id sid tid token lemma pos ct-9465 1 1 2019 2019 NUM ct-9465 1 2 canine canine NOUN ct-9465 1 3 placental placental ADJ ct-9465 1 4 microbiome microbiome NOUN ct-9465 1 5         SPACE ct-9465 1 6 canine canine VERB ct-9465 1 7 placental placental ADJ ct-9465 1 8 microbiome microbiome ADJ ct-9465 1 9 jenny jenny NOUN ct-9465 1 10 sones sone NOUN ct-9465 1 11 , , PUNCT ct-9465 1 12 babiche babiche PROPN ct-9465 1 13 heil heil PROPN ct-9465 1 14 louisiana louisiana PROPN ct-9465 1 15 state state PROPN ct-9465 1 16 university university PROPN ct-9465 1 17 school school NOUN ct-9465 1 18 of of ADP ct-9465 1 19 veterinary veterinary ADJ ct-9465 1 20 medicine medicine NOUN ct-9465 1 21 department department NOUN ct-9465 1 22 of of ADP ct-9465 1 23 veterinary veterinary ADJ ct-9465 1 24 clinical clinical ADJ ct-9465 1 25 sciences science NOUN ct-9465 1 26 , , PUNCT ct-9465 1 27 baton baton NOUN ct-9465 1 28 rouge rouge NOUN ct-9465 1 29 , , PUNCT ct-9465 1 30 la la DET ct-9465 1 31 abstract abstract ADJ ct-9465 1 32 placenta placenta NOUN ct-9465 1 33 is be AUX ct-9465 1 34 a a DET ct-9465 1 35 pregnancy pregnancy NOUN ct-9465 1 36 - - PUNCT ct-9465 1 37 specific specific ADJ ct-9465 1 38 organ organ NOUN ct-9465 1 39 responsible responsible ADJ ct-9465 1 40 for for ADP ct-9465 1 41 maintenance maintenance NOUN ct-9465 1 42 of of ADP ct-9465 1 43 gestation gestation NOUN ct-9465 1 44 and and CCONJ ct-9465 1 45 offspring offspring NOUN ct-9465 1 46 survival survival NOUN ct-9465 1 47 in in ADP ct-9465 1 48 utero utero PROPN ct-9465 1 49 . . PUNCT ct-9465 2 1 similar similar ADJ ct-9465 2 2 to to ADP ct-9465 2 3 other other ADJ ct-9465 2 4 immune immune NOUN ct-9465 2 5 - - PUNCT ct-9465 2 6 privileged privileged ADJ ct-9465 2 7 sites site NOUN ct-9465 2 8 , , PUNCT ct-9465 2 9 fetoplacental fetoplacental ADJ ct-9465 2 10 unit unit NOUN ct-9465 2 11 was be AUX ct-9465 2 12 considered consider VERB ct-9465 2 13 sterile sterile ADJ ct-9465 2 14 . . PUNCT ct-9465 3 1 however however ADV ct-9465 3 2 , , PUNCT ct-9465 3 3 there there PRON ct-9465 3 4 is be VERB ct-9465 3 5 now now ADV ct-9465 3 6 strong strong ADJ ct-9465 3 7 evidence evidence NOUN ct-9465 3 8 in in ADP ct-9465 3 9 humans human NOUN ct-9465 3 10 that that SCONJ ct-9465 3 11 placenta placenta VERB ct-9465 3 12 harbors harbor VERB ct-9465 3 13 a a DET ct-9465 3 14 unique unique ADJ ct-9465 3 15 microbiome microbiome NOUN ct-9465 3 16 . . PUNCT ct-9465 4 1 although although SCONJ ct-9465 4 2 this this DET ct-9465 4 3 work work NOUN ct-9465 4 4 is be AUX ct-9465 4 5 in in ADP ct-9465 4 6 its its PRON ct-9465 4 7 infancy infancy NOUN ct-9465 4 8 in in ADP ct-9465 4 9 veterinary veterinary ADJ ct-9465 4 10 medicine medicine NOUN ct-9465 4 11 , , PUNCT ct-9465 4 12 there there PRON ct-9465 4 13 are be VERB ct-9465 4 14 accumulating accumulate VERB ct-9465 4 15 metagenetic metagenetic ADJ ct-9465 4 16 data datum NOUN ct-9465 4 17 to to PART ct-9465 4 18 support support VERB ct-9465 4 19 the the DET ct-9465 4 20 role role NOUN ct-9465 4 21 of of ADP ct-9465 4 22 maternal maternal ADJ ct-9465 4 23 reproductive reproductive ADJ ct-9465 4 24 tract tract NOUN ct-9465 4 25 microbiome microbiome NOUN ct-9465 4 26 in in ADP ct-9465 4 27 pregnancy pregnancy NOUN ct-9465 4 28 success success NOUN ct-9465 4 29 and and CCONJ ct-9465 4 30 adverse adverse ADJ ct-9465 4 31 outcomes outcome NOUN ct-9465 4 32 via via ADP ct-9465 4 33 placenta placenta PROPN ct-9465 4 34 . . PUNCT ct-9465 5 1 this this DET ct-9465 5 2 paper paper NOUN ct-9465 5 3 will will AUX ct-9465 5 4 review review VERB ct-9465 5 5 and and CCONJ ct-9465 5 6 highlight highlight VERB ct-9465 5 7 the the DET ct-9465 5 8 emerging emerge VERB ct-9465 5 9 field field NOUN ct-9465 5 10 of of ADP ct-9465 5 11 metagenetics metagenetic NOUN ct-9465 5 12 in in ADP ct-9465 5 13 canine canine NOUN ct-9465 5 14 reproductive reproductive ADJ ct-9465 5 15 medicine medicine NOUN ct-9465 5 16 . . PUNCT ct-9465 6 1 it it PRON ct-9465 6 2 will will AUX ct-9465 6 3 summarize summarize VERB ct-9465 6 4 what what PRON ct-9465 6 5 is be AUX ct-9465 6 6 known know VERB ct-9465 6 7 in in ADP ct-9465 6 8 humans human NOUN ct-9465 6 9 , , PUNCT ct-9465 6 10 as as ADV ct-9465 6 11 well well ADV ct-9465 6 12 as as ADP ct-9465 6 13 veterinary veterinary ADJ ct-9465 6 14 species specie NOUN ct-9465 6 15 , , PUNCT ct-9465 6 16 with with ADP ct-9465 6 17 an an DET ct-9465 6 18 emphasis emphasis NOUN ct-9465 6 19 on on ADP ct-9465 6 20 future future ADJ ct-9465 6 21 metagenetic metagenetic ADJ ct-9465 6 22 characterization characterization NOUN ct-9465 6 23 of of ADP ct-9465 6 24 a a DET ct-9465 6 25 canine canine NOUN ct-9465 6 26 placental placental NOUN ct-9465 6 27 microbiome microbiome NOUN ct-9465 6 28 and and CCONJ ct-9465 6 29 its its PRON ct-9465 6 30 potential potential ADJ ct-9465 6 31 role role NOUN ct-9465 6 32 in in ADP ct-9465 6 33 pregnancy pregnancy NOUN ct-9465 6 34 outcomes outcome NOUN ct-9465 6 35 . . PUNCT ct-9465 7 1 keywords keyword NOUN ct-9465 7 2 : : PUNCT ct-9465 7 3 dog dog NOUN ct-9465 7 4 , , PUNCT ct-9465 7 5 placenta placenta ADJ ct-9465 7 6 , , PUNCT ct-9465 7 7 uterus uterus NOUN ct-9465 7 8 , , PUNCT ct-9465 7 9 vagina vagina ADJ ct-9465 7 10 , , PUNCT ct-9465 7 11 microbiome microbiome ADJ ct-9465 7 12 introduction introduction NOUN ct-9465 7 13 placentation placentation NOUN ct-9465 7 14 mammalian mammalian NOUN ct-9465 7 15 placenta placenta NOUN ct-9465 7 16 is be AUX ct-9465 7 17 a a DET ct-9465 7 18 unique unique ADJ ct-9465 7 19 and and CCONJ ct-9465 7 20 transient transient ADJ ct-9465 7 21 organ organ NOUN ct-9465 7 22 of of ADP ct-9465 7 23 pregnancy pregnancy NOUN ct-9465 7 24 composed compose VERB ct-9465 7 25 of of ADP ct-9465 7 26 fetal fetal ADJ ct-9465 7 27 membranes membrane NOUN ct-9465 7 28 in in ADP ct-9465 7 29 intimate intimate ADJ ct-9465 7 30 association association NOUN ct-9465 7 31 with with ADP ct-9465 7 32 the the DET ct-9465 7 33 mother mother NOUN ct-9465 7 34 ’s ’s PART ct-9465 7 35 uterus uterus NOUN ct-9465 7 36 . . PUNCT ct-9465 8 1 in in ADP ct-9465 8 2 dog dog NOUN ct-9465 8 3 , , PUNCT ct-9465 8 4 embryo embryo NOUN ct-9465 8 5 first first ADV ct-9465 8 6 enters enter VERB ct-9465 8 7 uterus uterus NOUN ct-9465 8 8 approximately approximately ADV ct-9465 8 9 11 11 NUM ct-9465 8 10 days day NOUN ct-9465 8 11 after after ADP ct-9465 8 12 luteinizing luteinize VERB ct-9465 8 13 hormone hormone NOUN ct-9465 8 14 ( ( PUNCT ct-9465 8 15 lh lh PROPN ct-9465 8 16 ) ) PUNCT ct-9465 8 17 surge.1 surge.1 VERB ct-9465 9 1 embryos embryo NOUN ct-9465 9 2 then then ADV ct-9465 9 3 traverse traverse VERB ct-9465 9 4 the the DET ct-9465 9 5 uterine uterine ADJ ct-9465 9 6 body body NOUN ct-9465 9 7 and and CCONJ ct-9465 9 8 horns horn NOUN ct-9465 9 9 for for ADP ct-9465 9 10 several several ADJ ct-9465 9 11 days day NOUN ct-9465 9 12 before before ADP ct-9465 9 13 attaching attach VERB ct-9465 9 14 to to ADP ct-9465 9 15 endometrium endometrium NOUN ct-9465 9 16 at at ADP ct-9465 9 17 approximately approximately ADV ct-9465 9 18 22 22 NUM ct-9465 9 19 days day NOUN ct-9465 9 20 after after SCONJ ct-9465 9 21 lh lh PROPN ct-9465 9 22 surge surge VERB ct-9465 9 23 and and CCONJ ct-9465 9 24 the the DET ct-9465 9 25 trophoblast trophoblast ADJ ct-9465 9 26 invasion invasion NOUN ct-9465 9 27 process process NOUN ct-9465 9 28 begins begin VERB ct-9465 9 29 to to PART ct-9465 9 30 establish establish VERB ct-9465 9 31 an an DET ct-9465 9 32 uteroplacental uteroplacental ADJ ct-9465 9 33 interface interface NOUN ct-9465 9 34 and and CCONJ ct-9465 9 35 subsequently subsequently ADV ct-9465 9 36 a a DET ct-9465 9 37 fetoplacental fetoplacental ADJ ct-9465 9 38 unit unit NOUN ct-9465 9 39 . . PUNCT ct-9465 10 1 resulting result VERB ct-9465 10 2 canine canine NOUN ct-9465 10 3 placenta placenta NOUN ct-9465 10 4 is be AUX ct-9465 10 5 grossly grossly ADV ct-9465 10 6 defined define VERB ct-9465 10 7 as as ADP ct-9465 10 8 having have VERB ct-9465 10 9 a a DET ct-9465 10 10 zonary zonary ADJ ct-9465 10 11 shape shape NOUN ct-9465 10 12 , , PUNCT ct-9465 10 13 due due ADP ct-9465 10 14 to to ADP ct-9465 10 15 an an DET ct-9465 10 16 interdigitating interdigitate VERB ct-9465 10 17 zone zone NOUN ct-9465 10 18 of of ADP ct-9465 10 19 contact contact NOUN ct-9465 10 20 between between ADP ct-9465 10 21 endometrium endometrium NOUN ct-9465 10 22 and and CCONJ ct-9465 10 23 chorionic chorionic ADJ ct-9465 10 24 sac.2 sac.2 NOUN ct-9465 10 25 microscopically microscopically NOUN ct-9465 10 26 , , PUNCT ct-9465 10 27 this this DET ct-9465 10 28 contact contact NOUN ct-9465 10 29 has have VERB ct-9465 10 30 a a DET ct-9465 10 31 degree degree NOUN ct-9465 10 32 of of ADP ct-9465 10 33 intimacy intimacy NOUN ct-9465 10 34 that that PRON ct-9465 10 35 places place VERB ct-9465 10 36 trophoblast trophoblast ADJ ct-9465 10 37 cells cell NOUN ct-9465 10 38 in in ADP ct-9465 10 39 direct direct ADJ ct-9465 10 40 proximity proximity NOUN ct-9465 10 41 to to ADP ct-9465 10 42 the the DET ct-9465 10 43 interstitium interstitium NOUN ct-9465 10 44 of of ADP ct-9465 10 45 endometrium endometrium NOUN ct-9465 10 46 , , PUNCT ct-9465 10 47 but but CCONJ ct-9465 10 48 not not PART ct-9465 10 49 endometrial endometrial ADJ ct-9465 10 50 blood blood NOUN ct-9465 11 1 vessels.2 vessels.2 ADP ct-9465 11 2 therefore therefore ADV ct-9465 11 3 dogs dog NOUN ct-9465 11 4 have have VERB ct-9465 11 5 an an DET ct-9465 11 6 endotheliochorial endotheliochorial ADJ ct-9465 11 7 type type NOUN ct-9465 11 8 of of ADP ct-9465 11 9 placentation placentation NOUN ct-9465 11 10 , , PUNCT ct-9465 11 11 which which PRON ct-9465 11 12 is be AUX ct-9465 11 13 different different ADJ ct-9465 11 14 to to ADP ct-9465 11 15 hemochorial hemochorial ADJ ct-9465 11 16 type type NOUN ct-9465 11 17 in in ADP ct-9465 11 18 humans human NOUN ct-9465 11 19 that that PRON ct-9465 11 20 have have VERB ct-9465 11 21 trophoblast trophoblast ADJ ct-9465 11 22 cells cell NOUN ct-9465 11 23 exposed expose VERB ct-9465 11 24 to to ADP ct-9465 11 25 maternal maternal ADJ ct-9465 11 26 blood blood NOUN ct-9465 11 27 . . PUNCT ct-9465 12 1 horse horse NOUN ct-9465 12 2 placenta placenta PROPN ct-9465 12 3 is be AUX ct-9465 12 4 diffusely diffusely ADV ct-9465 12 5 villous villous ADJ ct-9465 12 6 and and CCONJ ct-9465 12 7 an an DET ct-9465 12 8 epitheliochorial epitheliochorial NOUN ct-9465 12 9 type,2 type,2 NUM ct-9465 12 10 which which PRON ct-9465 12 11 has have VERB ct-9465 12 12 6 6 NUM ct-9465 12 13 cell cell NOUN ct-9465 12 14 layers layer NOUN ct-9465 12 15 between between ADP ct-9465 12 16 maternal maternal ADJ ct-9465 12 17 and and CCONJ ct-9465 12 18 fetal fetal ADJ ct-9465 12 19 blood blood NOUN ct-9465 12 20 , , PUNCT ct-9465 12 21 giving give VERB ct-9465 12 22 it it PRON ct-9465 12 23 even even ADV ct-9465 12 24 less less ADJ ct-9465 12 25 intimacy intimacy NOUN ct-9465 12 26 than than ADP ct-9465 12 27 dog dog NOUN ct-9465 12 28 . . PUNCT ct-9465 13 1 these these DET ct-9465 13 2 macroscopic macroscopic ADJ ct-9465 13 3 and and CCONJ ct-9465 13 4 microscopic microscopic ADJ ct-9465 13 5 differences difference NOUN ct-9465 13 6 in in ADP ct-9465 13 7 placentation placentation NOUN ct-9465 13 8 are be AUX ct-9465 13 9 important important ADJ ct-9465 13 10 to to PART ct-9465 13 11 keep keep VERB ct-9465 13 12 in in ADP ct-9465 13 13 mind mind NOUN ct-9465 13 14 when when SCONJ ct-9465 13 15 making make VERB ct-9465 13 16 translations translation NOUN ct-9465 13 17 between between ADP ct-9465 13 18 human human ADJ ct-9465 13 19 microbiome microbiome NOUN ct-9465 13 20 data datum NOUN ct-9465 13 21 and and CCONJ ct-9465 13 22 that that PRON ct-9465 13 23 of of ADP ct-9465 13 24 veterinary veterinary ADJ ct-9465 13 25 species specie NOUN ct-9465 13 26 , , PUNCT ct-9465 13 27 including include VERB ct-9465 13 28 dogs dog NOUN ct-9465 13 29 . . PUNCT ct-9465 14 1 metagenetics metagenetics PROPN ct-9465 14 2 , , PUNCT ct-9465 14 3 metagenomics metagenomic NOUN ct-9465 14 4 , , PUNCT ct-9465 14 5 and and CCONJ ct-9465 14 6 microbiome microbiome NOUN ct-9465 14 7 due due ADP ct-9465 14 8 to to ADP ct-9465 14 9 the the DET ct-9465 14 10 emergence emergence NOUN ct-9465 14 11 of of ADP ct-9465 14 12 this this DET ct-9465 14 13 exciting exciting ADJ ct-9465 14 14 and and CCONJ ct-9465 14 15 novel novel ADJ ct-9465 14 16 field field NOUN ct-9465 14 17 in in ADP ct-9465 14 18 veterinary veterinary ADJ ct-9465 14 19 medicine medicine NOUN ct-9465 14 20 , , PUNCT ct-9465 14 21 academicians academician NOUN ct-9465 14 22 and and CCONJ ct-9465 14 23 clinicians clinician NOUN ct-9465 14 24 alike alike ADV ct-9465 14 25 are be AUX ct-9465 14 26 rapidly rapidly ADV ct-9465 14 27 learning learn VERB ct-9465 14 28 microbiome microbiome ADJ ct-9465 14 29 terms term NOUN ct-9465 14 30 and and CCONJ ct-9465 14 31 concepts concept NOUN ct-9465 14 32 . . PUNCT ct-9465 15 1 entire entire ADJ ct-9465 15 2 microbiota microbiota NOUN ct-9465 15 3 community community NOUN ct-9465 15 4 is be AUX ct-9465 15 5 considered consider VERB ct-9465 15 6 when when SCONJ ct-9465 15 7 assessing assess VERB ct-9465 15 8 the the DET ct-9465 15 9 microbiome microbiome NOUN ct-9465 15 10 of of ADP ct-9465 15 11 any any DET ct-9465 15 12 given give VERB ct-9465 15 13 environment environment NOUN ct-9465 15 14 . . PUNCT ct-9465 16 1 microbiota microbiota NOUN ct-9465 16 2 consists consist VERB ct-9465 16 3 of of ADP ct-9465 16 4 resident resident ADJ ct-9465 16 5 bacteria bacteria NOUN ct-9465 16 6 , , PUNCT ct-9465 16 7 archaea archaea NOUN ct-9465 16 8 , , PUNCT ct-9465 16 9 fungi fungus NOUN ct-9465 16 10 , , PUNCT ct-9465 16 11 protists protist NOUN ct-9465 16 12 , , PUNCT ct-9465 16 13 and and CCONJ ct-9465 16 14 viruses virus NOUN ct-9465 16 15 in in ADP ct-9465 16 16 the the DET ct-9465 16 17 