id	sid	tid	token	lemma	pos
dpc-1303	1	1	dermatology	dermatology	NOUN
dpc-1303	1	2	:	:	PUNCT
dpc-1303	1	3	practical	practical	ADJ
dpc-1303	1	4	and	and	CCONJ
dpc-1303	1	5	conceptual	conceptual	ADJ
dpc-1303	1	6	research	research	NOUN
dpc-1303	1	7	|	|	ADV
dpc-1303	1	8	dermatol	dermatol	ADJ
dpc-1303	1	9	pract	pract	NOUN
dpc-1303	1	10	concept	concept	NOUN
dpc-1303	1	11	2021;11(2):e2021035	2021;11(2):e2021035	NUM
dpc-1303	1	12	1	1	NUM
dpc-1303	1	13	dermatology	dermatology	NOUN
dpc-1303	1	14	practical	practical	ADJ
dpc-1303	1	15	&	&	CCONJ
dpc-1303	1	16	conceptual	conceptual	PROPN
dpc-1303	1	17	decreased	decrease	VERB
dpc-1303	1	18	serum	serum	NOUN
dpc-1303	1	19	levels	level	NOUN
dpc-1303	1	20	of	of	ADP
dpc-1303	1	21	interleukin-4	interleukin-4	NUM
dpc-1303	1	22	and	and	CCONJ
dpc-1303	1	23	interleukin-21	interleukin-21	PROPN
dpc-1303	1	24	in	in	ADP
dpc-1303	1	25	new	new	ADJ
dpc-1303	1	26	pemphigus	pemphigus	NOUN
dpc-1303	1	27	vulgaris	vulgaris	NOUN
dpc-1303	1	28	patients	patient	NOUN
dpc-1303	1	29	,	,	PUNCT
dpc-1303	1	30	but	but	CCONJ
dpc-1303	1	31	not	not	PART
dpc-1303	1	32	chronic	chronic	ADJ
dpc-1303	1	33	patients	patient	NOUN
dpc-1303	1	34	with	with	ADP
dpc-1303	1	35	inactive	inactive	ADJ
dpc-1303	1	36	disease	disease	NOUN
dpc-1303	1	37	compared	compare	VERB
dpc-1303	1	38	to	to	ADP
dpc-1303	1	39	healthy	healthy	ADJ
dpc-1303	1	40	controls	control	NOUN
dpc-1303	1	41	pegah	pegah	PROPN
dpc-1303	1	42	shahbazian1	shahbazian1	PROPN
dpc-1303	1	43	,	,	PUNCT
dpc-1303	1	44	maryam	maryam	PROPN
dpc-1303	1	45	izad2,3	izad2,3	PROPN
dpc-1303	1	46	,	,	PUNCT
dpc-1303	1	47	maryam	maryam	PROPN
dpc-1303	1	48	daneshpazhooh1	daneshpazhooh1	PROPN
dpc-1303	1	49	,	,	PUNCT
dpc-1303	1	50	hossein	hossein	PROPN
dpc-1303	1	51	mortazavi3	mortazavi3	PROPN
dpc-1303	1	52	,	,	PUNCT
dpc-1303	1	53	zahra	zahra	PROPN
dpc-1303	1	54	salehi2	salehi2	PROPN
dpc-1303	1	55	,	,	PUNCT
dpc-1303	1	56	shirin	shirin	PROPN
dpc-1303	1	57	behruzifar1	behruzifar1	PROPN
dpc-1303	1	58	,	,	PUNCT
dpc-1303	1	59	soheil	soheil	PROPN
dpc-1303	1	60	tavakolpour1,4	tavakolpour1,4	PROPN
dpc-1303	1	61	,	,	PUNCT
dpc-1303	1	62	arghavan	arghavan	NOUN
dpc-1303	1	63	azizpour1	azizpour1	NOUN
dpc-1303	1	64	1	1	NUM
dpc-1303	1	65	autoimmune	autoimmune	ADJ
dpc-1303	1	66	bullous	bullous	ADJ
dpc-1303	1	67	diseases	disease	NOUN
dpc-1303	1	68	research	research	NOUN
dpc-1303	1	69	center	center	NOUN
dpc-1303	1	70	,	,	PUNCT
dpc-1303	1	71	department	department	NOUN
dpc-1303	1	72	of	of	ADP
dpc-1303	1	73	dermatology	dermatology	NOUN
dpc-1303	1	74	,	,	PUNCT
dpc-1303	1	75	razi	razi	PROPN
dpc-1303	1	76	hospital	hospital	PROPN
dpc-1303	1	77	,	,	PUNCT
dpc-1303	1	78	tehran	tehran	PROPN
dpc-1303	1	79	university	university	PROPN
dpc-1303	1	80	of	of	ADP
dpc-1303	1	81	medical	medical	ADJ
dpc-1303	1	82	sciences	sciences	PROPN
dpc-1303	1	83	,	,	PUNCT
dpc-1303	1	84	tehran	tehran	PROPN
dpc-1303	1	85	,	,	PUNCT
dpc-1303	1	86	iran	iran	PROPN
dpc-1303	1	87	2	2	NUM
dpc-1303	1	88	department	department	NOUN
dpc-1303	1	89	of	of	ADP
dpc-1303	1	90	immunology	immunology	NOUN
dpc-1303	1	91	,	,	PUNCT
dpc-1303	1	92	school	school	NOUN
dpc-1303	1	93	of	of	ADP
dpc-1303	1	94	medicine	medicine	NOUN
dpc-1303	1	95	,	,	PUNCT
dpc-1303	1	96	tehran	tehran	PROPN
dpc-1303	1	97	university	university	PROPN
dpc-1303	1	98	of	of	ADP
dpc-1303	1	99	medical	medical	ADJ
dpc-1303	1	100	sciences	sciences	PROPN
dpc-1303	1	101	,	,	PUNCT
dpc-1303	1	102	tehran	tehran	PROPN
dpc-1303	1	103	,	,	PUNCT
dpc-1303	1	104	iran	iran	PROPN
dpc-1303	1	105	3	3	NUM
dpc-1303	1	106	ms	ms	PROPN
dpc-1303	1	107	research	research	NOUN
dpc-1303	1	108	center	center	NOUN
dpc-1303	1	109	,	,	PUNCT
dpc-1303	1	110	neuroscience	neuroscience	PROPN
dpc-1303	1	111	institute	institute	PROPN
dpc-1303	1	112	,	,	PUNCT
dpc-1303	1	113	tehran	tehran	PROPN
dpc-1303	1	114	university	university	PROPN
dpc-1303	1	115	of	of	ADP
dpc-1303	1	116	medical	medical	ADJ
dpc-1303	1	117	sciences	sciences	PROPN
dpc-1303	1	118	,	,	PUNCT
dpc-1303	1	119	tehran	tehran	PROPN
dpc-1303	1	120	,	,	PUNCT
dpc-1303	1	121	iran	iran	PROPN
dpc-1303	1	122	4	4	NUM
dpc-1303	1	123	dana	dana	PROPN
dpc-1303	1	124	-	-	PUNCT
dpc-1303	1	125	farber	farber	PROPN
dpc-1303	1	126	cancer	cancer	PROPN
dpc-1303	1	127	institute	institute	PROPN
dpc-1303	1	128	,	,	PUNCT
dpc-1303	1	129	harvard	harvard	PROPN
dpc-1303	1	130	medical	medical	PROPN
dpc-1303	1	131	school	school	PROPN
dpc-1303	1	132	,	,	PUNCT
dpc-1303	1	133	boston	boston	PROPN
dpc-1303	1	134	,	,	PUNCT
dpc-1303	1	135	usa	usa	PROPN
dpc-1303	1	136	key	key	NOUN
dpc-1303	1	137	words	word	NOUN
dpc-1303	1	138	:	:	PUNCT
dpc-1303	1	139	pemphigus	pemphigus	NOUN
dpc-1303	1	140	vulgaris	vulgaris	NOUN
dpc-1303	1	141	,	,	PUNCT
dpc-1303	1	142	elisa	elisa	NOUN
dpc-1303	1	143	,	,	PUNCT
dpc-1303	1	144	cytokine	cytokine	NOUN
dpc-1303	1	145	,	,	PUNCT
dpc-1303	1	146	interleukin-4	interleukin-4	PROPN
dpc-1303	1	147	,	,	PUNCT
dpc-1303	1	148	interleukin-21	interleukin-21	PROPN
dpc-1303	1	149	citation	citation	NOUN
dpc-1303	1	150	:	:	PUNCT
dpc-1303	1	151	shabazian	shabazian	PROPN
dpc-1303	1	152	p	p	NOUN
dpc-1303	1	153	,	,	PUNCT
dpc-1303	1	154	izad	izad	PROPN
dpc-1303	1	155	m	m	PRON
dpc-1303	1	156	,	,	PUNCT
dpc-1303	1	157	daneshpazhooh	daneshpazhooh	PROPN
dpc-1303	1	158	m	m	PRON
dpc-1303	1	159	,	,	PUNCT
dpc-1303	1	160	mortazavi	mortazavi	ADJ
dpc-1303	1	161	h	h	NOUN
dpc-1303	1	162	,	,	PUNCT
dpc-1303	1	163	salehi	salehi	PROPN
dpc-1303	1	164	z	z	PROPN
dpc-1303	1	165	,	,	PUNCT
dpc-1303	1	166	behruzifar	behruzifar	ADV
dpc-1303	1	167	s	s	PRON
dpc-1303	1	168	,	,	PUNCT
dpc-1303	1	169	tavakolpour	tavakolpour	PROPN
dpc-1303	1	170	s	s	NOUN
dpc-1303	1	171	,	,	PUNCT
dpc-1303	1	172	azizpour	azizpour	ADJ
dpc-1303	1	173	a.	a.	NOUN
dpc-1303	1	174	decreased	decrease	VERB
dpc-1303	1	175	serum	serum	NOUN
dpc-1303	1	176	levels	level	NOUN
dpc-1303	1	177	of	of	ADP
dpc-1303	1	178	interleukin-4	interleukin-4	NUM
dpc-1303	1	179	and	and	CCONJ
dpc-1303	1	180	interleukin-21	interleukin-21	PROPN
dpc-1303	1	181	in	in	ADP
dpc-1303	1	182	new	new	ADJ
dpc-1303	1	183	pemphigus	pemphigus	NOUN
dpc-1303	1	184	vulgaris	vulgaris	NOUN
dpc-1303	1	185	patients	patient	NOUN
dpc-1303	1	186	,	,	PUNCT
dpc-1303	1	187	but	but	CCONJ
dpc-1303	1	188	not	not	PART
dpc-1303	1	189	chronic	chronic	ADJ
dpc-1303	1	190	patients	patient	NOUN
dpc-1303	1	191	with	with	ADP
dpc-1303	1	192	inactive	inactive	ADJ
dpc-1303	1	193	disease	disease	NOUN
dpc-1303	1	194	compared	compare	VERB
dpc-1303	1	195	to	to	ADP
dpc-1303	1	196	healthy	healthy	ADJ
dpc-1303	1	197	controls	control	NOUN
dpc-1303	1	198	.	.	PUNCT
dpc-1303	2	1	dermatol	dermatol	NOUN
dpc-1303	2	2	pract	pract	PROPN
dpc-1303	2	3	concept	concept	NOUN
dpc-1303	2	4	.	.	PUNCT
dpc-1303	3	1	2021;11(2):e2021035	2021;11(2):e2021035	X
dpc-1303	3	2	.	.	X
dpc-1303	3	3	doi	doi	NOUN
dpc-1303	3	4	:	:	PUNCT
dpc-1303	3	5	https://doi.org/10.5826/dpc.1102a35	https://doi.org/10.5826/dpc.1102a35	VERB
dpc-1303	3	6	accepted	accept	VERB
dpc-1303	3	7	:	:	PUNCT
dpc-1303	3	8	october	october	PROPN
dpc-1303	3	9	22	22	NUM
dpc-1303	3	10	,	,	PUNCT
dpc-1303	3	11	2020	2020	NUM
dpc-1303	3	12	;	;	PUNCT
dpc-1303	3	13	published	publish	VERB
dpc-1303	3	14	:	:	PUNCT
dpc-1303	3	15	april	april	PROPN
dpc-1303	3	16	12	12	NUM
dpc-1303	3	17	,	,	PUNCT
dpc-1303	3	18	2021	2021	NUM
dpc-1303	3	19	copyright	copyright	NOUN
dpc-1303	3	20	:	:	PUNCT
dpc-1303	4	1	©	©	PROPN
dpc-1303	4	2	2021	2021	NUM
dpc-1303	4	3	shahbazian	shahbazian	NOUN
dpc-1303	4	4	et	et	PROPN
dpc-1303	4	5	al	al	PROPN
dpc-1303	4	6	.	.	PUNCT
dpc-1303	5	1	this	this	PRON
dpc-1303	5	2	is	be	AUX
dpc-1303	5	3	an	an	DET
dpc-1303	5	4	open	open	ADJ
dpc-1303	5	5	-	-	PUNCT
dpc-1303	5	6	access	access	NOUN
dpc-1303	5	7	article	article	NOUN
dpc-1303	5	8	distributed	distribute	VERB
dpc-1303	5	9	under	under	ADP
dpc-1303	5	10	the	the	DET
dpc-1303	5	11	terms	term	NOUN
dpc-1303	5	12	of	of	ADP
dpc-1303	5	13	the	the	DET
dpc-1303	5	14	creative	creative	ADJ
dpc-1303	5	15	commons	common	NOUN
dpc-1303	5	16	attribution	attribution	NOUN
dpc-1303	5	17	license	license	NOUN
dpc-1303	5	18	by	by	ADP
dpc-1303	5	19	-	-	PUNCT
dpc-1303	5	20	nc-4.0	nc-4.0	NOUN
dpc-1303	5	21	,	,	PUNCT
dpc-1303	5	22	which	which	PRON
dpc-1303	5	23	permits	permit	VERB
dpc-1303	5	24	unrestricted	unrestricted	ADJ
dpc-1303	5	25	noncommercial	noncommercial	ADJ
dpc-1303	5	26	use	use	NOUN
dpc-1303	5	27	,	,	PUNCT
dpc-1303	5	28	distribution	distribution	NOUN
dpc-1303	5	29	,	,	PUNCT
dpc-1303	5	30	and	and	CCONJ
dpc-1303	5	31	reproduction	reproduction	NOUN
dpc-1303	5	32	in	in	ADP
dpc-1303	5	33	any	any	DET
dpc-1303	5	34	medium	medium	NOUN
dpc-1303	5	35	,	,	PUNCT
dpc-1303	5	36	provided	provide	VERB
dpc-1303	5	37	the	the	DET
dpc-1303	5	38	original	original	ADJ
dpc-1303	5	39	authors	author	NOUN
dpc-1303	5	40	and	and	CCONJ
dpc-1303	5	41	source	source	NOUN
dpc-1303	5	42	are	be	AUX
dpc-1303	5	43	credited	credit	VERB
dpc-1303	5	44	.	.	PUNCT
dpc-1303	6	1	funding	funding	NOUN
dpc-1303	6	2	:	:	PUNCT
dpc-1303	6	3	this	this	DET
dpc-1303	6	4	study	study	NOUN
dpc-1303	6	5	was	be	AUX
dpc-1303	6	6	funded	fund	VERB
dpc-1303	6	7	and	and	CCONJ
dpc-1303	6	8	supported	support	VERB
dpc-1303	6	9	by	by	ADP
dpc-1303	6	10	tehran	tehran	PROPN
dpc-1303	6	11	university	university	PROPN
dpc-1303	6	12	of	of	ADP
dpc-1303	6	13	medical	medical	PROPN
dpc-1303	6	14	sciences	sciences	PROPN
dpc-1303	6	15	(	(	PUNCT
dpc-1303	6	16	tums	tum	NOUN
dpc-1303	6	17	)	)	PUNCT
dpc-1303	6	18	;	;	PUNCT
dpc-1303	6	19	grant	grant	VERB
dpc-1303	6	20	no	no	NOUN
dpc-1303	6	21	.	.	NOUN
dpc-1303	7	1	96	96	NUM
dpc-1303	7	2	-	-	PUNCT
dpc-1303	7	3	01	01	NUM
dpc-1303	7	4	-	-	PUNCT
dpc-1303	7	5	101	101	NUM
dpc-1303	7	6	-	-	PUNCT
dpc-1303	7	7	33881	33881	NUM
dpc-1303	7	8	.	.	PUNCT
dpc-1303	8	1	competing	compete	VERB
dpc-1303	8	2	interests	interest	NOUN
dpc-1303	8	3	:	:	PUNCT
dpc-1303	8	4	the	the	DET
dpc-1303	8	5	authors	author	NOUN
dpc-1303	8	6	have	have	VERB
dpc-1303	8	7	no	no	DET
dpc-1303	8	8	conflicts	conflict	NOUN
dpc-1303	8	9	of	of	ADP
dpc-1303	8	10	interest	interest	NOUN
dpc-1303	8	11	to	to	PART
dpc-1303	8	12	disclose	disclose	VERB
dpc-1303	8	13	.	.	PUNCT
dpc-1303	9	1	authorship	authorship	NOUN
dpc-1303	9	2	:	:	PUNCT
dpc-1303	9	3	all	all	DET
dpc-1303	9	4	authors	author	NOUN
dpc-1303	9	5	have	have	AUX
dpc-1303	9	6	contributed	contribute	VERB
dpc-1303	9	7	significantly	significantly	ADV
dpc-1303	9	8	to	to	ADP
dpc-1303	9	9	this	this	DET
dpc-1303	9	10	publication	publication	NOUN
dpc-1303	9	11	.	.	PUNCT
dpc-1303	10	1	corresponding	correspond	VERB
dpc-1303	10	2	author	author	NOUN
dpc-1303	10	3	:	:	PUNCT
dpc-1303	10	4	arghavan	arghavan	PROPN
dpc-1303	10	5	azizpour	azizpour	PROPN
dpc-1303	10	6	,	,	PUNCT
dpc-1303	10	7	md	md	PROPN
dpc-1303	10	8	,	,	PUNCT
dpc-1303	10	9	mph	mph	PROPN
dpc-1303	10	10	,	,	PUNCT
dpc-1303	10	11	tehran	tehran	PROPN
dpc-1303	10	12	university	university	PROPN
dpc-1303	10	13	of	of	ADP
dpc-1303	10	14	medical	medical	PROPN
dpc-1303	10	15	sciences	sciences	PROPN
dpc-1303	10	16	,	,	PUNCT
dpc-1303	10	17	razi	razi	PROPN
dpc-1303	10	18	hospital	hospital	PROPN
dpc-1303	10	19	,	,	PUNCT
dpc-1303	10	20	vahdat	vahdat	NOUN
dpc-1303	10	21	eslami	eslami	PROPN
dpc-1303	10	22	avenue	avenue	PROPN
dpc-1303	10	23	,	,	PUNCT
dpc-1303	10	24	tehran	tehran	PROPN
dpc-1303	10	25	,	,	PUNCT
dpc-1303	10	26	iran	iran	PROPN
dpc-1303	10	27	.	.	PUNCT
dpc-1303	11	1	email	email	NOUN
dpc-1303	11	2	:	:	PUNCT
dpc-1303	11	3	azizpour63@gmail.com	azizpour63@gmail.com	X
dpc-1303	11	4	background	background	NOUN
dpc-1303	11	5	:	:	PUNCT
dpc-1303	11	6	pemphigus	pemphigus	PROPN
dpc-1303	11	7	is	be	AUX
dpc-1303	11	8	a	a	DET
dpc-1303	11	9	rare	rare	ADJ
dpc-1303	11	10	group	group	NOUN
dpc-1303	11	11	of	of	ADP
dpc-1303	11	12	autoimmune	autoimmune	ADJ
dpc-1303	11	13	blistering	blister	VERB
dpc-1303	11	14	diseases	disease	NOUN
dpc-1303	11	15	with	with	ADP
dpc-1303	11	16	unknown	unknown	ADJ
dpc-1303	11	17	etiology	etiology	NOUN
dpc-1303	11	18	and	and	CCONJ
dpc-1303	11	19	unclear	unclear	ADJ
dpc-1303	11	20	pathogenesis	pathogenesis	NOUN
dpc-1303	11	21	.	.	PUNCT
dpc-1303	12	1	pemphigus	pemphigus	PROPN
dpc-1303	12	2	vulgaris	vulgaris	NOUN
dpc-1303	12	3	(	(	PUNCT
dpc-1303	12	4	pv	pv	NOUN
dpc-1303	12	5	)	)	PUNCT
dpc-1303	12	6	is	be	AUX
dpc-1303	12	7	the	the	DET
dpc-1303	12	8	most	most	ADV
dpc-1303	12	9	common	common	ADJ
dpc-1303	12	10	subtype	subtype	NOUN
dpc-1303	12	11	,	,	PUNCT
dpc-1303	12	12	and	and	CCONJ
dpc-1303	12	13	is	be	AUX
dpc-1303	12	14	characterized	characterize	VERB
dpc-1303	12	15	by	by	ADP
dpc-1303	12	16	ulcerations	ulceration	NOUN
dpc-1303	12	17	or	or	CCONJ
dpc-1303	12	18	flaccid	flaccid	ADJ
dpc-1303	12	19	blisters	blister	NOUN
dpc-1303	12	20	on	on	ADP
dpc-1303	12	21	mucous	mucous	ADJ
dpc-1303	12	22	membranes	membrane	NOUN
dpc-1303	12	23	and	and	CCONJ
dpc-1303	12	24	on	on	ADP
dpc-1303	12	25	the	the	DET
dpc-1303	12	26	skin	skin	NOUN
dpc-1303	12	27	.	.	PUNCT
dpc-1303	13	1	it	it	PRON
dpc-1303	13	2	is	be	AUX
dpc-1303	13	3	accepted	accept	VERB
dpc-1303	13	4	that	that	SCONJ
dpc-1303	13	5	cytokines	cytokine	NOUN
dpc-1303	13	6	have	have	VERB
dpc-1303	13	7	a	a	DET
dpc-1303	13	8	critical	critical	ADJ
dpc-1303	13	9	role	role	NOUN
dpc-1303	13	10	in	in	ADP
dpc-1303	13	11	the	the	DET
dpc-1303	13	12	pathogenesis	pathogenesis	NOUN
dpc-1303	13	13	of	of	ADP
dpc-1303	13	14	pv	pv	INTJ
dpc-1303	13	15	,	,	PUNCT
dpc-1303	13	16	while	while	SCONJ
dpc-1303	13	17	their	their	PRON
dpc-1303	13	18	exact	exact	ADJ
dpc-1303	13	19	roles	role	NOUN
dpc-1303	13	20	remain	remain	VERB
dpc-1303	13	21	to	to	PART
dpc-1303	13	22	be	be	AUX
dpc-1303	13	23	elucidated	elucidate	VERB
dpc-1303	13	24	.	.	PUNCT
dpc-1303	14	1	objectives	objective	NOUN
dpc-1303	14	2	:	:	PUNCT
dpc-1303	14	3	this	this	DET
dpc-1303	14	4	study	study	NOUN
dpc-1303	14	5	assessed	assess	VERB
dpc-1303	14	6	serum	serum	NOUN
dpc-1303	14	7	levels	level	NOUN
dpc-1303	14	8	of	of	ADP
dpc-1303	14	9	interleukin	interleukin	NOUN
dpc-1303	14	10	(	(	PUNCT
dpc-1303	14	11	il)-4	il)-4	NOUN
dpc-1303	14	12	and	and	CCONJ
dpc-1303	14	13	il-21	il-21	NOUN
dpc-1303	14	14	in	in	ADP
dpc-1303	14	15	different	different	ADJ
dpc-1303	14	16	phases	phase	NOUN
dpc-1303	14	17	of	of	ADP
dpc-1303	14	18	the	the	DET
dpc-1303	14	19	disease	disease	NOUN
dpc-1303	14	20	in	in	ADP
dpc-1303	14	21	comparison	comparison	NOUN
dpc-1303	14	22	with	with	ADP
dpc-1303	14	23	healthy	healthy	ADJ
dpc-1303	14	24	controls	control	NOUN
dpc-1303	14	25	.	.	PUNCT
dpc-1303	15	1	methods	method	NOUN
dpc-1303	15	2	:	:	PUNCT
dpc-1303	15	3	in	in	ADP
dpc-1303	15	4	a	a	DET
dpc-1303	15	5	case	case	NOUN
dpc-1303	15	6	-	-	PUNCT
dpc-1303	15	7	control	control	NOUN
dpc-1303	15	8	cohort	cohort	NOUN
dpc-1303	15	9	design	design	NOUN
dpc-1303	15	10	,	,	PUNCT
dpc-1303	15	11	serum	serum	NOUN
dpc-1303	15	12	levels	level	NOUN
dpc-1303	15	13	of	of	ADP
dpc-1303	15	14	il-4	il-4	NOUN
dpc-1303	15	15	and	and	CCONJ
dpc-1303	15	16	il-21	il-21	NOUN
dpc-1303	15	17	were	be	AUX
dpc-1303	15	18	determined	determine	VERB
dpc-1303	15	19	by	by	ADP
dpc-1303	15	20	elisa	elisa	NOUN
dpc-1303	15	21	in	in	ADP
dpc-1303	15	22	three	three	NUM
dpc-1303	15	23	groups	group	NOUN
dpc-1303	15	24	:	:	PUNCT
dpc-1303	15	25	patients	patient	NOUN
dpc-1303	15	26	with	with	ADP
dpc-1303	15	27	newly	newly	ADV
dpc-1303	15	28	diagnosed	diagnose	VERB
dpc-1303	15	29	pv	pv	NOUN
dpc-1303	15	30	,	,	PUNCT
dpc-1303	15	31	patients	patient	NOUN
dpc-1303	15	32	with	with	ADP
dpc-1303	15	33	chronic	chronic	ADJ
dpc-1303	15	34	,	,	PUNCT
dpc-1303	15	35	inactive	inactive	ADJ
dpc-1303	15	36	pv	pv	NOUN
dpc-1303	15	37	(	(	PUNCT
dpc-1303	15	38	pv	pv	INTJ
dpc-1303	15	39	in	in	ADP
dpc-1303	15	40	remission	remission	NOUN
dpc-1303	15	41	)	)	PUNCT
dpc-1303	15	42	,	,	PUNCT
dpc-1303	15	43	and	and	CCONJ
dpc-1303	15	44	healthy	healthy	ADJ
dpc-1303	15	45	controls	control	NOUN
dpc-1303	15	46	.	.	PUNCT
dpc-1303	16	1	results	result	NOUN
dpc-1303	16	2	:	:	PUNCT
dpc-1303	16	3	the	the	DET
dpc-1303	16	4	study	study	NOUN
dpc-1303	16	5	included	include	VERB
dpc-1303	16	6	88	88	NUM
dpc-1303	16	7	individuals	individual	NOUN
dpc-1303	16	8	(	(	PUNCT
dpc-1303	16	9	58	58	NUM
dpc-1303	16	10	women	woman	NOUN
dpc-1303	16	11	and	and	CCONJ
dpc-1303	16	12	30	30	NUM
dpc-1303	16	13	men	man	NOUN
dpc-1303	16	14	)	)	PUNCT
dpc-1303	16	15	,	,	PUNCT
dpc-1303	16	16	including	include	VERB
dpc-1303	16	17	26	26	NUM
dpc-1303	16	18	with	with	ADP
dpc-1303	16	19	newly	newly	ADV
dpc-1303	16	20	diagnosed	diagnose	VERB
dpc-1303	16	21	pv	pv	NOUN
dpc-1303	16	22	,	,	PUNCT
dpc-1303	16	23	33	33	NUM
dpc-1303	16	24	with	with	ADP
dpc-1303	16	25	pv	pv	NOUN
dpc-1303	16	26	in	in	ADP
dpc-1303	16	27	remission	remission	NOUN
dpc-1303	16	28	,	,	PUNCT
dpc-1303	16	29	and	and	CCONJ
dpc-1303	16	30	29	29	NUM
dpc-1303	16	31	healthy	healthy	ADJ
dpc-1303	16	32	controls	control	NOUN
dpc-1303	16	33	.	.	PUNCT
dpc-1303	17	1	a	a	DET
dpc-1303	17	2	significant	significant	ADJ
dpc-1303	17	3	difference	difference	NOUN
dpc-1303	17	4	was	be	AUX
dpc-1303	17	5	found	find	VERB
dpc-1303	17	6	among	among	ADP
dpc-1303	17	7	the	the	DET
dpc-1303	17	8	groups	group	NOUN
dpc-1303	17	9	for	for	ADP
dpc-1303	17	10	il-21	il-21	NOUN
dpc-1303	17	11	(	(	PUNCT
dpc-1303	17	12	p	p	X
dpc-1303	17	13	=	=	NOUN
dpc-1303	17	14	.044	.044	NUM
dpc-1303	17	15	)	)	PUNCT
dpc-1303	17	16	,	,	PUNCT
dpc-1303	17	17	but	but	CCONJ
dpc-1303	17	18	not	not	PART
dpc-1303	17	19	for	for	ADP
dpc-1303	17	20	il-4	il-4	NOUN
dpc-1303	17	21	(	(	PUNCT
dpc-1303	17	22	p	p	X
dpc-1303	17	23	=	=	NOUN
dpc-1303	17	24	.374	.374	NUM
dpc-1303	17	25	)	)	PUNCT
dpc-1303	17	26	.	.	PUNCT
dpc-1303	18	1	serum	serum	NOUN
dpc-1303	18	2	levels	level	NOUN
dpc-1303	18	3	of	of	ADP
dpc-1303	18	4	il-4	il-4	NOUN
dpc-1303	18	5	and	and	CCONJ
dpc-1303	18	6	il-21	il-21	NOUN
dpc-1303	18	7	in	in	ADP
dpc-1303	18	8	newly	newly	ADV
dpc-1303	18	9	diagnosed	diagnose	VERB
