id	sid	tid	token	lemma	pos
dpc-1620	1	1	dermatology	dermatology	NOUN
dpc-1620	1	2	:	:	PUNCT
dpc-1620	1	3	practical	practical	ADJ
dpc-1620	1	4	and	and	CCONJ
dpc-1620	1	5	conceptual	conceptual	ADJ
dpc-1620	1	6	dermatology	dermatology	NOUN
dpc-1620	1	7	practical	practical	ADJ
dpc-1620	1	8	&	&	CCONJ
dpc-1620	1	9	conceptual	conceptual	ADJ
dpc-1620	1	10	review	review	NOUN
dpc-1620	1	11	|	|	ADV
dpc-1620	1	12	dermatol	dermatol	ADJ
dpc-1620	1	13	pract	pract	NOUN
dpc-1620	1	14	concept	concept	NOUN
dpc-1620	1	15	.	.	PUNCT
dpc-1620	2	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	2	2	2021068	2021068	NUM
dpc-1620	2	3	1	1	NUM
dpc-1620	2	4	reflectance	reflectance	NOUN
dpc-1620	2	5	confocal	confocal	ADJ
dpc-1620	2	6	microscopy	microscopy	NOUN
dpc-1620	2	7	of	of	ADP
dpc-1620	2	8	aging	age	VERB
dpc-1620	2	9	skin	skin	NOUN
dpc-1620	2	10	and	and	CCONJ
dpc-1620	2	11	skin	skin	NOUN
dpc-1620	2	12	cancer	cancer	NOUN
dpc-1620	2	13	stefania	stefania	NOUN
dpc-1620	2	14	guida1	guida1	PROPN
dpc-1620	2	15	,	,	PUNCT
dpc-1620	2	16	giovanni	giovanni	PROPN
dpc-1620	2	17	pellacani1,3	pellacani1,3	PROPN
dpc-1620	2	18	,	,	PUNCT
dpc-1620	2	19	silvana	silvana	PROPN
dpc-1620	2	20	ciardo1	ciardo1	PROPN
dpc-1620	2	21	,	,	PUNCT
dpc-1620	2	22	caterina	caterina	PROPN
dpc-1620	2	23	longo1,2	longo1,2	ADJ
dpc-1620	2	24	1	1	NUM
dpc-1620	2	25	dermatology	dermatology	NOUN
dpc-1620	2	26	unit	unit	NOUN
dpc-1620	2	27	,	,	PUNCT
dpc-1620	2	28	department	department	NOUN
dpc-1620	2	29	of	of	ADP
dpc-1620	2	30	surgical	surgical	ADJ
dpc-1620	2	31	,	,	PUNCT
dpc-1620	2	32	medical	medical	ADJ
dpc-1620	2	33	,	,	PUNCT
dpc-1620	2	34	dental	dental	ADJ
dpc-1620	2	35	and	and	CCONJ
dpc-1620	2	36	morphological	morphological	ADJ
dpc-1620	2	37	sciences	science	NOUN
dpc-1620	2	38	related	relate	VERB
dpc-1620	2	39	to	to	ADP
dpc-1620	2	40	transplant	transplant	NOUN
dpc-1620	2	41	,	,	PUNCT
dpc-1620	2	42	oncology	oncology	NOUN
dpc-1620	2	43	and	and	CCONJ
dpc-1620	2	44	regenerative	regenerative	ADJ
dpc-1620	2	45	medicine	medicine	NOUN
dpc-1620	2	46	,	,	PUNCT
dpc-1620	2	47	university	university	NOUN
dpc-1620	2	48	of	of	ADP
dpc-1620	2	49	modena	modena	PROPN
dpc-1620	2	50	and	and	CCONJ
dpc-1620	2	51	reggio	reggio	PROPN
dpc-1620	2	52	emilia	emilia	PROPN
dpc-1620	2	53	,	,	PUNCT
dpc-1620	2	54	modena	modena	PROPN
dpc-1620	2	55	,	,	PUNCT
dpc-1620	2	56	italy	italy	PROPN