environment environment NOUN ct-9465 16 18 of of ADP ct-9465 16 19 interest interest NOUN ct-9465 16 20 . . PUNCT ct-9465 17 1 microbiome microbiome NOUN ct-9465 17 2 is be AUX ct-9465 17 3 therefore therefore ADV ct-9465 17 4 the the DET ct-9465 17 5 collective collective ADJ ct-9465 17 6 genomes genome NOUN ct-9465 17 7 of of ADP ct-9465 17 8 the the DET ct-9465 17 9 microbiota microbiota NOUN ct-9465 17 10 community community NOUN ct-9465 17 11 members member NOUN ct-9465 17 12 and and CCONJ ct-9465 17 13 the the DET ct-9465 17 14 study study NOUN ct-9465 17 15 of of ADP ct-9465 17 16 this this PRON ct-9465 17 17 has have AUX ct-9465 17 18 been be AUX ct-9465 17 19 termed term VERB ct-9465 17 20 metagenomics metagenomic NOUN ct-9465 17 21 . . PUNCT ct-9465 18 1 study study NOUN ct-9465 18 2 of of ADP ct-9465 18 3 an an DET ct-9465 18 4 environment environment NOUN ct-9465 18 5 ’s ’s PART ct-9465 18 6 metagenome metagenome ADJ ct-9465 18 7 , , PUNCT ct-9465 18 8 where where SCONJ ct-9465 18 9 scientists scientist NOUN ct-9465 18 10 utilize utilize VERB ct-9465 18 11 the the DET ct-9465 18 12 principles principle NOUN ct-9465 18 13 of of ADP ct-9465 18 14 molecular molecular ADJ ct-9465 18 15 biology biology NOUN ct-9465 18 16 and and CCONJ ct-9465 18 17 genetics genetic NOUN ct-9465 18 18 , , PUNCT ct-9465 18 19 is be AUX ct-9465 18 20 referred refer VERB ct-9465 18 21 to to ADP ct-9465 18 22 as as ADP ct-9465 18 23 metagenetics metagenetic NOUN ct-9465 18 24 . . PUNCT ct-9465 19 1 sequencing sequence VERB ct-9465 19 2 of of ADP ct-9465 19 3 metagenome metagenome ADJ ct-9465 19 4 results result NOUN ct-9465 19 5 in in ADP ct-9465 19 6 read read NOUN ct-9465 19 7 lengths length NOUN ct-9465 19 8 of of ADP ct-9465 19 9 significant significant ADJ ct-9465 19 10 depth depth NOUN ct-9465 19 11 that that SCONJ ct-9465 19 12 bacterial bacterial ADJ ct-9465 19 13 genus genus NOUN ct-9465 19 14 and and CCONJ ct-9465 19 15 species specie NOUN ct-9465 19 16 can can AUX ct-9465 19 17 be be AUX ct-9465 19 18 accurately accurately ADV ct-9465 19 19 identified identify VERB ct-9465 19 20 and and CCONJ ct-9465 19 21 organized organize VERB ct-9465 19 22 into into ADP ct-9465 19 23 operational operational ADJ ct-9465 19 24 taxonomic taxonomic ADJ ct-9465 19 25 units unit NOUN ct-9465 19 26 ( ( PUNCT ct-9465 19 27 otus otus NOUN ct-9465 19 28 ) ) PUNCT ct-9465 19 29 that that PRON ct-9465 19 30 are be AUX ct-9465 19 31 mapped map VERB ct-9465 19 32 to to PART ct-9465 19 33 previously previously ADV ct-9465 19 34 generated generate VERB ct-9465 19 35 bacterial bacterial ADJ ct-9465 19 36 taxonomic taxonomic ADJ ct-9465 19 37 databases database NOUN ct-9465 19 38 . . PUNCT ct-9465 20 1 herein herein NOUN ct-9465 20 2 , , PUNCT ct-9465 20 3 bacterial bacterial ADJ ct-9465 20 4 microbiota microbiota NOUN ct-9465 20 5 of of ADP ct-9465 20 6 the the DET ct-9465 20 7 female female ADJ ct-9465 20 8 reproductive reproductive ADJ ct-9465 20 9 tract tract NOUN ct-9465 20 10 ( ( PUNCT ct-9465 20 11 environment environment NOUN ct-9465 20 12 ) ) PUNCT ct-9465 20 13 will will AUX ct-9465 20 14 be be AUX ct-9465 20 15 considered consider VERB ct-9465 20 16 in in ADP ct-9465 20 17 the the DET ct-9465 20 18 context context NOUN ct-9465 20 19 of of ADP ct-9465 20 20 pregnancy pregnancy NOUN ct-9465 20 21 outcomes outcome NOUN ct-9465 20 22 where where SCONJ ct-9465 20 23 the the DET ct-9465 20 24 host host NOUN ct-9465 20 25 is be AUX ct-9465 20 26 the the DET ct-9465 20 27 fetus fetus NOUN ct-9465 20 28 and and CCONJ ct-9465 20 29 dam dam NOUN ct-9465 20 30 . . PROPN ct-9465 21 1 633 633 NUM ct-9465 21 2 clinical clinical ADJ ct-9465 21 3 theriogenology theriogenology NOUN ct-9465 21 4 • • NOUN ct-9465 21 5 volume volume NOUN ct-9465 21 6 11 11 NUM ct-9465 21 7 , , PUNCT ct-9465 21 8 number number NOUN ct-9465 21 9 4 4 NUM ct-9465 21 10 • • NOUN ct-9465 21 11 december december PROPN ct-9465 21 12 2019 2019 NUM ct-9465 21 13         SPACE ct-9465 21 14 female female ADJ ct-9465 21 15 reproductive reproductive ADJ ct-9465 21 16 tract tract NOUN ct-9465 21 17 microbiome microbiome ADJ ct-9465 21 18 role role NOUN ct-9465 21 19 of of ADP ct-9465 21 20 vaginal vaginal ADJ ct-9465 21 21 and and CCONJ ct-9465 21 22 uterine uterine ADJ ct-9465 21 23 microbiome microbiome NOUN ct-9465 21 24 interactions interaction NOUN ct-9465 21 25 between between ADP ct-9465 21 26 host host NOUN ct-9465 21 27 and and CCONJ ct-9465 21 28 bacteria bacteria NOUN ct-9465 21 29 it it PRON ct-9465 21 30 supports support VERB ct-9465 21 31 has have AUX ct-9465 21 32 long long ADV ct-9465 21 33 been be AUX ct-9465 21 34 recognized recognize VERB ct-9465 21 35 ; ; PUNCT ct-9465 21 36 however however ADV ct-9465 21 37 , , PUNCT ct-9465 21 38 many many ADJ ct-9465 21 39 questions question NOUN ct-9465 21 40 remain remain VERB ct-9465 21 41 regarding regard VERB ct-9465 21 42 how how SCONJ ct-9465 21 43 this this DET ct-9465 21 44 microbial microbial ADJ ct-9465 21 45 environment environment NOUN ct-9465 21 46 varies vary VERB ct-9465 21 47 within within ADP ct-9465 21 48 and and CCONJ ct-9465 21 49 among among ADP ct-9465 21 50 individuals individual NOUN ct-9465 21 51 in in ADP ct-9465 21 52 both both CCONJ ct-9465 21 53 healthy healthy ADJ ct-9465 21 54 and and CCONJ ct-9465 21 55 diseased diseased ADJ ct-9465 21 56 states.3 states.3 NOUN ct-9465 21 57 human human ADJ ct-9465 21 58 vagina vagina NOUN ct-9465 21 59 is be AUX ct-9465 21 60 colonized colonize VERB ct-9465 21 61 with with ADP ct-9465 21 62 commensal commensal ADJ ct-9465 21 63 bacteria bacteria NOUN ct-9465 21 64 , , PUNCT ct-9465 21 65 predominantly predominantly ADV ct-9465 21 66 lactobacilli lactobacilli PROPN ct-9465 21 67 . . PUNCT ct-9465 22 1 therefore therefore ADV ct-9465 22 2 , , PUNCT ct-9465 22 3 a a DET ct-9465 22 4 vaginal vaginal ADJ ct-9465 22 5 microbiota microbiota NOUN ct-9465 22 6 has have AUX ct-9465 22 7 been be AUX ct-9465 22 8 proposed propose VERB ct-9465 22 9 to to PART ct-9465 22 10 have have VERB ct-9465 22 11 a a DET ct-9465 22 12 role role NOUN ct-9465 22 13 in in ADP ct-9465 22 14 female female ADJ ct-9465 22 15 reproductive reproductive ADJ ct-9465 22 16 physiology physiology NOUN ct-9465 22 17 , , PUNCT ct-9465 22 18 pathogen pathogen NOUN ct-9465 22 19 defense defense NOUN ct-9465 22 20 , , PUNCT ct-9465 22 21 and and CCONJ ct-9465 22 22 function.4 function.4 PROPN ct-9465 22 23 acidic acidic ADJ ct-9465 22 24 environment environment NOUN ct-9465 22 25 created create VERB ct-9465 22 26 by by ADP ct-9465 22 27 these these DET ct-9465 22 28 lactobacillus lactobacillus NOUN ct-9465 22 29 spp spp NOUN ct-9465 22 30 . . PUNCT ct-9465 22 31 is be AUX ct-9465 22 32 thought think VERB ct-9465 22 33 to to PART ct-9465 22 34 provide provide VERB ct-9465 22 35 the the DET ct-9465 22 36 first first ADJ ct-9465 22 37 barrier barrier NOUN ct-9465 22 38 of of ADP ct-9465 22 39 defense defense NOUN ct-9465 22 40 protecting protect VERB ct-9465 22 41 upper upper ADJ ct-9465 22 42 reproductive reproductive ADJ ct-9465 22 43 tract tract NOUN ct-9465 22 44 from from ADP ct-9465 22 45 opportunistic opportunistic ADJ ct-9465 22 46 pathogens pathogen NOUN ct-9465 22 47 in in ADP ct-9465 22 48 women.3,4 women.3,4 DET ct-9465 22 49 a a DET ct-9465 22 50 meta meta ADJ ct-9465 22 51 - - PUNCT ct-9465 22 52 analysis analysis NOUN ct-9465 22 53 provided provide VERB ct-9465 22 54 compelling compelling ADJ ct-9465 22 55 data datum NOUN ct-9465 22 56 in in ADP ct-9465 22 57 women woman NOUN ct-9465 22 58 to to PART ct-9465 22 59 support support VERB ct-9465 22 60 a a DET ct-9465 22 61 uterine uterine ADJ ct-9465 22 62 microbiome microbiome NOUN ct-9465 22 63 that that PRON ct-9465 22 64 may may AUX ct-9465 22 65 function function VERB ct-9465 22 66 to to PART ct-9465 22 67 modulate modulate VERB ct-9465 22 68 the the DET ct-9465 22 69 local local ADJ ct-9465 22 70 immune immune ADJ ct-9465 22 71 system system NOUN ct-9465 22 72 in in ADP ct-9465 22 73 preparation preparation NOUN ct-9465 22 74 for for ADP ct-9465 22 75 embryo embryo NOUN ct-9465 22 76 implantation implantation NOUN ct-9465 22 77 and and CCONJ ct-9465 22 78 placenta placenta PROPN ct-9465 22 79 formation.5 formation.5 PROPN ct-9465 22 80 when when SCONJ ct-9465 22 81 comparing compare VERB ct-9465 22 82 endometrial endometrial ADJ ct-9465 22 83 microbiota microbiota NOUN ct-9465 22 84 with with ADP ct-9465 22 85 vaginal vaginal ADJ ct-9465 22 86 and and CCONJ ct-9465 22 87 cervical cervical ADJ ct-9465 22 88 microbiota microbiota NOUN ct-9465 22 89 in in ADP ct-9465 22 90 women woman NOUN ct-9465 22 91 , , PUNCT ct-9465 22 92 endometrial endometrial ADJ ct-9465 22 93 microbiota microbiota NOUN ct-9465 22 94 was be AUX ct-9465 22 95 in in ADP ct-9465 22 96 general general ADJ ct-9465 22 97 lower lower ADV ct-9465 22 98 in in ADP ct-9465 22 99 relative relative ADJ ct-9465 22 100 abundance abundance NOUN ct-9465 22 101 , , PUNCT ct-9465 22 102 but but CCONJ ct-9465 22 103 with with ADP ct-9465 22 104 an an DET ct-9465 22 105 overall overall ADJ ct-9465 22 106 higher high ADJ ct-9465 22 107 microbial microbial ADJ ct-9465 22 108 diversity diversity NOUN ct-9465 22 109 and and CCONJ ct-9465 22 110 richness.4,6 richness.4,6 PROPN ct-9465 22 111 recently recently ADV ct-9465 22 112 , , PUNCT ct-9465 22 113 canine canine NOUN ct-9465 22 114 vaginal vaginal NOUN ct-9465 22 115 and and CCONJ ct-9465 22 116 uterine uterine ADJ ct-9465 22 117 microbiome microbiome NOUN ct-9465 22 118 was be AUX ct-9465 22 119 published.7 published.7 NOUN ct-9465 22 120 metagenetic metagenetic ADJ ct-9465 22 121 characterization characterization NOUN ct-9465 22 122 of of ADP ct-9465 22 123 canine canine ADJ ct-9465 22 124 vagina vagina NOUN ct-9465 22 125 and and CCONJ ct-9465 22 126 uterus uterus NOUN ct-9465 22 127 was be AUX ct-9465 22 128 obtained obtain VERB ct-9465 22 129 from from ADP ct-9465 22 130 vaginal vaginal ADJ ct-9465 22 131 swabs swab NOUN ct-9465 22 132 and and CCONJ ct-9465 22 133 endometrial endometrial ADJ ct-9465 22 134 tissue tissue NOUN ct-9465 22 135 samples sample NOUN ct-9465 22 136 , , PUNCT ct-9465 22 137 respectively respectively ADV ct-9465 22 138 , , PUNCT ct-9465 22 139 at at ADP ct-9465 22 140 elective elective ADJ ct-9465 22 141 ovariohysterectomy ovariohysterectomy NOUN ct-9465 22 142 . . PUNCT ct-9465 23 1 interestingly interestingly ADV ct-9465 23 2 , , PUNCT ct-9465 23 3 top top ADJ ct-9465 23 4 5 5 NUM ct-9465 23 5 genera genera NOUN ct-9465 23 6 identified identify VERB ct-9465 23 7 in in ADP ct-9465 23 8 the the DET ct-9465 23 9 vagina vagina NOUN ct-9465 23 10 consisted consist VERB ct-9465 23 11 of of ADP ct-9465 23 12 hydrotalea hydrotalea NOUN ct-9465 23 13 , , PUNCT ct-9465 23 14 ralstonia ralstonia NOUN ct-9465 23 15 , , PUNCT ct-9465 23 16 mycoplasma mycoplasma NOUN ct-9465 23 17 , , PUNCT ct-9465 23 18 fusobacterium fusobacterium NOUN ct-9465 23 19 , , PUNCT ct-9465 23 20 and and CCONJ ct-9465 23 21 streptococcus streptococcus VERB ct-9465 23 22 while while SCONJ ct-9465 23 23 top top ADJ ct-9465 23 24 5 5 NUM ct-9465 23 25 genera genera NOUN ct-9465 23 26 identified identify VERB ct-9465 23 27 in in ADP ct-9465 23 28 the the DET ct-9465 23 29 endometrium endometrium NOUN ct-9465 23 30 included include VERB ct-9465 23 31 pseudomonas pseudomona NOUN ct-9465 23 32 , , PUNCT ct-9465 23 33 staphylococcus staphylococcus NOUN ct-9465 23 34 , , PUNCT ct-9465 23 35 corynebacterium corynebacterium NOUN ct-9465 23 36 , , PUNCT ct-9465 23 37 anaplasma anaplasma NOUN ct-9465 23 38 , , PUNCT ct-9465 23 39 and and CCONJ ct-9465 23 40 dermacoccus dermacoccus NOUN ct-9465 23 41 . . PUNCT ct-9465 24 1 vagina vagina ADJ ct-9465 24 2 of of ADP ct-9465 24 3 bitch bitch NOUN ct-9465 24 4 is be AUX ct-9465 24 5 higher high ADJ ct-9465 24 6 in in ADP ct-9465 24 7 richness richness NOUN ct-9465 24 8 in in ADP ct-9465 24 9 contrast contrast NOUN ct-9465 24 10 to to PART ct-9465 24 11 canine canine VERB ct-9465 24 12 endometrial endometrial ADJ ct-9465 24 13 tissue tissue NOUN ct-9465 24 14 being be AUX ct-9465 24 15 higher high ADJ ct-9465 24 16 in in ADP ct-9465 24 17 diversity diversity NOUN ct-9465 24 18 . . PUNCT ct-9465 25 1 vagina vagina ADJ ct-9465 25 2 of of ADP ct-9465 25 3 estrual estrual ADJ ct-9465 25 4 bitch bitch NOUN ct-9465 25 5 had have VERB ct-9465 25 6 a a DET ct-9465 25 7 distinct distinct ADJ ct-9465 25 8 microbiome microbiome NOUN ct-9465 25 9 , , PUNCT ct-9465 25 10 whereas whereas SCONJ ct-9465 25 11 all all DET ct-9465 25 12 other other ADJ ct-9465 25 13 samples sample NOUN ct-9465 25 14 did do AUX ct-9465 25 15 not not PART ct-9465 25 16 distinctly distinctly ADV ct-9465 25 17 form form VERB ct-9465 25 18 clusters cluster NOUN ct-9465 25 19 , , PUNCT ct-9465 25 20 regardless regardless ADV ct-9465 25 21 of of ADP ct-9465 25 22 stage stage NOUN ct-9465 25 23 of of ADP ct-9465 25 24 the the DET ct-9465 25 25 estrous estrous ADJ ct-9465 25 26 cycle cycle NOUN ct-9465 25 27 . . PUNCT ct-9465 26 1 a a DET ct-9465 26 2 study study NOUN ct-9465 26 3 using use VERB ct-9465 26 4 multiple multiple ADJ ct-9465 26 5 sampling sample VERB ct-9465 26 6 techniques technique NOUN ct-9465 26 7 revealed reveal VERB ct-9465 26 8 that that SCONJ ct-9465 26 9 equine equine NOUN ct-9465 26 10 endometrium endometrium NOUN ct-9465 26 11 during during ADP ct-9465 26 12 estrus estrus NOUN ct-9465 26 13 has have VERB ct-9465 26 14 a a DET ct-9465 26 15 proteobacteria proteobacteria NOUN ct-9465 26 16 driven drive VERB ct-9465 26 17 microbiome microbiome NOUN ct-9465 26 18 , , PUNCT ct-9465 26 19 with with ADP ct-9465 26 20 no no DET ct-9465 26 21 significant significant ADJ ct-9465 26 22 difference difference NOUN ct-9465 26 23 between between ADP ct-9465 26 24 vaginal vaginal ADJ ct-9465 26 25 and and CCONJ ct-9465 26 26 endometrial endometrial ADJ ct-9465 26 27 microbiomes.8 microbiomes.8 PROPN ct-9465 26 28 also also ADV ct-9465 26 29 , , PUNCT ct-9465 26 30 there there PRON ct-9465 26 31 were be VERB ct-9465 26 32 no no DET ct-9465 26 33 significant significant ADJ ct-9465 26 34 differences difference NOUN ct-9465 26 35 between between ADP ct-9465 26 36 sampling sample VERB ct-9465 26 37 techniques technique NOUN ct-9465 26 38 : : PUNCT ct-9465 26 39 endometrial endometrial ADJ ct-9465 26 40 double double ADJ ct-9465 26 41 - - PUNCT ct-9465 26 42 guarded guard VERB ct-9465 26 43 swab swab NOUN ct-9465 26 44 , , PUNCT ct-9465 26 45 low low ADJ ct-9465 26 46 volume volume NOUN ct-9465 26 47 lavage lavage NOUN ct-9465 26 48 , , PUNCT ct-9465 26 49 or or CCONJ ct-9465 26 50 endometrial endometrial ADJ ct-9465 26 51 biopsy.8 biopsy.8 PROPN ct-9465 26 52 in in ADP ct-9465 26 53 contrast contrast NOUN ct-9465 26 54 , , PUNCT ct-9465 26 55 in in ADP ct-9465 26 56 another another DET ct-9465 26 57 study study NOUN ct-9465 26 58 , , PUNCT ct-9465 26 59 proteobacteria proteobacteria NOUN ct-9465 26 60 , , PUNCT ct-9465 26 61 firmicutes firmicute NOUN ct-9465 26 62 , , PUNCT ct-9465 26 63 bacteroidetes bacteroidete NOUN ct-9465 26 64 , , PUNCT ct-9465 26 65 and and CCONJ ct-9465 26 66 actinobacteria actinobacteria NOUN ct-9465 26 67 in in ADP ct-9465 26 68 cycling cycling NOUN ct-9465 26 69 equine equine NOUN ct-9465 26 70 endometrium endometrium NOUN ct-9465 26 71 was be AUX ct-9465 26 72 in in ADP ct-9465 26 73 contrast contrast NOUN ct-9465 26 74 to to ADP ct-9465 26 75 vaginal vaginal ADJ ct-9465 26 76 microbiome.9 microbiome.9 NOUN ct-9465 26 77 however however ADV ct-9465 26 78 , , PUNCT ct-9465 26 79 equine equine ADJ ct-9465 26 80 endometrial endometrial ADJ ct-9465 26 81 microbiome microbiome NOUN ct-9465 26 82 does do AUX ct-9465 26 83 appear appear VERB ct-9465 26 84 to to PART ct-9465 26 85 be be AUX ct-9465 26 86 different different ADJ ct-9465 26 87 in in ADP ct-9465 26 88 noncycling noncycle VERB ct-9465 26 89 mares mare NOUN ct-9465 26 90 when when SCONJ ct-9465 26 91 compared compare VERB ct-9465 26 92 to to ADP ct-9465 26 93 cycling cycle VERB ct-9465 26 94 mares mare NOUN ct-9465 26 95 during during ADP ct-9465 26 96 the the DET ct-9465 26 97 physiologic physiologic ADJ ct-9465 26 98 breeding breeding NOUN ct-9465 26 99 season season NOUN ct-9465 26 100 ( ( PUNCT ct-9465 26 101 unpublished unpublished ADJ ct-9465 26 102 data datum NOUN ct-9465 26 103 ) ) PUNCT ct-9465 26 104 . . PUNCT ct-9465 27 1 when when SCONJ ct-9465 27 2 making make VERB ct-9465 27 3 conclusions conclusion NOUN ct-9465 27 4 regarding regard VERB ct-9465 27 5 female female ADJ ct-9465 27 6 reproductive reproductive ADJ ct-9465 27 7 tract tract NOUN ct-9465 27 8 microbiome microbiome NOUN ct-9465 27 9 it it PRON ct-9465 27 10 is be AUX ct-9465 27 11 important important ADJ ct-9465 27 12 to to PART ct-9465 27 13 consider consider VERB ct-9465 27 14 the the DET ct-9465 27 15 stage stage NOUN ct-9465 27 16 of of ADP ct-9465 27 17 estrous estrous ADJ ct-9465 27 18 cycle cycle NOUN ct-9465 27 19 , , PUNCT ct-9465 27 20 which which PRON ct-9465 27 21 has have VERB ct-9465 27 22 unique unique ADJ ct-9465 27 23 sex sex NOUN ct-9465 27 24 steroid steroid NOUN ct-9465 27 25 hormone hormone NOUN ct-9465 27 26 influences influence NOUN ct-9465 27 27 , , PUNCT ct-9465 27 28 or or CCONJ ct-9465 27 29 lack lack NOUN ct-9465 27 30 thereof thereof ADV ct-9465 27 31 , , PUNCT ct-9465 27 32 on on ADP ct-9465 27 33 the the DET ct-9465 27 34 immune immune ADJ ct-9465 27 35 milieu milieu NOUN ct-9465 27 36 and and CCONJ ct-9465 27 37 potentially potentially ADV ct-9465 27 38 resident resident ADJ ct-9465 27 39 microbiome microbiome NOUN ct-9465 27 40 . . PUNCT ct-9465 28 1 further furth ADJ ct-9465 28 2 studies study NOUN ct-9465 28 3 are be AUX ct-9465 28 4 necessary necessary ADJ ct-9465 28 5 to to PART ct-9465 28 6 determine determine VERB ct-9465 28 7 a a DET ct-9465 28 8 “ " PUNCT ct-9465 28 9 core core NOUN ct-9465 28 10 ” " PUNCT ct-9465 28 11 vaginal vaginal ADJ ct-9465 28 12 and and CCONJ ct-9465 28 13 uterine uterine ADJ ct-9465 28 14 microbiome microbiome NOUN ct-9465 28 15 that that PRON ct-9465 28 16 is be AUX ct-9465 28 17 advantageous advantageous ADJ ct-9465 28 18 for for ADP ct-9465 28 19 pregnancy pregnancy NOUN ct-9465 28 20 success success NOUN ct-9465 28 21 in in ADP ct-9465 28 22 all all DET ct-9465 28 23 species specie NOUN ct-9465 28 24 , , PUNCT ct-9465 28 25 including include VERB ct-9465 28 26 dogs dog NOUN ct-9465 28 27 . . PUNCT ct-9465 29 1 with with ADP ct-9465 29 2 identification identification NOUN ct-9465 29 3 of of ADP ct-9465 29 4 canine canine ADJ ct-9465 29 5 reproductive reproductive ADJ ct-9465 29 6 tract tract NOUN ct-9465 29 7 microbiome microbiome NOUN ct-9465 29 8 , , PUNCT ct-9465 29 9 small small ADJ ct-9465 29 10 shifts shift NOUN ct-9465 29 11 in in ADP ct-9465 29 12 microbiomes microbiomes PROPN ct-9465 29 13 can can AUX ct-9465 29 14 be be AUX ct-9465 29 15 identified identify VERB ct-9465 29 16 that that PRON ct-9465 29 17 may may AUX ct-9465 29 18 not not PART ct-9465 29 19 be be AUX ct-9465 29 20 clinically clinically ADV ct-9465 29 21 apparent apparent ADJ ct-9465 29 22 or or CCONJ ct-9465 29 23 previously previously ADV ct-9465 29 24 detectable detectable ADJ ct-9465 29 25 using use VERB ct-9465 29 26 conventional conventional ADJ ct-9465 29 27 culture culture NOUN ct-9465 29 28 techniques technique NOUN ct-9465 29 29 , , PUNCT ct-9465 29 30 but but CCONJ ct-9465 29 31 could could AUX ct-9465 29 32 be be AUX ct-9465 29 33 clinically clinically ADV ct-9465 29 34 important important ADJ ct-9465 29 35 . . PUNCT ct-9465 30 1 evidence evidence NOUN ct-9465 30 2 for for ADP ct-9465 30 3 a a DET ct-9465 30 4 canine canine NOUN ct-9465 30 5 placental placental ADJ ct-9465 30 6 microbiome microbiome NOUN ct-9465 30 7 in in ADP ct-9465 30 8 both both DET ct-9465 30 9 women woman NOUN ct-9465 30 10 and and CCONJ ct-9465 30 11 veterinary veterinary ADJ ct-9465 30 12 species specie NOUN ct-9465 30 13 , , PUNCT ct-9465 30 14 placenta placenta PROPN ct-9465 30 15 has have AUX ct-9465 30 16 been be AUX ct-9465 30 17 regarded regard VERB ct-9465 30 18 as as ADP ct-9465 30 19 a a DET ct-9465 30 20 sterile sterile ADJ ct-9465 30 21 organ organ NOUN ct-9465 30 22 during during ADP ct-9465 30 23 pregnancy pregnancy NOUN ct-9465 30 24 . . PUNCT ct-9465 31 1 placenta placenta PROPN ct-9465 31 2 is be AUX ct-9465 31 3 responsible responsible ADJ ct-9465 31 4 for for ADP ct-9465 31 5 maternal maternal ADJ ct-9465 31 6 - - PUNCT ct-9465 31 7 fetal fetal ADJ ct-9465 31 8 exchanges exchange NOUN ct-9465 31 9 of of ADP ct-9465 31 10 nutrients nutrient NOUN ct-9465 31 11 and and CCONJ ct-9465 31 12 waste waste NOUN ct-9465 31 13 products product NOUN ct-9465 31 14 , , PUNCT ct-9465 31 15 as as ADV ct-9465 31 16 well well ADV ct-9465 31 17 as as ADP ct-9465 31 18 tolerance tolerance NOUN ct-9465 31 19 of of ADP ct-9465 31 20 semi semi ADJ ct-9465 31 21 - - ADJ ct-9465 31 22 allogeneic allogeneic ADJ ct-9465 31 23 fetus fetus NOUN ct-9465 31 24 that that PRON ct-9465 31 25 is be AUX ct-9465 31 26 composed compose VERB ct-9465 31 27 of of ADP ct-9465 31 28 maternal maternal ADJ ct-9465 31 29 and and CCONJ ct-9465 31 30 paternal paternal ADJ ct-9465 31 31 antigens.2 antigens.2 PROPN ct-9465 31 32 successful successful ADJ ct-9465 31 33 placental placental NOUN ct-9465 31 34 development development NOUN ct-9465 31 35 and and CCONJ ct-9465 31 36 fetal fetal ADJ ct-9465 31 37 survival survival NOUN ct-9465 31 38 relies rely VERB ct-9465 31 39 on on ADP ct-9465 31 40 immunotolerance immunotolerance NOUN ct-9465 31 41 by by ADP ct-9465 31 42 maternal maternal ADJ ct-9465 31 43 uterine uterine ADJ ct-9465 31 44 environment environment NOUN ct-9465 31 45 , , PUNCT ct-9465 31 46 which which PRON ct-9465 31 47 we we PRON ct-9465 31 48 are be AUX ct-9465 31 49 learning learn VERB ct-9465 31 50 is be AUX ct-9465 31 51 more more ADV ct-9465 31 52 diverse diverse ADJ ct-9465 31 53 and and CCONJ ct-9465 31 54 richer rich ADJ ct-9465 31 55 than than SCONJ ct-9465 31 56 previously previously ADV ct-9465 31 57 thought think VERB ct-9465 31 58 . . PUNCT ct-9465 32 1 it it PRON ct-9465 32 2 was be AUX ct-9465 32 3 recently recently ADV ct-9465 32 4 ( ( PUNCT ct-9465 32 5 2014 2014 NUM ct-9465 32 6 ) ) PUNCT ct-9465 32 7 reported report VERB ct-9465 32 8 that that SCONJ ct-9465 32 9 , , PUNCT ct-9465 32 10 based base VERB ct-9465 32 11 on on ADP ct-9465 32 12 metagenetic metagenetic ADJ ct-9465 32 13 techniques technique NOUN ct-9465 32 14 , , PUNCT ct-9465 32 15 human human ADJ ct-9465 32 16 placenta placenta NOUN ct-9465 32 17 harbors harbor VERB ct-9465 32 18 a a DET ct-9465 32 19 unique unique ADJ ct-9465 32 20 microbiome.3 microbiome.3 NOUN ct-9465 32 21 since since SCONJ ct-9465 32 22 then then ADV ct-9465 32 23 , , PUNCT ct-9465 32 24 nearly nearly ADV ct-9465 32 25 100 100 NUM ct-9465 32 26 new new ADJ ct-9465 32 27 studies study NOUN ct-9465 32 28 have have AUX ct-9465 32 29 been be AUX ct-9465 32 30 published publish VERB ct-9465 32 31 on on ADP ct-9465 32 32 the the DET ct-9465 32 33 human human ADJ ct-9465 32 34 placental placental NOUN ct-9465 32 35 microbiome microbiome NOUN ct-9465 32 36 and and CCONJ ct-9465 32 37 metagenetic metagenetic ADJ ct-9465 32 38 data datum NOUN ct-9465 32 39 are be AUX ct-9465 32 40 being be AUX ct-9465 32 41 generated generate VERB ct-9465 32 42 in in ADP ct-9465 32 43 several several ADJ ct-9465 32 44 veterinary veterinary ADJ ct-9465 32 45 species specie NOUN ct-9465 32 46 , , PUNCT ct-9465 32 47 including include VERB ct-9465 32 48 cows cow NOUN ct-9465 32 49 , , PUNCT ct-9465 32 50 dogs dog NOUN ct-9465 32 51 , , PUNCT ct-9465 32 52 and and CCONJ ct-9465 32 53 horses horse NOUN ct-9465 32 54 , , PUNCT ct-9465 32 55 that that PRON ct-9465 32 56 support support VERB ct-9465 32 57 a a DET ct-9465 32 58 unique unique ADJ ct-9465 32 59 placental placental ADJ ct-9465 32 60 microbiome microbiome NOUN ct-9465 32 61 similar similar ADJ ct-9465 32 62 to to ADP ct-9465 32 63 that that PRON ct-9465 32 64 in in ADP ct-9465 32 65 women woman NOUN ct-9465 32 66 . . PUNCT ct-9465 33 1 taxonomic taxonomic ADJ ct-9465 33 2 profile profile NOUN ct-9465 33 3 of of ADP ct-9465 33 4 human human ADJ ct-9465 33 5 placental placental ADJ ct-9465 33 6 microbiome microbiome NOUN ct-9465 33 7 was be AUX ct-9465 33 8 discovered discover VERB ct-9465 33 9 to to PART ct-9465 33 10 be be AUX ct-9465 33 11 most most ADV ct-9465 33 12 similar similar ADJ ct-9465 33 13 to to ADP ct-9465 33 14 oral oral ADJ ct-9465 33 15 microbiome microbiome NOUN ct-9465 33 16 , , PUNCT ct-9465 33 17 followed follow VERB ct-9465 33 18 closely closely ADV ct-9465 33 19 by by ADP ct-9465 33 20 vaginal vaginal ADJ ct-9465 33 21 microbiome microbiome NOUN ct-9465 33 22 and and CCONJ ct-9465 33 23 further far ADV ct-9465 33 24 from from ADP ct-9465 33 25 fecal fecal ADJ ct-9465 33 26 microbiome microbiome NOUN ct-9465 33 27 . . PUNCT ct-9465 34 1 bacterial bacterial ADJ ct-9465 34 2 dna dna PROPN ct-9465 34 3 was be AUX ct-9465 34 4 detected detect VERB ct-9465 34 5 in in ADP ct-9465 34 6 only only ADV ct-9465 34 7 50 50 NUM ct-9465 34 8 % % NOUN ct-9465 34 9 of of ADP ct-9465 34 10 human human ADJ ct-9465 34 11 placental placental ADJ ct-9465 34 12 tissue tissue NOUN ct-9465 34 13 samples.10 samples.10 NOUN ct-9465 34 14 based base VERB ct-9465 34 15 on on ADP ct-9465 34 16 these these DET ct-9465 34 17 positive positive ADJ ct-9465 34 18 samples sample NOUN ct-9465 34 19 , , PUNCT ct-9465 34 20 healthy healthy ADJ ct-9465 34 21 human human ADJ ct-9465 34 22 placental placental NOUN ct-9465 34 23 microbiome microbiome NOUN ct-9465 34 24 has have VERB ct-9465 34 25 an an DET ct-9465 34 26 abundance abundance NOUN ct-9465 34 27 of of ADP ct-9465 34 28 firmicutes firmicute NOUN ct-9465 34 29 , , PUNCT ct-9465 34 30 tenericutes tenericute NOUN ct-9465 34 31 , , PUNCT ct-9465 34 32 proteobacteria proteobacteria NOUN ct-9465 34 33 , , PUNCT ct-9465 34 34 634clinical 634clinical PROPN ct-9465 34 35 theriogenology theriogenology NOUN ct-9465 34 36 • • NOUN ct-9465 34 37 volume volume NOUN ct-9465 34 38 11 11 NUM ct-9465 34 39 , , PUNCT ct-9465 34 40 number number NOUN ct-9465 34 41 4 4 NUM ct-9465 34 42 • • NOUN ct-9465 34 43 december december PROPN ct-9465 34 44 2019 2019 NUM ct-9465 34 45         SPACE ct-9465 34 46 bacteroidetes bacteroidete NOUN ct-9465 34 47 , , PUNCT ct-9465 34 48 and and CCONJ ct-9465 34 49 fusobacteria.11 fusobacteria.11 ADJ ct-9465 34 50 despite despite SCONJ ct-9465 34 51 profound profound ADJ ct-9465 34 52 differences difference NOUN ct-9465 34 53 in in ADP ct-9465 34 54 placentation placentation NOUN ct-9465 34 55 , , PUNCT ct-9465 34 56 this this DET ct-9465 34 57 finding finding NOUN ct-9465 34 58 was be AUX ct-9465 34 59 consistent consistent ADJ ct-9465 34 60 in in ADP ct-9465 34 61 horses.1 horses.1 PROPN ct-9465 34 62 metagenetic metagenetic ADJ ct-9465 34 63 analyses analysis NOUN ct-9465 34 64 of of ADP ct-9465 34 65 the the DET ct-9465 34 66 equine equine NOUN ct-9465 34 67 placenta placenta NOUN ct-9465 34 68 , , PUNCT ct-9465 34 69 as as SCONJ ct-9465 34 70 done do VERB ct-9465 34 71 in in ADP ct-9465 34 72 humans human NOUN ct-9465 34 73 , , PUNCT ct-9465 34 74 demonstrated demonstrate VERB ct-9465 34 75 3 3 NUM ct-9465 34 76 main main ADJ ct-9465 34 77 phyla phyla NOUN ct-9465 34 78 in in ADP ct-9465 34 79 the the DET ct-9465 34 80 gravid gravid NOUN ct-9465 34 81 horn horn NOUN ct-9465 34 82 ( ( PUNCT ct-9465 34 83 firmicutes firmicute NOUN ct-9465 34 84 , , PUNCT ct-9465 34 85 proteobacteria proteobacteria NOUN ct-9465 34 86 , , PUNCT ct-9465 34 87 bacteroidetes bacteroidete NOUN ct-9465 34 88 ) ) PUNCT ct-9465 34 89 and and CCONJ ct-9465 34 90 those those DET ct-9465 34 