id	sid	tid	token	lemma	pos
cana-431	1	1	communications	communication	NOUN
cana-431	1	2	on	on	ADP
cana-431	1	3	applied	apply	VERB
cana-431	1	4	nonlinear	nonlinear	ADJ
cana-431	1	5	analysis	analysis	NOUN
cana-431	1	6	issn	issn	NOUN
cana-431	1	7	:	:	PUNCT
cana-431	1	8	1074	1074	NUM
cana-431	1	9	-	-	PUNCT
cana-431	1	10	133x	133x	NUM
cana-431	1	11	vol	vol	NOUN
cana-431	1	12	31	31	NUM
cana-431	1	13	no	no	NOUN
cana-431	1	14	.	.	NOUN
cana-431	1	15	1	1	NUM
cana-431	1	16	(	(	PUNCT
cana-431	1	17	2024	2024	NUM
cana-431	1	18	)	)	PUNCT
cana-431	1	19	287	287	NUM
cana-431	1	20	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	1	21	optimization	optimization	NOUN
cana-431	1	22	for	for	ADP
cana-431	1	23	parameter	parameter	NOUN
cana-431	1	24	estimation	estimation	NOUN
cana-431	1	25	in	in	ADP
cana-431	1	26	mathematical	mathematical	ADJ
cana-431	1	27	model	model	NOUN
cana-431	1	28	to	to	PART
cana-431	1	29	predict	predict	VERB
cana-431	1	30	the	the	DET
cana-431	1	31	behaviour	behaviour	NOUN
cana-431	1	32	of	of	ADP
cana-431	1	33	immune	immune	ADJ
cana-431	1	34	system	system	NOUN
cana-431	1	35	mrs	mrs	PROPN
cana-431	1	36	.	.	PROPN
cana-431	1	37	shital	shital	PROPN
cana-431	1	38	yadav1	yadav1	PROPN
cana-431	1	39	,	,	PUNCT
cana-431	1	40	dr	dr	PROPN
cana-431	1	41	.	.	PROPN
cana-431	1	42	anisa	anisa	PROPN
cana-431	1	43	ahmad2	ahmad2	PROPN
cana-431	1	44	,	,	PUNCT
cana-431	1	45	dr	dr	PROPN
cana-431	1	46	.	.	PROPN
cana-431	1	47	nalini	nalini	PROPN
cana-431	1	48	vaidya3	vaidya3	PROPN
cana-431	2	1	1research	1research	NUM
cana-431	2	2	scholar	scholar	NOUN
cana-431	2	3	of	of	ADP
cana-431	2	4	mathematics	mathematics	PROPN
cana-431	2	5	,	,	PUNCT
cana-431	2	6	g.h	g.h	PROPN
cana-431	2	7	.	.	PROPN
cana-431	2	8	raisoni	raisoni	PROPN
cana-431	2	9	university	university	PROPN
cana-431	2	10	,	,	PUNCT
cana-431	2	11	amravati	amravati	PROPN
cana-431	2	12	2g.h	2g.h	NUM
cana-431	2	13	.	.	PUNCT
cana-431	3	1	raisoni	raisoni	PROPN
cana-431	3	2	university	university	PROPN
cana-431	3	3	,	,	PUNCT
cana-431	3	4	amravati	amravati	PROPN
cana-431	3	5	.	.	PROPN
cana-431	4	1	3g.h	3g.h	NUM
cana-431	4	2	.	.	PUNCT
cana-431	4	3	raisoni	raisoni	PROPN
cana-431	4	4	college	college	PROPN
cana-431	4	5	of	of	ADP
cana-431	4	6	engineering	engineering	PROPN
cana-431	4	7	,	,	PUNCT
cana-431	4	8	nagpur	nagpur	NOUN
cana-431	4	9	1shital.yadav@raisoni.net	1shital.yadav@raisoni.net	NUM
cana-431	4	10	2anisa.ahmad@raisoni.net	2anisa.ahmad@raisoni.net	NUM
cana-431	4	11	,	,	PUNCT
cana-431	4	12	3nalini.vaidya@raisoni.net	3nalini.vaidya@raisoni.net	NUM
cana-431	4	13	article	article	NOUN
cana-431	4	14	history	history	NOUN
cana-431	4	15	:	:	PUNCT
cana-431	4	16	received	receive	VERB
cana-431	4	17	:	:	PUNCT
cana-431	4	18	30	30	NUM
cana-431	4	19	-	-	SYM
cana-431	4	20	10	10	NUM
cana-431	4	21	-	-	PUNCT
cana-431	4	22	2023	2023	NUM
cana-431	4	23	revised	revise	VERB
cana-431	4	24	:	:	PUNCT
cana-431	4	25	18	18	NUM
cana-431	4	26	-	-	SYM
cana-431	4	27	12	12	NUM
cana-431	4	28	-	-	PUNCT
cana-431	4	29	2023	2023	NUM
cana-431	4	30	accepted	accept	VERB
cana-431	4	31	:	:	PUNCT
cana-431	4	32	24	24	NUM
cana-431	4	33	-	-	SYM
cana-431	4	34	12	12	NUM
cana-431	4	35	-	-	PUNCT
cana-431	4	36	2023	2023	NUM
cana-431	4	37	abstract	abstract	NOUN
cana-431	4	38	:	:	PUNCT
cana-431	4	39	this	this	DET
cana-431	4	40	paper	paper	NOUN
cana-431	4	41	surveys	survey	NOUN
cana-431	4	42	and	and	CCONJ
cana-431	4	43	compares	compare	VERB
cana-431	4	44	various	various	ADJ
cana-431	4	45	optimization	optimization	NOUN
cana-431	4	46	functions	function	NOUN
cana-431	4	47	related	relate	VERB
cana-431	4	48	to	to	ADP
cana-431	4	49	diabetes	diabetes	NOUN
cana-431	4	50	to	to	PART
cana-431	4	51	study	study	VERB
cana-431	4	52	the	the	DET
cana-431	4	53	various	various	ADJ
cana-431	4	54	parameter	parameter	NOUN
cana-431	4	55	affecting	affect	VERB
cana-431	4	56	on	on	ADP
cana-431	4	57	diabetes	diabetes	NOUN
cana-431	4	58	.	.	PUNCT
cana-431	5	1	the	the	DET
cana-431	5	2	most	most	ADV
cana-431	5	3	important	important	ADJ
cana-431	5	4	stage	stage	NOUN
cana-431	5	5	in	in	ADP
cana-431	5	6	improving	improve	VERB
cana-431	5	7	the	the	DET
cana-431	5	8	precision	precision	NOUN
cana-431	5	9	and	and	CCONJ
cana-431	5	10	predictive	predictive	ADJ
cana-431	5	11	ability	ability	NOUN
cana-431	5	12	of	of	ADP
cana-431	5	13	mathematical	mathematical	ADJ
cana-431	5	14	models	model	NOUN
cana-431	5	15	is	be	AUX
cana-431	5	16	parameter	parameter	NOUN
cana-431	5	17	estimation	estimation	NOUN
cana-431	5	18	.	.	PUNCT
cana-431	6	1	mathematical	mathematical	ADJ
cana-431	6	2	models	model	NOUN
cana-431	6	3	for	for	ADP
cana-431	6	4	immunity	immunity	NOUN
cana-431	6	5	are	be	AUX
cana-431	6	6	used	use	VERB
cana-431	6	7	to	to	PART
cana-431	6	8	describe	describe	VERB
cana-431	6	9	and	and	CCONJ
cana-431	6	10	predict	predict	VERB
cana-431	6	11	the	the	DET
cana-431	6	12	behaviour	behaviour	NOUN
cana-431	6	13	of	of	ADP
cana-431	6	14	the	the	DET
cana-431	6	15	immune	immune	ADJ
cana-431	6	16	system	system	NOUN
cana-431	6	17	in	in	ADP
cana-431	6	18	response	response	NOUN
cana-431	6	19	to	to	ADP
cana-431	6	20	infections	infection	NOUN
cana-431	6	21	,	,	PUNCT
cana-431	6	22	vaccinations	vaccination	NOUN
cana-431	6	23	,	,	PUNCT
cana-431	6	24	and	and	CCONJ
cana-431	6	25	various	various	ADJ
cana-431	6	26	other	other	ADJ
cana-431	6	27	immunological	immunological	ADJ
cana-431	6	28	processes	process	NOUN
cana-431	6	29	.	.	PUNCT
cana-431	7	1	these	these	DET
cana-431	7	2	models	model	NOUN
cana-431	7	3	are	be	AUX
cana-431	7	4	quite	quite	ADV
cana-431	7	5	complex	complex	ADJ
cana-431	7	6	,	,	PUNCT
cana-431	7	7	involved	involve	VERB
cana-431	7	8	differential	differential	ADJ
cana-431	7	9	equations	equation	NOUN
cana-431	7	10	and	and	CCONJ
cana-431	7	11	various	various	ADJ
cana-431	7	12	parameters	parameter	NOUN
cana-431	7	13	.	.	PUNCT
cana-431	8	1	ongoing	ongoing	ADJ
cana-431	8	2	research	research	NOUN
cana-431	8	3	aims	aim	VERB
cana-431	8	4	to	to	PART
cana-431	8	5	better	well	ADV
cana-431	8	6	understand	understand	VERB
cana-431	8	7	these	these	DET
cana-431	8	8	immune	immune	NOUN
cana-431	8	9	-	-	PUNCT
cana-431	8	10	related	relate	VERB
cana-431	8	11	conditions	condition	NOUN
cana-431	8	12	and	and	CCONJ
cana-431	8	13	develop	develop	VERB
cana-431	8	14	targeted	target	VERB
cana-431	8	15	treatments	treatment	NOUN
cana-431	8	16	to	to	PART
cana-431	8	17	modulate	modulate	VERB
cana-431	8	18	immune	immune	ADJ
cana-431	8	19	responses	response	NOUN
cana-431	8	20	appropriately	appropriately	ADV
cana-431	8	21	related	relate	VERB
cana-431	8	22	to	to	ADP
cana-431	8	23	diabetes	diabetes	NOUN
cana-431	8	24	disease	disease	NOUN
cana-431	8	25	.	.	PUNCT
cana-431	9	1	keywords	keyword	NOUN
cana-431	9	2	:	:	PUNCT
cana-431	9	3	immunotherapy	immunotherapy	NOUN
cana-431	9	4	,	,	PUNCT
cana-431	9	5	decision	decision	NOUN
cana-431	9	6	variable	variable	NOUN
cana-431	9	7	,	,	PUNCT
cana-431	9	8	multistage	multistage	NOUN
cana-431	9	9	model	model	NOUN
cana-431	9	10	,	,	PUNCT
cana-431	9	11	auto	auto	NOUN
cana-431	9	12	immune	immune	NOUN
cana-431	9	13	,	,	PUNCT
cana-431	9	14	diabetes	diabetes	NOUN
cana-431	9	15	mellitus	mellitus	NOUN
cana-431	9	16	.	.	PUNCT
cana-431	10	1	introduction	introduction	NOUN
cana-431	10	2	:	:	PUNCT
cana-431	10	3	1.1background	1.1background	NUM
cana-431	10	4	an	an	DET
cana-431	10	5	immune	immune	ADJ
cana-431	10	6	system	system	NOUN
cana-431	10	7	always	always	ADV
cana-431	10	8	protects	protect	VERB
cana-431	10	9	the	the	DET
cana-431	10	10	human	human	ADJ
cana-431	10	11	body	body	NOUN
cana-431	10	12	from	from	ADP
cana-431	10	13	infections	infection	NOUN
cana-431	10	14	,	,	PUNCT
cana-431	10	15	diseases	disease	NOUN
cana-431	10	16	,	,	PUNCT
cana-431	10	17	and	and	CCONJ
cana-431	10	18	other	other	ADJ
cana-431	10	19	threats	threat	NOUN
cana-431	10	20	.	.	PUNCT
cana-431	11	1	understanding	understand	VERB
cana-431	11	2	the	the	DET
cana-431	11	3	compatible	compatible	ADJ
cana-431	11	4	dynamics	dynamic	NOUN
cana-431	11	5	of	of	ADP
cana-431	11	6	immune	immune	ADJ
cana-431	11	7	responses	response	NOUN
cana-431	11	8	is	be	AUX
cana-431	11	9	essential	essential	ADJ
cana-431	11	10	for	for	ADP
cana-431	11	11	developing	develop	VERB
cana-431	11	12	effective	effective	ADJ
cana-431	11	13	treatments	treatment	NOUN
cana-431	11	14	,	,	PUNCT
cana-431	11	15	vaccines	vaccine	NOUN
cana-431	11	16	,	,	PUNCT
cana-431	11	17	and	and	CCONJ
cana-431	11	18	therapies	therapy	NOUN
cana-431	11	19	.	.	PUNCT
cana-431	12	1	human	human	ADJ
cana-431	12	2	health	health	NOUN
cana-431	12	3	is	be	AUX
cana-431	12	4	totally	totally	ADV
cana-431	12	5	depending	depend	VERB
cana-431	12	6	on	on	ADP
cana-431	12	7	the	the	DET
cana-431	12	8	immune	immune	ADJ
cana-431	12	9	system	system	NOUN
cana-431	12	10	if	if	SCONJ
cana-431	12	11	it	it	PRON
cana-431	12	12	is	be	AUX
cana-431	12	13	strong	strong	ADJ
cana-431	12	14	then	then	ADV
cana-431	12	15	human	human	ADJ
cana-431	12	16	health	health	NOUN
cana-431	12	17	is	be	AUX
cana-431	12	18	strong	strong	ADJ
cana-431	12	19	and	and	CCONJ
cana-431	12	20	if	if	SCONJ
cana-431	12	21	one	one	NUM
cana-431	12	22	of	of	ADP
cana-431	12	23	the	the	DET
cana-431	12	24	parameters	parameter	NOUN
cana-431	12	25	related	relate	VERB
cana-431	12	26	to	to	ADP
cana-431	12	27	immune	immune	ADJ
cana-431	12	28	system	system	NOUN
cana-431	12	29	is	be	AUX
cana-431	12	30	weaken	weaken	VERB
cana-431	12	31	then	then	ADV
cana-431	12	32	its	its	PRON
cana-431	12	33	directly	directly	ADV
cana-431	12	34	affect	affect	VERB
cana-431	12	35	the	the	DET
cana-431	12	36	human	human	ADJ
cana-431	12	37	health	health	NOUN
cana-431	12	38	.	.	PUNCT
cana-431	13	1	mathematical	mathematical	ADJ
cana-431	13	2	modelling	modelling	NOUN
cana-431	13	3	offers	offer	VERB
cana-431	13	4	a	a	DET
cana-431	13	5	powerful	powerful	ADJ
cana-431	13	6	approach	approach	NOUN
cana-431	13	7	to	to	PART
cana-431	13	8	study	study	VERB
cana-431	13	9	the	the	DET
cana-431	13	10	complexities	complexity	NOUN
cana-431	13	11	of	of	ADP
cana-431	13	12	the	the	DET
cana-431	13	13	immune	immune	ADJ
cana-431	13	14	system	system	NOUN
cana-431	13	15	,	,	PUNCT
cana-431	13	16	providing	provide	VERB
cana-431	13	17	insights	insight	NOUN
cana-431	13	18	that	that	PRON
cana-431	13	19	can	can	AUX
cana-431	13	20	guide	guide	VERB
cana-431	13	21	experimental	experimental	ADJ
cana-431	13	22	research	research	NOUN
cana-431	13	23	and	and	CCONJ
cana-431	13	24	clinical	clinical	ADJ
cana-431	13	25	interventions	intervention	NOUN
cana-431	13	26	.	.	PUNCT
cana-431	14	1	the	the	DET
cana-431	14	2	relationship	relationship	NOUN
cana-431	14	3	between	between	ADP
cana-431	14	4	diabetes	diabetes	NOUN
cana-431	14	5	and	and	CCONJ
cana-431	14	6	the	the	DET
cana-431	14	7	immune	immune	ADJ
cana-431	14	8	system	system	NOUN
cana-431	14	9	is	be	AUX
cana-431	14	10	complex	complex	ADJ
cana-431	14	11	,	,	PUNCT
cana-431	14	12	and	and	CCONJ
cana-431	14	13	it	it	PRON
cana-431	14	14	varies	vary	VERB
cana-431	14	15	depending	depend	VERB
cana-431	14	16	on	on	ADP
cana-431	14	17	the	the	DET
cana-431	14	18	type	type	NOUN
cana-431	14	19	of	of	ADP
cana-431	14	20	diabetes	diabetes	NOUN
cana-431	14	21	[	[	X
cana-431	14	22	1	1	NUM
cana-431	14	23	]	]	PUNCT
cana-431	14	24	.	.	PUNCT
cana-431	15	1	diabetes	diabetes	NOUN
cana-431	15	2	which	which	PRON
cana-431	15	3	is	be	AUX
cana-431	15	4	also	also	ADV
cana-431	15	5	known	know	VERB
cana-431	15	6	by	by	ADP
cana-431	15	7	the	the	DET
cana-431	15	8	name	name	NOUN
cana-431	15	9	diabetes	diabetes	NOUN
cana-431	15	10	mellitus	mellitus	NOUN
cana-431	15	11	.	.	PUNCT
cana-431	16	1	if	if	SCONJ
cana-431	16	2	one	one	NUM
cana-431	16	3	of	of	ADP
cana-431	16	4	the	the	DET
cana-431	16	5	persons	person	NOUN
cana-431	16	6	suffered	suffer	VERB
cana-431	16	7	from	from	ADP
cana-431	16	8	the	the	DET
cana-431	16	9	diabetes	diabetes	NOUN
cana-431	16	10	then	then	ADV
cana-431	16	11	it	it	PRON
cana-431	16	12	ca	can	AUX
cana-431	16	13	n’t	not	PART
cana-431	16	14	end	end	VERB
cana-431	16	15	by	by	ADP
cana-431	16	16	just	just	ADV
cana-431	16	17	taking	take	VERB
cana-431	16	18	a	a	DET
cana-431	16	19	medicine	medicine	NOUN
cana-431	16	20	or	or	CCONJ
cana-431	16	21	stop	stop	VERB
cana-431	16	22	within	within	ADP
cana-431	16	23	5	5	NUM
cana-431	16	24	to	to	PART
cana-431	16	25	6	6	NUM
cana-431	16	26	days	day	NOUN
cana-431	16	27	,	,	PUNCT
cana-431	16	28	with	with	ADP
cana-431	16	29	proper	proper	ADJ
cana-431	16	30	medicine	medicine	NOUN
cana-431	16	31	,	,	PUNCT
cana-431	16	32	diet	diet	NOUN
cana-431	16	33	,	,	PUNCT
cana-431	16	34	exercise	exercise	VERB
cana-431	16	35	it	it	PRON
cana-431	16	36	can	can	AUX
cana-431	16	37	just	just	ADV
cana-431	16	38	control	control	VERB
cana-431	16	39	.	.	PUNCT
cana-431	17	1	so	so	ADV
cana-431	17	2	,	,	PUNCT
cana-431	17	3	diabetes	diabetes	NOUN
cana-431	17	4	is	be	AUX
cana-431	17	5	also	also	ADV
cana-431	17	6	known	know	VERB
cana-431	17	7	to	to	PART
cana-431	17	8	be	be	AUX
cana-431	17	9	a	a	DET
cana-431	17	10	one	one	NUM
cana-431	17	11	of	of	ADP
cana-431	17	12	the	the	DET
cana-431	17	13	most	most	ADJ
cana-431	17	14	killer	killer	NOUN
cana-431	17	15	diseases	disease	NOUN
cana-431	17	16	in	in	ADP
cana-431	17	17	the	the	DET
cana-431	17	18	world	world	NOUN
cana-431	17	19	.	.	PUNCT
cana-431	18	1	diabetes	diabetes	NOUN
cana-431	18	2	occurs	occur	VERB
cana-431	18	3	in	in	ADP
cana-431	18	4	human	human	ADJ
cana-431	18	5	being	being	NOUN
cana-431	18	6	when	when	SCONJ
cana-431	18	7	pancreas	pancreas	NOUN
cana-431	18	8	is	be	AUX
cana-431	18	9	unable	unable	ADJ
cana-431	18	10	to	to	PART
cana-431	18	11	secrete	secrete	VERB
cana-431	18	12	the	the	DET
cana-431	18	13	proper	proper	ADJ
cana-431	18	14	insulin	insulin	NOUN
cana-431	18	15	so	so	SCONJ
cana-431	18	16	that	that	SCONJ
cana-431	18	17	the	the	DET
cana-431	18	18	glucose	glucose	NOUN
cana-431	18	19	level	level	NOUN
cana-431	18	20	in	in	ADP
cana-431	18	21	the	the	DET
cana-431	18	22	body	body	NOUN
cana-431	18	23	can	can	AUX
cana-431	18	24	not	not	PART
cana-431	18	25	be	be	AUX
cana-431	18	26	controlled	control	VERB
cana-431	18	27	.	.	PUNCT
cana-431	19	1	insulin	insulin	NOUN
cana-431	19	2	is	be	AUX
cana-431	19	3	one	one	NUM
cana-431	19	4	of	of	ADP
cana-431	19	5	the	the	DET
cana-431	19	6	hormones	hormone	NOUN
cana-431	19	7	produce	produce	VERB
cana-431	19	8	by	by	ADP
cana-431	19	9	the	the	DET
cana-431	19	10	pancreas	pancrea	NOUN
cana-431	19	11	to	to	PART
cana-431	19	12	regulates	regulate	VERB
cana-431	19	13	the	the	DET
cana-431	19	14	blood	blood	NOUN
cana-431	19	15	sugar	sugar	NOUN
cana-431	19	16	[	[	X
cana-431	19	17	2	2	NUM
cana-431	19	18	]	]	PUNCT
cana-431	19	19	.	.	PUNCT
cana-431	20	1	again	again	ADV
cana-431	20	2	,	,	PUNCT
cana-431	20	3	person	person	NOUN
cana-431	20	4	suffered	suffer	VERB
cana-431	20	5	from	from	ADP
cana-431	20	6	the	the	DET
cana-431	20	7	diabetes	diabetes	NOUN
cana-431	20	8	having	have	VERB
cana-431	20	9	the	the	DET
cana-431	20	10	different	different	ADJ
cana-431	20	11	kind	kind	NOUN
cana-431	20	12	of	of	ADP
cana-431	20	13	sugar	sugar	NOUN
cana-431	20	14	level	level	NOUN
cana-431	20	15	.	.	PUNCT
cana-431	21	1	most	most	ADJ
cana-431	21	2	of	of	ADP
cana-431	21	3	the	the	DET
cana-431	21	4	higher	high	ADJ
cana-431	21	5	risk	risk	NOUN
cana-431	21	6	diseases	disease	NOUN
cana-431	21	7	like	like	ADP
cana-431	21	8	heart	heart	NOUN
cana-431	21	9	stroke	stroke	NOUN
cana-431	21	10	,	,	PUNCT
cana-431	21	11	brain	brain	NOUN
cana-431	21	12	disorder	disorder	NOUN
cana-431	21	13	,	,	PUNCT
cana-431	21	14	effects	effect	NOUN
cana-431	21	15	on	on	ADP
cana-431	21	16	eye	eye	NOUN
cana-431	21	17	sight	sight	NOUN
cana-431	21	18	,	,	PUNCT
cana-431	21	19	improper	improper	ADJ
cana-431	21	20	kidney	kidney	NOUN
cana-431	21	21	function	function	NOUN
cana-431	21	22	,	,	PUNCT
cana-431	21	23	effects	effect	NOUN
cana-431	21	24	on	on	ADP
cana-431	21	25	the	the	DET
cana-431	21	26	nervous	nervous	ADJ
cana-431	21	27	system	system	NOUN
cana-431	21	28	etc	etc	X
cana-431	21	29	.	.	X
cana-431	21	30	are	be	AUX
cana-431	21	31	occurred	occur	VERB
cana-431	21	32	in	in	ADP
cana-431	21	33	human	human	ADJ
cana-431	21	34	being	be	AUX
cana-431	21	35	only	only	ADV
cana-431	21	36	due	due	ADJ
cana-431	21	37	to	to	ADP
cana-431	21	38	the	the	DET
cana-431	21	39	diabetes	diabetes	NOUN
cana-431	21	40	.	.	PUNCT
cana-431	22	1	communications	communication	NOUN
cana-431	22	2	on	on	ADP
cana-431	22	3	applied	apply	VERB
cana-431	22	4	nonlinear	nonlinear	ADJ
cana-431	22	5	analysis	analysis	NOUN
cana-431	22	6	issn	issn	NOUN
cana-431	22	7	:	:	PUNCT
cana-431	22	8	1074	1074	NUM
cana-431	22	9	-	-	PUNCT
cana-431	22	10	133x	133x	NUM
cana-431	22	11	vol	vol	NOUN
cana-431	22	12	31	31	NUM
cana-431	22	13	no	no	NOUN
cana-431	22	14	.	.	NOUN
cana-431	22	15	1	1	NUM
cana-431	22	16	(	(	PUNCT
cana-431	22	17	2024	2024	NUM
cana-431	22	18	)	)	PUNCT
cana-431	22	19	288	288	NUM
cana-431	22	20	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	22	21	diabetes	diabetes	NOUN
cana-431	22	22	is	be	AUX
cana-431	22	23	of	of	ADP
cana-431	22	24	two	two	NUM
cana-431	22	25	types	type	NOUN
cana-431	22	26	mainly	mainly	ADV
cana-431	22	27	:	:	PUNCT
cana-431	22	28	type-1	type-1	NUM
cana-431	22	29	or	or	CCONJ
cana-431	22	30	t1	t1	NUM
cana-431	22	31	diabetes	diabetes	NOUN
cana-431	22	32	and	and	CCONJ
