET
ct-9228	70	6	person	person	NOUN
ct-9228	70	7	’s	’s	PART
ct-9228	70	8	natural	natural	ADJ
ct-9228	70	9	hematopoietic	hematopoietic	ADJ
ct-9228	70	10	stem	stem	NOUN
ct-9228	70	11	cells	cell	NOUN
ct-9228	70	12	are	be	AUX
ct-9228	70	13	destroyed	destroy	VERB
ct-9228	70	14	and	and	CCONJ
ct-9228	70	15	replaced	replace	VERB
ct-9228	70	16	using	use	VERB
ct-9228	70	17	donated	donate	VERB
ct-9228	70	18	bone	bone	NOUN
ct-9228	70	19	marrow	marrow	NOUN
ct-9228	70	20	,	,	PUNCT
ct-9228	70	21	a	a	DET
ct-9228	70	22	major	major	ADJ
ct-9228	70	23	source	source	NOUN
ct-9228	70	24	of	of	ADP
ct-9228	70	25	hematopoietic	hematopoietic	ADJ
ct-9228	70	26	stem	stem	NOUN
ct-9228	70	27	cells.23	cells.23	PROPN
ct-9228	70	28	mesenchymal	mesenchymal	NOUN
ct-9228	70	29	stem	stem	NOUN
ct-9228	70	30	cells	cell	NOUN
ct-9228	70	31	are	be	AUX
ct-9228	70	32	highly	highly	ADV
ct-9228	70	33	versatile	versatile	ADJ
ct-9228	70	34	,	,	PUNCT
ct-9228	70	35	although	although	SCONJ
ct-9228	70	36	their	their	PRON
ct-9228	70	37	differentiation	differentiation	NOUN
ct-9228	70	38	capabilities	capability	NOUN
ct-9228	70	39	are	be	AUX
ct-9228	70	40	controversial	controversial	ADJ
ct-9228	70	41	.	.	PUNCT
ct-9228	71	1	initial	initial	ADJ
ct-9228	71	2	studies	study	NOUN
ct-9228	71	3	demonstrated	demonstrate	VERB
ct-9228	71	4	increased	increase	VERB
ct-9228	71	5	proliferation	proliferation	NOUN
ct-9228	71	6	of	of	ADP
ct-9228	71	7	mature	mature	ADJ
ct-9228	71	8	cell	cell	NOUN
ct-9228	71	9	types	type	NOUN
ct-9228	71	10	in	in	ADP
ct-9228	71	11	many	many	ADJ
ct-9228	71	12	organs	organ	NOUN
ct-9228	71	13	,	,	PUNCT
ct-9228	71	14	including	include	VERB
ct-9228	71	15	from	from	ADP
ct-9228	71	16	other	other	ADJ
ct-9228	71	17	germ	germ	NOUN
ct-9228	71	18	layers	layer	NOUN
ct-9228	71	19	,	,	PUNCT
ct-9228	71	20	after	after	ADP
ct-9228	71	21	the	the	DET
ct-9228	71	22	injection	injection	NOUN
ct-9228	71	23	of	of	ADP
ct-9228	71	24	mesenchymal	mesenchymal	ADJ
ct-9228	71	25	stem	stem	NOUN
ct-9228	71	26	cells	cell	NOUN
ct-9228	71	27	,	,	PUNCT
ct-9228	71	28	leading	lead	VERB
ct-9228	71	29	to	to	ADP
ct-9228	71	30	speculation	speculation	NOUN
ct-9228	71	31	that	that	SCONJ
ct-9228	71	32	these	these	DET
ct-9228	71	33	cells	cell	NOUN
ct-9228	71	34	could	could	AUX
ct-9228	71	35	be	be	AUX
ct-9228	71	36	pluripotent.24	pluripotent.24	NOUN
ct-9228	71	37	other	other	ADJ
ct-9228	71	38	studies	study	NOUN
ct-9228	71	39	that	that	PRON
ct-9228	71	40	traced	trace	VERB
ct-9228	71	41	the	the	DET
ct-9228	71	42	source	source	NOUN
ct-9228	71	43	of	of	ADP
ct-9228	71	44	increased	increase	VERB
ct-9228	71	45	cell	cell	NOUN
ct-9228	71	46	proliferation	proliferation	NOUN
ct-9228	71	47	after	after	ADP
ct-9228	71	48	mesenchymal	mesenchymal	NOUN
ct-9228	71	49	stem	stem	NOUN
ct-9228	71	50	cell	cell	NOUN
ct-9228	71	51	transplantation	transplantation	NOUN
ct-9228	71	52	demonstrated	demonstrate	VERB
ct-9228	71	53	that	that	SCONJ
ct-9228	71	54	the	the	DET
ct-9228	71	55	new	new	ADJ
ct-9228	71	56	cells	cell	NOUN
ct-9228	71	57	generated	generate	VERB
ct-9228	71	58	do	do	AUX
ct-9228	71	59	not	not	PART
ct-9228	71	60	come	come	VERB
ct-9228	71	61	from	from	ADP
ct-9228	71	62	the	the	DET
ct-9228	71	63	transplant	transplant	NOUN
ct-9228	71	64	,	,	PUNCT
ct-9228	71	65	but	but	CCONJ
ct-9228	71	66	from	from	ADP
ct-9228	71	67	the	the	DET
ct-9228	71	68	tissue	tissue	NOUN
ct-9228	71	69	,	,	PUNCT
ct-9228	71	70	suggesting	suggest	VERB
ct-9228	71	71	that	that	SCONJ
ct-9228	71	72	mesenchymal	mesenchymal	NOUN
ct-9228	71	73	stem	stem	NOUN
ct-9228	71	74	cells	cell	NOUN
ct-9228	71	75	are	be	AUX
ct-9228	71	76	powerful	powerful	ADJ
ct-9228	71	77	endocrine	endocrine	ADJ
ct-9228	71	78	modulators	modulator	NOUN
ct-9228	71	79	that	that	PRON
ct-9228	71	80	activate	activate	VERB
ct-9228	71	81	endogenous	endogenous	ADJ
ct-9228	71	82	tissue	tissue	NOUN
ct-9228	71	83	stem	stem	NOUN
ct-9228	71	84	cells	cell	NOUN
ct-9228	71	85	without	without	ADP
ct-9228	71	86	directly	directly	ADV
ct-9228	71	87	contributing	contribute	VERB
ct-9228	71	88	to	to	ADP
ct-9228	71	89	the	the	DET
ct-9228	71	90	tissue.25	tissue.25	PROPN
ct-9228	71	91	other	other	ADJ
ct-9228	71	92	tissue	tissue	NOUN
ct-9228	71	93	specific	specific	ADJ
ct-9228	71	94	stem	stem	NOUN
ct-9228	71	95	cells	cell	NOUN
ct-9228	71	96	are	be	AUX
ct-9228	71	97	known	know	VERB
ct-9228	71	98	to	to	PART
ct-9228	71	99	exist	exist	VERB
ct-9228	71	100	through	through	ADP
ct-9228	71	101	their	their	PRON
ct-9228	71	102	properties	property	NOUN
ct-9228	71	103	:	:	PUNCT
ct-9228	71	104	the	the	DET
ct-9228	71	105	ability	ability	NOUN
ct-9228	71	106	to	to	PART
ct-9228	71	107	proliferate	proliferate	VERB
ct-9228	71	108	to	to	PART
ct-9228	71	109	maintain	maintain	VERB
ct-9228	71	110	the	the	DET
ct-9228	71	111	tissue	tissue	NOUN
ct-9228	71	112	stem	stem	NOUN
ct-9228	71	113	cell	cell	NOUN
ct-9228	71	114	reservoir	reservoir	NOUN
ct-9228	71	115	while	while	SCONJ
ct-9228	71	116	at	at	ADP
ct-9228	71	117	the	the	DET
ct-9228	71	118	same	same	ADJ
ct-9228	71	119	time	time	NOUN
ct-9228	71	120	providing	provide	VERB
ct-9228	71	121	cells	cell	NOUN
ct-9228	71	122	for	for	ADP
ct-9228	71	123	differentiation	differentiation	NOUN
ct-9228	71	124	into	into	ADP
ct-9228	71	125	mature	mature	ADJ
ct-9228	71	126	cell	cell	NOUN
ct-9228	71	127	types	type	NOUN
ct-9228	71	128	.	.	PUNCT
ct-9228	72	1	an	an	DET
ct-9228	72	2	example	example	NOUN
ct-9228	72	3	is	be	AUX
ct-9228	72	4	spermatogonial	spermatogonial	ADJ
ct-9228	72	5	stem	stem	NOUN
ct-9228	72	6	cells	cell	NOUN
ct-9228	72	7	,	,	PUNCT
ct-9228	72	8	which	which	PRON
ct-9228	72	9	have	have	AUX
ct-9228	72	10	been	be	AUX
ct-9228	72	11	clinical	clinical	ADJ
ct-9228	72	12	theriogenology	theriogenology	NOUN
ct-9228	72	13	•	•	NOUN
ct-9228	72	14	volume	volume	NOUN
ct-9228	72	15	12	12	NUM
ct-9228	72	16	number	number	NOUN
ct-9228	72	17	3	3	NUM
ct-9228	72	18	•	•	NUM
ct-9228	72	19	september	september	PROPN
ct-9228	72	20	2020	2020	NUM
ct-9228	72	21	185	185	NUM
ct-9228	72	22	characterized	characterize	VERB
ct-9228	72	23	by	by	ADP
ct-9228	72	24	their	their	PRON
ct-9228	72	25	properties	property	NOUN
ct-9228	72	26	in	in	ADP
ct-9228	72	27	the	the	DET
ct-9228	72	28	testes	testis	NOUN
ct-9228	72	29	,	,	PUNCT
ct-9228	72	30	although	although	SCONJ
ct-9228	72	31	they	they	PRON
ct-9228	72	32	are	be	AUX
ct-9228	72	33	difficult	difficult	ADJ
ct-9228	72	34	to	to	PART
ct-9228	72	35	specifically	specifically	ADV
ct-9228	72	36	isolate	isolate	VERB
ct-9228	72	37	for	for	ADP
ct-9228	72	38	study.26,27	study.26,27	ADJ
ct-9228	72	39	totipotent	totipotent	ADJ
ct-9228	72	40	stem	stem	NOUN
ct-9228	72	41	cells	cell	NOUN
ct-9228	72	42	totipotent	totipotent	ADJ
ct-9228	72	43	stem	stem	NOUN
ct-9228	72	44	cells	cell	NOUN
ct-9228	72	45	are	be	AUX
ct-9228	72	46	the	the	PRON
ct-9228	72	47	least	least	ADV
ct-9228	72	48	understood	understand	VERB
ct-9228	72	49	and	and	CCONJ
ct-9228	72	50	also	also	ADV
ct-9228	72	51	the	the	DET
