id	sid	tid	token	lemma	pos
cusj-7408	1	1	6	6	NUM
cusj-7408	1	2	microbiome	microbiome	ADJ
cusj-7408	1	3	composition	composition	NOUN
cusj-7408	1	4	and	and	CCONJ
cusj-7408	1	5	circadian	circadian	ADJ
cusj-7408	1	6	rhythm	rhythm	NOUN
cusj-7408	1	7	disruption	disruption	NOUN
cusj-7408	1	8	alters	alter	VERB
cusj-7408	1	9	epithelial	epithelial	ADJ
cusj-7408	1	10	barrier	barrier	NOUN
cusj-7408	1	11	integrity	integrity	NOUN
cusj-7408	1	12	elisha	elisha	PROPN
cusj-7408	1	13	pinker1	pinker1	PROPN
cusj-7408	1	14	,	,	PUNCT
cusj-7408	1	15	timur	timur	ADJ
cusj-7408	1	16	tuganbaev2	tuganbaev2	NOUN
cusj-7408	1	17	1columbia	1columbia	NUM
cusj-7408	1	18	university	university	NOUN
cusj-7408	1	19	,	,	PUNCT
cusj-7408	1	20	new	new	PROPN
cusj-7408	1	21	york	york	PROPN
cusj-7408	1	22	,	,	PUNCT
cusj-7408	1	23	ny	ny	PROPN
cusj-7408	1	24	,	,	PUNCT
cusj-7408	1	25	usa	usa	PROPN
cusj-7408	1	26	2lab	2lab	NUM
cusj-7408	1	27	of	of	ADP
cusj-7408	1	28	dr	dr	PROPN
cusj-7408	1	29	.	.	PROPN
cusj-7408	1	30	eran	eran	PROPN
cusj-7408	1	31	elinav	elinav	PROPN
cusj-7408	1	32	;	;	PUNCT
cusj-7408	1	33	department	department	NOUN
cusj-7408	1	34	of	of	ADP
cusj-7408	1	35	immunology	immunology	NOUN
cusj-7408	1	36	,	,	PUNCT
cusj-7408	1	37	weizmann	weizmann	PROPN
cusj-7408	1	38	institute	institute	PROPN
cusj-7408	1	39	of	of	ADP
cusj-7408	1	40	science	science	PROPN
cusj-7408	1	41	,	,	PUNCT
cusj-7408	1	42	israel	israel	PROPN
cusj-7408	1	43	abstract	abstract	NOUN
cusj-7408	1	44	:	:	PUNCT
cusj-7408	1	45	the	the	DET
cusj-7408	1	46	intestine	intestine	NOUN
cusj-7408	1	47	is	be	AUX
cusj-7408	1	48	home	home	NOUN
cusj-7408	1	49	to	to	ADP
cusj-7408	1	50	one	one	NUM
cusj-7408	1	51	of	of	ADP
cusj-7408	1	52	the	the	DET
cusj-7408	1	53	most	most	ADV
cusj-7408	1	54	complex	complex	ADJ
cusj-7408	1	55	ecological	ecological	ADJ
cusj-7408	1	56	communities	community	NOUN
cusj-7408	1	57	,	,	PUNCT
cusj-7408	1	58	termed	term	VERB
cusj-7408	1	59	the	the	DET
cusj-7408	1	60	human	human	ADJ
cusj-7408	1	61	gut	gut	NOUN
cusj-7408	1	62	microbiome	microbiome	NOUN
cusj-7408	1	63	.	.	PUNCT
cusj-7408	2	1	the	the	DET
cusj-7408	2	2	gut	gut	NOUN
cusj-7408	2	3	microbiome	microbiome	NOUN
cusj-7408	2	4	modulates	modulate	NOUN
cusj-7408	2	5	a	a	DET
cusj-7408	2	6	wide	wide	ADJ
cusj-7408	2	7	range	range	NOUN
cusj-7408	2	8	of	of	ADP
cusj-7408	2	9	human	human	ADJ
cusj-7408	2	10	diseases	disease	NOUN
cusj-7408	2	11	from	from	ADP
cusj-7408	2	12	diabetes	diabetes	NOUN
cusj-7408	2	13	to	to	ADP
cusj-7408	2	14	neurological	neurological	ADJ
cusj-7408	2	15	disorders	disorder	NOUN
cusj-7408	2	16	to	to	ADP
cusj-7408	2	17	cancer	cancer	NOUN
cusj-7408	2	18	.	.	PUNCT
cusj-7408	3	1	separating	separate	VERB
cusj-7408	3	2	the	the	DET
cusj-7408	3	3	host	host	NOUN
cusj-7408	3	4	and	and	CCONJ
cusj-7408	3	5	the	the	DET
cusj-7408	3	6	gut	gut	NOUN
cusj-7408	3	7	microbiome	microbiome	NOUN
cusj-7408	3	8	is	be	AUX
cusj-7408	3	9	the	the	DET
cusj-7408	3	10	epithelial	epithelial	ADJ
cusj-7408	3	11	barrier	barrier	NOUN
cusj-7408	3	12	.	.	PUNCT
cusj-7408	4	1	the	the	DET
cusj-7408	4	2	intestinal	intestinal	ADJ
cusj-7408	4	3	epithelium	epithelium	NOUN
cusj-7408	4	4	serves	serve	VERB
cusj-7408	4	5	as	as	ADP
cusj-7408	4	6	an	an	DET
cusj-7408	4	7	adaptive	adaptive	ADJ
cusj-7408	4	8	interaction	interaction	NOUN
cusj-7408	4	9	hub	hub	NOUN
cusj-7408	4	10	between	between	ADP
cusj-7408	4	11	the	the	DET
cusj-7408	4	12	host	host	NOUN
cusj-7408	4	13	and	and	CCONJ
cusj-7408	4	14	microbiome	microbiome	NOUN
cusj-7408	4	15	that	that	PRON
cusj-7408	4	16	plays	play	VERB
cusj-7408	4	17	an	an	DET
cusj-7408	4	18	important	important	ADJ
cusj-7408	4	19	role	role	NOUN
cusj-7408	4	20	in	in	ADP
cusj-7408	4	21	deciding	decide	VERB
cusj-7408	4	22	the	the	DET
cusj-7408	4	23	outcome	outcome	NOUN
cusj-7408	4	24	of	of	ADP
cusj-7408	4	25	host	host	NOUN
cusj-7408	4	26	-	-	PUNCT
cusj-7408	4	27	microbiome	microbiome	NOUN
cusj-7408	4	28	interactions	interaction	NOUN
cusj-7408	4	29	.	.	PUNCT
cusj-7408	5	1	regulation	regulation	NOUN
cusj-7408	5	2	of	of	ADP
cusj-7408	5	3	epithelial	epithelial	ADJ
cusj-7408	5	4	barrier	barrier	NOUN
cusj-7408	5	5	permeability	permeability	NOUN
cusj-7408	5	6	to	to	ADP
cusj-7408	5	7	ions	ion	NOUN
cusj-7408	5	8	,	,	PUNCT
cusj-7408	5	9	nutrients	nutrient	NOUN
cusj-7408	5	10	and	and	CCONJ
cusj-7408	5	11	microbiome	microbiome	ADJ
cusj-7408	5	12	metabolites	metabolite	NOUN
cusj-7408	5	13	is	be	AUX
cusj-7408	5	14	known	know	VERB
cusj-7408	5	15	to	to	PART
cusj-7408	5	16	be	be	AUX
cusj-7408	5	17	a	a	DET
cusj-7408	5	18	tightly	tightly	ADV
cusj-7408	5	19	controlled	control	VERB
cusj-7408	5	20	process	process	NOUN
cusj-7408	5	21	on	on	ADP
cusj-7408	5	22	the	the	DET
cusj-7408	5	23	host	host	NOUN
cusj-7408	5	24	side	side	NOUN
cusj-7408	5	25	.	.	PUNCT
cusj-7408	6	1	while	while	SCONJ
cusj-7408	6	2	previous	previous	ADJ
cusj-7408	6	3	studies	study	NOUN
cusj-7408	6	4	have	have	AUX
cusj-7408	6	5	identified	identify	VERB
cusj-7408	6	6	the	the	DET
cusj-7408	6	7	microbiome	microbiome	NOUN
cusj-7408	6	8	as	as	ADP
cusj-7408	6	9	a	a	DET
cusj-7408	6	10	factor	factor	NOUN
cusj-7408	6	11	for	for	ADP
cusj-7408	6	12	epithelial	epithelial	ADJ
cusj-7408	6	13	permeability	permeability	NOUN
cusj-7408	6	14	,	,	PUNCT
cusj-7408	6	15	the	the	DET
cusj-7408	6	16	exact	exact	ADJ
cusj-7408	6	17	mechanisms	mechanism	NOUN
cusj-7408	6	18	through	through	ADP
cusj-7408	6	19	which	which	PRON
cusj-7408	6	20	it	it	PRON
cusj-7408	6	21	mediates	mediate	VERB
cusj-7408	6	22	remains	remain	VERB
cusj-7408	6	23	less	less	ADV
cusj-7408	6	24	clear	clear	ADJ
cusj-7408	6	25	.	.	PUNCT
cusj-7408	7	1	here	here	ADV
cusj-7408	7	2	,	,	PUNCT
cusj-7408	7	3	we	we	PRON
cusj-7408	7	4	show	show	VERB
cusj-7408	7	5	that	that	SCONJ
cusj-7408	7	6	alterations	alteration	NOUN
cusj-7408	7	7	in	in	ADP
cusj-7408	7	8	microbiota	microbiota	NOUN
cusj-7408	7	9	composition	composition	NOUN
cusj-7408	7	10	by	by	ADP
cusj-7408	7	11	treatment	treatment	NOUN
cusj-7408	7	12	with	with	ADP
cusj-7408	7	13	antibiotics	antibiotic	NOUN
cusj-7408	7	14	selectively	selectively	ADV
cusj-7408	7	15	targeting	target	VERB
cusj-7408	7	16	specific	specific	ADJ
cusj-7408	7	17	members	member	NOUN
cusj-7408	7	18	of	of	ADP
cusj-7408	7	19	the	the	DET
cusj-7408	7	20	microbiome	microbiome	NOUN
cusj-7408	7	21	community	community	NOUN
cusj-7408	7	22	impacts	impact	VERB
cusj-7408	7	23	the	the	DET
cusj-7408	7	24	permeability	permeability	NOUN
cusj-7408	7	25	of	of	ADP
cusj-7408	7	26	the	the	DET
cusj-7408	7	27	intestine	intestine	NOUN
cusj-7408	7	28	.	.	PUNCT
cusj-7408	8	1	additionally	additionally	ADV
cusj-7408	8	2	,	,	PUNCT
cusj-7408	8	3	modulating	modulate	VERB
cusj-7408	8	4	the	the	DET
cusj-7408	8	5	microbiome	microbiome	NOUN
cusj-7408	8	6	through	through	ADP
cusj-7408	8	7	other	other	ADJ
cusj-7408	8	8	methods	method	NOUN
cusj-7408	8	9	such	such	ADJ
cusj-7408	8	10	as	as	ADP
cusj-7408	8	11	altering	alter	VERB
cusj-7408	8	12	diet	diet	NOUN
cusj-7408	8	13	composition	composition	NOUN
cusj-7408	8	14	shows	show	VERB
cusj-7408	8	15	changes	change	NOUN
cusj-7408	8	16	in	in	ADP
cusj-7408	8	17	permeability	permeability	NOUN
cusj-7408	8	18	of	of	ADP
cusj-7408	8	19	the	the	DET
cusj-7408	8	20	epithelial	epithelial	ADJ
cusj-7408	8	21	barrier	barrier	NOUN
cusj-7408	8	22	.	.	PUNCT
cusj-7408	9	1	as	as	SCONJ
cusj-7408	9	2	daily	daily	ADJ
cusj-7408	9	3	feeding	feeding	NOUN
cusj-7408	9	4	rhythm	rhythm	NOUN
cusj-7408	9	5	entrains	entrain	VERB
cusj-7408	9	6	diurnal	diurnal	ADJ
cusj-7408	9	7	fluctuations	fluctuation	NOUN
cusj-7408	9	8	in	in	ADP
cusj-7408	9	9	microbiome	microbiome	NOUN
cusj-7408	9	10	,	,	PUNCT
cusj-7408	9	11	we	we	PRON
cusj-7408	9	12	have	have	AUX
cusj-7408	9	13	set	set	VERB
cusj-7408	9	14	out	out	ADP
cusj-7408	9	15	to	to	PART
cusj-7408	9	16	measure	measure	VERB
cusj-7408	9	17	how	how	SCONJ
cusj-7408	9	18	epithelial	epithelial	ADJ
cusj-7408	9	19	barrier	barrier	NOUN
cusj-7408	9	20	permeability	permeability	NOUN
cusj-7408	9	21	disrupts	disrupt	VERB
cusj-7408	9	22	the	the	DET
cusj-7408	9	23	clock	clock	NOUN
cusj-7408	9	24	.	.	PUNCT
cusj-7408	10	1	we	we	PRON
cusj-7408	10	2	have	have	AUX
cusj-7408	10	3	discovered	discover	VERB
cusj-7408	10	4	that	that	SCONJ
cusj-7408	10	5	the	the	DET
cusj-7408	10	6	permeability	permeability	NOUN
cusj-7408	10	7	of	of	ADP
cusj-7408	10	8	the	the	DET
cusj-7408	10	9	intestinal	intestinal	ADJ
cusj-7408	10	10	epithelial	epithelial	ADJ
cusj-7408	10	11	barrier	barrier	NOUN
cusj-7408	10	12	exhibits	exhibit	VERB
cusj-7408	10	13	circadian	circadian	ADJ
cusj-7408	10	14	rhythms	rhythm	NOUN
cusj-7408	10	15	in	in	ADP
cusj-7408	10	16	mice	mouse	NOUN
cusj-7408	10	17	.	.	PUNCT
cusj-7408	11	1	disruption	disruption	NOUN
cusj-7408	11	2	of	of	ADP
cusj-7408	11	3	these	these	DET
cusj-7408	11	4	rhythms	rhythm	NOUN
cusj-7408	11	5	,	,	PUNCT
cusj-7408	11	6	through	through	ADP
cusj-7408	11	7	jet	jet	NOUN
cusj-7408	11	8	lag	lag	NOUN
cusj-7408	11	9	or	or	CCONJ
cusj-7408	11	10	genetic	genetic	ADJ
cusj-7408	11	11	deficiencies	deficiency	NOUN
cusj-7408	11	12	in	in	ADP
cusj-7408	11	13	circadian	circadian	ADJ
cusj-7408	11	14	machinery	machinery	NOUN
cusj-7408	11	15	,	,	PUNCT
cusj-7408	11	16	alters	alter	VERB
cusj-7408	11	17	epithelial	epithelial	ADJ
cusj-7408	11	18	barrier	barrier	NOUN
cusj-7408	11	19	integrity	integrity	NOUN
cusj-7408	11	20	.	.	PUNCT
cusj-7408	12	1	together	together	ADV
cusj-7408	12	2	,	,	PUNCT
cusj-7408	12	3	these	these	DET
cusj-7408	12	4	findings	finding	NOUN
cusj-7408	12	5	provide	provide	VERB
cusj-7408	12	6	evidence	evidence	NOUN
cusj-7408	12	7	that	that	SCONJ
cusj-7408	12	8	disruptions	disruption	NOUN
cusj-7408	12	9	in	in	ADP
cusj-7408	12	10	circadian	circadian	ADJ
cusj-7408	12	11	rhythms	rhythm	NOUN
cusj-7408	12	12	as	as	ADV
cusj-7408	12	13	well	well	ADV
cusj-7408	12	14	as	as	ADP
cusj-7408	12	15	alterations	alteration	NOUN
cusj-7408	12	16	in	in	ADP
cusj-7408	12	17	microbiome	microbiome	ADJ
cusj-7408	12	18	composition	composition	NOUN
cusj-7408	12	19	have	have	AUX
cusj-7408	12	20	direct	direct	ADJ
cusj-7408	12	21	consequences	consequence	NOUN
cusj-7408	12	22	in	in	ADP
cusj-7408	12	23	intestinal	intestinal	ADJ
cusj-7408	12	24	permeability	permeability	NOUN
cusj-7408	12	25	,	,	PUNCT
cusj-7408	12	26	and	and	CCONJ
cusj-7408	12	27	that	that	DET
cusj-7408	12	28	microbiome	microbiome	NOUN
cusj-7408	12	29	might	might	AUX
cusj-7408	12	30	serve	serve	VERB
cusj-7408	12	31	as	as	ADP
cusj-7408	12	32	a	a	DET
cusj-7408	12	33	tool	tool	NOUN
cusj-7408	12	34	in	in	ADP
cusj-7408	12	35	regulating	regulate	VERB
cusj-7408	12	36	epithelium	epithelium	ADJ
cusj-7408	12	37	permeability	permeability	NOUN
cusj-7408	12	38	.	.	PUNCT
cusj-7408	13	1	introduction	introduction	NOUN
cusj-7408	13	2	the	the	DET
cusj-7408	13	3	human	human	ADJ
cusj-7408	13	4	body	body	NOUN
cusj-7408	13	5	is	be	AUX
cusj-7408	13	6	colonized	colonize	VERB
cusj-7408	13	7	by	by	ADP
cusj-7408	13	8	a	a	DET
cusj-7408	13	9	complex	complex	ADJ
cusj-7408	13	10	community	community	NOUN
cusj-7408	13	11	of	of	ADP
cusj-7408	13	12	microorganisms	microorganism	NOUN
cusj-7408	13	13	,	,	PUNCT
cusj-7408	13	14	termed	term	VERB
cusj-7408	13	15	the	the	DET
cusj-7408	13	16	human	human	ADJ
cusj-7408	13	17	microbiome	microbiome	NOUN
cusj-7408	13	18	,	,	PUNCT
cusj-7408	13	19	that	that	PRON
cusj-7408	13	20	includes	include	VERB
cusj-7408	13	21	bacteria	bacteria	NOUN
cusj-7408	13	22	,	,	PUNCT
cusj-7408	13	23	archaea	archaea	NOUN
cusj-7408	13	24	,	,	PUNCT
cusj-7408	13	25	viruses	virus	NOUN
cusj-7408	13	26	and	and	CCONJ
cusj-7408	13	27	fungi	fungus	NOUN
cusj-7408	13	28	[	[	X
cusj-7408	13	29	1	1	NUM
cusj-7408	13	30	]	]	PUNCT
cusj-7408	13	31	.	.	PUNCT
cusj-7408	14	1	this	this	DET
cusj-7408	14	2	ecological	ecological	ADJ
cusj-7408	14	3	community	community	NOUN
cusj-7408	14	4	exists	exist	VERB
cusj-7408	14	5	primarily	primarily	ADV
cusj-7408	14	6	on	on	ADP
cusj-7408	14	7	mucosal	mucosal	ADJ
cusj-7408	14	8	sites	site	NOUN
cusj-7408	14	9	,	,	PUNCT
cusj-7408	14	10	like	like	ADP
cusj-7408	14	11	the	the	DET
cusj-7408	14	12	gastrointestinal	gastrointestinal	ADJ
cusj-7408	14	13	tract	tract	NOUN
cusj-7408	14	14	,	,	PUNCT
cusj-7408	14	15	skin	skin	NOUN
cusj-7408	14	16	,	,	PUNCT
cusj-7408	14	17	lungs	lung	NOUN
cusj-7408	14	18	and	and	CCONJ
cusj-7408	14	19	urogenital	urogenital	ADJ
cusj-7408	14	20	system	system	NOUN
cusj-7408	14	21	[	[	X
cusj-7408	14	22	2	2	NUM
cusj-7408	14	23	]	]	PUNCT
cusj-7408	14	24	.	.	PUNCT
cusj-7408	15	1	this	this	DET
cusj-7408	15	2	community	community	NOUN
cusj-7408	15	3	is	be	AUX
cusj-7408	15	4	such	such	ADJ
cusj-7408	15	5	where	where	SCONJ
cusj-7408	15	6	the	the	DET
cusj-7408	15	7	microbiome	microbiome	ADJ
cusj-7408	15	8	bacteria	bacteria	NOUN
cusj-7408	15	9	outnumber	outnumber	VERB
cusj-7408	15	10	eukaryotic	eukaryotic	ADJ
cusj-7408	15	11	cells	cell	NOUN
cusj-7408	15	12	in	in	ADP
cusj-7408	15	13	the	the	DET
cusj-7408	15	14	entire	entire	ADJ
cusj-7408	15	15	human	human	ADJ
cusj-7408	15	16	body	body	NOUN
cusj-7408	15	17	1.3:1	1.3:1	NUM
cusj-7408	16	1	[	[	X
cusj-7408	16	2	3	3	NUM
cusj-7408	16	3	]	]	PUNCT
cusj-7408	16	4	.	.	PUNCT
cusj-7408	17	1	the	the	DET
cusj-7408	17	2	microbiota	microbiota	NOUN
cusj-7408	17	3	is	be	AUX
cusj-7408	17	4	responsible	responsible	ADJ
cusj-7408	17	5	for	for	ADP
cusj-7408	17	6	the	the	DET
cusj-7408	17	7	regulation	regulation	NOUN
cusj-7408	17	8	of	of	ADP
cusj-7408	17	9	many	many	ADJ
cusj-7408	17	10	physiological	physiological	ADJ
cusj-7408	17	11	processes	process	NOUN
cusj-7408	17	12	,	,	PUNCT
cusj-7408	17	13	including	include	VERB
cusj-7408	17	14	digestion	digestion	NOUN
cusj-7408	17	15	,	,	PUNCT
cusj-7408	17	16	absorption	absorption	NOUN
cusj-7408	17	17	[	[	X
cusj-7408	17	18	4	4	NUM
cusj-7408	17	19	]	]	PUNCT
cusj-7408	17	20	,	,	PUNCT
cusj-7408	17	21	host	host	NOUN
cusj-7408	17	22	metabolism	metabolism	NOUN
cusj-7408	18	1	[	[	X
cusj-7408	18	2	5	5	NUM
cusj-7408	18	3	]	]	PUNCT
cusj-7408	18	4	,	,	PUNCT
cusj-7408	18	5	the	the	DET
cusj-7408	18	6	maturation	maturation	NOUN
cusj-7408	18	7	and	and	CCONJ
cusj-7408	18	8	function	function	NOUN
cusj-7408	18	9	of	of	ADP
cusj-7408	18	10	the	the	DET
cusj-7408	18	11	immune	immune	ADJ
cusj-7408	18	12	system	system	NOUN
cusj-7408	18	13	[	[	X
cusj-7408	18	14	4	4	NUM
cusj-7408	18	15	]	]	PUNCT
cusj-7408	18	16	,	,	PUNCT
cusj-7408	18	17	and	and	CCONJ
cusj-7408	18	18	even	even	ADV
cusj-7408	18	19	host	host	NOUN
cusj-7408	18	20	behavior	behavior	NOUN
cusj-7408	18	21	and	and	CCONJ
cusj-7408	18	22	cognitive	cognitive	ADJ
cusj-7408	18	23	function	function	NOUN
cusj-7408	18	24	[	[	X
cusj-7408	18	25	6	6	NUM
cusj-7408	18	26	]	]	PUNCT
cusj-7408	18	27	.	.	PUNCT
cusj-7408	19	1	however	however	ADV
cusj-7408	19	2	,	,	PUNCT
cusj-7408	19	3	when	when	SCONJ
cusj-7408	19	4	the	the	DET
cusj-7408	19	5	balanced	balanced	ADJ
cusj-7408	19	6	microbial	microbial	ADJ
cusj-7408	19	7	composition	composition	NOUN
cusj-7408	19	8	is	be	AUX
cusj-7408	19	9	disrupted	disrupt	VERB
cusj-7408	19	10	,	,	PUNCT
cusj-7408	19	11	dysbiosis	dysbiosis	NOUN
cusj-7408	19	12	can	can	AUX
cusj-7408	19	13	cause	cause	VERB
cusj-7408	19	14	intestinal	intestinal	ADJ
cusj-7408	19	15	diseases	disease	NOUN
cusj-7408	19	16	[	[	X
cusj-7408	19	17	7	7	NUM
cusj-7408	19	18	]	]	PUNCT
cusj-7408	19	19	.	.	PUNCT
cusj-7408	20	1	modulating	modulate	VERB
cusj-7408	20	2	©	©	PROPN
cusj-7408	20	3	2021	2021	NUM
cusj-7408	20	4	pinker	pinker	NOUN
cusj-7408	20	5	,	,	PUNCT
cusj-7408	20	6	tuganbaev	tuganbaev	NOUN
cusj-7408	20	7	.	.	PUNCT
cusj-7408	21	1	this	this	PRON
cusj-7408	21	2	is	be	AUX
cusj-7408	21	3	an	an	DET
cusj-7408	21	4	open	open	ADJ
cusj-7408	21	5	access	access	NOUN
cusj-7408	21	6	article	article	NOUN
cusj-7408	21	7	distributed	distribute	VERB
cusj-7408	21	8	under	under	ADP
cusj-7408	21	9	the	the	DET
cusj-7408	21	10	terms	term	NOUN
cusj-7408	21	11	of	of	ADP
cusj-7408	21	12	the	the	DET
cusj-7408	21	13	creative	creative	ADJ
cusj-7408	21	14	commons	common	NOUN
cusj-7408	21	15	attribution	attribution	NOUN
cusj-7408	21	16	license	license	NOUN
cusj-7408	21	17	,	,	PUNCT
cusj-7408	21	18	which	which	PRON
cusj-7408	21	19	permits	permit	VERB
cusj-7408	21	20	the	the	DET
cusj-7408	21	21	user	user	NOUN
cusj-7408	21	22	to	to	PART
cusj-7408	21	23	copy	copy	VERB
cusj-7408	21	24	,	,	PUNCT
cusj-7408	21	25	distribute	distribute	VERB
cusj-7408	21	26	,	,	PUNCT
cusj-7408	21	27	and	and	CCONJ
cusj-7408	21	28	transmit	transmit	VERB
cusj-7408	21	29	the	the	DET
cusj-7408	21	30	work	work	NOUN
cusj-7408	21	31	provided	provide	VERB
cusj-7408	21	32	that	that	SCONJ
cusj-7408	21	33	the	the	DET
cusj-7408	21	34	original	original	ADJ
cusj-7408	21	35	authors	author	NOUN
cusj-7408	21	36	and	and	CCONJ
cusj-7408	21	37	source	source	NOUN
cusj-7408	21	38	are	be	AUX
cusj-7408	21	39	credited	credit	VERB
cusj-7408	21	40	.	.	PUNCT
cusj-7408	22	1	keywords	keyword	NOUN
cusj-7408	22	2	:	:	PUNCT
cusj-7408	22	3	circadian	circadian	ADJ
cusj-7408	22	4	rhythms	rhythm	NOUN
cusj-7408	22	5	,	,	PUNCT
cusj-7408	22	6	intestinal	intestinal	ADJ
cusj-7408	22	7	permeability	permeability	NOUN
cusj-7408	22	8	,	,	PUNCT
cusj-7408	22	9	microbiome	microbiome	ADJ
cusj-7408	22	10	7	7	NUM
cusj-7408	22	11	columbia	columbia	PROPN
cusj-7408	22	12	undergraduate	undergraduate	PROPN
cusj-7408	22	13	science	science	PROPN
cusj-7408	22	14	journal	journal	PROPN
cusj-7408	22	15	vol	vol	NOUN
cusj-7408	22	16	.	.	PROPN
cusj-7408	22	17	15	15	NUM
cusj-7408	22	18	,	,	PUNCT
cusj-7408	22	19	2021	2021	NUM
cusj-7408	22	20	pinker	pinker	PROPN
cusj-7408	22	21	et	et	PROPN
cusj-7408	22	22	.	.	PUNCT
cusj-7408	23	1	al	al	PROPN
cusj-7408	23	2	.	.	PUNCT
cusj-7408	24	1	the	the	DET
cusj-7408	24	2	microbiome	microbiome	NOUN
cusj-7408	24	3	through	through	ADP
cusj-7408	24	4	the	the	DET
cusj-7408	24	5	diet	diet	NOUN
cusj-7408	24	6	is	be	AUX
cusj-7408	24	7	one	one	NUM
cusj-7408	24	8	way	way	NOUN
cusj-7408	24	9	to	to	PART
cusj-7408	24	10	induce	induce	VERB
cusj-7408	24	11	dysbiosis	dysbiosis	NOUN
cusj-7408	24	12	.	.	PUNCT
cusj-7408	25	1	treatment	treatment	NOUN
cusj-7408	25	2	with	with	ADP
cusj-7408	25	3	high	high	ADJ
cusj-7408	25	4	-	-	PUNCT
cusj-7408	25	5	fat	fat	NOUN
cusj-7408	25	6	diet	diet	NOUN
cusj-7408	25	7	(	(	PUNCT
cusj-7408	25	8	hfd	hfd	PROPN
cusj-7408	25	9	)	)	PUNCT
cusj-7408	25	10	,	,	PUNCT
cusj-7408	25	11	containing	contain	VERB
cusj-7408	25	12	60	60	NUM
cusj-7408	25	13	%	%	NOUN
cusj-7408	25	14	of	of	ADP
cusj-7408	25	15	caloric	caloric	ADJ
cusj-7408	25	16	energy	energy	NOUN
cusj-7408	25	17	derived	derive	VERB
cusj-7408	25	18	from	from	ADP
cusj-7408	25	19	fat	fat	ADJ
cusj-7408	25	20	(	(	PUNCT
cusj-7408	25	21	a	a	DET
cusj-7408	25	22	model	model	NOUN
cusj-7408	25	23	of	of	ADP
cusj-7408	25	24	a	a	DET
cusj-7408	25	25	“	"	PUNCT
cusj-7408	25	26	western	western	ADJ
cusj-7408	25	27	diet	diet	NOUN
cusj-7408	25	28	”	"	PUNCT
cusj-7408	25	29	)	)	PUNCT
cusj-7408	25	30	,	,	PUNCT
cusj-7408	25	31	is	be	AUX
cusj-7408	25	32	one	one	NUM
cusj-7408	25	33	such	such	ADJ
cusj-7408	25	34	example	example	NOUN
cusj-7408	25	35	where	where	SCONJ
cusj-7408	25	36	the	the	DET
cusj-7408	25	37	balanced	balanced	ADJ
cusj-7408	25	38	gut	gut	NOUN
cusj-7408	25	39	microbial	microbial	ADJ
cusj-7408	25	40	community	community	NOUN
cusj-7408	25	41	is	be	AUX
cusj-7408	25	42	altered	alter	VERB
cusj-7408	25	43	to	to	ADP
cusj-7408	25	44	the	the	DET
cusj-7408	25	45	point	point	NOUN
cusj-7408	25	46	of	of	ADP
cusj-7408	25	47	dysbiosis	dysbiosis	NOUN
cusj-7408	25	48	resulting	result	VERB
cusj-7408	25	49	in	in	ADP
cusj-7408	25	50	metabolic	metabolic	ADJ
cusj-7408	25	51	dysfunction	dysfunction	NOUN
cusj-7408	25	52	consequently	consequently	ADV
cusj-7408	25	53	inducing	induce	VERB
cusj-7408	25	54	disease	disease	NOUN
cusj-7408	25	55	,	,	PUNCT
cusj-7408	25	56	such	such	ADJ
cusj-7408	25	57	as	as	ADP
cusj-7408	25	58	obesity	obesity	NOUN
cusj-7408	25	59	and	and	CCONJ
cusj-7408	25	60	type	type	NOUN
cusj-7408	25	61	2	2	NUM
cusj-7408	25	62	diabetes	diabetes	NOUN
cusj-7408	25	63	as	as	ADV
cusj-7408	25	64	well	well	ADV
cusj-7408	25	65	as	as	ADP
cusj-7408	25	66	exacerbating	exacerbate	VERB
cusj-7408	25	67	inflammatory	inflammatory	ADJ
cusj-7408	25	68	bowel	bowel	NOUN
cusj-7408	25	69	diseases	disease	NOUN
cusj-7408	25	70	(	(	PUNCT
cusj-7408	25	71	ibd	ibd	NOUN
cusj-7408	25	72	)	)	PUNCT
cusj-7408	26	1	[	[	X
cusj-7408	26	2	7	7	NUM
cusj-7408	26	3	]	]	PUNCT
cusj-7408	26	4	.	.	PUNCT
cusj-7408	27	1	but	but	CCONJ
cusj-7408	27	2	,	,	PUNCT
cusj-7408	27	3	when	when	SCONJ
cusj-7408	27	4	treated	treat	VERB
cusj-7408	27	5	with	with	ADP
cusj-7408	27	6	broad	broad	ADJ
cusj-7408	27	7	-	-	PUNCT
cusj-7408	27	8	spectrum	spectrum	NOUN
cusj-7408	27	9	antibiotics	antibiotic	NOUN
cusj-7408	27	10	,	,	PUNCT
cusj-7408	27	11	obesity	obesity	NOUN
cusj-7408	27	12	and	and	CCONJ
cusj-7408	27	13	glucose	glucose	NOUN
cusj-7408	27	14	intolerance	intolerance	NOUN
cusj-7408	27	15	in	in	ADP
cusj-7408	27	16	mice	mouse	NOUN
cusj-7408	27	17	fed	feed	VERB
cusj-7408	27	18	with	with	ADP
cusj-7408	27	19	hfd	hfd	PROPN
cusj-7408	27	20	is	be	AUX
cusj-7408	27	21	abrogated	abrogate	VERB
cusj-7408	27	22	[	[	X
cusj-7408	27	23	8	8	NUM
cusj-7408	27	24	]	]	PUNCT
cusj-7408	27	25	.	.	PUNCT
cusj-7408	28	1	previous	previous	ADJ
cusj-7408	28	2	studies	study	NOUN
cusj-7408	28	3	show	show	VERB
cusj-7408	28	4	,	,	PUNCT
cusj-7408	28	5	that	that	SCONJ
cusj-7408	28	6	when	when	SCONJ
cusj-7408	28	7	microbiome	microbiome	ADJ
cusj-7408	28	8	from	from	ADP
cusj-7408	28	9	mice	mouse	NOUN
cusj-7408	28	10	fed	fed	PROPN
cusj-7408	28	11	hfd	hfd	PROPN
cusj-7408	28	12	were	be	AUX
cusj-7408	28	13	transplanted	transplant	VERB
cusj-7408	28	14	into	into	ADP
cusj-7408	28	15	germ	germ	NOUN
cusj-7408	28	16	-	-	PUNCT
cusj-7408	28	17	free	free	ADJ
cusj-7408	28	18	mice	mouse	NOUN
cusj-7408	28	19	(	(	PUNCT
cusj-7408	28	20	gf	gf	NOUN
cusj-7408	28	21	:	:	PUNCT
cusj-7408	28	22	free	free	ADJ
cusj-7408	28	23	of	of	ADP
cusj-7408	28	24	microorganisms	microorganism	NOUN
cusj-7408	28	25	)	)	PUNCT
cusj-7408	28	26	significantly	significantly	ADV
cusj-7408	28	27	more	more	ADJ
cusj-7408	28	28	weight	weight	NOUN
cusj-7408	28	29	is	be	AUX
cusj-7408	28	30	put	put	VERB
cusj-7408	28	31	on	on	ADP
cusj-7408	28	32	by	by	ADP
cusj-7408	28	33	these	these	DET
cusj-7408	28	34	mice	mouse	NOUN
cusj-7408	28	35	compared	compare	VERB
cusj-7408	28	36	to	to	ADP
cusj-7408	28	37	gf	gf	NOUN
cusj-7408	28	38	mice	mouse	NOUN
cusj-7408	28	39	transplanted	transplant	VERB
cusj-7408	28	40	with	with	ADP
cusj-7408	28	41	microbiome	microbiome	NOUN
cusj-7408	28	42	from	from	ADP
cusj-7408	28	43	lean	lean	ADJ
cusj-7408	28	44	donor	donor	NOUN
cusj-7408	28	45	mice	mouse	NOUN
cusj-7408	28	46	fed	fed	PROPN
cusj-7408	28	47	nc	nc	PROPN
cusj-7408	28	48	(	(	PUNCT
cusj-7408	28	49	normal	normal	ADJ
cusj-7408	28	50	chow	chow	NOUN
cusj-7408	28	51	)	)	PUNCT
cusj-7408	29	1	[	[	X
cusj-7408	29	2	9	9	NUM
cusj-7408	29	3	]	]	PUNCT
cusj-7408	29	4	.	.	PUNCT
cusj-7408	29	5	additionally	additionally	ADV
cusj-7408	29	6	,	,	PUNCT
cusj-7408	29	7	gf	gf	NOUN
cusj-7408	29	8	condition	condition	NOUN
cusj-7408	29	9	in	in	ADP
cusj-7408	29	10	mice	mouse	NOUN
cusj-7408	29	11	causes	cause	VERB
cusj-7408	29	12	significant	significant	ADJ
cusj-7408	29	13	immune	immune	ADJ
cusj-7408	29	14	system	system	NOUN
cusj-7408	29	15	deficiency	deficiency	NOUN
cusj-7408	29	16	[	[	X
cusj-7408	29	17	7	7	NUM
cusj-7408	29	18	]	]	PUNCT
cusj-7408	29	19	.	.	PUNCT
cusj-7408	30	1	tools	tool	NOUN
cusj-7408	30	2	like	like	ADP
cusj-7408	30	3	gnotobiotic	gnotobiotic	ADJ
cusj-7408	30	4	animal	animal	NOUN
cusj-7408	30	5	models	model	NOUN
cusj-7408	30	6	(	(	PUNCT
cusj-7408	30	7	gf	gf	NOUN
cusj-7408	30	8	mice	mouse	NOUN
cusj-7408	30	9	)	)	PUNCT
cusj-7408	30	10	and	and	CCONJ
cusj-7408	30	11	broad	broad	ADJ
cusj-7408	30	12	-	-	PUNCT
cusj-7408	30	13	spectrum	spectrum	NOUN
cusj-7408	30	14	antibiotics	antibiotic	NOUN
cusj-7408	30	15	,	,	PUNCT
cusj-7408	30	16	have	have	AUX
cusj-7408	30	17	enabled	enable	VERB
cusj-7408	30	18	the	the	DET
cusj-7408	30	19	discovery	discovery	NOUN
cusj-7408	30	20	that	that	PRON
cusj-7408	30	21	microbiota	microbiota	NOUN
cusj-7408	30	22	contributions	contribution	NOUN
cusj-7408	30	23	to	to	ADP
cusj-7408	30	24	health	health	NOUN
cusj-7408	30	25	and	and	CCONJ
cusj-7408	30	26	disease	disease	NOUN
cusj-7408	30	27	span	span	VERB
cusj-7408	30	28	multiple	multiple	ADJ
cusj-7408	30	29	organ	organ	NOUN
cusj-7408	30	30	systems	system	NOUN
