id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cana-5141	Vandana Bhatia	Transformative Approaches to Alzheimer Disease Treatment: Current Progress and Future Direction”	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1137-1154	International Publications	eng	10.52783/cana.v32.5141	https://internationalpubls.com/index.php/cana/article/download/5141/2869	Alzheimer's disease (AD) is a neurological condition that worsens over time and is characterised by tau tangles and amyloid plaques. Current medications mostly address symptoms, despite significant research advancement, leaving a demand for disease-modifying therapy unfulfilled. New treatment approaches target the genetic and molecular causes of AD by focussing on gene editing, specifically the CRISPR-Cas9 system. By specifically editing genes linked to disease, including APP, PSEN1, PSEN2, and APOE4, CRISPR-Cas9 aims to improve neuronal protection and lessen tau and amyloid-beta pathology. Base and prime editing are two recent developments in CRISPR technology that have increased therapeutic potential, decreased off-target effects, and improved editing specificity. In cellular and animal models, preclinical research shows that it is effective in repairing mutations, modifying gene expression, and lowering the synthesis of neurotoxic proteins. Adeno-associated viruses (AAVs) and lipid nanoparticles are two delivery systems that have been created to get across the blood-brain barrier's obstacles. Clinical use is nevertheless hampered by concerns about long-term safety, distribution efficiency, and ethical issues, despite encouraging results. CRISPR-Cas9's combination with immunotherapy and artificial intelligence has created new opportunities for precision medicine by providing specialised methods to address the pathological and genetic characteristics of AD. With its potential to shift AD treatment from symptomatic management to curative approaches, this review focusses on the advancements, difficulties, and prospects of CRISPR-Cas9 in AD therapies. To advance CRISPR-based medicines into clinical practice, ongoing innovation in gene-editing technologies, delivery methods, and ethical frameworks will be essential
oai:ojs2.internationalpubls.com:article/5142	VSSS Prasad Jakkuva, V.V.S. Kesava Rao	Evaluation of Comprehensive Performance Scorecard of State Transport Organizations Using Geometric Similarity-Based MCDM Methods	2025-03-31	Communications on Applied Nonlinear Analysis; Vol. 32 No. 8s (2025); 911 - 932	International Publications	eng	10.52783/cana.v32.5142	https://internationalpubls.com/index.php/cana/article/download/5142/2870	The performance evaluation of State Road Transport Organizations (SRTUs) is essential for ensuring the effective delivery of public transportation services. This study presents a novel multi-criteria decision-making (MCDM) framework employing three geometric similarity-based ranking methods—Ranking by Alternatives Median Similarity (RAMS), Ranking the Alternatives using the Trace to Median Index (RATMI), and Ranking by Alternatives Perimeter Similarity (RAPS). The evaluation is structured around three key dimensions: Physical, Operational, and financial performance. Each dimension comprises a set of relevant indicators to capture the comprehensive functionality of SRTUs. By integrating these advanced ranking techniques, the study facilitates comparison of transport units, enabling more informed managerial decisions. The proposed methodology not only highlights the relative efficiency of different organizations but also provides insights into specific areas of improvement. The results demonstrate the robustness and discriminatory power of the geometric similarity-based methods in prioritizing and benchmarking public transport performance. The results of the geometric similarity based MCDM methods are compared with Multi Attributive Ideal-Real Comparative Analysis (MAIRCA) method
oai:ojs2.internationalpubls.com:article/5143	Jasmine V. H	An Article on Impact of Technology in Construction Dispute Resolution	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1155-1165	International Publications	eng	10.52783/cana.v32.5143	https://internationalpubls.com/index.php/cana/article/download/5143/2871	The construction field is proving to be one of the most dynamic sectors not only on a global scale, but also in India. With a sector subject to extreme technicalities and complexities, it is only rational to infer that disputes arising out of construction activities would also call for distinct expertise and in depth understanding of the issues surrounding construction activities. The construction sector has seen positive growth in the application of Technology. Technological applications have become more independent in the development of problem-solving processes. Despite its incredible contributions, for example the decision-making processes faster, cheaper, and more predictable. Among the biggest beneficiaries of the advancement in technology within the recent past has been the construction industry, which is also complicated by its procedures and disputes. Advancement in technology helps in resolution of the problems of construction through the identification of the digital tools that enhance efficiency, transparency, and fairness. Key technologies such as Building Information Modelling (BIM), blockchain technology, artificial intelligence (AI) and machine learning, drone, project management software, virtual and augmented reality (VR/AR) internet of things (IOT) real-time monitoring and simulation alter traditional approaches to the solution of problems not only does the technology support dispute resolution, but also helps in lowering the level of conflict by providing better management and communication. By using technology in a careful and responsible way, we can help to build trust in digital solutions and make sure that everyone benefits from the amazing potential of this technology. The construction field is riddled with disputes due to its size mainly involving the builders or maybe even between the employees and employer. However, all of this affect the owners, hence there is a need to ensure that the disputes are solved amicably. This abstract examines the Impact of Technology in Construction Dispute Resolution.
