id	sid	tid	token	lemma	pos
cusj-5649	1	1	columbia	columbia	PROPN
cusj-5649	1	2	undergraduate	undergraduate	PROPN
cusj-5649	1	3	science	science	PROPN
cusj-5649	1	4	journal	journal	PROPN
cusj-5649	1	5	open	open	ADJ
cusj-5649	1	6	-	-	PUNCT
cusj-5649	1	7	access	access	NOUN
cusj-5649	1	8	publication	publication	NOUN
cusj-5649	1	9	|	|	ADV
cusj-5649	1	10	http://cusj.columbia.com	http://cusj.columbia.com	X
cusj-5649	1	11	42	42	NUM
cusj-5649	1	12	cusjvolume	cusjvolume	ADJ
cusj-5649	1	13	5spring	5spring	NUM
cusj-5649	1	14	2011	2011	NUM
cusj-5649	1	15	columbia	columbia	PROPN
cusj-5649	1	16	undergraduate	undergraduate	NOUN
cusj-5649	1	17	sci	sci	PROPN
cusj-5649	1	18	j	j	PROPN
cusj-5649	1	19	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	1	20	v	v	ADP
cusj-5649	1	21	ir	ir	PROPN
cusj-5649	1	22	o	o	NOUN
cusj-5649	2	1	lo	lo	NOUN
cusj-5649	2	2	g	g	PROPN
cusj-5649	2	3	y	y	PROPN
cusj-5649	2	4	cusjcolumbia	cusjcolumbia	ADJ
cusj-5649	2	5	undergraduate	undergraduate	NOUN
cusj-5649	2	6	science	science	NOUN
cusj-5649	2	7	journalresearch	journalresearch	NOUN
cusj-5649	2	8	articles	article	NOUN
cusj-5649	2	9	43cusj	43cusj	PRON
cusj-5649	3	1	volume	volume	NOUN
cusj-5649	3	2	5spring	5spring	NUM
cusj-5649	3	3	2011	2011	NUM
cusj-5649	4	1	columbia	columbia	PROPN
cusj-5649	4	2	undergraduate	undergraduate	NOUN
cusj-5649	4	3	sci	sci	PROPN
cusj-5649	4	4	j	j	PROPN
cusj-5649	4	5	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	4	6	v	v	ADP
cusj-5649	4	7	ir	ir	PROPN
cusj-5649	4	8	o	o	NOUN
cusj-5649	5	1	lo	lo	NOUN
cusj-5649	5	2	g	g	PROPN
cusj-5649	5	3	y	y	PROPN
cusj-5649	5	4	overall	overall	ADJ
cusj-5649	5	5	survival	survival	NOUN
cusj-5649	5	6	rates	rate	NOUN
cusj-5649	5	7	.	.	PUNCT
cusj-5649	6	1	preventing	prevent	VERB
cusj-5649	6	2	glioma	glioma	NOUN
cusj-5649	6	3	invasion	invasion	NOUN
cusj-5649	6	4	has	have	VERB
cusj-5649	6	5	the	the	DET
cusj-5649	6	6	potential	potential	NOUN
cusj-5649	6	7	to	to	PART
cusj-5649	6	8	convert	convert	VERB
cusj-5649	6	9	this	this	DET
cusj-5649	6	10	highly	highly	ADV
cusj-5649	6	11	malignant	malignant	ADJ
cusj-5649	6	12	tumor	tumor	NOUN
cusj-5649	6	13	into	into	ADP
cusj-5649	6	14	a	a	DET
cusj-5649	6	15	focal	focal	ADJ
cusj-5649	6	16	disease	disease	NOUN
cusj-5649	6	17	,	,	PUNCT
cusj-5649	6	18	which	which	PRON
cusj-5649	6	19	could	could	AUX
cusj-5649	6	20	then	then	ADV
cusj-5649	6	21	be	be	AUX
cusj-5649	6	22	e!ectively	e!ectively	ADV
cusj-5649	6	23	treated	treat	VERB
cusj-5649	6	24	with	with	ADP
cusj-5649	6	25	focal	focal	ADJ
cusj-5649	6	26	therapies	therapy	NOUN
cusj-5649	6	27	,	,	PUNCT
cusj-5649	6	28	such	such	ADJ
cusj-5649	6	29	as	as	ADP
cusj-5649	6	30	radiation	radiation	NOUN
cusj-5649	6	31	and	and	CCONJ
cusj-5649	6	32	surgery	surgery	NOUN
cusj-5649	6	33	(	(	PUNCT
cusj-5649	6	34	madsen	madsen	PROPN
cusj-5649	6	35	,	,	PUNCT
cusj-5649	6	36	2003	2003	NUM
cusj-5649	6	37	;	;	PUNCT
cusj-5649	6	38	gillespie	gillespie	PROPN
cusj-5649	6	39	,	,	PUNCT
cusj-5649	6	40	1999	1999	NUM
cusj-5649	6	41	)	)	PUNCT
cusj-5649	6	42	.	.	PUNCT
cusj-5649	7	1	invasion	invasion	NOUN
cusj-5649	7	2	and	and	CCONJ
cusj-5649	7	3	migration	migration	NOUN
cusj-5649	7	4	of	of	ADP
cusj-5649	7	5	malignant	malignant	ADJ
cusj-5649	7	6	gliomas	glioma	NOUN
cusj-5649	7	7	tissue	tissue	NOUN
cusj-5649	7	8	invasion	invasion	NOUN
cusj-5649	7	9	by	by	ADP
cusj-5649	7	10	malignant	malignant	ADJ
cusj-5649	7	11	gliomas	glioma	NOUN
cusj-5649	7	12	is	be	AUX
cusj-5649	7	13	a	a	DET
cusj-5649	7	14	multi	multi	ADJ
cusj-5649	7	15	-	-	ADJ
cusj-5649	7	16	step	step	ADJ
cusj-5649	7	17	process	process	NOUN
cusj-5649	7	18	.	.	PUNCT
cusj-5649	8	1	central	central	ADJ
cusj-5649	8	2	to	to	ADP
cusj-5649	8	3	this	this	PRON
cusj-5649	8	4	is	be	AUX
cusj-5649	8	5	the	the	DET
cusj-5649	8	6	ability	ability	NOUN
cusj-5649	8	7	of	of	ADP
cusj-5649	8	8	transformed	transform	VERB
cusj-5649	8	9	cells	cell	NOUN
cusj-5649	8	10	to	to	PART
cusj-5649	8	11	crawl	crawl	VERB
cusj-5649	8	12	through	through	ADP
cusj-5649	8	13	the	the	DET
cusj-5649	8	14	extracellular	extracellular	ADJ
cusj-5649	8	15	matrix	matrix	NOUN
cusj-5649	8	16	.	.	PUNCT
cusj-5649	9	1	"	"	PUNCT
cusj-5649	9	2	e	e	X
cusj-5649	9	3	initial	initial	ADJ
cusj-5649	9	4	step	step	NOUN
cusj-5649	9	5	requires	require	VERB
cusj-5649	9	6	receptor	receptor	NOUN
cusj-5649	9	7	-	-	PUNCT
cusj-5649	9	8	mediated	mediate	VERB
cusj-5649	9	9	adhesion	adhesion	NOUN
cusj-5649	9	10	of	of	ADP
cusj-5649	9	11	tumor	tumor	NOUN
cusj-5649	9	12	cells	cell	NOUN
cusj-5649	9	13	to	to	PART
cusj-5649	9	14	matrix	matrix	VERB
cusj-5649	9	15	proteins	protein	NOUN
cusj-5649	9	16	,	,	PUNCT
cusj-5649	9	17	followed	follow	VERB
cusj-5649	9	18	by	by	ADP
cusj-5649	9	19	a	a	DET
cusj-5649	9	20	second	second	ADJ
cusj-5649	9	21	phase	phase	NOUN
cusj-5649	9	22	of	of	ADP
cusj-5649	9	23	degradation	degradation	NOUN
cusj-5649	9	24	of	of	ADP
cusj-5649	9	25	the	the	DET
cusj-5649	9	26	matrix	matrix	NOUN
cusj-5649	9	27	by	by	ADP
cusj-5649	9	28	tumor	tumor	NOUN
cusj-5649	9	29	-	-	PUNCT
cusj-5649	9	30	secreted	secrete	VERB
cusj-5649	9	31	proteases	protease	NOUN
cusj-5649	9	32	.	.	PUNCT
cusj-5649	10	1	"	"	PUNCT
cusj-5649	10	2	e	e	NOUN
cusj-5649	10	3	ability	ability	NOUN
cusj-5649	10	4	of	of	ADP
cusj-5649	10	5	invasive	invasive	ADJ
cusj-5649	10	6	glioma	glioma	NOUN
cusj-5649	10	7	cells	cell	NOUN
cusj-5649	10	8	to	to	PART
cusj-5649	10	9	navigate	navigate	VERB
cusj-5649	10	10	these	these	DET
cusj-5649	10	11	diverse	diverse	ADJ
cusj-5649	10	12	anatomic	anatomic	ADJ
cusj-5649	10	13	structures	structure	NOUN
cusj-5649	10	14	and	and	CCONJ
cusj-5649	10	15	molecular	molecular	ADJ
cusj-5649	10	16	substrates	substrate	NOUN
cusj-5649	10	17	raises	raise	VERB
cusj-5649	10	18	the	the	DET
cusj-5649	10	19	question	question	NOUN
cusj-5649	10	20	of	of	ADP
cusj-5649	10	21	whether	whether	SCONJ
cusj-5649	10	22	speci#c	speci#c	ADJ
cusj-5649	10	23	mechanisms	mechanism	NOUN
cusj-5649	10	24	and	and	CCONJ
cusj-5649	10	25	phenotypes	phenotype	NOUN
cusj-5649	10	26	of	of	ADP
cusj-5649	10	27	invasive	invasive	ADJ
cusj-5649	10	28	cells	cell	NOUN
cusj-5649	10	29	are	be	AUX
cusj-5649	10	30	involved	involve	VERB
cusj-5649	10	31	in	in	ADP
cusj-5649	10	32	dispersion	dispersion	NOUN
cusj-5649	10	33	following	follow	VERB
cusj-5649	10	34	speci#c	speci#c	ADJ
cusj-5649	10	35	pathways	pathway	NOUN
cusj-5649	10	36	(	(	PUNCT
cusj-5649	10	37	gillespie	gillespie	PROPN
cusj-5649	10	38	,	,	PUNCT
cusj-5649	10	39	1999	1999	NUM
cusj-5649	10	40	)	)	PUNCT
cusj-5649	10	41	.	.	PUNCT
cusj-5649	11	1	gliomas	glioma	NOUN
cusj-5649	11	2	typically	typically	ADV
cusj-5649	11	3	invade	invade	VERB
cusj-5649	11	4	the	the	DET
cusj-5649	11	5	brain	brain	NOUN
cusj-5649	11	6	by	by	ADP
cusj-5649	11	7	migrating	migrate	VERB
cusj-5649	11	8	long	long	ADJ
cusj-5649	11	9	distances	distance	NOUN
cusj-5649	11	10	through	through	ADP
cusj-5649	11	11	white	white	ADJ
cusj-5649	11	12	matter	matter	NOUN
cusj-5649	11	13	tracts	tract	NOUN
cusj-5649	11	14	and	and	CCONJ
cusj-5649	11	15	by	by	ADP
cusj-5649	11	16	in#ltrating	in#ltrate	VERB
cusj-5649	11	17	cortex	cortex	NOUN
cusj-5649	11	18	and	and	CCONJ
cusj-5649	11	19	subcortical	subcortical	ADJ
cusj-5649	11	20	gray	gray	ADJ
cusj-5649	11	21	matter	matter	NOUN
cusj-5649	11	22	structures	structure	NOUN
cusj-5649	11	23	.	.	PUNCT
cusj-5649	12	1	when	when	SCONJ
cusj-5649	12	2	migrating	migrate	VERB
cusj-5649	12	3	through	through	ADP
cusj-5649	12	4	brain	brain	NOUN
cusj-5649	12	5	white	white	PROPN
cusj-5649	12	6	matter	matter	NOUN
cusj-5649	12	7	,	,	PUNCT
cusj-5649	12	8	gliomas	glioma	NOUN
cusj-5649	12	9	move	move	VERB
cusj-5649	12	10	in	in	ADP
cusj-5649	12	11	a	a	DET
cusj-5649	12	12	manner	manner	NOUN
cusj-5649	12	13	remarkably	remarkably	ADV
cusj-5649	12	14	similar	similar	ADJ
cusj-5649	12	15	to	to	ADP
cusj-5649	12	16	that	that	PRON
cusj-5649	12	17	previously	previously	ADV
cusj-5649	12	18	described	describe	VERB
cusj-5649	12	19	for	for	ADP
cusj-5649	12	20	neural	neural	ADJ
cusj-5649	12	21	progenitor	progenitor	NOUN
cusj-5649	12	22	cells	cell	NOUN
cusj-5649	12	23	.	.	PUNCT
cusj-5649	13	1	given	give	VERB
cusj-5649	13	2	the	the	DET
cusj-5649	13	3	submicrometer	submicrometer	ADJ
cusj-5649	13	4	size	size	NOUN
cusj-5649	13	5	of	of	ADP
cusj-5649	13	6	the	the	DET
cusj-5649	13	7	extracellular	extracellular	ADJ
cusj-5649	13	8	spaces	space	NOUN
cusj-5649	13	9	that	that	PRON
cusj-5649	13	10	are	be	AUX
cusj-5649	13	11	present	present	ADJ
cusj-5649	13	12	in	in	ADP
cusj-5649	13	13	the	the	DET
cusj-5649	13	14	tightly	tightly	ADV
cusj-5649	13	15	packed	pack	VERB
cusj-5649	13	16	neuropil	neuropil	NOUN
cusj-5649	13	17	of	of	ADP
cusj-5649	13	18	the	the	DET
cusj-5649	13	19	brain	brain	NOUN
cusj-5649	13	20	,	,	PUNCT
cusj-5649	13	21	most	most	ADJ
cusj-5649	13	22	other	other	ADJ
cusj-5649	13	23	motile	motile	ADJ
cusj-5649	13	24	cells	cell	NOUN
cusj-5649	13	25	would	would	AUX
cusj-5649	13	26	likely	likely	ADV
cusj-5649	13	27	#	#	SYM
cusj-5649	13	28	nd	nd	PRON
cusj-5649	13	29	it	it	PRON
cusj-5649	13	30	impossible	impossible	ADJ
cusj-5649	13	31	to	to	PART
cusj-5649	13	32	migrate	migrate	VERB
cusj-5649	13	33	because	because	SCONJ
cusj-5649	13	34	there	there	PRON
cusj-5649	13	35	would	would	AUX
cusj-5649	13	36	be	be	AUX
cusj-5649	13	37	no	no	DET
cusj-5649	13	38	room	room	NOUN
cusj-5649	13	39	to	to	PART
cusj-5649	13	40	allow	allow	VERB
cusj-5649	13	41	a	a	DET
cusj-5649	13	42	lamellipodium	lamellipodium	NOUN
cusj-5649	13	43	to	to	PART
cusj-5649	13	44	form	form	VERB
cusj-5649	13	45	.	.	PUNCT
cusj-5649	14	1	"	"	PUNCT
cusj-5649	14	2	e	e	X
cusj-5649	14	3	unique	unique	ADJ
cusj-5649	14	4	form	form	NOUN
cusj-5649	14	5	of	of	ADP
cusj-5649	14	6	motility	motility	NOUN
cusj-5649	14	7	shared	share	VERB
cusj-5649	14	8	by	by	ADP
cusj-5649	14	9	gliomas	glioma	NOUN
cusj-5649	14	10	and	and	CCONJ
cusj-5649	14	11	neural	neural	ADJ
cusj-5649	14	12	progenitors	progenitor	NOUN
cusj-5649	14	13	re$ects	re$ect	VERB
cusj-5649	14	14	adaptations	adaptation	NOUN
cusj-5649	14	15	that	that	SCONJ
cusj-5649	14	16	these	these	DET
cusj-5649	14	17	cells	cell	NOUN
cusj-5649	14	18	have	have	VERB
cusj-5649	14	19	to	to	PART
cusj-5649	14	20	make	make	VERB
cusj-5649	14	21	to	to	ADP
cusj-5649	14	22	a	a	DET
cusj-5649	14	23	uniquely	uniquely	ADV
cusj-5649	14	24	challenging	challenging	ADJ
cusj-5649	14	25	environment	environment	NOUN
cusj-5649	14	26	with	with	ADP
cusj-5649	14	27	small	small	ADJ
cusj-5649	14	28	e!ective	e!ective	X
cusj-5649	14	29	pore	pore	ADJ
cusj-5649	14	30	sizes	size	NOUN
cusj-5649	14	31	(	(	PUNCT
cusj-5649	14	32	beadle	beadle	PROPN
cusj-5649	14	33	,	,	PUNCT
cusj-5649	14	34	2008	2008	NUM
cusj-5649	14	35	)	)	PUNCT
cusj-5649	14	36	.	.	PUNCT
cusj-5649	15	1	one	one	NUM
cusj-5649	15	2	of	of	ADP
cusj-5649	15	3	these	these	DET
cusj-5649	15	4	adaptations	adaptation	NOUN
cusj-5649	15	5	is	be	AUX
cusj-5649	15	6	in	in	ADP
cusj-5649	15	7	how	how	SCONJ
cusj-5649	15	8	glioma	glioma	NOUN
cusj-5649	15	9	cells	cell	NOUN
cusj-5649	15	10	use	use	VERB
cusj-5649	15	11	myosin	myosin	PROPN
cusj-5649	15	12	ii	ii	PROPN
cusj-5649	15	13	,	,	PUNCT
cusj-5649	15	14	the	the	DET
cusj-5649	15	15	major	major	ADJ
cusj-5649	15	16	source	source	NOUN
cusj-5649	15	17	of	of	ADP
cusj-5649	15	18	cytoplasmic	cytoplasmic	ADJ
cusj-5649	15	19	contractile	contractile	NOUN
cusj-5649	15	20	force	force	NOUN
cusj-5649	15	21	(	(	PUNCT
cusj-5649	15	22	gillespie	gillespie	PROPN
cusj-5649	15	23	,	,	PUNCT
cusj-5649	15	24	1999	1999	NUM
cusj-5649	15	25	)	)	PUNCT
cusj-5649	15	26	.	.	PUNCT
cusj-5649	16	1	myosin	myosin	PROPN
cusj-5649	16	2	ii	ii	PROPN
cusj-5649	16	3	is	be	AUX
cusj-5649	16	4	absolutely	absolutely	ADV
cusj-5649	16	5	required	require	VERB
cusj-5649	16	6	for	for	ADP
cusj-5649	16	7	migration	migration	NOUN
cusj-5649	16	8	in	in	ADP
cusj-5649	16	9	the	the	DET
cusj-5649	16	10	brain	brain	NOUN
cusj-5649	16	11	,	,	PUNCT
cusj-5649	16	12	where	where	SCONJ
cusj-5649	16	13	its	its	PRON
cusj-5649	16	14	major	major	ADJ
cusj-5649	16	15	role	role	NOUN
cusj-5649	16	16	is	be	AUX
cusj-5649	16	17	to	to	PART
cusj-5649	16	18	push	push	VERB
cusj-5649	16	19	the	the	DET
cusj-5649	16	20	bulky	bulky	ADJ
cusj-5649	16	21	nucleus	nucleus	NOUN
cusj-5649	16	22	and	and	CCONJ
cusj-5649	16	23	cell	cell	NOUN
cusj-5649	16	24	body	body	NOUN
cusj-5649	16	25	through	through	ADP
cusj-5649	16	26	the	the	DET
cusj-5649	16	27	small	small	ADJ
cusj-5649	16	28	pores	pore	NOUN
cusj-5649	16	29	found	find	VERB
cusj-5649	16	30	within	within	ADP
cusj-5649	16	31	the	the	DET
cusj-5649	16	32	brain	brain	NOUN
cusj-5649	16	33	matrix	matrix	NOUN
cusj-5649	16	34	.	.	PUNCT
cusj-5649	17	1	"	"	PUNCT
cusj-5649	17	2	is	be	AUX
cusj-5649	17	3	feature	feature	NOUN
cusj-5649	17	4	distinguishes	distinguish	VERB
cusj-5649	17	5	glial	glial	ADJ
cusj-5649	17	6	cells	cell	NOUN
cusj-5649	17	7	from	from	ADP
cusj-5649	17	8	other	other	ADJ
cusj-5649	17	9	cancers	cancer	NOUN
cusj-5649	17	10	because	because	SCONJ
cusj-5649	17	11	other	other	ADJ
cusj-5649	17	12	cancers	cancer	NOUN
cusj-5649	17	13	do	do	AUX
cusj-5649	17	14	not	not	PART
cusj-5649	17	15	require	require	VERB
cusj-5649	17	16	myosin	myosin	PROPN
cusj-5649	17	17	ii	ii	PROPN
cusj-5649	17	18	for	for	ADP
cusj-5649	17	19	the	the	DET
cusj-5649	17	20	collapse	collapse	NOUN
cusj-5649	17	21	of	of	ADP
cusj-5649	17	22	their	their	PRON
cusj-5649	17	23	nucleus	nucleus	NOUN
cusj-5649	17	24	.	.	PUNCT
cusj-5649	18	1	"	"	PUNCT
cusj-5649	18	2	e	e	X
cusj-5649	18	3	progenitor	progenitor	NOUN
cusj-5649	18	4	-	-	PUNCT
cusj-5649	18	5	like	like	ADJ
cusj-5649	18	6	motility	motility	NOUN
cusj-5649	18	7	of	of	ADP
cusj-5649	18	8	glioma	glioma	NOUN
cusj-5649	18	9	cells	cell	NOUN
cusj-5649	18	10	represents	represent	VERB
cusj-5649	18	11	a	a	DET
cusj-5649	18	12	method	method	NOUN
cusj-5649	18	13	of	of	ADP
cusj-5649	18	14	migration	migration	NOUN
cusj-5649	18	15	that	that	PRON
cusj-5649	18	16	is	be	AUX
cusj-5649	18	17	speci#cally	speci#cally	ADV
cusj-5649	18	18	adapted	adapt	VERB
cusj-5649	18	19	for	for	ADP
cusj-5649	18	20	traversing	traverse	VERB
cusj-5649	18	21	the	the	DET
cusj-5649	18	22	densely	densely	ADV
cusj-5649	18	23	packed	pack	VERB
cusj-5649	18	24	neuropil	neuropil	NOUN
cusj-5649	18	25	of	of	ADP
cusj-5649	18	26	the	the	DET
cusj-5649	18	27	mature	mature	ADJ
cusj-5649	18	28	brain	brain	NOUN
cusj-5649	18	29	(	(	PUNCT
cusj-5649	18	30	beadle	beadle	PROPN
cusj-5649	18	31	,	,	PUNCT
cusj-5649	18	32	2008	2008	NUM
cusj-5649	18	33	)	)	PUNCT
cusj-5649	18	34	.	.	PUNCT
cusj-5649	19	1	poliovirus	poliovirus	NOUN
cusj-5649	19	2	poliovirus	poliovirus	NOUN
cusj-5649	19	3	,	,	PUNCT
cusj-5649	19	4	among	among	ADP
cusj-5649	19	5	other	other	ADJ
cusj-5649	19	6	human	human	ADJ
cusj-5649	19	7	pathogenic	pathogenic	ADJ
cusj-5649	19	8	viruses	virus	NOUN
cusj-5649	19	9	,	,	PUNCT
cusj-5649	19	10	is	be	AUX
cusj-5649	19	11	being	be	AUX
cusj-5649	19	12	studied	study	VERB
cusj-5649	19	13	increasingly	increasingly	ADV
cusj-5649	19	14	along	along	ADP
cusj-5649	19	15	with	with	ADP
cusj-5649	19	16	the	the	DET
cusj-5649	19	17	development	development	NOUN
cusj-5649	19	18	of	of	ADP
cusj-5649	19	19	novel	novel	ADJ
cusj-5649	19	20	therapeutic	therapeutic	ADJ
cusj-5649	19	21	agents	agent	NOUN
cusj-5649	19	22	against	against	ADP
cusj-5649	19	23	malignant	malignant	ADJ
cusj-5649	19	24	glioma	glioma	NOUN
cusj-5649	19	25	.	.	PUNCT
cusj-5649	20	1	poliovirus	poliovirus	NOUN
cusj-5649	20	2	,	,	PUNCT
cusj-5649	20	3	the	the	DET
cusj-5649	20	4	causative	causative	ADJ
cusj-5649	20	5	agent	agent	NOUN
cusj-5649	20	6	of	of	ADP
cusj-5649	20	7	poliomyelitis	poliomyelitis	PROPN
cusj-5649	20	8	,	,	PUNCT
cusj-5649	20	9	is	be	AUX
cusj-5649	20	10	classi#ed	classi#ed	PROPN
cusj-5649	20	11	within	within	ADP
cusj-5649	20	12	the	the	DET
cusj-5649	20	13	enterovirus	enterovirus	NOUN
cusj-5649	20	14	genus	genus	NOUN
cusj-5649	20	15	of	of	ADP
cusj-5649	20	16	the	the	DET
cusj-5649	20	17	family	family	NOUN
cusj-5649	20	18	picornaviridae	picornaviridae	NOUN
cusj-5649	20	19	.	.	PUNCT
cusj-5649	21	1	poliovirus	poliovirus	NOUN
cusj-5649	21	2	is	be	AUX
cusj-5649	21	3	composed	compose	VERB
cusj-5649	21	4	of	of	ADP
cusj-5649	21	5	a	a	DET
cusj-5649	21	6	rna	rna	NOUN
cusj-5649	21	7	genome	genome	NOUN
cusj-5649	21	8	and	and	CCONJ
cusj-5649	21	9	a	a	DET
cusj-5649	21	10	protein	protein	NOUN
cusj-5649	21	11	capsid	capsid	ADJ
cusj-5649	21	12	.	.	PUNCT
cusj-5649	22	1	"	"	PUNCT
cusj-5649	22	2	e	e	X
cusj-5649	22	3	genome	genome	NOUN
cusj-5649	22	4	is	be	AUX
cusj-5649	22	5	single	single	ADJ
cusj-5649	22	6	-	-	PUNCT
cusj-5649	22	7	stranded	strand	VERB
cusj-5649	22	8	positive	positive	ADJ
cusj-5649	22	9	-	-	PUNCT
cusj-5649	22	10	sense	sense	NOUN
cusj-5649	22	11	rna	rna	NOUN
cusj-5649	22	12	genome	genome	NOUN
cusj-5649	22	13	that	that	PRON
cusj-5649	22	14	is	be	AUX
cusj-5649	22	15	about	about	ADV
cusj-5649	22	16	7500	7500	NUM
cusj-5649	22	17	nucleotides	nucleotide	NOUN
cusj-5649	22	18	long	long	ADV
cusj-5649	22	19	,	,	PUNCT
cusj-5649	22	20	while	while	SCONJ
cusj-5649	22	21	the	the	DET
cusj-5649	22	22	viral	viral	ADJ
cusj-5649	22	23	particle	particle	NOUN
cusj-5649	22	24	is	be	AUX
cusj-5649	22	25	about	about	ADV
cusj-5649	22	26	30	30	NUM
cusj-5649	22	27	nanometers	nanometer	NOUN
cusj-5649	22	28	in	in	ADP
cusj-5649	22	29	diameter	diameter	NOUN
cusj-5649	22	30	with	with	ADP
cusj-5649	22	31	icosahedral	icosahedral	ADJ
cusj-5649	22	32	symmetry	symmetry	NOUN
cusj-5649	22	33	.	.	PUNCT
cusj-5649	23	1	because	because	SCONJ
cusj-5649	23	2	of	of	ADP
cusj-5649	23	3	its	its	PRON
cusj-5649	23	4	short	short	ADJ
cusj-5649	23	5	genome	genome	NOUN
cusj-5649	23	6	and	and	CCONJ
cusj-5649	23	7	its	its	PRON
cusj-5649	23	8	simple	simple	ADJ
cusj-5649	23	9	composition	composition	NOUN
cusj-5649	23	10	,	,	PUNCT
cusj-5649	23	11	poliovirus	poliovirus	NOUN
cusj-5649	23	12	is	be	AUX
cusj-5649	23	13	widely	widely	ADV
cusj-5649	23	14	regarded	regard	VERB
cusj-5649	23	15	as	as	ADP
cusj-5649	23	16	the	the	DET
cusj-5649	23	17	simplest	simple	ADJ
cusj-5649	23	18	signi#cant	signi#cant	NOUN
cusj-5649	23	19	virus	virus	NOUN
cusj-5649	23	20	.	.	PUNCT
cusj-5649	24	1	first	first	ADV
cusj-5649	24	2	isolated	isolate	VERB
cusj-5649	24	3	in	in	ADP
cusj-5649	24	4	1909	1909	NUM
cusj-5649	24	5	by	by	ADP
cusj-5649	24	6	karl	karl	PROPN
cusj-5649	24	7	landsteiner	landsteiner	PROPN
cusj-5649	24	8	and	and	CCONJ
cusj-5649	24	9	erwin	erwin	PROPN
cusj-5649	24	10	popper	popper	NOUN
cusj-5649	24	11	,	,	PUNCT
cusj-5649	24	12	poliovirus	poliovirus	NOUN
cusj-5649	24	13	has	have	AUX
cusj-5649	24	14	become	become	VERB
cusj-5649	24	15	one	one	NUM
cusj-5649	24	16	of	of	ADP
cusj-5649	24	17	the	the	DET
cusj-5649	24	18	most	most	ADV
cusj-5649	24	19	well	well	ADV
cusj-5649	24	20	-	-	PUNCT
cusj-5649	24	21	characterized	characterize	VERB
cusj-5649	24	22	viruses	virus	NOUN
cusj-5649	24	23	,	,	PUNCT
cusj-5649	24	24	and	and	CCONJ
cusj-5649	24	25	has	have	AUX
cusj-5649	24	26	become	become	VERB
cusj-5649	24	27	a	a	DET
cusj-5649	24	28	useful	useful	ADJ
cusj-5649	24	29	model	model	NOUN
cusj-5649	24	30	system	system	NOUN
cusj-5649	24	31	for	for	ADP
cusj-5649	24	32	understanding	understand	VERB
cusj-5649	24	33	the	the	DET
cusj-5649	24	34	biology	biology	NOUN
cusj-5649	24	35	of	of	ADP
cusj-5649	24	36	rna	rna	NOUN
cusj-5649	24	37	viruses	virus	NOUN
cusj-5649	24	38	.	.	PUNCT
cusj-5649	25	1	"	"	PUNCT
cusj-5649	25	2	ere	ere	PROPN
cusj-5649	25	3	are	be	AUX
cusj-5649	25	4	three	three	NUM
cusj-5649	25	5	serotypes	serotype	NOUN
cusj-5649	25	6	of	of	ADP
cusj-5649	25	7	poliovirus	poliovirus	NOUN
cusj-5649	25	8	,	,	PUNCT
cusj-5649	25	9	pv1	pv1	NOUN
cusj-5649	25	10	,	,	PUNCT
cusj-5649	25	11	pv2	pv2	NOUN
cusj-5649	25	12	,	,	PUNCT
cusj-5649	25	13	and	and	CCONJ
cusj-5649	25	14	pv3	pv3	NOUN
cusj-5649	25	15	,	,	PUNCT
cusj-5649	25	16	each	each	PRON
cusj-5649	25	17	with	with	ADP
cusj-5649	25	18	a	a	DET
cusj-5649	25	19	slightly	slightly	ADV
cusj-5649	25	20	di!erent	di!erent	NOUN
cusj-5649	25	21	capsid	capsid	NOUN
cusj-5649	25	22	protein	protein	NOUN
cusj-5649	25	23	.	.	PUNCT
cusj-5649	26	1	"	"	PUNCT
cusj-5649	26	2	e	e	X
cusj-5649	26	3	capsid	capsid	ADJ
cusj-5649	26	4	proteins	protein	NOUN
cusj-5649	26	5	de#ne	de#ne	X
cusj-5649	26	6	cellular	cellular	ADJ
cusj-5649	26	7	receptor	receptor	NOUN
cusj-5649	26	8	speci#city	speci#city	NOUN
cusj-5649	26	9	and	and	CCONJ
cusj-5649	26	10	virus	virus	NOUN
cusj-5649	26	11	antigenicity	antigenicity	NOUN
cusj-5649	26	12	.	.	PUNCT
cusj-5649	27	1	pv1	pv1	NOUN
cusj-5649	27	2	is	be	AUX
cusj-5649	27	3	the	the	DET
cusj-5649	27	4	most	most	ADV
cusj-5649	27	5	common	common	ADJ
cusj-5649	27	6	form	form	NOUN
cusj-5649	27	7	encountered	encounter	VERB
cusj-5649	27	8	in	in	ADP
cusj-5649	27	9	nature	nature	NOUN
cusj-5649	27	10	,	,	PUNCT
cusj-5649	27	11	however	however	ADV
cusj-5649	27	12	all	all	DET
cusj-5649	27	13	three	three	NUM
cusj-5649	27	14	forms	form	NOUN
cusj-5649	27	15	are	be	AUX
cusj-5649	27	16	extremely	extremely	ADV
cusj-5649	27	17	infectious	infectious	ADJ
cusj-5649	27	18	.	.	PUNCT
cusj-5649	28	1	wild	wild	ADJ
cusj-5649	28	2	polioviruses	poliovirus	NOUN
cusj-5649	28	3	can	can	AUX
cusj-5649	28	4	be	be	AUX
cusj-5649	28	5	found	find	VERB
cusj-5649	28	6	in	in	ADP
cusj-5649	28	7	approximately	approximately	ADV
cusj-5649	28	8	10	10	NUM
cusj-5649	28	9	countries	country	NOUN
cusj-5649	28	10	.	.	PUNCT
cusj-5649	29	1	pv1	pv1	NOUN
cusj-5649	29	2	is	be	AUX
cusj-5649	29	3	highly	highly	ADV
cusj-5649	29	4	localized	localized	ADJ
cusj-5649	29	5	to	to	ADP
cusj-5649	29	6	regions	region	NOUN
cusj-5649	29	7	in	in	ADP
cusj-5649	29	8	india	india	PROPN
cusj-5649	29	9	,	,	PUNCT
cusj-5649	29	10	pakistan	pakistan	PROPN
cusj-5649	29	11	,	,	PUNCT
cusj-5649	29	12	afghanistan	afghanistan	PROPN
cusj-5649	29	13	,	,	PUNCT
cusj-5649	29	14	and	and	CCONJ
cusj-5649	29	15	egypt	egypt	PROPN
cusj-5649	29	16	,	,	PUNCT
cusj-5649	29	17	but	but	CCONJ
cusj-5649	29	18	following	follow	VERB
cusj-5649	29	19	outbreaks	outbreak	NOUN
cusj-5649	29	20	of	of	ADP
cusj-5649	29	21	poliomyelitis	poliomyelitis	NOUN
cusj-5649	29	22	in	in	ADP
cusj-5649	29	23	2003–2004	2003–2004	NUM
cusj-5649	29	24	it	it	PRON
cusj-5649	29	25	remains	remain	VERB
cusj-5649	29	26	widespread	widespread	ADJ
cusj-5649	29	27	in	in	ADP
cusj-5649	29	28	west	west	NOUN
cusj-5649	29	29	and	and	CCONJ
cusj-5649	29	30	central	central	PROPN
cusj-5649	29	31	africa	africa	PROPN
cusj-5649	29	32	.	.	PUNCT
cusj-5649	30	1	wild	wild	ADJ
cusj-5649	30	2	poliovirus	poliovirus	NOUN
cusj-5649	30	3	type	type	NOUN
cusj-5649	30	4	2	2	NUM
cusj-5649	30	5	has	have	AUX
cusj-5649	30	6	probably	probably	ADV
cusj-5649	30	7	been	be	AUX
cusj-5649	30	8	eradicated	eradicate	VERB
cusj-5649	30	9	;	;	PUNCT
cusj-5649	30	10	it	it	PRON
cusj-5649	30	11	was	be	AUX
cusj-5649	30	12	last	last	ADV
cusj-5649	30	13	detected	detect	VERB
cusj-5649	30	14	in	in	ADP
cusj-5649	30	15	october	october	PROPN
cusj-5649	30	16	1999	1999	NUM
cusj-5649	30	17	in	in	ADP
cusj-5649	30	18	uttar	uttar	PROPN
cusj-5649	30	19	pradesh	pradesh	PROPN
cusj-5649	30	20	,	,	PUNCT
cusj-5649	30	21	india	india	PROPN
cusj-5649	30	22	.	.	PUNCT
cusj-5649	31	1	wild	wild	ADJ
cusj-5649	31	2	pv3	pv3	NOUN
cusj-5649	31	3	is	be	AUX
cusj-5649	31	4	found	find	VERB
cusj-5649	31	5	in	in	ADP
cusj-5649	31	6	parts	part	NOUN
cusj-5649	31	7	of	of	ADP
cusj-5649	31	8	only	only	ADV
cusj-5649	31	9	#	#	SYM
cusj-5649	31	10	ve	ve	NOUN
cusj-5649	31	11	countries	country	NOUN
cusj-5649	31	12	(	(	PUNCT
cusj-5649	31	13	nigeria	nigeria	PROPN
cusj-5649	31	14	,	,	PUNCT
cusj-5649	31	15	niger	niger	PROPN
cusj-5649	31	16	,	,	PUNCT
cusj-5649	31	17	pakistan	pakistan	PROPN
cusj-5649	31	18	,	,	PUNCT
cusj-5649	31	19	india	india	PROPN
cusj-5649	31	20	,	,	PUNCT
cusj-5649	31	21	and	and	CCONJ
cusj-5649	31	22	sudan	sudan	PROPN
cusj-5649	31	23	)	)	PUNCT
cusj-5649	31	24	(	(	PUNCT
cusj-5649	31	25	merrill	merrill	NOUN
cusj-5649	31	26	,	,	PUNCT
cusj-5649	31	27	2004	2004	NUM
cusj-5649	31	28	)	)	PUNCT
cusj-5649	31	29	.	.	PUNCT
cusj-5649	32	1	poliovirus	poliovirus	NOUN
cusj-5649	32	2	,	,	PUNCT
cusj-5649	32	3	like	like	ADP
cusj-5649	32	4	other	other	ADJ
cusj-5649	32	5	picornaviruses	picornavirus	NOUN
cusj-5649	32	6	,	,	PUNCT
cusj-5649	32	7	is	be	AUX
cusj-5649	32	8	characterized	characterize	VERB
cusj-5649	32	9	by	by	ADP
cusj-5649	32	10	a	a	DET
cusj-5649	32	11	single	single	ADJ
cusj-5649	32	12	positive	positive	ADJ
cusj-5649	32	13	strand	strand	NOUN
cusj-5649	32	14	genomic	genomic	NOUN
cusj-5649	32	15	rna	rna	PROPN
cusj-5649	32	16	.	.	PUNCT
cusj-5649	33	1	infection	infection	NOUN
cusj-5649	33	2	occurs	occur	VERB
cusj-5649	33	3	via	via	ADP
cusj-5649	33	4	the	the	DET
cusj-5649	33	5	fecal	fecal	ADJ
cusj-5649	33	6	-	-	PUNCT
cusj-5649	33	7	oral	oral	ADJ
cusj-5649	33	8	route	route	NOUN
cusj-5649	33	9	;	;	PUNCT
cusj-5649	33	10	meaning	mean	VERB
cusj-5649	33	11	that	that	SCONJ
cusj-5649	33	12	one	one	PRON
cusj-5649	33	13	ingests	ingest	VERB
cusj-5649	33	14	the	the	DET
cusj-5649	33	15	virus	virus	NOUN
cusj-5649	33	16	,	,	PUNCT
cusj-5649	33	17	which	which	PRON
cusj-5649	33	18	then	then	ADV
cusj-5649	33	19	replicates	replicate	VERB
cusj-5649	33	20	within	within	ADP
cusj-5649	33	21	the	the	DET
cusj-5649	33	22	alimentary	alimentary	ADJ
cusj-5649	33	23	tract	tract	NOUN
cusj-5649	33	24	.	.	PUNCT
cusj-5649	34	1	in	in	ADP
cusj-5649	34	2	95	95	NUM
cusj-5649	34	3	%	%	NOUN
cusj-5649	34	4	of	of	ADP
cusj-5649	34	5	cases	case	NOUN
cusj-5649	34	6	only	only	ADV
cusj-5649	34	7	a	a	DET
cusj-5649	34	8	primary	primary	ADJ
cusj-5649	34	9	,	,	PUNCT
cusj-5649	34	10	transient	transient	ADJ
cusj-5649	34	11	presence	presence	NOUN
cusj-5649	34	12	of	of	ADP
cusj-5649	34	13	the	the	DET
cusj-5649	34	14	virus	virus	NOUN
cusj-5649	34	15	in	in	ADP
cusj-5649	34	16	the	the	DET
cusj-5649	34	17	bloodstream	bloodstream	NOUN
cusj-5649	34	18	occurs	occur	VERB
cusj-5649	34	19	(	(	PUNCT
cusj-5649	34	20	called	call	VERB
cusj-5649	34	21	a	a	DET
cusj-5649	34	22	viremia	viremia	NOUN
cusj-5649	34	23	)	)	PUNCT
cusj-5649	34	24	and	and	CCONJ
cusj-5649	34	25	the	the	DET
cusj-5649	34	26	poliovirus	poliovirus	NOUN
cusj-5649	34	27	infection	infection	NOUN
cusj-5649	34	28	is	be	AUX
cusj-5649	34	29	asymptomatic	asymptomatic	ADJ
cusj-5649	34	30	.	.	PUNCT
cusj-5649	35	1	in	in	ADP
cusj-5649	35	2	about	about	ADV
cusj-5649	35	3	5	5	NUM
cusj-5649	35	4	%	%	NOUN
cusj-5649	35	5	of	of	ADP
cusj-5649	35	6	cases	case	NOUN
cusj-5649	35	7	,	,	PUNCT
cusj-5649	35	8	the	the	DET
cusj-5649	35	9	virus	virus	NOUN
cusj-5649	35	10	spreads	spread	VERB
cusj-5649	35	11	,	,	PUNCT
cusj-5649	35	12	and	and	CCONJ
cusj-5649	35	13	replicates	replicate	NOUN
cusj-5649	35	14	in	in	ADP
cusj-5649	35	15	other	other	ADJ
cusj-5649	35	16	sites	site	NOUN
cusj-5649	35	17	such	such	ADJ
cusj-5649	35	18	as	as	ADP
cusj-5649	35	19	brown	brown	ADJ
cusj-5649	35	20	fat	fat	NOUN
cusj-5649	35	21	,	,	PUNCT
cusj-5649	35	22	the	the	DET
cusj-5649	35	23	reticuloendothelial	reticuloendothelial	ADJ
cusj-5649	35	24	tissues	tissue	NOUN
cusj-5649	35	25	,	,	PUNCT
cusj-5649	35	26	and	and	CCONJ
cusj-5649	35	27	muscle	muscle	NOUN
cusj-5649	35	28	.	.	PUNCT
cusj-5649	36	1	"	"	PUNCT
cusj-5649	36	2	is	be	AUX
cusj-5649	36	3	sustained	sustain	VERB
cusj-5649	36	4	replication	replication	NOUN
cusj-5649	36	5	causes	cause	VERB
cusj-5649	36	6	a	a	DET
cusj-5649	36	7	secondary	secondary	ADJ
cusj-5649	36	8	viremia	viremia	NOUN
cusj-5649	36	9	,	,	PUNCT
cusj-5649	36	10	and	and	CCONJ
cusj-5649	36	11	leads	lead	VERB
cusj-5649	36	12	to	to	ADP
cusj-5649	36	13	the	the	DET
cusj-5649	36	14	development	development	NOUN
cusj-5649	36	15	of	of	ADP
cusj-5649	36	16	minor	minor	ADJ
cusj-5649	36	17	symptoms	symptom	NOUN
cusj-5649	36	18	such	such	ADJ
cusj-5649	36	19	as	as	ADP
cusj-5649	36	20	fever	fever	NOUN
cusj-5649	36	21	,	,	PUNCT
cusj-5649	36	22	headache	headache	NOUN
cusj-5649	36	23	and	and	CCONJ
cusj-5649	36	24	sore	sore	ADJ
cusj-5649	36	25	throat	throat	NOUN
cusj-5649	36	26	.	.	PUNCT
cusj-5649	37	1	paralytic	paralytic	ADJ
cusj-5649	37	2	poliomyelitis	poliomyelitis	PROPN
cusj-5649	37	3	occurs	occur	VERB
cusj-5649	37	4	in	in	ADP
cusj-5649	37	5	less	less	ADJ
cusj-5649	37	6	than	than	ADP
cusj-5649	37	7	1	1	NUM
cusj-5649	37	8	%	%	NOUN
cusj-5649	37	9	of	of	ADP
cusj-5649	37	10	poliovirus	poliovirus	NOUN
cusj-5649	37	11	infections	infection	NOUN
cusj-5649	37	12	.	.	PUNCT
cusj-5649	38	1	paralytic	paralytic	ADJ
cusj-5649	38	2	disease	disease	NOUN