cusj-7408	30	31	.	.	PUNCT
cusj-7408	31	1	it	it	PRON
cusj-7408	31	2	has	have	AUX
cusj-7408	31	3	previously	previously	ADV
cusj-7408	31	4	been	be	AUX
cusj-7408	31	5	shown	show	VERB
cusj-7408	31	6	that	that	SCONJ
cusj-7408	31	7	the	the	DET
cusj-7408	31	8	mammalian	mammalian	ADJ
cusj-7408	31	9	intestinal	intestinal	ADJ
cusj-7408	31	10	microbiota	microbiota	NOUN
cusj-7408	31	11	composition	composition	NOUN
cusj-7408	31	12	exhibits	exhibit	VERB
cusj-7408	31	13	diurnal	diurnal	ADJ
cusj-7408	31	14	oscillations	oscillation	NOUN
cusj-7408	31	15	both	both	CCONJ
cusj-7408	31	16	in	in	ADP
cusj-7408	31	17	terms	term	NOUN
cusj-7408	31	18	of	of	ADP
cusj-7408	31	19	its	its	PRON
cusj-7408	31	20	composition	composition	NOUN
cusj-7408	31	21	and	and	CCONJ
cusj-7408	31	22	metabolic	metabolic	NOUN
cusj-7408	31	23	activity	activity	NOUN
cusj-7408	31	24	[	[	X
cusj-7408	31	25	8	8	NUM
cusj-7408	31	26	]	]	PUNCT
cusj-7408	31	27	.	.	PUNCT
cusj-7408	32	1	the	the	DET
cusj-7408	32	2	circadian	circadian	ADJ
cusj-7408	32	3	clock	clock	NOUN
cusj-7408	32	4	is	be	AUX
cusj-7408	32	5	the	the	DET
cusj-7408	32	6	top	top	NOUN
cusj-7408	32	7	of	of	ADP
cusj-7408	32	8	a	a	DET
cusj-7408	32	9	hierarchical	hierarchical	ADJ
cusj-7408	32	10	internal	internal	ADJ
cusj-7408	32	11	clock	clock	NOUN
cusj-7408	32	12	system	system	NOUN
cusj-7408	32	13	that	that	PRON
cusj-7408	32	14	is	be	AUX
cusj-7408	32	15	responsible	responsible	ADJ
cusj-7408	32	16	for	for	ADP
cusj-7408	32	17	the	the	DET
cusj-7408	32	18	circadian	circadian	ADJ
cusj-7408	32	19	biological	biological	ADJ
cusj-7408	32	20	processes	process	NOUN
cusj-7408	32	21	ranging	range	VERB
cusj-7408	32	22	from	from	ADP
cusj-7408	32	23	dictating	dictate	VERB
cusj-7408	32	24	the	the	DET
cusj-7408	32	25	rhythmic	rhythmic	ADJ
cusj-7408	32	26	gene	gene	NOUN
cusj-7408	32	27	expression	expression	NOUN
cusj-7408	32	28	in	in	ADP
cusj-7408	32	29	organs	organ	NOUN
cusj-7408	32	30	to	to	PART
cusj-7408	32	31	behavior	behavior	VERB
cusj-7408	32	32	,	,	PUNCT
cusj-7408	32	33	metabolism	metabolism	NOUN
cusj-7408	32	34	and	and	CCONJ
cusj-7408	32	35	immunity	immunity	NOUN
cusj-7408	32	36	[	[	X
cusj-7408	32	37	10][11	10][11	X
cusj-7408	32	38	]	]	PUNCT
cusj-7408	32	39	.	.	PUNCT
cusj-7408	33	1	when	when	SCONJ
cusj-7408	33	2	working	work	VERB
cusj-7408	33	3	with	with	ADP
cusj-7408	33	4	circadian	circadian	ADJ
cusj-7408	33	5	rhythms	rhythm	NOUN
cusj-7408	33	6	,	,	PUNCT
cusj-7408	33	7	scientists	scientist	NOUN
cusj-7408	33	8	devised	devise	VERB
cusj-7408	33	9	zeitgeber	zeitgeber	PROPN
cusj-7408	33	10	times	time	NOUN
cusj-7408	33	11	(	(	PUNCT
cusj-7408	33	12	zt	zt	PROPN
cusj-7408	33	13	)	)	PUNCT
cusj-7408	33	14	which	which	PRON
cusj-7408	33	15	measure	measure	VERB
cusj-7408	33	16	time	time	NOUN
cusj-7408	33	17	on	on	ADP
cusj-7408	33	18	a	a	DET
cusj-7408	33	19	24	24	NUM
cusj-7408	33	20	-	-	PUNCT
cusj-7408	33	21	hour	hour	NOUN
cusj-7408	33	22	light	light	ADJ
cusj-7408	33	23	/	/	SYM
cusj-7408	33	24	dark	dark	ADJ
cusj-7408	33	25	cycle	cycle	NOUN
cusj-7408	33	26	,	,	PUNCT
cusj-7408	33	27	so	so	ADV
cusj-7408	33	28	zt12	zt12	PROPN
cusj-7408	33	29	and	and	CCONJ
cusj-7408	33	30	zt0	zt0	NOUN
cusj-7408	33	31	denote	denote	VERB
cusj-7408	33	32	“	"	PUNCT
cusj-7408	33	33	dusk	dusk	NOUN
cusj-7408	33	34	”	"	PUNCT
cusj-7408	33	35	and	and	CCONJ
cusj-7408	33	36	dawn	dawn	NOUN
cusj-7408	33	37	”	"	PUNCT
cusj-7408	33	38	,	,	PUNCT
cusj-7408	33	39	respectively	respectively	ADV
cusj-7408	33	40	.	.	PUNCT
cusj-7408	34	1	the	the	DET
cusj-7408	34	2	molecular	molecular	ADJ
cusj-7408	34	3	mechanisms	mechanism	NOUN
cusj-7408	34	4	behind	behind	ADP
cusj-7408	34	5	the	the	DET
cusj-7408	34	6	circadian	circadian	ADJ
cusj-7408	34	7	clocks	clock	NOUN
cusj-7408	34	8	in	in	ADP
cusj-7408	34	9	mammals	mammal	NOUN
cusj-7408	34	10	is	be	AUX
cusj-7408	34	11	orchestrated	orchestrate	VERB
cusj-7408	34	12	under	under	ADP
cusj-7408	34	13	a	a	DET
cusj-7408	34	14	transcriptional	transcriptional	ADJ
cusj-7408	34	15	autoregulatory	autoregulatory	NOUN
cusj-7408	34	16	feedback	feedback	NOUN
cusj-7408	34	17	loop	loop	NOUN
cusj-7408	34	18	comprised	comprise	VERB
cusj-7408	34	19	of	of	ADP
cusj-7408	34	20	the	the	DET
cusj-7408	34	21	‘	'	PUNCT
cusj-7408	34	22	core	core	NOUN
cusj-7408	34	23	’	'	PUNCT
cusj-7408	34	24	clock	clock	NOUN
cusj-7408	34	25	genes	gene	NOUN
cusj-7408	34	26	clock	clock	NOUN
cusj-7408	34	27	and	and	CCONJ
cusj-7408	34	28	bmal1	bmal1	VERB
cusj-7408	34	29	,	,	PUNCT
cusj-7408	34	30	responsible	responsible	ADJ
cusj-7408	34	31	for	for	ADP
cusj-7408	34	32	encoding	encode	VERB
cusj-7408	34	33	activators	activator	NOUN
cusj-7408	34	34	,	,	PUNCT
cusj-7408	34	35	and	and	CCONJ
cusj-7408	34	36	per1	per1	NOUN
cusj-7408	34	37	,	,	PUNCT
cusj-7408	34	38	per2	per2	NOUN
cusj-7408	34	39	,	,	PUNCT
cusj-7408	34	40	cry1	cry1	NOUN
cusj-7408	34	41	and	and	CCONJ
cusj-7408	34	42	cry2	cry2	PROPN
cusj-7408	34	43	,	,	PUNCT
cusj-7408	34	44	responsible	responsible	ADJ
cusj-7408	34	45	for	for	ADP
cusj-7408	34	46	encoding	encode	VERB
cusj-7408	34	47	repressors	repressor	NOUN
cusj-7408	34	48	[	[	X
cusj-7408	34	49	12	12	NUM
cusj-7408	34	50	]	]	PUNCT
cusj-7408	34	51	.	.	PUNCT
cusj-7408	35	1	a	a	DET
cusj-7408	35	2	disruption	disruption	NOUN
cusj-7408	35	3	of	of	ADP
cusj-7408	35	4	the	the	DET
cusj-7408	35	5	circadian	circadian	ADJ
cusj-7408	35	6	clock	clock	NOUN
cusj-7408	35	7	in	in	ADP
cusj-7408	35	8	humans	human	NOUN
cusj-7408	35	9	,	,	PUNCT
cusj-7408	35	10	environmentally	environmentally	ADV
cusj-7408	35	11	or	or	CCONJ
cusj-7408	35	12	by	by	ADP
cusj-7408	35	13	gene	gene	NOUN
cusj-7408	35	14	deficiency	deficiency	NOUN
cusj-7408	35	15	,	,	PUNCT
cusj-7408	35	16	is	be	AUX
cusj-7408	35	17	associated	associate	VERB
cusj-7408	35	18	with	with	ADP
cusj-7408	35	19	an	an	DET
cusj-7408	35	20	array	array	NOUN
cusj-7408	35	21	of	of	ADP
cusj-7408	35	22	diseases	disease	NOUN
cusj-7408	35	23	such	such	ADJ
cusj-7408	35	24	as	as	ADP
cusj-7408	35	25	,	,	PUNCT
cusj-7408	35	26	obesity	obesity	NOUN
cusj-7408	35	27	and	and	CCONJ
cusj-7408	35	28	diabetes	diabetes	NOUN
cusj-7408	35	29	[	[	X
cusj-7408	35	30	13	13	NUM
cusj-7408	35	31	]	]	PUNCT
cusj-7408	36	1	[	[	X
cusj-7408	36	2	14	14	NUM
cusj-7408	36	3	]	]	PUNCT
cusj-7408	36	4	,	,	PUNCT
cusj-7408	36	5	cancer	cancer	NOUN
cusj-7408	36	6	[	[	X
cusj-7408	36	7	15	15	NUM
cusj-7408	36	8	]	]	X
cusj-7408	36	9	,	,	PUNCT
cusj-7408	36	10	cardiovascular	cardiovascular	ADJ
cusj-7408	36	11	disease	disease	NOUN
cusj-7408	36	12	[	[	X
cusj-7408	36	13	16	16	NUM
cusj-7408	36	14	]	]	PUNCT
cusj-7408	36	15	,	,	PUNCT
cusj-7408	36	16	ibd	ibd	NOUN
cusj-7408	36	17	(	(	PUNCT
cusj-7408	36	18	inflammatory	inflammatory	ADJ
cusj-7408	36	19	bowel	bowel	NOUN
cusj-7408	36	20	disease	disease	NOUN
cusj-7408	36	21	)	)	PUNCT
cusj-7408	36	22	exacerbation	exacerbation	NOUN
cusj-7408	36	23	[	[	X
cusj-7408	36	24	17	17	NUM
cusj-7408	36	25	]	]	PUNCT
cusj-7408	36	26	and	and	CCONJ
cusj-7408	36	27	susceptibility	susceptibility	NOUN
cusj-7408	36	28	to	to	ADP
cusj-7408	36	29	infection	infection	NOUN
cusj-7408	36	30	.	.	PUNCT
cusj-7408	37	1	one	one	NUM
cusj-7408	37	2	common	common	ADJ
cusj-7408	37	3	feature	feature	NOUN
cusj-7408	37	4	among	among	ADP
cusj-7408	37	5	the	the	DET
cusj-7408	37	6	diseases	disease	NOUN
cusj-7408	37	7	associated	associate	VERB
cusj-7408	37	8	with	with	ADP
cusj-7408	37	9	circadian	circadian	ADJ
cusj-7408	37	10	rhythm	rhythm	NOUN
cusj-7408	37	11	disruption	disruption	NOUN
cusj-7408	37	12	,	,	PUNCT
cusj-7408	37	13	is	be	AUX
cusj-7408	37	14	that	that	SCONJ
cusj-7408	37	15	they	they	PRON
cusj-7408	37	16	appear	appear	VERB
cusj-7408	37	17	to	to	PART
cusj-7408	37	18	be	be	AUX
cusj-7408	37	19	triggered	trigger	VERB
cusj-7408	37	20	or	or	CCONJ
cusj-7408	37	21	promoted	promote	VERB
cusj-7408	37	22	by	by	ADP
cusj-7408	37	23	inflammatory	inflammatory	ADJ
cusj-7408	37	24	processes	process	NOUN
cusj-7408	37	25	.	.	PUNCT
cusj-7408	38	1	desynchronized	desynchronize	VERB
cusj-7408	38	2	interaction	interaction	NOUN
cusj-7408	38	3	between	between	ADP
cusj-7408	38	4	mucosal	mucosal	NOUN
cusj-7408	38	5	organs	organ	NOUN
cusj-7408	38	6	and	and	CCONJ
cusj-7408	38	7	a	a	DET
cusj-7408	38	8	complex	complex	ADJ
cusj-7408	38	9	community	community	NOUN
cusj-7408	38	10	of	of	ADP
cusj-7408	38	11	microorganisms	microorganism	NOUN
cusj-7408	38	12	colonizing	colonize	VERB
cusj-7408	38	13	them	they	PRON
cusj-7408	38	14	have	have	AUX
cusj-7408	38	15	emerged	emerge	VERB
cusj-7408	38	16	as	as	ADP
cusj-7408	38	17	a	a	DET
cusj-7408	38	18	potential	potential	ADJ
cusj-7408	38	19	source	source	NOUN
cusj-7408	38	20	of	of	ADP
cusj-7408	38	21	inflammation	inflammation	NOUN
cusj-7408	38	22	underlining	underline	VERB
cusj-7408	38	23	diseases	disease	NOUN
cusj-7408	38	24	promoted	promote	VERB
cusj-7408	38	25	by	by	ADP
cusj-7408	38	26	circadian	circadian	ADJ
cusj-7408	38	27	clock	clock	NOUN
cusj-7408	38	28	disruption	disruption	NOUN
cusj-7408	38	29	.	.	PUNCT
cusj-7408	39	1	the	the	DET
cusj-7408	39	2	source	source	NOUN
cusj-7408	39	3	of	of	ADP
cusj-7408	39	4	this	this	DET
cusj-7408	39	5	inflammation	inflammation	NOUN
cusj-7408	39	6	can	can	AUX
cusj-7408	39	7	be	be	AUX
cusj-7408	39	8	located	locate	VERB
cusj-7408	39	9	at	at	ADP
cusj-7408	39	10	the	the	DET
cusj-7408	39	11	gut	gut	NOUN
cusj-7408	39	12	epithelium	epithelium	NOUN
cusj-7408	40	1	[	[	X
cusj-7408	40	2	18	18	NUM
cusj-7408	40	3	]	]	PUNCT
cusj-7408	40	4	.	.	PUNCT
cusj-7408	41	1	the	the	DET
cusj-7408	41	2	intestinal	intestinal	ADJ
cusj-7408	41	3	epithelium	epithelium	NOUN
cusj-7408	41	4	is	be	AUX
cusj-7408	41	5	comprised	comprise	VERB
cusj-7408	41	6	of	of	ADP
cusj-7408	41	7	a	a	DET
cusj-7408	41	8	single	single	ADJ
cusj-7408	41	9	-	-	PUNCT
cusj-7408	41	10	cell	cell	NOUN
cusj-7408	41	11	layer	layer	NOUN
cusj-7408	41	12	constituting	constitute	VERB
cusj-7408	41	13	the	the	DET
cusj-7408	41	14	largest	large	ADJ
cusj-7408	41	15	and	and	CCONJ
cusj-7408	41	16	most	most	ADV
cusj-7408	41	17	important	important	ADJ
cusj-7408	41	18	barrier	barrier	NOUN
cusj-7408	41	19	against	against	ADP
cusj-7408	41	20	the	the	DET
cusj-7408	41	21	external	external	ADJ
cusj-7408	41	22	environment	environment	NOUN
cusj-7408	41	23	[	[	X
cusj-7408	41	24	19	19	NUM
cusj-7408	41	25	]	]	PUNCT
cusj-7408	41	26	.	.	PUNCT
cusj-7408	42	1	acting	act	VERB
cusj-7408	42	2	as	as	ADP
cusj-7408	42	3	a	a	DET
cusj-7408	42	4	selectively	selectively	ADV
cusj-7408	42	5	permeable	permeable	ADJ
cusj-7408	42	6	barrier	barrier	NOUN
cusj-7408	42	7	,	,	PUNCT
cusj-7408	42	8	the	the	DET
cusj-7408	42	9	intestinal	intestinal	ADJ
cusj-7408	42	10	epithelium	epithelium	NOUN
cusj-7408	42	11	can	can	AUX
cusj-7408	42	12	permit	permit	VERB
cusj-7408	42	13	the	the	DET
cusj-7408	42	14	absorption	absorption	NOUN
cusj-7408	42	15	of	of	ADP
cusj-7408	42	16	nutrients	nutrient	NOUN
cusj-7408	42	17	,	,	PUNCT
cusj-7408	42	18	electrolytes	electrolyte	NOUN
cusj-7408	42	19	and	and	CCONJ
cusj-7408	42	20	water	water	NOUN
cusj-7408	42	21	,	,	PUNCT
cusj-7408	42	22	while	while	SCONJ
cusj-7408	42	23	simultaneously	simultaneously	ADV
cusj-7408	42	24	defending	defend	VERB
cusj-7408	42	25	against	against	ADP
cusj-7408	42	26	toxins	toxin	NOUN
cusj-7408	42	27	[	[	X
cusj-7408	42	28	19	19	NUM
cusj-7408	42	29	]	]	PUNCT
cusj-7408	42	30	.	.	PUNCT
cusj-7408	43	1	the	the	DET
cusj-7408	43	2	epithelium	epithelium	NOUN
cusj-7408	43	3	maintains	maintain	VERB
cusj-7408	43	4	an	an	DET
cusj-7408	43	5	effective	effective	ADJ
cusj-7408	43	6	barrier	barrier	NOUN
cusj-7408	43	7	through	through	ADP
cusj-7408	43	8	the	the	DET
cusj-7408	43	9	help	help	NOUN
cusj-7408	43	10	of	of	ADP
cusj-7408	43	11	protein	protein	NOUN
cusj-7408	43	12	-	-	PUNCT
cusj-7408	43	13	protein	protein	NOUN
cusj-7408	43	14	networks	network	NOUN
cusj-7408	43	15	forming	form	VERB
cusj-7408	43	16	complexes	complex	NOUN
cusj-7408	43	17	like	like	ADP
cusj-7408	43	18	tight	tight	ADJ
cusj-7408	43	19	junctions	junction	NOUN
cusj-7408	43	20	[	[	X
cusj-7408	43	21	19	19	NUM
cusj-7408	43	22	]	]	PUNCT
cusj-7408	43	23	.	.	PUNCT
cusj-7408	44	1	a	a	DET
cusj-7408	44	2	compromised	compromise	VERB
cusj-7408	44	3	epithelial	epithelial	ADJ
cusj-7408	44	4	barrier	barrier	NOUN
cusj-7408	44	5	allowing	allow	VERB
cusj-7408	44	6	the	the	DET
cusj-7408	44	7	passage	passage	NOUN
cusj-7408	44	8	of	of	ADP
cusj-7408	44	9	toxins	toxin	NOUN
cusj-7408	44	10	,	,	PUNCT
cusj-7408	44	11	antigens	antigen	NOUN
cusj-7408	44	12	and	and	CCONJ
cusj-7408	44	13	bacteria	bacteria	NOUN
cusj-7408	44	14	into	into	ADP
cusj-7408	44	15	the	the	DET
cusj-7408	44	16	blood	blood	NOUN
cusj-7408	44	17	stream	stream	NOUN
cusj-7408	44	18	creates	create	VERB
cusj-7408	44	19	what	what	PRON
cusj-7408	44	20	is	be	AUX
cusj-7408	44	21	commonly	commonly	ADV
cusj-7408	44	22	known	know	VERB
cusj-7408	44	23	as	as	ADP
cusj-7408	44	24	“	"	PUNCT
cusj-7408	44	25	leaky	leaky	ADJ
cusj-7408	44	26	gut	gut	NOUN
cusj-7408	44	27	”	"	PUNCT
cusj-7408	45	1	[	[	X
cusj-7408	45	2	20	20	NUM
cusj-7408	45	3	]	]	PUNCT
cusj-7408	45	4	.	.	PUNCT
cusj-7408	46	1	there	there	PRON
cusj-7408	46	2	is	be	VERB
cusj-7408	46	3	therefore	therefore	ADV
cusj-7408	46	4	an	an	DET
cusj-7408	46	5	urgent	urgent	ADJ
cusj-7408	46	6	need	need	NOUN
cusj-7408	46	7	to	to	PART
cusj-7408	46	8	better	well	ADV
cusj-7408	46	9	identify	identify	VERB
cusj-7408	46	10	the	the	DET
cusj-7408	46	11	players	player	NOUN
cusj-7408	46	12	behind	behind	ADP
cusj-7408	46	13	the	the	DET
cusj-7408	46	14	disruption	disruption	NOUN
cusj-7408	46	15	and	and	CCONJ
cusj-7408	46	16	upkeep	upkeep	NOUN
cusj-7408	46	17	of	of	ADP
cusj-7408	46	18	intestinal	intestinal	ADJ
cusj-7408	46	19	barrier	barrier	NOUN
cusj-7408	46	20	function	function	NOUN
cusj-7408	46	21	,	,	PUNCT
cusj-7408	46	22	to	to	PART
cusj-7408	46	23	devise	devise	VERB
cusj-7408	46	24	methods	method	NOUN
cusj-7408	46	25	to	to	PART
cusj-7408	46	26	combat	combat	VERB
cusj-7408	46	27	negative	negative	ADJ
cusj-7408	46	28	barrier	barrier	NOUN
cusj-7408	46	29	alteration	alteration	NOUN
cusj-7408	46	30	.	.	PUNCT
cusj-7408	47	1	in	in	ADP
cusj-7408	47	2	this	this	DET
cusj-7408	47	3	project	project	NOUN
cusj-7408	47	4	we	we	PRON
cusj-7408	47	5	studied	study	VERB
cusj-7408	47	6	different	different	ADJ
cusj-7408	47	7	factors	factor	NOUN
cusj-7408	47	8	affecting	affect	VERB
cusj-7408	47	9	permeability	permeability	NOUN
cusj-7408	47	10	in	in	ADP
cusj-7408	47	11	the	the	DET
cusj-7408	47	12	epithelial	epithelial	ADJ
cusj-7408	47	13	barrier	barrier	NOUN
cusj-7408	47	14	,	,	PUNCT
cusj-7408	47	15	specifically	specifically	ADV
cusj-7408	47	16	in	in	ADP
cusj-7408	47	17	the	the	DET
cusj-7408	47	18	small	small	ADJ
cusj-7408	47	19	intestine	intestine	NOUN
cusj-7408	47	20	,	,	PUNCT
cusj-7408	47	21	the	the	DET
cusj-7408	47	22	part	part	NOUN
cusj-7408	47	23	of	of	ADP
cusj-7408	47	24	the	the	DET
cusj-7408	47	25	intestine	intestine	NOUN
cusj-7408	47	26	responsible	responsible	ADJ
cusj-7408	47	27	for	for	ADP
cusj-7408	47	28	the	the	DET
cusj-7408	47	29	majority	majority	NOUN
cusj-7408	47	30	of	of	ADP
cusj-7408	47	31	nutrient	nutrient	ADJ
cusj-7408	47	32	absorption	absorption	NOUN
cusj-7408	47	33	[	[	X
cusj-7408	47	34	21	21	NUM
cusj-7408	47	35	]	]	PUNCT
cusj-7408	47	36	.	.	PUNCT
cusj-7408	48	1	recent	recent	ADJ
cusj-7408	48	2	studies	study	NOUN
cusj-7408	48	3	on	on	ADP
cusj-7408	48	4	type	type	NOUN
cusj-7408	48	5	2	2	NUM
cusj-7408	48	6	diabetes	diabetes	NOUN
cusj-7408	48	7	and	and	CCONJ
cusj-7408	48	8	obesity	obesity	NOUN
cusj-7408	48	9	have	have	AUX
cusj-7408	48	10	elucidated	elucidate	VERB
cusj-7408	48	11	the	the	DET
cusj-7408	48	12	link	link	NOUN
cusj-7408	48	13	between	between	ADP
cusj-7408	48	14	microbiome	microbiome	NOUN
cusj-7408	48	15	composition	composition	NOUN
cusj-7408	48	16	and	and	CCONJ
cusj-7408	48	17	small	small	ADJ
cusj-7408	48	18	intestine	intestine	NOUN
cusj-7408	48	19	permeability	permeability	NOUN
cusj-7408	48	20	;	;	PUNCT
cusj-7408	48	21	however	however	ADV
cusj-7408	48	22	,	,	PUNCT
cusj-7408	48	23	the	the	DET
cusj-7408	48	24	mediators	mediator	NOUN
cusj-7408	48	25	of	of	ADP
cusj-7408	48	26	these	these	DET
cusj-7408	48	27	effects	effect	NOUN
cusj-7408	48	28	have	have	VERB
cusj-7408	48	29	yet	yet	ADV
cusj-7408	48	30	to	to	PART
cusj-7408	48	31	be	be	AUX
cusj-7408	48	32	determined	determine	VERB
cusj-7408	48	33	[	[	PUNCT
cusj-7408	48	34	22	22	NUM
cusj-7408	48	35	]	]	PUNCT
cusj-7408	48	36	.	.	PUNCT
cusj-7408	49	1	over	over	ADP
cusj-7408	49	2	the	the	DET
cusj-7408	49	3	course	course	NOUN
cusj-7408	49	4	of	of	ADP
cusj-7408	49	5	this	this	DET
cusj-7408	49	6	project	project	NOUN
cusj-7408	49	7	,	,	PUNCT
cusj-7408	49	8	we	we	PRON
cusj-7408	49	9	demonstrated	demonstrate	VERB
cusj-7408	49	10	the	the	DET
cusj-7408	49	11	consequences	consequence	NOUN
cusj-7408	49	12	that	that	PRON
cusj-7408	49	13	genetic	genetic	ADJ
cusj-7408	49	14	and	and	CCONJ
cusj-7408	49	15	environmental	environmental	ADJ
cusj-7408	49	16	circadian	circadian	ADJ
cusj-7408	49	17	disruption	disruption	NOUN
cusj-7408	49	18	have	have	VERB
cusj-7408	49	19	on	on	ADP
cusj-7408	49	20	gut	gut	NOUN
cusj-7408	49	21	barrier	barrier	NOUN
cusj-7408	49	22	integrity	integrity	NOUN
cusj-7408	49	23	in	in	ADP
cusj-7408	49	24	mice	mouse	NOUN
cusj-7408	49	25	.	.	PUNCT
cusj-7408	50	1	furthermore	furthermore	ADV
cusj-7408	50	2	,	,	PUNCT
cusj-7408	50	3	we	we	PRON
cusj-7408	50	4	8	8	NUM
cusj-7408	50	5	columbia	columbia	PROPN
cusj-7408	50	6	undergraduate	undergraduate	PROPN
cusj-7408	50	7	science	science	PROPN
cusj-7408	50	8	journal	journal	PROPN
cusj-7408	50	9	vol	vol	NOUN
cusj-7408	50	10	.	.	PROPN
cusj-7408	50	11	15	15	NUM
cusj-7408	50	12	,	,	PUNCT
cusj-7408	50	13	2021	2021	NUM
cusj-7408	50	14	pinker	pinker	PROPN
cusj-7408	50	15	et	et	PROPN
cusj-7408	50	16	.	.	PUNCT
cusj-7408	51	1	al	al	PROPN
cusj-7408	51	2	.	.	PROPN
cusj-7408	51	3	found	find	VERB
cusj-7408	51	4	evidence	evidence	NOUN
cusj-7408	51	5	to	to	PART
cusj-7408	51	6	suggest	suggest	VERB
cusj-7408	51	7	that	that	SCONJ
cusj-7408	51	8	altering	alter	VERB
cusj-7408	51	9	the	the	DET
cusj-7408	51	10	microbiome	microbiome	NOUN
cusj-7408	51	11	,	,	PUNCT
cusj-7408	51	12	either	either	CCONJ
cusj-7408	51	13	with	with	ADP
cusj-7408	51	14	diet	diet	NOUN
cusj-7408	51	15	intervention	intervention	NOUN
cusj-7408	51	16	or	or	CCONJ
cusj-7408	51	17	antibiotic	antibiotic	ADJ
cusj-7408	51	18	treatment	treatment	NOUN
cusj-7408	51	19	,	,	PUNCT
cusj-7408	51	20	can	can	AUX
cusj-7408	51	21	disrupt	disrupt	VERB
cusj-7408	51	22	the	the	DET
cusj-7408	51	23	diurnal	diurnal	ADJ
cusj-7408	51	24	oscillations	oscillation	NOUN
cusj-7408	51	25	and	and	CCONJ
cusj-7408	51	26	alter	alter	VERB
cusj-7408	51	27	permeability	permeability	NOUN
cusj-7408	51	28	.	.	PUNCT
cusj-7408	52	1	understanding	understand	VERB
cusj-7408	52	2	the	the	DET
cusj-7408	52	3	key	key	ADJ
cusj-7408	52	4	players	player	NOUN
cusj-7408	52	5	behind	behind	ADP
cusj-7408	52	6	circadian	circadian	ADJ
cusj-7408	52	7	disruption	disruption	NOUN
cusj-7408	52	8	and	and	CCONJ
cusj-7408	52	9	intestinal	intestinal	ADJ
cusj-7408	52	10	barrier	barrier	NOUN
cusj-7408	52	11	maintenance	maintenance	NOUN
cusj-7408	52	12	has	have	VERB
cusj-7408	52	13	potential	potential	NOUN
cusj-7408	52	14	in	in	ADP
cusj-7408	52	15	therapeutic	therapeutic	ADJ
cusj-7408	52	16	and	and	CCONJ
cusj-7408	52	17	preventative	preventative	ADJ
cusj-7408	52	18	medicine	medicine	NOUN
cusj-7408	52	19	interventions	intervention	NOUN
cusj-7408	52	20	.	.	PUNCT
cusj-7408	53	1	methods	method	NOUN
cusj-7408	53	2	mice	mouse	NOUN
cusj-7408	53	3	under	under	ADP
cusj-7408	53	4	normal	normal	ADJ
cusj-7408	53	5	conditions	condition	NOUN
cusj-7408	53	6	,	,	PUNCT
cusj-7408	53	7	mice	mouse	NOUN
cusj-7408	53	8	had	have	VERB
cusj-7408	53	9	strict	strict	ADJ
cusj-7408	53	10	lightdark	lightdark	ADJ
cusj-7408	53	11	cycles	cycle	NOUN
cusj-7408	53	12	lasting	last	VERB
cusj-7408	53	13	12	12	NUM
cusj-7408	53	14	hours	hour	NOUN
cusj-7408	53	15	each	each	PRON
cusj-7408	53	16	.	.	PUNCT
cusj-7408	54	1	lights	light	NOUN
cusj-7408	54	2	were	be	AUX
cusj-7408	54	3	turned	turn	VERB
cusj-7408	54	4	on	on	ADP
cusj-7408	54	5	either	either	CCONJ
cusj-7408	54	6	at	at	ADP
cusj-7408	54	7	11:30	11:30	NUM
cusj-7408	54	8	am	am	NOUN
cusj-7408	54	9	or	or	CCONJ
cusj-7408	54	10	11:30	11:30	NUM
cusj-7408	54	11	pm	pm	NOUN
cusj-7408	54	12	,	,	PUNCT
cusj-7408	54	13	zt0	zt0	NOUN
cusj-7408	54	14	or	or	CCONJ
cusj-7408	54	15	zt12	zt12	PROPN
cusj-7408	54	16	respectively	respectively	ADV
cusj-7408	54	17	.	.	PUNCT
cusj-7408	55	1	for	for	ADP
cusj-7408	55	2	the	the	DET
cusj-7408	55	3	induction	induction	NOUN
cusj-7408	55	4	of	of	ADP
cusj-7408	55	5	jet	jet	NOUN
cusj-7408	55	6	lag	lag	NOUN
cusj-7408	55	7	,	,	PUNCT
cusj-7408	55	8	mice	mouse	NOUN
cusj-7408	55	9	were	be	AUX
cusj-7408	55	10	shifted	shift	VERB
cusj-7408	55	11	between	between	ADP
cusj-7408	55	12	both	both	PRON
cusj-7408	55	13	control	control	VERB
cusj-7408	55	14	light	light	ADJ
cusj-7408	55	15	conditions	condition	NOUN
cusj-7408	55	16	every	every	DET
cusj-7408	55	17	3	3	NUM
cusj-7408	55	18	days	day	NOUN
cusj-7408	55	19	for	for	ADP
cusj-7408	55	20	3	3	NUM
cusj-7408	55	21	weeks	week	NOUN
cusj-7408	55	22	at	at	ADP
cusj-7408	55	23	a	a	DET
cusj-7408	55	24	consistent	consistent	ADJ
cusj-7408	55	25	but	but	CCONJ
cusj-7408	55	26	arbitrary	arbitrary	ADJ
cusj-7408	55	27	time	time	NOUN
cusj-7408	55	28	.	.	PUNCT
cusj-7408	56	1	jet	jet	NOUN
cusj-7408	56	2	lag	lag	NOUN
cusj-7408	56	3	mice	mouse	NOUN
cusj-7408	56	4	were	be	AUX
cusj-7408	56	5	moved	move	VERB
cusj-7408	56	6	between	between	ADP
cusj-7408	56	7	the	the	DET
cusj-7408	56	8	different	different	ADJ
cusj-7408	56	9	light	light	NOUN
cusj-7408	56	10	schedules	schedule	NOUN
cusj-7408	56	11	every	every	DET
cusj-7408	56	12	3	3	NUM
cusj-7408	56	13	days	day	NOUN
cusj-7408	56	14	for	for	ADP
cusj-7408	56	15	3	3	NUM
cusj-7408	56	16	weeks	week	NOUN
cusj-7408	56	17	.	.	PUNCT
cusj-7408	57	1	for	for	ADP
cusj-7408	57	2	consistency	consistency	NOUN
cusj-7408	57	3	,	,	PUNCT
cusj-7408	57	4	jet	jet	NOUN
cusj-7408	57	5	lag	lag	NOUN
cusj-7408	57	6	mice	mouse	NOUN
cusj-7408	57	7	were	be	AUX
cusj-7408	57	8	only	only	ADV
cusj-7408	57	9	experimented	experiment	VERB
cusj-7408	57	10	on	on	ADP
cusj-7408	57	11	at	at	ADP
cusj-7408	57	12	1:30	1:30	NUM
cusj-7408	57	13	pm	pm	NOUN
cusj-7408	57	14	,	,	PUNCT
cusj-7408	57	15	which	which	PRON
cusj-7408	57	16	was	be	AUX
cusj-7408	57	17	synchronized	synchronize	VERB
cusj-7408	57	18	with	with	ADP
cusj-7408	57	19	the	the	DET
cusj-7408	57	20	zts	zts	NOUN
cusj-7408	57	21	of	of	ADP
cusj-7408	57	22	the	the	DET
cusj-7408	57	23	control	control	NOUN
cusj-7408	57	24	group	group	NOUN
cusj-7408	57	25	(	(	PUNCT
cusj-7408	57	26	i.e.	i.e.	X
cusj-7408	57	27	,	,	PUNCT
cusj-7408	57	28	zt14	zt14	PROPN
cusj-7408	57	29	of	of	ADP
cusj-7408	57	30	jet	jet	NOUN
cusj-7408	57	31	lag	lag	NOUN
cusj-7408	57	32	mice	mouse	NOUN
cusj-7408	57	33	corresponded	correspond	VERB
cusj-7408	57	34	to	to	ADP
cusj-7408	57	35	zt14	zt14	PROPN
cusj-7408	57	36	of	of	ADP
cusj-7408	57	37	control	control	NOUN
cusj-7408	57	38	mice	mouse	NOUN
cusj-7408	57	39	,	,	PUNCT
cusj-7408	57	40	as	as	SCONJ
cusj-7408	57	41	all	all	DET
cusj-7408	57	42	mice	mouse	NOUN
cusj-7408	57	43	were	be	AUX
cusj-7408	57	44	exposed	expose	VERB
cusj-7408	57	45	to	to	ADP
cusj-7408	57	46	the	the	DET
cusj-7408	57	47	same	same	ADJ
cusj-7408	57	48	light	light	ADJ
cusj-7408	57	49	-	-	PUNCT
cusj-7408	57	50	dark	dark	NOUN
cusj-7408	57	51	conditions	condition	NOUN
cusj-7408	57	52	at	at	ADP
cusj-7408	57	53	the	the	DET
cusj-7408	57	54	onset	onset	NOUN
cusj-7408	57	55	of	of	ADP
cusj-7408	57	56	sample	sample	NOUN
cusj-7408	57	57	collection	collection	NOUN
cusj-7408	57	58	)	)	PUNCT
cusj-7408	57	59	.	.	PUNCT
cusj-7408	58	1	hfd	hfd	PROPN
cusj-7408	58	2	mice	mouse	NOUN
cusj-7408	58	3	were	be	AUX
cusj-7408	58	4	placed	place	VERB
cusj-7408	58	5	in	in	ADP
cusj-7408	58	6	zt2	zt2	PROPN
cusj-7408	58	7	and	and	CCONJ
cusj-7408	58	8	zt14	zt14	PROPN
cusj-7408	58	9	light	light	ADJ
cusj-7408	58	10	-	-	PUNCT
cusj-7408	58	11	dark	dark	NOUN
cusj-7408	58	12	cycles	cycle	NOUN
cusj-7408	58	13	to	to	PART
cusj-7408	58	14	measure	measure	VERB
cusj-7408	58	15	two	two	NUM
cusj-7408	58	16	time	time	NOUN
cusj-7408	58	17	points	point	NOUN
cusj-7408	58	18	upon	upon	SCONJ
cusj-7408	58	19	sacrifice	sacrifice	NOUN
cusj-7408	58	20	.	.	PUNCT
cusj-7408	59	1	these	these	DET
