id	sid	tid	token	lemma	pos
mkg-56898	1	1	367367	367367	NUM
mkg-56898	1	2	dental	dental	ADJ
mkg-56898	1	3	journal	journal	NOUN
mkg-56898	1	4	(	(	PUNCT
mkg-56898	1	5	majalah	majalah	PROPN
mkg-56898	1	6	kedokteran	kedokteran	PROPN
mkg-56898	1	7	gigi	gigi	PROPN
mkg-56898	1	8	)	)	PUNCT
mkg-56898	1	9	2025	2025	NUM
mkg-56898	1	10	december	december	NOUN
mkg-56898	1	11	;	;	PUNCT
mkg-56898	1	12	58(4	58(4	NUM
mkg-56898	1	13	):	):	PUNCT
mkg-56898	1	14	367–375	367–375	NUM
mkg-56898	1	15	original	original	ADJ
mkg-56898	1	16	article	article	NOUN
mkg-56898	1	17	confirmation	confirmation	NOUN
mkg-56898	1	18	of	of	ADP
mkg-56898	1	19	the	the	DET
mkg-56898	1	20	potential	potential	ADJ
mkg-56898	1	21	mechanism	mechanism	NOUN
mkg-56898	1	22	of	of	ADP
mkg-56898	1	23	pentagamavunon-0	pentagamavunon-0	X
mkg-56898	1	24	against	against	ADP
mkg-56898	1	25	temporomandibular	temporomandibular	ADJ
mkg-56898	1	26	arthritis	arthritis	NOUN
mkg-56898	1	27	using	use	VERB
mkg-56898	1	28	bioinformatic	bioinformatic	ADJ
mkg-56898	1	29	approaches	approach	NOUN
mkg-56898	1	30	dwi	dwi	PROPN
mkg-56898	1	31	merry	merry	PROPN
mkg-56898	1	32	christmarini	christmarini	PROPN
mkg-56898	1	33	robin1	robin1	PROPN
mkg-56898	1	34	,	,	PUNCT
mkg-56898	1	35	retno	retno	PROPN
mkg-56898	1	36	ardhani2	ardhani2	PROPN
mkg-56898	1	37	,	,	PUNCT
mkg-56898	1	38	dhania	dhania	PROPN
mkg-56898	1	39	novitasari3	novitasari3	PROPN
mkg-56898	1	40	,	,	PUNCT
mkg-56898	1	41	banun	banun	PROPN
mkg-56898	1	42	kusumawardani4	kusumawardani4	PROPN
mkg-56898	1	43	,	,	PUNCT
mkg-56898	1	44	faaza	faaza	PROPN
mkg-56898	1	45	aulia	aulia	PROPN
mkg-56898	1	46	rahman5	rahman5	PROPN
mkg-56898	1	47	,	,	PUNCT
mkg-56898	1	48	edy	edy	PROPN
mkg-56898	1	49	meiyanto5,6	meiyanto5,6	PROPN
mkg-56898	1	50	,	,	PUNCT
mkg-56898	1	51	nunuk	nunuk	VERB
mkg-56898	1	52	purwanti1,2	purwanti1,2	PROPN
mkg-56898	1	53	1doctoral	1doctoral	NUM
mkg-56898	1	54	study	study	NOUN
mkg-56898	1	55	program	program	NOUN
mkg-56898	1	56	of	of	ADP
mkg-56898	1	57	dentistry	dentistry	NOUN
mkg-56898	1	58	,	,	PUNCT
mkg-56898	1	59	faculty	faculty	NOUN
mkg-56898	1	60	of	of	ADP
mkg-56898	1	61	dentistry	dentistry	NOUN
mkg-56898	1	62	,	,	PUNCT
mkg-56898	1	63	universitas	universita	NOUN
mkg-56898	1	64	gadjah	gadjah	PROPN
mkg-56898	1	65	mada	mada	PROPN
mkg-56898	1	66	,	,	PUNCT
mkg-56898	1	67	sleman	sleman	NOUN
mkg-56898	1	68	,	,	PUNCT
mkg-56898	1	69	yogyakarta	yogyakarta	PROPN
mkg-56898	1	70	,	,	PUNCT
mkg-56898	1	71	indonesia	indonesia	PROPN
mkg-56898	1	72	2department	2department	NUM
mkg-56898	1	73	of	of	ADP
mkg-56898	1	74	dental	dental	ADJ
mkg-56898	1	75	biomedical	biomedical	ADJ
mkg-56898	1	76	sciences	science	NOUN
mkg-56898	1	77	,	,	PUNCT
mkg-56898	1	78	faculty	faculty	NOUN
mkg-56898	1	79	of	of	ADP
mkg-56898	1	80	dentistry	dentistry	NOUN
mkg-56898	1	81	,	,	PUNCT
mkg-56898	1	82	universitas	universita	NOUN
mkg-56898	1	83	gadjah	gadjah	PROPN
mkg-56898	1	84	mada	mada	PROPN
mkg-56898	1	85	,	,	PUNCT
mkg-56898	1	86	sleman	sleman	NOUN
mkg-56898	1	87	,	,	PUNCT
mkg-56898	1	88	yogyakarta	yogyakarta	PROPN
mkg-56898	1	89	,	,	PUNCT
mkg-56898	1	90	indonesia	indonesia	PROPN
mkg-56898	1	91	3department	3department	NUM
mkg-56898	1	92	of	of	ADP
mkg-56898	1	93	pharmaceutical	pharmaceutical	ADJ
mkg-56898	1	94	analysis	analysis	NOUN
mkg-56898	1	95	and	and	CCONJ
mkg-56898	1	96	medicinal	medicinal	ADJ
mkg-56898	1	97	chemistry	chemistry	NOUN
mkg-56898	1	98	,	,	PUNCT
mkg-56898	1	99	faculty	faculty	NOUN
mkg-56898	1	100	of	of	ADP
mkg-56898	1	101	pharmacy	pharmacy	NOUN
mkg-56898	1	102	,	,	PUNCT
mkg-56898	1	103	universitas	universita	NOUN
mkg-56898	1	104	padjajaran	padjajaran	ADJ
mkg-56898	1	105	,	,	PUNCT
mkg-56898	1	106	bandung	bandung	PROPN
mkg-56898	1	107	,	,	PUNCT
mkg-56898	1	108	indonesia	indonesia	PROPN
mkg-56898	1	109	4department	4department	NUM
mkg-56898	1	110	of	of	ADP
mkg-56898	1	111	biomedical	biomedical	ADJ
mkg-56898	1	112	sciences	science	NOUN
mkg-56898	1	113	,	,	PUNCT
mkg-56898	1	114	faculty	faculty	NOUN
mkg-56898	1	115	of	of	ADP
mkg-56898	1	116	dentistry	dentistry	NOUN
mkg-56898	1	117	,	,	PUNCT
mkg-56898	1	118	universitas	universita	NOUN
mkg-56898	1	119	jember	jember	PROPN
mkg-56898	1	120	,	,	PUNCT
mkg-56898	1	121	jember	jember	PROPN
mkg-56898	1	122	,	,	PUNCT
mkg-56898	1	123	indonesia	indonesia	PROPN
mkg-56898	1	124	5cancer	5cancer	NUM
mkg-56898	1	125	chemoprevention	chemoprevention	NOUN
mkg-56898	1	126	research	research	NOUN
mkg-56898	1	127	center	center	NOUN
mkg-56898	1	128	,	,	PUNCT
mkg-56898	1	129	faculty	faculty	NOUN
mkg-56898	1	130	of	of	ADP
mkg-56898	1	131	pharmacy	pharmacy	NOUN
mkg-56898	1	132	,	,	PUNCT
mkg-56898	1	133	universitas	universita	NOUN
mkg-56898	1	134	gadjah	gadjah	PROPN
mkg-56898	1	135	mada	mada	PROPN
mkg-56898	1	136	,	,	PUNCT
mkg-56898	1	137	sleman	sleman	NOUN
mkg-56898	1	138	,	,	PUNCT
mkg-56898	1	139	yogyakarta	yogyakarta	PROPN
mkg-56898	1	140	,	,	PUNCT
mkg-56898	1	141	indonesia	indonesia	PROPN
mkg-56898	1	142	6department	6department	NUM
mkg-56898	1	143	of	of	ADP
mkg-56898	1	144	pharmaceutical	pharmaceutical	ADJ
mkg-56898	1	145	chemistry	chemistry	NOUN
mkg-56898	1	146	,	,	PUNCT
mkg-56898	1	147	faculty	faculty	NOUN
mkg-56898	1	148	of	of	ADP
mkg-56898	1	149	pharmacy	pharmacy	NOUN
mkg-56898	1	150	,	,	PUNCT
mkg-56898	1	151	universitas	universita	NOUN
mkg-56898	1	152	gadjah	gadjah	PROPN
mkg-56898	1	153	mada	mada	PROPN
mkg-56898	1	154	,	,	PUNCT
mkg-56898	1	155	sleman	sleman	NOUN
mkg-56898	1	156	,	,	PUNCT
mkg-56898	1	157	yogyakarta	yogyakarta	PROPN
mkg-56898	1	158	,	,	PUNCT
mkg-56898	1	159	indonesia	indonesia	PROPN
mkg-56898	1	160	abstract	abstract	ADJ
mkg-56898	1	161	background	background	NOUN
mkg-56898	1	162	:	:	PUNCT
mkg-56898	1	163	non	non	ADJ
mkg-56898	1	164	-	-	ADJ
mkg-56898	1	165	steroidal	steroidal	ADJ
mkg-56898	1	166	anti	anti	ADJ
mkg-56898	1	167	-	-	ADJ
mkg-56898	1	168	inflammatory	inflammatory	ADJ
mkg-56898	1	169	drugs	drug	NOUN
mkg-56898	1	170	(	(	PUNCT
mkg-56898	1	171	nsaid	nsaid	PROPN
mkg-56898	1	172	)	)	PUNCT
mkg-56898	1	173	are	be	AUX
mkg-56898	1	174	widely	widely	ADV
mkg-56898	1	175	used	use	VERB
mkg-56898	1	176	in	in	ADP
mkg-56898	1	177	temporomandibular	temporomandibular	ADJ
mkg-56898	1	178	joint	joint	ADJ
mkg-56898	1	179	osteoarthritis	osteoarthritis	NOUN
mkg-56898	1	180	management	management	NOUN
mkg-56898	1	181	.	.	PUNCT
mkg-56898	2	1	however	however	ADV
mkg-56898	2	2	,	,	PUNCT
mkg-56898	2	3	the	the	DET
mkg-56898	2	4	side	side	NOUN
mkg-56898	2	5	effects	effect	NOUN
mkg-56898	2	6	of	of	ADP
mkg-56898	2	7	nsaids	nsaid	NOUN
mkg-56898	2	8	on	on	ADP
mkg-56898	2	9	multiple	multiple	ADJ
mkg-56898	2	10	organs	organ	NOUN
mkg-56898	2	11	need	need	VERB
mkg-56898	2	12	to	to	PART
mkg-56898	2	13	be	be	AUX
mkg-56898	2	14	anticipated	anticipate	VERB
mkg-56898	2	15	.	.	PUNCT
mkg-56898	3	1	curcumin	curcumin	NOUN
mkg-56898	3	2	is	be	AUX
mkg-56898	3	3	known	know	VERB
mkg-56898	3	4	for	for	ADP
mkg-56898	3	5	its	its	PRON
mkg-56898	3	6	anti	anti	ADJ
mkg-56898	3	7	-	-	ADJ
mkg-56898	3	8	inflammatory	inflammatory	ADJ
mkg-56898	3	9	and	and	CCONJ
mkg-56898	3	10	analgesic	analgesic	ADJ
mkg-56898	3	11	potential	potential	NOUN
mkg-56898	3	12	,	,	PUNCT
mkg-56898	3	13	comparable	comparable	ADJ
mkg-56898	3	14	to	to	ADP
mkg-56898	3	15	that	that	PRON
mkg-56898	3	16	of	of	ADP
mkg-56898	3	17	nsaids	nsaid	NOUN
mkg-56898	3	18	.	.	PUNCT
mkg-56898	4	1	in	in	ADP
mkg-56898	4	2	a	a	DET
mkg-56898	4	3	previous	previous	ADJ
mkg-56898	4	4	study	study	NOUN
mkg-56898	4	5	,	,	PUNCT
mkg-56898	4	6	structurally	structurally	ADV
mkg-56898	4	7	modified	modify	VERB
mkg-56898	4	8	curcumin	curcumin	NOUN
mkg-56898	4	9	increased	increase	VERB
mkg-56898	4	10	the	the	DET
mkg-56898	4	11	pharmacological	pharmacological	ADJ
mkg-56898	4	12	effect	effect	NOUN
mkg-56898	4	13	and	and	CCONJ
mkg-56898	4	14	simultaneously	simultaneously	ADV
mkg-56898	4	15	reduced	reduce	VERB
mkg-56898	4	16	the	the	DET
mkg-56898	4	17	toxicity	toxicity	NOUN
mkg-56898	4	18	and	and	CCONJ
mkg-56898	4	19	side	side	NOUN
mkg-56898	4	20	effects	effect	NOUN
mkg-56898	4	21	of	of	ADP
mkg-56898	4	22	curcumin	curcumin	NOUN
mkg-56898	4	23	.	.	PUNCT
mkg-56898	5	1	pentagamavunon-0	pentagamavunon-0	NOUN
mkg-56898	5	2	(	(	PUNCT
mkg-56898	5	3	pgv-0	pgv-0	NOUN
mkg-56898	5	4	)	)	PUNCT
mkg-56898	5	5	is	be	AUX
mkg-56898	5	6	one	one	NUM
mkg-56898	5	7	of	of	ADP
mkg-56898	5	8	the	the	DET
mkg-56898	5	9	active	active	ADJ
mkg-56898	5	10	components	component	NOUN
mkg-56898	5	11	synthesized	synthesize	VERB
mkg-56898	5	12	by	by	ADP
mkg-56898	5	13	the	the	DET
mkg-56898	5	14	structure	structure	NOUN
mkg-56898	5	15	modification	modification	NOUN
mkg-56898	5	16	of	of	ADP
mkg-56898	5	17	curcumin	curcumin	NOUN
mkg-56898	5	18	.	.	PUNCT
mkg-56898	6	1	purpose	purpose	NOUN
mkg-56898	6	2	:	:	PUNCT
mkg-56898	6	3	in	in	ADP
mkg-56898	6	4	this	this	DET
mkg-56898	6	5	study	study	NOUN
mkg-56898	6	6	,	,	PUNCT
mkg-56898	6	7	we	we	PRON
mkg-56898	6	8	identify	identify	VERB
mkg-56898	6	9	the	the	DET
mkg-56898	6	10	potential	potential	ADJ
mkg-56898	6	11	target	target	NOUN
mkg-56898	6	12	of	of	ADP
mkg-56898	6	13	pgv-0	pgv-0	PUNCT
mkg-56898	6	14	on	on	ADP
mkg-56898	6	15	the	the	DET
mkg-56898	6	16	pathogenesis	pathogenesis	NOUN
mkg-56898	6	17	of	of	ADP
mkg-56898	6	18	temporomandibular	temporomandibular	ADJ
mkg-56898	6	19	arthritis	arthritis	NOUN
mkg-56898	6	20	characterized	characterize	VERB
mkg-56898	6	21	by	by	ADP
mkg-56898	6	22	inflammation	inflammation	NOUN
mkg-56898	6	23	.	.	PUNCT
mkg-56898	7	1	methods	method	NOUN
mkg-56898	7	2	:	:	PUNCT
mkg-56898	7	3	we	we	PRON
mkg-56898	7	4	used	use	VERB
mkg-56898	7	5	a	a	DET
mkg-56898	7	6	bioinformatics	bioinformatics	NOUN
mkg-56898	7	7	approach	approach	NOUN
mkg-56898	7	8	to	to	PART
mkg-56898	7	9	compare	compare	VERB
mkg-56898	7	10	the	the	DET
mkg-56898	7	11	pgv-0	pgv-0	PUNCT
mkg-56898	7	12	target	target	NOUN
mkg-56898	7	13	with	with	ADP
mkg-56898	7	14	curcumin	curcumin	NOUN
mkg-56898	7	15	and	and	CCONJ
mkg-56898	7	16	diclofenac	diclofenac	NOUN
mkg-56898	7	17	sodium	sodium	NOUN
mkg-56898	7	18	as	as	ADP
mkg-56898	7	19	controls	control	NOUN
mkg-56898	7	20	.	.	PUNCT
mkg-56898	8	1	we	we	PRON
mkg-56898	8	2	identified	identify	VERB
mkg-56898	8	3	overlapping	overlap	VERB
mkg-56898	8	4	gene	gene	NOUN
mkg-56898	8	5	targets	target	NOUN
mkg-56898	8	6	of	of	ADP
mkg-56898	8	7	bioactive	bioactive	ADJ
mkg-56898	8	8	compounds	compound	NOUN
mkg-56898	8	9	(	(	PUNCT
mkg-56898	8	10	pgv-0	pgv-0	NOUN
mkg-56898	8	11	,	,	PUNCT
mkg-56898	8	12	curcumin	curcumin	NOUN
mkg-56898	8	13	,	,	PUNCT
mkg-56898	8	14	or	or	CCONJ
mkg-56898	8	15	diclofenac	diclofenac	NOUN
mkg-56898	8	16	sodium	sodium	NOUN
mkg-56898	8	17	)	)	PUNCT
mkg-56898	8	18	retrieved	retrieve	VERB
mkg-56898	8	19	from	from	ADP
mkg-56898	8	20	the	the	DET
mkg-56898	8	21	swisstargetprediction	swisstargetprediction	NOUN
mkg-56898	8	22	and	and	CCONJ
mkg-56898	8	23	genecards	genecard	NOUN
mkg-56898	8	24	platforms	platform	NOUN
mkg-56898	8	25	,	,	PUNCT
mkg-56898	8	26	specifically	specifically	ADV
mkg-56898	8	27	for	for	ADP
mkg-56898	8	28	temporomandibular	temporomandibular	ADJ
mkg-56898	8	29	arthritis	arthritis	NOUN
mkg-56898	8	30	.	.	PUNCT
mkg-56898	9	1	an	an	DET
mkg-56898	9	2	interaction	interaction	NOUN
mkg-56898	9	3	model	model	NOUN
mkg-56898	9	4	among	among	ADP
mkg-56898	9	5	targets	target	NOUN
mkg-56898	9	6	was	be	AUX
mkg-56898	9	7	developed	develop	VERB
mkg-56898	9	8	using	use	VERB
mkg-56898	9	9	the	the	DET
mkg-56898	9	10	string	string	NOUN
mkg-56898	9	11	database	database	NOUN
mkg-56898	9	12	and	and	CCONJ
mkg-56898	9	13	gene	gene	NOUN
mkg-56898	9	14	ontology	ontology	NOUN
mkg-56898	9	15	panther	panther	NOUN
mkg-56898	9	16	to	to	PART
mkg-56898	9	17	expound	expound	VERB
mkg-56898	9	18	on	on	ADP
mkg-56898	9	19	the	the	DET
mkg-56898	9	20	bioactive	bioactive	PROPN
mkg-56898	9	21	compound	compound	PROPN
mkg-56898	9	22	’s	’s	PART
mkg-56898	9	23	function	function	NOUN
mkg-56898	9	24	on	on	ADP
mkg-56898	9	25	the	the	DET
mkg-56898	9	26	key	key	ADJ
mkg-56898	9	27	signaling	signal	VERB
mkg-56898	9	28	pathway	pathway	NOUN
mkg-56898	9	29	.	.	PUNCT
mkg-56898	10	1	finally	finally	ADV
mkg-56898	10	2	,	,	PUNCT
mkg-56898	10	3	we	we	PRON
mkg-56898	10	4	formulated	formulate	VERB
mkg-56898	10	5	a	a	DET
mkg-56898	10	6	molecular	molecular	ADJ
mkg-56898	10	7	docking	docking	NOUN
mkg-56898	10	8	prediction	prediction	NOUN
mkg-56898	10	9	between	between	ADP
mkg-56898	10	10	the	the	DET
mkg-56898	10	11	bioactive	bioactive	NOUN
mkg-56898	10	12	compound	compound	NOUN
mkg-56898	10	13	and	and	CCONJ
mkg-56898	10	14	the	the	DET
mkg-56898	10	15	target	target	NOUN
mkg-56898	10	16	protein	protein	NOUN
mkg-56898	10	17	marker	marker	NOUN
mkg-56898	10	18	derived	derive	VERB
mkg-56898	10	19	from	from	ADP
mkg-56898	10	20	the	the	DET
mkg-56898	10	21	previous	previous	ADJ
mkg-56898	10	22	analysis	analysis	NOUN
mkg-56898	10	23	using	use	VERB
mkg-56898	10	24	molecular	molecular	ADJ
mkg-56898	10	25	operating	operate	VERB
mkg-56898	10	26	environment	environment	NOUN
mkg-56898	10	27	tools	tool	NOUN
mkg-56898	10	28	.	.	PUNCT
mkg-56898	11	1	results	result	NOUN
mkg-56898	11	2	:	:	PUNCT
mkg-56898	11	3	this	this	DET
mkg-56898	11	4	study	study	NOUN
mkg-56898	11	5	found	find	VERB
mkg-56898	11	6	that	that	SCONJ
mkg-56898	11	7	curcumin	curcumin	NOUN
mkg-56898	11	8	and	and	CCONJ
mkg-56898	11	9	pgv-0	pgv-0	PUNCT
mkg-56898	11	10	targeted	target	VERB
mkg-56898	11	11	different	different	ADJ
mkg-56898	11	12	molecular	molecular	ADJ
mkg-56898	11	13	pathways	pathway	NOUN
mkg-56898	11	14	in	in	ADP
mkg-56898	11	15	temporomandibular	temporomandibular	ADJ
mkg-56898	11	16	arthritis	arthritis	NOUN
mkg-56898	11	17	compared	compare	VERB
mkg-56898	11	18	to	to	ADP
mkg-56898	11	19	diclofenac	diclofenac	VERB
mkg-56898	11	20	sodium	sodium	NOUN
mkg-56898	11	21	.	.	PUNCT
mkg-56898	12	1	curcumin	curcumin	NOUN
mkg-56898	12	2	and	and	CCONJ
mkg-56898	12	3	pgv-0	pgv-0	PUNCT
mkg-56898	12	4	shared	share	VERB
mkg-56898	12	5	a	a	DET
mkg-56898	12	6	similar	similar	ADJ
mkg-56898	12	7	pathway	pathway	NOUN
mkg-56898	12	8	to	to	PART
mkg-56898	12	9	curcumin	curcumin	VERB
mkg-56898	12	10	by	by	ADP
mkg-56898	12	11	modulating	modulate	VERB
mkg-56898	12	12	metalloproteinases	metalloproteinase	NOUN
mkg-56898	12	13	(	(	PUNCT
mkg-56898	12	14	mmps	mmp	NOUN
mkg-56898	12	15	)	)	PUNCT
mkg-56898	12	16	,	,	PUNCT
mkg-56898	12	17	especially	especially	ADV
mkg-56898	12	18	mmp-9	mmp-9	NOUN
mkg-56898	12	19	and	and	CCONJ
mkg-56898	12	20	mmp-13	mmp-13	NOUN
mkg-56898	12	21	.	.	PROPN
mkg-56898	13	1	moreover	moreover	ADV
mkg-56898	13	2	,	,	PUNCT
mkg-56898	13	3	diclofenac	diclofenac	ADJ
mkg-56898	13	4	sodium	sodium	NOUN
mkg-56898	13	5	influenced	influence	VERB
mkg-56898	13	6	cyclooxygenase	cyclooxygenase	NOUN
mkg-56898	13	7	metabolism	metabolism	NOUN
mkg-56898	13	8	.	.	PUNCT
mkg-56898	14	1	conclusion	conclusion	NOUN
mkg-56898	14	2	:	:	PUNCT
mkg-56898	14	3	in	in	ADP
mkg-56898	14	4	this	this	DET
mkg-56898	14	5	study	study	NOUN
mkg-56898	14	6	,	,	PUNCT
mkg-56898	14	7	pgv-0	pgv-0	PUNCT
mkg-56898	14	8	targeted	target	VERB
mkg-56898	14	9	metalloproteinase	metalloproteinase	NOUN
mkg-56898	14	10	in	in	ADP
mkg-56898	14	11	temporomandibular	temporomandibular	ADJ
mkg-56898	14	12	arthritis	arthritis	NOUN
mkg-56898	14	13	pathogenesis	pathogenesis	NOUN
mkg-56898	14	14	.	.	PUNCT
mkg-56898	15	1	this	this	DET
mkg-56898	15	2	finding	finding	NOUN
mkg-56898	15	3	underlines	underline	VERB
mkg-56898	15	4	the	the	DET
mkg-56898	15	5	pgv-0	pgv-0	PUNCT
mkg-56898	15	6	advantage	advantage	NOUN
mkg-56898	15	7	in	in	ADP
mkg-56898	15	8	preventing	prevent	VERB
mkg-56898	15	9	metalloproteinase	metalloproteinase	NOUN
mkg-56898	15	10	-	-	PUNCT
mkg-56898	15	11	related	relate	VERB
mkg-56898	15	12	tissue	tissue	NOUN
mkg-56898	15	13	damage	damage	NOUN
mkg-56898	15	14	in	in	ADP
mkg-56898	15	15	temporomandibular	temporomandibular	ADJ
mkg-56898	15	16	arthritis	arthritis	NOUN
mkg-56898	15	17	.	.	PUNCT
mkg-56898	16	1	keywords	keyword	NOUN
mkg-56898	16	2	:	:	PUNCT
mkg-56898	16	3	anti	anti	ADJ
mkg-56898	16	4	-	-	ADJ
mkg-56898	16	5	inflammatory	inflammatory	ADJ
mkg-56898	16	6	agent	agent	NOUN
mkg-56898	16	7	;	;	PUNCT
mkg-56898	16	8	cyclooxygenase	cyclooxygenase	NOUN
mkg-56898	16	9	;	;	PUNCT
mkg-56898	16	10	curcumin	curcumin	NOUN
mkg-56898	16	11	;	;	PUNCT
mkg-56898	16	12	diclofenac	diclofenac	NOUN
mkg-56898	16	13	sodium	sodium	NOUN
mkg-56898	16	14	;	;	PUNCT
mkg-56898	16	15	chronic	chronic	ADJ
mkg-56898	16	16	inflammation	inflammation	NOUN
mkg-56898	16	17	;	;	PUNCT
mkg-56898	16	18	metalloproteinase	metalloproteinase	PROPN
mkg-56898	16	19	article	article	NOUN
mkg-56898	16	20	history	history	NOUN
mkg-56898	16	21	:	:	PUNCT
mkg-56898	16	22	received	receive	VERB
mkg-56898	16	23	26	26	NUM
mkg-56898	16	24	april	april	PROPN
mkg-56898	16	25	2024	2024	NUM
mkg-56898	16	26	;	;	PUNCT
mkg-56898	16	27	revised	revise	VERB
mkg-56898	16	28	20	20	NUM
mkg-56898	16	29	august	august	PROPN
mkg-56898	16	30	2024	2024	NUM
mkg-56898	16	31	;	;	PUNCT
mkg-56898	16	32	accepted	accept	VERB
mkg-56898	16	33	17	17	NUM
mkg-56898	16	34	october	october	PROPN
mkg-56898	16	35	2024	2024	NUM
mkg-56898	16	36	;	;	PUNCT
mkg-56898	16	37	online	online	ADV
mkg-56898	16	38	10	10	NUM
mkg-56898	16	39	september	september	PROPN
mkg-56898	16	40	2025	2025	NUM
mkg-56898	16	41	correspondence	correspondence	NOUN
mkg-56898	16	42	:	:	PUNCT
mkg-56898	16	43	nunuk	nunuk	PROPN
mkg-56898	16	44	purwanti	purwanti	PROPN
mkg-56898	16	45	,	,	PUNCT
mkg-56898	16	46	department	department	NOUN
mkg-56898	16	47	of	of	ADP
mkg-56898	16	48	dental	dental	ADJ
mkg-56898	16	49	biomedical	biomedical	ADJ
mkg-56898	16	50	sciences	science	NOUN
mkg-56898	16	51	,	,	PUNCT
mkg-56898	16	52	faculty	faculty	NOUN
mkg-56898	16	53	of	of	ADP
mkg-56898	16	54	dentistry	dentistry	NOUN
mkg-56898	16	55	,	,	PUNCT
mkg-56898	16	56	universitas	universita	NOUN
mkg-56898	16	57	gadjah	gadjah	PROPN
mkg-56898	16	58	mada	mada	PROPN
mkg-56898	16	59	,	,	PUNCT
mkg-56898	16	60	jalan	jalan	PROPN
mkg-56898	16	61	denta	denta	PROPN
mkg-56898	16	62	sekip	sekip	ADJ
mkg-56898	16	63	utara	utara	NOUN
mkg-56898	16	64	,	,	PUNCT
mkg-56898	16	65	sleman	sleman	NOUN
mkg-56898	16	66	,	,	PUNCT
mkg-56898	16	67	yogyakarta	yogyakarta	PROPN
mkg-56898	16	68	,	,	PUNCT
mkg-56898	16	69	indonesia	indonesia	PROPN
mkg-56898	16	70	.	.	PUNCT
mkg-56898	17	1	email	email	NOUN
mkg-56898	17	2	:	:	PUNCT
mkg-56898	17	3	n_purwanti@mail.ugm.ac.id	n_purwanti@mail.ugm.ac.id	ADJ
mkg-56898	17	4	introduction	introduction	NOUN
mkg-56898	17	5	pain	pain	NOUN
mkg-56898	17	6	in	in	ADP
mkg-56898	17	7	the	the	DET
mkg-56898	17	8	oral	oral	ADJ
mkg-56898	17	9	and	and	CCONJ
mkg-56898	17	10	maxillofacial	maxillofacial	ADJ
mkg-56898	17	11	area	area	NOUN
mkg-56898	17	12	is	be	AUX
mkg-56898	17	13	commonly	commonly	ADV
mkg-56898	17	14	derived	derive	VERB
mkg-56898	17	15	from	from	ADP
mkg-56898	17	16	the	the	DET
mkg-56898	17	17	tooth	tooth	NOUN
mkg-56898	17	18	or	or	CCONJ
mkg-56898	17	19	the	the	DET
mkg-56898	17	20	temporomandibular	temporomandibular	ADJ
mkg-56898	17	21	joint	joint	NOUN
mkg-56898	17	22	(	(	PUNCT
mkg-56898	17	23	tmj	tmj	PROPN
mkg-56898	17	24	)	)	PUNCT
mkg-56898	17	25	.	.	PUNCT
mkg-56898	18	1	patients	patient	NOUN
mkg-56898	18	2	with	with	ADP
mkg-56898	18	3	tmj	tmj	PROPN
mkg-56898	18	4	disorder	disorder	NOUN
mkg-56898	18	5	report	report	VERB
mkg-56898	18	6	light	light	ADJ
mkg-56898	18	7	pain	pain	NOUN
mkg-56898	18	8	to	to	ADP
mkg-56898	18	9	severe	severe	ADJ
mkg-56898	18	10	dysfunction	dysfunction	NOUN
mkg-56898	18	11	that	that	PRON
mkg-56898	18	12	plausibly	plausibly	ADV
mkg-56898	18	13	debilitates	debilitate	VERB
mkg-56898	18	14	wellness	wellness	NOUN
mkg-56898	18	15	.	.	PUNCT
mkg-56898	19	1	a	a	DET
mkg-56898	19	2	metaanalysis	metaanalysis	NOUN
mkg-56898	19	3	study	study	NOUN
mkg-56898	19	4	indicated	indicate	VERB
mkg-56898	19	5	the	the	DET
mkg-56898	19	6	worldwide	worldwide	ADJ
mkg-56898	19	7	prevalence	prevalence	NOUN
mkg-56898	19	8	of	of	ADP
mkg-56898	19	9	tmj	tmj	PROPN
mkg-56898	19	10	disorder	disorder	NOUN
mkg-56898	19	11	in	in	ADP
mkg-56898	19	12	adults	adult	NOUN
mkg-56898	19	13	/	/	SYM
mkg-56898	19	14	elderly	elderly	ADJ
mkg-56898	19	15	(	(	PUNCT
mkg-56898	19	16	aged	aged	ADJ
mkg-56898	19	17	20–75	20–75	NUM
mkg-56898	19	18	years	year	NOUN
mkg-56898	19	19	)	)	PUNCT
mkg-56898	19	20	and	and	CCONJ
mkg-56898	19	21	children/	children/	NUM
mkg-56898	19	22	adolescents	adolescent	NOUN
mkg-56898	19	23	(	(	PUNCT
mkg-56898	19	24	aged	aged	ADJ
mkg-56898	19	25	7–19	7–19	NOUN
mkg-56898	19	26	years	year	NOUN
mkg-56898	19	27	)	)	PUNCT
mkg-56898	19	28	as	as	ADP
mkg-56898	19	29	31.1	31.1	NUM
mkg-56898	19	30	%	%	NOUN
mkg-56898	19	31	and	and	CCONJ
mkg-56898	19	32	11.3	11.3	NUM
mkg-56898	19	33	%	%	NOUN
mkg-56898	19	34	,	,	PUNCT
mkg-56898	19	35	respectively.1	respectively.1	PROPN
mkg-56898	19	36	in	in	ADP
mkg-56898	19	37	indonesia	indonesia	PROPN
mkg-56898	19	38	,	,	PUNCT
mkg-56898	19	39	pain	pain	NOUN
mkg-56898	19	40	-	-	PUNCT
mkg-56898	19	41	related	relate	VERB
mkg-56898	19	42	tmj	tmj	NOUN
mkg-56898	19	43	disorder	disorder	NOUN
mkg-56898	19	44	is	be	AUX
mkg-56898	19	45	found	find	VERB
mkg-56898	19	46	in	in	ADP
mkg-56898	19	47	23.4	23.4	NUM
mkg-56898	19	48	%	%	NOUN
mkg-56898	19	49	(	(	PUNCT
mkg-56898	19	50	95	95	NUM
mkg-56898	19	51	%	%	NOUN
mkg-56898	19	52	ci	ci	NOUN
mkg-56898	19	53	=	=	SYM
mkg-56898	19	54	20–27	20–27	NUM
mkg-56898	19	55	)	)	PUNCT
mkg-56898	19	56	of	of	ADP
mkg-56898	19	57	children	child	NOUN
mkg-56898	19	58	and	and	CCONJ
mkg-56898	19	59	36.9	36.9	NUM
mkg-56898	19	60	%	%	NOUN
mkg-56898	19	61	of	of	ADP
mkg-56898	19	62	adolescents	adolescent	NOUN
mkg-56898	19	63	(	(	PUNCT
mkg-56898	19	64	95	95	NUM
mkg-56898	19	65	%	%	NOUN
mkg-56898	19	66	ci	ci	NOUN
mkg-56898	20	1	=	=	PUNCT
mkg-56898	20	2	33–41).2	33–41).2	NUM
mkg-56898	20	3	a	a	DET
mkg-56898	20	4	systematic	systematic	ADJ
mkg-56898	20	5	review	review	NOUN
mkg-56898	20	6	of	of	ADP
mkg-56898	20	7	86	86	NUM
mkg-56898	20	8	clinical	clinical	ADJ
mkg-56898	20	9	and	and	CCONJ
mkg-56898	20	10	in	in	ADP
mkg-56898	20	11	vivo	vivo	ADJ
mkg-56898	20	12	studies	study	NOUN
mkg-56898	20	13	reported	report	VERB
mkg-56898	20	14	a	a	DET
mkg-56898	20	15	common	common	ADJ
mkg-56898	20	16	finding	finding	NOUN
mkg-56898	20	17	among	among	ADP
mkg-56898	20	18	them	they	PRON
mkg-56898	20	19	on	on	ADP
mkg-56898	20	20	the	the	DET
mkg-56898	20	21	increase	increase	NOUN
mkg-56898	20	22	of	of	ADP
mkg-56898	20	23	inflammation	inflammation	NOUN
mkg-56898	20	24	cytokines	cytokine	NOUN
mkg-56898	20	25	and	and	CCONJ
mkg-56898	20	26	inflammatory	inflammatory	ADJ
mkg-56898	20	27	markers	marker	NOUN
mkg-56898	20	28	—	—	PUNCT
mkg-56898	20	29	including	include	VERB
mkg-56898	20	30	interleukin	interleukin	NOUN
mkg-56898	20	31	(	(	PUNCT
mkg-56898	20	32	il)1β	il)1β	NOUN
mkg-56898	20	33	,	,	PUNCT
mkg-56898	20	34	il-2	il-2	PROPN
mkg-56898	20	35	,	,	PUNCT
mkg-56898	20	36	il-6	il-6	PRON
mkg-56898	20	37	,	,	PUNCT
mkg-56898	20	38	il-8	il-8	NOUN
mkg-56898	20	39	,	,	PUNCT
mkg-56898	20	40	and	and	CCONJ
mkg-56898	20	41	il-10	il-10	PRON
mkg-56898	20	42	,	,	PUNCT
mkg-56898	20	43	tumor	tumor	NOUN
mkg-56898	20	44	necrosis	necrosis	NOUN
mkg-56898	20	45	factor	factor	NOUN
mkg-56898	20	46	alpha	alpha	NOUN
mkg-56898	20	47	(	(	PUNCT
mkg-56898	20	48	tnf	tnf	PROPN
mkg-56898	20	49	-	-	PUNCT
mkg-56898	20	50	α	α	NOUN
mkg-56898	20	51	)	)	PUNCT
mkg-56898	20	52	,	,	PUNCT
mkg-56898	20	53	and	and	CCONJ
mkg-56898	20	54	bradykinin	bradykinin	PROPN
mkg-56898	20	55	—	—	PUNCT
mkg-56898	20	56	in	in	ADP
mkg-56898	20	57	the	the	DET
mkg-56898	20	58	synovial	synovial	ADJ
mkg-56898	20	59	fluid	fluid	NOUN
mkg-56898	20	60	of	of	ADP
mkg-56898	20	61	individuals	individual	NOUN
mkg-56898	20	62	with	with	ADP
mkg-56898	20	63	tmj	tmj	PROPN
mkg-56898	20	64	disorder.3	disorder.3	PROPN
mkg-56898	20	65	copyright	copyright	NOUN
mkg-56898	20	66	©	©	PROPN
mkg-56898	20	67	2025	2025	NUM
mkg-56898	20	68	dental	dental	ADJ
mkg-56898	20	69	journal	journal	NOUN
mkg-56898	20	70	(	(	PUNCT
mkg-56898	20	71	majalah	majalah	PROPN
mkg-56898	20	72	kedokteran	kedokteran	PROPN
mkg-56898	20	73	gigi	gigi	PROPN
mkg-56898	20	74	)	)	PUNCT
mkg-56898	21	1	p	p	X
mkg-56898	21	2	-	-	PUNCT
mkg-56898	21	3	issn	issn	NOUN
mkg-56898	21	4	:	:	PUNCT
mkg-56898	21	5	1978	1978	NUM
mkg-56898	21	6	-	-	SYM
mkg-56898	21	7	3728	3728	NUM
mkg-56898	21	8	;	;	PUNCT
mkg-56898	21	9	e	e	X
mkg-56898	21	10	-	-	PUNCT
mkg-56898	21	11	issn	issn	ADJ
mkg-56898	21	12	:	:	PUNCT
mkg-56898	21	13	2442	2442	NUM
mkg-56898	21	14	-	-	SYM
mkg-56898	21	15	9740	9740	NUM
mkg-56898	21	16	.	.	PUNCT
mkg-56898	22	1	accredited	accredit	VERB
mkg-56898	22	2	no	no	INTJ
mkg-56898	22	3	.	.	PROPN
mkg-56898	23	1	158	158	NUM
mkg-56898	23	2	/	/	SYM
mkg-56898	23	3	e	e	NOUN
mkg-56898	23	4	/	/	SYM
mkg-56898	23	5	kpt/2021	kpt/2021	NOUN
mkg-56898	23	6	.	.	PUNCT
mkg-56898	24	1	open	open	ADJ
mkg-56898	24	2	access	access	NOUN
mkg-56898	24	3	under	under	ADP
mkg-56898	24	4	cc	cc	NOUN
mkg-56898	24	5	-	-	PUNCT
mkg-56898	24	6	by	by	ADP
mkg-56898	24	7	-	-	PUNCT
mkg-56898	24	8	sa	sa	NOUN
mkg-56898	24	9	license	license	NOUN
mkg-56898	24	10	.	.	PUNCT
mkg-56898	25	1	available	available	ADJ
mkg-56898	25	2	at	at	ADP
mkg-56898	25	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	25	4	doi	doi	NOUN
mkg-56898	25	5	:	:	PUNCT
mkg-56898	25	6	10.20473	10.20473	NUM
mkg-56898	25	7	/	/	SYM
mkg-56898	25	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	ADJ
mkg-56898	25	9	mailto:n_purwanti@mail.ugm.ac.id	mailto:n_purwanti@mail.ugm.ac.id	X
mkg-56898	25	10	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	25	11	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	26	1	368	368	NUM
mkg-56898	26	2	robin	robin	PROPN
mkg-56898	26	3	et	et	PROPN
mkg-56898	26	4	al	al	PROPN
mkg-56898	26	5	.	.	PROPN
mkg-56898	26	6	dent	dent	PROPN
mkg-56898	26	7	.	.	PUNCT
mkg-56898	27	1	j.	j.	PROPN
mkg-56898	27	2	(	(	PUNCT
mkg-56898	27	3	majalah	majalah	PROPN
mkg-56898	27	4	kedokteran	kedokteran	PROPN
mkg-56898	27	5	gigi	gigi	PROPN
mkg-56898	27	6	)	)	PUNCT
mkg-56898	27	7	2025	2025	NUM
mkg-56898	27	8	december	december	NOUN
mkg-56898	27	9	;	;	PUNCT
mkg-56898	27	10	58(4	58(4	NUM
mkg-56898	27	11	):	):	PUNCT
mkg-56898	27	12	367–375	367–375	NUM
mkg-56898	27	13	the	the	DET