dpc-1303	18	10	patients	patient	NOUN
dpc-1303	18	11	were	be	AUX
dpc-1303	18	12	significantly	significantly	ADV
dpc-1303	18	13	lower	low	ADJ
dpc-1303	18	14	than	than	ADP
dpc-1303	18	15	in	in	ADP
dpc-1303	18	16	healthy	healthy	ADJ
dpc-1303	18	17	controls	control	NOUN
dpc-1303	18	18	(	(	PUNCT
dpc-1303	18	19	p	p	NOUN
dpc-1303	18	20	=	=	NOUN
dpc-1303	18	21	.005	.005	NUM
dpc-1303	18	22	for	for	ADP
dpc-1303	18	23	both	both	PRON
dpc-1303	18	24	)	)	PUNCT
dpc-1303	18	25	,	,	PUNCT
dpc-1303	18	26	but	but	CCONJ
dpc-1303	18	27	these	these	PRON
dpc-1303	18	28	cytoabstract	cytoabstract	VERB
dpc-1303	18	29	2	2	NUM
dpc-1303	18	30	research	research	NOUN
dpc-1303	18	31	|	|	ADV
dpc-1303	18	32	dermatol	dermatol	NOUN
dpc-1303	18	33	pract	pract	NOUN
dpc-1303	18	34	concept	concept	NOUN
dpc-1303	18	35	2021;11(2):e2021035	2021;11(2):e2021035	NUM
dpc-1303	18	36	introduction	introduction	NOUN
dpc-1303	18	37	pemphigus	pemphigus	NOUN
dpc-1303	18	38	is	be	AUX
dpc-1303	18	39	a	a	DET
dpc-1303	18	40	group	group	NOUN
dpc-1303	18	41	of	of	ADP
dpc-1303	18	42	potentially	potentially	ADV
dpc-1303	18	43	fatal	fatal	ADJ
dpc-1303	18	44	,	,	PUNCT
dpc-1303	18	45	chronic	chronic	ADJ
dpc-1303	18	46	,	,	PUNCT
dpc-1303	18	47	autoimmune	autoimmune	ADJ
dpc-1303	18	48	blistering	blister	VERB
dpc-1303	18	49	diseases	disease	NOUN
dpc-1303	18	50	affecting	affect	VERB
dpc-1303	18	51	the	the	DET
dpc-1303	18	52	skin	skin	NOUN
dpc-1303	18	53	and	and	CCONJ
dpc-1303	18	54	mucous	mucous	ADJ
dpc-1303	18	55	membranes	membrane	NOUN
dpc-1303	18	56	.	.	PUNCT
dpc-1303	19	1	although	although	SCONJ
dpc-1303	19	2	the	the	DET
dpc-1303	19	3	exact	exact	ADJ
dpc-1303	19	4	pathogenesis	pathogenesis	NOUN
dpc-1303	19	5	of	of	ADP
dpc-1303	19	6	this	this	DET
dpc-1303	19	7	disease	disease	NOUN
dpc-1303	19	8	is	be	AUX
dpc-1303	19	9	not	not	PART
dpc-1303	19	10	clearly	clearly	ADV
dpc-1303	19	11	understood	understand	VERB
dpc-1303	19	12	,	,	PUNCT
dpc-1303	19	13	it	it	PRON
dpc-1303	19	14	is	be	AUX
dpc-1303	19	15	accepted	accept	VERB
dpc-1303	19	16	that	that	SCONJ
dpc-1303	19	17	autoantibodies	autoantibody	NOUN
dpc-1303	19	18	against	against	ADP
dpc-1303	19	19	desmoglein	desmoglein	NOUN
dpc-1303	19	20	1	1	NUM
dpc-1303	19	21	(	(	PUNCT
dpc-1303	19	22	dsg1	dsg1	NOUN
dpc-1303	19	23	)	)	PUNCT
dpc-1303	19	24	and	and	CCONJ
dpc-1303	19	25	dsg3	dsg3	PROPN
dpc-1303	19	26	,	,	PUNCT
dpc-1303	19	27	produced	produce	VERB
dpc-1303	19	28	by	by	ADP
dpc-1303	19	29	b	b	PROPN
dpc-1303	19	30	cells	cell	NOUN
dpc-1303	19	31	,	,	PUNCT
dpc-1303	19	32	are	be	AUX
dpc-1303	19	33	the	the	DET
dpc-1303	19	34	main	main	ADJ
dpc-1303	19	35	cause	cause	NOUN
dpc-1303	19	36	of	of	ADP
dpc-1303	19	37	disease	disease	NOUN
dpc-1303	19	38	.	.	PUNCT
dpc-1303	20	1	in	in	ADP
dpc-1303	20	2	addition	addition	NOUN
dpc-1303	20	3	to	to	ADP
dpc-1303	20	4	b	b	NOUN
dpc-1303	20	5	cells	cell	NOUN
dpc-1303	20	6	,	,	PUNCT
dpc-1303	20	7	autoreactive	autoreactive	ADJ
dpc-1303	20	8	t	t	PROPN
dpc-1303	20	9	cells	cell	NOUN
dpc-1303	20	10	seem	seem	VERB
dpc-1303	20	11	to	to	PART
dpc-1303	20	12	be	be	AUX
dpc-1303	20	13	required	require	VERB
dpc-1303	20	14	in	in	ADP
dpc-1303	20	15	the	the	DET
dpc-1303	20	16	initial	initial	ADJ
dpc-1303	20	17	immunological	immunological	ADJ
dpc-1303	20	18	steps	step	NOUN
dpc-1303	20	19	for	for	ADP
dpc-1303	20	20	autoantibody	autoantibody	ADJ
dpc-1303	20	21	induction	induction	NOUN
dpc-1303	20	22	[	[	X
dpc-1303	20	23	1	1	NUM
dpc-1303	20	24	]	]	PUNCT
dpc-1303	20	25	.	.	PUNCT
dpc-1303	21	1	indeed	indeed	ADV
dpc-1303	21	2	,	,	PUNCT
dpc-1303	21	3	the	the	DET
dpc-1303	21	4	function	function	NOUN
dpc-1303	21	5	of	of	ADP
dpc-1303	21	6	some	some	DET
dpc-1303	21	7	t	t	NOUN
dpc-1303	21	8	cells	cell	NOUN
dpc-1303	21	9	is	be	AUX
dpc-1303	21	10	required	require	VERB
dpc-1303	21	11	for	for	ADP
dpc-1303	21	12	the	the	DET
dpc-1303	21	13	development	development	NOUN
dpc-1303	21	14	,	,	PUNCT
dpc-1303	21	15	function	function	NOUN
dpc-1303	21	16	,	,	PUNCT
dpc-1303	21	17	and	and	CCONJ
dpc-1303	21	18	antibody	antibody	NOUN
dpc-1303	21	19	production	production	NOUN
dpc-1303	21	20	of	of	ADP
dpc-1303	21	21	b	b	PROPN
dpc-1303	21	22	cells	cell	NOUN
dpc-1303	21	23	and	and	CCONJ
dpc-1303	21	24	plasma	plasma	NOUN
dpc-1303	21	25	cells	cell	NOUN
dpc-1303	21	26	during	during	ADP
dpc-1303	21	27	pemphigus	pemphigus	NOUN
dpc-1303	21	28	[	[	X
dpc-1303	21	29	2	2	NUM
dpc-1303	21	30	]	]	PUNCT
dpc-1303	21	31	.	.	PUNCT
dpc-1303	22	1	in	in	ADP
dpc-1303	22	2	contrast	contrast	NOUN
dpc-1303	22	3	,	,	PUNCT
dpc-1303	22	4	most	most	ADJ
dpc-1303	22	5	regulatory	regulatory	ADJ
dpc-1303	22	6	t	t	NOUN
dpc-1303	22	7	cells	cell	NOUN
dpc-1303	22	8	(	(	PUNCT
dpc-1303	22	9	tregs	treg	NOUN
dpc-1303	22	10	)	)	PUNCT
dpc-1303	22	11	can	can	AUX
dpc-1303	22	12	negatively	negatively	ADV
dpc-1303	22	13	influence	influence	VERB
dpc-1303	22	14	b	b	PRON
dpc-1303	22	15	cell	cell	NOUN
dpc-1303	22	16	differentiation	differentiation	NOUN
dpc-1303	22	17	and	and	CCONJ
dpc-1303	22	18	function	function	NOUN
dpc-1303	22	19	.	.	PUNCT
dpc-1303	23	1	t	t	NOUN
dpc-1303	23	2	cells	cell	NOUN
dpc-1303	23	3	,	,	PUNCT
dpc-1303	23	4	which	which	PRON
dpc-1303	23	5	are	be	AUX
dpc-1303	23	6	sources	source	NOUN
dpc-1303	23	7	of	of	ADP
dpc-1303	23	8	several	several	ADJ
dpc-1303	23	9	cytokines	cytokine	NOUN
dpc-1303	23	10	and	and	CCONJ
dpc-1303	23	11	chemokines	chemokine	NOUN
dpc-1303	23	12	,	,	PUNCT
dpc-1303	23	13	not	not	PART
dpc-1303	23	14	only	only	ADV
dpc-1303	23	15	affect	affect	VERB
dpc-1303	23	16	other	other	ADJ
dpc-1303	23	17	immune	immune	ADJ
dpc-1303	23	18	cells	cell	NOUN
dpc-1303	23	19	belonging	belong	VERB
dpc-1303	23	20	to	to	ADP
dpc-1303	23	21	the	the	DET
dpc-1303	23	22	innate	innate	ADJ
dpc-1303	23	23	and	and	CCONJ
dpc-1303	23	24	adaptive	adaptive	ADJ
dpc-1303	23	25	immune	immune	ADJ
dpc-1303	23	26	systems	system	NOUN
dpc-1303	23	27	,	,	PUNCT
dpc-1303	23	28	but	but	CCONJ
dpc-1303	23	29	also	also	ADV
dpc-1303	23	30	can	can	AUX
dpc-1303	23	31	act	act	VERB
dpc-1303	23	32	in	in	ADP
dpc-1303	23	33	an	an	DET
dpc-1303	23	34	autocrine	autocrine	NOUN
dpc-1303	23	35	manner	manner	NOUN
dpc-1303	23	36	.	.	PUNCT
dpc-1303	24	1	several	several	ADJ
dpc-1303	24	2	cytokines	cytokine	NOUN
dpc-1303	24	3	have	have	AUX
dpc-1303	24	4	been	be	AUX
dpc-1303	24	5	studied	study	VERB
dpc-1303	24	6	in	in	ADP
dpc-1303	24	7	pemphigus	pemphigus	NOUN
dpc-1303	24	8	patients	patient	NOUN
dpc-1303	24	9	so	so	ADV
dpc-1303	24	10	far	far	ADV
dpc-1303	24	11	[	[	X
dpc-1303	24	12	3,4	3,4	NUM
dpc-1303	24	13	]	]	PUNCT
dpc-1303	24	14	.	.	PUNCT
dpc-1303	25	1	some	some	PRON
dpc-1303	25	2	of	of	ADP
dpc-1303	25	3	these	these	DET
dpc-1303	25	4	cytokines	cytokine	NOUN
dpc-1303	25	5	,	,	PUNCT
dpc-1303	25	6	such	such	ADJ
dpc-1303	25	7	as	as	ADP
dpc-1303	25	8	interleukin	interleukin	NOUN
dpc-1303	25	9	(	(	PUNCT
dpc-1303	25	10	il)-4	il)-4	VERB
dpc-1303	25	11	,	,	PUNCT
dpc-1303	25	12	are	be	AUX
dpc-1303	25	13	believed	believe	VERB
dpc-1303	25	14	to	to	PART
dpc-1303	25	15	be	be	AUX
dpc-1303	25	16	pathogenic	pathogenic	ADJ
dpc-1303	25	17	[	[	X
dpc-1303	25	18	5	5	NUM
dpc-1303	25	19	]	]	PUNCT
dpc-1303	25	20	and	and	CCONJ
dpc-1303	25	21	some	some	DET
dpc-1303	25	22	others	other	NOUN
dpc-1303	25	23	,	,	PUNCT
dpc-1303	25	24	such	such	ADJ
dpc-1303	25	25	as	as	ADP
dpc-1303	25	26	il-10	il-10	PRON
dpc-1303	25	27	,	,	PUNCT
dpc-1303	25	28	could	could	AUX
dpc-1303	25	29	be	be	AUX
dpc-1303	25	30	a	a	DET
dpc-1303	25	31	double	double	ADJ
dpc-1303	25	32	-	-	PUNCT
dpc-1303	25	33	edged	edge	VERB
dpc-1303	25	34	sword	sword	NOUN
dpc-1303	26	1	[	[	X
dpc-1303	26	2	6	6	NUM
dpc-1303	26	3	]	]	PUNCT
dpc-1303	26	4	.	.	PUNCT
dpc-1303	27	1	regarding	regard	VERB
dpc-1303	27	2	the	the	DET
dpc-1303	27	3	roles	role	NOUN
dpc-1303	27	4	of	of	ADP
dpc-1303	27	5	some	some	DET
dpc-1303	27	6	other	other	ADJ
dpc-1303	27	7	newly	newly	ADV
dpc-1303	27	8	identified	identify	VERB
dpc-1303	27	9	,	,	PUNCT
dpc-1303	27	10	less	less	ADV
dpc-1303	27	11	studied	studied	ADJ
dpc-1303	27	12	cytokines	cytokine	NOUN
dpc-1303	27	13	,	,	PUNCT
dpc-1303	27	14	such	such	ADJ
dpc-1303	27	15	as	as	ADP
dpc-1303	27	16	il-21	il-21	NUM
dpc-1303	27	17	and	and	CCONJ
dpc-1303	27	18	il-35	il-35	PRON
dpc-1303	27	19	,	,	PUNCT
dpc-1303	27	20	it	it	PRON
dpc-1303	27	21	is	be	AUX
dpc-1303	27	22	hard	hard	ADJ
dpc-1303	27	23	to	to	PART
dpc-1303	27	24	judge	judge	VERB
dpc-1303	27	25	,	,	PUNCT
dpc-1303	27	26	but	but	CCONJ
dpc-1303	27	27	they	they	PRON
dpc-1303	27	28	are	be	AUX
dpc-1303	27	29	probably	probably	ADV
dpc-1303	27	30	pathogenic	pathogenic	ADJ
dpc-1303	27	31	and	and	CCONJ
dpc-1303	27	32	protective	protective	ADJ
dpc-1303	27	33	,	,	PUNCT
dpc-1303	27	34	respectively	respectively	ADV
dpc-1303	27	35	[	[	X
dpc-1303	27	36	7,8	7,8	NUM
dpc-1303	27	37	]	]	PUNCT
dpc-1303	27	38	.	.	PUNCT
dpc-1303	28	1	in	in	ADP
dpc-1303	28	2	addition	addition	NOUN
dpc-1303	28	3	to	to	ADP
dpc-1303	28	4	indirect	indirect	ADJ
dpc-1303	28	5	roles	role	NOUN
dpc-1303	28	6	of	of	ADP
dpc-1303	28	7	t	t	NOUN
dpc-1303	28	8	cells	cell	NOUN
dpc-1303	28	9	in	in	ADP
dpc-1303	28	10	the	the	DET
dpc-1303	28	11	pathogenesis	pathogenesis	NOUN
dpc-1303	28	12	of	of	ADP
dpc-1303	28	13	pemphigus	pemphigus	NOUN
dpc-1303	28	14	,	,	PUNCT
dpc-1303	28	15	direct	direct	ADJ
dpc-1303	28	16	recognition	recognition	NOUN
dpc-1303	28	17	of	of	ADP
dpc-1303	28	18	anti	anti	ADJ
dpc-1303	28	19	-	-	ADJ
dpc-1303	28	20	dsg3	dsg3	ADJ
dpc-1303	28	21	by	by	ADP
dpc-1303	28	22	dsg3	dsg3	PROPN
dpc-1303	28	23	-	-	PUNCT
dpc-1303	28	24	specific	specific	NOUN
dpc-1303	28	25	cd4	cd4	PROPN
dpc-1303	28	26	+	+	PROPN
dpc-1303	28	27	t	t	PROPN
dpc-1303	28	28	helper	helper	NOUN
dpc-1303	28	29	cells	cell	NOUN
dpc-1303	28	30	has	have	AUX
dpc-1303	28	31	been	be	AUX
dpc-1303	28	32	suggested	suggest	VERB
dpc-1303	28	33	[	[	PUNCT
dpc-1303	28	34	9	9	NUM
dpc-1303	28	35	-	-	SYM
dpc-1303	28	36	11	11	NUM
dpc-1303	28	37	]	]	PUNCT
dpc-1303	28	38	.	.	PUNCT
dpc-1303	29	1	to	to	ADP
dpc-1303	29	2	date	date	NOUN
dpc-1303	29	3	,	,	PUNCT
dpc-1303	29	4	several	several	ADJ
dpc-1303	29	5	subsets	subset	NOUN
dpc-1303	29	6	of	of	ADP
dpc-1303	29	7	t	t	PROPN
dpc-1303	29	8	helper	helper	NOUN
dpc-1303	29	9	(	(	PUNCT
dpc-1303	29	10	th	th	NOUN
dpc-1303	29	11	)	)	PUNCT
dpc-1303	29	12	cells	cell	NOUN
dpc-1303	29	13	have	have	AUX
dpc-1303	29	14	been	be	AUX
dpc-1303	29	15	identified	identify	VERB
dpc-1303	29	16	.	.	PUNCT
dpc-1303	30	1	these	these	DET
dpc-1303	30	2	subsets	subset	NOUN
dpc-1303	30	3	,	,	PUNCT
dpc-1303	30	4	which	which	PRON
dpc-1303	30	5	include	include	VERB
dpc-1303	30	6	th1	th1	PROPN
dpc-1303	30	7	,	,	PUNCT
dpc-1303	30	8	th2	th2	PROPN
dpc-1303	30	9	,	,	PUNCT
dpc-1303	30	10	th9	th9	PROPN
dpc-1303	30	11	,	,	PUNCT
dpc-1303	30	12	th17	th17	PROPN
dpc-1303	30	13	,	,	PUNCT
dpc-1303	30	14	th22	th22	PROPN
dpc-1303	30	15	,	,	PUNCT
dpc-1303	30	16	follicular	follicular	ADJ
dpc-1303	30	17	t	t	NOUN
dpc-1303	30	18	helper	helper	NOUN
dpc-1303	30	19	(	(	PUNCT
dpc-1303	30	20	tfh	tfh	NOUN
dpc-1303	30	21	)	)	PUNCT
dpc-1303	30	22	,	,	PUNCT
dpc-1303	30	23	and	and	CCONJ
dpc-1303	30	24	treg	treg	PROPN
dpc-1303	30	25	subpopulations	subpopulation	NOUN
dpc-1303	30	26	,	,	PUNCT
dpc-1303	30	27	could	could	AUX
dpc-1303	30	28	reciprocally	reciprocally	ADV
dpc-1303	30	29	regulate	regulate	VERB
dpc-1303	30	30	each	each	DET
dpc-1303	30	31	other	other	ADJ
dpc-1303	30	32	.	.	PUNCT
dpc-1303	31	1	previously	previously	ADV
dpc-1303	31	2	,	,	PUNCT
dpc-1303	31	3	pemphigus	pemphigus	PROPN
dpc-1303	31	4	used	use	VERB
dpc-1303	31	5	to	to	PART
dpc-1303	31	6	be	be	AUX
dpc-1303	31	7	known	know	VERB
dpc-1303	31	8	as	as	ADP
dpc-1303	31	9	a	a	DET
dpc-1303	31	10	th-2	th-2	PRON
dpc-1303	31	11	dominant	dominant	ADJ
dpc-1303	31	12	disease	disease	NOUN
dpc-1303	31	13	,	,	PUNCT
dpc-1303	31	14	while	while	SCONJ
dpc-1303	31	15	increasing	increase	VERB
dpc-1303	31	16	pieces	piece	NOUN
dpc-1303	31	17	of	of	ADP
dpc-1303	31	18	evidence	evidence	NOUN
dpc-1303	31	19	are	be	AUX
dpc-1303	31	20	suggesting	suggest	VERB
dpc-1303	31	21	a	a	DET
dpc-1303	31	22	critical	critical	ADJ
dpc-1303	31	23	role	role	NOUN
dpc-1303	31	24	of	of	ADP
dpc-1303	31	25	other	other	ADJ
dpc-1303	31	26	subsets	subset	NOUN
dpc-1303	31	27	,	,	PUNCT
dpc-1303	31	28	such	such	ADJ
dpc-1303	31	29	as	as	ADP
dpc-1303	31	30	th17	th17	PROPN
dpc-1303	31	31	and	and	CCONJ
dpc-1303	31	32	tfh	tfh	NOUN
dpc-1303	32	1	[	[	X
dpc-1303	32	2	12	12	NUM
dpc-1303	32	3	-	-	SYM
dpc-1303	32	4	14	14	NUM
dpc-1303	32	5	]	]	PUNCT
dpc-1303	32	6	.	.	PUNCT
dpc-1303	33	1	as	as	SCONJ
dpc-1303	33	2	already	already	ADV
dpc-1303	33	3	mentioned	mention	VERB
dpc-1303	33	4	,	,	PUNCT
dpc-1303	33	5	cytokines	cytokine	NOUN
dpc-1303	33	6	do	do	AUX
dpc-1303	33	7	not	not	PART
dpc-1303	33	8	only	only	ADV
dpc-1303	33	9	affect	affect	VERB
dpc-1303	33	10	b	b	NOUN
dpc-1303	33	11	cells	cell	NOUN
dpc-1303	33	12	,	,	PUNCT
dpc-1303	33	13	but	but	CCONJ
dpc-1303	33	14	could	could	AUX
dpc-1303	33	15	also	also	ADV
dpc-1303	33	16	affect	affect	VERB
dpc-1303	33	17	other	other	ADJ
dpc-1303	33	18	th	th	NUM
dpc-1303	33	19	cells	cell	NOUN
dpc-1303	33	20	.	.	PUNCT
dpc-1303	34	1	il-4	il-4	NOUN
dpc-1303	35	1	and	and	CCONJ
dpc-1303	35	2	il-21	il-21	NOUN
dpc-1303	35	3	are	be	AUX
dpc-1303	35	4	2	2	NUM
dpc-1303	35	5	critical	critical	ADJ
dpc-1303	35	6	cytokines	cytokine	NOUN
dpc-1303	35	7	involved	involve	VERB
dpc-1303	35	8	in	in	ADP
dpc-1303	35	9	the	the	DET
dpc-1303	35	10	differentiation	differentiation	NOUN
dpc-1303	35	11	of	of	ADP
dpc-1303	35	12	naïve	naïve	ADJ
dpc-1303	35	13	th	th	X
dpc-1303	35	14	cells	cell	NOUN
dpc-1303	35	15	into	into	ADP
dpc-1303	35	16	th2	th2	PROPN
dpc-1303	35	17	and	and	CCONJ
dpc-1303	35	18	th17	th17	PROPN
dpc-1303	35	19	,	,	PUNCT
dpc-1303	35	20	respectively	respectively	ADV
dpc-1303	35	21	.	.	PUNCT
dpc-1303	36	1	additionally	additionally	ADV
dpc-1303	36	2	,	,	PUNCT
dpc-1303	36	3	il-21	il-21	PRON
dpc-1303	36	4	seems	seem	VERB
dpc-1303	36	5	to	to	PART
dpc-1303	36	6	be	be	AUX
dpc-1303	36	7	essential	essential	ADJ
dpc-1303	36	8	for	for	ADP
dpc-1303	36	9	tfh	tfh	PROPN
dpc-1303	36	10	development	development	NOUN
dpc-1303	37	1	[	[	X
dpc-1303	37	2	7	7	NUM
dpc-1303	37	3	]	]	PUNCT
dpc-1303	37	4	.	.	PUNCT
dpc-1303	38	1	to	to	ADP
dpc-1303	38	2	date	date	NOUN
dpc-1303	38	3	,	,	PUNCT
dpc-1303	38	4	different	different	ADJ
dpc-1303	38	5	studies	study	NOUN
dpc-1303	38	6	have	have	AUX
dpc-1303	38	7	explored	explore	VERB
dpc-1303	38	8	the	the	DET
dpc-1303	38	9	role	role	NOUN
dpc-1303	38	10	of	of	ADP
dpc-1303	38	11	il-4	il-4	NOUN
dpc-1303	38	12	,	,	PUNCT
dpc-1303	38	13	and	and	CCONJ
dpc-1303	38	14	the	the	DET
dpc-1303	38	15	majority	majority	NOUN
dpc-1303	38	16	of	of	ADP
dpc-1303	38	17	them	they	PRON
dpc-1303	38	18	are	be	AUX
dpc-1303	38	19	consistent	consistent	ADJ
dpc-1303	38	20	with	with	ADP
dpc-1303	38	21	the	the	DET
dpc-1303	38	22	suggested	suggest	VERB
dpc-1303	38	23	pathogenic	pathogenic	ADJ
dpc-1303	38	24	role	role	NOUN
dpc-1303	38	25	of	of	ADP
dpc-1303	38	26	this	this	DET
dpc-1303	38	27	cytokine	cytokine	NOUN
dpc-1303	38	28	.	.	PUNCT
dpc-1303	39	1	il-4	il-4	PUNCT
dpc-1303	39	2	is	be	AUX
dpc-1303	39	3	mainly	mainly	ADV
dpc-1303	39	4	produced	produce	VERB
dpc-1303	39	5	by	by	ADP
dpc-1303	39	6	th2	th2	PROPN
dpc-1303	39	7	cells	cell	NOUN
dpc-1303	39	8	and	and	CCONJ
dpc-1303	39	9	causes	cause	VERB
dpc-1303	39	10	th2	th2	PROPN
dpc-1303	39	11	cell	cell	NOUN
dpc-1303	39	12	differentiation	differentiation	NOUN
dpc-1303	39	13	in	in	ADP
dpc-1303	39	14	an	an	DET
dpc-1303	39	15	autocrine	autocrine	NOUN
dpc-1303	39	16	manner	manner	NOUN
dpc-1303	39	17	.	.	PUNCT
dpc-1303	40	1	additionally	additionally	ADV
dpc-1303	40	2	,	,	PUNCT
dpc-1303	40	3	it	it	PRON
dpc-1303	40	4	induces	induce	VERB
dpc-1303	40	5	isotype	isotype	NOUN
dpc-1303	40	6	switching	switching	NOUN
dpc-1303	40	7	toward	toward	ADP
dpc-1303	40	8	igg4	igg4	NOUN
dpc-1303	40	9	,	,	PUNCT
dpc-1303	40	10	a	a	DET
dpc-1303	40	11	well	well	ADV
dpc-1303	40	12	-	-	PUNCT
dpc-1303	40	13	recognized	recognize	VERB
dpc-1303	40	14	class	class	NOUN
dpc-1303	40	15	of	of	ADP
dpc-1303	40	16	igg	igg	PROPN
dpc-1303	40	17	antibodies	antibody	NOUN
dpc-1303	40	18	involved	involve	VERB
dpc-1303	40	19	in	in	ADP
dpc-1303	40	20	pemphigus	pemphigus	NOUN
dpc-1303	40	21	[	[	X
dpc-1303	40	22	15	15	NUM
dpc-1303	40	23	]	]	PUNCT
dpc-1303	40	24	.	.	PUNCT
dpc-1303	41	1	il-21	il-21	PUNCT
dpc-1303	41	2	is	be	AUX
dpc-1303	41	3	another	another	DET
dpc-1303	41	4	critical	critical	ADJ
dpc-1303	41	5	cytokine	cytokine	NOUN
dpc-1303	41	6	in	in	ADP
dpc-1303	41	7	the	the	DET
dpc-1303	41	8	immune	immune	ADJ
dpc-1303	41	9	system	system	NOUN
dpc-1303	41	10	that	that	PRON
dpc-1303	41	11	plays	play	VERB
dpc-1303	41	12	a	a	DET
dpc-1303	41	13	role	role	NOUN
dpc-1303	41	14	in	in	ADP
dpc-1303	41	15	the	the	DET
dpc-1303	41	16	pathogenesis	pathogenesis	NOUN
dpc-1303	41	17	of	of	ADP
dpc-1303	41	18	immune	immune	NOUN
dpc-1303	41	19	-	-	PUNCT
dpc-1303	41	20	mediated	mediate	VERB
dpc-1303	41	21	diseases	disease	NOUN
dpc-1303	41	22	.	.	PUNCT
dpc-1303	42	1	it	it	PRON
dpc-1303	42	2	is	be	AUX
dpc-1303	42	3	mainly	mainly	ADV
dpc-1303	42	4	produced	produce	VERB
dpc-1303	42	5	by	by	ADP
dpc-1303	42	6	natural	natural	ADJ
dpc-1303	42	7	killer	killer	PROPN
dpc-1303	42	8	t	t	PROPN
dpc-1303	42	9	,	,	PUNCT
dpc-1303	42	10	th17	th17	PROPN
dpc-1303	42	11	,	,	PUNCT
dpc-1303	42	12	and	and	CCONJ
dpc-1303	42	13	tfh	tfh	NUM
dpc-1303	42	14	cells	cell	NOUN
dpc-1303	42	15	.	.	PUNCT
dpc-1303	43	1	it	it	PRON
dpc-1303	43	2	leads	lead	VERB
dpc-1303	43	3	to	to	ADP
dpc-1303	43	4	the	the	DET
dpc-1303	43	5	promotion	promotion	NOUN
dpc-1303	43	6	of	of	ADP
dpc-1303	43	7	cd4	cd4	PROPN
dpc-1303	43	8	+	+	PROPN
dpc-1303	43	9	t	t	NOUN
dpc-1303	43	10	cells	cell	NOUN
dpc-1303	43	11	,	,	PUNCT
dpc-1303	43	12	including	include	VERB
dpc-1303	43	13	th2	th2	PROPN
dpc-1303	43	14	,	,	PUNCT