cusj-7408	59	2	mice	mouse	NOUN
cusj-7408	59	3	were	be	AUX
cusj-7408	59	4	fed	feed	VERB
cusj-7408	59	5	a	a	DET
cusj-7408	59	6	strict	strict	ADJ
cusj-7408	59	7	hfd	hfd	NOUN
cusj-7408	59	8	for	for	ADP
cusj-7408	59	9	3	3	NUM
cusj-7408	59	10	weeks	week	NOUN
cusj-7408	59	11	.	.	PUNCT
cusj-7408	60	1	mice	mouse	NOUN
cusj-7408	60	2	receiving	receive	VERB
cusj-7408	60	3	antibiotic	antibiotic	ADJ
cusj-7408	60	4	treatment	treatment	NOUN
cusj-7408	60	5	,	,	PUNCT
cusj-7408	60	6	either	either	CCONJ
cusj-7408	60	7	received	receive	VERB
cusj-7408	60	8	exclusively	exclusively	ADV
cusj-7408	60	9	vancomycin	vancomycin	PROPN
cusj-7408	60	10	(	(	PUNCT
cusj-7408	60	11	1	1	NUM
cusj-7408	60	12	g	g	NOUN
cusj-7408	60	13	/	/	SYM
cusj-7408	60	14	l	l	NOUN
cusj-7408	60	15	)	)	PUNCT
cusj-7408	60	16	,	,	PUNCT
cusj-7408	60	17	ampicillin	ampicillin	NOUN
cusj-7408	60	18	(	(	PUNCT
cusj-7408	60	19	1	1	NUM
cusj-7408	60	20	g	g	NOUN
cusj-7408	60	21	/	/	SYM
cusj-7408	60	22	l	l	NOUN
cusj-7408	60	23	)	)	PUNCT
cusj-7408	60	24	,	,	PUNCT
cusj-7408	60	25	neomycin	neomycin	PROPN
cusj-7408	60	26	(	(	PUNCT
cusj-7408	60	27	1	1	NUM
cusj-7408	60	28	g	g	NOUN
cusj-7408	60	29	/	/	SYM
cusj-7408	60	30	l	l	NOUN
cusj-7408	60	31	)	)	PUNCT
cusj-7408	60	32	,	,	PUNCT
cusj-7408	60	33	and	and	CCONJ
cusj-7408	60	34	metronidazole	metronidazole	NOUN
cusj-7408	60	35	(	(	PUNCT
cusj-7408	60	36	1	1	NUM
cusj-7408	60	37	g	g	NOUN
cusj-7408	60	38	/	/	SYM
cusj-7408	60	39	l	l	NOUN
cusj-7408	60	40	)	)	PUNCT
cusj-7408	60	41	or	or	CCONJ
cusj-7408	60	42	a	a	DET
cusj-7408	60	43	combination	combination	NOUN
cusj-7408	60	44	of	of	ADP
cusj-7408	60	45	all	all	DET
cusj-7408	60	46	four	four	NUM
cusj-7408	60	47	in	in	ADP
cusj-7408	60	48	drinking	drinking	NOUN
cusj-7408	60	49	water	water	NOUN
cusj-7408	60	50	for	for	ADP
cusj-7408	60	51	3	3	NUM
cusj-7408	60	52	weeks	week	NOUN
cusj-7408	60	53	.	.	PUNCT
cusj-7408	61	1	per	per	ADP
cusj-7408	61	2	1/2/(ko	1/2/(ko	NUM
cusj-7408	61	3	)	)	PUNCT
cusj-7408	61	4	and	and	CCONJ
cusj-7408	61	5	per1/2-/+	per1/2-/+	PROPN
cusj-7408	61	6	(	(	PUNCT
cusj-7408	61	7	wt	wt	NOUN
cusj-7408	61	8	)	)	PUNCT
cusj-7408	61	9	were	be	AUX
cusj-7408	61	10	housed	house	VERB
cusj-7408	61	11	under	under	ADP
cusj-7408	61	12	normal	normal	ADJ
cusj-7408	61	13	conditions	condition	NOUN
cusj-7408	61	14	and	and	CCONJ
cusj-7408	61	15	sacrificed	sacrifice	VERB
cusj-7408	61	16	at	at	ADP
cusj-7408	61	17	zt	zt	PROPN
cusj-7408	61	18	14	14	NUM
cusj-7408	61	19	.	.	PUNCT
cusj-7408	62	1	fecal	fecal	ADJ
cusj-7408	62	2	microbiome	microbiome	NOUN
cusj-7408	62	3	transplantation	transplantation	NOUN
cusj-7408	62	4	(	(	PUNCT
cusj-7408	62	5	fmt	fmt	NOUN
cusj-7408	62	6	)	)	PUNCT
cusj-7408	62	7	microbiome	microbiome	NOUN
cusj-7408	62	8	samples	sample	NOUN
cusj-7408	62	9	were	be	AUX
cusj-7408	62	10	collected	collect	VERB
cusj-7408	62	11	and	and	CCONJ
cusj-7408	62	12	stored	store	VERB
cusj-7408	62	13	in	in	ADP
cusj-7408	62	14	eppendorf	eppendorf	PROPN
cusj-7408	62	15	tubes	tube	NOUN
cusj-7408	62	16	containing	contain	VERB
cusj-7408	62	17	20	20	NUM
cusj-7408	62	18	%	%	NOUN
cusj-7408	62	19	glycerol	glycerol	NOUN
cusj-7408	62	20	.	.	PUNCT
cusj-7408	63	1	fecal	fecal	ADJ
cusj-7408	63	2	samples	sample	NOUN
cusj-7408	63	3	were	be	AUX
cusj-7408	63	4	homogenized	homogenize	VERB
cusj-7408	63	5	and	and	CCONJ
cusj-7408	63	6	stored	store	VERB
cusj-7408	63	7	in	in	ADP
cusj-7408	63	8	dry	dry	ADJ
cusj-7408	63	9	ice	ice	NOUN
cusj-7408	63	10	before	before	ADP
cusj-7408	63	11	long	long	ADJ
cusj-7408	63	12	-	-	PUNCT
cusj-7408	63	13	term	term	NOUN
cusj-7408	63	14	storage	storage	NOUN
cusj-7408	63	15	at	at	ADP
cusj-7408	63	16	-80	-80	NOUN
cusj-7408	63	17	°	°	PRON
cusj-7408	63	18	c.	c.	NOUN
cusj-7408	63	19	for	for	ADP
cusj-7408	63	20	the	the	DET
cusj-7408	63	21	microbiome	microbiome	NOUN
cusj-7408	63	22	transplantation	transplantation	NOUN
cusj-7408	63	23	,	,	PUNCT
cusj-7408	63	24	0.1	0.1	NUM
cusj-7408	63	25	g	g	NOUN
cusj-7408	63	26	of	of	ADP
cusj-7408	63	27	thawed	thaw	VERB
cusj-7408	63	28	fecal	fecal	ADJ
cusj-7408	63	29	sample	sample	NOUN
cusj-7408	63	30	was	be	AUX
cusj-7408	63	31	mixed	mix	VERB
cusj-7408	63	32	in	in	ADP
cusj-7408	63	33	1ml	1ml	ADJ
cusj-7408	63	34	sterile	sterile	ADJ
cusj-7408	63	35	pbs	pbs	NOUN
cusj-7408	63	36	and	and	CCONJ
cusj-7408	63	37	200	200	NUM
cusj-7408	63	38	μl	μl	ADP
cusj-7408	63	39	of	of	ADP
cusj-7408	63	40	the	the	DET
cusj-7408	63	41	diluted	diluted	ADJ
cusj-7408	63	42	sample	sample	NOUN
cusj-7408	63	43	was	be	AUX
cusj-7408	63	44	gavaged	gavage	VERB
cusj-7408	63	45	per	per	ADP
cusj-7408	63	46	mouse	mouse	NOUN
cusj-7408	63	47	.	.	PUNCT
cusj-7408	64	1	hfd	hfd	PROPN
cusj-7408	64	2	microbiome	microbiome	PROPN
cusj-7408	64	3	samples	sample	NOUN
cusj-7408	64	4	were	be	AUX
cusj-7408	64	5	taken	take	VERB
cusj-7408	64	6	from	from	ADP
cusj-7408	64	7	mice	mouse	NOUN
cusj-7408	64	8	fed	fed	PROPN
cusj-7408	64	9	ad	ad	PROPN
cusj-7408	64	10	libitum	libitum	PROPN
cusj-7408	64	11	hfd	hfd	PROPN
cusj-7408	64	12	for	for	ADP
cusj-7408	64	13	4	4	NUM
cusj-7408	64	14	weeks	week	NOUN
cusj-7408	64	15	.	.	PUNCT
cusj-7408	65	1	measuring	measure	VERB
cusj-7408	65	2	permeability	permeability	NOUN
cusj-7408	65	3	with	with	ADP
cusj-7408	65	4	fitc	fitc	NOUN
cusj-7408	65	5	-	-	PUNCT
cusj-7408	65	6	dextran	dextran	VERB
cusj-7408	65	7	food	food	NOUN
cusj-7408	65	8	was	be	AUX
cusj-7408	65	9	removed	remove	VERB
cusj-7408	65	10	from	from	ADP
cusj-7408	65	11	mice	mouse	NOUN
cusj-7408	65	12	2	2	NUM
cusj-7408	65	13	hours	hour	NOUN
cusj-7408	65	14	before	before	ADP
cusj-7408	65	15	gavage	gavage	NOUN
cusj-7408	65	16	(	(	PUNCT
cusj-7408	65	17	starting	start	VERB
cusj-7408	65	18	at	at	ADP
cusj-7408	65	19	9	9	NUM
cusj-7408	65	20	am	am	NOUN
cusj-7408	65	21	)	)	PUNCT
cusj-7408	65	22	.	.	PUNCT
cusj-7408	66	1	the	the	DET
cusj-7408	66	2	solution	solution	NOUN
cusj-7408	66	3	was	be	AUX
cusj-7408	66	4	made	make	VERB
cusj-7408	66	5	with	with	ADP
cusj-7408	66	6	4kda	4kda	PROPN
cusj-7408	66	7	fluorescein	fluorescein	NOUN
cusj-7408	66	8	isothiocyanate	isothiocyanate	NOUN
cusj-7408	66	9	(	(	PUNCT
cusj-7408	66	10	fitc)-dextran	fitc)-dextran	NOUN
cusj-7408	66	11	dissolved	dissolve	VERB
cusj-7408	66	12	in	in	ADP
cusj-7408	66	13	a	a	DET
cusj-7408	66	14	phosphate	phosphate	ADJ
cusj-7408	66	15	buffered	buffer	VERB
cusj-7408	66	16	saline	saline	NOUN
cusj-7408	66	17	(	(	PUNCT
cusj-7408	66	18	pbs	pbs	PROPN
cusj-7408	66	19	)	)	PUNCT
cusj-7408	66	20	with	with	ADP
cusj-7408	66	21	a	a	DET
cusj-7408	66	22	concentration	concentration	NOUN
cusj-7408	66	23	of	of	ADP
cusj-7408	66	24	40	40	NUM
cusj-7408	66	25	mg	mg	NUM
cusj-7408	66	26	/	/	SYM
cusj-7408	66	27	ml	ml	NOUN
cusj-7408	66	28	.	.	PUNCT
cusj-7408	67	1	at	at	ADP
cusj-7408	67	2	11	11	NUM
cusj-7408	67	3	am	am	NOUN
cusj-7408	67	4	,	,	PUNCT
cusj-7408	67	5	mice	mouse	NOUN
cusj-7408	67	6	were	be	AUX
cusj-7408	67	7	gavaged	gavage	VERB
cusj-7408	67	8	with	with	ADP
cusj-7408	67	9	200	200	NUM
cusj-7408	67	10	μl	μl	ADP
cusj-7408	67	11	dextran	dextran	NOUN
cusj-7408	67	12	.	.	PUNCT
cusj-7408	68	1	after	after	ADP
cusj-7408	68	2	2.5	2.5	NUM
cusj-7408	68	3	hours	hour	NOUN
cusj-7408	68	4	(	(	PUNCT
cusj-7408	68	5	1:30	1:30	NUM
cusj-7408	68	6	pm	pm	NOUN
cusj-7408	68	7	,	,	PUNCT
cusj-7408	68	8	zt14	zt14	PROPN
cusj-7408	68	9	)	)	PUNCT
cusj-7408	68	10	,	,	PUNCT
cusj-7408	68	11	blood	blood	NOUN
cusj-7408	68	12	was	be	AUX
cusj-7408	68	13	drawn	draw	VERB
cusj-7408	68	14	and	and	CCONJ
cusj-7408	68	15	centrifuged	centrifuge	VERB
cusj-7408	68	16	to	to	PART
cusj-7408	68	17	recover	recover	VERB
cusj-7408	68	18	the	the	DET
cusj-7408	68	19	serum	serum	NOUN
cusj-7408	68	20	.	.	PUNCT
cusj-7408	69	1	the	the	DET
cusj-7408	69	2	fluorescence	fluorescence	NOUN
cusj-7408	69	3	of	of	ADP
cusj-7408	69	4	the	the	DET
cusj-7408	69	5	serum	serum	NOUN
cusj-7408	69	6	was	be	AUX
cusj-7408	69	7	quantified	quantify	VERB
cusj-7408	69	8	at	at	ADP
cusj-7408	69	9	an	an	DET
cusj-7408	69	10	excitation	excitation	NOUN
cusj-7408	69	11	wavelength	wavelength	NOUN
cusj-7408	69	12	of	of	ADP
cusj-7408	69	13	485	485	NUM
cusj-7408	69	14	nm	nm	ADJ
cusj-7408	69	15	and	and	CCONJ
cusj-7408	69	16	emission	emission	NOUN
cusj-7408	69	17	wavelength	wavelength	NOUN
cusj-7408	69	18	of	of	ADP
cusj-7408	69	19	533	533	NUM
cusj-7408	69	20	nm	nm	NOUN
cusj-7408	69	21	using	use	VERB
cusj-7408	69	22	a	a	DET
cusj-7408	69	23	microplate	microplate	NOUN
cusj-7408	69	24	reader	reader	NOUN
cusj-7408	69	25	.	.	PUNCT
cusj-7408	70	1	ussing	usse	VERB
cusj-7408	70	2	chamber	chamber	NOUN
cusj-7408	70	3	the	the	DET
cusj-7408	70	4	ussing	usse	VERB
cusj-7408	70	5	chamber	chamber	NOUN
cusj-7408	70	6	is	be	AUX
cusj-7408	70	7	an	an	DET
cusj-7408	70	8	instrument	instrument	NOUN
cusj-7408	70	9	used	use	VERB
cusj-7408	70	10	to	to	PART
cusj-7408	70	11	measure	measure	VERB
cusj-7408	70	12	epithelial	epithelial	ADJ
cusj-7408	70	13	resistance	resistance	NOUN
cusj-7408	70	14	which	which	PRON
cusj-7408	70	15	is	be	AUX
cusj-7408	70	16	a	a	DET
cusj-7408	70	17	measure	measure	NOUN
cusj-7408	70	18	of	of	ADP
cusj-7408	70	19	epithelial	epithelial	ADJ
cusj-7408	70	20	barrier	barrier	NOUN
cusj-7408	70	21	permeability	permeability	NOUN
cusj-7408	70	22	.	.	PUNCT
cusj-7408	71	1	the	the	DET
cusj-7408	71	2	procedure	procedure	NOUN
cusj-7408	71	3	followed	follow	VERB
cusj-7408	71	4	was	be	AUX
cusj-7408	71	5	in	in	ADP
cusj-7408	71	6	accordance	accordance	NOUN
cusj-7408	71	7	with	with	ADP
cusj-7408	71	8	the	the	DET
cusj-7408	71	9	manufacturer	manufacturer	NOUN
cusj-7408	71	10	’s	’s	PART
cusj-7408	71	11	instructions	instruction	NOUN
cusj-7408	71	12	(	(	PUNCT
cusj-7408	71	13	warner	warner	PROPN
cusj-7408	71	14	instruments	instrument	NOUN
cusj-7408	71	15	,	,	PUNCT
cusj-7408	71	16	p2300	p2300	NOUN
cusj-7408	71	17	)	)	PUNCT
cusj-7408	71	18	.	.	PUNCT
cusj-7408	72	1	small	small	ADJ
cusj-7408	72	2	intestine	intestine	NOUN
cusj-7408	72	3	tissue	tissue	NOUN
cusj-7408	72	4	is	be	AUX
cusj-7408	72	5	excised	excise	VERB
cusj-7408	72	6	and	and	CCONJ
cusj-7408	72	7	immediately	immediately	ADV
cusj-7408	72	8	mounted	mount	VERB
cusj-7408	72	9	in	in	ADP
cusj-7408	72	10	the	the	DET
cusj-7408	72	11	chamber	chamber	NOUN
cusj-7408	72	12	.	.	PUNCT
cusj-7408	73	1	current	current	ADJ
cusj-7408	73	2	is	be	AUX
cusj-7408	73	3	then	then	ADV
cusj-7408	73	4	applied	apply	VERB
cusj-7408	73	5	to	to	ADP
cusj-7408	73	6	the	the	DET
cusj-7408	73	7	system	system	NOUN
cusj-7408	73	8	and	and	CCONJ
cusj-7408	73	9	voltage	voltage	NOUN
cusj-7408	73	10	clamp	clamp	NOUN
cusj-7408	73	11	recordings	recording	NOUN
cusj-7408	73	12	were	be	AUX
cusj-7408	73	13	taken	take	VERB
cusj-7408	73	14	.	.	PUNCT
cusj-7408	74	1	small	small	ADJ
cusj-7408	74	2	intestine	intestine	NOUN
cusj-7408	74	3	was	be	AUX
cusj-7408	74	4	carefully	carefully	ADV
cusj-7408	74	5	cleaned	clean	VERB
cusj-7408	74	6	and	and	CCONJ
cusj-7408	74	7	handled	handle	VERB
cusj-7408	74	8	minimally	minimally	ADV
cusj-7408	74	9	to	to	PART
cusj-7408	74	10	prevent	prevent	VERB
cusj-7408	74	11	microfracturing	microfracture	VERB
cusj-7408	74	12	the	the	DET
cusj-7408	74	13	tissue	tissue	NOUN
cusj-7408	74	14	and	and	CCONJ
cusj-7408	74	15	compromising	compromise	VERB
cusj-7408	74	16	the	the	DET
cusj-7408	74	17	results	result	NOUN
cusj-7408	74	18	.	.	PUNCT
cusj-7408	75	1	additionally	additionally	ADV
cusj-7408	75	2	,	,	PUNCT
cusj-7408	75	3	samples	sample	NOUN
cusj-7408	75	4	were	be	AUX
cusj-7408	75	5	mounted	mount	VERB
cusj-7408	75	6	within	within	ADP
cusj-7408	75	7	three	three	NUM
cusj-7408	75	8	hours	hour	NOUN
cusj-7408	75	9	of	of	ADP
cusj-7408	75	10	tissue	tissue	NOUN
cusj-7408	75	11	excise	excise	NOUN
cusj-7408	75	12	to	to	PART
cusj-7408	75	13	limit	limit	VERB
cusj-7408	75	14	cell	cell	NOUN
cusj-7408	75	15	death	death	NOUN
cusj-7408	75	16	.	.	PUNCT
cusj-7408	76	1	prr	prr	PROPN
cusj-7408	76	2	stimulation	stimulation	NOUN
cusj-7408	76	3	measures	measure	NOUN
cusj-7408	76	4	degree	degree	NOUN
cusj-7408	76	5	of	of	ADP
cusj-7408	76	6	microbial	microbial	ADJ
cusj-7408	76	7	presence	presence	NOUN
cusj-7408	76	8	at	at	ADP
cusj-7408	76	9	systemic	systemic	ADJ
cusj-7408	76	10	sites	site	NOUN
cusj-7408	76	11	prr	prr	PROPN
cusj-7408	76	12	reporter	reporter	NOUN
cusj-7408	76	13	cell	cell	NOUN
cusj-7408	76	14	lines	line	NOUN
cusj-7408	76	15	were	be	AUX
cusj-7408	76	16	obtained	obtain	VERB
cusj-7408	76	17	from	from	ADP
cusj-7408	76	18	invivogen	invivogen	PROPN
cusj-7408	76	19	(	(	PUNCT
cusj-7408	76	20	hek	hek	NOUN
cusj-7408	76	21	-	-	PUNCT
cusj-7408	76	22	blue	blue	ADJ
cusj-7408	76	23	tlr	tlr	PROPN
cusj-7408	76	24	(	(	PUNCT
cusj-7408	76	25	toll	toll	NOUN
cusj-7408	76	26	-	-	PUNCT
cusj-7408	76	27	like	like	ADJ
cusj-7408	76	28	receptors	receptor	NOUN
cusj-7408	76	29	)	)	PUNCT
cusj-7408	76	30	and	and	CCONJ
cusj-7408	76	31	nlr	nlr	PROPN
cusj-7408	76	32	(	(	PUNCT
cusj-7408	76	33	nod	nod	PROPN
cusj-7408	76	34	-	-	PUNCT
cusj-7408	76	35	like	like	ADJ
cusj-7408	76	36	receptors	receptor	NOUN
cusj-7408	76	37	)	)	PUNCT
cusj-7408	76	38	reported	report	VERB
cusj-7408	76	39	cell	cell	NOUN
cusj-7408	76	40	lines	line	NOUN
cusj-7408	76	41	):	):	PUNCT
cusj-7408	76	42	tlr2	tlr2	PROPN
cusj-7408	76	43	,	,	PUNCT
cusj-7408	76	44	tlr3	tlr3	PROPN
cusj-7408	76	45	,	,	PUNCT
cusj-7408	76	46	tlr4	tlr4	PROPN
cusj-7408	76	47	,	,	PUNCT
cusj-7408	76	48	tlr5	tlr5	PROPN
cusj-7408	76	49	,	,	PUNCT
cusj-7408	76	50	tlr7	tlr7	PROPN
cusj-7408	76	51	,	,	PUNCT
cusj-7408	76	52	tlr9	tlr9	PROPN
cusj-7408	76	53	,	,	PUNCT
cusj-7408	76	54	nod1	nod1	PROPN
cusj-7408	76	55	,	,	PUNCT
cusj-7408	76	56	nod2	nod2	NOUN
cusj-7408	76	57	.	.	PUNCT
cusj-7408	77	1	extracts	extract	NOUN
cusj-7408	77	2	from	from	ADP
cusj-7408	77	3	spleen	spleen	NOUN
cusj-7408	77	4	,	,	PUNCT
cusj-7408	77	5	liver	liver	NOUN
cusj-7408	77	6	,	,	PUNCT
cusj-7408	77	7	and	and	CCONJ
cusj-7408	77	8	serum	serum	NOUN
cusj-7408	77	9	were	be	AUX
cusj-7408	77	10	homogenized	homogenize	VERB
cusj-7408	77	11	and	and	CCONJ
cusj-7408	77	12	added	add	VERB
cusj-7408	77	13	to	to	ADP
cusj-7408	77	14	reporter	reporter	NOUN
cusj-7408	77	15	cell	cell	NOUN
cusj-7408	77	16	lines	line	NOUN
cusj-7408	77	17	incubated	incubate	VERB
cusj-7408	77	18	with	with	ADP
cusj-7408	77	19	kel	kel	NOUN
cusj-7408	77	20	-	-	PUNCT
cusj-7408	77	21	blue	blue	ADJ
cusj-7408	77	22	detection	detection	NOUN
cusj-7408	77	23	medium	medium	NOUN
cusj-7408	77	24	according	accord	VERB
cusj-7408	77	25	to	to	ADP
cusj-7408	77	26	manufacturer	manufacturer	NOUN
cusj-7408	77	27	’s	’s	PART
cusj-7408	77	28	instructions	instruction	NOUN
cusj-7408	77	29	.	.	PUNCT
cusj-7408	78	1	detection	detection	NOUN
cusj-7408	78	2	is	be	AUX
cusj-7408	78	3	a	a	DET
cusj-7408	78	4	measurement	measurement	NOUN
cusj-7408	78	5	of	of	ADP
cusj-7408	78	6	specific	specific	ADJ
cusj-7408	78	7	binding	binding	ADJ
cusj-7408	78	8	indicating	indicate	VERB
cusj-7408	78	9	extent	extent	NOUN
cusj-7408	78	10	of	of	ADP
cusj-7408	78	11	microbial	microbial	ADJ
cusj-7408	78	12	leakage	leakage	NOUN
cusj-7408	78	13	out	out	ADP
cusj-7408	78	14	of	of	ADP
cusj-7408	78	15	the	the	DET
cusj-7408	78	16	gut	gut	NOUN
cusj-7408	78	17	.	.	PUNCT
cusj-7408	79	1	statistical	statistical	ADJ
cusj-7408	79	2	analysis	analysis	NOUN
cusj-7408	79	3	data	datum	NOUN
cusj-7408	79	4	is	be	AUX
cusj-7408	79	5	presented	present	VERB
cusj-7408	79	6	as	as	ADP
cusj-7408	79	7	the	the	DET
cusj-7408	79	8	mean	mean	PROPN
cusj-7408	79	9	±	±	NUM
cusj-7408	79	10	standard	standard	ADJ
cusj-7408	79	11	deviation	deviation	NOUN
cusj-7408	79	12	.	.	PUNCT
cusj-7408	80	1	mann	mann	PROPN
cusj-7408	80	2	-	-	PUNCT
cusj-7408	80	3	whitney	whitney	PROPN
cusj-7408	80	4	u	u	NOUN
cusj-7408	80	5	-	-	NOUN
cusj-7408	80	6	tests	test	NOUN
cusj-7408	80	7	were	be	AUX
cusj-7408	80	8	per9	per9	PROPN
cusj-7408	80	9	columbia	columbia	PROPN
cusj-7408	80	10	undergraduate	undergraduate	PROPN
cusj-7408	80	11	science	science	PROPN
cusj-7408	80	12	journal	journal	PROPN
cusj-7408	80	13	vol	vol	NOUN
cusj-7408	80	14	.	.	PROPN
cusj-7408	80	15	15	15	NUM
cusj-7408	80	16	,	,	PUNCT
cusj-7408	80	17	2021	2021	NUM
cusj-7408	80	18	pinker	pinker	PROPN
cusj-7408	80	19	et	et	PROPN
cusj-7408	80	20	.	.	PUNCT
cusj-7408	81	1	al	al	PROPN
cusj-7408	81	2	.	.	PROPN
cusj-7408	81	3	formed	form	VERB
cusj-7408	81	4	to	to	PART
cusj-7408	81	5	compare	compare	VERB
cusj-7408	81	6	groups	group	NOUN
cusj-7408	81	7	.	.	PUNCT
cusj-7408	82	1	anova	anova	PROPN
cusj-7408	82	2	with	with	ADP
cusj-7408	82	3	post	post	X
cusj-7408	82	4	hoc	hoc	X
cusj-7408	82	5	test	test	NOUN
cusj-7408	82	6	was	be	AUX
cusj-7408	82	7	used	use	VERB
cusj-7408	82	8	for	for	ADP
cusj-7408	82	9	comparison	comparison	NOUN
cusj-7408	82	10	between	between	ADP
cusj-7408	82	11	multiple	multiple	ADJ
cusj-7408	82	12	groups	group	NOUN
cusj-7408	82	13	with	with	ADP
cusj-7408	82	14	a	a	DET
cusj-7408	82	15	bonferroni	bonferroni	NOUN
cusj-7408	82	16	correction	correction	NOUN
cusj-7408	82	17	.	.	PUNCT
cusj-7408	83	1	p	p	X
cusj-7408	83	2	<	<	X
cusj-7408	83	3	0.05	0.05	NUM
cusj-7408	83	4	and	and	CCONJ
cusj-7408	83	5	q	q	NOUN
cusj-7408	83	6	<	<	X
cusj-7408	83	7	0.1	0.1	NUM
cusj-7408	83	8	were	be	AUX
cusj-7408	83	9	the	the	DET
cusj-7408	83	10	threshold	threshold	NOUN
cusj-7408	83	11	for	for	ADP
cusj-7408	83	12	being	be	AUX
cusj-7408	83	13	considered	consider	VERB
cusj-7408	83	14	significant	significant	ADJ
cusj-7408	83	15	.	.	PUNCT
cusj-7408	84	1	*	*	PUNCT
cusj-7408	84	2	p	p	X
cusj-7408	84	3	<	<	X
cusj-7408	84	4	0.05	0.05	NUM
cusj-7408	84	5	,	,	PUNCT
cusj-7408	84	6	*	*	PUNCT
cusj-7408	84	7	*	*	PUNCT
cusj-7408	84	8	p	p	X
cusj-7408	84	9	<	<	X
cusj-7408	84	10	0.01	0.01	NUM
cusj-7408	84	11	,	,	PUNCT
cusj-7408	84	12	*	*	PUNCT
cusj-7408	84	13	*	*	PUNCT
cusj-7408	84	14	*	*	PUNCT
cusj-7408	84	15	p	p	X
cusj-7408	84	16	<	<	X
cusj-7408	84	17	0.001	0.001	NUM
cusj-7408	84	18	,	,	PUNCT
cusj-7408	84	19	*	*	PUNCT
cusj-7408	84	20	*	*	PUNCT
cusj-7408	84	21	*	*	PUNCT
cusj-7408	84	22	*	*	PUNCT
cusj-7408	84	23	p	p	X
cusj-7408	84	24	<	<	X
cusj-7408	84	25	0.0001	0.0001	NUM
cusj-7408	84	26	.	.	PUNCT
cusj-7408	84	27	results	result	VERB
cusj-7408	84	28	state	state	NOUN
cusj-7408	84	29	of	of	ADP
cusj-7408	84	30	small	small	ADJ
cusj-7408	84	31	intestinal	intestinal	ADJ
cusj-7408	84	32	microbiome	microbiome	NOUN
cusj-7408	84	33	determines	determine	VERB
cusj-7408	84	34	epithelial	epithelial	ADJ
cusj-7408	84	35	barrier	barrier	NOUN
cusj-7408	84	36	function	function	NOUN
cusj-7408	84	37	with	with	ADP
cusj-7408	84	38	a	a	DET
cusj-7408	84	39	gf	gf	NOUN
cusj-7408	84	40	mouse	mouse	NOUN
cusj-7408	84	41	model	model	NOUN
cusj-7408	84	42	,	,	PUNCT
cusj-7408	84	43	we	we	PRON
cusj-7408	84	44	initially	initially	ADV
cusj-7408	84	45	set	set	VERB
cusj-7408	84	46	out	out	ADP
cusj-7408	84	47	to	to	PART
cusj-7408	84	48	establish	establish	VERB
cusj-7408	84	49	the	the	DET
cusj-7408	84	50	role	role	NOUN
cusj-7408	84	51	a	a	DET
cusj-7408	84	52	microbiome	microbiome	NOUN
cusj-7408	84	53	has	have	VERB
cusj-7408	84	54	on	on	ADP
cusj-7408	84	55	the	the	DET
cusj-7408	84	56	permeability	permeability	NOUN
cusj-7408	84	57	of	of	ADP
cusj-7408	84	58	the	the	DET
cusj-7408	84	59	small	small	ADJ
cusj-7408	84	60	intestine	intestine	ADJ
cusj-7408	84	61	epithelial	epithelial	ADJ
cusj-7408	84	62	barrier	barrier	NOUN
cusj-7408	84	63	.	.	PUNCT
cusj-7408	85	1	mice	mouse	NOUN
cusj-7408	85	2	underwent	undergo	VERB
cusj-7408	85	3	fecal	fecal	ADJ
cusj-7408	85	4	transplantation	transplantation	NOUN
cusj-7408	85	5	of	of	ADP
cusj-7408	85	6	either	either	CCONJ
cusj-7408	85	7	normal	normal	ADJ
cusj-7408	85	8	chow	chow	NOUN
cusj-7408	85	9	(	(	PUNCT
cusj-7408	85	10	nc	nc	PROPN
cusj-7408	85	11	)	)	PUNCT
cusj-7408	85	12	microbiome	microbiome	NOUN
cusj-7408	85	13	or	or	CCONJ
cusj-7408	85	14	high	high	ADJ
cusj-7408	85	15	fat	fat	ADJ
cusj-7408	85	16	diet	diet	NOUN
cusj-7408	85	17	(	(	PUNCT
cusj-7408	85	18	hfd	hfd	PROPN
cusj-7408	85	19	)	)	PUNCT
cusj-7408	85	20	fed	fed	PROPN
cusj-7408	85	21	donor	donor	NOUN
cusj-7408	85	22	specific	specific	ADJ
cusj-7408	85	23	pathogen	pathogen	NOUN
cusj-7408	85	24	free	free	ADJ
cusj-7408	85	25	(	(	PUNCT
cusj-7408	85	26	spf	spf	ADJ
cusj-7408	85	27	)	)	PUNCT
cusj-7408	85	28	microbiome	microbiome	NOUN
cusj-7408	85	29	,	,	PUNCT
cusj-7408	85	30	while	while	SCONJ
cusj-7408	85	31	the	the	DET
cusj-7408	85	32	control	control	NOUN
cusj-7408	85	33	group	group	NOUN
cusj-7408	85	34	received	receive	VERB
cusj-7408	85	35	phosphate	phosphate	ADJ
cusj-7408	85	36	buffered	buffer	VERB
cusj-7408	85	37	saline	saline	NOUN
cusj-7408	85	38	(	(	PUNCT
cusj-7408	85	39	pbs	pbs	PROPN
cusj-7408	85	40	)	)	PUNCT
cusj-7408	85	41	(	(	PUNCT
cusj-7408	85	42	figure	figure	NOUN
cusj-7408	85	43	1a	1a	NOUN
cusj-7408	85	44	)	)	PUNCT
cusj-7408	85	45	.	.	PUNCT
cusj-7408	86	1	small	small	ADJ
cusj-7408	86	2	intestine	intestine	NOUN
cusj-7408	86	3	samples	sample	NOUN
cusj-7408	86	4	were	be	AUX
cusj-7408	86	5	taken	take	VERB
cusj-7408	86	6	and	and	CCONJ
cusj-7408	86	7	epithelial	epithelial	ADJ
cusj-7408	86	8	resistance	resistance	NOUN
cusj-7408	86	9	was	be	AUX
cusj-7408	86	10	measured	measure	VERB
cusj-7408	86	11	with	with	ADP
cusj-7408	86	12	the	the	DET
cusj-7408	86	13	ussing	ussing	ADJ
cusj-7408	86	14	chamber	chamber	NOUN
cusj-7408	86	15	.	.	PUNCT
cusj-7408	87	1	interestingly	interestingly	ADV
cusj-7408	87	2	,	,	PUNCT
cusj-7408	87	3	mice	mouse	NOUN
cusj-7408	87	4	with	with	ADP
cusj-7408	87	5	hfd	hfd	PROPN
cusj-7408	87	6	microbiome	microbiome	PROPN
cusj-7408	87	7	showed	show	VERB
cusj-7408	87	8	increased	increase	VERB
cusj-7408	87	9	permeability	permeability	NOUN
cusj-7408	87	10	while	while	SCONJ
cusj-7408	87	11	mice	mouse	NOUN
cusj-7408	87	12	with	with	ADP
cusj-7408	87	13	pbs	pbs	PROPN
cusj-7408	87	14	(	(	PUNCT
cusj-7408	87	15	no	no	DET
cusj-7408	87	16	microbiome	microbiome	NOUN
cusj-7408	87	17	)	)	PUNCT
cusj-7408	87	18	showed	show	VERB
cusj-7408	87	19	reduced	reduced	ADJ
cusj-7408	87	20	permeability	permeability	NOUN
cusj-7408	87	21	(	(	PUNCT
cusj-7408	87	22	figure	figure	NOUN
cusj-7408	87	23	1b	1b	NUM
cusj-7408	87	24	)	)	PUNCT
cusj-7408	87	25	.	.	PUNCT
cusj-7408	88	1	together	together	ADV
cusj-7408	88	2	,	,	PUNCT
cusj-7408	88	3	this	this	DET
cusj-7408	88	4	data	datum	NOUN
cusj-7408	88	5	suggests	suggest	VERB
cusj-7408	88	6	that	that	SCONJ
cusj-7408	88	7	microbiome	microbiome	NOUN
cusj-7408	88	8	shaped	shape	VERB
cusj-7408	88	9	by	by	ADP
cusj-7408	88	10	diet	diet	NOUN
cusj-7408	88	11	is	be	AUX
cusj-7408	88	12	an	an	DET
cusj-7408	88	13	active	active	ADJ
cusj-7408	88	14	influencer	influencer	NOUN
cusj-7408	88	15	over	over	ADP
cusj-7408	88	16	intestinal	intestinal	ADJ
cusj-7408	88	17	permeability	permeability	NOUN
cusj-7408	88	18	.	.	PUNCT
cusj-7408	89	1	we	we	PRON
cusj-7408	89	2	next	next	ADV
cusj-7408	89	3	set	set	VERB
cusj-7408	89	4	out	out	ADP
cusj-7408	89	5	to	to	PART
cusj-7408	89	6	further	far	ADV
cusj-7408	89	7	analyze	analyze	VERB
cusj-7408	89	8	which	which	DET
cusj-7408	89	9	subsets	subset	NOUN
cusj-7408	89	10	of	of	ADP
cusj-7408	89	11	bacteria	bacteria	NOUN
cusj-7408	89	12	within	within	ADP
cusj-7408	89	13	the	the	DET
cusj-7408	89	14	microbiome	microbiome	NOUN
cusj-7408	89	15	community	community	NOUN
cusj-7408	89	16	are	be	AUX
cusj-7408	89	17	most	most	ADV
cusj-7408	89	18	influential	influential	ADJ
cusj-7408	89	19	in	in	ADP
cusj-7408	89	20	barrier	barrier	NOUN
cusj-7408	89	21	function	function	NOUN
cusj-7408	89	22	modulation	modulation	NOUN
cusj-7408	89	23	.	.	PUNCT
cusj-7408	90	1	with	with	ADP
cusj-7408	90	2	an	an	DET
cusj-7408	90	3	antibiotic	antibiotic	ADJ
cusj-7408	90	4	murine	murine	ADJ
cusj-7408	90	5	model	model	NOUN
cusj-7408	90	6	,	,	PUNCT
cusj-7408	90	7	we	we	PRON
cusj-7408	90	8	could	could	AUX
cusj-7408	90	9	target	target	VERB
cusj-7408	90	10	specific	specific	ADJ
cusj-7408	90	11	subsets	subset	NOUN
cusj-7408	90	12	of	of	ADP
cusj-7408	90	13	bacteria	bacteria	NOUN
cusj-7408	90	14	to	to	PART
cusj-7408	90	15	determine	determine	VERB
cusj-7408	90	16	the	the	DET
cusj-7408	90	17	impact	impact	NOUN
cusj-7408	90	18	the	the	DET
cusj-7408	90	19	presence	presence	NOUN
cusj-7408	90	20	or	or	CCONJ
cusj-7408	90	21	lack	lack	NOUN
cusj-7408	90	22	thereof	thereof	ADV
cusj-7408	90	23	has	have	VERB
cusj-7408	90	24	on	on	ADP
cusj-7408	90	25	epithelial	epithelial	ADJ
cusj-7408	90	26	permeability	permeability	NOUN
cusj-7408	90	27	in	in	ADP
cusj-7408	90	28	the	the	DET
cusj-7408	90	29	intestine	intestine	NOUN
cusj-7408	90	30	.	.	PUNCT
cusj-7408	91	1	we	we	PRON
