id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
dpc-1184	Weyers, Wolfgang	“Mitogenicity”—the latest and most hilarious episode in the slapstick comedy of melanoma management. 	2012	8	.pdf	application/pdf	6709	355	60	And those who contend that a few melanoma cells confined to the epidermis have an independent effect on prognosis are the same who aver that a wholly intraepidermal prolifera- tion of melanoma cells carries no risk at all, who even claim that there is “no biologic evidence that in situ melanoma is a malignant disease.” [4] Fif- teen years later, in order to satisfy the concept of multistep carcinogenesis, he returned to the position that melanomas resulted from transformation of melanocytic nevi in what he called “six evident lesional steps of tumor progression,” namely, “1) the common acquired melanocytic nevus; 2) a melanocytic nevus with lentiginous melanocytic hyperplasia, i.e., aberrant differentiation; 3) a melanocytic nevus with aberrant differentiation and nuclear atypia, i.e., melanocytic dysplasia; 4) the radial growth phase of primary melanoma; 5) the vertical growth phase of primary melanoma; and 6) metastatic melanoma.”	cache/dpc-1184.pdf	txt/dpc-1184.txt