dpc-1303	43	15	th17	th17	PROPN
dpc-1303	43	16	,	,	PUNCT
dpc-1303	43	17	and	and	CCONJ
dpc-1303	43	18	tfh	tfh	NUM
dpc-1303	43	19	cells	cell	NOUN
dpc-1303	43	20	;	;	PUNCT
dpc-1303	43	21	cd8	cd8	PROPN
dpc-1303	43	22	+	+	PROPN
dpc-1303	43	23	cytotoxic	cytotoxic	ADJ
dpc-1303	43	24	t	t	NOUN
dpc-1303	43	25	lymphocytes	lymphocyte	NOUN
dpc-1303	43	26	are	be	AUX
dpc-1303	43	27	also	also	ADV
dpc-1303	43	28	affected	affect	VERB
dpc-1303	43	29	by	by	ADP
dpc-1303	43	30	il-21	il-21	PRON
dpc-1303	43	31	[	[	X
dpc-1303	43	32	7	7	NUM
dpc-1303	43	33	]	]	PUNCT
dpc-1303	43	34	.	.	PUNCT
dpc-1303	44	1	it	it	PRON
dpc-1303	44	2	also	also	ADV
dpc-1303	44	3	causes	cause	VERB
dpc-1303	44	4	the	the	DET
dpc-1303	44	5	production	production	NOUN
dpc-1303	44	6	of	of	ADP
dpc-1303	44	7	igg	igg	PROPN
dpc-1303	44	8	in	in	ADP
dpc-1303	44	9	addition	addition	NOUN
dpc-1303	44	10	to	to	ADP
dpc-1303	44	11	negatively	negatively	ADV
dpc-1303	44	12	affecting	affect	VERB
dpc-1303	44	13	tregs	treg	NOUN
dpc-1303	44	14	.	.	PUNCT
dpc-1303	45	1	in	in	ADP
dpc-1303	45	2	this	this	DET
dpc-1303	45	3	study	study	NOUN
dpc-1303	45	4	,	,	PUNCT
dpc-1303	45	5	we	we	PRON
dpc-1303	45	6	evaluated	evaluate	VERB
dpc-1303	45	7	serum	serum	NOUN
dpc-1303	45	8	levels	level	NOUN
dpc-1303	45	9	of	of	ADP
dpc-1303	45	10	il-4	il-4	NOUN
dpc-1303	45	11	and	and	CCONJ
dpc-1303	45	12	il-21	il-21	X
dpc-1303	45	13	in	in	ADP
dpc-1303	45	14	2	2	NUM
dpc-1303	45	15	groups	group	NOUN
dpc-1303	45	16	of	of	ADP
dpc-1303	45	17	patients	patient	NOUN
dpc-1303	45	18	with	with	ADP
dpc-1303	45	19	pemphigus	pemphigus	ADJ
dpc-1303	45	20	vulgaris	vulgaris	NOUN
dpc-1303	45	21	(	(	PUNCT
dpc-1303	45	22	pv	pv	NOUN
dpc-1303	45	23	)	)	PUNCT
dpc-1303	45	24	,	,	PUNCT
dpc-1303	45	25	including	include	VERB
dpc-1303	45	26	newly	newly	ADV
dpc-1303	45	27	diagnosed	diagnose	VERB
dpc-1303	45	28	patients	patient	NOUN
dpc-1303	45	29	with	with	ADP
dpc-1303	45	30	active	active	ADJ
dpc-1303	45	31	disease	disease	NOUN
dpc-1303	45	32	and	and	CCONJ
dpc-1303	45	33	patients	patient	NOUN
dpc-1303	45	34	with	with	ADP
dpc-1303	45	35	chronic	chronic	ADJ
dpc-1303	45	36	,	,	PUNCT
dpc-1303	45	37	inactive	inactive	ADJ
dpc-1303	45	38	disease	disease	NOUN
dpc-1303	45	39	,	,	PUNCT
dpc-1303	45	40	and	and	CCONJ
dpc-1303	45	41	compared	compare	VERB
dpc-1303	45	42	them	they	PRON
dpc-1303	45	43	with	with	ADP
dpc-1303	45	44	healthy	healthy	ADJ
dpc-1303	45	45	controls	control	NOUN
dpc-1303	45	46	.	.	PUNCT
dpc-1303	46	1	materials	material	NOUN
dpc-1303	46	2	and	and	CCONJ
dpc-1303	46	3	methods	method	NOUN
dpc-1303	46	4	study	study	NOUN
dpc-1303	46	5	design	design	NOUN
dpc-1303	46	6	and	and	CCONJ
dpc-1303	46	7	inclusion	inclusion	NOUN
dpc-1303	46	8	criteria	criterion	NOUN
dpc-1303	46	9	during	during	ADP
dpc-1303	46	10	a	a	DET
dpc-1303	46	11	2	2	NUM
dpc-1303	46	12	-	-	PUNCT
dpc-1303	46	13	year	year	NOUN
dpc-1303	46	14	period	period	NOUN
dpc-1303	46	15	(	(	PUNCT
dpc-1303	46	16	2016	2016	NUM
dpc-1303	46	17	-	-	SYM
dpc-1303	46	18	2018	2018	NUM
dpc-1303	46	19	)	)	PUNCT
dpc-1303	46	20	,	,	PUNCT
dpc-1303	46	21	patients	patient	NOUN
dpc-1303	46	22	with	with	ADP
dpc-1303	46	23	newly	newly	ADV
dpc-1303	46	24	diagnosed	diagnose	VERB
dpc-1303	46	25	pv	pv	NOUN
dpc-1303	46	26	at	at	ADP
dpc-1303	46	27	the	the	DET
dpc-1303	46	28	department	department	NOUN
dpc-1303	46	29	of	of	ADP
dpc-1303	46	30	dermatology	dermatology	NOUN
dpc-1303	46	31	at	at	ADP
dpc-1303	46	32	razi	razi	PROPN
dpc-1303	46	33	hospital	hospital	PROPN
dpc-1303	46	34	who	who	PRON
dpc-1303	46	35	met	meet	VERB
dpc-1303	46	36	the	the	DET
dpc-1303	46	37	inclusion	inclusion	NOUN
dpc-1303	46	38	criteria	criterion	NOUN
dpc-1303	46	39	(	(	PUNCT
dpc-1303	46	40	see	see	VERB
dpc-1303	46	41	below	below	ADV
dpc-1303	46	42	)	)	PUNCT
dpc-1303	46	43	were	be	AUX
dpc-1303	46	44	included	include	VERB
dpc-1303	46	45	in	in	ADP
dpc-1303	46	46	the	the	DET
dpc-1303	46	47	study	study	NOUN
dpc-1303	46	48	(	(	PUNCT
dpc-1303	46	49	newly	newly	ADV
dpc-1303	46	50	diagnosed	diagnose	VERB
dpc-1303	46	51	pv	pv	NOUN
dpc-1303	46	52	group	group	NOUN
dpc-1303	46	53	)	)	PUNCT
dpc-1303	46	54	.	.	PUNCT
dpc-1303	47	1	additionally	additionally	ADV
dpc-1303	47	2	,	,	PUNCT
dpc-1303	47	3	patients	patient	NOUN
dpc-1303	47	4	with	with	ADP
dpc-1303	47	5	chronic	chronic	ADJ
dpc-1303	47	6	but	but	CCONJ
dpc-1303	47	7	inactive	inactive	ADJ
dpc-1303	47	8	pv	pv	NOUN
dpc-1303	47	9	(	(	PUNCT
dpc-1303	47	10	pv	pv	NOUN
dpc-1303	47	11	in	in	ADP
dpc-1303	47	12	remission	remission	NOUN
dpc-1303	47	13	group	group	NOUN
dpc-1303	47	14	)	)	PUNCT
dpc-1303	47	15	as	as	ADV
dpc-1303	47	16	well	well	ADV
dpc-1303	47	17	as	as	ADP
dpc-1303	47	18	a	a	DET
dpc-1303	47	19	similar	similar	ADJ
dpc-1303	47	20	number	number	NOUN
dpc-1303	47	21	of	of	ADP
dpc-1303	47	22	matched	match	VERB
dpc-1303	47	23	healthy	healthy	ADJ
dpc-1303	47	24	controls	control	NOUN
dpc-1303	47	25	were	be	AUX
dpc-1303	47	26	included	include	VERB
dpc-1303	47	27	.	.	PUNCT
dpc-1303	48	1	before	before	ADP
dpc-1303	48	2	inclusion	inclusion	NOUN
dpc-1303	48	3	,	,	PUNCT
dpc-1303	48	4	all	all	DET
dpc-1303	48	5	patients	patient	NOUN
dpc-1303	48	6	were	be	AUX
dpc-1303	48	7	examined	examine	VERB
dpc-1303	48	8	by	by	ADP
dpc-1303	48	9	at	at	ADV
dpc-1303	48	10	least	least	ADJ
dpc-1303	48	11	1	1	NUM
dpc-1303	48	12	dermatologist	dermatologist	NOUN
dpc-1303	48	13	,	,	PUNCT
dpc-1303	48	14	and	and	CCONJ
dpc-1303	48	15	the	the	DET
dpc-1303	48	16	diagnosis	diagnosis	NOUN
dpc-1303	48	17	of	of	ADP
dpc-1303	48	18	pv	pv	NOUN
dpc-1303	48	19	was	be	AUX
dpc-1303	48	20	confirmed	confirm	VERB
dpc-1303	48	21	based	base	VERB
dpc-1303	48	22	on	on	ADP
dpc-1303	48	23	clinical	clinical	ADJ
dpc-1303	48	24	features	feature	NOUN
dpc-1303	48	25	,	,	PUNCT
dpc-1303	48	26	detectable	detectable	ADJ
dpc-1303	48	27	autoantibodies	autoantibody	NOUN
dpc-1303	48	28	against	against	ADP
dpc-1303	48	29	dsg1	dsg1	NOUN
dpc-1303	48	30	or	or	CCONJ
dpc-1303	48	31	dsg3	dsg3	PROPN
dpc-1303	48	32	,	,	PUNCT
dpc-1303	48	33	histopathology	histopathology	NOUN
dpc-1303	48	34	,	,	PUNCT
dpc-1303	48	35	and	and	CCONJ
dpc-1303	48	36	positive	positive	ADJ
dpc-1303	48	37	perilesional	perilesional	ADJ
dpc-1303	48	38	direct	direct	ADJ
dpc-1303	48	39	immunofluorescence	immunofluorescence	NOUN
dpc-1303	48	40	studies	study	NOUN
dpc-1303	48	41	.	.	PUNCT
dpc-1303	49	1	patient	patient	ADJ
dpc-1303	49	2	selection	selection	NOUN
dpc-1303	49	3	and	and	CCONJ
dpc-1303	49	4	cytokine	cytokine	NOUN
dpc-1303	49	5	assay	assay	VERB
dpc-1303	49	6	the	the	DET
dpc-1303	49	7	inclusion	inclusion	NOUN
dpc-1303	49	8	criteria	criterion	NOUN
dpc-1303	49	9	for	for	ADP
dpc-1303	49	10	patients	patient	NOUN
dpc-1303	49	11	were	be	AUX
dpc-1303	49	12	:	:	PUNCT
dpc-1303	49	13	(	(	PUNCT
dpc-1303	49	14	1	1	X
dpc-1303	49	15	)	)	PUNCT
dpc-1303	49	16	confirmed	confirm	VERB
dpc-1303	49	17	diagnosis	diagnosis	NOUN
dpc-1303	49	18	of	of	ADP
dpc-1303	49	19	pv	pv	INTJ
dpc-1303	49	20	,	,	PUNCT
dpc-1303	49	21	(	(	PUNCT
dpc-1303	49	22	2	2	X
dpc-1303	49	23	)	)	PUNCT
dpc-1303	49	24	treatment	treatment	NOUN
dpc-1303	49	25	-	-	PUNCT
dpc-1303	49	26	naïve	naïve	ADJ
dpc-1303	49	27	status	status	NOUN
dpc-1303	49	28	for	for	ADP
dpc-1303	49	29	new	new	ADJ
dpc-1303	49	30	cases	case	NOUN
dpc-1303	49	31	and	and	CCONJ
dpc-1303	49	32	minimal	minimal	ADJ
dpc-1303	49	33	or	or	CCONJ
dpc-1303	49	34	no	no	DET
dpc-1303	49	35	therapy	therapy	NOUN
dpc-1303	49	36	for	for	ADP
dpc-1303	49	37	patients	patient	NOUN
dpc-1303	49	38	with	with	ADP
dpc-1303	49	39	pv	pv	NOUN
dpc-1303	49	40	in	in	ADP
dpc-1303	49	41	remission	remission	NOUN
dpc-1303	49	42	(	(	PUNCT
dpc-1303	49	43	based	base	VERB
dpc-1303	49	44	on	on	ADP
dpc-1303	49	45	the	the	DET
dpc-1303	49	46	2008	2008	NUM
dpc-1303	49	47	consensus	consensus	NOUN
dpc-1303	49	48	statement	statement	NOUN
dpc-1303	49	49	on	on	ADP
dpc-1303	49	50	definitions	definition	NOUN
dpc-1303	49	51	of	of	ADP
dpc-1303	49	52	pemphigus	pemphigus	NOUN
dpc-1303	49	53	)	)	PUNCT
dpc-1303	50	1	[	[	X
dpc-1303	50	2	16	16	NUM
dpc-1303	50	3	]	]	PUNCT
dpc-1303	50	4	,	,	PUNCT
dpc-1303	50	5	and	and	CCONJ
dpc-1303	50	6	(	(	PUNCT
dpc-1303	50	7	3	3	X
dpc-1303	50	8	)	)	PUNCT
dpc-1303	50	9	absence	absence	NOUN
dpc-1303	50	10	of	of	ADP
dpc-1303	50	11	biological	biological	ADJ
dpc-1303	50	12	therapies	therapy	NOUN
dpc-1303	50	13	in	in	ADP
dpc-1303	50	14	the	the	DET
dpc-1303	50	15	past	past	ADJ
dpc-1303	50	16	6	6	NUM
dpc-1303	50	17	months	month	NOUN
dpc-1303	50	18	.	.	PUNCT
dpc-1303	51	1	patients	patient	NOUN
dpc-1303	51	2	in	in	ADP
dpc-1303	51	3	the	the	DET
dpc-1303	51	4	pv	pv	NOUN
dpc-1303	51	5	in	in	ADP
dpc-1303	51	6	remission	remission	NOUN
dpc-1303	51	7	group	group	NOUN
dpc-1303	51	8	were	be	AUX
dpc-1303	51	9	either	either	CCONJ
dpc-1303	51	10	in	in	ADP
dpc-1303	51	11	complete	complete	ADJ
dpc-1303	51	12	remission	remission	NOUN
dpc-1303	51	13	,	,	PUNCT
dpc-1303	51	14	defined	define	VERB
dpc-1303	51	15	as	as	ADP
dpc-1303	51	16	having	have	VERB
dpc-1303	51	17	no	no	DET
dpc-1303	51	18	new	new	ADJ
dpc-1303	51	19	kine	kine	NOUN
dpc-1303	51	20	levels	level	NOUN
dpc-1303	51	21	in	in	ADP
dpc-1303	51	22	patients	patient	NOUN
dpc-1303	51	23	with	with	ADP
dpc-1303	51	24	pv	pv	NOUN
dpc-1303	51	25	in	in	ADP
dpc-1303	51	26	remission	remission	NOUN
dpc-1303	51	27	were	be	AUX
dpc-1303	51	28	not	not	PART
dpc-1303	51	29	different	different	ADJ
dpc-1303	51	30	from	from	ADP
dpc-1303	51	31	those	those	PRON
dpc-1303	51	32	of	of	ADP
dpc-1303	51	33	controls	control	NOUN
dpc-1303	51	34	(	(	PUNCT
dpc-1303	51	35	p	p	NOUN
dpc-1303	51	36	=	=	PUNCT
dpc-1303	51	37	.343	.343	NUM
dpc-1303	51	38	and	and	CCONJ
dpc-1303	51	39	p	p	X
dpc-1303	51	40	 	 	SPACE
dpc-1303	51	41	=	=	NOUN
dpc-1303	51	42	.221	.221	NUM
dpc-1303	51	43	,	,	PUNCT
dpc-1303	51	44	respectively	respectively	ADV
dpc-1303	51	45	)	)	PUNCT
dpc-1303	51	46	.	.	PUNCT
dpc-1303	52	1	also	also	ADV
dpc-1303	52	2	,	,	PUNCT
dpc-1303	52	3	no	no	DET
dpc-1303	52	4	differences	difference	NOUN
dpc-1303	52	5	in	in	ADP
dpc-1303	52	6	cytokine	cytokine	ADJ
dpc-1303	52	7	levels	level	NOUN
dpc-1303	52	8	were	be	AUX
dpc-1303	52	9	detected	detect	VERB
dpc-1303	52	10	between	between	ADP
dpc-1303	52	11	the	the	DET
dpc-1303	52	12	newly	newly	ADV
dpc-1303	52	13	diagnosed	diagnose	VERB
dpc-1303	52	14	patients	patient	NOUN
dpc-1303	52	15	and	and	CCONJ
dpc-1303	52	16	patients	patient	NOUN
dpc-1303	52	17	with	with	ADP
dpc-1303	52	18	pv	pv	NOUN
dpc-1303	52	19	in	in	ADP
dpc-1303	52	20	remission	remission	NOUN
dpc-1303	52	21	.	.	PUNCT
dpc-1303	53	1	regardless	regardless	ADV
dpc-1303	53	2	of	of	ADP
dpc-1303	53	3	disease	disease	NOUN
dpc-1303	53	4	phase	phase	NOUN
dpc-1303	53	5	,	,	PUNCT
dpc-1303	53	6	we	we	PRON
dpc-1303	53	7	detected	detect	VERB
dpc-1303	53	8	significantly	significantly	ADV
dpc-1303	53	9	lower	low	ADJ
dpc-1303	53	10	levels	level	NOUN
dpc-1303	53	11	of	of	ADP
dpc-1303	53	12	il-21	il-21	NOUN
dpc-1303	53	13	in	in	ADP
dpc-1303	53	14	patients	patient	NOUN
dpc-1303	53	15	than	than	ADP
dpc-1303	53	16	controls	control	NOUN
dpc-1303	53	17	(	(	PUNCT
dpc-1303	53	18	p	p	X
dpc-1303	53	19	=	=	NOUN
dpc-1303	53	20	.027	.027	NUM
dpc-1303	53	21	)	)	PUNCT
dpc-1303	53	22	,	,	PUNCT
dpc-1303	53	23	but	but	CCONJ
dpc-1303	53	24	no	no	DET
dpc-1303	53	25	differences	difference	NOUN
dpc-1303	53	26	for	for	ADP
dpc-1303	53	27	il-4	il-4	NOUN
dpc-1303	53	28	(	(	PUNCT
dpc-1303	53	29	p	p	X
dpc-1303	53	30	=	=	NOUN
dpc-1303	53	31	.374	.374	NUM
dpc-1303	53	32	)	)	PUNCT
dpc-1303	53	33	.	.	PUNCT
dpc-1303	54	1	conclusions	conclusion	NOUN
dpc-1303	54	2	:	:	PUNCT
dpc-1303	54	3	il-4	il-4	NOUN
dpc-1303	55	1	and	and	CCONJ
dpc-1303	55	2	il-21	il-21	NOUN
dpc-1303	55	3	are	be	AUX
dpc-1303	55	4	involved	involve	VERB
dpc-1303	55	5	in	in	ADP
dpc-1303	55	6	pv	pv	NOUN
dpc-1303	55	7	pathogenesis	pathogenesis	NOUN
dpc-1303	55	8	and	and	CCONJ
dpc-1303	55	9	disease	disease	NOUN
dpc-1303	55	10	severity	severity	NOUN
dpc-1303	55	11	.	.	PUNCT
dpc-1303	56	1	more	more	ADJ
dpc-1303	56	2	studies	study	NOUN
dpc-1303	56	3	are	be	AUX
dpc-1303	56	4	required	require	VERB
dpc-1303	56	5	to	to	PART
dpc-1303	56	6	clarify	clarify	VERB
dpc-1303	56	7	the	the	DET
dpc-1303	56	8	role	role	NOUN
dpc-1303	56	9	of	of	ADP
dpc-1303	56	10	il-4	il-4	NOUN
dpc-1303	56	11	and	and	CCONJ
dpc-1303	56	12	il-21	il-21	X
dpc-1303	56	13	in	in	ADP
dpc-1303	56	14	immunopathogenesis	immunopathogenesis	NOUN
dpc-1303	56	15	and	and	CCONJ
dpc-1303	56	16	immune	immune	ADJ
dpc-1303	56	17	response	response	NOUN
dpc-1303	56	18	during	during	ADP
dpc-1303	56	19	pv	pv	PROPN
dpc-1303	56	20	.	.	PUNCT
dpc-1303	57	1	research	research	NOUN
dpc-1303	57	2	|	|	ADV
dpc-1303	57	3	dermatol	dermatol	ADJ
dpc-1303	57	4	pract	pract	NOUN
dpc-1303	57	5	concept	concept	NOUN
dpc-1303	57	6	2021;11(2):e2021035	2021;11(2):e2021035	NUM
dpc-1303	57	7	3	3	NUM
dpc-1303	57	8	or	or	CCONJ
dpc-1303	57	9	established	establish	VERB
dpc-1303	57	10	lesions	lesion	NOUN
dpc-1303	57	11	for	for	ADP
dpc-1303	57	12	at	at	ADV
dpc-1303	57	13	least	least	ADV
dpc-1303	57	14	2	2	NUM
dpc-1303	57	15	months	month	NOUN
dpc-1303	57	16	,	,	PUNCT
dpc-1303	57	17	or	or	CCONJ
dpc-1303	57	18	partial	partial	ADJ
dpc-1303	57	19	remission	remission	NOUN
dpc-1303	57	20	,	,	PUNCT
dpc-1303	57	21	defined	define	VERB
dpc-1303	57	22	as	as	ADP
dpc-1303	57	23	the	the	DET
dpc-1303	57	24	presence	presence	NOUN
dpc-1303	57	25	of	of	ADP
dpc-1303	57	26	transient	transient	ADJ
dpc-1303	57	27	new	new	ADJ
dpc-1303	57	28	lesions	lesion	NOUN
dpc-1303	57	29	that	that	PRON
dpc-1303	57	30	heal	heal	VERB
dpc-1303	57	31	within	within	ADP
dpc-1303	57	32	1	1	NUM
dpc-1303	57	33	week	week	NOUN
dpc-1303	57	34	without	without	ADP
dpc-1303	57	35	treatment	treatment	NOUN
dpc-1303	57	36	.	.	PUNCT
dpc-1303	58	1	those	those	PRON
dpc-1303	58	2	in	in	ADP
dpc-1303	58	3	the	the	DET
dpc-1303	58	4	control	control	NOUN
dpc-1303	58	5	group	group	NOUN
dpc-1303	58	6	were	be	AUX
dpc-1303	58	7	completely	completely	ADV
dpc-1303	58	8	healthy	healthy	ADJ
dpc-1303	58	9	and	and	CCONJ
dpc-1303	58	10	had	have	VERB
dpc-1303	58	11	no	no	DET
dpc-1303	58	12	history	history	NOUN
dpc-1303	58	13	of	of	ADP
dpc-1303	58	14	any	any	DET
dpc-1303	58	15	skin	skin	NOUN
dpc-1303	58	16	disease	disease	NOUN
dpc-1303	58	17	,	,	PUNCT
dpc-1303	58	18	autoimmune	autoimmune	ADJ
dpc-1303	58	19	disease	disease	NOUN
dpc-1303	58	20	,	,	PUNCT
dpc-1303	58	21	or	or	CCONJ
dpc-1303	58	22	malignancy	malignancy	NOUN
dpc-1303	58	23	.	.	PUNCT
dpc-1303	59	1	patients	patient	NOUN
dpc-1303	59	2	in	in	ADP
dpc-1303	59	3	remission	remission	NOUN
dpc-1303	59	4	who	who	PRON
dpc-1303	59	5	developed	develop	VERB
dpc-1303	59	6	a	a	DET
dpc-1303	59	7	new	new	ADJ
dpc-1303	59	8	lesion	lesion	NOUN
dpc-1303	59	9	within	within	ADP
dpc-1303	59	10	the	the	DET
dpc-1303	59	11	past	past	ADJ
dpc-1303	59	12	2	2	NUM
dpc-1303	59	13	months	month	NOUN
dpc-1303	59	14	or	or	CCONJ
dpc-1303	59	15	who	who	PRON
dpc-1303	59	16	had	have	VERB
dpc-1303	59	17	old	old	ADJ
dpc-1303	59	18	,	,	PUNCT
dpc-1303	59	19	persistent	persistent	ADJ
dpc-1303	59	20	lesion(s	lesion(s	NOUN
dpc-1303	59	21	)	)	PUNCT
dpc-1303	59	22	were	be	AUX
dpc-1303	59	23	excluded	exclude	VERB
dpc-1303	59	24	.	.	PUNCT
dpc-1303	60	1	also	also	ADV
dpc-1303	60	2	excluded	exclude	VERB
dpc-1303	60	3	were	be	AUX
dpc-1303	60	4	pregnant	pregnant	ADJ
dpc-1303	60	5	women	woman	NOUN
dpc-1303	60	6	,	,	PUNCT
dpc-1303	60	7	patients	patient	NOUN
dpc-1303	60	8	with	with	ADP
dpc-1303	60	9	other	other	ADJ
dpc-1303	60	10	subtypes	subtype	NOUN
dpc-1303	60	11	of	of	ADP
dpc-1303	60	12	pemphigus	pemphigus	NOUN
dpc-1303	60	13	,	,	PUNCT
dpc-1303	60	14	and	and	CCONJ
dpc-1303	60	15	,	,	PUNCT
dpc-1303	60	16	during	during	ADP
dpc-1303	60	17	the	the	DET
dpc-1303	60	18	study	study	NOUN
dpc-1303	60	19	,	,	PUNCT
dpc-1303	60	20	any	any	DET
dpc-1303	60	21	patient	patient	NOUN
dpc-1303	60	22	in	in	ADP
dpc-1303	60	23	the	the	DET
dpc-1303	60	24	pv	pv	NOUN
dpc-1303	60	25	in	in	ADP
dpc-1303	60	26	remission	remission	NOUN
dpc-1303	60	27	group	group	NOUN
dpc-1303	60	28	whose	whose	DET
dpc-1303	60	29	disease	disease	NOUN
dpc-1303	60	30	became	become	VERB
dpc-1303	60	31	active	active	ADJ
dpc-1303	60	32	,	,	PUNCT
dpc-1303	60	33	defined	define	VERB
dpc-1303	60	34	as	as	ADP
dpc-1303	60	35	the	the	DET
dpc-1303	60	36	development	development	NOUN
dpc-1303	60	37	of	of	ADP
dpc-1303	60	38	new	new	ADJ
dpc-1303	60	39	lesions	lesion	NOUN
dpc-1303	60	40	that	that	PRON
dpc-1303	60	41	did	do	AUX
dpc-1303	60	42	not	not	PART
dpc-1303	60	43	heal	heal	VERB
dpc-1303	60	44	within	within	ADP
dpc-1303	60	45	1	1	NUM
dpc-1303	60	46	week	week	NOUN
dpc-1303	60	47	without	without	ADP
dpc-1303	60	48	additional	additional	ADJ
dpc-1303	60	49	treatment	treatment	NOUN
dpc-1303	60	50	.	.	PUNCT
dpc-1303	61	1	all	all	DET
dpc-1303	61	2	study	study	NOUN
dpc-1303	61	3	subjects	subject	NOUN
dpc-1303	61	4	provided	provide	VERB
dpc-1303	61	5	written	write	VERB
dpc-1303	61	6	informed	inform	VERB
dpc-1303	61	7	consent	consent	NOUN
dpc-1303	61	8	.	.	PUNCT
dpc-1303	62	1	after	after	ADP
dpc-1303	62	2	signing	sign	VERB
dpc-1303	62	3	the	the	DET
dpc-1303	62	4	consent	consent	NOUN
dpc-1303	62	5	letter	letter	NOUN
dpc-1303	62	6	,	,	PUNCT
dpc-1303	62	7	6	6	NUM
dpc-1303	62	8	ml	ml	NOUN
dpc-1303	62	9	of	of	ADP
dpc-1303	62	10	whole	whole	ADJ
dpc-1303	62	11	blood	blood	NOUN
dpc-1303	62	12	was	be	AUX
dpc-1303	62	13	taken	take	VERB
dpc-1303	62	14	from	from	ADP
dpc-1303	62	15	each	each	DET
dpc-1303	62	16	contributor	contributor	NOUN
dpc-1303	62	17	.	.	PUNCT
dpc-1303	63	1	serum	serum	PROPN
dpc-1303	63	2	was	be	AUX
dpc-1303	63	3	separated	separate	VERB
dpc-1303	63	4	and	and	CCONJ
dpc-1303	63	5	then	then	ADV
dpc-1303	63	6	stored	store	VERB
dpc-1303	63	7	in	in	ADP
dpc-1303	63	8	-70	-70	PROPN
dpc-1303	63	9	°	°	ADP
dpc-1303	63	10	c	c	NOUN
dpc-1303	63	11	for	for	ADP
dpc-1303	63	12	further	further	ADJ
