id	sid	tid	token	lemma	pos
cusj-10967	1	1	2024	2024	NUM
cusj-10967	1	2	manjila	manjila	PROPN
cusj-10967	1	3	,	,	PUNCT
cusj-10967	1	4	nihal	nihal	PROPN
cusj-10967	1	5	.	.	PUNCT
cusj-10967	2	1	this	this	PRON
cusj-10967	2	2	is	be	AUX
cusj-10967	2	3	an	an	DET
cusj-10967	2	4	open	open	ADJ
cusj-10967	2	5	-	-	PUNCT
cusj-10967	2	6	access	access	NOUN
cusj-10967	2	7	article	article	NOUN
cusj-10967	2	8	distributed	distribute	VERB
cusj-10967	2	9	under	under	ADP
cusj-10967	2	10	the	the	DET
cusj-10967	2	11	terms	term	NOUN
cusj-10967	2	12	of	of	ADP
cusj-10967	2	13	the	the	DET
cusj-10967	2	14	creative	creative	ADJ
cusj-10967	2	15	commons	common	NOUN
cusj-10967	2	16	attribution	attribution	NOUN
cusj-10967	2	17	license	license	NOUN
cusj-10967	2	18	,	,	PUNCT
cusj-10967	2	19	which	which	PRON
cusj-10967	2	20	permits	permit	VERB
cusj-10967	2	21	the	the	DET
cusj-10967	2	22	user	user	NOUN
cusj-10967	2	23	to	to	PART
cusj-10967	2	24	copy	copy	VERB
cusj-10967	2	25	,	,	PUNCT
cusj-10967	2	26	distribute	distribute	VERB
cusj-10967	2	27	,	,	PUNCT
cusj-10967	2	28	and	and	CCONJ
cusj-10967	2	29	transmit	transmit	VERB
cusj-10967	2	30	the	the	DET
cusj-10967	2	31	work	work	NOUN
cusj-10967	2	32	provided	provide	VERB
cusj-10967	2	33	that	that	SCONJ
cusj-10967	2	34	the	the	DET
cusj-10967	2	35	original	original	ADJ
cusj-10967	2	36	authors	author	NOUN
cusj-10967	2	37	and	and	CCONJ
cusj-10967	2	38	source	source	NOUN
cusj-10967	2	39	are	be	AUX
cusj-10967	2	40	credited	credit	VERB
cusj-10967	2	41	.	.	PUNCT
cusj-10967	3	1	recent	recent	ADJ
cusj-10967	3	2	progress	progress	NOUN
cusj-10967	3	3	in	in	ADP
cusj-10967	3	4	engineered	engineer	VERB
cusj-10967	3	5	oncolytic	oncolytic	ADJ
cusj-10967	3	6	viruses	virus	NOUN
cusj-10967	3	7	:	:	PUNCT
cusj-10967	3	8	a	a	DET
cusj-10967	3	9	thematic	thematic	ADJ
cusj-10967	3	10	review	review	NOUN
cusj-10967	3	11	nihal	nihal	PROPN
cusj-10967	3	12	manjila1	manjila1	NOUN
cusj-10967	3	13	1department	1department	NUM
cusj-10967	3	14	of	of	ADP
cusj-10967	3	15	biology	biology	NOUN
cusj-10967	3	16	,	,	PUNCT
cusj-10967	3	17	case	case	NOUN
cusj-10967	3	18	western	western	PROPN
cusj-10967	3	19	reserve	reserve	PROPN
cusj-10967	3	20	university	university	PROPN
cusj-10967	3	21	,	,	PUNCT
cusj-10967	3	22	cleveland	cleveland	PROPN
cusj-10967	3	23	,	,	PUNCT
cusj-10967	3	24	oh	oh	INTJ
cusj-10967	3	25	,	,	PUNCT
cusj-10967	3	26	usa	usa	PROPN
cusj-10967	3	27	keywords	keyword	NOUN
cusj-10967	3	28	:	:	PUNCT
cusj-10967	3	29	cancer	cancer	NOUN
cusj-10967	3	30	therapy	therapy	NOUN
cusj-10967	3	31	,	,	PUNCT
cusj-10967	3	32	oncolytic	oncolytic	ADJ
cusj-10967	3	33	viruses	virus	NOUN
cusj-10967	3	34	,	,	PUNCT
cusj-10967	3	35	medicine	medicine	NOUN
cusj-10967	3	36	,	,	PUNCT
cusj-10967	3	37	oncology	oncology	NOUN
cusj-10967	3	38	abstract	abstract	NOUN
cusj-10967	3	39	:	:	PUNCT
cusj-10967	3	40	this	this	DET
cusj-10967	3	41	review	review	NOUN
cusj-10967	3	42	examines	examine	VERB
cusj-10967	3	43	recent	recent	ADJ
cusj-10967	3	44	research	research	NOUN
cusj-10967	3	45	in	in	ADP
cusj-10967	3	46	engineered	engineer	VERB
cusj-10967	3	47	oncolytic	oncolytic	ADJ
cusj-10967	3	48	viruses	virus	NOUN
cusj-10967	3	49	and	and	CCONJ
cusj-10967	3	50	applies	apply	VERB
cusj-10967	3	51	a	a	DET
cusj-10967	3	52	thematic	thematic	ADJ
cusj-10967	3	53	analysis	analysis	NOUN
cusj-10967	3	54	to	to	PART
cusj-10967	3	55	identify	identify	VERB
cusj-10967	3	56	trends	trend	NOUN
cusj-10967	3	57	in	in	ADP
cusj-10967	3	58	the	the	DET
cusj-10967	3	59	field	field	NOUN
cusj-10967	3	60	.	.	PUNCT
cusj-10967	4	1	the	the	DET
cusj-10967	4	2	major	major	ADJ
cusj-10967	4	3	themes	theme	NOUN
cusj-10967	4	4	identified	identify	VERB
cusj-10967	4	5	are	be	AUX
cusj-10967	4	6	tumor	tumor	NOUN
cusj-10967	4	7	microenvironment	microenvironment	ADJ
cusj-10967	4	8	remodeling	remodeling	NOUN
cusj-10967	4	9	,	,	PUNCT
cusj-10967	4	10	enhancing	enhance	VERB
cusj-10967	4	11	virus	virus	NOUN
cusj-10967	4	12	efficiency	efficiency	NOUN
cusj-10967	4	13	,	,	PUNCT
cusj-10967	4	14	treating	treat	VERB
cusj-10967	4	15	slow	slow	ADV
cusj-10967	4	16	-	-	PUNCT
cusj-10967	4	17	growing	grow	VERB
cusj-10967	4	18	tumors	tumor	NOUN
cusj-10967	4	19	,	,	PUNCT
cusj-10967	4	20	tumor	tumor	NOUN
cusj-10967	4	21	targeting	target	VERB
cusj-10967	4	22	specificity	specificity	NOUN
cusj-10967	4	23	,	,	PUNCT
cusj-10967	4	24	and	and	CCONJ
cusj-10967	4	25	combination	combination	NOUN
cusj-10967	4	26	with	with	ADP
cusj-10967	4	27	chimeric	chimeric	ADJ
cusj-10967	4	28	antigen	antigen	ADJ
cusj-10967	4	29	receptor	receptor	NOUN
cusj-10967	4	30	-	-	PUNCT
cusj-10967	4	31	t	t	NOUN
cusj-10967	4	32	cell	cell	NOUN
cusj-10967	4	33	therapy	therapy	NOUN
cusj-10967	4	34	.	.	PUNCT
cusj-10967	5	1	the	the	DET
cusj-10967	5	2	tumor	tumor	NOUN
cusj-10967	5	3	microenvironment	microenvironment	NOUN
cusj-10967	5	4	plays	play	VERB
cusj-10967	5	5	a	a	DET
cusj-10967	5	6	significant	significant	ADJ
cusj-10967	5	7	role	role	NOUN
cusj-10967	5	8	in	in	ADP
cusj-10967	5	9	cancer	cancer	NOUN
cusj-10967	5	10	progression	progression	NOUN
cusj-10967	5	11	through	through	ADP
cusj-10967	5	12	factors	factor	NOUN
cusj-10967	5	13	like	like	ADP
cusj-10967	5	14	immunosuppression	immunosuppression	NOUN
cusj-10967	5	15	and	and	CCONJ
cusj-10967	5	16	hypoxia	hypoxia	NOUN
cusj-10967	5	17	.	.	PUNCT
cusj-10967	6	1	engineered	engineer	VERB
cusj-10967	6	2	oncolytic	oncolytic	ADJ
cusj-10967	6	3	viruses	virus	NOUN
cusj-10967	6	4	may	may	AUX
cusj-10967	6	5	be	be	AUX
cusj-10967	6	6	used	use	VERB
cusj-10967	6	7	to	to	PART
cusj-10967	6	8	remodel	remodel	VERB
cusj-10967	6	9	aspects	aspect	NOUN
cusj-10967	6	10	of	of	ADP
cusj-10967	6	11	the	the	DET
cusj-10967	6	12	tumor	tumor	NOUN
cusj-10967	6	13	microenvironment	microenvironment	NOUN
cusj-10967	6	14	to	to	PART
cusj-10967	6	15	favor	favor	VERB
cusj-10967	6	16	and	and	CCONJ
cusj-10967	6	17	facilitate	facilitate	VERB
cusj-10967	6	18	an	an	DET
cusj-10967	6	19	immune	immune	ADJ
cusj-10967	6	20	response	response	NOUN
cusj-10967	6	21	.	.	PUNCT
cusj-10967	7	1	another	another	DET
cusj-10967	7	2	major	major	ADJ
cusj-10967	7	3	consideration	consideration	NOUN
cusj-10967	7	4	in	in	ADP
cusj-10967	7	5	the	the	DET
cusj-10967	7	6	development	development	NOUN
cusj-10967	7	7	of	of	ADP
cusj-10967	7	8	oncolytic	oncolytic	ADJ
cusj-10967	7	9	viruses	virus	NOUN
cusj-10967	7	10	is	be	AUX
cusj-10967	7	11	their	their	PRON
cusj-10967	7	12	efficiency	efficiency	NOUN
cusj-10967	7	13	in	in	ADP
cusj-10967	7	14	inducing	induce	VERB
cusj-10967	7	15	antitumor	antitumor	PROPN
cusj-10967	7	16	effects	effect	NOUN
cusj-10967	7	17	.	.	PUNCT
cusj-10967	8	1	viral	viral	ADJ
cusj-10967	8	2	vectors	vector	NOUN
cusj-10967	8	3	may	may	AUX
cusj-10967	8	4	be	be	AUX
cusj-10967	8	5	engineered	engineer	VERB
cusj-10967	8	6	with	with	ADP
cusj-10967	8	7	pro	pro	ADJ
cusj-10967	8	8	-	-	ADJ
cusj-10967	8	9	apoptotic	apoptotic	ADJ
cusj-10967	8	10	or	or	CCONJ
cusj-10967	8	11	pro	pro	ADJ
cusj-10967	8	12	-	-	ADJ
cusj-10967	8	13	inflammatory	inflammatory	ADJ
cusj-10967	8	14	signaling	signal	VERB
cusj-10967	8	15	molecules	molecule	NOUN
cusj-10967	8	16	to	to	PART
cusj-10967	8	17	cause	cause	VERB
cusj-10967	8	18	cancer	cancer	NOUN
cusj-10967	8	19	cell	cell	NOUN
cusj-10967	8	20	death	death	NOUN
cusj-10967	8	21	or	or	CCONJ
cusj-10967	8	22	mediate	mediate	VERB
cusj-10967	8	23	immune	immune	ADJ
cusj-10967	8	24	cell	cell	NOUN
cusj-10967	8	25	infiltration	infiltration	NOUN
cusj-10967	8	26	,	,	PUNCT
cusj-10967	8	27	respectively	respectively	ADV
cusj-10967	8	28	.	.	PUNCT
cusj-10967	9	1	slow	slow	ADV
cusj-10967	9	2	-	-	PUNCT
cusj-10967	9	3	growing	grow	VERB
cusj-10967	9	4	tumors	tumor	NOUN
cusj-10967	9	5	present	present	VERB
cusj-10967	9	6	a	a	DET
cusj-10967	9	7	challenge	challenge	NOUN
cusj-10967	9	8	to	to	PART
cusj-10967	9	9	oncolytic	oncolytic	VERB
cusj-10967	9	10	virotherapy	virotherapy	NOUN
cusj-10967	9	11	since	since	SCONJ
cusj-10967	9	12	many	many	ADJ
cusj-10967	9	13	viruses	virus	NOUN
cusj-10967	9	14	infiltrate	infiltrate	VERB
cusj-10967	9	15	tumors	tumor	NOUN
cusj-10967	9	16	through	through	ADP
cusj-10967	9	17	infected	infected	ADJ
cusj-10967	9	18	daughter	daughter	NOUN
cusj-10967	9	19	cells	cell	NOUN
cusj-10967	9	20	arising	arise	VERB
cusj-10967	9	21	from	from	ADP
cusj-10967	9	22	cancer	cancer	NOUN
cusj-10967	9	23	cell	cell	NOUN
cusj-10967	9	24	division	division	NOUN
cusj-10967	9	25	.	.	PUNCT
cusj-10967	10	1	this	this	DET
cusj-10967	10	2	challenge	challenge	NOUN
cusj-10967	10	3	may	may	AUX
cusj-10967	10	4	be	be	AUX
cusj-10967	10	5	overcome	overcome	VERB
cusj-10967	10	6	by	by	ADP
cusj-10967	10	7	engineering	engineer	VERB
cusj-10967	10	8	viruses	virus	NOUN
cusj-10967	10	9	to	to	PART
cusj-10967	10	10	maintain	maintain	VERB
cusj-10967	10	11	a	a	DET
cusj-10967	10	12	high	high	ADJ
cusj-10967	10	13	viral	viral	ADJ
cusj-10967	10	14	load	load	NOUN
cusj-10967	10	15	in	in	ADP
cusj-10967	10	16	infected	infected	ADJ
cusj-10967	10	17	cancer	cancer	NOUN
cusj-10967	10	18	cells	cell	NOUN
cusj-10967	10	19	and	and	CCONJ
cusj-10967	10	20	drawing	draw	VERB
cusj-10967	10	21	a	a	DET
cusj-10967	10	22	sustained	sustained	ADJ
cusj-10967	10	23	immune	immune	ADJ
cusj-10967	10	24	response	response	NOUN
cusj-10967	10	25	.	.	PUNCT
cusj-10967	11	1	a	a	DET
cusj-10967	11	2	concern	concern	NOUN
cusj-10967	11	3	in	in	ADP
cusj-10967	11	4	the	the	DET
cusj-10967	11	5	development	development	NOUN
cusj-10967	11	6	of	of	ADP
cusj-10967	11	7	oncolytic	oncolytic	ADJ
cusj-10967	11	8	viruses	virus	NOUN
cusj-10967	11	9	is	be	AUX
cusj-10967	11	10	the	the	DET
cusj-10967	11	11	issue	issue	NOUN
cusj-10967	11	12	of	of	ADP
cusj-10967	11	13	viral	viral	ADJ
cusj-10967	11	14	tropism	tropism	NOUN
cusj-10967	11	15	and	and	CCONJ
cusj-10967	11	16	infection	infection	NOUN
cusj-10967	11	17	specificity	specificity	NOUN
cusj-10967	11	18	.	.	PUNCT
cusj-10967	12	1	although	although	SCONJ
cusj-10967	12	2	some	some	DET
cusj-10967	12	3	viruses	virus	NOUN
cusj-10967	12	4	have	have	AUX
cusj-10967	12	5	limited	limit	VERB
cusj-10967	12	6	tropism	tropism	NOUN
cusj-10967	12	7	,	,	PUNCT
cusj-10967	12	8	oncolytic	oncolytic	ADJ
cusj-10967	12	9	viruses	virus	NOUN
cusj-10967	12	10	may	may	AUX
cusj-10967	12	11	be	be	AUX
cusj-10967	12	12	engineered	engineer	VERB
cusj-10967	12	13	to	to	PART
cusj-10967	12	14	specifically	specifically	ADV
cusj-10967	12	15	target	target	VERB
cusj-10967	12	16	tumors	tumor	NOUN
cusj-10967	12	17	using	use	VERB
cusj-10967	12	18	cancer	cancer	NOUN
cusj-10967	12	19	-	-	PUNCT
cusj-10967	12	20	specific	specific	ADJ
cusj-10967	12	21	receptor	receptor	NOUN
cusj-10967	12	22	-	-	PUNCT
cusj-10967	12	23	ligand	ligand	NOUN
cusj-10967	12	24	mechanisms	mechanism	NOUN
cusj-10967	12	25	.	.	PUNCT
cusj-10967	13	1	oncolytic	oncolytic	ADJ
cusj-10967	13	2	viruses	virus	NOUN
cusj-10967	13	3	may	may	AUX
cusj-10967	13	4	also	also	ADV
cusj-10967	13	5	be	be	AUX
cusj-10967	13	6	used	use	VERB
cusj-10967	13	7	in	in	ADP
cusj-10967	13	8	conjunction	conjunction	NOUN
cusj-10967	13	9	with	with	ADP
cusj-10967	13	10	chimeric	chimeric	ADJ
cusj-10967	13	11	antigen	antigen	ADJ
cusj-10967	13	12	receptor	receptor	NOUN
cusj-10967	13	13	-	-	PUNCT
cusj-10967	13	14	t	t	NOUN
cusj-10967	13	15	cell	cell	NOUN
cusj-10967	13	16	therapy	therapy	NOUN
cusj-10967	13	17	to	to	PART
cusj-10967	13	18	reduce	reduce	VERB
cusj-10967	13	19	immunosuppression	immunosuppression	NOUN
cusj-10967	13	20	and	and	CCONJ
cusj-10967	13	21	enhance	enhance	VERB
cusj-10967	13	22	chimeric	chimeric	ADJ
cusj-10967	13	23	antigen	antigen	ADJ
cusj-10967	13	24	receptor	receptor	NOUN
cusj-10967	13	25	-	-	PUNCT
cusj-10967	13	26	t	t	NOUN
cusj-10967	13	27	cell	cell	NOUN
cusj-10967	13	28	infiltration	infiltration	NOUN
cusj-10967	13	29	of	of	ADP
cusj-10967	13	30	tumors	tumor	NOUN
cusj-10967	13	31	.	.	PUNCT
cusj-10967	14	1	this	this	PRON
cusj-10967	14	2	poses	pose	VERB
cusj-10967	14	3	a	a	DET
cusj-10967	14	4	promising	promising	ADJ
cusj-10967	14	5	approach	approach	NOUN
cusj-10967	14	6	in	in	ADP
cusj-10967	14	7	oncology	oncology	NOUN
cusj-10967	14	8	research	research	NOUN
cusj-10967	14	9	and	and	CCONJ
cusj-10967	14	10	treatment	treatment	NOUN
cusj-10967	14	11	.	.	PUNCT
cusj-10967	15	1	introduction	introduction	NOUN
cusj-10967	15	2	cancer	cancer	NOUN
cusj-10967	15	3	is	be	AUX
cusj-10967	15	4	a	a	DET
cusj-10967	15	5	class	class	NOUN
cusj-10967	15	6	of	of	ADP
cusj-10967	15	7	diseases	disease	NOUN
cusj-10967	15	8	characterized	characterize	VERB
cusj-10967	15	9	by	by	ADP
cusj-10967	15	10	the	the	DET
cusj-10967	15	11	uncontrolled	uncontrolled	ADJ
cusj-10967	15	12	proliferation	proliferation	NOUN
cusj-10967	15	13	of	of	ADP
cusj-10967	15	14	cells	cell	NOUN
cusj-10967	15	15	in	in	ADP
cusj-10967	15	16	the	the	DET
cusj-10967	15	17	body	body	NOUN
cusj-10967	15	18	.	.	PUNCT
cusj-10967	16	1	affecting	affect	VERB
cusj-10967	16	2	approximately	approximately	ADV
cusj-10967	16	3	20	20	NUM
cusj-10967	16	4	million	million	NUM
cusj-10967	16	5	people	people	NOUN
cusj-10967	16	6	globally	globally	ADV
cusj-10967	16	7	,	,	PUNCT
cusj-10967	16	8	cancer	cancer	NOUN
cusj-10967	16	9	has	have	VERB
cusj-10967	16	10	one	one	NUM
cusj-10967	16	11	of	of	ADP
cusj-10967	16	12	the	the	DET
cusj-10967	16	13	highest	high	ADJ
cusj-10967	16	14	mortality	mortality	NOUN
cusj-10967	16	15	rates	rate	NOUN
cusj-10967	16	16	with	with	ADP
cusj-10967	16	17	10	10	NUM
cusj-10967	16	18	million	million	NUM
cusj-10967	16	19	deaths	death	NOUN
cusj-10967	16	20	per	per	ADP
cusj-10967	16	21	year	year	NOUN
cusj-10967	16	22	,	,	PUNCT
cusj-10967	16	23	posing	pose	VERB
cusj-10967	16	24	as	as	ADP
cusj-10967	16	25	a	a	DET
cusj-10967	16	26	significant	significant	ADJ
cusj-10967	16	27	issue	issue	NOUN
cusj-10967	16	28	in	in	ADP
cusj-10967	16	29	the	the	DET
cusj-10967	16	30	medical	medical	ADJ
cusj-10967	16	31	field	field	NOUN
cusj-10967	16	32	.	.	PUNCT
cusj-10967	17	1	cancer	cancer	NOUN
cusj-10967	17	2	incidence	incidence	NOUN
cusj-10967	17	3	is	be	AUX
cusj-10967	17	4	exacerbated	exacerbate	VERB
cusj-10967	17	5	by	by	ADP
cusj-10967	17	6	the	the	DET
cusj-10967	17	7	lack	lack	NOUN
cusj-10967	17	8	of	of	ADP
cusj-10967	17	9	non	non	ADJ
cusj-10967	17	10	-	-	ADJ
cusj-10967	17	11	invasive	invasive	ADJ
cusj-10967	17	12	and	and	CCONJ
cusj-10967	17	13	side	side	ADJ
cusj-10967	17	14	effect	effect	NOUN
cusj-10967	17	15	-	-	PUNCT
cusj-10967	17	16	free	free	ADJ
cusj-10967	17	17	treatment	treatment	NOUN
cusj-10967	17	18	options	option	NOUN
cusj-10967	17	19	.	.	PUNCT
cusj-10967	18	1	while	while	SCONJ
cusj-10967	18	2	treatments	treatment	NOUN
cusj-10967	18	3	like	like	ADP
cusj-10967	18	4	chemotherapy	chemotherapy	NOUN
cusj-10967	18	5	may	may	AUX
cusj-10967	18	6	be	be	AUX
cusj-10967	18	7	effective	effective	ADJ
cusj-10967	18	8	at	at	ADP
cusj-10967	18	9	combating	combat	VERB
cusj-10967	18	10	cancer	cancer	NOUN
cusj-10967	18	11	,	,	PUNCT
cusj-10967	18	12	the	the	DET
cusj-10967	18	13	side	side	NOUN
cusj-10967	18	14	effects	effect	NOUN
cusj-10967	18	15	take	take	VERB
cusj-10967	18	16	a	a	DET
cusj-10967	18	17	toll	toll	NOUN
cusj-10967	18	18	on	on	ADP
cusj-10967	18	19	patients.1	patients.1	NOUN
cusj-10967	18	20	there	there	PRON
cusj-10967	18	21	are	be	VERB
cusj-10967	18	22	various	various	ADJ
cusj-10967	18	23	types	type	NOUN
cusj-10967	18	24	of	of	ADP
cusj-10967	18	25	cancer	cancer	NOUN
cusj-10967	18	26	,	,	PUNCT
cusj-10967	18	27	each	each	PRON
cusj-10967	18	28	with	with	ADP
cusj-10967	18	29	its	its	PRON
cusj-10967	18	30	own	own	ADJ
cusj-10967	18	31	genetic	genetic	ADJ
cusj-10967	18	32	causes	cause	NOUN
cusj-10967	18	33	and	and	CCONJ
cusj-10967	18	34	clinical	clinical	ADJ
cusj-10967	18	35	manifestations	manifestation	NOUN
cusj-10967	18	36	,	,	PUNCT
cusj-10967	18	37	which	which	PRON
cusj-10967	18	38	makes	make	VERB
cusj-10967	18	39	developing	develop	VERB
cusj-10967	18	40	treatments	treatment	NOUN
cusj-10967	18	41	more	more	ADV
cusj-10967	18	42	difficult	difficult	ADJ
cusj-10967	18	43	,	,	PUNCT
cusj-10967	18	44	as	as	SCONJ
cusj-10967	18	45	an	an	DET
cusj-10967	18	46	approach	approach	NOUN
cusj-10967	18	47	that	that	PRON
cusj-10967	18	48	is	be	AUX
cusj-10967	18	49	effective	effective	ADJ
cusj-10967	18	50	against	against	ADP
cusj-10967	18	51	one	one	NUM
cusj-10967	18	52	type	type	NOUN
cusj-10967	18	53	of	of	ADP
cusj-10967	18	54	cancer	cancer	NOUN
cusj-10967	18	55	may	may	AUX
cusj-10967	18	56	not	not	PART
cusj-10967	18	57	be	be	AUX
cusj-10967	18	58	effective	effective	ADJ
cusj-10967	18	59	against	against	ADP
cusj-10967	18	60	another	another	DET
cusj-10967	18	61	type	type	NOUN
cusj-10967	18	62	.	.	PUNCT
cusj-10967	19	1	for	for	ADP
cusj-10967	19	2	this	this	DET
cusj-10967	19	3	reason	reason	NOUN
cusj-10967	19	4	,	,	PUNCT
cusj-10967	19	5	more	more	ADJ
cusj-10967	19	6	therapeutics	therapeutic	NOUN
cusj-10967	19	7	for	for	ADP
cusj-10967	19	8	cancer	cancer	NOUN
cusj-10967	19	9	are	be	AUX
cusj-10967	19	10	vital	vital	ADJ
cusj-10967	19	11	.	.	PUNCT
cusj-10967	20	1	engineered	engineer	VERB
cusj-10967	20	2	oncolytic	oncolytic	ADJ
cusj-10967	20	3	viruses	virus	NOUN
cusj-10967	20	4	(	(	PUNCT
cusj-10967	20	5	ovs	ovs	NOUN
cusj-10967	20	6	)	)	PUNCT
cusj-10967	20	7	are	be	AUX
cusj-10967	20	8	viral	viral	ADJ
cusj-10967	20	9	vectors	vector	NOUN
cusj-10967	20	10	designed	design	VERB
cusj-10967	20	11	to	to	PART
cusj-10967	20	12	damage	damage	VERB
cusj-10967	20	13	and	and	CCONJ
cusj-10967	20	14	destroy	destroy	VERB
cusj-10967	20	15	cancer	cancer	NOUN
cusj-10967	20	16	cells	cell	NOUN
cusj-10967	20	17	.	.	PUNCT
cusj-10967	21	1	ovs	ovs	PROPN
cusj-10967	21	2	can	can	AUX
cusj-10967	21	3	be	be	AUX
cusj-10967	21	4	developed	develop	VERB
cusj-10967	21	5	using	use	VERB
cusj-10967	21	6	a	a	DET
cusj-10967	21	7	number	number	NOUN
cusj-10967	21	8	of	of	ADP
cusj-10967	21	9	different	different	ADJ
cusj-10967	21	10	theoretical	theoretical	ADJ
cusj-10967	21	11	approaches	approach	NOUN
cusj-10967	21	12	and	and	CCONJ
cusj-10967	21	13	experimental	experimental	ADJ
cusj-10967	21	14	modifications	modification	NOUN
cusj-10967	21	15	.	.	PUNCT
cusj-10967	22	1	once	once	ADV
cusj-10967	22	2	ovs	ovs	NOUN
cusj-10967	22	3	have	have	AUX
cusj-10967	22	4	been	be	AUX
cusj-10967	22	5	engineered	engineer	VERB
cusj-10967	22	6	and	and	CCONJ
cusj-10967	22	7	undergo	undergo	VERB
cusj-10967	22	8	basic	basic	ADJ
cusj-10967	22	9	testing	testing	NOUN
cusj-10967	22	10	,	,	PUNCT
cusj-10967	22	11	they	they	PRON
cusj-10967	22	12	can	can	AUX
cusj-10967	22	13	advance	advance	VERB
cusj-10967	22	14	to	to	ADP
cusj-10967	22	15	animal	animal	NOUN
cusj-10967	22	16	models	model	NOUN
cusj-10967	22	17	and	and	CCONJ
cusj-10967	22	18	clinical	clinical	ADJ
cusj-10967	22	19	trials	trial	NOUN
cusj-10967	22	20	.	.	PUNCT
cusj-10967	23	1	in	in	ADP
cusj-10967	23	2	the	the	DET
cusj-10967	23	3	past	past	ADJ
cusj-10967	23	4	five	five	NUM
cusj-10967	23	5	years	year	NOUN
cusj-10967	23	6	,	,	PUNCT
cusj-10967	23	7	there	there	PRON
cusj-10967	23	8	has	have	AUX
cusj-10967	23	9	been	be	AUX
cusj-10967	23	10	an	an	DET
cusj-10967	23	11	increasing	increase	VERB
cusj-10967	23	12	interest	interest	NOUN
cusj-10967	23	13	in	in	ADP
cusj-10967	23	14	ovs	ovs	NOUN
cusj-10967	23	15	due	due	ADP
cusj-10967	23	16	to	to	ADP
cusj-10967	23	17	the	the	DET
cusj-10967	23	18	treatment	treatment	NOUN
cusj-10967	23	19	method	method	NOUN
cusj-10967	23	20	’s	’s	PART
cusj-10967	23	21	novelty	novelty	NOUN
cusj-10967	23	22	and	and	CCONJ
cusj-10967	23	23	comparative	comparative	ADJ
cusj-10967	23	24	safety	safety	NOUN
cusj-10967	23	25	,	,	PUNCT
cusj-10967	23	26	which	which	PRON
cusj-10967	23	27	has	have	AUX
cusj-10967	23	28	led	lead	VERB
cusj-10967	23	29	researchers	researcher	NOUN
cusj-10967	23	30	to	to	PART
cusj-10967	23	31	perform	perform	VERB
cusj-10967	23	32	studies	study	NOUN
cusj-10967	23	33	taking	take	VERB
cusj-10967	23	34	different	different	ADJ
cusj-10967	23	35	approaches	approach	NOUN
cusj-10967	23	36	to	to	ADP
cusj-10967	23	37	advancing	advance	VERB
cusj-10967	23	38	the	the	DET
cusj-10967	23	39	knowledge	knowledge	NOUN
cusj-10967	23	40	and	and	CCONJ
cusj-10967	23	41	repertoire	repertoire	NOUN
cusj-10967	23	42	of	of	ADP
cusj-10967	23	43	effective	effective	ADJ
cusj-10967	23	44	ovs	ovs	NOUN
cusj-10967	23	45	for	for	ADP
cusj-10967	23	46	clinical	clinical	ADJ
cusj-10967	23	47	application.2	application.2	PROPN
cusj-10967	24	1	it	it	PRON
cusj-10967	24	2	is	be	AUX
cusj-10967	24	3	useful	useful	ADJ
cusj-10967	24	4	to	to	PART
cusj-10967	24	5	review	review	VERB
cusj-10967	24	6	recent	recent	ADJ
cusj-10967	24	7	advances	advance	NOUN
cusj-10967	24	8	in	in	ADP
cusj-10967	24	9	the	the	DET
cusj-10967	24	10	development	development	NOUN
cusj-10967	24	11	of	of	ADP
cusj-10967	24	12	engineered	engineer	VERB
cusj-10967	24	13	ovs	ovs	NOUN
cusj-10967	24	14	to	to	PART
cusj-10967	24	15	determine	determine	VERB
cusj-10967	24	16	contemporary	contemporary	ADJ
cusj-10967	24	17	research	research	NOUN
cusj-10967	24	18	trends	trend	NOUN
cusj-10967	24	19	.	.	PUNCT
cusj-10967	25	1	this	this	DET
cusj-10967	25	2	analysis	analysis	NOUN
cusj-10967	25	3	can	can	AUX
cusj-10967	25	4	be	be	AUX
cusj-10967	25	5	used	use	VERB
cusj-10967	25	6	columbia	columbia	PROPN
cusj-10967	25	7	undergraduate	undergraduate	PROPN
cusj-10967	25	8	science	science	PROPN
cusj-10967	25	9	journal	journal	PROPN
cusj-10967	25	10	vol	vol	NOUN
cusj-10967	25	11	.	.	PROPN
cusj-10967	26	1	18	18	NUM
cusj-10967	26	2	,	,	PUNCT
cusj-10967	26	3	2024	2024	NUM
cusj-10967	26	4	manjila	manjila	NOUN
cusj-10967	26	5	to	to	PART
cusj-10967	26	6	make	make	VERB
cusj-10967	26	7	predictions	prediction	NOUN
cusj-10967	26	8	about	about	ADP
cusj-10967	26	9	possible	possible	ADJ
cusj-10967	26	10	directions	direction	NOUN
cusj-10967	26	11	that	that	PRON
cusj-10967	26	12	ov	ov	VERB
cusj-10967	26	13	research	research	NOUN
cusj-10967	26	14	may	may	AUX
cusj-10967	26	15	take	take	VERB
cusj-10967	26	16	in	in	ADP
cusj-10967	26	17	the	the	DET
cusj-10967	26	18	future	future	NOUN
cusj-10967	26	19	.	.	PUNCT
cusj-10967	27	1	in	in	ADP
cusj-10967	27	2	this	this	DET
cusj-10967	27	3	review	review	NOUN
cusj-10967	27	4	,	,	PUNCT
cusj-10967	27	5	a	a	DET
cusj-10967	27	6	total	total	NOUN
cusj-10967	27	7	of	of	ADP
cusj-10967	27	8	42	42	NUM
cusj-10967	27	9	primary	primary	ADJ
cusj-10967	27	10	research	research	NOUN
cusj-10967	27	11	articles	article	NOUN
cusj-10967	27	12	were	be	AUX
cusj-10967	27	13	analyzed	analyze	VERB
cusj-10967	27	14	.	.	PUNCT
cusj-10967	28	1	the	the	DET
cusj-10967	28	2	majority	majority	NOUN
cusj-10967	28	3	of	of	ADP
cusj-10967	28	4	analyzed	analyze	VERB
cusj-10967	28	5	articles	article	NOUN
cusj-10967	28	6	involve	involve	VERB
cusj-10967	28	7	the	the	DET
cusj-10967	28	8	engineering	engineering	NOUN
cusj-10967	28	9	and	and	CCONJ
cusj-10967	28	10	testing	testing	NOUN
cusj-10967	28	11	of	of	ADP
cusj-10967	28	12	ovs	ovs	NOUN
cusj-10967	28	13	,	,	PUNCT
cusj-10967	28	14	but	but	CCONJ
cusj-10967	28	15	clinical	clinical	ADJ
cusj-10967	28	16	trials	trial	NOUN
cusj-10967	28	17	and	and	CCONJ
cusj-10967	28	18	theory	theory	NOUN
cusj-10967	28	19	papers	paper	NOUN
cusj-10967	28	20	are	be	AUX
cusj-10967	28	21	also	also	ADV
cusj-10967	28	22	included	include	VERB
cusj-10967	28	23	.	.	PUNCT
cusj-10967	29	1	among	among	ADP
cusj-10967	29	2	the	the	DET
cusj-10967	29	3	virus	virus	NOUN
cusj-10967	29	4	engineering	engineering	NOUN
cusj-10967	29	5	articles	article	NOUN
cusj-10967	29	6	,	,	PUNCT
cusj-10967	29	7	herpes	herpe	NOUN
cusj-10967	29	8	simplex	simplex	NOUN
cusj-10967	29	9	virus	virus	NOUN
cusj-10967	29	10	(	(	PUNCT
cusj-10967	29	11	hsv	hsv	PROPN
cusj-10967	29	12	)	)	PUNCT
cusj-10967	29	13	was	be	AUX
cusj-10967	29	14	the	the	DET
cusj-10967	29	15	most	most	ADV
cusj-10967	29	16	represented	represent	VERB
cusj-10967	29	17	(	(	PUNCT
cusj-10967	29	18	table	table	NOUN
cusj-10967	29	19	1	1	NUM
cusj-10967	29	20	)	)	PUNCT
cusj-10967	29	21	.	.	PUNCT
cusj-10967	30	1	this	this	PRON
cusj-10967	30	2	is	be	AUX
cusj-10967	30	3	due	due	ADJ
cusj-10967	30	4	to	to	ADP
cusj-10967	30	5	the	the	DET
cusj-10967	30	6	advantages	advantage	NOUN
cusj-10967	30	7	that	that	PRON
cusj-10967	30	8	hsv	hsv	PROPN
cusj-10967	30	9	possesses	possess	VERB
cusj-10967	30	10	as	as	ADP
cusj-10967	30	11	a	a	DET
cusj-10967	30	12	vector	vector	NOUN
cusj-10967	30	13	:	:	PUNCT
cusj-10967	30	14	it	it	PRON
cusj-10967	30	15	does	do	AUX
cusj-10967	30	16	not	not	PART
cusj-10967	30	17	integrate	integrate	VERB
cusj-10967	30	18	into	into	ADP
cusj-10967	30	19	the	the	DET
cusj-10967	30	20	host	host	NOUN
cusj-10967	30	21	genome	genome	NOUN
cusj-10967	30	22	since	since	SCONJ
cusj-10967	30	23	it	it	PRON
cusj-10967	30	24	is	be	AUX
cusj-10967	30	25	a	a	DET
cusj-10967	30	26	double	double	ADV
cusj-10967	30	27	-	-	PUNCT
cusj-10967	30	28	stranded	strand	VERB
cusj-10967	30	29	dna	dna	PROPN
cusj-10967	30	30	virus	virus	NOUN
cusj-10967	30	31	and	and	CCONJ
cusj-10967	30	32	possesses	possess	VERB
cusj-10967	30	33	a	a	DET
cusj-10967	30	34	large	large	ADJ
cusj-10967	30	35	genome	genome	NOUN
cusj-10967	30	36	that	that	PRON
cusj-10967	30	37	can	can	AUX
cusj-10967	30	38	serve	serve	VERB
cusj-10967	30	39	as	as	ADP
cusj-10967	30	40	a	a	DET
cusj-10967	30	41	stable	stable	ADJ
cusj-10967	30	42	base	base	NOUN
cusj-10967	30	43	for	for	ADP
cusj-10967	30	44	genetic	genetic	ADJ
cusj-10967	30	45	modifications	modification	NOUN
cusj-10967	30	46	.	.	PUNCT
cusj-10967	31	1	adenovirus	adenovirus	NOUN
cusj-10967	31	2	and	and	CCONJ
cusj-10967	31	3	vaccinia	vaccinia	NOUN
cusj-10967	31	4	virus	virus	NOUN
cusj-10967	31	5	were	be	AUX
cusj-10967	31	6	also	also	ADV
cusj-10967	31	7	well	well	ADV
cusj-10967	31	8	represented	represent	VERB
cusj-10967	31	9	,	,	PUNCT
cusj-10967	31	10	with	with	ADP
cusj-10967	31	11	approximately	approximately	ADV
cusj-10967	31	12	half	half	DET
cusj-10967	31	13	the	the	DET
cusj-10967	31	14	number	number	NOUN
cusj-10967	31	15	of	of	ADP
cusj-10967	31	16	articles	article	NOUN
cusj-10967	31	17	as	as	ADP
cusj-10967	31	18	herpes	herpe	NOUN
cusj-10967	31	19	simplex	simplex	NOUN
cusj-10967	31	20	virus	virus	NOUN
cusj-10967	31	21	.	.	PUNCT
cusj-10967	32	1	several	several	ADJ
cusj-10967	32	2	other	other	ADJ
cusj-10967	32	3	viruses	virus	NOUN
cusj-10967	32	4	were	be	AUX
cusj-10967	32	5	also	also	ADV
cusj-10967	32	6	utilized	utilize	VERB
cusj-10967	32	7	in	in	ADP
cusj-10967	32	8	the	the	DET
cusj-10967	32	9	analyzed	analyze	VERB
cusj-10967	32	10	studies	study	NOUN
cusj-10967	32	11	,	,	PUNCT
cusj-10967	32	12	including	include	VERB
cusj-10967	32	13	poliovirus	poliovirus	NOUN
cusj-10967	32	14	and	and	CCONJ
cusj-10967	32	15	bacteriophage	bacteriophage	NOUN
cusj-10967	32	16	t7	t7	PROPN
cusj-10967	32	17	.	.	PUNCT
cusj-10967	33	1	viral	viral	ADJ
cusj-10967	33	2	vector	vector	NOUN
cusj-10967	33	3	number	number	NOUN
cusj-10967	33	4	of	of	ADP
cusj-10967	33	5	studies	study	NOUN
cusj-10967	33	6	herpes	herpe	NOUN
cusj-10967	33	7	simplex	simplex	NOUN
cusj-10967	33	8	virus	virus	NOUN
cusj-10967	33	9	15	15	NUM
cusj-10967	33	10	adenovirus	adenovirus	NOUN
cusj-10967	33	11	9	9	NUM
cusj-10967	33	12	vaccinia	vaccinia	NOUN
cusj-10967	33	13	virus	virus	NOUN
cusj-10967	33	14	7	7	NUM
cusj-10967	33	15	vesicular	vesicular	ADJ
cusj-10967	33	16	stomatitis	stomatitis	NOUN
cusj-10967	33	17	virus	virus	NOUN
cusj-10967	33	18	3	3	NUM
cusj-10967	33	19	newcastle	newcastle	PROPN
cusj-10967	33	20	disease	disease	PROPN
cusj-10967	33	21	virus	virus	NOUN
cusj-10967	33	22	2	2	NUM
cusj-10967	33	23	reovirus	reovirus	NOUN
cusj-10967	33	24	1	1	NUM
cusj-10967	33	25	measles	measle	NOUN
cusj-10967	33	26	virus	virus	NOUN
cusj-10967	33	27	1	1	NUM
cusj-10967	33	28	zika	zika	X
cusj-10967	33	29	virus	virus	NOUN
cusj-10967	33	30	1	1	NUM
cusj-10967	33	31	maraba	maraba	NOUN
cusj-10967	33	32	virus	virus	NOUN
cusj-10967	33	33	1	1	NUM
cusj-10967	33	34	poliovirus	poliovirus	NOUN
cusj-10967	33	35	1	1	NUM
cusj-10967	33	36	myxovirus	myxovirus	NOUN
cusj-10967	33	37	1	1	NUM
cusj-10967	33	38	bacteriophage	bacteriophage	NOUN
cusj-10967	33	39	t7	t7	PROPN
cusj-10967	33	40	1	1	NUM
cusj-10967	33	41	*	*	NOUN
cusj-10967	33	42	a	a	DET
cusj-10967	33	43	number	number	NOUN
cusj-10967	33	44	of	of	ADP
cusj-10967	33	45	the	the	DET
cusj-10967	33	46	viruses	virus	NOUN
cusj-10967	33	47	counted	count	VERB
cusj-10967	33	48	were	be	AUX
cusj-10967	33	49	one	one	NUM
cusj-10967	33	50	of	of	ADP
cusj-10967	33	51	multiple	multiple	ADJ
cusj-10967	33	52	viruses	virus	NOUN
cusj-10967	33	53	used	use	VERB
cusj-10967	33	54	in	in	ADP
cusj-10967	33	55	a	a	DET
cusj-10967	33	56	single	single	ADJ
cusj-10967	33	57	study	study	NOUN
cusj-10967	33	58	.	.	PUNCT
cusj-10967	34	1	table	table	NOUN
cusj-10967	34	2	1	1	NUM
cusj-10967	34	3	.	.	PUNCT
cusj-10967	34	4	viral	viral	ADJ
cusj-10967	34	5	vectors	vector	NOUN
cusj-10967	34	6	represented	represent	VERB
cusj-10967	34	7	in	in	ADP
cusj-10967	34	8	analyzed	analyze	VERB
cusj-10967	34	9	studies	study	NOUN
cusj-10967	34	10	five	five	NUM
cusj-10967	34	11	major	major	ADJ
cusj-10967	34	12	themes	theme	NOUN
cusj-10967	34	13	or	or	CCONJ
cusj-10967	34	14	approaches	approach	NOUN
cusj-10967	34	15	were	be	AUX
cusj-10967	34	16	identified	identify	VERB
cusj-10967	34	17	in	in	ADP
cusj-10967	34	18	the	the	DET
cusj-10967	34	19	included	include	VERB
cusj-10967	34	20	studies	study	NOUN
cusj-10967	34	21	.	.	PUNCT
cusj-10967	35	1	first	first	ADV
cusj-10967	35	2	,	,	PUNCT
cusj-10967	35	3	remodeling	remodeling	NOUN
cusj-10967	35	4	of	of	ADP
cusj-10967	35	5	the	the	DET
cusj-10967	35	6	tumor	tumor	NOUN
cusj-10967	35	7	microenvironment	microenvironment	NOUN
cusj-10967	35	8	led	lead	VERB
cusj-10967	35	9	to	to	ADP
cusj-10967	35	10	improvement	improvement	NOUN
cusj-10967	35	11	in	in	ADP
cusj-10967	35	12	immune	immune	ADJ
cusj-10967	35	13	cell	cell	NOUN
cusj-10967	35	14	infiltration	infiltration	NOUN
cusj-10967	35	15	.	.	PUNCT
cusj-10967	36	1	this	this	DET
cusj-10967	36	2	approach	approach	NOUN
cusj-10967	36	3	allowed	allow	VERB
cusj-10967	36	4	the	the	DET
cusj-10967	36	5	immune	immune	ADJ
cusj-10967	36	6	system	system	NOUN
cusj-10967	36	7	to	to	PART
cusj-10967	36	8	target	target	VERB
cusj-10967	36	9	and	and	CCONJ
cusj-10967	36	10	destroy	destroy	VERB
cusj-10967	36	11	cancer	cancer	NOUN
cusj-10967	36	12	cells	cell	NOUN
cusj-10967	36	13	with	with	ADP
cusj-10967	36	14	its	its	PRON
cusj-10967	36	15	activated	activated	ADJ
cusj-10967	36	16	response	response	NOUN
cusj-10967	36	17	.	.	PUNCT
cusj-10967	37	1	second	second	ADJ
cusj-10967	37	2	,	,	PUNCT
cusj-10967	37	3	additional	additional	ADJ
cusj-10967	37	4	modification	modification	NOUN
cusj-10967	37	5	of	of	ADP
cusj-10967	37	6	engineered	engineer	VERB
cusj-10967	37	7	ovs	ovs	NOUN
cusj-10967	37	8	further	far	ADV
cusj-10967	37	9	improved	improve	VERB
cusj-10967	37	10	their	their	PRON
cusj-10967	37	11	antitumor	antitumor	PROPN
cusj-10967	37	12	effect	effect	NOUN
cusj-10967	37	13	.	.	PUNCT
cusj-10967	38	1	this	this	DET
cusj-10967	38	2	strategy	strategy	NOUN
cusj-10967	38	3	utilized	utilize	VERB
cusj-10967	38	4	the	the	DET
cusj-10967	38	5	variety	variety	NOUN
cusj-10967	38	6	of	of	ADP
cusj-10967	38	7	ovs	ovs	NOUN
cusj-10967	38	8	already	already	ADV
cusj-10967	38	9	designed	design	VERB
cusj-10967	38	10	by	by	ADP
cusj-10967	38	11	researchers	researcher	NOUN
cusj-10967	38	12	and	and	CCONJ
cusj-10967	38	13	advanced	advance	VERB
cusj-10967	38	14	their	their	PRON
cusj-10967	38	15	work	work	NOUN
cusj-10967	38	16	.	.	PUNCT
cusj-10967	39	1	third	third	ADJ
cusj-10967	39	2	,	,	PUNCT
cusj-10967	39	3	specialized	specialized	ADJ
cusj-10967	39	4	ovs	ovs	NOUN
cusj-10967	39	5	showed	show	VERB
cusj-10967	39	6	antitumor	antitumor	PROPN
cusj-10967	39	7	effects	effect	NOUN
cusj-10967	39	8	in	in	ADP
cusj-10967	39	9	the	the	DET
cusj-10967	39	10	treatment	treatment	NOUN
cusj-10967	39	11	of	of	ADP
cusj-10967	39	12	slow	slow	ADV
cusj-10967	39	13	-	-	PUNCT
cusj-10967	39	14	growing	grow	VERB
cusj-10967	39	15	tumors	tumor	NOUN
cusj-10967	39	16	.	.	PUNCT
cusj-10967	40	1	viral	viral	ADJ
cusj-10967	40	2	replication	replication	NOUN
cusj-10967	40	3	or	or	CCONJ
cusj-10967	40	4	antitumor	antitumor	NOUN
cusj-10967	40	5	effects	effect	NOUN
cusj-10967	40	6	that	that	PRON
cusj-10967	40	7	relied	rely	VERB
cusj-10967	40	8	on	on	ADP
cusj-10967	40	9	cancer	cancer	NOUN
cusj-10967	40	10	cell	cell	NOUN
cusj-10967	40	11	division	division	NOUN
cusj-10967	40	12	was	be	AUX
cusj-10967	40	13	ineffective	ineffective	ADJ
cusj-10967	40	14	in	in	ADP
cusj-10967	40	15	slowgrowing	slowgrowe	VERB
cusj-10967	40	16	tumors	tumor	NOUN
cusj-10967	40	17	.	.	PUNCT
cusj-10967	41	1	fourth	fourth	ADV
cusj-10967	41	2	,	,	PUNCT
cusj-10967	41	3	targeting	target	VERB
cusj-10967	41	4	of	of	ADP
cusj-10967	41	5	cancer	cancer	NOUN
cusj-10967	41	6	cells	cell	NOUN
cusj-10967	41	7	by	by	ADP
cusj-10967	41	8	viruses	virus	NOUN
cusj-10967	41	9	or	or	CCONJ
cusj-10967	41	10	immune	immune	ADJ
cusj-10967	41	11	cells	cell	NOUN
cusj-10967	41	12	were	be	AUX
cusj-10967	41	13	improved	improve	VERB
cusj-10967	41	14	using	use	VERB
cusj-10967	41	15	signaling	signal	VERB
cusj-10967	41	16	molecules	molecule	NOUN
cusj-10967	41	17	.	.	PUNCT
cusj-10967	42	1	increasing	increase	VERB
cusj-10967	42	2	infection	infection	NOUN
cusj-10967	42	3	specificity	specificity	NOUN
cusj-10967	42	4	improved	improve	VERB
cusj-10967	42	5	the	the	DET
cusj-10967	42	6	effectiveness	effectiveness	NOUN
cusj-10967	42	7	of	of	ADP
cusj-10967	42	8	ovs	ovs	NOUN
cusj-10967	42	9	,	,	PUNCT
cusj-10967	42	10	as	as	ADV
cusj-10967	42	11	well	well	ADV
cusj-10967	42	12	as	as	ADP
cusj-10967	42	13	reducing	reduce	VERB
cusj-10967	42	14	the	the	DET
cusj-10967	42	15	severity	severity	NOUN
cusj-10967	42	16	of	of	ADP
cusj-10967	42	17	potential	potential	ADJ
cusj-10967	42	18	side	side	NOUN
cusj-10967	42	19	effects	effect	NOUN
cusj-10967	42	20	.	.	PUNCT
cusj-10967	43	1	fifth	fifth	ADJ
cusj-10967	43	2	,	,	PUNCT
cusj-10967	43	3	oncolytic	oncolytic	ADJ
cusj-10967	43	4	virotherapy	virotherapy	NOUN
cusj-10967	43	5	in	in	ADP
cusj-10967	43	6	conjunction	conjunction	NOUN
cusj-10967	43	7	with	with	ADP
cusj-10967	43	8	chimeric	chimeric	ADJ
cusj-10967	43	9	antigen	antigen	ADJ
cusj-10967	43	10	receptor	receptor	NOUN
cusj-10967	43	11	-	-	PUNCT
cusj-10967	43	12	t	t	NOUN
cusj-10967	43	13	(	(	PUNCT
cusj-10967	43	14	car	car	NOUN
cusj-10967	43	15	-	-	PUNCT
cusj-10967	43	16	t	t	NOUN
cusj-10967	43	17	)	)	PUNCT
cusj-10967	43	18	cell	cell	NOUN
cusj-10967	43	19	therapy	therapy	NOUN
cusj-10967	43	20	shows	show	VERB
cusj-10967	43	21	improved	improve	VERB
cusj-10967	43	22	antitumor	antitumor	PROPN
cusj-10967	43	23	effectiveness	effectiveness	NOUN
cusj-10967	43	24	.	.	PUNCT
cusj-10967	44	1	the	the	DET
cusj-10967	44	2	theme	theme	NOUN
cusj-10967	44	3	of	of	ADP
cusj-10967	44	4	combinatorial	combinatorial	ADJ
cusj-10967	44	5	therapy	therapy	NOUN
cusj-10967	44	6	can	can	AUX
cusj-10967	44	7	be	be	AUX
cusj-10967	44	8	applied	apply	VERB
cusj-10967	44	9	to	to	ADP
cusj-10967	44	10	other	other	ADJ
cusj-10967	44	11	treatments	treatment	NOUN
cusj-10967	44	12	as	as	ADV
cusj-10967	44	13	well	well	ADV
cusj-10967	44	14	,	,	PUNCT
cusj-10967	44	15	with	with	ADP
cusj-10967	44	16	the	the	DET
cusj-10967	44	17	hope	hope	NOUN
cusj-10967	44	18	that	that	SCONJ
cusj-10967	44	19	the	the	DET
cusj-10967	44	20	anti	anti	ADJ
cusj-10967	44	21	-	-	ADJ
cusj-10967	44	22	tumor	tumor	ADJ
cusj-10967	44	23	effect	effect	NOUN
cusj-10967	44	24	will	will	AUX
cusj-10967	44	25	be	be	AUX
cusj-10967	44	26	greater	great	ADJ
cusj-10967	44	27	than	than	ADP
cusj-10967	44	28	either	either	DET
cusj-10967	44	29	treatment	treatment	NOUN
cusj-10967	44	30	alone	alone	ADV
cusj-10967	44	31	.	.	PUNCT
cusj-10967	45	1	tumor	tumor	NOUN
cusj-10967	45	2	microenvironment	microenvironment	ADJ
cusj-10967	45	3	remodeling	remodeling	NOUN
cusj-10967	45	4	:	:	PUNCT
cusj-10967	46	1	when	when	SCONJ
cusj-10967	46	2	cancer	cancer	NOUN
cusj-10967	46	3	cells	cell	NOUN
cusj-10967	46	4	accumulate	accumulate	VERB
cusj-10967	46	5	and	and	CCONJ
cusj-10967	46	6	form	form	NOUN
cusj-10967	46	7	tumors	tumor	NOUN
cusj-10967	46	8	,	,	PUNCT
cusj-10967	46	9	they	they	PRON
cusj-10967	46	10	create	create	VERB
cusj-10967	46	11	a	a	DET
cusj-10967	46	12	local	local	ADJ
cusj-10967	46	13	environment	environment	NOUN
cusj-10967	46	14	that	that	PRON
cusj-10967	46	15	decreases	decrease	VERB
cusj-10967	46	16	the	the	DET
cusj-10967	46	17	effectiveness	effectiveness	NOUN
cusj-10967	46	18	of	of	ADP
cusj-10967	46	19	the	the	DET
cusj-10967	46	20	immune	immune	ADJ
cusj-10967	46	21	system	system	NOUN
cusj-10967	46	22	in	in	ADP
cusj-10967	46	23	infiltrating	infiltrate	VERB
cusj-10967	46	24	the	the	DET
cusj-10967	46	25	tumor	tumor	NOUN
cusj-10967	46	26	and	and	CCONJ
cusj-10967	46	27	destroying	destroy	VERB
cusj-10967	46	28	the	the	DET
cusj-10967	46	29	cancer	cancer	NOUN
cusj-10967	46	30	cells.3	cells.3	VERB
cusj-10967	46	31	one	one	NUM
cusj-10967	46	32	of	of	ADP
cusj-10967	46	33	the	the	DET
cusj-10967	46	34	primary	primary	ADJ
cusj-10967	46	35	effects	effect	NOUN
cusj-10967	46	36	of	of	ADP
cusj-10967	46	37	this	this	DET
cusj-10967	46	38	tumor	tumor	NOUN
cusj-10967	46	39	microenvironment	microenvironment	NOUN
cusj-10967	46	40	is	be	AUX
cusj-10967	46	41	the	the	DET
cusj-10967	46	42	prevention	prevention	NOUN
cusj-10967	46	43	of	of	ADP
cusj-10967	46	44	natural	natural	ADJ
cusj-10967	46	45	killer	killer	NOUN
cusj-10967	46	46	(	(	PUNCT
cusj-10967	46	47	nk	nk	PROPN
cusj-10967	46	48	)	)	PUNCT
cusj-10967	46	49	cells	cell	NOUN
cusj-10967	46	50	from	from	ADP
cusj-10967	46	51	infiltrating	infiltrate	VERB
cusj-10967	46	52	the	the	DET