cusj-5649	38	3	occurs	occur	VERB
cusj-5649	38	4	when	when	SCONJ
cusj-5649	38	5	the	the	DET
cusj-5649	38	6	virus	virus	NOUN
cusj-5649	38	7	enters	enter	VERB
cusj-5649	38	8	the	the	DET
cusj-5649	38	9	central	central	ADJ
cusj-5649	38	10	nervous	nervous	ADJ
cusj-5649	38	11	system	system	NOUN
cusj-5649	38	12	(	(	PUNCT
cusj-5649	38	13	cns	cns	NOUN
cusj-5649	38	14	)	)	PUNCT
cusj-5649	38	15	and	and	CCONJ
cusj-5649	38	16	replicates	replicate	NOUN
cusj-5649	38	17	in	in	ADP
cusj-5649	38	18	motor	motor	NOUN
cusj-5649	38	19	neurons	neuron	NOUN
cusj-5649	38	20	within	within	ADP
cusj-5649	38	21	the	the	DET
cusj-5649	38	22	spinal	spinal	NOUN
cusj-5649	38	23	cord	cord	NOUN
cusj-5649	38	24	,	,	PUNCT
cusj-5649	38	25	brain	brain	NOUN
cusj-5649	38	26	stem	stem	NOUN
cusj-5649	38	27	,	,	PUNCT
cusj-5649	38	28	or	or	CCONJ
cusj-5649	38	29	motor	motor	NOUN
cusj-5649	38	30	cortex	cortex	NOUN
cusj-5649	38	31	,	,	PUNCT
cusj-5649	38	32	resulting	result	VERB
cusj-5649	38	33	in	in	ADP
cusj-5649	38	34	the	the	DET
cusj-5649	38	35	selective	selective	ADJ
cusj-5649	38	36	destruction	destruction	NOUN
cusj-5649	38	37	of	of	ADP
cusj-5649	38	38	motor	motor	NOUN
cusj-5649	38	39	neurons	neuron	NOUN
cusj-5649	38	40	;	;	PUNCT
cusj-5649	38	41	leading	lead	VERB
cusj-5649	38	42	to	to	ADP
cusj-5649	38	43	either	either	CCONJ
cusj-5649	38	44	temporary	temporary	ADJ
cusj-5649	38	45	or	or	CCONJ
cusj-5649	38	46	permanent	permanent	ADJ
cusj-5649	38	47	paralysis	paralysis	NOUN
cusj-5649	38	48	and	and	CCONJ
cusj-5649	38	49	,	,	PUNCT
cusj-5649	38	50	in	in	ADP
cusj-5649	38	51	rare	rare	ADJ
cusj-5649	38	52	cases	case	NOUN
cusj-5649	38	53	,	,	PUNCT
cusj-5649	38	54	to	to	ADP
cusj-5649	38	55	respiratory	respiratory	ADJ
cusj-5649	38	56	arrest	arrest	NOUN
cusj-5649	38	57	and	and	CCONJ
cusj-5649	38	58	death	death	NOUN
cusj-5649	38	59	(	(	PUNCT
cusj-5649	38	60	pliaka	pliaka	NOUN
cusj-5649	38	61	,	,	PUNCT
cusj-5649	38	62	2007	2007	NUM
cusj-5649	38	63	)	)	PUNCT
cusj-5649	38	64	.	.	PUNCT
cusj-5649	39	1	"	"	PUNCT
cusj-5649	39	2	ere	ere	PROPN
cusj-5649	39	3	are	be	AUX
cusj-5649	39	4	two	two	NUM
cusj-5649	39	5	key	key	ADJ
cusj-5649	39	6	mechanism	mechanism	NOUN
cusj-5649	39	7	by	by	ADP
cusj-5649	39	8	which	which	PRON
cusj-5649	39	9	poliovirus	poliovirus	NOUN
cusj-5649	39	10	evades	evade	VERB
cusj-5649	39	11	the	the	DET
cusj-5649	39	12	immune	immune	ADJ
cusj-5649	39	13	system	system	NOUN
cusj-5649	39	14	.	.	PUNCT
cusj-5649	40	1	first	first	ADV
cusj-5649	40	2	,	,	PUNCT
cusj-5649	40	3	it	it	PRON
cusj-5649	40	4	is	be	AUX
cusj-5649	40	5	capable	capable	ADJ
cusj-5649	40	6	of	of	ADP
cusj-5649	40	7	surviving	survive	VERB
cusj-5649	40	8	the	the	DET
cusj-5649	40	9	highly	highly	ADV
cusj-5649	40	10	acidic	acidic	ADJ
cusj-5649	40	11	conditions	condition	NOUN
cusj-5649	40	12	of	of	ADP
cusj-5649	40	13	the	the	DET
cusj-5649	40	14	gastrointestinal	gastrointestinal	ADJ
cusj-5649	40	15	tract	tract	NOUN
cusj-5649	40	16	,	,	PUNCT
cusj-5649	40	17	allowing	allow	VERB
cusj-5649	40	18	the	the	DET
cusj-5649	40	19	virus	virus	NOUN
cusj-5649	40	20	to	to	PART
cusj-5649	40	21	infect	infect	VERB
cusj-5649	40	22	the	the	DET
cusj-5649	40	23	host	host	NOUN
cusj-5649	40	24	and	and	CCONJ
cusj-5649	40	25	spread	spread	VERB
cusj-5649	40	26	throughout	throughout	ADP
cusj-5649	40	27	the	the	DET
cusj-5649	40	28	body	body	NOUN
cusj-5649	40	29	via	via	ADP
cusj-5649	40	30	the	the	DET
cusj-5649	40	31	lymphatic	lymphatic	ADJ
cusj-5649	40	32	system	system	NOUN
cusj-5649	40	33	.	.	PUNCT
cusj-5649	41	1	second	second	ADJ
cusj-5649	41	2	,	,	PUNCT
cusj-5649	41	3	because	because	SCONJ
cusj-5649	41	4	it	it	PRON
cusj-5649	41	5	can	can	AUX
cusj-5649	41	6	replicate	replicate	VERB
cusj-5649	41	7	very	very	ADV
cusj-5649	41	8	quickly	quickly	ADV
cusj-5649	41	9	,	,	PUNCT
cusj-5649	41	10	the	the	DET
cusj-5649	41	11	virus	virus	NOUN
cusj-5649	41	12	overwhelms	overwhelm	VERB
cusj-5649	41	13	the	the	DET
cusj-5649	41	14	host	host	NOUN
cusj-5649	41	15	organs	organ	NOUN
cusj-5649	41	16	before	before	SCONJ
cusj-5649	41	17	an	an	DET
cusj-5649	41	18	immune	immune	ADJ
cusj-5649	41	19	response	response	NOUN
cusj-5649	41	20	can	can	AUX
cusj-5649	41	21	be	be	AUX
cusj-5649	41	22	mounted	mount	VERB
cusj-5649	41	23	.	.	PUNCT
cusj-5649	42	1	in	in	ADP
cusj-5649	42	2	addition	addition	NOUN
cusj-5649	42	3	,	,	PUNCT
cusj-5649	42	4	there	there	PRON
cusj-5649	42	5	are	be	VERB
cusj-5649	42	6	more	more	ADJ
cusj-5649	42	7	than	than	ADP
cusj-5649	42	8	two	two	NUM
cusj-5649	42	9	such	such	ADJ
cusj-5649	42	10	mechanisms	mechanism	NOUN
cusj-5649	42	11	;	;	PUNCT
cusj-5649	42	12	additional	additional	ADJ
cusj-5649	42	13	ones	one	NOUN
cusj-5649	42	14	include	include	VERB
cusj-5649	42	15	inhibition	inhibition	NOUN
cusj-5649	42	16	of	of	ADP
cusj-5649	42	17	rna	rna	NOUN
cusj-5649	42	18	and	and	CCONJ
cusj-5649	42	19	protein	protein	NOUN
cusj-5649	42	20	synthesis	synthesis	NOUN
cusj-5649	42	21	,	,	PUNCT
cusj-5649	42	22	and	and	CCONJ
cusj-5649	42	23	inhibition	inhibition	NOUN
cusj-5649	42	24	of	of	ADP
cusj-5649	42	25	protein	protein	NOUN
cusj-5649	42	26	secretion	secretion	NOUN
cusj-5649	42	27	,	,	PUNCT
cusj-5649	42	28	both	both	PRON
cusj-5649	42	29	of	of	ADP
cusj-5649	42	30	which	which	PRON
cusj-5649	42	31	interfere	interfere	VERB
cusj-5649	42	32	with	with	ADP
cusj-5649	42	33	the	the	DET
cusj-5649	42	34	ifn	ifn	PROPN
cusj-5649	42	35	respsonse	respsonse	NOUN
cusj-5649	42	36	.	.	PUNCT
cusj-5649	43	1	fully	fully	ADV
cusj-5649	43	2	assembled	assemble	VERB
cusj-5649	43	3	poliovirus	poliovirus	NOUN
cusj-5649	43	4	leaves	leave	VERB
cusj-5649	43	5	the	the	DET
cusj-5649	43	6	con#nes	con#ne	NOUN
cusj-5649	43	7	poliovirus	poliovirus	NOUN
cusj-5649	43	8	receptor	receptor	NOUN
cusj-5649	43	9	cd155	cd155	NOUN
cusj-5649	43	10	over	over	ADP
cusj-5649	43	11	-	-	PUNCT
cusj-5649	43	12	expression	expression	NOUN
cusj-5649	43	13	e!ect	e!ect	PROPN
cusj-5649	43	14	on	on	ADP
cusj-5649	43	15	migration	migration	NOUN
cusj-5649	43	16	in	in	ADP
cusj-5649	43	17	c6	c6	PROPN
cusj-5649	43	18	glioma	glioma	NOUN
cusj-5649	43	19	cells	cell	NOUN
cusj-5649	43	20	zahra	zahra	PROPN
cusj-5649	43	21	bhaiwala1	bhaiwala1	PROPN
cusj-5649	43	22	,	,	PUNCT
cusj-5649	43	23	*	*	PROPN
cusj-5649	43	24	,	,	PUNCT
cusj-5649	43	25	christine	christine	PROPN
cusj-5649	43	26	marshall2	marshall2	PROPN
cusj-5649	44	1	1columbia	1columbia	NUM
cusj-5649	44	2	college	college	PROPN
cusj-5649	44	3	,	,	PUNCT
cusj-5649	44	4	columbia	columbia	PROPN
cusj-5649	44	5	university	university	PROPN
cusj-5649	44	6	,	,	PUNCT
cusj-5649	44	7	new	new	PROPN
cusj-5649	44	8	york	york	PROPN
cusj-5649	44	9	,	,	PUNCT
cusj-5649	44	10	ny	ny	PROPN
cusj-5649	44	11	10027	10027	NUM
cusj-5649	44	12	,	,	PUNCT
cusj-5649	44	13	2phillips	2phillips	NUM
cusj-5649	44	14	academy	academy	NOUN
cusj-5649	44	15	,	,	PUNCT
cusj-5649	44	16	andover	andover	PROPN
cusj-5649	44	17	,	,	PUNCT
cusj-5649	44	18	ma	ma	PROPN
cusj-5649	44	19	,	,	PUNCT
cusj-5649	44	20	01810	01810	NUM
cusj-5649	45	1	abstract	abstract	ADJ
cusj-5649	45	2	cell	cell	NOUN
cusj-5649	45	3	migration	migration	NOUN
cusj-5649	45	4	plays	play	VERB
cusj-5649	45	5	a	a	DET
cusj-5649	45	6	key	key	ADJ
cusj-5649	45	7	role	role	NOUN
cusj-5649	45	8	in	in	ADP
cusj-5649	45	9	brain	brain	NOUN
cusj-5649	45	10	cancer	cancer	NOUN
cusj-5649	45	11	invasion	invasion	NOUN
cusj-5649	45	12	,	,	PUNCT
cusj-5649	45	13	an	an	DET
cusj-5649	45	14	early	early	ADJ
cusj-5649	45	15	step	step	NOUN
cusj-5649	45	16	in	in	ADP
cusj-5649	45	17	metastasis	metastasis	NOUN
cusj-5649	45	18	,	,	PUNCT
cusj-5649	45	19	and	and	CCONJ
cusj-5649	45	20	proteins	protein	NOUN
cusj-5649	45	21	that	that	PRON
cusj-5649	45	22	regulate	regulate	VERB
cusj-5649	45	23	migration	migration	NOUN
cusj-5649	45	24	are	be	AUX
cusj-5649	45	25	often	often	ADV
cusj-5649	45	26	up	up	ADV
cusj-5649	45	27	-	-	PUNCT
cusj-5649	45	28	regulated	regulate	VERB
cusj-5649	45	29	in	in	ADP
cusj-5649	45	30	tumor	tumor	NOUN
cusj-5649	45	31	cells	cell	NOUN
cusj-5649	45	32	.	.	PUNCT
cusj-5649	46	1	the	the	DET
cusj-5649	46	2	poliovirus	poliovirus	NOUN
cusj-5649	46	3	receptor	receptor	NOUN
cusj-5649	46	4	cd155	cd155	NOUN
cusj-5649	46	5	has	have	AUX
cusj-5649	46	6	recently	recently	ADV
cusj-5649	46	7	been	be	AUX
cusj-5649	46	8	shown	show	VERB
cusj-5649	46	9	to	to	PART
cusj-5649	46	10	affect	affect	VERB
cusj-5649	46	11	migration	migration	NOUN
cusj-5649	46	12	levels	level	NOUN
cusj-5649	46	13	of	of	ADP
cusj-5649	46	14	select	select	ADJ
cusj-5649	46	15	malignant	malignant	ADJ
cusj-5649	46	16	glioma	glioma	NOUN
cusj-5649	46	17	strains	strain	NOUN
cusj-5649	46	18	,	,	PUNCT
cusj-5649	46	19	fueling	fuel	VERB
cusj-5649	46	20	the	the	DET
cusj-5649	46	21	exploration	exploration	NOUN
cusj-5649	46	22	of	of	ADP
cusj-5649	46	23	treating	treat	VERB
cusj-5649	46	24	brain	brain	NOUN
cusj-5649	46	25	cancer	cancer	NOUN
cusj-5649	46	26	with	with	ADP
cusj-5649	46	27	oncolytic	oncolytic	ADJ
cusj-5649	46	28	virus	virus	NOUN
cusj-5649	46	29	recombinants	recombinant	NOUN
cusj-5649	46	30	.	.	PUNCT
cusj-5649	47	1	in	in	ADP
cusj-5649	47	2	the	the	DET
cusj-5649	47	3	beginning	begin	VERB
cusj-5649	47	4	phase	phase	NOUN
cusj-5649	47	5	of	of	ADP
cusj-5649	47	6	experimentation	experimentation	NOUN
cusj-5649	47	7	,	,	PUNCT
cusj-5649	47	8	we	we	PRON
cusj-5649	47	9	analyzed	analyze	VERB
cusj-5649	47	10	the	the	DET
cusj-5649	47	11	migratory	migratory	ADJ
cusj-5649	47	12	behavior	behavior	NOUN
cusj-5649	47	13	of	of	ADP
cusj-5649	47	14	control	control	PROPN
cusj-5649	47	15	c6	c6	PROPN
cusj-5649	47	16	gliomas	glioma	VERB
cusj-5649	47	17	through	through	ADP
cusj-5649	47	18	two	two	NUM
cusj-5649	47	19	rounds	round	NOUN
cusj-5649	47	20	of	of	ADP
cusj-5649	47	21	[	[	X
cusj-5649	47	22	yhuzäs[ly	yhuzäs[ly	PROPN
cusj-5649	47	23	�	�	PROPN
cusj-5649	47	24	hzzh`z	hzzh`z	NOUN
cusj-5649	47	25	�	�	PROPN
cusj-5649	47	26	�	�	PROPN
cusj-5649	47	27	0u	0u	PROPN
cusj-5649	47	28	�	�	PROPN
cusj-5649	47	29	vykly	vykly	NOUN
cusj-5649	47	30	�	�	PROPN
cusj-5649	47	31	[v	[v	X
cusj-5649	47	32	�	�	NOUN
cusj-5649	47	33	l_wsvyl	l_wsvyl	NOUN
cusj-5649	47	34	�	�	PROPN
cusj-5649	47	35	[ol	[ol	SYM
cusj-5649	47	36	�	�	PROPN
cusj-5649	47	37	m\uj[pvu	m\uj[pvu	PROPN
cusj-5649	47	38	�	�	PROPN
cusj-5649	47	39	vm	vm	PROPN
cusj-5649	47	40	�	�	PROPN
cusj-5649	47	41	*+	*+	SYM
cusj-5649	47	42	�	�	PROPN
cusj-5649	47	43	�	�	PROPN
cusj-5649	47	44	�	�	PROPN
cusj-5649	47	45	�	�	PROPN
cusj-5649	47	46	pu	pu	PROPN
cusj-5649	47	47	�	�	PROPN
cusj-5649	47	48	nspvth	nspvth	PROPN
cusj-5649	47	49	�	�	PROPN
cusj-5649	47	50	tpnyh[pvu	tpnyh[pvu	NOUN
cusj-5649	47	51	�	�	PROPN
cusj-5649	47	52	�	�	PROPN
cusj-5649	47	53	^l	^l	VERB
cusj-5649	47	54	�	�	PROPN
cusj-5649	47	55	[olu	[olu	PROPN
cusj-5649	47	56	�	�	PROPN
cusj-5649	47	57	jvuk\j[lk	jvuk\j[lk	ADJ
cusj-5649	47	58	�	�	PROPN
cusj-5649	47	59	[^v	[^v	NOUN
cusj-5649	47	60	�	�	PROPN
cusj-5649	47	61	v]ly	v]ly	ADP
cusj-5649	47	62	�	�	PROPN
cusj-5649	47	63	l_wylzzpvu	l_wylzzpvu	ADJ
cusj-5649	47	64	�	�	PROPN
cusj-5649	47	65	experiments	experiment	NOUN
cusj-5649	47	66	with	with	ADP
cusj-5649	47	67	the	the	DET
cusj-5649	47	68	use	use	NOUN
cusj-5649	47	69	of	of	ADP
cusj-5649	47	70	a	a	DET
cusj-5649	47	71	full	full	ADJ
cusj-5649	47	72	-	-	PUNCT
cusj-5649	47	73	length	length	NOUN
cusj-5649	47	74	cdna	cdna	NOUN
cusj-5649	47	75	expression	expression	NOUN
cusj-5649	47	76	vector	vector	NOUN
cusj-5649	47	77	and	and	CCONJ
cusj-5649	47	78	compared	compare	VERB
cusj-5649	47	79	the	the	DET
cusj-5649	47	80	resulting	result	VERB
cusj-5649	47	81	migration	migration	NOUN
cusj-5649	47	82	rates	rate	NOUN
cusj-5649	47	83	to	to	PART
cusj-5649	47	84	control	control	VERB
cusj-5649	47	85	kh[h	kh[h	PROPN
cusj-5649	47	86	�	�	PROPN
cusj-5649	47	87	�	�	PROPN
cusj-5649	47	88	>l	>l	PROPN
cusj-5649	47	89	�	�	PROPN
cusj-5649	47	90	mv\uk	mv\uk	NOUN
cusj-5649	47	91	�	�	PROPN
cusj-5649	47	92	[oh[	[oh[	SYM
cusj-5649	47	93	�	�	PROPN
cusj-5649	47	94	hu	hu	PROPN
cusj-5649	47	95	�	�	PROPN
cusj-5649	47	96	h]lyhnl	h]lyhnl	PROPN
cusj-5649	47	97	�	�	PROPN
cusj-5649	47	98	vm	vm	PROPN
cusj-5649	47	99	�	�	PROPN
cusj-5649	47	100	�	�	PROPN
cusj-5649	47	101	�	�	PROPN
cusj-5649	47	102	�	�	PROPN
cusj-5649	47	103	�	�	PROPN
cusj-5649	47	104	�	�	PROPN
cusj-5649	47	105	�	�	PROPN
cusj-5649	47	106	�	�	PROPN
cusj-5649	47	107	jvu[yvs	jvu[yvs	PROPN
cusj-5649	47	108	�	�	PROPN
cusj-5649	47	109	jlssz	jlssz	PROPN
cusj-5649	47	110	�	�	PROPN
cusj-5649	47	111	jyvzz	jyvzz	PROPN
cusj-5649	47	112	�	�	PROPN
cusj-5649	47	113	v\y	v\y	PROPN
cusj-5649	47	114	�	�	PROPN
cusj-5649	47	115	[yhuzäs[lyz	[yhuzäs[lyz	PART
cusj-5649	47	116	�	�	PROPN
cusj-5649	47	117	hm[ly	hm[ly	PROPN
cusj-5649	47	118	�	�	PROPN
cusj-5649	47	119	�	�	PROPN
cusj-5649	47	120	�	�	PROPN
cusj-5649	47	121	�	�	PROPN
cusj-5649	47	122	�	�	PROPN
cusj-5649	47	123	ov\yz	ov\yz	PROPN
cusj-5649	47	124	�	�	PROPN
cusj-5649	47	125	�	�	PROPN
cusj-5649	47	126	huk	huk	PROPN
cusj-5649	47	127	�	�	PROPN
cusj-5649	47	128	hu	hu	PROPN
cusj-5649	47	129	�	�	PROPN
cusj-5649	47	130	h]lyhnl	h]lyhnl	PROPN
cusj-5649	47	131	�	�	PROPN
cusj-5649	47	132	vm	vm	PROPN
cusj-5649	47	133	�	�	PROPN
cusj-5649	47	134	�	�	PROPN
cusj-5649	47	135	�	�	PROPN
cusj-5649	47	136	�	�	PROPN
cusj-5649	47	137	�	�	PROPN
cusj-5649	47	138	�	�	PROPN
cusj-5649	47	139	�	�	PROPN
cusj-5649	47	140	jlssz	jlssz	NOUN
cusj-5649	47	141	�	�	PROPN
cusj-5649	48	1	[	[	X
cusj-5649	48	2	yhuzmlj[lk	yhuzmlj[lk	PROPN
cusj-5649	48	3	�	�	PROPN
cusj-5649	48	4	^p[o	^p[o	NOUN
cusj-5649	48	5	�	�	PROPN
cusj-5649	48	6	[ol	[ol	SYM
cusj-5649	48	7	�	�	PROPN
cusj-5649	48	8	7=9	7=9	NUM
cusj-5649	48	9	�	�	PROPN
cusj-5649	48	10	l_wylzzpvu	l_wylzzpvu	PROPN
cusj-5649	48	11	�	�	PROPN
cusj-5649	48	12	]lj[vy	]lj[vy	ADJ
cusj-5649	48	13	�	�	PROPN
cusj-5649	48	14	�	�	PROPN
cusj-5649	48	15	6\y	6\y	PROPN
cusj-5649	48	16	�	�	PROPN
cusj-5649	48	17	ylz\s[z	ylz\s[z	NOUN
cusj-5649	48	18	�	�	PROPN
cusj-5649	48	19	ylålj[lk	ylålj[lk	PROPN
cusj-5649	48	20	�	�	PROPN
cusj-5649	48	21	h	h	PROPN
cusj-5649	48	22	�	�	PROPN
cusj-5649	48	23	�	�	PROPN
cusj-5649	48	24	�	�	PROPN
cusj-5649	48	25	�	�	PROPN
cusj-5649	48	26	�	�	PROPN
cusj-5649	48	27	�	�	PROPN
cusj-5649	48	28	�	�	PROPN
cusj-5649	48	29	pujylhzl	pujylhzl	PROPN
cusj-5649	48	30	�	�	PROPN
cusj-5649	48	31	pu	pu	PROPN
cusj-5649	48	32	�	�	PROPN
cusj-5649	48	33	jlss	jlss	PROPN
cusj-5649	48	34	�	�	PROPN
cusj-5649	48	35	tpnyh[pvu	tpnyh[pvu	PROPN
cusj-5649	48	36	�	�	PROPN
cusj-5649	48	37	k\l	k\l	PROPN
cusj-5649	48	38	�	�	PROPN
cusj-5649	48	39	[v	[v	X
cusj-5649	48	40	�	�	PROPN
cusj-5649	48	41	hu	hu	PROPN
cusj-5649	48	42	�	�	PROPN
cusj-5649	48	43	pujylhzlk	pujylhzlk	PROPN
cusj-5649	48	44	�	�	PROPN
cusj-5649	48	45	wylzlujl	wylzlujl	PROPN
cusj-5649	48	46	�	�	PROPN
cusj-5649	48	47	vm	vm	PROPN
cusj-5649	48	48	�	�	PROPN
cusj-5649	48	49	[ol	[ol	SYM
cusj-5649	48	50	�	�	PROPN
cusj-5649	48	51	wyv[lpu	wyv[lpu	PROPN
cusj-5649	48	52	�	�	PROPN
cusj-5649	48	53	*+	*+	SYM
cusj-5649	48	54	�	�	PROPN
cusj-5649	48	55	�	�	PROPN
cusj-5649	48	56	�	�	PROPN
cusj-5649	48	57	�	�	PROPN
cusj-5649	48	58	�	�	PROPN
cusj-5649	48	59	0u	0u	PROPN
cusj-5649	48	60	�	�	PROPN
cusj-5649	48	61	vykly	vykly	NOUN
cusj-5649	48	62	�	�	PROPN
cusj-5649	48	63	[v	[v	X
cusj-5649	48	64	�	�	PROPN
cusj-5649	48	65	jvuäyt	jvuäyt	PROPN
cusj-5649	48	66	�	�	PROPN
cusj-5649	48	67	[oh[	[oh[	SYM
cusj-5649	48	68	�	�	PROPN
cusj-5649	48	69	*+	*+	SYM
cusj-5649	48	70	�	�	PROPN
cusj-5649	48	71	�	�	PROPN
cusj-5649	48	72	�	�	PROPN
cusj-5649	48	73	�	�	PROPN
cusj-5649	48	74	^hz	^hz	PROPN
cusj-5649	48	75	�	�	PROPN
cusj-5649	48	76	l_wylzzlk	l_wylzzlk	PROPN
cusj-5649	48	77	�	�	PROPN
cusj-5649	48	78	pu	pu	PROPN
cusj-5649	48	79	�	�	PROPN
cusj-5649	48	80	[ol	[ol	PROPN
cusj-5649	48	81	�	�	PROPN
cusj-5649	48	82	yh[	yh[	SYM
cusj-5649	48	83	�	�	PROPN
cusj-5649	48	84	*	*	PUNCT
cusj-5649	48	85	�	�	PROPN
cusj-5649	48	86	z	z	PROPN
cusj-5649	48	87	�	�	PROPN
cusj-5649	48	88	�	�	PROPN
cusj-5649	48	89	^l	^l	VERB
cusj-5649	48	90	�	�	PROPN
cusj-5649	48	91	z\izlx\lu[s`	z\izlx\lu[s`	PROPN
cusj-5649	48	92	�	�	PROPN
cusj-5649	48	93	jvuk\j[lk	jvuk\j[lk	ADJ
cusj-5649	48	94	�	�	PROPN
cusj-5649	48	95	two	two	NUM
cusj-5649	48	96	western	western	ADJ
cusj-5649	48	97	blots	blot	NOUN
cusj-5649	48	98	:	:	PUNCT
cusj-5649	48	99	one	one	NUM
cusj-5649	48	100	comparing	compare	VERB
cusj-5649	48	101	control	control	NOUN
cusj-5649	48	102	c6s	c6s	PROPN
cusj-5649	48	103	and	and	CCONJ
cusj-5649	48	104	transfected	transfecte	VERB
cusj-5649	48	105	c6s	c6s	PROPN
cusj-5649	48	106	,	,	PUNCT
cusj-5649	48	107	and	and	CCONJ
cusj-5649	48	108	the	the	DET
cusj-5649	48	109	other	other	ADJ
cusj-5649	48	110	running	running	NOUN
cusj-5649	48	111	control	control	NOUN
cusj-5649	48	112	c6s	c6s	PROPN
cusj-5649	48	113	next	next	ADJ
cusj-5649	48	114	to	to	ADP
cusj-5649	48	115	a	a	DET
cusj-5649	48	116	human	human	ADJ
cusj-5649	48	117	u87	u87	ADJ
cusj-5649	48	118	glioma	glioma	NOUN
cusj-5649	48	119	control	control	NOUN
cusj-5649	48	120	cell	cell	NOUN
cusj-5649	48	121	line	line	NOUN
cusj-5649	48	122	.	.	PUNCT
cusj-5649	49	1	the	the	DET
cusj-5649	49	2	blots	blot	NOUN
cusj-5649	49	3	establish	establish	VERB
cusj-5649	49	4	that	that	SCONJ
cusj-5649	49	5	cd155	cd155	PROPN
cusj-5649	49	6	is	be	AUX
cusj-5649	49	7	indeed	indeed	ADV
cusj-5649	49	8	present	present	ADJ
cusj-5649	49	9	in	in	ADP
cusj-5649	49	10	both	both	PRON
cusj-5649	49	11	of	of	ADP
cusj-5649	49	12	these	these	DET
cusj-5649	49	13	human	human	ADJ
cusj-5649	49	14	and	and	CCONJ
cusj-5649	49	15	rat	rat	NOUN
cusj-5649	49	16	strains	strain	NOUN
cusj-5649	49	17	of	of	ADP
cusj-5649	49	18	glioma	glioma	NOUN
cusj-5649	49	19	,	,	PUNCT
cusj-5649	49	20	and	and	CCONJ
cusj-5649	49	21	that	that	SCONJ
cusj-5649	49	22	our	our	PRON
cusj-5649	49	23	over	over	NOUN
cusj-5649	49	24	-	-	PUNCT
cusj-5649	49	25	expression	expression	NOUN
cusj-5649	49	26	was	be	AUX
cusj-5649	49	27	successful	successful	ADJ
cusj-5649	49	28	.	.	PUNCT
cusj-5649	50	1	key	key	ADJ
cusj-5649	50	2	words	word	NOUN
cusj-5649	50	3	:	:	PUNCT
cusj-5649	50	4	glioblastoma	glioblastoma	NOUN
cusj-5649	50	5	multiforme	multiforme	NOUN
cusj-5649	50	6	;	;	PUNCT
cusj-5649	50	7	tumor	tumor	NOUN
cusj-5649	50	8	migration	migration	NOUN
cusj-5649	50	9	;	;	PUNCT
cusj-5649	50	10	poliovirus	poliovirus	NOUN
cusj-5649	50	11	receptor	receptor	NOUN
cusj-5649	50	12	cd155	cd155	PROPN
cusj-5649	50	13	;	;	PUNCT
cusj-5649	50	14	protein	protein	NOUN
cusj-5649	50	15	over	over	ADP
cusj-5649	50	16	-	-	PUNCT
cusj-5649	50	17	expression	expression	NOUN
cusj-5649	50	18	.	.	PUNCT
cusj-5649	51	1	introduction	introduction	NOUN
cusj-5649	51	2	after	after	SCONJ
cusj-5649	51	3	the	the	DET
cusj-5649	51	4	human	human	ADJ
cusj-5649	51	5	brain	brain	NOUN
cusj-5649	51	6	completes	complete	VERB
cusj-5649	51	7	its	its	PRON
cusj-5649	51	8	development	development	NOUN
cusj-5649	51	9	soon	soon	ADV
cusj-5649	51	10	after	after	ADP
cusj-5649	51	11	birth	birth	NOUN
cusj-5649	51	12	,	,	PUNCT
cusj-5649	51	13	the	the	DET
cusj-5649	51	14	vast	vast	ADJ
cusj-5649	51	15	majority	majority	NOUN
cusj-5649	51	16	of	of	ADP
cusj-5649	51	17	its	its	PRON
cusj-5649	51	18	cells	cell	NOUN
cusj-5649	51	19	enter	enter	VERB
cusj-5649	51	20	the	the	DET
cusj-5649	51	21	g0	g0	ADJ
cusj-5649	51	22	phase	phase	NOUN
cusj-5649	51	23	,	,	PUNCT
cusj-5649	51	24	in	in	ADP
cusj-5649	51	25	which	which	PRON
cusj-5649	51	26	they	they	PRON
cusj-5649	51	27	never	never	ADV
cusj-5649	51	28	divide	divide	VERB
cusj-5649	51	29	again	again	ADV
cusj-5649	51	30	.	.	PUNCT
cusj-5649	52	1	one	one	NUM
cusj-5649	52	2	exception	exception	NOUN
cusj-5649	52	3	to	to	ADP
cusj-5649	52	4	this	this	DET
cusj-5649	52	5	rule	rule	NOUN
cusj-5649	52	6	is	be	AUX
cusj-5649	52	7	when	when	SCONJ
cusj-5649	52	8	a	a	DET
cusj-5649	52	9	brain	brain	NOUN
cusj-5649	52	10	tumor	tumor	NOUN
cusj-5649	52	11	develops	develop	VERB
cusj-5649	52	12	as	as	ADP
cusj-5649	52	13	a	a	DET
cusj-5649	52	14	result	result	NOUN
cusj-5649	52	15	of	of	ADP
cusj-5649	52	16	abnormal	abnormal	ADJ
cusj-5649	52	17	,	,	PUNCT
cusj-5649	52	18	unregulated	unregulated	ADJ
cusj-5649	52	19	growth	growth	NOUN
cusj-5649	52	20	of	of	ADP
cusj-5649	52	21	cells	cell	NOUN
cusj-5649	52	22	.	.	PUNCT
cusj-5649	53	1	"	"	PUNCT
cusj-5649	53	2	e	e	X
cusj-5649	53	3	atypical	atypical	ADJ
cusj-5649	53	4	brain	brain	NOUN
cusj-5649	53	5	cells	cell	NOUN
cusj-5649	53	6	re	re	VERB
cusj-5649	53	7	-	-	VERB
cusj-5649	53	8	enter	enter	VERB
cusj-5649	53	9	the	the	DET
cusj-5649	53	10	cell	cell	NOUN
cusj-5649	53	11	cycle	cycle	NOUN
cusj-5649	53	12	because	because	SCONJ
cusj-5649	53	13	of	of	ADP
cusj-5649	53	14	alterations	alteration	NOUN
cusj-5649	53	15	in	in	ADP
cusj-5649	53	16	any	any	PRON
cusj-5649	53	17	of	of	ADP
cusj-5649	53	18	a	a	DET
cusj-5649	53	19	large	large	ADJ
cusj-5649	53	20	number	number	NOUN
cusj-5649	53	21	of	of	ADP
cusj-5649	53	22	genes	gene	NOUN
cusj-5649	53	23	that	that	PRON
cusj-5649	53	24	control	control	VERB
cusj-5649	53	25	cell	cell	NOUN
cusj-5649	53	26	division	division	NOUN
cusj-5649	53	27	and	and	CCONJ
cusj-5649	53	28	growth	growth	NOUN
cusj-5649	53	29	.	.	PUNCT
cusj-5649	54	1	astrocytomas	astrocytoma	NOUN
cusj-5649	54	2	and	and	CCONJ
cusj-5649	54	3	oligodendrogliomas	oligodendroglioma	NOUN
cusj-5649	54	4	are	be	AUX
cusj-5649	54	5	types	type	NOUN
cusj-5649	54	6	of	of	ADP
cusj-5649	54	7	gliomas	glioma	NOUN
cusj-5649	54	8	that	that	PRON
cusj-5649	54	9	are	be	AUX
cusj-5649	54	10	the	the	DET
cusj-5649	54	11	most	most	ADV
cusj-5649	54	12	common	common	ADJ
cusj-5649	54	13	primary	primary	ADJ
cusj-5649	54	14	tumors	tumor	NOUN
cusj-5649	54	15	of	of	ADP
cusj-5649	54	16	the	the	DET
cusj-5649	54	17	adult	adult	NOUN
cusj-5649	54	18	brain	brain	NOUN
cusj-5649	54	19	.	.	PUNCT
cusj-5649	55	1	primary	primary	ADJ
cusj-5649	55	2	brain	brain	NOUN
cusj-5649	55	3	tumors	tumor	NOUN
cusj-5649	55	4	arise	arise	VERB
cusj-5649	55	5	from	from	ADP
cusj-5649	55	6	cells	cell	NOUN
cusj-5649	55	7	of	of	ADP
cusj-5649	55	8	the	the	DET
cusj-5649	55	9	brain	brain	NOUN
cusj-5649	55	10	itself	itself	PRON
cusj-5649	55	11	rather	rather	ADV
cusj-5649	55	12	than	than	ADP
cusj-5649	55	13	traveling	travel	VERB
cusj-5649	55	14	,	,	PUNCT
cusj-5649	55	15	or	or	CCONJ
cusj-5649	55	16	metastasizing	metastasizing	NOUN
cusj-5649	55	17	,	,	PUNCT
cusj-5649	55	18	to	to	ADP
cusj-5649	55	19	the	the	DET
cusj-5649	55	20	brain	brain	NOUN
cusj-5649	55	21	from	from	ADP
cusj-5649	55	22	another	another	DET
cusj-5649	55	23	location	location	NOUN
cusj-5649	55	24	in	in	ADP
cusj-5649	55	25	the	the	DET
cusj-5649	55	26	body	body	NOUN
cusj-5649	55	27	like	like	ADP
cusj-5649	55	28	other	other	ADJ
cusj-5649	55	29	known	know	VERB
cusj-5649	55	30	forms	form	NOUN
cusj-5649	55	31	of	of	ADP
cusj-5649	55	32	cancer	cancer	NOUN
cusj-5649	55	33	.	.	PUNCT
cusj-5649	56	1	tumors	tumor	NOUN
cusj-5649	56	2	are	be	AUX
cusj-5649	56	3	generally	generally	ADV
cusj-5649	56	4	classi#ed	classi#ed	ADJ
cusj-5649	56	5	in	in	ADP
cusj-5649	56	6	four	four	NUM
cusj-5649	56	7	grades	grade	NOUN
cusj-5649	56	8	,	,	PUNCT
cusj-5649	56	9	with	with	ADP
cusj-5649	56	10	grade	grade	NOUN
cusj-5649	56	11	1	1	NUM
cusj-5649	56	12	being	be	AUX
cusj-5649	56	13	the	the	DET
cusj-5649	56	14	most	most	ADV
cusj-5649	56	15	benign	benign	ADJ
cusj-5649	56	16	and	and	CCONJ
cusj-5649	56	17	grade	grade	NOUN
cusj-5649	56	18	4	4	NUM
cusj-5649	56	19	being	be	AUX
cusj-5649	56	20	the	the	DET
cusj-5649	56	21	most	most	ADV
cusj-5649	56	22	malignant	malignant	ADJ
cusj-5649	56	23	.	.	PUNCT
cusj-5649	57	1	signs	sign	NOUN
cusj-5649	57	2	that	that	SCONJ
cusj-5649	57	3	the	the	DET
cusj-5649	57	4	tumor	tumor	NOUN
cusj-5649	57	5	is	be	AUX
cusj-5649	57	6	growing	grow	VERB
cusj-5649	57	7	rapidly	rapidly	ADV
cusj-5649	57	8	include	include	VERB
cusj-5649	57	9	cells	cell	NOUN
cusj-5649	57	10	undergoing	undergo	VERB
cusj-5649	57	11	division	division	NOUN
cusj-5649	57	12	(	(	PUNCT
cusj-5649	57	13	mitosis	mitosis	NOUN
cusj-5649	57	14	)	)	PUNCT
cusj-5649	57	15	,	,	PUNCT
cusj-5649	57	16	the	the	DET
cusj-5649	57	17	presence	presence	NOUN
cusj-5649	57	18	of	of	ADP
cusj-5649	57	19	newly	newly	ADV
cusj-5649	57	20	-	-	PUNCT
cusj-5649	57	21	formed	form	VERB
cusj-5649	57	22	blood	blood	NOUN
cusj-5649	57	23	vessels	vessel	NOUN
cusj-5649	57	24	(	(	PUNCT
cusj-5649	57	25	angiogenesis	angiogenesis	NOUN
cusj-5649	57	26	)	)	PUNCT
cusj-5649	57	27	,	,	PUNCT
cusj-5649	57	28	and	and	CCONJ
cusj-5649	57	29	evidence	evidence	NOUN
cusj-5649	57	30	that	that	SCONJ
cusj-5649	57	31	the	the	DET
cusj-5649	57	32	tumor	tumor	NOUN
cusj-5649	57	33	is	be	AUX
cusj-5649	57	34	outgrowing	outgrow	VERB
cusj-5649	57	35	its	its	PRON
cusj-5649	57	36	blood	blood	NOUN
cusj-5649	57	37	supply	supply	NOUN
cusj-5649	57	38	(	(	PUNCT
cusj-5649	57	39	necrosis	necrosis	NOUN
cusj-5649	57	40	)	)	PUNCT
cusj-5649	57	41	.	.	PUNCT
cusj-5649	58	1	typically	typically	ADV
cusj-5649	58	2	,	,	PUNCT
cusj-5649	58	3	malignant	malignant	ADJ
cusj-5649	58	4	gliomas	glioma	NOUN
cusj-5649	58	5	show	show	VERB
cusj-5649	58	6	an	an	DET
cusj-5649	58	7	area	area	NOUN
cusj-5649	58	8	of	of	ADP
cusj-5649	58	9	central	central	ADJ
cusj-5649	58	10	necrosis	necrosis	NOUN
cusj-5649	58	11	surrounded	surround	VERB
cusj-5649	58	12	by	by	ADP
cusj-5649	58	13	a	a	DET
cusj-5649	58	14	highly	highly	ADV
cusj-5649	58	15	cellular	cellular	ADJ
cusj-5649	58	16	rim	rim	NOUN
cusj-5649	58	17	of	of	ADP
cusj-5649	58	18	viable	viable	ADJ
cusj-5649	58	19	tumor	tumor	NOUN
cusj-5649	58	20	.	.	PUNCT
cusj-5649	59	1	malignant	malignant	ADJ
cusj-5649	59	2	gliomas	glioma	NOUN
cusj-5649	59	3	have	have	AUX
cusj-5649	59	4	remained	remain	VERB
cusj-5649	59	5	resistant	resistant	ADJ
cusj-5649	59	6	to	to	ADP
cusj-5649	59	7	therapy	therapy	NOUN
cusj-5649	59	8	and	and	CCONJ
cusj-5649	59	9	are	be	AUX
cusj-5649	59	10	capable	capable	ADJ
cusj-5649	59	11	of	of	ADP
cusj-5649	59	12	spreading	spread	VERB
cusj-5649	59	13	long	long	ADJ
cusj-5649	59	14	distances	distance	NOUN
cusj-5649	59	15	within	within	ADP
cusj-5649	59	16	the	the	DET
cusj-5649	59	17	brain	brain	NOUN
cusj-5649	59	18	(	(	PUNCT
cusj-5649	59	19	madsen	madsen	PROPN
cusj-5649	59	20	,	,	PUNCT
cusj-5649	59	21	2006	2006	NUM
cusj-5649	59	22	)	)	PUNCT
cusj-5649	59	23	.	.	PUNCT
cusj-5649	60	1	in	in	ADP
cusj-5649	60	2	glioblastoma	glioblastoma	NOUN
cusj-5649	60	3	multiforme	multiforme	NOUN
cusj-5649	60	4	(	(	PUNCT
cusj-5649	60	5	gbm	gbm	PROPN
cusj-5649	60	6	)	)	PUNCT
cusj-5649	60	7	,	,	PUNCT
cusj-5649	60	8	the	the	DET
cusj-5649	60	9	most	most	ADV
cusj-5649	60	10	aggressive	aggressive	ADJ
cusj-5649	60	11	form	form	NOUN
cusj-5649	60	12	of	of	ADP
cusj-5649	60	13	brain	brain	NOUN
cusj-5649	60	14	cancer	cancer	NOUN
cusj-5649	60	15	,	,	PUNCT
cusj-5649	60	16	tumor	tumor	NOUN
cusj-5649	60	17	cells	cell	NOUN
cusj-5649	60	18	disperse	disperse	VERB
cusj-5649	60	19	so	so	ADV
cusj-5649	60	20	extensively	extensively	ADV
cusj-5649	60	21	that	that	SCONJ
cusj-5649	60	22	common	common	ADJ
cusj-5649	60	23	treatment	treatment	NOUN
cusj-5649	60	24	approaches	approach	NOUN
cusj-5649	60	25	such	such	ADJ
cusj-5649	60	26	as	as	ADP
cusj-5649	60	27	surgical	surgical	ADJ
cusj-5649	60	28	resection	resection	NOUN
cusj-5649	60	29	or	or	CCONJ
cusj-5649	60	30	radiation	radiation	NOUN
cusj-5649	60	31	therapy	therapy	NOUN
cusj-5649	60	32	are	be	AUX
cusj-5649	60	33	not	not	PART
cusj-5649	60	34	e!ective	e!ective	ADJ
cusj-5649	60	35	in	in	ADP
cusj-5649	60	36	checking	check	VERB
cusj-5649	60	37	progression	progression	NOUN
cusj-5649	60	38	.	.	PUNCT
cusj-5649	61	1	unfortunately	unfortunately	ADV
cusj-5649	61	2	,	,	PUNCT
cusj-5649	61	3	signi#cant	signi#cant	NOUN
cusj-5649	61	4	in#ltration	in#ltration	NOUN
cusj-5649	61	5	of	of	ADP
cusj-5649	61	6	normal	normal	ADJ
cusj-5649	61	7	brain	brain	NOUN
cusj-5649	61	8	matter	matter	NOUN
cusj-5649	61	9	is	be	AUX
cusj-5649	61	10	not	not	PART
cusj-5649	61	11	limited	limit	VERB
cusj-5649	61	12	to	to	ADP
cusj-5649	61	13	the	the	DET
cusj-5649	61	14	most	most	ADV
cusj-5649	61	15	malignant	malignant	NOUN
cusj-5649	61	16	of	of	ADP
cusj-5649	61	17	tumors	tumor	NOUN
cusj-5649	61	18	.	.	PUNCT
cusj-5649	62	1	"	"	PUNCT
cusj-5649	62	2	e	e	X
cusj-5649	62	3	invasive	invasive	ADJ
cusj-5649	62	4	behavior	behavior	NOUN
cusj-5649	62	5	expressed	express	VERB
cusj-5649	62	6	by	by	ADP
cusj-5649	62	7	all	all	DET
cusj-5649	62	8	levels	level	NOUN
cusj-5649	62	9	of	of	ADP
cusj-5649	62	10	malignant	malignant	ADJ
cusj-5649	62	11	gliomas	glioma	NOUN
