id	sid	tid	token	lemma	pos
cusj-5637	1	1	columbia	columbia	PROPN
cusj-5637	1	2	undergraduate	undergraduate	PROPN
cusj-5637	1	3	science	science	PROPN
cusj-5637	1	4	journal	journal	PROPN
cusj-5637	1	5	open	open	ADJ
cusj-5637	1	6	-	-	PUNCT
cusj-5637	1	7	access	access	NOUN
cusj-5637	1	8	publication	publication	NOUN
cusj-5637	1	9	|	|	NOUN
cusj-5637	1	10	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5637	1	11	spring	spring	NOUN
cusj-5637	1	12	2014	2014	NUM
cusj-5637	2	1	|	|	ADV
cusj-5637	2	2	volume	volume	NOUN
cusj-5637	2	3	8	8	NUM
cusj-5637	2	4	4	4	NUM
cusj-5637	2	5	effect	effect	NOUN
cusj-5637	2	6	of	of	ADP
cusj-5637	2	7	fasudil	fasudil	NOUN
cusj-5637	2	8	on	on	ADP
cusj-5637	2	9	glioma	glioma	NOUN
cusj-5637	2	10	cell	cell	NOUN
cusj-5637	2	11	migration	migration	NOUN
cusj-5637	2	12	christine	christine	PROPN
cusj-5637	2	13	wang1	wang1	PROPN
cusj-5637	2	14	*	*	PROPN
cusj-5637	2	15	,	,	PUNCT
cusj-5637	2	16	athanassios	athanassio	NOUN
cusj-5637	2	17	dovas2	dovas2	ADJ
cusj-5637	2	18	,	,	PUNCT
cusj-5637	2	19	benjamin	benjamin	PROPN
cusj-5637	2	20	amendolara3	amendolara3	PROPN
cusj-5637	2	21	,	,	PUNCT
cusj-5637	2	22	peter	peter	PROPN
cusj-5637	2	23	canoll2	canoll2	VERB
cusj-5637	2	24	1columbia	1columbia	NUM
cusj-5637	2	25	college	college	NOUN
cusj-5637	2	26	,	,	PUNCT
cusj-5637	2	27	columbia	columbia	PROPN
cusj-5637	2	28	university	university	PROPN
cusj-5637	2	29	,	,	PUNCT
cusj-5637	2	30	new	new	PROPN
cusj-5637	2	31	york	york	PROPN
cusj-5637	2	32	,	,	PUNCT
cusj-5637	2	33	ny	ny	PROPN
cusj-5637	2	34	,	,	PUNCT
cusj-5637	2	35	usa	usa	PROPN
cusj-5637	2	36	;	;	PUNCT
cusj-5637	2	37	2department	2department	NUM
cusj-5637	2	38	of	of	ADP
cusj-5637	2	39	pathology	pathology	NOUN
cusj-5637	2	40	and	and	CCONJ
cusj-5637	2	41	cell	cell	NOUN
cusj-5637	2	42	biology	biology	NOUN
cusj-5637	2	43	,	,	PUNCT
cusj-5637	2	44	columbia	columbia	PROPN
cusj-5637	2	45	university	university	PROPN
cusj-5637	2	46	,	,	PUNCT
cusj-5637	2	47	new	new	PROPN
cusj-5637	2	48	york	york	PROPN
cusj-5637	2	49	,	,	PUNCT
cusj-5637	2	50	ny	ny	PROPN
cusj-5637	2	51	,	,	PUNCT
cusj-5637	2	52	usa	usa	PROPN
cusj-5637	2	53	;	;	PUNCT
cusj-5637	2	54	3department	3department	NUM
cusj-5637	2	55	of	of	ADP
cusj-5637	2	56	neurosurgery	neurosurgery	NOUN
cusj-5637	2	57	,	,	PUNCT
cusj-5637	2	58	columbia	columbia	PROPN
cusj-5637	2	59	university	university	PROPN
cusj-5637	2	60	,	,	PUNCT
cusj-5637	2	61	new	new	PROPN
cusj-5637	2	62	york	york	PROPN
cusj-5637	2	63	,	,	PUNCT
cusj-5637	2	64	ny	ny	PROPN
cusj-5637	2	65	,	,	PUNCT
cusj-5637	2	66	usa	usa	PROPN
cusj-5637	2	67	abstract	abstract	ADJ
cusj-5637	2	68	gliomas	glioma	NOUN
cusj-5637	2	69	are	be	AUX
cusj-5637	2	70	tumors	tumor	NOUN
cusj-5637	2	71	arising	arise	VERB
cusj-5637	2	72	from	from	ADP
cusj-5637	2	73	glial	glial	ADJ
cusj-5637	2	74	cells	cell	NOUN
cusj-5637	2	75	that	that	PRON
cusj-5637	2	76	are	be	AUX
cusj-5637	2	77	highly	highly	ADV
cusj-5637	2	78	infiltrative	infiltrative	ADJ
cusj-5637	2	79	within	within	ADP
cusj-5637	2	80	the	the	DET
cusj-5637	2	81	brain	brain	NOUN
cusj-5637	2	82	.	.	PUNCT
cusj-5637	3	1	their	their	PRON
cusj-5637	3	2	extensive	extensive	ADJ
cusj-5637	3	3	migratory	migratory	NOUN
cusj-5637	3	4	patterns	pattern	NOUN
cusj-5637	3	5	greatly	greatly	ADV
cusj-5637	3	6	limit	limit	VERB
cusj-5637	3	7	the	the	DET
cusj-5637	3	8	treatment	treatment	NOUN
cusj-5637	3	9	options	option	NOUN
cusj-5637	3	10	and	and	CCONJ
cusj-5637	3	11	prognoses	prognosis	NOUN
cusj-5637	3	12	for	for	ADP
cusj-5637	3	13	patients	patient	NOUN
cusj-5637	3	14	.	.	PUNCT
cusj-5637	4	1	it	it	PRON
cusj-5637	4	2	has	have	AUX
cusj-5637	4	3	been	be	AUX
cusj-5637	4	4	shown	show	VERB
cusj-5637	4	5	that	that	SCONJ
cusj-5637	4	6	glioma	glioma	NOUN
cusj-5637	4	7	cells	cell	NOUN
cusj-5637	4	8	undergo	undergo	VERB
cusj-5637	4	9	migration	migration	NOUN
cusj-5637	4	10	in	in	ADP
cusj-5637	4	11	a	a	DET
cusj-5637	4	12	unique	unique	ADJ
cusj-5637	4	13	manner	manner	NOUN
cusj-5637	4	14	that	that	PRON
cusj-5637	4	15	relies	rely	VERB
cusj-5637	4	16	heavily	heavily	ADV
cusj-5637	4	17	on	on	ADP
cusj-5637	4	18	non	non	ADJ
cusj-5637	4	19	-	-	ADJ
cusj-5637	4	20	muscle	muscle	ADJ
cusj-5637	4	21	myosin	myosin	PROPN
cusj-5637	4	22	ii	ii	PROPN
cusj-5637	4	23	.	.	PUNCT
cusj-5637	5	1	since	since	SCONJ
cusj-5637	5	2	functionality	functionality	NOUN
cusj-5637	5	3	of	of	ADP
cusj-5637	5	4	non	non	ADJ
cusj-5637	5	5	-	-	ADJ
cusj-5637	5	6	muscle	muscle	ADJ
cusj-5637	5	7	myosin	myosin	PROPN
cusj-5637	5	8	ii	ii	PROPN
cusj-5637	5	9	requires	require	VERB
cusj-5637	5	10	the	the	DET
cusj-5637	5	11	phosphorylation	phosphorylation	NOUN
cusj-5637	5	12	of	of	ADP
cusj-5637	5	13	its	its	PRON
cusj-5637	5	14	regulatory	regulatory	ADJ
cusj-5637	5	15	light	light	NOUN
cusj-5637	5	16	chain	chain	NOUN
cusj-5637	5	17	by	by	ADP
cusj-5637	5	18	enzymes	enzyme	NOUN
cusj-5637	5	19	like	like	ADP
cusj-5637	5	20	rho	rho	NOUN
cusj-5637	5	21	-	-	NOUN
cusj-5637	5	22	kinase	kinase	NOUN
cusj-5637	5	23	,	,	PUNCT
cusj-5637	5	24	we	we	PRON
cusj-5637	5	25	have	have	AUX
cusj-5637	5	26	treated	treat	VERB
cusj-5637	5	27	glioma	glioma	NOUN
cusj-5637	5	28	cells	cell	NOUN
cusj-5637	5	29	with	with	ADP
cusj-5637	5	30	the	the	DET
cusj-5637	5	31	rho	rho	ADJ
cusj-5637	5	32	-	-	PUNCT
cusj-5637	5	33	kinase	kinase	ADJ
cusj-5637	5	34	inhibitor	inhibitor	NOUN
cusj-5637	5	35	,	,	PUNCT
cusj-5637	5	36	fasudil	fasudil	NOUN
cusj-5637	5	37	,	,	PUNCT
cusj-5637	5	38	and	and	CCONJ
cusj-5637	5	39	tested	test	VERB
cusj-5637	5	40	its	its	PRON
cusj-5637	5	41	effects	effect	NOUN
cusj-5637	5	42	.	.	PUNCT
cusj-5637	6	1	the	the	DET
cusj-5637	6	2	results	result	NOUN
cusj-5637	6	3	indicated	indicate	VERB
cusj-5637	6	4	that	that	SCONJ
cusj-5637	6	5	fasudil	fasudil	NOUN
cusj-5637	6	6	is	be	AUX
cusj-5637	6	7	a	a	DET
cusj-5637	6	8	potent	potent	ADJ
cusj-5637	6	9	inhibitor	inhibitor	NOUN
cusj-5637	6	10	of	of	ADP
cusj-5637	6	11	migration	migration	NOUN
cusj-5637	6	12	and	and	CCONJ
cusj-5637	6	13	also	also	ADV
cusj-5637	6	14	accordingly	accordingly	ADV
cusj-5637	6	15	decreases	decrease	VERB
cusj-5637	6	16	regulatory	regulatory	ADJ
cusj-5637	6	17	light	light	NOUN
cusj-5637	6	18	chain	chain	NOUN
cusj-5637	6	19	phosphorylation	phosphorylation	NOUN
cusj-5637	6	20	in	in	ADP
cusj-5637	6	21	glioma	glioma	NOUN
cusj-5637	6	22	cells	cell	NOUN
cusj-5637	6	23	.	.	PUNCT
cusj-5637	7	1	this	this	PRON
cusj-5637	7	2	suggests	suggest	VERB
cusj-5637	7	3	that	that	SCONJ
cusj-5637	7	4	fasudil	fasudil	NOUN
cusj-5637	7	5	could	could	AUX
cusj-5637	7	6	be	be	AUX
cusj-5637	7	7	a	a	DET
cusj-5637	7	8	good	good	ADJ
cusj-5637	7	9	potentia	potentia	PROPN
cusj-5637	7	10	l	l	NOUN
cusj-5637	7	11	candidate	candidate	NOUN
cusj-5637	7	12	for	for	ADP
cusj-5637	7	13	future	future	NOUN
cusj-5637	7	14	in	in	ADP
cusj-5637	7	15	vivo	vivo	ADJ
cusj-5637	7	16	studies	study	NOUN
cusj-5637	7	17	and	and	CCONJ
cusj-5637	7	18	contribute	contribute	VERB
cusj-5637	7	19	to	to	ADP
cusj-5637	7	20	current	current	ADJ
cusj-5637	7	21	therapeutic	therapeutic	ADJ
cusj-5637	7	22	options	option	NOUN
cusj-5637	7	23	for	for	ADP
cusj-5637	7	24	the	the	DET
cusj-5637	7	25	treatment	treatment	NOUN
cusj-5637	7	26	of	of	ADP
cusj-5637	7	27	gliomas	glioma	NOUN
cusj-5637	7	28	.	.	PUNCT
cusj-5637	8	1	however	however	ADV
cusj-5637	8	2	,	,	PUNCT
cusj-5637	8	3	residual	residual	ADJ
cusj-5637	8	4	cell	cell	NOUN
cusj-5637	8	5	motility	motility	NOUN
cusj-5637	8	6	and	and	CCONJ
cusj-5637	8	7	phosphorylation	phosphorylation	NOUN
cusj-5637	8	8	despite	despite	SCONJ
cusj-5637	8	9	treatment	treatment	NOUN
cusj-5637	8	10	with	with	ADP
cusj-5637	8	11	fasudil	fasudil	NOUN
cusj-5637	8	12	also	also	ADV
cusj-5637	8	13	suggest	suggest	VERB
cusj-5637	8	14	that	that	SCONJ
cusj-5637	8	15	more	more	ADJ
cusj-5637	8	16	work	work	NOUN
cusj-5637	8	17	must	must	AUX
cusj-5637	8	18	be	be	AUX
cusj-5637	8	19	done	do	VERB
cusj-5637	8	20	to	to	PART
cusj-5637	8	21	assess	assess	VERB
cusj-5637	8	22	the	the	DET
cusj-5637	8	23	importance	importance	NOUN
cusj-5637	8	24	of	of	ADP
cusj-5637	8	25	other	other	ADJ
cusj-5637	8	26	pathways	pathway	NOUN
cusj-5637	8	27	in	in	ADP
cusj-5637	8	28	glioma	glioma	NOUN
cusj-5637	8	29	cell	cell	NOUN
cusj-5637	8	30	migration	migration	NOUN
cusj-5637	8	31	.	.	PUNCT
cusj-5637	9	1	introduction	introduction	NOUN
cusj-5637	9	2	gliomas	glioma	NOUN
cusj-5637	9	3	are	be	AUX
cusj-5637	9	4	brain	brain	NOUN
cusj-5637	9	5	tumors	tumor	NOUN
cusj-5637	9	6	that	that	PRON
cusj-5637	9	7	arise	arise	VERB
cusj-5637	9	8	from	from	ADP
cusj-5637	9	9	glial	glial	ADJ
cusj-5637	9	10	cells	cell	NOUN
cusj-5637	9	11	and	and	CCONJ
cusj-5637	9	12	malignant	malignant	ADJ
cusj-5637	9	13	gliomas	glioma	NOUN
cusj-5637	9	14	are	be	AUX
cusj-5637	9	15	associated	associate	VERB
cusj-5637	9	16	with	with	ADP
cusj-5637	9	17	poor	poor	ADJ
cusj-5637	9	18	prognoses	prognosis	NOUN
cusj-5637	9	19	due	due	ADP
cusj-5637	9	20	to	to	ADP
cusj-5637	9	21	their	their	PRON
cusj-5637	9	22	prolific	prolific	ADJ
cusj-5637	9	23	migration	migration	NOUN
cusj-5637	9	24	within	within	ADP
cusj-5637	9	25	the	the	DET
cusj-5637	9	26	brain	brain	NOUN
cusj-5637	10	1	[	[	X
cusj-5637	10	2	1	1	NUM
cusj-5637	10	3	]	]	PUNCT
cusj-5637	10	4	.	.	PUNCT
cusj-5637	11	1	though	though	SCONJ
cusj-5637	11	2	the	the	DET
cusj-5637	11	3	tumor	tumor	NOUN
cusj-5637	11	4	cells	cell	NOUN
cusj-5637	11	5	often	often	ADV
cusj-5637	11	6	do	do	AUX
cusj-5637	11	7	not	not	PART
cusj-5637	11	8	migrate	migrate	VERB
cusj-5637	11	9	outside	outside	ADV
cusj-5637	11	10	of	of	ADP
cusj-5637	11	11	the	the	DET
cusj-5637	11	12	central	central	ADJ
cusj-5637	11	13	nervous	nervous	ADJ
cusj-5637	11	14	system	system	NOUN
cusj-5637	11	15	,	,	PUNCT
cusj-5637	11	16	they	they	PRON
cusj-5637	11	17	spread	spread	VERB
cusj-5637	11	18	across	across	ADP
cusj-5637	11	19	white	white	ADJ
cusj-5637	11	20	matter	matter	NOUN
cusj-5637	11	21	tracts	tract	NOUN
cusj-5637	11	22	and	and	CCONJ
cusj-5637	11	23	are	be	AUX
cusj-5637	11	24	highly	highly	ADV
cusj-5637	11	25	infiltrative	infiltrative	ADJ
cusj-5637	11	26	[	[	X
cusj-5637	11	27	1	1	NUM
cusj-5637	11	28	]	]	PUNCT
cusj-5637	11	29	.	.	PUNCT
cusj-5637	12	1	in	in	ADP
cusj-5637	12	2	patients	patient	NOUN
cusj-5637	12	3	,	,	PUNCT
cusj-5637	12	4	this	this	DET
cusj-5637	12	5	extensive	extensive	ADJ
cusj-5637	12	6	migration	migration	NOUN
cusj-5637	12	7	makes	make	VERB
cusj-5637	12	8	it	it	PRON
cusj-5637	12	9	difficult	difficult	ADJ
cusj-5637	12	10	for	for	ADP
cusj-5637	12	11	a	a	DET
cusj-5637	12	12	complete	complete	ADJ
cusj-5637	12	13	surgical	surgical	ADJ
cusj-5637	12	14	tumor	tumor	NOUN
cusj-5637	12	15	resection	resection	NOUN
cusj-5637	12	16	,	,	PUNCT
cusj-5637	12	17	which	which	PRON
cusj-5637	12	18	can	can	AUX
cusj-5637	12	19	eventually	eventually	ADV
cusj-5637	12	20	cause	cause	VERB
cusj-5637	12	21	recurrent	recurrent	ADJ
cusj-5637	12	22	tumors	tumor	NOUN
cusj-5637	12	23	and	and	CCONJ
cusj-5637	12	24	disease	disease	NOUN
cusj-5637	12	25	progression	progression	NOUN
cusj-5637	12	26	[	[	X
cusj-5637	12	27	6	6	NUM
cusj-5637	12	28	]	]	PUNCT
cusj-5637	12	29	.	.	PUNCT
cusj-5637	13	1	this	this	PRON
cusj-5637	13	2	makes	make	VERB
cusj-5637	13	3	gliomas	glioma	NOUN
cusj-5637	13	4	particularly	particularly	ADV
cusj-5637	13	5	hard	hard	ADJ
cusj-5637	13	6	to	to	PART
cusj-5637	13	7	treat	treat	VERB
cusj-5637	13	8	and	and	CCONJ
cusj-5637	13	9	limits	limit	VERB
cusj-5637	13	10	available	available	ADJ
cusj-5637	13	11	therapeutic	therapeutic	ADJ
cusj-5637	13	12	options	option	NOUN
cusj-5637	13	13	[	[	X
cusj-5637	13	14	6	6	NUM
cusj-5637	13	15	]	]	PUNCT
cusj-5637	13	16	.	.	PUNCT
cusj-5637	14	1	glioma	glioma	NOUN
cusj-5637	14	2	cells	cell	NOUN
cusj-5637	14	3	exhibit	exhibit	VERB
cusj-5637	14	4	a	a	DET
cusj-5637	14	5	rather	rather	ADV
cusj-5637	14	6	unique	unique	ADJ
cusj-5637	14	7	migratory	migratory	NOUN
cusj-5637	14	8	pattern	pattern	NOUN
cusj-5637	14	9	due	due	ADP
cusj-5637	14	10	to	to	ADP
cusj-5637	14	11	the	the	PRON
cusj-5637	14	12	tightly	tightly	ADV
cusj-5637	14	13	packed	packed	ADJ
cusj-5637	14	14	and	and	CCONJ
cusj-5637	14	15	constraining	constrain	VERB
cusj-5637	14	16	physical	physical	ADJ
cusj-5637	14	17	environment	environment	NOUN
cusj-5637	14	18	they	they	PRON
cusj-5637	14	19	are	be	AUX
cusj-5637	14	20	exposed	expose	VERB
cusj-5637	14	21	to	to	ADP
cusj-5637	14	22	within	within	ADP
cusj-5637	14	23	the	the	DET
cusj-5637	14	24	brain	brain	NOUN
cusj-5637	14	25	parenchyma	parenchyma	NOUN
cusj-5637	14	26	which	which	PRON
cusj-5637	14	27	forces	force	VERB
cusj-5637	14	28	them	they	PRON
cusj-5637	14	29	to	to	PART
cusj-5637	14	30	migrate	migrate	VERB
cusj-5637	14	31	through	through	ADP
cusj-5637	14	32	sub	sub	ADJ
cusj-5637	14	33	-	-	ADJ
cusj-5637	14	34	micrometer	micrometer	NOUN
cusj-5637	14	35	spaces	space	NOUN
cusj-5637	14	36	[	[	X
cusj-5637	14	37	1	1	NUM
cusj-5637	14	38	]	]	PUNCT
cusj-5637	14	39	.	.	PUNCT
cusj-5637	15	1	consequently	consequently	ADV
cusj-5637	15	2	,	,	PUNCT
cusj-5637	15	3	cell	cell	NOUN
cusj-5637	15	4	migration	migration	NOUN
cusj-5637	15	5	occurs	occur	VERB
cusj-5637	15	6	in	in	ADP
cusj-5637	15	7	two	two	NUM
cusj-5637	15	8	steps	step	NOUN
cusj-5637	15	9	where	where	SCONJ
cusj-5637	15	10	the	the	DET
cusj-5637	15	11	cytoplasm	cytoplasm	ADJ
cusj-5637	15	12	first	first	ADJ
cusj-5637	15	13	protrudes	protrude	VERB
cusj-5637	15	14	outward	outward	ADV
cusj-5637	15	15	and	and	CCONJ
cusj-5637	15	16	the	the	DET
cusj-5637	15	17	cell	cell	NOUN
cusj-5637	15	18	body	body	NOUN
cusj-5637	15	19	follows	follow	VERB
cusj-5637	15	20	in	in	ADP
cusj-5637	15	21	saltatory	saltatory	ADJ
cusj-5637	15	22	fashion	fashion	NOUN
cusj-5637	15	23	[	[	X
cusj-5637	15	24	4	4	NUM
cusj-5637	15	25	]	]	PUNCT
cusj-5637	15	26	.	.	PUNCT
cusj-5637	16	1	interestingly	interestingly	ADV
cusj-5637	16	2	,	,	PUNCT
cusj-5637	16	3	this	this	DET
cusj-5637	16	4	type	type	NOUN
cusj-5637	16	5	of	of	ADP
cusj-5637	16	6	migration	migration	NOUN
cusj-5637	16	7	closely	closely	ADV
cusj-5637	16	8	resembles	resemble	VERB
cusj-5637	16	9	that	that	PRON
cusj-5637	16	10	of	of	ADP
cusj-5637	16	11	glial	glial	ADJ
cusj-5637	16	12	progenitors	progenitor	NOUN
cusj-5637	16	13	[	[	X
cusj-5637	16	14	4	4	NUM
cusj-5637	16	15	]	]	PUNCT
cusj-5637	16	16	.	.	PUNCT
cusj-5637	17	1	non	non	ADJ
cusj-5637	17	2	-	-	ADJ
cusj-5637	17	3	muscle	muscle	ADJ
cusj-5637	17	4	myosin	myosin	PROPN
cusj-5637	17	5	ii	ii	PROPN
cusj-5637	17	6	(	(	PUNCT
cusj-5637	17	7	nmii	nmii	NOUN
cusj-5637	17	8	)	)	PUNCT
cusj-5637	17	9	has	have	AUX
cusj-5637	17	10	been	be	AUX
cusj-5637	17	11	shown	show	VERB
cusj-5637	17	12	to	to	PART
cusj-5637	17	13	be	be	AUX
cusj-5637	17	14	particularly	particularly	ADV
cusj-5637	17	15	important	important	ADJ
cusj-5637	17	16	in	in	ADP
cusj-5637	17	17	glioma	glioma	NOUN
cusj-5637	17	18	cell	cell	NOUN
cusj-5637	17	19	migration	migration	NOUN
cusj-5637	17	20	and	and	CCONJ
cusj-5637	17	21	plays	play	VERB
cusj-5637	17	22	a	a	DET
cusj-5637	17	23	key	key	ADJ
cusj-5637	17	24	role	role	NOUN
cusj-5637	17	25	in	in	ADP
cusj-5637	17	26	the	the	DET
cusj-5637	17	27	second	second	ADJ
cusj-5637	17	28	step	step	NOUN
cusj-5637	17	29	,	,	PUNCT
cusj-5637	17	30	in	in	ADP
cusj-5637	17	31	which	which	PRON
cusj-5637	17	32	it	it	PRON
cusj-5637	17	33	forces	force	VERB
cusj-5637	17	34	the	the	DET
cusj-5637	17	35	large	large	ADJ
cusj-5637	17	36	nucleus	nucleus	NOUN
cusj-5637	17	37	and	and	CCONJ
cusj-5637	17	38	cell	cell	NOUN
cusj-5637	17	39	body	body	NOUN
cusj-5637	17	40	through	through	ADP
cusj-5637	17	41	small	small	ADJ
cusj-5637	17	42	spaces	space	NOUN
cusj-5637	17	43	within	within	ADP
cusj-5637	17	44	the	the	DET
cusj-5637	17	45	brain	brain	NOUN
cusj-5637	18	1	[	[	X
cusj-5637	18	2	1	1	NUM
cusj-5637	18	3	]	]	PUNCT
cusj-5637	18	4	.	.	PUNCT
cusj-5637	19	1	nmii	nmii	PROPN
cusj-5637	19	2	consists	consist	VERB
cusj-5637	19	3	of	of	ADP
cusj-5637	19	4	three	three	NUM
cusj-5637	19	5	distinct	distinct	ADJ
cusj-5637	19	6	isoforms	isoform	NOUN
cusj-5637	19	7	(	(	PUNCT
cusj-5637	19	8	a	a	DET
cusj-5637	19	9	,	,	PUNCT
cusj-5637	19	10	b	b	NOUN
cusj-5637	19	11	,	,	PUNCT
cusj-5637	19	12	c	c	NOUN
cusj-5637	19	13	)	)	PUNCT
cusj-5637	19	14	,	,	PUNCT
cusj-5637	19	15	defined	define	VERB
cusj-5637	19	16	by	by	ADP
cusj-5637	19	17	their	their	PRON
cusj-5637	19	18	heavy	heavy	ADJ
cusj-5637	19	19	chain	chain	NOUN
cusj-5637	19	20	,	,	PUNCT
cusj-5637	19	21	but	but	CCONJ
cusj-5637	19	22	only	only	ADV
cusj-5637	19	23	nmii	nmii	NOUN
cusj-5637	19	24	a	a	PRON
cusj-5637	19	25	and	and	CCONJ
cusj-5637	19	26	nmii	nmii	PROPN
cusj-5637	19	27	b	b	PROPN
cusj-5637	19	28	seem	seem	VERB
cusj-5637	19	29	to	to	PART
cusj-5637	19	30	be	be	AUX
cusj-5637	19	31	involved	involve	VERB
cusj-5637	19	32	in	in	ADP
cusj-5637	19	33	cell	cell	NOUN
cusj-5637	19	34	migration	migration	NOUN
cusj-5637	19	35	[	[	X
cusj-5637	19	36	13	13	NUM
cusj-5637	19	37	]	]	PUNCT
cusj-5637	19	38	.	.	PUNCT
cusj-5637	20	1	three	three	NUM
cusj-5637	20	2	distinct	distinct	ADJ
cusj-5637	20	3	genes	gene	NOUN
cusj-5637	20	4	encode	encode	VERB
cusj-5637	20	5	the	the	DET
cusj-5637	20	6	respective	respective	ADJ
cusj-5637	20	7	heavy	heavy	ADJ
