id	sid	tid	token	lemma	pos
dentistry3000-808	1	1	808	808	NUM
dentistry3000-808	1	2	final	final	ADJ
dentistry3000-808	1	3	poten&al	poten&al	PROPN
dentistry3000-808	1	4	role	role	NOUN
dentistry3000-808	1	5	of	of	ADP
dentistry3000-808	1	6	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	1	7	in	in	ADP
dentistry3000-808	1	8	rheumatoid	rheumatoid	NOUN
dentistry3000-808	1	9	arthri&s	arthri&s	PROPN
dentistry3000-808	1	10	vol	vol	NOUN
dentistry3000-808	1	11	13	13	NUM
dentistry3000-808	1	12	no	no	DET
dentistry3000-808	1	13	1	1	NUM
dentistry3000-808	1	14	(	(	PUNCT
dentistry3000-808	1	15	2025	2025	NUM
dentistry3000-808	1	16	)	)	PUNCT
dentistry3000-808	1	17	doi	doi	NOUN
dentistry3000-808	1	18	10.5195	10.5195	NUM
dentistry3000-808	1	19	/	/	SYM
dentistry3000-808	1	20	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	1	21	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	1	22	potential	potential	ADJ
dentistry3000-808	1	23	role	role	NOUN
dentistry3000-808	1	24	of	of	ADP
dentistry3000-808	1	25	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	1	26	in	in	ADP
dentistry3000-808	1	27	rheumatoid	rheumatoid	NOUN
dentistry3000-808	1	28	arthritis	arthritis	NOUN
dentistry3000-808	1	29	shaymaa	shaymaa	NOUN
dentistry3000-808	1	30	abdulkareem	abdulkareem	NOUN
dentistry3000-808	1	31	nori	nori	NOUN
dentistry3000-808	1	32	,	,	PUNCT
dentistry3000-808	1	33	batool	batool	PROPN
dentistry3000-808	1	34	hassan	hassan	PROPN
dentistry3000-808	1	35	al	al	PROPN
dentistry3000-808	1	36	-	-	PUNCT
dentistry3000-808	1	37	ghurabi	ghurabi	PROPN
dentistry3000-808	1	38	college	college	PROPN
dentistry3000-808	1	39	of	of	ADP
dentistry3000-808	1	40	dentistry	dentistry	NOUN
dentistry3000-808	1	41	,	,	PUNCT
dentistry3000-808	1	42	university	university	NOUN
dentistry3000-808	1	43	of	of	ADP
dentistry3000-808	1	44	baghdad	baghdad	PROPN
dentistry3000-808	1	45	,	,	PUNCT
dentistry3000-808	1	46	iraq	iraq	PROPN
dentistry3000-808	1	47	abstract	abstract	ADJ
dentistry3000-808	1	48	periodontal	periodontal	ADJ
dentistry3000-808	1	49	disease	disease	NOUN
dentistry3000-808	1	50	,	,	PUNCT
dentistry3000-808	1	51	par	par	NOUN
dentistry3000-808	1	52	/	/	SYM
dentistry3000-808	1	53	cularly	cularly	ADV
dentistry3000-808	1	54	the	the	DET
dentistry3000-808	1	55	chronic	chronic	ADJ
dentistry3000-808	1	56	form	form	NOUN
dentistry3000-808	1	57	of	of	ADP
dentistry3000-808	1	58	periodon//s	periodon//	NOUN
dentistry3000-808	1	59	,	,	PUNCT
dentistry3000-808	1	60	is	be	AUX
dentistry3000-808	1	61	a	a	DET
dentistry3000-808	1	62	widespread	widespread	ADJ
dentistry3000-808	1	63	inflammatory	inflammatory	ADJ
dentistry3000-808	1	64	condi	condi	NOUN
dentistry3000-808	1	65	/	/	SYM
dentistry3000-808	1	66	on	on	ADP
dentistry3000-808	1	67	caused	cause	VERB
dentistry3000-808	1	68	by	by	ADP
dentistry3000-808	1	69	pathogenic	pathogenic	ADJ
dentistry3000-808	1	70	bacteria	bacteria	NOUN
dentistry3000-808	1	71	,	,	PUNCT
dentistry3000-808	1	72	such	such	ADJ
dentistry3000-808	1	73	as	as	ADP
dentistry3000-808	1	74	porphyromonas	porphyromona	NOUN
dentistry3000-808	1	75	gingivalis	gingivalis	PROPN
dentistry3000-808	1	76	.	.	PUNCT
dentistry3000-808	2	1	this	this	DET
dentistry3000-808	2	2	review	review	NOUN
dentistry3000-808	2	3	explores	explore	VERB
dentistry3000-808	2	4	the	the	DET
dentistry3000-808	2	5	poten	poten	ADJ
dentistry3000-808	2	6	/	/	SYM
dentistry3000-808	2	7	al	al	PROPN
dentistry3000-808	2	8	role	role	NOUN
dentistry3000-808	2	9	of	of	ADP
dentistry3000-808	2	10	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	2	11	,	,	PUNCT
dentistry3000-808	2	12	par	par	ADJ
dentistry3000-808	2	13	/	/	SYM
dentistry3000-808	2	14	cularly	cularly	ADV
dentistry3000-808	2	15	porphyromonas	porphyromona	NOUN
dentistry3000-808	2	16	gingivalis	gingivalis	PROPN
dentistry3000-808	2	17	,	,	PUNCT
dentistry3000-808	2	18	in	in	ADP
dentistry3000-808	2	19	the	the	DET
dentistry3000-808	2	20	development	development	NOUN
dentistry3000-808	2	21	and	and	CCONJ
dentistry3000-808	2	22	progression	progression	NOUN
dentistry3000-808	2	23	of	of	ADP
dentistry3000-808	2	24	rheumatoid	rheumatoid	PROPN
dentistry3000-808	2	25	arthri	arthri	PROPN
dentistry3000-808	2	26	/	/	SYM
dentistry3000-808	2	27	s.	s.	PROPN
dentistry3000-808	2	28	rheumatoid	rheumatoid	PROPN
dentistry3000-808	2	29	arthri	arthri	PROPN
dentistry3000-808	2	30	/	/	SYM
dentistry3000-808	2	31	s	s	PROPN
dentistry3000-808	2	32	is	be	AUX
dentistry3000-808	2	33	a	a	DET
dentistry3000-808	2	34	systemic	systemic	ADJ
dentistry3000-808	2	35	autoimmune	autoimmune	ADJ
dentistry3000-808	2	36	disorder	disorder	NOUN
dentistry3000-808	2	37	characterized	characterize	VERB
dentistry3000-808	2	38	by	by	ADP
dentistry3000-808	2	39	joint	joint	ADJ
dentistry3000-808	2	40	inflamma	inflamma	PROPN
dentistry3000-808	2	41	/	/	SYM
dentistry3000-808	2	42	on	on	ADP
dentistry3000-808	2	43	and	and	CCONJ
dentistry3000-808	2	44	damage	damage	NOUN
dentistry3000-808	2	45	.	.	PUNCT
dentistry3000-808	3	1	both	both	DET
dentistry3000-808	3	2	periodon//s	periodon//	NOUN
dentistry3000-808	3	3	and	and	CCONJ
dentistry3000-808	3	4	rheumatoid	rheumatoid	VERB
dentistry3000-808	3	5	arthri	arthri	PROPN
dentistry3000-808	3	6	/	/	SYM
dentistry3000-808	3	7	s	s	PART
dentistry3000-808	3	8	share	share	NOUN
dentistry3000-808	3	9	common	common	ADJ
dentistry3000-808	3	10	inflammatory	inflammatory	ADJ
dentistry3000-808	3	11	mechanisms	mechanism	NOUN
dentistry3000-808	3	12	,	,	PUNCT
dentistry3000-808	3	13	driven	drive	VERB
dentistry3000-808	3	14	by	by	ADP
dentistry3000-808	3	15	proinflammatory	proinflammatory	ADJ
dentistry3000-808	3	16	cytokines	cytokine	NOUN
dentistry3000-808	3	17	and	and	CCONJ
dentistry3000-808	3	18	immune	immune	ADJ
dentistry3000-808	3	19	dysregula	dysregula	NOUN
dentistry3000-808	3	20	/	/	SYM
dentistry3000-808	3	21	on	on	ADP
dentistry3000-808	3	22	.	.	PUNCT
dentistry3000-808	4	1	porphyromonas	porphyromona	NOUN
dentistry3000-808	4	2	gingivalis	gingivalis	PROPN
dentistry3000-808	4	3	,	,	PUNCT
dentistry3000-808	4	4	via	via	ADP
dentistry3000-808	4	5	its	its	PRON
dentistry3000-808	4	6	pathogenic	pathogenic	ADJ
dentistry3000-808	4	7	determinants	determinant	NOUN
dentistry3000-808	4	8	,	,	PUNCT
dentistry3000-808	4	9	that	that	ADV
dentistry3000-808	4	10	is	is	ADV
dentistry3000-808	4	11	,	,	PUNCT
dentistry3000-808	4	12	gingipains	gingipain	NOUN
dentistry3000-808	4	13	and	and	CCONJ
dentistry3000-808	4	14	pep	pep	NOUN
dentistry3000-808	4	15	/	/	SYM
dentistry3000-808	4	16	dyl	dyl	PROPN
dentistry3000-808	4	17	arginine	arginine	NOUN
dentistry3000-808	4	18	deiminase	deiminase	VERB
dentistry3000-808	4	19	,	,	PUNCT
dentistry3000-808	4	20	facilitates	facilitate	VERB
dentistry3000-808	4	21	the	the	DET
dentistry3000-808	4	22	citrullina	citrullina	PROPN
dentistry3000-808	4	23	/	/	SYM
dentistry3000-808	4	24	on	on	ADP
dentistry3000-808	4	25	of	of	ADP
dentistry3000-808	4	26	proteins	protein	NOUN
dentistry3000-808	4	27	,	,	PUNCT
dentistry3000-808	4	28	leading	lead	VERB
dentistry3000-808	4	29	to	to	ADP
dentistry3000-808	4	30	the	the	DET
dentistry3000-808	4	31	genera	genera	NOUN
dentistry3000-808	4	32	/	/	PUNCT
dentistry3000-808	4	33	on	on	ADP
dentistry3000-808	4	34	of	of	ADP
dentistry3000-808	4	35	an/-citrullinated	an/-citrullinate	VERB
dentistry3000-808	4	36	protein	protein	NOUN
dentistry3000-808	4	37	an	an	DET
dentistry3000-808	4	38	/	/	SYM
dentistry3000-808	4	39	bodies	body	NOUN
dentistry3000-808	4	40	,	,	PUNCT
dentistry3000-808	4	41	a	a	DET
dentistry3000-808	4	42	key	key	ADJ
dentistry3000-808	4	43	feature	feature	NOUN
dentistry3000-808	4	44	in	in	ADP
dentistry3000-808	4	45	rheumatoid	rheumatoid	PROPN
dentistry3000-808	4	46	arthri	arthri	PROPN
dentistry3000-808	4	47	/	/	SYM
dentistry3000-808	4	48	s	s	PART
dentistry3000-808	4	49	pathogenesis	pathogenesis	NOUN
dentistry3000-808	4	50	.	.	PUNCT
dentistry3000-808	5	1	the	the	DET
dentistry3000-808	5	2	reciprocal	reciprocal	ADJ
dentistry3000-808	5	3	rela	rela	PROPN
dentistry3000-808	5	4	/	/	SYM
dentistry3000-808	5	5	onship	onship	NOUN
dentistry3000-808	5	6	between	between	ADP
dentistry3000-808	5	7	periodon//s	periodon//	NOUN
dentistry3000-808	5	8	and	and	CCONJ
dentistry3000-808	5	9	rheumatoid	rheumatoid	VERB
dentistry3000-808	5	10	arthri	arthri	PROPN
dentistry3000-808	5	11	/	/	SYM
dentistry3000-808	5	12	s	s	PART
dentistry3000-808	5	13	is	be	AUX
dentistry3000-808	5	14	further	far	ADV
dentistry3000-808	5	15	supported	support	VERB
dentistry3000-808	5	16	through	through	ADP
dentistry3000-808	5	17	evidence	evidence	NOUN
dentistry3000-808	5	18	showing	show	VERB
dentistry3000-808	5	19	that	that	SCONJ
dentistry3000-808	5	20	individuals	individual	NOUN
dentistry3000-808	5	21	with	with	ADP
dentistry3000-808	5	22	periodon//s	periodon//	NOUN
dentistry3000-808	5	23	are	be	AUX
dentistry3000-808	5	24	at	at	ADP
dentistry3000-808	5	25	a	a	DET
dentistry3000-808	5	26	higher	high	ADJ
dentistry3000-808	5	27	risk	risk	NOUN
dentistry3000-808	5	28	for	for	ADP
dentistry3000-808	5	29	rheumatoid	rheumatoid	NOUN
dentistry3000-808	5	30	arthri	arthri	PROPN
dentistry3000-808	5	31	/	/	SYM
dentistry3000-808	5	32	s	s	PROPN
dentistry3000-808	5	33	,	,	PUNCT
dentistry3000-808	5	34	and	and	CCONJ
dentistry3000-808	5	35	vice	vice	ADV
dentistry3000-808	5	36	versa	versa	ADV
dentistry3000-808	5	37	.	.	PUNCT
dentistry3000-808	6	1	both	both	DET
dentistry3000-808	6	2	circumstances	circumstance	NOUN
dentistry3000-808	6	3	exhibit	exhibit	VERB
dentistry3000-808	6	4	similar	similar	ADJ
dentistry3000-808	6	5	inflammatory	inflammatory	ADJ
dentistry3000-808	6	6	pathways	pathway	NOUN
dentistry3000-808	6	7	,	,	PUNCT
dentistry3000-808	6	8	involving	involve	VERB
dentistry3000-808	6	9	cytokines	cytokine	NOUN
dentistry3000-808	6	10	like	like	ADP
dentistry3000-808	6	11	tumor	tumor	NOUN
dentistry3000-808	6	12	necrosis	necrosis	NOUN
dentistry3000-808	6	13	factor	factor	NOUN
dentistry3000-808	6	14	alpha	alpha	NOUN
dentistry3000-808	6	15	,	,	PUNCT
dentistry3000-808	6	16	interleukin	interleukin	NOUN
dentistry3000-808	6	17	1	1	NUM
dentistry3000-808	6	18	and	and	CCONJ
dentistry3000-808	6	19	interleukin	interleukin	NOUN
dentistry3000-808	6	20	6	6	NUM
dentistry3000-808	6	21	and	and	CCONJ
dentistry3000-808	6	22	/ssue	/ssue	ADV
dentistry3000-808	6	23	degrada	degrada	PROPN
dentistry3000-808	6	24	/	/	SYM
dentistry3000-808	6	25	on	on	ADP
dentistry3000-808	6	26	mediated	mediate	VERB
dentistry3000-808	6	27	by	by	ADP
dentistry3000-808	6	28	matrix	matrix	NOUN
dentistry3000-808	6	29	metalloproteinases	metalloproteinase	NOUN
dentistry3000-808	6	30	.	.	PUNCT
dentistry3000-808	7	1	keywords	keyword	NOUN
dentistry3000-808	7	2	:	:	PUNCT
dentistry3000-808	7	3	rheumatoid	rheumatoid	VERB
dentistry3000-808	7	4	arthri	arthri	PROPN
dentistry3000-808	7	5	=	=	SYM
dentistry3000-808	7	6	s	s	PROPN
dentistry3000-808	7	7	,	,	PUNCT
dentistry3000-808	7	8	periodon==s	periodon==s	NOUN
dentistry3000-808	7	9	,	,	PUNCT
dentistry3000-808	7	10	porphyromonas	porphyromona	NOUN
dentistry3000-808	7	11	gingivalis	gingivali	VERB
dentistry3000-808	7	12	cita9on	cita9on	PROPN
dentistry3000-808	7	13	:	:	PUNCT
dentistry3000-808	7	14	nori	nori	PROPN
dentistry3000-808	7	15	sa	sa	PROPN
dentistry3000-808	7	16	,	,	PUNCT
dentistry3000-808	7	17	et	et	PROPN
dentistry3000-808	7	18	al	al	PROPN
dentistry3000-808	7	19	.	.	PUNCT
dentistry3000-808	8	1	poten9al	poten9al	PROPN
dentistry3000-808	8	2	role	role	NOUN
dentistry3000-808	8	3	of	of	ADP
dentistry3000-808	8	4	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	8	5	in	in	ADP
dentistry3000-808	8	6	rheumatoid	rheumatoid	NOUN
dentistry3000-808	8	7	arthri9s	arthri9s	PROPN
dentistry3000-808	8	8	.	.	PUNCT
dentistry3000-808	9	1	den9stry	den9stry	PROPN
dentistry3000-808	9	2	3000.1	3000.1	NUM
dentistry3000-808	9	3	:	:	PUNCT
dentistry3000-808	9	4	a001	a001	PROPN
dentistry3000-808	9	5	doi:10/5195	doi:10/5195	PROPN
dentistry3000-808	9	6	/	/	SYM
dentistry3000-808	9	7	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	9	8	received	receive	VERB
dentistry3000-808	9	9	:	:	PUNCT
dentistry3000-808	9	10	december	december	PROPN
dentistry3000-808	9	11	25	25	NUM
dentistry3000-808	9	12	,	,	PUNCT
dentistry3000-808	9	13	2024	2024	NUM
dentistry3000-808	9	14	accepted	accept	VERB
dentistry3000-808	9	15	:	:	PUNCT
dentistry3000-808	9	16	january	january	PROPN
dentistry3000-808	9	17	5	5	NUM
dentistry3000-808	9	18	,	,	PUNCT
dentistry3000-808	9	19	2025	2025	NUM
dentistry3000-808	9	20	published	publish	VERB
dentistry3000-808	9	21	:	:	PUNCT
dentistry3000-808	9	22	february	february	PROPN
dentistry3000-808	9	23	14	14	NUM
dentistry3000-808	9	24	,	,	PUNCT
dentistry3000-808	9	25	2025	2025	NUM
dentistry3000-808	9	26	copyright	copyright	NOUN
dentistry3000-808	9	27	:	:	PUNCT
dentistry3000-808	10	1	©	©	PROPN
dentistry3000-808	10	2	2025	2025	NUM
dentistry3000-808	10	3	nori	nori	PROPN
dentistry3000-808	10	4	sa	sa	PROPN
dentistry3000-808	10	5	,	,	PUNCT
dentistry3000-808	10	6	et	et	PROPN
dentistry3000-808	10	7	al	al	PROPN
dentistry3000-808	10	8	.	.	PUNCT
dentistry3000-808	11	1	this	this	PRON
dentistry3000-808	11	2	is	be	AUX
dentistry3000-808	11	3	an	an	DET
dentistry3000-808	11	4	open	open	ADJ
dentistry3000-808	11	5	access	access	NOUN
dentistry3000-808	11	6	ar9cle	ar9cle	NOUN
dentistry3000-808	11	7	licensed	license	VERB
dentistry3000-808	11	8	under	under	ADP
dentistry3000-808	11	9	a	a	DET
dentistry3000-808	11	10	crea9ve	crea9ve	PROPN
dentistry3000-808	11	11	commons	common	NOUN
dentistry3000-808	11	12	asribu9on	asribu9on	PROPN
dentistry3000-808	11	13	work	work	VERB
dentistry3000-808	11	14	4.0	4.0	NUM
dentistry3000-808	11	15	united	united	ADJ
dentistry3000-808	11	16	states	states	PROPN
dentistry3000-808	11	17	license	license	NOUN
dentistry3000-808	11	18	.	.	PUNCT
dentistry3000-808	12	1	email	email	NOUN
dentistry3000-808	12	2	:	:	PUNCT
dentistry3000-808	12	3	batoolamms@codental.uobaghdad.edu.iq	batoolamms@codental.uobaghdad.edu.iq	ADP
dentistry3000-808	12	4	introduction	introduction	NOUN
dentistry3000-808	12	5	periodontal	periodontal	ADJ
dentistry3000-808	12	6	disease	disease	NOUN
dentistry3000-808	12	7	,	,	PUNCT
dentistry3000-808	12	8	encompassing	encompass	VERB
dentistry3000-808	12	9	gingivitis	gingivitis	NOUN
dentistry3000-808	12	10	and	and	CCONJ
dentistry3000-808	12	11	periodontitis	periodontitis	NOUN
dentistry3000-808	12	12	(	(	PUNCT
dentistry3000-808	12	13	pd	pd	PROPN
dentistry3000-808	12	14	)	)	PUNCT
dentistry3000-808	12	15	,	,	PUNCT
dentistry3000-808	12	16	is	be	AUX
dentistry3000-808	12	17	defined	define	VERB
dentistry3000-808	12	18	by	by	ADP
dentistry3000-808	12	19	the	the	DET
dentistry3000-808	12	20	inflammation	inflammation	NOUN
dentistry3000-808	12	21	of	of	ADP
dentistry3000-808	12	22	the	the	DET
dentistry3000-808	12	23	gums	gum	NOUN
dentistry3000-808	12	24	and	and	CCONJ
dentistry3000-808	12	25	other	other	ADJ
dentistry3000-808	12	26	structures	structure	NOUN
dentistry3000-808	12	27	,	,	PUNCT
dentistry3000-808	12	28	frequently	frequently	ADV
dentistry3000-808	12	29	resulting	result	VERB
dentistry3000-808	12	30	from	from	ADP
dentistry3000-808	12	31	the	the	DET
dentistry3000-808	12	32	buildup	buildup	NOUN
dentistry3000-808	12	33	of	of	ADP
dentistry3000-808	12	34	detrimental	detrimental	ADJ
dentistry3000-808	12	35	bacteria	bacteria	NOUN
dentistry3000-808	12	36	in	in	ADP
dentistry3000-808	12	37	the	the	DET
dentistry3000-808	12	38	oral	oral	ADJ
dentistry3000-808	12	39	cavity	cavity	NOUN
dentistry3000-808	12	40	.	.	PUNCT
dentistry3000-808	13	1	specific	specific	ADJ
dentistry3000-808	13	2	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	13	3	,	,	PUNCT
dentistry3000-808	13	4	particularly	particularly	ADV
dentistry3000-808	13	5	porphyromonas	porphyromona	NOUN
dentistry3000-808	13	6	gingivalis	gingivalis	PROPN
dentistry3000-808	13	7	(	(	PUNCT
dentistry3000-808	13	8	p.	p.	NOUN
dentistry3000-808	13	9	gingivalis	gingivalis	PROPN
dentistry3000-808	13	10	)	)	PUNCT
dentistry3000-808	13	11	,	,	PUNCT
dentistry3000-808	13	12	have	have	AUX
dentistry3000-808	13	13	been	be	AUX
dentistry3000-808	13	14	associated	associate	VERB
dentistry3000-808	13	15	with	with	ADP
dentistry3000-808	13	16	the	the	DET
dentistry3000-808	13	17	onset	onset	NOUN
dentistry3000-808	13	18	and	and	CCONJ
dentistry3000-808	13	19	aggravation	aggravation	NOUN
dentistry3000-808	13	20	of	of	ADP
dentistry3000-808	13	21	systemic	systemic	ADJ
dentistry3000-808	13	22	inflammation	inflammation	NOUN
dentistry3000-808	13	23	[	[	X
dentistry3000-808	13	24	1	1	NUM
dentistry3000-808	13	25	]	]	PUNCT
dentistry3000-808	13	26	.	.	PUNCT
dentistry3000-808	14	1	rheumatoid	rheumatoid	VERB
dentistry3000-808	14	2	arthritis	arthritis	NOUN
dentistry3000-808	14	3	(	(	PUNCT
dentistry3000-808	14	4	ra	ra	NOUN
dentistry3000-808	14	5	)	)	PUNCT
dentistry3000-808	14	6	is	be	AUX
dentistry3000-808	14	7	a	a	DET
dentistry3000-808	14	8	tenacious	tenacious	ADJ
dentistry3000-808	14	9	,	,	PUNCT
dentistry3000-808	14	10	systemic	systemic	ADJ
dentistry3000-808	14	11	inflammatory	inflammatory	ADJ
dentistry3000-808	14	12	condition	condition	NOUN
dentistry3000-808	14	13	that	that	SCONJ
dentistry3000-808	14	14	principally	principally	ADV
dentistry3000-808	14	15	impacts	impact	VERB
dentistry3000-808	14	16	the	the	DET
dentistry3000-808	14	17	joints	joint	NOUN
dentistry3000-808	14	18	,	,	PUNCT
dentistry3000-808	14	19	culminating	culminate	VERB
dentistry3000-808	14	20	in	in	ADP
dentistry3000-808	14	21	pain	pain	NOUN
dentistry3000-808	14	22	,	,	PUNCT
dentistry3000-808	14	23	rigidity	rigidity	NOUN
dentistry3000-808	14	24	,	,	PUNCT
dentistry3000-808	14	25	and	and	CCONJ
dentistry3000-808	14	26	possible	possible	ADJ
dentistry3000-808	14	27	joint	joint	ADJ
dentistry3000-808	14	28	abnormalities	abnormality	NOUN
dentistry3000-808	14	29	.	.	PUNCT
dentistry3000-808	15	1	precise	precise	ADJ
dentistry3000-808	15	2	ra	ra	PROPN
dentistry3000-808	15	3	etiology	etiology	NOUN
dentistry3000-808	15	4	is	be	AUX
dentistry3000-808	15	5	unclear	unclear	ADJ
dentistry3000-808	15	6	;	;	PUNCT
dentistry3000-808	15	7	nonetheless	nonetheless	ADV
dentistry3000-808	15	8	,	,	PUNCT
dentistry3000-808	15	9	it	it	PRON
dentistry3000-808	15	10	is	be	AUX
dentistry3000-808	15	11	recognized	recognize	VERB
dentistry3000-808	15	12	to	to	PART
dentistry3000-808	15	13	engage	engage	VERB
dentistry3000-808	15	14	a	a	DET
dentistry3000-808	15	15	confluence	confluence	NOUN
dentistry3000-808	15	16	of	of	ADP
dentistry3000-808	15	17	genetic	genetic	ADJ
dentistry3000-808	15	18	,	,	PUNCT
dentistry3000-808	15	19	environmental	environmental	ADJ
dentistry3000-808	15	20	,	,	PUNCT
dentistry3000-808	15	21	and	and	CCONJ
dentistry3000-808	15	22	immune	immune	NOUN
dentistry3000-808	15	23	-	-	PUNCT
dentistry3000-808	15	24	mediated	mediate	VERB
dentistry3000-808	15	25	variables	variable	NOUN
dentistry3000-808	15	26	[	[	X
dentistry3000-808	15	27	2	2	NUM
dentistry3000-808	15	28	]	]	PUNCT
dentistry3000-808	15	29	.	.	PUNCT
dentistry3000-808	16	1	research	research	NOUN
dentistry3000-808	16	2	indicates	indicate	VERB
dentistry3000-808	16	3	that	that	SCONJ
dentistry3000-808	16	4	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	16	5	may	may	AUX
dentistry3000-808	16	6	have	have	VERB
dentistry3000-808	16	7	a	a	DET
dentistry3000-808	16	8	role	role	NOUN
dentistry3000-808	16	9	in	in	ADP
dentistry3000-808	16	10	ra	ra	PROPN
dentistry3000-808	16	11	by	by	ADP
dentistry3000-808	16	12	generating	generate	VERB
dentistry3000-808	16	13	autoantibodies	autoantibody	NOUN
dentistry3000-808	16	14	,	,	PUNCT
dentistry3000-808	16	15	such	such	ADJ
dentistry3000-808	16	16	as	as	ADP
dentistry3000-808	16	17	anticitrullinated	anticitrullinate	VERB
dentistry3000-808	16	18	protein	protein	NOUN
dentistry3000-808	16	19	antibodies	antibody	NOUN
dentistry3000-808	16	20	(	(	PUNCT
dentistry3000-808	16	21	acpa	acpa	NOUN
dentistry3000-808	16	22	)	)	PUNCT
dentistry3000-808	16	23	,	,	PUNCT
dentistry3000-808	16	24	which	which	PRON
dentistry3000-808	16	25	activate	activate	VERB
dentistry3000-808	16	26	immune	immune	ADJ
dentistry3000-808	16	27	responses	response	NOUN
dentistry3000-808	16	28	that	that	PRON
dentistry3000-808	16	29	exacerbate	exacerbate	VERB
dentistry3000-808	16	30	joint	joint	ADJ
dentistry3000-808	16	31	inflammation	inflammation	NOUN
dentistry3000-808	16	32	.	.	PUNCT
dentistry3000-808	17	1	the	the	DET
dentistry3000-808	17	2	bidirectional	bidirectional	ADJ
dentistry3000-808	17	3	link	link	NOUN
dentistry3000-808	17	4	between	between	ADP
dentistry3000-808	17	5	periodontal	periodontal	ADJ
dentistry3000-808	17	6	disease	disease	NOUN
dentistry3000-808	17	7	and	and	CCONJ
dentistry3000-808	17	8	ra	ra	NOUN
dentistry3000-808	17	9	,	,	PUNCT
dentistry3000-808	17	10	where	where	SCONJ
dentistry3000-808	17	11	in	in	ADP
dentistry3000-808	17	12	one	one	NUM
dentistry3000-808	17	13	condition	condition	NOUN
dentistry3000-808	17	14	may	may	AUX
dentistry3000-808	17	15	affect	affect	VERB
dentistry3000-808	17	16	the	the	DET
dentistry3000-808	17	17	onset	onset	NOUN
dentistry3000-808	17	18	or	or	CCONJ
dentistry3000-808	17	19	advancement	advancement	NOUN
dentistry3000-808	17	20	of	of	ADP
dentistry3000-808	17	21	the	the	DET
dentistry3000-808	17	22	other	other	ADJ
dentistry3000-808	17	23	,	,	PUNCT
dentistry3000-808	17	24	has	have	AUX
dentistry3000-808	17	25	generated	generate	VERB
dentistry3000-808	17	26	significant	significant	ADJ
dentistry3000-808	17	27	scholarly	scholarly	ADJ
dentistry3000-808	17	28	interest	interest	NOUN
dentistry3000-808	17	29	[	[	X
dentistry3000-808	17	30	3,4	3,4	NUM
dentistry3000-808	17	31	]	]	PUNCT
dentistry3000-808	17	32	.	.	PUNCT
dentistry3000-808	18	1	this	this	DET
dentistry3000-808	18	2	review	review	NOUN
dentistry3000-808	18	3	aims	aim	VERB
dentistry3000-808	18	4	to	to	PART
dentistry3000-808	18	5	examine	examine	VERB
dentistry3000-808	18	6	the	the	DET
dentistry3000-808	18	7	potential	potential	ADJ
dentistry3000-808	18	8	link	link	NOUN
dentistry3000-808	18	9	between	between	ADP
dentistry3000-808	18	10	periodontal	periodontal	ADJ
dentistry3000-808	18	11	infections	infection	NOUN
dentistry3000-808	18	12	and	and	CCONJ
dentistry3000-808	18	13	ra	ra	NOUN
dentistry3000-808	18	14	,	,	PUNCT
dentistry3000-808	18	15	focusing	focus	VERB
dentistry3000-808	18	16	on	on	ADP
dentistry3000-808	18	17	how	how	SCONJ
dentistry3000-808	18	18	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	18	19	,	,	PUNCT
dentistry3000-808	18	20	especially	especially	ADV
dentistry3000-808	18	21	p.	p.	PROPN
dentistry3000-808	18	22	gingivalis	gingivalis	PROPN
dentistry3000-808	18	23	,	,	PUNCT
dentistry3000-808	18	24	may	may	AUX
dentistry3000-808	18	25	contribute	contribute	VERB
dentistry3000-808	18	26	to	to	ADP
dentistry3000-808	18	27	the	the	DET
dentistry3000-808	18	28	initiation	initiation	NOUN
dentistry3000-808	18	29	of	of	ADP
dentistry3000-808	18	30	immune	immune	ADJ
dentistry3000-808	18	31	responses	response	NOUN
dentistry3000-808	18	32	that	that	PRON
dentistry3000-808	18	33	facilitate	facilitate	VERB
dentistry3000-808	18	34	the	the	DET
dentistry3000-808	18	35	onset	onset	NOUN
dentistry3000-808	18	36	and	and	CCONJ
dentistry3000-808	18	37	advancement	advancement	NOUN
dentistry3000-808	18	38	of	of	ADP
dentistry3000-808	18	39	ra	ra	PROPN
dentistry3000-808	18	40	.	.	PUNCT
dentistry3000-808	19	1	materials	material	NOUN
dentistry3000-808	19	2	and	and	CCONJ
dentistry3000-808	19	3	methods	method	NOUN
dentistry3000-808	19	4	for	for	ADP
dentistry3000-808	19	5	this	this	DET
dentistry3000-808	19	6	review	review	NOUN
dentistry3000-808	19	7	,	,	PUNCT
dentistry3000-808	19	8	the	the	DET
dentistry3000-808	19	9	authors	author	NOUN
dentistry3000-808	19	10	executed	execute	VERB
dentistry3000-808	19	11	an	an	DET
dentistry3000-808	19	12	electronic	electronic	ADJ
dentistry3000-808	19	13	search	search	NOUN
dentistry3000-808	19	14	across	across	ADP
dentistry3000-808	19	15	many	many	ADJ
dentistry3000-808	19	16	pertinent	pertinent	ADJ
dentistry3000-808	19	17	scientific	scientific	ADJ
dentistry3000-808	19	18	databases	database	NOUN
dentistry3000-808	19	19	,	,	PUNCT
dentistry3000-808	19	20	including	include	VERB
dentistry3000-808	19	21	scopus	scopus	NOUN
dentistry3000-808	19	22	,	,	PUNCT
dentistry3000-808	19	23	google	google	PROPN
dentistry3000-808	19	24	scholar	scholar	NOUN
dentistry3000-808	19	25	,	,	PUNCT
dentistry3000-808	19	26	pubmed	pubmed	PROPN
dentistry3000-808	19	27	,	,	PUNCT
dentistry3000-808	19	28	mdpi	mdpi	PROPN
dentistry3000-808	19	29	,	,	PUNCT
dentistry3000-808	19	30	and	and	CCONJ
dentistry3000-808	19	31	researchgate	researchgate	NOUN
dentistry3000-808	19	32	.	.	PUNCT
dentistry3000-808	20	1	the	the	DET
dentistry3000-808	20	2	preliminary	preliminary	ADJ
dentistry3000-808	20	3	evaluation	evaluation	NOUN
dentistry3000-808	20	4	encompassed	encompass	VERB
dentistry3000-808	20	5	130	130	NUM
dentistry3000-808	20	6	publications	publication	NOUN
dentistry3000-808	20	7	poten&al	poten&al	PRON
dentistry3000-808	20	8	role	role	NOUN
dentistry3000-808	20	9	of	of	ADP
dentistry3000-808	20	10	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	20	11	in	in	ADP
dentistry3000-808	20	12	rheumatoid	rheumatoid	NOUN
dentistry3000-808	20	13	arthri&s	arthri&s	PROPN
dentistry3000-808	20	14	vol	vol	NOUN
dentistry3000-808	20	15	13	13	NUM
dentistry3000-808	20	16	no	no	DET
dentistry3000-808	20	17	1	1	NUM
dentistry3000-808	20	18	(	(	PUNCT
dentistry3000-808	20	19	2025	2025	NUM
dentistry3000-808	20	20	)	)	PUNCT
dentistry3000-808	20	21	doi	doi	NOUN
dentistry3000-808	20	22	10.5195	10.5195	NUM
dentistry3000-808	20	23	/	/	SYM
dentistry3000-808	20	24	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	20	25	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	20	26	published	publish	VERB
dentistry3000-808	20	27	from	from	ADP
dentistry3000-808	20	28	2020	2020	NUM
dentistry3000-808	20	29	to	to	ADP
dentistry3000-808	20	30	2024	2024	NUM
dentistry3000-808	20	31	that	that	PRON
dentistry3000-808	20	32	featured	feature	VERB
dentistry3000-808	20	33	the	the	DET
dentistry3000-808	20	34	keywords	keyword	NOUN
dentistry3000-808	20	35	“	"	PUNCT
dentistry3000-808	20	36	periodontitis	periodontitis	NOUN
dentistry3000-808	20	37	,	,	PUNCT
dentistry3000-808	20	38	”	"	PUNCT
dentistry3000-808	20	39	“	"	PUNCT
dentistry3000-808	20	40	rheumatoid	rheumatoid	VERB
dentistry3000-808	20	41	arthritis	arthritis	NOUN
dentistry3000-808	20	42	,	,	PUNCT
dentistry3000-808	20	43	”	"	PUNCT
dentistry3000-808	20	44	and	and	CCONJ
dentistry3000-808	20	45	“	"	PUNCT
dentistry3000-808	20	46	porphyromonas	porphyromona	NOUN
dentistry3000-808	20	47	gingivalis	gingivalis	PROPN
dentistry3000-808	20	48	.	.	PUNCT
dentistry3000-808	20	49	”	"	PUNCT
dentistry3000-808	21	1	inclusion	inclusion	NOUN
dentistry3000-808	21	2	criteria	criterion	NOUN
dentistry3000-808	21	3	this	this	DET
dentistry3000-808	21	4	study	study	NOUN
dentistry3000-808	21	5	included	include	VERB
dentistry3000-808	21	6	recent	recent	ADJ
dentistry3000-808	21	7	papers	paper	NOUN
dentistry3000-808	21	8	,	,	PUNCT
dentistry3000-808	21	9	reviews	review	NOUN
dentistry3000-808	21	10	,	,	PUNCT
dentistry3000-808	21	11	and	and	CCONJ
dentistry3000-808	21	12	case	case	NOUN
dentistry3000-808	21	13	-	-	PUNCT
dentistry3000-808	21	14	control	control	NOUN
dentistry3000-808	21	15	studies	study	NOUN
dentistry3000-808	21	16	;	;	PUNCT
dentistry3000-808	21	17	all	all	DET
dentistry3000-808	21	18	articles	article	NOUN
dentistry3000-808	21	19	included	include	VERB
dentistry3000-808	21	20	in	in	ADP
dentistry3000-808	21	21	this	this	DET
dentistry3000-808	21	22	review	review	NOUN
dentistry3000-808	21	23	were	be	AUX
dentistry3000-808	21	24	published	publish	VERB
dentistry3000-808	21	25	in	in	ADP
dentistry3000-808	21	26	english	english	PROPN
dentistry3000-808	21	27	.	.	PUNCT
dentistry3000-808	22	1	exclusion	exclusion	NOUN
dentistry3000-808	22	2	criteria	criterion	NOUN
