id	sid	eid	entity	type
mkg-795	1	1	46	CARDINAL
mkg-795	1	2	1	CARDINAL
mkg-795	1	3	iwa sutardjo	PERSON
mkg-795	1	4	sudarso2 1department	FAC
mkg-795	1	5	2department	CARDINAL
mkg-795	2	1	universitas gadjah	ORG
mkg-795	2	2	mada	GPE
mkg-795	2	3	yogyakarta	GPE
mkg-795	3	1	indonesia	GPE
mkg-795	7	1	one	CARDINAL
mkg-795	9	1	p45skp2	GPE
mkg-795	12	1	boyden chamber kit	ORG
mkg-795	12	2	mtt	ORG
mkg-795	13	1	p45skp2	GPE
mkg-795	15	1	p45skp2	GPE
mkg-795	16	1	p45skp2	GPE
mkg-795	17	1	p45skp2	GPE
mkg-795	17	2	abstrak	GPE
mkg-795	17	3	mempunyai karakteristik invasi	PERSON
mkg-795	18	1	dan metastasis ke	PERSON
mkg-795	18	2	yang tinggi	PERSON
mkg-795	19	1	pilihan perawatan kanker tersebut masih sangat terbatas	ORG
mkg-795	20	1	walaupun demikian	PERSON
mkg-795	20	2	strategi baru untuk penanganan kanker yaitu terapi gen menjadi pilihan utama	ORG
mkg-795	21	1	gen p45skp2 sebagai	PERSON
mkg-795	21	2	salah satu	ORG
mkg-795	21	3	terapi kanker	PERSON
mkg-795	22	1	untuk menghambat	PERSON
mkg-795	22	2	aktivitas	NORP
mkg-795	22	3	dilakukan rekayasa	GPE
mkg-795	23	1	tujuan	PERSON
mkg-795	23	2	menguji aktivitas	PERSON
mkg-795	23	3	p45skp2	GPE
mkg-795	24	1	metode	PERSON
mkg-795	24	2	jenis penelitian	ORG
mkg-795	24	3	yang digunakan adalah	PERSON
mkg-795	24	4	murni dengan rancangan	PERSON
mkg-795	25	1	induksi	ORG
mkg-795	25	2	sel yang ditransfeksi	ORG
mkg-795	25	3	p45skp2	GPE
mkg-795	25	4	dievaluasi menggunakan uji	ORG
mkg-795	25	5	kolorimetrik dan	PERSON
mkg-795	26	1	mendeteksi hambatan	GPE
mkg-795	26	2	dan pertumbuhan sel	PERSON
mkg-795	27	1	yang ditransfeksi	PERSON
mkg-795	27	2	p45skp2	GPE
mkg-795	27	3	dilakukan uji boyden	ORG
mkg-795	27	4	dan uji mtt	PERSON
mkg-795	28	1	hasil	PERSON
mkg-795	30	1	yang ditransfeksi	PERSON
mkg-795	30	2	p45skp2	GPE
mkg-795	30	3	menurun secara signifikan dibandingkan dengan	ORG
mkg-795	30	4	p45skp2	GPE
mkg-795	31	1	p45skp2	GPE
mkg-795	31	2	dengan meningkatkan aktivitas	PERSON
mkg-795	31	3	dan	PERSON
mkg-795	32	1	hambatan	GPE
mkg-795	32	2	dan pertumbuhan sel	PERSON
mkg-795	33	1	secara signifikan meningkat pada sel yang diperlakukan dengan p45skp2	PERSON
mkg-795	34	1	kesimpulan	PERSON
mkg-795	35	1	p45skp2	GPE
mkg-795	35	2	aktivitas	NORP
mkg-795	35	3	yang kuat	PERSON
mkg-795	36	1	dari molekul	PERSON
mkg-795	36	2	tersebut dapat menjanjikan suatu	ORG