cusj-7408	91	2	treated	treat	VERB
cusj-7408	91	3	5	5	NUM
cusj-7408	91	4	groups	group	NOUN
cusj-7408	91	5	of	of	ADP
cusj-7408	91	6	wt	wt	PRON
cusj-7408	91	7	mice	mouse	NOUN
cusj-7408	91	8	,	,	PUNCT
cusj-7408	91	9	fed	feed	VERB
cusj-7408	91	10	with	with	ADP
cusj-7408	91	11	normal	normal	ADJ
cusj-7408	91	12	chow	chow	NOUN
cusj-7408	91	13	,	,	PUNCT
cusj-7408	91	14	with	with	ADP
cusj-7408	91	15	selective	selective	ADJ
cusj-7408	91	16	antibiotics	antibiotic	NOUN
cusj-7408	91	17	that	that	PRON
cusj-7408	91	18	target	target	VERB
cusj-7408	91	19	specific	specific	ADJ
cusj-7408	91	20	members	member	NOUN
cusj-7408	91	21	of	of	ADP
cusj-7408	91	22	microbiome	microbiome	NOUN
cusj-7408	91	23	:	:	PUNCT
cusj-7408	91	24	metronidazole	metronidazole	NOUN
cusj-7408	91	25	(	(	PUNCT
cusj-7408	91	26	anaerobic	anaerobic	ADJ
cusj-7408	91	27	bacteria	bacteria	NOUN
cusj-7408	91	28	)	)	PUNCT
cusj-7408	91	29	,	,	PUNCT
cusj-7408	91	30	vancomycin	vancomycin	PROPN
cusj-7408	91	31	(	(	PUNCT
cusj-7408	91	32	gram	gram	NOUN
cusj-7408	91	33	-	-	PUNCT
cusj-7408	91	34	positive	positive	ADJ
cusj-7408	91	35	bacteria	bacteria	NOUN
cusj-7408	91	36	)	)	PUNCT
cusj-7408	91	37	,	,	PUNCT
cusj-7408	91	38	ampicillin	ampicillin	NOUN
cusj-7408	91	39	(	(	PUNCT
cusj-7408	91	40	broad	broad	ADJ
cusj-7408	91	41	spectrum	spectrum	NOUN
cusj-7408	91	42	)	)	PUNCT
cusj-7408	91	43	,	,	PUNCT
cusj-7408	91	44	neomycin	neomycin	PROPN
cusj-7408	91	45	(	(	PUNCT
cusj-7408	91	46	gram	gram	NOUN
cusj-7408	91	47	-	-	PUNCT
cusj-7408	91	48	negative	negative	ADJ
cusj-7408	91	49	bacteria	bacteria	NOUN
cusj-7408	91	50	)	)	PUNCT
cusj-7408	91	51	,	,	PUNCT
cusj-7408	91	52	or	or	CCONJ
cusj-7408	91	53	a	a	DET
cusj-7408	91	54	combination	combination	NOUN
cusj-7408	91	55	of	of	ADP
cusj-7408	91	56	all	all	DET
cusj-7408	91	57	four	four	NUM
cusj-7408	91	58	for	for	ADP
cusj-7408	91	59	a	a	DET
cusj-7408	91	60	duration	duration	NOUN
cusj-7408	91	61	of	of	ADP
cusj-7408	91	62	3	3	NUM
cusj-7408	91	63	weeks	week	NOUN
cusj-7408	91	64	delivered	deliver	VERB
cusj-7408	91	65	in	in	ADP
cusj-7408	91	66	their	their	PRON
cusj-7408	91	67	drinking	drinking	NOUN
cusj-7408	91	68	water	water	NOUN
cusj-7408	91	69	(	(	PUNCT
cusj-7408	91	70	figure	figure	NOUN
cusj-7408	91	71	1c	1c	NOUN
cusj-7408	91	72	)	)	PUNCT
cusj-7408	91	73	.	.	PUNCT
cusj-7408	92	1	the	the	DET
cusj-7408	92	2	group	group	NOUN
cusj-7408	92	3	containing	contain	VERB
cusj-7408	92	4	all	all	DET
cusj-7408	92	5	four	four	NUM
cusj-7408	92	6	antibiotics	antibiotic	NOUN
cusj-7408	92	7	is	be	AUX
cusj-7408	92	8	a	a	DET
cusj-7408	92	9	crude	crude	ADJ
cusj-7408	92	10	simulation	simulation	NOUN
cusj-7408	92	11	of	of	ADP
cusj-7408	92	12	the	the	DET
cusj-7408	92	13	germ	germ	NOUN
cusj-7408	92	14	-	-	PUNCT
cusj-7408	92	15	free	free	ADJ
cusj-7408	92	16	mouse	mouse	NOUN
cusj-7408	92	17	model	model	NOUN
cusj-7408	92	18	.	.	PUNCT
cusj-7408	93	1	after	after	ADP
cusj-7408	93	2	3	3	NUM
cusj-7408	93	3	weeks	week	NOUN
cusj-7408	93	4	,	,	PUNCT
cusj-7408	93	5	a	a	DET
cusj-7408	93	6	fitc	fitc	NOUN
cusj-7408	93	7	-	-	PUNCT
cusj-7408	93	8	dextran	dextran	VERB
cusj-7408	93	9	assay	assay	NOUN
cusj-7408	93	10	was	be	AUX
cusj-7408	93	11	performed	perform	VERB
cusj-7408	93	12	,	,	PUNCT
cusj-7408	93	13	which	which	PRON
cusj-7408	93	14	entails	entail	VERB
cusj-7408	93	15	orally	orally	ADV
cusj-7408	93	16	administering	administer	VERB
cusj-7408	93	17	mice	mouse	NOUN
cusj-7408	93	18	with	with	ADP
cusj-7408	93	19	fluorescent	fluorescent	ADJ
cusj-7408	93	20	dye	dye	NOUN
cusj-7408	93	21	coated	coat	VERB
cusj-7408	93	22	4	4	NUM
cusj-7408	93	23	kda	kda	NOUN
cusj-7408	93	24	beads	bead	NOUN
cusj-7408	93	25	and	and	CCONJ
cusj-7408	93	26	measuring	measure	VERB
cusj-7408	93	27	fluorescence	fluorescence	NOUN
cusj-7408	93	28	in	in	ADP
cusj-7408	93	29	the	the	DET
cusj-7408	93	30	peripheral	peripheral	ADJ
cusj-7408	93	31	blood	blood	NOUN
cusj-7408	93	32	,	,	PUNCT
cusj-7408	93	33	at	at	ADP
cusj-7408	93	34	zt14	zt14	PROPN
cusj-7408	93	35	,	,	PUNCT
cusj-7408	93	36	as	as	ADP
cusj-7408	93	37	a	a	DET
cusj-7408	93	38	proxy	proxy	NOUN
cusj-7408	93	39	for	for	ADP
cusj-7408	93	40	epithelial	epithelial	ADJ
cusj-7408	93	41	barrier	barrier	NOUN
cusj-7408	93	42	permeability	permeability	NOUN
cusj-7408	93	43	.	.	PUNCT
cusj-7408	94	1	significant	significant	ADJ
cusj-7408	94	2	reduction	reduction	NOUN
cusj-7408	94	3	in	in	ADP
cusj-7408	94	4	optical	optical	ADJ
cusj-7408	94	5	density	density	NOUN
cusj-7408	94	6	(	(	PUNCT
cusj-7408	94	7	od	od	NOUN
cusj-7408	94	8	)	)	PUNCT
cusj-7408	94	9	was	be	AUX
cusj-7408	94	10	observed	observe	VERB
cusj-7408	94	11	in	in	ADP
cusj-7408	94	12	four	four	NUM
cusj-7408	94	13	of	of	ADP
cusj-7408	94	14	the	the	DET
cusj-7408	94	15	antibiotic	antibiotic	ADJ
cusj-7408	94	16	groups	group	NOUN
cusj-7408	94	17	compared	compare	VERB
cusj-7408	94	18	to	to	ADP
cusj-7408	94	19	the	the	DET
cusj-7408	94	20	control	control	NOUN
cusj-7408	94	21	(	(	PUNCT
cusj-7408	94	22	figure	figure	NOUN
cusj-7408	94	23	1d	1d	NUM
cusj-7408	94	24	)	)	PUNCT
cusj-7408	94	25	.	.	PUNCT
cusj-7408	95	1	additionally	additionally	ADV
cusj-7408	95	2	,	,	PUNCT
cusj-7408	95	3	vancomycin	vancomycin	PROPN
cusj-7408	95	4	treated	treat	VERB
cusj-7408	95	5	mice	mouse	NOUN
cusj-7408	95	6	had	have	VERB
cusj-7408	95	7	significantly	significantly	ADV
cusj-7408	95	8	higher	high	ADJ
cusj-7408	95	9	od	od	ADV
cusj-7408	95	10	than	than	ADP
cusj-7408	95	11	neomycin	neomycin	PROPN
cusj-7408	95	12	and	and	CCONJ
cusj-7408	95	13	metronidazole	metronidazole	NOUN
cusj-7408	95	14	groups	group	NOUN
cusj-7408	95	15	(	(	PUNCT
cusj-7408	95	16	figure	figure	NOUN
cusj-7408	95	17	1d	1d	NUM
cusj-7408	95	18	)	)	PUNCT
cusj-7408	95	19	.	.	PUNCT
cusj-7408	96	1	the	the	DET
cusj-7408	96	2	lack	lack	NOUN
cusj-7408	96	3	of	of	ADP
cusj-7408	96	4	a	a	DET
cusj-7408	96	5	significant	significant	ADJ
cusj-7408	96	6	reduction	reduction	NOUN
cusj-7408	96	7	in	in	ADP
cusj-7408	96	8	permeability	permeability	NOUN
cusj-7408	96	9	in	in	ADP
cusj-7408	96	10	the	the	DET
cusj-7408	96	11	combination	combination	NOUN
cusj-7408	96	12	treatment	treatment	NOUN
cusj-7408	96	13	,	,	PUNCT
cusj-7408	96	14	containing	contain	VERB
cusj-7408	96	15	all	all	DET
cusj-7408	96	16	four	four	NUM
cusj-7408	96	17	antibiotics	antibiotic	NOUN
cusj-7408	96	18	,	,	PUNCT
cusj-7408	96	19	was	be	AUX
cusj-7408	96	20	likely	likely	ADJ
cusj-7408	96	21	due	due	ADP
cusj-7408	96	22	to	to	ADP
cusj-7408	96	23	outliers	outlier	NOUN
cusj-7408	96	24	.	.	PUNCT
cusj-7408	97	1	two	two	NUM
cusj-7408	97	2	days	day	NOUN
cusj-7408	97	3	after	after	SCONJ
cusj-7408	97	4	blood	blood	NOUN
cusj-7408	97	5	was	be	AUX
cusj-7408	97	6	taken	take	VERB
cusj-7408	97	7	,	,	PUNCT
cusj-7408	97	8	and	and	CCONJ
cusj-7408	97	9	fluorescence	fluorescence	NOUN
cusj-7408	97	10	was	be	AUX
cusj-7408	97	11	no	no	ADV
cusj-7408	97	12	longer	long	ADV
cusj-7408	97	13	detectable	detectable	ADJ
cusj-7408	97	14	,	,	PUNCT
cusj-7408	97	15	mice	mouse	NOUN
cusj-7408	97	16	were	be	AUX
cusj-7408	97	17	sacrificed	sacrifice	VERB
cusj-7408	97	18	,	,	PUNCT
cusj-7408	97	19	at	at	ADP
cusj-7408	97	20	zt14	zt14	PROPN
cusj-7408	97	21	,	,	PUNCT
cusj-7408	97	22	and	and	CCONJ
cusj-7408	97	23	small	small	ADJ
cusj-7408	97	24	intestine	intestine	NOUN
cusj-7408	97	25	samples	sample	NOUN
cusj-7408	97	26	were	be	AUX
cusj-7408	97	27	removed	remove	VERB
cusj-7408	97	28	for	for	ADP
cusj-7408	97	29	the	the	DET
cusj-7408	97	30	ussing	ussing	ADJ
cusj-7408	97	31	chamber	chamber	NOUN
cusj-7408	97	32	measurements	measurement	NOUN
cusj-7408	97	33	.	.	PUNCT
cusj-7408	98	1	only	only	ADV
cusj-7408	98	2	the	the	DET
cusj-7408	98	3	jejunum	jejunum	ADJ
cusj-7408	98	4	region	region	NOUN
cusj-7408	98	5	of	of	ADP
cusj-7408	98	6	the	the	DET
cusj-7408	98	7	small	small	ADJ
cusj-7408	98	8	intestine	intestine	NOUN
cusj-7408	98	9	was	be	AUX
cusj-7408	98	10	used	use	VERB
cusj-7408	98	11	for	for	ADP
cusj-7408	98	12	ussing	usse	VERB
cusj-7408	98	13	chamber	chamber	NOUN
cusj-7408	98	14	.	.	PUNCT
cusj-7408	99	1	all	all	DET
cusj-7408	99	2	five	five	NUM
cusj-7408	99	3	antibiotic	antibiotic	ADJ
cusj-7408	99	4	groups	group	NOUN
cusj-7408	99	5	showed	show	VERB
cusj-7408	99	6	significantly	significantly	ADV
cusj-7408	99	7	reduced	reduce	VERB
cusj-7408	99	8	permeability	permeability	NOUN
cusj-7408	99	9	and	and	CCONJ
cusj-7408	99	10	vancomycin	vancomycin	PROPN
cusj-7408	99	11	,	,	PUNCT
cusj-7408	99	12	again	again	ADV
cusj-7408	99	13	,	,	PUNCT
cusj-7408	99	14	showed	show	VERB
cusj-7408	99	15	higher	high	ADJ
cusj-7408	99	16	permeability	permeability	NOUN
cusj-7408	99	17	than	than	ADP
cusj-7408	99	18	two	two	NUM
cusj-7408	99	19	of	of	ADP
cusj-7408	99	20	the	the	DET
cusj-7408	99	21	other	other	ADJ
cusj-7408	99	22	antibiotic	antibiotic	ADJ
cusj-7408	99	23	groups	group	NOUN
cusj-7408	99	24	(	(	PUNCT
cusj-7408	99	25	figure	figure	NOUN
cusj-7408	99	26	1e	1e	NUM
cusj-7408	99	27	)	)	PUNCT
cusj-7408	99	28	.	.	PUNCT
cusj-7408	100	1	together	together	ADV
cusj-7408	100	2	,	,	PUNCT
cusj-7408	100	3	these	these	DET
cusj-7408	100	4	results	result	NOUN
cusj-7408	100	5	uncover	uncover	VERB
cusj-7408	100	6	that	that	SCONJ
cusj-7408	100	7	the	the	DET
cusj-7408	100	8	state	state	NOUN
cusj-7408	100	9	of	of	ADP
cusj-7408	100	10	microbial	microbial	ADJ
cusj-7408	100	11	composition	composition	NOUN
cusj-7408	100	12	directly	directly	ADV
cusj-7408	100	13	alters	alter	VERB
cusj-7408	100	14	the	the	DET
cusj-7408	100	15	barrier	barrier	NOUN
cusj-7408	100	16	integrity	integrity	NOUN
cusj-7408	100	17	in	in	ADP
cusj-7408	100	18	the	the	DET
cusj-7408	100	19	small	small	ADJ
cusj-7408	100	20	intestine	intestine	NOUN
cusj-7408	100	21	and	and	CCONJ
cusj-7408	100	22	the	the	DET
cusj-7408	100	23	entire	entire	ADJ
cusj-7408	100	24	system	system	NOUN
cusj-7408	100	25	.	.	PUNCT
cusj-7408	101	1	additionally	additionally	ADV
cusj-7408	101	2	,	,	PUNCT
cusj-7408	101	3	vancomycin	vancomycin	PROPN
cusj-7408	101	4	-	-	PUNCT
cusj-7408	101	5	treated	treat	VERB
cusj-7408	101	6	groups	group	NOUN
cusj-7408	101	7	experienced	experience	VERB
cusj-7408	101	8	the	the	DET
cusj-7408	101	9	smallest	small	ADJ
cusj-7408	101	10	reduction	reduction	NOUN
cusj-7408	101	11	in	in	ADP
cusj-7408	101	12	permeability	permeability	NOUN
cusj-7408	101	13	suggesting	suggest	VERB
cusj-7408	101	14	,	,	PUNCT
cusj-7408	101	15	that	that	SCONJ
cusj-7408	101	16	gram	gram	NOUN
cusj-7408	101	17	-	-	PUNCT
cusj-7408	101	18	positive	positive	ADJ
cusj-7408	101	19	bacteria	bacteria	NOUN
cusj-7408	101	20	play	play	VERB
cusj-7408	101	21	the	the	DET
cusj-7408	101	22	smallest	small	ADJ
cusj-7408	101	23	role	role	NOUN
cusj-7408	101	24	in	in	ADP
cusj-7408	101	25	intestinal	intestinal	ADJ
cusj-7408	101	26	epithelial	epithelial	ADJ
cusj-7408	101	27	barrier	barrier	NOUN
cusj-7408	101	28	function	function	NOUN
cusj-7408	101	29	compared	compare	VERB
cusj-7408	101	30	to	to	ADP
cusj-7408	101	31	other	other	ADJ
cusj-7408	101	32	bacterial	bacterial	ADJ
cusj-7408	101	33	subtypes	subtype	NOUN
cusj-7408	101	34	in	in	ADP
cusj-7408	101	35	the	the	DET
cusj-7408	101	36	gut	gut	NOUN
cusj-7408	101	37	microbiome	microbiome	NOUN
cusj-7408	101	38	.	.	PUNCT
cusj-7408	102	1	genetic	genetic	ADJ
cusj-7408	102	2	and	and	CCONJ
cusj-7408	102	3	environmental	environmental	ADJ
cusj-7408	102	4	disruption	disruption	NOUN
cusj-7408	102	5	of	of	ADP
cusj-7408	102	6	circadian	circadian	ADJ
cusj-7408	102	7	clocks	clock	NOUN
cusj-7408	102	8	impacts	impact	VERB
cusj-7408	102	9	epithelial	epithelial	ADJ
cusj-7408	102	10	barrier	barrier	NOUN
cusj-7408	102	11	integrity	integrity	NOUN
cusj-7408	102	12	it	it	PRON
cusj-7408	102	13	has	have	AUX
cusj-7408	102	14	been	be	AUX
cusj-7408	102	15	shown	show	VERB
cusj-7408	102	16	that	that	SCONJ
cusj-7408	102	17	a	a	DET
cusj-7408	102	18	functional	functional	ADJ
cusj-7408	102	19	circadian	circadian	ADJ
cusj-7408	102	20	clock	clock	NOUN
cusj-7408	102	21	of	of	ADP
cusj-7408	102	22	a	a	DET
cusj-7408	102	23	host	host	NOUN
cusj-7408	102	24	is	be	AUX
cusj-7408	102	25	required	require	VERB
cusj-7408	102	26	for	for	ADP
cusj-7408	102	27	normal	normal	ADJ
cusj-7408	102	28	diurnal	diurnal	ADJ
cusj-7408	102	29	rhythmicity	rhythmicity	NOUN
cusj-7408	102	30	in	in	ADP
cusj-7408	102	31	microbiota	microbiota	NOUN
cusj-7408	102	32	composition	composition	NOUN
cusj-7408	102	33	and	and	CCONJ
cusj-7408	102	34	function	function	NOUN
cusj-7408	102	35	‎[8	‎[8	ADV
cusj-7408	102	36	]	]	PUNCT
cusj-7408	102	37	.	.	PUNCT
cusj-7408	103	1	building	build	VERB
cusj-7408	103	2	off	off	ADP
cusj-7408	103	3	our	our	PRON
cusj-7408	103	4	previous	previous	ADJ
cusj-7408	103	5	observations	observation	NOUN
cusj-7408	103	6	,	,	PUNCT
cusj-7408	103	7	the	the	DET
cusj-7408	103	8	next	next	ADJ
cusj-7408	103	9	step	step	NOUN
cusj-7408	103	10	is	be	AUX
cusj-7408	103	11	to	to	PART
cusj-7408	103	12	examine	examine	VERB
cusj-7408	103	13	if	if	SCONJ
cusj-7408	103	14	circadian	circadian	ADJ
cusj-7408	103	15	clock	clock	VERB
cusj-7408	103	16	disruption	disruption	NOUN
cusj-7408	103	17	will	will	AUX
cusj-7408	103	18	likewise	likewise	ADV
cusj-7408	103	19	compromise	compromise	VERB
cusj-7408	103	20	the	the	DET
cusj-7408	103	21	intestinal	intestinal	ADJ
cusj-7408	103	22	epithelial	epithelial	ADJ
cusj-7408	103	23	barrier	barrier	NOUN
cusj-7408	103	24	.	.	PUNCT
cusj-7408	104	1	testing	testing	NOUN
cusj-7408	104	2	of	of	ADP
cusj-7408	104	3	per1/2-/mice	per1/2-/mice	PROPN
cusj-7408	104	4	,	,	PUNCT
cusj-7408	104	5	genetically	genetically	ADV
cusj-7408	104	6	deficient	deficient	ADJ
cusj-7408	104	7	in	in	ADP
cusj-7408	104	8	a	a	DET
cusj-7408	104	9	functional	functional	ADJ
cusj-7408	104	10	host	host	NOUN
cusj-7408	104	11	clock	clock	NOUN
cusj-7408	104	12	,	,	PUNCT
cusj-7408	104	13	has	have	AUX
cusj-7408	104	14	previously	previously	ADV
cusj-7408	104	15	shown	show	VERB
cusj-7408	104	16	to	to	PART
cusj-7408	104	17	disrupt	disrupt	VERB
cusj-7408	104	18	diurnal	diurnal	ADJ
cusj-7408	104	19	rhythmicity	rhythmicity	NOUN
cusj-7408	104	20	in	in	ADP
cusj-7408	104	21	microbiota	microbiota	NOUN
cusj-7408	104	22	composition	composition	NOUN
cusj-7408	104	23	‎[8	‎[8	ADV
cusj-7408	104	24	]	]	PUNCT
cusj-7408	104	25	.	.	PUNCT
cusj-7408	105	1	with	with	ADP
cusj-7408	105	2	our	our	PRON
cusj-7408	105	3	own	own	ADJ
cusj-7408	105	4	group	group	NOUN
cusj-7408	105	5	of	of	ADP
cusj-7408	105	6	per1/2-/mice	per1/2-/mice	PROPN
cusj-7408	105	7	,	,	PUNCT
cusj-7408	105	8	we	we	PRON
cusj-7408	105	9	ran	run	VERB
cusj-7408	105	10	a	a	DET
cusj-7408	105	11	fitc	fitc	NOUN
cusj-7408	105	12	-	-	PUNCT
cusj-7408	105	13	dextran	dextran	VERB
cusj-7408	105	14	assay	assay	NOUN
cusj-7408	105	15	.	.	PUNCT
cusj-7408	106	1	10	10	NUM
cusj-7408	106	2	columbia	columbia	PROPN
cusj-7408	106	3	undergraduate	undergraduate	PROPN
cusj-7408	106	4	science	science	PROPN
cusj-7408	106	5	journal	journal	PROPN
cusj-7408	106	6	vol	vol	NOUN
cusj-7408	106	7	.	.	PROPN
cusj-7408	106	8	15	15	NUM
cusj-7408	106	9	,	,	PUNCT
cusj-7408	106	10	2021	2021	NUM
cusj-7408	106	11	pinker	pinker	PROPN
cusj-7408	106	12	et	et	PROPN
cusj-7408	106	13	.	.	PUNCT
cusj-7408	107	1	al	al	PROPN
cusj-7408	107	2	.	.	PUNCT
cusj-7408	108	1	the	the	DET
cusj-7408	108	2	od	od	NOUN
cusj-7408	108	3	for	for	ADP
cusj-7408	108	4	per	per	ADP
cusj-7408	108	5	1/2-/was	1/2-/was	NUM
cusj-7408	108	6	significantly	significantly	ADV
cusj-7408	108	7	higher	higher	ADV
cusj-7408	108	8	(	(	PUNCT
cusj-7408	108	9	figure	figure	NOUN
cusj-7408	108	10	2a	2a	NUM
cusj-7408	108	11	)	)	PUNCT
cusj-7408	108	12	demonstrating	demonstrate	VERB
cusj-7408	108	13	that	that	SCONJ
cusj-7408	108	14	circadian	circadian	ADJ
cusj-7408	108	15	clock	clock	NOUN
cusj-7408	108	16	disruption	disruption	NOUN
cusj-7408	108	17	results	result	NOUN
cusj-7408	108	18	in	in	ADP
cusj-7408	108	19	increased	increase	VERB
cusj-7408	108	20	intestinal	intestinal	ADJ
cusj-7408	108	21	permeability	permeability	NOUN
cusj-7408	108	22	,	,	PUNCT
cusj-7408	108	23	a	a	DET
cusj-7408	108	24	feature	feature	NOUN
cusj-7408	108	25	of	of	ADP
cusj-7408	108	26	a	a	DET
cusj-7408	108	27	“	"	PUNCT
cusj-7408	108	28	leaky	leaky	ADJ
cusj-7408	108	29	gut	gut	NOUN
cusj-7408	108	30	”	"	PUNCT
cusj-7408	108	31	syndrome	syndrome	NOUN
cusj-7408	108	32	.	.	PUNCT
cusj-7408	109	1	environmental	environmental	ADJ
cusj-7408	109	2	clock	clock	NOUN
cusj-7408	109	3	disruptions	disruption	NOUN
cusj-7408	109	4	such	such	ADJ
cusj-7408	109	5	as	as	ADP
cusj-7408	109	6	chronic	chronic	ADJ
cusj-7408	109	7	jet	jet	NOUN
cusj-7408	109	8	lag	lag	NOUN
cusj-7408	109	9	and	and	CCONJ
cusj-7408	109	10	shift	shift	NOUN
cusj-7408	109	11	work	work	NOUN
cusj-7408	109	12	are	be	AUX
cusj-7408	109	13	behavioral	behavioral	ADJ
cusj-7408	109	14	patterns	pattern	NOUN
cusj-7408	109	15	associated	associate	VERB
cusj-7408	109	16	with	with	ADP
cusj-7408	109	17	an	an	DET
cusj-7408	109	18	increased	increase	VERB
cusj-7408	109	19	risk	risk	NOUN
cusj-7408	109	20	for	for	ADP
cusj-7408	109	21	obesity	obesity	NOUN
cusj-7408	109	22	,	,	PUNCT
cusj-7408	109	23	diabetes	diabetes	NOUN
cusj-7408	109	24	and	and	CCONJ
cusj-7408	109	25	cardiovascular	cardiovascular	ADJ
cusj-7408	109	26	disease	disease	NOUN
cusj-7408	109	27	[	[	X
cusj-7408	109	28	23][18][14][16][24	23][18][14][16][24	NUM
cusj-7408	109	29	]	]	PUNCT
cusj-7408	109	30	.	.	PUNCT
cusj-7408	110	1	it	it	PRON
cusj-7408	110	2	has	have	AUX
cusj-7408	110	3	been	be	AUX
cusj-7408	110	4	previously	previously	ADV
cusj-7408	110	5	established	establish	VERB
cusj-7408	110	6	that	that	SCONJ
cusj-7408	110	7	a	a	DET
cusj-7408	110	8	loss	loss	NOUN
cusj-7408	110	9	of	of	ADP
cusj-7408	110	10	microbiota	microbiota	NOUN
cusj-7408	110	11	oscillations	oscillation	NOUN
cusj-7408	110	12	and	and	CCONJ
cusj-7408	110	13	dysbiosis	dysbiosis	NOUN
cusj-7408	110	14	is	be	AUX
cusj-7408	110	15	associated	associate	VERB
cusj-7408	110	16	with	with	ADP
cusj-7408	110	17	jet	jet	NOUN
cusj-7408	110	18	lag	lag	NOUN
cusj-7408	110	19	in	in	ADP
cusj-7408	110	20	mice	mouse	NOUN
cusj-7408	110	21	[	[	X
cusj-7408	110	22	8	8	NUM
cusj-7408	110	23	]	]	PUNCT
cusj-7408	110	24	.	.	PUNCT
cusj-7408	111	1	so	so	ADV
cusj-7408	111	2	,	,	PUNCT
cusj-7408	111	3	we	we	PRON
cusj-7408	111	4	set	set	VERB
cusj-7408	111	5	out	out	ADP
cusj-7408	111	6	to	to	PART
cusj-7408	111	7	learn	learn	VERB
cusj-7408	111	8	if	if	SCONJ
cusj-7408	111	9	these	these	DET
cusj-7408	111	10	losses	loss	NOUN
cusj-7408	111	11	of	of	ADP
cusj-7408	111	12	oscillations	oscillation	NOUN
cusj-7408	111	13	and	and	CCONJ
cusj-7408	111	14	dysbioses	dysbiose	NOUN
cusj-7408	111	15	,	,	PUNCT
cusj-7408	111	16	in	in	ADP
cusj-7408	111	17	jet	jet	NOUN
cusj-7408	111	18	lag	lag	NOUN
cusj-7408	111	19	mice	mouse	NOUN
cusj-7408	111	20	,	,	PUNCT
cusj-7408	111	21	also	also	ADV
cusj-7408	111	22	impact	impact	VERB
cusj-7408	111	23	barrier	barrier	NOUN
cusj-7408	111	24	function	function	NOUN
cusj-7408	111	25	in	in	ADP
cusj-7408	111	26	the	the	DET
cusj-7408	111	27	intestinal	intestinal	ADJ
cusj-7408	111	28	epithelial	epithelial	ADJ
cusj-7408	111	29	barrier	barrier	NOUN
cusj-7408	111	30	.	.	PUNCT
cusj-7408	112	1	prior	prior	ADV
cusj-7408	112	2	to	to	ADP
cusj-7408	112	3	our	our	PRON
cusj-7408	112	4	jet	jet	NOUN
cusj-7408	112	5	lag	lag	NOUN
cusj-7408	112	6	experiment	experiment	NOUN
cusj-7408	112	7	,	,	PUNCT
cusj-7408	112	8	we	we	PRON
cusj-7408	112	9	performed	perform	VERB
cusj-7408	112	10	a	a	DET
cusj-7408	112	11	24	24	NUM
cusj-7408	112	12	-	-	PUNCT
cusj-7408	112	13	hour	hour	NOUN
cusj-7408	112	14	circadian	circadian	ADJ
cusj-7408	112	15	experiment	experiment	NOUN
cusj-7408	112	16	on	on	ADP
cusj-7408	112	17	wt	wt	NOUN
cusj-7408	112	18	mice	mouse	NOUN
cusj-7408	112	19	measuring	measure	VERB
cusj-7408	112	20	intestinal	intestinal	ADJ
cusj-7408	112	21	permeability	permeability	NOUN
cusj-7408	112	22	with	with	ADP
cusj-7408	112	23	two	two	NUM
cusj-7408	112	24	independent	independent	ADJ
cusj-7408	112	25	methods	method	NOUN
cusj-7408	112	26	–	–	PUNCT
cusj-7408	112	27	one	one	NUM
cusj-7408	112	28	measuring	measure	VERB
cusj-7408	112	29	the	the	DET
cusj-7408	112	30	electrical	electrical	ADJ
cusj-7408	112	31	permeability	permeability	NOUN
cusj-7408	112	32	of	of	ADP
cusj-7408	112	33	the	the	DET
cusj-7408	112	34	epithelium	epithelium	NOUN
cusj-7408	112	35	to	to	ADP
cusj-7408	112	36	ions	ion	NOUN
cusj-7408	112	37	(	(	PUNCT
cusj-7408	112	38	the	the	DET
cusj-7408	112	39	ussing	ussing	ADJ
cusj-7408	112	40	chamber	chamber	NOUN
cusj-7408	112	41	assay	assay	PROPN
cusj-7408	112	42	)	)	PUNCT
cusj-7408	112	43	and	and	CCONJ
cusj-7408	112	44	one	one	NUM
cusj-7408	112	45	measuring	measure	VERB
cusj-7408	112	46	the	the	DET
cusj-7408	112	47	concentration	concentration	NOUN
cusj-7408	112	48	of	of	ADP
cusj-7408	112	49	microbial	microbial	ADJ
cusj-7408	112	50	products	product	NOUN
cusj-7408	112	51	in	in	ADP
cusj-7408	112	52	peripheral	peripheral	ADJ
cusj-7408	112	53	blood	blood	NOUN
cusj-7408	112	54	(	(	PUNCT
cusj-7408	112	55	toll	toll	NOUN
cusj-7408	112	56	-	-	PUNCT
cusj-7408	112	57	like	like	ADJ
cusj-7408	112	58	receptor	receptor	NOUN
cusj-7408	112	59	(	(	PUNCT
cusj-7408	112	60	tlr	tlr	PROPN
cusj-7408	112	61	)	)	PUNCT
cusj-7408	112	62	assay	assay	PROPN
cusj-7408	112	63	)	)	PUNCT
cusj-7408	112	64	(	(	PUNCT
cusj-7408	112	65	figure	figure	NOUN
cusj-7408	112	66	2b	2b	NOUN
cusj-7408	112	67	,	,	PUNCT
cusj-7408	112	68	figure	figure	NOUN
cusj-7408	112	69	2c	2c	NUM
cusj-7408	112	70	)	)	PUNCT
cusj-7408	112	71	.	.	PUNCT
cusj-7408	113	1	our	our	PRON
cusj-7408	113	2	findings	finding	NOUN
cusj-7408	113	3	demonstrate	demonstrate	VERB
cusj-7408	113	4	that	that	SCONJ
cusj-7408	113	5	just	just	ADV
cusj-7408	113	6	like	like	ADP
cusj-7408	113	7	microbial	microbial	ADJ
cusj-7408	113	8	composition	composition	NOUN
cusj-7408	113	9	behaves	behave	NOUN
cusj-7408	113	10	in	in	ADP
cusj-7408	113	11	diurnal	diurnal	ADJ
cusj-7408	113	12	oscillations	oscillation	NOUN
cusj-7408	113	13	,	,	PUNCT
cusj-7408	113	14	so	so	ADV
cusj-7408	113	15	too	too	ADV
cusj-7408	113	16	does	do	VERB
cusj-7408	113	17	permeability	permeability	NOUN
cusj-7408	113	18	.	.	PUNCT
cusj-7408	114	1	from	from	ADP
cusj-7408	114	2	this	this	DET
cusj-7408	114	3	data	datum	NOUN
cusj-7408	114	4	we	we	PRON
cusj-7408	114	5	chose	choose	VERB
cusj-7408	114	6	zt2	zt2	PROPN
cusj-7408	114	7	and	and	CCONJ
cusj-7408	114	8	zt14	zt14	PROPN
cusj-7408	114	9	as	as	ADP
cusj-7408	114	10	the	the	DET
cusj-7408	114	11	lowest	low	ADJ
cusj-7408	114	12	and	and	CCONJ
cusj-7408	114	13	highest	high	ADJ
cusj-7408	114	14	points	point	NOUN
cusj-7408	114	15	of	of	ADP
cusj-7408	114	16	permeability	permeability	NOUN
cusj-7408	114	17	respectively	respectively	ADV
cusj-7408	114	18	and	and	CCONJ
cusj-7408	114	19	prepared	prepared	ADJ
cusj-7408	114	20	control	control	NOUN
cusj-7408	114	21	groups	group	NOUN
cusj-7408	114	22	at	at	ADP
cusj-7408	114	23	each	each	PRON
cusj-7408	114	24	of	of	ADP
cusj-7408	114	25	these	these	DET
cusj-7408	114	26	time	time	NOUN
cusj-7408	114	27	points	point	NOUN
cusj-7408	114	28	.	.	PUNCT
cusj-7408	115	1	this	this	PRON
cusj-7408	115	2	makes	make	VERB
cusj-7408	115	3	sense	sense	NOUN
cusj-7408	115	4	due	due	ADJ
cusj-7408	115	5	to	to	ADP
cusj-7408	115	6	the	the	DET
cusj-7408	115	7	nocturnal	nocturnal	ADJ
cusj-7408	115	8	behaviors	behavior	NOUN
cusj-7408	115	9	of	of	ADP
cusj-7408	115	10	mice	mouse	NOUN
cusj-7408	115	11	where	where	SCONJ
cusj-7408	115	12	zt2	zt2	PROPN
cusj-7408	115	13	is	be	AUX
cusj-7408	115	14	during	during	ADP
cusj-7408	115	15	the	the	DET
cusj-7408	115	16	daylight	daylight	NOUN
cusj-7408	115	17	when	when	SCONJ
cusj-7408	115	18	mice	mouse	NOUN
cusj-7408	115	19	are	be	AUX
cusj-7408	115	20	least	least	ADV
cusj-7408	115	21	active	active	ADJ
cusj-7408	115	22	while	while	SCONJ
cusj-7408	115	23	zt14	zt14	PROPN
cusj-7408	115	24	is	be	AUX
cusj-7408	115	25	during	during	ADP
cusj-7408	115	26	the	the	DET
cusj-7408	115	27	night	night	NOUN
cusj-7408	115	28	is	be	AUX
cusj-7408	115	29	when	when	SCONJ
cusj-7408	115	30	mice	mouse	NOUN
cusj-7408	115	31	are	be	AUX
cusj-7408	115	32	most	most	ADV
cusj-7408	115	33	active	active	ADJ
cusj-7408	115	34	.	.	PUNCT
cusj-7408	116	1	we	we	PRON
cusj-7408	116	2	then	then	ADV
cusj-7408	116	3	set	set	VERB
cusj-7408	116	4	out	out	ADP
cusj-7408	116	5	to	to	PART
cusj-7408	116	6	mimic	mimic	VERB
cusj-7408	116	7	the	the	DET
cusj-7408	116	8	situation	situation	NOUN
cusj-7408	116	9	of	of	ADP
cusj-7408	116	10	shift	shift	NOUN