cusj-5649	62	12	has	have	AUX
cusj-5649	62	13	limited	limit	VERB
cusj-5649	62	14	the	the	DET
cusj-5649	62	15	e!ectiveness	e!ectiveness	NOUN
cusj-5649	62	16	of	of	ADP
cusj-5649	62	17	local	local	ADJ
cusj-5649	62	18	therapies	therapy	NOUN
cusj-5649	62	19	and	and	CCONJ
cusj-5649	62	20	contributes	contribute	VERB
cusj-5649	62	21	to	to	ADP
cusj-5649	62	22	the	the	DET
cusj-5649	62	23	high	high	ADJ
cusj-5649	62	24	mortality	mortality	NOUN
cusj-5649	62	25	rate	rate	NOUN
cusj-5649	62	26	seen	see	VERB
cusj-5649	62	27	in	in	ADP
cusj-5649	62	28	these	these	DET
cusj-5649	62	29	tumors	tumor	NOUN
cusj-5649	62	30	.	.	PUNCT
cusj-5649	63	1	"	"	PUNCT
cusj-5649	63	2	e	e	X
cusj-5649	63	3	position	position	NOUN
cusj-5649	63	4	of	of	ADP
cusj-5649	63	5	the	the	DET
cusj-5649	63	6	tumor	tumor	NOUN
cusj-5649	63	7	is	be	AUX
cusj-5649	63	8	also	also	ADV
cusj-5649	63	9	crucial	crucial	ADJ
cusj-5649	63	10	.	.	PUNCT
cusj-5649	64	1	brain	brain	NOUN
cusj-5649	64	2	stem	stem	NOUN
cusj-5649	64	3	gliomas	glioma	NOUN
cusj-5649	64	4	are	be	AUX
cusj-5649	64	5	particularly	particularly	ADV
cusj-5649	64	6	di%cult	di%cult	VERB
cusj-5649	64	7	to	to	PART
cusj-5649	64	8	treat	treat	VERB
cusj-5649	64	9	,	,	PUNCT
cusj-5649	64	10	regardless	regardless	ADV
cusj-5649	64	11	of	of	ADP
cusj-5649	64	12	their	their	PRON
cusj-5649	64	13	grade	grade	NOUN
cusj-5649	64	14	.	.	PUNCT
cusj-5649	65	1	"	"	PUNCT
cusj-5649	65	2	e	e	X
cusj-5649	65	3	brain	brain	NOUN
cusj-5649	65	4	stem	stem	NOUN
cusj-5649	65	5	is	be	AUX
cusj-5649	65	6	such	such	DET
cusj-5649	65	7	a	a	DET
cusj-5649	65	8	complicated	complicated	ADJ
cusj-5649	65	9	and	and	CCONJ
cusj-5649	65	10	delicate	delicate	ADJ
cusj-5649	65	11	part	part	NOUN
cusj-5649	65	12	of	of	ADP
cusj-5649	65	13	the	the	DET
cusj-5649	65	14	brain	brain	NOUN
cusj-5649	65	15	that	that	PRON
cusj-5649	65	16	completely	completely	ADV
cusj-5649	65	17	removing	remove	VERB
cusj-5649	65	18	the	the	DET
cusj-5649	65	19	tumor	tumor	NOUN
cusj-5649	65	20	is	be	AUX
cusj-5649	65	21	highly	highly	ADV
cusj-5649	65	22	unlikely	unlikely	ADJ
cusj-5649	65	23	.	.	PUNCT
cusj-5649	66	1	unfortunately	unfortunately	ADV
cusj-5649	66	2	,	,	PUNCT
cusj-5649	66	3	high	high	ADJ
cusj-5649	66	4	doses	dose	NOUN
cusj-5649	66	5	of	of	ADP
cusj-5649	66	6	radiation	radiation	NOUN
cusj-5649	66	7	are	be	AUX
cusj-5649	66	8	not	not	PART
cusj-5649	66	9	recommended	recommend	VERB
cusj-5649	66	10	for	for	ADP
cusj-5649	66	11	treatment	treatment	NOUN
cusj-5649	66	12	,	,	PUNCT
cusj-5649	66	13	as	as	SCONJ
cusj-5649	66	14	this	this	PRON
cusj-5649	66	15	may	may	AUX
cusj-5649	66	16	cause	cause	VERB
cusj-5649	66	17	too	too	ADV
cusj-5649	66	18	much	much	ADJ
cusj-5649	66	19	damage	damage	NOUN
cusj-5649	66	20	to	to	ADP
cusj-5649	66	21	the	the	DET
cusj-5649	66	22	normal	normal	ADJ
cusj-5649	66	23	brain	brain	NOUN
cusj-5649	66	24	stem	stem	NOUN
cusj-5649	66	25	(	(	PUNCT
cusj-5649	66	26	giese	giese	NOUN
cusj-5649	66	27	,	,	PUNCT
cusj-5649	66	28	2003	2003	NUM
cusj-5649	66	29	)	)	PUNCT
cusj-5649	66	30	.	.	PUNCT
cusj-5649	67	1	having	have	VERB
cusj-5649	67	2	an	an	DET
cusj-5649	67	3	agent	agent	NOUN
cusj-5649	67	4	that	that	PRON
cusj-5649	67	5	blocks	block	VERB
cusj-5649	67	6	migration	migration	NOUN
cusj-5649	67	7	is	be	AUX
cusj-5649	67	8	key	key	ADJ
cusj-5649	67	9	to	to	ADP
cusj-5649	67	10	managing	manage	VERB
cusj-5649	67	11	glioblastoma	glioblastoma	NOUN
cusj-5649	67	12	multiforme	multiforme	NOUN
cusj-5649	67	13	.	.	PUNCT
cusj-5649	68	1	interventions	intervention	NOUN
cusj-5649	68	2	to	to	PART
cusj-5649	68	3	control	control	VERB
cusj-5649	68	4	the	the	DET
cusj-5649	68	5	spreading	spreading	NOUN
cusj-5649	68	6	of	of	ADP
cusj-5649	68	7	glioblastoma	glioblastoma	NOUN
cusj-5649	68	8	multiforme	multiforme	NOUN
cusj-5649	68	9	have	have	VERB
cusj-5649	68	10	the	the	DET
cusj-5649	68	11	potential	potential	NOUN
cusj-5649	68	12	to	to	PART
cusj-5649	68	13	slow	slow	VERB
cusj-5649	68	14	the	the	DET
cusj-5649	68	15	clinical	clinical	ADJ
cusj-5649	68	16	course	course	NOUN
cusj-5649	68	17	of	of	ADP
cusj-5649	68	18	the	the	DET
cusj-5649	68	19	disease	disease	NOUN
cusj-5649	68	20	and	and	CCONJ
cusj-5649	68	21	improve	improve	VERB
cusj-5649	68	22	copyright	copyright	NOUN
cusj-5649	68	23	:	:	PUNCT
cusj-5649	68	24	©	©	PROPN
cusj-5649	68	25	2011	2011	NUM
cusj-5649	68	26	the	the	DET
cusj-5649	68	27	trustees	trustee	NOUN
cusj-5649	68	28	of	of	ADP
cusj-5649	68	29	columbia	columbia	PROPN
cusj-5649	68	30	university	university	PROPN
cusj-5649	68	31	,	,	PUNCT
cusj-5649	68	32	columbia	columbia	PROPN
cusj-5649	68	33	university	university	PROPN
cusj-5649	68	34	libraries	library	NOUN
cusj-5649	68	35	,	,	PUNCT
cusj-5649	68	36	some	some	DET
cusj-5649	68	37	rights	right	NOUN
cusj-5649	68	38	reserved	reserve	VERB
cusj-5649	68	39	,	,	PUNCT
cusj-5649	68	40	porter	porter	NOUN
cusj-5649	68	41	,	,	PUNCT
cusj-5649	68	42	et	et	PROPN
cusj-5649	68	43	al	al	PROPN
cusj-5649	68	44	.	.	PROPN
cusj-5649	68	45	received	receive	VERB
cusj-5649	68	46	jan	jan	PROPN
cusj-5649	68	47	.	.	PROPN
cusj-5649	68	48	2	2	NUM
cusj-5649	68	49	,	,	PUNCT
cusj-5649	68	50	2011	2011	NUM
cusj-5649	68	51	.	.	PUNCT
cusj-5649	69	1	accepted	accept	VERB
cusj-5649	69	2	jan	jan	PROPN
cusj-5649	69	3	.	.	PROPN
cusj-5649	69	4	26	26	NUM
cusj-5649	69	5	,	,	PUNCT
cusj-5649	69	6	2011	2011	NUM
cusj-5649	69	7	.	.	PUNCT
cusj-5649	70	1	published	publish	VERB
cusj-5649	70	2	april	april	PROPN
cusj-5649	70	3	1	1	NUM
cusj-5649	70	4	,	,	PUNCT
cusj-5649	70	5	2011	2011	NUM
cusj-5649	70	6	.	.	PUNCT
cusj-5649	71	1	*	*	PUNCT
cusj-5649	71	2	to	to	PART
cusj-5649	71	3	whom	whom	PRON
cusj-5649	71	4	correspondence	correspondence	NOUN
cusj-5649	71	5	should	should	AUX
cusj-5649	71	6	be	be	AUX
cusj-5649	71	7	addressed	address	VERB
cusj-5649	71	8	:	:	PUNCT
cusj-5649	71	9	columbia	columbia	PROPN
cusj-5649	71	10	college	college	PROPN
cusj-5649	71	11	,	,	PUNCT
cusj-5649	71	12	columbia	columbia	PROPN
cusj-5649	71	13	university	university	PROPN
cusj-5649	71	14	,	,	PUNCT
cusj-5649	71	15	new	new	PROPN
cusj-5649	71	16	york	york	PROPN
cusj-5649	71	17	,	,	PUNCT
cusj-5649	71	18	ny	ny	PROPN
cusj-5649	71	19	10027	10027	NUM
cusj-5649	71	20	.	.	PUNCT
cusj-5649	72	1	zsb2104@columbia.edu	zsb2104@columbia.edu	PROPN
cusj-5649	73	1	columbia	columbia	PROPN
cusj-5649	73	2	undergraduate	undergraduate	PROPN
cusj-5649	73	3	science	science	PROPN
cusj-5649	73	4	journal	journal	PROPN
cusj-5649	73	5	open	open	ADJ
cusj-5649	73	6	-	-	PUNCT
cusj-5649	73	7	access	access	NOUN
cusj-5649	73	8	publication	publication	NOUN
cusj-5649	73	9	|	|	ADV
cusj-5649	73	10	http://cusj.columbia.com	http://cusj.columbia.com	X
cusj-5649	73	11	44	44	NUM
cusj-5649	73	12	cusjvolume	cusjvolume	ADJ
cusj-5649	73	13	5spring	5spring	NUM
cusj-5649	73	14	2011	2011	NUM
cusj-5649	73	15	columbia	columbia	PROPN
cusj-5649	73	16	undergraduate	undergraduate	NOUN
cusj-5649	73	17	sci	sci	PROPN
cusj-5649	73	18	j	j	PROPN
cusj-5649	73	19	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	73	20	v	v	ADP
cusj-5649	73	21	ir	ir	PROPN
cusj-5649	74	1	o	o	NOUN
cusj-5649	75	1	lo	lo	NOUN
cusj-5649	76	1	g	g	PROPN
cusj-5649	76	2	y	y	PROPN
cusj-5649	76	3	cusjcolumbia	cusjcolumbia	ADJ
cusj-5649	76	4	undergraduate	undergraduate	NOUN
cusj-5649	76	5	science	science	NOUN
cusj-5649	76	6	journalresearch	journalresearch	NOUN
cusj-5649	76	7	articles	article	NOUN
cusj-5649	76	8	45cusj	45cusj	PROPN
cusj-5649	77	1	volume	volume	NOUN
cusj-5649	77	2	5spring	5spring	PROPN
cusj-5649	77	3	2011	2011	NUM
cusj-5649	78	1	columbia	columbia	PROPN
cusj-5649	78	2	undergraduate	undergraduate	NOUN
cusj-5649	78	3	sci	sci	PROPN
cusj-5649	78	4	j	j	PROPN
cusj-5649	78	5	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	78	6	v	v	ADP
cusj-5649	78	7	ir	ir	PROPN
cusj-5649	78	8	o	o	NOUN
cusj-5649	79	1	lo	lo	NOUN
cusj-5649	79	2	g	g	PROPN
cusj-5649	79	3	y	y	PROPN
cusj-5649	79	4	materials	material	NOUN
cusj-5649	79	5	and	and	CCONJ
cusj-5649	79	6	methods	method	NOUN
cusj-5649	79	7	somal	somal	NOUN
cusj-5649	79	8	entry	entry	NOUN
cusj-5649	79	9	site	site	NOUN
cusj-5649	79	10	(	(	PUNCT
cusj-5649	79	11	ires	ire	NOUN
cusj-5649	79	12	)	)	PUNCT
cusj-5649	79	13	within	within	ADP
cusj-5649	79	14	the	the	DET
cusj-5649	79	15	5	5	NUM
cusj-5649	79	16	’	'	PUNCT
cusj-5649	79	17	untranslated	untranslated	ADJ
cusj-5649	79	18	region	region	NOUN
cusj-5649	79	19	of	of	ADP
cusj-5649	79	20	the	the	DET
cusj-5649	79	21	viral	viral	ADJ
cusj-5649	79	22	genome	genome	NOUN
cusj-5649	79	23	,	,	PUNCT
cusj-5649	79	24	which	which	PRON
cusj-5649	79	25	is	be	AUX
cusj-5649	79	26	active	active	ADJ
cusj-5649	79	27	in	in	ADP
cusj-5649	79	28	cells	cell	NOUN
cusj-5649	79	29	of	of	ADP
cusj-5649	79	30	neuronal	neuronal	ADJ
cusj-5649	79	31	origin	origin	NOUN
cusj-5649	79	32	and	and	CCONJ
cusj-5649	79	33	allows	allow	VERB
cusj-5649	79	34	translation	translation	NOUN
cusj-5649	79	35	of	of	ADP
cusj-5649	79	36	the	the	DET
cusj-5649	79	37	viral	viral	ADJ
cusj-5649	79	38	genome	genome	NOUN
cusj-5649	79	39	without	without	ADP
cusj-5649	79	40	a	a	DET
cusj-5649	79	41	5	5	NUM
cusj-5649	79	42	’	'	PUNCT
cusj-5649	79	43	cap	cap	NOUN
cusj-5649	79	44	.	.	PUNCT
cusj-5649	80	1	non	non	ADJ
cusj-5649	80	2	-	-	ADJ
cusj-5649	80	3	transductional	transductional	ADJ
cusj-5649	80	4	targeting	targeting	NOUN
cusj-5649	80	5	involves	involve	NOUN
cusj-5649	80	6	altering	alter	VERB
cusj-5649	80	7	the	the	DET
cusj-5649	80	8	genome	genome	NOUN
cusj-5649	80	9	of	of	ADP
cusj-5649	80	10	the	the	DET
cusj-5649	80	11	virus	virus	NOUN
cusj-5649	80	12	so	so	SCONJ
cusj-5649	80	13	it	it	PRON
cusj-5649	80	14	can	can	AUX
cusj-5649	80	15	only	only	ADV
cusj-5649	80	16	replicate	replicate	VERB
cusj-5649	80	17	in	in	ADP
cusj-5649	80	18	cancer	cancer	NOUN
cusj-5649	80	19	cells	cell	NOUN
cusj-5649	80	20	.	.	PUNCT
cusj-5649	80	21	!	!	PUNCT
cusj-5649	81	1	is	be	AUX
cusj-5649	81	2	can	can	AUX
cusj-5649	81	3	be	be	AUX
cusj-5649	81	4	done	do	VERB
cusj-5649	81	5	by	by	ADP
cusj-5649	81	6	either	either	DET
cusj-5649	81	7	transcription	transcription	NOUN
cusj-5649	81	8	targeting	target	VERB
cusj-5649	81	9	,	,	PUNCT
cusj-5649	81	10	where	where	SCONJ
cusj-5649	81	11	genes	gene	NOUN
cusj-5649	81	12	essential	essential	ADJ
cusj-5649	81	13	for	for	ADP
cusj-5649	81	14	viral	viral	ADJ
cusj-5649	81	15	replication	replication	NOUN
cusj-5649	81	16	are	be	AUX
cusj-5649	81	17	placed	place	VERB
cusj-5649	81	18	under	under	ADP
cusj-5649	81	19	the	the	DET
cusj-5649	81	20	control	control	NOUN
cusj-5649	81	21	of	of	ADP
cusj-5649	81	22	a	a	DET
cusj-5649	81	23	tumor	tumor	NOUN
cusj-5649	81	24	-	-	PUNCT
cusj-5649	81	25	speci"c	speci"c	NOUN
cusj-5649	81	26	promoter	promoter	NOUN
cusj-5649	81	27	,	,	PUNCT
cusj-5649	81	28	or	or	CCONJ
cusj-5649	81	29	by	by	ADP
cusj-5649	81	30	attenuation	attenuation	NOUN
cusj-5649	81	31	,	,	PUNCT
cusj-5649	81	32	which	which	PRON
cusj-5649	81	33	involves	involve	VERB
cusj-5649	81	34	introducing	introduce	VERB
cusj-5649	81	35	deletions	deletion	NOUN
cusj-5649	81	36	into	into	ADP
cusj-5649	81	37	the	the	DET
cusj-5649	81	38	viral	viral	ADJ
cusj-5649	81	39	genome	genome	NOUN
cusj-5649	81	40	that	that	PRON
cusj-5649	81	41	eliminate	eliminate	VERB
cusj-5649	81	42	functions	function	NOUN
cusj-5649	81	43	that	that	PRON
cusj-5649	81	44	are	be	AUX
cusj-5649	81	45	dispensable	dispensable	ADJ
cusj-5649	81	46	in	in	ADP
cusj-5649	81	47	cancer	cancer	NOUN
cusj-5649	81	48	cells	cell	NOUN
cusj-5649	81	49	,	,	PUNCT
cusj-5649	81	50	but	but	CCONJ
cusj-5649	81	51	not	not	PART
cusj-5649	81	52	in	in	ADP
cusj-5649	81	53	normal	normal	ADJ
cusj-5649	81	54	cells	cell	NOUN
cusj-5649	81	55	.	.	PUNCT
cusj-5649	82	1	gromeier	gromei	ADJ
cusj-5649	82	2	et	et	PROPN
cusj-5649	82	3	al	al	PROPN
cusj-5649	82	4	.	.	PROPN
cusj-5649	82	5	replaced	replace	VERB
cusj-5649	82	6	the	the	DET
cusj-5649	82	7	normal	normal	ADJ
cusj-5649	82	8	poliovirus	poliovirus	NOUN
cusj-5649	82	9	ires	ire	NOUN
cusj-5649	82	10	with	with	ADP
cusj-5649	82	11	a	a	DET
cusj-5649	82	12	rhinovirus	rhinovirus	NOUN
cusj-5649	82	13	ires	ire	NOUN
cusj-5649	82	14	,	,	PUNCT
cusj-5649	82	15	altering	alter	VERB
cusj-5649	82	16	tissue	tissue	NOUN
cusj-5649	82	17	speci"city	speci"city	NOUN
cusj-5649	82	18	(	(	PUNCT
cusj-5649	82	19	gromeier	gromeier	NOUN
cusj-5649	82	20	,	,	PUNCT
cusj-5649	82	21	2000	2000	NUM
cusj-5649	82	22	)	)	PUNCT
cusj-5649	82	23	.	.	PUNCT
cusj-5649	82	24	!	!	PUNCT
cusj-5649	83	1	e	e	X
cusj-5649	83	2	resulting	result	VERB
cusj-5649	83	3	pv1(ripo	pv1(ripo	PROPN
cusj-5649	83	4	)	)	PUNCT
cusj-5649	83	5	virus	virus	NOUN
cusj-5649	83	6	was	be	AUX
cusj-5649	83	7	able	able	ADJ
cusj-5649	83	8	to	to	PART
cusj-5649	83	9	selectively	selectively	ADV
cusj-5649	83	10	destroy	destroy	VERB
cusj-5649	83	11	malignant	malignant	ADJ
cusj-5649	83	12	glioma	glioma	NOUN
cusj-5649	83	13	cells	cell	NOUN
cusj-5649	83	14	,	,	PUNCT
cusj-5649	83	15	while	while	SCONJ
cusj-5649	83	16	leaving	leave	VERB
cusj-5649	83	17	normal	normal	ADJ
cusj-5649	83	18	neuronal	neuronal	ADJ
cusj-5649	83	19	cells	cell	NOUN
cusj-5649	83	20	untouched	untouched	ADJ
cusj-5649	83	21	.	.	PUNCT
cusj-5649	84	1	although	although	SCONJ
cusj-5649	84	2	the	the	DET
cusj-5649	84	3	poliovirus	poliovirus	NOUN
cusj-5649	84	4	itself	itself	PRON
cusj-5649	84	5	has	have	AUX
cusj-5649	84	6	been	be	AUX
cusj-5649	84	7	demonstrated	demonstrate	VERB
cusj-5649	84	8	in	in	ADP
cusj-5649	84	9	previous	previous	ADJ
cusj-5649	84	10	studies	study	NOUN
cusj-5649	84	11	to	to	PART
cusj-5649	84	12	have	have	VERB
cusj-5649	84	13	an	an	DET
cusj-5649	84	14	oncolytic	oncolytic	ADJ
cusj-5649	84	15	e#ect	e#ect	ADJ
cusj-5649	84	16	in	in	ADP
cusj-5649	84	17	certain	certain	ADJ
cusj-5649	84	18	types	type	NOUN
cusj-5649	84	19	of	of	ADP
cusj-5649	84	20	gliomas	glioma	NOUN
cusj-5649	84	21	,	,	PUNCT
cusj-5649	84	22	it	it	PRON
cusj-5649	84	23	is	be	AUX
cusj-5649	84	24	still	still	ADV
cusj-5649	84	25	somewhat	somewhat	ADV
cusj-5649	84	26	unclear	unclear	ADJ
cusj-5649	84	27	what	what	PRON
cusj-5649	84	28	the	the	DET
cusj-5649	84	29	actual	actual	ADJ
cusj-5649	84	30	role	role	NOUN
cusj-5649	84	31	of	of	ADP
cusj-5649	84	32	the	the	DET
cusj-5649	84	33	receptor	receptor	NOUN
cusj-5649	84	34	cd155	cd155	PROPN
cusj-5649	84	35	might	might	AUX
cusj-5649	84	36	have	have	VERB
cusj-5649	84	37	,	,	PUNCT
cusj-5649	84	38	if	if	SCONJ
cusj-5649	84	39	any	any	PRON
cusj-5649	84	40	,	,	PUNCT
cusj-5649	84	41	in	in	ADP
cusj-5649	84	42	this	this	DET
cusj-5649	84	43	relatively	relatively	ADV
cusj-5649	84	44	new	new	ADJ
cusj-5649	84	45	discovery	discovery	NOUN
cusj-5649	84	46	of	of	ADP
cusj-5649	84	47	cancer	cancer	NOUN
cusj-5649	84	48	treatment	treatment	NOUN
cusj-5649	84	49	through	through	ADP
cusj-5649	84	50	viral	viral	ADJ
cusj-5649	84	51	infection	infection	NOUN
cusj-5649	84	52	.	.	PUNCT
cusj-5649	85	1	in	in	ADP
cusj-5649	85	2	glioblastoma	glioblastoma	NOUN
cusj-5649	85	3	,	,	PUNCT
cusj-5649	85	4	the	the	DET
cusj-5649	85	5	most	most	ADV
cusj-5649	85	6	aggressive	aggressive	ADJ
cusj-5649	85	7	form	form	NOUN
cusj-5649	85	8	of	of	ADP
cusj-5649	85	9	brain	brain	NOUN
cusj-5649	85	10	cancer	cancer	NOUN
cusj-5649	85	11	,	,	PUNCT
cusj-5649	85	12	tumor	tumor	NOUN
cusj-5649	85	13	cells	cell	NOUN
cusj-5649	85	14	disperse	disperse	VERB
cusj-5649	85	15	so	so	ADV
cusj-5649	85	16	extensively	extensively	ADV
cusj-5649	85	17	that	that	SCONJ
cusj-5649	85	18	current	current	ADJ
cusj-5649	85	19	treatment	treatment	NOUN
cusj-5649	85	20	approaches	approach	NOUN
cusj-5649	85	21	such	such	ADJ
cusj-5649	85	22	as	as	ADP
cusj-5649	85	23	surgical	surgical	ADJ
cusj-5649	85	24	resection	resection	NOUN
cusj-5649	85	25	or	or	CCONJ
cusj-5649	85	26	radiation	radiation	NOUN
cusj-5649	85	27	therapy	therapy	NOUN
cusj-5649	85	28	have	have	VERB
cusj-5649	85	29	little	little	ADJ
cusj-5649	85	30	e#ect	e#ect	ADJ
cusj-5649	85	31	in	in	ADP
cusj-5649	85	32	checking	check	VERB
cusj-5649	85	33	progression	progression	NOUN
cusj-5649	85	34	.	.	PUNCT
cusj-5649	85	35	!	!	PUNCT
cusj-5649	86	1	e	e	NOUN
cusj-5649	86	2	survival	survival	NOUN
cusj-5649	86	3	of	of	ADP
cusj-5649	86	4	patients	patient	NOUN
cusj-5649	86	5	with	with	ADP
cusj-5649	86	6	malignant	malignant	ADJ
cusj-5649	86	7	gliomas	glioma	NOUN
cusj-5649	86	8	,	,	PUNCT
cusj-5649	86	9	and	and	CCONJ
cusj-5649	86	10	a	a	DET
cusj-5649	86	11	median	median	ADJ
cusj-5649	86	12	survival	survival	NOUN
cusj-5649	86	13	time	time	NOUN
cusj-5649	86	14	of	of	ADP
cusj-5649	86	15	patients	patient	NOUN
cusj-5649	86	16	with	with	ADP
cusj-5649	86	17	malignant	malignant	ADJ
cusj-5649	86	18	gliomas	glioma	NOUN
cusj-5649	86	19	is	be	AUX
cusj-5649	86	20	still	still	ADV
cusj-5649	86	21	anticipated	anticipate	VERB
cusj-5649	86	22	as	as	ADP
cusj-5649	86	23	a	a	DET
cusj-5649	86	24	bleak	bleak	ADJ
cusj-5649	86	25	12	12	NUM
cusj-5649	86	26	to	to	PART
cusj-5649	86	27	14	14	NUM
cusj-5649	86	28	months	month	NOUN
cusj-5649	86	29	.	.	PUNCT
cusj-5649	87	1	invasive	invasive	ADJ
cusj-5649	87	2	cells	cell	NOUN
cusj-5649	87	3	remaining	remain	VERB
cusj-5649	87	4	after	after	SCONJ
cusj-5649	87	5	the	the	DET
cusj-5649	87	6	surgical	surgical	ADJ
cusj-5649	87	7	resection	resection	NOUN
cusj-5649	87	8	signi"cantly	signi"cantly	ADV
cusj-5649	87	9	contribute	contribute	VERB
cusj-5649	87	10	to	to	ADP
cusj-5649	87	11	the	the	DET
cusj-5649	87	12	demise	demise	NOUN
cusj-5649	87	13	of	of	ADP
cusj-5649	87	14	the	the	DET
cusj-5649	87	15	patient	patient	NOUN
cusj-5649	87	16	.	.	PUNCT
cusj-5649	88	1	any	any	DET
cusj-5649	88	2	successful	successful	ADJ
cusj-5649	88	3	treatment	treatment	NOUN
cusj-5649	88	4	will	will	AUX
cusj-5649	88	5	have	have	VERB
cusj-5649	88	6	to	to	PART
cusj-5649	88	7	treat	treat	VERB
cusj-5649	88	8	the	the	DET
cusj-5649	88	9	invasive	invasive	ADJ
cusj-5649	88	10	portion	portion	NOUN
cusj-5649	88	11	of	of	ADP
cusj-5649	88	12	the	the	DET
cusj-5649	88	13	tumor	tumor	NOUN
cusj-5649	88	14	and	and	CCONJ
cusj-5649	88	15	the	the	DET
cusj-5649	88	16	core	core	NOUN
cusj-5649	88	17	lesion	lesion	NOUN
cusj-5649	88	18	.	.	PUNCT
cusj-5649	89	1	speci"cally	speci"cally	ADV
cusj-5649	89	2	targeting	target	VERB
cusj-5649	89	3	invasive	invasive	ADJ
cusj-5649	89	4	glioma	glioma	NOUN
cusj-5649	89	5	cells	cell	NOUN
cusj-5649	89	6	remains	remain	VERB
cusj-5649	89	7	an	an	DET
cusj-5649	89	8	interesting	interesting	ADJ
cusj-5649	89	9	concept	concept	NOUN
cusj-5649	89	10	because	because	SCONJ
cusj-5649	89	11	invasiveness	invasiveness	NOUN
cusj-5649	89	12	must	must	AUX
cusj-5649	89	13	be	be	AUX
cusj-5649	89	14	a	a	DET
cusj-5649	89	15	common	common	ADJ
cusj-5649	89	16	characteristic	characteristic	NOUN
cusj-5649	89	17	of	of	ADP
cusj-5649	89	18	most	most	ADJ
cusj-5649	89	19	tumor	tumor	NOUN
cusj-5649	89	20	cells	cell	NOUN
cusj-5649	89	21	remaining	remain	VERB
cusj-5649	89	22	after	after	ADP
cusj-5649	89	23	surgical	surgical	ADJ
cusj-5649	89	24	resection	resection	NOUN
cusj-5649	89	25	.	.	PUNCT
cusj-5649	90	1	because	because	SCONJ
cusj-5649	90	2	it	it	PRON
cusj-5649	90	3	has	have	AUX
cusj-5649	90	4	been	be	AUX
cusj-5649	90	5	increasingly	increasingly	ADV
cusj-5649	90	6	shown	show	VERB
cusj-5649	90	7	that	that	SCONJ
cusj-5649	90	8	glioma	glioma	NOUN
cusj-5649	90	9	invasion	invasion	NOUN
cusj-5649	90	10	is	be	AUX
cusj-5649	90	11	regulated	regulate	VERB
cusj-5649	90	12	by	by	ADP
cusj-5649	90	13	distinct	distinct	ADJ
cusj-5649	90	14	trigger	trigger	NOUN
cusj-5649	90	15	mechanisms	mechanism	NOUN
cusj-5649	90	16	,	,	PUNCT
cusj-5649	90	17	downstream	downstream	ADJ
cusj-5649	90	18	e#ector	e#ector	NOUN
cusj-5649	90	19	molecules	molecule	NOUN
cusj-5649	90	20	of	of	ADP
cusj-5649	90	21	the	the	DET
cusj-5649	90	22	invasion	invasion	NOUN
cusj-5649	90	23	process	process	NOUN
cusj-5649	90	24	represent	represent	VERB
cusj-5649	90	25	the	the	DET
cusj-5649	90	26	best	good	ADJ
cusj-5649	90	27	treatment	treatment	NOUN
cusj-5649	90	28	targets	target	NOUN
cusj-5649	90	29	.	.	PUNCT
cusj-5649	91	1	it	it	PRON
cusj-5649	91	2	has	have	AUX
cusj-5649	91	3	been	be	AUX
cusj-5649	91	4	previously	previously	ADV
cusj-5649	91	5	found	find	VERB
cusj-5649	91	6	that	that	SCONJ
cusj-5649	91	7	cd155	cd155	PROPN
cusj-5649	91	8	/	/	SYM
cusj-5649	91	9	pvr	pvr	NOUN
cusj-5649	91	10	was	be	AUX
cusj-5649	91	11	highly	highly	ADV
cusj-5649	91	12	expressed	express	VERB
cusj-5649	91	13	in	in	ADP
cusj-5649	91	14	both	both	CCONJ
cusj-5649	91	15	u87	u87	ADJ
cusj-5649	91	16	human	human	ADJ
cusj-5649	91	17	glioma	glioma	NOUN
cusj-5649	91	18	cells	cell	NOUN
cusj-5649	91	19	and	and	CCONJ
cusj-5649	91	20	primary	primary	ADJ
cusj-5649	91	21	glioblastoma	glioblastoma	NOUN
cusj-5649	91	22	tumor	tumor	NOUN
cusj-5649	91	23	tissue	tissue	NOUN
cusj-5649	91	24	,	,	PUNCT
cusj-5649	91	25	and	and	CCONJ
cusj-5649	91	26	that	that	SCONJ
cusj-5649	91	27	inactivation	inactivation	NOUN
cusj-5649	91	28	of	of	ADP
cusj-5649	91	29	cd155	cd155	PROPN
cusj-5649	91	30	/	/	SYM
cusj-5649	91	31	pvr	pvr	NOUN
cusj-5649	91	32	reduced	reduce	VERB
cusj-5649	91	33	cell	cell	NOUN
cusj-5649	91	34	migration	migration	NOUN
cusj-5649	91	35	in	in	ADP
cusj-5649	91	36	vitro	vitro	X
cusj-5649	91	37	(	(	PUNCT
cusj-5649	91	38	sloan	sloan	NOUN
cusj-5649	91	39	,	,	PUNCT
cusj-5649	91	40	2005	2005	NUM
cusj-5649	91	41	)	)	PUNCT
cusj-5649	91	42	.	.	PUNCT
cusj-5649	91	43	!	!	PUNCT
cusj-5649	92	1	ese	ese	NOUN
cusj-5649	92	2	"	"	PUNCT
cusj-5649	92	3	ndings	nding	NOUN
cusj-5649	92	4	suggest	suggest	VERB
cusj-5649	92	5	a	a	DET
cusj-5649	92	6	novel	novel	ADJ
cusj-5649	92	7	role	role	NOUN
cusj-5649	92	8	for	for	ADP
cusj-5649	92	9	cd155	cd155	PROPN
cusj-5649	92	10	/	/	SYM
cusj-5649	92	11	pvr	pvr	NOUN
cusj-5649	92	12	in	in	ADP
cusj-5649	92	13	regulating	regulate	VERB
cusj-5649	92	14	motility	motility	NOUN
cusj-5649	92	15	and	and	CCONJ
cusj-5649	92	16	has	have	AUX
cusj-5649	92	17	prompted	prompt	VERB
cusj-5649	92	18	me	i	PRON
cusj-5649	92	19	to	to	PART
cusj-5649	92	20	explore	explore	VERB
cusj-5649	92	21	this	this	DET
cusj-5649	92	22	function	function	NOUN
cusj-5649	92	23	further	far	ADV
cusj-5649	92	24	in	in	ADP
cusj-5649	92	25	the	the	DET
cusj-5649	92	26	c6	c6	PROPN
cusj-5649	92	27	rat	rat	NOUN
cusj-5649	92	28	glioma	glioma	NOUN
cusj-5649	92	29	cells	cell	NOUN
cusj-5649	92	30	we	we	PRON
cusj-5649	92	31	have	have	VERB
cusj-5649	92	32	here	here	ADV
cusj-5649	92	33	in	in	ADP
cusj-5649	92	34	lab	lab	NOUN
cusj-5649	92	35	by	by	ADP
cusj-5649	92	36	conducting	conduct	VERB
cusj-5649	92	37	an	an	DET
cusj-5649	92	38	over	over	ADP
cusj-5649	92	39	-	-	PUNCT
cusj-5649	92	40	expression	expression	NOUN
cusj-5649	92	41	experiment	experiment	NOUN
cusj-5649	92	42	to	to	PART
cusj-5649	92	43	mirror	mirror	VERB
cusj-5649	92	44	the	the	DET
cusj-5649	92	45	relationship	relationship	NOUN
cusj-5649	92	46	that	that	PRON
cusj-5649	92	47	has	have	AUX
cusj-5649	92	48	been	be	AUX
cusj-5649	92	49	found	find	VERB
cusj-5649	92	50	in	in	ADP
cusj-5649	92	51	the	the	DET
cusj-5649	92	52	knockdown	knockdown	NOUN
cusj-5649	92	53	experiments	experiment	NOUN
cusj-5649	92	54	.	.	PUNCT
cusj-5649	93	1	cell	cell	NOUN
cusj-5649	93	2	culture	culture	NOUN
cusj-5649	93	3	c6	c6	PROPN
cusj-5649	93	4	rat	rat	NOUN
cusj-5649	93	5	glioma	glioma	NOUN
cusj-5649	93	6	cell	cell	NOUN
cusj-5649	93	7	lines	line	NOUN
cusj-5649	93	8	(	(	PUNCT
cusj-5649	93	9	canoll	canoll	NOUN
cusj-5649	93	10	lab	lab	PROPN
cusj-5649	93	11	,	,	PUNCT
cusj-5649	93	12	columbia	columbia	PROPN
cusj-5649	93	13	university	university	PROPN
cusj-5649	93	14	)	)	PUNCT
cusj-5649	93	15	were	be	AUX
cusj-5649	93	16	cultured	cultured	ADJ
cusj-5649	93	17	in	in	ADP
cusj-5649	93	18	dulbecco	dulbecco	NOUN
cusj-5649	93	19	’s	’s	PART
cusj-5649	93	20	modi"cation	modi"cation	NOUN
cusj-5649	93	21	of	of	ADP
cusj-5649	93	22	eagle	eagle	PROPN
cusj-5649	93	23	’s	’s	PART
cusj-5649	93	24	medium	medium	PROPN
cusj-5649	93	25	(	(	PUNCT
cusj-5649	93	26	dmem	dmem	ADJ
cusj-5649	93	27	)	)	PUNCT
cusj-5649	93	28	with	with	ADP
cusj-5649	93	29	4.5	4.5	NUM
cusj-5649	93	30	g	g	NOUN
cusj-5649	93	31	/	/	SYM
cusj-5649	93	32	l	l	NOUN
cusj-5649	93	33	glucose	glucose	NOUN
cusj-5649	93	34	,	,	PUNCT
cusj-5649	93	35	l	l	NOUN
cusj-5649	93	36	-	-	NOUN
cusj-5649	93	37	glutamine	glutamine	NOUN
cusj-5649	93	38	,	,	PUNCT
cusj-5649	93	39	and	and	CCONJ
cusj-5649	93	40	sodium	sodium	NOUN
cusj-5649	93	41	pyruvate	pyruvate	NOUN
cusj-5649	93	42	supplemented	supplement	VERB
cusj-5649	93	43	with	with	ADP
cusj-5649	93	44	10	10	NUM
cusj-5649	93	45	%	%	NOUN
cusj-5649	93	46	fetal	fetal	ADJ
cusj-5649	93	47	bovine	bovine	NOUN
cusj-5649	93	48	serum	serum	NOUN
cusj-5649	93	49	and	and	CCONJ
cusj-5649	93	50	1x	1x	NUM
cusj-5649	93	51	penn	penn	PROPN
cusj-5649	93	52	strep	strep	PROPN
cusj-5649	93	53	(	(	PUNCT
cusj-5649	93	54	mediatech	mediatech	NOUN
cusj-5649	93	55	)	)	PUNCT
cusj-5649	93	56	.	.	PUNCT
cusj-5649	94	1	cells	cell	NOUN
cusj-5649	94	2	were	be	AUX
cusj-5649	94	3	incubated	incubate	VERB
cusj-5649	94	4	at	at	ADP
cusj-5649	94	5	37	37	NUM
cusj-5649	94	6	°	°	ADP
cusj-5649	94	7	c	c	NOUN
cusj-5649	94	8	in	in	ADP
cusj-5649	94	9	a	a	DET
cusj-5649	94	10	napco	napco	ADJ
cusj-5649	94	11	series	series	NOUN
cusj-5649	94	12	8000	8000	NUM
cusj-5649	94	13	wj	wj	NOUN
cusj-5649	94	14	co2	co2	NOUN
cusj-5649	94	15	incubator	incubator	NOUN
cusj-5649	94	16	under	under	ADP
cusj-5649	94	17	a	a	DET
cusj-5649	94	18	humidi"ed	humidi"ed	ADJ
cusj-5649	94	19	5	5	NUM
cusj-5649	94	20	%	%	NOUN
cusj-5649	94	21	co2	co2	NOUN
cusj-5649	94	22	atmosphere	atmosphere	NOUN
cusj-5649	94	23	.	.	PUNCT
cusj-5649	95	1	cells	cell	NOUN
cusj-5649	95	2	were	be	AUX
cusj-5649	95	3	passaged	passage	VERB
cusj-5649	95	4	every	every	DET
cusj-5649	95	5	seven	seven	NUM
cusj-5649	95	6	days	day	NOUN
cusj-5649	95	7	onto	onto	ADP
cusj-5649	95	8	fresh	fresh	ADJ
cusj-5649	95	9	poly	poly	ADJ
cusj-5649	95	10	-	-	PUNCT
cusj-5649	95	11	l	l	NOUN
cusj-5649	95	12	-	-	PUNCT
cusj-5649	95	13	lysinecoated	lysinecoate	VERB
cusj-5649	95	14	t75	t75	NOUN
cusj-5649	95	15	$	$	SYM
cusj-5649	95	16	asks	ask	VERB
cusj-5649	95	17	,	,	PUNCT
cusj-5649	95	18	and	and	CCONJ
cusj-5649	95	19	medium	medium	NOUN
cusj-5649	95	20	was	be	AUX
cusj-5649	95	21	changed	change	VERB
cusj-5649	95	22	every	every	DET
cusj-5649	95	23	three	three	NUM
cusj-5649	95	24	days	day	NOUN
cusj-5649	95	25	.	.	PUNCT
cusj-5649	96	1	transfection	transfection	NOUN
cusj-5649	96	2	of	of	ADP
cusj-5649	96	3	cdna	cdna	PROPN
cusj-5649	96	4	expression	expression	NOUN
cusj-5649	96	5	vector	vector	NOUN
cusj-5649	96	6	we	we	PRON
cusj-5649	96	7	obtained	obtain	VERB
cusj-5649	96	8	glycerol	glycerol	NOUN
cusj-5649	96	9	stocks	stock	NOUN
cusj-5649	96	10	of	of	ADP
cusj-5649	96	11	e.	e.	PROPN
cusj-5649	96	12	coli	coli	PROPN
cusj-5649	96	13	transformed	transform	VERB
cusj-5649	96	14	with	with	ADP
cusj-5649	96	15	a	a	DET
cusj-5649	96	16	4.395	4.395	NUM
cusj-5649	96	17	kb	kb	PROPN
cusj-5649	96	18	pcmv	pcmv	NOUN
cusj-5649	96	19	-	-	PUNCT
cusj-5649	96	20	sport6	sport6	NOUN
cusj-5649	96	21	expression	expression	NOUN
cusj-5649	96	22	vector	vector	NOUN
cusj-5649	96	23	(	(	PUNCT
cusj-5649	96	24	image	image	NOUN
cusj-5649	96	25	i	i	NOUN
cusj-5649	96	26	d	d	NOUN
cusj-5649	96	27	:	:	PUNCT
cusj-5649	96	28	3902226	3902226	NUM
cusj-5649	96	29	,	,	PUNCT
cusj-5649	96	30	american	american	ADJ
cusj-5649	96	31	type	type	NOUN
cusj-5649	96	32	culture	culture	NOUN
cusj-5649	96	33	collection	collection	NOUN
cusj-5649	96	34	)	)	PUNCT
cusj-5649	96	35	,	,	PUNCT
cusj-5649	96	36	which	which	PRON
cusj-5649	96	37	used	use	VERB
cusj-5649	96	38	a	a	DET
cusj-5649	96	39	50	50	NUM
cusj-5649	96	40	µg/µl	µg/µl	NUM
cusj-5649	96	41	ampicillin	ampicillin	NOUN
cusj-5649	96	42	marker	marker	NOUN
cusj-5649	96	43	and	and	CCONJ
cusj-5649	96	44	was	be	AUX
cusj-5649	96	45	stored	store	VERB
cusj-5649	96	46	inde"nitely	inde"nitely	ADV
cusj-5649	96	47	at	at	ADP
cusj-5649	96	48	-80	-80	NOUN
cusj-5649	96	49	°	°	NOUN
cusj-5649	96	50	c	c	NOUN
cusj-5649	96	51	.	.	PUNCT
cusj-5649	97	1	dna	dna	PROPN
cusj-5649	97	2	was	be	AUX
cusj-5649	97	3	isolated	isolate	VERB
cusj-5649	97	4	according	accord	VERB
cusj-5649	97	5	to	to	ADP
cusj-5649	97	6	standard	standard	ADJ
cusj-5649	97	7	plasmid	plasmid	ADJ
cusj-5649	97	8	preparation	preparation	NOUN
cusj-5649	97	9	procedures	procedure	NOUN
cusj-5649	97	10	and	and	CCONJ
cusj-5649	97	11	absorbance	absorbance	NOUN
cusj-5649	97	12	was	be	AUX
cusj-5649	97	13	measured	measure	VERB
cusj-5649	97	14	at	at	ADP
cusj-5649	97	15	260	260	NUM