mkg-795	36	3	untuk jenis kanker palatum tersebut	PERSON
mkg-795	37	1	gen p45skp2	PERSON
mkg-795	37	2	sel kanker palatum lunak research	ORG
mkg-795	38	1	approximately 2%	PERCENT
mkg-795	39	1	the past several decades	DATE
mkg-795	40	1	1980	DATE
mkg-795	40	2	1990	DATE
mkg-795	40	3	48%	PERCENT
mkg-795	40	4	47%	PERCENT
mkg-795	40	5	the past 10 years	DATE
mkg-795	42	1	p45 s-phase	PERSON
mkg-795	42	2	2	CARDINAL
mkg-795	42	3	skp2	NORP
mkg-795	42	4	scfskp2	PRODUCT
mkg-795	42	5	skp2	NORP
mkg-795	42	6	cyclin	GPE
mkg-795	42	7	cdk	ORG
mkg-795	42	8	g1	ORG
mkg-795	42	9	skp2	NORP
mkg-795	42	10	g1	ORG
mkg-795	43	1	skp2	LOC
mkg-795	44	1	skp2	NORP
mkg-795	44	2	cancers.10	GPE
mkg-795	44	3	skp2	NORP
mkg-795	44	4	skp2	NORP
mkg-795	45	1	p45skp2	GPE
mkg-795	49	1	p45skp2	GPE
mkg-795	50	1	10%	PERCENT
mkg-795	50	2	fcs	GPE
mkg-795	50	3	moregate biotech	ORG
mkg-795	50	4	australia	GPE
mkg-795	50	5	100 mg	QUANTITY
mkg-795	50	6	100	CARDINAL
mkg-795	50	7	invitrogen corp.	ORG
mkg-795	50	8	carlsbad	GPE
mkg-795	51	1	95%	PERCENT
mkg-795	51	2	5%	PERCENT
mkg-795	51	3	37°	QUANTITY
mkg-795	51	4	two	CARDINAL
mkg-795	52	1	two	CARDINAL
mkg-795	52	2	5’-tcctgtgcatagcgtccgcaggccc	CARDINAL
mkg-795	52	3	3	CARDINAL
mkg-795	52	4	skp2	NORP
mkg-795	52	5	15 to 40	CARDINAL
mkg-795	52	6	5’-cccggacgcctgcgatacgtgtcct-3	CARDINAL
mkg-795	53	1	germany	GPE
mkg-795	55	1	100 mm dish	QUANTITY
mkg-795	55	2	falcon	ORG
mkg-795	55	3	becton dickinson labware	PERSON
mkg-795	55	4	lincoln park	ORG
mkg-795	55	5	nj, usa	ORG
mkg-795	55	6	2x105	CARDINAL
mkg-795	55	7	10%	PERCENT
mkg-795	55	8	fcs	GPE
mkg-795	56	1	72 hours	TIME
mkg-795	57	1	5 ml	QUANTITY
mkg-795	57	2	500 ml	QUANTITY
mkg-795	58	1	coulter	GPE
mkg-795	58	2	miami	GPE
mkg-795	58	3	fl, usa	ORG
mkg-795	61	1	405	CARDINAL
mkg-795	62	1	2 hours	TIME
mkg-795	62	2	37°	QUANTITY
mkg-795	62	3	405	CARDINAL
mkg-795	62	4	bio-rad laboratories	ORG
mkg-795	62	5	hercules	GPE
mkg-795	64	1	96	CARDINAL
mkg-795	64	2	falcon	ORG
mkg-795	64	3	nj, usa	ORG
mkg-795	64	4	5	CARDINAL
mkg-795	64	5	103	CARDINAL
mkg-795	64	6	10%	PERCENT
mkg-795	64	7	fcs	GPE
mkg-795	64	8	the day	DATE
mkg-795	65	1	100 mm	QUANTITY
mkg-795	66	1	24 and 48 hours	TIME
mkg-795	66	2	mtt	ORG
mkg-795	66	3	3-(4,5	CARDINAL
mkg-795	66	4	supriatno	PERSON
mkg-795	66	5	penyakit mulut	PERSON
mkg-795	66	6	fakultas	GPE