91 same same ADJ ct-9465 34 92 3 3 NUM ct-9465 34 93 phyla phyla NOUN ct-9465 34 94 plus plus CCONJ ct-9465 34 95 actinobacteria actinobacteria NOUN ct-9465 34 96 in in ADP ct-9465 34 97 the the DET ct-9465 34 98 nongravid nongravid PROPN ct-9465 34 99 horn.12 horn.12 PROPN ct-9465 34 100 most most ADV ct-9465 34 101 abundant abundant ADJ ct-9465 34 102 bacterial bacterial ADJ ct-9465 34 103 phyla phyla NOUN ct-9465 34 104 in in ADP ct-9465 34 105 gravid gravid NOUN ct-9465 34 106 and and CCONJ ct-9465 34 107 nongravid nongravid PROPN ct-9465 34 108 chorioallantois chorioallantois PROPN ct-9465 34 109 share share VERB ct-9465 34 110 significant significant ADJ ct-9465 34 111 overlap overlap NOUN ct-9465 34 112 , , PUNCT ct-9465 34 113 suggesting suggest VERB ct-9465 34 114 similar similar ADJ ct-9465 34 115 , , PUNCT ct-9465 34 116 but but CCONJ ct-9465 34 117 not not PART ct-9465 34 118 identical identical ADJ ct-9465 34 119 , , PUNCT ct-9465 34 120 environments environment NOUN ct-9465 34 121 within within ADP ct-9465 34 122 different different ADJ ct-9465 34 123 compartments compartment NOUN ct-9465 34 124 of of ADP ct-9465 34 125 the the DET ct-9465 34 126 chorioallantois chorioallantois NOUN ct-9465 34 127 . . PUNCT ct-9465 35 1 many many ADJ ct-9465 35 2 of of ADP ct-9465 35 3 the the DET ct-9465 35 4 same same ADJ ct-9465 35 5 bacterial bacterial ADJ ct-9465 35 6 populations population NOUN ct-9465 35 7 that that PRON ct-9465 35 8 characterized characterize VERB ct-9465 35 9 gravid gravid NOUN ct-9465 35 10 chorioallantois chorioallantois NOUN ct-9465 35 11 described describe VERB ct-9465 35 12 by by ADP ct-9465 35 13 the the DET ct-9465 35 14 cornell cornell PROPN ct-9465 35 15 university university PROPN ct-9465 35 16 group group NOUN ct-9465 35 17 were be AUX ct-9465 35 18 also also ADV ct-9465 35 19 identified identify VERB ct-9465 35 20 in in ADP ct-9465 35 21 allantoic allantoic NOUN ct-9465 35 22 fluid fluid NOUN ct-9465 35 23 of of ADP ct-9465 35 24 pregnant pregnant ADJ ct-9465 35 25 mares mare NOUN ct-9465 35 26 by by ADP ct-9465 35 27 investigators investigator NOUN ct-9465 35 28 at at ADP ct-9465 35 29 oklahoma oklahoma PROPN ct-9465 35 30 state state PROPN ct-9465 35 31 university.9 university.9 PROPN ct-9465 35 32 figure figure NOUN ct-9465 35 33 . . PUNCT ct-9465 36 1 potential potential ADJ ct-9465 36 2 extra extra ADJ ct-9465 36 3 - - ADJ ct-9465 36 4 placental placental ADJ ct-9465 36 5 bacterial bacterial ADJ ct-9465 36 6 sources source NOUN ct-9465 36 7 ( ( PUNCT ct-9465 36 8 oral oral ADJ ct-9465 36 9 , , PUNCT ct-9465 36 10 fecal fecal ADJ ct-9465 36 11 , , PUNCT ct-9465 36 12 vaginal vaginal ADJ ct-9465 36 13 microbiota microbiota NOUN ct-9465 36 14 ) ) PUNCT ct-9465 36 15 for for ADP ct-9465 36 16 canine canine ADJ ct-9465 36 17 placental placental ADJ ct-9465 36 18 microbiome microbiome NOUN ct-9465 36 19 ; ; PUNCT ct-9465 36 20 canine canine PROPN ct-9465 36 21 fetoplacental fetoplacental ADJ ct-9465 36 22 units unit NOUN ct-9465 36 23 ( ( PUNCT ct-9465 36 24 pink pink ADJ ct-9465 36 25 ) ) PUNCT ct-9465 36 26 . . PUNCT ct-9465 37 1 it it PRON ct-9465 37 2 has have AUX ct-9465 37 3 been be AUX ct-9465 37 4 well well ADV ct-9465 37 5 established establish VERB ct-9465 37 6 that that SCONJ ct-9465 37 7 there there PRON ct-9465 37 8 is be VERB ct-9465 37 9 an an DET ct-9465 37 10 association association NOUN ct-9465 37 11 between between ADP ct-9465 37 12 bacterial bacterial ADJ ct-9465 37 13 infection infection NOUN ct-9465 37 14 of of ADP ct-9465 37 15 reproductive reproductive ADJ ct-9465 37 16 tract tract NOUN ct-9465 37 17 and and CCONJ ct-9465 37 18 fertility.13 fertility.13 VERB ct-9465 37 19 intense intense ADJ ct-9465 37 20 research research NOUN ct-9465 37 21 efforts effort NOUN ct-9465 37 22 are be AUX ct-9465 37 23 focused focus VERB ct-9465 37 24 on on ADP ct-9465 37 25 investigating investigate VERB ct-9465 37 26 bacterial bacterial ADJ ct-9465 37 27 endometritis endometritis NOUN ct-9465 37 28 in in ADP ct-9465 37 29 mare mare NOUN ct-9465 37 30 to to PART ct-9465 37 31 improve improve VERB ct-9465 37 32 fertility fertility NOUN ct-9465 37 33 and and CCONJ ct-9465 37 34 pregnancy pregnancy NOUN ct-9465 37 35 rates.14 rates.14 PROPN ct-9465 37 36 in in ADP ct-9465 37 37 dogs dog NOUN ct-9465 37 38 , , PUNCT ct-9465 37 39 relationship relationship NOUN ct-9465 37 40 between between ADP ct-9465 37 41 endometritis endometritis NOUN ct-9465 37 42 and and CCONJ ct-9465 37 43 conception conception NOUN ct-9465 37 44 and/or and/or CCONJ ct-9465 37 45 pregnancy pregnancy NOUN ct-9465 37 46 failure failure NOUN ct-9465 37 47 remains remain VERB ct-9465 37 48 unclear.15 unclear.15 ADJ ct-9465 37 49 transcervical transcervical ADJ ct-9465 37 50 catheterization catheterization NOUN ct-9465 37 51 by by ADP ct-9465 37 52 vaginal vaginal ADJ ct-9465 37 53 endoscopy endoscopy NOUN ct-9465 37 54 can can AUX ct-9465 37 55 be be AUX ct-9465 37 56 performed perform VERB ct-9465 37 57 to to PART ct-9465 37 58 evaluate evaluate VERB ct-9465 37 59 both both DET ct-9465 37 60 cytology cytology NOUN ct-9465 37 61 and and CCONJ ct-9465 37 62 bacteriology bacteriology NOUN ct-9465 37 63 . . PUNCT ct-9465 38 1 in in ADP ct-9465 38 2 a a DET ct-9465 38 3 study study NOUN ct-9465 38 4 where where SCONJ ct-9465 38 5 infertile infertile ADJ ct-9465 38 6 bitches bitch NOUN ct-9465 38 7 were be AUX ct-9465 38 8 examined examine VERB ct-9465 38 9 using use VERB ct-9465 38 10 transcervical transcervical ADJ ct-9465 38 11 catheterization catheterization NOUN ct-9465 38 12 , , PUNCT ct-9465 38 13 70 70 NUM ct-9465 38 14 % % NOUN ct-9465 38 15 had have VERB ct-9465 38 16 heavy heavy ADJ ct-9465 38 17 bacterial bacterial ADJ ct-9465 38 18 growth growth NOUN ct-9465 38 19 when when SCONJ ct-9465 38 20 samples sample NOUN ct-9465 38 21 were be AUX ct-9465 38 22 cultured cultured ADJ ct-9465 38 23 in in ADP ct-9465 38 24 vitro vitro VERB ct-9465 38 25 . . PUNCT ct-9465 39 1 the the DET ct-9465 39 2 most most ADV ct-9465 39 3 common common ADJ ct-9465 39 4 bacteria bacteria NOUN ct-9465 39 5 include include VERB ct-9465 39 6 pasteurella pasteurella PROPN ct-9465 39 7 multocida multocida PROPN ct-9465 39 8 , , PUNCT ct-9465 39 9 group group NOUN ct-9465 39 10 g g PROPN ct-9465 39 11 streptococcus streptococcus NOUN ct-9465 39 12 , , PUNCT ct-9465 39 13 staphylococcus staphylococcus NOUN ct-9465 39 14 intermedius intermedius NOUN ct-9465 39 15 , , PUNCT ct-9465 39 16 escherichia escherichia NOUN ct-9465 39 17 coli coli NOUN ct-9465 39 18 and and CCONJ ct-9465 39 19 proteus proteus NOUN ct-9465 39 20 mirabilis.15 mirabilis.15 NOUN ct-9465 39 21 these these DET ct-9465 39 22 pathogens pathogen NOUN ct-9465 39 23 could could AUX ct-9465 39 24 all all ADV ct-9465 39 25 potentially potentially ADV ct-9465 39 26 contribute contribute VERB ct-9465 39 27 to to ADP ct-9465 39 28 a a DET ct-9465 39 29 subclinical subclinical ADJ ct-9465 39 30 endometritis endometritis NOUN ct-9465 39 31 and and CCONJ ct-9465 39 32 even even ADV ct-9465 39 33 pyometra pyometra ADJ ct-9465 39 34 that that PRON ct-9465 39 35 may may AUX ct-9465 39 36 alter alter VERB ct-9465 39 37 fertility fertility NOUN ct-9465 39 38 as as ADV ct-9465 39 39 well well ADV ct-9465 39 40 as as ADP ct-9465 39 41 adverse adverse ADJ ct-9465 39 42 pregnancy pregnancy NOUN ct-9465 39 43 outcomes outcome NOUN ct-9465 39 44 including include VERB ct-9465 39 45 abortion abortion NOUN ct-9465 39 46 , , PUNCT ct-9465 39 47 stillbirth stillbirth NOUN ct-9465 39 48 of of ADP ct-9465 39 49 preterm preterm NOUN ct-9465 39 50 puppies puppy NOUN ct-9465 39 51 , , PUNCT ct-9465 39 52 and and CCONJ ct-9465 39 53 neonatal neonatal ADJ ct-9465 39 54 loss loss NOUN ct-9465 39 55 . . PUNCT ct-9465 40 1 reason reason NOUN ct-9465 40 2 why why SCONJ ct-9465 40 3 some some DET ct-9465 40 4 bitches bitch NOUN ct-9465 40 5 become become VERB ct-9465 40 6 pregnant pregnant ADJ ct-9465 40 7 and and CCONJ ct-9465 40 8 others other NOUN ct-9465 40 9 do do AUX ct-9465 40 10 not not PART ct-9465 40 11 is be AUX ct-9465 40 12 hypothesized hypothesize VERB ct-9465 40 13 to to PART ct-9465 40 14 be be AUX ct-9465 40 15 due due ADJ ct-9465 40 16 to to ADP ct-9465 40 17 the the DET ct-9465 40 18 immune immune ADJ ct-9465 40 19 milieu milieu NOUN ct-9465 40 20 of of ADP ct-9465 40 21 uterus uterus NOUN ct-9465 40 22 , , PUNCT ct-9465 40 23 which which PRON ct-9465 40 24 may may AUX ct-9465 40 25 be be AUX ct-9465 40 26 influenced influence VERB ct-9465 40 27 by by ADP ct-9465 40 28 a a DET ct-9465 40 29 resident resident ADJ ct-9465 40 30 microbiome microbiome NOUN ct-9465 40 31 ( ( PUNCT ct-9465 40 32 figure figure NOUN ct-9465 40 33 ) ) PUNCT ct-9465 40 34 . . PUNCT ct-9465 41 1 importantly importantly ADV ct-9465 41 2 , , PUNCT ct-9465 41 3 associations association NOUN ct-9465 41 4 between between ADP ct-9465 41 5 placental placental NOUN ct-9465 41 6 microbiome microbiome ADJ ct-9465 41 7 communities community NOUN ct-9465 41 8 and and CCONJ ct-9465 41 9 adverse adverse ADJ ct-9465 41 10 pregnancy pregnancy NOUN ct-9465 41 11 outcomes outcome NOUN ct-9465 41 12 in in ADP ct-9465 41 13 women woman NOUN ct-9465 41 14 , , PUNCT ct-9465 41 15 including include VERB ct-9465 41 16 preterm preterm ADJ ct-9465 41 17 birth birth NOUN ct-9465 41 18 and and CCONJ ct-9465 41 19 preeclampsia preeclampsia NOUN ct-9465 41 20 , , PUNCT ct-9465 41 21 are be AUX ct-9465 41 22 rapidly rapidly ADV ct-9465 41 23 being be AUX ct-9465 41 24 confirmed.3,6 confirmed.3,6 ADV ct-9465 41 25 these these DET ct-9465 41 26 new new ADJ ct-9465 41 27 data datum NOUN ct-9465 41 28 can can AUX ct-9465 41 29 serve serve VERB ct-9465 41 30 to to PART ct-9465 41 31 prevent prevent VERB ct-9465 41 32 maternal maternal ADJ ct-9465 41 33 and and CCONJ ct-9465 41 34 fetal fetal ADJ ct-9465 41 35 morbidity morbidity NOUN ct-9465 41 36 and and CCONJ ct-9465 41 37 mortality mortality NOUN ct-9465 41 38 via via ADP ct-9465 41 39 a a DET ct-9465 41 40 novel novel ADJ ct-9465 41 41 mechanism mechanism NOUN ct-9465 41 42 , , PUNCT ct-9465 41 43 i.e. i.e. X ct-9465 41 44 restoring restore VERB ct-9465 41 45 a a DET ct-9465 41 46 “ " PUNCT ct-9465 41 47 healthy healthy ADJ ct-9465 41 48 ” " PUNCT ct-9465 41 49 microbiota microbiota NOUN ct-9465 41 50 prior prior ADV ct-9465 41 51 to to ADP ct-9465 41 52 pregnancy pregnancy NOUN ct-9465 41 53 . . PUNCT ct-9465 42 1 preterm preterm ADJ ct-9465 42 2 birth birth NOUN ct-9465 42 3 and and CCONJ ct-9465 42 4 neonatal neonatal ADJ ct-9465 42 5 death death NOUN ct-9465 42 6 has have AUX ct-9465 42 7 been be AUX ct-9465 42 8 associated associate VERB ct-9465 42 9 with with ADP ct-9465 42 10 intrauterine intrauterine ADJ ct-9465 42 11 infections infection NOUN ct-9465 42 12 ascending ascend VERB ct-9465 42 13 from from ADP ct-9465 42 14 the the DET ct-9465 42 15 lower low ADJ ct-9465 42 16 genital genital ADJ ct-9465 42 17 tract.7 tract.7 NOUN ct-9465 42 18 in in ADP ct-9465 42 19 dogs dog NOUN ct-9465 42 20 , , PUNCT ct-9465 42 21 reproductive reproductive ADJ ct-9465 42 22 tract tract NOUN ct-9465 42 23 consists consist VERB ct-9465 42 24 of of ADP ct-9465 42 25 a a DET ct-9465 42 26 rich rich ADJ ct-9465 42 27 and and CCONJ ct-9465 42 28 diverse diverse ADJ ct-9465 42 29 microbial microbial ADJ ct-9465 42 30 environment environment NOUN ct-9465 42 31 with with ADP ct-9465 42 32 > > X ct-9465 42 33 300 300 NUM ct-9465 42 34 otus otus NOUN ct-9465 42 35 of of ADP ct-9465 42 36 organisms organism NOUN ct-9465 42 37 identified.16 identified.16 ADJ ct-9465 42 38 similar similar ADJ ct-9465 42 39 to to ADP ct-9465 42 40 humans human NOUN ct-9465 42 41 , , PUNCT ct-9465 42 42 presence presence NOUN ct-9465 42 43 of of ADP ct-9465 42 44 certain certain ADJ ct-9465 42 45 microbiota microbiota NOUN ct-9465 42 46 are be AUX ct-9465 42 47 either either CCONJ ct-9465 42 48 positively positively ADV ct-9465 42 49 or or CCONJ ct-9465 42 50 negatively negatively ADV ct-9465 42 51 associated associate VERB ct-9465 42 52 with with ADP ct-9465 42 53 pregnancy pregnancy NOUN ct-9465 42 54 outcome outcome NOUN ct-9465 42 55 . . PUNCT ct-9465 43 1 presence presence NOUN ct-9465 43 2 of of ADP ct-9465 43 3 the the DET ct-9465 43 4 any any PRON ct-9465 43 5 of of ADP ct-9465 43 6 the the DET ct-9465 43 7 genera genera NOUN ct-9465 43 8 biberstinia biberstinia NOUN ct-9465 43 9 , , PUNCT ct-9465 43 10 staphylococcus staphylococcus NOUN ct-9465 43 11 , , PUNCT ct-9465 43 12 pasteurella pasteurella PROPN ct-9465 43 13 , , PUNCT ct-9465 43 14 corynebacterium corynebacterium NOUN ct-9465 43 15 , , PUNCT ct-9465 43 16 or or CCONJ ct-9465 43 17 methylobacterium methylobacterium NOUN ct-9465 43 18 in in ADP ct-9465 43 19 vagina vagina NOUN ct-9465 43 20 of of ADP ct-9465 43 21 bitch bitch NOUN ct-9465 43 22 significantly significantly ADV ct-9465 43 23 increases increase VERB ct-9465 43 24 the the DET ct-9465 43 25 chance chance NOUN ct-9465 43 26 of of ADP ct-9465 43 27 a a DET ct-9465 43 28 stillborn stillborn ADJ ct-9465 43 29 puppy puppy NOUN ct-9465 43 30 in in ADP ct-9465 43 31 a a DET ct-9465 43 32 litter.17 litter.17 NOUN ct-9465 43 33 thus thus ADV ct-9465 43 34 , , PUNCT ct-9465 43 35 this this DET ct-9465 43 36 emerging emerge VERB ct-9465 43 37 and and CCONJ ct-9465 43 38 exciting exciting ADJ ct-9465 43 39 new new ADJ ct-9465 43 40 field field NOUN ct-9465 43 41 supports support VERB ct-9465 43 42 a a DET ct-9465 43 43 role role NOUN ct-9465 43 44 for for ADP ct-9465 43 45 a a DET ct-9465 43 46 symbiotic symbiotic ADJ ct-9465 43 47 microbiome microbiome NOUN ct-9465 43 48 at at ADP ct-9465 43 49 maternal maternal ADJ ct-9465 43 50 - - PUNCT ct-9465 43 51 fetal fetal ADJ ct-9465 43 52 interface interface NOUN ct-9465 43 53 that that PRON ct-9465 43 54 contributes contribute VERB ct-9465 43 55 to to ADP ct-9465 43 56 pregnancy