dpc-1620	2	57	2	2	NUM
dpc-1620	2	58	centro	centro	X
dpc-1620	2	59	oncologico	oncologico	NOUN
dpc-1620	2	60	ad	ad	PROPN
dpc-1620	2	61	alta	alta	PROPN
dpc-1620	2	62	tecnologia	tecnologia	PROPN
dpc-1620	2	63	diagnostica	diagnostica	PROPN
dpc-1620	2	64	,	,	PUNCT
dpc-1620	2	65	azienda	azienda	PROPN
dpc-1620	2	66	unità	unità	PROPN
dpc-1620	2	67	sanitaria	sanitaria	PROPN
dpc-1620	2	68	locale	locale	PROPN
dpc-1620	2	69	-	-	PUNCT
dpc-1620	2	70	istituto	istituto	X
dpc-1620	2	71	di	di	X
dpc-1620	2	72	ricovero	ricovero	PROPN
dpc-1620	2	73	e	e	PROPN
dpc-1620	2	74	cura	cura	PROPN
dpc-1620	2	75	a	a	PROPN
dpc-1620	2	76	carattere	carattere	PROPN
dpc-1620	2	77	scientifico	scientifico	PROPN
dpc-1620	2	78	di	di	PROPN
dpc-1620	2	79	reggio	reggio	PROPN
dpc-1620	2	80	emilia	emilia	PROPN
dpc-1620	2	81	,	,	PUNCT
dpc-1620	2	82	reggio	reggio	PROPN
dpc-1620	2	83	emilia	emilia	PROPN
dpc-1620	2	84	,	,	PUNCT
dpc-1620	2	85	italy	italy	PROPN
dpc-1620	2	86	3	3	NUM
dpc-1620	2	87	dermatologic	dermatologic	ADJ
dpc-1620	2	88	unit	unit	NOUN
dpc-1620	2	89	,	,	PUNCT
dpc-1620	2	90	department	department	NOUN
dpc-1620	2	91	of	of	ADP
dpc-1620	2	92	clinical	clinical	ADJ
dpc-1620	2	93	internal	internal	ADJ
dpc-1620	2	94	,	,	PUNCT
dpc-1620	2	95	anesthesiological	anesthesiological	ADJ
dpc-1620	2	96	and	and	CCONJ
dpc-1620	2	97	cardiovascular	cardiovascular	ADJ
dpc-1620	2	98	sciences	science	NOUN
dpc-1620	2	99	,	,	PUNCT
dpc-1620	2	100	sapienza	sapienza	PROPN
dpc-1620	2	101	university	university	PROPN
dpc-1620	2	102	of	of	ADP
dpc-1620	2	103	rome	rome	PROPN
dpc-1620	2	104	,	,	PUNCT
dpc-1620	2	105	rome	rome	PROPN
dpc-1620	2	106	,	,	PUNCT
dpc-1620	2	107	italy	italy	PROPN
dpc-1620	2	108	.	.	PUNCT
dpc-1620	3	1	key	key	ADJ
dpc-1620	3	2	words	word	NOUN
dpc-1620	3	3	:	:	PUNCT
dpc-1620	3	4	skin	skin	NOUN
dpc-1620	3	5	aging	aging	NOUN
dpc-1620	3	6	,	,	PUNCT
dpc-1620	3	7	skin	skin	NOUN
dpc-1620	3	8	cancer	cancer	NOUN
dpc-1620	3	9	,	,	PUNCT
dpc-1620	3	10	collagen	collagen	NOUN
dpc-1620	3	11	,	,	PUNCT
dpc-1620	3	12	blood	blood	NOUN
dpc-1620	3	13	vessels	vessel	NOUN
dpc-1620	3	14	,	,	PUNCT
dpc-1620	3	15	reflectance	reflectance	NOUN
dpc-1620	3	16	confocal	confocal	ADJ
dpc-1620	3	17	microscopy	microscopy	NOUN
dpc-1620	3	18	citation	citation	NOUN
dpc-1620	3	19	:	:	PUNCT
dpc-1620	3	20	guida	guida	PROPN
dpc-1620	3	21	s	s	PROPN
dpc-1620	3	22	,	,	PUNCT