oai:ojs2.internationalpubls.com:article/5144	Aijaz Bhat	“Exploring the Role of English Literature in Advancing Sustainable Development Goals”	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1166-1177	International Publications	eng	10.52783/cana.v32.5144	https://internationalpubls.com/index.php/cana/article/download/5144/2872	English literature has long served as a powerful medium for reflecting societal values and inspiring transformative action. This paper explores the role of English literature in advancing the United Nations' Sustainable Development Goals (SDGs) by examining how literary works contribute to raising awareness, shaping critical thought, and driving meaningful discourse on issues like climate action, gender equality, social justice, and quality education. By analysing selected works of English literature through the lens of specific SDGs, this study highlights the profound capacity of literature to foster global citizenship, empathy, and advocacy for sustainable development. The findings underscore the relevance of literature as a cultural and educational tool in promoting the values and principles underpinning the SDGs, ultimately advocating for its greater integration into educational curricula and societal frameworks for sustainable growth
oai:ojs2.internationalpubls.com:article/5145	Jyoti	Influence of Parental Attachment on Emotional Intelligence and Self-Efficacy of Adolescents	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1178-1190	International Publications	eng	10.52783/cana.v32.5145	https://internationalpubls.com/index.php/cana/article/download/5145/2873	Attachment plays a crucial role in the human mind and emotional development. Interactions with the people they are attached are important for shaping society and the self-image of individuals, which are internalized in an internal working model (Bowlby, 1969/1982). Attachment theory is becoming an influential perspective through which people can understand emotional regulation. This research aims to find the relationship between parental attachment, emotional intelligence, and self-efficacy levels of teenagers in senior secondary schools in Punjab.
oai:ojs2.internationalpubls.com:article/5146	Priyanka Devi	Repression and Identity Crisis: As a Thematic Study of the Novel Difficult Daughters by Manju Kapur	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1191-1195	International Publications	eng	10.52783/cana.v32.5146	https://internationalpubls.com/index.php/cana/article/download/5146/2874	Indian patriarchal social system nurtures women in the way that they suffer from distressing thoughts, emotions, desires, and memories. Their social conditioning plays pivotal role to suppress their feelings and choices. These unfulfilled dreams and desire unconsciously stay in their minds. The present research paper is an attempt to study those unconscious repressed emotions those endanger the identity of Indian –middle class women in the patriarchal society. The turmoil between internal feelings and external societal expectation shapes their identity. There is no space for individuality in the life of middle - class women. Their roles as daughters, sisters, wives, and mothers leave no space for their individual self. The patriarchal society not only encroaches the identity of women but restrict their space and agency in the society
oai:ojs2.internationalpubls.com:article/5147	Rineet Kaur	Cinematic Narratives and Legal Realities: Analyzing Transgender Representation in Indian Films	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1196-1208	International Publications	eng	10.52783/cana.v32.5147	https://internationalpubls.com/index.php/cana/article/download/5147/2875	The representation of transgender individuals in Indian cinema has played a pivotal role in shaping public perception and cultural discourse around gender identity. This paper examines the evolution of transgender portrayals in Indian films, analyzing how these narratives reflect societal attitudes and influence legal and policy frameworks concerning transgender rights. By employing a multidisciplinary approach, the research combines perspectives from mass media and law to assess the accuracy and impact of cinematic portrayals. The study critically evaluates the depiction of transgender characters, ranging from stereotypical and marginalized roles to more nuanced and empowering portrayals in recent times. It explores how these representations intersect with legal realities, including the implementation of the Act, 2019, and landmark judicial decisions such as the NALSA judgment of 2014. Additionally, the paper highlights the role of films in fostering societal acceptance and initiating conversations about transgender inclusion and equality. By analyzing selected Indian films and their reception, the research aims to identify gaps between cinematic narratives and the lived experiences of transgender individuals. It also explores the potential of cinema as a medium to advocate for policy changes and challenge entrenched biases. This paper contributes to the discourse on media ethics, gender inclusivity, and the interplay between cultural representation and legal reform in contemporary India.