ct-9228	72	52	least	least	ADJ
ct-9228	72	53	studied	study	VERB
ct-9228	72	54	,	,	PUNCT
ct-9228	72	55	but	but	CCONJ
ct-9228	72	56	they	they	PRON
ct-9228	72	57	are	be	AUX
ct-9228	72	58	known	know	VERB
ct-9228	72	59	to	to	PART
ct-9228	72	60	exist	exist	VERB
ct-9228	72	61	by	by	ADP
ct-9228	72	62	their	their	PRON
ct-9228	72	63	function	function	NOUN
ct-9228	72	64	.	.	PUNCT
ct-9228	73	1	these	these	DET
ct-9228	73	2	cells	cell	NOUN
ct-9228	73	3	distinguish	distinguish	VERB
ct-9228	73	4	themselves	themselves	PRON
ct-9228	73	5	from	from	ADP
ct-9228	73	6	pluripotent	pluripotent	ADJ
ct-9228	73	7	stem	stem	NOUN
ct-9228	73	8	cells	cell	NOUN
ct-9228	73	9	because	because	SCONJ
ct-9228	73	10	they	they	PRON
ct-9228	73	11	can	can	AUX
ct-9228	73	12	become	become	VERB
ct-9228	73	13	any	any	DET
ct-9228	73	14	cell	cell	NOUN
ct-9228	73	15	type	type	NOUN
ct-9228	73	16	in	in	ADP
ct-9228	73	17	the	the	DET
ct-9228	73	18	body	body	NOUN
ct-9228	73	19	(	(	PUNCT
ct-9228	73	20	as	as	SCONJ
ct-9228	73	21	pluripotent	pluripotent	ADJ
ct-9228	73	22	cells	cell	NOUN
ct-9228	73	23	can	can	AUX
ct-9228	73	24	)	)	PUNCT
ct-9228	73	25	as	as	ADV
ct-9228	73	26	well	well	ADV
ct-9228	73	27	as	as	ADP
ct-9228	73	28	the	the	DET
ct-9228	73	29	placenta	placenta	NOUN
ct-9228	73	30	(	(	PUNCT
ct-9228	73	31	pluripotent	pluripotent	ADJ
ct-9228	73	32	cells	cell	NOUN
ct-9228	73	33	cannot).2	cannot).2	PROPN
ct-9228	73	34	these	these	DET
ct-9228	73	35	cells	cell	NOUN
ct-9228	73	36	exist	exist	VERB
ct-9228	73	37	in	in	ADP
ct-9228	73	38	the	the	DET
ct-9228	73	39	very	very	ADV
ct-9228	73	40	earliest	early	ADJ
ct-9228	73	41	stages	stage	NOUN
ct-9228	73	42	of	of	ADP
ct-9228	73	43	development	development	NOUN
ct-9228	73	44	before	before	ADP
ct-9228	73	45	the	the	DET
ct-9228	73	46	blastocyst	blastocyst	NOUN
ct-9228	73	47	forms	form	NOUN
ct-9228	73	48	;	;	PUNCT
ct-9228	73	49	however	however	ADV
ct-9228	73	50	,	,	PUNCT
ct-9228	73	51	because	because	SCONJ
ct-9228	73	52	they	they	PRON
ct-9228	73	53	have	have	AUX
ct-9228	73	54	not	not	PART
ct-9228	73	55	been	be	AUX
ct-9228	73	56	isolated	isolate	VERB
ct-9228	73	57	or	or	CCONJ
ct-9228	73	58	grown	grow	VERB
ct-9228	73	59	in	in	ADP
ct-9228	73	60	culture	culture	NOUN
ct-9228	73	61	,	,	PUNCT
ct-9228	73	62	relatively	relatively	ADV
ct-9228	73	63	little	little	ADJ
ct-9228	73	64	is	be	AUX
ct-9228	73	65	known	know	VERB
ct-9228	73	66	about	about	ADP
ct-9228	73	67	their	their	PRON
ct-9228	73	68	biology.28	biology.28	NOUN
ct-9228	73	69	cell	cell	NOUN
ct-9228	73	70	fate	fate	NOUN
ct-9228	73	71	specification	specification	NOUN
ct-9228	73	72	given	give	VERB
ct-9228	73	73	that	that	SCONJ
ct-9228	73	74	the	the	DET
ct-9228	73	75	uses	use	NOUN
ct-9228	73	76	of	of	ADP
ct-9228	73	77	stem	stem	NOUN
ct-9228	73	78	cells	cell	NOUN
ct-9228	73	79	that	that	PRON
ct-9228	73	80	generate	generate	VERB
ct-9228	73	81	the	the	DET
ct-9228	73	82	most	most	ADJ
ct-9228	73	83	interest	interest	NOUN
ct-9228	73	84	are	be	AUX
ct-9228	73	85	for	for	ADP
ct-9228	73	86	regeneration	regeneration	NOUN
ct-9228	73	87	of	of	ADP
ct-9228	73	88	somatic	somatic	ADJ
ct-9228	73	89	cells	cell	NOUN
ct-9228	73	90	for	for	ADP
ct-9228	73	91	clinical	clinical	ADJ
ct-9228	73	92	and	and	CCONJ
ct-9228	73	93	research	research	NOUN
ct-9228	73	94	uses	use	NOUN
ct-9228	73	95	,	,	PUNCT
ct-9228	73	96	understanding	understand	VERB
ct-9228	73	97	the	the	DET
ct-9228	73	98	tenets	tenet	NOUN
ct-9228	73	99	of	of	ADP
ct-9228	73	100	cell	cell	NOUN
ct-9228	73	101	fate	fate	NOUN
ct-9228	73	102	specification	specification	NOUN
ct-9228	73	103	are	be	AUX
ct-9228	73	104	key	key	ADJ
ct-9228	73	105	to	to	ADP
ct-9228	73	106	utility	utility	NOUN
ct-9228	73	107	of	of	ADP
ct-9228	73	108	stem	stem	NOUN
ct-9228	73	109	cells	cell	NOUN
ct-9228	73	110	.	.	PUNCT
ct-9228	74	1	two	two	NUM
ct-9228	74	2	approaches	approach	NOUN
ct-9228	74	3	to	to	PART
ct-9228	74	4	cell	cell	NOUN
ct-9228	74	5	fate	fate	NOUN
ct-9228	74	6	specification	specification	NOUN
ct-9228	74	7	are	be	AUX
ct-9228	74	8	direct	direct	ADJ
ct-9228	74	9	reprogramming	reprogramming	NOUN
ct-9228	74	10	of	of	ADP
ct-9228	74	11	somatic	somatic	ADJ
ct-9228	74	12	cells	cell	NOUN
ct-9228	74	13	and	and	CCONJ
ct-9228	74	14	use	use	NOUN
ct-9228	74	15	of	of	ADP
ct-9228	74	16	developmental	developmental	ADJ
ct-9228	74	17	biology	biology	NOUN
ct-9228	74	18	signaling	signal	VERB
ct-9228	74	19	programs	program	NOUN
ct-9228	74	20	for	for	ADP
ct-9228	74	21	specification	specification	NOUN
ct-9228	74	22	.	.	PUNCT
ct-9228	75	1	in	in	ADP
ct-9228	75	2	direct	direct	ADJ
ct-9228	75	3	reprogramming	reprogramming	ADJ
ct-9228	75	4	,	,	PUNCT
ct-9228	75	5	somatic	somatic	ADJ
ct-9228	75	6	cells	cell	NOUN
ct-9228	75	7	of	of	ADP
ct-9228	75	8	1	1	NUM
ct-9228	75	9	type	type	NOUN
ct-9228	75	10	are	be	AUX
ct-9228	75	11	treated	treat	VERB
ct-9228	75	12	with	with	ADP
ct-9228	75	13	cocktails	cocktail	NOUN
ct-9228	75	14	(	(	PUNCT
ct-9228	75	15	genetic	genetic	ADJ
ct-9228	75	16	,	,	PUNCT
ct-9228	75	17	protein	protein	NOUN
ct-9228	75	18	,	,	PUNCT
ct-9228	75	19	or	or	CCONJ
ct-9228	75	20	small	small	ADJ
ct-9228	75	21	molecules	molecule	NOUN
ct-9228	75	22	)	)	PUNCT
ct-9228	75	23	to	to	PART
ct-9228	75	24	directly	directly	ADV
ct-9228	75	25	turn	turn	VERB
ct-9228	75	26	1	1	NUM
ct-9228	75	27	cell	cell	NOUN
ct-9228	75	28	type	type	NOUN
ct-9228	75	29	into	into	ADP
ct-9228	75	30	another	another	PRON
ct-9228	75	31	.	.	PUNCT
ct-9228	76	1	this	this	DET
ct-9228	76	2	approach	approach	NOUN
ct-9228	76	3	skips	skip	VERB
ct-9228	76	4	the	the	DET
ct-9228	76	5	intermediate	intermediate	ADJ
ct-9228	76	6	step	step	NOUN
ct-9228	76	7	of	of	ADP
ct-9228	76	8	creating	create	VERB
ct-9228	76	9	a	a	DET
ct-9228	76	10	stem	stem	NOUN
ct-9228	76	11	cell	cell	NOUN
ct-9228	76	12	,	,	PUNCT
ct-9228	76	13	which	which	PRON
ct-9228	76	14	makes	make	VERB
ct-9228	76	15	it	it	PRON
ct-9228	76	16	relatively	relatively	ADV
ct-9228	76	17	fast	fast	ADV
ct-9228	76	18	.	.	PUNCT
ct-9228	77	1	the	the	DET
ct-9228	77	2	biological	biological	ADJ
ct-9228	77	3	methods	method	NOUN
ct-9228	77	4	for	for	ADP
ct-9228	77	5	this	this	PRON
ct-9228	77	6	are	be	AUX
ct-9228	77	7	still	still	ADV
ct-9228	77	8	being	be	AUX
ct-9228	77	9	refined	refine	VERB
ct-9228	77	10	,	,	PUNCT
ct-9228	77	11	but	but	CCONJ
ct-9228	77	12	it	it	PRON
ct-9228	77	13	has	have	AUX
ct-9228	77	14	been	be	AUX
ct-9228	77	15	accomplished	accomplish	VERB
ct-9228	77	16	for	for	ADP
ct-9228	77	17	some	some	DET
ct-9228	77	18	applications	application	NOUN
ct-9228	77	19	,	,	PUNCT
ct-9228	77	20	such	such	ADJ
ct-9228	77	21	as	as	ADP
ct-9228	77	22	turning	turn	VERB
ct-9228	77	23	fibroblasts	fibroblast	NOUN
ct-9228	77	24	into	into	ADP
ct-9228	77	25	neurons.29	neurons.29	NOUN
ct-9228	77	26	however	however	ADV
ct-9228	77	27	,	,	PUNCT
ct-9228	77	28	the	the	DET
ct-9228	77	29	methods	method	NOUN
ct-9228	77	30	are	be	AUX
ct-9228	77	31	experimental	experimental	ADJ
ct-9228	77	32	,	,	PUNCT
