Psychological impact of COVID-19 Vol 10 No 1 (2022) DOI 10.5195/d3000.2022.185 http://dentistry3000.pitt.edu Social isolation in COVID-19: Impact on mental health of young adults Aditi Verma1, Abhishek Mehta1 1 Department of Public Health Dentistry, Faculty of Dentistry, Jamia Millia Islamia, New-Delhi, India Abstract Background: The coronavirus disease (COVID-19) is profoundly affecting life around the globe. Social Isolation, contact restrictions and economic shutdown impose a complete change to the psychosocial environment threatening the mental health of young adults significantly. Objectives: The present study aims to assess the impact of Social Isolation on the mental health of young adults during the pandemic. Methods: A web based research was conducted on a sample of 438 college students of age 18-24 years. The participants were asked for responding to a standardized online questionnaire that included questions related to their anxiety levels and the 7-item Generalized Anxiety Disorder Scale (GAD-7). Results: The results revealed 78.4% of the study populations were suffering with mild (35.2%), moderate (23.7%), and severe anxiety (19.4%) respectively. Univariate and Logistic Regression Analysis revealed gender and course/year of study had a significant effect on the level of anxiety (p<0.05). Also, students living alone and having a relative or an acquaintance infected with COVID-19 were likely to be more anxious (p<0.05). Spearman correlation analysis depicted Social Isolation as the main Covid-19 related stressor which was positively correlated and highly significant (p=0.0001) to the level of anxiety of young adults. Conclusions: The present study revealed approximately 43% of young adults is suffering from moderate to severe anxiety levels which require urgent attention. Keywords: Social isolation, Mental Health, Young adults, India, COVID-19 pandemic. Citation: Verma A and Mehta A. (2022) Social isolation in COVID-19: impact on mental health of young adults. Dentistry 3000. 1:a001 doi:10.5195/d3000.2022.185 Received: May 13, 2021 Accepted: May 27, 2021 Published: April 30, 2022 Copyright: ©2022 Verma A and Mehta A. This is an open access article licensed under a Creative Commons Attribution Work 4.0 United States License. Email: averma1@jmi.ac.in Introduction The world is going through a major health and socio-economic crisis due to the emergence of novel Corona Virus Disease (COVID-19). The best option available for breaking the chain of transmission of this viral infection is with Social Isolation. As of 23rd March, 2020, all schools, colleges and educational institutions have been suspended under nationwide lockdown by the Government of India. The continuous rise in cases coupled with social isolation measures such as the delay in the opening of schools, colleges/ universities or educational institutions across the country, closure of shopping malls and restrictions on social gatherings it is expected that the mental health of young adults is influenced [1]. These measures resulted in the major disruptions in the daily routines of socializing in schools, colleges and educational institutions which were important stress coping mechanisms for young adults [2]. Research suggests that this social isolation could lead to various psychological- related disorders if they are left unattended [3, 4]. Several studies have already reported the negative psychological impact of pandemic on different age-groups [1, 3-5]. According to a review, young adults who feel lonely might be as much as three times more likely to develop depression in the future and that the impact of this loneliness on mental health could last for at least 9 years [3]. http://dentistry3000.pitt.edu/ Psychological impact of COVID-19 Vol 10 No 1 (2022) DOI 10.5195/d3000.2022.185 http://dentistry3000.pitt.edu However, we found only a single Indian published literature focusing on understanding the mental state of youth during the current crisis [6]. Hence, the present study was conducted with an aim to assess the psychological impact of social isolation during COVID-19 pandemic on the mental health of young adults with the objectives: a. Evaluate the level of anxiety among young adults during this pandemic period; b. Evaluate the relationship between the COVID related stressors and anxiety. Materials and Methods A cross-sectional web-based study was conducted on a sample of 438 college students of age group 18-24 years (young adults) irrespective of courses enrolled from Jamia Millia Islamia University, New-Delhi, India. The snow-ball sampling method was utilized to achieve desired study sample. The minimum sample size of this study ‘n’ was estimated based on earlier study [6]. Ethical Issues and consent The study proposal was reviewed and approved Faculty