dpc-1303	63	13	experiments	experiment	NOUN
dpc-1303	63	14	.	.	PUNCT
dpc-1303	64	1	serum	serum	NOUN
dpc-1303	64	2	levels	level	NOUN
dpc-1303	64	3	of	of	ADP
dpc-1303	64	4	il-4	il-4	NOUN
dpc-1303	64	5	and	and	CCONJ
dpc-1303	64	6	il-21	il-21	NOUN
dpc-1303	64	7	were	be	AUX
dpc-1303	64	8	measured	measure	VERB
dpc-1303	64	9	using	use	VERB
dpc-1303	64	10	elisa	elisa	PROPN
dpc-1303	64	11	kits	kit	NOUN
dpc-1303	64	12	(	(	PUNCT
dpc-1303	64	13	thermo	thermo	NOUN
dpc-1303	64	14	fisher	fisher	PROPN
dpc-1303	64	15	scientific	scientific	PROPN
dpc-1303	64	16	)	)	PUNCT
dpc-1303	64	17	.	.	PUNCT
dpc-1303	65	1	study	study	NOUN
dpc-1303	65	2	evaluation	evaluation	NOUN
dpc-1303	65	3	and	and	CCONJ
dpc-1303	65	4	statistical	statistical	ADJ
dpc-1303	65	5	analysis	analysis	NOUN
dpc-1303	65	6	demographic	demographic	ADJ
dpc-1303	65	7	data	datum	NOUN
dpc-1303	65	8	,	,	PUNCT
dpc-1303	65	9	history	history	NOUN
dpc-1303	65	10	of	of	ADP
dpc-1303	65	11	the	the	DET
dpc-1303	65	12	disease	disease	NOUN
dpc-1303	65	13	,	,	PUNCT
dpc-1303	65	14	and	and	CCONJ
dpc-1303	65	15	type	type	NOUN
dpc-1303	65	16	of	of	ADP
dpc-1303	65	17	therapy	therapy	NOUN
dpc-1303	65	18	used	use	VERB
dpc-1303	65	19	were	be	AUX
dpc-1303	65	20	recorded	record	VERB
dpc-1303	65	21	and	and	CCONJ
dpc-1303	65	22	collected	collect	VERB
dpc-1303	65	23	for	for	ADP
dpc-1303	65	24	each	each	DET
dpc-1303	65	25	patient	patient	NOUN
dpc-1303	65	26	.	.	PUNCT
dpc-1303	66	1	results	result	NOUN
dpc-1303	66	2	for	for	ADP
dpc-1303	66	3	serum	serum	NOUN
dpc-1303	66	4	concentrations	concentration	NOUN
dpc-1303	66	5	of	of	ADP
dpc-1303	66	6	cytokines	cytokine	NOUN
dpc-1303	66	7	are	be	AUX
dpc-1303	66	8	presented	present	VERB
dpc-1303	66	9	as	as	ADP
dpc-1303	66	10	a	a	DET
dpc-1303	66	11	mean	mean	ADJ
dpc-1303	66	12	±	±	NOUN
dpc-1303	66	13	standard	standard	ADJ
dpc-1303	66	14	deviation	deviation	NOUN
dpc-1303	66	15	and	and	CCONJ
dpc-1303	66	16	median	median	NOUN
dpc-1303	66	17	.	.	PUNCT
dpc-1303	67	1	to	to	PART
dpc-1303	67	2	compare	compare	VERB
dpc-1303	67	3	the	the	DET
dpc-1303	67	4	mean	mean	ADJ
dpc-1303	67	5	concentrations	concentration	NOUN
dpc-1303	67	6	in	in	ADP
dpc-1303	67	7	the	the	DET
dpc-1303	67	8	groups	group	NOUN
dpc-1303	67	9	of	of	ADP
dpc-1303	67	10	patients	patient	NOUN
dpc-1303	67	11	,	,	PUNCT
dpc-1303	67	12	an	an	DET
dpc-1303	67	13	independent	independent	ADJ
dpc-1303	67	14	t	t	NOUN
dpc-1303	67	15	test	test	NOUN
dpc-1303	67	16	was	be	AUX
dpc-1303	67	17	used	use	VERB
dpc-1303	67	18	.	.	PUNCT
dpc-1303	68	1	to	to	PART
dpc-1303	68	2	compare	compare	VERB
dpc-1303	68	3	more	more	ADJ
dpc-1303	68	4	than	than	ADP
dpc-1303	68	5	2	2	NUM
dpc-1303	68	6	samples	sample	NOUN
dpc-1303	68	7	separately	separately	ADV
dpc-1303	68	8	,	,	PUNCT
dpc-1303	68	9	a	a	DET
dpc-1303	68	10	one	one	NUM
dpc-1303	68	11	-	-	PUNCT
dpc-1303	68	12	way	way	NOUN
dpc-1303	68	13	anova	anova	PROPN
dpc-1303	68	14	test	test	NOUN
dpc-1303	68	15	was	be	AUX
dpc-1303	68	16	used	use	VERB
dpc-1303	68	17	.	.	PUNCT
dpc-1303	69	1	statistical	statistical	ADJ
dpc-1303	69	2	analyses	analysis	NOUN
dpc-1303	69	3	were	be	AUX
dpc-1303	69	4	performed	perform	VERB
dpc-1303	69	5	using	use	VERB
dpc-1303	69	6	spss	spss	PROPN
dpc-1303	69	7	v.20.0	v.20.0	PROPN
dpc-1303	69	8	(	(	PUNCT
dpc-1303	69	9	ibm	ibm	PROPN
dpc-1303	69	10	corp	corp	PROPN
dpc-1303	69	11	.	.	PROPN
dpc-1303	69	12	,	,	PUNCT
dpc-1303	69	13	armonk	armonk	PROPN
dpc-1303	69	14	,	,	PUNCT
dpc-1303	69	15	ny	ny	PROPN
dpc-1303	69	16	,	,	PUNCT
dpc-1303	69	17	usa	usa	PROPN
dpc-1303	69	18	)	)	PUNCT
dpc-1303	69	19	.	.	PUNCT
dpc-1303	70	1	p	p	NOUN
dpc-1303	70	2	values	value	NOUN
dpc-1303	70	3	<	<	X
dpc-1303	70	4	.05	.05	NUM
dpc-1303	70	5	were	be	AUX
dpc-1303	70	6	considered	consider	VERB
dpc-1303	70	7	significant	significant	ADJ
dpc-1303	70	8	.	.	PUNCT
dpc-1303	71	1	data	datum	NOUN
dpc-1303	71	2	were	be	AUX
dpc-1303	71	3	graphed	graph	VERB
dpc-1303	71	4	using	use	VERB
dpc-1303	71	5	the	the	DET
dpc-1303	71	6	graphpad	graphpad	NOUN
dpc-1303	71	7	prism	prism	NOUN
dpc-1303	71	8	program	program	NOUN
dpc-1303	71	9	(	(	PUNCT
dpc-1303	71	10	version	version	NOUN
dpc-1303	71	11	7.00	7.00	NUM
dpc-1303	71	12	,	,	PUNCT
dpc-1303	71	13	graphpad	graphpad	PROPN
dpc-1303	71	14	software	software	PROPN
dpc-1303	71	15	inc	inc	PROPN
dpc-1303	71	16	.	.	PROPN
dpc-1303	71	17	)	)	PUNCT
dpc-1303	71	18	.	.	PUNCT
dpc-1303	72	1	ethical	ethical	ADJ
dpc-1303	72	2	considerations	consideration	NOUN
dpc-1303	72	3	the	the	DET
dpc-1303	72	4	study	study	NOUN
dpc-1303	72	5	was	be	AUX
dpc-1303	72	6	approved	approve	VERB
dpc-1303	72	7	by	by	ADP
dpc-1303	72	8	the	the	DET
dpc-1303	72	9	ethics	ethic	NOUN
dpc-1303	72	10	committee	committee	PROPN
dpc-1303	72	11	of	of	ADP
dpc-1303	72	12	tehran	tehran	PROPN
dpc-1303	72	13	university	university	PROPN
dpc-1303	72	14	of	of	ADP
dpc-1303	72	15	medical	medical	ADJ
dpc-1303	72	16	sciences	science	NOUN
dpc-1303	72	17	before	before	ADP
dpc-1303	72	18	initiating	initiate	VERB
dpc-1303	72	19	,	,	PUNCT
dpc-1303	72	20	and	and	CCONJ
dpc-1303	72	21	all	all	DET
dpc-1303	72	22	persons	person	NOUN
dpc-1303	72	23	who	who	PRON
dpc-1303	72	24	were	be	AUX
dpc-1303	72	25	enrolled	enrol	VERB
dpc-1303	72	26	provided	provide	VERB
dpc-1303	72	27	written	write	VERB
dpc-1303	72	28	informed	inform	VERB
dpc-1303	72	29	consent	consent	NOUN
dpc-1303	72	30	.	.	PUNCT
dpc-1303	73	1	the	the	DET
dpc-1303	73	2	study	study	NOUN
dpc-1303	73	3	was	be	AUX
dpc-1303	73	4	conducted	conduct	VERB
dpc-1303	73	5	in	in	ADP
dpc-1303	73	6	accordance	accordance	NOUN
dpc-1303	73	7	with	with	ADP
dpc-1303	73	8	the	the	DET
dpc-1303	73	9	declaration	declaration	NOUN
dpc-1303	73	10	of	of	ADP
dpc-1303	73	11	helsinki	helsinki	PROPN
dpc-1303	73	12	.	.	PUNCT
dpc-1303	74	1	patients	patient	NOUN
dpc-1303	74	2	’	'	PUNCT
dpc-1303	74	3	information	information	NOUN
dpc-1303	74	4	was	be	AUX
dpc-1303	74	5	kept	keep	VERB
dpc-1303	74	6	confidential	confidential	ADJ
dpc-1303	74	7	and	and	CCONJ
dpc-1303	74	8	no	no	DET
dpc-1303	74	9	patient	patient	NOUN
dpc-1303	74	10	/	/	SYM
dpc-1303	74	11	individual	individual	NOUN
dpc-1303	74	12	paid	pay	VERB
dpc-1303	74	13	any	any	DET
dpc-1303	74	14	charges	charge	NOUN
dpc-1303	74	15	.	.	PUNCT
dpc-1303	75	1	results	result	VERB
dpc-1303	75	2	a	a	DET
dpc-1303	75	3	total	total	NOUN
dpc-1303	75	4	of	of	ADP
dpc-1303	75	5	88	88	NUM
dpc-1303	75	6	patients	patient	NOUN
dpc-1303	75	7	was	be	AUX
dpc-1303	75	8	enrolled	enrol	VERB
dpc-1303	75	9	,	,	PUNCT
dpc-1303	75	10	including	include	VERB
dpc-1303	75	11	26	26	NUM
dpc-1303	75	12	(	(	PUNCT
dpc-1303	75	13	29.5	29.5	NUM
dpc-1303	75	14	%	%	NOUN
dpc-1303	75	15	)	)	PUNCT
dpc-1303	75	16	newly	newly	ADV
dpc-1303	75	17	diagnosed	diagnose	VERB
dpc-1303	75	18	pv	pv	NOUN
dpc-1303	75	19	patients	patient	NOUN
dpc-1303	75	20	,	,	PUNCT
dpc-1303	75	21	33	33	NUM
dpc-1303	75	22	(	(	PUNCT
dpc-1303	75	23	37.5	37.5	NUM
dpc-1303	75	24	%	%	NOUN
dpc-1303	75	25	)	)	PUNCT
dpc-1303	75	26	patients	patient	NOUN
dpc-1303	75	27	with	with	ADP
dpc-1303	75	28	pv	pv	NOUN
dpc-1303	75	29	in	in	ADP
dpc-1303	75	30	remission	remission	NOUN
dpc-1303	75	31	,	,	PUNCT
dpc-1303	75	32	and	and	CCONJ
dpc-1303	75	33	29	29	NUM
dpc-1303	75	34	(	(	PUNCT
dpc-1303	75	35	33	33	NUM
dpc-1303	75	36	%	%	NOUN
dpc-1303	75	37	)	)	PUNCT
dpc-1303	75	38	healthy	healthy	ADJ
dpc-1303	75	39	controls	control	NOUN
dpc-1303	75	40	who	who	PRON
dpc-1303	75	41	were	be	AUX
dpc-1303	75	42	ageand	ageand	NOUN
dpc-1303	75	43	sex	sex	NOUN
dpc-1303	75	44	-	-	PUNCT
dpc-1303	75	45	matched	match	VERB
dpc-1303	75	46	to	to	ADP
dpc-1303	75	47	the	the	DET
dpc-1303	75	48	59	59	NUM
dpc-1303	75	49	pv	pv	NOUN
dpc-1303	75	50	patients	patient	NOUN
dpc-1303	75	51	.	.	PUNCT
dpc-1303	76	1	in	in	ADP
dpc-1303	76	2	total	total	NOUN
dpc-1303	76	3	,	,	PUNCT
dpc-1303	76	4	58	58	NUM
dpc-1303	76	5	(	(	PUNCT
dpc-1303	76	6	65.9	65.9	NUM
dpc-1303	76	7	%	%	NOUN
dpc-1303	76	8	)	)	PUNCT
dpc-1303	76	9	were	be	AUX
dpc-1303	76	10	females	female	NOUN
dpc-1303	76	11	and	and	CCONJ
dpc-1303	76	12	30	30	NUM
dpc-1303	76	13	(	(	PUNCT
dpc-1303	76	14	34.1	34.1	NUM
dpc-1303	76	15	%	%	NOUN
dpc-1303	76	16	)	)	PUNCT
dpc-1303	76	17	were	be	AUX
dpc-1303	76	18	males	male	NOUN
dpc-1303	76	19	,	,	PUNCT
dpc-1303	76	20	with	with	ADP
dpc-1303	76	21	a	a	DET
dpc-1303	76	22	mean	mean	ADJ
dpc-1303	76	23	age	age	NOUN
dpc-1303	76	24	of	of	ADP
dpc-1303	76	25	42.2	42.2	NUM
dpc-1303	76	26	±	±	NUM
dpc-1303	76	27	10.5	10.5	NUM
dpc-1303	76	28	years	year	NOUN
dpc-1303	76	29	(	(	PUNCT
dpc-1303	76	30	range	range	NOUN
dpc-1303	76	31	,	,	PUNCT
dpc-1303	76	32	20	20	NUM
dpc-1303	76	33	-	-	SYM
dpc-1303	76	34	81	81	NUM
dpc-1303	76	35	)	)	PUNCT
dpc-1303	76	36	.	.	PUNCT
dpc-1303	77	1	demographic	demographic	ADJ
dpc-1303	77	2	data	datum	NOUN
dpc-1303	77	3	for	for	ADP
dpc-1303	77	4	each	each	DET
dpc-1303	77	5	group	group	NOUN
dpc-1303	77	6	are	be	AUX
dpc-1303	77	7	shown	show	VERB
dpc-1303	77	8	in	in	ADP
dpc-1303	77	9	table	table	NOUN
dpc-1303	77	10	1	1	NUM
dpc-1303	77	11	.	.	PUNCT
dpc-1303	77	12	table	table	NOUN
dpc-1303	77	13	2	2	NUM
dpc-1303	77	14	reports	report	VERB
dpc-1303	77	15	the	the	DET
dpc-1303	77	16	serum	serum	NOUN
dpc-1303	77	17	levels	level	NOUN
dpc-1303	77	18	of	of	ADP
dpc-1303	77	19	il-4	il-4	NOUN
dpc-1303	77	20	and	and	CCONJ
dpc-1303	77	21	il-21	il-21	X
dpc-1303	77	22	in	in	ADP
dpc-1303	77	23	the	the	DET
dpc-1303	77	24	3	3	NUM
dpc-1303	77	25	groups	group	NOUN
dpc-1303	77	26	,	,	PUNCT
dpc-1303	77	27	and	and	CCONJ
dpc-1303	77	28	figure	figure	VERB
dpc-1303	77	29	1	1	NUM
dpc-1303	77	30	graphically	graphically	ADV
dpc-1303	77	31	shows	show	VERB
dpc-1303	77	32	the	the	DET
dpc-1303	77	33	serum	serum	NOUN
dpc-1303	77	34	levels	level	NOUN
dpc-1303	77	35	of	of	ADP
dpc-1303	77	36	(	(	PUNCT
dpc-1303	77	37	a	a	NOUN
dpc-1303	77	38	)	)	PUNCT
dpc-1303	77	39	il-4	il-4	NOUN
dpc-1303	78	1	and	and	CCONJ
dpc-1303	78	2	(	(	PUNCT
dpc-1303	78	3	b	b	X
dpc-1303	78	4	)	)	PUNCT
dpc-1303	78	5	il-21	il-21	PRON
dpc-1303	78	6	.	.	PUNCT
dpc-1303	79	1	regarding	regard	VERB
dpc-1303	79	2	il-4	il-4	NOUN
dpc-1303	79	3	,	,	PUNCT
dpc-1303	79	4	no	no	DET
dpc-1303	79	5	significant	significant	ADJ
dpc-1303	79	6	table	table	NOUN
dpc-1303	79	7	1	1	NUM
dpc-1303	79	8	.	.	PUNCT
dpc-1303	80	1	demographic	demographic	ADJ
dpc-1303	80	2	data	datum	NOUN
dpc-1303	80	3	of	of	ADP
dpc-1303	80	4	the	the	DET
dpc-1303	80	5	included	include	VERB
dpc-1303	80	6	patients	patient	NOUN
dpc-1303	80	7	and	and	CCONJ
dpc-1303	80	8	healthy	healthy	ADJ
dpc-1303	80	9	participants	participant	NOUN
dpc-1303	80	10	newly	newly	ADV
dpc-1303	80	11	diagnosed	diagnose	VERB
dpc-1303	80	12	pv	pv	INTJ
dpc-1303	80	13	pv	pv	INTJ
dpc-1303	80	14	in	in	ADP
dpc-1303	80	15	remission	remission	NOUN
dpc-1303	80	16	healthy	healthy	ADJ
dpc-1303	80	17	controls	control	NOUN
dpc-1303	80	18	total	total	ADJ
dpc-1303	80	19	gender	gender	NOUN
dpc-1303	80	20	male	male	NOUN
dpc-1303	80	21	,	,	PUNCT
dpc-1303	80	22	n	n	PROPN
dpc-1303	80	23	(	(	PUNCT
dpc-1303	80	24	%	%	INTJ
dpc-1303	80	25	)	)	PUNCT
dpc-1303	80	26	13	13	NUM
dpc-1303	80	27	(	(	PUNCT
dpc-1303	80	28	43.3	43.3	NUM
dpc-1303	80	29	)	)	PUNCT
dpc-1303	80	30	9	9	NUM
dpc-1303	80	31	(	(	PUNCT
dpc-1303	80	32	30.0	30.0	NUM
dpc-1303	80	33	)	)	PUNCT
dpc-1303	80	34	8	8	NUM
dpc-1303	80	35	(	(	PUNCT
dpc-1303	80	36	26.7	26.7	NUM
dpc-1303	80	37	)	)	PUNCT
dpc-1303	80	38	30	30	NUM
dpc-1303	80	39	(	(	PUNCT
dpc-1303	80	40	100	100	NUM
dpc-1303	80	41	)	)	PUNCT
dpc-1303	80	42	female	female	NOUN
dpc-1303	80	43	,	,	PUNCT
dpc-1303	80	44	n	n	CCONJ
dpc-1303	80	45	(	(	PUNCT
dpc-1303	80	46	%	%	INTJ
dpc-1303	80	47	)	)	PUNCT
dpc-1303	80	48	13	13	NUM
dpc-1303	80	49	(	(	PUNCT
dpc-1303	80	50	22.4	22.4	NUM
dpc-1303	80	51	)	)	SYM
dpc-1303	80	52	24	24	NUM
dpc-1303	80	53	(	(	PUNCT
dpc-1303	80	54	41.4	41.4	NUM
dpc-1303	80	55	)	)	PUNCT
dpc-1303	80	56	21	21	NUM
dpc-1303	80	57	(	(	PUNCT
dpc-1303	80	58	36.2	36.2	NUM
dpc-1303	80	59	)	)	PUNCT
dpc-1303	80	60	58	58	NUM
dpc-1303	80	61	(	(	PUNCT
dpc-1303	80	62	100	100	NUM
dpc-1303	80	63	)	)	PUNCT
dpc-1303	80	64	age	age	NOUN
dpc-1303	80	65	,	,	PUNCT
dpc-1303	80	66	mean	mean	VERB
dpc-1303	80	67	±	±	NUM
dpc-1303	80	68	sd	sd	NOUN
dpc-1303	80	69	(	(	PUNCT
dpc-1303	80	70	range	range	NOUN
dpc-1303	80	71	)	)	PUNCT
dpc-1303	80	72	,	,	PUNCT
dpc-1303	80	73	y	y	PROPN
dpc-1303	80	74	44.6	44.6	NUM
dpc-1303	80	75	±	±	NUM
dpc-1303	80	76	9.0	9.0	NUM
dpc-1303	80	77	(	(	PUNCT
dpc-1303	80	78	32	32	NUM
dpc-1303	80	79	-	-	SYM
dpc-1303	80	80	70	70	NUM
dpc-1303	80	81	)	)	PUNCT
dpc-1303	80	82	43.6	43.6	NUM
dpc-1303	80	83	±	±	NUM
dpc-1303	80	84	9.2	9.2	NUM
dpc-1303	80	85	(	(	PUNCT
dpc-1303	80	86	28	28	NUM
dpc-1303	80	87	-	-	SYM
dpc-1303	80	88	59	59	NUM
dpc-1303	80	89	)	)	PUNCT
dpc-1303	80	90	38.5	38.5	NUM
dpc-1303	80	91	±	±	NUM
dpc-1303	80	92	12.4	12.4	NUM
dpc-1303	80	93	(	(	PUNCT
dpc-1303	80	94	20	20	NUM
dpc-1303	80	95	-	-	SYM
dpc-1303	80	96	81	81	NUM
dpc-1303	80	97	)	)	PUNCT
dpc-1303	80	98	42.2	42.2	NUM
dpc-1303	80	99	±	±	NUM
dpc-1303	80	100	10.5	10.5	NUM
dpc-1303	80	101	(	(	PUNCT
dpc-1303	80	102	20	20	NUM
dpc-1303	80	103	-	-	SYM
dpc-1303	80	104	81	81	NUM
dpc-1303	80	105	)	)	PUNCT
dpc-1303	80	106	pv	pv	NOUN
dpc-1303	80	107	=	=	PUNCT
dpc-1303	80	108	pemphigus	pemphigus	NOUN
dpc-1303	80	109	vulgaris	vulgaris	NOUN
dpc-1303	80	110	.	.	PUNCT
dpc-1303	80	111	table	table	NOUN
dpc-1303	81	1	2	2	NUM
dpc-1303	81	2	.	.	PUNCT
dpc-1303	81	3	il-4	il-4	NOUN
dpc-1303	82	1	and	and	CCONJ
dpc-1303	82	2	il-21	il-21	NOUN
dpc-1303	82	3	levels	level	NOUN
dpc-1303	82	4	(	(	PUNCT
dpc-1303	82	5	pg	pg	NOUN
dpc-1303	82	6	/	/	SYM
dpc-1303	82	7	ml	ml	VERB
dpc-1303	82	8	)	)	PUNCT
dpc-1303	82	9	in	in	ADP
dpc-1303	82	10	different	different	ADJ
dpc-1303	82	11	phases	phase	NOUN
dpc-1303	82	12	of	of	ADP
dpc-1303	82	13	the	the	DET
dpc-1303	82	14	disease	disease	NOUN
dpc-1303	82	15	group	group	NOUN
dpc-1303	82	16	no	no	INTJ
dpc-1303	82	17	.	.	PUNCT
dpc-1303	83	1	mean	mean	PROPN
dpc-1303	83	2	±	±	PROPN
dpc-1303	83	3	sd	sd	ADP
dpc-1303	83	4	median	median	ADJ
dpc-1303	83	5	range	range	NOUN
dpc-1303	83	6	p	p	NOUN
dpc-1303	83	7	il-4	il-4	ADV
dpc-1303	83	8	newly	newly	ADV
dpc-1303	83	9	diagnosed	diagnose	VERB
dpc-1303	84	1	pv	pv	NOUN
dpc-1303	84	2	26	26	NUM
dpc-1303	84	3	8.63	8.63	NUM
dpc-1303	84	4	±	±	NUM
dpc-1303	84	5	2.58	2.58	NUM
dpc-1303	84	6	9.06	9.06	NUM
dpc-1303	84	7	1.88	1.88	NUM
dpc-1303	84	8	-	-	SYM
dpc-1303	84	9	13.75	13.75	NUM
dpc-1303	84	10	.374	.374	NUM
dpc-1303	84	11	pv	pv	NOUN
dpc-1303	84	12	in	in	ADP
dpc-1303	84	13	remission	remission	NOUN
dpc-1303	84	14	33	33	NUM
dpc-1303	84	15	15.92	15.92	NUM
dpc-1303	84	16	±	±	NUM
dpc-1303	84	17	38.75	38.75	NUM
dpc-1303	84	18	8.75	8.75	NUM
dpc-1303	84	19	5.0	5.0	NUM
dpc-1303	84	20	-	-	SYM
dpc-1303	84	21	231.2	231.2	NUM
dpc-1303	84	22	total	total	NOUN
dpc-1303	84	23	59	59	NUM
dpc-1303	84	24	12.71	12.71	NUM
dpc-1303	84	25	±	±	NUM
dpc-1303	84	26	29.06	29.06	NUM
dpc-1303	84	27	8.75	8.75	NUM
dpc-1303	84	28	1.88	1.88	NUM
dpc-1303	84	29	-	-	SYM
dpc-1303	84	30	231.2	231.2	NUM
dpc-1303	84	31	healthy	healthy	ADJ
dpc-1303	84	32	controls	control	NOUN
dpc-1303	84	33	29	29	NUM
dpc-1303	84	34	17.89	17.89	NUM
dpc-1303	84	35	±	±	NOUN
dpc-1303	84	36	15.99	15.99	NUM
dpc-1303	84	37	12.50	12.50	NUM
dpc-1303	84	38	7.5	7.5	NUM
dpc-1303	84	39	-	-	SYM
dpc-1303	84	40	78.13	78.13	NUM
dpc-1303	84	41	il-21	il-21	NUM
dpc-1303	84	42	newly	newly	ADV
dpc-1303	84	43	diagnosed	diagnose	VERB
dpc-1303	84	44	pv	pv	NOUN
dpc-1303	84	45	26	26	NUM
dpc-1303	84	46	28.21	28.21	NUM
dpc-1303	84	47	±	±	NUM
dpc-1303	84	48	23.81	23.81	NUM
dpc-1303	84	49	21.94	21.94	NUM
dpc-1303	84	50	7.1	7.1	NUM
dpc-1303	84	51	-	-	SYM
dpc-1303	84	52	122.7	122.7	NUM
dpc-1303	84	53	.044	.044	NUM
dpc-1303	84	54	pv	pv	NOUN
dpc-1303	84	55	in	in	ADP
dpc-1303	84	56	remission	remission	NOUN
dpc-1303	84	57	33	33	NUM
dpc-1303	84	58	42.35	42.35	NUM
dpc-1303	84	59	±	±	NUM
dpc-1303	84	60	54.19	54.19	NUM
dpc-1303	84	61	28.03	28.03	NUM
dpc-1303	84	62	10.84	10.84	NUM
dpc-1303	84	63	-	-	SYM
dpc-1303	84	64	269.9	269.9	NUM
dpc-1303	84	65	total	total	NOUN
dpc-1303	84	66	59	59	NUM
dpc-1303	84	67	36.13	36.13	NUM
dpc-1303	84	68	±	±	NOUN
dpc-1303	84	69	43.76	43.76	NUM
dpc-1303	84	70	25.00	25.00	NUM
dpc-1303	84	71	7.1	7.1	NUM
dpc-1303	84	72	-	-	SYM
dpc-1303	84	73	269.9	269.9	NUM
dpc-1303	84	74	healthy	healthy	ADJ
dpc-1303	84	75	controls	control	NOUN
dpc-1303	84	76	29	29	NUM
dpc-1303	84	77	40.65	40.65	NUM
dpc-1303	84	78	±	±	NUM
dpc-1303	84	79	49.37	49.37	NUM
dpc-1303	84	80	43.97	43.97	NUM
dpc-1303	84	81	13.3	13.3	NUM
dpc-1303	84	82	-	-	SYM
dpc-1303	84	83	269.9	269.9	NUM
dpc-1303	84	84	il	il	PROPN
dpc-1303	84	85	=	=	NOUN
dpc-1303	84	86	interleukin	interleukin	NOUN
dpc-1303	84	87	;	;	PUNCT
dpc-1303	84	88	pv	pv	NOUN
dpc-1303	84	89	=	=	PUNCT
dpc-1303	84	90	pemphigus	pemphigus	NOUN
dpc-1303	84	91	vulgaris	vulgaris	NOUN
dpc-1303	84	92	.	.	PUNCT
dpc-1303	85	1	4	4	NUM
dpc-1303	85	2	research	research	NOUN
dpc-1303	85	3	|	|	ADV
dpc-1303	85	4	dermatol	dermatol	ADJ
dpc-1303	85	5	pract	pract	NOUN
dpc-1303	85	6	concept	concept	NOUN
dpc-1303	85	7	2021;11(2):e2021035	2021;11(2):e2021035	NUM
dpc-1303	85	8	difference	difference	NOUN
dpc-1303	85	9	among	among	ADP
dpc-1303	85	10	the	the	DET
dpc-1303	85	11	groups	group	NOUN
dpc-1303	85	12	was	be	AUX
dpc-1303	85	13	found	find	VERB
dpc-1303	85	14	(	(	PUNCT
dpc-1303	85	15	p	p	X
dpc-1303	85	16	=	=	NOUN
dpc-1303	85	17	.374	.374	NUM
dpc-1303	85	18	,	,	PUNCT
dpc-1303	85	19	anova	anova	PROPN
dpc-1303	85	20	)	)	PUNCT
dpc-1303	85	21	.	.	PUNCT
dpc-1303	86	1	however	however	ADV
dpc-1303	86	2	,	,	PUNCT
dpc-1303	86	3	new	new	ADJ
dpc-1303	86	4	cases	case	NOUN
dpc-1303	86	5	had	have	VERB
dpc-1303	86	6	significantly	significantly	ADV
dpc-1303	86	7	different	different	ADJ
dpc-1303	86	8	serum	serum	NOUN
dpc-1303	86	9	levels	level	NOUN
dpc-1303	86	10	of	of	ADP
dpc-1303	86	11	il-4	il-4	NOUN
dpc-1303	86	12	than	than	ADP