cusj-7408	116	11	work	work	NOUN
cusj-7408	116	12	and	and	CCONJ
cusj-7408	116	13	chronic	chronic	ADJ
cusj-7408	116	14	jet	jet	NOUN
cusj-7408	116	15	lag	lag	NOUN
cusj-7408	116	16	by	by	ADP
cusj-7408	116	17	using	use	VERB
cusj-7408	116	18	a	a	DET
cusj-7408	116	19	jet	jet	NOUN
cusj-7408	116	20	lag	lag	NOUN
cusj-7408	116	21	model	model	NOUN
cusj-7408	116	22	in	in	ADP
cusj-7408	116	23	which	which	PRON
cusj-7408	116	24	mice	mouse	NOUN
cusj-7408	116	25	were	be	AUX
cusj-7408	116	26	exposed	expose	VERB
cusj-7408	116	27	to	to	ADP
cusj-7408	116	28	a	a	DET
cusj-7408	116	29	12	12	NUM
cusj-7408	116	30	-	-	PUNCT
cusj-7408	116	31	hour	hour	NOUN
cusj-7408	116	32	time	time	NOUN
cusj-7408	116	33	shift	shift	NOUN
cusj-7408	116	34	every	every	DET
cusj-7408	116	35	3	3	NUM
cusj-7408	116	36	days	day	NOUN
cusj-7408	116	37	.	.	PUNCT
cusj-7408	117	1	using	use	VERB
cusj-7408	117	2	a	a	DET
cusj-7408	117	3	circadian	circadian	ADJ
cusj-7408	117	4	cabinet	cabinet	NOUN
cusj-7408	117	5	,	,	PUNCT
cusj-7408	117	6	which	which	PRON
cusj-7408	117	7	allows	allow	VERB
cusj-7408	117	8	us	we	PRON
cusj-7408	117	9	to	to	PART
cusj-7408	117	10	individually	individually	ADV
cusj-7408	117	11	control	control	VERB
cusj-7408	117	12	the	the	DET
cusj-7408	117	13	light	light	ADJ
cusj-7408	117	14	cycles	cycle	NOUN
cusj-7408	117	15	of	of	ADP
cusj-7408	117	16	each	each	DET
cusj-7408	117	17	compartment	compartment	NOUN
cusj-7408	117	18	,	,	PUNCT
cusj-7408	117	19	a	a	DET
cusj-7408	117	20	group	group	NOUN
cusj-7408	117	21	of	of	ADP
cusj-7408	117	22	mice	mouse	NOUN
cusj-7408	117	23	were	be	AUX
cusj-7408	117	24	initially	initially	ADV
cusj-7408	117	25	started	start	VERB
cusj-7408	117	26	in	in	ADP
cusj-7408	117	27	one	one	NUM
cusj-7408	117	28	of	of	ADP
cusj-7408	117	29	two	two	NUM
cusj-7408	117	30	a	a	DET
cusj-7408	117	31	b	b	NOUN
cusj-7408	117	32	c	c	NOUN
cusj-7408	117	33	ed	ed	NOUN
cusj-7408	117	34	figure	figure	NOUN
cusj-7408	117	35	1	1	NUM
cusj-7408	117	36	.	.	PUNCT
cusj-7408	118	1	state	state	NOUN
cusj-7408	118	2	of	of	ADP
cusj-7408	118	3	small	small	ADJ
cusj-7408	118	4	intestinal	intestinal	ADJ
cusj-7408	118	5	microbiome	microbiome	NOUN
cusj-7408	118	6	determines	determine	VERB
cusj-7408	118	7	epithelial	epithelial	ADJ
cusj-7408	118	8	barrier	barrier	NOUN
cusj-7408	118	9	function	function	NOUN
cusj-7408	118	10	.	.	PUNCT
cusj-7408	119	1	(	(	PUNCT
cusj-7408	119	2	a	a	X
cusj-7408	119	3	)	)	PUNCT
cusj-7408	119	4	schematic	schematic	ADJ
cusj-7408	119	5	summarizing	summarizing	NOUN
cusj-7408	119	6	transplantation	transplantation	NOUN
cusj-7408	119	7	of	of	ADP
cusj-7408	119	8	microbiota	microbiota	NOUN
cusj-7408	119	9	from	from	ADP
cusj-7408	119	10	hfd	hfd	PROPN
cusj-7408	119	11	,	,	PUNCT
cusj-7408	119	12	nc	nc	PROPN
cusj-7408	119	13	and	and	CCONJ
cusj-7408	119	14	pbs	pbs	PROPN
cusj-7408	119	15	into	into	ADP
cusj-7408	119	16	germ	germ	NOUN
cusj-7408	119	17	-	-	PUNCT
cusj-7408	119	18	free	free	ADJ
cusj-7408	119	19	recipient	recipient	NOUN
cusj-7408	119	20	mice	mouse	NOUN
cusj-7408	119	21	.	.	PUNCT
cusj-7408	120	1	(	(	PUNCT
cusj-7408	120	2	b	b	X
cusj-7408	120	3	)	)	PUNCT
cusj-7408	120	4	ussing	usse	VERB
cusj-7408	120	5	chamber	chamber	NOUN
cusj-7408	120	6	recording	recording	NOUN
cusj-7408	120	7	of	of	ADP
cusj-7408	120	8	small	small	ADJ
cusj-7408	120	9	intestines	intestine	NOUN
cusj-7408	120	10	from	from	ADP
cusj-7408	120	11	gf	gf	PROPN
cusj-7408	120	12	mice	mouse	NOUN
cusj-7408	120	13	;	;	PUNCT
cusj-7408	120	14	measuring	measure	VERB
cusj-7408	120	15	current	current	ADJ
cusj-7408	120	16	(	(	PUNCT
cusj-7408	120	17	ma	ma	PROPN
cusj-7408	120	18	)	)	PUNCT
cusj-7408	120	19	as	as	ADP
cusj-7408	120	20	a	a	DET
cusj-7408	120	21	measurement	measurement	NOUN
cusj-7408	120	22	of	of	ADP
cusj-7408	120	23	permeability	permeability	NOUN
cusj-7408	120	24	.	.	PUNCT
cusj-7408	121	1	(	(	PUNCT
cusj-7408	121	2	c	c	X
cusj-7408	121	3	)	)	PUNCT
cusj-7408	121	4	schematic	schematic	ADJ
cusj-7408	121	5	showing	show	VERB
cusj-7408	121	6	a	a	DET
cusj-7408	121	7	murine	murine	ADJ
cusj-7408	121	8	antibiotic	antibiotic	ADJ
cusj-7408	121	9	treatment	treatment	NOUN
cusj-7408	121	10	setup	setup	NOUN
cusj-7408	121	11	.	.	PUNCT
cusj-7408	122	1	(	(	PUNCT
cusj-7408	122	2	d	d	X
cusj-7408	122	3	)	)	PUNCT
cusj-7408	122	4	fitc	fitc	NOUN
cusj-7408	122	5	(	(	PUNCT
cusj-7408	122	6	fluorescein	fluorescein	NOUN
cusj-7408	122	7	isothiocyanate)-dextran	isothiocyanate)-dextran	PROPN
cusj-7408	122	8	recovered	recover	VERB
cusj-7408	122	9	from	from	ADP
cusj-7408	122	10	the	the	DET
cusj-7408	122	11	serum	serum	NOUN
cusj-7408	122	12	of	of	ADP
cusj-7408	122	13	antibiotic	antibiotic	NOUN
cusj-7408	122	14	treated	treat	VERB
cusj-7408	122	15	wt	wt	NUM
cusj-7408	122	16	mice	mouse	NOUN
cusj-7408	122	17	and	and	CCONJ
cusj-7408	122	18	control	control	NOUN
cusj-7408	122	19	.	.	PUNCT
cusj-7408	123	1	(	(	PUNCT
cusj-7408	123	2	e	e	NOUN
cusj-7408	123	3	)	)	PUNCT
cusj-7408	123	4	ussing	usse	VERB
cusj-7408	123	5	chamber	chamber	NOUN
cusj-7408	123	6	recording	recording	NOUN
cusj-7408	123	7	of	of	ADP
cusj-7408	123	8	small	small	ADJ
cusj-7408	123	9	intestines	intestine	NOUN
cusj-7408	123	10	from	from	ADP
cusj-7408	123	11	antibiotic	antibiotic	NOUN
cusj-7408	123	12	treated	treat	VERB
cusj-7408	123	13	wt	wt	NUM
cusj-7408	123	14	mice	mouse	NOUN
cusj-7408	123	15	and	and	CCONJ
cusj-7408	123	16	control	control	NOUN
cusj-7408	123	17	.	.	PUNCT
cusj-7408	124	1	means	mean	VERB
cusj-7408	124	2	±	±	NUM
cusj-7408	124	3	sd	sd	NOUN
cusj-7408	124	4	are	be	AUX
cusj-7408	124	5	plotted	plot	VERB
cusj-7408	124	6	.	.	PUNCT
cusj-7408	125	1	*	*	PUNCT
cusj-7408	125	2	p	p	X
cusj-7408	125	3	<	<	X
cusj-7408	125	4	0.05	0.05	NUM
cusj-7408	125	5	,	,	PUNCT
cusj-7408	125	6	*	*	PUNCT
cusj-7408	125	7	*	*	PUNCT
cusj-7408	125	8	p	p	X
cusj-7408	125	9	<	<	X
cusj-7408	125	10	0.01	0.01	NUM
cusj-7408	125	11	,	,	PUNCT
cusj-7408	125	12	*	*	PUNCT
cusj-7408	125	13	*	*	PUNCT
cusj-7408	125	14	*	*	PUNCT
cusj-7408	125	15	p	p	X
cusj-7408	125	16	<	<	X
cusj-7408	125	17	0.001	0.001	NUM
cusj-7408	125	18	,	,	PUNCT
cusj-7408	125	19	*	*	PUNCT
cusj-7408	125	20	*	*	PUNCT
cusj-7408	125	21	*	*	PUNCT
cusj-7408	125	22	*	*	PUNCT
cusj-7408	125	23	p	p	X
cusj-7408	125	24	<	<	X
cusj-7408	125	25	0.0001	0.0001	NUM
cusj-7408	125	26	by	by	ADP
cusj-7408	125	27	mann	mann	PROPN
cusj-7408	125	28	-	-	PUNCT
cusj-7408	125	29	whitney	whitney	PROPN
cusj-7408	125	30	u	u	PROPN
cusj-7408	125	31	test	test	NOUN
cusj-7408	125	32	.	.	PUNCT
cusj-7408	126	1	11	11	NUM
cusj-7408	126	2	columbia	columbia	PROPN
cusj-7408	126	3	undergraduate	undergraduate	PROPN
cusj-7408	126	4	science	science	PROPN
cusj-7408	126	5	journal	journal	PROPN
cusj-7408	126	6	vol	vol	NOUN
cusj-7408	126	7	.	.	PROPN
cusj-7408	126	8	15	15	NUM
cusj-7408	126	9	,	,	PUNCT
cusj-7408	126	10	2021	2021	NUM
cusj-7408	126	11	pinker	pinker	PROPN
cusj-7408	126	12	et	et	PROPN
cusj-7408	126	13	.	.	PUNCT
cusj-7408	127	1	al	al	PROPN
cusj-7408	127	2	.	.	PUNCT
cusj-7408	127	3	compartments	compartment	NOUN
cusj-7408	127	4	(	(	PUNCT
cusj-7408	127	5	zt2	zt2	NOUN
cusj-7408	127	6	or	or	CCONJ
cusj-7408	127	7	zt14	zt14	PROPN
cusj-7408	127	8	)	)	PUNCT
cusj-7408	127	9	with	with	ADP
cusj-7408	127	10	light	light	ADJ
cusj-7408	127	11	cycle	cycle	NOUN
cusj-7408	127	12	’s	’s	PART
cusj-7408	127	13	12	12	NUM
cusj-7408	127	14	-	-	PUNCT
cusj-7408	127	15	hours	hour	NOUN
cusj-7408	127	16	apart	apart	ADV
cusj-7408	127	17	.	.	PUNCT
cusj-7408	128	1	every	every	DET
cusj-7408	128	2	3	3	NUM
cusj-7408	128	3	days	day	NOUN
cusj-7408	128	4	for	for	ADP
cusj-7408	128	5	3	3	NUM
cusj-7408	128	6	weeks	week	NOUN
cusj-7408	128	7	the	the	DET
cusj-7408	128	8	cages	cage	NOUN
cusj-7408	128	9	of	of	ADP
cusj-7408	128	10	mice	mouse	NOUN
cusj-7408	128	11	were	be	AUX
cusj-7408	128	12	switched	switch	VERB
cusj-7408	128	13	between	between	ADP
cusj-7408	128	14	the	the	DET
cusj-7408	128	15	two	two	NUM
cusj-7408	128	16	compartments	compartment	NOUN
cusj-7408	128	17	until	until	SCONJ
cusj-7408	128	18	they	they	PRON
cusj-7408	128	19	were	be	AUX
cusj-7408	128	20	“	"	PUNCT
cusj-7408	128	21	jet	jet	NOUN
cusj-7408	128	22	lagged	lag	VERB
cusj-7408	128	23	”	"	PUNCT
cusj-7408	128	24	.	.	PUNCT
cusj-7408	129	1	the	the	DET
cusj-7408	129	2	mice	mouse	NOUN
cusj-7408	129	3	were	be	AUX
cusj-7408	129	4	then	then	ADV
cusj-7408	129	5	bled	bleed	VERB
cusj-7408	129	6	for	for	ADP
cusj-7408	129	7	fitc	fitc	NOUN
cusj-7408	129	8	-	-	PUNCT
cusj-7408	129	9	dextran	dextran	VERB
cusj-7408	129	10	assay	assay	NOUN
cusj-7408	129	11	at	at	ADP
cusj-7408	129	12	the	the	DET
cusj-7408	129	13	same	same	ADJ
cusj-7408	129	14	time	time	NOUN
cusj-7408	129	15	,	,	PUNCT
cusj-7408	129	16	zt2	zt2	PROPN
cusj-7408	129	17	and	and	CCONJ
cusj-7408	129	18	zt14	zt14	PROPN
cusj-7408	129	19	,	,	PUNCT
cusj-7408	129	20	depending	depend	VERB
cusj-7408	129	21	on	on	ADP
cusj-7408	129	22	the	the	DET
cusj-7408	129	23	compartment	compartment	NOUN
cusj-7408	129	24	.	.	PUNCT
cusj-7408	130	1	however	however	ADV
cusj-7408	130	2	,	,	PUNCT
cusj-7408	130	3	if	if	SCONJ
cusj-7408	130	4	the	the	DET
cusj-7408	130	5	mice	mouse	NOUN
cusj-7408	130	6	were	be	AUX
cusj-7408	130	7	jet	jet	NOUN
cusj-7408	130	8	lagged	lag	VERB
cusj-7408	130	9	properly	properly	ADV
cusj-7408	130	10	,	,	PUNCT
cusj-7408	130	11	and	and	CCONJ
cusj-7408	130	12	their	their	PRON
cusj-7408	130	13	circadian	circadian	ADJ
cusj-7408	130	14	clock	clock	NOUN
cusj-7408	130	15	was	be	AUX
cusj-7408	130	16	disrupted	disrupt	VERB
cusj-7408	130	17	,	,	PUNCT
cusj-7408	130	18	the	the	DET
cusj-7408	130	19	zt	zt	PROPN
cusj-7408	130	20	time	time	NOUN
cusj-7408	130	21	at	at	ADP
cusj-7408	130	22	which	which	PRON
cusj-7408	130	23	blood	blood	NOUN
cusj-7408	130	24	was	be	AUX
cusj-7408	130	25	drawn	draw	VERB
cusj-7408	130	26	would	would	AUX
cusj-7408	130	27	not	not	PART
cusj-7408	130	28	matter	matter	VERB
cusj-7408	130	29	.	.	PUNCT
cusj-7408	131	1	the	the	DET
cusj-7408	131	2	results	result	NOUN
cusj-7408	131	3	showed	show	VERB
cusj-7408	131	4	that	that	SCONJ
cusj-7408	131	5	the	the	DET
cusj-7408	131	6	od	od	NOUN
cusj-7408	131	7	from	from	ADP
cusj-7408	131	8	fitc	fitc	NOUN
cusj-7408	131	9	-	-	PUNCT
cusj-7408	131	10	dextran	dextran	NOUN
cusj-7408	131	11	between	between	ADP
cusj-7408	131	12	jet	jet	NOUN
cusj-7408	131	13	lag	lag	NOUN
cusj-7408	131	14	groups	group	NOUN
cusj-7408	131	15	zt2	zt2	PROPN
cusj-7408	131	16	and	and	CCONJ
cusj-7408	131	17	zt14	zt14	PROPN
cusj-7408	131	18	were	be	AUX
cusj-7408	131	19	non	non	ADJ
cusj-7408	131	20	-	-	ADJ
cusj-7408	131	21	significant	significant	ADJ
cusj-7408	131	22	(	(	PUNCT
cusj-7408	131	23	figure	figure	NOUN
cusj-7408	131	24	2d	2d	NOUN
cusj-7408	131	25	)	)	PUNCT
cusj-7408	131	26	.	.	PUNCT
cusj-7408	132	1	additionally	additionally	ADV
cusj-7408	132	2	,	,	PUNCT
cusj-7408	132	3	compared	compare	VERB
cusj-7408	132	4	to	to	ADP
cusj-7408	132	5	the	the	DET
cusj-7408	132	6	controls	control	NOUN
cusj-7408	132	7	,	,	PUNCT
cusj-7408	132	8	the	the	DET
cusj-7408	132	9	jet	jet	NOUN
cusj-7408	132	10	lag	lag	NOUN
cusj-7408	132	11	groups	group	NOUN
cusj-7408	132	12	’	'	PUNCT
cusj-7408	132	13	ods	od	NOUN
cusj-7408	132	14	was	be	AUX
cusj-7408	132	15	closer	close	ADJ
cusj-7408	132	16	to	to	PART
cusj-7408	132	17	control	control	VERB
cusj-7408	132	18	zt14	zt14	PROPN
cusj-7408	132	19	(	(	PUNCT
cusj-7408	132	20	highest	high	ADJ
cusj-7408	132	21	measured	measure	VERB
cusj-7408	132	22	permeability	permeability	NOUN
cusj-7408	132	23	)	)	PUNCT
cusj-7408	132	24	than	than	ADP
cusj-7408	132	25	control	control	PROPN
cusj-7408	132	26	zt2	zt2	PROPN
cusj-7408	132	27	(	(	PUNCT
cusj-7408	132	28	lowest	low	ADJ
cusj-7408	132	29	measured	measure	VERB
cusj-7408	132	30	permeability	permeability	NOUN
cusj-7408	132	31	)	)	PUNCT
cusj-7408	132	32	.	.	PUNCT
cusj-7408	133	1	when	when	SCONJ
cusj-7408	133	2	we	we	PRON
cusj-7408	133	3	excised	excise	VERB
cusj-7408	133	4	small	small	ADJ
cusj-7408	133	5	intestine	intestine	NOUN
cusj-7408	133	6	samples	sample	NOUN
cusj-7408	133	7	,	,	PUNCT
cusj-7408	133	8	for	for	ADP
cusj-7408	133	9	ussing	usse	VERB
cusj-7408	133	10	chamber	chamber	NOUN
cusj-7408	133	11	assay	assay	NOUN
cusj-7408	133	12	,	,	PUNCT
cusj-7408	133	13	we	we	PRON
cusj-7408	133	14	observed	observe	VERB
cusj-7408	133	15	similar	similar	ADJ
cusj-7408	133	16	trends	trend	NOUN
cusj-7408	133	17	:	:	PUNCT
cusj-7408	133	18	non	non	ADJ
cusj-7408	133	19	-	-	ADJ
cusj-7408	133	20	significant	significant	ADJ
cusj-7408	133	21	permeability	permeability	NOUN
cusj-7408	133	22	measurements	measurement	NOUN
cusj-7408	133	23	between	between	ADP
cusj-7408	133	24	jet	jet	NOUN
cusj-7408	133	25	lag	lag	NOUN
cusj-7408	133	26	groups	group	NOUN
cusj-7408	133	27	(	(	PUNCT
cusj-7408	133	28	sign	sign	NOUN
cusj-7408	133	29	of	of	ADP
cusj-7408	133	30	successful	successful	ADJ
cusj-7408	133	31	jet	jet	NOUN
cusj-7408	133	32	lag	lag	NOUN
cusj-7408	133	33	)	)	PUNCT
cusj-7408	133	34	and	and	CCONJ
cusj-7408	133	35	overall	overall	ADJ
cusj-7408	133	36	permeability	permeability	NOUN
cusj-7408	133	37	levels	level	NOUN
cusj-7408	133	38	aligned	align	VERB
cusj-7408	133	39	with	with	ADP
cusj-7408	133	40	zt14	zt14	PROPN
cusj-7408	133	41	control	control	NOUN
cusj-7408	133	42	levels	level	NOUN
cusj-7408	133	43	(	(	PUNCT
cusj-7408	133	44	figure	figure	NOUN
cusj-7408	133	45	2e	2e	NUM
cusj-7408	133	46	)	)	PUNCT
cusj-7408	133	47	.	.	PUNCT
cusj-7408	134	1	altogether	altogether	ADV
cusj-7408	134	2	,	,	PUNCT
cusj-7408	134	3	these	these	DET
cusj-7408	134	4	data	datum	NOUN
cusj-7408	134	5	suggest	suggest	VERB
cusj-7408	134	6	that	that	SCONJ
cusj-7408	134	7	chronic	chronic	ADJ
cusj-7408	134	8	environmental	environmental	ADJ
cusj-7408	134	9	(	(	PUNCT
cusj-7408	134	10	jet	jet	NOUN
cusj-7408	134	11	lag	lag	NOUN
cusj-7408	134	12	model	model	NOUN
cusj-7408	134	13	)	)	PUNCT
cusj-7408	134	14	or	or	CCONJ
cusj-7408	134	15	genetic	genetic	ADJ
cusj-7408	134	16	disruption	disruption	NOUN
cusj-7408	134	17	(	(	PUNCT
cusj-7408	134	18	per1/2-/-	per1/2-/-	NOUN
cusj-7408	134	19	)	)	PUNCT
cusj-7408	134	20	of	of	ADP
cusj-7408	134	21	host	host	NOUN
cusj-7408	134	22	light	light	ADJ
cusj-7408	134	23	-	-	PUNCT
cusj-7408	134	24	dark	dark	NOUN
cusj-7408	134	25	cycles	cycle	NOUN
cusj-7408	134	26	exhibits	exhibit	VERB
cusj-7408	134	27	significant	significant	ADJ
cusj-7408	134	28	alterations	alteration	NOUN
cusj-7408	134	29	in	in	ADP
cusj-7408	134	30	intestinal	intestinal	ADJ
cusj-7408	134	31	epithelial	epithelial	ADJ
cusj-7408	134	32	barrier	barrier	NOUN
cusj-7408	134	33	function	function	NOUN
cusj-7408	134	34	and	and	CCONJ
cusj-7408	134	35	as	as	ADP
cusj-7408	134	36	a	a	DET
cusj-7408	134	37	result	result	NOUN
cusj-7408	134	38	increasing	increase	VERB
cusj-7408	134	39	barrier	barrier	NOUN
cusj-7408	134	40	permeability	permeability	NOUN
cusj-7408	134	41	.	.	PUNCT
cusj-7408	135	1	this	this	PRON
cusj-7408	135	2	has	have	VERB
cusj-7408	135	3	relevance	relevance	NOUN
cusj-7408	135	4	for	for	ADP
cusj-7408	135	5	frequent	frequent	ADJ
cusj-7408	135	6	fliers	flier	NOUN
cusj-7408	135	7	traveling	travel	VERB
cusj-7408	135	8	across	across	ADP
cusj-7408	135	9	different	different	ADJ
cusj-7408	135	10	time	time	NOUN
cusj-7408	135	11	zones	zone	NOUN
cusj-7408	135	12	and	and	CCONJ
cusj-7408	135	13	people	people	NOUN
cusj-7408	135	14	who	who	PRON
cusj-7408	135	15	perform	perform	VERB
cusj-7408	135	16	shift	shift	NOUN
cusj-7408	135	17	work	work	NOUN
cusj-7408	135	18	.	.	PUNCT
cusj-7408	136	1	additionally	additionally	ADV
cusj-7408	136	2	,	,	PUNCT
cusj-7408	136	3	our	our	PRON
cusj-7408	136	4	data	datum	NOUN
cusj-7408	136	5	suggests	suggest	VERB
cusj-7408	136	6	an	an	DET
cusj-7408	136	7	explanation	explanation	NOUN
cusj-7408	136	8	for	for	ADP
cusj-7408	136	9	clinical	clinical	ADJ
cusj-7408	136	10	observations	observation	NOUN
cusj-7408	136	11	,	,	PUNCT
cusj-7408	136	12	finding	find	VERB
cusj-7408	136	13	shift	shift	NOUN
cusj-7408	136	14	workers	worker	NOUN
cusj-7408	136	15	,	,	PUNCT
cusj-7408	136	16	with	with	ADP
cusj-7408	136	17	irregular	irregular	ADJ
cusj-7408	136	18	sleep	sleep	NOUN
cusj-7408	136	19	/	/	SYM
cusj-7408	136	20	wake	wake	VERB
cusj-7408	136	21	schedules	schedule	NOUN
cusj-7408	136	22	,	,	PUNCT
cusj-7408	136	23	to	to	PART
cusj-7408	136	24	experience	experience	NOUN
cusj-7408	136	25	exacerbated	exacerbate	VERB
cusj-7408	136	26	inflammatory	inflammatory	ADJ
cusj-7408	136	27	bowel	bowel	NOUN
cusj-7408	136	28	disease	disease	NOUN
cusj-7408	136	29	(	(	PUNCT
cusj-7408	136	30	ibd	ibd	PROPN
cusj-7408	136	31	)	)	PUNCT
cusj-7408	136	32	due	due	ADP
cusj-7408	136	33	to	to	ADP
cusj-7408	136	34	the	the	DET
cusj-7408	136	35	effect	effect	NOUN
cusj-7408	136	36	endogenous	endogenous	ADJ
cusj-7408	136	37	misalignment	misalignment	NOUN
cusj-7408	136	38	of	of	ADP
cusj-7408	136	39	circadian	circadian	ADJ
cusj-7408	136	40	rhythms	rhythm	NOUN
cusj-7408	136	41	has	have	VERB
cusj-7408	136	42	on	on	ADP
cusj-7408	136	43	intestinal	intestinal	ADJ
cusj-7408	136	44	homeostasis	homeostasis	NOUN
cusj-7408	136	45	‎[26	‎[26	ADJ
cusj-7408	136	46	]	]	PUNCT
cusj-7408	136	47	.	.	PUNCT
cusj-7408	137	1	metabolic	metabolic	PROPN
cusj-7408	137	2	syndrome	syndrome	NOUN
cusj-7408	137	3	induced	induce	VERB
cusj-7408	137	4	by	by	ADP
cusj-7408	137	5	hfd	hfd	PROPN
cusj-7408	137	6	results	result	NOUN
cusj-7408	137	7	in	in	ADP
cusj-7408	137	8	circadian	circadian	ADJ
cusj-7408	137	9	disruption	disruption	NOUN
cusj-7408	137	10	and	and	CCONJ
cusj-7408	137	11	intestinal	intestinal	ADJ
cusj-7408	137	12	barrier	barrier	NOUN
cusj-7408	137	13	dysfunction	dysfunction	NOUN
cusj-7408	137	14	metabolic	metabolic	NOUN
cusj-7408	137	15	syndromes	syndrome	NOUN
cusj-7408	137	16	,	,	PUNCT
cusj-7408	137	17	like	like	ADP
cusj-7408	137	18	obesity	obesity	NOUN
cusj-7408	137	19	and	and	CCONJ
cusj-7408	137	20	diabetes	diabetes	NOUN
cusj-7408	137	21	,	,	PUNCT
cusj-7408	137	22	have	have	AUX
cusj-7408	137	23	impacted	impact	VERB
cusj-7408	137	24	hundreds	hundred	NOUN
cusj-7408	137	25	of	of	ADP
cusj-7408	137	26	millions	million	NOUN
cusj-7408	137	27	of	of	ADP
cusj-7408	137	28	people	people	NOUN
cusj-7408	137	29	worldwide	worldwide	ADV
cusj-7408	137	30	and	and	CCONJ
cusj-7408	137	31	consequently	consequently	ADV
cusj-7408	137	32	taken	take	VERB
cusj-7408	137	33	the	the	DET
cusj-7408	137	34	lives	life	NOUN
cusj-7408	137	35	of	of	ADP
cusj-7408	137	36	millions	million	NOUN
cusj-7408	137	37	annually	annually	ADV
cusj-7408	137	38	‎[25	‎[25	NOUN
cusj-7408	137	39	]	]	PUNCT
cusj-7408	137	40	.	.	PUNCT
cusj-7408	138	1	previous	previous	ADJ
cusj-7408	138	2	studies	study	NOUN
cusj-7408	138	3	have	have	AUX
cusj-7408	138	4	uncovered	uncover	VERB
cusj-7408	138	5	the	the	DET
cusj-7408	138	6	associations	association	NOUN
cusj-7408	138	7	metabolic	metabolic	NOUN
cusj-7408	138	8	syndromes	syndrome	NOUN
cusj-7408	138	9	have	have	VERB
cusj-7408	138	10	with	with	ADP
cusj-7408	138	11	the	the	DET
cusj-7408	138	12	functionality	functionality	NOUN
cusj-7408	138	13	of	of	ADP
cusj-7408	138	14	the	the	DET
cusj-7408	138	15	intesfigure	intesfigure	NOUN
cusj-7408	139	1	2	2	NUM
cusj-7408	139	2	.	.	PUNCT
cusj-7408	139	3	genetic	genetic	ADJ
cusj-7408	139	4	and	and	CCONJ
cusj-7408	139	5	environmental	environmental	ADJ
cusj-7408	139	6	disruption	disruption	NOUN
cusj-7408	139	7	of	of	ADP
cusj-7408	139	8	circadian	circadian	ADJ
cusj-7408	139	9	clocks	clock	NOUN
cusj-7408	139	10	impacts	impact	VERB
cusj-7408	139	11	epithelial	epithelial	ADJ
cusj-7408	139	12	barrier	barrier	NOUN
cusj-7408	139	13	integrity	integrity	NOUN
cusj-7408	139	14	.	.	PUNCT
cusj-7408	140	1	(	(	PUNCT
cusj-7408	140	2	a	a	X
cusj-7408	140	3	)	)	PUNCT
cusj-7408	140	4	fitc	fitc	NOUN
cusj-7408	140	5	(	(	PUNCT
cusj-7408	140	6	fluorescein	fluorescein	NOUN
cusj-7408	140	7	isothiocyanate)-dextran	isothiocyanate)-dextran	PROPN
cusj-7408	140	8	recovered	recover	VERB
cusj-7408	140	9	from	from	ADP
cusj-7408	140	10	the	the	DET
cusj-7408	140	11	serum	serum	NOUN
cusj-7408	140	12	of	of	ADP
cusj-7408	140	13	per1/2-/and	per1/2-/and	PROPN
cusj-7408	140	14	wt	wt	PROPN
cusj-7408	140	15	.	.	PUNCT
cusj-7408	140	16	(	(	PUNCT
cusj-7408	140	17	b	b	NOUN
cusj-7408	140	18	)	)	PUNCT
cusj-7408	140	19	ussing	usse	VERB
cusj-7408	140	20	chamber	chamber	NOUN
cusj-7408	140	21	recording	recording	NOUN
cusj-7408	140	22	of	of	ADP
cusj-7408	140	23	small	small	ADJ
cusj-7408	140	24	intestines	intestine	NOUN
cusj-7408	140	25	from	from	ADP
cusj-7408	140	26	naïve	naïve	ADJ
cusj-7408	140	27	wt	wt	NOUN
cusj-7408	140	28	over	over	ADP
cusj-7408	140	29	24	24	NUM
cusj-7408	140	30	hours	hour	NOUN
cusj-7408	140	31	.	.	PUNCT
cusj-7408	141	1	arrows	arrow	NOUN
cusj-7408	141	2	mark	mark	VERB
cusj-7408	141	3	the	the	DET
cusj-7408	141	4	lowest	low	ADJ
cusj-7408	141	5	(	(	PUNCT
cusj-7408	141	6	zt2	zt2	NOUN
cusj-7408	141	7	)	)	PUNCT
cusj-7408	141	8	and	and	CCONJ
cusj-7408	141	9	highest	high	ADJ
cusj-7408	141	10	(	(	PUNCT
cusj-7408	141	11	zt14	zt14	PROPN
cusj-7408	141	12	)	)	PUNCT
cusj-7408	141	13	points	point	NOUN
cusj-7408	141	14	of	of	ADP
cusj-7408	141	15	permeability	permeability	NOUN
cusj-7408	141	16	.	.	PUNCT
cusj-7408	142	1	(	(	PUNCT
cusj-7408	142	2	c	c	X
cusj-7408	142	3	)	)	PUNCT
cusj-7408	142	4	prr	prr	NOUN
cusj-7408	142	5	stimulation	stimulation	NOUN
cusj-7408	142	6	by	by	ADP
cusj-7408	142	7	spleen	spleen	PROPN
cusj-7408	142	8	,	,	PUNCT
cusj-7408	142	9	liver	liver	NOUN
cusj-7408	142	10	,	,	PUNCT
cusj-7408	142	11	serum	serum	NOUN
cusj-7408	142	12	extracts	extract	NOUN
cusj-7408	142	13	from	from	ADP
cusj-7408	142	14	naïve	naïve	ADJ
cusj-7408	142	15	wt	wt	NOUN
cusj-7408	142	16	mice	mouse	NOUN
cusj-7408	142	17	.	.	PUNCT
cusj-7408	143	1	arrows	arrow	NOUN
cusj-7408	143	2	mark	mark	VERB
cusj-7408	143	3	the	the	DET
cusj-7408	143	4	lowest	low	ADJ
cusj-7408	143	5	(	(	PUNCT
cusj-7408	143	6	zt2	zt2	NOUN
cusj-7408	143	7	)	)	PUNCT
cusj-7408	143	8	and	and	CCONJ
cusj-7408	143	9	highest	high	ADJ
cusj-7408	143	10	(	(	PUNCT
cusj-7408	143	11	zt14	zt14	PROPN
cusj-7408	143	12	)	)	PUNCT
cusj-7408	143	13	points	point	NOUN
cusj-7408	143	14	of	of	ADP
cusj-7408	143	15	permeability	permeability	NOUN
cusj-7408	143	16	.	.	PUNCT
cusj-7408	144	1	(	(	PUNCT
cusj-7408	144	2	d	d	X
cusj-7408	144	3	)	)	PUNCT
cusj-7408	144	4	fitc	fitc	NOUN
cusj-7408	144	5	(	(	PUNCT
cusj-7408	144	6	fluorescein	fluorescein	NOUN
cusj-7408	144	7	isothiocyanate)-dextran	isothiocyanate)-dextran	PROPN
cusj-7408	144	8	recovered	recover	VERB
cusj-7408	144	9	from	from	ADP
cusj-7408	144	10	the	the	DET
cusj-7408	144	11	serum	serum	NOUN
cusj-7408	144	12	of	of	ADP
cusj-7408	144	13	jet	jet	NOUN
cusj-7408	144	14	lag	lag	NOUN
cusj-7408	144	15	mice	mouse	NOUN
cusj-7408	144	16	and	and	CCONJ
cusj-7408	144	17	their	their	PRON
cusj-7408	144	18	respective	respective	ADJ
cusj-7408	144	19	controls	control	NOUN
cusj-7408	144	20	.	.	PUNCT
cusj-7408	145	1	(	(	PUNCT
cusj-7408	145	2	e	e	NOUN
cusj-7408	145	3	)	)	PUNCT
cusj-7408	145	4	ussing	usse	VERB
cusj-7408	145	5	chamber	chamber	NOUN
cusj-7408	145	6	recording	recording	NOUN
cusj-7408	145	7	of	of	ADP
cusj-7408	145	8	small	small	ADJ
cusj-7408	145	9	intestines	intestine	NOUN
cusj-7408	145	10	from	from	ADP
cusj-7408	145	11	jet	jet	NOUN
cusj-7408	145	12	lag	lag	NOUN
cusj-7408	145	13	mice	mouse	NOUN
cusj-7408	145	14	and	and	CCONJ
cusj-7408	145	15	their	their	PRON
cusj-7408	145	16	respective	respective	ADJ
cusj-7408	145	17	controls	control	NOUN
cusj-7408	145	18	.	.	PUNCT
cusj-7408	146	1	means	mean	VERB
cusj-7408	146	2	±	±	NUM
cusj-7408	146	3	sd	sd	NOUN
cusj-7408	146	4	are	be	AUX
cusj-7408	146	5	plotted	plot	VERB
cusj-7408	146	6	.	.	PUNCT
cusj-7408	147	1	*	*	PUNCT
cusj-7408	147	2	p	p	X
cusj-7408	147	3	<	<	X
cusj-7408	147	4	0.05	0.05	NUM
cusj-7408	147	5	,	,	PUNCT
cusj-7408	147	6	*	*	PUNCT
cusj-7408	147	7	*	*	PUNCT
cusj-7408	147	8	p	p	X
cusj-7408	147	9	<	<	X
cusj-7408	147	10	0.01	0.01	NUM
cusj-7408	147	11	,	,	PUNCT
cusj-7408	147	12	*	*	PUNCT
cusj-7408	147	13	*	*	PUNCT
cusj-7408	147	14	*	*	PUNCT
cusj-7408	147	15	p	p	X
cusj-7408	147	16	<	<	X
cusj-7408	147	17	0.001	0.001	NUM
cusj-7408	147	18	,	,	PUNCT
cusj-7408	147	19	*	*	PUNCT
cusj-7408	147	20	*	*	PUNCT
cusj-7408	147	21	*	*	PUNCT
cusj-7408	147	22	*	*	PUNCT
cusj-7408	147	23	p	p	X
cusj-7408	147	24	<	<	X
cusj-7408	147	25	0.0001	0.0001	NUM
cusj-7408	147	26	by	by	ADP
cusj-7408	147	27	mann	mann	PROPN
cusj-7408	147	28	-	-	PUNCT
cusj-7408	147	29	whitney	whitney	PROPN
cusj-7408	147	30	u	u	PROPN