cusj-10967	46	53	tumor	tumor	NOUN
cusj-10967	46	54	mass	mass	PROPN
cusj-10967	46	55	.	.	PUNCT
cusj-10967	47	1	nk	nk	PROPN
cusj-10967	47	2	cells	cell	NOUN
cusj-10967	47	3	are	be	AUX
cusj-10967	47	4	one	one	NUM
cusj-10967	47	5	of	of	ADP
cusj-10967	47	6	the	the	DET
cusj-10967	47	7	immune	immune	ADJ
cusj-10967	47	8	system	system	NOUN
cusj-10967	47	9	’s	’s	PART
cusj-10967	47	10	major	major	ADJ
cusj-10967	47	11	cell	cell	NOUN
cusj-10967	47	12	types	type	NOUN
cusj-10967	47	13	,	,	PUNCT
cusj-10967	47	14	and	and	CCONJ
cusj-10967	47	15	they	they	PRON
cusj-10967	47	16	can	can	AUX
cusj-10967	47	17	target	target	VERB
cusj-10967	47	18	and	and	CCONJ
cusj-10967	47	19	destroy	destroy	VERB
cusj-10967	47	20	cancer	cancer	NOUN
cusj-10967	47	21	cells	cell	NOUN
cusj-10967	47	22	.	.	PUNCT
cusj-10967	48	1	in	in	ADP
cusj-10967	48	2	a	a	DET
cusj-10967	48	3	healthy	healthy	ADJ
cusj-10967	48	4	individual	individual	NOUN
cusj-10967	48	5	,	,	PUNCT
cusj-10967	48	6	nk	nk	PROPN
cusj-10967	48	7	cells	cell	NOUN
cusj-10967	48	8	will	will	AUX
cusj-10967	48	9	identify	identify	VERB
cusj-10967	48	10	and	and	CCONJ
cusj-10967	48	11	eliminate	eliminate	VERB
cusj-10967	48	12	any	any	DET
cusj-10967	48	13	abnormally	abnormally	ADV
cusj-10967	48	14	dividing	divide	VERB
cusj-10967	48	15	cells	cell	NOUN
cusj-10967	48	16	.	.	PUNCT
cusj-10967	49	1	in	in	ADP
cusj-10967	49	2	an	an	DET
cusj-10967	49	3	individual	individual	NOUN
cusj-10967	49	4	with	with	ADP
cusj-10967	49	5	cancer	cancer	NOUN
cusj-10967	49	6	,	,	PUNCT
cusj-10967	49	7	nk	nk	PROPN
cusj-10967	49	8	cells	cell	NOUN
cusj-10967	49	9	are	be	AUX
cusj-10967	49	10	unable	unable	ADJ
cusj-10967	49	11	to	to	PART
cusj-10967	49	12	overcome	overcome	VERB
cusj-10967	49	13	the	the	DET
cusj-10967	49	14	cancer	cancer	NOUN
cusj-10967	49	15	cells	cell	NOUN
cusj-10967	49	16	.	.	PUNCT
cusj-10967	50	1	other	other	ADJ
cusj-10967	50	2	components	component	NOUN
cusj-10967	50	3	of	of	ADP
cusj-10967	50	4	the	the	DET
cusj-10967	50	5	immune	immune	ADJ
cusj-10967	50	6	activity	activity	NOUN
cusj-10967	50	7	may	may	AUX
cusj-10967	50	8	also	also	ADV
cusj-10967	50	9	become	become	VERB
cusj-10967	50	10	inhibited	inhibited	ADJ
cusj-10967	50	11	,	,	PUNCT
cusj-10967	50	12	allowing	allow	VERB
cusj-10967	50	13	cancer	cancer	NOUN
cusj-10967	50	14	cells	cell	NOUN
cusj-10967	50	15	to	to	PART
cusj-10967	50	16	proliferate	proliferate	VERB
cusj-10967	50	17	and	and	CCONJ
cusj-10967	50	18	cause	cause	VERB
cusj-10967	50	19	metastasis	metastasis	NOUN
cusj-10967	50	20	.	.	PUNCT
cusj-10967	51	1	therefore	therefore	ADV
cusj-10967	51	2	,	,	PUNCT
cusj-10967	51	3	remodeling	remodeling	NOUN
cusj-10967	51	4	and	and	CCONJ
cusj-10967	51	5	modifying	modify	VERB
cusj-10967	51	6	the	the	DET
cusj-10967	51	7	tumor	tumor	NOUN
cusj-10967	51	8	microenvironment	microenvironment	NOUN
cusj-10967	51	9	to	to	PART
cusj-10967	51	10	facilitate	facilitate	VERB
cusj-10967	51	11	targeting	target	VERB
cusj-10967	51	12	of	of	ADP
cusj-10967	51	13	tumor	tumor	NOUN
cusj-10967	51	14	cells	cell	NOUN
cusj-10967	51	15	by	by	ADP
cusj-10967	51	16	nk	nk	PROPN
cusj-10967	51	17	cells	cell	NOUN
cusj-10967	51	18	could	could	AUX
cusj-10967	51	19	be	be	AUX
cusj-10967	51	20	a	a	DET
cusj-10967	51	21	design	design	NOUN
cusj-10967	51	22	goal	goal	NOUN
cusj-10967	51	23	for	for	ADP
cusj-10967	51	24	engineered	engineer	VERB
cusj-10967	51	25	ovs	ovs	NOUN
cusj-10967	51	26	.	.	PUNCT
cusj-10967	52	1	currently	currently	ADV
cusj-10967	52	2	,	,	PUNCT
cusj-10967	52	3	there	there	PRON
cusj-10967	52	4	is	be	VERB
cusj-10967	52	5	a	a	DET
cusj-10967	52	6	well	well	ADV
cusj-10967	52	7	-	-	PUNCT
cusj-10967	52	8	known	know	VERB
cusj-10967	52	9	engineered	engineer	VERB
cusj-10967	52	10	ov	ov	PROPN
cusj-10967	52	11	on	on	ADP
cusj-10967	52	12	the	the	DET
cusj-10967	52	13	market	market	NOUN
cusj-10967	52	14	known	know	VERB
cusj-10967	52	15	as	as	ADP
cusj-10967	52	16	talimogene	talimogene	ADJ
cusj-10967	52	17	laherparepvec	laherparepvec	PROPN
cusj-10967	52	18	(	(	PUNCT
cusj-10967	52	19	tvec	tvec	PROPN
cusj-10967	52	20	)	)	PUNCT
cusj-10967	52	21	,	,	PUNCT
cusj-10967	52	22	a	a	DET
cusj-10967	52	23	clinical	clinical	ADJ
cusj-10967	52	24	treatment	treatment	NOUN
cusj-10967	52	25	that	that	PRON
cusj-10967	52	26	utilizes	utilize	VERB
cusj-10967	52	27	an	an	DET
cusj-10967	52	28	engineered	engineer	VERB
cusj-10967	52	29	herpes	herpe	NOUN
cusj-10967	52	30	simplex	simplex	NOUN
cusj-10967	52	31	virus	virus	NOUN
cusj-10967	52	32	to	to	PART
cusj-10967	52	33	combat	combat	NOUN
cusj-10967	52	34	cancer	cancer	NOUN
cusj-10967	52	35	.	.	PUNCT
cusj-10967	53	1	it	it	PRON
cusj-10967	53	2	was	be	AUX
cusj-10967	53	3	thought	think	VERB
cusj-10967	53	4	that	that	SCONJ
cusj-10967	53	5	t	t	PROPN
cusj-10967	53	6	-	-	PUNCT
cusj-10967	53	7	vec	vec	PROPN
cusj-10967	53	8	columbia	columbia	PROPN
cusj-10967	53	9	undergraduate	undergraduate	PROPN
cusj-10967	53	10	science	science	PROPN
cusj-10967	53	11	journal	journal	PROPN
cusj-10967	53	12	vol	vol	NOUN
cusj-10967	53	13	.	.	PROPN
cusj-10967	53	14	18	18	NUM
cusj-10967	53	15	,	,	PUNCT
cusj-10967	53	16	2024	2024	NUM
cusj-10967	53	17	manjila	manjila	NOUN
cusj-10967	53	18	functioned	function	VERB
cusj-10967	53	19	through	through	ADP
cusj-10967	53	20	direct	direct	ADJ
cusj-10967	53	21	oncolysis	oncolysis	NOUN
cusj-10967	53	22	,	,	PUNCT
cusj-10967	53	23	or	or	CCONJ
cusj-10967	53	24	the	the	DET
cusj-10967	53	25	virus	virus	NOUN
cusj-10967	53	26	infecting	infect	VERB
cusj-10967	53	27	cancer	cancer	NOUN
cusj-10967	53	28	cells	cell	NOUN
cusj-10967	53	29	and	and	CCONJ
cusj-10967	53	30	causing	cause	VERB
cusj-10967	53	31	them	they	PRON
cusj-10967	53	32	to	to	PART
cusj-10967	53	33	die	die	VERB
cusj-10967	53	34	.	.	PUNCT
cusj-10967	54	1	ramelyte	ramelyte	NOUN
cusj-10967	54	2	and	and	CCONJ
cusj-10967	54	3	colleagues	colleague	NOUN
cusj-10967	54	4	showed	show	VERB
cusj-10967	54	5	that	that	SCONJ
cusj-10967	54	6	t	t	PROPN
cusj-10967	54	7	-	-	PUNCT
cusj-10967	54	8	vec	vec	PROPN
cusj-10967	54	9	does	do	AUX
cusj-10967	54	10	not	not	PART
cusj-10967	54	11	directly	directly	ADV
cusj-10967	54	12	cause	cause	VERB
cusj-10967	54	13	oncolysis	oncolysis	NOUN
cusj-10967	54	14	after	after	ADP
cusj-10967	54	15	conducting	conduct	VERB
cusj-10967	54	16	a	a	DET
cusj-10967	54	17	phase	phase	NOUN
cusj-10967	54	18	i	i	PRON
cusj-10967	54	19	clinical	clinical	ADJ
cusj-10967	54	20	trial	trial	NOUN
cusj-10967	54	21	of	of	ADP
cusj-10967	54	22	cutaneous	cutaneous	ADJ
cusj-10967	54	23	b	b	PROPN
cusj-10967	54	24	cell	cell	NOUN
cusj-10967	54	25	lymphoma	lymphoma	NOUN
cusj-10967	54	26	patients	patient	NOUN
cusj-10967	54	27	.	.	PUNCT
cusj-10967	55	1	instead	instead	ADV
cusj-10967	55	2	,	,	PUNCT
cusj-10967	55	3	research	research	NOUN
cusj-10967	55	4	found	find	VERB
cusj-10967	55	5	that	that	SCONJ
cusj-10967	55	6	the	the	DET
cusj-10967	55	7	treatment	treatment	NOUN
cusj-10967	55	8	alters	alter	VERB
cusj-10967	55	9	the	the	DET
cusj-10967	55	10	tumor	tumor	NOUN
cusj-10967	55	11	microenvironment	microenvironment	NOUN
cusj-10967	55	12	and	and	CCONJ
cusj-10967	55	13	allows	allow	VERB
cusj-10967	55	14	the	the	DET
cusj-10967	55	15	patient	patient	NOUN
cusj-10967	55	16	’s	’s	PART
cusj-10967	55	17	immune	immune	ADJ
cusj-10967	55	18	cells	cell	NOUN
cusj-10967	55	19	to	to	PART
cusj-10967	55	20	infiltrate	infiltrate	VERB
cusj-10967	55	21	and	and	CCONJ
cusj-10967	55	22	attack	attack	VERB
cusj-10967	55	23	the	the	DET
cusj-10967	55	24	tumor	tumor	NOUN
cusj-10967	55	25	.	.	PUNCT
cusj-10967	56	1	the	the	DET
cusj-10967	56	2	researchers	researcher	NOUN
cusj-10967	56	3	examined	examine	VERB
cusj-10967	56	4	tumor	tumor	NOUN
cusj-10967	56	5	appearance	appearance	NOUN
cusj-10967	56	6	,	,	PUNCT
cusj-10967	56	7	sequenced	sequence	VERB
cusj-10967	56	8	cell	cell	NOUN
cusj-10967	56	9	genetics	genetic	NOUN
cusj-10967	56	10	,	,	PUNCT
cusj-10967	56	11	and	and	CCONJ
cusj-10967	56	12	identified	identify	VERB
cusj-10967	56	13	immune	immune	ADJ
cusj-10967	56	14	cells	cell	NOUN
cusj-10967	56	15	present	present	ADJ
cusj-10967	56	16	in	in	ADP
cusj-10967	56	17	biopsy	biopsy	NOUN
cusj-10967	56	18	samples	sample	NOUN
cusj-10967	56	19	.	.	PUNCT
cusj-10967	57	1	they	they	PRON
cusj-10967	57	2	confirmed	confirm	VERB
cusj-10967	57	3	that	that	SCONJ
cusj-10967	57	4	the	the	DET
cusj-10967	57	5	treatment	treatment	NOUN
cusj-10967	57	6	reduced	reduce	VERB
cusj-10967	57	7	tumor	tumor	NOUN
cusj-10967	57	8	scope	scope	NOUN
cusj-10967	57	9	,	,	PUNCT
cusj-10967	57	10	both	both	CCONJ
cusj-10967	57	11	in	in	ADP
cusj-10967	57	12	the	the	DET
cusj-10967	57	13	tumor	tumor	NOUN
cusj-10967	57	14	at	at	ADP
cusj-10967	57	15	the	the	DET
cusj-10967	57	16	injection	injection	NOUN
cusj-10967	57	17	site	site	NOUN
cusj-10967	57	18	and	and	CCONJ
cusj-10967	57	19	in	in	ADP
cusj-10967	57	20	distant	distant	ADJ
cusj-10967	57	21	tumors	tumor	NOUN
cusj-10967	57	22	.	.	PUNCT
cusj-10967	58	1	they	they	PRON
cusj-10967	58	2	also	also	ADV
cusj-10967	58	3	found	find	VERB
cusj-10967	58	4	that	that	SCONJ
cusj-10967	58	5	multiple	multiple	ADJ
cusj-10967	58	6	types	type	NOUN
cusj-10967	58	7	of	of	ADP
cusj-10967	58	8	immune	immune	ADJ
cusj-10967	58	9	cells	cell	NOUN
cusj-10967	58	10	began	begin	VERB
cusj-10967	58	11	to	to	PART
cusj-10967	58	12	infiltrate	infiltrate	VERB
cusj-10967	58	13	the	the	DET
cusj-10967	58	14	primary	primary	ADJ
cusj-10967	58	15	tumor	tumor	NOUN
cusj-10967	58	16	as	as	SCONJ
cusj-10967	58	17	the	the	DET
cusj-10967	58	18	treatment	treatment	NOUN
cusj-10967	58	19	progressed	progress	VERB
cusj-10967	58	20	.	.	PUNCT
cusj-10967	59	1	lastly	lastly	ADV
cusj-10967	59	2	,	,	PUNCT
cusj-10967	59	3	they	they	PRON
cusj-10967	59	4	found	find	VERB
cusj-10967	59	5	that	that	SCONJ
cusj-10967	59	6	the	the	DET
cusj-10967	59	7	viral	viral	ADJ
cusj-10967	59	8	genetic	genetic	ADJ
cusj-10967	59	9	script	script	NOUN
cusj-10967	59	10	was	be	AUX
cusj-10967	59	11	present	present	ADJ
cusj-10967	59	12	in	in	ADP
cusj-10967	59	13	both	both	DET
cusj-10967	59	14	cancer	cancer	NOUN
cusj-10967	59	15	cells	cell	NOUN
cusj-10967	59	16	and	and	CCONJ
cusj-10967	59	17	healthy	healthy	ADJ
cusj-10967	59	18	cells	cell	NOUN
cusj-10967	59	19	,	,	PUNCT
cusj-10967	59	20	indicating	indicate	VERB
cusj-10967	59	21	a	a	DET
cusj-10967	59	22	nonspecific	nonspecific	ADJ
cusj-10967	59	23	infection	infection	NOUN
cusj-10967	59	24	mechanism.4	mechanism.4	NOUN
cusj-10967	59	25	these	these	DET
cusj-10967	59	26	findings	finding	NOUN
cusj-10967	59	27	provide	provide	VERB
cusj-10967	59	28	key	key	ADJ
cusj-10967	59	29	insights	insight	NOUN
cusj-10967	59	30	into	into	ADP
cusj-10967	59	31	the	the	DET
cusj-10967	59	32	significance	significance	NOUN
cusj-10967	59	33	of	of	ADP
cusj-10967	59	34	the	the	DET
cusj-10967	59	35	tumor	tumor	NOUN
cusj-10967	59	36	microenvironment	microenvironment	NOUN
cusj-10967	59	37	and	and	CCONJ
cusj-10967	59	38	viral	viral	ADJ
cusj-10967	59	39	design	design	NOUN
cusj-10967	59	40	in	in	ADP
cusj-10967	59	41	engineering	engineering	NOUN
cusj-10967	59	42	effective	effective	ADJ
cusj-10967	59	43	ovs	ovs	NOUN
cusj-10967	59	44	.	.	PUNCT
cusj-10967	60	1	ramelyte	ramelyte	NOUN
cusj-10967	60	2	and	and	CCONJ
cusj-10967	60	3	colleagues	colleague	NOUN
cusj-10967	60	4	demonstrated	demonstrate	VERB
cusj-10967	60	5	that	that	SCONJ
cusj-10967	60	6	it	it	PRON
cusj-10967	60	7	was	be	AUX
cusj-10967	60	8	not	not	PART
cusj-10967	60	9	necessary	necessary	ADJ
cusj-10967	60	10	for	for	SCONJ
cusj-10967	60	11	an	an	DET
cusj-10967	60	12	ov	ov	NOUN
cusj-10967	60	13	to	to	PART
cusj-10967	60	14	directly	directly	ADV
cusj-10967	60	15	destroy	destroy	VERB
cusj-10967	60	16	cancer	cancer	NOUN
cusj-10967	60	17	cells	cell	NOUN
cusj-10967	60	18	.	.	PUNCT
cusj-10967	61	1	instead	instead	ADV
cusj-10967	61	2	,	,	PUNCT
cusj-10967	61	3	the	the	DET
cusj-10967	61	4	ov	ov	PROPN
cusj-10967	61	5	could	could	AUX
cusj-10967	61	6	modify	modify	VERB
cusj-10967	61	7	the	the	DET
cusj-10967	61	8	tumor	tumor	NOUN
cusj-10967	61	9	microenvironment	microenvironment	NOUN
cusj-10967	61	10	and	and	CCONJ
cusj-10967	61	11	allow	allow	VERB
cusj-10967	61	12	the	the	DET
cusj-10967	61	13	immune	immune	ADJ
cusj-10967	61	14	response	response	NOUN
cusj-10967	61	15	to	to	PART
cusj-10967	61	16	take	take	VERB
cusj-10967	61	17	effect	effect	NOUN
cusj-10967	61	18	.	.	PUNCT
cusj-10967	62	1	this	this	PRON
cusj-10967	62	2	provides	provide	VERB
cusj-10967	62	3	a	a	DET
cusj-10967	62	4	mechanism	mechanism	NOUN
cusj-10967	62	5	for	for	ADP
cusj-10967	62	6	engineering	engineering	NOUN
cusj-10967	62	7	ovs	ovs	NOUN
cusj-10967	62	8	that	that	PRON
cusj-10967	62	9	would	would	AUX
cusj-10967	62	10	not	not	PART
cusj-10967	62	11	infect	infect	VERB
cusj-10967	62	12	healthy	healthy	ADJ
cusj-10967	62	13	cells	cell	NOUN
cusj-10967	62	14	to	to	ADP
cusj-10967	62	15	a	a	DET
cusj-10967	62	16	significant	significant	ADJ
cusj-10967	62	17	degree	degree	NOUN
cusj-10967	62	18	.	.	PUNCT
cusj-10967	63	1	one	one	NUM
cusj-10967	63	2	of	of	ADP
cusj-10967	63	3	the	the	DET
cusj-10967	63	4	major	major	ADJ
cusj-10967	63	5	strengths	strength	NOUN
cusj-10967	63	6	of	of	ADP
cusj-10967	63	7	ovs	ovs	NOUN
cusj-10967	63	8	and	and	CCONJ
cusj-10967	63	9	modification	modification	NOUN
cusj-10967	63	10	of	of	ADP
cusj-10967	63	11	the	the	DET
cusj-10967	63	12	tumor	tumor	NOUN
cusj-10967	63	13	microenvironment	microenvironment	NOUN
cusj-10967	63	14	is	be	AUX
cusj-10967	63	15	the	the	DET
cusj-10967	63	16	specificity	specificity	NOUN
cusj-10967	63	17	and	and	CCONJ
cusj-10967	63	18	efficacy	efficacy	NOUN
cusj-10967	63	19	that	that	PRON
cusj-10967	63	20	can	can	AUX
cusj-10967	63	21	be	be	AUX
cusj-10967	63	22	achieved	achieve	VERB
cusj-10967	63	23	relative	relative	ADJ
cusj-10967	63	24	to	to	ADP
cusj-10967	63	25	more	more	ADV
cusj-10967	63	26	traditional	traditional	ADJ
cusj-10967	63	27	treatment	treatment	NOUN
cusj-10967	63	28	approaches	approach	NOUN
cusj-10967	63	29	.	.	PUNCT
cusj-10967	64	1	additionally	additionally	ADV
cusj-10967	64	2	,	,	PUNCT
cusj-10967	64	3	the	the	DET
cusj-10967	64	4	tumor	tumor	NOUN
cusj-10967	64	5	microenvironment	microenvironment	NOUN
cusj-10967	64	6	contains	contain	VERB
cusj-10967	64	7	many	many	ADJ
cusj-10967	64	8	cell	cell	NOUN
cusj-10967	64	9	types	type	NOUN
cusj-10967	64	10	and	and	CCONJ
cusj-10967	64	11	active	active	ADJ
cusj-10967	64	12	pathways	pathway	NOUN
cusj-10967	64	13	that	that	PRON
cusj-10967	64	14	can	can	AUX
cusj-10967	64	15	be	be	AUX
cusj-10967	64	16	investigated	investigate	VERB
cusj-10967	64	17	and	and	CCONJ
cusj-10967	64	18	targeted	target	VERB
cusj-10967	64	19	by	by	ADP
cusj-10967	64	20	future	future	ADJ
cusj-10967	64	21	studies	study	NOUN
cusj-10967	64	22	,	,	PUNCT
cusj-10967	64	23	potentially	potentially	ADV
cusj-10967	64	24	showing	show	VERB
cusj-10967	64	25	anti	anti	ADJ
cusj-10967	64	26	-	-	ADJ
cusj-10967	64	27	tumor	tumor	ADJ
cusj-10967	64	28	effectiveness	effectiveness	NOUN
cusj-10967	64	29	that	that	PRON
cusj-10967	64	30	further	far	ADV
cusj-10967	64	31	improves	improve	VERB
cusj-10967	64	32	on	on	ADP
cusj-10967	64	33	preexisting	preexist	VERB
cusj-10967	64	34	ovs	ovs	NOUN
cusj-10967	64	35	or	or	CCONJ
cusj-10967	64	36	targets	target	VERB
cusj-10967	64	37	other	other	ADJ
cusj-10967	64	38	cancer	cancer	NOUN
cusj-10967	64	39	types	type	NOUN
cusj-10967	64	40	.	.	PUNCT
cusj-10967	65	1	the	the	DET
cusj-10967	65	2	microenvironment	microenvironment	ADJ
cusj-10967	65	3	remodeling	remodeling	NOUN
cusj-10967	65	4	approach	approach	NOUN
cusj-10967	65	5	has	have	AUX
cusj-10967	65	6	been	be	AUX
cusj-10967	65	7	utilized	utilize	VERB
cusj-10967	65	8	by	by	ADP
cusj-10967	65	9	a	a	DET
cusj-10967	65	10	number	number	NOUN
cusj-10967	65	11	of	of	ADP
cusj-10967	65	12	research	research	NOUN
cusj-10967	65	13	groups	group	NOUN
cusj-10967	65	14	addressing	address	VERB
cusj-10967	65	15	various	various	ADJ
cusj-10967	65	16	pathways	pathway	NOUN
cusj-10967	65	17	and	and	CCONJ
cusj-10967	65	18	cell	cell	NOUN
cusj-10967	65	19	types	type	NOUN
cusj-10967	65	20	present	present	ADJ
cusj-10967	65	21	in	in	ADP
cusj-10967	65	22	the	the	DET
cusj-10967	65	23	tumor	tumor	NOUN
cusj-10967	65	24	microenvironment	microenvironment	NOUN
cusj-10967	65	25	.	.	PUNCT
cusj-10967	66	1	cervera	cervera	NOUN
cusj-10967	66	2	-	-	PUNCT
cusj-10967	66	3	carrascon	carrascon	NOUN
cusj-10967	66	4	and	and	CCONJ
cusj-10967	66	5	colleagues	colleague	NOUN
cusj-10967	66	6	developed	develop	VERB
cusj-10967	66	7	an	an	DET
cusj-10967	66	8	oncolytic	oncolytic	ADJ
cusj-10967	66	9	adenovirus	adenovirus	NOUN
cusj-10967	66	10	that	that	PRON
cusj-10967	66	11	causes	cause	VERB
cusj-10967	66	12	infected	infect	VERB
cusj-10967	66	13	tumor	tumor	NOUN
cusj-10967	66	14	cells	cell	NOUN
cusj-10967	66	15	to	to	PART
cusj-10967	66	16	release	release	VERB
cusj-10967	66	17	two	two	NUM
cusj-10967	66	18	key	key	ADJ
cusj-10967	66	19	cytokines	cytokine	NOUN
cusj-10967	66	20	into	into	ADP
cusj-10967	66	21	the	the	DET
cusj-10967	66	22	tumor	tumor	NOUN
cusj-10967	66	23	microenvironment.5	microenvironment.5	PROPN
cusj-10967	67	1	the	the	DET
cusj-10967	67	2	cytokines	cytokine	NOUN
cusj-10967	67	3	signal	signal	VERB
cusj-10967	67	4	local	local	ADJ
cusj-10967	67	5	cytotoxic	cytotoxic	ADJ
cusj-10967	67	6	t	t	NOUN
cusj-10967	67	7	cells	cell	NOUN
cusj-10967	67	8	to	to	PART
cusj-10967	67	9	approach	approach	VERB
cusj-10967	67	10	and	and	CCONJ
cusj-10967	67	11	target	target	VERB
cusj-10967	67	12	the	the	DET
cusj-10967	67	13	tumor	tumor	NOUN
cusj-10967	67	14	.	.	PUNCT
cusj-10967	68	1	the	the	DET
cusj-10967	68	2	antitumor	antitumor	PROPN
cusj-10967	68	3	effectiveness	effectiveness	NOUN
cusj-10967	68	4	of	of	ADP
cusj-10967	68	5	the	the	DET
cusj-10967	68	6	adenovirus	adenovirus	NOUN
cusj-10967	68	7	is	be	AUX
cusj-10967	68	8	enhanced	enhance	VERB
cusj-10967	68	9	by	by	ADP
cusj-10967	68	10	the	the	DET
cusj-10967	68	11	addition	addition	NOUN
cusj-10967	68	12	of	of	ADP
cusj-10967	68	13	immune	immune	ADJ
cusj-10967	68	14	checkpoint	checkpoint	NOUN
cusj-10967	68	15	inhibitor	inhibitor	NOUN
cusj-10967	68	16	treatment	treatment	NOUN
cusj-10967	68	17	that	that	PRON
cusj-10967	68	18	activates	activate	VERB
cusj-10967	68	19	the	the	DET
cusj-10967	68	20	immune	immune	ADJ
cusj-10967	68	21	response	response	NOUN
cusj-10967	68	22	.	.	PUNCT
cusj-10967	69	1	lin	lin	PROPN
cusj-10967	69	2	and	and	CCONJ
cusj-10967	69	3	colleagues	colleague	NOUN
cusj-10967	69	4	engineered	engineer	VERB
cusj-10967	69	5	an	an	DET
cusj-10967	69	6	oncolytic	oncolytic	ADJ
cusj-10967	69	7	herpes	herpe	NOUN
cusj-10967	69	8	virus	virus	NOUN
cusj-10967	69	9	that	that	PRON
cusj-10967	69	10	releases	release	VERB
cusj-10967	69	11	damage	damage	NOUN
cusj-10967	69	12	-	-	PUNCT
cusj-10967	69	13	associated	associate	VERB
cusj-10967	69	14	signals	signal	NOUN
cusj-10967	69	15	to	to	PART
cusj-10967	69	16	facilitate	facilitate	VERB
cusj-10967	69	17	antigen	antigen	ADJ
cusj-10967	69	18	presentation	presentation	NOUN
cusj-10967	69	19	by	by	ADP
cusj-10967	69	20	dendritic	dendritic	ADJ
cusj-10967	69	21	cells	cell	NOUN
cusj-10967	69	22	and	and	CCONJ
cusj-10967	69	23	incite	incite	VERB
cusj-10967	69	24	an	an	DET
cusj-10967	69	25	immune	immune	ADJ
cusj-10967	69	26	response.6	response.6	NOUN
cusj-10967	69	27	rather	rather	ADV
cusj-10967	69	28	than	than	ADP
cusj-10967	69	29	counteracting	counteract	VERB
cusj-10967	69	30	immunosuppressive	immunosuppressive	ADJ
cusj-10967	69	31	signals	signal	NOUN
cusj-10967	69	32	,	,	PUNCT
cusj-10967	69	33	this	this	DET
cusj-10967	69	34	approach	approach	NOUN
cusj-10967	69	35	utilized	utilize	VERB
cusj-10967	69	36	antigen	antigen	DET
cusj-10967	69	37	presentation	presentation	NOUN
cusj-10967	69	38	to	to	PART
cusj-10967	69	39	incite	incite	VERB
cusj-10967	69	40	infiltration	infiltration	NOUN
cusj-10967	69	41	of	of	ADP
cusj-10967	69	42	the	the	DET
cusj-10967	69	43	tumor	tumor	NOUN
cusj-10967	69	44	by	by	ADP
cusj-10967	69	45	immune	immune	ADJ
cusj-10967	69	46	cells	cell	NOUN
cusj-10967	69	47	.	.	PUNCT
cusj-10967	70	1	gentile	gentile	NOUN
cusj-10967	70	2	and	and	CCONJ
cusj-10967	70	3	colleagues	colleague	NOUN
cusj-10967	70	4	created	create	VERB
cusj-10967	70	5	an	an	DET
cusj-10967	70	6	oncolytic	oncolytic	ADJ
cusj-10967	70	7	herpes	herpe	NOUN
cusj-10967	70	8	virus	virus	NOUN
cusj-10967	70	9	that	that	PRON
cusj-10967	70	10	causes	cause	VERB
cusj-10967	70	11	infected	infected	ADJ
cusj-10967	70	12	tumor	tumor	NOUN
cusj-10967	70	13	cells	cell	NOUN
cusj-10967	70	14	to	to	PART
cusj-10967	70	15	express	express	VERB
cusj-10967	70	16	adenosine	adenosine	ADJ
cusj-10967	70	17	deaminase	deaminase	NOUN
cusj-10967	70	18	,	,	PUNCT
cusj-10967	70	19	an	an	DET
cusj-10967	70	20	enzyme	enzyme	NOUN
cusj-10967	70	21	that	that	PRON
cusj-10967	70	22	breaks	break	VERB
cusj-10967	70	23	down	down	ADP
cusj-10967	70	24	extracellular	extracellular	ADJ
cusj-10967	70	25	adenosine	adenosine	NOUN
cusj-10967	70	26	—	—	PUNCT
cusj-10967	70	27	an	an	DET
cusj-10967	70	28	immunosuppressive	immunosuppressive	ADJ
cusj-10967	70	29	signaling	signal	VERB
cusj-10967	70	30	molecule.7	molecule.7	NOUN
cusj-10967	70	31	the	the	DET
cusj-10967	70	32	breakdown	breakdown	NOUN
cusj-10967	70	33	of	of	ADP
cusj-10967	70	34	adenosine	adenosine	NOUN
cusj-10967	70	35	in	in	ADP
cusj-10967	70	36	the	the	DET
cusj-10967	70	37	tumor	tumor	NOUN
cusj-10967	70	38	microenvironment	microenvironment	NOUN
cusj-10967	70	39	allows	allow	VERB
cusj-10967	70	40	local	local	ADJ
cusj-10967	70	41	immune	immune	ADJ
cusj-10967	70	42	cells	cell	NOUN
cusj-10967	70	43	to	to	PART
cusj-10967	70	44	become	become	VERB
cusj-10967	70	45	activated	activated	ADJ
cusj-10967	70	46	and	and	CCONJ
cusj-10967	70	47	attack	attack	VERB
cusj-10967	70	48	the	the	DET
cusj-10967	70	49	tumor	tumor	NOUN
cusj-10967	70	50	cells	cell	NOUN
cusj-10967	70	51	.	.	PUNCT
cusj-10967	71	1	keshavarz	keshavarz	PROPN
cusj-10967	71	2	and	and	CCONJ
cusj-10967	71	3	colleagues	colleague	NOUN
cusj-10967	71	4	developed	develop	VERB
cusj-10967	71	5	an	an	DET
cusj-10967	71	6	oncolytic	oncolytic	ADJ
cusj-10967	71	7	newcastle	newcastle	PROPN
cusj-10967	71	8	disease	disease	PROPN
cusj-10967	71	9	virus	virus	NOUN
cusj-10967	71	10	transported	transport	VERB
cusj-10967	71	11	by	by	ADP
cusj-10967	71	12	mesenchymal	mesenchymal	ADJ
cusj-10967	71	13	stem	stem	NOUN
cusj-10967	71	14	cells	cell	NOUN
cusj-10967	71	15	to	to	PART
cusj-10967	71	16	deliver	deliver	VERB
cusj-10967	71	17	apoptosis	apoptosis	NOUN
cusj-10967	71	18	signaling	signal	VERB
cusj-10967	71	19	molecules	molecule	NOUN
cusj-10967	71	20	to	to	ADP
cusj-10967	71	21	tumors.8	tumors.8	PROPN
cusj-10967	71	22	upon	upon	SCONJ
cusj-10967	71	23	binding	bind	VERB
cusj-10967	71	24	to	to	ADP
cusj-10967	71	25	the	the	DET
cusj-10967	71	26	appropriate	appropriate	ADJ
cusj-10967	71	27	receptors	receptor	NOUN
cusj-10967	71	28	in	in	ADP
cusj-10967	71	29	the	the	DET
cusj-10967	71	30	tumor	tumor	NOUN
cusj-10967	71	31	cells	cell	NOUN
cusj-10967	71	32	,	,	PUNCT
cusj-10967	71	33	the	the	DET
cusj-10967	71	34	apoptosis	apoptosis	NOUN
cusj-10967	71	35	signaling	signal	VERB
cusj-10967	71	36	molecules	molecule	NOUN
cusj-10967	71	37	will	will	AUX
cusj-10967	71	38	cause	cause	VERB
cusj-10967	71	39	the	the	DET
cusj-10967	71	40	cells	cell	NOUN
cusj-10967	71	41	to	to	PART
cusj-10967	71	42	undergo	undergo	VERB
cusj-10967	71	43	cell	cell	NOUN
cusj-10967	71	44	death	death	NOUN
cusj-10967	71	45	.	.	PUNCT
cusj-10967	72	1	each	each	PRON
cusj-10967	72	2	of	of	ADP
cusj-10967	72	3	these	these	DET
cusj-10967	72	4	studies	study	NOUN
cusj-10967	72	5	used	use	VERB
cusj-10967	72	6	biochemical	biochemical	ADJ
cusj-10967	72	7	pathways	pathway	NOUN
cusj-10967	72	8	as	as	ADP
cusj-10967	72	9	a	a	DET
cusj-10967	72	10	mechanism	mechanism	NOUN
cusj-10967	72	11	of	of	ADP
cusj-10967	72	12	action	action	NOUN
cusj-10967	72	13	for	for	ADP
cusj-10967	72	14	ovs	ovs	NOUN
cusj-10967	72	15	to	to	PART
cusj-10967	72	16	modify	modify	VERB
cusj-10967	72	17	the	the	DET
cusj-10967	72	18	signaling	signal	VERB
cusj-10967	72	19	molecule	molecule	NOUN
cusj-10967	72	20	repertoire	repertoire	NOUN
cusj-10967	72	21	present	present	NOUN
cusj-10967	72	22	in	in	ADP
cusj-10967	72	23	the	the	DET
cusj-10967	72	24	tumor	tumor	NOUN
cusj-10967	72	25	microenvironment	microenvironment	NOUN
cusj-10967	72	26	.	.	PUNCT
cusj-10967	73	1	other	other	ADJ
cusj-10967	73	2	researchers	researcher	NOUN
cusj-10967	73	3	have	have	AUX
cusj-10967	73	4	built	build	VERB
cusj-10967	73	5	on	on	ADP
cusj-10967	73	6	the	the	DET
cusj-10967	73	7	mechanism	mechanism	NOUN
cusj-10967	73	8	behind	behind	ADP
cusj-10967	73	9	tvec	tvec	PROPN
cusj-10967	73	10	’s	’s	PART
cusj-10967	73	11	function	function	NOUN
cusj-10967	73	12	,	,	PUNCT
cusj-10967	73	13	as	as	ADP
cusj-10967	73	14	in	in	ADP
cusj-10967	73	15	the	the	DET
cusj-10967	73	16	case	case	NOUN
cusj-10967	73	17	of	of	ADP
cusj-10967	73	18	the	the	DET
cusj-10967	73	19	oncolytic	oncolytic	ADJ
cusj-10967	73	20	herpes	herpe	NOUN
cusj-10967	73	21	virus	virus	NOUN
cusj-10967	73	22	engineered	engineer	VERB
cusj-10967	73	23	by	by	ADP
cusj-10967	73	24	haines	haine	NOUN
cusj-10967	73	25	and	and	CCONJ
cusj-10967	73	26	colleagues	colleague	NOUN
cusj-10967	73	27	to	to	PART
cusj-10967	73	28	not	not	PART
cusj-10967	73	29	infect	infect	VERB
cusj-10967	73	30	healthy	healthy	ADJ
cusj-10967	73	31	cells	cell	NOUN
cusj-10967	73	32	but	but	CCONJ
cusj-10967	73	33	still	still	ADV
cusj-10967	73	34	trigger	trigger	VERB
cusj-10967	73	35	immune	immune	ADJ
cusj-10967	73	36	recognition	recognition	NOUN
cusj-10967	73	37	of	of	ADP
cusj-10967	73	38	the	the	DET
cusj-10967	73	39	tumor.9	tumor.9	PROPN
cusj-10967	73	40	this	this	PRON
cusj-10967	73	41	is	be	AUX
cusj-10967	73	42	a	a	DET
cusj-10967	73	43	significant	significant	ADJ
cusj-10967	73	44	advance	advance	NOUN
cusj-10967	73	45	in	in	ADP
cusj-10967	73	46	ov	ov	PROPN
cusj-10967	73	47	engineering	engineering	NOUN
cusj-10967	73	48	as	as	SCONJ
cusj-10967	73	49	it	it	PRON
cusj-10967	73	50	improves	improve	VERB
cusj-10967	73	51	on	on	ADP
cusj-10967	73	52	a	a	DET
cusj-10967	73	53	virus	virus	NOUN
cusj-10967	73	54	in	in	ADP
cusj-10967	73	55	clinical	clinical	ADJ
cusj-10967	73	56	use	use	NOUN
cusj-10967	73	57	by	by	ADP
cusj-10967	73	58	increasing	increase	VERB
cusj-10967	73	59	infection	infection	NOUN
cusj-10967	73	60	specificity	specificity	NOUN
cusj-10967	73	61	.	.	PUNCT
cusj-10967	74	1	the	the	DET
cusj-10967	74	2	tumor	tumor	NOUN
cusj-10967	74	3	microenvironment	microenvironment	NOUN
cusj-10967	74	4	also	also	ADV
cusj-10967	74	5	includes	include	VERB
cusj-10967	74	6	several	several	ADJ
cusj-10967	74	7	cell	cell	NOUN
cusj-10967	74	8	types	type	NOUN
cusj-10967	74	9	that	that	PRON
cusj-10967	74	10	are	be	AUX
cusj-10967	74	11	normally	normally	ADV
cusj-10967	74	12	found	find	VERB
cusj-10967	74	13	in	in	ADP
cusj-10967	74	14	a	a	DET
cusj-10967	74	15	healthy	healthy	ADJ
cusj-10967	74	16	body	body	NOUN
cusj-10967	74	17	but	but	CCONJ
cusj-10967	74	18	may	may	AUX
cusj-10967	74	19	be	be	AUX
cusj-10967	74	20	present	present	ADJ
cusj-10967	74	21	within	within	ADP
cusj-10967	74	22	a	a	DET
cusj-10967	74	23	tumor	tumor	NOUN
cusj-10967	74	24	and	and	CCONJ
cusj-10967	74	25	closely	closely	ADV
cusj-10967	74	26	associated	associate	VERB
cusj-10967	74	27	with	with	ADP
cusj-10967	74	28	cancer	cancer	NOUN
cusj-10967	74	29	cells	cell	NOUN
cusj-10967	74	30	.	.	PUNCT
cusj-10967	75	1	kurisu	kurisu	PROPN
cusj-10967	75	2	and	and	CCONJ
cusj-10967	75	3	colleagues	colleague	NOUN
cusj-10967	75	4	used	use	VERB
cusj-10967	75	5	an	an	DET
cusj-10967	75	6	oncolytic	oncolytic	ADJ
cusj-10967	75	7	reovirus	reovirus	NOUN
cusj-10967	75	8	to	to	PART
cusj-10967	75	9	target	target	VERB
cusj-10967	75	10	and	and	CCONJ
cusj-10967	75	11	destroy	destroy	VERB
cusj-10967	75	12	columbia	columbia	PROPN
cusj-10967	75	13	undergraduate	undergraduate	PROPN
cusj-10967	75	14	science	science	PROPN
cusj-10967	75	15	journal	journal	PROPN
cusj-10967	75	16	vol	vol	NOUN
cusj-10967	75	17	.	.	PROPN
cusj-10967	75	18	18	18	NUM
cusj-10967	75	19	,	,	PUNCT
cusj-10967	75	20	2024	2024	NUM
cusj-10967	75	21	manjila	manjila	NOUN
cusj-10967	75	22	tumor	tumor	NOUN
cusj-10967	75	23	-	-	PUNCT
cusj-10967	75	24	associated	associate	VERB
cusj-10967	75	25	fibroblast	fibroblast	ADJ
cusj-10967	75	26	cells	cell	NOUN
cusj-10967	75	27	,	,	PUNCT
cusj-10967	75	28	which	which	PRON
cusj-10967	75	29	contribute	contribute	VERB
cusj-10967	75	30	to	to	ADP
cusj-10967	75	31	the	the	DET
cusj-10967	75	32	immunosuppressive	immunosuppressive	ADJ
cusj-10967	75	33	environment	environment	NOUN
cusj-10967	75	34	created	create	VERB
cusj-10967	75	35	by	by	ADP
cusj-10967	75	36	tumors.10	tumors.10	VERB
cusj-10967	75	37	the	the	DET
cusj-10967	75	38	researchers	researcher	NOUN
cusj-10967	75	39	also	also	ADV
cusj-10967	75	40	found	find	VERB
cusj-10967	75	41	that	that	SCONJ
cusj-10967	75	42	the	the	DET
cusj-10967	75	43	ov	ov	PROPN
cusj-10967	75	44	did	do	AUX
cusj-10967	75	45	not	not	PART
cusj-10967	75	46	harm	harm	VERB
cusj-10967	75	47	healthy	healthy	ADJ
cusj-10967	75	48	fibroblast	fibroblast	ADJ
cusj-10967	75	49	cells	cell	NOUN
cusj-10967	75	50	,	,	PUNCT
cusj-10967	75	51	indicating	indicate	VERB
cusj-10967	75	52	a	a	DET
cusj-10967	75	53	level	level	NOUN
cusj-10967	75	54	of	of	ADP
cusj-10967	75	55	infection	infection	NOUN
cusj-10967	75	56	specificity	specificity	NOUN
cusj-10967	75	57	.	.	PUNCT
cusj-10967	76	1	infection	infection	NOUN
cusj-10967	76	2	specificity	specificity	NOUN
cusj-10967	76	3	is	be	AUX
cusj-10967	76	4	important	important	ADJ
cusj-10967	76	5	in	in	ADP
cusj-10967	76	6	this	this	DET
cusj-10967	76	7	case	case	NOUN
cusj-10967	76	8	since	since	SCONJ
cusj-10967	76	9	the	the	DET
cusj-10967	76	10	ov	ov	PROPN
cusj-10967	76	11	directly	directly	ADV
cusj-10967	76	12	causes	cause	VERB
cusj-10967	76	13	fibroblasts	fibroblast	NOUN
cusj-10967	76	14	,	,	PUNCT
cusj-10967	76	15	a	a	DET
cusj-10967	76	16	cell	cell	NOUN
cusj-10967	76	17	type	type	NOUN
cusj-10967	76	18	that	that	PRON
cusj-10967	76	19	also	also	ADV
cusj-10967	76	20	naturally	naturally	ADV
cusj-10967	76	21	exists	exist	VERB
cusj-10967	76	22	in	in	ADP
cusj-10967	76	23	the	the	DET
cusj-10967	76	24	body	body	NOUN
cusj-10967	76	25	,	,	PUNCT
cusj-10967	76	26	to	to	ADP
cusj-10967	76	27	lyse	lyse	NOUN
cusj-10967	76	28	and	and	CCONJ
cusj-10967	76	29	die	die	VERB
cusj-10967	76	30	.	.	PUNCT
cusj-10967	77	1	however	however	ADV
cusj-10967	77	2	,	,	PUNCT
cusj-10967	77	3	it	it	PRON
cusj-10967	77	4	poses	pose	VERB
cusj-10967	77	5	potential	potential	ADJ
cusj-10967	77	6	risks	risk	NOUN
cusj-10967	77	7	and	and	CCONJ
cusj-10967	77	8	side	side	NOUN
cusj-10967	77	9	effects	effect	NOUN
cusj-10967	77	10	since	since	SCONJ
cusj-10967	77	11	an	an	DET
cusj-10967	77	12	ov	ov	NOUN
cusj-10967	77	13	with	with	ADP
cusj-10967	77	14	imprecise	imprecise	ADJ
cusj-10967	77	15	action	action	NOUN
cusj-10967	77	16	could	could	AUX
cusj-10967	77	17	destroy	destroy	VERB
cusj-10967	77	18	healthy	healthy	ADJ
cusj-10967	77	19	cell	cell	NOUN
cusj-10967	77	20	populations	population	NOUN
cusj-10967	77	21	.	.	PUNCT
cusj-10967	78	1	another	another	DET
cusj-10967	78	2	interesting	interesting	ADJ
cusj-10967	78	3	method	method	NOUN
cusj-10967	78	4	of	of	ADP
cusj-10967	78	5	approaching	approach	VERB
cusj-10967	78	6	tumor	tumor	NOUN
cusj-10967	78	7	microenvironment	microenvironment	NOUN
cusj-10967	78	8	remodeling	remodeling	NOUN
cusj-10967	78	9	is	be	AUX
cusj-10967	78	10	to	to	PART
cusj-10967	78	11	utilize	utilize	VERB
cusj-10967	78	12	a	a	DET
cusj-10967	78	13	viral	viral	ADJ
cusj-10967	78	14	vector	vector	NOUN
cusj-10967	78	15	that	that	PRON
cusj-10967	78	16	would	would	AUX
cusj-10967	78	17	not	not	PART
cusj-10967	78	18	normally	normally	ADV
cusj-10967	78	19	infect	infect	VERB
cusj-10967	78	20	human	human	ADJ
cusj-10967	78	21	cells	cell	NOUN
cusj-10967	78	22	.	.	PUNCT
cusj-10967	79	1	bacteriophages	bacteriophage	NOUN
cusj-10967	79	2	are	be	AUX
cusj-10967	79	3	viruses	virus	NOUN
cusj-10967	79	4	that	that	PRON
cusj-10967	79	5	infect	infect	VERB
cusj-10967	79	6	bacterial	bacterial	ADJ
cusj-10967	79	7	cells	cell	NOUN
cusj-10967	79	8	instead	instead	ADV
cusj-10967	79	9	of	of	ADP
cusj-10967	79	10	animal	animal	NOUN
cusj-10967	79	11	or	or	CCONJ
cusj-10967	79	12	plant	plant	NOUN
cusj-10967	79	13	cells	cell	NOUN
cusj-10967	79	14	.	.	PUNCT
cusj-10967	80	1	like	like	ADP
cusj-10967	80	2	other	other	ADJ
cusj-10967	80	3	classes	class	NOUN
cusj-10967	80	4	of	of	ADP
cusj-10967	80	5	viruses	virus	NOUN
cusj-10967	80	6	,	,	PUNCT
cusj-10967	80	7	bacteriophages	bacteriophage	NOUN
cusj-10967	80	8	can	can	AUX
cusj-10967	80	9	also	also	ADV
cusj-10967	80	10	be	be	AUX
cusj-10967	80	11	genetically	genetically	ADV
cusj-10967	80	12	and	and	CCONJ
cusj-10967	80	13	structurally	structurally	ADV
cusj-10967	80	14	engineered	engineer	VERB
cusj-10967	80	15	.	.	PUNCT
cusj-10967	81	1	the	the	DET
cusj-10967	81	2	challenge	challenge	NOUN
cusj-10967	81	3	of	of	ADP
cusj-10967	81	4	using	use	VERB
cusj-10967	81	5	a	a	DET
cusj-10967	81	6	bacteriophage	bacteriophage	NOUN
cusj-10967	81	7	as	as	ADP
cusj-10967	81	8	the	the	DET
cusj-10967	81	9	vector	vector	NOUN
cusj-10967	81	10	for	for	ADP
cusj-10967	81	11	ov	ov	ADP
cusj-10967	81	12	engineering	engineering	NOUN
cusj-10967	81	13	is	be	AUX
cusj-10967	81	14	that	that	SCONJ
cusj-10967	81	15	it	it	PRON
cusj-10967	81	16	does	do	AUX
cusj-10967	81	17	not	not	PART
cusj-10967	81	18	naturally	naturally	ADV
cusj-10967	81	19	infect	infect	VERB
cusj-10967	81	20	cancer	cancer	NOUN
cusj-10967	81	21	cells	cell	NOUN
cusj-10967	81	22	.	.	PUNCT
cusj-10967	82	1	instead	instead	ADV
cusj-10967	82	2	,	,	PUNCT
cusj-10967	82	3	they	they	PRON
cusj-10967	82	4	must	must	AUX
cusj-10967	82	5	be	be	AUX
cusj-10967	82	6	engineered	engineer	VERB
cusj-10967	82	7	to	to	PART
cusj-10967	82	8	target	target	VERB
cusj-10967	82	9	and	and	CCONJ
cusj-10967	82	10	infect	infect	VERB
cusj-10967	82	11	cancer	cancer	NOUN
cusj-10967	82	12	cells	cell	NOUN
cusj-10967	82	13	through	through	ADP
cusj-10967	82	14	signaling	signal	VERB
cusj-10967	82	15	or	or	CCONJ
cusj-10967	82	16	receptor	receptor	NOUN
cusj-10967	82	17	interactions	interaction	NOUN
cusj-10967	82	18	.	.	PUNCT
cusj-10967	83	1	hwang	hwang	PROPN
cusj-10967	83	2	and	and	CCONJ
cusj-10967	83	3	myung	myung	PROPN
cusj-10967	83	4	engineered	engineer	VERB
cusj-10967	83	5	bacteriophage	bacteriophage	NOUN
cusj-10967	83	6	t7	t7	PROPN
cusj-10967	83	7	to	to	PART
cusj-10967	83	8	express	express	VERB
cusj-10967	83	9	a	a	DET
cusj-10967	83	10	peptide	peptide	NOUN
cusj-10967	83	11	that	that	PRON
cusj-10967	83	12	contributes	contribute	VERB
cusj-10967	83	13	to	to	ADP
cusj-10967	83	14	tumor	tumor	NOUN
cusj-10967	83	15	growth	growth	NOUN
cusj-10967	83	16	inhibition	inhibition	NOUN
cusj-10967	83	17	and	and	CCONJ
cusj-10967	83	18	immune	immune	ADJ
cusj-10967	83	19	cell	cell	NOUN
cusj-10967	83	20	infiltration	infiltration	NOUN
cusj-10967	83	21	of	of	ADP
cusj-10967	83	22	tumors.11	tumors.11	NOUN
cusj-10967	83	23	this	this	DET
cusj-10967	83	24	result	result	NOUN
cusj-10967	83	25	indicates	indicate	VERB
cusj-10967	83	26	that	that	SCONJ
cusj-10967	83	27	bacteriophages	bacteriophage	NOUN
cusj-10967	83	28	are	be	AUX
cusj-10967	83	29	viable	viable	ADJ
cusj-10967	83	30	bases	basis	NOUN
cusj-10967	83	31	for	for	ADP
cusj-10967	83	32	ov	ov	ADP
cusj-10967	83	33	engineering	engineering	NOUN
cusj-10967	83	34	and	and	CCONJ
cusj-10967	83	35	that	that	SCONJ
cusj-10967	83	36	additional	additional	ADJ
cusj-10967	83	37	studies	study	NOUN
cusj-10967	83	38	could	could	AUX
cusj-10967	83	39	explore	explore	VERB
cusj-10967	83	40	this	this	DET
cusj-10967	83	41	class	class	NOUN
cusj-10967	83	42	of	of	ADP
cusj-10967	83	43	viruses	virus	NOUN
cusj-10967	83	44	.	.	PUNCT
cusj-10967	84	1	remodeling	remodeling	NOUN
cusj-10967	84	2	of	of	ADP
cusj-10967	84	3	the	the	DET
cusj-10967	84	4	tumor	tumor	NOUN
cusj-10967	84	5	microenvironment	microenvironment	NOUN
cusj-10967	84	6	holds	hold	VERB
cusj-10967	84	7	massive	massive	ADJ
cusj-10967	84	8	potential	potential	NOUN
cusj-10967	84	9	for	for	ADP
cusj-10967	84	10	engineered	engineer	VERB
cusj-10967	84	11	ov	ov	PROPN
cusj-10967	84	12	research	research	NOUN
cusj-10967	84	13	.	.	PUNCT
cusj-10967	85	1	t	t	PROPN
cusj-10967	85	2	-	-	PUNCT
cusj-10967	85	3	vec	vec	PROPN
cusj-10967	85	4	has	have	AUX
cusj-10967	85	5	already	already	ADV
cusj-10967	85	6	been	be	AUX
cusj-10967	85	7	implemented	implement	VERB
cusj-10967	85	8	as	as	ADP
cusj-10967	85	9	a	a	DET
cusj-10967	85	10	clinical	clinical	ADJ
cusj-10967	85	11	treatment	treatment	NOUN
cusj-10967	85	12	and	and	CCONJ
cusj-10967	85	13	has	have	AUX
cusj-10967	85	14	shown	show	VERB
cusj-10967	85	15	success	success	NOUN
cusj-10967	85	16	in	in	ADP
cusj-10967	85	17	the	the	DET
cusj-10967	85	18	clinical	clinical	ADJ
cusj-10967	85	19	setting	setting	NOUN
cusj-10967	85	20	.	.	PUNCT
cusj-10967	86	1	microenvironment	microenvironment	ADJ
cusj-10967	86	2	remodeling	remodeling	NOUN
cusj-10967	86	3	also	also	ADV
cusj-10967	86	4	allows	allow	VERB
cusj-10967	86	5	immune	immune	ADJ
cusj-10967	86	6	cells	cell	NOUN
cusj-10967	86	7	to	to	PART
cusj-10967	86	8	infiltrate	infiltrate	VERB
cusj-10967	86	9	tumors	tumor	NOUN
cusj-10967	86	10	and	and	CCONJ
cusj-10967	86	11	destroy	destroy	VERB
cusj-10967	86	12	cancer	cancer	NOUN
cusj-10967	86	13	cells	cell	NOUN
cusj-10967	86	14	.	.	PUNCT
cusj-10967	87	1	this	this	DET
cusj-10967	87	2	approach	approach	NOUN
cusj-10967	87	3	is	be	AUX
cusj-10967	87	4	generally	generally	ADV