mkg-56898	27	14	most	most	ADV
mkg-56898	27	15	common	common	ADJ
mkg-56898	27	16	tmj	tmj	NOUN
mkg-56898	27	17	disorder	disorder	NOUN
mkg-56898	27	18	is	be	AUX
mkg-56898	27	19	osteoarthritis	osteoarthritis	NOUN
mkg-56898	27	20	(	(	PUNCT
mkg-56898	27	21	oa	oa	PROPN
mkg-56898	27	22	)	)	PUNCT
mkg-56898	27	23	,	,	PUNCT
mkg-56898	27	24	a	a	DET
mkg-56898	27	25	form	form	NOUN
mkg-56898	27	26	of	of	ADP
mkg-56898	27	27	arthritis	arthritis	NOUN
mkg-56898	27	28	characterized	characterize	VERB
mkg-56898	27	29	by	by	ADP
mkg-56898	27	30	a	a	DET
mkg-56898	27	31	chronic	chronic	ADJ
mkg-56898	27	32	degeneration	degeneration	NOUN
mkg-56898	27	33	of	of	ADP
mkg-56898	27	34	joint	joint	ADJ
mkg-56898	27	35	tissue	tissue	NOUN
mkg-56898	27	36	.	.	PUNCT
mkg-56898	28	1	clinically	clinically	ADV
mkg-56898	28	2	,	,	PUNCT
mkg-56898	28	3	patients	patient	NOUN
mkg-56898	28	4	with	with	ADP
mkg-56898	28	5	tmj	tmj	PROPN
mkg-56898	28	6	-	-	PUNCT
mkg-56898	28	7	oa	oa	PROPN
mkg-56898	28	8	report	report	NOUN
mkg-56898	28	9	pain	pain	NOUN
mkg-56898	28	10	,	,	PUNCT
mkg-56898	28	11	limited	limited	ADJ
mkg-56898	28	12	movement	movement	NOUN
mkg-56898	28	13	,	,	PUNCT
mkg-56898	28	14	and	and	CCONJ
mkg-56898	28	15	destruction	destruction	NOUN
mkg-56898	28	16	of	of	ADP
mkg-56898	28	17	cartilage	cartilage	NOUN
mkg-56898	28	18	tissue	tissue	NOUN
mkg-56898	28	19	that	that	PRON
mkg-56898	28	20	is	be	AUX
mkg-56898	28	21	likely	likely	ADV
mkg-56898	28	22	accompanied	accompany	VERB
mkg-56898	28	23	by	by	ADP
mkg-56898	28	24	bone	bone	NOUN
mkg-56898	28	25	absorption.3–5	absorption.3–5	NOUN
mkg-56898	28	26	these	these	DET
mkg-56898	28	27	pathologic	pathologic	ADJ
mkg-56898	28	28	events	event	NOUN
mkg-56898	28	29	in	in	ADP
mkg-56898	28	30	tmj	tmj	PROPN
mkg-56898	28	31	-	-	PUNCT
mkg-56898	28	32	oa	oa	NOUN
mkg-56898	28	33	are	be	AUX
mkg-56898	28	34	known	know	VERB
mkg-56898	28	35	to	to	PART
mkg-56898	28	36	be	be	AUX
mkg-56898	28	37	associated	associate	VERB
mkg-56898	28	38	with	with	ADP
mkg-56898	28	39	chronic	chronic	ADJ
mkg-56898	28	40	inflammation	inflammation	NOUN
mkg-56898	28	41	of	of	ADP
mkg-56898	28	42	joint	joint	ADJ
mkg-56898	28	43	tissue.5,6	tissue.5,6	PROPN
mkg-56898	28	44	diclofenac	diclofenac	ADJ
mkg-56898	28	45	sodium	sodium	NOUN
mkg-56898	28	46	is	be	AUX
mkg-56898	28	47	a	a	DET
mkg-56898	28	48	non	non	ADJ
mkg-56898	28	49	-	-	ADJ
mkg-56898	28	50	steroidal	steroidal	ADJ
mkg-56898	28	51	anti	anti	ADJ
mkg-56898	28	52	-	-	ADJ
mkg-56898	28	53	inflammatory	inflammatory	ADJ
mkg-56898	28	54	drug	drug	NOUN
mkg-56898	28	55	(	(	PUNCT
mkg-56898	28	56	nsaid	nsaid	PROPN
mkg-56898	28	57	)	)	PUNCT
mkg-56898	28	58	that	that	PRON
mkg-56898	28	59	is	be	AUX
mkg-56898	28	60	widely	widely	ADV
mkg-56898	28	61	prescribed	prescribe	VERB
mkg-56898	28	62	to	to	PART
mkg-56898	28	63	reduce	reduce	VERB
mkg-56898	28	64	pain	pain	NOUN
mkg-56898	28	65	and	and	CCONJ
mkg-56898	28	66	inflammation	inflammation	NOUN
mkg-56898	28	67	in	in	ADP
mkg-56898	28	68	the	the	DET
mkg-56898	28	69	temporomandibular	temporomandibular	ADJ
mkg-56898	28	70	disorder	disorder	NOUN
mkg-56898	28	71	.	.	PUNCT
mkg-56898	29	1	long	long	ADJ
mkg-56898	29	2	-	-	PUNCT
mkg-56898	29	3	term	term	NOUN
mkg-56898	29	4	use	use	NOUN
mkg-56898	29	5	of	of	ADP
mkg-56898	29	6	nsaids	nsaid	NOUN
mkg-56898	29	7	causes	cause	VERB
mkg-56898	29	8	side	side	ADJ
mkg-56898	29	9	effects	effect	NOUN
mkg-56898	29	10	on	on	ADP
mkg-56898	29	11	the	the	DET
mkg-56898	29	12	gastrointestinal	gastrointestinal	ADJ
mkg-56898	29	13	,	,	PUNCT
mkg-56898	29	14	cardiovascular	cardiovascular	ADJ
mkg-56898	29	15	,	,	PUNCT
mkg-56898	29	16	hepatic	hepatic	ADJ
mkg-56898	29	17	,	,	PUNCT
mkg-56898	29	18	renal	renal	ADJ
mkg-56898	29	19	,	,	PUNCT
mkg-56898	29	20	cerebral	cerebral	ADJ
mkg-56898	29	21	,	,	PUNCT
mkg-56898	29	22	and	and	CCONJ
mkg-56898	29	23	pulmonary	pulmonary	ADJ
mkg-56898	29	24	organs.7–11	organs.7–11	ADV
mkg-56898	29	25	as	as	ADP
mkg-56898	29	26	an	an	DET
mkg-56898	29	27	alternative	alternative	ADJ
mkg-56898	29	28	natural	natural	ADJ
mkg-56898	29	29	ingredient	ingredient	NOUN
mkg-56898	29	30	to	to	ADP
mkg-56898	29	31	nsaids	nsaid	NOUN
mkg-56898	29	32	,	,	PUNCT
mkg-56898	29	33	curcumin	curcumin	NOUN
mkg-56898	29	34	has	have	AUX
mkg-56898	29	35	been	be	AUX
mkg-56898	29	36	proven	prove	VERB
mkg-56898	29	37	to	to	PART
mkg-56898	29	38	have	have	VERB
mkg-56898	29	39	anti	anti	ADJ
mkg-56898	29	40	-	-	ADJ
mkg-56898	29	41	inflammatory	inflammatory	ADJ
mkg-56898	29	42	potential	potential	NOUN
mkg-56898	29	43	in	in	ADP
mkg-56898	29	44	tmjoa.10,12	tmjoa.10,12	NOUN
mkg-56898	29	45	however	however	ADV
mkg-56898	29	46	,	,	PUNCT
mkg-56898	29	47	the	the	DET
mkg-56898	29	48	compound	compound	NOUN
mkg-56898	29	49	is	be	AUX
mkg-56898	29	50	unstable	unstable	ADJ
mkg-56898	29	51	and	and	CCONJ
mkg-56898	29	52	strongly	strongly	ADV
mkg-56898	29	53	influenced	influence	VERB
mkg-56898	29	54	by	by	ADP
mkg-56898	29	55	environmental	environmental	ADJ
mkg-56898	29	56	ph	ph	NOUN
mkg-56898	29	57	and	and	CCONJ
mkg-56898	29	58	light	light	NOUN
mkg-56898	29	59	.	.	PUNCT
mkg-56898	30	1	furthermore	furthermore	ADV
mkg-56898	30	2	,	,	PUNCT
mkg-56898	30	3	curcumin	curcumin	NOUN
mkg-56898	30	4	has	have	VERB
mkg-56898	30	5	low	low	ADJ
mkg-56898	30	6	oral	oral	ADJ
mkg-56898	30	7	bioavailability	bioavailability	NOUN
mkg-56898	30	8	because	because	SCONJ
mkg-56898	30	9	of	of	ADP
mkg-56898	30	10	its	its	PRON
mkg-56898	30	11	low	low	ADJ
mkg-56898	30	12	solubility	solubility	NOUN
mkg-56898	30	13	in	in	ADP
mkg-56898	30	14	aqueous	aqueous	ADJ
mkg-56898	30	15	solutions	solution	NOUN
mkg-56898	30	16	,	,	PUNCT
mkg-56898	30	17	instability	instability	NOUN
mkg-56898	30	18	in	in	ADP
mkg-56898	30	19	metabolic	metabolic	NOUN
mkg-56898	30	20	processes	process	NOUN
mkg-56898	30	21	,	,	PUNCT
mkg-56898	30	22	and	and	CCONJ
mkg-56898	30	23	difficulty	difficulty	NOUN
mkg-56898	30	24	in	in	ADP
mkg-56898	30	25	absorbing.13	absorbing.13	PROPN
mkg-56898	30	26	pentagamavunon-0	pentagamavunon-0	ADV
mkg-56898	30	27	(	(	PUNCT
mkg-56898	30	28	pgv-0	pgv-0	NOUN
mkg-56898	30	29	)	)	PUNCT
mkg-56898	30	30	or	or	CCONJ
mkg-56898	30	31	2,5	2,5	NUM
mkg-56898	30	32	-	-	PUNCT
mkg-56898	30	33	bis(4’-hydroxy3	bis(4’-hydroxy3	NOUN
mkg-56898	30	34	-	-	PUNCT
mkg-56898	30	35	methoxybenzylidine	methoxybenzylidine	NOUN
mkg-56898	30	36	)	)	PUNCT
mkg-56898	31	1	cyclopentanone	cyclopentanone	NOUN
mkg-56898	31	2	is	be	AUX
mkg-56898	31	3	an	an	DET
mkg-56898	31	4	analog	analog	NOUN
mkg-56898	31	5	of	of	ADP
mkg-56898	31	6	curcumin	curcumin	NOUN
mkg-56898	31	7	(	(	PUNCT
mkg-56898	31	8	1,7	1,7	NUM
mkg-56898	31	9	-	-	PUNCT
mkg-56898	31	10	bis-[4’-hydroxy-3	bis-[4’-hydroxy-3	NOUN
mkg-56898	31	11	-	-	PUNCT
mkg-56898	31	12	methoxyphenyl]-hepta1,6	methoxyphenyl]-hepta1,6	NOUN
mkg-56898	31	13	-	-	PUNCT
mkg-56898	31	14	diene-3,5	diene-3,5	NOUN
mkg-56898	31	15	-	-	PUNCT
mkg-56898	31	16	dione	dione	NOUN
mkg-56898	31	17	)	)	PUNCT
mkg-56898	31	18	.	.	PUNCT
mkg-56898	32	1	the	the	DET
mkg-56898	32	2	pgv-0	pgv-0	PUNCT
mkg-56898	32	3	synthesis	synthesis	NOUN
mkg-56898	32	4	increases	increase	NOUN
mkg-56898	32	5	curcumin	curcumin	NOUN
mkg-56898	32	6	’s	’s	PART
mkg-56898	32	7	water	water	NOUN
mkg-56898	32	8	solubility	solubility	NOUN
mkg-56898	32	9	and	and	CCONJ
mkg-56898	32	10	stability	stability	NOUN
mkg-56898	32	11	at	at	ADP
mkg-56898	32	12	ph	ph	PROPN
mkg-56898	32	13	>	>	X
mkg-56898	32	14	6.5	6.5	NUM
mkg-56898	32	15	.	.	PUNCT
mkg-56898	33	1	this	this	DET
mkg-56898	33	2	molecule	molecule	NOUN
mkg-56898	33	3	has	have	VERB
mkg-56898	33	4	vast	vast	ADJ
mkg-56898	33	5	biological	biological	ADJ
mkg-56898	33	6	properties	property	NOUN
mkg-56898	33	7	,	,	PUNCT
mkg-56898	33	8	such	such	ADJ
mkg-56898	33	9	as	as	ADP
mkg-56898	33	10	antiinflammatory	antiinflammatory	NOUN
mkg-56898	33	11	,	,	PUNCT
mkg-56898	33	12	antioxidant	antioxidant	NOUN
mkg-56898	33	13	,	,	PUNCT
mkg-56898	33	14	and	and	CCONJ
mkg-56898	33	15	antimicrobial	antimicrobial	ADJ
mkg-56898	33	16	properties	property	NOUN
mkg-56898	33	17	.	.	PUNCT
mkg-56898	34	1	the	the	DET
mkg-56898	34	2	anti	anti	ADJ
mkg-56898	34	3	-	-	ADJ
mkg-56898	34	4	inflammatory	inflammatory	ADJ
mkg-56898	34	5	property	property	NOUN
mkg-56898	34	6	of	of	ADP
mkg-56898	34	7	pgv-0	pgv-0	PUNCT
mkg-56898	34	8	is	be	AUX
mkg-56898	34	9	reportedly	reportedly	ADV
mkg-56898	34	10	similar	similar	ADJ
mkg-56898	34	11	to	to	ADP
mkg-56898	34	12	or	or	CCONJ
mkg-56898	34	13	better	well	ADJ
mkg-56898	34	14	than	than	ADP
mkg-56898	34	15	that	that	PRON
mkg-56898	34	16	of	of	ADP
mkg-56898	34	17	curcumin.14–16	curcumin.14–16	NOUN
mkg-56898	34	18	therefore	therefore	ADV
mkg-56898	34	19	,	,	PUNCT
mkg-56898	34	20	we	we	PRON
mkg-56898	34	21	postulated	postulate	VERB
mkg-56898	34	22	that	that	SCONJ
mkg-56898	34	23	pgv-0	pgv-0	PUNCT
mkg-56898	34	24	would	would	AUX
mkg-56898	34	25	work	work	VERB
mkg-56898	34	26	as	as	ADP
mkg-56898	34	27	an	an	DET
mkg-56898	34	28	anti	anti	ADJ
mkg-56898	34	29	-	-	ADJ
mkg-56898	34	30	inflammatory	inflammatory	ADJ
mkg-56898	34	31	agent	agent	NOUN
mkg-56898	34	32	in	in	ADP
mkg-56898	34	33	temporomandibular	temporomandibular	ADJ
mkg-56898	34	34	arthritis	arthritis	NOUN
mkg-56898	34	35	.	.	PUNCT
mkg-56898	35	1	however	however	ADV
mkg-56898	35	2	,	,	PUNCT
mkg-56898	35	3	no	no	DET
mkg-56898	35	4	previous	previous	ADJ
mkg-56898	35	5	research	research	NOUN
mkg-56898	35	6	has	have	AUX
mkg-56898	35	7	reported	report	VERB
mkg-56898	35	8	the	the	DET
mkg-56898	35	9	potential	potential	ADJ
mkg-56898	35	10	target	target	NOUN
mkg-56898	35	11	of	of	ADP
mkg-56898	35	12	the	the	DET
mkg-56898	35	13	pgv-0	pgv-0	PUNCT
mkg-56898	35	14	in	in	ADP
mkg-56898	35	15	temporomandibular	temporomandibular	ADJ
mkg-56898	35	16	arthritis	arthritis	NOUN
mkg-56898	35	17	.	.	PUNCT
mkg-56898	36	1	this	this	DET
mkg-56898	36	2	study	study	NOUN
mkg-56898	36	3	thus	thus	ADV
mkg-56898	36	4	aimed	aim	VERB
mkg-56898	36	5	to	to	PART
mkg-56898	36	6	identify	identify	VERB
mkg-56898	36	7	the	the	DET
mkg-56898	36	8	potential	potential	ADJ
mkg-56898	36	9	target	target	NOUN
mkg-56898	36	10	of	of	ADP
mkg-56898	36	11	pgv-0	pgv-0	PUNCT
mkg-56898	36	12	on	on	ADP
mkg-56898	36	13	the	the	DET
mkg-56898	36	14	pathogenesis	pathogenesis	NOUN
mkg-56898	36	15	of	of	ADP
mkg-56898	36	16	temporomandibular	temporomandibular	ADJ
mkg-56898	36	17	arthritis	arthritis	NOUN
mkg-56898	36	18	characterized	characterize	VERB
mkg-56898	36	19	by	by	ADP
mkg-56898	36	20	inflammation	inflammation	NOUN
mkg-56898	36	21	.	.	PUNCT
mkg-56898	37	1	we	we	PRON
mkg-56898	37	2	elucidate	elucidate	VERB
mkg-56898	37	3	the	the	DET
mkg-56898	37	4	potential	potential	ADJ
mkg-56898	37	5	target	target	NOUN
mkg-56898	37	6	of	of	ADP
mkg-56898	37	7	pgv-0	pgv-0	PUNCT
mkg-56898	37	8	in	in	ADP
mkg-56898	37	9	temporomandibular	temporomandibular	ADJ
mkg-56898	37	10	arthritis	arthritis	NOUN
mkg-56898	37	11	by	by	ADP
mkg-56898	37	12	using	use	VERB
mkg-56898	37	13	a	a	DET
mkg-56898	37	14	bioinformatics	bioinformatics	NOUN
mkg-56898	37	15	approach	approach	NOUN
mkg-56898	37	16	to	to	PART
mkg-56898	37	17	analyze	analyze	VERB
mkg-56898	37	18	,	,	PUNCT
mkg-56898	37	19	identify	identify	VERB
mkg-56898	37	20	,	,	PUNCT
mkg-56898	37	21	and	and	CCONJ
mkg-56898	37	22	interpret	interpret	VERB
mkg-56898	37	23	biomarkers	biomarker	NOUN
mkg-56898	37	24	and	and	CCONJ
mkg-56898	37	25	therapeutic	therapeutic	ADJ
mkg-56898	37	26	targets	target	NOUN
mkg-56898	37	27	of	of	ADP
mkg-56898	37	28	pgv-0	pgv-0	NOUN
mkg-56898	37	29	.	.	PUNCT
mkg-56898	38	1	as	as	ADP
mkg-56898	38	2	a	a	DET
mkg-56898	38	3	comparison	comparison	NOUN
mkg-56898	38	4	,	,	PUNCT
mkg-56898	38	5	we	we	PRON
mkg-56898	38	6	also	also	ADV
mkg-56898	38	7	analyze	analyze	VERB
mkg-56898	38	8	diclofenac	diclofenac	ADJ
mkg-56898	38	9	sodium	sodium	NOUN
mkg-56898	38	10	(	(	PUNCT
mkg-56898	38	11	c14h11cl2no2	c14h11cl2no2	NOUN
mkg-56898	38	12	)	)	PUNCT
mkg-56898	38	13	as	as	ADP
mkg-56898	38	14	a	a	DET
mkg-56898	38	15	commonly	commonly	ADV
mkg-56898	38	16	used	use	VERB
mkg-56898	38	17	anti	anti	ADJ
mkg-56898	38	18	-	-	ADJ
mkg-56898	38	19	inflammatory	inflammatory	ADJ
mkg-56898	38	20	and	and	CCONJ
mkg-56898	38	21	curcumin	curcumin	NOUN
mkg-56898	38	22	as	as	ADP
mkg-56898	38	23	the	the	DET
mkg-56898	38	24	analog	analog	NOUN
mkg-56898	38	25	of	of	ADP
mkg-56898	38	26	pgv-0	pgv-0	NOUN
mkg-56898	38	27	.	.	PUNCT
mkg-56898	39	1	based	base	VERB
mkg-56898	39	2	on	on	ADP
mkg-56898	39	3	the	the	DET
mkg-56898	39	4	bioinformatics	bioinformatics	NOUN
mkg-56898	39	5	findings	finding	NOUN
mkg-56898	39	6	,	,	PUNCT
mkg-56898	39	7	we	we	PRON
mkg-56898	39	8	perform	perform	VERB
mkg-56898	39	9	molecular	molecular	ADJ
mkg-56898	39	10	docking	docking	NOUN
mkg-56898	39	11	against	against	ADP
mkg-56898	39	12	several	several	ADJ
mkg-56898	39	13	target	target	NOUN
mkg-56898	39	14	enzymes	enzyme	NOUN
mkg-56898	39	15	involved	involve	VERB
mkg-56898	39	16	in	in	ADP
mkg-56898	39	17	tmj	tmj	PROPN
mkg-56898	39	18	diseases	disease	NOUN
mkg-56898	39	19	to	to	PART
mkg-56898	39	20	confirm	confirm	VERB
mkg-56898	39	21	the	the	DET
mkg-56898	39	22	target	target	NOUN
mkg-56898	39	23	interaction	interaction	NOUN
mkg-56898	39	24	.	.	PUNCT
mkg-56898	40	1	the	the	DET
mkg-56898	40	2	information	information	NOUN
mkg-56898	40	3	from	from	ADP
mkg-56898	40	4	this	this	PRON
mkg-56898	40	5	in	in	ADP
mkg-56898	40	6	silico	silico	NOUN
mkg-56898	40	7	study	study	NOUN
mkg-56898	40	8	provides	provide	VERB
mkg-56898	40	9	a	a	DET
mkg-56898	40	10	scientific	scientific	ADJ
mkg-56898	40	11	basis	basis	NOUN
mkg-56898	40	12	for	for	ADP
mkg-56898	40	13	designing	design	VERB
mkg-56898	40	14	future	future	ADJ
mkg-56898	40	15	research	research	NOUN
mkg-56898	40	16	that	that	PRON
mkg-56898	40	17	involves	involve	VERB
mkg-56898	40	18	an	an	DET
mkg-56898	40	19	in	in	ADP
mkg-56898	40	20	vitro	vitro	NOUN
mkg-56898	40	21	/	/	SYM
mkg-56898	40	22	in	in	ADP
mkg-56898	40	23	vivo	vivo	NOUN
mkg-56898	40	24	approach	approach	NOUN
mkg-56898	40	25	.	.	PUNCT
mkg-56898	41	1	an	an	DET
mkg-56898	41	2	in	in	ADP
mkg-56898	41	3	silico	silico	NOUN
mkg-56898	41	4	method	method	NOUN
mkg-56898	41	5	using	use	VERB
mkg-56898	41	6	the	the	DET
mkg-56898	41	7	molegro	molegro	ADJ
mkg-56898	41	8	virtual	virtual	ADJ
mkg-56898	41	9	docker	docker	PROPN
mkg-56898	41	10	program	program	NOUN
mkg-56898	41	11	was	be	AUX
mkg-56898	41	12	employed	employ	VERB
mkg-56898	41	13	to	to	PART
mkg-56898	41	14	investigate	investigate	VERB
mkg-56898	41	15	the	the	DET
mkg-56898	41	16	anti	anti	ADJ
mkg-56898	41	17	-	-	ADJ
mkg-56898	41	18	inflammatory	inflammatory	ADJ
mkg-56898	41	19	effects	effect	NOUN
mkg-56898	41	20	of	of	ADP
mkg-56898	41	21	curcuminoids	curcuminoid	NOUN
mkg-56898	41	22	,	,	PUNCT
mkg-56898	41	23	turmeric	turmeric	ADJ
mkg-56898	41	24	extracts	extract	NOUN
mkg-56898	41	25	with	with	ADP
mkg-56898	41	26	zinc	zinc	NOUN
mkg-56898	41	27	oxide	oxide	NOUN
mkg-56898	41	28	,	,	PUNCT
mkg-56898	41	29	and	and	CCONJ
mkg-56898	41	30	eugenol	eugenol	NOUN
mkg-56898	41	31	before	before	ADP
mkg-56898	41	32	an	an	DET
mkg-56898	41	33	in	in	ADP
mkg-56898	41	34	vivo	vivo	ADJ
mkg-56898	41	35	experiment.17	experiment.17	NOUN
mkg-56898	41	36	materials	material	NOUN
mkg-56898	41	37	and	and	CCONJ
mkg-56898	41	38	methods	method	NOUN
mkg-56898	41	39	the	the	DET
mkg-56898	41	40	chemical	chemical	NOUN
mkg-56898	41	41	structure	structure	NOUN
mkg-56898	41	42	of	of	ADP
mkg-56898	41	43	pgv-0	pgv-0	PUNCT
mkg-56898	41	44	was	be	AUX
mkg-56898	41	45	represented	represent	VERB
mkg-56898	41	46	using	use	VERB
mkg-56898	41	47	the	the	DET
mkg-56898	41	48	simplified	simplified	ADJ
mkg-56898	41	49	molecular	molecular	ADJ
mkg-56898	41	50	input	input	NOUN
mkg-56898	41	51	line	line	NOUN
mkg-56898	41	52	entry	entry	NOUN
mkg-56898	41	53	system	system	NOUN
mkg-56898	41	54	(	(	PUNCT
mkg-56898	41	55	smiles	smile	NOUN
mkg-56898	41	56	)	)	PUNCT
mkg-56898	41	57	code	code	NOUN
mkg-56898	41	58	as	as	SCONJ
mkg-56898	41	59	follows	follow	VERB
mkg-56898	41	60	:	:	PUNCT
mkg-56898	41	61	coc1	coc1	PROPN
mkg-56898	41	62	=	=	SYM
mkg-56898	41	63	cc(\c	cc(\c	PROPN
mkg-56898	41	64	=	=	PROPN
mkg-56898	41	65	c2	c2	PROPN
mkg-56898	41	66	/	/	SYM
mkg-56898	41	67	cc\c(=c/	cc\c(=c/	PROPN
mkg-56898	41	68	c3	c3	PROPN
mkg-56898	41	69	=	=	PROPN
mkg-56898	41	70	cc(oc)=c(o)c	cc(oc)=c(o)c	PROPN
mkg-56898	41	71	=	=	SYM
mkg-56898	41	72	c)c2	c)c2	PROPN
mkg-56898	41	73	=	=	NOUN
mkg-56898	41	74	o)=cc	o)=cc	NOUN
mkg-56898	41	75	=	=	SYM
mkg-56898	41	76	c1o	c1o	X
mkg-56898	41	77	.	.	PUNCT
mkg-56898	42	1	the	the	DET
mkg-56898	42	2	canonical	canonical	ADJ
mkg-56898	42	3	smiles	smile	NOUN
mkg-56898	42	4	string	string	NOUN
mkg-56898	42	5	was	be	AUX
mkg-56898	42	6	then	then	ADV
mkg-56898	42	7	inputted	inputte	VERB
mkg-56898	42	8	into	into	ADP
mkg-56898	42	9	swisstargetprediction	swisstargetprediction	NOUN
mkg-56898	42	10	,	,	PUNCT
mkg-56898	42	11	restricting	restrict	VERB
mkg-56898	42	12	predictions	prediction	NOUN
mkg-56898	42	13	to	to	ADP
mkg-56898	42	14	human	human	ADJ
mkg-56898	42	15	protein	protein	NOUN
mkg-56898	42	16	targets	target	NOUN
mkg-56898	42	17	.	.	PUNCT
mkg-56898	43	1	bioactive	bioactive	VERB
mkg-56898	43	2	compounds	compound	NOUN
mkg-56898	43	3	with	with	ADP
mkg-56898	43	4	similar	similar	ADJ
mkg-56898	43	5	predicted	predict	VERB
mkg-56898	43	6	targets	target	NOUN
mkg-56898	43	7	as	as	ADP
mkg-56898	43	8	pgv-0	pgv-0	PUNCT
mkg-56898	43	9	were	be	AUX
mkg-56898	43	10	identified	identify	VERB
mkg-56898	43	11	from	from	ADP
mkg-56898	43	12	the	the	DET
mkg-56898	43	13	swisstargetprediction	swisstargetprediction	NOUN
mkg-56898	43	14	program	program	NOUN
mkg-56898	43	15	(	(	PUNCT
mkg-56898	43	16	http://	http://	PROPN
mkg-56898	43	17	www.swisstargetprediction.ch/	www.swisstargetprediction.ch/	PROPN
mkg-56898	43	18	,	,	PUNCT
mkg-56898	43	19	2019	2019	NUM
mkg-56898	43	20	version	version	NOUN
mkg-56898	43	21	)	)	PUNCT
mkg-56898	43	22	,	,	PUNCT
mkg-56898	43	23	along	along	ADP
mkg-56898	43	24	with	with	ADP
mkg-56898	43	25	curcumin	curcumin	NOUN
mkg-56898	43	26	and	and	CCONJ
mkg-56898	43	27	diclofenac	diclofenac	ADJ
mkg-56898	43	28	sodium	sodium	NOUN
mkg-56898	43	29	as	as	ADP
mkg-56898	43	30	reference	reference	NOUN
mkg-56898	43	31	compounds	compound	NOUN
mkg-56898	43	32	.	.	PUNCT
mkg-56898	44	1	we	we	PRON
mkg-56898	44	2	identified	identify	VERB
mkg-56898	44	3	potential	potential	ADJ
mkg-56898	44	4	targets	target	NOUN
mkg-56898	44	5	by	by	ADP
mkg-56898	44	6	searching	search	VERB
mkg-56898	44	7	for	for	ADP
mkg-56898	44	8	“	"	PUNCT
mkg-56898	44	9	temporomandibular	temporomandibular	ADJ
mkg-56898	44	10	arthritis	arthritis	NOUN
mkg-56898	44	11	”	"	PUNCT
mkg-56898	44	12	in	in	ADP
mkg-56898	44	13	genecards	genecard	NOUN
mkg-56898	44	14	(	(	PUNCT
mkg-56898	44	15	https://www	https://www	PROPN
mkg-56898	44	16	.	.	PROPN
mkg-56898	44	17	genecards.org/	genecards.org/	PROPN
mkg-56898	44	18	)	)	PUNCT
mkg-56898	44	19	,	,	PUNCT
mkg-56898	44	20	which	which	PRON
mkg-56898	44	21	provides	provide	VERB
mkg-56898	44	22	comprehensive	comprehensive	ADJ
mkg-56898	44	23	molecular	molecular	ADJ
mkg-56898	44	24	information	information	NOUN
mkg-56898	44	25	about	about	ADP
mkg-56898	44	26	drugs	drug	NOUN
mkg-56898	44	27	,	,	PUNCT
mkg-56898	44	28	targets	target	NOUN
mkg-56898	44	29	,	,	PUNCT
mkg-56898	44	30	disease	disease	NOUN
mkg-56898	44	31	-	-	PUNCT
mkg-56898	44	32	related	relate	VERB
mkg-56898	44	33	genes	gene	NOUN
mkg-56898	44	34	,	,	PUNCT
mkg-56898	44	35	and	and	CCONJ
mkg-56898	44	36	gene	gene	NOUN
mkg-56898	44	37	function	function	NOUN
mkg-56898	44	38	.	.	PUNCT
mkg-56898	45	1	we	we	PRON
mkg-56898	45	2	selected	select	VERB
mkg-56898	45	3	the	the	DET
mkg-56898	45	4	top	top	ADJ
mkg-56898	45	5	321	321	NUM
mkg-56898	45	6	genes	gene	NOUN
mkg-56898	45	7	generated	generate	VERB
mkg-56898	45	8	in	in	ADP
mkg-56898	45	9	genecards	genecard	NOUN
mkg-56898	45	10	.	.	PUNCT
mkg-56898	46	1	a	a	DET
mkg-56898	46	2	venn	venn	PROPN
mkg-56898	46	3	diagram	diagram	PROPN
mkg-56898	46	4	was	be	AUX
mkg-56898	46	5	created	create	VERB
mkg-56898	46	6	to	to	PART
mkg-56898	46	7	determine	determine	VERB
mkg-56898	46	8	the	the	DET
mkg-56898	46	9	overlap	overlap	NOUN
mkg-56898	46	10	between	between	ADP
mkg-56898	46	11	the	the	DET
mkg-56898	46	12	potential	potential	ADJ
mkg-56898	46	13	targets	target	NOUN
mkg-56898	46	14	of	of	ADP
mkg-56898	46	15	each	each	DET
mkg-56898	46	16	compound	compound	NOUN
mkg-56898	46	17	and	and	CCONJ
mkg-56898	46	18	the	the	DET
mkg-56898	46	19	genes	gene	NOUN
mkg-56898	46	20	expressed	express	VERB
mkg-56898	46	21	in	in	ADP
mkg-56898	46	22	arthritis	arthritis	NOUN
mkg-56898	46	23	.	.	PUNCT
mkg-56898	47	1	the	the	DET
mkg-56898	47	2	overlaps	overlap	NOUN
mkg-56898	47	3	were	be	AUX
mkg-56898	47	4	identified	identify	VERB
mkg-56898	47	5	as	as	ADP
mkg-56898	47	6	potential	potential	ADJ
mkg-56898	47	7	targets	target	NOUN
mkg-56898	47	8	.	.	PUNCT
mkg-56898	48	1	the	the	DET
mkg-56898	48	2	interaction	interaction	NOUN
mkg-56898	48	3	landscape	landscape	NOUN
mkg-56898	48	4	between	between	ADP
mkg-56898	48	5	the	the	DET
mkg-56898	48	6	overlapping	overlap	VERB
mkg-56898	48	7	genes	gene	NOUN
mkg-56898	48	8	of	of	ADP
mkg-56898	48	9	temporomandibular	temporomandibular	ADJ
mkg-56898	48	10	arthritis	arthritis	NOUN
mkg-56898	48	11	and	and	CCONJ
mkg-56898	48	12	the	the	DET
mkg-56898	48	13	molecular	molecular	ADJ
mkg-56898	48	14	targets	target	NOUN
mkg-56898	48	15	of	of	ADP
mkg-56898	48	16	pgv-0	pgv-0	NOUN
mkg-56898	48	17	,	,	PUNCT
mkg-56898	48	18	curcumin	curcumin	NOUN
mkg-56898	48	19	,	,	PUNCT
mkg-56898	48	20	and	and	CCONJ
mkg-56898	48	21	diclofenac	diclofenac	ADJ
mkg-56898	48	22	sodium	sodium	NOUN
mkg-56898	48	23	was	be	AUX
mkg-56898	48	24	constructed	construct	VERB
mkg-56898	48	25	using	use	VERB
mkg-56898	48	26	the	the	DET
mkg-56898	48	27	search	search	NOUN
mkg-56898	48	28	tool	tool	NOUN
mkg-56898	48	29	for	for	ADP
mkg-56898	48	30	the	the	DET
mkg-56898	48	31	retrieval	retrieval	NOUN
mkg-56898	48	32	of	of	ADP
mkg-56898	48	33	interacting	interact	VERB
mkg-56898	48	34	genes/	genes/	NUM
mkg-56898	48	35	proteins	protein	NOUN
mkg-56898	48	36	(	(	PUNCT
mkg-56898	48	37	string	string	NOUN
mkg-56898	48	38	)	)	PUNCT
mkg-56898	48	39	database	database	NOUN
mkg-56898	48	40	(	(	PUNCT
mkg-56898	48	41	version	version	NOUN
mkg-56898	48	42	11.0b	11.0b	NUM
mkg-56898	48	43	)	)	PUNCT
mkg-56898	48	44	.	.	PUNCT
mkg-56898	49	1	the	the	DET
mkg-56898	49	2	required	require	VERB
mkg-56898	49	3	confidence	confidence	NOUN
mkg-56898	49	4	score	score	NOUN
mkg-56898	49	5	was	be	AUX
mkg-56898	49	6	set	set	VERB
mkg-56898	49	7	at	at	ADP
mkg-56898	49	8	0.700	0.700	NUM
mkg-56898	49	9	(	(	PUNCT
mkg-56898	49	10	high	high	ADJ
mkg-56898	49	11	confidence	confidence	NOUN
mkg-56898	49	12	)	)	PUNCT
mkg-56898	49	13	.	.	PUNCT
mkg-56898	50	1	active	active	ADJ
mkg-56898	50	2	interaction	interaction	NOUN
mkg-56898	50	3	sources	source	NOUN
mkg-56898	50	4	included	include	VERB
mkg-56898	50	5	text	text	NOUN
mkg-56898	50	6	mining	mining	NOUN
mkg-56898	50	7	,	,	PUNCT
mkg-56898	50	8	experiments	experiment	NOUN
mkg-56898	50	9	,	,	PUNCT
mkg-56898	50	10	databases	database	NOUN
mkg-56898	50	11	,	,	PUNCT
mkg-56898	50	12	co	co	NOUN
mkg-56898	50	13	-	-	NOUN
mkg-56898	50	14	expression	expression	NOUN
mkg-56898	50	15	,	,	PUNCT
mkg-56898	50	16	neighborhood	neighborhood	NOUN
mkg-56898	50	17	,	,	PUNCT
mkg-56898	50	18	gene	gene	NOUN
mkg-56898	50	19	fusion	fusion	NOUN
mkg-56898	50	20	,	,	PUNCT
mkg-56898	50	21	and	and	CCONJ
mkg-56898	50	22	co	co	NOUN
mkg-56898	50	23	-	-	NOUN
mkg-56898	50	24	occurrence	occurrence	NOUN
mkg-56898	50	25	.	.	PUNCT
mkg-56898	51	1	the	the	DET
mkg-56898	51	2	molecular	molecular	ADJ
mkg-56898	51	3	action	action	NOUN
mkg-56898	51	4	view	view	NOUN
mkg-56898	51	5	visualized	visualize	VERB
mkg-56898	51	6	the	the	DET
mkg-56898	51	7	predicted	predict	VERB
mkg-56898	51	8	associations	association	NOUN
mkg-56898	51	9	.	.	PUNCT
mkg-56898	52	1	we	we	PRON
mkg-56898	52	2	examined	examine	VERB
mkg-56898	52	3	the	the	DET
mkg-56898	52	4	upstream	upstream	ADJ
mkg-56898	52	5	and	and	CCONJ
mkg-56898	52	6	downstream	downstream	ADJ
mkg-56898	52	7	genes	gene	NOUN
mkg-56898	52	8	of	of	ADP
mkg-56898	52	9	the	the	DET
mkg-56898	52	10	main	main	ADJ
mkg-56898	52	11	signaling	signal	VERB
mkg-56898	52	12	pathways	pathway	NOUN
mkg-56898	52	13	that	that	PRON
mkg-56898	52	14	link	link	VERB
mkg-56898	52	15	pgv-0	pgv-0	NOUN
mkg-56898	52	16	,	,	PUNCT
mkg-56898	52	17	curcumin	curcumin	NOUN
mkg-56898	52	18	,	,	PUNCT
mkg-56898	52	19	and	and	CCONJ
mkg-56898	52	20	diclofenac	diclofenac	ADJ
mkg-56898	52	21	sodium	sodium	NOUN
mkg-56898	52	22	to	to	ADP
mkg-56898	52	23	temporomandibular	temporomandibular	ADJ
mkg-56898	52	24	arthritis	arthritis	NOUN
mkg-56898	52	25	using	use	VERB
mkg-56898	52	26	the	the	DET
mkg-56898	52	27	gene	gene	NOUN
mkg-56898	52	28	ontology	ontology	NOUN
mkg-56898	52	29	(	(	PUNCT
mkg-56898	52	30	go	go	VERB
mkg-56898	52	31	)	)	PUNCT
mkg-56898	52	32	panther	panther	NOUN
mkg-56898	52	33	mapper	mapper	NOUN
mkg-56898	52	34	system	system	NOUN
mkg-56898	52	35	(	(	PUNCT
mkg-56898	52	36	https://www.genome.jp/kegg/mapper.html	https://www.genome.jp/kegg/mapper.html	PROPN
mkg-56898	52	37	)	)	PUNCT
mkg-56898	52	38	.	.	PUNCT
mkg-56898	53	1	furthermore	furthermore	ADV
mkg-56898	53	2	,	,	PUNCT
mkg-56898	53	3	we	we	PRON
mkg-56898	53	4	used	use	VERB
mkg-56898	53	5	the	the	DET
mkg-56898	53	6	kyoto	kyoto	PROPN
mkg-56898	53	7	encyclopedia	encyclopedia	NOUN
mkg-56898	53	8	of	of	ADP
mkg-56898	53	9	genes	gene	NOUN
mkg-56898	53	10	and	and	CCONJ
mkg-56898	53	11	genomes	genome	NOUN
mkg-56898	53	12	(	(	PUNCT
mkg-56898	53	13	kegg	kegg	NOUN
mkg-56898	53	14	)	)	PUNCT
mkg-56898	53	15	pathway	pathway	NOUN
mkg-56898	53	16	database	database	NOUN
mkg-56898	53	17	to	to	PART
mkg-56898	53	18	present	present	VERB
mkg-56898	53	19	our	our	PRON
mkg-56898	53	20	knowledge	knowledge	NOUN
mkg-56898	53	21	of	of	ADP
mkg-56898	53	22	the	the	DET
mkg-56898	53	23	molecular	molecular	ADJ
mkg-56898	53	24	interaction	interaction	NOUN
mkg-56898	53	25	,	,	PUNCT
mkg-56898	53	26	reaction	reaction	NOUN
mkg-56898	53	27	,	,	PUNCT
mkg-56898	53	28	and	and	CCONJ
mkg-56898	53	29	relationship	relationship	NOUN
mkg-56898	53	30	networks	network	NOUN
mkg-56898	53	31	for	for	ADP