pregnancy NOUN ct-9465 43 57 maintenance maintenance NOUN ct-9465 43 58 and and CCONJ ct-9465 43 59 success success NOUN ct-9465 43 60 . . PUNCT ct-9465 44 1 novel novel ADJ ct-9465 44 2 metagenetic metagenetic ADJ ct-9465 44 3 analyses analysis NOUN ct-9465 44 4 of of ADP ct-9465 44 5 the the DET ct-9465 44 6 canine canine NOUN ct-9465 44 7 placenta placenta NOUN ct-9465 44 8 will will AUX ct-9465 44 9 be be AUX ct-9465 44 10 important important ADJ ct-9465 44 11 to to PART ct-9465 44 12 enhance enhance VERB ct-9465 44 13 our our PRON ct-9465 44 14 understanding understanding NOUN ct-9465 44 15 of of ADP ct-9465 44 16 placental placental ADJ ct-9465 44 17 function function NOUN ct-9465 44 18 during during ADP ct-9465 44 19 pregnancy pregnancy NOUN ct-9465 44 20 in in ADP ct-9465 44 21 the the DET ct-9465 44 22 bitch bitch NOUN ct-9465 44 23 . . PUNCT ct-9465 45 1 establishment establishment NOUN ct-9465 45 2 of of ADP ct-9465 45 3 a a DET ct-9465 45 4 “ " PUNCT ct-9465 45 5 healthy healthy ADJ ct-9465 45 6 ” " PUNCT ct-9465 45 7 635 635 NUM ct-9465 45 8 clinical clinical ADJ ct-9465 45 9 theriogenology theriogenology NOUN ct-9465 45 10 • • NOUN ct-9465 45 11 volume volume NOUN ct-9465 45 12 11 11 NUM ct-9465 45 13 , , PUNCT ct-9465 45 14 number number NOUN ct-9465 45 15 4 4 NUM ct-9465 45 16 • • NOUN ct-9465 45 17 december december PROPN ct-9465 45 18 2019 2019 NUM ct-9465 45 19         SPACE ct-9465 45 20 reproductive reproductive ADJ ct-9465 45 21 tract tract NOUN ct-9465 45 22 microbiome microbiome NOUN ct-9465 45 23 could could AUX ct-9465 45 24 improve improve VERB ct-9465 45 25 pregnancy pregnancy NOUN ct-9465 45 26 outcomes outcome NOUN ct-9465 45 27 in in ADP ct-9465 45 28 sub sub ADJ ct-9465 45 29 / / ADJ ct-9465 45 30 infertile infertile ADJ ct-9465 45 31 bitches bitch NOUN ct-9465 45 32 . . PUNCT ct-9465 46 1 furthermore furthermore ADV ct-9465 46 2 , , PUNCT ct-9465 46 3 analysis analysis NOUN ct-9465 46 4 of of ADP ct-9465 46 5 canine canine NOUN ct-9465 46 6 placental placental ADJ ct-9465 46 7 microbiome microbiome NOUN ct-9465 46 8 in in ADP ct-9465 46 9 relation relation NOUN ct-9465 46 10 to to ADP ct-9465 46 11 other other ADJ ct-9465 46 12 extra extra ADJ ct-9465 46 13 - - ADJ ct-9465 46 14 placental placental ADJ ct-9465 46 15 body body NOUN ct-9465 46 16 sites site NOUN ct-9465 46 17 in in ADP ct-9465 46 18 healthy healthy ADJ ct-9465 46 19 bitches bitch NOUN ct-9465 46 20 , , PUNCT ct-9465 46 21 similar similar ADJ ct-9465 46 22 to to ADP ct-9465 46 23 what what PRON ct-9465 46 24 has have AUX ct-9465 46 25 been be AUX ct-9465 46 26 investigated investigate VERB ct-9465 46 27 in in ADP ct-9465 46 28 women woman NOUN ct-9465 46 29 and and CCONJ ct-9465 46 30 mares mare NOUN ct-9465 46 31 , , PUNCT ct-9465 46 32 will will AUX ct-9465 46 33 provide provide VERB ct-9465 46 34 foundation foundation NOUN ct-9465 46 35 for for ADP ct-9465 46 36 a a DET ct-9465 46 37 better well ADJ ct-9465 46 38 understanding understanding NOUN ct-9465 46 39 of of ADP ct-9465 46 40 the the DET ct-9465 46 41 relationship relationship NOUN ct-9465 46 42 between between ADP ct-9465 46 43 canine canine NOUN ct-9465 46 44 placenta placenta NOUN ct-9465 46 45 and and CCONJ ct-9465 46 46 resident resident ADJ ct-9465 46 47 bacterial bacterial ADJ ct-9465 46 48 populations population NOUN ct-9465 46 49 during during ADP ct-9465 46 50 uncomplicated uncomplicated ADJ ct-9465 46 51 healthy healthy ADJ ct-9465 46 52 and and CCONJ ct-9465 46 53 complicated complicated ADJ ct-9465 46 54 pregnancies pregnancy NOUN ct-9465 46 55 . . PUNCT ct-9465 47 1 methods method NOUN ct-9465 47 2 to to PART ct-9465 47 3 characterize characterize VERB ct-9465 47 4 canine canine NOUN ct-9465 47 5 placental placental ADJ ct-9465 47 6 microbiome microbiome NOUN ct-9465 47 7 by by ADP ct-9465 47 8 metagenetics metagenetic NOUN ct-9465 47 9 to to PART ct-9465 47 10 properly properly ADV ct-9465 47 11 assess assess VERB ct-9465 47 12 the the DET ct-9465 47 13 canine canine NOUN ct-9465 47 14 placental placental ADJ ct-9465 47 15 microbiome microbiome NOUN ct-9465 47 16 , , PUNCT ct-9465 47 17 samples sample NOUN ct-9465 47 18 should should AUX ct-9465 47 19 be be AUX ct-9465 47 20 collected collect VERB ct-9465 47 21 sterilely sterilely ADV ct-9465 47 22 at at ADP ct-9465 47 23 the the DET ct-9465 47 24 time time NOUN ct-9465 47 25 of of ADP ct-9465 47 26 caesarian caesarian ADJ ct-9465 47 27 section section NOUN ct-9465 47 28 . . PUNCT ct-9465 48 1 collection collection NOUN ct-9465 48 2 of of ADP ct-9465 48 3 fetal fetal ADJ ct-9465 48 4 membranes membrane NOUN ct-9465 48 5 after after ADP ct-9465 48 6 a a DET ct-9465 48 7 vaginal vaginal ADJ ct-9465 48 8 whelping whelping NOUN ct-9465 48 9 will will AUX ct-9465 48 10 have have VERB ct-9465 48 11 contamination contamination NOUN ct-9465 48 12 from from ADP ct-9465 48 13 the the DET ct-9465 48 14 vagina vagina NOUN ct-9465 48 15 . . PUNCT ct-9465 49 1 canine canine NOUN ct-9465 49 2 endometrium endometrium NOUN ct-9465 49 3 and and CCONJ ct-9465 49 4 vagina vagina NOUN ct-9465 49 5 have have VERB ct-9465 49 6 distinctly distinctly ADV ct-9465 49 7 different different ADJ ct-9465 49 8 microbiomes microbiome NOUN ct-9465 49 9 , , PUNCT ct-9465 49 10 collecting collect VERB ct-9465 49 11 conceptuses conceptus NOUN ct-9465 49 12 that that SCONJ ct-9465 49 13 traverse traverse VERB ct-9465 49 14 vaginal vaginal ADJ ct-9465 49 15 vault vault NOUN ct-9465 49 16 will will AUX ct-9465 49 17 likely likely ADV ct-9465 49 18 result result VERB ct-9465 49 19 in in ADP ct-9465 49 20 both both DET ct-9465 49 21 microbiomes microbiome NOUN ct-9465 49 22 being be AUX ct-9465 49 23 represented represent VERB ct-9465 49 24 . . PUNCT ct-9465 50 1 genomic genomic ADJ ct-9465 50 2 dna dna PROPN ct-9465 50 3 can can AUX ct-9465 50 4 be be AUX ct-9465 50 5 extracted extract VERB ct-9465 50 6 from from ADP ct-9465 50 7 various various ADJ ct-9465 50 8 types type NOUN ct-9465 50 9 of of ADP ct-9465 50 10 samples sample NOUN ct-9465 50 11 , , PUNCT ct-9465 50 12 such such ADJ ct-9465 50 13 as as ADP ct-9465 50 14 swabs swab NOUN ct-9465 50 15 , , PUNCT ct-9465 50 16 fluid fluid NOUN ct-9465 50 17 or or CCONJ ct-9465 50 18 tissue tissue NOUN ct-9465 50 19 using use VERB ct-9465 50 20 commercial commercial ADJ ct-9465 50 21 dna dna NOUN ct-9465 50 22 isolation isolation NOUN ct-9465 50 23 kits kit NOUN ct-9465 50 24 . . PUNCT ct-9465 51 1 after after ADP ct-9465 51 2 dna dna NOUN ct-9465 51 3 extraction extraction NOUN ct-9465 51 4 and and CCONJ ct-9465 51 5 purification purification NOUN ct-9465 51 6 , , PUNCT ct-9465 51 7 sample sample NOUN ct-9465 51 8 can can AUX ct-9465 51 9 be be AUX ct-9465 51 10 analyzed analyze VERB ct-9465 51 11 using use VERB ct-9465 51 12 multiple multiple ADJ ct-9465 51 13 molecular molecular ADJ ct-9465 51 14 genetic genetic ADJ ct-9465 51 15 techniques technique NOUN ct-9465 51 16 . . PUNCT ct-9465 52 1 these these PRON ct-9465 52 2 involve involve VERB ct-9465 52 3 isolation isolation NOUN ct-9465 52 4 of of ADP ct-9465 52 5 16s 16 NOUN ct-9465 52 6 ribosomal ribosomal NOUN ct-9465 52 7 dna dna NOUN ct-9465 52 8 and and CCONJ ct-9465 52 9 sequencing sequencing NOUN ct-9465 52 10 of of ADP ct-9465 52 11 amplified amplify VERB ct-9465 52 12 bacterial bacterial ADJ ct-9465 52 13 dna dna NOUN ct-9465 52 14 . . PUNCT ct-9465 53 1 therefore therefore ADV ct-9465 53 2 , , PUNCT ct-9465 53 3 metagenetic metagenetic ADJ ct-9465 53 4 techniques technique NOUN ct-9465 53 5 yield yield VERB ct-9465 53 6 live live ADJ ct-9465 53 7 and and CCONJ ct-9465 53 8 dead dead ADJ ct-9465 53 9 bacteria bacteria NOUN ct-9465 53 10 populations population NOUN ct-9465 53 11 . . PUNCT ct-9465 54 1 although although SCONJ ct-9465 54 2 dead dead ADJ ct-9465 54 3 and and CCONJ ct-9465 54 4 fragmented fragmented ADJ ct-9465 54 5 dna dna NOUN ct-9465 54 6 is be AUX ct-9465 54 7 not not PART ct-9465 54 8 replicating replicate VERB ct-9465 54 9 within within ADP ct-9465 54 10 a a DET ct-9465 54 11 host host NOUN ct-9465 54 12 , , PUNCT ct-9465 54 13 they they PRON ct-9465 54 14 still still ADV ct-9465 54 15 represent represent VERB ct-9465 54 16 ligands ligand NOUN ct-9465 54 17 for for ADP ct-9465 54 18 host host NOUN ct-9465 54 19 cells cell NOUN ct-9465 54 20 to to PART ct-9465 54 21 recognize recognize VERB ct-9465 54 22 and and CCONJ ct-9465 54 23 act act VERB ct-9465 54 24 upon upon SCONJ ct-9465 54 25 . . PUNCT ct-9465 55 1 therefore therefore ADV ct-9465 55 2 , , PUNCT ct-9465 55 3 these these DET ct-9465 55 4 inactive inactive ADJ ct-9465 55 5 bacterial bacterial ADJ ct-9465 55 6 fragments fragment NOUN ct-9465 55 7 could could AUX ct-9465 55 8 potentially potentially ADV ct-9465 55 9 still still ADV ct-9465 55 10 contribute contribute VERB ct-9465 55 11 to to ADP ct-9465 55 12 a a DET ct-9465 55 13 physiologic physiologic ADJ ct-9465 55 14 interaction interaction NOUN ct-9465 55 15 with with ADP ct-9465 55 16 the the DET ct-9465 55 17 host.5 host.5 PROPN ct-9465 55 18 a a DET ct-9465 55 19 second second ADJ ct-9465 55 20 pitfall pitfall NOUN ct-9465 55 21 includes include VERB ct-9465 55 22 quantification quantification NOUN ct-9465 55 23 of of ADP ct-9465 55 24 an an DET ct-9465 55 25 organism organism NOUN ct-9465 55 26 present present NOUN ct-9465 55 27 , , PUNCT ct-9465 55 28 despite despite SCONJ ct-9465 55 29 available available ADJ ct-9465 55 30 read read NOUN ct-9465 55 31 counts.18 counts.18 PROPN ct-9465 55 32 it it PRON ct-9465 55 33 is be AUX ct-9465 55 34 important important ADJ ct-9465 55 35 to to PART ct-9465 55 36 know know VERB ct-9465 55 37 that that SCONJ ct-9465 55 38 while while SCONJ ct-9465 55 39 traditional traditional ADJ ct-9465 55 40 identification identification NOUN ct-9465 55 41 of of ADP ct-9465 55 42 bacteria bacteria NOUN ct-9465 55 43 utilizes utilize VERB ct-9465 55 44 cultivating cultivate VERB ct-9465 55 45 methods method NOUN ct-9465 55 46 ( ( PUNCT ct-9465 55 47 i.e. i.e. X ct-9465 55 48 aerobic aerobic ADJ ct-9465 55 49 and and CCONJ ct-9465 55 50 anaerobic anaerobic ADJ ct-9465 55 51 culture culture NOUN ct-9465 55 52 ) ) PUNCT ct-9465 55 53 , , PUNCT ct-9465 55 54 metagenetic metagenetic ADJ ct-9465 55 55 techniques technique NOUN ct-9465 55 56 utilize utilize VERB ct-9465 55 57 non non ADJ ct-9465 55 58 - - ADJ ct-9465 55 59 cultivating cultivating ADJ ct-9465 55 60 methods method NOUN ct-9465 55 61 . . PUNCT ct-9465 56 1 metagenetic metagenetic ADJ ct-9465 56 2 analysis analysis NOUN ct-9465 56 3 of of ADP ct-9465 56 4 placenta placenta NOUN ct-9465 56 5 in in ADP ct-9465 56 6 horses horse NOUN ct-9465 56 7 should should AUX ct-9465 56 8 therefore therefore ADV ct-9465 56 9 be be AUX ct-9465 56 10 superior superior ADJ ct-9465 56 11 to to ADP ct-9465 56 12 cultivating cultivate VERB ct-9465 56 13 methods method NOUN ct-9465 56 14 that that PRON ct-9465 56 15 may may AUX ct-9465 56 16 fail fail VERB ct-9465 56 17 to to PART ct-9465 56 18 identify identify VERB ct-9465 56 19 dormant dormant ADJ ct-9465 56 20 bacteria bacteria NOUN ct-9465 56 21 that that PRON ct-9465 56 22 may may AUX ct-9465 56 23 reside reside VERB ct-9465 56 24 at at ADP ct-9465 56 25 the the DET ct-9465 56 26 maternal maternal ADJ ct-9465 56 27 - - PUNCT ct-9465 56 28 fetal fetal ADJ ct-9465 56 29 interface interface NOUN ct-9465 56 30 in in ADP ct-9465 56 31 pregnant pregnant ADJ ct-9465 56 32 mares mare NOUN ct-9465 56 33 . . PUNCT ct-9465 57 1 however however ADV ct-9465 57 2 , , PUNCT ct-9465 57 3 until until SCONJ ct-9465 57 4 these these DET ct-9465 57 5 new new ADJ ct-9465 57 6 methodologies methodology NOUN ct-9465 57 7 are be AUX ct-9465 57 8 robustly robustly ADV ct-9465 57 9 tested test VERB ct-9465 57 10 and and CCONJ ct-9465 57 11 validated validate VERB ct-9465 57 12 , , PUNCT ct-9465 57 13 the the DET ct-9465 57 14 clinician clinician NOUN ct-9465 57 15 should should AUX ct-9465 57 16 perform perform VERB ct-9465 57 17 cultivating cultivate VERB ct-9465 57 18 until until SCONJ ct-9465 57 19 noncultivating noncultivate VERB ct-9465 57 20 methods method NOUN ct-9465 57 21 are be AUX ct-9465 57 22 routinely routinely ADV ct-9465 57 23 available available ADJ ct-9465 57 24 and and CCONJ ct-9465 57 25 used use VERB ct-9465 57 26 . . PUNCT ct-9465 58 1 an an DET ct-9465 58 2 outline outline NOUN ct-9465 58 3 of of ADP ct-9465 58 4 a a DET ct-9465 58 5 suggested suggest VERB ct-9465 58 6 method method NOUN ct-9465 58 7 to to PART ct-9465 58 8 prospectively prospectively ADV ct-9465 58 9 collect collect VERB ct-9465 58 10 , , PUNCT ct-9465 58 11 process process NOUN ct-9465 58 12 , , PUNCT ct-9465 58 13 and and CCONJ ct-9465 58 14 analyze analyze VERB ct-9465 58 15 canine canine NOUN ct-9465 58 16 placenta placenta NOUN ct-9465 58 17 and and CCONJ ct-9465 58 18 extra extra ADJ ct-9465 58 19 - - ADJ ct-9465 58 20 placental placental ADJ ct-9465 58 21 sites site NOUN ct-9465 58 22 by by ADP ct-9465 58 23 metagenetic metagenetic ADJ ct-9465 58 24 techniques technique NOUN ct-9465 58 25 is be AUX ct-9465 58 26 as as SCONJ ct-9465 58 27 follows follow VERB ct-9465 58 28 : : PUNCT ct-9465 58 29 sample sample NOUN ct-9465 58 30 collection collection NOUN ct-9465 58 31 to to PART ct-9465 58 32 characterize characterize VERB ct-9465 58 33 the the DET ct-9465 58 34 canine canine NOUN ct-9465 58 35 placental placental ADJ ct-9465 58 36 microbiome microbiome NOUN ct-9465 58 37 , , PUNCT ct-9465 58 38 vaginal vaginal ADJ ct-9465 58 39 swab swab NOUN ct-9465 58 40 samples sample NOUN ct-9465 58 41 as as ADV ct-9465 58 42 well well ADV ct-9465 58 43 as as ADP ct-9465 58 44 collection collection NOUN ct-9465 58 45 of of ADP ct-9465 58 46 transcervical transcervical ADJ ct-9465 58 47 catheters catheter NOUN ct-9465 58 48 for for ADP ct-9465 58 49 endometrial endometrial ADJ ct-9465 58 50 metagenetic metagenetic