cusj-10967	87	5	safe	safe	ADJ
cusj-10967	87	6	since	since	SCONJ
cusj-10967	87	7	the	the	DET
cusj-10967	87	8	direct	direct	ADJ
cusj-10967	87	9	cause	cause	NOUN
cusj-10967	87	10	of	of	ADP
cusj-10967	87	11	cancer	cancer	NOUN
cusj-10967	87	12	cell	cell	NOUN
cusj-10967	87	13	death	death	NOUN
cusj-10967	87	14	is	be	AUX
cusj-10967	87	15	the	the	DET
cusj-10967	87	16	immune	immune	ADJ
cusj-10967	87	17	response	response	NOUN
cusj-10967	87	18	.	.	PUNCT
cusj-10967	88	1	additionally	additionally	ADV
cusj-10967	88	2	,	,	PUNCT
cusj-10967	88	3	there	there	PRON
cusj-10967	88	4	are	be	VERB
cusj-10967	88	5	a	a	DET
cusj-10967	88	6	few	few	ADJ
cusj-10967	88	7	signaling	signal	VERB
cusj-10967	88	8	pathways	pathway	NOUN
cusj-10967	88	9	that	that	PRON
cusj-10967	88	10	are	be	AUX
cusj-10967	88	11	upregulated	upregulate	VERB
cusj-10967	88	12	in	in	ADP
cusj-10967	88	13	cancer	cancer	NOUN
cusj-10967	88	14	cells	cell	NOUN
cusj-10967	88	15	but	but	CCONJ
cusj-10967	88	16	not	not	PART
cusj-10967	88	17	in	in	ADP
cusj-10967	88	18	healthy	healthy	ADJ
cusj-10967	88	19	cells	cell	NOUN
cusj-10967	88	20	.	.	PUNCT
cusj-10967	89	1	upregulating	upregulating	NOUN
cusj-10967	89	2	or	or	CCONJ
cusj-10967	89	3	downregulating	downregulating	NOUN
cusj-10967	89	4	these	these	DET
cusj-10967	89	5	pathways	pathway	NOUN
cusj-10967	89	6	appropriately	appropriately	ADV
cusj-10967	89	7	could	could	AUX
cusj-10967	89	8	disrupt	disrupt	VERB
cusj-10967	89	9	the	the	DET
cusj-10967	89	10	tumor	tumor	NOUN
cusj-10967	89	11	microenvironment	microenvironment	NOUN
cusj-10967	89	12	and	and	CCONJ
cusj-10967	89	13	reduce	reduce	VERB
cusj-10967	89	14	immune	immune	ADJ
cusj-10967	89	15	exclusion	exclusion	NOUN
cusj-10967	89	16	.	.	PUNCT
cusj-10967	90	1	enhancing	enhance	VERB
cusj-10967	90	2	virus	virus	NOUN
cusj-10967	90	3	efficiency	efficiency	NOUN
cusj-10967	90	4	engineered	engineer	VERB
cusj-10967	90	5	ovs	ovs	NOUN
cusj-10967	90	6	are	be	AUX
cusj-10967	90	7	designed	design	VERB
cusj-10967	90	8	using	use	VERB
cusj-10967	90	9	one	one	NUM
cusj-10967	90	10	or	or	CCONJ
cusj-10967	90	11	more	more	ADV
cusj-10967	90	12	genetic	genetic	ADJ
cusj-10967	90	13	and	and	CCONJ
cusj-10967	90	14	structural	structural	ADJ
cusj-10967	90	15	modifications	modification	NOUN
cusj-10967	90	16	to	to	PART
cusj-10967	90	17	cause	cause	VERB
cusj-10967	90	18	an	an	DET
cusj-10967	90	19	antitumor	antitumor	PROPN
cusj-10967	90	20	effect	effect	NOUN
cusj-10967	90	21	.	.	PUNCT
cusj-10967	91	1	ovs	ovs	NOUN
cusj-10967	92	1	with	with	ADP
cusj-10967	92	2	one	one	NUM
cusj-10967	92	3	or	or	CCONJ
cusj-10967	92	4	more	more	ADJ
cusj-10967	92	5	such	such	ADJ
cusj-10967	92	6	improvements	improvement	NOUN
cusj-10967	92	7	can	can	AUX
cusj-10967	92	8	be	be	AUX
cusj-10967	92	9	further	far	ADV
cusj-10967	92	10	improved	improve	VERB
cusj-10967	92	11	by	by	ADP
cusj-10967	92	12	making	make	VERB
cusj-10967	92	13	additional	additional	ADJ
cusj-10967	92	14	modifications	modification	NOUN
cusj-10967	92	15	that	that	PRON
cusj-10967	92	16	enhance	enhance	VERB
cusj-10967	92	17	efficacy	efficacy	NOUN
cusj-10967	92	18	without	without	ADP
cusj-10967	92	19	compromising	compromise	VERB
cusj-10967	92	20	safety	safety	NOUN
cusj-10967	92	21	.	.	PUNCT
cusj-10967	93	1	these	these	DET
cusj-10967	93	2	modifications	modification	NOUN
cusj-10967	93	3	can	can	AUX
cusj-10967	93	4	take	take	VERB
cusj-10967	93	5	the	the	DET
cusj-10967	93	6	form	form	NOUN
cusj-10967	93	7	of	of	ADP
cusj-10967	93	8	increased	increase	VERB
cusj-10967	93	9	levels	level	NOUN
cusj-10967	93	10	of	of	ADP
cusj-10967	93	11	surface	surface	NOUN
cusj-10967	93	12	proteins	protein	NOUN
cusj-10967	93	13	or	or	CCONJ
cusj-10967	93	14	signaling	signal	VERB
cusj-10967	93	15	molecules	molecule	NOUN
cusj-10967	93	16	,	,	PUNCT
cusj-10967	93	17	as	as	ADV
cusj-10967	93	18	well	well	ADV
cusj-10967	93	19	as	as	ADP
cusj-10967	93	20	directly	directly	ADV
cusj-10967	93	21	causing	cause	VERB
cusj-10967	93	22	the	the	DET
cusj-10967	93	23	death	death	NOUN
cusj-10967	93	24	of	of	ADP
cusj-10967	93	25	cancer	cancer	NOUN
cusj-10967	93	26	cells.12	cells.12	NOUN
cusj-10967	93	27	enhancing	enhance	VERB
cusj-10967	93	28	modifications	modification	NOUN
cusj-10967	93	29	could	could	AUX
cusj-10967	93	30	also	also	ADV
cusj-10967	93	31	address	address	VERB
cusj-10967	93	32	different	different	ADJ
cusj-10967	93	33	barriers	barrier	NOUN
cusj-10967	93	34	to	to	ADP
cusj-10967	93	35	antitumor	antitumor	PROPN
cusj-10967	93	36	effectiveness	effectiveness	NOUN
cusj-10967	93	37	,	,	PUNCT
cusj-10967	93	38	such	such	ADJ
cusj-10967	93	39	as	as	ADP
cusj-10967	93	40	signaling	signal	VERB
cusj-10967	93	41	from	from	ADP
cusj-10967	93	42	tumor	tumor	NOUN
cusj-10967	93	43	cells	cell	NOUN
cusj-10967	93	44	or	or	CCONJ
cusj-10967	93	45	the	the	DET
cusj-10967	93	46	immune	immune	ADJ
cusj-10967	93	47	system	system	NOUN
cusj-10967	93	48	containing	contain	VERB
cusj-10967	93	49	and	and	CCONJ
cusj-10967	93	50	destroying	destroy	VERB
cusj-10967	93	51	ov	ov	ADP
cusj-10967	93	52	particles	particle	NOUN
cusj-10967	93	53	before	before	SCONJ
cusj-10967	93	54	they	they	PRON
cusj-10967	93	55	can	can	AUX
cusj-10967	93	56	take	take	VERB
cusj-10967	93	57	effect	effect	NOUN
cusj-10967	93	58	and	and	CCONJ
cusj-10967	93	59	destroy	destroy	VERB
cusj-10967	93	60	cancer	cancer	NOUN
cusj-10967	93	61	cells	cell	NOUN
cusj-10967	93	62	.	.	PUNCT
cusj-10967	94	1	some	some	DET
cusj-10967	94	2	cancer	cancer	NOUN
cusj-10967	94	3	types	type	NOUN
cusj-10967	94	4	,	,	PUNCT
cusj-10967	94	5	such	such	ADJ
cusj-10967	94	6	as	as	ADP
cusj-10967	94	7	acute	acute	ADJ
cusj-10967	94	8	myeloid	myeloid	NOUN
cusj-10967	94	9	leukemia	leukemia	NOUN
cusj-10967	94	10	,	,	PUNCT
cusj-10967	94	11	show	show	VERB
cusj-10967	94	12	limited	limited	ADJ
cusj-10967	94	13	susceptibility	susceptibility	NOUN
cusj-10967	94	14	to	to	ADP
cusj-10967	94	15	ovs	ovs	NOUN
cusj-10967	94	16	and	and	CCONJ
cusj-10967	94	17	require	require	VERB
cusj-10967	94	18	more	more	ADV
cusj-10967	94	19	effective	effective	ADJ
cusj-10967	94	20	viral	viral	ADJ
cusj-10967	94	21	vectors	vector	NOUN
cusj-10967	94	22	and	and	CCONJ
cusj-10967	94	23	active	active	ADJ
cusj-10967	94	24	agents	agent	NOUN
cusj-10967	94	25	.	.	PUNCT
cusj-10967	95	1	one	one	NUM
cusj-10967	95	2	molecule	molecule	NOUN
cusj-10967	95	3	utilized	utilize	VERB
cusj-10967	95	4	by	by	ADP
cusj-10967	95	5	engineered	engineer	VERB
cusj-10967	95	6	ovs	ovs	NOUN
cusj-10967	95	7	to	to	PART
cusj-10967	95	8	cause	cause	VERB
cusj-10967	95	9	an	an	DET
cusj-10967	95	10	antitumor	antitumor	PROPN
cusj-10967	95	11	effect	effect	NOUN
cusj-10967	95	12	is	be	AUX
cusj-10967	95	13	tumor	tumor	NOUN
cusj-10967	95	14	necrosis	necrosis	NOUN
cusj-10967	95	15	factor	factor	NOUN
cusj-10967	95	16	-	-	PUNCT
cusj-10967	95	17	related	relate	VERB
cusj-10967	95	18	apoptosis	apoptosis	NOUN
cusj-10967	95	19	-	-	PUNCT
cusj-10967	95	20	inducing	induce	VERB
cusj-10967	95	21	ligand	ligand	NOUN
cusj-10967	95	22	(	(	PUNCT
cusj-10967	95	23	trail	trail	NOUN
cusj-10967	95	24	)	)	PUNCT
cusj-10967	95	25	.	.	PUNCT
cusj-10967	96	1	this	this	DET
cusj-10967	96	2	immune	immune	ADJ
cusj-10967	96	3	factor	factor	NOUN
cusj-10967	96	4	can	can	AUX
cusj-10967	96	5	be	be	AUX
cusj-10967	96	6	expressed	express	VERB
cusj-10967	96	7	on	on	ADP
cusj-10967	96	8	the	the	DET
cusj-10967	96	9	surface	surface	NOUN
cusj-10967	96	10	of	of	ADP
cusj-10967	96	11	ovs	ovs	NOUN
cusj-10967	96	12	and	and	CCONJ
cusj-10967	96	13	binds	bind	VERB
cusj-10967	96	14	to	to	PART
cusj-10967	96	15	trail	trail	NOUN
cusj-10967	96	16	receptors	receptor	NOUN
cusj-10967	96	17	on	on	ADP
cusj-10967	96	18	the	the	DET
cusj-10967	96	19	surface	surface	NOUN
cusj-10967	96	20	of	of	ADP
cusj-10967	96	21	cancer	cancer	NOUN
cusj-10967	96	22	cells	cell	NOUN
cusj-10967	96	23	to	to	PART
cusj-10967	96	24	initiate	initiate	VERB
cusj-10967	96	25	a	a	DET
cusj-10967	96	26	signaling	signal	VERB
cusj-10967	96	27	pathway	pathway	NOUN
cusj-10967	96	28	that	that	PRON
cusj-10967	96	29	causes	cause	VERB
cusj-10967	96	30	cell	cell	NOUN
cusj-10967	96	31	death	death	NOUN
cusj-10967	96	32	.	.	PUNCT
cusj-10967	97	1	wang	wang	PROPN
cusj-10967	97	2	and	and	CCONJ
cusj-10967	97	3	colleagues	colleague	NOUN
cusj-10967	97	4	aimed	aim	VERB
cusj-10967	97	5	to	to	PART
cusj-10967	97	6	enhance	enhance	VERB
cusj-10967	97	7	an	an	DET
cusj-10967	97	8	engineered	engineer	VERB
cusj-10967	97	9	ov	ov	NOUN
cusj-10967	97	10	with	with	ADP
cusj-10967	97	11	additional	additional	ADJ
cusj-10967	97	12	trail	trail	NOUN
cusj-10967	97	13	to	to	PART
cusj-10967	97	14	cause	cause	VERB
cusj-10967	97	15	a	a	DET
cusj-10967	97	16	greater	great	ADJ
cusj-10967	97	17	antitumor	antitumor	NOUN
cusj-10967	97	18	effect.13	effect.13	NOUN
cusj-10967	97	19	the	the	DET
cusj-10967	97	20	researchers	researcher	NOUN
cusj-10967	97	21	had	have	AUX
cusj-10967	97	22	previously	previously	ADV
cusj-10967	97	23	engineered	engineer	VERB
cusj-10967	97	24	an	an	DET
cusj-10967	97	25	ov	ov	NOUN
cusj-10967	97	26	to	to	PART
cusj-10967	97	27	express	express	VERB
cusj-10967	97	28	trail	trail	NOUN
cusj-10967	97	29	on	on	ADP
cusj-10967	97	30	its	its	PRON
cusj-10967	97	31	protein	protein	NOUN
cusj-10967	97	32	shell	shell	NOUN
cusj-10967	97	33	that	that	PRON
cusj-10967	97	34	showed	show	VERB
cusj-10967	97	35	antitumor	antitumor	PROPN
cusj-10967	97	36	activity	activity	NOUN
cusj-10967	97	37	.	.	PUNCT
cusj-10967	98	1	they	they	PRON
cusj-10967	98	2	recognized	recognize	VERB
cusj-10967	98	3	that	that	SCONJ
cusj-10967	98	4	additional	additional	ADJ
cusj-10967	98	5	trail	trail	NOUN
cusj-10967	98	6	could	could	AUX
cusj-10967	98	7	be	be	AUX
cusj-10967	98	8	bound	bind	VERB
cusj-10967	98	9	to	to	ADP
cusj-10967	98	10	their	their	PRON
cusj-10967	98	11	ov	ov	NOUN
cusj-10967	98	12	through	through	ADP
cusj-10967	98	13	a	a	DET
cusj-10967	98	14	structural	structural	ADJ
cusj-10967	98	15	attachment	attachment	NOUN
cusj-10967	98	16	and	and	CCONJ
cusj-10967	98	17	experimentally	experimentally	ADV
cusj-10967	98	18	achieved	achieve	VERB
cusj-10967	98	19	this	this	PRON
cusj-10967	98	20	through	through	ADP
cusj-10967	98	21	a	a	DET
cusj-10967	98	22	zipper	zipper	NOUN
cusj-10967	98	23	domain	domain	NOUN
cusj-10967	98	24	.	.	PUNCT
cusj-10967	99	1	this	this	DET
cusj-10967	99	2	addition	addition	NOUN
cusj-10967	99	3	of	of	ADP
cusj-10967	99	4	trail	trail	NOUN
cusj-10967	99	5	improved	improve	VERB
cusj-10967	99	6	the	the	DET
cusj-10967	99	7	antitumor	antitumor	PROPN
cusj-10967	99	8	effectiveness	effectiveness	NOUN
cusj-10967	99	9	of	of	ADP
cusj-10967	99	10	the	the	DET
cusj-10967	99	11	ov	ov	PROPN
cusj-10967	99	12	against	against	ADP
cusj-10967	99	13	acute	acute	ADJ
cusj-10967	99	14	myeloid	myeloid	NOUN
cusj-10967	99	15	leukemia	leukemia	NOUN
cusj-10967	99	16	when	when	SCONJ
cusj-10967	99	17	compared	compare	VERB
cusj-10967	99	18	to	to	ADP
cusj-10967	99	19	the	the	DET
cusj-10967	99	20	first	first	ADJ
cusj-10967	99	21	iteration	iteration	NOUN
cusj-10967	99	22	of	of	ADP
cusj-10967	99	23	their	their	PRON
cusj-10967	99	24	trail	trail	NOUN
cusj-10967	99	25	-	-	PUNCT
cusj-10967	99	26	enhanced	enhance	VERB
cusj-10967	99	27	ov	ov	NOUN
cusj-10967	99	28	.	.	PUNCT
cusj-10967	100	1	certain	certain	ADJ
cusj-10967	100	2	types	type	NOUN
cusj-10967	100	3	of	of	ADP
cusj-10967	100	4	cancer	cancer	NOUN
cusj-10967	100	5	,	,	PUNCT
cusj-10967	100	6	including	include	VERB
cusj-10967	100	7	acute	acute	ADJ
cusj-10967	100	8	myeloid	myeloid	ADJ
cusj-10967	100	9	leukemia	leukemia	NOUN
cusj-10967	100	10	,	,	PUNCT
cusj-10967	100	11	may	may	AUX
cusj-10967	100	12	be	be	AUX
cusj-10967	100	13	resistant	resistant	ADJ
cusj-10967	100	14	to	to	ADP
cusj-10967	100	15	the	the	DET
cusj-10967	100	16	effects	effect	NOUN
cusj-10967	100	17	of	of	ADP
cusj-10967	100	18	trail	trail	NOUN
cusj-10967	100	19	signaling	signaling	NOUN
cusj-10967	100	20	.	.	PUNCT
cusj-10967	101	1	the	the	DET
cusj-10967	101	2	mechanism	mechanism	NOUN
cusj-10967	101	3	behind	behind	ADP
cusj-10967	101	4	this	this	DET
cusj-10967	101	5	resistance	resistance	NOUN
cusj-10967	101	6	is	be	AUX
cusj-10967	101	7	a	a	DET
cusj-10967	101	8	reduction	reduction	NOUN
cusj-10967	101	9	of	of	ADP
cusj-10967	101	10	trail	trail	NOUN
cusj-10967	101	11	receptors	receptor	NOUN
cusj-10967	101	12	in	in	ADP
cusj-10967	101	13	the	the	DET
cusj-10967	101	14	cancer	cancer	NOUN
cusj-10967	101	15	cells	cell	NOUN
cusj-10967	101	16	,	,	PUNCT
cusj-10967	101	17	leading	lead	VERB
cusj-10967	101	18	to	to	ADP
cusj-10967	101	19	fewer	few	ADJ
cusj-10967	101	20	opportunities	opportunity	NOUN
cusj-10967	101	21	for	for	ADP
cusj-10967	101	22	trail	trail	NOUN
cusj-10967	101	23	on	on	ADP
cusj-10967	101	24	the	the	DET
cusj-10967	101	25	ov	ov	PROPN
cusj-10967	101	26	to	to	PART
cusj-10967	101	27	bind	bind	VERB
cusj-10967	101	28	and	and	CCONJ
cusj-10967	101	29	initiate	initiate	VERB
cusj-10967	101	30	the	the	DET
cusj-10967	101	31	signaling	signal	VERB
cusj-10967	101	32	pathway	pathway	NOUN
cusj-10967	101	33	.	.	PUNCT
cusj-10967	102	1	due	due	ADP
cusj-10967	102	2	to	to	ADP
cusj-10967	102	3	the	the	DET
cusj-10967	102	4	nature	nature	NOUN
cusj-10967	102	5	of	of	ADP
cusj-10967	102	6	this	this	DET
cusj-10967	102	7	resistance	resistance	NOUN
cusj-10967	102	8	columbia	columbia	PROPN
cusj-10967	102	9	undergraduate	undergraduate	PROPN
cusj-10967	102	10	science	science	PROPN
cusj-10967	102	11	journal	journal	PROPN
cusj-10967	102	12	vol	vol	NOUN
cusj-10967	102	13	.	.	PROPN
cusj-10967	102	14	18	18	NUM
cusj-10967	102	15	,	,	PUNCT
cusj-10967	102	16	2024	2024	NUM
cusj-10967	102	17	manjila	manjila	PROPN
cusj-10967	102	18	mechanism	mechanism	NOUN
cusj-10967	102	19	,	,	PUNCT
cusj-10967	102	20	increasing	increase	VERB
cusj-10967	102	21	the	the	DET
cusj-10967	102	22	availability	availability	NOUN
cusj-10967	102	23	of	of	ADP
cusj-10967	102	24	trail	trail	NOUN
cusj-10967	102	25	is	be	AUX
cusj-10967	102	26	not	not	PART
cusj-10967	102	27	sufficient	sufficient	ADJ
cusj-10967	102	28	to	to	PART
cusj-10967	102	29	induce	induce	VERB
cusj-10967	102	30	cell	cell	NOUN
cusj-10967	102	31	death	death	NOUN
cusj-10967	102	32	in	in	ADP
cusj-10967	102	33	cancer	cancer	NOUN
cusj-10967	102	34	cells	cell	NOUN
cusj-10967	102	35	.	.	PUNCT
cusj-10967	103	1	ginsenosides	ginsenoside	NOUN
cusj-10967	103	2	,	,	PUNCT
cusj-10967	103	3	compounds	compound	NOUN
cusj-10967	103	4	derived	derive	VERB
cusj-10967	103	5	from	from	ADP
cusj-10967	103	6	ginseng	ginseng	NOUN
cusj-10967	103	7	,	,	PUNCT
cusj-10967	103	8	were	be	AUX
cusj-10967	103	9	previously	previously	ADV
cusj-10967	103	10	shown	show	VERB
cusj-10967	103	11	to	to	PART
cusj-10967	103	12	increase	increase	VERB
cusj-10967	103	13	the	the	DET
cusj-10967	103	14	availability	availability	NOUN
cusj-10967	103	15	of	of	ADP
cusj-10967	103	16	trail	trail	NOUN
cusj-10967	103	17	receptors	receptor	NOUN
cusj-10967	103	18	in	in	ADP
cusj-10967	103	19	cancer	cancer	NOUN
cusj-10967	103	20	cells.13	cells.13	PROPN
cusj-10967	103	21	wang	wang	PROPN
cusj-10967	103	22	and	and	CCONJ
cusj-10967	103	23	colleagues	colleague	NOUN
cusj-10967	103	24	investigated	investigate	VERB
cusj-10967	103	25	the	the	DET
cusj-10967	103	26	role	role	NOUN
cusj-10967	103	27	of	of	ADP
cusj-10967	103	28	the	the	DET
cusj-10967	103	29	ginsenoside	ginsenoside	PROPN
cusj-10967	103	30	rh	rh	PROPN
cusj-10967	103	31	(	(	PUNCT
cusj-10967	103	32	steroid	steroid	NOUN
cusj-10967	103	33	glycosides	glycoside	NOUN
cusj-10967	103	34	)	)	PUNCT
cusj-10967	103	35	in	in	ADP
cusj-10967	103	36	amplifying	amplify	VERB
cusj-10967	103	37	the	the	DET
cusj-10967	103	38	antitumor	antitumor	PROPN
cusj-10967	103	39	effect	effect	NOUN
cusj-10967	103	40	of	of	ADP
cusj-10967	103	41	their	their	PRON
cusj-10967	103	42	trail	trail	NOUN
cusj-10967	103	43	-	-	PUNCT
cusj-10967	103	44	enhanced	enhance	VERB
cusj-10967	103	45	ov	ov	NOUN
cusj-10967	103	46	.	.	PUNCT
cusj-10967	104	1	they	they	PRON
cusj-10967	104	2	found	find	VERB
cusj-10967	104	3	that	that	SCONJ
cusj-10967	104	4	rh	rh	NOUN
cusj-10967	104	5	activity	activity	NOUN
cusj-10967	104	6	led	lead	VERB
cusj-10967	104	7	to	to	ADP
cusj-10967	104	8	greater	great	ADJ
cusj-10967	104	9	expression	expression	NOUN
cusj-10967	104	10	of	of	ADP
cusj-10967	104	11	trail	trail	NOUN
cusj-10967	104	12	receptors	receptor	NOUN
cusj-10967	104	13	on	on	ADP
cusj-10967	104	14	the	the	DET
cusj-10967	104	15	surface	surface	NOUN
cusj-10967	104	16	of	of	ADP
cusj-10967	104	17	cancer	cancer	NOUN
cusj-10967	104	18	cells	cell	NOUN
cusj-10967	104	19	.	.	PUNCT
cusj-10967	105	1	in	in	ADP
cusj-10967	105	2	conjunction	conjunction	NOUN
cusj-10967	105	3	,	,	PUNCT
cusj-10967	105	4	the	the	DET
cusj-10967	105	5	inclusion	inclusion	NOUN
cusj-10967	105	6	of	of	ADP
cusj-10967	105	7	rh	rh	PROPN
cusj-10967	105	8	in	in	ADP
cusj-10967	105	9	the	the	DET
cusj-10967	105	10	treatment	treatment	NOUN
cusj-10967	105	11	course	course	NOUN
cusj-10967	105	12	increased	increase	VERB
cusj-10967	105	13	cancer	cancer	NOUN
cusj-10967	105	14	cell	cell	NOUN
cusj-10967	105	15	death	death	NOUN
cusj-10967	105	16	as	as	SCONJ
cusj-10967	105	17	trail	trail	NOUN
cusj-10967	105	18	had	have	VERB
cusj-10967	105	19	more	more	ADJ
cusj-10967	105	20	receptors	receptor	NOUN
cusj-10967	105	21	to	to	PART
cusj-10967	105	22	bind	bind	VERB
cusj-10967	105	23	to	to	ADP
cusj-10967	105	24	.	.	PUNCT
cusj-10967	106	1	this	this	PRON
cusj-10967	106	2	demonstrates	demonstrate	VERB
cusj-10967	106	3	that	that	SCONJ
cusj-10967	106	4	ov	ov	PROPN
cusj-10967	106	5	enhancement	enhancement	NOUN
cusj-10967	106	6	can	can	AUX
cusj-10967	106	7	be	be	AUX
cusj-10967	106	8	further	far	ADV
cusj-10967	106	9	improved	improve	VERB
cusj-10967	106	10	using	use	VERB
cusj-10967	106	11	synergistic	synergistic	ADJ
cusj-10967	106	12	treatment	treatment	NOUN
cusj-10967	106	13	with	with	ADP
cusj-10967	106	14	other	other	ADJ
cusj-10967	106	15	compounds	compound	NOUN
cusj-10967	106	16	,	,	PUNCT
cusj-10967	106	17	including	include	VERB
cusj-10967	106	18	natural	natural	ADJ
cusj-10967	106	19	compounds	compound	NOUN
cusj-10967	106	20	as	as	ADP
cusj-10967	106	21	in	in	ADP
cusj-10967	106	22	the	the	DET
cusj-10967	106	23	case	case	NOUN
cusj-10967	106	24	of	of	ADP
cusj-10967	106	25	ginsenosides	ginsenoside	NOUN
cusj-10967	106	26	.	.	PUNCT
cusj-10967	107	1	other	other	ADJ
cusj-10967	107	2	research	research	NOUN
cusj-10967	107	3	groups	group	NOUN
cusj-10967	107	4	have	have	AUX
cusj-10967	107	5	taken	take	VERB
cusj-10967	107	6	the	the	DET
cusj-10967	107	7	approach	approach	NOUN
cusj-10967	107	8	of	of	ADP
cusj-10967	107	9	enhancing	enhance	VERB
cusj-10967	107	10	viral	viral	ADJ
cusj-10967	107	11	efficiency	efficiency	NOUN
cusj-10967	107	12	by	by	ADP
cusj-10967	107	13	focusing	focus	VERB
cusj-10967	107	14	efforts	effort	NOUN
cusj-10967	107	15	on	on	ADP
cusj-10967	107	16	different	different	ADJ
cusj-10967	107	17	structural	structural	ADJ
cusj-10967	107	18	and	and	CCONJ
cusj-10967	107	19	genetic	genetic	ADJ
cusj-10967	107	20	targets	target	NOUN
cusj-10967	107	21	.	.	PUNCT
cusj-10967	108	1	menotti	menotti	NOUN
cusj-10967	108	2	and	and	CCONJ
cusj-10967	108	3	colleagues	colleague	NOUN
cusj-10967	108	4	modified	modify	VERB
cusj-10967	108	5	an	an	DET
cusj-10967	108	6	engineered	engineer	VERB
cusj-10967	108	7	herpes	herpe	NOUN
cusj-10967	108	8	simplex	simplex	NOUN
cusj-10967	108	9	virus	virus	NOUN
cusj-10967	108	10	to	to	PART
cusj-10967	108	11	target	target	VERB
cusj-10967	108	12	cancer	cancer	NOUN
cusj-10967	108	13	cell	cell	NOUN
cusj-10967	108	14	-	-	PUNCT
cusj-10967	108	15	specific	specific	ADJ
cusj-10967	108	16	receptors	receptor	NOUN
cusj-10967	108	17	by	by	ADP
cusj-10967	108	18	inserting	insert	VERB
cusj-10967	108	19	different	different	ADJ
cusj-10967	108	20	single	single	ADJ
cusj-10967	108	21	chain	chain	NOUN
cusj-10967	108	22	antibodies	antibodie	VERB
cusj-10967	108	23	into	into	ADP
cusj-10967	108	24	the	the	DET
cusj-10967	108	25	viral	viral	ADJ
cusj-10967	108	26	protein	protein	NOUN
cusj-10967	108	27	structure.14	structure.14	NOUN
cusj-10967	108	28	this	this	DET
cusj-10967	108	29	modification	modification	NOUN
cusj-10967	108	30	increased	increase	VERB
cusj-10967	108	31	the	the	DET
cusj-10967	108	32	number	number	NOUN
cusj-10967	108	33	of	of	ADP
cusj-10967	108	34	cancer	cancer	NOUN
cusj-10967	108	35	cells	cell	NOUN
cusj-10967	108	36	that	that	PRON
cusj-10967	108	37	can	can	AUX
cusj-10967	108	38	be	be	AUX
cusj-10967	108	39	targeted	target	VERB
cusj-10967	108	40	by	by	ADP
cusj-10967	108	41	the	the	DET
cusj-10967	108	42	ov	ov	PROPN
cusj-10967	108	43	since	since	SCONJ
cusj-10967	108	44	different	different	ADJ
cusj-10967	108	45	antibodies	antibody	NOUN
cusj-10967	108	46	could	could	AUX
cusj-10967	108	47	be	be	AUX
cusj-10967	108	48	inserted	insert	VERB
cusj-10967	108	49	,	,	PUNCT
cusj-10967	108	50	making	make	VERB
cusj-10967	108	51	that	that	DET
cusj-10967	108	52	virus	virus	NOUN
cusj-10967	108	53	more	more	ADV
cusj-10967	108	54	useful	useful	ADJ
cusj-10967	108	55	across	across	ADP
cusj-10967	108	56	more	more	ADJ
cusj-10967	108	57	cancer	cancer	NOUN
cusj-10967	108	58	types	type	NOUN
cusj-10967	108	59	.	.	PUNCT
cusj-10967	109	1	kim	kim	PROPN
cusj-10967	109	2	and	and	CCONJ
cusj-10967	109	3	colleagues	colleague	NOUN
cusj-10967	109	4	increased	increase	VERB
cusj-10967	109	5	viral	viral	ADJ
cusj-10967	109	6	expression	expression	NOUN
cusj-10967	109	7	of	of	ADP
cusj-10967	109	8	interleukin-12	interleukin-12	NOUN
cusj-10967	109	9	and	and	CCONJ
cusj-10967	109	10	granulocyte	granulocyte	ADJ
cusj-10967	109	11	-	-	PUNCT
cusj-10967	109	12	macrophage	macrophage	ADJ
cusj-10967	109	13	colony	colony	NOUN
cusj-10967	109	14	-	-	PUNCT
cusj-10967	109	15	stimulating	stimulate	VERB
cusj-10967	109	16	factor	factor	NOUN
cusj-10967	109	17	to	to	PART
cusj-10967	109	18	amplify	amplify	VERB
cusj-10967	109	19	immune	immune	ADJ
cusj-10967	109	20	response.15	response.15	PROPN
cusj-10967	109	21	more	more	ADJ
cusj-10967	109	22	cancer	cancer	NOUN
cusj-10967	109	23	cells	cell	NOUN
cusj-10967	109	24	will	will	AUX
cusj-10967	109	25	be	be	AUX
cusj-10967	109	26	destroyed	destroy	VERB
cusj-10967	109	27	if	if	SCONJ
cusj-10967	109	28	more	more	ADJ
cusj-10967	109	29	immune	immune	ADJ
cusj-10967	109	30	cells	cell	NOUN
cusj-10967	109	31	are	be	AUX
cusj-10967	109	32	activated	activate	VERB
cusj-10967	109	33	and	and	CCONJ
cusj-10967	109	34	localize	localize	VERB
cusj-10967	109	35	to	to	ADP
cusj-10967	109	36	the	the	DET
cusj-10967	109	37	tumor	tumor	NOUN
cusj-10967	109	38	site	site	NOUN
cusj-10967	109	39	.	.	PUNCT
cusj-10967	110	1	rivadeneira	rivadeneira	PROPN
cusj-10967	110	2	and	and	CCONJ
cusj-10967	110	3	colleagues	colleague	NOUN
cusj-10967	110	4	engineered	engineer	VERB
cusj-10967	110	5	an	an	DET
cusj-10967	110	6	oncolytic	oncolytic	ADJ
cusj-10967	110	7	vaccinia	vaccinia	NOUN
cusj-10967	110	8	virus	virus	NOUN
cusj-10967	110	9	to	to	PART
cusj-10967	110	10	express	express	VERB
cusj-10967	110	11	the	the	DET
cusj-10967	110	12	adipokine	adipokine	ADJ
cusj-10967	110	13	leptin	leptin	NOUN
cusj-10967	110	14	in	in	ADP
cusj-10967	110	15	infected	infected	ADJ
cusj-10967	110	16	tumor	tumor	NOUN
cusj-10967	110	17	cells.16	cells.16	NOUN
cusj-10967	110	18	furthermore	furthermore	ADV
cusj-10967	110	19	,	,	PUNCT
cusj-10967	110	20	leptin	leptin	NOUN
cusj-10967	110	21	activates	activate	VERB
cusj-10967	110	22	a	a	DET
cusj-10967	110	23	signaling	signal	VERB
cusj-10967	110	24	pathway	pathway	NOUN
cusj-10967	110	25	that	that	PRON
cusj-10967	110	26	contributes	contribute	VERB
cusj-10967	110	27	to	to	ADP
cusj-10967	110	28	an	an	DET
cusj-10967	110	29	increased	increase	VERB
cusj-10967	110	30	t	t	NOUN
cusj-10967	110	31	cell	cell	NOUN
cusj-10967	110	32	response	response	NOUN
cusj-10967	110	33	and	and	CCONJ
cusj-10967	110	34	prolonged	prolonged	ADJ
cusj-10967	110	35	immune	immune	ADJ
cusj-10967	110	36	memory	memory	NOUN
cusj-10967	110	37	.	.	PUNCT
cusj-10967	111	1	these	these	DET
cusj-10967	111	2	studies	study	NOUN
cusj-10967	111	3	demonstrate	demonstrate	VERB
cusj-10967	111	4	the	the	DET
cusj-10967	111	5	variety	variety	NOUN
cusj-10967	111	6	of	of	ADP
cusj-10967	111	7	methods	method	NOUN
cusj-10967	111	8	that	that	PRON
cusj-10967	111	9	are	be	AUX
cusj-10967	111	10	available	available	ADJ
cusj-10967	111	11	for	for	ADP
cusj-10967	111	12	enhancing	enhance	VERB
cusj-10967	111	13	ovs	ovs	NOUN
cusj-10967	111	14	.	.	PUNCT
cusj-10967	112	1	a	a	DET
cusj-10967	112	2	major	major	ADJ
cusj-10967	112	3	barrier	barrier	NOUN
cusj-10967	112	4	to	to	ADP
cusj-10967	112	5	achieving	achieve	VERB
cusj-10967	112	6	greater	great	ADJ
cusj-10967	112	7	viral	viral	ADJ
cusj-10967	112	8	efficiency	efficiency	NOUN
cusj-10967	112	9	is	be	AUX
cusj-10967	112	10	the	the	DET
cusj-10967	112	11	containment	containment	NOUN
cusj-10967	112	12	and	and	CCONJ
cusj-10967	112	13	destruction	destruction	NOUN
cusj-10967	112	14	of	of	ADP
cusj-10967	112	15	ovs	ovs	NOUN
cusj-10967	112	16	by	by	ADP
cusj-10967	112	17	the	the	DET
cusj-10967	112	18	human	human	ADJ
cusj-10967	112	19	immune	immune	ADJ
cusj-10967	112	20	system	system	NOUN
cusj-10967	112	21	.	.	PUNCT
cusj-10967	113	1	if	if	SCONJ
cusj-10967	113	2	the	the	DET
cusj-10967	113	3	immune	immune	ADJ
cusj-10967	113	4	response	response	NOUN
cusj-10967	113	5	is	be	AUX
cusj-10967	113	6	activated	activate	VERB
cusj-10967	113	7	by	by	ADP
cusj-10967	113	8	the	the	DET
cusj-10967	113	9	presence	presence	NOUN
cusj-10967	113	10	of	of	ADP
cusj-10967	113	11	viral	viral	ADJ
cusj-10967	113	12	particles	particle	NOUN
cusj-10967	113	13	in	in	ADP
cusj-10967	113	14	the	the	DET
cusj-10967	113	15	body	body	NOUN
cusj-10967	113	16	,	,	PUNCT
cusj-10967	113	17	the	the	DET
cusj-10967	113	18	ov	ov	PROPN
cusj-10967	113	19	will	will	AUX
cusj-10967	113	20	not	not	PART
cusj-10967	113	21	have	have	VERB
cusj-10967	113	22	any	any	DET
cusj-10967	113	23	significant	significant	ADJ
cusj-10967	113	24	antitumor	antitumor	PROPN
cusj-10967	113	25	effect	effect	NOUN
cusj-10967	113	26	since	since	SCONJ
cusj-10967	113	27	the	the	DET
cusj-10967	113	28	virus	virus	NOUN
cusj-10967	113	29	will	will	AUX
cusj-10967	113	30	not	not	PART
cusj-10967	113	31	reach	reach	VERB
cusj-10967	113	32	the	the	DET
cusj-10967	113	33	tumor	tumor	NOUN
cusj-10967	113	34	in	in	ADP
cusj-10967	113	35	sufficient	sufficient	ADJ
cusj-10967	113	36	quantity	quantity	NOUN
cusj-10967	113	37	.	.	PUNCT
cusj-10967	114	1	atasheva	atasheva	PROPN
cusj-10967	114	2	and	and	CCONJ
cusj-10967	114	3	colleagues	colleague	NOUN
cusj-10967	114	4	addressed	address	VERB
cusj-10967	114	5	this	this	DET
cusj-10967	114	6	issue	issue	NOUN
cusj-10967	114	7	through	through	ADP
cusj-10967	114	8	the	the	DET
cusj-10967	114	9	development	development	NOUN
cusj-10967	114	10	of	of	ADP
cusj-10967	114	11	an	an	DET
cusj-10967	114	12	oncolytic	oncolytic	ADJ
cusj-10967	114	13	adenovirus	adenovirus	NOUN
cusj-10967	114	14	that	that	PRON
cusj-10967	114	15	avoids	avoid	VERB
cusj-10967	114	16	immune	immune	ADJ
cusj-10967	114	17	response	response	NOUN
cusj-10967	114	18	and	and	CCONJ
cusj-10967	114	19	containment	containment	NOUN
cusj-10967	114	20	by	by	ADP
cusj-10967	114	21	mutating	mutate	VERB
cusj-10967	114	22	the	the	DET
cusj-10967	114	23	region	region	NOUN
cusj-10967	114	24	of	of	ADP
cusj-10967	114	25	the	the	DET
cusj-10967	114	26	viral	viral	ADJ
cusj-10967	114	27	protein	protein	NOUN
cusj-10967	114	28	that	that	PRON
cusj-10967	114	29	host	host	NOUN
cusj-10967	114	30	antibodies	antibodie	VERB
cusj-10967	114	31	bind	bind	VERB
cusj-10967	114	32	to.17	to.17	NOUN
cusj-10967	114	33	the	the	DET
cusj-10967	114	34	resulting	result	VERB
cusj-10967	114	35	ov	ov	PROPN
cusj-10967	114	36	was	be	AUX
cusj-10967	114	37	able	able	ADJ
cusj-10967	114	38	to	to	PART
cusj-10967	114	39	cause	cause	VERB
cusj-10967	114	40	a	a	DET
cusj-10967	114	41	systemic	systemic	ADJ
cusj-10967	114	42	antitumor	antitumor	PROPN
cusj-10967	114	43	effect	effect	NOUN
cusj-10967	114	44	without	without	ADP
cusj-10967	114	45	being	be	AUX
cusj-10967	114	46	hindered	hinder	VERB
cusj-10967	114	47	by	by	ADP
cusj-10967	114	48	the	the	DET
cusj-10967	114	49	immune	immune	ADJ
cusj-10967	114	50	response	response	NOUN
cusj-10967	114	51	since	since	SCONJ
cusj-10967	114	52	antibodies	antibody	NOUN
cusj-10967	114	53	could	could	AUX
cusj-10967	114	54	no	no	ADV
cusj-10967	114	55	longer	long	ADV
cusj-10967	114	56	bind	bind	VERB
cusj-10967	114	57	to	to	ADP
cusj-10967	114	58	the	the	DET
cusj-10967	114	59	virus	virus	NOUN
cusj-10967	114	60	.	.	PUNCT
cusj-10967	115	1	this	this	DET
cusj-10967	115	2	study	study	NOUN
cusj-10967	115	3	highlights	highlight	VERB
cusj-10967	115	4	the	the	DET
cusj-10967	115	5	need	need	NOUN
cusj-10967	115	6	for	for	ADP
cusj-10967	115	7	ovs	ovs	NOUN
cusj-10967	115	8	engineered	engineer	VERB
cusj-10967	115	9	to	to	PART
cusj-10967	115	10	avoid	avoid	VERB
cusj-10967	115	11	triggering	trigger	VERB
cusj-10967	115	12	an	an	DET
cusj-10967	115	13	immune	immune	ADJ
cusj-10967	115	14	response	response	NOUN
cusj-10967	115	15	from	from	ADP
cusj-10967	115	16	the	the	DET
cusj-10967	115	17	host	host	NOUN
cusj-10967	115	18	organism	organism	NOUN
cusj-10967	115	19	,	,	PUNCT
cusj-10967	115	20	particularly	particularly	ADV
cusj-10967	115	21	as	as	SCONJ
cusj-10967	115	22	ovs	ovs	NOUN
cusj-10967	115	23	become	become	VERB
cusj-10967	115	24	increasingly	increasingly	ADV
cusj-10967	115	25	effective	effective	ADJ
cusj-10967	115	26	at	at	ADP
cusj-10967	115	27	destroying	destroy	VERB
cusj-10967	115	28	tumors	tumor	NOUN
cusj-10967	115	29	.	.	PUNCT
cusj-10967	116	1	in	in	ADP
cusj-10967	116	2	a	a	DET
cusj-10967	116	3	similar	similar	ADJ
cusj-10967	116	4	manner	manner	NOUN
cusj-10967	116	5	,	,	PUNCT
cusj-10967	116	6	bah	bah	NOUN
cusj-10967	116	7	and	and	CCONJ
cusj-10967	116	8	colleagues	colleague	NOUN
cusj-10967	116	9	engineered	engineer	VERB
cusj-10967	116	10	an	an	DET
cusj-10967	116	11	oncolytic	oncolytic	ADJ
cusj-10967	116	12	measles	measle	NOUN
cusj-10967	116	13	virus	virus	NOUN
cusj-10967	116	14	to	to	PART
cusj-10967	116	15	better	well	ADV
cusj-10967	116	16	avoid	avoid	VERB
cusj-10967	116	17	targeting	target	VERB
cusj-10967	116	18	by	by	ADP
cusj-10967	116	19	the	the	DET
cusj-10967	116	20	immune	immune	ADJ
cusj-10967	116	21	system	system	NOUN
cusj-10967	116	22	by	by	ADP
cusj-10967	116	23	replacing	replace	VERB
cusj-10967	116	24	key	key	ADJ
cusj-10967	116	25	surface	surface	NOUN
cusj-10967	116	26	glycoproteins	glycoprotein	NOUN
cusj-10967	116	27	with	with	ADP
cusj-10967	116	28	those	those	PRON
cusj-10967	116	29	from	from	ADP
cusj-10967	116	30	another	another	DET
cusj-10967	116	31	virus.18	virus.18	NOUN
cusj-10967	116	32	this	this	PRON
cusj-10967	116	33	is	be	AUX
cusj-10967	116	34	another	another	DET
cusj-10967	116	35	method	method	NOUN
cusj-10967	116	36	by	by	ADP
cusj-10967	116	37	which	which	PRON
cusj-10967	116	38	ovs	ovs	NOUN
cusj-10967	116	39	can	can	AUX
cusj-10967	116	40	be	be	AUX
cusj-10967	116	41	engineered	engineer	VERB
cusj-10967	116	42	to	to	PART
cusj-10967	116	43	demonstrate	demonstrate	VERB
cusj-10967	116	44	stealth	stealth	NOUN
cusj-10967	116	45	against	against	ADP
cusj-10967	116	46	the	the	DET
cusj-10967	116	47	immune	immune	ADJ
cusj-10967	116	48	system	system	NOUN
cusj-10967	116	49	.	.	PUNCT
cusj-10967	117	1	while	while	SCONJ
cusj-10967	117	2	further	further	ADJ
cusj-10967	117	3	laboratory	laboratory	NOUN
cusj-10967	117	4	studies	study	NOUN
cusj-10967	117	5	are	be	AUX
cusj-10967	117	6	being	be	AUX
cusj-10967	117	7	performed	perform	VERB
cusj-10967	117	8	,	,	PUNCT
cusj-10967	117	9	a	a	DET
cusj-10967	117	10	few	few	ADJ
cusj-10967	117	11	ovs	ovs	NOUN
cusj-10967	117	12	have	have	AUX
cusj-10967	117	13	also	also	ADV
cusj-10967	117	14	moved	move	VERB
cusj-10967	117	15	into	into	ADP
cusj-10967	117	16	the	the	DET
cusj-10967	117	17	clinical	clinical	ADJ
cusj-10967	117	18	phase	phase	NOUN
cusj-10967	117	19	.	.	PUNCT
cusj-10967	118	1	zhang	zhang	PROPN
cusj-10967	118	2	and	and	CCONJ
cusj-10967	118	3	colleagues	colleague	NOUN
cusj-10967	118	4	performed	perform	VERB
cusj-10967	118	5	phase	phase	NOUN
cusj-10967	118	6	i	i	PRON
cusj-10967	118	7	and	and	CCONJ
cusj-10967	118	8	ii	ii	PROPN
cusj-10967	118	9	clinical	clinical	ADJ
cusj-10967	118	10	trials	trial	NOUN
cusj-10967	118	11	on	on	ADP
cusj-10967	118	12	the	the	DET
cusj-10967	118	13	antitumor	antitumor	PROPN
cusj-10967	118	14	effectiveness	effectiveness	NOUN
cusj-10967	118	15	of	of	ADP
cusj-10967	118	16	an	an	DET
cusj-10967	118	17	oncolytic	oncolytic	ADJ
cusj-10967	118	18	herpes	herpe	NOUN
cusj-10967	118	19	simplex	simplex	NOUN
cusj-10967	118	20	virus	virus	NOUN
cusj-10967	118	21	designed	design	VERB
cusj-10967	118	22	to	to	PART
cusj-10967	118	23	express	express	VERB
cusj-10967	118	24	granulocyte	granulocyte	ADJ
cusj-10967	118	25	-	-	PUNCT
cusj-10967	118	26	macrophage	macrophage	ADJ
cusj-10967	118	27	colony	colony	NOUN
cusj-10967	118	28	-	-	PUNCT
cusj-10967	118	29	stimulating	stimulate	VERB
cusj-10967	118	30	factor	factor	NOUN
cusj-10967	118	31	,	,	PUNCT
cusj-10967	118	32	which	which	PRON
cusj-10967	118	33	enhances	enhance	VERB
cusj-10967	118	34	immune	immune	ADJ
cusj-10967	118	35	response.19	response.19	NOUN
cusj-10967	118	36	the	the	DET
cusj-10967	118	37	researchers	researcher	NOUN
cusj-10967	118	38	found	find	VERB
cusj-10967	118	39	that	that	SCONJ
cusj-10967	118	40	the	the	DET
cusj-10967	118	41	ov	ov	PROPN
cusj-10967	118	42	treatment	treatment	NOUN
cusj-10967	118	43	was	be	AUX
cusj-10967	118	44	effective	effective	ADJ
cusj-10967	118	45	in	in	ADP
cusj-10967	118	46	metastatic	metastatic	ADJ
cusj-10967	118	47	,	,	PUNCT
cusj-10967	118	48	treatment	treatment	NOUN
cusj-10967	118	49	-	-	PUNCT
cusj-10967	118	50	resistant	resistant	ADJ
cusj-10967	118	51	esophageal	esophageal	ADJ
cusj-10967	118	52	and	and	CCONJ
cusj-10967	118	53	rectal	rectal	ADJ
cusj-10967	118	54	cancer	cancer	NOUN
cusj-10967	118	55	.	.	PUNCT
cusj-10967	119	1	the	the	DET
cusj-10967	119	2	addition	addition	NOUN
cusj-10967	119	3	of	of	ADP
cusj-10967	119	4	an	an	DET
cusj-10967	119	5	antibody	antibody	NOUN
cusj-10967	119	6	for	for	ADP
cusj-10967	119	7	a	a	DET
cusj-10967	119	8	tumor	tumor	NOUN
cusj-10967	119	9	cell	cell	NOUN
cusj-10967	119	10	receptor	receptor	NOUN
cusj-10967	119	11	that	that	PRON
cusj-10967	119	12	suppresses	suppress	VERB
cusj-10967	119	13	immune	immune	ADJ
cusj-10967	119	14	activity	activity	NOUN
cusj-10967	119	15	enhanced	enhance	VERB
cusj-10967	119	16	the	the	DET
cusj-10967	119	17	oncolytic	oncolytic	ADJ
cusj-10967	119	18	effectiveness	effectiveness	NOUN
cusj-10967	119	19	of	of	ADP
cusj-10967	119	20	the	the	DET
cusj-10967	119	21	virus	virus	NOUN
cusj-10967	119	22	.	.	PUNCT
cusj-10967	120	1	side	side	ADJ
cusj-10967	120	2	effects	effect	NOUN
cusj-10967	120	3	observed	observe	VERB
cusj-10967	120	4	in	in	ADP
cusj-10967	120	5	the	the	DET
cusj-10967	120	6	patients	patient	NOUN
cusj-10967	120	7	were	be	AUX
cusj-10967	120	8	relatively	relatively	ADV
cusj-10967	120	9	mild	mild	ADJ
cusj-10967	120	10	,	,	PUNCT
cusj-10967	120	11	and	and	CCONJ
cusj-10967	120	12	improved	improve	VERB
cusj-10967	120	13	immune	immune	ADJ
cusj-10967	120	14	infiltration	infiltration	NOUN
cusj-10967	120	15	of	of	ADP
cusj-10967	120	16	the	the	DET
cusj-10967	120	17	tumor	tumor	NOUN
cusj-10967	120	18	was	be	AUX
cusj-10967	120	19	demonstrated	demonstrate	VERB
cusj-10967	120	20	.	.	PUNCT
cusj-10967	121	1	these	these	DET
cusj-10967	121	2	results	result	NOUN
cusj-10967	121	3	are	be	AUX
cusj-10967	121	4	significant	significant	ADJ
cusj-10967	121	5	because	because	SCONJ
cusj-10967	121	6	they	they	PRON
cusj-10967	121	7	show	show	VERB
cusj-10967	121	8	that	that	DET
cusj-10967	121	9	ovs	ovs	NOUN
cusj-10967	121	10	that	that	PRON
cusj-10967	121	11	are	be	AUX
cusj-10967	121	12	not	not	PART
cusj-10967	121	13	effective	effective	ADJ
cusj-10967	121	14	against	against	ADP
cusj-10967	121	15	certain	certain	ADJ
cusj-10967	121	16	types	type	NOUN
cusj-10967	121	17	of	of	ADP
cusj-10967	121	18	cancer	cancer	NOUN
cusj-10967	121	19	may	may	AUX
cusj-10967	121	20	be	be	AUX
cusj-10967	121	21	enhanced	enhance	VERB
cusj-10967	121	22	to	to	PART
cusj-10967	121	23	become	become	VERB
cusj-10967	121	24	effective	effective	ADJ
cusj-10967	121	25	.	.	PUNCT
cusj-10967	122	1	fares	fare	NOUN
cusj-10967	122	2	and	and	CCONJ
cusj-10967	122	3	colleagues	colleague	NOUN
cusj-10967	122	4	found	find	VERB
cusj-10967	122	5	that	that	SCONJ
cusj-10967	122	6	an	an	DET
cusj-10967	122	7	oncolytic	oncolytic	ADJ
cusj-10967	122	8	adenovirus	adenovirus	NOUN
cusj-10967	122	9	showed	show	VERB
cusj-10967	122	10	antitumor	antitumor	PROPN
cusj-10967	122	11	effect	effect	NOUN
cusj-10967	122	12	in	in	ADP
cusj-10967	122	13	a	a	DET
cusj-10967	122	14	phase	phase	NOUN
cusj-10967	122	15	i	i	PRON
cusj-10967	122	16	clinical	clinical	ADJ
cusj-10967	122	17	trial	trial	NOUN
cusj-10967	122	18	of	of	ADP
cusj-10967	122	19	glioblastoma	glioblastoma	NOUN
cusj-10967	122	20	patients.20	patients.20	NOUN
cusj-10967	122	21	glioblastoma	glioblastoma	NOUN
cusj-10967	122	22	is	be	AUX
cusj-10967	122	23	a	a	DET
cusj-10967	122	24	very	very	ADV
cusj-10967	122	25	aggressive	aggressive	ADJ
cusj-10967	122	26	cancer	cancer	NOUN
cusj-10967	122	27	type	type	NOUN
cusj-10967	122	28	,	,	PUNCT
cusj-10967	122	29	and	and	CCONJ
cusj-10967	122	30	results	result	NOUN
cusj-10967	122	31	indicating	indicate	VERB
cusj-10967	122	32	antitumor	antitumor	NOUN
cusj-10967	122	33	activity	activity	NOUN
cusj-10967	122	34	could	could	AUX
cusj-10967	122	35	be	be	AUX
