id	sid	tid	token	lemma	pos
mkg-872	1	1	mkgs	mkgs	ADJ
mkg-872	1	2	vol	vol	NOUN
mkg-872	1	3	44	44	NUM
mkg-872	1	4	no	no	PRON
mkg-872	1	5	2	2	NUM
mkg-872	1	6	april	april	PROPN
mkg-872	1	7	-	-	PUNCT
mkg-872	1	8	juni	juni	PROPN
mkg-872	1	9	2011.indd	2011.indd	NUM
mkg-872	1	10	77	77	NUM
mkg-872	1	11	vol	vol	NOUN
mkg-872	1	12	.	.	PROPN
mkg-872	1	13	44	44	NUM
mkg-872	1	14	.	.	PUNCT
mkg-872	2	1	no	no	INTJ
mkg-872	2	2	.	.	NOUN
mkg-872	2	3	2	2	NUM
mkg-872	2	4	june	june	PROPN
mkg-872	2	5	2011	2011	NUM
mkg-872	2	6	saliva	saliva	NOUN
mkg-872	2	7	as	as	ADP
mkg-872	2	8	a	a	DET
mkg-872	2	9	future	future	ADJ
mkg-872	2	10	potential	potential	ADJ
mkg-872	2	11	predictor	predictor	NOUN
mkg-872	2	12	for	for	ADP
mkg-872	2	13	various	various	ADJ
mkg-872	2	14	periodontal	periodontal	ADJ
mkg-872	2	15	diseases	disease	NOUN
mkg-872	2	16	zahreni	zahreni	ADJ
mkg-872	2	17	-	-	PUNCT
mkg-872	2	18	hamzah	hamzah	PROPN
mkg-872	2	19	laboratory	laboratory	NOUN
mkg-872	2	20	of	of	ADP
mkg-872	2	21	biomedic	biomedic	ADJ
mkg-872	2	22	faculty	faculty	NOUN
mkg-872	2	23	of	of	ADP
mkg-872	2	24	dentistry	dentistry	NOUN
mkg-872	2	25	,	,	PUNCT
mkg-872	2	26	jember	jember	PROPN
mkg-872	2	27	university	university	PROPN
mkg-872	2	28	jember	jember	PROPN
mkg-872	2	29	indonesia	indonesia	PROPN
mkg-872	2	30	abstract	abstract	PROPN
mkg-872	2	31	background	background	NOUN
mkg-872	2	32	:	:	PUNCT
mkg-872	2	33	there	there	PRON
mkg-872	2	34	are	be	VERB
mkg-872	2	35	many	many	ADJ
mkg-872	2	36	diagnostic	diagnostic	ADJ
mkg-872	2	37	biomarkers	biomarker	NOUN
mkg-872	2	38	have	have	AUX
mkg-872	2	39	been	be	AUX
mkg-872	2	40	found	find	VERB
mkg-872	2	41	in	in	ADP
mkg-872	2	42	saliva	saliva	NOUN
mkg-872	2	43	.	.	PUNCT
mkg-872	3	1	saliva	saliva	NOUN
mkg-872	3	2	contains	contain	VERB
mkg-872	3	3	a	a	DET
mkg-872	3	4	wide	wide	ADJ
mkg-872	3	5	variety	variety	NOUN
mkg-872	3	6	of	of	ADP
mkg-872	3	7	proteins	protein	NOUN
mkg-872	3	8	,	,	PUNCT
mkg-872	3	9	including	include	VERB
mkg-872	3	10	bacteria	bacteria	NOUN
mkg-872	3	11	and	and	CCONJ
mkg-872	3	12	products	product	NOUN
mkg-872	3	13	,	,	PUNCT
mkg-872	3	14	enzymes	enzyme	NOUN
mkg-872	3	15	,	,	PUNCT
mkg-872	3	16	inflammatory	inflammatory	ADJ
mkg-872	3	17	mediators	mediator	NOUN
mkg-872	3	18	and	and	CCONJ
mkg-872	3	19	host	host	NOUN
mkg-872	3	20	response	response	NOUN
mkg-872	3	21	modifiers	modifier	NOUN
mkg-872	3	22	,	,	PUNCT
mkg-872	3	23	products	product	NOUN
mkg-872	3	24	of	of	ADP
mkg-872	3	25	tissue	tissue	NOUN
mkg-872	3	26	breakdown	breakdown	NOUN
mkg-872	3	27	.	.	PUNCT
mkg-872	4	1	purpose	purpose	NOUN
mkg-872	4	2	:	:	PUNCT
mkg-872	4	3	the	the	DET
mkg-872	4	4	purpose	purpose	NOUN
mkg-872	4	5	of	of	ADP
mkg-872	4	6	the	the	DET
mkg-872	4	7	study	study	NOUN
mkg-872	4	8	was	be	AUX
mkg-872	4	9	studied	study	VERB
mkg-872	4	10	current	current	ADJ
mkg-872	4	11	development	development	NOUN
mkg-872	4	12	of	of	ADP
mkg-872	4	13	diagnostic	diagnostic	ADJ
mkg-872	4	14	biomarkers	biomarker	NOUN
mkg-872	4	15	in	in	ADP
mkg-872	4	16	saliva	saliva	NOUN
mkg-872	4	17	that	that	PRON
mkg-872	4	18	will	will	AUX
mkg-872	4	19	lead	lead	VERB
mkg-872	4	20	to	to	ADP
mkg-872	4	21	the	the	DET
mkg-872	4	22	development	development	NOUN
mkg-872	4	23	of	of	ADP
mkg-872	4	24	simple	simple	ADJ
mkg-872	4	25	and	and	CCONJ
mkg-872	4	26	accurate	accurate	ADJ
mkg-872	4	27	diagnostic	diagnostic	ADJ
mkg-872	4	28	tools	tool	NOUN
mkg-872	4	29	for	for	ADP
mkg-872	4	30	periodental	periodental	ADJ
mkg-872	4	31	disease	disease	NOUN
mkg-872	4	32	.	.	PUNCT
mkg-872	5	1	reviews	review	NOUN
mkg-872	5	2	:	:	PUNCT
mkg-872	5	3	specifically	specifically	ADV
mkg-872	5	4	,	,	PUNCT
mkg-872	5	5	the	the	DET
mkg-872	5	6	salivary	salivary	ADJ
mkg-872	5	7	biomarkers	biomarker	NOUN
mkg-872	5	8	divided	divide	VERB
mkg-872	5	9	for	for	ADP
mkg-872	5	10	three	three	NUM
mkg-872	5	11	aspects	aspect	NOUN
mkg-872	5	12	of	of	ADP
mkg-872	5	13	periodontitis	periodontitis	NOUN
mkg-872	5	14	i.e.	i.e.	X
mkg-872	5	15	inflammation	inflammation	NOUN
mkg-872	5	16	,	,	PUNCT
mkg-872	5	17	collagen	collagen	NOUN
mkg-872	5	18	degradation	degradation	NOUN
mkg-872	5	19	and	and	CCONJ
mkg-872	5	20	bone	bone	NOUN
mkg-872	5	21	turnover	turnover	NOUN
mkg-872	5	22	,	,	PUNCT
mkg-872	5	23	correlated	correlate	VERB
mkg-872	5	24	with	with	ADP
mkg-872	5	25	clinical	clinical	ADJ
mkg-872	5	26	features	feature	NOUN
mkg-872	5	27	of	of	ADP
mkg-872	5	28	periodontal	periodontal	ADJ
mkg-872	5	29	disease	disease	NOUN
mkg-872	5	30	.	.	PUNCT
mkg-872	6	1	the	the	DET
mkg-872	6	2	diagnostic	diagnostic	ADJ
mkg-872	6	3	biomarkers	biomarker	NOUN
mkg-872	6	4	is	be	AUX
mkg-872	6	5	in	in	ADP
mkg-872	6	6	saliva	saliva	NOUN
mkg-872	6	7	,	,	PUNCT
mkg-872	6	8	such	such	ADJ
mkg-872	6	9	as	as	ADP
mkg-872	6	10	enzyme	enzyme	NOUN
mkg-872	6	11	,	,	PUNCT
mkg-872	6	12	immunoglobulin	immunoglobulin	NOUN
mkg-872	6	13	,	,	PUNCT
mkg-872	6	14	cytokines	cytokine	NOUN
mkg-872	6	15	,	,	PUNCT
mkg-872	6	16	bacteria	bacteria	NOUN
mkg-872	6	17	and	and	CCONJ
mkg-872	6	18	bacterial	bacterial	ADJ
mkg-872	6	19	products	product	NOUN
mkg-872	6	20	,	,	PUNCT
mkg-872	6	21	hormones	hormone	NOUN
mkg-872	6	22	.	.	PUNCT
mkg-872	7	1	for	for	ADP
mkg-872	7	2	the	the	DET
mkg-872	7	3	past	past	ADJ
mkg-872	7	4	two	two	NUM
mkg-872	7	5	decades	decade	NOUN
mkg-872	7	6	,	,	PUNCT
mkg-872	7	7	oral	oral	ADJ
mkg-872	7	8	health	health	NOUN
mkg-872	7	9	researchers	researcher	NOUN
mkg-872	7	10	have	have	AUX
mkg-872	7	11	been	be	AUX
mkg-872	7	12	developing	develop	VERB
mkg-872	7	13	salivary	salivary	ADJ
mkg-872	7	14	diagnostic	diagnostic	ADJ
mkg-872	7	15	tools	tool	NOUN
mkg-872	7	16	to	to	PART
mkg-872	7	17	monitor	monitor	VERB
mkg-872	7	18	oral	oral	ADJ
mkg-872	7	19	diseases	disease	NOUN
mkg-872	7	20	.	.	PUNCT
mkg-872	8	1	conclusion	conclusion	NOUN
mkg-872	8	2	:	:	PUNCT
mkg-872	8	3	the	the	DET
mkg-872	8	4	indicators	indicator	NOUN
mkg-872	8	5	of	of	ADP
mkg-872	8	6	acute	acute	NOUN
mkg-872	8	7	periodontitis	periodontitis	NOUN
mkg-872	8	8	can	can	AUX
mkg-872	8	9	detect	detect	VERB
mkg-872	8	10	with	with	ADP
mkg-872	8	11	ß	ß	NOUN
mkg-872	8	12	-	-	ADJ
mkg-872	8	13	glucuronidase	glucuronidase	NOUN
mkg-872	8	14	and	and	CCONJ
mkg-872	8	15	ast	ast	NOUN
mkg-872	8	16	,	,	PUNCT
mkg-872	8	17	il-1β	il-1β	PROPN
mkg-872	8	18	,	,	PUNCT
mkg-872	8	19	and	and	CCONJ
mkg-872	8	20	mmp-8	mmp-8	ADV
mkg-872	8	21	,	,	PUNCT
mkg-872	8	22	whereas	whereas	SCONJ
mkg-872	8	23	indicators	indicator	NOUN
mkg-872	8	24	for	for	ADP
mkg-872	8	25	chronic	chronic	ADJ
mkg-872	8	26	periodontitis	periodontitis	NOUN
mkg-872	8	27	can	can	AUX
mkg-872	8	28	detect	detect	VERB
mkg-872	8	29	with	with	ADP
mkg-872	8	30	alp	alp	PROPN
mkg-872	8	31	.	.	PUNCT
mkg-872	9	1	the	the	DET
mkg-872	9	2	indicators	indicator	NOUN
mkg-872	9	3	for	for	ADP
mkg-872	9	4	collagen	collagen	NOUN
mkg-872	9	5	degradation	degradation	NOUN
mkg-872	9	6	and	and	CCONJ
mkg-872	9	7	bone	bone	NOUN
mkg-872	9	8	turnover	turnover	NOUN
mkg-872	9	9	suggest	suggest	VERB
mkg-872	9	10	ictp	ictp	ADJ
mkg-872	9	11	,	,	PUNCT
mkg-872	9	12	fibronectin	fibronectin	NOUN
mkg-872	9	13	fragments	fragment	NOUN
mkg-872	9	14	,	,	PUNCT
mkg-872	9	15	and	and	CCONJ
mkg-872	9	16	osteonectin	osteonectin	X
mkg-872	9	17	.	.	PUNCT
mkg-872	10	1	the	the	DET
mkg-872	10	2	indicators	indicator	NOUN
mkg-872	10	3	of	of	ADP
mkg-872	10	4	severity	severity	NOUN
mkg-872	10	5	of	of	ADP
mkg-872	10	6	periodontitis	periodontitis	NOUN
mkg-872	10	7	especially	especially	ADV
mkg-872	10	8	can	can	AUX
mkg-872	10	9	be	be	AUX
mkg-872	10	10	predict	predict	VERB
mkg-872	10	11	by	by	ADP
mkg-872	10	12	b.	b.	PROPN
mkg-872	10	13	forsythus	forsythus	PROPN
mkg-872	10	14	.	.	PUNCT
mkg-872	11	1	key	key	ADJ
mkg-872	11	2	words	word	NOUN
mkg-872	11	3	:	:	PUNCT
mkg-872	11	4	saliva	saliva	NOUN
mkg-872	11	5	,	,	PUNCT
mkg-872	11	6	diagnostic	diagnostic	ADJ
mkg-872	11	7	biomarker	biomarker	NOUN
mkg-872	11	8	,	,	PUNCT
mkg-872	11	9	periodontal	periodontal	ADJ
mkg-872	11	10	disease	disease	NOUN
mkg-872	11	11	abstrak	abstrak	PROPN
mkg-872	11	12	latar	latar	PROPN
mkg-872	11	13	belakang	belakang	PROPN
mkg-872	11	14	:	:	PUNCT
mkg-872	11	15	banyak	banyak	PROPN
mkg-872	11	16	biomarker	biomarker	PROPN
mkg-872	11	17	telah	telah	PROPN
mkg-872	11	18	ditemukan	ditemukan	PROPN
mkg-872	11	19	dalam	dalam	PROPN
mkg-872	11	20	saliva	saliva	PROPN
mkg-872	11	21	.	.	PUNCT
mkg-872	12	1	saliva	saliva	NOUN
mkg-872	12	2	terdiri	terdiri	PROPN
mkg-872	12	3	dari	dari	PROPN
mkg-872	12	4	berbagai	berbagai	PROPN
mkg-872	12	5	protein	protein	PROPN
mkg-872	12	6	unik	unik	PROPN
mkg-872	12	7	meliputi	meliputi	PROPN
mkg-872	12	8	bakteri	bakteri	PROPN
mkg-872	12	9	dan	dan	PROPN
mkg-872	12	10	produk	produk	PROPN
mkg-872	12	11	bakteri	bakteri	PROPN
mkg-872	12	12	,	,	PUNCT
mkg-872	12	13	enzim	enzim	PROPN
mkg-872	12	14	,	,	PUNCT
mkg-872	12	15	mediator	mediator	NOUN
mkg-872	12	16	inflamasi	inflamasi	PROPN
mkg-872	12	17	dan	dan	PROPN
mkg-872	12	18	modifikasi	modifikasi	PROPN
mkg-872	12	19	respon	respon	PROPN
mkg-872	12	20	host	host	NOUN
mkg-872	12	21	(	(	PUNCT
mkg-872	12	22	immunoglobulin	immunoglobulin	NOUN
mkg-872	12	23	,	,	PUNCT
mkg-872	12	24	sitokin	sitokin	ADJ
mkg-872	12	25	)	)	PUNCT
mkg-872	12	26	,	,	PUNCT
mkg-872	12	27	produk	produk	PROPN
mkg-872	12	28	kerusakan	kerusakan	PROPN
mkg-872	12	29	jaringan	jaringan	PROPN
mkg-872	12	30	(	(	PUNCT
mkg-872	12	31	telopeptida	telopeptida	PROPN
mkg-872	12	32	kolagen	kolagen	PROPN
mkg-872	12	33	,	,	PUNCT
mkg-872	12	34	osteokalsin	osteokalsin	PROPN
mkg-872	12	35	,	,	PUNCT
mkg-872	12	36	proteoglikan	proteoglikan	NOUN
mkg-872	12	37	,	,	PUNCT
mkg-872	12	38	fragmen	fragman	NOUN
mkg-872	12	39	fibronectin	fibronectin	NOUN
mkg-872	12	40	)	)	PUNCT
mkg-872	12	41	.	.	PUNCT
mkg-872	13	1	tujuan	tujuan	NOUN
mkg-872	13	2	:	:	PUNCT
mkg-872	14	1	mengkaji	mengkaji	VERB
mkg-872	14	2	biomarker	biomarker	NOUN
mkg-872	14	3	dalam	dalam	PROPN
mkg-872	14	4	saliva	saliva	PROPN
mkg-872	14	5	untuk	untuk	PROPN
mkg-872	14	6	pengembangan	pengembangan	PROPN
mkg-872	14	7	metode	metode	PROPN
mkg-872	14	8	diagnostik	diagnostik	PROPN
mkg-872	14	9	sederhana	sederhana	PROPN
mkg-872	14	10	dan	dan	PROPN
mkg-872	14	11	akurat	akurat	PROPN
mkg-872	14	12	untuk	untuk	PROPN
mkg-872	14	13	penyakit	penyakit	PROPN
mkg-872	14	14	periodontal	periodontal	PROPN
mkg-872	14	15	.	.	PUNCT
mkg-872	15	1	tinjauan	tinjauan	PROPN
mkg-872	15	2	pustaka	pustaka	ADV
mkg-872	15	3	:	:	PUNCT
mkg-872	16	1	secara	secara	PROPN
mkg-872	16	2	khusus	khusus	PROPN
mkg-872	16	3	,	,	PUNCT
mkg-872	16	4	biomarker	biomarker	NOUN
mkg-872	16	5	saliva	saliva	NOUN
mkg-872	16	6	pada	pada	PROPN
mkg-872	16	7	periodontitis	periodontitis	PROPN
mkg-872	16	8	dibagi	dibagi	PROPN
mkg-872	16	9	dalam	dalam	PROPN
mkg-872	16	10	tiga	tiga	PROPN
mkg-872	16	11	aspek	aspek	VERB
mkg-872	16	12	yaitu	yaitu	PROPN
mkg-872	16	13	inflamasi	inflamasi	PROPN
mkg-872	16	14	,	,	PUNCT
mkg-872	16	15	dan	dan	PROPN
mkg-872	16	16	degradasi	degradasi	PROPN
mkg-872	16	17	kolagen	kolagen	PROPN
mkg-872	16	18	serta	serta	PROPN
mkg-872	16	19	pergantian	pergantian	PROPN
mkg-872	16	20	tulang	tulang	PROPN
mkg-872	16	21	.	.	PUNCT
mkg-872	17	1	biomarker	biomarker	PROPN
mkg-872	17	2	diagnostik	diagnostik	NOUN
mkg-872	17	3	dalam	dalam	PROPN
mkg-872	17	4	saliva	saliva	NOUN
mkg-872	17	5	,	,	PUNCT
mkg-872	17	6	meliputi	meliputi	NOUN
mkg-872	17	7	enzim	enzim	PROPN
mkg-872	17	8	,	,	PUNCT
mkg-872	17	9	imunoglobulin	imunoglobulin	NOUN
mkg-872	17	10	,	,	PUNCT
mkg-872	17	11	sitokin	sitokin	ADJ
mkg-872	17	12	,	,	PUNCT
mkg-872	17	13	bakteri	bakteri	PROPN
mkg-872	17	14	dan	dan	PROPN
mkg-872	17	15	produk	produk	PROPN
mkg-872	17	16	-	-	PUNCT
mkg-872	17	17	produk	produk	PROPN
mkg-872	17	18	bakteri	bakteri	PROPN
mkg-872	17	19	,	,	PUNCT
mkg-872	17	20	hormon	hormon	PROPN
mkg-872	17	21	.	.	PUNCT
mkg-872	18	1	selama	selama	PROPN
mkg-872	18	2	dua	dua	PROPN
mkg-872	18	3	dekade	dekade	VERB
mkg-872	18	4	terakhir	terakhir	ADJ
mkg-872	18	5	,	,	PUNCT
mkg-872	18	6	para	para	PROPN
mkg-872	18	7	peneliti	peneliti	PROPN
mkg-872	18	8	kesehatan	kesehatan	PROPN
mkg-872	18	9	mulut	mulut	PROPN
mkg-872	18	10	telah	telah	PROPN
mkg-872	18	11	mengembangkan	mengembangkan	PROPN
mkg-872	18	12	alat	alat	PROPN
mkg-872	18	13	diagnostik	diagnostik	PROPN
mkg-872	18	14	melalui	melalui	PROPN
mkg-872	18	15	saliva	saliva	PROPN
mkg-872	18	16	yang	yang	PROPN
mkg-872	18	17	tepat	tepat	PROPN
mkg-872	18	18	untuk	untuk	PROPN
mkg-872	18	19	memonitor	memonitor	PROPN
mkg-872	18	20	beberapa	beberapa	PROPN
mkg-872	18	21	penyakit	penyakit	PROPN
mkg-872	18	22	periodontal	periodontal	PROPN
mkg-872	18	23	.	.	PUNCT
mkg-872	19	1	kesimpulan	kesimpulan	PROPN
mkg-872	19	2	:	:	PUNCT
mkg-872	20	1	indikator	indikator	NOUN
mkg-872	20	2	periodontitis	periodontitis	NOUN
mkg-872	20	3	akut	akut	PROPN
mkg-872	20	4	dapat	dapat	PROPN
mkg-872	20	5	dideteksi	dideteksi	PROPN
mkg-872	20	6	dengan	dengan	PROPN
mkg-872	20	7	β	β	PROPN
mkg-872	20	8	-	-	PROPN
mkg-872	20	9	glucuronidase	glucuronidase	PROPN
mkg-872	20	10	dan	dan	PROPN
mkg-872	20	11	ast	ast	PROPN
mkg-872	20	12	,	,	PUNCT
mkg-872	20	13	il-1β	il-1β	PROPN
mkg-872	20	14	,	,	PUNCT
mkg-872	20	15	dan	dan	PROPN
mkg-872	20	16	mmp-8	mmp-8	ADV
mkg-872	20	17	,	,	PUNCT
mkg-872	20	18	whereas	whereas	SCONJ
mkg-872	20	19	indikator	indikator	NOUN
mkg-872	20	20	untuk	untuk	NOUN
mkg-872	20	21	periodontitis	periodontitis	PROPN
mkg-872	20	22	kronis	kronis	PROPN
mkg-872	20	23	dapat	dapat	PROPN
mkg-872	20	24	dideteksi	dideteksi	PROPN
mkg-872	20	25	dengan	dengan	PROPN
mkg-872	20	26	alp	alp	PROPN
mkg-872	20	27	.	.	PUNCT
mkg-872	20	28	indikator	indikator	PROPN
mkg-872	20	29	untuk	untuk	PROPN
mkg-872	20	30	degradasi	degradasi	PROPN
mkg-872	20	31	kolagen	kolagen	PROPN
mkg-872	20	32	dan	dan	PROPN
mkg-872	20	33	penggantian	penggantian	PROPN
mkg-872	20	34	tulang	tulang	PROPN
mkg-872	20	35	dideteksi	dideteksi	PROPN
mkg-872	20	36	melalui	melalui	PROPN
mkg-872	20	37	ictp	ictp	PROPN
mkg-872	20	38	,	,	PUNCT
mkg-872	20	39	fibronectin	fibronectin	NOUN
mkg-872	20	40	fragments	fragment	NOUN
mkg-872	20	41	,	,	PUNCT
mkg-872	20	42	dan	dan	PROPN
mkg-872	20	43	osteonectin	osteonectin	PROPN
mkg-872	20	44	.	.	PUNCT
mkg-872	21	1	sedang	sedang	PROPN
mkg-872	21	2	indikator	indikator	PROPN
mkg-872	21	3	untuk	untuk	PROPN
mkg-872	21	4	keparahan	keparahan	PROPN
mkg-872	21	5	periodontitis	periodontitis	PROPN
mkg-872	21	6	terutama	terutama	PROPN
mkg-872	22	1	dapat	dapat	PROPN
mkg-872	22	2	diprediksi	diprediksi	PROPN
mkg-872	22	3	melalui	melalui	PROPN
mkg-872	22	4	b.	b.	PROPN
mkg-872	22	5	forsythus	forsythus	PROPN
mkg-872	22	6	.	.	PUNCT
mkg-872	23	1	kata	kata	PROPN
mkg-872	23	2	kunci	kunci	PROPN
mkg-872	23	3	:	:	PUNCT
mkg-872	23	4	saliva	saliva	NOUN
mkg-872	23	5	,	,	PUNCT
mkg-872	23	6	biomarker	biomarker	NOUN
mkg-872	23	7	diagnostik	diagnostik	NOUN
mkg-872	23	8	,	,	PUNCT
mkg-872	23	9	penyakit	penyakit	PROPN
mkg-872	23	10	periodontal	periodontal	ADJ
mkg-872	23	11	correspondence	correspondence	NOUN
mkg-872	23	12	:	:	PUNCT
mkg-872	23	13	zahreni	zahreni	NOUN
mkg-872	23	14	-	-	PUNCT
mkg-872	23	15	hamzah	hamzah	PROPN
mkg-872	23	16	,	,	PUNCT
mkg-872	23	17	c	c	X
mkg-872	23	18	/	/	SYM
mkg-872	23	19	o	o	NOUN
mkg-872	23	20	:	:	PUNCT
mkg-872	23	21	laboratorium	laboratorium	NOUN
mkg-872	23	22	biomedik	biomedik	PROPN
mkg-872	23	23	,	,	PUNCT
mkg-872	23	24	fakultas	fakulta	VERB
mkg-872	23	25	kedokteran	kedokteran	PROPN
mkg-872	23	26	gigi	gigi	PROPN
mkg-872	23	27	universitas	universitas	PROPN
mkg-872	23	28	jember	jember	PROPN
mkg-872	23	29	.	.	PUNCT
mkg-872	24	1	jl	jl	PROPN
mkg-872	24	2	.	.	PROPN
mkg-872	24	3	kalimantan	kalimantan	PROPN
mkg-872	24	4	37	37	NUM
mkg-872	24	5	jember	jember	PROPN
mkg-872	24	6	68121	68121	NUM
mkg-872	24	7	,	,	PUNCT
mkg-872	24	8	indonesia	indonesia	PROPN
mkg-872	24	9	.	.	PUNCT
mkg-872	25	1	e	e	X
mkg-872	25	2	-	-	NOUN
mkg-872	25	3	mail	mail	NOUN
mkg-872	25	4	:	:	PUNCT
mkg-872	25	5	reni61_hamzah@yahoo.co.id	reni61_hamzah@yahoo.co.id	PROPN
mkg-872	25	6	literature	literature	PROPN
mkg-872	25	7	review	review	PROPN
mkg-872	25	8	introduction	introduction	NOUN
mkg-872	25	9	periodontitis	periodontitis	NOUN
mkg-872	25	10	is	be	AUX
mkg-872	25	11	a	a	DET
mkg-872	25	12	chronic	chronic	ADJ
mkg-872	25	13	destructive	destructive	ADJ
mkg-872	25	14	category	category	NOUN
mkg-872	25	15	of	of	ADP
mkg-872	25	16	periodontal	periodontal	ADJ
mkg-872	25	17	disease	disease	NOUN
mkg-872	25	18	that	that	PRON
mkg-872	25	19	progresses	progress	VERB
mkg-872	25	20	to	to	ADP
mkg-872	25	21	the	the	DET
mkg-872	25	22	resorption	resorption	NOUN
mkg-872	25	23	of	of	ADP
mkg-872	25	24	alveolar	alveolar	ADJ
mkg-872	25	25	bone	bone	NOUN
mkg-872	25	26	,	,	PUNCT
mkg-872	25	27	which	which	PRON
mkg-872	25	28	leads	lead	VERB
mkg-872	25	29	to	to	ADP
mkg-872	25	30	progressive	progressive	ADJ
mkg-872	25	31	bone	bone	NOUN
mkg-872	25	32	destruction	destruction	NOUN
mkg-872	25	33	and	and	CCONJ
mkg-872	25	34	tooth	tooth	NOUN
mkg-872	25	35	loss	loss	NOUN
mkg-872	25	36	.	.	PUNCT
mkg-872	26	1	as	as	ADP
mkg-872	26	2	a	a	DET
mkg-872	26	3	consequence	consequence	NOUN
mkg-872	26	4	of	of	ADP
mkg-872	26	5	resorption	resorption	NOUN
mkg-872	26	6	,	,	PUNCT
mkg-872	26	7	breakdown	breakdown	NOUN
mkg-872	26	8	of	of	ADP
mkg-872	26	9	products	product	NOUN
mkg-872	26	10	are	be	AUX
mkg-872	26	11	released	release	VERB
mkg-872	26	12	into	into	ADP
mkg-872	26	13	periodontal	periodontal	ADJ
mkg-872	26	14	tissues	tissue	NOUN
mkg-872	26	15	,	,	PUNCT
mkg-872	26	16	migrating	migrate	VERB
mkg-872	26	17	toward	toward	ADP
mkg-872	26	18	the	the	DET
mkg-872	26	19	gingival	gingival	NOUN
mkg-872	26	20	sulcus	sulcus	NOUN
mkg-872	26	21	and	and	CCONJ
mkg-872	26	22	gathering	gather	VERB
mkg-872	26	23	from	from	ADP
mkg-872	26	24	the	the	DET
mkg-872	26	25	78	78	NUM
mkg-872	26	26	dent	dent	NOUN
mkg-872	26	27	.	.	PUNCT
mkg-872	27	1	j.	j.	PROPN
mkg-872	27	2	(	(	PUNCT
mkg-872	27	3	maj	maj	PROPN