cusj-5637	20	8	chains	chain	NOUN
cusj-5637	20	9	,	,	PUNCT
cusj-5637	20	10	and	and	CCONJ
cusj-5637	20	11	the	the	DET
cusj-5637	20	12	three	three	NUM
cusj-5637	20	13	isoforms	isoform	NOUN
cusj-5637	20	14	share	share	VERB
cusj-5637	20	15	6080	6080	NUM
cusj-5637	20	16	%	%	NOUN
cusj-5637	20	17	of	of	ADP
cusj-5637	20	18	the	the	DET
cusj-5637	20	19	same	same	ADJ
cusj-5637	20	20	amino	amino	NOUN
cusj-5637	20	21	acid	acid	NOUN
cusj-5637	20	22	sequence	sequence	NOUN
cusj-5637	20	23	identity	identity	NOUN
cusj-5637	20	24	[	[	X
cusj-5637	20	25	8	8	NUM
cusj-5637	20	26	]	]	PUNCT
cusj-5637	20	27	.	.	PUNCT
cusj-5637	21	1	all	all	DET
cusj-5637	21	2	nmii	nmii	NOUN
cusj-5637	21	3	molecules	molecule	NOUN
cusj-5637	21	4	have	have	VERB
cusj-5637	21	5	two	two	NUM
cusj-5637	21	6	globular	globular	ADJ
cusj-5637	21	7	heads	head	NOUN
cusj-5637	21	8	and	and	CCONJ
cusj-5637	21	9	a	a	DET
cusj-5637	21	10	helically	helically	ADV
cusj-5637	21	11	coiled	coil	VERB
cusj-5637	21	12	tail	tail	NOUN
cusj-5637	21	13	and	and	CCONJ
cusj-5637	21	14	assemble	assemble	VERB
cusj-5637	21	15	into	into	ADP
cusj-5637	21	16	bipolar	bipolar	ADJ
cusj-5637	21	17	filaments	filament	NOUN
cusj-5637	21	18	through	through	ADP
cusj-5637	21	19	interactions	interaction	NOUN
cusj-5637	21	20	between	between	ADP
cusj-5637	21	21	their	their	PRON
cusj-5637	21	22	coiled	coil	VERB
cusj-5637	21	23	-	-	PUNCT
cusj-5637	21	24	coil	coil	NOUN
cusj-5637	21	25	tails	tail	NOUN
cusj-5637	21	26	[	[	X
cusj-5637	21	27	11	11	NUM
cusj-5637	21	28	]	]	PUNCT
cusj-5637	21	29	.	.	PUNCT
cusj-5637	22	1	each	each	DET
cusj-5637	22	2	head	head	NOUN
cusj-5637	22	3	consists	consist	VERB
cusj-5637	22	4	of	of	ADP
cusj-5637	22	5	an	an	DET
cusj-5637	22	6	amino	amino	NOUN
cusj-5637	22	7	-	-	PUNCT
cusj-5637	22	8	terminal	terminal	ADJ
cusj-5637	22	9	portion	portion	NOUN
cusj-5637	22	10	of	of	ADP
cusj-5637	22	11	a	a	DET
cusj-5637	22	12	heavy	heavy	ADJ
cusj-5637	22	13	chain	chain	NOUN
cusj-5637	22	14	,	,	PUNCT
cusj-5637	22	15	one	one	NUM
cusj-5637	22	16	essential	essential	ADJ
cusj-5637	22	17	light	light	NOUN
cusj-5637	22	18	chain	chain	NOUN
cusj-5637	22	19	and	and	CCONJ
cusj-5637	22	20	one	one	NUM
cusj-5637	22	21	regulatory	regulatory	ADJ
cusj-5637	22	22	light	light	NOUN
cusj-5637	22	23	chain	chain	NOUN
cusj-5637	22	24	,	,	PUNCT
cusj-5637	22	25	and	and	CCONJ
cusj-5637	22	26	the	the	DET
cusj-5637	22	27	tail	tail	NOUN
cusj-5637	22	28	consists	consist	VERB
cusj-5637	22	29	of	of	ADP
cusj-5637	22	30	the	the	DET
cusj-5637	22	31	carboxyl	carboxyl	NOUN
cusj-5637	22	32	terminal	terminal	ADJ
cusj-5637	22	33	portions	portion	NOUN
cusj-5637	22	34	of	of	ADP
cusj-5637	22	35	the	the	DET
cusj-5637	22	36	two	two	NUM
cusj-5637	22	37	heavy	heavy	ADJ
cusj-5637	22	38	chains	chain	NOUN
cusj-5637	22	39	[	[	X
cusj-5637	22	40	11	11	NUM
cusj-5637	22	41	]	]	PUNCT
cusj-5637	22	42	.	.	PUNCT
cusj-5637	23	1	when	when	SCONJ
cusj-5637	23	2	nmii	nmii	NOUN
cusj-5637	23	3	regulatory	regulatory	ADJ
cusj-5637	23	4	light	light	NOUN
cusj-5637	23	5	chain	chain	NOUN
cusj-5637	23	6	(	(	PUNCT
cusj-5637	23	7	rlc	rlc	PROPN
cusj-5637	23	8	)	)	PUNCT
cusj-5637	23	9	is	be	AUX
cusj-5637	23	10	phosphorylated	phosphorylate	VERB
cusj-5637	23	11	,	,	PUNCT
cusj-5637	23	12	actin	actin	NOUN
cusj-5637	23	13	-	-	PUNCT
cusj-5637	23	14	dependent	dependent	ADJ
cusj-5637	23	15	mg2	mg2	PROPN
cusj-5637	23	16	+	+	NOUN
cusj-5637	23	17	-atpase	-atpase	NOUN
cusj-5637	23	18	motor	motor	NOUN
cusj-5637	23	19	activity	activity	NOUN
cusj-5637	23	20	that	that	PRON
cusj-5637	23	21	is	be	AUX
cusj-5637	23	22	associated	associate	VERB
cusj-5637	23	23	with	with	ADP
cusj-5637	23	24	the	the	DET
cusj-5637	23	25	globular	globular	ADJ
cusj-5637	23	26	head	head	NOUN
cusj-5637	23	27	domain	domain	NOUN
cusj-5637	23	28	increases	increase	NOUN
cusj-5637	23	29	.	.	PUNCT
cusj-5637	24	1	this	this	PRON
cusj-5637	24	2	induces	induce	VERB
cusj-5637	24	3	the	the	DET
cusj-5637	24	4	unidirectional	unidirectional	ADJ
cusj-5637	24	5	movement	movement	NOUN
cusj-5637	24	6	of	of	ADP
cusj-5637	24	7	the	the	DET
cusj-5637	24	8	motor	motor	NOUN
cusj-5637	24	9	domain	domain	NOUN
cusj-5637	24	10	on	on	ADP
cusj-5637	24	11	its	its	PRON
cusj-5637	24	12	associated	associated	ADJ
cusj-5637	24	13	actin	actin	NOUN
cusj-5637	24	14	filament	filament	NOUN
cusj-5637	24	15	resulting	result	VERB
cusj-5637	24	16	in	in	ADP
cusj-5637	24	17	actin	actin	NOUN
cusj-5637	24	18	filament	filament	NOUN
cusj-5637	24	19	contractility	contractility	NOUN
cusj-5637	24	20	[	[	X
cusj-5637	24	21	8	8	NUM
cusj-5637	24	22	,	,	PUNCT
cusj-5637	24	23	9	9	NUM
cusj-5637	24	24	]	]	PUNCT
cusj-5637	24	25	.	.	PUNCT
cusj-5637	25	1	though	though	SCONJ
cusj-5637	25	2	originally	originally	ADV
cusj-5637	25	3	it	it	PRON
cusj-5637	25	4	was	be	AUX
cusj-5637	25	5	thought	think	VERB
cusj-5637	25	6	that	that	SCONJ
cusj-5637	25	7	only	only	ADV
cusj-5637	25	8	the	the	DET
cusj-5637	25	9	ca2	ca2	PROPN
cusj-5637	25	10	+	+	PROPN
cusj-5637	25	11	-dependent	-dependent	ADJ
cusj-5637	25	12	myosin	myosin	NOUN
cusj-5637	25	13	light	light	NOUN
cusj-5637	25	14	chain	chain	PROPN
cusj-5637	25	15	kinase	kinase	PROPN
cusj-5637	25	16	(	(	PUNCT
cusj-5637	25	17	mlck	mlck	NOUN
cusj-5637	25	18	)	)	PUNCT
cusj-5637	25	19	phosphorylated	phosphorylate	VERB
cusj-5637	25	20	the	the	DET
cusj-5637	25	21	regulatory	regulatory	ADJ
cusj-5637	25	22	light	light	ADJ
cusj-5637	25	23	chains	chain	NOUN
cusj-5637	25	24	(	(	PUNCT
cusj-5637	25	25	rlcs	rlcs	NOUN
cusj-5637	25	26	)	)	PUNCT
cusj-5637	25	27	,	,	PUNCT
cusj-5637	25	28	it	it	PRON
cusj-5637	25	29	was	be	AUX
cusj-5637	25	30	later	later	ADV
cusj-5637	25	31	found	find	VERB
cusj-5637	25	32	that	that	SCONJ
cusj-5637	25	33	a	a	DET
cusj-5637	25	34	significant	significant	ADJ
cusj-5637	25	35	amount	amount	NOUN
cusj-5637	25	36	of	of	ADP
cusj-5637	25	37	rlc	rlc	PROPN
cusj-5637	25	38	phosphorylation	phosphorylation	PROPN
cusj-5637	25	39	occurs	occur	VERB
cusj-5637	25	40	through	through	ADP
cusj-5637	25	41	a	a	DET
cusj-5637	25	42	ca2	ca2	PROPN
cusj-5637	25	43	+	+	NOUN
cusj-5637	25	44	independent	independent	ADJ
cusj-5637	25	45	pathway	pathway	NOUN
cusj-5637	26	1	[	[	X
cusj-5637	26	2	5	5	NUM
cusj-5637	26	3	]	]	PUNCT
cusj-5637	26	4	.	.	PUNCT
cusj-5637	27	1	this	this	DET
cusj-5637	27	2	pathway	pathway	NOUN
cusj-5637	27	3	is	be	AUX
cusj-5637	27	4	now	now	ADV
cusj-5637	27	5	known	know	VERB
cusj-5637	27	6	to	to	PART
cusj-5637	27	7	be	be	AUX
cusj-5637	27	8	mediated	mediate	VERB
cusj-5637	27	9	by	by	ADP
cusj-5637	27	10	a	a	DET
cusj-5637	27	11	small	small	ADJ
cusj-5637	27	12	gtpase	gtpase	NOUN
cusj-5637	27	13	,	,	PUNCT
cusj-5637	27	14	rhoa	rhoa	PROPN
cusj-5637	27	15	,	,	PUNCT
cusj-5637	27	16	copyright	copyright	NOUN
cusj-5637	27	17	:	:	PUNCT
cusj-5637	27	18	©	©	PROPN
cusj-5637	27	19	2014	2014	NUM
cusj-5637	27	20	the	the	DET
cusj-5637	27	21	trustees	trustee	NOUN
cusj-5637	27	22	of	of	ADP
cusj-5637	27	23	columbia	columbia	PROPN
cusj-5637	27	24	university	university	PROPN
cusj-5637	27	25	,	,	PUNCT
cusj-5637	27	26	columbia	columbia	PROPN
cusj-5637	27	27	university	university	PROPN
cusj-5637	27	28	libraries	library	NOUN
cusj-5637	27	29	,	,	PUNCT
cusj-5637	27	30	some	some	DET
cusj-5637	27	31	rights	right	NOUN
cusj-5637	27	32	reserved	reserve	VERB
cusj-5637	27	33	,	,	PUNCT
cusj-5637	27	34	wang	wang	PROPN
cusj-5637	27	35	,	,	PUNCT
cusj-5637	27	36	et	et	PROPN
cusj-5637	27	37	al	al	PROPN
cusj-5637	27	38	.	.	PROPN
cusj-5637	27	39	received	receive	VERB
cusj-5637	27	40	1/1/2014	1/1/2014	PROPN
cusj-5637	27	41	.	.	PUNCT
cusj-5637	28	1	accepted	accept	VERB
cusj-5637	28	2	3/14/2014	3/14/2014	NUM
cusj-5637	28	3	.	.	PUNCT
cusj-5637	29	1	published	publish	VERB
cusj-5637	29	2	3/14/14	3/14/14	NUM
cusj-5637	29	3	.	.	PUNCT
cusj-5637	30	1	*	*	PUNCT
cusj-5637	30	2	to	to	PART
cusj-5637	30	3	whom	whom	PRON
cusj-5637	30	4	correspondence	correspondence	NOUN
cusj-5637	30	5	should	should	AUX
cusj-5637	30	6	be	be	AUX
cusj-5637	30	7	addressed	address	VERB
cusj-5637	30	8	:	:	PUNCT
cusj-5637	30	9	christine	christine	PROPN
cusj-5637	30	10	wang	wang	PROPN
cusj-5637	30	11	,	,	PUNCT
cusj-5637	30	12	columbia	columbia	PROPN
cusj-5637	30	13	university	university	PROPN
cusj-5637	30	14	,	,	PUNCT
cusj-5637	30	15	new	new	PROPN
cusj-5637	30	16	york	york	PROPN
cusj-5637	30	17	ny	ny	PROPN
cusj-5637	30	18	10027	10027	NUM
cusj-5637	30	19	,	,	PUNCT
cusj-5637	30	20	email	email	NOUN
cusj-5637	30	21	:	:	PUNCT
cusj-5637	30	22	cjw2146@columbia.edu	cjw2146@columbia.edu	PROPN
cusj-5637	30	23	.	.	PROPN
cusj-5637	30	24	biology	biology	PROPN
cusj-5637	30	25	columbia	columbia	PROPN
cusj-5637	30	26	undergraduate	undergraduate	PROPN
cusj-5637	30	27	science	science	PROPN
cusj-5637	30	28	journal	journal	PROPN
cusj-5637	30	29	open	open	ADJ
cusj-5637	30	30	-	-	PUNCT
cusj-5637	30	31	access	access	NOUN
cusj-5637	30	32	publication	publication	NOUN
cusj-5637	30	33	|	|	NOUN
cusj-5637	30	34	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5637	30	35	spring	spring	NOUN
cusj-5637	30	36	2014	2014	NUM
cusj-5637	31	1	|	|	ADV
cusj-5637	31	2	volume	volume	NOUN
cusj-5637	31	3	8	8	NUM
cusj-5637	31	4	5	5	NUM
cusj-5637	31	5	which	which	PRON
cusj-5637	31	6	had	have	AUX
cusj-5637	31	7	previously	previously	ADV
cusj-5637	31	8	been	be	AUX
cusj-5637	31	9	associated	associate	VERB
cusj-5637	31	10	with	with	ADP
cusj-5637	31	11	many	many	ADJ
cusj-5637	31	12	cellular	cellular	ADJ
cusj-5637	31	13	activities	activity	NOUN
cusj-5637	31	14	including	include	VERB
cusj-5637	31	15	cell	cell	NOUN
cusj-5637	31	16	motility	motility	NOUN
cusj-5637	31	17	,	,	PUNCT
cusj-5637	31	18	cytokinesis	cytokinesis	NOUN
cusj-5637	31	19	,	,	PUNCT
cusj-5637	31	20	regulation	regulation	NOUN
cusj-5637	31	21	of	of	ADP
cusj-5637	31	22	stress	stress	ADJ
cusj-5637	31	23	fibers	fiber	NOUN
cusj-5637	31	24	and	and	CCONJ
cusj-5637	31	25	formation	formation	NOUN
cusj-5637	31	26	of	of	ADP
cusj-5637	31	27	focal	focal	ADJ
cusj-5637	31	28	adhesions	adhesion	NOUN
cusj-5637	31	29	[	[	X
cusj-5637	31	30	5	5	NUM
cusj-5637	31	31	]	]	PUNCT
cusj-5637	31	32	.	.	PUNCT
cusj-5637	32	1	activated	activate	VERB
cusj-5637	32	2	gtprhoa	gtprhoa	NOUN
cusj-5637	32	3	can	can	AUX
cusj-5637	32	4	activate	activate	VERB
cusj-5637	32	5	rho	rho	ADJ
cusj-5637	32	6	-	-	ADJ
cusj-5637	32	7	associated	associate	VERB
cusj-5637	32	8	protein	protein	NOUN
cusj-5637	32	9	kinase	kinase	NOUN
cusj-5637	32	10	(	(	PUNCT
cusj-5637	32	11	rock	rock	PROPN
cusj-5637	32	12	)	)	PUNCT
cusj-5637	32	13	,	,	PUNCT
cusj-5637	32	14	which	which	PRON
cusj-5637	32	15	then	then	ADV
cusj-5637	32	16	phosphorylates	phosphorylate	VERB
cusj-5637	32	17	nmii	nmii	PROPN
cusj-5637	32	18	rlcs	rlcs	VERB
cusj-5637	32	19	directly	directly	ADV
cusj-5637	32	20	and	and	CCONJ
cusj-5637	32	21	also	also	ADV
cusj-5637	32	22	indirectly	indirectly	ADV
cusj-5637	32	23	by	by	ADP
cusj-5637	32	24	inactivating	inactivate	VERB
cusj-5637	32	25	myosin	myosin	NOUN
cusj-5637	32	26	phosphatase	phosphatase	NOUN
cusj-5637	32	27	[	[	X
cusj-5637	32	28	5	5	NUM
cusj-5637	32	29	]	]	PUNCT
cusj-5637	32	30	.	.	PUNCT
cusj-5637	33	1	both	both	PRON
cusj-5637	33	2	mlck	mlck	NOUN
cusj-5637	33	3	and	and	CCONJ
cusj-5637	33	4	rock	rock	NOUN
cusj-5637	33	5	can	can	AUX
cusj-5637	33	6	mono	mono	VERB
cusj-5637	33	7	-	-	PUNCT
cusj-5637	33	8	phosphorylate	phosphorylate	VERB
cusj-5637	33	9	the	the	DET
cusj-5637	33	10	serine	serine	NOUN
cusj-5637	33	11	19	19	NUM
cusj-5637	33	12	site	site	NOUN
cusj-5637	33	13	or	or	CCONJ
cusj-5637	33	14	diphosphorylate	diphosphorylate	VERB
cusj-5637	33	15	the	the	DET
cusj-5637	33	16	serine	serine	NOUN
cusj-5637	33	17	19	19	NUM
cusj-5637	33	18	and	and	CCONJ
cusj-5637	33	19	threonine	threonine	ADJ
cusj-5637	33	20	18	18	NUM
cusj-5637	33	21	sites	site	NOUN
cusj-5637	33	22	on	on	ADP
cusj-5637	33	23	the	the	DET
cusj-5637	33	24	rlc	rlc	PROPN
cusj-5637	34	1	[	[	X
cusj-5637	34	2	5	5	NUM
cusj-5637	34	3	]	]	PUNCT
cusj-5637	34	4	.	.	PUNCT
cusj-5637	35	1	regardless	regardless	ADV
cusj-5637	35	2	,	,	PUNCT
cusj-5637	35	3	previous	previous	ADJ
cusj-5637	35	4	studies	study	NOUN
cusj-5637	35	5	have	have	AUX
cusj-5637	35	6	demonstrated	demonstrate	VERB
cusj-5637	35	7	promising	promising	ADJ
cusj-5637	35	8	results	result	NOUN
cusj-5637	35	9	in	in	ADP
cusj-5637	35	10	which	which	DET
cusj-5637	35	11	inhibition	inhibition	NOUN
cusj-5637	35	12	of	of	ADP
cusj-5637	35	13	just	just	ADV
cusj-5637	35	14	rock	rock	NOUN
cusj-5637	35	15	can	can	AUX
cusj-5637	35	16	efficiently	efficiently	ADV
cusj-5637	35	17	inhibit	inhibit	VERB
cusj-5637	35	18	cell	cell	NOUN
cusj-5637	35	19	motility	motility	NOUN
cusj-5637	36	1	[	[	X
cusj-5637	36	2	1	1	NUM
cusj-5637	36	3	]	]	PUNCT
cusj-5637	36	4	.	.	PUNCT
cusj-5637	37	1	in	in	ADP
cusj-5637	37	2	the	the	DET
cusj-5637	37	3	beadle	beadle	PROPN
cusj-5637	37	4	et	et	PROPN
cusj-5637	37	5	al	al	PROPN
cusj-5637	37	6	.	.	PROPN
cusj-5637	37	7	study	study	PROPN
cusj-5637	37	8	,	,	PUNCT
cusj-5637	37	9	the	the	DET
cusj-5637	37	10	treatment	treatment	NOUN
cusj-5637	37	11	of	of	ADP
cusj-5637	37	12	cells	cell	NOUN
cusj-5637	37	13	with	with	ADP
cusj-5637	37	14	y-27632	y-27632	PROPN
cusj-5637	37	15	—	—	PUNCT
cusj-5637	37	16	a	a	DET
cusj-5637	37	17	potent	potent	ADJ
cusj-5637	37	18	inhibitor	inhibitor	NOUN
cusj-5637	37	19	of	of	ADP
cusj-5637	37	20	rock	rock	NOUN
cusj-5637	37	21	—	—	PUNCT
cusj-5637	37	22	proved	prove	VERB
cusj-5637	37	23	to	to	PART
cusj-5637	37	24	be	be	AUX
cusj-5637	37	25	an	an	DET
cusj-5637	37	26	efficient	efficient	ADJ
cusj-5637	37	27	inhibitor	inhibitor	NOUN
cusj-5637	37	28	of	of	ADP
cusj-5637	37	29	cell	cell	NOUN
cusj-5637	37	30	migration	migration	NOUN
cusj-5637	37	31	and	and	CCONJ
cusj-5637	37	32	motility	motility	NOUN
cusj-5637	37	33	.	.	PUNCT
cusj-5637	38	1	however	however	ADV
cusj-5637	38	2	,	,	PUNCT
cusj-5637	38	3	no	no	DET
cusj-5637	38	4	studies	study	NOUN
cusj-5637	38	5	have	have	AUX
cusj-5637	38	6	tested	test	VERB
cusj-5637	38	7	what	what	PRON
cusj-5637	38	8	the	the	DET
cusj-5637	38	9	effect	effect	NOUN
cusj-5637	38	10	of	of	ADP
cusj-5637	38	11	the	the	DET
cusj-5637	38	12	drug	drug	NOUN
cusj-5637	38	13	,	,	PUNCT
cusj-5637	38	14	fasudil	fasudil	NOUN
cusj-5637	38	15	,	,	PUNCT
cusj-5637	38	16	also	also	ADV
cusj-5637	38	17	a	a	DET
cusj-5637	38	18	rock	rock	NOUN
cusj-5637	38	19	inhibitor	inhibitor	NOUN
cusj-5637	38	20	,	,	PUNCT
cusj-5637	38	21	will	will	AUX
cusj-5637	38	22	have	have	VERB
cusj-5637	38	23	on	on	ADP
cusj-5637	38	24	glioma	glioma	NOUN
cusj-5637	38	25	cell	cell	NOUN
cusj-5637	38	26	migration	migration	NOUN
cusj-5637	38	27	.	.	PUNCT
cusj-5637	39	1	since	since	SCONJ
cusj-5637	39	2	fasudil	fasudil	NOUN
cusj-5637	39	3	is	be	AUX
cusj-5637	39	4	already	already	ADV
cusj-5637	39	5	an	an	DET
cusj-5637	39	6	fdaapproved	fdaapprove	VERB
cusj-5637	39	7	drug	drug	NOUN
cusj-5637	39	8	,	,	PUNCT
cusj-5637	39	9	it	it	PRON
cusj-5637	39	10	is	be	AUX
cusj-5637	39	11	valuable	valuable	ADJ
cusj-5637	39	12	to	to	PART
cusj-5637	39	13	evaluate	evaluate	VERB
cusj-5637	39	14	it	it	PRON
cusj-5637	39	15	further	far	ADV
cusj-5637	39	16	and	and	CCONJ
cusj-5637	39	17	determine	determine	VERB
cusj-5637	39	18	whether	whether	SCONJ
cusj-5637	39	19	or	or	CCONJ
cusj-5637	39	20	not	not	PART
cusj-5637	39	21	it	it	PRON
cusj-5637	39	22	has	have	VERB
cusj-5637	39	23	any	any	DET
cusj-5637	39	24	effect	effect	NOUN
cusj-5637	39	25	on	on	ADP
cusj-5637	39	26	migratory	migratory	ADJ
cusj-5637	39	27	patterns	pattern	NOUN
cusj-5637	39	28	.	.	PUNCT
cusj-5637	40	1	materials	material	NOUN
cusj-5637	40	2	and	and	CCONJ
cusj-5637	40	3	methods	method	NOUN
cusj-5637	40	4	cell	cell	NOUN
cusj-5637	40	5	culture	culture	NOUN
cusj-5637	40	6	mgpp3	mgpp3	PROPN
cusj-5637	40	7	(	(	PUNCT
cusj-5637	40	8	pdgf+/pten−/−/p53−/−	pdgf+/pten−/−/p53−/−	PROPN
cusj-5637	40	9	)	)	PUNCT
cusj-5637	40	10	and	and	CCONJ
cusj-5637	40	11	ptyb	ptyb	NOUN
cusj-5637	40	12	(	(	PUNCT
cusj-5637	40	13	ptenfl	ptenfl	PROPN
cusj-5637	40	14	/	/	SYM
cusj-5637	40	15	fl	fl	PROPN
cusj-5637	40	16	/	/	SYM
cusj-5637	40	17	yfp+	yfp+	PROPN
cusj-5637	40	18	)	)	PUNCT
cusj-5637	40	19	glioma	glioma	NOUN
cusj-5637	40	20	cells	cell	NOUN
cusj-5637	40	21	were	be	AUX
cusj-5637	40	22	used	use	VERB
cusj-5637	40	23	in	in	ADP
cusj-5637	40	24	this	this	DET
cusj-5637	40	25	study	study	NOUN
cusj-5637	40	26	.	.	PUNCT
cusj-5637	41	1	these	these	DET
cusj-5637	41	2	cells	cell	NOUN
cusj-5637	41	3	were	be	AUX
cusj-5637	41	4	isolated	isolate	VERB
cusj-5637	41	5	from	from	ADP
cusj-5637	41	6	gliomas	glioma	NOUN
cusj-5637	41	7	generated	generate	VERB
cusj-5637	41	8	in	in	ADP
cusj-5637	41	9	mice	mouse	NOUN
cusj-5637	41	10	[	[	X
cusj-5637	41	11	10	10	NUM
cusj-5637	41	12	]	]	PUNCT
cusj-5637	41	13	.	.	PUNCT
cusj-5637	42	1	cells	cell	NOUN
cusj-5637	42	2	were	be	AUX
cusj-5637	42	3	grown	grow	VERB
cusj-5637	42	4	in	in	ADP
cusj-5637	42	5	bfp	bfp	PROPN
cusj-5637	42	6	medium	medium	NOUN
cusj-5637	42	7	(	(	PUNCT
cusj-5637	42	8	dmem	dmem	VERB
cusj-5637	42	9	containing	contain	VERB
cusj-5637	42	10	2.5	2.5	NUM
cusj-5637	42	11	%	%	NOUN
cusj-5637	42	12	fbs	fbs	PROPN
cusj-5637	42	13	,	,	PUNCT
cusj-5637	42	14	n-2	n-2	NOUN
cusj-5637	42	15	supplement	supplement	NOUN