cana-431	22	33	type-2	type-2	NUM
cana-431	22	34	or	or	CCONJ
cana-431	22	35	t2	t2	NOUN
cana-431	22	36	diabetes	diabetes	NOUN
cana-431	22	37	.	.	PUNCT
cana-431	23	1	type-1	type-1	NUM
cana-431	23	2	diabetes	diabetes	NOUN
cana-431	23	3	is	be	AUX
cana-431	23	4	characterized	characterize	VERB
cana-431	23	5	by	by	ADP
cana-431	23	6	an	an	DET
cana-431	23	7	autoimmune	autoimmune	ADJ
cana-431	23	8	response	response	NOUN
cana-431	23	9	.	.	PUNCT
cana-431	24	1	beta	beta	ADJ
cana-431	24	2	cells	cell	NOUN
cana-431	24	3	in	in	ADP
cana-431	24	4	the	the	DET
cana-431	24	5	pancreas	pancreas	NOUN
cana-431	24	6	responsible	responsible	ADJ
cana-431	24	7	for	for	ADP
cana-431	24	8	producing	produce	VERB
cana-431	24	9	the	the	DET
cana-431	24	10	insulin	insulin	NOUN
cana-431	24	11	which	which	PRON
cana-431	24	12	is	be	AUX
cana-431	24	13	required	require	VERB
cana-431	24	14	to	to	PART
cana-431	24	15	control	control	VERB
cana-431	24	16	the	the	DET
cana-431	24	17	glucose	glucose	NOUN
cana-431	24	18	in	in	ADP
cana-431	24	19	the	the	DET
cana-431	24	20	blood	blood	NOUN
cana-431	24	21	.	.	PUNCT
cana-431	25	1	in	in	ADP
cana-431	25	2	auto	auto	NOUN
cana-431	25	3	immune	immune	ADJ
cana-431	25	4	response	response	NOUN
cana-431	25	5	insulinproducing	insulinproduce	VERB
cana-431	25	6	beta	beta	ADJ
cana-431	25	7	cells	cell	NOUN
cana-431	25	8	in	in	ADP
cana-431	25	9	the	the	DET
cana-431	25	10	pancreas	pancreas	NOUN
cana-431	25	11	destroys	destroy	VERB
cana-431	25	12	and	and	CCONJ
cana-431	25	13	attacks	attack	NOUN
cana-431	25	14	by	by	ADP
cana-431	25	15	the	the	DET
cana-431	25	16	immune	immune	ADJ
cana-431	25	17	system	system	NOUN
cana-431	25	18	mistakenly	mistakenly	ADV
cana-431	25	19	.	.	PUNCT
cana-431	26	1	2	2	NUM
cana-431	26	2	types	type	NOUN
cana-431	26	3	of	of	ADP
cana-431	26	4	t	t	NOUN
cana-431	26	5	cell	cell	NOUN
cana-431	26	6	mainly	mainly	ADV
cana-431	26	7	regulatory	regulatory	ADJ
cana-431	26	8	t	t	NOUN
cana-431	26	9	cells	cell	NOUN
cana-431	26	10	and	and	CCONJ
cana-431	26	11	autoreactive	autoreactive	ADJ
cana-431	26	12	t	t	NOUN
cana-431	26	13	cells	cell	NOUN
cana-431	26	14	involved	involve	VERB
cana-431	26	15	in	in	ADP
cana-431	26	16	the	the	DET
cana-431	26	17	diabetes	diabetes	NOUN
cana-431	26	18	[	[	X
cana-431	26	19	3,6	3,6	NUM
cana-431	26	20	]	]	PUNCT
cana-431	26	21	.	.	PUNCT
cana-431	27	1	autoreactive	autoreactive	PROPN
cana-431	27	2	t	t	PROPN
cana-431	27	3	cell	cell	NOUN
cana-431	27	4	kills	kill	VERB
cana-431	27	5	the	the	DET
cana-431	27	6	cells	cell	NOUN
cana-431	27	7	which	which	PRON
cana-431	27	8	is	be	AUX
cana-431	27	9	responsible	responsible	ADJ
cana-431	27	10	for	for	ADP
cana-431	27	11	creating	create	VERB
cana-431	27	12	the	the	DET
cana-431	27	13	insulin	insulin	NOUN
cana-431	27	14	to	to	PART
cana-431	27	15	control	control	VERB
cana-431	27	16	the	the	DET
cana-431	27	17	glucose	glucose	NOUN
cana-431	27	18	level	level	NOUN
cana-431	27	19	in	in	ADP
cana-431	27	20	human	human	ADJ
cana-431	27	21	body	body	NOUN
cana-431	27	22	while	while	SCONJ
cana-431	27	23	regulatory	regulatory	ADJ
cana-431	27	24	cells	cell	NOUN
cana-431	27	25	control	control	VERB
cana-431	27	26	the	the	DET
cana-431	27	27	autoreactive	autoreactive	ADJ
cana-431	27	28	t	t	NOUN
cana-431	27	29	cells	cell	NOUN
cana-431	27	30	.	.	PUNCT
cana-431	28	1	hereditary	hereditary	ADJ
cana-431	28	2	and	and	CCONJ
cana-431	28	3	environmental	environmental	ADJ
cana-431	28	4	factors	factor	NOUN
cana-431	28	5	might	might	AUX
cana-431	28	6	cause	cause	VERB
cana-431	28	7	this	this	DET
cana-431	28	8	autoimmune	autoimmune	ADJ
cana-431	28	9	reaction	reaction	NOUN
cana-431	28	10	.	.	PUNCT
cana-431	29	1	the	the	DET
cana-431	29	2	immune	immune	ADJ
cana-431	29	3	system	system	NOUN
cana-431	29	4	's	's	PART
cana-431	29	5	t	t	NOUN
cana-431	29	6	cells	cell	NOUN
cana-431	29	7	and	and	CCONJ
cana-431	29	8	antibodies	antibody	NOUN
cana-431	29	9	are	be	AUX
cana-431	29	10	responsible	responsible	ADJ
cana-431	29	11	in	in	ADP
cana-431	29	12	the	the	DET
cana-431	29	13	breakdown	breakdown	NOUN
cana-431	29	14	of	of	ADP
cana-431	29	15	beta	beta	ADJ
cana-431	29	16	cells	cell	NOUN
cana-431	29	17	in	in	ADP
cana-431	29	18	individuals	individual	NOUN
cana-431	29	19	who	who	PRON
cana-431	29	20	have	have	AUX
cana-431	29	21	type	type	NOUN
cana-431	29	22	1	1	NUM
cana-431	29	23	diabetes	diabetes	NOUN
cana-431	29	24	.	.	PUNCT
cana-431	30	1	insulin	insulin	NOUN
cana-431	30	2	,	,	PUNCT
cana-431	30	3	a	a	DET
cana-431	30	4	hormone	hormone	NOUN
cana-431	30	5	required	require	VERB
cana-431	30	6	for	for	ADP
cana-431	30	7	controlling	control	VERB
cana-431	30	8	blood	blood	NOUN
cana-431	30	9	sugar	sugar	NOUN
cana-431	30	10	(	(	PUNCT
cana-431	30	11	glucose	glucose	NOUN
cana-431	30	12	)	)	PUNCT
cana-431	30	13	levels	level	NOUN
cana-431	30	14	,	,	PUNCT
cana-431	30	15	is	be	AUX
cana-431	30	16	thus	thus	ADV
cana-431	30	17	lacked	lack	VERB
cana-431	30	18	[	[	PUNCT
cana-431	30	19	4	4	NUM
cana-431	30	20	-	-	SYM
cana-431	30	21	5	5	NUM
cana-431	30	22	]	]	PUNCT
cana-431	30	23	.	.	PUNCT
cana-431	31	1	type-2	type-2	NUM
cana-431	31	2	diabetes	diabetes	NOUN
cana-431	31	3	is	be	AUX
cana-431	31	4	not	not	PART
cana-431	31	5	be	be	AUX
cana-431	31	6	considered	consider	VERB
cana-431	31	7	as	as	ADP
cana-431	31	8	an	an	DET
cana-431	31	9	autoimmune	autoimmune	ADJ
cana-431	31	10	disorder	disorder	NOUN
cana-431	31	11	,	,	PUNCT
cana-431	31	12	as	as	SCONJ
cana-431	31	13	research	research	NOUN
cana-431	31	14	suggests	suggest	VERB
cana-431	31	15	in	in	ADP
cana-431	31	16	the	the	DET
cana-431	31	17	development	development	NOUN
cana-431	31	18	of	of	ADP
cana-431	31	19	insulin	insulin	NOUN
cana-431	31	20	resistance	resistance	NOUN
cana-431	31	21	that	that	PRON
cana-431	31	22	chronic	chronic	ADJ
cana-431	31	23	low	low	ADJ
cana-431	31	24	-	-	PUNCT
cana-431	31	25	grade	grade	NOUN
cana-431	31	26	inflammation	inflammation	NOUN
cana-431	31	27	may	may	AUX
cana-431	31	28	play	play	VERB
cana-431	31	29	a	a	DET
cana-431	31	30	role	role	NOUN
cana-431	31	31	.	.	PUNCT
cana-431	32	1	due	due	ADP
cana-431	32	2	to	to	ADP
cana-431	32	3	insufficient	insufficient	ADJ
cana-431	32	4	secretion	secretion	NOUN
cana-431	32	5	of	of	ADP
cana-431	32	6	insulin	insulin	NOUN
cana-431	32	7	,	,	PUNCT
cana-431	32	8	blood	blood	NOUN
cana-431	32	9	glucose	glucose	NOUN
cana-431	32	10	levels	level	NOUN
cana-431	32	11	rise	rise	VERB
cana-431	32	12	.	.	PUNCT
cana-431	33	1	which	which	PRON
cana-431	33	2	is	be	AUX
cana-431	33	3	the	the	DET
cana-431	33	4	body	body	NOUN
cana-431	33	5	's	's	PART
cana-431	33	6	cells	cell	NOUN
cana-431	33	7	ineffective	ineffective	ADJ
cana-431	33	8	response	response	NOUN
cana-431	33	9	to	to	ADP
cana-431	33	10	insulin	insulin	NOUN
cana-431	33	11	.	.	PUNCT
cana-431	34	1	insulin	insulin	NOUN
cana-431	34	2	resistance	resistance	NOUN
cana-431	34	3	is	be	AUX
cana-431	34	4	generally	generally	ADV
cana-431	34	5	associated	associate	VERB
cana-431	34	6	with	with	ADP
cana-431	34	7	the	the	DET
cana-431	34	8	obesity	obesity	NOUN
cana-431	34	9	.	.	PUNCT
cana-431	35	1	hence	hence	ADV
cana-431	35	2	obesity	obesity	NOUN
cana-431	35	3	is	be	AUX
cana-431	35	4	also	also	ADV
cana-431	35	5	responsible	responsible	ADJ
cana-431	35	6	for	for	ADP
cana-431	35	7	type	type	NOUN
cana-431	35	8	2	2	NUM
cana-431	35	9	diabetes	diabetes	NOUN
cana-431	35	10	.	.	PUNCT
cana-431	36	1	not	not	PART
cana-431	36	2	all	all	PRON
cana-431	36	3	obese	obese	ADJ
cana-431	36	4	human	human	ADJ
cana-431	36	5	being	being	AUX
cana-431	36	6	suffered	suffer	VERB
cana-431	36	7	from	from	ADP
cana-431	36	8	type	type	NOUN
cana-431	36	9	2	2	NUM
cana-431	36	10	diabetes	diabetes	NOUN
cana-431	36	11	as	as	SCONJ
cana-431	36	12	it	it	PRON
cana-431	36	13	depends	depend	VERB
cana-431	36	14	on	on	ADP
cana-431	36	15	immunity	immunity	NOUN
cana-431	36	16	of	of	ADP
cana-431	36	17	persons	person	NOUN
cana-431	36	18	and	and	CCONJ
cana-431	36	19	heredity	heredity	NOUN
cana-431	36	20	[	[	X
cana-431	36	21	7	7	NUM
cana-431	36	22	]	]	PUNCT
cana-431	36	23	.	.	PUNCT
cana-431	37	1	gestational	gestational	ADJ
cana-431	37	2	diabetes	diabetes	NOUN
cana-431	37	3	is	be	AUX
cana-431	37	4	again	again	ADV
cana-431	37	5	one	one	NUM
cana-431	37	6	of	of	ADP
cana-431	37	7	the	the	DET
cana-431	37	8	types	type	NOUN
cana-431	37	9	of	of	ADP
cana-431	37	10	the	the	DET
cana-431	37	11	diabetes	diabetes	NOUN
cana-431	37	12	but	but	CCONJ
cana-431	37	13	it	it	PRON
cana-431	37	14	occurs	occur	VERB
cana-431	37	15	only	only	ADV
cana-431	37	16	during	during	ADP
cana-431	37	17	the	the	DET
cana-431	37	18	stage	stage	NOUN
cana-431	37	19	of	of	ADP
cana-431	37	20	pregnancy	pregnancy	NOUN
cana-431	37	21	and	and	CCONJ
cana-431	37	22	it	it	PRON
cana-431	37	23	goes	go	VERB
cana-431	37	24	away	away	ADV
cana-431	37	25	when	when	SCONJ
cana-431	37	26	baby	baby	NOUN
cana-431	37	27	is	be	AUX
cana-431	37	28	born	bear	VERB
cana-431	37	29	,	,	PUNCT
cana-431	37	30	later	later	ADV
cana-431	37	31	on	on	ADV
cana-431	37	32	it	it	PRON
cana-431	37	33	can	can	AUX
cana-431	37	34	convert	convert	VERB
cana-431	37	35	to	to	ADP
cana-431	37	36	the	the	DET
cana-431	37	37	type	type	NOUN
cana-431	37	38	2	2	NUM
cana-431	37	39	diabetes	diabetes	NOUN
cana-431	37	40	depending	depend	VERB
cana-431	37	41	upon	upon	SCONJ
cana-431	37	42	the	the	DET
cana-431	37	43	immune	immune	ADJ
cana-431	37	44	system	system	NOUN
cana-431	37	45	level	level	NOUN
cana-431	37	46	[	[	X
cana-431	37	47	8	8	NUM
cana-431	37	48	]	]	PUNCT
cana-431	37	49	.	.	PUNCT
cana-431	38	1	study	study	NOUN
cana-431	38	2	of	of	ADP
cana-431	38	3	diabetes	diabetes	NOUN
cana-431	38	4	is	be	AUX
cana-431	38	5	most	most	ADV
cana-431	38	6	important	important	ADJ
cana-431	38	7	as	as	ADP
cana-431	38	8	now	now	ADV
cana-431	38	9	a	a	DET
cana-431	38	10	days	day	NOUN
cana-431	38	11	its	its	PRON
cana-431	38	12	frequently	frequently	ADV
cana-431	38	13	occurred	occur	VERB
cana-431	38	14	is	be	AUX
cana-431	38	15	all	all	DET
cana-431	38	16	age	age	NOUN
cana-431	38	17	levels	level	NOUN
cana-431	38	18	and	and	CCONJ
cana-431	38	19	also	also	ADV
cana-431	38	20	the	the	DET
cana-431	38	21	human	human	ADJ
cana-431	38	22	being	being	AUX
cana-431	38	23	suffered	suffer	VERB
cana-431	38	24	from	from	ADP
cana-431	38	25	diabetes	diabetes	NOUN
cana-431	38	26	having	have	VERB
cana-431	38	27	different	different	ADJ
cana-431	38	28	range	range	NOUN
cana-431	38	29	of	of	ADP
cana-431	38	30	glucose	glucose	NOUN
cana-431	38	31	level	level	NOUN
cana-431	38	32	(	(	PUNCT
cana-431	38	33	pre	pre	X
cana-431	38	34	meal	meal	NOUN
cana-431	38	35	or	or	CCONJ
cana-431	38	36	post	post	NOUN
cana-431	38	37	meal	meal	NOUN
cana-431	38	38	)	)	PUNCT
cana-431	38	39	,	,	PUNCT
cana-431	38	40	it	it	PRON
cana-431	38	41	varies	vary	VERB
cana-431	38	42	person	person	NOUN
cana-431	38	43	to	to	ADP
cana-431	38	44	person	person	NOUN
cana-431	38	45	.	.	PUNCT
cana-431	39	1	the	the	DET
cana-431	39	2	reading	reading	NOUN
cana-431	39	3	regarding	regard	VERB
cana-431	39	4	the	the	DET
cana-431	39	5	diabetes	diabetes	NOUN
cana-431	39	6	of	of	ADP
cana-431	39	7	a	a	DET
cana-431	39	8	single	single	ADJ
cana-431	39	9	person	person	NOUN
cana-431	39	10	also	also	ADV
cana-431	39	11	varies	vary	VERB
cana-431	39	12	day	day	NOUN
cana-431	39	13	by	by	ADP
cana-431	39	14	day	day	NOUN
cana-431	39	15	.	.	PUNCT
cana-431	40	1	1.2	1.2	NUM
cana-431	40	2	objective	objective	NOUN
cana-431	40	3	:	:	PUNCT
cana-431	40	4	the	the	DET
cana-431	40	5	next	next	ADJ
cana-431	40	6	step	step	NOUN
cana-431	40	7	in	in	ADP
cana-431	40	8	an	an	DET
cana-431	40	9	optimization	optimization	NOUN
cana-431	40	10	method	method	NOUN
cana-431	40	11	is	be	AUX
cana-431	40	12	to	to	PART
cana-431	40	13	assign	assign	VERB
cana-431	40	14	values	value	NOUN
cana-431	40	15	to	to	ADP
cana-431	40	16	the	the	DET
cana-431	40	17	unknowns	unknown	NOUN
cana-431	40	18	from	from	ADP
cana-431	40	19	the	the	DET
cana-431	40	20	permitted	permit	VERB
cana-431	40	21	domain	domain	NOUN
cana-431	40	22	so	so	SCONJ
cana-431	40	23	that	that	SCONJ
cana-431	40	24	all	all	DET
cana-431	40	25	constraints	constraint	NOUN
cana-431	40	26	are	be	AUX
cana-431	40	27	satisfied	satisfied	ADJ
cana-431	40	28	and	and	CCONJ
cana-431	40	29	the	the	DET
cana-431	40	30	objective	objective	ADJ
cana-431	40	31	function	function	NOUN
cana-431	40	32	is	be	AUX
cana-431	40	33	optimized	optimize	VERB
cana-431	40	34	.	.	PUNCT
cana-431	41	1	the	the	DET
cana-431	41	2	optimization	optimization	NOUN
cana-431	41	3	method	method	NOUN
cana-431	41	4	looks	look	VERB
cana-431	41	5	for	for	ADP
cana-431	41	6	a	a	DET
cana-431	41	7	solution	solution	NOUN
cana-431	41	8	in	in	ADP
cana-431	41	9	a	a	DET
cana-431	41	10	search	search	NOUN
cana-431	41	11	space	space	NOUN
cana-431	41	12	,	,	PUNCT
cana-431	41	13	s	s	PROPN
cana-431	41	14	of	of	ADP
cana-431	41	15	solutions	solution	NOUN
cana-431	41	16	,	,	PUNCT
cana-431	41	17	in	in	ADP
cana-431	41	18	order	order	NOUN
cana-431	41	19	to	to	PART
cana-431	41	20	accomplish	accomplish	VERB
cana-431	41	21	this	this	DET
cana-431	41	22	goal	goal	NOUN
cana-431	41	23	.	.	PUNCT
cana-431	42	1	in	in	ADP
cana-431	42	2	the	the	DET
cana-431	42	3	context	context	NOUN
cana-431	42	4	of	of	ADP
cana-431	42	5	a	a	DET
cana-431	42	6	diabetes	diabetes	NOUN
cana-431	42	7	model	model	NOUN
cana-431	42	8	,	,	PUNCT
cana-431	42	9	parameter	parameter	NOUN
cana-431	42	10	estimation	estimation	NOUN
cana-431	42	11	involves	involve	VERB
cana-431	42	12	determining	determine	VERB
cana-431	42	13	the	the	DET
cana-431	42	14	values	value	NOUN
cana-431	42	15	of	of	ADP
cana-431	42	16	the	the	DET
cana-431	42	17	model	model	NOUN
cana-431	42	18	's	's	PART
cana-431	42	19	parameters	parameter	NOUN
cana-431	42	20	to	to	PART
cana-431	42	21	best	well	ADV
cana-431	42	22	fit	fit	VERB
cana-431	42	23	the	the	DET
cana-431	42	24	available	available	ADJ
cana-431	42	25	data	datum	NOUN
cana-431	42	26	.	.	PUNCT
cana-431	43	1	diabetes	diabetes	NOUN
cana-431	43	2	models	model	NOUN
cana-431	43	3	can	can	AUX
cana-431	43	4	range	range	VERB
cana-431	43	5	from	from	ADP
cana-431	43	6	simple	simple	ADJ
cana-431	43	7	to	to	ADP
cana-431	43	8	complex	complex	ADJ
cana-431	43	9	,	,	PUNCT
cana-431	43	10	often	often	ADV
cana-431	43	11	involving	involve	VERB
cana-431	43	12	mathematical	mathematical	ADJ
cana-431	43	13	equations	equation	NOUN
cana-431	43	14	that	that	PRON
cana-431	43	15	describe	describe	VERB
cana-431	43	16	the	the	DET
cana-431	43	17	relationships	relationship	NOUN
cana-431	43	18	between	between	ADP
cana-431	43	19	variables	variable	NOUN
cana-431	43	20	related	relate	VERB
cana-431	43	21	to	to	ADP
cana-431	43	22	glucose	glucose	NOUN
cana-431	43	23	and	and	CCONJ
cana-431	43	24	insulin	insulin	NOUN
cana-431	43	25	dynamics	dynamic	NOUN
cana-431	43	26	[	[	X
cana-431	43	27	9	9	NUM
cana-431	43	28	]	]	PUNCT
cana-431	43	29	.	.	PUNCT
cana-431	44	1	multi	multi	ADJ
cana-431	44	2	-	-	ADJ
cana-431	44	3	objective	objective	ADJ
cana-431	44	4	optimization	optimization	NOUN
cana-431	44	5	is	be	AUX
cana-431	44	6	a	a	DET
cana-431	44	7	part	part	NOUN
cana-431	44	8	of	of	ADP
cana-431	44	9	multiple	multiple	ADJ
cana-431	44	10	-	-	PUNCT
cana-431	44	11	criteria	criterion	NOUN
cana-431	44	12	decision	decision	NOUN
cana-431	44	13	making	make	VERB
cana-431	44	14	that	that	PRON
cana-431	44	15	includes	include	VERB
cana-431	44	16	mathematical	mathematical	ADJ
cana-431	44	17	optimization	optimization	NOUN
cana-431	44	18	problems	problem	NOUN
cana-431	44	19	having	have	VERB
cana-431	44	20	multiple	multiple	ADJ
cana-431	44	21	objective	objective	ADJ
cana-431	44	22	functions	function	NOUN
cana-431	44	23	that	that	PRON
cana-431	44	24	must	must	AUX
cana-431	44	25	be	be	AUX
cana-431	44	26	maximized	maximize	VERB
cana-431	44	27	simultaneously	simultaneously	ADV
cana-431	44	28	.	.	PUNCT
cana-431	45	1	in	in	ADP
cana-431	45	2	numerous	numerous	ADJ
cana-431	45	3	biological	biological	ADJ
cana-431	45	4	domains	domain	NOUN
cana-431	45	5	,	,	PUNCT
cana-431	45	6	multi	multi	ADJ
cana-431	45	7	-	-	ADJ
cana-431	45	8	objective	objective	ADJ
cana-431	45	9	vector	vector	NOUN
cana-431	45	10	optimization	optimization	NOUN
cana-431	45	11	has	have	AUX
cana-431	45	12	been	be	AUX
cana-431	45	13	utilized	utilize	VERB
cana-431	45	14	[	[	PUNCT
cana-431	45	15	10	10	NUM
cana-431	45	16	]	]	PUNCT
cana-431	45	17	.	.	PUNCT
cana-431	46	1	when	when	SCONJ
cana-431	46	2	creating	create	VERB
cana-431	46	3	a	a	DET
cana-431	46	4	mathematical	mathematical	ADJ
cana-431	46	5	model	model	NOUN
cana-431	46	6	for	for	ADP
cana-431	46	7	immunotherapy	immunotherapy	NOUN
cana-431	46	8	,	,	PUNCT
cana-431	46	9	it	it	PRON
cana-431	46	10	's	be	AUX
cana-431	46	11	essential	essential	ADJ
cana-431	46	12	to	to	PART
cana-431	46	13	carefully	carefully	ADV
cana-431	46	14	define	define	VERB
cana-431	46	15	the	the	DET
cana-431	46	16	decision	decision	NOUN
cana-431	46	17	variables	variable	NOUN
cana-431	46	18	based	base	VERB
cana-431	46	19	on	on	ADP
cana-431	46	20	the	the	DET
cana-431	46	21	specific	specific	ADJ
cana-431	46	22	goals	goal	NOUN
cana-431	46	23	of	of	ADP
cana-431	46	24	the	the	DET
cana-431	46	25	model	model	NOUN
cana-431	46	26	,	,	PUNCT
cana-431	46	27	whether	whether	SCONJ
cana-431	46	28	it	it	PRON
cana-431	46	29	's	be	AUX
cana-431	46	30	optimizing	optimize	VERB
cana-431	46	31	treatment	treatment	NOUN