dentistry3000-808	22	3	articles	article	NOUN
dentistry3000-808	22	4	and	and	CCONJ
dentistry3000-808	22	5	research	research	NOUN
dentistry3000-808	22	6	published	publish	VERB
dentistry3000-808	22	7	prior	prior	ADV
dentistry3000-808	22	8	to	to	ADP
dentistry3000-808	22	9	2020	2020	NUM
dentistry3000-808	22	10	were	be	AUX
dentistry3000-808	22	11	omitted	omit	VERB
dentistry3000-808	22	12	,	,	PUNCT
dentistry3000-808	22	13	as	as	SCONJ
dentistry3000-808	22	14	illustrated	illustrate	VERB
dentistry3000-808	22	15	in	in	ADP
dentistry3000-808	22	16	figure	figure	NOUN
dentistry3000-808	22	17	1	1	NUM
dentistry3000-808	22	18	.	.	PUNCT
dentistry3000-808	23	1	figure	figure	NOUN
dentistry3000-808	23	2	1	1	NUM
dentistry3000-808	23	3	.	.	PUNCT
dentistry3000-808	24	1	progression	progression	NOUN
dentistry3000-808	24	2	of	of	ADP
dentistry3000-808	24	3	the	the	DET
dentistry3000-808	24	4	search	search	NOUN
dentistry3000-808	24	5	and	and	CCONJ
dentistry3000-808	24	6	selection	selection	NOUN
dentistry3000-808	24	7	procedure	procedure	NOUN
dentistry3000-808	24	8	.	.	PUNCT
dentistry3000-808	25	1	periodontitis	periodontitis	NOUN
dentistry3000-808	25	2	periodontitis	periodontitis	NOUN
dentistry3000-808	25	3	is	be	AUX
dentistry3000-808	25	4	a	a	DET
dentistry3000-808	25	5	persistent	persistent	ADJ
dentistry3000-808	25	6	,	,	PUNCT
dentistry3000-808	25	7	damaging	damaging	ADJ
dentistry3000-808	25	8	,	,	PUNCT
dentistry3000-808	25	9	and	and	CCONJ
dentistry3000-808	25	10	permanent	permanent	ADJ
dentistry3000-808	25	11	inflammatory	inflammatory	ADJ
dentistry3000-808	25	12	condition	condition	NOUN
dentistry3000-808	25	13	.	.	PUNCT
dentistry3000-808	26	1	it	it	PRON
dentistry3000-808	26	2	is	be	AUX
dentistry3000-808	26	3	the	the	DET
dentistry3000-808	26	4	predominant	predominant	ADJ
dentistry3000-808	26	5	cause	cause	NOUN
dentistry3000-808	26	6	of	of	ADP
dentistry3000-808	26	7	osteopenia	osteopenia	NOUN
dentistry3000-808	26	8	and	and	CCONJ
dentistry3000-808	26	9	an	an	DET
dentistry3000-808	26	10	infectious	infectious	ADJ
dentistry3000-808	26	11	inflammatory	inflammatory	ADJ
dentistry3000-808	26	12	ailment	ailment	NOUN
dentistry3000-808	26	13	affecting	affect	VERB
dentistry3000-808	26	14	humanity	humanity	NOUN
dentistry3000-808	26	15	[	[	X
dentistry3000-808	26	16	5	5	NUM
dentistry3000-808	26	17	]	]	PUNCT
dentistry3000-808	26	18	.	.	PUNCT
dentistry3000-808	27	1	the	the	DET
dentistry3000-808	27	2	world	world	PROPN
dentistry3000-808	27	3	health	health	PROPN
dentistry3000-808	27	4	organization	organization	NOUN
dentistry3000-808	27	5	classifies	classify	VERB
dentistry3000-808	27	6	pd	pd	PROPN
dentistry3000-808	27	7	as	as	ADP
dentistry3000-808	27	8	unprecedented	unprecedented	ADJ
dentistry3000-808	27	9	global	global	ADJ
dentistry3000-808	27	10	event	event	NOUN
dentistry3000-808	27	11	,	,	PUNCT
dentistry3000-808	27	12	exhibiting	exhibit	VERB
dentistry3000-808	27	13	concerning	concern	VERB
dentistry3000-808	27	14	frequency	frequency	NOUN
dentistry3000-808	27	15	among	among	ADP
dentistry3000-808	27	16	various	various	ADJ
dentistry3000-808	27	17	age	age	NOUN
dentistry3000-808	27	18	demographics	demographic	NOUN
dentistry3000-808	27	19	and	and	CCONJ
dentistry3000-808	27	20	geographic	geographic	ADJ
dentistry3000-808	27	21	areas	area	NOUN
dentistry3000-808	27	22	.	.	PUNCT
dentistry3000-808	28	1	it	it	PRON
dentistry3000-808	28	2	impact	impact	VERB
dentistry3000-808	28	3	around	around	ADV
dentistry3000-808	28	4	19	19	NUM
dentistry3000-808	28	5	%	%	NOUN
dentistry3000-808	28	6	of	of	ADP
dentistry3000-808	28	7	the	the	DET
dentistry3000-808	28	8	world	world	NOUN
dentistry3000-808	28	9	's	's	PART
dentistry3000-808	28	10	residents	resident	NOUN
dentistry3000-808	28	11	,	,	PUNCT
dentistry3000-808	28	12	representing	represent	VERB
dentistry3000-808	28	13	more	more	ADJ
dentistry3000-808	28	14	than	than	ADP
dentistry3000-808	28	15	a	a	DET
dentistry3000-808	28	16	billion	billion	NUM
dentistry3000-808	28	17	instances	instance	NOUN
dentistry3000-808	28	18	.	.	PUNCT
dentistry3000-808	29	1	the	the	DET
dentistry3000-808	29	2	data	datum	NOUN
dentistry3000-808	29	3	concerning	concern	VERB
dentistry3000-808	29	4	european	european	PROPN
dentistry3000-808	29	5	nations	nation	NOUN
dentistry3000-808	29	6	reveals	reveal	VERB
dentistry3000-808	29	7	that	that	SCONJ
dentistry3000-808	29	8	over	over	ADP
dentistry3000-808	29	9	50	50	NUM
dentistry3000-808	29	10	%	%	NOUN
dentistry3000-808	29	11	of	of	ADP
dentistry3000-808	29	12	the	the	DET
dentistry3000-808	29	13	population	population	NOUN
dentistry3000-808	29	14	may	may	AUX
dentistry3000-808	29	15	experience	experience	VERB
dentistry3000-808	29	16	some	some	DET
dentistry3000-808	29	17	variant	variant	NOUN
dentistry3000-808	29	18	of	of	ADP
dentistry3000-808	29	19	pd	pd	PROPN
dentistry3000-808	29	20	,	,	PUNCT
dentistry3000-808	29	21	with	with	ADP
dentistry3000-808	29	22	over	over	ADP
dentistry3000-808	29	23	10	10	NUM
dentistry3000-808	29	24	%	%	NOUN
dentistry3000-808	29	25	afflicted	afflict	VERB
dentistry3000-808	29	26	by	by	ADP
dentistry3000-808	29	27	its	its	PRON
dentistry3000-808	29	28	severe	severe	ADJ
dentistry3000-808	29	29	manifestation	manifestation	NOUN
dentistry3000-808	29	30	.	.	PUNCT
dentistry3000-808	30	1	incidence	incidence	NOUN
dentistry3000-808	30	2	increases	increase	VERB
dentistry3000-808	30	3	up	up	ADV
dentistry3000-808	30	4	to	to	ADP
dentistry3000-808	30	5	70–85	70–85	NUM
dentistry3000-808	30	6	%	%	NOUN
dentistry3000-808	30	7	among	among	ADP
dentistry3000-808	30	8	individuals	individual	NOUN
dentistry3000-808	30	9	of	of	ADP
dentistry3000-808	30	10	60–65	60–65	NUM
dentistry3000-808	30	11	years	year	NOUN
dentistry3000-808	30	12	old	old	ADJ
dentistry3000-808	30	13	[	[	X
dentistry3000-808	30	14	6	6	NUM
dentistry3000-808	30	15	]	]	PUNCT
dentistry3000-808	30	16	.	.	PUNCT
dentistry3000-808	31	1	from	from	ADP
dentistry3000-808	31	2	1990	1990	NUM
dentistry3000-808	31	3	to	to	ADP
dentistry3000-808	31	4	2019	2019	NUM
dentistry3000-808	31	5	,	,	PUNCT
dentistry3000-808	31	6	pd	pd	PROPN
dentistry3000-808	31	7	prevalence	prevalence	NOUN
dentistry3000-808	31	8	rate	rate	NOUN
dentistry3000-808	31	9	rose	rise	VERB
dentistry3000-808	31	10	globally	globally	ADV
dentistry3000-808	31	11	by	by	ADP
dentistry3000-808	31	12	8.44	8.44	NUM
dentistry3000-808	31	13	%	%	NOUN
dentistry3000-808	31	14	[	[	X
dentistry3000-808	31	15	7,8	7,8	NUM
dentistry3000-808	31	16	]	]	PUNCT
dentistry3000-808	31	17	.	.	PUNCT
dentistry3000-808	32	1	the	the	DET
dentistry3000-808	32	2	worldwide	worldwide	ADJ
dentistry3000-808	32	3	load	load	NOUN
dentistry3000-808	32	4	of	of	ADP
dentistry3000-808	32	5	pd	pd	PROPN
dentistry3000-808	32	6	is	be	AUX
dentistry3000-808	32	7	considerable	considerable	ADJ
dentistry3000-808	32	8	and	and	CCONJ
dentistry3000-808	32	9	has	have	AUX
dentistry3000-808	32	10	markedly	markedly	ADV
dentistry3000-808	32	11	escalated	escalate	VERB
dentistry3000-808	32	12	throughout	throughout	ADP
dentistry3000-808	32	13	the	the	DET
dentistry3000-808	32	14	last	last	ADJ
dentistry3000-808	32	15	three	three	NUM
dentistry3000-808	32	16	decades	decade	NOUN
dentistry3000-808	32	17	,	,	PUNCT
dentistry3000-808	32	18	posing	pose	VERB
dentistry3000-808	32	19	a	a	DET
dentistry3000-808	32	20	huge	huge	ADJ
dentistry3000-808	32	21	public	public	ADJ
dentistry3000-808	32	22	health	health	NOUN
dentistry3000-808	32	23	concern	concern	NOUN
dentistry3000-808	32	24	and	and	CCONJ
dentistry3000-808	32	25	necessitating	necessitate	VERB
dentistry3000-808	32	26	the	the	DET
dentistry3000-808	32	27	pursuit	pursuit	NOUN
dentistry3000-808	32	28	of	of	ADP
dentistry3000-808	32	29	novel	novel	ADJ
dentistry3000-808	32	30	therapeutic	therapeutic	ADJ
dentistry3000-808	32	31	interventions	intervention	NOUN
dentistry3000-808	33	1	[	[	X
dentistry3000-808	33	2	6	6	NUM
dentistry3000-808	33	3	]	]	PUNCT
dentistry3000-808	33	4	.	.	PUNCT
dentistry3000-808	34	1	pathogenesis	pathogenesis	NOUN
dentistry3000-808	34	2	of	of	ADP
dentistry3000-808	34	3	periodontitis	periodontitis	NOUN
dentistry3000-808	34	4	the	the	DET
dentistry3000-808	34	5	pathogenesis	pathogenesis	NOUN
dentistry3000-808	34	6	of	of	ADP
dentistry3000-808	34	7	periodontal	periodontal	ADJ
dentistry3000-808	34	8	disease	disease	NOUN
dentistry3000-808	34	9	is	be	AUX
dentistry3000-808	34	10	defined	define	VERB
dentistry3000-808	34	11	by	by	ADP
dentistry3000-808	34	12	the	the	DET
dentistry3000-808	34	13	interplay	interplay	NOUN
dentistry3000-808	34	14	between	between	ADP
dentistry3000-808	34	15	bacterial	bacterial	ADJ
dentistry3000-808	34	16	plaque	plaque	NOUN
dentistry3000-808	34	17	accumulation	accumulation	NOUN
dentistry3000-808	34	18	and	and	CCONJ
dentistry3000-808	34	19	inflammatory	inflammatory	ADJ
dentistry3000-808	34	20	responses	response	NOUN
dentistry3000-808	34	21	in	in	ADP
dentistry3000-808	34	22	the	the	DET
dentistry3000-808	34	23	gingiva	gingiva	NOUN
dentistry3000-808	35	1	[	[	X
dentistry3000-808	35	2	9	9	NUM
dentistry3000-808	35	3	]	]	PUNCT
dentistry3000-808	35	4	.	.	PUNCT
dentistry3000-808	36	1	this	this	DET
dentistry3000-808	36	2	connection	connection	NOUN
dentistry3000-808	36	3	activates	activate	VERB
dentistry3000-808	36	4	fundamental	fundamental	ADJ
dentistry3000-808	36	5	molecular	molecular	ADJ
dentistry3000-808	36	6	routes	route	NOUN
dentistry3000-808	36	7	which	which	PRON
dentistry3000-808	36	8	ultimately	ultimately	ADV
dentistry3000-808	36	9	result	result	VERB
dentistry3000-808	36	10	in	in	ADP
dentistry3000-808	36	11	the	the	DET
dentistry3000-808	36	12	activation	activation	NOUN
dentistry3000-808	36	13	of	of	ADP
dentistry3000-808	36	14	host	host	NOUN
dentistry3000-808	36	15	-	-	PUNCT
dentistry3000-808	36	16	derived	derive	VERB
dentistry3000-808	36	17	proteases	protease	NOUN
dentistry3000-808	36	18	.	.	PUNCT
dentistry3000-808	37	1	this	this	PRON
dentistry3000-808	37	2	leads	lead	VERB
dentistry3000-808	37	3	to	to	ADP
dentistry3000-808	37	4	periodontal	periodontal	ADJ
dentistry3000-808	37	5	ligaments	ligament	NOUN
dentistry3000-808	37	6	marginal	marginal	ADJ
dentistry3000-808	37	7	fibers	fiber	NOUN
dentistry3000-808	37	8	degradation	degradation	NOUN
dentistry3000-808	37	9	,	,	PUNCT
dentistry3000-808	37	10	junctional	junctional	ADJ
dentistry3000-808	37	11	epithelium	epithelium	NOUN
dentistry3000-808	37	12	displacement	displacement	NOUN
dentistry3000-808	37	13	,	,	PUNCT
dentistry3000-808	37	14	and	and	CCONJ
dentistry3000-808	37	15	subsequent	subsequent	ADJ
dentistry3000-808	37	16	bacterial	bacterial	ADJ
dentistry3000-808	37	17	biofilm	biofilm	NOUN
dentistry3000-808	37	18	proliferation	proliferation	NOUN
dentistry3000-808	37	19	along	along	ADP
dentistry3000-808	37	20	the	the	DET
dentistry3000-808	37	21	root	root	NOUN
dentistry3000-808	37	22	surface	surface	NOUN
dentistry3000-808	37	23	apically	apically	ADV
dentistry3000-808	37	24	[	[	X
dentistry3000-808	37	25	10,11	10,11	NOUN
dentistry3000-808	37	26	]	]	PUNCT
dentistry3000-808	37	27	.	.	PUNCT
dentistry3000-808	38	1	the	the	DET
dentistry3000-808	38	2	microbiology	microbiology	NOUN
dentistry3000-808	38	3	of	of	ADP
dentistry3000-808	38	4	pd	pd	PROPN
dentistry3000-808	38	5	is	be	AUX
dentistry3000-808	38	6	intricate	intricate	ADJ
dentistry3000-808	38	7	,	,	PUNCT
dentistry3000-808	38	8	primarily	primarily	ADV
dentistry3000-808	38	9	characterized	characterize	VERB
dentistry3000-808	38	10	by	by	ADP
dentistry3000-808	38	11	a	a	DET
dentistry3000-808	38	12	transition	transition	NOUN
dentistry3000-808	38	13	in	in	ADP
dentistry3000-808	38	14	the	the	DET
dentistry3000-808	38	15	microbial	microbial	ADJ
dentistry3000-808	38	16	population	population	NOUN
dentistry3000-808	38	17	from	from	ADP
dentistry3000-808	38	18	a	a	DET
dentistry3000-808	38	19	largely	largely	ADV
dentistry3000-808	38	20	grampositive	grampositive	ADJ
dentistry3000-808	38	21	,	,	PUNCT
dentistry3000-808	38	22	aerobic	aerobic	ADJ
dentistry3000-808	38	23	,	,	PUNCT
dentistry3000-808	38	24	healthassociated	healthassociated	ADJ
dentistry3000-808	38	25	biofilm	biofilm	NOUN
dentistry3000-808	38	26	to	to	ADP
dentistry3000-808	38	27	a	a	DET
dentistry3000-808	38	28	predominance	predominance	NOUN
dentistry3000-808	38	29	of	of	ADP
dentistry3000-808	38	30	gram	gram	NOUN
dentistry3000-808	38	31	-	-	PUNCT
dentistry3000-808	38	32	negative	negative	ADJ
dentistry3000-808	38	33	anaerobes	anaerobe	NOUN
dentistry3000-808	38	34	.	.	PUNCT
dentistry3000-808	39	1	fundamental	fundamental	ADJ
dentistry3000-808	39	2	molecular	molecular	ADJ
dentistry3000-808	39	3	investigations	investigation	NOUN
dentistry3000-808	39	4	have	have	AUX
dentistry3000-808	39	5	found	find	VERB
dentistry3000-808	39	6	complexes	complex	NOUN
dentistry3000-808	39	7	of	of	ADP
dentistry3000-808	39	8	various	various	ADJ
dentistry3000-808	39	9	bacterial	bacterial	ADJ
dentistry3000-808	39	10	species	specie	NOUN
dentistry3000-808	39	11	linked	link	VERB
dentistry3000-808	39	12	to	to	ADP
dentistry3000-808	39	13	severe	severe	ADJ
dentistry3000-808	39	14	chronic	chronic	ADJ
dentistry3000-808	39	15	periodontitis	periodontitis	NOUN
dentistry3000-808	39	16	,	,	PUNCT
dentistry3000-808	39	17	specifically	specifically	ADV
dentistry3000-808	39	18	p.	p.	PROPN
dentistry3000-808	39	19	gingivalis	gingivalis	PROPN
dentistry3000-808	39	20	,	,	PUNCT
dentistry3000-808	39	21	tanerella	tanerella	NOUN
dentistry3000-808	39	22	forsythia	forsythia	NOUN
dentistry3000-808	39	23	,	,	PUNCT
dentistry3000-808	39	24	and	and	CCONJ
dentistry3000-808	39	25	treponema	treponema	VERB
dentistry3000-808	39	26	denticola	denticola	NOUN
dentistry3000-808	40	1	[	[	X
dentistry3000-808	40	2	12	12	NUM
dentistry3000-808	40	3	]	]	PUNCT
dentistry3000-808	40	4	.	.	PUNCT
dentistry3000-808	41	1	a	a	DET
dentistry3000-808	41	2	recent	recent	ADJ
dentistry3000-808	41	3	study	study	NOUN
dentistry3000-808	41	4	shown	show	VERB
dentistry3000-808	41	5	that	that	SCONJ
dentistry3000-808	41	6	microbial	microbial	ADJ
dentistry3000-808	41	7	populations	population	NOUN
dentistry3000-808	41	8	associated	associate	VERB
dentistry3000-808	41	9	with	with	ADP
dentistry3000-808	41	10	various	various	ADJ
dentistry3000-808	41	11	periodontal	periodontal	ADJ
dentistry3000-808	41	12	conditions	condition	NOUN
dentistry3000-808	41	13	altered	alter	VERB
dentistry3000-808	41	14	in	in	ADP
dentistry3000-808	41	15	an	an	DET
dentistry3000-808	41	16	asynchronous	asynchronous	ADJ
dentistry3000-808	41	17	manner	manner	NOUN
dentistry3000-808	41	18	during	during	ADP
dentistry3000-808	41	19	the	the	DET
dentistry3000-808	41	20	reconstruction	reconstruction	NOUN
dentistry3000-808	41	21	of	of	ADP
dentistry3000-808	41	22	biofilms	biofilm	NOUN
dentistry3000-808	41	23	following	follow	VERB
dentistry3000-808	41	24	its	its	PRON
dentistry3000-808	41	25	initial	initial	ADJ
dentistry3000-808	41	26	elimination	elimination	NOUN
dentistry3000-808	41	27	using	use	VERB
dentistry3000-808	41	28	supragingival	supragingival	NOUN
dentistry3000-808	41	29	cleaning	cleaning	NOUN
dentistry3000-808	41	30	.	.	PUNCT
dentistry3000-808	42	1	research	research	NOUN
dentistry3000-808	42	2	indicates	indicate	VERB
dentistry3000-808	42	3	that	that	SCONJ
dentistry3000-808	42	4	bacteria	bacteria	NOUN
dentistry3000-808	42	5	like	like	ADP
dentistry3000-808	42	6	abiotrophia	abiotrophia	NOUN
dentistry3000-808	42	7	spp	spp	NOUN
dentistry3000-808	42	8	.	.	PUNCT
dentistry3000-808	43	1	and	and	CCONJ
dentistry3000-808	43	2	capnocytophaga	capnocytophaga	PROPN
dentistry3000-808	43	3	spp	spp	PROPN
dentistry3000-808	43	4	.	.	PUNCT
dentistry3000-808	44	1	may	may	AUX
dentistry3000-808	44	2	significantly	significantly	ADV
dentistry3000-808	44	3	influence	influence	VERB
dentistry3000-808	44	4	the	the	DET
dentistry3000-808	44	5	formation	formation	NOUN
dentistry3000-808	44	6	of	of	ADP
dentistry3000-808	44	7	plaque	plaque	NOUN
dentistry3000-808	44	8	biofilms	biofilm	NOUN
dentistry3000-808	44	9	[	[	X
dentistry3000-808	44	10	13	13	NUM
dentistry3000-808	44	11	]	]	PUNCT
dentistry3000-808	44	12	.	.	PUNCT
dentistry3000-808	45	1	while	while	SCONJ
dentistry3000-808	45	2	this	this	DET
dentistry3000-808	45	3	development	development	NOUN
dentistry3000-808	45	4	seems	seem	VERB
dentistry3000-808	45	5	to	to	PART
dentistry3000-808	45	6	have	have	VERB
dentistry3000-808	45	7	a	a	DET
dentistry3000-808	45	8	robust	robust	ADJ
dentistry3000-808	45	9	immunologicalinflammatory	immunologicalinflammatory	ADJ
dentistry3000-808	45	10	foundation	foundation	NOUN
dentistry3000-808	45	11	,	,	PUNCT
dentistry3000-808	45	12	both	both	PRON
dentistry3000-808	45	13	innate	innate	ADJ
dentistry3000-808	45	14	(	(	PUNCT
dentistry3000-808	45	15	sex	sex	NOUN
dentistry3000-808	45	16	and	and	CCONJ
dentistry3000-808	45	17	genetic	genetic	ADJ
dentistry3000-808	45	18	variables	variable	NOUN
dentistry3000-808	45	19	)	)	PUNCT
dentistry3000-808	45	20	and	and	CCONJ
dentistry3000-808	45	21	obtained	obtain	VERB
dentistry3000-808	45	22	(	(	PUNCT
dentistry3000-808	45	23	obesity	obesity	NOUN
dentistry3000-808	45	24	,	,	PUNCT
dentistry3000-808	45	25	stress	stress	NOUN
dentistry3000-808	45	26	,	,	PUNCT
dentistry3000-808	45	27	smoking	smoking	NOUN
dentistry3000-808	45	28	,	,	PUNCT
dentistry3000-808	45	29	concurrent	concurrent	ADJ
dentistry3000-808	45	30	systemic	systemic	ADJ
dentistry3000-808	45	31	disorders	disorder	NOUN
dentistry3000-808	45	32	)	)	PUNCT
dentistry3000-808	45	33	risk	risk	NOUN
dentistry3000-808	45	34	determinants	determinant	NOUN
dentistry3000-808	45	35	significantly	significantly	ADV
dentistry3000-808	45	36	contribute	contribute	VERB
dentistry3000-808	45	37	[	[	X
dentistry3000-808	45	38	14	14	NUM
dentistry3000-808	45	39	]	]	SYM
dentistry3000-808	45	40	.	.	PUNCT
dentistry3000-808	46	1	soft	soft	ADJ
dentistry3000-808	46	2	and	and	CCONJ
dentistry3000-808	46	3	hard	hard	ADJ
dentistry3000-808	46	4	tissues	tissue	NOUN
dentistry3000-808	46	5	around	around	ADP
dentistry3000-808	46	6	the	the	DET
dentistry3000-808	46	7	teeth	tooth	NOUN
dentistry3000-808	46	8	experience	experience	NOUN
dentistry3000-808	46	9	escalating	escalate	VERB
dentistry3000-808	46	10	damage	damage	NOUN
dentistry3000-808	46	11	from	from	ADP
dentistry3000-808	46	12	advancing	advance	VERB
dentistry3000-808	46	13	inflammation	inflammation	NOUN
dentistry3000-808	46	14	due	due	ADJ
dentistry3000-808	46	15	poten&al	poten&al	PROPN
dentistry3000-808	46	16	role	role	NOUN
dentistry3000-808	46	17	of	of	ADP
dentistry3000-808	46	18	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	46	19	in	in	ADP
dentistry3000-808	46	20	rheumatoid	rheumatoid	NOUN
dentistry3000-808	46	21	arthri&s	arthri&s	PROPN
dentistry3000-808	46	22	vol	vol	NOUN
dentistry3000-808	46	23	13	13	NUM
dentistry3000-808	46	24	no	no	DET
dentistry3000-808	46	25	1	1	NUM
dentistry3000-808	46	26	(	(	PUNCT
dentistry3000-808	46	27	2025	2025	NUM
dentistry3000-808	46	28	)	)	PUNCT
dentistry3000-808	46	29	doi	doi	NOUN
dentistry3000-808	46	30	10.5195	10.5195	NUM
dentistry3000-808	46	31	/	/	SYM
dentistry3000-808	46	32	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	46	33	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	46	34	to	to	ADP
dentistry3000-808	46	35	both	both	CCONJ
dentistry3000-808	46	36	the	the	DET
dentistry3000-808	46	37	direct	direct	ADJ
dentistry3000-808	46	38	,	,	PUNCT
dentistry3000-808	46	39	deleterious	deleterious	ADJ
dentistry3000-808	46	40	health	health	NOUN
dentistry3000-808	46	41	risks	risk	NOUN
dentistry3000-808	46	42	associated	associate	VERB
dentistry3000-808	46	43	with	with	ADP
dentistry3000-808	46	44	bacterial	bacterial	ADJ
dentistry3000-808	46	45	virulence	virulence	NOUN
dentistry3000-808	46	46	factors	factor	NOUN
dentistry3000-808	46	47	found	find	VERB
dentistry3000-808	46	48	in	in	ADP
dentistry3000-808	46	49	dental	dental	ADJ
dentistry3000-808	46	50	plaque	plaque	NOUN
dentistry3000-808	46	51	and	and	CCONJ
dentistry3000-808	46	52	the	the	DET
dentistry3000-808	46	53	indirect	indirect	ADJ
dentistry3000-808	46	54	consequences	consequence	NOUN
dentistry3000-808	46	55	of	of	ADP
dentistry3000-808	46	56	the	the	DET
dentistry3000-808	46	57	body	body	NOUN
dentistry3000-808	46	58	's	's	PART
dentistry3000-808	46	59	heightened	heighten	VERB
dentistry3000-808	46	60	,	,	PUNCT
dentistry3000-808	46	61	generalized	generalize	VERB
dentistry3000-808	46	62	inflammatory	inflammatory	ADJ
dentistry3000-808	46	63	reaction	reaction	NOUN
dentistry3000-808	46	64	to	to	ADP
dentistry3000-808	46	65	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	46	66	[	[	X
dentistry3000-808	46	67	15	15	NUM
dentistry3000-808	46	68	]	]	PUNCT
dentistry3000-808	46	69	.	.	PUNCT
dentistry3000-808	47	1	inflammation	inflammation	NOUN
dentistry3000-808	47	2	initiates	initiate	VERB
dentistry3000-808	47	3	a	a	DET
dentistry3000-808	47	4	complicated	complicated	ADJ
dentistry3000-808	47	5	interaction	interaction	NOUN
dentistry3000-808	47	6	of	of	ADP
dentistry3000-808	47	7	proinflammatory	proinflammatory	ADJ
dentistry3000-808	47	8	cytokines	cytokine	NOUN
dentistry3000-808	47	9	,	,	PUNCT
dentistry3000-808	47	10	nitric	nitric	ADJ
dentistry3000-808	47	11	oxide	oxide	NOUN
dentistry3000-808	47	12	,	,	PUNCT
dentistry3000-808	47	13	matrix	matrix	NOUN
dentistry3000-808	47	14	metalloproteinases	metalloproteinase	NOUN
dentistry3000-808	47	15	(	(	PUNCT
dentistry3000-808	47	16	mmps	mmp	NOUN
dentistry3000-808	47	17	)	)	PUNCT
dentistry3000-808	47	18	,	,	PUNCT
dentistry3000-808	47	19	prostaglandin	prostaglandin	NOUN
dentistry3000-808	47	20	e2	e2	NOUN
dentistry3000-808	47	21	,	,	PUNCT
dentistry3000-808	47	22	and	and	CCONJ
dentistry3000-808	47	23	various	various	ADJ
dentistry3000-808	47	24	alternative	alternative	ADJ
dentistry3000-808	47	25	inflammatory	inflammatory	ADJ
dentistry3000-808	47	26	mediators	mediator	NOUN
dentistry3000-808	47	27	.	.	PUNCT
dentistry3000-808	48	1	elevated	elevated	ADJ
dentistry3000-808	48	2	levels	level	NOUN
dentistry3000-808	48	3	of	of	ADP
dentistry3000-808	48	4	tumor	tumor	NOUN
dentistry3000-808	48	5	necrosis	necrosis	NOUN
dentistry3000-808	48	6	factor	factor	NOUN
dentistry3000-808	48	7	alpha	alpha	NOUN
dentistry3000-808	48	8	(	(	PUNCT
dentistry3000-808	48	9	tnfα	tnfα	NOUN
dentistry3000-808	48	10	)	)	PUNCT
dentistry3000-808	48	11	,	,	PUNCT
dentistry3000-808	48	12	interleukin-1	interleukin-1	NOUN
dentistry3000-808	48	13	beta	beta	NOUN
dentistry3000-808	48	14	(	(	PUNCT
dentistry3000-808	48	15	il-1β	il-1β	PROPN
dentistry3000-808	48	16	)	)	PUNCT
dentistry3000-808	48	17	,	,	PUNCT
dentistry3000-808	48	18	il-6	il-6	NUM
dentistry3000-808	48	19	,	,	PUNCT
dentistry3000-808	48	20	il-11	il-11	ADV
dentistry3000-808	48	21	,	,	PUNCT
dentistry3000-808	48	22	and	and	CCONJ
dentistry3000-808	48	23	il-17	il-17	X
dentistry3000-808	48	24	facilitate	facilitate	VERB
dentistry3000-808	48	25	the	the	DET
dentistry3000-808	48	26	formation	formation	NOUN
dentistry3000-808	48	27	of	of	ADP
dentistry3000-808	48	28	osteoclasts	osteoclast	NOUN
dentistry3000-808	48	29	through	through	ADP
dentistry3000-808	48	30	boosting	boost	VERB
dentistry3000-808	48	31	nuclear	nuclear	ADJ
dentistry3000-808	48	32	factor	factor	NOUN
dentistry3000-808	48	33	kappa	kappa	PROPN
dentistry3000-808	48	34	-	-	PUNCT
dentistry3000-808	48	35	β	β	X
dentistry3000-808	48	36	ligand	ligand	NOUN
dentistry3000-808	48	37	receptor	receptor	NOUN
dentistry3000-808	48	38	activator	activator	NOUN
dentistry3000-808	48	39	expression	expression	NOUN
dentistry3000-808	48	40	(	(	PUNCT
dentistry3000-808	48	41	rankl	rankl	VERB
dentistry3000-808	48	42	)	)	PUNCT
dentistry3000-808	48	43	and	and	CCONJ
dentistry3000-808	48	44	diminishing	diminish	VERB
dentistry3000-808	48	45	osteoprotegerin	osteoprotegerin	NOUN
dentistry3000-808	48	46	production	production	NOUN
dentistry3000-808	48	47	[	[	X
dentistry3000-808	48	48	11	11	NUM
dentistry3000-808	48	49	]	]	PUNCT
dentistry3000-808	48	50	.	.	PUNCT
dentistry3000-808	49	1	moreover	moreover	ADV
dentistry3000-808	49	2	,	,	PUNCT
dentistry3000-808	49	3	active	active	ADJ
dentistry3000-808	49	4	periodontal	periodontal	ADJ
dentistry3000-808	49	5	lesions	lesion	NOUN
dentistry3000-808	49	6	demonstrate	demonstrate	VERB
dentistry3000-808	49	7	an	an	DET
dentistry3000-808	49	8	overproduction	overproduction	NOUN
dentistry3000-808	49	9	of	of	ADP
dentistry3000-808	49	10	il-17	il-17	NUM
dentistry3000-808	49	11	and	and	CCONJ
dentistry3000-808	49	12	rankl	rankl	VERB
dentistry3000-808	49	13	,	,	PUNCT
dentistry3000-808	49	14	alongside	alongside	ADP
dentistry3000-808	49	15	reduced	reduce	VERB
dentistry3000-808	49	16	concentrations	concentration	NOUN
dentistry3000-808	49	17	of	of	ADP
dentistry3000-808	49	18	antiinflammatory	antiinflammatory	NOUN
dentistry3000-808	49	19	cytokines	cytokine	NOUN
dentistry3000-808	49	20	such	such	ADJ
dentistry3000-808	49	21	as	as	ADP
dentistry3000-808	49	22	il10	il10	PROPN
dentistry3000-808	49	23	and	and	CCONJ
dentistry3000-808	49	24	transforming	transform	VERB
dentistry3000-808	49	25	growth	growth	NOUN
dentistry3000-808	49	26	factor	factor	NOUN
dentistry3000-808	49	27	beta1	beta1	NOUN
dentistry3000-808	49	28	(	(	PUNCT
dentistry3000-808	49	29	tgf	tgf	NOUN
dentistry3000-808	49	30	-	-	PUNCT
dentistry3000-808	49	31	β1	β1	PROPN
dentistry3000-808	49	32	)	)	PUNCT
dentistry3000-808	49	33	,	,	PUNCT
dentistry3000-808	49	34	indicating	indicate	VERB
dentistry3000-808	49	35	an	an	DET
dentistry3000-808	49	36	aberrant	aberrant	ADJ
dentistry3000-808	49	37	immunological	immunological	ADJ
dentistry3000-808	49	38	reaction	reaction	NOUN
dentistry3000-808	49	39	.	.	PUNCT
dentistry3000-808	50	1	this	this	DET
dentistry3000-808	50	2	disruption	disruption	NOUN
dentistry3000-808	50	3	in	in	ADP
dentistry3000-808	50	4	the	the	DET
dentistry3000-808	50	5	metabolism	metabolism	NOUN
dentistry3000-808	50	6	of	of	ADP
dentistry3000-808	50	7	bone	bone	NOUN
dentistry3000-808	50	8	not	not	PART
dentistry3000-808	50	9	solely	solely	ADV
dentistry3000-808	50	10	incline	incline	VERB
dentistry3000-808	50	11	patients	patient	NOUN
dentistry3000-808	50	12	to	to	ADP
dentistry3000-808	50	13	periodontal	periodontal	ADJ
dentistry3000-808	50	14	disease	disease	NOUN
dentistry3000-808	50	15	but	but	CCONJ
dentistry3000-808	50	16	also	also	ADV
dentistry3000-808	50	17	suggests	suggest	VERB
dentistry3000-808	50	18	it	it	PRON
dentistry3000-808	50	19	in	in	ADP
dentistry3000-808	50	20	the	the	DET
dentistry3000-808	50	21	capacity	capacity	NOUN
dentistry3000-808	50	22	of	of	ADP
dentistry3000-808	50	23	possible	possible	ADJ
dentistry3000-808	50	24	risk	risk	NOUN
dentistry3000-808	50	25	determinant	determinant	ADJ
dentistry3000-808	50	26	for	for	ADP
dentistry3000-808	50	27	conditions	condition	NOUN
dentistry3000-808	50	28	like	like	ADP
dentistry3000-808	50	29	rheumatoid	rheumatoid	NOUN
dentistry3000-808	50	30	arthritis	arthritis	NOUN
dentistry3000-808	50	31	,	,	PUNCT
dentistry3000-808	50	32	however	however	ADV
dentistry3000-808	50	33	,	,	PUNCT
dentistry3000-808	50	34	agreement	agreement	NOUN
dentistry3000-808	50	35	is	be	AUX
dentistry3000-808	50	36	still	still	ADV
dentistry3000-808	50	37	hard	hard	ADJ
dentistry3000-808	50	38	to	to	PART
dentistry3000-808	50	39	grasp	grasp	VERB
dentistry3000-808	50	40	[	[	X
dentistry3000-808	50	41	11,16	11,16	NUM
dentistry3000-808	50	42	]	]	PUNCT
dentistry3000-808	50	43	.	.	PUNCT
dentistry3000-808	51	1	the	the	DET
dentistry3000-808	51	2	keystone	keystone	PROPN
dentistry3000-808	51	3	periodontal	periodontal	PROPN
dentistry3000-808	51	4	pathogen	pathogen	NOUN
dentistry3000-808	51	5	(	(	PUNCT
dentistry3000-808	51	6	porphyromonas	porphyromona	NOUN
dentistry3000-808	51	7	gingivalis	gingivalis	PROPN
dentistry3000-808	51	8	)	)	PUNCT
dentistry3000-808	51	9	the	the	DET
dentistry3000-808	51	10	rod	rod	NOUN
dentistry3000-808	51	11	-	-	PUNCT
dentistry3000-808	51	12	shaped	shape	VERB
dentistry3000-808	51	13	,	,	PUNCT
