Dermatology: Practical and Conceptual Image Letter | Dermatol Pract Concept 2021;11(2):e2021015 1 Dermatology Practical & Conceptual Is It Possible to Improve Scabies Diagnosis Performance? Vincenzo Greco1, Massimiliano Scalvenzi1, Gabriella Fabbrocini1, Matteo Megna1 1 Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy Key words: scabies, mite, feces, eggs, jetliner, jet trail, polarized light, dermoscopy Citation: Greco V, Scalvenzi M, Fabbrocini G, Megna M. Is it possible to improve scabies diagnosis performance? Dermatol Pract Concept. 2021;11(2):e2021015. DOI: https://doi.org/10.5826/dpc.1102a15 Accepted: August 31, 2020; Published: April 12, 2021 Copyright: ©2021 Greco et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License BY- NC-4.0, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: None. Competing interests: The authors have no conflicts of interest to disclose. Authorship: All authors have contributed significantly to this publication. Corresponding author: Vincenzo Greco, MD, Department of Dermatology, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. Email: vingreco@live.com Case Presentation We present the same case of scabies (Figure 1A) photographed with a new polarized light dermoscope (Figure 1B) and with an older immersion contact dermoscope (Figure 1C). Teaching Point Dermoscopy allows a high sensitivity and specificity for scabies diagnosis [1]. Although modern dermoscopes with polarized light can better analyze pigmented lesions Figure 1. (A) Scabies: clinical aspects. (B) Polarized light dermoscopy. (C) Immersion contact dermoscopy. 2 Image Letter | Dermatol Pract Concept 2021;11(2):e2021015 without necessitating a liquid interface or direct skin contact with the instrument, they do not perform as well when interpreting superficial epidermal lesions of scabies. Note that, with new polarized light dermoscopes, the “jet trail” (the burrow) is easily visible, but a clear differen- tiation of artefacts induced by scratching or small dirt particles is not easy to obtain [2]. Paradoxically, scabies was more easily detected in the past with older dermo- scopes because immersion contact dermoscopy reduces the reflection capacity of keratinocytes of the burrow so that the “jetliner,” feces, and eggs that are usually covered by the shiny keratinocytes of the jet trail, are better detected. In conclusion, we suggest using older dermoscopes or the immersion technique for mite search. References 1. Marghoob AA, Swindle LD, Moricz CZ, et al. Instruments and new technologies for the in vivo diagnosis of melanoma. J Am Acad Dermatol. 2003;49(5):777–799. DOI: 10.1016/s0190- 9622(03)02470-8. PMID: 14576657 2. Micali G, Lacarrubba F, Verzì AE, Chosidow O, Schwartz RA. Scabies: advances in noninvasive diagnosis. PLoS Negl Trop Dis. 2016;10(6):e0004691. DOI: 10.1371/journal.pntd.0004691. PMID: 27311065.