ct-9228	77	33	and	and	CCONJ
ct-9228	77	34	it	it	PRON
ct-9228	77	35	has	have	VERB
ct-9228	77	36	yet	yet	ADV
ct-9228	77	37	to	to	PART
ct-9228	77	38	be	be	AUX
ct-9228	77	39	done	do	VERB
ct-9228	77	40	under	under	ADP
ct-9228	77	41	gmp	gmp	PROPN
ct-9228	77	42	conditions	condition	NOUN
ct-9228	77	43	.	.	PUNCT
ct-9228	78	1	additionally	additionally	ADV
ct-9228	78	2	,	,	PUNCT
ct-9228	78	3	because	because	SCONJ
ct-9228	78	4	it	it	PRON
ct-9228	78	5	eliminates	eliminate	VERB
ct-9228	78	6	the	the	DET
ct-9228	78	7	intermediate	intermediate	ADJ
ct-9228	78	8	step	step	NOUN
ct-9228	78	9	of	of	ADP
ct-9228	78	10	creating	create	VERB
ct-9228	78	11	an	an	DET
ct-9228	78	12	immortal	immortal	ADJ
ct-9228	78	13	stem	stem	NOUN
ct-9228	78	14	cell	cell	NOUN
ct-9228	78	15	that	that	PRON
ct-9228	78	16	allows	allow	VERB
ct-9228	78	17	for	for	ADP
ct-9228	78	18	rapid	rapid	ADJ
ct-9228	78	19	expansion	expansion	NOUN
ct-9228	78	20	,	,	PUNCT
ct-9228	78	21	it	it	PRON
ct-9228	78	22	is	be	AUX
ct-9228	78	23	not	not	PART
ct-9228	78	24	ideal	ideal	ADJ
ct-9228	78	25	when	when	SCONJ
ct-9228	78	26	starting	start	VERB
ct-9228	78	27	material	material	NOUN
ct-9228	78	28	is	be	AUX
ct-9228	78	29	limited	limit	VERB
ct-9228	78	30	.	.	PUNCT
ct-9228	79	1	the	the	DET
ct-9228	79	2	more	more	ADV
ct-9228	79	3	established	establish	VERB
ct-9228	79	4	approach	approach	NOUN
ct-9228	79	5	is	be	AUX
ct-9228	79	6	to	to	PART
ct-9228	79	7	use	use	VERB
ct-9228	79	8	the	the	DET
ct-9228	79	9	known	know	VERB
ct-9228	79	10	signaling	signal	VERB
ct-9228	79	11	pathways	pathway	NOUN
ct-9228	79	12	of	of	ADP
ct-9228	79	13	developmental	developmental	ADJ
ct-9228	79	14	biology	biology	NOUN
ct-9228	79	15	to	to	PART
ct-9228	79	16	specify	specify	VERB
ct-9228	79	17	cell	cell	NOUN
ct-9228	79	18	fate	fate	NOUN
ct-9228	79	19	.	.	PUNCT
ct-9228	80	1	this	this	DET
ct-9228	80	2	technique	technique	NOUN
ct-9228	80	3	can	can	AUX
ct-9228	80	4	be	be	AUX
ct-9228	80	5	used	use	VERB
ct-9228	80	6	starting	start	VERB
ct-9228	80	7	from	from	ADP
ct-9228	80	8	pluripotent	pluripotent	ADJ
ct-9228	80	9	stem	stem	NOUN
ct-9228	80	10	cells	cell	NOUN
ct-9228	80	11	,	,	PUNCT
ct-9228	80	12	by	by	ADP
ct-9228	80	13	initiating	initiate	VERB
ct-9228	80	14	primitive	primitive	ADJ
ct-9228	80	15	streak	streak	NOUN
ct-9228	80	16	specification	specification	NOUN
ct-9228	80	17	,	,	PUNCT
ct-9228	80	18	or	or	CCONJ
ct-9228	80	19	it	it	PRON
ct-9228	80	20	can	can	AUX
ct-9228	80	21	be	be	AUX
ct-9228	80	22	used	use	VERB
ct-9228	80	23	on	on	ADP
ct-9228	80	24	lineage	lineage	NOUN
ct-9228	80	25	restricted	restrict	VERB
ct-9228	80	26	stem	stem	NOUN
ct-9228	80	27	cells	cell	NOUN
ct-9228	80	28	by	by	ADP
ct-9228	80	29	initiating	initiate	VERB
ct-9228	80	30	maturation	maturation	NOUN
ct-9228	80	31	of	of	ADP
ct-9228	80	32	tissue	tissue	NOUN
ct-9228	80	33	specific	specific	ADJ
ct-9228	80	34	progenitors	progenitor	NOUN
ct-9228	80	35	into	into	ADP
ct-9228	80	36	mature	mature	ADJ
ct-9228	80	37	cell	cell	NOUN
ct-9228	80	38	types	type	NOUN
ct-9228	80	39	.	.	PUNCT
ct-9228	81	1	pluripotent	pluripotent	ADJ
ct-9228	81	2	stem	stem	NOUN
ct-9228	81	3	cells	cell	NOUN
ct-9228	81	4	can	can	AUX
ct-9228	81	5	be	be	AUX
ct-9228	81	6	guided	guide	VERB
ct-9228	81	7	through	through	ADP
ct-9228	81	8	specification	specification	NOUN
ct-9228	81	9	to	to	PART
ct-9228	81	10	endoderm	endoderm	VERB
ct-9228	81	11	,	,	PUNCT
ct-9228	81	12	mesoderm	mesoderm	NOUN
ct-9228	81	13	,	,	PUNCT
ct-9228	81	14	or	or	CCONJ
ct-9228	81	15	ectoderm	ectoderm	NOUN
ct-9228	81	16	then	then	ADV
ct-9228	81	17	to	to	PART
ct-9228	81	18	mature	mature	VERB
ct-9228	81	19	cells	cell	NOUN
ct-9228	81	20	within	within	ADP
ct-9228	81	21	each	each	DET
ct-9228	81	22	germ	germ	NOUN
ct-9228	81	23	layer	layer	NOUN
ct-9228	81	24	using	use	VERB
ct-9228	81	25	developmental	developmental	ADJ
ct-9228	81	26	growth	growth	NOUN
ct-9228	81	27	factors	factor	NOUN
ct-9228	81	28	or	or	CCONJ
ct-9228	81	29	with	with	ADP
ct-9228	81	30	small	small	ADJ
ct-9228	81	31	molecule	molecule	NOUN
ct-9228	81	32	analogues	analogue	NOUN
ct-9228	81	33	that	that	PRON
ct-9228	81	34	evoke	evoke	VERB
ct-9228	81	35	the	the	DET
ct-9228	81	36	equivalent	equivalent	ADJ
ct-9228	81	37	cellular	cellular	ADJ
ct-9228	81	38	signaling	signal	VERB
ct-9228	81	39	response.30	response.30	NOUN
ct-9228	81	40	bioengineered	bioengineere	VERB
ct-9228	81	41	matrices	matrix	NOUN
ct-9228	81	42	can	can	AUX
ct-9228	81	43	also	also	ADV
ct-9228	81	44	contribute	contribute	VERB
ct-9228	81	45	to	to	ADP
ct-9228	81	46	cellular	cellular	ADJ
ct-9228	81	47	signaling	signal	VERB
ct-9228	81	48	to	to	ADP
ct-9228	81	49	direct	direct	ADJ
ct-9228	81	50	differentiation	differentiation	NOUN
ct-9228	81	51	.	.	PUNCT
ct-9228	82	1	confirmatory	confirmatory	NOUN
ct-9228	82	2	assays	assay	NOUN
ct-9228	82	3	similar	similar	ADJ
ct-9228	82	4	to	to	ADP
ct-9228	82	5	the	the	DET
ct-9228	82	6	confirmation	confirmation	NOUN
ct-9228	82	7	of	of	ADP
ct-9228	82	8	pluripotency	pluripotency	NOUN
ct-9228	82	9	,	,	PUNCT
ct-9228	82	10	there	there	PRON
ct-9228	82	11	are	be	VERB
ct-9228	82	12	multiple	multiple	ADJ
ct-9228	82	13	tests	test	NOUN
ct-9228	82	14	of	of	ADP
ct-9228	82	15	varying	vary	VERB
ct-9228	82	16	rigor	rigor	NOUN
ct-9228	82	17	for	for	ADP
ct-9228	82	18	verifying	verify	VERB
ct-9228	82	19	the	the	DET
ct-9228	82	20	effectiveness	effectiveness	NOUN
ct-9228	82	21	of	of	ADP
ct-9228	82	22	directed	direct	VERB
ct-9228	82	23	differentiation	differentiation	NOUN
ct-9228	82	24	.	.	PUNCT
ct-9228	83	1	the	the	DET
ct-9228	83	2	least	least	ADJ
ct-9228	83	3	rigorous	rigorous	ADJ
ct-9228	83	4	is	be	AUX
ct-9228	83	5	analysis	analysis	NOUN
ct-9228	83	6	of	of	ADP
ct-9228	83	7	the	the	DET
ct-9228	83	8	gene	gene	NOUN
ct-9228	83	9	expression	expression	NOUN
ct-9228	83	10	profile	profile	NOUN
ct-9228	83	11	,	,	PUNCT
ct-9228	83	12	i.e.	i.e.	X
ct-9228	83	13	mrna	mrna	PROPN
ct-9228	83	14	from	from	ADP
ct-9228	83	15	differentiated	differentiated	ADJ
ct-9228	83	16	cells	cell	NOUN
ct-9228	83	17	can	can	AUX
ct-9228	83	18	be	be	AUX
ct-9228	83	19	analyzed	analyze	VERB
ct-9228	83	20	to	to	PART
ct-9228	83	21	determine	determine	VERB
ct-9228	83	22	if	if	SCONJ
ct-9228	83	23	the	the	DET
ct-9228	83	24	expression	expression	NOUN
ct-9228	83	25	profile	profile	NOUN
ct-9228	83	26	matches	match	VERB
ct-9228	83	27	that	that	PRON
ct-9228	83	28	of	of	ADP
ct-9228	83	29	a	a	DET
ct-9228	83	30	somatic	somatic	ADJ
ct-9228	83	31	cell	cell	NOUN
ct-9228	83	32	of	of	ADP
ct-9228	83	33	the	the	DET
ct-9228	83	34	same	same	ADJ
ct-9228	83	35	type	type	NOUN
ct-9228	83	36	that	that	PRON
ct-9228	83	37	is	be	AUX
ct-9228	83	38	obtained	obtain	VERB
ct-9228	83	39	directly	directly	ADV
ct-9228	83	40	from	from	ADP
ct-9228	83	41	the	the	DET
ct-9228	83	42	tissue	tissue	NOUN
ct-9228	83	43	of	of	ADP
ct-9228	83	44	interest	interest	NOUN
ct-9228	83	45	.	.	PUNCT
ct-9228	84	1	similarly	similarly	ADV
ct-9228	84	2	,	,	PUNCT
ct-9228	84	3	but	but	CCONJ