of Dentistry, Jamia Millia Islamia Institutional Review Board (No. FOD/IRRC/40/2020/F/2072020) prior to the commencement of the study. The research was conducted in concordance with the provisions of the Declaration of Helsinki regarding research on human participants. Informed consent was obtained from the study participants prior to the commencement of study after being informed about the study purpose. Eligibility Criteria Students enrolled in various courses of Jamia Millia Islamia University and of age less than 25 years were eligible for participation in this study. Students on medications for any psychiatric disorder or anxiety issues or were unwilling to provide informed consent were excluded from the study. Data Collection A structured online questionnaire was prepared on Google forms referenced from an earlier study [1] with a consent form appended to it. The link of the questionnaire was sent through emails and WhatsApp to the university students 4 months post- lockdown. The data collection was initiated on 1st August 2020 at 10 AM IST and closed on 5th August 2020 at 10AM IST. The students who are willing to participate voluntarily in this study were invited to fill the questionnaire after taking their due informed consent. The participants were encouraged to roll out the survey to as many students as possible. Thus, the link was forwarded to students apart from the first point of contact and so on. On receiving and clicking the link the participants got auto directed to the information about the study and informed consent. Participants with access to the internet could participate in the study. After inquiring about the general demographic information such as age, gender, place of residence, the participants were inquired about the COVID-19 related stress factors such as its economic influence, academic delays and social isolation along with the availability of social support. A standardized Generalized Anxiety Disorder Scale (GAD-7) [2] was used to measure the anxiety levels of the respondents. The GAD-7 includes seven items based on seven core symptoms and inquires the frequency with which respondents suffered from these symptoms within the last two weeks. Respondents report their symptoms using a 4-item Likert rating scale ranging from 0 (not at all) to 3 (almost every day), such that the total score ranges from 0 to 21. The GAD-7 is a well-validated screening instrument, and it has demonstrated excellent internal consistency (Cronbach's ɑ = 0.911) [3]. The level of anxiety and its probable causal factors (COVID-19 stressors) among university students during the pandemic were investigated. Statistical Analysis The data obtained were analyzed with a Statistical Package for the Social Sciences v22 (SPSS Inc; http://www.spss.com). Descriptive statistics were performed for illustrating the baseline characteristics of the respondents while univariate analysis was employed to check for the association between the respondent’s characteristics and their level of anxiety. The association between http://dentistry3000.pitt.edu/ Psychological impact of COVID-19 Vol 10 No 1 (2022) DOI 10.5195/d3000.2022.185 http://dentistry3000.pitt.edu COVID-19 related stressors and anxiety levels were evaluated by Spearman’s correlation coefficient. Results A total of 438 study participants were included in the present study comprising of 131 (30%) males and 307 (70%) females. Mean age of the study participants was 22.15 ±1.93 years. The majority of the participants were living in urban areas (70%); 82.9% (n = 363) were staying with their parents and have a steady source of income while 17% (n = 75) of the parents of students did not have a steady income. More than ¾ (78.8%) of the participants reported that none of their relatives or acquaintances are or were infected with COVID-19 while 21% (n = 93) of the participants had relatives or acquaintances who were infected with COVID-19 [Table 1]. Level of anxiety among students The mental health of the participants was affected during the pandemic to varying extent. The total of 438 study participants, only 21.6% reported no symptoms of anxiety whereas the proportions of students with mild, moderate, and severe anxiety were 35.2%, 23.7%, and 19.4%, respectively [Table 2]. Factors influencing students’ anxiety Univariate analysis revealed gender and course/year of study had a significant effect on the level of anxiety among the study participants whereas place of residence and families with steady source of income Table 1. Comparison of different independent variables with severity of anxiety levels of study participants. VARIABLES TOTAL NO/ MINIMAL MILD MODERATE SEVERE P GENDER Male 131 38 42 31 20 0.038a Female 307 57 112 73 65 PLACE OF RESIDENCE Urban 345 73 120 79 73 0.483b Rural 34 