mkg-795	66	7	kedokteran gigi universitas	PERSON
mkg-795	66	8	mada	GPE
mkg-795	68	1	yogyakarta 55281	GPE
mkg-795	68	2	indonesia	GPE
mkg-795	71	1	j. (maj	PERSON
mkg-795	72	1	gigi	PERSON
mkg-795	72	2	46	CARDINAL
mkg-795	72	3	1	CARDINAL
mkg-795	72	4	2013	DATE
mkg-795	72	5	18–22	CARDINAL
mkg-795	73	1	5	CARDINAL
mkg-795	73	2	105	CARDINAL
mkg-795	73	3	50 ml	QUANTITY
mkg-795	74	1	24 hours	TIME
mkg-795	74	2	two	CARDINAL
mkg-795	74	3	40x	CARDINAL
mkg-795	75	1	4.5	CARDINAL
mkg-795	75	2	abacus concepts	ORG
mkg-795	75	3	berkeley	GPE
mkg-795	76	1	5%	PERCENT
mkg-795	78	1	33.5%	PERCENT
mkg-795	78	2	hi-skp2	NORP
mkg-795	78	3	18.8%	PERCENT
mkg-795	79	1	17.6%	PERCENT
mkg-795	79	2	1	CARDINAL
mkg-795	81	1	48 hours	TIME
mkg-795	82	1	2	CARDINAL
mkg-795	82	2	1.75 fold	CARDINAL
mkg-795	82	3	hi-skp2	NORP
mkg-795	83	1	skp2	LOC
mkg-795	83	2	at least 1.75	CARDINAL
mkg-795	83	3	skp2	NORP
mkg-795	83	4	mtt	ORG
mkg-795	83	5	24 and 48 hours	TIME
mkg-795	84	1	skp2	NORP
mkg-795	84	2	3	CARDINAL
mkg-795	85	1	skp2	NORP
mkg-795	85	2	skp2	NORP
mkg-795	85	3	boyden chamber kit	ORG
mkg-795	85	4	24 hours	TIME
mkg-795	86	1	4	CARDINAL
mkg-795	86	2	skp2	NORP
mkg-795	86	3	hi-skp2	NORP
mkg-795	87	1	skp2	NORP
mkg-795	87	2	skp2	NORP
mkg-795	87	3	18.8%	PERCENT
mkg-795	87	4	10.9%	PERCENT
mkg-795	87	5	33.5%	PERCENT
mkg-795	87	6	17.6%	PERCENT
mkg-795	87	7	1	CARDINAL
mkg-795	88	1	skp2	NORP
mkg-795	88	2	skp2	NORP
mkg-795	88	3	2	CARDINAL
mkg-795	90	1	0.3 0.6 0.9	QUANTITY
mkg-795	90	2	24 hours	TIME
mkg-795	90	3	48 hours	TIME
mkg-795	90	4	skp2	NORP
mkg-795	90	5	skp2	NORP
mkg-795	90	6	540	CARDINAL
mkg-795	90	7	3	CARDINAL
mkg-795	91	1	24 and 48 hours	TIME
mkg-795	92	1	120	CARDINAL
mkg-795	92	2	skp2	NORP
mkg-795	92	3	4	CARDINAL
mkg-795	93	1	24 hours	TIME
mkg-795	94	1	p45skp2	GPE
mkg-795	94	2	skp2	NORP
mkg-795	94	3	this decade	DATE
mkg-795	97	1	sideeffects	PRODUCT
mkg-795	99	1	skp2	NORP
mkg-795	100	1	skp2	NORP
mkg-795	101	1	skp2	NORP
mkg-795	106	1	one	CARDINAL
mkg-795	106	2	bcl-2	PERSON
mkg-795	110	1	diseases.17	GPE
mkg-795	110	2	hi-skp2	NORP
mkg-795	111	1	skp2	NORP
mkg-795	112	1	skp2	NORP
mkg-795	112	2	skp2	NORP
mkg-795	112	3	skp2	NORP
mkg-795	112	4	jab1	PERSON
mkg-795	112	5	p27kip1 protein.13	ORG
mkg-795	112	6	skp2	NORP
mkg-795	113	1	p45skp2	GPE
mkg-795	115	1	mitsunobu	NORP
mkg-795	115	2	sato dds	PERSON