ADJ ct-9465 58 51 sequencing sequencing NOUN ct-9465 58 52 will will AUX ct-9465 58 53 be be AUX ct-9465 58 54 first first ADV ct-9465 58 55 collected collect VERB ct-9465 58 56 during during ADP ct-9465 58 57 routine routine ADJ ct-9465 58 58 breeding breeding NOUN ct-9465 58 59 management management NOUN ct-9465 58 60 . . PUNCT ct-9465 59 1 in in ADP ct-9465 59 2 addition addition NOUN ct-9465 59 3 , , PUNCT ct-9465 59 4 swabs swab NOUN ct-9465 59 5 of of ADP ct-9465 59 6 the the DET ct-9465 59 7 buccal buccal ADJ ct-9465 59 8 mucosa mucosa NOUN ct-9465 59 9 of of ADP ct-9465 59 10 the the DET ct-9465 59 11 oral oral ADJ ct-9465 59 12 cavity cavity NOUN ct-9465 59 13 and and CCONJ ct-9465 59 14 a a DET ct-9465 59 15 fresh fresh ADJ ct-9465 59 16 fecal fecal ADJ ct-9465 59 17 sample sample NOUN ct-9465 59 18 will will AUX ct-9465 59 19 be be AUX ct-9465 59 20 collected collect VERB ct-9465 59 21 and and CCONJ ct-9465 59 22 stored store VERB ct-9465 59 23 at at ADP ct-9465 59 24 -80 -80 NOUN ct-9465 59 25 ° ° NOUN ct-9465 59 26 c c NOUN ct-9465 59 27 . . PUNCT ct-9465 60 1 at at ADP ct-9465 60 2 the the DET ct-9465 60 3 time time NOUN ct-9465 60 4 of of ADP ct-9465 60 5 pregnancy pregnancy NOUN ct-9465 60 6 confirmation confirmation NOUN ct-9465 60 7 , , PUNCT ct-9465 60 8 repeat repeat NOUN ct-9465 60 9 swabs swab NOUN ct-9465 60 10 of of ADP ct-9465 60 11 the the DET ct-9465 60 12 vaginal vaginal ADJ ct-9465 60 13 vault vault NOUN ct-9465 60 14 and and CCONJ ct-9465 60 15 from from ADP ct-9465 60 16 the the DET ct-9465 60 17 buccal buccal ADJ ct-9465 60 18 mucosa mucosa NOUN ct-9465 60 19 of of ADP ct-9465 60 20 the the DET ct-9465 60 21 oral oral ADJ ct-9465 60 22 cavity cavity NOUN ct-9465 60 23 , , PUNCT ct-9465 60 24 and and CCONJ ct-9465 60 25 a a DET ct-9465 60 26 fresh fresh ADJ ct-9465 60 27 fecal fecal ADJ ct-9465 60 28 sample sample NOUN ct-9465 60 29 will will AUX ct-9465 60 30 be be AUX ct-9465 60 31 collected collect VERB ct-9465 60 32 and and CCONJ ct-9465 60 33 stored store VERB ct-9465 60 34 at at ADP ct-9465 60 35 -80 -80 NOUN ct-9465 60 36 ° ° NOUN ct-9465 60 37 c c NOUN ct-9465 60 38 . . PUNCT ct-9465 61 1 at at ADP ct-9465 61 2 the the DET ct-9465 61 3 time time NOUN ct-9465 61 4 caesarean caesarean PROPN ct-9465 61 5 section section NOUN ct-9465 61 6 delivery delivery NOUN ct-9465 61 7 , , PUNCT ct-9465 61 8 placenta placenta NOUN ct-9465 61 9 including include VERB ct-9465 61 10 marginal marginal ADJ ct-9465 61 11 hematomas hematoma NOUN ct-9465 61 12 and and CCONJ ct-9465 61 13 amnion amnion NOUN ct-9465 61 14 will will AUX ct-9465 61 15 be be AUX ct-9465 61 16 collected collect VERB ct-9465 61 17 , , PUNCT ct-9465 61 18 dissected dissect VERB ct-9465 61 19 and and CCONJ ct-9465 61 20 stored store VERB ct-9465 61 21 at at ADP ct-9465 61 22 -80 -80 NOUN ct-9465 61 23 ° ° NOUN ct-9465 61 24 c c NOUN ct-9465 61 25 . . PUNCT ct-9465 62 1 dna dna PROPN ct-9465 62 2 isolation isolation NOUN ct-9465 62 3 and and CCONJ ct-9465 62 4 amplification amplification NOUN ct-9465 62 5 of of ADP ct-9465 62 6 16s 16s PROPN ct-9465 62 7 rrna rrna PROPN ct-9465 62 8 frozen frozen ADJ ct-9465 62 9 samples sample NOUN ct-9465 62 10 can can AUX ct-9465 62 11 be be AUX ct-9465 62 12 thawed thaw VERB ct-9465 62 13 and and CCONJ ct-9465 62 14 individually individually ADV ct-9465 62 15 processed process VERB ct-9465 62 16 for for ADP ct-9465 62 17 genomic genomic ADJ ct-9465 62 18 dna dna PROPN ct-9465 62 19 extraction extraction NOUN ct-9465 62 20 . . PUNCT ct-9465 63 1 this this PRON ct-9465 63 2 will will AUX ct-9465 63 3 be be AUX ct-9465 63 4 performed perform VERB ct-9465 63 5 according accord VERB ct-9465 63 6 to to ADP ct-9465 63 7 standard standard ADJ ct-9465 63 8 protocols protocol NOUN ct-9465 63 9 . . PUNCT ct-9465 64 1 samples sample NOUN ct-9465 64 2 homogenized homogenize VERB ct-9465 64 3 , , PUNCT ct-9465 64 4 centrifuged centrifuge VERB ct-9465 64 5 and and CCONJ ct-9465 64 6 resuspended resuspend VERB ct-9465 64 7 in in ADP ct-9465 64 8 nuclease nuclease NOUN ct-9465 64 9 - - PUNCT ct-9465 64 10 free free ADJ ct-9465 64 11 water water NOUN ct-9465 64 12 . . PUNCT ct-9465 65 1 an an DET ct-9465 65 2 equal equal ADJ ct-9465 65 3 volume volume NOUN ct-9465 65 4 of of ADP ct-9465 65 5 lysozyme lysozyme NOUN ct-9465 65 6 added add VERB ct-9465 65 7 and and CCONJ ct-9465 65 8 incubated incubate VERB ct-9465 65 9 for for ADP ct-9465 65 10 12 12 NUM ct-9465 65 11 hours hour NOUN ct-9465 65 12 at at ADP ct-9465 65 13 56 56 NUM ct-9465 65 14 ° ° ADP ct-9465 65 15 c c NOUN ct-9465 65 16 to to PART ct-9465 65 17 maximize maximize VERB ct-9465 65 18 bacterial bacterial ADJ ct-9465 65 19 dna dna PROPN ct-9465 65 20 extraction extraction NOUN ct-9465 65 21 . . PUNCT ct-9465 66 1 isolation isolation NOUN ct-9465 66 2 of of ADP ct-9465 66 3 dna dna PROPN ct-9465 66 4 performed perform VERB ct-9465 66 5 using use VERB ct-9465 66 6 a a DET ct-9465 66 7 commercial commercial ADJ ct-9465 66 8 dna dna NOUN ct-9465 66 9 isolation isolation NOUN ct-9465 66 10 kit kit NOUN ct-9465 66 11 powersoil powersoil NOUN ct-9465 66 12 ® ® PROPN ct-9465 66 13 ( ( PUNCT ct-9465 66 14 mo mo PROPN ct-9465 66 15 - - PUNCT ct-9465 66 16 bio bio PROPN ct-9465 66 17 laboratories laboratories PROPN ct-9465 66 18 inc inc PROPN ct-9465 66 19 ) ) PUNCT ct-9465 66 20 according accord VERB ct-9465 66 21 to to ADP ct-9465 66 22 the the DET ct-9465 66 23 manufacturer manufacturer NOUN ct-9465 66 24 ’s ’s PART ct-9465 66 25 instructions instruction NOUN ct-9465 66 26 . . PUNCT ct-9465 67 1 dna dna PROPN ct-9465 67 2 concentration concentration NOUN ct-9465 67 3 determined determine VERB ct-9465 67 4 using use VERB ct-9465 67 5 the the DET ct-9465 67 6 qubit qubit NOUN ct-9465 67 7 ® ® NOUN ct-9465 67 8 2.0 2.0 NUM ct-9465 67 9 flurometer flurometer NOUN ct-9465 67 10 ( ( PUNCT ct-9465 67 11 life life NOUN ct-9465 67 12 technologies technology NOUN ct-9465 67 13 , , PUNCT ct-9465 67 14 grand grand ADJ ct-9465 67 15 island island NOUN ct-9465 67 16 , , PUNCT ct-9465 67 17 ny ny PROPN ct-9465 67 18 ) ) PUNCT ct-9465 67 19 and and CCONJ ct-9465 67 20 dna dna PROPN ct-9465 67 21 integrity integrity NOUN ct-9465 67 22 assessed assess VERB ct-9465 67 23 by by ADP ct-9465 67 24 electrophoresis electrophoresis NOUN ct-9465 67 25 . . PUNCT ct-9465 68 1 the the DET ct-9465 68 2 v3 v3 PROPN ct-9465 68 3 and and CCONJ ct-9465 68 4 v4 v4 PROPN ct-9465 68 5 domain domain NOUN ct-9465 68 6 of of ADP ct-9465 68 7 bacterial bacterial ADJ ct-9465 68 8 16s 16 NOUN ct-9465 68 9 rrna8 rrna8 NOUN ct-9465 68 10 amplified amplify VERB ct-9465 68 11 by by ADP ct-9465 68 12 pcr pcr PROPN ct-9465 68 13 . . PUNCT ct-9465 69 1 primer primer NOUN ct-9465 69 2 sequence sequence NOUN ct-9465 69 3 for for ADP ct-9465 69 4 16s 16 NOUN ct-9465 69 5 amplicon amplicon NOUN ct-9465 69 6 pcr pcr PROPN ct-9465 69 7 is be AUX ct-9465 69 8 the the DET ct-9465 69 9 341f 341f PROPN ct-9465 69 10 and and CCONJ ct-9465 69 11 785r 785r VERB ct-9465 69 12 primers primer NOUN ct-9465 69 13 as as ADP ct-9465 69 14 previously previously ADV ct-9465 69 15 described9 described9 NOUN ct-9465 69 16 and and CCONJ ct-9465 69 17 optimized optimize VERB ct-9465 69 18 for for ADP ct-9465 69 19 the the DET ct-9465 69 20 illumina illumina PROPN ct-9465 69 21 miseq miseq PROPN ct-9465 69 22 platform platform PROPN ct-9465 69 23 . . PUNCT ct-9465 70 1 earth earth NOUN ct-9465 70 2 microbiome microbiome PROPN ct-9465 70 3 project project NOUN ct-9465 70 4 ( ( PUNCT ct-9465 70 5 http://www.earthmicrobiome.org)10 http://www.earthmicrobiome.org)10 PROPN ct-9465 70 6 can can AUX ct-9465 70 7 be be AUX ct-9465 70 8 used use VERB ct-9465 70 9 to to PART ct-9465 70 10 select select VERB ct-9465 70 11 150 150 NUM ct-9465 70 12 different different ADJ ct-9465 70 13 12 12 NUM ct-9465 70 14 bp bp NOUN ct-9465 70 15 error error NOUN ct-9465 70 16 - - PUNCT ct-9465 70 17 correcting correct VERB ct-9465 70 18 golay golay NOUN ct-9465 70 19 barcodes barcode NOUN ct-9465 70 20 for for ADP ct-9465 70 21 16s 16 NOUN ct-9465 70 22 rrna rrna PROPN ct-9465 70 23 , , PUNCT ct-9465 70 24 as as SCONJ ct-9465 70 25 described.9 described.9 PROPN ct-9465 70 26 the the DET ct-9465 70 27 pcr pcr ADJ ct-9465 70 28 reaction reaction NOUN ct-9465 70 29 performed perform VERB ct-9465 70 30 in in ADP ct-9465 70 31 triplicate triplicate NOUN ct-9465 70 32 containing contain VERB ct-9465 70 33 : : PUNCT ct-9465 70 34 microbial microbial ADJ ct-9465 70 35 genomic genomic NOUN ct-9465 70 36 dna dna NOUN ct-9465 70 37 ( ( PUNCT ct-9465 70 38 25 25 NUM ct-9465 70 39 ng ng PROPN ct-9465 70 40 ) ) PUNCT ct-9465 70 41 , , PUNCT ct-9465 70 42 1x 1x PROPN ct-9465 70 43 gotaq gotaq PROPN ct-9465 70 44 green green ADJ ct-9465 70 45 master master NOUN ct-9465 70 46 mix mix NOUN ct-9465 70 47 ( ( PUNCT ct-9465 70 48 promega promega PROPN ct-9465 70 49 , , PUNCT ct-9465 70 50 madison madison PROPN ct-9465 70 51 , , PUNCT ct-9465 70 52 wi wi PROPN ct-9465 70 53 ) ) PUNCT ct-9465 70 54 , , PUNCT ct-9465 70 55 1 1 NUM ct-9465 70 56 mm mm NOUN ct-9465 70 57 magnesium magnesium NOUN ct-9465 70 58 chloride chloride NOUN ct-9465 70 59 , , PUNCT ct-9465 70 60 and and CCONJ ct-9465 70 61 10 10 NUM ct-9465 70 62 µm µm NOUN ct-9465 70 63 of of ADP ct-9465 70 64 each each DET ct-9465 70 65 primer primer NOUN ct-9465 70 66 . . PUNCT ct-9465 71 1 the the DET ct-9465 71 2 pcr pcr ADJ ct-9465 71 3 conditions condition NOUN ct-9465 71 4 for for ADP ct-9465 71 5 16s 16 NOUN ct-9465 71 6 rrna rrna PROPN ct-9465 71 7 consist consist VERB ct-9465 71 8 of of ADP ct-9465 71 9 an an DET ct-9465 71 10 initial initial ADJ ct-9465 71 11 denaturation denaturation NOUN ct-9465 71 12 step step NOUN ct-9465 71 13 of of ADP ct-9465 71 14 3 3 NUM ct-9465 71 15 minutes minute NOUN ct-9465 71 16 at at ADP ct-9465 71 17 94 94 NUM ct-9465 71 18 ° ° NOUN ct-9465 71 19 c c NOUN ct-9465 71 20 ; ; PUNCT ct-9465 71 21 followed follow VERB ct-9465 71 22 by by ADP ct-9465 71 23 35 35 NUM ct-9465 71 24 cycles cycle NOUN ct-9465 71 25 of of ADP ct-9465 71 26 94 94 NUM ct-9465 71 27 ° ° ADP ct-9465 71 28 c c NOUN ct-9465 71 29 for for ADP ct-9465 71 30 636clinical 636clinical PROPN ct-9465 71 31 theriogenology theriogenology NOUN ct-9465 71 32 • • NOUN ct-9465 71 33 volume volume NOUN ct-9465 71 34 11 11 NUM ct-9465 71 35 , , PUNCT ct-9465 71 36 number number NOUN ct-9465 71 37 4 4 NUM ct-9465 71 38 • • NOUN ct-9465 71 39 december december PROPN ct-9465 71 40 2019 2019 NUM ct-9465 71 41         SPACE ct-9465 71 42 45 45 NUM ct-9465 71 43 seconds second NOUN ct-9465 71 44 , , PUNCT ct-9465 71 45 50 50 NUM ct-9465 71 46 ° ° NOUN ct-9465 71 47 c c NOUN ct-9465 71 48 for for ADP ct-9465 71 49 1 1 NUM ct-9465 71 50 minute minute NOUN ct-9465 71 51 , , PUNCT ct-9465 71 52 and and CCONJ ct-9465 72 1 72 72 NUM ct-9465 72 2 ° ° NOUN ct-9465 72 3 c c NOUN ct-9465 72 4 for for ADP ct-9465 72 5 90 90 NUM ct-9465 72 6 seconds second NOUN ct-9465 72 7 ; ; PUNCT ct-9465 72 8 and and CCONJ ct-9465 72 9 a a DET ct-9465 72 10 final final ADJ ct-9465 72 11 elongation elongation NOUN ct-9465 72 12 step step NOUN ct-9465 72 13 of of ADP ct-9465 72 14 72 72 NUM ct-9465 72 15 ° ° ADP ct-9465 72 16 c c NOUN ct-9465 72 17 for for ADP ct-9465 72 18 10 10 NUM ct-9465 72 19 minutes minute NOUN ct-9465 72 20 . . PUNCT ct-9465 73 1 no no DET ct-9465 73 2 template template NOUN ct-9465 73 3 controls control NOUN ct-9465 73 4 and and CCONJ ct-9465 73 5 2 2 NUM ct-9465 73 6 positive positive ADJ ct-9465 73 7 controls control NOUN ct-9465 73 8 ( ( PUNCT ct-9465 73 9 mock mock ADJ ct-9465 73 10 microbial microbial ADJ ct-9465 73 11 communities community NOUN ct-9465 73 12 ) ) PUNCT ct-9465 73 13 should should AUX ct-9465 73 14 be be AUX ct-9465 73 15 added add VERB ct-9465 73 16 to to ADP ct-9465 73 17 each each DET ct-9465 73 18 pcr pcr ADJ ct-9465 73 19 plate plate NOUN ct-9465 73 20 . . PUNCT ct-9465 74 1 replicate replicate VERB ct-9465 74 2 amplicons amplicon NOUN ct-9465 74 3 pooled pool VERB ct-9465 74 4 and and CCONJ ct-9465 74 5 purified purify VERB ct-9465 74 6 with with ADP ct-9465 74 7 a a DET ct-9465 74 8 qiaquick qiaquick NOUN ct-9465 74 9 pcr pcr NOUN ct-9465 74 10 purification purification NOUN ct-9465 74 11 kit kit NOUN ct-9465 74 12 ( ( PUNCT ct-9465 74 13 qiagen qiagen PROPN ct-9465 74 14 , , PUNCT ct-9465 74 15 valencia valencia PROPN ct-9465 74 16 , , PUNCT ct-9465 74 17 ca ca NOUN ct-9465 74 18 ) ) PUNCT ct-9465 74 19 and and CCONJ ct-9465 74 20 visualized visualize VERB ct-9465 74 21 by by ADP ct-9465 74 22 electrophoresis electrophoresi NOUN ct-9465 74 23 . . PUNCT ct-9465 75 1 amplicons amplicon NOUN ct-9465 75 2 are be AUX ct-9465 75 3 quantified quantify VERB ct-9465 75 4 using use VERB ct-9465 75 5 qubit qubit NOUN ct-9465 75 6 ® ® NOUN ct-9465 75 7 2.0 2.0 NUM ct-9465 75 8 flurometer flurometer NOUN ct-9465 75 9 then then ADV ct-9465 75 10 the the DET ct-9465 75 11 amplicon amplicon NOUN ct-9465 75 12 aliquots aliquot NOUN ct-9465 75 13 are be AUX ct-9465 75 14 standardized standardize VERB ct-9465 75 15 to to ADP ct-9465 75 16 the the DET ct-9465 75 17 same same ADJ ct-9465 75 18 concentration concentration NOUN ct-9465 75 19 . . PUNCT ct-9465 76 1 miseq miseq ADJ ct-9465 76 2 sequencing sequence VERB ct-9465 76 3 final final ADJ ct-9465 76 4 equimolar equimolar NOUN ct-9465 76 5 libraries library NOUN ct-9465 76 6 will will AUX ct-9465 76 7 be be AUX ct-9465 76 8 sequenced sequence VERB ct-9465 76 9 using use VERB ct-9465 76 10 the the DET ct-9465 76 11 miseq miseq ADJ ct-9465 76 12 reagent reagent ADJ ct-9465 76 13 kit kit NOUN ct-9465 76 14 v3 v3 PROPN ct-9465 76 15 ( ( PUNCT ct-9465 76 16 600 600 NUM ct-9465 76 17 cycles cycle NOUN ct-9465 76 18 ) ) PUNCT ct-9465 76 19 on on ADP ct-9465 76 20 the the DET ct-9465 76 21 miseq miseq NOUN ct-9465 76 22 platform platform NOUN ct-9465 76 23 ( ( PUNCT ct-9465 76 