mkg-56898	53	32	metabolism	metabolism	NOUN
mkg-56898	53	33	,	,	PUNCT
mkg-56898	53	34	genetic	genetic	ADJ
mkg-56898	53	35	information	information	NOUN
mkg-56898	53	36	processing	processing	NOUN
mkg-56898	53	37	,	,	PUNCT
mkg-56898	53	38	and	and	CCONJ
mkg-56898	53	39	cellular	cellular	ADJ
mkg-56898	53	40	processes	process	NOUN
mkg-56898	53	41	of	of	ADP
mkg-56898	53	42	pgv-0	pgv-0	PUNCT
mkg-56898	53	43	and	and	CCONJ
mkg-56898	53	44	temporomandibular	temporomandibular	ADJ
mkg-56898	53	45	arthritis	arthritis	NOUN
mkg-56898	53	46	.	.	PUNCT
mkg-56898	54	1	this	this	PRON
mkg-56898	54	2	was	be	AUX
mkg-56898	54	3	performed	perform	VERB
mkg-56898	54	4	to	to	PART
mkg-56898	54	5	identify	identify	VERB
mkg-56898	54	6	the	the	DET
mkg-56898	54	7	top	top	ADJ
mkg-56898	54	8	10	10	NUM
mkg-56898	54	9	pathways	pathway	NOUN
mkg-56898	54	10	most	most	ADV
mkg-56898	54	11	influenced	influence	VERB
mkg-56898	54	12	.	.	PUNCT
mkg-56898	55	1	we	we	PRON
mkg-56898	55	2	used	use	VERB
mkg-56898	55	3	webgestalt18	webgestalt18	NOUN
mkg-56898	55	4	(	(	PUNCT
mkg-56898	55	5	http://www.webgestalt	http://www.webgestalt	PROPN
mkg-56898	55	6	.	.	PUNCT
mkg-56898	55	7	org/	org/	PROPN
mkg-56898	55	8	)	)	PUNCT
mkg-56898	55	9	and	and	CCONJ
mkg-56898	55	10	selected	select	VERB
mkg-56898	55	11	overrepresentation	overrepresentation	NOUN
mkg-56898	55	12	enrichment	enrichment	NOUN
mkg-56898	55	13	analysis	analysis	NOUN
mkg-56898	55	14	(	(	PUNCT
mkg-56898	55	15	ora	ora	NOUN
mkg-56898	55	16	)	)	PUNCT
mkg-56898	55	17	for	for	ADP
mkg-56898	55	18	the	the	DET
mkg-56898	55	19	enrichment	enrichment	NOUN
mkg-56898	55	20	analysis	analysis	NOUN
mkg-56898	55	21	using	use	VERB
mkg-56898	55	22	the	the	DET
mkg-56898	55	23	kegg	kegg	NOUN
mkg-56898	55	24	pathway	pathway	NOUN
mkg-56898	55	25	database	database	NOUN
mkg-56898	55	26	and	and	CCONJ
mkg-56898	55	27	functional	functional	ADJ
mkg-56898	55	28	annotation	annotation	NOUN
mkg-56898	55	29	terms	term	NOUN
mkg-56898	55	30	using	use	VERB
mkg-56898	55	31	go	go	VERB
mkg-56898	55	32	databases	database	NOUN
mkg-56898	55	33	(	(	PUNCT
mkg-56898	55	34	false	false	ADJ
mkg-56898	55	35	discovery	discovery	NOUN
mkg-56898	55	36	rate	rate	NOUN
mkg-56898	55	37	<	<	NOUN
mkg-56898	55	38	0.05	0.05	NUM
mkg-56898	55	39	was	be	AUX
mkg-56898	55	40	selected	select	VERB
mkg-56898	55	41	as	as	ADP
mkg-56898	55	42	the	the	DET
mkg-56898	55	43	threshold	threshold	NOUN
mkg-56898	55	44	)	)	PUNCT
mkg-56898	55	45	.	.	PUNCT
mkg-56898	56	1	we	we	PRON
mkg-56898	56	2	used	use	VERB
mkg-56898	56	3	the	the	DET
mkg-56898	56	4	molecular	molecular	ADJ
mkg-56898	56	5	operating	operating	NOUN
mkg-56898	56	6	environment	environment	NOUN
mkg-56898	56	7	(	(	PUNCT
mkg-56898	56	8	moe	moe	NOUN
mkg-56898	56	9	)	)	PUNCT
mkg-56898	56	10	program	program	NOUN
mkg-56898	56	11	(	(	PUNCT
mkg-56898	56	12	version	version	NOUN
mkg-56898	56	13	2010.12	2010.12	NUM
mkg-56898	56	14	)	)	PUNCT
mkg-56898	56	15	with	with	ADP
mkg-56898	56	16	default	default	NOUN
mkg-56898	56	17	settings	setting	NOUN
mkg-56898	56	18	to	to	PART
mkg-56898	56	19	generate	generate	VERB
mkg-56898	56	20	the	the	DET
mkg-56898	56	21	molecular	molecular	ADJ
mkg-56898	56	22	interactions	interaction	NOUN
mkg-56898	56	23	between	between	ADP
mkg-56898	56	24	the	the	DET
mkg-56898	56	25	ligand	ligand	NOUN
mkg-56898	56	26	and	and	CCONJ
mkg-56898	56	27	receptor	receptor	NOUN
mkg-56898	56	28	(	(	PUNCT
mkg-56898	56	29	unless	unless	SCONJ
mkg-56898	56	30	stated	state	VERB
mkg-56898	56	31	otherwise	otherwise	ADV
mkg-56898	56	32	)	)	PUNCT
mkg-56898	56	33	.	.	PUNCT
mkg-56898	57	1	the	the	DET
mkg-56898	57	2	structure	structure	NOUN
mkg-56898	57	3	of	of	ADP
mkg-56898	57	4	diclofenac	diclofenac	ADJ
mkg-56898	57	5	sodium	sodium	NOUN
mkg-56898	57	6	,	,	PUNCT
mkg-56898	57	7	curcumin	curcumin	NOUN
mkg-56898	57	8	,	,	PUNCT
mkg-56898	57	9	and	and	CCONJ
mkg-56898	57	10	pgv-0	pgv-0	PUNCT
mkg-56898	57	11	was	be	AUX
mkg-56898	57	12	drawn	draw	VERB
mkg-56898	57	13	using	use	VERB
mkg-56898	57	14	the	the	DET
mkg-56898	57	15	program	program	NOUN
mkg-56898	57	16	’s	’s	PART
mkg-56898	57	17	compound	compound	NOUN
mkg-56898	57	18	builder	builder	NOUN
mkg-56898	57	19	.	.	PUNCT
mkg-56898	58	1	the	the	DET
mkg-56898	58	2	conformational	conformational	ADJ
mkg-56898	58	3	structure	structure	NOUN
mkg-56898	58	4	was	be	AUX
mkg-56898	58	5	then	then	ADV
mkg-56898	58	6	explored	explore	VERB
mkg-56898	58	7	.	.	PUNCT
mkg-56898	59	1	mitogen	mitogen	NOUN
mkg-56898	59	2	-	-	PUNCT
mkg-56898	59	3	activated	activate	VERB
mkg-56898	59	4	protein	protein	NOUN
mkg-56898	59	5	kinase-1	kinase-1	PROPN
mkg-56898	59	6	(	(	PUNCT
mkg-56898	59	7	mapk-1	mapk-1	NUM
mkg-56898	59	8	,	,	PUNCT
mkg-56898	59	9	pdb	pdb	NOUN
mkg-56898	59	10	-	-	ADJ
mkg-56898	59	11	id	id	ADJ
mkg-56898	59	12	:	:	PUNCT
mkg-56898	59	13	5bvd	5bvd	NUM
mkg-56898	59	14	)	)	PUNCT
mkg-56898	59	15	,	,	PUNCT
mkg-56898	59	16	matrix	matrix	NOUN
mkg-56898	59	17	metallopeptidase	metallopeptidase	NOUN
mkg-56898	59	18	13	13	NUM
mkg-56898	59	19	(	(	PUNCT
mkg-56898	59	20	mmp-13	mmp-13	PROPN
mkg-56898	59	21	,	,	PUNCT
mkg-56898	59	22	pdb	pdb	NOUN
mkg-56898	59	23	-	-	ADJ
mkg-56898	59	24	id	id	ADP
mkg-56898	59	25	:	:	PUNCT
mkg-56898	59	26	4jpa	4jpa	NUM
mkg-56898	59	27	)	)	PUNCT
mkg-56898	59	28	,	,	PUNCT
mkg-56898	59	29	cyclooxygenase-1	cyclooxygenase-1	PROPN
mkg-56898	59	30	(	(	PUNCT
mkg-56898	59	31	cox-1	cox-1	X
mkg-56898	59	32	,	,	PUNCT
mkg-56898	59	33	pdb	pdb	PROPN
mkg-56898	59	34	-	-	ADJ
mkg-56898	59	35	id	id	ADJ
mkg-56898	59	36	:	:	PUNCT
mkg-56898	59	37	5wbe	5wbe	NUM
mkg-56898	59	38	)	)	PUNCT
mkg-56898	59	39	,	,	PUNCT
mkg-56898	59	40	and	and	CCONJ
mkg-56898	59	41	cyclooxygenase-2	cyclooxygenase-2	NUM
mkg-56898	59	42	(	(	PUNCT
mkg-56898	59	43	cox-2	cox-2	NOUN
mkg-56898	59	44	,	,	PUNCT
mkg-56898	59	45	pdb	pdb	NOUN
mkg-56898	59	46	-	-	ADJ
mkg-56898	59	47	id	id	ADJ
mkg-56898	59	48	:	:	PUNCT
mkg-56898	59	49	3ln1	3ln1	NUM
mkg-56898	59	50	)	)	PUNCT
mkg-56898	59	51	were	be	AUX
mkg-56898	59	52	chosen	choose	VERB
mkg-56898	59	53	as	as	ADP
mkg-56898	59	54	the	the	DET
mkg-56898	59	55	protein	protein	NOUN
mkg-56898	59	56	targets	target	NOUN
mkg-56898	59	57	in	in	ADP
mkg-56898	59	58	this	this	DET
mkg-56898	59	59	study	study	NOUN
mkg-56898	59	60	.	.	PUNCT
mkg-56898	60	1	the	the	DET
mkg-56898	60	2	docking	docking	NOUN
mkg-56898	60	3	protocol	protocol	NOUN
mkg-56898	60	4	of	of	ADP
mkg-56898	60	5	hasbiyani	hasbiyani	PROPN
mkg-56898	60	6	et	et	PROPN
mkg-56898	60	7	al	al	PROPN
mkg-56898	60	8	.	.	PROPN
mkg-56898	60	9	(	(	PUNCT
mkg-56898	60	10	2021	2021	NUM
mkg-56898	60	11	)	)	PUNCT
mkg-56898	60	12	was	be	AUX
mkg-56898	60	13	followed	follow	VERB
mkg-56898	60	14	.	.	PUNCT
mkg-56898	61	1	the	the	DET
mkg-56898	61	2	ligand	ligand	ADJ
mkg-56898	61	3	conformation	conformation	NOUN
mkg-56898	61	4	with	with	ADP
mkg-56898	61	5	the	the	DET
mkg-56898	61	6	lowest	low	ADJ
mkg-56898	61	7	docking	docking	NOUN
mkg-56898	61	8	score	score	NOUN
mkg-56898	61	9	was	be	AUX
mkg-56898	61	10	analyzed	analyze	VERB
mkg-56898	61	11	for	for	ADP
mkg-56898	61	12	the	the	DET
mkg-56898	61	13	binding	bind	VERB
mkg-56898	61	14	interaction.19	interaction.19	NOUN
mkg-56898	61	15	copyright	copyright	NOUN
mkg-56898	61	16	©	©	ADP
mkg-56898	61	17	2025	2025	NUM
mkg-56898	61	18	dental	dental	ADJ
mkg-56898	61	19	journal	journal	NOUN
mkg-56898	61	20	(	(	PUNCT
mkg-56898	61	21	majalah	majalah	PROPN
mkg-56898	61	22	kedokteran	kedokteran	PROPN
mkg-56898	61	23	gigi	gigi	PROPN
mkg-56898	61	24	)	)	PUNCT
mkg-56898	61	25	p	p	X
mkg-56898	61	26	-	-	PUNCT
mkg-56898	61	27	issn	issn	NOUN
mkg-56898	61	28	:	:	PUNCT
mkg-56898	61	29	1978	1978	NUM
mkg-56898	61	30	-	-	SYM
mkg-56898	61	31	3728	3728	NUM
mkg-56898	61	32	;	;	PUNCT
mkg-56898	61	33	e	e	X
mkg-56898	61	34	-	-	PUNCT
mkg-56898	61	35	issn	issn	ADJ
mkg-56898	61	36	:	:	PUNCT
mkg-56898	61	37	2442	2442	NUM
mkg-56898	61	38	-	-	SYM
mkg-56898	61	39	9740	9740	NUM
mkg-56898	61	40	.	.	PUNCT
mkg-56898	62	1	accredited	accredit	VERB
mkg-56898	62	2	no	no	INTJ
mkg-56898	62	3	.	.	PROPN
mkg-56898	63	1	158	158	NUM
mkg-56898	63	2	/	/	SYM
mkg-56898	63	3	e	e	NOUN
mkg-56898	63	4	/	/	SYM
mkg-56898	63	5	kpt/2021	kpt/2021	NOUN
mkg-56898	63	6	.	.	PUNCT
mkg-56898	64	1	open	open	ADJ
mkg-56898	64	2	access	access	NOUN
mkg-56898	64	3	under	under	ADP
mkg-56898	64	4	cc	cc	NOUN
mkg-56898	64	5	-	-	PUNCT
mkg-56898	64	6	by	by	ADP
mkg-56898	64	7	-	-	PUNCT
mkg-56898	64	8	sa	sa	NOUN
mkg-56898	64	9	license	license	NOUN
mkg-56898	64	10	.	.	PUNCT
mkg-56898	65	1	available	available	ADJ
mkg-56898	65	2	at	at	ADP
mkg-56898	65	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	65	4	doi	doi	NOUN
mkg-56898	65	5	:	:	PUNCT
mkg-56898	65	6	10.20473	10.20473	NUM
mkg-56898	65	7	/	/	SYM
mkg-56898	65	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	NOUN
mkg-56898	65	9	http://www.swisstargetprediction.ch/	http://www.swisstargetprediction.ch/	VERB
mkg-56898	65	10	https://www	https://www	PROPN
mkg-56898	65	11	https://www.genome.jp/kegg/mapper.html	https://www.genome.jp/kegg/mapper.html	VERB
mkg-56898	65	12	http://www.webgestalt	http://www.webgestalt	PROPN
mkg-56898	65	13	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	PROPN
mkg-56898	65	14	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	PROPN
mkg-56898	66	1	369robin	369robin	PROPN
mkg-56898	66	2	et	et	PROPN
mkg-56898	66	3	al	al	PROPN
mkg-56898	66	4	.	.	PROPN
mkg-56898	66	5	dent	dent	PROPN
mkg-56898	66	6	.	.	PUNCT
mkg-56898	67	1	j.	j.	PROPN
mkg-56898	67	2	(	(	PUNCT
mkg-56898	67	3	majalah	majalah	PROPN
mkg-56898	67	4	kedokteran	kedokteran	PROPN
mkg-56898	67	5	gigi	gigi	PROPN
mkg-56898	67	6	)	)	PUNCT
mkg-56898	67	7	2025	2025	NUM
mkg-56898	67	8	december	december	NOUN
mkg-56898	67	9	;	;	PUNCT
mkg-56898	67	10	58(4	58(4	NUM
mkg-56898	67	11	):	):	PUNCT
mkg-56898	67	12	367–375	367–375	NUM
mkg-56898	67	13	results	result	NOUN
mkg-56898	67	14	initially	initially	ADV
mkg-56898	67	15	,	,	PUNCT
mkg-56898	67	16	we	we	PRON
mkg-56898	67	17	identified	identify	VERB
mkg-56898	67	18	a	a	DET
mkg-56898	67	19	total	total	NOUN
mkg-56898	67	20	of	of	ADP
mkg-56898	67	21	321	321	NUM
mkg-56898	67	22	genes	gene	NOUN
mkg-56898	67	23	associated	associate	VERB
mkg-56898	67	24	with	with	ADP
mkg-56898	67	25	temporomandibular	temporomandibular	ADJ
mkg-56898	67	26	arthritis	arthritis	NOUN
mkg-56898	67	27	from	from	ADP
mkg-56898	67	28	the	the	DET
mkg-56898	67	29	genecards	genecard	NOUN
mkg-56898	67	30	database	database	NOUN
mkg-56898	67	31	.	.	PUNCT
mkg-56898	68	1	following	follow	VERB
mkg-56898	68	2	this	this	PRON
mkg-56898	68	3	,	,	PUNCT
mkg-56898	68	4	the	the	DET
mkg-56898	68	5	potential	potential	ADJ
mkg-56898	68	6	targets	target	NOUN
mkg-56898	68	7	of	of	ADP
mkg-56898	68	8	the	the	DET
mkg-56898	68	9	intended	intend	VERB
mkg-56898	68	10	compounds	compound	NOUN
mkg-56898	68	11	were	be	AUX
mkg-56898	68	12	retrieved	retrieve	VERB
mkg-56898	68	13	from	from	ADP
mkg-56898	68	14	swisstargetprediction	swisstargetprediction	NOUN
mkg-56898	68	15	,	,	PUNCT
mkg-56898	68	16	resulting	result	VERB
mkg-56898	68	17	in	in	ADP
mkg-56898	68	18	58	58	NUM
mkg-56898	68	19	genes	gene	NOUN
mkg-56898	68	20	related	relate	VERB
mkg-56898	68	21	to	to	PART
mkg-56898	68	22	diclofenac	diclofenac	VERB
mkg-56898	68	23	sodium	sodium	NOUN
mkg-56898	68	24	and	and	CCONJ
mkg-56898	68	25	100	100	NUM
mkg-56898	68	26	genes	gene	NOUN
mkg-56898	68	27	for	for	ADP
mkg-56898	68	28	each	each	PRON
mkg-56898	68	29	of	of	ADP
mkg-56898	68	30	curcumin	curcumin	NOUN
mkg-56898	68	31	and	and	CCONJ
mkg-56898	68	32	pgv-0	pgv-0	NOUN
mkg-56898	68	33	.	.	PUNCT
mkg-56898	69	1	from	from	ADP
mkg-56898	69	2	the	the	DET
mkg-56898	69	3	obtained	obtain	VERB
mkg-56898	69	4	data	datum	NOUN
mkg-56898	69	5	,	,	PUNCT
mkg-56898	69	6	we	we	PRON
mkg-56898	69	7	described	describe	VERB
mkg-56898	69	8	the	the	DET
mkg-56898	69	9	logical	logical	ADJ
mkg-56898	69	10	relationships	relationship	NOUN
mkg-56898	69	11	between	between	ADP
mkg-56898	69	12	the	the	DET
mkg-56898	69	13	finite	finite	ADJ
mkg-56898	69	14	sets	set	NOUN
mkg-56898	69	15	of	of	ADP
mkg-56898	69	16	genes	gene	NOUN
mkg-56898	69	17	associated	associate	VERB
mkg-56898	69	18	with	with	ADP
mkg-56898	69	19	temporomandibular	temporomandibular	ADJ
mkg-56898	69	20	arthritis	arthritis	NOUN
mkg-56898	69	21	,	,	PUNCT
mkg-56898	69	22	diclofenac	diclofenac	NOUN
mkg-56898	69	23	sodium	sodium	NOUN
mkg-56898	69	24	,	,	PUNCT
mkg-56898	69	25	curcumin	curcumin	NOUN
mkg-56898	69	26	,	,	PUNCT
mkg-56898	69	27	and	and	CCONJ
mkg-56898	69	28	pgv-0	pgv-0	PUNCT
mkg-56898	69	29	in	in	ADP
mkg-56898	69	30	venn	venn	PROPN
mkg-56898	69	31	diagrams	diagram	NOUN
mkg-56898	69	32	(	(	PUNCT
mkg-56898	69	33	figure	figure	NOUN
mkg-56898	69	34	1	1	NUM
mkg-56898	69	35	)	)	PUNCT
mkg-56898	69	36	.	.	PUNCT
mkg-56898	70	1	the	the	DET
mkg-56898	70	2	venn	venn	PROPN
mkg-56898	70	3	diagram	diagram	PROPN
mkg-56898	70	4	intersection	intersection	NOUN
mkg-56898	70	5	ruled	rule	VERB
mkg-56898	70	6	out	out	ADP
mkg-56898	70	7	8	8	NUM
mkg-56898	70	8	genes	gene	NOUN
mkg-56898	70	9	as	as	ADP
mkg-56898	70	10	targets	target	NOUN
mkg-56898	70	11	of	of	ADP
mkg-56898	70	12	diclofenac	diclofenac	ADJ
mkg-56898	70	13	sodium	sodium	NOUN
mkg-56898	70	14	and	and	CCONJ
mkg-56898	70	15	6	6	NUM
mkg-56898	70	16	genes	gene	NOUN
mkg-56898	70	17	as	as	ADP
mkg-56898	70	18	targets	target	NOUN
mkg-56898	70	19	of	of	ADP
mkg-56898	70	20	curcumin	curcumin	NOUN
mkg-56898	70	21	and	and	CCONJ
mkg-56898	70	22	pgv-0	pgv-0	PUNCT
mkg-56898	70	23	in	in	ADP
mkg-56898	70	24	temporomandibular	temporomandibular	ADJ
mkg-56898	70	25	arthritis	arthritis	NOUN
mkg-56898	70	26	.	.	PUNCT
mkg-56898	71	1	the	the	DET
mkg-56898	71	2	common	common	ADJ
mkg-56898	71	3	target	target	NOUN
mkg-56898	71	4	shared	share	VERB
mkg-56898	71	5	by	by	ADP
mkg-56898	71	6	diclofenac	diclofenac	NOUN
mkg-56898	71	7	sodium	sodium	NOUN
mkg-56898	71	8	,	,	PUNCT
mkg-56898	71	9	curcumin	curcumin	NOUN
mkg-56898	71	10	,	,	PUNCT
mkg-56898	71	11	and	and	CCONJ
mkg-56898	71	12	pgv-0	pgv-0	PUNCT
mkg-56898	71	13	is	be	AUX
mkg-56898	71	14	ptgs1	ptgs1	NOUN
mkg-56898	71	15	,	,	PUNCT
mkg-56898	71	16	which	which	PRON
mkg-56898	71	17	encodes	encode	VERB
mkg-56898	71	18	the	the	DET
mkg-56898	71	19	cox-1	cox-1	ADJ
mkg-56898	71	20	enzyme	enzyme	NOUN
mkg-56898	71	21	.	.	PUNCT
mkg-56898	71	22	cox-1	cox-1	PUNCT
mkg-56898	71	23	catalyzes	catalyze	VERB
mkg-56898	71	24	the	the	DET
mkg-56898	71	25	first	first	ADJ
mkg-56898	71	26	step	step	NOUN
mkg-56898	71	27	in	in	ADP
mkg-56898	71	28	synthesizing	synthesize	VERB
mkg-56898	71	29	prostaglandins	prostaglandin	NOUN
mkg-56898	71	30	from	from	ADP
mkg-56898	71	31	arachidonic	arachidonic	ADJ
mkg-56898	71	32	acid	acid	NOUN
mkg-56898	71	33	.	.	PUNCT
mkg-56898	72	1	initial	initial	ADJ
mkg-56898	72	2	perspectives	perspective	NOUN
mkg-56898	72	3	viewed	view	VERB
mkg-56898	72	4	ptgs1	ptgs1	NOUN
mkg-56898	72	5	as	as	ADP
mkg-56898	72	6	a	a	DET
mkg-56898	72	7	constitutively	constitutively	ADV
mkg-56898	72	8	expressed	express	VERB
mkg-56898	72	9	housekeeping	housekeeping	NOUN
mkg-56898	72	10	gene	gene	NOUN
mkg-56898	72	11	,	,	PUNCT
mkg-56898	72	12	in	in	ADP
mkg-56898	72	13	contrast	contrast	NOUN
mkg-56898	72	14	to	to	ADP
mkg-56898	72	15	the	the	DET
mkg-56898	72	16	inducible	inducible	ADJ
mkg-56898	72	17	ptgs2	ptgs2	NOUN
mkg-56898	72	18	(	(	PUNCT
mkg-56898	72	19	cox-2	cox-2	NOUN
mkg-56898	72	20	)	)	PUNCT
mkg-56898	72	21	enzyme	enzyme	NOUN
mkg-56898	72	22	,	,	PUNCT
mkg-56898	72	23	which	which	PRON
mkg-56898	72	24	mediates	mediate	VERB
mkg-56898	72	25	pathological	pathological	ADJ
mkg-56898	72	26	inflammatory	inflammatory	ADJ
mkg-56898	72	27	responses.20	responses.20	NOUN
mkg-56898	72	28	while	while	SCONJ
mkg-56898	72	29	ptgs2	ptgs2	PROPN
mkg-56898	72	30	has	have	AUX
mkg-56898	72	31	been	be	AUX
mkg-56898	72	32	the	the	DET
mkg-56898	72	33	therapeutic	therapeutic	ADJ
mkg-56898	72	34	target	target	NOUN
mkg-56898	72	35	for	for	ADP
mkg-56898	72	36	developing	develop	VERB
mkg-56898	72	37	anti	anti	ADJ
mkg-56898	72	38	-	-	ADJ
mkg-56898	72	39	inflammatory	inflammatory	ADJ
mkg-56898	72	40	drugs	drug	NOUN
mkg-56898	72	41	,	,	PUNCT
mkg-56898	72	42	emerging	emerge	VERB
mkg-56898	72	43	evidence	evidence	NOUN
mkg-56898	72	44	suggests	suggest	VERB
mkg-56898	72	45	ptgs1	ptgs1	NOUN
mkg-56898	72	46	also	also	ADV
mkg-56898	72	47	contributes	contribute	VERB
mkg-56898	72	48	to	to	ADP
mkg-56898	72	49	regulating	regulate	VERB
mkg-56898	72	50	inflammation	inflammation	NOUN
mkg-56898	72	51	.	.	PUNCT
mkg-56898	73	1	our	our	PRON
mkg-56898	73	2	study	study	NOUN
mkg-56898	73	3	results	result	NOUN
mkg-56898	73	4	showed	show	VERB
mkg-56898	73	5	diclofenac	diclofenac	ADJ
mkg-56898	73	6	sodium	sodium	NOUN
mkg-56898	73	7	’s	’s	PART
mkg-56898	73	8	potential	potential	ADJ
mkg-56898	73	9	drawbacks	drawback	NOUN
mkg-56898	73	10	due	due	ADJ
mkg-56898	73	11	to	to	ADP
mkg-56898	73	12	its	its	PRON
mkg-56898	73	13	influence	influence	NOUN
mkg-56898	73	14	on	on	ADP
mkg-56898	73	15	genes	gene	NOUN
mkg-56898	73	16	regulating	regulate	VERB
mkg-56898	73	17	hormonal	hormonal	ADJ
mkg-56898	73	18	function	function	NOUN
mkg-56898	73	19	.	.	PUNCT
mkg-56898	74	1	the	the	DET
mkg-56898	74	2	htr2a	htr2a	NOUN
mkg-56898	74	3	,	,	PUNCT
mkg-56898	74	4	esr2	esr2	PROPN
mkg-56898	74	5	,	,	PUNCT
mkg-56898	74	6	and	and	CCONJ
mkg-56898	74	7	drd4	drd4	NOUN
mkg-56898	74	8	genes	gene	NOUN
mkg-56898	74	9	encode	encode	VERB
mkg-56898	74	10	the	the	DET
mkg-56898	74	11	receptors	receptor	NOUN
mkg-56898	74	12	of	of	ADP
mkg-56898	74	13	serotonin	serotonin	NOUN
mkg-56898	74	14	,	,	PUNCT
mkg-56898	74	15	estrogen	estrogen	NOUN
mkg-56898	74	16	,	,	PUNCT
mkg-56898	74	17	and	and	CCONJ
mkg-56898	74	18	dopamine	dopamine	NOUN
mkg-56898	74	19	,	,	PUNCT
mkg-56898	74	20	respectively	respectively	ADV
mkg-56898	74	21	(	(	PUNCT
mkg-56898	74	22	national	national	ADJ
mkg-56898	74	23	library	library	NOUN
mkg-56898	74	24	of	of	ADP
mkg-56898	74	25	medicine	medicine	NOUN
mkg-56898	74	26	–	–	PUNCT
mkg-56898	74	27	nih	nih	PROPN
mkg-56898	74	28	,	,	PUNCT
mkg-56898	74	29	usa	usa	PROPN
mkg-56898	74	30	)	)	PUNCT
mkg-56898	74	31	.	.	PUNCT
mkg-56898	75	1	moreover	moreover	ADV
mkg-56898	75	2	,	,	PUNCT
mkg-56898	75	3	curcumin	curcumin	NOUN
mkg-56898	75	4	also	also	ADV
mkg-56898	75	5	targets	target	VERB
mkg-56898	75	6	drd4	drd4	NOUN
mkg-56898	75	7	genes	gene	NOUN
mkg-56898	75	8	,	,	PUNCT
mkg-56898	75	9	implying	imply	VERB
mkg-56898	75	10	the	the	DET
mkg-56898	75	11	possibility	possibility	NOUN
mkg-56898	75	12	of	of	ADP
mkg-56898	75	13	influencing	influence	VERB
mkg-56898	75	14	neurological	neurological	ADJ
mkg-56898	75	15	function	function	NOUN
mkg-56898	75	16	.	.	PUNCT
mkg-56898	76	1	unlike	unlike	ADP
mkg-56898	76	2	diclofenac	diclofenac	NOUN
mkg-56898	76	3	sodium	sodium	NOUN
mkg-56898	76	4	and	and	CCONJ
mkg-56898	76	5	curcumin	curcumin	NOUN
mkg-56898	76	6	,	,	PUNCT
mkg-56898	76	7	pgv-0	pgv-0	PUNCT
mkg-56898	76	8	is	be	AUX
mkg-56898	76	9	not	not	PART
mkg-56898	76	10	shown	show	VERB
mkg-56898	76	11	to	to	PART
mkg-56898	76	12	be	be	AUX
mkg-56898	76	13	related	relate	VERB
mkg-56898	76	14	to	to	ADP
mkg-56898	76	15	hormone	hormone	NOUN
mkg-56898	76	16	-	-	PUNCT
mkg-56898	76	17	related	relate	VERB
mkg-56898	76	18	genes	gene	NOUN
mkg-56898	76	19	.	.	PUNCT
mkg-56898	77	1	the	the	DET
mkg-56898	77	2	molecular	molecular	ADJ
mkg-56898	77	3	targets	target	NOUN
mkg-56898	77	4	,	,	PUNCT
mkg-56898	77	5	such	such	ADJ
mkg-56898	77	6	as	as	ADP
mkg-56898	77	7	tnf	tnf	PROPN
mkg-56898	77	8	-	-	PUNCT
mkg-56898	77	9	α	α	PROPN
mkg-56898	77	10	,	,	PUNCT
mkg-56898	77	11	blc-2	blc-2	NOUN
mkg-56898	77	12	,	,	PUNCT
mkg-56898	77	13	and	and	CCONJ
mkg-56898	77	14	lyn	lyn	PROPN
mkg-56898	77	15	genes	gene	NOUN
mkg-56898	77	16	,	,	PUNCT
mkg-56898	77	17	are	be	AUX
mkg-56898	77	18	not	not	PART
mkg-56898	77	19	aimed	aim	VERB
mkg-56898	77	20	at	at	ADP
mkg-56898	77	21	diclofenac	diclofenac	ADJ
mkg-56898	77	22	sodium	sodium	NOUN
mkg-56898	77	23	and	and	CCONJ
mkg-56898	77	24	curcumin	curcumin	NOUN
mkg-56898	77	25	.	.	PUNCT
mkg-56898	78	1	these	these	DET
mkg-56898	78	2	genes	gene	NOUN
mkg-56898	78	3	are	be	AUX
mkg-56898	78	4	related	relate	VERB
mkg-56898	78	5	to	to	ADP
mkg-56898	78	6	the	the	DET
mkg-56898	78	7	innate	innate	ADJ
mkg-56898	78	8	and	and	CCONJ
mkg-56898	78	9	adaptive	adaptive	ADJ
mkg-56898	78	10	immune	immune	ADJ
mkg-56898	78	11	response	response	NOUN
mkg-56898	78	12	in	in	ADP
mkg-56898	78	13	terms	term	NOUN
mkg-56898	78	14	of	of	ADP
mkg-56898	78	15	playing	play	VERB
mkg-56898	78	16	roles	role	NOUN
mkg-56898	78	17	in	in	ADP
mkg-56898	78	18	the	the	DET
mkg-56898	78	19	apoptosis	apoptosis	NOUN
mkg-56898	78	20	regulation	regulation	NOUN
mkg-56898	78	21	of	of	ADP
mkg-56898	78	22	lymphocytes	lymphocyte	NOUN
mkg-56898	78	23	(	(	PUNCT
mkg-56898	78	24	blc-2	blc-2	NOUN
mkg-56898	78	25	)	)	PUNCT
mkg-56898	78	26	,	,	PUNCT
mkg-56898	78	27	mast	mast	NOUN
mkg-56898	78	28	cell	cell	NOUN
mkg-56898	78	29	degranulation	degranulation	NOUN
mkg-56898	78	30	(	(	PUNCT
mkg-56898	78	31	lyn	lyn	PROPN
mkg-56898	78	32	)	)	PUNCT
mkg-56898	78	33	,	,	PUNCT
mkg-56898	78	34	and	and	CCONJ
mkg-56898	78	35	pro	pro	ADJ
mkg-56898	78	36	-	-	ADJ
mkg-56898	78	37	inflammatory	inflammatory	ADJ
mkg-56898	78	38	cytokines	cytokine	NOUN
mkg-56898	78	39	(	(	PUNCT
mkg-56898	78	40	tnf	tnf	PROPN
mkg-56898	78	41	-	-	PUNCT
mkg-56898	78	42	α	α	NOUN
mkg-56898	78	43	)	)	PUNCT
mkg-56898	78	44	.	.	PUNCT
mkg-56898	79	1	compared	compare	VERB
mkg-56898	79	2	to	to	ADP
mkg-56898	79	3	pgv-0	pgv-0	NOUN
mkg-56898	79	4	,	,	PUNCT
mkg-56898	79	5	curcumin	curcumin	NOUN
mkg-56898	79	6	dominates	dominate	VERB
mkg-56898	79	7	in	in	ADP
mkg-56898	79	8	molecular	molecular	ADJ
mkg-56898	79	9	targets	target	NOUN
mkg-56898	79	10	involved	involve	VERB
mkg-56898	79	11	in	in	ADP
mkg-56898	79	12	extracellular	extracellular	ADJ
mkg-56898	79	13	degradation	degradation	NOUN
mkg-56898	79	14	.	.	PUNCT
mkg-56898	80	1	this	this	PRON
mkg-56898	80	2	is	be	AUX
mkg-56898	80	3	shown	show	VERB
mkg-56898	80	4	by	by	ADP
mkg-56898	80	5	its	its	PRON
mkg-56898	80	6	interaction	interaction	NOUN
mkg-56898	80	7	with	with	ADP
mkg-56898	80	8	mmp-3	mmp-3	NUM
mkg-56898	80	9	and	and	CCONJ
mkg-56898	80	10	mmp-8	mmp-8	NOUN
mkg-56898	80	11	,	,	PUNCT
mkg-56898	80	12	which	which	PRON
mkg-56898	80	13	are	be	AUX
mkg-56898	80	14	not	not	PART
mkg-56898	80	15	present	present	ADJ
mkg-56898	80	16	as	as	ADP
mkg-56898	80	17	targets	target	NOUN
mkg-56898	80	18	of	of	ADP
mkg-56898	80	19	pgv-0	pgv-0	NOUN
mkg-56898	80	20	.	.	PUNCT
mkg-56898	81	1	on	on	ADP
mkg-56898	81	2	the	the	DET
mkg-56898	81	3	other	other	ADJ
mkg-56898	81	4	hand	hand	NOUN
mkg-56898	81	5	,	,	PUNCT
mkg-56898	81	6	pgv-0	pgv-0	PUNCT
mkg-56898	81	7	also	also	ADV
mkg-56898	81	8	targets	target	VERB
mkg-56898	81	9	tnf	tnf	PROPN
mkg-56898	81	10	genes	gene	NOUN
mkg-56898	81	11	,	,	PUNCT
mkg-56898	81	12	which	which	PRON
mkg-56898	81	13	are	be	AUX
mkg-56898	81	14	important	important	ADJ
mkg-56898	81	15	for	for	ADP
mkg-56898	81	16	proinflammatory	proinflammatory	ADJ
mkg-56898	81	17	cytokine	cytokine	NOUN
mkg-56898	81	18	synthesis	synthesis	NOUN
mkg-56898	81	19	.	.	PUNCT
mkg-56898	82	1	these	these	DET
mkg-56898	82	2	results	result	NOUN
mkg-56898	82	3	indicate	indicate	VERB
mkg-56898	82	4	that	that	SCONJ
mkg-56898	82	5	the	the	DET
mkg-56898	82	6	slight	slight	ADJ
mkg-56898	82	7	difference	difference	NOUN
mkg-56898	82	8	in	in	ADP
mkg-56898	82	9	the	the	DET
mkg-56898	82	10	molecular	molecular	ADJ
mkg-56898	82	11	structure	structure	NOUN
mkg-56898	82	12	of	of	ADP
mkg-56898	82	13	pgv-0	pgv-0	PUNCT
mkg-56898	82	14	to	to	PART
mkg-56898	82	15	curcumin	curcumin	NOUN
mkg-56898	82	16	leads	lead	NOUN
mkg-56898	82	17	to	to	ADP
mkg-56898	82	18	the	the	DET
mkg-56898	82	19	possibility	possibility	NOUN
mkg-56898	82	20	of	of	ADP
mkg-56898	82	21	distinct	distinct	ADJ
mkg-56898	82	22	targets	target	NOUN
mkg-56898	82	23	of	of	ADP
mkg-56898	82	24	pgv-0	pgv-0	PUNCT
mkg-56898	82	25	for	for	ADP
mkg-56898	82	26	temporomandibular	temporomandibular	ADJ
mkg-56898	82	27	arthritis	arthritis	NOUN
mkg-56898	82	28	.	.	PUNCT
mkg-56898	83	1	we	we	PRON
mkg-56898	83	2	curated	curate	VERB
mkg-56898	83	3	temporomandibular	temporomandibular	ADJ
mkg-56898	83	4	arthritis	arthritis	NOUN
mkg-56898	83	5	to	to	PART
mkg-56898	83	6	determine	determine	VERB
mkg-56898	83	7	each	each	DET
mkg-56898	83	8	gene	gene	NOUN
mkg-56898	83	9	’s	’s	PART
mkg-56898	83	10	interaction	interaction	NOUN
mkg-56898	83	11	with	with	ADP
mkg-56898	83	12	diclofenac	diclofenac	ADJ
mkg-56898	83	13	sodium	sodium	NOUN
mkg-56898	83	14	,	,	PUNCT
mkg-56898	83	15	curcumin	curcumin	NOUN
mkg-56898	83	16	,	,	PUNCT
mkg-56898	83	17	and	and	CCONJ
mkg-56898	83	18	pgv-0	pgv-0	PUNCT
mkg-56898	83	19	and	and	CCONJ
mkg-56898	83	20	then	then	ADV
mkg-56898	83	21	visualized	visualize	VERB
mkg-56898	83	22	the	the	DET
mkg-56898	83	23	network	network	NOUN
mkg-56898	83	24	through	through	ADP
mkg-56898	83	25	string	string	NOUN
mkg-56898	83	26	web	web	NOUN
mkg-56898	83	27	tools	tool	NOUN
mkg-56898	83	28	.	.	PUNCT
mkg-56898	84	1	protein	protein	NOUN
mkg-56898	84	2	–	–	PUNCT
mkg-56898	84	3	protein	protein	NOUN
mkg-56898	84	4	interactions	interaction	NOUN
mkg-56898	84	5	between	between	ADP
mkg-56898	84	6	diclofenac	diclofenac	ADJ
mkg-56898	84	7	sodium	sodium	NOUN
mkg-56898	84	8	,	,	PUNCT
mkg-56898	84	9	curcumin	curcumin	NOUN
mkg-56898	84	10	,	,	PUNCT
mkg-56898	84	11	pgv-0	pgv-0	NOUN
mkg-56898	84	12	,	,	PUNCT
mkg-56898	84	13	and	and	CCONJ
mkg-56898	84	14	inflammatory	inflammatory	ADJ
mkg-56898	84	15	targets	target	NOUN
mkg-56898	84	16	were	be	AUX
mkg-56898	84	17	predicted	predict	VERB
mkg-56898	84	18	using	use	VERB
mkg-56898	84	19	string	string	NOUN
mkg-56898	84	20	v11.0	v11.0	PROPN
mkg-56898	84	21	.	.	PROPN
mkg-56898	84	22	string	string	NOUN
mkg-56898	84	23	analyzes	analyze	NOUN
mkg-56898	84	24	known	know	VERB
mkg-56898	84	25	and	and	CCONJ
mkg-56898	84	26	predicted	predict	VERB
mkg-56898	84	27	protein	protein	NOUN
mkg-56898	84	28	–	–	PUNCT
mkg-56898	84	29	protein	protein	NOUN
mkg-56898	84	30	associations	association	NOUN
mkg-56898	84	31	with	with	ADP
mkg-56898	84	32	direct	direct	ADJ
mkg-56898	84	33	(	(	PUNCT
mkg-56898	84	34	physical	physical	ADJ
mkg-56898	84	35	)	)	PUNCT
mkg-56898	84	36	and	and	CCONJ