mkg-795	115	3	ph.d	ORG
mkg-795	115	4	koji harada	PERSON
mkg-795	115	5	dds.	PERSON
mkg-795	115	6	ph.d	ORG
mkg-795	115	7	hamakawa dds	PERSON
mkg-795	115	8	ph.d	ORG
mkg-795	115	9	tokushima university	ORG
mkg-795	115	10	japan	GPE
mkg-795	116	1	1	CARDINAL
mkg-795	116	2	cohan dm	PERSON
mkg-795	116	3	kaplan se	ORG
mkg-795	116	4	rigual n	PERSON
mkg-795	116	5	loree t	PERSON
mkg-795	116	6	hicks wl jr.	PERSON
mkg-795	117	1	curr opin	PERSON
mkg-795	117	2	surg 2009	DATE
mkg-795	117	3	17(2	DATE
mkg-795	117	4	88–94	CARDINAL
mkg-795	118	1	2	CARDINAL
mkg-795	118	2	ammar	PERSON
mkg-795	118	3	begum	PERSON
mkg-795	118	4	iga h	ORG
mkg-795	118	5	yoshida h	ORG
mkg-795	118	6	sato m.	PERSON
mkg-795	118	7	cxcr4	PRODUCT
mkg-795	119	1	oncol 2004	DATE
mkg-795	119	2	65–71	CARDINAL
mkg-795	120	1	3	CARDINAL
mkg-795	120	2	inagi k	PERSON
mkg-795	120	3	nakayama m	PERSON
mkg-795	120	4	nagai h.	PERSON
mkg-795	121	1	suppl 2002	DATE
mkg-795	121	2	547	CARDINAL
mkg-795	122	1	25–9	CARDINAL
mkg-795	122	2	4	CARDINAL
mkg-795	122	3	bray f	PERSON
mkg-795	122	4	sankila	PERSON
mkg-795	122	5	europe	LOC
mkg-795	122	6	1995	DATE
mkg-795	123	1	europ	ORG
mkg-795	123	2	2002	DATE
mkg-795	123	3	38(1	CARDINAL
mkg-795	123	4	99–166	DATE
mkg-795	124	1	j.	PERSON
mkg-795	125	1	gigi	PERSON
mkg-795	126	1	46	CARDINAL
mkg-795	126	2	1	CARDINAL
mkg-795	126	3	18–22 5	DATE
mkg-795	127	1	wu l	PERSON
mkg-795	127	2	grigoryan av	PERSON
mkg-795	127	3	li y	PERSON
mkg-795	127	4	hao b	PERSON
mkg-795	127	5	pagano m	PERSON
mkg-795	127	6	cardozo tj	PERSON
mkg-795	127	7	skp2	NORP
mkg-795	128	1	2012	DATE
mkg-795	128	2	1515–24	CARDINAL
mkg-795	129	1	zheng wq	PERSON
mkg-795	129	2	zheng jm	PERSON
mkg-795	129	3	ma r	PERSON
mkg-795	129	4	meng	PERSON
mkg-795	129	5	ni cr	PERSON
mkg-795	129	6	skp2	NORP
mkg-795	129	7	skp2	LOC
mkg-795	130	1	2005	DATE
mkg-795	130	2	70(11	DATE
mkg-795	131	1	bornstein g	PERSON
mkg-795	131	2	ben	PERSON
mkg-795	131	3	krausz mm	PERSON
mkg-795	131	4	hershko a.	PERSON
mkg-795	131	5	p27kip1	PRODUCT
mkg-795	131	6	skp2	NORP
mkg-795	132	1	2001	DATE
mkg-795	132	2	91(9	CARDINAL
mkg-795	132	3	8	CARDINAL
mkg-795	133	1	chiarle	PERSON
mkg-795	133	2	de wolf-peeters	PERSON
mkg-795	133	3	inghirami g. s	PERSON
mkg-795	133	4	2	CARDINAL
mkg-795	134	1	j pathol	PERSON
mkg-795	134	2	2002	DATE
mkg-795	134	3	160(4	CARDINAL