24 illumina illumina PROPN ct-9465 76 25 inc inc PROPN ct-9465 76 26 . . PROPN ct-9465 76 27 , , PUNCT ct-9465 76 28 san san PROPN ct-9465 76 29 diego diego PROPN ct-9465 76 30 , , PUNCT ct-9465 76 31 ca ca NOUN ct-9465 76 32 ) ) PUNCT ct-9465 76 33 . . PUNCT ct-9465 77 1 sequence sequence NOUN ct-9465 77 2 reads read VERB ct-9465 77 3 analyzed analyze VERB ct-9465 77 4 using use VERB ct-9465 77 5 the the DET ct-9465 77 6 quantitative quantitative ADJ ct-9465 77 7 insights insight NOUN ct-9465 77 8 into into ADP ct-9465 77 9 microbial microbial ADJ ct-9465 77 10 ecology ecology NOUN ct-9465 77 11 ( ( PUNCT ct-9465 77 12 qiime qiime NOUN ct-9465 77 13 ) ) PUNCT ct-9465 77 14 program program NOUN ct-9465 77 15 and and CCONJ ct-9465 77 16 assigned assign VERB ct-9465 77 17 to to ADP ct-9465 77 18 otus otus PROPN ct-9465 77 19 . . PUNCT ct-9465 78 1 discriminant discriminant ADJ ct-9465 78 2 analysis analysis NOUN ct-9465 78 3 is be AUX ct-9465 78 4 used use VERB ct-9465 78 5 to to PART ct-9465 78 6 evaluate evaluate VERB ct-9465 78 7 the the DET ct-9465 78 8 correlation correlation NOUN ct-9465 78 9 between between ADP ct-9465 78 10 bacterial bacterial ADJ ct-9465 78 11 taxa taxa NOUN ct-9465 78 12 and and CCONJ ct-9465 78 13 the the DET ct-9465 78 14 prevalence prevalence NOUN ct-9465 78 15 of of ADP ct-9465 78 16 each each DET ct-9465 78 17 bacteria bacteria NOUN ct-9465 78 18 identified identify VERB ct-9465 78 19 in in ADP ct-9465 78 20 the the DET ct-9465 78 21 placental placental NOUN ct-9465 78 22 samples sample NOUN ct-9465 78 23 against against ADP ct-9465 78 24 the the DET ct-9465 78 25 potential potential ADJ ct-9465 78 26 source source NOUN ct-9465 78 27 of of ADP ct-9465 78 28 bacteria bacteria NOUN ct-9465 78 29 from from ADP ct-9465 78 30 extra extra ADJ ct-9465 78 31 - - ADJ ct-9465 78 32 placental placental ADJ ct-9465 78 33 body body NOUN ct-9465 78 34 sites site NOUN ct-9465 78 35 . . PUNCT ct-9465 79 1 different different ADJ ct-9465 79 2 prevalence prevalence NOUN ct-9465 79 3 of of ADP ct-9465 79 4 bacteria bacteria NOUN ct-9465 79 5 in in ADP ct-9465 79 6 each each DET ct-9465 79 7 sample sample NOUN ct-9465 79 8 will will AUX ct-9465 79 9 be be AUX ct-9465 79 10 used use VERB ct-9465 79 11 as as ADP ct-9465 79 12 a a DET ct-9465 79 13 covariate covariate NOUN ct-9465 79 14 in in ADP ct-9465 79 15 a a DET ct-9465 79 16 stepwise stepwise ADJ ct-9465 79 17 discriminant discriminant ADJ ct-9465 79 18 analysis analysis NOUN ct-9465 79 19 model model NOUN ct-9465 79 20 . . PUNCT ct-9465 80 1 variables variable NOUN ct-9465 80 2 removed remove VERB ct-9465 80 3 in in ADP ct-9465 80 4 a a DET ct-9465 80 5 stepwise stepwise ADJ ct-9465 80 6 manner manner NOUN ct-9465 80 7 until until SCONJ ct-9465 80 8 the the DET ct-9465 80 9 only only ADJ ct-9465 80 10 variable variable NOUN ct-9465 80 11 with with ADP ct-9465 80 12 a a DET ct-9465 80 13 p p X ct-9465 80 14 < < X ct-9465 80 15 0.005 0.005 NUM ct-9465 80 16 is be AUX ct-9465 80 17 retained retain VERB ct-9465 80 18 in in ADP ct-9465 80 19 the the DET ct-9465 80 20 final final ADJ ct-9465 80 21 model model NOUN ct-9465 80 22 . . PUNCT ct-9465 81 1 significance significance NOUN ct-9465 81 2 preterm preterm NOUN ct-9465 81 3 birth birth NOUN ct-9465 81 4 of of ADP ct-9465 81 5 stillborn stillborn ADJ ct-9465 81 6 puppies puppy NOUN ct-9465 81 7 is be AUX ct-9465 81 8 not not PART ct-9465 81 9 an an DET ct-9465 81 10 uncommon uncommon ADJ ct-9465 81 11 outcome outcome NOUN ct-9465 81 12 of of ADP ct-9465 81 13 pregnancy pregnancy NOUN ct-9465 81 14 in in ADP ct-9465 81 15 dogs dog NOUN ct-9465 81 16 . . PUNCT ct-9465 82 1 diagnosing diagnose VERB ct-9465 82 2 the the DET ct-9465 82 3 cause cause NOUN ct-9465 82 4 of of ADP ct-9465 82 5 canine canine NOUN ct-9465 82 6 abortion abortion NOUN ct-9465 82 7 is be AUX ct-9465 82 8 best well ADV ct-9465 82 9 done do VERB ct-9465 82 10 through through ADP ct-9465 82 11 necropsy necropsy NOUN ct-9465 82 12 of of ADP ct-9465 82 13 fetuses fetus NOUN ct-9465 82 14 and and CCONJ ct-9465 82 15 fetal fetal ADJ ct-9465 82 16 membranes membrane NOUN ct-9465 82 17 . . PUNCT ct-9465 83 1 placental placental ADJ ct-9465 83 2 infection infection NOUN ct-9465 83 3 during during ADP ct-9465 83 4 canine canine ADJ ct-9465 83 5 pregnancy pregnancy NOUN ct-9465 83 6 can can AUX ct-9465 83 7 be be AUX ct-9465 83 8 extremely extremely ADV ct-9465 83 9 difficult difficult ADJ ct-9465 83 10 to to PART ct-9465 83 11 diagnose diagnose VERB ct-9465 83 12 , , PUNCT ct-9465 83 13 as as SCONJ ct-9465 83 14 outward outward ADJ ct-9465 83 15 clinical clinical ADJ ct-9465 83 16 signs sign NOUN ct-9465 83 17 are be AUX ct-9465 83 18 often often ADV ct-9465 83 19 not not PART ct-9465 83 20 present present ADJ ct-9465 83 21 or or CCONJ ct-9465 83 22 subtle subtle ADJ ct-9465 83 23 , , PUNCT ct-9465 83 24 consisting consist VERB ct-9465 83 25 of of ADP ct-9465 83 26 restlessness restlessness NOUN ct-9465 83 27 , , PUNCT ct-9465 83 28 vulvar vulvar NOUN ct-9465 83 29 discharge discharge NOUN ct-9465 83 30 , , PUNCT ct-9465 83 31 and and CCONJ ct-9465 83 32 lethargy lethargy NOUN ct-9465 83 33 . . PUNCT ct-9465 84 1 understanding understand VERB ct-9465 84 2 relationship relationship NOUN ct-9465 84 3 between between ADP ct-9465 84 4 canine canine NOUN ct-9465 84 5 placenta placenta NOUN ct-9465 84 6 and and CCONJ ct-9465 84 7 resident resident ADJ ct-9465 84 8 bacterial bacterial ADJ ct-9465 84 9 populations population NOUN ct-9465 84 10 of of ADP ct-9465 84 11 uterus uterus NOUN ct-9465 84 12 and and CCONJ ct-9465 84 13 vagina vagina NOUN ct-9465 84 14 could could AUX ct-9465 84 15 provide provide VERB ct-9465 84 16 opportunity opportunity NOUN ct-9465 84 17 to to PART ct-9465 84 18 establish establish VERB ct-9465 84 19 symbiosis symbiosis NOUN ct-9465 84 20 prior prior ADV ct-9465 84 21 to to ADP ct-9465 84 22 pregnancy pregnancy NOUN ct-9465 84 23 in in ADP ct-9465 84 24 order order NOUN ct-9465 84 25 to to PART ct-9465 84 26 aid aid VERB ct-9465 84 27 in in ADP ct-9465 84 28 pregnancy pregnancy NOUN ct-9465 84 29 success success NOUN ct-9465 84 30 . . PUNCT ct-9465 85 1 furthermore furthermore ADV ct-9465 85 2 , , PUNCT ct-9465 85 3 diagnosing diagnose VERB ct-9465 85 4 dysbiosis dysbiosis NOUN ct-9465 85 5 in in ADP ct-9465 85 6 uterus uterus NOUN ct-9465 85 7 before before ADP ct-9465 85 8 pregnancy pregnancy NOUN ct-9465 85 9 or or CCONJ ct-9465 85 10 even even ADV ct-9465 85 11 extra extra ADJ ct-9465 85 12 - - ADJ ct-9465 85 13 placental placental ADJ ct-9465 85 14 sites site NOUN ct-9465 85 15 ( ( PUNCT ct-9465 85 16 oral oral ADJ ct-9465 85 17 , , PUNCT ct-9465 85 18 gastrointestinal gastrointestinal ADJ ct-9465 85 19 and/or and/or CCONJ ct-9465 85 20 vaginal vaginal NOUN ct-9465 85 21 ) ) PUNCT ct-9465 85 22 could could AUX ct-9465 85 23 provide provide VERB ct-9465 85 24 evidence evidence NOUN ct-9465 85 25 for for ADP ct-9465 85 26 predicting predict VERB ct-9465 85 27 associated associate VERB ct-9465 85 28 adverse adverse ADJ ct-9465 85 29 outcomes outcome NOUN ct-9465 85 30 , , PUNCT ct-9465 85 31 such such ADJ ct-9465 85 32 as as ADP ct-9465 85 33 abortion abortion NOUN ct-9465 85 34 , , PUNCT ct-9465 85 35 in in ADP ct-9465 85 36 breeding breeding NOUN ct-9465 85 37 bitches bitch NOUN ct-9465 85 38 . . PUNCT ct-9465 86 1 identification identification NOUN ct-9465 86 2 of of ADP ct-9465 86 3 bacterial bacterial ADJ ct-9465 86 4 targets target NOUN ct-9465 86 5 in in ADP ct-9465 86 6 extra extra ADJ ct-9465 86 7 - - ADJ ct-9465 86 8 placental placental ADJ ct-9465 86 9 body body NOUN ct-9465 86 10 sites site NOUN ct-9465 86 11 and and CCONJ ct-9465 86 12 appropriate appropriate ADJ ct-9465 86 13 pre pre ADJ ct-9465 86 14 / / ADJ ct-9465 86 15 probiotic probiotic ADJ ct-9465 86 16 therapies therapy NOUN ct-9465 86 17 to to PART ct-9465 86 18 improve improve VERB ct-9465 86 19 adverse adverse ADJ ct-9465 86 20 pregnancy pregnancy NOUN ct-9465 86 21 outcomes outcome NOUN ct-9465 86 22 would would AUX ct-9465 86 23 greatly greatly ADV ct-9465 86 24 enhance enhance VERB ct-9465 86 25 breeding breeding NOUN ct-9465 86 26 management management NOUN ct-9465 86 27 and and CCONJ ct-9465 86 28 perinatal perinatal ADJ ct-9465 86 29 care care NOUN ct-9465 86 30 in in ADP ct-9465 86 31 our our PRON ct-9465 86 32 canine canine NOUN ct-9465 86 33 patients patient NOUN ct-9465 86 34 . . PUNCT ct-9465 87 1 authors author NOUN ct-9465 87 2 advise advise VERB ct-9465 87 3 caution caution NOUN ct-9465 87 4 and and CCONJ ct-9465 87 5 judicious judicious ADJ ct-9465 87 6 usage usage NOUN ct-9465 87 7 of of ADP ct-9465 87 8 interventions intervention NOUN ct-9465 87 9 to to PART ct-9465 87 10 alter alter VERB ct-9465 87 11 the the DET ct-9465 87 12 microbiome microbiome NOUN ct-9465 87 13 of of ADP ct-9465 87 14 canine canine ADJ ct-9465 87 15 reproductive reproductive ADJ ct-9465 87 16 tract tract NOUN ct-9465 87 17 to to PART ct-9465 87 18 improve improve VERB ct-9465 87 19 fertility fertility NOUN ct-9465 87 20 and and CCONJ ct-9465 87 21 pregnancy pregnancy NOUN ct-9465 87 22 outcomes outcome NOUN ct-9465 87 23 until until SCONJ ct-9465 87 24 an an DET ct-9465 87 25 exhaustive exhaustive ADJ ct-9465 87 26 microbiota microbiota NOUN ct-9465 87 27 characterization characterization NOUN ct-9465 87 28 has have AUX ct-9465 87 29 been be AUX ct-9465 87 30 performed perform VERB ct-9465 87 31 . . PUNCT ct-9465 88 1 conflict conflict NOUN ct-9465 88 2 of of ADP ct-9465 88 3 interest interest NOUN ct-9465 88 4 no no DET ct-9465 88 5 conflict conflict NOUN ct-9465 88 6 of of ADP ct-9465 88 7 interest interest NOUN ct-9465 88 8 to to PART ct-9465 88 9 declare declare VERB ct-9465 88 10 . . PUNCT ct-9465 89 1 references reference NOUN ct-9465 89 2 1 1 NUM ct-9465 89 3 . . PUNCT ct-9465 89 4 concannon concannon PROPN ct-9465 89 5 pw pw PROPN ct-9465 89 6 : : PUNCT ct-9465 89 7 canine canine PROPN ct-9465 89 8 pregnancy pregnancy NOUN ct-9465 89 9 : : PUNCT ct-9465 89 10 predicting predict VERB ct-9465 89 11 parturition parturition NOUN ct-9465 89 12 and and CCONJ ct-9465 89 13 timing time VERB ct-9465 89 14 events event NOUN ct-9465 89 15 of of ADP ct-9465 89 16 gestation gestation NOUN ct-9465 89 17 . . PUNCT ct-9465 90 1 ivis ivis PROPN ct-9465 90 2 2000 2000 NUM ct-9465 90 3 . . PUNCT ct-9465 91 1 2 2 X ct-9465 91 2 . . X ct-9465 91 3 furukawa furukawa PROPN ct-9465 91 4 s s PROPN ct-9465 91 5 , , PUNCT ct-9465 91 6 kuroda kuroda PROPN ct-9465 91 7 y y PROPN ct-9465 91 8 , , PUNCT ct-9465 91 9 sugiyama sugiyama NOUN ct-9465 91 10 a. a. NOUN ct-9465 91 11 a a DET ct-9465 91 12 comparison comparison NOUN ct-9465 91 13 of of ADP ct-9465 91 14 the the DET ct-9465 91 15 histological histological ADJ ct-9465 91 16 structure structure NOUN ct-9465 91 17 of of ADP ct-9465 91 18 the the DET ct-9465 91 19 placenta placenta NOUN ct-9465 91 20 in in ADP ct-9465 91 21 experimental experimental ADJ ct-9465 91 22 animals animal NOUN ct-9465 91 23 . . PUNCT ct-9465 92 1 j j PROPN ct-9465 92 2 toxicol toxicol PROPN ct-9465 92 3 pathol pathol VERB ct-9465 92 4 2014;27:11 2014;27:11 NUM ct-9465 92 5 - - SYM ct-9465 92 6 18 18 NUM ct-9465 92 7 . . NOUN ct-9465 93 1 3 3 X ct-9465 93 2 . . X ct-9465 93 3 green green PROPN ct-9465 93 4 ka ka PROPN ct-9465 93 5 , , PUNCT ct-9465 93 6 zarek zarek PROPN ct-9465 93 7 sm sm PROPN ct-9465 93 8 , , PUNCT ct-9465 93 9 catherino catherino PROPN ct-9465 93 10 wh wh PROPN ct-9465 93 11 : : PUNCT ct-9465 93 12 gynecologic gynecologic ADJ ct-9465 93 13 health health NOUN ct-9465 93 14 and and CCONJ ct-9465 93 15 disease disease NOUN ct-9465 93 16 in in ADP ct-9465 93 17 relation relation NOUN ct-9465 93 18 to to ADP ct-9465 93 19 the the DET ct-9465 93 20 microbiome microbiome NOUN ct-9465 93 21 of of ADP ct-9465 93 22 the the DET ct-9465 93 23 female female ADJ ct-9465 93 24 reproductive reproductive ADJ ct-9465 93 25 tract tract NOUN ct-9465 93 26 . . PUNCT ct-9465 94 1 fertil fertil AUX ct-9465 94 2 steril steril VERB ct-9465 94 3 2015;104:1351 2015;104:1351 NUM ct-9465 94 4 - - SYM ct-9465 94 5 1357 1357 NUM ct-9465 94 6 . . PUNCT ct-9465 95 1 4 4 X ct-9465 95 2 . . X ct-9465 95 3 wee wee PROPN ct-9465 95 4 ba ba PROPN ct-9465 95 5 , , PUNCT ct-9465 95 6 thomas thomas PROPN ct-9465 95 7 m m PROPN ct-9465 95 8 , , PUNCT ct-9465 95 9 sweeney sweeney PROPN ct-9465 95 10 el el PROPN ct-9465 95 11 , , PUNCT ct-9465 95 12 et et PROPN ct-9465 95 13 al al PROPN ct-9465 95 14 : : PUNCT ct-9465 95 15 a a DET ct-9465 95 16 retrospective retrospective ADJ ct-9465 95 17 pilot pilot NOUN ct-9465 95 18 study study NOUN ct-9465 95 19 to to PART ct-9465 95 20 determine determine VERB ct-9465 95 21 whether whether SCONJ ct-9465 95 22 the the DET ct-9465 95 23 reproductive reproductive ADJ ct-9465 95 24 tract tract NOUN ct-9465 95 25 microbiota microbiota NOUN ct-9465 95 26 differs differ VERB ct-9465 95 27 between between ADP ct-9465 95 28 women woman NOUN ct-9465 95 29 with with ADP ct-9465 95 30 a a DET ct-9465 95 31 history history NOUN ct-9465 95 32 of of ADP ct-9465 95 33 infertility infertility NOUN ct-9465 95 34 and and CCONJ ct-9465 95 35 fertile fertile ADJ ct-9465 95 36 women woman NOUN ct-9465 95 37 . . PUNCT ct-9465 96 1 aust aust PROPN ct-9465 96 2 n n PROPN ct-9465 96 3 z z PROPN ct-9465 96 4 j j PROPN ct-9465 96 5 obstet obstet NOUN ct-9465 96 6 gynaecol gynaecol PROPN ct-9465 96 7 2018;58:341 2018;58:341 NUM ct-9465 96 8 - - SYM ct-9465 96 9 348 348 NUM ct-9465 96 10 . . PUNCT ct-9465 96 11 5 5 NUM ct-9465 96 12 . . X ct-9465 96 13 benner benner PROPN ct-9465 96 14 m m PROPN ct-9465 96 15 , , PUNCT ct-9465 96 16 ferwerda ferwerda PROPN ct-9465 96 17 g g NOUN ct-9465 96 18 , , PUNCT ct-9465 96 19 joosten joosten VERB ct-9465 96 20 i i PRON ct-9465 96 21 , , PUNCT ct-9465 96 22 et et PROPN ct-9465 96 23 al al PROPN ct-9465 96 24 : : PUNCT