cana-431	46	32	outcomes	outcome	NOUN
cana-431	46	33	,	,	PUNCT
cana-431	46	34	resource	resource	NOUN
cana-431	46	35	allocation	allocation	NOUN
cana-431	46	36	,	,	PUNCT
cana-431	46	37	or	or	CCONJ
cana-431	46	38	other	other	ADJ
cana-431	46	39	objectives	objective	NOUN
cana-431	46	40	.	.	PUNCT
cana-431	47	1	additionally	additionally	ADV
cana-431	47	2	,	,	PUNCT
cana-431	47	3	the	the	DET
cana-431	47	4	model	model	NOUN
cana-431	47	5	may	may	AUX
cana-431	47	6	include	include	VERB
cana-431	47	7	constraints	constraint	NOUN
cana-431	47	8	,	,	PUNCT
cana-431	47	9	such	such	ADJ
cana-431	47	10	as	as	ADP
cana-431	47	11	safety	safety	NOUN
cana-431	47	12	limits	limit	NOUN
cana-431	47	13	and	and	CCONJ
cana-431	47	14	ethical	ethical	ADJ
cana-431	47	15	considerations	consideration	NOUN
cana-431	47	16	,	,	PUNCT
cana-431	47	17	to	to	PART
cana-431	47	18	ensure	ensure	VERB
cana-431	47	19	realistic	realistic	ADJ
cana-431	47	20	and	and	CCONJ
cana-431	47	21	practical	practical	ADJ
cana-431	47	22	solutions	solution	NOUN
cana-431	47	23	.	.	PUNCT
cana-431	48	1	identifying	identify	VERB
cana-431	48	2	parameters	parameter	NOUN
cana-431	48	3	for	for	ADP
cana-431	48	4	a	a	DET
cana-431	48	5	number	number	NOUN
cana-431	48	6	of	of	ADP
cana-431	48	7	associated	associate	VERB
cana-431	48	8	diseases	disease	NOUN
cana-431	48	9	and	and	CCONJ
cana-431	48	10	using	use	VERB
cana-431	48	11	those	those	DET
cana-431	48	12	parameters	parameter	NOUN
cana-431	48	13	to	to	PART
cana-431	48	14	compute	compute	VERB
cana-431	48	15	usefully	usefully	ADV
cana-431	48	16	the	the	DET
cana-431	48	17	impact	impact	NOUN
cana-431	48	18	of	of	ADP
cana-431	48	19	a	a	DET
cana-431	48	20	big	big	ADJ
cana-431	48	21	immunization	immunization	NOUN
cana-431	48	22	program	program	NOUN
cana-431	48	23	.	.	PUNCT
cana-431	49	1	multiline	multiline	PROPN
cana-431	49	2	objective	objective	ADJ
cana-431	49	3	functions	function	NOUN
cana-431	49	4	typically	typically	ADV
cana-431	49	5	refer	refer	VERB
cana-431	49	6	to	to	ADP
cana-431	49	7	optimization	optimization	NOUN
cana-431	49	8	problems	problem	NOUN
cana-431	49	9	with	with	ADP
cana-431	49	10	objectives	objective	NOUN
cana-431	49	11	that	that	PRON
cana-431	49	12	span	span	VERB
cana-431	49	13	multiple	multiple	ADJ
cana-431	49	14	lines	line	NOUN
cana-431	49	15	or	or	CCONJ
cana-431	49	16	equations	equation	NOUN
cana-431	50	1	[	[	X
cana-431	50	2	11	11	NUM
cana-431	50	3	]	]	PUNCT
cana-431	50	4	.	.	PUNCT
cana-431	51	1	in	in	ADP
cana-431	51	2	mathematical	mathematical	ADJ
cana-431	51	3	optimization	optimization	NOUN
cana-431	51	4	,	,	PUNCT
cana-431	51	5	an	an	DET
cana-431	51	6	objective	objective	ADJ
cana-431	51	7	function	function	NOUN
cana-431	51	8	is	be	AUX
cana-431	51	9	a	a	DET
cana-431	51	10	function	function	NOUN
cana-431	51	11	that	that	PRON
cana-431	51	12	is	be	AUX
cana-431	51	13	to	to	PART
cana-431	51	14	be	be	AUX
cana-431	51	15	communications	communication	NOUN
cana-431	51	16	on	on	ADP
cana-431	51	17	applied	apply	VERB
cana-431	51	18	nonlinear	nonlinear	ADJ
cana-431	51	19	analysis	analysis	NOUN
cana-431	51	20	issn	issn	NOUN
cana-431	51	21	:	:	PUNCT
cana-431	51	22	1074	1074	NUM
cana-431	51	23	-	-	PUNCT
cana-431	51	24	133x	133x	NUM
cana-431	51	25	vol	vol	NOUN
cana-431	51	26	31	31	NUM
cana-431	51	27	no	no	NOUN
cana-431	51	28	.	.	NOUN
cana-431	51	29	1	1	NUM
cana-431	51	30	(	(	PUNCT
cana-431	51	31	2024	2024	NUM
cana-431	51	32	)	)	PUNCT
cana-431	51	33	289	289	NUM
cana-431	51	34	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	51	35	optimized	optimize	VERB
cana-431	51	36	,	,	PUNCT
cana-431	51	37	either	either	CCONJ
cana-431	51	38	minimized	minimized	ADJ
cana-431	51	39	or	or	CCONJ
cana-431	51	40	maximized	maximize	VERB
cana-431	51	41	,	,	PUNCT
cana-431	51	42	by	by	ADP
cana-431	51	43	choosing	choose	VERB
cana-431	51	44	the	the	DET
cana-431	51	45	values	value	NOUN
cana-431	51	46	of	of	ADP
cana-431	51	47	the	the	DET
cana-431	51	48	decision	decision	NOUN
cana-431	51	49	variables	variable	NOUN
cana-431	51	50	.	.	PUNCT
cana-431	52	1	when	when	SCONJ
cana-431	52	2	the	the	DET
cana-431	52	3	objective	objective	ADJ
cana-431	52	4	function	function	NOUN
cana-431	52	5	involves	involve	VERB
cana-431	52	6	multiple	multiple	ADJ
cana-431	52	7	criteria	criterion	NOUN
cana-431	52	8	or	or	CCONJ
cana-431	52	9	components	component	NOUN
cana-431	52	10	[	[	X
cana-431	52	11	12	12	NUM
cana-431	52	12	]	]	PUNCT
cana-431	52	13	.	.	PUNCT
cana-431	53	1	multistage	multistage	NOUN
cana-431	53	2	modelling	modelling	NOUN
cana-431	53	3	explore	explore	VERB
cana-431	53	4	the	the	DET
cana-431	53	5	potential	potential	NOUN
cana-431	53	6	for	for	ADP
cana-431	53	7	developing	develop	VERB
cana-431	53	8	multistage	multistage	NOUN
cana-431	53	9	models	model	NOUN
cana-431	53	10	that	that	PRON
cana-431	53	11	integrate	integrate	VERB
cana-431	53	12	different	different	ADJ
cana-431	53	13	levels	level	NOUN
cana-431	53	14	of	of	ADP
cana-431	53	15	biological	biological	ADJ
cana-431	53	16	information	information	NOUN
cana-431	53	17	to	to	PART
cana-431	53	18	capture	capture	VERB
cana-431	53	19	complexity	complexity	NOUN
cana-431	53	20	.	.	PUNCT
cana-431	54	1	in	in	ADP
cana-431	54	2	mathematical	mathematical	ADJ
cana-431	54	3	modelling	modelling	NOUN
cana-431	54	4	,	,	PUNCT
cana-431	54	5	decision	decision	NOUN
cana-431	54	6	variables	variable	NOUN
cana-431	54	7	represent	represent	VERB
cana-431	54	8	the	the	DET
cana-431	54	9	quantities	quantity	NOUN
cana-431	54	10	or	or	CCONJ
cana-431	54	11	factors	factor	NOUN
cana-431	54	12	that	that	PRON
cana-431	54	13	decision	decision	NOUN
cana-431	54	14	-	-	PUNCT
cana-431	54	15	makers	maker	NOUN
cana-431	54	16	can	can	AUX
cana-431	54	17	control	control	VERB
cana-431	54	18	or	or	CCONJ
cana-431	54	19	manipulate	manipulate	VERB
cana-431	54	20	to	to	PART
cana-431	54	21	optimize	optimize	VERB
cana-431	54	22	a	a	DET
cana-431	54	23	certain	certain	ADJ
cana-431	54	24	outcome	outcome	NOUN
cana-431	54	25	.	.	PUNCT
cana-431	55	1	in	in	ADP
cana-431	55	2	the	the	DET
cana-431	55	3	context	context	NOUN
cana-431	55	4	of	of	ADP
cana-431	55	5	immunotherapy	immunotherapy	NOUN
cana-431	55	6	,	,	PUNCT
cana-431	55	7	the	the	DET
cana-431	55	8	decision	decision	NOUN
cana-431	55	9	variables	variable	NOUN
cana-431	55	10	may	may	AUX
cana-431	55	11	vary	vary	VERB
cana-431	55	12	depending	depend	VERB
cana-431	55	13	on	on	ADP
cana-431	55	14	the	the	DET
cana-431	55	15	specific	specific	ADJ
cana-431	55	16	goals	goal	NOUN
cana-431	55	17	,	,	PUNCT
cana-431	55	18	constraints	constraint	NOUN
cana-431	55	19	,	,	PUNCT
cana-431	55	20	and	and	CCONJ
cana-431	55	21	characteristics	characteristic	NOUN
cana-431	55	22	of	of	ADP
cana-431	55	23	the	the	DET
cana-431	55	24	model[13	model[13	NOUN
cana-431	55	25	]	]	PUNCT
cana-431	55	26	.	.	PUNCT
cana-431	56	1	here	here	ADV
cana-431	56	2	are	be	AUX
cana-431	56	3	some	some	DET
cana-431	56	4	potential	potential	ADJ
cana-431	56	5	decision	decision	NOUN
cana-431	56	6	variables	variable	NOUN
cana-431	56	7	of	of	ADP
cana-431	56	8	immunotherapy	immunotherapy	NOUN
cana-431	56	9	related	relate	VERB
cana-431	56	10	to	to	ADP
cana-431	56	11	the	the	DET
cana-431	56	12	diabetes	diabetes	NOUN
cana-431	56	13	considered	consider	VERB
cana-431	56	14	.	.	PUNCT
cana-431	57	1	glucose	glucose	NOUN
cana-431	57	2	levels	level	NOUN
cana-431	57	3	of	of	ADP
cana-431	57	4	patients	patient	NOUN
cana-431	57	5	are	be	AUX
cana-431	57	6	not	not	PART
cana-431	57	7	constant	constant	ADJ
cana-431	57	8	,	,	PUNCT
cana-431	57	9	even	even	ADV
cana-431	57	10	individual	individual	ADJ
cana-431	57	11	patents	patent	NOUN
cana-431	57	12	glucose	glucose	NOUN
cana-431	57	13	levels	level	NOUN
cana-431	57	14	are	be	AUX
cana-431	57	15	not	not	PART
cana-431	57	16	constant	constant	ADJ
cana-431	57	17	its	its	PRON
cana-431	57	18	always	always	ADV
cana-431	57	19	varies	vary	VERB
cana-431	57	20	according	accord	VERB
cana-431	57	21	to	to	ADP
cana-431	57	22	the	the	DET
cana-431	57	23	intake	intake	NOUN
cana-431	57	24	of	of	ADP
cana-431	57	25	food	food	NOUN
cana-431	57	26	and	and	CCONJ
cana-431	57	27	the	the	DET
cana-431	57	28	physical	physical	ADJ
cana-431	57	29	activities	activity	NOUN
cana-431	57	30	.	.	PUNCT
cana-431	58	1	so	so	ADV
cana-431	58	2	,	,	PUNCT
cana-431	58	3	treatment	treatment	NOUN
cana-431	58	4	on	on	ADP
cana-431	58	5	a	a	DET
cana-431	58	6	specific	specific	ADJ
cana-431	58	7	disease	disease	NOUN
cana-431	58	8	is	be	AUX
cana-431	58	9	also	also	ADV
cana-431	58	10	varies	vary	VERB
cana-431	58	11	according	accord	VERB
cana-431	58	12	to	to	ADP
cana-431	58	13	glucose	glucose	NOUN
cana-431	58	14	level	level	NOUN
cana-431	58	15	,	,	PUNCT
cana-431	58	16	insulin	insulin	NOUN
cana-431	58	17	secretion	secretion	NOUN
cana-431	58	18	,	,	PUNCT
cana-431	58	19	and	and	CCONJ
cana-431	58	20	immunity	immunity	NOUN
cana-431	58	21	of	of	ADP
cana-431	58	22	the	the	DET
cana-431	58	23	person	person	NOUN
cana-431	58	24	.	.	PUNCT
cana-431	59	1	1	1	X
cana-431	59	2	.	.	X
cana-431	59	3	dosage	dosage	NOUN
cana-431	59	4	levels	level	NOUN
cana-431	59	5	:	:	PUNCT
cana-431	59	6	decision	decision	NOUN
cana-431	59	7	variable	variable	NOUN
cana-431	59	8	:	:	PUNCT
cana-431	59	9	the	the	DET
cana-431	59	10	amount	amount	NOUN
cana-431	59	11	or	or	CCONJ
cana-431	59	12	concentration	concentration	NOUN
cana-431	59	13	of	of	ADP
cana-431	59	14	the	the	DET
cana-431	59	15	immunotherapy	immunotherapy	NOUN
cana-431	59	16	drug	drug	NOUN
cana-431	59	17	administered	administer	VERB
cana-431	59	18	to	to	ADP
cana-431	59	19	the	the	DET
cana-431	59	20	patient	patient	NOUN
cana-431	59	21	.	.	PUNCT
cana-431	60	1	dosage	dosage	NOUN
cana-431	60	2	may	may	AUX
cana-431	60	3	vary	vary	VERB
cana-431	60	4	according	accord	VERB
cana-431	60	5	to	to	ADP
cana-431	60	6	glucose	glucose	NOUN
cana-431	60	7	level	level	NOUN
cana-431	60	8	of	of	ADP
cana-431	60	9	person	person	NOUN
cana-431	60	10	.	.	PUNCT
cana-431	61	1	if	if	SCONJ
cana-431	61	2	glucose	glucose	NOUN
cana-431	61	3	concentration	concentration	NOUN
cana-431	61	4	is	be	AUX
cana-431	61	5	high	high	ADJ
cana-431	61	6	insulin	insulin	NOUN
cana-431	61	7	secretion	secretion	NOUN
cana-431	61	8	is	be	AUX
cana-431	61	9	low	low	ADJ
cana-431	61	10	then	then	ADV
cana-431	61	11	person	person	NOUN
cana-431	61	12	need	need	VERB
cana-431	61	13	to	to	PART
cana-431	61	14	take	take	VERB
cana-431	61	15	more	more	ADJ
cana-431	61	16	dosages	dosage	NOUN
cana-431	61	17	of	of	ADP
cana-431	61	18	medicine	medicine	NOUN
cana-431	61	19	to	to	PART
cana-431	61	20	control	control	VERB
cana-431	61	21	the	the	DET
cana-431	61	22	glucose	glucose	NOUN
cana-431	61	23	level	level	NOUN
cana-431	61	24	.	.	PUNCT
cana-431	62	1	sometime	sometime	ADJ
cana-431	62	2	high	high	ADJ
cana-431	62	3	intake	intake	NOUN
cana-431	62	4	of	of	ADP
cana-431	62	5	medicines	medicine	NOUN
cana-431	62	6	may	may	AUX
cana-431	62	7	affect	affect	VERB
cana-431	62	8	on	on	ADP
cana-431	62	9	other	other	ADJ
cana-431	62	10	organs	organ	NOUN
cana-431	62	11	so	so	SCONJ
cana-431	62	12	its	its	PRON
cana-431	62	13	objectives	objective	NOUN
cana-431	62	14	should	should	AUX
cana-431	62	15	be	be	AUX
cana-431	62	16	to	to	PART
cana-431	62	17	minimize	minimize	VERB
cana-431	62	18	the	the	DET
cana-431	62	19	side	side	NOUN
cana-431	62	20	effects	effect	NOUN
cana-431	62	21	.	.	PUNCT
cana-431	63	1	objective	objective	NOUN
cana-431	63	2	:	:	PUNCT
cana-431	63	3	minimizing	minimize	VERB
cana-431	63	4	potential	potential	ADJ
cana-431	63	5	side	side	NOUN
cana-431	63	6	effect	effect	NOUN
cana-431	63	7	.	.	PUNCT
cana-431	64	1	2.duration	2.duration	NUM
cana-431	64	2	of	of	ADP
cana-431	64	3	treatment	treatment	NOUN
cana-431	64	4	:	:	PUNCT
cana-431	64	5	if	if	SCONJ
cana-431	64	6	the	the	DET
cana-431	64	7	immunity	immunity	NOUN
cana-431	64	8	of	of	ADP
cana-431	64	9	one	one	NUM
cana-431	64	10	of	of	ADP
cana-431	64	11	the	the	DET
cana-431	64	12	persons	person	NOUN
cana-431	64	13	is	be	AUX
cana-431	64	14	strong	strong	ADJ
cana-431	64	15	then	then	ADV
cana-431	64	16	it	it	PRON
cana-431	64	17	helps	help	VERB
cana-431	64	18	to	to	PART
cana-431	64	19	cure	cure	VERB
cana-431	64	20	the	the	DET
cana-431	64	21	diseases	disease	NOUN
cana-431	64	22	within	within	ADP
cana-431	64	23	short	short	ADJ
cana-431	64	24	period	period	NOUN
cana-431	64	25	of	of	ADP
cana-431	64	26	time	time	NOUN
cana-431	64	27	.	.	PUNCT
cana-431	65	1	but	but	CCONJ
cana-431	65	2	if	if	SCONJ
cana-431	65	3	the	the	DET
cana-431	65	4	diabetes	diabetes	NOUN
cana-431	65	5	damaged	damage	VERB
cana-431	65	6	the	the	DET
cana-431	65	7	one	one	NUM
cana-431	65	8	of	of	ADP
cana-431	65	9	the	the	DET
cana-431	65	10	essential	essential	ADJ
cana-431	65	11	organs	organ	NOUN
cana-431	65	12	of	of	ADP
cana-431	65	13	the	the	DET
cana-431	65	14	human	human	ADJ
cana-431	65	15	body	body	NOUN
cana-431	65	16	or	or	CCONJ
cana-431	65	17	it	it	PRON
cana-431	65	18	attacked	attack	VERB
cana-431	65	19	vigorously	vigorously	ADV
cana-431	65	20	on	on	ADP
cana-431	65	21	one	one	NUM
cana-431	65	22	of	of	ADP
cana-431	65	23	the	the	DET
cana-431	65	24	body	body	NOUN
cana-431	65	25	parts	part	NOUN
cana-431	65	26	then	then	ADV
cana-431	65	27	immune	immune	ADJ
cana-431	65	28	system	system	NOUN
cana-431	65	29	takes	take	VERB
cana-431	65	30	more	more	ADJ
cana-431	65	31	times	time	NOUN
cana-431	65	32	to	to	PART
cana-431	65	33	cure	cure	VERB
cana-431	65	34	the	the	DET
cana-431	65	35	diseases	disease	NOUN
cana-431	65	36	.	.	PUNCT
cana-431	66	1	decision	decision	NOUN
cana-431	66	2	variable	variable	NOUN
cana-431	66	3	:	:	PUNCT
cana-431	66	4	the	the	DET
cana-431	66	5	total	total	ADJ
cana-431	66	6	duration	duration	NOUN
cana-431	66	7	of	of	ADP
cana-431	66	8	the	the	DET
cana-431	66	9	immunotherapy	immunotherapy	NOUN
cana-431	66	10	.	.	PUNCT
cana-431	67	1	objectives	objective	NOUN
cana-431	67	2	:	:	PUNCT
cana-431	67	3	optimize	optimize	VERB
cana-431	67	4	the	the	DET
cana-431	67	5	treatment	treatment	NOUN
cana-431	67	6	duration	duration	NOUN
cana-431	67	7	to	to	PART
cana-431	67	8	achieve	achieve	VERB
cana-431	67	9	sustained	sustained	ADJ
cana-431	67	10	.	.	PUNCT
cana-431	68	1	3.combination	3.combination	NUM
cana-431	68	2	of	of	ADP
cana-431	68	3	therapies	therapy	NOUN
cana-431	68	4	:	:	PUNCT
cana-431	68	5	decision	decision	NOUN
cana-431	68	6	variable	variable	NOUN
cana-431	68	7	:	:	PUNCT
cana-431	68	8	selection	selection	NOUN
cana-431	68	9	and	and	CCONJ
cana-431	68	10	dosage	dosage	NOUN
cana-431	68	11	of	of	ADP
cana-431	68	12	additional	additional	ADJ
cana-431	68	13	therapies	therapy	NOUN
cana-431	68	14	in	in	ADP
cana-431	68	15	combination	combination	NOUN
cana-431	68	16	with	with	ADP
cana-431	68	17	immunotherapy	immunotherapy	NOUN
cana-431	68	18	.	.	PUNCT
cana-431	69	1	objectives	objective	NOUN
cana-431	69	2	:	:	PUNCT
cana-431	69	3	identify	identify	VERB
cana-431	69	4	the	the	DET
cana-431	69	5	most	most	ADV
cana-431	69	6	effective	effective	ADJ
cana-431	69	7	combination	combination	NOUN
cana-431	69	8	of	of	ADP
cana-431	69	9	treatments	treatment	NOUN
cana-431	69	10	to	to	PART
cana-431	69	11	enhance	enhance	VERB
cana-431	69	12	overall	overall	ADJ
cana-431	69	13	therapeutic	therapeutic	ADJ
cana-431	69	14	outcomes	outcome	NOUN
cana-431	69	15	.	.	PUNCT
cana-431	70	1	in	in	ADP
cana-431	70	2	the	the	DET
cana-431	70	3	context	context	NOUN
cana-431	70	4	of	of	ADP
cana-431	70	5	diabetes	diabetes	NOUN
cana-431	70	6	and	and	CCONJ
cana-431	70	7	multistage	multistage	NOUN
cana-431	70	8	mathematical	mathematical	ADJ
cana-431	70	9	modelling	modelling	NOUN
cana-431	70	10	,	,	PUNCT
cana-431	70	11	decision	decision	NOUN
cana-431	70	12	variables	variable	NOUN
cana-431	70	13	can	can	AUX
cana-431	70	14	be	be	AUX
cana-431	70	15	used	use	VERB
cana-431	70	16	to	to	PART
cana-431	70	17	represent	represent	VERB
cana-431	70	18	parameters	parameter	NOUN
cana-431	70	19	that	that	SCONJ
cana-431	70	20	healthcare	healthcare	NOUN
cana-431	70	21	providers	provider	NOUN
cana-431	70	22	adjust	adjust	VERB
cana-431	70	23	to	to	PART
cana-431	70	24	optimize	optimize	VERB
cana-431	70	25	diabetes	diabetes	NOUN
cana-431	70	26	management	management	NOUN
cana-431	70	27	here	here	ADV
cana-431	70	28	are	be	AUX
cana-431	70	29	some	some	DET
cana-431	70	30	potential	potential	ADJ
cana-431	70	31	decision	decision	NOUN
cana-431	70	32	variables	variable	NOUN
cana-431	70	33	related	relate	VERB
cana-431	70	34	to	to	ADP
cana-431	70	35	diabetes	diabetes	NOUN
cana-431	70	36	:	:	PUNCT
cana-431	70	37	diabetes	diabetes	NOUN
cana-431	70	38	is	be	AUX
cana-431	70	39	a	a	DET
cana-431	70	40	long	long	ADJ
cana-431	70	41	-	-	PUNCT
cana-431	70	42	term	term	NOUN
cana-431	70	43	illness	illness	NOUN
cana-431	70	44	that	that	PRON
cana-431	70	45	impacts	impact	VERB
cana-431	70	46	the	the	DET
cana-431	70	47	body	body	NOUN
cana-431	70	48	's	's	PART
cana-431	70	49	utilization	utilization	NOUN
cana-431	70	50	of	of	ADP
cana-431	70	51	glucose	glucose	NOUN
cana-431	70	52	,	,	PUNCT
cana-431	70	53	or	or	CCONJ
cana-431	70	54	blood	blood	NOUN
cana-431	70	55	sugar	sugar	NOUN
cana-431	70	56	.	.	PUNCT
cana-431	71	1	uncontrolled	uncontrolled	ADJ
cana-431	71	2	diabetes	diabetes	NOUN
cana-431	71	3	can	can	AUX
cana-431	71	4	lead	lead	VERB
cana-431	71	5	to	to	ADP
cana-431	71	6	various	various	ADJ
