id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
mkg-12856	Hendrijantini, Nike	Comparative in vitro study of the cytotoxicity of gelatine and alginate to human umbilical cord mesenchymal stem cells	2019	5	.pdf	application/pdf	3519	214	51	E-mail: nike-h@fkg.unair.ac.id INTRODUCTION Stem cell research has increased due to the realisation that stem cell-based therapies have the potential to repair bone or tooth loss caused by trauma, fractures, surgery, tumour resection, congenital malformation, dental implant failure- associated osteoporosis and periodontitis in dentistry.1 Tissue construction which consists of stem cells and scaffold combination represents a promising approach to bone tissue engineering. Although human bone marrow mesenchymal stem cells (hBM-MSCs) are the most common and best characterized stem cell source, umbilical cord derived stem cells (hUC- MSCs) provide a novel source of MSCs3 and, recently, hUC- MSCs have been shown to possess significant osteogenic differentiation potential.4 Isolation of hBM-MSCs requires an invasive procedure that may cause aspiration site morbidity, while hUC-MSCs are easily obtained through a non-invasive process that does not result in morbidity.5 Moreover, hUC- MSCs can be less immunogenic than hBM-MSCs.3 The ideal scaffold is able to facilitate adhesion, migration, proliferation and cellular organization in three-dimensional fashion from a cell population required for tissue engineering.	cache/mkg-12856.pdf	txt/mkg-12856.txt