dentistry3000-808	51	14	gram	gram	NOUN
dentistry3000-808	51	15	-	-	PUNCT
dentistry3000-808	51	16	negative	negative	ADJ
dentistry3000-808	51	17	,	,	PUNCT
dentistry3000-808	51	18	anaerobic	anaerobic	ADJ
dentistry3000-808	51	19	bacteria	bacteria	NOUN
dentistry3000-808	51	20	known	know	VERB
dentistry3000-808	51	21	as	as	ADP
dentistry3000-808	51	22	p.	p.	PROPN
dentistry3000-808	51	23	gingivalis	gingivalis	PROPN
dentistry3000-808	51	24	was	be	AUX
dentistry3000-808	51	25	identified	identify	VERB
dentistry3000-808	51	26	in	in	ADP
dentistry3000-808	51	27	85.75	85.75	NUM
dentistry3000-808	51	28	%	%	NOUN
dentistry3000-808	51	29	of	of	ADP
dentistry3000-808	51	30	subgingival	subgingival	ADJ
dentistry3000-808	51	31	plaque	plaque	NOUN
dentistry3000-808	51	32	in	in	ADP
dentistry3000-808	51	33	individuals	individual	NOUN
dentistry3000-808	51	34	with	with	ADP
dentistry3000-808	51	35	persistent	persistent	ADJ
dentistry3000-808	51	36	periodontal	periodontal	ADJ
dentistry3000-808	51	37	disease	disease	NOUN
dentistry3000-808	51	38	[	[	X
dentistry3000-808	51	39	17	17	NUM
dentistry3000-808	51	40	]	]	PUNCT
dentistry3000-808	51	41	.	.	PUNCT
dentistry3000-808	52	1	the	the	DET
dentistry3000-808	52	2	virulence	virulence	NOUN
dentistry3000-808	52	3	components	component	NOUN
dentistry3000-808	52	4	of	of	ADP
dentistry3000-808	52	5	p.	p.	PROPN
dentistry3000-808	52	6	gingivalis	gingivalis	PROPN
dentistry3000-808	52	7	include	include	VERB
dentistry3000-808	52	8	fimbriae	fimbria	NOUN
dentistry3000-808	52	9	,	,	PUNCT
dentistry3000-808	52	10	haemolysin	haemolysin	NOUN
dentistry3000-808	52	11	,	,	PUNCT
dentistry3000-808	52	12	hemagglutinins	hemagglutinin	NOUN
dentistry3000-808	52	13	,	,	PUNCT
dentistry3000-808	52	14	a	a	DET
dentistry3000-808	52	15	capsule	capsule	NOUN
dentistry3000-808	52	16	,	,	PUNCT
dentistry3000-808	52	17	outer	outer	ADJ
dentistry3000-808	52	18	membrane	membrane	NOUN
dentistry3000-808	52	19	vesicles	vesicle	NOUN
dentistry3000-808	52	20	,	,	PUNCT
dentistry3000-808	52	21	lipopolysaccharides	lipopolysaccharide	NOUN
dentistry3000-808	52	22	,	,	PUNCT
dentistry3000-808	52	23	and	and	CCONJ
dentistry3000-808	52	24	gingipains	gingipain	VERB
dentistry3000-808	52	25	[	[	X
dentistry3000-808	52	26	18	18	NUM
dentistry3000-808	52	27	]	]	PUNCT
dentistry3000-808	52	28	.	.	PUNCT
dentistry3000-808	53	1	the	the	DET
dentistry3000-808	53	2	prevalence	prevalence	NOUN
dentistry3000-808	53	3	of	of	ADP
dentistry3000-808	53	4	p.	p.	PROPN
dentistry3000-808	53	5	gingivalis	gingivalis	PROPN
dentistry3000-808	53	6	correlates	correlate	VERB
dentistry3000-808	53	7	with	with	ADP
dentistry3000-808	53	8	the	the	DET
dentistry3000-808	53	9	severity	severity	NOUN
dentistry3000-808	53	10	of	of	ADP
dentistry3000-808	53	11	periodontal	periodontal	ADJ
dentistry3000-808	53	12	disease	disease	NOUN
dentistry3000-808	53	13	and	and	CCONJ
dentistry3000-808	53	14	has	have	AUX
dentistry3000-808	53	15	been	be	AUX
dentistry3000-808	53	16	recognized	recognize	VERB
dentistry3000-808	53	17	by	by	ADP
dentistry3000-808	53	18	researchers	researcher	NOUN
dentistry3000-808	53	19	as	as	ADP
dentistry3000-808	53	20	a	a	DET
dentistry3000-808	53	21	primary	primary	ADJ
dentistry3000-808	53	22	causal	causal	ADJ
dentistry3000-808	53	23	element	element	NOUN
dentistry3000-808	53	24	in	in	ADP
dentistry3000-808	53	25	the	the	DET
dentistry3000-808	53	26	pd	pd	PROPN
dentistry3000-808	53	27	progression	progression	NOUN
dentistry3000-808	53	28	.	.	PUNCT
dentistry3000-808	54	1	the	the	DET
dentistry3000-808	54	2	keystone	keystone	PROPN
dentistry3000-808	54	3	pathogen	pathogen	PROPN
dentistry3000-808	54	4	idea	idea	NOUN
dentistry3000-808	54	5	suggests	suggest	VERB
dentistry3000-808	54	6	that	that	SCONJ
dentistry3000-808	54	7	p.	p.	PROPN
dentistry3000-808	54	8	gingivalis	gingivalis	PROPN
dentistry3000-808	54	9	,	,	PUNCT
dentistry3000-808	54	10	even	even	ADV
dentistry3000-808	54	11	in	in	ADP
dentistry3000-808	54	12	minimal	minimal	ADJ
dentistry3000-808	54	13	quantities	quantity	NOUN
dentistry3000-808	54	14	,	,	PUNCT
dentistry3000-808	54	15	might	might	AUX
dentistry3000-808	54	16	trigger	trigger	VERB
dentistry3000-808	54	17	chronic	chronic	ADJ
dentistry3000-808	54	18	periodontal	periodontal	ADJ
dentistry3000-808	54	19	disease	disease	NOUN
dentistry3000-808	54	20	by	by	ADP
dentistry3000-808	54	21	altering	alter	VERB
dentistry3000-808	54	22	the	the	DET
dentistry3000-808	54	23	commensal	commensal	ADJ
dentistry3000-808	54	24	bacterial	bacterial	ADJ
dentistry3000-808	54	25	community	community	NOUN
dentistry3000-808	54	26	,	,	PUNCT
dentistry3000-808	54	27	resulting	result	VERB
dentistry3000-808	54	28	in	in	ADP
dentistry3000-808	54	29	dysbiosis	dysbiosis	NOUN
dentistry3000-808	54	30	and	and	CCONJ
dentistry3000-808	54	31	subsequent	subsequent	ADJ
dentistry3000-808	54	32	disease	disease	NOUN
dentistry3000-808	54	33	[	[	X
dentistry3000-808	54	34	19	19	NUM
dentistry3000-808	54	35	]	]	PUNCT
dentistry3000-808	54	36	.	.	PUNCT
dentistry3000-808	55	1	role	role	NOUN
dentistry3000-808	55	2	of	of	ADP
dentistry3000-808	55	3	porphyromonas	porphyromona	NOUN
dentistry3000-808	55	4	gingivalis	gingivalis	VERB
dentistry3000-808	55	5	in	in	ADP
dentistry3000-808	55	6	periodontal	periodontal	ADJ
dentistry3000-808	55	7	disease	disease	NOUN
dentistry3000-808	55	8	in	in	ADP
dentistry3000-808	55	9	vivo	vivo	ADJ
dentistry3000-808	55	10	investigations	investigation	NOUN
dentistry3000-808	55	11	in	in	ADP
dentistry3000-808	55	12	mice	mouse	NOUN
dentistry3000-808	55	13	have	have	AUX
dentistry3000-808	55	14	demonstrated	demonstrate	VERB
dentistry3000-808	55	15	that	that	PRON
dentistry3000-808	55	16	contagion	contagion	NOUN
dentistry3000-808	55	17	with	with	ADP
dentistry3000-808	55	18	p.	p.	PROPN
dentistry3000-808	55	19	gingivalis	gingivalis	PROPN
dentistry3000-808	55	20	induces	induce	VERB
dentistry3000-808	55	21	osteoclastic	osteoclastic	ADJ
dentistry3000-808	55	22	activity	activity	NOUN
dentistry3000-808	55	23	[	[	X
dentistry3000-808	55	24	20	20	NUM
dentistry3000-808	55	25	]	]	PUNCT
dentistry3000-808	55	26	.	.	PUNCT
dentistry3000-808	56	1	p.	p.	NOUN
dentistry3000-808	56	2	gingivalis	gingivalis	PROPN
dentistry3000-808	56	3	attaches	attach	VERB
dentistry3000-808	56	4	to	to	PART
dentistry3000-808	56	5	and	and	CCONJ
dentistry3000-808	56	6	infiltrates	infiltrate	VERB
dentistry3000-808	56	7	the	the	DET
dentistry3000-808	56	8	epithelial	epithelial	ADJ
dentistry3000-808	56	9	layers	layer	NOUN
dentistry3000-808	56	10	,	,	PUNCT
dentistry3000-808	56	11	proliferates	proliferate	VERB
dentistry3000-808	56	12	and	and	CCONJ
dentistry3000-808	56	13	induces	induce	VERB
dentistry3000-808	56	14	periodontal	periodontal	ADJ
dentistry3000-808	56	15	disease	disease	NOUN
dentistry3000-808	56	16	.	.	PUNCT
dentistry3000-808	57	1	although	although	SCONJ
dentistry3000-808	57	2	the	the	DET
dentistry3000-808	57	3	epithelium	epithelium	NOUN
dentistry3000-808	57	4	serves	serve	VERB
dentistry3000-808	57	5	as	as	ADP
dentistry3000-808	57	6	the	the	DET
dentistry3000-808	57	7	primary	primary	ADJ
dentistry3000-808	57	8	obstacle	obstacle	NOUN
dentistry3000-808	57	9	in	in	ADP
dentistry3000-808	57	10	opposition	opposition	NOUN
dentistry3000-808	57	11	to	to	ADP
dentistry3000-808	57	12	numerous	numerous	ADJ
dentistry3000-808	57	13	diseases	disease	NOUN
dentistry3000-808	57	14	,	,	PUNCT
dentistry3000-808	57	15	including	include	VERB
dentistry3000-808	57	16	periodontal	periodontal	ADJ
dentistry3000-808	57	17	microbiome	microbiome	NOUN
dentistry3000-808	57	18	,	,	PUNCT
dentistry3000-808	57	19	p.	p.	NOUN
dentistry3000-808	57	20	gingivalis	gingivalis	PROPN
dentistry3000-808	57	21	infiltrates	infiltrate	VERB
dentistry3000-808	57	22	gingival	gingival	NOUN
dentistry3000-808	57	23	epithelium	epithelium	NOUN
dentistry3000-808	57	24	along	along	ADP
dentistry3000-808	57	25	with	with	ADP
dentistry3000-808	57	26	the	the	DET
dentistry3000-808	57	27	fundamental	fundamental	ADJ
dentistry3000-808	57	28	connective	connective	ADJ
dentistry3000-808	57	29	tissues	tissue	NOUN
dentistry3000-808	57	30	[	[	X
dentistry3000-808	57	31	23,24	23,24	X
dentistry3000-808	57	32	]	]	PUNCT
dentistry3000-808	57	33	.	.	PUNCT
dentistry3000-808	58	1	it	it	PRON
dentistry3000-808	58	2	plays	play	VERB
dentistry3000-808	58	3	a	a	DET
dentistry3000-808	58	4	substantial	substantial	ADJ
dentistry3000-808	58	5	role	role	NOUN
dentistry3000-808	58	6	in	in	ADP
dentistry3000-808	58	7	the	the	DET
dentistry3000-808	58	8	etiology	etiology	NOUN
dentistry3000-808	58	9	of	of	ADP
dentistry3000-808	58	10	aggressive	aggressive	ADJ
dentistry3000-808	58	11	pd	pd	NOUN
dentistry3000-808	58	12	by	by	ADP
dentistry3000-808	58	13	eliciting	elicit	VERB
dentistry3000-808	58	14	elevated	elevated	ADJ
dentistry3000-808	58	15	degrees	degree	NOUN
dentistry3000-808	58	16	of	of	ADP
dentistry3000-808	58	17	proinflammatory	proinflammatory	ADJ
dentistry3000-808	58	18	cytokines	cytokine	NOUN
dentistry3000-808	58	19	[	[	X
dentistry3000-808	58	20	25	25	NUM
dentistry3000-808	58	21	]	]	PUNCT
dentistry3000-808	58	22	.	.	PUNCT
dentistry3000-808	59	1	serotypes	serotype	NOUN
dentistry3000-808	59	2	k1	k1	PROPN
dentistry3000-808	59	3	and	and	CCONJ
dentistry3000-808	59	4	k2	k2	PROPN
dentistry3000-808	59	5	are	be	AUX
dentistry3000-808	59	6	linked	link	VERB
dentistry3000-808	59	7	to	to	ADP
dentistry3000-808	59	8	elevated	elevated	ADJ
dentistry3000-808	59	9	expression	expression	NOUN
dentistry3000-808	59	10	of	of	ADP
dentistry3000-808	59	11	receptor	receptor	NOUN
dentistry3000-808	59	12	activator	activator	NOUN
dentistry3000-808	59	13	rankl	rankl	VERB
dentistry3000-808	59	14	.	.	PUNCT
dentistry3000-808	60	1	this	this	DET
dentistry3000-808	60	2	element	element	NOUN
dentistry3000-808	60	3	influences	influence	VERB
dentistry3000-808	60	4	the	the	DET
dentistry3000-808	60	5	generation	generation	NOUN
dentistry3000-808	60	6	and	and	CCONJ
dentistry3000-808	60	7	development	development	NOUN
dentistry3000-808	60	8	of	of	ADP
dentistry3000-808	60	9	osteoclasts	osteoclast	NOUN
dentistry3000-808	60	10	and	and	CCONJ
dentistry3000-808	60	11	triggers	trigger	VERB
dentistry3000-808	60	12	a	a	DET
dentistry3000-808	60	13	robust	robust	ADJ
dentistry3000-808	60	14	t	t	NOUN
dentistry3000-808	60	15	helper1	helper1	X
dentistry3000-808	60	16	(	(	PUNCT
dentistry3000-808	60	17	th1	th1	NOUN
dentistry3000-808	60	18	)	)	PUNCT
dentistry3000-808	60	19	and	and	CCONJ
dentistry3000-808	60	20	th17	th17	PROPN
dentistry3000-808	60	21	inflammatory	inflammatory	ADJ
dentistry3000-808	60	22	reaction	reaction	NOUN
dentistry3000-808	60	23	,	,	PUNCT
dentistry3000-808	60	24	leading	lead	VERB
dentistry3000-808	60	25	to	to	ADP
dentistry3000-808	60	26	increased	increase	VERB
dentistry3000-808	60	27	breakdown	breakdown	NOUN
dentistry3000-808	60	28	of	of	ADP
dentistry3000-808	60	29	alveolar	alveolar	ADJ
dentistry3000-808	60	30	osseous	osseous	ADJ
dentistry3000-808	60	31	tissues	tissue	NOUN
dentistry3000-808	60	32	and	and	CCONJ
dentistry3000-808	60	33	enhanced	enhance	VERB
dentistry3000-808	60	34	destruction	destruction	NOUN
dentistry3000-808	60	35	of	of	ADP
dentistry3000-808	60	36	periodontal	periodontal	ADJ
dentistry3000-808	60	37	tissue	tissue	NOUN
dentistry3000-808	61	1	[	[	X
dentistry3000-808	61	2	26	26	NUM
dentistry3000-808	61	3	]	]	PUNCT
dentistry3000-808	61	4	.	.	PUNCT
dentistry3000-808	62	1	the	the	DET
dentistry3000-808	62	2	complement	complement	NOUN
dentistry3000-808	62	3	system	system	NOUN
dentistry3000-808	62	4	safeguards	safeguard	VERB
dentistry3000-808	62	5	the	the	DET
dentistry3000-808	62	6	host	host	NOUN
dentistry3000-808	62	7	against	against	ADP
dentistry3000-808	62	8	microbial	microbial	ADJ
dentistry3000-808	62	9	infections	infection	NOUN
dentistry3000-808	62	10	via	via	ADP
dentistry3000-808	62	11	opsonization	opsonization	NOUN
dentistry3000-808	62	12	,	,	PUNCT
dentistry3000-808	62	13	chemotaxis	chemotaxis	ADJ
dentistry3000-808	62	14	,	,	PUNCT
dentistry3000-808	62	15	and	and	CCONJ
dentistry3000-808	62	16	infected	infected	ADJ
dentistry3000-808	62	17	cells	cell	NOUN
dentistry3000-808	62	18	destruction	destruction	NOUN
dentistry3000-808	63	1	[	[	X
dentistry3000-808	63	2	22	22	NUM
dentistry3000-808	63	3	]	]	PUNCT
dentistry3000-808	63	4	.	.	PUNCT
dentistry3000-808	64	1	p.	p.	NOUN
dentistry3000-808	64	2	gingivalis	gingivalis	PROPN
dentistry3000-808	64	3	exhibits	exhibit	VERB
dentistry3000-808	64	4	resistance	resistance	NOUN
dentistry3000-808	64	5	to	to	ADP
dentistry3000-808	64	6	the	the	DET
dentistry3000-808	64	7	complement	complement	NOUN
dentistry3000-808	64	8	system	system	NOUN
dentistry3000-808	64	9	via	via	ADP
dentistry3000-808	64	10	the	the	DET
dentistry3000-808	64	11	activity	activity	NOUN
dentistry3000-808	64	12	of	of	ADP
dentistry3000-808	64	13	its	its	PRON
dentistry3000-808	64	14	enzymes	enzyme	NOUN
dentistry3000-808	64	15	or	or	CCONJ
dentistry3000-808	64	16	by	by	ADP
dentistry3000-808	64	17	surface	surface	NOUN
dentistry3000-808	64	18	chemicals	chemical	NOUN
dentistry3000-808	64	19	that	that	PRON
dentistry3000-808	64	20	enable	enable	VERB
dentistry3000-808	64	21	adaptation	adaptation	NOUN
dentistry3000-808	64	22	to	to	ADP
dentistry3000-808	64	23	the	the	DET
dentistry3000-808	64	24	regulatory	regulatory	ADJ
dentistry3000-808	64	25	proteins	protein	NOUN
dentistry3000-808	64	26	of	of	ADP
dentistry3000-808	64	27	the	the	DET
dentistry3000-808	64	28	host	host	NOUN
dentistry3000-808	64	29	's	's	PART
dentistry3000-808	64	30	complement	complement	NOUN
dentistry3000-808	64	31	.	.	PUNCT
dentistry3000-808	65	1	p.	p.	NOUN
dentistry3000-808	65	2	gingivalis	gingivalis	PROPN
dentistry3000-808	65	3	inhibits	inhibit	VERB
dentistry3000-808	65	4	the	the	DET
dentistry3000-808	65	5	cascade	cascade	NOUN
dentistry3000-808	65	6	process	process	NOUN
dentistry3000-808	65	7	of	of	ADP
dentistry3000-808	65	8	complement	complement	NOUN
dentistry3000-808	65	9	component	component	NOUN
dentistry3000-808	65	10	5	5	NUM
dentistry3000-808	65	11	convertase	convertase	NOUN
dentistry3000-808	65	12	production	production	NOUN
dentistry3000-808	65	13	within	within	ADP
dentistry3000-808	65	14	the	the	DET
dentistry3000-808	65	15	complement	complement	NOUN
dentistry3000-808	65	16	system	system	NOUN
dentistry3000-808	65	17	[	[	X
dentistry3000-808	65	18	22,27	22,27	NOUN
dentistry3000-808	65	19	]	]	PUNCT
dentistry3000-808	65	20	.	.	PUNCT
dentistry3000-808	66	1	poten&al	poten&al	PROPN
dentistry3000-808	66	2	role	role	NOUN
dentistry3000-808	66	3	of	of	ADP
dentistry3000-808	66	4	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	66	5	in	in	ADP
dentistry3000-808	66	6	rheumatoid	rheumatoid	NOUN
dentistry3000-808	66	7	arthri&s	arthri&s	PROPN
dentistry3000-808	66	8	vol	vol	NOUN
dentistry3000-808	66	9	13	13	NUM
dentistry3000-808	66	10	no	no	DET
dentistry3000-808	66	11	1	1	NUM
dentistry3000-808	66	12	(	(	PUNCT
dentistry3000-808	66	13	2025	2025	NUM
dentistry3000-808	66	14	)	)	PUNCT
dentistry3000-808	66	15	doi	doi	NOUN
dentistry3000-808	66	16	10.5195	10.5195	NUM
dentistry3000-808	66	17	/	/	SYM
dentistry3000-808	66	18	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	66	19	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	66	20	moreover	moreover	ADV
dentistry3000-808	66	21	,	,	PUNCT
dentistry3000-808	66	22	complement	complement	NOUN
dentistry3000-808	66	23	component	component	NOUN
dentistry3000-808	66	24	3	3	NUM
dentistry3000-808	66	25	interacts	interact	VERB
dentistry3000-808	66	26	with	with	ADP
dentistry3000-808	66	27	p.	p.	NOUN
dentistry3000-808	66	28	gingivalis	gingivalis	PROPN
dentistry3000-808	66	29	fimbriae	fimbriae	NOUN
dentistry3000-808	66	30	,	,	PUNCT
dentistry3000-808	66	31	facilitating	facilitate	VERB
dentistry3000-808	66	32	the	the	DET
dentistry3000-808	66	33	internalization	internalization	NOUN
dentistry3000-808	66	34	of	of	ADP
dentistry3000-808	66	35	the	the	DET
dentistry3000-808	66	36	bacteria	bacteria	NOUN
dentistry3000-808	66	37	by	by	ADP
dentistry3000-808	66	38	macrophages	macrophage	NOUN
dentistry3000-808	66	39	.	.	PUNCT
dentistry3000-808	67	1	p.	p.	NOUN
dentistry3000-808	67	2	gingivalis	gingivalis	PROPN
dentistry3000-808	67	3	utilizes	utilize	VERB
dentistry3000-808	67	4	the	the	DET
dentistry3000-808	67	5	synergy	synergy	NOUN
dentistry3000-808	67	6	and	and	CCONJ
dentistry3000-808	67	7	crosstalk	crosstalk	VERB
dentistry3000-808	67	8	between	between	ADP
dentistry3000-808	67	9	complement	complement	NOUN
dentistry3000-808	67	10	and	and	CCONJ
dentistry3000-808	67	11	toll	toll	NOUN
dentistry3000-808	67	12	-	-	PUNCT
dentistry3000-808	67	13	like	like	ADJ
dentistry3000-808	67	14	receptors	receptor	NOUN
dentistry3000-808	67	15	to	to	PART
dentistry3000-808	67	16	alter	alter	VERB
dentistry3000-808	67	17	host	host	NOUN
dentistry3000-808	67	18	defenses	defense	NOUN
dentistry3000-808	67	19	and	and	CCONJ
dentistry3000-808	67	20	evade	evade	VERB
dentistry3000-808	67	21	elimination	elimination	NOUN
dentistry3000-808	67	22	by	by	ADP
dentistry3000-808	67	23	the	the	DET
dentistry3000-808	67	24	host	host	NOUN
dentistry3000-808	67	25	[	[	X
dentistry3000-808	67	26	19	19	NUM
dentistry3000-808	67	27	]	]	PUNCT
dentistry3000-808	67	28	.	.	PUNCT
dentistry3000-808	68	1	levels	level	NOUN
dentistry3000-808	68	2	of	of	ADP
dentistry3000-808	68	3	complements	complement	NOUN
dentistry3000-808	68	4	proteins	protein	NOUN
dentistry3000-808	68	5	in	in	ADP
dentistry3000-808	68	6	crevicular	crevicular	ADJ
dentistry3000-808	68	7	fluid	fluid	NOUN
dentistry3000-808	68	8	are	be	AUX
dentistry3000-808	68	9	diminished	diminish	VERB
dentistry3000-808	68	10	in	in	ADP
dentistry3000-808	68	11	individuals	individual	NOUN
dentistry3000-808	68	12	with	with	ADP
dentistry3000-808	68	13	periodontal	periodontal	ADJ
dentistry3000-808	68	14	disease	disease	NOUN
dentistry3000-808	68	15	[	[	X
dentistry3000-808	68	16	22,26	22,26	NOUN
dentistry3000-808	68	17	]	]	PUNCT
dentistry3000-808	68	18	.	.	PUNCT
dentistry3000-808	69	1	p.	p.	NOUN
dentistry3000-808	69	2	gingivalis	gingivalis	PROPN
dentistry3000-808	69	3	can	can	AUX
dentistry3000-808	69	4	evade	evade	VERB
dentistry3000-808	69	5	neutrophils	neutrophil	NOUN
dentistry3000-808	69	6	devastation	devastation	NOUN
dentistry3000-808	69	7	through	through	ADP
dentistry3000-808	69	8	diminishing	diminish	VERB
dentistry3000-808	69	9	their	their	PRON
dentistry3000-808	69	10	antibacterial	antibacterial	ADJ
dentistry3000-808	69	11	and	and	CCONJ
dentistry3000-808	69	12	chemotaxis	chemotaxis	ADJ
dentistry3000-808	69	13	efficacy	efficacy	NOUN
dentistry3000-808	69	14	[	[	X
dentistry3000-808	69	15	21,25	21,25	NUM
dentistry3000-808	69	16	]	]	PUNCT
dentistry3000-808	69	17	.	.	PUNCT
dentistry3000-808	70	1	the	the	DET
dentistry3000-808	70	2	survival	survival	NOUN
dentistry3000-808	70	3	mechanisms	mechanism	NOUN
dentistry3000-808	70	4	of	of	ADP
dentistry3000-808	70	5	p.	p.	NOUN
dentistry3000-808	70	6	gingivalis	gingivalis	PROPN
dentistry3000-808	70	7	lead	lead	VERB
dentistry3000-808	70	8	to	to	ADP
dentistry3000-808	70	9	a	a	DET
dentistry3000-808	70	10	remodeled	remodel	VERB
dentistry3000-808	70	11	microbiota	microbiota	NOUN
dentistry3000-808	70	12	,	,	PUNCT
dentistry3000-808	70	13	resulting	result	VERB
dentistry3000-808	70	14	in	in	ADP
dentistry3000-808	70	15	a	a	DET
dentistry3000-808	70	16	dysbiotic	dysbiotic	ADJ
dentistry3000-808	70	17	condition	condition	NOUN
dentistry3000-808	70	18	that	that	PRON
dentistry3000-808	70	19	induces	induce	VERB
dentistry3000-808	70	20	inflammatory	inflammatory	ADJ
dentistry3000-808	70	21	diseases	disease	NOUN
dentistry3000-808	70	22	such	such	ADJ
dentistry3000-808	70	23	as	as	ADP
dentistry3000-808	70	24	periodontal	periodontal	ADJ
dentistry3000-808	70	25	disease	disease	NOUN
dentistry3000-808	70	26	[	[	X
dentistry3000-808	70	27	19	19	NUM
dentistry3000-808	70	28	]	]	PUNCT
dentistry3000-808	70	29	.	.	PUNCT
dentistry3000-808	71	1	rheumatoid	rheumatoid	VERB
dentistry3000-808	71	2	arthritis	arthritis	NOUN
dentistry3000-808	71	3	rheumatoid	rheumatoid	NOUN
dentistry3000-808	71	4	arthritis	arthritis	NOUN
dentistry3000-808	71	5	is	be	AUX
dentistry3000-808	71	6	an	an	DET
dentistry3000-808	71	7	autoimmune	autoimmune	ADJ
dentistry3000-808	71	8	,	,	PUNCT
dentistry3000-808	71	9	systemic	systemic	ADJ
dentistry3000-808	71	10	inflammatory	inflammatory	ADJ
dentistry3000-808	71	11	disorder	disorder	NOUN
dentistry3000-808	71	12	that	that	SCONJ
dentistry3000-808	71	13	impacts	impact	VERB
dentistry3000-808	71	14	roughly	roughly	ADV
dentistry3000-808	71	15	1	1	NUM
dentistry3000-808	71	16	%	%	NOUN
dentistry3000-808	71	17	of	of	ADP
dentistry3000-808	71	18	the	the	DET
dentistry3000-808	71	19	population	population	NOUN
dentistry3000-808	71	20	.	.	PUNCT
dentistry3000-808	72	1	it	it	PRON
dentistry3000-808	72	2	is	be	AUX
dentistry3000-808	72	3	marked	mark	VERB
dentistry3000-808	72	4	by	by	ADP
dentistry3000-808	72	5	persistent	persistent	ADJ
dentistry3000-808	72	6	joint	joint	ADJ
dentistry3000-808	72	7	inflammation	inflammation	NOUN
dentistry3000-808	72	8	,	,	PUNCT
dentistry3000-808	72	9	destruction	destruction	NOUN
dentistry3000-808	72	10	of	of	ADP
dentistry3000-808	72	11	bone	bone	NOUN
dentistry3000-808	72	12	and	and	CCONJ
dentistry3000-808	72	13	cartilage	cartilage	NOUN
dentistry3000-808	72	14	,	,	PUNCT
dentistry3000-808	72	15	and	and	CCONJ
dentistry3000-808	72	16	systemic	systemic	ADJ
dentistry3000-808	72	17	extra	extra	ADJ
dentistry3000-808	72	18	-	-	ADJ
dentistry3000-808	72	19	articular	articular	ADJ
dentistry3000-808	72	20	manifestations	manifestation	NOUN
dentistry3000-808	72	21	not	not	PART
dentistry3000-808	72	22	directly	directly	ADV
dentistry3000-808	72	23	associated	associate	VERB
dentistry3000-808	72	24	with	with	ADP
dentistry3000-808	72	25	the	the	DET
dentistry3000-808	72	26	musculoskeletal	musculoskeletal	ADJ
dentistry3000-808	72	27	system	system	NOUN
dentistry3000-808	72	28	[	[	X
dentistry3000-808	72	29	27	27	NUM
dentistry3000-808	72	30	]	]	PUNCT
dentistry3000-808	72	31	,	,	PUNCT
dentistry3000-808	72	32	which	which	PRON
dentistry3000-808	72	33	occur	occur	VERB
dentistry3000-808	72	34	in	in	ADP
dentistry3000-808	72	35	a	a	DET
dentistry3000-808	72	36	significant	significant	ADJ
dentistry3000-808	72	37	proportion	proportion	NOUN
dentistry3000-808	72	38	of	of	ADP
dentistry3000-808	72	39	patients	patient	NOUN
dentistry3000-808	72	40	,	,	PUNCT
dentistry3000-808	72	41	resulting	result	VERB
dentistry3000-808	72	42	in	in	ADP
dentistry3000-808	72	43	poorer	poor	ADJ
dentistry3000-808	72	44	disease	disease	NOUN
dentistry3000-808	72	45	outcomes	outcome	NOUN
dentistry3000-808	72	46	[	[	X
dentistry3000-808	72	47	28	28	NUM
dentistry3000-808	72	48	]	]	PUNCT
dentistry3000-808	72	49	.	.	PUNCT
dentistry3000-808	73	1	ra	ra	PROPN
dentistry3000-808	73	2	patients	patient	NOUN
dentistry3000-808	73	3	frequently	frequently	ADV
dentistry3000-808	73	4	display	display	VERB
dentistry3000-808	73	5	diverse	diverse	ADJ
dentistry3000-808	73	6	oral	oral	ADJ
dentistry3000-808	73	7	manifestations	manifestation	NOUN
dentistry3000-808	73	8	,	,	PUNCT
dentistry3000-808	73	9	notably	notably	ADV
dentistry3000-808	73	10	the	the	DET
dentistry3000-808	73	11	recognized	recognize	VERB
dentistry3000-808	73	12	association	association	NOUN
dentistry3000-808	73	13	with	with	ADP
dentistry3000-808	73	14	sjogren	sjogren	PROPN
dentistry3000-808	73	15	’s	’s	PART
dentistry3000-808	73	16	syndrome	syndrome	NOUN
dentistry3000-808	73	17	,	,	PUNCT
dentistry3000-808	73	18	resulting	result	VERB
dentistry3000-808	73	19	in	in	ADP
dentistry3000-808	73	20	symptoms	symptom	NOUN
dentistry3000-808	73	21	such	such	ADJ
dentistry3000-808	73	22	as	as	ADP
dentistry3000-808	73	23	xerostomia	xerostomia	NOUN
dentistry3000-808	73	24	.	.	PUNCT
dentistry3000-808	74	1	additional	additional	ADJ
dentistry3000-808	74	2	oral	oral	ADJ
dentistry3000-808	74	3	concerns	concern	NOUN
dentistry3000-808	74	4	encompass	encompass	VERB
dentistry3000-808	74	5	temporomandibular	temporomandibular	ADJ
dentistry3000-808	74	6	joint	joint	ADJ
dentistry3000-808	74	7	abnormalities	abnormality	NOUN
dentistry3000-808	74	8	,	,	PUNCT
dentistry3000-808	74	9	methotrexateinduced	methotrexateinduce	VERB
dentistry3000-808	74	10	ulcers	ulcer	NOUN
dentistry3000-808	74	11	,	,	PUNCT
dentistry3000-808	74	12	and	and	CCONJ
dentistry3000-808	74	13	an	an	DET
dentistry3000-808	74	14	increasing	increase	VERB
dentistry3000-808	74	15	emphasis	emphasis	NOUN
dentistry3000-808	74	16	on	on	ADP
dentistry3000-808	74	17	periodontal	periodontal	ADJ
dentistry3000-808	74	18	disease	disease	NOUN
dentistry3000-808	74	19	[	[	X
dentistry3000-808	74	20	29	29	NUM
dentistry3000-808	74	21	]	]	PUNCT
dentistry3000-808	74	22	.	.	PUNCT
dentistry3000-808	75	1	pathogenesis	pathogenesis	NOUN
dentistry3000-808	75	2	of	of	ADP
dentistry3000-808	75	3	rheumatoid	rheumatoid	VERB
dentistry3000-808	75	4	arthritis	arthritis	NOUN
dentistry3000-808	75	5	vulnerability	vulnerability	NOUN
dentistry3000-808	75	6	and	and	CCONJ
dentistry3000-808	75	7	initiation	initiation	NOUN
dentistry3000-808	75	8	of	of	ADP
dentistry3000-808	75	9	ra	ra	PROPN
dentistry3000-808	75	10	rise	rise	VERB
dentistry3000-808	75	11	from	from	ADP
dentistry3000-808	75	12	ambient	ambient	ADJ
dentistry3000-808	75	13	and	and	CCONJ
dentistry3000-808	75	14	hereditary	hereditary	ADJ
dentistry3000-808	75	15	variables	variable	NOUN
dentistry3000-808	75	16	.	.	PUNCT
dentistry3000-808	76	1	the	the	DET
dentistry3000-808	76	2	most	most	ADV
dentistry3000-808	76	3	often	often	ADV
dentistry3000-808	76	4	used	use	VERB
dentistry3000-808	76	5	autoantibodies	autoantibody	NOUN
dentistry3000-808	76	6	in	in	ADP
dentistry3000-808	76	7	clinical	clinical	ADJ
dentistry3000-808	76	8	practice	practice	NOUN
dentistry3000-808	76	9	are	be	AUX
dentistry3000-808	76	10	acpas	acpas	ADJ
dentistry3000-808	76	11	,	,	PUNCT
dentistry3000-808	76	12	which	which	PRON
dentistry3000-808	76	13	may	may	AUX
dentistry3000-808	76	14	be	be	AUX
dentistry3000-808	76	15	detected	detect	VERB
dentistry3000-808	76	16	in	in	ADP
dentistry3000-808	76	17	ra	ra	PROPN
dentistry3000-808	76	18	patients	patient	NOUN
dentistry3000-808	76	19	years	year	NOUN
dentistry3000-808	76	20	prior	prior	ADV
dentistry3000-808	76	21	to	to	ADP
dentistry3000-808	76	22	symptom	symptom	NOUN
dentistry3000-808	76	23	manifestation	manifestation	PROPN
dentistry3000-808	76	24	.	.	PUNCT
dentistry3000-808	77	1	peptidyl	peptidyl	NOUN
dentistry3000-808	77	2	arginine	arginine	NOUN
dentistry3000-808	77	3	deiminase	deiminase	NOUN
dentistry3000-808	77	4	(	(	PUNCT
dentistry3000-808	77	5	padi	padi	PROPN
dentistry3000-808	77	6	)	)	PUNCT
dentistry3000-808	77	7	facilitates	facilitate	VERB
dentistry3000-808	77	8	the	the	DET
dentistry3000-808	77	9	post	post	ADJ
dentistry3000-808	77	10	-	-	ADJ
dentistry3000-808	77	11	translational	translational	ADJ
dentistry3000-808	77	12	modification	modification	NOUN
dentistry3000-808	77	13	that	that	PRON
dentistry3000-808	77	14	transforms	transform	VERB
dentistry3000-808	77	15	arginine	arginine	NOUN
dentistry3000-808	77	16	or	or	CCONJ
dentistry3000-808	77	17	glycine	glycine	NOUN
dentistry3000-808	77	18	residues	residue	NOUN
dentistry3000-808	77	19	in	in	ADP
dentistry3000-808	77	20	normal	normal	ADJ
dentistry3000-808	77	21	proteins	protein	NOUN
dentistry3000-808	77	22	into	into	ADP
dentistry3000-808	77	23	citrulline	citrulline	NOUN
dentistry3000-808	77	24	,	,	PUNCT
dentistry3000-808	77	25	a	a	DET
dentistry3000-808	77	26	significant	significant	ADJ
dentistry3000-808	77	27	factor	factor	NOUN
dentistry3000-808	77	28	contributing	contribute	VERB
dentistry3000-808	77	29	to	to	ADP
dentistry3000-808	77	30	the	the	DET
dentistry3000-808	77	31	abrogation	abrogation	NOUN
dentistry3000-808	77	32	of	of	ADP
dentistry3000-808	77	33	immunological	immunological	ADJ
dentistry3000-808	77	34	tolerance	tolerance	NOUN