cusj-5637	42	16	,	,	PUNCT
cusj-5637	42	17	10	10	NUM
cusj-5637	42	18	ng	ng	NOUN
cusj-5637	42	19	/	/	SYM
cusj-5637	42	20	ml	ml	X
cusj-5637	42	21	fgf	fgf	PROPN
cusj-5637	42	22	,	,	PUNCT
cusj-5637	42	23	10	10	NUM
cusj-5637	42	24	ng	ng	NOUN
cusj-5637	42	25	/	/	SYM
cusj-5637	42	26	ml	ml	ADP
cusj-5637	42	27	pdgf	pdgf	ADJ
cusj-5637	42	28	-	-	PUNCT
cusj-5637	42	29	b	b	NOUN
cusj-5637	42	30	,	,	PUNCT
cusj-5637	42	31	and	and	CCONJ
cusj-5637	42	32	antimycotic	antimycotic	ADJ
cusj-5637	42	33	-	-	PUNCT
cusj-5637	42	34	antibiotic	antibiotic	ADJ
cusj-5637	42	35	supplement	supplement	NOUN
cusj-5637	42	36	)	)	PUNCT
cusj-5637	42	37	at	at	ADP
cusj-5637	42	38	37oc	37oc	NUM
cusj-5637	42	39	,	,	PUNCT
cusj-5637	42	40	5	5	NUM
cusj-5637	42	41	%	%	NOUN
cusj-5637	42	42	co2	co2	NOUN
cusj-5637	42	43	in	in	ADP
cusj-5637	42	44	a	a	DET
cusj-5637	42	45	humidified	humidified	ADJ
cusj-5637	42	46	atmosphere	atmosphere	NOUN
cusj-5637	42	47	.	.	PUNCT
cusj-5637	43	1	mtt	mtt	NOUN
cusj-5637	43	2	(	(	PUNCT
cusj-5637	43	3	3-(4,5	3-(4,5	PROPN
cusj-5637	43	4	-	-	PUNCT
cusj-5637	43	5	dimethylthiazol-2	dimethylthiazol-2	NUM
cusj-5637	43	6	-	-	PUNCT
cusj-5637	43	7	yl)-2,5diphenyltetrazolium	yl)-2,5diphenyltetrazolium	NOUN
cusj-5637	43	8	bromide	bromide	NOUN
cusj-5637	43	9	)	)	PUNCT
cusj-5637	43	10	assay	assay	VERB
cusj-5637	43	11	mgpp3	mgpp3	NOUN
cusj-5637	43	12	cells	cell	NOUN
cusj-5637	43	13	(	(	PUNCT
cusj-5637	43	14	1x103	1x103	NUM
cusj-5637	43	15	)	)	PUNCT
cusj-5637	43	16	in	in	ADP
cusj-5637	43	17	100	100	NUM
cusj-5637	43	18	μl	μl	PRON
cusj-5637	43	19	/	/	SYM
cusj-5637	43	20	well	well	INTJ
cusj-5637	43	21	were	be	AUX
cusj-5637	43	22	plated	plate	VERB
cusj-5637	43	23	in	in	ADP
cusj-5637	43	24	a	a	DET
cusj-5637	43	25	96	96	NUM
cusj-5637	43	26	-	-	PUNCT
cusj-5637	43	27	well	well	NOUN
cusj-5637	43	28	plate	plate	NOUN
cusj-5637	43	29	for	for	ADP
cusj-5637	43	30	12	12	NUM
cusj-5637	43	31	hours	hour	NOUN
cusj-5637	43	32	with	with	ADP
cusj-5637	43	33	3	3	NUM
cusj-5637	43	34	wells	well	NOUN
cusj-5637	43	35	dedicated	dedicate	VERB
cusj-5637	43	36	to	to	ADP
cusj-5637	43	37	each	each	PRON
cusj-5637	43	38	of	of	ADP
cusj-5637	43	39	the	the	DET
cusj-5637	43	40	13	13	NUM
cusj-5637	43	41	treatment	treatment	NOUN
cusj-5637	43	42	conditions	condition	NOUN
cusj-5637	43	43	.	.	PUNCT
cusj-5637	44	1	treatment	treatment	NOUN
cusj-5637	44	2	conditions	condition	NOUN
cusj-5637	44	3	included	include	VERB
cusj-5637	44	4	no	no	DET
cusj-5637	44	5	drug	drug	NOUN
cusj-5637	44	6	and	and	CCONJ
cusj-5637	44	7	the	the	DET
cusj-5637	44	8	indicated	indicate	VERB
cusj-5637	44	9	concentrations	concentration	NOUN
cusj-5637	44	10	of	of	ADP
cusj-5637	44	11	either	either	CCONJ
cusj-5637	44	12	fasudil	fasudil	NOUN
cusj-5637	44	13	or	or	CCONJ
cusj-5637	44	14	y27632	y27632	PROPN
cusj-5637	44	15	.	.	PROPN
cusj-5637	44	16	20	20	NUM
cusj-5637	44	17	μl	μl	ADP
cusj-5637	44	18	of	of	ADP
cusj-5637	44	19	reagent	reagent	NOUN
cusj-5637	44	20	(	(	PUNCT
cusj-5637	44	21	celltiter	celltiter	NOUN
cusj-5637	44	22	96	96	NUM
cusj-5637	44	23	aqueous	aqueous	ADJ
cusj-5637	44	24	one	one	NUM
cusj-5637	44	25	solution	solution	NOUN
cusj-5637	44	26	reagent	reagent	NOUN
cusj-5637	44	27	)	)	PUNCT
cusj-5637	44	28	was	be	AUX
cusj-5637	44	29	added	add	VERB
cusj-5637	44	30	to	to	ADP
cusj-5637	44	31	each	each	DET
cusj-5637	44	32	well	well	ADV
cusj-5637	44	33	and	and	CCONJ
cusj-5637	44	34	the	the	DET
cusj-5637	44	35	plate	plate	NOUN
cusj-5637	44	36	was	be	AUX
cusj-5637	44	37	incubated	incubate	VERB
cusj-5637	44	38	for	for	ADP
cusj-5637	44	39	6	6	NUM
cusj-5637	44	40	hours	hour	NOUN
cusj-5637	44	41	with	with	ADP
cusj-5637	44	42	reagent	reagent	NOUN
cusj-5637	44	43	.	.	PUNCT
cusj-5637	45	1	the	the	DET
cusj-5637	45	2	reagent	reagent	NOUN
cusj-5637	45	3	of	of	ADP
cusj-5637	45	4	the	the	DET
cusj-5637	45	5	assay	assay	NOUN
cusj-5637	45	6	is	be	AUX
cusj-5637	45	7	a	a	DET
cusj-5637	45	8	yellow	yellow	ADJ
cusj-5637	45	9	tetrazole	tetrazole	NOUN
cusj-5637	45	10	that	that	PRON
cusj-5637	45	11	is	be	AUX
cusj-5637	45	12	reduced	reduce	VERB
cusj-5637	45	13	to	to	ADP
cusj-5637	45	14	purple	purple	ADJ
cusj-5637	45	15	formazan	formazan	NOUN
cusj-5637	45	16	in	in	ADP
cusj-5637	45	17	living	living	NOUN
cusj-5637	45	18	cells	cell	NOUN
cusj-5637	45	19	[	[	X
cusj-5637	45	20	12	12	NUM
cusj-5637	45	21	]	]	PUNCT
cusj-5637	45	22	.	.	PUNCT
cusj-5637	46	1	consequently	consequently	ADV
cusj-5637	46	2	,	,	PUNCT
cusj-5637	46	3	wells	well	NOUN
cusj-5637	46	4	that	that	PRON
cusj-5637	46	5	appeared	appear	VERB
cusj-5637	46	6	more	more	ADV
cusj-5637	46	7	purple	purple	ADJ
cusj-5637	46	8	in	in	ADP
cusj-5637	46	9	hue	hue	NOUN
cusj-5637	46	10	contained	contain	VERB
cusj-5637	46	11	more	more	ADV
cusj-5637	46	12	viable	viable	ADJ
cusj-5637	46	13	cells	cell	NOUN
cusj-5637	46	14	.	.	PUNCT
cusj-5637	47	1	absorbances	absorbance	NOUN
cusj-5637	47	2	were	be	AUX
cusj-5637	47	3	recorded	record	VERB
cusj-5637	47	4	at	at	ADP
cusj-5637	47	5	490	490	NUM
cusj-5637	47	6	nm	nm	NOUN
cusj-5637	47	7	using	use	VERB
cusj-5637	47	8	a	a	DET
cusj-5637	47	9	96	96	NUM
cusj-5637	47	10	-	-	PUNCT
cusj-5637	47	11	well	well	NOUN
cusj-5637	47	12	plate	plate	NOUN
cusj-5637	47	13	reader	reader	NOUN
cusj-5637	47	14	.	.	PUNCT
cusj-5637	48	1	transwell	transwell	NOUN
cusj-5637	48	2	migration	migration	NOUN
cusj-5637	48	3	assay	assay	VERB
cusj-5637	48	4	mgpp3	mgpp3	NOUN
cusj-5637	48	5	cells	cell	NOUN
cusj-5637	48	6	(	(	PUNCT
cusj-5637	48	7	1x105	1x105	NOUN
cusj-5637	48	8	)	)	PUNCT
cusj-5637	48	9	in	in	ADP
cusj-5637	48	10	a	a	DET
cusj-5637	48	11	total	total	ADJ
cusj-5637	48	12	volume	volume	NOUN
cusj-5637	48	13	of	of	ADP
cusj-5637	48	14	200	200	NUM
cusj-5637	48	15	μl	μl	DET
cusj-5637	48	16	10	10	NUM
cusj-5637	48	17	%	%	NOUN
cusj-5637	48	18	fetal	fetal	ADJ
cusj-5637	48	19	bovine	bovine	NOUN
cusj-5637	48	20	serum	serum	NOUN
cusj-5637	48	21	(	(	PUNCT
cusj-5637	48	22	fbs	fbs	PROPN
cusj-5637	48	23	)	)	PUNCT
cusj-5637	48	24	were	be	AUX
cusj-5637	48	25	seeded	seed	VERB
cusj-5637	48	26	on	on	ADP
cusj-5637	48	27	top	top	NOUN
cusj-5637	48	28	of	of	ADP
cusj-5637	48	29	3	3	NUM
cusj-5637	48	30	μm	μm	NOUN
cusj-5637	48	31	fluoroblok	fluoroblok	NOUN
cusj-5637	48	32	transfilters	transfilter	NOUN
cusj-5637	48	33	(	(	PUNCT
cusj-5637	48	34	bd	bd	PROPN
cusj-5637	48	35	biosciences	bioscience	NOUN
cusj-5637	48	36	,	,	PUNCT
cusj-5637	48	37	san	san	PROPN
cusj-5637	48	38	jose	jose	PROPN
cusj-5637	48	39	,	,	PUNCT
cusj-5637	48	40	ca	ca	NOUN
cusj-5637	48	41	)	)	PUNCT
cusj-5637	48	42	.	.	PUNCT
cusj-5637	49	1	500	500	NUM
cusj-5637	49	2	μl	μl	NOUN
cusj-5637	49	3	of	of	ADP
cusj-5637	49	4	10	10	NUM
cusj-5637	49	5	%	%	NOUN
cusj-5637	49	6	fbs	fbs	PROPN
cusj-5637	49	7	was	be	AUX
cusj-5637	49	8	added	add	VERB
cusj-5637	49	9	to	to	ADP
cusj-5637	49	10	the	the	DET
cusj-5637	49	11	bottom	bottom	NOUN
cusj-5637	49	12	well	well	ADV
cusj-5637	49	13	.	.	PUNCT
cusj-5637	50	1	a	a	DET
cusj-5637	50	2	plate	plate	NOUN
cusj-5637	50	3	was	be	AUX
cusj-5637	50	4	set	set	VERB
cusj-5637	50	5	up	up	ADP
cusj-5637	50	6	with	with	ADP
cusj-5637	50	7	three	three	NUM
cusj-5637	50	8	transfilters	transfilter	NOUN
cusj-5637	50	9	per	per	ADP
cusj-5637	50	10	condition	condition	NOUN
cusj-5637	50	11	—	—	PUNCT
cusj-5637	50	12	control	control	NOUN
cusj-5637	50	13	,	,	PUNCT
cusj-5637	50	14	100	100	NUM
cusj-5637	50	15	μm	μm	NUM
cusj-5637	50	16	fasudil	fasudil	NOUN
cusj-5637	50	17	and	and	CCONJ
cusj-5637	50	18	500	500	NUM
cusj-5637	50	19	μm	μm	NOUN
cusj-5637	50	20	y-27632	y-27632	INTJ
cusj-5637	50	21	.	.	PUNCT
cusj-5637	51	1	for	for	ADP
cusj-5637	51	2	conditions	condition	NOUN
cusj-5637	51	3	that	that	PRON
cusj-5637	51	4	require	require	VERB
cusj-5637	51	5	drug	drug	NOUN
cusj-5637	51	6	treatment	treatment	NOUN
cusj-5637	51	7	,	,	PUNCT
cusj-5637	51	8	drug	drug	NOUN
cusj-5637	51	9	was	be	AUX
cusj-5637	51	10	added	add	VERB
cusj-5637	51	11	both	both	CCONJ
cusj-5637	51	12	above	above	ADP
cusj-5637	51	13	and	and	CCONJ
cusj-5637	51	14	below	below	ADP
cusj-5637	51	15	the	the	DET
cusj-5637	51	16	transfilter	transfilter	NOUN
cusj-5637	51	17	membrane	membrane	NOUN
cusj-5637	51	18	.	.	PUNCT
cusj-5637	52	1	the	the	DET
cusj-5637	52	2	entire	entire	ADJ
cusj-5637	52	3	plate	plate	NOUN
cusj-5637	52	4	containing	contain	VERB
cusj-5637	52	5	all	all	DET
cusj-5637	52	6	transfilters	transfilter	NOUN
cusj-5637	52	7	was	be	AUX
cusj-5637	52	8	incubated	incubate	VERB
cusj-5637	52	9	for	for	ADP
cusj-5637	52	10	6	6	NUM
cusj-5637	52	11	hours	hour	NOUN
cusj-5637	52	12	at	at	ADP
cusj-5637	52	13	37	37	NUM
cusj-5637	52	14	°	°	NOUN
cusj-5637	52	15	c	c	NOUN
cusj-5637	52	16	.	.	PUNCT
cusj-5637	53	1	after	after	ADP
cusj-5637	53	2	incubation	incubation	NOUN
cusj-5637	53	3	,	,	PUNCT
cusj-5637	53	4	both	both	DET
cusj-5637	53	5	sides	side	NOUN
cusj-5637	53	6	of	of	ADP
cusj-5637	53	7	the	the	DET
cusj-5637	53	8	transfilter	transfilter	NOUN
cusj-5637	53	9	were	be	AUX
cusj-5637	53	10	washed	wash	VERB
cusj-5637	53	11	three	three	NUM
cusj-5637	53	12	times	time	NOUN
cusj-5637	53	13	with	with	ADP
cusj-5637	53	14	phosphate	phosphate	NOUN
cusj-5637	53	15	-	-	PUNCT
cusj-5637	53	16	buffered	buffer	VERB
cusj-5637	53	17	saline	saline	NOUN
cusj-5637	53	18	(	(	PUNCT
cusj-5637	53	19	pbs	pbs	PROPN
cusj-5637	53	20	)	)	PUNCT
cusj-5637	53	21	.	.	PUNCT
cusj-5637	54	1	cells	cell	NOUN
cusj-5637	54	2	were	be	AUX
cusj-5637	54	3	then	then	ADV
cusj-5637	54	4	fixed	fix	VERB
cusj-5637	54	5	with	with	ADP
cusj-5637	54	6	4	4	NUM
cusj-5637	54	7	%	%	NOUN
cusj-5637	54	8	paraformaldehyde	paraformaldehyde	NOUN
cusj-5637	54	9	for	for	ADP
cusj-5637	54	10	15	15	NUM
cusj-5637	54	11	minutes	minute	NOUN
cusj-5637	54	12	on	on	ADP
cusj-5637	54	13	ice	ice	NOUN
cusj-5637	54	14	.	.	PUNCT
cusj-5637	55	1	after	after	ADP
cusj-5637	55	2	another	another	DET
cusj-5637	55	3	three	three	NUM
cusj-5637	55	4	washes	wash	NOUN
cusj-5637	55	5	in	in	ADP
cusj-5637	55	6	pbs	pbs	PROPN
cusj-5637	55	7	,	,	PUNCT
cusj-5637	55	8	cells	cell	NOUN
cusj-5637	55	9	were	be	AUX
cusj-5637	55	10	stained	stain	VERB
cusj-5637	55	11	with	with	ADP
cusj-5637	55	12	4,6	4,6	NOUN
cusj-5637	55	13	-	-	PUNCT
cusj-5637	55	14	diamidino-2phenylindole	diamidino-2phenylindole	ADJ
cusj-5637	55	15	(	(	PUNCT
cusj-5637	55	16	dapi	dapi	NOUN
cusj-5637	55	17	)	)	PUNCT
cusj-5637	55	18	for	for	ADP
cusj-5637	55	19	20	20	NUM
cusj-5637	55	20	minutes	minute	NOUN
cusj-5637	55	21	.	.	PUNCT
cusj-5637	56	1	the	the	DET
cusj-5637	56	2	transfilter	transfilter	NOUN
cusj-5637	56	3	membranes	membrane	NOUN
cusj-5637	56	4	were	be	AUX
cusj-5637	56	5	removed	remove	VERB
cusj-5637	56	6	and	and	CCONJ
cusj-5637	56	7	mounted	mount	VERB
cusj-5637	56	8	on	on	ADP
cusj-5637	56	9	slides	slide	NOUN
cusj-5637	56	10	.	.	PUNCT
cusj-5637	57	1	images	image	NOUN
cusj-5637	57	2	of	of	ADP
cusj-5637	57	3	the	the	DET
cusj-5637	57	4	bottom	bottom	ADJ
cusj-5637	57	5	part	part	NOUN
cusj-5637	57	6	of	of	ADP
cusj-5637	57	7	the	the	DET
cusj-5637	57	8	filters	filter	NOUN
cusj-5637	57	9	were	be	AUX
cusj-5637	57	10	acquired	acquire	VERB
cusj-5637	57	11	on	on	ADP
cusj-5637	57	12	a	a	DET
cusj-5637	57	13	nikon	nikon	PROPN
cusj-5637	57	14	widefield	widefield	NOUN
cusj-5637	57	15	-	-	PUNCT
cusj-5637	57	16	inverted	invert	VERB
cusj-5637	57	17	microscope	microscope	NOUN
cusj-5637	57	18	using	use	VERB
cusj-5637	57	19	a	a	DET
cusj-5637	57	20	4×	4×	NOUN
cusj-5637	57	21	objective	objective	NOUN
cusj-5637	57	22	and	and	CCONJ
cusj-5637	57	23	the	the	DET
cusj-5637	57	24	nuclei	nucleus	NOUN
cusj-5637	57	25	within	within	ADP
cusj-5637	57	26	five	five	NUM
cusj-5637	57	27	fields	field	NOUN
cusj-5637	57	28	per	per	ADP
cusj-5637	57	29	membrane	membrane	NOUN
cusj-5637	57	30	were	be	AUX
cusj-5637	57	31	counted	count	VERB
cusj-5637	57	32	and	and	CCONJ
cusj-5637	57	33	averaged	average	VERB
cusj-5637	57	34	together	together	ADV
cusj-5637	57	35	.	.	PUNCT
cusj-5637	58	1	phosphomyosin	phosphomyosin	VERB
cusj-5637	58	2	staining	stain	VERB
cusj-5637	58	3	ptyb	ptyb	NOUN
cusj-5637	58	4	cells	cell	NOUN
cusj-5637	58	5	(	(	PUNCT
cusj-5637	58	6	3.4x104	3.4x104	NOUN
cusj-5637	58	7	)	)	PUNCT
cusj-5637	58	8	were	be	AUX
cusj-5637	58	9	plated	plate	VERB
cusj-5637	58	10	on	on	ADP
cusj-5637	58	11	polyl	polyl	NOUN
cusj-5637	58	12	-	-	PUNCT
cusj-5637	58	13	lysine	lysine	NOUN
cusj-5637	58	14	coated	coat	VERB
cusj-5637	58	15	coverslips	coverslip	NOUN
cusj-5637	58	16	overnight	overnight	ADV
cusj-5637	58	17	.	.	PUNCT
cusj-5637	59	1	cells	cell	NOUN
cusj-5637	59	2	were	be	AUX
cusj-5637	59	3	then	then	ADV
cusj-5637	59	4	treated	treat	VERB
cusj-5637	59	5	with	with	ADP
cusj-5637	59	6	either	either	CCONJ
cusj-5637	59	7	fresh	fresh	ADJ
cusj-5637	59	8	bfp	bfp	NOUN
cusj-5637	59	9	media	medium	NOUN
cusj-5637	59	10	,	,	PUNCT
cusj-5637	59	11	bfp	bfp	PROPN
cusj-5637	59	12	supplemented	supplement	VERB
cusj-5637	59	13	with	with	ADP
cusj-5637	59	14	60	60	NUM
cusj-5637	59	15	μm	μm	NUM
cusj-5637	59	16	fasudil	fasudil	NOUN
cusj-5637	59	17	,	,	PUNCT
cusj-5637	59	18	or	or	CCONJ
cusj-5637	59	19	bfp	bfp	NOUN
cusj-5637	59	20	supplemented	supplement	VERB
cusj-5637	59	21	with	with	ADP
cusj-5637	59	22	50	50	NUM
cusj-5637	59	23	μm	μm	NOUN
cusj-5637	59	24	y-27632	y-27632	PROPN
cusj-5637	59	25	for	for	ADP
cusj-5637	59	26	three	three	NUM
cusj-5637	59	27	hours	hour	NOUN
cusj-5637	59	28	.	.	PUNCT
cusj-5637	60	1	cells	cell	NOUN
cusj-5637	60	2	were	be	AUX
cusj-5637	60	3	fixed	fix	VERB
cusj-5637	60	4	with	with	ADP
cusj-5637	60	5	4	4	NUM
cusj-5637	60	6	%	%	NOUN
cusj-5637	60	7	pfa	pfa	NOUN
cusj-5637	60	8	and	and	CCONJ
cusj-5637	60	9	stained	stain	VERB
cusj-5637	60	10	overnight	overnight	ADV
cusj-5637	60	11	at	at	ADP
cusj-5637	60	12	4	4	NUM
cusj-5637	60	13	°	°	ADP
cusj-5637	60	14	c	c	NOUN
cusj-5637	60	15	with	with	ADP
cusj-5637	60	16	phospho	phospho	ADJ
cusj-5637	60	17	-	-	PUNCT
cusj-5637	60	18	serine	serine	ADJ
cusj-5637	60	19	19	19	NUM
cusj-5637	60	20	antibody	antibody	NOUN
cusj-5637	60	21	(	(	PUNCT
cusj-5637	60	22	ps19	ps19	PROPN
cusj-5637	60	23	,	,	PUNCT
cusj-5637	60	24	mouse	mouse	NOUN
cusj-5637	60	25	antibody	antibody	NOUN
cusj-5637	60	26	;	;	PUNCT
cusj-5637	60	27	cell	cell	NOUN
cusj-5637	60	28	signaling	signal	VERB
cusj-5637	60	29	technology	technology	NOUN
cusj-5637	60	30	)	)	PUNCT
cusj-5637	60	31	or	or	CCONJ
cusj-5637	60	32	phosphor	phosphor	NOUN
cusj-5637	60	33	-	-	ADJ
cusj-5637	60	34	threonine	threonine	ADJ
cusj-5637	60	35	18	18	NUM
cusj-5637	60	36	-	-	PUNCT
cusj-5637	60	37	serine	serine	NOUN
cusj-5637	60	38	19	19	NUM
cusj-5637	60	39	antibody	antibody	NOUN
cusj-5637	60	40	(	(	PUNCT
cusj-5637	60	41	pt18ps19	pt18ps19	NOUN
cusj-5637	60	42	,	,	PUNCT
cusj-5637	60	43	rabbit	rabbit	NOUN
cusj-5637	60	44	antibody	antibody	NOUN
cusj-5637	60	45	;	;	PUNCT
cusj-5637	60	46	cell	cell	NOUN
cusj-5637	60	47	signaling	signal	VERB
cusj-5637	60	48	technology	technology	NOUN
cusj-5637	60	49	)	)	PUNCT
cusj-5637	60	50	.	.	PUNCT
cusj-5637	61	1	later	later	ADV
cusj-5637	61	2	,	,	PUNCT
cusj-5637	61	3	cells	cell	NOUN
cusj-5637	61	4	were	be	AUX
cusj-5637	61	5	incubated	incubate	VERB
cusj-5637	61	6	at	at	ADP
cusj-5637	61	7	room	room	NOUN
cusj-5637	61	8	temperature	temperature	NOUN
cusj-5637	61	9	with	with	ADP
cusj-5637	61	10	alexa-568	alexa-568	NOUN
cusj-5637	61	11	conjugated	conjugated	ADJ
cusj-5637	61	12	secondary	secondary	ADJ
cusj-5637	61	13	antibodies	antibody	NOUN
cusj-5637	61	14	(	(	PUNCT
cusj-5637	61	15	invitrogen	invitrogen	PROPN
cusj-5637	61	16	)	)	PUNCT
cusj-5637	61	17	.	.	PUNCT
cusj-5637	61	18	
 	
 	SPACE
cusj-5637	62	1	images	image	NOUN
cusj-5637	62	2	were	be	AUX
cusj-5637	62	3	acquired	acquire	VERB
cusj-5637	62	4	on	on	ADP
cusj-5637	62	5	a	a	DET
cusj-5637	62	6	nikon	nikon	PROPN
cusj-5637	62	7	widefield	widefield	NOUN
cusj-5637	62	8	-	-	PUNCT
cusj-5637	62	9	inverted	invert	VERB
cusj-5637	62	10	microscope	microscope	NOUN
cusj-5637	62	11	using	use	VERB
cusj-5637	62	12	a	a	DET
cusj-5637	62	13	20×	20×	NUM
cusj-5637	62	14	objective	objective	NOUN
cusj-5637	62	15	under	under	ADP
cusj-5637	62	16	identical	identical	ADJ
cusj-5637	62	17	excitation	excitation	NOUN
cusj-5637	62	18	conditions	condition	NOUN
cusj-5637	62	19	.	.	PUNCT
cusj-5637	63	1	images	image	NOUN
cusj-5637	63	2	were	be	AUX
cusj-5637	63	3	analyzed	analyze	VERB
cusj-5637	63	4	for	for	ADP
cusj-5637	63	5	the	the	DET
cusj-5637	63	6	integrated	integrate	VERB
cusj-5637	63	7	density	density	NOUN
cusj-5637	63	8	of	of	ADP
cusj-5637	63	9	the	the	DET
cusj-5637	63	10	signal	signal	NOUN
cusj-5637	63	11	using	use	VERB
cusj-5637	63	12	imagej	imagej	ADV
cusj-5637	63	13	(	(	PUNCT
cusj-5637	63	14	national	national	PROPN
cusj-5637	63	15	institute	institute	PROPN
cusj-5637	63	16	of	of	ADP
cusj-5637	63	17	health	health	NOUN
cusj-5637	63	18	)	)	PUNCT
cusj-5637	63	19	,	,	PUNCT
cusj-5637	63	20	and	and	CCONJ
cusj-5637	63	21	results	result	NOUN
cusj-5637	63	22	were	be	AUX
cusj-5637	63	23	imported	import	VERB
cusj-5637	63	24	into	into	ADP
cusj-5637	63	25	microsoft	microsoft	PROPN
cusj-5637	63	26	excel	excel	PROPN
cusj-5637	63	27	and	and	CCONJ
cusj-5637	63	28	values	value	NOUN
cusj-5637	63	29	were	be	AUX
cusj-5637	63	30	normalized	normalize	VERB
cusj-5637	63	31	to	to	ADP
