id sid tid token lemma pos ct-9466 1 1 2019 2019 NUM ct-9466 1 2 reproductive reproductive ADJ ct-9466 1 3 microbiome microbiome NOUN ct-9466 1 4 alterations alteration NOUN ct-9466 1 5 : : PUNCT ct-9466 1 6 canine canine VERB ct-9466 1 7 pyometra pyometra NOUN ct-9466 1 8     SPACE ct-9466 1 9 reproductive reproductive ADJ ct-9466 1 10 microbiome microbiome NOUN ct-9466 1 11 alterations alteration NOUN ct-9466 1 12 : : PUNCT ct-9466 1 13 canine canine PROPN ct-9466 1 14 pyometra pyometra PROPN ct-9466 1 15 michelle michelle PROPN ct-9466 1 16 kutzler kutzler PROPN ct-9466 1 17 oregon oregon PROPN ct-9466 1 18 state state PROPN ct-9466 1 19 university university PROPN ct-9466 1 20 , , PUNCT ct-9466 1 21 corvallis corvallis PROPN ct-9466 1 22 , , PUNCT ct-9466 1 23 or or CCONJ ct-9466 1 24 abstract abstract ADJ ct-9466 1 25 pyometra pyometra NOUN ct-9466 1 26 is be AUX ct-9466 1 27 a a DET ct-9466 1 28 life life NOUN ct-9466 1 29 - - PUNCT ct-9466 1 30 threatening threaten VERB ct-9466 1 31 uterine uterine ADJ ct-9466 1 32 infection infection NOUN ct-9466 1 33 that that PRON ct-9466 1 34 affects affect VERB ct-9466 1 35 20 20 NUM ct-9466 1 36 25 25 NUM ct-9466 1 37 % % NOUN ct-9466 1 38 of of ADP ct-9466 1 39 reproductively reproductively ADV ct-9466 1 40 intact intact ADJ ct-9466 1 41 bitches bitch NOUN ct-9466 1 42 . . PUNCT ct-9466 2 1 canine canine PROPN ct-9466 2 2 pyometra pyometra PROPN ct-9466 2 3 is be AUX ct-9466 2 4 characterized characterize VERB ct-9466 2 5 by by ADP ct-9466 2 6 accumulation accumulation NOUN ct-9466 2 7 of of ADP ct-9466 2 8 leukocytes leukocyte NOUN ct-9466 2 9 and and CCONJ ct-9466 2 10 exudate exudate VERB ct-9466 2 11 within within ADP ct-9466 2 12 the the DET ct-9466 2 13 uterine uterine ADJ ct-9466 2 14 lumen luman NOUN ct-9466 2 15 . . PUNCT ct-9466 3 1 although although SCONJ ct-9466 3 2 exact exact ADJ ct-9466 3 3 temporal temporal ADJ ct-9466 3 4 and and CCONJ ct-9466 3 5 progressive progressive ADJ ct-9466 3 6 mechanisms mechanism NOUN ct-9466 3 7 underlying underlie VERB ct-9466 3 8 its its PRON ct-9466 3 9 pathogenesis pathogenesis NOUN ct-9466 3 10 are be AUX ct-9466 3 11 not not PART ct-9466 3 12 fully fully ADV ct-9466 3 13 understood understand VERB ct-9466 3 14 , , PUNCT ct-9466 3 15 a a DET ct-9466 3 16 combination combination NOUN ct-9466 3 17 of of ADP ct-9466 3 18 endocrine endocrine NOUN ct-9466 3 19 , , PUNCT ct-9466 3 20 structural structural ADJ ct-9466 3 21 , , PUNCT ct-9466 3 22 inflammatory inflammatory ADJ ct-9466 3 23 and and CCONJ ct-9466 3 24 bacterial bacterial ADJ ct-9466 3 25 factors factor NOUN ct-9466 3 26 are be AUX ct-9466 3 27 likely likely ADV ct-9466 3 28 involved involve VERB ct-9466 3 29 in in ADP ct-9466 3 30 most most ADJ ct-9466 3 31 cases case NOUN ct-9466 3 32 . . PUNCT ct-9466 4 1 pyometra pyometra NOUN ct-9466 4 2 develops develop VERB ct-9466 4 3 during during ADP ct-9466 4 4 luteal luteal ADJ ct-9466 4 5 phase phase NOUN ct-9466 4 6 ; ; PUNCT ct-9466 4 7 progesterone progesterone NOUN ct-9466 4 8 has have VERB ct-9466 4 9 a a DET ct-9466 4 10 key key ADJ ct-9466 4 11 role role NOUN ct-9466 4 12 in in ADP ct-9466 4 13 establishment establishment NOUN ct-9466 4 14 of of ADP ct-9466 4 15 infection infection NOUN ct-9466 4 16 with with ADP ct-9466 4 17 opportunistic opportunistic ADJ ct-9466 4 18 bacteria bacteria NOUN ct-9466 4 19 . . PUNCT ct-9466 5 1 cystic cystic ADJ ct-9466 5 2 endometrial endometrial ADJ ct-9466 5 3 hyperplasia hyperplasia NOUN ct-9466 5 4 results result NOUN ct-9466 5 5 from from ADP ct-9466 5 6 proliferation proliferation NOUN ct-9466 5 7 of of ADP ct-9466 5 8 endometrial endometrial ADJ ct-9466 5 9 glands gland NOUN ct-9466 5 10 and and CCONJ ct-9466 5 11 is be AUX ct-9466 5 12 a a DET ct-9466 5 13 predisposing predispose VERB ct-9466 5 14 factor factor NOUN ct-9466 5 15 for for ADP ct-9466 5 16 development development NOUN ct-9466 5 17 of of ADP ct-9466 5 18 pyometra pyometra ADJ ct-9466 5 19 . . PUNCT ct-9466 6 1 endometrial endometrial ADJ ct-9466 6 2 proliferation proliferation NOUN ct-9466 6 3 factors factor NOUN ct-9466 6 4 exacerbate exacerbate VERB ct-9466 6 5 uterine uterine ADJ ct-9466 6 6 innate innate ADJ ct-9466 6 7 immune immune ADJ ct-9466 6 8 responses response NOUN ct-9466 6 9 . . PUNCT ct-9466 7 1 whereas whereas SCONJ ct-9466 7 2 escherichia escherichia NOUN ct-9466 7 3 coli coli NOUN ct-9466 7 4 is be AUX ct-9466 7 5 the the DET ct-9466 7 6 most most ADV ct-9466 7 7 common common ADJ ct-9466 7 8 organism organism NOUN ct-9466 7 9 isolated isolate VERB ct-9466 7 10 in in ADP ct-9466 7 11 up up ADP ct-9466 7 12 to to PART ct-9466 7 13 90 90 NUM ct-9466 7 14 % % NOUN ct-9466 7 15 of of ADP ct-9466 7 16 cases case NOUN ct-9466 7 17 with with ADP ct-9466 7 18 a a DET ct-9466 7 19 positive positive ADJ ct-9466 7 20 culture culture NOUN ct-9466 7 21 , , PUNCT ct-9466 7 22 genes gene NOUN ct-9466 7 23 encoding encode VERB ct-9466 7 24 for for ADP ct-9466 7 25 adhesins adhesin NOUN ct-9466 7 26 , , PUNCT ct-9466 7 27 toxins toxin NOUN ct-9466 7 28 , , PUNCT ct-9466 7 29 and and CCONJ ct-9466 7 30 other other ADJ ct-9466 7 31 factors factor NOUN ct-9466 7 32 increase increase VERB ct-9466 7 33 virulence virulence NOUN ct-9466 7 34 of of ADP ct-9466 7 35 certain certain ADJ ct-9466 7 36 strains strain NOUN ct-9466 7 37 . . PUNCT ct-9466 8 1 a a DET ct-9466 8 2 presumptive presumptive ADJ ct-9466 8 3 diagnosis diagnosis NOUN ct-9466 8 4 of of ADP ct-9466 8 5 pyometra pyometra NOUN ct-9466 8 6 is be AUX ct-9466 8 7 based base VERB ct-9466 8 8 on on ADP ct-9466 8 9 clinical clinical ADJ ct-9466 8 10 signs sign NOUN ct-9466 8 11 and and CCONJ ct-9466 8 12 laboratory laboratory NOUN ct-9466 8 13 tests test NOUN ct-9466 8 14 , , PUNCT ct-9466 8 15 with with ADP ct-9466 8 16 a a DET ct-9466 8 17 confirmatory confirmatory NOUN ct-9466 8 18 diagnosis diagnosis NOUN ct-9466 8 19 based base VERB ct-9466 8 20 on on ADP ct-9466 8 21 b b NOUN ct-9466 8 22 - - PUNCT ct-9466 8 23 mode mode NOUN ct-9466 8 24 ultrasonography ultrasonography NOUN ct-9466 8 25 , , PUNCT ct-9466 8 26 with with ADP ct-9466 8 27 or or CCONJ ct-9466 8 28 without without ADP ct-9466 8 29 doppler doppler NOUN ct-9466 8 30 ultrasonography ultrasonography NOUN ct-9466 8 31 , , PUNCT ct-9466 8 32 detecting detect VERB ct-9466 8 33 an an DET ct-9466 8 34 enlarged enlarge VERB ct-9466 8 35 , , PUNCT ct-9466 8 36 fluid fluid NOUN ct-9466 8 37 - - PUNCT ct-9466 8 38 filled fill VERB ct-9466 8 39 uterus uterus NOUN ct-9466 8 40 with with ADP ct-9466 8 41 increased increase VERB ct-9466 8 42 blood blood NOUN ct-9466 8 43 flow flow NOUN ct-9466 8 44 . . PUNCT ct-9466 9 1 broad broad ADJ ct-9466 9 2 - - PUNCT ct-9466 9 3 spectrum spectrum NOUN ct-9466 9 4 antibiotics antibiotic NOUN ct-9466 9 5 with with ADP ct-9466 9 6 minimal minimal ADJ ct-9466 9 7 nephrotoxicity nephrotoxicity NOUN ct-9466 9 8 are be AUX ct-9466 9 9 needed need VERB ct-9466 9 10 to to PART ct-9466 9 11 prevent prevent VERB ct-9466 9 12 septicemia septicemia NOUN ct-9466 9 13 , , PUNCT ct-9466 9 14 but but CCONJ ct-9466 9 15 antibiotics antibiotic NOUN ct-9466 9 16 alone alone ADV ct-9466 9 17 will will AUX ct-9466 9 18 not not PART ct-9466 9 19 resolve resolve VERB ct-9466 9 20 pyometra pyometra NOUN ct-9466 9 21 . . PUNCT ct-9466 10 1 safest safe ADJ ct-9466 10 2 and and CCONJ ct-9466 10 3 most most ADV ct-9466 10 4 effective effective ADJ ct-9466 10 5 treatment treatment NOUN ct-9466 10 6 is be AUX ct-9466 10 7 surgical surgical ADJ ct-9466 10 8 removal removal NOUN ct-9466 10 9 of of ADP ct-9466 10 10 infected infected ADJ ct-9466 10 11 uterus uterus NOUN ct-9466 10 12 and and CCONJ ct-9466 10 13 ovaries ovary NOUN ct-9466 10 14 . . PUNCT ct-9466 11 1 medical medical ADJ ct-9466 11 2 management management NOUN ct-9466 11 3 of of ADP ct-9466 11 4 pyometra pyometra NOUN ct-9466 11 5 may may AUX ct-9466 11 6 be be AUX ct-9466 11 7 indicated indicate VERB ct-9466 11 8 to to PART ct-9466 11 9 improve improve VERB ct-9466 11 10 general general ADJ ct-9466 11 11 status status NOUN ct-9466 11 12 of of ADP ct-9466 11 13 the the DET ct-9466 11 14 bitch bitch NOUN ct-9466 11 15 prior prior ADV ct-9466 11 16 to to ADP ct-9466 11 17 surgery surgery NOUN ct-9466 11 18 or or CCONJ ct-9466 11 19 treatment treatment NOUN ct-9466 11 20 in in ADP ct-9466 11 21 valuable valuable ADJ ct-9466 11 22 breeding breeding NOUN ct-9466 11 23 bitches bitch NOUN ct-9466 11 24 . . PUNCT ct-9466 12 1 protocols protocol NOUN ct-9466 12 2 using use VERB ct-9466 12 3 prostaglandin prostaglandin VERB ct-9466 12 4 f2α f2α NOUN ct-9466 12 5 or or CCONJ ct-9466 12 6 aglepristone aglepristone NOUN ct-9466 12 7 are be AUX ct-9466 12 8 discussed discuss VERB ct-9466 12 9 in in ADP ct-9466 12 10 detail detail NOUN ct-9466 12 11 . . PUNCT ct-9466 13 1 keywords keyword NOUN ct-9466 13 2 : : PUNCT ct-9466 13 3 aglepristone aglepristone ADJ ct-9466 13 4 , , PUNCT ct-9466 13 5 cystic cystic ADJ ct-9466 13 6 endometrial endometrial ADJ ct-9466 13 7 hyperplasia hyperplasia NOUN ct-9466 13 8 , , PUNCT ct-9466 13 9 escherichia escherichia NOUN ct-9466 13 10 coli coli NOUN ct-9466 13 11 , , PUNCT ct-9466 13 12 prostaglandin prostaglandin ADJ ct-9466 13 13 f2α f2α NOUN ct-9466 13 14 , , PUNCT ct-9466 13 15 virulence virulence NOUN ct-9466 13 16 factors factor NOUN ct-9466 13 17 introduction introduction NOUN ct-9466 13 18 pyometra pyometra NOUN ct-9466 13 19 is be AUX ct-9466 13 20 a a DET ct-9466 13 21 life life NOUN ct-9466 13 22 - - PUNCT ct-9466 13 23 threatening threaten VERB ct-9466 13 24 bacterial bacterial ADJ ct-9466 13 25 infection infection NOUN ct-9466 13 26 of of ADP ct-9466 13 27 the the DET ct-9466 13 28 uterus uterus NOUN ct-9466 13 29 that that PRON ct-9466 13 30 affects affect VERB ct-9466 13 31 20 20 NUM ct-9466 13 32 25 25 NUM ct-9466 13 33 % % NOUN ct-9466 13 34 of of ADP ct-9466 13 35 reproductively reproductively ADV ct-9466 13 36 intact intact ADJ ct-9466 13 37 bitches.1 bitches.1 NOUN ct-9466 13 38 - - SYM ct-9466 13 39 5 5 NUM ct-9466 13 40 however however ADV ct-9466 13 41 , , PUNCT ct-9466 13 42 incidence incidence NOUN ct-9466 13 43 of of ADP ct-9466 13 44 pyometra pyometra NOUN ct-9466 13 45 may may AUX ct-9466 13 46 be be AUX ct-9466 13 47 > > X ct-9466 13 48 50 50 NUM ct-9466 13 49 % % NOUN ct-9466 13 50 in in ADP ct-9466 13 51 certain certain ADJ ct-9466 13 52 high high ADJ ct-9466 13 53 - - PUNCT ct-9466 13 54 risk risk NOUN ct-9466 13 55 breeds breed NOUN ct-9466 13 56 , , PUNCT ct-9466 13 57 indicating indicate VERB ct-9466 13 58 that that SCONJ ct-9466 13 59 there there PRON ct-9466 13 60 may may AUX ct-9466 13 61 be be AUX ct-9466 13 62 genetic genetic ADJ ct-9466 13 63 factors factor NOUN ct-9466 13 64 predisposing predispose VERB ct-9466 13 65 to to ADP ct-9466 13 66 development development NOUN ct-9466 13 67 of of ADP ct-9466 13 68 pyometra.2 pyometra.2 PROPN ct-9466 13 69 mean mean NOUN ct-9466 13 70 age age NOUN ct-9466 13 71 for for ADP ct-9466 13 72 pyometra pyometra ADJ ct-9466 13 73 diagnosis diagnosis NOUN ct-9466 13 74 in in ADP ct-9466 13 75 bitches bitch NOUN ct-9466 13 76 is be AUX ct-9466 13 77 7 7 NUM ct-9466 13 78 years year NOUN ct-9466 13 79 ( ( PUNCT ct-9466 13 80 range range NOUN ct-9466 13 81 : : PUNCT ct-9466 13 82 4 4 NUM ct-9466 13 83 months month NOUN ct-9466 13 84 to to ADP ct-9466 13 85 18 18 NUM ct-9466 13 86 years).2 years).2 PROPN ct-9466 13 87 etiopathogenesis etiopathogenesis NOUN ct-9466 13 88 canine canine NOUN ct-9466 13 89 pyometra pyometra NOUN ct-9466 13 90 is be AUX ct-9466 13 91 characterized characterize VERB ct-9466 13 92 by by ADP ct-9466 13 93 an an DET ct-9466 13 94 accumulation accumulation NOUN ct-9466 13 95 of of ADP ct-9466 13 96 leukocytes leukocyte NOUN ct-9466 13 97 and and CCONJ ct-9466 13 98 exudate exudate VERB ct-9466 13 99 within within ADP ct-9466 13 100 uterine uterine ADJ ct-9466 13 101 lumen luman NOUN ct-9466 13 102 . . PUNCT ct-9466 14 1 although although SCONJ ct-9466 14 2 exact exact ADJ ct-9466 14 3 temporal temporal ADJ ct-9466 14 4 and and CCONJ ct-9466 14 5 progressive progressive ADJ ct-9466 14 6 mechanisms mechanism NOUN ct-9466 14 7 underlying underlie VERB ct-9466 14 8 pathogenesis pathogenesis NOUN ct-9466 14 9 are be AUX ct-9466 14 10 not not PART ct-9466 14 11 fully fully ADV ct-9466 14 12 understood understand VERB ct-9466 14 13 , , PUNCT ct-9466 14 14 a a DET ct-9466 14 15 combination combination NOUN ct-9466 14 16 of of ADP ct-9466 14 17 endocrine endocrine NOUN ct-9466 14 18 , , PUNCT ct-9466 14 19 structural structural ADJ ct-9466 14 20 , , PUNCT ct-9466 14 21 inflammatory inflammatory ADJ ct-9466 14 22 and and CCONJ ct-9466 14 23 bacterial bacterial ADJ ct-9466 14 24 factors factor NOUN ct-9466 14 25 are be AUX ct-9466 14 26 likely likely ADV ct-9466 14 27 involved involve VERB ct-9466 14 28 in in ADP ct-9466 14 29 most most ADJ ct-9466 14 30 cases case NOUN ct-9466 14 31 . . PUNCT ct-9466 15 1 endocrine endocrine ADJ ct-9466 15 2 factors factor NOUN ct-9466 15 3 pyometra pyometra NOUN ct-9466 15 4 develops develop VERB ct-9466 15 5 during during ADP ct-9466 15 6 luteal luteal ADJ ct-9466 15 7 phase phase NOUN ct-9466 15 8 ; ; PUNCT ct-9466 15 9 progesterone progesterone NOUN ct-9466 15 10 has have VERB ct-9466 15 11 a a DET ct-9466 15 12 key key ADJ ct-9466 15 13 role role NOUN ct-9466 15 14 for for ADP ct-9466 15 15 establishment establishment NOUN ct-9466 15 16 of of ADP ct-9466 15 17 infection infection NOUN ct-9466 15 18 with with ADP ct-9466 15 19 opportunistic opportunistic ADJ ct-9466 15 20 bacteria bacteria NOUN ct-9466 15 21 . . PUNCT ct-9466 16 1 during during ADP ct-9466 16 2 diestrus diestrus NOUN ct-9466 16 3 , , PUNCT ct-9466 16 4 progesterone progesterone NOUN ct-9466 16 5 induces induce VERB ct-9466 16 6 endometrial endometrial ADJ ct-9466 16 7 proliferation proliferation NOUN ct-9466 16 8 , , PUNCT ct-9466 16 9 endometrial endometrial ADJ ct-9466 16 10 gland gland NOUN ct-9466 16 11 secretion secretion NOUN ct-9466 16 12 , , PUNCT ct-9466 16 13 myometrial myometrial ADJ ct-9466 16 14 quiescence quiescence NOUN ct-9466 16 15 and and CCONJ ct-9466 16 16 cervical cervical ADJ ct-9466 16 17 closure.6 closure.6 PROPN ct-9466 16 18 - - PUNCT ct-9466 16 19 7 7 NUM ct-9466 16 20 progesterone progesterone NOUN ct-9466 16 21 not not PART ct-9466 16 22 only only ADV ct-9466 16 23 inhibits inhibit VERB ct-9466 16 24 endometrial endometrial ADJ ct-9466 16 25 bactericidal bactericidal ADJ ct-9466 16 26 activity activity NOUN ct-9466 16 27 , , PUNCT ct-9466 16 28 it it PRON ct-9466 16 29 also also ADV ct-9466 16 30 specifically specifically ADV ct-9466 16 31 increase increase VERB ct-9466 16 32 the the DET ct-9466 16 33 affinity affinity NOUN ct-9466 16 34 of of ADP ct-9466 16 35 endometrium endometrium NOUN ct-9466 16 36 to to ADP ct-9466 16 37 escherichia escherichia NOUN ct-9466 16 38 coli coli NOUN ct-9466 16 39 ( ( PUNCT ct-9466 16 40 e. e. PROPN ct-9466 16 41 coli).8 coli).8 PROPN ct-9466 16 42 in in ADP ct-9466 16 43 addition addition NOUN ct-9466 16 44 , , PUNCT ct-9466 16 45 repeated repeat VERB ct-9466 16 46 exposure exposure NOUN ct-9466 16 47 to to ADP ct-9466 16 48 endogenous endogenous ADJ ct-9466 16 49 and/or and/or CCONJ ct-9466 16 50 exogenous exogenous ADJ ct-9466 16 51 progestogens progestogen NOUN ct-9466 16 52 has have VERB ct-9466 16 53 an an DET ct-9466 16 54 important important ADJ ct-9466 16 55 role role NOUN ct-9466 16 56 in in ADP ct-9466 16 57 pathogenesis pathogenesis NOUN ct-9466 16 58 of of ADP ct-9466 16 59 cystic cystic ADJ ct-9466 16 60 endometrial endometrial ADJ ct-9466 16 61 hyperplasia hyperplasia NOUN ct-9466 16 62 , , PUNCT ct-9466 16 63 which which PRON ct-9466 16 64 also also ADV ct-9466 16 65 has have VERB ct-9466 16 66 a a DET ct-9466 16 67 key key ADJ ct-9466 16 68 role role NOUN ct-9466 16 69 in in ADP ct-9466 16 70 development development NOUN ct-9466 16 71 of of ADP ct-9466 16 72 pyometra.9 pyometra.9 PROPN ct-9466 16 73 - - ADJ ct-9466 16 74 12 12 NUM ct-9466 16 75 structural structural ADJ ct-9466 16 76 factors factor NOUN ct-9466 16 77 cystic cystic ADJ ct-9466 16 78 endometrial endometrial ADJ ct-9466 16 79 hyperplasia hyperplasia NOUN ct-9466 16 80 ( ( PUNCT ct-9466 16 81 ceh ceh NOUN ct-9466 16 82 ) ) PUNCT ct-9466 16 83 results result NOUN ct-9466 16 84 from from ADP ct-9466 16 85 proliferation proliferation NOUN ct-9466 16 86 of of ADP ct-9466 16 87 endometrial endometrial ADJ ct-9466 16 88 glands gland NOUN ct-9466 16 89 and and CCONJ ct-9466 16 90 subsequent subsequent ADJ ct-9466 16 91 endometrial endometrial ADJ ct-9466 16 92 cyst cyst NOUN ct-9466 16 93 formation formation NOUN ct-9466 16 94 . . PUNCT ct-9466 17 1 ceh ceh PROPN ct-9466 17 2 is be AUX ct-9466 17 3 accompanied accompany VERB ct-9466 17 4 by by ADP ct-9466 17 5 severe severe ADJ ct-9466 17 6 changes change NOUN ct-9466 17 7 in in ADP ct-9466 17 8 endometrial endometrial ADJ ct-9466 17 9 cell cell NOUN ct-9466 17 10 proliferation proliferation NOUN ct-9466 17 11 and and CCONJ ct-9466 17 12 apoptosis apoptosis NOUN ct-9466 17 13 , , PUNCT ct-9466 17 14 coinciding coincide VERB ct-9466 17 15 with with ADP ct-9466 17 16 dysregulation dysregulation NOUN ct-9466 17 17 in in ADP ct-9466 17 18 expression expression NOUN ct-9466 17 19 of of ADP ct-9466 17 20 apoptosis apoptosis ADJ ct-9466 17 21 regulatory regulatory ADJ ct-9466 17 22 proteins protein NOUN ct-9466 17 23 ( ( PUNCT ct-9466 17 24 e.g. e.g. ADV ct-9466 17 25 bcl2 bcl2 NOUN ct-9466 17 26 , , PUNCT ct-9466 17 27 bax).13 bax).13 PRON ct-9466 17 28 these these DET ct-9466 17 29 alterations alteration NOUN ct-9466 17 30 cause cause VERB ct-9466 17 31 excessive excessive ADJ ct-9466 17 32 proliferation proliferation NOUN ct-9466 17 33 , , PUNCT ct-9466 17 34 combined combine VERB ct-9466 17 35 with with ADP ct-9466 17 36 deregulation deregulation NOUN ct-9466 17 37 of of ADP ct-9466 17 38 639 639 NUM ct-9466 17 39 clinical clinical ADJ ct-9466 17 40 theriogenology theriogenology NOUN ct-9466 17 41 • • NOUN ct-9466 17 42 volume volume NOUN ct-9466 17 43 11 11 NUM ct-9466 17 44 , , PUNCT ct-9466 17 45 number number NOUN ct-9466 17 46 4 4 NUM ct-9466 17 47 • • NOUN ct-9466 17 48 december december PROPN ct-9466 17 49 2019 2019 NUM ct-9466 17 50     SPACE ct-9466 17 51 apoptosis apoptosis NOUN ct-9466 17 52 , , PUNCT ct-9466 17 53 which which PRON ct-9466 17 54 then then ADV ct-9466 17 55 causes cause VERB ct-9466 17 56 insufficient insufficient ADJ ct-9466 17 57 endometrial endometrial ADJ ct-9466 17 58 regeneration.13 regeneration.13 NOUN ct-9466 17 59 role role NOUN ct-9466 17 60 of of ADP ct-9466 17 61 progestogens progestogen NOUN ct-9466 17 62 in in ADP ct-9466 17 63 pathogenesis pathogenesis NOUN ct-9466 17 64 of of ADP ct-9466 17 65 ceh ceh PROPN ct-9466 17 66 is be AUX ct-9466 17 67 exacerbated exacerbate VERB ct-9466 17 68 by by ADP ct-9466 17 69 estradiol estradiol PROPN ct-9466 17 70 17β.6 17β.6 PROPN ct-9466 17 71 - - SYM ct-9466 17 72 7 7 NUM ct-9466 17 73 ceh ceh PROPN ct-9466 17 74 is be AUX ct-9466 17 75 the the DET ct-9466 17 76 most most ADV ct-9466 17 77 common common ADJ ct-9466 17 78 uterine uterine ADJ ct-9466 17 79 disease disease NOUN ct-9466 17 80 in in ADP ct-9466 17 81 dogs.14 dogs.14 NOUN ct-9466 17 82 incidence incidence NOUN ct-9466 17 83 of of ADP ct-9466 17 84 ceh ceh PROPN ct-9466 17 85 increases increase VERB ct-9466 17 86 with with ADP ct-9466 17 87 age age NOUN ct-9466 17 88 from from ADP ct-9466 17 89 < < X ct-9466 17 90 4 4 NUM ct-9466 17 91 % % NOUN ct-9466 17 92 in in ADP ct-9466 17 93 bitches bitch NOUN ct-9466 17 94 under under ADP ct-9466 17 95 3 3 NUM ct-9466 17 96 years year NOUN ct-9466 17 97 of of ADP ct-9466 17 98 age age NOUN ct-9466 17 99 to to ADP ct-9466 17 100 > > SYM ct-9466 17 101 50 50 NUM ct-9466 17 102 % % NOUN ct-9466 17 103 in in ADP ct-9466 17 104 bitches bitch NOUN ct-9466 17 105 by by ADP ct-9466 17 106 7 7 NUM ct-9466 17 107 years.15 years.15 NOUN ct-9466 17 108 it it PRON ct-9466 17 109 is be AUX ct-9466 17 110 important important ADJ ct-9466 17 111 to to PART ct-9466 17 112 note note VERB ct-9466 17 113 that that SCONJ ct-9466 17 114 not not PART ct-9466 17 115 all all DET ct-9466 17 116 cases case NOUN ct-9466 17 117 of of ADP ct-9466 17 118 pyometra pyometra NOUN ct-9466 17 119 involve involve VERB ct-9466 17 120 ceh ceh PROPN ct-9466 17 121 . . PROPN ct-9466 17 122 normal normal ADJ ct-9466 17 123 uterine uterine ADJ ct-9466 17 124 defence defence NOUN ct-9466 17 125 mechanisms mechanism NOUN ct-9466 17 126 against against ADP ct-9466 17 127 pyometra pyometra NOUN ct-9466 17 128 include include VERB ct-9466 17 129 : : PUNCT ct-9466 17 130 ( ( PUNCT ct-9466 17 131 1 1 X ct-9466 17 132 ) ) PUNCT ct-9466 17 133 a a DET ct-9466 17 134 potent potent ADJ ct-9466 17 135 local local ADJ ct-9466 17 136 immune immune ADJ ct-9466 17 137 response response NOUN ct-9466 17 138 with with ADP ct-9466 17 139 leukocytes leukocyte NOUN ct-9466 17 140 and and CCONJ ct-9466 17 141 antibodies antibodie VERB ct-9466 17 142 , , PUNCT ct-9466 17 143 ( ( PUNCT ct-9466 17 144 2 2 X ct-9466 17 145 ) ) PUNCT ct-9466 17 146 well well ADV ct-9466 17 147 - - PUNCT ct-9466 17 148 regulated regulate VERB ct-9466 17 149 endometrial endometrial ADJ ct-9466 17 150 secretions secretion NOUN ct-9466 17 151 and and CCONJ ct-9466 17 152 ( ( PUNCT ct-9466 17 153 3 3 X ct-9466 17 154 ) ) PUNCT ct-9466 17 155 myometrial myometrial ADJ ct-9466 17 156 contractions.7 contractions.7 NOUN ct-9466 17 157 however however ADV ct-9466 17 158 , , PUNCT ct-9466 17 159 functional functional ADJ ct-9466 17 160 patency patency NOUN ct-9466 17 161 of of ADP ct-9466 17 162 the the DET ct-9466 17 163 cervix cervix NOUN ct-9466 17 164 also also ADV ct-9466 17 165 has have VERB ct-9466 17 166 an an DET ct-9466 17 167 important important ADJ ct-9466 17 168 structural structural ADJ ct-9466 17 169 role role NOUN ct-9466 17 170 . . PUNCT ct-9466 18 1 with with ADP ct-9466 18 2 a a DET ct-9466 18 3 functionally functionally ADV ct-9466 18 4 patent patent NOUN ct-9466 18 5 cervix cervix NOUN ct-9466 18 6 ( ( PUNCT ct-9466 18 7 open open ADJ ct-9466 18 8 pyometra pyometra NOUN ct-9466 18 9 ) ) PUNCT ct-9466 18 10 , , PUNCT ct-9466 18 11 mucopurulent mucopurulent NOUN ct-9466 18 12 to to PART ct-9466 18 13 hemorrhagic hemorrhagic VERB ct-9466 18 14 exudate exudate VERB ct-9466 18 15 can can AUX ct-9466 18 16 exit exit VERB ct-9466 18 17 the the DET ct-9466 18 18 uterus uterus NOUN ct-9466 18 19 . . PUNCT ct-9466 19 1 when when SCONJ ct-9466 19 2 cervix cervix NOUN ct-9466 19 3 is be AUX ct-9466 19 4 not not PART ct-9466 19 5 patent patent NOUN ct-9466 19 6 ( ( PUNCT ct-9466 19 7 closed closed ADJ ct-9466 19 8 pyometra pyometra NOUN ct-9466 19 9 ) ) PUNCT ct-9466 19 10 , , PUNCT ct-9466 19 11 bacterial bacterial ADJ ct-9466 19 12 laden laden NOUN ct-9466 19 13 exudate exudate NOUN ct-9466 19 14 accumulates accumulate VERB ct-9466 19 15 within within ADP ct-9466 19 16 uterine uterine ADJ ct-9466 19 17 lumen luman NOUN ct-9466 19 18 , , PUNCT ct-9466 19 19 resulting result VERB ct-9466 19 20 in in ADP ct-9466 19 21 endometrial endometrial ADJ ct-9466 19 22 atrophy.16 atrophy.16 PROPN ct-9466 19 23 closed close VERB ct-9466 19 24 pyometras pyometra NOUN ct-9466 19 25 are be AUX ct-9466 19 26 associated associate VERB ct-9466 19 27 with with ADP ct-9466 19 28 more more ADV ct-9466 19 29 severe severe ADJ ct-9466 19 30 illness illness NOUN ct-9466 19 31 compared compare VERB ct-9466 19 32 to to ADP ct-9466 19 33 open open ADJ ct-9466 19 34 pyometras pyometra NOUN ct-9466 19 35 , , PUNCT ct-9466 19 36 but but CCONJ ct-9466 19 37 not not PART ct-9466 19 38 poorer poor ADJ ct-9466 19 39 outcomes outcome NOUN ct-9466 19 40 as as SCONJ ct-9466 19 41 measured measure VERB ct-9466 19 42 by by ADP ct-9466 19 43 postoperative postoperative ADJ ct-9466 19 44 hospitalization.3 hospitalization.3 NOUN ct-9466 19 45 with with ADP ct-9466 19 46 respect respect NOUN ct-9466 19 47 to to ADP ct-9466 19 48 incidence incidence NOUN ct-9466 19 49 , , PUNCT ct-9466 19 50 open open ADJ ct-9466 19 51 pyometra pyometra NOUN ct-9466 19 52 occurs occur VERB ct-9466 19 53 more more ADV ct-9466 19 54 commonly commonly ADV ct-9466 19 55 ( ( PUNCT ct-9466 19 56 65 65 NUM ct-9466 19 57 75 75 NUM ct-9466 19 58 % % NOUN ct-9466 19 59 ) ) PUNCT ct-9466 19 60 than than ADP ct-9466 19 61 closed close VERB ct-9466 19 62 pyometra pyometra NOUN ct-9466 19 63 ( ( PUNCT ct-9466 19 64 25 25 NUM ct-9466 19 65 35%).3,5 35%).3,5 NUM ct-9466 19 66 inflammatory inflammatory ADJ ct-9466 19 67 factors factor NOUN ct-9466 19 68 lipopolysaccharide lipopolysaccharide ADV ct-9466 19 69 ( ( PUNCT ct-9466 19 70 lps lps PROPN ct-9466 19 71 ) ) PUNCT ct-9466 19 72 from from ADP ct-9466 19 73 bacterial bacterial ADJ ct-9466 19 74 cell cell NOUN ct-9466 19 75 walls wall NOUN ct-9466 19 76 elicits elicit VERB ct-9466 19 77 a a DET ct-9466 19 78 strong strong ADJ ct-9466 19 79 inflammatory inflammatory ADJ ct-9466 19 80 response response NOUN ct-9466 19 81 . . PUNCT ct-9466 20 1 uterine uterine ADJ ct-9466 20 2 inflammation inflammation NOUN ct-9466 20 3 in in ADP ct-9466 20 4 response response NOUN ct-9466 20 5 to to ADP ct-9466 20 6 lps lps PROPN ct-9466 20 7 is be AUX ct-9466 20 8 associated associate VERB ct-9466 20 9 with with ADP ct-9466 20 10 upregulation upregulation NOUN ct-9466 20 11 of of ADP ct-9466 20 12 endometrial endometrial ADJ ct-9466 20 13 genes gene NOUN ct-9466 20 14 related relate VERB ct-9466 20 15 to to ADP ct-9466 20 16 the the DET ct-9466 20 17 innate innate ADJ ct-9466 20 18 immune immune ADJ ct-9466 20 19 response response NOUN ct-9466 20 20 . . PUNCT ct-9466 21 1 in in ADP ct-9466 21 2 response response NOUN ct-9466 21 3 to to ADP ct-9466 21 4 this this DET ct-9466 21 5 inflammation inflammation NOUN ct-9466 21 6 , , PUNCT ct-9466 21 7 endometrial endometrial ADJ ct-9466 21 8 proliferation