cusj-7408	147	31	test	test	NOUN
cusj-7408	147	32	.	.	PUNCT
cusj-7408	148	1	figures	figure	VERB
cusj-7408	148	2	2d	2d	NOUN
cusj-7408	148	3	and	and	CCONJ
cusj-7408	148	4	2e	2e	NUM
cusj-7408	148	5	:	:	PUNCT
cusj-7408	148	6	2	2	NUM
cusj-7408	148	7	-	-	PUNCT
cusj-7408	148	8	way	way	NOUN
cusj-7408	148	9	anova	anova	PROPN
cusj-7408	148	10	test	test	NOUN
cusj-7408	148	11	.	.	PUNCT
cusj-7408	149	1	a	a	DET
cusj-7408	149	2	b	b	X
cusj-7408	149	3	c	c	NOUN
cusj-7408	149	4	d	d	PROPN
cusj-7408	149	5	e	e	PROPN
cusj-7408	149	6	12	12	NUM
cusj-7408	149	7	columbia	columbia	PROPN
cusj-7408	149	8	undergraduate	undergraduate	PROPN
cusj-7408	149	9	science	science	PROPN
cusj-7408	149	10	journal	journal	PROPN
cusj-7408	149	11	vol	vol	NOUN
cusj-7408	149	12	.	.	PROPN
cusj-7408	149	13	15	15	NUM
cusj-7408	149	14	,	,	PUNCT
cusj-7408	149	15	2021	2021	NUM
cusj-7408	149	16	pinker	pinker	PROPN
cusj-7408	149	17	et	et	PROPN
cusj-7408	149	18	.	.	PUNCT
cusj-7408	150	1	al	al	PROPN
cusj-7408	150	2	.	.	PUNCT
cusj-7408	150	3	tinal	tinal	ADJ
cusj-7408	150	4	barrier	barrier	NOUN
cusj-7408	150	5	,	,	PUNCT
cusj-7408	150	6	specifically	specifically	ADV
cusj-7408	150	7	its	its	PRON
cusj-7408	150	8	state	state	NOUN
cusj-7408	150	9	of	of	ADP
cusj-7408	150	10	permeability	permeability	NOUN
cusj-7408	150	11	[	[	X
cusj-7408	150	12	27	27	NUM
cusj-7408	150	13	]	]	PUNCT
cusj-7408	150	14	.	.	PUNCT
cusj-7408	151	1	the	the	DET
cusj-7408	151	2	study	study	NOUN
cusj-7408	151	3	highlights	highlight	VERB
cusj-7408	151	4	the	the	DET
cusj-7408	151	5	implications	implication	NOUN
cusj-7408	151	6	an	an	DET
cusj-7408	151	7	influx	influx	NOUN
cusj-7408	151	8	of	of	ADP
cusj-7408	151	9	immune	immune	NOUN
cusj-7408	151	10	-	-	PUNCT
cusj-7408	151	11	stimulatory	stimulatory	ADJ
cusj-7408	151	12	microbial	microbial	ADJ
cusj-7408	151	13	ligands	ligand	NOUN
cusj-7408	151	14	,	,	PUNCT
cusj-7408	151	15	leaking	leak	VERB
cusj-7408	151	16	out	out	ADP
cusj-7408	151	17	of	of	ADP
cusj-7408	151	18	a	a	DET
cusj-7408	151	19	permeable	permeable	ADJ
cusj-7408	151	20	intestinal	intestinal	ADJ
cusj-7408	151	21	barrier	barrier	NOUN
cusj-7408	151	22	can	can	AUX
cusj-7408	151	23	have	have	VERB
cusj-7408	151	24	,	,	PUNCT
cusj-7408	151	25	such	such	ADJ
cusj-7408	151	26	as	as	ADP
cusj-7408	151	27	increased	increase	VERB
cusj-7408	151	28	inflammation	inflammation	NOUN
cusj-7408	151	29	and	and	CCONJ
cusj-7408	151	30	risk	risk	NOUN
cusj-7408	151	31	of	of	ADP
cusj-7408	151	32	infection	infection	NOUN
cusj-7408	151	33	[	[	X
cusj-7408	151	34	27	27	NUM
cusj-7408	151	35	]	]	PUNCT
cusj-7408	151	36	.	.	PUNCT
cusj-7408	152	1	however	however	ADV
cusj-7408	152	2	,	,	PUNCT
cusj-7408	152	3	the	the	DET
cusj-7408	152	4	tissue	tissue	NOUN
cusj-7408	152	5	under	under	ADP
cusj-7408	152	6	scrutiny	scrutiny	NOUN
cusj-7408	152	7	was	be	AUX
cusj-7408	152	8	the	the	DET
cusj-7408	152	9	colon	colon	NOUN
cusj-7408	152	10	.	.	PUNCT
cusj-7408	153	1	in	in	ADP
cusj-7408	153	2	our	our	PRON
cusj-7408	153	3	studies	study	NOUN
cusj-7408	153	4	,	,	PUNCT
cusj-7408	153	5	we	we	PRON
cusj-7408	153	6	focused	focus	VERB
cusj-7408	153	7	our	our	PRON
cusj-7408	153	8	attention	attention	NOUN
cusj-7408	153	9	on	on	ADP
cusj-7408	153	10	the	the	DET
cusj-7408	153	11	small	small	ADJ
cusj-7408	153	12	intestine	intestine	NOUN
cusj-7408	153	13	,	,	PUNCT
cusj-7408	153	14	which	which	DET
cusj-7408	153	15	one	one	PRON
cusj-7408	153	16	could	could	AUX
cusj-7408	153	17	argue	argue	VERB
cusj-7408	153	18	is	be	AUX
cusj-7408	153	19	of	of	ADP
cusj-7408	153	20	more	more	ADJ
cusj-7408	153	21	significance	significance	NOUN
cusj-7408	153	22	due	due	ADP
cusj-7408	153	23	to	to	ADP
cusj-7408	153	24	it	it	PRON
cusj-7408	153	25	being	be	AUX
cusj-7408	153	26	the	the	DET
cusj-7408	153	27	primary	primary	ADJ
cusj-7408	153	28	site	site	NOUN
cusj-7408	153	29	of	of	ADP
cusj-7408	153	30	nutrient	nutrient	ADJ
cusj-7408	153	31	absorption	absorption	NOUN
cusj-7408	153	32	[	[	X
cusj-7408	153	33	21	21	NUM
cusj-7408	153	34	]	]	PUNCT
cusj-7408	153	35	.	.	PUNCT
cusj-7408	154	1	in	in	ADP
cusj-7408	154	2	order	order	NOUN
cusj-7408	154	3	to	to	PART
cusj-7408	154	4	mimic	mimic	VERB
cusj-7408	154	5	human	human	ADJ
cusj-7408	154	6	dietary	dietary	ADJ
cusj-7408	154	7	habits	habit	NOUN
cusj-7408	154	8	,	,	PUNCT
cusj-7408	154	9	which	which	PRON
cusj-7408	154	10	would	would	AUX
cusj-7408	154	11	predispose	predispose	VERB
cusj-7408	154	12	one	one	NUM
cusj-7408	154	13	to	to	ADP
cusj-7408	154	14	a	a	DET
cusj-7408	154	15	metabolic	metabolic	NOUN
cusj-7408	154	16	syndrome	syndrome	NOUN
cusj-7408	154	17	,	,	PUNCT
cusj-7408	154	18	we	we	PRON
cusj-7408	154	19	fed	feed	VERB
cusj-7408	154	20	mice	mouse	NOUN
cusj-7408	154	21	with	with	ADP
cusj-7408	154	22	an	an	DET
cusj-7408	154	23	hfd	hfd	NOUN
cusj-7408	154	24	for	for	ADP
cusj-7408	154	25	3	3	NUM
cusj-7408	154	26	weeks	week	NOUN
cusj-7408	154	27	.	.	PUNCT
cusj-7408	155	1	in	in	ADP
cusj-7408	155	2	a	a	DET
cusj-7408	155	3	previously	previously	ADV
cusj-7408	155	4	referenced	reference	VERB
cusj-7408	155	5	chart	chart	NOUN
cusj-7408	155	6	(	(	PUNCT
cusj-7408	155	7	figure	figure	NOUN
cusj-7408	155	8	1b	1b	NUM
cusj-7408	155	9	)	)	PUNCT
cusj-7408	155	10	,	,	PUNCT
cusj-7408	155	11	where	where	SCONJ
cusj-7408	155	12	germ	germ	NOUN
cusj-7408	155	13	-	-	PUNCT
cusj-7408	155	14	free	free	ADJ
cusj-7408	155	15	mice	mouse	NOUN
cusj-7408	155	16	received	receive	VERB
cusj-7408	155	17	fecal	fecal	ADJ
cusj-7408	155	18	transplantation	transplantation	NOUN
cusj-7408	155	19	of	of	ADP
cusj-7408	155	20	an	an	DET
cusj-7408	155	21	hfd	hfd	PROPN
cusj-7408	155	22	microbiome	microbiome	NOUN
cusj-7408	155	23	we	we	PRON
cusj-7408	155	24	saw	see	VERB
cusj-7408	155	25	a	a	DET
cusj-7408	155	26	significant	significant	ADJ
cusj-7408	155	27	increase	increase	NOUN
cusj-7408	155	28	in	in	ADP
cusj-7408	155	29	small	small	ADJ
cusj-7408	155	30	intestine	intestine	NOUN
cusj-7408	155	31	permeability	permeability	NOUN
cusj-7408	155	32	than	than	ADP
cusj-7408	155	33	mice	mouse	NOUN
cusj-7408	155	34	with	with	ADP
cusj-7408	155	35	a	a	DET
cusj-7408	155	36	normal	normal	ADJ
cusj-7408	155	37	diet	diet	NOUN
cusj-7408	155	38	(	(	PUNCT
cusj-7408	155	39	nc	nc	PROPN
cusj-7408	155	40	)	)	PUNCT
cusj-7408	155	41	microbiome	microbiome	NOUN
cusj-7408	155	42	,	,	PUNCT
cusj-7408	155	43	suggesting	suggest	VERB
cusj-7408	155	44	that	that	SCONJ
cusj-7408	155	45	a	a	DET
cusj-7408	155	46	microbial	microbial	ADJ
cusj-7408	155	47	composition	composition	NOUN
cusj-7408	155	48	associated	associate	VERB
cusj-7408	155	49	with	with	ADP
cusj-7408	155	50	an	an	DET
cusj-7408	155	51	hfd	hfd	PROPN
cusj-7408	155	52	diet	diet	PROPN
cusj-7408	155	53	causes	cause	VERB
cusj-7408	155	54	intestinal	intestinal	ADJ
cusj-7408	155	55	barrier	barrier	NOUN
cusj-7408	155	56	dysfunction	dysfunction	NOUN
cusj-7408	155	57	.	.	PUNCT
cusj-7408	156	1	previous	previous	ADJ
cusj-7408	156	2	studies	study	NOUN
cusj-7408	156	3	linked	link	VERB
cusj-7408	156	4	circadian	circadian	ADJ
cusj-7408	156	5	rhythm	rhythm	NOUN
cusj-7408	156	6	disruption	disruption	NOUN
cusj-7408	156	7	to	to	ADP
cusj-7408	156	8	metabolic	metabolic	NOUN
cusj-7408	156	9	syndrome	syndrome	NOUN
cusj-7408	156	10	when	when	SCONJ
cusj-7408	156	11	they	they	PRON
cusj-7408	156	12	found	find	VERB
cusj-7408	156	13	enhanced	enhanced	ADJ
cusj-7408	156	14	weight	weight	NOUN
cusj-7408	156	15	gain	gain	NOUN
cusj-7408	156	16	and	and	CCONJ
cusj-7408	156	17	exacerbated	exacerbate	VERB
cusj-7408	156	18	glucose	glucose	NOUN
cusj-7408	156	19	intolerance	intolerance	NOUN
cusj-7408	156	20	in	in	ADP
cusj-7408	156	21	jet	jet	NOUN
cusj-7408	156	22	lag	lag	NOUN
cusj-7408	156	23	mice	mouse	NOUN
cusj-7408	156	24	fed	feed	VERB
cusj-7408	156	25	hfd	hfd	PROPN
cusj-7408	157	1	[	[	X
cusj-7408	157	2	8	8	NUM
cusj-7408	157	3	]	]	PUNCT
cusj-7408	157	4	.	.	PUNCT
cusj-7408	158	1	in	in	ADP
cusj-7408	158	2	an	an	DET
cusj-7408	158	3	attempt	attempt	NOUN
cusj-7408	158	4	to	to	PART
cusj-7408	158	5	determine	determine	VERB
cusj-7408	158	6	if	if	SCONJ
cusj-7408	158	7	an	an	DET
cusj-7408	158	8	hfd	hfd	PROPN
cusj-7408	158	9	would	would	AUX
cusj-7408	158	10	alter	alter	VERB
cusj-7408	158	11	permeability	permeability	NOUN
cusj-7408	158	12	in	in	ADP
cusj-7408	158	13	a	a	DET
cusj-7408	158	14	circadian	circadian	ADJ
cusj-7408	158	15	context	context	NOUN
cusj-7408	158	16	we	we	PRON
cusj-7408	158	17	set	set	VERB
cusj-7408	158	18	out	out	ADP
cusj-7408	158	19	to	to	PART
cusj-7408	158	20	perform	perform	VERB
cusj-7408	158	21	another	another	DET
cusj-7408	158	22	permeability	permeability	NOUN
cusj-7408	158	23	experiment	experiment	NOUN
cusj-7408	158	24	on	on	ADP
cusj-7408	158	25	hfd	hfd	PROPN
cusj-7408	158	26	mice	mouse	NOUN
cusj-7408	158	27	but	but	CCONJ
cusj-7408	158	28	under	under	ADP
cusj-7408	158	29	circadian	circadian	ADJ
cusj-7408	158	30	conditions	condition	NOUN
cusj-7408	158	31	.	.	PUNCT
cusj-7408	159	1	we	we	PRON
cusj-7408	159	2	fed	feed	VERB
cusj-7408	159	3	two	two	NUM
cusj-7408	159	4	groups	group	NOUN
cusj-7408	159	5	of	of	ADP
cusj-7408	159	6	mice	mouse	NOUN
cusj-7408	159	7	with	with	ADP
cusj-7408	159	8	hfd	hfd	PROPN
cusj-7408	159	9	for	for	ADP
cusj-7408	159	10	3	3	NUM
cusj-7408	159	11	weeks	week	NOUN
cusj-7408	159	12	.	.	PUNCT
cusj-7408	160	1	utilizing	utilize	VERB
cusj-7408	160	2	the	the	DET
cusj-7408	160	3	circadian	circadian	ADJ
cusj-7408	160	4	cabinet	cabinet	NOUN
cusj-7408	160	5	,	,	PUNCT
cusj-7408	160	6	each	each	DET
cusj-7408	160	7	group	group	NOUN
cusj-7408	160	8	was	be	AUX
cusj-7408	160	9	placed	place	VERB
cusj-7408	160	10	in	in	ADP
cusj-7408	160	11	different	different	ADJ
cusj-7408	160	12	compartments	compartment	NOUN
cusj-7408	160	13	and	and	CCONJ
cusj-7408	160	14	light	light	ADJ
cusj-7408	160	15	-	-	PUNCT
cusj-7408	160	16	dark	dark	NOUN
cusj-7408	160	17	cycles	cycle	NOUN
cusj-7408	160	18	were	be	AUX
cusj-7408	160	19	set	set	VERB
cusj-7408	160	20	12	12	NUM
cusj-7408	160	21	-	-	PUNCT
cusj-7408	160	22	hours	hour	NOUN
cusj-7408	160	23	apart	apart	ADV
cusj-7408	160	24	at	at	ADP
cusj-7408	160	25	the	the	DET
cusj-7408	160	26	previously	previously	ADV
cusj-7408	160	27	observed	observe	VERB
cusj-7408	160	28	lowest	low	ADJ
cusj-7408	160	29	and	and	CCONJ
cusj-7408	160	30	highest	high	ADJ
cusj-7408	160	31	times	time	NOUN
cusj-7408	160	32	of	of	ADP
cusj-7408	160	33	permeability	permeability	NOUN
cusj-7408	160	34	,	,	PUNCT
cusj-7408	160	35	zt2	zt2	PROPN
cusj-7408	160	36	and	and	CCONJ
cusj-7408	160	37	zt14	zt14	PROPN
cusj-7408	160	38	respectively	respectively	ADV
cusj-7408	160	39	(	(	PUNCT
cusj-7408	160	40	figure	figure	NOUN
cusj-7408	160	41	3a	3a	NUM
cusj-7408	160	42	)	)	PUNCT
cusj-7408	160	43	.	.	PUNCT
cusj-7408	161	1	fitc	fitc	NOUN
cusj-7408	161	2	-	-	PUNCT
cusj-7408	161	3	dextran	dextran	VERB
cusj-7408	161	4	assay	assay	NOUN
cusj-7408	161	5	was	be	AUX
cusj-7408	161	6	run	run	VERB
cusj-7408	161	7	and	and	CCONJ
cusj-7408	161	8	blood	blood	NOUN
cusj-7408	161	9	was	be	AUX
cusj-7408	161	10	drawn	draw	VERB
cusj-7408	161	11	at	at	ADP
cusj-7408	161	12	zt2	zt2	PROPN
cusj-7408	161	13	and	and	CCONJ
cusj-7408	161	14	zt14	zt14	PROPN
cusj-7408	161	15	depending	depend	VERB
cusj-7408	161	16	on	on	ADP
cusj-7408	161	17	which	which	PRON
cusj-7408	161	18	compartment	compartment	NOUN
cusj-7408	161	19	the	the	DET
cusj-7408	161	20	mice	mouse	NOUN
cusj-7408	161	21	were	be	AUX
cusj-7408	161	22	in	in	ADP
cusj-7408	161	23	.	.	PUNCT
cusj-7408	162	1	from	from	ADP
cusj-7408	162	2	the	the	DET
cusj-7408	162	3	fitc	fitc	NOUN
cusj-7408	162	4	-	-	PUNCT
cusj-7408	162	5	dextran	dextran	VERB
cusj-7408	162	6	data	datum	NOUN
cusj-7408	162	7	we	we	PRON
cusj-7408	162	8	see	see	VERB
cusj-7408	162	9	no	no	DET
cusj-7408	162	10	significant	significant	ADJ
cusj-7408	162	11	difference	difference	NOUN
cusj-7408	162	12	in	in	ADP
cusj-7408	162	13	od	od	NUM
cusj-7408	162	14	between	between	ADP
cusj-7408	162	15	hfd	hfd	PROPN
cusj-7408	162	16	diet	diet	PROPN
cusj-7408	162	17	groups	group	NOUN
cusj-7408	162	18	which	which	PRON
cusj-7408	162	19	suggests	suggest	VERB
cusj-7408	162	20	that	that	SCONJ
cusj-7408	162	21	the	the	DET
cusj-7408	162	22	altered	alter	VERB
cusj-7408	162	23	diet	diet	NOUN
cusj-7408	162	24	disrupted	disrupt	VERB
cusj-7408	162	25	circadian	circadian	ADJ
cusj-7408	162	26	rhythms	rhythm	NOUN
cusj-7408	162	27	(	(	PUNCT
cusj-7408	162	28	figure	figure	NOUN
cusj-7408	162	29	3b	3b	NUM
cusj-7408	162	30	)	)	PUNCT
cusj-7408	162	31	.	.	PUNCT
cusj-7408	163	1	additionally	additionally	ADV
cusj-7408	163	2	,	,	PUNCT
cusj-7408	163	3	we	we	PRON
cusj-7408	163	4	see	see	VERB
cusj-7408	163	5	od	od	PROPN
cusj-7408	163	6	levels	level	NOUN
cusj-7408	163	7	of	of	ADP
cusj-7408	163	8	hfd	hfd	PROPN
cusj-7408	163	9	groups	group	NOUN
cusj-7408	163	10	to	to	PART
cusj-7408	163	11	be	be	AUX
cusj-7408	163	12	at	at	ADP
cusj-7408	163	13	levels	level	NOUN
cusj-7408	163	14	closer	close	ADJ
cusj-7408	163	15	to	to	PART
cusj-7408	163	16	control	control	VERB
cusj-7408	163	17	group	group	NOUN
cusj-7408	163	18	zt14	zt14	PROPN
cusj-7408	163	19	reaffirming	reaffirm	VERB
cusj-7408	163	20	previous	previous	ADJ
cusj-7408	163	21	data	datum	NOUN
cusj-7408	163	22	showing	show	VERB
cusj-7408	163	23	increased	increase	VERB
cusj-7408	163	24	permeability	permeability	NOUN
cusj-7408	163	25	in	in	ADP
cusj-7408	163	26	hfd	hfd	PROPN
cusj-7408	163	27	mice	mouse	NOUN
cusj-7408	163	28	(	(	PUNCT
cusj-7408	163	29	figure	figure	NOUN
cusj-7408	163	30	3b	3b	NUM
cusj-7408	163	31	)	)	PUNCT
cusj-7408	163	32	.	.	PUNCT
cusj-7408	164	1	when	when	SCONJ
cusj-7408	164	2	the	the	DET
cusj-7408	164	3	ussing	ussing	ADJ
cusj-7408	164	4	chamber	chamber	NOUN
cusj-7408	164	5	is	be	AUX
cusj-7408	164	6	performed	perform	VERB
cusj-7408	164	7	on	on	ADP
cusj-7408	164	8	small	small	ADJ
cusj-7408	164	9	intestine	intestine	NOUN
cusj-7408	164	10	samples	sample	NOUN
cusj-7408	164	11	,	,	PUNCT
cusj-7408	164	12	we	we	PRON
cusj-7408	164	13	likewise	likewise	ADV
cusj-7408	164	14	see	see	VERB
cusj-7408	164	15	no	no	DET
cusj-7408	164	16	significance	significance	NOUN
cusj-7408	164	17	between	between	ADP
cusj-7408	164	18	hfd	hfd	PROPN
cusj-7408	164	19	groups	group	NOUN
cusj-7408	164	20	and	and	CCONJ
cusj-7408	164	21	overall	overall	ADJ
cusj-7408	164	22	hfd	hfd	PROPN
cusj-7408	164	23	permeability	permeability	NOUN
cusj-7408	164	24	levels	level	NOUN
cusj-7408	164	25	correlate	correlate	VERB
cusj-7408	164	26	figure	figure	NOUN
cusj-7408	164	27	3	3	NUM
cusj-7408	164	28	.	.	PUNCT
cusj-7408	164	29	metabolic	metabolic	NOUN
cusj-7408	164	30	syndrome	syndrome	NOUN
cusj-7408	164	31	induced	induce	VERB
cusj-7408	164	32	by	by	ADP
cusj-7408	164	33	hfd	hfd	PROPN
cusj-7408	164	34	results	result	NOUN
cusj-7408	164	35	in	in	ADP
cusj-7408	164	36	circadian	circadian	ADJ
cusj-7408	164	37	disruption	disruption	NOUN
cusj-7408	164	38	and	and	CCONJ
cusj-7408	164	39	intestinal	intestinal	ADJ
cusj-7408	164	40	barrier	barrier	NOUN
cusj-7408	164	41	dysfunction	dysfunction	NOUN
cusj-7408	164	42	.	.	PUNCT
cusj-7408	165	1	(	(	PUNCT
cusj-7408	165	2	a	a	X
cusj-7408	165	3	)	)	PUNCT
cusj-7408	165	4	schematic	schematic	ADJ
cusj-7408	165	5	showing	show	VERB
cusj-7408	165	6	the	the	DET
cusj-7408	165	7	typical	typical	ADJ
cusj-7408	165	8	configuration	configuration	NOUN
cusj-7408	165	9	of	of	ADP
cusj-7408	165	10	a	a	DET
cusj-7408	165	11	circa	circa	NOUN
cusj-7408	165	12	-	-	PUNCT
cusj-7408	165	13	dian	dian	ADJ
cusj-7408	165	14	cabinet	cabinet	NOUN
cusj-7408	165	15	.	.	PUNCT
cusj-7408	166	1	(	(	PUNCT
cusj-7408	166	2	b	b	X
cusj-7408	166	3	)	)	PUNCT
cusj-7408	166	4	fitc	fitc	NOUN
cusj-7408	166	5	(	(	PUNCT
cusj-7408	166	6	fluorescein	fluorescein	NOUN
cusj-7408	166	7	isothiocyanate)-dextran	isothiocyanate)-dextran	PROPN
cusj-7408	166	8	recovered	recover	VERB
cusj-7408	166	9	from	from	ADP
cusj-7408	166	10	the	the	DET
cusj-7408	166	11	serum	serum	NOUN
cusj-7408	166	12	of	of	ADP
cusj-7408	166	13	hfd	hfd	PROPN
cusj-7408	166	14	mice	mouse	NOUN
cusj-7408	166	15	at	at	ADP
cusj-7408	166	16	different	different	ADJ
cusj-7408	166	17	zt	zt	PROPN
cusj-7408	166	18	times	times	PROPN
cusj-7408	166	19	and	and	CCONJ
cusj-7408	166	20	their	their	PRON
cusj-7408	166	21	respective	respective	ADJ
cusj-7408	166	22	controls	control	NOUN
cusj-7408	166	23	.	.	PUNCT
cusj-7408	167	1	(	(	PUNCT
cusj-7408	167	2	c	c	X
cusj-7408	167	3	)	)	PUNCT
cusj-7408	167	4	ussing	usse	VERB
cusj-7408	167	5	chamber	chamber	NOUN
cusj-7408	167	6	recording	recording	NOUN
cusj-7408	167	7	of	of	ADP
cusj-7408	167	8	small	small	ADJ
cusj-7408	167	9	intestines	intestine	NOUN
cusj-7408	167	10	of	of	ADP
cusj-7408	167	11	hfd	hfd	PROPN
cusj-7408	167	12	mice	mouse	NOUN
cusj-7408	167	13	at	at	ADP
cusj-7408	167	14	different	different	ADJ
cusj-7408	167	15	zt	zt	PROPN
cusj-7408	167	16	times	times	PROPN
cusj-7408	167	17	and	and	CCONJ
cusj-7408	167	18	their	their	PRON
cusj-7408	167	19	respective	respective	ADJ
cusj-7408	167	20	controls	control	NOUN
cusj-7408	167	21	.	.	PUNCT
cusj-7408	168	1	means	mean	VERB
cusj-7408	168	2	±	±	NUM
cusj-7408	168	3	sd	sd	NOUN
cusj-7408	168	4	are	be	AUX
cusj-7408	168	5	plotted	plot	VERB
cusj-7408	168	6	.	.	PUNCT
cusj-7408	169	1	*	*	PUNCT
cusj-7408	169	2	p	p	X
cusj-7408	169	3	<	<	X
cusj-7408	169	4	0.05	0.05	NUM
cusj-7408	169	5	,	,	PUNCT
cusj-7408	169	6	*	*	PUNCT
cusj-7408	169	7	*	*	PUNCT
cusj-7408	169	8	p	p	X
cusj-7408	169	9	<	<	X
cusj-7408	169	10	0.01	0.01	NUM
cusj-7408	169	11	,	,	PUNCT
cusj-7408	169	12	*	*	PUNCT
cusj-7408	169	13	*	*	PUNCT
cusj-7408	169	14	*	*	PUNCT
cusj-7408	169	15	p	p	X
cusj-7408	169	16	<	<	X
cusj-7408	169	17	0.001	0.001	NUM
cusj-7408	169	18	,	,	PUNCT
cusj-7408	169	19	*	*	PUNCT
cusj-7408	169	20	*	*	PUNCT
cusj-7408	169	21	*	*	PUNCT
cusj-7408	169	22	*	*	PUNCT
cusj-7408	169	23	p	p	X
cusj-7408	169	24	<	<	X
cusj-7408	169	25	0.0001	0.0001	NUM
cusj-7408	169	26	by	by	ADP
cusj-7408	169	27	mann	mann	PROPN
cusj-7408	169	28	-	-	PUNCT
cusj-7408	169	29	whitney	whitney	PROPN
cusj-7408	169	30	u	u	PROPN
cusj-7408	169	31	test	test	NOUN
cusj-7408	169	32	.	.	PUNCT
cusj-7408	170	1	figure	figure	NOUN
cusj-7408	170	2	3b	3b	NOUN
cusj-7408	170	3	and	and	CCONJ
cusj-7408	170	4	3c	3c	NUM
cusj-7408	170	5	:	:	PUNCT
cusj-7408	170	6	2	2	NUM
cusj-7408	170	7	-	-	PUNCT
cusj-7408	170	8	way	way	NOUN
cusj-7408	170	9	anova	anova	PROPN
cusj-7408	170	10	test	test	NOUN
cusj-7408	170	11	.	.	PUNCT
cusj-7408	171	1	a	a	DET
cusj-7408	171	2	b	b	PROPN
cusj-7408	171	3	c	c	PROPN
cusj-7408	171	4	13	13	NUM
cusj-7408	171	5	columbia	columbia	PROPN
cusj-7408	171	6	undergraduate	undergraduate	PROPN
cusj-7408	171	7	science	science	PROPN
cusj-7408	171	8	journal	journal	PROPN
cusj-7408	171	9	vol	vol	NOUN
cusj-7408	171	10	.	.	PROPN
cusj-7408	171	11	15	15	NUM
cusj-7408	171	12	,	,	PUNCT
cusj-7408	171	13	2021	2021	NUM
cusj-7408	171	14	pinker	pinker	PROPN
cusj-7408	171	15	et	et	PROPN
cusj-7408	171	16	.	.	PUNCT
cusj-7408	172	1	al	al	PROPN
cusj-7408	172	2	.	.	PROPN
cusj-7408	173	1	more	more	ADV
cusj-7408	173	2	strongly	strongly	ADV
cusj-7408	173	3	with	with	ADP
cusj-7408	173	4	zt14	zt14	PROPN
cusj-7408	173	5	than	than	ADP
cusj-7408	173	6	zt2	zt2	PROPN
cusj-7408	173	7	(	(	PUNCT
cusj-7408	173	8	figure	figure	NOUN
cusj-7408	173	9	3c	3c	NUM
cusj-7408	173	10	)	)	PUNCT
cusj-7408	173	11	.	.	PUNCT
cusj-7408	174	1	together	together	ADV
cusj-7408	174	2	,	,	PUNCT
cusj-7408	174	3	these	these	DET
cusj-7408	174	4	observed	observe	VERB
cusj-7408	174	5	results	result	NOUN
cusj-7408	174	6	draw	draw	VERB
cusj-7408	174	7	attention	attention	NOUN
cusj-7408	174	8	to	to	ADP
cusj-7408	174	9	a	a	DET
cusj-7408	174	10	serious	serious	ADJ
cusj-7408	174	11	issue	issue	NOUN
cusj-7408	174	12	.	.	PUNCT
cusj-7408	175	1	metabolic	metabolic	NOUN
cusj-7408	175	2	syndromes	syndrome	NOUN
cusj-7408	175	3	,	,	PUNCT
cusj-7408	175	4	which	which	PRON
cusj-7408	175	5	are	be	AUX
cusj-7408	175	6	usually	usually	ADV
cusj-7408	175	7	onset	onset	VERB
cusj-7408	175	8	by	by	ADP
cusj-7408	175	9	poor	poor	ADJ
cusj-7408	175	10	diets	diet	NOUN
cusj-7408	175	11	such	such	ADJ
cusj-7408	175	12	as	as	ADP
cusj-7408	175	13	those	those	PRON
cusj-7408	175	14	high	high	ADJ
cusj-7408	175	15	in	in	ADP
cusj-7408	175	16	fat	fat	NOUN
cusj-7408	175	17	,	,	PUNCT
cusj-7408	175	18	are	be	AUX
cusj-7408	175	19	only	only	ADV
cusj-7408	175	20	exacerbated	exacerbate	VERB
cusj-7408	175	21	by	by	ADP
cusj-7408	175	22	the	the	DET
cusj-7408	175	23	same	same	ADJ
cusj-7408	175	24	stimuli	stimulus	NOUN
cusj-7408	175	25	that	that	PRON
cusj-7408	175	26	caused	cause	VERB
cusj-7408	175	27	the	the	DET
cusj-7408	175	28	development	development	NOUN
cusj-7408	175	29	of	of	ADP
cusj-7408	175	30	the	the	DET
cusj-7408	175	31	disease	disease	NOUN
cusj-7408	175	32	.	.	PUNCT
cusj-7408	176	1	our	our	PRON
cusj-7408	176	2	data	datum	NOUN
cusj-7408	176	3	signifies	signify	VERB
cusj-7408	176	4	metabolic	metabolic	NOUN
cusj-7408	176	5	syndromes	syndrome	NOUN
cusj-7408	176	6	’	'	PUNCT
cusj-7408	176	7	role	role	NOUN
cusj-7408	176	8	in	in	ADP
cusj-7408	176	9	both	both	PRON
cusj-7408	176	10	disrupting	disrupt	VERB
cusj-7408	176	11	circadian	circadian	ADJ
cusj-7408	176	12	rhythms	rhythm	NOUN
cusj-7408	176	13	and	and	CCONJ
cusj-7408	176	14	heightening	heighten	VERB
cusj-7408	176	15	intestinal	intestinal	ADJ
cusj-7408	176	16	barrier	barrier	NOUN
cusj-7408	176	17	permeability	permeability	NOUN
cusj-7408	176	18	that	that	PRON
cusj-7408	176	19	can	can	AUX
cusj-7408	176	20	lead	lead	VERB
cusj-7408	176	21	to	to	ADP
cusj-7408	176	22	increased	increase	VERB
cusj-7408	176	23	inflammation	inflammation	NOUN
cusj-7408	176	24	and	and	CCONJ
cusj-7408	176	25	infection	infection	NOUN
cusj-7408	176	26	.	.	PUNCT
cusj-7408	177	1	discussion	discussion	NOUN
cusj-7408	177	2	&	&	CCONJ
cusj-7408	177	3	conclusion	conclusion	NOUN
cusj-7408	177	4	in	in	ADP
cusj-7408	177	5	this	this	DET
cusj-7408	177	6	study	study	NOUN
cusj-7408	177	7	,	,	PUNCT
cusj-7408	177	8	we	we	PRON
cusj-7408	177	9	describe	describe	VERB
cusj-7408	177	10	that	that	SCONJ
cusj-7408	177	11	the	the	DET
cusj-7408	177	12	mammalian	mammalian	ADJ
cusj-7408	177	13	intestinal	intestinal	ADJ
cusj-7408	177	14	barrier	barrier	NOUN
cusj-7408	177	15	function	function	NOUN
cusj-7408	177	16	displays	display	VERB
cusj-7408	177	17	diurnal	diurnal	ADJ
cusj-7408	177	18	oscillations	oscillation	NOUN
cusj-7408	177	19	and	and	CCONJ
cusj-7408	177	20	is	be	AUX
cusj-7408	177	21	dependent	dependent	ADJ
cusj-7408	177	22	on	on	ADP
cusj-7408	177	23	microbiome	microbiome	ADJ
cusj-7408	177	24	composition	composition	NOUN
cusj-7408	177	25	.	.	PUNCT
cusj-7408	178	1	if	if	SCONJ
cusj-7408	178	2	microbiome	microbiome	ADJ
cusj-7408	178	3	composition	composition	NOUN
cusj-7408	178	4	is	be	AUX
cusj-7408	178	5	distorted	distort	VERB
cusj-7408	178	6	,	,	PUNCT
cusj-7408	178	7	as	as	ADP
cusj-7408	178	8	in	in	ADP
cusj-7408	178	9	the	the	DET
cusj-7408	178	10	case	case	NOUN
cusj-7408	178	11	of	of	ADP
cusj-7408	178	12	antibiotic	antibiotic	ADJ
cusj-7408	178	13	treatment	treatment	NOUN
cusj-7408	178	14	or	or	CCONJ
cusj-7408	178	15	hfd	hfd	PROPN
cusj-7408	178	16	,	,	PUNCT
cusj-7408	178	17	we	we	PRON
cusj-7408	178	18	see	see	VERB
cusj-7408	178	19	alterations	alteration	NOUN
cusj-7408	178	20	in	in	ADP
cusj-7408	178	21	intestinal	intestinal	ADJ
cusj-7408	178	22	barrier	barrier	NOUN
cusj-7408	178	23	integrity	integrity	NOUN
cusj-7408	178	24	as	as	ADV
cusj-7408	178	25	well	well	ADV
cusj-7408	178	26	as	as	ADP
cusj-7408	178	27	disruptions	disruption	NOUN
cusj-7408	178	28	in	in	ADP
cusj-7408	178	29	the	the	DET
cusj-7408	178	30	circadian	circadian	ADJ
cusj-7408	178	31	rhythms	rhythm	NOUN
cusj-7408	178	32	of	of	ADP
cusj-7408	178	33	epithelial	epithelial	ADJ
cusj-7408	178	34	permeability	permeability	NOUN
cusj-7408	178	35	.	.	PUNCT
cusj-7408	179	1	while	while	SCONJ
cusj-7408	179	2	previous	previous	ADJ
cusj-7408	179	3	studies	study	NOUN
cusj-7408	179	4	sought	seek	VERB
cusj-7408	179	5	to	to	PART
cusj-7408	179	6	understand	understand	VERB
cusj-7408	179	7	the	the	DET
cusj-7408	179	8	consequences	consequence	NOUN
cusj-7408	179	9	,	,	PUNCT
cusj-7408	179	10	diurnal	diurnal	ADJ
cusj-7408	179	11	disruption	disruption	NOUN
cusj-7408	179	12	has	have	VERB
cusj-7408	179	13	on	on	ADP
cusj-7408	179	14	microbial	microbial	ADJ
cusj-7408	179	15	composition	composition	NOUN
cusj-7408	179	16	,	,	PUNCT
cusj-7408	179	17	here	here	ADV
cusj-7408	179	18	we	we	PRON
cusj-7408	179	19	found	find	VERB