ct-9228	84	4	more	more	ADV
ct-9228	84	5	rigorous	rigorous	ADJ
ct-9228	84	6	is	be	AUX
ct-9228	84	7	the	the	DET
ct-9228	84	8	analysis	analysis	NOUN
ct-9228	84	9	of	of	ADP
ct-9228	84	10	the	the	DET
ct-9228	84	11	protein	protein	NOUN
ct-9228	84	12	profile	profile	NOUN
ct-9228	84	13	,	,	PUNCT
ct-9228	84	14	demonstrating	demonstrate	VERB
ct-9228	84	15	that	that	SCONJ
ct-9228	84	16	the	the	DET
ct-9228	84	17	cell	cell	NOUN
ct-9228	84	18	not	not	PART
ct-9228	84	19	only	only	ADV
ct-9228	84	20	generated	generate	VERB
ct-9228	84	21	appropriate	appropriate	ADJ
ct-9228	84	22	mrna	mrna	NOUN
ct-9228	84	23	,	,	PUNCT
ct-9228	84	24	but	but	CCONJ
ct-9228	84	25	translated	translate	VERB
ct-9228	84	26	that	that	DET
ct-9228	84	27	mrna	mrna	NOUN
ct-9228	84	28	to	to	ADP
ct-9228	84	29	the	the	DET
ct-9228	84	30	appropriate	appropriate	ADJ
ct-9228	84	31	protein	protein	NOUN
ct-9228	84	32	profile	profile	NOUN
ct-9228	84	33	.	.	PUNCT
ct-9228	85	1	however	however	ADV
ct-9228	85	2	,	,	PUNCT
ct-9228	85	3	as	as	SCONJ
ct-9228	85	4	previously	previously	ADV
ct-9228	85	5	mentioned	mention	VERB
ct-9228	85	6	,	,	PUNCT
ct-9228	85	7	functional	functional	ADJ
ct-9228	85	8	testing	testing	NOUN
ct-9228	85	9	is	be	AUX
ct-9228	85	10	the	the	DET
ct-9228	85	11	gold	gold	ADJ
ct-9228	85	12	standard	standard	NOUN
ct-9228	85	13	for	for	ADP
ct-9228	85	14	confirmation	confirmation	NOUN
ct-9228	85	15	of	of	ADP
ct-9228	85	16	cell	cell	NOUN
ct-9228	85	17	specification	specification	NOUN
ct-9228	85	18	,	,	PUNCT
ct-9228	85	19	demonstrating	demonstrate	VERB
ct-9228	85	20	that	that	SCONJ
ct-9228	85	21	the	the	DET
ct-9228	85	22	cell	cell	NOUN
ct-9228	85	23	functions	function	NOUN
ct-9228	85	24	as	as	ADP
ct-9228	85	25	and	and	CCONJ
ct-9228	85	26	,	,	PUNCT
ct-9228	85	27	ultimately	ultimately	ADV
ct-9228	85	28	,	,	PUNCT
ct-9228	85	29	can	can	AUX
ct-9228	85	30	integrate	integrate	VERB
ct-9228	85	31	into	into	ADP
ct-9228	85	32	the	the	DET
ct-9228	85	33	desired	desire	VERB
ct-9228	85	34	tissue.30	tissue.30	PROPN
ct-9228	85	35	conclusion	conclusion	NOUN
ct-9228	85	36	stem	stem	NOUN
ct-9228	85	37	cells	cell	NOUN
ct-9228	85	38	are	be	AUX
ct-9228	85	39	fascinating	fascinating	ADJ
ct-9228	85	40	with	with	ADP
ct-9228	85	41	a	a	DET
ct-9228	85	42	solid	solid	ADJ
ct-9228	85	43	history	history	NOUN
ct-9228	85	44	of	of	ADP
ct-9228	85	45	providing	provide	VERB
ct-9228	85	46	clinical	clinical	ADJ
ct-9228	85	47	benefit	benefit	NOUN
ct-9228	85	48	and	and	CCONJ
ct-9228	85	49	broad	broad	ADJ
ct-9228	85	50	applicability	applicability	NOUN
ct-9228	85	51	for	for	ADP
ct-9228	85	52	new	new	ADJ
ct-9228	85	53	uses	use	NOUN
ct-9228	85	54	as	as	ADP
ct-9228	85	55	our	our	PRON
ct-9228	85	56	understanding	understanding	NOUN
ct-9228	85	57	of	of	ADP
ct-9228	85	58	how	how	SCONJ
ct-9228	85	59	to	to	PART
ct-9228	85	60	harness	harness	VERB
ct-9228	85	61	their	their	PRON
ct-9228	85	62	potential	potential	ADJ
ct-9228	85	63	grows	grow	NOUN
ct-9228	85	64	.	.	PUNCT
ct-9228	86	1	the	the	DET
ct-9228	86	2	applications	application	NOUN
ct-9228	86	3	continue	continue	VERB
ct-9228	86	4	to	to	PART
ct-9228	86	5	expand	expand	VERB
ct-9228	86	6	as	as	SCONJ
ct-9228	86	7	we	we	PRON
ct-9228	86	8	learn	learn	VERB
ct-9228	86	9	how	how	SCONJ
ct-9228	86	10	to	to	PART
ct-9228	86	11	tap	tap	VERB
ct-9228	86	12	into	into	ADP
ct-9228	86	13	the	the	DET
ct-9228	86	14	potential	potential	NOUN
ct-9228	86	15	of	of	ADP
ct-9228	86	16	all	all	DET
ct-9228	86	17	that	that	PRON
ct-9228	86	18	stem	stem	NOUN
ct-9228	86	19	cells	cell	NOUN
ct-9228	86	20	have	have	VERB
ct-9228	86	21	to	to	PART
ct-9228	86	22	offer	offer	VERB
ct-9228	86	23	.	.	PUNCT
ct-9228	87	1	conflict	conflict	NOUN
ct-9228	87	2	of	of	ADP
ct-9228	87	3	interest	interest	NOUN
ct-9228	87	4	there	there	PRON
ct-9228	87	5	are	be	VERB
ct-9228	87	6	no	no	DET
ct-9228	87	7	conflicts	conflict	NOUN
ct-9228	87	8	of	of	ADP
ct-9228	87	9	interest	interest	NOUN
ct-9228	87	10	to	to	PART
ct-9228	87	11	declare	declare	VERB
ct-9228	87	12	.	.	PUNCT
ct-9228	88	1	clinical	clinical	ADJ
ct-9228	88	2	theriogenology	theriogenology	NOUN
ct-9228	88	3	•	•	NOUN
ct-9228	88	4	volume	volume	NOUN
ct-9228	88	5	12	12	NUM
ct-9228	88	6	number	number	NOUN
ct-9228	88	7	3	3	NUM
ct-9228	88	8	•	•	NOUN
ct-9228	88	9	september	september	PROPN
ct-9228	88	10	2020186	2020186	NUM
ct-9228	88	11	references	reference	NOUN
ct-9228	88	12	1	1	NUM
ct-9228	88	13	.	.	PUNCT
ct-9228	89	1	evans	evans	PROPN
ct-9228	89	2	mj	mj	PROPN
ct-9228	89	3	,	,	PUNCT
ct-9228	89	4	kaufman	kaufman	PROPN
ct-9228	89	5	mh	mh	PROPN
ct-9228	89	6	:	:	PUNCT
ct-9228	89	7	establishment	establishment	NOUN
ct-9228	89	8	in	in	ADP
ct-9228	89	9	culture	culture	NOUN
ct-9228	89	10	of	of	ADP
ct-9228	89	11	pluripotential	pluripotential	ADJ
ct-9228	89	12	cells	cell	NOUN
ct-9228	89	13	from	from	ADP
ct-9228	89	14	mouse	mouse	NOUN
ct-9228	89	15	embryos	embryo	NOUN
ct-9228	89	16	.	.	PUNCT
ct-9228	90	1	nature	nature	NOUN
ct-9228	90	2	1981;292	1981;292	NUM
ct-9228	90	3	:	:	PUNCT
ct-9228	90	4	154	154	NUM
ct-9228	90	5	-	-	SYM
ct-9228	90	6	156	156	NUM
ct-9228	90	7	.	.	PUNCT
ct-9228	90	8	2	2	NUM
ct-9228	90	9	.	.	X
ct-9228	90	10	simerly	simerly	PROPN
ct-9228	90	11	cr	cr	PROPN
ct-9228	90	12	,	,	PUNCT
ct-9228	90	13	navara	navara	PROPN
ct-9228	90	14	cs	cs	PROPN
ct-9228	90	15	,	,	PUNCT
ct-9228	90	16	castro	castro	PROPN
ct-9228	90	17	ca	can	AUX
ct-9228	90	18	,	,	PUNCT
ct-9228	90	19	et	et	PROPN
ct-9228	90	20	al	al	PROPN
ct-9228	90	21	:	:	PUNCT
ct-9228	90	22	establishment	establishment	NOUN
ct-9228	90	23	and	and	CCONJ
ct-9228	90	24	characterization	characterization	NOUN
ct-9228	90	25	of	of	ADP
ct-9228	90	26	baboon	baboon	NOUN
ct-9228	90	27	embryonic	embryonic	ADJ
ct-9228	90	28	stem	stem	NOUN
ct-9228	90	29	cell	cell	NOUN
ct-9228	90	30	lines	line	NOUN
ct-9228	90	31	:	:	PUNCT
ct-9228	90	32	an	an	DET
ct-9228	90	33	old	old	ADJ
ct-9228	90	34	world	world	NOUN
ct-9228	90	35	primate	primate	NOUN
ct-9228	90	36	model	model	NOUN
ct-9228	90	37	for	for	ADP
ct-9228	90	38	regeneration	regeneration	NOUN
ct-9228	90	39	and	and	CCONJ
ct-9228	90	40	transplantation	transplantation	NOUN
ct-9228	90	41	research	research	NOUN
ct-9228	90	42	.	.	PUNCT
ct-9228	91	1	stem	stem	NOUN
ct-9228	91	2	cell	cell	NOUN
ct-9228	91	3	res	re	NOUN
ct-9228	91	4	2009	2009	NUM
ct-9228	91	5	.	.	PUNCT
ct-9228	92	1	doi	doi	NOUN
ct-9228	92	2	:	:	PUNCT
ct-9228	92	3	s18735061(09)00022	s18735061(09)00022	VERB
ct-9228	92	4	-	-	PUNCT
ct-9228	92	5	1	1	NUM
ct-9228	92	6	[	[	X
ct-9228	92	7	pii]10.1016	pii]10.1016	NUM
ct-9228	92	8	/	/	SYM
ct-9228	92	9	j.scr.2009.02.004	j.scr.2009.02.004	NOUN
ct-9228	92	10	.	.	PUNCT
ct-9228	93	1	pubmed	pubmed	PROPN
ct-9228	93	2	pmid	pmid	PROPN
ct-9228	93	3	:	:	PUNCT
ct-9228	93	4	19393591	19393591	NUM
ct-9228	93	5	.	.	PUNCT
ct-9228	94	1	3	3	X
ct-9228	94	2	.	.	X
ct-9228	94	3	thomson	thomson	PROPN
ct-9228	94	4	ja	ja	PROPN
ct-9228	94	5	,	,	PUNCT
ct-9228	94	6	itskovitz	itskovitz	PROPN
ct-9228	94	7	-	-	PUNCT