cusj-5649	97	16	nm	nm	NOUN
cusj-5649	97	17	via	via	ADP
cusj-5649	97	18	spectrophotometer	spectrophotometer	NOUN
cusj-5649	97	19	(	(	PUNCT
cusj-5649	97	20	biomate	biomate	NOUN
cusj-5649	97	21	)	)	PUNCT
cusj-5649	97	22	.	.	PUNCT
cusj-5649	98	1	one	one	NUM
cusj-5649	98	2	day	day	NOUN
cusj-5649	98	3	prior	prior	ADV
cusj-5649	98	4	to	to	ADP
cusj-5649	98	5	transfection	transfection	NOUN
cusj-5649	98	6	,	,	PUNCT
cusj-5649	98	7	the	the	DET
cusj-5649	98	8	cells	cell	NOUN
cusj-5649	98	9	were	be	AUX
cusj-5649	98	10	trypsinized	trypsinize	VERB
cusj-5649	98	11	from	from	ADP
cusj-5649	98	12	the	the	DET
cusj-5649	98	13	t75	t75	NOUN
cusj-5649	98	14	$	$	AUX
cusj-5649	98	15	ask	ask	VERB
cusj-5649	98	16	and	and	CCONJ
cusj-5649	98	17	added	add	VERB
cusj-5649	98	18	to	to	ADP
cusj-5649	98	19	10	10	NUM
cusj-5649	98	20	ml	ml	NOUN
cusj-5649	98	21	of	of	ADP
cusj-5649	98	22	growth	growth	NOUN
cusj-5649	98	23	medium	medium	NOUN
cusj-5649	98	24	.	.	PUNCT
cusj-5649	98	25	!	!	PUNCT
cusj-5649	99	1	e	e	NOUN
cusj-5649	99	2	mixture	mixture	NOUN
cusj-5649	99	3	was	be	AUX
cusj-5649	99	4	then	then	ADV
cusj-5649	99	5	spun	spin	VERB
cusj-5649	99	6	in	in	ADP
cusj-5649	99	7	a	a	DET
cusj-5649	99	8	tabletop	tabletop	NOUN
cusj-5649	99	9	centrifuge	centrifuge	NOUN
cusj-5649	99	10	(	(	PUNCT
cusj-5649	99	11	2000rpm	2000rpm	NUM
cusj-5649	99	12	for	for	ADP
cusj-5649	99	13	5	5	NUM
cusj-5649	99	14	minutes	minute	NOUN
cusj-5649	99	15	)	)	PUNCT
cusj-5649	99	16	and	and	CCONJ
cusj-5649	99	17	resuspended	resuspend	VERB
cusj-5649	99	18	in	in	ADP
cusj-5649	99	19	5	5	NUM
cusj-5649	99	20	ml	ml	NOUN
cusj-5649	99	21	of	of	ADP
cusj-5649	99	22	antibiotic	antibiotic	ADJ
cusj-5649	99	23	-	-	PUNCT
cusj-5649	99	24	free	free	ADJ
cusj-5649	99	25	growth	growth	NOUN
cusj-5649	99	26	medium	medium	NOUN
cusj-5649	99	27	.	.	PUNCT
cusj-5649	100	1	cells	cell	NOUN
cusj-5649	100	2	were	be	AUX
cusj-5649	100	3	triturated	triturate	VERB
cusj-5649	100	4	and	and	CCONJ
cusj-5649	100	5	then	then	ADV
cusj-5649	100	6	counted	count	VERB
cusj-5649	100	7	by	by	ADP
cusj-5649	100	8	inserting	insert	VERB
cusj-5649	100	9	10	10	NUM
cusj-5649	100	10	µl	µl	NOUN
cusj-5649	100	11	into	into	ADP
cusj-5649	100	12	a	a	DET
cusj-5649	100	13	hemocytometer	hemocytometer	NOUN
cusj-5649	100	14	and	and	CCONJ
cusj-5649	100	15	approximately	approximately	ADV
cusj-5649	100	16	5x105	5x105	NUM
cusj-5649	100	17	cells	cell	NOUN
cusj-5649	100	18	were	be	AUX
cusj-5649	100	19	plated	plate	VERB
cusj-5649	100	20	into	into	ADP
cusj-5649	100	21	60	60	NUM
cusj-5649	100	22	mm	mm	NOUN
cusj-5649	100	23	tissue	tissue	NOUN
cusj-5649	100	24	culture	culture	NOUN
cusj-5649	100	25	dishes	dish	NOUN
cusj-5649	100	26	containing	contain	VERB
cusj-5649	100	27	3	3	NUM
cusj-5649	100	28	ml	ml	NOUN
cusj-5649	100	29	of	of	ADP
cusj-5649	100	30	growth	growth	NOUN
cusj-5649	100	31	medium	medium	NOUN
cusj-5649	100	32	.	.	PUNCT
cusj-5649	101	1	in	in	ADP
cusj-5649	101	2	two	two	NUM
cusj-5649	101	3	separate	separate	ADJ
cusj-5649	101	4	sterile	sterile	ADJ
cusj-5649	101	5	eppendorf	eppendorf	NOUN
cusj-5649	101	6	tubes	tube	NOUN
cusj-5649	101	7	,	,	PUNCT
cusj-5649	101	8	the	the	DET
cusj-5649	101	9	appropriate	appropriate	ADJ
cusj-5649	101	10	amount	amount	NOUN
cusj-5649	101	11	of	of	ADP
cusj-5649	101	12	dna	dna	PROPN
cusj-5649	101	13	(	(	PUNCT
cusj-5649	101	14	based	base	VERB
cusj-5649	101	15	on	on	ADP
cusj-5649	101	16	absorbance	absorbance	NOUN
cusj-5649	101	17	value	value	NOUN
cusj-5649	101	18	)	)	PUNCT
cusj-5649	101	19	and	and	CCONJ
cusj-5649	101	20	20	20	NUM
cusj-5649	101	21	µl	µl	NOUN
cusj-5649	101	22	of	of	ADP
cusj-5649	101	23	lipofectamine	lipofectamine	ADJ
cusj-5649	101	24	2000	2000	NUM
cusj-5649	101	25	reagent	reagent	NOUN
cusj-5649	101	26	were	be	AUX
cusj-5649	101	27	diluted	dilute	VERB
cusj-5649	101	28	in	in	ADP
cusj-5649	101	29	50	50	NUM
cusj-5649	101	30	µl	µl	NOUN
cusj-5649	101	31	of	of	ADP
cusj-5649	101	32	serum	serum	NOUN
cusj-5649	101	33	-	-	PUNCT
cusj-5649	101	34	free	free	ADJ
cusj-5649	101	35	medium	medium	NOUN
cusj-5649	101	36	.	.	PUNCT
cusj-5649	102	1	both	both	DET
cusj-5649	102	2	tubes	tube	NOUN
cusj-5649	102	3	were	be	AUX
cusj-5649	102	4	mixed	mix	VERB
cusj-5649	102	5	gently	gently	ADV
cusj-5649	102	6	and	and	CCONJ
cusj-5649	102	7	incubated	incubate	VERB
cusj-5649	102	8	for	for	ADP
cusj-5649	102	9	5	5	NUM
cusj-5649	102	10	minutes	minute	NOUN
cusj-5649	102	11	at	at	ADP
cusj-5649	102	12	room	room	NOUN
cusj-5649	102	13	temperature	temperature	NOUN
cusj-5649	102	14	.	.	PUNCT
cusj-5649	102	15	!	!	PUNCT
cusj-5649	103	1	e	e	NOUN
cusj-5649	103	2	tubes	tube	NOUN
cusj-5649	103	3	were	be	AUX
cusj-5649	103	4	combined	combine	VERB
cusj-5649	103	5	,	,	PUNCT
cusj-5649	103	6	incubated	incubate	VERB
cusj-5649	103	7	for	for	ADP
cusj-5649	103	8	another	another	DET
cusj-5649	103	9	20	20	NUM
cusj-5649	103	10	minutes	minute	NOUN
cusj-5649	103	11	and	and	CCONJ
cusj-5649	103	12	the	the	DET
cusj-5649	103	13	entire	entire	ADJ
cusj-5649	103	14	mixture	mixture	NOUN
cusj-5649	103	15	was	be	AUX
cusj-5649	103	16	added	add	VERB
cusj-5649	103	17	to	to	ADP
cusj-5649	103	18	the	the	DET
cusj-5649	103	19	transfection	transfection	NOUN
cusj-5649	103	20	dishes	dish	NOUN
cusj-5649	103	21	.	.	PUNCT
cusj-5649	104	1	6	6	NUM
cusj-5649	104	2	hours	hour	NOUN
cusj-5649	104	3	after	after	ADP
cusj-5649	104	4	transfection	transfection	NOUN
cusj-5649	104	5	,	,	PUNCT
cusj-5649	104	6	the	the	DET
cusj-5649	104	7	media	medium	NOUN
cusj-5649	104	8	was	be	AUX
cusj-5649	104	9	changed	change	VERB
cusj-5649	104	10	to	to	ADP
cusj-5649	104	11	regular	regular	ADJ
cusj-5649	104	12	growth	growth	NOUN
cusj-5649	104	13	media	medium	NOUN
cusj-5649	104	14	(	(	PUNCT
cusj-5649	104	15	dmem	dmem	VERB
cusj-5649	104	16	+	+	CCONJ
cusj-5649	104	17	10	10	NUM
cusj-5649	104	18	%	%	NOUN
cusj-5649	104	19	fbs	fb	VERB
cusj-5649	105	1	+	+	CCONJ
cusj-5649	105	2	p	p	X
cusj-5649	105	3	/	/	SYM
cusj-5649	105	4	s	s	NOUN
cusj-5649	105	5	)	)	PUNCT
cusj-5649	105	6	.	.	PUNCT
cusj-5649	106	1	cells	cell	NOUN
cusj-5649	106	2	were	be	AUX
cusj-5649	106	3	allowed	allow	VERB
cusj-5649	106	4	to	to	PART
cusj-5649	106	5	grow	grow	VERB
cusj-5649	106	6	for	for	ADP
cusj-5649	106	7	48	48	NUM
cusj-5649	106	8	hours	hour	NOUN
cusj-5649	106	9	prior	prior	ADV
cusj-5649	106	10	to	to	ADP
cusj-5649	106	11	trans"lter	trans"lter	ADJ
cusj-5649	106	12	assays	assay	NOUN
cusj-5649	106	13	.	.	PUNCT
cusj-5649	107	1	transfilter	transfilter	NOUN
cusj-5649	107	2	migration	migration	NOUN
cusj-5649	107	3	assay	assay	VERB
cusj-5649	107	4	in	in	ADP
cusj-5649	107	5	preparation	preparation	NOUN
cusj-5649	107	6	for	for	ADP
cusj-5649	107	7	the	the	DET
cusj-5649	107	8	migration	migration	NOUN
cusj-5649	107	9	assay	assay	NOUN
cusj-5649	107	10	,	,	PUNCT
cusj-5649	107	11	the	the	DET
cusj-5649	107	12	c6	c6	PROPN
cusj-5649	107	13	cells	cell	NOUN
cusj-5649	107	14	were	be	AUX
cusj-5649	107	15	trypsinized	trypsinize	VERB
cusj-5649	107	16	from	from	ADP
cusj-5649	107	17	the	the	DET
cusj-5649	107	18	tissue	tissue	NOUN
cusj-5649	107	19	culture	culture	NOUN
cusj-5649	107	20	dishes	dish	NOUN
cusj-5649	107	21	,	,	PUNCT
cusj-5649	107	22	added	add	VERB
cusj-5649	107	23	to	to	ADP
cusj-5649	107	24	5	5	NUM
cusj-5649	107	25	ml	ml	NOUN
cusj-5649	107	26	growth	growth	NOUN
cusj-5649	107	27	medium	medium	NOUN
cusj-5649	107	28	,	,	PUNCT
cusj-5649	107	29	and	and	CCONJ
cusj-5649	107	30	spun	spin	VERB
cusj-5649	107	31	at	at	ADP
cusj-5649	107	32	1600	1600	NUM
cusj-5649	107	33	rpm	rpm	NOUN
cusj-5649	107	34	for	for	ADP
cusj-5649	107	35	5	5	NUM
cusj-5649	107	36	minutes	minute	NOUN
cusj-5649	107	37	.	.	PUNCT
cusj-5649	108	1	cells	cell	NOUN
cusj-5649	108	2	were	be	AUX
cusj-5649	108	3	resuspended	resuspend	VERB
cusj-5649	108	4	in	in	ADP
cusj-5649	108	5	1	1	NUM
cusj-5649	108	6	-	-	SYM
cusj-5649	108	7	2	2	NUM
cusj-5649	108	8	ml	ml	NOUN
cusj-5649	108	9	of	of	ADP
cusj-5649	108	10	serum	serum	NOUN
cusj-5649	108	11	-	-	PUNCT
cusj-5649	108	12	free	free	ADJ
cusj-5649	108	13	medium	medium	NOUN
cusj-5649	108	14	and	and	CCONJ
cusj-5649	108	15	kept	keep	VERB
cusj-5649	108	16	on	on	ADP
cusj-5649	108	17	ice	ice	NOUN
cusj-5649	108	18	.	.	PUNCT
cusj-5649	109	1	3	3	NUM
cusj-5649	109	2	µm	µm	NOUN
cusj-5649	109	3	pore	pore	ADJ
cusj-5649	109	4	fluoroblok	fluoroblok	NOUN
cusj-5649	109	5	trans"lters	trans"lter	NOUN
cusj-5649	109	6	(	(	PUNCT
cusj-5649	109	7	bd	bd	PROPN
cusj-5649	109	8	biosciences	bioscience	NOUN
cusj-5649	109	9	)	)	PUNCT
cusj-5649	109	10	were	be	AUX
cusj-5649	109	11	coated	coat	VERB
cusj-5649	109	12	with	with	ADP
cusj-5649	109	13	10	10	NUM
cusj-5649	109	14	%	%	NOUN
cusj-5649	109	15	type	type	NOUN
cusj-5649	109	16	1	1	NUM
cusj-5649	109	17	rat	rat	NOUN
cusj-5649	109	18	tail	tail	NOUN
cusj-5649	109	19	collagen	collagen	NOUN
cusj-5649	109	20	(	(	PUNCT
cusj-5649	109	21	bd	bd	PROPN
cusj-5649	109	22	biosciences	bioscience	NOUN
cusj-5649	109	23	)	)	PUNCT
cusj-5649	109	24	in	in	ADP
cusj-5649	109	25	sterile	sterile	ADJ
cusj-5649	109	26	de	de	ADJ
cusj-5649	109	27	-	-	ADJ
cusj-5649	109	28	ionized	ionized	ADJ
cusj-5649	109	29	water	water	NOUN
cusj-5649	109	30	at	at	ADP
cusj-5649	109	31	37	37	NUM
cusj-5649	109	32	°	°	ADP
cusj-5649	109	33	c	c	NOUN
cusj-5649	109	34	for	for	ADP
cusj-5649	109	35	1	1	NUM
cusj-5649	109	36	hour	hour	NOUN
cusj-5649	109	37	.	.	PROPN
cusj-5649	110	1	500	500	NUM
cusj-5649	110	2	µl	µl	NOUN
cusj-5649	110	3	of	of	ADP
cusj-5649	110	4	serum	serum	NOUN
cusj-5649	110	5	-	-	PUNCT
cusj-5649	110	6	containing	contain	VERB
cusj-5649	110	7	growth	growth	NOUN
cusj-5649	110	8	medium	medium	NOUN
cusj-5649	110	9	was	be	AUX
cusj-5649	110	10	added	add	VERB
cusj-5649	110	11	to	to	ADP
cusj-5649	110	12	the	the	DET
cusj-5649	110	13	bottom	bottom	NOUN
cusj-5649	110	14	of	of	ADP
cusj-5649	110	15	each	each	DET
cusj-5649	110	16	well	well	ADV
cusj-5649	110	17	beneath	beneath	ADP
cusj-5649	110	18	the	the	DET
cusj-5649	110	19	"	"	PUNCT
cusj-5649	110	20	lter	lter	NOUN
cusj-5649	110	21	to	to	PART
cusj-5649	110	22	stimulate	stimulate	VERB
cusj-5649	110	23	migration	migration	NOUN
cusj-5649	110	24	in	in	ADP
cusj-5649	110	25	a	a	DET
cusj-5649	110	26	single	single	ADJ
cusj-5649	110	27	direction	direction	NOUN
cusj-5649	110	28	(	(	PUNCT
cusj-5649	110	29	top	top	NOUN
cusj-5649	110	30	to	to	ADP
cusj-5649	110	31	bottom	bottom	NOUN
cusj-5649	110	32	)	)	PUNCT
cusj-5649	110	33	.	.	PUNCT
cusj-5649	111	1	cells	cell	NOUN
cusj-5649	111	2	were	be	AUX
cusj-5649	111	3	counted	count	VERB
cusj-5649	111	4	and	and	CCONJ
cusj-5649	111	5	the	the	DET
cusj-5649	111	6	number	number	NOUN
cusj-5649	111	7	was	be	AUX
cusj-5649	111	8	adjusted	adjust	VERB
cusj-5649	111	9	so	so	SCONJ
cusj-5649	111	10	that	that	SCONJ
cusj-5649	111	11	5x105	5x105	ADJ
cusj-5649	111	12	cells	cell	NOUN
cusj-5649	111	13	were	be	AUX
cusj-5649	111	14	added	add	VERB
cusj-5649	111	15	to	to	ADP
cusj-5649	111	16	the	the	DET
cusj-5649	111	17	top	top	NOUN
cusj-5649	111	18	of	of	ADP
cusj-5649	111	19	each	each	DET
cusj-5649	111	20	trans"lter	trans"lter	NOUN
cusj-5649	111	21	in	in	ADP
cusj-5649	111	22	a	a	DET
cusj-5649	111	23	200	200	NUM
cusj-5649	111	24	µl	µl	ADP
cusj-5649	111	25	mixture	mixture	NOUN
cusj-5649	111	26	.	.	PUNCT
cusj-5649	112	1	cells	cell	NOUN
cusj-5649	112	2	were	be	AUX
cusj-5649	112	3	left	leave	VERB
cusj-5649	112	4	in	in	ADP
cusj-5649	112	5	the	the	DET
cusj-5649	112	6	incubator	incubator	NOUN
cusj-5649	112	7	to	to	PART
cusj-5649	112	8	run	run	VERB
cusj-5649	112	9	on	on	ADP
cusj-5649	112	10	the	the	DET
cusj-5649	112	11	"	"	PUNCT
cusj-5649	112	12	lters	lter	NOUN
cusj-5649	112	13	for	for	ADP
cusj-5649	112	14	5.5	5.5	NUM
cusj-5649	112	15	hours	hour	NOUN
cusj-5649	112	16	.	.	PUNCT
cusj-5649	113	1	post	post	ADJ
cusj-5649	113	2	-	-	NOUN
cusj-5649	113	3	migration	migration	NOUN
cusj-5649	113	4	,	,	PUNCT
cusj-5649	113	5	cells	cell	NOUN
cusj-5649	113	6	were	be	AUX
cusj-5649	113	7	"	"	PUNCT
cusj-5649	113	8	xed	xe	VERB
cusj-5649	113	9	in	in	ADP
cusj-5649	113	10	4	4	NUM
cusj-5649	113	11	%	%	NOUN
cusj-5649	113	12	paraformaldeof	paraformaldeof	NOUN
cusj-5649	113	13	its	its	PRON
cusj-5649	113	14	host	host	NOUN
cusj-5649	113	15	cell	cell	NOUN
cusj-5649	113	16	4	4	NUM
cusj-5649	113	17	to	to	PART
cusj-5649	113	18	6	6	NUM
cusj-5649	113	19	hours	hour	NOUN
cusj-5649	113	20	following	follow	VERB
cusj-5649	113	21	initiation	initiation	NOUN
cusj-5649	113	22	of	of	ADP
cusj-5649	113	23	infection	infection	NOUN
cusj-5649	113	24	in	in	ADP
cusj-5649	113	25	cultured	cultured	ADJ
cusj-5649	113	26	mammalian	mammalian	ADJ
cusj-5649	113	27	cells	cell	NOUN
cusj-5649	113	28	.	.	PUNCT
cusj-5649	113	29	!	!	PUNCT
cusj-5649	114	1	e	e	NOUN
cusj-5649	114	2	mechanism	mechanism	NOUN
cusj-5649	114	3	of	of	ADP
cusj-5649	114	4	viral	viral	ADJ
cusj-5649	114	5	release	release	NOUN
cusj-5649	114	6	from	from	ADP
cusj-5649	114	7	the	the	DET
cusj-5649	114	8	cell	cell	NOUN
cusj-5649	114	9	is	be	AUX
cusj-5649	114	10	unclear	unclear	ADJ
cusj-5649	114	11	,	,	PUNCT
cusj-5649	114	12	but	but	CCONJ
cusj-5649	114	13	each	each	DET
cusj-5649	114	14	dying	die	VERB
cusj-5649	114	15	cell	cell	NOUN
cusj-5649	114	16	can	can	AUX
cusj-5649	114	17	release	release	VERB
cusj-5649	114	18	up	up	ADP
cusj-5649	114	19	to	to	PART
cusj-5649	114	20	10,000	10,000	NUM
cusj-5649	114	21	polio	polio	NOUN
cusj-5649	114	22	virions	virion	NOUN
cusj-5649	114	23	(	(	PUNCT
cusj-5649	114	24	merrill	merrill	NOUN
cusj-5649	114	25	,	,	PUNCT
cusj-5649	114	26	2004	2004	NUM
cusj-5649	114	27	)	)	PUNCT
cusj-5649	114	28	.	.	PUNCT
cusj-5649	115	1	cd155	cd155	PROPN
cusj-5649	115	2	/	/	SYM
cusj-5649	115	3	pvr	pvr	NOUN
cusj-5649	115	4	!	!	PUNCT
cusj-5649	116	1	e	e	X
cusj-5649	116	2	cellular	cellular	ADJ
cusj-5649	116	3	life	life	NOUN
cusj-5649	116	4	cycle	cycle	NOUN
cusj-5649	116	5	of	of	ADP
cusj-5649	116	6	poliovirus	poliovirus	NOUN
cusj-5649	116	7	is	be	AUX
cusj-5649	116	8	initiated	initiate	VERB
cusj-5649	116	9	by	by	ADP
cusj-5649	116	10	binding	bind	VERB
cusj-5649	116	11	to	to	ADP
cusj-5649	116	12	the	the	DET
cusj-5649	116	13	cell	cell	NOUN
cusj-5649	116	14	surface	surface	NOUN
cusj-5649	116	15	receptor	receptor	NOUN
cusj-5649	116	16	cd155	cd155	PROPN
cusj-5649	116	17	.	.	PUNCT
cusj-5649	116	18	!	!	PUNCT
cusj-5649	117	1	e	e	NOUN
cusj-5649	117	2	virion	virion	NOUN
cusj-5649	117	3	is	be	AUX
cusj-5649	117	4	taken	take	VERB
cusj-5649	117	5	up	up	ADP
cusj-5649	117	6	via	via	ADP
cusj-5649	117	7	endocytosis	endocytosis	NOUN
cusj-5649	117	8	,	,	PUNCT
cusj-5649	117	9	and	and	CCONJ
cusj-5649	117	10	the	the	DET
cusj-5649	117	11	viral	viral	ADJ
cusj-5649	117	12	rna	rna	NOUN
cusj-5649	117	13	is	be	AUX
cusj-5649	117	14	released	release	VERB
cusj-5649	117	15	.	.	PUNCT
cusj-5649	118	1	translation	translation	NOUN
cusj-5649	118	2	of	of	ADP
cusj-5649	118	3	the	the	DET
cusj-5649	118	4	viral	viral	ADJ
cusj-5649	118	5	rna	rna	NOUN
cusj-5649	118	6	occurs	occur	VERB
cusj-5649	118	7	by	by	ADP
cusj-5649	118	8	an	an	DET
cusj-5649	118	9	ires	ire	NOUN
cusj-5649	118	10	-	-	PUNCT
cusj-5649	118	11	mediated	mediate	VERB
cusj-5649	118	12	mechanism	mechanism	NOUN
cusj-5649	118	13	.	.	PUNCT
cusj-5649	118	14	!	!	PUNCT
cusj-5649	119	1	e	e	PROPN
cusj-5649	119	2	polyprotein	polyprotein	NOUN
cusj-5649	119	3	is	be	AUX
cusj-5649	119	4	then	then	ADV
cusj-5649	119	5	cleaved	cleave	VERB
cusj-5649	119	6	,	,	PUNCT
cusj-5649	119	7	yielding	yield	VERB
cusj-5649	119	8	mature	mature	ADJ
cusj-5649	119	9	viral	viral	ADJ
cusj-5649	119	10	proteins	protein	NOUN
cusj-5649	119	11	.	.	PUNCT
cusj-5649	119	12	!	!	PUNCT
cusj-5649	120	1	e	e	X
cusj-5649	120	2	positive	positive	ADJ
cusj-5649	120	3	-	-	PUNCT
cusj-5649	120	4	sense	sense	NOUN
cusj-5649	120	5	rna	rna	NOUN
cusj-5649	120	6	serves	serve	VERB
cusj-5649	120	7	as	as	ADP
cusj-5649	120	8	template	template	NOUN
cusj-5649	120	9	for	for	ADP
cusj-5649	120	10	complementary	complementary	ADJ
cusj-5649	120	11	negative	negative	ADJ
cusj-5649	120	12	-	-	PUNCT
cusj-5649	120	13	strand	strand	NOUN
cusj-5649	120	14	synthesis	synthesis	NOUN
cusj-5649	120	15	,	,	PUNCT
cusj-5649	120	16	producing	produce	VERB
cusj-5649	120	17	double	double	ADJ
cusj-5649	120	18	-	-	PUNCT
cusj-5649	120	19	stranded	strand	VERB
cusj-5649	120	20	replicative	replicative	ADJ
cusj-5649	120	21	form	form	NOUN
cusj-5649	120	22	(	(	PUNCT
cusj-5649	120	23	rf	rf	NOUN
cusj-5649	120	24	)	)	PUNCT
cusj-5649	120	25	rna	rna	NOUN
cusj-5649	120	26	.	.	PUNCT
cusj-5649	121	1	many	many	ADJ
cusj-5649	121	2	positive	positive	ADJ
cusj-5649	121	3	strand	strand	NOUN
cusj-5649	121	4	rna	rna	NOUN
cusj-5649	121	5	copies	copy	NOUN
cusj-5649	121	6	are	be	AUX
cusj-5649	121	7	produced	produce	VERB
cusj-5649	121	8	from	from	ADP
cusj-5649	121	9	the	the	DET
cusj-5649	121	10	single	single	ADJ
cusj-5649	121	11	negative	negative	ADJ
cusj-5649	121	12	strand	strand	NOUN
cusj-5649	121	13	.	.	PUNCT
cusj-5649	121	14	!	!	PUNCT
cusj-5649	122	1	e	e	X
cusj-5649	122	2	newly	newly	ADV
cusj-5649	122	3	synthesized	synthesize	VERB
cusj-5649	122	4	positivesense	positivesense	NOUN
cusj-5649	122	5	rna	rna	NOUN
cusj-5649	122	6	molecules	molecule	NOUN
cusj-5649	122	7	can	can	AUX
cusj-5649	122	8	serve	serve	VERB
cusj-5649	122	9	as	as	ADP
cusj-5649	122	10	templates	template	NOUN
cusj-5649	122	11	for	for	ADP
cusj-5649	122	12	translation	translation	NOUN
cusj-5649	122	13	of	of	ADP
cusj-5649	122	14	more	more	ADJ
cusj-5649	122	15	viral	viral	ADJ
cusj-5649	122	16	proteins	protein	NOUN
cusj-5649	122	17	,	,	PUNCT
cusj-5649	122	18	or	or	CCONJ
cusj-5649	122	19	can	can	AUX
cusj-5649	122	20	be	be	AUX
cusj-5649	122	21	enclosed	enclose	VERB
cusj-5649	122	22	in	in	ADP
cusj-5649	122	23	a	a	DET
cusj-5649	122	24	capsid	capsid	NOUN
cusj-5649	122	25	to	to	PART
cusj-5649	122	26	form	form	VERB
cusj-5649	122	27	progeny	progeny	NOUN
cusj-5649	122	28	virions	virion	NOUN
cusj-5649	122	29	.	.	PUNCT
cusj-5649	123	1	lysis	lysis	NOUN
cusj-5649	123	2	of	of	ADP
cusj-5649	123	3	the	the	DET
cusj-5649	123	4	infected	infect	VERB
cusj-5649	123	5	cell	cell	NOUN
cusj-5649	123	6	results	result	NOUN
cusj-5649	123	7	in	in	ADP
cusj-5649	123	8	release	release	NOUN
cusj-5649	123	9	of	of	ADP
cusj-5649	123	10	infectious	infectious	ADJ
cusj-5649	123	11	progeny	progeny	NOUN
cusj-5649	123	12	virions	virion	NOUN
cusj-5649	123	13	.	.	PUNCT
cusj-5649	123	14	!	!	PUNCT
cusj-5649	124	1	e	e	NOUN
cusj-5649	124	2	presence	presence	NOUN
cusj-5649	124	3	of	of	ADP
cusj-5649	124	4	cd155	cd155	PROPN
cusj-5649	124	5	is	be	AUX
cusj-5649	124	6	thought	think	VERB
cusj-5649	124	7	to	to	ADP
cusj-5649	124	8	de"ne	de"ne	PROPN
cusj-5649	124	9	the	the	DET
cusj-5649	124	10	animals	animal	NOUN
cusj-5649	124	11	that	that	PRON
cusj-5649	124	12	can	can	AUX
cusj-5649	124	13	be	be	AUX
cusj-5649	124	14	infected	infect	VERB
cusj-5649	124	15	by	by	ADP
cusj-5649	124	16	poliovirus	poliovirus	NOUN
cusj-5649	124	17	.	.	PUNCT
cusj-5649	125	1	cd155	cd155	PROPN
cusj-5649	125	2	has	have	AUX
cusj-5649	125	3	only	only	ADV
cusj-5649	125	4	been	be	AUX
cusj-5649	125	5	thought	think	VERB
cusj-5649	125	6	to	to	PART
cusj-5649	125	7	be	be	AUX
cusj-5649	125	8	on	on	ADP
cusj-5649	125	9	the	the	DET
cusj-5649	125	10	cells	cell	NOUN
cusj-5649	125	11	of	of	ADP
cusj-5649	125	12	humans	human	NOUN
cusj-5649	125	13	,	,	PUNCT
cusj-5649	125	14	higher	high	ADJ
cusj-5649	125	15	primates	primate	NOUN
cusj-5649	125	16	,	,	PUNCT
cusj-5649	125	17	and	and	CCONJ
cusj-5649	125	18	old	old	ADJ
cusj-5649	125	19	world	world	NOUN
cusj-5649	125	20	monkeys	monkey	NOUN
cusj-5649	125	21	.	.	PUNCT
cusj-5649	126	1	poliovirus	poliovirus	NOUN
cusj-5649	126	2	is	be	AUX
cusj-5649	126	3	however	however	ADV
cusj-5649	126	4	strictly	strictly	ADV
cusj-5649	126	5	a	a	DET
cusj-5649	126	6	human	human	ADJ
cusj-5649	126	7	pathogen	pathogen	NOUN
cusj-5649	126	8	,	,	PUNCT
cusj-5649	126	9	and	and	CCONJ
cusj-5649	126	10	does	do	AUX
cusj-5649	126	11	not	not	PART
cusj-5649	126	12	naturally	naturally	ADV
cusj-5649	126	13	infect	infect	VERB
cusj-5649	126	14	any	any	DET
cusj-5649	126	15	other	other	ADJ
cusj-5649	126	16	species	specie	NOUN
cusj-5649	126	17	.	.	PUNCT
cusj-5649	127	1	cd155	cd155	PROPN
cusj-5649	127	2	is	be	AUX
cusj-5649	127	3	a	a	DET
cusj-5649	127	4	type	type	NOUN
cusj-5649	127	5	i	i	PRON
cusj-5649	127	6	transmembrane	transmembrane	ADJ
cusj-5649	127	7	glycoprotein	glycoprotein	NOUN
cusj-5649	127	8	in	in	ADP
cusj-5649	127	9	the	the	DET
cusj-5649	127	10	immunoglobulin	immunoglobulin	NOUN
cusj-5649	127	11	superfamily	superfamily	NOUN
cusj-5649	127	12	.	.	PUNCT
cusj-5649	128	1	commonly	commonly	ADV
cusj-5649	128	2	known	know	VERB
cusj-5649	128	3	as	as	ADP
cusj-5649	128	4	poliovirus	poliovirus	NOUN
cusj-5649	128	5	receptor	receptor	NOUN
cusj-5649	128	6	(	(	PUNCT
cusj-5649	128	7	pvr	pvr	NOUN
cusj-5649	128	8	)	)	PUNCT
cusj-5649	128	9	due	due	ADP
cusj-5649	128	10	to	to	ADP
cusj-5649	128	11	its	its	PRON
cusj-5649	128	12	involvement	involvement	NOUN
cusj-5649	128	13	in	in	ADP
cusj-5649	128	14	the	the	DET
cusj-5649	128	15	cellular	cellular	ADJ
cusj-5649	128	16	poliovirus	poliovirus	NOUN
cusj-5649	128	17	infection	infection	NOUN
cusj-5649	128	18	in	in	ADP
cusj-5649	128	19	primates	primate	NOUN
cusj-5649	128	20	,	,	PUNCT
cusj-5649	128	21	cd155	cd155	PROPN
cusj-5649	128	22	’s	’s	PART
cusj-5649	128	23	normal	normal	ADJ
cusj-5649	128	24	cellular	cellular	ADJ
cusj-5649	128	25	function	function	NOUN
cusj-5649	128	26	is	be	AUX
cusj-5649	128	27	in	in	ADP
cusj-5649	128	28	the	the	DET
cusj-5649	128	29	establishment	establishment	NOUN
cusj-5649	128	30	of	of	ADP
cusj-5649	128	31	intercellular	intercellular	ADJ
cusj-5649	128	32	adherens	adheren	NOUN
cusj-5649	128	33	junctions	junction	NOUN
cusj-5649	128	34	between	between	ADP
cusj-5649	128	35	epithelial	epithelial	ADJ
cusj-5649	128	36	cells	cell	NOUN
cusj-5649	128	37	.	.	PUNCT
cusj-5649	129	1	like	like	ADP
cusj-5649	129	2	many	many	ADJ
cusj-5649	129	3	other	other	ADJ
cusj-5649	129	4	receptor	receptor	NOUN
cusj-5649	129	5	molecules	molecule	NOUN
cusj-5649	129	6	used	use	VERB
cusj-5649	129	7	by	by	ADP
cusj-5649	129	8	picornaviruses	picornavirus	NOUN
cusj-5649	129	9	,	,	PUNCT
cusj-5649	129	10	cd155	cd155	PROPN
cusj-5649	129	11	is	be	AUX
cusj-5649	129	12	a	a	DET
cusj-5649	129	13	long	long	ADJ
cusj-5649	129	14	,	,	PUNCT
cusj-5649	129	15	highly	highly	ADV
cusj-5649	129	16	glycosylated	glycosylated	ADJ
cusj-5649	129	17	,	,	PUNCT
cusj-5649	129	18	single	single	ADJ
cusj-5649	129	19	-	-	PUNCT
cusj-5649	129	20	span	span	NOUN
cusj-5649	129	21	surface	surface	NOUN
cusj-5649	129	22	molecule	molecule	NOUN
cusj-5649	129	23	.	.	PUNCT
cusj-5649	130	1	while	while	SCONJ
cusj-5649	130	2	its	its	PRON
cusj-5649	130	3	predominant	predominant	ADJ
cusj-5649	130	4	function	function	NOUN
cusj-5649	130	5	is	be	AUX
cusj-5649	130	6	related	relate	VERB
cusj-5649	130	7	to	to	ADP
cusj-5649	130	8	cellular	cellular	ADJ
cusj-5649	130	9	adhesion	adhesion	NOUN
cusj-5649	130	10	and	and	CCONJ
cusj-5649	130	11	activation	activation	NOUN
cusj-5649	130	12	,	,	PUNCT
cusj-5649	130	13	cd155	cd155	PROPN
cusj-5649	130	14	also	also	ADV
cusj-5649	130	15	activates	activate	VERB
cusj-5649	130	16	natural	natural	ADJ
cusj-5649	130	17	killer	killer	NOUN
cusj-5649	130	18	cells	cell	NOUN
cusj-5649	130	19	and	and	CCONJ
cusj-5649	130	20	has	have	AUX
cusj-5649	130	21	been	be	AUX
cusj-5649	130	22	reported	report	VERB
cusj-5649	130	23	to	to	PART
cusj-5649	130	24	play	play	VERB
cusj-5649	130	25	a	a	DET
cusj-5649	130	26	role	role	NOUN
cusj-5649	130	27	in	in	ADP
cusj-5649	130	28	cell	cell	NOUN
cusj-5649	130	29	motility	motility	NOUN
cusj-5649	130	30	and	and	CCONJ
cusj-5649	130	31	tumor	tumor	NOUN
cusj-5649	130	32	cell	cell	NOUN
cusj-5649	130	33	invasion	invasion	NOUN
cusj-5649	130	34	.	.	PUNCT
cusj-5649	131	1	it	it	PRON
cusj-5649	131	2	consists	consist	VERB
cusj-5649	131	3	of	of	ADP
cusj-5649	131	4	3	3	NUM
cusj-5649	131	5	successive	successive	ADJ
cusj-5649	131	6	ig	ig	PROPN
cusj-5649	131	7	-	-	PUNCT
cusj-5649	131	8	like	like	ADJ
cusj-5649	131	9	domains	domain	NOUN
cusj-5649	131	10	(	(	PUNCT
cusj-5649	131	11	d1	d1	NOUN
cusj-5649	131	12	,	,	PUNCT
cusj-5649	131	13	d2	d2	PROPN
cusj-5649	131	14	,	,	PUNCT
cusj-5649	131	15	and	and	CCONJ
cusj-5649	131	16	d3	d3	PROPN
cusj-5649	131	17	)	)	PUNCT
cusj-5649	131	18	,	,	PUNCT
cusj-5649	131	19	a	a	DET
cusj-5649	131	20	transmembrane	transmembrane	ADJ
cusj-5649	131	21	domain	domain	NOUN
cusj-5649	131	22	and	and	CCONJ
cusj-5649	131	23	a	a	DET
cusj-5649	131	24	cterminal	cterminal	ADJ
cusj-5649	131	25	cytoplasmic	cytoplasmic	ADJ
cusj-5649	131	26	domain	domain	NOUN
cusj-5649	131	27	.	.	PUNCT
cusj-5649	131	28	!	!	PUNCT
cusj-5649	132	1	e	e	PROPN
cusj-5649	132	2	human	human	PROPN
cusj-5649	132	3	cd155	cd155	PROPN
cusj-5649	132	4	gene	gene	NOUN
cusj-5649	132	5	is	be	AUX
cusj-5649	132	6	expressed	express	VERB
cusj-5649	132	7	in	in	ADP
cusj-5649	132	8	4	4	NUM
cusj-5649	132	9	splice	splice	NOUN
cusj-5649	132	10	variants	variant	NOUN
cusj-5649	132	11	(	(	PUNCT
cusj-5649	132	12	ơ	ơ	PROPN
cusj-5649	132	13	,	,	PUNCT
cusj-5649	132	14	ơ	ơ	PROPN
cusj-5649	132	15	,	,	PUNCT
cusj-5649	132	16	ƣ	ƣ	X
cusj-5649	132	17	,	,	PUNCT
cusj-5649	132	18	and	and	CCONJ
cusj-5649	132	19	ǆ	ǆ	X
cusj-5649	132	20	)	)	PUNCT
cusj-5649	132	21	of	of	ADP
cusj-5649	132	22	which	which	PRON
cusj-5649	132	23	2	2	NUM
cusj-5649	132	24	variants	variant	NOUN
cusj-5649	132	25	(	(	PUNCT
cusj-5649	132	26	ơ	ơ	PROPN
cusj-5649	132	27	and	and	CCONJ
cusj-5649	132	28	ƣ	ƣ	X
cusj-5649	132	29	)	)	PUNCT
cusj-5649	132	30	are	be	AUX
cusj-5649	132	31	lacking	lack	VERB
cusj-5649	132	32	the	the	DET
cusj-5649	132	33	transmembrane	transmembrane	ADJ
cusj-5649	132	34	domain	domain	NOUN
cusj-5649	132	35	and	and	CCONJ
cusj-5649	132	36	are	be	AUX
cusj-5649	132	37	released	release	VERB
cusj-5649	132	38	from	from	ADP
cusj-5649	132	39	the	the	DET
cusj-5649	132	40	cell	cell	NOUN
cusj-5649	132	41	subsequent	subsequent	ADJ
cusj-5649	132	42	to	to	ADP
cusj-5649	132	43	their	their	PRON
cusj-5649	132	44	expression	expression	NOUN
cusj-5649	132	45	.	.	PUNCT
cusj-5649	132	46	!	!	PUNCT
cusj-5649	133	1	e	e	X
cusj-5649	133	2	cd155ơ	cd155ơ	PROPN
cusj-5649	133	3	and	and	CCONJ
cusj-5649	133	4	cd155ǆ	cd155ǆ	PROPN
cusj-5649	133	5	isotypes	isotype	NOUN
cusj-5649	133	6	di#er	di#er	PRON
cusj-5649	133	7	only	only	ADV
cusj-5649	133	8	in	in	ADP
cusj-5649	133	9	their	their	PRON
cusj-5649	133	10	cytoplasmic	cytoplasmic	ADJ
cusj-5649	133	11	domains	domain	NOUN
cusj-5649	133	12	and	and	CCONJ
cusj-5649	133	13	can	can	AUX
cusj-5649	133	14	both	both	PRON
cusj-5649	133	15	function	function	VERB
cusj-5649	133	16	as	as	ADP
cusj-5649	133	17	pv	pv	NOUN
cusj-5649	133	18	receptors	receptor	NOUN
cusj-5649	133	19	zhang	zhang	PROPN
cusj-5649	133	20	,	,	PUNCT
cusj-5649	133	21	2008	2008	NUM
cusj-5649	133	22	)	)	PUNCT
cusj-5649	133	23	.	.	PUNCT
cusj-5649	134	1	cd155	cd155	NOUN
cusj-5649	134	2	protein	protein	NOUN
cusj-5649	134	3	binds	bind	VERB
cusj-5649	134	4	speci"cally	speci"cally	ADV
cusj-5649	134	5	to	to	ADP
cusj-5649	134	6	the	the	DET
cusj-5649	134	7	extracellular	extracellular	ADJ
cusj-5649	134	8	matrix	matrix	NOUN
cusj-5649	134	9	component	component	NOUN
cusj-5649	134	10	vitronectin	vitronectin	NOUN
cusj-5649	134	11	.	.	PUNCT
cusj-5649	135	1	con"rming	con"rme	VERB
cusj-5649	135	2	the	the	DET
cusj-5649	135	3	activity	activity	NOUN
cusj-5649	135	4	pattern	pattern	NOUN
cusj-5649	135	5	of	of	ADP
cusj-5649	135	6	the	the	DET
cusj-5649	135	7	cd155	cd155	NOUN
cusj-5649	135	8	promoter	promoter	NOUN
cusj-5649	135	9	in	in	ADP
cusj-5649	135	10	the	the	DET
cusj-5649	135	11	developing	develop	VERB
cusj-5649	135	12	spinal	spinal	ADJ
cusj-5649	135	13	cord	cord	NOUN
cusj-5649	135	14	,	,	PUNCT
cusj-5649	135	15	morphogenic	morphogenic	ADJ
cusj-5649	135	16	factors	factor	NOUN
cusj-5649	135	17	active	active	ADJ
cusj-5649	135	18	in	in	ADP
cusj-5649	135	19	the	the	DET
cusj-5649	135	20	$	$	SYM
cusj-5649	135	21	oor	oor	NOUN
cusj-5649	135	22	plate	plate	NOUN
cusj-5649	135	23	and	and	CCONJ
cusj-5649	135	24	notochord	notochord	NOUN
cusj-5649	135	25	—	—	PUNCT
cusj-5649	135	26	the	the	DET
cusj-5649	135	27	transcription	transcription	NOUN
cusj-5649	135	28	factors	factor	VERB
cusj-5649	135	29	sonic	sonic	ADJ
cusj-5649	135	30	hedgehog	hedgehog	PROPN
cusj-5649	135	31	(	(	PUNCT
cusj-5649	135	32	shh	shh	NOUN
cusj-5649	135	33	)	)	PUNCT
cusj-5649	135	34	and	and	CCONJ
cusj-5649	135	35	its	its	PRON
