id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
dpc-232	Millán-Cayetano, José-Francisco; Yelamos, Oriol; Rossi, Anthony M; Marchetti, Michael A.; Jain, Manu	Reflectance confocal microscopy features of facial angiofibromas	2017	4	.pdf	application/pdf	1518	87	45	Conversely, RCM images of basal cell carcinoma (panels E and F; ~0.75 mm x 0.75 mm; taken from a separate case) show tumor nodules with clefting and palisading (red ar- rowheads, panel E), horizontal canalicular vessels (red arrows, panel E), and an inflammatory stroma with numerous small bright cells (red rectangle, panel F) and plump bright cells (red ellipse, panel F). Reflectance confocal microscopy Angiofibroma Basal cell carcinoma Reflectance confocal microscopy Histopathology Reflectance confocal microscopy Histopathology Epidermis • Normal epidermis with regular honeycomb pattern • Normal epidermis • Epidermal streaming • Variable epidermal disarray • Keratinocytes focally elongated along the same axis • Variable epidermal pleomorphism DEJ and superficial dermis Aggregates • Nodules with increased cellular density and occasional clefting (BCClike structures) • Epidermal invagination in the papillary dermis or superficial portion of external root sheath of hair follicle • Tumor islands • Cordlike structures with palisading • Clefting • Dark silhouettes • Tumor nodules comprised of atypical basaloid cells with peripheral palisading • Cords of atypical basaloid cells • Peritumoral mucin/clefting • Aggregates of tumor cells Vascularization • Small round to linear and canalicular vessels • Increased vascularization with variablysized dilated blood vessels • Horizontal “enface” canalicular vessels with leukocyte rolling/trafficking • Prominent, dilated and enlarged blood vessels Collagen • Thickened collagen bundles surrounding hair follicles and BCClike structures • Thickened collagen bundles arranged around hair follicles • Gossamer like stroma wrapping around tumor islands •	cache/dpc-232.pdf	txt/dpc-232.txt