cusj-7408	179	20	direct	direct	ADJ
cusj-7408	179	21	evidence	evidence	NOUN
cusj-7408	179	22	of	of	ADP
cusj-7408	179	23	the	the	DET
cusj-7408	179	24	role	role	NOUN
cusj-7408	179	25	microbial	microbial	ADJ
cusj-7408	179	26	composition	composition	NOUN
cusj-7408	179	27	plays	play	VERB
cusj-7408	179	28	in	in	ADP
cusj-7408	179	29	intestinal	intestinal	ADJ
cusj-7408	179	30	permeability	permeability	NOUN
cusj-7408	179	31	.	.	PUNCT
cusj-7408	180	1	next	next	ADV
cusj-7408	180	2	,	,	PUNCT
cusj-7408	180	3	we	we	PRON
cusj-7408	180	4	wanted	want	VERB
cusj-7408	180	5	to	to	PART
cusj-7408	180	6	study	study	VERB
cusj-7408	180	7	the	the	DET
cusj-7408	180	8	direct	direct	ADJ
cusj-7408	180	9	implications	implication	NOUN
cusj-7408	180	10	distorting	distort	VERB
cusj-7408	180	11	circadian	circadian	ADJ
cusj-7408	180	12	rhythms	rhythm	NOUN
cusj-7408	180	13	,	,	PUNCT
cusj-7408	180	14	either	either	CCONJ
cusj-7408	180	15	with	with	ADP
cusj-7408	180	16	genetic	genetic	ADJ
cusj-7408	180	17	clock	clock	NOUN
cusj-7408	180	18	deficiency	deficiency	NOUN
cusj-7408	180	19	or	or	CCONJ
cusj-7408	180	20	time	time	NOUN
cusj-7408	180	21	-	-	PUNCT
cusj-7408	180	22	shifted	shift	VERB
cusj-7408	180	23	induced	induced	ADJ
cusj-7408	180	24	jet	jet	NOUN
cusj-7408	180	25	lag	lag	NOUN
cusj-7408	180	26	,	,	PUNCT
cusj-7408	180	27	have	have	VERB
cusj-7408	180	28	on	on	ADP
cusj-7408	180	29	intestinal	intestinal	ADJ
cusj-7408	180	30	barrier	barrier	NOUN
cusj-7408	180	31	function	function	NOUN
cusj-7408	180	32	.	.	PUNCT
cusj-7408	181	1	we	we	PRON
cusj-7408	181	2	not	not	PART
cusj-7408	181	3	only	only	ADV
cusj-7408	181	4	found	find	VERB
cusj-7408	181	5	that	that	SCONJ
cusj-7408	181	6	these	these	DET
cusj-7408	181	7	conditions	condition	NOUN
cusj-7408	181	8	significantly	significantly	ADV
cusj-7408	181	9	impaired	impair	VERB
cusj-7408	181	10	the	the	DET
cusj-7408	181	11	circadian	circadian	ADJ
cusj-7408	181	12	rhythms	rhythm	NOUN
cusj-7408	181	13	of	of	ADP
cusj-7408	181	14	permeability	permeability	NOUN
cusj-7408	181	15	,	,	PUNCT
cusj-7408	181	16	but	but	CCONJ
cusj-7408	181	17	also	also	ADV
cusj-7408	181	18	,	,	PUNCT
cusj-7408	181	19	increased	increase	VERB
cusj-7408	181	20	overall	overall	ADJ
cusj-7408	181	21	permeability	permeability	NOUN
cusj-7408	181	22	resulting	result	VERB
cusj-7408	181	23	in	in	ADP
cusj-7408	181	24	greater	great	ADJ
cusj-7408	181	25	pathobiont	pathobiont	NOUN
cusj-7408	181	26	exposure	exposure	NOUN
cusj-7408	181	27	and	and	CCONJ
cusj-7408	181	28	inflammation	inflammation	NOUN
cusj-7408	181	29	.	.	PUNCT
cusj-7408	182	1	lastly	lastly	ADV
cusj-7408	182	2	,	,	PUNCT
cusj-7408	182	3	we	we	PRON
cusj-7408	182	4	found	find	VERB
cusj-7408	182	5	that	that	SCONJ
cusj-7408	182	6	inducing	induce	VERB
cusj-7408	182	7	metabolic	metabolic	ADJ
cusj-7408	182	8	syndromes	syndrome	NOUN
cusj-7408	182	9	via	via	ADP
cusj-7408	182	10	hfd	hfd	PROPN
cusj-7408	182	11	intervention	intervention	PROPN
cusj-7408	182	12	disrupts	disrupt	VERB
cusj-7408	182	13	circadian	circadian	ADJ
cusj-7408	182	14	rhythms	rhythm	NOUN
cusj-7408	182	15	in	in	ADP
cusj-7408	182	16	the	the	DET
cusj-7408	182	17	intestinal	intestinal	ADJ
cusj-7408	182	18	barrier	barrier	NOUN
cusj-7408	182	19	as	as	ADV
cusj-7408	182	20	well	well	ADV
cusj-7408	182	21	as	as	ADP
cusj-7408	182	22	causes	cause	VERB
cusj-7408	182	23	significant	significant	ADJ
cusj-7408	182	24	barrier	barrier	NOUN
cusj-7408	182	25	dysfunction	dysfunction	NOUN
cusj-7408	182	26	resulting	result	VERB
cusj-7408	182	27	in	in	ADP
cusj-7408	182	28	increased	increase	VERB
cusj-7408	182	29	epithelial	epithelial	ADJ
cusj-7408	182	30	permeability	permeability	NOUN
cusj-7408	182	31	.	.	PUNCT
cusj-7408	183	1	altogether	altogether	ADV
cusj-7408	183	2	,	,	PUNCT
cusj-7408	183	3	these	these	DET
cusj-7408	183	4	studies	study	NOUN
cusj-7408	183	5	have	have	AUX
cusj-7408	183	6	uncovered	uncover	VERB
cusj-7408	183	7	numerous	numerous	ADJ
cusj-7408	183	8	future	future	ADJ
cusj-7408	183	9	paths	path	NOUN
cusj-7408	183	10	.	.	PUNCT
cusj-7408	184	1	while	while	SCONJ
cusj-7408	184	2	this	this	DET
cusj-7408	184	3	study	study	NOUN
cusj-7408	184	4	has	have	AUX
cusj-7408	184	5	broadly	broadly	ADV
cusj-7408	184	6	implicated	implicate	VERB
cusj-7408	184	7	microbiome	microbiome	ADJ
cusj-7408	184	8	composition	composition	NOUN
cusj-7408	184	9	as	as	ADP
cusj-7408	184	10	a	a	DET
cusj-7408	184	11	mediator	mediator	NOUN
cusj-7408	184	12	of	of	ADP
cusj-7408	184	13	gut	gut	NOUN
cusj-7408	184	14	permeability	permeability	NOUN
cusj-7408	184	15	,	,	PUNCT
cusj-7408	184	16	in	in	ADP
cusj-7408	184	17	order	order	NOUN
cusj-7408	184	18	to	to	PART
cusj-7408	184	19	learn	learn	VERB
cusj-7408	184	20	more	more	ADJ
cusj-7408	184	21	about	about	ADP
cusj-7408	184	22	the	the	DET
cusj-7408	184	23	key	key	ADJ
cusj-7408	184	24	bacterial	bacterial	ADJ
cusj-7408	184	25	players	player	NOUN
cusj-7408	184	26	in	in	ADP
cusj-7408	184	27	permeability	permeability	NOUN
cusj-7408	184	28	mediation	mediation	NOUN
cusj-7408	184	29	,	,	PUNCT
cusj-7408	184	30	we	we	PRON
cusj-7408	184	31	can	can	AUX
cusj-7408	184	32	perform	perform	VERB
cusj-7408	184	33	sequencing	sequence	VERB
cusj-7408	184	34	on	on	ADP
cusj-7408	184	35	the	the	DET
cusj-7408	184	36	microbial	microbial	ADJ
cusj-7408	184	37	compositions	composition	NOUN
cusj-7408	184	38	found	find	VERB
cusj-7408	184	39	in	in	ADP
cusj-7408	184	40	our	our	PRON
cusj-7408	184	41	antibiotic	antibiotic	ADJ
cusj-7408	184	42	treated	treat	VERB
cusj-7408	184	43	groups	group	NOUN
cusj-7408	184	44	to	to	PART
cusj-7408	184	45	reveal	reveal	VERB
cusj-7408	184	46	the	the	DET
cusj-7408	184	47	unique	unique	ADJ
cusj-7408	184	48	bacteria	bacteria	NOUN
cusj-7408	184	49	having	have	VERB
cusj-7408	184	50	the	the	DET
cusj-7408	184	51	biggest	big	ADJ
cusj-7408	184	52	impact	impact	NOUN
cusj-7408	184	53	on	on	ADP
cusj-7408	184	54	reducing	reduce	VERB
cusj-7408	184	55	or	or	CCONJ
cusj-7408	184	56	increasing	increase	VERB
cusj-7408	184	57	permeability	permeability	NOUN
cusj-7408	184	58	.	.	PUNCT
cusj-7408	185	1	understanding	understanding	NOUN
cusj-7408	185	2	which	which	DET
cusj-7408	185	3	bacteria	bacteria	NOUN
cusj-7408	185	4	to	to	PART
cusj-7408	185	5	promote	promote	VERB
cusj-7408	185	6	and	and	CCONJ
cusj-7408	185	7	which	which	PRON
cusj-7408	185	8	to	to	PART
cusj-7408	185	9	remove	remove	VERB
cusj-7408	185	10	in	in	ADP
cusj-7408	185	11	the	the	DET
cusj-7408	185	12	microbiota	microbiota	NOUN
cusj-7408	185	13	could	could	AUX
cusj-7408	185	14	be	be	AUX
cusj-7408	185	15	pivotal	pivotal	ADJ
cusj-7408	185	16	in	in	ADP
cusj-7408	185	17	suppressing	suppress	VERB
cusj-7408	185	18	symptoms	symptom	NOUN
cusj-7408	185	19	in	in	ADP
cusj-7408	185	20	patients	patient	NOUN
cusj-7408	185	21	with	with	ADP
cusj-7408	185	22	ibd	ibd	PROPN
cusj-7408	185	23	and	and	CCONJ
cusj-7408	185	24	metabolic	metabolic	NOUN
cusj-7408	185	25	syndromes	syndrome	NOUN
cusj-7408	185	26	,	,	PUNCT
cusj-7408	185	27	to	to	PART
cusj-7408	185	28	name	name	VERB
cusj-7408	185	29	a	a	DET
cusj-7408	185	30	few	few	ADJ
cusj-7408	185	31	,	,	PUNCT
cusj-7408	185	32	caused	cause	VERB
cusj-7408	185	33	by	by	ADP
cusj-7408	185	34	leakages	leakage	NOUN
cusj-7408	185	35	in	in	ADP
cusj-7408	185	36	the	the	DET
cusj-7408	185	37	intestinal	intestinal	ADJ
cusj-7408	185	38	epithelial	epithelial	NOUN
cusj-7408	185	39	.	.	PUNCT
cusj-7408	186	1	exploiting	exploit	VERB
cusj-7408	186	2	antibiotic	antibiotic	ADJ
cusj-7408	186	3	or	or	CCONJ
cusj-7408	186	4	probiotic	probiotic	ADJ
cusj-7408	186	5	treatments	treatment	NOUN
cusj-7408	186	6	to	to	PART
cusj-7408	186	7	target	target	VERB
cusj-7408	186	8	these	these	DET
cusj-7408	186	9	bacteria	bacteria	NOUN
cusj-7408	186	10	could	could	AUX
cusj-7408	186	11	help	help	VERB
cusj-7408	186	12	combat	combat	NOUN
cusj-7408	186	13	diseases	disease	NOUN
cusj-7408	186	14	exacerbated	exacerbate	VERB
cusj-7408	186	15	by	by	ADP
cusj-7408	186	16	gut	gut	NOUN
cusj-7408	186	17	leakiness	leakiness	NOUN
cusj-7408	186	18	.	.	PUNCT
cusj-7408	187	1	lastly	lastly	ADV
cusj-7408	187	2	,	,	PUNCT
cusj-7408	187	3	our	our	PRON
cusj-7408	187	4	observations	observation	NOUN
cusj-7408	187	5	showing	show	VERB
cusj-7408	187	6	intestinal	intestinal	ADJ
cusj-7408	187	7	permeability	permeability	NOUN
cusj-7408	187	8	functioning	function	VERB
cusj-7408	187	9	under	under	ADP
cusj-7408	187	10	diurnal	diurnal	ADJ
cusj-7408	187	11	oscillations	oscillation	NOUN
cusj-7408	187	12	has	have	VERB
cusj-7408	187	13	applications	application	NOUN
cusj-7408	187	14	from	from	ADP
cusj-7408	187	15	drug	drug	NOUN
cusj-7408	187	16	consumption	consumption	NOUN
cusj-7408	187	17	to	to	ADP
cusj-7408	187	18	nutritional	nutritional	ADJ
cusj-7408	187	19	/	/	SYM
cusj-7408	187	20	dietary	dietary	ADJ
cusj-7408	187	21	strategies	strategy	NOUN
cusj-7408	187	22	.	.	PUNCT
cusj-7408	188	1	further	far	ADV
cusj-7408	188	2	unravelling	unravel	VERB
cusj-7408	188	3	the	the	DET
cusj-7408	188	4	roles	role	NOUN
cusj-7408	188	5	,	,	PUNCT
cusj-7408	188	6	regulators	regulator	NOUN
cusj-7408	188	7	and	and	CCONJ
cusj-7408	188	8	mechanisms	mechanism	NOUN
cusj-7408	188	9	of	of	ADP
cusj-7408	188	10	intestinal	intestinal	ADJ
cusj-7408	188	11	permeability	permeability	NOUN
cusj-7408	188	12	could	could	AUX
cusj-7408	188	13	serve	serve	VERB
cusj-7408	188	14	to	to	ADP
cusj-7408	188	15	one	one	NUM
cusj-7408	188	16	day	day	NOUN
cusj-7408	188	17	aid	aid	NOUN
cusj-7408	188	18	therapies	therapy	NOUN
cusj-7408	188	19	for	for	ADP
cusj-7408	188	20	illnesses	illness	NOUN
cusj-7408	188	21	affected	affect	VERB
cusj-7408	188	22	by	by	ADP
cusj-7408	188	23	the	the	DET
cusj-7408	188	24	“	"	PUNCT
cusj-7408	188	25	leaky	leaky	ADJ
cusj-7408	188	26	gut	gut	NOUN
cusj-7408	188	27	”	"	PUNCT
cusj-7408	188	28	syndrome	syndrome	NOUN
cusj-7408	188	29	.	.	PUNCT
cusj-7408	189	1	author	author	NOUN
cusj-7408	189	2	information	information	NOUN
cusj-7408	189	3	corresponding	correspond	VERB
cusj-7408	189	4	author	author	NOUN
cusj-7408	189	5	*	*	PUNCT
cusj-7408	189	6	elisha	elisha	PROPN
cusj-7408	189	7	pinker	pinker	ADV
cusj-7408	189	8	ep2858@columbia.edu	ep2858@columbia.edu	NOUN
cusj-7408	189	9	funding	funding	NOUN
cusj-7408	189	10	sources	sources	PROPN
cusj-7408	189	11	columbia	columbia	PROPN
cusj-7408	189	12	college	college	NOUN
cusj-7408	189	13	class	class	NOUN
cusj-7408	189	14	of	of	ADP
cusj-7408	189	15	1939	1939	NUM
cusj-7408	189	16	fellowship	fellowship	NOUN
cusj-7408	189	17	competing	compete	VERB
cusj-7408	189	18	interests	interest	NOUN
cusj-7408	189	19	the	the	DET
cusj-7408	189	20	authors	author	NOUN
cusj-7408	189	21	declare	declare	VERB
cusj-7408	189	22	no	no	DET
cusj-7408	189	23	competing	compete	VERB
cusj-7408	189	24	financial	financial	ADJ
cusj-7408	189	25	and	and	CCONJ
cusj-7408	189	26	non	non	ADJ
cusj-7408	189	27	-	-	ADJ
cusj-7408	189	28	financial	financial	ADJ
cusj-7408	189	29	interests	interest	NOUN
cusj-7408	189	30	.	.	PUNCT
cusj-7408	190	1	acknowledgments	acknowledgment	NOUN
cusj-7408	190	2	e.p	e.p	PROPN
cusj-7408	190	3	.	.	PROPN
cusj-7408	190	4	would	would	AUX
cusj-7408	190	5	like	like	VERB
cusj-7408	190	6	to	to	PART
cusj-7408	190	7	thank	thank	VERB
cusj-7408	190	8	columbia	columbia	PROPN
cusj-7408	190	9	college	college	PROPN
cusj-7408	190	10	and	and	CCONJ
cusj-7408	190	11	the	the	DET
cusj-7408	190	12	weizmann	weizmann	PROPN
cusj-7408	190	13	institute	institute	PROPN
cusj-7408	190	14	of	of	ADP
cusj-7408	190	15	science	science	NOUN
cusj-7408	190	16	for	for	ADP
cusj-7408	190	17	supporting	support	VERB
cusj-7408	190	18	this	this	DET
cusj-7408	190	19	research	research	NOUN
cusj-7408	190	20	.	.	PUNCT
cusj-7408	191	1	references	reference	NOUN
cusj-7408	191	2	[	[	X
cusj-7408	191	3	1	1	NUM
cusj-7408	191	4	]	]	X
cusj-7408	191	5	marietta	marietta	PROPN
cusj-7408	191	6	e	e	PROPN
cusj-7408	191	7	,	,	PUNCT
cusj-7408	191	8	rishi	rishi	PROPN
cusj-7408	191	9	a	a	PRON
cusj-7408	191	10	,	,	PUNCT
cusj-7408	191	11	taneja	taneja	PROPN
cusj-7408	191	12	v.	v.	ADP
cusj-7408	191	13	immunogenetic	immunogenetic	ADJ
cusj-7408	191	14	control	control	NOUN
cusj-7408	191	15	of	of	ADP
cusj-7408	191	16	the	the	DET
cusj-7408	191	17	intestinal	intestinal	ADJ
cusj-7408	191	18	microbiota	microbiota	NOUN
cusj-7408	191	19	.	.	PUNCT
cusj-7408	192	1	immunology	immunology	NOUN
cusj-7408	192	2	.	.	PUNCT
cusj-7408	193	1	2015;145(3):313	2015;145(3):313	NUM
cusj-7408	193	2	-	-	SYM
cusj-7408	193	3	322	322	NUM
cusj-7408	193	4	.	.	PUNCT
cusj-7408	194	1	doi:10.1111/	doi:10.1111/	PROPN
cusj-7408	194	2	imm.12474	imm.12474	PROPN
cusj-7408	194	3	.	.	PUNCT
cusj-7408	195	1	[	[	X
cusj-7408	195	2	2	2	NUM
cusj-7408	195	3	]	]	PUNCT
cusj-7408	195	4	neish	neish	NOUN
cusj-7408	195	5	as	as	ADP
cusj-7408	195	6	.	.	PUNCT
cusj-7408	195	7	mucosal	mucosal	NOUN
cusj-7408	195	8	immunity	immunity	NOUN
cusj-7408	195	9	and	and	CCONJ
cusj-7408	195	10	the	the	DET
cusj-7408	195	11	microbiome	microbiome	NOUN
cusj-7408	195	12	.	.	PUNCT
cusj-7408	196	1	annals	annal	NOUN
cusj-7408	196	2	of	of	ADP
cusj-7408	196	3	the	the	DET
cusj-7408	196	4	american	american	PROPN
cusj-7408	196	5	thoracic	thoracic	NOUN
cusj-7408	196	6	society	society	NOUN
cusj-7408	196	7	.	.	PUNCT
cusj-7408	197	1	2014;11(suppl	2014;11(suppl	PROPN
cusj-7408	197	2	1):s28	1):s28	NUM
cusj-7408	197	3	-	-	PUNCT
cusj-7408	197	4	s32	s32	PROPN
cusj-7408	197	5	.	.	PUNCT
cusj-7408	198	1	doi:10.1513	doi:10.1513	PROPN
cusj-7408	198	2	/	/	SYM
cusj-7408	199	1	annalsats.201306	annalsats.201306	NOUN
cusj-7408	199	2	-	-	PUNCT
cusj-7408	199	3	161	161	NUM
cusj-7408	199	4	mg	mg	NUM
cusj-7408	199	5	.	.	PUNCT
cusj-7408	200	1	14	14	NUM
cusj-7408	200	2	columbia	columbia	PROPN
cusj-7408	200	3	undergraduate	undergraduate	PROPN
cusj-7408	200	4	science	science	PROPN
cusj-7408	200	5	journal	journal	PROPN
cusj-7408	200	6	vol	vol	NOUN
cusj-7408	200	7	.	.	PROPN
cusj-7408	200	8	15	15	NUM
cusj-7408	200	9	,	,	PUNCT
cusj-7408	200	10	2021	2021	NUM
cusj-7408	200	11	pinker	pinker	PROPN
cusj-7408	200	12	et	et	PROPN
cusj-7408	200	13	.	.	PUNCT
cusj-7408	201	1	al	al	PROPN
cusj-7408	201	2	.	.	PUNCT
cusj-7408	202	1	[	[	X
cusj-7408	202	2	3	3	X
cusj-7408	202	3	]	]	X
cusj-7408	202	4	sender	sender	NOUN
cusj-7408	202	5	r	r	NOUN
cusj-7408	202	6	,	,	PUNCT
cusj-7408	202	7	fuchs	fuchs	PROPN
cusj-7408	202	8	s	s	PROPN
cusj-7408	202	9	,	,	PUNCT
cusj-7408	202	10	milo	milo	PROPN
cusj-7408	202	11	r.	r.	PROPN
cusj-7408	202	12	revised	revise	VERB
cusj-7408	202	13	estimates	estimate	NOUN
cusj-7408	202	14	for	for	ADP
cusj-7408	202	15	the	the	DET
cusj-7408	202	16	number	number	NOUN
cusj-7408	202	17	of	of	ADP
cusj-7408	202	18	human	human	ADJ
cusj-7408	202	19	and	and	CCONJ
cusj-7408	202	20	bacteria	bacteria	NOUN
cusj-7408	202	21	cells	cell	NOUN
cusj-7408	202	22	in	in	ADP
cusj-7408	202	23	the	the	DET
cusj-7408	202	24	body	body	NOUN
cusj-7408	202	25	.	.	PUNCT
cusj-7408	203	1	plos	plos	PROPN
cusj-7408	203	2	biology	biology	NOUN
cusj-7408	203	3	.	.	PUNCT
cusj-7408	204	1	2016;14(8):e1002533	2016;14(8):e1002533	X
cusj-7408	204	2	.	.	PUNCT
cusj-7408	204	3	doi:10.1371	doi:10.1371	PROPN
cusj-7408	204	4	/	/	SYM
cusj-7408	204	5	journal	journal	NOUN
cusj-7408	204	6	.	.	PUNCT
cusj-7408	205	1	pbio.1002533	pbio.1002533	ADJ
cusj-7408	205	2	.	.	PUNCT
cusj-7408	206	1	[	[	X
cusj-7408	206	2	4	4	NUM
cusj-7408	206	3	]	]	X
cusj-7408	206	4	clemente	clemente	PROPN
cusj-7408	206	5	,	,	PUNCT
cusj-7408	206	6	j.c	j.c	PROPN
cusj-7408	206	7	.	.	PROPN
cusj-7408	206	8	,	,	PUNCT
cusj-7408	206	9	ursell	ursell	PROPN
cusj-7408	206	10	,	,	PUNCT
cusj-7408	206	11	l.k	l.k	PROPN
cusj-7408	206	12	.	.	PROPN
cusj-7408	206	13	,	,	PUNCT
cusj-7408	206	14	parfrey	parfrey	PROPN
cusj-7408	206	15	,	,	PUNCT
cusj-7408	206	16	l.w	l.w	PROPN
cusj-7408	206	17	.	.	PROPN
cusj-7408	206	18	,	,	PUNCT
cusj-7408	206	19	and	and	CCONJ
cusj-7408	206	20	knight	knight	NOUN
cusj-7408	206	21	,	,	PUNCT
cusj-7408	206	22	r.	r.	PROPN
cusj-7408	206	23	(	(	PUNCT
cusj-7408	206	24	2012	2012	NUM
cusj-7408	206	25	)	)	PUNCT
cusj-7408	206	26	.	.	PUNCT
cusj-7408	207	1	the	the	DET
cusj-7408	207	2	impact	impact	NOUN
cusj-7408	207	3	of	of	ADP
cusj-7408	207	4	the	the	DET
cusj-7408	207	5	gut	gut	NOUN
cusj-7408	207	6	microbiota	microbiota	NOUN
cusj-7408	207	7	on	on	ADP
cusj-7408	207	8	human	human	ADJ
cusj-7408	207	9	health	health	NOUN
cusj-7408	207	10	:	:	PUNCT
cusj-7408	207	11	an	an	DET
cusj-7408	207	12	integrative	integrative	ADJ
cusj-7408	207	13	view	view	NOUN
cusj-7408	207	14	.	.	PUNCT
cusj-7408	208	1	cell	cell	NOUN
cusj-7408	209	1	[	[	X
cusj-7408	209	2	5	5	NUM
cusj-7408	209	3	]	]	X
cusj-7408	209	4	sommer	sommer	NOUN
cusj-7408	209	5	,	,	PUNCT
cusj-7408	209	6	f.	f.	PROPN
cusj-7408	209	7	,	,	PUNCT
cusj-7408	209	8	and	and	CCONJ
cusj-7408	209	9	backhed	backhe	VERB
cusj-7408	209	10	,	,	PUNCT
cusj-7408	209	11	f.	f.	PROPN
cusj-7408	209	12	(	(	PUNCT
cusj-7408	209	13	2013	2013	NUM
cusj-7408	209	14	)	)	PUNCT
cusj-7408	209	15	.	.	PUNCT
cusj-7408	210	1	the	the	DET
cusj-7408	210	2	gut	gut	NOUN
cusj-7408	210	3	microbiota	microbiota	NOUN
cusj-7408	210	4	—	—	PUNCT
cusj-7408	210	5	masters	master	NOUN
cusj-7408	210	6	of	of	ADP
cusj-7408	210	7	host	host	NOUN
cusj-7408	210	8	development	development	NOUN
cusj-7408	210	9	and	and	CCONJ
cusj-7408	210	10	physiology	physiology	NOUN
cusj-7408	210	11	.	.	PUNCT
cusj-7408	211	1	nat	nat	PROPN
cusj-7408	211	2	.	.	PUNCT
cusj-7408	212	1	rev	rev	PROPN
cusj-7408	212	2	.	.	PROPN
cusj-7408	212	3	microbiol	microbiol	PROPN
cusj-7408	213	1	[	[	X
cusj-7408	213	2	6	6	NUM
cusj-7408	213	3	]	]	PUNCT
cusj-7408	213	4	hsiao	hsiao	PROPN
cusj-7408	213	5	,	,	PUNCT
cusj-7408	213	6	e.y	e.y	PROPN
cusj-7408	213	7	.	.	PROPN
cusj-7408	213	8	,	,	PUNCT
cusj-7408	213	9	mcbride	mcbride	PROPN
cusj-7408	213	10	,	,	PUNCT
cusj-7408	213	11	s.w	s.w	PROPN
cusj-7408	213	12	.	.	PROPN
cusj-7408	213	13	,	,	PUNCT
cusj-7408	213	14	hsien	hsien	PROPN
cusj-7408	213	15	,	,	PUNCT
cusj-7408	213	16	s.	s.	PROPN
cusj-7408	213	17	,	,	PUNCT
cusj-7408	213	18	sharon	sharon	PROPN
cusj-7408	213	19	,	,	PUNCT
cusj-7408	213	20	g.	g.	PROPN
cusj-7408	213	21	,	,	PUNCT
cusj-7408	213	22	hyde	hyde	PROPN
cusj-7408	213	23	,	,	PUNCT
cusj-7408	213	24	e.r	e.r	PROPN
cusj-7408	213	25	.	.	PROPN
cusj-7408	213	26	,	,	PUNCT
cusj-7408	213	27	mccue	mccue	PROPN
cusj-7408	213	28	,	,	PUNCT
cusj-7408	213	29	t.	t.	PROPN
cusj-7408	213	30	,	,	PUNCT
cusj-7408	213	31	codelli	codelli	PROPN
cusj-7408	213	32	,	,	PUNCT
cusj-7408	213	33	j.a	j.a	PROPN
cusj-7408	213	34	.	.	PROPN
cusj-7408	213	35	,	,	PUNCT
cusj-7408	213	36	chow	chow	PROPN
cusj-7408	213	37	,	,	PUNCT
cusj-7408	213	38	j.	j.	PROPN
cusj-7408	213	39	,	,	PUNCT
cusj-7408	213	40	reisman	reisman	PROPN
cusj-7408	213	41	,	,	PUNCT
cusj-7408	213	42	s.e	s.e	PROPN
cusj-7408	213	43	.	.	PROPN
cusj-7408	213	44	,	,	PUNCT
cusj-7408	213	45	petrosino	petrosino	PROPN
cusj-7408	213	46	,	,	PUNCT
cusj-7408	213	47	j.f	j.f	PROPN
cusj-7408	213	48	.	.	PROPN
cusj-7408	213	49	,	,	PUNCT
cusj-7408	213	50	et	et	PROPN
cusj-7408	213	51	al	al	PROPN
cusj-7408	213	52	.	.	PROPN
cusj-7408	214	1	(	(	PUNCT
cusj-7408	214	2	2013	2013	NUM
cusj-7408	214	3	)	)	PUNCT
cusj-7408	214	4	.	.	PUNCT
cusj-7408	215	1	microbiota	microbiota	NOUN
cusj-7408	215	2	modulate	modulate	VERB
cusj-7408	215	3	behavioral	behavioral	ADJ
cusj-7408	215	4	and	and	CCONJ
cusj-7408	215	5	physiological	physiological	ADJ
cusj-7408	215	6	abnormalities	abnormality	NOUN
cusj-7408	215	7	associated	associate	VERB
cusj-7408	215	8	with	with	ADP
cusj-7408	215	9	neurodevelopmental	neurodevelopmental	ADJ
cusj-7408	215	10	disorders	disorder	NOUN
cusj-7408	215	11	.	.	PUNCT
cusj-7408	216	1	cell	cell	NOUN
cusj-7408	217	1	[	[	X
cusj-7408	217	2	7	7	X
cusj-7408	217	3	]	]	X
cusj-7408	217	4	shi	shi	PROPN
cusj-7408	217	5	n	n	PROPN
cusj-7408	217	6	,	,	PUNCT
cusj-7408	217	7	li	li	PROPN
cusj-7408	217	8	n	n	PROPN
cusj-7408	217	9	,	,	PUNCT
cusj-7408	217	10	duan	duan	PROPN
cusj-7408	217	11	x	x	PROPN
cusj-7408	217	12	,	,	PUNCT
cusj-7408	217	13	niu	niu	PROPN
cusj-7408	217	14	h.	h.	PROPN
cusj-7408	217	15	interaction	interaction	NOUN
cusj-7408	217	16	between	between	ADP
cusj-7408	217	17	the	the	DET
cusj-7408	217	18	gut	gut	NOUN
cusj-7408	217	19	microbiome	microbiome	NOUN
cusj-7408	217	20	and	and	CCONJ
cusj-7408	217	21	mucosal	mucosal	ADJ
cusj-7408	217	22	immune	immune	ADJ
cusj-7408	217	23	system	system	NOUN
cusj-7408	217	24	.	.	PUNCT
cusj-7408	218	1	military	military	ADJ
cusj-7408	218	2	medical	medical	ADJ
cusj-7408	218	3	research	research	NOUN
cusj-7408	218	4	.	.	PUNCT
cusj-7408	219	1	2017;4:14	2017;4:14	PROPN
cusj-7408	219	2	.	.	PUNCT
cusj-7408	220	1	doi:10.1186	doi:10.1186	PROPN
cusj-7408	220	2	/	/	SYM
cusj-7408	220	3	s40779	s40779	PROPN
cusj-7408	220	4	-	-	PUNCT
cusj-7408	220	5	017	017	NUM
cusj-7408	220	6	-	-	PUNCT
cusj-7408	220	7	0122	0122	NUM
cusj-7408	220	8	-	-	SYM
cusj-7408	220	9	9	9	NUM
cusj-7408	220	10	.	.	PUNCT
cusj-7408	221	1	[	[	X
cusj-7408	221	2	8	8	NUM
cusj-7408	221	3	]	]	PUNCT
cusj-7408	221	4	thaiss	thaiss	NOUN
cusj-7408	221	5	c.a	c.a	PROPN
cusj-7408	221	6	.	.	PROPN
cusj-7408	221	7	,	,	PUNCT
cusj-7408	221	8	zeevi	zeevi	PROPN
cusj-7408	221	9	d.	d.	PROPN
cusj-7408	221	10	,	,	PUNCT
cusj-7408	221	11	levy	levy	NOUN
cusj-7408	221	12	m.	m.	NOUN
cusj-7408	221	13	,	,	PUNCT
cusj-7408	221	14	zilberman	zilberman	NOUN
cusj-7408	221	15	-	-	PUNCT
cusj-7408	221	16	schapira	schapira	PROPN
cusj-7408	221	17	g.	g.	PROPN
cusj-7408	221	18	,	,	PUNCT
cusj-7408	221	19	suez	suez	PROPN
cusj-7408	221	20	j.	j.	PROPN
cusj-7408	221	21	,	,	PUNCT
cusj-7408	221	22	tengeler	tengeler	PROPN
cusj-7408	221	23	a.c	a.c	PROPN
cusj-7408	221	24	.	.	PROPN
cusj-7408	221	25	transkingdom	transkingdom	NOUN
cusj-7408	221	26	control	control	NOUN
cusj-7408	221	27	of	of	ADP
cusj-7408	221	28	microbiota	microbiota	ADJ
cusj-7408	221	29	diurnal	diurnal	ADJ
cusj-7408	221	30	oscillations	oscillation	NOUN
cusj-7408	221	31	promotes	promote	VERB
cusj-7408	221	32	metabolic	metabolic	NOUN
cusj-7408	221	33	homeostasis	homeostasis	NOUN
cusj-7408	221	34	.	.	PUNCT
cusj-7408	222	1	cell	cell	NOUN
cusj-7408	222	2	.	.	PUNCT
cusj-7408	223	1	2014;159(3):514–529	2014;159(3):514–529	NUM
cusj-7408	223	2	[	[	SYM
cusj-7408	223	3	9	9	NUM
cusj-7408	223	4	]	]	X
cusj-7408	223	5	de	de	X
cusj-7408	223	6	groot	groot	X
cusj-7408	223	7	pf	pf	PROPN
cusj-7408	223	8	,	,	PUNCT
cusj-7408	223	9	frissen	frissen	PROPN
cusj-7408	223	10	mn	mn	PROPN
cusj-7408	223	11	,	,	PUNCT
cusj-7408	223	12	de	de	PROPN
cusj-7408	223	13	clercq	clercq	PROPN
cusj-7408	223	14	nc	nc	PROPN
cusj-7408	223	15	,	,	PUNCT
cusj-7408	223	16	nieuwdorp	nieuwdorp	PROPN
cusj-7408	223	17	m.	m.	NOUN
cusj-7408	223	18	fecal	fecal	ADJ
cusj-7408	223	19	microbiota	microbiota	NOUN
cusj-7408	223	20	transplantation	transplantation	NOUN
cusj-7408	223	21	in	in	ADP
cusj-7408	223	22	metabolic	metabolic	NOUN
cusj-7408	223	23	syndrome	syndrome	NOUN
cusj-7408	223	24	:	:	PUNCT
cusj-7408	223	25	history	history	NOUN
cusj-7408	223	26	,	,	PUNCT
cusj-7408	223	27	present	present	ADJ
cusj-7408	223	28	and	and	CCONJ
cusj-7408	223	29	future	future	ADJ
cusj-7408	223	30	.	.	PUNCT
cusj-7408	224	1	gut	gut	NOUN
cusj-7408	224	2	microbes	microbe	NOUN
cusj-7408	224	3	(	(	PUNCT
cusj-7408	224	4	2017	2017	NUM
cusj-7408	224	5	)	)	PUNCT
cusj-7408	225	1	[	[	X
cusj-7408	225	2	10	10	NUM
cusj-7408	225	3	]	]	SYM
cusj-7408	225	4	dibner	dibner	NOUN
cusj-7408	225	5	,	,	PUNCT
cusj-7408	225	6	c.	c.	PROPN
cusj-7408	225	7	,	,	PUNCT
cusj-7408	225	8	schibler	schibler	NOUN
cusj-7408	225	9	,	,	PUNCT
cusj-7408	225	10	u.	u.	PROPN
cusj-7408	225	11	,	,	PUNCT
cusj-7408	225	12	and	and	CCONJ
cusj-7408	225	13	albrecht	albrecht	PROPN
cusj-7408	225	14	,	,	PUNCT
cusj-7408	225	15	u.	u.	PROPN
cusj-7408	225	16	(	(	PUNCT
cusj-7408	225	17	2010	2010	NUM
cusj-7408	225	18	)	)	PUNCT
cusj-7408	225	19	.	.	PUNCT
cusj-7408	226	1	the	the	DET
cusj-7408	226	2	mammalian	mammalian	ADJ
cusj-7408	226	3	circadian	circadian	ADJ
cusj-7408	226	4	timing	timing	NOUN
cusj-7408	226	5	system	system	NOUN
cusj-7408	226	6	:	:	PUNCT
cusj-7408	226	7	organization	organization	NOUN
cusj-7408	226	8	and	and	CCONJ
cusj-7408	226	9	coordination	coordination	NOUN
cusj-7408	226	10	of	of	ADP
cusj-7408	226	11	central	central	ADJ
cusj-7408	226	12	and	and	CCONJ
cusj-7408	226	13	peripheral	peripheral	ADJ
cusj-7408	226	14	clocks	clock	NOUN
cusj-7408	226	15	.	.	PUNCT
cusj-7408	227	1	annu	annu	NOUN
cusj-7408	227	2	.	.	PUNCT
cusj-7408	228	1	rev	rev	PROPN