ct-9228	94	8	eldor	eldor	NOUN
ct-9228	94	9	j	j	PROPN
ct-9228	94	10	,	,	PUNCT
ct-9228	94	11	shapiro	shapiro	PROPN
ct-9228	94	12	ss	ss	PROPN
ct-9228	94	13	,	,	PUNCT
ct-9228	94	14	et	et	PROPN
ct-9228	94	15	al	al	PROPN
ct-9228	94	16	:	:	PUNCT
ct-9228	94	17	embryonic	embryonic	ADJ
ct-9228	94	18	stem	stem	NOUN
ct-9228	94	19	cell	cell	NOUN
ct-9228	94	20	lines	line	NOUN
ct-9228	94	21	derived	derive	VERB
ct-9228	94	22	from	from	ADP
ct-9228	94	23	human	human	ADJ
ct-9228	94	24	blastocysts	blastocyst	NOUN
ct-9228	94	25	.	.	PUNCT
ct-9228	95	1	science	science	NOUN
ct-9228	95	2	1998;282:1145	1998;282:1145	NUM
ct-9228	95	3	-	-	SYM
ct-9228	95	4	1147	1147	NUM
ct-9228	95	5	.	.	PUNCT
ct-9228	96	1	pubmed	pubmed	PROPN
ct-9228	96	2	pmid	pmid	PROPN
ct-9228	96	3	:	:	PUNCT
ct-9228	96	4	9804556	9804556	NUM
ct-9228	96	5	.	.	PUNCT
ct-9228	97	1	4	4	X
ct-9228	97	2	.	.	X
ct-9228	97	3	cibelli	cibelli	PROPN
ct-9228	97	4	jb	jb	PROPN
ct-9228	97	5	,	,	PUNCT
ct-9228	97	6	stice	stice	PROPN
ct-9228	97	7	sl	sl	PROPN
ct-9228	97	8	,	,	PUNCT
ct-9228	97	9	golueke	golueke	PROPN
ct-9228	97	10	pj	pj	PROPN
ct-9228	97	11	,	,	PUNCT
ct-9228	97	12	et	et	PROPN
ct-9228	97	13	al	al	PROPN
ct-9228	97	14	:	:	PUNCT
ct-9228	97	15	transgenic	transgenic	NOUN
ct-9228	97	16	bovine	bovine	NOUN
ct-9228	97	17	chimeric	chimeric	ADJ
ct-9228	97	18	offspring	offspring	NOUN
ct-9228	97	19	produced	produce	VERB
ct-9228	97	20	from	from	ADP
ct-9228	97	21	somatic	somatic	ADJ
ct-9228	97	22	cell	cell	NOUN
ct-9228	97	23	-	-	PUNCT
ct-9228	97	24	derived	derive	VERB
ct-9228	97	25	stemlike	stemlike	ADJ
ct-9228	97	26	cells	cell	NOUN
ct-9228	97	27	.	.	PUNCT
ct-9228	98	1	nat	nat	PROPN
ct-9228	98	2	biotechnol	biotechnol	PROPN
ct-9228	98	3	1998;16:642	1998;16:642	NUM
ct-9228	98	4	-	-	SYM
ct-9228	98	5	646	646	NUM
ct-9228	98	6	.	.	PUNCT
ct-9228	99	1	pubmed	pubmed	PROPN
ct-9228	99	2	pmid	pmid	PROPN
ct-9228	99	3	:	:	PUNCT
ct-9228	99	4	9661197	9661197	NUM
ct-9228	99	5	.	.	PUNCT
ct-9228	100	1	5	5	NUM
ct-9228	100	2	.	.	PUNCT
ct-9228	101	1	saito	saito	PROPN
ct-9228	101	2	s	s	PROPN
ct-9228	101	3	,	,	PUNCT
ct-9228	101	4	sawai	sawai	PROPN
ct-9228	101	5	k	k	PROPN
ct-9228	101	6	,	,	PUNCT
ct-9228	101	7	ugai	ugai	PROPN
ct-9228	101	8	h	h	NOUN
ct-9228	101	9	,	,	PUNCT
ct-9228	101	10	et	et	PROPN
ct-9228	101	11	al	al	PROPN
ct-9228	101	12	:	:	PUNCT
ct-9228	101	13	generation	generation	NOUN
ct-9228	101	14	of	of	ADP
ct-9228	101	15	cloned	cloned	ADJ
ct-9228	101	16	calves	calf	NOUN
ct-9228	101	17	and	and	CCONJ
ct-9228	101	18	transgenic	transgenic	NOUN
ct-9228	101	19	chimeric	chimeric	ADJ
ct-9228	101	20	embryos	embryo	NOUN
ct-9228	101	21	from	from	ADP
ct-9228	101	22	bovine	bovine	ADJ
ct-9228	101	23	embryonic	embryonic	ADJ
ct-9228	101	24	stem	stem	NOUN
ct-9228	101	25	-	-	PUNCT
ct-9228	101	26	like	like	ADJ
ct-9228	101	27	cells	cell	NOUN
ct-9228	101	28	.	.	PUNCT
ct-9228	102	1	biochem	biochem	PROPN
ct-9228	102	2	biophys	biophys	PROPN
ct-9228	102	3	res	res	PROPN
ct-9228	102	4	commun	commun	PROPN
ct-9228	102	5	2003;309:104	2003;309:104	PROPN
ct-9228	102	6	-	-	SYM
ct-9228	102	7	113	113	NUM
ct-9228	102	8	.	.	PUNCT
ct-9228	103	1	pubmed	pubmed	PROPN
ct-9228	103	2	pmid	pmid	PROPN
ct-9228	103	3	:	:	PUNCT
ct-9228	103	4	12943670	12943670	NUM
ct-9228	103	5	.	.	PUNCT
ct-9228	104	1	6	6	NUM
ct-9228	104	2	.	.	X
ct-9228	104	3	mitalipova	mitalipova	PROPN
ct-9228	104	4	m	m	PROPN
ct-9228	104	5	,	,	PUNCT
ct-9228	104	6	calhoun	calhoun	PROPN
ct-9228	104	7	j	j	PROPN
ct-9228	104	8	,	,	PUNCT
ct-9228	104	9	shin	shin	PROPN
ct-9228	104	10	s	s	PROPN
ct-9228	104	11	,	,	PUNCT
ct-9228	104	12	et	et	PROPN
ct-9228	104	13	al	al	PROPN
ct-9228	104	14	:	:	PUNCT
ct-9228	104	15	human	human	ADJ
ct-9228	104	16	embryonic	embryonic	ADJ
ct-9228	104	17	stem	stem	NOUN
ct-9228	104	18	cell	cell	NOUN
ct-9228	104	19	lines	line	NOUN
ct-9228	104	20	derived	derive	VERB
ct-9228	104	21	from	from	ADP
ct-9228	104	22	discarded	discard	VERB
ct-9228	104	23	embryos	embryo	NOUN
ct-9228	104	24	.	.	PUNCT
ct-9228	105	1	stem	stem	NOUN
ct-9228	105	2	cells	cell	NOUN
ct-9228	105	3	2003;21:521	2003;21:521	NUM
ct-9228	105	4	-	-	SYM
ct-9228	105	5	526	526	NUM
ct-9228	105	6	.	.	PUNCT
ct-9228	106	1	epub	epub	PROPN
ct-9228	106	2	2003/09/12	2003/09/12	NUM
ct-9228	106	3	.	.	PUNCT
ct-9228	107	1	pubmed	pubmed	PROPN
ct-9228	107	2	pmid	pmid	PROPN
ct-9228	107	3	:	:	PUNCT
ct-9228	107	4	12968106	12968106	NUM
ct-9228	107	5	.	.	PUNCT
ct-9228	108	1	7	7	X
ct-9228	108	2	.	.	X
ct-9228	108	3	ohkoshi	ohkoshi	PROPN
ct-9228	108	4	k	k	PROPN
ct-9228	108	5	,	,	PUNCT
ct-9228	108	6	takahashi	takahashi	PROPN
ct-9228	108	7	s	s	PROPN
ct-9228	108	8	,	,	PUNCT
ct-9228	108	9	koyama	koyama	PROPN
ct-9228	108	10	s	s	PART
ct-9228	108	11	,	,	PUNCT
ct-9228	108	12	et	et	PROPN
ct-9228	108	13	al	al	PROPN
ct-9228	108	14	:	:	PUNCT
ct-9228	108	15	in	in	ADP
ct-9228	108	16	vitro	vitro	X
ct-9228	108	17	oocyte	oocyte	ADJ
ct-9228	108	18	culture	culture	NOUN
ct-9228	108	19	and	and	CCONJ
ct-9228	108	20	somatic	somatic	ADJ
ct-9228	108	21	cell	cell	NOUN
ct-9228	108	22	nuclear	nuclear	ADJ
ct-9228	108	23	transfer	transfer	NOUN
ct-9228	108	24	used	use	VERB
ct-9228	108	25	to	to	PART
ct-9228	108	26	produce	produce	VERB
ct-9228	108	27	a	a	DET
ct-9228	108	28	l	l	NOUN
ct-9228	108	29	live	live	ADV
ct-9228	108	30	-	-	PUNCT
ct-9228	108	31	born	bear	VERB
ct-9228	108	32	cloned	cloned	ADJ
ct-9228	108	33	goat	goat	NOUN
ct-9228	108	34	.	.	PUNCT
ct-9228	109	1	cloning	cloning	NOUN
ct-9228	109	2	stem	stem	NOUN
ct-9228	109	3	cells	cell	NOUN
ct-9228	109	4	2003;5:109	2003;5:109	NUM
ct-9228	109	5	-	-	SYM
ct-9228	109	6	115	115	NUM
ct-9228	109	7	.	.	PUNCT
ct-9228	110	1	pubmed	pubmed	PROPN
ct-9228	110	2	pmid	pmid	PROPN
ct-9228	110	3	:	:	PUNCT
ct-9228	110	4	12930622	12930622	NUM
ct-9228	110	5	.	.	PUNCT
ct-9228	111	1	8	8	X
ct-9228	111	2	.	.	PUNCT
ct-9228	112	1	hyun	hyun	PROPN
ct-9228	112	2	s	s	PROPN
ct-9228	112	3	,	,	PUNCT
ct-9228	112	4	lee	lee	PROPN
ct-9228	112	5	g	g	PROPN
ct-9228	112	6	,	,	PUNCT
ct-9228	112	7	kim	kim	PROPN
ct-9228	112	8	d	d	PROPN
ct-9228	112	9	,	,	PUNCT
ct-9228	112	10	et	et	PROPN
ct-9228	112	11	al	al	PROPN
ct-9228	112	12	:	:	PUNCT
ct-9228	112	13	production	production	NOUN
ct-9228	112	14	of	of	ADP
ct-9228	112	15	nuclear	nuclear	ADJ
ct-9228	112	16	transfer	transfer	NOUN
ct-9228	112	17	-	-	PUNCT
ct-9228	112	18	derived	derive	VERB
ct-9228	112	19	piglets	piglet	NOUN
ct-9228	112	20	using	use	VERB
ct-9228	112	21	porcine	porcine	NOUN
ct-9228	112	22	fetal	fetal	ADJ
ct-9228	112	23	fibroblasts	fibroblast	NOUN
ct-9228	112	24	transfected	transfecte	VERB
ct-9228	112	25	with	with	ADP
ct-9228	112	26	the	the	DET
ct-9228	112	27	enhanced	enhance	VERB
ct-9228	112	28	green	green	ADJ
ct-9228	112	29	fluorescent	fluorescent	ADJ
ct-9228	112	30	protein	protein	NOUN
ct-9228	112	31	.	.	PUNCT
ct-9228	113	1	biol	biol	PROPN
ct-9228	113	2	reprod	reprod	NOUN
ct-9228	113	3	2003;69:1060	2003;69:1060	PROPN
ct-9228	113	4	-	-	SYM
ct-9228	113	5	1068	1068	NUM
ct-9228	113	6	.	.	PUNCT