ct-9465 96 25 how how SCONJ ct-9465 96 26 uterine uterine ADJ ct-9465 96 27 microbiota microbiota NOUN ct-9465 96 28 might might AUX ct-9465 96 29 be be AUX ct-9465 96 30 responsible responsible ADJ ct-9465 96 31 for for ADP ct-9465 96 32 a a DET ct-9465 96 33 receptive receptive ADJ ct-9465 96 34 , , PUNCT ct-9465 96 35 fertile fertile ADJ ct-9465 96 36 endometrium endometrium NOUN ct-9465 96 37 . . PUNCT ct-9465 97 1 hum hum PROPN ct-9465 97 2 reprod reprod PROPN ct-9465 97 3 update update VERB ct-9465 97 4 2018;24:393 2018;24:393 PROPN ct-9465 97 5 - - PUNCT ct-9465 97 6 415 415 NUM ct-9465 97 7 . . PUNCT ct-9465 98 1 6 6 NUM ct-9465 98 2 . . X ct-9465 98 3 verstraelen verstraelen PROPN ct-9465 98 4 h h PROPN ct-9465 98 5 , , PUNCT ct-9465 98 6 vilchez vilchez NOUN ct-9465 98 7 - - PUNCT ct-9465 98 8 vargas vargas NOUN ct-9465 98 9 r r NOUN ct-9465 98 10 , , PUNCT ct-9465 98 11 desimpel desimpel NOUN ct-9465 98 12 f f NOUN ct-9465 98 13 , , PUNCT ct-9465 98 14 et et PROPN ct-9465 98 15 al al PROPN ct-9465 98 16 : : PUNCT ct-9465 98 17 characterisation characterisation NOUN ct-9465 98 18 of of ADP ct-9465 98 19 the the DET ct-9465 98 20 human human ADJ ct-9465 98 21 uterine uterine ADJ ct-9465 98 22 microbiome microbiome NOUN ct-9465 98 23 in in ADP ct-9465 98 24 non non ADJ ct-9465 98 25 - - ADJ ct-9465 98 26 pregnant pregnant ADJ ct-9465 98 27 women woman NOUN ct-9465 98 28 through through ADP ct-9465 98 29 deep deep ADJ ct-9465 98 30 sequencing sequencing NOUN ct-9465 98 31 of of ADP ct-9465 98 32 the the DET ct-9465 98 33 v1 v1 NOUN ct-9465 98 34 - - PUNCT ct-9465 98 35 2 2 NUM ct-9465 98 36 region region NOUN ct-9465 98 37 of of ADP ct-9465 98 38 the the DET ct-9465 98 39 16s 16s PROPN ct-9465 98 40 rrna rrna PROPN ct-9465 98 41 gene gene NOUN ct-9465 98 42 . . PUNCT ct-9465 99 1 peerj peerj PROPN ct-9465 99 2 2016;4 2016;4 NUM ct-9465 99 3 : : PUNCT ct-9465 99 4 e1602 e1602 NOUN ct-9465 99 5 . . PUNCT ct-9465 100 1 7 7 X ct-9465 100 2 . . X ct-9465 100 3 lyman lyman PROPN ct-9465 100 4 cc cc PROPN ct-9465 100 5 , , PUNCT ct-9465 100 6 holyoak holyoak VERB ct-9465 100 7 gr gr ADP ct-9465 100 8 , , PUNCT ct-9465 100 9 meinkoth meinkoth NOUN ct-9465 100 10 k k NOUN ct-9465 100 11 , , PUNCT ct-9465 100 12 et et PROPN ct-9465 100 13 al al PROPN ct-9465 100 14 : : PUNCT ct-9465 100 15 canine canine VERB ct-9465 100 16 endometrial endometrial ADJ ct-9465 100 17 and and CCONJ ct-9465 100 18 vaginal vaginal ADJ ct-9465 100 19 microbiomes microbiome NOUN ct-9465 100 20 reveal reveal VERB ct-9465 100 21 distinct distinct ADJ ct-9465 100 22 and and CCONJ ct-9465 100 23 complex complex ADJ ct-9465 100 24 ecosystems ecosystem NOUN ct-9465 100 25 . . PUNCT ct-9465 101 1 plos plos PROPN ct-9465 101 2 one one NUM ct-9465 101 3 2019;14 2019;14 NUM ct-9465 101 4 : : PUNCT ct-9465 101 5 e0210157 e0210157 NOUN ct-9465 101 6 . . PROPN ct-9465 102 1 8 8 NUM ct-9465 102 2 . . X ct-9465 102 3 heil heil PROPN ct-9465 102 4 ba ba PROPN ct-9465 102 5 , , PUNCT ct-9465 102 6 thompson thompson PROPN ct-9465 102 7 sk sk PROPN ct-9465 102 8 , , PUNCT ct-9465 102 9 kearns kearn NOUN ct-9465 102 10 ta ta PROPN ct-9465 102 11 , , PUNCT ct-9465 102 12 et et PROPN ct-9465 102 13 al al PROPN ct-9465 102 14 : : PUNCT ct-9465 102 15 metagenetic metagenetic ADJ ct-9465 102 16 characterization characterization NOUN ct-9465 102 17 of of ADP ct-9465 102 18 the the DET ct-9465 102 19 resident resident ADJ ct-9465 102 20 equine equine NOUN ct-9465 102 21 uterine uterine ADJ ct-9465 102 22 microbiome microbiome NOUN ct-9465 102 23 using use VERB ct-9465 102 24 multiple multiple ADJ ct-9465 102 25 techniques technique NOUN ct-9465 102 26 . . PUNCT ct-9465 103 1 j j PROPN ct-9465 103 2 equine equine PROPN ct-9465 103 3 vet vet NOUN ct-9465 103 4 sci sci PROPN ct-9465 103 5 2018;66:111 2018;66:111 NUM ct-9465 103 6 . . NOUN ct-9465 104 1 9 9 NUM ct-9465 104 2 . . X ct-9465 104 3 holyoak holyoak PROPN ct-9465 104 4 gr gr PROPN ct-9465 104 5 , , PUNCT ct-9465 104 6 lyman lyman PROPN ct-9465 104 7 cc cc PROPN ct-9465 104 8 , , PUNCT ct-9465 104 9 wieneke wieneke PROPN ct-9465 104 10 x x NOUN ct-9465 104 11 , , PUNCT ct-9465 104 12 et et PROPN ct-9465 104 13 al al PROPN ct-9465 104 14 : : PUNCT ct-9465 104 15 the the DET ct-9465 104 16 equine equine ADJ ct-9465 104 17 endometrial endometrial ADJ ct-9465 104 18 microbiome microbiome NOUN ct-9465 104 19 . . PUNCT ct-9465 105 1 clinical clinical ADJ ct-9465 105 2 theriogenology theriogenology NOUN ct-9465 105 3 2018;10:273 2018;10:273 NUM ct-9465 105 4 . . PUNCT ct-9465 106 1 637 637 NUM ct-9465 106 2 clinical clinical ADJ ct-9465 106 3 theriogenology theriogenology NOUN ct-9465 106 4 • • NOUN ct-9465 106 5 volume volume NOUN ct-9465 106 6 11 11 NUM ct-9465 106 7 , , PUNCT ct-9465 106 8 number number NOUN ct-9465 106 9 4 4 NUM ct-9465 106 10 • • NOUN ct-9465 106 11 december december PROPN ct-9465 106 12 2019 2019 NUM ct-9465 106 13         SPACE ct-9465 106 14 10 10 NUM ct-9465 106 15 . . PUNCT ct-9465 107 1 doyle doyle PROPN ct-9465 107 2 rm rm PROPN ct-9465 107 3 , , PUNCT ct-9465 107 4 harris harris PROPN ct-9465 107 5 k k PROPN ct-9465 107 6 , , PUNCT ct-9465 107 7 kamiza kamiza PROPN ct-9465 107 8 s s PROPN ct-9465 107 9 , , PUNCT ct-9465 107 10 et et PROPN ct-9465 107 11 al al PROPN ct-9465 107 12 : : PUNCT ct-9465 107 13 bacterial bacterial ADJ ct-9465 107 14 communities community NOUN ct-9465 107 15 found find VERB ct-9465 107 16 in in ADP ct-9465 107 17 placental placental ADJ ct-9465 107 18 tissues tissue NOUN ct-9465 107 19 are be AUX ct-9465 107 20 associated associate VERB ct-9465 107 21 with with ADP ct-9465 107 22 severe severe ADJ ct-9465 107 23 chorioamnionitis chorioamnionitis NOUN ct-9465 107 24 and and CCONJ ct-9465 107 25 adverse adverse ADJ ct-9465 107 26 birth birth NOUN ct-9465 107 27 outcomes outcome NOUN ct-9465 107 28 . . PUNCT ct-9465 108 1 plos plos PROPN ct-9465 108 2 one one NUM ct-9465 108 3 2017;12 2017;12 NOUN ct-9465 108 4 : : PUNCT ct-9465 109 1 e0180167 e0180167 ADJ ct-9465 109 2 . . NOUN ct-9465 110 1 11 11 NUM ct-9465 110 2 . . PUNCT ct-9465 111 1 aagaard aagaard PROPN ct-9465 111 2 k k PROPN ct-9465 111 3 , , PUNCT ct-9465 111 4 ma ma PROPN ct-9465 111 5 j j PROPN ct-9465 111 6 , , PUNCT ct-9465 111 7 antony antony PROPN ct-9465 111 8 km km PROPN ct-9465 111 9 , , PUNCT ct-9465 111 10 et et PROPN ct-9465 111 11 al al PROPN ct-9465 111 12 : : PUNCT ct-9465 111 13 the the DET ct-9465 111 14 placenta placenta NOUN ct-9465 111 15 harbors harbor VERB ct-9465 111 16 a a DET ct-9465 111 17 unique unique ADJ ct-9465 111 18 microbiome microbiome NOUN ct-9465 111 19 . . PUNCT ct-9465 112 1 sci sci PROPN ct-9465 112 2 transl transl PROPN ct-9465 112 3 med med PROPN ct-9465 112 4 2014;6:237ra65 2014;6:237ra65 PROPN ct-9465 112 5 . . PUNCT ct-9465 113 1 12 12 NUM ct-9465 113 2 . . PUNCT ct-9465 114 1 xia xia PROPN ct-9465 114 2 yx yx PROPN ct-9465 114 3 , , PUNCT ct-9465 114 4 cornelius cornelius PROPN ct-9465 114 5 aj aj PROPN ct-9465 114 6 , , PUNCT ct-9465 114 7 donnelly donnelly PROPN ct-9465 114 8 cg cg NOUN ct-9465 114 9 , , PUNCT ct-9465 114 10 et et PROPN ct-9465 114 11 al al PROPN ct-9465 114 12 : : PUNCT ct-9465 114 13 metagenomic metagenomic ADJ ct-9465 114 14 analysis analysis NOUN ct-9465 114 15 of of ADP ct-9465 114 16 the the DET ct-9465 114 17 equine equine NOUN ct-9465 114 18 placental placental NOUN ct-9465 114 19 microbiome microbiome NOUN ct-9465 114 20 . . PUNCT ct-9465 115 1 clinical clinical ADJ ct-9465 115 2 theriogenology theriogenology NOUN ct-9465 115 3 2017;9:452 2017;9:452 NOUN ct-9465 115 4 . . PROPN ct-9465 115 5 13 13 NUM ct-9465 115 6 . . X ct-9465 115 7 canisso canisso PROPN ct-9465 115 8 if if SCONJ ct-9465 115 9 , , PUNCT ct-9465 115 10 stewart stewart PROPN ct-9465 115 11 j j PROPN ct-9465 115 12 , , PUNCT ct-9465 115 13 coutinho coutinho PROPN ct-9465 115 14 da da PROPN ct-9465 115 15 silva silva PROPN ct-9465 115 16 ma ma PROPN ct-9465 115 17 : : PUNCT ct-9465 115 18 endometritis endometritis NOUN ct-9465 115 19 : : PUNCT ct-9465 115 20 managing manage VERB ct-9465 115 21 persistent persistent ADJ ct-9465 115 22 post post ADJ ct-9465 115 23 - - ADJ ct-9465 115 24 breeding breeding ADJ ct-9465 115 25 endometritis endometritis NOUN ct-9465 115 26 . . PUNCT ct-9465 116 1 vet vet PROPN ct-9465 116 2 clin clin PROPN ct-9465 116 3 north north PROPN ct-9465 116 4 am be AUX ct-9465 116 5 equine equine NOUN ct-9465 116 6 pract pract NOUN ct-9465 116 7 2016;32:465 2016;32:465 PROPN ct-9465 116 8 - - SYM ct-9465 116 9 480 480 NUM ct-9465 116 10 . . PUNCT ct-9465 117 1 14 14 NUM ct-9465 117 2 . . PUNCT ct-9465 118 1 ferris ferris PROPN ct-9465 118 2 ra ra PROPN ct-9465 118 3 : : PUNCT ct-9465 119 1 endometritis endometritis NOUN ct-9465 119 2 : : PUNCT ct-9465 119 3 diagnostic diagnostic ADJ ct-9465 119 4 tools tool NOUN ct-9465 119 5 for for ADP ct-9465 119 6 infectious infectious ADJ ct-9465 119 7 endometritis endometritis NOUN ct-9465 119 8 . . PUNCT ct-9465 120 1 vet vet PROPN ct-9465 120 2 clin clin PROPN ct-9465 120 3 north north PROPN ct-9465 120 4 am be AUX ct-9465 120 5 equine equine NOUN ct-9465 120 6 pract pract NOUN ct-9465 120 7 2016 2016 NUM ct-9465 120 8 ; ; PUNCT ct-9465 120 9 32:481 32:481 NUM ct-9465 120 10 - - SYM ct-9465 120 11 498 498 NUM ct-9465 120 12 . . PUNCT ct-9465 121 1 15 15 NUM ct-9465 121 2 . . PUNCT ct-9465 121 3 fontaine fontaine PROPN ct-9465 121 4 e e PROPN ct-9465 121 5 , , PUNCT ct-9465 121 6 levy levy NOUN ct-9465 121 7 x x X ct-9465 121 8 , , PUNCT ct-9465 121 9 grellet grellet VERB ct-9465 121 10 a a PRON ct-9465 121 11 , , PUNCT ct-9465 121 12 et et PROPN ct-9465 121 13 al al PROPN ct-9465 121 14 : : PUNCT ct-9465 121 15 diagnosis diagnosis NOUN ct-9465 121 16 of of ADP ct-9465 121 17 endometritis endometritis NOUN ct-9465 121 18 in in ADP ct-9465 121 19 the the DET ct-9465 121 20 bitch bitch NOUN ct-9465 121 21 : : PUNCT ct-9465 121 22 a a DET ct-9465 121 23 new new ADJ ct-9465 121 24 approach approach NOUN ct-9465 121 25 . . PUNCT ct-9465 122 1 reprod reprod PROPN ct-9465 122 2 domest domest PROPN ct-9465 122 3 anim anim NOUN ct-9465 122 4 2009;44 2009;44 NUM ct-9465 122 5 suppl suppl ADJ ct-9465 122 6 2:196 2:196 NUM ct-9465 122 7 - - SYM ct-9465 122 8 199 199 NUM ct-9465 122 9 . . PUNCT ct-9465 123 1 16 16 NUM ct-9465 123 2 . . PUNCT ct-9465 124 1 lyman lyman PROPN ct-9465 124 2 cc cc PROPN ct-9465 124 3 , , PUNCT ct-9465 124 4 meinkoth meinkoth PROPN ct-9465 124 5 k k NOUN ct-9465 124 6 , , PUNCT ct-9465 124 7 desilva desilva NOUN ct-9465 124 8 u u NOUN ct-9465 124 9 , , PUNCT ct-9465 124 10 et et PROPN ct-9465 124 11 al al PROPN ct-9465 124 12 : : PUNCT ct-9465 124 13 16s 16s PROPN ct-9465 124 14 rdna rdna NOUN ct-9465 124 15 - - PUNCT ct-9465 124 16 based base VERB ct-9465 124 17 profiling profiling NOUN ct-9465 124 18 of of ADP ct-9465 124 19 canine canine ADJ ct-9465 124 20 reproductive reproductive ADJ ct-9465 124 21 tract tract NOUN ct-9465 124 22 microbiota microbiota NOUN ct-9465 124 23 reveals reveal VERB ct-9465 124 24 a a DET ct-9465 124 25 complex complex ADJ ct-9465 124 26 microbial microbial ADJ ct-9465 124 27 ecosystem ecosystem NOUN ct-9465 124 28 . . PUNCT ct-9465 125 1 clinical clinical ADJ ct-9465 125 2 theriogenology theriogenology NOUN ct-9465 125 3 2016;8:305 2016;8:305 PROPN ct-9465 125 4 . . PUNCT ct-9465 126 1 17 17 NUM ct-9465 126 2 . . PUNCT ct-9465 127 1 cornelius cornelius PROPN ct-9465 127 2 aj aj PROPN ct-9465 127 3 , , PUNCT ct-9465 127 4 bichalho bichalho PROPN ct-9465 127 5 rc rc PROPN ct-9465 127 6 , , PUNCT ct-9465 127 7 cheong cheong PROPN ct-9465 127 8 sh sh PROPN ct-9465 127 9 : : PUNCT ct-9465 127 10 the the DET ct-9465 127 11 canine canine NOUN ct-9465 127 12 vaginal vaginal ADJ ct-9465 127 13 microbiome microbiome NOUN ct-9465 127 14 and and CCONJ ct-9465 127 15 associations association NOUN ct-9465 127 16 with with ADP ct-9465 127 17 puppy puppy NOUN ct-9465 127 18 survival survival NOUN ct-9465 127 19 . . PUNCT ct-9465 128 1 clinical clinical ADJ ct-9465 128 2 theriogenology theriogenology NOUN ct-9465 128 3 2017;9:424 2017;9:424 NUM ct-9465 128 4 . . PROPN ct-9465 128 5 18 18 NUM ct-9465 128 6 . . PUNCT ct-9465 128 7 bracewell bracewell NOUN ct-9465 128 8 - - PUNCT ct-9465 128 9 milnes milne NOUN ct-9465 128 10 t t PROPN ct-9465 128 11 , , PUNCT ct-9465 128 12 saso saso PROPN ct-9465 128 13 s s PART ct-9465 128 14 , , PUNCT ct-9465 128 15 nikolaou nikolaou X ct-9465 128 16 d d PROPN ct-9465 128 17 , , PUNCT ct-9465 128 18 et et PROPN ct-9465 128 19 al al PROPN ct-9465 128 20 : : PUNCT ct-9465 128 21 investigating investigate VERB ct-9465 128 22 the the DET ct-9465 128 23 effect effect NOUN ct-9465 128 24 of of ADP ct-9465 128 25 an an DET ct-9465 128 26 abnormal abnormal ADJ ct-9465 128 27 cervico cervico NOUN ct-9465 128 28 - - PUNCT ct-9465 128 29 vaginal vaginal ADJ ct-9465 128 30 and and CCONJ ct-9465 128 31 endometrial endometrial ADJ ct-9465 128 32 microbiome microbiome NOUN ct-9465 128 33 on on ADP ct-9465 128 34 assisted assist VERB ct-9465 128 35 reproductive reproductive ADJ ct-9465 128 36 technologies technology NOUN ct-9465 128 37 : : PUNCT ct-9465 128 38 a a DET ct-9465 128 39 systematic systematic ADJ ct-9465 128 40 review review NOUN ct-9465 128 41 . . PUNCT ct-9465 129 1 am be AUX ct-9465 129 2 j j PROPN ct-9465 129 3 reprod reprod PROPN ct-9465 129 4 immunol immunol NOUN ct-9465 129 5 2018;80 2018;80 NUM ct-9465 129 6 : : PUNCT ct-9465 129 7 e13037 e13037 NOUN ct-9465 129 8 . . PUNCT ct-9465 130 1 638clinical 638clinical ADJ ct-9465 130 2 theriogenology theriogenology NOUN ct-9465 130 3 • • NOUN ct-9465 130 4 volume volume NOUN ct-9465 130 5 11 11 NUM ct-9465 130 6 , , PUNCT ct-9465 130 7 number number NOUN ct-9465 130 8 4 4 NUM ct-9465 130 9 • • NOUN ct-9465 130 10 december december PROPN ct-9465 130 11 2019 2019 NUM ct-9465 130 12 untitled untitled ADJ