id	sid	tid	token	lemma	pos
cbi-68	1	1	44	44	NUM
cbi-68	1	2	letters	letter	NOUN
cbi-68	1	3	and	and	CCONJ
cbi-68	1	4	notes	note	NOUN
cbi-68	1	5	figure	figure	VERB
cbi-68	1	6	2	2	NUM
cbi-68	1	7	:	:	PUNCT
cbi-68	1	8	a	a	DET
cbi-68	1	9	deceitful	deceitful	ADJ
cbi-68	1	10	landscape	landscape	NOUN
cbi-68	1	11	0	0	NUM
cbi-68	2	1	200	200	NUM
cbi-68	2	2	400	400	NUM
cbi-68	2	3	600	600	NUM
cbi-68	2	4	800	800	NUM
cbi-68	2	5	1000	1000	NUM
cbi-68	2	6	0	0	NUM
cbi-68	2	7	2	2	NUM
cbi-68	2	8	0	0	NUM
cbi-68	2	9	4	4	NUM
cbi-68	2	10	0	0	NUM
cbi-68	2	11	6	6	NUM
cbi-68	2	12	0	0	NUM
cbi-68	2	13	8	8	NUM
cbi-68	2	14	0	0	NUM
cbi-68	2	15	1	1	NUM
cbi-68	2	16	0	0	NUM
cbi-68	2	17	0	0	NUM
cbi-68	2	18	iteration	iteration	NOUN
cbi-68	2	19	f	f	NOUN
cbi-68	2	20	itn	itn	NOUN
cbi-68	2	21	e	e	NOUN
cbi-68	2	22	ss	ss	NOUN
cbi-68	2	23	0	0	NUM
cbi-68	2	24	200	200	NUM
cbi-68	2	25	400	400	NUM
cbi-68	2	26	600	600	NUM
cbi-68	2	27	800	800	NUM
cbi-68	2	28	1000	1000	NUM
cbi-68	2	29	0	0	NUM
cbi-68	2	30	2	2	NUM
cbi-68	2	31	0	0	NUM
cbi-68	2	32	4	4	NUM
cbi-68	2	33	0	0	NUM
cbi-68	2	34	6	6	NUM
cbi-68	2	35	0	0	NUM
cbi-68	2	36	8	8	NUM
cbi-68	2	37	0	0	NUM
cbi-68	2	38	1	1	NUM
cbi-68	2	39	0	0	NUM
cbi-68	2	40	0	0	NUM
cbi-68	2	41	iteration	iteration	NOUN
cbi-68	2	42	f	f	NOUN
cbi-68	2	43	itn	itn	NOUN
cbi-68	3	1	e	e	NOUN
cbi-68	3	2	ss	ss	NOUN
cbi-68	3	3	s	s	VERB
cbi-68	3	4	i	i	NOUN
cbi-68	3	5	m	m	VERB
cbi-68	3	6	ila	ila	INTJ
cbi-68	3	7	ri	ri	PROPN
cbi-68	4	1	ty	ty	INTJ
cbi-68	4	2	0	0	NUM
cbi-68	4	3	2	2	NUM
cbi-68	4	4	0	0	NUM
cbi-68	4	5	4	4	NUM
cbi-68	4	6	0	0	NUM
cbi-68	4	7	6	6	NUM
cbi-68	4	8	0	0	NUM
cbi-68	4	9	8	8	NUM
cbi-68	4	10	0	0	NUM
cbi-68	4	11	1	1	NUM
cbi-68	4	12	0	0	NUM
cbi-68	4	13	0	0	NUM
cbi-68	4	14	genome	genome	NOUN
cbi-68	4	15	fitness	fitness	NOUN
cbi-68	4	16	similarity	similarity	NOUN
cbi-68	4	17	to	to	ADP
cbi-68	4	18	optimal	optimal	ADJ
cbi-68	4	19	is	be	AUX
cbi-68	4	20	active	active	ADJ
cbi-68	4	21	information	information	NOUN
cbi-68	4	22	applicable	applicable	ADJ
cbi-68	4	23	to	to	ADP
cbi-68	4	24	biology	biology	NOUN
cbi-68	4	25	?	?	PUNCT
cbi-68	5	1	jonathan	jonathan	PROPN
cbi-68	5	2	bartlett	bartlett	PROPN
cbi-68	5	3	doi	doi	PROPN
cbi-68	5	4	:	:	PUNCT
cbi-68	5	5	10.33014	10.33014	NUM
cbi-68	5	6	/	/	SYM
cbi-68	5	7	issn.2640	issn.2640	ADJ
cbi-68	5	8	-	-	PUNCT
cbi-68	5	9	5652.2.2.bartlett.2	5652.2.2.bartlett.2	NUM
cbi-68	5	10	active	active	ADJ
cbi-68	5	11	information	information	NOUN
cbi-68	5	12	was	be	AUX
cbi-68	5	13	originally	originally	ADV
cbi-68	5	14	introduced	introduce	VERB
cbi-68	5	15	in	in	ADP
cbi-68	5	16	2009	2009	NUM
cbi-68	5	17	by	by	ADP
cbi-68	5	18	william	william	PROPN
cbi-68	5	19	dembski	dembski	PROPN
cbi-68	5	20	and	and	CCONJ
cbi-68	5	21	robert	robert	PROPN
cbi-68	5	22	marks	marks	PROPN
cbi-68	5	23	ii	ii	PROPN
cbi-68	5	24	(	(	PUNCT
cbi-68	5	25	dembski	dembski	NOUN
cbi-68	5	26	and	and	CCONJ
cbi-68	5	27	marks	mark	NOUN
cbi-68	5	28	ii	ii	PROPN
cbi-68	5	29	,	,	PUNCT
cbi-68	5	30	2009	2009	NUM
cbi-68	5	31	)	)	PUNCT
cbi-68	5	32	.	.	PUNCT
cbi-68	6	1	active	active	ADJ
cbi-68	6	2	information	information	NOUN
cbi-68	6	3	identifies	identify	VERB
cbi-68	6	4	how	how	SCONJ
cbi-68	6	5	much	much	ADJ
cbi-68	6	6	information	information	NOUN
cbi-68	6	7	that	that	SCONJ
cbi-68	6	8	a	a	DET
cbi-68	6	9	search	search	NOUN
cbi-68	6	10	has	have	AUX
cbi-68	6	11	compared	compare	VERB
cbi-68	6	12	to	to	ADP
cbi-68	6	13	a	a	DET
cbi-68	6	14	“	"	PUNCT
cbi-68	6	15	random	random	ADJ
cbi-68	6	16	search	search	NOUN
cbi-68	6	17	.	.	PUNCT
cbi-68	6	18	”	"	PUNCT
cbi-68	7	1	introduced	introduce	VERB
cbi-68	7	2	in	in	ADP
cbi-68	7	3	the	the	DET
cbi-68	7	4	context	context	NOUN
cbi-68	7	5	of	of	ADP
cbi-68	7	6	information	information	NOUN
cbi-68	7	7	science	science	NOUN
cbi-68	7	8	,	,	PUNCT
cbi-68	7	9	it	it	PRON
cbi-68	7	10	was	be	AUX
cbi-68	7	11	originally	originally	ADV
cbi-68	7	12	utilized	utilize	VERB
cbi-68	7	13	towards	towards	ADP
cbi-68	7	14	identifying	identify	VERB
cbi-68	7	15	information	information	NOUN
cbi-68	7	16	sources	source	NOUN
cbi-68	7	17	in	in	ADP
cbi-68	7	18	various	various	ADJ
cbi-68	7	19	computerized	computerized	ADJ
cbi-68	7	20	forms	form	NOUN
cbi-68	7	21	and	and	CCONJ
cbi-68	7	22	simulations	simulation	NOUN
cbi-68	7	23	of	of	ADP
cbi-68	7	24	evolution	evolution	NOUN
cbi-68	7	25	.	.	PUNCT
cbi-68	8	1	the	the	DET
cbi-68	8	2	reason	reason	NOUN
cbi-68	8	3	why	why	SCONJ
cbi-68	8	4	active	active	ADJ
cbi-68	8	5	information	information	NOUN
cbi-68	8	6	works	work	VERB
cbi-68	8	7	is	be	AUX
cbi-68	8	8	because	because	SCONJ
cbi-68	8	9	there	there	PRON
cbi-68	8	10	is	be	VERB
cbi-68	8	11	no	no	DET
cbi-68	8	12	general	general	ADJ
cbi-68	8	13	“	"	PUNCT
cbi-68	8	14	best	good	ADJ
cbi-68	8	15	”	"	PUNCT
cbi-68	8	16	algorithm	algorithm	NOUN
cbi-68	8	17	for	for	ADP
cbi-68	8	18	searching	search	VERB
cbi-68	8	19	.	.	PUNCT
cbi-68	9	1	a	a	DET
cbi-68	9	2	search	search	NOUN
cbi-68	9	3	that	that	PRON
cbi-68	9	4	is	be	AUX
cbi-68	9	5	good	good	ADJ
cbi-68	9	6	in	in	ADP
cbi-68	9	7	one	one	NUM
cbi-68	9	8	context	context	NOUN
cbi-68	9	9	will	will	AUX
cbi-68	9	10	be	be	AUX
cbi-68	9	11	terrible	terrible	ADJ
cbi-68	9	12	in	in	ADP
cbi-68	9	13	another	another	PRON
cbi-68	9	14	.	.	PUNCT
cbi-68	10	1	there	there	PRON
cbi-68	10	2	might	might	AUX
cbi-68	10	3	be	be	AUX
cbi-68	10	4	a	a	DET
cbi-68	10	5	best	good	ADJ
cbi-68	10	6	search	search	NOUN
cbi-68	10	7	for	for	ADP
cbi-68	10	8	a	a	DET
cbi-68	10	9	particular	particular	ADJ
cbi-68	10	10	situation	situation	NOUN
cbi-68	10	11	,	,	PUNCT
cbi-68	10	12	but	but	CCONJ
cbi-68	10	13	not	not	PART
cbi-68	10	14	one	one	NOUN
cbi-68	10	15	that	that	PRON
cbi-68	10	16	serves	serve	VERB
cbi-68	10	17	all	all	DET
cbi-68	10	18	situations	situation	NOUN
cbi-68	10	19	equally	equally	ADV
cbi-68	10	20	.	.	PUNCT
cbi-68	11	1	in	in	ADP
cbi-68	11	2	fact	fact	NOUN
cbi-68	11	3	,	,	PUNCT
cbi-68	11	4	it	it	PRON
cbi-68	11	5	turns	turn	VERB
cbi-68	11	6	out	out	ADP
cbi-68	11	7	that	that	SCONJ
cbi-68	11	8	,	,	PUNCT
cbi-68	11	9	for	for	ADP
cbi-68	11	10	any	any	DET
cbi-68	11	11	particular	particular	ADJ
cbi-68	11	12	search	search	NOUN
cbi-68	11	13	situation	situation	NOUN
cbi-68	11	14	,	,	PUNCT
cbi-68	11	15	a	a	DET
cbi-68	11	16	random	random	ADJ
cbi-68	11	17	search	search	NOUN
cbi-68	11	18	has	have	VERB
cbi-68	11	19	average	average	ADJ
cbi-68	11	20	performance	performance	NOUN
cbi-68	11	21	characteristics	characteristic	NOUN
cbi-68	11	22	compared	compare	VERB
cbi-68	11	23	to	to	ADP
cbi-68	11	24	any	any	DET
cbi-68	11	25	other	other	ADJ
cbi-68	11	26	search	search	NOUN
cbi-68	11	27	algorithm	algorithm	NOUN
cbi-68	11	28	.	.	PUNCT
cbi-68	12	1	therefore	therefore	ADV
cbi-68	12	2	,	,	PUNCT
cbi-68	12	3	for	for	ADP
cbi-68	12	4	any	any	DET
cbi-68	12	5	search	search	NOUN
cbi-68	12	6	situation	situation	NOUN
cbi-68	12	7	,	,	PUNCT
cbi-68	12	8	we	we	PRON
cbi-68	12	9	have	have	VERB
cbi-68	12	10	the	the	DET
cbi-68	12	11	capability	capability	NOUN
cbi-68	12	12	of	of	ADP
cbi-68	12	13	determining	determine	VERB
cbi-68	12	14	what	what	PRON
cbi-68	12	15	the	the	DET
cbi-68	12	16	average	average	ADJ
cbi-68	12	17	success	success	NOUN
cbi-68	12	18	rate	rate	NOUN
cbi-68	12	19	for	for	ADP
cbi-68	12	20	a	a	DET
cbi-68	12	21	search	search	NOUN
cbi-68	12	22	should	should	AUX
cbi-68	12	23	be	be	AUX
cbi-68	12	24	(	(	PUNCT
cbi-68	12	25	note	note	VERB
cbi-68	12	26	that	that	SCONJ
cbi-68	12	27	the	the	DET
cbi-68	12	28	success	success	NOUN
cbi-68	12	29	rate	rate	NOUN
cbi-68	12	30	is	be	AUX
cbi-68	12	31	how	how	SCONJ
cbi-68	12	32	many	many	ADJ
cbi-68	12	33	times	time	NOUN
cbi-68	12	34	the	the	DET
cbi-68	12	35	search	search	NOUN
cbi-68	12	36	algorith	algorith	PROPN
cbi-68	12	37	has	have	VERB
cbi-68	12	38	to	to	PART
cbi-68	12	39	“	"	PUNCT
cbi-68	12	40	look	look	VERB
cbi-68	12	41	”	"	PUNCT
cbi-68	12	42	before	before	ADP
cbi-68	12	43	finding	find	VERB
cbi-68	12	44	a	a	DET
cbi-68	12	45	successful	successful	ADJ
cbi-68	12	46	hit	hit	NOUN
cbi-68	12	47	)	)	PUNCT
cbi-68	12	48	.	.	PUNCT
cbi-68	13	1	if	if	SCONJ
cbi-68	13	2	we	we	PRON
cbi-68	13	3	simply	simply	ADV
cbi-68	13	4	perform	perform	VERB
cbi-68	13	5	a	a	DET
cbi-68	13	6	random	random	ADJ
cbi-68	13	7	search	search	NOUN
cbi-68	13	8	and	and	CCONJ
cbi-68	13	9	measure	measure	NOUN
cbi-68	13	10	successes	success	NOUN
cbi-68	13	11	,	,	PUNCT
cbi-68	13	12	we	we	PRON
cbi-68	13	13	can	can	AUX
cbi-68	13	14	determine	determine	VERB
cbi-68	13	15	the	the	DET
cbi-68	13	16	average	average	ADJ
cbi-68	13	17	value	value	NOUN
cbi-68	13	18	.	.	PUNCT
cbi-68	14	1	in	in	ADP
cbi-68	14	2	terms	term	NOUN
cbi-68	14	3	of	of	ADP
cbi-68	14	4	statistics	statistic	NOUN
cbi-68	14	5	,	,	PUNCT
cbi-68	14	6	this	this	DET
cbi-68	14	7	average	average	ADJ
cbi-68	14	8	value	value	NOUN
cbi-68	14	9	is	be	AUX
cbi-68	14	10	the	the	DET
cbi-68	14	11	expected	expect	VERB
cbi-68	14	12	value	value	NOUN
cbi-68	14	13	for	for	ADP
cbi-68	14	14	the	the	DET
cbi-68	14	15	success	success	NOUN
cbi-68	14	16	rate	rate	NOUN
cbi-68	14	17	for	for	ADP
cbi-68	14	18	a	a	DET
cbi-68	14	19	search	search	NOUN
cbi-68	14	20	strategy	strategy	NOUN
cbi-68	14	21	chosen	choose	VERB
cbi-68	14	22	arbitrarily	arbitrarily	ADV
cbi-68	14	23	.	.	PUNCT
cbi-68	15	1	that	that	PRON
cbi-68	15	2	is	be	AUX
cbi-68	15	3	,	,	PUNCT
cbi-68	15	4	if	if	SCONJ
cbi-68	15	5	the	the	DET
cbi-68	15	6	search	search	NOUN
cbi-68	15	7	strategy	strategy	NOUN
cbi-68	15	8	is	be	AUX
cbi-68	15	9	chosen	choose	VERB
cbi-68	15	10	arbitrarily	arbitrarily	ADV
cbi-68	15	11	,	,	PUNCT
cbi-68	15	12	we	we	PRON
cbi-68	15	13	would	would	AUX
cbi-68	15	14	expect	expect	VERB
cbi-68	15	15	that	that	SCONJ
cbi-68	15	16	the	the	DET
cbi-68	15	17	success	success	NOUN
cbi-68	15	18	rate	rate	NOUN