cusj-10967	122	36	indicative	indicative	ADJ
cusj-10967	122	37	of	of	ADP
cusj-10967	122	38	the	the	DET
cusj-10967	122	39	potential	potential	NOUN
cusj-10967	122	40	for	for	ADP
cusj-10967	122	41	clinical	clinical	PROPN
cusj-10967	122	42	columbia	columbia	PROPN
cusj-10967	122	43	undergraduate	undergraduate	PROPN
cusj-10967	122	44	science	science	PROPN
cusj-10967	122	45	journal	journal	PROPN
cusj-10967	122	46	vol	vol	NOUN
cusj-10967	122	47	.	.	PROPN
cusj-10967	122	48	18	18	NUM
cusj-10967	122	49	,	,	PUNCT
cusj-10967	122	50	2024	2024	NUM
cusj-10967	122	51	manjila	manjila	PROPN
cusj-10967	122	52	application	application	NOUN
cusj-10967	122	53	after	after	SCONJ
cusj-10967	122	54	additional	additional	ADJ
cusj-10967	122	55	research	research	NOUN
cusj-10967	122	56	is	be	AUX
cusj-10967	122	57	performed	perform	VERB
cusj-10967	122	58	.	.	PUNCT
cusj-10967	123	1	enhancing	enhance	VERB
cusj-10967	123	2	preexisting	preexist	VERB
cusj-10967	123	3	ovs	ovs	NOUN
cusj-10967	123	4	provides	provide	VERB
cusj-10967	123	5	more	more	ADV
cusj-10967	123	6	effective	effective	ADJ
cusj-10967	123	7	therapeutics	therapeutic	NOUN
cusj-10967	123	8	.	.	PUNCT
cusj-10967	124	1	due	due	ADP
cusj-10967	124	2	to	to	ADP
cusj-10967	124	3	the	the	DET
cusj-10967	124	4	recent	recent	ADJ
cusj-10967	124	5	interest	interest	NOUN
cusj-10967	124	6	in	in	ADP
cusj-10967	124	7	oncolytic	oncolytic	ADJ
cusj-10967	124	8	virotherapy	virotherapy	NOUN
cusj-10967	124	9	,	,	PUNCT
cusj-10967	124	10	many	many	ADJ
cusj-10967	124	11	different	different	ADJ
cusj-10967	124	12	ovs	ovs	NOUN
cusj-10967	124	13	have	have	AUX
cusj-10967	124	14	been	be	AUX
cusj-10967	124	15	engineered	engineer	VERB
cusj-10967	124	16	with	with	ADP
cusj-10967	124	17	a	a	DET
cusj-10967	124	18	few	few	ADJ
cusj-10967	124	19	entering	enter	VERB
cusj-10967	124	20	clinical	clinical	ADJ
cusj-10967	124	21	trials.12	trials.12	NOUN
cusj-10967	124	22	these	these	DET
cusj-10967	124	23	ovs	ovs	NOUN
cusj-10967	124	24	that	that	PRON
cusj-10967	124	25	have	have	AUX
cusj-10967	124	26	already	already	ADV
cusj-10967	124	27	shown	show	VERB
cusj-10967	124	28	antitumor	antitumor	PROPN
cusj-10967	124	29	effectiveness	effectiveness	NOUN
cusj-10967	124	30	could	could	AUX
cusj-10967	124	31	be	be	AUX
cusj-10967	124	32	made	make	VERB
cusj-10967	124	33	more	more	ADV
cusj-10967	124	34	effective	effective	ADJ
cusj-10967	124	35	through	through	ADP
cusj-10967	124	36	different	different	ADJ
cusj-10967	124	37	engineering	engineering	NOUN
cusj-10967	124	38	approaches	approach	NOUN
cusj-10967	124	39	and	and	CCONJ
cusj-10967	124	40	antitumor	antitumor	PROPN
cusj-10967	124	41	mechanisms	mechanism	NOUN
cusj-10967	124	42	.	.	PUNCT
cusj-10967	125	1	therefore	therefore	ADV
cusj-10967	125	2	,	,	PUNCT
cusj-10967	125	3	future	future	ADJ
cusj-10967	125	4	research	research	NOUN
cusj-10967	125	5	is	be	AUX
cusj-10967	125	6	not	not	PART
cusj-10967	125	7	limited	limit	VERB
cusj-10967	125	8	to	to	ADP
cusj-10967	125	9	the	the	DET
cusj-10967	125	10	development	development	NOUN
cusj-10967	125	11	of	of	ADP
cusj-10967	125	12	entirely	entirely	ADV
cusj-10967	125	13	novel	novel	ADJ
cusj-10967	125	14	ovs	ovs	NOUN
cusj-10967	125	15	.	.	PUNCT
cusj-10967	126	1	it	it	PRON
cusj-10967	126	2	may	may	AUX
cusj-10967	126	3	also	also	ADV
cusj-10967	126	4	potentially	potentially	ADV
cusj-10967	126	5	be	be	AUX
cusj-10967	126	6	more	more	ADV
cusj-10967	126	7	efficient	efficient	ADJ
cusj-10967	126	8	to	to	PART
cusj-10967	126	9	push	push	VERB
cusj-10967	126	10	enhanced	enhance	VERB
cusj-10967	126	11	ovs	ovs	NOUN
cusj-10967	126	12	into	into	ADP
cusj-10967	126	13	clinical	clinical	ADJ
cusj-10967	126	14	trials	trial	NOUN
cusj-10967	126	15	if	if	SCONJ
cusj-10967	126	16	the	the	DET
cusj-10967	126	17	parent	parent	NOUN
cusj-10967	126	18	strain	strain	NOUN
cusj-10967	126	19	was	be	AUX
cusj-10967	126	20	already	already	ADV
cusj-10967	126	21	in	in	ADP
cusj-10967	126	22	clinical	clinical	ADJ
cusj-10967	126	23	trials	trial	NOUN
cusj-10967	126	24	.	.	PUNCT
cusj-10967	127	1	treating	treat	VERB
cusj-10967	127	2	slow	slow	ADV
cusj-10967	127	3	-	-	PUNCT
cusj-10967	127	4	growing	grow	VERB
cusj-10967	127	5	tumors	tumor	NOUN
cusj-10967	127	6	different	different	ADJ
cusj-10967	127	7	cancer	cancer	NOUN
cusj-10967	127	8	types	type	NOUN
cusj-10967	127	9	have	have	VERB
cusj-10967	127	10	different	different	ADJ
cusj-10967	127	11	pathophysiology	pathophysiology	NOUN
cusj-10967	127	12	and	and	CCONJ
cusj-10967	127	13	rates	rate	NOUN
cusj-10967	127	14	of	of	ADP
cusj-10967	127	15	metastasis	metastasis	NOUN
cusj-10967	127	16	.	.	PUNCT
cusj-10967	128	1	tumors	tumor	NOUN
cusj-10967	128	2	grow	grow	VERB
cusj-10967	128	3	at	at	ADP
cusj-10967	128	4	different	different	ADJ
cusj-10967	128	5	rates	rate	NOUN
cusj-10967	128	6	depending	depend	VERB
cusj-10967	128	7	on	on	ADP
cusj-10967	128	8	the	the	DET
cusj-10967	128	9	type	type	NOUN
cusj-10967	128	10	of	of	ADP
cusj-10967	128	11	cancer	cancer	NOUN
cusj-10967	128	12	,	,	PUNCT
cusj-10967	128	13	anti	anti	ADJ
cusj-10967	128	14	-	-	ADJ
cusj-10967	128	15	cancer	cancer	ADJ
cusj-10967	128	16	immune	immune	ADJ
cusj-10967	128	17	response	response	NOUN
cusj-10967	128	18	,	,	PUNCT
cusj-10967	128	19	and	and	CCONJ
cusj-10967	128	20	other	other	ADJ
cusj-10967	128	21	host	host	NOUN
cusj-10967	128	22	-	-	PUNCT
cusj-10967	128	23	related	relate	VERB
cusj-10967	128	24	factors	factor	NOUN
cusj-10967	128	25	.	.	PUNCT
cusj-10967	129	1	the	the	DET
cusj-10967	129	2	growth	growth	NOUN
cusj-10967	129	3	of	of	ADP
cusj-10967	129	4	tumors	tumor	NOUN
cusj-10967	129	5	are	be	AUX
cusj-10967	129	6	directly	directly	ADV
cusj-10967	129	7	the	the	DET
cusj-10967	129	8	result	result	NOUN
cusj-10967	129	9	of	of	ADP
cusj-10967	129	10	cancer	cancer	NOUN
cusj-10967	129	11	cell	cell	NOUN
cusj-10967	129	12	proliferation	proliferation	NOUN
cusj-10967	129	13	and	and	CCONJ
cusj-10967	129	14	accumulation	accumulation	NOUN
cusj-10967	129	15	.	.	PUNCT
cusj-10967	130	1	engineered	engineer	VERB
cusj-10967	130	2	ovs	ovs	NOUN
cusj-10967	130	3	are	be	AUX
cusj-10967	130	4	able	able	ADJ
cusj-10967	130	5	to	to	PART
cusj-10967	130	6	target	target	VERB
cusj-10967	130	7	tumors	tumor	NOUN
cusj-10967	130	8	that	that	PRON
cusj-10967	130	9	grow	grow	VERB
cusj-10967	130	10	quickly	quickly	ADV
cusj-10967	130	11	by	by	ADP
cusj-10967	130	12	spreading	spread	VERB
cusj-10967	130	13	through	through	ADP
cusj-10967	130	14	tumors	tumor	NOUN
cusj-10967	130	15	via	via	ADP
cusj-10967	130	16	daughter	daughter	NOUN
cusj-10967	130	17	cells	cell	NOUN
cusj-10967	130	18	produced	produce	VERB
cusj-10967	130	19	by	by	ADP
cusj-10967	130	20	cancer	cancer	NOUN
cusj-10967	130	21	cell	cell	NOUN
cusj-10967	130	22	division.21	division.21	VERB
cusj-10967	130	23	slower	slow	ADV
cusj-10967	130	24	-	-	PUNCT
cusj-10967	130	25	growing	grow	VERB
cusj-10967	130	26	tumors	tumor	NOUN
cusj-10967	130	27	undergo	undergo	VERB
cusj-10967	130	28	cell	cell	NOUN
cusj-10967	130	29	division	division	NOUN
cusj-10967	130	30	at	at	ADP
cusj-10967	130	31	a	a	DET
cusj-10967	130	32	slower	slow	ADJ
cusj-10967	130	33	rate	rate	NOUN
cusj-10967	130	34	,	,	PUNCT
cusj-10967	130	35	and	and	CCONJ
cusj-10967	130	36	therefore	therefore	ADV
cusj-10967	130	37	ovs	ovs	NOUN
cusj-10967	130	38	that	that	PRON
cusj-10967	130	39	primarily	primarily	ADV
cusj-10967	130	40	proliferate	proliferate	VERB
cusj-10967	130	41	in	in	ADP
cusj-10967	130	42	a	a	DET
cusj-10967	130	43	tumor	tumor	NOUN
cusj-10967	130	44	through	through	ADP
cusj-10967	130	45	cell	cell	NOUN
cusj-10967	130	46	division	division	NOUN
cusj-10967	130	47	are	be	AUX
cusj-10967	130	48	not	not	PART
cusj-10967	130	49	as	as	ADV
cusj-10967	130	50	effective	effective	ADJ
cusj-10967	130	51	at	at	ADP
cusj-10967	130	52	combating	combat	VERB
cusj-10967	130	53	the	the	DET
cusj-10967	130	54	cancer	cancer	NOUN
cusj-10967	130	55	cells	cell	NOUN
cusj-10967	130	56	.	.	PUNCT
cusj-10967	131	1	additionally	additionally	ADV
cusj-10967	131	2	,	,	PUNCT
cusj-10967	131	3	given	give	VERB
cusj-10967	131	4	that	that	SCONJ
cusj-10967	131	5	slow	slow	ADV
cusj-10967	131	6	-	-	PUNCT
cusj-10967	131	7	growing	grow	VERB
cusj-10967	131	8	tumors	tumor	NOUN
cusj-10967	131	9	usually	usually	ADV
cusj-10967	131	10	take	take	VERB
cusj-10967	131	11	an	an	DET
cusj-10967	131	12	extended	extended	ADJ
cusj-10967	131	13	period	period	NOUN
cusj-10967	131	14	of	of	ADP
cusj-10967	131	15	time	time	NOUN
cusj-10967	131	16	before	before	ADP
cusj-10967	131	17	becoming	become	VERB
cusj-10967	131	18	significantly	significantly	ADV
cusj-10967	131	19	dangerous	dangerous	ADJ
cusj-10967	131	20	to	to	ADP
cusj-10967	131	21	patients	patient	NOUN
cusj-10967	131	22	,	,	PUNCT
cusj-10967	131	23	there	there	PRON
cusj-10967	131	24	is	be	VERB
cusj-10967	131	25	more	more	ADJ
cusj-10967	131	26	time	time	NOUN
cusj-10967	131	27	to	to	PART
cusj-10967	131	28	administer	administer	VERB
cusj-10967	131	29	treatments	treatment	NOUN
cusj-10967	131	30	,	,	PUNCT
cusj-10967	131	31	and	and	CCONJ
cusj-10967	131	32	treatments	treatment	NOUN
cusj-10967	131	33	that	that	PRON
cusj-10967	131	34	could	could	AUX
cusj-10967	131	35	be	be	AUX
cusj-10967	131	36	very	very	ADV
cusj-10967	131	37	effective	effective	ADJ
cusj-10967	131	38	in	in	ADP
cusj-10967	131	39	the	the	DET
cusj-10967	131	40	long	long	ADJ
cusj-10967	131	41	-	-	PUNCT
cusj-10967	131	42	term	term	NOUN
cusj-10967	131	43	may	may	AUX
cusj-10967	131	44	have	have	VERB
cusj-10967	131	45	more	more	ADJ
cusj-10967	131	46	utility	utility	NOUN
cusj-10967	131	47	than	than	ADP
cusj-10967	131	48	those	those	PRON
cusj-10967	131	49	of	of	ADP
cusj-10967	131	50	the	the	DET
cusj-10967	131	51	short	short	ADJ
cusj-10967	131	52	term	term	NOUN
cusj-10967	131	53	.	.	PUNCT
cusj-10967	132	1	slow	slow	ADV
cusj-10967	132	2	-	-	PUNCT
cusj-10967	132	3	growing	grow	VERB
cusj-10967	132	4	tumors	tumor	NOUN
cusj-10967	132	5	may	may	AUX
cusj-10967	132	6	also	also	ADV
cusj-10967	132	7	exhibit	exhibit	VERB
cusj-10967	132	8	treatment	treatment	NOUN
cusj-10967	132	9	resistance	resistance	NOUN
cusj-10967	132	10	,	,	PUNCT
cusj-10967	132	11	which	which	PRON
cusj-10967	132	12	necessitates	necessitate	VERB
cusj-10967	132	13	ov	ov	ADP
cusj-10967	132	14	engineering	engineering	NOUN
cusj-10967	132	15	that	that	PRON
cusj-10967	132	16	overcomes	overcome	VERB
cusj-10967	132	17	resistance	resistance	NOUN
cusj-10967	132	18	mechanisms	mechanism	NOUN
cusj-10967	132	19	.	.	PUNCT
cusj-10967	133	1	ovs	ovs	PROPN
cusj-10967	133	2	require	require	VERB
cusj-10967	133	3	additional	additional	ADJ
cusj-10967	133	4	engineering	engineering	NOUN
cusj-10967	133	5	and	and	CCONJ
cusj-10967	133	6	investigation	investigation	NOUN
cusj-10967	133	7	to	to	PART
cusj-10967	133	8	move	move	VERB
cusj-10967	133	9	towards	towards	ADP
cusj-10967	133	10	the	the	DET
cusj-10967	133	11	development	development	NOUN
cusj-10967	133	12	of	of	ADP
cusj-10967	133	13	novel	novel	ADJ
cusj-10967	133	14	ovs	ovs	NOUN
cusj-10967	133	15	that	that	PRON
cusj-10967	133	16	utilize	utilize	VERB
cusj-10967	133	17	mechanisms	mechanism	NOUN
cusj-10967	133	18	of	of	ADP
cusj-10967	133	19	action	action	NOUN
cusj-10967	133	20	that	that	PRON
cusj-10967	133	21	are	be	AUX
cusj-10967	133	22	effective	effective	ADJ
cusj-10967	133	23	against	against	ADP
cusj-10967	133	24	slow	slow	ADV
cusj-10967	133	25	-	-	PUNCT
cusj-10967	133	26	growing	grow	VERB
cusj-10967	133	27	cancers	cancer	NOUN
cusj-10967	133	28	.	.	PUNCT
cusj-10967	134	1	fukuhara	fukuhara	NOUN
cusj-10967	134	2	and	and	CCONJ
cusj-10967	134	3	colleagues	colleague	NOUN
cusj-10967	134	4	sought	seek	VERB
cusj-10967	134	5	to	to	PART
cusj-10967	134	6	develop	develop	VERB
cusj-10967	134	7	an	an	DET
cusj-10967	134	8	ov	ov	NOUN
cusj-10967	134	9	that	that	PRON
cusj-10967	134	10	could	could	AUX
cusj-10967	134	11	be	be	AUX
cusj-10967	134	12	an	an	DET
cusj-10967	134	13	effective	effective	ADJ
cusj-10967	134	14	anti	anti	ADJ
cusj-10967	134	15	-	-	ADJ
cusj-10967	134	16	cancer	cancer	ADJ
cusj-10967	134	17	agent	agent	NOUN
cusj-10967	134	18	in	in	ADP
cusj-10967	134	19	slow	slow	ADV
cusj-10967	134	20	-	-	PUNCT
cusj-10967	134	21	growing	grow	VERB
cusj-10967	134	22	tumors	tumor	NOUN
cusj-10967	134	23	.	.	PUNCT
cusj-10967	135	1	they	they	PRON
cusj-10967	135	2	engineered	engineer	VERB
cusj-10967	135	3	an	an	DET
cusj-10967	135	4	oncolytic	oncolytic	ADJ
cusj-10967	135	5	herpes	herpe	NOUN
cusj-10967	135	6	simplex	simplex	NOUN
cusj-10967	135	7	virus	virus	NOUN
cusj-10967	135	8	known	know	VERB
cusj-10967	135	9	as	as	ADP
cusj-10967	135	10	thtert	thtert	NOUN
cusj-10967	135	11	which	which	PRON
cusj-10967	135	12	retains	retain	VERB
cusj-10967	135	13	the	the	DET
cusj-10967	135	14	infection	infection	NOUN
cusj-10967	135	15	specificity	specificity	NOUN
cusj-10967	135	16	of	of	ADP
cusj-10967	135	17	its	its	PRON
cusj-10967	135	18	parent	parent	NOUN
cusj-10967	135	19	strain	strain	NOUN
cusj-10967	135	20	while	while	SCONJ
cusj-10967	135	21	preventing	prevent	VERB
cusj-10967	135	22	protein	protein	NOUN
cusj-10967	135	23	synthesis	synthesis	NOUN
cusj-10967	135	24	shutdown	shutdown	NOUN
cusj-10967	135	25	in	in	ADP
cusj-10967	135	26	infected	infected	ADJ
cusj-10967	135	27	cancer	cancer	NOUN
cusj-10967	135	28	cells	cell	NOUN
cusj-10967	135	29	,	,	PUNCT
cusj-10967	135	30	leading	lead	VERB
cusj-10967	135	31	to	to	ADP
cusj-10967	135	32	virus	virus	NOUN
cusj-10967	135	33	proliferation	proliferation	NOUN
cusj-10967	135	34	that	that	PRON
cusj-10967	135	35	does	do	AUX
cusj-10967	135	36	not	not	PART
cusj-10967	135	37	damage	damage	VERB
cusj-10967	135	38	healthy	healthy	ADJ
cusj-10967	135	39	cells	cell	NOUN
cusj-10967	135	40	.	.	PUNCT
cusj-10967	136	1	the	the	DET
cusj-10967	136	2	researchers	researcher	NOUN
cusj-10967	136	3	found	find	VERB
cusj-10967	136	4	that	that	SCONJ
cusj-10967	136	5	the	the	DET
cusj-10967	136	6	ov	ov	PROPN
cusj-10967	136	7	was	be	AUX
cusj-10967	136	8	effective	effective	ADJ
cusj-10967	136	9	against	against	ADP
cusj-10967	136	10	slow	slow	ADV
cusj-10967	136	11	-	-	PUNCT
cusj-10967	136	12	growing	grow	VERB
cusj-10967	136	13	tumors	tumor	NOUN
cusj-10967	136	14	by	by	ADP
cusj-10967	136	15	maintaining	maintain	VERB
cusj-10967	136	16	a	a	DET
cusj-10967	136	17	high	high	ADJ
cusj-10967	136	18	viral	viral	ADJ
cusj-10967	136	19	load	load	NOUN
cusj-10967	136	20	despite	despite	SCONJ
cusj-10967	136	21	lower	low	ADJ
cusj-10967	136	22	cell	cell	NOUN
cusj-10967	136	23	division	division	NOUN
cusj-10967	136	24	rates.22	rates.22	NOUN
cusj-10967	136	25	additionally	additionally	ADV
cusj-10967	136	26	,	,	PUNCT
cusj-10967	136	27	they	they	PRON
cusj-10967	136	28	demonstrated	demonstrate	VERB
cusj-10967	136	29	that	that	SCONJ
cusj-10967	136	30	the	the	DET
cusj-10967	136	31	virus	virus	NOUN
cusj-10967	136	32	was	be	AUX
cusj-10967	136	33	safe	safe	ADJ
cusj-10967	136	34	for	for	ADP
cusj-10967	136	35	application	application	NOUN
cusj-10967	136	36	in	in	ADP
cusj-10967	136	37	brain	brain	NOUN
cusj-10967	136	38	tissue	tissue	NOUN
cusj-10967	136	39	,	,	PUNCT
cusj-10967	136	40	which	which	PRON
cusj-10967	136	41	is	be	AUX
cusj-10967	136	42	quite	quite	ADV
cusj-10967	136	43	susceptible	susceptible	ADJ
cusj-10967	136	44	to	to	ADP
cusj-10967	136	45	impairment	impairment	NOUN
cusj-10967	136	46	due	due	ADP
cusj-10967	136	47	to	to	ADP
cusj-10967	136	48	tissue	tissue	NOUN
cusj-10967	136	49	damage	damage	NOUN
cusj-10967	136	50	.	.	PUNCT
cusj-10967	137	1	these	these	DET
cusj-10967	137	2	findings	finding	NOUN
cusj-10967	137	3	indicate	indicate	VERB
cusj-10967	137	4	that	that	DET
cusj-10967	137	5	ovs	ovs	NOUN
cusj-10967	137	6	utilizing	utilize	VERB
cusj-10967	137	7	similar	similar	ADJ
cusj-10967	137	8	mechanisms	mechanism	NOUN
cusj-10967	137	9	may	may	AUX
cusj-10967	137	10	be	be	AUX
cusj-10967	137	11	suitable	suitable	ADJ
cusj-10967	137	12	for	for	ADP
cusj-10967	137	13	clinical	clinical	ADJ
cusj-10967	137	14	use	use	NOUN
cusj-10967	137	15	in	in	ADP
cusj-10967	137	16	the	the	DET
cusj-10967	137	17	treatment	treatment	NOUN
cusj-10967	137	18	of	of	ADP
cusj-10967	137	19	slow	slow	ADV
cusj-10967	137	20	-	-	PUNCT
cusj-10967	137	21	growing	grow	VERB
cusj-10967	137	22	tumors	tumor	NOUN
cusj-10967	137	23	.	.	PUNCT
cusj-10967	138	1	ov	ov	PROPN
cusj-10967	138	2	effectiveness	effectiveness	NOUN
cusj-10967	138	3	is	be	AUX
cusj-10967	138	4	shown	show	VERB
cusj-10967	138	5	to	to	PART
cusj-10967	138	6	not	not	PART
cusj-10967	138	7	be	be	AUX
cusj-10967	138	8	limited	limit	VERB
cusj-10967	138	9	to	to	ADP
cusj-10967	138	10	fast	fast	ADV
cusj-10967	138	11	-	-	PUNCT
cusj-10967	138	12	growing	grow	VERB
cusj-10967	138	13	tumors	tumor	NOUN
cusj-10967	138	14	and	and	CCONJ
cusj-10967	138	15	can	can	AUX
cusj-10967	138	16	be	be	AUX
cusj-10967	138	17	effective	effective	ADJ
cusj-10967	138	18	against	against	ADP
cusj-10967	138	19	slowgrowing	slowgrowe	VERB
cusj-10967	138	20	tumors	tumor	NOUN
cusj-10967	138	21	given	give	VERB
cusj-10967	138	22	the	the	DET
cusj-10967	138	23	necessary	necessary	ADJ
cusj-10967	138	24	modifications	modification	NOUN
cusj-10967	138	25	.	.	PUNCT
cusj-10967	139	1	the	the	DET
cusj-10967	139	2	researchers	researcher	NOUN
cusj-10967	139	3	also	also	ADV
cusj-10967	139	4	showed	show	VERB
cusj-10967	139	5	that	that	SCONJ
cusj-10967	139	6	the	the	DET
cusj-10967	139	7	ov	ov	PROPN
cusj-10967	139	8	is	be	AUX
cusj-10967	139	9	safe	safe	ADJ
cusj-10967	139	10	for	for	ADP
cusj-10967	139	11	healthy	healthy	ADJ
cusj-10967	139	12	tissue	tissue	NOUN
cusj-10967	139	13	and	and	CCONJ
cusj-10967	139	14	may	may	AUX
cusj-10967	139	15	not	not	PART
cusj-10967	139	16	pose	pose	VERB
cusj-10967	139	17	a	a	DET
cusj-10967	139	18	significant	significant	ADJ
cusj-10967	139	19	risk	risk	NOUN
cusj-10967	139	20	to	to	ADP
cusj-10967	139	21	the	the	DET
cusj-10967	139	22	host	host	NOUN
cusj-10967	139	23	organism	organism	NOUN
cusj-10967	139	24	.	.	PUNCT
cusj-10967	140	1	other	other	ADJ
cusj-10967	140	2	researchers	researcher	NOUN
cusj-10967	140	3	have	have	AUX
cusj-10967	140	4	investigated	investigate	VERB
cusj-10967	140	5	the	the	DET
cusj-10967	140	6	possibility	possibility	NOUN
cusj-10967	140	7	of	of	ADP
cusj-10967	140	8	ovs	ovs	NOUN
cusj-10967	140	9	that	that	PRON
cusj-10967	140	10	function	function	VERB
cusj-10967	140	11	effectively	effectively	ADV
cusj-10967	140	12	in	in	ADP
cusj-10967	140	13	slow	slow	ADV
cusj-10967	140	14	-	-	PUNCT
cusj-10967	140	15	growing	grow	VERB
cusj-10967	140	16	tumors	tumor	NOUN
cusj-10967	140	17	or	or	CCONJ
cusj-10967	140	18	have	have	VERB
cusj-10967	140	19	the	the	DET
cusj-10967	140	20	potential	potential	NOUN
cusj-10967	140	21	to	to	PART
cusj-10967	140	22	be	be	AUX
cusj-10967	140	23	useful	useful	ADJ
cusj-10967	140	24	towards	towards	ADP
cusj-10967	140	25	the	the	DET
cusj-10967	140	26	development	development	NOUN
cusj-10967	140	27	of	of	ADP
cusj-10967	140	28	such	such	ADJ
cusj-10967	140	29	ovs	ovs	NOUN
cusj-10967	140	30	.	.	PUNCT
cusj-10967	141	1	cao	cao	PROPN
cusj-10967	141	2	and	and	CCONJ
cusj-10967	141	3	colleagues	colleague	NOUN
cusj-10967	141	4	engineered	engineer	VERB
cusj-10967	141	5	an	an	DET
cusj-10967	141	6	oncolytic	oncolytic	ADJ
cusj-10967	141	7	vaccinia	vaccinia	NOUN
cusj-10967	141	8	virus	virus	NOUN
cusj-10967	141	9	that	that	PRON
cusj-10967	141	10	draws	draw	VERB
cusj-10967	141	11	macrophages	macrophage	NOUN
cusj-10967	141	12	towards	towards	ADP
cusj-10967	141	13	infected	infect	VERB
cusj-10967	141	14	tumor	tumor	NOUN
cusj-10967	141	15	cells.23	cells.23	PROPN
cusj-10967	141	16	the	the	DET
cusj-10967	141	17	involvement	involvement	NOUN
cusj-10967	141	18	of	of	ADP
cusj-10967	141	19	another	another	DET
cusj-10967	141	20	immune	immune	ADJ
cusj-10967	141	21	cell	cell	NOUN
cusj-10967	141	22	type	type	NOUN
cusj-10967	141	23	increases	increase	VERB
cusj-10967	141	24	the	the	DET
cusj-10967	141	25	number	number	NOUN
cusj-10967	141	26	of	of	ADP
cusj-10967	141	27	possible	possible	ADJ
cusj-10967	141	28	ov	ov	PROPN
cusj-10967	141	29	mechanisms	mechanism	NOUN
cusj-10967	141	30	that	that	PRON
cusj-10967	141	31	could	could	AUX
cusj-10967	141	32	be	be	AUX
cusj-10967	141	33	utilized	utilize	VERB
cusj-10967	141	34	by	by	ADP
cusj-10967	141	35	researchers	researcher	NOUN
cusj-10967	141	36	.	.	PUNCT
cusj-10967	142	1	liu	liu	PROPN
cusj-10967	142	2	and	and	CCONJ
cusj-10967	142	3	colleagues	colleague	NOUN
cusj-10967	142	4	engineered	engineer	VERB
cusj-10967	142	5	an	an	DET
cusj-10967	142	6	oncolytic	oncolytic	ADJ
cusj-10967	142	7	herpes	herpe	NOUN
cusj-10967	142	8	simplex	simplex	NOUN
cusj-10967	142	9	virus	virus	NOUN
cusj-10967	142	10	to	to	PART
cusj-10967	142	11	express	express	VERB
cusj-10967	142	12	cytosine	cytosine	ADJ
cusj-10967	142	13	deaminase	deaminase	NOUN
cusj-10967	142	14	for	for	ADP
cusj-10967	142	15	the	the	DET
cusj-10967	142	16	treatment	treatment	NOUN
cusj-10967	142	17	of	of	ADP
cusj-10967	142	18	uveal	uveal	ADJ
cusj-10967	142	19	melanoma.24	melanoma.24	NOUN
cusj-10967	142	20	this	this	PRON
cusj-10967	142	21	ov	ov	PROPN
cusj-10967	142	22	was	be	AUX
cusj-10967	142	23	designed	design	VERB
cusj-10967	142	24	to	to	PART
cusj-10967	142	25	treat	treat	VERB
cusj-10967	142	26	a	a	DET
cusj-10967	142	27	rare	rare	ADJ
cusj-10967	142	28	and	and	CCONJ
cusj-10967	142	29	chemotherapy	chemotherapy	NOUN
cusj-10967	142	30	-	-	ADJ
cusj-10967	142	31	resistant	resistant	ADJ
cusj-10967	142	32	cancer	cancer	NOUN
cusj-10967	142	33	type	type	NOUN
cusj-10967	142	34	,	,	PUNCT
cusj-10967	142	35	demonstrating	demonstrate	VERB
cusj-10967	142	36	the	the	DET
cusj-10967	142	37	need	need	NOUN
cusj-10967	142	38	for	for	ADP
cusj-10967	142	39	ovs	ovs	NOUN
cusj-10967	142	40	for	for	ADP
cusj-10967	142	41	uncommon	uncommon	ADJ
cusj-10967	142	42	cancers	cancer	NOUN
cusj-10967	142	43	.	.	PUNCT
cusj-10967	143	1	khalique	khalique	NOUN
cusj-10967	143	2	and	and	CCONJ
cusj-10967	143	3	colleagues	colleague	NOUN
cusj-10967	143	4	created	create	VERB
cusj-10967	143	5	an	an	DET
cusj-10967	143	6	oncolytic	oncolytic	ADJ
cusj-10967	143	7	herpes	herpe	NOUN
cusj-10967	143	8	virus	virus	NOUN
cusj-10967	143	9	that	that	PRON
cusj-10967	143	10	targets	target	VERB
cusj-10967	143	11	immunosuppressive	immunosuppressive	ADJ
cusj-10967	143	12	tumors	tumor	NOUN
cusj-10967	143	13	while	while	SCONJ
cusj-10967	143	14	simultaneously	simultaneously	ADV
cusj-10967	143	15	drawing	draw	VERB
cusj-10967	143	16	an	an	DET
cusj-10967	143	17	immune	immune	ADJ
cusj-10967	143	18	response	response	NOUN
cusj-10967	143	19	to	to	ADP
cusj-10967	143	20	cancer	cancer	NOUN
cusj-10967	143	21	cells.25	cells.25	PROPN
cusj-10967	143	22	multi	multi	ADJ
cusj-10967	143	23	-	-	ADJ
cusj-10967	143	24	function	function	ADJ
cusj-10967	143	25	ovs	ovs	NOUN
cusj-10967	143	26	could	could	AUX
cusj-10967	143	27	be	be	AUX
cusj-10967	143	28	effective	effective	ADJ
cusj-10967	143	29	against	against	ADP
cusj-10967	143	30	slow	slow	ADV
cusj-10967	143	31	-	-	PUNCT
cusj-10967	143	32	growing	grow	VERB
cusj-10967	143	33	tumors	tumor	NOUN
cusj-10967	143	34	,	,	PUNCT
cusj-10967	143	35	particularly	particularly	ADV
cusj-10967	143	36	if	if	SCONJ
cusj-10967	143	37	the	the	DET
cusj-10967	143	38	tumors	tumor	NOUN
cusj-10967	143	39	grow	grow	VERB
cusj-10967	143	40	at	at	ADP
cusj-10967	143	41	higher	high	ADJ
cusj-10967	143	42	or	or	CCONJ
cusj-10967	143	43	lower	low	ADJ
cusj-10967	143	44	rates	rate	NOUN
cusj-10967	143	45	over	over	ADP
cusj-10967	143	46	a	a	DET
cusj-10967	143	47	period	period	NOUN
cusj-10967	143	48	of	of	ADP
cusj-10967	143	49	time	time	NOUN
cusj-10967	143	50	.	.	PUNCT
cusj-10967	144	1	leoni	leoni	PROPN
cusj-10967	144	2	and	and	CCONJ
cusj-10967	144	3	colleagues	colleague	NOUN
cusj-10967	144	4	developed	develop	VERB
cusj-10967	144	5	a	a	DET
cusj-10967	144	6	noncancer	noncancer	NOUN
cusj-10967	144	7	cell	cell	NOUN
cusj-10967	144	8	line	line	NOUN
cusj-10967	144	9	for	for	ADP
cusj-10967	144	10	the	the	DET
cusj-10967	144	11	development	development	NOUN
cusj-10967	144	12	of	of	ADP
cusj-10967	144	13	ovs.26	ovs.26	VERB
cusj-10967	144	14	this	this	DET
cusj-10967	144	15	cell	cell	NOUN
cusj-10967	144	16	line	line	NOUN
cusj-10967	144	17	could	could	AUX
cusj-10967	144	18	be	be	AUX
cusj-10967	144	19	a	a	DET
cusj-10967	144	20	useful	useful	ADJ
cusj-10967	144	21	tool	tool	NOUN
cusj-10967	144	22	in	in	ADP
cusj-10967	144	23	the	the	DET
cusj-10967	144	24	engineering	engineering	NOUN
cusj-10967	144	25	of	of	ADP
cusj-10967	144	26	more	more	ADJ
cusj-10967	144	27	ovs	ovs	NOUN
cusj-10967	144	28	,	,	PUNCT
cusj-10967	144	29	particularly	particularly	ADV
cusj-10967	144	30	ovs	ovs	NOUN
cusj-10967	144	31	designed	design	VERB
cusj-10967	144	32	for	for	ADP
cusj-10967	144	33	slow	slow	ADV
cusj-10967	144	34	-	-	PUNCT
cusj-10967	144	35	growing	grow	VERB
cusj-10967	144	36	cancers	cancer	NOUN
cusj-10967	144	37	.	.	PUNCT
cusj-10967	145	1	columbia	columbia	PROPN
cusj-10967	145	2	undergraduate	undergraduate	PROPN
cusj-10967	145	3	science	science	PROPN
cusj-10967	145	4	journal	journal	PROPN
cusj-10967	145	5	vol	vol	NOUN
cusj-10967	145	6	.	.	PROPN
cusj-10967	145	7	18	18	NUM
cusj-10967	145	8	,	,	PUNCT
cusj-10967	145	9	2024	2024	NUM
cusj-10967	145	10	manjila	manjila	NOUN
cusj-10967	145	11	some	some	DET
cusj-10967	145	12	research	research	NOUN
cusj-10967	145	13	groups	group	NOUN
cusj-10967	145	14	have	have	AUX
cusj-10967	145	15	worked	work	VERB
cusj-10967	145	16	towards	towards	ADP
cusj-10967	145	17	the	the	DET
cusj-10967	145	18	development	development	NOUN
cusj-10967	145	19	of	of	ADP
cusj-10967	145	20	anti	anti	ADJ
cusj-10967	145	21	-	-	ADJ
cusj-10967	145	22	cancer	cancer	ADJ
cusj-10967	145	23	vaccines	vaccine	NOUN
cusj-10967	145	24	which	which	PRON
cusj-10967	145	25	enhance	enhance	VERB
cusj-10967	145	26	long	long	ADJ
cusj-10967	145	27	-	-	PUNCT
cusj-10967	145	28	term	term	NOUN
cusj-10967	145	29	,	,	PUNCT
cusj-10967	145	30	antitumor	antitumor	PROPN
cusj-10967	145	31	immune	immune	ADJ
cusj-10967	145	32	activity	activity	NOUN
cusj-10967	145	33	through	through	ADP
cusj-10967	145	34	the	the	DET
cusj-10967	145	35	activity	activity	NOUN
cusj-10967	145	36	of	of	ADP
cusj-10967	145	37	viral	viral	ADJ
cusj-10967	145	38	vectors	vector	NOUN
cusj-10967	145	39	.	.	PUNCT
cusj-10967	146	1	roy	roy	PROPN
cusj-10967	146	2	and	and	CCONJ
cusj-10967	146	3	colleagues	colleague	NOUN
cusj-10967	146	4	furthered	further	VERB
cusj-10967	146	5	the	the	DET
cusj-10967	146	6	approach	approach	NOUN
cusj-10967	146	7	of	of	ADP
cusj-10967	146	8	engineering	engineering	NOUN
cusj-10967	146	9	ovs	ovs	NOUN
cusj-10967	146	10	that	that	PRON
cusj-10967	146	11	do	do	AUX
cusj-10967	146	12	not	not	PART
cusj-10967	146	13	rely	rely	VERB
cusj-10967	146	14	on	on	SCONJ
cusj-10967	146	15	division	division	NOUN
cusj-10967	146	16	to	to	PART
cusj-10967	146	17	be	be	AUX
cusj-10967	146	18	effective	effective	ADJ
cusj-10967	146	19	.	.	PUNCT
cusj-10967	147	1	the	the	DET
cusj-10967	147	2	researchers	researcher	NOUN
cusj-10967	147	3	developed	develop	VERB
cusj-10967	147	4	an	an	DET
cusj-10967	147	5	anti	anti	ADJ
cusj-10967	147	6	-	-	ADJ
cusj-10967	147	7	cancer	cancer	ADJ
cusj-10967	147	8	vaccine	vaccine	NOUN
cusj-10967	147	9	utilizing	utilize	VERB
cusj-10967	147	10	a	a	DET
cusj-10967	147	11	number	number	NOUN
cusj-10967	147	12	of	of	ADP
cusj-10967	147	13	viral	viral	ADJ
cusj-10967	147	14	vectors	vector	NOUN
cusj-10967	147	15	with	with	ADP
cusj-10967	147	16	antigenic	antigenic	ADJ
cusj-10967	147	17	peptides	peptide	NOUN
cusj-10967	147	18	.	.	PUNCT
cusj-10967	148	1	the	the	DET
cusj-10967	148	2	separation	separation	NOUN
cusj-10967	148	3	of	of	ADP
cusj-10967	148	4	these	these	DET
cusj-10967	148	5	peptide	peptide	ADJ
cusj-10967	148	6	components	component	NOUN
cusj-10967	148	7	allowed	allow	VERB
cusj-10967	148	8	for	for	ADP
cusj-10967	148	9	anticancer	anticancer	NOUN
cusj-10967	148	10	immunity	immunity	NOUN
cusj-10967	148	11	enhancement	enhancement	NOUN
cusj-10967	148	12	without	without	ADP
cusj-10967	148	13	requiring	require	VERB
cusj-10967	148	14	cell	cell	NOUN
cusj-10967	148	15	division.27	division.27	PROPN
cusj-10967	148	16	tian	tian	PROPN
cusj-10967	148	17	and	and	CCONJ
cusj-10967	148	18	colleagues	colleague	NOUN
cusj-10967	148	19	also	also	ADV
cusj-10967	148	20	developed	develop	VERB
cusj-10967	148	21	an	an	DET
cusj-10967	148	22	anti	anti	ADJ
cusj-10967	148	23	-	-	ADJ
cusj-10967	148	24	cancer	cancer	ADJ
cusj-10967	148	25	vaccine	vaccine	NOUN
cusj-10967	148	26	using	use	VERB
cusj-10967	148	27	a	a	DET
cusj-10967	148	28	herpes	herpe	NOUN
cusj-10967	148	29	simplex	simplex	NOUN
cusj-10967	148	30	virus	virus	NOUN
cusj-10967	148	31	to	to	PART
cusj-10967	148	32	carry	carry	VERB
cusj-10967	148	33	a	a	DET
cusj-10967	148	34	monoclonal	monoclonal	NOUN
cusj-10967	148	35	antibody.28	antibody.28	NOUN
cusj-10967	148	36	this	this	DET
cusj-10967	148	37	anti	anti	ADJ
cusj-10967	148	38	-	-	ADJ
cusj-10967	148	39	cancer	cancer	ADJ
cusj-10967	148	40	vaccine	vaccine	NOUN
cusj-10967	148	41	also	also	ADV
cusj-10967	148	42	downregulates	downregulate	VERB
cusj-10967	148	43	cell	cell	NOUN
cusj-10967	148	44	adhesion	adhesion	NOUN
cusj-10967	148	45	,	,	PUNCT
cusj-10967	148	46	reducing	reduce	VERB
cusj-10967	148	47	the	the	DET
cusj-10967	148	48	ability	ability	NOUN
cusj-10967	148	49	of	of	ADP
cusj-10967	148	50	a	a	DET
cusj-10967	148	51	tumor	tumor	NOUN
cusj-10967	148	52	to	to	PART
cusj-10967	148	53	exclude	exclude	VERB
cusj-10967	148	54	immune	immune	ADJ
cusj-10967	148	55	cells	cell	NOUN
cusj-10967	148	56	.	.	PUNCT
cusj-10967	149	1	priming	prime	VERB
cusj-10967	149	2	the	the	DET
cusj-10967	149	3	immune	immune	ADJ
cusj-10967	149	4	system	system	NOUN
cusj-10967	149	5	to	to	PART
cusj-10967	149	6	combat	combat	VERB
cusj-10967	149	7	cancer	cancer	NOUN
cusj-10967	149	8	cells	cell	NOUN
cusj-10967	149	9	has	have	VERB
cusj-10967	149	10	significant	significant	ADJ
cusj-10967	149	11	potential	potential	NOUN
cusj-10967	149	12	in	in	ADP
cusj-10967	149	13	reducing	reduce	VERB
cusj-10967	149	14	cancer	cancer	NOUN
cusj-10967	149	15	incidence	incidence	NOUN
cusj-10967	149	16	at	at	ADP
cusj-10967	149	17	an	an	DET
cusj-10967	149	18	earlier	early	ADJ
cusj-10967	149	19	stage	stage	NOUN
cusj-10967	149	20	of	of	ADP
cusj-10967	149	21	disease	disease	NOUN
cusj-10967	149	22	development	development	NOUN
cusj-10967	149	23	.	.	PUNCT
cusj-10967	150	1	additionally	additionally	ADV
cusj-10967	150	2	,	,	PUNCT
cusj-10967	150	3	increasing	increase	VERB
cusj-10967	150	4	the	the	DET
cusj-10967	150	5	natural	natural	ADJ
cusj-10967	150	6	immune	immune	ADJ
cusj-10967	150	7	response	response	NOUN
cusj-10967	150	8	to	to	ADP
cusj-10967	150	9	cancer	cancer	NOUN
cusj-10967	150	10	in	in	ADP
cusj-10967	150	11	individuals	individual	NOUN
cusj-10967	150	12	with	with	ADP
cusj-10967	150	13	a	a	DET
cusj-10967	150	14	predisposition	predisposition	NOUN
cusj-10967	150	15	to	to	ADP
cusj-10967	150	16	cancer	cancer	NOUN
cusj-10967	150	17	development	development	NOUN
cusj-10967	150	18	could	could	AUX
cusj-10967	150	19	improve	improve	VERB
cusj-10967	150	20	patient	patient	ADJ
cusj-10967	150	21	outcomes	outcome	NOUN
cusj-10967	150	22	.	.	PUNCT
cusj-10967	151	1	improving	improve	VERB
cusj-10967	151	2	immune	immune	ADJ
cusj-10967	151	3	memory	memory	NOUN
cusj-10967	151	4	through	through	ADP
cusj-10967	151	5	increasing	increase	VERB
cusj-10967	151	6	memory	memory	NOUN
cusj-10967	151	7	cell	cell	NOUN
cusj-10967	151	8	counts	count	NOUN
cusj-10967	151	9	or	or	CCONJ
cusj-10967	151	10	extending	extend	VERB
cusj-10967	151	11	memory	memory	NOUN
cusj-10967	151	12	cell	cell	NOUN
cusj-10967	151	13	survival	survival	NOUN
cusj-10967	151	14	also	also	ADV
cusj-10967	151	15	contributes	contribute	VERB
cusj-10967	151	16	to	to	ADP
cusj-10967	151	17	viral	viral	ADJ
cusj-10967	151	18	effectiveness	effectiveness	NOUN
cusj-10967	151	19	against	against	ADP
cusj-10967	151	20	slow	slow	ADV
cusj-10967	151	21	-	-	PUNCT
cusj-10967	151	22	growing	grow	VERB
cusj-10967	151	23	tumors	tumor	NOUN
cusj-10967	151	24	.	.	PUNCT
cusj-10967	152	1	as	as	SCONJ
cusj-10967	152	2	a	a	DET
cusj-10967	152	3	tumor	tumor	NOUN
cusj-10967	152	4	grows	grow	VERB
cusj-10967	152	5	,	,	PUNCT
cusj-10967	152	6	the	the	DET
cusj-10967	152	7	immune	immune	ADJ
cusj-10967	152	8	memory	memory	NOUN
cusj-10967	152	9	of	of	ADP
cusj-10967	152	10	that	that	DET
cusj-10967	152	11	cancer	cancer	NOUN
cusj-10967	152	12	type	type	NOUN
cusj-10967	152	13	could	could	AUX
cusj-10967	152	14	trigger	trigger	VERB
cusj-10967	152	15	a	a	DET
cusj-10967	152	16	response	response	NOUN
cusj-10967	152	17	and	and	CCONJ
cusj-10967	152	18	draw	draw	VERB
cusj-10967	152	19	immune	immune	ADJ
cusj-10967	152	20	cells	cell	NOUN
cusj-10967	152	21	to	to	ADP
cusj-10967	152	22	the	the	DET
cusj-10967	152	23	tumor	tumor	NOUN
cusj-10967	152	24	.	.	PUNCT
cusj-10967	153	1	thomas	thomas	PROPN
cusj-10967	153	2	and	and	CCONJ
cusj-10967	153	3	colleagues	colleague	NOUN
cusj-10967	153	4	developed	develop	VERB
cusj-10967	153	5	an	an	DET
cusj-10967	153	6	oncolytic	oncolytic	ADJ
cusj-10967	153	7	herpes	herpe	NOUN
cusj-10967	153	8	simplex	simplex	NOUN
cusj-10967	153	9	virus	virus	NOUN
cusj-10967	153	10	that	that	PRON
cusj-10967	153	11	improves	improve	VERB
cusj-10967	153	12	immune	immune	ADJ
cusj-10967	153	13	memory	memory	NOUN
cusj-10967	153	14	after	after	ADP
cusj-10967	153	15	responding	respond	VERB
cusj-10967	153	16	to	to	ADP
cusj-10967	153	17	tumor	tumor	NOUN
cusj-10967	153	18	cells.29	cells.29	PROPN
cusj-10967	153	19	the	the	DET
cusj-10967	153	20	researchers	researcher	NOUN
cusj-10967	153	21	achieved	achieve	VERB
cusj-10967	153	22	this	this	PRON
cusj-10967	153	23	by	by	ADP
cusj-10967	153	24	identifying	identify	VERB
cusj-10967	153	25	a	a	DET
cusj-10967	153	26	virus	virus	NOUN
cusj-10967	153	27	that	that	PRON
cusj-10967	153	28	demonstrated	demonstrate	VERB
cusj-10967	153	29	antitumor	antitumor	NOUN
cusj-10967	153	30	activity	activity	NOUN
cusj-10967	153	31	and	and	CCONJ
cusj-10967	153	32	expressed	express	VERB
cusj-10967	153	33	a	a	DET
cusj-10967	153	34	truncated	truncated	ADJ
cusj-10967	153	35	envelope	envelope	NOUN
cusj-10967	153	36	glycoprotein	glycoprotein	NOUN
cusj-10967	153	37	in	in	ADP
cusj-10967	153	38	the	the	DET
cusj-10967	153	39	virus	virus	NOUN
cusj-10967	153	40	.	.	PUNCT
cusj-10967	154	1	they	they	PRON
cusj-10967	154	2	found	find	VERB
cusj-10967	154	3	that	that	SCONJ
cusj-10967	154	4	the	the	DET
cusj-10967	154	5	antitumor	antitumor	PROPN
cusj-10967	154	6	activity	activity	NOUN
cusj-10967	154	7	of	of	ADP
cusj-10967	154	8	this	this	PRON
cusj-10967	154	9	ov	ov	PROPN
cusj-10967	154	10	leads	lead	VERB
cusj-10967	154	11	to	to	ADP
cusj-10967	154	12	the	the	DET
cusj-10967	154	13	activation	activation	NOUN
cusj-10967	154	14	of	of	ADP
cusj-10967	154	15	signaling	signal	VERB
cusj-10967	154	16	molecules	molecule	NOUN
cusj-10967	154	17	that	that	PRON
cusj-10967	154	18	cause	cause	VERB
cusj-10967	154	19	immune	immune	ADJ
cusj-10967	154	20	memory	memory	NOUN
cusj-10967	154	21	to	to	PART
cusj-10967	154	22	form	form	VERB
cusj-10967	154	23	via	via	ADP
cusj-10967	154	24	memory	memory	NOUN
cusj-10967	154	25	cells	cell	NOUN
cusj-10967	154	26	.	.	PUNCT
cusj-10967	155	1	slow	slow	ADV
cusj-10967	155	2	-	-	PUNCT
cusj-10967	155	3	growing	grow	VERB
cusj-10967	155	4	tumors	tumor	NOUN
cusj-10967	155	5	have	have	AUX
cusj-10967	155	6	gained	gain	VERB
cusj-10967	155	7	interest	interest	NOUN
cusj-10967	155	8	as	as	SCONJ
cusj-10967	155	9	their	their	PRON
cusj-10967	155	10	low	low	ADJ
cusj-10967	155	11	division	division	NOUN
cusj-10967	155	12	rate	rate	NOUN
cusj-10967	155	13	causes	cause	VERB
cusj-10967	155	14	ovs	ovs	NOUN
cusj-10967	155	15	that	that	PRON
cusj-10967	155	16	rely	rely	VERB
cusj-10967	155	17	on	on	ADP
cusj-10967	155	18	cell	cell	NOUN
cusj-10967	155	19	division	division	NOUN
cusj-10967	155	20	to	to	PART
cusj-10967	155	21	not	not	PART
cusj-10967	155	22	be	be	AUX
cusj-10967	155	23	as	as	ADV
cusj-10967	155	24	effective	effective	ADJ
cusj-10967	155	25	.	.	PUNCT
cusj-10967	156	1	while	while	SCONJ
cusj-10967	156	2	this	this	PRON
cusj-10967	156	3	is	be	AUX
cusj-10967	156	4	a	a	DET
cusj-10967	156	5	significant	significant	ADJ
cusj-10967	156	6	engineering	engineering	NOUN
cusj-10967	156	7	challenge	challenge	NOUN
cusj-10967	156	8	,	,	PUNCT
cusj-10967	156	9	recent	recent	ADJ
cusj-10967	156	10	studies	study	NOUN
cusj-10967	156	11	have	have	AUX
cusj-10967	156	12	shown	show	VERB
cusj-10967	156	13	that	that	SCONJ
cusj-10967	156	14	there	there	PRON
cusj-10967	156	15	are	be	VERB
cusj-10967	156	16	still	still	ADV
cusj-10967	156	17	methods	method	NOUN
cusj-10967	156	18	of	of	ADP
cusj-10967	156	19	overcoming	overcome	VERB
cusj-10967	156	20	or	or	CCONJ
cusj-10967	156	21	circumventing	circumvent	VERB
cusj-10967	156	22	the	the	DET
cusj-10967	156	23	low	low	ADJ
cusj-10967	156	24	division	division	NOUN
cusj-10967	156	25	rate	rate	NOUN
cusj-10967	156	26	.	.	PUNCT
cusj-10967	157	1	ovs	ovs	NOUN
cusj-10967	157	2	that	that	PRON
cusj-10967	157	3	create	create	VERB
cusj-10967	157	4	high	high	ADJ
cusj-10967	157	5	viral	viral	ADJ
cusj-10967	157	6	loads	load	NOUN
cusj-10967	157	7	without	without	ADP
cusj-10967	157	8	quickly	quickly	ADV
cusj-10967	157	9	lysing	lyse	VERB
cusj-10967	157	10	cancer	cancer	NOUN
cusj-10967	157	11	cells	cell	NOUN
cusj-10967	157	12	can	can	AUX
cusj-10967	157	13	gain	gain	VERB
cusj-10967	157	14	the	the	DET
cusj-10967	157	15	most	most	ADJ
cusj-10967	157	16	benefit	benefit	NOUN
cusj-10967	157	17	from	from	ADP
cusj-10967	157	18	each	each	DET
cusj-10967	157	19	cell	cell	NOUN