ct-9228	114	1	pubmed	pubmed	PROPN
ct-9228	114	2	pmid	pmid	PROPN
ct-9228	114	3	:	:	PUNCT
ct-9228	114	4	12773429	12773429	NUM
ct-9228	114	5	.	.	PUNCT
ct-9228	115	1	9	9	X
ct-9228	115	2	.	.	X
ct-9228	115	3	simerly	simerly	ADV
ct-9228	115	4	c	c	PROPN
ct-9228	115	5	,	,	PUNCT
ct-9228	115	6	navara	navara	PROPN
ct-9228	115	7	c	c	PROPN
ct-9228	115	8	,	,	PUNCT
ct-9228	115	9	hyun	hyun	PROPN
ct-9228	115	10	sh	sh	PROPN
ct-9228	115	11	,	,	PUNCT
ct-9228	115	12	et	et	PROPN
ct-9228	115	13	al	al	PROPN
ct-9228	115	14	:	:	PUNCT
ct-9228	115	15	embryogenesis	embryogenesis	NOUN
ct-9228	115	16	and	and	CCONJ
ct-9228	115	17	blastocyst	blastocyst	NOUN
ct-9228	115	18	development	development	NOUN
ct-9228	115	19	after	after	ADP
ct-9228	115	20	somatic	somatic	ADJ
ct-9228	115	21	cell	cell	NOUN
ct-9228	115	22	nuclear	nuclear	ADJ
ct-9228	115	23	transfer	transfer	NOUN
ct-9228	115	24	in	in	ADP
ct-9228	115	25	nonhuman	nonhuman	ADJ
ct-9228	115	26	primates	primate	NOUN
ct-9228	115	27	:	:	PUNCT
ct-9228	115	28	overcoming	overcome	VERB
ct-9228	115	29	defects	defect	NOUN
ct-9228	115	30	caused	cause	VERB
ct-9228	115	31	by	by	ADP
ct-9228	115	32	meiotic	meiotic	ADJ
ct-9228	115	33	spindle	spindle	NOUN
ct-9228	115	34	extraction	extraction	NOUN
ct-9228	115	35	.	.	PUNCT
ct-9228	116	1	dev	dev	PROPN
ct-9228	116	2	biol	biol	PROPN
ct-9228	116	3	2004;276:237	2004;276:237	NUM
ct-9228	116	4	-	-	SYM
ct-9228	116	5	252	252	NUM
ct-9228	116	6	.	.	PUNCT
ct-9228	117	1	pubmed	pubmed	PROPN
ct-9228	117	2	pmid	pmid	PROPN
ct-9228	117	3	:	:	PUNCT
ct-9228	117	4	15581862	15581862	NUM
ct-9228	117	5	.	.	PUNCT
ct-9228	118	1	10	10	NUM
ct-9228	118	2	.	.	PUNCT
ct-9228	119	1	mitalipov	mitalipov	PROPN
ct-9228	119	2	sm	sm	PROPN
ct-9228	119	3	,	,	PUNCT
ct-9228	119	4	wolf	wolf	PROPN
ct-9228	119	5	dp	dp	PROPN
ct-9228	119	6	:	:	PUNCT
ct-9228	119	7	nuclear	nuclear	ADJ
ct-9228	119	8	transfer	transfer	NOUN
ct-9228	119	9	in	in	ADP
ct-9228	119	10	nonhuman	nonhuman	ADJ
ct-9228	119	11	primates	primate	NOUN
ct-9228	119	12	.	.	PUNCT
ct-9228	120	1	methods	method	NOUN
ct-9228	120	2	mol	mol	ADP
ct-9228	120	3	biol	biol	PROPN
ct-9228	120	4	2006;348:151	2006;348:151	NUM
ct-9228	120	5	-	-	SYM
ct-9228	120	6	168	168	NUM
ct-9228	120	7	.	.	PUNCT
ct-9228	121	1	pubmed	pubmed	PROPN
ct-9228	121	2	pmid	pmid	PROPN
ct-9228	121	3	:	:	PUNCT
ct-9228	121	4	16988378	16988378	NUM
ct-9228	121	5	.	.	PUNCT
ct-9228	122	1	11	11	NUM
ct-9228	122	2	.	.	X
ct-9228	123	1	thongphakdee	thongphakdee	PROPN
ct-9228	123	2	a	a	PROPN
ct-9228	123	3	,	,	PUNCT
ct-9228	123	4	numchaisrika	numchaisrika	PROPN
ct-9228	123	5	p	p	NOUN
ct-9228	123	6	,	,	PUNCT
ct-9228	123	7	omsongkram	omsongkram	NOUN
ct-9228	123	8	s	s	PART
ct-9228	123	9	,	,	PUNCT
ct-9228	123	10	et	et	PROPN
ct-9228	123	11	al	al	PROPN
ct-9228	123	12	:	:	PUNCT
ct-9228	123	13	in	in	ADP
ct-9228	123	14	vitro	vitro	X
ct-9228	123	15	development	development	NOUN
ct-9228	123	16	of	of	ADP
ct-9228	123	17	marbled	marbled	ADJ
ct-9228	123	18	cat	cat	NOUN
ct-9228	123	19	embryos	embryo	NOUN
ct-9228	123	20	derived	derive	VERB
ct-9228	123	21	from	from	ADP
ct-9228	123	22	interspecies	interspecie	NOUN
ct-9228	123	23	somatic	somatic	ADJ
ct-9228	123	24	cell	cell	NOUN
ct-9228	123	25	nuclear	nuclear	ADJ
ct-9228	123	26	transfer	transfer	NOUN
ct-9228	123	27	.	.	PUNCT
ct-9228	124	1	reprod	reprod	PROPN
ct-9228	124	2	domest	domest	PROPN
ct-9228	124	3	anim	anim	PROPN
ct-9228	124	4	2006;41:219	2006;41:219	PROPN
ct-9228	124	5	-	-	SYM
ct-9228	124	6	226	226	NUM
ct-9228	124	7	.	.	PUNCT
ct-9228	125	1	pubmed	pubmed	PROPN
ct-9228	125	2	pmid	pmid	PROPN
ct-9228	125	3	:	:	PUNCT
ct-9228	125	4	16689885	16689885	NUM
ct-9228	125	5	.	.	PUNCT
ct-9228	126	1	12	12	NUM
ct-9228	126	2	.	.	PUNCT
ct-9228	127	1	campbell	campbell	PROPN
ct-9228	127	2	kh	kh	PROPN
ct-9228	127	3	,	,	PUNCT
ct-9228	127	4	mcwhir	mcwhir	PROPN
ct-9228	127	5	j	j	PROPN
ct-9228	127	6	,	,	PUNCT
ct-9228	127	7	ritchie	ritchie	PROPN
ct-9228	127	8	wa	wa	PROPN
ct-9228	127	9	,	,	PUNCT
ct-9228	127	10	et	et	PROPN
ct-9228	127	11	al	al	PROPN
ct-9228	127	12	:	:	PUNCT
ct-9228	127	13	sheep	sheep	NOUN
ct-9228	127	14	cloned	clone	VERB
ct-9228	127	15	by	by	ADP
ct-9228	127	16	nuclear	nuclear	ADJ
ct-9228	127	17	transfer	transfer	NOUN
ct-9228	127	18	from	from	ADP
ct-9228	127	19	a	a	DET
ct-9228	127	20	cultured	cultured	ADJ
ct-9228	127	21	cell	cell	NOUN
ct-9228	127	22	line	line	NOUN
ct-9228	127	23	.	.	PUNCT
ct-9228	128	1	nature	nature	NOUN
ct-9228	128	2	1996;380:64	1996;380:64	NUM
ct-9228	128	3	-	-	SYM
ct-9228	128	4	66	66	NUM
ct-9228	128	5	.	.	PUNCT
ct-9228	129	1	pubmed	pubmed	PROPN
ct-9228	129	2	pmid	pmid	PROPN
ct-9228	129	3	:	:	PUNCT
ct-9228	129	4	8598906	8598906	NUM
ct-9228	129	5	.	.	PUNCT
ct-9228	130	1	13	13	NUM
ct-9228	130	2	.	.	X
ct-9228	131	1	rao	rao	PROPN
ct-9228	131	2	ms	ms	PROPN
ct-9228	131	3	:	:	PUNCT
ct-9228	131	4	are	be	AUX
ct-9228	131	5	there	there	PRON
ct-9228	131	6	morally	morally	ADV
ct-9228	131	7	acceptable	acceptable	ADJ
ct-9228	131	8	alternatives	alternative	NOUN
ct-9228	131	9	to	to	ADP
ct-9228	131	10	blastocyst	blastocyst	NOUN
ct-9228	131	11	derived	derive	VERB
ct-9228	131	12	esc	esc	NOUN
ct-9228	131	13	?	?	PUNCT
ct-9228	132	1	j	j	PROPN
ct-9228	132	2	cell	cell	NOUN
ct-9228	132	3	biochem	biochem	NOUN
ct-9228	132	4	2006;98:1054	2006;98:1054	NUM
ct-9228	132	5	-	-	SYM
ct-9228	132	6	1061	1061	NUM
ct-9228	132	7	.	.	PUNCT
ct-9228	133	1	pubmed	pubmed	PROPN
ct-9228	133	2	pmid	pmid	PROPN
ct-9228	133	3	:	:	PUNCT
ct-9228	133	4	16598787	16598787	NUM
ct-9228	133	5	.	.	PUNCT
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ct-9228	134	2	.	.	PUNCT
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ct-9228	135	14	of	of	ADP
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ct-9228	136	3	.	.	PUNCT
ct-9228	137	1	epub	epub	PROPN
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ct-9228	137	3	.	.	PUNCT
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ct-9228	139	5	.	.	PUNCT
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ct-9228	140	2	.	.	PUNCT
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ct-9228	141	3	:	:	PUNCT
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ct-9228	141	14	transcription	transcription	NOUN
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ct-9228	142	8	.	.	PUNCT
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ct-9228	144	7	.	.	PUNCT
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ct-9228	145	3	:	:	PUNCT
ct-9228	145	4	18181945	18181945	NUM
ct-9228	145	5	.	.	PUNCT
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ct-9228	146	2	.	.	PUNCT
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ct-9228	147	18	;	;	PUNCT
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ct-9228	148	1	[	[	X
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ct-9228	148	5	]	]	PUNCT
ct-9228	148	6	.	.	PUNCT
ct-9228	149	1	lt0071:[available	lt0071:[available	ADJ
ct-9228	149	2	from	from	ADP
ct-9228	149	3	:	:	PUNCT
