id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
mkg-17737	Andriani, Ika; Meiyanto, Edy; Suryono, S.; Ana, Ika Dewi	The combination of carbonate hydroxyapatite and human β-defensin 3 to enhance collagen fibre density in periodontitis Sprague Dawley rats	2020	5	.pdf	application/pdf	3504	202	50	Based on previous studies, the biological activity of synthetic CHA is better than synthetic hydroxyapatite because the incorporation of carbonates in hydroxyapatite causes an increase in solubility and decreases crystallisation.6 CHA bone grafts can also be combined with various antibiotics, for example, metronidazole.8 The use of local and systemic antimicrobial therapy in extensive periodontal treatment is important as adjunctive therapy to prevent the growth and development of pathogenic bacteria.9 Human β-defensin3 (HBD3) is an antimicrobial cationic peptide with an immunomodulatory effect on innate and adaptive immune responses. J. (Majalah Kedokteran Gigi) 2020 June; 53(2): 76–80 graft that promotes bone tissue without fibrotic tissue formation and stimulates osteogenesis.6,7	cache/mkg-17737.pdf	txt/mkg-17737.txt