dpc-1620	3	23	ciardo	ciardo	NOUN
dpc-1620	3	24	s	s	NOUN
dpc-1620	3	25	,	,	PUNCT
dpc-1620	3	26	pellacani	pellacani	VERB
dpc-1620	3	27	g	g	PROPN
dpc-1620	3	28	,	,	PUNCT
dpc-1620	3	29	longo	longo	PROPN
dpc-1620	3	30	c.	c.	PROPN
dpc-1620	3	31	skin	skin	NOUN
dpc-1620	3	32	aging	aging	NOUN
dpc-1620	3	33	and	and	CCONJ
dpc-1620	3	34	skin	skin	NOUN
dpc-1620	3	35	cancer	cancer	NOUN
dpc-1620	3	36	:	:	PUNCT
dpc-1620	3	37	reflectance	reflectance	NOUN
dpc-1620	3	38	confocal	confocal	ADJ
dpc-1620	3	39	microscopy	microscopy	NOUN
dpc-1620	3	40	of	of	ADP
dpc-1620	3	41	skin	skin	NOUN
dpc-1620	3	42	aging	aging	NOUN
dpc-1620	3	43	and	and	CCONJ
dpc-1620	3	44	skin	skin	NOUN
dpc-1620	3	45	cancer	cancer	NOUN
dpc-1620	3	46	.	.	PUNCT
dpc-1620	4	1	dermatol	dermatol	NOUN
dpc-1620	4	2	pract	pract	PROPN
dpc-1620	4	3	concept	concept	NOUN
dpc-1620	4	4	.	.	PUNCT
dpc-1620	5	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	5	2	2021068	2021068	NUM
dpc-1620	5	3	.	.	PUNCT
dpc-1620	6	1	doi	doi	NOUN
dpc-1620	6	2	:	:	PUNCT
dpc-1620	6	3	https://doi.org/10.5826/dpc.1103a68	https://doi.org/10.5826/dpc.1103a68	PUNCT
dpc-1620	6	4	accepted	accept	VERB
dpc-1620	6	5	:	:	PUNCT
dpc-1620	6	6	february	february	PROPN
dpc-1620	6	7	3	3	NUM
dpc-1620	6	8	,	,	PUNCT
dpc-1620	6	9	2021	2021	NUM
dpc-1620	6	10	;	;	PUNCT
dpc-1620	6	11	published	publish	VERB
dpc-1620	6	12	:	:	PUNCT
dpc-1620	6	13	may	may	AUX
dpc-1620	6	14	20	20	NUM
dpc-1620	6	15	,	,	PUNCT
dpc-1620	6	16	2021	2021	NUM
dpc-1620	6	17	copyright	copyright	NOUN
dpc-1620	6	18	:	:	PUNCT
dpc-1620	7	1	©	©	PROPN
dpc-1620	7	2	2021	2021	NUM
dpc-1620	7	3	guida	guida	PROPN
dpc-1620	7	4	et	et	PROPN
dpc-1620	7	5	al	al	PROPN
dpc-1620	7	6	.	.	PUNCT
dpc-1620	8	1	this	this	PRON
dpc-1620	8	2	is	be	AUX
dpc-1620	8	3	an	an	DET
dpc-1620	8	4	open	open	ADJ
dpc-1620	8	5	-	-	PUNCT
dpc-1620	8	6	access	access	NOUN
dpc-1620	8	7	article	article	NOUN
dpc-1620	8	8	distributed	distribute	VERB
dpc-1620	8	9	under	under	ADP
dpc-1620	8	10	the	the	DET
dpc-1620	8	11	terms	term	NOUN
dpc-1620	8	12	of	of	ADP
dpc-1620	8	13	the	the	DET
dpc-1620	8	14	creative	creative	ADJ
dpc-1620	8	15	commons	common	NOUN
dpc-1620	8	16	attribution	attribution	NOUN
dpc-1620	8	17	license	license	NOUN
dpc-1620	8	18	by	by	ADP
dpc-1620	8	19	-	-	PUNCT
dpc-1620	8	20	nc-4.0	nc-4.0	NOUN
dpc-1620	8	21	,	,	PUNCT
dpc-1620	8	22	which	which	PRON