ct-9228	149	4	https://jackson.jax.org/rs/444-buh-304/images/whitepaper_crispr.pdf	https://jackson.jax.org/rs/444-buh-304/images/whitepaper_crispr.pdf	NOUN
ct-9228	149	5	.	.	PUNCT
ct-9228	150	1	17	17	NUM
ct-9228	150	2	.	.	PUNCT
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ct-9228	150	25	human	human	ADJ
ct-9228	150	26	ipscs	ipsc	NOUN
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ct-9228	151	9	:	:	PUNCT
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ct-9228	153	1	doi	doi	NOUN
ct-9228	153	2	:	:	PUNCT
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ct-9228	153	9	:	:	PUNCT
ct-9228	153	10	29203658	29203658	NUM
ct-9228	153	11	;	;	PUNCT
ct-9228	153	12	pubmed	pubmed	PROPN
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ct-9228	153	15	:	:	PUNCT
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ct-9228	153	17	.	.	PUNCT
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ct-9228	154	2	.	.	PUNCT
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ct-9228	155	8	control	control	NOUN
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ct-9228	155	11	application	application	NOUN
ct-9228	155	12	of	of	ADP
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ct-9228	155	14	pluripotent	pluripotent	ADJ
ct-9228	155	15	stem	stem	NOUN
ct-9228	155	16	cells	cell	NOUN
ct-9228	155	17	.	.	PUNCT
ct-9228	156	1	curr	curr	PROPN
ct-9228	156	2	opin	opin	PROPN
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ct-9228	156	6	-	-	SYM
ct-9228	156	7	169	169	NUM
ct-9228	156	8	.	.	PUNCT
ct-9228	157	1	epub	epub	PROPN
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ct-9228	157	3	.	.	PUNCT
ct-9228	158	1	doi	doi	NOUN
ct-9228	158	2	:	:	PUNCT
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ct-9228	159	1	pubmed	pubmed	PROPN
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ct-9228	159	4	28823985	28823985	NUM
ct-9228	159	5	.	.	PUNCT
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ct-9228	160	2	.	.	PUNCT
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ct-9228	160	14	:	:	PUNCT
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ct-9228	162	2	-	-	SYM
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ct-9228	163	3	:	:	PUNCT
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ct-9228	163	5	.	.	PUNCT
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ct-9228	164	2	.	.	PUNCT
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ct-9228	168	6	[	[	X
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ct-9228	168	10	-	-	PUNCT
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ct-9228	168	12	.	.	PUNCT
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ct-9228	169	3	:	:	PUNCT
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ct-9228	169	5	.	.	PUNCT
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ct-9228	173	10	-	-	SYM
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ct-9228	174	3	:	:	PUNCT
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ct-9228	176	12	:	:	PUNCT
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ct-9228	180	10	-	-	PUNCT
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ct-9228	182	15	of	of	ADP
ct-9228	182	16	mouse	mouse	NOUN
ct-9228	182	17	hematopoietic	hematopoietic	ADJ
ct-9228	182	18	stem	stem	NOUN
ct-9228	182	19	cells	cell	NOUN
ct-9228	182	20	.	.	PUNCT
ct-9228	183	1	science	science	NOUN
ct-9228	183	2	1988;241:58	1988;241:58	NUM
ct-9228	183	3	-	-	SYM
ct-9228	183	4	62	62	NUM
ct-9228	183	5	.	.	PUNCT
ct-9228	184	1	epub	epub	NOUN
ct-9228	184	2	1988/07/01	1988/07/01	NUM
ct-9228	184	3	.	.	PUNCT
ct-9228	185	1	doi	doi	NOUN
ct-9228	185	2	:	:	PUNCT
ct-9228	185	3	10.1126	10.1126	NUM
ct-9228	185	4	/	/	SYM
ct-9228	185	5	science.2898810	science.2898810	PROPN
ct-9228	185	6	.	.	PUNCT
ct-9228	185	7	pubmed	pubmed	PROPN
ct-9228	185	8	pmid	pmid	PROPN
ct-9228	185	9	:	:	PUNCT
ct-9228	185	10	2898810	2898810	NUM
ct-9228	185	11	.	.	PUNCT
ct-9228	186	1	24	24	NUM
ct-9228	186	2	.	.	PUNCT
ct-9228	187	1	krabbe	krabbe	PROPN
ct-9228	187	2	c	c	PROPN
ct-9228	187	3	,	,	PUNCT
ct-9228	187	4	zimmer	zimmer	PROPN
ct-9228	187	5	j	j	PROPN
ct-9228	187	6	,	,	PUNCT
ct-9228	187	7	meyer	meyer	PROPN
ct-9228	187	8	m	m	PROPN
ct-9228	187	9	:	:	PUNCT
ct-9228	187	10	neural	neural	ADJ
ct-9228	187	11	transdifferentiation	transdifferentiation	NOUN
ct-9228	187	12	of	of	ADP
ct-9228	187	13	mesenchymal	mesenchymal	ADJ
ct-9228	187	14	stem	stem	NOUN
ct-9228	187	15	cells	cell	NOUN
ct-9228	187	16	--	--	PUNCT
ct-9228	187	17	a	a	DET
ct-9228	187	18	critical	critical	ADJ
ct-9228	187	19	review	review	NOUN
ct-9228	187	20	.	.	PUNCT
ct-9228	188	1	apmis	apmis	PROPN
ct-9228	188	2	.	.	PUNCT
ct-9228	189	1	2005;113:831	2005;113:831	NUM
ct-9228	189	2	-	-	SYM
ct-9228	189	3	844	844	NUM
ct-9228	189	4	.	.	PUNCT
ct-9228	190	1	epub	epub	PROPN
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ct-9228	190	3	.	.	PUNCT
ct-9228	191	1	doi	doi	NOUN
ct-9228	191	2	:	:	PUNCT
ct-9228	191	3	10.1111	10.1111	NUM
ct-9228	191	4	/	/	SYM
ct-9228	191	5	j.1600	j.1600	PROPN
ct-9228	191	6	-	-	PUNCT
ct-9228	191	7	0463.2005.apm_3061.x	0463.2005.apm_3061.x	PROPN
ct-9228	191	8	.	.	PUNCT
ct-9228	192	1	pubmed	pubmed	PROPN
ct-9228	192	2	pmid	pmid	PROPN
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ct-9228	192	4	16480453	16480453	NUM
ct-9228	192	5	.	.	PUNCT
ct-9228	193	1	25	25	NUM
ct-9228	193	2	.	.	PUNCT
ct-9228	193	3	gnecchi	gnecchi	PROPN
ct-9228	193	4	m	m	PROPN
ct-9228	193	5	,	,	PUNCT
ct-9228	193	6	danieli	danieli	ADJ
ct-9228	193	7	p	p	NOUN
ct-9228	193	8	,	,	PUNCT
ct-9228	193	9	malpasso	malpasso	NOUN
ct-9228	193	10	g	g	NOUN
ct-9228	193	11	,	,	PUNCT
ct-9228	193	12	et	et	PROPN
ct-9228	193	13	al	al	PROPN
ct-9228	193	14	:	:	PUNCT
ct-9228	193	15	paracrine	paracrine	ADJ
ct-9228	193	16	mechanisms	mechanism	NOUN
ct-9228	193	17	of	of	ADP
ct-9228	193	18	mesenchymal	mesenchymal	NOUN
ct-9228	193	19	stem	stem	NOUN
ct-9228	193	20	cells	cell	NOUN
ct-9228	193	21	in	in	ADP
ct-9228	193	22	tissue	tissue	NOUN
ct-9228	193	23	repair	repair	NOUN
ct-9228	193	24	.	.	PUNCT
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ct-9228	194	2	mol	mol	ADP
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ct-9228	194	5	-	-	SYM
ct-9228	194	6	146	146	NUM
ct-9228	194	7	.	.	PUNCT
ct-9228	195	1	epub	epub	PROPN
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ct-9228	195	3	.	.	PUNCT
ct-9228	196	1	doi	doi	NOUN
ct-9228	196	2	:	:	PUNCT
ct-9228	196	3	10.1007/978	10.1007/978	NUM
ct-9228	196	4	-	-	SYM
ct-9228	196	5	1	1	NUM
ct-9228	196	6	-	-	PUNCT
ct-9228	196	7	4939	4939	NUM
ct-9228	196	8	-	-	PUNCT
ct-9228	196	9	3584	3584	NUM
ct-9228	196	10	-	-	PUNCT
ct-9228	196	11	0_7	0_7	NUM
ct-9228	196	12	.	.	PUNCT
ct-9228	197	1	pubmed	pubmed	PROPN
ct-9228	197	2	pmid	pmid	PROPN
ct-9228	197	3	:	:	PUNCT
ct-9228	197	4	27236669	27236669	NUM
ct-9228	197	5	.	.	PUNCT
ct-9228	198	1	26	26	NUM
ct-9228	198	2	.	.	PUNCT
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ct-9228	199	11	al	al	PROPN
ct-9228	199	12	:	:	PUNCT