dentistry3000-808	77	35	in	in	ADP
dentistry3000-808	77	36	ra	ra	PROPN
dentistry3000-808	77	37	patients	patient	NOUN
dentistry3000-808	77	38	[	[	X
dentistry3000-808	77	39	30	30	NUM
dentistry3000-808	77	40	]	]	PUNCT
dentistry3000-808	77	41	.	.	PUNCT
dentistry3000-808	78	1	non	non	ADJ
dentistry3000-808	78	2	-	-	ADJ
dentistry3000-808	78	3	resolving	resolving	ADJ
dentistry3000-808	78	4	inflammation	inflammation	NOUN
dentistry3000-808	78	5	driven	drive	VERB
dentistry3000-808	78	6	by	by	ADP
dentistry3000-808	78	7	aberrantly	aberrantly	ADV
dentistry3000-808	78	8	activated	activate	VERB
dentistry3000-808	78	9	immune	immune	ADJ
dentistry3000-808	78	10	cells	cell	NOUN
dentistry3000-808	78	11	plays	play	VERB
dentistry3000-808	78	12	a	a	DET
dentistry3000-808	78	13	crucial	crucial	ADJ
dentistry3000-808	78	14	role	role	NOUN
dentistry3000-808	78	15	in	in	ADP
dentistry3000-808	78	16	the	the	DET
dentistry3000-808	78	17	development	development	NOUN
dentistry3000-808	78	18	of	of	ADP
dentistry3000-808	78	19	ra	ra	PROPN
dentistry3000-808	78	20	.	.	PROPN
dentistry3000-808	78	21	immune	immune	PROPN
dentistry3000-808	78	22	cells	cell	NOUN
dentistry3000-808	78	23	penetrate	penetrate	VERB
dentistry3000-808	78	24	the	the	DET
dentistry3000-808	78	25	synovium	synovium	NOUN
dentistry3000-808	78	26	diffusely	diffusely	NOUN
dentistry3000-808	78	27	;	;	PUNCT
dentistry3000-808	78	28	however	however	ADV
dentistry3000-808	78	29	,	,	PUNCT
dentistry3000-808	78	30	in	in	ADP
dentistry3000-808	78	31	some	some	DET
dentistry3000-808	78	32	instances	instance	NOUN
dentistry3000-808	78	33	,	,	PUNCT
dentistry3000-808	78	34	t	t	NOUN
dentistry3000-808	78	35	cells	cell	NOUN
dentistry3000-808	78	36	and	and	CCONJ
dentistry3000-808	78	37	b	b	NOUN
dentistry3000-808	78	38	cells	cell	NOUN
dentistry3000-808	78	39	form	form	NOUN
dentistry3000-808	78	40	consolidates	consolidate	VERB
dentistry3000-808	78	41	,	,	PUNCT
dentistry3000-808	78	42	with	with	ADP
dentistry3000-808	78	43	or	or	CCONJ
dentistry3000-808	78	44	without	without	ADP
dentistry3000-808	78	45	follicular	follicular	ADJ
dentistry3000-808	78	46	dendritic	dendritic	ADJ
dentistry3000-808	78	47	cells	cell	NOUN
dentistry3000-808	78	48	,	,	PUNCT
dentistry3000-808	78	49	leading	lead	VERB
dentistry3000-808	78	50	to	to	ADP
dentistry3000-808	78	51	the	the	DET
dentistry3000-808	78	52	formation	formation	NOUN
dentistry3000-808	78	53	of	of	ADP
dentistry3000-808	78	54	lymphoid	lymphoid	NOUN
dentistry3000-808	78	55	consolidates	consolidate	VERB
dentistry3000-808	78	56	or	or	CCONJ
dentistry3000-808	78	57	ectopic	ectopic	VERB
dentistry3000-808	78	58	germinal	germinal	ADJ
dentistry3000-808	78	59	centers	center	NOUN
dentistry3000-808	78	60	[	[	X
dentistry3000-808	78	61	31	31	NUM
dentistry3000-808	78	62	]	]	PUNCT
dentistry3000-808	78	63	.	.	PUNCT
dentistry3000-808	79	1	this	this	DET
dentistry3000-808	79	2	process	process	NOUN
dentistry3000-808	79	3	contributes	contribute	VERB
dentistry3000-808	79	4	to	to	ADP
dentistry3000-808	79	5	the	the	DET
dentistry3000-808	79	6	breakdown	breakdown	NOUN
dentistry3000-808	79	7	of	of	ADP
dentistry3000-808	79	8	self	self	NOUN
dentistry3000-808	79	9	-	-	PUNCT
dentistry3000-808	79	10	tolerance	tolerance	NOUN
dentistry3000-808	79	11	and	and	CCONJ
dentistry3000-808	79	12	accelerates	accelerate	VERB
dentistry3000-808	79	13	the	the	DET
dentistry3000-808	79	14	pathogenesis	pathogenesis	NOUN
dentistry3000-808	79	15	of	of	ADP
dentistry3000-808	79	16	ra	ra	PROPN
dentistry3000-808	79	17	.	.	PUNCT
dentistry3000-808	80	1	in	in	ADP
dentistry3000-808	80	2	ra	ra	PROPN
dentistry3000-808	80	3	,	,	PUNCT
dentistry3000-808	80	4	the	the	DET
dentistry3000-808	80	5	majority	majority	NOUN
dentistry3000-808	80	6	of	of	ADP
dentistry3000-808	80	7	proinflammatory	proinflammatory	ADJ
dentistry3000-808	80	8	cytokines	cytokine	NOUN
dentistry3000-808	80	9	originate	originate	VERB
dentistry3000-808	80	10	from	from	ADP
dentistry3000-808	80	11	macrophages	macrophage	NOUN
dentistry3000-808	80	12	and	and	CCONJ
dentistry3000-808	80	13	fibroblast	fibroblast	ADJ
dentistry3000-808	80	14	-	-	PUNCT
dentistry3000-808	80	15	like	like	ADJ
dentistry3000-808	80	16	synoviocytes	synoviocyte	NOUN
dentistry3000-808	80	17	,	,	PUNCT
dentistry3000-808	80	18	including	include	VERB
dentistry3000-808	80	19	il-1	il-1	ADP
dentistry3000-808	80	20	,	,	PUNCT
dentistry3000-808	80	21	il-6	il-6	NUM
dentistry3000-808	80	22	and	and	CCONJ
dentistry3000-808	80	23	tnf	tnf	PROPN
dentistry3000-808	80	24	-	-	PUNCT
dentistry3000-808	80	25	α	α	PROPN
dentistry3000-808	80	26	.	.	PUNCT
dentistry3000-808	81	1	tnf	tnf	PROPN
dentistry3000-808	81	2	-	-	PUNCT
dentistry3000-808	81	3	α	α	PROPN
dentistry3000-808	81	4	,	,	PUNCT
dentistry3000-808	81	5	a	a	DET
dentistry3000-808	81	6	key	key	ADJ
dentistry3000-808	81	7	proinflammatory	proinflammatory	ADJ
dentistry3000-808	81	8	cytokine	cytokine	NOUN
dentistry3000-808	81	9	in	in	ADP
dentistry3000-808	81	10	ra	ra	PROPN
dentistry3000-808	81	11	,	,	PUNCT
dentistry3000-808	81	12	enhances	enhance	VERB
dentistry3000-808	81	13	inflammation	inflammation	NOUN
dentistry3000-808	81	14	by	by	ADP
dentistry3000-808	81	15	activating	activate	VERB
dentistry3000-808	81	16	the	the	DET
dentistry3000-808	81	17	nf	nf	ADJ
dentistry3000-808	81	18	-	-	PUNCT
dentistry3000-808	81	19	κb	κb	NOUN
dentistry3000-808	81	20	pathway	pathway	NOUN
dentistry3000-808	81	21	,	,	PUNCT
dentistry3000-808	81	22	which	which	PRON
dentistry3000-808	81	23	promotes	promote	VERB
dentistry3000-808	81	24	osteoclast	osteoclast	ADJ
dentistry3000-808	81	25	formation	formation	NOUN
dentistry3000-808	81	26	[	[	X
dentistry3000-808	81	27	31,32	31,32	NUM
dentistry3000-808	81	28	]	]	X
dentistry3000-808	81	29	.	.	PUNCT
dentistry3000-808	81	30	il-1	il-1	PUNCT
dentistry3000-808	82	1	similarly	similarly	ADV
dentistry3000-808	82	2	causes	cause	VERB
dentistry3000-808	82	3	fast	fast	ADJ
dentistry3000-808	82	4	and	and	CCONJ
dentistry3000-808	82	5	powerful	powerful	ADJ
dentistry3000-808	82	6	inflammatory	inflammatory	ADJ
dentistry3000-808	82	7	reactions	reaction	NOUN
dentistry3000-808	82	8	,	,	PUNCT
dentistry3000-808	82	9	primarily	primarily	ADV
dentistry3000-808	82	10	generated	generate	VERB
dentistry3000-808	82	11	by	by	ADP
dentistry3000-808	82	12	macrophages	macrophage	NOUN
dentistry3000-808	82	13	in	in	ADP
dentistry3000-808	82	14	ra	ra	PROPN
dentistry3000-808	82	15	.	.	PUNCT
dentistry3000-808	82	16	il-1	il-1	PUNCT
dentistry3000-808	83	1	may	may	AUX
dentistry3000-808	83	2	additionally	additionally	ADV
dentistry3000-808	83	3	enhance	enhance	VERB
dentistry3000-808	83	4	il-6	il-6	PRON
dentistry3000-808	83	5	,	,	PUNCT
dentistry3000-808	83	6	il-8	il-8	NOUN
dentistry3000-808	83	7	,	,	PUNCT
dentistry3000-808	83	8	granulocyte	granulocyte	ADJ
dentistry3000-808	83	9	-	-	PUNCT
dentistry3000-808	83	10	macrophage	macrophage	ADJ
dentistry3000-808	83	11	colony	colony	NOUN
dentistry3000-808	83	12	-	-	PUNCT
dentistry3000-808	83	13	stimulating	stimulate	VERB
dentistry3000-808	83	14	factor	factor	NOUN
dentistry3000-808	83	15	,	,	PUNCT
dentistry3000-808	83	16	collagenase	collagenase	NOUN
dentistry3000-808	83	17	,	,	PUNCT
dentistry3000-808	83	18	and	and	CCONJ
dentistry3000-808	83	19	prostaglandins	prostaglandin	VERB
dentistry3000-808	83	20	synthesis	synthesis	NOUN
dentistry3000-808	83	21	[	[	X
dentistry3000-808	83	22	31	31	NUM
dentistry3000-808	83	23	]	]	PUNCT
dentistry3000-808	83	24	.	.	PUNCT
dentistry3000-808	84	1	large	large	ADJ
dentistry3000-808	84	2	quantities	quantity	NOUN
dentistry3000-808	84	3	of	of	ADP
dentistry3000-808	84	4	il-6	il-6	NOUN
dentistry3000-808	84	5	in	in	ADP
dentistry3000-808	84	6	the	the	DET
dentistry3000-808	84	7	synovial	synovial	ADJ
dentistry3000-808	84	8	fluid	fluid	NOUN
dentistry3000-808	84	9	of	of	ADP
dentistry3000-808	84	10	ra	ra	PROPN
dentistry3000-808	84	11	individuals	individual	NOUN
dentistry3000-808	84	12	may	may	AUX
dentistry3000-808	84	13	additionally	additionally	ADV
dentistry3000-808	84	14	transmit	transmit	VERB
dentistry3000-808	84	15	stimuli	stimulus	NOUN
dentistry3000-808	84	16	of	of	ADP
dentistry3000-808	84	17	pathogenic	pathogenic	ADJ
dentistry3000-808	84	18	inflammation	inflammation	NOUN
dentistry3000-808	84	19	in	in	ADP
dentistry3000-808	84	20	rafibroblast	rafibroblast	NOUN
dentistry3000-808	84	21	-	-	PUNCT
dentistry3000-808	84	22	like	like	ADJ
dentistry3000-808	84	23	synoviocytes	synoviocyte	NOUN
dentistry3000-808	84	24	via	via	ADP
dentistry3000-808	84	25	the	the	DET
dentistry3000-808	84	26	janus	janus	PROPN
dentistry3000-808	84	27	kinase	kinase	PROPN
dentistry3000-808	84	28	pathway	pathway	NOUN
dentistry3000-808	85	1	[	[	X
dentistry3000-808	85	2	33	33	NUM
dentistry3000-808	85	3	]	]	PUNCT
dentistry3000-808	85	4	.	.	PUNCT
dentistry3000-808	86	1	the	the	DET
dentistry3000-808	86	2	association	association	NOUN
dentistry3000-808	86	3	between	between	ADP
dentistry3000-808	86	4	rheumatoid	rheumatoid	NOUN
dentistry3000-808	86	5	arthritis	arthritis	NOUN
dentistry3000-808	86	6	and	and	CCONJ
dentistry3000-808	86	7	periodontitis	periodontitis	NOUN
dentistry3000-808	86	8	the	the	DET
dentistry3000-808	86	9	findings	finding	NOUN
dentistry3000-808	86	10	from	from	ADP
dentistry3000-808	86	11	previous	previous	ADJ
dentistry3000-808	86	12	study	study	NOUN
dentistry3000-808	86	13	have	have	AUX
dentistry3000-808	86	14	garnered	garner	VERB
dentistry3000-808	86	15	significant	significant	ADJ
dentistry3000-808	86	16	interest	interest	NOUN
dentistry3000-808	86	17	from	from	ADP
dentistry3000-808	86	18	both	both	CCONJ
dentistry3000-808	86	19	chinese	chinese	ADJ
dentistry3000-808	86	20	and	and	CCONJ
dentistry3000-808	86	21	foreign	foreign	ADJ
dentistry3000-808	86	22	scholars	scholar	NOUN
dentistry3000-808	86	23	regarding	regard	VERB
dentistry3000-808	86	24	the	the	DET
dentistry3000-808	86	25	correlation	correlation	NOUN
dentistry3000-808	86	26	between	between	ADP
dentistry3000-808	86	27	pd	pd	PROPN
dentistry3000-808	86	28	and	and	CCONJ
dentistry3000-808	86	29	ra	ra	PROPN
dentistry3000-808	86	30	.	.	PROPN
dentistry3000-808	86	31	cantley	cantley	PROPN
dentistry3000-808	86	32	et	et	PROPN
dentistry3000-808	86	33	al	al	PROPN
dentistry3000-808	86	34	discovered	discover	VERB
dentistry3000-808	86	35	that	that	SCONJ
dentistry3000-808	86	36	animals	animal	NOUN
dentistry3000-808	86	37	afflicted	afflict	VERB
dentistry3000-808	86	38	with	with	ADP
dentistry3000-808	86	39	both	both	PRON
dentistry3000-808	86	40	pd	pd	PROPN
dentistry3000-808	86	41	and	and	CCONJ
dentistry3000-808	86	42	poten&al	poten&al	PROPN
dentistry3000-808	86	43	role	role	NOUN
dentistry3000-808	86	44	of	of	ADP
dentistry3000-808	86	45	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	86	46	in	in	ADP
dentistry3000-808	86	47	rheumatoid	rheumatoid	NOUN
dentistry3000-808	86	48	arthri&s	arthri&s	PROPN
dentistry3000-808	86	49	vol	vol	NOUN
dentistry3000-808	86	50	13	13	NUM
dentistry3000-808	86	51	no	no	DET
dentistry3000-808	86	52	1	1	NUM
dentistry3000-808	86	53	(	(	PUNCT
dentistry3000-808	86	54	2025	2025	NUM
dentistry3000-808	86	55	)	)	PUNCT
dentistry3000-808	86	56	doi	doi	NOUN
dentistry3000-808	86	57	10.5195	10.5195	NUM
dentistry3000-808	86	58	/	/	SYM
dentistry3000-808	86	59	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	86	60	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	86	61	ra	ra	PROPN
dentistry3000-808	86	62	exhibit	exhibit	VERB
dentistry3000-808	86	63	more	more	ADV
dentistry3000-808	86	64	severe	severe	ADJ
dentistry3000-808	86	65	ra	ra	NOUN
dentistry3000-808	86	66	activity	activity	NOUN
dentistry3000-808	86	67	and	and	CCONJ
dentistry3000-808	86	68	an	an	DET
dentistry3000-808	86	69	earlier	early	ADJ
dentistry3000-808	86	70	commencement	commencement	NOUN
dentistry3000-808	87	1	[	[	X
dentistry3000-808	87	2	34	34	NUM
dentistry3000-808	87	3	]	]	PUNCT
dentistry3000-808	87	4	.	.	PUNCT
dentistry3000-808	88	1	il-1	il-1	PROPN
dentistry3000-808	89	1	and	and	CCONJ
dentistry3000-808	89	2	tnf	tnf	PROPN
dentistry3000-808	89	3	-	-	PUNCT
dentistry3000-808	89	4	α	α	PROPN
dentistry3000-808	89	5	are	be	AUX
dentistry3000-808	89	6	proinflammatory	proinflammatory	ADJ
dentistry3000-808	89	7	cytokines	cytokine	NOUN
dentistry3000-808	89	8	which	which	PRON
dentistry3000-808	89	9	significantly	significantly	ADV
dentistry3000-808	89	10	contribute	contribute	VERB
dentistry3000-808	89	11	to	to	ADP
dentistry3000-808	89	12	the	the	DET
dentistry3000-808	89	13	pathogenesis	pathogenesis	NOUN
dentistry3000-808	89	14	of	of	ADP
dentistry3000-808	89	15	periodontal	periodontal	ADJ
dentistry3000-808	89	16	disease	disease	NOUN
dentistry3000-808	89	17	and	and	CCONJ
dentistry3000-808	89	18	ra	ra	NOUN
dentistry3000-808	89	19	.	.	PUNCT
dentistry3000-808	90	1	they	they	PRON
dentistry3000-808	90	2	prompt	prompt	VERB
dentistry3000-808	90	3	inflammatory	inflammatory	ADJ
dentistry3000-808	90	4	cells	cell	NOUN
dentistry3000-808	90	5	to	to	PART
dentistry3000-808	90	6	infiltrate	infiltrate	VERB
dentistry3000-808	90	7	the	the	DET
dentistry3000-808	90	8	diseased	diseased	ADJ
dentistry3000-808	90	9	area	area	NOUN
dentistry3000-808	90	10	,	,	PUNCT
dentistry3000-808	90	11	resulting	result	VERB
dentistry3000-808	90	12	in	in	ADP
dentistry3000-808	90	13	bone	bone	NOUN
dentistry3000-808	90	14	degradation	degradation	NOUN
dentistry3000-808	90	15	through	through	ADP
dentistry3000-808	90	16	the	the	DET
dentistry3000-808	90	17	inflammatory	inflammatory	ADJ
dentistry3000-808	90	18	mediators	mediator	NOUN
dentistry3000-808	90	19	secretion	secretion	NOUN
dentistry3000-808	90	20	and	and	CCONJ
dentistry3000-808	90	21	cytokines	cytokine	VERB
dentistry3000-808	90	22	activation	activation	NOUN
dentistry3000-808	90	23	,	,	PUNCT
dentistry3000-808	90	24	which	which	PRON
dentistry3000-808	90	25	facilitates	facilitate	VERB
dentistry3000-808	90	26	the	the	DET
dentistry3000-808	90	27	breakdown	breakdown	NOUN
dentistry3000-808	90	28	of	of	ADP
dentistry3000-808	90	29	alveolar	alveolar	ADJ
dentistry3000-808	90	30	osseous	osseous	ADJ
dentistry3000-808	90	31	tissue	tissue	NOUN
dentistry3000-808	90	32	and	and	CCONJ
dentistry3000-808	90	33	collagen	collagen	NOUN
dentistry3000-808	90	34	fibers	fiber	NOUN
dentistry3000-808	90	35	degradation	degradation	NOUN
dentistry3000-808	90	36	in	in	ADP
dentistry3000-808	90	37	periodontal	periodontal	ADJ
dentistry3000-808	90	38	disease	disease	NOUN
dentistry3000-808	90	39	[	[	X
dentistry3000-808	90	40	35	35	NUM
dentistry3000-808	90	41	]	]	PUNCT
dentistry3000-808	90	42	.	.	PUNCT
dentistry3000-808	91	1	recent	recent	ADJ
dentistry3000-808	91	2	data	datum	NOUN
dentistry3000-808	91	3	demonstrates	demonstrate	VERB
dentistry3000-808	91	4	a	a	DET
dentistry3000-808	91	5	substantial	substantial	ADJ
dentistry3000-808	91	6	association	association	NOUN
dentistry3000-808	91	7	between	between	ADP
dentistry3000-808	91	8	susceptibility	susceptibility	NOUN
dentistry3000-808	91	9	to	to	ADP
dentistry3000-808	91	10	ra	ra	PROPN
dentistry3000-808	91	11	and	and	CCONJ
dentistry3000-808	91	12	the	the	DET
dentistry3000-808	91	13	human	human	ADJ
dentistry3000-808	91	14	leukocyte	leukocyte	NOUN
dentistry3000-808	91	15	antigen	antigen	NOUN
dentistry3000-808	91	16	drb1	drb1	NOUN
dentistry3000-808	91	17	(	(	PUNCT
dentistry3000-808	91	18	hla	hla	NOUN
dentistry3000-808	91	19	-	-	PUNCT
dentistry3000-808	91	20	drb1	drb1	NOUN
dentistry3000-808	91	21	)	)	PUNCT
dentistry3000-808	91	22	genetic	genetic	ADJ
dentistry3000-808	91	23	locus	locus	NOUN
dentistry3000-808	91	24	,	,	PUNCT
dentistry3000-808	91	25	due	due	ADP
dentistry3000-808	91	26	to	to	ADP
dentistry3000-808	91	27	the	the	DET
dentistry3000-808	91	28	binding	binding	NOUN
dentistry3000-808	91	29	of	of	ADP
dentistry3000-808	91	30	citrullinated	citrullinate	VERB
dentistry3000-808	91	31	self	self	NOUN
dentistry3000-808	91	32	-	-	PUNCT
dentistry3000-808	91	33	peptides	peptide	NOUN
dentistry3000-808	91	34	to	to	ADP
dentistry3000-808	91	35	hladr	hladr	NOUN
dentistry3000-808	91	36	molecules	molecule	NOUN
dentistry3000-808	91	37	.	.	PUNCT
dentistry3000-808	92	1	p.	p.	NOUN
dentistry3000-808	92	2	gingivalis	gingivalis	PROPN
dentistry3000-808	92	3	,	,	PUNCT
dentistry3000-808	92	4	a	a	DET
dentistry3000-808	92	5	principal	principal	ADJ
dentistry3000-808	92	6	microbiome	microbiome	NOUN
dentistry3000-808	92	7	in	in	ADP
dentistry3000-808	92	8	periodontal	periodontal	ADJ
dentistry3000-808	92	9	disease	disease	NOUN
dentistry3000-808	92	10	and	and	CCONJ
dentistry3000-808	92	11	the	the	DET
dentistry3000-808	92	12	only	only	ADJ
dentistry3000-808	92	13	recognized	recognize	VERB
dentistry3000-808	92	14	human	human	ADJ
dentistry3000-808	92	15	microbiome	microbiome	NOUN
dentistry3000-808	92	16	that	that	PRON
dentistry3000-808	92	17	expresses	express	VERB
dentistry3000-808	92	18	padi	padi	NOUN
dentistry3000-808	92	19	,	,	PUNCT
dentistry3000-808	92	20	is	be	AUX
dentistry3000-808	92	21	pivotal	pivotal	ADJ
dentistry3000-808	92	22	.	.	PUNCT
dentistry3000-808	93	1	this	this	DET
dentistry3000-808	93	2	enzyme	enzyme	NOUN
dentistry3000-808	93	3	generates	generate	VERB
dentistry3000-808	93	4	citrullinated	citrullinate	VERB
dentistry3000-808	93	5	epitopes	epitope	NOUN
dentistry3000-808	93	6	,	,	PUNCT
dentistry3000-808	93	7	which	which	PRON
dentistry3000-808	93	8	are	be	AUX
dentistry3000-808	93	9	recognized	recognize	VERB
dentistry3000-808	93	10	by	by	ADP
dentistry3000-808	93	11	acpa	acpa	PRON
dentistry3000-808	93	12	in	in	ADP
dentistry3000-808	93	13	ra	ra	PROPN
dentistry3000-808	94	1	[	[	X
dentistry3000-808	94	2	36	36	NUM
dentistry3000-808	94	3	]	]	PUNCT
dentistry3000-808	94	4	.	.	PUNCT
dentistry3000-808	95	1	a	a	DET
dentistry3000-808	95	2	prospective	prospective	ADJ
dentistry3000-808	95	3	study	study	NOUN
dentistry3000-808	95	4	revealed	reveal	VERB
dentistry3000-808	95	5	that	that	SCONJ
dentistry3000-808	95	6	persons	person	NOUN
dentistry3000-808	95	7	with	with	ADP
dentistry3000-808	95	8	ra	ra	PROPN
dentistry3000-808	95	9	exhibited	exhibit	VERB
dentistry3000-808	95	10	a	a	DET
dentistry3000-808	95	11	greater	great	ADJ
dentistry3000-808	95	12	prevalence	prevalence	NOUN
dentistry3000-808	95	13	of	of	ADP
dentistry3000-808	95	14	periodontal	periodontal	ADJ
dentistry3000-808	95	15	disease	disease	NOUN
dentistry3000-808	95	16	pd	pd	PROPN
dentistry3000-808	95	17	,	,	PUNCT
dentistry3000-808	95	18	especially	especially	ADV
dentistry3000-808	95	19	in	in	ADP
dentistry3000-808	95	20	the	the	DET
dentistry3000-808	95	21	midst	midst	NOUN
dentistry3000-808	95	22	of	of	ADP
dentistry3000-808	95	23	the	the	DET
dentistry3000-808	95	24	individuals	individual	NOUN
dentistry3000-808	95	25	with	with	ADP
dentistry3000-808	95	26	increased	increase	VERB
dentistry3000-808	95	27	concentrations	concentration	NOUN
dentistry3000-808	95	28	of	of	ADP
dentistry3000-808	95	29	p.	p.	PROPN
dentistry3000-808	95	30	gingivalis	gingivalis	PROPN
dentistry3000-808	95	31	in	in	ADP
dentistry3000-808	95	32	profound	profound	ADJ
dentistry3000-808	95	33	periodontal	periodontal	ADJ
dentistry3000-808	95	34	pockets	pocket	NOUN
dentistry3000-808	95	35	,	,	PUNCT
dentistry3000-808	95	36	in	in	ADP
dentistry3000-808	95	37	comparison	comparison	NOUN
dentistry3000-808	95	38	to	to	ADP
dentistry3000-808	95	39	healthy	healthy	ADJ
dentistry3000-808	95	40	individuals	individual	NOUN
dentistry3000-808	95	41	[	[	X
dentistry3000-808	95	42	37	37	NUM
dentistry3000-808	95	43	]	]	PUNCT
dentistry3000-808	95	44	.	.	PUNCT
dentistry3000-808	96	1	the	the	DET
dentistry3000-808	96	2	immunological	immunological	ADJ
dentistry3000-808	96	3	processes	process	NOUN
dentistry3000-808	96	4	resulting	result	VERB
dentistry3000-808	96	5	in	in	ADP
dentistry3000-808	96	6	advancing	advance	VERB
dentistry3000-808	96	7	connective	connective	ADJ
dentistry3000-808	96	8	tissue	tissue	NOUN
dentistry3000-808	96	9	breakdown	breakdown	NOUN
dentistry3000-808	96	10	and	and	CCONJ
dentistry3000-808	96	11	osseous	osseous	ADJ
dentistry3000-808	96	12	tissue	tissue	NOUN
dentistry3000-808	96	13	resorption	resorption	NOUN
dentistry3000-808	96	14	,	,	PUNCT
dentistry3000-808	96	15	typical	typical	ADJ
dentistry3000-808	96	16	of	of	ADP
dentistry3000-808	96	17	ra	ra	PROPN
dentistry3000-808	96	18	,	,	PUNCT
dentistry3000-808	96	19	are	be	AUX
dentistry3000-808	96	20	also	also	ADV
dentistry3000-808	96	21	common	common	ADJ
dentistry3000-808	96	22	in	in	ADP
dentistry3000-808	96	23	periodontal	periodontal	ADJ
dentistry3000-808	96	24	disease	disease	NOUN
dentistry3000-808	96	25	.	.	PUNCT
dentistry3000-808	97	1	periodontal	periodontal	ADJ
dentistry3000-808	97	2	disease	disease	NOUN
dentistry3000-808	97	3	,	,	PUNCT
dentistry3000-808	97	4	a	a	DET
dentistry3000-808	97	5	contagious	contagious	ADJ
dentistry3000-808	97	6	ailment	ailment	NOUN
dentistry3000-808	97	7	predominantly	predominantly	ADV
dentistry3000-808	97	8	induced	induce	VERB
dentistry3000-808	97	9	by	by	ADP
dentistry3000-808	97	10	bacterial	bacterial	ADJ
dentistry3000-808	97	11	species	specie	NOUN
dentistry3000-808	97	12	such	such	ADJ
dentistry3000-808	97	13	as	as	ADP
dentistry3000-808	97	14	p.	p.	PROPN
dentistry3000-808	97	15	gingivalis	gingivalis	PROPN
dentistry3000-808	97	16	,	,	PUNCT
dentistry3000-808	97	17	aggregatibacter	aggregatibacter	NOUN
dentistry3000-808	97	18	actinomycetemcomitans	actinomycetemcomitan	NOUN
dentistry3000-808	97	19	,	,	PUNCT
dentistry3000-808	97	20	tannerella	tannerella	NOUN
dentistry3000-808	97	21	forsythia	forsythia	NOUN
dentistry3000-808	97	22	,	,	PUNCT
dentistry3000-808	97	23	and	and	CCONJ
dentistry3000-808	97	24	treponema	treponema	VERB
dentistry3000-808	97	25	denticola	denticola	PROPN
dentistry3000-808	97	26	,	,	PUNCT
dentistry3000-808	97	27	elicits	elicit	VERB
dentistry3000-808	97	28	both	both	CCONJ
dentistry3000-808	97	29	localized	localized	ADJ
dentistry3000-808	97	30	and	and	CCONJ
dentistry3000-808	97	31	systemic	systemic	ADJ
dentistry3000-808	97	32	immunological	immunological	ADJ
dentistry3000-808	97	33	reactions	reaction	NOUN
dentistry3000-808	97	34	.	.	PUNCT
dentistry3000-808	98	1	furthermore	furthermore	ADV
dentistry3000-808	98	2	,	,	PUNCT
dentistry3000-808	98	3	the	the	DET
dentistry3000-808	98	4	presence	presence	NOUN
dentistry3000-808	98	5	of	of	ADP
dentistry3000-808	98	6	oral	oral	ADJ
dentistry3000-808	98	7	bacterial	bacterial	ADJ
dentistry3000-808	98	8	dna	dna	NOUN
dentistry3000-808	98	9	and	and	CCONJ
dentistry3000-808	98	10	antibodies	antibodie	VERB
dentistry3000-808	98	11	in	in	ADP
dentistry3000-808	98	12	the	the	DET
dentistry3000-808	98	13	synovial	synovial	ADJ
dentistry3000-808	98	14	fluid	fluid	NOUN
dentistry3000-808	98	15	and	and	CCONJ
dentistry3000-808	98	16	blood	blood	NOUN
dentistry3000-808	98	17	of	of	ADP
dentistry3000-808	98	18	patients	patient	NOUN
dentistry3000-808	98	19	with	with	ADP
dentistry3000-808	98	20	ra	ra	PROPN
dentistry3000-808	98	21	connect	connect	VERB
dentistry3000-808	98	22	pd	pd	PROPN
dentistry3000-808	98	23	with	with	ADP
dentistry3000-808	98	24	the	the	DET
dentistry3000-808	98	25	development	development	NOUN
dentistry3000-808	98	26	of	of	ADP
dentistry3000-808	98	27	ra	ra	PROPN
dentistry3000-808	99	1	[	[	X
dentistry3000-808	99	2	11	11	NUM
dentistry3000-808	99	3	,	,	PUNCT
dentistry3000-808	99	4	16	16	NUM
dentistry3000-808	99	5	]	]	PUNCT
dentistry3000-808	99	6	.	.	PUNCT
dentistry3000-808	100	1	a	a	DET
dentistry3000-808	100	2	potential	potential	ADJ
dentistry3000-808	100	3	correlation	correlation	NOUN
dentistry3000-808	100	4	between	between	ADP
dentistry3000-808	100	5	pd	pd	PROPN
dentistry3000-808	100	6	and	and	CCONJ
dentistry3000-808	100	7	ra	ra	PROPN
dentistry3000-808	100	8	may	may	AUX
dentistry3000-808	100	9	extend	extend	VERB
dentistry3000-808	100	10	beyond	beyond	ADP
dentistry3000-808	100	11	causative	causative	ADJ
dentistry3000-808	100	12	relationships	relationship	NOUN
dentistry3000-808	100	13	,	,	PUNCT
dentistry3000-808	100	14	presumably	presumably	ADV
dentistry3000-808	100	15	attributable	attributable	ADJ
dentistry3000-808	100	16	to	to	ADP
dentistry3000-808	100	17	prevalent	prevalent	ADJ
dentistry3000-808	100	18	genetic	genetic	ADJ
dentistry3000-808	100	19	and	and	CCONJ
dentistry3000-808	100	20	environmental	environmental	ADJ
dentistry3000-808	100	21	risk	risk	NOUN
dentistry3000-808	100	22	determinants	determinant	NOUN
dentistry3000-808	100	23	,	,	PUNCT
dentistry3000-808	100	24	including	include	VERB
dentistry3000-808	100	25	major	major	ADJ
dentistry3000-808	100	26	histocompatibility	histocompatibility	NOUN
dentistry3000-808	100	27	class	class	PROPN
dentistry3000-808	100	28	ii	ii	PROPN
dentistry3000-808	100	29	hla	hla	PROPN
dentistry3000-808	100	30	-	-	PUNCT
dentistry3000-808	100	31	drb1	drb1	NOUN
dentistry3000-808	100	32	allele	allele	NOUN
dentistry3000-808	100	33	expression	expression	NOUN
dentistry3000-808	100	34	and	and	CCONJ
dentistry3000-808	100	35	tobacco	tobacco	NOUN
dentistry3000-808	100	36	use	use	NOUN
dentistry3000-808	100	37	[	[	X
dentistry3000-808	100	38	11,38	11,38	NUM
dentistry3000-808	100	39	]	]	PUNCT
dentistry3000-808	100	40	.	.	PUNCT
dentistry3000-808	101	1	although	although	SCONJ
dentistry3000-808	101	2	the	the	DET
dentistry3000-808	101	3	underlying	underlying	ADJ
dentistry3000-808	101	4	causes	cause	NOUN
dentistry3000-808	101	5	differ	differ	VERB
dentistry3000-808	101	6	,	,	PUNCT
dentistry3000-808	101	7	numerous	numerous	ADJ
dentistry3000-808	101	8	clinical	clinical	ADJ
dentistry3000-808	101	9	and	and	CCONJ
dentistry3000-808	101	10	public	public	ADJ
dentistry3000-808	101	11	health	health	NOUN
dentistry3000-808	101	12	researchers	researcher	NOUN
dentistry3000-808	101	13	suggest	suggest	VERB
dentistry3000-808	101	14	a	a	DET
dentistry3000-808	101	15	link	link	NOUN
dentistry3000-808	101	16	between	between	ADP
dentistry3000-808	101	17	ra	ra	PROPN
dentistry3000-808	101	18	and	and	CCONJ
dentistry3000-808	101	19	pd	pd	PROPN
dentistry3000-808	101	20	.	.	PROPN
dentistry3000-808	101	21	individuals	individual	NOUN
dentistry3000-808	101	22	with	with	ADP
dentistry3000-808	101	23	pd	pd	PROPN
dentistry3000-808	101	24	have	have	VERB
dentistry3000-808	101	25	an	an	DET
dentistry3000-808	101	26	increased	increase	VERB
dentistry3000-808	101	27	susceptibility	susceptibility	NOUN
dentistry3000-808	101	28	to	to	ADP
dentistry3000-808	101	29	ra	ra	PROPN
dentistry3000-808	101	30	and	and	CCONJ
dentistry3000-808	101	31	vice	vice	ADV
dentistry3000-808	101	32	versa	versa	ADV
dentistry3000-808	101	33	;	;	PUNCT
dentistry3000-808	101	34	the	the	DET
dentistry3000-808	101	35	frequency	frequency	NOUN
dentistry3000-808	101	36	of	of	ADP
dentistry3000-808	101	37	pd	pd	PROPN
dentistry3000-808	101	38	is	be	AUX
dentistry3000-808	101	39	twice	twice	ADV
dentistry3000-808	101	40	as	as	ADV
dentistry3000-808	101	41	high	high	ADJ
dentistry3000-808	101	42	in	in	ADP
dentistry3000-808	101	43	ra	ra	PROPN
dentistry3000-808	101	44	individuals	individual	NOUN
dentistry3000-808	101	45	in	in	ADP
dentistry3000-808	101	46	comparison	comparison	NOUN
dentistry3000-808	101	47	to	to	ADP
dentistry3000-808	101	48	the	the	DET
dentistry3000-808	101	49	populace	populace	NOUN
dentistry3000-808	101	50	[	[	X
dentistry3000-808	101	51	11,37	11,37	X
dentistry3000-808	101	52	]	]	X
dentistry3000-808	101	53	.	.	PUNCT
dentistry3000-808	102	1	furthermore	furthermore	ADV
dentistry3000-808	102	2	,	,	PUNCT
dentistry3000-808	102	3	ra	ra	PROPN
dentistry3000-808	102	4	individuals	individual	NOUN
dentistry3000-808	102	5	with	with	ADP
dentistry3000-808	102	6	pd	pd	PROPN
dentistry3000-808	102	7	typically	typically	ADV
dentistry3000-808	102	8	exhibit	exhibit	VERB
dentistry3000-808	102	9	a	a	DET
dentistry3000-808	102	10	more	more	ADV
dentistry3000-808	102	11	serious	serious	ADJ
dentistry3000-808	102	12	clinical	clinical	ADJ
dentistry3000-808	102	13	progression	progression	NOUN
dentistry3000-808	102	14	,	,	PUNCT
