id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
mkg-761	Parisihni, Kristanti; Revianti, Syamsulina	Antifungal effect of Sticophus hermanii and Holothuria atra extract and its cytotoxicity on gingiva-derived mesenchymal stem cell	2013	6	.pdf	application/pdf	4470	212	44	Mitrano TI, Grob MS, Carrión F, Nova-Lamperti E, Luz PA, Fierro FS,Quintero A, Chaparro A, Sanz A. Culture and characterization of mesenchymal stem cells from human gingival tissue. Considering to the bioactive compound, the extract of Sticophus hermanii and Holothuria atra are potentially explored its antifungal property to Candida albicans and as the potential candidatetherapeutic agent in oral candidiasis,8,14 its cytotoxicity should be well identified to assure the biocompatibility to oral cells.15 During the last years, the interest of in vitro systems as an alternative to animal experiments in toxicological research has been steadily increasing.16–18 Stem cells and their derivatives represent a promising opportunity for developing in vitro, human cell assays that would ultimately replace, enhance, or surpass the current models that are used for predictive toxicology.19–23 In this paper, two sea cucumber extract Sticophus hermanii and Holothuria atra were studied its antifungal property to Candida albicans and its cytotoxicity to gingiva-derived mesenchymal stem cell.	cache/mkg-761.pdf	txt/mkg-761.txt