cana-431	71	7	complications	complication	NOUN
cana-431	71	8	and	and	CCONJ
cana-431	71	9	side	side	NOUN
cana-431	71	10	effects	effect	NOUN
cana-431	71	11	.	.	PUNCT
cana-431	72	1	it	it	PRON
cana-431	72	2	's	be	AUX
cana-431	72	3	essential	essential	ADJ
cana-431	72	4	to	to	PART
cana-431	72	5	remember	remember	VERB
cana-431	72	6	that	that	SCONJ
cana-431	72	7	individuals	individual	NOUN
cana-431	72	8	may	may	AUX
cana-431	72	9	experience	experience	VERB
cana-431	72	10	side	side	NOUN
cana-431	72	11	effects	effect	NOUN
cana-431	72	12	differently	differently	ADV
cana-431	72	13	in	in	ADP
cana-431	72	14	terms	term	NOUN
cana-431	72	15	of	of	ADP
cana-431	72	16	intensity	intensity	NOUN
cana-431	72	17	and	and	CCONJ
cana-431	72	18	frequency	frequency	NOUN
cana-431	72	19	.	.	PUNCT
cana-431	73	1	and	and	CCONJ
cana-431	73	2	proper	proper	ADJ
cana-431	73	3	management	management	NOUN
cana-431	73	4	of	of	ADP
cana-431	73	5	diabetes	diabetes	NOUN
cana-431	73	6	can	can	AUX
cana-431	73	7	help	help	VERB
cana-431	73	8	mitigate	mitigate	VERB
cana-431	73	9	these	these	DET
cana-431	73	10	risks	risk	NOUN
cana-431	73	11	.	.	PUNCT
cana-431	74	1	here	here	ADV
cana-431	74	2	are	be	AUX
cana-431	74	3	some	some	DET
cana-431	74	4	common	common	ADJ
cana-431	74	5	side	side	NOUN
cana-431	74	6	effects	effect	NOUN
cana-431	74	7	and	and	CCONJ
cana-431	74	8	complications	complication	NOUN
cana-431	74	9	associated	associate	VERB
cana-431	74	10	with	with	ADP
cana-431	74	11	diabetes	diabetes	NOUN
cana-431	74	12	:	:	PUNCT
cana-431	74	13	communications	communication	NOUN
cana-431	74	14	on	on	ADP
cana-431	74	15	applied	apply	VERB
cana-431	74	16	nonlinear	nonlinear	ADJ
cana-431	74	17	analysis	analysis	NOUN
cana-431	74	18	issn	issn	NOUN
cana-431	74	19	:	:	PUNCT
cana-431	74	20	1074	1074	NUM
cana-431	74	21	-	-	PUNCT
cana-431	74	22	133x	133x	NUM
cana-431	74	23	vol	vol	NOUN
cana-431	74	24	31	31	NUM
cana-431	74	25	no	no	NOUN
cana-431	74	26	.	.	NOUN
cana-431	74	27	1	1	NUM
cana-431	74	28	(	(	PUNCT
cana-431	74	29	2024	2024	NUM
cana-431	74	30	)	)	PUNCT
cana-431	74	31	290	290	NUM
cana-431	74	32	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	74	33	minimize	minimize	NOUN
cana-431	74	34	:	:	PUNCT
cana-431	74	35	{	{	PUNCT
cana-431	74	36	f1(x	f1(x	NOUN
cana-431	74	37	,	,	PUNCT
cana-431	74	38	y	y	PROPN
cana-431	74	39	,	,	PUNCT
cana-431	74	40	z	z	NOUN
cana-431	74	41	)	)	PUNCT
cana-431	74	42	,	,	PUNCT
cana-431	74	43	f2	f2	PROPN
cana-431	74	44	(	(	PUNCT
cana-431	74	45	x	x	X
cana-431	74	46	,	,	PUNCT
cana-431	74	47	y	y	PROPN
cana-431	74	48	,	,	PUNCT
cana-431	74	49	z	z	NOUN
cana-431	74	50	)	)	PUNCT
cana-431	74	51	,	,	PUNCT
cana-431	74	52	f3(x	f3(x	PROPN
cana-431	74	53	,	,	PUNCT
cana-431	74	54	y	y	PROPN
cana-431	74	55	,	,	PUNCT
cana-431	74	56	z	z	NOUN
cana-431	74	57	)	)	PUNCT
cana-431	74	58	,	,	PUNCT
cana-431	74	59	f4(x	f4(x	PROPN
cana-431	74	60	,	,	PUNCT
cana-431	74	61	y	y	PROPN
cana-431	74	62	,	,	PUNCT
cana-431	74	63	z	z	NOUN
cana-431	74	64	)	)	PUNCT
cana-431	74	65	,	,	PUNCT
cana-431	74	66	f5(x	f5(x	PROPN
cana-431	74	67	,	,	PUNCT
cana-431	74	68	y	y	PROPN
cana-431	74	69	,	,	PUNCT
cana-431	74	70	z	z	NOUN
cana-431	74	71	)	)	PUNCT
cana-431	74	72	}	}	PUNCT
cana-431	74	73	subject	subject	ADJ
cana-431	74	74	to	to	ADP
cana-431	74	75	the	the	DET
cana-431	74	76	constraint	constraint	NOUN
cana-431	74	77	:	:	PUNCT
cana-431	74	78	g	g	NOUN
cana-431	74	79	(	(	PUNCT
cana-431	74	80	x	x	PROPN
cana-431	74	81	,	,	PUNCT
cana-431	74	82	y	y	PROPN
cana-431	74	83	,	,	PUNCT
cana-431	74	84	z	z	NOUN
cana-431	74	85	)	)	PUNCT
cana-431	74	86	≤	≤	NOUN
cana-431	74	87	0	0	NUM
cana-431	75	1	and	and	CCONJ
cana-431	75	2	h	h	NOUN
cana-431	75	3	(	(	PUNCT
cana-431	75	4	x	x	X
cana-431	75	5	,	,	PUNCT
cana-431	75	6	y	y	PROPN
cana-431	75	7	,	,	PUNCT
cana-431	75	8	z	z	NOUN
cana-431	75	9	)	)	PUNCT
cana-431	75	10	≤	≤	NOUN
cana-431	75	11	0	0	NUM
cana-431	75	12	cost	cost	NOUN
cana-431	75	13	constraints	constraint	NOUN
cana-431	75	14	:	:	PUNCT
cana-431	75	15	decision	decision	NOUN
cana-431	75	16	variable	variable	NOUN
cana-431	75	17	:	:	PUNCT
cana-431	75	18	consideration	consideration	NOUN
cana-431	75	19	of	of	ADP
cana-431	75	20	the	the	DET
cana-431	75	21	budget	budget	NOUN
cana-431	75	22	or	or	CCONJ
cana-431	75	23	cost	cost	NOUN
cana-431	75	24	constraints	constraint	NOUN
cana-431	75	25	associated	associate	VERB
cana-431	75	26	with	with	ADP
cana-431	75	27	the	the	DET
cana-431	75	28	immunotherapy	immunotherapy	NOUN
cana-431	75	29	.	.	PUNCT
cana-431	76	1	objective	objective	NOUN
cana-431	76	2	:	:	PUNCT
cana-431	76	3	balance	balance	NOUN
cana-431	76	4	treatment	treatment	NOUN
cana-431	76	5	with	with	ADP
cana-431	76	6	the	the	DET
cana-431	76	7	economic	economic	ADJ
cana-431	76	8	feasibility	feasibility	NOUN
cana-431	76	9	of	of	ADP
cana-431	76	10	the	the	DET
cana-431	76	11	immunotherapy	immunotherapy	NOUN
cana-431	76	12	strategy	strategy	NOUN
cana-431	76	13	.	.	PUNCT
cana-431	77	1	treatment	treatment	NOUN
cana-431	77	2	schedule	schedule	NOUN
cana-431	77	3	:	:	PUNCT
cana-431	77	4	decision	decision	NOUN
cana-431	77	5	variable	variable	NOUN
cana-431	77	6	:	:	PUNCT
cana-431	77	7	the	the	DET
cana-431	77	8	timing	timing	NOUN
cana-431	77	9	and	and	CCONJ
cana-431	77	10	frequency	frequency	NOUN
cana-431	77	11	of	of	ADP
cana-431	77	12	immunotherapy	immunotherapy	NOUN
cana-431	77	13	administrations	administration	NOUN
cana-431	77	14	.	.	PUNCT
cana-431	78	1	objectives	objective	NOUN
cana-431	78	2	:	:	PUNCT
cana-431	78	3	develop	develop	VERB
cana-431	78	4	an	an	DET
cana-431	78	5	optimal	optimal	ADJ
cana-431	78	6	treatment	treatment	NOUN
cana-431	78	7	schedule	schedule	NOUN
cana-431	78	8	that	that	PRON
cana-431	78	9	balances	balance	VERB
cana-431	78	10	effectiveness	effectiveness	NOUN
cana-431	78	11	with	with	ADP
cana-431	78	12	patient	patient	ADJ
cana-431	78	13	convenience	convenience	NOUN
cana-431	78	14	.	.	PUNCT
cana-431	79	1	in	in	ADP
cana-431	79	2	this	this	DET
cana-431	79	3	case	case	NOUN
cana-431	79	4	,	,	PUNCT
cana-431	79	5	the	the	DET
cana-431	79	6	objective	objective	NOUN
cana-431	79	7	is	be	AUX
cana-431	79	8	to	to	PART
cana-431	79	9	minimize	minimize	VERB
cana-431	79	10	f1	f1	PROPN
cana-431	79	11	(	(	PUNCT
cana-431	79	12	x	x	NOUN
cana-431	79	13	,	,	PUNCT
cana-431	79	14	y	y	PROPN
cana-431	79	15	,	,	PUNCT
cana-431	79	16	z	z	NOUN
cana-431	79	17	)	)	PUNCT
cana-431	79	18	,	,	PUNCT
cana-431	79	19	f2(x	f2(x	PROPN
cana-431	79	20	,	,	PUNCT
cana-431	79	21	y	y	PROPN
cana-431	79	22	,	,	PUNCT
cana-431	79	23	z	z	NOUN
cana-431	79	24	)	)	PUNCT
cana-431	79	25	,	,	PUNCT
cana-431	79	26	f3	f3	PROPN
cana-431	79	27	(	(	PUNCT
cana-431	79	28	x	x	X
cana-431	79	29	,	,	PUNCT
cana-431	79	30	y	y	PROPN
cana-431	79	31	,	,	PUNCT
cana-431	79	32	z	z	NOUN
cana-431	79	33	)	)	PUNCT
cana-431	79	34	,	,	PUNCT
cana-431	79	35	f4(x	f4(x	PROPN
cana-431	79	36	,	,	PUNCT
cana-431	79	37	y	y	PROPN
cana-431	79	38	,	,	PUNCT
cana-431	79	39	z	z	NOUN
cana-431	79	40	)	)	PUNCT
cana-431	79	41	,	,	PUNCT
cana-431	79	42	f5(x	f5(x	PROPN
cana-431	79	43	,	,	PUNCT
cana-431	79	44	y	y	PROPN
cana-431	79	45	,	,	PUNCT
cana-431	79	46	z	z	NOUN
cana-431	79	47	)	)	PUNCT
cana-431	79	48	simultaneously	simultaneously	ADV
cana-431	79	49	.	.	PUNCT
cana-431	80	1	multiline	multiline	VERB
cana-431	80	2	objective	objective	ADJ
cana-431	80	3	functions	function	NOUN
cana-431	80	4	often	often	ADV
cana-431	80	5	arise	arise	VERB
cana-431	80	6	in	in	ADP
cana-431	80	7	real	real	ADJ
cana-431	80	8	-	-	PUNCT
cana-431	80	9	world	world	NOUN
cana-431	80	10	optimization	optimization	NOUN
cana-431	80	11	problems	problem	NOUN
cana-431	80	12	where	where	SCONJ
cana-431	80	13	there	there	PRON
cana-431	80	14	are	be	VERB
cana-431	80	15	multiple	multiple	ADJ
cana-431	80	16	criteria	criterion	NOUN
cana-431	80	17	to	to	PART
cana-431	80	18	be	be	AUX
cana-431	80	19	considered	consider	VERB
cana-431	80	20	,	,	PUNCT
cana-431	80	21	and	and	CCONJ
cana-431	80	22	the	the	DET
cana-431	80	23	aim	aim	NOUN
cana-431	80	24	is	be	AUX
cana-431	80	25	to	to	PART
cana-431	80	26	find	find	VERB
cana-431	80	27	the	the	DET
cana-431	80	28	set	set	NOUN
cana-431	80	29	of	of	ADP
cana-431	80	30	decision	decision	NOUN
cana-431	80	31	variables	variable	NOUN
cana-431	80	32	which	which	PRON
cana-431	80	33	optimize	optimize	VERB
cana-431	80	34	these	these	DET
cana-431	80	35	criteria	criterion	NOUN
cana-431	80	36	subject	subject	ADJ
cana-431	80	37	to	to	ADP
cana-431	80	38	certain	certain	ADJ
cana-431	80	39	constraints	constraint	NOUN
cana-431	80	40	.	.	PUNCT
cana-431	81	1	the	the	DET
cana-431	81	2	values	value	NOUN
cana-431	81	3	of	of	ADP
cana-431	81	4	the	the	DET
cana-431	81	5	specified	specify	VERB
cana-431	81	6	variables	variable	NOUN
cana-431	81	7	that	that	PRON
cana-431	81	8	produce	produce	VERB
cana-431	81	9	the	the	DET
cana-431	81	10	best	good	ADJ
cana-431	81	11	overall	overall	ADJ
cana-431	81	12	solution	solution	NOUN
cana-431	81	13	that	that	PRON
cana-431	81	14	corresponds	correspond	VERB
cana-431	81	15	with	with	ADP
cana-431	81	16	the	the	DET
cana-431	81	17	objectives	objective	NOUN
cana-431	81	18	are	be	AUX
cana-431	81	19	then	then	ADV
cana-431	81	20	determined	determine	VERB
cana-431	81	21	using	use	VERB
cana-431	81	22	optimization	optimization	NOUN
cana-431	81	23	algorithms	algorithm	NOUN
cana-431	81	24	.	.	PUNCT
cana-431	82	1	minimize	minimize	VERB
cana-431	82	2	:	:	PUNCT
cana-431	82	3	{	{	PUNCT
cana-431	82	4	f1(x	f1(x	NOUN
cana-431	82	5	,	,	PUNCT
cana-431	82	6	y	y	PROPN
cana-431	82	7	,	,	PUNCT
cana-431	82	8	z	z	NOUN
cana-431	82	9	)	)	PUNCT
cana-431	82	10	,	,	PUNCT
cana-431	82	11	f2	f2	PROPN
cana-431	82	12	(	(	PUNCT
cana-431	82	13	x	x	X
cana-431	82	14	,	,	PUNCT
cana-431	82	15	y	y	PROPN
cana-431	82	16	,	,	PUNCT
cana-431	82	17	z	z	NOUN
cana-431	82	18	)	)	PUNCT
cana-431	82	19	,	,	PUNCT
cana-431	82	20	f3(x	f3(x	PROPN
cana-431	82	21	,	,	PUNCT
cana-431	82	22	y	y	PROPN
cana-431	82	23	,	,	PUNCT
cana-431	82	24	z	z	NOUN
cana-431	82	25	)	)	PUNCT
cana-431	82	26	,	,	PUNCT
cana-431	82	27	f4(x	f4(x	PROPN
cana-431	82	28	,	,	PUNCT
cana-431	82	29	y	y	PROPN
cana-431	82	30	,	,	PUNCT
cana-431	82	31	z	z	NOUN
cana-431	82	32	)	)	PUNCT
cana-431	82	33	,	,	PUNCT
cana-431	82	34	f5(x	f5(x	PROPN
cana-431	82	35	,	,	PUNCT
cana-431	82	36	y	y	PROPN
cana-431	82	37	,	,	PUNCT
cana-431	82	38	z	z	NOUN
cana-431	82	39	)	)	PUNCT
cana-431	82	40	}	}	PUNCT
cana-431	82	41	insulin	insulin	NOUN
cana-431	82	42	dosage	dosage	NOUN
cana-431	82	43	:	:	PUNCT
cana-431	83	1	g	g	PROPN
cana-431	83	2	(	(	PUNCT
cana-431	83	3	t	t	PROPN
cana-431	83	4	):	):	PUNCT
cana-431	83	5	concentration	concentration	NOUN
cana-431	83	6	of	of	ADP
cana-431	83	7	plasma	plasma	NOUN
cana-431	83	8	at	at	ADP
cana-431	83	9	time	time	NOUN
cana-431	83	10	t.	t.	PROPN
cana-431	83	11	x(t	x(t	PROPN
cana-431	83	12	):	):	PUNCT
cana-431	83	13	action	action	NOUN
cana-431	83	14	of	of	ADP
cana-431	83	15	the	the	DET
cana-431	83	16	insulin	insulin	NOUN
cana-431	83	17	at	at	ADP
cana-431	83	18	time	time	NOUN
cana-431	83	19	t.	t.	PROPN
cana-431	83	20	gb	gb	NOUN
cana-431	83	21	:	:	PUNCT
cana-431	83	22	glucose	glucose	NOUN
cana-431	83	23	concentration	concentration	NOUN
cana-431	83	24	rate	rate	NOUN
cana-431	83	25	of	of	ADP
cana-431	83	26	change	change	NOUN
cana-431	83	27	of	of	ADP
cana-431	83	28	glucose	glucose	NOUN
cana-431	83	29	concentration	concentration	NOUN
cana-431	83	30	𝑑𝐺(𝑡	𝑑𝐺(𝑡	NOUN
cana-431	83	31	)	)	PUNCT
cana-431	83	32	𝑑𝑡	𝑑𝑡	ADP
cana-431	83	33	=	=	PUNCT
cana-431	83	34	−p1⋅[g(t)−gb	−p1⋅[g(t)−gb	X
cana-431	83	35	]	]	X
cana-431	83	36	−x(t)⋅g(t	−x(t)⋅g(t	NOUN
cana-431	83	37	)	)	PUNCT
cana-431	84	1	this	this	DET
cana-431	84	2	equation	equation	NOUN
cana-431	84	3	describes	describe	VERB
cana-431	84	4	the	the	DET
cana-431	84	5	rate	rate	NOUN
cana-431	84	6	of	of	ADP
cana-431	84	7	change	change	NOUN
cana-431	84	8	of	of	ADP
cana-431	84	9	glucose	glucose	NOUN
cana-431	84	10	levels	level	NOUN
cana-431	84	11	with	with	ADP
cana-431	84	12	respect	respect	NOUN
cana-431	84	13	to	to	ADP
cana-431	84	14	time	time	NOUN
cana-431	84	15	t.	t.	PROPN
cana-431	84	16	p1	p1	PROPN
cana-431	84	17	represents	represent	VERB
cana-431	84	18	the	the	DET
cana-431	84	19	rate	rate	NOUN
cana-431	84	20	of	of	ADP
cana-431	84	21	glucose	glucose	NOUN
cana-431	84	22	disappearance	disappearance	NOUN
cana-431	84	23	,	,	PUNCT
cana-431	84	24	gb	gb	PRON
cana-431	84	25	is	be	AUX
cana-431	84	26	the	the	DET
cana-431	84	27	basal	basal	ADJ
cana-431	84	28	glucose	glucose	NOUN
cana-431	84	29	concentration	concentration	NOUN
cana-431	84	30	,	,	PUNCT
cana-431	84	31	and	and	CCONJ
cana-431	84	32	x(t	x(t	PROPN
cana-431	84	33	)	)	PUNCT
cana-431	84	34	represents	represent	VERB
cana-431	84	35	action	action	NOUN
cana-431	84	36	of	of	ADP
cana-431	84	37	the	the	DET
cana-431	84	38	insulin	insulin	NOUN
cana-431	84	39	at	at	ADP
cana-431	84	40	time	time	NOUN
cana-431	84	41	t.	t.	NOUN
cana-431	84	42	concentration	concentration	NOUN
cana-431	84	43	of	of	ADP
cana-431	84	44	the	the	DET
cana-431	84	45	glucose	glucose	NOUN
cana-431	84	46	is	be	AUX
cana-431	84	47	totally	totally	ADV
cana-431	84	48	depending	depend	VERB
cana-431	84	49	on	on	ADP
cana-431	84	50	the	the	DET
cana-431	84	51	secretion	secretion	NOUN
cana-431	84	52	of	of	ADP
cana-431	84	53	insulin	insulin	NOUN
cana-431	84	54	.	.	PUNCT
cana-431	85	1	minus	minus	PROPN
cana-431	85	2	sign	sign	NOUN
cana-431	85	3	is	be	AUX
cana-431	85	4	used	use	VERB
cana-431	85	5	as	as	ADP
cana-431	85	6	to	to	PART
cana-431	85	7	minimize	minimize	VERB
cana-431	85	8	the	the	DET
cana-431	85	9	glucose	glucose	NOUN
cana-431	85	10	concentration	concentration	NOUN
cana-431	85	11	in	in	ADP
cana-431	85	12	the	the	DET
cana-431	85	13	plasma	plasma	NOUN
cana-431	85	14	.	.	PUNCT
cana-431	86	1	rate	rate	NOUN
cana-431	86	2	of	of	ADP
cana-431	86	3	change	change	NOUN
cana-431	86	4	of	of	ADP
cana-431	86	5	insulin	insulin	NOUN
cana-431	86	6	decay	decay	NOUN
cana-431	86	7	𝑑𝑋(𝑡	𝑑𝑋(𝑡	NOUN
cana-431	86	8	)	)	PUNCT
cana-431	86	9	𝑑𝑡	𝑑𝑡	ADP
cana-431	86	10	=	=	PUNCT
cana-431	86	11	−p2⋅	−p2⋅	PROPN
cana-431	86	12	x(t	x(t	PROPN
cana-431	86	13	)	)	PUNCT
cana-431	87	1	+	+	CCONJ
cana-431	87	2	p3⋅[i(t)−ib	p3⋅[i(t)−ib	ADP
cana-431	87	3	]	]	X
cana-431	87	4	communications	communication	NOUN
cana-431	87	5	on	on	ADP
cana-431	87	6	applied	apply	VERB
cana-431	87	7	nonlinear	nonlinear	ADJ
cana-431	87	8	analysis	analysis	NOUN
cana-431	87	9	issn	issn	NOUN
cana-431	87	10	:	:	PUNCT
cana-431	87	11	1074	1074	NUM
cana-431	87	12	-	-	PUNCT
cana-431	87	13	133x	133x	NUM
cana-431	87	14	vol	vol	NOUN
cana-431	87	15	31	31	NUM
cana-431	87	16	no	no	NOUN
cana-431	87	17	.	.	NOUN
cana-431	87	18	1	1	NUM
cana-431	87	19	(	(	PUNCT
cana-431	87	20	2024	2024	NUM
cana-431	87	21	)	)	PUNCT
cana-431	87	22	291	291	NUM
cana-431	87	23	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	87	24	this	this	DET
cana-431	87	25	derivative	derivative	NOUN
cana-431	87	26	describes	describe	VERB
cana-431	87	27	change	change	NOUN
cana-431	87	28	of	of	ADP
cana-431	87	29	insulin	insulin	NOUN
cana-431	87	30	action	action	NOUN
cana-431	87	31	with	with	ADP
cana-431	87	32	respect	respect	NOUN
cana-431	87	33	to	to	ADP
cana-431	87	34	time	time	NOUN
cana-431	87	35	.	.	PUNCT
cana-431	88	1	p2	p2	PROPN
cana-431	88	2	represents	represent	VERB
cana-431	88	3	the	the	DET
cana-431	88	4	rate	rate	NOUN
cana-431	88	5	of	of	ADP
cana-431	88	6	insulin	insulin	NOUN
cana-431	88	7	action	action	NOUN
cana-431	88	8	decay	decay	NOUN
cana-431	88	9	,	,	PUNCT
cana-431	88	10	ib	ib	NOUN
cana-431	88	11	represents	represent	VERB
cana-431	88	12	the	the	DET
cana-431	88	13	basal	basal	ADJ
cana-431	88	14	insulin	insulin	NOUN
cana-431	88	15	concentration	concentration	NOUN
cana-431	88	16	.	.	PUNCT
cana-431	89	1	where	where	SCONJ
cana-431	89	2	i(t	i(t	NOUN
cana-431	89	3	)	)	PUNCT
cana-431	89	4	represent	represent	VERB
cana-431	89	5	concentration	concentration	NOUN
cana-431	89	6	of	of	ADP
cana-431	89	7	the	the	DET
cana-431	89	8	insulin	insulin	NOUN
cana-431	89	9	at	at	ADP
cana-431	89	10	time	time	NOUN
cana-431	89	11	.	.	PUNCT
cana-431	90	1	insulin	insulin	NOUN
cana-431	90	2	secretion	secretion	NOUN
cana-431	90	3	:	:	PUNCT
cana-431	90	4	i(t)=s(t)⋅(g(t)−gb	i(t)=s(t)⋅(g(t)−gb	NUM
cana-431	90	5	)	)	PUNCT
cana-431	90	6	this	this	DET
cana-431	90	7	equation	equation	NOUN
cana-431	90	8	represents	represent	VERB
cana-431	90	9	a	a	DET
cana-431	90	10	simple	simple	ADJ
cana-431	90	11	model	model	NOUN
cana-431	90	12	of	of	ADP
cana-431	90	13	insulin	insulin	NOUN
cana-431	90	14	secretion	secretion	NOUN
cana-431	90	15	s(t	s(t	PROPN
cana-431	90	16	)	)	PUNCT
cana-431	90	17	,	,	PUNCT
cana-431	90	18	based	base	VERB
cana-431	90	19	on	on	ADP
cana-431	90	20	the	the	DET
cana-431	90	21	difference	difference	NOUN
cana-431	90	22	between	between	ADP
cana-431	90	23	actual	actual	ADJ
cana-431	90	24	and	and	CCONJ
cana-431	90	25	basal	basal	VERB
cana-431	90	26	glucose	glucose	NOUN
cana-431	90	27	levels	level	NOUN
cana-431	90	28	.	.	PUNCT
cana-431	91	1	it	it	PRON
cana-431	91	2	's	be	AUX
cana-431	91	3	necessary	necessary	ADJ
cana-431	91	4	to	to	PART
cana-431	91	5	keep	keep	VERB
cana-431	91	6	in	in	ADP
cana-431	91	7	mind	mind	NOUN
cana-431	91	8	that	that	SCONJ
cana-431	91	9	the	the	DET
cana-431	91	10	frequency	frequency	NOUN
cana-431	91	11	and	and	CCONJ
cana-431	91	12	severity	severity	NOUN
cana-431	91	13	of	of	ADP
cana-431	91	14	side	side	NOUN
cana-431	91	15	effects	effect	NOUN
cana-431	91	16	can	can	AUX
cana-431	91	17	vary	vary	VERB
cana-431	91	18	from	from	ADP
cana-431	91	19	person	person	NOUN
cana-431	91	20	to	to	ADP
cana-431	91	21	person	person	NOUN
cana-431	91	22	,	,	PUNCT
cana-431	91	23	and	and	CCONJ
cana-431	91	24	that	that	SCONJ
cana-431	91	25	managing	manage	VERB
cana-431	91	26	diabetes	diabete	NOUN
cana-431	91	27	well	well	ADV
cana-431	91	28	can	can	AUX
cana-431	91	29	reduce	reduce	VERB
cana-431	91	30	these	these	DET
cana-431	91	31	risks	risk	NOUN
cana-431	91	32	.	.	PUNCT
cana-431	92	1	here	here	ADV
cana-431	92	2	are	be	AUX
cana-431	92	3	some	some	DET
cana-431	92	4	common	common	ADJ
cana-431	92	5	side	side	NOUN
cana-431	92	6	effects	effect	NOUN
cana-431	92	7	and	and	CCONJ
cana-431	92	8	complications	complication	NOUN
cana-431	92	9	associated	associate	VERB
cana-431	92	10	with	with	ADP
cana-431	92	11	diabetes	diabetes	NOUN
cana-431	92	12	:	:	PUNCT
cana-431	92	13	general	general	ADJ
cana-431	92	14	diabetes	diabetes	NOUN
cana-431	92	15	model	model	NOUN
cana-431	92	16	:	:	PUNCT
cana-431	92	17	diabetes	diabetes	NOUN
cana-431	92	18	may	may	AUX
cana-431	92	19	consider	consider	VERB
cana-431	92	20	as	as	ADP
cana-431	92	21	slow	slow	ADJ
cana-431	92	22	poisoned	poison	VERB
cana-431	92	23	diseases	disease	NOUN
cana-431	92	24	which	which	PRON
cana-431	92	25	destroys	destroy	VERB
cana-431	92	26	the	the	DET
cana-431	92	27	working	work	VERB
cana-431	92	28	ability	ability	NOUN
cana-431	92	29	of	of	ADP
cana-431	92	30	the	the	DET
cana-431	92	31	important	important	ADJ
cana-431	92	32	organs	organ	NOUN
cana-431	92	33	and	and	CCONJ
cana-431	92	34	always	always	ADV
cana-431	92	35	effect	effect	VERB
cana-431	92	36	on	on	ADP
cana-431	92	37	how	how	SCONJ
cana-431	92	38	the	the	DET
cana-431	92	39	body	body	NOUN
cana-431	92	40	uses	use	VERB
cana-431	92	41	the	the	DET
cana-431	92	42	blood	blood	NOUN
cana-431	92	43	glucose	glucose	NOUN
cana-431	92	44	diabetes	diabetes	NOUN
cana-431	92	45	which	which	PRON
cana-431	92	46	is	be	AUX
cana-431	92	47	uncontrolled	uncontrolled	ADJ
cana-431	92	48	can	can	AUX
cana-431	92	49	lead	lead	VERB
cana-431	92	50	to	to	ADP
cana-431	92	51	various	various	ADJ
cana-431	92	52	complications	complication	NOUN
cana-431	92	53	hyperglyxemia	hyperglyxemia	NOUN
cana-431	92	54	,	,	PUNCT
cana-431	92	55	hypoglyxemia	hypoglyxemia	ADJ
cana-431	92	56	,	,	PUNCT
cana-431	92	57	cardiovascular	cardiovascular	ADJ
cana-431	92	58	complications	complication	NOUN
cana-431	92	59	,	,	PUNCT
cana-431	92	60	neuropathy	neuropathy	ADJ
cana-431	92	61	,	,	PUNCT
cana-431	92	62	nephropathy	nephropathy	ADJ
cana-431	92	63	,	,	PUNCT
cana-431	92	64	retinopathy	retinopathy	ADJ
cana-431	92	65	,	,	PUNCT
cana-431	92	66	skin	skin	NOUN
cana-431	92	67	complications	complication	NOUN
cana-431	92	68	gastroparesis	gastroparesis	NOUN
cana-431	92	69	,	,	PUNCT
cana-431	92	70	complications	complication	NOUN
cana-431	92	71	in	in	ADP
cana-431	92	72	pregnancy	pregnancy	NOUN
cana-431	92	73	.	.	PUNCT
cana-431	93	1	sometimes	sometimes	ADV
cana-431	93	2	these	these	DET
cana-431	93	3	kind	kind	NOUN
cana-431	93	4	of	of	ADP
cana-431	93	5	diseases	disease	NOUN
cana-431	93	6	leads	lead	VERB
cana-431	93	7	to	to	ADP
cana-431	93	8	the	the	DET
cana-431	93	9	death	death	NOUN
cana-431	93	10	.	.	PUNCT
cana-431	94	1	creating	create	VERB
cana-431	94	2	a	a	DET
cana-431	94	3	mathematical	mathematical	ADJ
cana-431	94	4	model	model	NOUN
cana-431	94	5	that	that	PRON
cana-431	94	6	encompasses	encompass	VERB
cana-431	94	7	all	all	DET
cana-431	94	8	the	the	DET
cana-431	94	9	mentioned	mention	VERB
cana-431	94	10	complications	complication	NOUN
cana-431	94	11	of	of	ADP
cana-431	94	12	diabetes	diabetes	NOUN
cana-431	94	13	involves	involve	VERB
cana-431	94	14	a	a	DET
cana-431	94	15	complex	complex	ADJ
cana-431	94	16	system	system	NOUN
cana-431	94	17	of	of	ADP
cana-431	94	18	equations	equation	NOUN
cana-431	94	19	and	and	CCONJ
cana-431	94	20	parameters	parameter	NOUN
cana-431	94	21	[	[	X
cana-431	94	22	14	14	NUM
cana-431	94	23	]	]	PUNCT
cana-431	94	24	.	.	PUNCT
cana-431	95	1	developing	develop	VERB
cana-431	95	2	a	a	DET
cana-431	95	3	comprehensive	comprehensive	ADJ
cana-431	95	4	model	model	NOUN
cana-431	95	5	requires	require	VERB
cana-431	95	6	consideration	consideration	NOUN
cana-431	95	7	of	of	ADP
cana-431	95	8	various	various	ADJ
cana-431	95	9	physiological	physiological	ADJ
cana-431	95	10	processes	process	NOUN
cana-431	95	11	,	,	PUNCT
cana-431	95	12	interactions	interaction	NOUN
cana-431	95	13	,	,	PUNCT
cana-431	95	14	and	and	CCONJ
cana-431	95	15	feedback	feedback	NOUN
cana-431	95	16	mechanisms	mechanism	NOUN
cana-431	95	17	.	.	PUNCT
cana-431	96	1	the	the	DET
cana-431	96	2	model	model	NOUN
cana-431	96	3	simulates	simulate	VERB
cana-431	96	4	the	the	DET
cana-431	96	5	dynamic	dynamic	ADJ
cana-431	96	6	interaction	interaction	NOUN
cana-431	96	7	between	between	ADP
cana-431	96	8	glucose	glucose	NOUN
cana-431	96	9	and	and	CCONJ
cana-431	96	10	insulin	insulin	NOUN
cana-431	96	11	,	,	PUNCT
cana-431	96	12	considering	consider	VERB
cana-431	96	13	glucose	glucose	NOUN
cana-431	96	14	production	production	NOUN
cana-431	96	15	utilization	utilization	NOUN
cana-431	96	16	,	,	PUNCT
cana-431	96	17	and	and	CCONJ
cana-431	96	18	insulin	insulin	NOUN
cana-431	96	19	action	action	NOUN
cana-431	96	20	.	.	PUNCT
cana-431	97	1	insulin	insulin	NOUN
cana-431	97	2	action	action	NOUN
cana-431	97	3	is	be	AUX
cana-431	97	4	influenced	influence	VERB
cana-431	97	5	by	by	ADP
cana-431	97	6	both	both	CCONJ
cana-431	97	7	the	the	DET
cana-431	97	8	insulin	insulin	NOUN
cana-431	97	9	concentration	concentration	NOUN
cana-431	97	10	and	and	CCONJ
cana-431	97	11	its	its	PRON
cana-431	97	12	decay	decay	NOUN
cana-431	97	13	rate	rate	NOUN
cana-431	97	14	.	.	PUNCT
cana-431	98	1	the	the	DET
cana-431	98	2	model	model	NOUN
cana-431	98	3	can	can	AUX
cana-431	98	4	be	be	AUX
cana-431	98	5	extended	extend	VERB
cana-431	98	6	to	to	PART
cana-431	98	7	include	include	VERB
cana-431	98	8	meal	meal	NOUN
cana-431	98	9	intake	intake	NOUN
cana-431	98	10	,	,	PUNCT
cana-431	98	11	physical	physical	ADJ
cana-431	98	12	activity	activity	NOUN
cana-431	98	13	,	,	PUNCT
cana-431	98	14	and	and	CCONJ
cana-431	98	15	more	more	ADV
cana-431	98	16	sophisticated	sophisticated	ADJ
cana-431	98	17	representations	representation	NOUN
cana-431	98	18	of	of	ADP
cana-431	98	19	insulin	insulin	NOUN
cana-431	98	20	secretion	secretion	NOUN
cana-431	98	21	.	.	PUNCT
cana-431	99	1	minimize	minimize	VERB
cana-431	99	2	{	{	PUNCT
cana-431	99	3	𝒇(𝒙	𝒇(𝒙	NOUN
cana-431	99	4	)	)	PUNCT
cana-431	99	5	}	}	PUNCT
cana-431	99	6	{	{	PUNCT
cana-431	99	7	(	(	PUNCT
cana-431	99	8	g(t	g(t	PROPN
cana-431	99	9	)	)	PUNCT
cana-431	99	10	,	,	PUNCT
cana-431	99	11	i(t	i(t	PROPN
cana-431	99	12	)	)	PUNCT
cana-431	99	13	,	,	PUNCT
cana-431	99	14	x(t	x(t	PROPN
cana-431	99	15	)	)	PUNCT
cana-431	99	16	,	,	PUNCT
cana-431	99	17	h(t	h(t	PROPN
cana-431	99	18	)	)	PUNCT
cana-431	99	19	,	,	PUNCT
cana-431	99	20	c(t	c(t	PROPN
cana-431	99	21	)	)	PUNCT
cana-431	99	22	,	,	PUNCT
cana-431	99	23	n(t	n(t	PROPN
cana-431	99	24	)	)	PUNCT
cana-431	99	25	,	,	PUNCT
cana-431	99	26	k(t	k(t	PROPN
cana-431	99	27	)	)	PUNCT
cana-431	99	28	,	,	PUNCT
cana-431	99	29	r(t	r(t	NOUN
cana-431	99	30	)	)	PUNCT
cana-431	99	31	,	,	PUNCT
cana-431	99	32	s(t	s(t	PROPN
cana-431	99	33	)	)	PUNCT
cana-431	99	34	,	,	PUNCT
cana-431	99	35	gp(t	gp(t	PROPN
cana-431	99	36	)	)	PUNCT
cana-431	99	37	,	,	PUNCT
cana-431	99	38	p(t	p(t	NOUN
cana-431	99	39	)	)	PUNCT
cana-431	99	40	}	}	PUNCT
cana-431	99	41	decision	decision	NOUN
cana-431	99	42	variable	variable	NOUN
cana-431	99	43	:	:	PUNCT
cana-431	100	1	g(t	g(t	PROPN
cana-431	100	2	):	):	PUNCT
cana-431	100	3	concentration	concentration	NOUN
cana-431	100	4	of	of	ADP
cana-431	100	5	plasma	plasma	NOUN
cana-431	100	6	glucose	glucose	NOUN
cana-431	100	7	at	at	ADP
cana-431	100	8	time	time	NOUN
cana-431	100	9	t.	t.	PROPN
cana-431	100	10	i(t	i(t	PROPN
cana-431	100	11	):	):	PUNCT
cana-431	100	12	concentration	concentration	NOUN
cana-431	100	13	of	of	ADP
cana-431	100	14	insulin	insulin	NOUN
cana-431	100	15	at	at	ADP
cana-431	100	16	time	time	NOUN
cana-431	100	17	t.	t.	PROPN
cana-431	100	18	x(t	x(t	PROPN
cana-431	100	19	):	):	PUNCT
cana-431	100	20	action(effectiveness	action(effectiveness	PROPN
cana-431	100	21	)	)	PUNCT
cana-431	100	22	of	of	ADP
cana-431	100	23	the	the	DET
cana-431	100	24	insulin	insulin	NOUN
cana-431	100	25	at	at	ADP
cana-431	100	26	time	time	NOUN
cana-431	100	27	t.	t.	PROPN
cana-431	100	28	h(t	h(t	PROPN
cana-431	100	29	):	):	PUNCT
cana-431	100	30	plasma	plasma	NOUN
cana-431	100	31	glucagon	glucagon	NOUN
cana-431	100	32	concentration	concentration	NOUN
cana-431	100	33	at	at	ADP
cana-431	100	34	time	time	NOUN
cana-431	100	35	t.	t.	PROPN
cana-431	100	36	c(t	c(t	PROPN
cana-431	100	37	):	):	PUNCT
cana-431	100	38	cardiovascular	cardiovascular	ADJ
cana-431	100	39	health	health	NOUN
cana-431	100	40	metric	metric	NOUN
cana-431	100	41	.	.	PUNCT
cana-431	101	1	n(t	n(t	NOUN
cana-431	101	2	):	):	PUNCT
cana-431	101	3	neuropathy	neuropathy	ADJ
cana-431	101	4	index	index	NOUN
cana-431	101	5	.	.	PUNCT
cana-431	102	1	k(t	k(t	NOUN
cana-431	102	2	):	):	PUNCT
cana-431	102	3	kidney	kidney	PROPN
cana-431	102	4	function	function	PROPN
cana-431	102	5	index	index	NOUN
cana-431	102	6	.	.	PUNCT
cana-431	103	1	r(t	r(t	NOUN
cana-431	103	2	):	):	PUNCT
cana-431	103	3	retinopathy	retinopathy	ADJ
cana-431	103	4	index	index	NOUN
cana-431	103	5	.	.	PUNCT
cana-431	104	1	s(t	s(t	PROPN
cana-431	104	2	):	):	PUNCT
cana-431	104	3	skin	skin	NOUN
cana-431	104	4	health	health	NOUN
cana-431	104	5	metric	metric	NOUN
cana-431	104	6	.	.	PUNCT
cana-431	105	1	g	g	ADP
cana-431	105	2	p(t	p(t	NOUN
cana-431	105	3	):	):	PUNCT
cana-431	105	4	gastric	gastric	ADJ
cana-431	105	5	motility	motility	NOUN
cana-431	105	6	index	index	NOUN
cana-431	105	7	(	(	PUNCT
cana-431	105	8	for	for	ADP
cana-431	105	9	gastroparesis	gastroparesis	NOUN
cana-431	105	10	)	)	PUNCT
cana-431	105	11	.	.	PUNCT
cana-431	106	1	p(t	p(t	NOUN
cana-431	106	2	):	):	PUNCT
cana-431	106	3	pregnancy	pregnancy	NOUN
cana-431	106	4	-	-	PUNCT
cana-431	106	5	related	relate	VERB
cana-431	106	6	index	index	NOUN
cana-431	106	7	.	.	PUNCT
cana-431	107	1	communications	communication	NOUN
cana-431	107	2	on	on	ADP
cana-431	107	3	applied	apply	VERB
cana-431	107	4	nonlinear	nonlinear	ADJ
cana-431	107	5	analysis	analysis	NOUN
cana-431	107	6	issn	issn	NOUN
cana-431	107	7	:	:	PUNCT
cana-431	107	8	1074	1074	NUM
cana-431	107	9	-	-	PUNCT
cana-431	107	10	133x	133x	NUM
cana-431	107	11	vol	vol	NOUN
cana-431	107	12	31	31	NUM
cana-431	107	13	no	no	NOUN
cana-431	107	14	.	.	NOUN
cana-431	107	15	1	1	NUM
cana-431	107	16	(	(	PUNCT
cana-431	107	17	2024	2024	NUM
cana-431	107	18	)	)	PUNCT
cana-431	107	19	292	292	NUM
cana-431	107	20	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	107	21	rate	rate	NOUN
cana-431	107	22	of	of	ADP
cana-431	107	23	change	change	NOUN
cana-431	107	24	of	of	ADP
cana-431	107	25	concentration	concentration	NOUN
cana-431	107	26	of	of	ADP
cana-431	107	27	glucose	glucose	NOUN
cana-431	107	28	𝑑𝐺(𝑡	𝑑𝐺(𝑡	ADP
cana-431	107	29	)	)	PUNCT
cana-431	107	30	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	31	=	=	NOUN
cana-431	107	32	−p1⋅(g(t)−gb	−p1⋅(g(t)−gb	NOUN
cana-431	107	33	)	)	PUNCT
cana-431	107	34	−x(t)⋅g(t	−x(t)⋅g(t	NUM
cana-431	107	35	)	)	PUNCT
cana-431	107	36	rate	rate	NOUN
cana-431	107	37	of	of	ADP
cana-431	107	38	change	change	NOUN
cana-431	107	39	of	of	ADP
cana-431	107	40	insulin	insulin	NOUN
cana-431	107	41	decay	decay	NOUN
cana-431	107	42	𝑑𝐼(𝑡	𝑑𝐼(𝑡	PRON
cana-431	107	43	)	)	PUNCT
cana-431	107	44	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	45	=	=	NOUN
cana-431	107	46	s(t)⋅(g(t)−gb	s(t)⋅(g(t)−gb	ADJ
cana-431	107	47	)	)	PUNCT
cana-431	107	48	−p2⋅i(t	−p2⋅i(t	NOUN
cana-431	107	49	)	)	PUNCT
cana-431	107	50	rate	rate	NOUN
cana-431	107	51	of	of	ADP
cana-431	107	52	change	change	NOUN
cana-431	107	53	of	of	ADP
cana-431	107	54	action	action	NOUN
cana-431	107	55	of	of	ADP
cana-431	107	56	the	the	DET
cana-431	107	57	insulin	insulin	NOUN
cana-431	107	58	𝑑𝑋(𝑡	𝑑𝑋(𝑡	PROPN
cana-431	107	59	)	)	PUNCT
cana-431	107	60	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	61	=	=	NOUN
cana-431	107	62	−p3⋅x(t)+p4⋅i(t	−p3⋅x(t)+p4⋅i(t	NOUN
cana-431	107	63	)	)	PUNCT
cana-431	107	64	rate	rate	NOUN
cana-431	107	65	of	of	ADP
cana-431	107	66	hypoglycaemia	hypoglycaemia	NOUN
cana-431	107	67	risk	risk	VERB
cana-431	107	68	𝑑𝐻(𝑡	𝑑𝐻(𝑡	PROPN
cana-431	107	69	)	)	PUNCT
cana-431	107	70	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	71	=	=	NOUN
cana-431	107	72	p5⋅(g(t)−gb	p5⋅(g(t)−gb	NUM
cana-431	107	73	)	)	PUNCT
cana-431	107	74	−p6⋅i(t	−p6⋅i(t	NOUN
cana-431	107	75	)	)	PUNCT
cana-431	107	76	rate	rate	NOUN
cana-431	107	77	of	of	ADP
cana-431	107	78	cardiovascular	cardiovascular	ADJ
cana-431	107	79	risk	risk	NOUN
cana-431	107	80	𝑑𝐶(𝑡	𝑑𝐶(𝑡	NUM
cana-431	107	81	)	)	PUNCT
cana-431	107	82	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	83	=	=	PROPN
cana-431	107	84	p7⋅g(t)−p8⋅x(t)+p9⋅(i(t)−ib	p7⋅g(t)−p8⋅x(t)+p9⋅(i(t)−ib	NOUN
cana-431	107	85	)	)	PUNCT
cana-431	107	86	rate	rate	NOUN
cana-431	107	87	of	of	ADP
cana-431	107	88	neuropathy	neuropathy	ADJ
cana-431	107	89	risk	risk	NOUN
cana-431	107	90	𝑑𝑁(𝑡	𝑑𝑁(𝑡	NUM
cana-431	107	91	)	)	PUNCT
cana-431	107	92	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	93	=	=	NOUN
cana-431	107	94	p10⋅(g(t)−gb	p10⋅(g(t)−gb	ADJ
cana-431	107	95	)	)	PUNCT
cana-431	107	96	−p11⋅x(t	−p11⋅x(t	PROPN
cana-431	107	97	)	)	PUNCT
cana-431	107	98	rate	rate	NOUN
cana-431	107	99	of	of	ADP
cana-431	107	100	nephropathy	nephropathy	ADJ
cana-431	107	101	risk	risk	NOUN
cana-431	107	102	𝑑𝑃(𝑡	𝑑𝑃(𝑡	NUM
cana-431	107	103	)	)	PUNCT
cana-431	107	104	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	105	=	=	SYM
cana-431	107	106	p12⋅g(t)−p13⋅x(t)+p14⋅[i(t)−ib	p12⋅g(t)−p13⋅x(t)+p14⋅[i(t)−ib	NOUN
cana-431	107	107	]	]	X
cana-431	107	108	rate	rate	NOUN
cana-431	107	109	of	of	ADP
cana-431	107	110	retinopathy	retinopathy	ADJ
cana-431	107	111	risk	risk	NOUN
cana-431	107	112	𝑑𝑅(𝑡	𝑑𝑅(𝑡	NUM
cana-431	107	113	)	)	PUNCT
cana-431	107	114	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	115	=	=	PROPN
cana-431	107	116	p15⋅(g(t)−gb	p15⋅(g(t)−gb	PROPN
cana-431	107	117	)	)	PUNCT
cana-431	107	118	−p16⋅x(t	−p16⋅x(t	PROPN
cana-431	107	119	)	)	PUNCT
cana-431	107	120	rate	rate	NOUN
cana-431	107	121	of	of	ADP
cana-431	107	122	skin	skin	NOUN
cana-431	107	123	complication	complication	NOUN
cana-431	107	124	risk	risk	NOUN
cana-431	107	125	𝑑𝑆(𝑡	𝑑𝑆(𝑡	NOUN
cana-431	107	126	)	)	PUNCT
cana-431	107	127	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	128	=	=	PUNCT
cana-431	107	129	p17⋅g(t)+p18⋅x(t)−p19⋅i(t	p17⋅g(t)+p18⋅x(t)−p19⋅i(t	NOUN
cana-431	107	130	)	)	PUNCT
cana-431	107	131	rate	rate	NOUN
cana-431	107	132	of	of	ADP
cana-431	107	133	gastroparesis	gastroparesis	NOUN
cana-431	107	134	risk	risk	NOUN
cana-431	107	135	𝑑𝐺𝑝(𝑡	𝑑𝐺𝑝(𝑡	ADJ
cana-431	107	136	)	)	PUNCT
cana-431	107	137	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	138	=	=	NOUN
cana-431	107	139	p20⋅(g(t)−gb	p20⋅(g(t)−gb	NOUN
cana-431	107	140	)	)	PUNCT
cana-431	107	141	−p21⋅x(t	−p21⋅x(t	PROPN
cana-431	107	142	)	)	PUNCT
cana-431	107	143	rate	rate	NOUN
cana-431	107	144	of	of	ADP
cana-431	107	145	pregnancy	pregnancy	NOUN
cana-431	107	146	complications	complication	NOUN
cana-431	107	147	risk	risk	VERB
cana-431	107	148	𝑑𝑃𝑝(𝑡	𝑑𝑃𝑝(𝑡	PROPN
cana-431	107	149	)	)	PUNCT
cana-431	107	150	𝑑𝑡	𝑑𝑡	ADP
cana-431	107	151	=	=	NOUN
cana-431	107	152	p22⋅(g(t)−gb	p22⋅(g(t)−gb	NOUN
cana-431	107	153	)	)	PUNCT
cana-431	107	154	+	+	ADJ
cana-431	107	155	p23⋅x(t)−p24⋅i(t	p23⋅x(t)−p24⋅i(t	ADJ
cana-431	107	156	)	)	PUNCT
cana-431	107	157	parameters	parameter	NOUN
cana-431	107	158	:	:	PUNCT
cana-431	107	159	pi	pi	NOUN
cana-431	107	160	-parameters	-parameter	NOUN
cana-431	107	161	affecting	affect	VERB
cana-431	107	162	rate	rate	NOUN
cana-431	107	163	of	of	ADP
cana-431	107	164	glucose	glucose	NOUN
cana-431	107	165	,	,	PUNCT
cana-431	107	166	insulin	insulin	NOUN
cana-431	107	167	decay	decay	NOUN
cana-431	107	168	,	,	PUNCT
cana-431	107	169	changes	change	NOUN
cana-431	107	170	in	in	ADP
cana-431	107	171	insulin	insulin	NOUN
cana-431	107	172	concentration	concentration	NOUN
cana-431	107	173	and	and	CCONJ
cana-431	107	174	risks	risk	NOUN
cana-431	107	175	associated	associate	VERB
cana-431	107	176	with	with	ADP
cana-431	107	177	complications	complication	NOUN
cana-431	107	178	.	.	PUNCT
cana-431	108	1	pj	pj	PROPN
cana-431	108	2	-parameters	-parameter	NOUN
cana-431	108	3	used	use	VERB
cana-431	108	4	to	to	PART
cana-431	108	5	evaluate	evaluate	VERB
cana-431	108	6	skin	skin	NOUN
cana-431	108	7	health	health	NOUN
cana-431	108	8	,	,	PUNCT
cana-431	108	9	cardiovascular	cardiovascular	ADJ
cana-431	108	10	complications	complication	NOUN
cana-431	108	11	,	,	PUNCT
cana-431	108	12	neuropathy	neuropathy	ADJ
cana-431	108	13	,	,	PUNCT
cana-431	108	14	nephropathy	nephropathy	ADJ
cana-431	108	15	,	,	PUNCT
cana-431	108	16	retinopathy	retinopathy	ADJ
cana-431	108	17	,	,	PUNCT
cana-431	108	18	skin	skin	NOUN
cana-431	108	19	complications	complication	NOUN