mkg-56898	84	37	indirect	indirect	ADJ
mkg-56898	84	38	(	(	PUNCT
mkg-56898	84	39	functional	functional	ADJ
mkg-56898	84	40	)	)	PUNCT
mkg-56898	84	41	evidence	evidence	NOUN
mkg-56898	84	42	.	.	PUNCT
mkg-56898	85	1	we	we	PRON
mkg-56898	85	2	searched	search	VERB
mkg-56898	85	3	for	for	ADP
mkg-56898	85	4	interactions	interaction	NOUN
mkg-56898	85	5	between	between	ADP
mkg-56898	85	6	each	each	DET
mkg-56898	85	7	gene	gene	NOUN
mkg-56898	85	8	associated	associate	VERB
mkg-56898	85	9	with	with	ADP
mkg-56898	85	10	diclofenac	diclofenac	ADJ
mkg-56898	85	11	sodium	sodium	NOUN
mkg-56898	85	12	(	(	PUNCT
mkg-56898	85	13	drugbank	drugbank	NOUN
mkg-56898	85	14	i	i	PROPN
mkg-56898	85	15	d	d	PROPN
mkg-56898	85	16	:	:	PUNCT
mkg-56898	85	17	db01097	db01097	PROPN
mkg-56898	85	18	)	)	PUNCT
mkg-56898	85	19	,	,	PUNCT
mkg-56898	85	20	curcumin	curcumin	NOUN
mkg-56898	85	21	(	(	PUNCT
mkg-56898	85	22	pubchem	pubchem	NOUN
mkg-56898	85	23	cid	cid	NOUN
mkg-56898	85	24	:	:	PUNCT
mkg-56898	85	25	969516	969516	NUM
mkg-56898	85	26	)	)	PUNCT
mkg-56898	85	27	,	,	PUNCT
mkg-56898	85	28	or	or	CCONJ
mkg-56898	85	29	pgv-0	pgv-0	PUNCT
mkg-56898	85	30	(	(	PUNCT
mkg-56898	85	31	no	no	DET
mkg-56898	85	32	identifier	identifier	NOUN
mkg-56898	85	33	,	,	PUNCT
mkg-56898	85	34	structure	structure	NOUN
mkg-56898	85	35	formula	formula	NOUN
mkg-56898	85	36	provided	provide	VERB
mkg-56898	85	37	)	)	PUNCT
mkg-56898	85	38	,	,	PUNCT
mkg-56898	85	39	and	and	CCONJ
mkg-56898	85	40	inflammatory	inflammatory	ADJ
mkg-56898	85	41	targets	target	NOUN
mkg-56898	85	42	mmp-3	mmp-3	NUM
mkg-56898	85	43	(	(	PUNCT
mkg-56898	85	44	p08254	p08254	PROPN
mkg-56898	85	45	)	)	PUNCT
mkg-56898	85	46	,	,	PUNCT
mkg-56898	85	47	mmp-13	mmp-13	PROPN
mkg-56898	85	48	(	(	PUNCT
mkg-56898	85	49	p45452	p45452	NOUN
mkg-56898	85	50	)	)	PUNCT
mkg-56898	85	51	,	,	PUNCT
mkg-56898	85	52	il-1β	il-1β	PROPN
mkg-56898	85	53	(	(	PUNCT
mkg-56898	85	54	p01584	p01584	PROPN
mkg-56898	85	55	)	)	PUNCT
mkg-56898	85	56	,	,	PUNCT
mkg-56898	86	1	tnf	tnf	PROPN
mkg-56898	86	2	-	-	PUNCT
mkg-56898	86	3	α	α	PROPN
mkg-56898	86	4	(	(	PUNCT
mkg-56898	86	5	p01375	p01375	PROPN
mkg-56898	86	6	)	)	PUNCT
mkg-56898	86	7	,	,	PUNCT
mkg-56898	86	8	and	and	CCONJ
mkg-56898	86	9	nf	nf	X
mkg-56898	86	10	-	-	PUNCT
mkg-56898	86	11	kb	kb	NOUN
mkg-56898	86	12	(	(	PUNCT
mkg-56898	86	13	p19838	p19838	PROPN
mkg-56898	86	14	)	)	PUNCT
mkg-56898	86	15	.	.	PUNCT
mkg-56898	87	1	we	we	PRON
mkg-56898	87	2	outlined	outline	VERB
mkg-56898	87	3	three	three	NUM
mkg-56898	87	4	types	type	NOUN
mkg-56898	87	5	of	of	ADP
mkg-56898	87	6	gene	gene	NOUN
mkg-56898	87	7	interaction	interaction	NOUN
mkg-56898	87	8	in	in	ADP
mkg-56898	87	9	diclofenac	diclofenac	ADJ
mkg-56898	87	10	sodium	sodium	NOUN
mkg-56898	87	11	,	,	PUNCT
mkg-56898	87	12	curcumin	curcumin	NOUN
mkg-56898	87	13	,	,	PUNCT
mkg-56898	87	14	and	and	CCONJ
mkg-56898	87	15	pgv-0	pgv-0	NOUN
mkg-56898	87	16	,	,	PUNCT
mkg-56898	87	17	including	include	VERB
mkg-56898	87	18	co	co	NOUN
mkg-56898	87	19	-	-	NOUN
mkg-56898	87	20	expression	expression	NOUN
mkg-56898	87	21	,	,	PUNCT
mkg-56898	87	22	co	co	NOUN
mkg-56898	87	23	-	-	NOUN
mkg-56898	87	24	occurrence	occurrence	NOUN
mkg-56898	87	25	,	,	PUNCT
mkg-56898	87	26	and	and	CCONJ
mkg-56898	87	27	insignificant	insignificant	ADJ
mkg-56898	87	28	association	association	NOUN
mkg-56898	87	29	.	.	PUNCT
mkg-56898	88	1	co	co	NOUN
mkg-56898	88	2	-	-	NOUN
mkg-56898	88	3	expression	expression	NOUN
mkg-56898	88	4	indicates	indicate	VERB
mkg-56898	88	5	that	that	SCONJ
mkg-56898	88	6	two	two	NUM
mkg-56898	88	7	proteins	protein	NOUN
mkg-56898	88	8	show	show	VERB
mkg-56898	88	9	similar	similar	ADJ
mkg-56898	88	10	expression	expression	NOUN
mkg-56898	88	11	patterns	pattern	NOUN
mkg-56898	88	12	across	across	ADP
mkg-56898	88	13	conditions	condition	NOUN
mkg-56898	88	14	;	;	PUNCT
mkg-56898	88	15	they	they	PRON
mkg-56898	88	16	are	be	AUX
mkg-56898	88	17	often	often	ADV
mkg-56898	88	18	involved	involve	VERB
mkg-56898	88	19	in	in	ADP
mkg-56898	88	20	similar	similar	ADJ
mkg-56898	88	21	biological	biological	ADJ
mkg-56898	88	22	processes	process	NOUN
mkg-56898	88	23	and	and	CCONJ
mkg-56898	88	24	pathways	pathway	NOUN
mkg-56898	88	25	.	.	PUNCT
mkg-56898	89	1	co	co	NOUN
mkg-56898	89	2	-	-	NOUN
mkg-56898	89	3	occurrence	occurrence	NOUN
mkg-56898	89	4	means	mean	VERB
mkg-56898	89	5	two	two	NUM
mkg-56898	89	6	proteins	protein	NOUN
mkg-56898	89	7	are	be	AUX
mkg-56898	89	8	often	often	ADV
mkg-56898	89	9	mentioned	mention	VERB
mkg-56898	89	10	together	together	ADV
mkg-56898	89	11	in	in	ADP
mkg-56898	89	12	scientific	scientific	ADJ
mkg-56898	89	13	literature	literature	NOUN
mkg-56898	89	14	;	;	PUNCT
mkg-56898	89	15	they	they	PRON
mkg-56898	89	16	are	be	AUX
mkg-56898	89	17	often	often	ADV
mkg-56898	89	18	studied	study	VERB
mkg-56898	89	19	together	together	ADV
mkg-56898	89	20	and	and	CCONJ
mkg-56898	89	21	may	may	AUX
mkg-56898	89	22	interact	interact	VERB
mkg-56898	89	23	or	or	CCONJ
mkg-56898	89	24	be	be	AUX
mkg-56898	89	25	part	part	NOUN
mkg-56898	89	26	of	of	ADP
mkg-56898	89	27	the	the	DET
mkg-56898	89	28	same	same	ADJ
mkg-56898	89	29	biological	biological	ADJ
mkg-56898	89	30	processes	process	NOUN
mkg-56898	89	31	and	and	CCONJ
mkg-56898	89	32	pathways	pathway	NOUN
mkg-56898	89	33	.	.	PUNCT
mkg-56898	90	1	insignificant	insignificant	ADJ
mkg-56898	90	2	means	mean	VERB
mkg-56898	90	3	there	there	PRON
mkg-56898	90	4	is	be	VERB
mkg-56898	90	5	no	no	DET
mkg-56898	90	6	significant	significant	ADJ
mkg-56898	90	7	evidence	evidence	NOUN
mkg-56898	90	8	that	that	SCONJ
mkg-56898	90	9	the	the	DET
mkg-56898	90	10	two	two	NUM
mkg-56898	90	11	proteins	protein	NOUN
mkg-56898	90	12	interact	interact	VERB
mkg-56898	90	13	or	or	CCONJ
mkg-56898	90	14	are	be	AUX
mkg-56898	90	15	functionally	functionally	ADV
mkg-56898	90	16	associated	associate	VERB
mkg-56898	90	17	based	base	VERB
mkg-56898	90	18	on	on	ADP
mkg-56898	90	19	the	the	DET
mkg-56898	90	20	data	datum	NOUN
mkg-56898	90	21	sources	source	NOUN
mkg-56898	90	22	in	in	ADP
mkg-56898	90	23	string	string	NOUN
mkg-56898	90	24	.	.	PUNCT
mkg-56898	91	1	the	the	DET
mkg-56898	91	2	interaction	interaction	NOUN
mkg-56898	91	3	network	network	NOUN
mkg-56898	91	4	model	model	NOUN
mkg-56898	91	5	(	(	PUNCT
mkg-56898	91	6	figure	figure	NOUN
mkg-56898	91	7	2	2	NUM
mkg-56898	91	8	)	)	PUNCT
mkg-56898	91	9	indicated	indicate	VERB
mkg-56898	91	10	that	that	SCONJ
mkg-56898	91	11	diclofenac	diclofenac	NOUN
mkg-56898	91	12	sodium	sodium	NOUN
mkg-56898	91	13	targeted	target	VERB
mkg-56898	91	14	inflammatory	inflammatory	ADJ
mkg-56898	91	15	-	-	PUNCT
mkg-56898	91	16	related	relate	VERB
mkg-56898	91	17	protein	protein	NOUN
mkg-56898	91	18	synthesis	synthesis	NOUN
mkg-56898	91	19	.	.	PUNCT
mkg-56898	92	1	meanwhile	meanwhile	ADV
mkg-56898	92	2	,	,	PUNCT
mkg-56898	92	3	curcumin	curcumin	NOUN
mkg-56898	92	4	and	and	CCONJ
mkg-56898	92	5	pgv-0	pgv-0	PUNCT
mkg-56898	92	6	gene	gene	NOUN
mkg-56898	92	7	interactions	interaction	NOUN
mkg-56898	92	8	were	be	AUX
mkg-56898	92	9	more	more	ADV
mkg-56898	92	10	related	related	ADJ
mkg-56898	92	11	to	to	ADP
mkg-56898	92	12	the	the	DET
mkg-56898	92	13	matrix	matrix	NOUN
mkg-56898	92	14	extracellular	extracellular	ADJ
mkg-56898	92	15	degradation	degradation	NOUN
mkg-56898	92	16	via	via	ADP
mkg-56898	92	17	mmp	mmp	PROPN
mkg-56898	92	18	regulation	regulation	PROPN
mkg-56898	92	19	.	.	PUNCT
mkg-56898	93	1	mmps	mmp	NOUN
mkg-56898	93	2	are	be	AUX
mkg-56898	93	3	involved	involve	VERB
mkg-56898	93	4	figure	figure	NOUN
mkg-56898	93	5	1	1	NUM
mkg-56898	93	6	.	.	PUNCT
mkg-56898	94	1	the	the	DET
mkg-56898	94	2	estimated	estimate	VERB
mkg-56898	94	3	number	number	NOUN
mkg-56898	94	4	of	of	ADP
mkg-56898	94	5	target	target	NOUN
mkg-56898	94	6	genes	gene	NOUN
mkg-56898	94	7	of	of	ADP
mkg-56898	94	8	(	(	PUNCT
mkg-56898	94	9	a	a	X
mkg-56898	94	10	)	)	PUNCT
mkg-56898	94	11	diclofenac	diclofenac	NOUN
mkg-56898	94	12	sodium	sodium	NOUN
mkg-56898	94	13	,	,	PUNCT
mkg-56898	94	14	(	(	PUNCT
mkg-56898	94	15	b	b	X
mkg-56898	94	16	)	)	PUNCT
mkg-56898	94	17	curcumin	curcumin	NOUN
mkg-56898	94	18	,	,	PUNCT
mkg-56898	94	19	and	and	CCONJ
mkg-56898	94	20	(	(	PUNCT
mkg-56898	94	21	c	c	NOUN
mkg-56898	94	22	)	)	PUNCT
mkg-56898	94	23	pentagamavunon-0	pentagamavunon-0	X
mkg-56898	94	24	(	(	PUNCT
mkg-56898	94	25	pgv-0	pgv-0	NOUN
mkg-56898	94	26	)	)	PUNCT
mkg-56898	94	27	based	base	VERB
mkg-56898	94	28	on	on	ADP
mkg-56898	94	29	the	the	DET
mkg-56898	94	30	intersection	intersection	NOUN
mkg-56898	94	31	between	between	ADP
mkg-56898	94	32	associated	associated	ADJ
mkg-56898	94	33	genes	gene	NOUN
mkg-56898	94	34	in	in	ADP
mkg-56898	94	35	temporomandibular	temporomandibular	ADJ
mkg-56898	94	36	(	(	PUNCT
mkg-56898	94	37	tm	tm	NOUN
mkg-56898	94	38	)	)	PUNCT
mkg-56898	94	39	arthritis	arthritis	NOUN
mkg-56898	94	40	collected	collect	VERB
mkg-56898	94	41	from	from	ADP
mkg-56898	94	42	genecards	genecard	NOUN
mkg-56898	94	43	and	and	CCONJ
mkg-56898	94	44	prediction	prediction	NOUN
mkg-56898	94	45	targets	target	NOUN
mkg-56898	94	46	of	of	ADP
mkg-56898	94	47	each	each	DET
mkg-56898	94	48	compound	compound	NOUN
mkg-56898	94	49	from	from	ADP
mkg-56898	94	50	swisstargetprediction	swisstargetprediction	NOUN
mkg-56898	94	51	.	.	PUNCT
mkg-56898	95	1	copyright	copyright	NOUN
mkg-56898	95	2	©	©	PROPN
mkg-56898	95	3	2025	2025	NUM
mkg-56898	95	4	dental	dental	ADJ
mkg-56898	95	5	journal	journal	NOUN
mkg-56898	95	6	(	(	PUNCT
mkg-56898	95	7	majalah	majalah	PROPN
mkg-56898	95	8	kedokteran	kedokteran	PROPN
mkg-56898	95	9	gigi	gigi	PROPN
mkg-56898	95	10	)	)	PUNCT
mkg-56898	96	1	p	p	X
mkg-56898	96	2	-	-	PUNCT
mkg-56898	96	3	issn	issn	NOUN
mkg-56898	96	4	:	:	PUNCT
mkg-56898	96	5	1978	1978	NUM
mkg-56898	96	6	-	-	SYM
mkg-56898	96	7	3728	3728	NUM
mkg-56898	96	8	;	;	PUNCT
mkg-56898	96	9	e	e	X
mkg-56898	96	10	-	-	PUNCT
mkg-56898	96	11	issn	issn	ADJ
mkg-56898	96	12	:	:	PUNCT
mkg-56898	96	13	2442	2442	NUM
mkg-56898	96	14	-	-	SYM
mkg-56898	96	15	9740	9740	NUM
mkg-56898	96	16	.	.	PUNCT
mkg-56898	97	1	accredited	accredit	VERB
mkg-56898	97	2	no	no	INTJ
mkg-56898	97	3	.	.	PROPN
mkg-56898	98	1	158	158	NUM
mkg-56898	98	2	/	/	SYM
mkg-56898	98	3	e	e	NOUN
mkg-56898	98	4	/	/	SYM
mkg-56898	98	5	kpt/2021	kpt/2021	NOUN
mkg-56898	98	6	.	.	PUNCT
mkg-56898	99	1	open	open	ADJ
mkg-56898	99	2	access	access	NOUN
mkg-56898	99	3	under	under	ADP
mkg-56898	99	4	cc	cc	NOUN
mkg-56898	99	5	-	-	PUNCT
mkg-56898	99	6	by	by	ADP
mkg-56898	99	7	-	-	PUNCT
mkg-56898	99	8	sa	sa	NOUN
mkg-56898	99	9	license	license	NOUN
mkg-56898	99	10	.	.	PUNCT
mkg-56898	100	1	available	available	ADJ
mkg-56898	100	2	at	at	ADP
mkg-56898	100	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	100	4	doi	doi	NOUN
mkg-56898	100	5	:	:	PUNCT
mkg-56898	100	6	10.20473	10.20473	NUM
mkg-56898	100	7	/	/	SYM
mkg-56898	100	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	PROPN
mkg-56898	100	9	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	100	10	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	101	1	370	370	NUM
mkg-56898	101	2	robin	robin	PROPN
mkg-56898	101	3	et	et	PROPN
mkg-56898	101	4	al	al	PROPN
mkg-56898	101	5	.	.	PROPN
mkg-56898	101	6	dent	dent	PROPN
mkg-56898	101	7	.	.	PUNCT
mkg-56898	102	1	j.	j.	PROPN
mkg-56898	102	2	(	(	PUNCT
mkg-56898	102	3	majalah	majalah	PROPN
mkg-56898	102	4	kedokteran	kedokteran	PROPN
mkg-56898	102	5	gigi	gigi	PROPN
mkg-56898	102	6	)	)	PUNCT
mkg-56898	102	7	2025	2025	NUM
mkg-56898	102	8	december	december	NOUN
mkg-56898	102	9	;	;	PUNCT
mkg-56898	102	10	58(4	58(4	NUM
mkg-56898	102	11	):	):	PUNCT
mkg-56898	102	12	367–375	367–375	NUM
mkg-56898	102	13	in	in	ADP
mkg-56898	102	14	extracellular	extracellular	ADJ
mkg-56898	102	15	matrix	matrix	NOUN
mkg-56898	102	16	degradation	degradation	NOUN
mkg-56898	102	17	,	,	PUNCT
mkg-56898	102	18	leading	lead	VERB
mkg-56898	102	19	to	to	ADP
mkg-56898	102	20	cartilage	cartilage	NOUN
mkg-56898	102	21	destruction	destruction	NOUN
mkg-56898	102	22	in	in	ADP
mkg-56898	102	23	arthritis	arthritis	NOUN
mkg-56898	102	24	,	,	PUNCT
mkg-56898	102	25	including	include	VERB
mkg-56898	102	26	temporomandibular	temporomandibular	ADJ
mkg-56898	102	27	arthritis	arthritis	NOUN
mkg-56898	102	28	.	.	PUNCT
mkg-56898	103	1	specifically	specifically	ADV
mkg-56898	103	2	,	,	PUNCT
mkg-56898	103	3	mmp-9	mmp-9	NOUN
mkg-56898	103	4	and	and	CCONJ
mkg-56898	103	5	mmp-13	mmp-13	AUX
mkg-56898	103	6	mediate	mediate	VERB
mkg-56898	103	7	pathological	pathological	ADJ
mkg-56898	103	8	processes	process	NOUN
mkg-56898	103	9	resulting	result	VERB
mkg-56898	103	10	in	in	ADP
mkg-56898	103	11	the	the	DET
mkg-56898	103	12	degradation	degradation	NOUN
mkg-56898	103	13	of	of	ADP
mkg-56898	103	14	collagen	collagen	NOUN
mkg-56898	103	15	and	and	CCONJ
mkg-56898	103	16	the	the	DET
mkg-56898	103	17	onset	onset	NOUN
mkg-56898	103	18	of	of	ADP
mkg-56898	103	19	inflammatory	inflammatory	ADJ
mkg-56898	103	20	symptoms	symptom	NOUN
mkg-56898	103	21	in	in	ADP
mkg-56898	103	22	temporomandibular	temporomandibular	ADJ
mkg-56898	103	23	arthritis	arthritis	NOUN
mkg-56898	103	24	patients.21–23	patients.21–23	ADP
mkg-56898	103	25	the	the	DET
mkg-56898	103	26	results	result	NOUN
mkg-56898	103	27	of	of	ADP
mkg-56898	103	28	the	the	DET
mkg-56898	103	29	go	go	NOUN
mkg-56898	103	30	panther	panther	NOUN
mkg-56898	103	31	analysis	analysis	NOUN
mkg-56898	103	32	also	also	ADV
mkg-56898	103	33	support	support	VERB
mkg-56898	103	34	this	this	DET
mkg-56898	103	35	hypothesis	hypothesis	NOUN
mkg-56898	103	36	.	.	PUNCT
mkg-56898	104	1	according	accord	VERB
mkg-56898	104	2	to	to	ADP
mkg-56898	104	3	this	this	DET
mkg-56898	104	4	analysis	analysis	NOUN
mkg-56898	104	5	,	,	PUNCT
mkg-56898	104	6	the	the	DET
mkg-56898	104	7	genes	gene	NOUN
mkg-56898	104	8	associated	associate	VERB
mkg-56898	104	9	with	with	ADP
mkg-56898	104	10	diclofenac	diclofenac	ADJ
mkg-56898	104	11	sodium	sodium	NOUN
mkg-56898	104	12	,	,	PUNCT
mkg-56898	104	13	curcumin	curcumin	NOUN
mkg-56898	104	14	,	,	PUNCT
mkg-56898	104	15	or	or	CCONJ
mkg-56898	104	16	pgv-0	pgv-0	PUNCT
mkg-56898	104	17	that	that	PRON
mkg-56898	104	18	overlap	overlap	NOUN
mkg-56898	104	19	with	with	ADP
mkg-56898	104	20	temporomandibular	temporomandibular	ADJ
mkg-56898	104	21	arthritis	arthritis	NOUN
mkg-56898	104	22	contributed	contribute	VERB
mkg-56898	104	23	to	to	ADP
mkg-56898	104	24	several	several	ADJ
mkg-56898	104	25	molecular	molecular	ADJ
mkg-56898	104	26	functions	function	NOUN
mkg-56898	104	27	,	,	PUNCT
mkg-56898	104	28	biological	biological	ADJ
mkg-56898	104	29	processes	process	NOUN
mkg-56898	104	30	,	,	PUNCT
mkg-56898	104	31	and	and	CCONJ
mkg-56898	104	32	cellular	cellular	ADJ
mkg-56898	104	33	components	component	NOUN
mkg-56898	104	34	(	(	PUNCT
mkg-56898	104	35	figure	figure	NOUN
mkg-56898	104	36	3	3	NUM
mkg-56898	104	37	)	)	PUNCT
mkg-56898	104	38	.	.	PUNCT
mkg-56898	105	1	the	the	DET
mkg-56898	105	2	go	go	VERB
mkg-56898	105	3	panther	panther	NOUN
mkg-56898	105	4	study	study	NOUN
mkg-56898	105	5	showed	show	VERB
mkg-56898	105	6	that	that	SCONJ
mkg-56898	105	7	in	in	ADP
mkg-56898	105	8	the	the	DET
mkg-56898	105	9	molecular	molecular	ADJ
mkg-56898	105	10	function	function	NOUN
mkg-56898	105	11	category	category	NOUN
mkg-56898	105	12	,	,	PUNCT
mkg-56898	105	13	diclofenac	diclofenac	NOUN
mkg-56898	105	14	sodium	sodium	NOUN
mkg-56898	105	15	,	,	PUNCT
mkg-56898	105	16	curcumin	curcumin	NOUN
mkg-56898	105	17	,	,	PUNCT
mkg-56898	105	18	and	and	CCONJ
mkg-56898	105	19	pgv-0	pgv-0	PUNCT
mkg-56898	105	20	correlated	correlate	VERB
mkg-56898	105	21	with	with	ADP
mkg-56898	105	22	10	10	NUM
mkg-56898	105	23	molecular	molecular	ADJ
mkg-56898	105	24	functions	function	NOUN
mkg-56898	105	25	.	.	PUNCT
mkg-56898	106	1	the	the	DET
mkg-56898	106	2	intermolecular	intermolecular	ADJ
mkg-56898	106	3	binding	bind	VERB
mkg-56898	106	4	activity	activity	NOUN
mkg-56898	106	5	in	in	ADP
mkg-56898	106	6	diclofenac	diclofenac	ADJ
mkg-56898	106	7	sodium	sodium	NOUN
mkg-56898	106	8	showed	show	VERB
mkg-56898	106	9	the	the	DET
mkg-56898	106	10	highest	high	ADJ
mkg-56898	106	11	percentage	percentage	NOUN
mkg-56898	106	12	,	,	PUNCT
mkg-56898	106	13	followed	follow	VERB
mkg-56898	106	14	by	by	ADP
mkg-56898	106	15	catalytic	catalytic	ADJ
mkg-56898	106	16	activity	activity	NOUN
mkg-56898	106	17	and	and	CCONJ
mkg-56898	106	18	molecular	molecular	ADJ
mkg-56898	106	19	transducer	transducer	NOUN
mkg-56898	106	20	activity	activity	NOUN
mkg-56898	106	21	.	.	PUNCT
mkg-56898	107	1	curcumin	curcumin	NOUN
mkg-56898	107	2	and	and	CCONJ
mkg-56898	107	3	pgv-0	pgv-0	PUNCT
mkg-56898	107	4	are	be	AUX
mkg-56898	107	5	dominated	dominate	VERB
mkg-56898	107	6	by	by	ADP
mkg-56898	107	7	cytoskeletal	cytoskeletal	ADJ
mkg-56898	107	8	motor	motor	NOUN
mkg-56898	107	9	activity	activity	NOUN
mkg-56898	107	10	,	,	PUNCT
mkg-56898	107	11	continued	continue	VERB
mkg-56898	107	12	by	by	ADP
mkg-56898	107	13	catalytic	catalytic	ADJ
mkg-56898	107	14	and	and	CCONJ
mkg-56898	107	15	molecular	molecular	ADJ
mkg-56898	107	16	transducer	transducer	NOUN
mkg-56898	107	17	activities	activity	NOUN
mkg-56898	107	18	.	.	PUNCT
mkg-56898	108	1	in	in	ADP
mkg-56898	108	2	biological	biological	ADJ
mkg-56898	108	3	process	process	NOUN
mkg-56898	108	4	categories	category	NOUN
mkg-56898	108	5	,	,	PUNCT
mkg-56898	108	6	diclofenac	diclofenac	ADJ
mkg-56898	108	7	sodium	sodium	NOUN
mkg-56898	108	8	predominates	predominate	VERB
mkg-56898	108	9	cellular	cellular	ADJ
mkg-56898	108	10	processes	process	NOUN
mkg-56898	108	11	,	,	PUNCT
mkg-56898	108	12	biological	biological	ADJ
mkg-56898	108	13	function	function	NOUN
mkg-56898	108	14	,	,	PUNCT
mkg-56898	108	15	and	and	CCONJ
mkg-56898	108	16	stimulus	stimulus	ADJ
mkg-56898	108	17	response	response	NOUN
mkg-56898	108	18	.	.	PUNCT
mkg-56898	109	1	curcumin	curcumin	NOUN
mkg-56898	109	2	and	and	CCONJ
mkg-56898	109	3	pgv-0	pgv-0	PUNCT
mkg-56898	109	4	play	play	VERB
mkg-56898	109	5	a	a	DET
mkg-56898	109	6	more	more	ADV
mkg-56898	109	7	significant	significant	ADJ
mkg-56898	109	8	role	role	NOUN
mkg-56898	109	9	in	in	ADP
mkg-56898	109	10	immune	immune	NOUN
mkg-56898	109	11	,	,	PUNCT
mkg-56898	109	12	cellular	cellular	ADJ
mkg-56898	109	13	,	,	PUNCT
mkg-56898	109	14	and	and	CCONJ
mkg-56898	109	15	localization	localization	NOUN
mkg-56898	109	16	processes	process	NOUN
mkg-56898	109	17	.	.	PUNCT
mkg-56898	110	1	based	base	VERB
mkg-56898	110	2	on	on	ADP
mkg-56898	110	3	the	the	DET
mkg-56898	110	4	cellular	cellular	ADJ
mkg-56898	110	5	component	component	NOUN
mkg-56898	110	6	category	category	NOUN
mkg-56898	110	7	,	,	PUNCT
mkg-56898	110	8	all	all	DET
mkg-56898	110	9	three	three	NUM
mkg-56898	110	10	substances	substance	NOUN
mkg-56898	110	11	work	work	VERB
mkg-56898	110	12	to	to	PART
mkg-56898	110	13	dominate	dominate	VERB
mkg-56898	110	14	cellular	cellular	ADJ
mkg-56898	110	15	anatomical	anatomical	ADJ
mkg-56898	110	16	entities	entity	NOUN
mkg-56898	110	17	.	.	PUNCT
mkg-56898	111	1	curcumin	curcumin	NOUN
mkg-56898	111	2	and	and	CCONJ
mkg-56898	111	3	pgv-0	pgv-0	PUNCT
mkg-56898	111	4	influence	influence	NOUN
mkg-56898	111	5	identical	identical	ADJ
mkg-56898	111	6	pathways	pathway	NOUN
mkg-56898	111	7	in	in	ADP
mkg-56898	111	8	temporomandibular	temporomandibular	ADJ
mkg-56898	111	9	arthritis	arthritis	NOUN
mkg-56898	111	10	(	(	PUNCT
mkg-56898	111	11	figure	figure	NOUN
mkg-56898	111	12	4	4	NUM
mkg-56898	111	13	)	)	PUNCT
mkg-56898	111	14	.	.	PUNCT
mkg-56898	112	1	both	both	DET
mkg-56898	112	2	substances	substance	NOUN
mkg-56898	112	3	were	be	AUX
mkg-56898	112	4	found	find	VERB
mkg-56898	112	5	to	to	PART
mkg-56898	112	6	have	have	VERB
mkg-56898	112	7	the	the	DET
mkg-56898	112	8	highest	high	ADJ
mkg-56898	112	9	activity	activity	NOUN
mkg-56898	112	10	in	in	ADP
mkg-56898	112	11	the	the	DET
mkg-56898	112	12	neuroinflammatory	neuroinflammatory	ADJ
mkg-56898	112	13	response	response	NOUN
mkg-56898	112	14	.	.	PUNCT
mkg-56898	113	1	curcumin	curcumin	NOUN
mkg-56898	113	2	alleviates	alleviate	VERB
mkg-56898	113	3	neuroinflammation	neuroinflammation	NOUN
mkg-56898	113	4	by	by	ADP
mkg-56898	113	5	suppressing	suppress	VERB
mkg-56898	113	6	tnf	tnf	PROPN
mkg-56898	113	7	-	-	PUNCT
mkg-56898	113	8	α	α	PROPN
mkg-56898	113	9	,	,	PUNCT
mkg-56898	113	10	il-1β	il-1β	PROPN
mkg-56898	113	11	,	,	PUNCT
mkg-56898	113	12	nitric	nitric	ADJ
mkg-56898	113	13	oxide	oxide	NOUN
mkg-56898	113	14	,	,	PUNCT
mkg-56898	113	15	and	and	CCONJ
mkg-56898	113	16	nf	nf	ADJ
mkg-56898	113	17	-	-	PUNCT
mkg-56898	113	18	κb	κb	NOUN
mkg-56898	113	19	gene	gene	NOUN
mkg-56898	113	20	expression.24	expression.24	NOUN
mkg-56898	113	21	however	however	ADV
mkg-56898	113	22	,	,	PUNCT
mkg-56898	113	23	more	more	ADJ
mkg-56898	113	24	evidence	evidence	NOUN
mkg-56898	113	25	is	be	AUX
mkg-56898	113	26	needed	need	VERB
mkg-56898	113	27	to	to	PART
mkg-56898	113	28	highlight	highlight	VERB
mkg-56898	113	29	pgv-0	pgv-0	ADJ
mkg-56898	113	30	action	action	NOUN
mkg-56898	113	31	against	against	ADP
mkg-56898	113	32	neuroinflammation	neuroinflammation	NOUN
mkg-56898	113	33	.	.	PUNCT
mkg-56898	114	1	unlike	unlike	ADP
mkg-56898	114	2	diclofenac	diclofenac	NOUN
mkg-56898	114	3	sodium	sodium	NOUN
mkg-56898	114	4	,	,	PUNCT
mkg-56898	114	5	curcumin	curcumin	NOUN
mkg-56898	114	6	and	and	CCONJ
mkg-56898	114	7	pgv-0	pgv-0	PUNCT
mkg-56898	114	8	consistently	consistently	ADV
mkg-56898	114	9	showed	show	VERB
mkg-56898	114	10	a	a	DET
mkg-56898	114	11	strong	strong	ADJ
mkg-56898	114	12	relationship	relationship	NOUN
mkg-56898	114	13	with	with	ADP
mkg-56898	114	14	extracellular	extracellular	ADJ
mkg-56898	114	15	matrix	matrix	NOUN
mkg-56898	114	16	metabolism	metabolism	NOUN
mkg-56898	114	17	,	,	PUNCT
mkg-56898	114	18	including	include	VERB
mkg-56898	114	19	collagen	collagen	NOUN
mkg-56898	114	20	processing	processing	NOUN
mkg-56898	114	21	and	and	CCONJ
mkg-56898	114	22	binding	bind	VERB
mkg-56898	114	23	,	,	PUNCT
mkg-56898	114	24	figure	figure	NOUN
mkg-56898	114	25	2	2	NUM
mkg-56898	114	26	.	.	PUNCT
mkg-56898	114	27	visualization	visualization	NOUN
mkg-56898	114	28	of	of	ADP
mkg-56898	114	29	the	the	DET
mkg-56898	114	30	protein	protein	NOUN
mkg-56898	114	31	–	–	PUNCT
mkg-56898	114	32	protein	protein	NOUN
mkg-56898	114	33	interaction	interaction	NOUN
mkg-56898	114	34	from	from	ADP
mkg-56898	114	35	target	target	NOUN
mkg-56898	114	36	predictions	prediction	NOUN
mkg-56898	114	37	of	of	ADP
mkg-56898	114	38	(	(	PUNCT
mkg-56898	114	39	a	a	PRON
mkg-56898	114	40	)	)	PUNCT
mkg-56898	114	41	diclofenac	diclofenac	NOUN
mkg-56898	114	42	sodium	sodium	NOUN
mkg-56898	114	43	,	,	PUNCT
mkg-56898	114	44	(	(	PUNCT
mkg-56898	114	45	b	b	X
mkg-56898	114	46	)	)	PUNCT
mkg-56898	114	47	curcumin	curcumin	NOUN
mkg-56898	114	48	,	,	PUNCT
mkg-56898	114	49	and	and	CCONJ
mkg-56898	114	50	(	(	PUNCT
mkg-56898	114	51	c	c	X
mkg-56898	114	52	)	)	PUNCT
mkg-56898	114	53	pentagamavunon-0	pentagamavunon-0	NOUN
mkg-56898	114	54	using	use	VERB
mkg-56898	114	55	the	the	DET
mkg-56898	114	56	string	string	NOUN
mkg-56898	114	57	tool	tool	NOUN
mkg-56898	114	58	.	.	PUNCT
mkg-56898	115	1	copyright	copyright	NOUN
mkg-56898	115	2	©	©	PROPN
mkg-56898	115	3	2025	2025	NUM
mkg-56898	115	4	dental	dental	ADJ
mkg-56898	115	5	journal	journal	NOUN
mkg-56898	115	6	(	(	PUNCT
mkg-56898	115	7	majalah	majalah	PROPN
mkg-56898	115	8	kedokteran	kedokteran	PROPN
mkg-56898	115	9	gigi	gigi	PROPN
mkg-56898	115	10	)	)	PUNCT
mkg-56898	116	1	p	p	X
mkg-56898	116	2	-	-	PUNCT
mkg-56898	116	3	issn	issn	NOUN
mkg-56898	116	4	:	:	PUNCT
mkg-56898	116	5	1978	1978	NUM
mkg-56898	116	6	-	-	SYM
mkg-56898	116	7	3728	3728	NUM
mkg-56898	116	8	;	;	PUNCT
mkg-56898	116	9	e	e	X
mkg-56898	116	10	-	-	PUNCT
mkg-56898	116	11	issn	issn	ADJ
mkg-56898	116	12	:	:	PUNCT
mkg-56898	116	13	2442	2442	NUM
mkg-56898	116	14	-	-	SYM
mkg-56898	116	15	9740	9740	NUM
mkg-56898	116	16	.	.	PUNCT
mkg-56898	117	1	accredited	accredit	VERB
mkg-56898	117	2	no	no	INTJ
mkg-56898	117	3	.	.	PROPN
mkg-56898	118	1	158	158	NUM
mkg-56898	118	2	/	/	SYM
mkg-56898	118	3	e	e	NOUN
mkg-56898	118	4	/	/	SYM
mkg-56898	118	5	kpt/2021	kpt/2021	NOUN
mkg-56898	118	6	.	.	PUNCT
mkg-56898	119	1	open	open	ADJ
mkg-56898	119	2	access	access	NOUN
mkg-56898	119	3	under	under	ADP
mkg-56898	119	4	cc	cc	NOUN
mkg-56898	119	5	-	-	PUNCT
mkg-56898	119	6	by	by	ADP
mkg-56898	119	7	-	-	PUNCT
mkg-56898	119	8	sa	sa	NOUN
mkg-56898	119	9	license	license	NOUN
mkg-56898	119	10	.	.	PUNCT
mkg-56898	120	1	available	available	ADJ
mkg-56898	120	2	at	at	ADP
mkg-56898	120	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	120	4	doi	doi	NOUN
mkg-56898	120	5	:	:	PUNCT
mkg-56898	120	6	10.20473	10.20473	NUM
mkg-56898	120	7	/	/	SYM
mkg-56898	120	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	PROPN
mkg-56898	120	9	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	120	10	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	121	1	371robin	371robin	PROPN
mkg-56898	121	2	et	et	PROPN
mkg-56898	121	3	al	al	PROPN
mkg-56898	121	4	.	.	PROPN
mkg-56898	121	5	dent	dent	PROPN
mkg-56898	121	6	.	.	PUNCT
mkg-56898	122	1	j.	j.	PROPN
mkg-56898	122	2	(	(	PUNCT
mkg-56898	122	3	majalah	majalah	PROPN
mkg-56898	122	4	kedokteran	kedokteran	PROPN
mkg-56898	122	5	gigi	gigi	PROPN
mkg-56898	122	6	)	)	PUNCT
mkg-56898	122	7	2025	2025	NUM
mkg-56898	122	8	december	december	NOUN
mkg-56898	122	9	;	;	PUNCT
mkg-56898	122	10	58(4	58(4	NUM
mkg-56898	122	11	):	):	PUNCT
mkg-56898	122	12	367–375	367–375	NUM
mkg-56898	122	13	figure	figure	NOUN
mkg-56898	122	14	3	3	NUM
mkg-56898	122	15	.	.	PUNCT
mkg-56898	122	16	gene	gene	NOUN
mkg-56898	122	17	oncology	oncology	NOUN
mkg-56898	122	18	analysis	analysis	NOUN
mkg-56898	122	19	based	base	VERB
mkg-56898	122	20	on	on	ADP
mkg-56898	122	21	the	the	DET
mkg-56898	122	22	molecular	molecular	ADJ
mkg-56898	122	23	function	function	NOUN
mkg-56898	122	24	,	,	PUNCT
mkg-56898	122	25	biological	biological	ADJ
mkg-56898	122	26	process	process	NOUN
mkg-56898	122	27	,	,	PUNCT
mkg-56898	122	28	and	and	CCONJ
mkg-56898	122	29	cellular	cellular	ADJ
mkg-56898	122	30	component	component	NOUN
mkg-56898	122	31	categories	category	NOUN
mkg-56898	122	32	.	.	PUNCT
mkg-56898	123	1	copyright	copyright	NOUN
mkg-56898	123	2	©	©	PROPN
mkg-56898	123	3	2025	2025	NUM
mkg-56898	123	4	dental	dental	ADJ