proliferation NOUN ct-9466 21 9 factors factor NOUN ct-9466 21 10 exacerbate exacerbate VERB ct-9466 21 11 the the DET ct-9466 21 12 inflammatory inflammatory ADJ ct-9466 21 13 reaction.17 reaction.17 NOUN ct-9466 21 14 these these DET ct-9466 21 15 factors factor NOUN ct-9466 21 16 are be AUX ct-9466 21 17 : : PUNCT ct-9466 21 18 ( ( PUNCT ct-9466 21 19 1 1 X ct-9466 21 20 ) ) PUNCT ct-9466 21 21 insulin insulin NOUN ct-9466 21 22 - - PUNCT ct-9466 21 23 like like ADJ ct-9466 21 24 growth growth NOUN ct-9466 21 25 factor factor NOUN ct-9466 21 26 ( ( PUNCT ct-9466 21 27 igf1 igf1 PROPN ct-9466 21 28 ) ) PUNCT ct-9466 21 29 , , PUNCT ct-9466 21 30 ( ( PUNCT ct-9466 21 31 2 2 X ct-9466 21 32 ) ) PUNCT ct-9466 21 33 endometrial endometrial ADJ ct-9466 21 34 remodelling remodelling NOUN ct-9466 21 35 ( ( PUNCT ct-9466 21 36 via via ADP ct-9466 21 37 matrix matrix NOUN ct-9466 21 38 metalloproteinases metalloproteinase NOUN ct-9466 21 39 ) ) PUNCT ct-9466 21 40 and and CCONJ ct-9466 21 41 ( ( PUNCT ct-9466 21 42 3 3 X ct-9466 21 43 ) ) PUNCT ct-9466 21 44 inflammatory inflammatory ADJ ct-9466 21 45 response response NOUN ct-9466 21 46 genes gene NOUN ct-9466 21 47 ( ( PUNCT ct-9466 21 48 e.g. e.g. ADV ct-9466 21 49 chemokine chemokine ADJ ct-9466 21 50 ligand ligand NOUN ct-9466 21 51 2 2 NUM ct-9466 21 52 ( ( PUNCT ct-9466 21 53 cxcl2 cxcl2 PROPN ct-9466 21 54 ) ) PUNCT ct-9466 21 55 , , PUNCT ct-9466 21 56 secretory secretory ADJ ct-9466 21 57 leukocyte leukocyte NOUN ct-9466 21 58 peptidase peptidase NOUN ct-9466 21 59 inhibitor inhibitor NOUN ct-9466 21 60 ( ( PUNCT ct-9466 21 61 spli spli NOUN ct-9466 21 62 ) ) PUNCT ct-9466 21 63 ) ) PUNCT ct-9466 21 64 . . PUNCT ct-9466 22 1 based base VERB ct-9466 22 2 on on ADP ct-9466 22 3 global global ADJ ct-9466 22 4 endometrial endometrial ADJ ct-9466 22 5 transcriptomic transcriptomic ADJ ct-9466 22 6 profiling profiling NOUN ct-9466 22 7 by by ADP ct-9466 22 8 microarray microarray NOUN ct-9466 22 9 , , PUNCT ct-9466 22 10 many many ADJ ct-9466 22 11 genes gene NOUN ct-9466 22 12 are be AUX ct-9466 22 13 upregulated upregulate VERB ct-9466 22 14 ~ ~ PUNCT ct-9466 22 15 10 10 NUM ct-9466 22 16 77 77 NUM ct-9466 22 17 times time NOUN ct-9466 22 18 in in ADP ct-9466 22 19 uteruses uterus NOUN ct-9466 22 20 of of ADP ct-9466 22 21 bitches bitch NOUN ct-9466 22 22 with with ADP ct-9466 22 23 pyometra.18 pyometra.18 ADJ ct-9466 22 24 pyometra pyometra NOUN ct-9466 22 25 can can AUX ct-9466 22 26 be be AUX ct-9466 22 27 histologically histologically ADV ct-9466 22 28 classified classify VERB ct-9466 22 29 as as ADP ct-9466 22 30 either either CCONJ ct-9466 22 31 hyperplastic hyperplastic ADJ ct-9466 22 32 or or CCONJ ct-9466 22 33 atrophic.19 atrophic.19 NOUN ct-9466 22 34 endometrial endometrial ADJ ct-9466 22 35 thickness thickness NOUN ct-9466 22 36 and and CCONJ ct-9466 22 37 ratio ratio NOUN ct-9466 22 38 of of ADP ct-9466 22 39 endometrial endometrial NOUN ct-9466 22 40 to to ADP ct-9466 22 41 myometrial myometrial ADJ ct-9466 22 42 thickness thickness NOUN ct-9466 22 43 are be AUX ct-9466 22 44 increased increase VERB ct-9466 22 45 3 3 NUM ct-9466 22 46 - - NOUN ct-9466 22 47 fold fold ADJ ct-9466 22 48 in in ADP ct-9466 22 49 hyperplastic hyperplastic ADJ ct-9466 22 50 pyometra pyometra NOUN ct-9466 22 51 compared compare VERB ct-9466 22 52 to to ADP ct-9466 22 53 a a DET ct-9466 22 54 normal normal ADJ ct-9466 22 55 uterus.19 uterus.19 NOUN ct-9466 22 56 histologically histologically NOUN ct-9466 22 57 , , PUNCT ct-9466 22 58 a a DET ct-9466 22 59 uterus uterus NOUN ct-9466 22 60 associated associate VERB ct-9466 22 61 with with ADP ct-9466 22 62 atrophic atrophic ADJ ct-9466 22 63 pyometra pyometra NOUN ct-9466 22 64 has have VERB ct-9466 22 65 severe severe ADJ ct-9466 22 66 thinning thinning NOUN ct-9466 22 67 of of ADP ct-9466 22 68 endometrial endometrial ADJ ct-9466 22 69 mucosa mucosa NOUN ct-9466 22 70 ( ( PUNCT ct-9466 22 71 with with ADP ct-9466 22 72 thin thin ADJ ct-9466 22 73 cuboidal cuboidal ADJ ct-9466 22 74 epithelial epithelial ADJ ct-9466 22 75 cells cell NOUN ct-9466 22 76 ) ) PUNCT ct-9466 22 77 with with ADP ct-9466 22 78 concurrent concurrent ADJ ct-9466 22 79 hypertrophy hypertrophy NOUN ct-9466 22 80 of of ADP ct-9466 22 81 myometrium.19 myometrium.19 NOUN ct-9466 22 82 these these DET ct-9466 22 83 2 2 NUM ct-9466 22 84 forms form NOUN ct-9466 22 85 have have VERB ct-9466 22 86 differential differential ADJ ct-9466 22 87 regulation regulation NOUN ct-9466 22 88 of of ADP ct-9466 22 89 inflammatory inflammatory ADJ ct-9466 22 90 cytokines cytokine NOUN ct-9466 22 91 and and CCONJ ct-9466 22 92 enzymes enzyme NOUN ct-9466 22 93 in in ADP ct-9466 22 94 the the DET ct-9466 22 95 prostaglandin prostaglandin NOUN ct-9466 22 96 synthetic synthetic ADJ ct-9466 22 97 pathway pathway NOUN ct-9466 22 98 in in ADP ct-9466 22 99 the the DET ct-9466 22 100 endometrium.19 endometrium.19 NOUN ct-9466 22 101 for for ADP ct-9466 22 102 example example NOUN ct-9466 22 103 , , PUNCT ct-9466 22 104 a a DET ct-9466 22 105 relative relative ADJ ct-9466 22 106 fold fold ADJ ct-9466 22 107 increase increase NOUN ct-9466 22 108 in in ADP ct-9466 22 109 interleukin interleukin NOUN ct-9466 22 110 8 8 NUM ct-9466 22 111 ( ( PUNCT ct-9466 22 112 il8 il8 PROPN ct-9466 22 113 ) ) PUNCT ct-9466 22 114 of of ADP ct-9466 22 115 1.82 1.82 NUM ct-9466 22 116 times time NOUN ct-9466 22 117 occurs occur VERB ct-9466 22 118 in in ADP ct-9466 22 119 atrophic atrophic ADJ ct-9466 22 120 pyometra pyometra NOUN ct-9466 22 121 compared compare VERB ct-9466 22 122 to to ADP ct-9466 22 123 hyperplastic hyperplastic ADJ ct-9466 22 124 pyometra.19 pyometra.19 NOUN ct-9466 22 125 in in ADP ct-9466 22 126 addition addition NOUN ct-9466 22 127 , , PUNCT ct-9466 22 128 expression expression NOUN ct-9466 22 129 of of ADP ct-9466 22 130 cyclooxygenase cyclooxygenase NOUN ct-9466 22 131 type-2 type-2 NUM ct-9466 22 132 ( ( PUNCT ct-9466 22 133 cox2 cox2 PROPN ct-9466 22 134 ) ) PUNCT ct-9466 22 135 and and CCONJ ct-9466 22 136 prostaglandin prostaglandin NOUN ct-9466 22 137 f f NOUN ct-9466 22 138 synthase synthase NOUN ct-9466 22 139 ( ( PUNCT ct-9466 22 140 pgfs pgfs NOUN ct-9466 22 141 ) ) PUNCT ct-9466 22 142 are be AUX ct-9466 22 143 significantly significantly ADV ct-9466 22 144 upregulated upregulate VERB ct-9466 22 145 ( ( PUNCT ct-9466 22 146 3.75 3.75 NUM ct-9466 22 147 and and CCONJ ct-9466 22 148 3.15 3.15 NUM ct-9466 22 149 times time NOUN ct-9466 22 150 in in ADP ct-9466 22 151 atrophic atrophic ADJ ct-9466 22 152 pyometra pyometra NOUN ct-9466 22 153 compared compare VERB ct-9466 22 154 to to ADP ct-9466 22 155 hyperplastic hyperplastic ADJ ct-9466 22 156 pyometra pyometra NOUN ct-9466 22 157 , , PUNCT ct-9466 22 158 respectively).19 respectively).19 PROPN ct-9466 22 159 this this DET ct-9466 22 160 results result VERB ct-9466 22 161 in in ADP ct-9466 22 162 greater great ADJ ct-9466 22 163 expression expression NOUN ct-9466 22 164 of of ADP ct-9466 22 165 proliferative proliferative ADJ ct-9466 22 166 ki-67 ki-67 ADJ ct-9466 22 167 marker marker NOUN ct-9466 22 168 in in ADP ct-9466 22 169 endometrial endometrial ADJ ct-9466 22 170 stromal stromal ADJ ct-9466 22 171 cells cell NOUN ct-9466 22 172 in in ADP ct-9466 22 173 response response NOUN ct-9466 22 174 to to ADP ct-9466 22 175 the the DET ct-9466 22 176 bacterial bacterial ADJ ct-9466 22 177 agent.13 agent.13 NOUN ct-9466 22 178 during during ADP ct-9466 22 179 inflammation inflammation NOUN ct-9466 22 180 , , PUNCT ct-9466 22 181 cox2 cox2 PROPN ct-9466 22 182 is be AUX ct-9466 22 183 an an DET ct-9466 22 184 important important ADJ ct-9466 22 185 source source NOUN ct-9466 22 186 of of ADP ct-9466 22 187 prostaglandins prostaglandin NOUN ct-9466 22 188 and and CCONJ ct-9466 22 189 thromboxane thromboxane NOUN ct-9466 22 190 a2 a2 PROPN ct-9466 22 191 . . PUNCT ct-9466 23 1 cox-2 cox-2 NOUN ct-9466 23 2 interacts interact VERB ct-9466 23 3 directly directly ADV ct-9466 23 4 with with ADP ct-9466 23 5 chemokines chemokine NOUN ct-9466 23 6 that that PRON ct-9466 23 7 are be AUX ct-9466 23 8 overexpressed overexpresse VERB ct-9466 23 9 in in ADP ct-9466 23 10 pyometra pyometra NOUN ct-9466 23 11 ( ( PUNCT ct-9466 23 12 e.g. e.g. ADV ct-9466 23 13 cxcl8 cxcl8 PROPN ct-9466 23 14 / / SYM ct-9466 23 15 il8 il8 PROPN ct-9466 23 16 , , PUNCT ct-9466 23 17 cxcl14).17 cxcl14).17 X ct-9466 23 18 overexpression overexpression NOUN ct-9466 23 19 of of ADP ct-9466 23 20 cxcl14 cxcl14 NOUN ct-9466 23 21 contributes contribute VERB ct-9466 23 22 to to ADP ct-9466 23 23 inflammatory inflammatory ADJ ct-9466 23 24 cell cell NOUN ct-9466 23 25 infiltration infiltration NOUN ct-9466 23 26 into into ADP ct-9466 23 27 uterine uterine ADJ ct-9466 23 28 lumen luman NOUN ct-9466 23 29 , , PUNCT ct-9466 23 30 due due ADP ct-9466 23 31 to to ADP ct-9466 23 32 its its PRON ct-9466 23 33 chemoattractant chemoattractant ADJ ct-9466 23 34 action action NOUN ct-9466 23 35 in in ADP ct-9466 23 36 monocytes monocyte NOUN ct-9466 23 37 and and CCONJ ct-9466 23 38 natural natural ADJ ct-9466 23 39 killer killer NOUN ct-9466 23 40 cells.20 cells.20 PROPN ct-9466 23 41 however however ADV ct-9466 23 42 , , PUNCT ct-9466 23 43 cxcl10 cxcl10 NOUN ct-9466 23 44 has have VERB ct-9466 23 45 antimicrobial antimicrobial ADJ ct-9466 23 46 activity activity NOUN ct-9466 23 47 against against ADP ct-9466 23 48 e. e. PROPN ct-9466 23 49 coli.21 coli.21 PROPN ct-9466 23 50 in in ADP ct-9466 23 51 stromal stromal ADJ ct-9466 23 52 cells cell NOUN ct-9466 23 53 , , PUNCT ct-9466 23 54 cxcl10 cxcl10 NOUN ct-9466 23 55 may may AUX ct-9466 23 56 be be AUX ct-9466 23 57 involved involve VERB ct-9466 23 58 in in ADP ct-9466 23 59 recruitment recruitment NOUN ct-9466 23 60 and and CCONJ ct-9466 23 61 potentiation potentiation NOUN ct-9466 23 62 of of ADP ct-9466 23 63 t t PROPN ct-9466 23 64 helper helper NOUN ct-9466 23 65 1 1 NUM ct-9466 23 66 response.22 response.22 NOUN ct-9466 23 67 because because SCONJ ct-9466 23 68 il8 il8 PROPN ct-9466 23 69 and and CCONJ ct-9466 23 70 cxcl14 cxcl14 NOUN ct-9466 23 71 are be AUX ct-9466 23 72 induced induce VERB ct-9466 23 73 by by ADP ct-9466 23 74 cox2 cox2 NOUN ct-9466 23 75 , , PUNCT ct-9466 23 76 selective selective ADJ ct-9466 23 77 cox2 cox2 NOUN ct-9466 23 78 inhibitors inhibitor NOUN ct-9466 23 79 may may AUX ct-9466 23 80 mitigate mitigate VERB ct-9466 23 81 inflammatory inflammatory ADJ ct-9466 23 82 response response NOUN ct-9466 23 83 during during ADP ct-9466 23 84 pyometra.17 pyometra.17 ADJ ct-9466 23 85 cox2 cox2 NOUN ct-9466 23 86 is be AUX ct-9466 23 87 also also ADV ct-9466 23 88 downstream downstream ADJ ct-9466 23 89 of of ADP ct-9466 23 90 toll toll NOUN ct-9466 23 91 - - PUNCT ct-9466 23 92 like like ADJ ct-9466 23 93 receptor receptor NOUN ct-9466 23 94 ( ( PUNCT ct-9466 23 95 tlr tlr PROPN ct-9466 23 96 ) ) PUNCT ct-9466 23 97 signalling signal VERB ct-9466 23 98 after after ADP ct-9466 23 99 activation activation NOUN ct-9466 23 100 by by ADP ct-9466 23 101 endogenous endogenous ADJ ct-9466 23 102 s100 s100 PROPN ct-9466 23 103 proteins protein NOUN ct-9466 23 104 and and CCONJ ct-9466 23 105 other other ADJ ct-9466 23 106 stimuli stimulus NOUN ct-9466 23 107 ( ( PUNCT ct-9466 23 108 e.g. e.g. ADV ct-9466 23 109 lps lps PROPN ct-9466 23 110 ) ) PUNCT ct-9466 23 111 . . PUNCT ct-9466 24 1 conserved conserve VERB ct-9466 24 2 pathogen pathogen NOUN ct-9466 24 3 - - PUNCT ct-9466 24 4 associated associate VERB ct-9466 24 5 molecular molecular ADJ ct-9466 24 6 patterns pattern NOUN ct-9466 24 7 synthesized synthesize VERB ct-9466 24 8 by by ADP ct-9466 24 9 microorganisms microorganism NOUN ct-9466 24 10 ( ( PUNCT ct-9466 24 11 lps lps PROPN ct-9466 24 12 ) ) PUNCT ct-9466 24 13 are be AUX ct-9466 24 14 recognized recognize VERB ct-9466 24 15 by by ADP ct-9466 24 16 tlr tlr PROPN ct-9466 24 17 to to PART ct-9466 24 18 initiate initiate VERB ct-9466 24 19 an an DET ct-9466 24 20 innate innate ADJ ct-9466 24 21 immune immune ADJ ct-9466 24 22 response response NOUN ct-9466 24 23 . . PUNCT ct-9466 25 1 normal normal ADJ ct-9466 25 2 canine canine NOUN ct-9466 25 3 endometrial endometrial ADJ ct-9466 25 4 epithelial epithelial ADJ ct-9466 25 5 and and CCONJ ct-9466 25 6 stromal stromal ADJ ct-9466 25 7 cells cell NOUN ct-9466 25 8 express express VERB ct-9466 25 9 tlr4 tlr4 NOUN ct-9466 25 10 , , PUNCT ct-9466 25 11 but but CCONJ ct-9466 25 12 both both DET ct-9466 25 13 tlr2 tlr2 VERB ct-9466 25 14 and and CCONJ ct-9466 25 15 tlr4 tlr4 NOUN ct-9466 25 16 are be AUX ct-9466 25 17 upregulated upregulate VERB ct-9466 25 18 in in ADP ct-9466 25 19 pyometra pyometra NOUN ct-9466 25 20 . . PUNCT ct-9466 26 1 tlr tlr PROPN ct-9466 26 2 mediated mediate VERB ct-9466 26 3 immune immune ADJ ct-9466 26 4 surveillance surveillance NOUN ct-9466 26 5 is be AUX ct-9466 26 6 an an DET ct-9466 26 7 important important ADJ ct-9466 26 8 component component NOUN ct-9466 26 9 in in ADP ct-9466 26 10 uterine uterine ADJ ct-9466 26 11 defence defence NOUN ct-9466 26 12 mechanisms.23 mechanisms.23 PROPN ct-9466 26 13 continuous continuous ADJ ct-9466 26 14 activation activation NOUN ct-9466 26 15 of of ADP ct-9466 26 16 tlr tlr PROPN ct-9466 26 17 by by ADP ct-9466 26 18 both both CCONJ ct-9466 26 19 endogenous endogenous ADJ ct-9466 26 20 and and CCONJ ct-9466 26 21 exogenous exogenous ADJ ct-9466 26 22 stimulus stimulus NOUN ct-9466 26 23 can can AUX ct-9466 26 24 lead lead VERB ct-9466 26 25 to to ADP ct-9466 26 26 an an DET ct-9466 26 27 exacerbated exacerbate VERB ct-9466 26 28 inflammatory inflammatory ADJ ct-9466 26 29 response response NOUN ct-9466 26 30 in in ADP ct-9466 26 31 pyometra pyometra NOUN ct-9466 26 32 . . PUNCT ct-9466 27 1 lps lps PROPN ct-9466 27 2 interacts interact VERB ct-9466 27 3 with with ADP ct-9466 27 4 lactoferrin lactoferrin NOUN ct-9466 27 5 ( ( PUNCT ct-9466 27 6 ltf ltf PROPN ct-9466 27 7 ) ) PUNCT ct-9466 27 8 on on ADP ct-9466 27 9 the the DET ct-9466 27 10 surface surface NOUN ct-9466 27 11 of of ADP ct-9466 27 12 bacteria bacteria NOUN ct-9466 27 13 to to PART ct-9466 27 14 activate activate VERB ct-9466 27 15 tlr4 tlr4 NOUN ct-9466 27 16 on on ADP ct-9466 27 17 surfaces surface NOUN ct-9466 27 18 of of ADP ct-9466 27 19 phagocytes phagocyte NOUN ct-9466 27 20 and and CCONJ ct-9466 27 21 epithelial epithelial ADJ ct-9466 27 22 cells.17 cells.17 NOUN ct-9466 27 23 both both CCONJ ct-9466 27 24 ltf ltf PROPN ct-9466 27 25 gene gene NOUN ct-9466 27 26 and and CCONJ ct-9466 27 27 protein protein NOUN ct-9466 27 28 are be AUX ct-9466 27 29 overexpressed overexpresse VERB ct-9466 27 30 in in ADP ct-9466 27 31 pyometra.24 pyometra.24 NOUN ct-9466 27 32 calcium calcium NOUN ct-9466 27 33 - - PUNCT ct-9466 27 34 binding bind VERB ct-9466 27 35 proteins protein NOUN ct-9466 27 36 of of ADP ct-9466 27 37 the the DET ct-9466 27 38 s100 s100 PROPN ct-9466 27 39 family family NOUN ct-9466 27 40 ( ( PUNCT ct-9466 27 41 e.g. e.g. ADV ct-9466 27 42 s100a8 s100a8 PROPN ct-9466 27 43 , , PUNCT ct-9466 27 44 s100a9 s100a9 PROPN ct-9466 27 45 , , PUNCT ct-9466 27 46 s100a12 s100a12 NUM ct-9466 27 47 ) ) PUNCT ct-9466 27 48 have have AUX ct-9466 27 49 been be AUX ct-9466 27 50 identified identify VERB ct-9466 27 51 as as ADP ct-9466 27 52 endogenous endogenous ADJ ct-9466 27 53 danger danger NOUN ct-9466 27 54 - - PUNCT ct-9466 27 55 associated associate VERB ct-9466 27 56 molecular molecular ADJ ct-9466 27 57 patterns pattern NOUN ct-9466 27 58 ( ( PUNCT ct-9466 27 59 damps).17 damps).17 NOUN ct-9466 27 60 damps damp NOUN ct-9466 27 61 are be AUX ct-9466 27 62 intracellular intracellular ADJ ct-9466 27 63 640clinical 640clinical PROPN ct-9466 27 64 theriogenology theriogenology NOUN ct-9466 27 65 • • NOUN ct-9466 27 66 volume volume NOUN ct-9466 27 67 11 11 NUM ct-9466 27 68 , , PUNCT ct-9466 27 69 number number NOUN ct-9466 27 70 4 4 NUM ct-9466 27 71 • • NOUN ct-9466 27 72 december december PROPN ct-9466 27 73 2019 2019 NUM ct-9466 27 74     SPACE ct-9466 27 75 molecules molecule NOUN ct-9466 27 76 released release VERB ct-9466 27 77 following follow VERB ct-9466 27 78 cell cell NOUN ct-9466 27 79 death death NOUN ct-9466 27 80 and and CCONJ ct-9466 27 81 are be AUX ct-9466 27 82 recognized recognize VERB ct-9466 27 83 by by ADP ct-9466 27 84 the the DET ct-9466 27 85 innate innate ADJ ct-9466 27 86 immune immune ADJ ct-9466 27 87 system system NOUN ct-9466 27 88 . . PUNCT ct-9466 28 1 s100a8 s100a8 PROPN ct-9466 28 2 and and CCONJ ct-9466 28 3 s100a9 s100a9 PROPN ct-9466 28 4 stimulate stimulate VERB ct-9466 28 5 production production NOUN ct-9466 28 6 of of ADP ct-9466 28 7 several several ADJ ct-9466 28 8 pro pro ADJ ct-9466 28 9 - - ADJ ct-9466 28 10 inflammatory inflammatory ADJ ct-9466 28 11 cytokines cytokine NOUN ct-9466 28 12 ( ( PUNCT ct-9466 28 13 e.g. e.g. ADV ct-9466 28 14 tumor tumor NOUN ct-9466 28 15 necrosis necrosis NOUN ct-9466 28 16 factor factor NOUN ct-9466 28 17 ( ( PUNCT ct-9466 28 18 tnf tnf PROPN ct-9466 28 19 ) ) PUNCT ct-9466 28 20 , , PUNCT ct-9466 28 21 il6 il6 NOUN ct-9466 28 22 , , PUNCT ct-9466 28 23 il1b il1b PROPN ct-9466 28 24 , , PUNCT ct-9466 28 25 il8).17 il8).17 VERB ct-9466 28 26 another another DET ct-9466 28 27 op op NOUN ct-9466 28 28 upregulated upregulate VERB ct-9466 28 29 gene gene NOUN ct-9466 28 30 in in ADP ct-9466 28 31 pyometra pyometra NOUN ct-9466 28 32 is be AUX ct-9466 28 33 secretory secretory ADJ ct-9466 28 34 leukocyte leukocyte NOUN ct-9466 28 35 peptidase peptidase NOUN ct-9466 28 36 inhibitor inhibitor NOUN ct-9466 28 37 ( ( PUNCT ct-9466 28 38 slpi slpi NOUN ct-9466 28 39 ) ) PUNCT ct-9466 28 40 gene.17 gene.17 NOUN ct-9466 28 41 slpi slpi NOUN ct-9466 28 42 encodes encode NOUN ct-9466 28 43 for for ADP ct-9466 28 44 an an DET ct-9466 28 45 antimicrobial antimicrobial ADJ ct-9466 28 46 peptide peptide NOUN ct-9466 28 47 secreted secrete VERB ct-9466 28 48 by by ADP ct-9466 28 49 epithelial epithelial ADJ ct-9466 28 50 tissues tissue NOUN ct-9466 28 51 . . PUNCT ct-9466 29 1 spli spli NOUN ct-9466 29 2 modulates modulate VERB ct-9466 29 3 infection infection NOUN ct-9466 29 4 and and CCONJ ct-9466 29 5 inflammation inflammation NOUN ct-9466 29 6 by by ADP ct-9466 29 7 neutralizing neutralize VERB ct-9466 29 8 lps lps PROPN ct-9466 29 9 and and CCONJ ct-9466 29 10 reducing reduce VERB ct-9466 29 11 activation activation NOUN ct-9466 29 12 of of ADP ct-9466 29 13 tlrs.17 tlrs.17 ADJ ct-9466 29 14 bacteria bacteria NOUN ct-9466 29 15 positive positive ADJ ct-9466 29 16 uterine uterine ADJ ct-9466 29 17 cultures culture NOUN ct-9466 29 18 have have AUX ct-9466 29 19 been be AUX ct-9466 29 20 obtained obtain VERB ct-9466 29 21 during during ADP ct-9466 29 22 various various ADJ ct-9466 29 23 stages stage NOUN ct-9466 29 24 of of ADP ct-9466 29 25 the the DET ct-9466 29 26 reproductive reproductive ADJ ct-9466 29 27 cycle cycle NOUN ct-9466 29 28 in in ADP ct-9466 29 29 bitches bitch NOUN ct-9466 29 30 without without ADP ct-9466 29 31 reproductive reproductive ADJ ct-9466 29 32 problems.25 problems.25 NOUN ct-9466 29 33 common common ADJ ct-9466 29 34 bacteria bacteria NOUN ct-9466 29 35 in in ADP ct-9466 29 36 uteruses uterus NOUN ct-9466 29 37 of of ADP ct-9466 29 38 healthy healthy ADJ ct-9466 29 39 bitches bitch NOUN ct-9466 29 40 reflect reflect VERB ct-9466 29 41 bacterial bacterial ADJ ct-9466 29 42 flora flora NOUN ct-9466 29 43 of of ADP ct-9466 29 44 vagina vagina ADJ ct-9466 29 45 and and CCONJ ct-9466 29 46 cervix.25 cervix.25 ADJ ct-9466 29 47 presence presence NOUN ct-9466 29 48 of of ADP ct-9466 29 49 mixed mixed ADJ ct-9466 29 50 bacteria bacteria NOUN ct-9466 29 51 in in ADP ct-9466 29 52 uterus uterus NOUN ct-9466 29 53 during during ADP ct-9466 29 54 proestrus proestrus NOUN ct-9466 29 55 and and CCONJ ct-9466 29 56 estrus estrus NOUN ct-9466 29 57 is be AUX ct-9466 29 58 not not PART ct-9466 29 59 uncommon uncommon ADJ ct-9466 29 60 in in ADP ct-9466 29 61 dogs dog NOUN ct-9466 29 62 , , PUNCT ct-9466 29 63 presumably presumably ADV ct-9466 29 64 due due ADJ ct-9466 29 65 to to ADP ct-9466 29 66 cervical cervical ADJ ct-9466 29 67 dilation.25 dilation.25 NOUN ct-9466 29 68 presence presence NOUN ct-9466 29 69 of of ADP ct-9466 29 70 intrauterine intrauterine ADJ ct-9466 29 71 bacteria bacteria NOUN ct-9466 29 72 cultured cultured ADJ ct-9466 29 73 from from ADP ct-9466 29 74 uterine uterine ADJ ct-9466 29 75 lumen luman NOUN ct-9466 29 76 following follow VERB ct-9466 29 77 elective elective ADJ ct-9466 29 78 ovariohysterectomies ovariohysterectomie NOUN ct-9466 29 79 during during ADP ct-9466 29 80 diestrus diestrus NOUN ct-9466 29 81 is be AUX ct-9466 29 82 counterintuitive counterintuitive ADJ ct-9466 29 83 . . PUNCT ct-9466 30 1 in in ADP ct-9466 30 2 1 1 NUM ct-9466 30 3 study study NOUN ct-9466 30 4 , , PUNCT ct-9466 30 5 > > X ct-9466 30 6 10 10 NUM ct-9466 30 7 % % NOUN ct-9466 30 8 of of ADP ct-9466 30 9 “ " PUNCT ct-9466 30 10 normal normal ADJ ct-9466 30 11 ” " PUNCT ct-9466 30 12 diestrous diestrous ADJ ct-9466 30 13 uteruses uterus NOUN ct-9466 30 14 yielded yield VERB ct-9466 30 15 positive positive ADJ ct-9466 30 16 bacterial bacterial ADJ ct-9466 30 17 cultures.25 cultures.25 NOUN ct-9466 30 18 organisms organism NOUN ct-9466 30 19 isolated isolate VERB ct-9466 30 20 included include VERB ct-9466 30 21 enterococcus enterococcus NOUN ct-9466 30 22 sp sp NOUN ct-9466 30 23 . . PROPN ct-9466 30 24 , , PUNCT ct-9466 30 25 bacillus bacillus NOUN ct-9466 30 26 sp sp NOUN ct-9466 30 27 . . PROPN ct-9466 30 28 , , PUNCT ct-9466 30 29 and and CCONJ ct-9466 30 30 undefined undefined ADJ ct-9466 30 31 gram gram PROPN ct-9466 30 32 positive positive ADJ ct-9466 30 33 species.25 species.25 PROPN ct-9466 30 34 furthermore furthermore ADV ct-9466 30 35 , , PUNCT ct-9466 30 36 ~ ~ PUNCT ct-9466 30 37 16 16 NUM ct-9466 30 38 % % NOUN ct-9466 30 39 of of ADP ct-9466 30 40 bitches bitch NOUN ct-9466 30 41 believed believe VERB ct-9466 30 42 to to PART ct-9466 30 43 have have VERB ct-9466 30 44 pyometra pyometra NOUN ct-9466 30 45 have have VERB ct-9466 30 46 negative negative ADJ ct-9466 30 47 bacteriologic bacteriologic ADJ ct-9466 30 48 findings finding NOUN ct-9466 30 49 following follow VERB ct-9466 30 50 ovariohysterectomy.25 ovariohysterectomy.25 NOUN ct-9466 30 51 however however ADV ct-9466 30 52 , , PUNCT ct-9466 30 53 there there PRON ct-9466 30 54 were be VERB ct-9466 30 55 no no DET ct-9466 30 56 attempts attempt NOUN ct-9466 30 57 to to PART ct-9466 30 58 detect detect VERB ct-9466 30 59 anaerobic anaerobic ADJ ct-9466 30 60 organisms organism NOUN ct-9466 30 61 or or CCONJ ct-9466 30 62 isolate isolate VERB ct-9466 30 63 other other ADJ ct-9466 30 64 bacteria bacteria NOUN ct-9466 30 65 such such ADJ ct-9466 30 66 as as ADP ct-9466 30 67 mycoplasma mycoplasma NOUN ct-9466 30 68 sp sp PROPN ct-9466 30 69 . . PROPN ct-9466 30 70 , , PUNCT ct-9466 30 71 leptospira leptospira PROPN ct-9466 30 72 sp sp PROPN ct-9466 30 73 . . PROPN ct-9466 30 74 , , PUNCT ct-9466 30 75 or or CCONJ ct-9466 30 76 chlamydia chlamydia NOUN ct-9466 30 77 sp.25 sp.25 NOUN ct-9466 30 78 with with ADP ct-9466 30 79 respect respect NOUN ct-9466 30 80 to to ADP ct-9466 30 81 pyometra pyometra NOUN ct-9466 30 82 , , PUNCT ct-9466 30 83 e. e. PROPN ct-9466 30 84 coli coli PROPN ct-9466 30 85 is be AUX ct-9466 30 86 the the DET ct-9466 30 87 most most ADV ct-9466 30 88 common common ADJ ct-9466 30 89 organism organism NOUN ct-9466 30 90 isolated isolate VERB ct-9466 30 91 in in ADP ct-9466 30 92 90 90 NUM ct-9466 30 93 % % NOUN ct-9466 30 94 of of ADP ct-9466 30 95 cases case NOUN ct-9466 30 96 with with ADP ct-9466 30 97 positive positive ADJ ct-9466 30 98 culture.26 culture.26 NOUN ct-9466 30 99 - - PUNCT ct-9466 30 100 27 27 NUM ct-9466 30 101 however however ADV ct-9466 30 102 , , PUNCT ct-9466 30 103 other other ADJ ct-9466 30 104 bacteria bacteria NOUN ct-9466 30 105 are be AUX ct-9466 30 106 also also ADV ct-9466 30 107 cultured cultured ADJ ct-9466 30 108 ( ( PUNCT ct-9466 30 109 table table NOUN ct-9466 30 110 1 1 NUM ct-9466 30 111 ) ) PUNCT ct-9466 30 112 , , PUNCT ct-9466 30 113 with with ADP ct-9466 30 114 enterococcus enterococcus NOUN ct-9466 30 115 avium avium NOUN ct-9466 30 116 isolated isolate VERB ct-9466 30 117 from from ADP ct-9466 30 118 the the DET ct-9466 30 119 uterus uterus NOUN ct-9466 30 120 of of ADP ct-9466 30 121 a a DET ct-9466 30 122 dog dog NOUN ct-9466 30 123 with with ADP ct-9466 30 124 an an DET ct-9466 30 125 emphysematous emphysematous ADJ ct-9466 30 126 pyometra pyometra NOUN ct-9466 30 127 . . PUNCT ct-9466 31 1 in in ADP ct-9466 31 2 > > X ct-9466 31 3 90 90 NUM ct-9466 31 4 % % NOUN ct-9466 31 5 of of ADP ct-9466 31 6 cases case NOUN ct-9466 31 7 of of ADP ct-9466 31 8 canine canine NOUN ct-9466 31 9 pyometra pyometra NOUN ct-9466 31 10 , , PUNCT ct-9466 31 11 only only ADV ct-9466 31 12 a a DET ct-9466 31 13 single single ADJ ct-9466 31 14 bacterial bacterial ADJ ct-9466 31 15 species specie NOUN ct-9466 31 16 was be AUX ct-9466 31 17 cultured.25 cultured.25 NOUN ct-9466 31 18 it it PRON ct-9466 31 19 is be AUX ct-9466 31 20 important important ADJ ct-9466 31 21 to to PART ct-9466 31 22 mention mention VERB ct-9466 31 23 that that SCONJ ct-9466 31 24 when when SCONJ ct-9466 31 25 > > X ct-9466 31 26 1 1 NUM ct-9466 31 27 bacterial bacterial ADJ ct-9466 31 28 species specie NOUN ct-9466 31 29 is be AUX ct-9466 31 30 isolated isolate VERB ct-9466 31 31 from from ADP ct-9466 31 32 canine canine NOUN ct-9466 31 33 pyometra pyometra NOUN ct-9466 31 34 , , PUNCT ct-9466 31 35 e. e. PROPN ct-9466 31 36 coli coli PROPN ct-9466 31 37 is be AUX ct-9466 31 38 always always ADV ct-9466 31 39 isolated.25 isolated.25 ADJ ct-9466 31 40 escherichia escherichia NOUN ct-9466 31 41 coli coli NOUN ct-9466 31 42 strains strain NOUN