cbi-68	15	19	should	should	AUX
cbi-68	15	20	be	be	AUX
cbi-68	15	21	roughly	roughly	ADV
cbi-68	15	22	equivalent	equivalent	ADJ
cbi-68	15	23	to	to	ADP
cbi-68	15	24	that	that	PRON
cbi-68	15	25	of	of	ADP
cbi-68	15	26	a	a	DET
cbi-68	15	27	random	random	ADJ
cbi-68	15	28	search	search	NOUN
cbi-68	15	29	.	.	PUNCT
cbi-68	16	1	active	active	ADJ
cbi-68	16	2	information	information	NOUN
cbi-68	16	3	measures	measure	VERB
cbi-68	16	4	the	the	DET
cbi-68	16	5	distance	distance	NOUN
cbi-68	16	6	between	between	ADP
cbi-68	16	7	the	the	DET
cbi-68	16	8	success	success	NOUN
cbi-68	16	9	rate	rate	NOUN
cbi-68	16	10	that	that	PRON
cbi-68	16	11	we	we	PRON
cbi-68	16	12	actually	actually	ADV
cbi-68	16	13	observe	observe	VERB
cbi-68	16	14	and	and	CCONJ
cbi-68	16	15	the	the	DET
cbi-68	16	16	success	success	NOUN
cbi-68	16	17	rate	rate	NOUN
cbi-68	16	18	that	that	PRON
cbi-68	16	19	we	we	PRON
cbi-68	16	20	would	would	AUX
cbi-68	16	21	expect	expect	VERB
cbi-68	16	22	from	from	ADP
cbi-68	16	23	an	an	DET
cbi-68	16	24	arbitrarily	arbitrarily	ADV
cbi-68	16	25	chosen	choose	VERB
cbi-68	16	26	search	search	NOUN
cbi-68	16	27	strategy	strategy	NOUN
cbi-68	16	28	.	.	PUNCT
cbi-68	17	1	if	if	SCONJ
cbi-68	17	2	this	this	PRON
cbi-68	17	3	is	be	AUX
cbi-68	17	4	measured	measure	VERB
cbi-68	17	5	prior	prior	ADV
cbi-68	17	6	to	to	ADP
cbi-68	17	7	selection	selection	NOUN
cbi-68	17	8	a!ecting	a!ecte	VERB
cbi-68	17	9	the	the	DET
cbi-68	17	10	success	success	NOUN
cbi-68	17	11	rate	rate	NOUN
cbi-68	17	12	,	,	PUNCT
cbi-68	17	13	we	we	PRON
cbi-68	17	14	can	can	AUX
cbi-68	17	15	then	then	ADV
cbi-68	17	16	measure	measure	VERB
cbi-68	17	17	the	the	DET
cbi-68	17	18	distance	distance	NOUN
cbi-68	17	19	between	between	ADP
cbi-68	17	20	the	the	DET
cbi-68	17	21	success	success	NOUN
cbi-68	17	22	rate	rate	NOUN
cbi-68	17	23	that	that	SCONJ
cbi-68	17	24	the	the	DET
cbi-68	17	25	cell	cell	NOUN
cbi-68	17	26	’s	’s	PART
cbi-68	17	27	own	own	ADJ
cbi-68	17	28	mutational	mutational	ADJ
cbi-68	17	29	machinery	machinery	NOUN
cbi-68	17	30	is	be	AUX
cbi-68	17	31	having	have	VERB
cbi-68	17	32	and	and	CCONJ
cbi-68	17	33	the	the	DET
cbi-68	17	34	success	success	NOUN
cbi-68	17	35	rate	rate	NOUN
cbi-68	17	36	that	that	PRON
cbi-68	17	37	we	we	PRON
cbi-68	17	38	would	would	AUX
cbi-68	17	39	expect	expect	VERB
cbi-68	17	40	from	from	ADP
cbi-68	17	41	arbitrary	arbitrary	ADJ
cbi-68	17	42	mutation	mutation	NOUN
cbi-68	17	43	strategies	strategy	NOUN
cbi-68	17	44	.	.	PUNCT
cbi-68	18	1	this	this	PRON
cbi-68	18	2	will	will	AUX
cbi-68	18	3	tell	tell	VERB
cbi-68	18	4	us	we	PRON
cbi-68	18	5	the	the	DET
cbi-68	18	6	amount	amount	NOUN
cbi-68	18	7	of	of	ADP
cbi-68	18	8	information	information	NOUN
cbi-68	18	9	that	that	SCONJ
cbi-68	18	10	the	the	DET
cbi-68	18	11	cell	cell	NOUN
cbi-68	18	12	’s	’s	PART
cbi-68	18	13	mutational	mutational	ADJ
cbi-68	18	14	machinery	machinery	NOUN
cbi-68	18	15	has	have	VERB
cbi-68	18	16	for	for	ADP
cbi-68	18	17	finding	find	VERB
cbi-68	18	18	a	a	DET
cbi-68	18	19	solution	solution	NOUN
cbi-68	18	20	in	in	ADP
cbi-68	18	21	a	a	DET
cbi-68	18	22	given	give	VERB
cbi-68	18	23	selective	selective	ADJ
cbi-68	18	24	process	process	NOUN
cbi-68	18	25	.	.	PUNCT
cbi-68	19	1	recently	recently	ADV
cbi-68	19	2	,	,	PUNCT
cbi-68	19	3	i	i	PRON
cbi-68	19	4	demonstrated	demonstrate	VERB
cbi-68	19	5	how	how	SCONJ
cbi-68	19	6	this	this	PRON
cbi-68	19	7	could	could	AUX
cbi-68	19	8	be	be	AUX
cbi-68	19	9	measured	measure	VERB
cbi-68	19	10	in	in	ADP
cbi-68	19	11	biological	biological	ADJ
cbi-68	19	12	systems	system	NOUN
cbi-68	19	13	,	,	PUNCT
cbi-68	19	14	giving	give	VERB
cbi-68	19	15	examples	example	NOUN
cbi-68	19	16	for	for	ADP
cbi-68	19	17	how	how	SCONJ
cbi-68	19	18	di!erent	di!erent	NOUN
cbi-68	19	19	types	type	NOUN
cbi-68	19	20	of	of	ADP
cbi-68	19	21	systems	system	NOUN
cbi-68	19	22	might	might	AUX
cbi-68	19	23	be	be	AUX
cbi-68	19	24	measured	measure	VERB
cbi-68	19	25	(	(	PUNCT
cbi-68	19	26	bartlett	bartlett	NOUN
cbi-68	19	27	,	,	PUNCT
cbi-68	19	28	2020	2020	NUM
cbi-68	19	29	)	)	PUNCT
cbi-68	19	30	.	.	PUNCT
cbi-68	20	1	since	since	SCONJ
cbi-68	20	2	this	this	PRON
cbi-68	20	3	is	be	AUX
cbi-68	20	4	a	a	DET
cbi-68	20	5	fairly	fairly	ADV
cbi-68	20	6	new	new	ADJ
cbi-68	20	7	approach	approach	NOUN
cbi-68	20	8	for	for	ADP
cbi-68	20	9	thinking	think	VERB
cbi-68	20	10	about	about	ADP
cbi-68	20	11	mutations	mutation	NOUN
cbi-68	20	12	in	in	ADP
cbi-68	20	13	the	the	DET
cbi-68	20	14	genome	genome	NOUN
cbi-68	20	15	,	,	PUNCT
cbi-68	20	16	there	there	PRON
cbi-68	20	17	are	be	VERB
cbi-68	20	18	many	many	ADJ
cbi-68	20	19	confusions	confusion	NOUN
cbi-68	20	20	about	about	ADP
cbi-68	20	21	what	what	PRON
cbi-68	20	22	is	be	AUX
cbi-68	20	23	actually	actually	ADV
cbi-68	20	24	being	be	AUX
cbi-68	20	25	claimed	claim	VERB
cbi-68	20	26	and	and	CCONJ
cbi-68	20	27	proposed	propose	VERB
cbi-68	20	28	.	.	PUNCT
cbi-68	21	1	this	this	DET
cbi-68	21	2	note	note	NOUN
cbi-68	21	3	intends	intend	VERB
cbi-68	21	4	to	to	PART
cbi-68	21	5	clarify	clarify	VERB
cbi-68	21	6	,	,	PUNCT
cbi-68	21	7	explain	explain	VERB
cbi-68	21	8	,	,	PUNCT
cbi-68	21	9	and	and	CCONJ
cbi-68	21	10	defend	defend	VERB
cbi-68	21	11	the	the	DET
cbi-68	21	12	notions	notion	NOUN
cbi-68	21	13	presented	present	VERB
cbi-68	21	14	in	in	ADP
cbi-68	21	15	the	the	DET
cbi-68	21	16	paper	paper	NOUN
cbi-68	21	17	.	.	PUNCT
cbi-68	22	1	addressing	address	VERB
cbi-68	22	2	misconceptions	misconception	NOUN
cbi-68	22	3	i	i	PRON
cbi-68	22	4	want	want	VERB
cbi-68	22	5	to	to	PART
cbi-68	22	6	start	start	VERB
cbi-68	22	7	by	by	ADP
cbi-68	22	8	clarifying	clarify	VERB
cbi-68	22	9	that	that	SCONJ
cbi-68	22	10	active	active	ADJ
cbi-68	22	11	information	information	NOUN
cbi-68	22	12	does	do	AUX
cbi-68	22	13	not	not	PART
cbi-68	22	14	(	(	PUNCT
cbi-68	22	15	a	a	X
cbi-68	22	16	)	)	PUNCT
cbi-68	22	17	hold	hold	VERB
cbi-68	22	18	that	that	SCONJ
cbi-68	22	19	mutations	mutation	NOUN
cbi-68	22	20	form	form	VERB
cbi-68	22	21	a	a	DET
cbi-68	22	22	uniform	uniform	ADJ
cbi-68	22	23	random	random	ADJ
cbi-68	22	24	distribution	distribution	NOUN
cbi-68	22	25	,	,	PUNCT
cbi-68	22	26	(	(	PUNCT
cbi-68	22	27	b	b	X
cbi-68	22	28	)	)	PUNCT
cbi-68	22	29	hold	hold	VERB
cbi-68	22	30	that	that	SCONJ
cbi-68	22	31	mutations	mutation	NOUN
cbi-68	22	32	should	should	AUX
cbi-68	22	33	form	form	VERB
cbi-68	22	34	a	a	DET
cbi-68	22	35	uniform	uniform	ADJ
cbi-68	22	36	random	random	ADJ
cbi-68	22	37	distribution	distribution	NOUN
cbi-68	22	38	,	,	PUNCT
cbi-68	22	39	or	or	CCONJ
cbi-68	22	40	(	(	PUNCT
cbi-68	22	41	c	c	X
cbi-68	22	42	)	)	PUNCT
cbi-68	22	43	hold	hold	VERB
cbi-68	22	44	that	that	SCONJ
cbi-68	22	45	standard	standard	ADJ
cbi-68	22	46	evolutionary	evolutionary	ADJ
cbi-68	22	47	theory	theory	NOUN
cbi-68	22	48	holds	hold	VERB
cbi-68	22	49	that	that	SCONJ
cbi-68	22	50	mutations	mutation	NOUN
cbi-68	22	51	should	should	AUX
cbi-68	22	52	form	form	VERB
cbi-68	22	53	a	a	DET
cbi-68	22	54	uniform	uniform	ADJ
cbi-68	22	55	random	random	ADJ
cbi-68	22	56	distribution	distribution	NOUN
cbi-68	22	57	.	.	PUNCT
cbi-68	23	1	instead	instead	ADV
cbi-68	23	2	,	,	PUNCT
cbi-68	23	3	active	active	ADJ
cbi-68	23	4	information	information	NOUN
cbi-68	23	5	attempts	attempt	VERB
cbi-68	23	6	to	to	PART
cbi-68	23	7	simulate	simulate	VERB
cbi-68	23	8	a	a	DET
cbi-68	23	9	uniform	uniform	ADJ
cbi-68	23	10	random	random	ADJ
cbi-68	23	11	distribution	distribution	NOUN
cbi-68	23	12	of	of	ADP
cbi-68	23	13	mutations	mutation	NOUN
cbi-68	23	14	in	in	ADP
cbi-68	23	15	order	order	NOUN
cbi-68	23	16	to	to	PART
cbi-68	23	17	get	get	VERB
cbi-68	23	18	an	an	DET
cbi-68	23	19	expected	expect	VERB
cbi-68	23	20	value	value	NOUN
cbi-68	23	21	for	for	ADP
cbi-68	23	22	the	the	DET
cbi-68	23	23	success	success	NOUN
cbi-68	23	24	rate	rate	NOUN
cbi-68	23	25	of	of	ADP
cbi-68	23	26	other	other	ADJ
cbi-68	23	27	mutational	mutational	ADJ
cbi-68	23	28	strategies	strategy	NOUN
cbi-68	23	29	.	.	PUNCT
cbi-68	24	1	this	this	PRON
cbi-68	24	2	follows	follow	VERB
cbi-68	24	3	not	not	PART
cbi-68	24	4	from	from	ADP
cbi-68	24	5	evolutionary	evolutionary	ADJ
cbi-68	24	6	theory	theory	NOUN
cbi-68	24	7	but	but	CCONJ
cbi-68	24	8	rather	rather	ADV
cbi-68	24	9	from	from	ADP
cbi-68	24	10	information	information	NOUN
cbi-68	24	11	theory	theory	NOUN
cbi-68	24	12	,	,	PUNCT
cbi-68	24	13	which	which	PRON
cbi-68	24	14	states	state	VERB
cbi-68	24	15	that	that	SCONJ
cbi-68	24	16	such	such	DET
cbi-68	24	17	a	a	DET
cbi-68	24	18	search	search	NOUN
cbi-68	24	19	will	will	AUX
cbi-68	24	20	give	give	VERB
cbi-68	24	21	you	you	PRON
cbi-68	24	22	the	the	DET
cbi-68	24	23	expected	expect	VERB
cbi-68	24	24	value	value	NOUN
cbi-68	24	25	for	for	ADP
cbi-68	24	26	the	the	DET
cbi-68	24	27	success	success	NOUN
cbi-68	24	28	rate	rate	NOUN
cbi-68	24	29	of	of	ADP
cbi-68	24	30	other	other	ADJ
cbi-68	24	31	searches	search	NOUN
cbi-68	24	32	.	.	PUNCT
cbi-68	25	1	this	this	DET
cbi-68	25	2	distinction	distinction	NOUN
cbi-68	25	3	is	be	AUX
cbi-68	25	4	critical	critical	ADJ
cbi-68	25	5	and	and	CCONJ
cbi-68	25	6	forms	form	VERB
cbi-68	25	7	the	the	DET
cbi-68	25	8	basis	basis	NOUN
cbi-68	25	9	of	of	ADP
cbi-68	25	10	the	the	DET
cbi-68	25	11	logic	logic	NOUN
cbi-68	25	12	of	of	ADP
cbi-68	25	13	applying	apply	VERB
cbi-68	25	14	active	active	ADJ
cbi-68	25	15	information	information	NOUN
cbi-68	25	16	to	to	ADP
cbi-68	25	17	biology	biology	NOUN
cbi-68	25	18	.	.	PUNCT
cbi-68	26	1	another	another	DET
cbi-68	26	2	important	important	ADJ
cbi-68	26	3	clarification	clarification	NOUN
cbi-68	26	4	is	be	AUX
cbi-68	26	5	that	that	SCONJ
cbi-68	26	6	,	,	PUNCT
cbi-68	26	7	as	as	SCONJ
cbi-68	26	8	stated	state	VERB
cbi-68	26	9	in	in	ADP