dentistry3000-808	102	15	irrespective	irrespective	ADV
dentistry3000-808	102	16	of	of	ADP
dentistry3000-808	102	17	gender	gender	NOUN
dentistry3000-808	102	18	,	,	PUNCT
dentistry3000-808	102	19	age	age	NOUN
dentistry3000-808	102	20	,	,	PUNCT
dentistry3000-808	102	21	smoking	smoking	NOUN
dentistry3000-808	102	22	or	or	CCONJ
dentistry3000-808	102	23	ethnicity	ethnicity	NOUN
dentistry3000-808	102	24	status	status	NOUN
dentistry3000-808	102	25	,	,	PUNCT
dentistry3000-808	102	26	in	in	ADP
dentistry3000-808	102	27	comparison	comparison	NOUN
dentistry3000-808	102	28	to	to	ADP
dentistry3000-808	102	29	individuals	individual	NOUN
dentistry3000-808	102	30	without	without	ADP
dentistry3000-808	102	31	ra	ra	PROPN
dentistry3000-808	102	32	.	.	PUNCT
dentistry3000-808	103	1	moreover	moreover	ADV
dentistry3000-808	103	2	,	,	PUNCT
dentistry3000-808	103	3	the	the	DET
dentistry3000-808	103	4	two	two	NUM
dentistry3000-808	103	5	illnesses	illness	NOUN
dentistry3000-808	103	6	exhibit	exhibit	VERB
dentistry3000-808	103	7	analogous	analogous	ADJ
dentistry3000-808	103	8	pathways	pathway	NOUN
dentistry3000-808	103	9	of	of	ADP
dentistry3000-808	103	10	tissue	tissue	NOUN
dentistry3000-808	103	11	damage	damage	NOUN
dentistry3000-808	103	12	driven	drive	VERB
dentistry3000-808	103	13	by	by	ADP
dentistry3000-808	103	14	inflammatory	inflammatory	ADJ
dentistry3000-808	103	15	cells	cell	NOUN
dentistry3000-808	103	16	and	and	CCONJ
dentistry3000-808	103	17	proinflammatory	proinflammatory	ADJ
dentistry3000-808	103	18	cytokines	cytokine	NOUN
dentistry3000-808	103	19	,	,	PUNCT
dentistry3000-808	103	20	indicating	indicate	VERB
dentistry3000-808	103	21	that	that	SCONJ
dentistry3000-808	103	22	periodontal	periodontal	ADJ
dentistry3000-808	103	23	disease	disease	NOUN
dentistry3000-808	103	24	can	can	AUX
dentistry3000-808	103	25	contribute	contribute	VERB
dentistry3000-808	103	26	to	to	ADP
dentistry3000-808	103	27	the	the	DET
dentistry3000-808	103	28	onset	onset	NOUN
dentistry3000-808	103	29	and	and	CCONJ
dentistry3000-808	103	30	continuation	continuation	NOUN
dentistry3000-808	103	31	of	of	ADP
dentistry3000-808	103	32	autoimmune	autoimmune	ADJ
dentistry3000-808	103	33	inflammatory	inflammatory	ADJ
dentistry3000-808	103	34	responses	response	NOUN
dentistry3000-808	103	35	observed	observe	VERB
dentistry3000-808	103	36	in	in	ADP
dentistry3000-808	103	37	ra	ra	PROPN
dentistry3000-808	103	38	[	[	X
dentistry3000-808	103	39	11,39	11,39	NOUN
dentistry3000-808	103	40	]	]	PUNCT
dentistry3000-808	103	41	.	.	PUNCT
dentistry3000-808	104	1	role	role	NOUN
dentistry3000-808	104	2	of	of	ADP
dentistry3000-808	104	3	porphyromonas	porphyromona	NOUN
dentistry3000-808	104	4	gingivalis	gingivalis	VERB
dentistry3000-808	104	5	in	in	ADP
dentistry3000-808	104	6	the	the	DET
dentistry3000-808	104	7	development	development	NOUN
dentistry3000-808	104	8	of	of	ADP
dentistry3000-808	104	9	rheumatoid	rheumatoid	NOUN
dentistry3000-808	104	10	arthritis	arthritis	NOUN
dentistry3000-808	104	11	the	the	DET
dentistry3000-808	104	12	successful	successful	ADJ
dentistry3000-808	104	13	application	application	NOUN
dentistry3000-808	104	14	of	of	ADP
dentistry3000-808	104	15	antibiotics	antibiotic	NOUN
dentistry3000-808	104	16	for	for	ADP
dentistry3000-808	104	17	anaerobic	anaerobic	ADJ
dentistry3000-808	104	18	microbial	microbial	ADJ
dentistry3000-808	104	19	infections	infection	NOUN
dentistry3000-808	104	20	in	in	ADP
dentistry3000-808	104	21	ra	ra	PROPN
dentistry3000-808	104	22	suggests	suggest	VERB
dentistry3000-808	104	23	that	that	SCONJ
dentistry3000-808	104	24	bacteria	bacteria	NOUN
dentistry3000-808	104	25	may	may	AUX
dentistry3000-808	104	26	contribute	contribute	VERB
dentistry3000-808	104	27	to	to	ADP
dentistry3000-808	104	28	the	the	DET
dentistry3000-808	104	29	formation	formation	NOUN
dentistry3000-808	104	30	of	of	ADP
dentistry3000-808	104	31	ra	ra	PROPN
dentistry3000-808	104	32	.	.	PUNCT
dentistry3000-808	105	1	identification	identification	NOUN
dentistry3000-808	105	2	of	of	ADP
dentistry3000-808	105	3	bacterial	bacterial	ADJ
dentistry3000-808	105	4	dna	dna	NOUN
dentistry3000-808	105	5	from	from	ADP
dentistry3000-808	105	6	anaerobes	anaerobe	NOUN
dentistry3000-808	105	7	and	and	CCONJ
dentistry3000-808	105	8	elevated	elevated	ADJ
dentistry3000-808	105	9	antibody	antibody	NOUN
dentistry3000-808	105	10	titers	titer	NOUN
dentistry3000-808	105	11	opposed	oppose	VERB
dentistry3000-808	105	12	to	to	ADP
dentistry3000-808	105	13	it	it	PRON
dentistry3000-808	105	14	in	in	ADP
dentistry3000-808	105	15	the	the	DET
dentistry3000-808	105	16	synovial	synovial	ADJ
dentistry3000-808	105	17	fluid	fluid	NOUN
dentistry3000-808	105	18	and	and	CCONJ
dentistry3000-808	105	19	serum	serum	NOUN
dentistry3000-808	105	20	of	of	ADP
dentistry3000-808	105	21	ra	ra	PROPN
dentistry3000-808	105	22	individuals	individual	NOUN
dentistry3000-808	105	23	at	at	ADP
dentistry3000-808	105	24	different	different	ADJ
dentistry3000-808	105	25	disease	disease	NOUN
dentistry3000-808	105	26	phases	phase	NOUN
dentistry3000-808	105	27	supports	support	VERB
dentistry3000-808	105	28	the	the	DET
dentistry3000-808	105	29	hypothesis	hypothesis	NOUN
dentistry3000-808	105	30	that	that	PRON
dentistry3000-808	105	31	oral	oral	ADJ
dentistry3000-808	105	32	infections	infection	NOUN
dentistry3000-808	105	33	contribute	contribute	VERB
dentistry3000-808	105	34	to	to	ADP
dentistry3000-808	105	35	the	the	DET
dentistry3000-808	105	36	etiology	etiology	NOUN
dentistry3000-808	105	37	of	of	ADP
dentistry3000-808	105	38	ra	ra	PROPN
dentistry3000-808	106	1	[	[	X
dentistry3000-808	106	2	11,40	11,40	NUM
dentistry3000-808	106	3	]	]	PUNCT
dentistry3000-808	106	4	.	.	PUNCT
dentistry3000-808	107	1	periodontal	periodontal	ADJ
dentistry3000-808	107	2	pathogens	pathogen	NOUN
dentistry3000-808	107	3	such	such	ADJ
dentistry3000-808	107	4	as	as	ADP
dentistry3000-808	107	5	p.	p.	PROPN
dentistry3000-808	107	6	gingivalis	gingivalis	PROPN
dentistry3000-808	107	7	can	can	AUX
dentistry3000-808	107	8	undermine	undermine	VERB
dentistry3000-808	107	9	the	the	DET
dentistry3000-808	107	10	integrity	integrity	NOUN
dentistry3000-808	107	11	of	of	ADP
dentistry3000-808	107	12	epithelial	epithelial	ADJ
dentistry3000-808	107	13	tissue	tissue	NOUN
dentistry3000-808	107	14	,	,	PUNCT
dentistry3000-808	107	15	infiltrate	infiltrate	VERB
dentistry3000-808	107	16	human	human	ADJ
dentistry3000-808	107	17	endothelial	endothelial	NOUN
dentistry3000-808	107	18	cells	cell	NOUN
dentistry3000-808	107	19	,	,	PUNCT
dentistry3000-808	107	20	and	and	CCONJ
dentistry3000-808	107	21	affect	affect	VERB
dentistry3000-808	107	22	transcription	transcription	NOUN
dentistry3000-808	107	23	and	and	CCONJ
dentistry3000-808	107	24	protein	protein	NOUN
dentistry3000-808	107	25	synthesis	synthesis	NOUN
dentistry3000-808	107	26	,	,	PUNCT
dentistry3000-808	107	27	thereby	thereby	ADV
dentistry3000-808	107	28	facilitating	facilitate	VERB
dentistry3000-808	107	29	direct	direct	ADJ
dentistry3000-808	107	30	systemic	systemic	ADJ
dentistry3000-808	107	31	entry	entry	NOUN
dentistry3000-808	107	32	into	into	ADP
dentistry3000-808	107	33	bloodstream	bloodstream	NOUN
dentistry3000-808	107	34	.	.	PUNCT
dentistry3000-808	108	1	p.	p.	NOUN
dentistry3000-808	108	2	gingivalis	gingivalis	PROPN
dentistry3000-808	108	3	can	can	AUX
dentistry3000-808	108	4	infiltrate	infiltrate	VERB
dentistry3000-808	108	5	primary	primary	ADJ
dentistry3000-808	108	6	human	human	ADJ
dentistry3000-808	108	7	poten&al	poten&al	PROPN
dentistry3000-808	108	8	role	role	NOUN
dentistry3000-808	108	9	of	of	ADP
dentistry3000-808	108	10	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	108	11	in	in	ADP
dentistry3000-808	108	12	rheumatoid	rheumatoid	NOUN
dentistry3000-808	108	13	arthri&s	arthri&s	PROPN
dentistry3000-808	108	14	vol	vol	NOUN
dentistry3000-808	108	15	13	13	NUM
dentistry3000-808	108	16	no	no	DET
dentistry3000-808	108	17	1	1	NUM
dentistry3000-808	108	18	(	(	PUNCT
dentistry3000-808	108	19	2025	2025	NUM
dentistry3000-808	108	20	)	)	PUNCT
dentistry3000-808	108	21	doi	doi	NOUN
dentistry3000-808	108	22	10.5195	10.5195	NUM
dentistry3000-808	108	23	/	/	SYM
dentistry3000-808	108	24	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	108	25	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	108	26	chondrocytes	chondrocyte	NOUN
dentistry3000-808	108	27	derived	derive	VERB
dentistry3000-808	108	28	from	from	ADP
dentistry3000-808	108	29	patellar	patellar	ADJ
dentistry3000-808	108	30	joints	joint	NOUN
dentistry3000-808	108	31	,	,	PUNCT
dentistry3000-808	108	32	leading	lead	VERB
dentistry3000-808	108	33	to	to	ADP
dentistry3000-808	108	34	prolonged	prolonged	ADJ
dentistry3000-808	108	35	cell	cell	NOUN
dentistry3000-808	108	36	cycle	cycle	NOUN
dentistry3000-808	108	37	advancement	advancement	NOUN
dentistry3000-808	108	38	and	and	CCONJ
dentistry3000-808	108	39	heightened	heighten	VERB
dentistry3000-808	108	40	programmed	program	VERB
dentistry3000-808	108	41	cell	cell	NOUN
dentistry3000-808	108	42	death	death	NOUN
dentistry3000-808	109	1	[	[	X
dentistry3000-808	109	2	11	11	NUM
dentistry3000-808	109	3	]	]	PUNCT
dentistry3000-808	109	4	.	.	PUNCT
dentistry3000-808	110	1	p.	p.	NOUN
dentistry3000-808	110	2	gingivalis	gingivali	VERB
dentistry3000-808	110	3	synthesizes	synthesize	VERB
dentistry3000-808	110	4	cysteine	cysteine	NOUN
dentistry3000-808	110	5	endopeptidase	endopeptidase	NOUN
dentistry3000-808	110	6	enzymes	enzyme	NOUN
dentistry3000-808	110	7	which	which	PRON
dentistry3000-808	110	8	are	be	AUX
dentistry3000-808	110	9	essential	essential	ADJ
dentistry3000-808	110	10	for	for	ADP
dentistry3000-808	110	11	bacterial	bacterial	ADJ
dentistry3000-808	110	12	homeostasis	homeostasis	NOUN
dentistry3000-808	110	13	and	and	CCONJ
dentistry3000-808	110	14	infection	infection	NOUN
dentistry3000-808	110	15	mechanisms	mechanism	NOUN
dentistry3000-808	110	16	,	,	PUNCT
dentistry3000-808	110	17	including	include	VERB
dentistry3000-808	110	18	amino	amino	ADJ
dentistry3000-808	110	19	acids	acid	NOUN
dentistry3000-808	110	20	isolation	isolation	NOUN
dentistry3000-808	110	21	from	from	ADP
dentistry3000-808	110	22	host	host	NOUN
dentistry3000-808	110	23	and	and	CCONJ
dentistry3000-808	110	24	the	the	DET
dentistry3000-808	110	25	formation	formation	NOUN
dentistry3000-808	110	26	of	of	ADP
dentistry3000-808	110	27	fimbriae	fimbriae	NOUN
dentistry3000-808	110	28	[	[	X
dentistry3000-808	110	29	11,25	11,25	NUM
dentistry3000-808	110	30	]	]	PUNCT
dentistry3000-808	110	31	.	.	PUNCT
dentistry3000-808	111	1	p.	p.	NOUN
dentistry3000-808	111	2	gingivalis	gingivalis	PROPN
dentistry3000-808	112	1	gingipains	gingipain	NOUN
dentistry3000-808	112	2	facilitate	facilitate	VERB
dentistry3000-808	112	3	proteolytic	proteolytic	ADJ
dentistry3000-808	112	4	enzymes	enzyme	NOUN
dentistry3000-808	112	5	activation	activation	NOUN
dentistry3000-808	112	6	including	include	VERB
dentistry3000-808	112	7	mmp-1	mmp-1	ADP
dentistry3000-808	112	8	,	,	PUNCT
dentistry3000-808	112	9	mmp-3	mmp-3	NOUN
dentistry3000-808	112	10	,	,	PUNCT
dentistry3000-808	112	11	and	and	CCONJ
dentistry3000-808	112	12	mmp-9	mmp-9	NUM
dentistry3000-808	112	13	,	,	PUNCT
dentistry3000-808	112	14	along	along	ADP
dentistry3000-808	112	15	with	with	ADP
dentistry3000-808	112	16	the	the	DET
dentistry3000-808	112	17	degradation	degradation	NOUN
dentistry3000-808	112	18	of	of	ADP
dentistry3000-808	112	19	extracellular	extracellular	ADJ
dentistry3000-808	112	20	matrix	matrix	NOUN
dentistry3000-808	112	21	host	host	NOUN
dentistry3000-808	112	22	proteins	protein	NOUN
dentistry3000-808	112	23	such	such	ADJ
dentistry3000-808	112	24	as	as	ADP
dentistry3000-808	112	25	collagen	collagen	NOUN
dentistry3000-808	112	26	,	,	PUNCT
dentistry3000-808	112	27	fibronectin	fibronectin	NOUN
dentistry3000-808	112	28	,	,	PUNCT
dentistry3000-808	112	29	and	and	CCONJ
dentistry3000-808	112	30	laminin	laminin	NOUN
dentistry3000-808	112	31	.	.	PUNCT
dentistry3000-808	113	1	additionally	additionally	ADV
dentistry3000-808	113	2	,	,	PUNCT
dentistry3000-808	113	3	gingipains	gingipain	NOUN
dentistry3000-808	113	4	induce	induce	VERB
dentistry3000-808	113	5	the	the	DET
dentistry3000-808	113	6	degradation	degradation	NOUN
dentistry3000-808	113	7	of	of	ADP
dentistry3000-808	113	8	complement	complement	NOUN
dentistry3000-808	113	9	factors	factor	NOUN
dentistry3000-808	113	10	and	and	CCONJ
dentistry3000-808	113	11	enhance	enhance	VERB
dentistry3000-808	113	12	the	the	DET
dentistry3000-808	113	13	permeability	permeability	NOUN
dentistry3000-808	113	14	of	of	ADP
dentistry3000-808	113	15	blood	blood	NOUN
dentistry3000-808	113	16	vessels	vessel	NOUN
dentistry3000-808	113	17	[	[	X
dentistry3000-808	113	18	11,41	11,41	NUM
dentistry3000-808	113	19	]	]	X
dentistry3000-808	113	20	.	.	PUNCT
dentistry3000-808	114	1	the	the	DET
dentistry3000-808	114	2	pathogenesis	pathogenesis	NOUN
dentistry3000-808	114	3	of	of	ADP
dentistry3000-808	114	4	ra	ra	PROPN
dentistry3000-808	114	5	is	be	AUX
dentistry3000-808	114	6	associated	associate	VERB
dentistry3000-808	114	7	with	with	ADP
dentistry3000-808	114	8	the	the	DET
dentistry3000-808	114	9	involvement	involvement	NOUN
dentistry3000-808	114	10	of	of	ADP
dentistry3000-808	114	11	p.	p.	PROPN
dentistry3000-808	114	12	gingivalis	gingivalis	PROPN
dentistry3000-808	114	13	in	in	ADP
dentistry3000-808	114	14	the	the	DET
dentistry3000-808	114	15	process	process	NOUN
dentistry3000-808	114	16	of	of	ADP
dentistry3000-808	114	17	citrullination	citrullination	NOUN
dentistry3000-808	114	18	.	.	PUNCT
dentistry3000-808	115	1	proteins	protein	NOUN
dentistry3000-808	115	2	experience	experience	VERB
dentistry3000-808	115	3	a	a	DET
dentistry3000-808	115	4	post	post	ADJ
dentistry3000-808	115	5	-	-	ADJ
dentistry3000-808	115	6	translational	translational	ADJ
dentistry3000-808	115	7	modification	modification	NOUN
dentistry3000-808	115	8	known	know	VERB
dentistry3000-808	115	9	as	as	ADP
dentistry3000-808	115	10	citrullination	citrullination	NOUN
dentistry3000-808	115	11	,	,	PUNCT
dentistry3000-808	115	12	converting	convert	VERB
dentistry3000-808	115	13	arginine	arginine	NOUN
dentistry3000-808	115	14	residues	residue	NOUN
dentistry3000-808	115	15	into	into	ADP
dentistry3000-808	115	16	citrulline	citrulline	NOUN
dentistry3000-808	115	17	[	[	X
dentistry3000-808	115	18	8,42	8,42	NOUN
dentistry3000-808	115	19	]	]	X
dentistry3000-808	115	20	.	.	PUNCT
dentistry3000-808	116	1	the	the	DET
dentistry3000-808	116	2	bacterium	bacterium	NOUN
dentistry3000-808	116	3	produces	produce	VERB
dentistry3000-808	116	4	enzymes	enzyme	NOUN
dentistry3000-808	116	5	,	,	PUNCT
dentistry3000-808	116	6	including	include	VERB
dentistry3000-808	116	7	padi	padi	NOUN
dentistry3000-808	116	8	,	,	PUNCT
dentistry3000-808	116	9	catalyze	catalyze	NOUN
dentistry3000-808	116	10	citrullination	citrullination	NOUN
dentistry3000-808	116	11	.	.	PUNCT
dentistry3000-808	117	1	the	the	DET
dentistry3000-808	117	2	infection	infection	NOUN
dentistry3000-808	117	3	elicits	elicit	VERB
dentistry3000-808	117	4	immunological	immunological	ADJ
dentistry3000-808	117	5	reaction	reaction	NOUN
dentistry3000-808	117	6	which	which	PRON
dentistry3000-808	117	7	can	can	AUX
dentistry3000-808	117	8	lead	lead	VERB
dentistry3000-808	117	9	to	to	ADP
dentistry3000-808	117	10	systemic	systemic	ADJ
dentistry3000-808	117	11	consequences	consequence	NOUN
dentistry3000-808	117	12	.	.	PUNCT
dentistry3000-808	118	1	citrullination	citrullination	NOUN
dentistry3000-808	118	2	is	be	AUX
dentistry3000-808	118	3	a	a	DET
dentistry3000-808	118	4	pivotal	pivotal	ADJ
dentistry3000-808	118	5	process	process	NOUN
dentistry3000-808	118	6	in	in	ADP
dentistry3000-808	118	7	the	the	DET
dentistry3000-808	118	8	pathogenesis	pathogenesis	NOUN
dentistry3000-808	118	9	of	of	ADP
dentistry3000-808	118	10	ra	ra	PROPN
dentistry3000-808	118	11	,	,	PUNCT
dentistry3000-808	118	12	as	as	SCONJ
dentistry3000-808	118	13	it	it	PRON
dentistry3000-808	118	14	generates	generate	VERB
dentistry3000-808	118	15	antibodies	antibody	NOUN
dentistry3000-808	118	16	against	against	ADP
dentistry3000-808	118	17	citrullinated	citrullinate	VERB
dentistry3000-808	118	18	proteins	protein	NOUN
dentistry3000-808	118	19	[	[	X
dentistry3000-808	118	20	8,43	8,43	NOUN
dentistry3000-808	118	21	]	]	PUNCT
dentistry3000-808	118	22	.	.	PUNCT
dentistry3000-808	119	1	the	the	DET
dentistry3000-808	119	2	citrullination	citrullination	NOUN
dentistry3000-808	119	3	mediated	mediate	VERB
dentistry3000-808	119	4	by	by	ADP
dentistry3000-808	119	5	p.	p.	PROPN
dentistry3000-808	119	6	gingivalis	gingivalis	PROPN
dentistry3000-808	119	7	may	may	AUX
dentistry3000-808	119	8	facilitate	facilitate	VERB
dentistry3000-808	119	9	the	the	DET
dentistry3000-808	119	10	production	production	NOUN
dentistry3000-808	119	11	of	of	ADP
dentistry3000-808	119	12	acpas	acpas	NOUN
dentistry3000-808	119	13	,	,	PUNCT
dentistry3000-808	119	14	establishing	establish	VERB
dentistry3000-808	119	15	a	a	DET
dentistry3000-808	119	16	connection	connection	NOUN
dentistry3000-808	119	17	between	between	ADP
dentistry3000-808	119	18	periodontal	periodontal	ADJ
dentistry3000-808	119	19	disease	disease	NOUN
dentistry3000-808	119	20	and	and	CCONJ
dentistry3000-808	119	21	the	the	DET
dentistry3000-808	119	22	onset	onset	NOUN
dentistry3000-808	119	23	or	or	CCONJ
dentistry3000-808	119	24	worsening	worsening	NOUN
dentistry3000-808	119	25	of	of	ADP
dentistry3000-808	119	26	ra	ra	PROPN
dentistry3000-808	119	27	.	.	PUNCT
dentistry3000-808	120	1	citrullinated	citrullinate	VERB
dentistry3000-808	120	2	proteins	protein	NOUN
dentistry3000-808	120	3	are	be	AUX
dentistry3000-808	120	4	commonly	commonly	ADV
dentistry3000-808	120	5	present	present	ADJ
dentistry3000-808	120	6	in	in	ADP
dentistry3000-808	120	7	the	the	DET
dentistry3000-808	120	8	synovial	synovial	ADJ
dentistry3000-808	120	9	fluids	fluid	NOUN
dentistry3000-808	120	10	of	of	ADP
dentistry3000-808	120	11	people	people	NOUN
dentistry3000-808	120	12	with	with	ADP
dentistry3000-808	120	13	ra	ra	PROPN
dentistry3000-808	120	14	.	.	PUNCT
dentistry3000-808	121	1	the	the	DET
dentistry3000-808	121	2	existence	existence	NOUN
dentistry3000-808	121	3	of	of	ADP
dentistry3000-808	121	4	p.	p.	PROPN
dentistry3000-808	121	5	gingivalis	gingivalis	PROPN
dentistry3000-808	121	6	and	and	CCONJ
dentistry3000-808	121	7	its	its	PRON
dentistry3000-808	121	8	citrullination	citrullination	NOUN
dentistry3000-808	121	9	role	role	NOUN
dentistry3000-808	121	10	inside	inside	ADP
dentistry3000-808	121	11	of	of	ADP
dentistry3000-808	121	12	the	the	DET
dentistry3000-808	121	13	mouth	mouth	NOUN
dentistry3000-808	121	14	may	may	AUX
dentistry3000-808	121	15	affect	affect	VERB
dentistry3000-808	121	16	the	the	DET
dentistry3000-808	121	17	systemic	systemic	ADJ
dentistry3000-808	121	18	dissemination	dissemination	NOUN
dentistry3000-808	121	19	of	of	ADP
dentistry3000-808	121	20	citrullinated	citrullinate	VERB
dentistry3000-808	121	21	peptides	peptide	NOUN
dentistry3000-808	121	22	,	,	PUNCT
dentistry3000-808	121	23	intensifying	intensify	VERB
dentistry3000-808	121	24	synovial	synovial	ADJ
dentistry3000-808	121	25	inflammation	inflammation	NOUN
dentistry3000-808	121	26	in	in	ADP
dentistry3000-808	121	27	predisposed	predisposed	ADJ
dentistry3000-808	121	28	people	people	NOUN
dentistry3000-808	122	1	[	[	X
dentistry3000-808	122	2	36,43	36,43	NOUN
dentistry3000-808	122	3	]	]	PUNCT
dentistry3000-808	122	4	.	.	PUNCT
dentistry3000-808	123	1	conclusion	conclusion	NOUN
dentistry3000-808	123	2	the	the	DET
dentistry3000-808	123	3	growing	grow	VERB
dentistry3000-808	123	4	body	body	NOUN
dentistry3000-808	123	5	of	of	ADP
dentistry3000-808	123	6	evidence	evidence	NOUN
dentistry3000-808	123	7	linking	link	VERB
dentistry3000-808	123	8	periodontitis	periodontitis	NOUN
dentistry3000-808	123	9	,	,	PUNCT
dentistry3000-808	123	10	particularly	particularly	ADV
dentistry3000-808	123	11	the	the	DET
dentistry3000-808	123	12	role	role	NOUN
dentistry3000-808	123	13	of	of	ADP
dentistry3000-808	123	14	p.	p.	PROPN
dentistry3000-808	123	15	gingivalis	gingivalis	PROPN
dentistry3000-808	123	16	,	,	PUNCT
dentistry3000-808	123	17	to	to	ADP
dentistry3000-808	123	18	the	the	DET
dentistry3000-808	123	19	development	development	NOUN
dentistry3000-808	123	20	and	and	CCONJ
dentistry3000-808	123	21	exacerbation	exacerbation	NOUN
dentistry3000-808	123	22	of	of	ADP
dentistry3000-808	123	23	ra	ra	PROPN
dentistry3000-808	123	24	highlights	highlight	NOUN
dentistry3000-808	123	25	the	the	DET
dentistry3000-808	123	26	complex	complex	ADJ
dentistry3000-808	123	27	interactions	interaction	NOUN
dentistry3000-808	123	28	between	between	ADP
dentistry3000-808	123	29	oral	oral	ADJ
dentistry3000-808	123	30	and	and	CCONJ
dentistry3000-808	123	31	systemic	systemic	ADJ
dentistry3000-808	123	32	health	health	NOUN
dentistry3000-808	123	33	.	.	PUNCT
dentistry3000-808	124	1	periodontitis	periodontitis	NOUN
dentistry3000-808	124	2	,	,	PUNCT
dentistry3000-808	124	3	a	a	DET
dentistry3000-808	124	4	chronic	chronic	ADJ
dentistry3000-808	124	5	inflammatory	inflammatory	ADJ
dentistry3000-808	124	6	disease	disease	NOUN
dentistry3000-808	124	7	,	,	PUNCT
dentistry3000-808	124	8	is	be	AUX
dentistry3000-808	124	9	associated	associate	VERB
dentistry3000-808	124	10	with	with	ADP
dentistry3000-808	124	11	a	a	DET
dentistry3000-808	124	12	range	range	NOUN
dentistry3000-808	124	13	of	of	ADP
dentistry3000-808	124	14	systemic	systemic	ADJ
dentistry3000-808	124	15	conditions	condition	NOUN
dentistry3000-808	124	16	,	,	PUNCT
dentistry3000-808	124	17	with	with	ADP
dentistry3000-808	124	18	ra	ra	PROPN
dentistry3000-808	124	19	being	be	AUX
dentistry3000-808	124	20	one	one	NUM
dentistry3000-808	124	21	of	of	ADP
dentistry3000-808	124	22	the	the	DET
dentistry3000-808	124	23	most	most	ADV
dentistry3000-808	124	24	compelling	compelling	ADJ
dentistry3000-808	124	25	examples	example	NOUN
dentistry3000-808	124	26	of	of	ADP
dentistry3000-808	124	27	such	such	ADJ
dentistry3000-808	124	28	connections	connection	NOUN
dentistry3000-808	124	29	.	.	PUNCT
dentistry3000-808	125	1	the	the	DET
dentistry3000-808	125	2	key	key	ADJ
dentistry3000-808	125	3	periodontal	periodontal	ADJ
dentistry3000-808	125	4	pathogen	pathogen	NOUN
dentistry3000-808	125	5	p.	p.	NOUN
dentistry3000-808	125	6	gingivalis	gingivalis	PROPN
dentistry3000-808	125	7	plays	play	VERB
dentistry3000-808	125	8	a	a	DET
dentistry3000-808	125	9	central	central	ADJ
dentistry3000-808	125	10	role	role	NOUN
dentistry3000-808	125	11	in	in	ADP
dentistry3000-808	125	12	this	this	DET
dentistry3000-808	125	13	relationship	relationship	NOUN
dentistry3000-808	125	14	,	,	PUNCT
dentistry3000-808	125	15	not	not	PART
dentistry3000-808	125	16	only	only	ADV
dentistry3000-808	125	17	by	by	ADP
dentistry3000-808	125	18	inducing	induce	VERB
dentistry3000-808	125	19	local	local	ADJ
dentistry3000-808	125	20	inflammation	inflammation	NOUN
dentistry3000-808	125	21	and	and	CCONJ
dentistry3000-808	125	22	bone	bone	NOUN
dentistry3000-808	125	23	resorption	resorption	NOUN
dentistry3000-808	125	24	in	in	ADP
dentistry3000-808	125	25	the	the	DET
dentistry3000-808	125	26	oral	oral	ADJ
dentistry3000-808	125	27	cavity	cavity	NOUN
dentistry3000-808	125	28	but	but	CCONJ
dentistry3000-808	125	29	also	also	ADV
dentistry3000-808	125	30	by	by	ADP
dentistry3000-808	125	31	influencing	influence	VERB
dentistry3000-808	125	32	systemic	systemic	ADJ
dentistry3000-808	125	33	immune	immune	ADJ
dentistry3000-808	125	34	responses	response	NOUN
dentistry3000-808	125	35	through	through	ADP
dentistry3000-808	125	36	mechanisms	mechanism	NOUN
dentistry3000-808	125	37	such	such	ADJ
dentistry3000-808	125	38	as	as	ADP
dentistry3000-808	125	39	citrullination	citrullination	NOUN
dentistry3000-808	125	40	.	.	PUNCT
dentistry3000-808	126	1	p.	p.	NOUN
dentistry3000-808	126	2	gingivalis	gingivalis	PROPN
dentistry3000-808	126	3	secretes	secrete	NOUN
dentistry3000-808	126	4	padi	padi	PROPN
dentistry3000-808	126	5	,	,	PUNCT
dentistry3000-808	126	6	an	an	DET
dentistry3000-808	126	7	enzyme	enzyme	NOUN
dentistry3000-808	126	8	that	that	PRON
dentistry3000-808	126	9	catalyzes	catalyze	VERB
dentistry3000-808	126	10	the	the	DET
dentistry3000-808	126	11	conversion	conversion	NOUN
dentistry3000-808	126	12	of	of	ADP
dentistry3000-808	126	13	arginine	arginine	NOUN
dentistry3000-808	126	14	to	to	PART
dentistry3000-808	126	15	citrulline	citrulline	VERB
dentistry3000-808	126	16	,	,	PUNCT
dentistry3000-808	126	17	a	a	DET
dentistry3000-808	126	18	critical	critical	ADJ
dentistry3000-808	126	19	process	process	NOUN
dentistry3000-808	126	20	that	that	PRON
dentistry3000-808	126	21	generates	generate	VERB
dentistry3000-808	126	22	autoantibodies	autoantibody	NOUN
dentistry3000-808	126	23	against	against	ADP
dentistry3000-808	126	24	citrullinated	citrullinate	VERB
dentistry3000-808	126	25	proteins	protein	NOUN
dentistry3000-808	126	26	,	,	PUNCT
dentistry3000-808	126	27	a	a	DET
dentistry3000-808	126	28	hallmark	hallmark	NOUN
dentistry3000-808	126	29	of	of	ADP
dentistry3000-808	126	30	ra	ra	PROPN
dentistry3000-808	126	31	.	.	PUNCT
dentistry3000-808	127	1	this	this	DET
dentistry3000-808	127	2	molecular	molecular	ADJ
dentistry3000-808	127	3	interaction	interaction	NOUN
dentistry3000-808	127	4	suggests	suggest	VERB
dentistry3000-808	127	5	that	that	SCONJ
dentistry3000-808	127	6	oral	oral	ADJ
dentistry3000-808	127	7	bacteria	bacteria	NOUN
dentistry3000-808	127	8	may	may	AUX
dentistry3000-808	127	9	directly	directly	ADV
dentistry3000-808	127	10	contribute	contribute	VERB
dentistry3000-808	127	11	to	to	ADP
dentistry3000-808	127	12	the	the	DET
dentistry3000-808	127	13	immune	immune	ADJ
dentistry3000-808	127	14	dysregulation	dysregulation	NOUN
dentistry3000-808	127	15	observed	observe	VERB
dentistry3000-808	127	16	in	in	ADP
dentistry3000-808	127	17	ra	ra	PROPN
dentistry3000-808	127	18	,	,	PUNCT
dentistry3000-808	127	19	leading	lead	VERB
dentistry3000-808	127	20	to	to	ADP
dentistry3000-808	127	21	the	the	DET
dentistry3000-808	127	22	production	production	NOUN
dentistry3000-808	127	23	of	of	ADP
dentistry3000-808	127	24	acpa	acpa	PRON
dentistry3000-808	127	25	and	and	CCONJ
dentistry3000-808	127	26	the	the	DET
dentistry3000-808	127	27	subsequent	subsequent	ADJ
dentistry3000-808	127	28	development	development	NOUN
dentistry3000-808	127	29	of	of	ADP
dentistry3000-808	127	30	chronic	chronic	ADJ
dentistry3000-808	127	31	joint	joint	ADJ
dentistry3000-808	127	32	inflammation	inflammation	NOUN
dentistry3000-808	127	33	.	.	PUNCT
dentistry3000-808	128	1	additionally	additionally	ADV
dentistry3000-808	128	2	,	,	PUNCT
dentistry3000-808	128	3	the	the	DET
dentistry3000-808	128	4	shared	share	VERB
dentistry3000-808	128	5	inflammatory	inflammatory	ADJ
dentistry3000-808	128	6	mediators	mediator	NOUN
dentistry3000-808	128	7	and	and	CCONJ
dentistry3000-808	128	8	cytokine	cytokine	ADJ
dentistry3000-808	128	9	profiles	profile	NOUN
dentistry3000-808	128	10	between	between	ADP
dentistry3000-808	128	11	pd	pd	PROPN
dentistry3000-808	128	12	and	and	CCONJ
dentistry3000-808	128	13	ra	ra	PROPN
dentistry3000-808	128	14	further	far	ADV
dentistry3000-808	128	15	reinforce	reinforce	VERB
dentistry3000-808	128	16	the	the	DET
dentistry3000-808	128	17	potential	potential	NOUN
dentistry3000-808	128	18	for	for	ADP
dentistry3000-808	128	19	a	a	DET
dentistry3000-808	128	20	bidirectional	bidirectional	ADJ
dentistry3000-808	128	21	relationship	relationship	NOUN
dentistry3000-808	128	22	,	,	PUNCT
dentistry3000-808	128	23	where	where	SCONJ
dentistry3000-808	128	24	one	one	NUM
dentistry3000-808	128	25	condition	condition	NOUN
dentistry3000-808	128	26	may	may	AUX
dentistry3000-808	128	27	influence	influence	VERB