mkg-872	27	4	.	.	PROPN
mkg-872	27	5	ked	ked	PROPN
mkg-872	27	6	.	.	PUNCT
mkg-872	28	1	gigi	gigi	PROPN
mkg-872	28	2	)	)	PUNCT
mkg-872	28	3	,	,	PUNCT
mkg-872	29	1	vol	vol	NOUN
mkg-872	29	2	.	.	PROPN
mkg-872	29	3	44	44	NUM
mkg-872	29	4	.	.	PUNCT
mkg-872	30	1	no	no	INTJ
mkg-872	30	2	.	.	NOUN
mkg-872	31	1	2	2	NUM
mkg-872	31	2	june	june	PROPN
mkg-872	31	3	2011	2011	NUM
mkg-872	31	4	:	:	PUNCT
mkg-872	31	5	77–81	77–81	NUM
mkg-872	31	6	surrounding	surround	VERB
mkg-872	31	7	site	site	NOUN
mkg-872	31	8	in	in	ADP
mkg-872	31	9	whole	whole	ADJ
mkg-872	31	10	saliva	saliva	NOUN
mkg-872	31	11	,	,	PUNCT
mkg-872	31	12	where	where	SCONJ
mkg-872	31	13	several	several	ADJ
mkg-872	31	14	of	of	ADP
mkg-872	31	15	them	they	PRON
mkg-872	31	16	have	have	AUX
mkg-872	31	17	been	be	AUX
mkg-872	31	18	identified	identify	VERB
mkg-872	31	19	.	.	PUNCT
mkg-872	32	1	several	several	ADJ
mkg-872	32	2	important	important	ADJ
mkg-872	32	3	components	component	NOUN
mkg-872	32	4	of	of	ADP
mkg-872	32	5	saliva	saliva	NOUN
mkg-872	32	6	that	that	PRON
mkg-872	32	7	can	can	AUX
mkg-872	32	8	be	be	AUX
mkg-872	32	9	used	use	VERB
mkg-872	32	10	as	as	ADP
mkg-872	32	11	indicators	indicator	NOUN
mkg-872	32	12	of	of	ADP
mkg-872	32	13	periodontal	periodontal	ADJ
mkg-872	32	14	disease	disease	NOUN
mkg-872	32	15	are	be	AUX
mkg-872	32	16	microbial	microbial	ADJ
mkg-872	32	17	factors	factor	NOUN
mkg-872	32	18	,	,	PUNCT
mkg-872	32	19	host	host	NOUN
mkg-872	32	20	derived	derive	VERB
mkg-872	32	21	enzymes	enzyme	NOUN
mkg-872	32	22	,	,	PUNCT
mkg-872	32	23	inflammatory	inflammatory	ADJ
mkg-872	32	24	mediators	mediator	NOUN
mkg-872	32	25	and	and	CCONJ
mkg-872	32	26	host	host	NOUN
mkg-872	32	27	response	response	NOUN
mkg-872	32	28	modifiers	modifier	NOUN
mkg-872	32	29	,	,	PUNCT
mkg-872	32	30	and	and	CCONJ
mkg-872	32	31	products	product	NOUN
mkg-872	32	32	of	of	ADP
mkg-872	32	33	tissue	tissue	NOUN
mkg-872	32	34	breakdown.1–8	breakdown.1–8	NOUN
mkg-872	32	35	recently	recently	ADV
mkg-872	32	36	,	,	PUNCT
mkg-872	32	37	saliva	saliva	NOUN
mkg-872	32	38	has	have	AUX
mkg-872	32	39	been	be	AUX
mkg-872	32	40	studied	study	VERB
mkg-872	32	41	as	as	ADP
mkg-872	32	42	an	an	DET
mkg-872	32	43	important	important	ADJ
mkg-872	32	44	biological	biological	ADJ
mkg-872	32	45	marker	marker	NOUN
mkg-872	32	46	for	for	ADP
mkg-872	32	47	introducing	introduce	VERB
mkg-872	32	48	new	new	ADJ
mkg-872	32	49	diagnostic	diagnostic	ADJ
mkg-872	32	50	tests	test	NOUN
mkg-872	32	51	that	that	PRON
mkg-872	32	52	can	can	AUX
mkg-872	32	53	contribute	contribute	VERB
mkg-872	32	54	to	to	ADP
mkg-872	32	55	making	make	VERB
mkg-872	32	56	the	the	DET
mkg-872	32	57	accurate	accurate	ADJ
mkg-872	32	58	diagnosis	diagnosis	NOUN
mkg-872	32	59	to	to	PART
mkg-872	32	60	explain	explain	VERB
mkg-872	32	61	the	the	DET
mkg-872	32	62	pathogenesis	pathogenesis	NOUN
mkg-872	32	63	of	of	ADP
mkg-872	32	64	a	a	DET
mkg-872	32	65	disease	disease	NOUN
mkg-872	32	66	.	.	PUNCT
mkg-872	33	1	there	there	PRON
mkg-872	33	2	was	be	VERB
mkg-872	33	3	many	many	ADJ
mkg-872	33	4	biomarkers	biomarker	NOUN
mkg-872	33	5	of	of	ADP
mkg-872	33	6	periodontal	periodontal	ADJ
mkg-872	33	7	diseases	disease	NOUN
mkg-872	33	8	have	have	AUX
mkg-872	33	9	found	find	VERB
mkg-872	33	10	in	in	ADP
mkg-872	33	11	saliva.2–5	saliva.2–5	NOUN
mkg-872	33	12	over	over	ADP
mkg-872	33	13	the	the	DET
mkg-872	33	14	last	last	ADJ
mkg-872	33	15	two	two	NUM
mkg-872	33	16	decades	decade	NOUN
mkg-872	33	17	,	,	PUNCT
mkg-872	33	18	researchers	researcher	NOUN
mkg-872	33	19	in	in	ADP
mkg-872	33	20	the	the	DET
mkg-872	33	21	oral	oral	ADJ
mkg-872	33	22	health	health	NOUN
mkg-872	33	23	have	have	AUX
mkg-872	33	24	been	be	AUX
mkg-872	33	25	trying	try	VERB
mkg-872	33	26	to	to	PART
mkg-872	33	27	develop	develop	VERB
mkg-872	33	28	a	a	DET
mkg-872	33	29	diagnostic	diagnostic	ADJ
mkg-872	33	30	tool	tool	NOUN
mkg-872	33	31	to	to	PART
mkg-872	33	32	use	use	VERB
mkg-872	33	33	saliva	saliva	NOUN
mkg-872	33	34	to	to	PART
mkg-872	33	35	monitor	monitor	VERB
mkg-872	33	36	various	various	ADJ
mkg-872	33	37	periodontal	periodontal	ADJ
mkg-872	33	38	diseases.6,8	diseases.6,8	NOUN
mkg-872	33	39	the	the	DET
mkg-872	33	40	development	development	NOUN
mkg-872	33	41	of	of	ADP
mkg-872	33	42	salivary	salivary	ADJ
mkg-872	33	43	diagnostic	diagnostic	ADJ
mkg-872	33	44	technology	technology	NOUN
mkg-872	33	45	currently	currently	ADV
mkg-872	33	46	leads	lead	VERB
mkg-872	33	47	the	the	DET
mkg-872	33	48	development	development	NOUN
mkg-872	33	49	of	of	ADP
mkg-872	33	50	diagnostic	diagnostic	ADJ
mkg-872	33	51	tools	tool	NOUN
mkg-872	33	52	that	that	PRON
mkg-872	33	53	simply	simply	ADV
mkg-872	33	54	,	,	PUNCT
mkg-872	33	55	quickly	quickly	ADV
mkg-872	33	56	and	and	CCONJ
mkg-872	33	57	accurately	accurately	ADV
mkg-872	33	58	to	to	PART
mkg-872	33	59	facilitate	facilitate	VERB
mkg-872	33	60	the	the	DET
mkg-872	33	61	dentists	dentist	NOUN
mkg-872	33	62	in	in	ADP
mkg-872	33	63	making	make	VERB
mkg-872	33	64	clinical	clinical	ADJ
mkg-872	33	65	decisions	decision	NOUN
mkg-872	33	66	and	and	CCONJ
mkg-872	33	67	predict	predict	VERB
mkg-872	33	68	the	the	DET
mkg-872	33	69	outcome	outcome	NOUN
mkg-872	33	70	of	of	ADP
mkg-872	33	71	treatment	treatment	NOUN
mkg-872	33	72	in	in	ADP
mkg-872	33	73	the	the	DET
mkg-872	33	74	oral	oral	ADJ
mkg-872	33	75	cavity	cavity	NOUN
mkg-872	33	76	,	,	PUNCT
mkg-872	33	77	including	include	VERB
mkg-872	33	78	the	the	DET
mkg-872	33	79	diseases	disease	NOUN
mkg-872	33	80	related	relate	VERB
mkg-872	33	81	to	to	ADP
mkg-872	33	82	the	the	DET
mkg-872	33	83	general	general	ADJ
mkg-872	33	84	health	health	NOUN
mkg-872	33	85	.	.	PUNCT
mkg-872	34	1	considering	consider	VERB
mkg-872	34	2	the	the	DET
mkg-872	34	3	exchange	exchange	NOUN
mkg-872	34	4	activity	activity	NOUN
mkg-872	34	5	of	of	ADP
mkg-872	34	6	extra	extra	ADJ
mkg-872	34	7	cellular	cellular	ADJ
mkg-872	34	8	fluid	fluid	NOUN
mkg-872	34	9	and	and	CCONJ
mkg-872	34	10	saliva	saliva	NOUN
mkg-872	34	11	is	be	AUX
mkg-872	34	12	high	high	ADJ
mkg-872	34	13	,	,	PUNCT
mkg-872	34	14	so	so	ADV
mkg-872	34	15	its	its	PRON
mkg-872	34	16	allow	allow	VERB
mkg-872	34	17	the	the	DET
mkg-872	34	18	compounds	compound	NOUN
mkg-872	34	19	that	that	PRON
mkg-872	34	20	important	important	ADJ
mkg-872	34	21	as	as	ADP
mkg-872	34	22	an	an	DET
mkg-872	34	23	indicators	indicator	NOUN
mkg-872	34	24	of	of	ADP
mkg-872	34	25	disease	disease	NOUN
mkg-872	34	26	associated	associate	VERB
mkg-872	34	27	with	with	ADP
mkg-872	34	28	general	general	ADJ
mkg-872	34	29	health	health	NOUN
mkg-872	34	30	can	can	AUX
mkg-872	34	31	be	be	AUX
mkg-872	34	32	found	find	VERB
mkg-872	34	33	also	also	ADV
mkg-872	34	34	in	in	ADV
mkg-872	34	35	saliva.1,8,9	saliva.1,8,9	ADP
mkg-872	34	36	furthermore	furthermore	ADV
mkg-872	34	37	,	,	PUNCT
mkg-872	34	38	the	the	DET
mkg-872	34	39	dentist	dentist	NOUN
mkg-872	34	40	expected	expect	VERB
mkg-872	34	41	to	to	PART
mkg-872	34	42	be	be	AUX
mkg-872	34	43	the	the	DET
mkg-872	34	44	first	first	ADJ
mkg-872	34	45	person	person	NOUN
mkg-872	34	46	to	to	PART
mkg-872	34	47	recognize	recognize	VERB
mkg-872	34	48	the	the	DET
mkg-872	34	49	oral	oral	ADJ
mkg-872	34	50	disease	disease	NOUN
mkg-872	34	51	and	and	CCONJ
mkg-872	34	52	the	the	DET
mkg-872	34	53	other	other	ADJ
mkg-872	34	54	general	general	ADJ
mkg-872	34	55	disease	disease	NOUN
mkg-872	34	56	.	.	PUNCT
mkg-872	35	1	the	the	DET
mkg-872	35	2	salivary	salivary	ADJ
mkg-872	35	3	biomarkers	biomarker	NOUN
mkg-872	35	4	specific	specific	ADJ
mkg-872	35	5	that	that	PRON
mkg-872	35	6	correlated	correlate	VERB
mkg-872	35	7	with	with	ADP
mkg-872	35	8	clinical	clinical	ADJ
mkg-872	35	9	features	feature	NOUN
mkg-872	35	10	of	of	ADP
mkg-872	35	11	periodontal	periodontal	ADJ
mkg-872	35	12	disease	disease	NOUN
mkg-872	35	13	can	can	AUX
mkg-872	35	14	determine	determine	VERB
mkg-872	35	15	by	by	ADP
mkg-872	35	16	three	three	NUM
mkg-872	35	17	aspects	aspect	NOUN
mkg-872	35	18	:	:	PUNCT
mkg-872	35	19	inflammation	inflammation	NOUN
mkg-872	35	20	,	,	PUNCT
mkg-872	35	21	collagen	collagen	NOUN
mkg-872	35	22	degradation	degradation	NOUN
mkg-872	35	23	,	,	PUNCT
mkg-872	35	24	and	and	CCONJ
mkg-872	35	25	bone	bone	NOUN
mkg-872	35	26	turnover.3,10	turnover.3,10	NOUN
mkg-872	35	27	the	the	DET
mkg-872	35	28	purpose	purpose	NOUN
mkg-872	35	29	of	of	ADP
mkg-872	35	30	the	the	DET
mkg-872	35	31	study	study	NOUN
mkg-872	35	32	was	be	AUX
mkg-872	35	33	to	to	PART
mkg-872	35	34	studied	study	VERB
mkg-872	35	35	current	current	ADJ
mkg-872	35	36	development	development	NOUN
mkg-872	35	37	of	of	ADP
mkg-872	35	38	diagnostic	diagnostic	ADJ
mkg-872	35	39	biomarkers	biomarker	NOUN
mkg-872	35	40	in	in	ADP
mkg-872	35	41	saliva	saliva	NOUN
mkg-872	35	42	that	that	PRON
mkg-872	35	43	will	will	AUX
mkg-872	35	44	lead	lead	VERB
mkg-872	35	45	to	to	ADP
mkg-872	35	46	the	the	DET
mkg-872	35	47	development	development	NOUN
mkg-872	35	48	of	of	ADP
mkg-872	35	49	simple	simple	ADJ
mkg-872	35	50	and	and	CCONJ
mkg-872	35	51	accurate	accurate	ADJ
mkg-872	35	52	diagnostic	diagnostic	ADJ
mkg-872	35	53	tools	tool	NOUN
mkg-872	35	54	for	for	ADP
mkg-872	35	55	periodontal	periodontal	ADJ
mkg-872	35	56	disease	disease	NOUN
mkg-872	35	57	.	.	PUNCT
mkg-872	36	1	it	it	PRON
mkg-872	36	2	can	can	AUX
mkg-872	36	3	use	use	VERB
mkg-872	36	4	to	to	PART
mkg-872	36	5	make	make	VERB
mkg-872	36	6	clinical	clinical	ADJ
mkg-872	36	7	decisions	decision	NOUN
mkg-872	36	8	and	and	CCONJ
mkg-872	36	9	predict	predict	VERB
mkg-872	36	10	the	the	DET
mkg-872	36	11	outcome	outcome	NOUN
mkg-872	36	12	of	of	ADP
mkg-872	36	13	treatment	treatment	NOUN
mkg-872	36	14	in	in	ADP
mkg-872	36	15	the	the	DET
mkg-872	36	16	oral	oral	ADJ
mkg-872	36	17	cavity	cavity	NOUN
mkg-872	36	18	,	,	PUNCT
mkg-872	36	19	including	include	VERB
mkg-872	36	20	diseases	disease	NOUN
mkg-872	36	21	related	relate	VERB
mkg-872	36	22	to	to	ADP
mkg-872	36	23	the	the	DET
mkg-872	36	24	general	general	ADJ
mkg-872	36	25	health	health	NOUN
mkg-872	36	26	.	.	PUNCT
mkg-872	37	1	periodontal	periodontal	ADJ
mkg-872	37	2	inflammation	inflammation	ADJ
mkg-872	37	3	periodontal	periodontal	ADJ
mkg-872	37	4	diseases	disease	NOUN
mkg-872	37	5	are	be	AUX
mkg-872	37	6	further	far	ADV
mkg-872	37	7	divided	divide	VERB
mkg-872	37	8	into	into	ADP
mkg-872	37	9	reversible	reversible	ADJ
mkg-872	37	10	and	and	CCONJ
mkg-872	37	11	nonreversible	nonreversible	ADJ
mkg-872	37	12	categories	category	NOUN
mkg-872	37	13	.	.	PUNCT
mkg-872	38	1	gingivitis	gingivitis	NOUN
mkg-872	38	2	is	be	AUX
mkg-872	38	3	a	a	DET
mkg-872	38	4	reversible	reversible	ADJ
mkg-872	38	5	infl	infl	NOUN
mkg-872	38	6	ammatory	ammatory	NOUN
mkg-872	38	7	reaction	reaction	NOUN
mkg-872	38	8	of	of	ADP
mkg-872	38	9	the	the	DET
mkg-872	38	10	marginal	marginal	ADJ
mkg-872	38	11	gingiva	gingiva	NOUN
mkg-872	38	12	to	to	ADP
mkg-872	38	13	dental	dental	ADJ
mkg-872	38	14	plaque	plaque	NOUN
mkg-872	38	15	biofi	biofi	NOUN
mkg-872	38	16	lms	lm	NOUN
mkg-872	38	17	.	.	PUNCT
mkg-872	39	1	gingivitis	gingivitis	NOUN
mkg-872	39	2	is	be	AUX
mkg-872	39	3	characterized	characterize	VERB
mkg-872	39	4	by	by	ADP
mkg-872	39	5	an	an	DET
mkg-872	39	6	initial	initial	ADJ
mkg-872	39	7	increase	increase	NOUN
mkg-872	39	8	in	in	ADP
mkg-872	39	9	blood	blood	NOUN
mkg-872	39	10	fl	fl	ADP
mkg-872	39	11	ow	ow	PROPN
mkg-872	39	12	,	,	PUNCT
mkg-872	39	13	enhanced	enhance	VERB
mkg-872	39	14	vascular	vascular	ADJ
mkg-872	39	15	permeability	permeability	NOUN
mkg-872	39	16	,	,	PUNCT
mkg-872	39	17	and	and	CCONJ
mkg-872	39	18	infl	infl	PROPN
mkg-872	39	19	ux	ux	PROPN
mkg-872	39	20	of	of	ADP
mkg-872	39	21	cells	cell	NOUN
mkg-872	39	22	(	(	PUNCT
mkg-872	39	23	polymorphonuclear	polymorphonuclear	NOUN
mkg-872	39	24	leukocytes	leukocyte	VERB
mkg-872	39	25	[	[	X
mkg-872	39	26	pmns	pmn	NOUN
mkg-872	39	27	]	]	X
mkg-872	39	28	and	and	CCONJ
mkg-872	39	29	monocyte	monocyte	NOUN
mkg-872	39	30	-	-	PUNCT
mkg-872	39	31	macrophages	macrophage	NOUN
mkg-872	39	32	)	)	PUNCT
mkg-872	39	33	from	from	ADP
mkg-872	39	34	the	the	DET
mkg-872	39	35	peripheral	peripheral	ADJ
mkg-872	39	36	blood	blood	NOUN
mkg-872	39	37	into	into	ADP
mkg-872	39	38	the	the	DET
mkg-872	39	39	periodontal	periodontal	ADJ
mkg-872	39	40	connective	connective	ADJ
mkg-872	39	41	tissue	tissue	NOUN
mkg-872	39	42	.	.	PUNCT
mkg-872	40	1	overt	overt	ADJ
mkg-872	40	2	soft	soft	ADJ
mkg-872	40	3	tissue	tissue	NOUN
mkg-872	40	4	alterations	alteration	NOUN
mkg-872	40	5	during	during	ADP
mkg-872	40	6	the	the	DET
mkg-872	40	7	state	state	NOUN
mkg-872	40	8	of	of	ADP
mkg-872	40	9	gingivitis	gingivitis	NOUN
mkg-872	40	10	include	include	VERB
mkg-872	40	11	redness	redness	NOUN
mkg-872	40	12	,	,	PUNCT
mkg-872	40	13	edema	edema	NOUN
mkg-872	40	14	,	,	PUNCT
mkg-872	40	15	bleeding	bleeding	NOUN
mkg-872	40	16	,	,	PUNCT
mkg-872	40	17	and	and	CCONJ
mkg-872	40	18	tenderness	tenderness	NOUN
mkg-872	40	19	.	.	PUNCT
mkg-872	41	1	whereas	whereas	SCONJ
mkg-872	41	2	,	,	PUNCT
mkg-872	41	3	periodontitis	periodontitis	NOUN
mkg-872	41	4	is	be	AUX
mkg-872	41	5	the	the	DET
mkg-872	41	6	destructive	destructive	ADJ
mkg-872	41	7	category	category	NOUN
mkg-872	41	8	of	of	ADP
mkg-872	41	9	periodontal	periodontal	ADJ
mkg-872	41	10	disease	disease	NOUN
mkg-872	41	11	,	,	PUNCT
mkg-872	41	12	is	be	AUX
mkg-872	41	13	a	a	DET
mkg-872	41	14	nonreversible	nonreversible	ADJ
mkg-872	41	15	inflammatory	inflammatory	ADJ
mkg-872	41	16	state	state	NOUN
mkg-872	41	17	of	of	ADP
mkg-872	41	18	the	the	DET
mkg-872	41	19	supporting	support	VERB
mkg-872	41	20	structures	structure	NOUN
mkg-872	41	21	.	.	PUNCT
mkg-872	42	1	after	after	ADP
mkg-872	42	2	its	its	PRON
mkg-872	42	3	initiation	initiation	NOUN
mkg-872	42	4	,	,	PUNCT
mkg-872	42	5	the	the	DET
mkg-872	42	6	disease	disease	NOUN
mkg-872	42	7	progresses	progress	VERB
mkg-872	42	8	with	with	ADP
mkg-872	42	9	the	the	DET
mkg-872	42	10	loss	loss	NOUN
mkg-872	42	11	of	of	ADP
mkg-872	42	12	collagen	collagen	NOUN
mkg-872	42	13	fi	fi	NOUN
mkg-872	42	14	bers	ber	NOUN
mkg-872	42	15	and	and	CCONJ
mkg-872	42	16	attachment	attachment	NOUN
mkg-872	42	17	to	to	ADP
mkg-872	42	18	the	the	DET
mkg-872	42	19	cemental	cemental	ADJ
mkg-872	42	20	surface	surface	NOUN
mkg-872	42	21	,	,	PUNCT
mkg-872	42	22	apical	apical	ADJ
mkg-872	42	23	migration	migration	NOUN
mkg-872	42	24	of	of	ADP
mkg-872	42	25	the	the	DET
mkg-872	42	26	pocket	pocket	NOUN
mkg-872	42	27	epithelium	epithelium	NOUN
mkg-872	42	28	,	,	PUNCT
mkg-872	42	29	formation	formation	NOUN
mkg-872	42	30	of	of	ADP
mkg-872	42	31	deepened	deepen	VERB
mkg-872	42	32	periodontal	periodontal	ADJ
mkg-872	42	33	pockets	pocket	NOUN
mkg-872	42	34	,	,	PUNCT
mkg-872	42	35	and	and	CCONJ
mkg-872	42	36	the	the	DET
mkg-872	42	37	resorption	resorption	NOUN
mkg-872	42	38	of	of	ADP
mkg-872	42	39	alveolar	alveolar	ADJ
mkg-872	42	40	bone.11	bone.11	ADJ
mkg-872	42	41	recent	recent	ADJ
mkg-872	42	42	studies	study	NOUN
mkg-872	42	43	have	have	AUX
mkg-872	42	44	indicated	indicate	VERB
mkg-872	42	45	that	that	SCONJ
mkg-872	42	46	host	host	NOUN
mkg-872	42	47	response	response	NOUN
mkg-872	42	48	factors	factor	NOUN
mkg-872	42	49	to	to	ADP
mkg-872	42	50	infl	infl	PROPN
mkg-872	42	51	ammation	ammation	NOUN
mkg-872	42	52	and	and	CCONJ
mkg-872	42	53	periodontal	periodontal	ADJ
mkg-872	42	54	diseases	disease	NOUN
mkg-872	42	55	includes	include	VERB
mkg-872	42	56	a	a	DET
mkg-872	42	57	mixture	mixture	NOUN
mkg-872	42	58	of	of	ADP
mkg-872	42	59	molecules	molecule	NOUN
mkg-872	42	60	from	from	ADP
mkg-872	42	61	blood	blood	NOUN
mkg-872	42	62	,	,	PUNCT
mkg-872	42	63	host	host	NOUN
mkg-872	42	64	tissue	tissue	NOUN
mkg-872	42	65	,	,	PUNCT
mkg-872	42	66	plaque	plaque	NOUN
mkg-872	42	67	films	film	NOUN
mkg-872	42	68	,	,	PUNCT
mkg-872	42	69	such	such	ADJ
mkg-872	42	70	as	as	ADP
mkg-872	42	71	electrolytes	electrolyte	NOUN
mkg-872	42	72	,	,	PUNCT
mkg-872	42	73	small	small	ADJ
mkg-872	42	74	molecules	molecule	NOUN
mkg-872	42	75	,	,	PUNCT
mkg-872	42	76	proteins	protein	NOUN
mkg-872	42	77	,	,	PUNCT
mkg-872	42	78	cytokines	cytokine	NOUN
mkg-872	42	79	,	,	PUNCT
mkg-872	42	80	antibodies	antibodie	VERB
mkg-872	42	81	,	,	PUNCT
mkg-872	42	82	bacterial	bacterial	ADJ
mkg-872	42	83	and	and	CCONJ
mkg-872	42	84	product	product	NOUN
mkg-872	42	85	bacterial	bacterial	ADJ
mkg-872	42	86	antigens	antigen	NOUN
mkg-872	42	87	and	and	CCONJ
mkg-872	42	88	enzymes	enzyme	NOUN
mkg-872	42	89	.	.	PUNCT
mkg-872	43	1	the	the	DET
mkg-872	43	2	number	number	NOUN
mkg-872	43	3	and	and	CCONJ
mkg-872	43	4	various	various	ADJ
mkg-872	43	5	of	of	ADP
mkg-872	43	6	the	the	DET
mkg-872	43	7	materials	material	NOUN
mkg-872	43	8	that	that	PRON
mkg-872	43	9	present	present	VERB
mkg-872	43	10	in	in	ADP
mkg-872	43	11	saliva	saliva	NOUN
mkg-872	43	12	differ	differ	VERB
mkg-872	43	13	in	in	ADP
mkg-872	43	14	different	different	ADJ
mkg-872	43	15	types	type	NOUN
mkg-872	43	16	of	of	ADP
mkg-872	43	17	periodontal	periodontal	ADJ
mkg-872	43	18	disease	disease	NOUN
mkg-872	43	19	.	.	PUNCT
mkg-872	44	1	until	until	ADP
mkg-872	44	2	now	now	ADV
mkg-872	44	3	,	,	PUNCT
mkg-872	44	4	the	the	DET
mkg-872	44	5	number	number	NOUN
mkg-872	44	6	of	of	ADP
mkg-872	44	7	markers	marker	NOUN
mkg-872	44	8	analyzed	analyze	VERB
mkg-872	44	9	was	be	AUX
mkg-872	44	10	limited	limit	VERB
mkg-872	44	11	.	.	PUNCT
mkg-872	45	1	edentulous	edentulous	ADJ
mkg-872	45	2	persons	person	NOUN
mkg-872	45	3	and	and	CCONJ
mkg-872	45	4	chronic	chronic	ADJ
mkg-872	45	5	periodontitis	periodontitis	NOUN
mkg-872	45	6	persons	person	NOUN
mkg-872	45	7	have	have	AUX
mkg-872	45	8	reduced	reduce	VERB
mkg-872	45	9	salivary	salivary	ADJ
mkg-872	45	10	concentrations	concentration	NOUN
mkg-872	45	11	of	of	ADP
mkg-872	45	12	host	host	NOUN
mkg-872	45	13	infl	infl	PROPN
mkg-872	45	14	ammatory	ammatory	NOUN
mkg-872	45	15	proteins	protein	NOUN