cbi-68	26	10	the	the	DET
cbi-68	26	11	paper	paper	NOUN
cbi-68	26	12	,	,	PUNCT
cbi-68	26	13	it	it	PRON
cbi-68	26	14	does	do	AUX
cbi-68	26	15	not	not	PART
cbi-68	26	16	matter	matter	VERB
cbi-68	26	17	if	if	SCONJ
cbi-68	26	18	evolution	evolution	NOUN
cbi-68	26	19	is	be	AUX
cbi-68	26	20	ontologically	ontologically	ADV
cbi-68	26	21	a	a	DET
cbi-68	26	22	search	search	NOUN
cbi-68	26	23	.	.	PUNCT
cbi-68	27	1	https://dx.doi.org/10.33014/issn.2640-5652.2.2.bartlett.2	https://dx.doi.org/10.33014/issn.2640-5652.2.2.bartlett.2	NOUN
cbi-68	27	2	volume	volume	NOUN
cbi-68	27	3	2	2	NUM
cbi-68	27	4	,	,	PUNCT
cbi-68	27	5	issue	issue	NOUN
cbi-68	27	6	2	2	NUM
cbi-68	27	7	is	be	AUX
cbi-68	27	8	active	active	ADJ
cbi-68	27	9	information	information	NOUN
cbi-68	27	10	applicable	applicable	ADJ
cbi-68	27	11	to	to	ADP
cbi-68	27	12	biology	biology	NOUN
cbi-68	27	13	?	?	PUNCT
cbi-68	28	1	45	45	NUM
cbi-68	28	2	many	many	ADJ
cbi-68	28	3	incorrectly	incorrectly	ADV
cbi-68	28	4	reject	reject	VERB
cbi-68	28	5	the	the	DET
cbi-68	28	6	application	application	NOUN
cbi-68	28	7	of	of	ADP
cbi-68	28	8	the	the	DET
cbi-68	28	9	mathematics	mathematic	NOUN
cbi-68	28	10	of	of	ADP
cbi-68	28	11	search	search	NOUN
cbi-68	28	12	to	to	ADP
cbi-68	28	13	evolution	evolution	NOUN
cbi-68	28	14	on	on	ADP
cbi-68	28	15	the	the	DET
cbi-68	28	16	basis	basis	NOUN
cbi-68	28	17	that	that	SCONJ
cbi-68	28	18	evolution	evolution	NOUN
cbi-68	28	19	is	be	AUX
cbi-68	28	20	n’t	not	PART
cbi-68	28	21	truly	truly	ADV
cbi-68	28	22	a	a	DET
cbi-68	28	23	search	search	NOUN
cbi-68	28	24	for	for	ADP
cbi-68	28	25	anything	anything	PRON
cbi-68	28	26	.	.	PUNCT
cbi-68	29	1	whether	whether	SCONJ
cbi-68	29	2	or	or	CCONJ
cbi-68	29	3	not	not	PART
cbi-68	29	4	that	that	PRON
cbi-68	29	5	is	be	AUX
cbi-68	29	6	true	true	ADJ
cbi-68	29	7	is	be	AUX
cbi-68	29	8	irrelevant	irrelevant	ADJ
cbi-68	29	9	.	.	PUNCT
cbi-68	30	1	evolution	evolution	NOUN
cbi-68	30	2	(	(	PUNCT
cbi-68	30	3	or	or	CCONJ
cbi-68	30	4	at	at	ADP
cbi-68	30	5	least	least	ADJ
cbi-68	30	6	certain	certain	ADJ
cbi-68	30	7	situations	situation	NOUN
cbi-68	30	8	in	in	ADP
cbi-68	30	9	evolution	evolution	NOUN
cbi-68	30	10	)	)	PUNCT
cbi-68	30	11	matches	match	VERB
cbi-68	30	12	the	the	DET
cbi-68	30	13	mathematical	mathematical	ADJ
cbi-68	30	14	preconditions	precondition	NOUN
cbi-68	30	15	of	of	ADP
cbi-68	30	16	a	a	DET
cbi-68	30	17	search	search	NOUN
cbi-68	30	18	,	,	PUNCT
cbi-68	30	19	and	and	CCONJ
cbi-68	30	20	,	,	PUNCT
cbi-68	30	21	therefore	therefore	ADV
cbi-68	30	22	,	,	PUNCT
cbi-68	30	23	search	search	NOUN
cbi-68	30	24	mathematics	mathematic	NOUN
cbi-68	30	25	applies	apply	VERB
cbi-68	30	26	whether	whether	SCONJ
cbi-68	30	27	or	or	CCONJ
cbi-68	30	28	not	not	PART
cbi-68	30	29	it	it	PRON
cbi-68	30	30	is	be	AUX
cbi-68	30	31	a	a	DET
cbi-68	30	32	search	search	NOUN
cbi-68	30	33	ontologically	ontologically	ADV
cbi-68	30	34	.	.	PUNCT
cbi-68	31	1	if	if	SCONJ
cbi-68	31	2	an	an	DET
cbi-68	31	3	organism	organism	NOUN
cbi-68	31	4	is	be	AUX
cbi-68	31	5	undergoing	undergo	VERB
cbi-68	31	6	selective	selective	ADJ
cbi-68	31	7	pressure	pressure	NOUN
cbi-68	31	8	,	,	PUNCT
cbi-68	31	9	we	we	PRON
cbi-68	31	10	can	can	AUX
cbi-68	31	11	define	define	VERB
cbi-68	31	12	a	a	DET
cbi-68	31	13	“	"	PUNCT
cbi-68	31	14	successful	successful	ADJ
cbi-68	31	15	search	search	NOUN
cbi-68	31	16	”	"	PUNCT
cbi-68	31	17	as	as	ADP
cbi-68	31	18	an	an	DET
cbi-68	31	19	organismal	organismal	ADJ
cbi-68	31	20	configuration	configuration	NOUN
cbi-68	31	21	that	that	PRON
cbi-68	31	22	relieves	relieve	VERB
cbi-68	31	23	that	that	DET
cbi-68	31	24	selective	selective	ADJ
cbi-68	31	25	pressure	pressure	NOUN
cbi-68	31	26	beyond	beyond	ADP
cbi-68	31	27	a	a	DET
cbi-68	31	28	certain	certain	ADJ
cbi-68	31	29	threshold	threshold	NOUN
cbi-68	31	30	.	.	PUNCT
cbi-68	32	1	this	this	PRON
cbi-68	32	2	is	be	AUX
cbi-68	32	3	easiest	easy	ADJ
cbi-68	32	4	to	to	PART
cbi-68	32	5	understand	understand	VERB
cbi-68	32	6	and	and	CCONJ
cbi-68	32	7	measure	measure	VERB
cbi-68	32	8	when	when	SCONJ
cbi-68	32	9	the	the	DET
cbi-68	32	10	selection	selection	NOUN
cbi-68	32	11	is	be	AUX
cbi-68	32	12	lethal	lethal	ADJ
cbi-68	32	13	.	.	PUNCT
cbi-68	33	1	the	the	DET
cbi-68	33	2	search	search	NOUN
cbi-68	33	3	space	space	NOUN
cbi-68	33	4	(	(	PUNCT
cbi-68	33	5	the	the	DET
cbi-68	33	6	genome	genome	NOUN
cbi-68	33	7	)	)	PUNCT
cbi-68	33	8	,	,	PUNCT
cbi-68	33	9	the	the	DET
cbi-68	33	10	search	search	NOUN
cbi-68	33	11	activity	activity	NOUN
cbi-68	33	12	(	(	PUNCT
cbi-68	33	13	mutation	mutation	NOUN
cbi-68	33	14	)	)	PUNCT
cbi-68	33	15	,	,	PUNCT
cbi-68	33	16	and	and	CCONJ
cbi-68	33	17	the	the	DET
cbi-68	33	18	search	search	NOUN
cbi-68	33	19	target	target	NOUN
cbi-68	33	20	(	(	PUNCT
cbi-68	33	21	any	any	DET
cbi-68	33	22	genome	genome	NOUN
cbi-68	33	23	configuration	configuration	NOUN
cbi-68	33	24	that	that	PRON
cbi-68	33	25	relieves	relieve	VERB
cbi-68	33	26	the	the	DET
cbi-68	33	27	selection	selection	NOUN
cbi-68	33	28	pressure	pressure	NOUN
cbi-68	33	29	)	)	PUNCT
cbi-68	33	30	are	be	AUX
cbi-68	33	31	clearly	clearly	ADV
cbi-68	33	32	defined	define	VERB
cbi-68	33	33	.	.	PUNCT
cbi-68	34	1	also	also	ADV
cbi-68	34	2	note	note	VERB
cbi-68	34	3	that	that	SCONJ
cbi-68	34	4	some	some	DET
cbi-68	34	5	people	people	NOUN
cbi-68	34	6	incorrectly	incorrectly	ADV
cbi-68	34	7	believe	believe	VERB
cbi-68	34	8	that	that	SCONJ
cbi-68	34	9	the	the	DET
cbi-68	34	10	mathematics	mathematic	NOUN
cbi-68	34	11	of	of	ADP
cbi-68	34	12	search	search	NOUN
cbi-68	34	13	imply	imply	VERB
cbi-68	34	14	that	that	SCONJ
cbi-68	34	15	we	we	PRON
cbi-68	34	16	are	be	AUX
cbi-68	34	17	looking	look	VERB
cbi-68	34	18	for	for	ADP
cbi-68	34	19	a	a	DET
cbi-68	34	20	specific	specific	ADJ
cbi-68	34	21	target	target	NOUN
cbi-68	34	22	(	(	PUNCT
cbi-68	34	23	i.e.	i.e.	X
cbi-68	34	24	,	,	PUNCT
cbi-68	34	25	dna	dna	NOUN
cbi-68	34	26	sequence	sequence	NOUN
cbi-68	34	27	)	)	PUNCT
cbi-68	34	28	,	,	PUNCT
cbi-68	34	29	or	or	CCONJ
cbi-68	34	30	that	that	SCONJ
cbi-68	34	31	we	we	PRON
cbi-68	34	32	know	know	VERB
cbi-68	34	33	what	what	PRON
cbi-68	34	34	the	the	DET
cbi-68	34	35	target(s	target(s	PROPN
cbi-68	34	36	)	)	PUNCT
cbi-68	34	37	(	(	PUNCT
cbi-68	34	38	dna	dna	PROPN
cbi-68	34	39	sequences	sequence	NOUN
cbi-68	34	40	)	)	PUNCT
cbi-68	34	41	are	be	AUX
cbi-68	34	42	ahead	ahead	ADV
cbi-68	34	43	-	-	PUNCT
cbi-68	34	44	of	of	ADP
cbi-68	34	45	-	-	PUNCT
cbi-68	34	46	time	time	NOUN
cbi-68	34	47	.	.	PUNCT
cbi-68	35	1	this	this	PRON
cbi-68	35	2	is	be	AUX
cbi-68	35	3	not	not	PART
cbi-68	35	4	the	the	DET
cbi-68	35	5	case	case	NOUN
cbi-68	35	6	either	either	ADV
cbi-68	35	7	.	.	PUNCT
cbi-68	36	1	we	we	PRON
cbi-68	36	2	merely	merely	ADV
cbi-68	36	3	have	have	VERB
cbi-68	36	4	to	to	PART
cbi-68	36	5	have	have	VERB
cbi-68	36	6	a	a	DET
cbi-68	36	7	well	well	ADV
cbi-68	36	8	-	-	PUNCT
cbi-68	36	9	defined	define	VERB
cbi-68	36	10	definition	definition	NOUN
cbi-68	36	11	of	of	ADP
cbi-68	36	12	the	the	DET
cbi-68	36	13	target	target	NOUN
cbi-68	36	14	.	.	PUNCT
cbi-68	37	1	in	in	ADP
cbi-68	37	2	this	this	DET
cbi-68	37	3	case	case	NOUN
cbi-68	37	4	,	,	PUNCT
cbi-68	37	5	it	it	PRON
cbi-68	37	6	is	be	AUX
cbi-68	37	7	a	a	DET
cbi-68	37	8	genome	genome	NOUN
cbi-68	37	9	configuration	configuration	NOUN
cbi-68	37	10	that	that	PRON
cbi-68	37	11	relieves	relieve	VERB
cbi-68	37	12	the	the	DET
cbi-68	37	13	selective	selective	ADJ
cbi-68	37	14	pressure	pressure	NOUN
cbi-68	37	15	.	.	PUNCT
cbi-68	38	1	we	we	PRON
cbi-68	38	2	identify	identify	VERB
cbi-68	38	3	it	it	PRON
cbi-68	38	4	not	not	PART
cbi-68	38	5	by	by	ADP
cbi-68	38	6	sequence	sequence	NOUN
cbi-68	38	7	(	(	PUNCT
cbi-68	38	8	since	since	SCONJ
cbi-68	38	9	we	we	PRON
cbi-68	38	10	do	do	AUX
cbi-68	38	11	n’t	not	PART
cbi-68	38	12	know	know	VERB
cbi-68	38	13	what	what	PRON
cbi-68	38	14	sequence(s	sequence(s	PROPN
cbi-68	38	15	)	)	PUNCT
cbi-68	38	16	that	that	PRON
cbi-68	38	17	will	will	AUX
cbi-68	38	18	be	be	AUX
cbi-68	38	19	)	)	PUNCT
cbi-68	38	20	but	but	CCONJ
cbi-68	38	21	by	by	ADP
cbi-68	38	22	result	result	NOUN
cbi-68	38	23	(	(	PUNCT
cbi-68	38	24	relieving	relieve	VERB
cbi-68	38	25	the	the	DET
cbi-68	38	26	selective	selective	ADJ
cbi-68	38	27	pressure	pressure	NOUN
cbi-68	38	28	)	)	PUNCT
cbi-68	38	29	.	.	PUNCT
cbi-68	39	1	methodological	methodological	ADJ
cbi-68	39	2	concerns	concern	NOUN
cbi-68	39	3	one	one	NUM
cbi-68	39	4	potential	potential	ADJ
cbi-68	39	5	concern	concern	NOUN
cbi-68	39	6	is	be	AUX
cbi-68	39	7	that	that	SCONJ
cbi-68	39	8	we	we	PRON
cbi-68	39	9	are	be	AUX
cbi-68	39	10	excluding	exclude	VERB
cbi-68	39	11	the	the	DET
cbi-68	39	12	e!ects	e!ect	NOUN
cbi-68	39	13	of	of	ADP
cbi-68	39	14	the	the	DET
cbi-68	39	15	active	active	ADJ
cbi-68	39	16	information	information	NOUN
cbi-68	39	17	supplied	supply	VERB
cbi-68	39	18	by	by	ADP
cbi-68	39	19	natural	natural	ADJ
cbi-68	39	20	selection	selection	NOUN
cbi-68	39	21	.	.	PUNCT
cbi-68	40	1	the	the	DET
cbi-68	40	2	general	general	ADJ
cbi-68	40	3	method	method	NOUN
cbi-68	40	4	presented	present	VERB
cbi-68	40	5	does	do	AUX
cbi-68	40	6	not	not	PART
cbi-68	40	7	fall	fall	VERB
cbi-68	40	8	prey	prey	NOUN
cbi-68	40	9	to	to	ADP
cbi-68	40	10	that	that	DET
cbi-68	40	11	criticism	criticism	NOUN
cbi-68	40	12	,	,	PUNCT
cbi-68	40	13	as	as	SCONJ
cbi-68	40	14	it	it	PRON
cbi-68	40	15	focuses	focus	VERB
cbi-68	40	16	on	on	ADP
cbi-68	40	17	single	single	ADJ
cbi-68	40	18	-	-	PUNCT
cbi-68	40	19	generation	generation	NOUN
cbi-68	40	20	results	result	NOUN
cbi-68	40	21	(	(	PUNCT
cbi-68	40	22	thus	thus	ADV
cbi-68	40	23	not	not	PART
cbi-68	40	24	allowing	allow	VERB
cbi-68	40	25	for	for	ADP
cbi-68	40	26	natural	natural	ADJ