dentistry3000-808	128	28	the	the	DET
dentistry3000-808	128	29	progression	progression	NOUN
dentistry3000-808	128	30	of	of	ADP
dentistry3000-808	128	31	the	the	DET
dentistry3000-808	128	32	other	other	ADJ
dentistry3000-808	128	33	.	.	PUNCT
dentistry3000-808	129	1	given	give	VERB
dentistry3000-808	129	2	the	the	DET
dentistry3000-808	129	3	significant	significant	ADJ
dentistry3000-808	129	4	prevalence	prevalence	NOUN
dentistry3000-808	129	5	of	of	ADP
dentistry3000-808	129	6	periodontitis	periodontitis	NOUN
dentistry3000-808	129	7	worldwide	worldwide	ADV
dentistry3000-808	129	8	,	,	PUNCT
dentistry3000-808	129	9	and	and	CCONJ
dentistry3000-808	129	10	the	the	DET
dentistry3000-808	129	11	established	establish	VERB
dentistry3000-808	129	12	connection	connection	NOUN
dentistry3000-808	129	13	between	between	ADP
dentistry3000-808	129	14	periodontal	periodontal	ADJ
dentistry3000-808	129	15	disease	disease	NOUN
dentistry3000-808	129	16	and	and	CCONJ
dentistry3000-808	129	17	ra	ra	NOUN
dentistry3000-808	129	18	,	,	PUNCT
dentistry3000-808	129	19	there	there	PRON
dentistry3000-808	129	20	is	be	VERB
dentistry3000-808	129	21	a	a	DET
dentistry3000-808	129	22	pressing	press	VERB
dentistry3000-808	129	23	need	need	NOUN
dentistry3000-808	129	24	for	for	ADP
dentistry3000-808	129	25	further	further	ADJ
dentistry3000-808	129	26	research	research	NOUN
dentistry3000-808	129	27	into	into	ADP
dentistry3000-808	129	28	the	the	DET
dentistry3000-808	129	29	underlying	underlie	VERB
dentistry3000-808	129	30	mechanisms	mechanism	NOUN
dentistry3000-808	129	31	of	of	ADP
dentistry3000-808	129	32	this	this	DET
dentistry3000-808	129	33	association	association	NOUN
dentistry3000-808	129	34	.	.	PUNCT
dentistry3000-808	130	1	understanding	understand	VERB
dentistry3000-808	130	2	how	how	SCONJ
dentistry3000-808	130	3	p.	p.	NOUN
dentistry3000-808	130	4	gingivalis	gingivalis	PROPN
dentistry3000-808	130	5	and	and	CCONJ
dentistry3000-808	130	6	other	other	ADJ
dentistry3000-808	130	7	periodontal	periodontal	ADJ
dentistry3000-808	130	8	pathogens	pathogen	NOUN
dentistry3000-808	130	9	contribute	contribute	VERB
dentistry3000-808	130	10	to	to	ADP
dentistry3000-808	130	11	ra	ra	PROPN
dentistry3000-808	130	12	may	may	AUX
dentistry3000-808	130	13	offer	offer	VERB
dentistry3000-808	130	14	new	new	ADJ
dentistry3000-808	130	15	avenues	avenue	NOUN
dentistry3000-808	130	16	for	for	ADP
dentistry3000-808	130	17	preventive	preventive	ADJ
dentistry3000-808	130	18	and	and	CCONJ
dentistry3000-808	130	19	therapeutic	therapeutic	ADJ
dentistry3000-808	130	20	strategies	strategy	NOUN
dentistry3000-808	130	21	,	,	PUNCT
dentistry3000-808	130	22	not	not	PART
dentistry3000-808	130	23	only	only	ADV
dentistry3000-808	130	24	targeting	target	VERB
dentistry3000-808	130	25	oral	oral	ADJ
dentistry3000-808	130	26	health	health	NOUN
dentistry3000-808	130	27	but	but	CCONJ
dentistry3000-808	130	28	also	also	ADV
dentistry3000-808	130	29	the	the	DET
dentistry3000-808	130	30	systemic	systemic	ADJ
dentistry3000-808	130	31	inflammatory	inflammatory	ADJ
dentistry3000-808	130	32	pathways	pathway	NOUN
dentistry3000-808	130	33	involved	involve	VERB
dentistry3000-808	130	34	in	in	ADP
dentistry3000-808	130	35	autoimmune	autoimmune	ADJ
dentistry3000-808	130	36	diseases	disease	NOUN
dentistry3000-808	130	37	like	like	ADP
dentistry3000-808	130	38	ra	ra	PROPN
dentistry3000-808	130	39	.	.	PUNCT
dentistry3000-808	131	1	integrating	integrate	VERB
dentistry3000-808	131	2	periodontal	periodontal	ADJ
dentistry3000-808	131	3	care	care	NOUN
dentistry3000-808	131	4	into	into	ADP
dentistry3000-808	131	5	the	the	DET
dentistry3000-808	131	6	management	management	NOUN
dentistry3000-808	131	7	of	of	ADP
dentistry3000-808	131	8	ra	ra	PROPN
dentistry3000-808	131	9	could	could	AUX
dentistry3000-808	131	10	potentially	potentially	ADV
dentistry3000-808	131	11	improve	improve	VERB
dentistry3000-808	131	12	patient	patient	ADJ
dentistry3000-808	131	13	outcomes	outcome	NOUN
dentistry3000-808	131	14	and	and	CCONJ
dentistry3000-808	131	15	reduce	reduce	VERB
dentistry3000-808	131	16	disease	disease	NOUN
dentistry3000-808	131	17	severity	severity	NOUN
dentistry3000-808	131	18	,	,	PUNCT
dentistry3000-808	131	19	highlighting	highlight	VERB
dentistry3000-808	131	20	the	the	DET
dentistry3000-808	131	21	importance	importance	NOUN
dentistry3000-808	131	22	of	of	ADP
dentistry3000-808	131	23	early	early	ADJ
dentistry3000-808	131	24	detection	detection	NOUN
dentistry3000-808	131	25	and	and	CCONJ
dentistry3000-808	131	26	poten&al	poten&al	PROPN
dentistry3000-808	131	27	role	role	NOUN
dentistry3000-808	131	28	of	of	ADP
dentistry3000-808	131	29	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	131	30	in	in	ADP
dentistry3000-808	131	31	rheumatoid	rheumatoid	NOUN
dentistry3000-808	131	32	arthri&s	arthri&s	PROPN
dentistry3000-808	131	33	vol	vol	NOUN
dentistry3000-808	131	34	13	13	NUM
dentistry3000-808	131	35	no	no	DET
dentistry3000-808	131	36	1	1	NUM
dentistry3000-808	131	37	(	(	PUNCT
dentistry3000-808	131	38	2025	2025	NUM
dentistry3000-808	131	39	)	)	PUNCT
dentistry3000-808	131	40	doi	doi	NOUN
dentistry3000-808	131	41	10.5195	10.5195	NUM
dentistry3000-808	131	42	/	/	SYM
dentistry3000-808	131	43	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	131	44	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	131	45	comprehensive	comprehensive	ADJ
dentistry3000-808	131	46	treatment	treatment	NOUN
dentistry3000-808	131	47	strategies	strategy	NOUN
dentistry3000-808	131	48	that	that	PRON
dentistry3000-808	131	49	address	address	VERB
dentistry3000-808	131	50	both	both	CCONJ
dentistry3000-808	131	51	oral	oral	ADJ
dentistry3000-808	131	52	and	and	CCONJ
dentistry3000-808	131	53	systemic	systemic	ADJ
dentistry3000-808	131	54	health	health	NOUN
dentistry3000-808	131	55	.	.	PUNCT
dentistry3000-808	132	1	funding	fund	VERB
dentistry3000-808	132	2	self	self	NOUN
dentistry3000-808	132	3	-	-	PUNCT
dentistry3000-808	132	4	funded	fund	VERB
dentistry3000-808	132	5	.	.	PUNCT
dentistry3000-808	133	1	conflict	conflict	NOUN
dentistry3000-808	133	2	of	of	ADP
dentistry3000-808	133	3	interest	interest	NOUN
dentistry3000-808	133	4	the	the	DET
dentistry3000-808	133	5	authors	author	NOUN
dentistry3000-808	133	6	declare	declare	VERB
dentistry3000-808	133	7	no	no	DET
dentistry3000-808	133	8	conflict	conflict	NOUN
dentistry3000-808	133	9	of	of	ADP
dentistry3000-808	133	10	interest	interest	NOUN
dentistry3000-808	133	11	.	.	PUNCT
dentistry3000-808	134	1	references	reference	NOUN
dentistry3000-808	134	2	1	1	NUM
dentistry3000-808	134	3	.	.	PUNCT
dentistry3000-808	134	4	martínez	martínez	NOUN
dentistry3000-808	134	5	-	-	PUNCT
dentistry3000-808	134	6	garcía	garcía	PROPN
dentistry3000-808	134	7	m	m	PROPN
dentistry3000-808	134	8	,	,	PUNCT
dentistry3000-808	134	9	hernández	hernández	PROPN
dentistry3000-808	134	10	-	-	PUNCT
dentistry3000-808	134	11	lemus	lemus	PROPN
dentistry3000-808	134	12	e.	e.	PROPN
dentistry3000-808	134	13	periodontal	periodontal	PROPN
dentistry3000-808	134	14	inflammation	inflammation	NOUN
dentistry3000-808	134	15	and	and	CCONJ
dentistry3000-808	134	16	systemic	systemic	ADJ
dentistry3000-808	134	17	diseases	disease	NOUN
dentistry3000-808	134	18	:	:	PUNCT
dentistry3000-808	134	19	an	an	DET
dentistry3000-808	134	20	overview	overview	NOUN
dentistry3000-808	134	21	.	.	PUNCT
dentistry3000-808	135	1	frontiers	frontier	NOUN
dentistry3000-808	135	2	in	in	ADP
dentistry3000-808	135	3	physiology	physiology	NOUN
dentistry3000-808	135	4	.	.	PUNCT
dentistry3000-808	136	1	2021	2021	NUM
dentistry3000-808	136	2	oct	oct	PROPN
dentistry3000-808	136	3	27;12:709438	27;12:709438	NUM
dentistry3000-808	136	4	.	.	PROPN
dentistry3000-808	137	1	2	2	NUM
dentistry3000-808	137	2	.	.	X
dentistry3000-808	137	3	jahid	jahid	PROPN
dentistry3000-808	137	4	m	m	PROPN
dentistry3000-808	137	5	,	,	PUNCT
dentistry3000-808	137	6	khan	khan	PROPN
dentistry3000-808	137	7	ku	ku	PROPN
dentistry3000-808	137	8	,	,	PUNCT
dentistry3000-808	137	9	ahmed	ahmed	PROPN
dentistry3000-808	137	10	rs	rs	PROPN
dentistry3000-808	137	11	.	.	PUNCT
dentistry3000-808	138	1	overview	overview	NOUN
dentistry3000-808	138	2	of	of	ADP
dentistry3000-808	138	3	rheumatoid	rheumatoid	NOUN
dentistry3000-808	138	4	arthritis	arthritis	NOUN
dentistry3000-808	138	5	and	and	CCONJ
dentistry3000-808	138	6	scientific	scientific	ADJ
dentistry3000-808	138	7	understanding	understanding	NOUN
dentistry3000-808	138	8	of	of	ADP
dentistry3000-808	138	9	the	the	DET
dentistry3000-808	138	10	disease	disease	NOUN
dentistry3000-808	138	11	.	.	PUNCT
dentistry3000-808	139	1	mediterranean	mediterranean	PROPN
dentistry3000-808	139	2	journal	journal	PROPN
dentistry3000-808	139	3	of	of	ADP
dentistry3000-808	139	4	rheumatology	rheumatology	NOUN
dentistry3000-808	139	5	.	.	PUNCT
dentistry3000-808	140	1	2023;34(3):284	2023;34(3):284	NUM
dentistry3000-808	140	2	-	-	SYM
dentistry3000-808	140	3	91	91	NUM
dentistry3000-808	140	4	.	.	PUNCT
dentistry3000-808	141	1	3	3	X
dentistry3000-808	141	2	.	.	X
dentistry3000-808	141	3	lopez	lopez	PROPN
dentistry3000-808	141	4	-	-	PUNCT
dentistry3000-808	141	5	oliva	oliva	PROPN
dentistry3000-808	141	6	i	i	PROPN
dentistry3000-808	141	7	,	,	PUNCT
dentistry3000-808	141	8	malcolm	malcolm	PROPN
dentistry3000-808	141	9	j	j	PROPN
dentistry3000-808	141	10	,	,	PUNCT
dentistry3000-808	141	11	culshaw	culshaw	PROPN
dentistry3000-808	141	12	s.	s.	PROPN
dentistry3000-808	141	13	periodontitis	periodontitis	PROPN
dentistry3000-808	141	14	and	and	CCONJ
dentistry3000-808	141	15	rheumatoid	rheumatoid	VERB
dentistry3000-808	141	16	arthritis	arthritis	NOUN
dentistry3000-808	141	17	—	—	PUNCT
dentistry3000-808	141	18	global	global	ADJ
dentistry3000-808	141	19	efforts	effort	NOUN
dentistry3000-808	141	20	to	to	PART
dentistry3000-808	141	21	untangle	untangle	VERB
dentistry3000-808	141	22	two	two	NUM
dentistry3000-808	141	23	complex	complex	ADJ
dentistry3000-808	141	24	diseases	disease	NOUN
dentistry3000-808	141	25	.	.	PUNCT
dentistry3000-808	142	1	periodontology	periodontology	NOUN
dentistry3000-808	142	2	2000	2000	NUM
dentistry3000-808	142	3	.	.	PUNCT
dentistry3000-808	143	1	2024	2024	NUM
dentistry3000-808	143	2	feb	feb	NOUN
dentistry3000-808	143	3	27	27	NUM
dentistry3000-808	143	4	.	.	PUNCT
dentistry3000-808	143	5	4	4	X
dentistry3000-808	143	6	.	.	X
dentistry3000-808	143	7	abdullah	abdullah	PROPN
dentistry3000-808	143	8	wl	wl	PROPN
dentistry3000-808	143	9	,	,	PUNCT
dentistry3000-808	143	10	al	al	PROPN
dentistry3000-808	143	11	-	-	PUNCT
dentistry3000-808	143	12	hashimy	hashimy	PROPN
dentistry3000-808	143	13	af	af	PROPN
dentistry3000-808	143	14	,	,	PUNCT
dentistry3000-808	143	15	al	al	PROPN
dentistry3000-808	143	16	-	-	PUNCT
dentistry3000-808	143	17	ghurabi	ghurabi	PROPN
dentistry3000-808	143	18	bh	bh	PROPN
dentistry3000-808	143	19	.	.	PROPN
dentistry3000-808	143	20	role	role	NOUN
dentistry3000-808	143	21	of	of	ADP
dentistry3000-808	143	22	salivary	salivary	ADJ
dentistry3000-808	143	23	caspase-1	caspase-1	NOUN
dentistry3000-808	143	24	and	and	CCONJ
dentistry3000-808	143	25	gasdermin	gasdermin	PROPN
dentistry3000-808	143	26	d	d	PROPN
dentistry3000-808	143	27	in	in	ADP
dentistry3000-808	143	28	the	the	DET
dentistry3000-808	143	29	pathophysiology	pathophysiology	NOUN
dentistry3000-808	143	30	of	of	ADP
dentistry3000-808	143	31	rheumatoid	rheumatoid	NOUN
dentistry3000-808	143	32	arthritis	arthritis	NOUN
dentistry3000-808	143	33	in	in	ADP
dentistry3000-808	143	34	relation	relation	NOUN
dentistry3000-808	143	35	to	to	PART
dentistry3000-808	143	36	salivary	salivary	VERB
dentistry3000-808	143	37	ph	ph	ADJ
dentistry3000-808	143	38	and	and	CCONJ
dentistry3000-808	143	39	flow	flow	NOUN
dentistry3000-808	143	40	rate	rate	NOUN
dentistry3000-808	143	41	of	of	ADP
dentistry3000-808	143	42	saliva	saliva	NOUN
dentistry3000-808	143	43	.	.	PUNCT
dentistry3000-808	144	1	world	world	PROPN
dentistry3000-808	144	2	academy	academy	PROPN
dentistry3000-808	144	3	of	of	ADP
dentistry3000-808	144	4	sciences	sciences	PROPN
dentistry3000-808	144	5	journal	journal	NOUN
dentistry3000-808	144	6	.	.	PUNCT
dentistry3000-808	145	1	2024	2024	NUM
dentistry3000-808	145	2	nov	nov	PROPN
dentistry3000-808	145	3	18;7(1):7	18;7(1):7	NUM
dentistry3000-808	145	4	.	.	PUNCT
dentistry3000-808	146	1	5	5	NUM
dentistry3000-808	146	2	.	.	X
dentistry3000-808	146	3	al	al	PROPN
dentistry3000-808	146	4	-	-	PUNCT
dentistry3000-808	146	5	daragi	daragi	PROPN
dentistry3000-808	146	6	fz	fz	PROPN
dentistry3000-808	146	7	,	,	PUNCT
dentistry3000-808	146	8	al	al	PROPN
dentistry3000-808	146	9	-	-	PUNCT
dentistry3000-808	146	10	ghurabi	ghurabi	PROPN
dentistry3000-808	146	11	bh	bh	PROPN
dentistry3000-808	146	12	,	,	PUNCT
dentistry3000-808	146	13	abdullah	abdullah	PROPN
dentistry3000-808	146	14	nn	nn	PROPN
dentistry3000-808	146	15	.	.	PROPN
dentistry3000-808	146	16	serum	serum	PROPN
dentistry3000-808	146	17	levels	level	NOUN
dentistry3000-808	146	18	of	of	ADP
dentistry3000-808	146	19	antimicrobial	antimicrobial	ADJ
dentistry3000-808	146	20	peptides	peptide	NOUN
dentistry3000-808	146	21	(	(	PUNCT
dentistry3000-808	146	22	cathelicidins	cathelicidin	NOUN
dentistry3000-808	146	23	and	and	CCONJ
dentistry3000-808	146	24	beta	beta	NOUN
dentistry3000-808	146	25	defensins-1	defensins-1	PROPN
dentistry3000-808	146	26	)	)	PUNCT
dentistry3000-808	146	27	in	in	ADP
dentistry3000-808	146	28	patients	patient	NOUN
dentistry3000-808	146	29	with	with	ADP
dentistry3000-808	146	30	periodontitis	periodontitis	NOUN
dentistry3000-808	146	31	.	.	PUNCT
dentistry3000-808	147	1	journal	journal	PROPN
dentistry3000-808	147	2	of	of	ADP
dentistry3000-808	147	3	baghdad	baghdad	PROPN
dentistry3000-808	147	4	college	college	PROPN
dentistry3000-808	147	5	of	of	ADP
dentistry3000-808	147	6	dentistry	dentistry	NOUN
dentistry3000-808	147	7	.	.	PUNCT
dentistry3000-808	148	1	2024	2024	NUM
dentistry3000-808	148	2	mar	mar	PROPN
dentistry3000-808	148	3	15;36(1):9	15;36(1):9	PROPN
dentistry3000-808	148	4	-	-	SYM
dentistry3000-808	148	5	18	18	NUM
dentistry3000-808	148	6	.	.	NOUN
dentistry3000-808	148	7	6	6	NUM
dentistry3000-808	148	8	.	.	X
dentistry3000-808	148	9	jain	jain	PROPN
dentistry3000-808	148	10	n	n	CCONJ
dentistry3000-808	148	11	,	,	PUNCT
dentistry3000-808	148	12	dutt	dutt	PROPN
dentistry3000-808	148	13	u	u	PROPN
dentistry3000-808	148	14	,	,	PUNCT
dentistry3000-808	148	15	radenkov	radenkov	PROPN
dentistry3000-808	148	16	i	i	PROPN
dentistry3000-808	148	17	,	,	PUNCT
dentistry3000-808	148	18	jain	jain	PROPN
dentistry3000-808	148	19	s.	s.	PROPN
dentistry3000-808	148	20	who	who	PRON
dentistry3000-808	148	21	's	be	AUX
dentistry3000-808	148	22	global	global	ADJ
dentistry3000-808	148	23	oral	oral	ADJ
dentistry3000-808	148	24	health	health	NOUN
dentistry3000-808	148	25	status	status	NOUN
dentistry3000-808	148	26	report	report	VERB
dentistry3000-808	148	27	2022	2022	NUM
dentistry3000-808	148	28	:	:	PUNCT
dentistry3000-808	148	29	actions	action	NOUN
dentistry3000-808	148	30	,	,	PUNCT
dentistry3000-808	148	31	discussion	discussion	NOUN
dentistry3000-808	148	32	and	and	CCONJ
dentistry3000-808	148	33	implementation	implementation	NOUN
dentistry3000-808	148	34	.	.	PUNCT
dentistry3000-808	149	1	oral	oral	ADJ
dentistry3000-808	149	2	diseases	disease	NOUN
dentistry3000-808	149	3	.	.	PUNCT
dentistry3000-808	150	1	2024	2024	NUM
dentistry3000-808	150	2	mar;30(2):73	mar;30(2):73	PROPN
dentistry3000-808	150	3	-	-	PUNCT
dentistry3000-808	150	4	9	9	NUM
dentistry3000-808	150	5	.	.	NOUN
dentistry3000-808	150	6	7	7	NUM
dentistry3000-808	150	7	.	.	X
dentistry3000-808	150	8	chen	chen	PROPN
dentistry3000-808	150	9	mx	mx	PROPN
dentistry3000-808	150	10	,	,	PUNCT
dentistry3000-808	150	11	zhong	zhong	PROPN
dentistry3000-808	150	12	yj	yj	PROPN
dentistry3000-808	150	13	,	,	PUNCT
dentistry3000-808	150	14	dong	dong	PROPN
dentistry3000-808	150	15	qq	qq	PROPN
dentistry3000-808	150	16	,	,	PUNCT
dentistry3000-808	150	17	wong	wong	PROPN
dentistry3000-808	150	18	hm	hm	PROPN
dentistry3000-808	150	19	,	,	PUNCT
dentistry3000-808	150	20	wen	wen	PROPN
dentistry3000-808	150	21	yf	yf	PROPN
dentistry3000-808	150	22	.	.	PUNCT
dentistry3000-808	150	23	global	global	ADJ
dentistry3000-808	150	24	,	,	PUNCT
dentistry3000-808	150	25	regional	regional	ADJ
dentistry3000-808	150	26	,	,	PUNCT
dentistry3000-808	150	27	and	and	CCONJ
dentistry3000-808	150	28	national	national	ADJ
dentistry3000-808	150	29	burden	burden	NOUN
dentistry3000-808	150	30	of	of	ADP
dentistry3000-808	150	31	severe	severe	ADJ
dentistry3000-808	150	32	periodontitis	periodontitis	NOUN
dentistry3000-808	150	33	,	,	PUNCT
dentistry3000-808	150	34	1990–2019	1990–2019	NUM
dentistry3000-808	150	35	:	:	PUNCT
dentistry3000-808	150	36	an	an	DET
dentistry3000-808	150	37	analysis	analysis	NOUN
dentistry3000-808	150	38	of	of	ADP
dentistry3000-808	150	39	the	the	DET
dentistry3000-808	150	40	global	global	ADJ
dentistry3000-808	150	41	burden	burden	NOUN
dentistry3000-808	150	42	of	of	ADP
dentistry3000-808	150	43	disease	disease	NOUN
dentistry3000-808	150	44	study	study	NOUN
dentistry3000-808	150	45	2019	2019	NUM
dentistry3000-808	150	46	.	.	PUNCT
dentistry3000-808	151	1	journal	journal	NOUN
dentistry3000-808	151	2	of	of	ADP
dentistry3000-808	151	3	clinical	clinical	ADJ
dentistry3000-808	151	4	periodontology	periodontology	NOUN
dentistry3000-808	151	5	.	.	PUNCT
dentistry3000-808	152	1	2021	2021	NUM
dentistry3000-808	152	2	sep;48(9):1165	sep;48(9):1165	VERB
dentistry3000-808	152	3	-	-	PUNCT
dentistry3000-808	152	4	88	88	NUM
dentistry3000-808	152	5	.	.	PUNCT
dentistry3000-808	152	6	8	8	NUM
dentistry3000-808	152	7	.	.	PUNCT
dentistry3000-808	152	8	kwon	kwon	PROPN
dentistry3000-808	152	9	t	t	PROPN
dentistry3000-808	152	10	,	,	PUNCT
dentistry3000-808	152	11	lamster	lamster	NOUN
dentistry3000-808	152	12	ib	ib	PROPN
dentistry3000-808	152	13	,	,	PUNCT
dentistry3000-808	152	14	levin	levin	PROPN
dentistry3000-808	152	15	l.	l.	PROPN
dentistry3000-808	152	16	current	current	PROPN
dentistry3000-808	152	17	concepts	concept	NOUN
dentistry3000-808	152	18	in	in	ADP
dentistry3000-808	152	19	the	the	DET
dentistry3000-808	152	20	management	management	NOUN
dentistry3000-808	152	21	of	of	ADP
dentistry3000-808	152	22	periodontitis	periodontitis	NOUN
dentistry3000-808	152	23	.	.	PUNCT
dentistry3000-808	153	1	international	international	ADJ
dentistry3000-808	153	2	dental	dental	ADJ
dentistry3000-808	153	3	journal	journal	NOUN
dentistry3000-808	153	4	.	.	PUNCT
dentistry3000-808	154	1	2021	2021	NUM
dentistry3000-808	154	2	dec	dec	PROPN
dentistry3000-808	154	3	1;71(6):462	1;71(6):462	NUM
dentistry3000-808	154	4	-	-	SYM
dentistry3000-808	154	5	76	76	NUM
dentistry3000-808	154	6	.	.	PUNCT
dentistry3000-808	154	7	9	9	X
dentistry3000-808	154	8	.	.	X
dentistry3000-808	154	9	al	al	PROPN
dentistry3000-808	154	10	-	-	PUNCT
dentistry3000-808	154	11	ghurabi	ghurabi	PROPN
dentistry3000-808	154	12	bh	bh	PROPN
dentistry3000-808	154	13	,	,	PUNCT
dentistry3000-808	154	14	adham	adham	PROPN
dentistry3000-808	154	15	zs	zs	PROPN
dentistry3000-808	154	16	,	,	PUNCT
dentistry3000-808	154	17	abbas	abbas	PROPN
dentistry3000-808	154	18	aa	aa	NOUN
dentistry3000-808	154	19	:	:	PUNCT
dentistry3000-808	154	20	level	level	NOUN
dentistry3000-808	154	21	of	of	ADP
dentistry3000-808	154	22	βdefensin	βdefensin	NOUN
dentistry3000-808	154	23	among	among	ADP
dentistry3000-808	154	24	iraqi	iraqi	ADJ
dentistry3000-808	154	25	patients	patient	NOUN
dentistry3000-808	154	26	with	with	ADP
dentistry3000-808	154	27	covid-19	covid-19	PROPN
dentistry3000-808	154	28	in	in	ADP
dentistry3000-808	154	29	relation	relation	NOUN
dentistry3000-808	154	30	to	to	ADP
dentistry3000-808	154	31	oral	oral	ADJ
dentistry3000-808	154	32	health	health	NOUN
dentistry3000-808	154	33	status	status	NOUN
dentistry3000-808	154	34	.	.	PUNCT
dentistry3000-808	155	1	j	j	PROPN
dentistry3000-808	155	2	emerg	emerg	PROPN
dentistry3000-808	155	3	med	med	PROPN
dentistry3000-808	155	4	trauma	trauma	PROPN
dentistry3000-808	155	5	acute	acute	PROPN
dentistry3000-808	155	6	care	care	NOUN
dentistry3000-808	155	7	.	.	PUNCT
dentistry3000-808	156	1	2022	2022	NUM
dentistry3000-808	156	2	;	;	PUNCT
dentistry3000-808	156	3	2022(3	2022(3	NUM
dentistry3000-808	156	4	):	):	PUNCT
dentistry3000-808	156	5	2	2	NUM
dentistry3000-808	156	6	.	.	NOUN
dentistry3000-808	156	7	10	10	NUM
dentistry3000-808	156	8	.	.	PUNCT
dentistry3000-808	157	1	al	al	PROPN
dentistry3000-808	157	2	-	-	PUNCT
dentistry3000-808	157	3	ghurabi	ghurabi	PROPN
dentistry3000-808	157	4	bh	bh	PROPN
dentistry3000-808	157	5	.	.	PUNCT
dentistry3000-808	158	1	the	the	DET
dentistry3000-808	158	2	role	role	NOUN
dentistry3000-808	158	3	of	of	ADP
dentistry3000-808	158	4	soluble	soluble	ADJ
dentistry3000-808	158	5	tlr-2	tlr-2	PUNCT
dentistry3000-808	158	6	in	in	ADP
dentistry3000-808	158	7	the	the	DET
dentistry3000-808	158	8	immunopathogenesis	immunopathogenesis	NOUN
dentistry3000-808	158	9	of	of	ADP
dentistry3000-808	158	10	gingivitis	gingivitis	NOUN
dentistry3000-808	158	11	.	.	PUNCT
dentistry3000-808	159	1	international	international	ADJ
dentistry3000-808	159	2	medical	medical	ADJ
dentistry3000-808	159	3	journal	journal	NOUN
dentistry3000-808	159	4	.	.	PUNCT
dentistry3000-808	160	1	2021	2021	NUM
dentistry3000-808	160	2	jun	jun	PROPN
dentistry3000-808	160	3	2;28(1):37	2;28(1):37	NUM
dentistry3000-808	160	4	-	-	SYM
dentistry3000-808	160	5	9	9	NUM
dentistry3000-808	160	6	.	.	NOUN
dentistry3000-808	160	7	11	11	NUM
dentistry3000-808	160	8	.	.	X
dentistry3000-808	160	9	krishna	krishna	PROPN
dentistry3000-808	160	10	as	as	ADP
dentistry3000-808	160	11	,	,	PUNCT
dentistry3000-808	160	12	ahalya	ahalya	ADJ
dentistry3000-808	160	13	u	u	NOUN
dentistry3000-808	160	14	,	,	PUNCT
dentistry3000-808	160	15	dharan	dharan	VERB
dentistry3000-808	160	16	ss	ss	PROPN
dentistry3000-808	160	17	,	,	PUNCT
dentistry3000-808	160	18	amal	amal	PROPN
dentistry3000-808	160	19	a.	a.	PROPN
dentistry3000-808	160	20	unraveling	unravel	VERB
dentistry3000-808	160	21	the	the	DET
dentistry3000-808	160	22	interplay	interplay	NOUN
dentistry3000-808	160	23	:	:	PUNCT
dentistry3000-808	160	24	periodontitis	periodontitis	NOUN
dentistry3000-808	160	25	and	and	CCONJ
dentistry3000-808	160	26	rheumatoid	rheumatoid	VERB
dentistry3000-808	160	27	arthritis	arthritis	NOUN
dentistry3000-808	160	28	.	.	PUNCT
dentistry3000-808	161	1	international	international	ADJ
dentistry3000-808	161	2	journal	journal	PROPN
dentistry3000-808	161	3	of	of	ADP
dentistry3000-808	161	4	tropical	tropical	ADJ
dentistry3000-808	161	5	medicines	medicine	NOUN
dentistry3000-808	161	6	.	.	PUNCT
dentistry3000-808	162	1	2024;1(1):31	2024;1(1):31	NUM
dentistry3000-808	162	2	-	-	SYM
dentistry3000-808	162	3	9p	9p	NUM
dentistry3000-808	162	4	12	12	NUM
dentistry3000-808	162	5	.	.	PUNCT
dentistry3000-808	163	1	mahmood	mahmood	PROPN
dentistry3000-808	163	2	hk	hk	PROPN
dentistry3000-808	163	3	,	,	PUNCT
dentistry3000-808	163	4	al	al	PROPN
dentistry3000-808	163	5	-	-	PUNCT
dentistry3000-808	163	6	ghurabi	ghurabi	PROPN
dentistry3000-808	163	7	bh	bh	PROPN
dentistry3000-808	163	8	.	.	PROPN
dentistry3000-808	163	9	association	association	PROPN
dentistry3000-808	163	10	between	between	ADP
dentistry3000-808	163	11	anti	anti	ADJ
dentistry3000-808	163	12	-	-	ADJ
dentistry3000-808	163	13	cmv	cmv	ADJ
dentistry3000-808	163	14	igg	igg	PROPN
dentistry3000-808	163	15	and	and	CCONJ
dentistry3000-808	163	16	salivary	salivary	ADJ
dentistry3000-808	163	17	levels	level	NOUN
dentistry3000-808	163	18	of	of	ADP
dentistry3000-808	163	19	il-6	il-6	NUM
dentistry3000-808	163	20	and	and	CCONJ
dentistry3000-808	163	21	tnf	tnf	PROPN
dentistry3000-808	163	22	-	-	PUNCT
dentistry3000-808	163	23	α	α	PROPN
dentistry3000-808	163	24	in	in	ADP
dentistry3000-808	163	25	chronic	chronic	ADJ
dentistry3000-808	163	26	periodontitis	periodontitis	NOUN
dentistry3000-808	163	27	.	.	PUNCT
dentistry3000-808	164	1	j	j	PROPN
dentistry3000-808	164	2	bagh	bagh	PROPN
dentistry3000-808	164	3	coll	coll	PROPN
dentistry3000-808	164	4	dent	dent	PROPN
dentistry3000-808	164	5	.	.	PUNCT
dentistry3000-808	165	1	2020;32(2):5	2020;32(2):5	NUM
dentistry3000-808	165	2	-	-	SYM
dentistry3000-808	165	3	11	11	NUM
dentistry3000-808	165	4	.	.	PUNCT
dentistry3000-808	166	1	13	13	NUM
dentistry3000-808	166	2	.	.	PUNCT
dentistry3000-808	167	1	li	li	PROPN
dentistry3000-808	167	2	x	x	PROPN
dentistry3000-808	167	3	,	,	PUNCT
dentistry3000-808	167	4	yu	yu	PROPN
dentistry3000-808	167	5	c	c	PROPN
dentistry3000-808	167	6	,	,	PUNCT
dentistry3000-808	167	7	zhang	zhang	PROPN
dentistry3000-808	167	8	b	b	PROPN
dentistry3000-808	167	9	,	,	PUNCT
dentistry3000-808	167	10	shan	shan	ADJ
dentistry3000-808	167	11	x	x	PROPN
dentistry3000-808	167	12	,	,	PUNCT
dentistry3000-808	167	13	mao	mao	PROPN
dentistry3000-808	167	14	w	w	PROPN
dentistry3000-808	167	15	,	,	PUNCT
dentistry3000-808	167	16	zhang	zhang	PROPN
dentistry3000-808	167	17	z	z	PROPN
dentistry3000-808	167	18	,	,	PUNCT
dentistry3000-808	167	19	wang	wang	PROPN
dentistry3000-808	167	20	c	c	PROPN
dentistry3000-808	167	21	,	,	PUNCT
dentistry3000-808	167	22	jin	jin	NOUN
dentistry3000-808	167	23	x	x	X
dentistry3000-808	167	24	,	,	PUNCT
dentistry3000-808	167	25	wang	wang	PROPN
dentistry3000-808	167	26	j	j	PROPN
dentistry3000-808	167	27	,	,	PUNCT
dentistry3000-808	167	28	zhao	zhao	PROPN
dentistry3000-808	167	29	h.	h.	PROPN
dentistry3000-808	167	30	the	the	DET
dentistry3000-808	167	31	recovery	recovery	NOUN
dentistry3000-808	167	32	of	of	ADP
dentistry3000-808	167	33	the	the	DET
dentistry3000-808	167	34	microbial	microbial	ADJ
dentistry3000-808	167	35	community	community	NOUN
dentistry3000-808	167	36	after	after	ADP
dentistry3000-808	167	37	plaque	plaque	NOUN
dentistry3000-808	167	38	poten&al	poten&al	PROPN
dentistry3000-808	167	39	role	role	NOUN
dentistry3000-808	167	40	of	of	ADP
dentistry3000-808	167	41	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	167	42	in	in	ADP
dentistry3000-808	167	43	rheumatoid	rheumatoid	NOUN
dentistry3000-808	167	44	arthri&s	arthri&s	PROPN
dentistry3000-808	167	45	vol	vol	NOUN
dentistry3000-808	167	46	13	13	NUM
dentistry3000-808	167	47	no	no	DET
dentistry3000-808	167	48	1	1	NUM
dentistry3000-808	167	49	(	(	PUNCT
dentistry3000-808	167	50	2025	2025	NUM
dentistry3000-808	167	51	)	)	PUNCT
dentistry3000-808	167	52	doi	doi	NOUN
dentistry3000-808	167	53	10.5195	10.5195	NUM
dentistry3000-808	167	54	/	/	SYM
dentistry3000-808	167	55	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	167	56	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	167	57	removal	removal	NOUN
dentistry3000-808	167	58	depends	depend	VERB
dentistry3000-808	167	59	on	on	ADP
dentistry3000-808	167	60	periodontal	periodontal	ADJ
dentistry3000-808	167	61	health	health	NOUN
dentistry3000-808	167	62	status	status	NOUN
dentistry3000-808	167	63	.	.	PUNCT
dentistry3000-808	168	1	npj	npj	PROPN
dentistry3000-808	168	2	biofilms	biofilm	NOUN
dentistry3000-808	168	3	and	and	CCONJ
dentistry3000-808	168	4	microbiomes	microbiomes	PROPN
dentistry3000-808	168	5	.	.	PROPN
dentistry3000-808	168	6	2023	2023	NUM
dentistry3000-808	168	7	oct	oct	NOUN
dentistry3000-808	168	8	7;9(1):75	7;9(1):75	NUM
dentistry3000-808	168	9	.	.	PUNCT
dentistry3000-808	169	1	14	14	NUM
dentistry3000-808	169	2	.	.	PUNCT
dentistry3000-808	169	3	di	di	NOUN
dentistry3000-808	169	4	spirito	spirito	PROPN
dentistry3000-808	169	5	f	f	PROPN
dentistry3000-808	169	6	,	,	PUNCT
dentistry3000-808	169	7	di	di	PROPN
dentistry3000-808	169	8	palo	palo	PROPN
dentistry3000-808	169	9	mp	mp	PROPN
dentistry3000-808	169	10	,	,	PUNCT
dentistry3000-808	169	11	rupe	rupe	X
dentistry3000-808	169	12	a	a	PRON
dentistry3000-808	169	13	,	,	PUNCT
dentistry3000-808	169	14	piedepalumbo	piedepalumbo	ADJ
dentistry3000-808	169	15	f	f	NOUN