cusj-7408	228	2	.	.	PROPN
cusj-7408	228	3	physiol	physiol	PROPN
cusj-7408	228	4	.	.	PUNCT
cusj-7408	229	1	[	[	X
cusj-7408	229	2	11	11	NUM
cusj-7408	229	3	]	]	X
cusj-7408	229	4	keller	keller	PROPN
cusj-7408	229	5	,	,	PUNCT
cusj-7408	229	6	m.	m.	NOUN
cusj-7408	229	7	,	,	PUNCT
cusj-7408	229	8	mazuch	mazuch	PROPN
cusj-7408	229	9	,	,	PUNCT
cusj-7408	229	10	j.	j.	PROPN
cusj-7408	229	11	,	,	PUNCT
cusj-7408	229	12	abraham	abraham	PROPN
cusj-7408	229	13	,	,	PUNCT
cusj-7408	229	14	u.	u.	PROPN
cusj-7408	229	15	,	,	PUNCT
cusj-7408	229	16	eom	eom	PROPN
cusj-7408	229	17	,	,	PUNCT
cusj-7408	229	18	g.d	g.d	PROPN
cusj-7408	229	19	.	.	PROPN
cusj-7408	229	20	,	,	PUNCT
cusj-7408	229	21	herzog	herzog	PROPN
cusj-7408	229	22	,	,	PUNCT
cusj-7408	229	23	e.d	e.d	PROPN
cusj-7408	229	24	.	.	PROPN
cusj-7408	229	25	,	,	PUNCT
cusj-7408	229	26	volk	volk	PROPN
cusj-7408	229	27	,	,	PUNCT
cusj-7408	229	28	h.d	h.d	PROPN
cusj-7408	229	29	.	.	PROPN
cusj-7408	229	30	,	,	PUNCT
cusj-7408	229	31	kramer	kramer	PROPN
cusj-7408	229	32	,	,	PUNCT
cusj-7408	229	33	a.	a.	PROPN
cusj-7408	229	34	,	,	PUNCT
cusj-7408	229	35	and	and	CCONJ
cusj-7408	229	36	maier	maier	PROPN
cusj-7408	229	37	,	,	PUNCT
cusj-7408	229	38	b.	b.	PROPN
cusj-7408	229	39	(	(	PUNCT
cusj-7408	229	40	2009	2009	NUM
cusj-7408	229	41	)	)	PUNCT
cusj-7408	229	42	.	.	PUNCT
cusj-7408	230	1	a	a	DET
cusj-7408	230	2	circadian	circadian	ADJ
cusj-7408	230	3	clock	clock	NOUN
cusj-7408	230	4	in	in	ADP
cusj-7408	230	5	macrophages	macrophage	NOUN
cusj-7408	230	6	controls	control	VERB
cusj-7408	230	7	inflammatory	inflammatory	ADJ
cusj-7408	230	8	immune	immune	ADJ
cusj-7408	230	9	responses	response	NOUN
cusj-7408	230	10	.	.	PUNCT
cusj-7408	231	1	proc	proc	NOUN
cusj-7408	231	2	.	.	PUNCT
cusj-7408	232	1	natl	natl	PROPN
cusj-7408	232	2	.	.	PUNCT
cusj-7408	233	1	acad	acad	PROPN
cusj-7408	233	2	.	.	PUNCT
cusj-7408	234	1	sci	sci	PROPN
cusj-7408	234	2	.	.	PUNCT
cusj-7408	235	1	[	[	X
cusj-7408	235	2	12	12	NUM
cusj-7408	235	3	]	]	PUNCT
cusj-7408	235	4	takahashi	takahashi	PROPN
cusj-7408	235	5	js	js	PROPN
cusj-7408	235	6	.	.	PUNCT
cusj-7408	235	7	transcriptional	transcriptional	ADJ
cusj-7408	235	8	architecture	architecture	NOUN
cusj-7408	235	9	of	of	ADP
cusj-7408	235	10	the	the	DET
cusj-7408	235	11	mammalian	mammalian	ADJ
cusj-7408	235	12	circadian	circadian	ADJ
cusj-7408	235	13	clock	clock	NOUN
cusj-7408	235	14	.	.	PUNCT
cusj-7408	236	1	nature	nature	NOUN
cusj-7408	236	2	reviews	review	VERB
cusj-7408	236	3	genetics	genetic	NOUN
cusj-7408	236	4	.	.	PUNCT
cusj-7408	237	1	2017;18(3):164	2017;18(3):164	NUM
cusj-7408	237	2	-	-	SYM
cusj-7408	237	3	179	179	NUM
cusj-7408	237	4	.	.	PUNCT
cusj-7408	238	1	doi:10.1038	doi:10.1038	NOUN
cusj-7408	238	2	/	/	SYM
cusj-7408	238	3	nrg.2016.150	nrg.2016.150	PROPN
cusj-7408	238	4	.	.	PUNCT
cusj-7408	239	1	[	[	X
cusj-7408	239	2	13	13	NUM
cusj-7408	239	3	]	]	X
cusj-7408	239	4	buxton	buxton	PROPN
cusj-7408	239	5	,	,	PUNCT
cusj-7408	239	6	o.m	o.m	PROPN
cusj-7408	239	7	.	.	PROPN
cusj-7408	239	8	,	,	PUNCT
cusj-7408	239	9	cain	cain	PROPN
cusj-7408	239	10	,	,	PUNCT
cusj-7408	239	11	s.w	s.w	PROPN
cusj-7408	239	12	.	.	PROPN
cusj-7408	239	13	,	,	PUNCT
cusj-7408	239	14	o’connor	o’connor	ADV
cusj-7408	239	15	,	,	PUNCT
cusj-7408	239	16	s.p	s.p	PROPN
cusj-7408	239	17	.	.	PROPN
cusj-7408	239	18	,	,	PUNCT
cusj-7408	239	19	porter	porter	PROPN
cusj-7408	239	20	,	,	PUNCT
cusj-7408	239	21	j.h	j.h	PROPN
cusj-7408	239	22	.	.	PROPN
cusj-7408	239	23	,	,	PUNCT
cusj-7408	239	24	duffy	duffy	PROPN
cusj-7408	239	25	,	,	PUNCT
cusj-7408	239	26	j.f	j.f	PROPN
cusj-7408	239	27	.	.	PROPN
cusj-7408	239	28	,	,	PUNCT
cusj-7408	239	29	wang	wang	PROPN
cusj-7408	239	30	,	,	PUNCT
cusj-7408	239	31	w.	w.	PROPN
cusj-7408	239	32	,	,	PUNCT
cusj-7408	239	33	czeisler	czeisler	PROPN
cusj-7408	239	34	,	,	PUNCT
cusj-7408	239	35	c.a	c.a	PROPN
cusj-7408	239	36	.	.	PROPN
cusj-7408	239	37	,	,	PUNCT
cusj-7408	239	38	and	and	CCONJ
cusj-7408	239	39	shea	shea	PROPN
cusj-7408	239	40	,	,	PUNCT
cusj-7408	239	41	s.a	s.a	PROPN
cusj-7408	239	42	.	.	PROPN
cusj-7408	239	43	(	(	PUNCT
cusj-7408	239	44	2012	2012	NUM
cusj-7408	239	45	)	)	PUNCT
cusj-7408	239	46	.	.	PUNCT
cusj-7408	240	1	adverse	adverse	ADJ
cusj-7408	240	2	metabolic	metabolic	NOUN
cusj-7408	240	3	consequences	consequence	NOUN
cusj-7408	240	4	in	in	ADP
cusj-7408	240	5	humans	human	NOUN
cusj-7408	240	6	of	of	ADP
cusj-7408	240	7	prolonged	prolonged	ADJ
cusj-7408	240	8	sleep	sleep	NOUN
cusj-7408	240	9	restriction	restriction	NOUN
cusj-7408	240	10	combined	combine	VERB
cusj-7408	240	11	with	with	ADP
cusj-7408	240	12	circadian	circadian	ADJ
cusj-7408	240	13	disruption	disruption	NOUN
cusj-7408	240	14	.	.	PUNCT
cusj-7408	241	1	sci	sci	PROPN
cusj-7408	241	2	.	.	PROPN
cusj-7408	241	3	transl	transl	PROPN
cusj-7408	241	4	.	.	PUNCT
cusj-7408	242	1	med	med	PROPN
cusj-7408	243	1	[	[	X
cusj-7408	243	2	14	14	NUM
cusj-7408	243	3	]	]	X
cusj-7408	243	4	fonken	fonken	VERB
cusj-7408	243	5	,	,	PUNCT
cusj-7408	243	6	l.k	l.k	PROPN
cusj-7408	243	7	.	.	PROPN
cusj-7408	243	8	,	,	PUNCT
cusj-7408	243	9	workman	workman	PROPN
cusj-7408	243	10	,	,	PUNCT
cusj-7408	243	11	j.l	j.l	PROPN
cusj-7408	243	12	.	.	PROPN
cusj-7408	243	13	,	,	PUNCT
cusj-7408	243	14	walton	walton	PROPN
cusj-7408	243	15	,	,	PUNCT
cusj-7408	243	16	j.c	j.c	PROPN
cusj-7408	243	17	.	.	PROPN
cusj-7408	243	18	,	,	PUNCT
cusj-7408	243	19	weil	weil	PROPN
cusj-7408	243	20	,	,	PUNCT
cusj-7408	243	21	z.m	z.m	PROPN
cusj-7408	243	22	.	.	PROPN
cusj-7408	243	23	,	,	PUNCT
cusj-7408	243	24	morris	morris	PROPN
cusj-7408	243	25	,	,	PUNCT
cusj-7408	243	26	j.s	j.s	PROPN
cusj-7408	243	27	.	.	PROPN
cusj-7408	243	28	,	,	PUNCT
cusj-7408	243	29	haim	haim	PROPN
cusj-7408	243	30	,	,	PUNCT
cusj-7408	243	31	a.	a.	NOUN
cusj-7408	243	32	,	,	PUNCT
cusj-7408	243	33	and	and	CCONJ
cusj-7408	243	34	nelson	nelson	PROPN
cusj-7408	243	35	,	,	PUNCT
cusj-7408	243	36	r.j	r.j	PROPN
cusj-7408	243	37	.	.	PROPN
cusj-7408	243	38	(	(	PUNCT
cusj-7408	243	39	2010	2010	NUM
cusj-7408	243	40	)	)	PUNCT
cusj-7408	243	41	.	.	PUNCT
cusj-7408	244	1	light	light	NOUN
cusj-7408	244	2	at	at	ADP
cusj-7408	244	3	night	night	NOUN
cusj-7408	244	4	increases	increase	VERB
cusj-7408	244	5	body	body	NOUN
cusj-7408	244	6	mass	mass	NOUN
cusj-7408	244	7	by	by	ADP
cusj-7408	244	8	shifting	shift	VERB
cusj-7408	244	9	the	the	DET
cusj-7408	244	10	time	time	NOUN
cusj-7408	244	11	of	of	ADP
cusj-7408	244	12	food	food	NOUN
cusj-7408	244	13	intake	intake	NOUN
cusj-7408	244	14	.	.	PUNCT
cusj-7408	245	1	proc	proc	PROPN
cusj-7408	245	2	.	.	PUNCT
cusj-7408	246	1	natl	natl	PROPN
cusj-7408	246	2	.	.	PUNCT
cusj-7408	247	1	acad	acad	PROPN
cusj-7408	247	2	.	.	PUNCT
cusj-7408	248	1	sc	sc	PROPN
cusj-7408	249	1	[	[	X
cusj-7408	249	2	15	15	NUM
cusj-7408	249	3	]	]	X
cusj-7408	249	4	savvidis	savvidis	NOUN
cusj-7408	249	5	c	c	NOUN
cusj-7408	249	6	,	,	PUNCT
cusj-7408	249	7	koutsilieris	koutsilieris	PROPN
cusj-7408	249	8	m.	m.	NOUN
cusj-7408	249	9	circadian	circadian	PROPN
cusj-7408	249	10	rhythm	rhythm	PROPN
cusj-7408	249	11	disruption	disruption	NOUN
cusj-7408	249	12	in	in	ADP
cusj-7408	249	13	cancer	cancer	NOUN
cusj-7408	249	14	biology	biology	NOUN
cusj-7408	249	15	.	.	PUNCT
cusj-7408	250	1	molecular	molecular	ADJ
cusj-7408	250	2	medicine	medicine	NOUN
cusj-7408	250	3	.	.	PUNCT
cusj-7408	251	1	2012;18(1):1249	2012;18(1):1249	NUM
cusj-7408	251	2	-	-	SYM
cusj-7408	251	3	1260	1260	NUM
cusj-7408	251	4	.	.	PUNCT
cusj-7408	252	1	doi:10.2119	doi:10.2119	PROPN
cusj-7408	252	2	/	/	SYM
cusj-7408	252	3	molmed.2012.00077	molmed.2012.00077	PROPN
cusj-7408	252	4	.	.	PUNCT
cusj-7408	253	1	[	[	X
cusj-7408	253	2	16	16	NUM
cusj-7408	253	3	]	]	X
cusj-7408	253	4	scheer	scheer	PROPN
cusj-7408	253	5	,	,	PUNCT
cusj-7408	253	6	f.a	f.a	PROPN
cusj-7408	253	7	.	.	PROPN
cusj-7408	253	8	,	,	PUNCT
cusj-7408	253	9	hilton	hilton	PROPN
cusj-7408	253	10	,	,	PUNCT
cusj-7408	253	11	m.f	m.f	PROPN
cusj-7408	253	12	.	.	PROPN
cusj-7408	253	13	,	,	PUNCT
cusj-7408	253	14	mantzoros	mantzoros	PROPN
cusj-7408	253	15	,	,	PUNCT
cusj-7408	253	16	c.s	c.s	PROPN
cusj-7408	253	17	.	.	PROPN
cusj-7408	253	18	,	,	PUNCT
cusj-7408	253	19	and	and	CCONJ
cusj-7408	253	20	shea	shea	PROPN
cusj-7408	253	21	,	,	PUNCT
cusj-7408	253	22	s.a	s.a	PROPN
cusj-7408	253	23	.	.	PROPN
cusj-7408	253	24	(	(	PUNCT
cusj-7408	253	25	2009	2009	NUM
cusj-7408	253	26	)	)	PUNCT
cusj-7408	253	27	.	.	PUNCT
cusj-7408	254	1	adverse	adverse	ADJ
cusj-7408	254	2	metabolic	metabolic	NOUN
cusj-7408	254	3	and	and	CCONJ
cusj-7408	254	4	cardiovascular	cardiovascular	ADJ
cusj-7408	254	5	consequences	consequence	NOUN
cusj-7408	254	6	of	of	ADP
cusj-7408	254	7	circadian	circadian	ADJ
cusj-7408	254	8	misalignment	misalignment	NOUN
cusj-7408	254	9	.	.	PUNCT
cusj-7408	255	1	proc	proc	PROPN
cusj-7408	255	2	.	.	PUNCT
cusj-7408	256	1	natl	natl	PROPN
cusj-7408	256	2	.	.	PUNCT
cusj-7408	257	1	acad	acad	PROPN
cusj-7408	257	2	.	.	PUNCT
cusj-7408	258	1	sci	sci	PROPN
cusj-7408	259	1	[	[	X
cusj-7408	259	2	17	17	NUM
cusj-7408	259	3	]	]	X
cusj-7408	259	4	swanson	swanson	PROPN
cusj-7408	259	5	,	,	PUNCT
cusj-7408	259	6	gr	gr	PROPN
cusj-7408	259	7	.	.	PROPN
cusj-7408	259	8	,	,	PUNCT
cusj-7408	259	9	burgess	burgess	PROPN
cusj-7408	259	10	,	,	PUNCT
cusj-7408	259	11	hj	hj	PROPN
cusj-7408	259	12	.	.	PROPN
cusj-7408	259	13	(	(	PUNCT
cusj-7408	259	14	2017	2017	NUM
cusj-7408	259	15	)	)	PUNCT
cusj-7408	259	16	.	.	PUNCT
cusj-7408	260	1	sleep	sleep	NOUN
cusj-7408	260	2	and	and	CCONJ
cusj-7408	260	3	circadian	circadian	ADJ
cusj-7408	260	4	hygiene	hygiene	NOUN
cusj-7408	260	5	and	and	CCONJ
cusj-7408	260	6	inflammatory	inflammatory	ADJ
cusj-7408	260	7	bowel	bowel	NOUN
cusj-7408	260	8	disease	disease	NOUN
cusj-7408	260	9	.	.	PUNCT
cusj-7408	261	1	gastroenterology	gastroenterology	NOUN
cusj-7408	261	2	clinics	clinic	NOUN
cusj-7408	261	3	of	of	ADP
cusj-7408	261	4	north	north	NOUN
cusj-7408	261	5	america.46(4):881893	america.46(4):881893	NOUN
cusj-7408	261	6	.	.	PUNCT
cusj-7408	262	1	doi:10.1016	doi:10.1016	PROPN
cusj-7408	262	2	/	/	SYM
cusj-7408	262	3	j.gtc.2017.08.014	j.gtc.2017.08.014	PROPN
cusj-7408	263	1	[	[	X
cusj-7408	263	2	18	18	NUM
cusj-7408	263	3	]	]	X
cusj-7408	263	4	koch	koch	PROPN
cusj-7408	263	5	s	s	PROPN
cusj-7408	263	6	,	,	PUNCT
cusj-7408	263	7	nusrat	nusrat	PROPN
cusj-7408	263	8	a.	a.	NOUN
cusj-7408	263	9	the	the	DET
cusj-7408	263	10	life	life	NOUN
cusj-7408	263	11	and	and	CCONJ
cusj-7408	263	12	death	death	NOUN
cusj-7408	263	13	of	of	ADP
cusj-7408	263	14	epithelia	epithelium	NOUN
cusj-7408	263	15	during	during	ADP
cusj-7408	263	16	inflammation	inflammation	NOUN
cusj-7408	263	17	:	:	PUNCT
cusj-7408	263	18	lessons	lesson	NOUN
cusj-7408	263	19	learned	learn	VERB
cusj-7408	263	20	from	from	ADP
cusj-7408	263	21	the	the	DET
cusj-7408	263	22	gut	gut	PROPN
cusj-7408	263	23	.	.	PUNCT
cusj-7408	264	1	ann	ann	PROPN
cusj-7408	264	2	.	.	PUNCT
cusj-7408	265	1	rev	rev	PROPN
cusj-7408	265	2	.	.	PROPN
cusj-7408	265	3	pathol	pathol	PROPN
cusj-7408	265	4	.	.	PUNCT
cusj-7408	266	1	2012;7:35–60	2012;7:35–60	X
cusj-7408	266	2	.	.	PUNCT
cusj-7408	266	3	doi	doi	NOUN
cusj-7408	266	4	:	:	PUNCT
cusj-7408	266	5	10.1146	10.1146	NUM
cusj-7408	266	6	/	/	SYM
cusj-7408	266	7	annurev	annurev	ADJ
cusj-7408	266	8	-	-	PUNCT
cusj-7408	266	9	pathol-011811	pathol-011811	ADJ
cusj-7408	266	10	-	-	PUNCT
cusj-7408	266	11	120905	120905	NUM
cusj-7408	266	12	.	.	PUNCT
cusj-7408	267	1	[	[	X
cusj-7408	267	2	19	19	NUM
cusj-7408	267	3	]	]	X
cusj-7408	267	4	groschwitz	groschwitz	PROPN
cusj-7408	267	5	kr	kr	PROPN
cusj-7408	267	6	,	,	PUNCT
cusj-7408	267	7	hogan	hogan	PROPN
cusj-7408	267	8	sp	sp	PROPN
cusj-7408	267	9	.	.	PUNCT
cusj-7408	267	10	intestinal	intestinal	ADJ
cusj-7408	267	11	barrier	barrier	NOUN
cusj-7408	267	12	function	function	NOUN
cusj-7408	267	13	:	:	PUNCT
cusj-7408	267	14	molecular	molecular	ADJ
cusj-7408	267	15	regulation	regulation	NOUN
cusj-7408	267	16	and	and	CCONJ
cusj-7408	267	17	disease	disease	NOUN
cusj-7408	267	18	pathogenesis	pathogenesis	NOUN
cusj-7408	267	19	.	.	PUNCT
cusj-7408	268	1	the	the	DET
cusj-7408	268	2	journal	journal	PROPN
cusj-7408	268	3	of	of	ADP
cusj-7408	268	4	allergy	allergy	NOUN
cusj-7408	268	5	and	and	CCONJ
cusj-7408	268	6	clinical	clinical	ADJ
cusj-7408	268	7	immunology	immunology	NOUN
cusj-7408	268	8	.	.	PUNCT
cusj-7408	269	1	2009;124(1):3	2009;124(1):3	NUM
cusj-7408	269	2	-	-	SYM
cusj-7408	269	3	22	22	NUM
cusj-7408	269	4	.	.	NOUN
cusj-7408	269	5	15	15	NUM
cusj-7408	269	6	columbia	columbia	PROPN
cusj-7408	269	7	undergraduate	undergraduate	PROPN
cusj-7408	269	8	science	science	PROPN
cusj-7408	269	9	journal	journal	PROPN
cusj-7408	269	10	vol	vol	NOUN
cusj-7408	269	11	.	.	PROPN
cusj-7408	269	12	15	15	NUM
cusj-7408	269	13	,	,	PUNCT
cusj-7408	269	14	2021	2021	NUM
cusj-7408	269	15	pinker	pinker	PROPN
cusj-7408	269	16	et	et	PROPN
cusj-7408	269	17	.	.	PUNCT
cusj-7408	270	1	al	al	PROPN
cusj-7408	270	2	.	.	PROPN
cusj-7408	270	3	doi:10.1016	doi:10.1016	PROPN
cusj-7408	270	4	/	/	SYM
cusj-7408	270	5	j.jaci.2009.05.038	j.jaci.2009.05.038	PROPN
cusj-7408	270	6	.	.	PUNCT
cusj-7408	271	1	[	[	X
cusj-7408	271	2	20	20	NUM
cusj-7408	271	3	]	]	X
cusj-7408	271	4	mu	mu	PROPN
cusj-7408	271	5	q	q	PROPN
cusj-7408	271	6	,	,	PUNCT
cusj-7408	271	7	kirby	kirby	PROPN
cusj-7408	271	8	j	j	PROPN
cusj-7408	271	9	,	,	PUNCT
cusj-7408	271	10	reilly	reilly	PROPN
cusj-7408	271	11	cm	cm	PROPN
cusj-7408	271	12	,	,	PUNCT
cusj-7408	271	13	luo	luo	PROPN
cusj-7408	271	14	xm	xm	PROPN
cusj-7408	271	15	.	.	PUNCT
cusj-7408	272	1	leaky	leaky	PROPN
cusj-7408	272	2	gut	gut	VERB
cusj-7408	272	3	as	as	ADP
cusj-7408	272	4	a	a	DET
cusj-7408	272	5	danger	danger	NOUN
cusj-7408	272	6	signal	signal	NOUN
cusj-7408	272	7	for	for	ADP
cusj-7408	272	8	autoimmune	autoimmune	ADJ
cusj-7408	272	9	diseases	disease	NOUN
cusj-7408	272	10	.	.	PUNCT
cusj-7408	273	1	frontiers	frontier	NOUN
cusj-7408	273	2	in	in	ADP
cusj-7408	273	3	immunology	immunology	NOUN
cusj-7408	273	4	.	.	PUNCT
cusj-7408	274	1	2017;8:598	2017;8:598	NUM
cusj-7408	274	2	.	.	PUNCT
cusj-7408	274	3	doi:10.3389	doi:10.3389	PROPN
cusj-7408	274	4	/	/	SYM
cusj-7408	274	5	fimmu.2017.00598	fimmu.2017.00598	NOUN
cusj-7408	274	6	.	.	PUNCT
cusj-7408	275	1	[	[	X
cusj-7408	275	2	21	21	NUM
cusj-7408	275	3	]	]	X
cusj-7408	275	4	kiela	kiela	PROPN
cusj-7408	275	5	pr	pr	PROPN
cusj-7408	275	6	,	,	PUNCT
cusj-7408	275	7	ghishan	ghishan	PROPN
cusj-7408	275	8	fk	fk	INTJ
cusj-7408	275	9	.	.	PUNCT
cusj-7408	275	10	physiology	physiology	NOUN
cusj-7408	275	11	of	of	ADP
cusj-7408	275	12	intestinal	intestinal	ADJ
cusj-7408	275	13	absorption	absorption	NOUN
cusj-7408	275	14	and	and	CCONJ
cusj-7408	275	15	secretion	secretion	NOUN
cusj-7408	275	16	.	.	PUNCT
cusj-7408	276	1	best	good	ADJ
cusj-7408	276	2	practice	practice	PROPN
cusj-7408	276	3	&	&	CCONJ
cusj-7408	276	4	research	research	NOUN
cusj-7408	276	5	clinical	clinical	ADJ
cusj-7408	276	6	gastroenterology	gastroenterology	NOUN
cusj-7408	276	7	.	.	PUNCT
cusj-7408	277	1	2016;30(2):145	2016;30(2):145	NUM
cusj-7408	277	2	-	-	SYM
cusj-7408	277	3	159	159	NUM
cusj-7408	277	4	.	.	PUNCT
cusj-7408	277	5	doi:10.1016	doi:10.1016	PROPN
cusj-7408	277	6	/	/	SYM
cusj-7408	277	7	j.	j.	PROPN
cusj-7408	277	8	bpg.2016.02.007	bpg.2016.02.007	PROPN
cusj-7408	277	9	.	.	PUNCT
cusj-7408	278	1	[	[	X
cusj-7408	278	2	22	22	NUM
cusj-7408	278	3	]	]	X
cusj-7408	278	4	chakaroun	chakaroun	PROPN
cusj-7408	278	5	rm	rm	PROPN
cusj-7408	278	6	,	,	PUNCT
cusj-7408	278	7	massier	massier	PROPN
cusj-7408	278	8	l	l	PROPN
cusj-7408	278	9	,	,	PUNCT
cusj-7408	278	10	kovacs	kovacs	PROPN
cusj-7408	278	11	p.	p.	PROPN
cusj-7408	278	12	gut	gut	NOUN
cusj-7408	278	13	microbiome	microbiome	NOUN
cusj-7408	278	14	,	,	PUNCT
cusj-7408	278	15	intestinal	intestinal	ADJ
cusj-7408	278	16	permeability	permeability	NOUN
cusj-7408	278	17	,	,	PUNCT
cusj-7408	278	18	and	and	CCONJ
cusj-7408	278	19	tissue	tissue	NOUN
cusj-7408	278	20	bacteria	bacteria	NOUN
cusj-7408	278	21	in	in	ADP
cusj-7408	278	22	metabolic	metabolic	NOUN
cusj-7408	278	23	disease	disease	NOUN
cusj-7408	278	24	:	:	PUNCT
cusj-7408	278	25	perpetrators	perpetrator	NOUN
cusj-7408	278	26	or	or	CCONJ
cusj-7408	278	27	bystanders	bystander	NOUN
cusj-7408	278	28	?	?	PUNCT
cusj-7408	279	1	nutrients	nutrient	NOUN
cusj-7408	279	2	.	.	PUNCT
cusj-7408	280	1	2020;12(4	2020;12(4	NUM
cusj-7408	280	2	)	)	PUNCT
cusj-7408	280	3	.	.	PUNCT
cusj-7408	281	1	doi:10.3390	doi:10.3390	NOUN
cusj-7408	281	2	/	/	SYM
cusj-7408	281	3	nu12041082	nu12041082	PROPN
cusj-7408	282	1	[	[	X
cusj-7408	282	2	23	23	NUM
cusj-7408	282	3	]	]	X
cusj-7408	282	4	archer	archer	PROPN
cusj-7408	282	5	,	,	PUNCT
cusj-7408	282	6	s.n	s.n	PROPN
cusj-7408	282	7	.	.	PROPN
cusj-7408	282	8	,	,	PUNCT
cusj-7408	282	9	laing	laing	PROPN
cusj-7408	282	10	,	,	PUNCT
cusj-7408	282	11	e.e	e.e	PROPN
cusj-7408	282	12	.	.	PROPN
cusj-7408	282	13	,	,	PUNCT
cusj-7408	282	14	mo¨	mo¨	ADJ
cusj-7408	282	15	ller	ller	NOUN
cusj-7408	282	16	-	-	PUNCT
cusj-7408	282	17	levet	levet	NOUN
cusj-7408	282	18	,	,	PUNCT
cusj-7408	282	19	c.s	c.s	PROPN
cusj-7408	282	20	.	.	PROPN
cusj-7408	282	21	,	,	PUNCT
cusj-7408	282	22	van	van	PROPN
cusj-7408	282	23	der	der	PROPN
cusj-7408	282	24	veen	veen	PROPN
cusj-7408	282	25	,	,	PUNCT
cusj-7408	282	26	d.r	d.r	PROPN
cusj-7408	282	27	.	.	PROPN
cusj-7408	282	28	,	,	PUNCT
cusj-7408	282	29	bucca	bucca	PROPN
cusj-7408	282	30	,	,	PUNCT
cusj-7408	282	31	g.	g.	PROPN
cusj-7408	282	32	,	,	PUNCT
cusj-7408	282	33	lazar	lazar	PROPN
cusj-7408	282	34	,	,	PUNCT
cusj-7408	282	35	a.s	a.s	PROPN
cusj-7408	282	36	.	.	PROPN
cusj-7408	282	37	,	,	PUNCT
cusj-7408	282	38	santhi	santhi	ADJ
cusj-7408	282	39	,	,	PUNCT
cusj-7408	282	40	n.	n.	NOUN
cusj-7408	282	41	,	,	PUNCT
cusj-7408	282	42	slak	slak	NOUN
cusj-7408	282	43	,	,	PUNCT
cusj-7408	282	44	a.	a.	NOUN
cusj-7408	282	45	,	,	PUNCT
cusj-7408	282	46	kabiljo	kabiljo	PROPN
cusj-7408	282	47	,	,	PUNCT
cusj-7408	282	48	r.	r.	PROPN
cusj-7408	282	49	,	,	PUNCT
cusj-7408	282	50	von	von	PROPN
cusj-7408	282	51	schantz	schantz	PROPN
cusj-7408	282	52	,	,	PUNCT
cusj-7408	282	53	m.	m.	NOUN
cusj-7408	282	54	,	,	PUNCT
cusj-7408	282	55	et	et	PROPN
cusj-7408	282	56	al	al	PROPN
cusj-7408	282	57	.	.	PUNCT
cusj-7408	283	1	(	(	PUNCT
cusj-7408	283	2	2014	2014	NUM
cusj-7408	283	3	)	)	PUNCT
cusj-7408	283	4	.	.	PUNCT
cusj-7408	284	1	mistimed	mistimed	ADJ
cusj-7408	284	2	sleep	sleep	NOUN
cusj-7408	284	3	disrupts	disrupt	VERB
cusj-7408	284	4	circadian	circadian	ADJ
cusj-7408	284	5	regulation	regulation	NOUN
cusj-7408	284	6	of	of	ADP
cusj-7408	284	7	the	the	DET
cusj-7408	284	8	human	human	ADJ
cusj-7408	284	9	transcriptome	transcriptome	PROPN
cusj-7408	284	10	.	.	PUNCT
cusj-7408	285	1	proc	proc	PROPN
cusj-7408	285	2	.	.	PUNCT
cusj-7408	286	1	natl	natl	PROPN
cusj-7408	286	2	.	.	PUNCT
cusj-7408	287	1	acad	acad	PROPN
cusj-7408	287	2	.	.	PUNCT
cusj-7408	288	1	sci	sci	PROPN
cusj-7408	289	1	[	[	X
cusj-7408	289	2	24	24	NUM
cusj-7408	289	3	]	]	PUNCT
cusj-7408	289	4	suwazono	suwazono	X
cusj-7408	289	5	,	,	PUNCT
cusj-7408	289	6	y.	y.	PROPN
cusj-7408	289	7	,	,	PUNCT
cusj-7408	289	8	dochi	dochi	PROPN
cusj-7408	289	9	,	,	PUNCT
cusj-7408	289	10	m.	m.	NOUN
cusj-7408	289	11	,	,	PUNCT
cusj-7408	289	12	sakata	sakata	NOUN
cusj-7408	289	13	,	,	PUNCT
cusj-7408	289	14	k.	k.	PROPN
cusj-7408	289	15	,	,	PUNCT
cusj-7408	289	16	okubo	okubo	PROPN
cusj-7408	289	17	,	,	PUNCT
cusj-7408	289	18	y.	y.	PROPN
cusj-7408	289	19	,	,	PUNCT
cusj-7408	289	20	oishi	oishi	PROPN
cusj-7408	289	21	,	,	PUNCT
cusj-7408	289	22	m.	m.	NOUN
cusj-7408	289	23	,	,	PUNCT
cusj-7408	289	24	tanaka	tanaka	PROPN
cusj-7408	289	25	,	,	PUNCT
cusj-7408	289	26	k.	k.	PROPN
cusj-7408	289	27	,	,	PUNCT
cusj-7408	289	28	kobayashi	kobayashi	PROPN
cusj-7408	289	29	,	,	PUNCT
cusj-7408	289	30	e.	e.	PROPN
cusj-7408	289	31	,	,	PUNCT
cusj-7408	289	32	kido	kido	NOUN
cusj-7408	289	33	,	,	PUNCT
cusj-7408	289	34	t.	t.	PROPN
cusj-7408	289	35	,	,	PUNCT
cusj-7408	289	36	and	and	CCONJ
cusj-7408	289	37	nogawa	nogawa	PROPN
cusj-7408	289	38	,	,	PUNCT
cusj-7408	289	39	k.	k.	PROPN
cusj-7408	289	40	(	(	PUNCT
cusj-7408	289	41	2008	2008	NUM
cusj-7408	289	42	)	)	PUNCT
cusj-7408	289	43	.	.	PUNCT
cusj-7408	290	1	a	a	DET
cusj-7408	290	2	longitudinal	longitudinal	ADJ
cusj-7408	290	3	study	study	NOUN
cusj-7408	290	4	on	on	ADP
cusj-7408	290	5	the	the	DET
cusj-7408	290	6	effect	effect	NOUN
cusj-7408	290	7	of	of	ADP
cusj-7408	290	8	shift	shift	NOUN
cusj-7408	290	9	work	work	NOUN
cusj-7408	290	10	on	on	ADP
cusj-7408	290	11	weight	weight	NOUN
cusj-7408	290	12	gain	gain	NOUN
cusj-7408	290	13	in	in	ADP
cusj-7408	290	14	male	male	ADJ
cusj-7408	290	15	japanese	japanese	ADJ
cusj-7408	290	16	workers	worker	NOUN
cusj-7408	290	17	.	.	PUNCT
cusj-7408	291	1	obesity	obesity	NOUN
cusj-7408	291	2	[	[	X
cusj-7408	291	3	25	25	NUM
cusj-7408	291	4	]	]	PUNCT
cusj-7408	291	5	obesity	obesity	NOUN
cusj-7408	291	6	and	and	CCONJ
cusj-7408	291	7	overweight	overweight	NOUN
cusj-7408	291	8	.	.	PUNCT
cusj-7408	292	1	https://www	https://www	PROPN
cusj-7408	292	2	.	.	PUNCT
cusj-7408	293	1	who.int/news-room/fact-sheets/detail/obesity-and-overweight	who.int/news-room/fact-sheets/detail/obesity-and-overweight	PROPN
cusj-7408	293	2	.	.	PUNCT
cusj-7408	294	1	accessed	access	VERB
cusj-7408	294	2	20	20	NUM
cusj-7408	294	3	dec	dec	PROPN
cusj-7408	294	4	.	.	PROPN
cusj-7408	294	5	2020	2020	NUM
cusj-7408	294	6	.	.	PUNCT
cusj-7408	295	1	[	[	X
cusj-7408	295	2	26	26	NUM
cusj-7408	295	3	]	]	PUNCT
cusj-7408	295	4	nojkov	nojkov	ADJ
cusj-7408	295	5	,	,	PUNCT
cusj-7408	295	6	borko	borko	PROPN
cusj-7408	295	7	,	,	PUNCT
cusj-7408	295	8	et	et	PROPN
cusj-7408	295	9	al	al	PROPN
cusj-7408	295	10	.	.	PUNCT
cusj-7408	296	1	“	"	PUNCT
cusj-7408	296	2	the	the	DET
cusj-7408	296	3	impact	impact	NOUN
cusj-7408	296	4	of	of	ADP
cusj-7408	296	5	rotating	rotate	VERB
cusj-7408	296	6	shift	shift	NOUN
cusj-7408	296	7	work	work	NOUN
cusj-7408	296	8	on	on	ADP
cusj-7408	296	9	the	the	DET
cusj-7408	296	10	prevalence	prevalence	NOUN
cusj-7408	296	11	of	of	ADP
cusj-7408	296	12	irritable	irritable	ADJ
cusj-7408	296	13	bowel	bowel	NOUN
cusj-7408	296	14	syndrome	syndrome	NOUN
cusj-7408	296	15	in	in	ADP
cusj-7408	296	16	nurses	nurse	NOUN
cusj-7408	296	17	.	.	PUNCT
cusj-7408	296	18	”	"	PUNCT
cusj-7408	297	1	the	the	DET
cusj-7408	297	2	american	american	PROPN
cusj-7408	297	3	journal	journal	PROPN
cusj-7408	297	4	of	of	ADP
cusj-7408	297	5	gastroenterology	gastroenterology	NOUN
cusj-7408	297	6	,	,	PUNCT
cusj-7408	297	7	vol	vol	NOUN
cusj-7408	297	8	.	.	PROPN
cusj-7408	297	9	105	105	NUM
cusj-7408	297	10	,	,	PUNCT
cusj-7408	297	11	no	no	INTJ
cusj-7408	297	12	.	.	NOUN
cusj-7408	297	13	4	4	NUM
cusj-7408	297	14	,	,	PUNCT
cusj-7408	297	15	apr	apr	PROPN
cusj-7408	297	16	.	.	PROPN
cusj-7408	297	17	2010	2010	NUM
cusj-7408	297	18	,	,	PUNCT
cusj-7408	297	19	pp	pp	ADV
cusj-7408	297	20	.	.	PUNCT
cusj-7408	298	1	842–47	842–47	NUM
cusj-7408	298	2	.	.	PUNCT
cusj-7408	299	1	pubmed	pubmed	PROPN
cusj-7408	299	2	central	central	PROPN
cusj-7408	299	3	,	,	PUNCT
cusj-7408	299	4	doi:10.1038	doi:10.1038	PROPN
cusj-7408	299	5	/	/	SYM
cusj-7408	299	6	ajg.2010.48	ajg.2010.48	PROPN
cusj-7408	299	7	.	.	PUNCT
cusj-7408	300	1	[	[	X
cusj-7408	300	2	27	27	NUM
cusj-7408	300	3	]	]	X
cusj-7408	300	4	thaiss	thaiss	NOUN
cusj-7408	300	5	ca	can	AUX
cusj-7408	300	6	,	,	PUNCT
cusj-7408	300	7	levy	levy	VERB
cusj-7408	300	8	m	m	PRON
cusj-7408	300	9	,	,	PUNCT
cusj-7408	300	10	grosheva	grosheva	PROPN
cusj-7408	300	11	i	i	PRON
cusj-7408	300	12	,	,	PUNCT
cusj-7408	300	13	zheng	zheng	PROPN
cusj-7408	300	14	d	d	PROPN
cusj-7408	300	15	,	,	PUNCT
cusj-7408	300	16	soffer	soffer	NOUN
cusj-7408	300	17	e	e	NOUN
cusj-7408	300	18	,	,	PUNCT
cusj-7408	300	19	blacher	blacher	NOUN
cusj-7408	300	20	e	e	NOUN
cusj-7408	300	21	,	,	PUNCT
cusj-7408	300	22	et	et	PROPN
cusj-7408	300	23	al	al	PROPN
cusj-7408	300	24	.	.	PUNCT
cusj-7408	300	25	hyperglycemia	hyperglycemia	NOUN
cusj-7408	300	26	drives	drive	VERB
cusj-7408	300	27	intestinal	intestinal	ADJ
cusj-7408	300	28	barrier	barrier	NOUN
cusj-7408	300	29	dysfunction	dysfunction	NOUN
cusj-7408	300	30	and	and	CCONJ
cusj-7408	300	31	risk	risk	NOUN
cusj-7408	300	32	for	for	ADP
cusj-7408	300	33	enteric	enteric	ADJ
cusj-7408	300	34	infection	infection	NOUN
cusj-7408	300	35	.	.	PUNCT
cusj-7408	301	1	science	science	NOUN
cusj-7408	301	2	.	.	PUNCT
cusj-7408	302	1	2018;359:1376–1	2018;359:1376–1	NOUN