ct-9466 31 43 of of ADP ct-9466 31 44 these these PRON ct-9466 31 45 that that PRON ct-9466 31 46 are be AUX ct-9466 31 47 isolated isolate VERB ct-9466 31 48 from from ADP ct-9466 31 49 pyometra pyometra NOUN ct-9466 31 50 are be AUX ct-9466 31 51 those those PRON ct-9466 31 52 that that PRON ct-9466 31 53 normally normally ADV ct-9466 31 54 inhabit inhabit VERB ct-9466 31 55 canine canine NOUN ct-9466 31 56 intestine intestine NOUN ct-9466 31 57 and and CCONJ ct-9466 31 58 those those PRON ct-9466 31 59 present present ADJ ct-9466 31 60 in in ADP ct-9466 31 61 urinary urinary ADJ ct-9466 31 62 tract tract NOUN ct-9466 31 63 infections.28 infections.28 NOUN ct-9466 31 64 escherichia escherichia NOUN ct-9466 31 65 coli coli NOUN ct-9466 31 66 isolated isolate VERB ct-9466 31 67 from from ADP ct-9466 31 68 canine canine NOUN ct-9466 31 69 pyometra pyometra NOUN ct-9466 31 70 is be AUX ct-9466 31 71 mainly mainly ADV ct-9466 31 72 assigned assign VERB ct-9466 31 73 to to ADP ct-9466 31 74 phylogenetic phylogenetic ADJ ct-9466 31 75 group group NOUN ct-9466 31 76 b2 b2 NOUN ct-9466 31 77 and and CCONJ ct-9466 31 78 characterized characterize VERB ct-9466 31 79 by by ADP ct-9466 31 80 a a DET ct-9466 31 81 high high ADJ ct-9466 31 82 number number NOUN ct-9466 31 83 of of ADP ct-9466 31 84 table table NOUN ct-9466 31 85 1 1 NUM ct-9466 31 86 . . PUNCT ct-9466 31 87 bacteria bacteria NOUN ct-9466 31 88 other other ADJ ct-9466 31 89 than than ADP ct-9466 31 90 escherichia escherichia NOUN ct-9466 31 91 coli coli NOUN ct-9466 31 92 cultured cultured ADJ ct-9466 31 93 from from ADP ct-9466 31 94 cases case NOUN ct-9466 31 95 of of ADP ct-9466 31 96 canine canine NOUN ct-9466 31 97 pyometra.25,72 pyometra.25,72 ADJ ct-9466 31 98 bacteria bacteria NOUN ct-9466 31 99 frequency frequency NOUN ct-9466 31 100 ( ( PUNCT ct-9466 31 101 % % NOUN ct-9466 31 102 ) ) PUNCT ct-9466 31 103 β β NOUN ct-9466 31 104 - - ADJ ct-9466 31 105 hemolytic hemolytic ADJ ct-9466 31 106 streptococcus streptococcus VERB ct-9466 31 107 15 15 NUM ct-9466 31 108 citrobacter citrobacter NOUN ct-9466 31 109 spp spp NOUN ct-9466 31 110 . . PUNCT ct-9466 32 1 10 10 NUM ct-9466 32 2 unidentified unidentified ADJ ct-9466 32 3 enterobacteriaceae enterobacteriaceae PROPN ct-9466 32 4 5.9 5.9 NUM ct-9466 32 5 33.3 33.3 NUM ct-9466 32 6 streptococcus streptococcus NOUN ct-9466 32 7 spp spp NOUN ct-9466 32 8 . . PUNCT ct-9466 33 1 5.1 5.1 NUM ct-9466 33 2 klebsiella klebsiella PROPN ct-9466 33 3 spp spp NOUN ct-9466 33 4 . . PROPN ct-9466 33 5 4.2 4.2 NUM ct-9466 33 6 enterococcus enterococcus NOUN ct-9466 33 7 spp spp NOUN ct-9466 33 8 . . PROPN ct-9466 33 9 3.4 3.4 NUM ct-9466 33 10 actinomycetaceae actinomycetaceae PROPN ct-9466 33 11 spp spp NOUN ct-9466 33 12 . . PUNCT ct-9466 33 13 2.5 2.5 NUM ct-9466 33 14 staphylococcus staphylococcus NOUN ct-9466 33 15 spp spp NOUN ct-9466 33 16 . . PUNCT ct-9466 34 1 2.5 2.5 NUM ct-9466 34 2 16.7 16.7 NUM ct-9466 34 3 pseudomonas pseudomona NOUN ct-9466 34 4 spp spp NOUN ct-9466 34 5 . . PUNCT ct-9466 34 6 1.7 1.7 NUM ct-9466 34 7 2.0 2.0 NUM ct-9466 34 8 undefined undefined ADJ ct-9466 34 9 gram gram NOUN ct-9466 34 10 negatives negative NOUN ct-9466 34 11 0.8 0.8 NUM ct-9466 34 12 undefined undefined ADJ ct-9466 34 13 gram gram NOUN ct-9466 34 14 positives positive NOUN ct-9466 34 15 0.8 0.8 NUM ct-9466 34 16 proteus proteus NOUN ct-9466 34 17 0.8 0.8 NUM ct-9466 34 18 16.7 16.7 NUM ct-9466 34 19 uropathogenic uropathogenic ADJ ct-9466 34 20 e. e. PROPN ct-9466 34 21 coli coli PROPN ct-9466 34 22 ( ( PUNCT ct-9466 34 23 upec upec NOUN ct-9466 34 24 ) ) PUNCT ct-9466 34 25 virulence virulence NOUN ct-9466 34 26 factor factor NOUN ct-9466 34 27 ( ( PUNCT ct-9466 34 28 vf vf NOUN ct-9466 34 29 ) ) PUNCT ct-9466 34 30 genes gene NOUN ct-9466 34 31 and and CCONJ ct-9466 34 32 pathogenicity pathogenicity NOUN ct-9466 34 33 - - PUNCT ct-9466 34 34 associated associate VERB ct-9466 34 35 island island NOUN ct-9466 34 36 markers.28 markers.28 NOUN ct-9466 34 37 escherichia escherichia NOUN ct-9466 34 38 coli coli NOUN ct-9466 34 39 have have VERB ct-9466 34 40 vf vf NOUN ct-9466 34 41 genes gene NOUN ct-9466 34 42 encoding encode VERB ct-9466 34 43 for for ADP ct-9466 34 44 adhesins adhesin NOUN ct-9466 34 45 ( ( PUNCT ct-9466 34 46 including include VERB ct-9466 34 47 fimh fimh NOUN ct-9466 34 48 , , PUNCT ct-9466 34 49 papc papc NOUN ct-9466 34 50 and and CCONJ ct-9466 34 51 papgiii papgiii NOUN ct-9466 34 52 ) ) PUNCT ct-9466 34 53 , , PUNCT ct-9466 34 54 toxins toxin NOUN ct-9466 34 55 ( ( PUNCT ct-9466 34 56 including include VERB ct-9466 34 57 hlya hlya PROPN ct-9466 34 58 / / SYM ct-9466 34 59 f f PROPN ct-9466 34 60 , , PUNCT ct-9466 34 61 usp usp NOUN ct-9466 34 62 and and CCONJ ct-9466 34 63 asta asta PROPN ct-9466 34 64 ) ) PUNCT ct-9466 34 65 , , PUNCT ct-9466 34 66 and and CCONJ ct-9466 34 67 other other ADJ ct-9466 34 68 factors factor NOUN ct-9466 34 69 ( ( PUNCT ct-9466 34 70 e.g. e.g. ADV ct-9466 34 71 those those PRON ct-9466 34 72 involved involve VERB ct-9466 34 73 in in ADP ct-9466 34 74 escape escape NOUN ct-9466 34 75 from from ADP ct-9466 34 76 host host NOUN ct-9466 34 77 defences defence NOUN ct-9466 34 78 and and CCONJ ct-9466 34 79 iron iron NOUN ct-9466 34 80 uptake).28 uptake).28 PROPN ct-9466 34 81 frequency frequency NOUN ct-9466 34 82 of of ADP ct-9466 34 83 vf vf NOUN ct-9466 34 84 genes gene NOUN ct-9466 34 85 in in ADP ct-9466 34 86 e. e. PROPN ct-9466 34 87 coli coli PROPN ct-9466 34 88 isolates isolate NOUN ct-9466 34 89 from from ADP ct-9466 34 90 canine canine NOUN ct-9466 34 91 pyometra pyometra NOUN ct-9466 34 92 are be AUX ct-9466 34 93 summarized summarize VERB ct-9466 34 94 in in ADP ct-9466 34 95 table table NOUN ct-9466 34 96 2 2 NUM ct-9466 34 97 . . NOUN ct-9466 34 98 escherichia escherichia NOUN ct-9466 34 99 coli coli NOUN ct-9466 34 100 isolates isolate NOUN ct-9466 34 101 with with ADP ct-9466 34 102 > > SYM ct-9466 34 103 2 2 NUM ct-9466 34 104 adhesin adhesin NOUN ct-9466 34 105 genes gene NOUN ct-9466 34 106 imply imply VERB ct-9466 34 107 that that SCONJ ct-9466 34 108 a a DET ct-9466 34 109 combination combination NOUN ct-9466 34 110 of of ADP ct-9466 34 111 genes gene NOUN ct-9466 34 112 confers confer VERB ct-9466 34 113 an an DET ct-9466 34 114 641 641 NUM ct-9466 34 115 clinical clinical ADJ ct-9466 34 116 theriogenology theriogenology NOUN ct-9466 34 117 • • NOUN ct-9466 34 118 volume volume NOUN ct-9466 34 119 11 11 NUM ct-9466 34 120 , , PUNCT ct-9466 34 121 number number NOUN ct-9466 34 122 4 4 NUM ct-9466 34 123 • • NOUN ct-9466 34 124 december december PROPN ct-9466 34 125 2019 2019 NUM ct-9466 34 126     SPACE ct-9466 34 127 advantage.28 advantage.28 NOUN ct-9466 34 128 strongly strongly ADV ct-9466 34 129 virulent virulent ADJ ct-9466 34 130 strains strain NOUN ct-9466 34 131 of of ADP ct-9466 34 132 e. e. PROPN ct-9466 34 133 coli coli PROPN ct-9466 34 134 ( ( PUNCT ct-9466 34 135 e.g. e.g. ADV ct-9466 34 136 nau nau PROPN ct-9466 34 137 - - PUNCT ct-9466 34 138 b b NOUN ct-9466 34 139 ) ) PUNCT ct-9466 34 140 contain contain VERB ct-9466 34 141 7 7 NUM ct-9466 34 142 virulence virulence NOUN ct-9466 34 143 genes gene NOUN ct-9466 34 144 . . PUNCT ct-9466 35 1 when when SCONJ ct-9466 35 2 strongly strongly ADV ct-9466 35 3 virulent virulent ADJ ct-9466 35 4 strains strain NOUN ct-9466 35 5 of of ADP ct-9466 35 6 e. e. PROPN ct-9466 35 7 coli coli NOUN ct-9466 35 8 are be AUX ct-9466 35 9 inoculated inoculate VERB ct-9466 35 10 into into ADP ct-9466 35 11 female female ADJ ct-9466 35 12 dogs dog NOUN ct-9466 35 13 , , PUNCT ct-9466 35 14 they they PRON ct-9466 35 15 produce produce VERB ct-9466 35 16 symptoms symptom NOUN ct-9466 35 17 of of ADP ct-9466 35 18 pyometra pyometra NOUN ct-9466 35 19 with with ADP ct-9466 35 20 an an DET ct-9466 35 21 earlier early ADJ ct-9466 35 22 onset onset NOUN ct-9466 35 23 and and CCONJ ct-9466 35 24 greater great ADJ ct-9466 35 25 severity severity NOUN ct-9466 35 26 than than ADP ct-9466 35 27 weakly weakly ADJ ct-9466 35 28 virulent virulent ADJ ct-9466 35 29 strains strain NOUN ct-9466 35 30 of of ADP ct-9466 35 31 e. e. PROPN ct-9466 35 32 coli coli PROPN ct-9466 35 33 ( ( PUNCT ct-9466 35 34 e.g. e.g. ADV ct-9466 35 35 nau nau PROPN ct-9466 35 36 - - PROPN ct-9466 35 37 i i PROPN ct-9466 35 38 ) ) PUNCT ct-9466 35 39 with with SCONJ ct-9466 35 40 fewer few ADJ ct-9466 35 41 virulence virulence NOUN ct-9466 35 42 genes.28 genes.28 NOUN ct-9466 35 43 alpha alpha NOUN ct-9466 35 44 - - PUNCT ct-9466 35 45 hemolysin hemolysin NOUN ct-9466 35 46 ( ( PUNCT ct-9466 35 47 hlya hlya ADJ ct-9466 35 48 ) ) PUNCT ct-9466 35 49 vf vf PROPN ct-9466 35 50 gene gene NOUN ct-9466 35 51 was be AUX ct-9466 35 52 detected detect VERB ct-9466 35 53 in in ADP ct-9466 35 54 35 35 NUM ct-9466 35 55 52 52 NUM ct-9466 35 56 % % NOUN ct-9466 35 57 of of ADP ct-9466 35 58 e. e. PROPN ct-9466 35 59 coli coli PROPN ct-9466 35 60 pyometra pyometra PROPN ct-9466 35 61 cases.27,29 cases.27,29 PROPN ct-9466 35 62 - - PUNCT ct-9466 35 63 30 30 NUM ct-9466 35 64 hlya hlya NOUN ct-9466 35 65 is be AUX ct-9466 35 66 an an DET ct-9466 35 67 rtx rtx NOUN ct-9466 35 68 pore pore NOUN ct-9466 35 69 - - PUNCT ct-9466 35 70 forming form VERB ct-9466 35 71 exotoxin exotoxin NOUN ct-9466 35 72 that that PRON ct-9466 35 73 contributes contribute VERB ct-9466 35 74 to to ADP ct-9466 35 75 virulence virulence NOUN ct-9466 35 76 of of ADP ct-9466 35 77 e. e. PROPN ct-9466 35 78 coli coli NOUN ct-9466 35 79 by by ADP ct-9466 35 80 inducing induce VERB ct-9466 35 81 tissue tissue NOUN ct-9466 35 82 damage damage NOUN ct-9466 35 83 and and CCONJ ct-9466 35 84 a a DET ct-9466 35 85 compromised compromise VERB ct-9466 35 86 early early ADJ ct-9466 35 87 uterine uterine ADJ ct-9466 35 88 immune immune ADJ ct-9466 35 89 response.27 response.27 PROPN ct-9466 35 90 table table NOUN ct-9466 35 91 2 2 NUM ct-9466 35 92 . . PUNCT ct-9466 35 93 virulence virulence NOUN ct-9466 35 94 genes gene NOUN ct-9466 35 95 frequency frequency NOUN ct-9466 35 96 in in ADP ct-9466 35 97 escherichia escherichia NOUN ct-9466 35 98 coli coli NOUN ct-9466 35 99 isolates isolate NOUN ct-9466 35 100 from from ADP ct-9466 35 101 canine canine PROPN ct-9466 35 102 pyometra.28,73 pyometra.28,73 PROPN ct-9466 35 103 gene gene NOUN ct-9466 35 104 encodes encode NOUN ct-9466 35 105 for for ADP ct-9466 35 106 frequency frequency NOUN ct-9466 35 107 expressed express VERB ct-9466 35 108 ( ( PUNCT ct-9466 35 109 % % INTJ ct-9466 35 110 ) ) PUNCT ct-9466 35 111 fimh fimh NOUN ct-9466 35 112 adhesin adhesin NOUN ct-9466 35 113 91.3 91.3 NUM ct-9466 35 114 irp-2 irp-2 NUM ct-9466 35 115 yersiniabactin yersiniabactin NOUN ct-9466 35 116 91.3 91.3 NUM ct-9466 35 117 fim fim NOUN ct-9466 35 118 type type NOUN ct-9466 35 119 1 1 NUM ct-9466 35 120 fimbriae fimbriae NOUN ct-9466 35 121 90.9 90.9 NUM ct-9466 35 122 fyua fyua NOUN ct-9466 35 123 yersiniabactin yersiniabactin VERB ct-9466 35 124 82.6 82.6 NUM ct-9466 35 125 hlya hlya ADJ ct-9466 35 126 hemolysin hemolysin NOUN ct-9466 35 127 30.4 30.4 NUM ct-9466 35 128 63.6 63.6 NUM ct-9466 35 129 sfa sfa NOUN ct-9466 35 130 s s PART ct-9466 35 131 fimbriae fimbria NOUN ct-9466 35 132 63.6 63.6 NUM ct-9466 35 133 pap pap NOUN ct-9466 36 1 p p NOUN ct-9466 36 2 fimbriae fimbriae NOUN ct-9466 36 3 63.6 63.6 NUM ct-9466 36 4 papc papc NOUN ct-9466 36 5 p p NOUN ct-9466 36 6 fimbriae fimbriae NOUN ct-9466 36 7 30.4 30.4 NUM ct-9466 36 8 63.6 63.6 NUM ct-9466 36 9 papgiii papgiii NOUN ct-9466 36 10 adhesin adhesin NOUN ct-9466 36 11 26.1 26.1 NUM ct-9466 36 12 63.6 63.6 NUM ct-9466 36 13 iron iron NOUN ct-9466 36 14 salmochelin salmochelin NOUN ct-9466 36 15 56.5 56.5 NUM ct-9466 36 16 usp usp NOUN ct-9466 36 17 uropathgenic uropathgenic ADJ ct-9466 36 18 - - PUNCT ct-9466 36 19 specific specific ADJ ct-9466 36 20 protein protein NOUN ct-9466 36 21 39.1 39.1 NUM ct-9466 36 22 54.5 54.5 NUM ct-9466 36 23 trat trat PROPN ct-9466 36 24 escape escape NOUN ct-9466 36 25 from from ADP ct-9466 36 26 host host NOUN ct-9466 36 27 defenses defense NOUN ct-9466 36 28 47.8 47.8 NUM ct-9466 36 29 sfad sfad NOUN ct-9466 36 30 / / SYM ct-9466 36 31 e e NOUN ct-9466 36 32 adhesin adhesin NOUN ct-9466 36 33 34.8 34.8 NUM ct-9466 36 34 tsh tsh NOUN ct-9466 36 35 adhesin adhesin NOUN ct-9466 36 36 34.8 34.8 NUM ct-9466 36 37 cnf-1 cnf-1 ADV ct-9466 36 38 toxin toxin NOUN ct-9466 36 39 26.1 26.1 NUM ct-9466 36 40 pape pape NOUN ct-9466 36 41 / / SYM ct-9466 36 42 f f PROPN ct-9466 36 43 adhesin adhesin PROPN ct-9466 36 44 21.7 21.7 NUM ct-9466 36 45 iss iss PROPN ct-9466 36 46 escape escape NOUN ct-9466 36 47 from from ADP ct-9466 36 48 host host NOUN ct-9466 36 49 defenses defense NOUN ct-9466 36 50 21.7 21.7 NUM ct-9466 36 51 iuta iuta ADJ ct-9466 36 52 aerobactin aerobactin NOUN ct-9466 36 53 system system NOUN ct-9466 36 54 17.4 17.4 NUM ct-9466 36 55 ompt ompt ADJ ct-9466 36 56 escape escape NOUN ct-9466 36 57 from from ADP ct-9466 36 58 host host NOUN ct-9466 36 59 defenses defense NOUN ct-9466 36 60 17.4 17.4 NUM ct-9466 36 61 cvac cvac NOUN ct-9466 36 62 escape escape NOUN ct-9466 36 63 from from ADP ct-9466 36 64 host host NOUN ct-9466 36 65 defense defense NOUN ct-9466 36 66 17.4 17.4 NUM ct-9466 36 67 hlyf hlyf PROPN ct-9466 36 68 toxin toxin PROPN ct-9466 36 69 17.4 17.4 NUM ct-9466 36 70 iucd iucd PROPN ct-9466 36 71 aerobactin aerobactin NOUN ct-9466 36 72 system system NOUN ct-9466 36 73 17.4 17.4 NUM ct-9466 36 74 iucc iucc ADP ct-9466 36 75 aerobactin aerobactin NOUN ct-9466 36 76 system system NOUN ct-9466 36 77 13.0 13.0 NUM ct-9466 36 78 asta asta PROPN ct-9466 36 79 toxin toxin NOUN ct-9466 36 80 13.0 13.0 NUM ct-9466 36 81 papgii papgii NOUN ct-9466 36 82 adhesin adhesin NOUN ct-9466 36 83 4.3 4.3 NUM ct-9466 36 84 at at ADP ct-9466 36 85 high high ADJ ct-9466 36 86 concentrations concentration NOUN ct-9466 36 87 , , PUNCT ct-9466 36 88 hlya hlya ADJ ct-9466 36 89 is be AUX ct-9466 36 90 able able ADJ ct-9466 36 91 to to PART ct-9466 36 92 lyse lyse VERB ct-9466 36 93 erythrocytes erythrocyte NOUN ct-9466 36 94 and and CCONJ ct-9466 36 95 nucleated nucleated ADJ ct-9466 36 96 host host NOUN ct-9466 36 97 cells cell NOUN ct-9466 36 98 . . PUNCT ct-9466 37 1 at at ADP ct-9466 37 2 low low ADJ ct-9466 37 3 ( ( PUNCT ct-9466 37 4 sublytic sublytic ADJ ct-9466 37 5 ) ) PUNCT ct-9466 37 6 concentrations concentration NOUN ct-9466 37 7 , , PUNCT ct-9466 37 8 hlya hlya PROPN ct-9466 37 9 can can AUX ct-9466 37 10 disrupt disrupt VERB ct-9466 37 11 the the DET ct-9466 37 12 immune immune ADJ ct-9466 37 13 signalling signal VERB ct-9466 37 14 and and CCONJ ct-9466 37 15 cytoskeletal cytoskeletal ADJ ct-9466 37 16 components.31 components.31 PROPN ct-9466 37 17 endometrial endometrial ADJ ct-9466 37 18 epithelial epithelial ADJ ct-9466 37 19 cells cell NOUN ct-9466 37 20 had have VERB ct-9466 37 21 high high ADJ ct-9466 37 22 sensitivity sensitivity NOUN ct-9466 37 23 to to ADP ct-9466 37 24 cytotoxic cytotoxic ADJ ct-9466 37 25 effect effect NOUN ct-9466 37 26 of of ADP ct-9466 37 27 hlya hlya ADJ ct-9466 37 28 , , PUNCT ct-9466 37 29 suggesting suggest VERB ct-9466 37 30 that that SCONJ ct-9466 37 31 β β NOUN ct-9466 37 32 - - ADJ ct-9466 37 33 hemolytic hemolytic ADJ ct-9466 37 34 e. e. PROPN ct-9466 37 35 coli coli PROPN ct-9466 37 36 induces induce VERB ct-9466 37 37 earlier early ADJ ct-9466 37 38 damage damage NOUN ct-9466 37 39 to to ADP ct-9466 37 40 the the DET ct-9466 37 41 epithelial epithelial ADJ ct-9466 37 42 glandular glandular ADJ ct-9466 37 43 cells cell NOUN ct-9466 37 44 than than ADP ct-9466 37 45 nonhemolytic nonhemolytic ADJ ct-9466 37 46 e. e. PROPN ct-9466 37 47 coli coli PROPN ct-9466 37 48 strains.32 strains.32 ADJ ct-9466 37 49 diagnosis diagnosis NOUN ct-9466 37 50 a a DET ct-9466 37 51 presumptive presumptive ADJ ct-9466 37 52 diagnosis diagnosis NOUN ct-9466 37 53 of of ADP ct-9466 37 54 pyometra pyometra NOUN ct-9466 37 55 is be AUX ct-9466 37 56 based base VERB ct-9466 37 57 on on ADP ct-9466 37 58 clinical clinical ADJ ct-9466 37 59 signs sign NOUN ct-9466 37 60 and and CCONJ ct-9466 37 61 laboratory laboratory NOUN ct-9466 37 62 test test NOUN ct-9466 37 63 results result NOUN ct-9466 37 64 , , PUNCT ct-9466 37 65 with with ADP ct-9466 37 66 a a DET ct-9466 37 67 confirmatory confirmatory NOUN ct-9466 37 68 diagnosis diagnosis NOUN ct-9466 37 69 made make VERB ct-9466 37 70 with with ADP ct-9466 37 71 b b NOUN ct-9466 37 72 - - PUNCT ct-9466 37 73 mode mode NOUN ct-9466 37 74 ultrasonography ultrasonography NOUN ct-9466 37 75 , , PUNCT ct-9466 37 76 with with ADP ct-9466 37 77 or or CCONJ ct-9466 37 78 without without ADP ct-9466 37 79 doppler doppler NOUN ct-9466 37 80 ultrasonography ultrasonography NOUN ct-9466 37 81 , , PUNCT ct-9466 37 82 detecting detect VERB ct-9466 37 83 an an DET ct-9466 37 84 enlarged enlarge VERB ct-9466 37 85 , , PUNCT ct-9466 37 86 fluid fluid NOUN ct-9466 37 87 - - PUNCT ct-9466 37 88 filled fill VERB ct-9466 37 89 uterus uterus NOUN ct-9466 37 90 with with ADP ct-9466 37 91 increased increase VERB ct-9466 37 92 blood blood NOUN ct-9466 37 93 flow flow NOUN ct-9466 37 94 . . PUNCT ct-9466 38 1 clinical clinical ADJ ct-9466 38 2 signs sign NOUN ct-9466 38 3 and and CCONJ ct-9466 38 4 laboratory laboratory NOUN ct-9466 38 5 test test NOUN ct-9466 38 6 results result VERB ct-9466 38 7 clinical clinical ADJ ct-9466 38 8 signs sign NOUN ct-9466 38 9 common common ADJ ct-9466 38 10 in in ADP ct-9466 38 11 pyometra pyometra NOUN ct-9466 38 12 include include VERB ct-9466 38 13 depression depression NOUN ct-9466 38 14 , , PUNCT ct-9466 38 15 anorexia anorexia ADJ ct-9466 38 16 , , PUNCT ct-9466 38 17 polydipsia polydipsia NOUN ct-9466 38 18 / / SYM ct-9466 38 19 polyuria polyuria NOUN ct-9466 38 20 , , PUNCT ct-9466 38 21 vomiting vomiting NOUN ct-9466 38 22 and and CCONJ ct-9466 38 23 vaginal vaginal ADJ ct-9466 38 24 discharge.5,33 discharge.5,33 PROPN ct-9466 38 25 - - PUNCT ct-9466 38 26 34 34 NUM ct-9466 38 27 anorexia anorexia ADJ ct-9466 38 28 , , PUNCT ct-9466 38 29 polydipsia polydipsia NOUN ct-9466 38 30 / / SYM ct-9466 38 31 polyuria polyuria NOUN ct-9466 38 32 , , PUNCT ct-9466 38 33 vomiting vomiting NOUN ct-9466 38 34 , , PUNCT ct-9466 38 35 and and CCONJ ct-9466 38 36 moderate moderate ADJ ct-9466 38 37 to to ADP ct-9466 38 38 severe severe ADJ ct-9466 38 39 dehydration dehydration NOUN ct-9466 38 40 did do AUX ct-9466 38 41 not not PART ct-9466 38 42 differ differ VERB ct-9466 38 43 significantly significantly ADV ct-9466 38 44 between between ADP ct-9466 38 45 cases case NOUN ct-9466 38 46 of of ADP ct-9466 38 47 open open ADJ ct-9466 38 48 and and CCONJ ct-9466 38 49 closed close VERB ct-9466 38 50 pyometra.3 pyometra.3 NOUN ct-9466 38 51 leukocytosis leukocytosis NOUN ct-9466 38 52 , , PUNCT ct-9466 38 53 with with ADP ct-9466 38 54 neutrophilia neutrophilia NOUN ct-9466 38 55 and and CCONJ ct-9466 38 56 left leave VERB ct-9466 38 57 shift shift NOUN ct-9466 38 58 , , PUNCT ct-9466 38 59 lymphopenia lymphopenia NOUN ct-9466 38 60 and and CCONJ ct-9466 38 61 monocytosis monocytosis NOUN ct-9466 38 62 are be AUX ct-9466 38 63 characteristic characteristic ADJ ct-9466 38 64 findings finding NOUN ct-9466 38 65 in in ADP ct-9466 38 66 pyometra pyometra NOUN ct-9466 38 67 , , PUNCT ct-9466 38 68 accompanied accompany VERB ct-9466 38 69 by by ADP ct-9466 38 70 normocytic normocytic ADJ ct-9466 38 71 , , PUNCT ct-9466 38 72 normochromic normochromic ADJ ct-9466 38 73 regenerative regenerative ADJ ct-9466 38 74 anemia.5 anemia.5 PROPN ct-9466 38 75 if if SCONJ ct-9466 38 76 present present ADJ ct-9466 38 77 , , PUNCT ct-9466 38 78 leukopenia leukopenia PROPN ct-9466 38 79 was be AUX ct-9466 38 80 the the DET ct-9466 38 81 most most ADV ct-9466 38 82 important important ADJ ct-9466 38 83 predictive predictive ADJ ct-9466 38 84 factor factor NOUN ct-9466 38 85 for for ADP ct-9466 38 86 prolonged prolonged ADJ ct-9466 38 87 postoperative postoperative ADJ ct-9466 38 88 hospitalization hospitalization NOUN ct-9466 38 89 , , PUNCT ct-9466 38 90 as as SCONJ ct-9466 38 91 it it PRON ct-9466 38 92 was be AUX ct-9466 38 93 associated associate VERB ct-9466 38 94 with with ADP ct-9466 38 95 an an DET ct-9466 38 96 18 18 NUM ct-9466 38 97 - - ADJ ct-9466 38 98 fold fold ADJ ct-9466 38 99 increased increase VERB ct-9466 38 100 risk risk NOUN ct-9466 38 101 of of ADP ct-9466 38 102 peritonitis.5 peritonitis.5 NOUN ct-9466 38 103 642clinical 642clinical PROPN ct-9466 38 104 theriogenology theriogenology NOUN ct-9466 39 1 • • NOUN ct-9466 39 2 volume volume NOUN ct-9466 39 3 11 11 NUM ct-9466 39 4 , , PUNCT ct-9466 39 5 number number NOUN ct-9466 39 6 4 4 NUM ct-9466 39 7 • • NOUN ct-9466 39 8 december december PROPN ct-9466 39 9 2019 2019 NUM ct-9466 39 10     SPACE ct-9466 39 11 concomitant concomitant ADJ ct-9466 39 12 cystitis cystitis NOUN ct-9466 39 13 , , PUNCT ct-9466 39 14 proteinuria proteinuria NOUN ct-9466 39 15 , , PUNCT ct-9466 39 16 and and CCONJ ct-9466 39 17 hypoalbuminemia hypoalbuminemia ADV ct-9466 39 18 usually usually ADV ct-9466 39 19 resolve resolve VERB ct-9466 39 20 after after ADP ct-9466 39 21 treatment treatment NOUN ct-9466 39 22 of of ADP ct-9466 39 23 the the DET ct-9466 39 24 pyometra pyometra NOUN ct-9466 39 25 , , PUNCT ct-9466 39 26 but but CCONJ ct-9466 39 27 severe severe ADJ ct-9466 39 28 proteinuria proteinuria NOUN ct-9466 39 29 that that PRON ct-9466 39 30 remains remain VERB ct-9466 39 31 may may AUX ct-9466 39 32 predispose predispose VERB ct-9466 39 33 to to ADP ct-9466 39 34 renal renal ADJ ct-9466 39 35 failure.35 failure.35 NOUN ct-9466 39 36 renal renal ADJ ct-9466 39 37 dysfunction dysfunction NOUN ct-9466 39 38 is be AUX ct-9466 39 39 common common ADJ ct-9466 39 40 . . PUNCT ct-9466 40 1 contributing contribute VERB ct-9466 40 2 factors factor NOUN ct-9466 40 3 to to ADP ct-9466 40 4 renal renal ADJ ct-9466 40 5 dysfunction dysfunction NOUN ct-9466 40 6 are be AUX ct-9466 40 7 : : PUNCT ct-9466 40 8 endotoxemia endotoxemia NOUN ct-9466 40 9 , , PUNCT ct-9466 40 10 glomerular glomerular ADJ ct-9466 40 11 dysfunction dysfunction NOUN ct-9466 40 12 , , PUNCT ct-9466 40 13 renal renal ADJ ct-9466 40 14 tubular tubular ADJ ct-9466 40 15 damage damage NOUN ct-9466 40 16 and and CCONJ ct-9466 40 17 decreased decrease VERB ct-9466 40 18 response response NOUN ct-9466 40 19 to to ADP ct-9466 40 20 antidiuretic antidiuretic ADJ ct-9466 40 21 hormone.35 hormone.35 NOUN ct-9466 40 22 - - PUNCT ct-9466 40 23 36 36 NUM ct-9466 40 24 blood blood NOUN ct-9466 40 25 urea urea NOUN ct-9466 40 26 nitrogen nitrogen NOUN ct-9466 40 27 > > X ct-9466 40 28 30 30 NUM ct-9466 40 29 mg mg PROPN ct-9466 40 30 / / SYM ct-9466 40 31 dl dl PROPN ct-9466 40 32 and and CCONJ ct-9466 40 33 creatinine creatinine PROPN ct-9466 40 34 concentrations concentration NOUN ct-9466 40 35 > > X ct-9466 40 36 1.5 1.5 NUM ct-9466 40 37 mg mg NUM ct-9466 40 38 / / SYM ct-9466 40 39 dl dl PROPN ct-9466 40 40 have have AUX ct-9466 40 41 been be AUX ct-9466 40 42 associated associate VERB ct-9466 40 43 with with ADP ct-9466 40 44 death.33 death.33 NOUN ct-9466 40 45 hypercholesterolemia hypercholesterolemia NOUN ct-9466 40 46 , , PUNCT ct-9466 40 47 increased increase VERB ct-9466 40 48 serum serum NOUN ct-9466 40 49 alkaline alkaline NOUN ct-9466 40 50 phosphatase phosphatase NOUN ct-9466 40 51 ( ( PUNCT ct-9466 40 52 alp alp PROPN ct-9466 40 53 ) ) PUNCT ct-9466 40 54 and and CCONJ ct-9466 40 55 coagulation coagulation NOUN ct-9466 40 56 impairment impairment NOUN ct-9466 40 57 have have AUX ct-9466 40 58 also also ADV ct-9466 40 59 been be AUX ct-9466 40 60 reported.36 reported.36 VERB ct-9466 40 61 - - PUNCT ct-9466 40 62 38 38 NUM ct-9466 40 63 systemic systemic ADJ ct-9466 40 64 inflammatory inflammatory ADJ ct-9466 40 65 response response NOUN ct-9466 40 66 syndrome syndrome NOUN ct-9466 40 67 in in ADP ct-9466 40 68 ~ ~ PUNCT ct-9466 40 69 50 50 NUM ct-9466 40 70 % % NOUN ct-9466 40 71 of of ADP ct-9466 40 72 cases case NOUN ct-9466 40 73 , , PUNCT ct-9466 40 74 pyometra pyometra NOUN ct-9466 40 75 can can AUX ct-9466 40 76 progress progress VERB ct-9466 40 77 into into ADP ct-9466 40 78 systemic systemic ADJ ct-9466 40 79 inflammatory inflammatory ADJ ct-9466 40 80 response response NOUN ct-9466 40 81 syndrome syndrome NOUN ct-9466 40 82 ( ( PUNCT ct-9466 40 83 sirs sirs PROPN ct-9466 40 84 ) ) PUNCT ct-9466 40 85 , , PUNCT ct-9466 40 86 a a DET ct-9466 40 87 form form NOUN ct-9466 40 88 of of ADP ct-9466 40 89 sepsis sepsis NOUN ct-9466 40 90 and and CCONJ ct-9466 40 91 endotoxemia endotoxemia NOUN ct-9466 40 92 that that PRON ct-9466 40 93 causes cause VERB ct-9466 40 94 multi multi ADJ ct-9466 40 95 - - ADJ ct-9466 40 96 organ organ ADJ ct-9466 40 97 dysfunctions.4,39 dysfunctions.4,39 NOUN ct-9466 40 98 - - PUNCT ct-9466 40 99 41 41 NUM ct-9466 40 100 sirs sir NOUN ct-9466 40 101 is be AUX ct-9466 40 102 more more ADV ct-9466 40 103 common common ADJ ct-9466 40 104 in in ADP ct-9466 40 105 dogs dog NOUN ct-9466 40 106 with with ADP ct-9466 40 107 closed closed ADJ ct-9466 40 108 pyometra pyometra NOUN ct-9466 40 109 than than ADP ct-9466 40 110 an an DET ct-9466 40 111 open open ADJ ct-9466 40 112 pyometra.3 pyometra.3 NOUN ct-9466 40 113 clinical clinical ADJ ct-9466 40 114 diagnostic diagnostic ADJ ct-9466 40 115 criteria criterion NOUN ct-9466 40 116 for for ADP ct-9466 40 117 sirs sir NOUN ct-9466 40 118 are be AUX ct-9466 40 119 nonspecific nonspecific ADJ ct-9466 40 120 but but CCONJ ct-9466 40 121 consist consist VERB ct-9466 40 122 of of ADP ct-9466 40 123 tachycardia tachycardia NOUN ct-9466 40 124 and and CCONJ ct-9466 40 125 tachypnea tachypnea NOUN ct-9466 40 126 , , PUNCT ct-9466 40 127 with with ADP ct-9466 40 128 a a DET ct-9466 40 129 similar similar ADJ ct-9466 40 130 hemogram hemogram NOUN ct-9466 