cbi-68	40	27	selection	selection	NOUN
cbi-68	40	28	to	to	PART
cbi-68	40	29	work	work	NOUN
cbi-68	40	30	)	)	PUNCT
cbi-68	40	31	.	.	PUNCT
cbi-68	41	1	however	however	ADV
cbi-68	41	2	,	,	PUNCT
cbi-68	41	3	it	it	PRON
cbi-68	41	4	is	be	AUX
cbi-68	41	5	true	true	ADJ
cbi-68	41	6	that	that	SCONJ
cbi-68	41	7	,	,	PUNCT
cbi-68	41	8	if	if	SCONJ
cbi-68	41	9	trying	try	VERB
cbi-68	41	10	to	to	PART
cbi-68	41	11	apply	apply	VERB
cbi-68	41	12	active	active	ADJ
cbi-68	41	13	information	information	NOUN
cbi-68	41	14	to	to	ADP
cbi-68	41	15	biology	biology	NOUN
cbi-68	41	16	in	in	ADP
cbi-68	41	17	some	some	DET
cbi-68	41	18	other	other	ADJ
cbi-68	41	19	way	way	NOUN
cbi-68	41	20	,	,	PUNCT
cbi-68	41	21	this	this	PRON
cbi-68	41	22	could	could	AUX
cbi-68	41	23	be	be	AUX
cbi-68	41	24	an	an	DET
cbi-68	41	25	issue	issue	NOUN
cbi-68	41	26	.	.	PUNCT
cbi-68	42	1	pachón	pachón	PROPN
cbi-68	42	2	and	and	CCONJ
cbi-68	42	3	marks	marks	PROPN
cbi-68	42	4	ii	ii	PROPN
cbi-68	42	5	(	(	PUNCT
cbi-68	42	6	2020	2020	NUM
cbi-68	42	7	)	)	PUNCT
cbi-68	42	8	presents	present	VERB
cbi-68	42	9	a	a	DET
cbi-68	42	10	way	way	NOUN
cbi-68	42	11	of	of	ADP
cbi-68	42	12	calculating	calculate	VERB
cbi-68	42	13	the	the	DET
cbi-68	42	14	active	active	ADJ
cbi-68	42	15	information	information	NOUN
cbi-68	42	16	of	of	ADP
cbi-68	42	17	selection	selection	NOUN
cbi-68	42	18	,	,	PUNCT
cbi-68	42	19	which	which	PRON
cbi-68	42	20	may	may	AUX
cbi-68	42	21	point	point	VERB
cbi-68	42	22	towards	towards	ADP
cbi-68	42	23	a	a	DET
cbi-68	42	24	way	way	NOUN
cbi-68	42	25	of	of	ADP
cbi-68	42	26	measuring	measure	VERB
cbi-68	42	27	the	the	DET
cbi-68	42	28	active	active	ADJ
cbi-68	42	29	information	information	NOUN
cbi-68	42	30	in	in	ADP
cbi-68	42	31	the	the	DET
cbi-68	42	32	biological	biological	ADJ
cbi-68	42	33	system	system	NOUN
cbi-68	42	34	in	in	ADP
cbi-68	42	35	experiments	experiment	NOUN
cbi-68	42	36	where	where	SCONJ
cbi-68	42	37	selection	selection	NOUN
cbi-68	42	38	also	also	ADV
cbi-68	42	39	supplies	supply	VERB
cbi-68	42	40	active	active	ADJ
cbi-68	42	41	information	information	NOUN
cbi-68	42	42	as	as	ADV
cbi-68	42	43	well	well	ADV
cbi-68	42	44	.	.	PUNCT
cbi-68	43	1	the	the	DET
cbi-68	43	2	active	active	ADJ
cbi-68	43	3	information	information	NOUN
cbi-68	43	4	supplied	supply	VERB
cbi-68	43	5	by	by	ADP
cbi-68	43	6	selection	selection	NOUN
cbi-68	43	7	may	may	AUX
cbi-68	43	8	actually	actually	ADV
cbi-68	43	9	be	be	AUX
cbi-68	43	10	a	a	DET
cbi-68	43	11	contributing	contribute	VERB
cbi-68	43	12	factor	factor	NOUN
cbi-68	43	13	to	to	ADP
cbi-68	43	14	the	the	DET
cbi-68	43	15	success	success	NOUN
cbi-68	43	16	of	of	ADP
cbi-68	43	17	e.	e.	PROPN
cbi-68	43	18	coli	coli	PROPN
cbi-68	43	19	developing	develop	VERB
cbi-68	43	20	the	the	DET
cbi-68	43	21	cit+	cit+	PROPN
cbi-68	43	22	mutation	mutation	NOUN
cbi-68	43	23	described	describe	VERB
cbi-68	43	24	in	in	ADP
cbi-68	43	25	“	"	PUNCT
cbi-68	43	26	relative	relative	ADJ
cbi-68	43	27	active	active	ADJ
cbi-68	43	28	information	information	NOUN
cbi-68	43	29	”	"	PUNCT
cbi-68	43	30	section	section	NOUN
cbi-68	43	31	of	of	ADP
cbi-68	43	32	bartlett	bartlett	PROPN
cbi-68	43	33	(	(	PUNCT
cbi-68	43	34	2020	2020	NUM
cbi-68	43	35	)	)	PUNCT
cbi-68	43	36	.	.	PUNCT
cbi-68	44	1	further	further	ADJ
cbi-68	44	2	research	research	NOUN
cbi-68	44	3	will	will	AUX
cbi-68	44	4	be	be	AUX
cbi-68	44	5	required	require	VERB
cbi-68	44	6	to	to	PART
cbi-68	44	7	determine	determine	VERB
cbi-68	44	8	how	how	SCONJ
cbi-68	44	9	much	much	ADJ
cbi-68	44	10	of	of	ADP
cbi-68	44	11	an	an	DET
cbi-68	44	12	impact	impact	NOUN
cbi-68	44	13	this	this	PRON
cbi-68	44	14	has	have	VERB
cbi-68	44	15	on	on	ADP
cbi-68	44	16	the	the	DET
cbi-68	44	17	calculation	calculation	NOUN
cbi-68	44	18	.	.	PUNCT
cbi-68	45	1	another	another	DET
cbi-68	45	2	potential	potential	ADJ
cbi-68	45	3	issue	issue	NOUN
cbi-68	45	4	with	with	ADP
cbi-68	45	5	the	the	DET
cbi-68	45	6	measurement	measurement	NOUN
cbi-68	45	7	technique	technique	NOUN
cbi-68	45	8	presented	present	VERB
cbi-68	45	9	in	in	ADP
cbi-68	45	10	bartlett	bartlett	PROPN
cbi-68	45	11	(	(	PUNCT
cbi-68	45	12	2020	2020	NUM
cbi-68	45	13	)	)	PUNCT
cbi-68	45	14	is	be	AUX
cbi-68	45	15	that	that	SCONJ
cbi-68	45	16	,	,	PUNCT
cbi-68	45	17	to	to	PART
cbi-68	45	18	replicate	replicate	VERB
cbi-68	45	19	to	to	ADP
cbi-68	45	20	a	a	DET
cbi-68	45	21	population	population	NOUN
cbi-68	45	22	size	size	NOUN
cbi-68	45	23	adequate	adequate	ADJ
cbi-68	45	24	to	to	PART
cbi-68	45	25	perform	perform	VERB
cbi-68	45	26	the	the	DET
cbi-68	45	27	study	study	NOUN
cbi-68	45	28	,	,	PUNCT
cbi-68	45	29	variation	variation	NOUN
cbi-68	45	30	in	in	ADP
cbi-68	45	31	the	the	DET
cbi-68	45	32	genome	genome	NOUN
cbi-68	45	33	will	will	AUX
cbi-68	45	34	already	already	ADV
cbi-68	45	35	be	be	AUX
cbi-68	45	36	introduced	introduce	VERB
cbi-68	45	37	prior	prior	ADV
cbi-68	45	38	to	to	ADP
cbi-68	45	39	the	the	DET
cbi-68	45	40	study	study	NOUN
cbi-68	45	41	in	in	ADP
cbi-68	45	42	question	question	NOUN
cbi-68	45	43	.	.	PUNCT
cbi-68	46	1	this	this	PRON
cbi-68	46	2	might	might	AUX
cbi-68	46	3	already	already	ADV
cbi-68	46	4	introduce	introduce	VERB
cbi-68	46	5	variety	variety	NOUN
cbi-68	46	6	in	in	ADP
cbi-68	46	7	the	the	DET
cbi-68	46	8	population	population	NOUN
cbi-68	46	9	that	that	PRON
cbi-68	46	10	needs	need	VERB
cbi-68	46	11	to	to	PART
cbi-68	46	12	be	be	AUX
cbi-68	46	13	accounted	account	VERB
cbi-68	46	14	for	for	ADP
cbi-68	46	15	either	either	CCONJ
cbi-68	46	16	experimentally	experimentally	ADV
cbi-68	46	17	or	or	CCONJ
cbi-68	46	18	mathematically	mathematically	ADV
cbi-68	46	19	.	.	PUNCT
cbi-68	47	1	a	a	DET
cbi-68	47	2	simple	simple	ADJ
cbi-68	47	3	way	way	NOUN
cbi-68	47	4	to	to	PART
cbi-68	47	5	adapt	adapt	VERB
cbi-68	47	6	for	for	ADP
cbi-68	47	7	this	this	PRON
cbi-68	47	8	is	be	AUX
cbi-68	47	9	to	to	PART
cbi-68	47	10	begin	begin	VERB
cbi-68	47	11	with	with	ADP
cbi-68	47	12	a	a	DET
cbi-68	47	13	replica	replica	NOUN
cbi-68	47	14	plating	plating	NOUN
cbi-68	47	15	technique	technique	NOUN
cbi-68	47	16	to	to	PART
cbi-68	47	17	filter	filter	VERB
cbi-68	47	18	out	out	ADP
cbi-68	47	19	colonies	colony	NOUN
cbi-68	47	20	that	that	PRON
cbi-68	47	21	already	already	ADV
cbi-68	47	22	have	have	VERB
cbi-68	47	23	a	a	DET
cbi-68	47	24	successful	successful	ADJ
cbi-68	47	25	hit	hit	NOUN
cbi-68	47	26	.	.	PUNCT
cbi-68	48	1	how	how	SCONJ
cbi-68	48	2	targeted	target	VERB
cbi-68	48	3	is	be	AUX
cbi-68	48	4	somatic	somatic	ADJ
cbi-68	48	5	hypermutation	hypermutation	NOUN
cbi-68	48	6	?	?	PUNCT
cbi-68	49	1	bartlett	bartlett	PROPN
cbi-68	49	2	(	(	PUNCT
cbi-68	49	3	2020	2020	NUM
cbi-68	49	4	)	)	PUNCT
cbi-68	49	5	also	also	ADV
cbi-68	49	6	shows	show	VERB
cbi-68	49	7	how	how	SCONJ
cbi-68	49	8	,	,	PUNCT
cbi-68	49	9	using	use	VERB
cbi-68	49	10	certain	certain	ADJ
cbi-68	49	11	assumptions	assumption	NOUN
cbi-68	49	12	,	,	PUNCT
cbi-68	49	13	the	the	DET
cbi-68	49	14	active	active	ADJ
cbi-68	49	15	information	information	NOUN
cbi-68	49	16	calculation	calculation	NOUN
cbi-68	49	17	can	can	AUX
cbi-68	49	18	be	be	AUX
cbi-68	49	19	simplified	simplify	VERB
cbi-68	49	20	.	.	PUNCT
cbi-68	50	1	one	one	NUM
cbi-68	50	2	particular	particular	ADJ
cbi-68	50	3	simplification	simplification	NOUN
cbi-68	50	4	was	be	AUX
cbi-68	50	5	given	give	VERB
cbi-68	50	6	for	for	ADP
cbi-68	50	7	the	the	DET
cbi-68	50	8	somatic	somatic	ADJ
cbi-68	50	9	hypermutation	hypermutation	NOUN
cbi-68	50	10	process	process	NOUN
cbi-68	50	11	.	.	PUNCT
cbi-68	51	1	essentially	essentially	ADV
cbi-68	51	2	,	,	PUNCT
cbi-68	51	3	if	if	SCONJ
cbi-68	51	4	it	it	PRON
cbi-68	51	5	can	can	AUX
cbi-68	51	6	be	be	AUX
cbi-68	51	7	shown	show	VERB
cbi-68	51	8	that	that	SCONJ
cbi-68	51	9	a	a	DET
cbi-68	51	10	particular	particular	ADJ
cbi-68	51	11	mutational	mutational	ADJ
cbi-68	51	12	system	system	NOUN
cbi-68	51	13	occurs	occur	VERB
cbi-68	51	14	by	by	ADP
cbi-68	51	15	restricting	restrict	VERB
cbi-68	51	16	the	the	DET
cbi-68	51	17	targets	target	NOUN
cbi-68	51	18	of	of	ADP
cbi-68	51	19	mutation	mutation	NOUN
cbi-68	51	20	,	,	PUNCT
cbi-68	51	21	and	and	CCONJ
cbi-68	51	22	that	that	SCONJ
cbi-68	51	23	the	the	DET
cbi-68	51	24	shortest	short	ADJ
cbi-68	51	25	mutational	mutational	ADJ
cbi-68	51	26	targets	target	NOUN
cbi-68	51	27	are	be	AUX
cbi-68	51	28	contained	contain	VERB
cbi-68	51	29	within	within	ADP
cbi-68	51	30	this	this	DET
cbi-68	51	31	restricted	restrict	VERB
cbi-68	51	32	space	space	NOUN
cbi-68	51	33	,	,	PUNCT
cbi-68	51	34	then	then	ADV
cbi-68	51	35	a	a	DET
cbi-68	51	36	simplified	simplified	ADJ
cbi-68	51	37	calculation	calculation	NOUN
cbi-68	51	38	can	can	AUX
cbi-68	51	39	be	be	AUX
cbi-68	51	40	used	use	VERB
cbi-68	51	41	based	base	VERB
cbi-68	51	42	on	on	ADP
cbi-68	51	43	the	the	DET
cbi-68	51	44	size	size	NOUN
cbi-68	51	45	of	of	ADP
cbi-68	51	46	the	the	DET
cbi-68	51	47	genome	genome	NOUN
cbi-68	51	48	,	,	PUNCT
cbi-68	51	49	the	the	DET
cbi-68	51	50	size	size	NOUN
cbi-68	51	51	of	of	ADP
cbi-68	51	52	the	the	DET
cbi-68	51	53	restricted	restricted	ADJ
cbi-68	51	54	mutational	mutational	ADJ
cbi-68	51	55	space	space	NOUN
cbi-68	51	56	and	and	CCONJ
cbi-68	51	57	the	the	DET
cbi-68	51	58	number	number	NOUN
cbi-68	51	59	of	of	ADP
cbi-68	51	60	mutations	mutation	NOUN
cbi-68	51	61	required	require	VERB
cbi-68	51	62	to	to	PART
cbi-68	51	63	hit	hit	VERB
cbi-68	51	64	a	a	DET
cbi-68	51	65	target	target	NOUN
cbi-68	51	66	.	.	PUNCT
cbi-68	52	1	some	some	PRON
cbi-68	52	2	have	have	AUX
cbi-68	52	3	called	call	VERB
cbi-68	52	4	into	into	ADP
cbi-68	52	5	question	question	NOUN
cbi-68	52	6	whether	whether	SCONJ
cbi-68	52	7	or	or	CCONJ
cbi-68	52	8	not	not	PART
cbi-68	52	9	the	the	DET