cana-431	108	20	,	,	PUNCT
cana-431	108	21	gastroparesis	gastroparesis	NOUN
cana-431	108	22	,	,	PUNCT
cana-431	108	23	and	and	CCONJ
cana-431	108	24	complications	complication	NOUN
cana-431	108	25	in	in	ADP
cana-431	108	26	pregnancy	pregnancy	NOUN
cana-431	108	27	communications	communication	NOUN
cana-431	108	28	on	on	ADP
cana-431	108	29	applied	apply	VERB
cana-431	108	30	nonlinear	nonlinear	ADJ
cana-431	108	31	analysis	analysis	NOUN
cana-431	108	32	issn	issn	NOUN
cana-431	108	33	:	:	PUNCT
cana-431	108	34	1074	1074	NUM
cana-431	108	35	-	-	PUNCT
cana-431	108	36	133x	133x	NUM
cana-431	108	37	vol	vol	NOUN
cana-431	108	38	31	31	NUM
cana-431	108	39	no	no	NOUN
cana-431	108	40	.	.	NOUN
cana-431	108	41	1	1	NUM
cana-431	108	42	(	(	PUNCT
cana-431	108	43	2024	2024	NUM
cana-431	108	44	)	)	PUNCT
cana-431	108	45	293	293	NUM
cana-431	108	46	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	108	47	parameter	parameter	NOUN
cana-431	108	48	estimation	estimation	NOUN
cana-431	108	49	methods	method	NOUN
cana-431	108	50	:	:	PUNCT
cana-431	108	51	in	in	ADP
cana-431	108	52	the	the	DET
cana-431	108	53	context	context	NOUN
cana-431	108	54	of	of	ADP
cana-431	108	55	diabetes	diabetes	NOUN
cana-431	108	56	modelling	modelling	NOUN
cana-431	108	57	,	,	PUNCT
cana-431	108	58	both	both	DET
cana-431	108	59	least	least	ADJ
cana-431	108	60	squares	square	NOUN
cana-431	108	61	and	and	CCONJ
cana-431	108	62	maximum	maximum	ADJ
cana-431	108	63	likelihood	likelihood	NOUN
cana-431	108	64	methods	method	NOUN
cana-431	108	65	can	can	AUX
cana-431	108	66	be	be	AUX
cana-431	108	67	applied	apply	VERB
cana-431	108	68	,	,	PUNCT
cana-431	108	69	depending	depend	VERB
cana-431	108	70	on	on	ADP
cana-431	108	71	the	the	DET
cana-431	108	72	nature	nature	NOUN
cana-431	108	73	of	of	ADP
cana-431	108	74	the	the	DET
cana-431	108	75	data	datum	NOUN
cana-431	108	76	and	and	CCONJ
cana-431	108	77	the	the	DET
cana-431	108	78	specific	specific	ADJ
cana-431	108	79	goals	goal	NOUN
cana-431	108	80	of	of	ADP
cana-431	108	81	the	the	DET
cana-431	108	82	modelling	modelling	NOUN
cana-431	108	83	effort	effort	NOUN
cana-431	108	84	[	[	X
cana-431	108	85	15	15	NUM
cana-431	108	86	]	]	PUNCT
cana-431	108	87	.	.	PUNCT
cana-431	109	1	understanding	understanding	NOUN
cana-431	109	2	and	and	CCONJ
cana-431	109	3	managing	manage	VERB
cana-431	109	4	these	these	DET
cana-431	109	5	parameters	parameter	NOUN
cana-431	109	6	is	be	AUX
cana-431	109	7	essential	essential	ADJ
cana-431	109	8	for	for	ADP
cana-431	109	9	optimizing	optimize	VERB
cana-431	109	10	glucose	glucose	NOUN
cana-431	109	11	and	and	CCONJ
cana-431	109	12	insulin	insulin	NOUN
cana-431	109	13	regulation	regulation	NOUN
cana-431	109	14	and	and	CCONJ
cana-431	109	15	reducing	reduce	VERB
cana-431	109	16	the	the	DET
cana-431	109	17	risks	risk	NOUN
cana-431	109	18	associated	associate	VERB
cana-431	109	19	with	with	ADP
cana-431	109	20	diabetes	diabetes	NOUN
cana-431	109	21	complications	complication	NOUN
cana-431	109	22	.	.	PUNCT
cana-431	110	1	initial	initial	ADJ
cana-431	110	2	conditions	condition	NOUN
cana-431	110	3	:	:	PUNCT
cana-431	110	4	data	data	NOUN
cana-431	110	5	collection	collection	NOUN
cana-431	110	6	:	:	PUNCT
cana-431	110	7	data	datum	NOUN
cana-431	110	8	related	relate	VERB
cana-431	110	9	to	to	ADP
cana-431	110	10	the	the	DET
cana-431	110	11	diabetic	diabetic	ADJ
cana-431	110	12	patients	patient	NOUN
cana-431	110	13	both	both	CCONJ
cana-431	110	14	male	male	ADJ
cana-431	110	15	and	and	CCONJ
cana-431	110	16	female	female	ADJ
cana-431	110	17	of	of	ADP
cana-431	110	18	all	all	DET
cana-431	110	19	age	age	NOUN
cana-431	110	20	categories	category	NOUN
cana-431	110	21	was	be	AUX
cana-431	110	22	collected	collect	VERB
cana-431	110	23	.	.	PUNCT
cana-431	111	1	this	this	DET
cana-431	111	2	data	datum	NOUN
cana-431	111	3	included	include	VERB
cana-431	111	4	the	the	DET
cana-431	111	5	blood	blood	NOUN
cana-431	111	6	glucose	glucose	NOUN
cana-431	111	7	levels	level	NOUN
cana-431	111	8	,	,	PUNCT
cana-431	111	9	insulin	insulin	NOUN
cana-431	111	10	levels	level	NOUN
cana-431	111	11	,	,	PUNCT
cana-431	111	12	meal	meal	NOUN
cana-431	111	13	intake	intake	NOUN
cana-431	111	14	,	,	PUNCT
cana-431	111	15	physical	physical	ADJ
cana-431	111	16	activity	activity	NOUN
cana-431	111	17	,	,	PUNCT
cana-431	111	18	medicine	medicine	NOUN
cana-431	111	19	type	type	NOUN
cana-431	111	20	and	and	CCONJ
cana-431	111	21	other	other	ADJ
cana-431	111	22	relevant	relevant	ADJ
cana-431	111	23	variables	variable	NOUN
cana-431	111	24	.	.	PUNCT
cana-431	112	1	data	datum	NOUN
cana-431	112	2	collected	collect	VERB
cana-431	112	3	by	by	ADP
cana-431	112	4	creating	create	VERB
cana-431	112	5	a	a	DET
cana-431	112	6	google	google	NOUN
cana-431	112	7	form	form	NOUN
cana-431	112	8	distributed	distribute	VERB
cana-431	112	9	amongst	amongst	ADP
cana-431	112	10	diabetic	diabetic	ADJ
cana-431	112	11	patient	patient	NOUN
cana-431	112	12	of	of	ADP
cana-431	112	13	all	all	DET
cana-431	112	14	age	age	NOUN
cana-431	112	15	level	level	NOUN
cana-431	112	16	including	include	VERB
cana-431	112	17	both	both	CCONJ
cana-431	112	18	male	male	NOUN
cana-431	112	19	and	and	CCONJ
cana-431	112	20	females	female	NOUN
cana-431	112	21	.	.	PUNCT
cana-431	113	1	the	the	DET
cana-431	113	2	parameters	parameter	NOUN
cana-431	113	3	in	in	ADP
cana-431	113	4	model	model	NOUN
cana-431	113	5	that	that	PRON
cana-431	113	6	need	need	VERB
cana-431	113	7	to	to	PART
cana-431	113	8	be	be	AUX
cana-431	113	9	estimated	estimate	VERB
cana-431	113	10	could	could	AUX
cana-431	113	11	include	include	VERB
cana-431	113	12	parameters	parameter	NOUN
cana-431	113	13	related	relate	VERB
cana-431	113	14	to	to	ADP
cana-431	113	15	insulin	insulin	NOUN
cana-431	113	16	sensitivity	sensitivity	NOUN
cana-431	113	17	,	,	PUNCT
cana-431	113	18	beta	beta	NOUN
cana-431	113	19	-	-	PUNCT
cana-431	113	20	cell	cell	NOUN
cana-431	113	21	function	function	NOUN
cana-431	113	22	,	,	PUNCT
cana-431	113	23	glucose	glucose	NOUN
cana-431	113	24	clearance	clearance	NOUN
cana-431	113	25	rates	rate	NOUN
cana-431	113	26	,	,	PUNCT
cana-431	113	27	and	and	CCONJ
cana-431	113	28	other	other	ADJ
cana-431	113	29	factors	factor	NOUN
cana-431	113	30	.	.	PUNCT
cana-431	114	1	data	datum	NOUN
cana-431	114	2	included	include	VERB
cana-431	114	3	age	age	NOUN
cana-431	114	4	,	,	PUNCT
cana-431	114	5	weight	weight	VERB
cana-431	114	6	their	their	PRON
cana-431	114	7	physical	physical	ADJ
cana-431	114	8	activities	activity	NOUN
cana-431	114	9	,	,	PUNCT
cana-431	114	10	their	their	PRON
cana-431	114	11	diabetic	diabetic	ADJ
cana-431	114	12	type	type	NOUN
cana-431	114	13	,	,	PUNCT
cana-431	114	14	pre	pre	X
cana-431	114	15	meal	meal	NOUN
cana-431	114	16	and	and	CCONJ
cana-431	114	17	the	the	DET
cana-431	114	18	post	post	NOUN
cana-431	114	19	meal	meal	NOUN
cana-431	114	20	sugar	sugar	NOUN
cana-431	114	21	,	,	PUNCT
cana-431	114	22	the	the	DET
cana-431	114	23	kind	kind	NOUN
cana-431	114	24	of	of	ADP
cana-431	114	25	the	the	DET
cana-431	114	26	disease	disease	NOUN
cana-431	114	27	patients	patient	NOUN
cana-431	114	28	suffered	suffer	VERB
cana-431	114	29	after	after	ADP
cana-431	114	30	post	post	NOUN
cana-431	114	31	diabetics	diabetic	NOUN
cana-431	114	32	.	.	PUNCT
cana-431	115	1	the	the	DET
cana-431	115	2	kind	kind	NOUN
cana-431	115	3	of	of	ADP
cana-431	115	4	the	the	DET
cana-431	115	5	treatments	treatment	NOUN
cana-431	115	6	they	they	PRON
cana-431	115	7	included	include	VERB
cana-431	115	8	in	in	ADP
cana-431	115	9	their	their	PRON
cana-431	115	10	daily	daily	ADJ
cana-431	115	11	life	life	NOUN
cana-431	115	12	to	to	PART
cana-431	115	13	control	control	VERB
cana-431	115	14	the	the	DET
cana-431	115	15	glucose	glucose	NOUN
cana-431	115	16	levels	level	NOUN
cana-431	115	17	etc	etc	X
cana-431	115	18	.	.	X
cana-431	116	1	from	from	ADP
cana-431	116	2	the	the	DET
cana-431	116	3	collected	collect	VERB
cana-431	116	4	data	datum	NOUN
cana-431	116	5	it	it	PRON
cana-431	116	6	has	have	AUX
cana-431	116	7	been	be	AUX
cana-431	116	8	observed	observe	VERB
cana-431	116	9	that	that	SCONJ
cana-431	116	10	diabetes	diabetes	NOUN
cana-431	116	11	diseases	disease	NOUN
cana-431	116	12	occurred	occur	VERB
cana-431	116	13	more	more	ADV
cana-431	116	14	in	in	ADP
cana-431	116	15	male	male	NOUN
cana-431	116	16	as	as	SCONJ
cana-431	116	17	compare	compare	ADJ
cana-431	116	18	to	to	ADP
cana-431	116	19	the	the	DET
cana-431	116	20	women	woman	NOUN
cana-431	116	21	.	.	PUNCT
cana-431	117	1	generally	generally	ADV
cana-431	117	2	,	,	PUNCT
cana-431	117	3	women	woman	NOUN
cana-431	117	4	suffered	suffer	VERB
cana-431	117	5	from	from	ADP
cana-431	117	6	diabetes	diabetes	NOUN
cana-431	117	7	due	due	ADP
cana-431	117	8	to	to	ADP
cana-431	117	9	obesity	obesity	NOUN
cana-431	117	10	and	and	CCONJ
cana-431	117	11	post	post	VERB
cana-431	117	12	pregnancy	pregnancy	NOUN
cana-431	117	13	hormonal	hormonal	ADJ
cana-431	117	14	changes	change	NOUN
cana-431	117	15	.	.	PUNCT
cana-431	118	1	stress	stress	NOUN
cana-431	118	2	may	may	AUX
cana-431	118	3	be	be	AUX
cana-431	118	4	one	one	NUM
cana-431	118	5	of	of	ADP
cana-431	118	6	the	the	DET
cana-431	118	7	reasons	reason	NOUN
cana-431	118	8	to	to	PART
cana-431	118	9	occur	occur	VERB
cana-431	118	10	diabetes	diabetes	NOUN
cana-431	118	11	in	in	ADP
cana-431	118	12	the	the	DET
cana-431	118	13	females	female	NOUN
cana-431	118	14	[	[	X
cana-431	118	15	16	16	NUM
cana-431	118	16	]	]	PUNCT
cana-431	118	17	.	.	PUNCT
cana-431	119	1	tabulated	tabulate	VERB
cana-431	119	2	data	datum	NOUN
cana-431	119	3	is	be	AUX
cana-431	119	4	as	as	ADV
cana-431	119	5	follow	follow	VERB
cana-431	119	6	.	.	PUNCT
cana-431	120	1	1.1	1.1	NUM
cana-431	120	2	table	table	NOUN
cana-431	120	3	related	relate	VERB
cana-431	120	4	to	to	ADP
cana-431	120	5	diabetic	diabetic	ADJ
cana-431	120	6	male	male	ADJ
cana-431	120	7	and	and	CCONJ
cana-431	120	8	female	female	ADJ
cana-431	120	9	communications	communication	NOUN
cana-431	120	10	on	on	ADP
cana-431	120	11	applied	apply	VERB
cana-431	120	12	nonlinear	nonlinear	ADJ
cana-431	120	13	analysis	analysis	NOUN
cana-431	120	14	issn	issn	NOUN
cana-431	120	15	:	:	PUNCT
cana-431	120	16	1074	1074	NUM
cana-431	120	17	-	-	PUNCT
cana-431	120	18	133x	133x	NUM
cana-431	120	19	vol	vol	NOUN
cana-431	120	20	31	31	NUM
cana-431	120	21	no	no	NOUN
cana-431	120	22	.	.	NOUN
cana-431	120	23	1	1	NUM
cana-431	120	24	(	(	PUNCT
cana-431	120	25	2024	2024	NUM
cana-431	120	26	)	)	PUNCT
cana-431	120	27	294	294	NUM
cana-431	120	28	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	120	29	category	category	NOUN
cana-431	120	30	wise	wise	ADJ
cana-431	120	31	graphs	graph	NOUN
cana-431	120	32	are	be	AUX
cana-431	120	33	:	:	PUNCT
cana-431	120	34	collected	collect	VERB
cana-431	120	35	data	datum	NOUN
cana-431	120	36	distributed	distribute	VERB
cana-431	120	37	1.2	1.2	NUM
cana-431	120	38	female	female	ADJ
cana-431	120	39	diabetic	diabetic	NOUN
cana-431	120	40	graph	graph	NOUN
cana-431	120	41	1.3	1.3	NUM
cana-431	120	42	male	male	ADJ
cana-431	120	43	diabetic	diabetic	ADJ
cana-431	120	44	graph	graph	NOUN
cana-431	120	45	model	model	NOUN
cana-431	120	46	fitting	fitting	ADJ
cana-431	120	47	:	:	PUNCT
cana-431	120	48	apply	apply	VERB
cana-431	120	49	the	the	DET
cana-431	120	50	chosen	choose	VERB
cana-431	120	51	optimization	optimization	NOUN
cana-431	120	52	algorithm	algorithm	NOUN
cana-431	120	53	to	to	PART
cana-431	120	54	find	find	VERB
cana-431	120	55	the	the	DET
cana-431	120	56	values	value	NOUN
cana-431	120	57	of	of	ADP
cana-431	120	58	the	the	DET
cana-431	120	59	parameters	parameter	NOUN
cana-431	120	60	that	that	PRON
cana-431	120	61	minimize	minimize	VERB
cana-431	120	62	the	the	DET
cana-431	120	63	difference	difference	NOUN
cana-431	120	64	between	between	ADP
cana-431	120	65	model	model	NOUN
cana-431	120	66	predictions	prediction	NOUN
cana-431	120	67	and	and	CCONJ
cana-431	120	68	observed	observed	ADJ
cana-431	120	69	data	datum	NOUN
cana-431	120	70	.	.	PUNCT
cana-431	121	1	g	g	NOUN
cana-431	121	2	(	(	PUNCT
cana-431	121	3	0	0	NUM
cana-431	121	4	):	):	PUNCT
cana-431	121	5	initial	initial	ADJ
cana-431	121	6	plasma	plasma	NOUN
cana-431	121	7	glucose	glucose	NOUN
cana-431	121	8	concentration	concentration	NOUN
cana-431	121	9	at	at	ADP
cana-431	121	10	time	time	NOUN
cana-431	121	11	t=0	t=0	SCONJ
cana-431	121	12	i	i	PROPN
cana-431	121	13	(	(	PUNCT
cana-431	121	14	0	0	NUM
cana-431	121	15	):	):	PUNCT
cana-431	121	16	insulin	insulin	NOUN
cana-431	121	17	concentration	concentration	NOUN
cana-431	121	18	at	at	ADP
cana-431	121	19	time	time	NOUN
cana-431	121	20	t=0	t=0	X
cana-431	121	21	.	.	NOUN
cana-431	121	22	x	x	SYM
cana-431	121	23	(	(	PUNCT
cana-431	121	24	0	0	NUM
cana-431	121	25	):	):	PUNCT
cana-431	121	26	action	action	NOUN
cana-431	121	27	of	of	ADP
cana-431	121	28	the	the	DET
cana-431	121	29	insulin	insulin	NOUN
cana-431	121	30	at	at	ADP
cana-431	121	31	time	time	NOUN
cana-431	121	32	t.	t.	PROPN
cana-431	121	33	h	h	PROPN
cana-431	121	34	(	(	PUNCT
cana-431	121	35	0	0	NUM
cana-431	121	36	):	):	PUNCT
cana-431	121	37	concentration	concentration	NOUN
cana-431	121	38	of	of	ADP
cana-431	121	39	the	the	DET
cana-431	121	40	plasma	plasma	NOUN
cana-431	121	41	glucagon	glucagon	NOUN
cana-431	121	42	at	at	ADP
cana-431	121	43	time	time	NOUN
cana-431	121	44	t=0	t=0	PROPN
cana-431	121	45	.	.	PUNCT
cana-431	122	1	c	c	PROPN
cana-431	122	2	(	(	PUNCT
cana-431	122	3	0	0	NUM
cana-431	122	4	):	):	PUNCT
cana-431	122	5	cardiovascular	cardiovascular	ADJ
cana-431	122	6	health	health	NOUN
cana-431	122	7	metric	metric	NOUN
cana-431	122	8	at	at	ADP
cana-431	122	9	time	time	NOUN
cana-431	122	10	t	t	PROPN
cana-431	122	11	=	=	NOUN
cana-431	122	12	0	0	PROPN
cana-431	122	13	.	.	PUNCT
cana-431	123	1	n	n	PROPN
cana-431	123	2	(	(	PUNCT
cana-431	123	3	0	0	NUM
cana-431	123	4	):	):	PUNCT
cana-431	123	5	neuropathy	neuropathy	ADJ
cana-431	123	6	index	index	NOUN
cana-431	123	7	at	at	ADP
cana-431	123	8	time	time	NOUN
cana-431	123	9	t=0	t=0	X
cana-431	123	10	.	.	PUNCT
cana-431	124	1	k(0	k(0	PROPN
cana-431	124	2	):	):	PUNCT
cana-431	124	3	kidney	kidney	NOUN
cana-431	124	4	function	function	NOUN
cana-431	124	5	index	index	NOUN
cana-431	124	6	at	at	ADP
cana-431	124	7	time	time	NOUN
cana-431	124	8	t=0	t=0	PROPN
cana-431	124	9	.	.	PUNCT
cana-431	125	1	r(0	r(0	PROPN
cana-431	125	2	):	):	PUNCT
cana-431	125	3	retinopathy	retinopathy	ADJ
cana-431	125	4	index	index	NOUN
cana-431	125	5	at	at	ADP
cana-431	125	6	time	time	NOUN
cana-431	125	7	t=0	t=0	X
cana-431	125	8	0	0	NUM
cana-431	125	9	100	100	NUM
cana-431	125	10	200	200	NUM
cana-431	125	11	300	300	NUM
cana-431	125	12	400	400	NUM
cana-431	125	13	500	500	NUM
cana-431	125	14	600	600	NUM
cana-431	125	15	1	1	NUM
cana-431	125	16	2	2	NUM
cana-431	125	17	3	3	NUM
cana-431	125	18	4	4	NUM
cana-431	125	19	5	5	NUM
cana-431	125	20	6	6	NUM
cana-431	125	21	7	7	NUM
cana-431	125	22	8	8	NUM
cana-431	125	23	9	9	NUM
cana-431	125	24	10	10	NUM
cana-431	125	25	11	11	NUM
cana-431	125	26	female	female	ADJ
cana-431	125	27	diabetic	diabetic	NOUN
cana-431	125	28	graph	graph	NOUN
cana-431	125	29	age	age	NOUN
cana-431	125	30	weight	weight	NOUN
cana-431	125	31	blood	blood	NOUN
cana-431	125	32	group	group	NOUN
cana-431	125	33	type	type	NOUN
cana-431	125	34	diabetic	diabetic	ADJ
cana-431	125	35	type	type	NOUN
cana-431	125	36	glucose	glucose	NOUN
cana-431	125	37	level	level	NOUN
cana-431	125	38	fasting	fast	VERB
cana-431	125	39	glucose	glucose	NOUN
cana-431	125	40	level	level	NOUN
cana-431	125	41	post	post	NOUN
cana-431	125	42	meal	meal	NOUN
cana-431	125	43	0	0	NUM
cana-431	125	44	100	100	NUM
cana-431	125	45	200	200	NUM
cana-431	125	46	300	300	NUM
cana-431	125	47	400	400	NUM
cana-431	125	48	500	500	NUM
cana-431	125	49	600	600	NUM
cana-431	125	50	1	1	NUM
cana-431	125	51	2	2	NUM
cana-431	125	52	3	3	NUM
cana-431	125	53	4	4	NUM
cana-431	125	54	5	5	NUM
cana-431	125	55	6	6	NUM
cana-431	125	56	7	7	NUM
cana-431	125	57	8	8	NUM
cana-431	125	58	9	9	NUM
cana-431	125	59	10	10	NUM
cana-431	125	60	11	11	NUM
cana-431	125	61	12	12	NUM
cana-431	125	62	13	13	NUM
cana-431	125	63	14	14	NUM
cana-431	125	64	male	male	ADJ
cana-431	125	65	diabetic	diabetic	ADJ
cana-431	125	66	graph	graph	NOUN
cana-431	125	67	age	age	NOUN
cana-431	125	68	weight	weight	NOUN
cana-431	125	69	blood	blood	NOUN
cana-431	125	70	group	group	NOUN
cana-431	125	71	type	type	NOUN
cana-431	125	72	diabetic	diabetic	ADJ
cana-431	125	73	type	type	NOUN
cana-431	125	74	glucose	glucose	NOUN
cana-431	125	75	level	level	NOUN
cana-431	125	76	fasting	fast	VERB
cana-431	125	77	glucose	glucose	NOUN
cana-431	125	78	level	level	NOUN
cana-431	125	79	post	post	NOUN
cana-431	125	80	meal	meal	NOUN
cana-431	125	81	communications	communication	NOUN
cana-431	125	82	on	on	ADP
cana-431	125	83	applied	apply	VERB
cana-431	125	84	nonlinear	nonlinear	ADJ
cana-431	125	85	analysis	analysis	NOUN
cana-431	125	86	issn	issn	NOUN
cana-431	125	87	:	:	PUNCT
cana-431	125	88	1074	1074	NUM
cana-431	125	89	-	-	PUNCT
cana-431	125	90	133x	133x	NUM
cana-431	125	91	vol	vol	NOUN
cana-431	125	92	31	31	NUM
cana-431	125	93	no	no	NOUN
cana-431	125	94	.	.	NOUN
cana-431	125	95	1	1	NUM
cana-431	125	96	(	(	PUNCT
cana-431	125	97	2024	2024	NUM
cana-431	125	98	)	)	PUNCT
cana-431	125	99	295	295	NUM
