id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
mkg-1053	Syafriadi, Mei; Saku, Takashi	p53-protein over-expression and gene mutational of oral carcinoma in-situ	2007	6	.pdf	application/pdf	4385	191	52	Mutational analysis for p53 gene showed 43% of total cases of CIS had p53 gene mutation therefore CIS-basaloid type had mutations more frequently than the other types and mutation in exon 8 more dominant than other exons, which had some common mutation at codons 196, 248, 282, 291, and 306, while no particular mutations were found in control (SED).Our criteria to diagnose several types of oral carcinoma in-situ by p53 protein expression and mutational analysis could be used to understand molecular behavior of CIS. Several cases showed no p53 protein immunopositivities, because p53 gene mutation had stop codons mutation, and the antibody could not detect p53 protein expression because protein had not been produced yet.	cache/mkg-1053.pdf	txt/mkg-1053.txt