cusj-10967	157	20	division	division	NOUN
cusj-10967	157	21	in	in	ADP
cusj-10967	157	22	a	a	DET
cusj-10967	157	23	slow	slow	ADV
cusj-10967	157	24	-	-	PUNCT
cusj-10967	157	25	growing	grow	VERB
cusj-10967	157	26	tumor	tumor	NOUN
cusj-10967	157	27	.	.	PUNCT
cusj-10967	158	1	progress	progress	NOUN
cusj-10967	158	2	has	have	AUX
cusj-10967	158	3	also	also	ADV
cusj-10967	158	4	been	be	AUX
cusj-10967	158	5	made	make	VERB
cusj-10967	158	6	on	on	ADP
cusj-10967	158	7	the	the	DET
cusj-10967	158	8	development	development	NOUN
cusj-10967	158	9	of	of	ADP
cusj-10967	158	10	research	research	NOUN
cusj-10967	158	11	tools	tool	NOUN
cusj-10967	158	12	and	and	CCONJ
cusj-10967	158	13	earlystage	earlystage	NOUN
cusj-10967	158	14	mechanisms	mechanism	NOUN
cusj-10967	158	15	for	for	ADP
cusj-10967	158	16	treating	treat	VERB
cusj-10967	158	17	slow	slow	ADV
cusj-10967	158	18	-	-	PUNCT
cusj-10967	158	19	growing	grow	VERB
cusj-10967	158	20	tumors	tumor	NOUN
cusj-10967	158	21	.	.	PUNCT
cusj-10967	159	1	anti	anti	ADJ
cusj-10967	159	2	-	-	ADJ
cusj-10967	159	3	cancer	cancer	ADJ
cusj-10967	159	4	vaccines	vaccine	NOUN
cusj-10967	159	5	have	have	VERB
cusj-10967	159	6	the	the	DET
cusj-10967	159	7	potential	potential	NOUN
cusj-10967	159	8	to	to	PART
cusj-10967	159	9	develop	develop	VERB
cusj-10967	159	10	into	into	ADP
cusj-10967	159	11	clinical	clinical	ADJ
cusj-10967	159	12	treatments	treatment	NOUN
cusj-10967	159	13	.	.	PUNCT
cusj-10967	160	1	enhancing	enhance	VERB
cusj-10967	160	2	immune	immune	ADJ
cusj-10967	160	3	memory	memory	NOUN
cusj-10967	160	4	via	via	ADP
cusj-10967	160	5	ov	ov	PROPN
cusj-10967	160	6	action	action	NOUN
cusj-10967	160	7	also	also	ADV
cusj-10967	160	8	holds	hold	VERB
cusj-10967	160	9	potential	potential	NOUN
cusj-10967	160	10	for	for	ADP
cusj-10967	160	11	treating	treat	VERB
cusj-10967	160	12	slowgrowing	slowgrowe	VERB
cusj-10967	160	13	tumors	tumor	NOUN
cusj-10967	160	14	through	through	ADP
cusj-10967	160	15	a	a	DET
cusj-10967	160	16	natural	natural	ADJ
cusj-10967	160	17	,	,	PUNCT
cusj-10967	160	18	long	long	ADJ
cusj-10967	160	19	-	-	PUNCT
cusj-10967	160	20	term	term	NOUN
cusj-10967	160	21	immune	immune	ADJ
cusj-10967	160	22	amplification	amplification	NOUN
cusj-10967	160	23	.	.	PUNCT
cusj-10967	161	1	tumor	tumor	NOUN
cusj-10967	161	2	targeting	target	VERB
cusj-10967	161	3	specificity	specificity	NOUN
cusj-10967	161	4	as	as	SCONJ
cusj-10967	161	5	demonstrated	demonstrate	VERB
cusj-10967	161	6	by	by	ADP
cusj-10967	161	7	t	t	PROPN
cusj-10967	161	8	-	-	PUNCT
cusj-10967	161	9	vec	vec	PROPN
cusj-10967	161	10	,	,	PUNCT
cusj-10967	161	11	there	there	PRON
cusj-10967	161	12	is	be	VERB
cusj-10967	161	13	a	a	DET
cusj-10967	161	14	need	need	NOUN
cusj-10967	161	15	to	to	PART
cusj-10967	161	16	improve	improve	VERB
cusj-10967	161	17	the	the	DET
cusj-10967	161	18	targeting	target	VERB
cusj-10967	161	19	specificity	specificity	NOUN
cusj-10967	161	20	of	of	ADP
cusj-10967	161	21	ovs	ovs	NOUN
cusj-10967	161	22	to	to	PART
cusj-10967	161	23	infect	infect	VERB
cusj-10967	161	24	tumor	tumor	NOUN
cusj-10967	161	25	cells	cell	NOUN
cusj-10967	161	26	primarily	primarily	ADV
cusj-10967	161	27	or	or	CCONJ
cusj-10967	161	28	almost	almost	ADV
cusj-10967	161	29	exclusively	exclusively	ADV
cusj-10967	161	30	.	.	PUNCT
cusj-10967	162	1	this	this	PRON
cusj-10967	162	2	could	could	AUX
cusj-10967	162	3	effectively	effectively	ADV
cusj-10967	162	4	reduce	reduce	VERB
cusj-10967	162	5	any	any	DET
cusj-10967	162	6	possible	possible	ADJ
cusj-10967	162	7	systemic	systemic	ADJ
cusj-10967	162	8	effect	effect	NOUN
cusj-10967	162	9	of	of	ADP
cusj-10967	162	10	ov	ov	PROPN
cusj-10967	162	11	therapy	therapy	NOUN
cusj-10967	162	12	and	and	CCONJ
cusj-10967	162	13	improve	improve	VERB
cusj-10967	162	14	patient	patient	ADJ
cusj-10967	162	15	safety	safety	NOUN
cusj-10967	162	16	.	.	PUNCT
cusj-10967	163	1	one	one	NUM
cusj-10967	163	2	approach	approach	NOUN
cusj-10967	163	3	that	that	PRON
cusj-10967	163	4	has	have	AUX
cusj-10967	163	5	shown	show	VERB
cusj-10967	163	6	significant	significant	ADJ
cusj-10967	163	7	potential	potential	NOUN
cusj-10967	163	8	in	in	ADP
cusj-10967	163	9	facilitating	facilitate	VERB
cusj-10967	163	10	improvements	improvement	NOUN
cusj-10967	163	11	in	in	ADP
cusj-10967	163	12	infection	infection	NOUN
cusj-10967	163	13	specificity	specificity	NOUN
cusj-10967	163	14	is	be	AUX
cusj-10967	163	15	the	the	DET
cusj-10967	163	16	utilization	utilization	NOUN
cusj-10967	163	17	of	of	ADP
cusj-10967	163	18	biochemical	biochemical	ADJ
cusj-10967	163	19	signaling	signal	VERB
cusj-10967	163	20	pathway	pathway	NOUN
cusj-10967	163	21	components	component	NOUN
cusj-10967	163	22	as	as	ADP
cusj-10967	163	23	markers	marker	NOUN
cusj-10967	163	24	for	for	ADP
cusj-10967	163	25	ovs	ovs	NOUN
cusj-10967	163	26	.	.	PUNCT
cusj-10967	164	1	biochemical	biochemical	ADJ
cusj-10967	164	2	signaling	signal	VERB
cusj-10967	164	3	pathways	pathway	NOUN
cusj-10967	164	4	play	play	VERB
cusj-10967	164	5	a	a	DET
cusj-10967	164	6	significant	significant	ADJ
cusj-10967	164	7	role	role	NOUN
cusj-10967	164	8	in	in	ADP
cusj-10967	164	9	the	the	DET
cusj-10967	164	10	regulation	regulation	NOUN
cusj-10967	164	11	of	of	ADP
cusj-10967	164	12	tissue	tissue	NOUN
cusj-10967	164	13	maintenance	maintenance	NOUN
cusj-10967	164	14	and	and	CCONJ
cusj-10967	164	15	cell	cell	NOUN
cusj-10967	164	16	division	division	NOUN
cusj-10967	164	17	.	.	PUNCT
cusj-10967	165	1	any	any	DET
cusj-10967	165	2	imbalance	imbalance	NOUN
cusj-10967	165	3	or	or	CCONJ
cusj-10967	165	4	dysregulation	dysregulation	NOUN
cusj-10967	165	5	in	in	ADP
cusj-10967	165	6	these	these	DET
cusj-10967	165	7	signaling	signal	VERB
cusj-10967	165	8	pathways	pathway	NOUN
cusj-10967	165	9	can	can	AUX
cusj-10967	165	10	lead	lead	VERB
cusj-10967	165	11	to	to	ADP
cusj-10967	165	12	the	the	DET
cusj-10967	165	13	development	development	NOUN
cusj-10967	165	14	of	of	ADP
cusj-10967	165	15	cancer	cancer	NOUN
cusj-10967	165	16	.	.	PUNCT
cusj-10967	166	1	ligand	ligand	NOUN
cusj-10967	166	2	-	-	PUNCT
cusj-10967	166	3	receptor	receptor	NOUN
cusj-10967	166	4	binding	bind	VERB
cusj-10967	166	5	interactions	interaction	NOUN
cusj-10967	166	6	also	also	ADV
cusj-10967	166	7	provide	provide	VERB
cusj-10967	166	8	an	an	DET
cusj-10967	166	9	opportunity	opportunity	NOUN
cusj-10967	166	10	for	for	ADP
cusj-10967	166	11	improving	improve	VERB
cusj-10967	166	12	tumor	tumor	NOUN
cusj-10967	166	13	targeting	target	VERB
cusj-10967	166	14	specificity	specificity	NOUN
cusj-10967	166	15	by	by	ADP
cusj-10967	166	16	taking	take	VERB
cusj-10967	166	17	advantage	advantage	NOUN
cusj-10967	166	18	of	of	ADP
cusj-10967	166	19	a	a	DET
cusj-10967	166	20	signaling	signal	VERB
cusj-10967	166	21	pathway	pathway	NOUN
cusj-10967	166	22	that	that	PRON
cusj-10967	166	23	is	be	AUX
cusj-10967	166	24	dysregulated	dysregulate	VERB
cusj-10967	166	25	to	to	PART
cusj-10967	166	26	facilitate	facilitate	VERB
cusj-10967	166	27	localization	localization	NOUN
cusj-10967	166	28	by	by	ADP
cusj-10967	166	29	ovs.30	ovs.30	PRON
cusj-10967	166	30	there	there	PRON
cusj-10967	166	31	are	be	VERB
cusj-10967	166	32	many	many	ADJ
cusj-10967	166	33	pathways	pathway	NOUN
cusj-10967	166	34	that	that	PRON
cusj-10967	166	35	have	have	VERB
cusj-10967	166	36	the	the	DET
cusj-10967	166	37	potential	potential	NOUN
cusj-10967	166	38	to	to	PART
cusj-10967	166	39	be	be	AUX
cusj-10967	166	40	utilized	utilize	VERB
cusj-10967	166	41	as	as	ADP
cusj-10967	166	42	the	the	DET
cusj-10967	166	43	basis	basis	NOUN
cusj-10967	166	44	of	of	ADP
cusj-10967	166	45	a	a	DET
cusj-10967	166	46	tumor	tumor	NOUN
cusj-10967	166	47	-	-	PUNCT
cusj-10967	166	48	targeting	target	VERB
cusj-10967	166	49	system	system	NOUN
cusj-10967	166	50	.	.	PUNCT
cusj-10967	167	1	one	one	NUM
cusj-10967	167	2	such	such	ADJ
cusj-10967	167	3	ligand	ligand	NOUN
cusj-10967	167	4	-	-	PUNCT
cusj-10967	167	5	receptor	receptor	NOUN
cusj-10967	167	6	interaction	interaction	NOUN
cusj-10967	167	7	that	that	PRON
cusj-10967	167	8	has	have	AUX
cusj-10967	167	9	been	be	AUX
cusj-10967	167	10	studied	study	VERB
cusj-10967	167	11	extensively	extensively	ADV
cusj-10967	167	12	is	be	AUX
cusj-10967	167	13	that	that	SCONJ
cusj-10967	167	14	between	between	ADP
cusj-10967	167	15	c	c	NOUN
cusj-10967	167	16	-	-	PUNCT
cusj-10967	167	17	c	c	PROPN
cusj-10967	167	18	chemokine	chemokine	PROPN
cusj-10967	167	19	ligand	ligand	NOUN
cusj-10967	167	20	5	5	NUM
cusj-10967	167	21	(	(	PUNCT
cusj-10967	167	22	ccl5	ccl5	PROPN
cusj-10967	167	23	)	)	PUNCT
cusj-10967	167	24	and	and	CCONJ
cusj-10967	167	25	c	c	X
cusj-10967	167	26	-	-	PUNCT
cusj-10967	167	27	c	c	VERB
cusj-10967	167	28	chemokine	chemokine	ADJ
cusj-10967	167	29	receptor	receptor	NOUN
cusj-10967	167	30	type	type	NOUN
cusj-10967	167	31	5	5	NUM
cusj-10967	167	32	(	(	PUNCT
cusj-10967	167	33	ccr5	ccr5	PROPN
cusj-10967	167	34	)	)	PUNCT
cusj-10967	167	35	.	.	PUNCT
cusj-10967	168	1	in	in	ADP
cusj-10967	168	2	many	many	ADJ
cusj-10967	168	3	types	type	NOUN
cusj-10967	168	4	of	of	ADP
cusj-10967	168	5	cancer	cancer	NOUN
cusj-10967	168	6	,	,	PUNCT
cusj-10967	168	7	the	the	DET
cusj-10967	168	8	ccl5	ccl5	PROPN
cusj-10967	168	9	/	/	SYM
cusj-10967	168	10	ccr5	ccr5	PROPN
cusj-10967	168	11	ligand	ligand	NOUN
cusj-10967	168	12	-	-	PUNCT
cusj-10967	168	13	receptor	receptor	NOUN
cusj-10967	168	14	interaction	interaction	NOUN
cusj-10967	168	15	functions	function	NOUN
cusj-10967	168	16	improperly	improperly	ADV
cusj-10967	168	17	and	and	CCONJ
cusj-10967	168	18	contributes	contribute	VERB
cusj-10967	168	19	to	to	ADP
cusj-10967	168	20	tumor	tumor	NOUN
cusj-10967	168	21	growth	growth	NOUN
cusj-10967	168	22	and	and	CCONJ
cusj-10967	168	23	metastasis.31	metastasis.31	PROPN
cusj-10967	168	24	li	li	PROPN
cusj-10967	168	25	and	and	CCONJ
cusj-10967	168	26	colleagues	colleague	NOUN
cusj-10967	168	27	developed	develop	VERB
cusj-10967	168	28	a	a	DET
cusj-10967	168	29	pair	pair	NOUN
cusj-10967	168	30	of	of	ADP
cusj-10967	168	31	ovs	ovs	NOUN
cusj-10967	168	32	that	that	PRON
cusj-10967	168	33	upregulate	upregulate	VERB
cusj-10967	168	34	ccl5	ccl5	NOUN
cusj-10967	168	35	in	in	ADP
cusj-10967	168	36	infected	infected	ADJ
cusj-10967	168	37	tumor	tumor	NOUN
cusj-10967	168	38	cells	cell	NOUN
cusj-10967	168	39	and	and	CCONJ
cusj-10967	168	40	upregulate	upregulate	VERB
cusj-10967	168	41	ccr5	ccr5	NOUN
cusj-10967	168	42	expression	expression	NOUN
cusj-10967	168	43	in	in	ADP
cusj-10967	168	44	nk	nk	PROPN
cusj-10967	168	45	cells	cell	NOUN
cusj-10967	168	46	,	,	PUNCT
cusj-10967	168	47	respectively	respectively	ADV
cusj-10967	168	48	.	.	PUNCT
cusj-10967	169	1	each	each	PRON
cusj-10967	169	2	of	of	ADP
cusj-10967	169	3	these	these	DET
cusj-10967	169	4	components	component	NOUN
cusj-10967	169	5	individually	individually	ADV
cusj-10967	169	6	increased	increase	VERB
cusj-10967	169	7	antitumor	antitumor	PROPN
cusj-10967	169	8	effectiveness	effectiveness	NOUN
cusj-10967	169	9	,	,	PUNCT
cusj-10967	169	10	and	and	CCONJ
cusj-10967	169	11	the	the	DET
cusj-10967	169	12	combined	combine	VERB
cusj-10967	169	13	treatment	treatment	NOUN
cusj-10967	169	14	system	system	NOUN
cusj-10967	169	15	was	be	AUX
cusj-10967	169	16	more	more	ADV
cusj-10967	169	17	effective	effective	ADJ
cusj-10967	169	18	than	than	ADP
cusj-10967	169	19	either	either	DET
cusj-10967	169	20	columbia	columbia	PROPN
cusj-10967	169	21	undergraduate	undergraduate	PROPN
cusj-10967	169	22	science	science	PROPN
cusj-10967	169	23	journal	journal	PROPN
cusj-10967	169	24	vol	vol	NOUN
cusj-10967	169	25	.	.	PROPN
cusj-10967	169	26	18	18	NUM
cusj-10967	169	27	,	,	PUNCT
cusj-10967	169	28	2024	2024	NUM
cusj-10967	169	29	manjila	manjila	PROPN
cusj-10967	169	30	component	component	NOUN
cusj-10967	169	31	alone	alone	ADV
cusj-10967	169	32	.	.	PUNCT
cusj-10967	170	1	the	the	DET
cusj-10967	170	2	result	result	NOUN
cusj-10967	170	3	of	of	ADP
cusj-10967	170	4	this	this	DET
cusj-10967	170	5	bilateral	bilateral	ADJ
cusj-10967	170	6	oncolytic	oncolytic	NOUN
cusj-10967	170	7	virotherapy	virotherapy	NOUN
cusj-10967	170	8	was	be	AUX
cusj-10967	170	9	the	the	DET
cusj-10967	170	10	establishment	establishment	NOUN
cusj-10967	170	11	of	of	ADP
cusj-10967	170	12	a	a	DET
cusj-10967	170	13	tumor	tumor	NOUN
cusj-10967	170	14	-	-	PUNCT
cusj-10967	170	15	targeting	target	VERB
cusj-10967	170	16	system	system	NOUN
cusj-10967	170	17	which	which	PRON
cusj-10967	170	18	led	lead	VERB
cusj-10967	170	19	to	to	ADP
cusj-10967	170	20	an	an	DET
cusj-10967	170	21	improved	improved	ADJ
cusj-10967	170	22	antitumor	antitumor	PROPN
cusj-10967	170	23	effect	effect	NOUN
cusj-10967	170	24	.	.	PUNCT
cusj-10967	171	1	nk	nk	PROPN
cusj-10967	171	2	cells	cell	NOUN
cusj-10967	171	3	were	be	AUX
cusj-10967	171	4	also	also	ADV
cusj-10967	171	5	more	more	ADV
cusj-10967	171	6	effectively	effectively	ADV
cusj-10967	171	7	able	able	ADJ
cusj-10967	171	8	to	to	PART
cusj-10967	171	9	target	target	VERB
cusj-10967	171	10	and	and	CCONJ
cusj-10967	171	11	destroy	destroy	VERB
cusj-10967	171	12	the	the	DET
cusj-10967	171	13	corresponding	correspond	VERB
cusj-10967	171	14	cancer	cancer	NOUN
cusj-10967	171	15	cells.32	cells.32	VERB
cusj-10967	171	16	additionally	additionally	ADV
cusj-10967	171	17	,	,	PUNCT
cusj-10967	171	18	the	the	DET
cusj-10967	171	19	ov	ov	PROPN
cusj-10967	171	20	engineered	engineer	VERB
cusj-10967	171	21	to	to	PART
cusj-10967	171	22	cause	cause	VERB
cusj-10967	171	23	ccl5	ccl5	NOUN
cusj-10967	171	24	expression	expression	NOUN
cusj-10967	171	25	did	do	AUX
cusj-10967	171	26	not	not	PART
cusj-10967	171	27	infect	infect	VERB
cusj-10967	171	28	nk	nk	PROPN
cusj-10967	171	29	cells	cell	NOUN
cusj-10967	171	30	in	in	ADP
cusj-10967	171	31	significant	significant	ADJ
cusj-10967	171	32	numbers	number	NOUN
cusj-10967	171	33	.	.	PUNCT
cusj-10967	172	1	this	this	PRON
cusj-10967	172	2	is	be	AUX
cusj-10967	172	3	an	an	DET
cusj-10967	172	4	important	important	ADJ
cusj-10967	172	5	finding	finding	NOUN
cusj-10967	172	6	since	since	SCONJ
cusj-10967	172	7	nk	nk	PROPN
cusj-10967	172	8	cells	cell	NOUN
cusj-10967	172	9	with	with	ADP
cusj-10967	172	10	ccr5	ccr5	NOUN
cusj-10967	172	11	expression	expression	NOUN
cusj-10967	172	12	would	would	AUX
cusj-10967	172	13	be	be	AUX
cusj-10967	172	14	drawn	draw	VERB
cusj-10967	172	15	to	to	ADP
cusj-10967	172	16	nk	nk	PROPN
cusj-10967	172	17	cells	cell	NOUN
cusj-10967	172	18	with	with	ADP
cusj-10967	172	19	ccl5	ccl5	PROPN
cusj-10967	172	20	expression	expression	NOUN
cusj-10967	172	21	,	,	PUNCT
cusj-10967	172	22	rather	rather	ADV
cusj-10967	172	23	than	than	ADP
cusj-10967	172	24	the	the	DET
cusj-10967	172	25	tumor	tumor	NOUN
cusj-10967	172	26	cells	cell	NOUN
cusj-10967	172	27	.	.	PUNCT
cusj-10967	173	1	researchers	researcher	NOUN
cusj-10967	173	2	have	have	AUX
cusj-10967	173	3	explored	explore	VERB
cusj-10967	173	4	additional	additional	ADJ
cusj-10967	173	5	avenues	avenue	NOUN
cusj-10967	173	6	to	to	PART
cusj-10967	173	7	improve	improve	VERB
cusj-10967	173	8	target	target	NOUN
cusj-10967	173	9	specificity	specificity	NOUN
cusj-10967	173	10	.	.	PUNCT
cusj-10967	174	1	vijayakumar	vijayakumar	NOUN
cusj-10967	174	2	and	and	CCONJ
cusj-10967	174	3	colleagues	colleague	NOUN
cusj-10967	174	4	engineered	engineer	VERB
cusj-10967	174	5	an	an	DET
cusj-10967	174	6	oncolytic	oncolytic	ADJ
cusj-10967	174	7	newcastle	newcastle	PROPN
cusj-10967	174	8	disease	disease	PROPN
cusj-10967	174	9	virus	virus	NOUN
cusj-10967	174	10	to	to	PART
cusj-10967	174	11	deliver	deliver	VERB
cusj-10967	174	12	immunotherapeutic	immunotherapeutic	ADJ
cusj-10967	174	13	molecules	molecule	NOUN
cusj-10967	174	14	to	to	ADP
cusj-10967	174	15	tumors	tumor	NOUN
cusj-10967	174	16	,	,	PUNCT
cusj-10967	174	17	eliciting	elicit	VERB
cusj-10967	174	18	a	a	DET
cusj-10967	174	19	targeted	target	VERB
cusj-10967	174	20	antitumor	antitumor	PROPN
cusj-10967	174	21	response.33	response.33	NOUN
cusj-10967	174	22	zuo	zuo	PROPN
cusj-10967	174	23	and	and	CCONJ
cusj-10967	174	24	colleagues	colleague	NOUN
cusj-10967	174	25	developed	develop	VERB
cusj-10967	174	26	an	an	DET
cusj-10967	174	27	oncolytic	oncolytic	ADJ
cusj-10967	174	28	vaccinia	vaccinia	NOUN
cusj-10967	174	29	virus	virus	NOUN
cusj-10967	174	30	that	that	PRON
cusj-10967	174	31	encodes	encode	VERB
cusj-10967	174	32	for	for	ADP
cusj-10967	174	33	a	a	DET
cusj-10967	174	34	singlechain	singlechain	ADJ
cusj-10967	174	35	variable	variable	ADJ
cusj-10967	174	36	fragment	fragment	NOUN
cusj-10967	174	37	that	that	PRON
cusj-10967	174	38	targets	target	VERB
cusj-10967	174	39	immune	immune	ADJ
cusj-10967	174	40	cells.34	cells.34	NOUN
cusj-10967	174	41	wang	wang	PROPN
cusj-10967	174	42	and	and	CCONJ
cusj-10967	174	43	colleagues	colleague	NOUN
cusj-10967	174	44	created	create	VERB
cusj-10967	174	45	an	an	DET
cusj-10967	174	46	oncolytic	oncolytic	ADJ
cusj-10967	174	47	vaccinia	vaccinia	NOUN
cusj-10967	174	48	virus	virus	NOUN
cusj-10967	174	49	that	that	PRON
cusj-10967	174	50	inhibits	inhibit	VERB
cusj-10967	174	51	pd-1	pd-1	ADP
cusj-10967	174	52	,	,	PUNCT
cusj-10967	174	53	an	an	DET
cusj-10967	174	54	immunosuppressive	immunosuppressive	ADJ
cusj-10967	174	55	signaling	signal	VERB
cusj-10967	174	56	molecule	molecule	NOUN
cusj-10967	174	57	,	,	PUNCT
cusj-10967	174	58	and	and	CCONJ
cusj-10967	174	59	elicits	elicit	VERB
cusj-10967	174	60	a	a	DET
cusj-10967	174	61	cancer	cancer	NOUN
cusj-10967	174	62	-	-	PUNCT
cusj-10967	174	63	specific	specific	ADJ
cusj-10967	174	64	immune	immune	ADJ
cusj-10967	174	65	response.35	response.35	NOUN
cusj-10967	174	66	wu	wu	PROPN
cusj-10967	174	67	and	and	CCONJ
cusj-10967	174	68	colleagues	colleague	NOUN
cusj-10967	174	69	engineered	engineer	VERB
cusj-10967	174	70	an	an	DET
cusj-10967	174	71	oncolytic	oncolytic	ADJ
cusj-10967	174	72	vesicular	vesicular	ADJ
cusj-10967	174	73	stomatitis	stomatitis	NOUN
cusj-10967	174	74	virus	virus	NOUN
cusj-10967	174	75	that	that	PRON
cusj-10967	174	76	also	also	ADV
cusj-10967	174	77	inhibits	inhibit	VERB
cusj-10967	174	78	pd-1	pd-1	ADP
cusj-10967	174	79	,	,	PUNCT
cusj-10967	174	80	causing	cause	VERB
cusj-10967	174	81	an	an	DET
cusj-10967	174	82	antitumor	antitumor	PROPN
cusj-10967	174	83	effect.36	effect.36	PROPN
cusj-10967	174	84	walton	walton	PROPN
cusj-10967	174	85	and	and	CCONJ
cusj-10967	174	86	colleagues	colleague	NOUN
cusj-10967	174	87	developed	develop	VERB
cusj-10967	174	88	an	an	DET
cusj-10967	174	89	oncolytic	oncolytic	ADJ
cusj-10967	174	90	poliovirus	poliovirus	NOUN
cusj-10967	174	91	that	that	PRON
cusj-10967	174	92	proliferates	proliferate	VERB
cusj-10967	174	93	rapidly	rapidly	ADV
cusj-10967	174	94	,	,	PUNCT
cusj-10967	174	95	evades	evade	VERB
cusj-10967	174	96	immune	immune	ADJ
cusj-10967	174	97	response	response	NOUN
cusj-10967	174	98	,	,	PUNCT
cusj-10967	174	99	and	and	CCONJ
cusj-10967	174	100	is	be	AUX
cusj-10967	174	101	cytotoxic	cytotoxic	ADJ
cusj-10967	174	102	to	to	ADP
cusj-10967	174	103	infected	infect	VERB
cusj-10967	174	104	cancer	cancer	NOUN
cusj-10967	174	105	cells	cell	NOUN
cusj-10967	174	106	to	to	PART
cusj-10967	174	107	treat	treat	VERB
cusj-10967	174	108	glioblastoma	glioblastoma	NOUN
cusj-10967	174	109	,	,	PUNCT
cusj-10967	174	110	an	an	DET
cusj-10967	174	111	aggressive	aggressive	ADJ
cusj-10967	174	112	brain	brain	NOUN
cusj-10967	174	113	cancer.37	cancer.37	NOUN
cusj-10967	174	114	these	these	DET
cusj-10967	174	115	studies	study	NOUN
cusj-10967	174	116	utilize	utilize	VERB
cusj-10967	174	117	different	different	ADJ
cusj-10967	174	118	structural	structural	ADJ
cusj-10967	174	119	interactions	interaction	NOUN
cusj-10967	174	120	and	and	CCONJ
cusj-10967	174	121	signaling	signal	VERB
cusj-10967	174	122	pathways	pathway	NOUN
cusj-10967	174	123	to	to	PART
cusj-10967	174	124	effectively	effectively	ADV
cusj-10967	174	125	target	target	VERB
cusj-10967	174	126	tumors	tumor	NOUN
cusj-10967	174	127	and	and	CCONJ
cusj-10967	174	128	combat	combat	NOUN
cusj-10967	174	129	cancer	cancer	NOUN
cusj-10967	174	130	cells	cell	NOUN
cusj-10967	174	131	.	.	PUNCT
cusj-10967	175	1	triple	triple	ADJ
cusj-10967	175	2	-	-	PUNCT
cusj-10967	175	3	negative	negative	ADJ
cusj-10967	175	4	breast	breast	NOUN
cusj-10967	175	5	cancer	cancer	NOUN
cusj-10967	175	6	is	be	AUX
cusj-10967	175	7	very	very	ADV
cusj-10967	175	8	aggressive	aggressive	ADJ
cusj-10967	175	9	and	and	CCONJ
cusj-10967	175	10	difficult	difficult	ADJ
cusj-10967	175	11	to	to	PART
cusj-10967	175	12	treat	treat	VERB
cusj-10967	175	13	.	.	PUNCT
cusj-10967	176	1	ovs	ovs	PROPN
cusj-10967	176	2	engineered	engineer	VERB
cusj-10967	176	3	to	to	PART
cusj-10967	176	4	take	take	VERB
cusj-10967	176	5	advantage	advantage	NOUN
cusj-10967	176	6	of	of	ADP
cusj-10967	176	7	signaling	signal	VERB
cusj-10967	176	8	pathways	pathway	NOUN
cusj-10967	176	9	specific	specific	ADJ
cusj-10967	176	10	to	to	ADP
cusj-10967	176	11	triple	triple	ADJ
cusj-10967	176	12	-	-	PUNCT
cusj-10967	176	13	negative	negative	ADJ
cusj-10967	176	14	breast	breast	NOUN
cusj-10967	176	15	cancer	cancer	NOUN
cusj-10967	176	16	can	can	AUX
cusj-10967	176	17	demonstrate	demonstrate	VERB
cusj-10967	176	18	infection	infection	NOUN
cusj-10967	176	19	specificity	specificity	NOUN
cusj-10967	176	20	while	while	SCONJ
cusj-10967	176	21	also	also	ADV
cusj-10967	176	22	being	be	AUX
cusj-10967	176	23	more	more	ADV
cusj-10967	176	24	effective	effective	ADJ
cusj-10967	176	25	.	.	PUNCT
cusj-10967	177	1	rodriguez	rodriguez	PROPN
cusj-10967	177	2	stewart	stewart	PROPN
cusj-10967	177	3	and	and	CCONJ
cusj-10967	177	4	colleagues	colleague	NOUN
cusj-10967	177	5	developed	develop	VERB
cusj-10967	177	6	an	an	DET
cusj-10967	177	7	oncolytic	oncolytic	ADJ
cusj-10967	177	8	reovirus	reovirus	NOUN
cusj-10967	177	9	that	that	PRON
cusj-10967	177	10	activated	activate	VERB
cusj-10967	177	11	the	the	DET
cusj-10967	177	12	caspase	caspase	NOUN
cusj-10967	177	13	-	-	PUNCT
cusj-10967	177	14	mediated	mediate	VERB
cusj-10967	177	15	apoptosis	apoptosis	NOUN
cusj-10967	177	16	signaling	signal	VERB
cusj-10967	177	17	pathway	pathway	NOUN
cusj-10967	177	18	in	in	ADP
cusj-10967	177	19	a	a	DET
cusj-10967	177	20	novel	novel	NOUN
cusj-10967	177	21	manner.38	manner.38	NOUN
cusj-10967	177	22	the	the	DET
cusj-10967	177	23	caspase	caspase	NOUN
cusj-10967	177	24	pathway	pathway	NOUN
cusj-10967	177	25	involves	involve	VERB
cusj-10967	177	26	a	a	DET
cusj-10967	177	27	series	series	NOUN
cusj-10967	177	28	of	of	ADP
cusj-10967	177	29	caspase	caspase	PROPN
cusj-10967	177	30	signals	signal	VERB
cusj-10967	177	31	that	that	PRON
cusj-10967	177	32	end	end	VERB
cusj-10967	177	33	with	with	ADP
cusj-10967	177	34	caspase-3	caspase-3	NUM
cusj-10967	177	35	,	,	PUNCT
cusj-10967	177	36	triggering	trigger	VERB
cusj-10967	177	37	apoptosis	apoptosis	NOUN
cusj-10967	177	38	of	of	ADP
cusj-10967	177	39	the	the	DET
cusj-10967	177	40	cell	cell	NOUN
cusj-10967	177	41	.	.	PUNCT
cusj-10967	178	1	the	the	DET
cusj-10967	178	2	researchers	researcher	NOUN
cusj-10967	178	3	found	find	VERB
cusj-10967	178	4	that	that	SCONJ
cusj-10967	178	5	the	the	DET
cusj-10967	178	6	caspase	caspase	PROPN
cusj-10967	178	7	pathway	pathway	NOUN
cusj-10967	178	8	was	be	AUX
cusj-10967	178	9	activated	activate	VERB
cusj-10967	178	10	but	but	CCONJ
cusj-10967	178	11	caspase-3	caspase-3	NUM
cusj-10967	178	12	was	be	AUX
cusj-10967	178	13	not	not	PART
cusj-10967	178	14	,	,	PUNCT
cusj-10967	178	15	indicating	indicate	VERB
cusj-10967	178	16	that	that	SCONJ
cusj-10967	178	17	some	some	DET
cusj-10967	178	18	other	other	ADJ
cusj-10967	178	19	signaling	signal	VERB
cusj-10967	178	20	mechanism	mechanism	NOUN
cusj-10967	178	21	was	be	AUX
cusj-10967	178	22	responsible	responsible	ADJ
cusj-10967	178	23	for	for	ADP
cusj-10967	178	24	apoptosis	apoptosis	NOUN
cusj-10967	178	25	of	of	ADP
cusj-10967	178	26	tumor	tumor	NOUN
cusj-10967	178	27	cells.38	cells.38	NOUN
cusj-10967	178	28	this	this	DET
cusj-10967	178	29	difference	difference	NOUN
cusj-10967	178	30	in	in	ADP
cusj-10967	178	31	signaling	signal	VERB
cusj-10967	178	32	pathway	pathway	NOUN
cusj-10967	178	33	activity	activity	NOUN
cusj-10967	178	34	may	may	AUX
cusj-10967	178	35	explain	explain	VERB
cusj-10967	178	36	why	why	SCONJ
cusj-10967	178	37	the	the	DET
cusj-10967	178	38	tumor	tumor	NOUN
cusj-10967	178	39	cells	cell	NOUN
cusj-10967	178	40	were	be	AUX
cusj-10967	178	41	affected	affect	VERB
cusj-10967	178	42	with	with	ADP
cusj-10967	178	43	specificity	specificity	NOUN
cusj-10967	178	44	while	while	SCONJ
cusj-10967	178	45	also	also	ADV
cusj-10967	178	46	causing	cause	VERB
cusj-10967	178	47	apoptosis	apoptosis	NOUN
cusj-10967	178	48	.	.	PUNCT
cusj-10967	179	1	additionally	additionally	ADV
cusj-10967	179	2	,	,	PUNCT
cusj-10967	179	3	this	this	DET
cusj-10967	179	4	study	study	NOUN
cusj-10967	179	5	indicates	indicate	VERB
cusj-10967	179	6	that	that	SCONJ
cusj-10967	179	7	variations	variation	NOUN
cusj-10967	179	8	of	of	ADP
cusj-10967	179	9	previously	previously	ADV
cusj-10967	179	10	understood	understand	VERB
cusj-10967	179	11	signaling	signal	VERB
cusj-10967	179	12	pathways	pathway	NOUN
cusj-10967	179	13	may	may	AUX
cusj-10967	179	14	potentially	potentially	ADV
cusj-10967	179	15	facilitate	facilitate	VERB
cusj-10967	179	16	the	the	DET
cusj-10967	179	17	discovery	discovery	NOUN
cusj-10967	179	18	or	or	CCONJ
cusj-10967	179	19	design	design	NOUN
cusj-10967	179	20	of	of	ADP
cusj-10967	179	21	other	other	ADJ
cusj-10967	179	22	ovs	ovs	NOUN
cusj-10967	179	23	with	with	ADP
cusj-10967	179	24	specific	specific	ADJ
cusj-10967	179	25	tumor	tumor	NOUN
cusj-10967	179	26	targeting	target	VERB
cusj-10967	179	27	and	and	CCONJ
cusj-10967	179	28	antitumor	antitumor	PROPN
cusj-10967	179	29	effectiveness	effectiveness	NOUN
cusj-10967	179	30	.	.	PUNCT
cusj-10967	180	1	other	other	ADJ
cusj-10967	180	2	types	type	NOUN
cusj-10967	180	3	of	of	ADP
cusj-10967	180	4	cancer	cancer	NOUN
cusj-10967	180	5	,	,	PUNCT
cusj-10967	180	6	such	such	ADJ
cusj-10967	180	7	as	as	ADP
cusj-10967	180	8	pancreatic	pancreatic	ADJ
cusj-10967	180	9	ductal	ductal	ADJ
cusj-10967	180	10	adenocarcinoma	adenocarcinoma	NOUN
cusj-10967	180	11	(	(	PUNCT
cusj-10967	180	12	pdac	pdac	NOUN
cusj-10967	180	13	)	)	PUNCT
cusj-10967	180	14	,	,	PUNCT
cusj-10967	180	15	have	have	AUX
cusj-10967	180	16	also	also	ADV
cusj-10967	180	17	demonstrated	demonstrate	VERB
cusj-10967	180	18	resistance	resistance	NOUN
cusj-10967	180	19	to	to	ADP
cusj-10967	180	20	treatment	treatment	NOUN
cusj-10967	180	21	.	.	PUNCT
cusj-10967	181	1	seegers	seeger	NOUN
cusj-10967	181	2	and	and	CCONJ
cusj-10967	181	3	colleagues	colleague	NOUN
cusj-10967	181	4	engineered	engineer	VERB
cusj-10967	181	5	an	an	DET
cusj-10967	181	6	oncolytic	oncolytic	ADJ
cusj-10967	181	7	vesicular	vesicular	ADJ
cusj-10967	181	8	stomatitis	stomatitis	NOUN
cusj-10967	181	9	virus	virus	NOUN
cusj-10967	181	10	that	that	PRON
cusj-10967	181	11	effectively	effectively	ADV
cusj-10967	181	12	infects	infect	VERB
cusj-10967	181	13	treatment	treatment	NOUN
cusj-10967	181	14	-	-	PUNCT
cusj-10967	181	15	resistant	resistant	ADJ
cusj-10967	181	16	pdac	pdac	NOUN
cusj-10967	181	17	cells	cell	NOUN
cusj-10967	181	18	due	due	ADJ
cusj-10967	181	19	to	to	ADP
cusj-10967	181	20	enhanced	enhance	VERB
cusj-10967	181	21	viral	viral	ADJ
cusj-10967	181	22	attachment	attachment	NOUN
cusj-10967	181	23	.	.	PUNCT
cusj-10967	182	1	the	the	DET
cusj-10967	182	2	researchers	researcher	NOUN
cusj-10967	182	3	used	use	VERB
cusj-10967	182	4	directed	direct	VERB
cusj-10967	182	5	viral	viral	ADJ
cusj-10967	182	6	evolution	evolution	NOUN
cusj-10967	182	7	to	to	PART
cusj-10967	182	8	create	create	VERB
cusj-10967	182	9	mutations	mutation	NOUN
cusj-10967	182	10	in	in	ADP
cusj-10967	182	11	the	the	DET
cusj-10967	182	12	viral	viral	ADJ
cusj-10967	182	13	genes	gene	NOUN
cusj-10967	182	14	and	and	CCONJ
cusj-10967	182	15	identified	identify	VERB
cusj-10967	182	16	two	two	NUM
cusj-10967	182	17	mutations	mutation	NOUN
cusj-10967	182	18	that	that	PRON
cusj-10967	182	19	appeared	appear	VERB
cusj-10967	182	20	in	in	ADP
cusj-10967	182	21	more	more	ADJ
cusj-10967	182	22	than	than	ADP
cusj-10967	182	23	one	one	NUM
cusj-10967	182	24	evolved	evolved	ADJ
cusj-10967	182	25	virus	virus	NOUN
cusj-10967	182	26	.	.	PUNCT
cusj-10967	183	1	ovs	ovs	NOUN
cusj-10967	184	1	with	with	ADP
cusj-10967	184	2	these	these	DET
cusj-10967	184	3	mutations	mutation	NOUN
cusj-10967	184	4	were	be	AUX
cusj-10967	184	5	advanced	advanced	ADJ
cusj-10967	184	6	to	to	ADP
cusj-10967	184	7	testing	testing	NOUN
cusj-10967	184	8	and	and	CCONJ
cusj-10967	184	9	demonstrated	demonstrate	VERB
cusj-10967	184	10	increased	increase	VERB
cusj-10967	184	11	replication	replication	NOUN
cusj-10967	184	12	in	in	ADP
cusj-10967	184	13	treatment	treatment	NOUN
cusj-10967	184	14	-	-	PUNCT
cusj-10967	184	15	resistant	resistant	ADJ
cusj-10967	184	16	pdac	pdac	NOUN
cusj-10967	184	17	cells.39	cells.39	NOUN
cusj-10967	184	18	this	this	DET
cusj-10967	184	19	finding	finding	NOUN
cusj-10967	184	20	indicates	indicate	VERB
cusj-10967	184	21	that	that	SCONJ
cusj-10967	184	22	directed	direct	VERB
cusj-10967	184	23	evolution	evolution	NOUN
cusj-10967	184	24	could	could	AUX
cusj-10967	184	25	be	be	AUX
cusj-10967	184	26	used	use	VERB
cusj-10967	184	27	to	to	PART
cusj-10967	184	28	identify	identify	VERB
cusj-10967	184	29	other	other	ADJ
cusj-10967	184	30	beneficial	beneficial	ADJ
cusj-10967	184	31	mutations	mutation	NOUN
cusj-10967	184	32	in	in	ADP
cusj-10967	184	33	ovs	ovs	NOUN
cusj-10967	184	34	.	.	PUNCT
cusj-10967	185	1	additionally	additionally	ADV
cusj-10967	185	2	,	,	PUNCT
cusj-10967	185	3	other	other	ADJ
cusj-10967	185	4	treatment	treatment	NOUN
cusj-10967	185	5	-	-	PUNCT
cusj-10967	185	6	resistant	resistant	ADJ
cusj-10967	185	7	cancers	cancer	NOUN
cusj-10967	185	8	could	could	AUX
cusj-10967	185	9	potentially	potentially	ADV
cusj-10967	185	10	be	be	AUX
cusj-10967	185	11	treated	treat	VERB
cusj-10967	185	12	more	more	ADV
cusj-10967	185	13	effectively	effectively	ADV
cusj-10967	185	14	by	by	ADP
cusj-10967	185	15	ovs	ovs	NOUN
cusj-10967	185	16	which	which	PRON
cusj-10967	185	17	are	be	AUX
cusj-10967	185	18	designed	design	VERB
cusj-10967	185	19	to	to	PART
cusj-10967	185	20	utilize	utilize	VERB
cusj-10967	185	21	targeting	target	VERB
cusj-10967	185	22	mechanisms	mechanism	NOUN
cusj-10967	185	23	that	that	PRON
cusj-10967	185	24	are	be	AUX
cusj-10967	185	25	not	not	PART
cusj-10967	185	26	involved	involve	VERB
cusj-10967	185	27	with	with	ADP
cusj-10967	185	28	the	the	DET
cusj-10967	185	29	cancer	cancer	NOUN
cusj-10967	185	30	’s	’s	PART
cusj-10967	185	31	resistance	resistance	NOUN
cusj-10967	185	32	to	to	ADP
cusj-10967	185	33	treatment	treatment	NOUN
cusj-10967	185	34	.	.	PUNCT
cusj-10967	186	1	an	an	DET
cusj-10967	186	2	ov	ov	INTJ
cusj-10967	186	3	that	that	PRON
cusj-10967	186	4	relies	rely	VERB
cusj-10967	186	5	on	on	ADP
cusj-10967	186	6	a	a	DET
cusj-10967	186	7	different	different	ADJ
cusj-10967	186	8	targeting	targeting	NOUN
cusj-10967	186	9	mechanism	mechanism	NOUN
cusj-10967	186	10	could	could	AUX
cusj-10967	186	11	identify	identify	VERB
cusj-10967	186	12	and	and	CCONJ
cusj-10967	186	13	infect	infect	VERB
cusj-10967	186	14	cancer	cancer	NOUN
cusj-10967	186	15	cells	cell	NOUN
cusj-10967	186	16	more	more	ADV
cusj-10967	186	17	effectively	effectively	ADV
cusj-10967	186	18	than	than	ADP
cusj-10967	186	19	an	an	DET
cusj-10967	186	20	ov	ov	NOUN
cusj-10967	186	21	that	that	PRON
cusj-10967	186	22	relies	rely	VERB
cusj-10967	186	23	on	on	ADP
cusj-10967	186	24	a	a	DET
cusj-10967	186	25	mechanism	mechanism	NOUN
cusj-10967	186	26	which	which	PRON
cusj-10967	186	27	is	be	AUX
cusj-10967	186	28	made	make	VERB
cusj-10967	186	29	ineffective	ineffective	ADJ
cusj-10967	186	30	by	by	ADP
cusj-10967	186	31	a	a	DET
cusj-10967	186	32	mutation	mutation	NOUN
cusj-10967	186	33	in	in	ADP
cusj-10967	186	34	the	the	DET
cusj-10967	186	35	cancer	cancer	NOUN
cusj-10967	186	36	cells	cell	NOUN
cusj-10967	186	37	.	.	PUNCT
cusj-10967	187	1	significant	significant	ADJ
cusj-10967	187	2	improvements	improvement	NOUN
cusj-10967	187	3	have	have	AUX
cusj-10967	187	4	been	be	AUX
cusj-10967	187	5	made	make	VERB
cusj-10967	187	6	in	in	ADP
cusj-10967	187	7	tumor	tumor	NOUN
cusj-10967	187	8	targeting	target	VERB
cusj-10967	187	9	specificity	specificity	NOUN
cusj-10967	187	10	by	by	ADP
cusj-10967	187	11	ovs	ovs	NOUN
cusj-10967	187	12	and	and	CCONJ
cusj-10967	187	13	immune	immune	ADJ
cusj-10967	187	14	cells	cell	NOUN
cusj-10967	187	15	.	.	PUNCT
cusj-10967	188	1	this	this	DET
cusj-10967	188	2	approach	approach	NOUN
cusj-10967	188	3	includes	include	VERB
cusj-10967	188	4	a	a	DET
cusj-10967	188	5	number	number	NOUN
cusj-10967	188	6	of	of	ADP
cusj-10967	188	7	different	different	ADJ
cusj-10967	188	8	specific	specific	ADJ
cusj-10967	188	9	mechanisms	mechanism	NOUN
cusj-10967	188	10	that	that	PRON
cusj-10967	188	11	have	have	AUX
cusj-10967	188	12	been	be	AUX
cusj-10967	188	13	utilized	utilize	VERB
cusj-10967	188	14	to	to	PART
cusj-10967	188	15	improve	improve	VERB
cusj-10967	188	16	oncolytic	oncolytic	ADJ
cusj-10967	188	17	virotherapy	virotherapy	NOUN
cusj-10967	188	18	.	.	PUNCT
cusj-10967	189	1	ovs	ovs	PROPN
cusj-10967	189	2	can	can	AUX
cusj-10967	189	3	infect	infect	VERB
cusj-10967	189	4	cancer	cancer	NOUN
cusj-10967	189	5	cells	cell	NOUN
cusj-10967	189	6	and	and	CCONJ
cusj-10967	189	7	cause	cause	VERB
cusj-10967	189	8	the	the	DET
cusj-10967	189	9	expression	expression	NOUN
cusj-10967	189	10	of	of	ADP
cusj-10967	189	11	different	different	ADJ
cusj-10967	189	12	signaling	signal	VERB
cusj-10967	189	13	molecules	molecule	NOUN
cusj-10967	189	14	and	and	CCONJ
cusj-10967	189	15	other	other	ADJ
cusj-10967	189	16	proteins	protein	NOUN
cusj-10967	189	17	on	on	ADP
cusj-10967	189	18	their	their	PRON
cusj-10967	189	19	surfaces	surface	NOUN
cusj-10967	189	20	that	that	PRON
cusj-10967	189	21	aid	aid	VERB
cusj-10967	189	22	immune	immune	ADJ
cusj-10967	189	23	cells	cell	NOUN
cusj-10967	189	24	in	in	ADP
cusj-10967	189	25	identifying	identify	VERB
cusj-10967	189	26	them	they	PRON
cusj-10967	189	27	.	.	PUNCT
cusj-10967	190	1	ovs	ovs	PROPN
cusj-10967	190	2	can	can	AUX
cusj-10967	190	3	also	also	ADV
cusj-10967	190	4	be	be	AUX
cusj-10967	190	5	engineered	engineer	VERB
cusj-10967	190	6	to	to	PART
cusj-10967	190	7	improve	improve	VERB
cusj-10967	190	8	their	their	PRON
cusj-10967	190	9	infection	infection	NOUN
cusj-10967	190	10	specificity	specificity	NOUN
cusj-10967	190	11	and	and	CCONJ
cusj-10967	190	12	more	more	ADV
cusj-10967	190	13	selectively	selectively	ADV
cusj-10967	190	14	infect	infect	VERB
cusj-10967	190	15	cancer	cancer	NOUN
cusj-10967	190	16	cells	cell	NOUN
cusj-10967	190	17	.	.	PUNCT
cusj-10967	191	1	engineering	engineering	NOUN
cusj-10967	191	2	of	of	ADP
cusj-10967	191	3	ovs	ovs	NOUN
cusj-10967	191	4	can	can	AUX
cusj-10967	191	5	also	also	ADV
cusj-10967	191	6	be	be	AUX
cusj-10967	191	7	specialized	specialize	VERB
cusj-10967	191	8	to	to	ADP
cusj-10967	191	9	different	different	ADJ
cusj-10967	191	10	cancer	cancer	NOUN
cusj-10967	191	11	types	type	NOUN
cusj-10967	191	12	in	in	ADP
cusj-10967	191	13	order	order	NOUN
cusj-10967	191	14	to	to	PART
cusj-10967	191	15	take	take	VERB
cusj-10967	191	16	advantage	advantage	NOUN
cusj-10967	191	17	of	of	ADP
cusj-10967	191	18	columbia	columbia	PROPN
cusj-10967	191	19	undergraduate	undergraduate	PROPN
cusj-10967	191	20	science	science	PROPN
cusj-10967	191	21	journal	journal	PROPN
cusj-10967	191	22	vol	vol	NOUN
cusj-10967	191	23	.	.	PROPN
cusj-10967	191	24	18	18	NUM
cusj-10967	191	25	,	,	PUNCT
cusj-10967	191	26	2024	2024	NUM
cusj-10967	191	27	manjila	manjila	NOUN
cusj-10967	191	28	certain	certain	ADJ
cusj-10967	191	29	receptor	receptor	NOUN
cusj-10967	191	30	-	-	PUNCT
cusj-10967	191	31	ligand	ligand	NOUN
cusj-10967	191	32	interactions	interaction	NOUN
cusj-10967	191	33	that	that	PRON
cusj-10967	191	34	may	may	AUX
cusj-10967	191	35	be	be	AUX
cusj-10967	191	36	upregulated	upregulate	VERB
cusj-10967	191	37	in	in	ADP
cusj-10967	191	38	different	different	ADJ
cusj-10967	191	39	cancers	cancer	NOUN
cusj-10967	191	40	.	.	PUNCT
cusj-10967	192	1	this	this	PRON
cusj-10967	192	2	could	could	AUX
cusj-10967	192	3	lead	lead	VERB
cusj-10967	192	4	to	to	ADP
cusj-10967	192	5	the	the	DET
cusj-10967	192	6	development	development	NOUN
cusj-10967	192	7	of	of	ADP
cusj-10967	192	8	an	an	DET
cusj-10967	192	9	ov	ov	PROPN
cusj-10967	192	10	repertoire	repertoire	NOUN
cusj-10967	192	11	that	that	PRON
cusj-10967	192	12	demonstrates	demonstrate	VERB
cusj-10967	192	13	a	a	DET
cusj-10967	192	14	significant	significant	ADJ
cusj-10967	192	15	degree	degree	NOUN
cusj-10967	192	16	of	of	ADP
cusj-10967	192	17	precision	precision	NOUN
cusj-10967	192	18	in	in	ADP
cusj-10967	192	19	its	its	PRON
cusj-10967	192	20	mechanism	mechanism	NOUN
cusj-10967	192	21	and	and	CCONJ
cusj-10967	192	22	cytotoxicity	cytotoxicity	NOUN
cusj-10967	192	23	.	.	PUNCT
cusj-10967	193	1	oncolytic	oncolytic	ADJ
cusj-10967	193	2	viruses	virus	NOUN
cusj-10967	193	3	and	and	CCONJ
cusj-10967	193	4	car	car	NOUN
cusj-10967	193	5	-	-	PUNCT
cusj-10967	193	6	t	t	NOUN
cusj-10967	193	7	cell	cell	NOUN
cusj-10967	193	8	therapy	therapy	NOUN
cusj-10967	193	9	certain	certain	ADJ
cusj-10967	193	10	types	type	NOUN
cusj-10967	193	11	of	of	ADP
cusj-10967	193	12	cancer	cancer	NOUN
cusj-10967	193	13	,	,	PUNCT
cusj-10967	193	14	particularly	particularly	ADV
cusj-10967	193	15	blood	blood	NOUN
cusj-10967	193	16	cancers	cancer	NOUN
cusj-10967	193	17	,	,	PUNCT