40 131 as as SCONJ ct-9466 40 132 previously previously ADV ct-9466 40 133 described describe VERB ct-9466 40 134 for for ADP ct-9466 40 135 pyometra pyometra NOUN ct-9466 40 136 . . PUNCT ct-9466 41 1 in in ADP ct-9466 41 2 pyometra pyometra ADJ ct-9466 41 3 cases case NOUN ct-9466 41 4 diagnosed diagnose VERB ct-9466 41 5 with with ADP ct-9466 41 6 sirs sir NOUN ct-9466 41 7 , , PUNCT ct-9466 41 8 there there PRON ct-9466 41 9 are be VERB ct-9466 41 10 increases increase NOUN ct-9466 41 11 in in ADP ct-9466 41 12 blood blood NOUN ct-9466 41 13 concentrations concentration NOUN ct-9466 41 14 of of ADP ct-9466 41 15 : : PUNCT ct-9466 41 16 c c ADJ ct-9466 41 17 - - PUNCT ct-9466 41 18 reactive reactive ADJ ct-9466 41 19 protein protein NOUN ct-9466 41 20 ( ( PUNCT ct-9466 41 21 crp crp PROPN ct-9466 41 22 ) ) PUNCT ct-9466 41 23 , , PUNCT ct-9466 41 24 prostaglandin prostaglandin VERB ct-9466 41 25 15 15 NUM ct-9466 41 26 - - PUNCT ct-9466 41 27 ketodihydro ketodihydro NOUN ct-9466 41 28 - - PUNCT ct-9466 41 29 pgf2α pgf2α NOUN ct-9466 41 30 metabolite metabolite NOUN ct-9466 41 31 , , PUNCT ct-9466 41 32 serum serum NOUN ct-9466 41 33 amyloid amyloid NOUN ct-9466 41 34 a a PRON ct-9466 41 35 and and CCONJ ct-9466 41 36 haptoglobin haptoglobin NOUN ct-9466 41 37 . . PUNCT ct-9466 42 1 in in ADP ct-9466 42 2 addition addition NOUN ct-9466 42 3 , , PUNCT ct-9466 42 4 there there PRON ct-9466 42 5 were be VERB ct-9466 42 6 high high ADJ ct-9466 42 7 serum serum NOUN ct-9466 42 8 il8 il8 PROPN ct-9466 42 9 concentrations concentration NOUN ct-9466 42 10 in in ADP ct-9466 42 11 dogs dog NOUN ct-9466 42 12 sirs sir NOUN ct-9466 42 13 , , PUNCT ct-9466 42 14 suggesting suggest VERB ct-9466 42 15 il8 il8 PROPN ct-9466 42 16 may may AUX ct-9466 42 17 contribute contribute VERB ct-9466 42 18 to to ADP ct-9466 42 19 development development NOUN ct-9466 42 20 of of ADP ct-9466 42 21 systemic systemic ADJ ct-9466 42 22 disease disease NOUN ct-9466 42 23 in in ADP ct-9466 42 24 dogs dog NOUN ct-9466 42 25 with with ADP ct-9466 42 26 pyometra pyometra NOUN ct-9466 42 27 . . PUNCT ct-9466 43 1 despite despite SCONJ ct-9466 43 2 being be AUX ct-9466 43 3 potentially potentially ADV ct-9466 43 4 life life NOUN ct-9466 43 5 - - PUNCT ct-9466 43 6 threatening threatening ADJ ct-9466 43 7 , , PUNCT ct-9466 43 8 mortality mortality NOUN ct-9466 43 9 due due ADP ct-9466 43 10 to to ADP ct-9466 43 11 pyometra pyometra NOUN ct-9466 43 12 is be AUX ct-9466 43 13 relatively relatively ADV ct-9466 43 14 low low ADJ ct-9466 43 15 ( ( PUNCT ct-9466 43 16 3 3 NUM ct-9466 43 17 10%).5,42 10%).5,42 NUM ct-9466 43 18 ultrasonography ultrasonography NOUN ct-9466 43 19 in in ADP ct-9466 43 20 cases case NOUN ct-9466 43 21 of of ADP ct-9466 43 22 hyperplastic hyperplastic ADJ ct-9466 43 23 pyometra pyometra NOUN ct-9466 43 24 , , PUNCT ct-9466 43 25 proliferative proliferative ADJ ct-9466 43 26 response response NOUN ct-9466 43 27 can can AUX ct-9466 43 28 be be AUX ct-9466 43 29 detected detect VERB ct-9466 43 30 with with ADP ct-9466 43 31 b b NOUN ct-9466 43 32 - - PUNCT ct-9466 43 33 mode mode NOUN ct-9466 43 34 ultrasonography ultrasonography NOUN ct-9466 43 35 as as ADP ct-9466 43 36 a a DET ct-9466 43 37 thickened thicken VERB ct-9466 43 38 uterine uterine NOUN ct-9466 43 39 wall.15 wall.15 NOUN ct-9466 43 40 in in ADP ct-9466 43 41 addition addition NOUN ct-9466 43 42 , , PUNCT ct-9466 43 43 increased increase VERB ct-9466 43 44 expression expression NOUN ct-9466 43 45 of of ADP ct-9466 43 46 vegf vegf PROPN ct-9466 43 47 - - PUNCT ct-9466 43 48 a a PROPN ct-9466 43 49 and and CCONJ ct-9466 43 50 its its PRON ct-9466 43 51 receptors receptor NOUN ct-9466 43 52 during during ADP ct-9466 43 53 pyometra pyometra ADJ ct-9466 43 54 cause cause NOUN ct-9466 43 55 increased increase VERB ct-9466 43 56 blood blood NOUN ct-9466 43 57 flow flow NOUN ct-9466 43 58 ( ( PUNCT ct-9466 43 59 both both PRON ct-9466 43 60 peak peak VERB ct-9466 43 61 systolic systolic ADJ ct-9466 43 62 flow flow NOUN ct-9466 43 63 and and CCONJ ct-9466 43 64 end end VERB ct-9466 43 65 diastolic diastolic ADJ ct-9466 43 66 flow flow NOUN ct-9466 43 67 ) ) PUNCT ct-9466 43 68 from from ADP ct-9466 43 69 reduced reduce VERB ct-9466 43 70 vascular vascular NOUN ct-9466 43 71 resistance.15 resistance.15 NOUN ct-9466 43 72 females female NOUN ct-9466 43 73 diagnosed diagnose VERB ct-9466 43 74 with with ADP ct-9466 43 75 ceh ceh PROPN ct-9466 43 76 and and CCONJ ct-9466 43 77 mucometra mucometra PROPN ct-9466 43 78 should should AUX ct-9466 43 79 be be AUX ct-9466 43 80 monitored monitor VERB ct-9466 43 81 by by ADP ct-9466 43 82 doppler doppler NOUN ct-9466 43 83 ultrasound ultrasound NOUN ct-9466 43 84 during during ADP ct-9466 43 85 diestrus diestrus NOUN ct-9466 43 86 for for ADP ct-9466 43 87 early early ADJ ct-9466 43 88 pyometra pyometra ADJ ct-9466 43 89 identification identification NOUN ct-9466 43 90 , , PUNCT ct-9466 43 91 to to PART ct-9466 43 92 prevent prevent VERB ct-9466 43 93 development development NOUN ct-9466 43 94 of of ADP ct-9466 43 95 systemic systemic ADJ ct-9466 43 96 disease.15 disease.15 PROPN ct-9466 43 97 treatment treatment NOUN ct-9466 43 98 pyometra pyometra NOUN ct-9466 43 99 is be AUX ct-9466 43 100 an an DET ct-9466 43 101 emergency emergency NOUN ct-9466 43 102 condition condition NOUN ct-9466 43 103 that that PRON ct-9466 43 104 requires require VERB ct-9466 43 105 rapid rapid ADJ ct-9466 43 106 medical medical ADJ ct-9466 43 107 and/or and/or CCONJ ct-9466 43 108 surgical surgical ADJ ct-9466 43 109 intervention intervention NOUN ct-9466 43 110 to to PART ct-9466 43 111 minimize minimize VERB ct-9466 43 112 long long ADJ ct-9466 43 113 - - PUNCT ct-9466 43 114 term term NOUN ct-9466 43 115 health health NOUN ct-9466 43 116 complications complication NOUN ct-9466 43 117 and and CCONJ ct-9466 43 118 prevent prevent VERB ct-9466 43 119 death death NOUN ct-9466 43 120 . . PUNCT ct-9466 44 1 early early ADJ ct-9466 44 2 intervention intervention NOUN ct-9466 44 3 increases increase VERB ct-9466 44 4 chances chance NOUN ct-9466 44 5 of of ADP ct-9466 44 6 survival.43 survival.43 ADJ ct-9466 44 7 surgical surgical ADJ ct-9466 44 8 management management NOUN ct-9466 44 9 safest safe ADJ ct-9466 44 10 and and CCONJ ct-9466 44 11 most most ADV ct-9466 44 12 effective effective ADJ ct-9466 44 13 treatment treatment NOUN ct-9466 44 14 is be AUX ct-9466 44 15 surgical surgical ADJ ct-9466 44 16 removal removal NOUN ct-9466 44 17 of of ADP ct-9466 44 18 infected infected ADJ ct-9466 44 19 uterus uterus NOUN ct-9466 44 20 and and CCONJ ct-9466 44 21 ovaries ovary NOUN ct-9466 44 22 , , PUNCT ct-9466 44 23 ( ( PUNCT ct-9466 44 24 ovariohysterectomy ovariohysterectomy ADV ct-9466 44 25 ) ) PUNCT ct-9466 44 26 . . PUNCT ct-9466 45 1 anesthetic anesthetic ADJ ct-9466 45 2 risks risk NOUN ct-9466 45 3 associated associate VERB ct-9466 45 4 with with ADP ct-9466 45 5 this this DET ct-9466 45 6 surgery surgery NOUN ct-9466 45 7 are be AUX ct-9466 45 8 heightened heighten VERB ct-9466 45 9 due due ADP ct-9466 45 10 to to ADP ct-9466 45 11 a a DET ct-9466 45 12 compromised compromised ADJ ct-9466 45 13 status status NOUN ct-9466 45 14 . . PUNCT ct-9466 46 1 uterus uterus NOUN ct-9466 46 2 may may AUX ct-9466 46 3 be be AUX ct-9466 46 4 large large ADJ ct-9466 46 5 , , PUNCT ct-9466 46 6 friable friable ADJ ct-9466 46 7 , , PUNCT ct-9466 46 8 and and CCONJ ct-9466 46 9 prone prone ADJ ct-9466 46 10 to to ADP ct-9466 46 11 rupture rupture NOUN ct-9466 46 12 , , PUNCT ct-9466 46 13 so so CCONJ ct-9466 46 14 it it PRON ct-9466 46 15 is be AUX ct-9466 46 16 important important ADJ ct-9466 46 17 to to PART ct-9466 46 18 handle handle VERB ct-9466 46 19 it it PRON ct-9466 46 20 carefully carefully ADV ct-9466 46 21 . . PUNCT ct-9466 47 1 abdominal abdominal ADJ ct-9466 47 2 cavity cavity NOUN ct-9466 47 3 should should AUX ct-9466 47 4 be be AUX ct-9466 47 5 protected protect VERB ct-9466 47 6 from from ADP ct-9466 47 7 accidental accidental ADJ ct-9466 47 8 leakage leakage NOUN ct-9466 47 9 of of ADP ct-9466 47 10 purulent purulent ADJ ct-9466 47 11 material material NOUN ct-9466 47 12 from from ADP ct-9466 47 13 uterine uterine ADJ ct-9466 47 14 laceration laceration NOUN ct-9466 47 15 or or CCONJ ct-9466 47 16 uterine uterine ADJ ct-9466 47 17 tubes tube NOUN ct-9466 47 18 / / SYM ct-9466 47 19 ovarian ovarian ADJ ct-9466 47 20 bursa bursa NOUN ct-9466 47 21 opening opening NOUN ct-9466 47 22 . . PUNCT ct-9466 48 1 this this PRON ct-9466 48 2 is be AUX ct-9466 48 3 accomplished accomplish VERB ct-9466 48 4 by by ADP ct-9466 48 5 packing pack VERB ct-9466 48 6 off off ADP ct-9466 48 7 uterus uterus NOUN ct-9466 48 8 with with ADP ct-9466 48 9 moistened moisten VERB ct-9466 48 10 laparotomy laparotomy NOUN ct-9466 48 11 pads.43 pads.43 NOUN ct-9466 48 12 prior prior ADV ct-9466 48 13 to to ADP ct-9466 48 14 surgery surgery NOUN ct-9466 48 15 , , PUNCT ct-9466 48 16 patient patient NOUN ct-9466 48 17 is be AUX ct-9466 48 18 stabilized stabilize VERB ct-9466 48 19 with with ADP ct-9466 48 20 adequate adequate ADJ ct-9466 48 21 intravenous intravenous ADJ ct-9466 48 22 fluid fluid NOUN ct-9466 48 23 therapy therapy NOUN ct-9466 48 24 to to PART ct-9466 48 25 correct correct VERB ct-9466 48 26 hypotension hypotension NOUN ct-9466 48 27 ( ( PUNCT ct-9466 48 28 60 60 NUM ct-9466 48 29 ml ml NOUN ct-9466 48 30 / / SYM ct-9466 48 31 kg kg NOUN ct-9466 48 32 + + CCONJ ct-9466 48 33 % % NOUN ct-9466 48 34 dehydration dehydration NOUN ct-9466 48 35 x x PUNCT ct-9466 48 36 body body NOUN ct-9466 48 37 weight/100 weight/100 PROPN ct-9466 48 38 ) ) PUNCT ct-9466 48 39 , , PUNCT ct-9466 48 40 hypoperfusion hypoperfusion NOUN ct-9466 48 41 , , PUNCT ct-9466 48 42 shock shock NOUN ct-9466 48 43 , , PUNCT ct-9466 48 44 dehydration dehydration NOUN ct-9466 48 45 , , PUNCT ct-9466 48 46 acid acid NOUN ct-9466 48 47 - - PUNCT ct-9466 48 48 base base NOUN ct-9466 48 49 balance balance NOUN ct-9466 48 50 and and CCONJ ct-9466 48 51 electrolyte electrolyte NOUN ct-9466 48 52 abnormalities abnormality NOUN ct-9466 48 53 , , PUNCT ct-9466 48 54 coagulation coagulation NOUN ct-9466 48 55 disturbances disturbance NOUN ct-9466 48 56 , , PUNCT ct-9466 48 57 and and CCONJ ct-9466 48 58 organ organ NOUN ct-9466 48 59 dysfunctions.44 dysfunctions.44 NOUN ct-9466 48 60 intensive intensive ADJ ct-9466 48 61 postoperative postoperative ADJ ct-9466 48 62 monitoring monitoring NOUN ct-9466 48 63 is be AUX ct-9466 48 64 essential essential ADJ ct-9466 48 65 and and CCONJ ct-9466 48 66 in in ADP ct-9466 48 67 uncomplicated uncomplicated ADJ ct-9466 48 68 cases case NOUN ct-9466 48 69 , , PUNCT ct-9466 48 70 1 1 NUM ct-9466 48 71 to to PART ct-9466 48 72 2 2 NUM ct-9466 48 73 days day NOUN ct-9466 48 74 of of ADP ct-9466 48 75 postoperative postoperative ADJ ct-9466 48 76 hospitalization hospitalization NOUN ct-9466 48 77 is be AUX ct-9466 48 78 usually usually ADV ct-9466 48 79 adequate.43 adequate.43 ADJ ct-9466 48 80 broad broad ADJ ct-9466 48 81 - - PUNCT ct-9466 48 82 spectrum spectrum NOUN ct-9466 48 83 antibiotics antibiotic NOUN ct-9466 48 84 with with ADP ct-9466 48 85 minimal minimal ADJ ct-9466 48 86 nephrotoxicity nephrotoxicity NOUN ct-9466 48 87 are be AUX ct-9466 48 88 needed need VERB ct-9466 48 89 to to PART ct-9466 48 90 prevent prevent VERB ct-9466 48 91 septicemia septicemia NOUN ct-9466 48 92 ( ( PUNCT ct-9466 48 93 e.g. e.g. ADV ct-9466 48 94 amoxicillin amoxicillin NOUN ct-9466 48 95 - - PUNCT ct-9466 48 96 clavulanic clavulanic ADJ ct-9466 48 97 acid acid NOUN ct-9466 48 98 12.5 12.5 NUM ct-9466 48 99 mg mg NOUN ct-9466 48 100 / / SYM ct-9466 48 101 kg kg PROPN ct-9466 48 102 twice twice DET ct-9466 48 103 a a DET ct-9466 48 104 day day NOUN ct-9466 48 105 ) ) PUNCT ct-9466 48 106 . . PUNCT ct-9466 49 1 antibiotics antibiotic NOUN ct-9466 49 2 alone alone ADJ ct-9466 49 3 for for ADP ct-9466 49 4 treatment treatment NOUN ct-9466 49 5 of of ADP ct-9466 49 6 pyometra pyometra NOUN ct-9466 49 7 will will AUX ct-9466 49 8 improve improve VERB ct-9466 49 9 general general ADJ ct-9466 49 10 status status NOUN ct-9466 49 11 and and CCONJ ct-9466 49 12 may may AUX ct-9466 49 13 prevent prevent VERB ct-9466 49 14 progression progression NOUN ct-9466 49 15 but but CCONJ ct-9466 49 16 will will AUX ct-9466 49 17 not not PART ct-9466 49 18 resolve resolve VERB ct-9466 49 19 the the DET ct-9466 49 20 condition condition NOUN ct-9466 49 21 . . PUNCT ct-9466 50 1 antibiotics antibiotic NOUN ct-9466 50 2 should should AUX ct-9466 50 3 be be AUX ct-9466 50 4 continued continue VERB ct-9466 50 5 for for ADP ct-9466 50 6 > > X ct-9466 50 7 2 2 NUM ct-9466 50 8 weeks.45 weeks.45 VERB ct-9466 50 9 antibiotic antibiotic ADJ ct-9466 50 10 drug drug NOUN ct-9466 50 11 selection selection NOUN ct-9466 50 12 and and CCONJ ct-9466 50 13 route route NOUN ct-9466 50 14 of of ADP ct-9466 50 15 administration administration NOUN ct-9466 50 16 should should AUX ct-9466 50 17 be be AUX ct-9466 50 18 based base VERB ct-9466 50 19 on on ADP ct-9466 50 20 bacterial bacterial ADJ ct-9466 50 21 culture culture NOUN ct-9466 50 22 , , PUNCT ct-9466 50 23 sensitivity sensitivity NOUN ct-9466 50 24 tests test NOUN ct-9466 50 25 and and CCONJ ct-9466 50 26 pharmacokinetics pharmacokinetic NOUN ct-9466 50 27 for for ADP ct-9466 50 28 achieving achieve VERB ct-9466 50 29 optimal optimal ADJ ct-9466 50 30 effect.43 effect.43 NOUN ct-9466 50 31 the the DET ct-9466 50 32 initial initial ADJ ct-9466 50 33 choice choice NOUN ct-9466 50 34 of of ADP ct-9466 50 35 antibiotics antibiotic NOUN ct-9466 50 36 should should AUX ct-9466 50 37 be be AUX ct-9466 50 38 effective effective ADJ ct-9466 50 39 against against ADP ct-9466 50 40 the the DET ct-9466 50 41 most most ADV ct-9466 50 42 likely likely ADJ ct-9466 50 43 pathogen pathogen NOUN ct-9466 50 44 ( ( PUNCT ct-9466 50 45 e. e. PROPN ct-9466 50 46 coli coli PROPN ct-9466 50 47 ) ) PUNCT ct-9466 50 48 and and CCONJ ct-9466 50 49 adjusted adjust VERB ct-9466 50 50 after after ADP ct-9466 50 51 culture culture NOUN ct-9466 50 52 and and CCONJ ct-9466 50 53 sensitivity sensitivity NOUN ct-9466 50 54 results result NOUN ct-9466 50 55 to to ADP ct-9466 50 56 a a DET ct-9466 50 57 narrow narrow ADJ ct-9466 50 58 - - PUNCT ct-9466 50 59 spectrum spectrum NOUN ct-9466 50 60 alternative.43,46 alternative.43,46 NOUN ct-9466 50 61 in in ADP ct-9466 50 62 1 1 NUM ct-9466 50 63 study study NOUN ct-9466 50 64 , , PUNCT ct-9466 50 65 90 90 NUM ct-9466 50 66 % % NOUN ct-9466 50 67 of of ADP ct-9466 50 68 e. e. PROPN ct-9466 50 69 coli coli PROPN ct-9466 50 70 pyometra pyometra PROPN ct-9466 50 71 isolates isolate NOUN ct-9466 50 72 were be AUX ct-9466 50 73 sensitive sensitive ADJ ct-9466 50 74 to to ADP ct-9466 50 75 ampicillin.47 ampicillin.47 PROPN ct-9466 50 76 intravenous intravenous PROPN ct-9466 50 77 administration administration NOUN ct-9466 50 78 may may AUX ct-9466 50 79 be be AUX ct-9466 50 80 superior superior ADJ ct-9466 50 81 to to PART ct-9466 50 82 prevent prevent VERB ct-9466 50 83 systemic systemic ADJ ct-9466 50 84 effects effect NOUN ct-9466 50 85 of of ADP ct-9466 50 86 sepsis.46 sepsis.46 PROPN ct-9466 50 87 643 643 NUM ct-9466 50 88 clinical clinical ADJ ct-9466 50 89 theriogenology theriogenology NOUN ct-9466 50 90 • • NOUN ct-9466 50 91 volume volume NOUN ct-9466 50 92 11 11 NUM ct-9466 50 93 , , PUNCT ct-9466 50 94 number number NOUN ct-9466 50 95 4 4 NUM ct-9466 50 96 • • NOUN ct-9466 50 97 december december PROPN ct-9466 50 98 2019 2019 NUM ct-9466 50 99     SPACE ct-9466 50 100 medical medical ADJ ct-9466 50 101 management management NOUN ct-9466 50 102 medical medical ADJ ct-9466 50 103 management management NOUN ct-9466 50 104 of of ADP ct-9466 50 105 pyometra pyometra NOUN ct-9466 50 106 may may AUX ct-9466 50 107 be be AUX ct-9466 50 108 indicated indicate VERB ct-9466 50 109 to to PART ct-9466 50 110 improve improve VERB ct-9466 50 111 the the DET ct-9466 50 112 general general ADJ ct-9466 50 113 status status NOUN ct-9466 50 114 of of ADP ct-9466 50 115 the the DET ct-9466 50 116 bitch bitch NOUN ct-9466 50 117 prior prior ADV ct-9466 50 118 to to ADP ct-9466 50 119 surgery surgery NOUN ct-9466 50 120 or or CCONJ ct-9466 50 121 in in ADP ct-9466 50 122 the the DET ct-9466 50 123 bitch bitch NOUN ct-9466 50 124 that that PRON ct-9466 50 125 can can AUX ct-9466 50 126 not not PART ct-9466 50 127 undergo undergo VERB ct-9466 50 128 general general ADJ ct-9466 50 129 anesthesia anesthesia NOUN ct-9466 50 130 for for ADP ct-9466 50 131 other other ADJ ct-9466 50 132 reasons reason NOUN ct-9466 50 133 . . PUNCT ct-9466 51 1 in in ADP ct-9466 51 2 addition addition NOUN ct-9466 51 3 , , PUNCT ct-9466 51 4 medical medical ADJ ct-9466 51 5 management management NOUN ct-9466 51 6 may may AUX ct-9466 51 7 be be AUX ct-9466 51 8 indicated indicate VERB ct-9466 51 9 for for ADP ct-9466 51 10 treatment treatment NOUN ct-9466 51 11 of of ADP ct-9466 51 12 pyometra pyometra NOUN ct-9466 51 13 in in ADP ct-9466 51 14 valuable valuable ADJ ct-9466 51 15 breeding breeding NOUN ct-9466 51 16 bitches bitch NOUN ct-9466 51 17 . . PUNCT ct-9466 52 1 however however ADV ct-9466 52 2 , , PUNCT ct-9466 52 3 the the DET ct-9466 52 4 efficacy efficacy NOUN ct-9466 52 5 of of ADP ct-9466 52 6 medical medical ADJ ct-9466 52 7 management management NOUN ct-9466 52 8 depends depend VERB ct-9466 52 9 on on ADP ct-9466 52 10 clinical clinical ADJ ct-9466 52 11 presentation presentation NOUN ct-9466 52 12 ( ( PUNCT ct-9466 52 13 e.g. e.g. ADV ct-9466 52 14 stability stability NOUN ct-9466 52 15 of of ADP ct-9466 52 16 patient patient NOUN ct-9466 52 17 , , PUNCT ct-9466 52 18 patency patency NOUN ct-9466 52 19 of of ADP ct-9466 52 20 cervix cervix NOUN ct-9466 52 21 ) ) PUNCT ct-9466 52 22 and and CCONJ ct-9466 52 23 presence presence NOUN ct-9466 52 24 of of ADP ct-9466 52 25 underlying underlie VERB ct-9466 52 26 problems problem NOUN ct-9466 52 27 ( ( PUNCT ct-9466 52 28 e.g. e.g. ADV ct-9466 52 29 cystic cystic ADJ ct-9466 52 30 endometrial endometrial ADJ ct-9466 52 31 hyperplasia hyperplasia NOUN ct-9466 52 32 , , PUNCT ct-9466 52 33 ovarian ovarian ADJ ct-9466 52 34 cyst cyst NOUN ct-9466 52 35 or or CCONJ ct-9466 52 36 tumor).48 tumor).48 VERB ct-9466 52 37 goal goal NOUN ct-9466 52 38 of of ADP ct-9466 52 39 medical medical ADJ ct-9466 52 40 management management NOUN ct-9466 52 41 is be AUX ct-9466 52 42 to to PART ct-9466 52 43 evacuate evacuate VERB ct-9466 52 44 uterine uterine ADJ ct-9466 52 45 contents content NOUN ct-9466 52 46 by by ADP ct-9466 52 47 dilating dilate VERB ct-9466 52 48 cervix cervix NOUN ct-9466 52 49 and and CCONJ ct-9466 52 50 stimulating stimulate VERB ct-9466 52 51 myometrial myometrial ADJ ct-9466 52 52 contractility contractility NOUN ct-9466 52 53 . . PUNCT ct-9466 53 1 protocols protocol NOUN ct-9466 53 2 using use VERB ct-9466 53 3 prostaglandin prostaglandin NOUN ct-9466 53 4 f2α f2α PROPN ct-9466 53 5 ( ( PUNCT ct-9466 53 6 pgf2α pgf2α ADJ ct-9466 53 7 ) ) PUNCT ct-9466 53 8 and and CCONJ ct-9466 53 9 progesterone progesterone NOUN ct-9466 53 10 antagonists antagonist NOUN ct-9466 53 11 ( ( PUNCT ct-9466 53 12 aglepristone aglepristone ADJ ct-9466 53 13 ) ) PUNCT ct-9466 53 14 are be AUX ct-9466 53 15 described describe VERB ct-9466 53 16 in in ADP ct-9466 53 17 table table NOUN ct-9466 53 18 3 3 NUM ct-9466 53 19 . . PUNCT ct-9466 54 1 aglepristone aglepristone PROPN ct-9466 54 2 can can AUX ct-9466 54 3 be be AUX ct-9466 54 4 used use VERB ct-9466 54 5 to to PART ct-9466 54 6 successfully successfully ADV ct-9466 54 7 treat treat VERB ct-9466 54 8 either either CCONJ ct-9466 54 9 open open ADJ ct-9466 54 10 or or CCONJ ct-9466 54 11 closed closed ADJ ct-9466 54 12 pyometras pyometra NOUN ct-9466 54 13 , , PUNCT ct-9466 54 14 with with ADP ct-9466 54 15 cervical cervical ADJ ct-9466 54 16 opening opening NOUN ct-9466 54 17 occurring occur VERB ct-9466 54 18 within within ADP ct-9466 54 19 25.8 25.8 NUM ct-9466 54 20 ± ± NUM ct-9466 54 21 12.3 12.3 NUM ct-9466 54 22 hours hour NOUN ct-9466 54 23 after after SCONJ ct-9466 54 24 initial initial ADJ ct-9466 54 25 treatment.16,48 treatment.16,48 NOUN ct-9466 54 26 - - PUNCT ct-9466 54 27 50 50 NUM ct-9466 54 28 however however ADV ct-9466 54 29 , , PUNCT ct-9466 54 30 pgf2α pgf2α X ct-9466 54 31 treatment treatment NOUN ct-9466 54 32 is be AUX ct-9466 54 33 contraindicated contraindicate VERB ct-9466 54 34 in in ADP ct-9466 54 35 closed closed ADJ ct-9466 54 36 pyometra pyometra NOUN ct-9466 54 37 due due ADP ct-9466 54 38 to to ADP ct-9466 54 39 its its PRON ct-9466 54 40 potential potential NOUN ct-9466 54 41 for for ADP ct-9466 54 42 forcing force VERB ct-9466 54 43 purulent purulent ADJ ct-9466 54 44 material material NOUN ct-9466 54 45 retrograding retrograde VERB ct-9466 54 46 to to ADP ct-9466 54 47 uterine uterine ADJ ct-9466 54 48 tubes tube NOUN ct-9466 54 49 through through ADP ct-9466 54 50 ovarian ovarian ADJ ct-9466 54 51 bursae bursa NOUN ct-9466 54 52 and and CCONJ ct-9466 54 53 into into ADP ct-9466 54 54 peritoneal peritoneal ADJ ct-9466 54 55 cavity cavity NOUN ct-9466 54 56 or or CCONJ ct-9466 54 57 through through ADP ct-9466 54 58 rupture rupture NOUN ct-9466 54 59 of of ADP ct-9466 54 60 uterine uterine ADJ ct-9466 54 61 wall.51 wall.51 PROPN ct-9466 54 62 administration administration NOUN ct-9466 54 63 of of ADP ct-9466 54 64 prostaglandin prostaglandin PROPN ct-9466 54 65 e2 e2 PROPN ct-9466 54 66 ( ( PUNCT ct-9466 54 67 either either CCONJ ct-9466 54 68 intravaginally intravaginally ADV ct-9466 54 69 or or CCONJ ct-9466 54 70 orally orally ADV ct-9466 54 71 ) ) PUNCT ct-9466 54 72 may may AUX ct-9466 54 73 result result VERB ct-9466 54 74 in in ADP ct-9466 54 75 cervical cervical ADJ ct-9466 54 76 relaxation relaxation NOUN ct-9466 54 77 sufficient sufficient ADJ ct-9466 54 78 to to PART ct-9466 54 79 allow allow VERB ct-9466 54 80 pgf2α pgf2α PROPN ct-9466 55 1 but but CCONJ ct-9466 55 2 this this PRON ct-9466 55 3 remains remain VERB ct-9466 55 4 to to PART ct-9466 55 5 be be AUX ct-9466 55 6 studied.45,52 studied.45,52 ADJ ct-9466 55 7 intrauterine intrauterine ADJ ct-9466 55 8 drainage drainage NOUN ct-9466 55 9 and and CCONJ ct-9466 55 10 lavage lavage NOUN ct-9466 55 11 via via ADP ct-9466 55 12 transcervical transcervical ADJ ct-9466 55 13 catheterization catheterization NOUN ct-9466 55 14 followed follow VERB ct-9466 55 15 by by ADP ct-9466 55 16 instillation instillation NOUN ct-9466 55 17 of of ADP ct-9466 55 18 intrauterine intrauterine ADJ ct-9466 55 19 antibiotics antibiotic NOUN ct-9466 55 20 may may AUX ct-9466 55 21 facilitate facilitate VERB ct-9466 55 22 recovery recovery NOUN ct-9466 55 23 in in ADP ct-9466 55 24 refractory refractory NOUN ct-9466 55 25 cases.53 cases.53 PROPN ct-9466 55 26 - - PUNCT ct-9466 55 27 56 56 NUM ct-9466 55 28 with with ADP ct-9466 55 29 respect respect NOUN ct-9466 55 30 to to ADP ct-9466 55 31 complications complication NOUN ct-9466 55 32 of of ADP ct-9466 55 33 medical medical ADJ ct-9466 55 34 management management NOUN ct-9466 55 35 , , PUNCT ct-9466 55 36 ~ ~ PUNCT ct-9466 55 37 20 20 NUM ct-9466 55 38 % % NOUN ct-9466 55 39 of of ADP ct-9466 55 40 pyometra pyometra ADJ ct-9466 55 41 patients patient NOUN ct-9466 55 42 experienced experience VERB ct-9466 55 43 complications complication NOUN ct-9466 55 44 , , PUNCT ct-9466 55 45 most most ADV ct-9466 55 46 commonly commonly ADV ct-9466 55 47 peritonitis peritonitis NOUN ct-9466 55 48 ( ( PUNCT ct-9466 55 49 10 10 NUM ct-9466 55 50 12 12 NUM ct-9466 55 51 % % NOUN ct-9466 55 52 of of ADP ct-9466 55 53 cases case NOUN ct-9466 55 54 ) ) PUNCT ct-9466 55 55 followed follow VERB ct-9466 55 56 by by ADP ct-9466 55 57 chronic chronic ADJ ct-9466 55 58 pyelonephritis pyelonephritis NOUN ct-9466 55 59 , , PUNCT ct-9466 55 60 urinary urinary ADJ ct-9466 55 61 tract tract NOUN ct-9466 55 62 infection infection NOUN ct-9466 55 63 , , PUNCT ct-9466 55 64 myocarditis myocarditis PROPN ct-9466 55 65 , , PUNCT ct-9466 55 66 and and CCONJ ct-9466 55 67 disseminated disseminate VERB ct-9466 55 68 intravascular intravascular ADJ ct-9466 55 69 coagulation.3,5,40,57 coagulation.3,5,40,57 NOUN ct-9466 55 70 - - PUNCT ct-9466 55 71 59 59 NUM ct-9466 55 72 persistent persistent ADJ ct-9466 55 73 proteinuria proteinuria NOUN ct-9466 55 74 and and CCONJ ct-9466 55 75 urinary urinary ADJ ct-9466 55 76 protein protein NOUN ct-9466 55 77 - - PUNCT ct-9466 55 78 creatinine creatinine NOUN ct-9466 55 79 indicate indicate VERB ct-9466 55 80 renal renal ADJ ct-9466 55 81 disease disease NOUN ct-9466 55 82 that that PRON ct-9466 55 83 requires require VERB ct-9466 55 84 special special ADJ ct-9466 55 85 attention.35 attention.35 NOUN ct-9466 55 86 other other ADJ ct-9466 55 87 reported report VERB ct-9466 55 88 complications complication NOUN ct-9466 55 89 include include VERB ct-9466 55 90 uveitis uveitis NOUN ct-9466 55 91 , , PUNCT ct-9466 55 92 intracranial intracranial ADJ ct-9466 55 93 thromboemboli thromboemboli NOUN ct-9466 55 94 , , PUNCT ct-9466 55 95 bacterial bacterial ADJ ct-9466 55 96 osteomyelitis osteomyelitis NOUN ct-9466 55 97 , , PUNCT ct-9466 55 98 pericarditis pericarditis NOUN ct-9466 55 99 , , PUNCT ct-9466 55 100 septic septic ADJ ct-9466 55 101 arthritis arthritis NOUN ct-9466 55 102 , , PUNCT ct-9466 55 103 incisional incisional ADJ ct-9466 55 104 swelling swelling NOUN ct-9466 55 105 , , PUNCT ct-9466 55 106 dehiscence dehiscence NOUN ct-9466 55 107 , , PUNCT ct-9466 55 108 urethral urethral ADJ ct-9466 55 109 trauma trauma NOUN ct-9466 55 110 , , PUNCT ct-9466 55 111 recurrent recurrent ADJ ct-9466 55 112 estrus estrus NOUN ct-9466 55 113 , , PUNCT ct-9466 55 114 uterine uterine ADJ ct-9466 55 115 stump stump NOUN ct-9466 55 116 pyometra pyometra NOUN ct-9466 55 117 , , PUNCT ct-9466 55 118 