dpc-1303	86	13	healthy	healthy	ADJ
dpc-1303	86	14	controls	control	NOUN
dpc-1303	86	15	(	(	PUNCT
dpc-1303	86	16	p	p	X
dpc-1303	86	17	=	=	NOUN
dpc-1303	86	18	.005	.005	NUM
dpc-1303	86	19	)	)	PUNCT
dpc-1303	86	20	.	.	PUNCT
dpc-1303	87	1	indeed	indeed	ADV
dpc-1303	87	2	,	,	PUNCT
dpc-1303	87	3	new	new	ADJ
dpc-1303	87	4	patients	patient	NOUN
dpc-1303	87	5	with	with	ADP
dpc-1303	87	6	active	active	ADJ
dpc-1303	87	7	disease	disease	NOUN
dpc-1303	87	8	had	have	VERB
dpc-1303	87	9	lower	low	ADJ
dpc-1303	87	10	mean	mean	ADJ
dpc-1303	87	11	levels	level	NOUN
dpc-1303	87	12	of	of	ADP
dpc-1303	87	13	il-4	il-4	NOUN
dpc-1303	87	14	than	than	ADP
dpc-1303	87	15	healthy	healthy	ADJ
dpc-1303	87	16	individuals	individual	NOUN
dpc-1303	87	17	.	.	PUNCT
dpc-1303	88	1	in	in	ADP
dpc-1303	88	2	contrast	contrast	NOUN
dpc-1303	88	3	,	,	PUNCT
dpc-1303	88	4	the	the	DET
dpc-1303	88	5	mean	mean	NOUN
dpc-1303	88	6	of	of	ADP
dpc-1303	88	7	il-4	il-4	NOUN
dpc-1303	88	8	in	in	ADP
dpc-1303	88	9	patients	patient	NOUN
dpc-1303	88	10	with	with	ADP
dpc-1303	88	11	pv	pv	NOUN
dpc-1303	88	12	in	in	ADP
dpc-1303	88	13	remission	remission	NOUN
dpc-1303	88	14	was	be	AUX
dpc-1303	88	15	comparable	comparable	ADJ
dpc-1303	88	16	to	to	ADP
dpc-1303	88	17	that	that	PRON
dpc-1303	88	18	of	of	ADP
dpc-1303	88	19	the	the	DET
dpc-1303	88	20	control	control	NOUN
dpc-1303	88	21	group	group	NOUN
dpc-1303	88	22	(	(	PUNCT
dpc-1303	88	23	p	p	NOUN
dpc-1303	88	24	=	=	NOUN
dpc-1303	88	25	.810	.810	NUM
dpc-1303	88	26	)	)	PUNCT
dpc-1303	88	27	.	.	PUNCT
dpc-1303	89	1	we	we	PRON
dpc-1303	89	2	did	do	AUX
dpc-1303	89	3	not	not	PART
dpc-1303	89	4	find	find	VERB
dpc-1303	89	5	any	any	DET
dpc-1303	89	6	significant	significant	ADJ
dpc-1303	89	7	difference	difference	NOUN
dpc-1303	89	8	between	between	ADP
dpc-1303	89	9	the	the	DET
dpc-1303	89	10	2	2	NUM
dpc-1303	89	11	groups	group	NOUN
dpc-1303	89	12	of	of	ADP
dpc-1303	89	13	pv	pv	NOUN
dpc-1303	89	14	patients	patient	NOUN
dpc-1303	89	15	(	(	PUNCT
dpc-1303	89	16	p	p	X
dpc-1303	89	17	=	=	NOUN
dpc-1303	89	18	.343	.343	NUM
dpc-1303	89	19	)	)	PUNCT
dpc-1303	89	20	.	.	PUNCT
dpc-1303	90	1	when	when	SCONJ
dpc-1303	90	2	the	the	DET
dpc-1303	90	3	2	2	NUM
dpc-1303	90	4	groups	group	NOUN
dpc-1303	90	5	of	of	ADP
dpc-1303	90	6	patients	patient	NOUN
dpc-1303	90	7	were	be	AUX
dpc-1303	90	8	combined	combine	VERB
dpc-1303	90	9	and	and	CCONJ
dpc-1303	90	10	considered	consider	VERB
dpc-1303	90	11	as	as	ADP
dpc-1303	90	12	a	a	DET
dpc-1303	90	13	total	total	ADJ
dpc-1303	90	14	patients	patient	NOUN
dpc-1303	90	15	group	group	NOUN
dpc-1303	90	16	,	,	PUNCT
dpc-1303	90	17	no	no	DET
dpc-1303	90	18	significant	significant	ADJ
dpc-1303	90	19	difference	difference	NOUN
dpc-1303	90	20	was	be	AUX
dpc-1303	90	21	noted	note	VERB
dpc-1303	90	22	with	with	ADP
dpc-1303	90	23	healthy	healthy	ADJ
dpc-1303	90	24	controls	control	NOUN
dpc-1303	90	25	(	(	PUNCT
dpc-1303	90	26	p	p	X
dpc-1303	90	27	=	=	NOUN
dpc-1303	90	28	.374	.374	NUM
dpc-1303	90	29	)	)	PUNCT
dpc-1303	90	30	.	.	PUNCT
dpc-1303	91	1	regarding	regard	VERB
dpc-1303	91	2	il-21	il-21	PRON
dpc-1303	91	3	,	,	PUNCT
dpc-1303	91	4	based	base	VERB
dpc-1303	91	5	on	on	ADP
dpc-1303	91	6	anova	anova	PROPN
dpc-1303	91	7	,	,	PUNCT
dpc-1303	91	8	serum	serum	NOUN
dpc-1303	91	9	levels	level	NOUN
dpc-1303	91	10	of	of	ADP
dpc-1303	91	11	il-21	il-21	NOUN
dpc-1303	91	12	were	be	AUX
dpc-1303	91	13	significantly	significantly	ADV
dpc-1303	91	14	different	different	ADJ
dpc-1303	91	15	among	among	ADP
dpc-1303	91	16	the	the	DET
dpc-1303	91	17	3	3	NUM
dpc-1303	91	18	groups	group	NOUN
dpc-1303	91	19	(	(	PUNCT
dpc-1303	91	20	p	p	X
dpc-1303	91	21	=	=	NOUN
dpc-1303	91	22	.044	.044	NUM
dpc-1303	91	23	)	)	PUNCT
dpc-1303	91	24	.	.	PUNCT
dpc-1303	92	1	we	we	PRON
dpc-1303	92	2	observed	observe	VERB
dpc-1303	92	3	a	a	DET
dpc-1303	92	4	significantly	significantly	ADV
dpc-1303	92	5	lower	low	ADJ
dpc-1303	92	6	mean	mean	NOUN
dpc-1303	92	7	serum	serum	NOUN
dpc-1303	92	8	level	level	NOUN
dpc-1303	92	9	of	of	ADP
dpc-1303	92	10	il-21	il-21	PRON
dpc-1303	92	11	in	in	ADP
dpc-1303	92	12	new	new	ADJ
dpc-1303	92	13	patients	patient	NOUN
dpc-1303	92	14	(	(	PUNCT
dpc-1303	92	15	p	p	X
dpc-1303	92	16	=	=	NOUN
dpc-1303	92	17	.005	.005	NUM
dpc-1303	92	18	)	)	PUNCT
dpc-1303	92	19	.	.	PUNCT
dpc-1303	93	1	however	however	ADV
dpc-1303	93	2	,	,	PUNCT
dpc-1303	93	3	there	there	PRON
dpc-1303	93	4	was	be	VERB
dpc-1303	93	5	no	no	DET
dpc-1303	93	6	significant	significant	ADJ
dpc-1303	93	7	difference	difference	NOUN
dpc-1303	93	8	between	between	ADP
dpc-1303	93	9	patients	patient	NOUN
dpc-1303	93	10	with	with	ADP
dpc-1303	93	11	pv	pv	NOUN
dpc-1303	93	12	in	in	ADP
dpc-1303	93	13	remission	remission	NOUN
dpc-1303	93	14	and	and	CCONJ
dpc-1303	93	15	healthy	healthy	ADJ
dpc-1303	93	16	controls	control	NOUN
dpc-1303	93	17	(	(	PUNCT
dpc-1303	93	18	p	p	X
dpc-1303	93	19	=	=	NOUN
dpc-1303	93	20	.202	.202	NUM
dpc-1303	93	21	)	)	PUNCT
dpc-1303	93	22	,	,	PUNCT
dpc-1303	93	23	as	as	ADV
dpc-1303	93	24	well	well	ADV
dpc-1303	93	25	as	as	ADP
dpc-1303	93	26	between	between	ADP
dpc-1303	93	27	the	the	DET
dpc-1303	93	28	2	2	NUM
dpc-1303	93	29	groups	group	NOUN
dpc-1303	93	30	of	of	ADP
dpc-1303	93	31	patients	patient	NOUN
dpc-1303	93	32	(	(	PUNCT
dpc-1303	93	33	p	p	X
dpc-1303	93	34	=	=	NOUN
dpc-1303	93	35	.221	.221	NUM
dpc-1303	93	36	)	)	PUNCT
dpc-1303	93	37	.	.	PUNCT
dpc-1303	94	1	interestingly	interestingly	ADV
dpc-1303	94	2	,	,	PUNCT
dpc-1303	94	3	we	we	PRON
dpc-1303	94	4	detected	detect	VERB
dpc-1303	94	5	significantly	significantly	ADV
dpc-1303	94	6	lower	low	ADJ
dpc-1303	94	7	levels	level	NOUN
dpc-1303	94	8	of	of	ADP
dpc-1303	94	9	il-21	il-21	NOUN
dpc-1303	94	10	in	in	ADP
dpc-1303	94	11	total	total	ADJ
dpc-1303	94	12	pv	pv	NOUN
dpc-1303	94	13	patients	patient	NOUN
dpc-1303	94	14	(	(	PUNCT
dpc-1303	94	15	both	both	CCONJ
dpc-1303	94	16	new	new	ADJ
dpc-1303	94	17	and	and	CCONJ
dpc-1303	94	18	remission	remission	NOUN
dpc-1303	94	19	groups	group	NOUN
dpc-1303	94	20	)	)	PUNCT
dpc-1303	94	21	than	than	ADP
dpc-1303	94	22	in	in	ADP
dpc-1303	94	23	the	the	DET
dpc-1303	94	24	healthy	healthy	ADJ
dpc-1303	94	25	controls	control	NOUN
dpc-1303	94	26	group	group	NOUN
dpc-1303	94	27	(	(	PUNCT
dpc-1303	94	28	p	p	X
dpc-1303	94	29	=	=	PROPN
dpc-1303	94	30	.027	.027	NUM
dpc-1303	94	31	)	)	PUNCT
dpc-1303	94	32	.	.	PUNCT
dpc-1303	95	1	discussion	discussion	NOUN
dpc-1303	95	2	this	this	DET
dpc-1303	95	3	study	study	NOUN
dpc-1303	95	4	shows	show	VERB
dpc-1303	95	5	that	that	SCONJ
dpc-1303	95	6	serum	serum	NOUN
dpc-1303	95	7	levels	level	NOUN
dpc-1303	95	8	of	of	ADP
dpc-1303	95	9	il-4	il-4	NOUN
dpc-1303	95	10	and	and	CCONJ
dpc-1303	95	11	il-21	il-21	NOUN
dpc-1303	95	12	are	be	AUX
dpc-1303	95	13	significantly	significantly	ADV
dpc-1303	95	14	lower	low	ADJ
dpc-1303	95	15	among	among	ADP
dpc-1303	95	16	pv	pv	PROPN
dpc-1303	95	17	patients	patient	NOUN
dpc-1303	95	18	than	than	ADP
dpc-1303	95	19	healthy	healthy	ADJ
dpc-1303	95	20	controls	control	NOUN
dpc-1303	95	21	.	.	PUNCT
dpc-1303	96	1	moreover	moreover	ADV
dpc-1303	96	2	,	,	PUNCT
dpc-1303	96	3	serum	serum	NOUN
dpc-1303	96	4	levels	level	NOUN
dpc-1303	96	5	of	of	ADP
dpc-1303	96	6	il-21	il-21	NOUN
dpc-1303	96	7	could	could	AUX
dpc-1303	96	8	be	be	AUX
dpc-1303	96	9	different	different	ADJ
dpc-1303	96	10	between	between	ADP
dpc-1303	96	11	newly	newly	ADV
dpc-1303	96	12	diagnosed	diagnose	VERB
dpc-1303	96	13	pv	pv	NOUN
dpc-1303	96	14	patients	patient	NOUN
dpc-1303	96	15	and	and	CCONJ
dpc-1303	96	16	patients	patient	NOUN
dpc-1303	96	17	with	with	ADP
dpc-1303	96	18	pv	pv	INTJ
dpc-1303	96	19	in	in	ADP
dpc-1303	96	20	remisfigure	remisfigure	NOUN
dpc-1303	96	21	1	1	NUM
dpc-1303	96	22	.	.	PUNCT
dpc-1303	97	1	serum	serum	NOUN
dpc-1303	97	2	levels	level	NOUN
dpc-1303	97	3	of	of	ADP
dpc-1303	97	4	il-4	il-4	NOUN
dpc-1303	97	5	(	(	PUNCT
dpc-1303	97	6	a	a	NOUN
dpc-1303	97	7	)	)	PUNCT
dpc-1303	97	8	and	and	CCONJ
dpc-1303	97	9	il-21	il-21	NUM
dpc-1303	97	10	(	(	PUNCT
dpc-1303	97	11	b	b	NOUN
dpc-1303	97	12	)	)	PUNCT
dpc-1303	97	13	in	in	ADP
dpc-1303	97	14	patients	patient	NOUN
dpc-1303	97	15	with	with	ADP
dpc-1303	97	16	newly	newly	ADV
dpc-1303	97	17	diagnosed	diagnose	VERB
dpc-1303	97	18	pv	pv	NOUN
dpc-1303	97	19	(	(	PUNCT
dpc-1303	97	20	“	"	PUNCT
dpc-1303	97	21	new	new	ADJ
dpc-1303	97	22	”	"	PUNCT
dpc-1303	97	23	group	group	NOUN
dpc-1303	97	24	)	)	PUNCT
dpc-1303	97	25	,	,	PUNCT
dpc-1303	97	26	patients	patient	NOUN
dpc-1303	97	27	with	with	ADP
dpc-1303	97	28	chronic	chronic	ADJ
dpc-1303	97	29	,	,	PUNCT
dpc-1303	97	30	inactive	inactive	ADJ
dpc-1303	97	31	pv	pv	NOUN
dpc-1303	97	32	(	(	PUNCT
dpc-1303	97	33	“	"	PUNCT
dpc-1303	97	34	remission	remission	NOUN
dpc-1303	97	35	”	"	PUNCT
dpc-1303	97	36	group	group	NOUN
dpc-1303	97	37	)	)	PUNCT
dpc-1303	97	38	,	,	PUNCT
dpc-1303	97	39	and	and	CCONJ
dpc-1303	97	40	healthy	healthy	ADJ
dpc-1303	97	41	controls	control	NOUN
dpc-1303	97	42	.	.	PUNCT
dpc-1303	98	1	300	300	NUM
dpc-1303	98	2	200	200	NUM
dpc-1303	98	3	100	100	NUM
dpc-1303	98	4	il	il	PROPN
dpc-1303	98	5	-4	-4	INTJ
dpc-1303	98	6	(	(	PUNCT
dpc-1303	98	7	p	p	X
dpc-1303	98	8	g	g	PROPN
dpc-1303	98	9	/m	/m	PROPN
dpc-1303	98	10	l	l	NOUN
dpc-1303	98	11	)	)	PUNCT
dpc-1303	98	12	il-4	il-4	PART
dpc-1303	99	1	-100	-100	PROPN
dpc-1303	99	2	new	new	ADJ
dpc-1303	99	3	p	p	NOUN
dpc-1303	99	4	-	-	PUNCT
dpc-1303	99	5	value	value	NOUN
dpc-1303	99	6	=	=	NOUN
dpc-1303	99	7	0.810	0.810	NUM
dpc-1303	99	8	p	p	ADJ
dpc-1303	99	9	-	-	PUNCT
dpc-1303	99	10	value	value	NOUN
dpc-1303	99	11	=	=	NOUN
dpc-1303	99	12	0.005	0.005	NUM
dpc-1303	99	13	p	p	NOUN
dpc-1303	99	14	-	-	PUNCT
dpc-1303	99	15	value	value	NOUN
dpc-1303	99	16	=	=	NOUN
dpc-1303	99	17	0.374	0.374	NUM
dpc-1303	99	18	p	p	ADJ
dpc-1303	99	19	-	-	PUNCT
dpc-1303	99	20	value	value	NOUN
dpc-1303	99	21	=	=	NOUN
dpc-1303	99	22	0.343	0.343	NUM
dpc-1303	99	23	remission	remission	NOUN
dpc-1303	99	24	healthy	healthy	ADJ
dpc-1303	99	25	controls	control	NOUN
dpc-1303	99	26	0	0	NUM
dpc-1303	99	27	il-21	il-21	ADJ
dpc-1303	99	28	p	p	PROPN
dpc-1303	99	29	-	-	PUNCT
dpc-1303	99	30	value=	value=	NOUN
dpc-1303	99	31	0.202	0.202	NUM
dpc-1303	99	32	p	p	ADJ
dpc-1303	99	33	-	-	PUNCT
dpc-1303	99	34	value	value	NOUN
dpc-1303	99	35	=	=	NOUN
dpc-1303	99	36	0.005	0.005	NUM
dpc-1303	99	37	p	p	NOUN
dpc-1303	99	38	-	-	PUNCT
dpc-1303	99	39	value	value	NOUN
dpc-1303	99	40	=	=	PUNCT
dpc-1303	99	41	0.027	0.027	NUM
dpc-1303	99	42	p	p	ADJ
dpc-1303	99	43	-	-	PUNCT
dpc-1303	99	44	value	value	NOUN
dpc-1303	99	45	=	=	NOUN
dpc-1303	99	46	0.221300	0.221300	NUM
dpc-1303	99	47	200	200	NUM
dpc-1303	99	48	100	100	NUM
dpc-1303	99	49	il	il	PROPN
dpc-1303	99	50	-2	-2	INTJ
dpc-1303	99	51	1	1	NUM
dpc-1303	99	52	(	(	PUNCT
dpc-1303	99	53	p	p	NOUN
dpc-1303	99	54	g	g	PROPN
dpc-1303	99	55	/m	/m	PROPN
dpc-1303	99	56	l	l	NOUN
dpc-1303	99	57	)	)	PUNCT
dpc-1303	99	58	-100	-100	ADP
dpc-1303	99	59	new	new	ADJ
dpc-1303	99	60	remission	remission	NOUN
dpc-1303	99	61	healthy	healthy	ADJ
dpc-1303	99	62	controls	control	NOUN
dpc-1303	99	63	0	0	NUM
dpc-1303	100	1	(	(	PUNCT
dpc-1303	100	2	a	a	NOUN
dpc-1303	100	3	)	)	PUNCT
dpc-1303	100	4	(	(	PUNCT
dpc-1303	100	5	b	b	X
dpc-1303	100	6	)	)	PUNCT
dpc-1303	100	7	research	research	NOUN
dpc-1303	100	8	|	|	ADV
dpc-1303	100	9	dermatol	dermatol	NOUN
dpc-1303	100	10	pract	pract	NOUN
dpc-1303	100	11	concept	concept	NOUN
dpc-1303	100	12	2021;11(2):e2021035	2021;11(2):e2021035	NUM
dpc-1303	100	13	5	5	NUM
dpc-1303	100	14	sion	sion	NOUN
dpc-1303	100	15	.	.	PUNCT
dpc-1303	101	1	our	our	PRON
dpc-1303	101	2	results	result	NOUN
dpc-1303	101	3	for	for	ADP
dpc-1303	101	4	il-4	il-4	NOUN
dpc-1303	101	5	imply	imply	VERB
dpc-1303	101	6	a	a	DET
dpc-1303	101	7	role	role	NOUN
dpc-1303	101	8	of	of	ADP
dpc-1303	101	9	il-4	il-4	NOUN
dpc-1303	101	10	in	in	ADP
dpc-1303	101	11	the	the	DET
dpc-1303	101	12	early	early	ADJ
dpc-1303	101	13	phase	phase	NOUN
dpc-1303	101	14	of	of	ADP
dpc-1303	101	15	the	the	DET
dpc-1303	101	16	disease	disease	NOUN
dpc-1303	101	17	,	,	PUNCT
dpc-1303	101	18	but	but	CCONJ
dpc-1303	101	19	not	not	PART
dpc-1303	101	20	in	in	ADP
dpc-1303	101	21	a	a	DET
dpc-1303	101	22	chronic	chronic	NOUN
dpc-1303	101	23	,	,	PUNCT
dpc-1303	101	24	inactive	inactive	ADJ
dpc-1303	101	25	phase	phase	NOUN
dpc-1303	101	26	of	of	ADP
dpc-1303	101	27	pv	pv	NOUN
dpc-1303	101	28	.	.	PUNCT
dpc-1303	102	1	previous	previous	ADJ
dpc-1303	102	2	studies	study	NOUN
dpc-1303	102	3	have	have	AUX
dpc-1303	102	4	suggested	suggest	VERB
dpc-1303	102	5	both	both	PRON
dpc-1303	102	6	increased	increase	VERB
dpc-1303	102	7	[	[	X
dpc-1303	102	8	17,18	17,18	X
dpc-1303	102	9	]	]	PUNCT
dpc-1303	102	10	and	and	CCONJ
dpc-1303	102	11	unchanged	unchanged	ADJ
dpc-1303	102	12	[	[	X
dpc-1303	102	13	19,20	19,20	X
dpc-1303	102	14	]	]	X
dpc-1303	102	15	serum	serum	NOUN
dpc-1303	102	16	levels	level	NOUN
dpc-1303	102	17	of	of	ADP
dpc-1303	102	18	il-4	il-4	NOUN
dpc-1303	102	19	in	in	ADP
dpc-1303	102	20	pv	pv	PROPN
dpc-1303	102	21	patients	patient	NOUN
dpc-1303	102	22	compared	compare	VERB
dpc-1303	102	23	to	to	ADP
dpc-1303	102	24	controls	control	NOUN
dpc-1303	102	25	.	.	PUNCT
dpc-1303	103	1	in	in	ADP
dpc-1303	103	2	contrast	contrast	NOUN
dpc-1303	103	3	with	with	ADP
dpc-1303	103	4	several	several	ADJ
dpc-1303	103	5	pieces	piece	NOUN
dpc-1303	103	6	of	of	ADP
dpc-1303	103	7	evidence	evidence	NOUN
dpc-1303	103	8	implying	imply	VERB
dpc-1303	103	9	pathogenic	pathogenic	ADJ
dpc-1303	103	10	roles	role	NOUN
dpc-1303	103	11	of	of	ADP
dpc-1303	103	12	il-4	il-4	NOUN
dpc-1303	103	13	[	[	X
dpc-1303	103	14	5,21	5,21	X
dpc-1303	103	15	]	]	PUNCT
dpc-1303	103	16	,	,	PUNCT
dpc-1303	103	17	we	we	PRON
dpc-1303	103	18	observed	observe	VERB
dpc-1303	103	19	lower	low	ADJ
dpc-1303	103	20	serum	serum	NOUN
dpc-1303	103	21	levels	level	NOUN
dpc-1303	103	22	in	in	ADP
dpc-1303	103	23	new	new	ADJ
dpc-1303	103	24	patients	patient	NOUN
dpc-1303	103	25	than	than	ADP
dpc-1303	103	26	in	in	ADP
dpc-1303	103	27	healthy	healthy	ADJ
dpc-1303	103	28	controls	control	NOUN
dpc-1303	103	29	.	.	PUNCT
dpc-1303	104	1	regarding	regard	VERB
dpc-1303	104	2	il-21	il-21	PRON
dpc-1303	104	3	,	,	PUNCT
dpc-1303	104	4	we	we	PRON
dpc-1303	104	5	again	again	ADV
dpc-1303	104	6	found	find	VERB
dpc-1303	104	7	surprising	surprising	ADJ
dpc-1303	104	8	results	result	NOUN
dpc-1303	104	9	that	that	PRON
dpc-1303	104	10	were	be	AUX
dpc-1303	104	11	different	different	ADJ
dpc-1303	104	12	from	from	ADP
dpc-1303	104	13	what	what	PRON
dpc-1303	104	14	we	we	PRON
dpc-1303	104	15	expected	expect	VERB
dpc-1303	104	16	.	.	PUNCT
dpc-1303	105	1	although	although	SCONJ
dpc-1303	105	2	there	there	PRON
dpc-1303	105	3	is	be	VERB
dpc-1303	105	4	no	no	DET
dpc-1303	105	5	study	study	NOUN
dpc-1303	105	6	on	on	ADP
dpc-1303	105	7	serum	serum	NOUN
dpc-1303	105	8	levels	level	NOUN
dpc-1303	105	9	of	of	ADP
dpc-1303	105	10	il-21	il-21	NOUN
dpc-1303	105	11	in	in	ADP
dpc-1303	105	12	pv	pv	PROPN
dpc-1303	105	13	patients	patient	NOUN
dpc-1303	105	14	,	,	PUNCT
dpc-1303	105	15	there	there	PRON
dpc-1303	105	16	is	be	VERB
dpc-1303	105	17	some	some	DET
dpc-1303	105	18	evidence	evidence	NOUN
dpc-1303	105	19	of	of	ADP
dpc-1303	105	20	the	the	DET
dpc-1303	105	21	pathogenic	pathogenic	ADJ
dpc-1303	105	22	role	role	NOUN
dpc-1303	105	23	of	of	ADP
dpc-1303	105	24	il-21	il-21	NOUN
dpc-1303	105	25	in	in	ADP
dpc-1303	105	26	pv	pv	INTJ
dpc-1303	105	27	.	.	PUNCT
dpc-1303	106	1	yuan	yuan	NOUN
dpc-1303	106	2	et	et	PROPN
dpc-1303	106	3	al	al	PROPN
dpc-1303	106	4	showed	show	VERB
dpc-1303	106	5	that	that	SCONJ
dpc-1303	106	6	most	most	ADJ
dpc-1303	106	7	t	t	NOUN
dpc-1303	106	8	lymphocytes	lymphocyte	VERB
dpc-1303	106	9	infiltrating	infiltrate	VERB
dpc-1303	106	10	pv	pv	NOUN
dpc-1303	106	11	lesions	lesion	NOUN
dpc-1303	106	12	were	be	AUX
dpc-1303	106	13	cd4	cd4	PROPN
dpc-1303	106	14	+	+	PROPN
dpc-1303	106	15	t	t	PROPN
dpc-1303	106	16	helper	helper	NOUN
dpc-1303	106	17	cells	cell	NOUN
dpc-1303	106	18	expressing	express	VERB
dpc-1303	106	19	il-21	il-21	PRON
dpc-1303	106	20	[	[	X
dpc-1303	106	21	22	22	NUM
dpc-1303	106	22	]	]	PUNCT
dpc-1303	106	23	.	.	PUNCT
dpc-1303	107	1	moreover	moreover	ADV
dpc-1303	107	2	,	,	PUNCT
dpc-1303	107	3	not	not	PART
dpc-1303	107	4	only	only	ADV
dpc-1303	107	5	elevated	elevated	ADJ
dpc-1303	107	6	plasma	plasma	NOUN
dpc-1303	107	7	il-21	il-21	PUNCT
dpc-1303	107	8	concentrations	concentration	NOUN
dpc-1303	107	9	have	have	AUX
dpc-1303	107	10	been	be	AUX
dpc-1303	107	11	reported	report	VERB
dpc-1303	107	12	in	in	ADP
dpc-1303	107	13	pv	pv	NOUN
dpc-1303	107	14	patients	patient	NOUN
dpc-1303	107	15	,	,	PUNCT
dpc-1303	107	16	but	but	CCONJ
dpc-1303	107	17	also	also	ADV
dpc-1303	107	18	dsg3	dsg3	ADJ
dpc-1303	107	19	-	-	PUNCT
dpc-1303	107	20	specific	specific	ADJ
dpc-1303	107	21	autoreactive	autoreactive	ADJ
dpc-1303	107	22	t	t	NOUN
dpc-1303	107	23	cells	cell	NOUN
dpc-1303	107	24	producing	produce	VERB
dpc-1303	107	25	il-21	il-21	NOUN
dpc-1303	107	26	were	be	AUX
dpc-1303	107	27	detected	detect	VERB
dpc-1303	107	28	upon	upon	SCONJ
dpc-1303	107	29	ex	ex	PRON
dpc-1303	107	30	vivo	vivo	ADJ
dpc-1303	107	31	stimulation	stimulation	NOUN
dpc-1303	107	32	with	with	ADP
dpc-1303	107	33	dsg3	dsg3	PROPN
dpc-1303	108	1	[	[	X
dpc-1303	108	2	11	11	NUM
dpc-1303	108	3	]	]	PUNCT
dpc-1303	108	4	.	.	PUNCT
dpc-1303	109	1	all	all	DET
dpc-1303	109	2	this	this	DET
dpc-1303	109	3	evidence	evidence	NOUN
dpc-1303	109	4	led	lead	VERB
dpc-1303	109	5	to	to	ADP
dpc-1303	109	6	suggesting	suggest	VERB
dpc-1303	109	7	a	a	DET
dpc-1303	109	8	possible	possible	ADJ
dpc-1303	109	9	pathogenic	pathogenic	ADJ
dpc-1303	109	10	role	role	NOUN
dpc-1303	109	11	of	of	ADP
dpc-1303	109	12	il-21	il-21	PRON
dpc-1303	109	13	in	in	ADP
dpc-1303	109	14	pemphigus	pemphigus	NOUN
dpc-1303	109	15	[	[	X
dpc-1303	109	16	7	7	NUM
dpc-1303	109	17	]	]	PUNCT