mkg-872	45	16	.	.	PUNCT
mkg-872	46	1	these	these	DET
mkg-872	46	2	fi	fi	NOUN
mkg-872	46	3	ndings	nding	NOUN
mkg-872	46	4	suggest	suggest	VERB
mkg-872	46	5	that	that	SCONJ
mkg-872	46	6	a	a	DET
mkg-872	46	7	reduction	reduction	NOUN
mkg-872	46	8	in	in	ADP
mkg-872	46	9	host	host	NOUN
mkg-872	46	10	responsiveness	responsiveness	NOUN
mkg-872	46	11	might	might	AUX
mkg-872	46	12	play	play	VERB
mkg-872	46	13	a	a	DET
mkg-872	46	14	role	role	NOUN
mkg-872	46	15	in	in	ADP
mkg-872	46	16	the	the	DET
mkg-872	46	17	pathogenesis	pathogenesis	NOUN
mkg-872	46	18	of	of	ADP
mkg-872	46	19	chronic	chronic	ADJ
mkg-872	46	20	periodontitis.3,10,12	periodontitis.3,10,12	NOUN
mkg-872	46	21	salivary	salivary	VERB
mkg-872	46	22	indicator	indicator	NOUN
mkg-872	46	23	of	of	ADP
mkg-872	46	24	periodontal	periodontal	ADJ
mkg-872	46	25	inflammation	inflammation	NOUN
mkg-872	46	26	is	be	AUX
mkg-872	46	27	cytokines	cytokine	NOUN
mkg-872	46	28	.	.	PUNCT
mkg-872	47	1	the	the	DET
mkg-872	47	2	concentrations	concentration	NOUN
mkg-872	47	3	of	of	ADP
mkg-872	47	4	interleukine	interleukine	ADJ
mkg-872	47	5	/	/	SYM
mkg-872	47	6	il-1α	il-1α	PROPN
mkg-872	47	7	,	,	PUNCT
mkg-872	47	8	il-6	il-6	NOUN
mkg-872	47	9	and	and	CCONJ
mkg-872	47	10	il-8	il-8	PRON
mkg-872	47	11	were	be	AUX
mkg-872	47	12	found	find	VERB
mkg-872	47	13	in	in	ADP
mkg-872	47	14	whole	whole	ADJ
mkg-872	47	15	saliva	saliva	NOUN
mkg-872	47	16	at	at	ADP
mkg-872	47	17	signifi	signifi	NOUN
mkg-872	47	18	cantly	cantly	ADV
mkg-872	47	19	higher	high	ADJ
mkg-872	47	20	than	than	ADP
mkg-872	47	21	in	in	ADP
mkg-872	47	22	major	major	ADJ
mkg-872	47	23	salivary	salivary	ADJ
mkg-872	47	24	gland	gland	NOUN
mkg-872	47	25	secretions	secretion	NOUN
mkg-872	47	26	.	.	PUNCT
mkg-872	48	1	in	in	ADP
mkg-872	48	2	another	another	DET
mkg-872	48	3	study	study	NOUN
mkg-872	48	4	,	,	PUNCT
mkg-872	48	5	transforming	transform	VERB
mkg-872	48	6	growth	growth	NOUN
mkg-872	48	7	factor	factor	NOUN
mkg-872	48	8	(	(	PUNCT
mkg-872	48	9	tgf)-β	tgf)-β	PROPN
mkg-872	48	10	,	,	PUNCT
mkg-872	48	11	interleukin	interleukin	NOUN
mkg-872	48	12	(	(	PUNCT
mkg-872	48	13	il)-1α	il)-1α	NOUN
mkg-872	48	14	and	and	CCONJ
mkg-872	48	15	tumour	tumour	NOUN
mkg-872	48	16	necrosis	necrosis	NOUN
mkg-872	48	17	factor	factor	NOUN
mkg-872	48	18	(	(	PUNCT
mkg-872	48	19	tnf)-α	tnf)-α	NOUN
mkg-872	48	20	were	be	AUX
mkg-872	48	21	statistically	statistically	ADV
mkg-872	48	22	signifi	signifi	VERB
mkg-872	48	23	cantly	cantly	ADV
mkg-872	48	24	higher	high	ADJ
mkg-872	48	25	in	in	ADP
mkg-872	48	26	whole	whole	ADJ
mkg-872	48	27	saliva	saliva	NOUN
mkg-872	48	28	compared	compare	VERB
mkg-872	48	29	to	to	ADP
mkg-872	48	30	parotid	parotid	ADJ
mkg-872	48	31	saliva	saliva	NOUN
mkg-872	48	32	.	.	PUNCT
mkg-872	49	1	although	although	SCONJ
mkg-872	49	2	not	not	PART
mkg-872	49	3	statistically	statistically	ADV
mkg-872	49	4	signifi	signifi	VERB
mkg-872	49	5	ca	can	AUX
mkg-872	49	6	nt	not	PART
mkg-872	49	7	,	,	PUNCT
mkg-872	49	8	il-8	il-8	NOUN
mkg-872	49	9	and	and	CCONJ
mkg-872	49	10	il-6	il-6	NOUN
mkg-872	49	11	also	also	ADV
mkg-872	49	12	displayed	display	VERB
mkg-872	49	13	a	a	DET
mkg-872	49	14	trend	trend	NOUN
mkg-872	49	15	towards	towards	ADP
mkg-872	49	16	higher	high	ADJ
mkg-872	49	17	levels	level	NOUN
mkg-872	49	18	in	in	ADP
mkg-872	49	19	whole	whole	ADJ
mkg-872	49	20	saliva	saliva	NOUN
mkg-872	49	21	.	.	PUNCT
mkg-872	50	1	the	the	DET
mkg-872	50	2	other	other	ADJ
mkg-872	50	3	study	study	NOUN
mkg-872	50	4	examined	examine	VERB
mkg-872	50	5	the	the	DET
mkg-872	50	6	relationship	relationship	NOUN
mkg-872	50	7	between	between	ADP
mkg-872	50	8	clinical	clinical	ADJ
mkg-872	50	9	parameters	parameter	NOUN
mkg-872	50	10	of	of	ADP
mkg-872	50	11	periodontal	periodontal	ADJ
mkg-872	50	12	disease	disease	NOUN
mkg-872	50	13	and	and	CCONJ
mkg-872	50	14	the	the	DET
mkg-872	50	15	levels	level	NOUN
mkg-872	50	16	of	of	ADP
mkg-872	50	17	il-1β	il-1β	PROPN
mkg-872	50	18	,	,	PUNCT
mkg-872	50	19	matrix	matrix	NOUN
mkg-872	50	20	metalloproteinase	metalloproteinase	NOUN
mkg-872	50	21	(	(	PUNCT
mkg-872	50	22	mmp)-8	mmp)-8	ADJ
mkg-872	50	23	,	,	PUNCT
mkg-872	50	24	and	and	CCONJ
mkg-872	50	25	osteoprotegerin	osteoprotegerin	NOUN
mkg-872	50	26	(	(	PUNCT
mkg-872	50	27	opg	opg	PROPN
mkg-872	50	28	)	)	PUNCT
mkg-872	50	29	in	in	ADP
mkg-872	50	30	whole	whole	ADJ
mkg-872	50	31	saliva	saliva	NOUN
mkg-872	50	32	.	.	PUNCT
mkg-872	51	1	they	they	PRON
mkg-872	51	2	reported	report	VERB
mkg-872	51	3	that	that	SCONJ
mkg-872	51	4	the	the	DET
mkg-872	51	5	mean	mean	ADJ
mkg-872	51	6	levels	level	NOUN
mkg-872	51	7	of	of	ADP
mkg-872	51	8	il-1β	il-1β	PROPN
mkg-872	51	9	and	and	CCONJ
mkg-872	51	10	mmp-8	mmp-8	ADV
mkg-872	51	11	in	in	ADP
mkg-872	51	12	saliva	saliva	NOUN
mkg-872	51	13	were	be	AUX
mkg-872	51	14	signifi	signifi	NOUN
mkg-872	51	15	cantly	cantly	ADV
mkg-872	51	16	higher	high	ADJ
mkg-872	51	17	in	in	ADP
mkg-872	51	18	periodontitis	periodontitis	NOUN
mkg-872	51	19	subjects	subject	NOUN
mkg-872	51	20	than	than	ADP
mkg-872	51	21	in	in	ADP
mkg-872	51	22	periodontally	periodontally	ADV
mkg-872	51	23	healthy	healthy	ADJ
mkg-872	51	24	controls	control	NOUN
mkg-872	51	25	.	.	PUNCT
mkg-872	52	1	combined	combined	ADJ
mkg-872	52	2	elevated	elevated	ADJ
mkg-872	52	3	salivary	salivary	ADJ
mkg-872	52	4	levels	level	NOUN
mkg-872	52	5	of	of	ADP
mkg-872	52	6	mmp-8	mmp-8	NUM
mkg-872	52	7	and	and	CCONJ
mkg-872	52	8	il-1β	il-1β	PROPN
mkg-872	52	9	increased	increase	VERB
mkg-872	52	10	the	the	DET
mkg-872	52	11	risk	risk	NOUN
mkg-872	52	12	of	of	ADP
mkg-872	52	13	experiencing	experience	VERB
mkg-872	52	14	periodontal	periodontal	ADJ
mkg-872	52	15	disease	disease	NOUN
mkg-872	52	16	45	45	NUM
mkg-872	52	17	-	-	NOUN
mkg-872	52	18	fold	fold	ADJ
mkg-872	52	19	.	.	PUNCT
mkg-872	53	1	among	among	ADP
mkg-872	53	2	the	the	DET
mkg-872	53	3	salivary	salivary	ADJ
mkg-872	53	4	cytokines	cytokine	NOUN
mkg-872	53	5	(	(	PUNCT
mkg-872	53	6	il-1β	il-1β	PROPN
mkg-872	53	7	,	,	PUNCT
mkg-872	53	8	il-6	il-6	NUM
mkg-872	53	9	,	,	PUNCT
mkg-872	53	10	and	and	CCONJ
mkg-872	53	11	tnf	tnf	PROPN
mkg-872	53	12	-	-	PUNCT
mkg-872	53	13	α	α	PROPN
mkg-872	53	14	,	,	PUNCT
mkg-872	53	15	)	)	PUNCT
mkg-872	53	16	,	,	PUNCT
mkg-872	53	17	il-1β	il-1β	PROPN
mkg-872	53	18	was	be	AUX
mkg-872	53	19	the	the	DET
mkg-872	53	20	only	only	ADJ
mkg-872	53	21	biomarker	biomarker	NOUN
mkg-872	53	22	associated	associate	VERB
mkg-872	53	23	with	with	ADP
mkg-872	53	24	periodontitis	periodontitis	NOUN
mkg-872	53	25	.	.	PUNCT
mkg-872	54	1	they	they	PRON
mkg-872	54	2	suggest	suggest	VERB
mkg-872	54	3	that	that	SCONJ
mkg-872	54	4	salivary	salivary	VERB
mkg-872	54	5	il-1β	il-1β	PROPN
mkg-872	54	6	in	in	ADP
mkg-872	54	7	saliva	saliva	NOUN
mkg-872	54	8	more	more	ADV
mkg-872	54	9	thoroughly	thoroughly	ADV
mkg-872	54	10	as	as	SCONJ
mkg-872	54	11	markers	marker	NOUN
mkg-872	54	12	of	of	ADP
mkg-872	54	13	periodontitis.3,12	periodontitis.3,12	PROPN
mkg-872	54	14	-	-	SYM
mkg-872	54	15	17	17	NUM
mkg-872	54	16	opg	opg	NOUN
mkg-872	54	17	is	be	AUX
mkg-872	54	18	glycoprotein	glycoprotein	NOUN
mkg-872	54	19	that	that	PRON
mkg-872	54	20	inhibits	inhibit	VERB
mkg-872	54	21	osteoclast	osteoclast	ADJ
mkg-872	54	22	differentiation	differentiation	NOUN
mkg-872	54	23	an	an	DET
mkg-872	54	24	activity	activity	NOUN
mkg-872	54	25	competitively	competitively	ADV
mkg-872	54	26	by	by	ADP
mkg-872	54	27	preventing	prevent	VERB
mkg-872	54	28	osteoclast	osteoclast	ADJ
mkg-872	54	29	differentiatin	differentiatin	ADJ
mkg-872	54	30	factor	factor	NOUN
mkg-872	54	31	receptor	receptor	NOUN
mkg-872	54	32	activator	activator	NOUN
mkg-872	54	33	of	of	ADP
mkg-872	54	34	nuclear	nuclear	ADJ
mkg-872	54	35	factor	factor	NOUN
mkg-872	54	36	kappa	kappa	ADJ
mkg-872	54	37	-	-	ADJ
mkg-872	54	38	beta	beta	ADJ
mkg-872	54	39	ligand	ligand	NOUN
mkg-872	54	40	(	(	PUNCT
mkg-872	54	41	rankl	rankl	PROPN
mkg-872	54	42	)	)	PUNCT
mkg-872	54	43	from	from	ADP
mkg-872	54	44	binding	bind	VERB
mkg-872	54	45	to	to	ADP
mkg-872	54	46	osteoclast	osteoclast	ADJ
mkg-872	54	47	precursor	precursor	NOUN
mkg-872	54	48	and	and	CCONJ
mkg-872	54	49	promoting	promote	VERB
mkg-872	54	50	the	the	DET
mkg-872	54	51	formation	formation	NOUN
mkg-872	54	52	of	of	ADP
mkg-872	54	53	bone	bone	NOUN
mkg-872	54	54	-	-	PUNCT
mkg-872	54	55	resorbing	resorb	VERB
mkg-872	54	56	osteoclast	osteoclast	NOUN
mkg-872	54	57	.	.	PUNCT
mkg-872	55	1	opg	opg	PROPN
mkg-872	55	2	used	use	VERB
mkg-872	55	3	as	as	ADP
mkg-872	55	4	a	a	DET
mkg-872	55	5	marker	marker	NOUN
mkg-872	55	6	of	of	ADP
mkg-872	55	7	bone	bone	NOUN
mkg-872	55	8	turnover.4,5	turnover.4,5	NUM
mkg-872	55	9	oncostatin	oncostatin	NOUN
mkg-872	55	10	m	m	PROPN
mkg-872	55	11	(	(	PUNCT
mkg-872	55	12	osm	osm	PROPN
mkg-872	55	13	)	)	PUNCT
mkg-872	55	14	,	,	PUNCT
mkg-872	55	15	a	a	DET
mkg-872	55	16	member	member	NOUN
mkg-872	55	17	of	of	ADP
mkg-872	55	18	the	the	DET
mkg-872	55	19	il-6	il-6	NOUN
mkg-872	55	20	family	family	NOUN
mkg-872	55	21	of	of	ADP
mkg-872	55	22	cytokines	cytokine	NOUN
mkg-872	55	23	,	,	PUNCT
mkg-872	55	24	is	be	AUX
mkg-872	55	25	multifunctional	multifunctional	ADJ
mkg-872	55	26	unique	unique	ADJ
mkg-872	55	27	cytokine	cytokine	NOUN
mkg-872	55	28	that	that	PRON
mkg-872	55	29	plays	play	VERB
mkg-872	55	30	an	an	DET
mkg-872	55	31	important	important	ADJ
mkg-872	55	32	role	role	NOUN
mkg-872	55	33	in	in	ADP
mkg-872	55	34	various	various	ADJ
mkg-872	55	35	biological	biological	ADJ
mkg-872	55	36	systems	system	NOUN
mkg-872	55	37	such	such	ADJ
mkg-872	55	38	as	as	ADP
mkg-872	55	39	infl	infl	PROPN
mkg-872	55	40	ammatory	ammatory	NOUN
mkg-872	55	41	response	response	NOUN
mkg-872	55	42	,	,	PUNCT
mkg-872	55	43	haematopoiesis	haematopoiesis	NOUN
mkg-872	55	44	,	,	PUNCT
mkg-872	55	45	tissue	tissue	NOUN
mkg-872	55	46	remodelling	remodelling	NOUN
mkg-872	55	47	and	and	CCONJ
mkg-872	55	48	development.13	development.13	NOUN
mkg-872	55	49	in	in	ADP
mkg-872	55	50	periodontitis	periodontitis	NOUN
mkg-872	55	51	,	,	PUNCT
mkg-872	55	52	osm	osm	PROPN
mkg-872	55	53	alone	alone	ADV
mkg-872	55	54	may	may	AUX
mkg-872	55	55	stimulate	stimulate	VERB
mkg-872	55	56	the	the	DET
mkg-872	55	57	production	production	NOUN
mkg-872	55	58	of	of	ADP
mkg-872	55	59	il-6	il-6	NUM
mkg-872	55	60	,	,	PUNCT
mkg-872	55	61	or	or	CCONJ
mkg-872	55	62	it	it	PRON
mkg-872	55	63	may	may	AUX
mkg-872	55	64	act	act	VERB
mkg-872	55	65	synergistically	synergistically	ADV
mkg-872	55	66	with	with	ADP
mkg-872	55	67	il-6	il-6	PRON
mkg-872	55	68	or	or	CCONJ
mkg-872	55	69	tnf	tnf	PROPN
mkg-872	55	70	-	-	PUNCT
mkg-872	55	71	α	α	NOUN
mkg-872	55	72	to	to	PART
mkg-872	55	73	upregulate	upregulate	VERB
mkg-872	55	74	the	the	DET
mkg-872	55	75	production	production	NOUN
mkg-872	55	76	of	of	ADP
mkg-872	55	77	mmps	mmp	NOUN
mkg-872	55	78	or	or	CCONJ
mkg-872	55	79	augment	augment	VERB
mkg-872	55	80	il-6	il-6	NOUN
mkg-872	55	81	production	production	NOUN
mkg-872	55	82	.	.	PUNCT
mkg-872	56	1	il-6	il-6	NOUN
mkg-872	56	2	may	may	AUX
mkg-872	56	3	act	act	VERB
mkg-872	56	4	on	on	ADP
mkg-872	56	5	both	both	CCONJ
mkg-872	56	6	the	the	DET
mkg-872	56	7	osteoblasts	osteoblast	NOUN
mkg-872	56	8	and	and	CCONJ
mkg-872	56	9	osteoclasts	osteoclast	NOUN
mkg-872	56	10	through	through	ADP
mkg-872	56	11	autocrine	autocrine	NOUN
mkg-872	56	12	and	and	CCONJ
mkg-872	56	13	paracrine	paracrine	NOUN
mkg-872	56	14	rankl	rankl	VERB
mkg-872	56	15	regulation	regulation	NOUN
mkg-872	56	16	causing	cause	VERB
mkg-872	56	17	bone	bone	NOUN
mkg-872	56	18	resorption	resorption	NOUN
mkg-872	56	19	.	.	PUNCT
mkg-872	57	1	osm	osm	NOUN
mkg-872	57	2	as	as	ADP
mkg-872	57	3	an	an	DET
mkg-872	57	4	infl	infl	PROPN
mkg-872	57	5	ammatory	ammatory	NOUN
mkg-872	57	6	and	and	CCONJ
mkg-872	57	7	bone	bone	NOUN
mkg-872	57	8	resorptive	resorptive	ADJ
mkg-872	57	9	biomarker	biomarker	NOUN
mkg-872	57	10	of	of	ADP
mkg-872	57	11	periodontal	periodontal	ADJ
mkg-872	57	12	disease.15	disease.15	NOUN
mkg-872	57	13	salivary	salivary	ADJ
mkg-872	57	14	indicators	indicator	NOUN
mkg-872	57	15	such	such	ADJ
mkg-872	57	16	as	as	ADP
mkg-872	57	17	intracellular	intracellular	ADJ
mkg-872	57	18	enzymes	enzyme	NOUN
mkg-872	57	19	are	be	AUX
mkg-872	57	20	increasingly	increasingly	ADV
mkg-872	57	21	released	release	VERB
mkg-872	57	22	from	from	ADP
mkg-872	57	23	the	the	DET
mkg-872	57	24	damaged	damage	VERB
mkg-872	57	25	cells	cell	NOUN
mkg-872	57	26	of	of	ADP
mkg-872	57	27	periodontal	periodontal	ADJ
mkg-872	57	28	tissues	tissue	NOUN
mkg-872	57	29	into	into	ADP
mkg-872	57	30	the	the	DET
mkg-872	57	31	gingival	gingival	NOUN
mkg-872	57	32	crevicular	crevicular	NOUN
mkg-872	57	33	fl	fl	ADP
mkg-872	57	34	uid	uid	PROPN
mkg-872	57	35	(	(	PUNCT
mkg-872	57	36	gcf	gcf	PROPN
mkg-872	57	37	)	)	PUNCT
mkg-872	57	38	and	and	CCONJ
mkg-872	57	39	saliva.2	saliva.2	VERB
mkg-872	57	40	the	the	DET
mkg-872	57	41	activities	activity	NOUN
mkg-872	57	42	several	several	ADJ
mkg-872	57	43	enzymes	enzyme	NOUN
mkg-872	57	44	of	of	ADP
mkg-872	57	45	periodontal	periodontal	ADJ
mkg-872	57	46	disease	disease	NOUN
mkg-872	57	47	such	such	ADJ
mkg-872	57	48	as	as	ADP
mkg-872	57	49	creatine	creatine	PROPN
mkg-872	57	50	kinase	kinase	PROPN
mkg-872	57	51	(	(	PUNCT
mkg-872	57	52	ck	ck	PROPN
mkg-872	57	53	)	)	PUNCT
mkg-872	57	54	,	,	PUNCT
mkg-872	57	55	lactate	lactate	NOUN
mkg-872	57	56	dehydrogenase	dehydrogenase	NOUN
mkg-872	57	57	(	(	PUNCT
mkg-872	57	58	ldh	ldh	NOUN
mkg-872	57	59	)	)	PUNCT
mkg-872	57	60	,	,	PUNCT
mkg-872	57	61	aspartate	aspartate	NOUN
mkg-872	57	62	aminotransferase	aminotransferase	NOUN
mkg-872	57	63	(	(	PUNCT
mkg-872	57	64	ast	ast	PROPN
mkg-872	57	65	)	)	PUNCT
mkg-872	57	66	,	,	PUNCT
mkg-872	57	67	alanine	alanine	NOUN
mkg-872	57	68	aminotransferase	aminotransferase	PROPN
mkg-872	57	69	(	(	PUNCT
mkg-872	57	70	alt	alt	PROPN
mkg-872	57	71	)	)	PUNCT
mkg-872	57	72	,	,	PUNCT
mkg-872	57	73	gamma	gamma	PROPN
mkg-872	57	74	glutamil	glutamil	PROPN
mkg-872	57	75	transferase	transferase	NOUN
mkg-872	57	76	(	(	PUNCT
mkg-872	57	77	ggt	ggt	NOUN
mkg-872	57	78	)	)	PUNCT
mkg-872	57	79	,	,	PUNCT
mkg-872	57	80	alkaline	alkaline	NOUN
mkg-872	57	81	phosphatase	phosphatase	NOUN
mkg-872	57	82	(	(	PUNCT
mkg-872	57	83	alp	alp	PROPN
mkg-872	57	84	)	)	PUNCT
mkg-872	57	85	and	and	CCONJ
mkg-872	57	86	acid	acid	ADJ
mkg-872	57	87	phosphatase	phosphatase	NOUN
mkg-872	57	88	(	(	PUNCT
mkg-872	57	89	acp	acp	PROPN
mkg-872	57	90	)	)	PUNCT
mkg-872	57	91	enzymes	enzyme	NOUN
mkg-872	57	92	were	be	AUX
mkg-872	57	93	signifi	signifi	NOUN
mkg-872	57	94	cantly	cantly	ADV
mkg-872	57	95	increased	increase	VERB
mkg-872	57	96	in	in	ADP
mkg-872	57	97	the	the	DET
mkg-872	57	98	saliva	saliva	NOUN
mkg-872	57	99	of	of	ADP
mkg-872	57	100	patients	patient	NOUN
mkg-872	57	101	with	with	ADP
mkg-872	57	102	periodontal	periodontal	ADJ
mkg-872	57	103	disease	disease	NOUN
mkg-872	57	104	when	when	SCONJ
mkg-872	57	105	compared	compare	VERB
mkg-872	57	106	to	to	ADP
mkg-872	57	107	healthy	healthy	ADJ
mkg-872	57	108	subjects	subject	NOUN
mkg-872	57	109	.	.	PUNCT
mkg-872	58	1	79hamzah	79hamzah	NOUN
mkg-872	58	2	:	:	PUNCT
mkg-872	58	3	saliva	saliva	NOUN
mkg-872	58	4	as	as	ADP
mkg-872	58	5	a	a	DET
mkg-872	58	6	future	future	ADJ
mkg-872	58	7	potential	potential	ADJ
mkg-872	58	8	predictor	predictor	NOUN
mkg-872	58	9	meanwhile	meanwhile	ADV
mkg-872	58	10	,	,	PUNCT
mkg-872	58	11	other	other	ADJ
mkg-872	58	12	investigators	investigator	NOUN
mkg-872	58	13	reported	report	VERB
mkg-872	58	14	that	that	SCONJ
mkg-872	58	15	enzymes	enzyme	NOUN
mkg-872	58	16	elastase	elastase	NOUN
mkg-872	58	17	,	,	PUNCT
mkg-872	58	18	ldh	ldh	PROPN
mkg-872	58	19	was	be	AUX
mkg-872	58	20	the	the	DET
mkg-872	58	21	only	only	ADJ
mkg-872	58	22	biomarker	biomarker	NOUN
mkg-872	58	23	associated	associate	VERB
mkg-872	58	24	with	with	ADP
mkg-872	58	25	periodontitis	periodontitis	NOUN
mkg-872	58	26	.	.	PUNCT
mkg-872	59	1	ldh	ldh	PROPN
mkg-872	59	2	activity	activity	NOUN
mkg-872	59	3	increased	increase	VERB
mkg-872	59	4	proportionally	proportionally	ADV
mkg-872	59	5	with	with	ADP
mkg-872	59	6	the	the	DET
mkg-872	59	7	advance	advance	NOUN
mkg-872	59	8	of	of	ADP
mkg-872	59	9	periodontitis.12,18–21	periodontitis.12,18–21	PROPN
mkg-872	59	10	the	the	DET
mkg-872	59	11	other	other	ADJ
mkg-872	59	12	marker	marker	NOUN
mkg-872	59	13	of	of	ADP
mkg-872	59	14	the	the	DET
mkg-872	59	15	acute	acute	PROPN
mkg-872	59	16	infl	infl	PROPN
mkg-872	59	17	ammatory	ammatory	NOUN
mkg-872	59	18	response	response	NOUN
mkg-872	59	19	is	be	AUX
mkg-872	59	20	immunoglobulin	immunoglobulin	NOUN
mkg-872	59	21	.	.	PUNCT
mkg-872	60	1	levels	level	NOUN
mkg-872	60	2	of	of	ADP
mkg-872	60	3	immunoglobulin	immunoglobulin	NOUN
mkg-872	60	4	g	g	PROPN
mkg-872	60	5	(	(	PUNCT
mkg-872	60	6	igg	igg	PROPN
mkg-872	60	7	)	)	PUNCT
mkg-872	60	8	have	have	AUX
mkg-872	60	9	been	be	AUX
mkg-872	60	10	found	find	VERB
mkg-872	60	11	not	not	PART
mkg-872	60	12	to	to	PART
mkg-872	60	13	have	have	VERB
mkg-872	60	14	a	a	DET
mkg-872	60	15	consistent	consistent	ADJ
mkg-872	60	16	association	association	NOUN
mkg-872	60	17	with	with	ADP
mkg-872	60	18	periodontal	periodontal	ADJ
mkg-872	60	19	disease	disease	NOUN
mkg-872	60	20	,	,	PUNCT
mkg-872	60	21	although	although	SCONJ
mkg-872	60	22	subtypes	subtype	NOUN
mkg-872	60	23	of	of	ADP
mkg-872	60	24	igg	igg	PROPN
mkg-872	60	25	may	may	AUX
mkg-872	60	26	be	be	AUX
mkg-872	60	27	found	find	VERB
mkg-872	60	28	in	in	ADP
mkg-872	60	29	subjects	subject	NOUN
mkg-872	60	30	at	at	ADP
mkg-872	60	31	higher	high	ADJ
mkg-872	60	32	risk	risk	NOUN
mkg-872	60	33	for	for	ADP
mkg-872	60	34	periodontal	periodontal	ADJ
mkg-872	60	35	disease	disease	NOUN
mkg-872	60	36	progression	progression	NOUN
mkg-872	60	37	.	.	PUNCT
mkg-872	61	1	levels	level	NOUN
mkg-872	61	2	of	of	ADP
mkg-872	61	3	immunoglobulin	immunoglobulin	NOUN
mkg-872	61	4	have	have	AUX