cana-431	126	1	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	126	2	s(0	s(0	PROPN
cana-431	126	3	):	):	PUNCT
cana-431	126	4	skin	skin	NOUN
cana-431	126	5	health	health	NOUN
cana-431	126	6	metric	metric	NOUN
cana-431	126	7	at	at	ADP
cana-431	126	8	time	time	NOUN
cana-431	126	9	t=0	t=0	X
cana-431	126	10	.	.	PUNCT
cana-431	127	1	gp(0	gp(0	NOUN
cana-431	127	2	):	):	PUNCT
cana-431	127	3	gastric	gastric	ADJ
cana-431	127	4	motility	motility	NOUN
cana-431	127	5	index	index	NOUN
cana-431	127	6	(	(	PUNCT
cana-431	127	7	for	for	ADP
cana-431	127	8	gastroparesis	gastroparesis	NOUN
cana-431	127	9	)	)	PUNCT
cana-431	127	10	at	at	ADP
cana-431	127	11	time	time	NOUN
cana-431	127	12	t=0	t=0	X
cana-431	127	13	.	.	PUNCT
cana-431	128	1	p	p	X
cana-431	128	2	(	(	PUNCT
cana-431	128	3	0	0	NUM
cana-431	128	4	):	):	PUNCT
cana-431	128	5	pregnancy	pregnancy	NOUN
cana-431	128	6	-	-	PUNCT
cana-431	128	7	related	relate	VERB
cana-431	128	8	index	index	NOUN
cana-431	128	9	at	at	ADP
cana-431	128	10	time	time	NOUN
cana-431	128	11	t=0	t=0	PROPN
cana-431	128	12	.	.	PUNCT
cana-431	128	13	calculations	calculation	NOUN
cana-431	128	14	:	:	PUNCT
cana-431	128	15	by	by	ADP
cana-431	128	16	using	use	VERB
cana-431	128	17	values	value	NOUN
cana-431	128	18	in	in	ADP
cana-431	128	19	table	table	NOUN
cana-431	128	20	1.1	1.1	NUM
cana-431	128	21	and	and	CCONJ
cana-431	128	22	normal	normal	ADJ
cana-431	128	23	diabetic	diabetic	ADJ
cana-431	128	24	range	range	NOUN
cana-431	128	25	values	value	NOUN
cana-431	128	26	p1	p1	PROPN
cana-431	128	27	:	:	PUNCT
cana-431	128	28	this	this	DET
cana-431	128	29	parameter	parameter	NOUN
cana-431	128	30	represents	represent	VERB
cana-431	128	31	the	the	DET
cana-431	128	32	rate	rate	NOUN
cana-431	128	33	at	at	ADP
cana-431	128	34	which	which	PRON
cana-431	128	35	glucose	glucose	NOUN
cana-431	128	36	disappears	disappear	VERB
cana-431	128	37	from	from	ADP
cana-431	128	38	the	the	DET
cana-431	128	39	bloodstream	bloodstream	NOUN
cana-431	128	40	,	,	PUNCT
cana-431	128	41	reflecting	reflect	VERB
cana-431	128	42	factors	factor	NOUN
cana-431	128	43	such	such	ADJ
cana-431	128	44	as	as	ADP
cana-431	128	45	glucose	glucose	NOUN
cana-431	128	46	uptake	uptake	NOUN
cana-431	128	47	by	by	ADP
cana-431	128	48	tissues	tissue	NOUN
cana-431	128	49	and	and	CCONJ
cana-431	128	50	organs	organ	NOUN
cana-431	128	51	,	,	PUNCT
cana-431	128	52	glycogen	glycogen	NOUN
cana-431	128	53	synthesis	synthesis	NOUN
cana-431	128	54	,	,	PUNCT
cana-431	128	55	and	and	CCONJ
cana-431	128	56	glucose	glucose	NOUN
cana-431	128	57	utilization	utilization	NOUN
cana-431	128	58	for	for	ADP
cana-431	128	59	energy	energy	NOUN
cana-431	128	60	.	.	PUNCT
cana-431	129	1	higher	high	ADJ
cana-431	129	2	p	p	NOUN
cana-431	129	3	1	1	NUM
cana-431	129	4	value	value	NOUN
cana-431	129	5	indicates	indicate	VERB
cana-431	129	6	faster	fast	ADJ
cana-431	129	7	glucose	glucose	NOUN
cana-431	129	8	disappearance	disappearance	NOUN
cana-431	129	9	,	,	PUNCT
cana-431	129	10	while	while	SCONJ
cana-431	129	11	a	a	DET
cana-431	129	12	lower	low	ADJ
cana-431	129	13	value	value	NOUN
cana-431	129	14	suggests	suggest	VERB
cana-431	129	15	slower	slow	ADJ
cana-431	129	16	clearance	clearance	NOUN
cana-431	129	17	.	.	PUNCT
cana-431	130	1	assume	assume	VERB
cana-431	130	2	the	the	DET
cana-431	130	3	following	follow	VERB
cana-431	130	4	parameter	parameter	NOUN
cana-431	130	5	values	value	NOUN
cana-431	130	6	and	and	CCONJ
cana-431	130	7	initial	initial	ADJ
cana-431	130	8	conditions	condition	NOUN
cana-431	130	9	for	for	ADP
cana-431	130	10	our	our	PRON
cana-431	130	11	numerical	numerical	PROPN
cana-431	130	12	simulation	simulation	PROPN
cana-431	130	13	:	:	PUNCT
cana-431	130	14	basal	basal	VERB
cana-431	130	15	glucose	glucose	NOUN
cana-431	130	16	concentration	concentration	NOUN
cana-431	130	17	gb	gb	NOUN
cana-431	130	18	:	:	PUNCT
cana-431	130	19	90	90	NUM
cana-431	130	20	mg	mg	PROPN
cana-431	130	21	/	/	SYM
cana-431	130	22	dl	dl	PROPN
cana-431	130	23	p1	p1	PROPN
cana-431	130	24	rate	rate	NOUN
cana-431	130	25	constant	constant	ADJ
cana-431	130	26	:	:	PUNCT
cana-431	130	27	0.1	0.1	NUM
cana-431	130	28	1	1	NUM
cana-431	130	29	/	/	SYM
cana-431	130	30	min	min	NOUN
cana-431	130	31	initial	initial	ADJ
cana-431	130	32	concentration	concentration	NOUN
cana-431	130	33	of	of	ADP
cana-431	130	34	glucose	glucose	NOUN
cana-431	130	35	:	:	PUNCT
cana-431	130	36	g	g	PROPN
cana-431	130	37	(	(	PUNCT
cana-431	130	38	t	t	PROPN
cana-431	130	39	):	):	PUNCT
cana-431	130	40	120	120	NUM
cana-431	130	41	mg	mg	PROPN
cana-431	130	42	/	/	SYM
cana-431	130	43	dl	dl	PROPN
cana-431	130	44	(	(	PUNCT
cana-431	130	45	slightly	slightly	ADV
cana-431	130	46	elevated	elevated	ADJ
cana-431	130	47	)	)	PUNCT
cana-431	130	48	insulin	insulin	NOUN
cana-431	130	49	action	action	NOUN
cana-431	130	50	effectiveness	effectiveness	NOUN
cana-431	130	51	:	:	PUNCT
cana-431	131	1	x	x	X
cana-431	131	2	(	(	PUNCT
cana-431	131	3	t	t	NOUN
cana-431	131	4	)	)	PUNCT
cana-431	131	5	=	=	NOUN
cana-431	131	6	0.01	0.01	NUM
cana-431	131	7	𝑑𝐺(𝑡	𝑑𝐺(𝑡	NOUN
cana-431	131	8	)	)	PUNCT
cana-431	131	9	𝑑𝑡	𝑑𝑡	ADP
cana-431	131	10	=	=	SYM
cana-431	131	11	−𝑝1	−𝑝1	PROPN
cana-431	131	12	⋅	⋅	X
cana-431	131	13	(	(	PUNCT
cana-431	131	14	𝐺(𝑡	𝐺(𝑡	NOUN
cana-431	131	15	)	)	PUNCT
cana-431	131	16	−	−	ADP
cana-431	132	1	𝐺𝑏	𝐺𝑏	PROPN
cana-431	132	2	)	)	PUNCT
cana-431	132	3	−	−	PROPN
cana-431	132	4	𝑋(𝑡	𝑋(𝑡	NUM
cana-431	132	5	)	)	PUNCT
cana-431	132	6	⋅	⋅	PROPN
cana-431	132	7	𝐺(𝑡	𝐺(𝑡	NUM
cana-431	132	8	)	)	PUNCT
cana-431	132	9	this	this	PRON
cana-431	132	10	is	be	AUX
cana-431	132	11	ordinary	ordinary	ADJ
cana-431	132	12	differential	differential	ADJ
cana-431	132	13	equation	equation	NOUN
cana-431	132	14	∫	∫	PROPN
cana-431	133	1	𝑑𝐺(𝑡	𝑑𝐺(𝑡	ADP
cana-431	133	2	)	)	PUNCT
cana-431	134	1	=	=	VERB
cana-431	134	2	∫[−𝑝1	∫[−𝑝1	PROPN
cana-431	134	3	⋅	⋅	PROPN
cana-431	134	4	(	(	PUNCT
cana-431	134	5	𝐺(𝑡	𝐺(𝑡	NOUN
cana-431	134	6	)	)	PUNCT
cana-431	134	7	−	−	ADP
cana-431	135	1	𝐺𝑏	𝐺𝑏	PROPN
cana-431	135	2	)	)	PUNCT
cana-431	135	3	−	−	PROPN
cana-431	135	4	𝑋(𝑡	𝑋(𝑡	NUM
cana-431	135	5	)	)	PUNCT
cana-431	135	6	⋅	⋅	PROPN
cana-431	135	7	𝐺(𝑡)]𝑑𝑡	𝐺(𝑡)]𝑑𝑡	PROPN
cana-431	135	8	=	=	SYM
cana-431	135	9	∫[−0.11	∫[−0.11	ADJ
cana-431	135	10	∗	∗	NOUN
cana-431	135	11	(	(	PUNCT
cana-431	135	12	120	120	NUM
cana-431	135	13	–	–	SYM
cana-431	135	14	90	90	NUM
cana-431	135	15	)	)	PUNCT
cana-431	135	16	−	−	NOUN
cana-431	135	17	0.01	0.01	NUM
cana-431	135	18	∗	∗	NOUN
cana-431	135	19	120]dt	120]dt	NUM
cana-431	135	20	g(t	g(t	PROPN
cana-431	135	21	)	)	PUNCT
cana-431	135	22	=	=	PUNCT
cana-431	135	23	4.5	4.5	NUM
cana-431	135	24	t	t	NOUN
cana-431	135	25	mg	mg	PROPN
cana-431	135	26	/	/	SYM
cana-431	135	27	dl	dl	PROPN
cana-431	135	28	glucose	glucose	NOUN
cana-431	135	29	concentration	concentration	NOUN
cana-431	135	30	rate	rate	NOUN
cana-431	135	31	𝑑𝐼(𝑡	𝑑𝐼(𝑡	NUM
cana-431	135	32	)	)	PUNCT
cana-431	135	33	𝑑𝑡	𝑑𝑡	ADP
cana-431	135	34	=	=	SYM
cana-431	135	35	s(t)⋅[g(t)−gb	s(t)⋅[g(t)−gb	X
cana-431	135	36	]	]	PUNCT
cana-431	135	37	−p2⋅i(t	−p2⋅i(t	NOUN
cana-431	135	38	)	)	PUNCT
cana-431	135	39	insulin	insulin	NOUN
cana-431	135	40	sensitivity	sensitivity	NOUN
cana-431	135	41	factor	factor	NOUN
cana-431	135	42	s(t	s(t	PROPN
cana-431	135	43	)	)	PUNCT
cana-431	135	44	=	=	NOUN
cana-431	135	45	0.05	0.05	NUM
cana-431	135	46	p2	p2	NOUN
cana-431	135	47	:	:	PUNCT
cana-431	135	48	clearance	clearance	NOUN
cana-431	135	49	rate	rate	NOUN
cana-431	135	50	constant	constant	ADJ
cana-431	135	51	0.02	0.02	NUM
cana-431	135	52	basal	basal	NOUN
cana-431	135	53	glucose	glucose	NOUN
cana-431	135	54	concentration	concentration	NOUN
cana-431	135	55	gb	gb	NOUN
cana-431	135	56	:	:	PUNCT
cana-431	135	57	90	90	NUM
cana-431	135	58	mg	mg	NUM
cana-431	135	59	/	/	SYM
cana-431	135	60	dl	dl	PROPN
cana-431	135	61	i(t	i(t	PROPN
cana-431	135	62	)	)	PUNCT
cana-431	135	63	=	=	SYM
cana-431	136	1	15	15	NUM
cana-431	136	2	current	current	ADJ
cana-431	136	3	insulin	insulin	NOUN
cana-431	136	4	concentration	concentration	NOUN
cana-431	136	5	∫	∫	PROPN
cana-431	136	6	𝑑𝐼(𝑡	𝑑𝐼(𝑡	NUM
cana-431	136	7	)	)	PUNCT
cana-431	136	8	=	=	SYM
cana-431	136	9	∫[𝑆(𝑡	∫[𝑆(𝑡	X
cana-431	136	10	)	)	PUNCT
cana-431	136	11	⋅	⋅	PROPN
cana-431	136	12	(	(	PUNCT
cana-431	136	13	𝐺(𝑡	𝐺(𝑡	NOUN
cana-431	136	14	)	)	PUNCT
cana-431	136	15	−	−	ADP
cana-431	137	1	𝐺𝑏	𝐺𝑏	PROPN
cana-431	137	2	)	)	PUNCT
cana-431	137	3	−	−	PROPN
cana-431	137	4	𝑝2	𝑝2	NOUN
cana-431	137	5	⋅	⋅	PROPN
cana-431	137	6	𝐼(𝑡)]dt	𝐼(𝑡)]dt	PROPN
cana-431	137	7	=	=	SYM
cana-431	137	8	∫[0.05	∫[0.05	NOUN
cana-431	137	9	∗	∗	NOUN
cana-431	137	10	(	(	PUNCT
cana-431	137	11	120	120	NUM
cana-431	137	12	−	−	NUM
cana-431	137	13	90	90	NUM
cana-431	137	14	)	)	PUNCT
cana-431	137	15	–	–	PUNCT
cana-431	137	16	0.02	0.02	NUM
cana-431	137	17	∗	∗	NOUN
cana-431	137	18	15]dt	15]dt	NUM
cana-431	137	19	i(t	i(t	NOUN
cana-431	137	20	)	)	PUNCT
cana-431	137	21	=	=	SYM
cana-431	137	22	1.2	1.2	NUM
cana-431	137	23	t	t	NOUN
cana-431	137	24	unit	unit	NOUN
cana-431	137	25	/	/	SYM
cana-431	137	26	l	l	NOUN
cana-431	137	27	insulin	insulin	NOUN
cana-431	137	28	concentration	concentration	NOUN
cana-431	137	29	over	over	ADP
cana-431	137	30	time	time	NOUN
cana-431	137	31	adjust	adjust	VERB
cana-431	137	32	the	the	DET
cana-431	137	33	model	model	NOUN
cana-431	137	34	parameters	parameter	NOUN
cana-431	137	35	,	,	PUNCT
cana-431	137	36	initial	initial	ADJ
cana-431	137	37	conditions	condition	NOUN
cana-431	137	38	,	,	PUNCT
cana-431	137	39	and	and	CCONJ
cana-431	137	40	glucose	glucose	NOUN
cana-431	137	41	concentration	concentration	NOUN
cana-431	137	42	function	function	NOUN
cana-431	137	43	as	as	SCONJ
cana-431	137	44	needed	need	VERB
cana-431	137	45	to	to	PART
cana-431	137	46	fit	fit	VERB
cana-431	137	47	the	the	DET
cana-431	137	48	specific	specific	ADJ
cana-431	137	49	scenario	scenario	NOUN
cana-431	137	50	or	or	CCONJ
cana-431	137	51	data	datum	NOUN
cana-431	137	52	.	.	PUNCT
cana-431	138	1	conclusion	conclusion	NOUN
cana-431	138	2	:	:	PUNCT
cana-431	138	3	a	a	DET
cana-431	138	4	mathematical	mathematical	ADJ
cana-431	138	5	model	model	NOUN
cana-431	138	6	included	include	VERB
cana-431	138	7	hyperglycaemia	hyperglycaemia	NOUN
cana-431	138	8	,	,	PUNCT
cana-431	138	9	hypoglycaemia	hypoglycaemia	NOUN
cana-431	138	10	,	,	PUNCT
cana-431	138	11	cardiovascular	cardiovascular	ADJ
cana-431	138	12	complications	complication	NOUN
cana-431	138	13	,	,	PUNCT
cana-431	138	14	neuropathy	neuropathy	ADJ
cana-431	138	15	,	,	PUNCT
cana-431	138	16	nephropathy	nephropathy	ADJ
cana-431	138	17	,	,	PUNCT
cana-431	138	18	retinopathy	retinopathy	ADJ
cana-431	138	19	,	,	PUNCT
cana-431	138	20	skin	skin	NOUN
cana-431	138	21	complications	complication	NOUN
cana-431	138	22	,	,	PUNCT
cana-431	138	23	gastroparesis	gastroparesis	NOUN
cana-431	138	24	,	,	PUNCT
cana-431	138	25	and	and	CCONJ
cana-431	138	26	complications	complication	NOUN
cana-431	138	27	in	in	ADP
cana-431	138	28	communications	communication	NOUN
cana-431	138	29	on	on	ADP
cana-431	138	30	applied	apply	VERB
cana-431	138	31	nonlinear	nonlinear	ADJ
cana-431	138	32	analysis	analysis	NOUN
cana-431	138	33	issn	issn	NOUN
cana-431	138	34	:	:	PUNCT
cana-431	138	35	1074	1074	NUM
cana-431	138	36	-	-	PUNCT
cana-431	138	37	133x	133x	NUM
cana-431	138	38	vol	vol	NOUN
cana-431	138	39	31	31	NUM
cana-431	138	40	no	no	NOUN
cana-431	138	41	.	.	NOUN
cana-431	138	42	1	1	NUM
cana-431	138	43	(	(	PUNCT
cana-431	138	44	2024	2024	NUM
cana-431	138	45	)	)	PUNCT
cana-431	139	1	296	296	NUM
cana-431	139	2	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	139	3	pregnancy	pregnancy	NOUN
cana-431	139	4	.	.	PUNCT
cana-431	140	1	developing	develop	VERB
cana-431	140	2	a	a	DET
cana-431	140	3	model	model	NOUN
cana-431	140	4	that	that	PRON
cana-431	140	5	accounts	account	VERB
cana-431	140	6	for	for	ADP
cana-431	140	7	all	all	DET
cana-431	140	8	these	these	DET
cana-431	140	9	complications	complication	NOUN
cana-431	140	10	is	be	AUX
cana-431	140	11	challenging	challenge	VERB
cana-431	140	12	due	due	ADJ
cana-431	140	13	to	to	ADP
cana-431	140	14	the	the	DET
cana-431	140	15	complexity	complexity	NOUN
cana-431	140	16	and	and	CCONJ
cana-431	140	17	heterogeneity	heterogeneity	NOUN
cana-431	140	18	of	of	ADP
cana-431	140	19	diabetes	diabetes	NOUN
cana-431	140	20	.	.	PUNCT
cana-431	141	1	model	model	NOUN
cana-431	141	2	simulates	simulate	VERB
cana-431	141	3	the	the	DET
cana-431	141	4	dynamic	dynamic	ADJ
cana-431	141	5	interaction	interaction	NOUN
cana-431	141	6	between	between	ADP
cana-431	141	7	glucose	glucose	NOUN
cana-431	141	8	and	and	CCONJ
cana-431	141	9	insulin	insulin	NOUN
cana-431	141	10	,	,	PUNCT
cana-431	141	11	considering	consider	VERB
cana-431	141	12	glucose	glucose	NOUN
cana-431	141	13	production	production	NOUN
cana-431	141	14	,	,	PUNCT
cana-431	141	15	utilization	utilization	NOUN
cana-431	141	16	,	,	PUNCT
cana-431	141	17	and	and	CCONJ
cana-431	141	18	insulin	insulin	NOUN
cana-431	141	19	action	action	NOUN
cana-431	141	20	.	.	PUNCT
cana-431	142	1	insulin	insulin	NOUN
cana-431	142	2	action	action	NOUN
cana-431	142	3	is	be	AUX
cana-431	142	4	influenced	influence	VERB
cana-431	142	5	by	by	ADP
cana-431	142	6	both	both	CCONJ
cana-431	142	7	the	the	DET
cana-431	142	8	insulin	insulin	NOUN
cana-431	142	9	concentration	concentration	NOUN
cana-431	142	10	and	and	CCONJ
cana-431	142	11	its	its	PRON
cana-431	142	12	decay	decay	NOUN
cana-431	142	13	rate	rate	NOUN
cana-431	142	14	.	.	PUNCT
cana-431	143	1	the	the	DET
cana-431	143	2	model	model	NOUN
cana-431	143	3	can	can	AUX
cana-431	143	4	be	be	AUX
cana-431	143	5	extended	extend	VERB
cana-431	143	6	to	to	PART
cana-431	143	7	include	include	VERB
cana-431	143	8	meal	meal	NOUN
cana-431	143	9	intake	intake	NOUN
cana-431	143	10	,	,	PUNCT
cana-431	143	11	physical	physical	ADJ
cana-431	143	12	activity	activity	NOUN
cana-431	143	13	,	,	PUNCT
cana-431	143	14	and	and	CCONJ
cana-431	143	15	more	more	ADV
cana-431	143	16	sophisticated	sophisticated	ADJ
cana-431	143	17	representations	representation	NOUN
cana-431	143	18	of	of	ADP
cana-431	143	19	insulin	insulin	NOUN
cana-431	143	20	secretion	secretion	NOUN
cana-431	143	21	.	.	PUNCT
cana-431	144	1	summarize	summarize	VERB
cana-431	144	2	the	the	DET
cana-431	144	3	key	key	ADJ
cana-431	144	4	challenges	challenge	NOUN
cana-431	144	5	,	,	PUNCT
cana-431	144	6	approaches	approach	NOUN
cana-431	144	7	,	,	PUNCT
cana-431	144	8	and	and	CCONJ
cana-431	144	9	recent	recent	ADJ
cana-431	144	10	advances	advance	NOUN
cana-431	144	11	in	in	ADP
cana-431	144	12	parameter	parameter	NOUN
cana-431	144	13	estimation	estimation	NOUN
cana-431	144	14	for	for	ADP
cana-431	144	15	mathematical	mathematical	ADJ
cana-431	144	16	model	model	NOUN
cana-431	144	17	.	.	PUNCT
cana-431	145	1	emphasize	emphasize	VERB
cana-431	145	2	the	the	DET
cana-431	145	3	crucial	crucial	ADJ
cana-431	145	4	role	role	NOUN
cana-431	145	5	of	of	ADP
cana-431	145	6	accurate	accurate	ADJ
cana-431	145	7	parameter	parameter	NOUN
cana-431	145	8	estimation	estimation	NOUN
cana-431	145	9	in	in	ADP
cana-431	145	10	advancing	advance	VERB
cana-431	145	11	our	our	PRON
cana-431	145	12	understanding	understanding	NOUN
cana-431	145	13	of	of	ADP
cana-431	145	14	cellular	cellular	ADJ
cana-431	145	15	processes	process	NOUN
cana-431	145	16	and	and	CCONJ
cana-431	145	17	potential	potential	ADJ
cana-431	145	18	applications	application	NOUN
cana-431	145	19	in	in	ADP
cana-431	145	20	precision	precision	NOUN
cana-431	145	21	medicine	medicine	NOUN
cana-431	145	22	and	and	CCONJ
cana-431	145	23	synthetic	synthetic	ADJ
cana-431	145	24	biology	biology	NOUN
cana-431	145	25	.	.	PUNCT
cana-431	146	1	these	these	DET
cana-431	146	2	references	reference	NOUN
cana-431	146	3	provide	provide	VERB
cana-431	146	4	insights	insight	NOUN
cana-431	146	5	into	into	ADP
cana-431	146	6	the	the	DET
cana-431	146	7	diverse	diverse	ADJ
cana-431	146	8	applications	application	NOUN
cana-431	146	9	of	of	ADP
cana-431	146	10	immunotherapy	immunotherapy	NOUN
cana-431	146	11	beyond	beyond	ADP
cana-431	146	12	cancer	cancer	NOUN
cana-431	146	13	.	.	PUNCT
cana-431	147	1	immunotherapeutic	immunotherapeutic	ADJ
cana-431	147	2	strategies	strategy	NOUN
cana-431	147	3	continue	continue	VERB
cana-431	147	4	to	to	PART
cana-431	147	5	evolve	evolve	VERB
cana-431	147	6	,	,	PUNCT
cana-431	147	7	offering	offer	VERB
cana-431	147	8	new	new	ADJ
cana-431	147	9	hope	hope	NOUN
cana-431	147	10	for	for	ADP
cana-431	147	11	the	the	DET
cana-431	147	12	treatment	treatment	NOUN
cana-431	147	13	of	of	ADP
cana-431	147	14	various	various	ADJ
cana-431	147	15	medical	medical	ADJ
cana-431	147	16	conditions	condition	NOUN
cana-431	147	17	.	.	PUNCT
cana-431	148	1	it	it	PRON
cana-431	148	2	's	be	AUX
cana-431	148	3	necessary	necessary	ADJ
cana-431	148	4	that	that	SCONJ
cana-431	148	5	people	people	NOUN
cana-431	148	6	with	with	ADP
cana-431	148	7	diabetes	diabetes	NOUN
cana-431	148	8	work	work	VERB
cana-431	148	9	closely	closely	ADV
cana-431	148	10	with	with	SCONJ
cana-431	148	11	medical	medical	ADJ
cana-431	148	12	professionals	professional	NOUN
cana-431	148	13	to	to	PART
cana-431	148	14	create	create	VERB
cana-431	148	15	personalized	personalized	ADJ
cana-431	148	16	treatment	treatment	NOUN
cana-431	148	17	programs	program	NOUN
cana-431	148	18	that	that	PRON