cbi-68	52	10	somatic	somatic	ADJ
cbi-68	52	11	hypermutation	hypermutation	NOUN
cbi-68	52	12	process	process	NOUN
cbi-68	52	13	actually	actually	ADV
cbi-68	52	14	fits	fit	VERB
cbi-68	52	15	the	the	DET
cbi-68	52	16	given	give	VERB
cbi-68	52	17	criteria	criterion	NOUN
cbi-68	52	18	.	.	PUNCT
cbi-68	53	1	for	for	ADP
cbi-68	53	2	instance	instance	NOUN
cbi-68	53	3	,	,	PUNCT
cbi-68	53	4	there	there	PRON
cbi-68	53	5	is	be	VERB
cbi-68	53	6	evidence	evidence	NOUN
cbi-68	53	7	that	that	SCONJ
cbi-68	53	8	sometimes	sometimes	ADV
cbi-68	53	9	activation	activation	NOUN
cbi-68	53	10	-	-	PUNCT
cbi-68	53	11	induced	induce	VERB
cbi-68	53	12	deaminase	deaminase	NOUN
cbi-68	53	13	(	(	PUNCT
cbi-68	53	14	aid	aid	NOUN
cbi-68	53	15	)	)	PUNCT
cbi-68	53	16	,	,	PUNCT
cbi-68	53	17	the	the	DET
cbi-68	53	18	mechanism	mechanism	NOUN
cbi-68	53	19	behind	behind	ADP
cbi-68	53	20	somatic	somatic	ADJ
cbi-68	53	21	hypermutation	hypermutation	NOUN
cbi-68	53	22	,	,	PUNCT
cbi-68	53	23	sometimes	sometimes	ADV
cbi-68	53	24	hits	hit	VERB
cbi-68	53	25	targets	target	NOUN
cbi-68	53	26	outside	outside	ADP
cbi-68	53	27	of	of	ADP
cbi-68	53	28	the	the	DET
cbi-68	53	29	space	space	NOUN
cbi-68	53	30	suggested	suggest	VERB
cbi-68	53	31	by	by	ADP
cbi-68	53	32	this	this	DET
cbi-68	53	33	characterization	characterization	NOUN
cbi-68	53	34	(	(	PUNCT
cbi-68	53	35	see	see	VERB
cbi-68	53	36	,	,	PUNCT
cbi-68	53	37	for	for	ADP
cbi-68	53	38	instance	instance	NOUN
cbi-68	53	39	,	,	PUNCT
cbi-68	53	40	álvarez	álvarez	PROPN
cbi-68	53	41	-	-	PUNCT
cbi-68	53	42	prado	prado	PROPN
cbi-68	53	43	et	et	PROPN
cbi-68	53	44	al	al	PROPN
cbi-68	53	45	.	.	PROPN
cbi-68	54	1	(	(	PUNCT
cbi-68	54	2	2018	2018	NUM
cbi-68	54	3	)	)	PUNCT
cbi-68	54	4	)	)	PUNCT
cbi-68	54	5	.	.	PUNCT
cbi-68	55	1	what	what	PRON
cbi-68	55	2	is	be	AUX
cbi-68	55	3	at	at	ADP
cbi-68	55	4	issue	issue	NOUN
cbi-68	55	5	is	be	AUX
cbi-68	55	6	not	not	PART
cbi-68	55	7	the	the	DET
cbi-68	55	8	relevance	relevance	NOUN
cbi-68	55	9	of	of	ADP
cbi-68	55	10	the	the	DET
cbi-68	55	11	simplified	simplified	ADJ
cbi-68	55	12	formulas	formula	NOUN
cbi-68	55	13	to	to	ADP
cbi-68	55	14	situations	situation	NOUN
cbi-68	55	15	matching	match	VERB
cbi-68	55	16	the	the	DET
cbi-68	55	17	criteria	criterion	NOUN
cbi-68	55	18	,	,	PUNCT
cbi-68	55	19	but	but	CCONJ
cbi-68	55	20	of	of	ADP
cbi-68	55	21	whether	whether	SCONJ
cbi-68	55	22	or	or	CCONJ
cbi-68	55	23	not	not	PART
cbi-68	55	24	the	the	DET
cbi-68	55	25	specific	specific	ADJ
cbi-68	55	26	case	case	NOUN
cbi-68	55	27	of	of	ADP
cbi-68	55	28	somatic	somatic	ADJ
cbi-68	55	29	mutation	mutation	NOUN
cbi-68	55	30	matches	match	VERB
cbi-68	55	31	the	the	DET
cbi-68	55	32	criteria	criterion	NOUN
cbi-68	55	33	.	.	PUNCT
cbi-68	56	1	additionally	additionally	ADV
cbi-68	56	2	,	,	PUNCT
cbi-68	56	3	the	the	DET
cbi-68	56	4	goal	goal	NOUN
cbi-68	56	5	of	of	ADP
cbi-68	56	6	the	the	DET
cbi-68	56	7	formula	formula	NOUN
cbi-68	56	8	(	(	PUNCT
cbi-68	56	9	and	and	CCONJ
cbi-68	56	10	,	,	PUNCT
cbi-68	56	11	in	in	ADP
cbi-68	56	12	fact	fact	NOUN
cbi-68	56	13	,	,	PUNCT
cbi-68	56	14	any	any	DET
cbi-68	56	15	formula	formula	NOUN
cbi-68	56	16	)	)	PUNCT
cbi-68	56	17	is	be	AUX
cbi-68	56	18	to	to	PART
cbi-68	56	19	generalize	generalize	VERB
cbi-68	56	20	,	,	PUNCT
cbi-68	56	21	so	so	SCONJ
cbi-68	56	22	whether	whether	SCONJ
cbi-68	56	23	or	or	CCONJ
cbi-68	56	24	not	not	PART
cbi-68	56	25	this	this	DET
cbi-68	56	26	criticism	criticism	NOUN
cbi-68	56	27	successfully	successfully	ADV
cbi-68	56	28	prevents	prevent	VERB
cbi-68	56	29	applying	apply	VERB
cbi-68	56	30	the	the	DET
cbi-68	56	31	simplified	simplified	ADJ
cbi-68	56	32	formula	formula	NOUN
cbi-68	56	33	will	will	AUX
cbi-68	56	34	depend	depend	VERB
cbi-68	56	35	on	on	ADP
cbi-68	56	36	the	the	DET
cbi-68	56	37	quantity	quantity	NOUN
cbi-68	56	38	of	of	ADP
cbi-68	56	39	exceptions	exception	NOUN
cbi-68	56	40	.	.	PUNCT
cbi-68	57	1	álvarez	álvarez	NOUN
cbi-68	57	2	-	-	PUNCT
cbi-68	57	3	prado	prado	PROPN
cbi-68	57	4	et	et	PROPN
cbi-68	57	5	al	al	PROPN
cbi-68	57	6	.	.	PROPN
cbi-68	58	1	(	(	PUNCT
cbi-68	58	2	2018	2018	NUM
cbi-68	58	3	)	)	PUNCT
cbi-68	58	4	itself	itself	PRON
cbi-68	58	5	does	do	AUX
cbi-68	58	6	not	not	PART
cbi-68	58	7	specifically	specifically	ADV
cbi-68	58	8	address	address	VERB
cbi-68	58	9	these	these	DET
cbi-68	58	10	issues	issue	NOUN
cbi-68	58	11	,	,	PUNCT
cbi-68	58	12	as	as	SCONJ
cbi-68	58	13	it	it	PRON
cbi-68	58	14	is	be	AUX
cbi-68	58	15	itself	itself	PRON
cbi-68	58	16	working	work	VERB
cbi-68	58	17	with	with	ADP
cbi-68	58	18	a	a	DET
cbi-68	58	19	modified	modify	VERB
cbi-68	58	20	mutational	mutational	ADJ
cbi-68	58	21	process	process	NOUN
cbi-68	58	22	intended	intend	VERB
cbi-68	58	23	to	to	PART
cbi-68	58	24	identify	identify	VERB
cbi-68	58	25	potential	potential	ADJ
cbi-68	58	26	aid	aid	NOUN
cbi-68	58	27	targets	target	NOUN
cbi-68	58	28	from	from	ADP
cbi-68	58	29	a	a	DET
cbi-68	58	30	biochemical	biochemical	ADJ
cbi-68	58	31	perspective	perspective	NOUN
cbi-68	58	32	.	.	PUNCT
cbi-68	59	1	in	in	ADP
cbi-68	59	2	fact	fact	NOUN
cbi-68	59	3	,	,	PUNCT
cbi-68	59	4	the	the	DET
cbi-68	59	5	paper	paper	NOUN
cbi-68	59	6	itself	itself	PRON
cbi-68	59	7	shows	show	VERB
cbi-68	59	8	that	that	SCONJ
cbi-68	59	9	the	the	DET
cbi-68	59	10	mutational	mutational	ADJ
cbi-68	59	11	process	process	NOUN
cbi-68	59	12	with	with	ADP
cbi-68	59	13	all	all	DET
cbi-68	59	14	components	component	NOUN
cbi-68	59	15	intact	intact	ADJ
cbi-68	59	16	actually	actually	ADV
cbi-68	59	17	removes	remove	VERB
cbi-68	59	18	the	the	DET
cbi-68	59	19	vast	vast	ADJ
cbi-68	59	20	majority	majority	NOUN
cbi-68	59	21	of	of	ADP
cbi-68	59	22	“	"	PUNCT
cbi-68	59	23	misses	miss	NOUN
cbi-68	59	24	.	.	PUNCT
cbi-68	59	25	”	"	PUNCT
cbi-68	60	1	the	the	DET
cbi-68	60	2	biochemistry	biochemistry	NOUN
cbi-68	60	3	of	of	ADP
cbi-68	60	4	aid	aid	NOUN
cbi-68	60	5	acting	act	VERB
cbi-68	60	6	alone	alone	ADV
cbi-68	60	7	targets	target	VERB
cbi-68	60	8	a	a	DET
cbi-68	60	9	number	number	NOUN
cbi-68	60	10	of	of	ADP
cbi-68	60	11	regions	region	NOUN
cbi-68	60	12	(	(	PUNCT
cbi-68	60	13	275	275	NUM
cbi-68	60	14	identified	identify	VERB
cbi-68	60	15	by	by	ADP
cbi-68	60	16	the	the	DET
cbi-68	60	17	paper	paper	NOUN
cbi-68	60	18	)	)	PUNCT
cbi-68	60	19	,	,	PUNCT
cbi-68	60	20	but	but	CCONJ
cbi-68	60	21	the	the	DET
cbi-68	60	22	combination	combination	NOUN
cbi-68	60	23	of	of	ADP
cbi-68	60	24	aid	aid	NOUN
cbi-68	60	25	with	with	ADP
cbi-68	60	26	the	the	DET
cbi-68	60	27	other	other	ADJ
cbi-68	60	28	components	component	NOUN
cbi-68	60	29	of	of	ADP
cbi-68	60	30	the	the	DET
cbi-68	60	31	mutational	mutational	ADJ
cbi-68	60	32	process	process	NOUN
cbi-68	60	33	limits	limit	VERB
cbi-68	60	34	the	the	DET
cbi-68	60	35	actual	actual	ADJ
cbi-68	60	36	mutated	mutate	VERB
cbi-68	60	37	targets	target	NOUN
cbi-68	60	38	(	(	PUNCT
cbi-68	60	39	i.e.	i.e.	X
cbi-68	60	40	,	,	PUNCT
cbi-68	60	41	targets	target	NOUN
cbi-68	60	42	with	with	ADP
cbi-68	60	43	an	an	DET
cbi-68	60	44	actual	actual	ADJ
cbi-68	60	45	final	final	ADJ
cbi-68	60	46	sequence	sequence	NOUN
cbi-68	60	47	change	change	NOUN
cbi-68	60	48	)	)	PUNCT
cbi-68	60	49	to	to	ADP
cbi-68	60	50	only	only	ADV
cbi-68	60	51	a	a	DET
cbi-68	60	52	handful	handful	NOUN
cbi-68	60	53	(	(	PUNCT
cbi-68	60	54	liu	liu	PROPN
cbi-68	60	55	et	et	PROPN
cbi-68	60	56	al	al	PROPN
cbi-68	60	57	.	.	PROPN
cbi-68	60	58	,	,	PUNCT
cbi-68	60	59	2008	2008	NUM
cbi-68	60	60	)	)	PUNCT
cbi-68	60	61	.	.	PUNCT
cbi-68	61	1	since	since	SCONJ
cbi-68	61	2	the	the	DET
cbi-68	61	3	mathematics	mathematic	NOUN
cbi-68	61	4	of	of	ADP
cbi-68	61	5	the	the	DET
cbi-68	61	6	process	process	NOUN
cbi-68	61	7	are	be	AUX
cbi-68	61	8	based	base	VERB
cbi-68	61	9	on	on	ADP
cbi-68	61	10	orderof	orderof	NOUN
cbi-68	61	11	-	-	PUNCT
cbi-68	61	12	magnitude	magnitude	NOUN
cbi-68	61	13	reductions	reduction	NOUN
cbi-68	61	14	in	in	ADP
cbi-68	61	15	search	search	NOUN
cbi-68	61	16	space	space	NOUN
cbi-68	61	17	,	,	PUNCT
cbi-68	61	18	it	it	PRON
cbi-68	61	19	is	be	AUX
cbi-68	61	20	unlikely	unlikely	ADJ
cbi-68	61	21	that	that	SCONJ
cbi-68	61	22	having	have	VERB
cbi-68	61	23	a	a	DET
cbi-68	61	24	handful	handful	NOUN
cbi-68	61	25	of	of	ADP
cbi-68	61	26	additional	additional	ADJ
cbi-68	61	27	targets	target	NOUN
cbi-68	61	28	would	would	AUX
cbi-68	61	29	actually	actually	ADV
cbi-68	61	30	significantly	significantly	ADV
cbi-68	61	31	change	change	VERB
cbi-68	61	32	the	the	DET
cbi-68	61	33	results	result	NOUN
cbi-68	61	34	,	,	PUNCT
cbi-68	61	35	especially	especially	ADV
cbi-68	61	36	if	if	SCONJ
cbi-68	61	37	they	they	PRON
cbi-68	61	38	occurred	occur	VERB
cbi-68	61	39	at	at	ADP
cbi-68	61	40	a	a	DET
cbi-68	61	41	lower	low	ADJ
cbi-68	61	42	frequency	frequency	NOUN
cbi-68	61	43	than	than	ADP
cbi-68	61	44	those	those	PRON
cbi-68	61	45	in	in	ADP
cbi-68	61	46	the	the	DET
cbi-68	61	47	primary	primary	ADJ
cbi-68	61	48	targeted	target	VERB
cbi-68	61	49	area	area	NOUN
cbi-68	61	50	.	.	PUNCT
cbi-68	62	1	thus	thus	ADV
cbi-68	62	2	,	,	PUNCT
cbi-68	62	3	while	while	SCONJ
cbi-68	62	4	it	it	PRON
cbi-68	62	5	is	be	AUX
cbi-68	62	6	certainly	certainly	ADV
cbi-68	62	7	possible	possible	ADJ
cbi-68	62	8	to	to	PART
cbi-68	62	9	be	be	AUX
cbi-68	62	10	more	more	ADV
cbi-68	62	11	precise	precise	ADJ
cbi-68	62	12	in	in	ADP
cbi-68	62	13	the	the	DET
cbi-68	62	14	measuring	measuring	NOUN
cbi-68	62	15	of	of	ADP
cbi-68	62	16	active	active	ADJ
cbi-68	62	17	information	information	NOUN
cbi-68	62	18	of	of	ADP
cbi-68	62	19	somatic	somatic	ADJ
cbi-68	62	20	hypermutation	hypermutation	NOUN
cbi-68	62	21	,	,	PUNCT
cbi-68	62	22	46	46	NUM
cbi-68	62	23	letters	letter	NOUN
cbi-68	62	24	and	and	CCONJ
cbi-68	62	25	notes	note	NOUN