mkg-56898	123	5	journal	journal	NOUN
mkg-56898	123	6	(	(	PUNCT
mkg-56898	123	7	majalah	majalah	PROPN
mkg-56898	123	8	kedokteran	kedokteran	PROPN
mkg-56898	123	9	gigi	gigi	PROPN
mkg-56898	123	10	)	)	PUNCT
mkg-56898	124	1	p	p	X
mkg-56898	124	2	-	-	PUNCT
mkg-56898	124	3	issn	issn	NOUN
mkg-56898	124	4	:	:	PUNCT
mkg-56898	124	5	1978	1978	NUM
mkg-56898	124	6	-	-	SYM
mkg-56898	124	7	3728	3728	NUM
mkg-56898	124	8	;	;	PUNCT
mkg-56898	124	9	e	e	X
mkg-56898	124	10	-	-	PUNCT
mkg-56898	124	11	issn	issn	ADJ
mkg-56898	124	12	:	:	PUNCT
mkg-56898	124	13	2442	2442	NUM
mkg-56898	124	14	-	-	SYM
mkg-56898	124	15	9740	9740	NUM
mkg-56898	124	16	.	.	PUNCT
mkg-56898	125	1	accredited	accredit	VERB
mkg-56898	125	2	no	no	INTJ
mkg-56898	125	3	.	.	PROPN
mkg-56898	126	1	158	158	NUM
mkg-56898	126	2	/	/	SYM
mkg-56898	126	3	e	e	NOUN
mkg-56898	126	4	/	/	SYM
mkg-56898	126	5	kpt/2021	kpt/2021	NOUN
mkg-56898	126	6	.	.	PUNCT
mkg-56898	127	1	open	open	ADJ
mkg-56898	127	2	access	access	NOUN
mkg-56898	127	3	under	under	ADP
mkg-56898	127	4	cc	cc	NOUN
mkg-56898	127	5	-	-	PUNCT
mkg-56898	127	6	by	by	ADP
mkg-56898	127	7	-	-	PUNCT
mkg-56898	127	8	sa	sa	NOUN
mkg-56898	127	9	license	license	NOUN
mkg-56898	127	10	.	.	PUNCT
mkg-56898	128	1	available	available	ADJ
mkg-56898	128	2	at	at	ADP
mkg-56898	128	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	128	4	doi	doi	NOUN
mkg-56898	128	5	:	:	PUNCT
mkg-56898	128	6	10.20473	10.20473	NUM
mkg-56898	128	7	/	/	SYM
mkg-56898	128	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	PROPN
mkg-56898	128	9	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	128	10	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	129	1	372	372	NUM
mkg-56898	129	2	robin	robin	PROPN
mkg-56898	129	3	et	et	PROPN
mkg-56898	129	4	al	al	PROPN
mkg-56898	129	5	.	.	PROPN
mkg-56898	129	6	dent	dent	PROPN
mkg-56898	129	7	.	.	PUNCT
mkg-56898	130	1	j.	j.	PROPN
mkg-56898	130	2	(	(	PUNCT
mkg-56898	130	3	majalah	majalah	PROPN
mkg-56898	130	4	kedokteran	kedokteran	PROPN
mkg-56898	130	5	gigi	gigi	PROPN
mkg-56898	130	6	)	)	PUNCT
mkg-56898	130	7	2025	2025	NUM
mkg-56898	130	8	december	december	NOUN
mkg-56898	130	9	;	;	PUNCT
mkg-56898	130	10	58(4	58(4	NUM
mkg-56898	130	11	):	):	PUNCT
mkg-56898	130	12	367–375	367–375	NUM
mkg-56898	130	13	as	as	ADV
mkg-56898	130	14	well	well	ADV
mkg-56898	130	15	as	as	ADP
mkg-56898	130	16	metallopeptidase	metallopeptidase	NOUN
mkg-56898	130	17	activity	activity	NOUN
mkg-56898	130	18	.	.	PUNCT
mkg-56898	131	1	this	this	DET
mkg-56898	131	2	finding	finding	NOUN
mkg-56898	131	3	indicates	indicate	VERB
mkg-56898	131	4	that	that	SCONJ
mkg-56898	131	5	curcumin	curcumin	NOUN
mkg-56898	131	6	and	and	CCONJ
mkg-56898	131	7	pgv-0	pgv-0	PUNCT
mkg-56898	131	8	have	have	VERB
mkg-56898	131	9	an	an	DET
mkg-56898	131	10	alternative	alternative	ADJ
mkg-56898	131	11	mechanism	mechanism	NOUN
mkg-56898	131	12	for	for	ADP
mkg-56898	131	13	protecting	protect	VERB
mkg-56898	131	14	the	the	DET
mkg-56898	131	15	integrity	integrity	NOUN
mkg-56898	131	16	of	of	ADP
mkg-56898	131	17	the	the	DET
mkg-56898	131	18	extracellular	extracellular	ADJ
mkg-56898	131	19	matrix	matrix	NOUN
mkg-56898	131	20	.	.	PUNCT
mkg-56898	132	1	this	this	PRON
mkg-56898	132	2	underlined	underline	VERB
mkg-56898	132	3	our	our	PRON
mkg-56898	132	4	gene	gene	NOUN
mkg-56898	132	5	target	target	NOUN
mkg-56898	132	6	analysis	analysis	NOUN
mkg-56898	132	7	result	result	NOUN
mkg-56898	132	8	that	that	PRON
mkg-56898	132	9	showed	show	VERB
mkg-56898	132	10	curcumin	curcumin	NOUN
mkg-56898	132	11	and	and	CCONJ
mkg-56898	132	12	pgv-0	pgv-0	PUNCT
mkg-56898	132	13	targeted	target	VERB
mkg-56898	132	14	mmp	mmp	PROPN
mkg-56898	132	15	gene	gene	NOUN
mkg-56898	132	16	expression	expression	NOUN
mkg-56898	132	17	.	.	PUNCT
mkg-56898	133	1	we	we	PRON
mkg-56898	133	2	hypothesized	hypothesize	VERB
mkg-56898	133	3	that	that	SCONJ
mkg-56898	133	4	both	both	DET
mkg-56898	133	5	curcumin	curcumin	NOUN
mkg-56898	133	6	and	and	CCONJ
mkg-56898	133	7	pgv-0	pgv-0	PUNCT
mkg-56898	133	8	provide	provide	VERB
mkg-56898	133	9	more	more	ADJ
mkg-56898	133	10	protection	protection	NOUN
mkg-56898	133	11	against	against	ADP
mkg-56898	133	12	cartilage	cartilage	NOUN
mkg-56898	133	13	tissue	tissue	NOUN
mkg-56898	133	14	damage	damage	NOUN
mkg-56898	133	15	due	due	ADP
mkg-56898	133	16	to	to	ADP
mkg-56898	133	17	arthritis	arthritis	NOUN
mkg-56898	133	18	in	in	ADP
mkg-56898	133	19	the	the	DET
mkg-56898	133	20	tmj	tmj	NOUN
mkg-56898	133	21	compared	compare	VERB
mkg-56898	133	22	to	to	PART
mkg-56898	133	23	diclofenac	diclofenac	VERB
mkg-56898	133	24	sodium	sodium	NOUN
mkg-56898	133	25	.	.	PUNCT
mkg-56898	134	1	we	we	PRON
mkg-56898	134	2	considered	consider	VERB
mkg-56898	134	3	simulating	simulate	VERB
mkg-56898	134	4	the	the	DET
mkg-56898	134	5	interaction	interaction	NOUN
mkg-56898	134	6	of	of	ADP
mkg-56898	134	7	diclofenac	diclofenac	ADJ
mkg-56898	134	8	sodium	sodium	NOUN
mkg-56898	134	9	,	,	PUNCT
mkg-56898	134	10	curcumin	curcumin	NOUN
mkg-56898	134	11	,	,	PUNCT
mkg-56898	134	12	and	and	CCONJ
mkg-56898	134	13	pgv-0	pgv-0	PUNCT
mkg-56898	134	14	with	with	ADP
mkg-56898	134	15	inflammatory	inflammatory	ADJ
mkg-56898	134	16	and	and	CCONJ
mkg-56898	134	17	tissue	tissue	NOUN
mkg-56898	134	18	destruction	destruction	NOUN
mkg-56898	134	19	markers	marker	NOUN
mkg-56898	134	20	related	relate	VERB
mkg-56898	134	21	to	to	ADP
mkg-56898	134	22	temporomandibular	temporomandibular	ADJ
mkg-56898	134	23	arthritis	arthritis	NOUN
mkg-56898	134	24	,	,	PUNCT
mkg-56898	134	25	ptgs2	ptgs2	PROPN
mkg-56898	134	26	,	,	PUNCT
mkg-56898	134	27	mapk-1	mapk-1	NUM
mkg-56898	134	28	,	,	PUNCT
mkg-56898	134	29	and	and	CCONJ
mkg-56898	134	30	mmp-13	mmp-13	PROPN
mkg-56898	134	31	,	,	PUNCT
mkg-56898	134	32	using	use	VERB
mkg-56898	134	33	the	the	DET
mkg-56898	134	34	molecular	molecular	ADJ
mkg-56898	134	35	docking	docking	NOUN
mkg-56898	134	36	approach	approach	NOUN
mkg-56898	134	37	.	.	PUNCT
mkg-56898	135	1	to	to	PART
mkg-56898	135	2	compare	compare	VERB
mkg-56898	135	3	the	the	DET
mkg-56898	135	4	potential	potential	ADJ
mkg-56898	135	5	collateral	collateral	ADJ
mkg-56898	135	6	impact	impact	NOUN
mkg-56898	135	7	of	of	ADP
mkg-56898	135	8	the	the	DET
mkg-56898	135	9	anti	anti	ADJ
mkg-56898	135	10	-	-	ADJ
mkg-56898	135	11	inflammatory	inflammatory	ADJ
mkg-56898	135	12	activity	activity	NOUN
mkg-56898	135	13	on	on	ADP
mkg-56898	135	14	platelet	platelet	NOUN
mkg-56898	135	15	and	and	CCONJ
mkg-56898	135	16	gut	gut	NOUN
mkg-56898	135	17	protection	protection	NOUN
mkg-56898	135	18	function	function	NOUN
mkg-56898	135	19	,	,	PUNCT
mkg-56898	135	20	we	we	PRON
mkg-56898	135	21	evaluated	evaluate	VERB
mkg-56898	135	22	the	the	DET
mkg-56898	135	23	interaction	interaction	NOUN
mkg-56898	135	24	of	of	ADP
mkg-56898	135	25	all	all	DET
mkg-56898	135	26	agents	agent	NOUN
mkg-56898	135	27	with	with	ADP
mkg-56898	135	28	ptgs1	ptgs1	NOUN
mkg-56898	135	29	(	(	PUNCT
mkg-56898	135	30	figures	figure	NOUN
mkg-56898	135	31	5	5	NUM
mkg-56898	135	32	)	)	PUNCT
mkg-56898	135	33	.	.	PUNCT
mkg-56898	136	1	furthermore	furthermore	ADV
mkg-56898	136	2	,	,	PUNCT
mkg-56898	136	3	we	we	PRON
mkg-56898	136	4	compared	compare	VERB
mkg-56898	136	5	the	the	DET
mkg-56898	136	6	docking	docking	NOUN
mkg-56898	136	7	score	score	NOUN
mkg-56898	136	8	to	to	PART
mkg-56898	136	9	describe	describe	VERB
mkg-56898	136	10	the	the	DET
mkg-56898	136	11	binding	bind	VERB
mkg-56898	136	12	affinity	affinity	NOUN
mkg-56898	136	13	between	between	ADP
mkg-56898	136	14	ligand	ligand	NOUN
mkg-56898	136	15	and	and	CCONJ
mkg-56898	136	16	target	target	NOUN
mkg-56898	136	17	(	(	PUNCT
mkg-56898	136	18	table	table	NOUN
mkg-56898	136	19	1	1	NUM
mkg-56898	136	20	)	)	PUNCT
mkg-56898	136	21	.	.	PUNCT
mkg-56898	137	1	the	the	DET
mkg-56898	137	2	molecular	molecular	ADJ
mkg-56898	137	3	docking	docking	NOUN
mkg-56898	137	4	results	result	NOUN
mkg-56898	137	5	based	base	VERB
mkg-56898	137	6	on	on	ADP
mkg-56898	137	7	analysis	analysis	NOUN
mkg-56898	137	8	in	in	ADP
mkg-56898	137	9	moe	moe	NOUN
mkg-56898	137	10	(	(	PUNCT
mkg-56898	137	11	table	table	NOUN
mkg-56898	137	12	1	1	NUM
mkg-56898	137	13	)	)	PUNCT
mkg-56898	137	14	showed	show	VERB
mkg-56898	137	15	a	a	DET
mkg-56898	137	16	more	more	ADV
mkg-56898	137	17	stable	stable	ADJ
mkg-56898	137	18	interaction	interaction	NOUN
mkg-56898	137	19	between	between	ADP
mkg-56898	137	20	mapk-1	mapk-1	NUM
mkg-56898	137	21	and	and	CCONJ
mkg-56898	137	22	cox-2	cox-2	ADV
mkg-56898	137	23	with	with	ADP
mkg-56898	137	24	curcumin	curcumin	NOUN
mkg-56898	137	25	or	or	CCONJ
mkg-56898	137	26	pgv-0	pgv-0	PUNCT
mkg-56898	137	27	than	than	ADP
mkg-56898	137	28	with	with	ADP
mkg-56898	137	29	diclofenac	diclofenac	ADJ
mkg-56898	137	30	sodium	sodium	NOUN
mkg-56898	137	31	.	.	PUNCT
mkg-56898	138	1	the	the	DET
mkg-56898	138	2	free	free	ADJ
mkg-56898	138	3	energy	energy	NOUN
mkg-56898	138	4	of	of	ADP
mkg-56898	138	5	binding	bind	VERB
mkg-56898	138	6	between	between	ADP
mkg-56898	138	7	mmp-13	mmp-13	PROPN
mkg-56898	138	8	and	and	CCONJ
mkg-56898	138	9	curcumin	curcumin	NOUN
mkg-56898	138	10	or	or	CCONJ
mkg-56898	138	11	pgv-0	pgv-0	PUNCT
mkg-56898	138	12	was	be	AUX
mkg-56898	138	13	shown	show	VERB
mkg-56898	138	14	to	to	PART
mkg-56898	138	15	be	be	AUX
mkg-56898	138	16	more	more	ADV
mkg-56898	138	17	negative	negative	ADJ
mkg-56898	138	18	than	than	ADP
mkg-56898	138	19	with	with	ADP
mkg-56898	138	20	diclofenac	diclofenac	ADJ
mkg-56898	138	21	sodium	sodium	NOUN
mkg-56898	138	22	.	.	PUNCT
mkg-56898	139	1	this	this	PRON
mkg-56898	139	2	indicates	indicate	VERB
mkg-56898	139	3	that	that	SCONJ
mkg-56898	139	4	curcumin	curcumin	NOUN
mkg-56898	139	5	and	and	CCONJ
mkg-56898	139	6	pgv-0	pgv-0	PUNCT
mkg-56898	139	7	might	might	AUX
mkg-56898	139	8	provide	provide	VERB
mkg-56898	139	9	better	well	ADJ
mkg-56898	139	10	inflammatory	inflammatory	ADJ
mkg-56898	139	11	control	control	NOUN
mkg-56898	139	12	.	.	PUNCT
mkg-56898	140	1	however	however	ADV
mkg-56898	140	2	,	,	PUNCT
mkg-56898	140	3	a	a	DET
mkg-56898	140	4	recent	recent	ADJ
mkg-56898	140	5	meta	meta	ADJ
mkg-56898	140	6	-	-	PUNCT
mkg-56898	140	7	analysis	analysis	NOUN
mkg-56898	140	8	study	study	NOUN
mkg-56898	140	9	failed	fail	VERB
mkg-56898	140	10	to	to	PART
mkg-56898	140	11	provide	provide	VERB
mkg-56898	140	12	evidence	evidence	NOUN
mkg-56898	140	13	that	that	SCONJ
mkg-56898	140	14	curcumin	curcumin	NOUN
mkg-56898	140	15	has	have	AUX
mkg-56898	140	16	a	a	DET
mkg-56898	140	17	superior	superior	ADJ
mkg-56898	140	18	antiinflammatory	antiinflammatory	NOUN
mkg-56898	140	19	effect	effect	NOUN
mkg-56898	140	20	compared	compare	VERB
mkg-56898	140	21	to	to	PART
mkg-56898	140	22	diclofenac	diclofenac	VERB
mkg-56898	140	23	sodium	sodium	NOUN
mkg-56898	140	24	due	due	ADP
mkg-56898	140	25	to	to	ADP
mkg-56898	140	26	a	a	DET
mkg-56898	140	27	lack	lack	NOUN
mkg-56898	140	28	of	of	ADP
mkg-56898	140	29	data.25	data.25	NOUN
mkg-56898	140	30	this	this	DET
mkg-56898	140	31	lack	lack	NOUN
mkg-56898	140	32	calls	call	VERB
mkg-56898	140	33	for	for	ADP
mkg-56898	140	34	future	future	ADJ
mkg-56898	140	35	unbiased	unbiased	ADJ
mkg-56898	140	36	randomized	randomize	VERB
mkg-56898	140	37	clinical	clinical	ADJ
mkg-56898	140	38	trials	trial	NOUN
mkg-56898	140	39	.	.	PUNCT
mkg-56898	141	1	regarding	regard	VERB
mkg-56898	141	2	this	this	DET
mkg-56898	141	3	suggestion	suggestion	NOUN
mkg-56898	141	4	,	,	PUNCT
mkg-56898	141	5	figure	figure	NOUN
mkg-56898	141	6	4	4	NUM
mkg-56898	141	7	.	.	PUNCT
mkg-56898	141	8	enrichment	enrichment	NOUN
mkg-56898	141	9	analysis	analysis	NOUN
mkg-56898	141	10	based	base	VERB
mkg-56898	141	11	on	on	ADP
mkg-56898	141	12	the	the	DET
mkg-56898	141	13	kegg	kegg	NOUN
mkg-56898	141	14	pathway	pathway	NOUN
mkg-56898	141	15	for	for	ADP
mkg-56898	141	16	(	(	PUNCT
mkg-56898	141	17	a	a	PRON
mkg-56898	141	18	)	)	PUNCT
mkg-56898	141	19	diclofenac	diclofenac	NOUN
mkg-56898	141	20	sodium	sodium	NOUN
mkg-56898	141	21	,	,	PUNCT
mkg-56898	141	22	(	(	PUNCT
mkg-56898	141	23	b	b	X
mkg-56898	141	24	)	)	PUNCT
mkg-56898	141	25	curcumin	curcumin	NOUN
mkg-56898	141	26	,	,	PUNCT
mkg-56898	141	27	and	and	CCONJ
mkg-56898	141	28	(	(	PUNCT
mkg-56898	141	29	c	c	NOUN
mkg-56898	141	30	)	)	PUNCT
mkg-56898	141	31	pentagamavunon-0	pentagamavunon-0	X
mkg-56898	141	32	(	(	PUNCT
mkg-56898	141	33	pgv-0	pgv-0	NOUN
mkg-56898	141	34	)	)	PUNCT
mkg-56898	141	35	.	.	PUNCT
mkg-56898	142	1	copyright	copyright	NOUN
mkg-56898	142	2	©	©	PROPN
mkg-56898	142	3	2025	2025	NUM
mkg-56898	142	4	dental	dental	ADJ
mkg-56898	142	5	journal	journal	NOUN
mkg-56898	142	6	(	(	PUNCT
mkg-56898	142	7	majalah	majalah	PROPN
mkg-56898	142	8	kedokteran	kedokteran	PROPN
mkg-56898	142	9	gigi	gigi	PROPN
mkg-56898	142	10	)	)	PUNCT
mkg-56898	143	1	p	p	X
mkg-56898	143	2	-	-	PUNCT
mkg-56898	143	3	issn	issn	NOUN
mkg-56898	143	4	:	:	PUNCT
mkg-56898	143	5	1978	1978	NUM
mkg-56898	143	6	-	-	SYM
mkg-56898	143	7	3728	3728	NUM
mkg-56898	143	8	;	;	PUNCT
mkg-56898	143	9	e	e	X
mkg-56898	143	10	-	-	PUNCT
mkg-56898	143	11	issn	issn	ADJ
mkg-56898	143	12	:	:	PUNCT
mkg-56898	143	13	2442	2442	NUM
mkg-56898	143	14	-	-	SYM
mkg-56898	143	15	9740	9740	NUM
mkg-56898	143	16	.	.	PUNCT
mkg-56898	144	1	accredited	accredit	VERB
mkg-56898	144	2	no	no	INTJ
mkg-56898	144	3	.	.	PROPN
mkg-56898	145	1	158	158	NUM
mkg-56898	145	2	/	/	SYM
mkg-56898	145	3	e	e	NOUN
mkg-56898	145	4	/	/	SYM
mkg-56898	145	5	kpt/2021	kpt/2021	NOUN
mkg-56898	145	6	.	.	PUNCT
mkg-56898	146	1	open	open	ADJ
mkg-56898	146	2	access	access	NOUN
mkg-56898	146	3	under	under	ADP
mkg-56898	146	4	cc	cc	NOUN
mkg-56898	146	5	-	-	PUNCT
mkg-56898	146	6	by	by	ADP
mkg-56898	146	7	-	-	PUNCT
mkg-56898	146	8	sa	sa	NOUN
mkg-56898	146	9	license	license	NOUN
mkg-56898	146	10	.	.	PUNCT
mkg-56898	147	1	available	available	ADJ
mkg-56898	147	2	at	at	ADP
mkg-56898	147	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	147	4	doi	doi	NOUN
mkg-56898	147	5	:	:	PUNCT
mkg-56898	147	6	10.20473	10.20473	NUM
mkg-56898	147	7	/	/	SYM
mkg-56898	147	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	PROPN
mkg-56898	147	9	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	147	10	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	148	1	373robin	373robin	PROPN
mkg-56898	148	2	et	et	PROPN
mkg-56898	148	3	al	al	PROPN
mkg-56898	148	4	.	.	PROPN
mkg-56898	148	5	dent	dent	PROPN
mkg-56898	148	6	.	.	PUNCT
mkg-56898	149	1	j.	j.	PROPN
mkg-56898	149	2	(	(	PUNCT
mkg-56898	149	3	majalah	majalah	PROPN
mkg-56898	149	4	kedokteran	kedokteran	PROPN
mkg-56898	149	5	gigi	gigi	PROPN
mkg-56898	149	6	)	)	PUNCT
mkg-56898	149	7	2025	2025	NUM
mkg-56898	149	8	december	december	NOUN
mkg-56898	149	9	;	;	PUNCT
mkg-56898	149	10	58(4	58(4	NUM
mkg-56898	149	11	):	):	PUNCT
mkg-56898	149	12	367–375	367–375	NUM
mkg-56898	149	13	figure	figure	NOUN
mkg-56898	149	14	5	5	NUM
mkg-56898	149	15	.	.	PUNCT
mkg-56898	149	16	three	three	NUM
mkg-56898	149	17	-	-	PUNCT
mkg-56898	149	18	dimensional	dimensional	ADJ
mkg-56898	149	19	visualization	visualization	NOUN
mkg-56898	149	20	for	for	ADP
mkg-56898	149	21	molecular	molecular	ADJ
mkg-56898	149	22	docking	docking	NOUN
mkg-56898	149	23	analysis	analysis	NOUN
mkg-56898	149	24	on	on	ADP
mkg-56898	149	25	diclofenac	diclofenac	ADJ
mkg-56898	149	26	sodium	sodium	NOUN
mkg-56898	149	27	,	,	PUNCT
mkg-56898	149	28	curcumin	curcumin	NOUN
mkg-56898	149	29	,	,	PUNCT
mkg-56898	149	30	and	and	CCONJ
mkg-56898	149	31	pgv-0	pgv-0	PUNCT
mkg-56898	149	32	activity	activity	NOUN
mkg-56898	149	33	toward	toward	ADP
mkg-56898	149	34	ptgs-1	ptgs-1	NOUN
mkg-56898	149	35	,	,	PUNCT
mkg-56898	149	36	ptgs-2	ptgs-2	NUM
mkg-56898	149	37	,	,	PUNCT
mkg-56898	149	38	mapk-1	mapk-1	NUM
mkg-56898	149	39	,	,	PUNCT
mkg-56898	149	40	and	and	CCONJ
mkg-56898	149	41	mmp-13	mmp-13	VERB
mkg-56898	149	42	receptors	receptor	NOUN
mkg-56898	149	43	.	.	PUNCT
mkg-56898	150	1	table	table	NOUN
mkg-56898	150	2	1	1	NUM
mkg-56898	150	3	.	.	PUNCT
mkg-56898	151	1	the	the	DET
mkg-56898	151	2	molecular	molecular	ADJ
mkg-56898	151	3	docking	docking	NOUN
mkg-56898	151	4	results	result	NOUN
mkg-56898	151	5	based	base	VERB
mkg-56898	151	6	on	on	ADP
mkg-56898	151	7	moe	moe	NOUN
mkg-56898	151	8	analysis	analysis	NOUN
mkg-56898	151	9	protein	protein	NOUN
mkg-56898	151	10	pdb	pdb	PROPN
mkg-56898	152	1	i	i	PROPN
mkg-56898	152	2	d	d	PROPN
mkg-56898	152	3	naltive	naltive	PROPN
mkg-56898	152	4	ligand	ligand	PROPN
mkg-56898	152	5	diclofenac	diclofenac	PROPN
mkg-56898	152	6	curcumin	curcumin	PROPN
mkg-56898	152	7	pgv-0	pgv-0	ADV
mkg-56898	152	8	rmsd	rmsd	X
mkg-56898	152	9	(	(	PUNCT
mkg-56898	152	10	å	å	NOUN
mkg-56898	152	11	)	)	PUNCT
mkg-56898	152	12	docking	dock	VERB
mkg-56898	152	13	score	score	NOUN
mkg-56898	152	14	(	(	PUNCT
mkg-56898	152	15	kcal	kcal	NOUN
mkg-56898	152	16	/	/	SYM
mkg-56898	152	17	mol	mol	NOUN
mkg-56898	152	18	)	)	PUNCT
mkg-56898	152	19	docking	dock	VERB
mkg-56898	152	20	score	score	NOUN
mkg-56898	152	21	(	(	PUNCT
mkg-56898	152	22	kcal	kcal	NOUN
mkg-56898	152	23	/	/	SYM
mkg-56898	152	24	mol	mol	NOUN
mkg-56898	152	25	)	)	PUNCT
mkg-56898	152	26	docking	dock	VERB
mkg-56898	152	27	score	score	NOUN
mkg-56898	152	28	(	(	PUNCT
mkg-56898	152	29	kcal	kcal	NOUN
mkg-56898	152	30	/	/	SYM
mkg-56898	152	31	mol	mol	NOUN
mkg-56898	152	32	)	)	PUNCT
mkg-56898	152	33	docking	dock	VERB
mkg-56898	152	34	score	score	NOUN
mkg-56898	152	35	(	(	PUNCT
mkg-56898	152	36	kcal	kcal	NOUN
mkg-56898	152	37	/	/	SYM
mkg-56898	152	38	mol	mol	NOUN
mkg-56898	152	39	)	)	PUNCT
mkg-56898	152	40	mapk-1	mapk-1	NUM
mkg-56898	152	41	5bvd	5bvd	PROPN
mkg-56898	152	42	1.29	1.29	NUM
mkg-56898	152	43	−15.27	−15.27	NOUN
mkg-56898	152	44	−11.34	−11.34	PROPN
mkg-56898	152	45	−13.61	−13.61	NOUN
mkg-56898	152	46	−13.77	−13.77	VERB
mkg-56898	152	47	mmp-13	mmp-13	VERB
mkg-56898	152	48	4jpa	4jpa	PROPN
mkg-56898	153	1	1.38	1.38	NUM
mkg-56898	153	2	−10.84	−10.84	NOUN
mkg-56898	153	3	−9.88	−9.88	INTJ
mkg-56898	154	1	−13.47	−13.47	PROPN
mkg-56898	154	2	−14.39	−14.39	VERB
mkg-56898	154	3	cox-1	cox-1	VERB
mkg-56898	154	4	5wbe	5wbe	NUM
mkg-56898	154	5	0.34	0.34	NUM
mkg-56898	154	6	−14.77	−14.77	ADJ
mkg-56898	154	7	−10.95	−10.95	NOUN
mkg-56898	154	8	−15.12	−15.12	NOUN
mkg-56898	154	9	−16.17	−16.17	ADV
mkg-56898	154	10	cox-2	cox-2	ADV
mkg-56898	154	11	3ln1	3ln1	NUM
mkg-56898	154	12	0.57	0.57	NUM
mkg-56898	155	1	−13.90	−13.90	NOUN
mkg-56898	155	2	−12.26	−12.26	ADJ
mkg-56898	155	3	−20.67	−20.67	NOUN
mkg-56898	155	4	−17.46	−17.46	NOUN
mkg-56898	155	5	figure	figure	VERB
mkg-56898	155	6	6	6	NUM
mkg-56898	155	7	.	.	PUNCT
mkg-56898	156	1	the	the	DET
mkg-56898	156	2	chemical	chemical	NOUN
mkg-56898	156	3	structures	structure	NOUN
mkg-56898	156	4	of	of	ADP
mkg-56898	156	5	(	(	PUNCT
mkg-56898	156	6	a	a	PRON
mkg-56898	156	7	)	)	PUNCT
mkg-56898	156	8	diclofenac	diclofenac	NOUN
mkg-56898	156	9	sodium	sodium	NOUN
mkg-56898	156	10	,	,	PUNCT
mkg-56898	156	11	(	(	PUNCT
mkg-56898	156	12	b	b	X
mkg-56898	156	13	)	)	PUNCT
mkg-56898	156	14	curcumin	curcumin	NOUN
mkg-56898	156	15	,	,	PUNCT
mkg-56898	156	16	and	and	CCONJ
mkg-56898	156	17	(	(	PUNCT
mkg-56898	156	18	c	c	NOUN
mkg-56898	156	19	)	)	PUNCT
mkg-56898	156	20	pentagamavunon-0	pentagamavunon-0	PUNCT
mkg-56898	156	21	.	.	PUNCT
mkg-56898	157	1	copyright	copyright	NOUN
mkg-56898	157	2	©	©	PROPN
mkg-56898	157	3	2025	2025	NUM
mkg-56898	157	4	dental	dental	ADJ
mkg-56898	157	5	journal	journal	NOUN
mkg-56898	157	6	(	(	PUNCT
mkg-56898	157	7	majalah	majalah	PROPN
mkg-56898	157	8	kedokteran	kedokteran	PROPN
mkg-56898	157	9	gigi	gigi	PROPN
mkg-56898	157	10	)	)	PUNCT
mkg-56898	158	1	p	p	X
mkg-56898	158	2	-	-	PUNCT
mkg-56898	158	3	issn	issn	NOUN
mkg-56898	158	4	:	:	PUNCT
mkg-56898	158	5	1978	1978	NUM
mkg-56898	158	6	-	-	SYM
mkg-56898	158	7	3728	3728	NUM
mkg-56898	158	8	;	;	PUNCT
mkg-56898	158	9	e	e	X
mkg-56898	158	10	-	-	PUNCT
mkg-56898	158	11	issn	issn	ADJ
mkg-56898	158	12	:	:	PUNCT
mkg-56898	158	13	2442	2442	NUM
mkg-56898	158	14	-	-	SYM
mkg-56898	158	15	9740	9740	NUM
mkg-56898	158	16	.	.	PUNCT
mkg-56898	159	1	accredited	accredit	VERB
mkg-56898	159	2	no	no	INTJ
mkg-56898	159	3	.	.	PROPN
mkg-56898	160	1	158	158	NUM
mkg-56898	160	2	/	/	SYM
mkg-56898	160	3	e	e	NOUN
mkg-56898	160	4	/	/	SYM
mkg-56898	160	5	kpt/2021	kpt/2021	NOUN
mkg-56898	160	6	.	.	PUNCT
mkg-56898	161	1	open	open	ADJ
mkg-56898	161	2	access	access	NOUN
mkg-56898	161	3	under	under	ADP
mkg-56898	161	4	cc	cc	NOUN
mkg-56898	161	5	-	-	PUNCT
mkg-56898	161	6	by	by	ADP
mkg-56898	161	7	-	-	PUNCT
mkg-56898	161	8	sa	sa	NOUN
mkg-56898	161	9	license	license	NOUN
mkg-56898	161	10	.	.	PUNCT
mkg-56898	162	1	available	available	ADJ
mkg-56898	162	2	at	at	ADP
mkg-56898	162	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	162	4	doi	doi	NOUN
mkg-56898	162	5	:	:	PUNCT
mkg-56898	162	6	10.20473	10.20473	NUM
mkg-56898	162	7	/	/	SYM
mkg-56898	162	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	PROPN
mkg-56898	162	9	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	162	10	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	162	11	374	374	NUM
mkg-56898	162	12	robin	robin	PROPN
mkg-56898	162	13	et	et	PROPN
mkg-56898	162	14	al	al	PROPN
mkg-56898	162	15	.	.	PROPN
mkg-56898	162	16	dent	dent	PROPN
mkg-56898	162	17	.	.	PUNCT
mkg-56898	163	1	j.	j.	PROPN
mkg-56898	163	2	(	(	PUNCT
mkg-56898	163	3	majalah	majalah	PROPN
mkg-56898	163	4	kedokteran	kedokteran	PROPN
mkg-56898	163	5	gigi	gigi	PROPN
mkg-56898	163	6	)	)	PUNCT
mkg-56898	163	7	2025	2025	NUM
mkg-56898	163	8	december	december	NOUN
mkg-56898	163	9	;	;	PUNCT
mkg-56898	163	10	58(4	58(4	NUM
mkg-56898	163	11	):	):	PUNCT
mkg-56898	163	12	367–375	367–375	NUM
mkg-56898	163	13	we	we	PRON
mkg-56898	163	14	also	also	ADV
mkg-56898	163	15	recommended	recommend	VERB
mkg-56898	163	16	evaluating	evaluating	NOUN
mkg-56898	163	17	cox-1	cox-1	X
mkg-56898	163	18	expression	expression	NOUN
mkg-56898	163	19	parameters	parameter	NOUN
mkg-56898	163	20	,	,	PUNCT
mkg-56898	163	21	as	as	SCONJ
mkg-56898	163	22	this	this	DET
mkg-56898	163	23	study	study	NOUN
mkg-56898	163	24	showed	show	VERB
mkg-56898	163	25	that	that	SCONJ
mkg-56898	163	26	the	the	DET
mkg-56898	163	27	more	more	ADV
mkg-56898	163	28	negative	negative	ADJ
mkg-56898	163	29	docking	docking	NOUN
mkg-56898	163	30	score	score	NOUN
mkg-56898	163	31	of	of	ADP
mkg-56898	163	32	the	the	DET
mkg-56898	163	33	interaction	interaction	NOUN
mkg-56898	163	34	between	between	ADP
mkg-56898	163	35	cox-1	cox-1	PUNCT
mkg-56898	163	36	and	and	CCONJ
mkg-56898	163	37	curcumin	curcumin	NOUN
mkg-56898	163	38	,	,	PUNCT
mkg-56898	163	39	or	or	CCONJ
mkg-56898	163	40	pgv-0	pgv-0	PUNCT
mkg-56898	163	41	implies	imply	VERB
mkg-56898	163	42	their	their	PRON
mkg-56898	163	43	potential	potential	NOUN
mkg-56898	163	44	to	to	PART
mkg-56898	163	45	also	also	ADV
mkg-56898	163	46	influence	influence	VERB
mkg-56898	163	47	cox-1	cox-1	NOUN
mkg-56898	163	48	expression	expression	NOUN
mkg-56898	163	49	.	.	PUNCT
mkg-56898	164	1	discussion	discussion	NOUN
mkg-56898	164	2	curcumin	curcumin	NOUN
mkg-56898	164	3	’s	’s	PART
mkg-56898	164	4	low	low	ADJ
mkg-56898	164	5	bioavailability	bioavailability	NOUN
mkg-56898	164	6	hinders	hinder	VERB
mkg-56898	164	7	its	its	PRON
mkg-56898	164	8	development	development	NOUN
mkg-56898	164	9	as	as	ADP
mkg-56898	164	10	an	an	DET
mkg-56898	164	11	oral	oral	ADJ
mkg-56898	164	12	anti	anti	ADJ
mkg-56898	164	13	-	-	ADJ
mkg-56898	164	14	inflammatory	inflammatory	ADJ
mkg-56898	164	15	agent	agent	NOUN
mkg-56898	164	16	.	.	PUNCT
mkg-56898	165	1	hence	hence	ADV
mkg-56898	165	2	,	,	PUNCT
mkg-56898	165	3	pgv-0	pgv-0	PUNCT
mkg-56898	165	4	(	(	PUNCT
mkg-56898	165	5	figure	figure	NOUN
mkg-56898	165	6	6c	6c	PROPN
mkg-56898	165	7	)	)	PUNCT
mkg-56898	165	8	was	be	AUX
mkg-56898	165	9	introduced	introduce	VERB
mkg-56898	165	10	to	to	PART
mkg-56898	165	11	improve	improve	VERB
mkg-56898	165	12	curcumin	curcumin	NOUN
mkg-56898	165	13	’s	’s	PART
mkg-56898	165	14	physicochemical	physicochemical	ADJ
mkg-56898	165	15	properties	property	NOUN
mkg-56898	165	16	,	,	PUNCT
mkg-56898	165	17	increase	increase	VERB
mkg-56898	165	18	its	its	PRON
mkg-56898	165	19	effectiveness	effectiveness	NOUN
mkg-56898	165	20	,	,	PUNCT
mkg-56898	165	21	and	and	CCONJ
mkg-56898	165	22	reduce	reduce	VERB
mkg-56898	165	23	its	its	PRON
mkg-56898	165	24	toxicity	toxicity	NOUN
mkg-56898	165	25	and	and	CCONJ
mkg-56898	165	26	adverse	adverse	ADJ
mkg-56898	165	27	effects.14,15	effects.14,15	NOUN
mkg-56898	165	28	with	with	ADP
mkg-56898	165	29	higher	high	ADJ
mkg-56898	165	30	bioavailability	bioavailability	NOUN
mkg-56898	165	31	,	,	PUNCT
mkg-56898	165	32	pgv-0	pgv-0	PUNCT
mkg-56898	165	33	is	be	AUX
mkg-56898	165	34	expected	expect	VERB
mkg-56898	165	35	to	to	PART
mkg-56898	165	36	provide	provide	VERB
mkg-56898	165	37	optimal	optimal	ADJ
mkg-56898	165	38	therapeutic	therapeutic	ADJ
mkg-56898	165	39	effects	effect	NOUN
mkg-56898	165	40	at	at	ADP
mkg-56898	165	41	lower	low	ADJ
mkg-56898	165	42	doses	dose	NOUN
mkg-56898	165	43	.	.	PUNCT
mkg-56898	166	1	diclofenac	diclofenac	NOUN
mkg-56898	166	2	sodium	sodium	NOUN
mkg-56898	166	3	belongs	belong	VERB
mkg-56898	166	4	to	to	ADP
mkg-56898	166	5	the	the	DET
mkg-56898	166	6	family	family	NOUN
mkg-56898	166	7	of	of	ADP
mkg-56898	166	8	phenylacetic	phenylacetic	ADJ
mkg-56898	166	9	acid	acid	NOUN
mkg-56898	166	10	of	of	ADP
mkg-56898	166	11	nsaids	nsaid	NOUN
mkg-56898	166	12	approved	approve	VERB
mkg-56898	166	13	by	by	ADP
mkg-56898	166	14	the	the	DET
mkg-56898	166	15	food	food	NOUN
mkg-56898	166	16	and	and	CCONJ
mkg-56898	166	17	drug	drug	PROPN
mkg-56898	166	18	administration	administration	NOUN
mkg-56898	166	19	of	of	ADP
mkg-56898	166	20	the	the	DET
mkg-56898	166	21	usa	usa	PROPN
mkg-56898	166	22	to	to	PART
mkg-56898	166	23	treat	treat	VERB
mkg-56898	166	24	arthritis	arthritis	NOUN
mkg-56898	166	25	.	.	PUNCT
mkg-56898	167	1	it	it	PRON
mkg-56898	167	2	inhibits	inhibit	VERB
mkg-56898	167	3	prostanoid	prostanoid	NOUN
mkg-56898	167	4	synthesis	synthesis	NOUN
mkg-56898	167	5	,	,	PUNCT
mkg-56898	167	6	thus	thus	ADV
mkg-56898	167	7	constraining	constrain	VERB
mkg-56898	167	8	the	the	DET
mkg-56898	167	9	cox-2	cox-2	ADJ
mkg-56898	167	10	activity	activity	NOUN
mkg-56898	167	11	and	and	CCONJ
mkg-56898	167	12	preventing	prevent	VERB