cana-431	148	19	take	take	VERB
cana-431	148	20	these	these	DET
cana-431	148	21	variables	variable	NOUN
cana-431	148	22	into	into	ADP
cana-431	148	23	account	account	NOUN
cana-431	148	24	.	.	PUNCT
cana-431	149	1	lifestyle	lifestyle	NOUN
cana-431	149	2	modifications	modification	NOUN
cana-431	149	3	,	,	PUNCT
cana-431	149	4	medication	medication	NOUN
cana-431	149	5	management	management	NOUN
cana-431	149	6	,	,	PUNCT
cana-431	149	7	and	and	CCONJ
cana-431	149	8	regular	regular	ADJ
cana-431	149	9	monitoring	monitoring	NOUN
cana-431	149	10	are	be	AUX
cana-431	149	11	key	key	ADJ
cana-431	149	12	components	component	NOUN
cana-431	149	13	of	of	ADP
cana-431	149	14	diabetes	diabetes	NOUN
cana-431	149	15	care	care	NOUN
cana-431	149	16	.	.	PUNCT
cana-431	150	1	references	reference	NOUN
cana-431	150	2	:	:	PUNCT
cana-431	151	1	[	[	X
cana-431	151	2	1	1	X
cana-431	151	3	]	]	X
cana-431	151	4	gesham	gesham	PROPN
cana-431	151	5	magombedze	magombedze	PROPN
cana-431	151	6	,	,	PUNCT
cana-431	151	7	polite	polite	ADJ
cana-431	151	8	ndurua	ndurua	NOUN
cana-431	151	9	,	,	PUNCT
cana-431	151	10	claver	claver	NOUN
cana-431	151	11	p.	p.	NOUN
cana-431	151	12	bhunua	bhunua	PROPN
cana-431	151	13	,	,	PUNCT
cana-431	151	14	steady	steady	ADJ
cana-431	151	15	mushayabasa	mushayabasa	NOUN
cana-431	151	16	.	.	PUNCT
cana-431	152	1	“	"	PUNCT
cana-431	152	2	mathematical	mathematical	ADJ
cana-431	152	3	modelling	modelling	NOUN
cana-431	152	4	of	of	ADP
cana-431	152	5	immune	immune	ADJ
cana-431	152	6	regulation	regulation	NOUN
cana-431	152	7	of	of	ADP
cana-431	152	8	type	type	NOUN
cana-431	152	9	1	1	NUM
cana-431	152	10	diabetes	diabete	NOUN
cana-431	152	11	”	"	PUNCT
cana-431	152	12	2010	2010	NUM
cana-431	152	13	elsevier	elsevier	PROPN
cana-431	152	14	ireland	ireland	PROPN
cana-431	152	15	ltd	ltd	PROPN
cana-431	152	16	.	.	PUNCT
cana-431	153	1	[	[	X
cana-431	153	2	2	2	NUM
cana-431	153	3	]	]	X
cana-431	153	4	wiam	wiam	PROPN
cana-431	153	5	boutayeb	boutayeb	PROPN
cana-431	153	6	,	,	PUNCT
cana-431	153	7	mohamed	mohamed	PROPN
cana-431	153	8	e.	e.	PROPN
cana-431	153	9	n.	n.	PROPN
cana-431	153	10	lamlili	lamlili	PROPN
cana-431	153	11	,	,	PUNCT
cana-431	153	12	abdesslam	abdesslam	PROPN
cana-431	153	13	boutayeb	boutayeb	PROPN
cana-431	153	14	,	,	PUNCT
cana-431	153	15	mohamed	mohamed	PROPN
cana-431	153	16	derouich	derouich	PROPN
cana-431	153	17	.	.	PUNCT
cana-431	154	1	“	"	PUNCT
cana-431	154	2	mathematical	mathematical	ADJ
cana-431	154	3	modelling	modelling	NOUN
cana-431	154	4	and	and	CCONJ
cana-431	154	5	simulation	simulation	NOUN
cana-431	154	6	of	of	ADP
cana-431	154	7	β	β	NOUN
cana-431	154	8	-	-	NOUN
cana-431	154	9	cell	cell	NOUN
cana-431	154	10	mass	mass	NOUN
cana-431	154	11	,	,	PUNCT
cana-431	154	12	insulin	insulin	NOUN
cana-431	154	13	and	and	CCONJ
cana-431	154	14	glucose	glucose	NOUN
cana-431	154	15	dynamics	dynamic	NOUN
cana-431	154	16	:	:	PUNCT
cana-431	154	17	effect	effect	NOUN
cana-431	154	18	of	of	ADP
cana-431	154	19	genetic	genetic	ADJ
cana-431	154	20	predisposition	predisposition	NOUN
cana-431	154	21	to	to	ADP
cana-431	154	22	diabetes	diabetes	NOUN
cana-431	154	23	”	"	PUNCT
cana-431	154	24	(	(	PUNCT
cana-431	154	25	2014	2014	NUM
cana-431	154	26	)	)	PUNCT
cana-431	154	27	7	7	NUM
cana-431	154	28	,	,	PUNCT
cana-431	154	29	330	330	NUM
cana-431	154	30	-	-	SYM
cana-431	154	31	342	342	NUM
cana-431	154	32	j.	j.	PROPN
cana-431	154	33	biomedical	biomedical	PROPN
cana-431	154	34	science	science	NOUN
cana-431	154	35	and	and	CCONJ
cana-431	154	36	engineering	engineering	NOUN
cana-431	154	37	[	[	X
cana-431	154	38	3	3	NUM
cana-431	154	39	]	]	X
cana-431	154	40	waleed	waleed	PROPN
cana-431	154	41	noori	noori	PROPN
cana-431	154	42	hussein	hussein	PROPN
cana-431	154	43	,	,	PUNCT
cana-431	154	44	zainab	zainab	PROPN
cana-431	154	45	muzahim	muzahim	PROPN
cana-431	154	46	mohammed	mohammed	PROPN
cana-431	154	47	.	.	PUNCT
cana-431	155	1	“	"	PUNCT
cana-431	155	2	identifying	identify	VERB
cana-431	155	3	risk	risk	NOUN
cana-431	155	4	factors	factor	NOUN
cana-431	155	5	associated	associate	VERB
cana-431	155	6	with	with	ADP
cana-431	155	7	type	type	NOUN
cana-431	155	8	2	2	NUM
cana-431	155	9	diabetes	diabetes	NOUN
cana-431	155	10	based	base	VERB
cana-431	155	11	on	on	ADP
cana-431	155	12	data	datum	NOUN
cana-431	155	13	analysis	analysis	NOUN
cana-431	155	14	”	"	PUNCT
cana-431	155	15	(	(	PUNCT
cana-431	155	16	2022)2665	2022)2665	NUM
cana-431	155	17	-	-	SYM
cana-431	155	18	9174	9174	NUM
cana-431	155	19	,	,	PUNCT
cana-431	155	20	published	publish	VERB
cana-431	155	21	by	by	ADP
cana-431	155	22	elsevier	elsevier	PROPN
cana-431	155	23	ltd	ltd	PROPN
cana-431	156	1	[	[	X
cana-431	156	2	4	4	NUM
cana-431	156	3	]	]	PUNCT
cana-431	156	4	andrea	andrea	PROPN
cana-431	156	5	de	de	PROPN
cana-431	156	6	gaetano	gaetano	PROPN
cana-431	156	7	,	,	PUNCT
cana-431	156	8	thomas	thomas	PROPN
cana-431	156	9	hardy	hardy	PROPN
cana-431	156	10	,	,	PUNCT
cana-431	156	11	benoit	benoit	NOUN
cana-431	156	12	beck	beck	PROPN
cana-431	156	13	,	,	PUNCT
cana-431	156	14	“	"	PUNCT
cana-431	156	15	mathematical	mathematical	ADJ
cana-431	156	16	models	model	NOUN
cana-431	156	17	of	of	ADP
cana-431	156	18	diabetes	diabetes	NOUN
cana-431	156	19	progression”,2008	progression”,2008	PROPN
cana-431	156	20	,	,	PUNCT
cana-431	156	21	ajp	ajp	PROPN
cana-431	156	22	endocrinology	endocrinology	NOUN
cana-431	156	23	and	and	CCONJ
cana-431	156	24	metabolism	metabolism	NOUN
cana-431	156	25	.	.	PUNCT
cana-431	157	1	[	[	X
cana-431	157	2	5	5	NUM
cana-431	157	3	]	]	PUNCT
cana-431	157	4	r.	r.	PROPN
cana-431	157	5	ungaro	ungaro	PROPN
cana-431	157	6	and	and	CCONJ
cana-431	157	7	j.-f	j.-f	NOUN
cana-431	157	8	.	.	PUNCT
cana-431	158	1	colombel	colombel	VERB
cana-431	158	2	"	"	PUNCT
cana-431	158	3	immunotherapy	immunotherapy	NOUN
cana-431	158	4	in	in	ADP
cana-431	158	5	inflammatory	inflammatory	ADJ
cana-431	158	6	bowel	bowel	NOUN
cana-431	158	7	disease	disease	NOUN
cana-431	158	8	:	:	PUNCT
cana-431	158	9	novel	novel	NOUN
cana-431	158	10	and	and	CCONJ
cana-431	158	11	emerging	emerge	VERB
cana-431	158	12	treatments".2021	treatments".2021	NUM
cana-431	158	13	,	,	PUNCT
cana-431	158	14	the	the	DET
cana-431	158	15	lancet	lancet	NOUN
cana-431	158	16	gastroenterology	gastroenterology	NOUN
cana-431	158	17	&	&	CCONJ
cana-431	158	18	hepatology	hepatology	NOUN
cana-431	158	19	.	.	PUNCT
cana-431	159	1	[	[	X
cana-431	159	2	6	6	NUM
cana-431	159	3	]	]	PUNCT
cana-431	159	4	c.	c.	PROPN
cana-431	159	5	mathews	mathews	PROPN
cana-431	159	6	and	and	CCONJ
cana-431	159	7	d.	d.	PROPN
cana-431	159	8	v.	v.	PROPN
cana-431	159	9	dayan	dayan	PROPN
cana-431	159	10	.	.	PUNCT
cana-431	160	1	“immunotherapeutic	“immunotherapeutic	ADJ
cana-431	160	2	strategies	strategy	NOUN
cana-431	160	3	for	for	ADP
cana-431	160	4	type	type	NOUN
cana-431	160	5	1	1	NUM
cana-431	160	6	diabetes	diabete	NOUN
cana-431	160	7	”	"	PUNCT
cana-431	160	8	,	,	PUNCT
cana-431	160	9	2014	2014	NUM
cana-431	160	10	,	,	PUNCT
cana-431	160	11	european	european	ADJ
cana-431	160	12	journal	journal	NOUN
cana-431	160	13	of	of	ADP
cana-431	160	14	immunology	immunology	NOUN
cana-431	160	15	.	.	PUNCT
cana-431	161	1	[	[	X
cana-431	161	2	7	7	NUM
cana-431	161	3	]	]	SYM
cana-431	161	4	wellars	wellar	NOUN
cana-431	161	5	banzi	banzi	PROPN
cana-431	161	6	,	,	PUNCT
cana-431	161	7	immaculate	immaculate	NOUN
cana-431	161	8	kambutse	kambutse	NOUN
cana-431	161	9	,	,	PUNCT
cana-431	161	10	vincent	vincent	PROPN
cana-431	161	11	dusabejambo	dusabejambo	PROPN
cana-431	161	12	,	,	PUNCT
cana-431	161	13	eric	eric	PROPN
cana-431	161	14	rutaganda	rutaganda	PROPN
cana-431	161	15	.	.	PUNCT
cana-431	162	1	“	"	PUNCT
cana-431	162	2	mathematical	mathematical	ADJ
cana-431	162	3	modelling	modelling	NOUN
cana-431	162	4	of	of	ADP
cana-431	162	5	glucose	glucose	NOUN
cana-431	162	6	-	-	PUNCT
cana-431	162	7	insulin	insulin	NOUN
cana-431	162	8	system	system	NOUN
cana-431	162	9	and	and	CCONJ
cana-431	162	10	test	test	NOUN
cana-431	162	11	of	of	ADP
cana-431	162	12	abnormalities	abnormality	NOUN
cana-431	162	13	of	of	ADP
cana-431	162	14	type	type	NOUN
cana-431	162	15	2	2	NUM
cana-431	162	16	diabetic	diabetic	NOUN
cana-431	162	17	patients”.2021	patients”.2021	NOUN
cana-431	162	18	,	,	PUNCT
cana-431	162	19	hindawi	hindawi	ADJ
cana-431	162	20	international	international	ADJ
cana-431	162	21	journal	journal	NOUN
cana-431	162	22	of	of	ADP
cana-431	162	23	mathematics	mathematics	PROPN
cana-431	162	24	and	and	CCONJ
cana-431	162	25	mathematical	mathematical	ADJ
cana-431	162	26	sciences	science	NOUN
cana-431	162	27	[	[	X
cana-431	162	28	8	8	NUM
cana-431	162	29	]	]	X
cana-431	162	30	mohammad	mohammad	PROPN
cana-431	162	31	al	al	PROPN
cana-431	162	32	shurbaji	shurbaji	PROPN
cana-431	162	33	,	,	PUNCT
cana-431	162	34	lamis	lamis	PROPN
cana-431	162	35	abdul	abdul	PROPN
cana-431	162	36	kader	kader	PROPN
cana-431	162	37	,	,	PUNCT
cana-431	162	38	hadia	hadia	PROPN
cana-431	162	39	hannan	hannan	PROPN
cana-431	162	40	,	,	PUNCT
cana-431	162	41	maruf	maruf	ADJ
cana-431	162	42	mortula	mortula	NOUN
cana-431	162	43	and	and	CCONJ
cana-431	162	44	ghaleb	ghaleb	PROPN
cana-431	162	45	a.	a.	NOUN
cana-431	162	46	husseini	husseini	PROPN
cana-431	162	47	.2023	.2023	PROPN
cana-431	162	48	,	,	PUNCT
cana-431	162	49	“	"	PUNCT
cana-431	162	50	comprehensive	comprehensive	ADJ
cana-431	162	51	study	study	NOUN
cana-431	162	52	of	of	ADP
cana-431	162	53	a	a	DET
cana-431	162	54	diabetes	diabetes	NOUN
cana-431	162	55	mellitus	mellitus	PROPN
cana-431	162	56	mathematical	mathematical	ADJ
cana-431	162	57	model	model	NOUN
cana-431	162	58	using	use	VERB
cana-431	162	59	numerical	numerical	ADJ
cana-431	162	60	methods	method	NOUN
cana-431	162	61	with	with	ADP
cana-431	162	62	stability	stability	NOUN
cana-431	162	63	and	and	CCONJ
cana-431	162	64	parametric	parametric	ADJ
cana-431	162	65	analysis	analysis	NOUN
cana-431	162	66	.	.	PUNCT
cana-431	162	67	”	"	PUNCT
cana-431	163	1	[	[	X
cana-431	163	2	9	9	NUM
cana-431	163	3	]	]	PUNCT
cana-431	163	4	marzio	marzio	NOUN
cana-431	163	5	pennisi	pennisi	VERB
cana-431	163	6	.	.	PUNCT
cana-431	164	1	“	"	PUNCT
cana-431	164	2	a	a	DET
cana-431	164	3	mathematical	mathematical	ADJ
cana-431	164	4	model	model	NOUN
cana-431	164	5	of	of	ADP
cana-431	164	6	immune	immune	NOUN
cana-431	164	7	-	-	PUNCT
cana-431	164	8	system	system	NOUN
cana-431	164	9	-	-	PUNCT
cana-431	164	10	melanoma	melanoma	NOUN
cana-431	164	11	competition	competition	NOUN
cana-431	164	12	”	"	PUNCT
cana-431	164	13	,	,	PUNCT
cana-431	164	14	2012	2012	NUM
cana-431	164	15	,	,	PUNCT
cana-431	164	16	hindawi	hindawi	ADJ
cana-431	164	17	publishing	publishing	NOUN
cana-431	164	18	corporation	corporation	NOUN
cana-431	164	19	computational	computational	ADJ
cana-431	164	20	and	and	CCONJ
cana-431	164	21	mathematical	mathematical	ADJ
cana-431	164	22	methods	method	NOUN
cana-431	164	23	in	in	ADP
cana-431	164	24	medicine	medicine	NOUN
cana-431	164	25	.	.	PUNCT
cana-431	165	1	[	[	X
cana-431	165	2	10	10	NUM
cana-431	165	3	]	]	X
cana-431	165	4	a	a	DET
cana-431	165	5	boutayeb	boutayeb	ADJ
cana-431	165	6	,	,	PUNCT
cana-431	165	7	a.	a.	NOUN
cana-431	165	8	chetouani	chetouani	NOUN
cana-431	165	9	“	"	PUNCT
cana-431	165	10	a	a	DET
cana-431	165	11	critical	critical	ADJ
cana-431	165	12	review	review	NOUN
cana-431	165	13	of	of	ADP
cana-431	165	14	mathematical	mathematical	ADJ
cana-431	165	15	models	model	NOUN
cana-431	165	16	and	and	CCONJ
cana-431	165	17	data	datum	NOUN
cana-431	165	18	used	use	VERB
cana-431	165	19	in	in	ADP
cana-431	165	20	diabetology	diabetology	NOUN
cana-431	165	21	”	"	PUNCT
cana-431	165	22	,	,	PUNCT
cana-431	165	23	2006	2006	NUM
cana-431	165	24	,	,	PUNCT
cana-431	165	25	biomedical	biomedical	ADJ
cana-431	165	26	engineering	engineering	NOUN
cana-431	165	27	online	online	NOUN
cana-431	165	28	.	.	PUNCT
cana-431	166	1	communications	communication	NOUN
cana-431	166	2	on	on	ADP
cana-431	166	3	applied	apply	VERB
cana-431	166	4	nonlinear	nonlinear	ADJ
cana-431	166	5	analysis	analysis	NOUN
cana-431	166	6	issn	issn	NOUN
cana-431	166	7	:	:	PUNCT
cana-431	166	8	1074	1074	NUM
cana-431	166	9	-	-	PUNCT
cana-431	166	10	133x	133x	NUM
cana-431	166	11	vol	vol	NOUN
cana-431	166	12	31	31	NUM
cana-431	166	13	no	no	NOUN
cana-431	166	14	.	.	NOUN
cana-431	166	15	1	1	NUM
cana-431	166	16	(	(	PUNCT
cana-431	166	17	2024	2024	NUM
cana-431	166	18	)	)	PUNCT
cana-431	166	19	297	297	NUM
cana-431	166	20	https://internationalpubls.com	https://internationalpubls.com	X
cana-431	167	1	[	[	X
cana-431	167	2	11	11	NUM
cana-431	167	3	]	]	PUNCT
cana-431	167	4	mingju	mingju	NOUN
cana-431	167	5	ma	ma	PROPN
cana-431	167	6	and	and	CCONJ
cana-431	167	7	jun	jun	PROPN
cana-431	167	8	li	li	PROPN
cana-431	167	9	,	,	PUNCT
cana-431	167	10	“	"	PUNCT
cana-431	167	11	dynamics	dynamic	NOUN
cana-431	167	12	of	of	ADP
cana-431	167	13	a	a	DET
cana-431	167	14	glucose	glucose	NOUN
cana-431	167	15	–	–	PUNCT
cana-431	167	16	insulin	insulin	NOUN
cana-431	167	17	model	model	NOUN
cana-431	167	18	”	"	PUNCT
cana-431	167	19	,	,	PUNCT
cana-431	167	20	2022	2022	NUM
cana-431	167	21	,	,	PUNCT
cana-431	167	22	journal	journal	NOUN
cana-431	167	23	of	of	ADP
cana-431	167	24	biological	biological	ADJ
cana-431	167	25	dynamics	dynamic	NOUN
cana-431	167	26	.	.	PUNCT
cana-431	168	1	[	[	X
cana-431	168	2	12	12	NUM
cana-431	168	3	]	]	PUNCT
cana-431	168	4	andrea	andrea	PROPN
cana-431	168	5	mari	mari	PROPN
cana-431	168	6	“	"	PUNCT
cana-431	168	7	mathematical	mathematical	ADJ
cana-431	168	8	modelling	modelling	NOUN
cana-431	168	9	in	in	ADP
cana-431	168	10	glucose	glucose	NOUN
cana-431	168	11	metabolism	metabolism	NOUN
cana-431	168	12	and	and	CCONJ
cana-431	168	13	insulin	insulin	NOUN
cana-431	168	14	secretion”,2022	secretion”,2022	NOUN
cana-431	168	15	,	,	PUNCT
cana-431	168	16	current	current	ADJ
cana-431	168	17	opinion	opinion	NOUN
cana-431	168	18	in	in	ADP
cana-431	168	19	clinical	clinical	ADJ
cana-431	168	20	nutrition	nutrition	NOUN
cana-431	168	21	and	and	CCONJ
cana-431	168	22	metabolic	metabolic	NOUN
cana-431	168	23	care	care	NOUN
cana-431	168	24	.	.	PUNCT
cana-431	169	1	[	[	X
cana-431	169	2	13	13	NUM
cana-431	169	3	]	]	X
cana-431	169	4	v.	v.	ADP
cana-431	169	5	o.	o.	PROPN
cana-431	169	6	akinsola	akinsola	PROPN
cana-431	169	7	&	&	CCONJ
cana-431	169	8	t.	t.	PROPN
cana-431	169	9	o.	o.	PROPN
cana-431	169	10	oluyo	oluyo	PROPN
cana-431	169	11	“	"	PUNCT
cana-431	169	12	mathematical	mathematical	ADJ
cana-431	169	13	analysis	analysis	NOUN
cana-431	169	14	with	with	ADP
cana-431	169	15	numerical	numerical	ADJ
cana-431	169	16	solutions	solution	NOUN
cana-431	169	17	of	of	ADP
cana-431	169	18	the	the	DET
cana-431	169	19	mathematical	mathematical	ADJ
cana-431	169	20	model	model	NOUN
cana-431	169	21	for	for	ADP
cana-431	169	22	the	the	DET
cana-431	169	23	complications	complication	NOUN
cana-431	169	24	and	and	CCONJ
cana-431	169	25	control	control	NOUN
cana-431	169	26	of	of	ADP
cana-431	169	27	diabetes	diabete	NOUN
cana-431	169	28	mellitus”2019	mellitus”2019	X
cana-431	169	29	,	,	PUNCT
cana-431	169	30	journal	journal	NOUN
cana-431	169	31	of	of	ADP
cana-431	169	32	statistics	statistics	PROPN
cana-431	169	33	&	&	CCONJ
cana-431	169	34	management	management	NOUN
cana-431	169	35	systems	system	NOUN
cana-431	169	36	.	.	PUNCT
cana-431	170	1	[	[	X
cana-431	170	2	14	14	NUM
cana-431	170	3	]	]	X
cana-431	170	4	annette	annette	PROPN
cana-431	170	5	j.	j.	PROPN
cana-431	170	6	dobson	dobson	PROPN
cana-431	170	7	“	"	PUNCT
cana-431	170	8	mathematical	mathematical	ADJ
cana-431	170	9	models	model	NOUN
cana-431	170	10	in	in	ADP
cana-431	170	11	the	the	DET
cana-431	170	12	social	social	ADJ
cana-431	170	13	and	and	CCONJ
cana-431	170	14	behavioural	behavioural	ADJ
cana-431	170	15	sciences	science	NOUN
cana-431	170	16	”	"	PUNCT
cana-431	171	1	[	[	X
cana-431	171	2	15	15	NUM
cana-431	171	3	]	]	PUNCT
cana-431	171	4	a.	a.	NOUN
cana-431	171	5	c.	c.	PROPN
cana-431	171	6	flowler	flowler	PROPN
cana-431	171	7	“	"	PUNCT
cana-431	171	8	mathematical	mathematical	ADJ
cana-431	171	9	models	model	NOUN
cana-431	171	10	in	in	ADP
cana-431	171	11	applied	applied	ADJ
cana-431	171	12	sciences	science	NOUN
cana-431	171	13	”	"	PUNCT
cana-431	171	14	.	.	PUNCT
cana-431	172	1	[	[	X
cana-431	172	2	16	16	NUM
cana-431	172	3	]	]	PUNCT
cana-431	172	4	purnami	purnami	NOUN
cana-431	172	5	widyaningsih	widyaningsih	NOUN
cana-431	172	6	,	,	PUNCT
cana-431	172	7	rifqi	rifqi	PROPN
cana-431	172	8	choiril	choiril	PROPN
cana-431	172	9	affan	affan	PROPN
cana-431	172	10	,	,	PUNCT
cana-431	172	11	dewi	dewi	PROPN
cana-431	172	12	reno	reno	PROPN
cana-431	172	13	sari	sari	PROPN
cana-431	172	14	saputro	saputro	VERB
cana-431	172	15	“	"	PUNCT
cana-431	172	16	a	a	DET
cana-431	172	17	mathematical	mathematical	ADJ
cana-431	172	18	model	model	NOUN
cana-431	172	19	for	for	ADP
cana-431	172	20	the	the	DET
cana-431	172	21	epidemiology	epidemiology	NOUN
cana-431	172	22	of	of	ADP
cana-431	172	23	diabetes	diabetes	NOUN
cana-431	172	24	mellitus	mellitus	NOUN
cana-431	172	25	with	with	ADP
cana-431	172	26	lifestyle	lifestyle	NOUN
cana-431	172	27	and	and	CCONJ
cana-431	172	28	genetic	genetic	ADJ
cana-431	172	29	factors”,2018	factors”,2018	NOUN
cana-431	172	30	,	,	PUNCT
cana-431	172	31	iop	iop	NOUN
cana-431	172	32	publishing	publishing	NOUN
cana-431	172	33	.	.	PUNCT