cusj-5637	63	32	the	the	DET
cusj-5637	63	33	control	control	NOUN
cusj-5637	63	34	condition	condition	NOUN
cusj-5637	63	35	(	(	PUNCT
cusj-5637	63	36	bfp	bfp	NOUN
cusj-5637	63	37	only	only	ADV
cusj-5637	63	38	)	)	PUNCT
cusj-5637	63	39	,	,	PUNCT
cusj-5637	63	40	n=3	n=3	VERB
cusj-5637	63	41	.	.	PUNCT
cusj-5637	64	1	statistical	statistical	ADJ
cusj-5637	64	2	tests	test	NOUN
cusj-5637	64	3	significance	significance	NOUN
cusj-5637	64	4	was	be	AUX
cusj-5637	64	5	determined	determine	VERB
cusj-5637	64	6	by	by	ADP
cusj-5637	64	7	student	student	NOUN
cusj-5637	64	8	's	's	PART
cusj-5637	64	9	t	t	PROPN
cusj-5637	64	10	-	-	PUNCT
cusj-5637	64	11	test	test	NOUN
cusj-5637	64	12	(	(	PUNCT
cusj-5637	64	13	paired	pair	VERB
cusj-5637	64	14	,	,	PUNCT
cusj-5637	64	15	two	two	NUM
cusj-5637	64	16	-	-	PUNCT
cusj-5637	64	17	tailed	tailed	ADJ
cusj-5637	64	18	unless	unless	SCONJ
cusj-5637	64	19	otherwise	otherwise	ADV
cusj-5637	64	20	_	_	PUNCT
cusj-5637	65	1	_	_	PUNCT
cusj-5637	66	1	_	_	PUNCT
cusj-5637	67	1	_	_	PUNCT
cusj-5637	68	1	_	_	PUNCT
cusj-5637	69	1	_	_	PUNCT
cusj-5637	70	1	_	_	PUNCT
cusj-5637	71	1	_	_	PUNCT
cusj-5637	72	1	_	_	PUNCT
cusj-5637	73	1	_	_	PRON
cusj-5637	73	2	biology	biology	NOUN
cusj-5637	73	3	http://en.wikipedia.org/wiki/dihttp://en.wikipedia.org/wiki/dihttp://en.wikipedia.org/wiki/thiazole	http://en.wikipedia.org/wiki/dihttp://en.wikipedia.org/wiki/dihttp://en.wikipedia.org/wiki/thiazole	NOUN
cusj-5637	73	4	http://en.wikipedia.org/wiki/phenyl	http://en.wikipedia.org/wiki/phenyl	NOUN
cusj-5637	73	5	http://en.wikipedia.org/wiki/tetrazole	http://en.wikipedia.org/wiki/tetrazole	PROPN
cusj-5637	73	6	http://en.wikipedia.org/wiki/purple	http://en.wikipedia.org/wiki/purple	PROPN
cusj-5637	73	7	http://en.wikipedia.org/wiki/formazan	http://en.wikipedia.org/wiki/formazan	PROPN
cusj-5637	73	8	columbia	columbia	PROPN
cusj-5637	73	9	undergraduate	undergraduate	PROPN
cusj-5637	73	10	science	science	PROPN
cusj-5637	73	11	journal	journal	PROPN
cusj-5637	73	12	open	open	ADJ
cusj-5637	73	13	-	-	PUNCT
cusj-5637	73	14	access	access	NOUN
cusj-5637	73	15	publication	publication	NOUN
cusj-5637	73	16	|	|	NOUN
cusj-5637	73	17	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5637	73	18	spring	spring	NOUN
cusj-5637	73	19	2014	2014	NUM
cusj-5637	73	20	|	|	ADV
cusj-5637	73	21	volume	volume	NOUN
cusj-5637	73	22	8	8	NUM
cusj-5637	73	23	6	6	NUM
cusj-5637	73	24	indicated	indicate	VERB
cusj-5637	73	25	)	)	PUNCT
cusj-5637	73	26	and	and	CCONJ
cusj-5637	73	27	a	a	DET
cusj-5637	73	28	p<0.05	p<0.05	NOUN
cusj-5637	73	29	was	be	AUX
cusj-5637	73	30	considered	consider	VERB
cusj-5637	73	31	significant	significant	ADJ
cusj-5637	73	32	.	.	PUNCT
cusj-5637	74	1	results	result	NOUN
cusj-5637	74	2	in	in	ADP
cusj-5637	74	3	order	order	NOUN
cusj-5637	74	4	to	to	PART
cusj-5637	74	5	test	test	VERB
cusj-5637	74	6	the	the	DET
cusj-5637	74	7	motility	motility	NOUN
cusj-5637	74	8	of	of	ADP
cusj-5637	74	9	untreated	untreated	ADJ
cusj-5637	74	10	and	and	CCONJ
cusj-5637	74	11	treated	treat	VERB
cusj-5637	74	12	cells	cell	NOUN
cusj-5637	74	13	and	and	CCONJ
cusj-5637	74	14	confirm	confirm	VERB
cusj-5637	74	15	fasudil	fasudil	NOUN
cusj-5637	74	16	would	would	AUX
cusj-5637	74	17	inhibit	inhibit	VERB
cusj-5637	74	18	glioma	glioma	NOUN
cusj-5637	74	19	cell	cell	NOUN
cusj-5637	74	20	migration	migration	NOUN
cusj-5637	74	21	to	to	ADP
cusj-5637	74	22	a	a	DET
cusj-5637	74	23	significant	significant	ADJ
cusj-5637	74	24	degree	degree	NOUN
cusj-5637	74	25	,	,	PUNCT
cusj-5637	74	26	transwell	transwell	NOUN
cusj-5637	74	27	migration	migration	NOUN
cusj-5637	74	28	assays	assay	NOUN
cusj-5637	74	29	(	(	PUNCT
cusj-5637	74	30	tma	tma	PROPN
cusj-5637	74	31	)	)	PUNCT
cusj-5637	74	32	were	be	AUX
cusj-5637	74	33	the	the	DET
cusj-5637	74	34	assay	assay	NOUN
cusj-5637	74	35	of	of	ADP
cusj-5637	74	36	choice	choice	NOUN
cusj-5637	74	37	.	.	PUNCT
cusj-5637	75	1	transfilters	transfilter	NOUN
cusj-5637	75	2	provide	provide	VERB
cusj-5637	75	3	3	3	NUM
cusj-5637	75	4	μm	μm	NOUN
cusj-5637	75	5	pore	pore	ADJ
cusj-5637	75	6	sizes	size	NOUN
cusj-5637	75	7	comparable	comparable	ADJ
cusj-5637	75	8	to	to	ADP
cusj-5637	75	9	sizes	size	NOUN
cusj-5637	75	10	of	of	ADP
cusj-5637	75	11	pores	pore	NOUN
cusj-5637	75	12	that	that	PRON
cusj-5637	75	13	exist	exist	VERB
cusj-5637	75	14	in	in	ADP
cusj-5637	75	15	the	the	DET
cusj-5637	75	16	brain	brain	NOUN
cusj-5637	75	17	through	through	ADP
cusj-5637	75	18	which	which	PRON
cusj-5637	75	19	glioma	glioma	NOUN
cusj-5637	75	20	cells	cell	NOUN
cusj-5637	75	21	would	would	AUX
cusj-5637	75	22	need	need	VERB
cusj-5637	75	23	to	to	PART
cusj-5637	75	24	migrate	migrate	VERB
cusj-5637	75	25	[	[	X
cusj-5637	75	26	1	1	NUM
cusj-5637	75	27	]	]	PUNCT
cusj-5637	75	28	.	.	PUNCT
cusj-5637	76	1	figure	figure	NOUN
cusj-5637	76	2	1	1	NUM
cusj-5637	76	3	demonstrates	demonstrate	VERB
cusj-5637	76	4	the	the	DET
cusj-5637	76	5	relative	relative	ADJ
cusj-5637	76	6	size	size	NOUN
cusj-5637	76	7	of	of	ADP
cusj-5637	76	8	the	the	DET
cusj-5637	76	9	glioma	glioma	NOUN
cusj-5637	76	10	cells	cell	NOUN
cusj-5637	76	11	compared	compare	VERB
cusj-5637	76	12	to	to	ADP
cusj-5637	76	13	the	the	DET
cusj-5637	76	14	small	small	ADJ
cusj-5637	76	15	pore	pore	NOUN
cusj-5637	76	16	that	that	SCONJ
cusj-5637	76	17	it	it	PRON
cusj-5637	76	18	must	must	AUX
cusj-5637	76	19	migrate	migrate	VERB
cusj-5637	76	20	through	through	ADV
cusj-5637	76	21	.	.	PUNCT
cusj-5637	77	1	the	the	DET
cusj-5637	77	2	tmas	tma	NOUN
cusj-5637	77	3	evaluate	evaluate	VERB
cusj-5637	77	4	chemokinetic	chemokinetic	ADJ
cusj-5637	77	5	migration	migration	NOUN
cusj-5637	77	6	as	as	ADP
cusj-5637	77	7	either	either	DET
cusj-5637	77	8	side	side	NOUN
cusj-5637	77	9	of	of	ADP
cusj-5637	77	10	the	the	DET
cusj-5637	77	11	filter	filter	NOUN
cusj-5637	77	12	membrane	membrane	NOUN
cusj-5637	77	13	contains	contain	VERB
cusj-5637	77	14	media	medium	NOUN
cusj-5637	77	15	supplemented	supplement	VERB
cusj-5637	77	16	with	with	ADP
cusj-5637	77	17	growth	growth	NOUN
cusj-5637	77	18	factors	factor	NOUN
cusj-5637	77	19	that	that	PRON
cusj-5637	77	20	act	act	VERB
cusj-5637	77	21	as	as	ADP
cusj-5637	77	22	chemoattractants	chemoattractant	NOUN
cusj-5637	77	23	.	.	PUNCT
cusj-5637	78	1	this	this	DET
cusj-5637	78	2	approach	approach	NOUN
cusj-5637	78	3	mimics	mimic	VERB
cusj-5637	78	4	a	a	DET
cusj-5637	78	5	native	native	ADJ
cusj-5637	78	6	environment	environment	NOUN
cusj-5637	78	7	similar	similar	ADJ
cusj-5637	78	8	to	to	ADP
cusj-5637	78	9	that	that	PRON
cusj-5637	78	10	which	which	PRON
cusj-5637	78	11	exists	exist	VERB
cusj-5637	78	12	in	in	ADP
cusj-5637	78	13	the	the	DET
cusj-5637	78	14	brain	brain	NOUN
cusj-5637	78	15	.	.	PUNCT
cusj-5637	79	1	figure	figure	NOUN
cusj-5637	79	2	1	1	NUM
cusj-5637	79	3	:	:	PUNCT
cusj-5637	79	4	glioma	glioma	NOUN
cusj-5637	79	5	migration	migration	NOUN
cusj-5637	79	6	through	through	ADP
cusj-5637	79	7	3	3	NUM
cusj-5637	79	8	μm	μm	NOUN
cusj-5637	79	9	transwell	transwell	NOUN
cusj-5637	79	10	membranes	membrane	NOUN
cusj-5637	79	11	.	.	PUNCT
cusj-5637	80	1	representative	representative	ADJ
cusj-5637	80	2	image	image	NOUN
cusj-5637	80	3	of	of	ADP
cusj-5637	80	4	the	the	DET
cusj-5637	80	5	top	top	NOUN
cusj-5637	80	6	of	of	ADP
cusj-5637	80	7	a	a	DET
cusj-5637	80	8	transfilter	transfilter	ADJ
cusj-5637	80	9	membrane	membrane	NOUN
cusj-5637	80	10	stained	stain	VERB
cusj-5637	80	11	with	with	ADP
cusj-5637	80	12	ps19	ps19	PROPN
cusj-5637	80	13	-	-	PUNCT
cusj-5637	80	14	rlc	rlc	PROPN
cusj-5637	80	15	antibody	antibody	NOUN
cusj-5637	80	16	showing	show	VERB
cusj-5637	80	17	the	the	DET
cusj-5637	80	18	relative	relative	ADJ
cusj-5637	80	19	sizes	size	NOUN
cusj-5637	80	20	of	of	ADP
cusj-5637	80	21	the	the	DET
cusj-5637	80	22	control	control	NOUN
cusj-5637	80	23	glioma	glioma	NOUN
cusj-5637	80	24	cell	cell	NOUN
cusj-5637	80	25	and	and	CCONJ
cusj-5637	80	26	the	the	DET
cusj-5637	80	27	3	3	NUM
cusj-5637	80	28	μm	μm	NOUN
cusj-5637	80	29	pore	pore	NOUN
cusj-5637	80	30	.	.	PUNCT
cusj-5637	81	1	purple	purple	ADJ
cusj-5637	81	2	color	color	NOUN
cusj-5637	81	3	represents	represent	VERB
cusj-5637	81	4	cell	cell	NOUN
cusj-5637	81	5	nuclei	nucleus	NOUN
cusj-5637	81	6	;	;	PUNCT
cusj-5637	81	7	green	green	ADJ
cusj-5637	81	8	color	color	NOUN
cusj-5637	81	9	represents	represent	VERB
cusj-5637	81	10	phosphorylation	phosphorylation	NOUN
cusj-5637	81	11	at	at	ADP
cusj-5637	81	12	serine	serine	NOUN
cusj-5637	81	13	19	19	NUM
cusj-5637	81	14	site	site	NOUN
cusj-5637	81	15	;	;	PUNCT
cusj-5637	81	16	black	black	ADJ
cusj-5637	81	17	dots	dot	NOUN
cusj-5637	81	18	represent	represent	VERB
cusj-5637	81	19	3	3	NUM
cusj-5637	81	20	μm	μm	NOUN
cusj-5637	81	21	pores	pore	NOUN
cusj-5637	81	22	through	through	ADP
cusj-5637	81	23	which	which	PRON
cusj-5637	81	24	cells	cell	NOUN
cusj-5637	81	25	migrated	migrate	VERB
cusj-5637	81	26	.	.	PUNCT
cusj-5637	82	1	in	in	ADP
cusj-5637	82	2	order	order	NOUN
cusj-5637	82	3	to	to	PART
cusj-5637	82	4	identify	identify	VERB
cusj-5637	82	5	non	non	ADJ
cusj-5637	82	6	-	-	ADJ
cusj-5637	82	7	toxic	toxic	ADJ
cusj-5637	82	8	drug	drug	NOUN
cusj-5637	82	9	concentrations	concentration	NOUN
cusj-5637	82	10	for	for	ADP
cusj-5637	82	11	the	the	DET
cusj-5637	82	12	tma	tma	PROPN
cusj-5637	82	13	experiments	experiment	NOUN
cusj-5637	82	14	,	,	PUNCT
cusj-5637	82	15	we	we	PRON
cusj-5637	82	16	conducted	conduct	VERB
cusj-5637	82	17	a	a	DET
cusj-5637	82	18	dose	dose	NOUN
cusj-5637	82	19	response	response	NOUN
cusj-5637	82	20	assay	assay	VERB
cusj-5637	82	21	,	,	PUNCT
cusj-5637	82	22	specifically	specifically	ADV
cusj-5637	82	23	a	a	DET
cusj-5637	82	24	colorimetric	colorimetric	ADJ
cusj-5637	82	25	mtt	mtt	NOUN
cusj-5637	82	26	assay	assay	VERB
cusj-5637	82	27	.	.	PUNCT
cusj-5637	83	1	from	from	ADP
cusj-5637	83	2	this	this	DET
cusj-5637	83	3	assay	assay	NOUN
cusj-5637	83	4	,	,	PUNCT
cusj-5637	83	5	we	we	PRON
cusj-5637	83	6	determined	determine	VERB
cusj-5637	83	7	that	that	SCONJ
cusj-5637	83	8	100	100	NUM
cusj-5637	83	9	μm	μm	NUM
cusj-5637	83	10	fasudil	fasudil	NOUN
cusj-5637	83	11	is	be	AUX
cusj-5637	83	12	the	the	DET
cusj-5637	83	13	highest	high	ADJ
cusj-5637	83	14	concentration	concentration	NOUN
cusj-5637	83	15	that	that	PRON
cusj-5637	83	16	can	can	AUX
cusj-5637	83	17	be	be	AUX
cusj-5637	83	18	used	use	VERB
cusj-5637	83	19	without	without	ADP
cusj-5637	83	20	affecting	affect	VERB
cusj-5637	83	21	cell	cell	NOUN
cusj-5637	83	22	survival	survival	NOUN
cusj-5637	83	23	(	(	PUNCT
cusj-5637	83	24	figure	figure	NOUN
cusj-5637	83	25	2	2	NUM
cusj-5637	83	26	)	)	PUNCT
cusj-5637	83	27	.	.	PUNCT
cusj-5637	84	1	cells	cell	NOUN
cusj-5637	84	2	treated	treat	VERB
cusj-5637	84	3	with	with	ADP
cusj-5637	84	4	equivalent	equivalent	ADJ
cusj-5637	84	5	amounts	amount	NOUN
cusj-5637	84	6	of	of	ADP
cusj-5637	84	7	y-27632	y-27632	PROPN
cusj-5637	84	8	demonstrated	demonstrate	VERB
cusj-5637	84	9	more	more	ADJ
cusj-5637	84	10	cell	cell	NOUN
cusj-5637	84	11	viability	viability	NOUN
cusj-5637	84	12	although	although	SCONJ
cusj-5637	84	13	cells	cell	NOUN
cusj-5637	84	14	tolerate	tolerate	VERB
cusj-5637	84	15	both	both	DET
cusj-5637	84	16	inhibitors	inhibitor	NOUN
cusj-5637	84	17	at	at	ADP
cusj-5637	84	18	high	high	ADJ
cusj-5637	84	19	concentrations	concentration	NOUN
cusj-5637	84	20	(	(	PUNCT
cusj-5637	84	21	figure	figure	NOUN
cusj-5637	84	22	2	2	NUM
cusj-5637	84	23	)	)	PUNCT
cusj-5637	84	24	.	.	PUNCT
cusj-5637	85	1	500	500	NUM
cusj-5637	85	2	μm	μm	NOUN
cusj-5637	85	3	was	be	AUX
cusj-5637	85	4	chosen	choose	VERB
cusj-5637	85	5	as	as	ADP
cusj-5637	85	6	the	the	DET
cusj-5637	85	7	designated	designate	VERB
cusj-5637	85	8	y-27632	y-27632	PROPN
cusj-5637	85	9	concentration	concentration	NOUN
cusj-5637	85	10	because	because	SCONJ
cusj-5637	85	11	previous	previous	ADJ
cusj-5637	85	12	studies	study	NOUN
cusj-5637	85	13	used	use	VERB
cusj-5637	85	14	50	50	NUM
cusj-5637	85	15	μm	μm	NOUN
cusj-5637	85	16	y-27632	y-27632	PROPN
cusj-5637	85	17	as	as	ADP
cusj-5637	85	18	an	an	DET
cusj-5637	85	19	established	establish	VERB
cusj-5637	85	20	,	,	PUNCT
cusj-5637	85	21	effective	effective	ADJ
cusj-5637	85	22	concentration	concentration	NOUN
cusj-5637	85	23	for	for	ADP
cusj-5637	85	24	inhibition	inhibition	NOUN
cusj-5637	85	25	and	and	CCONJ
cusj-5637	85	26	a	a	DET
cusj-5637	85	27	tenfold	tenfold	ADJ
cusj-5637	85	28	increase	increase	NOUN
cusj-5637	85	29	would	would	AUX
cusj-5637	85	30	create	create	VERB
cusj-5637	85	31	an	an	DET
cusj-5637	85	32	extreme	extreme	ADJ
cusj-5637	85	33	concentration	concentration	NOUN
cusj-5637	85	34	point	point	NOUN
cusj-5637	85	35	that	that	PRON
cusj-5637	85	36	could	could	AUX
cusj-5637	85	37	help	help	VERB
cusj-5637	85	38	further	far	ADV
cusj-5637	85	39	elucidate	elucidate	VERB
cusj-5637	85	40	the	the	DET
cusj-5637	85	41	effect	effect	NOUN
cusj-5637	85	42	of	of	ADP
cusj-5637	85	43	fasudil	fasudil	NOUN
cusj-5637	86	1	[	[	X
cusj-5637	86	2	1	1	NUM
cusj-5637	86	3	]	]	PUNCT
cusj-5637	86	4	.	.	PUNCT
cusj-5637	87	1	figure	figure	NOUN
cusj-5637	87	2	2	2	NUM
cusj-5637	87	3	:	:	PUNCT
cusj-5637	87	4	mtt	mtt	NOUN
cusj-5637	87	5	assay	assay	VERB
cusj-5637	87	6	demonstrating	demonstrate	VERB
cusj-5637	87	7	cell	cell	NOUN
cusj-5637	87	8	viability	viability	NOUN
cusj-5637	87	9	for	for	ADP
cusj-5637	87	10	different	different	ADJ
cusj-5637	87	11	concentrations	concentration	NOUN
cusj-5637	87	12	of	of	ADP
cusj-5637	87	13	rock	rock	NOUN
cusj-5637	87	14	inhibitors	inhibitor	NOUN
cusj-5637	87	15	.	.	PUNCT
cusj-5637	88	1	dose	dose	VERB
cusj-5637	88	2	response	response	NOUN
cusj-5637	88	3	curves	curve	NOUN
cusj-5637	88	4	for	for	ADP
cusj-5637	88	5	mgpp3	mgpp3	ADJ
cusj-5637	88	6	cells	cell	NOUN
cusj-5637	88	7	treated	treat	VERB
cusj-5637	88	8	with	with	ADP
cusj-5637	88	9	either	either	CCONJ
cusj-5637	88	10	fasudil	fasudil	NOUN
cusj-5637	88	11	or	or	CCONJ
cusj-5637	88	12	y-27632	y-27632	PROPN
cusj-5637	88	13	for	for	ADP
cusj-5637	88	14	6	6	NUM
cusj-5637	88	15	hours	hour	NOUN
cusj-5637	88	16	.	.	PUNCT
cusj-5637	89	1	each	each	DET
cusj-5637	89	2	point	point	NOUN
cusj-5637	89	3	on	on	ADP
cusj-5637	89	4	the	the	DET
cusj-5637	89	5	curve	curve	NOUN
cusj-5637	89	6	represents	represent	VERB
cusj-5637	89	7	the	the	DET
cusj-5637	89	8	average	average	NOUN
cusj-5637	89	9	of	of	ADP
cusj-5637	89	10	five	five	NUM
cusj-5637	89	11	trials	trial	NOUN
cusj-5637	89	12	for	for	ADP
cusj-5637	89	13	each	each	DET
cusj-5637	89	14	condition	condition	NOUN
cusj-5637	89	15	and	and	CCONJ
cusj-5637	89	16	the	the	DET
cusj-5637	89	17	error	error	NOUN
cusj-5637	89	18	bars	bar	NOUN
cusj-5637	89	19	represent	represent	VERB
cusj-5637	89	20	standard	standard	ADJ
cusj-5637	89	21	error	error	NOUN
cusj-5637	89	22	.	.	PUNCT
cusj-5637	90	1	cell	cell	NOUN
cusj-5637	90	2	survival	survival	NOUN
cusj-5637	90	3	(	(	PUNCT
cusj-5637	90	4	y	y	NOUN
cusj-5637	90	5	-	-	PUNCT
cusj-5637	90	6	axis	axis	NOUN
cusj-5637	90	7	values	value	NOUN
cusj-5637	90	8	)	)	PUNCT
cusj-5637	90	9	was	be	AUX
cusj-5637	90	10	normalized	normalize	VERB
cusj-5637	90	11	to	to	ADP
cusj-5637	90	12	the	the	DET
cusj-5637	90	13	absorbance	absorbance	NOUN
cusj-5637	90	14	levels	level	NOUN
cusj-5637	90	15	measured	measure	VERB
cusj-5637	90	16	in	in	ADP
cusj-5637	90	17	cells	cell	NOUN
cusj-5637	90	18	treated	treat	VERB
cusj-5637	90	19	with	with	ADP
cusj-5637	90	20	only	only	ADJ
cusj-5637	90	21	h2o	h2o	PROPN
cusj-5637	90	22	,	,	PUNCT
cusj-5637	90	23	pvalues	pvalue	NOUN
cusj-5637	90	24	for	for	ADP
cusj-5637	90	25	concentrations	concentration	NOUN
cusj-5637	90	26	greater	great	ADJ
cusj-5637	90	27	than	than	ADP
cusj-5637	90	28	100	100	NUM
cusj-5637	90	29	μm	μm	NUM
cusj-5637	90	30	determined	determine	VERB
cusj-5637	90	31	by	by	ADP
cusj-5637	90	32	a	a	DET
cusj-5637	90	33	student	student	NOUN
cusj-5637	90	34	’s	’s	PART
cusj-5637	90	35	t	t	PROPN
cusj-5637	90	36	-	-	PUNCT
cusj-5637	90	37	test	test	NOUN
cusj-5637	90	38	(	(	PUNCT
cusj-5637	90	39	unpaired	unpaired	ADJ
cusj-5637	90	40	,	,	PUNCT
cusj-5637	90	41	onetailed	onetaile	VERB
cusj-5637	90	42	)	)	PUNCT
cusj-5637	90	43	are	be	AUX
cusj-5637	90	44	labeled	label	VERB
cusj-5637	90	45	in	in	ADP
cusj-5637	90	46	the	the	DET
cusj-5637	90	47	corresponding	correspond	VERB
cusj-5637	90	48	color	color	NOUN
cusj-5637	90	49	above	above	ADP
cusj-5637	90	50	the	the	DET
cusj-5637	90	51	points	point	NOUN
cusj-5637	90	52	.	.	PUNCT
cusj-5637	91	1	as	as	ADP
cusj-5637	91	2	figure	figure	NOUN
cusj-5637	91	3	3	3	NUM
cusj-5637	91	4	shows	show	NOUN
cusj-5637	91	5	,	,	PUNCT
cusj-5637	91	6	100	100	NUM
cusj-5637	91	7	μm	μm	NUM
cusj-5637	91	8	fasudil	fasudil	NOUN
cusj-5637	91	9	reduces	reduce	VERB
cusj-5637	91	10	trans	trans	ADJ
cusj-5637	91	11	-	-	ADJ
cusj-5637	91	12	membrane	membrane	ADJ
cusj-5637	91	13	migration	migration	NOUN
cusj-5637	91	14	of	of	ADP
cusj-5637	91	15	cells	cell	NOUN
cusj-5637	91	16	to	to	ADP
cusj-5637	91	17	25.36	25.36	NUM
cusj-5637	91	18	%	%	NOUN
cusj-5637	91	19	compared	compare	VERB
cusj-5637	91	20	to	to	ADP
cusj-5637	91	21	the	the	DET
cusj-5637	91	22	control	control	NOUN
cusj-5637	91	23	condition	condition	NOUN