dpc-1620	8	23	permits	permit	VERB
dpc-1620	8	24	unrestricted	unrestricted	ADJ
dpc-1620	8	25	noncommercial	noncommercial	ADJ
dpc-1620	8	26	use	use	NOUN
dpc-1620	8	27	,	,	PUNCT
dpc-1620	8	28	distribution	distribution	NOUN
dpc-1620	8	29	,	,	PUNCT
dpc-1620	8	30	and	and	CCONJ
dpc-1620	8	31	reproduction	reproduction	NOUN
dpc-1620	8	32	in	in	ADP
dpc-1620	8	33	any	any	DET
dpc-1620	8	34	medium	medium	NOUN
dpc-1620	8	35	,	,	PUNCT
dpc-1620	8	36	provided	provide	VERB
dpc-1620	8	37	the	the	DET
dpc-1620	8	38	original	original	ADJ
dpc-1620	8	39	authors	author	NOUN
dpc-1620	8	40	and	and	CCONJ
dpc-1620	8	41	source	source	NOUN
dpc-1620	8	42	are	be	AUX
dpc-1620	8	43	credited	credit	VERB
dpc-1620	8	44	.	.	PUNCT
dpc-1620	9	1	funding	funding	NOUN
dpc-1620	9	2	:	:	PUNCT
dpc-1620	9	3	none	none	NOUN
dpc-1620	9	4	.	.	PUNCT
dpc-1620	10	1	competing	compete	VERB
dpc-1620	10	2	interests	interest	NOUN
dpc-1620	10	3	:	:	PUNCT
dpc-1620	10	4	the	the	DET
dpc-1620	10	5	authors	author	NOUN
dpc-1620	10	6	have	have	VERB
dpc-1620	10	7	no	no	DET
dpc-1620	10	8	conflicts	conflict	NOUN
dpc-1620	10	9	of	of	ADP
dpc-1620	10	10	interest	interest	NOUN
dpc-1620	10	11	to	to	PART
dpc-1620	10	12	disclose	disclose	VERB
dpc-1620	10	13	.	.	PUNCT
dpc-1620	11	1	authorship	authorship	NOUN
dpc-1620	11	2	:	:	PUNCT
dpc-1620	11	3	all	all	DET
dpc-1620	11	4	authors	author	NOUN
dpc-1620	11	5	have	have	AUX
dpc-1620	11	6	contributed	contribute	VERB
dpc-1620	11	7	significantly	significantly	ADV
dpc-1620	11	8	to	to	ADP
dpc-1620	11	9	this	this	DET
dpc-1620	11	10	publication	publication	NOUN
dpc-1620	11	11	.	.	PUNCT
dpc-1620	12	1	corresponding	correspond	VERB
dpc-1620	12	2	author	author	NOUN
dpc-1620	12	3	:	:	PUNCT
dpc-1620	12	4	stefania	stefania	PROPN
dpc-1620	12	5	guida	guida	PROPN
dpc-1620	12	6	,	,	PUNCT
dpc-1620	12	7	md	md	PROPN
dpc-1620	12	8	,	,	PUNCT
dpc-1620	12	9	phd	phd	NOUN
dpc-1620	12	10	,	,	PUNCT
dpc-1620	12	11	dermatology	dermatology	NOUN
dpc-1620	12	12	unit	unit	NOUN
dpc-1620	12	13	,	,	PUNCT
dpc-1620	12	14	department	department	NOUN
dpc-1620	12	15	of	of	ADP
dpc-1620	12	16	surgical	surgical	ADJ
dpc-1620	12	17	,	,	PUNCT
dpc-1620	12	18	medical	medical	ADJ
dpc-1620	12	19	,	,	PUNCT
dpc-1620	12	20	dental	dental	ADJ
dpc-1620	12	21	and	and	CCONJ
dpc-1620	12	22	morphological	morphological	ADJ
dpc-1620	12	23	sciences	science	NOUN
dpc-1620	12	24	related	relate	VERB