mkg-56898	167	13	the	the	DET
mkg-56898	167	14	progression	progression	NOUN
mkg-56898	167	15	of	of	ADP
mkg-56898	167	16	inflammation	inflammation	NOUN
mkg-56898	167	17	.	.	PUNCT
mkg-56898	168	1	however	however	ADV
mkg-56898	168	2	,	,	PUNCT
mkg-56898	168	3	it	it	PRON
mkg-56898	168	4	also	also	ADV
mkg-56898	168	5	halts	halt	VERB
mkg-56898	168	6	cox-1	cox-1	ADJ
mkg-56898	168	7	activity	activity	NOUN
mkg-56898	168	8	,	,	PUNCT
mkg-56898	168	9	which	which	PRON
mkg-56898	168	10	is	be	AUX
mkg-56898	168	11	needed	need	VERB
mkg-56898	168	12	for	for	ADP
mkg-56898	168	13	homeostasis	homeostasis	NOUN
mkg-56898	168	14	,	,	PUNCT
mkg-56898	168	15	especially	especially	ADV
mkg-56898	168	16	related	relate	VERB
mkg-56898	168	17	to	to	ADP
mkg-56898	168	18	platelet	platelet	NOUN
mkg-56898	168	19	activity	activity	NOUN
mkg-56898	168	20	and	and	CCONJ
mkg-56898	168	21	protection	protection	NOUN
mkg-56898	168	22	of	of	ADP
mkg-56898	168	23	the	the	DET
mkg-56898	168	24	gastric	gastric	ADJ
mkg-56898	168	25	mucosa	mucosa	NOUN
mkg-56898	168	26	from	from	ADP
mkg-56898	168	27	acidity	acidity	NOUN
mkg-56898	168	28	.	.	PUNCT
mkg-56898	169	1	although	although	SCONJ
mkg-56898	169	2	diclofenac	diclofenac	ADJ
mkg-56898	169	3	sodium	sodium	NOUN
mkg-56898	169	4	is	be	AUX
mkg-56898	169	5	proven	prove	VERB
mkg-56898	169	6	to	to	PART
mkg-56898	169	7	be	be	AUX
mkg-56898	169	8	more	more	ADV
mkg-56898	169	9	specific	specific	ADJ
mkg-56898	169	10	to	to	ADP
mkg-56898	169	11	cox-2	cox-2	NUM
mkg-56898	169	12	,	,	PUNCT
mkg-56898	169	13	the	the	DET
mkg-56898	169	14	side	side	NOUN
mkg-56898	169	15	effects	effect	NOUN
mkg-56898	169	16	—	—	PUNCT
mkg-56898	169	17	for	for	ADP
mkg-56898	169	18	example	example	NOUN
mkg-56898	169	19	,	,	PUNCT
mkg-56898	169	20	the	the	DET
mkg-56898	169	21	development	development	NOUN
mkg-56898	169	22	of	of	ADP
mkg-56898	169	23	gastritis	gastritis	PROPN
mkg-56898	169	24	caused	cause	VERB
mkg-56898	169	25	by	by	ADP
mkg-56898	169	26	a	a	DET
mkg-56898	169	27	decline	decline	NOUN
mkg-56898	169	28	in	in	ADP
mkg-56898	169	29	the	the	DET
mkg-56898	169	30	protective	protective	ADJ
mkg-56898	169	31	effect	effect	NOUN
mkg-56898	169	32	—	—	PUNCT
mkg-56898	169	33	remain	remain	VERB
mkg-56898	169	34	problematic.26,27	problematic.26,27	NOUN
mkg-56898	169	35	curcumin	curcumin	NOUN
mkg-56898	169	36	(	(	PUNCT
mkg-56898	169	37	figure	figure	NOUN
mkg-56898	169	38	6b	6b	NOUN
mkg-56898	169	39	)	)	PUNCT
mkg-56898	169	40	,	,	PUNCT
mkg-56898	169	41	derived	derive	VERB
mkg-56898	169	42	from	from	ADP
mkg-56898	169	43	turmeric	turmeric	ADJ
mkg-56898	169	44	(	(	PUNCT
mkg-56898	169	45	curcuma	curcuma	PROPN
mkg-56898	169	46	longa	longa	NOUN
mkg-56898	169	47	)	)	PUNCT
mkg-56898	169	48	plants	plant	NOUN
mkg-56898	169	49	,	,	PUNCT
mkg-56898	169	50	is	be	AUX
mkg-56898	169	51	among	among	ADP
mkg-56898	169	52	the	the	DET
mkg-56898	169	53	alternative	alternative	ADJ
mkg-56898	169	54	compounds	compound	NOUN
mkg-56898	169	55	to	to	PART
mkg-56898	169	56	diclofenac	diclofenac	VERB
mkg-56898	169	57	sodium	sodium	NOUN
mkg-56898	169	58	.	.	PUNCT
mkg-56898	170	1	a	a	DET
mkg-56898	170	2	randomized	randomized	ADJ
mkg-56898	170	3	,	,	PUNCT
mkg-56898	170	4	open	open	ADJ
mkg-56898	170	5	-	-	PUNCT
mkg-56898	170	6	label	label	NOUN
mkg-56898	170	7	,	,	PUNCT
mkg-56898	170	8	parallel	parallel	ADJ
mkg-56898	170	9	,	,	PUNCT
mkg-56898	170	10	active	active	ADJ
mkg-56898	170	11	-	-	PUNCT
mkg-56898	170	12	controlled	control	VERB
mkg-56898	170	13	clinical	clinical	ADJ
mkg-56898	170	14	study	study	NOUN
mkg-56898	170	15	of	of	ADP
mkg-56898	170	16	139	139	NUM
mkg-56898	170	17	patients	patient	NOUN
mkg-56898	170	18	with	with	ADP
mkg-56898	170	19	knee	knee	NOUN
mkg-56898	170	20	oa	oa	PRON
mkg-56898	170	21	showed	show	VERB
mkg-56898	170	22	a	a	DET
mkg-56898	170	23	comparable	comparable	ADJ
mkg-56898	170	24	anti	anti	ADJ
mkg-56898	170	25	-	-	ADJ
mkg-56898	170	26	inflammatory	inflammatory	ADJ
mkg-56898	170	27	effect	effect	NOUN
mkg-56898	170	28	of	of	ADP
mkg-56898	170	29	the	the	DET
mkg-56898	170	30	administration	administration	NOUN
mkg-56898	170	31	of	of	ADP
mkg-56898	170	32	500	500	NUM
mkg-56898	170	33	mg	mg	PROPN
mkg-56898	170	34	curcumin	curcumin	NOUN
mkg-56898	170	35	to	to	ADP
mkg-56898	170	36	50	50	NUM
mkg-56898	170	37	mg	mg	PROPN
mkg-56898	170	38	diclofenac	diclofenac	NOUN
mkg-56898	170	39	sodium	sodium	NOUN
mkg-56898	170	40	three	three	NUM
mkg-56898	170	41	times	time	NOUN
mkg-56898	170	42	a	a	DET
mkg-56898	170	43	day	day	NOUN
mkg-56898	170	44	.	.	PUNCT
mkg-56898	171	1	however	however	ADV
mkg-56898	171	2	,	,	PUNCT
mkg-56898	171	3	fewer	few	ADJ
mkg-56898	171	4	adverse	adverse	ADJ
mkg-56898	171	5	effects	effect	NOUN
mkg-56898	171	6	were	be	AUX
mkg-56898	171	7	reported	report	VERB
mkg-56898	171	8	by	by	ADP
mkg-56898	171	9	patients	patient	NOUN
mkg-56898	171	10	who	who	PRON
mkg-56898	171	11	received	receive	VERB
mkg-56898	171	12	curcumin	curcumin	NOUN
mkg-56898	171	13	.	.	PUNCT
mkg-56898	172	1	although	although	SCONJ
mkg-56898	172	2	not	not	PART
mkg-56898	172	3	statistically	statistically	ADV
mkg-56898	172	4	significant	significant	ADJ
mkg-56898	172	5	,	,	PUNCT
mkg-56898	172	6	the	the	DET
mkg-56898	172	7	number	number	NOUN
mkg-56898	172	8	of	of	ADP
mkg-56898	172	9	patients	patient	NOUN
mkg-56898	172	10	who	who	PRON
mkg-56898	172	11	needed	need	VERB
mkg-56898	172	12	acetaminophen	acetaminophen	NOUN
mkg-56898	172	13	rescue	rescue	NOUN
mkg-56898	172	14	was	be	AUX
mkg-56898	172	15	higher	high	ADJ
mkg-56898	172	16	in	in	ADP
mkg-56898	172	17	the	the	DET
mkg-56898	172	18	curcumin	curcumin	NOUN
mkg-56898	172	19	group	group	NOUN
mkg-56898	172	20	than	than	ADP
mkg-56898	172	21	in	in	ADP
mkg-56898	172	22	the	the	DET
mkg-56898	172	23	diclofenac	diclofenac	NOUN
mkg-56898	172	24	sodium	sodium	NOUN
mkg-56898	172	25	group.26,28	group.26,28	NOUN
mkg-56898	172	26	this	this	DET
mkg-56898	172	27	study	study	NOUN
mkg-56898	172	28	indicated	indicate	VERB
mkg-56898	172	29	that	that	SCONJ
mkg-56898	172	30	diclofenac	diclofenac	NOUN
mkg-56898	172	31	sodium	sodium	NOUN
mkg-56898	172	32	,	,	PUNCT
mkg-56898	172	33	curcumin	curcumin	NOUN
mkg-56898	172	34	,	,	PUNCT
mkg-56898	172	35	and	and	CCONJ
mkg-56898	172	36	pgv-0	pgv-0	PUNCT
mkg-56898	172	37	might	might	AUX
mkg-56898	172	38	have	have	VERB
mkg-56898	172	39	different	different	ADJ
mkg-56898	172	40	mechanisms	mechanism	NOUN
mkg-56898	172	41	in	in	ADP
mkg-56898	172	42	temporomandibular	temporomandibular	ADJ
mkg-56898	172	43	arthritis	arthritis	NOUN
mkg-56898	172	44	pathogenesis	pathogenesis	NOUN
mkg-56898	172	45	.	.	PUNCT
mkg-56898	173	1	unlike	unlike	ADP
mkg-56898	173	2	diclofenac	diclofenac	NOUN
mkg-56898	173	3	sodium	sodium	NOUN
mkg-56898	173	4	,	,	PUNCT
mkg-56898	173	5	curcumin	curcumin	NOUN
mkg-56898	173	6	and	and	CCONJ
mkg-56898	173	7	pgv-0	pgv-0	PUNCT
mkg-56898	173	8	targeted	target	VERB
mkg-56898	173	9	matrix	matrix	NOUN
mkg-56898	173	10	metalloproteinases	metalloproteinase	NOUN
mkg-56898	173	11	(	(	PUNCT
mkg-56898	173	12	mmp)-related	mmp)-related	ADJ
mkg-56898	173	13	genes	gene	NOUN
mkg-56898	173	14	,	,	PUNCT
mkg-56898	173	15	mmp-9	mmp-9	NOUN
mkg-56898	173	16	and	and	CCONJ
mkg-56898	173	17	mmp-13	mmp-13	NOUN
mkg-56898	173	18	.	.	PROPN
mkg-56898	173	19	moreover	moreover	ADV
mkg-56898	173	20	,	,	PUNCT
mkg-56898	173	21	curcumin	curcumin	NOUN
mkg-56898	173	22	also	also	ADV
mkg-56898	173	23	targeted	target	VERB
mkg-56898	173	24	mmp-3	mmp-3	NOUN
mkg-56898	173	25	and	and	CCONJ
mkg-56898	173	26	mmp-8	mmp-8	NOUN
mkg-56898	173	27	.	.	PUNCT
mkg-56898	174	1	this	this	DET
mkg-56898	174	2	finding	finding	NOUN
mkg-56898	174	3	was	be	AUX
mkg-56898	174	4	in	in	ADP
mkg-56898	174	5	line	line	NOUN
mkg-56898	174	6	with	with	ADP
mkg-56898	174	7	the	the	DET
mkg-56898	174	8	previous	previous	ADJ
mkg-56898	174	9	experimental	experimental	ADJ
mkg-56898	174	10	research	research	NOUN
mkg-56898	174	11	on	on	ADP
mkg-56898	174	12	curcumin	curcumin	NOUN
mkg-56898	174	13	,	,	PUNCT
mkg-56898	174	14	as	as	SCONJ
mkg-56898	174	15	it	it	PRON
mkg-56898	174	16	played	play	VERB
mkg-56898	174	17	an	an	DET
mkg-56898	174	18	important	important	ADJ
mkg-56898	174	19	role	role	NOUN
mkg-56898	174	20	in	in	ADP
mkg-56898	174	21	regulating	regulate	VERB
mkg-56898	174	22	mmp	mmp	PROPN
mkg-56898	174	23	in	in	ADP
mkg-56898	174	24	the	the	DET
mkg-56898	174	25	pathogenesis	pathogenesis	NOUN
mkg-56898	174	26	of	of	ADP
mkg-56898	174	27	oa	oa	NOUN
mkg-56898	174	28	.	.	PUNCT
mkg-56898	175	1	furthermore	furthermore	ADV
mkg-56898	175	2	,	,	PUNCT
mkg-56898	175	3	mmp-13	mmp-13	PROPN
mkg-56898	175	4	is	be	AUX
mkg-56898	175	5	known	know	VERB
mkg-56898	175	6	to	to	PART
mkg-56898	175	7	be	be	AUX
mkg-56898	175	8	involved	involve	VERB
mkg-56898	175	9	in	in	ADP
mkg-56898	175	10	cartilage	cartilage	NOUN
mkg-56898	175	11	degradation	degradation	NOUN
mkg-56898	175	12	in	in	ADP
mkg-56898	175	13	oa.22	oa.22	NOUN
mkg-56898	175	14	curcumin	curcumin	NOUN
mkg-56898	175	15	has	have	AUX
mkg-56898	175	16	been	be	AUX
mkg-56898	175	17	shown	show	VERB
mkg-56898	175	18	to	to	PART
mkg-56898	175	19	downregulate	downregulate	VERB
mkg-56898	175	20	the	the	DET
mkg-56898	175	21	expression	expression	NOUN
mkg-56898	175	22	of	of	ADP
mkg-56898	175	23	mmp-3	mmp-3	NUM
mkg-56898	175	24	and	and	CCONJ
mkg-56898	175	25	mmp13	mmp13	NOUN
mkg-56898	175	26	in	in	ADP
mkg-56898	175	27	chondrocytes	chondrocyte	NOUN
mkg-56898	175	28	,	,	PUNCT
mkg-56898	175	29	thus	thus	ADV
mkg-56898	175	30	exerting	exert	VERB
mkg-56898	175	31	a	a	DET
mkg-56898	175	32	chondroprotective	chondroprotective	ADJ
mkg-56898	175	33	effect.29	effect.29	NOUN
mkg-56898	175	34	a	a	DET
mkg-56898	175	35	previous	previous	ADJ
mkg-56898	175	36	study	study	NOUN
mkg-56898	175	37	demonstrated	demonstrate	VERB
mkg-56898	175	38	that	that	SCONJ
mkg-56898	175	39	curcumin	curcumin	NOUN
mkg-56898	175	40	inhibits	inhibit	VERB
mkg-56898	175	41	mmp-13	mmp-13	NOUN
mkg-56898	175	42	production	production	NOUN
mkg-56898	175	43	induced	induce	VERB
mkg-56898	175	44	by	by	ADP
mkg-56898	175	45	il-1β	il-1β	PROPN
mkg-56898	175	46	in	in	ADP
mkg-56898	175	47	articular	articular	ADJ
mkg-56898	175	48	chondrocytes	chondrocyte	NOUN
mkg-56898	175	49	by	by	ADP
mkg-56898	175	50	suppressing	suppress	VERB
mkg-56898	175	51	the	the	DET
mkg-56898	175	52	nf	nf	NOUN
mkg-56898	175	53	-	-	PUNCT
mkg-56898	175	54	κb	κb	NOUN
mkg-56898	175	55	pathway.30	pathway.30	NOUN
mkg-56898	175	56	in	in	ADP
mkg-56898	175	57	the	the	DET
mkg-56898	175	58	case	case	NOUN
mkg-56898	175	59	of	of	ADP
mkg-56898	175	60	the	the	DET
mkg-56898	175	61	predicted	predict	VERB
mkg-56898	175	62	target	target	NOUN
mkg-56898	175	63	of	of	ADP
mkg-56898	175	64	diclofenac	diclofenac	ADJ
mkg-56898	175	65	sodium	sodium	NOUN
mkg-56898	175	66	,	,	PUNCT
mkg-56898	175	67	it	it	PRON
mkg-56898	175	68	was	be	AUX
mkg-56898	175	69	found	find	VERB
mkg-56898	175	70	that	that	SCONJ
mkg-56898	175	71	the	the	DET
mkg-56898	175	72	mapk-1	mapk-1	NUM
mkg-56898	175	73	gene	gene	NOUN
mkg-56898	175	74	was	be	AUX
mkg-56898	175	75	only	only	ADV
mkg-56898	175	76	being	be	AUX
mkg-56898	175	77	targeted	target	VERB
mkg-56898	175	78	by	by	ADP
mkg-56898	175	79	the	the	DET
mkg-56898	175	80	diclofenac	diclofenac	NOUN
mkg-56898	175	81	sodium	sodium	NOUN
mkg-56898	175	82	.	.	PUNCT
mkg-56898	176	1	however	however	ADV
mkg-56898	176	2	,	,	PUNCT
mkg-56898	176	3	another	another	DET
mkg-56898	176	4	study	study	NOUN
mkg-56898	176	5	reported	report	VERB
mkg-56898	176	6	that	that	SCONJ
mkg-56898	176	7	curcumin	curcumin	NOUN
mkg-56898	176	8	stimulates	stimulate	VERB
mkg-56898	176	9	the	the	DET
mkg-56898	176	10	mapk	mapk	NOUN
mkg-56898	176	11	pathway	pathway	NOUN
mkg-56898	176	12	of	of	ADP
mkg-56898	176	13	human	human	ADJ
mkg-56898	176	14	articular	articular	NOUN
mkg-56898	176	15	chondrocytes.31	chondrocytes.31	VERB
mkg-56898	176	16	the	the	DET
mkg-56898	176	17	overall	overall	ADJ
mkg-56898	176	18	finding	finding	NOUN
mkg-56898	176	19	of	of	ADP
mkg-56898	176	20	this	this	DET
mkg-56898	176	21	study	study	NOUN
mkg-56898	176	22	predicts	predict	VERB
mkg-56898	176	23	the	the	DET
mkg-56898	176	24	potential	potential	NOUN
mkg-56898	176	25	of	of	ADP
mkg-56898	176	26	pgv-0	pgv-0	PUNCT
mkg-56898	176	27	as	as	ADP
mkg-56898	176	28	an	an	DET
mkg-56898	176	29	anti	anti	ADJ
mkg-56898	176	30	-	-	ADJ
mkg-56898	176	31	inflammatory	inflammatory	ADJ
mkg-56898	176	32	and	and	CCONJ
mkg-56898	176	33	protective	protective	ADJ
mkg-56898	176	34	agent	agent	NOUN
mkg-56898	176	35	against	against	ADP
mkg-56898	176	36	cartilage	cartilage	NOUN
mkg-56898	176	37	degradation	degradation	NOUN
mkg-56898	176	38	in	in	ADP
mkg-56898	176	39	tmjs	tmj	NOUN
mkg-56898	176	40	.	.	PUNCT
mkg-56898	177	1	using	use	VERB
mkg-56898	177	2	the	the	DET
mkg-56898	177	3	bioinformatics	bioinformatics	NOUN
mkg-56898	177	4	approach	approach	NOUN
mkg-56898	177	5	,	,	PUNCT
mkg-56898	177	6	we	we	PRON
mkg-56898	177	7	showed	show	VERB
mkg-56898	177	8	that	that	SCONJ
mkg-56898	177	9	pgv-0	pgv-0	PUNCT
mkg-56898	177	10	shared	share	VERB
mkg-56898	177	11	a	a	DET
mkg-56898	177	12	similar	similar	ADJ
mkg-56898	177	13	mechanism	mechanism	NOUN
mkg-56898	177	14	with	with	ADP
mkg-56898	177	15	curcumin	curcumin	NOUN
mkg-56898	177	16	but	but	CCONJ
mkg-56898	177	17	was	be	AUX
mkg-56898	177	18	different	different	ADJ
mkg-56898	177	19	from	from	ADP
mkg-56898	177	20	diclofenac	diclofenac	ADJ
mkg-56898	177	21	sodium	sodium	NOUN
mkg-56898	177	22	.	.	PUNCT
mkg-56898	178	1	several	several	ADJ
mkg-56898	178	2	studies	study	NOUN
mkg-56898	178	3	have	have	AUX
mkg-56898	178	4	reported	report	VERB
mkg-56898	178	5	increased	increased	ADJ
mkg-56898	178	6	levels	level	NOUN
mkg-56898	178	7	of	of	ADP
mkg-56898	178	8	mmp-9	mmp-9	ADJ
mkg-56898	178	9	and	and	CCONJ
mkg-56898	178	10	mmp-13	mmp-13	PROPN
mkg-56898	178	11	in	in	ADP
mkg-56898	178	12	the	the	DET
mkg-56898	178	13	synovial	synovial	ADJ
mkg-56898	178	14	fluid	fluid	NOUN
mkg-56898	178	15	of	of	ADP
mkg-56898	178	16	patients	patient	NOUN
mkg-56898	178	17	with	with	ADP
mkg-56898	178	18	temporomandibular	temporomandibular	ADJ
mkg-56898	178	19	arthritis	arthritis	NOUN
mkg-56898	178	20	compared	compare	VERB
mkg-56898	178	21	to	to	ADP
mkg-56898	178	22	healthy	healthy	ADJ
mkg-56898	178	23	individuals.22,32	individuals.22,32	NOUN
mkg-56898	178	24	mmp-9	mmp-9	NOUN
mkg-56898	178	25	breaks	break	NOUN
mkg-56898	178	26	down	down	ADP
mkg-56898	178	27	collagen	collagen	NOUN
mkg-56898	178	28	types	type	NOUN
mkg-56898	178	29	iv	iv	ADP
mkg-56898	178	30	and	and	CCONJ
mkg-56898	178	31	v	v	NOUN
mkg-56898	178	32	,	,	PUNCT
mkg-56898	178	33	allowing	allow	VERB
mkg-56898	178	34	for	for	ADP
mkg-56898	178	35	immune	immune	ADJ
mkg-56898	178	36	cell	cell	NOUN
mkg-56898	178	37	migration	migration	NOUN
mkg-56898	178	38	and	and	CCONJ
mkg-56898	178	39	inflammation	inflammation	NOUN
mkg-56898	178	40	in	in	ADP
mkg-56898	178	41	the	the	DET
mkg-56898	178	42	tmj	tmj	NOUN
mkg-56898	178	43	.	.	PUNCT
mkg-56898	179	1	meanwhile	meanwhile	ADV
mkg-56898	179	2	,	,	PUNCT
mkg-56898	179	3	mmp-13	mmp-13	PROPN
mkg-56898	179	4	cleaves	cleave	VERB
mkg-56898	179	5	key	key	ADJ
mkg-56898	179	6	collagen	collagen	NOUN
mkg-56898	179	7	types	type	NOUN
mkg-56898	179	8	ii	ii	PROPN
mkg-56898	179	9	and	and	CCONJ
mkg-56898	179	10	iii	iii	NUM
mkg-56898	179	11	in	in	ADP
mkg-56898	179	12	cartilage	cartilage	NOUN
mkg-56898	179	13	tissue	tissue	NOUN
mkg-56898	179	14	.	.	PUNCT
mkg-56898	180	1	developing	develop	VERB
mkg-56898	180	2	targeted	target	VERB
mkg-56898	180	3	therapies	therapy	NOUN
mkg-56898	180	4	against	against	ADP
mkg-56898	180	5	mmp-9	mmp-9	NOUN
mkg-56898	180	6	and	and	CCONJ
mkg-56898	180	7	mmp-13	mmp-13	NOUN
mkg-56898	180	8	may	may	AUX
mkg-56898	180	9	alleviate	alleviate	VERB
mkg-56898	180	10	tmj	tmj	NOUN
mkg-56898	180	11	arthritis	arthritis	NOUN
mkg-56898	180	12	symptoms	symptom	NOUN
mkg-56898	180	13	and	and	CCONJ
mkg-56898	180	14	impede	impede	VERB
mkg-56898	180	15	further	further	ADJ
mkg-56898	180	16	advancement	advancement	NOUN
mkg-56898	180	17	of	of	ADP
mkg-56898	180	18	this	this	DET
mkg-56898	180	19	debilitating	debilitate	VERB
mkg-56898	180	20	condition	condition	NOUN
mkg-56898	180	21	.	.	PUNCT
mkg-56898	181	1	in	in	ADP
mkg-56898	181	2	addition	addition	NOUN
mkg-56898	181	3	to	to	ADP
mkg-56898	181	4	mmp	mmp	PROPN
mkg-56898	181	5	,	,	PUNCT
mkg-56898	181	6	coexpression	coexpression	NOUN
mkg-56898	181	7	and	and	CCONJ
mkg-56898	181	8	co	co	NOUN
mkg-56898	181	9	-	-	NOUN
mkg-56898	181	10	concurrence	concurrence	NOUN
mkg-56898	181	11	of	of	ADP
mkg-56898	181	12	innate	innate	ADJ
mkg-56898	181	13	and	and	CCONJ
mkg-56898	181	14	adaptive	adaptive	ADJ
mkg-56898	181	15	immune	immune	ADJ
mkg-56898	181	16	function	function	NOUN
mkg-56898	181	17	of	of	ADP
mkg-56898	181	18	tnf	tnf	PROPN
mkg-56898	181	19	,	,	PUNCT
mkg-56898	181	20	lyn	lyn	PROPN
mkg-56898	181	21	,	,	PUNCT
mkg-56898	181	22	and	and	CCONJ
mkg-56898	181	23	bcl-2	bcl-2	NOUN
mkg-56898	181	24	genes	gene	NOUN
mkg-56898	181	25	were	be	AUX
mkg-56898	181	26	found	find	VERB
mkg-56898	181	27	in	in	ADP
mkg-56898	181	28	pgv-0	pgv-0	NOUN
mkg-56898	181	29	.	.	PUNCT
mkg-56898	182	1	this	this	PRON
mkg-56898	182	2	indicates	indicate	VERB
mkg-56898	182	3	that	that	SCONJ
mkg-56898	182	4	pgv-0	pgv-0	PUNCT
mkg-56898	182	5	orchestrated	orchestrate	VERB
mkg-56898	182	6	the	the	DET
mkg-56898	182	7	inflammatory	inflammatory	ADJ
mkg-56898	182	8	response	response	NOUN
mkg-56898	182	9	,	,	PUNCT
mkg-56898	182	10	providing	provide	VERB
mkg-56898	182	11	an	an	DET
mkg-56898	182	12	additional	additional	ADJ
mkg-56898	182	13	effect	effect	NOUN
mkg-56898	182	14	from	from	ADP
mkg-56898	182	15	curcumin	curcumin	NOUN
mkg-56898	182	16	.	.	PUNCT
mkg-56898	183	1	a	a	DET
mkg-56898	183	2	previous	previous	ADJ
mkg-56898	183	3	study	study	NOUN
mkg-56898	183	4	reported	report	VERB
mkg-56898	183	5	that	that	SCONJ
mkg-56898	183	6	diclofenac	diclofenac	NOUN
mkg-56898	183	7	sodium	sodium	NOUN
mkg-56898	183	8	,	,	PUNCT
mkg-56898	183	9	curcumin	curcumin	NOUN
mkg-56898	183	10	,	,	PUNCT
mkg-56898	183	11	and	and	CCONJ
mkg-56898	183	12	pgv-0	pgv-0	PUNCT
mkg-56898	183	13	exhibit	exhibit	VERB
mkg-56898	183	14	anti	anti	ADJ
mkg-56898	183	15	-	-	ADJ
mkg-56898	183	16	inflammatory	inflammatory	ADJ
mkg-56898	183	17	and	and	CCONJ
mkg-56898	183	18	analgesic	analgesic	ADJ
mkg-56898	183	19	properties.10,15,33	properties.10,15,33	ADP
mkg-56898	183	20	however	however	ADV
mkg-56898	183	21	,	,	PUNCT
mkg-56898	183	22	according	accord	VERB
mkg-56898	183	23	to	to	ADP
mkg-56898	183	24	the	the	DET
mkg-56898	183	25	kegg	kegg	NOUN
mkg-56898	183	26	enrichment	enrichment	NOUN
mkg-56898	183	27	analysis	analysis	NOUN
mkg-56898	183	28	(	(	PUNCT
mkg-56898	183	29	figure	figure	NOUN
mkg-56898	183	30	6	6	NUM
mkg-56898	183	31	)	)	PUNCT
mkg-56898	183	32	,	,	PUNCT
mkg-56898	183	33	diclofenac	diclofenac	NOUN
mkg-56898	183	34	sodium	sodium	NOUN
mkg-56898	183	35	has	have	VERB
mkg-56898	183	36	a	a	DET
mkg-56898	183	37	different	different	ADJ
mkg-56898	183	38	mechanism	mechanism	NOUN
mkg-56898	183	39	from	from	ADP
mkg-56898	183	40	curcumin	curcumin	NOUN
mkg-56898	183	41	and	and	CCONJ
mkg-56898	183	42	pgv-0	pgv-0	PUNCT
mkg-56898	183	43	in	in	ADP
mkg-56898	183	44	temporomandibular	temporomandibular	ADJ
mkg-56898	183	45	arthritis	arthritis	NOUN
mkg-56898	183	46	.	.	PUNCT
mkg-56898	184	1	diclofenac	diclofenac	NOUN
mkg-56898	184	2	sodium	sodium	NOUN
mkg-56898	184	3	is	be	AUX
mkg-56898	184	4	mainly	mainly	ADV
mkg-56898	184	5	related	relate	VERB
mkg-56898	184	6	to	to	ADP
mkg-56898	184	7	synaptic	synaptic	ADJ
mkg-56898	184	8	transmission	transmission	NOUN
mkg-56898	184	9	,	,	PUNCT
mkg-56898	184	10	dopaminergic	dopaminergic	ADJ
mkg-56898	184	11	,	,	PUNCT
mkg-56898	184	12	and	and	CCONJ
mkg-56898	184	13	oxidoreductase	oxidoreductase	ADJ
mkg-56898	184	14	activity	activity	NOUN
mkg-56898	184	15	.	.	PUNCT
mkg-56898	185	1	both	both	CCONJ
mkg-56898	185	2	the	the	DET
mkg-56898	185	3	kegg	kegg	NOUN
mkg-56898	185	4	enrichment	enrichment	NOUN
mkg-56898	185	5	and	and	CCONJ
mkg-56898	185	6	gene	gene	NOUN
mkg-56898	185	7	target	target	NOUN
mkg-56898	185	8	analyses	analysis	NOUN
mkg-56898	185	9	in	in	ADP
mkg-56898	185	10	this	this	DET
mkg-56898	185	11	study	study	NOUN
mkg-56898	185	12	showed	show	VERB
mkg-56898	185	13	diclofenac	diclofenac	ADJ
mkg-56898	185	14	sodium	sodium	NOUN
mkg-56898	185	15	’s	’s	PART
mkg-56898	185	16	relation	relation	NOUN
mkg-56898	185	17	with	with	ADP
mkg-56898	185	18	dopamine	dopamine	NOUN
mkg-56898	185	19	.	.	PUNCT
mkg-56898	186	1	as	as	SCONJ
mkg-56898	186	2	dopaminergic	dopaminergic	ADJ
mkg-56898	186	3	has	have	AUX
mkg-56898	186	4	been	be	AUX
mkg-56898	186	5	reported	report	VERB
mkg-56898	186	6	to	to	PART
mkg-56898	186	7	influence	influence	VERB
mkg-56898	186	8	the	the	DET
mkg-56898	186	9	analgesic	analgesic	ADJ
mkg-56898	186	10	effect	effect	NOUN
mkg-56898	186	11	of	of	ADP
mkg-56898	186	12	paracetamol,34	paracetamol,34	NOUN
mkg-56898	186	13	diclofenac	diclofenac	NOUN
mkg-56898	186	14	sodium	sodium	NOUN
mkg-56898	186	15	has	have	VERB
mkg-56898	186	16	the	the	DET
mkg-56898	186	17	potential	potential	NOUN
mkg-56898	186	18	to	to	PART
mkg-56898	186	19	similarly	similarly	ADV
mkg-56898	186	20	act	act	VERB
mkg-56898	186	21	as	as	ADP
mkg-56898	186	22	an	an	DET
mkg-56898	186	23	analgesic	analgesic	NOUN
mkg-56898	186	24	through	through	ADP
mkg-56898	186	25	the	the	DET
mkg-56898	186	26	dopaminergic	dopaminergic	ADJ
mkg-56898	186	27	pathway	pathway	NOUN
mkg-56898	186	28	.	.	PUNCT
mkg-56898	187	1	in	in	ADP
mkg-56898	187	2	contrast	contrast	NOUN
mkg-56898	187	3	,	,	PUNCT
mkg-56898	187	4	kegg	kegg	NOUN
mkg-56898	187	5	enrichment	enrichment	NOUN
mkg-56898	187	6	analysis	analysis	NOUN
mkg-56898	187	7	failed	fail	VERB
mkg-56898	187	8	to	to	PART
mkg-56898	187	9	show	show	VERB
mkg-56898	187	10	the	the	DET
mkg-56898	187	11	relationship	relationship	NOUN
mkg-56898	187	12	of	of	ADP
mkg-56898	187	13	curcumin	curcumin	NOUN
mkg-56898	187	14	and	and	CCONJ
mkg-56898	187	15	pgv-0	pgv-0	PUNCT
mkg-56898	187	16	with	with	ADP
mkg-56898	187	17	the	the	DET
mkg-56898	187	18	dopaminergic	dopaminergic	ADJ
mkg-56898	187	19	pathway	pathway	NOUN
mkg-56898	187	20	.	.	PUNCT
mkg-56898	188	1	studies	study	NOUN
mkg-56898	188	2	demonstrate	demonstrate	VERB
mkg-56898	188	3	that	that	SCONJ
mkg-56898	188	4	curcumin	curcumin	NOUN
mkg-56898	188	5	can	can	AUX
mkg-56898	188	6	downregulate	downregulate	VERB
mkg-56898	188	7	matrix	matrix	NOUN
mkg-56898	188	8	mmps	mmp	NOUN
mkg-56898	188	9	,	,	PUNCT
mkg-56898	188	10	especially	especially	ADV
mkg-56898	188	11	mmp-13	mmp-13	PROPN
mkg-56898	188	12	,	,	PUNCT
mkg-56898	188	13	which	which	PRON
mkg-56898	188	14	plays	play	VERB
mkg-56898	188	15	a	a	DET
mkg-56898	188	16	pivotal	pivotal	ADJ
mkg-56898	188	17	role	role	NOUN
mkg-56898	188	18	in	in	ADP
mkg-56898	188	19	cartilage	cartilage	NOUN
mkg-56898	188	20	degradation.29,30	degradation.29,30	NOUN
mkg-56898	188	21	an	an	DET
mkg-56898	188	22	in	in	ADP
mkg-56898	188	23	vitro	vitro	X
mkg-56898	188	24	study	study	NOUN
mkg-56898	188	25	revealed	reveal	VERB
mkg-56898	188	26	that	that	SCONJ
mkg-56898	188	27	curcumin	curcumin	NOUN
mkg-56898	188	28	inhibits	inhibit	VERB
mkg-56898	188	29	il-1β	il-1β	PROPN
mkg-56898	188	30	-	-	PUNCT
mkg-56898	188	31	induced	induce	VERB
mkg-56898	188	32	mmp-13	mmp-13	NOUN
mkg-56898	188	33	production	production	NOUN
mkg-56898	188	34	in	in	ADP
mkg-56898	188	35	chondrocytes	chondrocyte	NOUN
mkg-56898	188	36	by	by	ADP
mkg-56898	188	37	suppressing	suppress	VERB
mkg-56898	188	38	the	the	DET
mkg-56898	188	39	phosphorylation	phosphorylation	NOUN
mkg-56898	188	40	of	of	ADP
mkg-56898	188	41	p38	p38	NOUN
mkg-56898	188	42	and	and	CCONJ
mkg-56898	188	43	jnk	jnk	PROPN
mkg-56898	188	44	-	-	PUNCT
mkg-56898	188	45	mapk	mapk	NOUN
mkg-56898	188	46	signaling	signal	VERB
mkg-56898	188	47	pathways.35	pathways.35	NOUN
mkg-56898	188	48	in	in	ADP
mkg-56898	188	49	conclusion	conclusion	NOUN
mkg-56898	188	50	,	,	PUNCT
mkg-56898	188	51	this	this	DET
mkg-56898	188	52	bioinformatic	bioinformatic	ADJ
mkg-56898	188	53	study	study	NOUN
mkg-56898	188	54	showed	show	VERB
mkg-56898	188	55	that	that	SCONJ
mkg-56898	188	56	,	,	PUNCT
mkg-56898	188	57	as	as	ADP
mkg-56898	188	58	an	an	DET
mkg-56898	188	59	analog	analog	NOUN
mkg-56898	188	60	of	of	ADP
mkg-56898	188	61	curcumin	curcumin	NOUN
mkg-56898	188	62	,	,	PUNCT
mkg-56898	188	63	pgv-0	pgv-0	PUNCT
mkg-56898	188	64	targeted	target	VERB
mkg-56898	188	65	mmp	mmp	PROPN
mkg-56898	188	66	in	in	ADP
mkg-56898	188	67	temporomandibular	temporomandibular	ADJ
mkg-56898	188	68	arthritis	arthritis	NOUN
mkg-56898	188	69	pathogenesis	pathogenesis	NOUN
mkg-56898	188	70	.	.	PUNCT
mkg-56898	189	1	this	this	DET
mkg-56898	189	2	finding	finding	NOUN
mkg-56898	189	3	underlined	underline	VERB
mkg-56898	189	4	the	the	DET
mkg-56898	189	5	advantage	advantage	NOUN
mkg-56898	189	6	of	of	ADP
mkg-56898	189	7	pgv-0	pgv-0	PUNCT
mkg-56898	189	8	in	in	ADP
mkg-56898	189	9	preventing	prevent	VERB
mkg-56898	189	10	mmprelated	mmprelated	ADJ
mkg-56898	189	11	tissue	tissue	NOUN
mkg-56898	189	12	damage	damage	NOUN
mkg-56898	189	13	in	in	ADP
mkg-56898	189	14	temporomandibular	temporomandibular	ADJ
mkg-56898	189	15	arthritis	arthritis	NOUN
mkg-56898	189	16	.	.	PUNCT
mkg-56898	190	1	acknowledgement	acknowledgement	NOUN
mkg-56898	190	2	through	through	ADP
mkg-56898	190	3	the	the	DET
mkg-56898	190	4	program	program	NOUN
mkg-56898	190	5	of	of	ADP
mkg-56898	190	6	rekognisi	rekognisi	ADJ
mkg-56898	190	7	tugas	tugas	PROPN
mkg-56898	190	8	akhir	akhir	PROPN
mkg-56898	190	9	(	(	PUNCT
mkg-56898	190	10	number	number	NOUN
mkg-56898	190	11	3143	3143	NUM
mkg-56898	190	12	/	/	SYM
mkg-56898	190	13	un1.p.iii	un1.p.iii	SYM
mkg-56898	190	14	/	/	SYM
mkg-56898	190	15	dit	dit	ADJ
mkg-56898	190	16	-	-	PUNCT
mkg-56898	190	17	lit	light	VERB
mkg-56898	190	18	/	/	SYM
mkg-56898	190	19	pt/2021	pt/2021	NOUN
mkg-56898	190	20	)	)	PUNCT
mkg-56898	190	21	,	,	PUNCT
mkg-56898	190	22	we	we	PRON
mkg-56898	190	23	express	express	VERB
mkg-56898	190	24	our	our	PRON
mkg-56898	190	25	gratitude	gratitude	NOUN
mkg-56898	190	26	to	to	AUX
mkg-56898	190	27	universitas	universita	NOUN
mkg-56898	190	28	gadjah	gadjah	PROPN
mkg-56898	190	29	mada	mada	PROPN
mkg-56898	190	30	for	for	ADP