cusj-5649	135	36	downstream	downstream	ADJ
cusj-5649	135	37	gli	gli	NOUN
cusj-5649	135	38	e#ectors	e#ector	NOUN
cusj-5649	135	39	—	—	PUNCT
cusj-5649	135	40	strongly	strongly	ADV
cusj-5649	135	41	activate	activate	VERB
cusj-5649	135	42	the	the	DET
cusj-5649	135	43	cd155	cd155	NOUN
cusj-5649	135	44	promoter	promoter	NOUN
cusj-5649	135	45	and	and	CCONJ
cusj-5649	135	46	induce	induce	VERB
cusj-5649	135	47	cd155	cd155	NOUN
cusj-5649	135	48	expression	expression	NOUN
cusj-5649	135	49	.	.	PUNCT
cusj-5649	136	1	both	both	PRON
cusj-5649	136	2	shh	shh	NOUN
cusj-5649	136	3	and	and	CCONJ
cusj-5649	136	4	gli	gli	NOUN
cusj-5649	136	5	transcription	transcription	NOUN
cusj-5649	136	6	factors	factor	NOUN
cusj-5649	136	7	have	have	AUX
cusj-5649	136	8	been	be	AUX
cusj-5649	136	9	implicated	implicate	VERB
cusj-5649	136	10	in	in	ADP
cusj-5649	136	11	the	the	DET
cusj-5649	136	12	oncogenesis	oncogenesis	NOUN
cusj-5649	136	13	of	of	ADP
cusj-5649	136	14	neuroectodermal	neuroectodermal	ADJ
cusj-5649	136	15	tumors	tumor	NOUN
cusj-5649	136	16	.	.	PUNCT
cusj-5649	136	17	!	!	PUNCT
cusj-5649	137	1	us	we	PRON
cusj-5649	137	2	,	,	PUNCT
cusj-5649	137	3	the	the	DET
cusj-5649	137	4	role	role	NOUN
cusj-5649	137	5	of	of	ADP
cusj-5649	137	6	shh	shh	NOUN
cusj-5649	137	7	and	and	CCONJ
cusj-5649	137	8	gli	gli	NOUN
cusj-5649	137	9	transcription	transcription	NOUN
cusj-5649	137	10	factors	factor	NOUN
cusj-5649	137	11	in	in	ADP
cusj-5649	137	12	cd155	cd155	NOUN
cusj-5649	137	13	gene	gene	NOUN
cusj-5649	137	14	regulation	regulation	NOUN
cusj-5649	137	15	suggested	suggest	VERB
cusj-5649	137	16	that	that	SCONJ
cusj-5649	137	17	cd155	cd155	NOUN
cusj-5649	137	18	expression	expression	NOUN
cusj-5649	137	19	may	may	AUX
cusj-5649	137	20	occur	occur	VERB
cusj-5649	137	21	ectopically	ectopically	ADV
cusj-5649	137	22	in	in	ADP
cusj-5649	137	23	neuroectodermal	neuroectodermal	ADJ
cusj-5649	137	24	malignancies	malignancy	NOUN
cusj-5649	137	25	.	.	PUNCT
cusj-5649	138	1	evidence	evidence	NOUN
cusj-5649	138	2	for	for	ADP
cusj-5649	138	3	cd155	cd155	NOUN
cusj-5649	138	4	expression	expression	NOUN
cusj-5649	138	5	in	in	ADP
cusj-5649	138	6	neuroectodermal	neuroectodermal	ADJ
cusj-5649	138	7	tumors	tumor	NOUN
cusj-5649	138	8	stems	stem	VERB
cusj-5649	138	9	mainly	mainly	ADV
cusj-5649	138	10	from	from	ADP
cusj-5649	138	11	studies	study	NOUN
cusj-5649	138	12	of	of	ADP
cusj-5649	138	13	neuroectodermal	neuroectodermal	ADJ
cusj-5649	138	14	tumor	tumor	NOUN
cusj-5649	138	15	cell	cell	NOUN
cusj-5649	138	16	lines	line	NOUN
cusj-5649	138	17	that	that	PRON
cusj-5649	138	18	are	be	AUX
cusj-5649	138	19	susceptible	susceptible	ADJ
cusj-5649	138	20	to	to	ADP
cusj-5649	138	21	oncolytic	oncolytic	ADJ
cusj-5649	138	22	poliovirus	poliovirus	NOUN
cusj-5649	138	23	-	-	PUNCT
cusj-5649	138	24	based	base	VERB
cusj-5649	138	25	agents	agent	NOUN
cusj-5649	138	26	(	(	PUNCT
cusj-5649	138	27	solecki	solecki	PROPN
cusj-5649	138	28	,	,	PUNCT
cusj-5649	138	29	2002	2002	NUM
cusj-5649	138	30	)	)	PUNCT
cusj-5649	138	31	.	.	PUNCT
cusj-5649	139	1	oncolytic	oncolytic	ADJ
cusj-5649	139	2	applications	application	NOUN
cusj-5649	139	3	viral	viral	ADJ
cusj-5649	139	4	oncolysis	oncolysis	NOUN
cusj-5649	139	5	has	have	AUX
cusj-5649	139	6	been	be	AUX
cusj-5649	139	7	recently	recently	ADV
cusj-5649	139	8	recognized	recognize	VERB
cusj-5649	139	9	as	as	ADP
cusj-5649	139	10	a	a	DET
cusj-5649	139	11	new	new	ADJ
cusj-5649	139	12	development	development	NOUN
cusj-5649	139	13	in	in	ADP
cusj-5649	139	14	the	the	DET
cusj-5649	139	15	treatment	treatment	NOUN
cusj-5649	139	16	of	of	ADP
cusj-5649	139	17	malignant	malignant	ADJ
cusj-5649	139	18	glioma	glioma	NOUN
cusj-5649	139	19	.	.	PUNCT
cusj-5649	140	1	oncolytic	oncolytic	ADJ
cusj-5649	140	2	viruses	virus	NOUN
cusj-5649	140	3	must	must	AUX
cusj-5649	140	4	speci"cally	speci"cally	ADV
cusj-5649	140	5	target	target	VERB
cusj-5649	140	6	tumor	tumor	NOUN
cusj-5649	140	7	cells	cell	NOUN
cusj-5649	140	8	,	,	PUNCT
cusj-5649	140	9	a	a	DET
cusj-5649	140	10	property	property	NOUN
cusj-5649	140	11	related	relate	VERB
cusj-5649	140	12	to	to	ADP
cusj-5649	140	13	the	the	DET
cusj-5649	140	14	fact	fact	NOUN
cusj-5649	140	15	that	that	SCONJ
cusj-5649	140	16	tumor	tumor	NOUN
cusj-5649	140	17	cells	cell	NOUN
cusj-5649	140	18	often	often	ADV
cusj-5649	140	19	have	have	AUX
cusj-5649	140	20	aberrant	aberrant	ADJ
cusj-5649	140	21	innate	innate	ADJ
cusj-5649	140	22	immune	immune	ADJ
cusj-5649	140	23	reponses	reponse	NOUN
cusj-5649	140	24	.	.	PUNCT
cusj-5649	140	25	!	!	PUNCT
cusj-5649	141	1	e	e	X
cusj-5649	141	2	"	"	PUNCT
cusj-5649	141	3	rst	rst	PROPN
cusj-5649	141	4	reported	report	VERB
cusj-5649	141	5	incidences	incidence	NOUN
cusj-5649	141	6	of	of	ADP
cusj-5649	141	7	viral	viral	ADJ
cusj-5649	141	8	oncolysis	oncolysis	NOUN
cusj-5649	141	9	,	,	PUNCT
cusj-5649	141	10	over	over	ADP
cusj-5649	141	11	a	a	DET
cusj-5649	141	12	century	century	NOUN
cusj-5649	141	13	ago	ago	ADV
cusj-5649	141	14	,	,	PUNCT
cusj-5649	141	15	were	be	AUX
cusj-5649	141	16	due	due	ADJ
cusj-5649	141	17	to	to	ADP
cusj-5649	141	18	nonintended	nonintende	VERB
cusj-5649	141	19	exposure	exposure	NOUN
cusj-5649	141	20	to	to	ADP
cusj-5649	141	21	naturally	naturally	ADV
cusj-5649	141	22	occurring	occur	VERB
cusj-5649	141	23	viruses	virus	NOUN
cusj-5649	141	24	or	or	CCONJ
cusj-5649	141	25	after	after	SCONJ
cusj-5649	141	26	administration	administration	NOUN
cusj-5649	141	27	of	of	ADP
cusj-5649	141	28	live	live	ADJ
cusj-5649	141	29	attenuated	attenuated	ADJ
cusj-5649	141	30	vaccine	vaccine	NOUN
cusj-5649	141	31	strains	strain	VERB
cusj-5649	141	32	.	.	PUNCT
cusj-5649	142	1	in	in	ADP
cusj-5649	142	2	the	the	DET
cusj-5649	142	3	last	last	ADJ
cusj-5649	142	4	twenty	twenty	NUM
cusj-5649	142	5	years	year	NOUN
cusj-5649	142	6	,	,	PUNCT
cusj-5649	142	7	new	new	ADJ
cusj-5649	142	8	prospects	prospect	NOUN
cusj-5649	142	9	for	for	ADP
cusj-5649	142	10	genetically	genetically	ADV
cusj-5649	142	11	manipulating	manipulate	VERB
cusj-5649	142	12	viruses	virus	NOUN
cusj-5649	142	13	have	have	AUX
cusj-5649	142	14	opened	open	VERB
cusj-5649	142	15	possibilities	possibility	NOUN
cusj-5649	142	16	for	for	ADP
cusj-5649	142	17	increasing	increase	VERB
cusj-5649	142	18	the	the	DET
cusj-5649	142	19	tumor	tumor	NOUN
cusj-5649	142	20	speci"city	speci"city	NOUN
cusj-5649	142	21	and	and	CCONJ
cusj-5649	142	22	lowering	lower	VERB
cusj-5649	142	23	the	the	DET
cusj-5649	142	24	toxicity	toxicity	NOUN
cusj-5649	142	25	of	of	ADP
cusj-5649	142	26	oncolytic	oncolytic	ADJ
cusj-5649	142	27	viral	viral	ADJ
cusj-5649	142	28	agents	agent	NOUN
cusj-5649	142	29	.	.	PUNCT
cusj-5649	142	30	!	!	PUNCT
cusj-5649	143	1	ese	ese	PROPN
cusj-5649	143	2	e#orts	e#orts	PROPN
cusj-5649	143	3	have	have	AUX
cusj-5649	143	4	given	give	VERB
cusj-5649	143	5	rise	rise	NOUN
cusj-5649	143	6	to	to	ADP
cusj-5649	143	7	oncolytic	oncolytic	ADJ
cusj-5649	143	8	adenoviruses	adenovirus	NOUN
cusj-5649	143	9	,	,	PUNCT
cusj-5649	143	10	herpesviruses	herpesviruse	NOUN
cusj-5649	143	11	,	,	PUNCT
cusj-5649	143	12	reoviruses	reovirus	NOUN
cusj-5649	143	13	,	,	PUNCT
cusj-5649	143	14	vesicular	vesicular	ADJ
cusj-5649	143	15	stomatitis	stomatitis	NOUN
cusj-5649	143	16	virus	virus	NOUN
cusj-5649	143	17	,	,	PUNCT
cusj-5649	143	18	and	and	CCONJ
cusj-5649	143	19	most	most	ADV
cusj-5649	143	20	recently	recently	ADV
cusj-5649	143	21	,	,	PUNCT
cusj-5649	143	22	polioviruses	poliovirus	NOUN
cusj-5649	143	23	.	.	PUNCT
cusj-5649	143	24	!	!	PUNCT
cusj-5649	144	1	e	e	PROPN
cusj-5649	144	2	antineoplastic	antineoplastic	ADJ
cusj-5649	144	3	e#ects	e#ect	NOUN
cusj-5649	144	4	of	of	ADP
cusj-5649	144	5	oncolytic	oncolytic	ADJ
cusj-5649	144	6	viruses	virus	NOUN
cusj-5649	144	7	are	be	AUX
cusj-5649	144	8	subject	subject	ADJ
cusj-5649	144	9	to	to	ADP
cusj-5649	144	10	multifaceted	multifaceted	ADJ
cusj-5649	144	11	interactions	interaction	NOUN
cusj-5649	144	12	with	with	ADP
cusj-5649	144	13	the	the	DET
cusj-5649	144	14	host	host	NOUN
cusj-5649	144	15	cell	cell	NOUN
cusj-5649	144	16	.	.	PUNCT
cusj-5649	144	17	!	!	PUNCT
cusj-5649	145	1	e	e	PROPN
cusj-5649	145	2	primary	primary	ADJ
cusj-5649	145	3	prerequisite	prerequisite	NOUN
cusj-5649	145	4	for	for	ADP
cusj-5649	145	5	viral	viral	ADJ
cusj-5649	145	6	oncolysis	oncolysis	NOUN
cusj-5649	145	7	is	be	AUX
cusj-5649	145	8	expression	expression	NOUN
cusj-5649	145	9	of	of	ADP
cusj-5649	145	10	cellular	cellular	ADJ
cusj-5649	145	11	receptors	receptor	NOUN
cusj-5649	145	12	mediating	mediate	VERB
cusj-5649	145	13	viral	viral	ADJ
cusj-5649	145	14	entry	entry	NOUN
cusj-5649	145	15	in	in	ADP
cusj-5649	145	16	malignant	malignant	ADJ
cusj-5649	145	17	cell	cell	NOUN
cusj-5649	145	18	types	type	NOUN
cusj-5649	145	19	.	.	PUNCT
cusj-5649	146	1	in	in	ADP
cusj-5649	146	2	preparation	preparation	NOUN
cusj-5649	146	3	for	for	ADP
cusj-5649	146	4	clinical	clinical	ADJ
cusj-5649	146	5	applications	application	NOUN
cusj-5649	146	6	using	use	VERB
cusj-5649	146	7	oncolytic	oncolytic	ADJ
cusj-5649	146	8	viruses	virus	NOUN
cusj-5649	146	9	,	,	PUNCT
cusj-5649	146	10	analysis	analysis	NOUN
cusj-5649	146	11	of	of	ADP
cusj-5649	146	12	viral	viral	ADJ
cusj-5649	146	13	receptor	receptor	NOUN
cusj-5649	146	14	expression	expression	NOUN
cusj-5649	146	15	in	in	ADP
cusj-5649	146	16	the	the	DET
cusj-5649	146	17	target	target	NOUN
cusj-5649	146	18	tissue	tissue	NOUN
cusj-5649	146	19	is	be	AUX
cusj-5649	146	20	highly	highly	ADV
cusj-5649	146	21	desirable	desirable	ADJ
cusj-5649	146	22	in	in	ADP
cusj-5649	146	23	order	order	NOUN
cusj-5649	146	24	to	to	PART
cusj-5649	146	25	select	select	VERB
cusj-5649	146	26	tumor	tumor	NOUN
cusj-5649	146	27	types	type	NOUN
cusj-5649	146	28	and	and	CCONJ
cusj-5649	146	29	patients	patient	NOUN
cusj-5649	146	30	most	most	ADV
cusj-5649	146	31	likely	likely	ADJ
cusj-5649	146	32	to	to	PART
cusj-5649	146	33	respond	respond	VERB
cusj-5649	146	34	favorably	favorably	ADV
cusj-5649	146	35	to	to	ADP
cusj-5649	146	36	therapeutic	therapeutic	ADJ
cusj-5649	146	37	intervention	intervention	NOUN
cusj-5649	146	38	.	.	PUNCT
cusj-5649	147	1	cell	cell	NOUN
cusj-5649	147	2	adhesion	adhesion	NOUN
cusj-5649	147	3	molecules	molecule	NOUN
cusj-5649	147	4	of	of	ADP
cusj-5649	147	5	the	the	DET
cusj-5649	147	6	immunoglobulin	immunoglobulin	NOUN
cusj-5649	147	7	superfamily	superfamily	ADV
cusj-5649	147	8	are	be	AUX
cusj-5649	147	9	aberrantly	aberrantly	ADV
cusj-5649	147	10	expressed	express	VERB
cusj-5649	147	11	in	in	ADP
cusj-5649	147	12	malignant	malignant	ADJ
cusj-5649	147	13	glioma	glioma	NOUN
cusj-5649	147	14	.	.	PUNCT
cusj-5649	148	1	amongst	amongst	ADP
cusj-5649	148	2	these	these	PRON
cusj-5649	148	3	,	,	PUNCT
cusj-5649	148	4	the	the	DET
cusj-5649	148	5	human	human	ADJ
cusj-5649	148	6	poliovirus	poliovirus	NOUN
cusj-5649	148	7	receptor	receptor	NOUN
cusj-5649	148	8	cd155	cd155	PROPN
cusj-5649	148	9	provides	provide	VERB
cusj-5649	148	10	a	a	DET
cusj-5649	148	11	molecular	molecular	ADJ
cusj-5649	148	12	target	target	NOUN
cusj-5649	148	13	for	for	ADP
cusj-5649	148	14	therapeutic	therapeutic	ADJ
cusj-5649	148	15	intervention	intervention	NOUN
cusj-5649	148	16	with	with	ADP
cusj-5649	148	17	oncolytic	oncolytic	ADJ
cusj-5649	148	18	poliovirus	poliovirus	NOUN
cusj-5649	148	19	recombinants	recombinant	NOUN
cusj-5649	148	20	.	.	PUNCT
cusj-5649	149	1	analysis	analysis	NOUN
cusj-5649	149	2	of	of	ADP
cusj-5649	149	3	6	6	NUM
cusj-5649	149	4	cases	case	NOUN
cusj-5649	149	5	has	have	AUX
cusj-5649	149	6	indicated	indicate	VERB
cusj-5649	149	7	that	that	SCONJ
cusj-5649	149	8	cd155	cd155	NOUN
cusj-5649	149	9	over	over	ADP
cusj-5649	149	10	-	-	PUNCT
cusj-5649	149	11	expression	expression	NOUN
cusj-5649	149	12	is	be	AUX
cusj-5649	149	13	commonly	commonly	ADV
cusj-5649	149	14	associated	associate	VERB
cusj-5649	149	15	with	with	ADP
cusj-5649	149	16	high	high	ADJ
cusj-5649	149	17	-	-	PUNCT
cusj-5649	149	18	grade	grade	NOUN
cusj-5649	149	19	malignant	malignant	ADJ
cusj-5649	149	20	glioma	glioma	NOUN
cusj-5649	149	21	(	(	PUNCT
cusj-5649	149	22	hgl	hgl	NOUN
cusj-5649	149	23	)	)	PUNCT
cusj-5649	149	24	.	.	PUNCT
cusj-5649	150	1	cd155	cd155	NOUN
cusj-5649	150	2	expression	expression	NOUN
cusj-5649	150	3	levels	level	NOUN
cusj-5649	150	4	in	in	ADP
cusj-5649	150	5	tumor	tumor	NOUN
cusj-5649	150	6	tissues	tissue	NOUN
cusj-5649	150	7	corresponded	correspond	VERB
cusj-5649	150	8	to	to	ADP
cusj-5649	150	9	those	those	PRON
cusj-5649	150	10	in	in	ADP
cusj-5649	150	11	primary	primary	ADJ
cusj-5649	150	12	tissue	tissue	NOUN
cusj-5649	150	13	cultures	culture	NOUN
cusj-5649	150	14	derived	derive	VERB
cusj-5649	150	15	from	from	ADP
cusj-5649	150	16	the	the	DET
cusj-5649	150	17	tumors	tumor	NOUN
cusj-5649	150	18	.	.	PUNCT
cusj-5649	151	1	furthermore	furthermore	ADV
cusj-5649	151	2	,	,	PUNCT
cusj-5649	151	3	cd155	cd155	NOUN
cusj-5649	151	4	expression	expression	NOUN
cusj-5649	151	5	in	in	ADP
cusj-5649	151	6	primary	primary	ADJ
cusj-5649	151	7	glioma	glioma	NOUN
cusj-5649	151	8	explant	explant	NOUN
cusj-5649	151	9	cultures	culture	NOUN
cusj-5649	151	10	was	be	AUX
cusj-5649	151	11	equivalent	equivalent	ADJ
cusj-5649	151	12	to	to	ADP
cusj-5649	151	13	that	that	PRON
cusj-5649	151	14	found	find	VERB
cusj-5649	151	15	in	in	ADP
cusj-5649	151	16	established	establish	VERB
cusj-5649	151	17	glioma	glioma	NOUN
cusj-5649	151	18	cell	cell	NOUN
cusj-5649	151	19	lines	line	NOUN
cusj-5649	151	20	used	use	VERB
cusj-5649	151	21	in	in	ADP
cusj-5649	151	22	preclinical	preclinical	ADJ
cusj-5649	151	23	evaluations	evaluation	NOUN
cusj-5649	151	24	of	of	ADP
cusj-5649	151	25	oncolytic	oncolytic	ADJ
cusj-5649	151	26	poliovirus	poliovirus	NOUN
cusj-5649	151	27	recombinants	recombinant	NOUN
cusj-5649	151	28	.	.	PUNCT
cusj-5649	152	1	poliovirus	poliovirus	NOUN
cusj-5649	152	2	has	have	AUX
cusj-5649	152	3	been	be	AUX
cusj-5649	152	4	genetically	genetically	ADV
cusj-5649	152	5	modi"ed	modi"e	VERB
cusj-5649	152	6	through	through	ADP
cusj-5649	152	7	insertion	insertion	NOUN
cusj-5649	152	8	of	of	ADP
cusj-5649	152	9	regulatory	regulatory	ADJ
cusj-5649	152	10	sequences	sequence	NOUN
cusj-5649	152	11	derived	derive	VERB
cusj-5649	152	12	from	from	ADP
cusj-5649	152	13	human	human	ADJ
cusj-5649	152	14	rhinovirus	rhinovirus	NOUN
cusj-5649	152	15	type	type	NOUN
cusj-5649	152	16	2	2	NUM
cusj-5649	152	17	to	to	PART
cusj-5649	152	18	selectively	selectively	ADV
cusj-5649	152	19	replicate	replicate	VERB
cusj-5649	152	20	within	within	ADP
cusj-5649	152	21	and	and	CCONJ
cusj-5649	152	22	destroy	destroy	VERB
cusj-5649	152	23	cancerous	cancerous	ADJ
cusj-5649	152	24	cells	cell	NOUN
cusj-5649	152	25	.	.	PUNCT
cusj-5649	153	1	successful	successful	ADJ
cusj-5649	153	2	oncolysis	oncolysis	NOUN
cusj-5649	153	3	with	with	ADP
cusj-5649	153	4	the	the	DET
cusj-5649	153	5	use	use	NOUN
cusj-5649	153	6	of	of	ADP
cusj-5649	153	7	poliovirus	poliovirus	NOUN
cusj-5649	153	8	infection	infection	NOUN
cusj-5649	153	9	depends	depend	VERB
cusj-5649	153	10	directly	directly	ADV
cusj-5649	153	11	on	on	ADP
cusj-5649	153	12	the	the	DET
cusj-5649	153	13	presence	presence	NOUN
cusj-5649	153	14	of	of	ADP
cusj-5649	153	15	cd155	cd155	PROPN
cusj-5649	153	16	in	in	ADP
cusj-5649	153	17	targeted	target	VERB
cusj-5649	153	18	tumors	tumor	NOUN
cusj-5649	153	19	(	(	PUNCT
cusj-5649	153	20	sloan	sloan	NOUN
cusj-5649	153	21	,	,	PUNCT
cusj-5649	153	22	2005	2005	NUM
cusj-5649	153	23	)	)	PUNCT
cusj-5649	153	24	.	.	PUNCT
cusj-5649	154	1	poliovirus	poliovirus	NOUN
cusj-5649	154	2	has	have	VERB
cusj-5649	154	3	a	a	DET
cusj-5649	154	4	plus	plus	ADJ
cusj-5649	154	5	-	-	PUNCT
cusj-5649	154	6	strand	strand	NOUN
cusj-5649	154	7	rna	rna	NOUN
cusj-5649	154	8	genome	genome	NOUN
cusj-5649	154	9	,	,	PUNCT
cusj-5649	154	10	the	the	DET
cusj-5649	154	11	translation	translation	NOUN
cusj-5649	154	12	of	of	ADP
cusj-5649	154	13	which	which	PRON
cusj-5649	154	14	depends	depend	VERB
cusj-5649	154	15	on	on	ADP
cusj-5649	154	16	a	a	DET
cusj-5649	154	17	tissue	tissue	NOUN
cusj-5649	154	18	-	-	PUNCT
cusj-5649	154	19	speci"c	speci"c	NOUN
cusj-5649	154	20	internal	internal	ADJ
cusj-5649	154	21	ribocolumbia	ribocolumbia	NOUN
cusj-5649	154	22	undergraduate	undergraduate	PROPN
cusj-5649	154	23	science	science	PROPN
cusj-5649	154	24	journal	journal	PROPN
cusj-5649	154	25	open	open	ADJ
cusj-5649	154	26	-	-	PUNCT
cusj-5649	154	27	access	access	NOUN
cusj-5649	154	28	publication	publication	NOUN
cusj-5649	154	29	|	|	ADV
cusj-5649	154	30	http://cusj.columbia.com	http://cusj.columbia.com	X
cusj-5649	154	31	46	46	NUM
cusj-5649	154	32	cusjvolume	cusjvolume	VERB
cusj-5649	154	33	5spring	5spring	NUM
cusj-5649	154	34	2011	2011	NUM
cusj-5649	154	35	columbia	columbia	PROPN
cusj-5649	154	36	undergraduate	undergraduate	NOUN
cusj-5649	154	37	sci	sci	PROPN
cusj-5649	154	38	j	j	PROPN
cusj-5649	154	39	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	154	40	v	v	ADP
cusj-5649	154	41	ir	ir	PROPN
cusj-5649	154	42	o	o	NOUN
cusj-5649	155	1	lo	lo	NOUN
cusj-5649	155	2	g	g	PROPN
cusj-5649	155	3	y	y	PROPN
cusj-5649	155	4	cusjcolumbia	cusjcolumbia	ADJ
cusj-5649	155	5	undergraduate	undergraduate	NOUN
cusj-5649	155	6	science	science	NOUN
cusj-5649	155	7	journalresearch	journalresearch	NOUN
cusj-5649	155	8	articles	article	VERB
cusj-5649	155	9	47cusj	47cusj	PRON
cusj-5649	155	10	volume	volume	NOUN
cusj-5649	155	11	5spring	5spring	PROPN
cusj-5649	155	12	2011	2011	NUM
cusj-5649	156	1	columbia	columbia	PROPN
cusj-5649	156	2	undergraduate	undergraduate	NOUN
cusj-5649	156	3	sci	sci	PROPN
cusj-5649	156	4	j	j	PROPN
cusj-5649	156	5	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	156	6	v	v	ADP
cusj-5649	156	7	ir	ir	PROPN
cusj-5649	156	8	o	o	NOUN
cusj-5649	157	1	lo	lo	INTJ
cusj-5649	157	2	g	g	PROPN
cusj-5649	157	3	y	y	PROPN
cusj-5649	157	4	hyde	hyde	PROPN
cusj-5649	157	5	at	at	ADP
cusj-5649	157	6	4	4	NUM
cusj-5649	157	7	°	°	ADP
cusj-5649	157	8	c	c	NOUN
cusj-5649	157	9	for	for	ADP
cusj-5649	157	10	20	20	NUM
cusj-5649	157	11	minutes	minute	NOUN
cusj-5649	157	12	.	.	PUNCT
cusj-5649	158	1	after	after	ADP
cusj-5649	158	2	3	3	NUM
cusj-5649	158	3	washes	wash	NOUN
cusj-5649	158	4	with	with	ADP
cusj-5649	158	5	phosphate	phosphate	NOUN
cusj-5649	158	6	-	-	PUNCT
cusj-5649	158	7	bu!ered	bu!ere	VERB
cusj-5649	158	8	saline	saline	NOUN
cusj-5649	158	9	(	(	PUNCT
cusj-5649	158	10	pbs	pbs	PROPN
cusj-5649	158	11	)	)	PUNCT
cusj-5649	158	12	at	at	ADP
cusj-5649	158	13	room	room	NOUN
cusj-5649	158	14	temperature	temperature	NOUN
cusj-5649	158	15	,	,	PUNCT
cusj-5649	158	16	the	the	DET
cusj-5649	158	17	cells	cell	NOUN
cusj-5649	158	18	were	be	AUX
cusj-5649	158	19	stained	stain	VERB
cusj-5649	158	20	with	with	ADP
cusj-5649	158	21	the	the	DET
cusj-5649	158	22	nuclei	nuclei	PROPN
cusj-5649	158	23	stain	stain	NOUN
cusj-5649	158	24	hoechst	hoechst	NOUN
cusj-5649	158	25	(	(	PUNCT
cusj-5649	158	26	calbiochem	calbiochem	PROPN
cusj-5649	158	27	/	/	SYM
cusj-5649	158	28	emd	emd	PROPN
cusj-5649	158	29	)	)	PUNCT
cusj-5649	158	30	at	at	ADP
cusj-5649	158	31	a	a	DET
cusj-5649	158	32	1000x	1000x	NUM
cusj-5649	158	33	dilution	dilution	NOUN
cusj-5649	158	34	of	of	ADP
cusj-5649	158	35	10µg/10µl	10µg/10µl	NUM
cusj-5649	158	36	for	for	ADP
cusj-5649	158	37	30	30	NUM
cusj-5649	158	38	minutes	minute	NOUN
cusj-5649	158	39	at	at	ADP
cusj-5649	158	40	4	4	NUM
cusj-5649	158	41	°	°	NOUN
cusj-5649	158	42	c	c	NOUN
cusj-5649	158	43	.	.	PUNCT
cusj-5649	159	1	"	"	PUNCT
cusj-5649	159	2	e	e	NOUN
cusj-5649	159	3	cells	cell	NOUN
cusj-5649	159	4	were	be	AUX
cusj-5649	159	5	washed	wash	VERB
cusj-5649	159	6	again	again	ADV
cusj-5649	159	7	3	3	NUM
cusj-5649	159	8	times	time	NOUN
cusj-5649	159	9	with	with	ADP
cusj-5649	159	10	pbs	pbs	PROPN
cusj-5649	159	11	and	and	CCONJ
cusj-5649	159	12	then	then	ADV
cusj-5649	159	13	plated	plate	VERB
cusj-5649	159	14	onto	onto	ADP
cusj-5649	159	15	glass	glass	NOUN
cusj-5649	159	16	coverslips	coverslip	NOUN
cusj-5649	159	17	for	for	ADP
cusj-5649	159	18	analysis	analysis	NOUN
cusj-5649	159	19	.	.	PUNCT
cusj-5649	160	1	data	datum	NOUN
cusj-5649	160	2	analysis	analysis	NOUN
cusj-5649	160	3	"	"	PUNCT
cusj-5649	160	4	e	e	NOUN
cusj-5649	160	5	number	number	NOUN
cusj-5649	160	6	of	of	ADP
cusj-5649	160	7	nuclei	nucleus	NOUN
cusj-5649	160	8	on	on	ADP
cusj-5649	160	9	the	the	DET
cusj-5649	160	10	bottom	bottom	NOUN
cusj-5649	160	11	of	of	ADP
cusj-5649	160	12	each	each	PRON
cusj-5649	160	13	of	of	ADP
cusj-5649	160	14	both	both	DET
cusj-5649	160	15	control	control	NOUN
cusj-5649	160	16	#	#	ADJ
cusj-5649	160	17	lters	lter	NOUN
cusj-5649	160	18	was	be	AUX
cusj-5649	160	19	counted	count	VERB
cusj-5649	160	20	in	in	ADP
cusj-5649	160	21	two	two	NUM
cusj-5649	160	22	low	low	ADJ
cusj-5649	160	23	power	power	NOUN
cusj-5649	160	24	#	#	NOUN
cusj-5649	160	25	elds	eld	NOUN
cusj-5649	160	26	(	(	PUNCT
cusj-5649	160	27	25x	25x	NOUN
cusj-5649	160	28	)	)	PUNCT
cusj-5649	160	29	of	of	ADP
cusj-5649	160	30	a	a	DET
cusj-5649	160	31	zeiss	zeiss	PROPN
cusj-5649	160	32	axioplan	axioplan	NOUN
cusj-5649	160	33	microscope	microscope	NOUN
cusj-5649	160	34	and	and	CCONJ
cusj-5649	160	35	averaged	average	VERB
cusj-5649	160	36	.	.	PUNCT
cusj-5649	161	1	"	"	PUNCT
cusj-5649	161	2	e	e	X
cusj-5649	161	3	nuclei	nucleus	NOUN
cusj-5649	161	4	on	on	ADP
cusj-5649	161	5	the	the	DET
cusj-5649	161	6	top	top	NOUN
cusj-5649	161	7	of	of	ADP
cusj-5649	161	8	the	the	DET
cusj-5649	161	9	#	#	ADJ
cusj-5649	161	10	lters	lter	NOUN
cusj-5649	161	11	was	be	AUX
cusj-5649	161	12	also	also	ADV
cusj-5649	161	13	counted	count	VERB
cusj-5649	161	14	in	in	ADP
cusj-5649	161	15	two	two	NUM
cusj-5649	161	16	low	low	ADJ
cusj-5649	161	17	power	power	NOUN
cusj-5649	161	18	#	#	NOUN
cusj-5649	161	19	elds	eld	NOUN
cusj-5649	161	20	and	and	CCONJ
cusj-5649	161	21	averaged	average	VERB
cusj-5649	161	22	in	in	ADP
cusj-5649	161	23	order	order	NOUN
cusj-5649	161	24	to	to	PART
cusj-5649	161	25	further	far	ADV
cusj-5649	161	26	assess	assess	VERB
cusj-5649	161	27	the	the	DET
cusj-5649	161	28	rate	rate	NOUN
cusj-5649	161	29	of	of	ADP
cusj-5649	161	30	migration	migration	NOUN
cusj-5649	161	31	in	in	ADP
cusj-5649	161	32	normal	normal	ADJ
cusj-5649	161	33	c6	c6	PROPN
cusj-5649	161	34	cell	cell	NOUN
cusj-5649	161	35	lines	line	NOUN
cusj-5649	161	36	.	.	PUNCT
cusj-5649	162	1	lysates	lysate	NOUN
cusj-5649	162	2	lysis	lysis	VERB
cusj-5649	162	3	bu!er	bu!er	PROPN
cusj-5649	162	4	(	(	PUNCT
cusj-5649	162	5	ripa	ripa	PROPN
cusj-5649	162	6	bu!er	bu!er	PROPN
cusj-5649	162	7	)	)	PUNCT
cusj-5649	162	8	was	be	AUX
cusj-5649	162	9	prepared	prepare	VERB
cusj-5649	162	10	(	(	PUNCT
cusj-5649	162	11	1	1	NUM
cusj-5649	162	12	m	m	NOUN
cusj-5649	162	13	ph	ph	ADJ
cusj-5649	162	14	8	8	NUM
cusj-5649	162	15	tris	tris	NOUN
cusj-5649	162	16	,	,	PUNCT
cusj-5649	162	17	5	5	NUM
cusj-5649	162	18	m	m	NOUN
cusj-5649	162	19	nacl	nacl	NOUN
cusj-5649	162	20	,	,	PUNCT
cusj-5649	162	21	20	20	NUM
cusj-5649	162	22	%	%	NOUN
cusj-5649	162	23	np40	np40	PROPN
cusj-5649	162	24	,	,	PUNCT
cusj-5649	162	25	10	10	NUM
cusj-5649	162	26	%	%	NOUN
cusj-5649	162	27	sds	sds	NOUN
cusj-5649	162	28	,	,	PUNCT
cusj-5649	162	29	distilled	distil	VERB
cusj-5649	162	30	h20	h20	PROPN
cusj-5649	162	31	up	up	ADP
cusj-5649	162	32	to	to	PART
cusj-5649	162	33	50	50	NUM
cusj-5649	162	34	ml	ml	NOUN
cusj-5649	162	35	)	)	PUNCT
cusj-5649	162	36	and	and	CCONJ
cusj-5649	162	37	stored	store	VERB
cusj-5649	162	38	at	at	ADP
cusj-5649	162	39	4	4	NUM
cusj-5649	162	40	°	°	NOUN
cusj-5649	162	41	c	c	NOUN
cusj-5649	162	42	.	.	PUNCT
cusj-5649	163	1	5x	5x	NOUN
cusj-5649	163	2	running	run	VERB
cusj-5649	163	3	bu!er	bu!er	NOUN
cusj-5649	163	4	(	(	PUNCT
cusj-5649	163	5	7.5	7.5	NUM
cusj-5649	163	6	g	g	NOUN
cusj-5649	163	7	tris	tris	NOUN
cusj-5649	163	8	,	,	PUNCT
cusj-5649	163	9	47	47	NUM
cusj-5649	163	10	g	g	NOUN
cusj-5649	163	11	glycine	glycine	NOUN
cusj-5649	163	12	,	,	PUNCT
cusj-5649	163	13	25	25	NUM
cusj-5649	163	14	ml	ml	NUM
cusj-5649	163	15	10	10	NUM
cusj-5649	163	16	%	%	NOUN
cusj-5649	163	17	sds	sds	NOUN
cusj-5649	163	18	,	,	PUNCT
cusj-5649	163	19	distilled	distil	VERB
cusj-5649	163	20	h20	h20	PROPN
cusj-5649	163	21	up	up	ADP
cusj-5649	163	22	to	to	ADP
cusj-5649	163	23	500	500	NUM
cusj-5649	163	24	ml	ml	NOUN
cusj-5649	163	25	)	)	PUNCT
cusj-5649	163	26	,	,	PUNCT
cusj-5649	163	27	5x	5x	NUM
cusj-5649	163	28	transfer	transfer	NOUN
cusj-5649	163	29	bu!er	bu!er	NOUN
cusj-5649	163	30	(	(	PUNCT
cusj-5649	163	31	9.5	9.5	NUM
cusj-5649	163	32	g	g	NOUN
cusj-5649	163	33	tris	tris	NOUN
cusj-5649	163	34	,	,	PUNCT
cusj-5649	163	35	47	47	NUM
cusj-5649	163	36	g	g	NOUN
cusj-5649	163	37	glycine	glycine	NOUN
cusj-5649	163	38	,	,	PUNCT
cusj-5649	163	39	distilled	distil	VERB
cusj-5649	163	40	h20	h20	PROPN
cusj-5649	163	41	up	up	ADP
cusj-5649	163	42	to	to	ADP
cusj-5649	163	43	500	500	NUM
cusj-5649	163	44	ml	ml	NOUN
cusj-5649	163	45	)	)	PUNCT
cusj-5649	163	46	,	,	PUNCT
cusj-5649	163	47	and	and	CCONJ
cusj-5649	163	48	10x	10x	NUM
cusj-5649	163	49	tbs	tbs	NOUN
cusj-5649	163	50	(	(	PUNCT
cusj-5649	163	51	6	6	NUM
cusj-5649	163	52	g	g	NOUN
cusj-5649	163	53	tris	tris	NOUN
cusj-5649	163	54	,	,	PUNCT
cusj-5649	163	55	44	44	NUM
cusj-5649	163	56	g	g	NOUN
cusj-5649	163	57	nacl	nacl	NOUN
cusj-5649	163	58	,	,	PUNCT
cusj-5649	163	59	dh20	dh20	PROPN
cusj-5649	163	60	up	up	ADP
cusj-5649	163	61	to	to	PART
cusj-5649	163	62	500	500	NUM
cusj-5649	163	63	ml	ml	NOUN
cusj-5649	163	64	,	,	PUNCT
cusj-5649	163	65	ph	ph	NOUN
cusj-5649	163	66	7.4	7.4	NUM
cusj-5649	163	67	)	)	PUNCT
cusj-5649	163	68	were	be	AUX
cusj-5649	163	69	prepared	prepare	VERB
cusj-5649	163	70	and	and	CCONJ
cusj-5649	163	71	kept	keep	VERB
cusj-5649	163	72	at	at	ADP
cusj-5649	163	73	room	room	NOUN
cusj-5649	163	74	temperature	temperature	NOUN
cusj-5649	163	75	.	.	PUNCT
cusj-5649	164	1	0.5	0.5	NUM
cusj-5649	164	2	ml	ml	NOUN
cusj-5649	164	3	of	of	ADP
cusj-5649	164	4	edta	edta	NOUN
cusj-5649	164	5	was	be	AUX
cusj-5649	164	6	added	add	VERB
cusj-5649	164	7	to	to	ADP
cusj-5649	164	8	4.5	4.5	NUM
cusj-5649	164	9	ml	ml	NOUN
cusj-5649	164	10	of	of	ADP
cusj-5649	164	11	lysis	lysis	NOUN
cusj-5649	164	12	buffer	buffer	NOUN
cusj-5649	164	13	to	to	PART
cusj-5649	164	14	make	make	VERB
cusj-5649	164	15	a	a	DET
cusj-5649	164	16	10x	10x	ADJ
cusj-5649	164	17	stock	stock	NOUN
cusj-5649	164	18	of	of	ADP
cusj-5649	164	19	protease	protease	NOUN
cusj-5649	164	20	inhibitor	inhibitor	NOUN
cusj-5649	164	21	cocktail	cocktail	NOUN
cusj-5649	164	22	.	.	PUNCT
cusj-5649	165	1	"	"	PUNCT
cusj-5649	165	2	e	e	X
cusj-5649	165	3	cocktail	cocktail	NOUN
cusj-5649	165	4	was	be	AUX
cusj-5649	165	5	then	then	ADV
cusj-5649	165	6	diluted	dilute	VERB
cusj-5649	165	7	1:10	1:10	NUM
cusj-5649	165	8	in	in	ADP
cusj-5649	165	9	lysis	lysis	NOUN
cusj-5649	165	10	bu!er	bu!er	NOUN
cusj-5649	165	11	(	(	PUNCT
cusj-5649	165	12	50µl	50µl	NOUN
cusj-5649	165	13	to	to	ADP
cusj-5649	165	14	450µl	450µl	NOUN
cusj-5649	165	15	)	)	PUNCT
cusj-5649	165	16	.	.	PUNCT
cusj-5649	166	1	cells	cell	NOUN
cusj-5649	166	2	were	be	AUX
cusj-5649	166	3	washed	wash	VERB
cusj-5649	166	4	twice	twice	ADV
cusj-5649	166	5	with	with	ADP
cusj-5649	166	6	pbs	pbs	PROPN
cusj-5649	166	7	and	and	CCONJ
cusj-5649	166	8	250µl	250µl	NOUN
cusj-5649	166	9	of	of	ADP
cusj-5649	166	10	the	the	DET
cusj-5649	166	11	lysis	lysis	NOUN
cusj-5649	166	12	bu!er	bu!er	NOUN
cusj-5649	166	13	mixture	mixture	NOUN
cusj-5649	166	14	was	be	AUX
cusj-5649	166	15	added	add	VERB
cusj-5649	166	16	directly	directly	ADV
cusj-5649	166	17	to	to	ADP
cusj-5649	166	18	the	the	DET
cusj-5649	166	19	tissue	tissue	NOUN
cusj-5649	166	20	culture	culture	NOUN
cusj-5649	166	21	dish	dish	NOUN
cusj-5649	166	22	.	.	PUNCT
cusj-5649	167	1	cells	cell	NOUN
cusj-5649	167	2	were	be	AUX
cusj-5649	167	3	scraped	scrape	VERB
cusj-5649	167	4	and	and	CCONJ
cusj-5649	167	5	pipeted	pipete	VERB
cusj-5649	167	6	to	to	ADP
cusj-5649	167	7	an	an	DET
cusj-5649	167	8	epindorph	epindorph	NOUN
cusj-5649	167	9	tube	tube	NOUN
cusj-5649	167	10	,	,	PUNCT
cusj-5649	167	11	vortexed	vortexe	VERB
cusj-5649	167	12	for	for	ADP
cusj-5649	167	13	10	10	NUM
cusj-5649	167	14	seconds	second	NOUN
cusj-5649	167	15	and	and	CCONJ
cusj-5649	167	16	returned	return	VERB
cusj-5649	167	17	to	to	ADP
cusj-5649	167	18	ice	ice	NOUN
cusj-5649	167	19	,	,	PUNCT
cusj-5649	167	20	and	and	CCONJ
cusj-5649	167	21	then	then	ADV
cusj-5649	167	22	vortexed	vortexe	VERB