cusj-5637	91	24	(	(	PUNCT
cusj-5637	91	25	p=0.009	p=0.009	NOUN
cusj-5637	91	26	)	)	PUNCT
cusj-5637	91	27	.	.	PUNCT
cusj-5637	92	1	500	500	NUM
cusj-5637	92	2	μm	μm	NOUN
cusj-5637	92	3	y-27632	y-27632	PROPN
cusj-5637	92	4	also	also	ADV
cusj-5637	92	5	significantly	significantly	ADV
cusj-5637	92	6	reduces	reduce	VERB
cusj-5637	92	7	cell	cell	NOUN
cusj-5637	92	8	migration	migration	NOUN
cusj-5637	92	9	to	to	ADP
cusj-5637	92	10	17.14	17.14	NUM
cusj-5637	92	11	%	%	NOUN
cusj-5637	92	12	(	(	PUNCT
cusj-5637	92	13	p=0.0055	p=0.0055	NOUN
cusj-5637	92	14	)	)	PUNCT
cusj-5637	92	15	.	.	PUNCT
cusj-5637	93	1	on	on	ADP
cusj-5637	93	2	the	the	DET
cusj-5637	93	3	other	other	ADJ
cusj-5637	93	4	hand	hand	NOUN
cusj-5637	93	5	,	,	PUNCT
cusj-5637	93	6	the	the	DET
cusj-5637	93	7	difference	difference	NOUN
cusj-5637	93	8	in	in	ADP
cusj-5637	93	9	motility	motility	NOUN
cusj-5637	93	10	between	between	ADP
cusj-5637	93	11	fasudil	fasudil	NOUN
cusj-5637	93	12	-	-	PUNCT
cusj-5637	93	13	treated	treat	VERB
cusj-5637	93	14	cells	cell	NOUN
cusj-5637	93	15	compared	compare	VERB
cusj-5637	93	16	to	to	ADP
cusj-5637	93	17	y-27632	y-27632	ADV
cusj-5637	93	18	-	-	PUNCT
cusj-5637	93	19	treated	treat	VERB
cusj-5637	93	20	cells	cell	NOUN
cusj-5637	93	21	is	be	AUX
cusj-5637	93	22	just	just	ADV
cusj-5637	93	23	under	under	ADP
cusj-5637	93	24	p=0.05	p=0.05	NOUN
cusj-5637	93	25	(	(	PUNCT
cusj-5637	93	26	p=0.04985	p=0.04985	X
cusj-5637	93	27	)	)	PUNCT
cusj-5637	93	28	,	,	PUNCT
cusj-5637	93	29	despite	despite	SCONJ
cusj-5637	93	30	the	the	DET
cusj-5637	93	31	much	much	ADV
cusj-5637	93	32	higher	high	ADJ
cusj-5637	93	33	dosage	dosage	NOUN
cusj-5637	93	34	of	of	ADP
cusj-5637	93	35	y-27632	y-27632	PROPN
cusj-5637	93	36	.	.	PUNCT
cusj-5637	93	37	biology	biology	PROPN
cusj-5637	93	38	columbia	columbia	PROPN
cusj-5637	93	39	undergraduate	undergraduate	PROPN
cusj-5637	93	40	science	science	PROPN
cusj-5637	93	41	journal	journal	PROPN
cusj-5637	93	42	open	open	ADJ
cusj-5637	93	43	-	-	PUNCT
cusj-5637	93	44	access	access	NOUN
cusj-5637	93	45	publication	publication	NOUN
cusj-5637	93	46	|	|	NOUN
cusj-5637	93	47	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5637	93	48	spring	spring	NOUN
cusj-5637	93	49	2014	2014	NUM
cusj-5637	93	50	|	|	ADV
cusj-5637	93	51	volume	volume	NOUN
cusj-5637	93	52	8	8	NUM
cusj-5637	93	53	7	7	NUM
cusj-5637	93	54	a.	a.	NOUN
cusj-5637	93	55	effect	effect	NOUN
cusj-5637	93	56	of	of	ADP
cusj-5637	93	57	rock	rock	NOUN
cusj-5637	93	58	inhibitors	inhibitor	NOUN
cusj-5637	93	59	on	on	ADP
cusj-5637	93	60	cell	cell	NOUN
cusj-5637	93	61	migration	migration	NOUN
cusj-5637	93	62	through	through	ADP
cusj-5637	93	63	3	3	NUM
cusj-5637	93	64	μm	μm	NUM
cusj-5637	93	65	transwell	transwell	NOUN
cusj-5637	93	66	membranes	membrane	NOUN
cusj-5637	93	67	.	.	PUNCT
cusj-5637	94	1	c	c	X
cusj-5637	94	2	)	)	PUNCT
cusj-5637	94	3	fasudil	fasudil	NOUN
cusj-5637	94	4	-	-	PUNCT
cusj-5637	94	5	treated	treat	VERB
cusj-5637	94	6	d	d	NOUN
cusj-5637	94	7	)	)	PUNCT
cusj-5637	94	8	y27632	y27632	PROPN
cusj-5637	94	9	b	b	X
cusj-5637	94	10	)	)	PUNCT
cusj-5637	94	11	control	control	NOUN
cusj-5637	94	12	cells	cell	NOUN
cusj-5637	94	13	cells	cell	NOUN
cusj-5637	94	14	treated	treat	VERB
cusj-5637	94	15	cells	cell	NOUN
cusj-5637	94	16	figure	figure	VERB
cusj-5637	94	17	3	3	NUM
cusj-5637	94	18	:	:	PUNCT
cusj-5637	94	19	cell	cell	NOUN
cusj-5637	94	20	migration	migration	NOUN
cusj-5637	94	21	in	in	ADP
cusj-5637	94	22	transwell	transwell	NOUN
cusj-5637	94	23	migration	migration	NOUN
cusj-5637	94	24	assays	assay	NOUN
cusj-5637	94	25	.	.	PUNCT
cusj-5637	95	1	(	(	PUNCT
cusj-5637	95	2	a.	a.	NOUN
cusj-5637	95	3	)	)	PUNCT
cusj-5637	95	4	percent	percent	NOUN
cusj-5637	95	5	migration	migration	NOUN
cusj-5637	95	6	was	be	AUX
cusj-5637	95	7	normalized	normalize	VERB
cusj-5637	95	8	to	to	ADP
cusj-5637	95	9	the	the	DET
cusj-5637	95	10	number	number	NOUN
cusj-5637	95	11	of	of	ADP
cusj-5637	95	12	migrated	migrate	VERB
cusj-5637	95	13	control	control	NOUN
cusj-5637	95	14	cells	cell	NOUN
cusj-5637	95	15	,	,	PUNCT
cusj-5637	95	16	error	error	NOUN
cusj-5637	95	17	bars	bar	NOUN
cusj-5637	95	18	represent	represent	VERB
cusj-5637	95	19	standard	standard	ADJ
cusj-5637	95	20	error	error	NOUN
cusj-5637	95	21	of	of	ADP
cusj-5637	95	22	the	the	DET
cusj-5637	95	23	averages	average	NOUN
cusj-5637	95	24	of	of	ADP
cusj-5637	95	25	the	the	DET
cusj-5637	95	26	nuclei	nucleus	NOUN
cusj-5637	95	27	count	count	VERB
cusj-5637	95	28	from	from	ADP
cusj-5637	95	29	five	five	NUM
cusj-5637	95	30	representative	representative	ADJ
cusj-5637	95	31	fields	field	NOUN
cusj-5637	95	32	of	of	ADP
cusj-5637	95	33	each	each	DET
cusj-5637	95	34	filter	filter	NOUN
cusj-5637	95	35	at	at	ADP
cusj-5637	95	36	4x	4x	NUM
cusj-5637	95	37	magnification	magnification	NOUN
cusj-5637	95	38	and	and	CCONJ
cusj-5637	95	39	p	p	NOUN
cusj-5637	95	40	-	-	PUNCT
cusj-5637	95	41	values	value	NOUN
cusj-5637	95	42	are	be	AUX
cusj-5637	95	43	listed	list	VERB
cusj-5637	95	44	above	above	ADP
cusj-5637	95	45	the	the	DET
cusj-5637	95	46	bars	bar	NOUN
cusj-5637	95	47	.	.	PUNCT
cusj-5637	96	1	representative	representative	ADJ
cusj-5637	96	2	images	image	NOUN
cusj-5637	96	3	of	of	ADP
cusj-5637	96	4	the	the	DET
cusj-5637	96	5	bottom	bottom	ADJ
cusj-5637	96	6	portion	portion	NOUN
cusj-5637	96	7	of	of	ADP
cusj-5637	96	8	transfilters	transfilter	NOUN
cusj-5637	96	9	used	use	VERB
cusj-5637	96	10	in	in	ADP
cusj-5637	96	11	tma	tma	PROPN
cusj-5637	96	12	experiments	experiment	NOUN
cusj-5637	96	13	after	after	SCONJ
cusj-5637	96	14	mgpp3	mgpp3	ADJ
cusj-5637	96	15	cells	cell	NOUN
cusj-5637	96	16	were	be	AUX
cusj-5637	96	17	incubated	incubate	VERB
cusj-5637	96	18	for	for	ADP
cusj-5637	96	19	6	6	NUM
cusj-5637	96	20	hours	hour	NOUN
cusj-5637	96	21	at	at	ADP
cusj-5637	96	22	37	37	NUM
cusj-5637	96	23	°	°	ADP
cusj-5637	96	24	c	c	NOUN
cusj-5637	96	25	with	with	ADP
cusj-5637	96	26	either	either	CCONJ
cusj-5637	96	27	10	10	NUM
cusj-5637	96	28	%	%	NOUN
cusj-5637	96	29	fbs	fbs	NOUN
cusj-5637	96	30	and	and	CCONJ
cusj-5637	96	31	were	be	AUX
cusj-5637	96	32	(	(	PUNCT
cusj-5637	96	33	b.	b.	NOUN
cusj-5637	96	34	)	)	PUNCT
cusj-5637	96	35	uninhibited	uninhibited	ADJ
cusj-5637	96	36	(	(	PUNCT
cusj-5637	96	37	control	control	NOUN
cusj-5637	96	38	)	)	PUNCT
cusj-5637	96	39	cells	cell	NOUN
cusj-5637	96	40	,	,	PUNCT
cusj-5637	96	41	(	(	PUNCT
cusj-5637	96	42	c.	c.	NOUN
cusj-5637	96	43	)	)	PUNCT
cusj-5637	96	44	fbs+100	fbs+100	NOUN
cusj-5637	96	45	μm	μm	NUM
cusj-5637	96	46	fasudil	fasudil	NOUN
cusj-5637	96	47	-	-	PUNCT
cusj-5637	96	48	treated	treat	VERB
cusj-5637	96	49	cells	cell	NOUN
cusj-5637	96	50	,	,	PUNCT
cusj-5637	96	51	or	or	CCONJ
cusj-5637	96	52	(	(	PUNCT
cusj-5637	96	53	d.	d.	NOUN
cusj-5637	96	54	)	)	PUNCT
cusj-5637	96	55	fbs+500	fbs+500	PROPN
cusj-5637	96	56	μm	μm	ADJ
cusj-5637	96	57	y-27632	y-27632	ADV
cusj-5637	96	58	-	-	PUNCT
cusj-5637	96	59	treated	treat	VERB
cusj-5637	96	60	cells	cell	NOUN
cusj-5637	96	61	.	.	PUNCT
cusj-5637	97	1	cells	cell	NOUN
cusj-5637	97	2	were	be	AUX
cusj-5637	97	3	fixed	fix	VERB
cusj-5637	97	4	and	and	CCONJ
cusj-5637	97	5	stained	stain	VERB
cusj-5637	97	6	with	with	ADP
cusj-5637	97	7	dapi	dapi	PROPN
cusj-5637	97	8	.	.	PUNCT
cusj-5637	98	1	each	each	DET
cusj-5637	98	2	experimental	experimental	ADJ
cusj-5637	98	3	condition	condition	NOUN
cusj-5637	98	4	was	be	AUX
cusj-5637	98	5	assessed	assess	VERB
cusj-5637	98	6	in	in	ADP
cusj-5637	98	7	triplicate	triplicate	NOUN
cusj-5637	98	8	for	for	ADP
cusj-5637	98	9	a	a	DET
cusj-5637	98	10	total	total	ADJ
cusj-5637	98	11	n=3	n=3	NOUN
cusj-5637	98	12	.	.	NOUN
cusj-5637	98	13	aside	aside	ADV
cusj-5637	98	14	from	from	ADP
cusj-5637	98	15	observing	observe	VERB
cusj-5637	98	16	the	the	DET
cusj-5637	98	17	difference	difference	NOUN
cusj-5637	98	18	rock	rock	NOUN
cusj-5637	98	19	inhibitors	inhibitor	NOUN
cusj-5637	98	20	can	can	AUX
cusj-5637	98	21	make	make	VERB
cusj-5637	98	22	on	on	ADP
cusj-5637	98	23	migration	migration	NOUN
cusj-5637	98	24	,	,	PUNCT
cusj-5637	98	25	it	it	PRON
cusj-5637	98	26	is	be	AUX
cusj-5637	98	27	also	also	ADV
cusj-5637	98	28	important	important	ADJ
cusj-5637	98	29	to	to	PART
cusj-5637	98	30	ascertain	ascertain	VERB
cusj-5637	98	31	whether	whether	SCONJ
cusj-5637	98	32	the	the	DET
cusj-5637	98	33	predicted	predict	VERB
cusj-5637	98	34	pathway	pathway	NOUN
cusj-5637	98	35	is	be	AUX
cusj-5637	98	36	operating	operate	VERB
cusj-5637	98	37	as	as	ADP
cusj-5637	98	38	expected	expect	VERB
cusj-5637	98	39	when	when	SCONJ
cusj-5637	98	40	inhibition	inhibition	NOUN
cusj-5637	98	41	occurs	occur	VERB
cusj-5637	98	42	.	.	PUNCT
cusj-5637	99	1	since	since	SCONJ
cusj-5637	99	2	phosphorylated	phosphorylate	VERB
cusj-5637	99	3	rlcs	rlcs	NOUN
cusj-5637	99	4	(	(	PUNCT
cusj-5637	99	5	phosphorlcs	phosphorlcs	ADV
cusj-5637	99	6	)	)	PUNCT
cusj-5637	99	7	are	be	AUX
cusj-5637	99	8	expected	expect	VERB
cusj-5637	99	9	to	to	PART
cusj-5637	99	10	be	be	AUX
cusj-5637	99	11	responsible	responsible	ADJ
cusj-5637	99	12	for	for	ADP
cusj-5637	99	13	much	much	ADJ
cusj-5637	99	14	of	of	ADP
cusj-5637	99	15	the	the	DET
cusj-5637	99	16	nmii	nmii	NOUN
cusj-5637	99	17	-	-	PUNCT
cusj-5637	99	18	dependent	dependent	ADJ
cusj-5637	99	19	contractions	contraction	NOUN
cusj-5637	99	20	within	within	ADP
cusj-5637	99	21	glioma	glioma	NOUN
cusj-5637	99	22	cells	cell	NOUN
cusj-5637	99	23	,	,	PUNCT
cusj-5637	99	24	fasudil	fasudil	NOUN
cusj-5637	99	25	and	and	CCONJ
cusj-5637	99	26	y-2632	y-2632	NOUN
cusj-5637	99	27	inhibition	inhibition	NOUN
cusj-5637	99	28	of	of	ADP
cusj-5637	99	29	rock	rock	NOUN
cusj-5637	99	30	should	should	AUX
cusj-5637	99	31	decrease	decrease	VERB
cusj-5637	99	32	motility	motility	NOUN
cusj-5637	99	33	after	after	ADP
cusj-5637	99	34	decreasing	decrease	VERB
cusj-5637	99	35	rlc	rlc	PROPN
cusj-5637	99	36	phosphorylation	phosphorylation	NOUN
cusj-5637	99	37	.	.	PUNCT
cusj-5637	100	1	in	in	ADP
cusj-5637	100	2	order	order	NOUN
cusj-5637	100	3	to	to	PART
cusj-5637	100	4	quantify	quantify	VERB
cusj-5637	100	5	this	this	DET
cusj-5637	100	6	observation	observation	NOUN
cusj-5637	100	7	and	and	CCONJ
cusj-5637	100	8	corroborate	corroborate	VERB
cusj-5637	100	9	this	this	PRON
cusj-5637	100	10	with	with	ADP
cusj-5637	100	11	previous	previous	ADJ
cusj-5637	100	12	findings	finding	NOUN
cusj-5637	100	13	,	,	PUNCT
cusj-5637	100	14	ptyb	ptyb	NOUN
cusj-5637	100	15	cells	cell	NOUN
cusj-5637	100	16	were	be	AUX
cusj-5637	100	17	stained	stain	VERB
cusj-5637	100	18	with	with	ADP
cusj-5637	100	19	the	the	DET
cusj-5637	100	20	same	same	ADJ
cusj-5637	100	21	ps19	ps19	PROPN
cusj-5637	100	22	and	and	CCONJ
cusj-5637	100	23	pt18ps19	pt18ps19	PROPN
cusj-5637	100	24	antibodies	antibodie	VERB
cusj-5637	100	25	after	after	ADP
cusj-5637	100	26	treatment	treatment	NOUN
cusj-5637	100	27	with	with	ADP
cusj-5637	100	28	60	60	NUM
cusj-5637	100	29	μm	μm	NUM
cusj-5637	100	30	fasudil	fasudil	NOUN
cusj-5637	100	31	(	(	PUNCT
cusj-5637	100	32	figure	figure	NOUN
cusj-5637	100	33	4a	4a	NUM
cusj-5637	100	34	,	,	PUNCT
cusj-5637	100	35	b	b	NOUN
cusj-5637	100	36	)	)	PUNCT
cusj-5637	100	37	or	or	CCONJ
cusj-5637	100	38	50	50	NUM
cusj-5637	100	39	μm	μm	NOUN
cusj-5637	101	1	y-27632	y-27632	PROPN
cusj-5637	101	2	(	(	PUNCT
cusj-5637	101	3	data	datum	NOUN
cusj-5637	101	4	not	not	PART
cusj-5637	101	5	shown	show	VERB
cusj-5637	101	6	)	)	PUNCT
cusj-5637	101	7	which	which	PRON
cusj-5637	101	8	were	be	AUX
cusj-5637	101	9	concentrations	concentration	NOUN
cusj-5637	101	10	used	use	VERB
cusj-5637	101	11	in	in	ADP
cusj-5637	101	12	other	other	ADJ
cusj-5637	101	13	studies	study	NOUN
cusj-5637	101	14	[	[	X
cusj-5637	101	15	1	1	NUM
cusj-5637	101	16	]	]	PUNCT
cusj-5637	101	17	.	.	PUNCT
cusj-5637	102	1	representative	representative	ADJ
cusj-5637	102	2	images	image	NOUN
cusj-5637	102	3	were	be	AUX
cusj-5637	102	4	captured	capture	VERB
cusj-5637	102	5	using	use	VERB
cusj-5637	102	6	a	a	DET
cusj-5637	102	7	wide	wide	ADJ
cusj-5637	102	8	-	-	PUNCT
cusj-5637	102	9	field	field	NOUN
cusj-5637	102	10	microscope	microscope	NOUN
cusj-5637	102	11	and	and	CCONJ
cusj-5637	102	12	integrated	integrate	VERB
cusj-5637	102	13	density	density	NOUN
cusj-5637	102	14	of	of	ADP
cusj-5637	102	15	the	the	DET
cusj-5637	102	16	signal	signal	NOUN
cusj-5637	102	17	was	be	AUX
cusj-5637	102	18	calculated	calculate	VERB
cusj-5637	102	19	(	(	PUNCT
cusj-5637	102	20	figure	figure	NOUN
cusj-5637	102	21	4a	4a	NUM
cusj-5637	102	22	,	,	PUNCT
cusj-5637	102	23	b	b	NOUN
cusj-5637	102	24	)	)	PUNCT
cusj-5637	102	25	.	.	PUNCT
cusj-5637	103	1	the	the	DET
cusj-5637	103	2	results	result	NOUN
cusj-5637	103	3	show	show	VERB
cusj-5637	103	4	a	a	DET
cusj-5637	103	5	47.99	47.99	NUM
cusj-5637	103	6	%	%	NOUN
cusj-5637	103	7	decrease	decrease	NOUN
cusj-5637	103	8	in	in	ADP
cusj-5637	103	9	phosphorylation	phosphorylation	NOUN
cusj-5637	103	10	of	of	ADP
cusj-5637	103	11	the	the	DET
cusj-5637	103	12	serine	serine	NOUN
cusj-5637	103	13	19	19	NUM
cusj-5637	103	14	site	site	NOUN
cusj-5637	103	15	when	when	SCONJ
cusj-5637	103	16	cells	cell	NOUN
cusj-5637	103	17	were	be	AUX
cusj-5637	103	18	treated	treat	VERB
cusj-5637	103	19	with	with	ADP
cusj-5637	103	20	60	60	NUM
cusj-5637	103	21	μm	μm	NUM
cusj-5637	103	22	fasudil	fasudil	NOUN
cusj-5637	103	23	compared	compare	VERB
cusj-5637	103	24	to	to	ADP
cusj-5637	103	25	control	control	NOUN
cusj-5637	103	26	(	(	PUNCT
cusj-5637	103	27	figure	figure	NOUN
cusj-5637	103	28	4d;;	4d;;	NUM
cusj-5637	103	29	p=0.006	p=0.006	NOUN
cusj-5637	103	30	)	)	PUNCT
cusj-5637	103	31	.	.	PUNCT
cusj-5637	104	1	similarly	similarly	ADV
cusj-5637	104	2	,	,	PUNCT
cusj-5637	104	3	50	50	NUM
cusj-5637	104	4	μm	μm	NOUN
cusj-5637	104	5	y27632	y27632	PROPN
cusj-5637	104	6	demonstrated	demonstrate	VERB
cusj-5637	104	7	a	a	DET
cusj-5637	104	8	41.93	41.93	NUM
cusj-5637	104	9	%	%	NOUN
cusj-5637	104	10	decrease	decrease	NOUN
cusj-5637	104	11	in	in	ADP
cusj-5637	104	12	monophosphorylation	monophosphorylation	NOUN
cusj-5637	104	13	(	(	PUNCT
cusj-5637	104	14	figure	figure	NOUN
cusj-5637	104	15	4d	4d	NUM
cusj-5637	104	16	;	;	PUNCT
cusj-5637	104	17	p=0.0046	p=0.0046	PROPN
cusj-5637	104	18	)	)	PUNCT
cusj-5637	104	19	.	.	PUNCT
cusj-5637	105	1	c.	c.	PROPN
cusj-5637	105	2	phosphorylation	phosphorylation	NOUN
cusj-5637	105	3	of	of	ADP
cusj-5637	105	4	cells	cell	NOUN
cusj-5637	105	5	w/	w/	X
cusj-5637	105	6	pt18ps19	pt18ps19	PROPN
cusj-5637	105	7	-	-	PUNCT
cusj-5637	105	8	rlc	rlc	PROPN
cusj-5637	105	9	biology	biology	PROPN
cusj-5637	105	10	columbia	columbia	PROPN
cusj-5637	105	11	undergraduate	undergraduate	PROPN
cusj-5637	105	12	science	science	PROPN
cusj-5637	105	13	journal	journal	PROPN
cusj-5637	105	14	open	open	ADJ
cusj-5637	105	15	-	-	PUNCT
cusj-5637	105	16	access	access	NOUN
cusj-5637	105	17	publication	publication	NOUN
cusj-5637	105	18	|	|	NOUN
cusj-5637	105	19	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5637	105	20	spring	spring	NOUN
cusj-5637	105	21	2014	2014	NUM
cusj-5637	106	1	|	|	ADV
cusj-5637	106	2	volume	volume	NOUN
cusj-5637	106	3	8	8	NUM
cusj-5637	106	4	8	8	NUM
cusj-5637	106	5	d.	d.	PROPN
cusj-5637	106	6	phosphorylation	phosphorylation	NOUN
cusj-5637	106	7	of	of	ADP
cusj-5637	106	8	cells	cell	NOUN
cusj-5637	106	9	w/	w/	NOUN
cusj-5637	106	10	ps19	ps19	PROPN
cusj-5637	106	11	-	-	PUNCT
cusj-5637	106	12	rlc	rlc	PROPN
cusj-5637	106	13	figure	figure	NOUN
cusj-5637	106	14	4	4	NUM
cusj-5637	106	15	:	:	PUNCT
cusj-5637	106	16	phospho	phospho	ADJ
cusj-5637	106	17	-	-	PUNCT
cusj-5637	106	18	rlc	rlc	PROPN
cusj-5637	106	19	staining	staining	NOUN
cusj-5637	106	20	.	.	PUNCT
cusj-5637	107	1	representative	representative	ADJ
cusj-5637	107	2	images	image	NOUN
cusj-5637	107	3	of	of	ADP
cusj-5637	107	4	ptyb	ptyb	NOUN
cusj-5637	107	5	cells	cell	NOUN
cusj-5637	107	6	treated	treat	VERB
cusj-5637	107	7	with	with	ADP
cusj-5637	107	8	bfp	bfp	NOUN
cusj-5637	107	9	media	medium	NOUN
cusj-5637	107	10	,	,	PUNCT
cusj-5637	107	11	or	or	CCONJ
cusj-5637	107	12	bfp+60μm	bfp+60μm	NUM
cusj-5637	107	13	fasudil	fasudil	NOUN
cusj-5637	107	14	for	for	ADP
cusj-5637	107	15	3	3	NUM
cusj-5637	107	16	hours	hour	NOUN
cusj-5637	107	17	before	before	ADP
cusj-5637	107	18	fixing	fix	VERB
cusj-5637	107	19	and	and	CCONJ
cusj-5637	107	20	staining	stain	VERB
cusj-5637	107	21	with	with	ADP
cusj-5637	107	22	dapi	dapi	PROPN
cusj-5637	107	23	and	and	CCONJ
cusj-5637	107	24	the	the	DET
cusj-5637	107	25	primary	primary	ADJ
cusj-5637	107	26	antibodies	antibody	NOUN
cusj-5637	107	27	(	(	PUNCT
cusj-5637	107	28	a.	a.	NOUN
cusj-5637	107	29	)	)	PUNCT
cusj-5637	107	30	pt18ps19	pt18ps19	PROPN
cusj-5637	107	31	-	-	PUNCT
cusj-5637	107	32	rlc	rlc	PROPN
cusj-5637	107	33	or	or	CCONJ
cusj-5637	107	34	(	(	PUNCT
cusj-5637	107	35	b.	b.	PROPN
cusj-5637	107	36	)	)	PUNCT
cusj-5637	108	1	ps19	ps19	PROPN
cusj-5637	108	2	-	-	PUNCT
cusj-5637	108	3	rlc	rlc	PROPN
cusj-5637	108	4	.	.	PUNCT
cusj-5637	109	1	underlying	underlie	VERB
cusj-5637	109	2	blue	blue	ADJ
cusj-5637	109	3	color	color	NOUN
cusj-5637	109	4	represents	represent	VERB
cusj-5637	109	5	dapi	dapi	ADJ