dpc-1303	109	18	.	.	PUNCT
dpc-1303	110	1	additionally	additionally	ADV
dpc-1303	110	2	,	,	PUNCT
dpc-1303	110	3	in	in	ADP
dpc-1303	110	4	our	our	PRON
dpc-1303	110	5	recent	recent	ADJ
dpc-1303	110	6	study	study	NOUN
dpc-1303	110	7	[	[	X
dpc-1303	110	8	23	23	NUM
dpc-1303	110	9	]	]	PUNCT
dpc-1303	110	10	on	on	ADP
dpc-1303	110	11	the	the	DET
dpc-1303	110	12	evaluation	evaluation	NOUN
dpc-1303	110	13	of	of	ADP
dpc-1303	110	14	il21	il21	PROPN
dpc-1303	110	15	gene	gene	NOUN
dpc-1303	110	16	expression	expression	NOUN
dpc-1303	110	17	at	at	ADP
dpc-1303	110	18	the	the	DET
dpc-1303	110	19	transcription	transcription	NOUN
dpc-1303	110	20	level	level	NOUN
dpc-1303	110	21	,	,	PUNCT
dpc-1303	110	22	we	we	PRON
dpc-1303	110	23	did	do	AUX
dpc-1303	110	24	not	not	PART
dpc-1303	110	25	find	find	VERB
dpc-1303	110	26	any	any	DET
dpc-1303	110	27	difference	difference	NOUN
dpc-1303	110	28	between	between	ADP
dpc-1303	110	29	pemphigus	pemphigus	NOUN
dpc-1303	110	30	patients	patient	NOUN
dpc-1303	110	31	and	and	CCONJ
dpc-1303	110	32	healthy	healthy	ADJ
dpc-1303	110	33	controls	control	NOUN
dpc-1303	110	34	.	.	PUNCT
dpc-1303	111	1	however	however	ADV
dpc-1303	111	2	,	,	PUNCT
dpc-1303	111	3	3	3	NUM
dpc-1303	111	4	months	month	NOUN
dpc-1303	111	5	after	after	ADP
dpc-1303	111	6	rituximab	rituximab	NOUN
dpc-1303	111	7	administration	administration	PROPN
dpc-1303	111	8	,	,	PUNCT
dpc-1303	111	9	the	the	DET
dpc-1303	111	10	expression	expression	NOUN
dpc-1303	111	11	of	of	ADP
dpc-1303	111	12	il21	il21	PROPN
dpc-1303	111	13	had	have	AUX
dpc-1303	111	14	increased	increase	VERB
dpc-1303	111	15	.	.	PUNCT
dpc-1303	112	1	these	these	DET
dpc-1303	112	2	controversies	controversy	NOUN
dpc-1303	112	3	between	between	ADP
dpc-1303	112	4	previous	previous	ADJ
dpc-1303	112	5	studies	study	NOUN
dpc-1303	112	6	and	and	CCONJ
dpc-1303	112	7	the	the	DET
dpc-1303	112	8	current	current	ADJ
dpc-1303	112	9	study	study	NOUN
dpc-1303	112	10	might	might	AUX
dpc-1303	112	11	be	be	AUX
dpc-1303	112	12	due	due	ADJ
dpc-1303	112	13	to	to	ADP
dpc-1303	112	14	this	this	DET
dpc-1303	112	15	study	study	NOUN
dpc-1303	112	16	’s	’s	PART
dpc-1303	112	17	limitations	limitation	NOUN
dpc-1303	112	18	or	or	CCONJ
dpc-1303	112	19	even	even	ADV
dpc-1303	112	20	suggest	suggest	VERB
dpc-1303	112	21	a	a	DET
dpc-1303	112	22	high	high	ADJ
dpc-1303	112	23	heterogeneity	heterogeneity	NOUN
dpc-1303	112	24	of	of	ADP
dpc-1303	112	25	pv	pv	INTJ
dpc-1303	112	26	,	,	PUNCT
dpc-1303	112	27	which	which	PRON
dpc-1303	112	28	could	could	AUX
dpc-1303	112	29	be	be	AUX
dpc-1303	112	30	managed	manage	VERB
dpc-1303	112	31	with	with	ADP
dpc-1303	112	32	the	the	DET
dpc-1303	112	33	view	view	NOUN
dpc-1303	112	34	of	of	ADP
dpc-1303	112	35	personalized	personalized	ADJ
dpc-1303	112	36	medicine	medicine	NOUN
dpc-1303	112	37	[	[	X
dpc-1303	112	38	23	23	NUM
dpc-1303	112	39	]	]	PUNCT
dpc-1303	112	40	.	.	PUNCT
dpc-1303	113	1	although	although	SCONJ
dpc-1303	113	2	we	we	PRON
dpc-1303	113	3	did	do	AUX
dpc-1303	113	4	not	not	PART
dpc-1303	113	5	find	find	VERB
dpc-1303	113	6	any	any	DET
dpc-1303	113	7	significant	significant	ADJ
dpc-1303	113	8	differences	difference	NOUN
dpc-1303	113	9	in	in	ADP
dpc-1303	113	10	the	the	DET
dpc-1303	113	11	cytokines	cytokine	NOUN
dpc-1303	113	12	between	between	ADP
dpc-1303	113	13	the	the	DET
dpc-1303	113	14	2	2	NUM
dpc-1303	113	15	groups	group	NOUN
dpc-1303	113	16	of	of	ADP
dpc-1303	113	17	pv	pv	NOUN
dpc-1303	113	18	patients	patient	NOUN
dpc-1303	113	19	,	,	PUNCT
dpc-1303	113	20	different	different	ADJ
dpc-1303	113	21	cytokine	cytokine	NOUN
dpc-1303	113	22	profiles	profile	NOUN
dpc-1303	113	23	during	during	ADP
dpc-1303	113	24	the	the	DET
dpc-1303	113	25	disease	disease	NOUN
dpc-1303	113	26	phases	phase	NOUN
dpc-1303	113	27	are	be	AUX
dpc-1303	113	28	plausible	plausible	ADJ
dpc-1303	113	29	.	.	PUNCT
dpc-1303	114	1	in	in	ADP
dpc-1303	114	2	addition	addition	NOUN
dpc-1303	114	3	,	,	PUNCT
dpc-1303	114	4	treatment	treatment	NOUN
dpc-1303	114	5	,	,	PUNCT
dpc-1303	114	6	previous	previous	ADJ
dpc-1303	114	7	exposure	exposure	NOUN
dpc-1303	114	8	to	to	ADP
dpc-1303	114	9	certain	certain	ADJ
dpc-1303	114	10	biologics	biologic	NOUN
dpc-1303	114	11	(	(	PUNCT
dpc-1303	114	12	eg	eg	NOUN
dpc-1303	114	13	,	,	PUNCT
dpc-1303	114	14	rituximab	rituximab	NOUN
dpc-1303	114	15	)	)	PUNCT
dpc-1303	114	16	,	,	PUNCT
dpc-1303	114	17	and	and	CCONJ
dpc-1303	114	18	duration	duration	NOUN
dpc-1303	114	19	of	of	ADP
dpc-1303	114	20	disease	disease	NOUN
dpc-1303	114	21	could	could	AUX
dpc-1303	114	22	change	change	VERB
dpc-1303	114	23	the	the	DET
dpc-1303	114	24	cytokine	cytokine	ADJ
dpc-1303	114	25	profiles	profile	NOUN
dpc-1303	114	26	of	of	ADP
dpc-1303	114	27	the	the	DET
dpc-1303	114	28	patients	patient	NOUN
dpc-1303	114	29	.	.	PUNCT
dpc-1303	115	1	for	for	ADP
dpc-1303	115	2	example	example	NOUN
dpc-1303	115	3	,	,	PUNCT
dpc-1303	115	4	in	in	ADP
dpc-1303	115	5	our	our	PRON
dpc-1303	115	6	recent	recent	ADJ
dpc-1303	115	7	study	study	NOUN
dpc-1303	115	8	,	,	PUNCT
dpc-1303	115	9	we	we	PRON
dpc-1303	115	10	showed	show	VERB
dpc-1303	115	11	that	that	SCONJ
dpc-1303	115	12	,	,	PUNCT
dpc-1303	115	13	3	3	NUM
dpc-1303	115	14	months	month	NOUN
dpc-1303	115	15	after	after	SCONJ
dpc-1303	115	16	rituximab	rituximab	NOUN
dpc-1303	115	17	administration	administration	PROPN
dpc-1303	115	18	,	,	PUNCT
dpc-1303	115	19	the	the	DET
dpc-1303	115	20	expression	expression	NOUN
dpc-1303	115	21	of	of	ADP
dpc-1303	115	22	ebi3	ebi3	PROPN
dpc-1303	115	23	,	,	PUNCT
dpc-1303	115	24	pdcd1	pdcd1	NOUN
dpc-1303	115	25	,	,	PUNCT
dpc-1303	115	26	il21	il21	PROPN
dpc-1303	115	27	and	and	CCONJ
dpc-1303	115	28	il22	il22	PROPN
dpc-1303	115	29	had	have	AUX
dpc-1303	115	30	increased	increase	VERB
dpc-1303	115	31	(	(	PUNCT
dpc-1303	115	32	24	24	NUM
dpc-1303	115	33	]	]	PUNCT
dpc-1303	115	34	.	.	PUNCT
dpc-1303	116	1	additionally	additionally	ADV
dpc-1303	116	2	,	,	PUNCT
dpc-1303	116	3	in	in	ADP
dpc-1303	116	4	another	another	DET
dpc-1303	116	5	study	study	NOUN
dpc-1303	116	6	,	,	PUNCT
dpc-1303	116	7	we	we	PRON
dpc-1303	116	8	showed	show	VERB
dpc-1303	116	9	that	that	SCONJ
dpc-1303	116	10	the	the	DET
dpc-1303	116	11	outcome	outcome	NOUN
dpc-1303	116	12	of	of	ADP
dpc-1303	116	13	treatment	treatment	NOUN
dpc-1303	116	14	with	with	ADP
dpc-1303	116	15	rituximab	rituximab	NOUN
dpc-1303	116	16	was	be	AUX
dpc-1303	116	17	different	different	ADJ
dpc-1303	116	18	between	between	ADP
dpc-1303	116	19	patients	patient	NOUN
dpc-1303	116	20	treated	treat	VERB
dpc-1303	116	21	early	early	ADV
dpc-1303	116	22	or	or	CCONJ
dpc-1303	116	23	late	late	ADJ
dpc-1303	116	24	[	[	X
dpc-1303	116	25	25	25	NUM
dpc-1303	116	26	]	]	PUNCT
dpc-1303	116	27	.	.	PUNCT
dpc-1303	117	1	this	this	DET
dpc-1303	117	2	finding	finding	NOUN
dpc-1303	117	3	might	might	AUX
dpc-1303	117	4	be	be	AUX
dpc-1303	117	5	explained	explain	VERB
dpc-1303	117	6	by	by	ADP
dpc-1303	117	7	switching	switch	VERB
dpc-1303	117	8	between	between	ADP
dpc-1303	117	9	the	the	DET
dpc-1303	117	10	immune	immune	ADJ
dpc-1303	117	11	responses	response	NOUN
dpc-1303	117	12	’	'	PUNCT
dpc-1303	117	13	arms	arm	NOUN
dpc-1303	117	14	as	as	SCONJ
dpc-1303	117	15	time	time	NOUN
dpc-1303	117	16	passes	pass	VERB
dpc-1303	117	17	or	or	CCONJ
dpc-1303	117	18	might	might	AUX
dpc-1303	117	19	depend	depend	VERB
dpc-1303	117	20	on	on	ADP
dpc-1303	117	21	the	the	DET
dpc-1303	117	22	exposure	exposure	NOUN
dpc-1303	117	23	to	to	ADP
dpc-1303	117	24	certain	certain	ADJ
dpc-1303	117	25	therapeutic	therapeutic	ADJ
dpc-1303	117	26	agents	agent	NOUN
dpc-1303	117	27	.	.	PUNCT
dpc-1303	118	1	in	in	ADP
dpc-1303	118	2	this	this	DET
dpc-1303	118	3	study	study	NOUN
dpc-1303	118	4	,	,	PUNCT
dpc-1303	118	5	we	we	PRON
dpc-1303	118	6	tried	try	VERB
dpc-1303	118	7	to	to	PART
dpc-1303	118	8	minimize	minimize	VERB
dpc-1303	118	9	the	the	DET
dpc-1303	118	10	effects	effect	NOUN
dpc-1303	118	11	of	of	ADP
dpc-1303	118	12	treatment	treatment	NOUN
dpc-1303	118	13	by	by	ADP
dpc-1303	118	14	including	include	VERB
dpc-1303	118	15	only	only	ADJ
dpc-1303	118	16	patients	patient	NOUN
dpc-1303	118	17	who	who	PRON
dpc-1303	118	18	were	be	AUX
dpc-1303	118	19	off	off	ADP
dpc-1303	118	20	therapy	therapy	NOUN
dpc-1303	118	21	or	or	CCONJ
dpc-1303	118	22	on	on	ADP
dpc-1303	118	23	minimal	minimal	ADJ
dpc-1303	118	24	therapy	therapy	NOUN
dpc-1303	118	25	.	.	PUNCT
dpc-1303	119	1	however	however	ADV
dpc-1303	119	2	,	,	PUNCT
dpc-1303	119	3	this	this	DET
dpc-1303	119	4	study	study	NOUN
dpc-1303	119	5	still	still	ADV
dpc-1303	119	6	has	have	VERB
dpc-1303	119	7	some	some	DET
dpc-1303	119	8	limitations	limitation	NOUN
dpc-1303	119	9	,	,	PUNCT
dpc-1303	119	10	which	which	PRON
dpc-1303	119	11	should	should	AUX
dpc-1303	119	12	be	be	AUX
dpc-1303	119	13	addressed	address	VERB
dpc-1303	119	14	.	.	PUNCT
dpc-1303	120	1	firstly	firstly	ADV
dpc-1303	120	2	,	,	PUNCT
dpc-1303	120	3	patients	patient	NOUN
dpc-1303	120	4	in	in	ADP
dpc-1303	120	5	the	the	DET
dpc-1303	120	6	pv	pv	NOUN
dpc-1303	120	7	in	in	ADP
dpc-1303	120	8	remission	remission	NOUN
dpc-1303	120	9	group	group	NOUN
dpc-1303	120	10	were	be	AUX
dpc-1303	120	11	not	not	PART
dpc-1303	120	12	homogeneous	homogeneous	ADJ
dpc-1303	120	13	.	.	PUNCT
dpc-1303	121	1	in	in	ADP
dpc-1303	121	2	fact	fact	NOUN
dpc-1303	121	3	,	,	PUNCT
dpc-1303	121	4	they	they	PRON
dpc-1303	121	5	were	be	AUX
dpc-1303	121	6	either	either	CCONJ
dpc-1303	121	7	in	in	ADP
dpc-1303	121	8	complete	complete	ADJ
dpc-1303	121	9	or	or	CCONJ
dpc-1303	121	10	incomplete	incomplete	ADJ
dpc-1303	121	11	remission	remission	NOUN
dpc-1303	121	12	.	.	PUNCT
dpc-1303	122	1	secondly	secondly	ADV
dpc-1303	122	2	,	,	PUNCT
dpc-1303	122	3	the	the	DET
dpc-1303	122	4	majority	majority	NOUN
dpc-1303	122	5	of	of	ADP
dpc-1303	122	6	blood	blood	NOUN
dpc-1303	122	7	samples	sample	NOUN
dpc-1303	122	8	in	in	ADP
dpc-1303	122	9	the	the	DET
dpc-1303	122	10	control	control	NOUN
dpc-1303	122	11	group	group	NOUN
dpc-1303	122	12	were	be	AUX
dpc-1303	122	13	taken	take	VERB
dpc-1303	122	14	from	from	ADP
dpc-1303	122	15	parents	parent	NOUN
dpc-1303	122	16	or	or	CCONJ
dpc-1303	122	17	siblings	sibling	NOUN
dpc-1303	122	18	of	of	ADP
dpc-1303	122	19	the	the	DET
dpc-1303	122	20	patients	patient	NOUN
dpc-1303	122	21	.	.	PUNCT
dpc-1303	123	1	therefore	therefore	ADV
dpc-1303	123	2	,	,	PUNCT
dpc-1303	123	3	because	because	SCONJ
dpc-1303	123	4	of	of	ADP
dpc-1303	123	5	their	their	PRON
dpc-1303	123	6	similar	similar	ADJ
dpc-1303	123	7	genetic	genetic	ADJ
dpc-1303	123	8	backgrounds	background	NOUN
dpc-1303	123	9	,	,	PUNCT
dpc-1303	123	10	these	these	DET
dpc-1303	123	11	samples	sample	NOUN
dpc-1303	123	12	might	might	AUX
dpc-1303	123	13	have	have	AUX
dpc-1303	123	14	introduced	introduce	VERB
dpc-1303	123	15	some	some	DET
dpc-1303	123	16	errors	error	NOUN
dpc-1303	123	17	in	in	ADP
dpc-1303	123	18	the	the	DET
dpc-1303	123	19	results	result	NOUN
dpc-1303	123	20	and	and	CCONJ
dpc-1303	123	21	might	might	AUX
dpc-1303	123	22	not	not	PART
dpc-1303	123	23	be	be	AUX
dpc-1303	123	24	representative	representative	ADJ
dpc-1303	123	25	of	of	ADP
dpc-1303	123	26	the	the	DET
dpc-1303	123	27	healthy	healthy	ADJ
dpc-1303	123	28	population	population	NOUN
dpc-1303	123	29	.	.	PUNCT
dpc-1303	124	1	thirdly	thirdly	ADV
dpc-1303	124	2	,	,	PUNCT
dpc-1303	124	3	the	the	DET
dpc-1303	124	4	severity	severity	NOUN
dpc-1303	124	5	of	of	ADP
dpc-1303	124	6	patients	patient	NOUN
dpc-1303	124	7	’	'	PUNCT
dpc-1303	124	8	disease	disease	NOUN
dpc-1303	124	9	was	be	AUX
dpc-1303	124	10	not	not	PART
dpc-1303	124	11	considered	consider	VERB
dpc-1303	124	12	.	.	PUNCT
dpc-1303	125	1	calculation	calculation	NOUN
dpc-1303	125	2	of	of	ADP
dpc-1303	125	3	pdai	pdai	PROPN
dpc-1303	125	4	scores	score	NOUN
dpc-1303	125	5	,	,	PUNCT
dpc-1303	125	6	measurement	measurement	NOUN
dpc-1303	125	7	of	of	ADP
dpc-1303	125	8	anti	anti	NOUN
dpc-1303	125	9	-	-	ADJ
dpc-1303	125	10	dsg1	dsg1	NOUN
dpc-1303	125	11	and	and	CCONJ
dpc-1303	125	12	anti	anti	ADJ
dpc-1303	125	13	-	-	ADJ
dpc-1303	125	14	dsg3	dsg3	ADJ
dpc-1303	125	15	levels	level	NOUN
dpc-1303	125	16	,	,	PUNCT
dpc-1303	125	17	and	and	CCONJ
dpc-1303	125	18	evaluation	evaluation	NOUN
dpc-1303	125	19	of	of	ADP
dpc-1303	125	20	their	their	PRON
dpc-1303	125	21	associations	association	NOUN
dpc-1303	125	22	with	with	ADP
dpc-1303	125	23	serum	serum	NOUN
dpc-1303	125	24	cytokines	cytokine	NOUN
dpc-1303	125	25	in	in	ADP
dpc-1303	125	26	a	a	DET
dpc-1303	125	27	study	study	NOUN
dpc-1303	125	28	with	with	ADP
dpc-1303	125	29	a	a	DET
dpc-1303	125	30	larger	large	ADJ
dpc-1303	125	31	number	number	NOUN
dpc-1303	125	32	of	of	ADP
dpc-1303	125	33	patients	patient	NOUN
dpc-1303	125	34	are	be	AUX
dpc-1303	125	35	recommended	recommend	VERB
dpc-1303	125	36	for	for	ADP
dpc-1303	125	37	future	future	ADJ
dpc-1303	125	38	studies	study	NOUN
dpc-1303	125	39	.	.	PUNCT
dpc-1303	126	1	conclusions	conclusion	NOUN
dpc-1303	126	2	in	in	ADP
dpc-1303	126	3	conclusion	conclusion	NOUN
dpc-1303	126	4	,	,	PUNCT
dpc-1303	126	5	due	due	ADP
dpc-1303	126	6	to	to	ADP
dpc-1303	126	7	significantly	significantly	ADV
dpc-1303	126	8	different	different	ADJ
dpc-1303	126	9	serum	serum	NOUN
dpc-1303	126	10	levels	level	NOUN
dpc-1303	126	11	of	of	ADP
dpc-1303	126	12	il-4	il-4	NOUN
dpc-1303	126	13	and	and	CCONJ
dpc-1303	126	14	il-21	il-21	X
dpc-1303	126	15	among	among	ADP
dpc-1303	126	16	the	the	DET
dpc-1303	126	17	newly	newly	ADV
dpc-1303	126	18	diagnosed	diagnose	VERB
dpc-1303	126	19	pv	pv	NOUN
dpc-1303	126	20	patients	patient	NOUN
dpc-1303	126	21	and	and	CCONJ
dpc-1303	126	22	healthy	healthy	ADJ
dpc-1303	126	23	controls	control	NOUN
dpc-1303	126	24	,	,	PUNCT
dpc-1303	126	25	it	it	PRON
dpc-1303	126	26	can	can	AUX
dpc-1303	126	27	be	be	AUX
dpc-1303	126	28	speculated	speculate	VERB
dpc-1303	126	29	that	that	SCONJ
dpc-1303	126	30	these	these	DET
dpc-1303	126	31	cytokines	cytokine	NOUN
dpc-1303	126	32	are	be	AUX
dpc-1303	126	33	involved	involve	VERB
dpc-1303	126	34	in	in	ADP
dpc-1303	126	35	the	the	DET
dpc-1303	126	36	development	development	NOUN
dpc-1303	126	37	and	and	CCONJ
dpc-1303	126	38	pathogenesis	pathogenesis	NOUN
dpc-1303	126	39	of	of	ADP
dpc-1303	126	40	pv	pv	INTJ
dpc-1303	126	41	.	.	PUNCT
dpc-1303	127	1	however	however	ADV
dpc-1303	127	2	,	,	PUNCT
dpc-1303	127	3	according	accord	VERB
dpc-1303	127	4	to	to	ADP
dpc-1303	127	5	the	the	DET
dpc-1303	127	6	literature	literature	NOUN
dpc-1303	127	7	and	and	CCONJ
dpc-1303	127	8	due	due	ADP
dpc-1303	127	9	to	to	ADP
dpc-1303	127	10	the	the	DET
dpc-1303	127	11	mentioned	mention	VERB
dpc-1303	127	12	limitations	limitation	NOUN
dpc-1303	127	13	of	of	ADP
dpc-1303	127	14	this	this	DET
dpc-1303	127	15	study	study	NOUN
dpc-1303	127	16	,	,	PUNCT
dpc-1303	127	17	especially	especially	ADV
dpc-1303	127	18	the	the	DET
dpc-1303	127	19	selection	selection	NOUN
dpc-1303	127	20	of	of	ADP
dpc-1303	127	21	controls	control	NOUN
dpc-1303	127	22	,	,	PUNCT
dpc-1303	127	23	our	our	PRON
dpc-1303	127	24	results	result	NOUN
dpc-1303	127	25	,	,	PUNCT
dpc-1303	127	26	especially	especially	ADV
dpc-1303	127	27	the	the	DET
dpc-1303	127	28	lower	low	ADJ
dpc-1303	127	29	level	level	NOUN
dpc-1303	127	30	of	of	ADP
dpc-1303	127	31	these	these	DET
dpc-1303	127	32	cytokines	cytokine	NOUN
dpc-1303	127	33	in	in	ADP
dpc-1303	127	34	patients	patient	NOUN
dpc-1303	127	35	than	than	ADP
dpc-1303	127	36	in	in	ADP
dpc-1303	127	37	controls	control	NOUN
dpc-1303	127	38	,	,	PUNCT
dpc-1303	127	39	might	might	AUX
dpc-1303	127	40	not	not	PART
dpc-1303	127	41	be	be	AUX
dpc-1303	127	42	absolutely	absolutely	ADV
dpc-1303	127	43	trustable	trustable	ADJ
dpc-1303	127	44	.	.	PUNCT
dpc-1303	128	1	therefore	therefore	ADV
dpc-1303	128	2	,	,	PUNCT
dpc-1303	128	3	future	future	ADJ
dpc-1303	128	4	studies	study	NOUN
dpc-1303	128	5	without	without	ADP
dpc-1303	128	6	the	the	DET
dpc-1303	128	7	mentioned	mention	VERB
dpc-1303	128	8	limitations	limitation	NOUN
dpc-1303	128	9	are	be	AUX
dpc-1303	128	10	required	require	VERB
dpc-1303	128	11	.	.	PUNCT
dpc-1303	129	1	acknowledgment	acknowledgment	NOUN
dpc-1303	129	2	this	this	DET
dpc-1303	129	3	research	research	NOUN
dpc-1303	129	4	was	be	AUX
dpc-1303	129	5	supported	support	VERB
dpc-1303	129	6	by	by	ADP
dpc-1303	129	7	tehran	tehran	PROPN
dpc-1303	129	8	university	university	PROPN
dpc-1303	129	9	of	of	ADP
dpc-1303	129	10	medical	medical	PROPN
dpc-1303	129	11	sciences	sciences	PROPN
dpc-1303	129	12	(	(	PUNCT
dpc-1303	129	13	tums	tum	NOUN
dpc-1303	129	14	)	)	PUNCT
dpc-1303	129	15	;	;	PUNCT
dpc-1303	129	16	grant	grant	VERB
dpc-1303	129	17	no	no	NOUN
dpc-1303	129	18	.	.	NOUN
dpc-1303	130	1	96	96	NUM
dpc-1303	130	2	-	-	PUNCT
dpc-1303	130	3	01	01	NUM
dpc-1303	130	4	-	-	PUNCT
dpc-1303	130	5	101	101	NUM
dpc-1303	130	6	-	-	PUNCT
dpc-1303	130	7	33881	33881	NUM
dpc-1303	130	8	.	.	PUNCT
dpc-1303	131	1	references	reference	NOUN
dpc-1303	131	2	1	1	NUM
dpc-1303	131	3	.	.	PUNCT
dpc-1303	131	4	amber	amber	PROPN
dpc-1303	131	5	kt	kt	PROPN
dpc-1303	131	6	,	,	PUNCT
dpc-1303	131	7	staropoli	staropoli	PROPN
dpc-1303	131	8	p	p	NOUN
dpc-1303	131	9	,	,	PUNCT
dpc-1303	131	10	shiman	shiman	PROPN
dpc-1303	131	11	mi	mi	PROPN
dpc-1303	131	12	,	,	PUNCT
dpc-1303	131	13	elgart	elgart	NOUN
dpc-1303	131	14	gw	gw	PROPN
dpc-1303	131	15	,	,	PUNCT
dpc-1303	131	16	hertl	hertl	NOUN
dpc-1303	131	17	m.	m.	NOUN
dpc-1303	131	18	autoreactive	autoreactive	PROPN
dpc-1303	131	19	t	t	PROPN
dpc-1303	131	20	cells	cell	NOUN
dpc-1303	131	21	in	in	ADP
dpc-1303	131	22	the	the	DET
dpc-1303	131	23	immune	immune	ADJ
dpc-1303	131	24	pathogenesis	pathogenesis	NOUN
dpc-1303	131	25	of	of	ADP
dpc-1303	131	26	pemphigus	pemphigus	NOUN
dpc-1303	131	27	vulgaris	vulgaris	NOUN
dpc-1303	131	28	.	.	PUNCT
dpc-1303	132	1	exp	exp	NOUN
dpc-1303	132	2	dermatol	dermatol	NOUN
dpc-1303	132	3	.	.	PUNCT