cusj-10967	193	18	can	can	AUX
cusj-10967	193	19	be	be	AUX
cusj-10967	193	20	treated	treat	VERB
cusj-10967	193	21	using	use	VERB
cusj-10967	193	22	chimeric	chimeric	ADJ
cusj-10967	193	23	antigen	antigen	ADJ
cusj-10967	193	24	receptor	receptor	NOUN
cusj-10967	193	25	t	t	NOUN
cusj-10967	193	26	(	(	PUNCT
cusj-10967	193	27	car	car	NOUN
cusj-10967	193	28	-	-	PUNCT
cusj-10967	193	29	t	t	PROPN
cusj-10967	193	30	)	)	PUNCT
cusj-10967	193	31	cell	cell	NOUN
cusj-10967	193	32	therapy	therapy	NOUN
cusj-10967	193	33	.	.	PUNCT
cusj-10967	194	1	this	this	DET
cusj-10967	194	2	treatment	treatment	NOUN
cusj-10967	194	3	utilizes	utilize	VERB
cusj-10967	194	4	immune	immune	ADJ
cusj-10967	194	5	cells	cell	NOUN
cusj-10967	194	6	taken	take	VERB
cusj-10967	194	7	from	from	ADP
cusj-10967	194	8	the	the	DET
cusj-10967	194	9	patient	patient	NOUN
cusj-10967	194	10	and	and	CCONJ
cusj-10967	194	11	engineered	engineer	VERB
cusj-10967	194	12	to	to	PART
cusj-10967	194	13	carry	carry	VERB
cusj-10967	194	14	receptors	receptor	NOUN
cusj-10967	194	15	that	that	PRON
cusj-10967	194	16	better	well	ADV
cusj-10967	194	17	allow	allow	VERB
cusj-10967	194	18	them	they	PRON
cusj-10967	194	19	to	to	PART
cusj-10967	194	20	target	target	VERB
cusj-10967	194	21	cancer	cancer	NOUN
cusj-10967	194	22	cells	cell	NOUN
cusj-10967	194	23	.	.	PUNCT
cusj-10967	195	1	this	this	DET
cusj-10967	195	2	method	method	NOUN
cusj-10967	195	3	is	be	AUX
cusj-10967	195	4	beneficial	beneficial	ADJ
cusj-10967	195	5	because	because	SCONJ
cusj-10967	195	6	it	it	PRON
cusj-10967	195	7	relies	rely	VERB
cusj-10967	195	8	on	on	ADP
cusj-10967	195	9	the	the	DET
cusj-10967	195	10	patient	patient	NOUN
cusj-10967	195	11	’s	’s	PART
cusj-10967	195	12	own	own	ADJ
cusj-10967	195	13	cells	cell	NOUN
cusj-10967	195	14	and	and	CCONJ
cusj-10967	195	15	reduces	reduce	VERB
cusj-10967	195	16	the	the	DET
cusj-10967	195	17	likelihood	likelihood	NOUN
cusj-10967	195	18	of	of	ADP
cusj-10967	195	19	severe	severe	ADJ
cusj-10967	195	20	side	side	NOUN
cusj-10967	195	21	effects	effect	NOUN
cusj-10967	195	22	.	.	PUNCT
cusj-10967	196	1	the	the	DET
cusj-10967	196	2	immunosuppressive	immunosuppressive	ADJ
cusj-10967	196	3	nature	nature	NOUN
cusj-10967	196	4	of	of	ADP
cusj-10967	196	5	the	the	DET
cusj-10967	196	6	tumor	tumor	NOUN
cusj-10967	196	7	microenvironment	microenvironment	NOUN
cusj-10967	196	8	decreases	decrease	VERB
cusj-10967	196	9	the	the	DET
cusj-10967	196	10	efficiency	efficiency	NOUN
cusj-10967	196	11	of	of	ADP
cusj-10967	196	12	immune	immune	ADJ
cusj-10967	196	13	cell	cell	NOUN
cusj-10967	196	14	-	-	PUNCT
cusj-10967	196	15	based	base	VERB
cusj-10967	196	16	therapies	therapy	NOUN
cusj-10967	196	17	in	in	ADP
cusj-10967	196	18	the	the	DET
cusj-10967	196	19	same	same	ADJ
cusj-10967	196	20	manner	manner	NOUN
cusj-10967	196	21	as	as	SCONJ
cusj-10967	196	22	it	it	PRON
cusj-10967	196	23	decreases	decrease	VERB
cusj-10967	196	24	the	the	DET
cusj-10967	196	25	efficiency	efficiency	NOUN
cusj-10967	196	26	of	of	ADP
cusj-10967	196	27	natural	natural	ADJ
cusj-10967	196	28	immune	immune	ADJ
cusj-10967	196	29	responses	response	NOUN
cusj-10967	196	30	.	.	PUNCT
cusj-10967	197	1	this	this	PRON
cusj-10967	197	2	means	mean	VERB
cusj-10967	197	3	that	that	SCONJ
cusj-10967	197	4	car	car	NOUN
cusj-10967	197	5	-	-	PUNCT
cusj-10967	197	6	t	t	NOUN
cusj-10967	197	7	cell	cell	NOUN
cusj-10967	197	8	therapy	therapy	NOUN
cusj-10967	197	9	could	could	AUX
cusj-10967	197	10	potentially	potentially	ADV
cusj-10967	197	11	be	be	AUX
cusj-10967	197	12	ineffective	ineffective	ADJ
cusj-10967	197	13	against	against	ADP
cusj-10967	197	14	tumor	tumor	NOUN
cusj-10967	197	15	growths	growth	NOUN
cusj-10967	197	16	that	that	PRON
cusj-10967	197	17	express	express	VERB
cusj-10967	197	18	high	high	ADJ
cusj-10967	197	19	levels	level	NOUN
cusj-10967	197	20	of	of	ADP
cusj-10967	197	21	immunosuppression.40	immunosuppression.40	PROPN
cusj-10967	197	22	combining	combine	VERB
cusj-10967	197	23	car	car	NOUN
cusj-10967	197	24	-	-	PUNCT
cusj-10967	197	25	t	t	NOUN
cusj-10967	197	26	cell	cell	NOUN
cusj-10967	197	27	therapy	therapy	NOUN
cusj-10967	197	28	with	with	ADP
cusj-10967	197	29	another	another	DET
cusj-10967	197	30	form	form	NOUN
cusj-10967	197	31	of	of	ADP
cusj-10967	197	32	treatment	treatment	NOUN
cusj-10967	197	33	could	could	AUX
cusj-10967	197	34	potentially	potentially	ADV
cusj-10967	197	35	overcome	overcome	VERB
cusj-10967	197	36	the	the	DET
cusj-10967	197	37	challenge	challenge	NOUN
cusj-10967	197	38	of	of	ADP
cusj-10967	197	39	immunosuppression	immunosuppression	NOUN
cusj-10967	197	40	and	and	CCONJ
cusj-10967	197	41	improve	improve	VERB
cusj-10967	197	42	the	the	DET
cusj-10967	197	43	antitumor	antitumor	PROPN
cusj-10967	197	44	effectiveness	effectiveness	NOUN
cusj-10967	197	45	of	of	ADP
cusj-10967	197	46	the	the	DET
cusj-10967	197	47	therapeutic	therapeutic	ADJ
cusj-10967	197	48	approach	approach	NOUN
cusj-10967	197	49	.	.	PUNCT
cusj-10967	198	1	oncolytic	oncolytic	ADJ
cusj-10967	198	2	virotherapy	virotherapy	PROPN
cusj-10967	198	3	can	can	AUX
cusj-10967	198	4	be	be	AUX
cusj-10967	198	5	utilized	utilize	VERB
cusj-10967	198	6	to	to	PART
cusj-10967	198	7	counteract	counteract	VERB
cusj-10967	198	8	immunosuppression	immunosuppression	NOUN
cusj-10967	198	9	in	in	ADP
cusj-10967	198	10	the	the	DET
cusj-10967	198	11	tumor	tumor	NOUN
cusj-10967	198	12	microenvironment	microenvironment	NOUN
cusj-10967	198	13	.	.	PUNCT
cusj-10967	199	1	after	after	SCONJ
cusj-10967	199	2	ovs	ovs	NOUN
cusj-10967	199	3	have	have	AUX
cusj-10967	199	4	been	be	AUX
cusj-10967	199	5	implemented	implement	VERB
cusj-10967	199	6	to	to	PART
cusj-10967	199	7	cause	cause	VERB
cusj-10967	199	8	the	the	DET
cusj-10967	199	9	tumor	tumor	NOUN
cusj-10967	199	10	region	region	NOUN
cusj-10967	199	11	to	to	PART
cusj-10967	199	12	become	become	VERB
cusj-10967	199	13	immunologically	immunologically	ADV
cusj-10967	199	14	active	active	ADJ
cusj-10967	199	15	,	,	PUNCT
cusj-10967	199	16	car	car	NOUN
cusj-10967	199	17	-	-	PUNCT
cusj-10967	199	18	t	t	NOUN
cusj-10967	199	19	cells	cell	NOUN
cusj-10967	199	20	can	can	AUX
cusj-10967	199	21	more	more	ADV
cusj-10967	199	22	easily	easily	ADV
cusj-10967	199	23	infiltrate	infiltrate	VERB
cusj-10967	199	24	the	the	DET
cusj-10967	199	25	tumor	tumor	NOUN
cusj-10967	199	26	and	and	CCONJ
cusj-10967	199	27	cause	cause	VERB
cusj-10967	199	28	cancer	cancer	NOUN
cusj-10967	199	29	cell	cell	NOUN
cusj-10967	199	30	death	death	NOUN
cusj-10967	199	31	.	.	PUNCT
cusj-10967	200	1	mckenna	mckenna	PROPN
cusj-10967	200	2	and	and	CCONJ
cusj-10967	200	3	colleagues	colleague	NOUN
cusj-10967	200	4	developed	develop	VERB
cusj-10967	200	5	a	a	DET
cusj-10967	200	6	multi	multi	ADJ
cusj-10967	200	7	-	-	ADJ
cusj-10967	200	8	component	component	ADJ
cusj-10967	200	9	oncolytic	oncolytic	NOUN
cusj-10967	200	10	therapeutic	therapeutic	NOUN
cusj-10967	200	11	delivered	deliver	VERB
cusj-10967	200	12	by	by	ADP
cusj-10967	200	13	mesenchymal	mesenchymal	ADJ
cusj-10967	200	14	stromal	stromal	ADJ
cusj-10967	200	15	cells	cell	NOUN
cusj-10967	200	16	combined	combine	VERB
cusj-10967	200	17	with	with	ADP
cusj-10967	200	18	car	car	NOUN
cusj-10967	200	19	-	-	PUNCT
cusj-10967	200	20	t	t	NOUN
cusj-10967	200	21	cell	cell	NOUN
cusj-10967	200	22	therapy	therapy	NOUN
cusj-10967	200	23	to	to	PART
cusj-10967	200	24	achieve	achieve	VERB
cusj-10967	200	25	a	a	DET
cusj-10967	200	26	greater	great	ADJ
cusj-10967	200	27	antitumor	antitumor	NOUN
cusj-10967	200	28	effect	effect	NOUN
cusj-10967	200	29	.	.	PUNCT
cusj-10967	201	1	the	the	DET
cusj-10967	201	2	first	first	ADJ
cusj-10967	201	3	stage	stage	NOUN
cusj-10967	201	4	of	of	ADP
cusj-10967	201	5	this	this	DET
cusj-10967	201	6	therapeutic	therapeutic	ADJ
cusj-10967	201	7	strategy	strategy	NOUN
cusj-10967	201	8	is	be	AUX
cusj-10967	201	9	the	the	DET
cusj-10967	201	10	delivery	delivery	NOUN
cusj-10967	201	11	of	of	ADP
cusj-10967	201	12	oncolytic	oncolytic	ADJ
cusj-10967	201	13	viruses	virus	NOUN
cusj-10967	201	14	by	by	ADP
cusj-10967	201	15	the	the	DET
cusj-10967	201	16	mesenchymal	mesenchymal	ADJ
cusj-10967	201	17	stromal	stromal	ADJ
cusj-10967	201	18	cells	cell	NOUN
cusj-10967	201	19	.	.	PUNCT
cusj-10967	202	1	after	after	SCONJ
cusj-10967	202	2	the	the	DET
cusj-10967	202	3	viruses	virus	NOUN
cusj-10967	202	4	have	have	AUX
cusj-10967	202	5	been	be	AUX
cusj-10967	202	6	delivered	deliver	VERB
cusj-10967	202	7	,	,	PUNCT
cusj-10967	202	8	they	they	PRON
cusj-10967	202	9	infect	infect	VERB
cusj-10967	202	10	the	the	DET
cusj-10967	202	11	tumor	tumor	NOUN
cusj-10967	202	12	and	and	CCONJ
cusj-10967	202	13	reduce	reduce	VERB
cusj-10967	202	14	immunosuppression	immunosuppression	NOUN
cusj-10967	202	15	in	in	ADP
cusj-10967	202	16	the	the	DET
cusj-10967	202	17	microenvironment	microenvironment	NOUN
cusj-10967	202	18	.	.	PUNCT
cusj-10967	203	1	the	the	DET
cusj-10967	203	2	final	final	ADJ
cusj-10967	203	3	stage	stage	NOUN
cusj-10967	203	4	involves	involve	VERB
cusj-10967	203	5	infiltration	infiltration	NOUN
cusj-10967	203	6	of	of	ADP
cusj-10967	203	7	the	the	DET
cusj-10967	203	8	tumor	tumor	NOUN
cusj-10967	203	9	by	by	ADP
cusj-10967	203	10	car	car	NOUN
cusj-10967	203	11	-	-	PUNCT
cusj-10967	203	12	t	t	NOUN
cusj-10967	203	13	cells	cell	NOUN
cusj-10967	203	14	and	and	CCONJ
cusj-10967	203	15	the	the	DET
cusj-10967	203	16	death	death	NOUN
cusj-10967	203	17	of	of	ADP
cusj-10967	203	18	cancer	cancer	NOUN
cusj-10967	203	19	cells	cell	NOUN
cusj-10967	203	20	.	.	PUNCT
cusj-10967	204	1	this	this	DET
cusj-10967	204	2	combined	combine	VERB
cusj-10967	204	3	treatment	treatment	NOUN
cusj-10967	204	4	was	be	AUX
cusj-10967	204	5	more	more	ADV
cusj-10967	204	6	effective	effective	ADJ
cusj-10967	204	7	than	than	ADP
cusj-10967	204	8	the	the	DET
cusj-10967	204	9	engineered	engineer	VERB
cusj-10967	204	10	ovs	ovs	NOUN
cusj-10967	204	11	alone.41	alone.41	NOUN
cusj-10967	204	12	the	the	DET
cusj-10967	204	13	researchers	researcher	NOUN
cusj-10967	204	14	also	also	ADV
cusj-10967	204	15	found	find	VERB
cusj-10967	204	16	that	that	SCONJ
cusj-10967	204	17	t	t	PROPN
cusj-10967	204	18	cells	cell	NOUN
cusj-10967	204	19	were	be	AUX
cusj-10967	204	20	identified	identify	VERB
cusj-10967	204	21	in	in	ADP
cusj-10967	204	22	larger	large	ADJ
cusj-10967	204	23	numbers	number	NOUN
cusj-10967	204	24	within	within	ADP
cusj-10967	204	25	the	the	DET
cusj-10967	204	26	tumor	tumor	NOUN
cusj-10967	204	27	mass	mass	PROPN
cusj-10967	204	28	.	.	PUNCT
cusj-10967	205	1	this	this	DET
cusj-10967	205	2	result	result	NOUN
cusj-10967	205	3	indicates	indicate	VERB
cusj-10967	205	4	that	that	SCONJ
cusj-10967	205	5	the	the	DET
cusj-10967	205	6	immune	immune	ADJ
cusj-10967	205	7	response	response	NOUN
cusj-10967	205	8	is	be	AUX
cusj-10967	205	9	amplified	amplify	VERB
cusj-10967	205	10	in	in	ADP
cusj-10967	205	11	addition	addition	NOUN
cusj-10967	205	12	to	to	ADP
cusj-10967	205	13	the	the	DET
cusj-10967	205	14	car	car	NOUN
cusj-10967	205	15	-	-	PUNCT
cusj-10967	205	16	t	t	NOUN
cusj-10967	205	17	cell	cell	NOUN
cusj-10967	205	18	activity	activity	NOUN
cusj-10967	205	19	.	.	PUNCT
cusj-10967	206	1	the	the	DET
cusj-10967	206	2	concept	concept	NOUN
cusj-10967	206	3	of	of	ADP
cusj-10967	206	4	utilizing	utilize	VERB
cusj-10967	206	5	chimeric	chimeric	ADJ
cusj-10967	206	6	receptors	receptor	NOUN
cusj-10967	206	7	and	and	CCONJ
cusj-10967	206	8	combination	combination	NOUN
cusj-10967	206	9	therapy	therapy	NOUN
cusj-10967	206	10	for	for	ADP
cusj-10967	206	11	anti	anti	ADJ
cusj-10967	206	12	-	-	ADJ
cusj-10967	206	13	cancer	cancer	ADJ
cusj-10967	206	14	activity	activity	NOUN
cusj-10967	206	15	has	have	AUX
cusj-10967	206	16	been	be	AUX
cusj-10967	206	17	investigated	investigate	VERB
cusj-10967	206	18	by	by	ADP
cusj-10967	206	19	researchers	researcher	NOUN
cusj-10967	206	20	developing	develop	VERB
cusj-10967	206	21	ovs	ovs	NOUN
cusj-10967	206	22	as	as	ADV
cusj-10967	206	23	well	well	ADV
cusj-10967	206	24	.	.	PUNCT
cusj-10967	207	1	froechlich	froechlich	PROPN
cusj-10967	207	2	and	and	CCONJ
cusj-10967	207	3	colleagues	colleague	NOUN
cusj-10967	207	4	engineered	engineer	VERB
cusj-10967	207	5	an	an	DET
cusj-10967	207	6	ov	ov	NOUN
cusj-10967	207	7	targeted	target	VERB
cusj-10967	207	8	to	to	ADP
cusj-10967	207	9	mesothelin	mesothelin	NOUN
cusj-10967	207	10	,	,	PUNCT
cusj-10967	207	11	a	a	DET
cusj-10967	207	12	molecule	molecule	NOUN
cusj-10967	207	13	expressed	express	VERB
cusj-10967	207	14	by	by	ADP
cusj-10967	207	15	cancer	cancer	NOUN
cusj-10967	207	16	cells.42	cells.42	NOUN
cusj-10967	207	17	they	they	PRON
cusj-10967	207	18	achieved	achieve	VERB
cusj-10967	207	19	this	this	PRON
cusj-10967	207	20	by	by	ADP
cusj-10967	207	21	creating	create	VERB
cusj-10967	207	22	a	a	DET
cusj-10967	207	23	chimeric	chimeric	ADJ
cusj-10967	207	24	receptor	receptor	NOUN
cusj-10967	207	25	that	that	PRON
cusj-10967	207	26	included	include	VERB
cusj-10967	207	27	an	an	DET
cusj-10967	207	28	immune	immune	ADJ
cusj-10967	207	29	component	component	NOUN
cusj-10967	207	30	and	and	CCONJ
cusj-10967	207	31	the	the	DET
cusj-10967	207	32	binding	bind	VERB
cusj-10967	207	33	site	site	NOUN
cusj-10967	207	34	for	for	ADP
cusj-10967	207	35	the	the	DET
cusj-10967	207	36	cancer	cancer	NOUN
cusj-10967	207	37	ligand	ligand	NOUN
cusj-10967	207	38	target	target	NOUN
cusj-10967	207	39	.	.	PUNCT
cusj-10967	208	1	huang	huang	PROPN
cusj-10967	208	2	and	and	CCONJ
cusj-10967	208	3	colleagues	colleague	NOUN
cusj-10967	208	4	developed	develop	VERB
cusj-10967	208	5	an	an	DET
cusj-10967	208	6	oncolytic	oncolytic	ADJ
cusj-10967	208	7	adenovirus	adenovirus	NOUN
cusj-10967	208	8	that	that	PRON
cusj-10967	208	9	contains	contain	VERB
cusj-10967	208	10	a	a	DET
cusj-10967	208	11	gene	gene	NOUN
cusj-10967	208	12	circuit	circuit	NOUN
cusj-10967	208	13	for	for	ADP
cusj-10967	208	14	the	the	DET
cusj-10967	208	15	control	control	NOUN
cusj-10967	208	16	of	of	ADP
cusj-10967	208	17	viral	viral	ADJ
cusj-10967	208	18	replication	replication	NOUN
cusj-10967	208	19	after	after	ADP
cusj-10967	208	20	infecting	infect	VERB
cusj-10967	208	21	cancer	cancer	NOUN
cusj-10967	208	22	cells.43	cells.43	PROPN
cusj-10967	208	23	simulation	simulation	NOUN
cusj-10967	208	24	of	of	ADP
cusj-10967	208	25	the	the	DET
cusj-10967	208	26	population	population	NOUN
cusj-10967	208	27	dynamics	dynamic	NOUN
cusj-10967	208	28	of	of	ADP
cusj-10967	208	29	the	the	DET
cusj-10967	208	30	ov	ov	PROPN
cusj-10967	208	31	revealed	reveal	VERB
cusj-10967	208	32	that	that	SCONJ
cusj-10967	208	33	controlling	control	VERB
cusj-10967	208	34	immune	immune	NOUN
cusj-10967	208	35	signaling	signal	VERB
cusj-10967	208	36	at	at	ADP
cusj-10967	208	37	the	the	DET
cusj-10967	208	38	tumor	tumor	NOUN
cusj-10967	208	39	site	site	NOUN
cusj-10967	208	40	would	would	AUX
cusj-10967	208	41	be	be	AUX
cusj-10967	208	42	more	more	ADV
cusj-10967	208	43	effective	effective	ADJ
cusj-10967	208	44	than	than	ADP
cusj-10967	208	45	combination	combination	NOUN
cusj-10967	208	46	therapy	therapy	NOUN
cusj-10967	208	47	using	use	VERB
cusj-10967	208	48	an	an	DET
cusj-10967	208	49	ov	ov	NOUN
cusj-10967	208	50	with	with	ADP
cusj-10967	208	51	immune	immune	ADJ
cusj-10967	208	52	signaling	signaling	NOUN
cusj-10967	208	53	.	.	PUNCT
cusj-10967	209	1	this	this	DET
cusj-10967	209	2	finding	finding	NOUN
cusj-10967	209	3	is	be	AUX
cusj-10967	209	4	interesting	interesting	ADJ
cusj-10967	209	5	but	but	CCONJ
cusj-10967	209	6	was	be	AUX
cusj-10967	209	7	not	not	PART
cusj-10967	209	8	experimentally	experimentally	ADV
cusj-10967	209	9	determined	determine	VERB
cusj-10967	209	10	to	to	ADP
cusj-10967	209	11	a	a	DET
cusj-10967	209	12	sufficient	sufficient	ADJ
cusj-10967	209	13	degree	degree	NOUN
cusj-10967	209	14	.	.	PUNCT
cusj-10967	210	1	combination	combination	NOUN
cusj-10967	210	2	therapy	therapy	NOUN
cusj-10967	210	3	using	use	VERB
cusj-10967	210	4	engineered	engineer	VERB
cusj-10967	210	5	ovs	ovs	NOUN
cusj-10967	210	6	and	and	CCONJ
cusj-10967	210	7	car	car	NOUN
cusj-10967	210	8	-	-	PUNCT
cusj-10967	210	9	t	t	NOUN
cusj-10967	210	10	cell	cell	NOUN
cusj-10967	210	11	therapy	therapy	NOUN
cusj-10967	210	12	can	can	AUX
cusj-10967	210	13	also	also	ADV
cusj-10967	210	14	be	be	AUX
cusj-10967	210	15	utilized	utilize	VERB
cusj-10967	210	16	to	to	PART
cusj-10967	210	17	overcome	overcome	VERB
cusj-10967	210	18	the	the	DET
cusj-10967	210	19	challenge	challenge	NOUN
cusj-10967	210	20	of	of	ADP
cusj-10967	210	21	homogenous	homogenous	ADJ
cusj-10967	210	22	expression	expression	NOUN
cusj-10967	210	23	of	of	ADP
cusj-10967	210	24	car	car	NOUN
cusj-10967	210	25	targets	target	NOUN
cusj-10967	210	26	.	.	PUNCT
cusj-10967	211	1	tumor	tumor	NOUN
cusj-10967	211	2	cells	cell	NOUN
cusj-10967	211	3	and	and	CCONJ
cusj-10967	211	4	healthy	healthy	ADJ
cusj-10967	211	5	cells	cell	NOUN
cusj-10967	211	6	both	both	PRON
cusj-10967	211	7	express	express	VERB
cusj-10967	211	8	certain	certain	ADJ
cusj-10967	211	9	car	car	NOUN
cusj-10967	211	10	targets	target	NOUN
cusj-10967	211	11	,	,	PUNCT
cusj-10967	211	12	which	which	PRON
cusj-10967	211	13	causes	cause	VERB
cusj-10967	211	14	car	car	NOUN
cusj-10967	211	15	-	-	PUNCT
cusj-10967	211	16	t	t	NOUN
cusj-10967	211	17	cell	cell	NOUN
cusj-10967	211	18	activity	activity	NOUN
cusj-10967	211	19	to	to	PART
cusj-10967	211	20	be	be	AUX
cusj-10967	211	21	nonspecific	nonspecific	ADJ
cusj-10967	211	22	to	to	ADP
cusj-10967	211	23	tumors	tumor	NOUN
cusj-10967	211	24	.	.	PUNCT
cusj-10967	212	1	park	park	NOUN
cusj-10967	212	2	and	and	CCONJ
cusj-10967	212	3	colleagues	colleague	NOUN
cusj-10967	212	4	developed	develop	VERB
cusj-10967	212	5	an	an	DET
cusj-10967	212	6	ov	ov	NOUN
cusj-10967	212	7	that	that	PRON
cusj-10967	212	8	causes	cause	VERB
cusj-10967	212	9	infected	infect	VERB
cusj-10967	212	10	tumor	tumor	NOUN
cusj-10967	212	11	cells	cell	NOUN
cusj-10967	212	12	to	to	PART
cusj-10967	212	13	express	express	VERB
cusj-10967	212	14	truncated	truncated	ADJ
cusj-10967	212	15	cd19	cd19	PROPN
cusj-10967	212	16	on	on	ADP
cusj-10967	212	17	their	their	PRON
cusj-10967	212	18	surface	surface	NOUN
cusj-10967	212	19	before	before	ADP
cusj-10967	212	20	lysing	lyse	VERB
cusj-10967	212	21	due	due	ADP
cusj-10967	212	22	to	to	ADP
cusj-10967	212	23	viral	viral	ADJ
cusj-10967	212	24	activity	activity	NOUN
cusj-10967	212	25	.	.	PUNCT
cusj-10967	213	1	car	car	NOUN
cusj-10967	213	2	-	-	PUNCT
cusj-10967	213	3	t	t	NOUN
cusj-10967	213	4	cells	cell	NOUN
cusj-10967	213	5	engineered	engineer	VERB
cusj-10967	213	6	with	with	ADP
cusj-10967	213	7	cd19	cd19	PROPN
cusj-10967	213	8	were	be	AUX
cusj-10967	213	9	drawn	draw	VERB
cusj-10967	213	10	to	to	ADP
cusj-10967	213	11	infected	infect	VERB
cusj-10967	213	12	cancer	cancer	NOUN
cusj-10967	213	13	cells	cell	NOUN
cusj-10967	213	14	due	due	ADJ
cusj-10967	213	15	to	to	ADP
cusj-10967	213	16	the	the	DET
cusj-10967	213	17	binding	bind	VERB
cusj-10967	213	18	mechanism	mechanism	NOUN
cusj-10967	213	19	of	of	ADP
cusj-10967	213	20	cd19	cd19	PROPN
cusj-10967	213	21	.	.	PUNCT
cusj-10967	213	22	native	native	PROPN
cusj-10967	213	23	t	t	PROPN
cusj-10967	213	24	cells	cell	NOUN
cusj-10967	213	25	were	be	AUX
cusj-10967	213	26	also	also	ADV
cusj-10967	213	27	signaled	signal	VERB
cusj-10967	213	28	and	and	CCONJ
cusj-10967	213	29	drawn	draw	VERB
cusj-10967	213	30	towards	towards	ADP
cusj-10967	213	31	the	the	DET
cusj-10967	213	32	tumor	tumor	NOUN
cusj-10967	213	33	.	.	PUNCT
cusj-10967	214	1	these	these	DET
cusj-10967	214	2	findings	finding	NOUN
cusj-10967	214	3	indicate	indicate	VERB
cusj-10967	214	4	that	that	DET
cusj-10967	214	5	car	car	NOUN
cusj-10967	214	6	-	-	PUNCT
cusj-10967	214	7	t	t	NOUN
cusj-10967	214	8	cell	cell	NOUN
cusj-10967	214	9	activity	activity	NOUN
cusj-10967	214	10	can	can	AUX
cusj-10967	214	11	be	be	AUX
cusj-10967	214	12	made	make	VERB
cusj-10967	214	13	specific	specific	ADJ
cusj-10967	214	14	through	through	ADP
cusj-10967	214	15	the	the	DET
cusj-10967	214	16	use	use	NOUN
cusj-10967	214	17	of	of	ADP
cusj-10967	214	18	ovs	ovs	NOUN
cusj-10967	214	19	to	to	PART
cusj-10967	214	20	express	express	VERB
cusj-10967	214	21	chimeric	chimeric	ADJ
cusj-10967	214	22	antigen	antigen	ADJ
cusj-10967	214	23	receptor	receptor	NOUN
cusj-10967	214	24	targets	target	NOUN
cusj-10967	214	25	in	in	ADP
cusj-10967	214	26	tumors.44	tumors.44	NOUN
cusj-10967	214	27	the	the	DET
cusj-10967	214	28	researchers	researcher	NOUN
cusj-10967	214	29	concluded	conclude	VERB
cusj-10967	214	30	that	that	SCONJ
cusj-10967	214	31	they	they	PRON
cusj-10967	214	32	had	have	AUX
cusj-10967	214	33	developed	develop	VERB
cusj-10967	214	34	a	a	DET
cusj-10967	214	35	method	method	NOUN
cusj-10967	214	36	of	of	ADP
cusj-10967	214	37	improving	improve	VERB
cusj-10967	214	38	the	the	DET
cusj-10967	214	39	tumor	tumor	NOUN
cusj-10967	214	40	targeting	target	VERB
cusj-10967	214	41	of	of	ADP
cusj-10967	214	42	car	car	NOUN
cusj-10967	214	43	-	-	PUNCT
cusj-10967	214	44	t	t	NOUN
cusj-10967	214	45	cells	cell	NOUN
cusj-10967	214	46	using	use	VERB
cusj-10967	214	47	ovs	ovs	NOUN
cusj-10967	214	48	and	and	CCONJ
cusj-10967	214	49	that	that	SCONJ
cusj-10967	214	50	this	this	DET
cusj-10967	214	51	interaction	interaction	NOUN
cusj-10967	214	52	had	have	VERB
cusj-10967	214	53	potential	potential	ADJ
cusj-10967	214	54	therapeutic	therapeutic	ADJ
cusj-10967	214	55	applications	application	NOUN
cusj-10967	214	56	in	in	ADP
cusj-10967	214	57	the	the	DET
cusj-10967	214	58	future	future	NOUN
cusj-10967	214	59	.	.	PUNCT
cusj-10967	215	1	combination	combination	NOUN
cusj-10967	215	2	therapy	therapy	NOUN
cusj-10967	215	3	utilizing	utilize	VERB
cusj-10967	215	4	oncolytic	oncolytic	PROPN
cusj-10967	215	5	columbia	columbia	PROPN
cusj-10967	215	6	undergraduate	undergraduate	PROPN
cusj-10967	215	7	science	science	PROPN
cusj-10967	215	8	journal	journal	PROPN
cusj-10967	215	9	vol	vol	NOUN
cusj-10967	215	10	.	.	PROPN
cusj-10967	215	11	18	18	NUM
cusj-10967	215	12	,	,	PUNCT
cusj-10967	215	13	2024	2024	NUM
cusj-10967	215	14	manjila	manjila	PROPN
cusj-10967	215	15	virotherapy	virotherapy	NOUN
cusj-10967	215	16	and	and	CCONJ
cusj-10967	215	17	other	other	ADJ
cusj-10967	215	18	cancer	cancer	NOUN
cusj-10967	215	19	therapeutic	therapeutic	ADJ
cusj-10967	215	20	strategies	strategy	NOUN
cusj-10967	215	21	,	,	PUNCT
cusj-10967	215	22	such	such	ADJ
cusj-10967	215	23	as	as	ADP
cusj-10967	215	24	car	car	NOUN
cusj-10967	215	25	-	-	PUNCT
cusj-10967	215	26	t	t	NOUN
cusj-10967	215	27	cell	cell	NOUN
cusj-10967	215	28	therapy	therapy	NOUN
cusj-10967	215	29	,	,	PUNCT
cusj-10967	215	30	holds	hold	VERB
cusj-10967	215	31	significant	significant	ADJ
cusj-10967	215	32	potential	potential	NOUN
cusj-10967	215	33	for	for	ADP
cusj-10967	215	34	improving	improve	VERB
cusj-10967	215	35	patient	patient	ADJ
cusj-10967	215	36	outcomes	outcome	NOUN
cusj-10967	215	37	.	.	PUNCT
cusj-10967	216	1	multiple	multiple	ADJ
cusj-10967	216	2	therapeutic	therapeutic	ADJ
cusj-10967	216	3	strategies	strategy	NOUN
cusj-10967	216	4	that	that	PRON
cusj-10967	216	5	can	can	AUX
cusj-10967	216	6	function	function	VERB
cusj-10967	216	7	effectively	effectively	ADV
cusj-10967	216	8	could	could	AUX
cusj-10967	216	9	have	have	VERB
cusj-10967	216	10	additive	additive	ADJ
cusj-10967	216	11	antitumor	antitumor	NOUN
cusj-10967	216	12	effects	effect	NOUN
cusj-10967	216	13	and	and	CCONJ
cusj-10967	216	14	prolong	prolong	VERB
cusj-10967	216	15	life	life	NOUN
cusj-10967	216	16	or	or	CCONJ
cusj-10967	216	17	destroy	destroy	VERB
cusj-10967	216	18	tumors	tumor	NOUN
cusj-10967	216	19	.	.	PUNCT
cusj-10967	217	1	additionally	additionally	ADV
cusj-10967	217	2	,	,	PUNCT
cusj-10967	217	3	therapeutics	therapeutic	NOUN
cusj-10967	217	4	that	that	PRON
cusj-10967	217	5	do	do	AUX
cusj-10967	217	6	not	not	PART
cusj-10967	217	7	cause	cause	VERB
cusj-10967	217	8	severe	severe	ADJ
cusj-10967	217	9	side	side	NOUN
cusj-10967	217	10	effects	effect	NOUN
cusj-10967	217	11	could	could	AUX
cusj-10967	217	12	be	be	AUX
cusj-10967	217	13	implemented	implement	VERB
cusj-10967	217	14	in	in	ADP
cusj-10967	217	15	the	the	DET
cusj-10967	217	16	clinical	clinical	ADJ
cusj-10967	217	17	setting	setting	NOUN
cusj-10967	217	18	without	without	ADP
cusj-10967	217	19	causing	cause	VERB
cusj-10967	217	20	great	great	ADJ
cusj-10967	217	21	discomfort	discomfort	NOUN
cusj-10967	217	22	or	or	CCONJ
cusj-10967	217	23	additional	additional	ADJ
cusj-10967	217	24	risks	risk	NOUN
cusj-10967	217	25	for	for	ADP
cusj-10967	217	26	patients	patient	NOUN
cusj-10967	217	27	.	.	PUNCT
cusj-10967	218	1	currently	currently	ADV
cusj-10967	218	2	,	,	PUNCT
cusj-10967	218	3	oncolytic	oncolytic	ADJ
cusj-10967	218	4	viruses	virus	NOUN
cusj-10967	218	5	are	be	AUX
cusj-10967	218	6	entering	enter	VERB
cusj-10967	218	7	clinical	clinical	ADJ
cusj-10967	218	8	use	use	NOUN
cusj-10967	218	9	and	and	CCONJ
cusj-10967	218	10	car	car	NOUN
cusj-10967	218	11	-	-	PUNCT
cusj-10967	218	12	t	t	NOUN
cusj-10967	218	13	cell	cell	NOUN
cusj-10967	218	14	therapy	therapy	NOUN
cusj-10967	218	15	has	have	AUX
cusj-10967	218	16	been	be	AUX
cusj-10967	218	17	in	in	ADP
cusj-10967	218	18	use	use	NOUN
cusj-10967	218	19	for	for	ADP
cusj-10967	218	20	treating	treat	VERB
cusj-10967	218	21	patients	patient	NOUN
cusj-10967	218	22	suffering	suffer	VERB
cusj-10967	218	23	from	from	ADP
cusj-10967	218	24	blood	blood	NOUN
cusj-10967	218	25	cancers	cancer	NOUN
cusj-10967	218	26	.	.	PUNCT
cusj-10967	219	1	it	it	PRON
cusj-10967	219	2	is	be	AUX
cusj-10967	219	3	reasonable	reasonable	ADJ
cusj-10967	219	4	that	that	SCONJ
cusj-10967	219	5	two	two	NUM
cusj-10967	219	6	clinically	clinically	ADV
cusj-10967	219	7	approved	approve	VERB
cusj-10967	219	8	treatment	treatment	NOUN
cusj-10967	219	9	strategies	strategy	NOUN
cusj-10967	219	10	could	could	AUX
cusj-10967	219	11	be	be	AUX
cusj-10967	219	12	utilized	utilize	VERB
cusj-10967	219	13	as	as	ADP
cusj-10967	219	14	a	a	DET
cusj-10967	219	15	combined	combined	ADJ
cusj-10967	219	16	treatment	treatment	NOUN
cusj-10967	219	17	in	in	ADP
cusj-10967	219	18	the	the	DET
cusj-10967	219	19	future	future	NOUN
cusj-10967	219	20	.	.	PUNCT
cusj-10967	220	1	conclusion	conclusion	NOUN
cusj-10967	220	2	significant	significant	ADJ
cusj-10967	220	3	advances	advance	NOUN
cusj-10967	220	4	have	have	AUX
cusj-10967	220	5	been	be	AUX
cusj-10967	220	6	made	make	VERB
cusj-10967	220	7	in	in	ADP
cusj-10967	220	8	research	research	NOUN
cusj-10967	220	9	on	on	ADP
cusj-10967	220	10	engineered	engineer	VERB
cusj-10967	220	11	oncolytic	oncolytic	ADJ
cusj-10967	220	12	viruses	virus	NOUN
cusj-10967	220	13	in	in	ADP
cusj-10967	220	14	the	the	DET
cusj-10967	220	15	last	last	ADJ
cusj-10967	220	16	five	five	NUM
cusj-10967	220	17	years	year	NOUN
cusj-10967	220	18	.	.	PUNCT
cusj-10967	221	1	several	several	ADJ
cusj-10967	221	2	studies	study	NOUN
cusj-10967	221	3	have	have	AUX
cusj-10967	221	4	led	lead	VERB
cusj-10967	221	5	to	to	ADP
cusj-10967	221	6	the	the	DET
cusj-10967	221	7	development	development	NOUN
cusj-10967	221	8	of	of	ADP
cusj-10967	221	9	novel	novel	ADJ
cusj-10967	221	10	ovs	ovs	NOUN
cusj-10967	221	11	which	which	PRON
cusj-10967	221	12	have	have	AUX
cusj-10967	221	13	demonstrated	demonstrate	VERB
cusj-10967	221	14	antitumor	antitumor	PROPN
cusj-10967	221	15	effectiveness	effectiveness	NOUN
cusj-10967	221	16	,	,	PUNCT
cusj-10967	221	17	including	include	VERB
cusj-10967	221	18	in	in	ADP
cusj-10967	221	19	vivo	vivo	NOUN
cusj-10967	221	20	.	.	PUNCT
cusj-10967	222	1	researchers	researcher	NOUN
cusj-10967	222	2	have	have	AUX
cusj-10967	222	3	also	also	ADV
cusj-10967	222	4	taken	take	VERB
cusj-10967	222	5	many	many	ADJ
cusj-10967	222	6	different	different	ADJ
cusj-10967	222	7	approaches	approach	NOUN
cusj-10967	222	8	to	to	ADP
cusj-10967	222	9	developing	develop	VERB
cusj-10967	222	10	engineered	engineer	VERB
cusj-10967	222	11	oncolytic	oncolytic	ADJ
cusj-10967	222	12	viruses	virus	NOUN
cusj-10967	222	13	.	.	PUNCT
cusj-10967	223	1	tumor	tumor	NOUN
cusj-10967	223	2	microenvironment	microenvironment	NOUN
cusj-10967	223	3	remodeling	remodeling	NOUN
cusj-10967	223	4	has	have	AUX
cusj-10967	223	5	been	be	AUX
cusj-10967	223	6	investigated	investigate	VERB
cusj-10967	223	7	as	as	ADP
cusj-10967	223	8	a	a	DET
cusj-10967	223	9	method	method	NOUN
cusj-10967	223	10	of	of	ADP
cusj-10967	223	11	improving	improve	VERB
cusj-10967	223	12	immune	immune	ADJ
cusj-10967	223	13	cell	cell	NOUN
cusj-10967	223	14	infiltration	infiltration	NOUN
cusj-10967	223	15	of	of	ADP
cusj-10967	223	16	tumors	tumor	NOUN
cusj-10967	223	17	.	.	PUNCT
cusj-10967	224	1	genetic	genetic	ADJ
cusj-10967	224	2	and	and	CCONJ
cusj-10967	224	3	structural	structural	ADJ
cusj-10967	224	4	modifications	modification	NOUN
cusj-10967	224	5	have	have	AUX
cusj-10967	224	6	been	be	AUX
cusj-10967	224	7	utilized	utilize	VERB
cusj-10967	224	8	to	to	PART
cusj-10967	224	9	enhance	enhance	VERB
cusj-10967	224	10	the	the	DET
cusj-10967	224	11	antitumor	antitumor	PROPN
cusj-10967	224	12	effectiveness	effectiveness	NOUN
cusj-10967	224	13	of	of	ADP
cusj-10967	224	14	ovs	ovs	NOUN
cusj-10967	224	15	.	.	PUNCT
cusj-10967	225	1	specialized	specialized	ADJ
cusj-10967	225	2	ovs	ovs	PROPN
cusj-10967	225	3	have	have	AUX
cusj-10967	225	4	entered	enter	VERB
cusj-10967	225	5	development	development	NOUN
cusj-10967	225	6	for	for	ADP
cusj-10967	225	7	the	the	DET
cusj-10967	225	8	treatment	treatment	NOUN
cusj-10967	225	9	of	of	ADP
cusj-10967	225	10	slow	slow	ADV
cusj-10967	225	11	-	-	PUNCT
cusj-10967	225	12	growing	grow	VERB
cusj-10967	225	13	tumors	tumor	NOUN
cusj-10967	225	14	and	and	CCONJ
cusj-10967	225	15	rare	rare	ADJ
cusj-10967	225	16	cancers	cancer	NOUN
cusj-10967	225	17	.	.	PUNCT
cusj-10967	226	1	the	the	DET
cusj-10967	226	2	targeting	targeting	NOUN
cusj-10967	226	3	and	and	CCONJ
cusj-10967	226	4	infection	infection	NOUN
cusj-10967	226	5	of	of	ADP
cusj-10967	226	6	tumor	tumor	NOUN
cusj-10967	226	7	cells	cell	NOUN
cusj-10967	226	8	has	have	AUX
cusj-10967	226	9	been	be	AUX
cusj-10967	226	10	improved	improve	VERB
cusj-10967	226	11	through	through	ADP
cusj-10967	226	12	signaling	signal	VERB
cusj-10967	226	13	and	and	CCONJ
cusj-10967	226	14	receptor	receptor	NOUN
cusj-10967	226	15	upregulation	upregulation	NOUN
cusj-10967	226	16	.	.	PUNCT
cusj-10967	227	1	oncolytic	oncolytic	ADJ
cusj-10967	227	2	virotherapy	virotherapy	PROPN
cusj-10967	227	3	is	be	AUX
cusj-10967	227	4	effective	effective	ADJ
cusj-10967	227	5	in	in	ADP
cusj-10967	227	6	combined	combined	ADJ
cusj-10967	227	7	treatment	treatment	NOUN
cusj-10967	227	8	with	with	ADP
cusj-10967	227	9	car	car	NOUN
cusj-10967	227	10	-	-	PUNCT
cusj-10967	227	11	t	t	NOUN
cusj-10967	227	12	cell	cell	NOUN
cusj-10967	227	13	therapy	therapy	NOUN
cusj-10967	227	14	.	.	PUNCT
cusj-10967	228	1	these	these	DET
cusj-10967	228	2	approaches	approach	NOUN
cusj-10967	228	3	address	address	VERB
cusj-10967	228	4	a	a	DET
cusj-10967	228	5	variety	variety	NOUN
cusj-10967	228	6	of	of	ADP
cusj-10967	228	7	issues	issue	NOUN
cusj-10967	228	8	and	and	CCONJ
cusj-10967	228	9	challenges	challenge	NOUN
cusj-10967	228	10	in	in	ADP
cusj-10967	228	11	the	the	DET
cusj-10967	228	12	development	development	NOUN
cusj-10967	228	13	and	and	CCONJ
cusj-10967	228	14	refinement	refinement	NOUN
cusj-10967	228	15	of	of	ADP
cusj-10967	228	16	ovs	ovs	NOUN
cusj-10967	228	17	for	for	ADP
cusj-10967	228	18	potential	potential	ADJ
cusj-10967	228	19	clinical	clinical	ADJ
cusj-10967	228	20	treatment	treatment	NOUN
cusj-10967	228	21	.	.	PUNCT
cusj-10967	229	1	outside	outside	ADP
cusj-10967	229	2	the	the	DET
cusj-10967	229	3	direct	direct	ADJ
cusj-10967	229	4	development	development	NOUN
cusj-10967	229	5	of	of	ADP
cusj-10967	229	6	ovs	ovs	NOUN
cusj-10967	229	7	with	with	ADP
cusj-10967	229	8	genetic	genetic	ADJ
cusj-10967	229	9	and	and	CCONJ
cusj-10967	229	10	structural	structural	ADJ
cusj-10967	229	11	modifications	modification	NOUN
cusj-10967	229	12	,	,	PUNCT
cusj-10967	229	13	researchers	researcher	NOUN
cusj-10967	229	14	have	have	AUX
cusj-10967	229	15	approached	approach	VERB
cusj-10967	229	16	the	the	DET
cusj-10967	229	17	question	question	NOUN
cusj-10967	229	18	of	of	ADP
cusj-10967	229	19	engineered	engineer	VERB
cusj-10967	229	20	ov	ov	PROPN
cusj-10967	229	21	implementation	implementation	NOUN
cusj-10967	229	22	in	in	ADP
cusj-10967	229	23	a	a	DET
cusj-10967	229	24	number	number	NOUN
cusj-10967	229	25	of	of	ADP
cusj-10967	229	26	ways	way	NOUN
cusj-10967	229	27	.	.	PUNCT
cusj-10967	230	1	engineering	engineering	NOUN
cusj-10967	230	2	experts	expert	NOUN
cusj-10967	230	3	have	have	AUX
cusj-10967	230	4	applied	apply	VERB
cusj-10967	230	5	their	their	PRON
cusj-10967	230	6	expertise	expertise	NOUN
cusj-10967	230	7	to	to	ADP
cusj-10967	230	8	the	the	DET
cusj-10967	230	9	delivery	delivery	NOUN
cusj-10967	230	10	of	of	ADP
cusj-10967	230	11	ovs	ovs	NOUN
cusj-10967	230	12	,	,	PUNCT
cusj-10967	230	13	as	as	ADP
cusj-10967	230	14	in	in	ADP
cusj-10967	230	15	the	the	DET
cusj-10967	230	16	application	application	NOUN
cusj-10967	230	17	of	of	ADP
cusj-10967	230	18	control	control	NOUN
cusj-10967	230	19	theory	theory	NOUN
cusj-10967	230	20	for	for	ADP
cusj-10967	230	21	the	the	DET
cusj-10967	230	22	regulation	regulation	NOUN
cusj-10967	230	23	of	of	ADP
cusj-10967	230	24	ov	ov	PROPN
cusj-10967	230	25	dosage.45	dosage.45	VERB
cusj-10967	230	26	theoretical	theoretical	ADJ
cusj-10967	230	27	biologists	biologist	NOUN
cusj-10967	230	28	have	have	AUX
cusj-10967	230	29	also	also	ADV
cusj-10967	230	30	approached	approach	VERB
cusj-10967	230	31	the	the	DET
cusj-10967	230	32	question	question	NOUN
cusj-10967	230	33	of	of	ADP
cusj-10967	230	34	implementation	implementation	NOUN
cusj-10967	230	35	through	through	ADP
cusj-10967	230	36	mathematical	mathematical	ADJ
cusj-10967	230	37	models	model	NOUN
cusj-10967	230	38	,	,	PUNCT
cusj-10967	230	39	such	such	ADJ
cusj-10967	230	40	as	as	ADP
cusj-10967	230	41	a	a	DET
cusj-10967	230	42	voronoi	voronoi	ADJ
cusj-10967	230	43	cell	cell	NOUN
cusj-10967	230	44	-	-	PUNCT
cusj-10967	230	45	based	base	VERB
cusj-10967	230	46	model	model	NOUN
cusj-10967	230	47	for	for	ADP
cusj-10967	230	48	viral	viral	ADJ
cusj-10967	230	49	spread	spread	NOUN
cusj-10967	230	50	in	in	ADP
cusj-10967	230	51	tumors.46	tumors.46	NOUN
cusj-10967	230	52	these	these	DET
cusj-10967	230	53	types	type	NOUN
cusj-10967	230	54	of	of	ADP
cusj-10967	230	55	studies	study	NOUN
cusj-10967	230	56	contribute	contribute	VERB
cusj-10967	230	57	additional	additional	ADJ
cusj-10967	230	58	information	information	NOUN
cusj-10967	230	59	towards	towards	ADP
cusj-10967	230	60	the	the	DET
cusj-10967	230	61	larger	large	ADJ
cusj-10967	230	62	effort	effort	NOUN
cusj-10967	230	63	to	to	PART
cusj-10967	230	64	optimize	optimize	VERB
cusj-10967	230	65	and	and	CCONJ
cusj-10967	230	66	implement	implement	VERB
cusj-10967	230	67	ovs	ovs	NOUN
cusj-10967	230	68	in	in	ADP
cusj-10967	230	69	the	the	DET
cusj-10967	230	70	clinical	clinical	ADJ
cusj-10967	230	71	setting	setting	NOUN
cusj-10967	230	72	.	.	PUNCT
cusj-10967	231	1	some	some	DET
cusj-10967	231	2	researchers	researcher	NOUN
cusj-10967	231	3	have	have	AUX
cusj-10967	231	4	also	also	ADV
cusj-10967	231	5	published	publish	VERB
cusj-10967	231	6	the	the	DET
cusj-10967	231	7	specific	specific	ADJ
cusj-10967	231	8	methods	method	NOUN
cusj-10967	231	9	they	they	PRON
cusj-10967	231	10	used	use	VERB
cusj-10967	231	11	to	to	PART
cusj-10967	231	12	engineer	engineer	VERB
cusj-10967	231	13	ovs	ovs	NOUN
cusj-10967	231	14	and	and	CCONJ
cusj-10967	231	15	quantify	quantify	VERB
cusj-10967	231	16	them	they	PRON
cusj-10967	231	17	,	,	PUNCT
cusj-10967	231	18	allowing	allow	VERB
cusj-10967	231	19	others	other	NOUN
cusj-10967	231	20	to	to	PART
cusj-10967	231	21	pursue	pursue	VERB
cusj-10967	231	22	their	their	PRON
cusj-10967	231	23	own	own	ADJ
cusj-10967	231	24	virus	virus	NOUN
cusj-10967	231	25	engineering	engineering	NOUN
cusj-10967	231	26	projects.47,48,49	projects.47,48,49	NOUN
cusj-10967	231	27	clinical	clinical	ADJ
cusj-10967	231	28	trials	trial	NOUN
cusj-10967	231	29	in	in	ADP
cusj-10967	231	30	veterinary	veterinary	ADJ
cusj-10967	231	31	medicine	medicine	NOUN
cusj-10967	231	32	are	be	AUX
cusj-10967	231	33	also	also	ADV
cusj-10967	231	34	being	be	AUX
cusj-10967	231	35	conducted	conduct	VERB
cusj-10967	231	36	,	,	PUNCT
cusj-10967	231	37	with	with	ADP
cusj-10967	231	38	the	the	DET
cusj-10967	231	39	same	same	ADJ
cusj-10967	231	40	types	type	NOUN
cusj-10967	231	41	of	of	ADP
cusj-10967	231	42	cancers	cancer	NOUN
cusj-10967	231	43	being	be	AUX
cusj-10967	231	44	treated	treat	VERB
cusj-10967	231	45	in	in	ADP
cusj-10967	231	46	animals	animal	NOUN
cusj-10967	231	47	as	as	ADP
cusj-10967	231	48	in	in	ADP
cusj-10967	231	49	humans.50	humans.50	PROPN
cusj-10967	231	50	this	this	DET
cusj-10967	231	51	variety	variety	NOUN
cusj-10967	231	52	of	of	ADP
cusj-10967	231	53	research	research	NOUN
cusj-10967	231	54	approaches	approach	NOUN
cusj-10967	231	55	is	be	AUX
cusj-10967	231	56	additional	additional	ADJ
cusj-10967	231	57	evidence	evidence	NOUN
cusj-10967	231	58	for	for	ADP
cusj-10967	231	59	the	the	DET
cusj-10967	231	60	interest	interest	NOUN
cusj-10967	231	61	engineered	engineer	VERB
cusj-10967	231	62	ovs	ovs	NOUN
cusj-10967	231	63	are	be	AUX
cusj-10967	231	64	gaining	gain	VERB
cusj-10967	231	65	.	.	PUNCT
cusj-10967	232	1	in	in	ADP
cusj-10967	232	2	conclusion	conclusion	NOUN
cusj-10967	232	3	,	,	PUNCT
cusj-10967	232	4	ovs	ovs	NOUN