mkg-56898	190	31	its	its	PRON
mkg-56898	190	32	financial	financial	ADJ
mkg-56898	190	33	support	support	NOUN
mkg-56898	190	34	.	.	PUNCT
mkg-56898	191	1	copyright	copyright	NOUN
mkg-56898	191	2	©	©	PROPN
mkg-56898	191	3	2025	2025	NUM
mkg-56898	191	4	dental	dental	ADJ
mkg-56898	191	5	journal	journal	NOUN
mkg-56898	191	6	(	(	PUNCT
mkg-56898	191	7	majalah	majalah	PROPN
mkg-56898	191	8	kedokteran	kedokteran	PROPN
mkg-56898	191	9	gigi	gigi	PROPN
mkg-56898	191	10	)	)	PUNCT
mkg-56898	192	1	p	p	X
mkg-56898	192	2	-	-	PUNCT
mkg-56898	192	3	issn	issn	NOUN
mkg-56898	192	4	:	:	PUNCT
mkg-56898	192	5	1978	1978	NUM
mkg-56898	192	6	-	-	SYM
mkg-56898	192	7	3728	3728	NUM
mkg-56898	192	8	;	;	PUNCT
mkg-56898	192	9	e	e	X
mkg-56898	192	10	-	-	PUNCT
mkg-56898	192	11	issn	issn	ADJ
mkg-56898	192	12	:	:	PUNCT
mkg-56898	192	13	2442	2442	NUM
mkg-56898	192	14	-	-	SYM
mkg-56898	192	15	9740	9740	NUM
mkg-56898	192	16	.	.	PUNCT
mkg-56898	193	1	accredited	accredit	VERB
mkg-56898	193	2	no	no	INTJ
mkg-56898	193	3	.	.	PROPN
mkg-56898	194	1	158	158	NUM
mkg-56898	194	2	/	/	SYM
mkg-56898	194	3	e	e	NOUN
mkg-56898	194	4	/	/	SYM
mkg-56898	194	5	kpt/2021	kpt/2021	NOUN
mkg-56898	194	6	.	.	PUNCT
mkg-56898	195	1	open	open	ADJ
mkg-56898	195	2	access	access	NOUN
mkg-56898	195	3	under	under	ADP
mkg-56898	195	4	cc	cc	NOUN
mkg-56898	195	5	-	-	PUNCT
mkg-56898	195	6	by	by	ADP
mkg-56898	195	7	-	-	PUNCT
mkg-56898	195	8	sa	sa	NOUN
mkg-56898	195	9	license	license	NOUN
mkg-56898	195	10	.	.	PUNCT
mkg-56898	196	1	available	available	ADJ
mkg-56898	196	2	at	at	ADP
mkg-56898	196	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	196	4	doi	doi	NOUN
mkg-56898	196	5	:	:	PUNCT
mkg-56898	197	1	10.20473	10.20473	NUM
mkg-56898	197	2	/	/	SYM
mkg-56898	197	3	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	PROPN
mkg-56898	197	4	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	197	5	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	NOUN
mkg-56898	197	6	375robin	375robin	PROPN
mkg-56898	197	7	et	et	PROPN
mkg-56898	197	8	al	al	PROPN
mkg-56898	197	9	.	.	PROPN
mkg-56898	197	10	dent	dent	PROPN
mkg-56898	197	11	.	.	PUNCT
mkg-56898	198	1	j.	j.	PROPN
mkg-56898	198	2	(	(	PUNCT
mkg-56898	198	3	majalah	majalah	PROPN
mkg-56898	198	4	kedokteran	kedokteran	PROPN
mkg-56898	198	5	gigi	gigi	PROPN
mkg-56898	198	6	)	)	PUNCT
mkg-56898	198	7	2025	2025	NUM
mkg-56898	198	8	december	december	NOUN
mkg-56898	198	9	;	;	PUNCT
mkg-56898	198	10	58(4	58(4	NUM
mkg-56898	198	11	):	):	PUNCT
mkg-56898	198	12	367–375	367–375	NUM
mkg-56898	198	13	references	reference	NOUN
mkg-56898	198	14	1	1	NUM
mkg-56898	198	15	.	.	PUNCT
mkg-56898	198	16	valesan	valesan	ADJ
mkg-56898	198	17	lf	lf	PROPN
mkg-56898	198	18	,	,	PUNCT
mkg-56898	198	19	da	da	PROPN
mkg-56898	198	20	-	-	PUNCT
mkg-56898	198	21	cas	cas	PROPN
mkg-56898	198	22	cd	cd	PROPN
mkg-56898	198	23	,	,	PUNCT
mkg-56898	198	24	réus	réus	PROPN
mkg-56898	198	25	jc	jc	PROPN
mkg-56898	198	26	,	,	PUNCT
mkg-56898	198	27	denardin	denardin	NOUN
mkg-56898	198	28	acs	acs	PROPN
mkg-56898	198	29	,	,	PUNCT
mkg-56898	198	30	garanhani	garanhani	PROPN
mkg-56898	198	31	rr	rr	PROPN
mkg-56898	198	32	,	,	PUNCT
mkg-56898	198	33	bonotto	bonotto	PROPN
mkg-56898	198	34	d	d	PROPN
mkg-56898	198	35	,	,	PUNCT
mkg-56898	198	36	januzzi	januzzi	PROPN
mkg-56898	198	37	e	e	NOUN
mkg-56898	198	38	,	,	PUNCT
mkg-56898	198	39	de	de	PROPN
mkg-56898	198	40	souza	souza	PROPN
mkg-56898	198	41	bdm	bdm	NOUN
mkg-56898	198	42	.	.	PUNCT
mkg-56898	199	1	prevalence	prevalence	NOUN
mkg-56898	199	2	of	of	ADP
mkg-56898	199	3	temporomandibular	temporomandibular	ADJ
mkg-56898	199	4	joint	joint	ADJ
mkg-56898	199	5	disorders	disorder	NOUN
mkg-56898	199	6	:	:	PUNCT
mkg-56898	199	7	a	a	DET
mkg-56898	199	8	systematic	systematic	ADJ
mkg-56898	199	9	review	review	NOUN
mkg-56898	199	10	and	and	CCONJ
mkg-56898	199	11	metaanalysis	metaanalysis	NOUN
mkg-56898	199	12	.	.	PUNCT
mkg-56898	200	1	clin	clin	PROPN
mkg-56898	200	2	oral	oral	PROPN
mkg-56898	200	3	investig	investig	PROPN
mkg-56898	200	4	.	.	PROPN
mkg-56898	200	5	2021	2021	NUM
mkg-56898	200	6	;	;	PUNCT
mkg-56898	200	7	25(2	25(2	NUM
mkg-56898	200	8	):	):	PUNCT
mkg-56898	200	9	441–53	441–53	NUM
mkg-56898	200	10	.	.	PUNCT
mkg-56898	201	1	2	2	NUM
mkg-56898	201	2	.	.	X
mkg-56898	201	3	marpaung	marpaung	PROPN
mkg-56898	201	4	c	c	PROPN
mkg-56898	201	5	,	,	PUNCT
mkg-56898	201	6	van	van	PROPN
mkg-56898	201	7	selms	selms	PROPN
mkg-56898	201	8	mka	mka	PROPN
mkg-56898	201	9	,	,	PUNCT
mkg-56898	201	10	lobbezoo	lobbezoo	PROPN
mkg-56898	201	11	f.	f.	PROPN
mkg-56898	201	12	prevalence	prevalence	PROPN
mkg-56898	201	13	and	and	CCONJ
mkg-56898	201	14	risk	risk	NOUN
mkg-56898	201	15	indicators	indicator	NOUN
mkg-56898	201	16	of	of	ADP
mkg-56898	201	17	pain	pain	NOUN
mkg-56898	201	18	-	-	PUNCT
mkg-56898	201	19	related	relate	VERB
mkg-56898	201	20	temporomandibular	temporomandibular	ADJ
mkg-56898	201	21	disorders	disorder	NOUN
mkg-56898	201	22	among	among	ADP
mkg-56898	201	23	indonesian	indonesian	ADJ
mkg-56898	201	24	children	child	NOUN
mkg-56898	201	25	and	and	CCONJ
mkg-56898	201	26	adolescents	adolescent	NOUN
mkg-56898	201	27	.	.	PUNCT
mkg-56898	202	1	community	community	NOUN
mkg-56898	202	2	dent	dent	NOUN
mkg-56898	202	3	oral	oral	ADJ
mkg-56898	202	4	epidemiol	epidemiol	NOUN
mkg-56898	202	5	.	.	PUNCT
mkg-56898	202	6	2018	2018	NUM
mkg-56898	202	7	;	;	PUNCT
mkg-56898	202	8	46(4	46(4	NUM
mkg-56898	202	9	):	):	PUNCT
mkg-56898	202	10	400–6	400–6	PROPN
mkg-56898	202	11	.	.	PROPN
mkg-56898	203	1	3	3	X
mkg-56898	203	2	.	.	X
mkg-56898	203	3	almeida	almeida	PROPN
mkg-56898	203	4	le	le	PROPN
mkg-56898	203	5	,	,	PUNCT
mkg-56898	203	6	doetzer	doetzer	NOUN
mkg-56898	203	7	a	a	PRON
mkg-56898	203	8	,	,	PUNCT
mkg-56898	203	9	beck	beck	PROPN
mkg-56898	203	10	ml	ml	PROPN
mkg-56898	203	11	.	.	PUNCT
mkg-56898	204	1	immunohistochemical	immunohistochemical	ADJ
mkg-56898	204	2	markers	marker	NOUN
mkg-56898	204	3	of	of	ADP
mkg-56898	204	4	temporomandibular	temporomandibular	ADJ
mkg-56898	204	5	disorders	disorder	NOUN
mkg-56898	204	6	:	:	PUNCT
mkg-56898	204	7	a	a	DET
mkg-56898	204	8	review	review	NOUN
mkg-56898	204	9	of	of	ADP
mkg-56898	204	10	the	the	DET
mkg-56898	204	11	literature	literature	NOUN
mkg-56898	204	12	.	.	PUNCT
mkg-56898	205	1	j	j	PROPN
mkg-56898	205	2	clin	clin	PROPN
mkg-56898	205	3	med	med	PROPN
mkg-56898	205	4	.	.	PUNCT
mkg-56898	205	5	2023	2023	NUM
mkg-56898	205	6	;	;	PUNCT
mkg-56898	205	7	12(3	12(3	NUM
mkg-56898	205	8	):	):	PUNCT
mkg-56898	205	9	789	789	NUM
mkg-56898	205	10	.	.	X
mkg-56898	205	11	4	4	NUM
mkg-56898	205	12	.	.	X
mkg-56898	205	13	monasterio	monasterio	PROPN
mkg-56898	205	14	g	g	PROPN
mkg-56898	205	15	,	,	PUNCT
mkg-56898	205	16	castillo	castillo	PROPN
mkg-56898	205	17	f	f	PROPN
mkg-56898	205	18	,	,	PUNCT
mkg-56898	205	19	betancur	betancur	VERB
mkg-56898	205	20	d	d	PROPN
mkg-56898	205	21	,	,	PUNCT
mkg-56898	205	22	hernández	hernández	PROPN
mkg-56898	205	23	a	a	X
mkg-56898	205	24	,	,	PUNCT
mkg-56898	205	25	flores	flore	VERB
mkg-56898	205	26	g	g	PROPN
mkg-56898	205	27	,	,	PUNCT
mkg-56898	205	28	díaz	díaz	PROPN
mkg-56898	205	29	w	w	PROPN
mkg-56898	205	30	,	,	PUNCT
mkg-56898	205	31	hernández	hernández	PROPN
mkg-56898	205	32	m	m	PROPN
mkg-56898	205	33	,	,	PUNCT
mkg-56898	205	34	vernal	vernal	PROPN
mkg-56898	205	35	r.	r.	PROPN
mkg-56898	205	36	osteoarthritis	osteoarthritis	PROPN
mkg-56898	205	37	of	of	ADP
mkg-56898	205	38	the	the	DET
mkg-56898	205	39	temporomandibular	temporomandibular	ADJ
mkg-56898	205	40	joint	joint	NOUN
mkg-56898	205	41	:	:	PUNCT
mkg-56898	205	42	clinical	clinical	ADJ
mkg-56898	205	43	and	and	CCONJ
mkg-56898	205	44	imagenological	imagenological	ADJ
mkg-56898	205	45	diagnosis	diagnosis	NOUN
mkg-56898	205	46	,	,	PUNCT
mkg-56898	205	47	pathogenic	pathogenic	ADJ
mkg-56898	205	48	role	role	NOUN
mkg-56898	205	49	of	of	ADP
mkg-56898	205	50	the	the	DET
mkg-56898	205	51	immunoinflammatory	immunoinflammatory	ADJ
mkg-56898	205	52	response	response	NOUN
mkg-56898	205	53	,	,	PUNCT
mkg-56898	205	54	and	and	CCONJ
mkg-56898	205	55	immunotherapeutic	immunotherapeutic	ADJ
mkg-56898	205	56	strategies	strategy	NOUN
mkg-56898	205	57	based	base	VERB
mkg-56898	205	58	on	on	ADP
mkg-56898	205	59	t	t	PROPN
mkg-56898	205	60	regulatory	regulatory	ADJ
mkg-56898	205	61	lymphocytes	lymphocyte	NOUN
mkg-56898	205	62	.	.	PUNCT
mkg-56898	206	1	in	in	ADP
mkg-56898	206	2	:	:	PUNCT
mkg-56898	206	3	temporomandibular	temporomandibular	ADJ
mkg-56898	206	4	joint	joint	ADJ
mkg-56898	206	5	pathology	pathology	NOUN
mkg-56898	206	6	current	current	ADJ
mkg-56898	206	7	approaches	approach	NOUN
mkg-56898	206	8	and	and	CCONJ
mkg-56898	206	9	understanding	understanding	NOUN
mkg-56898	206	10	.	.	PUNCT
mkg-56898	207	1	intech	intech	PROPN
mkg-56898	207	2	;	;	PUNCT
mkg-56898	207	3	2018	2018	NUM
mkg-56898	207	4	.	.	PUNCT
mkg-56898	208	1	p.	p.	NOUN
mkg-56898	208	2	208	208	NUM
mkg-56898	208	3	.	.	PUNCT
mkg-56898	209	1	5	5	X
mkg-56898	209	2	.	.	X
mkg-56898	209	3	lu	lu	PROPN
mkg-56898	210	1	k	k	PROPN
mkg-56898	210	2	,	,	PUNCT
mkg-56898	210	3	ma	ma	PROPN
mkg-56898	210	4	f	f	PROPN
mkg-56898	210	5	,	,	PUNCT
mkg-56898	210	6	yi	yi	PROPN
mkg-56898	210	7	d	d	PROPN
mkg-56898	210	8	,	,	PUNCT
mkg-56898	210	9	yu	yu	PROPN
mkg-56898	210	10	h	h	NOUN
mkg-56898	210	11	,	,	PUNCT
mkg-56898	210	12	tong	tong	PROPN
mkg-56898	210	13	l	l	PROPN
mkg-56898	210	14	,	,	PUNCT
mkg-56898	210	15	chen	chen	PROPN
mkg-56898	210	16	d.	d.	PROPN
mkg-56898	210	17	molecular	molecular	PROPN
mkg-56898	210	18	signaling	signal	VERB
mkg-56898	210	19	in	in	ADP
mkg-56898	210	20	temporomandibular	temporomandibular	ADJ
mkg-56898	210	21	joint	joint	ADJ
mkg-56898	210	22	osteoarthritis	osteoarthritis	NOUN
mkg-56898	210	23	.	.	PUNCT
mkg-56898	211	1	j	j	PROPN
mkg-56898	211	2	orthop	orthop	PROPN
mkg-56898	211	3	transl	transl	PROPN
mkg-56898	211	4	.	.	PUNCT
mkg-56898	212	1	2022	2022	NUM
mkg-56898	212	2	;	;	PUNCT
mkg-56898	212	3	32	32	NUM
mkg-56898	212	4	:	:	PUNCT
mkg-56898	213	1	21–7	21–7	NUM
mkg-56898	213	2	.	.	NOUN
mkg-56898	214	1	6	6	NUM
mkg-56898	214	2	.	.	X
mkg-56898	214	3	wang	wang	PROPN
mkg-56898	214	4	xd	xd	PROPN
mkg-56898	214	5	,	,	PUNCT
mkg-56898	214	6	zhang	zhang	PROPN
mkg-56898	214	7	jn	jn	PROPN
mkg-56898	214	8	,	,	PUNCT
mkg-56898	214	9	gan	gan	PROPN
mkg-56898	214	10	yh	yh	PROPN
mkg-56898	214	11	,	,	PUNCT
mkg-56898	214	12	zhou	zhou	PROPN
mkg-56898	214	13	yh	yh	PROPN
mkg-56898	214	14	.	.	PUNCT
mkg-56898	214	15	current	current	ADJ
mkg-56898	214	16	understanding	understanding	NOUN
mkg-56898	214	17	of	of	ADP
mkg-56898	214	18	pathogenesis	pathogenesis	NOUN
mkg-56898	214	19	and	and	CCONJ
mkg-56898	214	20	treatment	treatment	NOUN
mkg-56898	214	21	of	of	ADP
mkg-56898	214	22	tmj	tmj	PROPN
mkg-56898	214	23	osteoarthritis	osteoarthritis	PROPN
mkg-56898	214	24	.	.	PUNCT
mkg-56898	215	1	j	j	PROPN
mkg-56898	215	2	dent	dent	NOUN
mkg-56898	215	3	res	re	NOUN
mkg-56898	215	4	.	.	PUNCT
mkg-56898	215	5	2015	2015	NUM
mkg-56898	215	6	;	;	PUNCT
mkg-56898	215	7	94(5	94(5	NUM
mkg-56898	215	8	):	):	PUNCT
mkg-56898	215	9	666–73	666–73	NOUN
mkg-56898	215	10	.	.	PUNCT
mkg-56898	216	1	7	7	X
mkg-56898	216	2	.	.	X
mkg-56898	217	1	ouanounou	ouanounou	NOUN
mkg-56898	217	2	a	a	PROPN
mkg-56898	217	3	,	,	PUNCT
mkg-56898	217	4	goldberg	goldberg	PROPN
mkg-56898	217	5	m	m	PROPN
mkg-56898	217	6	,	,	PUNCT
mkg-56898	217	7	haas	haas	PROPN
mkg-56898	217	8	da	da	PROPN
mkg-56898	217	9	.	.	PUNCT
mkg-56898	218	1	pharmacotherapy	pharmacotherapy	NOUN
mkg-56898	218	2	in	in	ADP
mkg-56898	218	3	temporomandibular	temporomandibular	ADJ
mkg-56898	218	4	disorders	disorder	NOUN
mkg-56898	218	5	:	:	PUNCT
mkg-56898	218	6	a	a	DET
mkg-56898	218	7	review	review	NOUN
mkg-56898	218	8	.	.	PUNCT
mkg-56898	219	1	j	j	PROPN
mkg-56898	219	2	can	can	AUX
mkg-56898	219	3	dent	dent	VERB
mkg-56898	219	4	assoc	assoc	NOUN
mkg-56898	219	5	.	.	PUNCT
mkg-56898	220	1	2017	2017	NUM
mkg-56898	220	2	;	;	PUNCT
mkg-56898	220	3	83	83	NUM
mkg-56898	220	4	:	:	PUNCT
mkg-56898	220	5	h7	h7	PROPN
mkg-56898	220	6	.	.	PUNCT
mkg-56898	221	1	8	8	NUM
mkg-56898	221	2	.	.	X
mkg-56898	221	3	kołodziejska	kołodziejska	PROPN
mkg-56898	221	4	j	j	PROPN
mkg-56898	221	5	,	,	PUNCT
mkg-56898	221	6	kołodziejczyk	kołodziejczyk	PROPN
mkg-56898	221	7	m.	m.	NOUN
mkg-56898	221	8	diclofenac	diclofenac	NOUN
mkg-56898	221	9	in	in	ADP
mkg-56898	221	10	the	the	DET
mkg-56898	221	11	treatment	treatment	NOUN
mkg-56898	221	12	of	of	ADP
mkg-56898	221	13	pain	pain	NOUN
mkg-56898	221	14	in	in	ADP
mkg-56898	221	15	patients	patient	NOUN
mkg-56898	221	16	with	with	ADP
mkg-56898	221	17	rheumatic	rheumatic	ADJ
mkg-56898	221	18	diseases	disease	NOUN
mkg-56898	221	19	.	.	PUNCT
mkg-56898	222	1	reumatologia	reumatologia	ADJ
mkg-56898	222	2	.	.	PUNCT
mkg-56898	223	1	2018	2018	NUM
mkg-56898	223	2	;	;	PUNCT
mkg-56898	223	3	56(3	56(3	NUM
mkg-56898	223	4	):	):	PUNCT
mkg-56898	223	5	174–83	174–83	NOUN
mkg-56898	223	6	.	.	PUNCT
mkg-56898	224	1	9	9	NUM
mkg-56898	224	2	.	.	X
mkg-56898	224	3	bindu	bindu	PROPN
mkg-56898	224	4	s	s	PROPN
mkg-56898	224	5	,	,	PUNCT
mkg-56898	224	6	mazumder	mazumder	NOUN
mkg-56898	224	7	s	s	PROPN
mkg-56898	224	8	,	,	PUNCT
mkg-56898	224	9	bandyopadhyay	bandyopadhyay	PROPN
mkg-56898	224	10	u.	u.	PROPN
mkg-56898	224	11	non	non	PROPN
mkg-56898	224	12	-	-	ADJ
mkg-56898	224	13	steroidal	steroidal	ADJ
mkg-56898	224	14	antiinflammatory	antiinflammatory	NOUN
mkg-56898	224	15	drugs	drug	NOUN
mkg-56898	224	16	(	(	PUNCT
mkg-56898	224	17	nsaids	nsaids	PROPN
mkg-56898	224	18	)	)	PUNCT
mkg-56898	224	19	and	and	CCONJ
mkg-56898	224	20	organ	organ	NOUN
mkg-56898	224	21	damage	damage	NOUN
mkg-56898	224	22	:	:	PUNCT
mkg-56898	224	23	a	a	DET
mkg-56898	224	24	current	current	ADJ
mkg-56898	224	25	perspective	perspective	NOUN
mkg-56898	224	26	.	.	PUNCT
mkg-56898	225	1	biochem	biochem	PROPN
mkg-56898	225	2	pharmacol	pharmacol	PROPN
mkg-56898	225	3	.	.	PUNCT
mkg-56898	226	1	2020	2020	NUM
mkg-56898	226	2	;	;	PUNCT
mkg-56898	226	3	180	180	NUM
mkg-56898	226	4	:	:	SYM
mkg-56898	226	5	114147	114147	NUM
mkg-56898	226	6	.	.	PUNCT
mkg-56898	227	1	10	10	NUM
mkg-56898	227	2	.	.	X
mkg-56898	228	1	boarescu	boarescu	PROPN
mkg-56898	228	2	i	i	PROPN
mkg-56898	228	3	,	,	PUNCT
mkg-56898	228	4	pop	pop	PROPN
mkg-56898	228	5	rm	rm	PROPN
mkg-56898	228	6	,	,	PUNCT
mkg-56898	228	7	boarescu	boarescu	NOUN
mkg-56898	228	8	p	p	PROPN
mkg-56898	228	9	-	-	PUNCT
mkg-56898	228	10	m	m	PROPN
mkg-56898	228	11	,	,	PUNCT
mkg-56898	228	12	bocșan	bocșan	VERB
mkg-56898	228	13	ic	ic	PROPN
mkg-56898	228	14	,	,	PUNCT
mkg-56898	228	15	gheban	gheban	NOUN
mkg-56898	228	16	d	d	PROPN
mkg-56898	228	17	,	,	PUNCT
mkg-56898	228	18	râjnoveanu	râjnoveanu	ADJ
mkg-56898	228	19	r	r	NOUN
mkg-56898	228	20	-	-	PUNCT
mkg-56898	228	21	m	m	PROPN
mkg-56898	228	22	,	,	PUNCT
mkg-56898	228	23	râjnoveanu	râjnoveanu	PROPN
mkg-56898	228	24	a	a	PRON
mkg-56898	228	25	,	,	PUNCT
mkg-56898	228	26	bulboacă	bulboacă	PROPN
mkg-56898	228	27	ae	ae	PROPN
mkg-56898	228	28	,	,	PUNCT
mkg-56898	228	29	buzoianu	buzoianu	VERB
mkg-56898	228	30	ad	ad	NOUN
mkg-56898	228	31	,	,	PUNCT
mkg-56898	228	32	bolboacă	bolboacă	VERB
mkg-56898	228	33	sd	sd	NOUN
mkg-56898	228	34	.	.	PUNCT
mkg-56898	229	1	anti	anti	ADJ
mkg-56898	229	2	-	-	ADJ
mkg-56898	229	3	inflammatory	inflammatory	ADJ
mkg-56898	229	4	and	and	CCONJ
mkg-56898	229	5	analgesic	analgesic	ADJ
mkg-56898	229	6	effects	effect	NOUN
mkg-56898	229	7	of	of	ADP
mkg-56898	229	8	curcumin	curcumin	NOUN
mkg-56898	229	9	nanoparticles	nanoparticle	NOUN
mkg-56898	229	10	associated	associate	VERB
mkg-56898	229	11	with	with	ADP
mkg-56898	229	12	diclofenac	diclofenac	ADJ
mkg-56898	229	13	sodium	sodium	NOUN
mkg-56898	229	14	in	in	ADP
mkg-56898	229	15	experimental	experimental	ADJ
mkg-56898	229	16	acute	acute	ADJ
mkg-56898	229	17	inflammation	inflammation	NOUN
mkg-56898	229	18	.	.	PUNCT
mkg-56898	230	1	int	int	PROPN
mkg-56898	230	2	j	j	PROPN
mkg-56898	230	3	mol	mol	ADP
mkg-56898	230	4	sci	sci	PROPN
mkg-56898	230	5	.	.	PROPN
mkg-56898	230	6	2022	2022	NUM
mkg-56898	230	7	;	;	PUNCT
mkg-56898	230	8	23(19	23(19	NUM
mkg-56898	230	9	):	):	PUNCT
mkg-56898	230	10	11737	11737	NUM
mkg-56898	230	11	.	.	PUNCT
mkg-56898	231	1	11	11	NUM
mkg-56898	231	2	.	.	PUNCT
mkg-56898	232	1	busse	busse	PROPN
mkg-56898	232	2	jw	jw	PROPN
mkg-56898	232	3	,	,	PUNCT
mkg-56898	232	4	casassus	casassus	ADJ
mkg-56898	232	5	r	r	PROPN
mkg-56898	232	6	,	,	PUNCT
mkg-56898	232	7	carrasco	carrasco	PROPN
mkg-56898	232	8	-	-	PUNCT
mkg-56898	232	9	labra	labra	PROPN
mkg-56898	232	10	a	a	PRON
mkg-56898	232	11	,	,	PUNCT
mkg-56898	232	12	durham	durham	PROPN
mkg-56898	232	13	j	j	PROPN
mkg-56898	232	14	,	,	PUNCT
mkg-56898	232	15	mock	mock	ADJ
mkg-56898	232	16	d	d	NOUN
mkg-56898	232	17	,	,	PUNCT
mkg-56898	232	18	zakrzewska	zakrzewska	PROPN
mkg-56898	232	19	jm	jm	PROPN
mkg-56898	232	20	,	,	PUNCT
mkg-56898	232	21	palmer	palmer	PROPN
mkg-56898	232	22	c	c	PROPN
mkg-56898	232	23	,	,	PUNCT
mkg-56898	232	24	samer	samer	PROPN
mkg-56898	232	25	cf	cf	PROPN
mkg-56898	232	26	,	,	PUNCT
mkg-56898	232	27	coen	coen	PROPN
mkg-56898	232	28	m	m	PROPN
mkg-56898	232	29	,	,	PUNCT
mkg-56898	232	30	guevremont	guevremont	PROPN
mkg-56898	232	31	b	b	PROPN
mkg-56898	232	32	,	,	PUNCT
mkg-56898	232	33	hoppe	hoppe	PROPN
mkg-56898	232	34	t	t	PROPN
mkg-56898	232	35	,	,	PUNCT
mkg-56898	232	36	guyatt	guyatt	PROPN
mkg-56898	232	37	gh	gh	PROPN
mkg-56898	232	38	,	,	PUNCT
mkg-56898	232	39	crandon	crandon	PROPN
mkg-56898	232	40	hn	hn	PROPN
mkg-56898	232	41	,	,	PUNCT
mkg-56898	232	42	yao	yao	PROPN
mkg-56898	232	43	l	l	PROPN
mkg-56898	232	44	,	,	PUNCT
mkg-56898	232	45	sadeghirad	sadeghirad	PROPN
mkg-56898	232	46	b	b	PROPN
mkg-56898	232	47	,	,	PUNCT
mkg-56898	232	48	vandvik	vandvik	ADV
mkg-56898	232	49	po	po	NOUN
mkg-56898	232	50	,	,	PUNCT
mkg-56898	232	51	siemieniuk	siemieniuk	PROPN
mkg-56898	232	52	rac	rac	PROPN
mkg-56898	232	53	,	,	PUNCT
mkg-56898	232	54	lytvyn	lytvyn	PROPN
mkg-56898	232	55	l	l	PROPN
mkg-56898	232	56	,	,	PUNCT
mkg-56898	232	57	hunskaar	hunskaar	NOUN
mkg-56898	232	58	bs	bs	NOUN
mkg-56898	232	59	,	,	PUNCT
mkg-56898	232	60	agoritsas	agoritsa	NOUN
mkg-56898	232	61	t.	t.	NOUN
mkg-56898	232	62	management	management	NOUN
mkg-56898	232	63	of	of	ADP
mkg-56898	232	64	chronic	chronic	ADJ
mkg-56898	232	65	pain	pain	NOUN
mkg-56898	232	66	associated	associate	VERB
mkg-56898	232	67	with	with	ADP
mkg-56898	232	68	temporomandibular	temporomandibular	ADJ
mkg-56898	232	69	disorders	disorder	NOUN
mkg-56898	232	70	:	:	PUNCT
mkg-56898	232	71	a	a	DET
mkg-56898	232	72	clinical	clinical	ADJ
mkg-56898	232	73	practice	practice	NOUN
mkg-56898	232	74	guideline	guideline	NOUN
mkg-56898	232	75	.	.	PUNCT
mkg-56898	233	1	bmj	bmj	PROPN
mkg-56898	233	2	.	.	PUNCT
mkg-56898	234	1	2023	2023	NUM
mkg-56898	234	2	;	;	PUNCT
mkg-56898	234	3	383	383	NUM
mkg-56898	234	4	:	:	PUNCT
mkg-56898	234	5	e076227	e076227	PROPN
mkg-56898	234	6	.	.	PUNCT
mkg-56898	235	1	12	12	NUM
mkg-56898	235	2	.	.	PUNCT
mkg-56898	236	1	amin	amin	PROPN
mkg-56898	236	2	le	le	PROPN
mkg-56898	236	3	,	,	PUNCT
mkg-56898	236	4	gamily	gamily	ADV
mkg-56898	236	5	m	m	VERB
mkg-56898	236	6	el	el	PROPN
mkg-56898	236	7	.	.	PUNCT
mkg-56898	236	8	biological	biological	ADJ
mkg-56898	236	9	impact	impact	NOUN
mkg-56898	236	10	of	of	ADP
mkg-56898	236	11	curcumin	curcumin	NOUN
mkg-56898	236	12	on	on	ADP
mkg-56898	236	13	the	the	DET
mkg-56898	236	14	healing	healing	NOUN
mkg-56898	236	15	of	of	ADP
mkg-56898	236	16	tempromandibular	tempromandibular	NOUN
mkg-56898	236	17	joint	joint	NOUN
mkg-56898	236	18	in	in	ADP
mkg-56898	236	19	experimentally	experimentally	ADV
mkg-56898	236	20	induced	induce	VERB
mkg-56898	236	21	arthritis	arthritis	NOUN
mkg-56898	236	22	.	.	PUNCT
mkg-56898	237	1	j	j	PROPN
mkg-56898	237	2	oral	oral	ADJ
mkg-56898	237	3	maxillofac	maxillofac	NOUN
mkg-56898	237	4	surgery	surgery	NOUN
mkg-56898	237	5	,	,	PUNCT
mkg-56898	237	6	med	med	ADJ
mkg-56898	237	7	pathol	pathol	NOUN
mkg-56898	237	8	.	.	PUNCT
mkg-56898	237	9	2021	2021	NUM
mkg-56898	237	10	;	;	PUNCT
mkg-56898	237	11	33(3	33(3	NUM
mkg-56898	237	12	):	):	PUNCT
mkg-56898	237	13	260–6	260–6	NOUN
mkg-56898	237	14	.	.	PROPN
mkg-56898	237	15	13	13	NUM
mkg-56898	237	16	.	.	PUNCT
mkg-56898	238	1	phumsuay	phumsuay	PROPN
mkg-56898	238	2	r	r	PROPN
mkg-56898	238	3	,	,	PUNCT
mkg-56898	238	4	muangnoi	muangnoi	PROPN
mkg-56898	238	5	c	c	PROPN
mkg-56898	238	6	,	,	PUNCT
mkg-56898	238	7	dasuni	dasuni	PROPN
mkg-56898	238	8	wasana	wasana	PROPN
mkg-56898	238	9	pw	pw	PROPN
mkg-56898	238	10	,	,	PUNCT
mkg-56898	238	11	hasriadi	hasriadi	NOUN
mkg-56898	238	12	,	,	PUNCT
mkg-56898	238	13	vajragupta	vajragupta	NOUN
mkg-56898	238	14	o	o	NOUN
mkg-56898	238	15	,	,	PUNCT
mkg-56898	238	16	rojsitthisak	rojsitthisak	VERB
mkg-56898	238	17	p	p	NOUN
mkg-56898	238	18	,	,	PUNCT
mkg-56898	238	19	towiwat	towiwat	ADJ
mkg-56898	238	20	p.	p.	NOUN
mkg-56898	238	21	molecular	molecular	ADJ
mkg-56898	238	22	insight	insight	NOUN
mkg-56898	238	23	into	into	ADP
mkg-56898	238	24	the	the	DET
mkg-56898	238	25	antiinflammatory	antiinflammatory	NOUN
mkg-56898	238	26	effects	effect	NOUN
mkg-56898	238	27	of	of	ADP
mkg-56898	238	28	the	the	DET
mkg-56898	238	29	curcumin	curcumin	NOUN
mkg-56898	238	30	ester	ester	NOUN
mkg-56898	238	31	prodrug	prodrug	PROPN
mkg-56898	238	32	curcumin	curcumin	PROPN
mkg-56898	238	33	diglutaric	diglutaric	PROPN
mkg-56898	238	34	acid	acid	PROPN
mkg-56898	238	35	in	in	ADP
mkg-56898	238	36	vitro	vitro	X
mkg-56898	238	37	and	and	CCONJ
mkg-56898	238	38	in	in	ADP
mkg-56898	238	39	vivo	vivo	NOUN
mkg-56898	238	40	.	.	PUNCT
mkg-56898	239	1	int	int	PROPN
mkg-56898	239	2	j	j	PROPN
mkg-56898	239	3	mol	mol	ADP
mkg-56898	239	4	sci	sci	PROPN
mkg-56898	239	5	.	.	PROPN
mkg-56898	239	6	2020	2020	NUM
mkg-56898	239	7	;	;	PUNCT
mkg-56898	239	8	21(16	21(16	NUM
mkg-56898	239	9	):	):	PUNCT
mkg-56898	239	10	5700	5700	NUM
mkg-56898	239	11	.	.	PUNCT
mkg-56898	240	1	14	14	NUM
mkg-56898	240	2	.	.	PUNCT
mkg-56898	241	1	ritmaleni	ritmaleni	NOUN
mkg-56898	241	2	.	.	PUNCT
mkg-56898	241	3	synthesis	synthesis	NOUN
mkg-56898	241	4	of	of	ADP
mkg-56898	241	5	pentagamavunon-0	pentagamavunon-0	NOUN
mkg-56898	241	6	(	(	PUNCT
mkg-56898	241	7	pgv-0	pgv-0	X
mkg-56898	241	8	):	):	PUNCT
mkg-56898	241	9	an	an	DET
mkg-56898	241	10	improved	improved	ADJ
mkg-56898	241	11	technique	technique	NOUN
mkg-56898	241	12	.	.	PUNCT
mkg-56898	242	1	int	int	NOUN
mkg-56898	242	2	j	j	PROPN
mkg-56898	242	3	pharm	pharm	PROPN
mkg-56898	242	4	sci	sci	PROPN
mkg-56898	242	5	rev	rev	PROPN
mkg-56898	242	6	res	re	NOUN
mkg-56898	242	7	.	.	PROPN
mkg-56898	242	8	2016	2016	NUM
mkg-56898	242	9	;	;	PUNCT
mkg-56898	242	10	39(1	39(1	NUM
mkg-56898	242	11	):	):	PUNCT
mkg-56898	242	12	9–11	9–11	NOUN
mkg-56898	242	13	.	.	PUNCT
mkg-56898	243	1	15	15	NUM
mkg-56898	243	2	.	.	X
mkg-56898	243	3	astuti	astuti	PROPN
mkg-56898	243	4	iy	iy	PROPN
mkg-56898	243	5	,	,	PUNCT
mkg-56898	243	6	marchaban	marchaban	PROPN
mkg-56898	243	7	m	m	PROPN
mkg-56898	243	8	,	,	PUNCT
mkg-56898	243	9	martien	martien	PROPN
mkg-56898	243	10	r	r	NOUN
mkg-56898	243	11	,	,	PUNCT
mkg-56898	243	12	nugroho	nugroho	PROPN
mkg-56898	243	13	ae	ae	PROPN
mkg-56898	243	14	.	.	PUNCT
mkg-56898	244	1	design	design	NOUN
mkg-56898	244	2	and	and	CCONJ
mkg-56898	244	3	optimization	optimization	NOUN
mkg-56898	244	4	of	of	ADP
mkg-56898	244	5	self	self	NOUN
mkg-56898	244	6	nano	nano	NOUN
mkg-56898	244	7	-	-	PUNCT
mkg-56898	244	8	emulsifying	emulsify	VERB
mkg-56898	244	9	drug	drug	NOUN
mkg-56898	244	10	delivery	delivery	NOUN
mkg-56898	244	11	system	system	NOUN
mkg-56898	244	12	containing	contain	VERB
mkg-56898	244	13	a	a	DET
mkg-56898	244	14	new	new	ADJ
mkg-56898	244	15	anti	anti	ADJ
mkg-56898	244	16	-	-	ADJ
mkg-56898	244	17	inflamatory	inflamatory	ADJ
mkg-56898	244	18	agent	agent	NOUN
mkg-56898	244	19	pentagamavunon-0	pentagamavunon-0	NUM
mkg-56898	244	20	.	.	PUNCT
mkg-56898	245	1	indones	indone	NOUN
mkg-56898	245	2	j	j	PROPN
mkg-56898	245	3	chem	chem	NOUN
mkg-56898	245	4	.	.	PUNCT
mkg-56898	246	1	2017	2017	NUM
mkg-56898	246	2	;	;	PUNCT
mkg-56898	246	3	17(3	17(3	NUM
mkg-56898	246	4	):	):	PUNCT
mkg-56898	246	5	365	365	NUM
mkg-56898	246	6	.	.	X
mkg-56898	247	1	16	16	NUM
mkg-56898	247	2	.	.	PUNCT
mkg-56898	248	1	marbawat	marbawat	PROPN
mkg-56898	249	1	i	i	PRON
mkg-56898	249	2	d	d	PROPN
mkg-56898	249	3	,	,	PUNCT
mkg-56898	249	4	umniyat	umniyat	PROPN
mkg-56898	249	5	i	i	PROPN
mkg-56898	249	6	sr	sr	PROPN
mkg-56898	249	7	.	.	PUNCT
mkg-56898	250	1	ef	ef	PROPN
mkg-56898	250	2	fects	fect	NOUN
mkg-56898	250	3	of	of	ADP
mkg-56898	250	4	curcumin	curcumin	NOUN
mkg-56898	250	5	and	and	CCONJ
mkg-56898	250	6	pentagamavunon-0	pentagamavunon-0	VERB
mkg-56898	250	7	against	against	ADP
mkg-56898	250	8	dengue-2	dengue-2	NUM
mkg-56898	250	9	virus	virus	NOUN
mkg-56898	250	10	infection	infection	NOUN
mkg-56898	250	11	in	in	ADP
mkg-56898	250	12	vero	vero	PROPN
mkg-56898	250	13	cells	cell	NOUN
mkg-56898	250	14	;	;	PUNCT
mkg-56898	250	15	an	an	DET
mkg-56898	250	16	in	in	ADP
mkg-56898	250	17	vitro	vitro	X
mkg-56898	250	18	study	study	NOUN
mkg-56898	250	19	.	.	PUNCT
mkg-56898	251	1	procedia	procedia	PROPN
mkg-56898	251	2	environ	environ	X
mkg-56898	251	3	sci	sci	PROPN
mkg-56898	251	4	.	.	PROPN
mkg-56898	251	5	2015	2015	NUM
mkg-56898	251	6	;	;	PUNCT
mkg-56898	251	7	23	23	NUM
mkg-56898	251	8	:	:	PUNCT
mkg-56898	251	9	215–21	215–21	NOUN
mkg-56898	251	10	.	.	NOUN
mkg-56898	251	11	17	17	NUM
mkg-56898	251	12	.	.	PUNCT
mkg-56898	252	1	meizarini	meizarini	PROPN
mkg-56898	252	2	a	a	PRON
mkg-56898	252	3	,	,	PUNCT
mkg-56898	252	4	siswandono	siswandono	NOUN
mkg-56898	252	5	s	s	PROPN
mkg-56898	252	6	,	,	PUNCT
mkg-56898	252	7	riawan	riawan	PROPN
mkg-56898	252	8	w	w	PROPN
mkg-56898	252	9	,	,	PUNCT
mkg-56898	252	10	rahayu	rahayu	ADJ
mkg-56898	252	11	rp	rp	NOUN
mkg-56898	252	12	.	.	PUNCT
mkg-56898	253	1	in	in	ADP
mkg-56898	253	2	silico	silico	NOUN
mkg-56898	253	3	and	and	CCONJ
mkg-56898	253	4	in	in	ADP
mkg-56898	253	5	vivo	vivo	ADJ
mkg-56898	253	6	anti	anti	ADJ
mkg-56898	253	7	-	-	ADJ
mkg-56898	253	8	inflammatory	inflammatory	ADJ
mkg-56898	253	9	studies	study	NOUN
mkg-56898	253	10	of	of	ADP
mkg-56898	253	11	curcuminoids	curcuminoid	NOUN
mkg-56898	253	12	,	,	PUNCT
mkg-56898	253	13	turmeric	turmeric	ADJ
mkg-56898	253	14	extract	extract	VERB