mkg-872	61	5	been	be	AUX
mkg-872	61	6	found	find	VERB
mkg-872	61	7	not	not	PART
mkg-872	61	8	to	to	PART
mkg-872	61	9	have	have	VERB
mkg-872	61	10	a	a	DET
mkg-872	61	11	consistent	consistent	ADJ
mkg-872	61	12	association	association	NOUN
mkg-872	61	13	with	with	ADP
mkg-872	61	14	risk	risk	NOUN
mkg-872	61	15	for	for	ADP
mkg-872	61	16	periodontal	periodontal	ADJ
mkg-872	61	17	disease	disease	NOUN
mkg-872	61	18	progression.4,5	progression.4,5	NOUN
mkg-872	61	19	there	there	PRON
mkg-872	61	20	are	be	VERB
mkg-872	61	21	relationship	relationship	NOUN
mkg-872	61	22	of	of	ADP
mkg-872	61	23	periodontal	periodontal	ADJ
mkg-872	61	24	parameters	parameter	NOUN
mkg-872	61	25	to	to	ADP
mkg-872	61	26	the	the	DET
mkg-872	61	27	presence	presence	NOUN
mkg-872	61	28	of	of	ADP
mkg-872	61	29	these	these	DET
mkg-872	61	30	periodontopathic	periodontopathic	ADJ
mkg-872	61	31	bacteria	bacteria	NOUN
mkg-872	61	32	.	.	PUNCT
mkg-872	62	1	most	most	ADJ
mkg-872	62	2	of	of	ADP
mkg-872	62	3	bacteria	bacteria	NOUN
mkg-872	62	4	can	can	AUX
mkg-872	62	5	produce	produce	VERB
mkg-872	62	6	tissue	tissue	NOUN
mkg-872	62	7	destruction	destruction	NOUN
mkg-872	62	8	by	by	ADP
mkg-872	62	9	two	two	NUM
mkg-872	62	10	ways	way	NOUN
mkg-872	62	11	:	:	PUNCT
mkg-872	62	12	directly	directly	ADV
mkg-872	62	13	,	,	PUNCT
mkg-872	62	14	through	through	ADP
mkg-872	62	15	invasion	invasion	NOUN
mkg-872	62	16	of	of	ADP
mkg-872	62	17	the	the	DET
mkg-872	62	18	tissue	tissue	NOUN
mkg-872	62	19	and	and	CCONJ
mkg-872	62	20	production	production	NOUN
mkg-872	62	21	of	of	ADP
mkg-872	62	22	harmful	harmful	ADJ
mkg-872	62	23	substances	substance	NOUN
mkg-872	62	24	that	that	PRON
mkg-872	62	25	induce	induce	VERB
mkg-872	62	26	cell	cell	NOUN
mkg-872	62	27	death	death	NOUN
mkg-872	62	28	and	and	CCONJ
mkg-872	62	29	tissue	tissue	NOUN
mkg-872	62	30	necrosis	necrosis	NOUN
mkg-872	62	31	;	;	PUNCT
mkg-872	62	32	and	and	CCONJ
mkg-872	62	33	indirectly	indirectly	ADV
mkg-872	62	34	,	,	PUNCT
mkg-872	62	35	through	through	ADP
mkg-872	62	36	activation	activation	NOUN
mkg-872	62	37	of	of	ADP
mkg-872	62	38	inflammatory	inflammatory	ADJ
mkg-872	62	39	cells	cell	NOUN
mkg-872	62	40	that	that	PRON
mkg-872	62	41	can	can	AUX
mkg-872	62	42	produce	produce	VERB
mkg-872	62	43	and	and	CCONJ
mkg-872	62	44	release	release	VERB
mkg-872	62	45	mediators	mediator	NOUN
mkg-872	62	46	that	that	PRON
mkg-872	62	47	act	act	VERB
mkg-872	62	48	on	on	ADP
mkg-872	62	49	effector	effector	NOUN
mkg-872	62	50	,	,	PUNCT
mkg-872	62	51	with	with	ADP
mkg-872	62	52	potent	potent	ADJ
mkg-872	62	53	inflammatory	inflammatory	ADJ
mkg-872	62	54	and	and	CCONJ
mkg-872	62	55	catabolic	catabolic	ADJ
mkg-872	62	56	activity	activity	NOUN
mkg-872	62	57	.	.	PUNCT
mkg-872	63	1	the	the	DET
mkg-872	63	2	pathogenesis	pathogenesis	NOUN
mkg-872	63	3	of	of	ADP
mkg-872	63	4	periodontal	periodontal	ADJ
mkg-872	63	5	destruction	destruction	NOUN
mkg-872	63	6	involves	involve	VERB
mkg-872	63	7	the	the	DET
mkg-872	63	8	sequential	sequential	ADJ
mkg-872	63	9	activation	activation	NOUN
mkg-872	63	10	of	of	ADP
mkg-872	63	11	different	different	ADJ
mkg-872	63	12	components	component	NOUN
mkg-872	63	13	of	of	ADP
mkg-872	63	14	the	the	DET
mkg-872	63	15	host	host	NOUN
mkg-872	63	16	immune	immune	ADJ
mkg-872	63	17	and	and	CCONJ
mkg-872	63	18	inflammatory	inflammatory	ADJ
mkg-872	63	19	response.22	response.22	NOUN
mkg-872	63	20	in	in	ADP
mkg-872	63	21	chronic	chronic	ADJ
mkg-872	63	22	gingivitis	gingivitis	NOUN
mkg-872	63	23	,	,	PUNCT
mkg-872	63	24	gram	gram	NOUN
mkg-872	63	25	-	-	PUNCT
mkg-872	63	26	negative	negative	ADJ
mkg-872	63	27	bacteria	bacteria	NOUN
mkg-872	63	28	constitute	constitute	VERB
mkg-872	63	29	±	±	NUM
mkg-872	63	30	45	45	NUM
mkg-872	63	31	%	%	NOUN
mkg-872	63	32	and	and	CCONJ
mkg-872	63	33	anaerobic	anaerobic	ADJ
mkg-872	63	34	organisms	organism	NOUN
mkg-872	63	35	±	±	NUM
mkg-872	63	36	45	45	NUM
mkg-872	63	37	%	%	NOUN
mkg-872	63	38	of	of	ADP
mkg-872	63	39	the	the	DET
mkg-872	63	40	total	total	ADJ
mkg-872	63	41	recoverable	recoverable	ADJ
mkg-872	63	42	subgingival	subgingival	ADJ
mkg-872	63	43	flora	flora	NOUN
mkg-872	63	44	.	.	PUNCT
mkg-872	64	1	predominant	predominant	ADJ
mkg-872	64	2	isolates	isolate	NOUN
mkg-872	64	3	include	include	VERB
mkg-872	64	4	various	various	ADJ
mkg-872	64	5	species	specie	NOUN
mkg-872	64	6	of	of	ADP
mkg-872	64	7	actinomyces	actinomyce	NOUN
mkg-872	64	8	,	,	PUNCT
mkg-872	64	9	streptococcus	streptococcus	NOUN
mkg-872	64	10	,	,	PUNCT
mkg-872	64	11	fusobacterium	fusobacterium	NOUN
mkg-872	64	12	,	,	PUNCT
mkg-872	64	13	and	and	CCONJ
mkg-872	64	14	bacteroides	bacteroide	NOUN
mkg-872	64	15	,	,	PUNCT
mkg-872	64	16	as	as	ADV
mkg-872	64	17	well	well	ADV
mkg-872	64	18	as	as	ADP
mkg-872	64	19	eikenella	eikenella	ADJ
mkg-872	64	20	corrodens	corroden	NOUN
mkg-872	64	21	and	and	CCONJ
mkg-872	64	22	capnocytophaga	capnocytophaga	PROPN
mkg-872	64	23	gingivalis	gingivalis	PROPN
mkg-872	64	24	.	.	PUNCT
mkg-872	65	1	acute	acute	ADJ
mkg-872	65	2	necrotizing	necrotize	VERB
mkg-872	65	3	ulcerative	ulcerative	ADJ
mkg-872	65	4	gingivitis	gingivitis	NOUN
mkg-872	65	5	(	(	PUNCT
mkg-872	65	6	anug	anug	PROPN
mkg-872	65	7	)	)	PUNCT
mkg-872	65	8	has	have	AUX
mkg-872	65	9	been	be	AUX
mkg-872	65	10	associated	associate	VERB
mkg-872	65	11	with	with	ADP
mkg-872	65	12	high	high	ADJ
mkg-872	65	13	proportions	proportion	NOUN
mkg-872	65	14	of	of	ADP
mkg-872	65	15	bacteroides	bacteroide	NOUN
mkg-872	65	16	intermedius	intermedius	NOUN
mkg-872	65	17	and	and	CCONJ
mkg-872	65	18	treponema	treponema	VERB
mkg-872	65	19	.	.	PUNCT
mkg-872	66	1	advanced	advanced	ADJ
mkg-872	66	2	adult	adult	NOUN
mkg-872	66	3	periodontitis	periodontitis	NOUN
mkg-872	66	4	lesions	lesion	NOUN
mkg-872	66	5	are	be	AUX
mkg-872	66	6	characterized	characterize	VERB
mkg-872	66	7	by	by	ADP
mkg-872	66	8	approximately	approximately	ADV
mkg-872	66	9	75	75	NUM
mkg-872	66	10	%	%	NOUN
mkg-872	66	11	gram	gram	NOUN
mkg-872	66	12	-	-	PUNCT
mkg-872	66	13	negative	negative	ADJ
mkg-872	66	14	and	and	CCONJ
mkg-872	66	15	90	90	NUM
mkg-872	66	16	%	%	NOUN
mkg-872	66	17	anaerobic	anaerobic	NOUN
mkg-872	66	18	organisms	organism	NOUN
mkg-872	66	19	.	.	PUNCT
mkg-872	67	1	common	common	ADJ
mkg-872	67	2	isolates	isolate	NOUN
mkg-872	67	3	include	include	VERB
mkg-872	67	4	bacteroides	bacteroide	NOUN
mkg-872	67	5	gingivalis	gingivalis	PROPN
mkg-872	67	6	,	,	PUNCT
mkg-872	67	7	b.	b.	PROPN
mkg-872	67	8	intermedius	intermedius	PROPN
mkg-872	67	9	,	,	PUNCT
mkg-872	67	10	actinobacillus	actinobacillus	ADJ
mkg-872	67	11	actinomycetemcomitans	actinomycetemcomitan	NOUN
mkg-872	67	12	,	,	PUNCT
mkg-872	67	13	prevotella	prevotella	NOUN
mkg-872	67	14	intermedia	intermedia	PROPN
mkg-872	67	15	(	(	PUNCT
mkg-872	67	16	pi	pi	NOUN
mkg-872	67	17	)	)	PUNCT
mkg-872	67	18	,	,	PUNCT
mkg-872	67	19	and	and	CCONJ
mkg-872	67	20	tannerella	tannerella	NOUN
mkg-872	67	21	forsythensis	forsythensis	NOUN
mkg-872	67	22	(	(	PUNCT
mkg-872	67	23	tf	tf	X
mkg-872	67	24	)	)	PUNCT
mkg-872	67	25	and	and	CCONJ
mkg-872	67	26	various	various	ADJ
mkg-872	67	27	species	specie	NOUN
mkg-872	67	28	of	of	ADP
mkg-872	67	29	fusobacterium	fusobacterium	NOUN
mkg-872	67	30	,	,	PUNCT
mkg-872	67	31	wolinella	wolinella	PROPN
mkg-872	67	32	,	,	PUNCT
mkg-872	67	33	capnocytophaga	capnocytophaga	NOUN
mkg-872	67	34	species	specie	NOUN
mkg-872	67	35	,	,	PUNCT
mkg-872	67	36	campylobacter	campylobacter	NOUN
mkg-872	67	37	rectus	rectus	NOUN
mkg-872	67	38	,	,	PUNCT
mkg-872	67	39	and	and	CCONJ
mkg-872	67	40	non	non	ADJ
mkg-872	67	41	-	-	ADJ
mkg-872	67	42	pigmenting	pigmenting	ADJ
mkg-872	67	43	bacteroides	bacteroide	NOUN
mkg-872	67	44	.	.	PUNCT
mkg-872	68	1	in	in	ADP
mkg-872	68	2	recent	recent	ADJ
mkg-872	68	3	studies	study	NOUN
mkg-872	68	4	of	of	ADP
mkg-872	68	5	the	the	DET
mkg-872	68	6	analysis	analysis	NOUN
mkg-872	68	7	microbiota	microbiota	NOUN
mkg-872	68	8	associated	associate	VERB
mkg-872	68	9	with	with	ADP
mkg-872	68	10	identify	identify	VERB
mkg-872	68	11	specific	specific	ADJ
mkg-872	68	12	periodontal	periodontal	ADJ
mkg-872	68	13	diseases	disease	NOUN
mkg-872	68	14	,	,	PUNCT
mkg-872	68	15	identify	identify	VERB
mkg-872	68	16	antibiotic	antibiotic	ADJ
mkg-872	68	17	susceptibility	susceptibility	NOUN
mkg-872	68	18	of	of	ADP
mkg-872	68	19	infecting	infect	VERB
mkg-872	68	20	organisms	organism	NOUN
mkg-872	68	21	colonizing	colonize	VERB
mkg-872	68	22	diseases	disease	NOUN
mkg-872	68	23	sites	site	NOUN
mkg-872	68	24	,	,	PUNCT
mkg-872	68	25	and	and	CCONJ
mkg-872	68	26	predict	predict	VERB
mkg-872	68	27	diseases	disease	NOUN
mkg-872	68	28	activity.2–4,22–26	activity.2–4,22–26	ADJ
mkg-872	68	29	collagen	collagen	NOUN
mkg-872	68	30	degradation	degradation	NOUN
mkg-872	68	31	and	and	CCONJ
mkg-872	68	32	bone	bone	NOUN
mkg-872	68	33	turnover	turnover	NOUN
mkg-872	68	34	initially	initially	ADV
mkg-872	68	35	,	,	PUNCT
mkg-872	68	36	tissue	tissue	NOUN
mkg-872	68	37	degradation	degradation	NOUN
mkg-872	68	38	is	be	AUX
mkg-872	68	39	limited	limit	VERB
mkg-872	68	40	to	to	ADP
mkg-872	68	41	ephitelial	ephitelial	ADJ
mkg-872	68	42	cells	cell	NOUN
mkg-872	68	43	and	and	CCONJ
mkg-872	68	44	collagen	collagen	NOUN
mkg-872	68	45	fibers	fiber	NOUN
mkg-872	68	46	from	from	ADP
mkg-872	68	47	the	the	DET
mkg-872	68	48	connective	connective	ADJ
mkg-872	68	49	tissue	tissue	NOUN
mkg-872	68	50	.	.	PUNCT
mkg-872	69	1	later	later	ADV
mkg-872	69	2	on	on	ADV
mkg-872	69	3	,	,	PUNCT
mkg-872	69	4	the	the	DET
mkg-872	69	5	inflammatory	inflammatory	ADJ
mkg-872	69	6	process	process	NOUN
mkg-872	69	7	may	may	AUX
mkg-872	69	8	reach	reach	VERB
mkg-872	69	9	periodontal	periodontal	ADJ
mkg-872	69	10	supportive	supportive	ADJ
mkg-872	69	11	tissue	tissue	NOUN
mkg-872	69	12	and	and	CCONJ
mkg-872	69	13	leading	lead	VERB
mkg-872	69	14	to	to	ADP
mkg-872	69	15	bone	bone	NOUN
mkg-872	69	16	resorption.27	resorption.27	NOUN
mkg-872	69	17	collagen	collagen	NOUN
mkg-872	69	18	degradation	degradation	NOUN
mkg-872	69	19	products	product	NOUN
mkg-872	69	20	is	be	AUX
mkg-872	69	21	markers	marker	NOUN
mkg-872	69	22	of	of	ADP
mkg-872	69	23	bone	bone	NOUN
mkg-872	69	24	turnover	turnover	NOUN
mkg-872	69	25	in	in	ADP
mkg-872	69	26	multitude	multitude	NOUN
mkg-872	69	27	of	of	ADP
mkg-872	69	28	bone	bone	NOUN
mkg-872	69	29	resorptive	resorptive	ADJ
mkg-872	69	30	and	and	CCONJ
mkg-872	69	31	metabolic	metabolic	NOUN
mkg-872	69	32	diseases	disease	NOUN
mkg-872	69	33	.	.	PUNCT
mkg-872	70	1	the	the	DET
mkg-872	70	2	collagen	collagen	NOUN
mkg-872	70	3	degradative	degradative	ADJ
mkg-872	70	4	molecules	molecule	NOUN
mkg-872	70	5	is	be	AUX
mkg-872	70	6	in	in	ADP
mkg-872	70	7	periodontal	periodontal	NOUN
mkg-872	70	8	such	such	ADJ
mkg-872	70	9	as	as	ADP
mkg-872	70	10	pyridoline	pyridoline	NOUN
mkg-872	70	11	cross	cross	NOUN
mkg-872	70	12	-	-	NOUN
mkg-872	70	13	links	link	NOUN
mkg-872	70	14	(	(	PUNCT
mkg-872	70	15	including	include	VERB
mkg-872	70	16	pyridinoline	pyridinoline	NOUN
mkg-872	70	17	,	,	PUNCT
mkg-872	70	18	deoxypyridinoline	deoxypyridinoline	NOUN
mkg-872	70	19	,	,	PUNCT
mkg-872	70	20	n	n	CCONJ
mkg-872	70	21	-	-	PUNCT
mkg-872	70	22	telopeptides	telopeptide	NOUN
mkg-872	70	23	,	,	PUNCT
mkg-872	70	24	and	and	CCONJ
mkg-872	70	25	c	c	X
mkg-872	70	26	-	-	PUNCT
mkg-872	70	27	telopeptides	telopeptide	NOUN
mkg-872	70	28	)	)	PUNCT
mkg-872	70	29	.	.	PUNCT
mkg-872	71	1	pyridoline	pyridoline	PROPN
mkg-872	71	2	cross	cros	NOUN
mkg-872	71	3	-	-	ADJ
mkg-872	71	4	links	link	NOUN
mkg-872	71	5	considered	consider	VERB
mkg-872	71	6	as	as	ADP
mkg-872	71	7	specific	specific	ADJ
mkg-872	71	8	biomarkers	biomarker	NOUN
mkg-872	71	9	for	for	ADP
mkg-872	71	10	bone	bone	NOUN
mkg-872	71	11	resorption	resorption	NOUN
mkg-872	71	12	.	.	PUNCT
mkg-872	72	1	the	the	DET
mkg-872	72	2	pyridoline	pyridoline	NOUN
mkg-872	72	3	cross	cross	ADJ
mkg-872	72	4	-	-	ADJ
mkg-872	72	5	linked	link	VERB
mkg-872	72	6	carboxyterminal	carboxyterminal	ADJ
mkg-872	72	7	telopeptide	telopeptide	NOUN
mkg-872	72	8	of	of	ADP
mkg-872	72	9	type	type	NOUN
mkg-872	72	10	i	i	PRON
mkg-872	72	11	collagen	collagen	NOUN
mkg-872	72	12	(	(	PUNCT
mkg-872	72	13	ictp	ictp	ADJ
mkg-872	72	14	)	)	PUNCT
mkg-872	72	15	have	have	AUX
mkg-872	72	16	been	be	AUX
mkg-872	72	17	shown	show	VERB
mkg-872	72	18	to	to	PART
mkg-872	72	19	be	be	AUX
mkg-872	72	20	correlated	correlate	VERB
mkg-872	72	21	with	with	ADP
mkg-872	72	22	bone	bone	NOUN
mkg-872	72	23	resorptive	resorptive	ADJ
mkg-872	72	24	rate	rate	NOUN
mkg-872	72	25	in	in	ADP
mkg-872	72	26	several	several	ADJ
mkg-872	72	27	bone	bone	NOUN
mkg-872	72	28	metabolic	metabolic	NOUN
mkg-872	72	29	diseases	disease	NOUN
mkg-872	72	30	.	.	PUNCT
mkg-872	73	1	in	in	ADP
mkg-872	73	2	a	a	DET
mkg-872	73	3	cross	cross	ADJ
mkg-872	73	4	-	-	ADJ
mkg-872	73	5	sectional	sectional	ADJ
mkg-872	73	6	study	study	NOUN
mkg-872	73	7	evaluated	evaluate	VERB
mkg-872	73	8	the	the	DET
mkg-872	73	9	markers	marker	NOUN
mkg-872	73	10	of	of	ADP
mkg-872	73	11	bone	bone	NOUN
mkg-872	73	12	turnover	turnover	NOUN
mkg-872	73	13	are	be	AUX
mkg-872	73	14	ictp	ictp	ADJ
mkg-872	73	15	,	,	PUNCT
mkg-872	73	16	osteocalcin	osteocalcin	NOUN
mkg-872	73	17	and	and	CCONJ
mkg-872	73	18	osteonectin	osteonectin	VERB
mkg-872	73	19	in	in	ADP
mkg-872	73	20	stimulated	stimulated	ADJ
mkg-872	73	21	whole	whole	ADJ
mkg-872	73	22	saliva	saliva	NOUN
mkg-872	73	23	collected	collect	VERB
mkg-872	73	24	from	from	ADP
mkg-872	73	25	untreated	untreated	ADJ
mkg-872	73	26	dental	dental	ADJ
mkg-872	73	27	patients	patient	NOUN
mkg-872	73	28	.	.	PUNCT
mkg-872	74	1	increased	increase	VERB
mkg-872	74	2	levels	level	NOUN
mkg-872	74	3	of	of	ADP
mkg-872	74	4	salivary	salivary	ADJ
mkg-872	74	5	osteonectin	osteonectin	NOUN
mkg-872	74	6	were	be	AUX
mkg-872	74	7	associated	associate	VERB
mkg-872	74	8	with	with	ADP
mkg-872	74	9	less	less	ADJ
mkg-872	74	10	bone	bone	NOUN
mkg-872	74	11	loss.4,5,28–30	loss.4,5,28–30	PROPN
mkg-872	74	12	discussion	discussion	NOUN
mkg-872	74	13	a	a	DET
mkg-872	74	14	biomarker	biomarker	NOUN
mkg-872	74	15	or	or	CCONJ
mkg-872	74	16	biologic	biologic	NOUN
mkg-872	74	17	biomarker	biomarker	NOUN
mkg-872	74	18	is	be	AUX
mkg-872	74	19	substance	substance	NOUN
mkg-872	74	20	that	that	PRON
mkg-872	74	21	is	be	AUX
mkg-872	74	22	objectively	objectively	ADV
mkg-872	74	23	measured	measure	VERB
mkg-872	74	24	and	and	CCONJ
mkg-872	74	25	evaluated	evaluate	VERB
mkg-872	74	26	as	as	ADP
mkg-872	74	27	indicator	indicator	NOUN
mkg-872	74	28	of	of	ADP
mkg-872	74	29	normal	normal	ADJ
mkg-872	74	30	biologic	biologic	NOUN
mkg-872	74	31	processes	process	NOUN
mkg-872	74	32	,	,	PUNCT
mkg-872	74	33	pathogenic	pathogenic	ADJ
mkg-872	74	34	processes	process	NOUN
mkg-872	74	35	,	,	PUNCT
mkg-872	74	36	or	or	CCONJ
mkg-872	74	37	pharmacologic	pharmacologic	ADJ
mkg-872	74	38	responses	response	NOUN
mkg-872	74	39	to	to	ADP
mkg-872	74	40	therapeutic	therapeutic	ADJ
mkg-872	74	41	intervention.3	intervention.3	PROPN
mkg-872	74	42	whole	whole	ADJ
mkg-872	74	43	saliva	saliva	NOUN
mkg-872	74	44	is	be	AUX
mkg-872	74	45	important	important	ADJ
mkg-872	74	46	physiologic	physiologic	ADJ
mkg-872	74	47	fluid	fluid	NOUN
mkg-872	74	48	that	that	PRON
mkg-872	74	49	contain	contain	VERB
mkg-872	74	50	a	a	DET
mkg-872	74	51	highly	highly	ADV
mkg-872	74	52	complex	complex	ADJ
mkg-872	74	53	mixture	mixture	NOUN
mkg-872	74	54	of	of	ADP
mkg-872	74	55	substances	substance	NOUN
mkg-872	74	56	,	,	PUNCT
mkg-872	74	57	locally	locally	ADV
mkg-872	74	58	and	and	CCONJ
mkg-872	74	59	systemically	systemically	ADV
mkg-872	74	60	,	,	PUNCT
mkg-872	74	61	derived	derived	ADJ
mkg-872	74	62	markers	marker	NOUN
mkg-872	74	63	of	of	ADP
mkg-872	74	64	periodontal	periodontal	ADJ
mkg-872	74	65	and	and	CCONJ
mkg-872	74	66	systemic	systemic	ADJ
mkg-872	74	67	diseases	disease	NOUN
mkg-872	74	68	that	that	PRON
mkg-872	74	69	easily	easily	ADV
mkg-872	74	70	to	to	PART
mkg-872	74	71	collected	collect	VERB
mkg-872	74	72	.	.	PUNCT
mkg-872	75	1	so	so	ADV
mkg-872	75	2	,	,	PUNCT
mkg-872	75	3	it	it	PRON
mkg-872	75	4	may	may	AUX
mkg-872	75	5	offer	offer	VERB
mkg-872	75	6	the	the	DET
mkg-872	75	7	basis	basis	NOUN
mkg-872	75	8	for	for	ADP
mkg-872	75	9	a	a	DET
mkg-872	75	10	patient	patient	NOUN
mkg-872	75	11	-	-	PUNCT
mkg-872	75	12	specific	specific	ADJ
mkg-872	75	13	biomarker	biomarker	NOUN
mkg-872	75	14	assessment	assessment	NOUN
mkg-872	75	15	for	for	ADP
mkg-872	75	16	periodontitis	periodontitis	NOUN
mkg-872	75	17	and	and	CCONJ
mkg-872	75	18	other	other	ADJ
mkg-872	75	19	systemic	systemic	ADJ
mkg-872	75	20	diseases.1	diseases.1	NOUN
mkg-872	75	21	generally	generally	ADV
mkg-872	75	22	,	,	PUNCT
mkg-872	75	23	there	there	PRON
mkg-872	75	24	are	be	VERB
mkg-872	75	25	many	many	ADJ
mkg-872	75	26	clinicians	clinician	NOUN
mkg-872	75	27	reported	report	VERB
mkg-872	75	28	that	that	SCONJ
mkg-872	75	29	clinical	clinical	ADJ
mkg-872	75	30	parameters	parameter	NOUN
mkg-872	75	31	of	of	ADP
mkg-872	75	32	periodontal	periodontal	ADJ
mkg-872	75	33	disease	disease	NOUN
mkg-872	75	34	,	,	PUNCT
mkg-872	75	35	such	such	ADJ
mkg-872	75	36	as	as	ADP
mkg-872	75	37	probing	probe	VERB
mkg-872	75	38	depth	depth	NOUN
mkg-872	75	39	and	and	CCONJ
mkg-872	75	40	bleeding	bleed	VERB
mkg-872	75	41	on	on	ADP
mkg-872	75	42	probing	probe	VERB
mkg-872	75	43	were	be	AUX
mkg-872	75	44	limited	limit	VERB
mkg-872	75	45	in	in	ADP
mkg-872	75	46	their	their	PRON
mkg-872	75	47	ability	ability	NOUN
mkg-872	75	48	to	to	PART
mkg-872	75	49	predict	predict	VERB
mkg-872	75	50	the	the	DET
mkg-872	75	51	activity	activity	NOUN
mkg-872	75	52	of	of	ADP
mkg-872	75	53	periodontal	periodontal	ADJ
mkg-872	75	54	disease	disease	NOUN
mkg-872	75	55	.	.	PUNCT
mkg-872	76	1	therefore	therefore	ADV
mkg-872	76	2	,	,	PUNCT
mkg-872	76	3	saliva	saliva	NOUN
mkg-872	76	4	can	can	AUX
mkg-872	76	5	be	be	AUX
mkg-872	76	6	used	use	VERB