cbi-68	62	26	it	it	PRON
cbi-68	62	27	seems	seem	VERB
cbi-68	62	28	that	that	SCONJ
cbi-68	62	29	being	be	AUX
cbi-68	62	30	used	use	VERB
cbi-68	62	31	as	as	ADP
cbi-68	62	32	a	a	DET
cbi-68	62	33	simplified	simplified	ADJ
cbi-68	62	34	measurement	measurement	NOUN
cbi-68	62	35	is	be	AUX
cbi-68	62	36	still	still	ADV
cbi-68	62	37	well	well	ADV
cbi-68	62	38	-	-	PUNCT
cbi-68	62	39	justified	justify	VERB
cbi-68	62	40	.	.	PUNCT
cbi-68	63	1	in	in	ADP
cbi-68	63	2	fact	fact	NOUN
cbi-68	63	3	,	,	PUNCT
cbi-68	63	4	such	such	ADJ
cbi-68	63	5	papers	paper	NOUN
cbi-68	63	6	as	as	ADP
cbi-68	63	7	álvarez	álvarez	NOUN
cbi-68	63	8	-	-	PUNCT
cbi-68	63	9	prado	prado	PROPN
cbi-68	63	10	et	et	PROPN
cbi-68	63	11	al	al	PROPN
cbi-68	63	12	.	.	PROPN
cbi-68	64	1	(	(	PUNCT
cbi-68	64	2	2018	2018	NUM
cbi-68	64	3	)	)	PUNCT
cbi-68	64	4	show	show	VERB
cbi-68	64	5	how	how	SCONJ
cbi-68	64	6	important	important	ADJ
cbi-68	64	7	the	the	DET
cbi-68	64	8	targeting	targeting	NOUN
cbi-68	64	9	is	be	AUX
cbi-68	64	10	(	(	PUNCT
cbi-68	64	11	justifying	justify	VERB
cbi-68	64	12	the	the	DET
cbi-68	64	13	criteria	criterion	NOUN
cbi-68	64	14	for	for	ADP
cbi-68	64	15	using	use	VERB
cbi-68	64	16	the	the	DET
cbi-68	64	17	formula	formula	NOUN
cbi-68	64	18	)	)	PUNCT
cbi-68	64	19	,	,	PUNCT
cbi-68	64	20	by	by	ADP
cbi-68	64	21	showing	show	VERB
cbi-68	64	22	the	the	DET
cbi-68	64	23	prevalence	prevalence	NOUN
cbi-68	64	24	of	of	ADP
cbi-68	64	25	cancerous	cancerous	ADJ
cbi-68	64	26	e!ects	e!ect	NOUN
cbi-68	64	27	of	of	ADP
cbi-68	64	28	mistargeted	mistargete	VERB
cbi-68	64	29	mutations	mutation	NOUN
cbi-68	64	30	.	.	PUNCT
cbi-68	65	1	is	be	AUX
cbi-68	65	2	n’t	not	PART
cbi-68	65	3	this	this	PRON
cbi-68	65	4	already	already	ADV
cbi-68	65	5	well	well	ADV
cbi-68	65	6	-	-	PUNCT
cbi-68	65	7	known	know	VERB
cbi-68	65	8	?	?	PUNCT
cbi-68	66	1	one	one	NUM
cbi-68	66	2	criticism	criticism	NOUN
cbi-68	66	3	is	be	AUX
cbi-68	66	4	that	that	SCONJ
cbi-68	66	5	we	we	PRON
cbi-68	66	6	already	already	ADV
cbi-68	66	7	knew	know	VERB
cbi-68	66	8	that	that	SCONJ
cbi-68	66	9	there	there	PRON
cbi-68	66	10	are	be	VERB
cbi-68	66	11	targeted	target	VERB
cbi-68	66	12	mutations	mutation	NOUN
cbi-68	66	13	without	without	ADP
cbi-68	66	14	active	active	ADJ
cbi-68	66	15	information	information	NOUN
cbi-68	66	16	.	.	PUNCT
cbi-68	67	1	this	this	PRON
cbi-68	67	2	is	be	AUX
cbi-68	67	3	at	at	ADP
cbi-68	67	4	least	least	ADJ
cbi-68	67	5	partially	partially	ADV
cbi-68	67	6	true	true	ADJ
cbi-68	67	7	.	.	PUNCT
cbi-68	68	1	while	while	SCONJ
cbi-68	68	2	there	there	PRON
cbi-68	68	3	are	be	VERB
cbi-68	68	4	groups	group	NOUN
cbi-68	68	5	who	who	PRON
cbi-68	68	6	recognize	recognize	VERB
cbi-68	68	7	this	this	DET
cbi-68	68	8	reality	reality	NOUN
cbi-68	68	9	,	,	PUNCT
cbi-68	68	10	many	many	ADJ
cbi-68	68	11	evolutionary	evolutionary	ADJ
cbi-68	68	12	biologists	biologist	NOUN
cbi-68	68	13	do	do	VERB
cbi-68	68	14	not	not	PART
cbi-68	68	15	.	.	PUNCT
cbi-68	69	1	in	in	ADP
cbi-68	69	2	fact	fact	NOUN
cbi-68	69	3	,	,	PUNCT
cbi-68	69	4	i	i	PRON
cbi-68	69	5	’ve	’ve	AUX
cbi-68	69	6	talked	talk	VERB
cbi-68	69	7	with	with	ADP
cbi-68	69	8	several	several	ADJ
cbi-68	69	9	practicing	practice	VERB
cbi-68	69	10	biologists	biologist	NOUN
cbi-68	69	11	(	(	PUNCT
cbi-68	69	12	evolutionary	evolutionary	ADJ
cbi-68	69	13	,	,	PUNCT
cbi-68	69	14	molecular	molecular	ADJ
cbi-68	69	15	,	,	PUNCT
cbi-68	69	16	and	and	CCONJ
cbi-68	69	17	otherwise	otherwise	ADV
cbi-68	69	18	)	)	PUNCT
cbi-68	69	19	who	who	PRON
cbi-68	69	20	were	be	AUX
cbi-68	69	21	shocked	shock	VERB
cbi-68	69	22	to	to	PART
cbi-68	69	23	find	find	VERB
cbi-68	69	24	out	out	ADP
cbi-68	69	25	even	even	ADV
cbi-68	69	26	that	that	SCONJ
cbi-68	69	27	such	such	ADJ
cbi-68	69	28	phenomena	phenomenon	NOUN
cbi-68	69	29	existed	exist	VERB
cbi-68	69	30	.	.	PUNCT
cbi-68	70	1	some	some	PRON
cbi-68	70	2	were	be	AUX
cbi-68	70	3	familiar	familiar	ADJ
cbi-68	70	4	with	with	ADP
cbi-68	70	5	somatic	somatic	ADJ
cbi-68	70	6	hypermutation	hypermutation	NOUN
cbi-68	70	7	as	as	ADP
cbi-68	70	8	a	a	DET
cbi-68	70	9	general	general	ADJ
cbi-68	70	10	idea	idea	NOUN
cbi-68	70	11	,	,	PUNCT
cbi-68	70	12	but	but	CCONJ
cbi-68	70	13	had	have	AUX
cbi-68	70	14	not	not	PART
cbi-68	70	15	mentally	mentally	ADV
cbi-68	70	16	linked	link	VERB
cbi-68	70	17	it	it	PRON
cbi-68	70	18	to	to	ADP
cbi-68	70	19	the	the	DET
cbi-68	70	20	question	question	NOUN
cbi-68	70	21	of	of	ADP
cbi-68	70	22	directed	direct	VERB
cbi-68	70	23	mutation	mutation	NOUN
cbi-68	70	24	.	.	PUNCT
cbi-68	71	1	many	many	ADJ
cbi-68	71	2	biologists	biologist	NOUN
cbi-68	71	3	still	still	ADV
cbi-68	71	4	believe	believe	VERB
cbi-68	71	5	(	(	PUNCT
cbi-68	71	6	and	and	CCONJ
cbi-68	71	7	most	most	ADJ
cbi-68	71	8	textbooks	textbook	NOUN
cbi-68	71	9	still	still	ADV
cbi-68	71	10	teach	teach	VERB
cbi-68	71	11	)	)	PUNCT
cbi-68	71	12	that	that	SCONJ
cbi-68	71	13	mutations	mutation	NOUN
cbi-68	71	14	are	be	AUX
cbi-68	71	15	uncorrelated	uncorrelated	ADJ
cbi-68	71	16	with	with	ADP
cbi-68	71	17	their	their	PRON
cbi-68	71	18	fitness	fitness	NOUN
cbi-68	71	19	e!ects	e!ect	NOUN
cbi-68	71	20	.	.	PUNCT
cbi-68	72	1	this	this	PRON
cbi-68	72	2	could	could	AUX
cbi-68	72	3	wind	wind	VERB
cbi-68	72	4	up	up	ADP
cbi-68	72	5	being	be	AUX
cbi-68	72	6	true	true	ADJ
cbi-68	72	7	or	or	CCONJ
cbi-68	72	8	false	false	ADJ
cbi-68	72	9	in	in	ADP
cbi-68	72	10	the	the	DET
cbi-68	72	11	general	general	ADJ
cbi-68	72	12	case	case	NOUN
cbi-68	72	13	.	.	PUNCT
cbi-68	73	1	active	active	ADJ
cbi-68	73	2	information	information	NOUN
cbi-68	73	3	provides	provide	VERB
cbi-68	73	4	a	a	DET
cbi-68	73	5	mechanism	mechanism	NOUN
cbi-68	73	6	for	for	ADP
cbi-68	73	7	measuring	measure	VERB
cbi-68	73	8	this	this	DET
cbi-68	73	9	question	question	NOUN
cbi-68	73	10	from	from	ADP
cbi-68	73	11	the	the	DET
cbi-68	73	12	data	datum	NOUN
cbi-68	73	13	.	.	PUNCT
cbi-68	74	1	however	however	ADV
cbi-68	74	2	,	,	PUNCT
cbi-68	74	3	the	the	DET
cbi-68	74	4	more	more	ADV
cbi-68	74	5	important	important	ADJ
cbi-68	74	6	goal	goal	NOUN
cbi-68	74	7	is	be	AUX
cbi-68	74	8	not	not	PART
cbi-68	74	9	to	to	PART
cbi-68	74	10	determine	determine	VERB
cbi-68	74	11	the	the	DET
cbi-68	74	12	existence	existence	NOUN
cbi-68	74	13	of	of	ADP
cbi-68	74	14	such	such	ADJ
cbi-68	74	15	phenomena	phenomenon	NOUN
cbi-68	74	16	,	,	PUNCT
cbi-68	74	17	but	but	CCONJ
cbi-68	74	18	rather	rather	ADV
cbi-68	74	19	to	to	PART
cbi-68	74	20	be	be	AUX
cbi-68	74	21	able	able	ADJ
cbi-68	74	22	to	to	PART
cbi-68	74	23	measure	measure	VERB
cbi-68	74	24	the	the	DET
cbi-68	74	25	phenomena	phenomenon	NOUN
cbi-68	74	26	.	.	PUNCT
cbi-68	75	1	currently	currently	ADV
cbi-68	75	2	,	,	PUNCT
cbi-68	75	3	directed	direct	VERB
cbi-68	75	4	mutations	mutation	NOUN
cbi-68	75	5	are	be	AUX
cbi-68	75	6	only	only	ADV
cbi-68	75	7	known	know	VERB
cbi-68	75	8	after	after	SCONJ
cbi-68	75	9	we	we	PRON
cbi-68	75	10	know	know	VERB
cbi-68	75	11	the	the	DET
cbi-68	75	12	mechanism	mechanism	NOUN
cbi-68	75	13	in	in	ADP
cbi-68	75	14	detail	detail	NOUN
cbi-68	75	15	.	.	PUNCT
cbi-68	76	1	the	the	DET
cbi-68	76	2	goal	goal	NOUN
cbi-68	76	3	of	of	ADP
cbi-68	76	4	active	active	ADJ
cbi-68	76	5	information	information	NOUN
cbi-68	76	6	is	be	AUX
cbi-68	76	7	to	to	PART
cbi-68	76	8	provide	provide	VERB
cbi-68	76	9	a	a	DET
cbi-68	76	10	measurement	measurement	NOUN
cbi-68	76	11	prior	prior	ADV
cbi-68	76	12	to	to	ADP
cbi-68	76	13	knowing	know	VERB
cbi-68	76	14	the	the	DET
cbi-68	76	15	mechanism	mechanism	NOUN
cbi-68	76	16	(	(	PUNCT
cbi-68	76	17	in	in	ADP
cbi-68	76	18	fact	fact	NOUN
cbi-68	76	19	,	,	PUNCT
cbi-68	76	20	specifically	specifically	ADV
cbi-68	76	21	to	to	PART
cbi-68	76	22	see	see	VERB
cbi-68	76	23	if	if	SCONJ
cbi-68	76	24	there	there	PRON
cbi-68	76	25	is	be	VERB
cbi-68	76	26	a	a	DET
cbi-68	76	27	mechanism	mechanism	NOUN
cbi-68	76	28	worth	worth	ADJ
cbi-68	76	29	finding	finding	NOUN
cbi-68	76	30	)	)	PUNCT
cbi-68	76	31	.	.	PUNCT
cbi-68	77	1	there	there	PRON
cbi-68	77	2	are	be	VERB
cbi-68	77	3	some	some	PRON
cbi-68	77	4	who	who	PRON
cbi-68	77	5	agree	agree	VERB
cbi-68	77	6	that	that	SCONJ
cbi-68	77	7	mutations	mutation	NOUN
cbi-68	77	8	are	be	AUX
cbi-68	77	9	not	not	PART
cbi-68	77	10	uncorrelated	uncorrelate	VERB
cbi-68	77	11	with	with	ADP
cbi-68	77	12	fitness	fitness	NOUN
cbi-68	77	13	,	,	PUNCT
cbi-68	77	14	but	but	CCONJ
cbi-68	77	15	do	do	AUX
cbi-68	77	16	n’t	not	PART
cbi-68	77	17	believe	believe	VERB
cbi-68	77	18	that	that	SCONJ
cbi-68	77	19	comparing	compare	VERB
cbi-68	77	20	against	against	ADP
cbi-68	77	21	a	a	DET
cbi-68	77	22	random	random	ADJ
cbi-68	77	23	background	background	NOUN
cbi-68	77	24	is	be	AUX
cbi-68	77	25	a	a	DET
cbi-68	77	26	correct	correct	ADJ
cbi-68	77	27	way	way	NOUN
cbi-68	77	28	to	to	PART
cbi-68	77	29	quantify	quantify	VERB
cbi-68	77	30	the	the	DET
cbi-68	77	31	phenomena	phenomenon	NOUN
cbi-68	77	32	.	.	PUNCT
cbi-68	78	1	however	however	ADV
cbi-68	78	2	,	,	PUNCT
cbi-68	78	3	i	i	PRON
cbi-68	78	4	have	have	AUX
cbi-68	78	5	not	not	PART
cbi-68	78	6	heard	hear	VERB
cbi-68	78	7	any	any	DET
cbi-68	78	8	such	such	ADJ
cbi-68	78	9	critic	critic	NOUN
cbi-68	78	10	present	present	VERB
cbi-68	78	11	an	an	DET
cbi-68	78	12	alternative	alternative	ADJ
cbi-68	78	13	means	mean	NOUN
cbi-68	78	14	of	of	ADP
cbi-68	78	15	quantifying	quantify	VERB
cbi-68	78	16	directedness	directedness	NOUN
cbi-68	78	17	.	.	PUNCT
cbi-68	79	1	i	i	PRON
cbi-68	79	2	think	think	VERB
cbi-68	79	3	the	the	DET
cbi-68	79	4	mathematics	mathematic	NOUN
cbi-68	79	5	of	of	ADP
cbi-68	79	6	active	active	ADJ
cbi-68	79	7	information	information	NOUN
cbi-68	79	8	(	(	PUNCT
cbi-68	79	9	and	and	CCONJ
cbi-68	79	10	the	the	DET