cusj-5649	167	23	for	for	ADP
cusj-5649	167	24	30	30	NUM
cusj-5649	167	25	seconds	second	NOUN
cusj-5649	167	26	.	.	PUNCT
cusj-5649	168	1	cells	cell	NOUN
cusj-5649	168	2	were	be	AUX
cusj-5649	168	3	then	then	ADV
cusj-5649	168	4	spun	spin	VERB
cusj-5649	168	5	for	for	ADP
cusj-5649	168	6	ten	ten	NUM
cusj-5649	168	7	minutes	minute	NOUN
cusj-5649	168	8	at	at	ADP
cusj-5649	168	9	1600	1600	NUM
cusj-5649	168	10	rpm	rpm	NOUN
cusj-5649	168	11	and	and	CCONJ
cusj-5649	168	12	the	the	DET
cusj-5649	168	13	supernatant	supernatant	NOUN
cusj-5649	168	14	was	be	AUX
cusj-5649	168	15	pulled	pull	VERB
cusj-5649	168	16	o	o	NOUN
cusj-5649	168	17	!	!	PUNCT
cusj-5649	169	1	into	into	ADP
cusj-5649	169	2	a	a	DET
cusj-5649	169	3	new	new	ADJ
cusj-5649	169	4	epindorph	epindorph	NOUN
cusj-5649	169	5	.	.	PUNCT
cusj-5649	170	1	"	"	PUNCT
cusj-5649	170	2	e	e	X
cusj-5649	170	3	lysates	lysate	NOUN
cusj-5649	170	4	were	be	AUX
cusj-5649	170	5	snap	snap	ADJ
cusj-5649	170	6	-	-	PUNCT
cusj-5649	170	7	frozen	frozen	ADJ
cusj-5649	170	8	with	with	ADP
cusj-5649	170	9	liquid	liquid	ADJ
cusj-5649	170	10	nitrogen	nitrogen	NOUN
cusj-5649	170	11	and	and	CCONJ
cusj-5649	170	12	stored	store	VERB
cusj-5649	170	13	at	at	ADP
cusj-5649	170	14	-80	-80	NOUN
cusj-5649	170	15	°	°	NOUN
cusj-5649	170	16	c	c	NOUN
cusj-5649	170	17	until	until	ADP
cusj-5649	170	18	quanitation	quanitation	NOUN
cusj-5649	170	19	.	.	PUNCT
cusj-5649	171	1	western	western	ADJ
cusj-5649	171	2	blot	blot	NOUN
cusj-5649	171	3	analysis	analysis	NOUN
cusj-5649	171	4	cd155	cd155	NOUN
cusj-5649	171	5	expression	expression	NOUN
cusj-5649	171	6	levels	level	NOUN
cusj-5649	171	7	were	be	AUX
cusj-5649	171	8	determined	determine	VERB
cusj-5649	171	9	by	by	ADP
cusj-5649	171	10	using	use	VERB
cusj-5649	171	11	a	a	DET
cusj-5649	171	12	western	western	ADJ
cusj-5649	171	13	blot	blot	NOUN
cusj-5649	171	14	procedure	procedure	NOUN
cusj-5649	171	15	.	.	PUNCT
cusj-5649	172	1	24	24	NUM
cusj-5649	172	2	µl	µl	ADP
cusj-5649	172	3	protein	protein	NOUN
cusj-5649	172	4	lysate	lysate	NOUN
cusj-5649	172	5	was	be	AUX
cusj-5649	172	6	mixed	mix	VERB
cusj-5649	172	7	with	with	ADP
cusj-5649	172	8	8	8	NUM
cusj-5649	172	9	µl	µl	ADP
cusj-5649	172	10	4x	4x	NUM
cusj-5649	172	11	sample	sample	NOUN
cusj-5649	172	12	bu!er	bu!er	NOUN
cusj-5649	172	13	(	(	PUNCT
cusj-5649	172	14	20	20	NUM
cusj-5649	172	15	ml	ml	NUM
cusj-5649	172	16	40	40	NUM
cusj-5649	172	17	%	%	NOUN
cusj-5649	172	18	glycerol	glycerol	NOUN
cusj-5649	172	19	,	,	PUNCT
cusj-5649	172	20	4	4	NUM
cusj-5649	172	21	g	g	PROPN
cusj-5649	172	22	sds	sds	PROPN
cusj-5649	172	23	,	,	PUNCT
cusj-5649	172	24	.01	.01	NUM
cusj-5649	172	25	g	g	NOUN
cusj-5649	172	26	.02	.02	NUM
cusj-5649	172	27	%	%	NOUN
cusj-5649	172	28	bromophenol	bromophenol	NOUN
cusj-5649	172	29	-	-	PUNCT
cusj-5649	172	30	blue	blue	ADJ
cusj-5649	172	31	,	,	PUNCT
cusj-5649	172	32	5	5	NUM
cusj-5649	172	33	ml	ml	NOUN
cusj-5649	172	34	beta	beta	NOUN
cusj-5649	172	35	-	-	PUNCT
cusj-5649	172	36	mercaptoethanol	mercaptoethanol	NOUN
cusj-5649	172	37	(	(	PUNCT
cusj-5649	172	38	bme	bme	NOUN
cusj-5649	172	39	)	)	PUNCT
cusj-5649	172	40	,	,	PUNCT
cusj-5649	172	41	45ml	45ml	ADJ
cusj-5649	172	42	dh20	dh20	PROPN
cusj-5649	172	43	)	)	PUNCT
cusj-5649	172	44	and	and	CCONJ
cusj-5649	172	45	boiled	boil	VERB
cusj-5649	172	46	for	for	ADP
cusj-5649	172	47	ten	ten	NUM
cusj-5649	172	48	minutes	minute	NOUN
cusj-5649	172	49	.	.	PUNCT
cusj-5649	173	1	10	10	NUM
cusj-5649	173	2	%	%	NOUN
cusj-5649	173	3	stacking	stacking	NOUN
cusj-5649	173	4	and	and	CCONJ
cusj-5649	173	5	separating	separate	VERB
cusj-5649	173	6	acrylamide	acrylamide	NOUN
cusj-5649	173	7	gels	gel	NOUN
cusj-5649	173	8	were	be	AUX
cusj-5649	173	9	prepared	prepare	VERB
cusj-5649	173	10	according	accord	VERB
cusj-5649	173	11	to	to	ADP
cusj-5649	173	12	page	page	NOUN
cusj-5649	173	13	recipe	recipe	NOUN
cusj-5649	173	14	calculator	calculator	NOUN
cusj-5649	173	15	(	(	PUNCT
cusj-5649	173	16	chang	chang	PROPN
cusj-5649	173	17	bioscience	bioscience	PROPN
cusj-5649	173	18	)	)	PUNCT
cusj-5649	173	19	and	and	CCONJ
cusj-5649	173	20	placed	place	VERB
cusj-5649	173	21	into	into	ADP
cusj-5649	173	22	the	the	DET
cusj-5649	173	23	chamber	chamber	NOUN
cusj-5649	173	24	(	(	PUNCT
cusj-5649	173	25	vwr	vwr	PROPN
cusj-5649	173	26	)	)	PUNCT
cusj-5649	173	27	,	,	PUNCT
cusj-5649	173	28	followed	follow	VERB
cusj-5649	173	29	by	by	ADP
cusj-5649	173	30	the	the	DET
cusj-5649	173	31	addition	addition	NOUN
cusj-5649	173	32	of	of	ADP
cusj-5649	173	33	1x	1x	NUM
cusj-5649	173	34	running	run	VERB
cusj-5649	173	35	bu!er	bu!er	NOUN
cusj-5649	173	36	up	up	ADP
cusj-5649	173	37	to	to	ADP
cusj-5649	173	38	the	the	DET
cusj-5649	173	39	brim	brim	NOUN
cusj-5649	173	40	of	of	ADP
cusj-5649	173	41	the	the	DET
cusj-5649	173	42	apparatus	apparatus	NOUN
cusj-5649	173	43	.	.	PUNCT
cusj-5649	174	1	"	"	PUNCT
cusj-5649	174	2	e	e	X
cusj-5649	174	3	protein	protein	NOUN
cusj-5649	174	4	mixture	mixture	NOUN
cusj-5649	174	5	,	,	PUNCT
cusj-5649	174	6	along	along	ADP
cusj-5649	174	7	with	with	ADP
cusj-5649	174	8	prestained	prestained	ADJ
cusj-5649	174	9	standard	standard	NOUN
cusj-5649	174	10	(	(	PUNCT
cusj-5649	174	11	biorad	biorad	NOUN
cusj-5649	174	12	)	)	PUNCT
cusj-5649	174	13	was	be	AUX
cusj-5649	174	14	then	then	ADV
cusj-5649	174	15	loaded	load	VERB
cusj-5649	174	16	into	into	ADP
cusj-5649	174	17	the	the	DET
cusj-5649	174	18	wells	well	NOUN
cusj-5649	174	19	and	and	CCONJ
cusj-5649	174	20	run	run	VERB
cusj-5649	174	21	at	at	ADP
cusj-5649	174	22	110v	110v	PROPN
cusj-5649	174	23	for	for	ADP
cusj-5649	174	24	approximately	approximately	ADV
cusj-5649	174	25	two	two	NUM
cusj-5649	174	26	hours	hour	NOUN
cusj-5649	174	27	.	.	PUNCT
cusj-5649	175	1	after	after	SCONJ
cusj-5649	175	2	the	the	DET
cusj-5649	175	3	gel	gel	NOUN
cusj-5649	175	4	was	be	AUX
cusj-5649	175	5	run	run	VERB
cusj-5649	175	6	,	,	PUNCT
cusj-5649	175	7	it	it	PRON
cusj-5649	175	8	was	be	AUX
cusj-5649	175	9	placed	place	VERB
cusj-5649	175	10	directly	directly	ADV
cusj-5649	175	11	into	into	ADP
cusj-5649	175	12	1x	1x	NUM
cusj-5649	175	13	transfer	transfer	NOUN
cusj-5649	175	14	bu!er	bu!er	NOUN
cusj-5649	175	15	.	.	PUNCT
cusj-5649	176	1	"	"	PUNCT
cusj-5649	176	2	e	e	NOUN
cusj-5649	176	3	nitrocellulose	nitrocellulose	NOUN
cusj-5649	176	4	was	be	AUX
cusj-5649	176	5	prewet	prewet	ADJ
cusj-5649	176	6	in	in	ADP
cusj-5649	176	7	sterile	sterile	ADJ
cusj-5649	176	8	water	water	NOUN
cusj-5649	176	9	to	to	PART
cusj-5649	176	10	activate	activate	VERB
cusj-5649	176	11	and	and	CCONJ
cusj-5649	176	12	the	the	DET
cusj-5649	176	13	gels	gel	NOUN
cusj-5649	176	14	were	be	AUX
cusj-5649	176	15	subjected	subject	VERB
cusj-5649	176	16	to	to	ADP
cusj-5649	176	17	overnight	overnight	ADJ
cusj-5649	176	18	electrophoretic	electrophoretic	ADJ
cusj-5649	176	19	transfer	transfer	NOUN
cusj-5649	176	20	(	(	PUNCT
cusj-5649	176	21	.03amp	.03amp	NOUN
cusj-5649	176	22	)	)	PUNCT
cusj-5649	176	23	following	follow	VERB
cusj-5649	176	24	standard	standard	ADJ
cusj-5649	176	25	procedures	procedure	NOUN
cusj-5649	176	26	.	.	PUNCT
cusj-5649	177	1	membranes	membrane	NOUN
cusj-5649	177	2	were	be	AUX
cusj-5649	177	3	rinsed	rinse	VERB
cusj-5649	177	4	in	in	ADP
cusj-5649	177	5	sterile	sterile	ADJ
cusj-5649	177	6	water	water	NOUN
cusj-5649	177	7	and	and	CCONJ
cusj-5649	177	8	then	then	ADV
cusj-5649	177	9	blocked	block	VERB
cusj-5649	177	10	with	with	ADP
cusj-5649	177	11	50	50	NUM
cusj-5649	177	12	ml	ml	NOUN
cusj-5649	177	13	of	of	ADP
cusj-5649	177	14	tris	tris	ADJ
cusj-5649	177	15	-	-	PUNCT
cusj-5649	177	16	bu!ered	bu!ere	VERB
cusj-5649	177	17	saline	saline	NOUN
cusj-5649	177	18	tween-20	tween-20	PROPN
cusj-5649	177	19	with	with	ADP
cusj-5649	177	20	0.25	0.25	NUM
cusj-5649	177	21	g	g	PROPN
cusj-5649	177	22	bsa	bsa	PROPN
cusj-5649	177	23	(	(	PUNCT
cusj-5649	177	24	tbstb	tbstb	PROPN
cusj-5649	177	25	)	)	PUNCT
cusj-5649	178	1	+	+	CCONJ
cusj-5649	178	2	5	5	NUM
cusj-5649	178	3	%	%	NOUN
cusj-5649	178	4	milk	milk	NOUN
cusj-5649	178	5	for	for	ADP
cusj-5649	178	6	one	one	NUM
cusj-5649	178	7	hour	hour	NOUN
cusj-5649	178	8	on	on	ADP
cusj-5649	178	9	the	the	DET
cusj-5649	178	10	shaker	shaker	NOUN
cusj-5649	178	11	at	at	ADP
cusj-5649	178	12	room	room	NOUN
cusj-5649	178	13	temperature	temperature	NOUN
cusj-5649	178	14	.	.	PUNCT
cusj-5649	179	1	after	after	ADP
cusj-5649	179	2	soaking	soak	VERB
cusj-5649	179	3	,	,	PUNCT
cusj-5649	179	4	the	the	DET
cusj-5649	179	5	blots	blot	NOUN
cusj-5649	179	6	were	be	AUX
cusj-5649	179	7	treated	treat	VERB
cusj-5649	179	8	with	with	ADP
cusj-5649	179	9	anti	anti	ADJ
cusj-5649	179	10	-	-	ADJ
cusj-5649	179	11	necl-5	necl-5	NUM
cusj-5649	179	12	rat	rat	NOUN
cusj-5649	179	13	monoclonal	monoclonal	NOUN
cusj-5649	179	14	antibody	antibody	NOUN
cusj-5649	179	15	clone	clone	NOUN
cusj-5649	179	16	1a88	1a88	NUM
cusj-5649	179	17	(	(	PUNCT
cusj-5649	179	18	gift	gift	NOUN
cusj-5649	179	19	of	of	ADP
cusj-5649	179	20	dr	dr	PROPN
cusj-5649	179	21	.	.	PROPN
cusj-5649	179	22	yoshimi	yoshimi	PROPN
cusj-5649	179	23	takai	takai	PROPN
cusj-5649	179	24	,	,	PUNCT
cusj-5649	179	25	stored	store	VERB
cusj-5649	179	26	at	at	ADP
cusj-5649	179	27	-80	-80	NOUN
cusj-5649	179	28	°	°	NOUN
cusj-5649	179	29	c	c	NOUN
cusj-5649	179	30	)	)	PUNCT
cusj-5649	179	31	diluted	dilute	VERB
cusj-5649	179	32	1:1000	1:1000	NUM
cusj-5649	179	33	in	in	ADP
cusj-5649	179	34	tbstb	tbstb	NOUN
cusj-5649	179	35	and	and	CCONJ
cusj-5649	179	36	incubated	incubate	VERB
cusj-5649	179	37	overnight	overnight	ADV
cusj-5649	179	38	at	at	ADP
cusj-5649	179	39	4	4	NUM
cusj-5649	179	40	°	°	NOUN
cusj-5649	179	41	c	c	NOUN
cusj-5649	179	42	.	.	PUNCT
cusj-5649	180	1	after	after	ADP
cusj-5649	180	2	the	the	DET
cusj-5649	180	3	removal	removal	NOUN
cusj-5649	180	4	of	of	ADP
cusj-5649	180	5	the	the	DET
cusj-5649	180	6	primary	primary	ADJ
cusj-5649	180	7	antibody	antibody	NOUN
cusj-5649	180	8	and	and	CCONJ
cusj-5649	180	9	3	3	NUM
cusj-5649	180	10	consecutive	consecutive	ADJ
cusj-5649	180	11	ten	ten	NUM
cusj-5649	180	12	-	-	PUNCT
cusj-5649	180	13	minute	minute	NOUN
cusj-5649	180	14	washes	wash	NOUN
cusj-5649	180	15	of	of	ADP
cusj-5649	180	16	tbst	tbst	NOUN
cusj-5649	180	17	,	,	PUNCT
cusj-5649	180	18	the	the	DET
cusj-5649	180	19	last	last	ADJ
cusj-5649	180	20	with	with	ADP
cusj-5649	180	21	tbstb	tbstb	NOUN
cusj-5649	180	22	+	+	CCONJ
cusj-5649	180	23	5	5	NUM
cusj-5649	180	24	%	%	NOUN
cusj-5649	180	25	milk	milk	NOUN
cusj-5649	180	26	,	,	PUNCT
cusj-5649	180	27	the	the	DET
cusj-5649	180	28	membranes	membrane	NOUN
cusj-5649	180	29	were	be	AUX
cusj-5649	180	30	treated	treat	VERB
cusj-5649	180	31	with	with	ADP
cusj-5649	180	32	secondary	secondary	ADJ
cusj-5649	180	33	antimouse	antimouse	ADP
cusj-5649	180	34	igg	igg	PROPN
cusj-5649	180	35	-	-	PUNCT
cusj-5649	180	36	alkaline	alkaline	NOUN
cusj-5649	180	37	phosphatase	phosphatase	NOUN
cusj-5649	180	38	antibody	antibody	NOUN
cusj-5649	180	39	produced	produce	VERB
cusj-5649	180	40	in	in	ADP
cusj-5649	180	41	goat	goat	PROPN
cusj-5649	180	42	(	(	PUNCT
cusj-5649	180	43	sigma	sigma	PROPN
cusj-5649	180	44	,	,	PUNCT
cusj-5649	180	45	stored	store	VERB
cusj-5649	180	46	at	at	ADP
cusj-5649	180	47	4	4	NUM
cusj-5649	180	48	°	°	NOUN
cusj-5649	180	49	c	c	NOUN
cusj-5649	180	50	)	)	PUNCT
cusj-5649	180	51	diluted	dilute	VERB
cusj-5649	180	52	1:10,000	1:10,000	NUM
cusj-5649	180	53	in	in	ADP
cusj-5649	180	54	tbstb	tbstb	NOUN
cusj-5649	180	55	and	and	CCONJ
cusj-5649	180	56	set	set	VERB
cusj-5649	180	57	on	on	ADP
cusj-5649	180	58	the	the	DET
cusj-5649	180	59	shaker	shaker	NOUN
cusj-5649	180	60	for	for	ADP
cusj-5649	180	61	1	1	NUM
cusj-5649	180	62	hour	hour	NOUN
cusj-5649	180	63	.	.	PUNCT
cusj-5649	181	1	after	after	ADP
cusj-5649	181	2	three	three	NUM
cusj-5649	181	3	thorough	thorough	ADJ
cusj-5649	181	4	rinses	rinse	NOUN
cusj-5649	181	5	of	of	ADP
cusj-5649	181	6	the	the	DET
cusj-5649	181	7	blots	blot	NOUN
cusj-5649	181	8	with	with	ADP
cusj-5649	181	9	tbst	tbst	NOUN
cusj-5649	181	10	,	,	PUNCT
cusj-5649	181	11	they	they	PRON
cusj-5649	181	12	were	be	AUX
cusj-5649	181	13	treated	treat	VERB
cusj-5649	181	14	with	with	ADP
cusj-5649	181	15	bm	bm	PROPN
cusj-5649	181	16	purple	purple	PROPN
cusj-5649	181	17	(	(	PUNCT
cusj-5649	181	18	roche	roche	NOUN
cusj-5649	181	19	)	)	PUNCT
cusj-5649	181	20	until	until	ADP
cusj-5649	181	21	the	the	DET
cusj-5649	181	22	appearance	appearance	NOUN
cusj-5649	181	23	of	of	ADP
cusj-5649	181	24	protein	protein	NOUN
cusj-5649	181	25	bands	band	NOUN
cusj-5649	181	26	—	—	PUNCT
cusj-5649	181	27	after	after	ADP
cusj-5649	181	28	which	which	PRON
cusj-5649	181	29	they	they	PRON
cusj-5649	181	30	were	be	AUX
cusj-5649	181	31	stored	store	VERB
cusj-5649	181	32	at	at	ADP
cusj-5649	181	33	4	4	NUM
cusj-5649	181	34	°	°	ADP
cusj-5649	181	35	c	c	NOUN
cusj-5649	181	36	in	in	ADP
cusj-5649	181	37	tbst	tbst	PROPN
cusj-5649	181	38	.	.	PUNCT
cusj-5649	182	1	with	with	ADP
cusj-5649	182	2	two	two	NUM
cusj-5649	182	3	successful	successful	ADJ
cusj-5649	182	4	western	western	ADJ
cusj-5649	182	5	blots	blot	NOUN
cusj-5649	182	6	(	(	PUNCT
cusj-5649	182	7	see	see	VERB
cusj-5649	182	8	figures	figure	NOUN
cusj-5649	182	9	5	5	NUM
cusj-5649	182	10	and	and	CCONJ
cusj-5649	182	11	6	6	NUM
cusj-5649	182	12	)	)	PUNCT
cusj-5649	182	13	,	,	PUNCT
cusj-5649	182	14	we	we	PRON
cusj-5649	182	15	were	be	AUX
cusj-5649	182	16	able	able	ADJ
cusj-5649	182	17	to	to	PART
cusj-5649	182	18	formulate	formulate	VERB
cusj-5649	182	19	a	a	DET
cusj-5649	182	20	comprehensive	comprehensive	ADJ
cusj-5649	182	21	picture	picture	NOUN
cusj-5649	182	22	of	of	ADP
cusj-5649	182	23	c6	c6	PROPN
cusj-5649	182	24	glioma	glioma	NOUN
cusj-5649	182	25	migration	migration	NOUN
cusj-5649	182	26	in$uenced	in$uence	VERB
cusj-5649	182	27	by	by	ADP
cusj-5649	182	28	transfection	transfection	NOUN
cusj-5649	182	29	of	of	ADP
cusj-5649	182	30	pvr	pvr	NOUN
cusj-5649	182	31	.	.	PUNCT
cusj-5649	183	1	to	to	PART
cusj-5649	183	2	determine	determine	VERB
cusj-5649	183	3	if	if	SCONJ
cusj-5649	183	4	increased	increase	VERB
cusj-5649	183	5	synthesis	synthesis	NOUN
cusj-5649	183	6	of	of	ADP
cusj-5649	183	7	cd155	cd155	PROPN
cusj-5649	183	8	affects	affect	VERB
cusj-5649	183	9	the	the	DET
cusj-5649	183	10	migration	migration	NOUN
cusj-5649	183	11	of	of	ADP
cusj-5649	183	12	c6	c6	PROPN
cusj-5649	183	13	glioma	glioma	NOUN
cusj-5649	183	14	cells	cell	NOUN
cusj-5649	183	15	,	,	PUNCT
cusj-5649	183	16	we	we	PRON
cusj-5649	183	17	captured	capture	VERB
cusj-5649	183	18	two	two	NUM
cusj-5649	183	19	images	image	NOUN
cusj-5649	183	20	of	of	ADP
cusj-5649	183	21	each	each	DET
cusj-5649	183	22	control	control	NOUN
cusj-5649	183	23	and	and	CCONJ
cusj-5649	183	24	transfection	transfection	NOUN
cusj-5649	183	25	well	well	ADV
cusj-5649	183	26	,	,	PUNCT
cusj-5649	183	27	as	as	ADV
cusj-5649	183	28	well	well	ADV
cusj-5649	183	29	as	as	ADP
cusj-5649	183	30	one	one	NUM
cusj-5649	183	31	#	#	ADJ
cusj-5649	183	32	eld	eld	NOUN
cusj-5649	183	33	each	each	PRON
cusj-5649	183	34	of	of	ADP
cusj-5649	183	35	the	the	DET
cusj-5649	183	36	cells	cell	NOUN
cusj-5649	183	37	remaining	remain	VERB
cusj-5649	183	38	on	on	ADP
cusj-5649	183	39	the	the	DET
cusj-5649	183	40	top	top	NOUN
cusj-5649	183	41	of	of	ADP
cusj-5649	183	42	the	the	DET
cusj-5649	183	43	#	#	NOUN
cusj-5649	183	44	lter	lter	NOUN
cusj-5649	183	45	(	(	PUNCT
cusj-5649	183	46	see	see	VERB
cusj-5649	183	47	figures	figure	NOUN
cusj-5649	183	48	1	1	NUM
cusj-5649	183	49	,	,	PUNCT
cusj-5649	183	50	2	2	NUM
cusj-5649	183	51	,	,	PUNCT
cusj-5649	183	52	3	3	NUM
cusj-5649	183	53	)	)	PUNCT
cusj-5649	183	54	.	.	PUNCT
cusj-5649	184	1	it	it	PRON
cusj-5649	184	2	was	be	AUX
cusj-5649	184	3	not	not	PART
cusj-5649	184	4	immediately	immediately	ADV
cusj-5649	184	5	prevalent	prevalent	ADJ
cusj-5649	184	6	through	through	ADP
cusj-5649	184	7	qualitatively	qualitatively	ADV
cusj-5649	184	8	assessing	assess	VERB
cusj-5649	184	9	cell	cell	NOUN
cusj-5649	184	10	numbers	number	NOUN
cusj-5649	184	11	that	that	SCONJ
cusj-5649	184	12	a	a	DET
cusj-5649	184	13	substantial	substantial	ADJ
cusj-5649	184	14	increase	increase	NOUN
cusj-5649	184	15	in	in	ADP
cusj-5649	184	16	cell	cell	NOUN
cusj-5649	184	17	migration	migration	NOUN
cusj-5649	184	18	occurred	occur	VERB
cusj-5649	184	19	between	between	ADP
cusj-5649	184	20	the	the	DET
cusj-5649	184	21	control	control	NOUN
cusj-5649	184	22	and	and	CCONJ
cusj-5649	184	23	transfected	transfecte	VERB
cusj-5649	184	24	cells	cell	NOUN
cusj-5649	184	25	,	,	PUNCT
cusj-5649	184	26	but	but	CCONJ
cusj-5649	184	27	a	a	DET
cusj-5649	184	28	detailed	detailed	ADJ
cusj-5649	184	29	count	count	NOUN
cusj-5649	184	30	revealed	reveal	VERB
cusj-5649	184	31	an	an	DET
cusj-5649	184	32	increase	increase	NOUN
cusj-5649	184	33	.	.	PUNCT
cusj-5649	185	1	"	"	PUNCT
cusj-5649	185	2	e	e	X
cusj-5649	185	3	nuclei	nucleus	NOUN
cusj-5649	185	4	counts	count	VERB
cusj-5649	185	5	for	for	ADP
cusj-5649	185	6	the	the	DET
cusj-5649	185	7	control	control	NOUN
cusj-5649	185	8	#	#	SYM
cusj-5649	185	9	elds	eld	NOUN
cusj-5649	185	10	were	be	AUX
cusj-5649	185	11	315	315	NUM
cusj-5649	185	12	,	,	PUNCT
cusj-5649	185	13	355	355	NUM
cusj-5649	185	14	,	,	PUNCT
cusj-5649	185	15	260	260	NUM
cusj-5649	185	16	,	,	PUNCT
cusj-5649	185	17	and	and	CCONJ
cusj-5649	185	18	287	287	NUM
cusj-5649	185	19	,	,	PUNCT
cusj-5649	185	20	respectively	respectively	ADV
cusj-5649	185	21	.	.	PUNCT
cusj-5649	186	1	"	"	PUNCT
cusj-5649	186	2	e	e	NOUN
cusj-5649	186	3	numbers	number	NOUN
cusj-5649	186	4	of	of	ADP
cusj-5649	186	5	cells	cell	NOUN
cusj-5649	186	6	transfected	transfecte	VERB
cusj-5649	186	7	with	with	ADP
cusj-5649	186	8	the	the	DET
cusj-5649	186	9	pvr	pvr	NOUN
cusj-5649	186	10	expression	expression	NOUN
cusj-5649	186	11	vector	vector	NOUN
cusj-5649	186	12	that	that	PRON
cusj-5649	186	13	transversed	transverse	VERB
cusj-5649	186	14	the	the	DET
cusj-5649	186	15	matrix	matrix	NOUN
cusj-5649	186	16	were	be	AUX
cusj-5649	186	17	327	327	NUM
cusj-5649	186	18	,	,	PUNCT
cusj-5649	186	19	367	367	NUM
cusj-5649	186	20	,	,	PUNCT
cusj-5649	186	21	332	332	NUM
cusj-5649	186	22	,	,	PUNCT
cusj-5649	186	23	and	and	CCONJ
cusj-5649	186	24	392	392	NUM
cusj-5649	186	25	.	.	PUNCT
cusj-5649	187	1	"	"	PUNCT
cusj-5649	187	2	e	e	X
cusj-5649	187	3	average	average	NOUN
cusj-5649	187	4	of	of	ADP
cusj-5649	187	5	migrating	migrating	NOUN
cusj-5649	187	6	control	control	NOUN
cusj-5649	187	7	cells	cell	NOUN
cusj-5649	187	8	was	be	AUX
cusj-5649	187	9	304.25	304.25	NUM
cusj-5649	187	10	,	,	PUNCT
cusj-5649	187	11	in	in	ADP
cusj-5649	187	12	comparison	comparison	NOUN
cusj-5649	187	13	with	with	ADP
cusj-5649	187	14	the	the	DET
cusj-5649	187	15	transfection	transfection	NOUN
cusj-5649	187	16	average	average	NOUN
cusj-5649	187	17	of	of	ADP
cusj-5649	187	18	354.5	354.5	NUM
cusj-5649	187	19	.	.	PUNCT
cusj-5649	188	1	our	our	PRON
cusj-5649	188	2	data	datum	NOUN
cusj-5649	188	3	re$ect	re$ect	ADP
cusj-5649	188	4	an	an	DET
cusj-5649	188	5	average	average	ADJ
cusj-5649	188	6	percent	percent	NOUN
cusj-5649	188	7	increase	increase	NOUN
cusj-5649	188	8	of	of	ADP
cusj-5649	188	9	16.5	16.5	NUM
cusj-5649	188	10	%	%	NOUN
cusj-5649	188	11	.	.	PUNCT
cusj-5649	189	1	by	by	ADP
cusj-5649	189	2	conventional	conventional	ADJ
cusj-5649	189	3	standards	standard	NOUN
cusj-5649	189	4	according	accord	VERB
cusj-5649	189	5	to	to	ADP
cusj-5649	189	6	a	a	DET
cusj-5649	189	7	statistical	statistical	ADJ
cusj-5649	189	8	t	t	NOUN
cusj-5649	189	9	-	-	PUNCT
cusj-5649	189	10	test	test	NOUN
cusj-5649	189	11	(	(	PUNCT
cusj-5649	189	12	two	two	NUM
cusj-5649	189	13	-	-	PUNCT
cusj-5649	189	14	tailed	tail	VERB
cusj-5649	189	15	p	p	NOUN
cusj-5649	189	16	-	-	PUNCT
cusj-5649	189	17	value	value	NOUN
cusj-5649	189	18	of	of	ADP
cusj-5649	189	19	0.0957	0.0957	NUM
cusj-5649	189	20	)	)	PUNCT
cusj-5649	189	21	,	,	PUNCT
cusj-5649	189	22	this	this	DET
cusj-5649	189	23	di!erence	di!erence	NOUN
cusj-5649	189	24	is	be	AUX
cusj-5649	189	25	not	not	PART
cusj-5649	189	26	considered	consider	VERB
cusj-5649	189	27	to	to	PART
cusj-5649	189	28	be	be	AUX
cusj-5649	189	29	remarkably	remarkably	ADV
cusj-5649	189	30	signi#cant	signi#cant	NOUN
cusj-5649	189	31	.	.	PUNCT
cusj-5649	190	1	it	it	PRON
cusj-5649	190	2	is	be	AUX
cusj-5649	190	3	important	important	ADJ
cusj-5649	190	4	to	to	PART
cusj-5649	190	5	note	note	VERB
cusj-5649	190	6	,	,	PUNCT
cusj-5649	190	7	however	however	ADV
cusj-5649	190	8	,	,	PUNCT
cusj-5649	190	9	that	that	SCONJ
cusj-5649	190	10	the	the	DET
cusj-5649	190	11	second	second	ADJ
cusj-5649	190	12	round	round	NOUN
cusj-5649	190	13	of	of	ADP
cusj-5649	190	14	trans#lter	trans#lter	NOUN
cusj-5649	190	15	assays	assay	NOUN
cusj-5649	190	16	yielded	yield	VERB
cusj-5649	190	17	a	a	DET
cusj-5649	190	18	32.4	32.4	NUM
cusj-5649	190	19	%	%	NOUN
cusj-5649	190	20	increase	increase	NOUN
cusj-5649	190	21	in	in	ADP
cusj-5649	190	22	glioma	glioma	NOUN
cusj-5649	190	23	migration	migration	NOUN
cusj-5649	190	24	as	as	ADP
cusj-5649	190	25	a	a	DET
cusj-5649	190	26	result	result	NOUN
cusj-5649	190	27	of	of	ADP
cusj-5649	190	28	the	the	DET
cusj-5649	190	29	transfection	transfection	NOUN
cusj-5649	190	30	(	(	PUNCT
cusj-5649	190	31	see	see	VERB
cusj-5649	190	32	figure	figure	NOUN
cusj-5649	190	33	4	4	NUM
cusj-5649	190	34	)	)	PUNCT
cusj-5649	190	35	.	.	PUNCT
cusj-5649	191	1	in	in	ADP
cusj-5649	191	2	the	the	DET
cusj-5649	191	3	#	#	NOUN
cusj-5649	191	4	rst	rst	ADJ
cusj-5649	191	5	western	western	ADJ
cusj-5649	191	6	blot	blot	NOUN
cusj-5649	191	7	,	,	PUNCT
cusj-5649	191	8	which	which	PRON
cusj-5649	191	9	compared	compare	VERB
cusj-5649	191	10	cd155	cd155	NOUN
cusj-5649	191	11	protein	protein	NOUN
cusj-5649	191	12	levels	level	NOUN
cusj-5649	191	13	in	in	ADP
cusj-5649	191	14	c6	c6	PROPN
cusj-5649	191	15	control	control	NOUN
cusj-5649	191	16	cells	cell	NOUN
cusj-5649	191	17	to	to	ADP
cusj-5649	191	18	c6	c6	PROPN
cusj-5649	191	19	cells	cell	NOUN
cusj-5649	191	20	transfected	transfecte	VERB
cusj-5649	191	21	with	with	ADP
cusj-5649	191	22	the	the	DET
cusj-5649	191	23	pvr	pvr	NOUN
cusj-5649	191	24	over	over	ADP
cusj-5649	191	25	-	-	PUNCT
cusj-5649	191	26	expression	expression	NOUN
cusj-5649	191	27	vector	vector	NOUN
cusj-5649	191	28	,	,	PUNCT
cusj-5649	191	29	we	we	PRON
cusj-5649	191	30	could	could	AUX
cusj-5649	191	31	con#rm	con#rm	PROPN
cusj-5649	191	32	from	from	ADP
cusj-5649	191	33	the	the	DET
cusj-5649	191	34	location	location	NOUN
cusj-5649	191	35	of	of	ADP
cusj-5649	191	36	the	the	DET
cusj-5649	191	37	bands	band	NOUN
cusj-5649	191	38	(	(	PUNCT
cusj-5649	191	39	around	around	ADP
cusj-5649	191	40	40	40	NUM
cusj-5649	191	41	kda	kda	NOUN
cusj-5649	191	42	,	,	PUNCT
cusj-5649	191	43	just	just	ADV
cusj-5649	191	44	like	like	ADP
cusj-5649	191	45	the	the	DET
cusj-5649	191	46	mass	mass	NOUN
cusj-5649	191	47	of	of	ADP
cusj-5649	191	48	cd155	cd155	PROPN
cusj-5649	191	49	)	)	PUNCT
cusj-5649	191	50	that	that	SCONJ
cusj-5649	191	51	the	the	DET
cusj-5649	191	52	antibody	antibody	NOUN
cusj-5649	191	53	did	do	AUX
cusj-5649	191	54	recognize	recognize	VERB
cusj-5649	191	55	the	the	DET
cusj-5649	191	56	figure	figure	NOUN
cusj-5649	191	57	1	1	NUM
cusj-5649	191	58	c6	c6	PROPN
cusj-5649	191	59	control	control	NOUN
cusj-5649	191	60	cells	cell	NOUN
cusj-5649	191	61	remaining	remain	VERB
cusj-5649	191	62	on	on	ADP
cusj-5649	191	63	top	top	NOUN
cusj-5649	191	64	of	of	ADP
cusj-5649	191	65	the	the	DET
cusj-5649	191	66	äs[ly	äs[ly	PROPN
cusj-5649	191	67	�	�	PROPN
cusj-5649	191	68	hm[ly	hm[ly	PROPN
cusj-5649	191	69	�	�	PROPN
cusj-5649	191	70	h	h	PROPN
cusj-5649	191	71	�	�	PROPN
cusj-5649	191	72	�	�	PROPN
cusj-5649	191	73	�	�	PROPN
cusj-5649	191	74	�	�	PROPN
cusj-5649	191	75	�	�	PROPN
cusj-5649	191	76	ov\y	ov\y	NOUN
cusj-5649	191	77	�	�	PROPN
cusj-5649	191	78	tpnyh[pvu	tpnyh[pvu	PROPN
cusj-5649	191	79	�	�	PROPN
cusj-5649	191	80	wlypvk	wlypvk	PROPN
cusj-5649	191	81	�	�	PROPN
cusj-5649	191	82	c6	c6	PROPN
cusj-5649	191	83	control	control	NOUN
cusj-5649	191	84	cells	cell	NOUN
cusj-5649	191	85	at	at	ADP
cusj-5649	191	86	the	the	DET
cusj-5649	191	87	bottom	bottom	NOUN
cusj-5649	191	88	of	of	ADP
cusj-5649	191	89	äs[ly	äs[ly	PROPN
cusj-5649	191	90	�	�	PROPN
cusj-5649	191	91	hm[ly	hm[ly	PROPN
cusj-5649	191	92	�	�	PROPN
cusj-5649	191	93	�	�	PROPN
cusj-5649	191	94	�	�	PROPN
cusj-5649	191	95	�	�	PROPN
cusj-5649	191	96	�	�	PROPN
cusj-5649	191	97	ov\y	ov\y	NOUN
cusj-5649	191	98	�	�	PROPN
cusj-5649	191	99	tpnyh[pvu	tpnyh[pvu	PROPN
cusj-5649	191	100	�	�	PROPN
cusj-5649	191	101	wlypvk	wlypvk	PROPN
cusj-5649	191	102	�	�	PROPN
cusj-5649	191	103	�	�	PROPN
cusj-5649	191	104	figure	figure	NOUN
cusj-5649	191	105	2	2	NUM
cusj-5649	191	106	pvr	pvr	NOUN
cusj-5649	191	107	-	-	PUNCT
cusj-5649	191	108	transfected	transfecte	VERB
cusj-5649	191	109	cells	cell	NOUN
cusj-5649	191	110	at	at	ADP
cusj-5649	191	111	the	the	DET
cusj-5649	191	112	bottom	bottom	NOUN
cusj-5649	191	113	of	of	ADP
cusj-5649	191	114	äs[ly	äs[ly	PROPN
cusj-5649	191	115	�	�	PROPN
cusj-5649	191	116	hm[ly	hm[ly	PROPN
cusj-5649	191	117	�	�	PROPN
cusj-5649	191	118	�	�	PROPN
cusj-5649	191	119	�	�	PROPN
cusj-5649	191	120	�	�	PROPN
cusj-5649	191	121	�	�	PROPN
cusj-5649	191	122	ov\y	ov\y	NOUN
cusj-5649	191	123	�	�	PROPN
cusj-5649	191	124	tpnyh[pvu	tpnyh[pvu	PROPN
cusj-5649	191	125	�	�	PROPN
cusj-5649	191	126	wlypvk	wlypvk	PROPN
cusj-5649	191	127	�	�	PROPN
cusj-5649	191	128	figure	figure	VERB
cusj-5649	191	129	3	3	NUM
cusj-5649	191	130	figure	figure	NOUN
cusj-5649	191	131	4	4	NUM
cusj-5649	191	132	migrating	migrate	VERB
cusj-5649	191	133	c6	c6	PROPN
cusj-5649	191	134	cells	cell	NOUN
cusj-5649	191	135	:	:	PUNCT
cusj-5649	191	136	control	control	NOUN
cusj-5649	191	137	vs	vs	ADP
cusj-5649	191	138	transfection	transfection	NOUN
cusj-5649	191	139	with	with	ADP
cusj-5649	191	140	pvr	pvr	NOUN
cusj-5649	191	141	expression	expression	NOUN
cusj-5649	191	142	vector	vector	PROPN
cusj-5649	191	143	avg	avg	PROPN
cusj-5649	191	144	.	.	PROPN
cusj-5649	192	1	of	of	ADP
cusj-5649	192	2	assay	assay	PROPN
cusj-5649	192	3	1	1	NUM
cusj-5649	192	4	control	control	NOUN
cusj-5649	192	5	:	:	PUNCT
cusj-5649	192	6	335	335	NUM
cusj-5649	192	7	tfect	tfect	NOUN
cusj-5649	192	8	:	:	PUNCT
cusj-5649	192	9	347	347	NUM
cusj-5649	192	10	avg	avg	NOUN
cusj-5649	192	11	percent	percent	NOUN
cusj-5649	192	12	increase	increase	NOUN
cusj-5649	192	13	:	:	PUNCT
cusj-5649	192	14	3.5	3.5	NUM
cusj-5649	192	15	%	%	NOUN
cusj-5649	192	16	avg	avg	NOUN
cusj-5649	192	17	of	of	ADP
cusj-5649	192	18	assay	assay	PROPN
cusj-5649	192	19	2	2	NUM
cusj-5649	192	20	control	control	NOUN
cusj-5649	192	21	:	:	PUNCT
cusj-5649	192	22	273.5	273.5	NUM
cusj-5649	192	23	tfect	tfect	NOUN
cusj-5649	192	24	:	:	PUNCT
cusj-5649	192	25	362	362	NUM
cusj-5649	192	26	avg	avg	NOUN
cusj-5649	192	27	percent	percent	NOUN
cusj-5649	192	28	increase	increase	NOUN
cusj-5649	192	29	:	:	PUNCT
cusj-5649	192	30	32.4	32.4	NUM
cusj-5649	192	31	%	%	NOUN
cusj-5649	192	32	avg	avg	NOUN
cusj-5649	192	33	of	of	ADP
cusj-5649	192	34	all	all	DET
cusj-5649	192	35	control	control	NOUN
cusj-5649	192	36	:	:	PUNCT
cusj-5649	192	37	304.25	304.25	NUM
cusj-5649	192	38	tfect	tfect	NOUN
cusj-5649	192	39	:	:	PUNCT
cusj-5649	192	40	354.5	354.5	NUM
cusj-5649	192	41	avg	avg	NOUN
cusj-5649	192	42	percent	percent	NOUN
cusj-5649	192	43	increase	increase	NOUN
cusj-5649	192	44	:	:	PUNCT
cusj-5649	192	45	16.5	16.5	NUM
cusj-5649	192	46	%	%	NOUN
cusj-5649	192	47	two	two	NUM
cusj-5649	192	48	-	-	PUNCT
cusj-5649	192	49	tailed	tail	VERB
cusj-5649	192	50	p	p	NOUN
cusj-5649	192	51	value	value	NOUN
cusj-5649	192	52	=	=	SYM
cusj-5649	192	53	0.0957	0.0957	NUM
cusj-5649	192	54	image	image	NOUN
cusj-5649	192	55	content	content	NOUN
cusj-5649	192	56	dna	dna	PROPN
cusj-5649	192	57	absorbance	absorbance	NOUN
cusj-5649	192	58	(	(	PUNCT
cusj-5649	192	59	µg	µg	NOUN
cusj-5649	192	60	/	/	SYM
cusj-5649	192	61	ul	ul	NOUN
cusj-5649	192	62	)	)	PUNCT
cusj-5649	192	63	nuclei	nucleus	NOUN
cusj-5649	192	64	count	count	VERB
cusj-5649	192	65	_	_	PUNCT
cusj-5649	193	1	_	_	PUNCT
cusj-5649	194	1	_	_	PUNCT
cusj-5649	195	1	_	_	PUNCT
cusj-5649	196	1	_	_	PUNCT
cusj-5649	197	1	_	_	PUNCT
cusj-5649	198	1	_	_	PUNCT
cusj-5649	199	1	_	_	PUNCT
cusj-5649	200	1	_	_	PUNCT
cusj-5649	201	1	_	_	PUNCT
cusj-5649	202	1	_	_	PUNCT
cusj-5649	203	1	_	_	PUNCT
cusj-5649	204	1	_	_	PUNCT
cusj-5649	205	1	_	_	PUNCT
cusj-5649	206	1	_	_	PUNCT
cusj-5649	207	1	_	_	PUNCT