mkg-872	76	7	as	as	ADP
mkg-872	76	8	a	a	DET
mkg-872	76	9	non	non	ADJ
mkg-872	76	10	-	-	ADJ
mkg-872	76	11	invasive	invasive	ADJ
mkg-872	76	12	diagnostic	diagnostic	ADJ
mkg-872	76	13	fluid	fluid	NOUN
mkg-872	76	14	to	to	PART
mkg-872	76	15	measure	measure	VERB
mkg-872	76	16	biomarkers	biomarker	NOUN
mkg-872	76	17	released	release	VERB
mkg-872	76	18	during	during	ADP
mkg-872	76	19	disease	disease	NOUN
mkg-872	76	20	initiation	initiation	NOUN
mkg-872	76	21	and	and	CCONJ
mkg-872	76	22	progression	progression	NOUN
mkg-872	76	23	(	(	PUNCT
mkg-872	76	24	tabel	tabel	NOUN
mkg-872	76	25	1).4–8	1).4–8	PROPN
mkg-872	76	26	various	various	ADJ
mkg-872	76	27	assays	assay	NOUN
mkg-872	76	28	have	have	AUX
mkg-872	76	29	been	be	AUX
mkg-872	76	30	used	use	VERB
mkg-872	76	31	to	to	PART
mkg-872	76	32	detect	detect	VERB
mkg-872	76	33	the	the	DET
mkg-872	76	34	presence	presence	NOUN
mkg-872	76	35	of	of	ADP
mkg-872	76	36	specific	specific	ADJ
mkg-872	76	37	periodontal	periodontal	ADJ
mkg-872	76	38	pathogens	pathogen	NOUN
mkg-872	76	39	,	,	PUNCT
mkg-872	76	40	such	such	ADJ
mkg-872	76	41	as	as	ADP
mkg-872	76	42	culture	culture	NOUN
mkg-872	76	43	techniques	technique	NOUN
mkg-872	76	44	,	,	PUNCT
mkg-872	76	45	immunoflourescence	immunoflourescence	NOUN
mkg-872	76	46	,	,	PUNCT
mkg-872	76	47	and	and	CCONJ
mkg-872	76	48	dna	dna	PROPN
mkg-872	76	49	probe	probe	NOUN
mkg-872	76	50	technology	technology	NOUN
mkg-872	76	51	.	.	PUNCT
mkg-872	77	1	using	use	VERB
mkg-872	77	2	culture	culture	NOUN
mkg-872	77	3	techniques	technique	NOUN
mkg-872	77	4	requires	require	VERB
mkg-872	77	5	that	that	SCONJ
mkg-872	77	6	a	a	DET
mkg-872	77	7	viable	viable	ADJ
mkg-872	77	8	bacterial	bacterial	ADJ
mkg-872	77	9	sample	sample	NOUN
mkg-872	77	10	be	be	AUX
mkg-872	77	11	obtained	obtain	VERB
mkg-872	77	12	from	from	ADP
mkg-872	77	13	the	the	DET
mkg-872	77	14	patient	patient	NOUN
mkg-872	77	15	and	and	CCONJ
mkg-872	77	16	transferred	transfer	VERB
mkg-872	77	17	to	to	ADP
mkg-872	77	18	the	the	DET
mkg-872	77	19	laboratory	laboratory	NOUN
mkg-872	77	20	.	.	PUNCT
mkg-872	78	1	the	the	DET
mkg-872	78	2	sampling	sampling	NOUN
mkg-872	78	3	technique	technique	NOUN
mkg-872	78	4	for	for	ADP
mkg-872	78	5	these	these	DET
mkg-872	78	6	assays	assay	NOUN
mkg-872	78	7	is	be	AUX
mkg-872	78	8	relatively	relatively	ADV
mkg-872	78	9	noninvasive	noninvasive	ADJ
mkg-872	78	10	,	,	PUNCT
mkg-872	78	11	using	use	VERB
mkg-872	78	12	either	either	CCONJ
mkg-872	78	13	endodontic	endodontic	ADJ
mkg-872	78	14	paper	paper	NOUN
mkg-872	78	15	points	point	NOUN
mkg-872	78	16	or	or	CCONJ
mkg-872	78	17	a	a	DET
mkg-872	78	18	sterile	sterile	ADJ
mkg-872	78	19	curette	curette	NOUN
mkg-872	78	20	to	to	PART
mkg-872	78	21	obtain	obtain	VERB
mkg-872	78	22	bacteria	bacteria	NOUN
mkg-872	78	23	from	from	ADP
mkg-872	78	24	the	the	DET
mkg-872	78	25	subgingival	subgingival	PROPN
mkg-872	78	26	environment	environment	NOUN
mkg-872	78	27	,	,	PUNCT
mkg-872	78	28	include	include	VERB
mkg-872	78	29	b.	b.	PROPN
mkg-872	78	30	forsythus	forsythus	PROPN
mkg-872	78	31	,	,	PUNCT
mkg-872	78	32	p.	p.	PROPN
mkg-872	78	33	gingivalis	gingivalis	PROPN
mkg-872	78	34	,	,	PUNCT
mkg-872	78	35	t.	t.	PROPN
mkg-872	78	36	denticola	denticola	PROPN
mkg-872	78	37	,	,	PUNCT
mkg-872	78	38	and	and	CCONJ
mkg-872	78	39	a.	a.	NOUN
mkg-872	78	40	actinomycetemcomitans	actinomycetemcomitan	NOUN
mkg-872	78	41	as	as	ADP
mkg-872	78	42	periodontal	periodontal	ADJ
mkg-872	78	43	pathogen.22–26	pathogen.22–26	NOUN
mkg-872	78	44	the	the	DET
mkg-872	78	45	prevalence	prevalence	NOUN
mkg-872	78	46	of	of	ADP
mkg-872	78	47	bacteroides	bacteroide	NOUN
mkg-872	78	48	forsythus	forsythus	NOUN
mkg-872	78	49	in	in	ADP
mkg-872	78	50	severe	severe	ADJ
mkg-872	78	51	periodontitis	periodontitis	NOUN
mkg-872	78	52	patients	patient	NOUN
mkg-872	78	53	was	be	AUX
mkg-872	78	54	reported	report	VERB
mkg-872	78	55	significantly	significantly	ADV
mkg-872	78	56	higher	high	ADJ
mkg-872	78	57	than	than	ADP
mkg-872	78	58	table	table	NOUN
mkg-872	78	59	1	1	NUM
mkg-872	78	60	.	.	PUNCT
mkg-872	78	61	potential	potential	ADJ
mkg-872	78	62	predictors	predictor	NOUN
mkg-872	78	63	of	of	ADP
mkg-872	78	64	periodontal	periodontal	ADJ
mkg-872	78	65	disease	disease	NOUN
mkg-872	78	66	identified	identify	VERB
mkg-872	78	67	from	from	ADP
mkg-872	78	68	whole	whole	ADJ
mkg-872	78	69	saliva3,4	saliva3,4	ADJ
mkg-872	78	70	category	category	NOUN
mkg-872	78	71	mediator	mediator	NOUN
mkg-872	78	72	biomarkers	biomarker	VERB
mkg-872	78	73	microbial	microbial	ADJ
mkg-872	78	74	factors	factor	NOUN
mkg-872	78	75	b.	b.	NOUN
mkg-872	78	76	forsythus	forsythus	PROPN
mkg-872	78	77	,	,	PUNCT
mkg-872	78	78	p.	p.	PROPN
mkg-872	78	79	gingivalis	gingivalis	PROPN
mkg-872	78	80	,	,	PUNCT
mkg-872	78	81	a.	a.	PROPN
mkg-872	78	82	actino	actino	PROPN
mkg-872	78	83	-	-	PUNCT
mkg-872	78	84	mycetemcomitans	mycetemcomitan	NOUN
mkg-872	78	85	,	,	PUNCT
mkg-872	78	86	treponema	treponema	VERB
mkg-872	78	87	denticola	denticola	NOUN
mkg-872	78	88	host	host	NOUN
mkg-872	78	89	-	-	PUNCT
mkg-872	78	90	derived	derive	VERB
mkg-872	78	91	enzyme	enzyme	NOUN
mkg-872	78	92	alp	alp	NOUN
mkg-872	78	93	,	,	PUNCT
mkg-872	78	94	ast	ast	NOUN
mkg-872	78	95	,	,	PUNCT
mkg-872	78	96	elastase	elastase	VERB
mkg-872	78	97	inflammatory	inflammatory	ADJ
mkg-872	78	98	mediators	mediator	NOUN
mkg-872	78	99	&	&	CCONJ
mkg-872	78	100	host	host	NOUN
mkg-872	78	101	response	response	NOUN
mkg-872	78	102	modifier	modifier	NOUN
mkg-872	78	103	il-1β	il-1β	PROPN
mkg-872	78	104	;	;	PUNCT
mkg-872	78	105	il-6	il-6	NUM
mkg-872	78	106	,	,	PUNCT
mkg-872	78	107	tnf	tnf	PROPN
mkg-872	78	108	-	-	PUNCT
mkg-872	78	109	α	α	PROPN
mkg-872	78	110	,	,	PUNCT
mkg-872	78	111	mmp-8	mmp-8	ADV
mkg-872	78	112	connective	connective	ADJ
mkg-872	78	113	tissue	tissue	NOUN
mkg-872	78	114	breakdown	breakdown	NOUN
mkg-872	78	115	products	product	NOUN
mkg-872	78	116	collagen	collagen	NOUN
mkg-872	78	117	telopeptides	telopeptide	NOUN
mkg-872	78	118	(	(	PUNCT
mkg-872	78	119	itcp	itcp	NOUN
mkg-872	78	120	)	)	PUNCT
mkg-872	78	121	,	,	PUNCT
mkg-872	78	122	osteoprotegerin	osteoprotegerin	NOUN
mkg-872	78	123	(	(	PUNCT
mkg-872	78	124	opg	opg	PROPN
mkg-872	78	125	)	)	PUNCT
mkg-872	78	126	,	,	PUNCT
mkg-872	78	127	osteocalsin	osteocalsin	NOUN
mkg-872	78	128	,	,	PUNCT
mkg-872	78	129	osteonectin	osteonectin	NOUN
mkg-872	78	130	,	,	PUNCT
mkg-872	78	131	fibronectin	fibronectin	NOUN
mkg-872	78	132	fragments	fragment	NOUN
mkg-872	78	133	.	.	PUNCT
mkg-872	79	1	80	80	NUM
mkg-872	79	2	dent	dent	NOUN
mkg-872	79	3	.	.	PUNCT
mkg-872	80	1	j.	j.	PROPN
mkg-872	80	2	(	(	PUNCT
mkg-872	80	3	maj	maj	PROPN
mkg-872	80	4	.	.	PROPN
mkg-872	80	5	ked	ked	PROPN
mkg-872	80	6	.	.	PUNCT
mkg-872	81	1	gigi	gigi	PROPN
mkg-872	81	2	)	)	PUNCT
mkg-872	81	3	,	,	PUNCT
mkg-872	82	1	vol	vol	NOUN
mkg-872	82	2	.	.	PROPN
mkg-872	82	3	44	44	NUM
mkg-872	82	4	.	.	PUNCT
mkg-872	83	1	no	no	INTJ
mkg-872	83	2	.	.	NOUN
mkg-872	84	1	2	2	NUM
mkg-872	84	2	june	june	PROPN
mkg-872	84	3	2011	2011	NUM
mkg-872	84	4	:	:	PUNCT
mkg-872	84	5	77–81	77–81	NUM
mkg-872	84	6	in	in	ADP
mkg-872	84	7	those	those	PRON
mkg-872	84	8	with	with	ADP
mkg-872	84	9	healthy	healthy	ADJ
mkg-872	84	10	gingiva	gingiva	NOUN
mkg-872	84	11	or	or	CCONJ
mkg-872	84	12	gingivitis	gingivitis	NOUN
mkg-872	84	13	.	.	PUNCT
mkg-872	85	1	this	this	PRON
mkg-872	85	2	suggests	suggest	VERB
mkg-872	85	3	that	that	SCONJ
mkg-872	85	4	the	the	DET
mkg-872	85	5	presence	presence	NOUN
mkg-872	85	6	of	of	ADP
mkg-872	85	7	bacteroides	bacteroide	NOUN
mkg-872	85	8	forsythus	forsythus	NOUN
mkg-872	85	9	in	in	ADP
mkg-872	85	10	whole	whole	ADJ
mkg-872	85	11	saliva	saliva	NOUN
mkg-872	85	12	are	be	AUX
mkg-872	85	13	possible	possible	ADJ
mkg-872	85	14	to	to	PART
mkg-872	85	15	be	be	AUX
mkg-872	85	16	risk	risk	NOUN
mkg-872	85	17	indicators	indicator	NOUN
mkg-872	85	18	for	for	ADP
mkg-872	85	19	periodontal	periodontal	ADJ
mkg-872	85	20	disease	disease	NOUN
mkg-872	85	21	,	,	PUNCT
mkg-872	85	22	especially	especially	ADV
mkg-872	85	23	in	in	ADP
mkg-872	85	24	elderly	elderly	ADJ
mkg-872	85	25	patients.1,22–26	patients.1,22–26	ADJ
mkg-872	85	26	evaluating	evaluating	NOUN
mkg-872	85	27	utility	utility	NOUN
mkg-872	85	28	of	of	ADP
mkg-872	85	29	new	new	ADJ
mkg-872	85	30	laboratory	laboratory	NOUN
mkg-872	85	31	-	-	PUNCT
mkg-872	85	32	based	base	VERB
mkg-872	85	33	diagnostic	diagnostic	ADJ
mkg-872	85	34	methods	method	NOUN
mkg-872	85	35	must	must	AUX
mkg-872	85	36	present	present	VERB
mkg-872	85	37	either	either	CCONJ
mkg-872	85	38	the	the	DET
mkg-872	85	39	sensitivity	sensitivity	NOUN
mkg-872	85	40	and	and	CCONJ
mkg-872	85	41	specifi	specifi	PROPN
mkg-872	85	42	city	city	PROPN
mkg-872	85	43	of	of	ADP
mkg-872	85	44	test	test	NOUN
mkg-872	85	45	or	or	CCONJ
mkg-872	85	46	as	as	ADP
mkg-872	85	47	a	a	DET
mkg-872	85	48	measure	measure	NOUN
mkg-872	85	49	of	of	ADP
mkg-872	85	50	risk	risk	NOUN
mkg-872	85	51	periodontal	periodontal	ADJ
mkg-872	85	52	disease	disease	NOUN
mkg-872	85	53	.	.	PUNCT
mkg-872	86	1	sensitivity	sensitivity	NOUN
mkg-872	86	2	refers	refer	VERB
mkg-872	86	3	to	to	ADP
mkg-872	86	4	the	the	DET
mkg-872	86	5	ability	ability	NOUN
mkg-872	86	6	of	of	ADP
mkg-872	86	7	a	a	DET
mkg-872	86	8	diagnostic	diagnostic	ADJ
mkg-872	86	9	test	test	NOUN
mkg-872	86	10	to	to	PART
mkg-872	86	11	detect	detect	VERB
mkg-872	86	12	the	the	DET
mkg-872	86	13	presence	presence	NOUN
mkg-872	86	14	of	of	ADP
mkg-872	86	15	the	the	DET
mkg-872	86	16	disease	disease	NOUN
mkg-872	86	17	.	.	PUNCT
mkg-872	87	1	specifi	specifi	PROPN
mkg-872	87	2	city	city	PROPN
mkg-872	87	3	refers	refer	VERB
mkg-872	87	4	to	to	ADP
mkg-872	87	5	the	the	DET
mkg-872	87	6	ability	ability	NOUN
mkg-872	87	7	of	of	ADP
mkg-872	87	8	a	a	DET
mkg-872	87	9	diagnostic	diagnostic	ADJ
mkg-872	87	10	test	test	NOUN
mkg-872	87	11	to	to	PART
mkg-872	87	12	detect	detect	VERB
mkg-872	87	13	the	the	DET
mkg-872	87	14	absence	absence	NOUN
mkg-872	87	15	of	of	ADP
mkg-872	87	16	a	a	DET
mkg-872	87	17	disease	disease	NOUN
mkg-872	87	18	.	.	PUNCT
mkg-872	88	1	sensitivity	sensitivity	NOUN
mkg-872	88	2	and	and	CCONJ
mkg-872	88	3	specifi	specifi	PROPN
mkg-872	88	4	city	city	PROPN
mkg-872	88	5	tend	tend	VERB
mkg-872	88	6	to	to	PART
mkg-872	88	7	be	be	AUX
mkg-872	88	8	inversely	inversely	ADV
mkg-872	88	9	related	relate	VERB
mkg-872	88	10	.	.	PUNCT
mkg-872	89	1	the	the	DET
mkg-872	89	2	goal	goal	NOUN
mkg-872	89	3	of	of	ADP
mkg-872	89	4	ideal	ideal	ADJ
mkg-872	89	5	test	test	NOUN
mkg-872	89	6	for	for	ADP
mkg-872	89	7	periodontal	periodontal	ADJ
mkg-872	89	8	disease	disease	NOUN
mkg-872	89	9	that	that	PRON
mkg-872	89	10	would	would	AUX
mkg-872	89	11	be	be	AUX
mkg-872	89	12	able	able	ADJ
mkg-872	89	13	to	to	PART
mkg-872	89	14	predict	predict	VERB
mkg-872	89	15	which	which	DET
mkg-872	89	16	patients	patient	NOUN
mkg-872	89	17	will	will	AUX
mkg-872	89	18	experience	experience	VERB
mkg-872	89	19	attachment	attachment	NOUN
mkg-872	89	20	loss	loss	NOUN
mkg-872	89	21	(	(	PUNCT
mkg-872	89	22	“	"	PUNCT
mkg-872	89	23	active	active	ADJ
mkg-872	89	24	”	"	PUNCT
mkg-872	89	25	periodontal	periodontal	ADJ
mkg-872	89	26	disease	disease	NOUN
mkg-872	89	27	)	)	PUNCT
mkg-872	89	28	in	in	ADP
mkg-872	89	29	the	the	DET
mkg-872	89	30	near	near	ADJ
mkg-872	89	31	future	future	NOUN
mkg-872	89	32	and	and	CCONJ
mkg-872	89	33	to	to	PART
mkg-872	89	34	predict	predict	VERB
mkg-872	89	35	which	which	DET
mkg-872	89	36	teeth	tooth	NOUN
mkg-872	89	37	or	or	CCONJ
mkg-872	89	38	which	which	PRON
mkg-872	89	39	sites	site	NOUN
mkg-872	89	40	will	will	AUX
mkg-872	89	41	experience	experience	VERB
mkg-872	89	42	attachment	attachment	ADJ
mkg-872	89	43	loss	loss	NOUN
mkg-872	89	44	in	in	ADP
mkg-872	89	45	the	the	DET
mkg-872	89	46	near	near	ADJ
mkg-872	89	47	future	future	NOUN
mkg-872	89	48	.	.	PUNCT
mkg-872	90	1	in	in	ADP
mkg-872	90	2	addition	addition	NOUN
mkg-872	90	3	to	to	ADP
mkg-872	90	4	predicting	predict	VERB
mkg-872	90	5	which	which	PRON
mkg-872	90	6	patients	patient	NOUN
mkg-872	90	7	or	or	CCONJ
mkg-872	90	8	sites	site	NOUN
mkg-872	90	9	are	be	AUX
mkg-872	90	10	at	at	ADP
mkg-872	90	11	higher	high	ADJ
mkg-872	90	12	risk	risk	NOUN
mkg-872	90	13	of	of	ADP
mkg-872	90	14	becoming	become	VERB
mkg-872	90	15	active	active	ADJ
mkg-872	90	16	,	,	PUNCT
mkg-872	90	17	diagnostic	diagnostic	ADJ
mkg-872	90	18	tests	test	NOUN
mkg-872	90	19	can	can	AUX
mkg-872	90	20	be	be	AUX
mkg-872	90	21	used	use	VERB
mkg-872	90	22	to	to	PART
mkg-872	90	23	categorize	categorize	VERB
mkg-872	90	24	patients	patient	NOUN
mkg-872	90	25	into	into	ADP
mkg-872	90	26	different	different	ADJ
mkg-872	90	27	disease	disease	NOUN
mkg-872	90	28	categories	category	NOUN
mkg-872	90	29	;	;	PUNCT
mkg-872	90	30	ie	ie	X
mkg-872	90	31	,	,	PUNCT
mkg-872	90	32	aggressive	aggressive	ADJ
mkg-872	90	33	or	or	CCONJ
mkg-872	90	34	chronic	chronic	ADJ
mkg-872	90	35	periodontitis	periodontitis	NOUN
mkg-872	90	36	,	,	PUNCT
mkg-872	90	37	or	or	CCONJ
mkg-872	90	38	response	response	NOUN
mkg-872	90	39	or	or	CCONJ
mkg-872	90	40	no	no	DET
mkg-872	90	41	response	response	NOUN
mkg-872	90	42	to	to	ADP
mkg-872	90	43	treatment	treatment	NOUN
mkg-872	90	44	.	.	PUNCT
mkg-872	91	1	besides	besides	SCONJ
mkg-872	91	2	,	,	PUNCT
mkg-872	91	3	it	it	PRON
mkg-872	91	4	can	can	AUX
mkg-872	91	5	also	also	ADV
mkg-872	91	6	be	be	AUX
mkg-872	91	7	used	use	VERB
mkg-872	91	8	to	to	PART
mkg-872	91	9	determine	determine	VERB
mkg-872	91	10	the	the	DET
mkg-872	91	11	prognoses	prognosis	NOUN
mkg-872	91	12	of	of	ADP
mkg-872	91	13	treatment.27	treatment.27	PROPN
mkg-872	91	14	in	in	ADP
mkg-872	91	15	addition	addition	NOUN
mkg-872	91	16	,	,	PUNCT
mkg-872	91	17	an	an	DET
mkg-872	91	18	ideal	ideal	ADJ
mkg-872	91	19	periodontal	periodontal	ADJ
mkg-872	91	20	diagnostic	diagnostic	ADJ
mkg-872	91	21	test	test	NOUN
mkg-872	91	22	would	would	AUX
mkg-872	91	23	have	have	VERB
mkg-872	91	24	to	to	PART
mkg-872	91	25	be	be	AUX
mkg-872	91	26	economically	economically	ADV
mkg-872	91	27	feasible	feasible	ADJ
mkg-872	91	28	and	and	CCONJ
mkg-872	91	29	easy	easy	ADJ
mkg-872	91	30	to	to	PART
mkg-872	91	31	use	use	VERB
mkg-872	91	32	.	.	PUNCT
mkg-872	92	1	analysis	analysis	NOUN
mkg-872	92	2	of	of	ADP
mkg-872	92	3	the	the	DET
mkg-872	92	4	host	host	NOUN
mkg-872	92	5	responses	response	NOUN
mkg-872	92	6	to	to	ADP
mkg-872	92	7	periodontal	periodontal	ADJ
mkg-872	92	8	disease	disease	NOUN
mkg-872	92	9	for	for	ADP
mkg-872	92	10	diagnostic	diagnostic	ADJ
mkg-872	92	11	purposes	purpose	NOUN
mkg-872	92	12	has	have	AUX
mkg-872	92	13	involved	involve	VERB
mkg-872	92	14	the	the	DET
mkg-872	92	15	quantifi	quantifi	ADJ
mkg-872	92	16	cation	cation	NOUN
mkg-872	92	17	of	of	ADP
mkg-872	92	18	specifi	specifi	PROPN
mkg-872	92	19	c	c	PROPN
mkg-872	92	20	host	host	NOUN
mkg-872	92	21	-	-	PUNCT
mkg-872	92	22	derived	derive	VERB
mkg-872	92	23	molecules	molecule	NOUN
mkg-872	92	24	within	within	ADP
mkg-872	92	25	gingival	gingival	NOUN
mkg-872	92	26	crevicular	crevicular	NOUN
mkg-872	92	27	fl	fl	ADP
mkg-872	92	28	uid	uid	ADJ
mkg-872	92	29	,	,	PUNCT
mkg-872	92	30	serum	serum	NOUN
mkg-872	92	31	,	,	PUNCT
mkg-872	92	32	or	or	CCONJ
mkg-872	92	33	saliva	saliva	NOUN
mkg-872	92	34	.	.	PUNCT
mkg-872	93	1	in	in	ADP
mkg-872	93	2	whole	whole	ADJ
mkg-872	93	3	saliva	saliva	NOUN
mkg-872	93	4	,	,	PUNCT
mkg-872	93	5	ast	ast	ADJ
mkg-872	93	6	,	,	PUNCT
mkg-872	93	7	alt	alt	ADJ
mkg-872	93	8	,	,	PUNCT
mkg-872	93	9	ggt	ggt	NOUN
mkg-872	93	10	,	,	PUNCT
mkg-872	93	11	ldh	ldh	PROPN
mkg-872	93	12	,	,	PUNCT
mkg-872	93	13	ck	ck	PROPN
mkg-872	93	14	,	,	PUNCT
mkg-872	93	15	alp	alp	PROPN
mkg-872	93	16	,	,	PUNCT
mkg-872	93	17	acp	acp	PROPN
mkg-872	93	18	are	be	AUX
mkg-872	93	19	intra	intra	ADJ
mkg-872	93	20	cellular	cellular	ADJ
mkg-872	93	21	enzymes	enzyme	NOUN
mkg-872	93	22	that	that	PRON
mkg-872	93	23	have	have	VERB
mkg-872	93	24	enzymatic	enzymatic	ADJ
mkg-872	93	25	activity	activity	NOUN
mkg-872	93	26	refl	refl	NOUN
mkg-872	93	27	ect	ect	VERB
mkg-872	93	28	metabolic	metabolic	NOUN
mkg-872	93	29	changes	change	NOUN
mkg-872	93	30	in	in	ADP
mkg-872	93	31	the	the	DET
mkg-872	93	32	gingiva	gingiva	NOUN
mkg-872	93	33	and	and	CCONJ
mkg-872	93	34	periodontium	periodontium	NOUN
mkg-872	93	35	infl	infl	PROPN
mkg-872	93	36	amation.1	amation.1	ADP
mkg-872	93	37	those	those	DET
mkg-872	93	38	enzyme	enzyme	NOUN
mkg-872	93	39	used	use	VERB
mkg-872	93	40	to	to	PART
mkg-872	93	41	measure	measure	VERB
mkg-872	93	42	a	a	DET
mkg-872	93	43	death	death	NOUN
mkg-872	93	44	cell	cell	NOUN
mkg-872	93	45	.	.	PUNCT
mkg-872	94	1	the	the	DET
mkg-872	94	2	elevation	elevation	NOUN
mkg-872	94	3	of	of	ADP
mkg-872	94	4	ast	ast	NOUN
mkg-872	94	5	levels	level	NOUN
mkg-872	94	6	was	be	AUX
mkg-872	94	7	associated	associate	VERB
mkg-872	94	8	with	with	ADP
mkg-872	94	9	a	a	DET
mkg-872	94	10	9	9	NUM
mkg-872	94	11	to	to	PART
mkg-872	94	12	16	16	NUM
mkg-872	94	13	times	time	NOUN
mkg-872	94	14	greater	great	ADJ
mkg-872	94	15	risk	risk	NOUN
mkg-872	94	16	of	of	ADP
mkg-872	94	17	experiencing	experience	VERB
mkg-872	94	18	active	active	ADJ
mkg-872	94	19	periodontal	periodontal	ADJ
mkg-872	94	20	tissue	tissue	NOUN
mkg-872	94	21	destruction	destruction	NOUN
mkg-872	94	22	.	.	PUNCT
mkg-872	95	1	whereas	whereas	ADV
mkg-872	95	2	,	,	PUNCT
mkg-872	95	3	alp	alp	PROPN
mkg-872	95	4	shown	show	VERB
mkg-872	95	5	a	a	DET
mkg-872	95	6	remarkably	remarkably	ADV
mkg-872	95	7	increased	increase	VERB
mkg-872	95	8	activity	activity	NOUN
mkg-872	95	9	in	in	ADP
mkg-872	95	10	acute	acute	ADJ
mkg-872	95	11	phase	phase	NOUN
mkg-872	95	12	of	of	ADP
mkg-872	95	13	periodontal	periodontal	ADJ
mkg-872	95	14	disease	disease	NOUN
mkg-872	95	15	,	,	PUNCT
mkg-872	95	16	and	and	CCONJ
mkg-872	95	17	restored	restore	VERB
mkg-872	95	18	to	to	ADP
mkg-872	95	19	the	the	DET
mkg-872	95	20	value	value	NOUN
mkg-872	95	21	in	in	ADP