dentistry3000-808	169	16	,	,	PUNCT
dentistry3000-808	169	17	sessa	sessa	ADJ
dentistry3000-808	169	18	a	a	PRON
dentistry3000-808	169	19	,	,	PUNCT
dentistry3000-808	169	20	de	de	X
dentistry3000-808	169	21	benedetto	benedetto	PROPN
dentistry3000-808	169	22	g	g	PROPN
dentistry3000-808	169	23	,	,	PUNCT
dentistry3000-808	169	24	russo	russo	PROPN
dentistry3000-808	169	25	barone	barone	PROPN
dentistry3000-808	169	26	s	s	PROPN
dentistry3000-808	169	27	,	,	PUNCT
dentistry3000-808	169	28	contaldo	contaldo	VERB
dentistry3000-808	169	29	m.	m.	NOUN
dentistry3000-808	169	30	periodontitis	periodontitis	NOUN
dentistry3000-808	169	31	in	in	ADP
dentistry3000-808	169	32	psoriatic	psoriatic	ADJ
dentistry3000-808	169	33	patients	patient	NOUN
dentistry3000-808	169	34	:	:	PUNCT
dentistry3000-808	169	35	epidemiological	epidemiological	ADJ
dentistry3000-808	169	36	insights	insight	NOUN
dentistry3000-808	169	37	and	and	CCONJ
dentistry3000-808	169	38	putative	putative	ADJ
dentistry3000-808	169	39	etiopathogenic	etiopathogenic	ADJ
dentistry3000-808	169	40	links	link	NOUN
dentistry3000-808	169	41	.	.	PUNCT
dentistry3000-808	170	1	epidemiologia	epidemiologia	NOUN
dentistry3000-808	170	2	.	.	PUNCT
dentistry3000-808	171	1	2024	2024	NUM
dentistry3000-808	171	2	jul	jul	PROPN
dentistry3000-808	171	3	26;5(3):479	26;5(3):479	NUM
dentistry3000-808	171	4	-	-	SYM
dentistry3000-808	171	5	98	98	NUM
dentistry3000-808	171	6	.	.	PUNCT
dentistry3000-808	171	7	15	15	NUM
dentistry3000-808	171	8	.	.	PUNCT
dentistry3000-808	172	1	gao	gao	PROPN
dentistry3000-808	172	2	l	l	PROPN
dentistry3000-808	172	3	,	,	PUNCT
dentistry3000-808	172	4	kang	kang	PROPN
dentistry3000-808	172	5	m	m	PROPN
dentistry3000-808	172	6	,	,	PUNCT
dentistry3000-808	172	7	zhang	zhang	PROPN
dentistry3000-808	172	8	mj	mj	PROPN
dentistry3000-808	172	9	,	,	PUNCT
dentistry3000-808	172	10	reza	reza	PROPN
dentistry3000-808	172	11	sailani	sailani	PROPN
dentistry3000-808	172	12	m	m	PROPN
dentistry3000-808	172	13	,	,	PUNCT
dentistry3000-808	172	14	kuraji	kuraji	PROPN
dentistry3000-808	172	15	r	r	PROPN
dentistry3000-808	172	16	,	,	PUNCT
dentistry3000-808	172	17	martinez	martinez	PROPN
dentistry3000-808	172	18	a	a	X
dentistry3000-808	172	19	,	,	PUNCT
dentistry3000-808	172	20	ye	ye	PRON
dentistry3000-808	172	21	c	c	NOUN
dentistry3000-808	172	22	,	,	PUNCT
dentistry3000-808	172	23	kamarajan	kamarajan	VERB
dentistry3000-808	172	24	p	p	PRON
dentistry3000-808	172	25	,	,	PUNCT
dentistry3000-808	172	26	le	le	X
dentistry3000-808	172	27	c	c	X
dentistry3000-808	172	28	,	,	PUNCT
dentistry3000-808	172	29	zhan	zhan	PROPN
dentistry3000-808	172	30	l	l	PROPN
dentistry3000-808	172	31	,	,	PUNCT
dentistry3000-808	172	32	rangé	rangé	NOUN
dentistry3000-808	172	33	h.	h.	PROPN
dentistry3000-808	172	34	polymicrobial	polymicrobial	ADJ
dentistry3000-808	172	35	periodontal	periodontal	ADJ
dentistry3000-808	172	36	disease	disease	NOUN
dentistry3000-808	172	37	triggers	trigger	VERB
dentistry3000-808	172	38	a	a	DET
dentistry3000-808	172	39	wide	wide	ADJ
dentistry3000-808	172	40	radius	radius	NOUN
dentistry3000-808	172	41	of	of	ADP
dentistry3000-808	172	42	effect	effect	NOUN
dentistry3000-808	172	43	and	and	CCONJ
dentistry3000-808	172	44	unique	unique	ADJ
dentistry3000-808	172	45	virome	virome	NOUN
dentistry3000-808	172	46	.	.	PUNCT
dentistry3000-808	173	1	npj	npj	PROPN
dentistry3000-808	173	2	biofilms	biofilm	NOUN
dentistry3000-808	173	3	and	and	CCONJ
dentistry3000-808	173	4	microbiomes	microbiomes	PROPN
dentistry3000-808	173	5	.	.	PROPN
dentistry3000-808	173	6	2020	2020	NUM
dentistry3000-808	173	7	mar	mar	PROPN
dentistry3000-808	173	8	10;6(1):10	10;6(1):10	NUM
dentistry3000-808	173	9	.	.	PUNCT
dentistry3000-808	174	1	16	16	NUM
dentistry3000-808	174	2	.	.	PUNCT
dentistry3000-808	174	3	krutyhołowa	krutyhołowa	PROPN
dentistry3000-808	174	4	a	a	PRON
dentistry3000-808	174	5	,	,	PUNCT
dentistry3000-808	174	6	strzelec	strzelec	PROPN
dentistry3000-808	174	7	k	k	NOUN
dentistry3000-808	174	8	,	,	PUNCT
dentistry3000-808	174	9	dziedzic	dziedzic	PROPN
dentistry3000-808	174	10	a	a	PRON
dentistry3000-808	174	11	,	,	PUNCT
dentistry3000-808	174	12	bereta	bereta	PROPN
dentistry3000-808	174	13	gp	gp	PROPN
dentistry3000-808	174	14	,	,	PUNCT
dentistry3000-808	174	15	łazarz	łazarz	NOUN
dentistry3000-808	174	16	-	-	PUNCT
dentistry3000-808	174	17	bartyzel	bartyzel	NOUN
dentistry3000-808	174	18	k	k	PROPN
dentistry3000-808	174	19	,	,	PUNCT
dentistry3000-808	174	20	potempa	potempa	PROPN
dentistry3000-808	174	21	j	j	PROPN
dentistry3000-808	174	22	,	,	PUNCT
dentistry3000-808	174	23	gawron	gawron	PROPN
dentistry3000-808	174	24	k.	k.	PROPN
dentistry3000-808	174	25	host	host	PROPN
dentistry3000-808	174	26	and	and	CCONJ
dentistry3000-808	174	27	bacterial	bacterial	ADJ
dentistry3000-808	174	28	factors	factor	NOUN
dentistry3000-808	174	29	linking	link	VERB
dentistry3000-808	174	30	periodontitis	periodontitis	NOUN
dentistry3000-808	174	31	and	and	CCONJ
dentistry3000-808	174	32	rheumatoid	rheumatoid	VERB
dentistry3000-808	174	33	arthritis	arthritis	NOUN
dentistry3000-808	174	34	.	.	PUNCT
dentistry3000-808	175	1	frontiers	frontier	NOUN
dentistry3000-808	175	2	in	in	ADP
dentistry3000-808	175	3	immunology	immunology	NOUN
dentistry3000-808	175	4	.	.	PUNCT
dentistry3000-808	176	1	2022	2022	NUM
dentistry3000-808	176	2	aug	aug	PROPN
dentistry3000-808	176	3	25;13:980805	25;13:980805	NUM
dentistry3000-808	176	4	.	.	PUNCT
dentistry3000-808	176	5	17	17	NUM
dentistry3000-808	176	6	.	.	PUNCT
dentistry3000-808	177	1	xu	xu	PROPN
dentistry3000-808	178	1	w	w	PROPN
dentistry3000-808	178	2	,	,	PUNCT
dentistry3000-808	178	3	zhou	zhou	PROPN
dentistry3000-808	178	4	w	w	PROPN
dentistry3000-808	178	5	,	,	PUNCT
dentistry3000-808	178	6	wang	wang	PROPN
dentistry3000-808	178	7	h	h	PROPN
dentistry3000-808	178	8	,	,	PUNCT
dentistry3000-808	178	9	liang	liang	PROPN
dentistry3000-808	178	10	s.	s.	PROPN
dentistry3000-808	178	11	roles	role	NOUN
dentistry3000-808	178	12	of	of	ADP
dentistry3000-808	178	13	porphyromonas	porphyromona	NOUN
dentistry3000-808	178	14	gingivalis	gingivalis	PROPN
dentistry3000-808	178	15	and	and	CCONJ
dentistry3000-808	178	16	its	its	PRON
dentistry3000-808	178	17	virulence	virulence	NOUN
dentistry3000-808	178	18	factors	factor	NOUN
dentistry3000-808	178	19	in	in	ADP
dentistry3000-808	178	20	periodontitis	periodontitis	NOUN
dentistry3000-808	178	21	.	.	PUNCT
dentistry3000-808	179	1	advances	advance	NOUN
dentistry3000-808	179	2	in	in	ADP
dentistry3000-808	179	3	protein	protein	NOUN
dentistry3000-808	179	4	chemistry	chemistry	NOUN
dentistry3000-808	179	5	and	and	CCONJ
dentistry3000-808	179	6	structural	structural	ADJ
dentistry3000-808	179	7	biology	biology	NOUN
dentistry3000-808	179	8	.	.	PUNCT
dentistry3000-808	180	1	2020	2020	NUM
dentistry3000-808	180	2	jan	jan	PROPN
dentistry3000-808	180	3	1;120:45	1;120:45	PROPN
dentistry3000-808	180	4	-	-	PUNCT
dentistry3000-808	180	5	84	84	NUM
dentistry3000-808	180	6	.	.	PUNCT
dentistry3000-808	181	1	18	18	NUM
dentistry3000-808	181	2	.	.	NOUN
dentistry3000-808	181	3	aleksijević	aleksijević	PROPN
dentistry3000-808	181	4	lh	lh	PROPN
dentistry3000-808	181	5	,	,	PUNCT
dentistry3000-808	181	6	aleksijević	aleksijević	PROPN
dentistry3000-808	181	7	m	m	PROPN
dentistry3000-808	181	8	,	,	PUNCT
dentistry3000-808	181	9	škrlec	škrlec	PROPN
dentistry3000-808	182	1	i	i	PROPN
dentistry3000-808	182	2	,	,	PUNCT
dentistry3000-808	182	3	šram	šram	PROPN
dentistry3000-808	182	4	m	m	PROPN
dentistry3000-808	182	5	,	,	PUNCT
dentistry3000-808	182	6	šram	šram	PROPN
dentistry3000-808	182	7	m	m	PROPN
dentistry3000-808	182	8	,	,	PUNCT
dentistry3000-808	182	9	talapko	talapko	PROPN
dentistry3000-808	182	10	j.	j.	PROPN
dentistry3000-808	182	11	porphyromonas	porphyromonas	PROPN
dentistry3000-808	182	12	gingivalis	gingivalis	VERB
dentistry3000-808	182	13	virulence	virulence	NOUN
dentistry3000-808	182	14	factors	factor	NOUN
dentistry3000-808	182	15	and	and	CCONJ
dentistry3000-808	182	16	clinical	clinical	ADJ
dentistry3000-808	182	17	significance	significance	NOUN
dentistry3000-808	182	18	in	in	ADP
dentistry3000-808	182	19	periodontal	periodontal	ADJ
dentistry3000-808	182	20	disease	disease	NOUN
dentistry3000-808	182	21	and	and	CCONJ
dentistry3000-808	182	22	coronary	coronary	ADJ
dentistry3000-808	182	23	artery	artery	NOUN
dentistry3000-808	182	24	diseases	disease	NOUN
dentistry3000-808	182	25	.	.	PUNCT
dentistry3000-808	183	1	pathogens	pathogen	NOUN
dentistry3000-808	183	2	.	.	PUNCT
dentistry3000-808	184	1	2022	2022	NUM
dentistry3000-808	184	2	oct	oct	PROPN
dentistry3000-808	184	3	11;11(10):1173	11;11(10):1173	NUM
dentistry3000-808	184	4	.	.	PROPN
dentistry3000-808	185	1	19	19	NUM
dentistry3000-808	185	2	.	.	PUNCT
dentistry3000-808	186	1	huang	huang	PROPN
dentistry3000-808	186	2	x	x	PROPN
dentistry3000-808	186	3	,	,	PUNCT
dentistry3000-808	186	4	li	li	PROPN
dentistry3000-808	186	5	y	y	PROPN
dentistry3000-808	186	6	,	,	PUNCT
dentistry3000-808	186	7	zhang	zhang	PROPN
dentistry3000-808	186	8	j	j	PROPN
dentistry3000-808	186	9	,	,	PUNCT
dentistry3000-808	186	10	feng	feng	PROPN
dentistry3000-808	186	11	q.	q.	PROPN
dentistry3000-808	186	12	linking	link	VERB
dentistry3000-808	186	13	periodontitis	periodontitis	NOUN
dentistry3000-808	186	14	with	with	ADP
dentistry3000-808	186	15	inflammatory	inflammatory	ADJ
dentistry3000-808	186	16	bowel	bowel	NOUN
dentistry3000-808	186	17	disease	disease	NOUN
dentistry3000-808	186	18	through	through	ADP
dentistry3000-808	186	19	the	the	DET
dentistry3000-808	186	20	oral	oral	ADJ
dentistry3000-808	186	21	–	–	PUNCT
dentistry3000-808	186	22	gut	gut	NOUN
dentistry3000-808	186	23	axis	axis	NOUN
dentistry3000-808	186	24	:	:	PUNCT
dentistry3000-808	186	25	the	the	DET
dentistry3000-808	186	26	potential	potential	ADJ
dentistry3000-808	186	27	role	role	NOUN
dentistry3000-808	186	28	of	of	ADP
dentistry3000-808	186	29	porphyromonas	porphyromonas	PROPN
dentistry3000-808	186	30	gingivalis	gingivalis	PROPN
dentistry3000-808	186	31	.	.	PUNCT
dentistry3000-808	187	1	biomedicines	biomedicines	PROPN
dentistry3000-808	187	2	.	.	PUNCT
dentistry3000-808	188	1	2024	2024	NUM
dentistry3000-808	188	2	mar	mar	PROPN
dentistry3000-808	188	3	19;12(3):685	19;12(3):685	NUM
dentistry3000-808	188	4	.	.	PUNCT
dentistry3000-808	188	5	20	20	NUM
dentistry3000-808	188	6	.	.	PUNCT
dentistry3000-808	189	1	zhou	zhou	PROPN
dentistry3000-808	189	2	n	n	CCONJ
dentistry3000-808	189	3	,	,	PUNCT
dentistry3000-808	189	4	zou	zou	PROPN
dentistry3000-808	189	5	f	f	PROPN
dentistry3000-808	189	6	,	,	PUNCT
dentistry3000-808	189	7	cheng	cheng	PROPN
dentistry3000-808	189	8	x	x	PROPN
dentistry3000-808	189	9	,	,	PUNCT
dentistry3000-808	189	10	huang	huang	PROPN
dentistry3000-808	189	11	y	y	PROPN
dentistry3000-808	189	12	,	,	PUNCT
dentistry3000-808	189	13	zou	zou	PROPN
dentistry3000-808	189	14	h	h	PROPN
dentistry3000-808	189	15	,	,	PUNCT
dentistry3000-808	189	16	niu	niu	PROPN
dentistry3000-808	189	17	q	q	PROPN
dentistry3000-808	189	18	,	,	PUNCT
dentistry3000-808	189	19	qiu	qiu	PROPN
dentistry3000-808	189	20	y	y	PROPN
dentistry3000-808	189	21	,	,	PUNCT
dentistry3000-808	189	22	shan	shan	PROPN
dentistry3000-808	189	23	f	f	PROPN
dentistry3000-808	189	24	,	,	PUNCT
dentistry3000-808	189	25	luo	luo	PROPN
dentistry3000-808	189	26	a	a	PROPN
dentistry3000-808	189	27	,	,	PUNCT
dentistry3000-808	189	28	teng	teng	PROPN
dentistry3000-808	189	29	w	w	PROPN
dentistry3000-808	189	30	,	,	PUNCT
dentistry3000-808	189	31	sun	sun	PROPN
dentistry3000-808	189	32	j.	j.	PROPN
dentistry3000-808	189	33	porphyromonas	porphyromonas	PROPN
dentistry3000-808	189	34	gingivalis	gingivalis	PROPN
dentistry3000-808	189	35	induces	induce	VERB
dentistry3000-808	189	36	periodontitis	periodontitis	NOUN
dentistry3000-808	189	37	,	,	PUNCT
dentistry3000-808	189	38	causes	cause	VERB
dentistry3000-808	189	39	immune	immune	ADJ
dentistry3000-808	189	40	imbalance	imbalance	NOUN
dentistry3000-808	189	41	,	,	PUNCT
dentistry3000-808	189	42	and	and	CCONJ
dentistry3000-808	189	43	promotes	promote	VERB
dentistry3000-808	189	44	rheumatoid	rheumatoid	VERB
dentistry3000-808	189	45	arthritis	arthritis	NOUN
dentistry3000-808	189	46	.	.	PUNCT
dentistry3000-808	190	1	journal	journal	NOUN
dentistry3000-808	190	2	of	of	ADP
dentistry3000-808	190	3	leukocyte	leukocyte	NOUN
dentistry3000-808	190	4	biology	biology	NOUN
dentistry3000-808	190	5	.	.	PUNCT
dentistry3000-808	191	1	2021	2021	NUM
dentistry3000-808	191	2	sep;110(3):461	sep;110(3):461	NOUN
dentistry3000-808	191	3	-	-	SYM
dentistry3000-808	191	4	73	73	NUM
dentistry3000-808	191	5	.	.	PUNCT
dentistry3000-808	192	1	21	21	NUM
dentistry3000-808	192	2	.	.	PUNCT
dentistry3000-808	193	1	zheng	zheng	PROPN
dentistry3000-808	193	2	s	s	PROPN
dentistry3000-808	193	3	,	,	PUNCT
dentistry3000-808	193	4	yu	yu	PROPN
dentistry3000-808	193	5	s	s	PROPN
dentistry3000-808	193	6	,	,	PUNCT
dentistry3000-808	193	7	fan	fan	PROPN
dentistry3000-808	193	8	x	x	PROPN
dentistry3000-808	193	9	,	,	PUNCT
dentistry3000-808	193	10	zhang	zhang	PROPN
dentistry3000-808	193	11	y	y	PROPN
dentistry3000-808	193	12	,	,	PUNCT
dentistry3000-808	193	13	sun	sun	PROPN
dentistry3000-808	193	14	y	y	PROPN
dentistry3000-808	193	15	,	,	PUNCT
dentistry3000-808	193	16	lin	lin	PROPN
dentistry3000-808	193	17	l	l	PROPN
dentistry3000-808	193	18	,	,	PUNCT
dentistry3000-808	193	19	wang	wang	PROPN
dentistry3000-808	193	20	h	h	PROPN
dentistry3000-808	193	21	,	,	PUNCT
dentistry3000-808	193	22	pan	pan	PROPN
dentistry3000-808	193	23	y	y	PROPN
dentistry3000-808	193	24	,	,	PUNCT
dentistry3000-808	193	25	li	li	PROPN
dentistry3000-808	193	26	c.	c.	PROPN
dentistry3000-808	193	27	porphyromonas	porphyromonas	PROPN
dentistry3000-808	193	28	gingivalis	gingivali	VERB
dentistry3000-808	193	29	survival	survival	NOUN
dentistry3000-808	193	30	skills	skill	NOUN
dentistry3000-808	193	31	:	:	PUNCT
dentistry3000-808	193	32	immune	immune	ADJ
dentistry3000-808	193	33	evasion	evasion	NOUN
dentistry3000-808	193	34	.	.	PUNCT
dentistry3000-808	194	1	journal	journal	NOUN
dentistry3000-808	194	2	of	of	ADP
dentistry3000-808	194	3	periodontal	periodontal	ADJ
dentistry3000-808	194	4	research	research	NOUN
dentistry3000-808	194	5	.	.	PUNCT
dentistry3000-808	195	1	2021	2021	NUM
dentistry3000-808	195	2	dec;56(6):1007	dec;56(6):1007	NOUN
dentistry3000-808	195	3	-	-	PUNCT
dentistry3000-808	195	4	18	18	NUM
dentistry3000-808	195	5	.	.	PUNCT
dentistry3000-808	195	6	22	22	NUM
dentistry3000-808	195	7	.	.	PUNCT
dentistry3000-808	196	1	kareem	kareem	PROPN
dentistry3000-808	196	2	hh	hh	PROPN
dentistry3000-808	196	3	,	,	PUNCT
dentistry3000-808	196	4	al	al	PROPN
dentistry3000-808	196	5	-	-	PUNCT
dentistry3000-808	196	6	ghurabi	ghurabi	PROPN
dentistry3000-808	196	7	bh	bh	PROPN
dentistry3000-808	196	8	,	,	PUNCT
dentistry3000-808	196	9	albadri	albadri	PROPN
dentistry3000-808	196	10	c.	c.	PROPN
dentistry3000-808	196	11	molecular	molecular	ADJ
dentistry3000-808	196	12	detection	detection	NOUN
dentistry3000-808	196	13	of	of	ADP
dentistry3000-808	196	14	porphyromonas	porphyromona	NOUN
dentistry3000-808	196	15	gingivalis	gingivali	VERB
dentistry3000-808	196	16	in	in	ADP
dentistry3000-808	196	17	covid-19	covid-19	PROPN
dentistry3000-808	196	18	patients	patient	NOUN
dentistry3000-808	196	19	.	.	PUNCT
dentistry3000-808	197	1	journal	journal	PROPN
dentistry3000-808	197	2	of	of	ADP
dentistry3000-808	197	3	baghdad	baghdad	PROPN
dentistry3000-808	197	4	college	college	PROPN
dentistry3000-808	197	5	of	of	ADP
dentistry3000-808	197	6	dentistry	dentistry	NOUN
dentistry3000-808	197	7	.	.	PUNCT
dentistry3000-808	198	1	2022	2022	NUM
dentistry3000-808	198	2	jun	jun	PROPN
dentistry3000-808	198	3	15;34(2):52	15;34(2):52	PROPN
dentistry3000-808	198	4	-	-	SYM
dentistry3000-808	198	5	61	61	NUM
dentistry3000-808	198	6	.	.	PUNCT
dentistry3000-808	198	7	23	23	NUM
dentistry3000-808	198	8	.	.	PUNCT
dentistry3000-808	199	1	neurath	neurath	PROPN
dentistry3000-808	199	2	n	n	CCONJ
dentistry3000-808	199	3	,	,	PUNCT
dentistry3000-808	199	4	kesting	kesting	NOUN
dentistry3000-808	199	5	m.	m.	NOUN
dentistry3000-808	199	6	cytokines	cytokine	NOUN
dentistry3000-808	199	7	in	in	ADP
dentistry3000-808	199	8	gingivitis	gingivitis	NOUN
dentistry3000-808	199	9	and	and	CCONJ
dentistry3000-808	199	10	periodontitis	periodontitis	NOUN
dentistry3000-808	199	11	:	:	PUNCT
dentistry3000-808	199	12	from	from	ADP
dentistry3000-808	199	13	pathogenesis	pathogenesis	NOUN
dentistry3000-808	199	14	to	to	ADP
dentistry3000-808	199	15	therapeutic	therapeutic	ADJ
dentistry3000-808	199	16	targets	target	NOUN
dentistry3000-808	199	17	.	.	PUNCT
dentistry3000-808	200	1	frontiers	frontier	NOUN
dentistry3000-808	200	2	in	in	ADP
dentistry3000-808	200	3	immunology	immunology	NOUN
dentistry3000-808	200	4	.	.	PUNCT
dentistry3000-808	201	1	2024	2024	NUM
dentistry3000-808	201	2	aug	aug	PROPN
dentistry3000-808	201	3	26;15:1435054	26;15:1435054	NUM
dentistry3000-808	201	4	.	.	PUNCT
dentistry3000-808	201	5	24	24	NUM
dentistry3000-808	201	6	.	.	PUNCT
dentistry3000-808	201	7	melgar	melgar	NOUN
dentistry3000-808	201	8	-	-	PUNCT
dentistry3000-808	201	9	rodríguez	rodríguez	NOUN
dentistry3000-808	201	10	s	s	PROPN
dentistry3000-808	201	11	,	,	PUNCT
dentistry3000-808	201	12	polanco	polanco	PROPN
dentistry3000-808	201	13	a	a	X
dentistry3000-808	201	14	,	,	PUNCT
dentistry3000-808	201	15	ríos	ríos	PROPN
dentistry3000-808	201	16	-	-	PUNCT
dentistry3000-808	201	17	muñoz	muñoz	PROPN
dentistry3000-808	201	18	j	j	PROPN
dentistry3000-808	201	19	,	,	PUNCT
dentistry3000-808	201	20	garcía	garcía	PROPN
dentistry3000-808	201	21	m	m	PROPN
dentistry3000-808	201	22	,	,	PUNCT
dentistry3000-808	201	23	sierra	sierra	PROPN
dentistry3000-808	201	24	-	-	PUNCT
dentistry3000-808	201	25	cristancho	cristancho	PROPN
dentistry3000-808	201	26	a	a	PRON
dentistry3000-808	201	27	,	,	PUNCT
dentistry3000-808	201	28	gonzález	gonzález	PROPN
dentistry3000-808	201	29	-	-	PUNCT
dentistry3000-808	201	30	osuna	osuna	PROPN
dentistry3000-808	201	31	l	l	PROPN
dentistry3000-808	201	32	,	,	PUNCT
dentistry3000-808	201	33	díazzúñiga	díazzúñiga	PROPN
dentistry3000-808	201	34	j	j	PROPN
dentistry3000-808	201	35	,	,	PUNCT
dentistry3000-808	201	36	carvajal	carvajal	VERB
dentistry3000-808	201	37	p	p	PRON
dentistry3000-808	201	38	,	,	PUNCT
dentistry3000-808	201	39	vernal	vernal	ADJ
dentistry3000-808	201	40	r	r	NOUN
dentistry3000-808	201	41	,	,	PUNCT
dentistry3000-808	201	42	bravo	bravo	PROPN
dentistry3000-808	201	43	d.	d.	PROPN
dentistry3000-808	201	44	differential	differential	PROPN
dentistry3000-808	201	45	response	response	NOUN
dentistry3000-808	201	46	of	of	ADP
dentistry3000-808	201	47	human	human	ADJ
dentistry3000-808	201	48	dendritic	dendritic	ADJ
dentistry3000-808	201	49	cells	cell	NOUN
dentistry3000-808	201	50	upon	upon	SCONJ
dentistry3000-808	201	51	stimulation	stimulation	NOUN
dentistry3000-808	201	52	with	with	ADP
dentistry3000-808	201	53	encapsulated	encapsulate	VERB
dentistry3000-808	201	54	or	or	CCONJ
dentistry3000-808	201	55	nonencapsulated	nonencapsulate	VERB
dentistry3000-808	201	56	isogenic	isogenic	ADJ
dentistry3000-808	201	57	strains	strain	NOUN
dentistry3000-808	201	58	of	of	ADP
dentistry3000-808	201	59	porphyromonas	porphyromona	NOUN
dentistry3000-808	201	60	gingivalis	gingivalis	PROPN
dentistry3000-808	201	61	.	.	PUNCT
dentistry3000-808	202	1	international	international	ADJ
dentistry3000-808	202	2	journal	journal	NOUN
dentistry3000-808	202	3	of	of	ADP
dentistry3000-808	202	4	molecular	molecular	ADJ
dentistry3000-808	202	5	sciences	science	NOUN
dentistry3000-808	202	6	.	.	PUNCT
dentistry3000-808	203	1	2024	2024	NUM
dentistry3000-808	203	2	apr	apr	PROPN
dentistry3000-808	203	3	20;25(8):4510	20;25(8):4510	NUM
dentistry3000-808	203	4	.	.	PUNCT
dentistry3000-808	204	1	25	25	NUM
dentistry3000-808	204	2	.	.	PUNCT
dentistry3000-808	205	1	chen	chen	PROPN
dentistry3000-808	205	2	wa	wa	PROPN
dentistry3000-808	205	3	,	,	PUNCT
dentistry3000-808	205	4	dou	dou	PROPN
dentistry3000-808	205	5	y	y	PROPN
dentistry3000-808	205	6	,	,	PUNCT
dentistry3000-808	205	7	fletcher	fletcher	PROPN
dentistry3000-808	205	8	hm	hm	PROPN
dentistry3000-808	205	9	,	,	PUNCT
dentistry3000-808	205	10	boskovic	boskovic	ADJ
dentistry3000-808	205	11	ds	ds	PROPN
dentistry3000-808	205	12	.	.	PROPN
dentistry3000-808	205	13	local	local	ADJ
dentistry3000-808	205	14	and	and	CCONJ
dentistry3000-808	205	15	systemic	systemic	ADJ
dentistry3000-808	205	16	effects	effect	NOUN
dentistry3000-808	205	17	of	of	ADP
dentistry3000-808	205	18	poten&al	poten&al	PROPN
dentistry3000-808	205	19	role	role	NOUN
dentistry3000-808	205	20	of	of	ADP
dentistry3000-808	205	21	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	205	22	in	in	ADP
dentistry3000-808	205	23	rheumatoid	rheumatoid	NOUN
dentistry3000-808	205	24	arthri&s	arthri&s	PROPN
dentistry3000-808	205	25	vol	vol	NOUN
dentistry3000-808	205	26	13	13	NUM
dentistry3000-808	205	27	no	no	DET
dentistry3000-808	205	28	1	1	NUM
dentistry3000-808	205	29	(	(	PUNCT
dentistry3000-808	205	30	2025	2025	NUM
dentistry3000-808	205	31	)	)	PUNCT
dentistry3000-808	205	32	doi	doi	NOUN
dentistry3000-808	205	33	10.5195	10.5195	NUM
dentistry3000-808	205	34	/	/	SYM
dentistry3000-808	205	35	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	205	36	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	205	37	porphyromonas	porphyromona	NOUN
dentistry3000-808	205	38	gingivalis	gingivali	VERB
dentistry3000-808	205	39	infection	infection	NOUN
dentistry3000-808	205	40	.	.	PUNCT
dentistry3000-808	206	1	microorganisms	microorganism	NOUN
dentistry3000-808	206	2	.	.	PUNCT
dentistry3000-808	207	1	2023	2023	NUM
dentistry3000-808	207	2	feb	feb	NOUN
dentistry3000-808	207	3	13;11(2):470	13;11(2):470	NUM
dentistry3000-808	207	4	.	.	PROPN
dentistry3000-808	207	5	26	26	NUM
dentistry3000-808	207	6	.	.	X
dentistry3000-808	207	7	ali	ali	PROPN
dentistry3000-808	207	8	,	,	PUNCT
dentistry3000-808	207	9	a.	a.	PROPN
dentistry3000-808	207	10	f.	f.	PROPN
dentistry3000-808	207	11	and	and	CCONJ
dentistry3000-808	207	12	taha	taha	PROPN
dentistry3000-808	207	13	,	,	PUNCT
dentistry3000-808	207	14	g.	g.	PROPN
dentistry3000-808	207	15	i.	i.	PROPN
dentistry3000-808	207	16	2024	2024	NUM
dentistry3000-808	207	17	.	.	PUNCT
dentistry3000-808	208	1	gingival	gingival	NOUN
dentistry3000-808	208	2	crevicular	crevicular	ADJ
dentistry3000-808	208	3	fluid	fluid	NOUN
dentistry3000-808	208	4	volume	volume	NOUN
dentistry3000-808	208	5	and	and	CCONJ
dentistry3000-808	208	6	protein	protein	NOUN
dentistry3000-808	208	7	concentration	concentration	NOUN
dentistry3000-808	208	8	:	:	PUNCT
dentistry3000-808	208	9	a	a	DET
dentistry3000-808	208	10	biomarker	biomarker	NOUN
dentistry3000-808	208	11	tool	tool	NOUN
dentistry3000-808	208	12	for	for	ADP
dentistry3000-808	208	13	predicting	predict	VERB
dentistry3000-808	208	14	periodontal	periodontal	ADJ
dentistry3000-808	208	15	diseases	disease	NOUN
dentistry3000-808	208	16	progression	progression	NOUN
dentistry3000-808	208	17	and	and	CCONJ
dentistry3000-808	208	18	severity	severity	NOUN
dentistry3000-808	208	19	.	.	PUNCT
dentistry3000-808	209	1	natural	natural	ADJ
dentistry3000-808	209	2	and	and	CCONJ
dentistry3000-808	209	3	life	life	NOUN
dentistry3000-808	209	4	sciences	science	NOUN
dentistry3000-808	209	5	communications.23(4	communications.23(4	NOUN
dentistry3000-808	209	6	):	):	PUNCT
dentistry3000-808	209	7	e2024055	e2024055	NOUN
dentistry3000-808	209	8	.	.	PUNCT
dentistry3000-808	210	1	27	27	NUM
dentistry3000-808	210	2	.	.	PUNCT
dentistry3000-808	211	1	figus	figus	PROPN
dentistry3000-808	211	2	fa	fa	PROPN
dentistry3000-808	211	3	,	,	PUNCT
dentistry3000-808	211	4	piga	piga	PROPN
dentistry3000-808	211	5	m	m	PROPN
dentistry3000-808	211	6	,	,	PUNCT
dentistry3000-808	211	7	azzolin	azzolin	PROPN
dentistry3000-808	211	8	i	i	PRON
dentistry3000-808	211	9	,	,	PUNCT
dentistry3000-808	211	10	mcconnell	mcconnell	PROPN
dentistry3000-808	211	11	r	r	PROPN
dentistry3000-808	211	12	,	,	PUNCT
dentistry3000-808	211	13	iagnocco	iagnocco	ADJ
dentistry3000-808	211	14	a.	a.	NOUN
dentistry3000-808	211	15	rheumatoid	rheumatoid	NOUN
dentistry3000-808	211	16	arthritis	arthritis	NOUN
dentistry3000-808	211	17	:	:	PUNCT
dentistry3000-808	211	18	extraarticular	extraarticular	ADJ
dentistry3000-808	211	19	manifestations	manifestation	NOUN
dentistry3000-808	211	20	and	and	CCONJ
dentistry3000-808	211	21	comorbidities	comorbiditie	NOUN
dentistry3000-808	211	22	.	.	PUNCT
dentistry3000-808	212	1	autoimmunity	autoimmunity	NOUN
dentistry3000-808	212	2	reviews	review	NOUN
dentistry3000-808	212	3	.	.	PUNCT
dentistry3000-808	213	1	2021	2021	NUM
dentistry3000-808	213	2	apr	apr	NOUN
dentistry3000-808	213	3	1;20(4):102776	1;20(4):102776	NUM
dentistry3000-808	213	4	.	.	PUNCT
dentistry3000-808	214	1	28	28	NUM
dentistry3000-808	214	2	.	.	PUNCT
dentistry3000-808	215	1	gonzález	gonzález	PROPN
dentistry3000-808	215	2	da	da	PROPN
dentistry3000-808	215	3	,	,	PUNCT
dentistry3000-808	215	4	bianchi	bianchi	NOUN
dentistry3000-808	215	5	ml	ml	PROPN
dentistry3000-808	215	6	,	,	PUNCT
dentistry3000-808	215	7	armada	armada	PROPN
dentistry3000-808	215	8	m	m	PROPN
dentistry3000-808	215	9	,	,	PUNCT
dentistry3000-808	215	10	escalante	escalante	PROPN
dentistry3000-808	215	11	ac	ac	PROPN
dentistry3000-808	215	12	,	,	PUNCT
dentistry3000-808	215	13	salgado	salgado	PROPN
dentistry3000-808	215	14	pa	pa	PROPN
dentistry3000-808	215	15	,	,	PUNCT
dentistry3000-808	215	16	seni	seni	PROPN
dentistry3000-808	215	17	s	s	PART
dentistry3000-808	215	18	,	,	PUNCT
dentistry3000-808	215	19	citera	citera	PROPN
dentistry3000-808	215	20	g	g	PROPN
dentistry3000-808	215	21	,	,	PUNCT
dentistry3000-808	215	22	ferrary	ferrary	ADJ
dentistry3000-808	215	23	t	t	PROPN
dentistry3000-808	215	24	,	,	PUNCT
dentistry3000-808	215	25	orman	orman	PROPN
dentistry3000-808	215	26	b.	b.	PROPN
dentistry3000-808	215	27	hyposalivation	hyposalivation	PROPN
dentistry3000-808	215	28	and	and	CCONJ
dentistry3000-808	215	29	periodontal	periodontal	ADJ
dentistry3000-808	215	30	disease	disease	NOUN
dentistry3000-808	215	31	as	as	ADP
dentistry3000-808	215	32	oral	oral	ADJ
dentistry3000-808	215	33	non	non	ADJ
dentistry3000-808	215	34	-	-	ADJ
dentistry3000-808	215	35	articular	articular	ADJ
dentistry3000-808	215	36	characteristics	characteristic	NOUN
dentistry3000-808	215	37	in	in	ADP
dentistry3000-808	215	38	rheumatoid	rheumatoid	NOUN
dentistry3000-808	215	39	arthritis	arthritis	NOUN
dentistry3000-808	215	40	.	.	PUNCT
dentistry3000-808	216	1	clinical	clinical	ADJ
dentistry3000-808	216	2	rheumatology	rheumatology	NOUN
dentistry3000-808	216	3	.	.	PUNCT
dentistry3000-808	217	1	2024	2024	NUM
dentistry3000-808	217	2	jan;43(1):95	jan;43(1):95	NOUN
dentistry3000-808	217	3	-	-	PUNCT
dentistry3000-808	217	4	102	102	NUM
dentistry3000-808	217	5	.	.	PUNCT
dentistry3000-808	217	6	29	29	NUM
dentistry3000-808	217	7	.	.	PUNCT
dentistry3000-808	217	8	benli	benli	PROPN
dentistry3000-808	217	9	m	m	PROPN
dentistry3000-808	217	10	,	,	PUNCT
dentistry3000-808	217	11	batool	batool	PROPN
dentistry3000-808	217	12	f	f	PROPN
dentistry3000-808	217	13	,	,	PUNCT
dentistry3000-808	217	14	stutz	stutz	PROPN
dentistry3000-808	217	15	c	c	NOUN
dentistry3000-808	217	16	,	,	PUNCT
dentistry3000-808	217	17	petit	petit	PROPN
dentistry3000-808	217	18	c	c	PROPN
dentistry3000-808	217	19	,	,	PUNCT
dentistry3000-808	217	20	jung	jung	PROPN
dentistry3000-808	217	21	s	s	PROPN
dentistry3000-808	217	22	,	,	PUNCT
dentistry3000-808	217	23	huck	huck	PROPN
dentistry3000-808	217	24	o.	o.	PROPN
dentistry3000-808	217	25	orofacial	orofacial	ADJ
dentistry3000-808	217	26	manifestations	manifestation	NOUN
dentistry3000-808	217	27	and	and	CCONJ
dentistry3000-808	217	28	dental	dental	ADJ
dentistry3000-808	217	29	management	management	NOUN
dentistry3000-808	217	30	of	of	ADP