cusj-5649	208	1	_	_	PUNCT
cusj-5649	209	1	_	_	PUNCT
cusj-5649	210	1	_	_	PUNCT
cusj-5649	211	1	_	_	PUNCT
cusj-5649	212	1	_	_	PUNCT
cusj-5649	213	1	_	_	PUNCT
cusj-5649	214	1	_	_	PUNCT
cusj-5649	215	1	_	_	PUNCT
cusj-5649	216	1	_	_	PUNCT
cusj-5649	217	1	_	_	PUNCT
cusj-5649	218	1	_	_	PUNCT
cusj-5649	219	1	_	_	PUNCT
cusj-5649	220	1	_	_	PUNCT
cusj-5649	221	1	_	_	PUNCT
cusj-5649	222	1	_	_	PUNCT
cusj-5649	223	1	_	_	PUNCT
cusj-5649	224	1	_	_	PUNCT
cusj-5649	225	1	_	_	PUNCT
cusj-5649	226	1	_	_	PUNCT
cusj-5649	227	1	_	_	PUNCT
cusj-5649	228	1	_	_	PUNCT
cusj-5649	229	1	_	_	PUNCT
cusj-5649	230	1	_	_	PUNCT
cusj-5649	231	1	_	_	PUNCT
cusj-5649	232	1	_	_	PUNCT
cusj-5649	233	1	_	_	PUNCT
cusj-5649	234	1	_	_	PUNCT
cusj-5649	235	1	_	_	PUNCT
cusj-5649	236	1	_	_	PUNCT
cusj-5649	237	1	_	_	PUNCT
cusj-5649	238	1	_	_	PUNCT
cusj-5649	239	1	_	_	PUNCT
cusj-5649	240	1	_	_	PUNCT
cusj-5649	241	1	_	_	PUNCT
cusj-5649	242	1	_	_	PUNCT
cusj-5649	243	1	_	_	PUNCT
cusj-5649	244	1	_	_	PUNCT
cusj-5649	245	1	_	_	PUNCT
cusj-5649	246	1	_	_	PUNCT
cusj-5649	247	1	_	_	PUNCT
cusj-5649	248	1	_	_	PUNCT
cusj-5649	249	1	_	_	PUNCT
cusj-5649	250	1	_	_	PUNCT
cusj-5649	251	1	_	_	PUNCT
cusj-5649	252	1	_	_	PUNCT
cusj-5649	253	1	_	_	PUNCT
cusj-5649	254	1	_	_	PUNCT
cusj-5649	255	1	_	_	PUNCT
cusj-5649	256	1	_	_	PUNCT
cusj-5649	257	1	_	_	PUNCT
cusj-5649	258	1	_	_	PUNCT
cusj-5649	259	1	_	_	PUNCT
cusj-5649	260	1	_	_	PUNCT
cusj-5649	261	1	_	_	PUNCT
cusj-5649	261	2	_	_	PUNCT
cusj-5649	262	1	_	_	PUNCT
cusj-5649	263	1	control	control	NOUN
cusj-5649	263	2	1a	1a	PROPN
cusj-5649	263	3	315	315	NUM
cusj-5649	263	4	control	control	NOUN
cusj-5649	263	5	1b	1b	NUM
cusj-5649	263	6	355	355	NUM
cusj-5649	263	7	control	control	NOUN
cusj-5649	263	8	2a	2a	NUM
cusj-5649	263	9	260	260	NUM
cusj-5649	263	10	control	control	NOUN
cusj-5649	263	11	2b	2b	NUM
cusj-5649	263	12	287	287	NUM
cusj-5649	263	13	tfect	tfect	NOUN
cusj-5649	263	14	1a	1a	NOUN
cusj-5649	263	15	.3	.3	NUM
cusj-5649	263	16	327	327	NUM
cusj-5649	263	17	tfect	tfect	NOUN
cusj-5649	263	18	1b	1b	NUM
cusj-5649	263	19	.3	.3	NUM
cusj-5649	263	20	367	367	NUM
cusj-5649	263	21	tfect	tfect	PROPN
cusj-5649	263	22	2a	2a	NUM
cusj-5649	263	23	.4	.4	NUM
cusj-5649	263	24	332	332	NUM
cusj-5649	263	25	tfect	tfect	NOUN
cusj-5649	263	26	2b	2b	NOUN
cusj-5649	263	27	.4	.4	NUM
cusj-5649	263	28	392	392	NUM
cusj-5649	263	29	results	result	NOUN
cusj-5649	263	30	columbia	columbia	PROPN
cusj-5649	263	31	undergraduate	undergraduate	PROPN
cusj-5649	263	32	science	science	PROPN
cusj-5649	263	33	journal	journal	PROPN
cusj-5649	263	34	open	open	ADJ
cusj-5649	263	35	-	-	PUNCT
cusj-5649	263	36	access	access	NOUN
cusj-5649	263	37	publication	publication	NOUN
cusj-5649	263	38	|	|	ADV
cusj-5649	263	39	http://cusj.columbia.com	http://cusj.columbia.com	X
cusj-5649	263	40	48	48	NUM
cusj-5649	263	41	cusjvolume	cusjvolume	ADJ
cusj-5649	264	1	5spring	5spring	NUM
cusj-5649	264	2	2011	2011	NUM
cusj-5649	264	3	columbia	columbia	PROPN
cusj-5649	264	4	undergraduate	undergraduate	NOUN
cusj-5649	264	5	sci	sci	PROPN
cusj-5649	264	6	j	j	PROPN
cusj-5649	264	7	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	264	8	v	v	ADP
cusj-5649	264	9	ir	ir	PROPN
cusj-5649	264	10	o	o	NOUN
cusj-5649	265	1	lo	lo	NOUN
cusj-5649	265	2	g	g	PROPN
cusj-5649	265	3	y	y	PROPN
cusj-5649	265	4	cusjcolumbia	cusjcolumbia	ADJ
cusj-5649	265	5	undergraduate	undergraduate	NOUN
cusj-5649	265	6	science	science	NOUN
cusj-5649	265	7	journalresearch	journalresearch	NOUN
cusj-5649	265	8	articles	article	VERB
cusj-5649	265	9	49cusj	49cusj	NUM
cusj-5649	265	10	volume	volume	NOUN
cusj-5649	265	11	5spring	5spring	PROPN
cusj-5649	265	12	2011	2011	NUM
cusj-5649	265	13	columbia	columbia	PROPN
cusj-5649	265	14	undergraduate	undergraduate	NOUN
cusj-5649	265	15	sci	sci	PROPN
cusj-5649	265	16	j	j	PROPN
cusj-5649	265	17	http://cusj.columbia.edu	http://cusj.columbia.edu	PROPN
cusj-5649	265	18	v	v	ADP
cusj-5649	265	19	ir	ir	PROPN
cusj-5649	266	1	o	o	NOUN
cusj-5649	267	1	lo	lo	NOUN
cusj-5649	268	1	g	g	PROPN
cusj-5649	268	2	y	y	PROPN
cusj-5649	268	3	human	human	ADJ
cusj-5649	268	4	protein	protein	NOUN
cusj-5649	268	5	and	and	CCONJ
cusj-5649	268	6	that	that	SCONJ
cusj-5649	268	7	it	it	PRON
cusj-5649	268	8	is	be	AUX
cusj-5649	268	9	in	in	ADP
cusj-5649	268	10	fact	fact	NOUN
cusj-5649	268	11	present	present	ADJ
cusj-5649	268	12	in	in	ADP
cusj-5649	268	13	the	the	DET
cusj-5649	268	14	cells	cell	NOUN
cusj-5649	268	15	.	.	PUNCT
cusj-5649	269	1	because	because	SCONJ
cusj-5649	269	2	the	the	DET
cusj-5649	269	3	band	band	NOUN
cusj-5649	269	4	on	on	ADP
cusj-5649	269	5	the	the	DET
cusj-5649	269	6	right	right	NOUN
cusj-5649	269	7	,	,	PUNCT
cusj-5649	269	8	the	the	DET
cusj-5649	269	9	transfected	transfecte	VERB
cusj-5649	269	10	band	band	NOUN
cusj-5649	269	11	,	,	PUNCT
cusj-5649	269	12	is	be	AUX
cusj-5649	269	13	so	so	ADV
cusj-5649	269	14	much	much	ADV
cusj-5649	269	15	darker	dark	ADJ
cusj-5649	269	16	,	,	PUNCT
cusj-5649	269	17	we	we	PRON
cusj-5649	269	18	can	can	AUX
cusj-5649	269	19	also	also	ADV
cusj-5649	269	20	assume	assume	VERB
cusj-5649	269	21	that	that	SCONJ
cusj-5649	269	22	our	our	PRON
cusj-5649	269	23	over	over	NOUN
cusj-5649	269	24	-	-	PUNCT
cusj-5649	269	25	expression	expression	NOUN
cusj-5649	269	26	last	last	ADJ
cusj-5649	269	27	term	term	NOUN
cusj-5649	269	28	was	be	AUX
cusj-5649	269	29	successful	successful	ADJ
cusj-5649	269	30	and	and	CCONJ
cusj-5649	269	31	that	that	SCONJ
cusj-5649	269	32	any	any	DET
cusj-5649	269	33	impact	impact	NOUN
cusj-5649	269	34	on	on	ADP
cusj-5649	269	35	migration	migration	NOUN
cusj-5649	269	36	we	we	PRON
cusj-5649	269	37	saw	see	VERB
cusj-5649	269	38	was	be	AUX
cusj-5649	269	39	directly	directly	ADV
cusj-5649	269	40	correlated	correlate	VERB
cusj-5649	269	41	to	to	ADP
cusj-5649	269	42	the	the	DET
cusj-5649	269	43	up	up	NOUN
cusj-5649	269	44	-	-	PUNCT
cusj-5649	269	45	regulation	regulation	NOUN
cusj-5649	269	46	of	of	ADP
cusj-5649	269	47	cd155	cd155	PROPN
cusj-5649	269	48	in	in	ADP
cusj-5649	269	49	the	the	DET
cusj-5649	269	50	c6	c6	PROPN
cusj-5649	269	51	cells	cell	NOUN
cusj-5649	269	52	(	(	PUNCT
cusj-5649	269	53	figure	figure	NOUN
cusj-5649	269	54	5	5	NUM
cusj-5649	269	55	)	)	PUNCT
cusj-5649	269	56	.	.	PUNCT
cusj-5649	270	1	in	in	ADP
cusj-5649	270	2	the	the	DET
cusj-5649	270	3	second	second	ADJ
cusj-5649	270	4	western	western	ADJ
cusj-5649	270	5	blot	blot	NOUN
cusj-5649	270	6	,	,	PUNCT
cusj-5649	270	7	which	which	PRON
cusj-5649	270	8	compared	compare	VERB
cusj-5649	270	9	c6	c6	PROPN
cusj-5649	270	10	and	and	CCONJ
cusj-5649	270	11	u87	u87	ADJ
cusj-5649	270	12	control	control	NOUN
cusj-5649	270	13	glioma	glioma	NOUN
cusj-5649	270	14	cells	cell	NOUN
cusj-5649	270	15	,	,	PUNCT
cusj-5649	270	16	we	we	PRON
cusj-5649	270	17	can	can	AUX
cusj-5649	270	18	observe	observe	VERB
cusj-5649	270	19	two	two	NUM
cusj-5649	270	20	distinct	distinct	ADJ
cusj-5649	270	21	,	,	PUNCT
cusj-5649	270	22	dark	dark	ADJ
cusj-5649	270	23	bands	band	NOUN
cusj-5649	270	24	(	(	PUNCT
cusj-5649	270	25	again	again	ADV
cusj-5649	270	26	located	locate	VERB
cusj-5649	270	27	around	around	ADV
cusj-5649	270	28	40	40	NUM
cusj-5649	270	29	kda	kda	NOUN
cusj-5649	270	30	)	)	PUNCT
cusj-5649	270	31	(	(	PUNCT
cusj-5649	270	32	figure	figure	NOUN
cusj-5649	270	33	6	6	NUM
cusj-5649	270	34	)	)	PUNCT
cusj-5649	270	35	.	.	PUNCT
cusj-5649	270	36	!	!	PUNCT
cusj-5649	271	1	is	be	AUX
cusj-5649	271	2	is	be	AUX
cusj-5649	271	3	a	a	DET
cusj-5649	271	4	strong	strong	ADJ
cusj-5649	271	5	indication	indication	NOUN
cusj-5649	271	6	that	that	SCONJ
cusj-5649	271	7	both	both	CCONJ
cusj-5649	271	8	c6	c6	NOUN
cusj-5649	271	9	and	and	CCONJ
cusj-5649	271	10	u87	u87	ADJ
cusj-5649	271	11	glioma	glioma	NOUN
cusj-5649	271	12	cells	cell	NOUN
cusj-5649	271	13	naturally	naturally	ADV
cusj-5649	271	14	contain	contain	VERB
cusj-5649	271	15	comparable	comparable	ADJ
cusj-5649	271	16	and	and	CCONJ
cusj-5649	271	17	substantial	substantial	ADJ
cusj-5649	271	18	levels	level	NOUN
cusj-5649	271	19	of	of	ADP
cusj-5649	271	20	cd155	cd155	NOUN
cusj-5649	271	21	protein	protein	NOUN
cusj-5649	271	22	.	.	PUNCT
cusj-5649	272	1	we	we	PRON
cusj-5649	272	2	were	be	AUX
cusj-5649	272	3	attempting	attempt	VERB
cusj-5649	272	4	to	to	PART
cusj-5649	272	5	mirror	mirror	VERB
cusj-5649	272	6	the	the	DET
cusj-5649	272	7	results	result	NOUN
cusj-5649	272	8	of	of	ADP
cusj-5649	272	9	a	a	DET
cusj-5649	272	10	reputable	reputable	ADJ
cusj-5649	272	11	knockdown	knockdown	NOUN
cusj-5649	272	12	study	study	NOUN
cusj-5649	272	13	conducted	conduct	VERB
cusj-5649	272	14	by	by	ADP
cusj-5649	272	15	the	the	DET
cusj-5649	272	16	department	department	PROPN
cusj-5649	272	17	of	of	ADP
cusj-5649	272	18	physiology	physiology	NOUN
cusj-5649	272	19	at	at	ADP
cusj-5649	272	20	tufts	tuft	NOUN
cusj-5649	272	21	university	university	NOUN
cusj-5649	272	22	school	school	NOUN
cusj-5649	272	23	of	of	ADP
cusj-5649	272	24	medicine	medicine	NOUN
cusj-5649	272	25	,	,	PUNCT
cusj-5649	272	26	(	(	PUNCT
cusj-5649	272	27	boston	boston	PROPN
cusj-5649	272	28	,	,	PUNCT
cusj-5649	272	29	massachusetts	massachusetts	PROPN
cusj-5649	272	30	)	)	PUNCT
cusj-5649	272	31	and	and	CCONJ
cusj-5649	272	32	the	the	DET
cusj-5649	272	33	department	department	NOUN
cusj-5649	272	34	of	of	ADP
cusj-5649	272	35	neurobiology	neurobiology	NOUN
cusj-5649	272	36	at	at	ADP
cusj-5649	272	37	yale	yale	PROPN
cusj-5649	272	38	university	university	PROPN
cusj-5649	272	39	school	school	NOUN
cusj-5649	272	40	of	of	ADP
cusj-5649	272	41	medicine	medicine	NOUN
cusj-5649	272	42	(	(	PUNCT
cusj-5649	272	43	new	new	ADJ
cusj-5649	272	44	haven	haven	NOUN
cusj-5649	272	45	,	,	PUNCT
cusj-5649	272	46	connecticut	connecticut	PROPN
cusj-5649	272	47	)	)	PUNCT
cusj-5649	272	48	.	.	PUNCT
cusj-5649	272	49	!	!	PUNCT
cusj-5649	273	1	is	be	AUX
cusj-5649	273	2	study	study	NOUN
cusj-5649	273	3	showed	show	VERB
cusj-5649	273	4	that	that	SCONJ
cusj-5649	273	5	a	a	DET
cusj-5649	273	6	knockdown	knockdown	NOUN
cusj-5649	273	7	of	of	ADP
cusj-5649	273	8	cd155	cd155	NOUN
cusj-5649	273	9	by	by	ADP
cusj-5649	273	10	fali	fali	PROPN
cusj-5649	273	11	in	in	ADP
cusj-5649	273	12	u87	u87	NOUN
cusj-5649	273	13	mg	mg	PROPN
cusj-5649	273	14	cells	cell	NOUN
cusj-5649	273	15	resulted	result	VERB
cusj-5649	273	16	in	in	ADP
cusj-5649	273	17	a	a	DET
cusj-5649	273	18	signi"cant	signi"cant	NOUN
cusj-5649	273	19	(	(	PUNCT
cusj-5649	273	20	16	16	NUM
cusj-5649	273	21	to	to	PART
cusj-5649	273	22	22	22	NUM
cusj-5649	273	23	%	%	NOUN
cusj-5649	273	24	)	)	PUNCT
cusj-5649	273	25	decrease	decrease	NOUN
cusj-5649	273	26	in	in	ADP
cusj-5649	273	27	trans	trans	ADJ
cusj-5649	273	28	-	-	ADJ
cusj-5649	273	29	well	well	ADJ
cusj-5649	273	30	migration	migration	NOUN
cusj-5649	273	31	(	(	PUNCT
cusj-5649	273	32	sloan	sloan	NOUN
cusj-5649	273	33	,	,	PUNCT
cusj-5649	273	34	2005	2005	NUM
cusj-5649	273	35	)	)	PUNCT
cusj-5649	273	36	.	.	PUNCT
cusj-5649	274	1	because	because	SCONJ
cusj-5649	274	2	the	the	DET
cusj-5649	274	3	sirna	sirna	PROPN
cusj-5649	274	4	expression	expression	NOUN
cusj-5649	274	5	vector	vector	NOUN
cusj-5649	274	6	was	be	AUX
cusj-5649	274	7	not	not	PART
cusj-5649	274	8	available	available	ADJ
cusj-5649	274	9	to	to	PART
cusj-5649	274	10	conduct	conduct	VERB
cusj-5649	274	11	a	a	DET
cusj-5649	274	12	knockdown	knockdown	NOUN
cusj-5649	274	13	experiment	experiment	NOUN
cusj-5649	274	14	,	,	PUNCT
cusj-5649	274	15	our	our	PRON
cusj-5649	274	16	study	study	NOUN
cusj-5649	274	17	would	would	AUX
cusj-5649	274	18	be	be	AUX
cusj-5649	274	19	used	use	VERB
cusj-5649	274	20	to	to	PART
cusj-5649	274	21	perhaps	perhaps	ADV
cusj-5649	274	22	mirror	mirror	VERB
cusj-5649	274	23	the	the	DET
cusj-5649	274	24	relationship	relationship	NOUN
cusj-5649	274	25	that	that	PRON
cusj-5649	274	26	has	have	AUX
cusj-5649	274	27	been	be	AUX
cusj-5649	274	28	found	find	VERB
cusj-5649	274	29	previously	previously	ADV
cusj-5649	274	30	in	in	ADP
cusj-5649	274	31	the	the	DET
cusj-5649	274	32	knockdown	knockdown	NOUN
cusj-5649	274	33	of	of	ADP
cusj-5649	274	34	cd155	cd155	PROPN
cusj-5649	274	35	.	.	PUNCT
cusj-5649	275	1	we	we	PRON
cusj-5649	275	2	expected	expect	VERB
cusj-5649	275	3	that	that	SCONJ
cusj-5649	275	4	over	over	NOUN
cusj-5649	275	5	-	-	PUNCT
cusj-5649	275	6	expression	expression	NOUN
cusj-5649	275	7	of	of	ADP
cusj-5649	275	8	cd155	cd155	PROPN
cusj-5649	275	9	would	would	AUX
cusj-5649	275	10	signi"cantly	signi"cantly	ADV
cusj-5649	275	11	increase	increase	VERB
cusj-5649	275	12	migration	migration	NOUN
cusj-5649	275	13	based	base	VERB
cusj-5649	275	14	on	on	ADP
cusj-5649	275	15	the	the	DET
cusj-5649	275	16	expression	expression	NOUN
cusj-5649	275	17	of	of	ADP
cusj-5649	275	18	protein	protein	NOUN
cusj-5649	275	19	levels	level	NOUN
cusj-5649	275	20	indicated	indicate	VERB
cusj-5649	275	21	by	by	ADP
cusj-5649	275	22	western	western	ADJ
cusj-5649	275	23	blot	blot	NOUN
cusj-5649	275	24	analysis	analysis	NOUN
cusj-5649	275	25	.	.	PUNCT
cusj-5649	276	1	if	if	SCONJ
cusj-5649	276	2	the	the	DET
cusj-5649	276	3	over	over	NOUN
cusj-5649	276	4	-	-	PUNCT
cusj-5649	276	5	expression	expression	NOUN
cusj-5649	276	6	were	be	AUX
cusj-5649	276	7	successful	successful	ADJ
cusj-5649	276	8	,	,	PUNCT
cusj-5649	276	9	we	we	PRON
cusj-5649	276	10	would	would	AUX
cusj-5649	276	11	expect	expect	VERB
cusj-5649	276	12	that	that	SCONJ
cusj-5649	276	13	the	the	DET
cusj-5649	276	14	knockdown	knockdown	NOUN
cusj-5649	276	15	that	that	PRON
cusj-5649	276	16	we	we	PRON
cusj-5649	276	17	were	be	AUX
cusj-5649	276	18	unable	unable	ADJ
cusj-5649	276	19	to	to	PART
cusj-5649	276	20	conduct	conduct	VERB
cusj-5649	276	21	out	out	ADP
cusj-5649	276	22	of	of	ADP
cusj-5649	276	23	lack	lack	NOUN
cusj-5649	276	24	of	of	ADP
cusj-5649	276	25	a	a	DET
cusj-5649	276	26	rnai	rnai	NOUN
cusj-5649	276	27	expression	expression	NOUN
cusj-5649	276	28	vector	vector	NOUN
cusj-5649	276	29	would	would	AUX
cusj-5649	276	30	also	also	ADV
cusj-5649	276	31	decrease	decrease	VERB
cusj-5649	276	32	migration	migration	NOUN
cusj-5649	276	33	.	.	PUNCT
cusj-5649	277	1	despite	despite	SCONJ
cusj-5649	277	2	our	our	PRON
cusj-5649	277	3	predictions	prediction	NOUN
cusj-5649	277	4	earlier	early	ADV
cusj-5649	277	5	in	in	ADP
cusj-5649	277	6	the	the	DET
cusj-5649	277	7	year	year	NOUN
cusj-5649	277	8	,	,	PUNCT
cusj-5649	277	9	there	there	PRON
cusj-5649	277	10	did	do	AUX
cusj-5649	277	11	not	not	PART
cusj-5649	277	12	appear	appear	VERB
cusj-5649	277	13	to	to	PART
cusj-5649	277	14	be	be	AUX
cusj-5649	277	15	a	a	DET
cusj-5649	277	16	tangible	tangible	ADJ
cusj-5649	277	17	visible	visible	ADJ
cusj-5649	277	18	di#erence	di#erence	NOUN
cusj-5649	277	19	between	between	ADP
cusj-5649	277	20	the	the	DET
cusj-5649	277	21	control	control	NOUN
cusj-5649	277	22	pictures	picture	NOUN
cusj-5649	277	23	and	and	CCONJ
cusj-5649	277	24	the	the	DET
cusj-5649	277	25	transfected	transfecte	VERB
cusj-5649	277	26	pictures	picture	NOUN
cusj-5649	277	27	for	for	ADP
cusj-5649	277	28	this	this	DET
cusj-5649	277	29	experiment	experiment	NOUN
cusj-5649	277	30	as	as	ADP
cusj-5649	277	31	a	a	DET
cusj-5649	277	32	whole	whole	NOUN
cusj-5649	277	33	.	.	PUNCT
cusj-5649	278	1	one	one	PRON
cusj-5649	278	2	may	may	AUX
cusj-5649	278	3	notice	notice	VERB
cusj-5649	278	4	that	that	SCONJ
cusj-5649	278	5	in	in	ADP
cusj-5649	278	6	general	general	ADJ
cusj-5649	278	7	the	the	DET
cusj-5649	278	8	transfected	transfecte	VERB
cusj-5649	278	9	cell	cell	NOUN
cusj-5649	278	10	"	"	PUNCT
cusj-5649	278	11	elds	eld	NOUN
cusj-5649	278	12	were	be	AUX
cusj-5649	278	13	clearer	clear	ADJ
cusj-5649	278	14	,	,	PUNCT
cusj-5649	278	15	and	and	CCONJ
cusj-5649	278	16	that	that	SCONJ
cusj-5649	278	17	the	the	DET
cusj-5649	278	18	control	control	NOUN
cusj-5649	278	19	"	"	PUNCT
cusj-5649	278	20	elds	eld	NOUN
cusj-5649	278	21	contained	contain	VERB
cusj-5649	278	22	a	a	DET
cusj-5649	278	23	lot	lot	NOUN
cusj-5649	278	24	of	of	ADP
cusj-5649	278	25	processes	process	NOUN
cusj-5649	278	26	(	(	PUNCT
cusj-5649	278	27	especially	especially	ADV
cusj-5649	278	28	in	in	ADP
cusj-5649	278	29	trans"lter	trans"lt	ADJ
cusj-5649	278	30	assay	assay	NOUN
cusj-5649	278	31	1	1	NUM
cusj-5649	278	32	)	)	PUNCT
cusj-5649	278	33	(	(	PUNCT
cusj-5649	278	34	figure	figure	NOUN
cusj-5649	278	35	3	3	NUM
cusj-5649	278	36	)	)	PUNCT
cusj-5649	278	37	.	.	PUNCT
cusj-5649	278	38	!	!	PUNCT
cusj-5649	279	1	is	be	AUX
cusj-5649	279	2	could	could	AUX
cusj-5649	279	3	be	be	AUX
cusj-5649	279	4	possibly	possibly	ADV
cusj-5649	279	5	interpreted	interpret	VERB
cusj-5649	279	6	as	as	ADP
cusj-5649	279	7	the	the	DET
cusj-5649	279	8	presence	presence	NOUN
cusj-5649	279	9	of	of	ADP
cusj-5649	279	10	cd155	cd155	NOUN
cusj-5649	279	11	speeding	speeding	NOUN
cusj-5649	279	12	up	up	ADP
cusj-5649	279	13	the	the	DET
cusj-5649	279	14	growth	growth	NOUN
cusj-5649	279	15	of	of	ADP
cusj-5649	279	16	cells	cell	NOUN
cusj-5649	279	17	.	.	PUNCT
cusj-5649	280	1	if	if	SCONJ
cusj-5649	280	2	a	a	DET
cusj-5649	280	3	knockdown	knockdown	NOUN
cusj-5649	280	4	in	in	ADP
cusj-5649	280	5	u87	u87	ADJ
cusj-5649	280	6	glioma	glioma	NOUN
cusj-5649	280	7	decreased	decrease	VERB
cusj-5649	280	8	migration	migration	NOUN
cusj-5649	280	9	of	of	ADP
cusj-5649	280	10	cells	cell	NOUN
cusj-5649	280	11	,	,	PUNCT
cusj-5649	280	12	we	we	PRON
cusj-5649	280	13	could	could	AUX
cusj-5649	280	14	infer	infer	VERB
cusj-5649	280	15	that	that	SCONJ
cusj-5649	280	16	cd155	cd155	PROPN
cusj-5649	280	17	possibly	possibly	ADV
cusj-5649	280	18	enhances	enhance	VERB
cusj-5649	280	19	the	the	DET
cusj-5649	280	20	tumor	tumor	NOUN
cusj-5649	280	21	and	and	CCONJ
cusj-5649	280	22	may	may	AUX
cusj-5649	280	23	serve	serve	VERB
cusj-5649	280	24	as	as	ADP
cusj-5649	280	25	a	a	DET
cusj-5649	280	26	catalyst	catalyst	NOUN
cusj-5649	280	27	for	for	ADP
cusj-5649	280	28	tumor	tumor	NOUN
cusj-5649	280	29	growth	growth	NOUN
cusj-5649	280	30	.	.	PUNCT
cusj-5649	281	1	cd155	cd155	PROPN
cusj-5649	281	2	does	do	AUX
cusj-5649	281	3	not	not	PART
cusj-5649	281	4	appear	appear	VERB
cusj-5649	281	5	to	to	PART
cusj-5649	281	6	a#ect	a#ect	VERB
cusj-5649	281	7	the	the	DET
cusj-5649	281	8	shape	shape	NOUN
cusj-5649	281	9	or	or	CCONJ
cusj-5649	281	10	size	size	NOUN
cusj-5649	281	11	of	of	ADP
cusj-5649	281	12	the	the	DET
cusj-5649	281	13	cells	cell	NOUN
cusj-5649	281	14	.	.	PUNCT
cusj-5649	282	1	without	without	ADP
cusj-5649	282	2	the	the	DET
cusj-5649	282	3	western	western	ADJ
cusj-5649	282	4	blots	blot	NOUN
cusj-5649	282	5	,	,	PUNCT
cusj-5649	282	6	which	which	PRON
cusj-5649	282	7	were	be	AUX
cusj-5649	282	8	conducted	conduct	VERB
cusj-5649	282	9	towards	towards	ADP
cusj-5649	282	10	the	the	DET
cusj-5649	282	11	end	end	NOUN
cusj-5649	282	12	of	of	ADP
cusj-5649	282	13	our	our	PRON
cusj-5649	282	14	study	study	NOUN
cusj-5649	282	15	,	,	PUNCT
cusj-5649	282	16	we	we	PRON
cusj-5649	282	17	were	be	AUX
cusj-5649	282	18	not	not	PART
cusj-5649	282	19	able	able	ADJ
cusj-5649	282	20	to	to	PART
cusj-5649	282	21	detect	detect	VERB
cusj-5649	282	22	whether	whether	SCONJ
cusj-5649	282	23	or	or	CCONJ
cusj-5649	282	24	not	not	PART
cusj-5649	282	25	the	the	DET
cusj-5649	282	26	transfection	transfection	NOUN
cusj-5649	282	27	substantially	substantially	ADV
cusj-5649	282	28	increased	increase	VERB
cusj-5649	282	29	the	the	DET
cusj-5649	282	30	presence	presence	NOUN
cusj-5649	282	31	of	of	ADP
cusj-5649	282	32	cd155	cd155	PROPN
cusj-5649	282	33	or	or	CCONJ
cusj-5649	282	34	by	by	ADP
cusj-5649	282	35	how	how	SCONJ
cusj-5649	282	36	much	much	ADJ
cusj-5649	282	37	.	.	PUNCT
cusj-5649	282	38	!	!	PUNCT
cusj-5649	283	1	is	be	AUX
cusj-5649	283	2	led	lead	VERB
cusj-5649	283	3	us	we	PRON
cusj-5649	283	4	to	to	PART
cusj-5649	283	5	question	question	VERB
cusj-5649	283	6	whether	whether	SCONJ
cusj-5649	283	7	or	or	CCONJ
cusj-5649	283	8	not	not	PART
cusj-5649	283	9	cd155	cd155	PROPN
cusj-5649	283	10	was	be	AUX
cusj-5649	283	11	actually	actually	ADV
cusj-5649	283	12	present	present	ADJ
cusj-5649	283	13	in	in	ADP
cusj-5649	283	14	c6	c6	PROPN
cusj-5649	283	15	cells	cell	NOUN
cusj-5649	283	16	.	.	PUNCT
cusj-5649	284	1	we	we	PRON
cusj-5649	284	2	supposed	suppose	VERB
cusj-5649	284	3	that	that	SCONJ
cusj-5649	284	4	pursuing	pursue	VERB
cusj-5649	284	5	this	this	DET
cusj-5649	284	6	inquiry	inquiry	NOUN
cusj-5649	284	7	would	would	AUX
cusj-5649	284	8	allow	allow	VERB
cusj-5649	284	9	us	we	PRON
cusj-5649	284	10	to	to	PART
cusj-5649	284	11	make	make	VERB
cusj-5649	284	12	further	further	ADJ
cusj-5649	284	13	distinction	distinction	NOUN
cusj-5649	284	14	between	between	ADP
cusj-5649	284	15	c6	c6	PROPN
cusj-5649	284	16	cells	cell	NOUN
cusj-5649	284	17	and	and	CCONJ
cusj-5649	284	18	human	human	ADJ
cusj-5649	284	19	strain	strain	NOUN
cusj-5649	284	20	glioma	glioma	NOUN
cusj-5649	284	21	.	.	PUNCT
cusj-5649	285	1	at	at	ADP
cusj-5649	285	2	the	the	DET
cusj-5649	285	3	very	very	ADV
cusj-5649	285	4	least	least	ADJ
cusj-5649	285	5	,	,	PUNCT
cusj-5649	285	6	we	we	PRON
cusj-5649	285	7	would	would	AUX
cusj-5649	285	8	"	"	PUNCT
cusj-5649	285	9	nd	nd	ADV
cusj-5649	285	10	our	our	PRON
cusj-5649	285	11	results	result	NOUN
cusj-5649	285	12	to	to	ADP
cusj-5649	285	13	con"rm	con"rm	NOUN
cusj-5649	285	14	an	an	DET
cusj-5649	285	15	expected	expected	ADJ
cusj-5649	285	16	di#erence	di#erence	NOUN
cusj-5649	285	17	between	between	ADP
cusj-5649	285	18	rat	rat	NOUN
cusj-5649	285	19	and	and	CCONJ
cusj-5649	285	20	human	human	ADJ
cusj-5649	285	21	models	model	NOUN
cusj-5649	285	22	.	.	PUNCT
cusj-5649	286	1	we	we	PRON
cusj-5649	286	2	predicted	predict	VERB
cusj-5649	286	3	that	that	SCONJ
cusj-5649	286	4	increased	increase	VERB
cusj-5649	286	5	cd155	cd155	NOUN
cusj-5649	286	6	expression	expression	NOUN
cusj-5649	286	7	in	in	ADP
cusj-5649	286	8	glioma	glioma	NOUN
cusj-5649	286	9	cells	cell	NOUN
cusj-5649	286	10	was	be	AUX
cusj-5649	286	11	important	important	ADJ
cusj-5649	286	12	for	for	ADP
cusj-5649	286	13	migration	migration	NOUN
cusj-5649	286	14	of	of	ADP
cusj-5649	286	15	the	the	DET
cusj-5649	286	16	tumor	tumor	NOUN
cusj-5649	286	17	cells	cell	NOUN
cusj-5649	286	18	in	in	ADP
cusj-5649	286	19	vivo	vivo	NOUN
cusj-5649	286	20	.	.	PUNCT
cusj-5649	287	1	while	while	SCONJ
cusj-5649	287	2	our	our	PRON
cusj-5649	287	3	results	result	NOUN
cusj-5649	287	4	indicate	indicate	VERB
cusj-5649	287	5	promise	promise	NOUN
cusj-5649	287	6	,	,	PUNCT
cusj-5649	287	7	only	only	ADV
cusj-5649	287	8	two	two	NUM
cusj-5649	287	9	successful	successful	ADJ
cusj-5649	287	10	experimental	experimental	ADJ
cusj-5649	287	11	replicates	replicate	NOUN
cusj-5649	287	12	were	be	AUX
cusj-5649	287	13	conducted	conduct	VERB
cusj-5649	287	14	and	and	CCONJ
cusj-5649	287	15	the	the	DET
cusj-5649	287	16	variation	variation	NOUN
cusj-5649	287	17	observed	observe	VERB
cusj-5649	287	18	was	be	AUX
cusj-5649	287	19	large	large	ADJ
cusj-5649	287	20	—	—	PUNCT
cusj-5649	287	21	precluding	preclude	VERB
cusj-5649	287	22	a	a	DET
cusj-5649	287	23	sound	sound	ADJ
cusj-5649	287	24	conclusion	conclusion	NOUN
cusj-5649	287	25	on	on	ADP
cusj-5649	287	26	the	the	DET
cusj-5649	287	27	role	role	NOUN
cusj-5649	287	28	of	of	ADP
cusj-5649	287	29	cd155	cd155	PROPN
cusj-5649	287	30	in	in	ADP
cusj-5649	287	31	migration	migration	NOUN
cusj-5649	287	32	.	.	PUNCT
cusj-5649	288	1	an	an	DET
cusj-5649	288	2	additional	additional	ADJ
cusj-5649	288	3	control	control	NOUN
cusj-5649	288	4	,	,	PUNCT
cusj-5649	288	5	a	a	DET
cusj-5649	288	6	transfection	transfection	NOUN
cusj-5649	288	7	with	with	ADP
cusj-5649	288	8	a	a	DET
cusj-5649	288	9	plasmid	plasmid	NOUN
cusj-5649	288	10	encoding	encode	VERB
cusj-5649	288	11	another	another	DET
cusj-5649	288	12	protein	protein	NOUN
cusj-5649	288	13	,	,	PUNCT
cusj-5649	288	14	would	would	AUX
cusj-5649	288	15	be	be	AUX
cusj-5649	288	16	needed	need	VERB
cusj-5649	288	17	to	to	PART
cusj-5649	288	18	add	add	VERB
cusj-5649	288	19	to	to	ADP
cusj-5649	288	20	future	future	ADJ
cusj-5649	288	21	experiments	experiment	NOUN
cusj-5649	288	22	in	in	ADP
cusj-5649	288	23	order	order	NOUN
cusj-5649	288	24	to	to	PART
cusj-5649	288	25	determine	determine	VERB
cusj-5649	288	26	if	if	SCONJ
cusj-5649	288	27	increased	increase	VERB
cusj-5649	288	28	synthesis	synthesis	NOUN
cusj-5649	288	29	of	of	ADP
cusj-5649	288	30	any	any	DET
cusj-5649	288	31	other	other	ADJ
cusj-5649	288	32	protein	protein	NOUN
cusj-5649	288	33	would	would	AUX
cusj-5649	288	34	have	have	VERB
cusj-5649	288	35	the	the	DET
cusj-5649	288	36	same	same	ADJ
cusj-5649	288	37	e#ect	e#ect	NOUN
cusj-5649	288	38	on	on	ADP
cusj-5649	288	39	migration	migration	NOUN
cusj-5649	288	40	.	.	PUNCT
cusj-5649	289	1	we	we	PRON
cusj-5649	289	2	would	would	AUX
cusj-5649	289	3	also	also	ADV
cusj-5649	289	4	hope	hope	VERB
cusj-5649	289	5	to	to	PART
cusj-5649	289	6	obtain	obtain	VERB
cusj-5649	289	7	the	the	DET
cusj-5649	289	8	sirna	sirna	PROPN
cusj-5649	289	9	in	in	ADP
cusj-5649	289	10	order	order	NOUN
cusj-5649	289	11	to	to	PART
cusj-5649	289	12	knock	knock	VERB
cusj-5649	289	13	down	down	ADP
cusj-5649	289	14	pvr	pvr	NOUN
cusj-5649	289	15	,	,	PUNCT
cusj-5649	289	16	which	which	PRON
cusj-5649	289	17	was	be	AUX
cusj-5649	289	18	not	not	PART
cusj-5649	289	19	available	available	ADJ
cusj-5649	289	20	at	at	ADP
cusj-5649	289	21	the	the	DET
cusj-5649	289	22	time	time	NOUN
cusj-5649	289	23	.	.	PUNCT
cusj-5649	289	24	!	!	PUNCT
cusj-5649	290	1	e	e	NOUN
cusj-5649	290	2	challenge	challenge	NOUN
cusj-5649	290	3	we	we	PRON
cusj-5649	290	4	faced	face	VERB
cusj-5649	290	5	during	during	ADP
cusj-5649	290	6	this	this	DET
cusj-5649	290	7	experiment	experiment	NOUN
cusj-5649	290	8	was	be	AUX
cusj-5649	290	9	the	the	DET
cusj-5649	290	10	fact	fact	NOUN
cusj-5649	290	11	that	that	SCONJ
cusj-5649	290	12	cd155	cd155	PROPN
cusj-5649	290	13	is	be	AUX
cusj-5649	290	14	thought	think	VERB
cusj-5649	290	15	to	to	PART
cusj-5649	290	16	be	be	AUX
cusj-5649	290	17	a	a	DET
cusj-5649	290	18	uniquely	uniquely	ADV
cusj-5649	290	19	human	human	ADJ
cusj-5649	290	20	protein	protein	NOUN
cusj-5649	290	21	,	,	PUNCT
cusj-5649	290	22	because	because	SCONJ
cusj-5649	290	23	poliovirus	polioviru	NOUN
cusj-5649	290	24	only	only	ADV
cusj-5649	290	25	naturally	naturally	ADV
cusj-5649	290	26	infects	infect	VERB
cusj-5649	290	27	humans	human	NOUN
cusj-5649	290	28	.	.	PUNCT
cusj-5649	291	1	while	while	SCONJ
cusj-5649	291	2	mice	mouse	NOUN
cusj-5649	291	3	have	have	AUX
cusj-5649	291	4	been	be	AUX
cusj-5649	291	5	genetically	genetically	ADV
cusj-5649	291	6	engineered	engineer	VERB
cusj-5649	291	7	to	to	PART
cusj-5649	291	8	produce	produce	VERB
cusj-5649	291	9	references	reference	NOUN
cusj-5649	291	10	pvr	pvr	NOUN
cusj-5649	291	11	,	,	PUNCT
cusj-5649	291	12	we	we	PRON
cusj-5649	291	13	had	have	VERB
cusj-5649	291	14	no	no	DET
cusj-5649	291	15	predictions	prediction	NOUN
cusj-5649	291	16	as	as	ADP
cusj-5649	291	17	to	to	ADP
cusj-5649	291	18	whether	whether	SCONJ
cusj-5649	291	19	the	the	DET
cusj-5649	291	20	c6	c6	PROPN
cusj-5649	291	21	rat	rat	NOUN
cusj-5649	291	22	glioma	glioma	NOUN
cusj-5649	291	23	cells	cell	NOUN
cusj-5649	291	24	would	would	AUX
cusj-5649	291	25	express	express	VERB
cusj-5649	291	26	cd155	cd155	NOUN
cusj-5649	291	27	at	at	ADV
cusj-5649	291	28	all	all	ADV
cusj-5649	291	29	.	.	PUNCT
cusj-5649	292	1	cd155	cd155	NOUN
cusj-5649	292	2	analysis	analysis	NOUN
cusj-5649	292	3	has	have	AUX
cusj-5649	292	4	never	never	ADV
cusj-5649	292	5	been	be	AUX
cusj-5649	292	6	carried	carry	VERB
cusj-5649	292	7	out	out	ADP
cusj-5649	292	8	before	before	ADV
cusj-5649	292	9	in	in	ADP
cusj-5649	292	10	c6	c6	PROPN
cusj-5649	292	11	gliomas	glioma	NOUN
cusj-5649	292	12	.	.	PUNCT
cusj-5649	293	1	furthermore	furthermore	ADV
cusj-5649	293	2	,	,	PUNCT
cusj-5649	293	3	the	the	DET
cusj-5649	293	4	primary	primary	ADJ
cusj-5649	293	5	rat	rat	NOUN
cusj-5649	293	6	monoclonal	monoclonal	NOUN
cusj-5649	293	7	antibody	antibody	NOUN
cusj-5649	293	8	we	we	PRON
cusj-5649	293	9	used	use	VERB
cusj-5649	293	10	for	for	ADP
cusj-5649	293	11	our	our	PRON
cusj-5649	293	12	western	western	ADJ
cusj-5649	293	13	blots	blot	NOUN
cusj-5649	293	14	was	be	AUX
cusj-5649	293	15	expected	expect	VERB
cusj-5649	293	16	to	to	PART
cusj-5649	293	17	react	react	VERB
cusj-5649	293	18	with	with	ADP
cusj-5649	293	19	necl5	necl5	PROPN
cusj-5649	293	20	,	,	PUNCT
cusj-5649	293	21	the	the	DET