7 15 9 3 Urban-Rural 59 15 19 16 9 COURSE/YEAR OF STUDY BDS 186 41 61 48 36 0.003a Others than BDS 252 54 93 56 49 STEADY FAMILY INCOME Yes 363 81 126 88 68 0.535a No 75 14 28 16 17 SOCIAL SUPPORT/ LIVE WITH PARENTS Yes 363 82 130 95 56 0.009a No 75 13 24 9 29 RELATIVE OR ACQUINTAINCE GOT COVID-19 Yes 93 14 32 24 23 0.042a No 345 81 122 80 62 aMan-Whitney U – Test, bKruskal Wallis Test http://dentistry3000.pitt.edu/ Psychological impact of COVID-19 Vol 10 No 1 (2022) DOI 10.5195/d3000.2022.185 http://dentistry3000.pitt.edu had no significant effect on the anxiety levels. Moreover, students living alone and having a relative or an acquaintance infected with COVID- 19 were more likely to be more anxious [Table 1]. Table 2. Frequency distribution of study participants with different anxiety levels (n=438). ANXIETY LEVEL NUMBER RATIO Minimal anxiety 95 21.6 Mild anxiety 154 35.2 Moderate anxiety 104 23.7 Severe anxiety 85 19.4 Significant factors from the univariate analysis were included in the ordinal logistic regression analysis. In the model test, p<0.05, indicating that the OR value of at least one variable was statistically significant. Therefore, χ2 = 27.197, p>0.05, obtained in the test of parallel lines indicated a good model fit with the observed values. The results showed that having a social support, i.e. staying with their parents was one of the significant protective factors against students’ anxiety (OR = 0.246, 95%CI = 0.387 - 1.352) while gender, course/year of study were other significant risk factors for anxiety [Table 3]. Correlation between the COVID-19- related stressors and levels of students’ anxiety Worrying about the economic influences of the epidemic and academic delays were positively related to the levels of anxiety in college students but was not statistically significant. Moreover, the influence of social isolation/lockdown in terms of affecting their daily life, feeling of limitation of identity and anxiousness were positively correlated and were highly significant with the levels of anxiety [Table 4]. Table 3. Frequency distribution of study participants with different anxiety levels (n=438). FACTORS NUMBER SE OR P 95%CI GENDER Female 307 0.207 0.459 0.027 (0.053, 0.864) Malea 131 - - - - COURSES/ YEAR OF STUDY 1st Year BDS 38 0.407 1.218 0.003 (0.421, 2.015) 2nd Year BDS 35 0.405 1.073 0.008 (0.280, 1.867) 3rd Year BDS 31 0.428 1.392 0.001 (0.554, 2.231) Final Year BDS 46 0.382 0.915 0.017 (0.166, 1.664) Internship 36 0.333 0.757 0.023 (0.105, 1.410) Other than BDSa 252 - - - - SOCIAL SUPPORT/LIVE WITH PARENTS Yes 363 0.870 0.246 0.000 (0.387, 1.352) Noa 75 - - - - RELATIVE OR ACQUINTAINCE GOT COVID-19 No 345 0.222 -0.217 0.327 (-0.652, 0.217) Yesa 93 - - - - *Ordinal Regression Analysis, aMan-Whitney U - Test, bKruskal Wallis Test http://dentistry3000.pitt.edu/ Psychological impact of COVID-19 Vol 10 No 1 (2022) DOI 10.5195/d3000.2022.185 http://dentistry3000.pitt.edu Table 4: Correlation analysis between COVID related stressors and students anxiety. COVID STRESSORS ANXIETY LEVELS P Worried about economic influence 0.064 0.114 Worried about academic delays 0.084 0.078 Social isolation/ lockdown influences on my daily life 0.242 0.000 Social isolation/ lockdown is my limiting identity 0.273 0.000 Feeling Anxious because of social isolation/lockdown 0.174 0.000 *Spearman’s Co-relation Discussion The anxiety and other psychological concerns of society are globally affecting every individual to variable extents. Recent evidence suggests that individuals who are kept in isolation experience significant distress in the form of anxiety, anger, confusion and post-traumatic stress symptoms [7]. The aim of this study was to evaluate the psychological impact of the current pandemic on the college students and explore underlying factors influencing their anxiety. The present study revealed that the majority of the college students (nearly 80%) were tormented with higher anxiety levels because of the COVID-19 outbreak. The anxiety levels reported in the present study were higher than in the previous studies done by Cao W et al (24.9%) and Gaikwad S (48%). The probable reason for reporting such higher anxiety levels may be because of their stronger association with the duration of the social isolation [3]. In India, the educational institutions and colleges have been closed since mid- march and we conducted this research after 4 months of social isolation. It is known anxiety disorders are more likely to occur and worsen in the absence of interpersonal communication [8]. Another factor may be students in India are still uncertain about the impact of pandemic on their academic year and future employment opportunities. The results also suggested that students' anxiety regarding the epidemic was associated with