dpc-1303	133	1	2013;22(11):699	2013;22(11):699	NUM
dpc-1303	133	2	-	-	PUNCT
dpc-1303	133	3	704	704	NUM
dpc-1303	133	4	.	.	PUNCT
dpc-1303	134	1	doi	doi	NOUN
dpc-1303	134	2	:	:	PUNCT
dpc-1303	134	3	10.1111	10.1111	NUM
dpc-1303	134	4	/	/	SYM
dpc-1303	134	5	exd.12229	exd.12229	PROPN
dpc-1303	134	6	.	.	PUNCT
dpc-1303	135	1	pmid	pmid	NOUN
dpc-1303	135	2	:	:	PUNCT
dpc-1303	135	3	24433179	24433179	NUM
dpc-1303	135	4	.	.	PUNCT
dpc-1303	136	1	2	2	X
dpc-1303	136	2	.	.	X
dpc-1303	136	3	fang	fang	PROPN
dpc-1303	136	4	h	h	PROPN
dpc-1303	136	5	,	,	PUNCT
dpc-1303	136	6	li	li	PROPN
dpc-1303	136	7	q	q	PROPN
dpc-1303	136	8	,	,	PUNCT
dpc-1303	136	9	wang	wang	PROPN
dpc-1303	136	10	g.	g.	PROPN
dpc-1303	136	11	the	the	DET
dpc-1303	136	12	role	role	NOUN
dpc-1303	136	13	of	of	ADP
dpc-1303	136	14	t	t	NOUN
dpc-1303	136	15	cells	cell	NOUN
dpc-1303	136	16	in	in	ADP
dpc-1303	136	17	pemphigus	pemphigus	NOUN
dpc-1303	136	18	vulgaris	vulgaris	NOUN
dpc-1303	136	19	and	and	CCONJ
dpc-1303	136	20	bullous	bullous	ADJ
dpc-1303	136	21	pemphigoid	pemphigoid	NOUN
dpc-1303	136	22	.	.	PUNCT
dpc-1303	137	1	autoimm	autoimm	PROPN
dpc-1303	137	2	rev	rev	VERB
dpc-1303	137	3	.	.	PROPN
dpc-1303	137	4	2020:102661	2020:102661	NUM
dpc-1303	137	5	.	.	PUNCT
dpc-1303	138	1	doi	doi	NOUN
dpc-1303	138	2	:	:	PUNCT
dpc-1303	138	3	10.1016	10.1016	NUM
dpc-1303	138	4	/	/	SYM
dpc-1303	138	5	j.autrev.2020.102661	j.autrev.2020.102661	PROPN
dpc-1303	138	6	.	.	PUNCT
dpc-1303	139	1	pmid	pmid	NOUN
dpc-1303	139	2	:	:	PUNCT
dpc-1303	139	3	32942041	32942041	NUM
dpc-1303	139	4	.	.	PUNCT
dpc-1303	140	1	3	3	X
dpc-1303	140	2	.	.	X
dpc-1303	140	3	tavakolpour	tavakolpour	NUM
dpc-1303	140	4	s	s	NOUN
dpc-1303	140	5	,	,	PUNCT
dpc-1303	140	6	mahmoudi	mahmoudi	ADJ
dpc-1303	140	7	h	h	NOUN
dpc-1303	140	8	,	,	PUNCT
dpc-1303	140	9	mirzazadeh	mirzazadeh	PROPN
dpc-1303	140	10	a	a	PRON
dpc-1303	140	11	,	,	PUNCT
dpc-1303	140	12	et	et	PROPN
dpc-1303	140	13	al	al	PROPN
dpc-1303	140	14	.	.	PROPN
dpc-1303	140	15	pathogenic	pathogenic	ADJ
dpc-1303	140	16	and	and	CCONJ
dpc-1303	140	17	protective	protective	ADJ
dpc-1303	140	18	roles	role	NOUN
dpc-1303	140	19	of	of	ADP
dpc-1303	140	20	cytokines	cytokine	NOUN
dpc-1303	140	21	in	in	ADP
dpc-1303	140	22	pemphigus	pemphigus	NOUN
dpc-1303	140	23	:	:	PUNCT
dpc-1303	140	24	a	a	DET
dpc-1303	140	25	systematic	systematic	ADJ
dpc-1303	140	26	review	review	NOUN
dpc-1303	140	27	.	.	PUNCT
dpc-1303	141	1	cytokine	cytokine	NOUN
dpc-1303	141	2	.	.	PUNCT
dpc-1303	142	1	2020;129:155026	2020;129:155026	X
dpc-1303	142	2	.	.	PUNCT
dpc-1303	143	1	doi	doi	NOUN
dpc-1303	143	2	:	:	PUNCT
dpc-1303	143	3	10.1016	10.1016	NUM
dpc-1303	143	4	/	/	SYM
dpc-1303	143	5	j.cyto.2020.155026	j.cyto.2020.155026	PROPN
dpc-1303	143	6	.	.	PUNCT
dpc-1303	144	1	pmid	pmid	NOUN
dpc-1303	144	2	:	:	PUNCT
dpc-1303	144	3	32058276	32058276	NUM
dpc-1303	144	4	.	.	PUNCT
dpc-1303	145	1	4	4	X
dpc-1303	145	2	.	.	X
dpc-1303	145	3	mahmoudi	mahmoudi	PROPN
dpc-1303	145	4	h	h	PROPN
dpc-1303	145	5	,	,	PUNCT
dpc-1303	145	6	ebrahimi	ebrahimi	PROPN
dpc-1303	145	7	e	e	PROPN
dpc-1303	145	8	,	,	PUNCT
dpc-1303	145	9	daneshpazhooh	daneshpazhooh	VERB
dpc-1303	145	10	m	m	PROPN
dpc-1303	145	11	,	,	PUNCT
dpc-1303	145	12	et	et	PROPN
dpc-1303	145	13	al	al	PROPN
dpc-1303	145	14	.	.	PROPN
dpc-1303	145	15	single‐nucleotide	single‐nucleotide	PROPN
dpc-1303	145	16	polymorphisms	polymorphism	NOUN
dpc-1303	145	17	associated	associate	VERB
dpc-1303	145	18	with	with	ADP
dpc-1303	145	19	pemphigus	pemphigus	NOUN
dpc-1303	145	20	vulgaris	vulgaris	NOUN
dpc-1303	145	21	:	:	PUNCT
dpc-1303	145	22	potent	potent	ADJ
dpc-1303	145	23	markers	marker	NOUN
dpc-1303	145	24	for	for	ADP
dpc-1303	145	25	better	well	ADJ
dpc-1303	145	26	treatment	treatment	NOUN
dpc-1303	145	27	and	and	CCONJ
dpc-1303	145	28	personalized	personalized	ADJ
dpc-1303	145	29	medicine	medicine	NOUN
dpc-1303	145	30	.	.	PUNCT
dpc-1303	146	1	int	int	NOUN
dpc-1303	146	2	j	j	PROPN
dpc-1303	146	3	immunogenet	immunogenet	PROPN
dpc-1303	146	4	.	.	PUNCT
dpc-1303	147	1	2020;47(1):41	2020;47(1):41	NUM
dpc-1303	147	2	-	-	SYM
dpc-1303	147	3	49	49	NUM
dpc-1303	147	4	.	.	PUNCT
dpc-1303	148	1	doi	doi	NOUN
dpc-1303	148	2	:	:	PUNCT
dpc-1303	148	3	10.1111	10.1111	NUM
dpc-1303	148	4	/	/	SYM
dpc-1303	148	5	iji.12451	iji.12451	PROPN
dpc-1303	148	6	.	.	PUNCT
dpc-1303	149	1	pmid	pmid	NOUN
dpc-1303	149	2	:	:	PUNCT
dpc-1303	149	3	31342641	31342641	NUM
dpc-1303	149	4	.	.	PUNCT
dpc-1303	150	1	5	5	X
dpc-1303	150	2	.	.	X
dpc-1303	150	3	tavakolpour	tavakolpour	NUM
dpc-1303	150	4	s	s	PROPN
dpc-1303	150	5	,	,	PUNCT
dpc-1303	150	6	tavakolpour	tavakolpour	PRON
dpc-1303	150	7	v.	v.	ADP
dpc-1303	150	8	interleukin	interleukin	NOUN
dpc-1303	150	9	4	4	NUM
dpc-1303	150	10	inhibition	inhibition	NOUN
dpc-1303	150	11	as	as	ADP
dpc-1303	150	12	a	a	DET
dpc-1303	150	13	potential	potential	ADJ
dpc-1303	150	14	therapeutic	therapeutic	ADJ
dpc-1303	150	15	in	in	ADP
dpc-1303	150	16	pemphigus	pemphigus	PROPN
dpc-1303	150	17	.	.	PUNCT
dpc-1303	150	18	cytokine	cytokine	VERB
dpc-1303	150	19	.	.	PUNCT
dpc-1303	151	1	2016;77:1891	2016;77:1891	NUM
dpc-1303	151	2	-	-	SYM
dpc-1303	151	3	95	95	NUM
dpc-1303	151	4	.	.	PUNCT
dpc-1303	152	1	doi	doi	NOUN
dpc-1303	152	2	:	:	PUNCT
dpc-1303	152	3	10.1016	10.1016	NUM
dpc-1303	152	4	/	/	SYM
dpc-1303	152	5	j.cyto.2015.09.017	j.cyto.2015.09.017	X
dpc-1303	152	6	.	.	PUNCT
dpc-1303	153	1	pmid	pmid	NOUN
dpc-1303	153	2	:	:	PUNCT
dpc-1303	153	3	26440137	26440137	NUM
dpc-1303	153	4	.	.	PUNCT
dpc-1303	154	1	6	6	NUM
dpc-1303	154	2	.	.	X
dpc-1303	154	3	cho	cho	PROPN
dpc-1303	154	4	mj	mj	PROPN
dpc-1303	154	5	,	,	PUNCT
dpc-1303	154	6	ellebrecht	ellebrecht	PROPN
dpc-1303	154	7	ct	ct	PROPN
dpc-1303	154	8	,	,	PUNCT
dpc-1303	154	9	payne	payne	PROPN
dpc-1303	154	10	as	as	ADP
dpc-1303	154	11	.	.	PUNCT
dpc-1303	155	1	the	the	DET
dpc-1303	155	2	dual	dual	ADJ
dpc-1303	155	3	nature	nature	NOUN
dpc-1303	155	4	of	of	ADP
dpc-1303	155	5	interleukin-10	interleukin-10	PROPN
dpc-1303	155	6	in	in	ADP
dpc-1303	155	7	pemphigus	pemphigus	NOUN
dpc-1303	155	8	vulgaris	vulgaris	NOUN
dpc-1303	155	9	.	.	PUNCT
dpc-1303	156	1	cytokine	cytokine	NOUN
dpc-1303	156	2	.	.	PUNCT
dpc-1303	157	1	2015;73(2):335	2015;73(2):335	NUM
dpc-1303	157	2	-	-	SYM
dpc-1303	157	3	341	341	NUM
dpc-1303	157	4	.	.	PUNCT
dpc-1303	158	1	doi	doi	NOUN
dpc-1303	158	2	:	:	PUNCT
dpc-1303	158	3	10.1016	10.1016	NUM
dpc-1303	158	4	/	/	SYM
dpc-1303	158	5	j.cyto.2014.11.002	j.cyto.2014.11.002	NOUN
dpc-1303	158	6	.	.	PUNCT
dpc-1303	159	1	pmid	pmid	NOUN
dpc-1303	159	2	:	:	PUNCT
dpc-1303	159	3	25464924	25464924	NUM
dpc-1303	159	4	.	.	PUNCT
dpc-1303	160	1	7	7	X
dpc-1303	160	2	.	.	X
dpc-1303	160	3	tavakolpour	tavakolpour	NUM
dpc-1303	160	4	s.	s.	PROPN
dpc-1303	160	5	interleukin	interleukin	PROPN
dpc-1303	160	6	21	21	NUM
dpc-1303	160	7	as	as	ADP
dpc-1303	160	8	a	a	DET
dpc-1303	160	9	new	new	ADJ
dpc-1303	160	10	possible	possible	ADJ
dpc-1303	160	11	player	player	NOUN
dpc-1303	160	12	in	in	ADP
dpc-1303	160	13	pemphigus	pemphigus	PROPN
dpc-1303	160	14	:	:	PUNCT
dpc-1303	160	15	is	be	AUX
dpc-1303	160	16	it	it	PRON
dpc-1303	160	17	a	a	DET
dpc-1303	160	18	suitable	suitable	ADJ
dpc-1303	160	19	target	target	NOUN
dpc-1303	160	20	?	?	PUNCT
dpc-1303	161	1	int	int	NOUN
dpc-1303	161	2	immunopharmacol	immunopharmacol	PROPN
dpc-1303	161	3	.	.	PUNCT
dpc-1303	162	1	2016;34:139145	2016;34:139145	X
dpc-1303	162	2	.	.	PUNCT
dpc-1303	162	3	doi	doi	NOUN
dpc-1303	162	4	:	:	PUNCT
dpc-1303	162	5	10.1016	10.1016	NUM
dpc-1303	162	6	/	/	SYM
dpc-1303	162	7	j.intimp.2016.02.020	j.intimp.2016.02.020	PROPN
dpc-1303	162	8	.	.	PUNCT
dpc-1303	163	1	pmid	pmid	NOUN
dpc-1303	163	2	:	:	PUNCT
dpc-1303	163	3	26945832	26945832	NUM
dpc-1303	163	4	.	.	X
dpc-1303	164	1	8	8	X
dpc-1303	164	2	.	.	X
dpc-1303	165	1	tavakolpour	tavakolpour	NUM
dpc-1303	165	2	s	s	PROPN
dpc-1303	165	3	,	,	PUNCT
dpc-1303	165	4	kheiry	kheiry	PROPN
dpc-1303	165	5	f	f	PROPN
dpc-1303	165	6	,	,	PUNCT
dpc-1303	165	7	mirsafaei	mirsafaei	ADJ
dpc-1303	165	8	hs	hs	PROPN
dpc-1303	165	9	,	,	PUNCT
dpc-1303	165	10	akhlaghdoust	akhlaghdoust	PROPN
dpc-1303	165	11	m.	m.	NOUN
dpc-1303	165	12	the	the	DET
dpc-1303	165	13	possible	possible	ADJ
dpc-1303	165	14	role	role	NOUN
dpc-1303	165	15	of	of	ADP
dpc-1303	165	16	interleukin-35	interleukin-35	PROPN
dpc-1303	165	17	and	and	CCONJ
dpc-1303	165	18	its	its	PRON
dpc-1303	165	19	therapeutic	therapeutic	ADJ
dpc-1303	165	20	potential	potential	NOUN
dpc-1303	165	21	in	in	ADP
dpc-1303	165	22	pemphigus	pemphigus	PROPN
dpc-1303	165	23	.	.	PUNCT
dpc-1303	166	1	int	int	PROPN
dpc-1303	166	2	immunopharmacol	immunopharmacol	PROPN
dpc-1303	166	3	.	.	PUNCT
dpc-1303	167	1	2017;42:11	2017;42:11	NUM
dpc-1303	167	2	-	-	SYM
dpc-1303	167	3	7	7	NUM
dpc-1303	167	4	.	.	PUNCT
dpc-1303	167	5	doi	doi	NOUN
dpc-1303	167	6	:	:	PUNCT
dpc-1303	167	7	10.1016	10.1016	NUM
dpc-1303	167	8	/	/	SYM
dpc-1303	167	9	j.intimp.2016.11.005	j.intimp.2016.11.005	PROPN
dpc-1303	167	10	.	.	PUNCT
dpc-1303	168	1	pmid	pmid	NOUN
dpc-1303	168	2	:	:	PUNCT
dpc-1303	168	3	27855302	27855302	NUM
dpc-1303	168	4	.	.	PUNCT
dpc-1303	169	1	9	9	X
dpc-1303	169	2	.	.	PUNCT
dpc-1303	170	1	takahashi	takahashi	PROPN
dpc-1303	170	2	h	h	PROPN
dpc-1303	170	3	,	,	PUNCT
dpc-1303	170	4	kouno	kouno	PROPN
dpc-1303	170	5	m	m	PROPN
dpc-1303	170	6	,	,	PUNCT
dpc-1303	170	7	nagao	nagao	ADJ
dpc-1303	170	8	k	k	PROPN
dpc-1303	170	9	,	,	PUNCT
dpc-1303	170	10	et	et	PROPN
dpc-1303	170	11	al	al	PROPN
dpc-1303	170	12	.	.	PROPN
dpc-1303	170	13	desmoglein	desmoglein	PROPN
dpc-1303	170	14	3	3	NUM
dpc-1303	170	15	-	-	PUNCT
dpc-1303	170	16	specific	specific	ADJ
dpc-1303	170	17	cd4	cd4	PROPN
dpc-1303	170	18	+	+	PROPN
dpc-1303	170	19	t	t	NOUN
dpc-1303	170	20	cells	cell	NOUN
dpc-1303	170	21	induce	induce	VERB
dpc-1303	170	22	pemphigus	pemphigus	ADJ
dpc-1303	170	23	vulgaris	vulgaris	NOUN
dpc-1303	170	24	and	and	CCONJ
dpc-1303	170	25	interface	interface	NOUN
dpc-1303	170	26	dermatitis	dermatitis	NOUN
dpc-1303	170	27	6	6	NUM
dpc-1303	170	28	research	research	NOUN
dpc-1303	171	1	|	|	ADV
dpc-1303	171	2	dermatol	dermatol	ADJ
dpc-1303	171	3	pract	pract	NOUN
dpc-1303	171	4	concept	concept	NOUN
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dpc-1303	171	6	in	in	ADP
dpc-1303	171	7	mice	mouse	NOUN
dpc-1303	171	8	.	.	PUNCT
dpc-1303	172	1	j	j	PROPN
dpc-1303	172	2	clin	clin	PROPN
dpc-1303	172	3	invest	invest	PROPN
dpc-1303	172	4	.	.	PUNCT
dpc-1303	173	1	2011;121(9):3677	2011;121(9):3677	NUM
dpc-1303	173	2	-	-	SYM
dpc-1303	173	3	3688	3688	NUM
dpc-1303	173	4	.	.	PUNCT
dpc-1303	174	1	doi	doi	NOUN
dpc-1303	174	2	:	:	PUNCT
dpc-1303	174	3	10.1172/	10.1172/	NUM
dpc-1303	174	4	jci57379	jci57379	NOUN
dpc-1303	174	5	.	.	PUNCT
dpc-1303	175	1	pmid	pmid	NOUN
dpc-1303	175	2	:	:	PUNCT
dpc-1303	175	3	21821914	21821914	NUM
dpc-1303	175	4	.	.	PUNCT
dpc-1303	176	1	10	10	NUM
dpc-1303	176	2	.	.	PUNCT
dpc-1303	177	1	veldman	veldman	NOUN
dpc-1303	177	2	cm	cm	PROPN
dpc-1303	177	3	,	,	PUNCT
dpc-1303	177	4	gebhard	gebhard	NOUN
dpc-1303	177	5	kl	kl	NOUN
dpc-1303	177	6	,	,	PUNCT
dpc-1303	177	7	uter	uter	PROPN
dpc-1303	177	8	w	w	PROPN
dpc-1303	177	9	,	,	PUNCT
dpc-1303	177	10	et	et	PROPN
dpc-1303	177	11	al	al	PROPN
dpc-1303	177	12	.	.	PROPN
dpc-1303	177	13	t	t	PROPN
dpc-1303	177	14	cell	cell	NOUN
dpc-1303	177	15	recognition	recognition	NOUN
dpc-1303	177	16	of	of	ADP
dpc-1303	177	17	desmoglein	desmoglein	ADJ
dpc-1303	177	18	3	3	NUM
dpc-1303	177	19	peptides	peptide	NOUN
dpc-1303	177	20	in	in	ADP
dpc-1303	177	21	patients	patient	NOUN
dpc-1303	177	22	with	with	ADP
dpc-1303	177	23	pemphigus	pemphigus	NOUN
dpc-1303	177	24	vulgaris	vulgaris	NOUN
dpc-1303	177	25	and	and	CCONJ
dpc-1303	177	26	healthy	healthy	ADJ
dpc-1303	177	27	individuals	individual	NOUN
dpc-1303	177	28	.	.	PUNCT
dpc-1303	178	1	j	j	PROPN
dpc-1303	178	2	immunol	immunol	NOUN
dpc-1303	178	3	.	.	PUNCT
dpc-1303	179	1	2004;172(6):3883	2004;172(6):3883	NUM
dpc-1303	179	2	.	.	PUNCT
dpc-1303	179	3	doi	doi	NOUN
dpc-1303	179	4	:	:	PUNCT
dpc-1303	179	5	10.4049	10.4049	NUM
dpc-1303	179	6	/	/	SYM
dpc-1303	179	7	jimmunol.172.6.3883	jimmunol.172.6.3883	NOUN
dpc-1303	179	8	.	.	PUNCT
dpc-1303	180	1	pmid	pmid	NOUN
dpc-1303	180	2	:	:	PUNCT
dpc-1303	180	3	15004196	15004196	NUM
dpc-1303	180	4	.	.	PUNCT
dpc-1303	181	1	11	11	NUM
dpc-1303	181	2	.	.	PUNCT
dpc-1303	181	3	hennerici	hennerici	PROPN
dpc-1303	181	4	t	t	PROPN
dpc-1303	181	5	,	,	PUNCT
dpc-1303	181	6	pollmann	pollmann	ADJ
dpc-1303	181	7	r	r	NOUN
dpc-1303	181	8	,	,	PUNCT
dpc-1303	181	9	schmidt	schmidt	PROPN
dpc-1303	181	10	t	t	PROPN
dpc-1303	181	11	,	,	PUNCT
dpc-1303	181	12	et	et	PROPN
dpc-1303	182	1	al	al	PROPN
dpc-1303	182	2	.	.	PROPN
dpc-1303	182	3	increased	increase	VERB
dpc-1303	182	4	frequency	frequency	NOUN
dpc-1303	182	5	of	of	ADP
dpc-1303	182	6	t	t	PROPN
dpc-1303	182	7	follicular	follicular	ADJ
dpc-1303	182	8	helper	helper	NOUN
dpc-1303	182	9	cells	cell	NOUN
dpc-1303	182	10	and	and	CCONJ
dpc-1303	182	11	elevated	elevate	VERB
dpc-1303	182	12	interleukin-27	interleukin-27	PROPN
dpc-1303	182	13	plasma	plasma	NOUN
dpc-1303	182	14	levels	level	NOUN
dpc-1303	182	15	in	in	ADP
dpc-1303	182	16	patients	patient	NOUN
dpc-1303	182	17	with	with	ADP
dpc-1303	182	18	pemphigus	pemphigus	PROPN
dpc-1303	182	19	.	.	PUNCT
dpc-1303	183	1	plos	plos	PROPN
dpc-1303	183	2	one	one	NUM
dpc-1303	183	3	.	.	PUNCT
dpc-1303	184	1	2016;11(2):e0148919	2016;11(2):e0148919	X
dpc-1303	184	2	.	.	PUNCT
dpc-1303	184	3	doi	doi	NOUN
dpc-1303	184	4	:	:	PUNCT
dpc-1303	184	5	10.1371	10.1371	NUM
dpc-1303	184	6	/	/	SYM
dpc-1303	184	7	journal.pone.0148919	journal.pone.0148919	PROPN
dpc-1303	184	8	.	.	PUNCT
dpc-1303	185	1	pmid	pmid	NOUN
dpc-1303	185	2	:	:	PUNCT
dpc-1303	185	3	26872212	26872212	NUM
dpc-1303	185	4	.	.	PUNCT
dpc-1303	186	1	12	12	NUM
dpc-1303	186	2	.	.	PUNCT
dpc-1303	187	1	zhu	zhu	PROPN
dpc-1303	187	2	h	h	PROPN
dpc-1303	187	3	,	,	PUNCT
dpc-1303	187	4	chen	chen	PROPN
dpc-1303	187	5	y	y	PROPN
dpc-1303	187	6	,	,	PUNCT
dpc-1303	187	7	zhou	zhou	PROPN
dpc-1303	187	8	y	y	PROPN
dpc-1303	187	9	,	,	PUNCT
dpc-1303	187	10	wang	wang	PROPN
dpc-1303	187	11	y	y	PROPN
dpc-1303	187	12	,	,	PUNCT
dpc-1303	187	13	zheng	zheng	PROPN
dpc-1303	187	14	j	j	PROPN
dpc-1303	187	15	,	,	PUNCT
dpc-1303	187	16	pan	pan	PROPN
dpc-1303	187	17	m.	m.	PROPN
dpc-1303	187	18	cognate	cognate	PROPN
dpc-1303	187	19	th2	th2	PROPN
dpc-1303	187	20	-	-	PUNCT
dpc-1303	187	21	b	b	PROPN
dpc-1303	187	22	cell	cell	NOUN
dpc-1303	187	23	interaction	interaction	NOUN
dpc-1303	187	24	is	be	AUX
dpc-1303	187	25	essential	essential	ADJ
dpc-1303	187	26	for	for	ADP
dpc-1303	187	27	the	the	DET
dpc-1303	187	28	autoantibody	autoantibody	ADJ
dpc-1303	187	29	production	production	NOUN
dpc-1303	187	30	in	in	ADP
dpc-1303	187	31	pemphigus	pemphigus	PROPN
dpc-1303	187	32	vulgaris	vulgaris	NOUN
dpc-1303	187	33	.	.	PUNCT
dpc-1303	188	1	j	j	PROPN
dpc-1303	188	2	clin	clin	PROPN
dpc-1303	188	3	immunol	immunol	NOUN
dpc-1303	188	4	.	.	PUNCT
dpc-1303	189	1	2012;32(1):114	2012;32(1):114	NUM
dpc-1303	189	2	-	-	SYM
dpc-1303	189	3	123	123	NUM
dpc-1303	189	4	.	.	PUNCT
dpc-1303	190	1	doi	doi	NOUN
dpc-1303	190	2	:	:	PUNCT
dpc-1303	190	3	10.1007	10.1007	NUM
dpc-1303	190	4	/	/	SYM
dpc-1303	190	5	s10875	s10875	NOUN
dpc-1303	190	6	-	-	PUNCT
dpc-1303	190	7	011	011	NUM
dpc-1303	190	8	-	-	PUNCT
dpc-1303	190	9	9597	9597	NUM
dpc-1303	190	10	-	-	PUNCT
dpc-1303	190	11	4	4	NUM
dpc-1303	190	12	.	.	PUNCT
dpc-1303	191	1	pmid	pmid	NOUN
dpc-1303	191	2	:	:	PUNCT
dpc-1303	191	3	22009001	22009001	NUM
dpc-1303	191	4	.	.	PUNCT
dpc-1303	192	1	13	13	NUM
dpc-1303	192	2	.	.	PUNCT
dpc-1303	193	1	xu	xu	PROPN
dpc-1303	194	1	rc	rc	PROPN
dpc-1303	194	2	,	,	PUNCT
dpc-1303	194	3	zhu	zhu	PROPN
dpc-1303	194	4	hq	hq	PROPN
dpc-1303	194	5	,	,	PUNCT
dpc-1303	194	6	li	li	PROPN
dpc-1303	194	7	wp	wp	PROPN
dpc-1303	194	8	,	,	PUNCT
dpc-1303	194	9	zhao	zhao	PROPN
dpc-1303	194	10	xq	xq	PROPN
dpc-1303	194	11	,	,	PUNCT
dpc-1303	194	12	yuan	yuan	PROPN
dpc-1303	194	13	hj	hj	PROPN
dpc-1303	194	14	,	,	PUNCT
dpc-1303	194	15	zheng	zheng	PROPN
dpc-1303	194	16	j	j	PROPN
dpc-1303	194	17	,	,	PUNCT
dpc-1303	194	18	et	et	PROPN
dpc-1303	194	19	al	al	PROPN
dpc-1303	194	20	.	.	PUNCT
dpc-1303	195	1	the	the	DET
dpc-1303	195	2	imbalance	imbalance	NOUN
dpc-1303	195	3	of	of	ADP
dpc-1303	195	4	th17	th17	PROPN
dpc-1303	195	5	and	and	CCONJ
dpc-1303	195	6	regulatory	regulatory	ADJ
dpc-1303	195	7	t	t	NOUN
dpc-1303	195	8	cells	cell	NOUN
dpc-1303	195	9	in	in	ADP
dpc-1303	195	10	pemphigus	pemphigus	NOUN
dpc-1303	195	11	patients	patient	NOUN
dpc-1303	195	12	.	.	PUNCT
dpc-1303	196	1	eur	eur	PROPN
dpc-1303	196	2	j	j	PROPN
dpc-1303	196	3	dermatol	dermatol	NOUN
dpc-1303	196	4	.	.	PUNCT
dpc-1303	197	1	2013;23(6):795	2013;23(6):795	NUM
dpc-1303	197	2	-	-	SYM
dpc-1303	197	3	802	802	NUM
dpc-1303	197	4	.	.	PUNCT
dpc-1303	198	1	doi	doi	NOUN
dpc-1303	198	2	:	:	PUNCT
dpc-1303	198	3	10.1684/	10.1684/	NUM
dpc-1303	198	4	ejd.2013.2177	ejd.2013.2177	NUM
dpc-1303	198	5	.	.	PUNCT
dpc-1303	199	1	pmid	pmid	NOUN
dpc-1303	199	2	:	:	PUNCT
dpc-1303	199	3	24192290	24192290	NUM
dpc-1303	199	4	.	.	PUNCT
dpc-1303	200	1	14	14	NUM
dpc-1303	200	2	.	.	PUNCT
dpc-1303	201	1	kim	kim	PROPN
dpc-1303	201	2	ar	ar	PROPN
dpc-1303	201	3	,	,	PUNCT
dpc-1303	201	4	han	han	PROPN
dpc-1303	201	5	d	d	PROPN
dpc-1303	201	6	,	,	PUNCT
dpc-1303	201	7	choi	choi	PROPN
dpc-1303	201	8	jy	jy	PROPN
dpc-1303	201	9	,	,	PUNCT
dpc-1303	201	10	seok	seok	PROPN
dpc-1303	201	11	j	j	PROPN
dpc-1303	201	12	,	,	PUNCT
dpc-1303	201	13	kim	kim	PROPN
dpc-1303	201	14	s	s	PROPN
dpc-1303	201	15	-	-	PUNCT
dpc-1303	201	16	e	e	NOUN
dpc-1303	201	17	,	,	PUNCT
dpc-1303	201	18	seo	seo	PROPN
dpc-1303	201	19	s	s	PROPN
dpc-1303	201	20	-	-	PUNCT
dpc-1303	201	21	h	h	NOUN
dpc-1303	201	22	,	,	PUNCT
dpc-1303	201	23	et	et	PROPN
dpc-1303	201	24	al	al	PROPN
dpc-1303	201	25	.	.	PUNCT
