id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
mkg-1066	Hasibuan, Sayuti	Effect of combination antiretroviral therapy on the frequency of oral candidiasis in HIV/AIDS patient	2007	4	.pdf	application/pdf	2713	154	42	Oral candidiasis are reported to have an increased prevalence among patients with HIV-infected or AIDS and has been used as diagnostic and prognostic markers for the disease.6,7,8 The introduction of combination therapies, called HAART as a treatment for HIV-infected patients in the mid-1990s, however has been accompanied by multiple report of reduction in the incidence and prevalence of oral mucosal diseases including oral candidiasis.6 For instance, Patton et al from United States (1995–1999) have reported significant decrease in the prevalence of oral candidiasis from 20.3% to 16.7%.9 The frequency of Candida isolation and clinical signs of oral candidiasis increases with advancing HIV infection.10,11 The prevalence ranges between 30 and 60% among HIV-infected subjects and reaches 90% in patients with AIDS.12,13 Oral candidiasis in HIV-infected and AIDS patients may present as pseudomembranous, erythematous, hyperplastic and angular cheilitis variants.10,11,12 The presence of oral candidiasis in HIV-infected and AIDS patients was associated with a number factors including low CD4 counts, increased viral load, xerostomia, age and Secretory aspartyl proteinase (Sap), extracellular hydrolytic enzyme was product by Candida.7,10,13,14 Oral candidiasis occurs more frequently in HIV- infected patients with low CD4 counts.	cache/mkg-1066.pdf	txt/mkg-1066.txt