gender, course/year of study, whether living with parents and whether a relative or an acquaintance was infected with COVID-19. This difference in anxiety levels on the basis of gender predilection is in line with the previous studies [3, 9] but is in contrast with the study done in China [1]. The difference indicates that male and female students experienced the difference in levels of stresses and negative emotions as a result of the pandemic. However, no significant difference was reported in source of parental income or place of residence, which was different from previous findings [1]. The year/course of study were also reported to be another variable associated with student’s anxiety. The present study reported significant levels of anxiety among the dental students in comparison to other courses. The probable reason could be the possibility of acquiring the disease while treating the patients which is a part of their under- graduate curriculum is higher in comparison to the other non- specialized courses. Previous studies [1, 10] have also indicated that the risk factors associated with emotional and anxiety disorders in adults include not living with parents which are consistent with the results of this study. Among the COVID related stressors the social isolation/ lockdown reported to be positively associated and had a significant impact among the anxiety levels of students. This is in line with the previous study [3]. Although economic influence and academic delays were also reported to be positively associated with anxiety but were not statistically significant. This is in contrast to the previous study done in China [1]. This suggests that the current social isolation measures enforced because of COVID-19 could lead to an increase in mental health problems among college students and is particularly becoming problematic for young adults. Some strengths and limitations of this study can be noted. The use of the robust methodology and the standardized anxiety scale for detecting small correlations is the major strength of this study. Whilst the limitations include the cross- http://dentistry3000.pitt.edu/ Psychological impact of COVID-19 Vol 10 No 1 (2022) DOI 10.5195/d3000.2022.185 http://dentistry3000.pitt.edu sectional nature of the study, self- report nature of the questionnaire may exhibit social desirability bias and may limit the generalizability of our results to a wider population. Conclusion Of the total study participants, 19.4% experienced severe anxiety and 23.7% experienced moderate anxiety levels which needs psychological interventions. Thus, there are numerous mental health threats associated with the current pandemic and subsequent restrictions. Finding ways to give young adults a sense of belonging within the family and to feel that they are part of a wider community should be a priority. Helping them to identify valued alternative activities and build structures and purpose into periods of involuntary social isolation may help to provide a wider range of rewards. Addressing negative thoughts about social encounters (e.g. self-blame, self-devaluation) may also be effective. Digital Technology that provides evidence- based interventions to help young adults to reappraise their thoughts and change their behavior within the confines of the home setting should be [3]. Hence, it is pertinent to understand and investigate the psychological states of our young minds during these hard times and provide them with appropriate help and support from the family, institutions/colleges and society at large. Acknowledgement None. Conflicts of Interest The authors have no conflict of interest to disclose. Funding This research did not receive any specific grants from funding agencies in the public, commercial or not-for- profit sectors. References 1. Cao W, Fang Z, Hou G et al. 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Child Adolesc Psychiatry Ment Health 2020; 14:20. 6. Gaikwad S. Psychological Impact of COVID-19 on Adolescents. Purakala. 2020 May; 31(37):639-643. 7. Brooks SK, Webster RK, Smith LE et al. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. The Lancet. 2020 February; 395 (10227):912-920. 8. Xiao C. A novel approach of consultation on 2019 novel coronavirus (COVID-19)-Related psychological and mental problems: structured letter therapy. Psychiatry Investig. 2020; 17 (2), 175–176. 9. Moreno E, Muñoz-Navarro R, Medrano LA et al. Factorial in variance of a computerized version of the GAD-7 across various demographic groups and over time in primary care patients. J. Affect Disord. 2019; 252, 114–121. 10. Woodgate RL, Tailor K, Tennent P et al. The experience of the self in Canadian youth living with anxiety: a qualitative study. PLoS ONE. 2020; 15 (1),e0228193. http://dentistry3000.pitt.edu/