mkg-795	134	4	1457–66	CARDINAL
mkg-795	135	1	masuda ta	PERSON
mkg-795	135	2	inoue h	PERSON
mkg-795	135	3	yoshikawa y	PERSON
mkg-795	135	4	nakayama k	PERSON
mkg-795	135	5	mori m.	PERSON
mkg-795	135	6	2	CARDINAL
mkg-795	135	7	skp2	NORP
mkg-795	135	8	skp2	NORP
mkg-795	136	1	2002	DATE
mkg-795	136	2	62	CARDINAL
mkg-795	136	3	3819–25	CARDINAL
mkg-795	137	1	10	CARDINAL
mkg-795	138	1	yokoi s	PERSON
mkg-795	138	2	yasui k	PERSON
mkg-795	138	3	lizasa	GPE
mkg-795	138	4	takahashi t	GPE
mkg-795	138	5	fujisawa	ORG
mkg-795	138	6	inazawa j. down-regulation	PERSON
mkg-795	138	7	skp2	NORP
mkg-795	139	1	sci 2003	ORG
mkg-795	139	2	94(4	CARDINAL
mkg-795	140	1	11	CARDINAL
mkg-795	141	1	nakayama k	PERSON
mkg-795	141	2	nagahama h	PERSON
mkg-795	141	3	minamishima ya	PERSON
mkg-795	141	4	matsumoto m	PERSON
mkg-795	141	5	nakamichi	PERSON
mkg-795	141	6	kitagawa k.	PERSON
mkg-795	141	7	skp2	NORP
mkg-795	141	8	p27kip1	PERSON
mkg-795	142	1	j 2000	PERSON
mkg-795	142	2	2069–81	CARDINAL
mkg-795	143	1	12	CARDINAL
mkg-795	144	1	supriatno	PERSON
mkg-795	145	1	oligonukleotid	PERSON
mkg-795	145	2	skp2	NORP
mkg-795	146	1	mada university of inter-cluster	ORG
mkg-795	147	1	57th	ORDINAL
mkg-795	147	2	natalis gmu	PERSON
mkg-795	147	3	november 28	DATE
mkg-795	147	4	yogyakarta	GPE
mkg-795	147	5	2006	DATE
mkg-795	148	1	1–13	CARDINAL
mkg-795	149	1	13	CARDINAL
mkg-795	150	1	supriatno	PERSON
mkg-795	150	2	harada k	PERSON
mkg-795	150	3	sato m.	PERSON
mkg-795	151	1	oncol 2005	DATE
mkg-795	151	2	627–35	DATE
mkg-795	152	1	14	CARDINAL
mkg-795	152	2	wacheck v	PERSON
mkg-795	152	3	weiss	ORG
mkg-795	154	1	2006	DATE
mkg-795	154	2	59(1	CARDINAL
mkg-795	154	3	65–73	CARDINAL
mkg-795	155	1	15	CARDINAL
mkg-795	155	2	stuart d	ORG
mkg-795	155	3	allen	PERSON
mkg-795	156	1	j contr rel	PERSON
mkg-795	156	2	2001	DATE
mkg-795	156	3	74(1	CARDINAL
mkg-795	156	4	69–75	CARDINAL
mkg-795	157	1	16	CARDINAL
mkg-795	158	1	azuma m	ORG
mkg-795	158	2	harada k	PERSON
mkg-795	158	3	motegi k	PERSON
mkg-795	158	4	ashida y	PERSON
mkg-795	158	5	sato m. potentiation	PERSON
mkg-795	158	6	5-fluorouracil	QUANTITY
mkg-795	159	1	oncol 2004	DATE
mkg-795	159	2	24(6	DATE
mkg-795	159	3	1449–55	DATE
mkg-795	160	1	17	DATE
mkg-795	160	2	qiao l	PERSON
mkg-795	160	3	wong bcw	PERSON
mkg-795	161	1	2009	DATE
mkg-795	161	2	12(3	CARDINAL
mkg-795	161	3	55–64	CARDINAL