mkg-872	95	22	healthy	healthy	ADJ
mkg-872	95	23	person.18,19	person.18,19	NOUN
mkg-872	95	24	the	the	DET
mkg-872	95	25	other	other	ADJ
mkg-872	95	26	site	site	NOUN
mkg-872	95	27	,	,	PUNCT
mkg-872	95	28	elastase	elastase	NOUN
mkg-872	95	29	found	find	VERB
mkg-872	95	30	in	in	ADP
mkg-872	95	31	the	the	DET
mkg-872	95	32	lysosomal	lysosomal	ADJ
mkg-872	95	33	granules	granule	NOUN
mkg-872	95	34	of	of	ADP
mkg-872	95	35	polymorphonuclear	polymorphonuclear	NOUN
mkg-872	95	36	leukocytes	leukocyte	NOUN
mkg-872	95	37	(	(	PUNCT
mkg-872	95	38	pmns	pmn	NOUN
mkg-872	95	39	)	)	PUNCT
mkg-872	95	40	.	.	PUNCT
mkg-872	96	1	also	also	ADV
mkg-872	96	2	elevated	elevate	VERB
mkg-872	96	3	in	in	ADP
mkg-872	96	4	patients	patient	NOUN
mkg-872	96	5	with	with	ADP
mkg-872	96	6	active	active	ADJ
mkg-872	96	7	periodontal	periodontal	ADJ
mkg-872	96	8	disease.9,18–21	disease.9,18–21	NOUN
mkg-872	96	9	alp	alp	PROPN
mkg-872	96	10	is	be	AUX
mkg-872	96	11	a	a	DET
mkg-872	96	12	membrane	membrane	NOUN
mkg-872	96	13	-	-	PUNCT
mkg-872	96	14	bound	bind	VERB
mkg-872	96	15	glycoprotein	glycoprotein	NOUN
mkg-872	96	16	produced	produce	VERB
mkg-872	96	17	by	by	ADP
mkg-872	96	18	many	many	ADJ
mkg-872	96	19	cells	cell	NOUN
mkg-872	96	20	,	,	PUNCT
mkg-872	96	21	such	such	ADJ
mkg-872	96	22	as	as	ADP
mkg-872	96	23	pmns	pmn	NOUN
mkg-872	96	24	leukocytes	leukocyte	NOUN
mkg-872	96	25	during	during	ADP
mkg-872	96	26	infl	infl	PROPN
mkg-872	96	27	ammation	ammation	PROPN
mkg-872	96	28	,	,	PUNCT
mkg-872	96	29	osteoblasts	osteoblast	NOUN
mkg-872	96	30	,	,	PUNCT
mkg-872	96	31	macrophages	macrophage	NOUN
mkg-872	96	32	,	,	PUNCT
mkg-872	96	33	and	and	CCONJ
mkg-872	96	34	periodontal	periodontal	ADJ
mkg-872	96	35	ligament	ligament	NOUN
mkg-872	96	36	fibroblasts	fibroblast	NOUN
mkg-872	96	37	,	,	PUNCT
mkg-872	96	38	during	during	ADP
mkg-872	96	39	bone	bone	NOUN
mkg-872	96	40	formation	formation	NOUN
mkg-872	96	41	and	and	CCONJ
mkg-872	96	42	periodontal	periodontal	ADJ
mkg-872	96	43	regeneration	regeneration	NOUN
mkg-872	96	44	respectively	respectively	ADV
mkg-872	96	45	,	,	PUNCT
mkg-872	96	46	within	within	ADP
mkg-872	96	47	the	the	DET
mkg-872	96	48	area	area	NOUN
mkg-872	96	49	of	of	ADP
mkg-872	96	50	the	the	DET
mkg-872	96	51	periodontium	periodontium	NOUN
mkg-872	96	52	and	and	CCONJ
mkg-872	96	53	gingival	gingival	NOUN
mkg-872	96	54	crevice	crevice	NOUN
mkg-872	96	55	.	.	PUNCT
mkg-872	97	1	the	the	DET
mkg-872	97	2	alp	alp	PROPN
mkg-872	97	3	activity	activity	NOUN
mkg-872	97	4	was	be	AUX
mkg-872	97	5	found	find	VERB
mkg-872	97	6	highest	high	ADJ
mkg-872	97	7	in	in	ADP
mkg-872	97	8	osteoblasts	osteoblast	NOUN
mkg-872	97	9	,	,	PUNCT
mkg-872	97	10	moderate	moderate	ADJ
mkg-872	97	11	in	in	ADP
mkg-872	97	12	periodontal	periodontal	ADJ
mkg-872	97	13	ligament	ligament	NOUN
mkg-872	97	14	(	(	PUNCT
mkg-872	97	15	pdl	pdl	NOUN
mkg-872	97	16	)	)	PUNCT
mkg-872	97	17	fi	fi	NOUN
mkg-872	97	18	broblasts	broblast	NOUN
mkg-872	97	19	,	,	PUNCT
mkg-872	97	20	and	and	CCONJ
mkg-872	97	21	lowest	low	ADJ
mkg-872	97	22	in	in	ADP
mkg-872	97	23	gingival	gingival	NOUN
mkg-872	97	24	fi	fi	NOUN
mkg-872	97	25	broblasts	broblast	NOUN
mkg-872	97	26	.	.	PUNCT
mkg-872	98	1	the	the	DET
mkg-872	98	2	enzyme	enzyme	NOUN
mkg-872	98	3	alp	alp	PROPN
mkg-872	98	4	plays	play	VERB
mkg-872	98	5	a	a	DET
mkg-872	98	6	role	role	NOUN
mkg-872	98	7	in	in	ADP
mkg-872	98	8	bone	bone	NOUN
mkg-872	98	9	metabolism	metabolism	NOUN
mkg-872	98	10	and	and	CCONJ
mkg-872	98	11	bone	bone	NOUN
mkg-872	98	12	mineralization	mineralization	NOUN
mkg-872	98	13	by	by	ADP
mkg-872	98	14	releasing	release	VERB
mkg-872	98	15	an	an	DET
mkg-872	98	16	organic	organic	ADJ
mkg-872	98	17	phosphate	phosphate	NOUN
mkg-872	98	18	that	that	PRON
mkg-872	98	19	contributes	contribute	VERB
mkg-872	98	20	to	to	ADP
mkg-872	98	21	the	the	DET
mkg-872	98	22	deposition	deposition	NOUN
mkg-872	98	23	of	of	ADP
mkg-872	98	24	calcium	calcium	NOUN
mkg-872	98	25	phosphate	phosphate	NOUN
mkg-872	98	26	complexes	complex	NOUN
mkg-872	98	27	into	into	ADP
mkg-872	98	28	the	the	DET
mkg-872	98	29	osteoid	osteoid	NOUN
mkg-872	98	30	matrix	matrix	NOUN
mkg-872	98	31	.	.	PUNCT
mkg-872	99	1	alp	alp	PROPN
mkg-872	99	2	might	might	AUX
mkg-872	99	3	also	also	ADV
mkg-872	99	4	promote	promote	VERB
mkg-872	99	5	mineralization	mineralization	NOUN
mkg-872	99	6	by	by	ADP
mkg-872	99	7	hydrolyzing	hydrolyze	VERB
mkg-872	99	8	inorganic	inorganic	ADJ
mkg-872	99	9	pyrophosphate	pyrophosphate	NOUN
mkg-872	99	10	,	,	PUNCT
mkg-872	99	11	a	a	DET
mkg-872	99	12	potent	potent	ADJ
mkg-872	99	13	inhibitor	inhibitor	NOUN
mkg-872	99	14	of	of	ADP
mkg-872	99	15	hydroxyapatite	hydroxyapatite	NOUN
mkg-872	99	16	crystal	crystal	NOUN
mkg-872	99	17	formation	formation	NOUN
mkg-872	99	18	and	and	CCONJ
mkg-872	99	19	dissolution	dissolution	NOUN
mkg-872	99	20	,	,	PUNCT
mkg-872	99	21	within	within	ADP
mkg-872	99	22	the	the	DET
mkg-872	99	23	extra	extra	ADJ
mkg-872	99	24	cellular	cellular	ADJ
mkg-872	99	25	calcifying	calcifying	NOUN
mkg-872	99	26	matrix	matrix	NOUN
mkg-872	99	27	vesicles	vesicle	NOUN
mkg-872	99	28	.	.	PUNCT
mkg-872	100	1	in	in	ADP
mkg-872	100	2	the	the	DET
mkg-872	100	3	periodontium	periodontium	NOUN
mkg-872	100	4	,	,	PUNCT
mkg-872	100	5	alp	alp	PROPN
mkg-872	100	6	is	be	AUX
mkg-872	100	7	very	very	ADV
mkg-872	100	8	important	important	ADJ
mkg-872	100	9	enzyme	enzyme	NOUN
mkg-872	100	10	as	as	SCONJ
mkg-872	100	11	it	it	PRON
mkg-872	100	12	is	be	AUX
mkg-872	100	13	part	part	NOUN
mkg-872	100	14	of	of	ADP
mkg-872	100	15	normal	normal	ADJ
mkg-872	100	16	turnover	turnover	NOUN
mkg-872	100	17	of	of	ADP
mkg-872	100	18	periodontal	periodontal	ADJ
mkg-872	100	19	ligament	ligament	NOUN
mkg-872	100	20	,	,	PUNCT
mkg-872	100	21	root	root	NOUN
mkg-872	100	22	cementum	cementum	NOUN
mkg-872	100	23	,	,	PUNCT
mkg-872	100	24	and	and	CCONJ
mkg-872	100	25	maintenance	maintenance	NOUN
mkg-872	100	26	of	of	ADP
mkg-872	100	27	bone	bone	NOUN
mkg-872	100	28	homeostasis	homeostasis	NOUN
mkg-872	100	29	.	.	PUNCT
mkg-872	101	1	some	some	DET
mkg-872	101	2	studies	study	NOUN
mkg-872	101	3	have	have	AUX
mkg-872	101	4	shown	show	VERB
mkg-872	101	5	a	a	DET
mkg-872	101	6	remarkably	remarkably	ADV
mkg-872	101	7	increased	increase	VERB
mkg-872	101	8	activity	activity	NOUN
mkg-872	101	9	of	of	ADP
mkg-872	101	10	alp	alp	NOUN
mkg-872	101	11	in	in	ADP
mkg-872	101	12	the	the	DET
mkg-872	101	13	acute	acute	ADJ
mkg-872	101	14	and	and	CCONJ
mkg-872	101	15	chronic	chronic	ADJ
mkg-872	101	16	phase	phase	NOUN
mkg-872	101	17	of	of	ADP
mkg-872	101	18	periodontal	periodontal	ADJ
mkg-872	101	19	disease	disease	NOUN
mkg-872	101	20	,	,	PUNCT
mkg-872	101	21	and	and	CCONJ
mkg-872	101	22	after	after	ADP
mkg-872	101	23	the	the	DET
mkg-872	101	24	periodontal	periodontal	ADJ
mkg-872	101	25	and	and	CCONJ
mkg-872	101	26	orthodontic	orthodontic	ADJ
mkg-872	101	27	therapy	therapy	NOUN
mkg-872	101	28	.	.	PUNCT
mkg-872	102	1	the	the	DET
mkg-872	102	2	periodontal	periodontal	ADJ
mkg-872	102	3	destruction	destruction	NOUN
mkg-872	102	4	such	such	ADJ
mkg-872	102	5	as	as	ADP
mkg-872	102	6	alveolar	alveolar	ADJ
mkg-872	102	7	bone	bone	NOUN
mkg-872	102	8	loss	loss	NOUN
mkg-872	102	9	,	,	PUNCT
mkg-872	102	10	periodontal	periodontal	ADJ
mkg-872	102	11	pockets	pocket	NOUN
mkg-872	102	12	,	,	PUNCT
mkg-872	102	13	gingival	gingival	NOUN
mkg-872	102	14	bleeding	bleeding	NOUN
mkg-872	102	15	and	and	CCONJ
mkg-872	102	16	suppuration	suppuration	NOUN
mkg-872	102	17	are	be	AUX
mkg-872	102	18	related	relate	VERB
mkg-872	102	19	to	to	ADP
mkg-872	102	20	higher	high	ADJ
mkg-872	102	21	alp	alp	NOUN
mkg-872	102	22	and	and	CCONJ
mkg-872	102	23	ast	ast	NOUN
mkg-872	102	24	levels	level	NOUN
mkg-872	102	25	in	in	ADP
mkg-872	102	26	saliva	saliva	NOUN
mkg-872	102	27	.	.	PUNCT
mkg-872	103	1	ast	ast	PROPN
mkg-872	103	2	is	be	AUX
mkg-872	103	3	a	a	DET
mkg-872	103	4	tissue	tissue	NOUN
mkg-872	103	5	destruction	destruction	NOUN
mkg-872	103	6	biomarker	biomarker	NOUN
mkg-872	103	7	released	release	VERB
mkg-872	103	8	from	from	ADP
mkg-872	103	9	necrotic	necrotic	ADJ
mkg-872	103	10	cells	cell	NOUN
mkg-872	103	11	in	in	ADP
mkg-872	103	12	gcf	gcf	PROPN
mkg-872	103	13	,	,	PUNCT
mkg-872	103	14	is	be	AUX
mkg-872	103	15	associated	associate	VERB
mkg-872	103	16	with	with	ADP
mkg-872	103	17	periodontitis	periodontitis	NOUN
mkg-872	103	18	severity	severity	NOUN
mkg-872	103	19	.	.	PUNCT
mkg-872	104	1	8,18–21	8,18–21	NUM
mkg-872	104	2	cytokines	cytokine	NOUN
mkg-872	104	3	are	be	AUX
mkg-872	104	4	molecules	molecule	NOUN
mkg-872	104	5	that	that	PRON
mkg-872	104	6	modulate	modulate	VERB
mkg-872	104	7	the	the	DET
mkg-872	104	8	function	function	NOUN
mkg-872	104	9	of	of	ADP
mkg-872	104	10	a	a	DET
mkg-872	104	11	wide	wide	ADJ
mkg-872	104	12	variety	variety	NOUN
mkg-872	104	13	of	of	ADP
mkg-872	104	14	cells	cell	NOUN
mkg-872	104	15	and	and	CCONJ
mkg-872	104	16	are	be	AUX
mkg-872	104	17	involved	involve	VERB
mkg-872	104	18	in	in	ADP
mkg-872	104	19	regulating	regulate	VERB
mkg-872	104	20	the	the	DET
mkg-872	104	21	immune	immune	NOUN
mkg-872	104	22	and	and	CCONJ
mkg-872	104	23	infl	infl	PROPN
mkg-872	104	24	ammatory	ammatory	NOUN
mkg-872	104	25	response	response	NOUN
mkg-872	104	26	.	.	PUNCT
mkg-872	105	1	pro	pro	ADJ
mkg-872	105	2	-	-	ADJ
mkg-872	105	3	infl	infl	ADJ
mkg-872	105	4	ammatory	ammatory	NOUN
mkg-872	105	5	cytokine	cytokine	NOUN
mkg-872	105	6	with	with	ADP
mkg-872	105	7	the	the	DET
mkg-872	105	8	most	most	ADJ
mkg-872	105	9	promise	promise	NOUN
mkg-872	105	10	for	for	ADP
mkg-872	105	11	diagnostic	diagnostic	ADJ
mkg-872	105	12	testing	testing	NOUN
mkg-872	105	13	is	be	AUX
mkg-872	105	14	known	know	VERB
mkg-872	105	15	as	as	ADP
mkg-872	105	16	il-1β	il-1β	PROPN
mkg-872	105	17	,	,	PUNCT
mkg-872	105	18	il-6	il-6	NUM
mkg-872	105	19	and	and	CCONJ
mkg-872	105	20	tnf	tnf	PROPN
mkg-872	105	21	-	-	PUNCT
mkg-872	105	22	α	α	PROPN
mkg-872	105	23	.	.	PUNCT
mkg-872	106	1	il-1β	il-1β	PROPN
mkg-872	106	2	and	and	CCONJ
mkg-872	106	3	tnf	tnf	PROPN
mkg-872	106	4	-	-	PUNCT
mkg-872	106	5	α	α	PROPN
mkg-872	106	6	are	be	AUX
mkg-872	106	7	is	be	AUX
mkg-872	106	8	produced	produce	VERB
mkg-872	106	9	by	by	ADP
mkg-872	106	10	a	a	DET
mkg-872	106	11	wide	wide	ADJ
mkg-872	106	12	variety	variety	NOUN
mkg-872	106	13	of	of	ADP
mkg-872	106	14	cell	cell	NOUN
mkg-872	106	15	types	type	NOUN
mkg-872	106	16	(	(	PUNCT
mkg-872	106	17	macrophages	macrophage	NOUN
mkg-872	106	18	,	,	PUNCT
mkg-872	106	19	fibroblasts	fibroblast	NOUN
mkg-872	106	20	,	,	PUNCT
mkg-872	106	21	keratinocytes	keratinocyte	NOUN
mkg-872	106	22	,	,	PUNCT
mkg-872	106	23	and	and	CCONJ
mkg-872	106	24	pmns	pmn	NOUN
mkg-872	106	25	leucocytes	leucocyte	NOUN
mkg-872	106	26	)	)	PUNCT
mkg-872	106	27	,	,	PUNCT
mkg-872	106	28	but	but	CCONJ
mkg-872	106	29	the	the	DET
mkg-872	106	30	primary	primary	ADJ
mkg-872	106	31	producer	producer	NOUN
mkg-872	106	32	of	of	ADP
mkg-872	106	33	il-1β	il-1β	PROPN
mkg-872	106	34	in	in	ADP
mkg-872	106	35	the	the	DET
mkg-872	106	36	gingival	gingival	NOUN
mkg-872	106	37	tissues	tissue	NOUN
mkg-872	106	38	is	be	AUX
mkg-872	106	39	the	the	DET
mkg-872	106	40	macrophage.4,5,13–17	macrophage.4,5,13–17	PROPN
mkg-872	106	41	il-1β	il-1β	PROPN
mkg-872	106	42	has	have	VERB
mkg-872	106	43	a	a	DET
mkg-872	106	44	number	number	NOUN
mkg-872	106	45	of	of	ADP
mkg-872	106	46	biologic	biologic	NOUN
mkg-872	106	47	effects	effect	NOUN
mkg-872	106	48	,	,	PUNCT
mkg-872	106	49	including	include	VERB
mkg-872	106	50	initiating	initiate	VERB
mkg-872	106	51	the	the	DET
mkg-872	106	52	acute	acute	ADJ
mkg-872	106	53	phase	phase	NOUN
mkg-872	106	54	response	response	NOUN
mkg-872	106	55	to	to	ADP
mkg-872	106	56	infection	infection	NOUN
mkg-872	106	57	.	.	PUNCT
mkg-872	107	1	however	however	ADV
mkg-872	107	2	,	,	PUNCT
mkg-872	107	3	in	in	ADP
mkg-872	107	4	the	the	DET
mkg-872	107	5	periodontium	periodontium	NOUN
mkg-872	107	6	,	,	PUNCT
mkg-872	107	7	it	it	PRON
mkg-872	107	8	likely	likely	ADV
mkg-872	107	9	functions	function	NOUN
mkg-872	107	10	to	to	PART
mkg-872	107	11	mediate	mediate	VERB
mkg-872	107	12	connective	connective	ADJ
mkg-872	107	13	tissue	tissue	NOUN
mkg-872	107	14	destruction	destruction	NOUN
mkg-872	107	15	and	and	CCONJ
mkg-872	107	16	osteoclastic	osteoclastic	ADJ
mkg-872	107	17	bone	bone	NOUN
mkg-872	107	18	resorption	resorption	NOUN
mkg-872	107	19	.	.	PUNCT
mkg-872	108	1	levels	level	NOUN
mkg-872	108	2	of	of	ADP
mkg-872	108	3	il-1β	il-1β	PROPN
mkg-872	108	4	have	have	AUX
mkg-872	108	5	been	be	AUX
mkg-872	108	6	found	find	VERB
mkg-872	108	7	to	to	PART
mkg-872	108	8	be	be	AUX
mkg-872	108	9	consistently	consistently	ADV
mkg-872	108	10	associated	associate	VERB
mkg-872	108	11	with	with	ADP
mkg-872	108	12	the	the	DET
mkg-872	108	13	severity	severity	NOUN
mkg-872	108	14	of	of	ADP
mkg-872	108	15	periodontal	periodontal	ADJ
mkg-872	108	16	disease.23	disease.23	VERB
mkg-872	108	17	the	the	DET
mkg-872	108	18	acute	acute	PROPN
mkg-872	108	19	infl	infl	PROPN
mkg-872	108	20	ammatory	ammatory	NOUN
mkg-872	108	21	response	response	NOUN
mkg-872	108	22	in	in	ADP
mkg-872	108	23	periodontal	periodontal	ADJ
mkg-872	108	24	disease	disease	NOUN
mkg-872	108	25	is	be	AUX
mkg-872	108	26	mmps	mmp	NOUN
mkg-872	108	27	.	.	PUNCT
mkg-872	109	1	it	it	PRON
mkg-872	109	2	released	release	VERB
mkg-872	109	3	by	by	ADP
mkg-872	109	4	inflammatory	inflammatory	ADJ
mkg-872	109	5	cells	cell	NOUN
mkg-872	109	6	,	,	PUNCT
mkg-872	109	7	polymorphonuclear	polymorphonuclear	NOUN
mkg-872	109	8	leukocytes	leukocyte	NOUN
mkg-872	109	9	and	and	CCONJ
mkg-872	109	10	osteoclasts	osteoclast	NOUN
mkg-872	109	11	,	,	PUNCT
mkg-872	109	12	leading	lead	VERB
mkg-872	109	13	to	to	ADP
mkg-872	109	14	the	the	DET
mkg-872	109	15	degradation	degradation	NOUN
mkg-872	109	16	of	of	ADP
mkg-872	109	17	connective	connective	ADJ
mkg-872	109	18	tissue	tissue	NOUN
mkg-872	109	19	collagen	collagen	NOUN
mkg-872	109	20	and	and	CCONJ
mkg-872	109	21	alveolar	alveolar	ADJ
mkg-872	109	22	bone	bone	NOUN
mkg-872	109	23	that	that	PRON
mkg-872	109	24	have	have	AUX
mkg-872	109	25	also	also	ADV
mkg-872	109	26	been	be	AUX
mkg-872	109	27	shown	show	VERB
mkg-872	109	28	to	to	PART
mkg-872	109	29	aid	aid	VERB
mkg-872	109	30	in	in	ADP
mkg-872	109	31	the	the	DET
mkg-872	109	32	diagnosis	diagnosis	NOUN
mkg-872	109	33	of	of	ADP
mkg-872	109	34	periodontal	periodontal	ADJ
mkg-872	109	35	disease	disease	NOUN
mkg-872	109	36	.	.	PUNCT
mkg-872	110	1	the	the	DET
mkg-872	110	2	mmp-8	mmp-8	ADJ
mkg-872	110	3	in	in	ADP
mkg-872	110	4	gcf	gcf	PROPN
mkg-872	110	5	is	be	AUX
mkg-872	110	6	very	very	ADV
mkg-872	110	7	effective	effective	ADJ
mkg-872	110	8	in	in	ADP
mkg-872	110	9	evaluating	evaluate	VERB
mkg-872	110	10	the	the	DET
mkg-872	110	11	outcome	outcome	NOUN
mkg-872	110	12	of	of	ADP
mkg-872	110	13	periodontal	periodontal	ADJ
mkg-872	110	14	treatment	treatment	NOUN
mkg-872	110	15	.	.	PUNCT
mkg-872	111	1	salivary	salivary	ADJ
mkg-872	111	2	levels	level	NOUN
mkg-872	111	3	of	of	ADP
mkg-872	111	4	il-1β	il-1β	PROPN
mkg-872	111	5	,	,	PUNCT
mkg-872	111	6	mmp-8	mmp-8	ADV
mkg-872	111	7	,	,	PUNCT
mkg-872	111	8	opg	opg	NOUN
mkg-872	111	9	,	,	PUNCT
mkg-872	111	10	and	and	CCONJ
mkg-872	111	11	mip-1α	mip-1α	PROPN
mkg-872	111	12	refl	refl	PROPN
mkg-872	111	13	ected	ected	ADJ
mkg-872	111	14	disease	disease	NOUN
mkg-872	111	15	severity	severity	NOUN
mkg-872	111	16	and	and	CCONJ
mkg-872	111	17	response	response	NOUN
mkg-872	111	18	to	to	ADP
mkg-872	111	19	therapy	therapy	NOUN
mkg-872	111	20	suggesting	suggest	VERB
mkg-872	111	21	their	their	PRON
mkg-872	111	22	potential	potential	ADJ
mkg-872	111	23	utility	utility	NOUN
mkg-872	111	24	for	for	ADP
mkg-872	111	25	monitoring	monitor	VERB
mkg-872	111	26	periodontal	periodontal	ADJ
mkg-872	111	27	disease	disease	NOUN
mkg-872	111	28	status.13–17	status.13–17	PROPN
mkg-872	111	29	opg	opg	NOUN
mkg-872	111	30	used	use	VERB
mkg-872	111	31	as	as	ADP
mkg-872	111	32	a	a	DET
mkg-872	111	33	marker	marker	NOUN
mkg-872	111	34	of	of	ADP
mkg-872	111	35	bone	bone	NOUN
mkg-872	111	36	turnover.3–5,17	turnover.3–5,17	NOUN
mkg-872	111	37	it	it	PRON
mkg-872	111	38	can	can	AUX
mkg-872	111	39	be	be	AUX
mkg-872	111	40	concluded	conclude	VERB
mkg-872	111	41	that	that	SCONJ
mkg-872	111	42	the	the	DET
mkg-872	111	43	indicators	indicator	NOUN
mkg-872	111	44	of	of	ADP
mkg-872	111	45	acute	acute	NOUN
mkg-872	111	46	periodontitis	periodontitis	NOUN
mkg-872	111	47	can	can	AUX
mkg-872	111	48	detect	detect	VERB
mkg-872	111	49	with	with	ADP
mkg-872	111	50	β	β	NOUN
mkg-872	111	51	-	-	ADJ
mkg-872	111	52	glucuronidase	glucuronidase	NOUN
mkg-872	111	53	and	and	CCONJ
mkg-872	111	54	ast	ast	NOUN
mkg-872	111	55	,	,	PUNCT
mkg-872	111	56	il-1β	il-1β	PROPN
mkg-872	111	57	,	,	PUNCT
mkg-872	111	58	and	and	CCONJ
mkg-872	111	59	mmp-8	mmp-8	ADV
mkg-872	111	60	,	,	PUNCT
mkg-872	111	61	whereas	whereas	SCONJ
mkg-872	111	62	indicators	indicator	NOUN
mkg-872	111	63	for	for	ADP
mkg-872	111	64	chronic	chronic	ADJ
mkg-872	111	65	periodontitis	periodontitis	NOUN
mkg-872	111	66	can	can	AUX
mkg-872	111	67	detect	detect	VERB
mkg-872	111	68	with	with	ADP
mkg-872	111	69	alp	alp	PROPN
mkg-872	111	70	.	.	PUNCT
mkg-872	112	1	the	the	DET
mkg-872	112	2	indicators	indicator	NOUN
mkg-872	112	3	for	for	ADP
mkg-872	112	4	collagen	collagen	NOUN
mkg-872	112	5	degradation	degradation	NOUN
mkg-872	112	6	and	and	CCONJ
mkg-872	112	7	bone	bone	NOUN
mkg-872	112	8	turnover	turnover	NOUN
mkg-872	112	9	suggest	suggest	VERB
mkg-872	112	10	ictp	ictp	ADJ
mkg-872	112	11	,	,	PUNCT
mkg-872	112	12	fibronectin	fibronectin	NOUN
mkg-872	112	13	fragments	fragment	NOUN
mkg-872	112	14	,	,	PUNCT
mkg-872	112	15	and	and	CCONJ
mkg-872	112	16	osteonectin	osteonectin	X
mkg-872	112	17	.	.	PUNCT
mkg-872	113	1	the	the	DET
mkg-872	113	2	indicators	indicator	NOUN
mkg-872	113	3	of	of	ADP