dpc-1303	202	1	targeting	target	VERB
dpc-1303	202	2	icos	icos	PROPN
dpc-1303	202	3	expressed	express	VERB
dpc-1303	202	4	on	on	ADP
dpc-1303	202	5	cxcr5	cxcr5	PROPN
dpc-1303	202	6	+	+	SYM
dpc-1303	202	7	pd-1	pd-1	NOUN
dpc-1303	202	8	+	+	NOUN
dpc-1303	202	9	t	t	NOUN
dpc-1303	202	10	helper	helper	NOUN
dpc-1303	202	11	cells	cell	NOUN
dpc-1303	202	12	suppresses	suppress	VERB
dpc-1303	202	13	the	the	DET
dpc-1303	202	14	progression	progression	NOUN
dpc-1303	202	15	of	of	ADP
dpc-1303	202	16	pemphigus	pemphigus	PROPN
dpc-1303	202	17	vulgaris	vulgaris	NOUN
dpc-1303	202	18	.	.	PUNCT
dpc-1303	203	1	j	j	PROPN
dpc-1303	203	2	allergy	allergy	PROPN
dpc-1303	203	3	clin	clin	PROPN
dpc-1303	203	4	immunol	immunol	NOUN
dpc-1303	203	5	.	.	PUNCT
dpc-1303	204	1	2020;146(5):1070	2020;146(5):1070	NUM
dpc-1303	204	2	-	-	SYM
dpc-1303	204	3	1079.e8	1079.e8	PROPN
dpc-1303	204	4	.	.	PUNCT
dpc-1303	204	5	doi	doi	NOUN
dpc-1303	204	6	:	:	PUNCT
dpc-1303	204	7	10.1016	10.1016	NUM
dpc-1303	204	8	/	/	SYM
dpc-1303	204	9	j.jaci.2020.03.036	j.jaci.2020.03.036	PROPN
dpc-1303	204	10	.	.	PUNCT
dpc-1303	205	1	pmid	pmid	NOUN
dpc-1303	205	2	:	:	PUNCT
dpc-1303	205	3	32311391	32311391	NUM
dpc-1303	205	4	.	.	PUNCT
dpc-1303	206	1	15	15	NUM
dpc-1303	206	2	.	.	PUNCT
dpc-1303	207	1	tavakolpour	tavakolpour	NUM
dpc-1303	207	2	s	s	PROPN
dpc-1303	207	3	,	,	PUNCT
dpc-1303	207	4	tavakolpour	tavakolpour	PRON
dpc-1303	207	5	v.	v.	ADP
dpc-1303	207	6	interleukin	interleukin	NOUN
dpc-1303	207	7	4	4	NUM
dpc-1303	207	8	inhibition	inhibition	NOUN
dpc-1303	207	9	as	as	ADP
dpc-1303	207	10	a	a	DET
dpc-1303	207	11	potential	potential	ADJ
dpc-1303	207	12	therapeutic	therapeutic	ADJ
dpc-1303	207	13	in	in	ADP
dpc-1303	207	14	pemphigus	pemphigus	PROPN
dpc-1303	207	15	.	.	PUNCT
dpc-1303	208	1	cytokine	cytokine	VERB
dpc-1303	208	2	.	.	PUNCT
dpc-1303	209	1	2016;77:189	2016;77:189	PROPN
dpc-1303	209	2	-	-	SYM
dpc-1303	209	3	95	95	NUM
dpc-1303	209	4	.	.	PUNCT
dpc-1303	210	1	doi	doi	NOUN
dpc-1303	210	2	:	:	PUNCT
dpc-1303	210	3	10.1016	10.1016	NUM
dpc-1303	210	4	/	/	SYM
dpc-1303	210	5	j.cyto.2015.09.017	j.cyto.2015.09.017	X
dpc-1303	210	6	.	.	PUNCT
dpc-1303	211	1	pmid	pmid	NOUN
dpc-1303	211	2	:	:	PUNCT
dpc-1303	211	3	26440137	26440137	NUM
dpc-1303	211	4	.	.	PUNCT
dpc-1303	212	1	16	16	NUM
dpc-1303	212	2	.	.	PUNCT
dpc-1303	213	1	murrell	murrell	PROPN
dpc-1303	213	2	df	df	PROPN
dpc-1303	213	3	,	,	PUNCT
dpc-1303	213	4	dick	dick	PROPN
dpc-1303	213	5	s	s	PROPN
dpc-1303	213	6	,	,	PUNCT
dpc-1303	213	7	ahmed	ahme	VERB
dpc-1303	213	8	a	a	PROPN
dpc-1303	213	9	,	,	PUNCT
dpc-1303	213	10	et	et	PROPN
dpc-1303	213	11	al	al	PROPN
dpc-1303	213	12	.	.	PUNCT
dpc-1303	214	1	consensus	consensus	NOUN
dpc-1303	214	2	statement	statement	NOUN
dpc-1303	214	3	on	on	ADP
dpc-1303	214	4	definitions	definition	NOUN
dpc-1303	214	5	of	of	ADP
dpc-1303	214	6	disease	disease	NOUN
dpc-1303	214	7	,	,	PUNCT
dpc-1303	214	8	end	end	NOUN
dpc-1303	214	9	points	point	NOUN
dpc-1303	214	10	,	,	PUNCT
dpc-1303	214	11	and	and	CCONJ
dpc-1303	214	12	therapeutic	therapeutic	ADJ
dpc-1303	214	13	response	response	NOUN
dpc-1303	214	14	for	for	ADP
dpc-1303	214	15	pemphigus	pemphigus	PROPN
dpc-1303	214	16	.	.	PUNCT
dpc-1303	215	1	j	j	PROPN
dpc-1303	215	2	am	be	AUX
dpc-1303	215	3	acad	acad	ADJ
dpc-1303	215	4	dermatol	dermatol	NOUN
dpc-1303	215	5	.	.	PUNCT
dpc-1303	216	1	2008;58(6):1043	2008;58(6):1043	NUM
dpc-1303	216	2	-	-	SYM
dpc-1303	216	3	1046	1046	NUM
dpc-1303	216	4	.	.	PUNCT
dpc-1303	217	1	doi	doi	NOUN
dpc-1303	217	2	:	:	PUNCT
dpc-1303	217	3	10.1016	10.1016	NUM
dpc-1303	217	4	/	/	SYM
dpc-1303	217	5	j.jaad.2008.01.012	j.jaad.2008.01.012	PROPN
dpc-1303	217	6	.	.	PUNCT
dpc-1303	218	1	pmid	pmid	PROPN
dpc-1303	218	2	:	:	PUNCT
dpc-1303	218	3	18339444	18339444	NUM
dpc-1303	218	4	.	.	PUNCT
dpc-1303	219	1	17	17	NUM
dpc-1303	219	2	.	.	X
dpc-1303	219	3	satyam	satyam	PROPN
dpc-1303	219	4	a	a	PRON
dpc-1303	219	5	,	,	PUNCT
dpc-1303	219	6	khandpur	khandpur	NOUN
dpc-1303	219	7	s	s	X
dpc-1303	219	8	,	,	PUNCT
dpc-1303	219	9	sharma	sharma	PROPN
dpc-1303	219	10	vk	vk	PROPN
dpc-1303	219	11	,	,	PUNCT
dpc-1303	219	12	sharma	sharma	PROPN
dpc-1303	219	13	a.	a.	NOUN
dpc-1303	219	14	involvement	involvement	NOUN
dpc-1303	219	15	of	of	ADP
dpc-1303	219	16	t(h)1	t(h)1	PROPN
dpc-1303	219	17	/	/	SYM
dpc-1303	219	18	t(h)2	t(h)2	PROPN
dpc-1303	219	19	cytokines	cytokine	VERB
dpc-1303	219	20	in	in	ADP
dpc-1303	219	21	the	the	DET
dpc-1303	219	22	pathogenesis	pathogenesis	NOUN
dpc-1303	219	23	of	of	ADP
dpc-1303	219	24	autoimmune	autoimmune	ADJ
dpc-1303	219	25	skin	skin	NOUN
dpc-1303	219	26	disease	disease	NOUN
dpc-1303	219	27	-	-	PUNCT
dpc-1303	219	28	pemphigus	pemphigus	ADJ
dpc-1303	219	29	vulgaris	vulgaris	NOUN
dpc-1303	219	30	.	.	PUNCT
dpc-1303	220	1	immunol	immunol	NOUN
dpc-1303	220	2	invest	invest	PROPN
dpc-1303	220	3	.	.	PUNCT
dpc-1303	221	1	2009;38(6):498509	2009;38(6):498509	NUM
dpc-1303	221	2	.	.	PUNCT
dpc-1303	222	1	doi	doi	NOUN
dpc-1303	222	2	:	:	PUNCT
dpc-1303	222	3	10.1080/08820130902943097	10.1080/08820130902943097	NUM
dpc-1303	222	4	.	.	PUNCT
dpc-1303	223	1	pmid	pmid	NOUN
dpc-1303	223	2	:	:	PUNCT
dpc-1303	223	3	19811408	19811408	NUM
dpc-1303	223	4	.	.	PUNCT
dpc-1303	224	1	18	18	NUM
dpc-1303	224	2	.	.	X
dpc-1303	225	1	el	el	PROPN
dpc-1303	225	2	-	-	PUNCT
dpc-1303	225	3	darouti	darouti	PROPN
dpc-1303	225	4	ma	ma	PROPN
dpc-1303	225	5	,	,	PUNCT
dpc-1303	225	6	hegazy	hegazy	PROPN
dpc-1303	225	7	ra	ra	PROPN
dpc-1303	225	8	,	,	PUNCT
dpc-1303	225	9	abdel	abdel	PROPN
dpc-1303	225	10	hay	hay	PROPN
dpc-1303	225	11	rm	rm	PROPN
dpc-1303	225	12	,	,	PUNCT
dpc-1303	225	13	et	et	PROPN
dpc-1303	225	14	al	al	PROPN
dpc-1303	225	15	.	.	PROPN
dpc-1303	225	16	study	study	PROPN
dpc-1303	225	17	of	of	ADP
dpc-1303	225	18	t	t	PROPN
dpc-1303	225	19	helper	helper	NOUN
dpc-1303	225	20	1	1	NUM
dpc-1303	225	21	and	and	CCONJ
dpc-1303	225	22	t	t	PROPN
dpc-1303	225	23	helper	helper	NOUN
dpc-1303	225	24	2	2	NUM
dpc-1303	225	25	responses	response	NOUN
dpc-1303	225	26	in	in	ADP
dpc-1303	225	27	pemphigus	pemphigus	ADJ
dpc-1303	225	28	vulgaris	vulgaris	NOUN
dpc-1303	225	29	patients	patient	NOUN
dpc-1303	225	30	receiving	receive	VERB
dpc-1303	225	31	interferon	interferon	ADJ
dpc-1303	225	32	alpha	alpha	NOUN
dpc-1303	225	33	2a	2a	NUM
dpc-1303	225	34	injections	injection	NOUN
dpc-1303	225	35	in	in	ADP
dpc-1303	225	36	addition	addition	NOUN
dpc-1303	225	37	to	to	ADP
dpc-1303	225	38	a	a	DET
dpc-1303	225	39	standard	standard	ADJ
dpc-1303	225	40	protocol	protocol	NOUN
dpc-1303	225	41	therapy	therapy	NOUN
dpc-1303	225	42	:	:	PUNCT
dpc-1303	225	43	a	a	DET
dpc-1303	225	44	randomized	randomized	ADJ
dpc-1303	225	45	controlled	control	VERB
dpc-1303	225	46	trial	trial	NOUN
dpc-1303	225	47	.	.	PUNCT
dpc-1303	226	1	arch	arch	ADJ
dpc-1303	226	2	dermatol	dermatol	NOUN
dpc-1303	226	3	res	re	NOUN
dpc-1303	226	4	.	.	PUNCT
dpc-1303	227	1	2015;307(4):299	2015;307(4):299	NUM
dpc-1303	227	2	-	-	SYM
dpc-1303	227	3	307	307	NUM
dpc-1303	227	4	.	.	PUNCT
dpc-1303	228	1	doi	doi	NOUN
dpc-1303	228	2	:	:	PUNCT
dpc-1303	228	3	10.1007	10.1007	NUM
dpc-1303	228	4	/	/	SYM
dpc-1303	228	5	s00403	s00403	NOUN
dpc-1303	228	6	-	-	PUNCT
dpc-1303	228	7	014	014	NUM
dpc-1303	228	8	-	-	PUNCT
dpc-1303	228	9	1522	1522	NUM
dpc-1303	228	10	-	-	SYM
dpc-1303	228	11	2	2	NUM
dpc-1303	228	12	.	.	PUNCT
dpc-1303	229	1	pmid	pmid	NOUN
dpc-1303	229	2	:	:	PUNCT
dpc-1303	229	3	25450635	25450635	NUM
dpc-1303	229	4	.	.	PUNCT
dpc-1303	230	1	19	19	NUM
dpc-1303	230	2	.	.	PUNCT
dpc-1303	231	1	lee	lee	PROPN
dpc-1303	231	2	sh	sh	PROPN
dpc-1303	231	3	,	,	PUNCT
dpc-1303	231	4	hong	hong	PROPN
dpc-1303	231	5	wj	wj	PROPN
dpc-1303	231	6	,	,	PUNCT
dpc-1303	231	7	kim	kim	PROPN
dpc-1303	231	8	s	s	PROPN
dpc-1303	231	9	-	-	PROPN
dpc-1303	231	10	c.	c.	NOUN
dpc-1303	231	11	analysis	analysis	NOUN
dpc-1303	231	12	of	of	ADP
dpc-1303	231	13	serum	serum	NOUN
dpc-1303	231	14	cytokine	cytokine	NOUN
dpc-1303	231	15	profile	profile	NOUN
dpc-1303	231	16	in	in	ADP
dpc-1303	231	17	pemphigus	pemphigus	PROPN
dpc-1303	231	18	.	.	PUNCT
dpc-1303	232	1	ann	ann	PROPN
dpc-1303	232	2	dermatol	dermatol	NOUN
dpc-1303	232	3	.	.	PUNCT
dpc-1303	233	1	2017;29(4):438	2017;29(4):438	NUM
dpc-1303	233	2	-	-	SYM
dpc-1303	233	3	445	445	NUM
dpc-1303	233	4	.	.	PUNCT
dpc-1303	234	1	doi	doi	NOUN
dpc-1303	234	2	:	:	PUNCT
dpc-1303	234	3	10.5021/	10.5021/	NUM
dpc-1303	234	4	ad.2017.29.4.438	ad.2017.29.4.438	NOUN
dpc-1303	234	5	.	.	PUNCT
dpc-1303	235	1	pmid	pmid	NOUN
dpc-1303	235	2	:	:	PUNCT
dpc-1303	235	3	28761292	28761292	NUM
dpc-1303	235	4	.	.	PUNCT
dpc-1303	236	1	20	20	NUM
dpc-1303	236	2	.	.	PUNCT
dpc-1303	236	3	timoteo	timoteo	PROPN
dpc-1303	236	4	rp	rp	PROPN
dpc-1303	236	5	,	,	PUNCT
dpc-1303	236	6	da	da	PROPN
dpc-1303	236	7	silva	silva	PROPN
dpc-1303	236	8	mv	mv	PROPN
dpc-1303	236	9	,	,	PUNCT
dpc-1303	236	10	miguel	miguel	PROPN
dpc-1303	236	11	cb	cb	PROPN
dpc-1303	236	12	,	,	PUNCT
dpc-1303	236	13	et	et	PROPN
dpc-1303	236	14	al	al	PROPN
dpc-1303	236	15	.	.	PUNCT
dpc-1303	237	1	th1	th1	PROPN
dpc-1303	237	2	/	/	SYM
dpc-1303	237	3	th17	th17	PROPN
dpc-1303	237	4	-	-	PUNCT
dpc-1303	237	5	related	relate	VERB
dpc-1303	237	6	cytokines	cytokine	NOUN
dpc-1303	237	7	and	and	CCONJ
dpc-1303	237	8	chemokines	chemokine	NOUN
dpc-1303	237	9	and	and	CCONJ
dpc-1303	237	10	their	their	PRON
dpc-1303	237	11	implications	implication	NOUN
dpc-1303	237	12	in	in	ADP
dpc-1303	237	13	the	the	DET
dpc-1303	237	14	pathogenesis	pathogenesis	NOUN
dpc-1303	237	15	of	of	ADP
dpc-1303	237	16	pemphigus	pemphigus	NOUN
dpc-1303	237	17	vulgaris	vulgaris	NOUN
dpc-1303	237	18	.	.	PUNCT
dpc-1303	238	1	mediators	mediator	NOUN
dpc-1303	238	2	inflamm	inflamm	NOUN
dpc-1303	238	3	.	.	PUNCT
dpc-1303	239	1	2017;2017:7151285	2017;2017:7151285	NUM
dpc-1303	239	2	.	.	PUNCT
dpc-1303	240	1	doi	doi	NOUN
dpc-1303	240	2	:	:	PUNCT
dpc-1303	240	3	10.1155/2017/7151285	10.1155/2017/7151285	NUM
dpc-1303	240	4	.	.	PUNCT
dpc-1303	241	1	pmid	pmid	NOUN
dpc-1303	241	2	:	:	PUNCT
dpc-1303	241	3	28321152	28321152	NUM
dpc-1303	241	4	.	.	PUNCT
dpc-1303	242	1	21	21	NUM
dpc-1303	242	2	.	.	PUNCT
dpc-1303	243	1	tavakolpour	tavakolpour	NUM
dpc-1303	243	2	s.	s.	PROPN
dpc-1303	243	3	dupilumab	dupilumab	PROPN
dpc-1303	243	4	:	:	PUNCT
dpc-1303	243	5	a	a	DET
dpc-1303	243	6	revolutionary	revolutionary	ADJ
dpc-1303	243	7	emerging	emerge	VERB
dpc-1303	243	8	drug	drug	NOUN
dpc-1303	243	9	in	in	ADP
dpc-1303	243	10	atopic	atopic	NOUN
dpc-1303	243	11	dermatitis	dermatitis	NOUN
dpc-1303	243	12	and	and	CCONJ
dpc-1303	243	13	its	its	PRON
dpc-1303	243	14	possible	possible	ADJ
dpc-1303	243	15	role	role	NOUN
dpc-1303	243	16	in	in	ADP
dpc-1303	243	17	pemphigus	pemphigus	PROPN
dpc-1303	243	18	.	.	PUNCT
dpc-1303	244	1	dermatol	dermatol	NOUN
dpc-1303	244	2	ther	ther	ADV
dpc-1303	244	3	.	.	PUNCT
dpc-1303	245	1	2016;29(5):299	2016;29(5):299	NUM
dpc-1303	245	2	.	.	PUNCT
dpc-1303	246	1	doi	doi	NOUN
dpc-1303	246	2	:	:	PUNCT
dpc-1303	246	3	10.1111	10.1111	NUM
dpc-1303	246	4	/	/	SYM
dpc-1303	246	5	dth.12327	dth.12327	PROPN
dpc-1303	246	6	.	.	PUNCT
dpc-1303	247	1	pmid	pmid	NOUN
dpc-1303	247	2	:	:	PUNCT
dpc-1303	247	3	26800435	26800435	NUM
dpc-1303	247	4	.	.	PUNCT
dpc-1303	248	1	22	22	NUM
dpc-1303	248	2	.	.	PUNCT
dpc-1303	249	1	yuan	yuan	NOUN
dpc-1303	249	2	h	h	PROPN
dpc-1303	249	3	,	,	PUNCT
dpc-1303	249	4	zhou	zhou	PROPN
dpc-1303	249	5	s	s	PROPN
dpc-1303	249	6	,	,	PUNCT
dpc-1303	249	7	liu	liu	PROPN
dpc-1303	249	8	z	z	PROPN
dpc-1303	249	9	,	,	PUNCT
dpc-1303	249	10	et	et	PROPN
dpc-1303	249	11	al	al	PROPN
dpc-1303	249	12	.	.	PUNCT
dpc-1303	250	1	pivotal	pivotal	ADJ
dpc-1303	250	2	role	role	NOUN
dpc-1303	250	3	of	of	ADP
dpc-1303	250	4	lesional	lesional	ADJ
dpc-1303	250	5	and	and	CCONJ
dpc-1303	250	6	perilesional	perilesional	PROPN
dpc-1303	250	7	t	t	PROPN
dpc-1303	250	8	/	/	SYM
dpc-1303	250	9	b	b	PROPN
dpc-1303	250	10	lymphocytes	lymphocyte	NOUN
dpc-1303	250	11	in	in	ADP
dpc-1303	250	12	pemphigus	pemphigus	NOUN
dpc-1303	250	13	pathogenesis	pathogenesis	NOUN
dpc-1303	250	14	.	.	PUNCT
dpc-1303	251	1	j	j	PROPN
dpc-1303	251	2	invest	invest	VERB
dpc-1303	251	3	dermatol	dermatol	NOUN
dpc-1303	251	4	.	.	PUNCT
dpc-1303	252	1	2017;137(11):2362	2017;137(11):2362	PROPN
dpc-1303	252	2	-	-	PUNCT
dpc-1303	252	3	2370	2370	NUM
dpc-1303	252	4	.	.	PUNCT
dpc-1303	253	1	doi	doi	NOUN
dpc-1303	253	2	:	:	PUNCT
dpc-1303	253	3	10.1016	10.1016	NUM
dpc-1303	253	4	/	/	SYM
dpc-1303	253	5	j.	j.	PROPN
dpc-1303	253	6	jid.2017.05.032	jid.2017.05.032	PROPN
dpc-1303	253	7	.	.	PUNCT
dpc-1303	254	1	pmid	pmid	NOUN
dpc-1303	254	2	:	:	PUNCT
dpc-1303	254	3	28647348	28647348	NUM
dpc-1303	254	4	.	.	PUNCT
dpc-1303	255	1	23	23	NUM
dpc-1303	255	2	.	.	PUNCT
dpc-1303	256	1	tavakolpour	tavakolpour	NUM
dpc-1303	256	2	s.	s.	PROPN
dpc-1303	256	3	towards	towards	ADP
dpc-1303	256	4	personalized	personalized	ADJ
dpc-1303	256	5	medicine	medicine	NOUN
dpc-1303	256	6	for	for	ADP
dpc-1303	256	7	patients	patient	NOUN
dpc-1303	256	8	with	with	ADP
dpc-1303	256	9	autoimmune	autoimmune	ADJ
dpc-1303	256	10	diseases	disease	NOUN
dpc-1303	256	11	:	:	PUNCT
dpc-1303	256	12	opportunities	opportunity	NOUN
dpc-1303	256	13	and	and	CCONJ
dpc-1303	256	14	challenges	challenge	NOUN
dpc-1303	256	15	.	.	PUNCT
dpc-1303	257	1	immunol	immunol	NOUN
dpc-1303	257	2	letters	letter	NOUN
dpc-1303	257	3	.	.	PUNCT
dpc-1303	258	1	2017;190:130	2017;190:130	NUM
dpc-1303	258	2	-	-	SYM
dpc-1303	258	3	138	138	NUM
dpc-1303	258	4	.	.	PUNCT
dpc-1303	259	1	doi	doi	NOUN
dpc-1303	259	2	:	:	PUNCT
dpc-1303	259	3	10.1016	10.1016	NUM
dpc-1303	259	4	/	/	SYM
dpc-1303	259	5	j.imlet.2017.08.002	j.imlet.2017.08.002	NOUN
dpc-1303	259	6	.	.	PUNCT
dpc-1303	260	1	pmid	pmid	NOUN
dpc-1303	260	2	:	:	PUNCT
dpc-1303	260	3	28797806	28797806	NUM
dpc-1303	260	4	.	.	PUNCT
dpc-1303	261	1	24	24	NUM
dpc-1303	261	2	.	.	PUNCT
dpc-1303	262	1	tavakolpour	tavakolpour	NUM
dpc-1303	262	2	s	s	PROPN
dpc-1303	262	3	,	,	PUNCT
dpc-1303	262	4	mahmoudi	mahmoudi	ADJ
dpc-1303	262	5	h	h	NOUN
dpc-1303	262	6	,	,	PUNCT
dpc-1303	262	7	karami	karami	PROPN
dpc-1303	262	8	f	f	AUX
dpc-1303	262	9	,	,	PUNCT
dpc-1303	262	10	et	et	PROPN
dpc-1303	262	11	al	al	PROPN
dpc-1303	262	12	.	.	PUNCT
dpc-1303	262	13	investigating	investigate	VERB
dpc-1303	262	14	expression	expression	NOUN
dpc-1303	262	15	pattern	pattern	NOUN
dpc-1303	262	16	of	of	ADP
dpc-1303	262	17	eight	eight	NUM
dpc-1303	262	18	immune	immune	NOUN
dpc-1303	262	19	-	-	PUNCT
dpc-1303	262	20	related	relate	VERB
dpc-1303	262	21	genes	gene	NOUN
dpc-1303	262	22	in	in	ADP
dpc-1303	262	23	pemphigus	pemphigus	NOUN
dpc-1303	262	24	patients	patient	NOUN
dpc-1303	262	25	compared	compare	VERB
dpc-1303	262	26	with	with	ADP
dpc-1303	262	27	the	the	DET
dpc-1303	262	28	healthy	healthy	ADJ
dpc-1303	262	29	controls	control	NOUN
dpc-1303	262	30	and	and	CCONJ
dpc-1303	262	31	after	after	ADP
dpc-1303	262	32	rituximab	rituximab	NOUN
dpc-1303	262	33	therapy	therapy	NOUN
dpc-1303	262	34	:	:	PUNCT
dpc-1303	262	35	potentials	potential	VERB
dpc-1303	262	36	roles	role	NOUN
dpc-1303	262	37	of	of	ADP
dpc-1303	262	38	ctla4	ctla4	NOUN
dpc-1303	262	39	and	and	CCONJ
dpc-1303	262	40	fcgr3a	fcgr3a	ADJ
dpc-1303	262	41	genes	gene	NOUN
dpc-1303	262	42	expressio	expressio	ADJ
dpc-1303	262	43	in	in	ADP
dpc-1303	262	44	outcomes	outcome	NOUN
dpc-1303	262	45	of	of	ADP
dpc-1303	262	46	rituximab	rituximab	NOUN
dpc-1303	262	47	therapy	therapy	NOUN
dpc-1303	262	48	.	.	PUNCT
dpc-1303	263	1	dermatol	dermatol	NOUN
dpc-1303	263	2	ther	ther	ADV
dpc-1303	263	3	.	.	PUNCT
dpc-1303	264	1	2020;33(6):e14380	2020;33(6):e14380	X
dpc-1303	264	2	.	.	PUNCT
dpc-1303	265	1	doi	doi	NOUN
dpc-1303	265	2	:	:	PUNCT
dpc-1303	265	3	10.111	10.111	NUM
dpc-1303	265	4	/	/	SYM
dpc-1303	265	5	dth.14380	dth.14380	NOUN
dpc-1303	265	6	.	.	PUNCT
dpc-1303	266	1	pmid	pmid	NOUN
dpc-1303	266	2	:	:	PUNCT
dpc-1303	266	3	33090639	33090639	NUM
dpc-1303	266	4	.	.	PUNCT
dpc-1303	267	1	25	25	NUM
dpc-1303	267	2	.	.	PUNCT
dpc-1303	267	3	balighi	balighi	PROPN
dpc-1303	267	4	k	k	PROPN
dpc-1303	267	5	,	,	PUNCT
dpc-1303	267	6	daneshpazhooh	daneshpazhooh	VERB
dpc-1303	267	7	m	m	PROPN
dpc-1303	267	8	,	,	PUNCT
dpc-1303	267	9	akbari	akbari	PROPN
dpc-1303	267	10	z	z	PROPN
dpc-1303	267	11	,	,	PUNCT
dpc-1303	267	12	tavakolpour	tavakolpour	PROPN
dpc-1303	267	13	s	s	NOUN
dpc-1303	267	14	,	,	PUNCT
dpc-1303	267	15	azimi	azimi	NOUN
dpc-1303	267	16	p	p	NOUN
dpc-1303	267	17	,	,	PUNCT
dpc-1303	267	18	azizpour	azizpour	ADJ
dpc-1303	267	19	a.	a.	NOUN
dpc-1303	267	20	comparing	compare	VERB
dpc-1303	267	21	the	the	DET
dpc-1303	267	22	short	short	ADJ
dpc-1303	267	23	-	-	PUNCT
dpc-1303	267	24	term	term	NOUN
dpc-1303	267	25	therapeutic	therapeutic	ADJ
dpc-1303	267	26	effects	effect	NOUN
dpc-1303	267	27	and	and	CCONJ
dpc-1303	267	28	safety	safety	NOUN
dpc-1303	267	29	profiles	profile	NOUN
dpc-1303	267	30	of	of	ADP
dpc-1303	267	31	rituximab	rituximab	NOUN
dpc-1303	267	32	therapy	therapy	NOUN
dpc-1303	267	33	in	in	ADP
dpc-1303	267	34	pemphigus	pemphigus	NOUN
dpc-1303	267	35	vulgaris	vulgaris	NOUN
dpc-1303	267	36	patients	patient	NOUN
dpc-1303	267	37	either	either	CCONJ
dpc-1303	267	38	early	early	ADV
dpc-1303	267	39	treated	treat	VERB
dpc-1303	267	40	or	or	CCONJ
dpc-1303	267	41	later	late	ADJ
dpc-1303	267	42	than	than	ADP
dpc-1303	267	43	six	six	NUM
dpc-1303	267	44	months	month	NOUN
dpc-1303	267	45	.	.	PUNCT
dpc-1303	268	1	j	j	PROPN
dpc-1303	268	2	dermatolog	dermatolog	PROPN
dpc-1303	268	3	treat	treat	NOUN
dpc-1303	268	4	.	.	PUNCT
dpc-1303	269	1	2018:1	2018:1	NUM
dpc-1303	269	2	-	-	SYM
dpc-1303	269	3	4	4	NUM
dpc-1303	269	4	.	.	PUNCT
dpc-1303	269	5	doi	doi	NOUN
dpc-1303	269	6	:	:	PUNCT
dpc-1303	269	7	10.1080/09546634.2018.1509049	10.1080/09546634.2018.1509049	NUM
dpc-1303	269	8	.	.	PUNCT
dpc-1303	270	1	pmid	pmid	NOUN
dpc-1303	270	2	:	:	PUNCT
dpc-1303	270	3	30081690	30081690	NUM
dpc-1303	270	4	.	.	PUNCT