fistulous fistulous ADJ ct-9466 55 119 tracts tract NOUN ct-9466 55 120 , , PUNCT ct-9466 55 121 urinary urinary ADJ ct-9466 55 122 incontinence incontinence NOUN ct-9466 55 123 , , PUNCT ct-9466 55 124 septic septic ADJ ct-9466 55 125 shock shock NOUN ct-9466 55 126 and and CCONJ ct-9466 55 127 death.35,58 death.35,58 NOUN ct-9466 55 128 - - PUNCT ct-9466 55 129 59 59 NUM ct-9466 55 130 severe severe ADJ ct-9466 55 131 complications complication NOUN ct-9466 55 132 associated associate VERB ct-9466 55 133 with with ADP ct-9466 55 134 pyometra pyometra NOUN ct-9466 55 135 include include VERB ct-9466 55 136 sepsis sepsis NOUN ct-9466 55 137 , , PUNCT ct-9466 55 138 septic septic ADJ ct-9466 55 139 shock shock NOUN ct-9466 55 140 , , PUNCT ct-9466 55 141 peritonitis peritonitis NOUN ct-9466 55 142 , , PUNCT ct-9466 55 143 disseminated disseminate VERB ct-9466 55 144 bacterial bacterial ADJ ct-9466 55 145 infection infection NOUN ct-9466 55 146 organ organ NOUN ct-9466 55 147 dysfunctions dysfunction NOUN ct-9466 55 148 and and CCONJ ct-9466 55 149 death.58,60 death.58,60 ADJ ct-9466 55 150 - - PUNCT ct-9466 55 151 61 61 NUM ct-9466 55 152 proportion proportion NOUN ct-9466 55 153 of of ADP ct-9466 55 154 dogs dog NOUN ct-9466 55 155 with with ADP ct-9466 55 156 complications complication NOUN ct-9466 55 157 did do AUX ct-9466 55 158 not not PART ct-9466 55 159 differ differ VERB ct-9466 55 160 significantly significantly ADV ct-9466 55 161 between between ADP ct-9466 55 162 open open ADJ ct-9466 55 163 and and CCONJ ct-9466 55 164 closed closed ADJ ct-9466 55 165 pyometras.3 pyometras.3 NOUN ct-9466 55 166 despite despite SCONJ ct-9466 55 167 this this PRON ct-9466 55 168 , , PUNCT ct-9466 55 169 it it PRON ct-9466 55 170 is be AUX ct-9466 55 171 prudent prudent ADJ ct-9466 55 172 to to PART ct-9466 55 173 obtain obtain VERB ct-9466 55 174 signed sign VERB ct-9466 55 175 owner owner NOUN ct-9466 55 176 consent consent NOUN ct-9466 55 177 prior prior ADV ct-9466 55 178 to to ADP ct-9466 55 179 treatment treatment NOUN ct-9466 55 180 , , PUNCT ct-9466 55 181 regarding regard VERB ct-9466 55 182 potential potential ADJ ct-9466 55 183 risks risk NOUN ct-9466 55 184 necessary necessary ADJ ct-9466 55 185 to to PART ct-9466 55 186 obtain obtain VERB ct-9466 55 187 prior prior ADV ct-9466 55 188 to to ADP ct-9466 55 189 extra extra ADJ ct-9466 55 190 label label NOUN ct-9466 55 191 drug drug NOUN ct-9466 55 192 usage.3 usage.3 PROPN ct-9466 55 193 in in ADP ct-9466 55 194 addition addition NOUN ct-9466 55 195 , , PUNCT ct-9466 55 196 aglepristone aglepristone ADV ct-9466 55 197 is be AUX ct-9466 55 198 not not PART ct-9466 55 199 currently currently ADV ct-9466 55 200 approved approve VERB ct-9466 55 201 for for ADP ct-9466 55 202 use use NOUN ct-9466 55 203 in in ADP ct-9466 55 204 north north PROPN ct-9466 55 205 america america PROPN ct-9466 55 206 . . PUNCT ct-9466 56 1 prognosis prognosis NOUN ct-9466 56 2 following follow VERB ct-9466 56 3 medical medical ADJ ct-9466 56 4 management management NOUN ct-9466 56 5 of of ADP ct-9466 56 6 pyometra pyometra NOUN ct-9466 56 7 with with ADP ct-9466 56 8 pgf2α pgf2α PROPN ct-9466 56 9 or or CCONJ ct-9466 56 10 aglepristone aglepristone ADJ ct-9466 56 11 , , PUNCT ct-9466 56 12 prognosis prognosis NOUN ct-9466 56 13 for for ADP ct-9466 56 14 survival survival NOUN ct-9466 56 15 and and CCONJ ct-9466 56 16 fertility fertility NOUN ct-9466 56 17 is be AUX ct-9466 56 18 considered consider VERB ct-9466 56 19 guarded guard VERB ct-9466 56 20 to to ADP ct-9466 56 21 good good ADJ ct-9466 56 22 . . PUNCT ct-9466 57 1 average average ADJ ct-9466 57 2 fertility fertility NOUN ct-9466 57 3 rate rate NOUN ct-9466 57 4 following follow VERB ct-9466 57 5 medical medical ADJ ct-9466 57 6 management management NOUN ct-9466 57 7 is be AUX ct-9466 57 8 70 70 NUM ct-9466 57 9 % % NOUN ct-9466 57 10 ( ( PUNCT ct-9466 57 11 range range NOUN ct-9466 57 12 , , PUNCT ct-9466 57 13 14 14 NUM ct-9466 57 14 100%).43,51,62 100%).43,51,62 NOUN ct-9466 57 15 - - SYM ct-9466 57 16 64 64 NUM ct-9466 57 17 fertility fertility NOUN ct-9466 57 18 rates rate NOUN ct-9466 57 19 are be AUX ct-9466 57 20 even even ADV ct-9466 57 21 higher high ADJ ct-9466 57 22 in in ADP ct-9466 57 23 younger young ADJ ct-9466 57 24 ( ( PUNCT ct-9466 57 25 < < X ct-9466 57 26 5 5 NUM ct-9466 57 27 years year NOUN ct-9466 57 28 ) ) PUNCT ct-9466 57 29 bitches bitch NOUN ct-9466 57 30 and and CCONJ ct-9466 57 31 those those PRON ct-9466 57 32 that that PRON ct-9466 57 33 have have VERB ct-9466 57 34 no no DET ct-9466 57 35 other other ADJ ct-9466 57 36 uterine uterine NOUN ct-9466 57 37 or or CCONJ ct-9466 57 38 ovarian ovarian ADJ ct-9466 57 39 pathology.50 pathology.50 NOUN ct-9466 57 40 average average NOUN ct-9466 57 41 reported report VERB ct-9466 57 42 long long ADJ ct-9466 57 43 - - PUNCT ct-9466 57 44 term term NOUN ct-9466 57 45 success success NOUN ct-9466 57 46 ( ( PUNCT ct-9466 57 47 resolution resolution NOUN ct-9466 57 48 of of ADP ct-9466 57 49 clinical clinical ADJ ct-9466 57 50 illness illness NOUN ct-9466 57 51 ) ) PUNCT ct-9466 57 52 following follow VERB ct-9466 57 53 medical medical ADJ ct-9466 57 54 management management NOUN ct-9466 57 55 of of ADP ct-9466 57 56 canine canine PROPN ct-9466 57 57 pyometra pyometra NOUN ct-9466 57 58 with with ADP ct-9466 57 59 pgf2α pgf2α PROPN ct-9466 57 60 is be AUX ct-9466 57 61 86 86 NUM ct-9466 57 62 % % NOUN ct-9466 57 63 ( ( PUNCT ct-9466 57 64 range range NOUN ct-9466 57 65 , , PUNCT ct-9466 57 66 46 46 NUM ct-9466 57 67 100%).4849,54,62 100%).4849,54,62 NUM ct-9466 57 68 - - SYM ct-9466 57 69 70 70 NUM ct-9466 57 70 combining combine VERB ct-9466 57 71 pgf2α pgf2α PROPN ct-9466 57 72 with with ADP ct-9466 57 73 cabergoline cabergoline NOUN ct-9466 57 74 ( ( PUNCT ct-9466 57 75 a a DET ct-9466 57 76 dopamine dopamine NOUN ct-9466 57 77 agonist agonist NOUN ct-9466 57 78 ) ) PUNCT ct-9466 57 79 results result NOUN ct-9466 57 80 in in ADP ct-9466 57 81 resolution resolution NOUN ct-9466 57 82 rates rate NOUN ct-9466 57 83 from from ADP ct-9466 57 84 83 83 NUM ct-9466 57 85 90.5%.66 90.5%.66 NOUN ct-9466 57 86 - - PUNCT ct-9466 57 87 67 67 NUM ct-9466 57 88 resolution resolution NOUN ct-9466 57 89 rate rate NOUN ct-9466 57 90 with with ADP ct-9466 57 91 aglepristone aglepristone ADJ ct-9466 57 92 alone alone ADV ct-9466 57 93 is be AUX ct-9466 57 94 lower low ADJ ct-9466 57 95 ( ( PUNCT ct-9466 57 96 60 60 NUM ct-9466 57 97 % % NOUN ct-9466 57 98 ) ) PUNCT ct-9466 57 99 than than ADP ct-9466 57 100 with with ADP ct-9466 57 101 a a DET ct-9466 57 102 combination combination NOUN ct-9466 57 103 of of ADP ct-9466 57 104 aglepristone aglepristone NOUN ct-9466 57 105 and and CCONJ ct-9466 57 106 cloprostenol cloprostenol NOUN ct-9466 57 107 ( ( PUNCT ct-9466 57 108 84%).16 84%).16 NUM ct-9466 57 109 breeding breeding NOUN ct-9466 57 110 on on ADP ct-9466 57 111 subsequent subsequent ADJ ct-9466 57 112 estrus estrus NOUN ct-9466 57 113 is be AUX ct-9466 57 114 frequently frequently ADV ct-9466 57 115 recommended recommend VERB ct-9466 57 116 after after ADP ct-9466 57 117 medical medical ADJ ct-9466 57 118 management management NOUN ct-9466 57 119 of of ADP ct-9466 57 120 pyometra pyometra NOUN ct-9466 57 121 in in ADP ct-9466 57 122 attempt attempt NOUN ct-9466 57 123 to to PART ct-9466 57 124 avoid avoid VERB ct-9466 57 125 recurrence.43 recurrence.43 NOUN ct-9466 57 126 mean mean VERB ct-9466 57 127 recurrence recurrence NOUN ct-9466 57 128 rate rate NOUN ct-9466 57 129 following follow VERB ct-9466 57 130 medical medical ADJ ct-9466 57 131 management management NOUN ct-9466 57 132 with with ADP ct-9466 57 133 either either DET ct-9466 57 134 treatment treatment NOUN ct-9466 57 135 is be AUX ct-9466 57 136 ~ ~ PUNCT ct-9466 57 137 20 20 NUM ct-9466 57 138 % % NOUN ct-9466 57 139 ( ( PUNCT ct-9466 57 140 range range NOUN ct-9466 57 141 , , PUNCT ct-9466 57 142 0 0 NUM ct-9466 57 143 85%).43,49 85%).43,49 NUM ct-9466 57 144 - - SYM ct-9466 57 145 50,63,71 50,63,71 NUM ct-9466 57 146 it it PRON ct-9466 57 147 is be AUX ct-9466 57 148 important important ADJ ct-9466 57 149 to to PART ct-9466 57 150 mention mention VERB ct-9466 57 151 that that SCONJ ct-9466 57 152 medical medical ADJ ct-9466 57 153 management management NOUN ct-9466 57 154 of of ADP ct-9466 57 155 bitches bitch NOUN ct-9466 57 156 with with ADP ct-9466 57 157 recurrence recurrence NOUN ct-9466 57 158 has have AUX ct-9466 57 159 been be AUX ct-9466 57 160 successful successful ADJ ct-9466 57 161 . . PUNCT ct-9466 58 1 at at ADP ct-9466 58 2 least least ADJ ct-9466 58 3 in in ADP ct-9466 58 4 some some DET ct-9466 58 5 breeds breed NOUN ct-9466 58 6 , , PUNCT ct-9466 58 7 pregnancy pregnancy NOUN ct-9466 58 8 is be AUX ct-9466 58 9 considered consider VERB ct-9466 58 10 to to PART ct-9466 58 11 slightly slightly ADV ct-9466 58 12 reduce reduce VERB ct-9466 58 13 the the DET ct-9466 58 14 risk risk NOUN ct-9466 58 15 for for ADP ct-9466 58 16 pyometra pyometra ADJ ct-9466 58 17 recurrence recurrence NOUN ct-9466 58 18 , , PUNCT ct-9466 58 19 which which PRON ct-9466 58 20 points point VERB ct-9466 58 21 to to ADP ct-9466 58 22 genetic genetic ADJ ct-9466 58 23 differences difference NOUN ct-9466 58 24 in in ADP ct-9466 58 25 protective protective ADJ ct-9466 58 26 factors.10,39 factors.10,39 NOUN ct-9466 58 27 however however ADV ct-9466 58 28 , , PUNCT ct-9466 58 29 pregnancy pregnancy NOUN ct-9466 58 30 is be AUX ct-9466 58 31 not not PART ct-9466 58 32 completely completely ADV ct-9466 58 33 protective protective ADJ ct-9466 58 34 , , PUNCT ct-9466 58 35 and and CCONJ ct-9466 58 36 developing develop VERB ct-9466 58 37 pyometra pyometra NOUN ct-9466 58 38 during during ADP ct-9466 58 39 pregnancy pregnancy NOUN ct-9466 58 40 has have AUX ct-9466 58 41 been be AUX ct-9466 58 42 reported report VERB ct-9466 58 43 in in ADP ct-9466 58 44 several several ADJ ct-9466 58 45 cases.15 cases.15 PROPN ct-9466 58 46 644clinical 644clinical PROPN ct-9466 58 47 theriogenology theriogenology NOUN ct-9466 58 48 • • NOUN ct-9466 58 49 volume volume NOUN ct-9466 58 50 11 11 NUM ct-9466 58 51 , , PUNCT ct-9466 58 52 number number NOUN ct-9466 58 53 4 4 NUM ct-9466 58 54 • • NOUN ct-9466 58 55 december december PROPN ct-9466 58 56 2019 2019 NUM ct-9466 58 57     SPACE ct-9466 58 58 table table NOUN ct-9466 58 59 3 3 NUM ct-9466 58 60 . . PUNCT ct-9466 58 61 medical medical ADJ ct-9466 58 62 management management NOUN ct-9466 58 63 of of ADP ct-9466 58 64 canine canine NOUN ct-9466 58 65 pyometra pyometra NOUN ct-9466 58 66 using use VERB ct-9466 58 67 prostaglandin prostaglandin PROPN ct-9466 58 68 f2α f2α PROPN ct-9466 58 69 ( ( PUNCT ct-9466 58 70 pgf2α pgf2α ADJ ct-9466 58 71 ) ) PUNCT ct-9466 58 72 or or CCONJ ct-9466 58 73 aglepristone aglepristone ADJ ct-9466 58 74 . . PUNCT ct-9466 59 1 mechanism mechanism NOUN ct-9466 59 2 of of ADP ct-9466 59 3 action action NOUN ct-9466 59 4 protocol protocol NOUN ct-9466 59 5 efficacy efficacy NOUN ct-9466 59 6 adverse adverse ADJ ct-9466 59 7 effects effect NOUN ct-9466 59 8 pgf2α pgf2α PROPN ct-9466 59 9 pgf2α pgf2α PROPN ct-9466 59 10 is be AUX ct-9466 59 11 both both CCONJ ct-9466 59 12 luteolytic luteolytic ADJ ct-9466 59 13 and and CCONJ ct-9466 59 14 uterotonic uterotonic ADJ ct-9466 59 15 . . PUNCT ct-9466 60 1 efficacy efficacy NOUN ct-9466 60 2 of of ADP ct-9466 60 3 treatment treatment NOUN ct-9466 60 4 is be AUX ct-9466 60 5 correlated correlate VERB ct-9466 60 6 to to ADP ct-9466 60 7 repeated repeat VERB ct-9466 60 8 administration administration NOUN ct-9466 60 9 rather rather ADV ct-9466 60 10 than than ADP ct-9466 60 11 overall overall ADJ ct-9466 60 12 total total ADJ ct-9466 60 13 dose dose NOUN ct-9466 60 14 administered administer VERB ct-9466 60 15 . . PUNCT ct-9466 61 1 comparison comparison NOUN ct-9466 61 2 of of ADP ct-9466 61 3 uterotonic uterotonic ADJ ct-9466 61 4 effect effect NOUN ct-9466 61 5 in in ADP ct-9466 61 6 diestrus diestrus NOUN ct-9466 61 7 bitches bitch NOUN ct-9466 61 8 of of ADP ct-9466 61 9 pgf2α pgf2α PROPN ct-9466 61 10 at at ADP ct-9466 61 11 a a DET ct-9466 61 12 dosage dosage NOUN ct-9466 61 13 of of ADP ct-9466 61 14 250 250 NUM ct-9466 61 15 µg µg NOUN ct-9466 61 16 / / SYM ct-9466 61 17 kg kg NOUN ct-9466 61 18 compared compare VERB ct-9466 61 19 to to ADP ct-9466 61 20 50 50 NUM ct-9466 61 21 µg µg NOUN ct-9466 61 22 / / SYM ct-9466 61 23 kg kg NOUN ct-9466 61 24 resulted result VERB ct-9466 61 25 in in ADP ct-9466 61 26 uterine uterine ADJ ct-9466 61 27 contractility contractility NOUN ct-9466 61 28 for for ADP ct-9466 61 29 32 32 NUM ct-9466 61 30 and and CCONJ ct-9466 61 31 23 23 NUM ct-9466 61 32 minutes minute NOUN ct-9466 61 33 , , PUNCT ct-9466 61 34 respectively.51,75 respectively.51,75 NOUN ct-9466 61 35 pgf2α pgf2α PROPN ct-9466 61 36 is be AUX ct-9466 61 37 most most ADV ct-9466 61 38 effective effective ADJ ct-9466 61 39 when when SCONJ ct-9466 61 40 administered administer VERB ct-9466 61 41 in in ADP ct-9466 61 42 repeated repeat VERB ct-9466 61 43 low low ADJ ct-9466 61 44 doses dose NOUN ct-9466 61 45 for for ADP ct-9466 61 46 8 8 NUM ct-9466 61 47 10 10 NUM ct-9466 61 48 days day NOUN ct-9466 61 49 . . PUNCT ct-9466 62 1 administer administer VERB ct-9466 62 2 natural natural ADJ ct-9466 62 3 pgf2α pgf2α PROPN ct-9466 62 4 at at ADP ct-9466 62 5 a a DET ct-9466 62 6 dosage dosage NOUN ct-9466 62 7 of of ADP ct-9466 62 8 10 10 NUM ct-9466 62 9 50 50 NUM ct-9466 62 10 µg µg NOUN ct-9466 62 11 / / SYM ct-9466 62 12 kg kg NOUN ct-9466 62 13 sc sc NOUN ct-9466 62 14 every every DET ct-9466 62 15 4 4 NUM ct-9466 62 16 6 6 NUM ct-9466 62 17 hours.7,45,68 hours.7,45,68 PROPN ct-9466 62 18 - - PUNCT ct-9466 62 19 70 70 NUM ct-9466 62 20 administer administer NOUN ct-9466 62 21 cloprostenol cloprostenol NOUN ct-9466 62 22 at at ADP ct-9466 62 23 a a DET ct-9466 62 24 dosage dosage NOUN ct-9466 62 25 of of ADP ct-9466 62 26 1 1 NUM ct-9466 62 27 3 3 NUM ct-9466 62 28 µg µg NOUN ct-9466 62 29 / / SYM ct-9466 62 30 kg kg NOUN ct-9466 62 31 sc sc NOUN ct-9466 62 32 every every DET ct-9466 62 33 12 12 NUM ct-9466 62 34 24 24 NUM ct-9466 62 35 hours.62,74 hours.62,74 NOUN ct-9466 62 36 following follow VERB ct-9466 62 37 first first ADJ ct-9466 62 38 treatment treatment NOUN ct-9466 62 39 , , PUNCT ct-9466 62 40 copious copious ADJ ct-9466 62 41 discharge discharge NOUN ct-9466 62 42 will will AUX ct-9466 62 43 be be AUX ct-9466 62 44 observed observe VERB ct-9466 62 45 coming come VERB ct-9466 62 46 from from ADP ct-9466 62 47 vulva vulva NOUN ct-9466 62 48 for for ADP ct-9466 62 49 first first ADJ ct-9466 62 50 48 48 NUM ct-9466 62 51 hours hour NOUN ct-9466 62 52 and and CCONJ ct-9466 62 53 then then ADV ct-9466 62 54 will will AUX ct-9466 62 55 start start VERB ct-9466 62 56 to to PART ct-9466 62 57 decrease decrease VERB ct-9466 62 58 . . PUNCT ct-9466 63 1 hemorrhagic hemorrhagic ADJ ct-9466 63 2 discharge discharge NOUN ct-9466 63 3 may may AUX ct-9466 63 4 be be AUX ct-9466 63 5 observed observe VERB ct-9466 63 6 4 4 NUM ct-9466 63 7 5 5 NUM ct-9466 63 8 days day NOUN ct-9466 63 9 into into ADP ct-9466 63 10 treatment treatment NOUN ct-9466 63 11 . . PUNCT ct-9466 64 1 evacuation evacuation NOUN ct-9466 64 2 of of ADP ct-9466 64 3 uterine uterine ADJ ct-9466 64 4 contents content NOUN ct-9466 64 5 greatly greatly ADV ct-9466 64 6 improves improve VERB ct-9466 64 7 bitch bitch NOUN ct-9466 64 8 ’s ’s PART ct-9466 64 9 physical physical ADJ ct-9466 64 10 condition condition NOUN ct-9466 64 11 . . PUNCT ct-9466 65 1 treatment treatment NOUN ct-9466 65 2 efficacy efficacy NOUN ct-9466 65 3 is be AUX ct-9466 65 4 confirmed confirm VERB ct-9466 65 5 by by ADP ct-9466 65 6 ultrasonographic ultrasonographic ADJ ct-9466 65 7 clearance clearance NOUN ct-9466 65 8 of of ADP ct-9466 65 9 uterine uterine ADJ ct-9466 65 10 contents content NOUN ct-9466 65 11 10 10 NUM ct-9466 65 12 14 14 NUM ct-9466 65 13 days day NOUN ct-9466 65 14 after after ADP ct-9466 65 15 first first ADJ ct-9466 65 16 treatment treatment NOUN ct-9466 65 17 . . PUNCT ct-9466 66 1 adverse adverse ADJ ct-9466 66 2 effects effect NOUN ct-9466 66 3 are be AUX ct-9466 66 4 dose dose NOUN ct-9466 66 5 - - PUNCT ct-9466 66 6 dependent dependent ADJ ct-9466 66 7 and and CCONJ ct-9466 66 8 develop develop VERB ct-9466 66 9 within within ADP ct-9466 66 10 minutes minute NOUN ct-9466 66 11 and and CCONJ ct-9466 66 12 last last ADJ ct-9466 66 13 for for SCONJ ct-9466 66 14 ~ ~ SYM ct-9466 66 15 1 1 NUM ct-9466 66 16 hour.62 hour.62 NOUN ct-9466 66 17 adverse adverse ADJ ct-9466 66 18 effects effect NOUN ct-9466 66 19 include include VERB ct-9466 66 20 hypothermia hypothermia NOUN ct-9466 66 21 and and CCONJ ct-9466 66 22 shivering shiver VERB ct-9466 66 23 , , PUNCT ct-9466 66 24 increased increase VERB ct-9466 66 25 frequency frequency NOUN ct-9466 66 26 of of ADP ct-9466 66 27 defecation defecation NOUN ct-9466 66 28 ( ( PUNCT ct-9466 66 29 ± ± NOUN ct-9466 66 30 diarrhea diarrhea PROPN ct-9466 66 31 ) ) PUNCT ct-9466 66 32 , , PUNCT ct-9466 66 33 hypersalivation hypersalivation NOUN ct-9466 66 34 and and CCONJ ct-9466 66 35 vomiting vomiting NOUN ct-9466 66 36 . . PUNCT ct-9466 67 1 administer administer NOUN ct-9466 67 2 atropine atropine NOUN ct-9466 67 3 ( ( PUNCT ct-9466 67 4 25 25 NUM ct-9466 67 5 µg µg NOUN ct-9466 67 6 / / SYM ct-9466 67 7 kg kg PROPN ct-9466 67 8 sc sc PROPN ct-9466 67 9 ) ) PUNCT ct-9466 67 10 15 15 NUM ct-9466 67 11 minutes minute NOUN ct-9466 67 12 before before ADP ct-9466 67 13 pgf2α pgf2α PROPN ct-9466 67 14 and and CCONJ ct-9466 67 15 walk walk VERB ct-9466 67 16 bitch bitch NOUN ct-9466 67 17 for for ADP ct-9466 67 18 15 15 NUM ct-9466 67 19 20 20 NUM ct-9466 67 20 minutes minute NOUN ct-9466 67 21 after after SCONJ ct-9466 67 22 administration administration NOUN ct-9466 67 23 to to PART ct-9466 67 24 lessen lessen VERB ct-9466 67 25 symptoms symptom NOUN ct-9466 67 26 . . PUNCT ct-9466 68 1 brachycephalic brachycephalic ADJ ct-9466 68 2 breeds breed NOUN ct-9466 68 3 may may AUX ct-9466 68 4 also also ADV ct-9466 68 5 be be AUX ct-9466 68 6 predisposed predispose VERB ct-9466 68 7 to to PART ct-9466 68 8 bronchospasm.45,52 bronchospasm.45,52 VERB ct-9466 68 9 dosage dosage NOUN ct-9466 68 10 calculations calculation NOUN ct-9466 68 11 must must AUX ct-9466 68 12 be be AUX ct-9466 68 13 done do VERB ct-9466 68 14 correctly correctly ADV ct-9466 68 15 to to PART ct-9466 68 16 prevent prevent VERB ct-9466 68 17 serious serious ADJ ct-9466 68 18 adverse adverse ADJ ct-9466 68 19 effects effect NOUN ct-9466 68 20 , , PUNCT ct-9466 68 21 including include VERB ct-9466 68 22 hypovolemic hypovolemic ADJ ct-9466 68 23 shock shock NOUN ct-9466 68 24 , , PUNCT ct-9466 68 25 ventricular ventricular ADJ ct-9466 68 26 tachycardia tachycardia NOUN ct-9466 68 27 and and CCONJ ct-9466 68 28 death.43 death.43 PROPN ct-9466 68 29 aglepristone aglepristone PROPN ct-9466 68 30 aglepristone aglepristone NOUN ct-9466 68 31 is be AUX ct-9466 68 32 a a DET ct-9466 68 33 progesterone progesterone NOUN ct-9466 68 34 receptor receptor NOUN ct-9466 68 35 antagonist antagonist NOUN ct-9466 68 36 that that PRON ct-9466 68 37 competitively competitively ADV ct-9466 68 38 binds bind VERB ct-9466 68 39 progesterone progesterone NOUN ct-9466 68 40 receptors receptor NOUN ct-9466 68 41 and and CCONJ ct-9466 68 42 decreases decrease VERB ct-9466 68 43 intrauterine intrauterine ADJ ct-9466 68 44 progesterone progesterone NOUN ct-9466 68 45 concentration concentration NOUN ct-9466 68 46 . . PUNCT ct-9466 69 1 aglepristone aglepristone NOUN ct-9466 69 2 does do AUX ct-9466 69 3 not not PART ct-9466 69 4 have have VERB ct-9466 69 5 direct direct ADJ ct-9466 69 6 uterotonic uterotonic ADJ ct-9466 69 7 activity activity NOUN ct-9466 69 8 . . PUNCT ct-9466 70 1 administer administer NOUN ct-9466 70 2 aglepristone aglepristone ADV ct-9466 70 3 at at ADP ct-9466 70 4 a a DET ct-9466 70 5 dosage dosage NOUN ct-9466 70 6 of of ADP ct-9466 70 7 10 10 NUM ct-9466 70 8 mg mg NUM ct-9466 70 9 / / SYM ct-9466 70 10 kg kg PROPN ct-9466 70 11 sc sc PROPN ct-9466 70 12 on on ADP ct-9466 70 13 days day NOUN ct-9466 70 14 1 1 NUM ct-9466 70 15 , , PUNCT ct-9466 70 16 3 3 NUM ct-9466 70 17 , , PUNCT ct-9466 70 18 6 6 NUM ct-9466 70 19 and and CCONJ ct-9466 70 20 9 9 NUM ct-9466 70 21 of of ADP ct-9466 70 22 treatment.63 treatment.63 PROPN ct-9466 70 23 if if SCONJ ct-9466 70 24 uterine uterine ADJ ct-9466 70 25 contents content NOUN ct-9466 70 26 are be AUX ct-9466 70 27 still still ADV ct-9466 70 28 visible visible ADJ ct-9466 70 29 on on ADP ct-9466 70 30 day day NOUN ct-9466 70 31 15 15 NUM ct-9466 70 32 , , PUNCT ct-9466 70 33 administer administer VERB ct-9466 70 34 another another DET ct-9466 70 35 injection injection NOUN ct-9466 70 36 on on ADP ct-9466 70 37 day day NOUN ct-9466 70 38 15 15 NUM ct-9466 70 39 and and CCONJ ct-9466 70 40 on on ADP ct-9466 70 41 day day NOUN ct-9466 70 42 30 30 NUM ct-9466 70 43 . . PUNCT ct-9466 71 1 results result NOUN ct-9466 71 2 can can AUX ct-9466 71 3 be be AUX ct-9466 71 4 improved improve VERB ct-9466 71 5 by by ADP ct-9466 71 6 giving give VERB ct-9466 71 7 cloprostenol cloprostenol NOUN ct-9466 71 8 ( ( PUNCT ct-9466 71 9 1 1 NUM ct-9466 71 10 µg µg NOUN ct-9466 71 11 / / SYM ct-9466 71 12 kg kg PROPN ct-9466 71 13 sc sc PROPN ct-9466 71 14 ) ) PUNCT ct-9466 71 15 from from ADP ct-9466 71 16 days day NOUN ct-9466 71 17 3 3 NUM ct-9466 71 18 7.16 7.16 NUM ct-9466 71 19 when when SCONJ ct-9466 71 20 a a DET ct-9466 71 21 combination combination NOUN ct-9466 71 22 of of ADP ct-9466 71 23 aglepristone aglepristone NOUN ct-9466 71 24 and and CCONJ ct-9466 71 25 cloprostenol cloprostenol NOUN ct-9466 71 26 is be AUX ct-9466 71 27 administered administer VERB ct-9466 71 28 , , PUNCT ct-9466 71 29 there there PRON ct-9466 71 30 was be VERB ct-9466 71 31 no no DET ct-9466 71 32 significant significant ADJ ct-9466 71 33 difference difference NOUN ct-9466 71 34 in in ADP ct-9466 71 35 success success NOUN ct-9466 71 36 rates rate NOUN ct-9466 71 37 between between ADP ct-9466 71 38 bitches bitch NOUN ct-9466 71 39 with with ADP ct-9466 71 40 open open ADJ ct-9466 71 41 versus versus ADP ct-9466 71 42 closed closed ADJ ct-9466 71 43 pyometra.16 pyometra.16 PROPN ct-9466 71 44 adverse adverse ADJ ct-9466 71 45 effects effect NOUN ct-9466 71 46 have have AUX ct-9466 71 47 not not PART ct-9466 71 48 been be AUX ct-9466 71 49 reported report VERB ct-9466 71 50 when when SCONJ ct-9466 71 51 using use VERB ct-9466 71 52 aglepristone aglepristone NOUN ct-9466 71 53 alone alone ADV ct-9466 71 54 . . PUNCT ct-9466 72 1 vomiting vomiting NOUN ct-9466 72 2 has have AUX ct-9466 72 3 been be AUX ct-9466 72 4 reported report VERB ct-9466 72 5 when when SCONJ ct-9466 72 6 used use VERB ct-9466 72 7 in in ADP ct-9466 72 8 combination combination NOUN ct-9466 72 9 with with ADP ct-9466 72 10 cloprostenol.16 cloprostenol.16 PROPN ct-9466 72 11 645 645 NUM ct-9466 72 12 clinical clinical ADJ ct-9466 72 13 theriogenology theriogenology NOUN ct-9466 72 14 • • NOUN ct-9466 72 15 volume volume NOUN ct-9466 72 16 11 11 NUM ct-9466 72 17 , , PUNCT ct-9466 72 18 number number NOUN ct-9466 72 19 4 4 NUM ct-9466 72 20 • • NOUN ct-9466 72 21 december december PROPN ct-9466 72 22 2019 2019 NUM ct-9466 72 23     SPACE ct-9466 72 24 references reference NOUN ct-9466 72 25 1 1 NUM ct-9466 72 26 . . X ct-9466 72 27 wallace wallace PROPN ct-9466 72 28 gb gb PROPN ct-9466 72 29 , , PUNCT ct-9466 72 30 casal casal NOUN ct-9466 72 31 ml ml NOUN ct-9466 72 32 : : PUNCT ct-9466 72 33 a a DET ct-9466 72 34 review review NOUN ct-9466 72 35 of of ADP ct-9466 72 36 pyometra pyometra NOUN ct-9466 72 37 in in ADP ct-9466 72 38 small small ADJ ct-9466 72 39 animal animal NOUN ct-9466 72 40 medicine medicine NOUN ct-9466 72 41 : : PUNCT ct-9466 72 42 incidence incidence NOUN ct-9466 72 43 , , PUNCT ct-9466 72 44 pathophysiology pathophysiology NOUN ct-9466 72 45 , , PUNCT ct-9466 72 46 clinical clinical ADJ ct-9466 72 47 diagnosis diagnosis NOUN ct-9466 72 48 , , PUNCT ct-9466 72 49 and and CCONJ ct-9466 72 50 medical medical ADJ ct-9466 72 51 management management NOUN ct-9466 72 52 . . PUNCT ct-9466 73 1 clinical clinical ADJ ct-9466 73 2 theriogenology theriogenology NOUN ct-9466 73 3 2018;10:435 2018;10:435 PROPN ct-9466 73 4 - - SYM ct-9466 73 5 452 452 NUM ct-9466 73 6 2 2 NUM ct-9466 73 7 . . PUNCT ct-9466 73 8 jitpean jitpean PROPN ct-9466 73 9 s s PROPN ct-9466 73 10 , , PUNCT ct-9466 73 11 hagman hagman PROPN ct-9466 73 12 r r PROPN ct-9466 73 13 , , PUNCT ct-9466 73 14 strom strom PROPN ct-9466 73 15 holst holst PROPN ct-9466 73 16 b b X ct-9466 73 17 , , PUNCT ct-9466 73 18 et et PROPN ct-9466 73 19 al al PROPN ct-9466 73 20 : : PUNCT ct-9466 73 21 breed breed NOUN ct-9466 73 22 variations variation NOUN ct-9466 73 23 in in ADP ct-9466 73 24 the the DET ct-9466 73 25 incidence incidence NOUN ct-9466 73 26 of of ADP ct-9466 73 27 pyometra pyometra ADJ ct-9466 73 28 and and CCONJ ct-9466 73 29 mammary mammary ADJ ct-9466 73 30 tumours tumour NOUN ct-9466 73 31 in in ADP ct-9466 73 32 swedish swedish ADJ ct-9466 73 33 dogs dog NOUN ct-9466 73 34 . . PUNCT ct-9466 74 1 reprod reprod PROPN ct-9466 74 2 domestic domestic ADJ ct-9466 74 3 anim anim NOUN ct-9466 74 4 2012;47 2012;47 NUM ct-9466 74 5 suppl suppl PROPN ct-9466 75 1 6:347 6:347 PROPN ct-9466 75 2 - - SYM ct-9466 75 3 350 350 NUM ct-9466 75 4 . . PUNCT ct-9466 76 1 3 3 X ct-9466 76 2 . . X ct-9466 76 3 jitpean jitpean PROPN ct-9466 76 4 s s PROPN ct-9466 76 5 , , PUNCT ct-9466 76 6 ambrosen ambrosen VERB ct-9466 76 7 a a DET ct-9466 76 8 , , PUNCT ct-9466 76 9 emanuelson emanuelson NOUN ct-9466 76 10 u u NOUN ct-9466 76 11 , , PUNCT ct-9466 76 12 et et PROPN ct-9466 76 13 al al PROPN ct-9466 76 14 : : PUNCT ct-9466 76 15 closed closed ADJ ct-9466 76 16 cervix cervix NOUN ct-9466 76 17 is be AUX ct-9466 76 18 associated associate VERB ct-9466 76 19 with with ADP ct-9466 76 20 more more ADV ct-9466 76 21 severe severe ADJ ct-9466 76 22 illness illness NOUN ct-9466 76 23 in in ADP ct-9466 76 24 dogs dog NOUN ct-9466 76 25 with with ADP ct-9466 76 26 pyometra pyometra NOUN ct-9466 76 27 . . PUNCT ct-9466 77 1 bmc bmc PROPN ct-9466 77 2 vet vet NOUN ct-9466 77 3 res re NOUN ct-9466 77 4 2017;13:11 2017;13:11 NUM ct-9466 77 5 . . PUNCT ct-9466 78 1 doi doi NOUN ct-9466 78 2 : : PUNCT ct-9466 78 3 10.1186 10.1186 NUM ct-9466 78 4 / / SYM ct-9466 78 5 s12917 s12917 NOUN ct-9466 78 6 - - PUNCT ct-9466 78 7 016 016 NUM ct-9466 78 8 - - PUNCT ct-9466 78 9 0924 0924 NUM ct-9466 78 10 - - SYM ct-9466 78 11 0 0 NUM ct-9466 78 12 . . NOUN ct-9466 79 1 4 4 NUM ct-9466 79 2 . . X ct-9466 79 3 jitpean jitpean PROPN ct-9466 79 4 s s PROPN ct-9466 79 5 , , PUNCT ct-9466 79 6 pettersson pettersson PROPN ct-9466 79 7 a a NOUN ct-9466 79 8 , , PUNCT ct-9466 79 9 höglund höglund ADJ ct-9466 79 10 ov ov PROPN ct-9466 79 11 , , PUNCT ct-9466 79 12 et et PROPN ct-9466 79 13 al al PROPN ct-9466 79 14 : : PUNCT ct-9466 79 15 increased increase VERB ct-9466 79 16 concentrations concentration NOUN ct-9466 79 17 of of ADP ct-9466 79 18 serum serum NOUN ct-9466 79 19 amyloid amyloid NOUN ct-9466 79 20 a a PRON ct-9466 79 21 in in ADP ct-9466 79 22 dogs dog NOUN ct-9466 79 23 with with ADP ct-9466 79 24 sepsis sepsis NOUN ct-9466 79 25 caused cause VERB ct-9466 79 26 by by ADP ct-9466 79 27 pyometra pyometra NOUN ct-9466 79 28 . . PUNCT ct-9466 80 1 bmc bmc PROPN ct-9466 80 2 vet vet NOUN ct-9466 80 3 res re NOUN ct-9466 80 4 2014;10:273 2014;10:273 NUM ct-9466 80 5 . . NOUN ct-9466 81 1 5 5 NUM ct-9466 81 2 . . X ct-9466 81 3 jitpean jitpean PROPN ct-9466 81 4 s s PROPN ct-9466 81 5 , , PUNCT ct-9466 81 6 strom strom PROPN ct-9466 81 7 - - PUNCT ct-9466 81 8 holst holst PROPN ct-9466 81 9 b b NOUN ct-9466 81 10 , , PUNCT ct-9466 81 11 emanuelson emanuelson NOUN ct-9466 81 12 u u NOUN ct-9466 81 13 , , PUNCT ct-9466 81 14 et et PROPN ct-9466 81 15 al al PROPN ct-9466 81 16 : : PUNCT ct-9466 81 17 outcome outcome NOUN ct-9466 81 18 of of ADP ct-9466 81 19 pyometra pyometra NOUN ct-9466 81 20 in in ADP ct-9466 81 21 female female ADJ ct-9466 81 22 dogs dog NOUN ct-9466 81 23 and and CCONJ ct-9466 81 24 predictors predictor NOUN ct-9466 81 25 of of ADP ct-9466 81 26 peritonitis peritonitis NOUN ct-9466 81 27 and and CCONJ ct-9466 81 28 prolonged prolong VERB ct-9466 81 29 postoperative postoperative ADJ ct-9466 81 30 hospitalization hospitalization NOUN ct-9466 81 31 in in ADP ct-9466 81 32 surgically surgically ADV ct-9466 81 33 treated treat VERB ct-9466 81 34 cases case NOUN ct-9466 81 35 . . PUNCT ct-9466 82 1 bmc bmc ADJ ct-9466 82 2 vet vet NOUN ct-9466 82 3 res re NOUN ct-9466 82 4 2014;10:6 2014;10:6 NOUN ct-9466 82 5 . . PUNCT ct-9466 83 1 6 6 NUM ct-9466 83 2 . . X ct-9466 83 3 pretzer pretzer NOUN ct-9466 83 4 sd sd PROPN ct-9466 83 5 : : PUNCT ct-9466 83 6 clinical clinical ADJ ct-9466 83 7 presentation presentation NOUN ct-9466 83 8 of of ADP ct-9466 83 9 canine canine NOUN ct-9466 83 10 pyometra pyometra NOUN ct-9466 83 11 and and CCONJ ct-9466 83 12 mucometra mucometra PROPN ct-9466 83 13 : : PUNCT ct-9466 83 14 a a DET ct-9466 83 15 review review NOUN ct-9466 83 16 . . PUNCT ct-9466 84 1 theriogenology theriogenology NOUN ct-9466 84 2 2008;70:359 2008;70:359 PROPN ct-9466 84 3 - - SYM ct-9466 84 4 363 363 NUM ct-9466 84 5 . . PUNCT ct-9466 85 1 7 7 NUM ct-9466 85 2 . . X ct-9466 85 3 verstegen verstegen PROPN ct-9466 85 4 j j PROPN ct-9466 85 5 , , PUNCT ct-9466 85 6 dhaliwal dhaliwal PROPN ct-9466 85 7 g g PROPN ct-9466 85 8 , , PUNCT ct-9466 85 9 verstegen verstegen NOUN ct-9466 85 10 - - PUNCT ct-9466 85 11 onclin onclin NOUN ct-9466 85 12 k k NOUN ct-9466 85 13 : : PUNCT ct-9466 85 14 mucometra mucometra ADJ ct-9466 85 15 , , PUNCT ct-9466 85 16 cystic cystic ADJ ct-9466 85 17 endometrial endometrial ADJ ct-9466 85 18 hyperplasia hyperplasia NOUN ct-9466 85 19 , , PUNCT ct-9466 85 20 and and CCONJ ct-9466 85 21 pyometra pyometra NOUN ct-9466 85 22 in in ADP ct-9466 85 23 the the DET ct-9466 85 24 bitch bitch NOUN ct-9466 85 25 : : PUNCT ct-9466 85 26 advances advance NOUN ct-9466 85 27 in in ADP ct-9466 85 28 treatment treatment NOUN ct-9466 85 29 and and CCONJ ct-9466 85 30 assessment assessment NOUN ct-9466 85 31 of of ADP ct-9466 85 32 future future ADJ ct-9466 85 33 reproductive reproductive ADJ ct-9466 85 34 success success NOUN ct-9466 85 35 . . PUNCT ct-9466 86 1 theriogenology theriogenology NOUN ct-9466 86 2 2008;70:364 2008;70:364 NOUN ct-9466 86 3 - - SYM ct-9466 86 4 374 374 NUM ct-9466 86 5 . . NOUN ct-9466 86 6 8 8 NUM ct-9466 86 7 . . X ct-9466 86 8 krekeler krekeler PROPN ct-9466 86 9 n n CCONJ ct-9466 86 10 , , PUNCT ct-9466 86 11 marenda marenda ADV ct-9466 86 12 ms ms PROPN ct-9466 86 13 , , PUNCT ct-9466 86 14 browning brown VERB ct-9466 86 15 gf gf NOUN ct-9466 86 16 , , PUNCT ct-9466 86 17 et et PROPN ct-9466 86 18 al al PROPN ct-9466 86 19 : : PUNCT ct-9466 86 20 uropathogenic uropathogenic ADJ ct-9466 86 21 virulence virulence NOUN ct-9466 86 22 factor factor NOUN ct-9466 86 23 fimh fimh NOUN ct-9466 86 24 facilitates facilitate VERB ct-9466 86 25 binding bind VERB ct-9466 86 26 of of ADP ct-9466 86 27 uteropathogenic uteropathogenic ADJ ct-9466 86 28 escherichia escherichia NOUN ct-9466 86 29 coli coli NOUN ct-9466 86 30 to to PART ct-9466 86 31 canine canine VERB ct-9466 86 32 endometrium endometrium NOUN ct-9466 86 33 . . PUNCT ct-9466 87 1 comp comp PROPN ct-9466 87 2 immunol immunol PROPN ct-9466 87 3 microbiol microbiol PROPN ct-9466 87 4 infect infect VERB ct-9466 87 5 dis dis PROPN ct-9466 87 6 2012;35:461 2012;35:461 PROPN ct-9466 87 7 - - PUNCT ct-9466 87 8 467 467 NUM ct-9466 87 9 . . NOUN ct-9466 87 10 9 9 NUM ct-9466 87 11 . . X ct-9466 88 1 dow dow PROPN ct-9466 88 2 c c PROPN ct-9466 88 3 : : PUNCT ct-9466 88 4 the the DET ct-9466 88 5 cystic cystic ADJ ct-9466 88 6 hyperplasia hyperplasia NOUN ct-9466 88 7 - - PUNCT ct-9466 88 8 pyometra pyometra NOUN ct-9466 88 9 complex complex NOUN ct-9466 88 10 in in ADP ct-9466 88 11 the the DET ct-9466 88 12 bitch bitch NOUN ct-9466 88 13 . . PUNCT ct-9466 89 1 j j PROPN ct-9466 89 2 comp comp PROPN ct-9466 89 3 pathol pathol PROPN ct-9466 89 4 1959;69:237 1959;69:237 PROPN ct-9466 89 5 - - PUNCT ct-9466 89 6 251 251 NUM ct-9466 89 7 . . PUNCT ct-9466 90 1 10 10 NUM ct-9466 90 2 . . PUNCT ct-9466 91 1 niskanen niskanen PROPN ct-9466 91 2 m m PROPN ct-9466 91 3 , , PUNCT ct-9466 91 4 thrusfield thrusfield VERB ct-9466 91 5 mv mv NOUN ct-9466 91 6 : : PUNCT ct-9466 91 7 associations association NOUN ct-9466 91 8 between between ADP ct-9466 91 9 age age NOUN ct-9466 91 10 , , PUNCT ct-9466 91 11 parity parity NOUN ct-9466 91 12 , , PUNCT ct-9466 91 13 hormonal hormonal ADJ ct-9466 91 14 therapy therapy NOUN ct-9466 91 15 and and CCONJ ct-9466 91 16 breed breed NOUN ct-9466 91 17 , , PUNCT ct-9466 91 18 and and CCONJ ct-9466 91 19 pyometra pyometra NOUN ct-9466 91 20 in in ADP ct-9466 91 21 finnish finnish ADJ ct-9466 91 22 dogs dog NOUN ct-9466 91 23 . . PUNCT ct-9466 92 1 vet vet NOUN ct-9466 92 2 rec rec X ct-9466 92 3 1998;143:493 1998;143:493 NUM ct-9466 92 4 - - SYM ct-9466 92 5 498 498 NUM ct-9466 92 6 . . PUNCT ct-9466 93 1 11 11 NUM ct-9466 93 2 . . PUNCT ct-9466 94 1 chen chen PROPN ct-9466 94 2 ymm ymm PROPN ct-9466 94 3 , , PUNCT ct-9466 94 4 lee lee PROPN ct-9466 94 5 cs cs PROPN ct-9466 94 6 , , PUNCT ct-9466 94 7 wright wright PROPN ct-9466 94 8 pj pj PROPN ct-9466 94 9 : : PUNCT ct-9466 94 10 the the DET ct-9466 94 11 roles role NOUN ct-9466 94 12 of of ADP ct-9466 94 13 progestogen progestogen NOUN ct-9466 94 14 and and CCONJ ct-9466 94 15 uterine uterine ADJ ct-9466 94 16 irritant irritant ADJ ct-9466 94 17 in in ADP ct-9466 94 18 the the DET ct-9466 94 19 maintenance maintenance NOUN ct-9466 94 20 of of ADP ct-9466 94 21 cystic cystic ADJ ct-9466 94 22 endometrial endometrial ADJ ct-9466 94 23 hyperplasia hyperplasia NOUN ct-9466 94 24 in in ADP ct-9466 94 25 the the DET ct-9466 94 26 canine canine NOUN ct-9466 94 27 uterus uterus NOUN ct-9466 94 28 . . PUNCT ct-9466 95 1 theriogenology theriogenology NOUN ct-9466 95 2 2006;66:1537 2006;66:1537 PROPN ct-9466 95 3 - - SYM ct-9466 95 4 1544 1544 NUM ct-9466 95 5 . . PUNCT ct-9466 96 1 12 12 NUM ct-9466 96 2 . . PUNCT ct-9466 97 1 teunissen teunissen NOUN ct-9466 97 2 ghb ghb PROPN ct-9466 97 3 : : PUNCT ct-9466 97 4 the the DET ct-9466 97 5 development development NOUN ct-9466 97 6 of of ADP ct-9466 97 7 endometritis endometritis NOUN ct-9466 97 8 in in ADP ct-9466 97 9 the the DET ct-9466 97 10 dog dog NOUN ct-9466 97 11 and and CCONJ ct-9466 97 12 the the DET ct-9466 97 13 effect effect NOUN ct-9466 97 14 of of ADP ct-9466 97 15 oestradiol oestradiol NOUN ct-9466 97 16 and and CCONJ ct-9466 97 17 progesterone progesterone NOUN ct-9466 97 18 on on ADP ct-9466 97 19 the the DET ct-9466 97 20 uterus uterus NOUN ct-9466 97 21 . . PUNCT ct-9466 98 1 acta acta PROPN ct-9466 98 2 endocrinol endocrinol PROPN ct-9466 98 3 ( ( PUNCT ct-9466 98 4 copenhagen copenhagen PROPN ct-9466 98 5 ) ) PUNCT ct-9466 98 6 1952;9:407 1952;9:407 NUM ct-9466 98 7 - - SYM ct-9466 98 8 420 420 NUM ct-9466 98 9 . . PUNCT ct-9466 98 10 13 13 NUM ct-9466 98 11 . . PUNCT ct-9466 98 12 reusche reusche PROPN ct-9466 98 13 n n CCONJ ct-9466 98 14 , , PUNCT ct-9466 98 15 beineke beineke VERB ct-9466 98 16 a a PRON ct-9466 98 17 , , PUNCT ct-9466 98 18 urhausen urhausen ADJ ct-9466 98 19 c c NOUN ct-9466 98 20 , , PUNCT ct-9466 98 21 et et PROPN ct-9466 98 22 al al PROPN ct-9466 98 23 : : PUNCT ct-9466 98 24 proliferative proliferative ADJ ct-9466 98 25 and and CCONJ ct-9466 98 26 apoptotic apoptotic ADJ ct-9466 98 27 changes change NOUN ct-9466 98 28 in in ADP ct-9466 98 29 the the DET ct-9466 98 30 healthy healthy ADJ ct-9466 98 31 canine canine NOUN ct-9466 98 32 endometrium endometrium NOUN ct-9466 98 33 and and CCONJ ct-9466 98 34 in in ADP ct-9466 98 35 cystic cystic ADJ ct-9466 98 36 endometrial endometrial ADJ ct-9466 98 37 hyperplasia hyperplasia NOUN ct-9466 98 38 . . PUNCT ct-9466 99 1 theriogenology theriogenology NOUN ct-9466 99 2 2018;114:14 2018;114:14 PROPN ct-9466 99 3 - - SYM ct-9466 99 4 24 24 NUM ct-9466 99 5 . . PUNCT ct-9466 99 6 14 14 NUM ct-9466 99 7 . . X ct-9466 100 1 de de PROPN ct-9466 100 2 bosschere bosschere ADP ct-9466 100 3 h h PROPN ct-9466 100 4 , , PUNCT ct-9466 100 5 ducatelle ducatelle NOUN ct-9466 100 6 r r NOUN ct-9466 100 7 , , PUNCT ct-9466 100 8 vermeirsch vermeirsch ADJ ct-9466 100 9 h h NOUN ct-9466 100 10 , , PUNCT ct-9466 100 11 et et PROPN ct-9466 100 12 al al PROPN ct-9466 100 13 : : PUNCT ct-9466 100 14 cystic cystic ADJ ct-9466 100 15 endometrial endometrial ADJ ct-9466 100 16 hyperplasia hyperplasia NOUN ct-9466 100 17 - - PUNCT ct-9466 100 18 pyometra pyometra NOUN ct-9466 100 19 complex complex NOUN ct-9466 100 20 in in ADP ct-9466 100 21 the the DET ct-9466 100 22 bitch bitch NOUN ct-9466 100 23 : : PUNCT ct-9466 100 24 should should AUX ct-9466 100 25 the the DET ct-9466 100 26 two two NUM ct-9466 100 27 entities entity NOUN ct-9466 100 28 be be AUX ct-9466 100 29 disconnected disconnect VERB ct-9466 100 30 ? ? PUNCT ct-9466 101 1 theriogenology theriogenology NOUN ct-9466 101 2 2001;55:1509 2001;55:1509 PROPN ct-9466 101 3 - - SYM ct-9466 101 4 1519 1519 NUM ct-9466 101 5 . . PUNCT ct-9466 102 1 15 15 NUM ct-9466 102 2 . . PUNCT ct-9466 102 3 moxon moxon PROPN ct-9466 102 4 r r PROPN ct-9466 102 5 , , PUNCT ct-9466 102 6 whiteside whiteside PROPN ct-9466 102 7 h h PROPN ct-9466 102 8 , , PUNCT ct-9466 102 9 england england PROPN ct-9466 102 10 gcw gcw PROPN ct-9466 102 11 : : PUNCT ct-9466 102 12 prevalence prevalence NOUN ct-9466 102 13 of of ADP ct-9466 102 14 ultrasound ultrasound NOUN ct-9466 102 15 - - PUNCT ct-9466 102 16 determined determine VERB ct-9466 102 17 cystic cystic ADJ ct-9466 102 18 endometrial endometrial ADJ ct-9466 102 19 hyperplasia hyperplasia NOUN ct-9466 102 20 and and CCONJ ct-9466 102 21 the the DET ct-9466 102 22 relationship relationship NOUN ct-9466 102 23 with with ADP ct-9466 102 24 age age NOUN ct-9466 102 25 in in ADP ct-9466 102 26 dogs dog NOUN ct-9466 102 27 . . PUNCT ct-9466 103 1 theriogenology theriogenology NOUN ct-9466 103 2 2016;86:976–980 2016;86:976–980 PROPN ct-9466 103 3 . . PUNCT ct-9466 104 1 16 16 NUM ct-9466 104 2 . . PUNCT ct-9466 105 1 fieni fieni PROPN ct-9466 105 2 f f PROPN ct-9466 105 3 , , PUNCT ct-9466 105 4 topie topie ADJ ct-9466 105 5 e e NOUN ct-9466 105 6 , , PUNCT ct-9466 105 7 cogny cogny NOUN ct-9466 105 8 a a DET ct-9466 105 9 : : PUNCT ct-9466 105 10 medical medical ADJ ct-9466 105 11 treatment treatment NOUN ct-9466 105 12 of of ADP ct-9466 105 13 pyometra pyometra NOUN ct-9466 105 14 in in ADP ct-9466 105 15 dogs dog NOUN ct-9466 105 16 . . PUNCT ct-9466 106 1 reprod reprod PROPN ct-9466 106 2 domestic domestic ADJ ct-9466 106 3 anim anim NOUN ct-9466 106 4 2014;49 2014;49 NUM ct-9466 106 5 suppl suppl NOUN ct-9466 106 6 2:28 2:28 NUM ct-9466 106 7 - - SYM ct-9466 106 8 32 32 NUM ct-9466 106 9 . . PUNCT ct-9466 107 1 17 17 NUM ct-9466 107 2 . . PUNCT ct-9466 107 3 voorwald voorwald PROPN ct-9466 108 1 fa fa PROPN ct-9466 108 2 , , PUNCT ct-9466 108 3 marchi marchi PROPN ct-9466 108 4 fa fa PROPN ct-9466 108 5 , , PUNCT ct-9466 108 6 villacis villacis PROPN ct-9466 108 7 ra ra PROPN ct-9466 108 8 , , PUNCT ct-9466 108 9 et et PROPN ct-9466 108 10 al al PROPN ct-9466 108 11 : : PUNCT ct-9466 108 12 molecular molecular ADJ ct-9466 108 13 expression expression NOUN ct-9466 108 14 profile profile NOUN ct-9466 108 15 reveals reveal VERB ct-9466 108 16 potential potential ADJ ct-9466 108 17 biomarkers biomarker NOUN ct-9466 108 18 and and CCONJ ct-9466 108 19 therapeutic therapeutic ADJ ct-9466 108 20 targets target NOUN ct-9466 108 21 in in ADP ct-9466 108 22 canine canine ADJ ct-9466 108 23 endometrial endometrial ADJ ct-9466 108 24 lesions lesion NOUN ct-9466 108 25 . . PUNCT ct-9466 109 1 plos plos PROPN ct-9466 109 2 one one NUM ct-9466 109 3 2015;10 2015;10 NUM ct-9466 109 4 : : PUNCT ct-9466 109 5 e0133894 e0133894 PROPN ct-9466 109 6 . . PUNCT ct-9466 109 7 doi doi PROPN ct-9466 109 8 : : PUNCT ct-9466 109 9 10.1371 10.1371 NUM ct-9466 109 10 / / SYM ct-9466 109 11 journal.pone.0133894 journal.pone.0133894 PROPN ct-9466 109 12 . . PROPN ct-9466 109 13 18 18 NUM ct-9466 109 14 . . PUNCT ct-9466 110 1 bukowska bukowska PROPN ct-9466 110 2 d d PROPN ct-9466 110 3 , , PUNCT ct-9466 110 4 kempisty kempisty PROPN ct-9466 110 5 b b PROPN ct-9466 110 6 , , PUNCT ct-9466 110 7 zawierucha zawierucha PROPN ct-9466 110 8 p p NOUN ct-9466 110 9 , , PUNCT ct-9466 110 10 et et PROPN ct-9466 110 11 al al PROPN ct-9466 110 12 : : PUNCT ct-9466 110 13 microarray microarray VERB ct-9466 110 14 analysis analysis NOUN ct-9466 110 15 of of ADP ct-9466 110 16 inflammatory inflammatory ADJ ct-9466 110 17 response response NOUN ct-9466 110 18 - - PUNCT ct-9466 110 19 related relate VERB ct-9466 110 20 gene gene NOUN ct-9466 110 21 expression expression NOUN ct-9466 110 22 in in ADP ct-9466 110 23 the the DET ct-9466 110 24 uteri uteri NOUN ct-9466 110 25 of of ADP ct-9466 110 26 dogs dog NOUN ct-9466 110 27 with with ADP ct-9466 110 28 pyometra pyometra NOUN ct-9466 110 29 . . PUNCT ct-9466 111 1 j j PROPN ct-9466 111 2 biol biol PROPN ct-9466 111 3 regul regul PROPN ct-9466 111 4 homeost homeost ADJ ct-9466 111 5 agents agent NOUN ct-9466 111 6 2014;28:637 2014;28:637 NUM ct-9466 111 7 - - SYM ct-9466 111 8 648 648 NUM ct-9466 111 9 . . PUNCT ct-9466 111 10 19 19 NUM ct-9466 111 11 . . PUNCT ct-9466 112 1 singh singh PROPN ct-9466 112 2 lk lk PROPN ct-9466 112 3 , , PUNCT ct-9466 112 4 patra patra PROPN ct-9466 112 5 mk mk PROPN ct-9466 112 6 , , PUNCT ct-9466 112 7 mishra mishra PROPN ct-9466 112 8 gk gk PROPN ct-9466 112 9 , , PUNCT ct-9466 112 10 et et PROPN ct-9466 112 11 al al PROPN ct-9466 112 12 : : PUNCT ct-9466 112 13 endometrial endometrial ADJ ct-9466 112 14 transcripts transcript NOUN ct-9466 112 15 of of ADP ct-9466 112 16 proinflammatory proinflammatory ADJ ct-9466 112 17 cytokine cytokine NOUN ct-9466 112 18 and and CCONJ ct-9466 112 19 enzymes enzyme NOUN ct-9466 112 20 in in ADP ct-9466 112 21 prostaglandin prostaglandin NOUN ct-9466 112 22 synthesis synthesis NOUN ct-9466 112 23 are be AUX ct-9466 112 24 upregulated upregulate VERB ct-9466 112 25 in in ADP ct-9466 112 26 the the DET ct-9466 112 27 bitches bitch NOUN ct-9466 112 28 with with ADP ct-9466 112 29 atrophic atrophic ADJ ct-9466 112 30 pyometra pyometra NOUN ct-9466 112 31 . . PUNCT ct-9466 113 1 vet vet NOUN ct-9466 113 2 immunol immunol NOUN ct-9466 113 3 immunopathol immunopathol VERB ct-9466 113 4 2018;205:65 2018;205:65 NUM ct-9466 113 5 - - SYM ct-9466 113 6 71 71 NUM ct-9466 113 7 . . NOUN ct-9466 113 8 20 20 NUM ct-9466 113 9 . . PUNCT ct-9466 114 1 hara hara PROPN ct-9466 114 2 t t PROPN ct-9466 114 3 , , PUNCT ct-9466 114 4 tanegashima tanegashima PROPN ct-9466 114 5 k k NOUN ct-9466 114 6 : : PUNCT ct-9466 114 7 pleiotropic pleiotropic ADJ ct-9466 114 8 functions function NOUN ct-9466 114 9 of of ADP ct-9466 114 10 the the DET ct-9466 114 11 cxc cxc NOUN ct-9466 114 12 - - PUNCT ct-9466 114 13 type type NOUN ct-9466 114 14 chemokine chemokine ADJ ct-9466 114 15 cxcl14 cxcl14 NOUN ct-9466 114 16 in in ADP ct-9466 114 17 mammals mammal NOUN ct-9466 114 18 . . PUNCT ct-9466 115 1 j j PROPN ct-9466 115 2 biochem biochem PROPN ct-9466 115 3 2012;151:469 2012;151:469 NUM ct-9466 115 4 - - SYM ct-9466 115 5 476 476 NUM ct-9466 115 6 . . PUNCT ct-9466 115 7 21 21 NUM ct-9466 115 8 . . X ct-9466 116 1 cole cole PROPN ct-9466 116 2 am am PROPN ct-9466 116 3 , , PUNCT ct-9466 116 4 ganz ganz PROPN ct-9466 116 5 t t PROPN ct-9466 116 6 , , PUNCT ct-9466 116 7 liese liese PROPN ct-9466 116 8 am am PROPN ct-9466 116 9 , , PUNCT ct-9466 116 10 et et PROPN ct-9466 116 11 al al PROPN ct-9466 116 12 : : PUNCT ct-9466 116 13 cutting cut VERB ct-9466 116 14 edge edge NOUN ct-9466 116 15 : : PUNCT ct-9466 116 16 ifn ifn PROPN ct-9466 116 17 - - PUNCT ct-9466 116 18 inducible inducible ADJ ct-9466 116 19 elr elr PROPN ct-9466 116 20 - - ADJ ct-9466 116 21 cxc cxc ADJ ct-9466 116 22 chemokines chemokine NOUN ct-9466 116 23 display display VERB ct-9466 116 24 defensin defensin NOUN ct-9466 116 25 - - PUNCT ct-9466 116 26 like like ADJ ct-9466 116 27 antimicrobial antimicrobial ADJ ct-9466 116 28 activity activity NOUN ct-9466 116 29 . . PUNCT ct-9466 117 1 j j PROPN ct-9466 117 2 immunol immunol NOUN ct-9466 117 3 2001;167:623 2001;167:623 NUM ct-9466 117 4 - - SYM ct-9466 117 5 627 627 NUM ct-9466 117 6 . . PUNCT ct-9466 118 1 22 22 NUM ct-9466 118 2 . . PUNCT ct-9466 119 1 dufour dufour PROPN ct-9466 119 2 jh jh PROPN ct-9466 119 3 , , PUNCT ct-9466 119 4 michelle michelle PROPN ct-9466 119 5 d d PROPN ct-9466 119 6 , , PUNCT ct-9466 119 7 liu liu PROPN ct-9466 119 8 mt mt PROPN ct-9466 119 9 , , PUNCT ct-9466 119 10 et et PROPN ct-9466 119 11 al al PROPN ct-9466 119 12 : : PUNCT ct-9466 119 13 ifn ifn PROPN ct-9466 119 14 - - PUNCT ct-9466 119 15 gamma gamma NOUN ct-9466 119 16 inducible inducible ADJ ct-9466 119 17 protein protein NOUN ct-9466 119 18 10 10 NUM ct-9466 119 19 ( ( PUNCT ct-9466 119 20 ip-10 ip-10 X ct-9466 119 21 ; ; PUNCT ct-9466 119 22 cxcl10)-deficient cxcl10)-deficient NOUN ct-9466 119 23 mice mouse NOUN ct-9466 119 24 reveal reveal VERB ct-9466 119 25 a a DET ct-9466 119 26 role role NOUN ct-9466 119 27 for for ADP ct-9466 119 28 ip-10 ip-10 X ct-9466 119 29 in in ADP ct-9466 119 30 effector effector NOUN ct-9466 119 31 t t PROPN ct-9466 119 32 cell cell NOUN ct-9466 119 33 generation generation NOUN ct-9466 119 34 and and CCONJ ct-9466 119 35 trafficking trafficking NOUN ct-9466 119 36 . . PUNCT ct-9466 120 1 j j PROPN ct-9466 120 2 immunol immunol NOUN ct-9466 120 3 2002;168:3195 2002;168:3195 NUM ct-9466 120 4 - - SYM ct-9466 120 5 3204 3204 NUM ct-9466 120 6 . . PUNCT ct-9466 121 1 23 23 NUM ct-9466 121 2 . . PUNCT ct-9466 122 1 silva silva PROPN ct-9466 122 2 e e PROPN ct-9466 122 3 , , PUNCT ct-9466 122 4 leitão leitão PROPN ct-9466 122 5 s s PROPN ct-9466 122 6 , , PUNCT ct-9466 122 7 henriques henrique NOUN ct-9466 122 8 s s PROPN ct-9466 122 9 , , PUNCT ct-9466 122 10 et et PROPN ct-9466 122 11 al al PROPN ct-9466 122 12 : : PUNCT ct-9466 122 13 gene gene NOUN ct-9466 122 14 transcription transcription NOUN ct-9466 122 15 of of ADP ct-9466 122 16 tlr2 tlr2 PROPN ct-9466 122 17 , , PUNCT ct-9466 122 18 tlr4 tlr4 PROPN ct-9466 122 19 , , PUNCT ct-9466 122 20 lps lps PROPN ct-9466 122 21 ligands ligand NOUN ct-9466 122 22 and and CCONJ ct-9466 122 23 prostaglandin prostaglandin NOUN ct-9466 122 24 synthesis synthesis NOUN ct-9466 122 25 enzymes enzyme NOUN ct-9466 122 26 are be AUX ct-9466 122 27 up up ADV ct-9466 122 28 - - PUNCT ct-9466 122 29 regulated regulate VERB ct-9466 122 30 in in ADP ct-9466 122 31 canine canine NOUN ct-9466 122 32 uteri uteri NOUN ct-9466 122 33 with with ADP ct-9466 122 34 cystic cystic ADJ ct-9466 122 35 endometrial endometrial ADJ ct-9466 122 36 hyperplasia hyperplasia NOUN ct-9466 122 37 - - PUNCT ct-9466 122 38 pyometra pyometra NOUN ct-9466 122 39 complex complex NOUN ct-9466 122 40 . . PUNCT ct-9466 123 1 j j PROPN ct-9466 123 2 reprod reprod PROPN ct-9466 123 3 immunol immunol PROPN ct-9466 123 4 2010;84:66 2010;84:66 PROPN ct-9466 123 5 - - PUNCT ct-9466 123 6 74 74 NUM ct-9466 123 7 . . PUNCT ct-9466 124 1 24 24 NUM ct-9466 124 2 . . PUNCT ct-9466 125 1 kida kida PROPN ct-9466 125 2 k k PROPN ct-9466 125 3 , , PUNCT ct-9466 125 4 baba baba PROPN ct-9466 125 5 e e PROPN ct-9466 125 6 , , PUNCT ct-9466 125 7 torii torii PROPN ct-9466 125 8 r r NOUN ct-9466 125 9 , , PUNCT ct-9466 125 10 et et PROPN ct-9466 125 11 al al PROPN ct-9466 125 12 : : PUNCT ct-9466 125 13 lactoferrin lactoferrin NOUN ct-9466 125 14 expression expression NOUN ct-9466 125 15 in in ADP ct-9466 125 16 the the DET ct-9466 125 17 canine canine NOUN ct-9466 125 18 uterus uterus NOUN ct-9466 125 19 during during ADP ct-9466 125 20 the the DET ct-9466 125 21 estrous estrous ADJ ct-9466 125 22 cycle cycle NOUN ct-9466 125 23 and and CCONJ ct-9466 125 24 with with ADP ct-9466 125 25 pyometra pyometra NOUN ct-9466 125 26 . . PUNCT ct-9466 126 1 theriogenology theriogenology NOUN ct-9466 126 2 2006;66:1325 2006;66:1325 PROPN ct-9466 126 3 - - SYM ct-9466 126 4 1333 1333 NUM ct-9466 126 5 . . PUNCT ct-9466 127 1 25 25 NUM ct-9466 127 2 . . X ct-9466 127 3 rubio rubio PROPN ct-9466 127 4 a a NOUN ct-9466 127 5 , , PUNCT ct-9466 127 6 boyen boyen NOUN ct-9466 127 7 f f NOUN ct-9466 127 8 , , PUNCT ct-9466 127 9 tas tas PROPN ct-9466 127 10 o o NOUN ct-9466 127 11 , , PUNCT ct-9466 127 12 et et PROPN ct-9466 127 13 al al PROPN ct-9466 127 14 : : PUNCT ct-9466 127 15 bacterial bacterial ADJ ct-9466 127 16 colonization colonization NOUN ct-9466 127 17 of of ADP ct-9466 127 18 the the DET ct-9466 127 19 ovarian ovarian ADJ ct-9466 127 20 bursa bursa NOUN ct-9466 127 21 in in ADP ct-9466 127 22 dogs dog NOUN ct-9466 127 23 with with ADP ct-9466 127 24 clinically clinically ADV ct-9466 127 25 suspected suspect VERB ct-9466 127 26 pyometra pyometra NOUN ct-9466 127 27 and and CCONJ ct-9466 127 28 in in ADP ct-9466 127 29 controls control NOUN ct-9466 127 30 . . PUNCT ct-9466 128 1 theriogenology theriogenology NOUN ct-9466 128 2 2014;82:966 2014;82:966 NUM ct-9466 128 3 - - SYM ct-9466 128 4 971 971 NUM ct-9466 128 5 . . PUNCT ct-9466 129 1 26 26 NUM ct-9466 129 2 . . PUNCT ct-9466 129 3 dhaliwal dhaliwal PROPN ct-9466 129 4 gk gk PROPN ct-9466 129 5 , , PUNCT ct-9466 129 6 wray wray PROPN ct-9466 129 7 c c PROPN ct-9466 129 8 , , PUNCT ct-9466 129 9 noakes noake NOUN ct-9466 129 10 de de ADJ ct-9466 129 11 : : PUNCT ct-9466 129 12 uterine uterine ADJ ct-9466 129 13 bacterial bacterial ADJ ct-9466 129 14 flora flora NOUN ct-9466 129 15 and and CCONJ ct-9466 129 16 uterine uterine ADJ ct-9466 129 17 lesions lesion NOUN ct-9466 129 18 in in ADP ct-9466 129 19 bitches bitch NOUN ct-9466 129 20 with with ADP ct-9466 129 21 cystic cystic ADJ ct-9466 129 22 endometrial endometrial ADJ ct-9466 129 23 hyperplasia hyperplasia NOUN ct-9466 129 24 ( ( PUNCT ct-9466 129 25 pyometra pyometra NOUN ct-9466 129 26 ) ) PUNCT ct-9466 129 27 . . PUNCT ct-9466 130 1 vet vet NOUN ct-9466 130 2 rec rec X ct-9466 130 3 1998;143:659 1998;143:659 NUM ct-9466 130 4 - - SYM ct-9466 130 5 661 661 NUM ct-9466 130 6 . . PUNCT ct-9466 130 7 27 27 NUM ct-9466 130 8 . . PUNCT ct-9466 131 1 mateus mateus PROPN ct-9466 131 2 l l PROPN ct-9466 131 3 , , PUNCT ct-9466 131 4 henrique henrique PROPN ct-9466 131 5 s s PROPN ct-9466 131 6 , , PUNCT ct-9466 131 7 merino merino PROPN ct-9466 131 8 c c NOUN ct-9466 131 9 , , PUNCT ct-9466 131 10 et et PROPN ct-9466 131 11 al al PROPN ct-9466 131 12 : : PUNCT ct-9466 131 13 virulence virulence NOUN ct-9466 131 14 genotypes genotype NOUN ct-9466 131 15 of of ADP ct-9466 131 16 escherichia escherichia NOUN ct-9466 131 17 coli coli NOUN ct-9466 131 18 canine canine NOUN ct-9466 131 19 isolates isolate NOUN ct-9466 131 20 from from ADP ct-9466 131 21 pyometra pyometra NOUN ct-9466 131 22 , , PUNCT ct-9466 131 23 cystitis cystitis NOUN ct-9466 131 24 and and CCONJ ct-9466 131 25 fecal fecal ADJ ct-9466 131 26 origin origin NOUN ct-9466 131 27 . . PUNCT ct-9466 132 1 vet vet NOUN ct-9466 132 2 microbiol microbiol NOUN ct-9466 132 3 2013:166:590 2013:166:590 NUM ct-9466 132 4 - - SYM ct-9466 132 5 594 594 NUM ct-9466 132 6 . . PUNCT ct-9466 133 1 28 28 NUM ct-9466 133 2 . . PUNCT ct-9466 134 1 maluta maluta PROPN ct-9466 134 2 rp rp PROPN ct-9466 134 3 , , PUNCT ct-9466 134 4 borges borge NOUN ct-9466 134 5 ca can AUX ct-9466 134 6 , , PUNCT ct-9466 134 7 berldo berldo