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ct-9228	199	14	stem	stem	NOUN
ct-9228	199	15	cells	cell	NOUN
ct-9228	199	16	:	:	PUNCT
ct-9228	199	17	toward	toward	ADP
ct-9228	199	18	the	the	DET
ct-9228	199	19	regeneration	regeneration	NOUN
ct-9228	199	20	of	of	ADP
ct-9228	199	21	spermatogenesis	spermatogenesis	NOUN
ct-9228	199	22	.	.	PUNCT
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ct-9228	200	2	steril	steril	PROPN
ct-9228	200	3	.	.	PUNCT
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ct-9228	201	2	-	-	SYM
ct-9228	201	3	13	13	NUM
ct-9228	201	4	.	.	PUNCT
ct-9228	202	1	epub	epub	NOUN
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ct-9228	202	3	.	.	PUNCT
ct-9228	203	1	doi	doi	NOUN
ct-9228	203	2	:	:	PUNCT
ct-9228	203	3	10.1016	10.1016	NUM
ct-9228	203	4	/	/	SYM
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ct-9228	203	6	.	.	PUNCT
ct-9228	204	1	pubmed	pubmed	PROPN
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ct-9228	204	3	:	:	PUNCT
ct-9228	204	4	24314923	24314923	NUM
ct-9228	204	5	;	;	PUNCT
ct-9228	204	6	pubmed	pubmed	PROPN
ct-9228	204	7	central	central	ADJ
ct-9228	204	8	pmcid	pmcid	PROPN
ct-9228	204	9	:	:	PUNCT
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ct-9228	204	13	.	.	PUNCT
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ct-9228	205	3	,	,	PUNCT
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ct-9228	205	6	:	:	PUNCT
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ct-9228	205	9	cell	cell	NOUN
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ct-9228	205	11	in	in	ADP
ct-9228	205	12	livestock	livestock	NOUN
ct-9228	205	13	.	.	PUNCT
ct-9228	206	1	reprod	reprod	PROPN
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ct-9228	207	2	-	-	SYM
ct-9228	207	3	18	18	NUM
ct-9228	207	4	.	.	PUNCT
ct-9228	208	1	epub	epub	NOUN
ct-9228	208	2	2006/02/16	2006/02/16	NUM
ct-9228	208	3	.	.	PUNCT
ct-9228	209	1	doi	doi	NOUN
ct-9228	209	2	:	:	PUNCT
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ct-9228	209	4	/	/	SYM
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ct-9228	209	6	.	.	PUNCT
ct-9228	210	1	pubmed	pubmed	PROPN
ct-9228	210	2	pmid	pmid	PROPN
ct-9228	210	3	:	:	PUNCT
ct-9228	210	4	16478598	16478598	NUM
ct-9228	210	5	.	.	PUNCT
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ct-9228	211	3	•	•	NOUN
ct-9228	211	4	volume	volume	NOUN
ct-9228	211	5	12	12	NUM
ct-9228	211	6	number	number	NOUN
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ct-9228	211	8	•	•	NUM
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ct-9228	211	10	2020	2020	NUM
ct-9228	211	11	187	187	NUM
ct-9228	211	12	28	28	NUM
ct-9228	211	13	.	.	PUNCT
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ct-9228	212	2	cl	cl	PROPN
ct-9228	212	3	,	,	PUNCT
ct-9228	212	4	pera	pera	PROPN
ct-9228	212	5	mf	mf	VERB
ct-9228	212	6	:	:	PUNCT
ct-9228	212	7	capturing	capture	VERB
ct-9228	212	8	totipotent	totipotent	ADJ
ct-9228	212	9	stem	stem	NOUN
ct-9228	212	10	cells	cell	NOUN
ct-9228	212	11	.	.	PUNCT
ct-9228	213	1	cell	cell	NOUN
ct-9228	213	2	stem	stem	NOUN
ct-9228	213	3	cell	cell	NOUN
ct-9228	213	4	2018;22:25	2018;22:25	NUM
ct-9228	213	5	-	-	SYM
ct-9228	213	6	34	34	NUM
ct-9228	213	7	.	.	PUNCT
ct-9228	214	1	epub	epub	PROPN
ct-9228	214	2	2018/01/06	2018/01/06	NUM
ct-9228	214	3	.	.	PUNCT
ct-9228	215	1	doi	doi	NOUN
ct-9228	215	2	:	:	PUNCT
ct-9228	215	3	1	1	NUM
ct-9228	215	4	0.1016	0.1016	NUM
ct-9228	215	5	/	/	SYM
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ct-9228	215	7	.	.	PUNCT
ct-9228	216	1	pubmed	pubmed	PROPN
ct-9228	216	2	pmid	pmid	PROPN
ct-9228	216	3	:	:	PUNCT
ct-9228	216	4	29304340	29304340	NUM
ct-9228	216	5	.	.	PUNCT
ct-9228	217	1	29	29	NUM
ct-9228	217	2	.	.	X
ct-9228	217	3	treutlein	treutlein	PROPN
ct-9228	217	4	b	b	PROPN
ct-9228	217	5	,	,	PUNCT
ct-9228	217	6	lee	lee	PROPN
ct-9228	217	7	qy	qy	PROPN
ct-9228	217	8	,	,	PUNCT
ct-9228	217	9	camp	camp	NOUN
ct-9228	217	10	jg	jg	PROPN
ct-9228	217	11	,	,	PUNCT
ct-9228	217	12	et	et	PROPN
ct-9228	217	13	al	al	PROPN
ct-9228	217	14	:	:	PUNCT
ct-9228	217	15	dissecting	dissect	VERB
ct-9228	217	16	direct	direct	ADJ
ct-9228	217	17	reprogramming	reprogramming	NOUN
ct-9228	217	18	from	from	ADP
ct-9228	217	19	fibroblast	fibroblast	ADJ
ct-9228	217	20	to	to	ADP
ct-9228	217	21	neuron	neuron	NOUN
ct-9228	217	22	using	use	VERB
ct-9228	217	23	single	single	ADJ
ct-9228	217	24	-	-	PUNCT
ct-9228	217	25	cell	cell	NOUN
ct-9228	217	26	rna	rna	NOUN
ct-9228	217	27	-	-	PUNCT
ct-9228	217	28	seq	seq	NOUN
ct-9228	217	29	.	.	PUNCT
ct-9228	218	1	nature	nature	NOUN
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ct-9228	218	3	-	-	SYM
ct-9228	218	4	395	395	NUM
ct-9228	218	5	.	.	PUNCT
ct-9228	219	1	epub	epub	NOUN
ct-9228	219	2	2016/06/10	2016/06/10	NUM
ct-9228	219	3	.	.	PUNCT
ct-9228	220	1	doi	doi	NOUN
ct-9228	220	2	:	:	PUNCT
ct-9228	220	3	10.1038	10.1038	NUM
ct-9228	220	4	/	/	SYM
ct-9228	220	5	nature18323	nature18323	PROPN
ct-9228	220	6	.	.	PUNCT
ct-9228	221	1	pubmed	pubmed	PROPN
ct-9228	221	2	pmid	pmid	PROPN
ct-9228	221	3	:	:	PUNCT
ct-9228	221	4	27281220	27281220	NUM
ct-9228	221	5	;	;	PUNCT
ct-9228	221	6	pubmed	pubmed	PROPN
ct-9228	221	7	central	central	ADJ
ct-9228	221	8	pmcid	pmcid	NOUN
ct-9228	221	9	:	:	PUNCT
ct-9228	221	10	pmcpmc4928860	pmcpmc4928860	PROPN
ct-9228	221	11	.	.	PUNCT
ct-9228	222	1	30	30	NUM
ct-9228	222	2	.	.	PUNCT
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ct-9228	223	2	dl	dl	PROPN
ct-9228	223	3	:	:	PUNCT
ct-9228	223	4	directed	direct	VERB
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ct-9228	223	6	of	of	ADP
ct-9228	223	7	pluripotent	pluripotent	ADJ
ct-9228	223	8	stem	stem	NOUN
ct-9228	223	9	cells	cell	NOUN
ct-9228	223	10	in	in	ADP
ct-9228	223	11	vitro	vitro	VERB
ct-9228	223	12	.	.	PUNCT
ct-9228	224	1	in	in	ADP
ct-9228	224	2	:	:	PUNCT
ct-9228	224	3	gardiner	gardiner	PROPN
ct-9228	224	4	d	d	PROPN
ct-9228	224	5	,	,	PUNCT
ct-9228	224	6	editor	editor	NOUN
ct-9228	224	7	.	.	PUNCT
ct-9228	224	8	regenerative	regenerative	ADJ
ct-9228	224	9	engineering	engineering	NOUN
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ct-9228	224	11	developmental	developmental	ADJ
ct-9228	224	12	biology	biology	NOUN
ct-9228	224	13	.	.	PUNCT
ct-9228	225	1	boca	boca	PROPN
ct-9228	225	2	raton	raton	PROPN
ct-9228	225	3	,	,	PUNCT
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ct-9228	225	5	:	:	PUNCT
ct-9228	225	6	crc	crc	NOUN
ct-9228	225	7	press	press	NOUN
ct-9228	225	8	;	;	PUNCT
ct-9228	225	9	2017	2017	NUM
ct-9228	225	10	.	.	PUNCT
ct-9228	226	1	clinical	clinical	ADJ
ct-9228	226	2	theriogenology	theriogenology	NOUN
ct-9228	226	3	•	•	NOUN
ct-9228	226	4	volume	volume	NOUN
ct-9228	226	5	12	12	NUM
ct-9228	226	6	number	number	NOUN
ct-9228	226	7	3	3	NUM
ct-9228	226	8	•	•	NOUN
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ct-9228	226	10	2020188	2020188	NUM
ct-9228	226	11	008_ms-8	008_ms-8	PROPN
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