cusj-5637	109	6	staining	staining	NOUN
cusj-5637	109	7	of	of	ADP
cusj-5637	109	8	nuclei	nucleus	NOUN
cusj-5637	109	9	;	;	PUNCT
cusj-5637	109	10	red	red	ADJ
cusj-5637	109	11	color	color	NOUN
cusj-5637	109	12	represents	represent	VERB
cusj-5637	109	13	phospho	phospho	ADJ
cusj-5637	109	14	-	-	PUNCT
cusj-5637	109	15	rlc	rlc	NOUN
cusj-5637	109	16	.	.	PUNCT
cusj-5637	110	1	integrated	integrate	VERB
cusj-5637	110	2	density	density	NOUN
cusj-5637	110	3	of	of	ADP
cusj-5637	110	4	the	the	DET
cusj-5637	110	5	(	(	PUNCT
cusj-5637	110	6	c.	c.	NOUN
cusj-5637	110	7	)	)	PUNCT
cusj-5637	110	8	diphosphorylated	diphosphorylate	VERB
cusj-5637	110	9	-	-	PUNCT
cusj-5637	110	10	rlc	rlc	PROPN
cusj-5637	110	11	signal	signal	NOUN
cusj-5637	110	12	or	or	CCONJ
cusj-5637	110	13	(	(	PUNCT
cusj-5637	110	14	d.	d.	PROPN
cusj-5637	110	15	)	)	PUNCT
cusj-5637	110	16	monophosphorylated	monophosphorylate	VERB
cusj-5637	110	17	-	-	PUNCT
cusj-5637	110	18	rlc	rlc	PROPN
cusj-5637	110	19	signal	signal	NOUN
cusj-5637	110	20	was	be	AUX
cusj-5637	110	21	measured	measure	VERB
cusj-5637	110	22	from	from	ADP
cusj-5637	110	23	20	20	NUM
cusj-5637	110	24	cells	cell	NOUN
cusj-5637	110	25	per	per	ADP
cusj-5637	110	26	condition	condition	NOUN
cusj-5637	110	27	,	,	PUNCT
cusj-5637	110	28	averaged	average	VERB
cusj-5637	110	29	and	and	CCONJ
cusj-5637	110	30	normalized	normalize	VERB
cusj-5637	110	31	to	to	PART
cusj-5637	110	32	control	control	VERB
cusj-5637	110	33	ptyb	ptyb	NOUN
cusj-5637	110	34	cell	cell	NOUN
cusj-5637	110	35	phosphorylation	phosphorylation	NOUN
cusj-5637	110	36	.	.	PUNCT
cusj-5637	111	1	error	error	NOUN
cusj-5637	111	2	bars	bar	NOUN
cusj-5637	111	3	represent	represent	VERB
cusj-5637	111	4	standard	standard	ADJ
cusj-5637	111	5	error	error	NOUN
cusj-5637	111	6	of	of	ADP
cusj-5637	111	7	measurements	measurement	NOUN
cusj-5637	111	8	for	for	ADP
cusj-5637	111	9	each	each	DET
cusj-5637	111	10	condition	condition	NOUN
cusj-5637	111	11	and	and	CCONJ
cusj-5637	111	12	p	p	NOUN
cusj-5637	111	13	-	-	PUNCT
cusj-5637	111	14	values	value	NOUN
cusj-5637	111	15	are	be	AUX
cusj-5637	111	16	listed	list	VERB
cusj-5637	111	17	above	above	ADP
cusj-5637	111	18	the	the	DET
cusj-5637	111	19	corresponding	corresponding	ADJ
cusj-5637	111	20	bars	bar	NOUN
cusj-5637	111	21	.	.	PUNCT
cusj-5637	112	1	after	after	ADP
cusj-5637	112	2	measuring	measure	VERB
cusj-5637	112	3	the	the	DET
cusj-5637	112	4	integrated	integrate	VERB
cusj-5637	112	5	density	density	NOUN
cusj-5637	112	6	of	of	ADP
cusj-5637	112	7	cells	cell	NOUN
cusj-5637	112	8	incubated	incubate	VERB
cusj-5637	112	9	with	with	ADP
cusj-5637	112	10	the	the	DET
cusj-5637	112	11	di	di	NOUN
cusj-5637	112	12	-	-	PUNCT
cusj-5637	112	13	phosphorylated	phosphorylate	VERB
cusj-5637	112	14	antibody	antibody	NOUN
cusj-5637	112	15	,	,	PUNCT
cusj-5637	112	16	the	the	DET
cusj-5637	112	17	results	result	NOUN
cusj-5637	112	18	demonstrated	demonstrate	VERB
cusj-5637	112	19	60	60	NUM
cusj-5637	112	20	μm	μm	NUM
cusj-5637	112	21	fasudil	fasudil	NOUN
cusj-5637	112	22	decreased	decrease	VERB
cusj-5637	112	23	phosphorylation	phosphorylation	NOUN
cusj-5637	112	24	to	to	ADP
cusj-5637	112	25	57.9	57.9	NUM
cusj-5637	112	26	%	%	NOUN
cusj-5637	112	27	of	of	ADP
cusj-5637	112	28	the	the	DET
cusj-5637	112	29	control	control	NOUN
cusj-5637	112	30	(	(	PUNCT
cusj-5637	112	31	figure	figure	NOUN
cusj-5637	112	32	4c	4c	NOUN
cusj-5637	112	33	;	;	PUNCT
cusj-5637	112	34	p=0.02	p=0.02	NOUN
cusj-5637	112	35	)	)	PUNCT
cusj-5637	112	36	.	.	PUNCT
cusj-5637	113	1	on	on	ADP
cusj-5637	113	2	the	the	DET
cusj-5637	113	3	other	other	ADJ
cusj-5637	113	4	hand	hand	NOUN
cusj-5637	113	5	,	,	PUNCT
cusj-5637	113	6	50	50	NUM
cusj-5637	113	7	μm	μm	NOUN
cusj-5637	113	8	y-27632	y-27632	PROPN
cusj-5637	113	9	decreased	decrease	VERB
cusj-5637	113	10	phosphorylation	phosphorylation	NOUN
cusj-5637	113	11	to	to	ADP
cusj-5637	113	12	55.82	55.82	NUM
cusj-5637	113	13	%	%	NOUN
cusj-5637	113	14	,	,	PUNCT
cusj-5637	113	15	which	which	PRON
cusj-5637	113	16	was	be	AUX
cusj-5637	113	17	not	not	PART
cusj-5637	113	18	significant	significant	ADJ
cusj-5637	113	19	on	on	ADP
cusj-5637	113	20	a	a	DET
cusj-5637	113	21	paired	pair	VERB
cusj-5637	113	22	ttest	ttest	NOUN
cusj-5637	113	23	(	(	PUNCT
cusj-5637	113	24	p=0.095	p=0.095	VERB
cusj-5637	113	25	;	;	PUNCT
cusj-5637	113	26	figure	figure	VERB
cusj-5637	113	27	4c	4c	NOUN
cusj-5637	113	28	)	)	PUNCT
cusj-5637	113	29	,	,	PUNCT
cusj-5637	113	30	but	but	CCONJ
cusj-5637	113	31	was	be	AUX
cusj-5637	113	32	significant	significant	ADJ
cusj-5637	113	33	on	on	ADP
cusj-5637	113	34	an	an	DET
cusj-5637	113	35	unpaired	unpaired	ADJ
cusj-5637	113	36	t	t	NOUN
cusj-5637	113	37	-	-	PUNCT
cusj-5637	113	38	test	test	NOUN
cusj-5637	113	39	(	(	PUNCT
cusj-5637	113	40	p=0.039	p=0.039	NOUN
cusj-5637	113	41	)	)	PUNCT
cusj-5637	113	42	.	.	PUNCT
cusj-5637	114	1	fasudil	fasudil	NOUN
cusj-5637	114	2	,	,	PUNCT
cusj-5637	114	3	therefore	therefore	ADV
cusj-5637	114	4	,	,	PUNCT
cusj-5637	114	5	effectively	effectively	ADV
cusj-5637	114	6	decreases	decrease	VERB
cusj-5637	114	7	the	the	DET
cusj-5637	114	8	monoand	monoand	NOUN
cusj-5637	114	9	diphosphorylation	diphosphorylation	NOUN
cusj-5637	114	10	of	of	ADP
cusj-5637	114	11	the	the	DET
cusj-5637	114	12	rlcs	rlcs	NOUN
cusj-5637	114	13	.	.	PUNCT
cusj-5637	115	1	discussion	discussion	NOUN
cusj-5637	115	2	through	through	ADP
cusj-5637	115	3	the	the	DET
cusj-5637	115	4	various	various	ADJ
cusj-5637	115	5	transwell	transwell	NOUN
cusj-5637	115	6	migration	migration	NOUN
cusj-5637	115	7	assays	assay	NOUN
cusj-5637	116	1	,	,	PUNCT
cusj-5637	116	2	the	the	DET
cusj-5637	116	3	results	result	NOUN
cusj-5637	116	4	indicate	indicate	VERB
cusj-5637	116	5	that	that	SCONJ
cusj-5637	116	6	chemokinetic	chemokinetic	ADJ
cusj-5637	116	7	motility	motility	NOUN
cusj-5637	116	8	is	be	AUX
cusj-5637	116	9	indeed	indeed	ADV
cusj-5637	116	10	inhibited	inhibit	VERB
cusj-5637	116	11	,	,	PUNCT
cusj-5637	116	12	though	though	SCONJ
cusj-5637	116	13	not	not	PART
cusj-5637	116	14	completely	completely	ADV
cusj-5637	116	15	abolished	abolish	VERB
cusj-5637	116	16	,	,	PUNCT
cusj-5637	116	17	when	when	SCONJ
cusj-5637	116	18	glioma	glioma	NOUN
cusj-5637	116	19	cells	cell	NOUN
cusj-5637	116	20	are	be	AUX
cusj-5637	116	21	treated	treat	VERB
cusj-5637	116	22	with	with	ADP
cusj-5637	116	23	100	100	NUM
cusj-5637	116	24	μm	μm	NUM
cusj-5637	116	25	fasudil	fasudil	NOUN
cusj-5637	116	26	.	.	PUNCT
cusj-5637	117	1	these	these	DET
cusj-5637	117	2	results	result	NOUN
cusj-5637	117	3	do	do	AUX
cusj-5637	117	4	yield	yield	VERB
cusj-5637	117	5	promising	promising	ADJ
cusj-5637	117	6	implications	implication	NOUN
cusj-5637	117	7	for	for	ADP
cusj-5637	117	8	fasudil	fasudil	NOUN
cusj-5637	117	9	as	as	SCONJ
cusj-5637	117	10	its	its	PRON
cusj-5637	117	11	efficacy	efficacy	NOUN
cusj-5637	117	12	suggests	suggest	VERB
cusj-5637	117	13	it	it	PRON
cusj-5637	117	14	could	could	AUX
cusj-5637	117	15	make	make	VERB
cusj-5637	117	16	a	a	DET
cusj-5637	117	17	good	good	ADJ
cusj-5637	117	18	inhibitor	inhibitor	NOUN
cusj-5637	117	19	of	of	ADP
cusj-5637	117	20	cell	cell	NOUN
cusj-5637	117	21	migration	migration	NOUN
cusj-5637	117	22	in	in	ADP
cusj-5637	117	23	in	in	ADP
cusj-5637	117	24	vivo	vivo	ADJ
cusj-5637	117	25	studies	study	NOUN
cusj-5637	117	26	as	as	ADV
cusj-5637	117	27	well	well	ADV
cusj-5637	117	28	.	.	PUNCT
cusj-5637	118	1	the	the	DET
cusj-5637	118	2	concentrations	concentration	NOUN
cusj-5637	118	3	used	use	VERB
cusj-5637	118	4	in	in	ADP
cusj-5637	118	5	the	the	DET
cusj-5637	118	6	transwell	transwell	NOUN
cusj-5637	118	7	experiments	experiment	NOUN
cusj-5637	118	8	as	as	ADV
cusj-5637	118	9	well	well	ADV
cusj-5637	118	10	as	as	ADP
cusj-5637	118	11	the	the	DET
cusj-5637	118	12	mtt	mtt	NOUN
cusj-5637	118	13	assay	assay	VERB
cusj-5637	118	14	can	can	AUX
cusj-5637	118	15	help	help	VERB
cusj-5637	118	16	inform	inform	VERB
cusj-5637	118	17	the	the	DET
cusj-5637	118	18	drug	drug	NOUN
cusj-5637	118	19	dosages	dosage	NOUN
cusj-5637	118	20	that	that	PRON
cusj-5637	118	21	could	could	AUX
cusj-5637	118	22	be	be	AUX
cusj-5637	118	23	administered	administer	VERB
cusj-5637	118	24	to	to	ADP
cusj-5637	118	25	a	a	DET
cusj-5637	118	26	living	live	VERB
cusj-5637	118	27	system	system	NOUN
cusj-5637	118	28	for	for	ADP
cusj-5637	118	29	maximal	maximal	ADJ
cusj-5637	118	30	inhibition	inhibition	NOUN
cusj-5637	118	31	and	and	CCONJ
cusj-5637	118	32	minimal	minimal	ADJ
cusj-5637	118	33	side	side	NOUN
cusj-5637	118	34	effects	effect	NOUN
cusj-5637	118	35	.	.	PUNCT
cusj-5637	119	1	it	it	PRON
cusj-5637	119	2	is	be	AUX
cusj-5637	119	3	surprising	surprising	ADJ
cusj-5637	119	4	,	,	PUNCT
cusj-5637	119	5	however	however	ADV
cusj-5637	119	6	,	,	PUNCT
cusj-5637	119	7	that	that	SCONJ
cusj-5637	119	8	the	the	DET
cusj-5637	119	9	negative	negative	ADJ
cusj-5637	119	10	control	control	NOUN
cusj-5637	119	11	of	of	ADP
cusj-5637	119	12	500	500	NUM
cusj-5637	119	13	μm	μm	NUM
cusj-5637	119	14	y-27632	y-27632	ADV
cusj-5637	119	15	-	-	PUNCT
cusj-5637	119	16	treated	treat	VERB
cusj-5637	119	17	cells	cell	NOUN
cusj-5637	119	18	produced	produce	VERB
cusj-5637	119	19	results	result	NOUN
cusj-5637	119	20	that	that	PRON
cusj-5637	119	21	represented	represent	VERB
cusj-5637	119	22	a	a	DET
cusj-5637	119	23	statistically	statistically	ADV
cusj-5637	119	24	significant	significant	ADJ
cusj-5637	119	25	difference	difference	NOUN
cusj-5637	119	26	from	from	ADP
cusj-5637	119	27	that	that	PRON
cusj-5637	119	28	of	of	ADP
cusj-5637	119	29	fasudil	fasudil	NOUN
cusj-5637	119	30	but	but	CCONJ
cusj-5637	119	31	did	do	AUX
cusj-5637	119	32	not	not	PART
cusj-5637	119	33	represent	represent	VERB
cusj-5637	119	34	a	a	DET
cusj-5637	119	35	large	large	ADJ
cusj-5637	119	36	difference	difference	NOUN
cusj-5637	119	37	even	even	ADV
cusj-5637	119	38	though	though	SCONJ
cusj-5637	119	39	the	the	DET
cusj-5637	119	40	y27632	y27632	PROPN
cusj-5637	119	41	concentration	concentration	NOUN
cusj-5637	119	42	had	have	AUX
cusj-5637	119	43	been	be	AUX
cusj-5637	119	44	purposefully	purposefully	ADV
cusj-5637	119	45	and	and	CCONJ
cusj-5637	119	46	dramatically	dramatically	ADV
cusj-5637	119	47	increased	increase	VERB
cusj-5637	119	48	.	.	PUNCT
cusj-5637	120	1	these	these	DET
cusj-5637	120	2	results	result	NOUN
cusj-5637	120	3	suggest	suggest	VERB
cusj-5637	120	4	that	that	SCONJ
cusj-5637	120	5	even	even	ADV
cusj-5637	120	6	at	at	ADP
cusj-5637	120	7	a	a	DET
cusj-5637	120	8	much	much	ADV
cusj-5637	120	9	higher	high	ADJ
cusj-5637	120	10	concentration	concentration	NOUN
cusj-5637	120	11	of	of	ADP
cusj-5637	120	12	rock	rock	NOUN
cusj-5637	120	13	inhibitors	inhibitor	NOUN
cusj-5637	120	14	,	,	PUNCT
cusj-5637	120	15	glioma	glioma	NOUN
cusj-5637	120	16	cell	cell	NOUN
cusj-5637	120	17	migration	migration	NOUN
cusj-5637	120	18	can	can	AUX
cusj-5637	120	19	not	not	PART
cusj-5637	120	20	be	be	AUX
cusj-5637	120	21	completely	completely	ADV
cusj-5637	120	22	inhibited	inhibit	VERB
cusj-5637	120	23	.	.	PUNCT
cusj-5637	121	1	preliminary	preliminary	ADJ
cusj-5637	121	2	results	result	NOUN
cusj-5637	121	3	of	of	ADP
cusj-5637	121	4	tma	tma	PROPN
cusj-5637	121	5	experiments	experiment	NOUN
cusj-5637	121	6	of	of	ADP
cusj-5637	121	7	cells	cell	NOUN
cusj-5637	121	8	treated	treat	VERB
cusj-5637	121	9	with	with	ADP
cusj-5637	121	10	a	a	DET
cusj-5637	121	11	heightened	heightened	ADJ
cusj-5637	121	12	concentration	concentration	NOUN
cusj-5637	121	13	of	of	ADP
cusj-5637	121	14	680	680	NUM
cusj-5637	121	15	μm	μm	NUM
cusj-5637	121	16	fasudil	fasudil	NOUN
cusj-5637	121	17	corroborate	corroborate	NOUN
cusj-5637	121	18	with	with	ADP
cusj-5637	121	19	this	this	DET
cusj-5637	121	20	finding	finding	NOUN
cusj-5637	121	21	(	(	PUNCT
cusj-5637	121	22	5.5	5.5	NUM
cusj-5637	121	23	%	%	NOUN
cusj-5637	121	24	residual	residual	ADJ
cusj-5637	121	25	migration	migration	NOUN
cusj-5637	121	26	,	,	PUNCT
cusj-5637	121	27	n=1	n=1	PROPN
cusj-5637	121	28	)	)	PUNCT
cusj-5637	121	29	.	.	PUNCT
cusj-5637	122	1	similarly	similarly	ADV
cusj-5637	122	2	,	,	PUNCT
cusj-5637	122	3	the	the	DET
cusj-5637	122	4	ptyb	ptyb	NOUN
cusj-5637	122	5	cells	cell	NOUN
cusj-5637	122	6	stained	stain	VERB
cusj-5637	122	7	with	with	ADP
cusj-5637	122	8	phospho	phospho	ADJ
cusj-5637	122	9	-	-	PUNCT
cusj-5637	122	10	rlc	rlc	PROPN
cusj-5637	122	11	antibodies	antibody	NOUN
cusj-5637	122	12	demonstrated	demonstrate	VERB
cusj-5637	122	13	cells	cell	NOUN
cusj-5637	122	14	treated	treat	VERB
cusj-5637	122	15	with	with	ADP
cusj-5637	122	16	fasudil	fasudil	NOUN
cusj-5637	122	17	or	or	CCONJ
cusj-5637	122	18	y-2763	y-2763	PROPN
cusj-5637	122	19	exhibited	exhibit	VERB
cusj-5637	122	20	a	a	DET
cusj-5637	122	21	lower	low	ADJ
cusj-5637	122	22	level	level	NOUN
cusj-5637	122	23	of	of	ADP
cusj-5637	122	24	total	total	ADJ
cusj-5637	122	25	phosphorylation	phosphorylation	NOUN
cusj-5637	122	26	(	(	PUNCT
cusj-5637	122	27	figure	figure	NOUN
cusj-5637	122	28	4	4	NUM
cusj-5637	122	29	)	)	PUNCT
cusj-5637	122	30	.	.	PUNCT
cusj-5637	123	1	the	the	DET
cusj-5637	123	2	phospho	phospho	PROPN
cusj-5637	123	3	-	-	PUNCT
cusj-5637	123	4	rlc	rlc	PROPN
cusj-5637	123	5	images	image	NOUN
cusj-5637	123	6	also	also	ADV
cusj-5637	123	7	demonstrate	demonstrate	VERB
cusj-5637	123	8	a	a	DET
cusj-5637	123	9	clear	clear	ADJ
cusj-5637	123	10	change	change	NOUN
cusj-5637	123	11	in	in	ADP
cusj-5637	123	12	cell	cell	NOUN
cusj-5637	123	13	morphology	morphology	NOUN
cusj-5637	123	14	after	after	ADP
cusj-5637	123	15	treatment	treatment	NOUN
cusj-5637	123	16	with	with	ADP
cusj-5637	123	17	fasudil	fasudil	NOUN
cusj-5637	123	18	or	or	CCONJ
cusj-5637	123	19	y-27632	y-27632	PROPN
cusj-5637	123	20	.	.	PUNCT
cusj-5637	124	1	cells	cell	NOUN
cusj-5637	124	2	begin	begin	VERB
cusj-5637	124	3	to	to	PART
cusj-5637	124	4	form	form	VERB
cusj-5637	124	5	long	long	ADJ
cusj-5637	124	6	,	,	PUNCT
cusj-5637	124	7	thin	thin	ADJ
cusj-5637	124	8	spindle	spindle	NOUN
cusj-5637	124	9	-	-	PUNCT
cusj-5637	124	10	like	like	ADJ
cusj-5637	124	11	extensions	extension	NOUN
cusj-5637	124	12	and	and	CCONJ
cusj-5637	124	13	lose	lose	VERB
cusj-5637	124	14	their	their	PRON
cusj-5637	124	15	more	more	ADV
cusj-5637	124	16	rotund	rotund	ADJ
cusj-5637	124	17	cell	cell	NOUN
cusj-5637	124	18	shape	shape	NOUN
cusj-5637	124	19	(	(	PUNCT
cusj-5637	124	20	figure	figure	NOUN
cusj-5637	124	21	4	4	NUM
cusj-5637	124	22	)	)	PUNCT
cusj-5637	124	23	.	.	PUNCT
cusj-5637	125	1	this	this	PRON
cusj-5637	125	2	suggests	suggest	VERB
cusj-5637	125	3	that	that	SCONJ
cusj-5637	125	4	decrease	decrease	NOUN
cusj-5637	125	5	in	in	ADP
cusj-5637	125	6	nmii	nmii	PROPN
cusj-5637	125	7	rlc	rlc	PROPN
cusj-5637	125	8	phosphorylation	phosphorylation	PROPN
cusj-5637	125	9	and	and	CCONJ
cusj-5637	125	10	the	the	DET
cusj-5637	125	11	decrease	decrease	NOUN
cusj-5637	125	12	in	in	ADP
cusj-5637	125	13	nmii	nmii	NOUN
cusj-5637	125	14	activity	activity	NOUN
cusj-5637	125	15	is	be	AUX
cusj-5637	125	16	qualitatively	qualitatively	ADV
cusj-5637	125	17	related	relate	VERB
cusj-5637	125	18	to	to	ADP
cusj-5637	125	19	the	the	DET
cusj-5637	125	20	cytoskeleton	cytoskeleton	NOUN
cusj-5637	125	21	structure	structure	NOUN
cusj-5637	125	22	of	of	ADP
cusj-5637	125	23	glioma	glioma	NOUN
cusj-5637	125	24	cells	cell	NOUN
cusj-5637	125	25	.	.	PUNCT
cusj-5637	126	1	in	in	ADP
cusj-5637	126	2	addition	addition	NOUN
cusj-5637	126	3	,	,	PUNCT
cusj-5637	126	4	the	the	DET
cusj-5637	126	5	nmii	nmii	NOUN
cusj-5637	126	6	activity	activity	NOUN
cusj-5637	126	7	decrease	decrease	NOUN
cusj-5637	126	8	potentially	potentially	ADV
cusj-5637	126	9	is	be	AUX
cusj-5637	126	10	related	relate	VERB
cusj-5637	126	11	to	to	ADP
cusj-5637	126	12	the	the	DET
cusj-5637	126	13	decrease	decrease	NOUN
cusj-5637	126	14	in	in	ADP
cusj-5637	126	15	focal	focal	ADJ
cusj-5637	126	16	adhesions	adhesion	NOUN
cusj-5637	126	17	and	and	CCONJ
cusj-5637	126	18	stress	stress	NOUN
cusj-5637	126	19	fiber	fiber	NOUN
cusj-5637	126	20	formation	formation	NOUN
cusj-5637	126	21	,	,	PUNCT
cusj-5637	126	22	as	as	SCONJ
cusj-5637	126	23	detailed	detailed	ADJ
cusj-5637	126	24	in	in	ADP
cusj-5637	126	25	other	other	ADJ
cusj-5637	126	26	studies	study	NOUN
cusj-5637	126	27	[	[	X
cusj-5637	126	28	2	2	NUM
cusj-5637	126	29	]	]	PUNCT
cusj-5637	126	30	.	.	PUNCT
cusj-5637	127	1	in	in	ADP
cusj-5637	127	2	images	image	NOUN
cusj-5637	127	3	of	of	ADP
cusj-5637	127	4	cells	cell	NOUN
cusj-5637	127	5	stained	stain	VERB
cusj-5637	127	6	with	with	ADP
cusj-5637	127	7	pt18ps19	pt18ps19	PROPN
cusj-5637	127	8	,	,	PUNCT
cusj-5637	127	9	however	however	ADV
cusj-5637	127	10	,	,	PUNCT
cusj-5637	127	11	there	there	PRON
cusj-5637	127	12	was	be	VERB
cusj-5637	127	13	evidence	evidence	NOUN
cusj-5637	127	14	of	of	ADP
cusj-5637	127	15	non	non	ADJ
cusj-5637	127	16	-	-	ADJ
cusj-5637	127	17	specific	specific	ADJ
cusj-5637	127	18	nuclear	nuclear	ADJ
cusj-5637	127	19	staining	staining	NOUN
cusj-5637	127	20	that	that	SCONJ
cusj-5637	127	21	most	most	ADV
cusj-5637	127	22	likely	likely	ADV
cusj-5637	127	23	overestimated	overestimate	VERB
cusj-5637	127	24	the	the	DET