PROPN ct-9466 134 8 lg lg NOUN ct-9466 134 9 , , PUNCT ct-9466 134 10 et et PROPN ct-9466 134 11 al al PROPN ct-9466 134 12 : : PUNCT ct-9466 134 13 frequencies frequency NOUN ct-9466 134 14 of of ADP ct-9466 134 15 virulence virulence NOUN ct-9466 134 16 genes gene NOUN ct-9466 134 17 and and CCONJ ct-9466 134 18 pulse pulse NOUN ct-9466 134 19 field field NOUN ct-9466 134 20 gel gel NOUN ct-9466 134 21 electrophoresis electrophoresis NOUN ct-9466 134 22 fingerprints fingerprint NOUN ct-9466 134 23 in in ADP ct-9466 134 24 escherichia escherichia NOUN ct-9466 134 25 coli coli NOUN ct-9466 134 26 isolates isolate NOUN ct-9466 134 27 from from ADP ct-9466 134 28 canine canine NOUN ct-9466 134 29 pyometra pyometra NOUN ct-9466 134 30 . . PUNCT ct-9466 135 1 vet vet NOUN ct-9466 135 2 j j PROPN ct-9466 135 3 2014;202:393 2014;202:393 NUM ct-9466 135 4 - - SYM ct-9466 135 5 395 395 NUM ct-9466 135 6 . . NOUN ct-9466 135 7 29 29 NUM ct-9466 135 8 . . PUNCT ct-9466 136 1 chen chen PROPN ct-9466 136 2 ymm ymm PROPN ct-9466 136 3 , , PUNCT ct-9466 136 4 wright wright PROPN ct-9466 136 5 pj pj PROPN ct-9466 136 6 , , PUNCT ct-9466 136 7 lee lee PROPN ct-9466 136 8 c c PROPN ct-9466 136 9 - - PUNCT ct-9466 136 10 s s PROPN ct-9466 136 11 , , PUNCT ct-9466 136 12 et et PROPN ct-9466 136 13 al al PROPN ct-9466 136 14 : : PUNCT ct-9466 136 15 uropathogenic uropathogenic ADJ ct-9466 136 16 virulence virulence NOUN ct-9466 136 17 factors factor NOUN ct-9466 136 18 in in ADP ct-9466 136 19 isolates isolate NOUN ct-9466 136 20 of of ADP ct-9466 136 21 escherichia escherichia NOUN ct-9466 136 22 coli coli NOUN ct-9466 136 23 from from ADP ct-9466 136 24 clinical clinical ADJ ct-9466 136 25 cases case NOUN ct-9466 136 26 of of ADP ct-9466 136 27 canine canine NOUN ct-9466 136 28 pyometra pyometra NOUN ct-9466 136 29 and and CCONJ ct-9466 136 30 feces fece NOUN ct-9466 136 31 of of ADP ct-9466 136 32 healthy healthy ADJ ct-9466 136 33 bitches bitch NOUN ct-9466 136 34 . . PUNCT ct-9466 137 1 vet vet NOUN ct-9466 137 2 microbiol microbiol PROPN ct-9466 137 3 2003;94:57 2003;94:57 NUM ct-9466 137 4 - - SYM ct-9466 137 5 69 69 NUM ct-9466 137 6 . . PUNCT ct-9466 137 7 30 30 NUM ct-9466 137 8 . . PUNCT ct-9466 138 1 siqueira siqueira PROPN ct-9466 138 2 a a PRON ct-9466 138 3 , , PUNCT ct-9466 138 4 ribeiro ribeiro PROPN ct-9466 138 5 m m PROPN ct-9466 138 6 , , PUNCT ct-9466 138 7 leite leite PROPN ct-9466 138 8 d d PROPN ct-9466 138 9 , , PUNCT ct-9466 138 10 et et PROPN ct-9466 138 11 al al PROPN ct-9466 138 12 : : PUNCT ct-9466 138 13 virulence virulence NOUN ct-9466 138 14 factors factor NOUN ct-9466 138 15 in in ADP ct-9466 138 16 escherichia escherichia NOUN ct-9466 138 17 coli coli NOUN ct-9466 138 18 strains strain NOUN ct-9466 138 19 isolated isolate VERB ct-9466 138 20 from from ADP ct-9466 138 21 urinary urinary ADJ ct-9466 138 22 tract tract NOUN ct-9466 138 23 infection infection NOUN ct-9466 138 24 and and CCONJ ct-9466 138 25 pyometra pyometra ADJ ct-9466 138 26 cases case NOUN ct-9466 138 27 and and CCONJ ct-9466 138 28 from from ADP ct-9466 138 29 feces fece NOUN ct-9466 138 30 of of ADP ct-9466 138 31 healthy healthy ADJ ct-9466 138 32 dogs dog NOUN ct-9466 138 33 . . PUNCT ct-9466 139 1 res re NOUN ct-9466 139 2 vet vet NOUN ct-9466 139 3 sci sci PROPN ct-9466 139 4 2009;86:206 2009;86:206 PROPN ct-9466 139 5 - - SYM ct-9466 139 6 210 210 NUM ct-9466 139 7 . . PUNCT ct-9466 140 1 646clinical 646clinical ADJ ct-9466 140 2 theriogenology theriogenology NOUN ct-9466 140 3 • • NOUN ct-9466 140 4 volume volume NOUN ct-9466 140 5 11 11 NUM ct-9466 140 6 , , PUNCT ct-9466 140 7 number number NOUN ct-9466 140 8 4 4 NUM ct-9466 140 9 • • NOUN ct-9466 140 10 december december PROPN ct-9466 140 11 2019 2019 NUM ct-9466 140 12     SPACE ct-9466 140 13 31 31 NUM ct-9466 140 14 . . PUNCT ct-9466 141 1 wiles wile NOUN ct-9466 141 2 tj tj NOUN ct-9466 141 3 , , PUNCT ct-9466 141 4 mulvey mulvey PROPN ct-9466 141 5 ma ma PROPN ct-9466 141 6 : : PUNCT ct-9466 141 7 the the DET ct-9466 141 8 rtx rtx PROPN ct-9466 141 9 pore pore NOUN ct-9466 141 10 - - PUNCT ct-9466 141 11 forming form VERB ct-9466 141 12 toxin toxin NOUN ct-9466 141 13 alpha alpha NOUN ct-9466 141 14 - - PUNCT ct-9466 141 15 hemolysin hemolysin NOUN ct-9466 141 16 of of ADP ct-9466 141 17 uropathogenic uropathogenic ADJ ct-9466 141 18 escherichia escherichia NOUN ct-9466 141 19 coli coli NOUN ct-9466 141 20 : : PUNCT ct-9466 141 21 progress progress NOUN ct-9466 141 22 and and CCONJ ct-9466 141 23 perspectives perspective NOUN ct-9466 141 24 . . PUNCT ct-9466 142 1 future future ADJ ct-9466 142 2 microbiol microbiol PROPN ct-9466 142 3 2013;8:73 2013;8:73 PROPN ct-9466 142 4 - - PUNCT ct-9466 142 5 84 84 NUM ct-9466 142 6 . . PUNCT ct-9466 143 1 32 32 NUM ct-9466 143 2 . . PUNCT ct-9466 144 1 henriques henrique NOUN ct-9466 144 2 s s PROPN ct-9466 144 3 , , PUNCT ct-9466 144 4 silva silva PROPN ct-9466 144 5 e e PROPN ct-9466 144 6 , , PUNCT ct-9466 144 7 silva silva PROPN ct-9466 144 8 mf mf PROPN ct-9466 144 9 , , PUNCT ct-9466 144 10 et et PROPN ct-9466 144 11 al al PROPN ct-9466 144 12 : : PUNCT ct-9466 144 13 immunomodulation immunomodulation NOUN ct-9466 144 14 in in ADP ct-9466 144 15 the the DET ct-9466 144 16 canine canine NOUN ct-9466 144 17 endometrium endometrium NOUN ct-9466 144 18 by by ADP ct-9466 144 19 uteropathogenic uteropathogenic ADJ ct-9466 144 20 escherichia escherichia NOUN ct-9466 144 21 coli coli NOUN ct-9466 144 22 . . PUNCT ct-9466 145 1 vet vet NOUN ct-9466 145 2 res re NOUN ct-9466 145 3 2016;47:114 2016;47:114 NUM ct-9466 145 4 . . PUNCT ct-9466 146 1 doi doi PROPN ct-9466 146 2 10.1186 10.1186 NUM ct-9466 146 3 / / SYM ct-9466 146 4 s13567 s13567 PROPN ct-9466 146 5 - - PUNCT ct-9466 146 6 016 016 NUM ct-9466 146 7 - - PUNCT ct-9466 146 8 0396 0396 NUM ct-9466 146 9 - - PUNCT ct-9466 146 10 z. z. PROPN ct-9466 146 11 33 33 NUM ct-9466 146 12 . . PUNCT ct-9466 147 1 kuplulu kuplulu PROPN ct-9466 147 2 s s PROPN ct-9466 147 3 , , PUNCT ct-9466 147 4 vural vural ADJ ct-9466 147 5 mr mr PROPN ct-9466 147 6 , , PUNCT ct-9466 147 7 demirel demirel NOUN ct-9466 147 8 a a PRON ct-9466 147 9 , , PUNCT ct-9466 147 10 et et PROPN ct-9466 147 11 al al PROPN ct-9466 147 12 : : PUNCT ct-9466 147 13 the the DET ct-9466 147 14 comparative comparative ADJ ct-9466 147 15 evaluation evaluation NOUN ct-9466 147 16 of of ADP ct-9466 147 17 serum serum NOUN ct-9466 147 18 biochemical biochemical ADJ ct-9466 147 19 , , PUNCT ct-9466 147 20 haematological haematological ADJ ct-9466 147 21 , , PUNCT ct-9466 147 22 bacteriological bacteriological ADJ ct-9466 147 23 and and CCONJ ct-9466 147 24 clinical clinical ADJ ct-9466 147 25 findings finding NOUN ct-9466 147 26 of of ADP ct-9466 147 27 dead dead ADJ ct-9466 147 28 and and CCONJ ct-9466 147 29 recovered recover VERB ct-9466 147 30 bitches bitch NOUN ct-9466 147 31 with with ADP ct-9466 147 32 pyometra pyometra NOUN ct-9466 147 33 in in ADP ct-9466 147 34 the the DET ct-9466 147 35 postoperative postoperative ADJ ct-9466 147 36 process process NOUN ct-9466 147 37 . . PUNCT ct-9466 148 1 acta acta PROPN ct-9466 148 2 vet vet PROPN ct-9466 148 3 - - PUNCT ct-9466 148 4 beograd beograd PROPN ct-9466 148 5 2009;59:193 2009;59:193 PROPN ct-9466 148 6 - - PROPN ct-9466 148 7 204 204 NUM ct-9466 148 8 . . PUNCT ct-9466 149 1 34 34 NUM ct-9466 149 2 . . PUNCT ct-9466 150 1 borresen borresen PROPN ct-9466 150 2 b b PROPN ct-9466 150 3 : : PUNCT ct-9466 150 4 pyometra pyometra NOUN ct-9466 150 5 in in ADP ct-9466 150 6 the the DET ct-9466 150 7 doga doga NOUN ct-9466 150 8 pathophysiological pathophysiological ADJ ct-9466 150 9 investigation investigation NOUN ct-9466 150 10 . . PUNCT ct-9466 151 1 ii ii PROPN ct-9466 151 2 . . PUNCT ct-9466 152 1 anamnestic anamnestic ADJ ct-9466 152 2 , , PUNCT ct-9466 152 3 clinical clinical ADJ ct-9466 152 4 and and CCONJ ct-9466 152 5 reproductive reproductive ADJ ct-9466 152 6 aspects aspect NOUN ct-9466 152 7 . . PUNCT ct-9466 153 1 nord nord PROPN ct-9466 153 2 vet vet NOUN ct-9466 153 3 med me VERB ct-9466 153 4 1979;31:251 1979;31:251 NUM ct-9466 153 5 - - SYM ct-9466 153 6 257 257 NUM ct-9466 153 7 . . NOUN ct-9466 153 8 35 35 NUM ct-9466 153 9 . . PUNCT ct-9466 154 1 maddens madden VERB ct-9466 154 2 b b NUM ct-9466 154 3 , , PUNCT ct-9466 154 4 heiene heiene ADJ ct-9466 154 5 r r NOUN ct-9466 154 6 , , PUNCT ct-9466 154 7 smets smet NOUN ct-9466 154 8 p p NOUN ct-9466 154 9 , , PUNCT ct-9466 154 10 et et PROPN ct-9466 154 11 al al PROPN ct-9466 154 12 : : PUNCT ct-9466 154 13 evaluation evaluation NOUN ct-9466 154 14 of of ADP ct-9466 154 15 kidney kidney NOUN ct-9466 154 16 injury injury NOUN ct-9466 154 17 in in ADP ct-9466 154 18 dogs dog NOUN ct-9466 154 19 with with ADP ct-9466 154 20 pyometra pyometra NOUN ct-9466 154 21 based base VERB ct-9466 154 22 on on ADP ct-9466 154 23 proteinuria proteinuria NOUN ct-9466 154 24 , , PUNCT ct-9466 154 25 renal renal ADJ ct-9466 154 26 histomorphology histomorphology NOUN ct-9466 154 27 , , PUNCT ct-9466 154 28 and and CCONJ ct-9466 154 29 urinary urinary ADJ ct-9466 154 30 biomarkers biomarker NOUN ct-9466 154 31 . . PUNCT ct-9466 155 1 j j PROPN ct-9466 155 2 vet vet NOUN ct-9466 155 3 intern intern NOUN ct-9466 155 4 med me VERB ct-9466 155 5 2011;25:1075 2011;25:1075 PROPN ct-9466 155 6 - - SYM ct-9466 155 7 1083 1083 NUM ct-9466 155 8 . . PUNCT ct-9466 156 1 36 36 NUM ct-9466 156 2 . . PUNCT ct-9466 156 3 asheim asheim PROPN ct-9466 156 4 a a DET ct-9466 156 5 : : PUNCT ct-9466 156 6 renal renal ADJ ct-9466 156 7 function function NOUN ct-9466 156 8 in in ADP ct-9466 156 9 dogs dog NOUN ct-9466 156 10 with with ADP ct-9466 156 11 pyometra pyometra NOUN ct-9466 156 12 . . PUNCT ct-9466 157 1 8 8 NUM ct-9466 157 2 . . X ct-9466 157 3 uterine uterine ADJ ct-9466 157 4 infection infection NOUN ct-9466 157 5 and and CCONJ ct-9466 157 6 the the DET ct-9466 157 7 pathogenesis pathogenesis NOUN ct-9466 157 8 of of ADP ct-9466 157 9 the the DET ct-9466 157 10 renal renal ADJ ct-9466 157 11 dysfunction dysfunction NOUN ct-9466 157 12 . . PUNCT ct-9466 158 1 acta acta PROPN ct-9466 158 2 pathol pathol VERB ct-9466 158 3 microbiol microbiol PROPN ct-9466 158 4 immunol immunol PROPN ct-9466 158 5 scand scand PROPN ct-9466 158 6 1964;60:99 1964;60:99 NUM ct-9466 158 7 - - SYM ct-9466 158 8 107 107 NUM ct-9466 158 9 . . PUNCT ct-9466 159 1 37 37 NUM ct-9466 159 2 . . PUNCT ct-9466 160 1 borresen borresen PROPN ct-9466 160 2 b b PROPN ct-9466 160 3 , , PUNCT ct-9466 160 4 skrede skrede NOUN ct-9466 160 5 s s PART ct-9466 160 6 : : PUNCT ct-9466 160 7 pyometra pyometra NOUN ct-9466 160 8 in in ADP ct-9466 160 9 the the DET ct-9466 160 10 doga doga NOUN ct-9466 160 11 pathophysiological pathophysiological ADJ ct-9466 160 12 investigation investigation NOUN ct-9466 160 13 v. v. ADP ct-9466 160 14 the the DET ct-9466 160 15 presence presence NOUN ct-9466 160 16 of of ADP ct-9466 160 17 intrahepatic intrahepatic ADJ ct-9466 160 18 cholestasis cholestasis NOUN ct-9466 160 19 and and CCONJ ct-9466 160 20 an an DET ct-9466 160 21 “ " PUNCT ct-9466 160 22 acute acute ADJ ct-9466 160 23 phase phase NOUN ct-9466 160 24 reaction reaction NOUN ct-9466 160 25 . . PUNCT ct-9466 160 26 ” " PUNCT ct-9466 160 27 . . PUNCT ct-9466 161 1 nord nord PROPN ct-9466 161 2 vet vet PROPN ct-9466 161 3 med me VERB ct-9466 161 4 1980;32:378 1980;32:378 PROPN ct-9466 161 5 - - SYM ct-9466 161 6 386 386 NUM ct-9466 161 7 . . PUNCT ct-9466 162 1 38 38 NUM ct-9466 162 2 . . PUNCT ct-9466 162 3 plavec plavec PROPN ct-9466 162 4 t t PROPN ct-9466 162 5 , , PUNCT ct-9466 162 6 celinsek celinsek PROPN ct-9466 162 7 b b NOUN ct-9466 162 8 , , PUNCT ct-9466 162 9 dolinar dolinar NOUN ct-9466 162 10 k k NOUN ct-9466 162 11 , , PUNCT ct-9466 162 12 et et PROPN ct-9466 162 13 al al PROPN ct-9466 162 14 : : PUNCT ct-9466 162 15 haemostasis haemostasis NOUN ct-9466 162 16 impairment impairment NOUN ct-9466 162 17 in in ADP ct-9466 162 18 bitches bitch NOUN ct-9466 162 19 with with ADP ct-9466 162 20 pyometra pyometra NOUN ct-9466 162 21 . . PUNCT ct-9466 163 1 acta acta PROPN ct-9466 163 2 vet vet PROPN ct-9466 163 3 beograd beograd PROPN ct-9466 163 4 2006;56:529 2006;56:529 PROPN ct-9466 163 5 - - SYM ct-9466 163 6 540 540 NUM ct-9466 163 7 . . PUNCT ct-9466 163 8 39 39 NUM ct-9466 163 9 . . PUNCT ct-9466 164 1 hagman hagman NOUN ct-9466 164 2 r r PROPN ct-9466 164 3 , , PUNCT ct-9466 164 4 kindahl kindahl PROPN ct-9466 164 5 h h NOUN ct-9466 164 6 , , PUNCT ct-9466 164 7 lagerstadt lagerstadt NOUN ct-9466 164 8 as as ADP ct-9466 164 9 : : PUNCT ct-9466 164 10 pyometra pyometra NOUN ct-9466 164 11 in in ADP ct-9466 164 12 bitches bitch NOUN ct-9466 164 13 induces induce VERB ct-9466 164 14 elevated elevated ADJ ct-9466 164 15 plasma plasma NOUN ct-9466 164 16 endotoxin endotoxin NOUN ct-9466 164 17 and and CCONJ ct-9466 164 18 prostaglandin prostaglandin VERB ct-9466 164 19 f2alpha f2alpha NOUN ct-9466 164 20 metabolite metabolite NOUN ct-9466 164 21 levels level NOUN ct-9466 164 22 . . PUNCT ct-9466 165 1 acta acta PROPN ct-9466 165 2 vet vet PROPN ct-9466 165 3 scand scand PROPN ct-9466 165 4 2006;47:55 2006;47:55 NUM ct-9466 165 5 - - SYM ct-9466 165 6 68 68 NUM ct-9466 165 7 . . PUNCT ct-9466 165 8 40 40 NUM ct-9466 165 9 . . PUNCT ct-9466 166 1 fransson fransson PROPN ct-9466 166 2 ba ba PROPN ct-9466 166 3 , , PUNCT ct-9466 166 4 lagerstadt lagerstadt VERB ct-9466 166 5 a a DET ct-9466 166 6 - - PUNCT ct-9466 166 7 s s NOUN ct-9466 166 8 , , PUNCT ct-9466 166 9 bergstrom bergstrom PROPN ct-9466 166 10 a a PRON ct-9466 166 11 , , PUNCT ct-9466 166 12 et et PROPN ct-9466 166 13 al al PROPN ct-9466 166 14 : : PUNCT ct-9466 166 15 c c PROPN ct-9466 166 16 reactive reactive ADJ ct-9466 166 17 protin protin NOUN ct-9466 166 18 , , PUNCT ct-9466 166 19 tumor tumor NOUN ct-9466 166 20 necrosis necrosis NOUN ct-9466 166 21 fact fact NOUN ct-9466 166 22 alpha alpha NOUN ct-9466 166 23 , , PUNCT ct-9466 166 24 and and CCONJ ct-9466 166 25 interleukin-6 interleukin-6 NUM ct-9466 166 26 in in ADP ct-9466 166 27 dogs dog NOUN ct-9466 166 28 with with ADP ct-9466 166 29 pyometra pyometra NOUN ct-9466 166 30 and and CCONJ ct-9466 166 31 sirs sir NOUN ct-9466 166 32 . . PUNCT ct-9466 167 1 j j PROPN ct-9466 167 2 vet vet PROPN ct-9466 167 3 emerg emerg PROPN ct-9466 167 4 crit crit PROPN ct-9466 167 5 care care NOUN ct-9466 167 6 2007;17:373 2007;17:373 PROPN ct-9466 167 7 - - SYM ct-9466 167 8 381 381 NUM ct-9466 167 9 . . NOUN ct-9466 167 10 41 41 NUM ct-9466 167 11 . . PUNCT ct-9466 168 1 karlsson karlsson PROPN ct-9466 168 2 i i PROPN ct-9466 168 3 , , PUNCT ct-9466 168 4 hagman hagman PROPN ct-9466 168 5 r r PROPN ct-9466 168 6 , , PUNCT ct-9466 168 7 johannisson johannisson NOUN ct-9466 168 8 a a NOUN ct-9466 168 9 , , PUNCT ct-9466 168 10 et et PROPN ct-9466 168 11 al al PROPN ct-9466 168 12 : : PUNCT ct-9466 168 13 cytokines cytokine NOUN ct-9466 168 14 as as ADP ct-9466 168 15 immunological immunological ADJ ct-9466 168 16 markers marker NOUN ct-9466 168 17 for for ADP ct-9466 168 18 systemic systemic ADJ ct-9466 168 19 inflammation inflammation NOUN ct-9466 168 20 in in ADP ct-9466 168 21 dogs dog NOUN ct-9466 168 22 with with ADP ct-9466 168 23 pyometra pyometra NOUN ct-9466 168 24 . . PUNCT ct-9466 169 1 reprod reprod PROPN ct-9466 169 2 domest domest PROPN ct-9466 169 3 anim anim NOUN ct-9466 169 4 2012;47 2012;47 PROPN ct-9466 169 5 suppl suppl PROPN ct-9466 170 1 6:337 6:337 PROPN ct-9466 170 2 - - PUNCT ct-9466 170 3 341 341 NUM ct-9466 170 4 . . PUNCT ct-9466 170 5 42 42 NUM ct-9466 170 6 . . PUNCT ct-9466 171 1 egenvall egenvall PROPN ct-9466 171 2 a a PRON ct-9466 171 3 , , PUNCT ct-9466 171 4 hagman hagman NOUN ct-9466 171 5 r r PROPN ct-9466 171 6 , , PUNCT ct-9466 171 7 bonnett bonnett PROPN ct-9466 171 8 bn bn PROPN ct-9466 171 9 , , PUNCT ct-9466 171 10 et et PROPN ct-9466 171 11 al al PROPN ct-9466 171 12 : : PUNCT ct-9466 171 13 breed breed NOUN ct-9466 171 14 risk risk NOUN ct-9466 171 15 of of ADP ct-9466 171 16 pyometra pyometra NOUN ct-9466 171 17 in in ADP ct-9466 171 18 insured insure VERB ct-9466 171 19 dogs dog NOUN ct-9466 171 20 in in ADP ct-9466 171 21 sweden sweden PROPN ct-9466 171 22 . . PUNCT ct-9466 172 1 j j PROPN ct-9466 172 2 vet vet NOUN ct-9466 172 3 intern intern NOUN ct-9466 172 4 med me VERB ct-9466 172 5 2001;15:530 2001;15:530 PROPN ct-9466 172 6 - - SYM ct-9466 172 7 538 538 NUM ct-9466 172 8 . . PUNCT ct-9466 173 1 43 43 NUM ct-9466 173 2 . . PUNCT ct-9466 174 1 hagman hagman NOUN ct-9466 174 2 r r NOUN ct-9466 174 3 : : PUNCT ct-9466 174 4 pyometra pyometra NOUN ct-9466 174 5 in in ADP ct-9466 174 6 small small ADJ ct-9466 174 7 animals animal NOUN ct-9466 174 8 . . PUNCT ct-9466 175 1 vet vet NOUN ct-9466 175 2 clin clin PROPN ct-9466 175 3 north north PROPN ct-9466 175 4 am be AUX ct-9466 175 5 small small ADJ ct-9466 175 6 anim anim NOUN ct-9466 175 7 pract pract NOUN ct-9466 175 8 2018;48:639 2018;48:639 PROPN ct-9466 175 9 - - PUNCT ct-9466 175 10 661 661 NUM ct-9466 175 11 . . PUNCT ct-9466 176 1 44 44 NUM ct-9466 176 2 . . PUNCT ct-9466 177 1 fantoni fantoni PROPN ct-9466 177 2 d d PROPN ct-9466 177 3 , , PUNCT ct-9466 177 4 shih shih PROPN ct-9466 177 5 ac ac PROPN ct-9466 177 6 : : PUNCT ct-9466 177 7 perioperative perioperative ADJ ct-9466 177 8 fluid fluid NOUN ct-9466 177 9 therapy therapy NOUN ct-9466 177 10 . . PUNCT ct-9466 178 1 vet vet NOUN ct-9466 178 2 clin clin PROPN ct-9466 178 3 north north PROPN ct-9466 178 4 am be AUX ct-9466 178 5 small small ADJ ct-9466 178 6 anim anim NOUN ct-9466 178 7 pract pract NOUN ct-9466 178 8 2017;47:423 2017;47:423 NOUN ct-9466 178 9 - - SYM ct-9466 178 10 434 434 NUM ct-9466 178 11 . . PUNCT ct-9466 179 1 45 45 NUM ct-9466 179 2 . . PUNCT ct-9466 180 1 lopate lopate PROPN ct-9466 180 2 c c NOUN ct-9466 180 3 : : PUNCT ct-9466 180 4 pyometra pyometra ADJ ct-9466 180 5 , , PUNCT ct-9466 180 6 cystic cystic ADJ ct-9466 180 7 endometrial endometrial ADJ ct-9466 180 8 hyperplasia hyperplasia NOUN ct-9466 180 9 ( ( PUNCT ct-9466 180 10 hydrometra hydrometra PROPN ct-9466 180 11 , , PUNCT ct-9466 180 12 mucometra mucometra ADJ ct-9466 180 13 , , PUNCT ct-9466 180 14 hematometra hematometra NOUN ct-9466 180 15 ) ) PUNCT ct-9466 180 16 . . PUNCT ct-9466 181 1 in in ADP ct-9466 181 2 : : PUNCT ct-9466 181 3 greco greco PROPN ct-9466 181 4 ds ds PROPN ct-9466 181 5 , , PUNCT ct-9466 181 6 davidson davidson PROPN ct-9466 181 7 ap ap PROPN ct-9466 181 8 , , PUNCT ct-9466 181 9 editors editor NOUN ct-9466 181 10 . . PUNCT ct-9466 182 1 blackwell blackwell PROPN ct-9466 182 2 ’s ’s PART ct-9466 182 3 five five NUM ct-9466 182 4 - - PUNCT ct-9466 182 5 minute minute NOUN ct-9466 182 6 veterinary veterinary NOUN ct-9466 182 7 consult consult VERB ct-9466 182 8 clinical clinical ADJ ct-9466 182 9 companion companion NOUN ct-9466 182 10 , , PUNCT ct-9466 182 11 small small ADJ ct-9466 182 12 animal animal NOUN ct-9466 182 13 endocrinology endocrinology NOUN ct-9466 182 14 and and CCONJ ct-9466 182 15 reproduction reproduction NOUN ct-9466 182 16 . . PUNCT ct-9466 183 1 hoboken hoboken PROPN ct-9466 183 2 , , PUNCT ct-9466 183 3 nj nj PROPN ct-9466 183 4 ; ; PUNCT ct-9466 183 5 wiley wiley NOUN ct-9466 183 6 - - PUNCT ct-9466 183 7 blackwell blackwell PROPN ct-9466 183 8 : : PUNCT ct-9466 183 9 2017 2017 NUM ct-9466 183 10 . . PUNCT ct-9466 184 1 p. p. NOUN ct-9466 184 2 53 53 NUM ct-9466 184 3 - - SYM ct-9466 184 4 62 62 NUM ct-9466 184 5 . . PUNCT ct-9466 185 1 46 46 NUM ct-9466 185 2 . . PUNCT ct-9466 185 3 declue declue NOUN ct-9466 185 4 a a DET ct-9466 185 5 : : PUNCT ct-9466 185 6 sepsis sepsis NOUN ct-9466 185 7 and and CCONJ ct-9466 185 8 the the DET ct-9466 185 9 systemic systemic ADJ ct-9466 185 10 inflammatory inflammatory ADJ ct-9466 185 11 response response NOUN ct-9466 185 12 syndrome syndrome NOUN ct-9466 185 13 . . PUNCT ct-9466 186 1 in in ADP ct-9466 186 2 : : PUNCT ct-9466 186 3 ettinger ettinger PROPN ct-9466 186 4 sj sj PROPN ct-9466 186 5 , , PUNCT ct-9466 186 6 feldman feldman PROPN ct-9466 186 7 ec ec PROPN ct-9466 186 8 , , PUNCT ct-9466 186 9 cote cote PROPN ct-9466 186 10 e e PROPN ct-9466 186 11 , , PUNCT ct-9466 186 12 editors editor NOUN ct-9466 186 13 . . PUNCT ct-9466 187 1 textbook textbook NOUN ct-9466 187 2 of of ADP ct-9466 187 3 veterinary veterinary ADJ ct-9466 187 4 internal internal ADJ ct-9466 187 5 medicine medicine NOUN ct-9466 187 6 : : PUNCT ct-9466 187 7 diseases disease NOUN ct-9466 187 8 of of ADP ct-9466 187 9 the the DET ct-9466 187 10 dogs dog NOUN ct-9466 187 11 and and CCONJ ct-9466 187 12 cat cat NOUN ct-9466 187 13 . . PUNCT ct-9466 188 1 8th 8th PROPN ct-9466 188 2 edition edition PROPN ct-9466 188 3 , , PUNCT ct-9466 188 4 st st PROPN ct-9466 188 5 louis louis PROPN ct-9466 188 6 ; ; PUNCT ct-9466 188 7 elsevier elsevier NOUN ct-9466 188 8 : : PUNCT ct-9466 188 9 2016 2016 NUM ct-9466 188 10 . . PUNCT ct-9466 189 1 p. p. NOUN ct-9466 189 2 554 554 NUM ct-9466 189 3 - - SYM ct-9466 189 4 560 560 NUM ct-9466 189 5 . . PUNCT ct-9466 189 6 47 47 NUM ct-9466 189 7 . . PUNCT ct-9466 190 1 hagman hagman NOUN ct-9466 190 2 r r NOUN ct-9466 190 3 , , PUNCT ct-9466 190 4 greko greko ADJ ct-9466 190 5 c c NOUN ct-9466 190 6 : : PUNCT ct-9466 190 7 antimicrobial antimicrobial ADJ ct-9466 190 8 resistance resistance NOUN ct-9466 190 9 in in ADP ct-9466 190 10 escherichia escherichia NOUN ct-9466 190 11 coli coli NOUN ct-9466 190 12 isolated isolate VERB ct-9466 190 13 from from ADP ct-9466 190 14 bitches bitch NOUN ct-9466 190 15 with with ADP ct-9466 190 16 pyometra pyometra NOUN ct-9466 190 17 and and CCONJ ct-9466 190 18 from from ADP ct-9466 190 19 urine urine NOUN ct-9466 190 20 samples sample NOUN ct-9466 190 21 from from ADP ct-9466 190 22 other other ADJ ct-9466 190 23 dogs dog NOUN ct-9466 190 24 . . PUNCT ct-9466 191 1 vet vet NOUN ct-9466 191 2 rec rec X ct-9466 191 3 2005;157:193 2005;157:193 NUM ct-9466 191 4 - - SYM ct-9466 191 5 196 196 NUM ct-9466 191 6 . . PUNCT ct-9466 191 7 48 48 NUM ct-9466 191 8 . . PUNCT ct-9466 192 1 fieni fieni PROPN ct-9466 192 2 f f NOUN ct-9466 192 3 : : PUNCT ct-9466 192 4 clinical clinical ADJ ct-9466 192 5 evaluation evaluation NOUN ct-9466 192 6 of of ADP ct-9466 192 7 the the DET ct-9466 192 8 use use NOUN ct-9466 192 9 of of ADP ct-9466 192 10 aglepristone aglepristone NOUN ct-9466 192 11 , , PUNCT ct-9466 192 12 with with ADP ct-9466 192 13 or or CCONJ ct-9466 192 14 without without ADP ct-9466 192 15 cloprostenol cloprostenol NOUN ct-9466 192 16 , , PUNCT ct-9466 192 17 to to PART ct-9466 192 18 treat treat VERB ct-9466 192 19 cystic cystic ADJ ct-9466 192 20 endometrial endometrial ADJ ct-9466 192 21 hyperplasia hyperplasia NOUN ct-9466 192 22 - - PUNCT ct-9466 192 23 pyometra pyometra NOUN ct-9466 192 24 complex complex NOUN ct-9466 192 25 in in ADP ct-9466 192 26 bitches bitch NOUN ct-9466 192 27 . . PUNCT ct-9466 193 1 theriogenology theriogenology NOUN ct-9466 193 2 2006;66:1550 2006;66:1550 NUM ct-9466 193 3 - - SYM ct-9466 193 4 1556 1556 NUM ct-9466 193 5 . . PUNCT ct-9466 193 6 49 49 NUM ct-9466 193 7 . . PUNCT ct-9466 194 1 trasch trasch PROPN ct-9466 194 2 k k PROPN ct-9466 194 3 wehrend wehrend PROPN ct-9466 194 4 a a DET ct-9466 194 5 , , PUNCT ct-9466 194 6 bostedt bostedt ADJ ct-9466 194 7 h h NOUN ct-9466 194 8 : : PUNCT ct-9466 194 9 follow follow VERB ct-9466 194 10 - - PUNCT ct-9466 194 11 up up ADP ct-9466 194 12 examinations examination NOUN ct-9466 194 13 of of ADP ct-9466 194 14 bitches bitch NOUN ct-9466 194 15 after after ADP ct-9466 194 16 conservative conservative ADJ ct-9466 194 17 treatment treatment NOUN ct-9466 194 18 of of ADP ct-9466 194 19 pyometra pyometra NOUN ct-9466 194 20 with with ADP ct-9466 194 21 the the DET ct-9466 194 22 antigestagen antigestagen NOUN ct-9466 194 23 aglepristone aglepristone ADJ ct-9466 194 24 . . PUNCT ct-9466 195 1 j j PROPN ct-9466 195 2 vet vet PROPN ct-9466 195 3 med med PROPN ct-9466 195 4 anat anat PROPN ct-9466 195 5 physiol physiol PROPN ct-9466 195 6 pathol pathol VERB ct-9466 195 7 clin clin PROPN ct-9466 195 8 med med PROPN ct-9466 195 9 2003;50:375 2003;50:375 PROPN ct-9466 195 10 - - SYM ct-9466 195 11 379 379 NUM ct-9466 195 12 . . PUNCT ct-9466 196 1 50 50 NUM ct-9466 196 2 . . PUNCT ct-9466 197 1 jurka jurka PROPN ct-9466 197 2 p p X ct-9466 197 3 , , PUNCT ct-9466 197 4 max max PROPN ct-9466 197 5 a a X ct-9466 197 6 , , PUNCT ct-9466 197 7 hawrynska hawrynska ADJ ct-9466 197 8 k k NOUN ct-9466 197 9 : : PUNCT ct-9466 197 10 age age NOUN ct-9466 197 11 related relate VERB ct-9466 197 12 pregnancy pregnancy NOUN ct-9466 197 13 results result NOUN ct-9466 197 14 and and CCONJ ct-9466 197 15 further further ADJ ct-9466 197 16 examination examination NOUN ct-9466 197 17 of of ADP ct-9466 197 18 bitches bitch NOUN ct-9466 197 19 after after ADP ct-9466 197 20 aglepristone aglepristone ADJ ct-9466 197 21 treatment treatment NOUN ct-9466 197 22 of of ADP ct-9466 197 23 pyometra pyometra NOUN ct-9466 197 24 . . PUNCT ct-9466 198 1 reprod reprod PROPN ct-9466 198 2 dom dom PROPN ct-9466 198 3 anim anim NOUN ct-9466 198 4 2010;45:525 2010;45:525 PROPN ct-9466 198 5 - - PUNCT ct-9466 198 6 529 529 NUM ct-9466 198 7 . . PUNCT ct-9466 199 1 51 51 NUM ct-9466 199 2 . . PUNCT ct-9466 200 1 nelson nelson PROPN ct-9466 200 2 rw rw PROPN ct-9466 200 3 , , PUNCT ct-9466 200 4 feldman feldman PROPN ct-9466 200 5 ec ec PROPN ct-9466 200 6 , , PUNCT ct-9466 200 7 stabenseld stabenseld PROPN ct-9466 200 8 gh gh PROPN ct-9466 200 9 : : PUNCT ct-9466 200 10 treatment treatment NOUN ct-9466 200 11 of of ADP ct-9466 200 12 canine canine NOUN ct-9466 200 13 pyometra pyometra NOUN ct-9466 200 14 and and CCONJ ct-9466 200 15 endometritis endometritis VERB ct-9466 200 16 by by ADP ct-9466 200 17 pgf2alpha pgf2alpha PROPN ct-9466 200 18 . . PROPN ct-9466 201 1 j j