mkg-872	113	4	severity	severity	NOUN
mkg-872	113	5	of	of	ADP
mkg-872	113	6	periodontitis	periodontitis	NOUN
mkg-872	113	7	especially	especially	ADV
mkg-872	113	8	can	can	AUX
mkg-872	113	9	be	be	AUX
mkg-872	113	10	predict	predict	VERB
mkg-872	113	11	by	by	ADP
mkg-872	113	12	b.	b.	PROPN
mkg-872	113	13	forsythus	forsythus	PROPN
mkg-872	113	14	.	.	PUNCT
mkg-872	114	1	references	reference	NOUN
mkg-872	114	2	1	1	NUM
mkg-872	114	3	.	.	PUNCT
mkg-872	114	4	keles	keles	PROPN
mkg-872	114	5	gc	gc	PROPN
mkg-872	114	6	,	,	PUNCT
mkg-872	114	7	acikgoz	acikgoz	ADJ
mkg-872	114	8	g	g	PROPN
mkg-872	114	9	,	,	PUNCT
mkg-872	114	10	ayas	ayas	PROPN
mkg-872	114	11	b	b	NOUN
mkg-872	114	12	,	,	PUNCT
mkg-872	114	13	sakallioglu	sakallioglu	NOUN
mkg-872	114	14	e	e	PROPN
mkg-872	114	15	,	,	PUNCT
mkg-872	114	16	firatli	firatli	PROPN
mkg-872	114	17	e.	e.	PROPN
mkg-872	114	18	determination	determination	NOUN
mkg-872	114	19	of	of	ADP
mkg-872	114	20	systemically	systemically	ADV
mkg-872	114	21	and	and	CCONJ
mkg-872	114	22	locally	locally	ADV
mkg-872	114	23	induce	induce	VERB
mkg-872	114	24	periodontal	periodontal	ADJ
mkg-872	114	25	defect	defect	NOUN
mkg-872	114	26	in	in	ADP
mkg-872	114	27	rats	rat	NOUN
mkg-872	114	28	.	.	PUNCT
mkg-872	115	1	indiana	indiana	PROPN
mkg-872	115	2	j	j	PROPN
mkg-872	115	3	med	med	PROPN
mkg-872	115	4	res	re	NOUN
mkg-872	115	5	2005	2005	NUM
mkg-872	115	6	;	;	PUNCT
mkg-872	115	7	121	121	NUM
mkg-872	115	8	:	:	PUNCT
mkg-872	115	9	176–84	176–84	NOUN
mkg-872	115	10	.	.	PUNCT
mkg-872	116	1	2	2	X
mkg-872	116	2	.	.	X
mkg-872	116	3	khiste	khiste	PROPN
mkg-872	116	4	sv	sv	PROPN
mkg-872	116	5	,	,	PUNCT
mkg-872	116	6	ranganath	ranganath	NOUN
mkg-872	116	7	v	v	NOUN
mkg-872	116	8	,	,	PUNCT
mkg-872	116	9	nichani	nichani	ADJ
mkg-872	116	10	as	as	ADP
mkg-872	116	11	,	,	PUNCT
mkg-872	116	12	rajani	rajani	PROPN
mkg-872	116	13	v.	v.	ADP
mkg-872	116	14	critical	critical	ADJ
mkg-872	116	15	analysis	analysis	NOUN
mkg-872	116	16	of	of	ADP
mkg-872	116	17	biomarkers	biomarker	NOUN
mkg-872	116	18	in	in	ADP
mkg-872	116	19	the	the	DET
mkg-872	116	20	current	current	ADJ
mkg-872	116	21	periodontal	periodontal	ADJ
mkg-872	116	22	practice	practice	NOUN
mkg-872	116	23	.	.	PUNCT
mkg-872	117	1	j	j	PROPN
mkg-872	117	2	indian	indian	ADJ
mkg-872	117	3	soc	soc	PROPN
mkg-872	117	4	periodontol	periodontol	PROPN
mkg-872	117	5	2011	2011	NUM
mkg-872	117	6	;	;	PUNCT
mkg-872	117	7	15	15	NUM
mkg-872	117	8	:	:	PUNCT
mkg-872	117	9	104–10	104–10	NUM
mkg-872	117	10	.	.	NOUN
mkg-872	118	1	3	3	X
mkg-872	118	2	.	.	X
mkg-872	118	3	taba	taba	PROPN
mkg-872	118	4	m	m	PROPN
mkg-872	118	5	,	,	PUNCT
mkg-872	118	6	kinney	kinney	PROPN
mkg-872	118	7	j	j	PROPN
mkg-872	118	8	,	,	PUNCT
mkg-872	118	9	kim	kim	PROPN
mkg-872	118	10	as	as	ADP
mkg-872	118	11	,	,	PUNCT
mkg-872	118	12	giannobile	giannobile	ADJ
mkg-872	118	13	v.	v.	ADP
mkg-872	118	14	diagnostic	diagnostic	ADJ
mkg-872	118	15	biomarkers	biomarker	NOUN
mkg-872	118	16	for	for	ADP
mkg-872	118	17	oral	oral	ADJ
mkg-872	118	18	and	and	CCONJ
mkg-872	118	19	periodontal	periodontal	ADJ
mkg-872	118	20	diseases	disease	NOUN
mkg-872	118	21	.	.	PUNCT
mkg-872	119	1	dent	dent	PROPN
mkg-872	119	2	clin	clin	PROPN
mkg-872	119	3	north	north	PROPN
mkg-872	119	4	am	be	AUX
mkg-872	119	5	2005	2005	NUM
mkg-872	119	6	;	;	PUNCT
mkg-872	119	7	49(3	49(3	NUM
mkg-872	119	8	):	):	PUNCT
mkg-872	119	9	551–6	551–6	NUM
mkg-872	119	10	.	.	NOUN
mkg-872	119	11	4	4	NUM
mkg-872	119	12	.	.	X
mkg-872	119	13	ali	ali	PROPN
mkg-872	119	14	j	j	PROPN
mkg-872	119	15	,	,	PUNCT
mkg-872	119	16	pramod	pramod	PROPN
mkg-872	119	17	k	k	PROPN
mkg-872	119	18	,	,	PUNCT
mkg-872	119	19	tahir	tahir	PROPN
mkg-872	119	20	ma	ma	PROPN
mkg-872	119	21	,	,	PUNCT
mkg-872	119	22	ansari	ansari	PROPN
mkg-872	119	23	sh	sh	PROPN
mkg-872	119	24	,	,	PUNCT
mkg-872	119	25	autoimmune	autoimmune	ADJ
mkg-872	119	26	responses	response	NOUN
mkg-872	119	27	in	in	ADP
mkg-872	119	28	periodontal	periodontal	ADJ
mkg-872	119	29	disease	disease	NOUN
mkg-872	119	30	.	.	PUNCT
mkg-872	120	1	autoimmunity	autoimmunity	NOUN
mkg-872	120	2	reviews	review	NOUN
mkg-872	120	3	2011	2011	NUM
mkg-872	120	4	may	may	AUX
mkg-872	120	5	;	;	PUNCT
mkg-872	120	6	10	10	NUM
mkg-872	120	7	(	(	PUNCT
mkg-872	120	8	issue	issue	NOUN
mkg-872	120	9	7	7	NUM
mkg-872	120	10	):	):	PUNCT
mkg-872	120	11	426–31	426–31	NOUN
mkg-872	120	12	.	.	PUNCT
mkg-872	121	1	5	5	NUM
mkg-872	121	2	.	.	X
mkg-872	121	3	miller	miller	PROPN
mkg-872	121	4	cs	cs	PROPN
mkg-872	121	5	,	,	PUNCT
mkg-872	121	6	king	king	PROPN
mkg-872	121	7	cp	cp	PROPN
mkg-872	121	8	,	,	PUNCT
mkg-872	121	9	langub	langub	PROPN
mkg-872	121	10	mc	mc	PROPN
mkg-872	121	11	,	,	PUNCT
mkg-872	121	12	kryscio	kryscio	PROPN
mkg-872	121	13	rj	rj	PROPN
mkg-872	121	14	,	,	PUNCT
mkg-872	121	15	thomas	thomas	PROPN
mkg-872	121	16	mv	mv	PROPN
mkg-872	121	17	.	.	PROPN
mkg-872	122	1	salivary	salivary	ADJ
mkg-872	122	2	biomarkers	biomarker	NOUN
mkg-872	122	3	of	of	ADP
mkg-872	122	4	existing	exist	VERB
mkg-872	122	5	periodontal	periodontal	ADJ
mkg-872	122	6	disease	disease	NOUN
mkg-872	122	7	:	:	PUNCT
mkg-872	122	8	a	a	DET
mkg-872	122	9	cross	cross	ADJ
mkg-872	122	10	-	-	ADJ
mkg-872	122	11	sectional	sectional	ADJ
mkg-872	122	12	study	study	NOUN
mkg-872	122	13	.	.	PUNCT
mkg-872	123	1	j	j	PROPN
mkg-872	123	2	am	be	AUX
mkg-872	123	3	dent	dent	ADJ
mkg-872	123	4	assoc	assoc	PROPN
mkg-872	123	5	2006	2006	NUM
mkg-872	123	6	;	;	PUNCT
mkg-872	123	7	137	137	NUM
mkg-872	123	8	:	:	PUNCT
mkg-872	123	9	322–9	322–9	NUM
mkg-872	123	10	.	.	PUNCT
mkg-872	124	1	81hamzah	81hamzah	NUM
mkg-872	124	2	:	:	PUNCT
mkg-872	124	3	saliva	saliva	NOUN
mkg-872	124	4	as	as	ADP
mkg-872	124	5	a	a	DET
mkg-872	124	6	future	future	ADJ
mkg-872	124	7	potential	potential	ADJ
mkg-872	124	8	predictor	predictor	NOUN
mkg-872	124	9	6	6	NUM
mkg-872	124	10	.	.	PUNCT
mkg-872	124	11	grbic	grbic	PROPN
mkg-872	124	12	jt	jt	PROPN
mkg-872	124	13	,	,	PUNCT
mkg-872	124	14	steven	steven	PROPN
mkg-872	124	15	p	p	PROPN
mkg-872	124	16	,	,	PUNCT
mkg-872	124	17	engebretson	engebretson	NOUN
mkg-872	124	18	sp	sp	NOUN
mkg-872	124	19	.	.	PUNCT
mkg-872	125	1	the	the	DET
mkg-872	125	2	future	future	NOUN
mkg-872	125	3	of	of	ADP
mkg-872	125	4	periodontal	periodontal	ADJ
mkg-872	125	5	diagnostic	diagnostic	ADJ
mkg-872	125	6	testing	testing	NOUN
mkg-872	125	7	.	.	PUNCT
mkg-872	126	1	dentistry	dentistry	NOUN
mkg-872	126	2	today	today	NOUN
mkg-872	126	3	.	.	PUNCT
mkg-872	127	1	2010	2010	NUM
mkg-872	127	2	.	.	PUNCT
mkg-872	128	1	available	available	ADJ
mkg-872	128	2	at	at	ADP
mkg-872	128	3	:	:	PUNCT
mkg-872	128	4	http://www	http://www	PROPN
mkg-872	128	5	.	.	PROPN
mkg-872	128	6	dentistrytoday.com/periodontics/1617	dentistrytoday.com/periodontics/1617	PROPN
mkg-872	128	7	.	.	PUNCT
mkg-872	129	1	accessed	access	VERB
mkg-872	129	2	october	october	PROPN
mkg-872	129	3	30th	30th	NOUN
mkg-872	129	4	,	,	PUNCT
mkg-872	129	5	2010	2010	NUM
mkg-872	129	6	.	.	PUNCT
mkg-872	130	1	7	7	X
mkg-872	130	2	.	.	X
mkg-872	130	3	giannobile	giannobile	PROPN
mkg-872	130	4	wv	wv	PROPN
mkg-872	130	5	,	,	PUNCT
mkg-872	130	6	beikler	beikler	PROPN
mkg-872	130	7	t	t	PROPN
mkg-872	130	8	,	,	PUNCT
mkg-872	130	9	kinney	kinney	PROPN
mkg-872	130	10	js	js	PROPN
mkg-872	130	11	,	,	PUNCT
mkg-872	130	12	ramseier	ramseier	PROPN
mkg-872	130	13	ca	ca	PROPN
mkg-872	130	14	,	,	PUNCT
mkg-872	130	15	morelli	morelli	PROPN
mkg-872	130	16	t	t	PROPN
mkg-872	130	17	,	,	PUNCT
mkg-872	130	18	wong	wong	PROPN
mkg-872	130	19	dt	dt	PROPN
mkg-872	130	20	.	.	PUNCT
mkg-872	130	21	saliva	saliva	NOUN
mkg-872	130	22	as	as	ADP
mkg-872	130	23	a	a	DET
mkg-872	130	24	diagnostic	diagnostic	ADJ
mkg-872	130	25	tool	tool	NOUN
mkg-872	130	26	for	for	ADP
mkg-872	130	27	periodontal	periodontal	ADJ
mkg-872	130	28	disease	disease	NOUN
mkg-872	130	29	:	:	PUNCT
mkg-872	130	30	current	current	ADJ
mkg-872	130	31	state	state	NOUN
mkg-872	130	32	and	and	CCONJ
mkg-872	130	33	future	future	ADJ
mkg-872	130	34	directions	direction	NOUN
mkg-872	130	35	.	.	PUNCT
mkg-872	131	1	periodontology	periodontology	NOUN
mkg-872	131	2	2000	2000	NUM
mkg-872	131	3	,	,	PUNCT
mkg-872	131	4	2009	2009	NUM
mkg-872	131	5	;	;	PUNCT
mkg-872	131	6	50	50	NUM
mkg-872	131	7	:	:	PUNCT
mkg-872	131	8	52–64	52–64	NUM
mkg-872	131	9	.	.	NOUN
mkg-872	131	10	8	8	NUM
mkg-872	131	11	.	.	X
mkg-872	132	1	pfaffe	pfaffe	PROPN
mkg-872	132	2	t	t	PROPN
mkg-872	132	3	,	,	PUNCT
mkg-872	132	4	cooper	cooper	PROPN
mkg-872	132	5	-	-	PUNCT
mkg-872	132	6	white	white	PROPN
mkg-872	132	7	j	j	PROPN
mkg-872	132	8	,	,	PUNCT
mkg-872	132	9	beyerlein	beyerlein	PROPN
mkg-872	132	10	p	p	PROPN
mkg-872	132	11	,	,	PUNCT
mkg-872	132	12	kostner	kostner	X
mkg-872	132	13	k	k	PROPN
mkg-872	132	14	,	,	PUNCT
mkg-872	132	15	punyadeera	punyadeera	ADJ
mkg-872	132	16	c.	c.	PROPN
mkg-872	132	17	diagnostic	diagnostic	ADJ
mkg-872	132	18	potential	potential	NOUN
mkg-872	132	19	of	of	ADP
mkg-872	132	20	saliva	saliva	NOUN
mkg-872	132	21	:	:	PUNCT
mkg-872	132	22	current	current	ADJ
mkg-872	132	23	state	state	NOUN
mkg-872	132	24	and	and	CCONJ
mkg-872	132	25	future	future	ADJ
mkg-872	132	26	applications	application	NOUN
mkg-872	132	27	.	.	PUNCT
mkg-872	133	1	clinical	clinical	ADJ
mkg-872	133	2	chemistry	chemistry	NOUN
mkg-872	133	3	2011	2011	NUM
mkg-872	133	4	;	;	PUNCT
mkg-872	133	5	57	57	NUM
mkg-872	133	6	:	:	PUNCT
mkg-872	133	7	675–87	675–87	NOUN
mkg-872	133	8	.	.	PUNCT
mkg-872	134	1	9	9	X
mkg-872	134	2	.	.	X
mkg-872	134	3	reddy	reddy	PROPN
mkg-872	134	4	s	s	PROPN
mkg-872	134	5	,	,	PUNCT
mkg-872	134	6	kaul	kaul	PROPN
mkg-872	134	7	s	s	PROPN
mkg-872	134	8	,	,	PUNCT
mkg-872	134	9	prasad	prasad	PROPN
mkg-872	134	10	mgs	mgs	NOUN
mkg-872	134	11	,	,	PUNCT
mkg-872	134	12	agnihotri	agnihotri	PROPN
mkg-872	134	13	j	j	PROPN
mkg-872	134	14	,	,	PUNCT
mkg-872	134	15	asutkar	asutkar	PROPN
mkg-872	134	16	h	h	PROPN
mkg-872	134	17	,	,	PUNCT
mkg-872	134	18	bhowmik	bhowmik	ADJ
mkg-872	134	19	n.	n.	NOUN
mkg-872	134	20	biomarkers	biomarker	NOUN
mkg-872	134	21	in	in	ADP
mkg-872	134	22	periodontal	periodontal	ADJ
mkg-872	134	23	diagnosis	diagnosis	NOUN
mkg-872	134	24	:	:	PUNCT
mkg-872	134	25	“	"	PUNCT
mkg-872	134	26	what	what	PRON
mkg-872	134	27	the	the	DET
mkg-872	134	28	future	future	NOUN
mkg-872	134	29	holds	hold	VERB
mkg-872	134	30	...	...	PUNCT
mkg-872	134	31	”	"	PUNCT
mkg-872	134	32	.	.	PUNCT
mkg-872	135	1	int	int	PROPN
mkg-872	135	2	j	j	PROPN
mkg-872	135	3	of	of	ADP
mkg-872	135	4	clin	clin	PROPN
mkg-872	135	5	dent	dent	PROPN
mkg-872	135	6	sci	sci	PROPN
mkg-872	135	7	2011	2011	NUM
mkg-872	135	8	;	;	PUNCT
mkg-872	135	9	2(1	2(1	NUM
mkg-872	135	10	):	):	PUNCT
mkg-872	135	11	76–83	76–83	NUM
mkg-872	135	12	.	.	NOUN
mkg-872	135	13	10	10	NUM
mkg-872	135	14	.	.	PUNCT
mkg-872	136	1	ansai	ansai	PROPN
mkg-872	136	2	t	t	PROPN
mkg-872	136	3	,	,	PUNCT
mkg-872	136	4	soh	soh	PROPN
mkg-872	137	1	i	i	PROPN
mkg-872	137	2	,	,	PUNCT
mkg-872	137	3	ishisaka	ishisaka	ADV
mkg-872	137	4	a	a	PRON
mkg-872	137	5	,	,	PUNCT
mkg-872	137	6	yoshida	yoshida	PROPN
mkg-872	137	7	a	a	PROPN
mkg-872	137	8	,	,	PUNCT
mkg-872	137	9	awano	awano	PROPN
mkg-872	137	10	s	s	PART
mkg-872	137	11	,	,	PUNCT
mkg-872	137	12	hamasaki	hamasaki	PROPN
mkg-872	137	13	t	t	PROPN
mkg-872	137	14	,	,	PUNCT
mkg-872	137	15	sonoki	sonoki	PROPN
mkg-872	137	16	k	k	PROPN
mkg-872	137	17	,	,	PUNCT
mkg-872	137	18	takata	takata	NOUN
mkg-872	137	19	y	y	PROPN
mkg-872	137	20	,	,	PUNCT
mkg-872	137	21	takehara	takehara	PROPN
mkg-872	137	22	t.	t.	ADJ
mkg-872	137	23	determination	determination	NOUN
mkg-872	137	24	of	of	ADP
mkg-872	137	25	cortisol	cortisol	NOUN
mkg-872	137	26	and	and	CCONJ
mkg-872	137	27	dehydroepiandrosterone	dehydroepiandrosterone	NOUN
mkg-872	137	28	levels	level	NOUN
mkg-872	137	29	in	in	ADP
mkg-872	137	30	saliva	saliva	NOUN
mkg-872	137	31	for	for	ADP
mkg-872	137	32	screening	screening	NOUN
mkg-872	137	33	of	of	ADP
mkg-872	137	34	periodontitis	periodontitis	NOUN
mkg-872	137	35	in	in	ADP
mkg-872	137	36	older	old	ADJ
mkg-872	137	37	japanese	japanese	ADJ
mkg-872	137	38	adults	adult	NOUN
mkg-872	137	39	.	.	PUNCT
mkg-872	138	1	int	int	NOUN
mkg-872	138	2	j	j	PROPN
mkg-872	138	3	dent	dent	PROPN
mkg-872	138	4	2009	2009	NUM
mkg-872	138	5	;	;	PUNCT
mkg-872	138	6	2009	2009	NUM
mkg-872	138	7	:	:	PUNCT
mkg-872	138	8	280737	280737	NUM
mkg-872	138	9	.	.	PUNCT
mkg-872	139	1	11	11	NUM
mkg-872	139	2	.	.	X
mkg-872	140	1	kinney	kinney	PROPN
mkg-872	140	2	js	js	PROPN
mkg-872	140	3	.	.	PROPN
mkg-872	140	4	,	,	PUNCT
mkg-872	140	5	ramseier	ramseier	PROPN
mkg-872	140	6	ca	ca	PROPN
mkg-872	140	7	,	,	PUNCT
mkg-872	140	8	giannobile	giannobile	PROPN
mkg-872	140	9	wv	wv	PROPN
mkg-872	140	10	.	.	PUNCT
mkg-872	141	1	oral	oral	ADJ
mkg-872	141	2	fluid	fluid	NOUN
mkg-872	141	3	–	–	PUNCT
mkg-872	141	4	based	base	VERB
mkg-872	141	5	biomarkers	biomarker	NOUN
mkg-872	141	6	of	of	ADP
mkg-872	141	7	alveolar	alveolar	ADJ
mkg-872	141	8	bone	bone	NOUN
mkg-872	141	9	loss	loss	NOUN
mkg-872	141	10	in	in	ADP
mkg-872	141	11	periodontitis	periodontitis	NOUN
mkg-872	141	12	.	.	PUNCT
mkg-872	142	1	ann	ann	PROPN
mkg-872	142	2	ny	ny	PROPN
mkg-872	142	3	acad	acad	PROPN
mkg-872	142	4	sci	sci	PROPN
mkg-872	142	5	2007	2007	NUM
mkg-872	142	6	;	;	PUNCT
mkg-872	142	7	1098	1098	NUM
mkg-872	142	8	:	:	PUNCT
mkg-872	142	9	230–51	230–51	NUM
mkg-872	142	10	.	.	X
mkg-872	142	11	12	12	NUM
mkg-872	142	12	.	.	PUNCT
mkg-872	143	1	desai	desai	PROPN
mkg-872	143	2	s	s	PROPN
mkg-872	143	3	,	,	PUNCT
mkg-872	143	4	shinde	shinde	PROPN
mkg-872	143	5	h	h	PROPN
mkg-872	143	6	,	,	PUNCT
mkg-872	143	7	mudda	mudda	PROPN
mkg-872	143	8	j	j	PROPN
mkg-872	143	9	,	,	PUNCT
mkg-872	143	10	patil	patil	PROPN
mkg-872	143	11	v.	v.	PROPN
mkg-872	143	12	levels	level	NOUN
mkg-872	143	13	of	of	ADP
mkg-872	143	14	alkaline	alkaline	ADJ
mkg-872	143	15	phosphatase	phosphatase	NOUN
mkg-872	143	16	(	(	PUNCT
mkg-872	143	17	alp	alp	PROPN
mkg-872	143	18	)	)	PUNCT
mkg-872	143	19	in	in	ADP
mkg-872	143	20	saliva	saliva	NOUN
mkg-872	143	21	of	of	ADP
mkg-872	143	22	patients	patient	NOUN
mkg-872	143	23	with	with	ADP
mkg-872	143	24	chronic	chronic	ADJ
mkg-872	143	25	periodontitis	periodontitis	NOUN
mkg-872	143	26	;	;	PUNCT
mkg-872	143	27	a	a	DET
mkg-872	143	28	clinical	clinical	ADJ
mkg-872	143	29	and	and	CCONJ
mkg-872	143	30	biochemical	biochemical	ADJ
mkg-872	143	31	study	study	NOUN
mkg-872	143	32	.	.	PUNCT
mkg-872	144	1	the	the	DET
mkg-872	144	2	internet	internet	NOUN
mkg-872	144	3	j	j	PROPN
mkg-872	144	4	dental	dental	ADJ
mkg-872	144	5	science	science	NOUN
mkg-872	144	6	2009	2009	NUM
mkg-872	144	7	;	;	PUNCT
mkg-872	144	8	8(1	8(1	NOUN
mkg-872	144	9	):	):	PUNCT
mkg-872	144	10	1–19	1–19	NOUN
mkg-872	144	11	.	.	PUNCT
mkg-872	145	1	13	13	NUM
mkg-872	145	2	.	.	X
mkg-872	145	3	gursoy	gursoy	PROPN
mkg-872	145	4	uk	uk	PROPN
mkg-872	145	5	,	,	PUNCT
mkg-872	145	6	könönen	könönen	PROPN
mkg-872	145	7	e	e	PROPN
mkg-872	145	8	,	,	PUNCT
mkg-872	145	9	uitto	uitto	ADJ
mkg-872	145	10	vj	vj	PROPN
mkg-872	145	11	,	,	PUNCT
mkg-872	145	12	pirkko	pirkko	PROPN
mkg-872	145	13	j	j	PROPN
mkg-872	145	14	,	,	PUNCT
mkg-872	145	15	pussinen	pussinen	PROPN
mkg-872	145	16	pj	pj	PROPN
mkg-872	145	17	,	,	PUNCT
mkg-872	145	18	kati	kati	PROPN
mkg-872	145	19	hyvärinen	hyvärinen	PROPN
mkg-872	145	20	k	k	PROPN
mkg-872	145	21	,	,	PUNCT
mkg-872	145	22	liisa	liisa	VERB
mkg-872	145	23	suominen	suominen	NOUN
mkg-872	145	24	-	-	PUNCT
mkg-872	145	25	taipale	taipale	NOUN
mkg-872	145	26	l	l	NOUN
mkg-872	145	27	,	,	PUNCT
mkg-872	145	28	knuuttila	knuuttila	PROPN
mkg-872	145	29	m.	m.	NOUN
mkg-872	145	30	salivary	salivary	PROPN
mkg-872	145	31	interleukin-1β	interleukin-1β	PROPN
mkg-872	145	32	concentration	concentration	NOUN
mkg-872	145	33	and	and	CCONJ
mkg-872	145	34	the	the	DET
mkg-872	145	35	presence	presence	NOUN
mkg-872	145	36	of	of	ADP
mkg-872	145	37	multiple	multiple	ADJ
mkg-872	145	38	pathogens	pathogen	NOUN
mkg-872	145	39	in	in	ADP
mkg-872	145	40	periodontitis	periodontitis	NOUN
mkg-872	145	41	.	.	PUNCT
mkg-872	146	1	j	j	PROPN
mkg-872	146	2	clin	clin	PROPN
mkg-872	146	3	periodontol	periodontol	PROPN
mkg-872	146	4	2009	2009	NUM
mkg-872	146	5	;	;	PUNCT
mkg-872	146	6	36(11	36(11	NUM
mkg-872	146	7	):	):	PUNCT
mkg-872	146	8	922–7	922–7	NOUN
mkg-872	146	9	.	.	PUNCT
mkg-872	146	10	14	14	NUM
mkg-872	147	1	.	.	X
mkg-872	147	2	aurer	aurer	AUX
mkg-872	148	1	a	a	PRON
mkg-872	148	2	,	,	PUNCT
mkg-872	148	3	jorgic	jorgic	NOUN
mkg-872	148	4	-	-	PUNCT
mkg-872	148	5	srdjak	srdjak	NOUN
mkg-872	149	1	k	k	PROPN
mkg-872	149	2	,	,	PUNCT
mkg-872	149	3	plancak	plancak	ADJ
mkg-872	149	4	d	d	PROPN
mkg-872	149	5	,	,	PUNCT
mkg-872	149	6	stavljenic	stavljenic	NOUN
mkg-872	149	7	-	-	PUNCT
mkg-872	149	8	rukavina	rukavina	PROPN
mkg-872	149	9	a	a	PRON
mkg-872	149	10	,	,	PUNCT
mkg-872	149	11	aurerkozelj	aurerkozelj	PROPN
mkg-872	149	12	j.	j.	PROPN
mkg-872	149	13	proinflammatory	proinflammatory	ADJ
mkg-872	149	14	factors	factor	NOUN
mkg-872	149	15	in	in	ADP
mkg-872	149	16	saliva	saliva	NOUN
mkg-872	149	17	as	as	ADP
mkg-872	149	18	possible	possible	ADJ
mkg-872	149	19	markers	marker	NOUN
mkg-872	149	20	for	for	ADP
mkg-872	149	21	periodontal	periodontal	ADJ
mkg-872	149	22	disease	disease	NOUN
mkg-872	149	23	.	.	PUNCT
mkg-872	150	1	coll	coll	PROPN
mkg-872	150	2	antropol	antropol	PROPN
mkg-872	150	3	2005	2005	NUM
mkg-872	150	4	;	;	PUNCT
mkg-872	150	5	29(2	29(2	NUM
mkg-872	150	6	):	):	PUNCT
mkg-872	150	7	435–9	435–9	NOUN
mkg-872	150	8	.	.	NOUN
mkg-872	150	9	15	15	NUM
mkg-872	150	10	.	.	PUNCT
mkg-872	150	11	pradeep	pradeep	PROPN
mkg-872	150	12	ar	ar	PROPN
mkg-872	150	13	,	,	PUNCT
mkg-872	150	14	manojkumar	manojkumar	PROPN
mkg-872	150	15	st	st	PROPN
mkg-872	150	16	,	,	PUNCT
mkg-872	150	17	garima	garima	PROPN
mkg-872	150	18	g	g	PROPN
mkg-872	150	19	,	,	PUNCT
mkg-872	150	20	raju	raju	PROPN
mkg-872	150	21	a.	a.	PROPN
mkg-872	150	22	serum	serum	PROPN