cbi-68	79	11	biological	biological	ADJ
cbi-68	79	12	application	application	NOUN
cbi-68	79	13	of	of	ADP
cbi-68	79	14	it	it	PRON
cbi-68	79	15	)	)	PUNCT
cbi-68	79	16	is	be	AUX
cbi-68	79	17	su"ciently	su"ciently	ADV
cbi-68	79	18	sound	sound	ADJ
cbi-68	79	19	for	for	ADP
cbi-68	79	20	experimental	experimental	ADJ
cbi-68	79	21	use	use	NOUN
cbi-68	79	22	.	.	PUNCT
cbi-68	80	1	however	however	ADV
cbi-68	80	2	,	,	PUNCT
cbi-68	80	3	if	if	SCONJ
cbi-68	80	4	there	there	PRON
cbi-68	80	5	is	be	VERB
cbi-68	80	6	a	a	DET
cbi-68	80	7	better	well	ADJ
cbi-68	80	8	means	mean	NOUN
cbi-68	80	9	of	of	ADP
cbi-68	80	10	quantification	quantification	NOUN
cbi-68	80	11	,	,	PUNCT
cbi-68	80	12	i	i	PRON
cbi-68	80	13	would	would	AUX
cbi-68	80	14	be	be	AUX
cbi-68	80	15	interested	interested	ADJ
cbi-68	80	16	in	in	ADP
cbi-68	80	17	comparing	compare	VERB
cbi-68	80	18	the	the	DET
cbi-68	80	19	two	two	NUM
cbi-68	80	20	.	.	PUNCT
cbi-68	81	1	additional	additional	ADJ
cbi-68	81	2	notes	note	VERB
cbi-68	81	3	the	the	DET
cbi-68	81	4	mathematics	mathematic	NOUN
cbi-68	81	5	of	of	ADP
cbi-68	81	6	bartlett	bartlett	PROPN
cbi-68	81	7	(	(	PUNCT
cbi-68	81	8	2020	2020	NUM
cbi-68	81	9	)	)	PUNCT
cbi-68	81	10	are	be	AUX
cbi-68	81	11	a	a	DET
cbi-68	81	12	little	little	ADJ
cbi-68	81	13	hard	hard	ADJ
cbi-68	81	14	to	to	PART
cbi-68	81	15	follow	follow	VERB
cbi-68	81	16	,	,	PUNCT
cbi-68	81	17	so	so	CCONJ
cbi-68	81	18	i	i	PRON
cbi-68	81	19	wanted	want	VERB
cbi-68	81	20	to	to	PART
cbi-68	81	21	present	present	VERB
cbi-68	81	22	a	a	DET
cbi-68	81	23	combined	combine	VERB
cbi-68	81	24	formula	formula	NOUN
cbi-68	81	25	here	here	ADV
cbi-68	81	26	.	.	PUNCT
cbi-68	82	1	the	the	DET
cbi-68	82	2	meanings	meaning	NOUN
cbi-68	82	3	of	of	ADP
cbi-68	82	4	the	the	DET
cbi-68	82	5	components	component	NOUN
cbi-68	82	6	of	of	ADP
cbi-68	82	7	the	the	DET
cbi-68	82	8	formula	formula	NOUN
cbi-68	82	9	are	be	AUX
cbi-68	82	10	given	give	VERB
cbi-68	82	11	in	in	ADP
cbi-68	82	12	bartlett	bartlett	PROPN
cbi-68	82	13	(	(	PUNCT
cbi-68	82	14	2020	2020	NUM
cbi-68	82	15	)	)	PUNCT
cbi-68	82	16	.	.	PUNCT
cbi-68	82	17	!	!	PUNCT
cbi-68	83	1	+	+	ADJ
cbi-68	83	2	max	max	NOUN
cbi-68	83	3	=	=	PROPN
cbi-68	83	4	log2	log2	PROPN
cbi-68	83	5	!	!	PUNCT
cbi-68	84	1	"	"	PUNCT
cbi-68	84	2	!	!	PUNCT
cbi-68	85	1	1	1	NUM
cbi-68	85	2	#	#	NOUN
cbi-68	85	3	!	!	NOUN
cbi-68	85	4	1	1	NUM
cbi-68	85	5	"	"	PUNCT
cbi-68	85	6	!	!	PUNCT
cbi-68	86	1	log2	log2	PROPN
cbi-68	86	2	#	#	SYM
cbi-68	86	3	$	$	SYM
cbi-68	86	4	%	%	NOUN
cbi-68	86	5	"	"	PUNCT
cbi-68	86	6	!	!	PUNCT
cbi-68	86	7	2	2	NUM
cbi-68	86	8	#	#	NOUN
cbi-68	86	9	!	!	NOUN
cbi-68	86	10	2	2	NUM
cbi-68	86	11	!	!	PUNCT
cbi-68	87	1	"	"	PUNCT
cbi-68	87	2	!	!	PUNCT
cbi-68	88	1	1	1	NUM
cbi-68	88	2	#	#	NOUN
cbi-68	88	3	!	!	NOUN
cbi-68	88	4	1	1	NUM
cbi-68	88	5	(	(	PUNCT
cbi-68	88	6	1	1	NUM
cbi-68	88	7	!	!	PUNCT
cbi-68	88	8	$	$	SYM
cbi-68	88	9	!	!	PUNCT
cbi-68	88	10	)	)	PUNCT
cbi-68	88	11	!	!	PUNCT
cbi-68	89	1	$	$	SYM
cbi-68	89	2	$	$	SYM
cbi-68	89	3	$	$	SYM
cbi-68	89	4	!	!	PUNCT
cbi-68	90	1	$	$	X
cbi-68	90	2	!	!	PUNCT
cbi-68	91	1	(	(	PUNCT
cbi-68	91	2	1	1	NUM
cbi-68	91	3	!	!	SYM
cbi-68	91	4	$	$	SYM
cbi-68	91	5	$	$	NUM
cbi-68	91	6	)	)	PUNCT
cbi-68	91	7	&	&	CCONJ
cbi-68	91	8	'	'	PUNCT
cbi-68	91	9	(	(	PUNCT
cbi-68	91	10	(	(	PUNCT
cbi-68	91	11	1	1	NUM
cbi-68	91	12	)	)	PUNCT
cbi-68	91	13	!	!	PUNCT
cbi-68	92	1	+	+	NOUN
cbi-68	92	2	min	min	NOUN
cbi-68	92	3	=	=	NOUN
cbi-68	92	4	log2	log2	PROPN
cbi-68	92	5	!	!	PUNCT
cbi-68	93	1	"	"	PUNCT
cbi-68	93	2	!	!	PUNCT
cbi-68	94	1	1	1	NUM
cbi-68	94	2	#	#	NOUN
cbi-68	94	3	!	!	NOUN
cbi-68	94	4	1	1	NUM
cbi-68	94	5	"	"	PUNCT
cbi-68	94	6	!	!	PUNCT
cbi-68	95	1	log2	log2	PROPN
cbi-68	95	2	#	#	SYM
cbi-68	95	3	$	$	SYM
cbi-68	95	4	%	%	NOUN
cbi-68	95	5	"	"	PUNCT
cbi-68	95	6	!	!	PUNCT
cbi-68	95	7	2	2	NUM
cbi-68	95	8	#	#	NOUN
cbi-68	95	9	!	!	NOUN
cbi-68	95	10	2	2	NUM
cbi-68	95	11	!	!	PUNCT
cbi-68	96	1	"	"	PUNCT
cbi-68	96	2	!	!	PUNCT
cbi-68	97	1	1	1	NUM
cbi-68	97	2	#	#	NOUN
cbi-68	97	3	!	!	NOUN
cbi-68	97	4	1	1	NUM
cbi-68	97	5	(	(	PUNCT
cbi-68	97	6	1	1	NUM
cbi-68	97	7	!	!	PUNCT
cbi-68	97	8	$	$	SYM
cbi-68	97	9	!	!	PUNCT
cbi-68	97	10	)	)	PUNCT
cbi-68	98	1	$	$	SYM
cbi-68	98	2	!	!	PUNCT
cbi-68	99	1	(	(	PUNCT
cbi-68	99	2	1	1	NUM
cbi-68	99	3	!	!	SYM
cbi-68	99	4	$	$	SYM
cbi-68	99	5	$	$	NUM
cbi-68	99	6	)	)	PUNCT
cbi-68	99	7	&	&	CCONJ
cbi-68	99	8	'	'	PUNCT
cbi-68	99	9	(	(	PUNCT
cbi-68	99	10	(	(	PUNCT
cbi-68	99	11	2	2	NUM
cbi-68	99	12	)	)	PUNCT
cbi-68	99	13	additionally	additionally	ADV
cbi-68	99	14	,	,	PUNCT
cbi-68	99	15	a	a	DET
cbi-68	99	16	supplementary	supplementary	ADJ
cbi-68	99	17	spreadsheet	spreadsheet	NOUN
cbi-68	99	18	to	to	PART
cbi-68	99	19	assist	assist	VERB
cbi-68	99	20	calculating	calculate	VERB
cbi-68	99	21	active	active	ADJ
cbi-68	99	22	information	information	NOUN
cbi-68	99	23	using	use	VERB
cbi-68	99	24	the	the	DET
cbi-68	99	25	techniques	technique	NOUN
cbi-68	99	26	found	find	VERB
cbi-68	99	27	in	in	ADP
cbi-68	99	28	the	the	DET
cbi-68	99	29	paper	paper	NOUN
cbi-68	99	30	is	be	AUX
cbi-68	99	31	available	available	ADJ
cbi-68	99	32	(	(	PUNCT
cbi-68	99	33	supplement	supplement	NOUN
cbi-68	99	34	1	1	NUM
cbi-68	99	35	)	)	PUNCT
cbi-68	99	36	,	,	PUNCT
cbi-68	99	37	with	with	ADP
cbi-68	99	38	example	example	NOUN
cbi-68	99	39	possibilities	possibility	NOUN
cbi-68	99	40	provided	provide	VERB
cbi-68	99	41	to	to	PART
cbi-68	99	42	give	give	VERB
cbi-68	99	43	a	a	DET
cbi-68	99	44	feel	feel	NOUN
cbi-68	99	45	for	for	ADP
cbi-68	99	46	how	how	SCONJ
cbi-68	99	47	di!erent	di!erent	NOUN
cbi-68	99	48	outcomes	outcome	NOUN
cbi-68	99	49	a!ect	a!ect	PROPN
cbi-68	99	50	active	active	ADJ
cbi-68	99	51	information.1	information.1	PROPN
cbi-68	99	52	álvarez	álvarez	NOUN
cbi-68	99	53	-	-	PUNCT
cbi-68	99	54	prado	prado	PROPN
cbi-68	99	55	,	,	PUNCT
cbi-68	99	56	á	á	X
cbi-68	99	57	f	f	X
cbi-68	99	58	et	et	PROPN
cbi-68	99	59	al	al	PROPN
cbi-68	99	60	.	.	PROPN
cbi-68	100	1	(	(	PUNCT
cbi-68	100	2	2018	2018	NUM
cbi-68	100	3	)	)	PUNCT
cbi-68	100	4	.	.	PUNCT
cbi-68	101	1	“	"	PUNCT
cbi-68	101	2	a	a	DET
cbi-68	101	3	broad	broad	ADJ
cbi-68	101	4	atlas	atlas	NOUN
cbi-68	101	5	of	of	ADP
cbi-68	101	6	somatic	somatic	ADJ
cbi-68	101	7	hypermutation	hypermutation	NOUN
cbi-68	101	8	allows	allow	VERB
cbi-68	101	9	prediction	prediction	NOUN
cbi-68	101	10	of	of	ADP
cbi-68	101	11	activationinduced	activationinduce	VERB
cbi-68	101	12	deaminase	deaminase	NOUN
cbi-68	101	13	targets	target	NOUN
cbi-68	101	14	”	"	PUNCT
cbi-68	101	15	.	.	PUNCT
cbi-68	102	1	in	in	ADP
cbi-68	102	2	:	:	PUNCT
cbi-68	102	3	journal	journal	NOUN
cbi-68	102	4	of	of	ADP
cbi-68	102	5	experimental	experimental	ADJ
cbi-68	102	6	medicine	medicine	NOUN
cbi-68	102	7	215.3	215.3	NUM
cbi-68	102	8	,	,	PUNCT
cbi-68	102	9	pp	pp	ADJ
cbi-68	102	10	.	.	PUNCT
cbi-68	103	1	761–771	761–771	NUM
cbi-68	103	2	.	.	PUNCT
cbi-68	104	1	doi	doi	NOUN
cbi-68	104	2	:	:	PUNCT
cbi-68	104	3	10.1084/	10.1084/	NUM
cbi-68	104	4	jem.20171738	jem.20171738	PROPN
cbi-68	104	5	.	.	PUNCT
cbi-68	105	1	bartlett	bartlett	PROPN
cbi-68	105	2	,	,	PUNCT
cbi-68	105	3	j	j	PROPN
cbi-68	105	4	(	(	PUNCT
cbi-68	105	5	2020	2020	NUM
cbi-68	105	6	)	)	PUNCT
cbi-68	105	7	.	.	PUNCT
cbi-68	106	1	“	"	PUNCT
cbi-68	106	2	measuring	measure	VERB
cbi-68	106	3	active	active	ADJ
cbi-68	106	4	information	information	NOUN
cbi-68	106	5	in	in	ADP
cbi-68	106	6	biological	biological	ADJ
cbi-68	106	7	systems	system	NOUN
cbi-68	106	8	”	"	PUNCT
cbi-68	106	9	.	.	PUNCT
cbi-68	107	1	in	in	ADP
cbi-68	107	2	:	:	PUNCT
cbi-68	107	3	communications	communication	NOUN
cbi-68	107	4	of	of	ADP
cbi-68	107	5	the	the	DET
cbi-68	107	6	blyth	blyth	PROPN
cbi-68	107	7	institute	institute	PROPN
cbi-68	107	8	2020.2	2020.2	NUM
cbi-68	107	9	,	,	PUNCT
cbi-68	107	10	pp	pp	PROPN
cbi-68	107	11	.	.	PUNCT
cbi-68	108	1	1–11	1–11	PROPN
cbi-68	108	2	.	.	PUNCT
cbi-68	109	1	doi	doi	NOUN
cbi-68	109	2	:	:	PUNCT
cbi-68	109	3	doi:10.5048	doi:10.5048	ADJ
cbi-68	109	4	/	/	SYM
cbi-68	109	5	bioc	bioc	ADJ
cbi-68	109	6	.	.	PUNCT
cbi-68	110	1	2020.2	2020.2	NUM
cbi-68	110	2	.	.	PUNCT
cbi-68	110	3	dembski	dembski	NOUN
cbi-68	110	4	,	,	PUNCT
cbi-68	110	5	w	w	PROPN
cbi-68	110	6	a	a	PRON
cbi-68	110	7	and	and	CCONJ
cbi-68	110	8	r	r	PROPN
cbi-68	110	9	j	j	PROPN
cbi-68	110	10	marks	marks	PROPN
cbi-68	110	11	ii	ii	PROPN
cbi-68	110	12	(	(	PUNCT
cbi-68	110	13	2009	2009	NUM
cbi-68	110	14	)	)	PUNCT
cbi-68	110	15	.	.	PUNCT
cbi-68	111	1	“	"	PUNCT
cbi-68	111	2	conservation	conservation	NOUN
cbi-68	111	3	of	of	ADP
cbi-68	111	4	information	information	NOUN
cbi-68	111	5	in	in	ADP
cbi-68	111	6	search	search	NOUN
cbi-68	111	7	:	:	PUNCT
cbi-68	111	8	measuring	measure	VERB
cbi-68	111	9	the	the	DET
cbi-68	111	10	cost	cost	NOUN
cbi-68	111	11	of	of	ADP
cbi-68	111	12	success	success	NOUN
cbi-68	111	13	”	"	PUNCT
cbi-68	111	14	.	.	PUNCT
cbi-68	112	1	in	in	ADP
cbi-68	112	2	:	:	PUNCT
cbi-68	112	3	ieee	ieee	NOUN
cbi-68	112	4	transactions	transaction	NOUN
cbi-68	112	5	on	on	ADP
cbi-68	112	6	systems	system	NOUN
cbi-68	112	7	,	,	PUNCT
cbi-68	112	8	man	man	NOUN
cbi-68	112	9	and	and	CCONJ
cbi-68	112	10	cybernetics	cybernetic	NOUN
cbi-68	112	11	a	a	PRON
cbi-68	112	12	,	,	PUNCT
cbi-68	112	13	systems	system	NOUN
cbi-68	112	14	&	&	CCONJ
cbi-68	112	15	humans	human	NOUN
cbi-68	112	16	5.5	5.5	NUM
cbi-68	112	17	,	,	PUNCT
cbi-68	112	18	pp	pp	ADJ
cbi-68	112	19	.	.	PUNCT
cbi-68	113	1	1051–1061	1051–1061	NUM
cbi-68	113	2	.	.	PUNCT
cbi-68	114	1	doi	doi	NOUN
cbi-68	114	2	:	:	PUNCT
cbi-68	114	3	10.1109	10.1109	NUM
cbi-68	114	4	/	/	SYM
cbi-68	114	5	tsmca.2009.2025027	tsmca.2009.2025027	NOUN
cbi-68	114	6	.	.	PUNCT
cbi-68	115	1	liu	liu	PROPN
cbi-68	115	2	,	,	PUNCT
cbi-68	115	3	m	m	VERB
cbi-68	115	4	et	et	NOUN