PROPN ct-9466 201 2 am be AUX ct-9466 201 3 vet vet NOUN ct-9466 201 4 med med ADJ ct-9466 201 5 assoc assoc PROPN ct-9466 201 6 1982;181:899 1982;181:899 PROPN ct-9466 201 7 - - SYM ct-9466 201 8 903 903 NUM ct-9466 201 9 . . PUNCT ct-9466 202 1 52 52 NUM ct-9466 202 2 . . X ct-9466 203 1 greer greer PROPN ct-9466 203 2 m m PROPN ct-9466 203 3 : : PUNCT ct-9466 203 4 canine canine NOUN ct-9466 203 5 reproduction reproduction NOUN ct-9466 203 6 and and CCONJ ct-9466 203 7 neonatology neonatology NOUN ct-9466 203 8 a a DET ct-9466 203 9 practical practical ADJ ct-9466 203 10 guide guide NOUN ct-9466 203 11 for for ADP ct-9466 203 12 veterinarians veterinarian NOUN ct-9466 203 13 , , PUNCT ct-9466 203 14 veterinary veterinary ADJ ct-9466 203 15 staff staff NOUN ct-9466 203 16 and and CCONJ ct-9466 203 17 breeders breeder NOUN ct-9466 203 18 . . PUNCT ct-9466 204 1 jackson jackson PROPN ct-9466 204 2 , , PUNCT ct-9466 204 3 wy wy PROPN ct-9466 204 4 ; ; PUNCT ct-9466 204 5 teton teton PROPN ct-9466 204 6 newmedia:2015 newmedia:2015 PROPN ct-9466 204 7 . . PUNCT ct-9466 205 1 53 53 NUM ct-9466 205 2 . . PUNCT ct-9466 206 1 lagerstedt lagerstedt PROPN ct-9466 206 2 as as ADP ct-9466 206 3 , , PUNCT ct-9466 206 4 obel obel PROPN ct-9466 206 5 n n CCONJ ct-9466 206 6 , , PUNCT ct-9466 206 7 stavenborn stavenborn PROPN ct-9466 206 8 m m NOUN ct-9466 206 9 : : PUNCT ct-9466 206 10 uterine uterine ADJ ct-9466 206 11 drainage drainage NOUN ct-9466 206 12 in in ADP ct-9466 206 13 the the DET ct-9466 206 14 bitch bitch NOUN ct-9466 206 15 for for ADP ct-9466 206 16 treatment treatment NOUN ct-9466 206 17 of of ADP ct-9466 206 18 pyometra pyometra ADJ ct-9466 206 19 refractory refractory NOUN ct-9466 206 20 to to ADP ct-9466 206 21 prostaglandin prostaglandin NOUN ct-9466 206 22 f2a f2a NOUN ct-9466 206 23 . . PUNCT ct-9466 207 1 j j PROPN ct-9466 207 2 small small PROPN ct-9466 207 3 anim anim PROPN ct-9466 207 4 pract pract NOUN ct-9466 207 5 1987;28:215 1987;28:215 PROPN ct-9466 207 6 - - NUM ct-9466 207 7 222 222 NUM ct-9466 207 8 . . PUNCT ct-9466 207 9 54 54 NUM ct-9466 207 10 . . PUNCT ct-9466 208 1 gurbulak gurbulak PROPN ct-9466 208 2 k k PROPN ct-9466 208 3 , , PUNCT ct-9466 208 4 pancarci pancarci PROPN ct-9466 208 5 m m PROPN ct-9466 208 6 , , PUNCT ct-9466 208 7 ekici ekici PROPN ct-9466 208 8 h h NOUN ct-9466 208 9 , , PUNCT ct-9466 208 10 et et PROPN ct-9466 208 11 al al PROPN ct-9466 208 12 : : PUNCT ct-9466 208 13 use use NOUN ct-9466 208 14 of of ADP ct-9466 208 15 aglepristone aglepristone ADJ ct-9466 208 16 and and CCONJ ct-9466 208 17 aglepristone aglepristone ADJ ct-9466 208 18 1 1 NUM ct-9466 208 19 intrauterine intrauterine ADJ ct-9466 208 20 antibiotic antibiotic NOUN ct-9466 208 21 for for ADP ct-9466 208 22 the the DET ct-9466 208 23 treatment treatment NOUN ct-9466 208 24 of of ADP ct-9466 208 25 pyometra pyometra NOUN ct-9466 208 26 in in ADP ct-9466 208 27 bitches bitch NOUN ct-9466 208 28 . . PUNCT ct-9466 209 1 acta acta PROPN ct-9466 209 2 vet vet PROPN ct-9466 209 3 hung hang VERB ct-9466 209 4 2005;53:249 2005;53:249 NOUN ct-9466 209 5 - - SYM ct-9466 209 6 255 255 NUM ct-9466 209 7 . . PUNCT ct-9466 210 1 55 55 NUM ct-9466 210 2 . . PUNCT ct-9466 211 1 gabor gabor PROPN ct-9466 211 2 g g PROPN ct-9466 211 3 , , PUNCT ct-9466 211 4 siver siver PROPN ct-9466 211 5 l l PROPN ct-9466 211 6 , , PUNCT ct-9466 211 7 szenci szenci PROPN ct-9466 211 8 o o NOUN ct-9466 211 9 : : PUNCT ct-9466 211 10 intravaginal intravaginal ADJ ct-9466 211 11 prostaglandin prostaglandin NOUN ct-9466 211 12 f2 f2 ADJ ct-9466 211 13 alpha alpha NOUN ct-9466 211 14 for for ADP ct-9466 211 15 the the DET ct-9466 211 16 treatment treatment NOUN ct-9466 211 17 of of ADP ct-9466 211 18 metritis metritis NOUN ct-9466 211 19 and and CCONJ ct-9466 211 20 pyometra pyometra NOUN ct-9466 211 21 in in ADP ct-9466 211 22 the the DET ct-9466 211 23 bitch bitch NOUN ct-9466 211 24 . . PUNCT ct-9466 212 1 acta acta PROPN ct-9466 212 2 vet vet PROPN ct-9466 212 3 hung hang VERB ct-9466 212 4 1999;47:103 1999;47:103 NOUN ct-9466 212 5 - - SYM ct-9466 212 6 108 108 NUM ct-9466 212 7 . . PUNCT ct-9466 213 1 56 56 NUM ct-9466 213 2 . . X ct-9466 213 3 de de PROPN ct-9466 213 4 cramer cramer PROPN ct-9466 213 5 kg kg PROPN ct-9466 213 6 : : PUNCT ct-9466 213 7 surgical surgical ADJ ct-9466 213 8 uterine uterine ADJ ct-9466 213 9 drainage drainage NOUN ct-9466 213 10 and and CCONJ ct-9466 213 11 lavage lavage NOUN ct-9466 213 12 as as ADP ct-9466 213 13 treatment treatment NOUN ct-9466 213 14 for for ADP ct-9466 213 15 canine canine NOUN ct-9466 213 16 pyometra pyometra NOUN ct-9466 213 17 . . PUNCT ct-9466 214 1 j j PROPN ct-9466 214 2 s s PROPN ct-9466 214 3 afr afr PROPN ct-9466 214 4 vet vet PROPN ct-9466 214 5 assoc assoc PROPN ct-9466 214 6 2010;81:172 2010;81:172 PROPN ct-9466 214 7 - - SYM ct-9466 214 8 177 177 NUM ct-9466 214 9 . . PUNCT ct-9466 215 1 57 57 NUM ct-9466 215 2 . . PUNCT ct-9466 216 1 kenney kenney PROPN ct-9466 216 2 kj kj PROPN ct-9466 216 3 , , PUNCT ct-9466 216 4 matthiesen matthiesen PROPN ct-9466 216 5 dt dt PROPN ct-9466 216 6 , , PUNCT ct-9466 216 7 brown brown ADJ ct-9466 216 8 no no INTJ ct-9466 216 9 , , PUNCT ct-9466 216 10 et et PROPN ct-9466 216 11 al al PROPN ct-9466 216 12 : : PUNCT ct-9466 216 13 pyometra pyometra NOUN ct-9466 216 14 in in ADP ct-9466 216 15 cats cat NOUN ct-9466 216 16 : : PUNCT ct-9466 216 17 183 183 NUM ct-9466 216 18 cases case NOUN ct-9466 216 19 ( ( PUNCT ct-9466 216 20 1979 1979 NUM ct-9466 216 21 - - SYM ct-9466 216 22 1984 1984 NUM ct-9466 216 23 ) ) PUNCT ct-9466 216 24 . . PUNCT ct-9466 217 1 j j PROPN ct-9466 217 2 am be AUX ct-9466 217 3 vet vet NOUN ct-9466 217 4 med med ADJ ct-9466 217 5 assoc assoc PROPN ct-9466 217 6 1987;191:1130 1987;191:1130 NUM ct-9466 217 7 - - SYM ct-9466 217 8 1132 1132 NUM ct-9466 217 9 . . PUNCT ct-9466 218 1 58 58 NUM ct-9466 218 2 . . PUNCT ct-9466 219 1 marretta marretta PROPN ct-9466 219 2 sm sm PROPN ct-9466 219 3 , , PUNCT ct-9466 219 4 matthiesen matthiesen PROPN ct-9466 219 5 dt dt PROPN ct-9466 219 6 , , PUNCT ct-9466 219 7 nichols nichols PROPN ct-9466 219 8 r r NOUN ct-9466 219 9 : : PUNCT ct-9466 219 10 pyometra pyometra NOUN ct-9466 219 11 and and CCONJ ct-9466 219 12 its its PRON ct-9466 219 13 complications complication NOUN ct-9466 219 14 . . PUNCT ct-9466 220 1 probl probl PROPN ct-9466 220 2 vet vet NOUN ct-9466 220 3 med me VERB ct-9466 220 4 1989;1:50 1989;1:50 PROPN ct-9466 220 5 - - PUNCT ct-9466 220 6 62 62 NUM ct-9466 220 7 . . PUNCT ct-9466 221 1 59 59 NUM ct-9466 221 2 . . PUNCT ct-9466 222 1 wheaton wheaton PROPN ct-9466 222 2 lg lg PROPN ct-9466 222 3 , , PUNCT ct-9466 222 4 johnson johnson PROPN ct-9466 222 5 al al PROPN ct-9466 222 6 , , PUNCT ct-9466 222 7 parker parker PROPN ct-9466 222 8 aj aj PROPN ct-9466 222 9 , , PUNCT ct-9466 222 10 et et PROPN ct-9466 222 11 al al PROPN ct-9466 222 12 : : PUNCT ct-9466 222 13 results result NOUN ct-9466 222 14 and and CCONJ ct-9466 222 15 complications complication NOUN ct-9466 222 16 of of ADP ct-9466 222 17 surgical surgical ADJ ct-9466 222 18 treatment treatment NOUN ct-9466 222 19 of of ADP ct-9466 222 20 pyometra pyometra NOUN ct-9466 222 21 : : PUNCT ct-9466 222 22 a a DET ct-9466 222 23 review review NOUN ct-9466 222 24 of of ADP ct-9466 222 25 80 80 NUM ct-9466 222 26 cases case NOUN ct-9466 222 27 . . PUNCT ct-9466 223 1 j j PROPN ct-9466 223 2 am be AUX ct-9466 223 3 anim anim PROPN ct-9466 223 4 hosp hosp PROPN ct-9466 223 5 assoc assoc PROPN ct-9466 223 6 1987;25:563 1987;25:563 PROPN ct-9466 223 7 - - SYM ct-9466 223 8 568 568 NUM ct-9466 223 9 . . PUNCT ct-9466 223 10 60 60 NUM ct-9466 223 11 . . PUNCT ct-9466 224 1 conti conti NOUN ct-9466 224 2 - - PROPN ct-9466 224 3 patara patara PROPN ct-9466 224 4 a a X ct-9466 224 5 , , PUNCT ct-9466 224 6 de de X ct-9466 224 7 araújo araújo PROPN ct-9466 224 8 caldeira caldeira PROPN ct-9466 224 9 j j PROPN ct-9466 224 10 , , PUNCT ct-9466 224 11 de de X ct-9466 224 12 mattos mattos NOUN ct-9466 224 13 - - PUNCT ct-9466 224 14 junior junior NOUN ct-9466 224 15 e e NOUN ct-9466 224 16 , , PUNCT ct-9466 224 17 et et PROPN ct-9466 224 18 al al PROPN ct-9466 224 19 : : PUNCT ct-9466 224 20 changes change NOUN ct-9466 224 21 in in ADP ct-9466 224 22 tissue tissue NOUN ct-9466 224 23 perfusion perfusion NOUN ct-9466 224 24 parameters parameter NOUN ct-9466 224 25 in in ADP ct-9466 224 26 dogs dog NOUN ct-9466 224 27 with with ADP ct-9466 224 28 severe severe ADJ ct-9466 224 29 sepsis sepsis NOUN ct-9466 224 30 / / SYM ct-9466 224 31 septic septic ADJ ct-9466 224 32 shock shock NOUN ct-9466 224 33 in in ADP ct-9466 224 34 response response NOUN ct-9466 224 35 to to ADP ct-9466 224 36 goal goal NOUN ct-9466 224 37 - - PUNCT ct-9466 224 38 directed direct VERB ct-9466 224 39 hemodynamic hemodynamic ADJ ct-9466 224 40 optimization optimization NOUN ct-9466 224 41 at at ADP ct-9466 224 42 admission admission NOUN ct-9466 224 43 to to ADP ct-9466 224 44 icu icu PROPN ct-9466 224 45 and and CCONJ ct-9466 224 46 the the DET ct-9466 224 47 relation relation NOUN ct-9466 224 48 to to PART ct-9466 224 49 outcome outcome VERB ct-9466 224 50 . . PUNCT ct-9466 225 1 j j PROPN ct-9466 225 2 vet vet PROPN ct-9466 225 3 emerg emerg PROPN ct-9466 225 4 crit crit PROPN ct-9466 225 5 care care PROPN ct-9466 225 6 2012;22:409 2012;22:409 NOUN ct-9466 225 7 - - SYM ct-9466 225 8 418 418 NUM ct-9466 225 9 . . PUNCT ct-9466 226 1 647 647 NUM ct-9466 226 2 clinical clinical ADJ ct-9466 226 3 theriogenology theriogenology NOUN ct-9466 226 4 • • NOUN ct-9466 226 5 volume volume NOUN ct-9466 226 6 11 11 NUM ct-9466 226 7 , , PUNCT ct-9466 226 8 number number NOUN ct-9466 226 9 4 4 NUM ct-9466 226 10 • • NOUN ct-9466 226 11 december december PROPN ct-9466 226 12 2019 2019 NUM ct-9466 226 13     SPACE ct-9466 226 14 61 61 NUM ct-9466 226 15 . . PUNCT ct-9466 227 1 heiene heiene ADJ ct-9466 227 2 r r NOUN ct-9466 227 3 , , PUNCT ct-9466 227 4 kristiansen kristiansen NOUN ct-9466 227 5 v v ADP ct-9466 227 6 , , PUNCT ct-9466 227 7 teige teige PROPN ct-9466 227 8 j j PROPN ct-9466 227 9 , , PUNCT ct-9466 227 10 et et PROPN ct-9466 227 11 al al PROPN ct-9466 227 12 : : PUNCT ct-9466 227 13 renal renal ADJ ct-9466 227 14 histomorphology histomorphology NOUN ct-9466 227 15 in in ADP ct-9466 227 16 dogs dog NOUN ct-9466 227 17 with with ADP ct-9466 227 18 pyometra pyometra ADJ ct-9466 227 19 and and CCONJ ct-9466 227 20 control control NOUN ct-9466 227 21 dogs dog NOUN ct-9466 227 22 , , PUNCT ct-9466 227 23 and and CCONJ ct-9466 227 24 long long ADJ ct-9466 227 25 - - PUNCT ct-9466 227 26 term term NOUN ct-9466 227 27 clinical clinical ADJ ct-9466 227 28 outcome outcome NOUN ct-9466 227 29 with with ADP ct-9466 227 30 respect respect NOUN ct-9466 227 31 to to ADP ct-9466 227 32 signs sign NOUN ct-9466 227 33 of of ADP ct-9466 227 34 kidney kidney NOUN ct-9466 227 35 disease disease NOUN ct-9466 227 36 . . PUNCT ct-9466 228 1 acta acta PROPN ct-9466 228 2 veterinaria veterinaria PROPN ct-9466 228 3 scandinavica scandinavica PROPN ct-9466 228 4 2007;49:13 2007;49:13 NUM ct-9466 228 5 . . PUNCT ct-9466 229 1 doi:10.1186/17510147 doi:10.1186/17510147 NOUN ct-9466 229 2 - - PUNCT ct-9466 229 3 49 49 NUM ct-9466 229 4 - - SYM ct-9466 229 5 13 13 NUM ct-9466 229 6 62 62 NUM ct-9466 229 7 . . PUNCT ct-9466 230 1 jena jena PROPN ct-9466 230 2 b b PROPN ct-9466 230 3 , , PUNCT ct-9466 230 4 rao rao PROPN ct-9466 230 5 ks ks PROPN ct-9466 230 6 , , PUNCT ct-9466 230 7 reddy reddy PROPN ct-9466 230 8 kcs kcs PROPN ct-9466 230 9 , , PUNCT ct-9466 230 10 et et PROPN ct-9466 230 11 al al PROPN ct-9466 230 12 : : PUNCT ct-9466 230 13 comparative comparative ADJ ct-9466 230 14 efficacy efficacy NOUN ct-9466 230 15 or or CCONJ ct-9466 230 16 various various ADJ ct-9466 230 17 therapeutic therapeutic ADJ ct-9466 230 18 protocols protocol NOUN ct-9466 230 19 in in ADP ct-9466 230 20 the the DET ct-9466 230 21 treatment treatment NOUN ct-9466 230 22 of of ADP ct-9466 230 23 pyometra pyometra NOUN ct-9466 230 24 in in ADP ct-9466 230 25 bitches bitch NOUN ct-9466 230 26 . . PUNCT ct-9466 231 1 vet vet NOUN ct-9466 231 2 med me VERB ct-9466 231 3 2013;58:271 2013;58:271 PROPN ct-9466 231 4 - - SYM ct-9466 231 5 276 276 NUM ct-9466 231 6 . . PUNCT ct-9466 232 1 63 63 NUM ct-9466 232 2 . . PUNCT ct-9466 233 1 contri contri PROPN ct-9466 233 2 a a PRON ct-9466 233 3 , , PUNCT ct-9466 233 4 gloria gloria PROPN ct-9466 233 5 a a NOUN ct-9466 233 6 , , PUNCT ct-9466 233 7 carluccio carluccio PROPN ct-9466 233 8 a a X ct-9466 233 9 , , PUNCT ct-9466 233 10 et et PROPN ct-9466 233 11 al al PROPN ct-9466 233 12 : : PUNCT ct-9466 233 13 effectiveness effectiveness NOUN ct-9466 233 14 of of ADP ct-9466 233 15 a a DET ct-9466 233 16 modified modified ADJ ct-9466 233 17 administration administration NOUN ct-9466 233 18 protocol protocol NOUN ct-9466 233 19 for for ADP ct-9466 233 20 the the DET ct-9466 233 21 medical medical ADJ ct-9466 233 22 treatment treatment NOUN ct-9466 233 23 of of ADP ct-9466 233 24 canine canine NOUN ct-9466 233 25 pyometra pyometra NOUN ct-9466 233 26 . . PUNCT ct-9466 234 1 vet vet NOUN ct-9466 234 2 res re NOUN ct-9466 234 3 commun commun PROPN ct-9466 234 4 2015;39:1 2015;39:1 PROPN ct-9466 234 5 - - PUNCT ct-9466 234 6 5 5 NUM ct-9466 234 7 . . NOUN ct-9466 234 8 64 64 NUM ct-9466 234 9 . . PUNCT ct-9466 235 1 gogny gogny NOUN ct-9466 235 2 a a PRON ct-9466 235 3 , , PUNCT ct-9466 235 4 fieni fieni ADJ ct-9466 235 5 f f NOUN ct-9466 235 6 : : PUNCT ct-9466 236 1 aglepristone aglepristone ADJ ct-9466 236 2 : : PUNCT ct-9466 236 3 a a DET ct-9466 236 4 review review NOUN ct-9466 236 5 on on ADP ct-9466 236 6 its its PRON ct-9466 236 7 clinical clinical ADJ ct-9466 236 8 use use NOUN ct-9466 236 9 in in ADP ct-9466 236 10 animals animal NOUN ct-9466 236 11 . . PUNCT ct-9466 237 1 theriogenology theriogenology NOUN ct-9466 237 2 2016;85:555 2016;85:555 PROPN ct-9466 237 3 - - SYM ct-9466 237 4 66 66 NUM ct-9466 237 5 . . PUNCT ct-9466 237 6 65 65 NUM ct-9466 237 7 . . PUNCT ct-9466 238 1 ros ros PROPN ct-9466 238 2 l l PROPN ct-9466 238 3 , , PUNCT ct-9466 238 4 holst holst NOUN ct-9466 238 5 bs bs PROPN ct-9466 238 6 , , PUNCT ct-9466 238 7 hagman hagman NOUN ct-9466 238 8 r r NOUN ct-9466 238 9 : : PUNCT ct-9466 238 10 a a DET ct-9466 238 11 retrospective retrospective ADJ ct-9466 238 12 study study NOUN ct-9466 238 13 of of ADP ct-9466 238 14 bitches bitch NOUN ct-9466 238 15 with with ADP ct-9466 238 16 pyometra pyometra NOUN ct-9466 238 17 , , PUNCT ct-9466 238 18 medically medically ADV ct-9466 238 19 treated treat VERB ct-9466 238 20 with with ADP ct-9466 238 21 aglepristone aglepristone NOUN ct-9466 238 22 . . PUNCT ct-9466 239 1 theriogenology theriogenology NOUN ct-9466 239 2 2014;82:1281 2014;82:1281 NUM ct-9466 239 3 - - SYM ct-9466 239 4 1286 1286 NUM ct-9466 239 5 . . PUNCT ct-9466 240 1 66 66 NUM ct-9466 240 2 . . PUNCT ct-9466 240 3 england england PROPN ct-9466 240 4 gc gc PROPN ct-9466 240 5 , , PUNCT ct-9466 240 6 freeman freeman PROPN ct-9466 240 7 sl sl PROPN ct-9466 240 8 , , PUNCT ct-9466 240 9 russo russo PROPN ct-9466 240 10 m m PROPN ct-9466 240 11 : : PUNCT ct-9466 240 12 treatment treatment NOUN ct-9466 240 13 of of ADP ct-9466 240 14 spontaneous spontaneous ADJ ct-9466 240 15 pyometra pyometra NOUN ct-9466 240 16 in in ADP ct-9466 240 17 22 22 NUM ct-9466 240 18 bitches bitch NOUN ct-9466 240 19 with with ADP ct-9466 240 20 a a DET ct-9466 240 21 combination combination NOUN ct-9466 240 22 of of ADP ct-9466 240 23 cabergoline cabergoline NOUN ct-9466 240 24 and and CCONJ ct-9466 240 25 cloprostenol cloprostenol NOUN ct-9466 240 26 . . PUNCT ct-9466 241 1 vet vet NOUN ct-9466 241 2 rec rec X ct-9466 241 3 2007;160:293 2007;160:293 NUM ct-9466 241 4 - - SYM ct-9466 241 5 296 296 NUM ct-9466 241 6 . . PUNCT ct-9466 241 7 67 67 NUM ct-9466 241 8 . . PUNCT ct-9466 242 1 corrada corrada PROPN ct-9466 242 2 y y PROPN ct-9466 242 3 , , PUNCT ct-9466 242 4 arias arias PROPN ct-9466 242 5 d d PROPN ct-9466 242 6 , , PUNCT ct-9466 242 7 rodriguez rodriguez NOUN ct-9466 242 8 r r NOUN ct-9466 242 9 , , PUNCT ct-9466 242 10 et et PROPN ct-9466 242 11 al al PROPN ct-9466 242 12 : : PUNCT ct-9466 242 13 combination combination NOUN ct-9466 242 14 dopamine dopamine NOUN ct-9466 242 15 agonist agonist NOUN ct-9466 242 16 and and CCONJ ct-9466 242 17 prostaglandin prostaglandin ADJ ct-9466 242 18 agonist agonist NOUN ct-9466 242 19 treatment treatment NOUN ct-9466 242 20 of of ADP ct-9466 242 21 cystic cystic ADJ ct-9466 242 22 endometrial endometrial ADJ ct-9466 242 23 hyperplasia hyperplasia NOUN ct-9466 242 24 - - PUNCT ct-9466 242 25 pyometra pyometra NOUN ct-9466 242 26 complex complex NOUN ct-9466 242 27 in in ADP ct-9466 242 28 the the DET ct-9466 242 29 bitch bitch NOUN ct-9466 242 30 . . PUNCT ct-9466 243 1 theriogenology theriogenology NOUN ct-9466 243 2 2006;66:1557 2006;66:1557 NUM ct-9466 243 3 - - SYM ct-9466 243 4 1559 1559 NUM ct-9466 243 5 . . PUNCT ct-9466 244 1 68 68 NUM ct-9466 244 2 . . PUNCT ct-9466 245 1 feldman feldman PROPN ct-9466 245 2 ec ec PROPN ct-9466 245 3 , , PUNCT ct-9466 245 4 nelson nelson PROPN ct-9466 245 5 rw rw PROPN ct-9466 245 6 : : PUNCT ct-9466 245 7 cystic cystic ADJ ct-9466 245 8 endometrial endometrial ADJ ct-9466 245 9 hyperplasia hyperplasia NOUN ct-9466 245 10 / / SYM ct-9466 245 11 pyometra pyometra NOUN ct-9466 245 12 complex complex NOUN ct-9466 245 13 . . PUNCT ct-9466 246 1 in in ADP ct-9466 246 2 : : PUNCT ct-9466 246 3 feldman feldman PROPN ct-9466 246 4 ec ec PROPN ct-9466 246 5 , , PUNCT ct-9466 246 6 nelson nelson PROPN ct-9466 246 7 rw rw PROPN ct-9466 246 8 , , PUNCT ct-9466 246 9 editors editor NOUN ct-9466 246 10 . . PUNCT ct-9466 247 1 endocrinology endocrinology NOUN ct-9466 247 2 and and CCONJ ct-9466 247 3 reproduction reproduction NOUN ct-9466 247 4 . . PUNCT ct-9466 248 1 3rd 3rd ADJ ct-9466 248 2 edition edition PROPN ct-9466 248 3 , , PUNCT ct-9466 248 4 st st PROPN ct-9466 248 5 louis louis PROPN ct-9466 248 6 , , PUNCT ct-9466 248 7 mo mo PROPN ct-9466 248 8 ; ; PUNCT ct-9466 248 9 saunders saunder NOUN ct-9466 248 10 : : PUNCT ct-9466 248 11 2004 2004 NUM ct-9466 248 12 . . PUNCT ct-9466 249 1 p. p. NOUN ct-9466 249 2 852 852 NUM ct-9466 249 3 - - SYM ct-9466 249 4 867 867 NUM ct-9466 249 5 . . PUNCT ct-9466 250 1 69 69 NUM ct-9466 250 2 . . PUNCT ct-9466 251 1 arnold arnold PROPN ct-9466 251 2 s s PROPN ct-9466 251 3 , , PUNCT ct-9466 251 4 hubler hubler PROPN ct-9466 251 5 m m PROPN ct-9466 251 6 , , PUNCT ct-9466 251 7 casal casal PROPN ct-9466 251 8 m m PROPN ct-9466 251 9 , , PUNCT ct-9466 251 10 et et PROPN ct-9466 251 11 al al PROPN ct-9466 251 12 : : PUNCT ct-9466 251 13 use use NOUN ct-9466 251 14 of of ADP ct-9466 251 15 low low ADJ ct-9466 251 16 dose dose NOUN ct-9466 251 17 prostaglandin prostaglandin NOUN ct-9466 251 18 for for ADP ct-9466 251 19 the the DET ct-9466 251 20 treatment treatment NOUN ct-9466 251 21 of of ADP ct-9466 251 22 canine canine NOUN ct-9466 251 23 pyometra pyometra NOUN ct-9466 251 24 . . PUNCT ct-9466 252 1 j j PROPN ct-9466 252 2 small small PROPN ct-9466 252 3 anim anim PROPN ct-9466 252 4 pract pract NOUN ct-9466 252 5 1988;29:303 1988;29:303 NUM ct-9466 252 6 - - SYM ct-9466 252 7 308 308 NUM ct-9466 252 8 . . PUNCT ct-9466 252 9 70 70 NUM ct-9466 252 10 . . PUNCT ct-9466 253 1 sridevi sridevi PROPN ct-9466 253 2 p p PROPN ct-9466 253 3 , , PUNCT ct-9466 253 4 balasubramanian balasubramanian PROPN ct-9466 253 5 s s PROPN ct-9466 253 6 , , PUNCT ct-9466 253 7 devanathan devanathan PROPN ct-9466 253 8 t t PROPN ct-9466 253 9 , , PUNCT ct-9466 253 10 et et PROPN ct-9466 253 11 al al PROPN ct-9466 253 12 : : PUNCT ct-9466 253 13 low low PROPN ct-9466 253 14 dose dose NOUN ct-9466 253 15 prostaglandin prostaglandin NOUN ct-9466 253 16 f2 f2 ADJ ct-9466 253 17 alpha alpha NOUN ct-9466 253 18 therapy therapy NOUN ct-9466 253 19 in in ADP ct-9466 253 20 treatment treatment NOUN ct-9466 253 21 of of ADP ct-9466 253 22 canine canine NOUN ct-9466 253 23 pyometra pyometra NOUN ct-9466 253 24 . . PUNCT ct-9466 254 1 indian indian PROPN ct-9466 254 2 vet vet PROPN ct-9466 254 3 j j PROPN ct-9466 254 4 2000;77:889 2000;77:889 PROPN ct-9466 254 5 - - PUNCT ct-9466 254 6 890 890 NUM ct-9466 254 7 . . PUNCT ct-9466 254 8 71 71 NUM ct-9466 254 9 . . PUNCT ct-9466 255 1 gobello gobello PROPN ct-9466 255 2 c c PROPN ct-9466 255 3 , , PUNCT ct-9466 255 4 castex castex NOUN ct-9466 255 5 g g PROPN ct-9466 255 6 , , PUNCT ct-9466 255 7 klima klima PROPN ct-9466 255 8 l l PROPN ct-9466 255 9 , , PUNCT ct-9466 255 10 et et PROPN ct-9466 255 11 al al PROPN ct-9466 255 12 : : PUNCT ct-9466 255 13 a a DET ct-9466 255 14 study study NOUN ct-9466 255 15 of of ADP ct-9466 255 16 two two NUM ct-9466 255 17 protocols protocol NOUN ct-9466 255 18 combing comb VERB ct-9466 255 19 aglepristone aglepristone ADJ ct-9466 255 20 and and CCONJ ct-9466 255 21 cloprostenol cloprostenol NOUN ct-9466 255 22 to to PART ct-9466 255 23 treat treat VERB ct-9466 255 24 open open ADJ ct-9466 255 25 cervix cervix NOUN ct-9466 255 26 pyometra pyometra NOUN ct-9466 255 27 in in ADP ct-9466 255 28 the the DET ct-9466 255 29 bitch bitch NOUN ct-9466 255 30 . . PUNCT ct-9466 256 1 theriogenology theriogenology NOUN ct-9466 256 2 2003;60:901 2003;60:901 NUM ct-9466 256 3 - - SYM ct-9466 256 4 908 908 NUM ct-9466 256 5 . . PUNCT ct-9466 257 1 72 72 NUM ct-9466 257 2 . . PUNCT ct-9466 258 1 karlsson karlsson PROPN ct-9466 258 2 i i PROPN ct-9466 258 3 , , PUNCT ct-9466 258 4 hagman hagman PROPN ct-9466 258 5 r r PROPN ct-9466 258 6 , , PUNCT ct-9466 258 7 johannisson johannisson NOUN ct-9466 258 8 a a NOUN ct-9466 258 9 , , PUNCT ct-9466 258 10 et et PROPN ct-9466 258 11 al al PROPN ct-9466 258 12 : : PUNCT ct-9466 258 13 multiplex multiplex PROPN ct-9466 258 14 cytokine cytokine NOUN ct-9466 258 15 analyses analyse VERB ct-9466 258 16 in in ADP ct-9466 258 17 dogs dog NOUN ct-9466 258 18 with with ADP ct-9466 258 19 pyometra pyometra NOUN ct-9466 258 20 suggest suggest VERB ct-9466 258 21 involvement involvement NOUN ct-9466 258 22 of of ADP ct-9466 258 23 kc kc PROPN ct-9466 258 24 - - PUNCT ct-9466 258 25 like like ADJ ct-9466 258 26 chemokine chemokine NOUN ct-9466 258 27 in in ADP ct-9466 258 28 canine canine NOUN ct-9466 258 29 bacterial bacterial ADJ ct-9466 258 30 sepsis sepsis NOUN ct-9466 258 31 . . PUNCT ct-9466 259 1 vet vet NOUN ct-9466 259 2 immunol immunol NOUN ct-9466 259 3 immunopathol immunopathol NOUN ct-9466 259 4 2016;170:41 2016;170:41 NUM ct-9466 259 5 - - SYM ct-9466 259 6 46 46 NUM ct-9466 259 7 . . PUNCT ct-9466 259 8 73 73 NUM ct-9466 259 9 . . PUNCT ct-9466 260 1 qian qian PROPN ct-9466 260 2 c c PROPN ct-9466 260 3 , , PUNCT ct-9466 260 4 hou hou PROPN ct-9466 260 5 j j PROPN ct-9466 260 6 : : PUNCT ct-9466 260 7 escherichia escherichia NOUN ct-9466 260 8 coli coli NOUN ct-9466 260 9 virulence virulence NOUN ct-9466 260 10 influences influence VERB ct-9466 260 11 the the DET ct-9466 260 12 roles role NOUN ct-9466 260 13 of of ADP ct-9466 260 14 sex sex NOUN ct-9466 260 15 hormone hormone NOUN ct-9466 260 16 receptors receptor NOUN ct-9466 260 17 in in ADP ct-9466 260 18 female female ADJ ct-9466 260 19 dogs dog NOUN ct-9466 260 20 with with ADP ct-9466 260 21 simulated simulated ADJ ct-9466 260 22 pyometra pyometra NOUN ct-9466 260 23 . . PUNCT ct-9466 261 1 exp exp NOUN ct-9466 261 2 therapeut therapeut NOUN ct-9466 261 3 med me VERB ct-9466 261 4 2017;14 2017;14 NOUN ct-9466 261 5 : : PUNCT ct-9466 261 6 3013 3013 NUM ct-9466 261 7 - - SYM ct-9466 261 8 3021 3021 NUM ct-9466 261 9 . . PUNCT ct-9466 262 1 74 74 NUM ct-9466 262 2 . . PUNCT ct-9466 263 1 davidson davidson PROPN ct-9466 263 2 a a DET ct-9466 263 3 : : PUNCT ct-9466 263 4 female female ADJ ct-9466 263 5 and and CCONJ ct-9466 263 6 male male ADJ ct-9466 263 7 infertility infertility NOUN ct-9466 263 8 and and CCONJ ct-9466 263 9 subfertility subfertility NOUN ct-9466 263 10 . . PUNCT ct-9466 264 1 in in ADP ct-9466 264 2 : : PUNCT ct-9466 264 3 nelson nelson PROPN ct-9466 264 4 rw rw PROPN ct-9466 264 5 , , PUNCT ct-9466 264 6 couto couto PROPN ct-9466 264 7 cg cg PROPN ct-9466 264 8 , , PUNCT ct-9466 264 9 editors editor NOUN ct-9466 264 10 . . PUNCT ct-9466 265 1 small small ADJ ct-9466 265 2 animal animal NOUN ct-9466 265 3 internal internal ADJ ct-9466 265 4 medicine medicine NOUN ct-9466 265 5 . . PUNCT ct-9466 266 1 5th 5th ADJ ct-9466 266 2 edition edition NOUN ct-9466 266 3 , , PUNCT ct-9466 266 4 st st PROPN ct-9466 266 5 louis louis PROPN ct-9466 266 6 , , PUNCT ct-9466 266 7 mo;elsevier mo;elsevier NOUN ct-9466 266 8 : : PUNCT ct-9466 266 9 2014 2014 NUM ct-9466 266 10 . . PUNCT ct-9466 267 1 p. p. NOUN ct-9466 267 2 951 951 NUM ct-9466 267 3 - - SYM ct-9466 267 4 965 965 NUM ct-9466 267 5 . . PUNCT ct-9466 268 1 75 75 NUM ct-9466 268 2 . . PUNCT ct-9466 269 1 burke burke PROPN ct-9466 269 2 tj tj PROPN ct-9466 269 3 : : PUNCT ct-9466 269 4 prostaglandin prostaglandin NOUN ct-9466 269 5 f2a f2a NOUN ct-9466 269 6 in in ADP ct-9466 269 7 treatment treatment NOUN ct-9466 269 8 of of ADP ct-9466 269 9 pyometra pyometra NOUN ct-9466 269 10 - - ADJ ct-9466 269 11 metritis metritis NOUN ct-9466 269 12 . . PUNCT ct-9466 270 1 vet vet NOUN ct-9466 270 2 clin clin PROPN ct-9466 270 3 north north PROPN ct-9466 270 4 am be AUX ct-9466 270 5 1982;12:107 1982;12:107 NOUN ct-9466 270 6 - - SYM ct-9466 270 7 109 109 NUM ct-9466 270 8 . . PUNCT ct-9466 271 1 648clinical 648clinical NUM ct-9466 271 2 theriogenology theriogenology NOUN ct-9466 271 3 • • NOUN ct-9466 271 4 volume volume NOUN ct-9466 271 5 11 11 NUM ct-9466 271 6 , , PUNCT ct-9466 271 7 number number NOUN ct-9466 271 8 4 4 NUM ct-9466 271 9 • • NOUN ct-9466 271 10 december december PROPN ct-9466 271 11 2019 2019 NUM ct-9466 271 12 untitled untitled ADJ