cusj-5637	127	25	phosphorylation	phosphorylation	NOUN
cusj-5637	127	26	signal	signal	NOUN
cusj-5637	127	27	during	during	ADP
cusj-5637	127	28	quantification	quantification	NOUN
cusj-5637	127	29	.	.	PUNCT
cusj-5637	128	1	future	future	ADJ
cusj-5637	128	2	experiments	experiment	NOUN
cusj-5637	128	3	can	can	AUX
cusj-5637	128	4	be	be	AUX
cusj-5637	128	5	done	do	VERB
cusj-5637	128	6	to	to	PART
cusj-5637	128	7	corroborate	corroborate	VERB
cusj-5637	128	8	the	the	DET
cusj-5637	128	9	results	result	NOUN
cusj-5637	128	10	shown	show	VERB
cusj-5637	128	11	in	in	ADP
cusj-5637	128	12	figure	figure	NOUN
cusj-5637	128	13	4	4	NUM
cusj-5637	128	14	by	by	ADP
cusj-5637	128	15	measuring	measure	VERB
cusj-5637	128	16	phosphorylation	phosphorylation	NOUN
cusj-5637	128	17	levels	level	NOUN
cusj-5637	128	18	through	through	ADP
cusj-5637	128	19	other	other	ADJ
cusj-5637	128	20	methods	method	NOUN
cusj-5637	128	21	such	such	ADJ
cusj-5637	128	22	as	as	ADP
cusj-5637	128	23	western	western	ADJ
cusj-5637	128	24	blots	blot	NOUN
cusj-5637	128	25	using	use	VERB
cusj-5637	128	26	antibodies	antibody	NOUN
cusj-5637	128	27	that	that	PRON
cusj-5637	128	28	can	can	AUX
cusj-5637	128	29	detect	detect	VERB
cusj-5637	128	30	monoor	monoor	ADJ
cusj-5637	128	31	di	di	NOUN
cusj-5637	128	32	-	-	NOUN
cusj-5637	128	33	phosphorylation	phosphorylation	NOUN
cusj-5637	128	34	.	.	PUNCT
cusj-5637	129	1	decreased	decrease	VERB
cusj-5637	129	2	rock	rock	NOUN
cusj-5637	129	3	activity	activity	NOUN
cusj-5637	129	4	after	after	ADP
cusj-5637	129	5	treatment	treatment	NOUN
cusj-5637	129	6	with	with	ADP
cusj-5637	129	7	fasudil	fasudil	NOUN
cusj-5637	129	8	could	could	AUX
cusj-5637	129	9	also	also	ADV
cusj-5637	129	10	be	be	AUX
cusj-5637	129	11	assessed	assess	VERB
cusj-5637	129	12	through	through	ADP
cusj-5637	129	13	western	western	ADJ
cusj-5637	129	14	blots	blot	NOUN
cusj-5637	129	15	with	with	ADP
cusj-5637	129	16	a	a	DET
cusj-5637	129	17	rock	rock	NOUN
cusj-5637	129	18	antibody	antibody	NOUN
cusj-5637	129	19	like	like	ADP
cusj-5637	129	20	ser1366	ser1366	ADJ
cusj-5637	129	21	,	,	PUNCT
cusj-5637	129	22	antibodies	antibodie	VERB
cusj-5637	129	23	for	for	ADP
cusj-5637	129	24	an	an	DET
cusj-5637	129	25	alternate	alternate	ADJ
cusj-5637	129	26	substrate	substrate	NOUN
cusj-5637	129	27	of	of	ADP
cusj-5637	129	28	rock	rock	NOUN
cusj-5637	129	29	such	such	ADJ
cusj-5637	129	30	as	as	ADP
cusj-5637	129	31	lim	lim	PROPN
cusj-5637	129	32	kinase	kinase	PROPN
cusj-5637	129	33	,	,	PUNCT
cusj-5637	129	34	through	through	SCONJ
cusj-5637	129	35	a	a	DET
cusj-5637	129	36	quantitative	quantitative	ADJ
cusj-5637	129	37	rock	rock	NOUN
cusj-5637	129	38	activity	activity	NOUN
cusj-5637	129	39	assay	assay	VERB
cusj-5637	129	40	[	[	X
cusj-5637	129	41	3	3	NUM
cusj-5637	129	42	]	]	PUNCT
cusj-5637	129	43	.	.	PUNCT
cusj-5637	130	1	it	it	PRON
cusj-5637	130	2	is	be	AUX
cusj-5637	130	3	also	also	ADV
cusj-5637	130	4	possible	possible	ADJ
cusj-5637	130	5	,	,	PUNCT
cusj-5637	130	6	however	however	ADV
cusj-5637	130	7	,	,	PUNCT
cusj-5637	130	8	that	that	SCONJ
cusj-5637	130	9	the	the	DET
cusj-5637	130	10	residual	residual	ADJ
cusj-5637	130	11	phosphorylation	phosphorylation	NOUN
cusj-5637	130	12	and	and	CCONJ
cusj-5637	130	13	migration	migration	NOUN
cusj-5637	130	14	across	across	ADP
cusj-5637	130	15	transfilters	transfilter	NOUN
cusj-5637	130	16	is	be	AUX
cusj-5637	130	17	due	due	ADJ
cusj-5637	130	18	to	to	ADP
cusj-5637	130	19	rlc	rlc	PROPN
cusj-5637	130	20	phosphorylation	phosphorylation	NOUN
cusj-5637	130	21	from	from	ADP
cusj-5637	130	22	biology	biology	PROPN
cusj-5637	130	23	columbia	columbia	PROPN
cusj-5637	130	24	undergraduate	undergraduate	PROPN
cusj-5637	130	25	science	science	PROPN
cusj-5637	130	26	journal	journal	PROPN
cusj-5637	130	27	open	open	ADJ
cusj-5637	130	28	-	-	PUNCT
cusj-5637	130	29	access	access	NOUN
cusj-5637	130	30	publication	publication	NOUN
cusj-5637	130	31	|	|	NOUN
cusj-5637	130	32	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5637	130	33	spring	spring	NOUN
cusj-5637	130	34	2014	2014	NUM
cusj-5637	131	1	|	|	ADV
cusj-5637	131	2	volume	volume	NOUN
cusj-5637	131	3	8	8	NUM
cusj-5637	131	4	9	9	NUM
cusj-5637	131	5	other	other	ADJ
cusj-5637	131	6	pathways	pathway	NOUN
cusj-5637	131	7	.	.	PUNCT
cusj-5637	132	1	one	one	NUM
cusj-5637	132	2	important	important	ADJ
cusj-5637	132	3	pathway	pathway	NOUN
cusj-5637	132	4	to	to	PART
cusj-5637	132	5	consider	consider	VERB
cusj-5637	132	6	is	be	AUX
cusj-5637	132	7	the	the	DET
cusj-5637	132	8	mlck	mlck	NOUN
cusj-5637	132	9	mediated	mediate	VERB
cusj-5637	132	10	route	route	NOUN
cusj-5637	132	11	,	,	PUNCT
cusj-5637	132	12	which	which	PRON
cusj-5637	132	13	is	be	AUX
cusj-5637	132	14	also	also	ADV
cusj-5637	132	15	known	know	VERB
cusj-5637	132	16	to	to	PART
cusj-5637	132	17	phosphorylate	phosphorylate	VERB
cusj-5637	132	18	rlcs	rlcs	NOUN
cusj-5637	132	19	at	at	ADP
cusj-5637	132	20	the	the	DET
cusj-5637	132	21	same	same	ADJ
cusj-5637	132	22	sites	site	NOUN
cusj-5637	132	23	as	as	ADP
cusj-5637	132	24	rock	rock	NOUN
cusj-5637	132	25	.	.	PUNCT
cusj-5637	133	1	this	this	PRON
cusj-5637	133	2	could	could	AUX
cusj-5637	133	3	be	be	AUX
cusj-5637	133	4	tested	test	VERB
cusj-5637	133	5	by	by	ADP
cusj-5637	133	6	assessing	assess	VERB
cusj-5637	133	7	phosphorylation	phosphorylation	NOUN
cusj-5637	133	8	and	and	CCONJ
cusj-5637	133	9	migration	migration	NOUN
cusj-5637	133	10	after	after	ADP
cusj-5637	133	11	treating	treat	VERB
cusj-5637	133	12	cells	cell	NOUN
cusj-5637	133	13	with	with	ADP
cusj-5637	133	14	both	both	DET
cusj-5637	133	15	fasudil	fasudil	NOUN
cusj-5637	133	16	as	as	ADV
cusj-5637	133	17	well	well	ADV
cusj-5637	133	18	as	as	ADP
cusj-5637	133	19	an	an	DET
cusj-5637	133	20	mclk	mclk	NOUN
cusj-5637	133	21	inhibitor	inhibitor	NOUN
cusj-5637	133	22	such	such	ADJ
cusj-5637	133	23	as	as	ADP
cusj-5637	133	24	ml-7	ml-7	NOUN
cusj-5637	133	25	[	[	X
cusj-5637	133	26	7	7	NUM
cusj-5637	133	27	]	]	PUNCT
cusj-5637	133	28	.	.	PUNCT
cusj-5637	134	1	finally	finally	ADV
cusj-5637	134	2	,	,	PUNCT
cusj-5637	134	3	it	it	PRON
cusj-5637	134	4	is	be	AUX
cusj-5637	134	5	important	important	ADJ
cusj-5637	134	6	to	to	PART
cusj-5637	134	7	note	note	VERB
cusj-5637	134	8	that	that	SCONJ
cusj-5637	134	9	though	though	SCONJ
cusj-5637	134	10	fasudil	fasudil	NOUN
cusj-5637	134	11	is	be	AUX
cusj-5637	134	12	an	an	DET
cusj-5637	134	13	effective	effective	ADJ
cusj-5637	134	14	drug	drug	NOUN
cusj-5637	134	15	target	target	NOUN
cusj-5637	134	16	in	in	ADP
cusj-5637	134	17	short	short	ADJ
cusj-5637	134	18	-	-	PUNCT
cusj-5637	134	19	term	term	NOUN
cusj-5637	134	20	or	or	CCONJ
cusj-5637	134	21	acute	acute	ADJ
cusj-5637	134	22	treatment	treatment	NOUN
cusj-5637	134	23	,	,	PUNCT
cusj-5637	134	24	we	we	PRON
cusj-5637	134	25	still	still	ADV
cusj-5637	134	26	do	do	AUX
cusj-5637	134	27	not	not	PART
cusj-5637	134	28	know	know	VERB
cusj-5637	134	29	if	if	SCONJ
cusj-5637	134	30	it	it	PRON
cusj-5637	134	31	will	will	AUX
cusj-5637	134	32	work	work	VERB
cusj-5637	134	33	after	after	ADP
cusj-5637	134	34	a	a	DET
cusj-5637	134	35	more	more	ADV
cusj-5637	134	36	long	long	ADJ
cusj-5637	134	37	-	-	PUNCT
cusj-5637	134	38	term	term	NOUN
cusj-5637	134	39	treatment	treatment	NOUN
cusj-5637	134	40	.	.	PUNCT
cusj-5637	135	1	it	it	PRON
cusj-5637	135	2	is	be	AUX
cusj-5637	135	3	possible	possible	ADJ
cusj-5637	135	4	that	that	SCONJ
cusj-5637	135	5	cells	cell	NOUN
cusj-5637	135	6	will	will	AUX
cusj-5637	135	7	eventually	eventually	ADV
cusj-5637	135	8	compensate	compensate	VERB
cusj-5637	135	9	for	for	ADP
cusj-5637	135	10	rock	rock	NOUN
cusj-5637	135	11	inhibition	inhibition	NOUN
cusj-5637	135	12	.	.	PUNCT
cusj-5637	136	1	this	this	DET
cusj-5637	136	2	information	information	NOUN
cusj-5637	136	3	will	will	AUX
cusj-5637	136	4	be	be	AUX
cusj-5637	136	5	particularly	particularly	ADV
cusj-5637	136	6	important	important	ADJ
cusj-5637	136	7	for	for	ADP
cusj-5637	136	8	future	future	NOUN
cusj-5637	136	9	in	in	ADP
cusj-5637	136	10	vivo	vivo	ADJ
cusj-5637	136	11	studies	study	NOUN
cusj-5637	136	12	or	or	CCONJ
cusj-5637	136	13	clinical	clinical	ADJ
cusj-5637	136	14	trials	trial	NOUN
cusj-5637	136	15	because	because	SCONJ
cusj-5637	136	16	it	it	PRON
cusj-5637	136	17	can	can	AUX
cusj-5637	136	18	greatly	greatly	ADV
cusj-5637	136	19	influence	influence	VERB
cusj-5637	136	20	how	how	SCONJ
cusj-5637	136	21	the	the	DET
cusj-5637	136	22	drug	drug	NOUN
cusj-5637	136	23	is	be	AUX
cusj-5637	136	24	delivered	deliver	VERB
cusj-5637	136	25	,	,	PUNCT
cusj-5637	136	26	how	how	SCONJ
cusj-5637	136	27	often	often	ADV
cusj-5637	136	28	it	it	PRON
cusj-5637	136	29	is	be	AUX
cusj-5637	136	30	delivered	deliver	VERB
cusj-5637	136	31	,	,	PUNCT
cusj-5637	136	32	or	or	CCONJ
cusj-5637	136	33	whether	whether	SCONJ
cusj-5637	136	34	it	it	PRON
cusj-5637	136	35	should	should	AUX
cusj-5637	136	36	be	be	AUX
cusj-5637	136	37	administered	administer	VERB
cusj-5637	136	38	along	along	ADP
cusj-5637	136	39	with	with	ADP
cusj-5637	136	40	another	another	DET
cusj-5637	136	41	drug	drug	NOUN
cusj-5637	136	42	.	.	PUNCT
cusj-5637	137	1	subsequent	subsequent	ADJ
cusj-5637	137	2	experiments	experiment	NOUN
cusj-5637	137	3	can	can	AUX
cusj-5637	137	4	be	be	AUX
cusj-5637	137	5	done	do	VERB
cusj-5637	137	6	to	to	PART
cusj-5637	137	7	test	test	VERB
cusj-5637	137	8	motility	motility	NOUN
cusj-5637	137	9	of	of	ADP
cusj-5637	137	10	glioma	glioma	NOUN
cusj-5637	137	11	cells	cell	NOUN
cusj-5637	137	12	after	after	ADP
cusj-5637	137	13	prolonged	prolong	VERB
cusj-5637	137	14	periods	period	NOUN
cusj-5637	137	15	of	of	ADP
cusj-5637	137	16	treatment	treatment	NOUN
cusj-5637	137	17	with	with	ADP
cusj-5637	137	18	fasudil	fasudil	NOUN
cusj-5637	137	19	.	.	PUNCT
cusj-5637	138	1	further	further	ADJ
cusj-5637	138	2	experiments	experiment	NOUN
cusj-5637	138	3	in	in	ADP
cusj-5637	138	4	motility	motility	NOUN
cusj-5637	138	5	could	could	AUX
cusj-5637	138	6	also	also	ADV
cusj-5637	138	7	be	be	AUX
cusj-5637	138	8	conducted	conduct	VERB
cusj-5637	138	9	with	with	ADP
cusj-5637	138	10	fasudil	fasudil	NOUN
cusj-5637	138	11	that	that	PRON
cusj-5637	138	12	has	have	AUX
cusj-5637	138	13	been	be	AUX
cusj-5637	138	14	incubated	incubate	VERB
cusj-5637	138	15	for	for	ADP
cusj-5637	138	16	periods	period	NOUN
cusj-5637	138	17	of	of	ADP
cusj-5637	138	18	time	time	NOUN
cusj-5637	138	19	at	at	ADP
cusj-5637	138	20	biological	biological	ADJ
cusj-5637	138	21	temperatures	temperature	NOUN
cusj-5637	138	22	to	to	PART
cusj-5637	138	23	test	test	VERB
cusj-5637	138	24	the	the	DET
cusj-5637	138	25	biostability	biostability	NOUN
cusj-5637	138	26	of	of	ADP
cusj-5637	138	27	the	the	DET
cusj-5637	138	28	drug	drug	NOUN
cusj-5637	138	29	and	and	CCONJ
cusj-5637	138	30	to	to	PART
cusj-5637	138	31	see	see	VERB
cusj-5637	138	32	if	if	SCONJ
cusj-5637	138	33	its	its	PRON
cusj-5637	138	34	efficacy	efficacy	NOUN
cusj-5637	138	35	decreases	decrease	VERB
cusj-5637	138	36	with	with	ADP
cusj-5637	138	37	prolonged	prolonged	ADJ
cusj-5637	138	38	incubation	incubation	NOUN
cusj-5637	138	39	.	.	PUNCT
cusj-5637	139	1	these	these	DET
cusj-5637	139	2	experiments	experiment	NOUN
cusj-5637	139	3	also	also	ADV
cusj-5637	139	4	have	have	VERB
cusj-5637	139	5	very	very	ADV
cusj-5637	139	6	important	important	ADJ
cusj-5637	139	7	implications	implication	NOUN
cusj-5637	139	8	for	for	ADP
cusj-5637	139	9	future	future	NOUN
cusj-5637	139	10	in	in	ADP
cusj-5637	139	11	vivo	vivo	ADJ
cusj-5637	139	12	or	or	CCONJ
cusj-5637	139	13	clinical	clinical	ADJ
cusj-5637	139	14	studies	study	NOUN
cusj-5637	139	15	.	.	PUNCT
cusj-5637	140	1	thus	thus	ADV
cusj-5637	140	2	,	,	PUNCT
cusj-5637	140	3	though	though	SCONJ
cusj-5637	140	4	fasudil	fasudil	NOUN
cusj-5637	140	5	is	be	AUX
cusj-5637	140	6	a	a	DET
cusj-5637	140	7	very	very	ADV
cusj-5637	140	8	promising	promising	ADJ
cusj-5637	140	9	drug	drug	NOUN
cusj-5637	140	10	,	,	PUNCT
cusj-5637	140	11	more	more	ADJ
cusj-5637	140	12	work	work	NOUN
cusj-5637	140	13	must	must	AUX
cusj-5637	140	14	be	be	AUX
cusj-5637	140	15	done	do	VERB
cusj-5637	140	16	in	in	ADP
cusj-5637	140	17	order	order	NOUN
cusj-5637	140	18	to	to	PART
cusj-5637	140	19	elucidate	elucidate	VERB
cusj-5637	140	20	the	the	DET
cusj-5637	140	21	prolonged	prolonged	ADJ
cusj-5637	140	22	effects	effect	NOUN
cusj-5637	140	23	of	of	ADP
cusj-5637	140	24	fasudil	fasudil	NOUN
cusj-5637	140	25	and	and	CCONJ
cusj-5637	140	26	determine	determine	VERB
cusj-5637	140	27	the	the	DET
cusj-5637	140	28	cell	cell	NOUN
cusj-5637	140	29	’s	’s	PART
cusj-5637	140	30	precise	precise	ADJ
cusj-5637	140	31	response	response	NOUN
cusj-5637	140	32	to	to	ADP
cusj-5637	140	33	the	the	DET
cusj-5637	140	34	drug	drug	NOUN
cusj-5637	140	35	and	and	CCONJ
cusj-5637	140	36	its	its	PRON
cusj-5637	140	37	potential	potential	NOUN
cusj-5637	140	38	as	as	ADP
cusj-5637	140	39	a	a	DET
cusj-5637	140	40	cancer	cancer	NOUN
cusj-5637	140	41	drug	drug	NOUN
cusj-5637	140	42	in	in	ADP
cusj-5637	140	43	living	living	NOUN
cusj-5637	140	44	systems	system	NOUN
cusj-5637	140	45	.	.	PUNCT
cusj-5637	141	1	references	reference	NOUN
cusj-5637	141	2	1	1	NUM
cusj-5637	141	3	.	.	PUNCT
cusj-5637	141	4	beadle	beadle	PROPN
cusj-5637	141	5	,	,	PUNCT
cusj-5637	141	6	c.	c.	PROPN
cusj-5637	141	7	,	,	PUNCT
cusj-5637	141	8	m.	m.	NOUN
cusj-5637	141	9	c.	c.	PROPN
cusj-5637	141	10	assanah	assanah	PROPN
cusj-5637	141	11	,	,	PUNCT
cusj-5637	141	12	p.	p.	PROPN
cusj-5637	141	13	monzo	monzo	PROPN
cusj-5637	141	14	,	,	PUNCT
cusj-5637	141	15	r.	r.	PROPN
cusj-5637	141	16	vallee	vallee	PROPN
cusj-5637	141	17	,	,	PUNCT
cusj-5637	141	18	s.	s.	PROPN
cusj-5637	141	19	s.	s.	PROPN
cusj-5637	141	20	rosenfeld	rosenfeld	PROPN
cusj-5637	141	21	,	,	PUNCT
cusj-5637	141	22	and	and	CCONJ
cusj-5637	141	23	p.	p.	PROPN
cusj-5637	141	24	canoll	canoll	NOUN
cusj-5637	141	25	(	(	PUNCT
cusj-5637	141	26	2008	2008	NUM
cusj-5637	141	27	)	)	PUNCT
cusj-5637	141	28	.	.	PUNCT
cusj-5637	142	1	"	"	PUNCT
cusj-5637	142	2	the	the	DET
cusj-5637	142	3	role	role	NOUN
cusj-5637	142	4	of	of	ADP
cusj-5637	142	5	myosin	myosin	PROPN
cusj-5637	142	6	ii	ii	PROPN
cusj-5637	142	7	in	in	ADP
cusj-5637	142	8	glioma	glioma	ADJ
cusj-5637	142	9	invasion	invasion	NOUN
cusj-5637	142	10	of	of	ADP
cusj-5637	142	11	the	the	DET
cusj-5637	142	12	brain	brain	NOUN
cusj-5637	142	13	.	.	PUNCT
cusj-5637	142	14	"	"	PUNCT
cusj-5637	143	1	mol	mol	ADP
cusj-5637	143	2	biol	biol	PROPN
cusj-5637	143	3	cell	cell	NOUN
cusj-5637	143	4	19	19	NUM
cusj-5637	143	5	,	,	PUNCT
cusj-5637	143	6	no	no	INTJ
cusj-5637	143	7	.	.	NOUN
cusj-5637	143	8	8	8	NUM
cusj-5637	143	9	:	:	PUNCT
cusj-5637	143	10	3357	3357	NUM
cusj-5637	143	11	-	-	SYM
cusj-5637	143	12	68	68	NUM
cusj-5637	143	13	.	.	NOUN
cusj-5637	143	14	2	2	NUM
cusj-5637	143	15	.	.	NUM
cusj-5637	143	16	chihara	chihara	PROPN
cusj-5637	143	17	,	,	PUNCT
cusj-5637	143	18	k.	k.	PROPN
cusj-5637	143	19	,	,	PUNCT
cusj-5637	143	20	m.	m.	NOUN
cusj-5637	143	21	amano	amano	PROPN
cusj-5637	143	22	,	,	PUNCT
cusj-5637	143	23	n.	n.	PROPN
cusj-5637	143	24	nakamura	nakamura	PROPN
cusj-5637	143	25	,	,	PUNCT
cusj-5637	143	26	t.	t.	PROPN
cusj-5637	143	27	yano	yano	PROPN
cusj-5637	143	28	,	,	PUNCT
cusj-5637	143	29	m.	m.	NOUN
cusj-5637	143	30	shibata	shibata	PROPN
cusj-5637	143	31	,	,	PUNCT
cusj-5637	143	32	t.	t.	NOUN
cusj-5637	143	33	tokui	tokui	PROPN
cusj-5637	143	34	,	,	PUNCT
cusj-5637	143	35	h.	h.	PROPN
cusj-5637	143	36	ichikawa	ichikawa	PROPN
cusj-5637	143	37	,	,	PUNCT
cusj-5637	143	38	r.	r.	PROPN
cusj-5637	143	39	ikebe	ikebe	PROPN
cusj-5637	143	40	,	,	PUNCT
cusj-5637	143	41	m.	m.	NOUN
cusj-5637	143	42	ikebe	ikebe	NOUN
cusj-5637	143	43	,	,	PUNCT
cusj-5637	143	44	and	and	CCONJ
cusj-5637	143	45	k.	k.	PROPN
cusj-5637	143	46	kaibuchi	kaibuchi	PROPN
cusj-5637	143	47	(	(	PUNCT
cusj-5637	143	48	1997	1997	NUM
cusj-5637	143	49	)	)	PUNCT
cusj-5637	143	50	.	.	PUNCT
cusj-5637	144	1	cytoskeletal	cytoskeletal	ADJ
cusj-5637	144	2	rearrangements	rearrangement	NOUN
cusj-5637	144	3	and	and	CCONJ
cusj-5637	144	4	transcriptional	transcriptional	ADJ
cusj-5637	144	5	activation	activation	NOUN
cusj-5637	144	6	of	of	ADP
cusj-5637	144	7	c	c	NOUN
cusj-5637	144	8	-	-	PUNCT
cusj-5637	144	9	fos	fos	VERB
cusj-5637	144	10	serum	serum	NOUN
cusj-5637	144	11	response	response	NOUN
cusj-5637	144	12	element	element	NOUN
cusj-5637	144	13	by	by	ADP
cusj-5637	144	14	rho	rho	ADJ
cusj-5637	144	15	-	-	PUNCT
cusj-5637	144	16	kinase	kinase	NOUN
cusj-5637	144	17	.	.	PUNCT
cusj-5637	145	1	j.	j.	PROPN
cusj-5637	145	2	biol	biol	PROPN
cusj-5637	145	3	.	.	PUNCT
cusj-5637	146	1	chem	chem	NOUN
cusj-5637	146	2	.	.	PUNCT
cusj-5637	147	1	272:25121	272:25121	NUM
cusj-5637	147	2	-	-	SYM
cusj-5637	147	3	25127	25127	NUM
cusj-5637	147	4	.	.	PUNCT
cusj-5637	148	1	3	3	X
cusj-5637	148	2	.	.	X
cusj-5637	148	3	chuang	chuang	PROPN
cusj-5637	148	4	,	,	PUNCT
cusj-5637	148	5	h.	h.	PROPN
cusj-5637	148	6	h.	h.	PROPN
cusj-5637	148	7	,	,	PUNCT
cusj-5637	148	8	c.	c.	PROPN
cusj-5637	148	9	h.	h.	PROPN
cusj-5637	148	10	yang	yang	PROPN
cusj-5637	148	11	,	,	PUNCT
cusj-5637	148	12	y.	y.	PROPN
cusj-5637	148	13	g.	g.	PROPN