mkg-56898	253	15	with	with	ADP
mkg-56898	253	16	zinc	zinc	NOUN
mkg-56898	253	17	oxide	oxide	NOUN
mkg-56898	253	18	,	,	PUNCT
mkg-56898	253	19	and	and	CCONJ
mkg-56898	253	20	eugenol	eugenol	NOUN
mkg-56898	253	21	.	.	PUNCT
mkg-56898	254	1	trop	trop	X
mkg-56898	254	2	j	j	PROPN
mkg-56898	254	3	pharm	pharm	PROPN
mkg-56898	254	4	res	re	NOUN
mkg-56898	254	5	.	.	PROPN
mkg-56898	254	6	2018	2018	NUM
mkg-56898	254	7	;	;	PUNCT
mkg-56898	254	8	17(2	17(2	NUM
mkg-56898	254	9	):	):	PUNCT
mkg-56898	254	10	269	269	NUM
mkg-56898	254	11	.	.	NOUN
mkg-56898	254	12	18	18	NUM
mkg-56898	254	13	.	.	PUNCT
mkg-56898	254	14	liao	liao	PROPN
mkg-56898	254	15	y	y	PROPN
mkg-56898	254	16	,	,	PUNCT
mkg-56898	254	17	wang	wang	PROPN
mkg-56898	254	18	j	j	PROPN
mkg-56898	254	19	,	,	PUNCT
mkg-56898	254	20	jaehnig	jaehnig	PROPN
mkg-56898	254	21	ej	ej	PROPN
mkg-56898	254	22	,	,	PUNCT
mkg-56898	254	23	shi	shi	PROPN
mkg-56898	254	24	z	z	PROPN
mkg-56898	254	25	,	,	PUNCT
mkg-56898	254	26	zhang	zhang	PROPN
mkg-56898	254	27	b.	b.	PROPN
mkg-56898	254	28	webgestalt	webgestalt	VERB
mkg-56898	254	29	2019	2019	NUM
mkg-56898	254	30	:	:	PUNCT
mkg-56898	254	31	gene	gene	NOUN
mkg-56898	254	32	set	set	VERB
mkg-56898	254	33	analysis	analysis	NOUN
mkg-56898	254	34	toolkit	toolkit	NOUN
mkg-56898	254	35	with	with	ADP
mkg-56898	254	36	revamped	revamp	VERB
mkg-56898	254	37	uis	uis	PROPN
mkg-56898	254	38	and	and	CCONJ
mkg-56898	254	39	apis	apis	PROPN
mkg-56898	254	40	.	.	PUNCT
mkg-56898	255	1	nucleic	nucleic	ADJ
mkg-56898	255	2	acids	acid	NOUN
mkg-56898	255	3	res	re	NOUN
mkg-56898	255	4	.	.	PROPN
mkg-56898	255	5	2019	2019	NUM
mkg-56898	255	6	;	;	PUNCT
mkg-56898	255	7	47(w1	47(w1	NUM
mkg-56898	255	8	):	):	PUNCT
mkg-56898	255	9	w199–205	w199–205	PROPN
mkg-56898	255	10	.	.	PROPN
mkg-56898	255	11	19	19	NUM
mkg-56898	255	12	.	.	PUNCT
mkg-56898	255	13	hasbiyani	hasbiyani	PROPN
mkg-56898	255	14	naf	naf	PROPN
mkg-56898	255	15	,	,	PUNCT
mkg-56898	255	16	wulandari	wulandari	PROPN
mkg-56898	255	17	f	f	X
mkg-56898	255	18	,	,	PUNCT
mkg-56898	255	19	nugroho	nugroho	PROPN
mkg-56898	255	20	ep	ep	PROPN
mkg-56898	255	21	,	,	PUNCT
mkg-56898	255	22	hermawan	hermawan	X
mkg-56898	255	23	a	a	X
mkg-56898	255	24	,	,	PUNCT
mkg-56898	255	25	meiyanto	meiyanto	PROPN
mkg-56898	255	26	e.	e.	PROPN
mkg-56898	255	27	bioinformatics	bioinformatics	PROPN
mkg-56898	255	28	analysis	analysis	NOUN
mkg-56898	255	29	confirms	confirm	VERB
mkg-56898	255	30	the	the	DET
mkg-56898	255	31	target	target	NOUN
mkg-56898	255	32	protein	protein	NOUN
mkg-56898	255	33	underlying	underlie	VERB
mkg-56898	255	34	mitotic	mitotic	ADJ
mkg-56898	255	35	catastrophe	catastrophe	NOUN
mkg-56898	255	36	of	of	ADP
mkg-56898	255	37	4t1	4t1	NUM
mkg-56898	255	38	cells	cell	NOUN
mkg-56898	255	39	under	under	ADP
mkg-56898	255	40	combinatorial	combinatorial	ADJ
mkg-56898	255	41	treatment	treatment	NOUN
mkg-56898	255	42	of	of	ADP
mkg-56898	255	43	pgv-1	pgv-1	PUNCT
mkg-56898	255	44	and	and	CCONJ
mkg-56898	255	45	galangin	galangin	NOUN
mkg-56898	255	46	.	.	PUNCT
mkg-56898	256	1	sci	sci	PROPN
mkg-56898	256	2	pharm	pharm	PROPN
mkg-56898	256	3	.	.	PUNCT
mkg-56898	257	1	2021	2021	NUM
mkg-56898	257	2	;	;	PUNCT
mkg-56898	257	3	89(3	89(3	NUM
mkg-56898	257	4	):	):	PUNCT
mkg-56898	257	5	38	38	NUM
mkg-56898	257	6	.	.	NOUN
mkg-56898	257	7	20	20	NUM
mkg-56898	257	8	.	.	PUNCT
mkg-56898	258	1	genecards	genecard	VERB
mkg-56898	258	2	the	the	DET
mkg-56898	258	3	human	human	ADJ
mkg-56898	258	4	gene	gene	NOUN
mkg-56898	258	5	database	database	NOUN
mkg-56898	258	6	.	.	PUNCT
mkg-56898	259	1	ptgs2	ptgs2	PROPN
mkg-56898	259	2	gene	gene	NOUN
mkg-56898	259	3	-	-	PUNCT
mkg-56898	259	4	prostaglandinendoperoxidase	prostaglandinendoperoxidase	NOUN
mkg-56898	259	5	synthase	synthase	NOUN
mkg-56898	259	6	2	2	NUM
mkg-56898	259	7	:	:	PUNCT
mkg-56898	259	8	protein	protein	NOUN
mkg-56898	259	9	coding	coding	NOUN
mkg-56898	259	10	.	.	PUNCT
mkg-56898	260	1	2024	2024	NUM
mkg-56898	260	2	.	.	PUNCT
mkg-56898	261	1	available	available	ADJ
mkg-56898	261	2	from	from	ADP
mkg-56898	261	3	:	:	PUNCT
mkg-56898	261	4	https://www.genecards.org/cgi-bin/carddisp.pl?gene=ptgs2	https://www.genecards.org/cgi-bin/carddisp.pl?gene=ptgs2	PROPN
mkg-56898	261	5	.	.	PUNCT
mkg-56898	262	1	accessed	access	VERB
mkg-56898	262	2	2024	2024	NUM
mkg-56898	262	3	may	may	PROPN
mkg-56898	262	4	12	12	NUM
mkg-56898	262	5	.	.	PUNCT
mkg-56898	263	1	21	21	NUM
mkg-56898	263	2	.	.	PUNCT
mkg-56898	263	3	hu	hu	PROPN
mkg-56898	264	1	q	q	X
mkg-56898	264	2	,	,	PUNCT
mkg-56898	264	3	ecker	ecker	PROPN
mkg-56898	264	4	m.	m.	NOUN
mkg-56898	264	5	overview	overview	NOUN
mkg-56898	264	6	of	of	ADP
mkg-56898	264	7	mmp-13	mmp-13	PROPN
mkg-56898	264	8	as	as	ADP
mkg-56898	264	9	a	a	DET
mkg-56898	264	10	promising	promising	ADJ
mkg-56898	264	11	target	target	NOUN
mkg-56898	264	12	for	for	ADP
mkg-56898	264	13	the	the	DET
mkg-56898	264	14	treatment	treatment	NOUN
mkg-56898	264	15	of	of	ADP
mkg-56898	264	16	osteoarthritis	osteoarthritis	NOUN
mkg-56898	264	17	.	.	PUNCT
mkg-56898	265	1	int	int	PROPN
mkg-56898	265	2	j	j	PROPN
mkg-56898	265	3	mol	mol	ADP
mkg-56898	265	4	sci	sci	PROPN
mkg-56898	265	5	.	.	PROPN
mkg-56898	265	6	2021	2021	NUM
mkg-56898	265	7	;	;	PUNCT
mkg-56898	265	8	22(4	22(4	NUM
mkg-56898	265	9	):	):	PUNCT
mkg-56898	265	10	1742	1742	NUM
mkg-56898	265	11	.	.	PUNCT
mkg-56898	266	1	22	22	NUM
mkg-56898	266	2	.	.	PUNCT
mkg-56898	267	1	loreto	loreto	PROPN
mkg-56898	267	2	c	c	PROPN
mkg-56898	267	3	,	,	PUNCT
mkg-56898	267	4	filetti	filetti	PROPN
mkg-56898	267	5	v	v	PROPN
mkg-56898	267	6	,	,	PUNCT
mkg-56898	267	7	almeida	almeida	PROPN
mkg-56898	267	8	le	le	PROPN
mkg-56898	267	9	,	,	PUNCT
mkg-56898	267	10	la	la	PROPN
mkg-56898	267	11	rosa	rosa	PROPN
mkg-56898	267	12	grm	grm	PROPN
mkg-56898	267	13	,	,	PUNCT
mkg-56898	267	14	leonardi	leonardi	PROPN
mkg-56898	267	15	r	r	PROPN
mkg-56898	267	16	,	,	PUNCT
mkg-56898	267	17	grippaudo	grippaudo	NOUN
mkg-56898	267	18	c	c	NOUN
mkg-56898	267	19	,	,	PUNCT
mkg-56898	267	20	lo	lo	PROPN
mkg-56898	267	21	giudice	giudice	PROPN
mkg-56898	267	22	a.	a.	PROPN
mkg-56898	267	23	mmp-7	mmp-7	NUM
mkg-56898	267	24	and	and	CCONJ
mkg-56898	267	25	mmp-9	mmp-9	NOUN
mkg-56898	267	26	are	be	AUX
mkg-56898	267	27	overexpressed	overexpresse	VERB
mkg-56898	267	28	in	in	ADP
mkg-56898	267	29	the	the	DET
mkg-56898	267	30	synovial	synovial	ADJ
mkg-56898	267	31	tissue	tissue	NOUN
mkg-56898	267	32	from	from	ADP
mkg-56898	267	33	severe	severe	ADJ
mkg-56898	267	34	temporomandibular	temporomandibular	ADJ
mkg-56898	267	35	joint	joint	ADJ
mkg-56898	267	36	dysfunction	dysfunction	NOUN
mkg-56898	267	37	.	.	PUNCT
mkg-56898	268	1	eur	eur	PROPN
mkg-56898	268	2	j	j	PROPN
mkg-56898	268	3	histochem	histochem	PROPN
mkg-56898	268	4	.	.	PUNCT
mkg-56898	269	1	2020	2020	NUM
mkg-56898	269	2	;	;	PUNCT
mkg-56898	269	3	64(2	64(2	NUM
mkg-56898	269	4	):	):	PUNCT
mkg-56898	269	5	3113	3113	NUM
mkg-56898	269	6	.	.	PUNCT
mkg-56898	270	1	23	23	NUM
mkg-56898	270	2	.	.	PUNCT
mkg-56898	270	3	suhartini	suhartini	NOUN
mkg-56898	270	4	,	,	PUNCT
mkg-56898	270	5	narmada	narmada	PROPN
mkg-56898	270	6	ib	ib	PROPN
mkg-56898	270	7	,	,	PUNCT
mkg-56898	270	8	hamzah	hamzah	PROPN
mkg-56898	270	9	z	z	PROPN
mkg-56898	270	10	,	,	PUNCT
mkg-56898	270	11	joewarini	joewarini	PROPN
mkg-56898	270	12	e.	e.	PROPN
mkg-56898	270	13	nfkb	nfkb	PROPN
mkg-56898	270	14	and	and	CCONJ
mkg-56898	270	15	mmp-13	mmp-13	VERB
mkg-56898	270	16	expression	expression	NOUN
mkg-56898	270	17	in	in	ADP
mkg-56898	270	18	condylar	condylar	ADJ
mkg-56898	270	19	cartilage	cartilage	NOUN
mkg-56898	270	20	of	of	ADP
mkg-56898	270	21	temporomandibular	temporomandibular	ADJ
mkg-56898	270	22	joint	joint	NOUN
mkg-56898	270	23	with	with	ADP
mkg-56898	270	24	occlusal	occlusal	ADJ
mkg-56898	270	25	disharmony	disharmony	NOUN
mkg-56898	270	26	in	in	ADP
mkg-56898	270	27	vivo	vivo	NOUN
mkg-56898	270	28	.	.	PUNCT
mkg-56898	271	1	dent	dent	NOUN
mkg-56898	271	2	j.	j.	PROPN
mkg-56898	271	3	2024	2024	NUM
mkg-56898	271	4	;	;	PUNCT
mkg-56898	271	5	57(1	57(1	NUM
mkg-56898	271	6	):	):	PUNCT
mkg-56898	271	7	22–7	22–7	PROPN
mkg-56898	271	8	.	.	PUNCT
mkg-56898	271	9	24	24	NUM
mkg-56898	271	10	.	.	PUNCT
mkg-56898	272	1	hatami	hatami	PROPN
mkg-56898	272	2	m	m	PROPN
mkg-56898	272	3	,	,	PUNCT
mkg-56898	272	4	abdolahi	abdolahi	PROPN
mkg-56898	272	5	m	m	PROPN
mkg-56898	272	6	,	,	PUNCT
mkg-56898	272	7	soveyd	soveyd	PROPN
mkg-56898	272	8	n	n	CCONJ
mkg-56898	272	9	,	,	PUNCT
mkg-56898	272	10	djalali	djalali	PROPN
mkg-56898	272	11	m	m	PROPN
mkg-56898	272	12	,	,	PUNCT
mkg-56898	272	13	togha	togha	PROPN
mkg-56898	272	14	m	m	PROPN
mkg-56898	272	15	,	,	PUNCT
mkg-56898	272	16	honarvar	honarvar	PROPN
mkg-56898	272	17	nm	nm	NOUN
mkg-56898	272	18	.	.	PUNCT
mkg-56898	273	1	molecular	molecular	ADJ
mkg-56898	273	2	mechanisms	mechanism	NOUN
mkg-56898	273	3	of	of	ADP
mkg-56898	273	4	curcumin	curcumin	NOUN
mkg-56898	273	5	in	in	ADP
mkg-56898	273	6	neuroinflammatory	neuroinflammatory	ADJ
mkg-56898	273	7	disorders	disorder	NOUN
mkg-56898	273	8	:	:	PUNCT
mkg-56898	273	9	a	a	DET
mkg-56898	273	10	mini	mini	ADJ
mkg-56898	273	11	review	review	NOUN
mkg-56898	273	12	of	of	ADP
mkg-56898	273	13	current	current	ADJ
mkg-56898	273	14	evidences	evidence	NOUN
mkg-56898	273	15	.	.	PUNCT
mkg-56898	274	1	endocr	endocr	PROPN
mkg-56898	274	2	metab	metab	PROPN
mkg-56898	274	3	immune	immune	ADJ
mkg-56898	274	4	disord	disord	NOUN
mkg-56898	274	5	drug	drug	NOUN
mkg-56898	274	6	targets	target	NOUN
mkg-56898	274	7	.	.	PUNCT
mkg-56898	275	1	2019	2019	NUM
mkg-56898	275	2	;	;	PUNCT
mkg-56898	275	3	19(3	19(3	NUM
mkg-56898	275	4	):	):	PUNCT
mkg-56898	275	5	247–58	247–58	NUM
mkg-56898	275	6	.	.	PUNCT
mkg-56898	276	1	25	25	NUM
mkg-56898	276	2	.	.	PUNCT
mkg-56898	277	1	zeng	zeng	PROPN
mkg-56898	277	2	l	l	PROPN
mkg-56898	277	3	,	,	PUNCT
mkg-56898	277	4	yang	yang	PROPN
mkg-56898	277	5	t	t	PROPN
mkg-56898	277	6	,	,	PUNCT
mkg-56898	277	7	yang	yang	PROPN
mkg-56898	277	8	k	k	PROPN
mkg-56898	277	9	,	,	PUNCT
mkg-56898	277	10	yu	yu	PROPN
mkg-56898	277	11	g	g	PROPN
mkg-56898	277	12	,	,	PUNCT
mkg-56898	277	13	li	li	PROPN
mkg-56898	277	14	j	j	PROPN
mkg-56898	277	15	,	,	PUNCT
mkg-56898	277	16	xiang	xiang	PROPN
mkg-56898	277	17	w	w	PROPN
mkg-56898	277	18	,	,	PUNCT
mkg-56898	277	19	chen	chen	PROPN
mkg-56898	277	20	h.	h.	PROPN
mkg-56898	277	21	efficacy	efficacy	PROPN
mkg-56898	277	22	and	and	CCONJ
mkg-56898	277	23	safety	safety	NOUN
mkg-56898	277	24	of	of	ADP
mkg-56898	277	25	curcumin	curcumin	NOUN
mkg-56898	277	26	and	and	CCONJ
mkg-56898	277	27	curcuma	curcuma	PROPN
mkg-56898	277	28	longa	longa	NOUN
mkg-56898	277	29	extract	extract	NOUN
mkg-56898	277	30	in	in	ADP
mkg-56898	277	31	the	the	DET
mkg-56898	277	32	treatment	treatment	NOUN
mkg-56898	277	33	of	of	ADP
mkg-56898	277	34	arthritis	arthritis	NOUN
mkg-56898	277	35	:	:	PUNCT
mkg-56898	277	36	a	a	DET
mkg-56898	277	37	systematic	systematic	ADJ
mkg-56898	277	38	review	review	NOUN
mkg-56898	277	39	and	and	CCONJ
mkg-56898	277	40	meta	meta	NOUN
mkg-56898	277	41	-	-	PUNCT
mkg-56898	277	42	analysis	analysis	NOUN
mkg-56898	277	43	of	of	ADP
mkg-56898	277	44	randomized	randomized	ADJ
mkg-56898	277	45	controlled	control	VERB
mkg-56898	277	46	trial	trial	NOUN
mkg-56898	277	47	.	.	PUNCT
mkg-56898	278	1	front	front	ADJ
mkg-56898	278	2	immunol	immunol	NOUN
mkg-56898	278	3	.	.	PUNCT
mkg-56898	279	1	2022	2022	NUM
mkg-56898	279	2	;	;	PUNCT
mkg-56898	279	3	13	13	NUM
mkg-56898	279	4	:	:	SYM
mkg-56898	279	5	891822	891822	NUM
mkg-56898	279	6	.	.	PUNCT
mkg-56898	280	1	26	26	NUM
mkg-56898	280	2	.	.	PUNCT
mkg-56898	281	1	shep	shep	PROPN
mkg-56898	281	2	d	d	PROPN
mkg-56898	281	3	,	,	PUNCT
mkg-56898	281	4	khanwelkar	khanwelkar	PROPN
mkg-56898	281	5	c	c	PROPN
mkg-56898	281	6	,	,	PUNCT
mkg-56898	281	7	gade	gade	PROPN
mkg-56898	281	8	p	p	X
mkg-56898	281	9	,	,	PUNCT
mkg-56898	281	10	karad	karad	PROPN
mkg-56898	281	11	s.	s.	PROPN
mkg-56898	281	12	safety	safety	PROPN
mkg-56898	281	13	and	and	CCONJ
mkg-56898	281	14	efficacy	efficacy	NOUN
mkg-56898	281	15	of	of	ADP
mkg-56898	281	16	curcumin	curcumin	NOUN
mkg-56898	281	17	versus	versus	ADP
mkg-56898	281	18	diclofenac	diclofenac	NOUN
mkg-56898	281	19	in	in	ADP
mkg-56898	281	20	knee	knee	NOUN
mkg-56898	281	21	osteoarthritis	osteoarthritis	NOUN
mkg-56898	281	22	:	:	PUNCT
mkg-56898	281	23	a	a	DET
mkg-56898	281	24	randomized	randomize	VERB
mkg-56898	281	25	open	open	ADJ
mkg-56898	281	26	-	-	PUNCT
mkg-56898	281	27	label	label	NOUN
mkg-56898	281	28	parallel	parallel	ADJ
mkg-56898	281	29	-	-	PUNCT
mkg-56898	281	30	arm	arm	NOUN
mkg-56898	281	31	study	study	NOUN
mkg-56898	281	32	.	.	PUNCT
mkg-56898	282	1	trials	trial	NOUN
mkg-56898	282	2	.	.	PUNCT
mkg-56898	283	1	2019	2019	NUM
mkg-56898	283	2	;	;	PUNCT
mkg-56898	284	1	20(1	20(1	NUM
mkg-56898	284	2	):	):	PUNCT
mkg-56898	284	3	214	214	NUM
mkg-56898	284	4	.	.	PUNCT
mkg-56898	285	1	27	27	NUM
mkg-56898	285	2	.	.	PUNCT
mkg-56898	285	3	alfaro	alfaro	PROPN
mkg-56898	285	4	ra	ra	PROPN
mkg-56898	285	5	,	,	PUNCT
mkg-56898	285	6	davis	davis	PROPN
mkg-56898	285	7	dd	dd	PROPN
mkg-56898	285	8	.	.	PROPN
mkg-56898	285	9	diclofenac	diclofenac	PROPN
mkg-56898	285	10	.	.	PUNCT
mkg-56898	286	1	statpearls	statpearls	PROPN
mkg-56898	286	2	publishing	publishing	NOUN
mkg-56898	286	3	;	;	PUNCT
mkg-56898	286	4	2023	2023	NUM
mkg-56898	286	5	.	.	X
mkg-56898	287	1	28	28	NUM
mkg-56898	287	2	.	.	PUNCT
mkg-56898	288	1	kotha	kotha	PROPN
mkg-56898	288	2	rr	rr	PROPN
mkg-56898	288	3	,	,	PUNCT
mkg-56898	288	4	luthria	luthria	PROPN
mkg-56898	288	5	dl	dl	PROPN
mkg-56898	288	6	.	.	PROPN
mkg-56898	288	7	curcumin	curcumin	PROPN
mkg-56898	288	8	:	:	PUNCT
mkg-56898	288	9	biological	biological	ADJ
mkg-56898	288	10	,	,	PUNCT
mkg-56898	288	11	pharmaceutical	pharmaceutical	NOUN
mkg-56898	288	12	,	,	PUNCT
mkg-56898	288	13	nutraceutical	nutraceutical	ADJ
mkg-56898	288	14	,	,	PUNCT
mkg-56898	288	15	and	and	CCONJ
mkg-56898	288	16	analytical	analytical	ADJ
mkg-56898	288	17	aspects	aspect	NOUN
mkg-56898	288	18	.	.	PUNCT
mkg-56898	289	1	molecules	molecule	NOUN
mkg-56898	289	2	.	.	PUNCT
mkg-56898	290	1	2019	2019	NUM
mkg-56898	290	2	;	;	PUNCT
mkg-56898	290	3	24(16	24(16	NUM
mkg-56898	290	4	):	):	PUNCT
mkg-56898	290	5	2930	2930	NUM
mkg-56898	290	6	.	.	PUNCT
mkg-56898	291	1	29	29	NUM
mkg-56898	291	2	.	.	PUNCT
mkg-56898	292	1	henrotin	henrotin	VERB
mkg-56898	292	2	y	y	PROPN
mkg-56898	292	3	,	,	PUNCT
mkg-56898	292	4	priem	priem	PROPN
mkg-56898	292	5	f	f	NOUN
mkg-56898	292	6	,	,	PUNCT
mkg-56898	292	7	mobasheri	mobasheri	PROPN
mkg-56898	292	8	a.	a.	NOUN
mkg-56898	292	9	curcumin	curcumin	PROPN
mkg-56898	292	10	:	:	PUNCT
mkg-56898	292	11	a	a	DET
mkg-56898	292	12	new	new	ADJ
mkg-56898	292	13	paradigm	paradigm	NOUN
mkg-56898	292	14	and	and	CCONJ
mkg-56898	292	15	therapeutic	therapeutic	ADJ
mkg-56898	292	16	opportunity	opportunity	NOUN
mkg-56898	292	17	for	for	ADP
mkg-56898	292	18	the	the	DET
mkg-56898	292	19	treatment	treatment	NOUN
mkg-56898	292	20	of	of	ADP
mkg-56898	292	21	osteoarthritis	osteoarthritis	NOUN
mkg-56898	292	22	:	:	PUNCT
mkg-56898	292	23	curcumin	curcumin	NOUN
mkg-56898	292	24	for	for	ADP
mkg-56898	292	25	osteoarthritis	osteoarthritis	NOUN
mkg-56898	292	26	management	management	NOUN
mkg-56898	292	27	.	.	PUNCT
mkg-56898	293	1	springerplus	springerplus	PROPN
mkg-56898	293	2	.	.	PROPN
mkg-56898	293	3	2013	2013	NUM
mkg-56898	293	4	;	;	PUNCT
mkg-56898	293	5	2(1	2(1	NUM
mkg-56898	293	6	):	):	PUNCT
mkg-56898	293	7	56	56	NUM
mkg-56898	293	8	.	.	NOUN
mkg-56898	293	9	30	30	NUM
mkg-56898	293	10	.	.	PUNCT
mkg-56898	294	1	wang	wang	PROPN
mkg-56898	294	2	j	j	PROPN
mkg-56898	294	3	,	,	PUNCT
mkg-56898	294	4	ma	ma	PROPN
mkg-56898	294	5	j	j	PROPN
mkg-56898	294	6	,	,	PUNCT
mkg-56898	294	7	gu	gu	ADP
mkg-56898	294	8	j	j	PROPN
mkg-56898	294	9	-	-	PROPN
mkg-56898	294	10	h	h	PROPN
mkg-56898	294	11	,	,	PUNCT
mkg-56898	294	12	wang	wang	PROPN
mkg-56898	294	13	f	f	PROPN
mkg-56898	294	14	-	-	PROPN
mkg-56898	294	15	y	y	PROPN
mkg-56898	294	16	,	,	PUNCT
mkg-56898	294	17	shang	shang	PROPN
mkg-56898	294	18	x	x	PROPN
mkg-56898	294	19	-	-	PUNCT
mkg-56898	294	20	s	s	PROPN
mkg-56898	294	21	,	,	PUNCT
mkg-56898	294	22	tao	tao	PROPN
mkg-56898	294	23	h	h	PROPN
mkg-56898	294	24	-	-	PUNCT
mkg-56898	294	25	r	r	NOUN
mkg-56898	294	26	,	,	PUNCT
mkg-56898	294	27	wang	wang	PROPN
mkg-56898	294	28	x.	x.	NOUN
mkg-56898	294	29	regulation	regulation	NOUN
mkg-56898	294	30	of	of	ADP
mkg-56898	294	31	type	type	NOUN
mkg-56898	294	32	ii	ii	PROPN
mkg-56898	294	33	collagen	collagen	NOUN
mkg-56898	294	34	,	,	PUNCT
mkg-56898	294	35	matrix	matrix	NOUN
mkg-56898	294	36	metalloproteinase-13	metalloproteinase-13	NOUN
mkg-56898	294	37	and	and	CCONJ
mkg-56898	294	38	cell	cell	NOUN
mkg-56898	294	39	proliferation	proliferation	NOUN
mkg-56898	294	40	by	by	ADP
mkg-56898	294	41	interleukin-1β	interleukin-1β	PROPN
mkg-56898	294	42	is	be	AUX
mkg-56898	294	43	mediated	mediate	VERB
mkg-56898	294	44	by	by	ADP
mkg-56898	294	45	curcumin	curcumin	NOUN
mkg-56898	294	46	via	via	ADP
mkg-56898	294	47	inhibition	inhibition	NOUN
mkg-56898	294	48	of	of	ADP
mkg-56898	294	49	nf	nf	ADJ
mkg-56898	294	50	-	-	PUNCT
mkg-56898	294	51	κb	κb	NOUN
mkg-56898	294	52	signaling	signal	VERB
mkg-56898	294	53	in	in	ADP
mkg-56898	294	54	rat	rat	NOUN
mkg-56898	294	55	chondrocytes	chondrocyte	NOUN
mkg-56898	294	56	.	.	PUNCT
mkg-56898	295	1	mol	mol	ADP
mkg-56898	295	2	med	med	PROPN
mkg-56898	295	3	rep	rep	PROPN
mkg-56898	295	4	.	.	PROPN
mkg-56898	295	5	2017	2017	NUM
mkg-56898	295	6	;	;	PUNCT
mkg-56898	295	7	16(2	16(2	NUM
mkg-56898	295	8	):	):	PUNCT
mkg-56898	295	9	1837–45	1837–45	NOUN
mkg-56898	295	10	.	.	PUNCT
mkg-56898	296	1	31	31	NUM
mkg-56898	296	2	.	.	PUNCT
mkg-56898	297	1	shakibaei	shakibaei	PROPN
mkg-56898	297	2	m	m	PROPN
mkg-56898	297	3	,	,	PUNCT
mkg-56898	297	4	mobasheri	mobasheri	PROPN
mkg-56898	297	5	a	a	DET
mkg-56898	297	6	,	,	PUNCT
mkg-56898	297	7	buhrmann	buhrmann	PROPN
mkg-56898	297	8	c.	c.	PROPN
mkg-56898	297	9	curcumin	curcumin	PROPN
mkg-56898	297	10	synergizes	synergize	VERB
mkg-56898	297	11	with	with	ADP
mkg-56898	297	12	resveratrol	resveratrol	NOUN
mkg-56898	297	13	to	to	PART
mkg-56898	297	14	stimulate	stimulate	VERB
mkg-56898	297	15	the	the	DET
mkg-56898	297	16	mapk	mapk	NOUN
mkg-56898	297	17	signaling	signal	VERB
mkg-56898	297	18	pathway	pathway	NOUN
mkg-56898	297	19	in	in	ADP
mkg-56898	297	20	human	human	ADJ
mkg-56898	297	21	articular	articular	ADJ
mkg-56898	297	22	chondrocytes	chondrocyte	NOUN
mkg-56898	297	23	in	in	ADP
mkg-56898	297	24	vitro	vitro	VERB
mkg-56898	297	25	.	.	PUNCT
mkg-56898	298	1	genes	gene	NOUN
mkg-56898	298	2	nutr	nutr	NOUN
mkg-56898	298	3	.	.	PROPN
mkg-56898	298	4	2011	2011	NUM
mkg-56898	298	5	;	;	PUNCT
mkg-56898	298	6	6(2	6(2	NUM
mkg-56898	298	7	):	):	PUNCT
mkg-56898	298	8	171–9	171–9	NUM
mkg-56898	298	9	.	.	NOUN
mkg-56898	298	10	32	32	NUM
mkg-56898	298	11	.	.	PUNCT
mkg-56898	299	1	perotto	perotto	PROPN
mkg-56898	299	2	jh	jh	PROPN
mkg-56898	299	3	,	,	PUNCT
mkg-56898	299	4	camejo	camejo	PROPN
mkg-56898	299	5	f	f	PROPN
mkg-56898	299	6	de	de	PROPN
mkg-56898	299	7	a	a	PROPN
mkg-56898	299	8	,	,	PUNCT
mkg-56898	299	9	doetzer	doetzer	NOUN
mkg-56898	299	10	ad	ad	NOUN
mkg-56898	299	11	,	,	PUNCT
mkg-56898	299	12	almeida	almeida	PROPN
mkg-56898	299	13	le	le	PROPN
mkg-56898	299	14	,	,	PUNCT
mkg-56898	299	15	azevedo	azevedo	PROPN
mkg-56898	299	16	m	m	PROPN
mkg-56898	299	17	,	,	PUNCT
mkg-56898	299	18	olandoski	olandoski	PROPN
mkg-56898	299	19	m	m	PROPN
mkg-56898	299	20	,	,	PUNCT
mkg-56898	299	21	noronha	noronha	NOUN
mkg-56898	299	22	l	l	NOUN
mkg-56898	299	23	,	,	PUNCT
mkg-56898	299	24	trevilatto	trevilatto	NOUN
mkg-56898	299	25	pc	pc	NOUN
mkg-56898	299	26	.	.	PUNCT
mkg-56898	300	1	expression	expression	NOUN
mkg-56898	300	2	of	of	ADP
mkg-56898	300	3	mmp13	mmp13	NOUN
mkg-56898	300	4	in	in	ADP
mkg-56898	300	5	human	human	ADJ
mkg-56898	300	6	temporomandibular	temporomandibular	ADJ
mkg-56898	300	7	joint	joint	ADJ
mkg-56898	300	8	disc	disc	NOUN
mkg-56898	300	9	derangement	derangement	NOUN
mkg-56898	300	10	and	and	CCONJ
mkg-56898	300	11	osteoarthritis	osteoarthritis	NOUN
mkg-56898	300	12	.	.	PUNCT
mkg-56898	301	1	cranio	cranio	PROPN
mkg-56898	301	2	®	®	PROPN
mkg-56898	301	3	.	.	PROPN
mkg-56898	301	4	2018	2018	NUM
mkg-56898	301	5	;	;	PUNCT
mkg-56898	301	6	36(3	36(3	NUM
mkg-56898	301	7	):	):	PUNCT
mkg-56898	301	8	161–6	161–6	NUM
mkg-56898	301	9	.	.	PUNCT
mkg-56898	302	1	33	33	NUM
mkg-56898	302	2	.	.	PUNCT
mkg-56898	303	1	farmasyanti	farmasyanti	PROPN
mkg-56898	303	2	ca	ca	PROPN
mkg-56898	303	3	,	,	PUNCT
mkg-56898	303	4	kuijpers	kuijper	NOUN
mkg-56898	303	5	-	-	PUNCT
mkg-56898	303	6	jagtman	jagtman	PROPN
mkg-56898	303	7	am	be	AUX
mkg-56898	303	8	,	,	PUNCT
mkg-56898	303	9	susilowati	susilowati	NOUN
mkg-56898	303	10	h	h	NOUN
mkg-56898	303	11	,	,	PUNCT
mkg-56898	303	12	meiyanto	meiyanto	PROPN
mkg-56898	303	13	e.	e.	PROPN
mkg-56898	303	14	effects	effect	NOUN
mkg-56898	303	15	of	of	ADP
mkg-56898	303	16	pentagamavunon-0	pentagamavunon-0	NOUN
mkg-56898	303	17	(	(	PUNCT
mkg-56898	303	18	pgv-0	pgv-0	NOUN
mkg-56898	303	19	)	)	PUNCT
mkg-56898	303	20	as	as	ADP
mkg-56898	303	21	alternative	alternative	ADJ
mkg-56898	303	22	analgesics	analgesic	NOUN
mkg-56898	303	23	on	on	ADP
mkg-56898	303	24	orthodontic	orthodontic	ADJ
mkg-56898	303	25	tooth	tooth	NOUN
mkg-56898	303	26	movement	movement	NOUN
mkg-56898	303	27	in	in	ADP
mkg-56898	303	28	rats	rat	NOUN
mkg-56898	303	29	.	.	PUNCT
mkg-56898	304	1	padjadjaran	padjadjaran	PROPN
mkg-56898	304	2	j	j	PROPN
mkg-56898	304	3	dent	dent	PROPN
mkg-56898	304	4	.	.	PUNCT
mkg-56898	305	1	2019	2019	NUM
mkg-56898	305	2	;	;	PUNCT
mkg-56898	305	3	31(3	31(3	NUM
mkg-56898	305	4	):	):	PUNCT
mkg-56898	305	5	152	152	NUM
mkg-56898	305	6	.	.	PUNCT
mkg-56898	306	1	34	34	NUM
mkg-56898	306	2	.	.	PUNCT
mkg-56898	306	3	bhagyashree	bhagyashree	PROPN
mkg-56898	306	4	a	a	PROPN
mkg-56898	306	5	,	,	PUNCT
mkg-56898	306	6	manikkoth	manikkoth	NOUN
mkg-56898	306	7	s	s	PROPN
mkg-56898	306	8	,	,	PUNCT
mkg-56898	306	9	sequeira	sequeira	PROPN
mkg-56898	306	10	m	m	PROPN
mkg-56898	306	11	,	,	PUNCT
mkg-56898	306	12	nayak	nayak	PROPN
mkg-56898	306	13	r	r	PROPN
mkg-56898	306	14	,	,	PUNCT
mkg-56898	306	15	rao	rao	PROPN
mkg-56898	306	16	sn	sn	PROPN
mkg-56898	306	17	.	.	PUNCT
mkg-56898	307	1	central	central	ADJ
mkg-56898	307	2	dopaminergic	dopaminergic	ADJ
mkg-56898	307	3	system	system	NOUN
mkg-56898	307	4	plays	play	VERB
mkg-56898	307	5	a	a	DET
mkg-56898	307	6	role	role	NOUN
mkg-56898	307	7	in	in	ADP
mkg-56898	307	8	the	the	DET
mkg-56898	307	9	analgesic	analgesic	ADJ
mkg-56898	307	10	action	action	NOUN
mkg-56898	307	11	of	of	ADP
mkg-56898	307	12	paracetamol	paracetamol	NOUN
mkg-56898	307	13	:	:	PUNCT
mkg-56898	307	14	preclinical	preclinical	ADJ
mkg-56898	307	15	evidence	evidence	NOUN
mkg-56898	307	16	.	.	PUNCT
mkg-56898	308	1	indian	indian	PROPN
mkg-56898	308	2	j	j	PROPN
mkg-56898	308	3	pharmacol	pharmacol	PROPN
mkg-56898	308	4	.	.	PROPN
mkg-56898	308	5	2017	2017	NUM
mkg-56898	308	6	;	;	PUNCT
mkg-56898	308	7	49(1	49(1	NUM
mkg-56898	308	8	):	):	PUNCT
mkg-56898	308	9	21–5	21–5	PROPN
mkg-56898	308	10	.	.	PUNCT
mkg-56898	309	1	35	35	NUM
mkg-56898	309	2	.	.	PUNCT
mkg-56898	310	1	lee	lee	PROPN
mkg-56898	310	2	yt	yt	PROPN
mkg-56898	310	3	,	,	PUNCT
mkg-56898	310	4	yunus	yunus	PROPN
mkg-56898	310	5	mhm	mhm	INTJ
mkg-56898	310	6	,	,	PUNCT
mkg-56898	310	7	ugusman	ugusman	PROPN
mkg-56898	310	8	a	a	PROPN
mkg-56898	310	9	,	,	PUNCT
mkg-56898	310	10	yazid	yazid	PROPN
mkg-56898	310	11	md	md	PROPN
mkg-56898	310	12	.	.	PROPN
mkg-56898	310	13	natural	natural	ADJ
mkg-56898	310	14	compounds	compound	NOUN
mkg-56898	310	15	affecting	affect	VERB
mkg-56898	310	16	inflammatory	inflammatory	ADJ
mkg-56898	310	17	pathways	pathway	NOUN
mkg-56898	310	18	of	of	ADP
mkg-56898	310	19	osteoarthritis	osteoarthritis	NOUN
mkg-56898	310	20	.	.	PUNCT
mkg-56898	311	1	antioxidants	antioxidant	NOUN
mkg-56898	311	2	(	(	PUNCT
mkg-56898	311	3	basel	basel	PROPN
mkg-56898	311	4	,	,	PUNCT
mkg-56898	311	5	switzerland	switzerland	PROPN
mkg-56898	311	6	)	)	PUNCT
mkg-56898	311	7	.	.	PUNCT
mkg-56898	312	1	2022	2022	NUM
mkg-56898	312	2	;	;	PUNCT
mkg-56898	312	3	11(9	11(9	NUM
mkg-56898	312	4	):	):	PUNCT
mkg-56898	312	5	1722	1722	NUM
mkg-56898	312	6	.	.	PUNCT
mkg-56898	313	1	copyright	copyright	NOUN
mkg-56898	313	2	©	©	PROPN
mkg-56898	313	3	2025	2025	NUM
mkg-56898	313	4	dental	dental	ADJ
mkg-56898	313	5	journal	journal	NOUN
mkg-56898	313	6	(	(	PUNCT
mkg-56898	313	7	majalah	majalah	PROPN
mkg-56898	313	8	kedokteran	kedokteran	PROPN
mkg-56898	313	9	gigi	gigi	PROPN
mkg-56898	313	10	)	)	PUNCT
mkg-56898	314	1	p	p	X
mkg-56898	314	2	-	-	PUNCT
mkg-56898	314	3	issn	issn	NOUN
mkg-56898	314	4	:	:	PUNCT
mkg-56898	314	5	1978	1978	NUM
mkg-56898	314	6	-	-	SYM
mkg-56898	314	7	3728	3728	NUM
mkg-56898	314	8	;	;	PUNCT
mkg-56898	314	9	e	e	X
mkg-56898	314	10	-	-	PUNCT
mkg-56898	314	11	issn	issn	ADJ
mkg-56898	314	12	:	:	PUNCT
mkg-56898	314	13	2442	2442	NUM
mkg-56898	314	14	-	-	SYM
mkg-56898	314	15	9740	9740	NUM
mkg-56898	314	16	.	.	PUNCT
mkg-56898	315	1	accredited	accredit	VERB
mkg-56898	315	2	no	no	INTJ
mkg-56898	315	3	.	.	PROPN
mkg-56898	316	1	158	158	NUM
mkg-56898	316	2	/	/	SYM
mkg-56898	316	3	e	e	NOUN
mkg-56898	316	4	/	/	SYM
mkg-56898	316	5	kpt/2021	kpt/2021	NOUN
mkg-56898	316	6	.	.	PUNCT
mkg-56898	317	1	open	open	ADJ
mkg-56898	317	2	access	access	NOUN
mkg-56898	317	3	under	under	ADP
mkg-56898	317	4	cc	cc	NOUN
mkg-56898	317	5	-	-	PUNCT
mkg-56898	317	6	by	by	ADP
mkg-56898	317	7	-	-	PUNCT
mkg-56898	317	8	sa	sa	NOUN
mkg-56898	317	9	license	license	NOUN
mkg-56898	317	10	.	.	PUNCT
mkg-56898	318	1	available	available	ADJ
mkg-56898	318	2	at	at	ADP
mkg-56898	318	3	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	318	4	doi	doi	NOUN
mkg-56898	318	5	:	:	PUNCT
mkg-56898	318	6	10.20473	10.20473	NUM
mkg-56898	318	7	/	/	SYM
mkg-56898	318	8	j.djmkg.v58.i4.p367–375	j.djmkg.v58.i4.p367–375	NOUN
mkg-56898	318	9	https://www.genecards.org/cgi-bin/carddisp.pl?gene=ptgs2	https://www.genecards.org/cgi-bin/carddisp.pl?gene=ptgs2	PROPN
mkg-56898	318	10	https://e-journal.unair.ac.id/mkg/index	https://e-journal.unair.ac.id/mkg/index	NOUN
mkg-56898	318	11	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	https://doi.org/10.20473/j.djmkg.v58.i4.p367-375	PROPN