cbi-68	115	5	al	al	PROPN
cbi-68	115	6	.	.	PUNCT
cbi-68	115	7	(	(	PUNCT
cbi-68	115	8	2008	2008	NUM
cbi-68	115	9	)	)	PUNCT
cbi-68	115	10	.	.	PUNCT
cbi-68	116	1	“	"	PUNCT
cbi-68	116	2	two	two	NUM
cbi-68	116	3	levels	level	NOUN
cbi-68	116	4	of	of	ADP
cbi-68	116	5	protection	protection	NOUN
cbi-68	116	6	for	for	ADP
cbi-68	116	7	the	the	DET
cbi-68	116	8	b	b	PROPN
cbi-68	116	9	cell	cell	NOUN
cbi-68	116	10	genome	genome	NOUN
cbi-68	116	11	during	during	ADP
cbi-68	116	12	somatic	somatic	ADJ
cbi-68	116	13	hypermutation	hypermutation	NOUN
cbi-68	116	14	”	"	PUNCT
cbi-68	116	15	.	.	PUNCT
cbi-68	117	1	in	in	ADP
cbi-68	117	2	:	:	PUNCT
cbi-68	117	3	nature	nature	NOUN
cbi-68	117	4	451	451	NUM
cbi-68	117	5	,	,	PUNCT
cbi-68	117	6	pp	pp	ADJ
cbi-68	117	7	.	.	PUNCT
cbi-68	118	1	841–846	841–846	NUM
cbi-68	118	2	.	.	PUNCT
cbi-68	118	3	doi	doi	NOUN
cbi-68	118	4	:	:	PUNCT
cbi-68	118	5	10.1038	10.1038	NUM
cbi-68	118	6	/	/	SYM
cbi-68	118	7	nature06547	nature06547	PROPN
cbi-68	118	8	.	.	PUNCT
cbi-68	119	1	pachón	pachón	PROPN
cbi-68	119	2	,	,	PUNCT
cbi-68	119	3	d	d	X
cbi-68	119	4	a	a	DET
cbi-68	119	5	díaz	díaz	NOUN
cbi-68	119	6	and	and	CCONJ
cbi-68	119	7	r	r	NOUN
cbi-68	119	8	j	j	PROPN
cbi-68	119	9	marks	marks	PROPN
cbi-68	119	10	ii	ii	PROPN
cbi-68	119	11	(	(	PUNCT
cbi-68	119	12	2020	2020	NUM
cbi-68	119	13	)	)	PUNCT
cbi-68	119	14	.	.	PUNCT
cbi-68	120	1	“	"	PUNCT
cbi-68	120	2	active	active	ADJ
cbi-68	120	3	information	information	NOUN
cbi-68	120	4	requirements	requirement	NOUN
cbi-68	120	5	for	for	ADP
cbi-68	120	6	fixation	fixation	NOUN
cbi-68	120	7	on	on	ADP
cbi-68	120	8	the	the	DET
cbi-68	120	9	wright	wright	PROPN
cbi-68	120	10	-	-	PUNCT
cbi-68	120	11	fisher	fisher	PROPN
cbi-68	120	12	model	model	NOUN
cbi-68	120	13	of	of	ADP
cbi-68	120	14	population	population	NOUN
cbi-68	120	15	genetics	genetic	NOUN
cbi-68	120	16	”	"	PUNCT
cbi-68	120	17	.	.	PUNCT
cbi-68	121	1	in	in	ADP
cbi-68	121	2	:	:	PUNCT
cbi-68	121	3	bio	bio	NOUN
cbi-68	121	4	-	-	NOUN
cbi-68	121	5	complexity	complexity	NOUN
cbi-68	121	6	4	4	NUM
cbi-68	121	7	,	,	PUNCT
cbi-68	121	8	pp	pp	ADJ
cbi-68	121	9	.	.	PUNCT
cbi-68	122	1	1–6	1–6	X
cbi-68	122	2	.	.	PUNCT
cbi-68	123	1	doi	doi	NOUN
cbi-68	123	2	:	:	PUNCT
cbi-68	123	3	doi:10.5048	doi:10.5048	ADJ
cbi-68	123	4	/	/	SYM
cbi-68	123	5	bio	bio	NOUN
cbi-68	123	6	-	-	PUNCT
cbi-68	123	7	c.2020.4	c.2020.4	PROPN
cbi-68	123	8	.	.	PUNCT
cbi-68	124	1	1supplement	1supplement	NUM
cbi-68	124	2	1	1	NUM
cbi-68	124	3	is	be	AUX
cbi-68	124	4	available	available	ADJ
cbi-68	124	5	online	online	ADV
cbi-68	124	6	at	at	ADP
cbi-68	124	7	https://journals	https://journal	NOUN
cbi-68	124	8	.	.	PUNCT
cbi-68	125	1	blythinstitute.org/ojs/index.php/cbi/article/view/68/66	blythinstitute.org/ojs/index.php/cbi/article/view/68/66	NOUN
cbi-68	125	2	.	.	PUNCT
cbi-68	126	1	https://doi.org/10.1084/jem.20171738	https://doi.org/10.1084/jem.20171738	PROPN
cbi-68	126	2	https://doi.org/10.1084/jem.20171738	https://doi.org/10.1084/jem.20171738	PROPN
cbi-68	126	3	https://doi.org/doi:10.5048/bio-c.2020.2	https://doi.org/doi:10.5048/bio-c.2020.2	PROPN
cbi-68	126	4	https://doi.org/doi:10.5048/bio-c.2020.2	https://doi.org/doi:10.5048/bio-c.2020.2	PROPN
cbi-68	126	5	https://doi.org/10.1109/tsmca.2009.2025027	https://doi.org/10.1109/tsmca.2009.2025027	PROPN
cbi-68	126	6	https://doi.org/10.1038/nature06547	https://doi.org/10.1038/nature06547	VERB
cbi-68	126	7	https://doi.org/doi:10.5048/bio-c.2020.4	https://doi.org/doi:10.5048/bio-c.2020.4	X
cbi-68	126	8	https://journals.blythinstitute.org/ojs/index.php/cbi/article/view/68/66	https://journals.blythinstitute.org/ojs/index.php/cbi/article/view/68/66	PROPN
cbi-68	126	9	https://journals.blythinstitute.org/ojs/index.php/cbi/article/view/68/66	https://journals.blythinstitute.org/ojs/index.php/cbi/article/view/68/66	X
cbi-68	126	10	about	about	ADP
cbi-68	126	11	this	this	DET
cbi-68	126	12	journal	journal	NOUN
cbi-68	126	13	the	the	DET
cbi-68	126	14	purpose	purpose	NOUN
cbi-68	126	15	of	of	ADP
cbi-68	126	16	the	the	DET
cbi-68	126	17	journal	journal	PROPN
cbi-68	126	18	paper	paper	NOUN
cbi-68	126	19	submission	submission	NOUN
cbi-68	126	20	policies	policy	NOUN
cbi-68	126	21	other	other	ADJ
cbi-68	126	22	journal	journal	PROPN
cbi-68	126	23	content	content	NOUN
cbi-68	126	24	from	from	ADP
cbi-68	126	25	the	the	DET
cbi-68	126	26	editors	editor	NOUN
cbi-68	126	27	annie	annie	PROPN
cbi-68	126	28	crawfordannie	crawfordannie	PROPN
cbi-68	126	29	crawfordmetaphor	crawfordmetaphor	NOUN
cbi-68	126	30	and	and	CCONJ
cbi-68	126	31	meaning	meaning	NOUN
cbi-68	126	32	in	in	ADP
cbi-68	126	33	the	the	DET
cbi-68	126	34	teleological	teleological	ADJ
cbi-68	126	35	language	language	NOUN
cbi-68	126	36	of	of	ADP
cbi-68	126	37	biology	biology	NOUN
cbi-68	126	38	introduction	introduction	NOUN
cbi-68	126	39	the	the	DET
cbi-68	126	40	history	history	NOUN
cbi-68	126	41	of	of	ADP
cbi-68	126	42	teleology	teleology	NOUN
cbi-68	126	43	in	in	ADP
cbi-68	126	44	the	the	DET
cbi-68	126	45	biological	biological	ADJ
cbi-68	126	46	sciences	science	NOUN
cbi-68	126	47	teleological	teleological	ADJ
cbi-68	126	48	language	language	NOUN
cbi-68	126	49	is	be	AUX
cbi-68	126	50	essential	essential	ADJ
cbi-68	126	51	to	to	ADP
cbi-68	126	52	biology	biology	NOUN
cbi-68	126	53	if	if	SCONJ
cbi-68	126	54	teleological	teleological	ADJ
cbi-68	126	55	language	language	NOUN
cbi-68	126	56	is	be	AUX
cbi-68	126	57	essential	essential	ADJ
cbi-68	126	58	to	to	ADP
cbi-68	126	59	biology	biology	NOUN
cbi-68	126	60	,	,	PUNCT
cbi-68	126	61	then	then	ADV
cbi-68	126	62	life	life	NOUN
cbi-68	126	63	must	must	AUX
cbi-68	126	64	be	be	AUX
cbi-68	126	65	teleological	teleological	ADJ
cbi-68	126	66	conclusion	conclusion	NOUN
cbi-68	126	67	:	:	PUNCT
cbi-68	126	68	life	life	NOUN
cbi-68	126	69	all	all	DET
cbi-68	126	70	the	the	DET
cbi-68	126	71	way	way	NOUN
cbi-68	126	72	down	down	ADP
cbi-68	126	73	salvador	salvador	PROPN
cbi-68	126	74	cordovasalvador	cordovasalvador	PROPN
cbi-68	126	75	cordovafisher	cordovafisher	PROPN
cbi-68	126	76	's	's	PART
cbi-68	126	77	fundamental	fundamental	ADJ
cbi-68	126	78	theorem	theorem	NOUN
cbi-68	126	79	of	of	ADP
cbi-68	126	80	natural	natural	ADJ
cbi-68	126	81	selection	selection	NOUN
cbi-68	126	82	is	be	AUX
cbi-68	126	83	n't	not	PART
cbi-68	126	84	fundamental	fundamental	ADJ
cbi-68	126	85	after	after	ADP
cbi-68	126	86	all	all	DET
cbi-68	126	87	introduction	introduction	NOUN
cbi-68	126	88	:	:	PUNCT
cbi-68	126	89	the	the	DET
cbi-68	126	90	problem	problem	NOUN
cbi-68	126	91	of	of	ADP
cbi-68	126	92	defining	define	VERB
cbi-68	126	93	fitness	fitness	NOUN
cbi-68	126	94	absolute	absolute	ADJ
cbi-68	126	95	`	`	PUNCT
cbi-68	126	96	`	`	PUNCT
cbi-68	126	97	darwinian	darwinian	ADJ
cbi-68	126	98	''	''	PUNCT
cbi-68	126	99	fitness	fitness	NOUN
cbi-68	126	100	vs.	vs.	ADP
cbi-68	126	101	relative	relative	ADJ
cbi-68	126	102	fitness	fitness	PROPN
cbi-68	126	103	mean	mean	NOUN
cbi-68	126	104	and	and	CCONJ
cbi-68	126	105	variance	variance	NOUN
cbi-68	126	106	of	of	ADP
cbi-68	126	107	relative	relative	ADJ
cbi-68	126	108	fitnesses	fitness	NOUN
cbi-68	126	109	numerical	numerical	ADJ
cbi-68	126	110	examples	example	NOUN
cbi-68	126	111	to	to	PART
cbi-68	126	112	illustrate	illustrate	VERB
cbi-68	126	113	fisher	fisher	PROPN
cbi-68	126	114	's	's	PART
cbi-68	126	115	theorem	theorem	ADJ
cbi-68	126	116	discussion	discussion	NOUN
cbi-68	126	117	conclusion	conclusion	PROPN
cbi-68	126	118	eric	eric	PROPN
cbi-68	126	119	hollowayeric	hollowayeric	PROPN
cbi-68	126	120	hollowaytutorial	hollowaytutorial	PROPN
cbi-68	126	121	:	:	PUNCT
cbi-68	126	122	bioinformatics	bioinformatics	NOUN
cbi-68	126	123	basics	basic	NOUN
cbi-68	126	124	introduction	introduction	VERB
cbi-68	126	125	genetic	genetic	ADJ
cbi-68	126	126	code	code	NOUN
cbi-68	126	127	and	and	CCONJ
cbi-68	126	128	sequence	sequence	NOUN
cbi-68	126	129	translation	translation	NOUN
cbi-68	126	130	sequencing	sequencing	NOUN
cbi-68	126	131	and	and	CCONJ
cbi-68	126	132	assembly	assembly	NOUN
cbi-68	126	133	accessing	access	VERB
cbi-68	126	134	data	datum	NOUN
cbi-68	126	135	finding	find	VERB
cbi-68	126	136	things	thing	NOUN
cbi-68	126	137	with	with	ADP
cbi-68	126	138	blast	blast	NOUN
cbi-68	126	139	summary	summary	NOUN
cbi-68	126	140	letters	letter	NOUN
cbi-68	126	141	and	and	CCONJ
cbi-68	126	142	notes	note	NOUN
cbi-68	126	143	eric	eric	PROPN
cbi-68	126	144	hollowayyou	hollowayyou	PROPN
cbi-68	126	145	can	can	AUX
cbi-68	126	146	not	not	PART
cbi-68	126	147	get	get	VERB
cbi-68	126	148	meaning	meaning	NOUN
cbi-68	126	149	from	from	ADP
cbi-68	126	150	randomness	randomness	NOUN
cbi-68	126	151	jonathan	jonathan	PROPN
cbi-68	126	152	bartlettactive	bartlettactive	PROPN
cbi-68	126	153	information	information	NOUN
cbi-68	126	154	is	be	AUX
cbi-68	126	155	a	a	DET
cbi-68	126	156	specified	specified	ADJ
cbi-68	126	157	complexity	complexity	NOUN
cbi-68	126	158	model	model	NOUN
cbi-68	126	159	eric	eric	PROPN
cbi-68	126	160	hollowayevolution	hollowayevolution	PROPN
cbi-68	126	161	in	in	ADP
cbi-68	126	162	the	the	DET
cbi-68	126	163	valley	valley	NOUN
cbi-68	126	164	of	of	ADP
cbi-68	126	165	illusions	illusion	NOUN
cbi-68	126	166	jonathan	jonathan	PROPN
cbi-68	126	167	bartlettis	bartlettis	PROPN
cbi-68	126	168	active	active	ADJ
cbi-68	126	169	information	information	NOUN
cbi-68	126	170	applicable	applicable	ADJ
cbi-68	126	171	to	to	ADP
cbi-68	126	172	biology	biology	NOUN
cbi-68	126	173	?	?	PUNCT
cbi-68	127	1	eric	eric	PROPN
cbi-68	127	2	hollowayempirical	hollowayempirical	ADJ
cbi-68	127	3	active	active	ADJ
cbi-68	127	4	information	information	NOUN
cbi-68	127	5	news	news	NOUN