cusj-5649	293	22	mouse	mouse	NOUN
cusj-5649	293	23	origin	origin	NOUN
cusj-5649	293	24	of	of	ADP
cusj-5649	293	25	the	the	DET
cusj-5649	293	26	protein	protein	NOUN
cusj-5649	293	27	—	—	PUNCT
cusj-5649	293	28	and	and	CCONJ
cusj-5649	293	29	not	not	PART
cusj-5649	293	30	with	with	ADP
cusj-5649	293	31	the	the	DET
cusj-5649	293	32	human	human	ADJ
cusj-5649	293	33	origin	origin	NOUN
cusj-5649	293	34	cd155	cd155	PROPN
cusj-5649	293	35	.	.	PUNCT
cusj-5649	294	1	we	we	PRON
cusj-5649	294	2	were	be	AUX
cusj-5649	294	3	essentially	essentially	ADV
cusj-5649	294	4	testing	test	VERB
cusj-5649	294	5	to	to	PART
cusj-5649	294	6	see	see	VERB
cusj-5649	294	7	whether	whether	SCONJ
cusj-5649	294	8	our	our	PRON
cusj-5649	294	9	rat	rat	NOUN
cusj-5649	294	10	gliomas	glioma	NOUN
cusj-5649	294	11	do	do	AUX
cusj-5649	294	12	naturally	naturally	ADV
cusj-5649	294	13	express	express	VERB
cusj-5649	294	14	the	the	DET
cusj-5649	294	15	human	human	ADJ
cusj-5649	294	16	protein	protein	NOUN
cusj-5649	294	17	,	,	PUNCT
cusj-5649	294	18	and	and	CCONJ
cusj-5649	294	19	if	if	SCONJ
cusj-5649	294	20	the	the	DET
cusj-5649	294	21	mouse	mouse	NOUN
cusj-5649	294	22	antibody	antibody	NOUN
cusj-5649	294	23	would	would	AUX
cusj-5649	294	24	recognize	recognize	VERB
cusj-5649	294	25	the	the	DET
cusj-5649	294	26	human	human	ADJ
cusj-5649	294	27	homolog	homolog	NOUN
cusj-5649	294	28	.	.	PUNCT
cusj-5649	295	1	since	since	SCONJ
cusj-5649	295	2	the	the	DET
cusj-5649	295	3	blots	blot	NOUN
cusj-5649	295	4	con"rm	con"rm	NOUN
cusj-5649	295	5	that	that	SCONJ
cusj-5649	295	6	cd155	cd155	PROPN
cusj-5649	295	7	is	be	AUX
cusj-5649	295	8	indeed	indeed	ADV
cusj-5649	295	9	present	present	ADJ
cusj-5649	295	10	in	in	ADP
cusj-5649	295	11	c6	c6	PROPN
cusj-5649	295	12	cells	cell	NOUN
cusj-5649	295	13	,	,	PUNCT
cusj-5649	295	14	in	in	ADP
cusj-5649	295	15	an	an	DET
cusj-5649	295	16	amount	amount	NOUN
cusj-5649	295	17	comparable	comparable	ADJ
cusj-5649	295	18	to	to	ADP
cusj-5649	295	19	that	that	DET
cusj-5649	295	20	present	present	NOUN
cusj-5649	295	21	in	in	ADP
cusj-5649	295	22	u87	u87	ADJ
cusj-5649	295	23	human	human	ADJ
cusj-5649	295	24	cells	cell	NOUN
cusj-5649	295	25	,	,	PUNCT
cusj-5649	295	26	we	we	PRON
cusj-5649	295	27	can	can	AUX
cusj-5649	295	28	con"rm	con"rm	VERB
cusj-5649	295	29	that	that	SCONJ
cusj-5649	295	30	the	the	DET
cusj-5649	295	31	mouse	mouse	NOUN
cusj-5649	295	32	and	and	CCONJ
cusj-5649	295	33	human	human	ADJ
cusj-5649	295	34	homologs	homolog	NOUN
cusj-5649	295	35	of	of	ADP
cusj-5649	295	36	the	the	DET
cusj-5649	295	37	protein	protein	NOUN
cusj-5649	295	38	are	be	AUX
cusj-5649	295	39	similar	similar	ADJ
cusj-5649	295	40	.	.	PUNCT
cusj-5649	296	1	indeed	indeed	ADV
cusj-5649	296	2	,	,	PUNCT
cusj-5649	296	3	cd155	cd155	PROPN
cusj-5649	296	4	and	and	CCONJ
cusj-5649	296	5	necl-5	necl-5	NUM
cusj-5649	296	6	are	be	AUX
cusj-5649	296	7	referred	refer	VERB
cusj-5649	296	8	to	to	ADP
cusj-5649	296	9	in	in	ADP
cusj-5649	296	10	combination	combination	NOUN
cusj-5649	296	11	within	within	ADP
cusj-5649	296	12	scienti"c	scienti"c	NOUN
cusj-5649	296	13	dialogue	dialogue	NOUN
cusj-5649	296	14	and	and	CCONJ
cusj-5649	296	15	have	have	VERB
cusj-5649	296	16	virtually	virtually	ADV
cusj-5649	296	17	the	the	DET
cusj-5649	296	18	same	same	ADJ
cusj-5649	296	19	structure	structure	NOUN
cusj-5649	296	20	.	.	PUNCT
cusj-5649	297	1	yet	yet	ADV
cusj-5649	297	2	if	if	SCONJ
cusj-5649	297	3	the	the	DET
cusj-5649	297	4	antibody	antibody	NOUN
cusj-5649	297	5	treats	treat	VERB
cusj-5649	297	6	cd155	cd155	PROPN
cusj-5649	297	7	and	and	CCONJ
cusj-5649	297	8	necl-5	necl-5	NUM
cusj-5649	297	9	as	as	ADP
cusj-5649	297	10	the	the	DET
cusj-5649	297	11	same	same	ADJ
cusj-5649	297	12	protein	protein	NOUN
cusj-5649	297	13	,	,	PUNCT
cusj-5649	297	14	why	why	SCONJ
cusj-5649	297	15	is	be	AUX
cusj-5649	297	16	the	the	DET
cusj-5649	297	17	poliovirus	poliovirus	NOUN
cusj-5649	297	18	itself	itself	PRON
cusj-5649	297	19	speci"c	speci"c	NOUN
cusj-5649	297	20	to	to	ADP
cusj-5649	297	21	humans	human	NOUN
cusj-5649	297	22	?	?	PUNCT
cusj-5649	298	1	not	not	PART
cusj-5649	298	2	only	only	ADV
cusj-5649	298	3	do	do	AUX
cusj-5649	298	4	our	our	PRON
cusj-5649	298	5	"	"	PUNCT
cusj-5649	298	6	ndings	nding	NOUN
cusj-5649	298	7	shed	shed	VERB
cusj-5649	298	8	light	light	NOUN
cusj-5649	298	9	on	on	ADP
cusj-5649	298	10	the	the	DET
cusj-5649	298	11	strict	strict	ADJ
cusj-5649	298	12	nature	nature	NOUN
cusj-5649	298	13	of	of	ADP
cusj-5649	298	14	speci"city	speci"city	NOUN
cusj-5649	298	15	characteristic	characteristic	ADJ
cusj-5649	298	16	to	to	ADP
cusj-5649	298	17	viruses	virus	NOUN
cusj-5649	298	18	,	,	PUNCT
cusj-5649	298	19	but	but	CCONJ
cusj-5649	298	20	these	these	DET
cusj-5649	298	21	results	result	NOUN
cusj-5649	298	22	suggest	suggest	VERB
cusj-5649	298	23	that	that	SCONJ
cusj-5649	298	24	cd155	cd155	PROPN
cusj-5649	298	25	has	have	VERB
cusj-5649	298	26	more	more	ADJ
cusj-5649	298	27	than	than	ADP
cusj-5649	298	28	one	one	NUM
cusj-5649	298	29	function	function	NOUN
cusj-5649	298	30	besides	besides	SCONJ
cusj-5649	298	31	being	be	AUX
cusj-5649	298	32	the	the	DET
cusj-5649	298	33	human	human	ADJ
cusj-5649	298	34	receptor	receptor	NOUN
cusj-5649	298	35	for	for	ADP
cusj-5649	298	36	poliovirus	poliovirus	NOUN
cusj-5649	298	37	,	,	PUNCT
cusj-5649	298	38	and	and	CCONJ
cusj-5649	298	39	in	in	ADP
cusj-5649	298	40	concurrence	concurrence	NOUN
cusj-5649	298	41	with	with	ADP
cusj-5649	298	42	our	our	PRON
cusj-5649	298	43	assay	assay	NOUN
cusj-5649	298	44	counts	count	NOUN
cusj-5649	298	45	,	,	PUNCT
cusj-5649	298	46	does	do	AUX
cusj-5649	298	47	e#ect	e#ect	VERB
cusj-5649	298	48	migration	migration	NOUN
cusj-5649	298	49	on	on	ADP
cusj-5649	298	50	some	some	DET
cusj-5649	298	51	level	level	NOUN
cusj-5649	298	52	.	.	PUNCT
cusj-5649	299	1	although	although	SCONJ
cusj-5649	299	2	some	some	PRON
cusj-5649	299	3	of	of	ADP
cusj-5649	299	4	our	our	PRON
cusj-5649	299	5	counts	count	NOUN
cusj-5649	299	6	were	be	AUX
cusj-5649	299	7	not	not	PART
cusj-5649	299	8	statistically	statistically	ADV
cusj-5649	299	9	signi"cant	signi"cant	ADJ
cusj-5649	299	10	,	,	PUNCT
cusj-5649	299	11	what	what	PRON
cusj-5649	299	12	we	we	PRON
cusj-5649	299	13	do	do	AUX
cusj-5649	299	14	see	see	VERB
cusj-5649	299	15	is	be	AUX
cusj-5649	299	16	that	that	SCONJ
cusj-5649	299	17	the	the	DET
cusj-5649	299	18	second	second	ADJ
cusj-5649	299	19	assay	assay	NOUN
cusj-5649	299	20	with	with	ADP
cusj-5649	299	21	a	a	DET
cusj-5649	299	22	higher	high	ADJ
cusj-5649	299	23	concentration	concentration	NOUN
cusj-5649	299	24	of	of	ADP
cusj-5649	299	25	dna	dna	PROPN
cusj-5649	299	26	had	have	VERB
cusj-5649	299	27	an	an	DET
cusj-5649	299	28	overall	overall	ADJ
cusj-5649	299	29	much	much	ADV
cusj-5649	299	30	larger	large	ADJ
cusj-5649	299	31	percentage	percentage	NOUN
cusj-5649	299	32	di#erence	di#erence	NOUN
cusj-5649	299	33	than	than	ADP
cusj-5649	299	34	the	the	DET
cusj-5649	299	35	control	control	NOUN
cusj-5649	299	36	.	.	PUNCT
cusj-5649	300	1	if	if	SCONJ
cusj-5649	300	2	we	we	PRON
cusj-5649	300	3	know	know	VERB
cusj-5649	300	4	that	that	SCONJ
cusj-5649	300	5	the	the	DET
cusj-5649	300	6	c6	c6	PROPN
cusj-5649	300	7	cells	cell	NOUN
cusj-5649	300	8	contain	contain	VERB
cusj-5649	300	9	the	the	DET
cusj-5649	300	10	human	human	ADJ
cusj-5649	300	11	protein	protein	NOUN
cusj-5649	300	12	and	and	CCONJ
cusj-5649	300	13	their	their	PRON
cusj-5649	300	14	migration	migration	NOUN
cusj-5649	300	15	is	be	AUX
cusj-5649	300	16	in$uenced	in$uence	VERB
cusj-5649	300	17	by	by	ADP
cusj-5649	300	18	it	it	PRON
cusj-5649	300	19	,	,	PUNCT
cusj-5649	300	20	we	we	PRON
cusj-5649	300	21	can	can	AUX
cusj-5649	300	22	now	now	ADV
cusj-5649	300	23	potentially	potentially	ADV
cusj-5649	300	24	use	use	VERB
cusj-5649	300	25	rats	rat	NOUN
cusj-5649	300	26	as	as	ADP
cusj-5649	300	27	a	a	DET
cusj-5649	300	28	model	model	NOUN
cusj-5649	300	29	for	for	ADP
cusj-5649	300	30	cd155	cd155	PROPN
cusj-5649	300	31	/	/	SYM
cusj-5649	300	32	pvr	pvr	NOUN
cusj-5649	300	33	oncolytic	oncolytic	ADJ
cusj-5649	300	34	treatment	treatment	NOUN
cusj-5649	300	35	in	in	ADP
cusj-5649	300	36	humans	human	NOUN
cusj-5649	300	37	.	.	PUNCT
cusj-5649	301	1	a	a	DET
cusj-5649	301	2	study	study	NOUN
cusj-5649	301	3	done	do	VERB
cusj-5649	301	4	by	by	ADP
cusj-5649	301	5	the	the	DET
cusj-5649	301	6	department	department	NOUN
cusj-5649	301	7	of	of	ADP
cusj-5649	301	8	molecular	molecular	ADJ
cusj-5649	301	9	genetics	genetic	NOUN
cusj-5649	301	10	and	and	CCONJ
cusj-5649	301	11	microbiology	microbiology	NOUN
cusj-5649	301	12	at	at	ADP
cusj-5649	301	13	the	the	DET
cusj-5649	301	14	state	state	NOUN
cusj-5649	301	15	university	university	PROPN
cusj-5649	301	16	of	of	ADP
cusj-5649	301	17	new	new	PROPN
cusj-5649	301	18	york	york	PROPN
cusj-5649	301	19	(	(	PUNCT
cusj-5649	301	20	stony	stony	PROPN
cusj-5649	301	21	brook	brook	PROPN
cusj-5649	301	22	,	,	PUNCT
cusj-5649	301	23	ny	ny	PROPN
cusj-5649	301	24	)	)	PUNCT
cusj-5649	301	25	demonstrated	demonstrate	VERB
cusj-5649	301	26	for	for	ADP
cusj-5649	301	27	the	the	DET
cusj-5649	301	28	"	"	PUNCT
cusj-5649	301	29	rst	rst	ADJ
cusj-5649	301	30	time	time	NOUN
cusj-5649	301	31	that	that	PRON
cusj-5649	301	32	highly	highly	ADV
cusj-5649	301	33	attenuated	attenuate	VERB
cusj-5649	301	34	poliovirus	poliovirus	NOUN
cusj-5649	301	35	recombinants	recombinant	NOUN
cusj-5649	301	36	can	can	AUX
cusj-5649	301	37	infect	infect	VERB
cusj-5649	301	38	and	and	CCONJ
cusj-5649	301	39	propagate	propagate	VERB
cusj-5649	301	40	in	in	ADP
cusj-5649	301	41	cell	cell	NOUN
cusj-5649	301	42	lines	line	NOUN
cusj-5649	301	43	derived	derive	VERB
cusj-5649	301	44	from	from	ADP
cusj-5649	301	45	malignant	malignant	ADJ
cusj-5649	301	46	gliomas	glioma	NOUN
cusj-5649	301	47	and	and	CCONJ
cusj-5649	301	48	,	,	PUNCT
cusj-5649	301	49	most	most	ADV
cusj-5649	301	50	interestingly	interestingly	ADV
cusj-5649	301	51	,	,	PUNCT
cusj-5649	301	52	halted	halt	VERB
cusj-5649	301	53	tumor	tumor	NOUN
cusj-5649	301	54	progression	progression	NOUN
cusj-5649	301	55	and	and	CCONJ
cusj-5649	301	56	eliminated	eliminate	VERB
cusj-5649	301	57	tumors	tumor	NOUN
cusj-5649	301	58	in	in	ADP
cusj-5649	301	59	athymic	athymic	ADJ
cusj-5649	301	60	mice	mouse	NOUN
cusj-5649	301	61	.	.	PUNCT
cusj-5649	301	62	!	!	PUNCT
cusj-5649	302	1	ey	ey	PROPN
cusj-5649	302	2	proposed	propose	VERB
cusj-5649	302	3	that	that	SCONJ
cusj-5649	302	4	susceptibility	susceptibility	NOUN
cusj-5649	302	5	of	of	ADP
cusj-5649	302	6	these	these	DET
cusj-5649	302	7	malignant	malignant	ADJ
cusj-5649	302	8	cells	cell	NOUN
cusj-5649	302	9	to	to	ADP
cusj-5649	302	10	poliovirus	poliovirus	NOUN
cusj-5649	302	11	may	may	AUX
cusj-5649	302	12	be	be	AUX
cusj-5649	302	13	mediated	mediate	VERB
cusj-5649	302	14	by	by	ADP
cusj-5649	302	15	expression	expression	NOUN
cusj-5649	302	16	of	of	ADP
cusj-5649	302	17	the	the	DET
cusj-5649	302	18	cd155	cd155	NOUN
cusj-5649	302	19	gene	gene	NOUN
cusj-5649	302	20	in	in	ADP
cusj-5649	302	21	glial	glial	ADJ
cusj-5649	302	22	neoplasms	neoplasm	NOUN
cusj-5649	302	23	(	(	PUNCT
cusj-5649	302	24	gromeier	gromeier	NOUN
cusj-5649	302	25	,	,	PUNCT
cusj-5649	302	26	2000	2000	NUM
cusj-5649	302	27	)	)	PUNCT
cusj-5649	302	28	.	.	PUNCT
cusj-5649	303	1	as	as	ADP
cusj-5649	303	2	our	our	PRON
cusj-5649	303	3	understanding	understanding	NOUN
cusj-5649	303	4	of	of	ADP
cusj-5649	303	5	the	the	DET
cusj-5649	303	6	biology	biology	NOUN
cusj-5649	303	7	of	of	ADP
cusj-5649	303	8	brain	brain	NOUN
cusj-5649	303	9	cancer	cancer	NOUN
cusj-5649	303	10	progresses	progress	NOUN
cusj-5649	303	11	,	,	PUNCT
cusj-5649	303	12	new	new	ADJ
cusj-5649	303	13	knowledge	knowledge	NOUN
cusj-5649	303	14	about	about	ADP
cusj-5649	303	15	tumorigenesis	tumorigenesis	NOUN
cusj-5649	303	16	and	and	CCONJ
cusj-5649	303	17	tumor	tumor	NOUN
cusj-5649	303	18	biology	biology	NOUN
cusj-5649	303	19	can	can	AUX
cusj-5649	303	20	be	be	AUX
cusj-5649	303	21	used	use	VERB
cusj-5649	303	22	to	to	PART
cusj-5649	303	23	diagnose	diagnose	VERB
cusj-5649	303	24	,	,	PUNCT
cusj-5649	303	25	treat	treat	NOUN
cusj-5649	303	26	,	,	PUNCT
cusj-5649	303	27	and	and	CCONJ
cusj-5649	303	28	prevent	prevent	VERB
cusj-5649	303	29	this	this	DET
cusj-5649	303	30	type	type	NOUN
cusj-5649	303	31	of	of	ADP
cusj-5649	303	32	cancer	cancer	NOUN
cusj-5649	303	33	.	.	PUNCT
cusj-5649	304	1	our	our	PRON
cusj-5649	304	2	experiment	experiment	NOUN
cusj-5649	304	3	may	may	AUX
cusj-5649	304	4	help	help	VERB
cusj-5649	304	5	to	to	PART
cusj-5649	304	6	support	support	VERB
cusj-5649	304	7	the	the	DET
cusj-5649	304	8	concept	concept	NOUN
cusj-5649	304	9	that	that	PRON
cusj-5649	304	10	oncolytic	oncolytic	ADJ
cusj-5649	304	11	poliovirus	poliovirus	NOUN
cusj-5649	304	12	recombinants	recombinant	NOUN
cusj-5649	304	13	may	may	AUX
cusj-5649	304	14	be	be	AUX
cusj-5649	304	15	the	the	DET
cusj-5649	304	16	next	next	ADJ
cusj-5649	304	17	possible	possible	ADJ
cusj-5649	304	18	treatment	treatment	NOUN
cusj-5649	304	19	for	for	ADP
cusj-5649	304	20	malignant	malignant	ADJ
cusj-5649	304	21	glioma	glioma	NOUN
cusj-5649	304	22	.	.	PUNCT
cusj-5649	305	1	beadle	beadle	PROPN
cusj-5649	305	2	c	c	PROPN
cusj-5649	305	3	,	,	PUNCT
cusj-5649	305	4	assanah	assanah	PROPN
cusj-5649	305	5	mc	mc	PROPN
cusj-5649	305	6	,	,	PUNCT
cusj-5649	305	7	monzo	monzo	VERB
cusj-5649	305	8	p	p	NOUN
cusj-5649	305	9	,	,	PUNCT
cusj-5649	305	10	vallee	vallee	PROPN
cusj-5649	305	11	r	r	PROPN
cusj-5649	305	12	,	,	PUNCT
cusj-5649	305	13	rosenfeld	rosenfeld	PROPN
cusj-5649	305	14	ss	ss	PROPN
cusj-5649	305	15	,	,	PUNCT
cusj-5649	305	16	canoll	canoll	PROPN
cusj-5649	305	17	p.	p.	NOUN
cusj-5649	305	18	“	"	PUNCT
cusj-5649	305	19	!	!	PUNCT
cusj-5649	306	1	e	e	NOUN
cusj-5649	306	2	role	role	NOUN
cusj-5649	306	3	of	of	ADP
cusj-5649	306	4	myosin	myosin	PROPN
cusj-5649	306	5	ii	ii	PROPN
cusj-5649	306	6	in	in	ADP
cusj-5649	306	7	glioma	glioma	ADJ
cusj-5649	306	8	invasion	invasion	NOUN
cusj-5649	306	9	of	of	ADP
cusj-5649	306	10	the	the	DET
cusj-5649	306	11	brain	brain	NOUN
cusj-5649	306	12	.	.	PUNCT
cusj-5649	306	13	”	"	PUNCT
cusj-5649	307	1	mbc	mbc	PROPN
cusj-5649	307	2	:	:	PUNCT
cusj-5649	307	3	vol	vol	NOUN
cusj-5649	307	4	.	.	PROPN
cusj-5649	307	5	19	19	NUM
cusj-5649	307	6	,	,	PUNCT
cusj-5649	307	7	issue	issue	NOUN
cusj-5649	307	8	8	8	NUM
cusj-5649	307	9	,	,	PUNCT
cusj-5649	307	10	3357	3357	NUM
cusj-5649	307	11	-	-	SYM
cusj-5649	307	12	3368	3368	NUM
cusj-5649	307	13	.	.	PUNCT
cusj-5649	308	1	august	august	PROPN
cusj-5649	308	2	2008	2008	NUM
cusj-5649	308	3	.	.	PUNCT
cusj-5649	309	1	burgoyne	burgoyne	PROPN
cusj-5649	309	2	am	be	AUX
cusj-5649	309	3	,	,	PUNCT
cusj-5649	309	4	phillips	phillips	PROPN
cusj-5649	309	5	-	-	PUNCT
cusj-5649	309	6	mason	mason	PROPN
cusj-5649	309	7	pj	pj	PROPN
cusj-5649	309	8	,	,	PUNCT
cusj-5649	309	9	brady	brady	PROPN
cusj-5649	309	10	-	-	PUNCT
cusj-5649	309	11	kalnay	kalnay	PROPN
cusj-5649	309	12	sm	sm	PROPN
cusj-5649	309	13	,	,	PUNCT
cusj-5649	309	14	et	et	PROPN
cusj-5649	309	15	al	al	PROPN
cusj-5649	309	16	.	.	PUNCT
cusj-5649	310	1	“	"	PUNCT
cusj-5649	310	2	proteolytic	proteolytic	ADJ
cusj-5649	310	3	cleavage	cleavage	NOUN
cusj-5649	310	4	of	of	ADP
cusj-5649	310	5	protein	protein	NOUN
cusj-5649	310	6	tyrosine	tyrosine	NOUN
cusj-5649	310	7	phosphatase	phosphatase	NOUN
cusj-5649	310	8	mu	mu	PROPN
cusj-5649	310	9	regulates	regulate	VERB
cusj-5649	310	10	glioblastoma	glioblastoma	NOUN
cusj-5649	310	11	cell	cell	NOUN
cusj-5649	310	12	migration	migration	NOUN
cusj-5649	310	13	.	.	PUNCT
cusj-5649	310	14	”	"	PUNCT
cusj-5649	311	1	cancer	cancer	NOUN
cusj-5649	311	2	research	research	NOUN
cusj-5649	311	3	:	:	PUNCT
cusj-5649	311	4	6960	6960	NUM
cusj-5649	311	5	-	-	SYM
cusj-5649	311	6	6968	6968	NUM
cusj-5649	311	7	.	.	PUNCT
cusj-5649	312	1	august	august	PROPN
cusj-5649	312	2	18	18	NUM
cusj-5649	312	3	,	,	PUNCT
cusj-5649	312	4	2009	2009	NUM
cusj-5649	312	5	.	.	PUNCT
cusj-5649	313	1	giese	giese	ADJ
cusj-5649	313	2	a	a	X
cusj-5649	313	3	,	,	PUNCT
cusj-5649	313	4	et	et	PROPN
cusj-5649	313	5	al	al	PROPN
cusj-5649	313	6	.	.	PUNCT
cusj-5649	314	1	“	"	PUNCT
cusj-5649	314	2	cost	cost	NOUN
cusj-5649	314	3	of	of	ADP
cusj-5649	314	4	migration	migration	NOUN
cusj-5649	314	5	:	:	PUNCT
cusj-5649	314	6	invasion	invasion	NOUN
cusj-5649	314	7	of	of	ADP
cusj-5649	314	8	malignant	malignant	ADJ
cusj-5649	314	9	gliomas	glioma	NOUN
cusj-5649	314	10	and	and	CCONJ
cusj-5649	314	11	implications	implication	NOUN
cusj-5649	314	12	for	for	ADP
cusj-5649	314	13	treatment	treatment	NOUN
cusj-5649	314	14	.	.	PUNCT
cusj-5649	314	15	”	"	PUNCT
cusj-5649	315	1	american	american	ADJ
cusj-5649	315	2	society	society	NOUN
cusj-5649	315	3	of	of	ADP
cusj-5649	315	4	clinical	clinical	ADJ
cusj-5649	315	5	oncology	oncology	NOUN
cusj-5649	315	6	:	:	PUNCT
cusj-5649	315	7	1624	1624	NUM
cusj-5649	315	8	-	-	SYM
cusj-5649	315	9	1635	1635	NUM
cusj-5649	315	10	.	.	PUNCT
cusj-5649	316	1	2003	2003	NUM
cusj-5649	316	2	.	.	PUNCT
cusj-5649	317	1	gillespie	gillespie	PROPN
cusj-5649	317	2	gy	gy	PROPN
cusj-5649	317	3	,	,	PUNCT
cusj-5649	317	4	soroceanu	soroceanu	NOUN
cusj-5649	317	5	l	l	NOUN
cusj-5649	317	6	,	,	PUNCT
cusj-5649	317	7	manning	man	VERB
cusj-5649	317	8	tj	tj	PROPN
cusj-5649	317	9	,	,	PUNCT
cusj-5649	317	10	gladson	gladson	PROPN
cusj-5649	317	11	cl	cl	PROPN
cusj-5649	317	12	,	,	PUNCT
cusj-5649	317	13	rosenfeld	rosenfeld	PROPN
cusj-5649	317	14	ss	ss	PROPN
cusj-5649	317	15	.	.	PUNCT
cusj-5649	318	1	“	"	PUNCT
cusj-5649	318	2	glioma	glioma	NOUN
cusj-5649	318	3	migration	migration	NOUN
cusj-5649	318	4	can	can	AUX
cusj-5649	318	5	be	be	AUX
cusj-5649	318	6	blocked	block	VERB
cusj-5649	318	7	by	by	ADP
cusj-5649	318	8	nontoxic	nontoxic	ADJ
cusj-5649	318	9	inhibitors	inhibitor	NOUN
cusj-5649	318	10	of	of	ADP
cusj-5649	318	11	myosin	myosin	PROPN
cusj-5649	318	12	ii	ii	PROPN
cusj-5649	318	13	.	.	PUNCT
cusj-5649	318	14	”	"	PUNCT
cusj-5649	319	1	cancer	cancer	NOUN
cusj-5649	319	2	research	research	NOUN
cusj-5649	319	3	:	:	PUNCT
cusj-5649	319	4	2076	2076	NUM
cusj-5649	319	5	-	-	SYM
cusj-5649	319	6	2082	2082	NUM
cusj-5649	319	7	.	.	PUNCT
cusj-5649	320	1	may	may	AUX
cusj-5649	320	2	1999	1999	NUM
cusj-5649	320	3	.	.	PUNCT
cusj-5649	321	1	gromeier	gromei	ADJ
cusj-5649	321	2	m	m	PROPN
cusj-5649	321	3	,	,	PUNCT
cusj-5649	321	4	lachmann	lachmann	PROPN
cusj-5649	321	5	s	s	PROPN
cusj-5649	321	6	,	,	PUNCT
cusj-5649	321	7	rosenfeld	rosenfeld	PROPN
cusj-5649	321	8	mr	mr	PROPN
cusj-5649	321	9	,	,	PUNCT
cusj-5649	321	10	et	et	PROPN
cusj-5649	321	11	al	al	PROPN
cusj-5649	321	12	.	.	PUNCT
cusj-5649	322	1	“	"	PUNCT
cusj-5649	322	2	intergeneric	intergeneric	ADJ
cusj-5649	322	3	poliovirus	poliovirus	NOUN
cusj-5649	322	4	recombinants	recombinant	NOUN
cusj-5649	322	5	for	for	ADP
cusj-5649	322	6	the	the	DET
cusj-5649	322	7	treatment	treatment	NOUN
cusj-5649	322	8	of	of	ADP
cusj-5649	322	9	malignant	malignant	ADJ
cusj-5649	322	10	glioma	glioma	NOUN
cusj-5649	322	11	.	.	PUNCT
cusj-5649	322	12	”	"	PUNCT
cusj-5649	323	1	proc	proc	PROPN
cusj-5649	323	2	natl	natl	PROPN
cusj-5649	323	3	acad	acad	PROPN
cusj-5649	323	4	sci	sci	PROPN
cusj-5649	323	5	usa	usa	PROPN
cusj-5649	323	6	:	:	PUNCT
cusj-5649	323	7	6803–6808	6803–6808	NUM
cusj-5649	323	8	.	.	PUNCT
cusj-5649	323	9	june	june	PROPN
cusj-5649	323	10	6	6	NUM
cusj-5649	323	11	,	,	PUNCT
cusj-5649	323	12	2000	2000	NUM
cusj-5649	323	13	.	.	PUNCT
cusj-5649	324	1	madsen	madsen	PROPN
cusj-5649	324	2	sj	sj	PROPN
cusj-5649	324	3	,	,	PUNCT
cusj-5649	324	4	sun	sun	PROPN
cusj-5649	324	5	ch	ch	PROPN
cusj-5649	324	6	,	,	PUNCT
cusj-5649	324	7	tromberg	tromberg	PROPN
cusj-5649	324	8	bj	bj	PROPN
cusj-5649	324	9	,	,	PUNCT
cusj-5649	324	10	cristini	cristini	PROPN
cusj-5649	324	11	v	v	NOUN
cusj-5649	324	12	,	,	PUNCT
cusj-5649	324	13	de	de	X
cusj-5649	324	14	magalha	magalha	NOUN
cusj-5649	324	15	n	n	CCONJ
cusj-5649	324	16	,	,	PUNCT
cusj-5649	324	17	hirschberg	hirschberg	PROPN
cusj-5649	324	18	h.	h.	PROPN
cusj-5649	325	1	“	"	PUNCT
cusj-5649	325	2	multicell	multicell	PROPN
cusj-5649	325	3	tumor	tumor	NOUN
cusj-5649	325	4	spheroids	spheroid	NOUN
cusj-5649	325	5	in	in	ADP
cusj-5649	325	6	photodynamic	photodynamic	ADJ
cusj-5649	325	7	!	!	PUNCT
cusj-5649	325	8	erapy	erapy	NOUN
cusj-5649	325	9	.	.	PUNCT
cusj-5649	325	10	”	"	PUNCT
cusj-5649	326	1	lasers	laser	NOUN
cusj-5649	326	2	in	in	ADP
cusj-5649	326	3	surgery	surgery	NOUN
cusj-5649	326	4	and	and	CCONJ
cusj-5649	326	5	medicine	medicine	NOUN
cusj-5649	326	6	:	:	PUNCT
cusj-5649	327	1	555–564	555–564	NUM
cusj-5649	327	2	.	.	PUNCT
cusj-5649	328	1	2006	2006	NUM
cusj-5649	328	2	.	.	PUNCT
cusj-5649	329	1	merrill	merrill	PROPN
cusj-5649	329	2	mk	mk	PROPN
cusj-5649	329	3	,	,	PUNCT
cusj-5649	329	4	bernhardt	bernhardt	PROPN
cusj-5649	329	5	g	g	PROPN
cusj-5649	329	6	,	,	PUNCT
cusj-5649	329	7	sampson	sampson	PROPN
cusj-5649	329	8	jh	jh	PROPN
cusj-5649	329	9	,	,	PUNCT
cusj-5649	329	10	wikstrand	wikstrand	PROPN
cusj-5649	329	11	cj	cj	PROPN
cusj-5649	329	12	,	,	PUNCT
cusj-5649	329	13	bigner	bigner	NOUN
cusj-5649	329	14	dd	dd	NOUN
cusj-5649	329	15	,	,	PUNCT
cusj-5649	329	16	gromeier	gromeier	ADJ
cusj-5649	329	17	m.	m.	NOUN
cusj-5649	329	18	“	"	PUNCT
cusj-5649	329	19	poliovirus	poliovirus	NOUN
cusj-5649	329	20	receptor	receptor	NOUN
cusj-5649	329	21	cd155	cd155	NOUN
cusj-5649	329	22	-	-	PUNCT
cusj-5649	329	23	targeted	target	VERB
cusj-5649	329	24	oncolysis	oncolysis	NOUN
cusj-5649	329	25	of	of	ADP
cusj-5649	329	26	glioma	glioma	NOUN
cusj-5649	329	27	.	.	PUNCT
cusj-5649	329	28	”	"	PUNCT
cusj-5649	330	1	neuro	neuro	ADJ
cusj-5649	330	2	-	-	PUNCT
cusj-5649	330	3	oncology	oncology	NOUN
cusj-5649	330	4	:	:	PUNCT
cusj-5649	330	5	208	208	NUM
cusj-5649	330	6	-	-	SYM
cusj-5649	330	7	217	217	NUM
cusj-5649	330	8	.	.	PUNCT
cusj-5649	331	1	2004	2004	NUM
cusj-5649	331	2	.	.	PUNCT
cusj-5649	332	1	pliaka	pliaka	PROPN
cusj-5649	332	2	v	v	PROPN
cusj-5649	332	3	,	,	PUNCT
cusj-5649	332	4	dedepsidis	dedepsidis	PROPN
cusj-5649	332	5	e	e	NOUN
cusj-5649	332	6	,	,	PUNCT
cusj-5649	332	7	kyriakopoulou	kyriakopoulou	PROPN
cusj-5649	332	8	z	z	PROPN
cusj-5649	332	9	,	,	PUNCT
cusj-5649	332	10	papadopoulou	papadopoulou	PROPN
cusj-5649	332	11	i	i	PROPN
cusj-5649	332	12	,	,	PUNCT
cusj-5649	332	13	levidiotou	levidiotou	PROPN
cusj-5649	332	14	s	s	PROPN
cusj-5649	332	15	,	,	PUNCT
cusj-5649	332	16	markoulatos	markoulato	VERB
cusj-5649	332	17	p.	p.	NOUN
cusj-5649	332	18	“	"	PUNCT
cusj-5649	332	19	use	use	NOUN
cusj-5649	332	20	of	of	ADP
cusj-5649	332	21	mutational	mutational	ADJ
cusj-5649	332	22	pattern	pattern	NOUN
cusj-5649	332	23	in	in	ADP
cusj-5649	332	24	5’-ncr	5’-ncr	NUM
cusj-5649	332	25	and	and	CCONJ
cusj-5649	332	26	vp1	vp1	NOUN
cusj-5649	332	27	regions	region	NOUN
cusj-5649	332	28	of	of	ADP
cusj-5649	332	29	polioviruses	poliovirus	NOUN
cusj-5649	332	30	for	for	ADP
cusj-5649	332	31	molecular	molecular	ADJ
cusj-5649	332	32	diagnosis	diagnosis	NOUN
cusj-5649	332	33	.	.	PUNCT
cusj-5649	332	34	”	"	PUNCT
cusj-5649	333	1	molecular	molecular	ADJ
cusj-5649	333	2	and	and	CCONJ
cusj-5649	333	3	cellular	cellular	ADJ
cusj-5649	333	4	probes	probe	NOUN
cusj-5649	333	5	:	:	PUNCT
cusj-5649	333	6	vol	vol	NOUN
cusj-5649	333	7	.	.	PROPN
cusj-5649	333	8	21	21	NUM
cusj-5649	333	9	,	,	PUNCT
cusj-5649	333	10	issue	issue	NOUN
cusj-5649	333	11	4	4	NUM
cusj-5649	333	12	,	,	PUNCT
cusj-5649	333	13	267	267	NUM
cusj-5649	333	14	-	-	SYM
cusj-5649	333	15	275	275	NUM
cusj-5649	333	16	.	.	PUNCT
cusj-5649	334	1	august	august	PROPN
cusj-5649	334	2	2007	2007	NUM
cusj-5649	334	3	.	.	PUNCT
cusj-5649	335	1	sloan	sloan	PROPN
cusj-5649	335	2	ke	ke	PROPN
cusj-5649	335	3	,	,	PUNCT
cusj-5649	335	4	stewart	stewart	PROPN
cusj-5649	335	5	jk	jk	PROPN
cusj-5649	335	6	,	,	PUNCT
cusj-5649	335	7	treloar	treloar	PROPN
cusj-5649	335	8	af	af	PROPN
cusj-5649	335	9	,	,	PUNCT
cusj-5649	335	10	matthews	matthews	PROPN
cusj-5649	335	11	rt	rt	PROPN
cusj-5649	335	12	,	,	PUNCT
cusj-5649	335	13	jay	jay	PROPN
cusj-5649	335	14	dg	dg	PROPN
cusj-5649	335	15	.	.	PUNCT
cusj-5649	336	1	“	"	PUNCT
cusj-5649	336	2	cd155	cd155	PROPN
cusj-5649	336	3	/	/	SYM
cusj-5649	336	4	pvr	pvr	NOUN
cusj-5649	336	5	enhances	enhance	VERB
cusj-5649	336	6	glioma	glioma	NOUN
cusj-5649	336	7	cell	cell	NOUN
cusj-5649	336	8	dispersal	dispersal	NOUN
cusj-5649	336	9	by	by	ADP
cusj-5649	336	10	regulating	regulate	VERB
cusj-5649	336	11	adhesion	adhesion	NOUN
cusj-5649	336	12	signaling	signal	VERB
cusj-5649	336	13	and	and	CCONJ
cusj-5649	336	14	focal	focal	ADJ
cusj-5649	336	15	adhesion	adhesion	NOUN
cusj-5649	336	16	dynamics	dynamic	NOUN
cusj-5649	336	17	.	.	PUNCT
cusj-5649	336	18	”	"	PUNCT
cusj-5649	337	1	cancer	cancer	NOUN
cusj-5649	337	2	research	research	NOUN
cusj-5649	337	3	:	:	PUNCT
cusj-5649	337	4	10930–10937	10930–10937	NUM
cusj-5649	337	5	.	.	PUNCT
cusj-5649	338	1	december	december	PROPN
cusj-5649	338	2	1	1	NUM
cusj-5649	338	3	,	,	PUNCT
cusj-5649	338	4	2005	2005	NUM
cusj-5649	338	5	.	.	PUNCT
cusj-5649	339	1	solecki	solecki	PROPN
cusj-5649	339	2	dj	dj	PROPN
cusj-5649	339	3	,	,	PUNCT
cusj-5649	339	4	gromeir	gromeir	PROPN
cusj-5649	339	5	m	m	NOUN
cusj-5649	339	6	,	,	PUNCT
cusj-5649	339	7	mueller	mueller	PROPN
cusj-5649	339	8	s	s	PROPN
cusj-5649	339	9	,	,	PUNCT
cusj-5649	339	10	bernhardt	bernhardt	PROPN
cusj-5649	339	11	g	g	PROPN
cusj-5649	339	12	,	,	PUNCT
cusj-5649	339	13	wimmer	wimmer	PROPN
cusj-5649	339	14	e.	e.	PROPN
cusj-5649	340	1	“	"	PUNCT
cusj-5649	340	2	expression	expression	NOUN
cusj-5649	340	3	of	of	ADP
cusj-5649	340	4	the	the	DET
cusj-5649	340	5	human	human	ADJ
cusj-5649	340	6	poliovirus	poliovirus	NOUN
cusj-5649	340	7	receptor	receptor	NOUN
cusj-5649	340	8	/	/	SYM
cusj-5649	340	9	cd155	cd155	NOUN
cusj-5649	340	10	gene	gene	NOUN
cusj-5649	340	11	is	be	AUX
cusj-5649	340	12	activated	activate	VERB
cusj-5649	340	13	by	by	ADP
cusj-5649	340	14	sonic	sonic	ADJ
cusj-5649	340	15	hedgehog	hedgehog	NOUN
cusj-5649	340	16	.	.	PUNCT
cusj-5649	340	17	”	"	PUNCT
cusj-5649	340	18	!	!	PUNCT
cusj-5649	341	1	e	e	PROPN
cusj-5649	341	2	journal	journal	NOUN
cusj-5649	341	3	of	of	ADP
cusj-5649	341	4	biological	biological	ADJ
cusj-5649	341	5	chemistry	chemistry	NOUN
cusj-5649	341	6	:	:	PUNCT
cusj-5649	341	7	277	277	NUM
cusj-5649	341	8	,	,	PUNCT
cusj-5649	341	9	25697	25697	NUM
cusj-5649	341	10	-	-	SYM
cusj-5649	341	11	25702	25702	NUM
cusj-5649	341	12	.	.	PUNCT
cusj-5649	342	1	april	april	PROPN
cusj-5649	342	2	30	30	NUM
cusj-5649	342	3	,	,	PUNCT
cusj-5649	342	4	2002	2002	NUM
cusj-5649	342	5	zhang	zhang	PROPN
cusj-5649	343	1	p	p	X
cusj-5649	343	2	,	,	PUNCT
cusj-5649	343	3	mueller	mueller	PROPN
cusj-5649	343	4	s.	s.	PROPN
cusj-5649	343	5	“	"	PUNCT
cusj-5649	343	6	crystal	crystal	NOUN
cusj-5649	343	7	structure	structure	NOUN
cusj-5649	343	8	of	of	ADP
cusj-5649	343	9	cd155	cd155	PROPN
cusj-5649	343	10	and	and	CCONJ
cusj-5649	343	11	electron	electron	NOUN
cusj-5649	343	12	microscopic	microscopic	ADJ
cusj-5649	343	13	studies	study	NOUN
cusj-5649	343	14	of	of	ADP
cusj-5649	343	15	its	its	PRON
cusj-5649	343	16	complexes	complex	NOUN
cusj-5649	343	17	with	with	ADP
cusj-5649	343	18	polioviruses	poliovirus	NOUN
cusj-5649	343	19	.	.	PUNCT
cusj-5649	343	20	”	"	PUNCT
cusj-5649	344	1	pnas	pna	NOUN
cusj-5649	344	2	:	:	PUNCT
cusj-5649	344	3	vol	vol	NOUN
cusj-5649	344	4	.	.	PROPN
cusj-5649	344	5	105	105	NUM
cusj-5649	344	6	,	,	PUNCT
cusj-5649	344	7	no	no	INTJ
cusj-5649	344	8	.	.	NOUN
cusj-5649	344	9	47	47	NUM
cusj-5649	344	10	,	,	PUNCT
cusj-5649	344	11	18284	18284	NUM
cusj-5649	344	12	-	-	SYM
cusj-5649	344	13	18289	18289	NUM
cusj-5649	344	14	.	.	PUNCT
cusj-5649	345	1	november	november	PROPN
cusj-5649	345	2	2008	2008	NUM
cusj-5649	345	3	.	.	PUNCT
cusj-5649	346	1	figure	figure	VERB
cusj-5649	346	2	5	5	NUM
cusj-5649	346	3	western	western	ADJ
cusj-5649	346	4	blot	blot	NOUN
cusj-5649	346	5	ac6	ac6	PROPN
cusj-5649	346	6	control	control	PROPN
cusj-5649	346	7	vs	vs	ADP
cusj-5649	346	8	c6	c6	PROPN
cusj-5649	346	9	transfection	transfection	NOUN
cusj-5649	346	10	with	with	ADP
cusj-5649	346	11	pvr	pvr	PROPN
cusj-5649	346	12	western	western	ADJ
cusj-5649	346	13	blot	blot	NOUN
cusj-5649	346	14	bc6	bc6	NOUN
cusj-5649	346	15	control	control	NOUN
cusj-5649	346	16	vs	vs	ADP
cusj-5649	346	17	u87	u87	ADJ
cusj-5649	346	18	controlfigure	controlfigure	NOUN
cusj-5649	346	19	6	6	NUM
cusj-5649	346	20	discussion	discussion	NOUN
