id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
mkg-10366	Shabrina, Zhafira Nur; Sumarta, Ni Putu Mira; Pramono, Coen	A study of cytotoxicity and proliferation of Cosmos caudatus Kunth leaf extract in human gingival fibroblast culture	2018	6	.pdf	application/pdf	3712	216	49	The study was carried out following a drug development sequence which comprised of in vitro examination, animal experiments (in vivo), clinical trials and preparation for marketing.9 Cell culture was obtained from human gingival cells because these could be cultured into primary cell line culture demonstrating a similar pattern of behavior to in vivo reactions compared to cell lines.13 Cell lines have been used for decades to produce culture, resulting in stronger cells often genetically and phenotypically different from their original networks which underwent morphological changes. This concentration was suitable for fibroblast cell proliferation compared to those below 600 μg/ml because, according to the dose-response relationship, weaker extract concentrations will produce a lower number of living fibroblasts or will fail to produce optimum results.	cache/mkg-10366.pdf	txt/mkg-10366.txt