id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
dpc-5329	Paz, Meshi; Lio, Peter	Skin-Immune-Neuro-Gastro-Endocrine (SINGE) System: Lighting the Fire on Atopic Dermatitis Research	2025	8	.pdf	application/pdf	4315	405	49	In AD, skin barrier dysfunction lays the foundation for disease progression. Conclusion The pathophysiology of AD reveals its multifactorial nature and is best understood through the SINGE network, which includes elements such as skin barrier dysfunction, immune dysregulation, neuropeptide involvement, gut microbiota contributions, and the endocrine stress axes.	cache/dpc-5329.pdf	txt/dpc-5329.txt