dentistry3000-808	217	31	systemic	systemic	ADJ
dentistry3000-808	217	32	lupus	lupus	PROPN
dentistry3000-808	217	33	erythematosus	erythematosus	NOUN
dentistry3000-808	217	34	:	:	PUNCT
dentistry3000-808	217	35	a	a	DET
dentistry3000-808	217	36	review	review	NOUN
dentistry3000-808	217	37	.	.	PUNCT
dentistry3000-808	218	1	oral	oral	ADJ
dentistry3000-808	218	2	diseases	disease	NOUN
dentistry3000-808	218	3	.	.	PUNCT
dentistry3000-808	219	1	2021	2021	NUM
dentistry3000-808	219	2	mar;27(2):151	mar;27(2):151	NOUN
dentistry3000-808	219	3	-	-	PUNCT
dentistry3000-808	219	4	67	67	NUM
dentistry3000-808	219	5	.	.	PUNCT
dentistry3000-808	219	6	30	30	NUM
dentistry3000-808	219	7	.	.	PUNCT
dentistry3000-808	220	1	sokolova	sokolova	PROPN
dentistry3000-808	220	2	mv	mv	PROPN
dentistry3000-808	220	3	,	,	PUNCT
dentistry3000-808	220	4	schett	schett	PROPN
dentistry3000-808	220	5	g	g	PROPN
dentistry3000-808	220	6	,	,	PUNCT
dentistry3000-808	220	7	steffen	steffen	PROPN
dentistry3000-808	220	8	u.	u.	PROPN
dentistry3000-808	220	9	autoantibodies	autoantibody	NOUN
dentistry3000-808	220	10	in	in	ADP
dentistry3000-808	220	11	rheumatoid	rheumatoid	NOUN
dentistry3000-808	220	12	arthritis	arthritis	NOUN
dentistry3000-808	220	13	:	:	PUNCT
dentistry3000-808	220	14	historical	historical	ADJ
dentistry3000-808	220	15	background	background	NOUN
dentistry3000-808	220	16	and	and	CCONJ
dentistry3000-808	220	17	novel	novel	ADJ
dentistry3000-808	220	18	findings	finding	NOUN
dentistry3000-808	220	19	.	.	PUNCT
dentistry3000-808	221	1	clinical	clinical	ADJ
dentistry3000-808	221	2	reviews	review	NOUN
dentistry3000-808	221	3	in	in	ADP
dentistry3000-808	221	4	allergy	allergy	NOUN
dentistry3000-808	221	5	&	&	CCONJ
dentistry3000-808	221	6	immunology	immunology	NOUN
dentistry3000-808	221	7	.	.	PUNCT
dentistry3000-808	222	1	2022	2022	NUM
dentistry3000-808	222	2	oct;63(2):138	oct;63(2):138	PROPN
dentistry3000-808	222	3	-	-	PUNCT
dentistry3000-808	222	4	51	51	NUM
dentistry3000-808	222	5	.	.	PUNCT
dentistry3000-808	223	1	31	31	NUM
dentistry3000-808	223	2	.	.	PUNCT
dentistry3000-808	224	1	gao	gao	PROPN
dentistry3000-808	224	2	y	y	PROPN
dentistry3000-808	224	3	,	,	PUNCT
dentistry3000-808	224	4	zhang	zhang	PROPN
dentistry3000-808	224	5	y	y	PROPN
dentistry3000-808	224	6	,	,	PUNCT
dentistry3000-808	224	7	liu	liu	PROPN
dentistry3000-808	224	8	x.	x.	PROPN
dentistry3000-808	224	9	rheumatoid	rheumatoid	VERB
dentistry3000-808	224	10	arthritis	arthritis	NOUN
dentistry3000-808	224	11	:	:	PUNCT
dentistry3000-808	224	12	pathogenesis	pathogenesis	NOUN
dentistry3000-808	224	13	and	and	CCONJ
dentistry3000-808	224	14	therapeutic	therapeutic	ADJ
dentistry3000-808	224	15	advances	advance	NOUN
dentistry3000-808	224	16	.	.	PUNCT
dentistry3000-808	225	1	medcomm	medcomm	PROPN
dentistry3000-808	225	2	.	.	PUNCT
dentistry3000-808	226	1	2024	2024	NUM
dentistry3000-808	226	2	mar;5(3):e509	mar;5(3):e509	NOUN
dentistry3000-808	226	3	.	.	PUNCT
dentistry3000-808	227	1	32	32	NUM
dentistry3000-808	227	2	.	.	X
dentistry3000-808	228	1	ding	ding	PROPN
dentistry3000-808	228	2	q	q	PROPN
dentistry3000-808	228	3	,	,	PUNCT
dentistry3000-808	228	4	hu	hu	PROPN
dentistry3000-808	228	5	w	w	PROPN
dentistry3000-808	228	6	,	,	PUNCT
dentistry3000-808	228	7	wang	wang	PROPN
dentistry3000-808	228	8	r	r	PROPN
dentistry3000-808	228	9	,	,	PUNCT
dentistry3000-808	228	10	yang	yang	PROPN
dentistry3000-808	228	11	q	q	PROPN
dentistry3000-808	228	12	,	,	PUNCT
dentistry3000-808	228	13	zhu	zhu	PROPN
dentistry3000-808	228	14	m	m	PROPN
dentistry3000-808	228	15	,	,	PUNCT
dentistry3000-808	228	16	li	li	PROPN
dentistry3000-808	228	17	m	m	PROPN
dentistry3000-808	228	18	,	,	PUNCT
dentistry3000-808	228	19	cai	cai	PROPN
dentistry3000-808	228	20	j	j	PROPN
dentistry3000-808	228	21	,	,	PUNCT
dentistry3000-808	228	22	rose	rise	VERB
dentistry3000-808	228	23	p	p	PRON
dentistry3000-808	228	24	,	,	PUNCT
dentistry3000-808	228	25	mao	mao	PROPN
dentistry3000-808	228	26	j	j	PROPN
dentistry3000-808	228	27	,	,	PUNCT
dentistry3000-808	228	28	zhu	zhu	PROPN
dentistry3000-808	228	29	yz	yz	PROPN
dentistry3000-808	228	30	.	.	PUNCT
dentistry3000-808	229	1	signaling	signal	VERB
dentistry3000-808	229	2	pathways	pathway	NOUN
dentistry3000-808	229	3	in	in	ADP
dentistry3000-808	229	4	rheumatoid	rheumatoid	NOUN
dentistry3000-808	229	5	arthritis	arthritis	NOUN
dentistry3000-808	229	6	:	:	PUNCT
dentistry3000-808	229	7	implications	implication	NOUN
dentistry3000-808	229	8	for	for	ADP
dentistry3000-808	229	9	targeted	target	VERB
dentistry3000-808	229	10	therapy	therapy	NOUN
dentistry3000-808	229	11	.	.	PUNCT
dentistry3000-808	230	1	signal	signal	ADJ
dentistry3000-808	230	2	transduction	transduction	NOUN
dentistry3000-808	230	3	and	and	CCONJ
dentistry3000-808	230	4	targeted	target	VERB
dentistry3000-808	230	5	therapy	therapy	NOUN
dentistry3000-808	230	6	.	.	PUNCT
dentistry3000-808	231	1	2023	2023	NUM
dentistry3000-808	231	2	feb	feb	NOUN
dentistry3000-808	231	3	17;8(1):68	17;8(1):68	NUM
dentistry3000-808	231	4	.	.	PUNCT
dentistry3000-808	232	1	33	33	NUM
dentistry3000-808	232	2	.	.	PUNCT
dentistry3000-808	233	1	su	su	PROPN
dentistry3000-808	233	2	j	j	PROPN
dentistry3000-808	233	3	,	,	PUNCT
dentistry3000-808	233	4	li	li	PROPN
dentistry3000-808	233	5	s	s	PROPN
dentistry3000-808	233	6	,	,	PUNCT
dentistry3000-808	233	7	chen	chen	PROPN
dentistry3000-808	233	8	j	j	PROPN
dentistry3000-808	233	9	,	,	PUNCT
dentistry3000-808	233	10	jian	jian	PROPN
dentistry3000-808	233	11	c	c	PROPN
dentistry3000-808	233	12	,	,	PUNCT
dentistry3000-808	233	13	hu	hu	PROPN
dentistry3000-808	233	14	j	j	PROPN
dentistry3000-808	233	15	,	,	PUNCT
dentistry3000-808	233	16	du	du	PROPN
dentistry3000-808	233	17	h	h	PROPN
dentistry3000-808	233	18	,	,	PUNCT
dentistry3000-808	233	19	hai	hai	PROPN
dentistry3000-808	233	20	h	h	PROPN
dentistry3000-808	233	21	,	,	PUNCT
dentistry3000-808	233	22	wu	wu	PROPN
dentistry3000-808	233	23	j	j	PROPN
dentistry3000-808	233	24	,	,	PUNCT
dentistry3000-808	233	25	zeng	zeng	PROPN
dentistry3000-808	233	26	f	f	PROPN
dentistry3000-808	233	27	,	,	PUNCT
dentistry3000-808	233	28	zhu	zhu	PROPN
dentistry3000-808	233	29	j	j	PROPN
dentistry3000-808	233	30	,	,	PUNCT
dentistry3000-808	233	31	liu	liu	PROPN
dentistry3000-808	233	32	y.	y.	PROPN
dentistry3000-808	233	33	glycerophospholipid	glycerophospholipid	PROPN
dentistry3000-808	233	34	metabolism	metabolism	NOUN
dentistry3000-808	233	35	is	be	AUX
dentistry3000-808	233	36	involved	involve	VERB
dentistry3000-808	233	37	in	in	ADP
dentistry3000-808	233	38	rheumatoid	rheumatoid	VERB
dentistry3000-808	233	39	arthritis	arthritis	NOUN
dentistry3000-808	233	40	pathogenesis	pathogenesis	NOUN
dentistry3000-808	233	41	by	by	ADP
dentistry3000-808	233	42	regulating	regulate	VERB
dentistry3000-808	233	43	the	the	DET
dentistry3000-808	233	44	il-6	il-6	NUM
dentistry3000-808	233	45	/	/	SYM
dentistry3000-808	233	46	jak	jak	PROPN
dentistry3000-808	233	47	signaling	signal	VERB
dentistry3000-808	233	48	pathway	pathway	NOUN
dentistry3000-808	233	49	.	.	PUNCT
dentistry3000-808	234	1	biochemical	biochemical	ADJ
dentistry3000-808	234	2	and	and	CCONJ
dentistry3000-808	234	3	biophysical	biophysical	ADJ
dentistry3000-808	234	4	research	research	NOUN
dentistry3000-808	234	5	communications	communication	NOUN
dentistry3000-808	234	6	.	.	PUNCT
dentistry3000-808	235	1	2022	2022	NUM
dentistry3000-808	235	2	apr	apr	NOUN
dentistry3000-808	235	3	16;600:130	16;600:130	NUM
dentistry3000-808	235	4	-	-	SYM
dentistry3000-808	235	5	5	5	NUM
dentistry3000-808	235	6	.	.	PUNCT
dentistry3000-808	235	7	34	34	NUM
dentistry3000-808	235	8	.	.	PUNCT
dentistry3000-808	236	1	xiao	xiao	PROPN
dentistry3000-808	236	2	f	f	PROPN
dentistry3000-808	236	3	,	,	PUNCT
dentistry3000-808	236	4	li	li	PROPN
dentistry3000-808	236	5	c	c	PROPN
dentistry3000-808	236	6	,	,	PUNCT
dentistry3000-808	236	7	lin	lin	PROPN
dentistry3000-808	236	8	y	y	PROPN
dentistry3000-808	236	9	,	,	PUNCT
dentistry3000-808	236	10	peng	peng	PROPN
dentistry3000-808	236	11	z	z	PROPN
dentistry3000-808	236	12	,	,	PUNCT
dentistry3000-808	236	13	xu	xu	PROPN
dentistry3000-808	236	14	x	x	PROPN
dentistry3000-808	236	15	,	,	PUNCT
dentistry3000-808	236	16	wen	wen	PROPN
dentistry3000-808	236	17	y	y	PROPN
dentistry3000-808	236	18	,	,	PUNCT
dentistry3000-808	236	19	huang	huang	PROPN
dentistry3000-808	236	20	n	n	PROPN
dentistry3000-808	236	21	,	,	PUNCT
dentistry3000-808	236	22	zhang	zhang	PROPN
dentistry3000-808	236	23	p.	p.	PROPN
dentistry3000-808	236	24	increased	increase	VERB
dentistry3000-808	236	25	risk	risk	NOUN
dentistry3000-808	236	26	of	of	ADP
dentistry3000-808	236	27	periodontitis	periodontitis	NOUN
dentistry3000-808	236	28	occurrence	occurrence	NOUN
dentistry3000-808	236	29	in	in	ADP
dentistry3000-808	236	30	patients	patient	NOUN
dentistry3000-808	236	31	with	with	ADP
dentistry3000-808	236	32	rheumatoid	rheumatoid	NOUN
dentistry3000-808	236	33	arthritis	arthritis	NOUN
dentistry3000-808	236	34	and	and	CCONJ
dentistry3000-808	236	35	its	its	PRON
dentistry3000-808	236	36	association	association	NOUN
dentistry3000-808	236	37	with	with	ADP
dentistry3000-808	236	38	the	the	DET
dentistry3000-808	236	39	levels	level	NOUN
dentistry3000-808	236	40	of	of	ADP
dentistry3000-808	236	41	il-1β	il-1β	PROPN
dentistry3000-808	236	42	and	and	CCONJ
dentistry3000-808	236	43	tnf	tnf	PROPN
dentistry3000-808	236	44	-	-	PUNCT
dentistry3000-808	236	45	α	α	PROPN
dentistry3000-808	236	46	in	in	ADP
dentistry3000-808	236	47	gingival	gingival	NOUN
dentistry3000-808	236	48	crevicular	crevicular	ADJ
dentistry3000-808	236	49	fluid	fluid	NOUN
dentistry3000-808	236	50	.	.	PUNCT
dentistry3000-808	237	1	annals	annal	NOUN
dentistry3000-808	237	2	of	of	ADP
dentistry3000-808	237	3	palliative	palliative	ADJ
dentistry3000-808	237	4	medicine	medicine	NOUN
dentistry3000-808	237	5	.	.	PUNCT
dentistry3000-808	238	1	2021	2021	NUM
dentistry3000-808	239	1	aug;10(8):9078087	aug;10(8):9078087	PROPN
dentistry3000-808	239	2	-	-	PUNCT
dentistry3000-808	239	3	9087	9087	NUM
dentistry3000-808	239	4	.	.	PUNCT
dentistry3000-808	240	1	35	35	NUM
dentistry3000-808	240	2	.	.	PUNCT
dentistry3000-808	241	1	luo	luo	PROPN
dentistry3000-808	241	2	p	p	PROPN
dentistry3000-808	241	3	,	,	PUNCT
dentistry3000-808	241	4	wang	wang	PROPN
dentistry3000-808	241	5	p	p	PROPN
dentistry3000-808	241	6	,	,	PUNCT
dentistry3000-808	241	7	xu	xu	PROPN
dentistry3000-808	241	8	j	j	PROPN
dentistry3000-808	241	9	,	,	PUNCT
dentistry3000-808	241	10	hou	hou	PROPN
dentistry3000-808	241	11	w	w	PROPN
dentistry3000-808	241	12	,	,	PUNCT
dentistry3000-808	241	13	xu	xu	PROPN
dentistry3000-808	242	1	p	p	X
dentistry3000-808	242	2	,	,	PUNCT
dentistry3000-808	242	3	xu	xu	PROPN
dentistry3000-808	243	1	k	k	PROPN
dentistry3000-808	243	2	,	,	PUNCT
dentistry3000-808	243	3	liu	liu	PROPN
dentistry3000-808	243	4	l.	l.	PROPN
dentistry3000-808	243	5	immunomodulatory	immunomodulatory	PROPN
dentistry3000-808	243	6	role	role	NOUN
dentistry3000-808	243	7	of	of	ADP
dentistry3000-808	243	8	t	t	PROPN
dentistry3000-808	243	9	helper	helper	NOUN
dentistry3000-808	243	10	cells	cell	NOUN
dentistry3000-808	243	11	in	in	ADP
dentistry3000-808	243	12	rheumatoid	rheumatoid	NOUN
dentistry3000-808	243	13	arthritis	arthritis	NOUN
dentistry3000-808	243	14	:	:	PUNCT
dentistry3000-808	243	15	a	a	DET
dentistry3000-808	243	16	comprehensive	comprehensive	ADJ
dentistry3000-808	243	17	research	research	NOUN
dentistry3000-808	243	18	review	review	NOUN
dentistry3000-808	243	19	.	.	PUNCT
dentistry3000-808	244	1	bone	bone	NOUN
dentistry3000-808	244	2	&	&	CCONJ
dentistry3000-808	244	3	joint	joint	ADJ
dentistry3000-808	244	4	research	research	NOUN
dentistry3000-808	244	5	.	.	PUNCT
dentistry3000-808	245	1	2022	2022	NUM
dentistry3000-808	245	2	jul	jul	PROPN
dentistry3000-808	245	3	20;11(7):426	20;11(7):426	PROPN
dentistry3000-808	245	4	-	-	SYM
dentistry3000-808	245	5	38	38	NUM
dentistry3000-808	245	6	.	.	PUNCT
dentistry3000-808	246	1	36	36	NUM
dentistry3000-808	246	2	.	.	PUNCT
dentistry3000-808	247	1	renvert	renvert	PROPN
dentistry3000-808	247	2	s	s	PROPN
dentistry3000-808	247	3	,	,	PUNCT
dentistry3000-808	247	4	berglund	berglund	PROPN
dentistry3000-808	247	5	js	js	PROPN
dentistry3000-808	247	6	,	,	PUNCT
dentistry3000-808	247	7	persson	persson	PROPN
dentistry3000-808	247	8	gr	gr	PROPN
dentistry3000-808	247	9	,	,	PUNCT
dentistry3000-808	247	10	söderlin	söderlin	PROPN
dentistry3000-808	247	11	mk	mk	PROPN
dentistry3000-808	247	12	.	.	PUNCT
dentistry3000-808	248	1	the	the	DET
dentistry3000-808	248	2	association	association	NOUN
dentistry3000-808	248	3	between	between	ADP
dentistry3000-808	248	4	rheumatoid	rheumatoid	NOUN
dentistry3000-808	248	5	arthritis	arthritis	NOUN
dentistry3000-808	248	6	and	and	CCONJ
dentistry3000-808	248	7	periodontal	periodontal	ADJ
dentistry3000-808	248	8	disease	disease	NOUN
dentistry3000-808	248	9	in	in	ADP
dentistry3000-808	248	10	a	a	DET
dentistry3000-808	248	11	population	population	NOUN
dentistry3000-808	248	12	-	-	PUNCT
dentistry3000-808	248	13	based	base	VERB
dentistry3000-808	248	14	crosssectional	crosssectional	ADJ
dentistry3000-808	248	15	case	case	NOUN
dentistry3000-808	248	16	-	-	PUNCT
dentistry3000-808	248	17	control	control	NOUN
dentistry3000-808	248	18	study	study	NOUN
dentistry3000-808	248	19	.	.	PUNCT
dentistry3000-808	249	1	bmc	bmc	PROPN
dentistry3000-808	249	2	rheumatology	rheumatology	NOUN
dentistry3000-808	249	3	.	.	PUNCT
dentistry3000-808	250	1	2020	2020	NUM
dentistry3000-808	250	2	dec;4:1	dec;4:1	PROPN
dentistry3000-808	250	3	-	-	PUNCT
dentistry3000-808	250	4	8	8	NUM
dentistry3000-808	250	5	.	.	PUNCT
dentistry3000-808	251	1	37	37	NUM
dentistry3000-808	251	2	.	.	PUNCT
dentistry3000-808	252	1	li	li	PROPN
dentistry3000-808	252	2	y	y	PROPN
dentistry3000-808	252	3	,	,	PUNCT
dentistry3000-808	252	4	guo	guo	PROPN
dentistry3000-808	252	5	r	r	PROPN
dentistry3000-808	252	6	,	,	PUNCT
dentistry3000-808	252	7	oduro	oduro	NOUN
dentistry3000-808	252	8	pk	pk	PROPN
dentistry3000-808	252	9	,	,	PUNCT
dentistry3000-808	252	10	sun	sun	PROPN
dentistry3000-808	252	11	t	t	PROPN
dentistry3000-808	252	12	,	,	PUNCT
dentistry3000-808	252	13	chen	chen	PROPN
dentistry3000-808	252	14	h	h	PROPN
dentistry3000-808	252	15	,	,	PUNCT
dentistry3000-808	252	16	yi	yi	PROPN
dentistry3000-808	252	17	y	y	PROPN
dentistry3000-808	252	18	,	,	PUNCT
dentistry3000-808	252	19	zeng	zeng	PROPN
dentistry3000-808	252	20	w	w	PROPN
dentistry3000-808	252	21	,	,	PUNCT
dentistry3000-808	252	22	wang	wang	PROPN
dentistry3000-808	252	23	q	q	PROPN
dentistry3000-808	252	24	,	,	PUNCT
dentistry3000-808	252	25	leng	leng	PROPN
dentistry3000-808	252	26	l	l	PROPN
dentistry3000-808	252	27	,	,	PUNCT
dentistry3000-808	252	28	yang	yang	PROPN
dentistry3000-808	252	29	l	l	PROPN
dentistry3000-808	252	30	,	,	PUNCT
dentistry3000-808	252	31	zhang	zhang	PROPN
dentistry3000-808	252	32	j.	j.	PROPN
dentistry3000-808	252	33	the	the	DET
dentistry3000-808	252	34	relationship	relationship	NOUN
dentistry3000-808	252	35	between	between	ADP
dentistry3000-808	252	36	porphyromonas	porphyromona	NOUN
dentistry3000-808	252	37	gingivalis	gingivalis	PROPN
dentistry3000-808	252	38	and	and	CCONJ
dentistry3000-808	252	39	rheumatoid	rheumatoid	VERB
dentistry3000-808	252	40	arthritis	arthritis	NOUN
dentistry3000-808	252	41	:	:	PUNCT
dentistry3000-808	252	42	a	a	DET
dentistry3000-808	252	43	meta	meta	ADJ
dentistry3000-808	252	44	-	-	PUNCT
dentistry3000-808	252	45	analysis	analysis	NOUN
dentistry3000-808	252	46	.	.	PUNCT
dentistry3000-808	253	1	frontiers	frontier	NOUN
dentistry3000-808	253	2	in	in	ADP
dentistry3000-808	253	3	cellular	cellular	ADJ
dentistry3000-808	253	4	and	and	CCONJ
dentistry3000-808	253	5	infection	infection	NOUN
dentistry3000-808	253	6	microbiology	microbiology	NOUN
dentistry3000-808	253	7	.	.	PUNCT
dentistry3000-808	254	1	2022	2022	NUM
dentistry3000-808	254	2	jul	jul	PROPN
dentistry3000-808	254	3	18;12:956417	18;12:956417	NUM
dentistry3000-808	254	4	.	.	PUNCT
dentistry3000-808	255	1	poten&al	poten&al	PRON
dentistry3000-808	255	2	role	role	NOUN
dentistry3000-808	255	3	of	of	ADP
dentistry3000-808	255	4	periodontopathogens	periodontopathogen	NOUN
dentistry3000-808	255	5	in	in	ADP
dentistry3000-808	255	6	rheumatoid	rheumatoid	NOUN
dentistry3000-808	255	7	arthri&s	arthri&s	PROPN
dentistry3000-808	255	8	vol	vol	NOUN
dentistry3000-808	255	9	13	13	NUM
dentistry3000-808	255	10	no	no	DET
dentistry3000-808	255	11	1	1	NUM
dentistry3000-808	255	12	(	(	PUNCT
dentistry3000-808	255	13	2025	2025	NUM
dentistry3000-808	255	14	)	)	PUNCT
dentistry3000-808	255	15	doi	doi	NOUN
dentistry3000-808	255	16	10.5195	10.5195	NUM
dentistry3000-808	255	17	/	/	SYM
dentistry3000-808	255	18	d3000.2025.808	d3000.2025.808	NOUN
dentistry3000-808	255	19	h#p://den*stry3000.pi#.edu	h#p://den*stry3000.pi#.edu	PROPN
dentistry3000-808	255	20	38	38	NUM
dentistry3000-808	255	21	.	.	PUNCT
dentistry3000-808	256	1	möller	möller	PROPN
dentistry3000-808	256	2	b	b	PROPN
dentistry3000-808	256	3	,	,	PUNCT
dentistry3000-808	256	4	kollert	kollert	PROPN
dentistry3000-808	256	5	f	f	PROPN
dentistry3000-808	256	6	,	,	PUNCT
dentistry3000-808	256	7	sculean	sculean	PROPN
dentistry3000-808	256	8	a	a	X
dentistry3000-808	256	9	,	,	PUNCT
dentistry3000-808	256	10	villiger	villiger	NOUN
dentistry3000-808	256	11	pm	pm	NOUN
dentistry3000-808	256	12	.	.	PUNCT
dentistry3000-808	257	1	infectious	infectious	ADJ
dentistry3000-808	257	2	triggers	trigger	NOUN
dentistry3000-808	257	3	in	in	ADP
dentistry3000-808	257	4	periodontitis	periodontitis	NOUN
dentistry3000-808	257	5	and	and	CCONJ
dentistry3000-808	257	6	the	the	DET
dentistry3000-808	257	7	gut	gut	NOUN
dentistry3000-808	257	8	in	in	ADP
dentistry3000-808	257	9	rheumatoid	rheumatoid	NOUN
dentistry3000-808	257	10	arthritis	arthritis	NOUN
dentistry3000-808	257	11	(	(	PUNCT
dentistry3000-808	257	12	ra	ra	NOUN
dentistry3000-808	257	13	):	):	PUNCT
dentistry3000-808	257	14	a	a	DET
dentistry3000-808	257	15	complex	complex	ADJ
dentistry3000-808	257	16	story	story	NOUN
dentistry3000-808	257	17	about	about	ADP
dentistry3000-808	257	18	association	association	NOUN
dentistry3000-808	257	19	and	and	CCONJ
dentistry3000-808	257	20	causality	causality	NOUN
dentistry3000-808	257	21	.	.	PUNCT
dentistry3000-808	258	1	frontiers	frontier	NOUN
dentistry3000-808	258	2	in	in	ADP
dentistry3000-808	258	3	immunology	immunology	NOUN
dentistry3000-808	258	4	.	.	PUNCT
dentistry3000-808	259	1	2020	2020	NUM
dentistry3000-808	259	2	jun	jun	PROPN
dentistry3000-808	259	3	3;11:1108	3;11:1108	NUM
dentistry3000-808	259	4	.	.	PUNCT
dentistry3000-808	259	5	39	39	NUM
dentistry3000-808	259	6	.	.	PUNCT
dentistry3000-808	260	1	zekeridou	zekeridou	PROPN
dentistry3000-808	260	2	a	a	X
dentistry3000-808	260	3	,	,	PUNCT
dentistry3000-808	260	4	gilbert	gilbert	PROPN
dentistry3000-808	260	5	b	b	PROPN
dentistry3000-808	260	6	,	,	PUNCT
dentistry3000-808	260	7	finckh	finckh	PROPN
dentistry3000-808	260	8	a	a	DET
dentistry3000-808	260	9	,	,	PUNCT
dentistry3000-808	260	10	giannopoulou	giannopoulou	PROPN
dentistry3000-808	260	11	c.	c.	PROPN
dentistry3000-808	260	12	periodontitis	periodontitis	PROPN
dentistry3000-808	260	13	in	in	ADP
dentistry3000-808	260	14	first	first	ADJ
dentistry3000-808	260	15	degreerelatives	degreerelative	NOUN
dentistry3000-808	260	16	of	of	ADP
dentistry3000-808	260	17	individuals	individual	NOUN
dentistry3000-808	260	18	with	with	ADP
dentistry3000-808	260	19	rheumatoid	rheumatoid	NOUN
dentistry3000-808	260	20	arthritis	arthritis	NOUN
dentistry3000-808	260	21	:	:	PUNCT
dentistry3000-808	260	22	a	a	DET
dentistry3000-808	260	23	short	short	ADJ
dentistry3000-808	260	24	narrative	narrative	NOUN
dentistry3000-808	260	25	review	review	NOUN
dentistry3000-808	260	26	.	.	PUNCT
dentistry3000-808	261	1	frontiers	frontier	NOUN
dentistry3000-808	261	2	in	in	ADP
dentistry3000-808	261	3	oral	oral	ADJ
dentistry3000-808	261	4	health	health	NOUN
dentistry3000-808	261	5	.	.	PUNCT
dentistry3000-808	262	1	2022	2022	NUM
dentistry3000-808	262	2	may	may	AUX
dentistry3000-808	262	3	6;3:895753	6;3:895753	NUM
dentistry3000-808	262	4	.	.	PUNCT
dentistry3000-808	263	1	40	40	NUM
dentistry3000-808	263	2	.	.	PUNCT
dentistry3000-808	264	1	ermencheva	ermencheva	PROPN
dentistry3000-808	264	2	p	p	NOUN
dentistry3000-808	264	3	,	,	PUNCT
dentistry3000-808	264	4	kotov	kotov	ADJ
dentistry3000-808	264	5	g	g	NOUN
dentistry3000-808	264	6	,	,	PUNCT
dentistry3000-808	264	7	shumnalieva	shumnalieva	NOUN
dentistry3000-808	264	8	r	r	NOUN
dentistry3000-808	264	9	,	,	PUNCT
dentistry3000-808	264	10	velikova	velikova	PROPN
dentistry3000-808	264	11	t	t	PROPN
dentistry3000-808	264	12	,	,	PUNCT
dentistry3000-808	264	13	monov	monov	PROPN
dentistry3000-808	264	14	s.	s.	PROPN
dentistry3000-808	264	15	exploring	explore	VERB
dentistry3000-808	264	16	the	the	DET
dentistry3000-808	264	17	role	role	NOUN
dentistry3000-808	264	18	of	of	ADP
dentistry3000-808	264	19	the	the	DET
dentistry3000-808	264	20	microbiome	microbiome	NOUN
dentistry3000-808	264	21	in	in	ADP
dentistry3000-808	264	22	rheumatoid	rheumatoid	NOUN
dentistry3000-808	264	23	arthritis	arthritis	NOUN
dentistry3000-808	264	24	—	—	PUNCT
dentistry3000-808	264	25	a	a	DET
dentistry3000-808	264	26	critical	critical	ADJ
dentistry3000-808	264	27	review	review	NOUN
dentistry3000-808	264	28	.	.	PUNCT
dentistry3000-808	265	1	microorganisms	microorganism	NOUN
dentistry3000-808	265	2	.	.	PUNCT
dentistry3000-808	266	1	2024	2024	NUM
dentistry3000-808	266	2	jul	jul	PROPN
dentistry3000-808	266	3	9;12(7):1387	9;12(7):1387	NOUN
dentistry3000-808	266	4	.	.	PROPN
dentistry3000-808	267	1	41	41	NUM
dentistry3000-808	267	2	.	.	PUNCT
dentistry3000-808	268	1	chow	chow	PROPN
dentistry3000-808	268	2	yc	yc	PROPN
dentistry3000-808	268	3	,	,	PUNCT
dentistry3000-808	268	4	yam	yam	NOUN
dentistry3000-808	268	5	hc	hc	NOUN
dentistry3000-808	268	6	,	,	PUNCT
dentistry3000-808	268	7	gunasekaran	gunasekaran	NOUN
dentistry3000-808	268	8	b	b	PROPN
dentistry3000-808	268	9	,	,	PUNCT
dentistry3000-808	268	10	lai	lai	PROPN
dentistry3000-808	268	11	wy	wy	PROPN
dentistry3000-808	268	12	,	,	PUNCT
dentistry3000-808	268	13	wo	will	AUX
dentistry3000-808	268	14	wy	wy	PROPN
dentistry3000-808	268	15	,	,	PUNCT
dentistry3000-808	268	16	agarwal	agarwal	PROPN
dentistry3000-808	268	17	t	t	PROPN
dentistry3000-808	268	18	,	,	PUNCT
dentistry3000-808	268	19	ong	ong	PROPN
dentistry3000-808	268	20	yy	yy	PROPN
dentistry3000-808	268	21	,	,	PUNCT
dentistry3000-808	268	22	cheong	cheong	PROPN
dentistry3000-808	268	23	sl	sl	PROPN
dentistry3000-808	268	24	,	,	PUNCT
dentistry3000-808	268	25	tan	tan	PROPN
dentistry3000-808	268	26	sa	sa	PROPN
dentistry3000-808	268	27	.	.	PUNCT
dentistry3000-808	268	28	implications	implication	NOUN
dentistry3000-808	268	29	of	of	ADP
dentistry3000-808	268	30	porphyromonas	porphyromona	NOUN
dentistry3000-808	268	31	gingivalis	gingivalis	VERB
dentistry3000-808	268	32	peptidyl	peptidyl	NOUN
dentistry3000-808	268	33	arginine	arginine	NOUN
dentistry3000-808	268	34	deiminase	deiminase	VERB
dentistry3000-808	268	35	and	and	CCONJ
dentistry3000-808	268	36	gingipain	gingipain	VERB
dentistry3000-808	268	37	r	r	NOUN
dentistry3000-808	268	38	in	in	ADP
dentistry3000-808	268	39	human	human	ADJ
dentistry3000-808	268	40	health	health	NOUN
dentistry3000-808	268	41	and	and	CCONJ
dentistry3000-808	268	42	diseases	disease	NOUN
dentistry3000-808	268	43	.	.	PUNCT
dentistry3000-808	269	1	frontiers	frontier	NOUN
dentistry3000-808	269	2	in	in	ADP
dentistry3000-808	269	3	cellular	cellular	ADJ
dentistry3000-808	269	4	and	and	CCONJ
dentistry3000-808	269	5	infection	infection	NOUN
dentistry3000-808	269	6	microbiology	microbiology	NOUN
dentistry3000-808	269	7	.	.	PUNCT
dentistry3000-808	270	1	2022	2022	NUM
dentistry3000-808	270	2	sep	sep	NOUN
dentistry3000-808	270	3	29;12:987683	29;12:987683	NUM
dentistry3000-808	270	4	.	.	PUNCT
dentistry3000-808	271	1	42	42	NUM
dentistry3000-808	271	2	.	.	PUNCT
dentistry3000-808	272	1	kwon	kwon	PROPN
dentistry3000-808	272	2	ej	ej	PROPN
dentistry3000-808	272	3	,	,	PUNCT
dentistry3000-808	272	4	ju	ju	PROPN
dentistry3000-808	272	5	jh	jh	PROPN
dentistry3000-808	272	6	.	.	PUNCT
dentistry3000-808	273	1	impact	impact	NOUN
dentistry3000-808	273	2	of	of	ADP
dentistry3000-808	273	3	posttranslational	posttranslational	ADJ
dentistry3000-808	273	4	modification	modification	NOUN
dentistry3000-808	273	5	in	in	ADP
dentistry3000-808	273	6	pathogenesis	pathogenesis	NOUN
dentistry3000-808	273	7	of	of	ADP
dentistry3000-808	273	8	rheumatoid	rheumatoid	NOUN
dentistry3000-808	273	9	arthritis	arthritis	NOUN
dentistry3000-808	273	10	:	:	PUNCT
dentistry3000-808	273	11	focusing	focus	VERB
dentistry3000-808	273	12	on	on	ADP
dentistry3000-808	273	13	citrullination	citrullination	NOUN
dentistry3000-808	273	14	,	,	PUNCT
dentistry3000-808	273	15	carbamylation	carbamylation	NOUN
dentistry3000-808	273	16	,	,	PUNCT
dentistry3000-808	273	17	and	and	CCONJ
dentistry3000-808	273	18	acetylation	acetylation	NOUN
dentistry3000-808	273	19	.	.	PUNCT
dentistry3000-808	274	1	international	international	ADJ
dentistry3000-808	274	2	journal	journal	NOUN
dentistry3000-808	274	3	of	of	ADP
dentistry3000-808	274	4	molecular	molecular	ADJ
dentistry3000-808	274	5	sciences	science	NOUN
dentistry3000-808	274	6	.	.	PUNCT
dentistry3000-808	275	1	2021	2021	NUM
dentistry3000-808	275	2	sep	sep	NOUN
dentistry3000-808	275	3	30;22(19):10576	30;22(19):10576	NUM
dentistry3000-808	275	4	.	.	PUNCT
dentistry3000-808	275	5	43	43	NUM
dentistry3000-808	275	6	.	.	PUNCT
dentistry3000-808	276	1	pérez	pérez	NOUN
dentistry3000-808	276	2	-	-	PUNCT
dentistry3000-808	276	3	pérez	pérez	NOUN
dentistry3000-808	276	4	me	i	PRON
dentistry3000-808	276	5	,	,	PUNCT
dentistry3000-808	276	6	nietotorres	nietotorre	NOUN
dentistry3000-808	276	7	e	e	NOUN
dentistry3000-808	276	8	,	,	PUNCT
dentistry3000-808	276	9	bollain	bollain	NOUN
dentistry3000-808	276	10	-	-	PUNCT
dentistry3000-808	276	11	y	y	NOUN
dentistry3000-808	276	12	-	-	PUNCT
dentistry3000-808	276	13	goytia	goytia	PROPN
dentistry3000-808	276	14	jj	jj	PROPN
dentistry3000-808	276	15	,	,	PUNCT
dentistry3000-808	276	16	delgadillo	delgadillo	PROPN
dentistry3000-808	276	17	-	-	PUNCT
dentistry3000-808	276	18	ruíz	ruíz	PROPN
dentistry3000-808	276	19	l.	l.	NOUN
dentistry3000-808	276	20	protein	protein	NOUN
dentistry3000-808	276	21	citrullination	citrullination	NOUN
dentistry3000-808	276	22	by	by	ADP
dentistry3000-808	276	23	peptidyl	peptidyl	NOUN
dentistry3000-808	276	24	arginine	arginine	NOUN
dentistry3000-808	276	25	deiminase	deiminase	VERB
dentistry3000-808	276	26	/	/	SYM
dentistry3000-808	276	27	arginine	arginine	NOUN
dentistry3000-808	276	28	deiminase	deiminase	NOUN
dentistry3000-808	276	29	homologs	homolog	NOUN
dentistry3000-808	276	30	in	in	ADP
dentistry3000-808	276	31	members	member	NOUN
dentistry3000-808	276	32	of	of	ADP
dentistry3000-808	276	33	the	the	DET
dentistry3000-808	276	34	human	human	ADJ
dentistry3000-808	276	35	microbiota	microbiota	NOUN
dentistry3000-808	276	36	and	and	CCONJ
dentistry3000-808	276	37	its	its	PRON
dentistry3000-808	276	38	recognition	recognition	NOUN
dentistry3000-808	276	39	by	by	ADP
dentistry3000-808	276	40	anticitrullinated	anticitrullinate	VERB
dentistry3000-808	276	41	protein	protein	NOUN
dentistry3000-808	276	42	antibodies	antibodie	VERB
dentistry3000-808	276	43	.	.	PUNCT
dentistry3000-808	277	1	international	international	ADJ
dentistry3000-808	277	2	journal	journal	NOUN
dentistry3000-808	277	3	of	of	ADP
dentistry3000-808	277	4	molecular	molecular	ADJ
dentistry3000-808	277	5	sciences	science	NOUN
dentistry3000-808	277	6	.	.	PUNCT
dentistry3000-808	278	1	2024	2024	NUM
dentistry3000-808	278	2	may	may	PROPN
dentistry3000-808	278	3	10;25(10):5192	10;25(10):5192	NUM
dentistry3000-808	278	4	.	.	PUNCT