cusj-10967	232	5	demonstrate	demonstrate	VERB
cusj-10967	232	6	significant	significant	ADJ
cusj-10967	232	7	potential	potential	NOUN
cusj-10967	232	8	for	for	ADP
cusj-10967	232	9	treating	treat	VERB
cusj-10967	232	10	cancers	cancer	NOUN
cusj-10967	232	11	with	with	ADP
cusj-10967	232	12	efficacy	efficacy	NOUN
cusj-10967	232	13	and	and	CCONJ
cusj-10967	232	14	safety	safety	NOUN
cusj-10967	232	15	.	.	PUNCT
cusj-10967	233	1	ovs	ovs	PROPN
cusj-10967	233	2	can	can	AUX
cusj-10967	233	3	be	be	AUX
cusj-10967	233	4	engineered	engineer	VERB
cusj-10967	233	5	to	to	PART
cusj-10967	233	6	deliver	deliver	VERB
cusj-10967	233	7	signaling	signal	VERB
cusj-10967	233	8	molecules	molecule	NOUN
cusj-10967	233	9	to	to	ADP
cusj-10967	233	10	cancer	cancer	NOUN
cusj-10967	233	11	cells	cell	NOUN
cusj-10967	233	12	,	,	PUNCT
cusj-10967	233	13	facilitate	facilitate	ADJ
cusj-10967	233	14	immune	immune	ADJ
cusj-10967	233	15	cell	cell	NOUN
cusj-10967	233	16	infiltration	infiltration	NOUN
cusj-10967	233	17	of	of	ADP
cusj-10967	233	18	tumors	tumor	NOUN
cusj-10967	233	19	,	,	PUNCT
cusj-10967	233	20	and	and	CCONJ
cusj-10967	233	21	upregulate	upregulate	VERB
cusj-10967	233	22	immune	immune	ADJ
cusj-10967	233	23	response	response	NOUN
cusj-10967	233	24	to	to	ADP
cusj-10967	233	25	tumor	tumor	NOUN
cusj-10967	233	26	growth	growth	NOUN
cusj-10967	233	27	.	.	PUNCT
cusj-10967	234	1	there	there	PRON
cusj-10967	234	2	are	be	VERB
cusj-10967	234	3	many	many	ADJ
cusj-10967	234	4	viruses	virus	NOUN
cusj-10967	234	5	and	and	CCONJ
cusj-10967	234	6	viral	viral	ADJ
cusj-10967	234	7	modifications	modification	NOUN
cusj-10967	234	8	that	that	PRON
cusj-10967	234	9	are	be	AUX
cusj-10967	234	10	suitable	suitable	ADJ
cusj-10967	234	11	candidates	candidate	NOUN
cusj-10967	234	12	for	for	ADP
cusj-10967	234	13	engineering	engineer	VERB
cusj-10967	234	14	into	into	ADP
cusj-10967	234	15	ovs	ovs	NOUN
cusj-10967	234	16	.	.	PUNCT
cusj-10967	235	1	cancer	cancer	NOUN
cusj-10967	235	2	treatment	treatment	NOUN
cusj-10967	235	3	strategies	strategy	NOUN
cusj-10967	235	4	such	such	ADJ
cusj-10967	235	5	as	as	ADP
cusj-10967	235	6	chemotherapy	chemotherapy	NOUN
cusj-10967	235	7	often	often	ADV
cusj-10967	235	8	cause	cause	VERB
cusj-10967	235	9	systemic	systemic	ADJ
cusj-10967	235	10	symptoms	symptom	NOUN
cusj-10967	235	11	and	and	CCONJ
cusj-10967	235	12	side	side	NOUN
cusj-10967	235	13	effects	effect	NOUN
cusj-10967	235	14	that	that	PRON
cusj-10967	235	15	are	be	AUX
cusj-10967	235	16	very	very	ADV
cusj-10967	235	17	unpleasant	unpleasant	ADJ
cusj-10967	235	18	for	for	ADP
cusj-10967	235	19	patients	patient	NOUN
cusj-10967	235	20	.	.	PUNCT
cusj-10967	236	1	these	these	DET
cusj-10967	236	2	symptoms	symptom	NOUN
cusj-10967	236	3	may	may	AUX
cusj-10967	236	4	be	be	AUX
cusj-10967	236	5	mitigated	mitigate	VERB
cusj-10967	236	6	by	by	ADP
cusj-10967	236	7	ovs	ovs	NOUN
cusj-10967	236	8	since	since	SCONJ
cusj-10967	236	9	the	the	DET
cusj-10967	236	10	viruses	virus	NOUN
cusj-10967	236	11	can	can	AUX
cusj-10967	236	12	be	be	AUX
cusj-10967	236	13	engineered	engineer	VERB
cusj-10967	236	14	to	to	PART
cusj-10967	236	15	selectively	selectively	ADV
cusj-10967	236	16	target	target	VERB
cusj-10967	236	17	tumors	tumor	NOUN
cusj-10967	236	18	and	and	CCONJ
cusj-10967	236	19	utilize	utilize	VERB
cusj-10967	236	20	safe	safe	ADJ
cusj-10967	236	21	molecular	molecular	ADJ
cusj-10967	236	22	components	component	NOUN
cusj-10967	236	23	.	.	PUNCT
cusj-10967	237	1	as	as	ADP
cusj-10967	237	2	more	more	ADJ
cusj-10967	237	3	ovs	ovs	NOUN
cusj-10967	237	4	are	be	AUX
cusj-10967	237	5	engineered	engineer	VERB
cusj-10967	237	6	and	and	CCONJ
cusj-10967	237	7	move	move	VERB
cusj-10967	237	8	into	into	ADP
cusj-10967	237	9	clinical	clinical	ADJ
cusj-10967	237	10	trials	trial	NOUN
cusj-10967	237	11	,	,	PUNCT
cusj-10967	237	12	there	there	PRON
cusj-10967	237	13	will	will	AUX
cusj-10967	237	14	likely	likely	ADV
cusj-10967	237	15	be	be	AUX
cusj-10967	237	16	a	a	DET
cusj-10967	237	17	greater	great	ADJ
cusj-10967	237	18	number	number	NOUN
cusj-10967	237	19	of	of	ADP
cusj-10967	237	20	ov	ov	PROPN
cusj-10967	237	21	therapeutics	therapeutic	NOUN
cusj-10967	237	22	available	available	ADJ
cusj-10967	237	23	for	for	ADP
cusj-10967	237	24	medical	medical	ADJ
cusj-10967	237	25	use	use	NOUN
cusj-10967	237	26	in	in	ADP
cusj-10967	237	27	the	the	DET
cusj-10967	237	28	next	next	ADJ
cusj-10967	237	29	decade	decade	NOUN
cusj-10967	237	30	.	.	PUNCT
cusj-10967	238	1	the	the	DET
cusj-10967	238	2	future	future	NOUN
cusj-10967	238	3	of	of	ADP
cusj-10967	238	4	oncolytic	oncolytic	ADJ
cusj-10967	238	5	virus	virus	NOUN
cusj-10967	238	6	research	research	NOUN
cusj-10967	238	7	appears	appear	VERB
cusj-10967	238	8	very	very	ADV
cusj-10967	238	9	promising	promising	ADJ
cusj-10967	238	10	as	as	SCONJ
cusj-10967	238	11	it	it	PRON
cusj-10967	238	12	provides	provide	VERB
cusj-10967	238	13	hope	hope	NOUN
cusj-10967	238	14	for	for	ADP
cusj-10967	238	15	the	the	DET
cusj-10967	238	16	development	development	NOUN
cusj-10967	238	17	of	of	ADP
cusj-10967	238	18	meaningful	meaningful	ADJ
cusj-10967	238	19	cancer	cancer	NOUN
cusj-10967	238	20	therapeutics	therapeutic	NOUN
cusj-10967	238	21	.	.	PUNCT
cusj-10967	239	1	author	author	NOUN
cusj-10967	239	2	information	information	NOUN
cusj-10967	239	3	corresponding	correspond	VERB
cusj-10967	239	4	author	author	NOUN
cusj-10967	239	5	nihal	nihal	PROPN
cusj-10967	239	6	manjila	manjila	PROPN
cusj-10967	239	7	nihal_manjila@hms.harvard.edu	nihal_manjila@hms.harvard.edu	PART
cusj-10967	239	8	acknowledgements	acknowledgement	NOUN
cusj-10967	239	9	the	the	DET
cusj-10967	239	10	author	author	NOUN
cusj-10967	239	11	expresses	express	VERB
cusj-10967	239	12	his	his	PRON
cusj-10967	239	13	gratitude	gratitude	NOUN
cusj-10967	239	14	to	to	ADP
cusj-10967	239	15	professor	professor	PROPN
cusj-10967	239	16	phoebe	phoebe	PROPN
cusj-10967	239	17	stewart	stewart	PROPN
cusj-10967	239	18	(	(	PUNCT
cusj-10967	239	19	department	department	PROPN
cusj-10967	239	20	of	of	ADP
cusj-10967	239	21	pharmacology	pharmacology	NOUN
cusj-10967	239	22	,	,	PUNCT
cusj-10967	239	23	case	case	NOUN
cusj-10967	239	24	western	western	PROPN
cusj-10967	239	25	reserve	reserve	PROPN
cusj-10967	239	26	university	university	PROPN
cusj-10967	239	27	school	school	NOUN
cusj-10967	239	28	of	of	ADP
cusj-10967	239	29	medicine	medicine	NOUN
cusj-10967	239	30	)	)	PUNCT
cusj-10967	239	31	for	for	ADP
cusj-10967	239	32	guidance	guidance	NOUN
cusj-10967	239	33	and	and	CCONJ
cusj-10967	239	34	feedback	feedback	NOUN
cusj-10967	239	35	in	in	ADP
cusj-10967	239	36	the	the	DET
cusj-10967	239	37	preparation	preparation	NOUN
cusj-10967	239	38	of	of	ADP
cusj-10967	239	39	the	the	DET
cusj-10967	239	40	article	article	NOUN
cusj-10967	239	41	.	.	PUNCT
cusj-10967	240	1	columbia	columbia	PROPN
cusj-10967	240	2	undergraduate	undergraduate	PROPN
cusj-10967	240	3	science	science	PROPN
cusj-10967	240	4	journal	journal	PROPN
cusj-10967	240	5	vol	vol	NOUN
cusj-10967	240	6	.	.	PROPN
cusj-10967	240	7	18	18	NUM
cusj-10967	240	8	,	,	PUNCT
cusj-10967	240	9	2024	2024	NUM
cusj-10967	240	10	manjila	manjila	PROPN
cusj-10967	240	11	abbreviations	abbreviation	NOUN
cusj-10967	240	12	ov	ov	PROPN
cusj-10967	240	13	:	:	PUNCT
cusj-10967	240	14	oncolytic	oncolytic	ADJ
cusj-10967	240	15	virotherapy	virotherapy	PROPN
cusj-10967	240	16	hsv	hsv	PROPN
cusj-10967	240	17	:	:	PUNCT
cusj-10967	240	18	herpes	herpe	NOUN
cusj-10967	240	19	simplex	simplex	NOUN
cusj-10967	240	20	virus	virus	NOUN
cusj-10967	240	21	car	car	NOUN
cusj-10967	240	22	-	-	PUNCT
cusj-10967	240	23	t	t	NOUN
cusj-10967	240	24	:	:	PUNCT
cusj-10967	241	1	chimeric	chimeric	ADJ
cusj-10967	241	2	antigen	antigen	ADJ
cusj-10967	241	3	receptor	receptor	NOUN
cusj-10967	241	4	t	t	PROPN
cusj-10967	241	5	nk	nk	PROPN
cusj-10967	241	6	:	:	PUNCT
cusj-10967	241	7	natural	natural	ADJ
cusj-10967	241	8	killer	killer	NOUN
cusj-10967	241	9	t	t	PROPN
cusj-10967	241	10	-	-	PUNCT
cusj-10967	241	11	vec	vec	PROPN
cusj-10967	241	12	:	:	PUNCT
cusj-10967	241	13	talimogene	talimogene	PROPN
cusj-10967	241	14	laherparepvec	laherparepvec	PROPN
cusj-10967	241	15	trail	trail	NOUN
cusj-10967	241	16	:	:	PUNCT
cusj-10967	241	17	tumor	tumor	NOUN
cusj-10967	241	18	necrosis	necrosis	NOUN
cusj-10967	241	19	factor	factor	NOUN
cusj-10967	241	20	-	-	PUNCT
cusj-10967	241	21	related	relate	VERB
cusj-10967	241	22	apoptosis	apoptosis	NOUN
cusj-10967	241	23	-	-	PUNCT
cusj-10967	241	24	inducing	induce	VERB
cusj-10967	241	25	ligand	ligand	NOUN
cusj-10967	241	26	htert	htert	NOUN
cusj-10967	241	27	:	:	PUNCT
cusj-10967	241	28	human	human	ADJ
cusj-10967	241	29	telomerase	telomerase	NOUN
cusj-10967	241	30	reverse	reverse	VERB
cusj-10967	241	31	transcriptase	transcriptase	NOUN
cusj-10967	241	32	ccl5	ccl5	PROPN
cusj-10967	241	33	:	:	PUNCT
cusj-10967	241	34	chemokine	chemokine	PROPN
cusj-10967	241	35	ligand	ligand	NOUN
cusj-10967	241	36	5	5	NUM
cusj-10967	241	37	ccr5	ccr5	NOUN
cusj-10967	241	38	:	:	PUNCT
cusj-10967	241	39	chemokine	chemokine	ADJ
cusj-10967	241	40	receptor	receptor	NOUN
cusj-10967	241	41	type	type	NOUN
cusj-10967	241	42	5	5	NUM
cusj-10967	241	43	pd1	pd1	NOUN
cusj-10967	241	44	:	:	PUNCT
cusj-10967	241	45	programmed	program	VERB
cusj-10967	241	46	cell	cell	NOUN
cusj-10967	241	47	death	death	NOUN
cusj-10967	241	48	protein	protein	NOUN
cusj-10967	241	49	1	1	NUM
cusj-10967	241	50	pdac	pdac	NOUN
cusj-10967	241	51	:	:	PUNCT
cusj-10967	241	52	pancreatic	pancreatic	ADJ
cusj-10967	241	53	ductal	ductal	ADJ
cusj-10967	241	54	adenocarcinoma	adenocarcinoma	PROPN
cusj-10967	241	55	cd19	cd19	PROPN
cusj-10967	241	56	:	:	PUNCT
cusj-10967	241	57	b	b	X
cusj-10967	241	58	-	-	PUNCT
cusj-10967	241	59	lymphocyte	lymphocyte	ADJ
cusj-10967	241	60	antigen	antigen	NOUN
cusj-10967	242	1	cd19	cd19	PROPN
cusj-10967	242	2	references	reference	NOUN
cusj-10967	242	3	[	[	X
cusj-10967	242	4	1	1	NUM
cusj-10967	242	5	]	]	PUNCT
cusj-10967	242	6	o.	o.	NOUN
cusj-10967	242	7	hemminki	hemminki	PROPN
cusj-10967	242	8	,	,	PUNCT
cusj-10967	242	9	j.	j.	PROPN
cusj-10967	242	10	m.	m.	PROPN
cusj-10967	242	11	dos	dos	PROPN
cusj-10967	242	12	santos	santos	PROPN
cusj-10967	242	13	,	,	PUNCT
cusj-10967	242	14	a.	a.	NOUN
cusj-10967	242	15	hemminki	hemminki	NOUN
cusj-10967	242	16	,	,	PUNCT
cusj-10967	242	17	oncolytic	oncolytic	ADJ
cusj-10967	242	18	viruses	virus	NOUN
cusj-10967	242	19	for	for	ADP
cusj-10967	242	20	cancer	cancer	NOUN
cusj-10967	242	21	immunotherapy	immunotherapy	NOUN
cusj-10967	242	22	.	.	PUNCT
cusj-10967	243	1	j	j	PROPN
cusj-10967	243	2	hematol	hematol	PROPN
cusj-10967	243	3	oncol	oncol	ADJ
cusj-10967	243	4	13	13	NUM
cusj-10967	243	5	,	,	PUNCT
cusj-10967	243	6	84	84	NUM
cusj-10967	243	7	(	(	PUNCT
cusj-10967	243	8	2020	2020	NUM
cusj-10967	243	9	)	)	PUNCT
cusj-10967	243	10	.	.	PUNCT
cusj-10967	244	1	[	[	X
cusj-10967	244	2	2	2	X
cusj-10967	244	3	]	]	PUNCT
cusj-10967	244	4	p.	p.	NOUN
cusj-10967	244	5	k.	k.	PROPN
cusj-10967	245	1	bommareddy	bommareddy	PROPN
cusj-10967	245	2	,	,	PUNCT
cusj-10967	245	3	m.	m.	NOUN
cusj-10967	245	4	shettigar	shettigar	NOUN
cusj-10967	245	5	,	,	PUNCT
cusj-10967	245	6	h.	h.	PROPN
cusj-10967	245	7	l.	l.	PROPN
cusj-10967	245	8	kaufman	kaufman	PROPN
cusj-10967	245	9	,	,	PUNCT
cusj-10967	245	10	integrating	integrate	VERB
cusj-10967	245	11	oncolytic	oncolytic	ADJ
cusj-10967	245	12	viruses	virus	NOUN
cusj-10967	245	13	in	in	ADP
cusj-10967	245	14	combination	combination	NOUN
cusj-10967	245	15	cancer	cancer	NOUN
cusj-10967	245	16	immunotherapy	immunotherapy	NOUN
cusj-10967	245	17	.	.	PUNCT
cusj-10967	246	1	nat	nat	PROPN
cusj-10967	246	2	rev	rev	VERB
cusj-10967	246	3	immunol	immunol	PROPN
cusj-10967	246	4	18	18	NUM
cusj-10967	246	5	,	,	PUNCT
cusj-10967	246	6	498	498	NUM
cusj-10967	246	7	-	-	SYM
cusj-10967	246	8	513	513	NUM
cusj-10967	246	9	(	(	PUNCT
cusj-10967	246	10	2018	2018	NUM
cusj-10967	246	11	)	)	PUNCT
cusj-10967	246	12	.	.	PUNCT
cusj-10967	247	1	[	[	X
cusj-10967	247	2	3	3	X
cusj-10967	247	3	]	]	X
cusj-10967	247	4	e.	e.	PROPN
cusj-10967	247	5	ylosmaki	ylosmaki	PROPN
cusj-10967	247	6	,	,	PUNCT
cusj-10967	247	7	v.	v.	CCONJ
cusj-10967	247	8	cerullo	cerullo	PROPN
cusj-10967	247	9	,	,	PUNCT
cusj-10967	247	10	design	design	NOUN
cusj-10967	247	11	and	and	CCONJ
cusj-10967	247	12	application	application	NOUN
cusj-10967	247	13	of	of	ADP
cusj-10967	247	14	oncolytic	oncolytic	ADJ
cusj-10967	247	15	viruses	virus	NOUN
cusj-10967	247	16	for	for	ADP
cusj-10967	247	17	cancer	cancer	NOUN
cusj-10967	247	18	immunotherapy	immunotherapy	NOUN
cusj-10967	247	19	.	.	PUNCT
cusj-10967	248	1	curr	curr	PROPN
cusj-10967	248	2	opin	opin	PROPN
cusj-10967	248	3	biotechnol	biotechnol	NOUN
cusj-10967	248	4	65	65	NUM
cusj-10967	248	5	,	,	PUNCT
cusj-10967	248	6	25	25	NUM
cusj-10967	248	7	-	-	SYM
cusj-10967	248	8	36	36	NUM
cusj-10967	248	9	(	(	PUNCT
cusj-10967	248	10	2020	2020	NUM
cusj-10967	248	11	)	)	PUNCT
cusj-10967	248	12	.	.	PUNCT
cusj-10967	249	1	[	[	X
cusj-10967	249	2	4	4	X
cusj-10967	249	3	]	]	X
cusj-10967	249	4	e.	e.	PROPN
cusj-10967	249	5	ramelyte	ramelyte	PROPN
cusj-10967	249	6	et	et	PROPN
cusj-10967	249	7	al	al	PROPN
cusj-10967	249	8	.	.	PROPN
cusj-10967	249	9	,	,	PUNCT
cusj-10967	249	10	oncolytic	oncolytic	PROPN
cusj-10967	249	11	virotherapymediated	virotherapymediate	VERB
cusj-10967	249	12	anti	anti	ADJ
cusj-10967	249	13	-	-	ADJ
cusj-10967	249	14	tumor	tumor	ADJ
cusj-10967	249	15	response	response	NOUN
cusj-10967	249	16	:	:	PUNCT
cusj-10967	249	17	a	a	DET
cusj-10967	249	18	singlecell	singlecell	NOUN
cusj-10967	249	19	perspective	perspective	NOUN
cusj-10967	249	20	.	.	PUNCT
cusj-10967	250	1	cancer	cancer	NOUN
cusj-10967	250	2	cell	cell	NOUN
cusj-10967	250	3	39	39	NUM
cusj-10967	250	4	,	,	PUNCT
cusj-10967	250	5	394406	394406	NUM
cusj-10967	250	6	e394	e394	PROPN
cusj-10967	250	7	(	(	PUNCT
cusj-10967	250	8	2021	2021	NUM
cusj-10967	250	9	)	)	PUNCT
cusj-10967	250	10	.	.	PUNCT
cusj-10967	251	1	[	[	X
cusj-10967	251	2	5	5	X
cusj-10967	251	3	]	]	PUNCT
cusj-10967	251	4	v.	v.	ADP
cusj-10967	251	5	cervera	cervera	NOUN
cusj-10967	251	6	-	-	PUNCT
cusj-10967	251	7	carrascon	carrascon	NOUN
cusj-10967	251	8	et	et	PROPN
cusj-10967	251	9	al	al	PROPN
cusj-10967	251	10	.	.	PROPN
cusj-10967	251	11	,	,	PUNCT
cusj-10967	251	12	tumor	tumor	NOUN
cusj-10967	251	13	microenvironment	microenvironment	NOUN
cusj-10967	251	14	remodeling	remodeling	NOUN
cusj-10967	251	15	by	by	ADP
cusj-10967	251	16	an	an	DET
cusj-10967	251	17	engineered	engineer	VERB
cusj-10967	251	18	oncolytic	oncolytic	ADJ
cusj-10967	251	19	adenovirus	adenovirus	NOUN
cusj-10967	251	20	results	result	NOUN
cusj-10967	251	21	in	in	ADP
cusj-10967	251	22	improved	improved	ADJ
cusj-10967	251	23	outcome	outcome	NOUN
cusj-10967	251	24	from	from	ADP
cusj-10967	251	25	pd	pd	PROPN
cusj-10967	251	26	-	-	PUNCT
cusj-10967	251	27	l1	l1	PROPN
cusj-10967	251	28	inhibition	inhibition	NOUN
cusj-10967	251	29	.	.	PUNCT
cusj-10967	252	1	oncoimmunology	oncoimmunology	NOUN
cusj-10967	252	2	9	9	NUM
cusj-10967	252	3	,	,	PUNCT
cusj-10967	252	4	1761229	1761229	NUM
cusj-10967	252	5	(	(	PUNCT
cusj-10967	252	6	2020	2020	NUM
cusj-10967	252	7	)	)	PUNCT
cusj-10967	252	8	.	.	PUNCT
cusj-10967	253	1	[	[	X
cusj-10967	253	2	6	6	NUM
cusj-10967	253	3	]	]	PUNCT
cusj-10967	253	4	c.	c.	PROPN
cusj-10967	253	5	lin	lin	PROPN
cusj-10967	253	6	et	et	PROPN
cusj-10967	253	7	al	al	PROPN
cusj-10967	253	8	.	.	PROPN
cusj-10967	253	9	,	,	PUNCT
cusj-10967	253	10	intratumoral	intratumoral	ADJ
cusj-10967	253	11	delivery	delivery	NOUN
cusj-10967	253	12	of	of	ADP
cusj-10967	253	13	a	a	DET
cusj-10967	253	14	pd-1	pd-1	ADV
cusj-10967	253	15	-	-	PUNCT
cusj-10967	253	16	blocking	block	VERB
cusj-10967	253	17	scfv	scfv	NOUN
cusj-10967	253	18	encoded	encode	VERB
cusj-10967	253	19	in	in	ADP
cusj-10967	253	20	oncolytic	oncolytic	ADJ
cusj-10967	253	21	hsv-1	hsv-1	X
cusj-10967	253	22	promotes	promote	VERB
cusj-10967	253	23	antitumor	antitumor	PROPN
cusj-10967	253	24	immunity	immunity	NOUN
cusj-10967	253	25	and	and	CCONJ
cusj-10967	253	26	synergizes	synergize	VERB
cusj-10967	253	27	with	with	ADP
cusj-10967	253	28	tigit	tigit	NOUN
cusj-10967	253	29	blockade	blockade	NOUN
cusj-10967	253	30	.	.	PUNCT
cusj-10967	254	1	cancer	cancer	NOUN
cusj-10967	254	2	immunol	immunol	NOUN
cusj-10967	254	3	res	re	NOUN
cusj-10967	254	4	8	8	NUM
cusj-10967	254	5	,	,	PUNCT
cusj-10967	254	6	632647	632647	NUM
cusj-10967	254	7	(	(	PUNCT
cusj-10967	254	8	2020	2020	NUM
cusj-10967	254	9	)	)	PUNCT
cusj-10967	254	10	.	.	PUNCT
cusj-10967	255	1	[	[	X
cusj-10967	255	2	7	7	X
cusj-10967	255	3	]	]	X
cusj-10967	255	4	c.	c.	NOUN
cusj-10967	255	5	gentile	gentile	NOUN
cusj-10967	255	6	et	et	PROPN
cusj-10967	255	7	al	al	PROPN
cusj-10967	255	8	.	.	PROPN
cusj-10967	255	9	,	,	PUNCT
cusj-10967	255	10	generation	generation	NOUN
cusj-10967	255	11	of	of	ADP
cusj-10967	255	12	a	a	DET
cusj-10967	255	13	retargeted	retargete	VERB
cusj-10967	255	14	oncolytic	oncolytic	ADJ
cusj-10967	255	15	herpes	herpe	NOUN
cusj-10967	255	16	virus	virus	NOUN
cusj-10967	255	17	encoding	encode	VERB
cusj-10967	255	18	adenosine	adenosine	NOUN
cusj-10967	255	19	deaminase	deaminase	NOUN
cusj-10967	255	20	for	for	ADP
cusj-10967	255	21	tumor	tumor	NOUN
cusj-10967	255	22	adenosine	adenosine	NOUN
cusj-10967	255	23	clearance	clearance	NOUN
cusj-10967	255	24	.	.	PUNCT
cusj-10967	256	1	int	int	PROPN
cusj-10967	256	2	j	j	PROPN
cusj-10967	256	3	mol	mol	ADP
cusj-10967	256	4	sci	sci	PROPN
cusj-10967	256	5	22	22	NUM
cusj-10967	256	6	,	,	PUNCT
cusj-10967	256	7	(	(	PUNCT
cusj-10967	256	8	2021	2021	NUM
cusj-10967	256	9	)	)	PUNCT
cusj-10967	256	10	.	.	PUNCT
cusj-10967	257	1	[	[	X
cusj-10967	257	2	8	8	NUM
cusj-10967	257	3	]	]	PUNCT
cusj-10967	257	4	m.	m.	NOUN
cusj-10967	257	5	keshavarz	keshavarz	PROPN
cusj-10967	257	6	et	et	PROPN
cusj-10967	257	7	al	al	PROPN
cusj-10967	257	8	.	.	PROPN
cusj-10967	257	9	,	,	PUNCT
cusj-10967	257	10	oncolytic	oncolytic	ADJ
cusj-10967	257	11	newcastle	newcastle	PROPN
cusj-10967	257	12	disease	disease	PROPN
cusj-10967	257	13	virus	virus	NOUN
cusj-10967	257	14	delivered	deliver	VERB
cusj-10967	257	15	by	by	ADP
cusj-10967	257	16	mesenchymal	mesenchymal	ADJ
cusj-10967	257	17	stem	stem	NOUN
cusj-10967	257	18	cells	cell	NOUN
cusj-10967	257	19	-	-	PUNCT
cusj-10967	257	20	engineered	engineer	VERB
cusj-10967	257	21	system	system	NOUN
cusj-10967	257	22	enhances	enhance	VERB
cusj-10967	257	23	the	the	DET
cusj-10967	257	24	therapeutic	therapeutic	ADJ
cusj-10967	257	25	effects	effect	NOUN
cusj-10967	257	26	altering	alter	VERB
cusj-10967	257	27	tumor	tumor	NOUN
cusj-10967	257	28	microenvironment	microenvironment	NOUN
cusj-10967	257	29	.	.	PUNCT
cusj-10967	258	1	virol	virol	PROPN
cusj-10967	258	2	j	j	PROPN
cusj-10967	258	3	17	17	NUM
cusj-10967	258	4	,	,	PUNCT
cusj-10967	258	5	64	64	NUM
cusj-10967	258	6	(	(	PUNCT
cusj-10967	258	7	2020	2020	NUM
cusj-10967	258	8	)	)	PUNCT
cusj-10967	258	9	.	.	PUNCT
cusj-10967	259	1	[	[	X
cusj-10967	259	2	9	9	NUM
cusj-10967	259	3	]	]	X
cusj-10967	259	4	b.	b.	PROPN
cusj-10967	259	5	b.	b.	PROPN
cusj-10967	259	6	haines	haines	PROPN
cusj-10967	259	7	et	et	PROPN
cusj-10967	259	8	al	al	PROPN
cusj-10967	259	9	.	.	PROPN
cusj-10967	259	10	,	,	PUNCT
cusj-10967	259	11	oncr-177	oncr-177	ADJ
cusj-10967	259	12	,	,	PUNCT
cusj-10967	259	13	an	an	DET
cusj-10967	259	14	oncolytic	oncolytic	NOUN
cusj-10967	259	15	hsv-1	hsv-1	NOUN
cusj-10967	259	16	designed	design	VERB
cusj-10967	259	17	to	to	PART
cusj-10967	259	18	potently	potently	ADV
cusj-10967	259	19	activate	activate	VERB
cusj-10967	259	20	systemic	systemic	ADJ
cusj-10967	259	21	antitumor	antitumor	PROPN
cusj-10967	259	22	immunity	immunity	NOUN
cusj-10967	259	23	.	.	PUNCT
cusj-10967	260	1	cancer	cancer	NOUN
cusj-10967	260	2	immunol	immunol	NOUN
cusj-10967	260	3	res	re	NOUN
cusj-10967	260	4	9	9	NUM
cusj-10967	260	5	,	,	PUNCT
cusj-10967	260	6	291	291	NUM
cusj-10967	260	7	-	-	SYM
cusj-10967	260	8	308	308	NUM
cusj-10967	260	9	(	(	PUNCT
cusj-10967	260	10	2021	2021	NUM
cusj-10967	260	11	)	)	PUNCT
cusj-10967	260	12	.	.	PUNCT
cusj-10967	261	1	[	[	X
cusj-10967	261	2	10	10	NUM
cusj-10967	261	3	]	]	X
cusj-10967	261	4	n.	n.	PROPN
cusj-10967	261	5	kurisu	kurisu	PROPN
cusj-10967	261	6	et	et	PROPN
cusj-10967	261	7	al	al	PROPN
cusj-10967	261	8	.	.	PROPN
cusj-10967	261	9	,	,	PUNCT
cusj-10967	261	10	oncolytic	oncolytic	VERB
cusj-10967	261	11	reovirusmediated	reovirusmediated	ADJ
cusj-10967	261	12	killing	killing	NOUN
cusj-10967	261	13	of	of	ADP
cusj-10967	261	14	mouse	mouse	NOUN
cusj-10967	261	15	cancerassociated	cancerassociate	VERB
cusj-10967	261	16	fibroblasts	fibroblast	NOUN
cusj-10967	261	17	.	.	PUNCT
cusj-10967	262	1	int	int	NOUN
cusj-10967	262	2	j	j	PROPN
cusj-10967	262	3	pharm	pharm	PROPN
cusj-10967	262	4	610	610	NUM
cusj-10967	262	5	,	,	PUNCT
cusj-10967	262	6	121269	121269	NUM
cusj-10967	262	7	(	(	PUNCT
cusj-10967	262	8	2021	2021	NUM
cusj-10967	262	9	)	)	PUNCT
cusj-10967	262	10	.	.	PUNCT
cusj-10967	263	1	[	[	X
cusj-10967	263	2	11	11	NUM
cusj-10967	263	3	]	]	X
cusj-10967	263	4	y.	y.	PROPN
cusj-10967	263	5	j.	j.	PROPN
cusj-10967	263	6	hwang	hwang	PROPN
cusj-10967	263	7	,	,	PUNCT
cusj-10967	263	8	h.	h.	PROPN
cusj-10967	263	9	myung	myung	PROPN
cusj-10967	263	10	,	,	PUNCT
cusj-10967	263	11	engineered	engineer	VERB
cusj-10967	263	12	bacteriophage	bacteriophage	NOUN
cusj-10967	263	13	t7	t7	PROPN
cusj-10967	263	14	as	as	ADP
cusj-10967	263	15	a	a	DET
cusj-10967	263	16	potent	potent	ADJ
cusj-10967	263	17	anticancer	anticancer	NOUN
cusj-10967	263	18	agent	agent	NOUN
cusj-10967	263	19	in	in	ADP
cusj-10967	263	20	vivo	vivo	NOUN
cusj-10967	263	21	.	.	PUNCT
cusj-10967	264	1	front	front	ADJ
cusj-10967	264	2	microbiol	microbiol	PROPN
cusj-10967	264	3	11	11	NUM
cusj-10967	264	4	,	,	PUNCT
cusj-10967	264	5	491001	491001	NUM
cusj-10967	264	6	(	(	PUNCT
cusj-10967	264	7	2020	2020	NUM
cusj-10967	264	8	)	)	PUNCT
cusj-10967	264	9	.	.	PUNCT
cusj-10967	265	1	[	[	X
cusj-10967	265	2	12	12	NUM
cusj-10967	265	3	]	]	X
cusj-10967	265	4	s.	s.	PROPN
cusj-10967	265	5	chaurasiya	chaurasiya	PROPN
cusj-10967	265	6	,	,	PUNCT
cusj-10967	265	7	y.	y.	PROPN
cusj-10967	265	8	fong	fong	PROPN
cusj-10967	265	9	,	,	PUNCT
cusj-10967	265	10	s.	s.	PROPN
cusj-10967	265	11	g.	g.	PROPN
cusj-10967	265	12	warner	warner	PROPN
cusj-10967	265	13	,	,	PUNCT
cusj-10967	265	14	oncolytic	oncolytic	ADJ
cusj-10967	265	15	virotherapy	virotherapy	NOUN
cusj-10967	265	16	for	for	ADP
cusj-10967	265	17	cancer	cancer	NOUN
cusj-10967	265	18	:	:	PUNCT
cusj-10967	265	19	clinical	clinical	ADJ
cusj-10967	265	20	experience	experience	NOUN
cusj-10967	265	21	.	.	PUNCT
cusj-10967	266	1	biomedicines	biomedicine	VERB
cusj-10967	266	2	9	9	NUM
cusj-10967	266	3	,	,	PUNCT
cusj-10967	266	4	(	(	PUNCT
cusj-10967	266	5	2021	2021	NUM
cusj-10967	266	6	)	)	PUNCT
cusj-10967	266	7	.	.	PUNCT
cusj-10967	267	1	[	[	X
cusj-10967	267	2	13	13	NUM
cusj-10967	267	3	]	]	PUNCT
cusj-10967	267	4	z.	z.	PROPN
cusj-10967	267	5	wang	wang	PROPN
cusj-10967	267	6	et	et	PROPN
cusj-10967	267	7	al	al	PROPN
cusj-10967	267	8	.	.	PROPN
cusj-10967	267	9	,	,	PUNCT
cusj-10967	267	10	enhancing	enhance	VERB
cusj-10967	267	11	the	the	DET
cusj-10967	267	12	antitumor	antitumor	PROPN
cusj-10967	267	13	activity	activity	NOUN
cusj-10967	267	14	of	of	ADP
cusj-10967	267	15	an	an	DET
cusj-10967	267	16	engineered	engineer	VERB
cusj-10967	267	17	trail	trail	NOUN
cusj-10967	267	18	-	-	PUNCT
cusj-10967	267	19	coated	coat	VERB
cusj-10967	267	20	oncolytic	oncolytic	ADJ
cusj-10967	267	21	adenovirus	adenovirus	NOUN
cusj-10967	267	22	for	for	ADP
cusj-10967	267	23	treating	treat	VERB
cusj-10967	267	24	acute	acute	ADJ
cusj-10967	267	25	myeloid	myeloid	ADJ
cusj-10967	267	26	leukemia	leukemia	NOUN
cusj-10967	267	27	.	.	PUNCT
cusj-10967	268	1	signal	signal	PROPN
cusj-10967	268	2	transduct	transduct	NOUN
cusj-10967	268	3	target	target	NOUN
cusj-10967	268	4	ther	ther	ADV
cusj-10967	268	5	5	5	NUM
cusj-10967	268	6	,	,	PUNCT
cusj-10967	268	7	40	40	NUM
cusj-10967	268	8	(	(	PUNCT
cusj-10967	268	9	2020	2020	NUM
cusj-10967	268	10	)	)	PUNCT
cusj-10967	268	11	.	.	PUNCT
cusj-10967	269	1	[	[	X
cusj-10967	269	2	14	14	NUM
cusj-10967	269	3	]	]	X
cusj-10967	269	4	l.	l.	PROPN
cusj-10967	269	5	menotti	menotti	PROPN
cusj-10967	269	6	et	et	PROPN
cusj-10967	269	7	al	al	PROPN
cusj-10967	269	8	.	.	PROPN
cusj-10967	269	9	,	,	PUNCT
cusj-10967	269	10	hsv	hsv	PROPN
cusj-10967	269	11	as	as	ADP
cusj-10967	269	12	a	a	DET
cusj-10967	269	13	platform	platform	NOUN
cusj-10967	269	14	for	for	ADP
cusj-10967	269	15	the	the	DET
cusj-10967	269	16	generation	generation	NOUN
cusj-10967	269	17	of	of	ADP
cusj-10967	269	18	retargeted	retargete	VERB
cusj-10967	269	19	,	,	PUNCT
cusj-10967	269	20	armed	armed	ADJ
cusj-10967	269	21	,	,	PUNCT
cusj-10967	269	22	and	and	CCONJ
cusj-10967	269	23	reporter	reporter	NOUN
cusj-10967	269	24	-	-	PUNCT
cusj-10967	269	25	expressing	express	VERB
cusj-10967	269	26	oncolytic	oncolytic	ADJ
cusj-10967	269	27	viruses	virus	NOUN
cusj-10967	269	28	.	.	PUNCT
cusj-10967	270	1	viruses	virus	NOUN
cusj-10967	270	2	10	10	NUM
cusj-10967	270	3	,	,	PUNCT
cusj-10967	270	4	(	(	PUNCT
cusj-10967	270	5	2018	2018	NUM
cusj-10967	270	6	)	)	PUNCT
cusj-10967	270	7	.	.	PUNCT
cusj-10967	271	1	[	[	X
cusj-10967	271	2	15	15	NUM
cusj-10967	271	3	]	]	PUNCT
cusj-10967	271	4	k.	k.	PROPN
cusj-10967	271	5	j.	j.	PROPN
cusj-10967	271	6	kim	kim	PROPN
cusj-10967	271	7	et	et	PROPN
cusj-10967	271	8	al	al	PROPN
cusj-10967	271	9	.	.	PROPN
cusj-10967	271	10	,	,	PUNCT
cusj-10967	271	11	antitumor	antitumor	PROPN
cusj-10967	271	12	effects	effect	NOUN
cusj-10967	271	13	of	of	ADP
cusj-10967	271	14	il12	il12	PROPN
cusj-10967	271	15	and	and	CCONJ
cusj-10967	271	16	gm	gm	PROPN
cusj-10967	271	17	-	-	PUNCT
cusj-10967	271	18	csf	csf	NOUN
cusj-10967	271	19	co	co	VERB
cusj-10967	271	20	-	-	VERB
cusj-10967	271	21	expressed	express	VERB
cusj-10967	271	22	in	in	ADP
cusj-10967	271	23	an	an	DET
cusj-10967	271	24	engineered	engineer	VERB
cusj-10967	271	25	oncolytic	oncolytic	NOUN
cusj-10967	271	26	hsv-1	hsv-1	NOUN
cusj-10967	271	27	.	.	PUNCT
cusj-10967	272	1	gene	gene	NOUN
cusj-10967	272	2	ther	ther	ADV
cusj-10967	272	3	28	28	NUM
cusj-10967	272	4	,	,	PUNCT
cusj-10967	272	5	186	186	NUM
cusj-10967	272	6	-	-	SYM
cusj-10967	272	7	198	198	NUM
cusj-10967	272	8	(	(	PUNCT
cusj-10967	272	9	2021	2021	NUM
cusj-10967	272	10	)	)	PUNCT
cusj-10967	272	11	.	.	PUNCT
cusj-10967	273	1	[	[	X
cusj-10967	273	2	16	16	NUM
cusj-10967	273	3	]	]	X
cusj-10967	273	4	d.	d.	PROPN
cusj-10967	273	5	b.	b.	PROPN
cusj-10967	274	1	rivadeneira	rivadeneira	PROPN
cusj-10967	274	2	et	et	PROPN
cusj-10967	274	3	al	al	PROPN
cusj-10967	274	4	.	.	PROPN
cusj-10967	274	5	,	,	PUNCT
cusj-10967	274	6	oncolytic	oncolytic	ADJ
cusj-10967	274	7	viruses	virus	NOUN
cusj-10967	274	8	engineered	engineer	VERB
cusj-10967	274	9	to	to	PART
cusj-10967	274	10	enforce	enforce	VERB
cusj-10967	274	11	leptin	leptin	NOUN
cusj-10967	274	12	expression	expression	NOUN
cusj-10967	274	13	reprogram	reprogram	NOUN
cusj-10967	274	14	tumor	tumor	NOUN
cusj-10967	274	15	-	-	PUNCT
cusj-10967	274	16	infiltrating	infiltrate	VERB
cusj-10967	274	17	t	t	NOUN
cusj-10967	274	18	cell	cell	NOUN
cusj-10967	274	19	metabolism	metabolism	NOUN
cusj-10967	274	20	and	and	CCONJ
cusj-10967	274	21	promote	promote	VERB
cusj-10967	274	22	tumor	tumor	NOUN
cusj-10967	274	23	clearance	clearance	NOUN
cusj-10967	274	24	.	.	PUNCT
cusj-10967	275	1	immunity	immunity	NOUN
cusj-10967	275	2	51	51	NUM
cusj-10967	275	3	,	,	PUNCT
cusj-10967	275	4	548	548	NUM
cusj-10967	275	5	-	-	SYM
cusj-10967	275	6	560	560	NUM
cusj-10967	275	7	e544	e544	PROPN
cusj-10967	275	8	(	(	PUNCT
cusj-10967	275	9	2019	2019	NUM
cusj-10967	275	10	)	)	PUNCT
cusj-10967	275	11	.	.	PUNCT
cusj-10967	276	1	[	[	X
cusj-10967	276	2	17	17	NUM
cusj-10967	276	3	]	]	PUNCT
cusj-10967	276	4	s.	s.	PROPN
cusj-10967	276	5	atasheva	atasheva	PROPN
cusj-10967	276	6	et	et	PROPN
cusj-10967	276	7	al	al	PROPN
cusj-10967	276	8	.	.	PROPN
cusj-10967	276	9	,	,	PUNCT
cusj-10967	276	10	systemic	systemic	ADJ
cusj-10967	276	11	cancer	cancer	NOUN
cusj-10967	276	12	therapy	therapy	NOUN
cusj-10967	276	13	with	with	ADP
cusj-10967	276	14	engineered	engineer	VERB
cusj-10967	276	15	adenovirus	adenovirus	NOUN
cusj-10967	276	16	that	that	PRON
cusj-10967	276	17	evades	evade	VERB
cusj-10967	276	18	innate	innate	ADJ
cusj-10967	276	19	immunity	immunity	NOUN
cusj-10967	276	20	.	.	PUNCT
cusj-10967	277	1	sci	sci	PROPN
cusj-10967	277	2	transl	transl	PROPN
cusj-10967	277	3	med	med	PROPN
cusj-10967	277	4	12	12	NUM
cusj-10967	277	5	,	,	PUNCT
cusj-10967	277	6	(	(	PUNCT
cusj-10967	277	7	2020	2020	NUM
cusj-10967	277	8	)	)	PUNCT
cusj-10967	277	9	.	.	PUNCT
cusj-10967	278	1	columbia	columbia	PROPN
cusj-10967	278	2	undergraduate	undergraduate	PROPN
cusj-10967	278	3	science	science	PROPN
cusj-10967	278	4	journal	journal	PROPN
cusj-10967	278	5	vol	vol	NOUN
cusj-10967	278	6	.	.	PROPN
cusj-10967	278	7	18	18	NUM
cusj-10967	278	8	,	,	PUNCT
cusj-10967	278	9	2024	2024	NUM
cusj-10967	278	10	manjila	manjila	NOUN
cusj-10967	279	1	[	[	X
cusj-10967	279	2	18	18	NUM
cusj-10967	279	3	]	]	X
cusj-10967	279	4	e.	e.	PROPN
cusj-10967	279	5	s.	s.	PROPN
cusj-10967	279	6	bah	bah	PROPN
cusj-10967	279	7	,	,	PUNCT
cusj-10967	279	8	r.	r.	PROPN
cusj-10967	279	9	a.	a.	PROPN
cusj-10967	279	10	nace	nace	PROPN
cusj-10967	279	11	,	,	PUNCT
cusj-10967	279	12	k.	k.	PROPN
cusj-10967	279	13	w.	w.	PROPN
cusj-10967	279	14	peng	peng	PROPN
cusj-10967	279	15	,	,	PUNCT
cusj-10967	279	16	m.	m.	PROPN
cusj-10967	279	17	a.	a.	PROPN
cusj-10967	279	18	munoz	munoz	PROPN
cusj-10967	279	19	-	-	PUNCT
cusj-10967	279	20	alia	alia	PROPN
cusj-10967	279	21	,	,	PUNCT
cusj-10967	279	22	s.	s.	PROPN
cusj-10967	279	23	j.	j.	PROPN
cusj-10967	279	24	russell	russell	PROPN
cusj-10967	279	25	,	,	PUNCT
cusj-10967	279	26	retargeted	retargete	VERB
cusj-10967	279	27	and	and	CCONJ
cusj-10967	279	28	stealth	stealth	NOUN
cusj-10967	279	29	-	-	PUNCT
cusj-10967	279	30	modified	modify	VERB
cusj-10967	279	31	oncolytic	oncolytic	ADJ
cusj-10967	279	32	measles	measle	NOUN
cusj-10967	279	33	viruses	virus	NOUN
cusj-10967	279	34	for	for	ADP
cusj-10967	279	35	systemic	systemic	ADJ
cusj-10967	279	36	cancer	cancer	NOUN
cusj-10967	279	37	therapy	therapy	NOUN
cusj-10967	279	38	in	in	ADP
cusj-10967	279	39	measles	measle	NOUN
cusj-10967	279	40	immune	immune	ADJ
cusj-10967	279	41	patients	patient	NOUN
cusj-10967	279	42	.	.	PUNCT
cusj-10967	280	1	mol	mol	ADP
cusj-10967	280	2	cancer	cancer	NOUN
cusj-10967	280	3	ther	ther	PROPN
cusj-10967	280	4	19	19	NUM
cusj-10967	280	5	,	,	PUNCT
cusj-10967	280	6	2057	2057	NUM
cusj-10967	280	7	-	-	SYM
cusj-10967	280	8	2067	2067	NUM
cusj-10967	280	9	(	(	PUNCT
cusj-10967	280	10	2020	2020	NUM
cusj-10967	280	11	)	)	PUNCT
cusj-10967	280	12	.	.	PUNCT
cusj-10967	281	1	[	[	X
cusj-10967	281	2	19	19	NUM
cusj-10967	281	3	]	]	PUNCT
cusj-10967	281	4	b.	b.	PROPN
cusj-10967	281	5	zhang	zhang	PROPN
cusj-10967	281	6	et	et	PROPN
cusj-10967	281	7	al	al	PROPN
cusj-10967	281	8	.	.	PROPN
cusj-10967	281	9	,	,	PUNCT
cusj-10967	281	10	intratumoral	intratumoral	PROPN
cusj-10967	281	11	oh2	oh2	PROPN
cusj-10967	281	12	,	,	PUNCT
cusj-10967	281	13	an	an	DET
cusj-10967	281	14	oncolytic	oncolytic	ADJ
cusj-10967	281	15	herpes	herpe	NOUN
cusj-10967	281	16	simplex	simplex	NOUN
cusj-10967	281	17	virus	virus	NOUN
cusj-10967	281	18	2	2	NUM
cusj-10967	281	19	,	,	PUNCT
cusj-10967	281	20	in	in	ADP
cusj-10967	281	21	patients	patient	NOUN
cusj-10967	281	22	with	with	ADP
cusj-10967	281	23	advanced	advanced	ADJ
cusj-10967	281	24	solid	solid	ADJ
cusj-10967	281	25	tumors	tumor	NOUN
cusj-10967	281	26	:	:	PUNCT
cusj-10967	281	27	a	a	DET
cusj-10967	281	28	multicenter	multicenter	NOUN
cusj-10967	281	29	,	,	PUNCT
cusj-10967	281	30	phase	phase	NOUN
cusj-10967	281	31	i	i	PROPN
cusj-10967	281	32	/	/	SYM
cusj-10967	281	33	ii	ii	PROPN
cusj-10967	281	34	clinical	clinical	ADJ
cusj-10967	281	35	trial	trial	NOUN
cusj-10967	281	36	.	.	PUNCT
cusj-10967	282	1	j	j	PROPN
cusj-10967	282	2	immunother	immunother	ADJ
cusj-10967	282	3	cancer	cancer	NOUN
cusj-10967	282	4	9	9	NUM
cusj-10967	282	5	,	,	PUNCT
cusj-10967	282	6	(	(	PUNCT
cusj-10967	282	7	2021	2021	NUM
cusj-10967	282	8	)	)	PUNCT
cusj-10967	282	9	.	.	PUNCT
cusj-10967	283	1	[	[	X
cusj-10967	283	2	20	20	NUM
cusj-10967	283	3	]	]	X
cusj-10967	283	4	j.	j.	PROPN
cusj-10967	283	5	fares	fares	PROPN
cusj-10967	283	6	et	et	PROPN
cusj-10967	283	7	al	al	PROPN
cusj-10967	283	8	.	.	PROPN
cusj-10967	283	9	,	,	PUNCT
cusj-10967	283	10	neural	neural	ADJ
cusj-10967	283	11	stem	stem	NOUN
cusj-10967	283	12	cell	cell	NOUN
cusj-10967	283	13	delivery	delivery	NOUN
cusj-10967	283	14	of	of	ADP
cusj-10967	283	15	an	an	DET
cusj-10967	283	16	oncolytic	oncolytic	ADJ
cusj-10967	283	17	adenovirus	adenovirus	NOUN
cusj-10967	283	18	in	in	ADP
cusj-10967	283	19	newly	newly	ADV
cusj-10967	283	20	diagnosed	diagnose	VERB
cusj-10967	283	21	malignant	malignant	ADJ
cusj-10967	283	22	glioma	glioma	NOUN
cusj-10967	283	23	:	:	PUNCT
cusj-10967	283	24	a	a	DET
cusj-10967	283	25	first	first	ADJ
cusj-10967	283	26	-	-	PUNCT
cusj-10967	283	27	in	in	ADP
cusj-10967	283	28	-	-	PUNCT
cusj-10967	283	29	human	human	ADJ
cusj-10967	283	30	,	,	PUNCT
cusj-10967	283	31	phase	phase	NOUN
cusj-10967	283	32	1	1	NUM
cusj-10967	283	33	,	,	PUNCT
cusj-10967	283	34	dose	dose	NOUN
cusj-10967	283	35	-	-	PUNCT
cusj-10967	283	36	escalation	escalation	NOUN
cusj-10967	283	37	trial	trial	NOUN
cusj-10967	283	38	.	.	PUNCT
cusj-10967	284	1	lancet	lancet	PROPN
cusj-10967	284	2	oncol	oncol	ADJ
cusj-10967	284	3	22	22	NUM
cusj-10967	284	4	,	,	PUNCT
cusj-10967	284	5	1103	1103	NUM
cusj-10967	284	6	-	-	SYM
cusj-10967	284	7	1114	1114	NUM
cusj-10967	284	8	(	(	PUNCT
cusj-10967	284	9	2021	2021	NUM
cusj-10967	284	10	)	)	PUNCT
cusj-10967	284	11	.	.	PUNCT
cusj-10967	285	1	[	[	X
cusj-10967	285	2	21	21	NUM
cusj-10967	285	3	]	]	X
cusj-10967	285	4	m.	m.	NOUN
cusj-10967	285	5	mondal	mondal	PROPN
cusj-10967	285	6	,	,	PUNCT
cusj-10967	285	7	j.	j.	PROPN
cusj-10967	285	8	guo	guo	PROPN
cusj-10967	285	9	,	,	PUNCT
cusj-10967	285	10	p.	p.	NOUN
cusj-10967	285	11	he	he	PRON
cusj-10967	285	12	,	,	PUNCT
cusj-10967	285	13	d.	d.	PROPN
cusj-10967	285	14	zhou	zhou	PROPN
cusj-10967	285	15	,	,	PUNCT
cusj-10967	285	16	recent	recent	ADJ
cusj-10967	285	17	advances	advance	NOUN
cusj-10967	285	18	of	of	ADP
cusj-10967	285	19	oncolytic	oncolytic	ADJ
cusj-10967	285	20	virus	virus	NOUN
cusj-10967	285	21	in	in	ADP
cusj-10967	285	22	cancer	cancer	NOUN
cusj-10967	285	23	therapy	therapy	NOUN
cusj-10967	285	24	.	.	PUNCT
cusj-10967	286	1	hum	hum	PROPN
cusj-10967	286	2	vaccin	vaccin	PROPN
cusj-10967	286	3	immunother	immunother	PROPN
cusj-10967	286	4	16	16	NUM
cusj-10967	286	5	,	,	PUNCT
cusj-10967	286	6	2389	2389	NUM
cusj-10967	286	7	-	-	SYM
cusj-10967	286	8	2402	2402	NUM
cusj-10967	286	9	(	(	PUNCT
cusj-10967	286	10	2020	2020	NUM
cusj-10967	286	11	)	)	PUNCT
cusj-10967	286	12	.	.	PUNCT
cusj-10967	287	1	[	[	X
cusj-10967	287	2	22	22	NUM
cusj-10967	287	3	]	]	X
cusj-10967	287	4	h.	h.	PROPN
cusj-10967	287	5	fukuhara	fukuhara	PROPN
cusj-10967	287	6	,	,	PUNCT
cusj-10967	287	7	y.	y.	PROPN
cusj-10967	287	8	takeshima	takeshima	PROPN
cusj-10967	287	9	,	,	PUNCT
cusj-10967	287	10	t.	t.	NOUN
cusj-10967	287	11	todo	todo	NOUN
cusj-10967	287	12	,	,	PUNCT
cusj-10967	287	13	triple	triple	ADJ
cusj-10967	287	14	-	-	PUNCT
cusj-10967	287	15	mutated	mutate	VERB
cusj-10967	287	16	oncolytic	oncolytic	ADJ
cusj-10967	287	17	herpes	herpe	NOUN
cusj-10967	287	18	virus	virus	NOUN
cusj-10967	287	19	for	for	ADP
cusj-10967	287	20	treating	treat	VERB
cusj-10967	287	21	both	both	DET
cusj-10967	287	22	fastand	fastand	ADJ
cusj-10967	287	23	slow	slow	ADV
cusj-10967	287	24	-	-	PUNCT
cusj-10967	287	25	growing	grow	VERB
cusj-10967	287	26	tumors	tumor	NOUN
cusj-10967	287	27	.	.	PUNCT
cusj-10967	288	1	cancer	cancer	NOUN
cusj-10967	288	2	sci	sci	PROPN
cusj-10967	288	3	112	112	NUM
cusj-10967	288	4	,	,	PUNCT
cusj-10967	288	5	3293	3293	NUM
cusj-10967	288	6	-	-	SYM
cusj-10967	288	7	3301	3301	NUM
cusj-10967	288	8	(	(	PUNCT
cusj-10967	288	9	2021	2021	NUM
cusj-10967	288	10	)	)	PUNCT
cusj-10967	288	11	.	.	PUNCT
cusj-10967	289	1	[	[	X
cusj-10967	289	2	23	23	NUM
cusj-10967	289	3	]	]	X
cusj-10967	289	4	f.	f.	PROPN
cusj-10967	289	5	cao	cao	PROPN
cusj-10967	289	6	et	et	PROPN
cusj-10967	289	7	al	al	PROPN
cusj-10967	289	8	.	.	PROPN
cusj-10967	289	9	,	,	PUNCT
cusj-10967	289	10	engineering	engineering	NOUN
cusj-10967	289	11	oncolytic	oncolytic	ADJ
cusj-10967	289	12	vaccinia	vaccinia	NOUN
cusj-10967	289	13	virus	virus	NOUN
cusj-10967	289	14	to	to	PART
cusj-10967	289	15	redirect	redirect	VERB
cusj-10967	289	16	macrophages	macrophage	NOUN
cusj-10967	289	17	to	to	ADP
cusj-10967	289	18	tumor	tumor	NOUN
cusj-10967	289	19	cells	cell	NOUN
cusj-10967	289	20	.	.	PUNCT
cusj-10967	290	1	adv	adv	PROPN
cusj-10967	290	2	cell	cell	NOUN
cusj-10967	290	3	gene	gene	NOUN
cusj-10967	290	4	ther	ther	ADV
cusj-10967	290	5	4	4	NUM
cusj-10967	290	6	,	,	PUNCT
cusj-10967	290	7	(	(	PUNCT
cusj-10967	290	8	2021	2021	NUM
cusj-10967	290	9	)	)	PUNCT
cusj-10967	290	10	.	.	PUNCT
cusj-10967	291	1	[	[	X
cusj-10967	291	2	24	24	NUM
cusj-10967	291	3	]	]	PUNCT
cusj-10967	291	4	s.	s.	PROPN
cusj-10967	291	5	liu	liu	PROPN
cusj-10967	291	6	et	et	PROPN
cusj-10967	291	7	al	al	PROPN
cusj-10967	291	8	.	.	PROPN
cusj-10967	291	9	,	,	PUNCT
cusj-10967	291	10	antitumor	antitumor	PROPN
cusj-10967	291	11	efficacy	efficacy	NOUN
cusj-10967	291	12	of	of	ADP
cusj-10967	291	13	oncolytic	oncolytic	ADJ