cusj-5637	148	14	tsay	tsay	PROPN
cusj-5637	148	15	,	,	PUNCT
cusj-5637	148	16	c.	c.	PROPN
cusj-5637	148	17	y.	y.	PROPN
cusj-5637	148	18	hsu	hsu	PROPN
cusj-5637	148	19	,	,	PUNCT
cusj-5637	148	20	l.	l.	PROPN
cusj-5637	148	21	m.	m.	PROPN
cusj-5637	148	22	tseng	tseng	PROPN
cusj-5637	148	23	,	,	PUNCT
cusj-5637	148	24	z.	z.	PROPN
cusj-5637	148	25	f.	f.	PROPN
cusj-5637	148	26	chang	chang	PROPN
cusj-5637	148	27	,	,	PUNCT
cusj-5637	148	28	and	and	CCONJ
cusj-5637	148	29	h.	h.	PROPN
cusj-5637	148	30	h.	h.	PROPN
cusj-5637	148	31	lee	lee	PROPN
cusj-5637	148	32	.	.	PUNCT
cusj-5637	149	1	"	"	PUNCT
cusj-5637	149	2	rock	rock	PROPN
cusj-5637	149	3	ii	ii	PROPN
cusj-5637	149	4	ser1366	ser1366	PROPN
cusj-5637	149	5	phosphorylation	phosphorylation	NOUN
cusj-5637	149	6	reflects	reflect	VERB
cusj-5637	149	7	the	the	DET
cusj-5637	149	8	activation	activation	NOUN
cusj-5637	149	9	status	status	NOUN
cusj-5637	149	10	.	.	PUNCT
cusj-5637	149	11	"	"	PUNCT
cusj-5637	150	1	biochem	biochem	PROPN
cusj-5637	150	2	j	j	PROPN
cusj-5637	150	3	443	443	NUM
cusj-5637	150	4	,	,	PUNCT
cusj-5637	150	5	no	no	INTJ
cusj-5637	150	6	.	.	NOUN
cusj-5637	150	7	1	1	NUM
cusj-5637	150	8	(	(	PUNCT
cusj-5637	150	9	apr	apr	PROPN
cusj-5637	150	10	1	1	NUM
cusj-5637	150	11	2012	2012	NUM
cusj-5637	150	12	):	):	PUNCT
cusj-5637	150	13	145	145	NUM
cusj-5637	150	14	-	-	SYM
cusj-5637	150	15	51	51	NUM
cusj-5637	150	16	.	.	PUNCT
cusj-5637	150	17	4	4	NUM
cusj-5637	150	18	.	.	X
cusj-5637	151	1	farin	farin	PROPN
cusj-5637	151	2	,	,	PUNCT
cusj-5637	151	3	a.	a.	PROPN
cusj-5637	151	4	,	,	PUNCT
cusj-5637	151	5	s.	s.	PROPN
cusj-5637	151	6	o.	o.	PROPN
cusj-5637	151	7	suzuki	suzuki	PROPN
cusj-5637	151	8	,	,	PUNCT
cusj-5637	151	9	m.	m.	NOUN
cusj-5637	151	10	weiker	weiker	PROPN
cusj-5637	151	11	,	,	PUNCT
cusj-5637	151	12	j.	j.	PROPN
cusj-5637	151	13	e.	e.	PROPN
cusj-5637	151	14	goldman	goldman	PROPN
cusj-5637	151	15	,	,	PUNCT
cusj-5637	151	16	j.	j.	PROPN
cusj-5637	151	17	n.	n.	PROPN
cusj-5637	151	18	bruce	bruce	PROPN
cusj-5637	151	19	,	,	PUNCT
cusj-5637	151	20	and	and	CCONJ
cusj-5637	151	21	p.	p.	PROPN
cusj-5637	151	22	canoll	canoll	NOUN
cusj-5637	151	23	.	.	PUNCT
cusj-5637	152	1	"	"	PUNCT
cusj-5637	152	2	transplanted	transplanted	ADJ
cusj-5637	152	3	glioma	glioma	NOUN
cusj-5637	152	4	cells	cell	NOUN
cusj-5637	152	5	migrate	migrate	VERB
cusj-5637	152	6	and	and	CCONJ
cusj-5637	152	7	proliferate	proliferate	VERB
cusj-5637	152	8	on	on	ADP
cusj-5637	152	9	host	host	NOUN
cusj-5637	152	10	brain	brain	NOUN
cusj-5637	152	11	vasculature	vasculature	NOUN
cusj-5637	152	12	:	:	PUNCT
cusj-5637	152	13	a	a	DET
cusj-5637	152	14	dynamic	dynamic	ADJ
cusj-5637	152	15	analysis	analysis	NOUN
cusj-5637	152	16	.	.	PUNCT
cusj-5637	152	17	"	"	PUNCT
cusj-5637	153	1	glia	glia	NOUN
cusj-5637	153	2	53	53	NUM
cusj-5637	153	3	,	,	PUNCT
cusj-5637	153	4	no	no	INTJ
cusj-5637	153	5	.	.	NOUN
cusj-5637	153	6	8	8	NUM
cusj-5637	153	7	(	(	PUNCT
cusj-5637	153	8	jun	jun	PROPN
cusj-5637	153	9	2006	2006	NUM
cusj-5637	153	10	):	):	PUNCT
cusj-5637	153	11	799	799	NUM
cusj-5637	153	12	-	-	SYM
cusj-5637	153	13	808	808	NUM
cusj-5637	153	14	.	.	NOUN
cusj-5637	153	15	5	5	NUM
cusj-5637	153	16	.	.	X
cusj-5637	153	17	fukata	fukata	PROPN
cusj-5637	153	18	,	,	PUNCT
cusj-5637	153	19	y.	y.	PROPN
cusj-5637	153	20	,	,	PUNCT
cusj-5637	153	21	m.	m.	NOUN
cusj-5637	153	22	amano	amano	PROPN
cusj-5637	153	23	,	,	PUNCT
cusj-5637	153	24	and	and	CCONJ
cusj-5637	153	25	k.	k.	PROPN
cusj-5637	153	26	kaibuchi	kaibuchi	PROPN
cusj-5637	153	27	.	.	PUNCT
cusj-5637	154	1	"	"	PUNCT
cusj-5637	154	2	rho	rho	ADJ
cusj-5637	154	3	-	-	ADJ
cusj-5637	154	4	rho	rho	ADJ
cusj-5637	154	5	-	-	PUNCT
cusj-5637	154	6	kinase	kinase	NOUN
cusj-5637	154	7	pathway	pathway	NOUN
cusj-5637	154	8	in	in	ADP
cusj-5637	154	9	smooth	smooth	ADJ
cusj-5637	154	10	muscle	muscle	NOUN
cusj-5637	154	11	contraction	contraction	NOUN
cusj-5637	154	12	and	and	CCONJ
cusj-5637	154	13	cytoskeletal	cytoskeletal	ADJ
cusj-5637	154	14	reorganization	reorganization	NOUN
cusj-5637	154	15	of	of	ADP
cusj-5637	154	16	non	non	ADJ
cusj-5637	154	17	-	-	ADJ
cusj-5637	154	18	muscle	muscle	ADJ
cusj-5637	154	19	cells	cell	NOUN
cusj-5637	154	20	.	.	PUNCT
cusj-5637	154	21	"	"	PUNCT
cusj-5637	155	1	trends	trend	NOUN
cusj-5637	155	2	pharmacol	pharmacol	VERB
cusj-5637	155	3	sci	sci	PROPN
cusj-5637	155	4	22	22	NUM
cusj-5637	155	5	,	,	PUNCT
cusj-5637	155	6	no	no	INTJ
cusj-5637	155	7	.	.	NOUN
cusj-5637	155	8	1	1	NUM
cusj-5637	155	9	(	(	PUNCT
cusj-5637	155	10	jan	jan	PROPN
cusj-5637	155	11	2001	2001	NUM
cusj-5637	155	12	):	):	PUNCT
cusj-5637	155	13	32	32	NUM
cusj-5637	155	14	-	-	SYM
cusj-5637	155	15	9	9	NUM
cusj-5637	155	16	.	.	NOUN
cusj-5637	155	17	6	6	NUM
cusj-5637	155	18	.	.	X
cusj-5637	156	1	giese	giese	PROPN
cusj-5637	156	2	,	,	PUNCT
cusj-5637	156	3	a.	a.	NOUN
cusj-5637	156	4	"	"	PUNCT
cusj-5637	156	5	glioma	glioma	NOUN
cusj-5637	156	6	invasion	invasion	NOUN
cusj-5637	156	7	--	--	PUNCT
cusj-5637	156	8	pattern	pattern	NOUN
cusj-5637	156	9	of	of	ADP
cusj-5637	156	10	dissemination	dissemination	NOUN
cusj-5637	156	11	by	by	ADP
cusj-5637	156	12	mechanisms	mechanism	NOUN
cusj-5637	156	13	of	of	ADP
cusj-5637	156	14	invasion	invasion	NOUN
cusj-5637	156	15	and	and	CCONJ
cusj-5637	156	16	surgical	surgical	ADJ
cusj-5637	156	17	intervention	intervention	NOUN
cusj-5637	156	18	,	,	PUNCT
cusj-5637	156	19	pattern	pattern	NOUN
cusj-5637	156	20	of	of	ADP
cusj-5637	156	21	gene	gene	NOUN
cusj-5637	156	22	expression	expression	NOUN
cusj-5637	156	23	and	and	CCONJ
cusj-5637	156	24	its	its	PRON
cusj-5637	156	25	regulatory	regulatory	ADJ
cusj-5637	156	26	control	control	NOUN
cusj-5637	156	27	by	by	ADP
cusj-5637	156	28	tumor	tumor	NOUN
cusj-5637	156	29	suppressor	suppressor	NOUN
cusj-5637	156	30	p53	p53	NOUN
cusj-5637	156	31	and	and	CCONJ
cusj-5637	156	32	proto	proto	NOUN
cusj-5637	156	33	-	-	PUNCT
cusj-5637	156	34	oncogene	oncogene	NOUN
cusj-5637	156	35	ets-1	ets-1	NOUN
cusj-5637	156	36	.	.	PUNCT
cusj-5637	156	37	"	"	PUNCT
cusj-5637	157	1	acta	acta	PROPN
cusj-5637	157	2	neurochir	neurochir	PROPN
cusj-5637	157	3	suppl	suppl	PROPN
cusj-5637	157	4	88	88	NUM
cusj-5637	157	5	(	(	PUNCT
cusj-5637	157	6	2003	2003	NUM
cusj-5637	157	7	):	):	PUNCT
cusj-5637	157	8	153	153	NUM
cusj-5637	157	9	-	-	SYM
cusj-5637	157	10	62	62	NUM
cusj-5637	157	11	.	.	PUNCT
cusj-5637	158	1	7	7	X
cusj-5637	158	2	.	.	X
cusj-5637	158	3	gillespie	gillespie	PROPN
cusj-5637	158	4	,	,	PUNCT
cusj-5637	158	5	g.	g.	PROPN
cusj-5637	158	6	y.	y.	PROPN
cusj-5637	158	7	,	,	PUNCT
cusj-5637	158	8	l.	l.	PROPN
cusj-5637	158	9	soroceanu	soroceanu	PROPN
cusj-5637	158	10	,	,	PUNCT
cusj-5637	158	11	t.	t.	PROPN
cusj-5637	158	12	j.	j.	PROPN
cusj-5637	158	13	manning	manning	PROPN
cusj-5637	158	14	,	,	PUNCT
cusj-5637	158	15	jr	jr	PROPN
cusj-5637	158	16	.	.	PROPN
cusj-5637	158	17	,	,	PUNCT
cusj-5637	158	18	c.	c.	PROPN
cusj-5637	158	19	l.	l.	PROPN
cusj-5637	158	20	gladson	gladson	PROPN
cusj-5637	158	21	,	,	PUNCT
cusj-5637	158	22	and	and	CCONJ
cusj-5637	158	23	s.	s.	PROPN
cusj-5637	158	24	s.	s.	PROPN
cusj-5637	158	25	rosenfeld	rosenfeld	PROPN
cusj-5637	158	26	.	.	PUNCT
cusj-5637	159	1	"	"	PUNCT
cusj-5637	159	2	glioma	glioma	NOUN
cusj-5637	159	3	migration	migration	NOUN
cusj-5637	159	4	can	can	AUX
cusj-5637	159	5	be	be	AUX
cusj-5637	159	6	blocked	block	VERB
cusj-5637	159	7	by	by	ADP
cusj-5637	159	8	nontoxic	nontoxic	ADJ
cusj-5637	159	9	inhibitors	inhibitor	NOUN
cusj-5637	159	10	of	of	ADP
cusj-5637	159	11	myosin	myosin	PROPN
cusj-5637	159	12	ii	ii	PROPN
cusj-5637	159	13	.	.	PUNCT
cusj-5637	159	14	"	"	PUNCT
cusj-5637	160	1	cancer	cancer	NOUN
cusj-5637	160	2	res	re	NOUN
cusj-5637	160	3	59	59	NUM
cusj-5637	160	4	,	,	PUNCT
cusj-5637	160	5	no	no	INTJ
cusj-5637	160	6	.	.	NOUN
cusj-5637	160	7	9	9	NUM
cusj-5637	160	8	(	(	PUNCT
cusj-5637	160	9	may	may	PROPN
cusj-5637	160	10	1	1	NUM
cusj-5637	160	11	1999	1999	NUM
cusj-5637	160	12	):	):	PUNCT
cusj-5637	160	13	2076	2076	NUM
cusj-5637	160	14	-	-	SYM
cusj-5637	160	15	82	82	NUM
cusj-5637	160	16	.	.	NOUN
cusj-5637	160	17	8	8	NUM
cusj-5637	160	18	.	.	X
cusj-5637	160	19	heissler	heissler	NOUN
cusj-5637	160	20	,	,	PUNCT
cusj-5637	160	21	s.	s.	PROPN
cusj-5637	160	22	m.	m.	PROPN
cusj-5637	160	23	,	,	PUNCT
cusj-5637	160	24	x.	x.	PROPN
cusj-5637	160	25	liu	liu	PROPN
cusj-5637	160	26	,	,	PUNCT
cusj-5637	160	27	e.	e.	PROPN
cusj-5637	160	28	d.	d.	PROPN
cusj-5637	160	29	korn	korn	PROPN
cusj-5637	160	30	,	,	PUNCT
cusj-5637	160	31	and	and	CCONJ
cusj-5637	160	32	j.	j.	PROPN
cusj-5637	160	33	r.	r.	PROPN
cusj-5637	160	34	sellers	sellers	PROPN
cusj-5637	160	35	.	.	PUNCT
cusj-5637	161	1	"	"	PUNCT
cusj-5637	161	2	kinetic	kinetic	ADJ
cusj-5637	161	3	characterization	characterization	NOUN
cusj-5637	161	4	of	of	ADP
cusj-5637	161	5	the	the	DET
cusj-5637	161	6	atpase	atpase	PROPN
cusj-5637	161	7	and	and	CCONJ
cusj-5637	161	8	actin	actin	NOUN
cusj-5637	161	9	-	-	PUNCT
cusj-5637	161	10	activated	activate	VERB
cusj-5637	161	11	atpase	atpase	NOUN
cusj-5637	161	12	activities	activity	NOUN
cusj-5637	161	13	of	of	ADP
cusj-5637	161	14	acanthamoeba	acanthamoeba	PROPN
cusj-5637	161	15	castellanii	castellanii	VERB
cusj-5637	161	16	myosin-2	myosin-2	NOUN
cusj-5637	161	17	.	.	PUNCT
cusj-5637	161	18	"	"	PUNCT
cusj-5637	162	1	j	j	PROPN
cusj-5637	162	2	biol	biol	PROPN
cusj-5637	162	3	chem	chem	NOUN
cusj-5637	162	4	288	288	NUM
cusj-5637	162	5	,	,	PUNCT
cusj-5637	162	6	no	no	INTJ
cusj-5637	162	7	.	.	NOUN
cusj-5637	162	8	37	37	NUM
cusj-5637	162	9	(	(	PUNCT
cusj-5637	162	10	sep	sep	PROPN
cusj-5637	162	11	13	13	NUM
cusj-5637	162	12	2013	2013	NUM
cusj-5637	162	13	):	):	PUNCT
cusj-5637	162	14	26709	26709	NUM
cusj-5637	162	15	-	-	SYM
cusj-5637	162	16	20	20	NUM
cusj-5637	162	17	.	.	NOUN
cusj-5637	162	18	9	9	NUM
cusj-5637	162	19	.	.	X
cusj-5637	163	1	kamm	kamm	PROPN
cusj-5637	163	2	,	,	PUNCT
cusj-5637	163	3	k.	k.	PROPN
cusj-5637	163	4	e.	e.	PROPN
cusj-5637	163	5	,	,	PUNCT
cusj-5637	163	6	l.	l.	PROPN
cusj-5637	163	7	c.	c.	PROPN
cusj-5637	163	8	hsu	hsu	PROPN
cusj-5637	163	9	,	,	PUNCT
cusj-5637	163	10	y.	y.	PROPN
cusj-5637	163	11	kubota	kubota	PROPN
cusj-5637	163	12	,	,	PUNCT
cusj-5637	163	13	and	and	CCONJ
cusj-5637	163	14	j.	j.	PROPN
cusj-5637	163	15	t.	t.	PROPN
cusj-5637	163	16	stull	stull	PROPN
cusj-5637	163	17	.	.	PUNCT
cusj-5637	164	1	"	"	PUNCT
cusj-5637	164	2	phosphorylation	phosphorylation	NOUN
cusj-5637	164	3	of	of	ADP
cusj-5637	164	4	smooth	smooth	ADJ
cusj-5637	164	5	muscle	muscle	NOUN
cusj-5637	164	6	myosin	myosin	PROPN
cusj-5637	164	7	heavy	heavy	ADJ
cusj-5637	164	8	and	and	CCONJ
cusj-5637	164	9	light	light	ADJ
cusj-5637	164	10	chains	chain	NOUN
cusj-5637	164	11	.	.	PUNCT
cusj-5637	165	1	effects	effect	NOUN
cusj-5637	165	2	of	of	ADP
cusj-5637	165	3	phorbol	phorbol	NOUN
cusj-5637	165	4	dibutyrate	dibutyrate	NOUN
cusj-5637	165	5	and	and	CCONJ
cusj-5637	165	6	agonists	agonist	NOUN
cusj-5637	165	7	.	.	PUNCT
cusj-5637	165	8	"	"	PUNCT
cusj-5637	166	1	j	j	PROPN
cusj-5637	166	2	biol	biol	PROPN
cusj-5637	166	3	chem	chem	NOUN
cusj-5637	166	4	264	264	NUM
cusj-5637	166	5	,	,	PUNCT
cusj-5637	166	6	no	no	INTJ
cusj-5637	166	7	.	.	NOUN
cusj-5637	166	8	35	35	NUM
cusj-5637	166	9	(	(	PUNCT
cusj-5637	166	10	dec	dec	PROPN
cusj-5637	166	11	15	15	NUM
cusj-5637	166	12	1989	1989	NUM
cusj-5637	166	13	):	):	PUNCT
cusj-5637	166	14	21223	21223	NUM
cusj-5637	166	15	-	-	SYM
cusj-5637	166	16	9	9	NUM
cusj-5637	166	17	.	.	NOUN
cusj-5637	166	18	10	10	NUM
cusj-5637	166	19	.	.	X
cusj-5637	166	20	sonabend	sonabend	NOUN
cusj-5637	166	21	,	,	PUNCT
cusj-5637	166	22	a.	a.	NOUN
cusj-5637	166	23	m.	m.	NOUN
cusj-5637	166	24	,	,	PUNCT
cusj-5637	166	25	j.	j.	PROPN
cusj-5637	166	26	yun	yun	PROPN
cusj-5637	166	27	,	,	PUNCT
cusj-5637	166	28	l.	l.	PROPN
cusj-5637	166	29	lei	lei	PROPN
cusj-5637	166	30	,	,	PUNCT
cusj-5637	166	31	r.	r.	PROPN
cusj-5637	166	32	leung	leung	PROPN
cusj-5637	166	33	,	,	PUNCT
cusj-5637	166	34	c.	c.	PROPN
cusj-5637	166	35	soderquist	soderquist	PROPN
cusj-5637	166	36	,	,	PUNCT
cusj-5637	166	37	c.	c.	PROPN
cusj-5637	166	38	crisman	crisman	PROPN
cusj-5637	166	39	,	,	PUNCT
cusj-5637	166	40	b.	b.	PROPN
cusj-5637	166	41	j.	j.	PROPN
cusj-5637	166	42	gill	gill	PROPN
cusj-5637	166	43	,	,	PUNCT
cusj-5637	166	44	et	et	PROPN
cusj-5637	166	45	al	al	PROPN
cusj-5637	166	46	.	.	PUNCT
cusj-5637	167	1	"	"	PUNCT
cusj-5637	167	2	murine	murine	ADJ
cusj-5637	167	3	cell	cell	NOUN
cusj-5637	167	4	line	line	NOUN
cusj-5637	167	5	model	model	NOUN
cusj-5637	167	6	of	of	ADP
cusj-5637	167	7	proneural	proneural	ADJ
cusj-5637	167	8	glioma	glioma	NOUN
cusj-5637	167	9	for	for	ADP
cusj-5637	167	10	evaluation	evaluation	NOUN
cusj-5637	167	11	of	of	ADP
cusj-5637	167	12	anti	anti	ADJ
cusj-5637	167	13	-	-	ADJ
cusj-5637	167	14	tumor	tumor	ADJ
cusj-5637	167	15	therapies	therapy	NOUN
cusj-5637	167	16	.	.	PUNCT
cusj-5637	167	17	"	"	PUNCT
cusj-5637	168	1	j	j	PROPN
cusj-5637	168	2	neurooncol	neurooncol	PROPN
cusj-5637	168	3	112	112	NUM
cusj-5637	168	4	,	,	PUNCT
cusj-5637	168	5	no	no	INTJ
cusj-5637	168	6	.	.	NOUN
cusj-5637	168	7	3	3	NUM
cusj-5637	168	8	(	(	PUNCT
cusj-5637	168	9	may	may	PROPN
cusj-5637	168	10	2013	2013	NUM
cusj-5637	168	11	):	):	PUNCT
cusj-5637	168	12	375	375	NUM
cusj-5637	168	13	-	-	SYM
cusj-5637	168	14	82	82	NUM
cusj-5637	168	15	.	.	PUNCT
cusj-5637	168	16	11	11	NUM
cusj-5637	168	17	.	.	X
cusj-5637	169	1	tan	tan	PROPN
cusj-5637	169	2	,	,	PUNCT
cusj-5637	169	3	j.	j.	PROPN
cusj-5637	169	4	l.	l.	PROPN
cusj-5637	169	5	,	,	PUNCT
cusj-5637	169	6	s.	s.	PROPN
cusj-5637	169	7	ravid	ravid	PROPN
cusj-5637	169	8	,	,	PUNCT
cusj-5637	169	9	and	and	CCONJ
cusj-5637	169	10	j.	j.	PROPN
cusj-5637	169	11	a.	a.	PROPN
cusj-5637	169	12	spudich	spudich	PROPN
cusj-5637	169	13	.	.	PUNCT
cusj-5637	170	1	"	"	PUNCT
cusj-5637	170	2	control	control	NOUN
cusj-5637	170	3	of	of	ADP
cusj-5637	170	4	nonmuscle	nonmuscle	PROPN
cusj-5637	170	5	myosins	myosin	NOUN
cusj-5637	170	6	by	by	ADP
cusj-5637	170	7	phosphorylation	phosphorylation	NOUN
cusj-5637	170	8	.	.	PUNCT
cusj-5637	170	9	"	"	PUNCT
cusj-5637	171	1	annu	annu	PROPN
cusj-5637	171	2	rev	rev	VERB
cusj-5637	171	3	biochem	biochem	PROPN
cusj-5637	171	4	61	61	NUM
cusj-5637	171	5	(	(	PUNCT
cusj-5637	171	6	1992	1992	NUM
cusj-5637	171	7	):	):	PUNCT
cusj-5637	171	8	721	721	NUM
cusj-5637	171	9	-	-	SYM
cusj-5637	171	10	59	59	NUM
cusj-5637	171	11	.	.	PUNCT
cusj-5637	171	12	12	12	NUM
cusj-5637	171	13	.	.	PUNCT
cusj-5637	172	1	van	van	PROPN
cusj-5637	172	2	meerloo	meerloo	PROPN
cusj-5637	172	3	,	,	PUNCT
cusj-5637	172	4	j.	j.	PROPN
cusj-5637	172	5	,	,	PUNCT
cusj-5637	172	6	g.	g.	PROPN
cusj-5637	172	7	j.	j.	PROPN
cusj-5637	172	8	kaspers	kaspers	PROPN
cusj-5637	172	9	,	,	PUNCT
cusj-5637	172	10	and	and	CCONJ
cusj-5637	172	11	j.	j.	PROPN
cusj-5637	172	12	cloos	cloos	PROPN
cusj-5637	172	13	.	.	PUNCT
cusj-5637	173	1	"	"	PUNCT
cusj-5637	173	2	cell	cell	NOUN
cusj-5637	173	3	sensitivity	sensitivity	NOUN
cusj-5637	173	4	assays	assay	NOUN
cusj-5637	173	5	:	:	PUNCT
cusj-5637	173	6	the	the	DET
cusj-5637	173	7	mtt	mtt	NOUN
cusj-5637	173	8	assay	assay	VERB
cusj-5637	173	9	.	.	PUNCT
cusj-5637	173	10	"	"	PUNCT
cusj-5637	174	1	methods	method	NOUN
cusj-5637	174	2	mol	mol	ADP
cusj-5637	174	3	biol	biol	PROPN
cusj-5637	174	4	731	731	NUM
cusj-5637	174	5	(	(	PUNCT
cusj-5637	174	6	2011	2011	NUM
cusj-5637	174	7	):	):	PUNCT
cusj-5637	174	8	237	237	NUM
cusj-5637	174	9	-	-	SYM
cusj-5637	174	10	45	45	NUM
cusj-5637	174	11	.	.	NOUN
cusj-5637	174	12	13	13	NUM
cusj-5637	174	13	.	.	PUNCT
cusj-5637	175	1	vicente	vicente	NOUN
cusj-5637	175	2	-	-	PUNCT
cusj-5637	175	3	manzanares	manzanare	NOUN
cusj-5637	175	4	,	,	PUNCT
cusj-5637	175	5	m.	m.	NOUN
cusj-5637	175	6	,	,	PUNCT
cusj-5637	175	7	x.	x.	PROPN
cusj-5637	175	8	ma	ma	PROPN
cusj-5637	175	9	,	,	PUNCT
cusj-5637	175	10	r.	r.	PROPN
cusj-5637	175	11	s.	s.	PROPN
cusj-5637	175	12	adelstein	adelstein	PROPN
cusj-5637	175	13	,	,	PUNCT
cusj-5637	175	14	and	and	CCONJ
cusj-5637	175	15	a.	a.	PROPN
cusj-5637	175	16	r.	r.	PROPN
cusj-5637	175	17	horwitz	horwitz	PROPN
cusj-5637	175	18	.	.	PUNCT
cusj-5637	176	1	"	"	PUNCT
cusj-5637	176	2	non	non	ADJ
cusj-5637	176	3	-	-	ADJ
cusj-5637	176	4	muscle	muscle	ADJ
cusj-5637	176	5	myosin	myosin	PROPN
cusj-5637	176	6	ii	ii	PROPN
cusj-5637	176	7	takes	take	VERB
cusj-5637	176	8	centre	centre	NOUN
cusj-5637	176	9	stage	stage	NOUN
cusj-5637	176	10	in	in	ADP
cusj-5637	176	11	cell	cell	NOUN
cusj-5637	176	12	adhesion	adhesion	NOUN
cusj-5637	176	13	and	and	CCONJ
cusj-5637	176	14	migration	migration	NOUN
cusj-5637	176	15	.	.	PUNCT
cusj-5637	176	16	"	"	PUNCT
cusj-5637	177	1	nat	nat	PROPN
cusj-5637	177	2	rev	rev	VERB
cusj-5637	177	3	mol	mol	ADP
cusj-5637	177	4	cell	cell	NOUN
cusj-5637	177	5	biol	biol	NOUN
cusj-5637	177	6	10	10	NUM
cusj-5637	177	7	,	,	PUNCT
cusj-5637	177	8	no	no	INTJ
cusj-5637	177	9	.	.	NOUN
cusj-5637	177	10	11	11	NUM
cusj-5637	177	11	(	(	PUNCT
cusj-5637	177	12	nov	nov	PROPN
cusj-5637	177	13	2009	2009	NUM
cusj-5637	177	14	):	):	PUNCT
cusj-5637	177	15	778	778	NUM
cusj-5637	177	16	-	-	SYM
cusj-5637	177	17	90	90	NUM
cusj-5637	177	18	.	.	PUNCT
cusj-5637	177	19	biology	biology	NOUN