mkg-872	150	23	levels	level	NOUN
mkg-872	150	24	of	of	ADP
mkg-872	150	25	oncostatin	oncostatin	NOUN
mkg-872	150	26	m	m	NOUN
mkg-872	150	27	(	(	PUNCT
mkg-872	150	28	a	a	DET
mkg-872	150	29	gp	gp	NOUN
mkg-872	150	30	130	130	NUM
mkg-872	150	31	cytokine	cytokine	NOUN
mkg-872	150	32	):	):	PUNCT
mkg-872	150	33	an	an	DET
mkg-872	150	34	inflammatory	inflammatory	ADJ
mkg-872	150	35	biomarker	biomarker	NOUN
mkg-872	150	36	in	in	ADP
mkg-872	150	37	periodontal	periodontal	ADJ
mkg-872	150	38	disease	disease	NOUN
mkg-872	150	39	.	.	PUNCT
mkg-872	151	1	biomarkers	biomarker	NOUN
mkg-872	151	2	2010	2010	NUM
mkg-872	151	3	;	;	PUNCT
mkg-872	151	4	15(3	15(3	NUM
mkg-872	151	5	):	):	PUNCT
mkg-872	151	6	277–82	277–82	NUM
mkg-872	151	7	.	.	PROPN
mkg-872	151	8	16	16	NUM
mkg-872	151	9	.	.	PUNCT
mkg-872	152	1	sexton	sexton	PROPN
mkg-872	152	2	wm	wm	PROPN
mkg-872	152	3	,	,	PUNCT
mkg-872	152	4	lin	lin	PROPN
mkg-872	152	5	y	y	PROPN
mkg-872	152	6	,	,	PUNCT
mkg-872	152	7	kryscio	kryscio	PROPN
mkg-872	152	8	rj	rj	PROPN
mkg-872	152	9	,	,	PUNCT
mkg-872	152	10	dawson	dawson	PROPN
mkg-872	152	11	dr	dr	PROPN
mkg-872	152	12	,	,	PUNCT
mkg-872	152	13	ebersole	ebersole	PROPN
mkg-872	152	14	jl	jl	PROPN
mkg-872	152	15	,	,	PUNCT
mkg-872	152	16	miller	miller	PROPN
mkg-872	152	17	cs	cs	PROPN
mkg-872	152	18	.	.	PROPN
mkg-872	152	19	salivary	salivary	ADJ
mkg-872	152	20	biomarkers	biomarker	NOUN
mkg-872	152	21	of	of	ADP
mkg-872	152	22	periodontal	periodontal	ADJ
mkg-872	152	23	disease	disease	NOUN
mkg-872	152	24	in	in	ADP
mkg-872	152	25	response	response	NOUN
mkg-872	152	26	to	to	ADP
mkg-872	152	27	treatment	treatment	NOUN
mkg-872	152	28	.	.	PUNCT
mkg-872	153	1	j	j	PROPN
mkg-872	153	2	clin	clin	PROPN
mkg-872	153	3	periodontol	periodontol	PROPN
mkg-872	153	4	2011	2011	NUM
mkg-872	153	5	may	may	AUX
mkg-872	153	6	;	;	PUNCT
mkg-872	153	7	38(5	38(5	NUM
mkg-872	153	8	):	):	PUNCT
mkg-872	153	9	434–41	434–41	NUM
mkg-872	153	10	.	.	PUNCT
mkg-872	153	11	17	17	NUM
mkg-872	153	12	.	.	PUNCT
mkg-872	154	1	rai	rai	PROPN
mkg-872	154	2	b	b	PROPN
mkg-872	154	3	,	,	PUNCT
mkg-872	154	4	kharb	kharb	PROPN
mkg-872	154	5	s	s	PROPN
mkg-872	154	6	,	,	PUNCT
mkg-872	154	7	jain	jain	PROPN
mkg-872	154	8	r	r	PROPN
mkg-872	154	9	,	,	PUNCT
mkg-872	154	10	anand	anand	PROPN
mkg-872	154	11	sc	sc	PROPN
mkg-872	154	12	.	.	PUNCT
mkg-872	154	13	biomarkers	biomarker	NOUN
mkg-872	154	14	of	of	ADP
mkg-872	154	15	periodontal	periodontal	ADJ
mkg-872	154	16	disease	disease	NOUN
mkg-872	154	17	in	in	ADP
mkg-872	154	18	oral	oral	ADJ
mkg-872	154	19	fluids	fluid	NOUN
mkg-872	154	20	.	.	PUNCT
mkg-872	155	1	j	j	PROPN
mkg-872	155	2	oral	oral	ADJ
mkg-872	155	3	sci	sci	PROPN
mkg-872	155	4	2008	2008	NUM
mkg-872	155	5	;	;	PUNCT
mkg-872	155	6	50	50	NUM
mkg-872	155	7	:	:	PUNCT
mkg-872	155	8	53–6	53–6	NUM
mkg-872	155	9	.	.	PUNCT
mkg-872	155	10	18	18	NUM
mkg-872	155	11	.	.	X
mkg-872	155	12	totan	totan	PROPN
mkg-872	155	13	a	a	DET
mkg-872	155	14	,	,	PUNCT
mkg-872	155	15	greabu	greabu	NOUN
mkg-872	155	16	m	m	PROPN
mkg-872	155	17	,	,	PUNCT
mkg-872	155	18	totan	totan	PROPN
mkg-872	155	19	c	c	NOUN
mkg-872	155	20	,	,	PUNCT
mkg-872	155	21	spinu	spinu	NOUN
mkg-872	155	22	t.	t.	PROPN
mkg-872	155	23	salivary	salivary	ADJ
mkg-872	155	24	aspartate	aspartate	NOUN
mkg-872	155	25	aminotransferase	aminotransferase	NOUN
mkg-872	155	26	,	,	PUNCT
mkg-872	155	27	alanine	alanine	NOUN
mkg-872	155	28	aminotransferase	aminotransferase	NOUN
mkg-872	155	29	and	and	CCONJ
mkg-872	155	30	alkaline	alkaline	NOUN
mkg-872	155	31	phosphatase	phosphatase	NOUN
mkg-872	155	32	:	:	PUNCT
mkg-872	155	33	possible	possible	ADJ
mkg-872	155	34	markers	marker	NOUN
mkg-872	155	35	in	in	ADP
mkg-872	155	36	periodontal	periodontal	ADJ
mkg-872	155	37	diseases	disease	NOUN
mkg-872	155	38	?	?	PUNCT
mkg-872	156	1	clin	clin	PROPN
mkg-872	156	2	chemistry	chemistry	PROPN
mkg-872	156	3	and	and	CCONJ
mkg-872	156	4	laboratory	laboratory	NOUN
mkg-872	156	5	med	me	VERB
mkg-872	156	6	2006	2006	NUM
mkg-872	156	7	;	;	PUNCT
mkg-872	157	1	44(5	44(5	NUM
mkg-872	157	2	):	):	PUNCT
mkg-872	157	3	612–5	612–5	NOUN
mkg-872	157	4	.	.	NOUN
mkg-872	157	5	19	19	NUM
mkg-872	157	6	.	.	PUNCT
mkg-872	157	7	todorovic	todorovic	PROPN
mkg-872	157	8	t	t	PROPN
mkg-872	157	9	,	,	PUNCT
mkg-872	157	10	dozic	dozic	PROPN
mkg-872	158	1	i	i	PROPN
mkg-872	158	2	,	,	PUNCT
mkg-872	158	3	vicente	vicente	PROPN
mkg-872	158	4	-	-	PUNCT
mkg-872	158	5	barrero	barrero	NOUN
mkg-872	158	6	m	m	PROPN
mkg-872	158	7	,	,	PUNCT
mkg-872	158	8	ljuskovic	ljuskovic	PROPN
mkg-872	158	9	b	b	PROPN
mkg-872	158	10	,	,	PUNCT
mkg-872	158	11	pejovic	pejovic	PROPN
mkg-872	158	12	j	j	PROPN
mkg-872	158	13	,	,	PUNCT
mkg-872	158	14	marjanovic	marjanovic	PROPN
mkg-872	158	15	m.	m.	NOUN
mkg-872	158	16	salivary	salivary	VERB
mkg-872	158	17	enzymes	enzyme	NOUN
mkg-872	158	18	and	and	CCONJ
mkg-872	158	19	periodontal	periodontal	ADJ
mkg-872	158	20	disease	disease	NOUN
mkg-872	158	21	.	.	PUNCT
mkg-872	159	1	med	med	ADJ
mkg-872	159	2	oral	oral	ADJ
mkg-872	159	3	patol	patol	NOUN
mkg-872	159	4	oral	oral	ADJ
mkg-872	159	5	cir	cir	NOUN
mkg-872	159	6	bucal	bucal	NOUN
mkg-872	159	7	2006	2006	NUM
mkg-872	159	8	;	;	PUNCT
mkg-872	159	9	11	11	NUM
mkg-872	159	10	:	:	PUNCT
mkg-872	159	11	e115–9	e115–9	NOUN
mkg-872	159	12	.	.	PUNCT
mkg-872	160	1	20	20	NUM
mkg-872	160	2	.	.	PUNCT
mkg-872	160	3	zappacosta	zappacosta	PROPN
mkg-872	160	4	b	b	PROPN
mkg-872	160	5	,	,	PUNCT
mkg-872	160	6	manni	manni	PROPN
mkg-872	160	7	a	a	PROPN
mkg-872	160	8	,	,	PUNCT
mkg-872	160	9	persichilli	persichilli	PROPN
mkg-872	160	10	s	s	PART
mkg-872	160	11	,	,	PUNCT
mkg-872	160	12	boari	boari	PROPN
mkg-872	160	13	a	a	X
mkg-872	160	14	,	,	PUNCT
mkg-872	160	15	scribano	scribano	ADJ
mkg-872	160	16	d	d	PROPN
mkg-872	160	17	,	,	PUNCT
mkg-872	160	18	minucci	minucci	VERB
mkg-872	160	19	a	a	PRON
mkg-872	160	20	,	,	PUNCT
mkg-872	160	21	raffaelli	raffaelli	NOUN
mkg-872	160	22	l	l	NOUN
mkg-872	160	23	,	,	PUNCT
mkg-872	160	24	giardina	giardina	PROPN
mkg-872	160	25	b	b	PROPN
mkg-872	160	26	,	,	PUNCT
mkg-872	160	27	sole	sole	ADJ
mkg-872	160	28	pd	pd	NOUN
mkg-872	160	29	.	.	PROPN
mkg-872	160	30	salivary	salivary	ADJ
mkg-872	160	31	thiols	thiol	NOUN
mkg-872	160	32	and	and	CCONJ
mkg-872	160	33	enzyme	enzyme	NOUN
mkg-872	160	34	markers	marker	NOUN
mkg-872	160	35	of	of	ADP
mkg-872	160	36	cell	cell	NOUN
mkg-872	160	37	damage	damage	NOUN
mkg-872	160	38	in	in	ADP
mkg-872	160	39	periodontal	periodontal	ADJ
mkg-872	160	40	disease	disease	NOUN
mkg-872	160	41	.	.	PUNCT
mkg-872	161	1	clinical	clinical	ADJ
mkg-872	161	2	biochemistry	biochemistry	NOUN
mkg-872	161	3	2007	2007	NUM
mkg-872	161	4	;	;	PUNCT
mkg-872	161	5	40(9–10	40(9–10	NUM
mkg-872	161	6	):	):	PUNCT
mkg-872	161	7	661–5	661–5	NUM
mkg-872	161	8	.	.	PUNCT
mkg-872	162	1	21	21	NUM
mkg-872	162	2	.	.	PUNCT
mkg-872	163	1	kumar	kumar	PROPN
mkg-872	163	2	r	r	PROPN
mkg-872	163	3	,	,	PUNCT
mkg-872	163	4	sharma	sharma	PROPN
mkg-872	163	5	g.	g.	PROPN
mkg-872	163	6	salivary	salivary	PROPN
mkg-872	163	7	alkaline	alkaline	NOUN
mkg-872	163	8	phosphatase	phosphatase	NOUN
mkg-872	163	9	level	level	NOUN
mkg-872	163	10	as	as	ADP
mkg-872	163	11	diagnostic	diagnostic	ADJ
mkg-872	163	12	marker	marker	NOUN
mkg-872	163	13	for	for	ADP
mkg-872	163	14	periodontal	periodontal	ADJ
mkg-872	163	15	disease	disease	NOUN
mkg-872	163	16	.	.	PUNCT
mkg-872	164	1	j	j	PROPN
mkg-872	164	2	int	int	PROPN
mkg-872	164	3	oral	oral	ADJ
mkg-872	164	4	health	health	NOUN
mkg-872	164	5	2011	2011	NUM
mkg-872	164	6	;	;	PUNCT
mkg-872	164	7	3(issue	3(issue	NUM
mkg-872	164	8	5	5	NUM
mkg-872	164	9	):	):	PUNCT
mkg-872	164	10	81–6	81–6	PROPN
mkg-872	164	11	.	.	PUNCT
mkg-872	164	12	22	22	NUM
mkg-872	164	13	.	.	PUNCT
mkg-872	165	1	ruhl	ruhl	PROPN
mkg-872	165	2	s	s	PROPN
mkg-872	165	3	,	,	PUNCT
mkg-872	165	4	hamberger	hamberger	NOUN
mkg-872	165	5	s	s	PROPN
mkg-872	165	6	,	,	PUNCT
mkg-872	165	7	betz	betz	NOUN
mkg-872	165	8	r	r	PROPN
mkg-872	165	9	,	,	PUNCT
mkg-872	165	10	sukkar	sukkar	NOUN
mkg-872	165	11	t	t	PROPN
mkg-872	165	12	,	,	PUNCT
mkg-872	165	13	schmalz	schmalz	PROPN
mkg-872	165	14	g	g	PROPN
mkg-872	165	15	,	,	PUNCT
mkg-872	165	16	seymour	seymour	PROPN
mkg-872	165	17	ra	ra	PROPN
mkg-872	165	18	,	,	PUNCT
mkg-872	165	19	hiller	hiller	PROPN
mkg-872	165	20	ka	ka	PROPN
mkg-872	165	21	,	,	PUNCT
mkg-872	165	22	thomason	thomason	PROPN
mkg-872	165	23	jm	jm	PROPN
mkg-872	165	24	.	.	PROPN
mkg-872	165	25	salivary	salivary	ADJ
mkg-872	165	26	composition	composition	NOUN
mkg-872	165	27	in	in	ADP
mkg-872	165	28	gingival	gingival	ADJ
mkg-872	165	29	overgrowth	overgrowth	NOUN
mkg-872	165	30	.	.	PUNCT
mkg-872	166	1	j	j	PROPN
mkg-872	166	2	dent	dent	NOUN
mkg-872	166	3	res	re	NOUN
mkg-872	166	4	2004	2004	NUM
mkg-872	166	5	;	;	PUNCT
mkg-872	166	6	83(4	83(4	NUM
mkg-872	166	7	):	):	PUNCT
mkg-872	166	8	322–6	322–6	NUM
mkg-872	166	9	.	.	PROPN
mkg-872	166	10	23	23	NUM
mkg-872	166	11	.	.	PUNCT
mkg-872	167	1	bascones	bascone	NOUN
mkg-872	167	2	-	-	PUNCT
mkg-872	167	3	martinez	martinez	PROPN
mkg-872	167	4	a	a	X
mkg-872	167	5	,	,	PUNCT
mkg-872	167	6	munoz	munoz	PROPN
mkg-872	167	7	-	-	PUNCT
mkg-872	167	8	corcuera	corcuera	NOUN
mkg-872	167	9	m	m	NOUN
mkg-872	167	10	,	,	PUNCT
mkg-872	167	11	noronha	noronha	NOUN
mkg-872	167	12	s	s	PART
mkg-872	167	13	,	,	PUNCT
mkg-872	167	14	mota	mota	PROPN
mkg-872	167	15	p	p	NOUN
mkg-872	167	16	,	,	PUNCT
mkg-872	167	17	basconez	basconez	ADJ
mkg-872	167	18	-	-	PUNCT
mkg-872	167	19	ilundain	ilundain	ADJ
mkg-872	167	20	c	c	NOUN
mkg-872	167	21	,	,	PUNCT
mkg-872	167	22	campo	campo	NOUN
mkg-872	167	23	-	-	PUNCT
mkg-872	167	24	trapero	trapero	NOUN
mkg-872	167	25	j.	j.	PROPN
mkg-872	167	26	host	host	NOUN
mkg-872	167	27	defence	defence	NOUN
mkg-872	167	28	mechanisms	mechanism	NOUN
mkg-872	167	29	against	against	ADP
mkg-872	167	30	bacterial	bacterial	ADJ
mkg-872	167	31	aggression	aggression	NOUN
mkg-872	167	32	in	in	ADP
mkg-872	167	33	periodontal	periodontal	ADJ
mkg-872	167	34	disease	disease	NOUN
mkg-872	167	35	:	:	PUNCT
mkg-872	167	36	basic	basic	ADJ
mkg-872	167	37	mechanisms	mechanism	NOUN
mkg-872	167	38	.	.	PUNCT
mkg-872	168	1	med	med	ADJ
mkg-872	168	2	oral	oral	ADJ
mkg-872	168	3	pathol	pathol	NOUN
mkg-872	168	4	oral	oral	ADJ
mkg-872	168	5	cir	cir	NOUN
mkg-872	168	6	bucal	bucal	NOUN
mkg-872	168	7	2009	2009	NUM
mkg-872	168	8	;	;	PUNCT
mkg-872	168	9	14(12	14(12	NUM
mkg-872	168	10	):	):	PUNCT
mkg-872	168	11	e680–5	e680–5	NOUN
mkg-872	168	12	.	.	PUNCT
mkg-872	169	1	24	24	NUM
mkg-872	169	2	.	.	PUNCT
mkg-872	169	3	bascones	bascone	NOUN
mkg-872	169	4	martínez	martínez	PROPN
mkg-872	169	5	a	a	PROPN
mkg-872	169	6	,	,	PUNCT
mkg-872	169	7	figuero	figuero	PROPN
mkg-872	169	8	ruiz	ruiz	PROPN
mkg-872	169	9	e.	e.	PROPN
mkg-872	169	10	periodontal	periodontal	PROPN
mkg-872	169	11	diseases	disease	NOUN
mkg-872	169	12	as	as	ADP
mkg-872	169	13	bacterial	bacterial	ADJ
mkg-872	169	14	infection	infection	NOUN
mkg-872	169	15	.	.	PUNCT
mkg-872	170	1	av	av	PROPN
mkg-872	170	2	periodon	periodon	PROPN
mkg-872	170	3	implantol	implantol	ADV
mkg-872	170	4	.	.	PUNCT
mkg-872	171	1	2005	2005	NUM
mkg-872	171	2	;	;	PUNCT
mkg-872	171	3	17(3	17(3	NUM
mkg-872	171	4	):	):	PUNCT
mkg-872	171	5	111–8	111–8	NOUN
mkg-872	171	6	.	.	PUNCT
mkg-872	172	1	25	25	NUM
mkg-872	172	2	.	.	PUNCT
mkg-872	173	1	kesic	kesic	PROPN
mkg-872	173	2	l	l	PROPN
mkg-872	173	3	,	,	PUNCT
mkg-872	173	4	milasin	milasin	PROPN
mkg-872	173	5	j	j	PROPN
mkg-872	173	6	,	,	PUNCT
mkg-872	173	7	igic	igic	PROPN
mkg-872	173	8	m	m	PROPN
mkg-872	173	9	,	,	PUNCT
mkg-872	173	10	obradovic	obradovic	PROPN
mkg-872	173	11	r.	r.	PROPN
mkg-872	173	12	microbial	microbial	PROPN
mkg-872	173	13	etiology	etiology	NOUN
mkg-872	173	14	of	of	ADP
mkg-872	173	15	periodontal	periodontal	ADJ
mkg-872	173	16	diseases	disease	NOUN
mkg-872	173	17	–	–	PUNCT
mkg-872	173	18	mini	mini	ADJ
mkg-872	173	19	review	review	NOUN
mkg-872	173	20	.	.	PUNCT
mkg-872	174	1	medicine	medicine	NOUN
mkg-872	174	2	and	and	CCONJ
mkg-872	174	3	biology	biology	NOUN
mkg-872	174	4	2008	2008	NUM
mkg-872	174	5	;	;	PUNCT
mkg-872	174	6	15(1	15(1	NUM
mkg-872	174	7	):	):	PUNCT
mkg-872	174	8	1–6	1–6	NUM
mkg-872	174	9	.	.	NOUN
mkg-872	174	10	26	26	NUM
mkg-872	174	11	.	.	PUNCT
mkg-872	175	1	ramseier	ramseier	PROPN
mkg-872	175	2	ca	ca	PROPN
mkg-872	175	3	,	,	PUNCT
mkg-872	175	4	kinney	kinney	PROPN
mkg-872	175	5	js	js	PROPN
mkg-872	175	6	,	,	PUNCT
mkg-872	175	7	herr	herr	PROPN
mkg-872	175	8	ae	ae	PROPN
mkg-872	175	9	,	,	PUNCT
mkg-872	175	10	thomas	thomas	PROPN
mkg-872	175	11	braun	braun	PROPN
mkg-872	175	12	t	t	PROPN
mkg-872	175	13	,	,	PUNCT
mkg-872	175	14	sugai	sugai	NOUN
mkg-872	175	15	jv	jv	NOUN
mkg-872	175	16	,	,	PUNCT
mkg-872	175	17	shelburne	shelburne	NOUN
mkg-872	175	18	ca	ca	NOUN
mkg-872	175	19	,	,	PUNCT
mkg-872	175	20	rayburn	rayburn	PROPN
mkg-872	175	21	la	la	PROPN
mkg-872	175	22	,	,	PUNCT
mkg-872	175	23	tran	tran	PROPN
mkg-872	175	24	hm	hm	PROPN
mkg-872	175	25	,	,	PUNCT
mkg-872	175	26	singh	singh	PROPN
mkg-872	175	27	ak	ak	PROPN
mkg-872	175	28	,	,	PUNCT
mkg-872	175	29	giannobile	giannobile	PROPN
mkg-872	175	30	wv	wv	PROPN
mkg-872	175	31	.	.	PUNCT
mkg-872	175	32	identification	identification	NOUN
mkg-872	175	33	of	of	ADP
mkg-872	175	34	pathogen	pathogen	NOUN
mkg-872	175	35	and	and	CCONJ
mkg-872	175	36	host	host	NOUN
mkg-872	175	37	-	-	PUNCT
mkg-872	175	38	response	response	NOUN
mkg-872	175	39	markers	marker	NOUN
mkg-872	175	40	correlated	correlate	VERB
mkg-872	175	41	with	with	ADP
mkg-872	175	42	periodontal	periodontal	ADJ
mkg-872	175	43	disease	disease	NOUN
mkg-872	175	44	.	.	PUNCT
mkg-872	176	1	j	j	PROPN
mkg-872	176	2	periodontol	periodontol	PROPN
mkg-872	176	3	2009	2009	NUM
mkg-872	176	4	;	;	PUNCT
mkg-872	176	5	80	80	NUM
mkg-872	176	6	:	:	PUNCT
mkg-872	176	7	436–46	436–46	NUM
mkg-872	176	8	.	.	PUNCT
mkg-872	177	1	27	27	NUM
mkg-872	177	2	.	.	PUNCT
mkg-872	178	1	zia	zia	PROPN
mkg-872	178	2	a	a	PROPN
mkg-872	178	3	,	,	PUNCT
mkg-872	178	4	khan	khan	PROPN
mkg-872	178	5	s	s	PART
mkg-872	178	6	,	,	PUNCT
mkg-872	178	7	bey	bey	PROPN
mkg-872	178	8	a	a	PRON
mkg-872	178	9	,	,	PUNCT
mkg-872	178	10	gupta	gupta	PROPN
mkg-872	178	11	nd	nd	NUM
mkg-872	178	12	,	,	PUNCT
mkg-872	178	13	mukhtar	mukhtar	PROPN
mkg-872	178	14	-	-	PUNCT
mkg-872	178	15	un	un	PROPN
mkg-872	178	16	-	-	ADJ
mkg-872	178	17	nisar	nisar	ADJ
mkg-872	178	18	s.	s.	PROPN
mkg-872	178	19	oral	oral	ADJ
mkg-872	178	20	biomarkers	biomarker	NOUN
mkg-872	178	21	in	in	ADP
mkg-872	178	22	the	the	DET
mkg-872	178	23	diagnosis	diagnosis	NOUN
mkg-872	178	24	and	and	CCONJ
mkg-872	178	25	progression	progression	NOUN
mkg-872	178	26	of	of	ADP
mkg-872	178	27	periodontal	periodontal	ADJ
mkg-872	178	28	diseases	disease	NOUN
mkg-872	178	29	.	.	PUNCT
mkg-872	179	1	biology	biology	NOUN
mkg-872	179	2	and	and	CCONJ
mkg-872	179	3	medicine	medicine	NOUN
mkg-872	179	4	2011	2011	NUM
mkg-872	179	5	march	march	NOUN
mkg-872	179	6	;	;	PUNCT
mkg-872	179	7	3(2	3(2	NUM
mkg-872	179	8	):	):	PUNCT
mkg-872	179	9	45–52	45–52	NUM
mkg-872	179	10	.	.	PUNCT
mkg-872	180	1	28	28	NUM
mkg-872	180	2	.	.	PUNCT
mkg-872	181	1	seibel	seibel	PROPN
mkg-872	181	2	mj	mj	PROPN
mkg-872	181	3	.	.	PROPN
mkg-872	182	1	clinical	clinical	ADJ
mkg-872	182	2	application	application	NOUN
mkg-872	182	3	of	of	ADP
mkg-872	182	4	biochemical	biochemical	ADJ
mkg-872	182	5	markers	marker	NOUN
mkg-872	182	6	of	of	ADP
mkg-872	182	7	bone	bone	NOUN
mkg-872	182	8	turnover	turnover	NOUN
mkg-872	182	9	.	.	PUNCT
mkg-872	183	1	arq	arq	PROPN
mkg-872	183	2	bras	bras	PROPN
mkg-872	183	3	endocrinol	endocrinol	VERB
mkg-872	183	4	metabol	metabol	NOUN
mkg-872	183	5	2006	2006	NUM
mkg-872	183	6	;	;	PUNCT
mkg-872	183	7	50	50	NUM
mkg-872	183	8	:	:	PUNCT
mkg-872	183	9	603–20	603–20	NUM
mkg-872	183	10	.	.	PROPN
mkg-872	183	11	29	29	NUM
mkg-872	183	12	.	.	PUNCT
mkg-872	184	1	mcgehee	mcgehee	PROPN
mkg-872	184	2	jr	jr	PROPN
mkg-872	184	3	.	.	PROPN
mkg-872	185	1	jw	jw	PROPN
mkg-872	185	2	,	,	PUNCT
mkg-872	185	3	johnson	johnson	PROPN
mkg-872	185	4	rb	rb	PROPN
mkg-872	185	5	.	.	PUNCT
mkg-872	186	1	biomarkers	biomarker	NOUN
mkg-872	186	2	of	of	ADP
mkg-872	186	3	bone	bone	NOUN
mkg-872	186	4	turnover	turnover	NOUN
mkg-872	186	5	can	can	AUX
mkg-872	186	6	be	be	AUX
mkg-872	186	7	assayed	assayed	ADJ
mkg-872	186	8	from	from	ADP
mkg-872	186	9	human	human	ADJ
mkg-872	186	10	saliva	saliva	NOUN
mkg-872	186	11	.	.	PUNCT
mkg-872	187	1	the	the	DET
mkg-872	187	2	journals	journal	NOUN
mkg-872	187	3	of	of	ADP
mkg-872	187	4	gerontology	gerontology	NOUN
mkg-872	187	5	:	:	PUNCT
mkg-872	187	6	series	series	PROPN
mkg-872	187	7	a	a	DET
mkg-872	187	8	2003	2003	NUM
mkg-872	187	9	;	;	PUNCT
mkg-872	187	10	59	59	NUM
mkg-872	187	11	(	(	PUNCT
mkg-872	187	12	issue	issue	NOUN
mkg-872	187	13	3	3	NUM
mkg-872	187	14	):	):	PUNCT
mkg-872	187	15	b196–200	b196–200	PROPN
mkg-872	187	16	.	.	PROPN
mkg-872	187	17	30	30	NUM
mkg-872	187	18	.	.	PUNCT
mkg-872	188	1	frodge	frodge	PROPN
mkg-872	188	2	bd	bd	PROPN
mkg-872	188	3	,	,	PUNCT
mkg-872	188	4	ebersole	ebersole	PROPN
mkg-872	188	5	jl	jl	PROPN
mkg-872	188	6	,	,	PUNCT
mkg-872	188	7	kryscio	kryscio	PROPN
mkg-872	188	8	rj	rj	PROPN
mkg-872	188	9	,	,	PUNCT
mkg-872	188	10	thomas	thomas	PROPN
mkg-872	188	11	mv	mv	PROPN
mkg-872	188	12	,	,	PUNCT
mkg-872	188	13	miller	miller	PROPN
mkg-872	188	14	cs	cs	PROPN
mkg-872	188	15	.	.	PROPN
mkg-872	188	16	bone	bone	NOUN
mkg-872	188	17	remodeling	remodel	VERB
mkg-872	188	18	biomarkers	biomarker	NOUN
mkg-872	188	19	of	of	ADP
mkg-872	188	20	periodontal	periodontal	ADJ
mkg-872	188	21	disease	disease	NOUN
mkg-872	188	22	in	in	ADP
mkg-872	188	23	saliva	saliva	NOUN
mkg-872	188	24	.	.	PUNCT
mkg-872	189	1	j	j	PROPN
mkg-872	189	2	periodontol	periodontol	PROPN
mkg-872	189	3	2008	2008	NUM
mkg-872	189	4	;	;	PUNCT
mkg-872	189	5	79	79	NUM
mkg-872	189	6	:	:	PUNCT
mkg-872	189	7	1913–9	1913–9	NUM
mkg-872	189	8	.	.	PUNCT