oai:ojs2.internationalpubls.com:article/5148	Navneet Kaur Jeji	The Role of Visual Arts in Enhancing the Educational Experience	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1209-1217	International Publications	eng	10.52783/cana.v32.5148	https://internationalpubls.com/index.php/cana/article/download/5148/2876	Education, as an evolving process, aims to develop not just cognitive abilities but also emotional and social qualities in students. In this context, visual arts function as a transformative tool for enriching the educational experience, fostering creativity, critical thinking, and emotional intelligence. Traditionally seen as a peripheral component of the curriculum, visual arts are now increasingly recognised for their capacity to enhance learning across several disciplines, addressing distinct learner needs while promoting creative thinking. Eisner (2002) contends that the arts enable students to explore intricate concepts and perplexing realities, cultivating nuanced understandings of the world that go beyond simple memorisation. The visual arts facilitate experiential learning, allowing students to connect academic knowledge with practical application. Hetland et al. (2013) contend that studio-based art education cultivates vital abilities, including observation, tenacity, and critical thinking, pertinent to both academic and professional environments. Through participation in activities such as painting, sculpting, and digital media, students cultivate essential problem-solving and collaboration abilities needed for the 21st-century job (Winner, Goldstein, &amp; Vincent-Lancrin, 2013). Incorporating the arts into the curriculum has demonstrated enhancement in academic achievement in disciplines such as math and science, as the arts promote creative thinking and distinctive problem-solving approaches (Robinson, 2011). Besides cognitive benefits, visual arts are crucial for promoting emotional and social well- being. Wright (2012) underscores that the arts function as a medium for emotional expression, assisting students in navigating complex emotions and fostering empathy. This aligns with the principles of social and emotional learning (SEL), which emphasise self-awareness and interpersonal skills as fundamental educational objectives. Collaborative art projects expose learners to other perspectives and cultural narratives, fostering inclusivity and global citizenship (Deasy, 2002). Malley, Silverstein, and Hedley (2014) contend that arts-based education can eliminate cultural and linguistic barriers, promoting a more inclusive educational atmosphere for students from diverse backgrounds. Besides facilitating personal development, visual arts enhance communal involvement and social progress. Koster (2015) contends that art education fosters a feeling of responsibility and civic involvement in pupils by motivating them to produce works that address social challenges. This enhances their comprehension of the world and fosters active engagement in their communities. Tharp (2003) contends that creativity cultivated via the arts is vital for tackling intricate global issues. Incorporating the psychological, affective, and social aspects of learning, the visual arts have the ability to greatly improve formal education. The arts provide children with well-rounded abilities that go beyond what is taught in the classroom, including the ability to think critically, creatively, empathically, and inclusively. The arts, according to Catterall (2009), are not a frivolous expenditure but rather an essential resource for understanding and educating oneself about the complexities of contemporary life. Based on research and theory, this article will look at how teaching visual arts in the classroom helps students mentally, emotionally, and socially.
oai:ojs2.internationalpubls.com:article/5149	Jasleen Kaur	Gender Representation in the Print Media: A Study of Women’s Issues in Indian Newspapers	2025-04-24	Communications on Applied Nonlinear Analysis; International Conference on Multidisciplinary Approaches for Sustainable Development (ICMASD-2025); 1218-1226	International Publications	eng	10.52783/cana.v32.5149	https://internationalpubls.com/index.php/cana/article/download/5149/2877	This study investigates the representation of women’s issues in Indian print media, emphasizing how gender is portrayed in newspapers. The media plays a pivotal role in shaping public opinion and influencing societal norms, making it essential to examine whether newspapers provide equitable coverage of women’s issues or perpetuate stereotypical gender roles. Through a content analysis of selected national and regional newspapers, this research explores the framing of key issues such as gender inequality, empowerment, and social justice. It delves into the use of language, imagery, and narratives, identifying whether they challenge or reinforce existing stereotypes. Furthermore, the study evaluates the diversity and inclusivity of women’s voices, considering factors such as regional, socio-economic, and cultural representation. By analyzing patterns in news reporting, feature articles, and editorials, this research uncovers biases or progressive trends in the portrayal of women. The findings aim to contribute to the ongoing discourse on media responsibility in fostering gender equality, offering insights into the need for more inclusive and balanced reporting. Ultimately, this study seeks to highlight the critical role of print media in shaping perceptions of women and advancing societal change, while proposing recommendations for gender-sensitive journalism.
oai:ojs2.internationalpubls.com:article/5150	Vishakha Kapila	Young Adult Literature as a Tool for Empathy: Exploring Social Cohesion in Dasgupta’s and Perkins’ Narratives (SDG 16 - Peace, Justice, and Strong Institutions)"	2025	18	.pdf	application/pdf	7962	386	45	[9] D. Gupta et al., ‘CRISPR-Cas9 system: A new-fangled dawn in gene editing’, Life Sci, vol. 232, p. 116636, Sep. 2019, doi: 10.1016/j.lfs.2019.116636. [20] N. R. Barthélemy et al., ‘A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease’, Nat Med, vol. 26, no. 3, pp.	cache/cana-5141.pdf	txt/cana-5141.txt