cusj-10967	291	14	hsv-1	hsv-1	NOUN
cusj-10967	291	15	expressing	express	VERB
cusj-10967	291	16	cytosine	cytosine	NOUN
cusj-10967	291	17	deaminase	deaminase	NOUN
cusj-10967	291	18	is	be	AUX
cusj-10967	291	19	synergistically	synergistically	ADV
cusj-10967	291	20	enhanced	enhance	VERB
cusj-10967	291	21	by	by	ADP
cusj-10967	291	22	dpd	dpd	PROPN
cusj-10967	291	23	down	down	ADJ
cusj-10967	291	24	-	-	PUNCT
cusj-10967	291	25	regulation	regulation	NOUN
cusj-10967	291	26	and	and	CCONJ
cusj-10967	291	27	emt	emt	NOUN
cusj-10967	291	28	inhibition	inhibition	NOUN
cusj-10967	291	29	in	in	ADP
cusj-10967	291	30	uveal	uveal	ADJ
cusj-10967	291	31	melanoma	melanoma	NOUN
cusj-10967	291	32	xenograft	xenograft	NOUN
cusj-10967	291	33	.	.	PUNCT
cusj-10967	292	1	cancer	cancer	NOUN
cusj-10967	292	2	lett	lett	PROPN
cusj-10967	292	3	495	495	NUM
cusj-10967	292	4	,	,	PUNCT
cusj-10967	292	5	123	123	NUM
cusj-10967	292	6	-	-	SYM
cusj-10967	292	7	134	134	NUM
cusj-10967	292	8	(	(	PUNCT
cusj-10967	292	9	2020	2020	NUM
cusj-10967	292	10	)	)	PUNCT
cusj-10967	292	11	.	.	PUNCT
cusj-10967	293	1	[	[	X
cusj-10967	293	2	25	25	NUM
cusj-10967	293	3	]	]	X
cusj-10967	293	4	h.	h.	PROPN
cusj-10967	293	5	khalique	khalique	PROPN
cusj-10967	293	6	et	et	PROPN
cusj-10967	293	7	al	al	PROPN
cusj-10967	293	8	.	.	PROPN
cusj-10967	293	9	,	,	PUNCT
cusj-10967	293	10	oncolytic	oncolytic	ADJ
cusj-10967	293	11	herpesvirus	herpesvirus	NOUN
cusj-10967	293	12	expressing	express	VERB
cusj-10967	293	13	pd	pd	PROPN
cusj-10967	293	14	-	-	PROPN
cusj-10967	293	15	l1	l1	PROPN
cusj-10967	293	16	bite	bite	NOUN
cusj-10967	293	17	for	for	ADP
cusj-10967	293	18	cancer	cancer	NOUN
cusj-10967	293	19	therapy	therapy	NOUN
cusj-10967	293	20	:	:	PUNCT
cusj-10967	293	21	exploiting	exploit	VERB
cusj-10967	293	22	tumor	tumor	NOUN
cusj-10967	293	23	immune	immune	ADJ
cusj-10967	293	24	suppression	suppression	NOUN
cusj-10967	293	25	as	as	ADP
cusj-10967	293	26	an	an	DET
cusj-10967	293	27	opportunity	opportunity	NOUN
cusj-10967	293	28	for	for	ADP
cusj-10967	293	29	targeted	target	VERB
cusj-10967	293	30	immunotherapy	immunotherapy	NOUN
cusj-10967	293	31	.	.	PUNCT
cusj-10967	294	1	j	j	PROPN
cusj-10967	294	2	immunother	immunother	ADJ
cusj-10967	294	3	cancer	cancer	NOUN
cusj-10967	294	4	9	9	NUM
cusj-10967	294	5	,	,	PUNCT
cusj-10967	294	6	(	(	PUNCT
cusj-10967	294	7	2021	2021	NUM
cusj-10967	294	8	)	)	PUNCT
cusj-10967	294	9	.	.	PUNCT
cusj-10967	295	1	[	[	X
cusj-10967	295	2	26	26	NUM
cusj-10967	295	3	]	]	PUNCT
cusj-10967	295	4	v.	v.	CCONJ
cusj-10967	295	5	leoni	leoni	X
cusj-10967	295	6	et	et	PROPN
cusj-10967	295	7	al	al	PROPN
cusj-10967	295	8	.	.	PROPN
cusj-10967	295	9	,	,	PUNCT
cusj-10967	295	10	a	a	DET
cusj-10967	295	11	strategy	strategy	NOUN
cusj-10967	295	12	for	for	ADP
cusj-10967	295	13	cultivation	cultivation	NOUN
cusj-10967	295	14	of	of	ADP
cusj-10967	295	15	retargeted	retargete	VERB
cusj-10967	295	16	oncolytic	oncolytic	ADJ
cusj-10967	295	17	herpes	herpe	NOUN
cusj-10967	295	18	simplex	simplex	NOUN
cusj-10967	295	19	viruses	virus	NOUN
cusj-10967	295	20	in	in	ADP
cusj-10967	295	21	non	non	ADJ
cusj-10967	295	22	-	-	ADJ
cusj-10967	295	23	cancer	cancer	ADJ
cusj-10967	295	24	cells	cell	NOUN
cusj-10967	295	25	.	.	PUNCT
cusj-10967	296	1	j	j	PROPN
cusj-10967	296	2	virol	virol	PROPN
cusj-10967	296	3	91	91	NUM
cusj-10967	296	4	,	,	PUNCT
cusj-10967	296	5	(	(	PUNCT
cusj-10967	296	6	2017	2017	NUM
cusj-10967	296	7	)	)	PUNCT
cusj-10967	296	8	.	.	PUNCT
cusj-10967	297	1	[	[	X
cusj-10967	297	2	27	27	NUM
cusj-10967	297	3	]	]	X
cusj-10967	297	4	d.	d.	PROPN
cusj-10967	297	5	g.	g.	PROPN
cusj-10967	297	6	roy	roy	PROPN
cusj-10967	297	7	et	et	PROPN
cusj-10967	297	8	al	al	PROPN
cusj-10967	297	9	.	.	PROPN
cusj-10967	297	10	,	,	PUNCT
cusj-10967	297	11	adjuvant	adjuvant	ADJ
cusj-10967	297	12	oncolytic	oncolytic	PROPN
cusj-10967	297	13	virotherapy	virotherapy	NOUN
cusj-10967	297	14	for	for	ADP
cusj-10967	297	15	personalized	personalize	VERB
cusj-10967	297	16	anti	anti	ADJ
cusj-10967	297	17	-	-	ADJ
cusj-10967	297	18	cancer	cancer	ADJ
cusj-10967	297	19	vaccination	vaccination	NOUN
cusj-10967	297	20	.	.	PUNCT
cusj-10967	298	1	nat	nat	PROPN
cusj-10967	298	2	commun	commun	PROPN
cusj-10967	298	3	12	12	NUM
cusj-10967	298	4	,	,	PUNCT
cusj-10967	298	5	2626	2626	NUM
cusj-10967	298	6	(	(	PUNCT
cusj-10967	298	7	2021	2021	NUM
cusj-10967	298	8	)	)	PUNCT
cusj-10967	298	9	.	.	PUNCT
cusj-10967	299	1	[	[	X
cusj-10967	299	2	28	28	NUM
cusj-10967	299	3	]	]	X
cusj-10967	299	4	c.	c.	PROPN
cusj-10967	299	5	tian	tian	PROPN
cusj-10967	299	6	et	et	PROPN
cusj-10967	299	7	al	al	PROPN
cusj-10967	299	8	.	.	PROPN
cusj-10967	299	9	,	,	PUNCT
cusj-10967	299	10	enhanced	enhance	VERB
cusj-10967	299	11	anti	anti	ADJ
cusj-10967	299	12	-	-	ADJ
cusj-10967	299	13	tumor	tumor	ADJ
cusj-10967	299	14	response	response	NOUN
cusj-10967	299	15	elicited	elicit	VERB
cusj-10967	299	16	by	by	ADP
cusj-10967	299	17	a	a	DET
cusj-10967	299	18	novel	novel	ADJ
cusj-10967	299	19	oncolytic	oncolytic	NOUN
cusj-10967	299	20	hsv-1	hsv-1	ADV
cusj-10967	299	21	engineered	engineer	VERB
cusj-10967	299	22	with	with	ADP
cusj-10967	299	23	an	an	DET
cusj-10967	299	24	anti	anti	ADJ
cusj-10967	299	25	-	-	ADJ
cusj-10967	299	26	pd-1	pd-1	ADJ
cusj-10967	299	27	antibody	antibody	NOUN
cusj-10967	299	28	.	.	PUNCT
cusj-10967	300	1	cancer	cancer	NOUN
cusj-10967	300	2	lett	lett	PROPN
cusj-10967	300	3	518	518	NUM
cusj-10967	300	4	,	,	PUNCT
cusj-10967	300	5	49	49	NUM
cusj-10967	300	6	-	-	SYM
cusj-10967	300	7	58	58	NUM
cusj-10967	300	8	(	(	PUNCT
cusj-10967	300	9	2021	2021	NUM
cusj-10967	300	10	)	)	PUNCT
cusj-10967	300	11	.	.	PUNCT
cusj-10967	301	1	[	[	X
cusj-10967	301	2	29	29	NUM
cusj-10967	301	3	]	]	PUNCT
cusj-10967	301	4	s.	s.	PROPN
cusj-10967	301	5	thomas	thomas	PROPN
cusj-10967	301	6	et	et	PROPN
cusj-10967	301	7	al	al	PROPN
cusj-10967	301	8	.	.	PROPN
cusj-10967	301	9	,	,	PUNCT
cusj-10967	301	10	development	development	NOUN
cusj-10967	301	11	of	of	ADP
cusj-10967	301	12	a	a	DET
cusj-10967	301	13	new	new	ADJ
cusj-10967	301	14	fusion	fusion	NOUN
cusj-10967	301	15	-	-	PUNCT
cusj-10967	301	16	enhanced	enhance	VERB
cusj-10967	301	17	oncolytic	oncolytic	ADJ
cusj-10967	301	18	immunotherapy	immunotherapy	NOUN
cusj-10967	301	19	platform	platform	NOUN
cusj-10967	301	20	based	base	VERB
cusj-10967	301	21	on	on	ADP
cusj-10967	301	22	herpes	herpe	NOUN
cusj-10967	301	23	simplex	simplex	NOUN
cusj-10967	301	24	virus	virus	NOUN
cusj-10967	301	25	type	type	NOUN
cusj-10967	301	26	1	1	NUM
cusj-10967	301	27	.	.	PUNCT
cusj-10967	302	1	j	j	PROPN
cusj-10967	302	2	immunother	immunother	PROPN
cusj-10967	302	3	cancer	cancer	NOUN
cusj-10967	302	4	7	7	NUM
cusj-10967	302	5	,	,	PUNCT
cusj-10967	302	6	214	214	NUM
cusj-10967	302	7	(	(	PUNCT
cusj-10967	302	8	2019	2019	NUM
cusj-10967	302	9	)	)	PUNCT
cusj-10967	302	10	.	.	PUNCT
cusj-10967	303	1	[	[	X
cusj-10967	303	2	30	30	NUM
cusj-10967	303	3	]	]	X
cusj-10967	303	4	m.	m.	NOUN
cusj-10967	303	5	m.	m.	PROPN
cusj-10967	303	6	rahman	rahman	PROPN
cusj-10967	303	7	,	,	PUNCT
cusj-10967	303	8	g.	g.	PROPN
cusj-10967	303	9	mcfadden	mcfadden	PROPN
cusj-10967	303	10	,	,	PUNCT
cusj-10967	303	11	oncolytic	oncolytic	ADJ
cusj-10967	303	12	viruses	virus	NOUN
cusj-10967	303	13	:	:	PUNCT
cusj-10967	303	14	newest	new	ADJ
cusj-10967	303	15	frontier	frontier	NOUN
cusj-10967	303	16	for	for	ADP
cusj-10967	303	17	cancer	cancer	NOUN
cusj-10967	303	18	immunotherapy	immunotherapy	NOUN
cusj-10967	303	19	.	.	PUNCT
cusj-10967	304	1	cancers	cancer	NOUN
cusj-10967	304	2	(	(	PUNCT
cusj-10967	304	3	basel	basel	PROPN
cusj-10967	304	4	)	)	PUNCT
cusj-10967	304	5	13	13	NUM
cusj-10967	304	6	,	,	PUNCT
cusj-10967	304	7	(	(	PUNCT
cusj-10967	304	8	2021	2021	NUM
cusj-10967	304	9	)	)	PUNCT
cusj-10967	304	10	.	.	PUNCT
cusj-10967	305	1	[	[	X
cusj-10967	305	2	31	31	NUM
cusj-10967	305	3	]	]	X
cusj-10967	305	4	d.	d.	PROPN
cusj-10967	305	5	aldinucci	aldinucci	PROPN
cusj-10967	305	6	,	,	PUNCT
cusj-10967	305	7	c.	c.	PROPN
cusj-10967	305	8	borghese	borghese	PROPN
cusj-10967	305	9	,	,	PUNCT
cusj-10967	305	10	n.	n.	PROPN
cusj-10967	305	11	casagrande	casagrande	PROPN
cusj-10967	305	12	,	,	PUNCT
cusj-10967	305	13	the	the	DET
cusj-10967	305	14	ccl5	ccl5	PROPN
cusj-10967	305	15	/	/	SYM
cusj-10967	305	16	ccr5	ccr5	NOUN
cusj-10967	305	17	axis	axis	NOUN
cusj-10967	305	18	in	in	ADP
cusj-10967	305	19	cancer	cancer	NOUN
cusj-10967	305	20	progression	progression	NOUN
cusj-10967	305	21	.	.	PUNCT
cusj-10967	306	1	cancers	cancer	NOUN
cusj-10967	306	2	(	(	PUNCT
cusj-10967	306	3	basel	basel	PROPN
cusj-10967	306	4	)	)	PUNCT
cusj-10967	306	5	12	12	NUM
cusj-10967	306	6	,	,	PUNCT
cusj-10967	306	7	(	(	PUNCT
cusj-10967	306	8	2020	2020	NUM
cusj-10967	306	9	)	)	PUNCT
cusj-10967	306	10	.	.	PUNCT
cusj-10967	307	1	[	[	X
cusj-10967	307	2	32	32	NUM
cusj-10967	307	3	]	]	PUNCT
cusj-10967	307	4	f.	f.	PROPN
cusj-10967	307	5	li	li	PROPN
cusj-10967	307	6	et	et	PROPN
cusj-10967	307	7	al	al	PROPN
cusj-10967	307	8	.	.	PROPN
cusj-10967	307	9	,	,	PUNCT
cusj-10967	307	10	ccl5	ccl5	PROPN
cusj-10967	307	11	-	-	PUNCT
cusj-10967	307	12	armed	arm	VERB
cusj-10967	307	13	oncolytic	oncolytic	ADJ
cusj-10967	307	14	virus	virus	NOUN
cusj-10967	307	15	augments	augment	VERB
cusj-10967	307	16	ccr5	ccr5	NOUN
cusj-10967	307	17	-	-	PUNCT
cusj-10967	307	18	engineered	engineer	VERB
cusj-10967	307	19	nk	nk	PROPN
cusj-10967	307	20	cell	cell	NOUN
cusj-10967	307	21	infiltration	infiltration	NOUN
cusj-10967	307	22	and	and	CCONJ
cusj-10967	307	23	antitumor	antitumor	PROPN
cusj-10967	307	24	efficiency	efficiency	NOUN
cusj-10967	307	25	.	.	PUNCT
cusj-10967	308	1	j	j	PROPN
cusj-10967	308	2	immunother	immunother	PROPN
cusj-10967	308	3	cancer	cancer	NOUN
cusj-10967	308	4	8	8	NUM
cusj-10967	308	5	,	,	PUNCT
cusj-10967	308	6	(	(	PUNCT
cusj-10967	308	7	2020	2020	NUM
cusj-10967	308	8	)	)	PUNCT
cusj-10967	308	9	.	.	PUNCT
cusj-10967	309	1	[	[	X
cusj-10967	309	2	33	33	NUM
cusj-10967	309	3	]	]	X
cusj-10967	309	4	g.	g.	PROPN
cusj-10967	309	5	vijayakumar	vijayakumar	PROPN
cusj-10967	309	6	,	,	PUNCT
cusj-10967	309	7	s.	s.	PROPN
cusj-10967	309	8	mccroskery	mccroskery	PROPN
cusj-10967	309	9	,	,	PUNCT
cusj-10967	309	10	p.	p.	PROPN
cusj-10967	309	11	palese	palese	NOUN
cusj-10967	309	12	,	,	PUNCT
cusj-10967	309	13	engineering	engineering	NOUN
cusj-10967	309	14	newcastle	newcastle	PROPN
cusj-10967	309	15	disease	disease	PROPN
cusj-10967	309	16	virus	virus	NOUN
cusj-10967	309	17	as	as	ADP
cusj-10967	309	18	an	an	DET
cusj-10967	309	19	oncolytic	oncolytic	ADJ
cusj-10967	309	20	vector	vector	NOUN
cusj-10967	309	21	for	for	ADP
cusj-10967	309	22	intratumoral	intratumoral	ADJ
cusj-10967	309	23	delivery	delivery	NOUN
cusj-10967	309	24	of	of	ADP
cusj-10967	309	25	immune	immune	ADJ
cusj-10967	309	26	checkpoint	checkpoint	NOUN
cusj-10967	309	27	inhibitors	inhibitor	NOUN
cusj-10967	309	28	and	and	CCONJ
cusj-10967	309	29	immunocytokines	immunocytokine	NOUN
cusj-10967	309	30	.	.	PUNCT
cusj-10967	310	1	j	j	PROPN
cusj-10967	310	2	virol	virol	PROPN
cusj-10967	310	3	94	94	NUM
cusj-10967	310	4	,	,	PUNCT
cusj-10967	310	5	(	(	PUNCT
cusj-10967	310	6	2020	2020	NUM
cusj-10967	310	7	)	)	PUNCT
cusj-10967	310	8	.	.	PUNCT
cusj-10967	311	1	[	[	X
cusj-10967	311	2	34	34	NUM
cusj-10967	311	3	]	]	PUNCT
cusj-10967	311	4	s.	s.	PROPN
cusj-10967	311	5	zuo	zuo	PROPN
cusj-10967	311	6	et	et	PROPN
cusj-10967	311	7	al	al	PROPN
cusj-10967	311	8	.	.	PROPN
cusj-10967	311	9	,	,	PUNCT
cusj-10967	311	10	an	an	DET
cusj-10967	311	11	engineered	engineer	VERB
cusj-10967	311	12	oncolytic	oncolytic	ADJ
cusj-10967	311	13	vaccinia	vaccinia	NOUN
cusj-10967	311	14	virus	virus	NOUN
cusj-10967	311	15	encoding	encode	VERB
cusj-10967	311	16	a	a	DET
cusj-10967	311	17	single	single	ADJ
cusj-10967	311	18	-	-	PUNCT
cusj-10967	311	19	chain	chain	NOUN
cusj-10967	311	20	variable	variable	NOUN
cusj-10967	311	21	fragment	fragment	NOUN
cusj-10967	311	22	against	against	ADP
cusj-10967	311	23	tigit	tigit	NOUN
cusj-10967	311	24	induces	induce	VERB
cusj-10967	311	25	effective	effective	ADJ
cusj-10967	311	26	antitumor	antitumor	NOUN
cusj-10967	311	27	immunity	immunity	NOUN
cusj-10967	311	28	and	and	CCONJ
cusj-10967	311	29	synergizes	synergize	VERB
cusj-10967	311	30	with	with	ADP
cusj-10967	311	31	pd-1	pd-1	ADJ
cusj-10967	311	32	or	or	CCONJ
cusj-10967	311	33	lag-3	lag-3	PUNCT
cusj-10967	311	34	blockade	blockade	NOUN
cusj-10967	311	35	.	.	PUNCT
cusj-10967	312	1	j	j	PROPN
cusj-10967	312	2	immunother	immunother	ADJ
cusj-10967	312	3	cancer	cancer	NOUN
cusj-10967	312	4	9	9	NUM
cusj-10967	312	5	,	,	PUNCT
cusj-10967	312	6	(	(	PUNCT
cusj-10967	312	7	2021	2021	NUM
cusj-10967	312	8	)	)	PUNCT
cusj-10967	312	9	.	.	PUNCT
cusj-10967	313	1	[	[	X
cusj-10967	313	2	35	35	NUM
cusj-10967	313	3	]	]	X
cusj-10967	313	4	g.	g.	PROPN
cusj-10967	313	5	wang	wang	PROPN
cusj-10967	313	6	et	et	PROPN
cusj-10967	313	7	al	al	PROPN
cusj-10967	313	8	.	.	PROPN
cusj-10967	313	9	,	,	PUNCT
cusj-10967	313	10	an	an	DET
cusj-10967	313	11	engineered	engineer	VERB
cusj-10967	313	12	oncolytic	oncolytic	ADJ
cusj-10967	313	13	virus	virus	NOUN
cusj-10967	313	14	expressing	express	VERB
cusj-10967	313	15	pd	pd	PROPN
cusj-10967	313	16	-	-	PUNCT
cusj-10967	313	17	l1	l1	PROPN
cusj-10967	313	18	inhibitors	inhibitor	NOUN
cusj-10967	313	19	activates	activate	VERB
cusj-10967	313	20	tumor	tumor	NOUN
cusj-10967	313	21	neoantigenspecific	neoantigenspecific	PROPN
cusj-10967	313	22	t	t	PROPN
cusj-10967	313	23	cell	cell	NOUN
cusj-10967	313	24	responses	response	NOUN
cusj-10967	313	25	.	.	PUNCT
cusj-10967	314	1	nat	nat	PROPN
cusj-10967	314	2	commun	commun	PROPN
cusj-10967	314	3	11	11	NUM
cusj-10967	314	4	,	,	PUNCT
cusj-10967	314	5	1395	1395	NUM
cusj-10967	314	6	(	(	PUNCT
cusj-10967	314	7	2020	2020	NUM
cusj-10967	314	8	)	)	PUNCT
cusj-10967	314	9	.	.	PUNCT
cusj-10967	315	1	[	[	X
cusj-10967	315	2	36	36	NUM
cusj-10967	315	3	]	]	X
cusj-10967	315	4	c.	c.	PROPN
cusj-10967	315	5	wu	wu	PROPN
cusj-10967	315	6	,	,	PUNCT
cusj-10967	315	7	m.	m.	PROPN
cusj-10967	315	8	wu	wu	PROPN
cusj-10967	315	9	,	,	PUNCT
cusj-10967	315	10	m.	m.	PROPN
cusj-10967	315	11	liang	liang	PROPN
cusj-10967	315	12	,	,	PUNCT
cusj-10967	315	13	s.	s.	PROPN
cusj-10967	315	14	xiong	xiong	PROPN
cusj-10967	315	15	,	,	PUNCT
cusj-10967	315	16	c.	c.	PROPN
cusj-10967	315	17	dong	dong	PROPN
cusj-10967	315	18	,	,	PUNCT
cusj-10967	315	19	a	a	DET
cusj-10967	315	20	novel	novel	ADJ
cusj-10967	315	21	oncolytic	oncolytic	ADJ
cusj-10967	315	22	virus	virus	NOUN
cusj-10967	315	23	engineered	engineer	VERB
cusj-10967	315	24	with	with	ADP
cusj-10967	315	25	pd	pd	PROPN
cusj-10967	315	26	-	-	PROPN
cusj-10967	315	27	l1	l1	PROPN
cusj-10967	315	28	scfv	scfv	PROPN
cusj-10967	315	29	effectively	effectively	ADV
cusj-10967	315	30	inhibits	inhibit	VERB
cusj-10967	315	31	columbia	columbia	PROPN
cusj-10967	315	32	undergraduate	undergraduate	PROPN
cusj-10967	315	33	science	science	PROPN
cusj-10967	315	34	journal	journal	PROPN
cusj-10967	315	35	vol	vol	NOUN
cusj-10967	315	36	.	.	PROPN
cusj-10967	315	37	18	18	NUM
cusj-10967	315	38	,	,	PUNCT
cusj-10967	315	39	2024	2024	NUM
cusj-10967	315	40	manjila	manjila	PROPN
cusj-10967	315	41	tumor	tumor	NOUN
cusj-10967	315	42	growth	growth	NOUN
cusj-10967	315	43	in	in	ADP
cusj-10967	315	44	a	a	DET
cusj-10967	315	45	mouse	mouse	NOUN
cusj-10967	315	46	model	model	NOUN
cusj-10967	315	47	.	.	PUNCT
cusj-10967	316	1	cell	cell	NOUN
cusj-10967	316	2	mol	mol	ADP
cusj-10967	316	3	immunol	immunol	NOUN
cusj-10967	316	4	16	16	NUM
cusj-10967	316	5	,	,	PUNCT
cusj-10967	316	6	780	780	NUM
cusj-10967	316	7	-	-	SYM
cusj-10967	316	8	782	782	NUM
cusj-10967	316	9	(	(	PUNCT
cusj-10967	316	10	2019	2019	NUM
cusj-10967	316	11	)	)	PUNCT
cusj-10967	316	12	.	.	PUNCT
cusj-10967	317	1	[	[	X
cusj-10967	317	2	37	37	NUM
cusj-10967	317	3	]	]	PUNCT
cusj-10967	317	4	r.	r.	PROPN
cusj-10967	317	5	w.	w.	PROPN
cusj-10967	317	6	walton	walton	PROPN
cusj-10967	317	7	,	,	PUNCT
cusj-10967	317	8	m.	m.	PROPN
cusj-10967	317	9	c.	c.	PROPN
cusj-10967	317	10	brown	brown	PROPN
cusj-10967	317	11	,	,	PUNCT
cusj-10967	317	12	m.	m.	NOUN
cusj-10967	317	13	t.	t.	PROPN
cusj-10967	317	14	sacco	sacco	PROPN
cusj-10967	317	15	,	,	PUNCT
cusj-10967	317	16	m.	m.	NOUN
cusj-10967	317	17	gromeier	gromeier	NOUN
cusj-10967	317	18	,	,	PUNCT
cusj-10967	317	19	engineered	engineer	VERB
cusj-10967	317	20	oncolytic	oncolytic	ADJ
cusj-10967	317	21	poliovirus	poliovirus	NOUN
cusj-10967	317	22	pvsripo	pvsripo	NOUN
cusj-10967	317	23	subverts	subvert	VERB
cusj-10967	317	24	mda5	mda5	NOUN
cusj-10967	317	25	-	-	PUNCT
cusj-10967	317	26	dependent	dependent	ADJ
cusj-10967	317	27	innate	innate	ADJ
cusj-10967	317	28	immune	immune	ADJ
cusj-10967	317	29	responses	response	NOUN
cusj-10967	317	30	in	in	ADP
cusj-10967	317	31	cancer	cancer	NOUN
cusj-10967	317	32	cells	cell	NOUN
cusj-10967	317	33	.	.	PUNCT
cusj-10967	318	1	j	j	PROPN
cusj-10967	318	2	virol	virol	NOUN
cusj-10967	318	3	92	92	NUM
cusj-10967	318	4	,	,	PUNCT
cusj-10967	318	5	(	(	PUNCT
cusj-10967	318	6	2018	2018	NUM
cusj-10967	318	7	)	)	PUNCT
cusj-10967	318	8	.	.	PUNCT
cusj-10967	319	1	[	[	X
cusj-10967	319	2	38	38	NUM
cusj-10967	319	3	]	]	PUNCT
cusj-10967	319	4	r.	r.	PROPN
cusj-10967	319	5	m.	m.	PROPN
cusj-10967	319	6	rodriguez	rodriguez	PROPN
cusj-10967	319	7	stewart	stewart	PROPN
cusj-10967	319	8	,	,	PUNCT
cusj-10967	319	9	v.	v.	ADP
cusj-10967	319	10	raghuram	raghuram	PROPN
cusj-10967	319	11	,	,	PUNCT
cusj-10967	319	12	j.	j.	PROPN
cusj-10967	319	13	t.	t.	PROPN
cusj-10967	319	14	l.	l.	PROPN
cusj-10967	319	15	berry	berry	PROPN
cusj-10967	319	16	,	,	PUNCT
cusj-10967	319	17	g.	g.	PROPN
cusj-10967	319	18	n.	n.	PROPN
cusj-10967	319	19	joshi	joshi	PROPN
cusj-10967	319	20	,	,	PUNCT
cusj-10967	319	21	b.	b.	PROPN
cusj-10967	319	22	a.	a.	NOUN
cusj-10967	319	23	mainou	mainou	PROPN
cusj-10967	319	24	,	,	PUNCT
cusj-10967	319	25	noncanonical	noncanonical	ADJ
cusj-10967	319	26	cell	cell	NOUN
cusj-10967	319	27	death	death	NOUN
cusj-10967	319	28	induction	induction	NOUN
cusj-10967	319	29	by	by	ADP
cusj-10967	319	30	reassortant	reassortant	ADJ
cusj-10967	319	31	reovirus	reovirus	PROPN
cusj-10967	319	32	.	.	PUNCT
cusj-10967	320	1	j	j	PROPN
cusj-10967	320	2	virol	virol	PROPN
cusj-10967	320	3	94	94	NUM
cusj-10967	320	4	,	,	PUNCT
cusj-10967	320	5	(	(	PUNCT
cusj-10967	320	6	2020	2020	NUM
cusj-10967	320	7	)	)	PUNCT
cusj-10967	320	8	.	.	PUNCT
cusj-10967	321	1	[	[	X
cusj-10967	321	2	39	39	NUM
cusj-10967	321	3	]	]	PUNCT
cusj-10967	321	4	s.	s.	PROPN
cusj-10967	321	5	l.	l.	PROPN
cusj-10967	321	6	seegers	seegers	PROPN
cusj-10967	321	7	,	,	PUNCT
cusj-10967	321	8	c.	c.	PROPN
cusj-10967	321	9	frasier	frasier	PROPN
cusj-10967	321	10	,	,	PUNCT
cusj-10967	321	11	s.	s.	PROPN
cusj-10967	321	12	greene	greene	PROPN
cusj-10967	321	13	,	,	PUNCT
cusj-10967	321	14	i.	i.	PROPN
cusj-10967	321	15	v.	v.	PROPN
cusj-10967	321	16	nesmelova	nesmelova	PROPN
cusj-10967	321	17	,	,	PUNCT
cusj-10967	321	18	v.	v.	PROPN
cusj-10967	321	19	z.	z.	PROPN
cusj-10967	321	20	grdzelishvili	grdzelishvili	PROPN
cusj-10967	321	21	,	,	PUNCT
cusj-10967	321	22	experimental	experimental	ADJ
cusj-10967	321	23	evolution	evolution	NOUN
cusj-10967	321	24	generates	generate	VERB
cusj-10967	321	25	novel	novel	ADJ
cusj-10967	321	26	oncolytic	oncolytic	ADJ
cusj-10967	321	27	vesicular	vesicular	ADJ
cusj-10967	321	28	stomatitis	stomatitis	NOUN
cusj-10967	321	29	viruses	virus	NOUN
cusj-10967	321	30	with	with	ADP
cusj-10967	321	31	improved	improved	ADJ
cusj-10967	321	32	replication	replication	NOUN
cusj-10967	321	33	in	in	ADP
cusj-10967	321	34	virusresistant	virusresistant	ADJ
cusj-10967	321	35	pancreatic	pancreatic	ADJ
cusj-10967	321	36	cancer	cancer	NOUN
cusj-10967	321	37	cells	cell	NOUN
cusj-10967	321	38	.	.	PUNCT
cusj-10967	322	1	j	j	PROPN
cusj-10967	322	2	virol	virol	PROPN
cusj-10967	322	3	94	94	NUM
cusj-10967	322	4	,	,	PUNCT
cusj-10967	322	5	(	(	PUNCT
cusj-10967	322	6	2020	2020	NUM
cusj-10967	322	7	)	)	PUNCT
cusj-10967	322	8	.	.	PUNCT
cusj-10967	323	1	[	[	X
cusj-10967	323	2	40	40	NUM
cusj-10967	323	3	]	]	PUNCT
cusj-10967	323	4	r.	r.	PROPN
cusj-10967	323	5	c.	c.	PROPN
cusj-10967	323	6	sterner	sterner	PROPN
cusj-10967	323	7	,	,	PUNCT
cusj-10967	323	8	r.	r.	PROPN
cusj-10967	323	9	m.	m.	PROPN
cusj-10967	323	10	sterner	stern	ADJ
cusj-10967	323	11	,	,	PUNCT
cusj-10967	323	12	car	car	NOUN
cusj-10967	323	13	-	-	PUNCT
cusj-10967	323	14	t	t	NOUN
cusj-10967	323	15	cell	cell	NOUN
cusj-10967	323	16	therapy	therapy	NOUN
cusj-10967	323	17	:	:	PUNCT
cusj-10967	323	18	current	current	ADJ
cusj-10967	323	19	limitations	limitation	NOUN
cusj-10967	323	20	and	and	CCONJ
cusj-10967	323	21	potential	potential	ADJ
cusj-10967	323	22	strategies	strategy	NOUN
cusj-10967	323	23	.	.	PUNCT
cusj-10967	324	1	blood	blood	NOUN
cusj-10967	324	2	cancer	cancer	NOUN
cusj-10967	324	3	j	j	PROPN
cusj-10967	324	4	11	11	NUM
cusj-10967	324	5	,	,	PUNCT
cusj-10967	324	6	69	69	NUM
cusj-10967	324	7	(	(	PUNCT
cusj-10967	324	8	2021	2021	NUM
cusj-10967	324	9	)	)	PUNCT
cusj-10967	324	10	.	.	PUNCT
cusj-10967	325	1	[	[	X
cusj-10967	325	2	41	41	NUM
cusj-10967	325	3	]	]	PUNCT
cusj-10967	325	4	m.	m.	NOUN
cusj-10967	325	5	k.	k.	PROPN
cusj-10967	325	6	mckenna	mckenna	PROPN
cusj-10967	325	7	et	et	PROPN
cusj-10967	325	8	al	al	PROPN
cusj-10967	325	9	.	.	PROPN
cusj-10967	325	10	,	,	PUNCT
cusj-10967	325	11	mesenchymal	mesenchymal	ADJ
cusj-10967	325	12	stromal	stromal	ADJ
cusj-10967	325	13	cell	cell	NOUN
cusj-10967	325	14	delivery	delivery	NOUN
cusj-10967	325	15	of	of	ADP
cusj-10967	325	16	oncolytic	oncolytic	ADJ
cusj-10967	325	17	immunotherapy	immunotherapy	NOUN
cusj-10967	325	18	improves	improve	VERB
cusj-10967	325	19	car	car	NOUN
cusj-10967	325	20	-	-	PUNCT
cusj-10967	325	21	t	t	NOUN
cusj-10967	325	22	cell	cell	NOUN
cusj-10967	325	23	antitumor	antitumor	PROPN
cusj-10967	325	24	activity	activity	NOUN
cusj-10967	325	25	.	.	PUNCT
cusj-10967	326	1	mol	mol	ADP
cusj-10967	326	2	ther	ther	ADJ
cusj-10967	326	3	29	29	NUM
cusj-10967	326	4	,	,	PUNCT
cusj-10967	326	5	18081820	18081820	NUM
cusj-10967	326	6	(	(	PUNCT
cusj-10967	326	7	2021	2021	NUM
cusj-10967	326	8	)	)	PUNCT
cusj-10967	326	9	.	.	PUNCT
cusj-10967	327	1	[	[	X
cusj-10967	327	2	42	42	NUM
cusj-10967	327	3	]	]	PUNCT
cusj-10967	327	4	g.	g.	PROPN
cusj-10967	327	5	froechlich	froechlich	PROPN
cusj-10967	327	6	et	et	PROPN
cusj-10967	327	7	al	al	PROPN
cusj-10967	327	8	.	.	PROPN
cusj-10967	327	9	,	,	PUNCT
cusj-10967	327	10	generation	generation	NOUN
cusj-10967	327	11	of	of	ADP
cusj-10967	327	12	a	a	DET
cusj-10967	327	13	novel	novel	ADJ
cusj-10967	327	14	mesothelin	mesothelin	NOUN
cusj-10967	327	15	-	-	PUNCT
cusj-10967	327	16	targeted	target	VERB
cusj-10967	327	17	oncolytic	oncolytic	ADJ
cusj-10967	327	18	herpes	herpe	NOUN
cusj-10967	327	19	virus	virus	NOUN
cusj-10967	327	20	and	and	CCONJ
cusj-10967	327	21	implemented	implement	VERB
cusj-10967	327	22	strategies	strategy	NOUN
cusj-10967	327	23	for	for	ADP
cusj-10967	327	24	manufacturing	manufacturing	NOUN
cusj-10967	327	25	.	.	PUNCT
cusj-10967	328	1	int	int	PROPN
cusj-10967	328	2	j	j	PROPN
cusj-10967	328	3	mol	mol	ADP
cusj-10967	328	4	sci	sci	PROPN
cusj-10967	328	5	22	22	NUM
cusj-10967	328	6	,	,	PUNCT
cusj-10967	328	7	(	(	PUNCT
cusj-10967	328	8	2021	2021	NUM
cusj-10967	328	9	)	)	PUNCT
cusj-10967	328	10	.	.	PUNCT
cusj-10967	329	1	[	[	X
cusj-10967	329	2	43	43	NUM
cusj-10967	329	3	]	]	X
cusj-10967	329	4	h.	h.	PROPN
cusj-10967	329	5	huang	huang	PROPN
cusj-10967	329	6	et	et	PROPN
cusj-10967	329	7	al	al	PROPN
cusj-10967	329	8	.	.	PROPN
cusj-10967	329	9	,	,	PUNCT
cusj-10967	329	10	oncolytic	oncolytic	ADJ
cusj-10967	329	11	adenovirus	adenovirus	NOUN
cusj-10967	329	12	programmed	program	VERB
cusj-10967	329	13	by	by	ADP
cusj-10967	329	14	synthetic	synthetic	ADJ
cusj-10967	329	15	gene	gene	NOUN
cusj-10967	329	16	circuit	circuit	NOUN
cusj-10967	329	17	for	for	ADP
cusj-10967	329	18	cancer	cancer	NOUN
cusj-10967	329	19	immunotherapy	immunotherapy	NOUN
cusj-10967	329	20	.	.	PUNCT
cusj-10967	330	1	nat	nat	PROPN
cusj-10967	330	2	commun	commun	PROPN
cusj-10967	330	3	10	10	NUM
cusj-10967	330	4	,	,	PUNCT
cusj-10967	330	5	4801	4801	NUM
cusj-10967	330	6	(	(	PUNCT
cusj-10967	330	7	2019	2019	NUM
cusj-10967	330	8	)	)	PUNCT
cusj-10967	330	9	.	.	PUNCT
cusj-10967	331	1	[	[	X
cusj-10967	331	2	44	44	NUM
cusj-10967	331	3	]	]	PUNCT
cusj-10967	331	4	a.	a.	PROPN
cusj-10967	331	5	k.	k.	PROPN
cusj-10967	331	6	park	park	PROPN
cusj-10967	331	7	et	et	PROPN
cusj-10967	332	1	al	al	PROPN
cusj-10967	332	2	.	.	PROPN
cusj-10967	332	3	,	,	PUNCT
cusj-10967	332	4	effective	effective	ADJ
cusj-10967	332	5	combination	combination	NOUN
cusj-10967	332	6	immunotherapy	immunotherapy	NOUN
cusj-10967	332	7	using	use	VERB
cusj-10967	332	8	oncolytic	oncolytic	ADJ
cusj-10967	332	9	viruses	virus	NOUN
cusj-10967	332	10	to	to	PART
cusj-10967	332	11	deliver	deliver	VERB
cusj-10967	332	12	car	car	NOUN
cusj-10967	332	13	targets	target	NOUN
cusj-10967	332	14	to	to	ADP
cusj-10967	332	15	solid	solid	ADJ
cusj-10967	332	16	tumors	tumor	NOUN
cusj-10967	332	17	.	.	PUNCT
cusj-10967	333	1	sci	sci	PROPN
cusj-10967	333	2	transl	transl	PROPN
cusj-10967	333	3	med	med	PROPN
cusj-10967	333	4	12	12	NUM
cusj-10967	333	5	,	,	PUNCT
cusj-10967	333	6	(	(	PUNCT
cusj-10967	333	7	2020	2020	NUM
cusj-10967	333	8	)	)	PUNCT
cusj-10967	333	9	.	.	PUNCT
cusj-10967	334	1	[	[	X
cusj-10967	334	2	45	45	NUM
cusj-10967	334	3	]	]	PUNCT
cusj-10967	334	4	a.	a.	NOUN
cusj-10967	334	5	j.	j.	PROPN
cusj-10967	334	6	n.	n.	PROPN
cusj-10967	334	7	anelone	anelone	PROPN
cusj-10967	334	8	,	,	PUNCT
cusj-10967	334	9	m.	m.	PROPN
cusj-10967	334	10	f.	f.	PROPN
cusj-10967	334	11	villa	villa	PROPN
cusj-10967	334	12	-	-	PUNCT
cusj-10967	334	13	tamayo	tamayo	PROPN
cusj-10967	334	14	,	,	PUNCT
cusj-10967	334	15	p.	p.	PROPN
cusj-10967	334	16	s.	s.	PROPN
cusj-10967	334	17	rivadeneira	rivadeneira	PROPN
cusj-10967	334	18	,	,	PUNCT
cusj-10967	334	19	oncolytic	oncolytic	ADJ
cusj-10967	334	20	virus	virus	NOUN
cusj-10967	334	21	therapy	therapy	NOUN
cusj-10967	334	22	benefits	benefit	VERB
cusj-10967	334	23	from	from	ADP
cusj-10967	334	24	control	control	NOUN
cusj-10967	334	25	theory	theory	NOUN
cusj-10967	334	26	.	.	PUNCT
cusj-10967	335	1	r	r	NOUN
cusj-10967	335	2	soc	soc	NOUN
cusj-10967	335	3	open	open	VERB
cusj-10967	335	4	sci	sci	PROPN
cusj-10967	335	5	7	7	NUM
cusj-10967	335	6	,	,	PUNCT
cusj-10967	335	7	200473	200473	NUM
cusj-10967	335	8	(	(	PUNCT
cusj-10967	335	9	2020	2020	NUM
cusj-10967	335	10	)	)	PUNCT
cusj-10967	335	11	.	.	PUNCT
cusj-10967	336	1	[	[	X
cusj-10967	336	2	46	46	NUM
cusj-10967	336	3	]	]	PUNCT
cusj-10967	336	4	a.	a.	PROPN
cusj-10967	336	5	l.	l.	PROPN
cusj-10967	336	6	jenner	jenner	PROPN
cusj-10967	336	7	,	,	PUNCT
cusj-10967	336	8	f.	f.	PROPN
cusj-10967	336	9	frascoli	frascoli	PROPN
cusj-10967	336	10	,	,	PUNCT
cusj-10967	336	11	a.	a.	PROPN
cusj-10967	336	12	c.	c.	PROPN
cusj-10967	336	13	f.	f.	PROPN
cusj-10967	336	14	coster	coster	PROPN
cusj-10967	336	15	,	,	PUNCT
cusj-10967	336	16	p.	p.	PROPN
cusj-10967	336	17	s.	s.	PROPN
cusj-10967	336	18	kim	kim	PROPN
cusj-10967	336	19	,	,	PUNCT
cusj-10967	336	20	enhancing	enhance	VERB
cusj-10967	336	21	oncolytic	oncolytic	ADJ
cusj-10967	336	22	virotherapy	virotherapy	NOUN
cusj-10967	336	23	:	:	PUNCT
cusj-10967	336	24	observations	observation	NOUN
cusj-10967	336	25	from	from	ADP
cusj-10967	336	26	a	a	DET
cusj-10967	336	27	voronoi	voronoi	ADJ
cusj-10967	336	28	cell	cell	NOUN
cusj-10967	336	29	-	-	PUNCT
cusj-10967	336	30	based	base	VERB
cusj-10967	336	31	model	model	NOUN
cusj-10967	336	32	.	.	PUNCT
cusj-10967	337	1	j	j	PROPN
cusj-10967	337	2	theor	theor	PROPN
cusj-10967	337	3	biol	biol	PROPN
cusj-10967	337	4	485	485	NUM
cusj-10967	337	5	,	,	PUNCT
cusj-10967	337	6	110052	110052	NUM
cusj-10967	337	7	(	(	PUNCT
cusj-10967	337	8	2020	2020	NUM
cusj-10967	337	9	)	)	PUNCT
cusj-10967	337	10	.	.	PUNCT
cusj-10967	338	1	[	[	X
cusj-10967	338	2	47	47	NUM
cusj-10967	338	3	]	]	X
cusj-10967	338	4	f.	f.	PROPN
cusj-10967	338	5	hamdan	hamdan	PROPN
cusj-10967	338	6	et	et	PROPN
cusj-10967	338	7	al	al	PROPN
cusj-10967	338	8	.	.	PROPN
cusj-10967	338	9	,	,	PUNCT
cusj-10967	338	10	gamer	gamer	NOUN
cusj-10967	338	11	-	-	PUNCT
cusj-10967	338	12	ad	ad	NOUN
cusj-10967	338	13	:	:	PUNCT
cusj-10967	338	14	a	a	DET
cusj-10967	338	15	novel	novel	ADJ
cusj-10967	338	16	and	and	CCONJ
cusj-10967	338	17	rapid	rapid	ADJ
cusj-10967	338	18	method	method	NOUN
cusj-10967	338	19	for	for	ADP
cusj-10967	338	20	generating	generate	VERB
cusj-10967	338	21	recombinant	recombinant	ADJ
cusj-10967	338	22	adenoviruses	adenovirus	NOUN
cusj-10967	338	23	.	.	PUNCT
cusj-10967	339	1	mol	mol	ADP
cusj-10967	339	2	ther	ther	PROPN
cusj-10967	339	3	methods	method	NOUN
cusj-10967	339	4	clin	clin	PROPN
cusj-10967	339	5	dev	dev	PROPN
cusj-10967	339	6	20	20	NUM
cusj-10967	339	7	,	,	PUNCT
cusj-10967	339	8	625	625	NUM
cusj-10967	339	9	-	-	SYM
cusj-10967	339	10	634	634	NUM
cusj-10967	339	11	(	(	PUNCT
cusj-10967	339	12	2021	2021	NUM
cusj-10967	339	13	)	)	PUNCT
cusj-10967	339	14	.	.	PUNCT
cusj-10967	340	1	[	[	X
cusj-10967	340	2	48	48	NUM
cusj-10967	340	3	]	]	PUNCT
cusj-10967	340	4	l.	l.	PROPN
cusj-10967	340	5	e.	e.	PROPN
cusj-10967	340	6	torres	torres	PROPN
cusj-10967	340	7	-	-	PUNCT
cusj-10967	340	8	dominguez	dominguez	PROPN
cusj-10967	340	9	,	,	PUNCT
cusj-10967	340	10	a.	a.	PROPN
cusj-10967	340	11	l.	l.	PROPN
cusj-10967	340	12	de	de	X
cusj-10967	340	13	matos	matos	PROPN
cusj-10967	340	14	,	,	PUNCT
cusj-10967	340	15	m.	m.	NOUN
cusj-10967	340	16	m.	m.	PROPN
cusj-10967	340	17	rahman	rahman	PROPN
cusj-10967	340	18	,	,	PUNCT
cusj-10967	340	19	g.	g.	PROPN
cusj-10967	340	20	mcfadden	mcfadden	PROPN
cusj-10967	340	21	,	,	PUNCT
cusj-10967	340	22	methods	method	NOUN
cusj-10967	340	23	for	for	ADP
cusj-10967	340	24	the	the	DET
cusj-10967	340	25	construction	construction	NOUN
cusj-10967	340	26	of	of	ADP
cusj-10967	340	27	recombinant	recombinant	ADJ
cusj-10967	340	28	oncolytic	oncolytic	ADJ
cusj-10967	340	29	myxoma	myxoma	ADJ
cusj-10967	340	30	viruses	virus	NOUN
cusj-10967	340	31	.	.	PUNCT
cusj-10967	341	1	methods	method	NOUN
cusj-10967	341	2	mol	mol	ADP
cusj-10967	341	3	biol	biol	PROPN
cusj-10967	341	4	2225	2225	NUM
cusj-10967	341	5	,	,	PUNCT
cusj-10967	341	6	63	63	NUM
cusj-10967	341	7	-	-	SYM
cusj-10967	341	8	75	75	NUM
cusj-10967	341	9	(	(	PUNCT
cusj-10967	341	10	2021	2021	NUM
cusj-10967	341	11	)	)	PUNCT
cusj-10967	341	12	.	.	PUNCT
cusj-10967	342	1	[	[	X
cusj-10967	342	2	49	49	NUM
cusj-10967	342	3	]	]	PUNCT
cusj-10967	342	4	r.	r.	PROPN
cusj-10967	342	5	e.	e.	PROPN
cusj-10967	342	6	means	means	PROPN
cusj-10967	342	7	,	,	PUNCT
cusj-10967	342	8	s.	s.	PROPN
cusj-10967	342	9	g.	g.	PROPN
cusj-10967	342	10	roy	roy	PROPN
cusj-10967	342	11	,	,	PUNCT
cusj-10967	342	12	s.	s.	PROPN
cusj-10967	342	13	g.	g.	PROPN
cusj-10967	342	14	katz	katz	PROPN
cusj-10967	342	15	,	,	PUNCT
cusj-10967	342	16	the	the	DET
cusj-10967	342	17	propagation	propagation	NOUN
cusj-10967	342	18	and	and	CCONJ
cusj-10967	342	19	quantification	quantification	NOUN
cusj-10967	342	20	of	of	ADP
cusj-10967	342	21	two	two	NUM
cusj-10967	342	22	emerging	emerge	VERB
cusj-10967	342	23	oncolytic	oncolytic	ADJ
cusj-10967	342	24	viruses	virus	NOUN
cusj-10967	342	25	:	:	PUNCT
cusj-10967	342	26	vesicular	vesicular	ADJ
cusj-10967	342	27	stomatitis	stomatitis	NOUN
cusj-10967	342	28	(	(	PUNCT
cusj-10967	342	29	vsv	vsv	PROPN
cusj-10967	342	30	)	)	PUNCT
cusj-10967	342	31	and	and	CCONJ
cusj-10967	342	32	zika	zika	X
cusj-10967	342	33	(	(	PUNCT
cusj-10967	342	34	zikv	zikv	PROPN
cusj-10967	342	35	)	)	PUNCT
cusj-10967	342	36	.	.	PUNCT
cusj-10967	343	1	methods	method	NOUN
cusj-10967	343	2	mol	mol	ADP
cusj-10967	343	3	biol	biol	PROPN
cusj-10967	343	4	2097	2097	NUM
cusj-10967	343	5	,	,	PUNCT
cusj-10967	343	6	253	253	NUM
cusj-10967	343	7	-	-	SYM
cusj-10967	343	8	263	263	NUM
cusj-10967	343	9	(	(	PUNCT
cusj-10967	343	10	2020	2020	NUM
cusj-10967	343	11	)	)	PUNCT
cusj-10967	343	12	.	.	PUNCT
cusj-10967	344	1	[	[	X
cusj-10967	344	2	50	50	NUM
cusj-10967	344	3	]	]	X
cusj-10967	345	1	n.	n.	PROPN
cusj-10967	345	2	b.	b.	PROPN
cusj-10967	345	3	omar	omar	PROPN
cusj-10967	345	4	et	et	PROPN
cusj-10967	345	5	al	al	PROPN
cusj-10967	345	6	.	.	PROPN
cusj-10967	345	7	,	,	PUNCT
cusj-10967	345	8	safety	safety	NOUN
cusj-10967	345	9	and	and	CCONJ
cusj-10967	345	10	interim	interim	ADJ
cusj-10967	345	11	survival	survival	NOUN
cusj-10967	345	12	data	datum	NOUN
cusj-10967	345	13	after	after	ADP
cusj-10967	345	14	intracranial	intracranial	ADJ
cusj-10967	345	15	administration	administration	NOUN
cusj-10967	345	16	of	of	ADP
cusj-10967	345	17	m032	m032	PROPN
cusj-10967	345	18	,	,	PUNCT
cusj-10967	345	19	a	a	DET
cusj-10967	345	20	genetically	genetically	ADV
cusj-10967	345	21	engineered	engineer	VERB
cusj-10967	345	22	oncolytic	oncolytic	NOUN
cusj-10967	345	23	hsv-1	hsv-1	NOUN
cusj-10967	345	24	expressing	express	VERB
cusj-10967	345	25	il-12	il-12	NOUN
cusj-10967	345	26	,	,	PUNCT
cusj-10967	345	27	in	in	ADP
cusj-10967	345	28	pet	pet	ADJ
cusj-10967	345	29	dogs	dog	NOUN
cusj-10967	345	30	with	with	ADP
cusj-10967	345	31	sporadic	sporadic	ADJ
cusj-10967	345	32	gliomas	glioma	NOUN
cusj-10967	345	33	.	.	PUNCT
cusj-10967	346	1	neurosurg	neurosurg	ADJ
cusj-10967	346	2	focus	focus	VERB
cusj-10967	346	3	50	50	NUM
cusj-10967	346	4	,	,	PUNCT
cusj-10967	346	5	e5	e5	PROPN
cusj-10967	346	6	(	(	PUNCT
cusj-10967	346	7	2021	2021	NUM
cusj-10967	346	8	)	)	PUNCT
cusj-10967	346	9	.	.	PUNCT
cusj-10967	347	1	introduction	introduction	NOUN
cusj-10967	347	2	corresponding	correspond	VERB
cusj-10967	347	3	author	author	NOUN
cusj-10967	347	4	acknowledgements	acknowledgement	VERB
cusj-10967	347	5	the	the	DET
cusj-10967	347	6	author	author	NOUN
cusj-10967	347	7	expresses	express	VERB
cusj-10967	347	8	his	his	PRON
cusj-10967	347	9	gratitude	gratitude	NOUN
cusj-10967	347	10	to	to	ADP
cusj-10967	347	11	professor	professor	PROPN
cusj-10967	347	12	phoebe	phoebe	PROPN
cusj-10967	347	13	stewart	stewart	PROPN
cusj-10967	347	14	(	(	PUNCT
cusj-10967	347	15	department	department	PROPN
cusj-10967	347	16	of	of	ADP
cusj-10967	347	17	pharmacology	pharmacology	NOUN
cusj-10967	347	18	,	,	PUNCT
cusj-10967	347	19	case	case	NOUN
cusj-10967	347	20	western	western	PROPN
cusj-10967	347	21	reserve	reserve	PROPN
cusj-10967	347	22	university	university	PROPN
cusj-10967	347	23	school	school	NOUN
cusj-10967	347	24	of	of	ADP
cusj-10967	347	25	medicine	medicine	NOUN
cusj-10967	347	26	)	)	PUNCT
cusj-10967	347	27	for	for	ADP
cusj-10967	347	28	guidance	guidance	NOUN
cusj-10967	347	29	and	and	CCONJ
cusj-10967	347	30	feedback	feedback	NOUN
cusj-10967	347	31	in	in	ADP
cusj-10967	347	32	the	the	DET
cusj-10967	347	33	preparation	preparation	NOUN
cusj-10967	347	34	of	of	ADP
cusj-10967	347	35	the	the	DET
cusj-10967	347	36	article	article	NOUN
cusj-10967	347	37	.	.	PUNCT
cusj-10967	348	1	abbreviations	abbreviation	NOUN
cusj-10967	348	2	ov	ov	PROPN
cusj-10967	348	3	:	:	PUNCT
cusj-10967	348	4	oncolytic	oncolytic	ADJ
cusj-10967	348	5	virotherapy	virotherapy	PROPN
cusj-10967	348	6	hsv	hsv	PROPN
cusj-10967	348	7	:	:	PUNCT
cusj-10967	348	8	herpes	herpe	NOUN
cusj-10967	348	9	simplex	simplex	NOUN
cusj-10967	348	10	virus	virus	NOUN
cusj-10967	348	11	car	car	NOUN
cusj-10967	348	12	-	-	PUNCT
cusj-10967	348	13	t	t	NOUN
cusj-10967	348	14	:	:	PUNCT
cusj-10967	349	1	chimeric	chimeric	ADJ
cusj-10967	349	2	antigen	antigen	ADJ
cusj-10967	349	3	receptor	receptor	NOUN
cusj-10967	349	4	t	t	PROPN
cusj-10967	349	5	nk	nk	PROPN
cusj-10967	349	6	:	:	PUNCT
cusj-10967	349	7	natural	natural	ADJ
cusj-10967	349	8	killer	killer	NOUN
cusj-10967	349	9	t	t	PROPN
cusj-10967	349	10	-	-	PUNCT
cusj-10967	349	11	vec	vec	PROPN
cusj-10967	349	12	:	:	PUNCT
cusj-10967	349	13	talimogene	talimogene	PROPN
cusj-10967	349	14	laherparepvec	laherparepvec	PROPN
cusj-10967	349	15	trail	trail	NOUN
cusj-10967	349	16	:	:	PUNCT
cusj-10967	349	17	tumor	tumor	NOUN
cusj-10967	349	18	necrosis	necrosis	NOUN
cusj-10967	349	19	factor	factor	NOUN
cusj-10967	349	20	-	-	PUNCT
cusj-10967	349	21	related	relate	VERB
cusj-10967	349	22	apoptosis	apoptosis	NOUN
cusj-10967	349	23	-	-	PUNCT
cusj-10967	349	24	inducing	induce	VERB
cusj-10967	349	25	ligand	ligand	NOUN
cusj-10967	349	26	htert	htert	NOUN
cusj-10967	349	27	:	:	PUNCT
cusj-10967	349	28	human	human	ADJ
cusj-10967	349	29	telomerase	telomerase	NOUN
cusj-10967	349	30	reverse	reverse	VERB
cusj-10967	349	31	transcriptase	transcriptase	NOUN
cusj-10967	349	32	ccl5	ccl5	PROPN
cusj-10967	349	33	:	:	PUNCT
cusj-10967	349	34	chemokine	chemokine	PROPN
cusj-10967	349	35	ligand	ligand	NOUN
cusj-10967	349	36	5	5	NUM
cusj-10967	349	37	ccr5	ccr5	NOUN
cusj-10967	349	38	:	:	PUNCT
cusj-10967	349	39	chemokine	chemokine	ADJ
cusj-10967	349	40	receptor	receptor	NOUN
cusj-10967	349	41	type	type	NOUN
cusj-10967	349	42	5	5	NUM
cusj-10967	349	43	pd1	pd1	NOUN
cusj-10967	349	44	:	:	PUNCT
cusj-10967	349	45	programmed	program	VERB
cusj-10967	349	46	cell	cell	NOUN
cusj-10967	349	47	death	death	NOUN
cusj-10967	349	48	protein	protein	NOUN
cusj-10967	349	49	1	1	NUM
cusj-10967	349	50	pdac	pdac	NOUN
cusj-10967	349	51	:	:	PUNCT
cusj-10967	349	52	pancreatic	pancreatic	ADJ
cusj-10967	349	53	ductal	ductal	ADJ
cusj-10967	349	54	adenocarcinoma	adenocarcinoma	PROPN
cusj-10967	349	55	cd19	cd19	PROPN
cusj-10967	349	56	:	:	PUNCT
cusj-10967	349	57	b	b	X
cusj-10967	349	58	-	-	PUNCT
cusj-10967	349	59	lymphocyte	lymphocyte	ADJ
cusj-10967	349	60	antigen	antigen	NOUN
cusj-10967	349	61	cd19	cd19	PROPN
cusj-10967	349	62	references	reference	NOUN