dpc-1620	12	25	to	to	ADP
dpc-1620	12	26	transplant	transplant	NOUN
dpc-1620	12	27	,	,	PUNCT
dpc-1620	12	28	oncology	oncology	NOUN
dpc-1620	12	29	and	and	CCONJ
dpc-1620	12	30	regenerative	regenerative	ADJ
dpc-1620	12	31	medicine	medicine	NOUN
dpc-1620	12	32	,	,	PUNCT
dpc-1620	12	33	university	university	NOUN
dpc-1620	12	34	of	of	ADP
dpc-1620	12	35	modena	modena	PROPN
dpc-1620	12	36	and	and	CCONJ
dpc-1620	12	37	reggio	reggio	PROPN
dpc-1620	12	38	emilia	emilia	PROPN
dpc-1620	12	39	,	,	PUNCT
dpc-1620	12	40	via	via	ADP
dpc-1620	12	41	del	del	PROPN
dpc-1620	12	42	pozzo	pozzo	PROPN
dpc-1620	12	43	,	,	PUNCT
dpc-1620	12	44	71	71	NUM
dpc-1620	12	45	,	,	PUNCT
dpc-1620	12	46	modena	modena	PROPN
dpc-1620	12	47	411125	411125	NUM
dpc-1620	12	48	,	,	PUNCT
dpc-1620	12	49	italy	italy	PROPN
dpc-1620	12	50	.	.	PUNCT
dpc-1620	13	1	email	email	NOUN
dpc-1620	13	2	:	:	PUNCT
dpc-1620	14	1	drstefaniaguida@gmail.com	drstefaniaguida@gmail.com	X
dpc-1620	14	2	skin	skin	NOUN
dpc-1620	14	3	aging	aging	NOUN
dpc-1620	14	4	is	be	AUX
dpc-1620	14	5	a	a	DET
dpc-1620	14	6	complex	complex	ADJ
dpc-1620	14	7	process	process	NOUN
dpc-1620	14	8	that	that	PRON
dpc-1620	14	9	causes	cause	VERB
dpc-1620	14	10	morphologic	morphologic	ADJ
dpc-1620	14	11	variations	variation	NOUN
dpc-1620	14	12	.	.	PUNCT
dpc-1620	15	1	some	some	PRON
dpc-1620	15	2	of	of	ADP
dpc-1620	15	3	these	these	DET
dpc-1620	15	4	variations	variation	NOUN
dpc-1620	15	5	have	have	AUX
dpc-1620	15	6	been	be	AUX
dpc-1620	15	7	hypothesized	hypothesize	VERB
dpc-1620	15	8	to	to	PART
dpc-1620	15	9	be	be	AUX
dpc-1620	15	10	involved	involve	VERB
dpc-1620	15	11	in	in	ADP
dpc-1620	15	12	skin	skin	NOUN
dpc-1620	15	13	cancer	cancer	NOUN
dpc-1620	15	14	development	development	NOUN
dpc-1620	15	15	.	.	PUNCT
dpc-1620	16	1	this	this	DET
dpc-1620	16	2	paper	paper	NOUN
dpc-1620	16	3	reviews	review	VERB
dpc-1620	16	4	current	current	ADJ
dpc-1620	16	5	knowledge	knowledge	NOUN
dpc-1620	16	6	of	of	ADP
dpc-1620	16	7	the	the	DET
dpc-1620	16	8	features	feature	NOUN
dpc-1620	16	9	of	of	ADP
dpc-1620	16	10	aged	aged	ADJ
dpc-1620	16	11	skin	skin	NOUN
dpc-1620	16	12	as	as	SCONJ
dpc-1620	16	13	seen	see	VERB
dpc-1620	16	14	with	with	ADP
dpc-1620	16	15	reflectance	reflectance	NOUN
dpc-1620	16	16	confocal	confocal	ADJ
dpc-1620	16	17	microscopy	microscopy	NOUN
dpc-1620	16	18	(	(	PUNCT
dpc-1620	16	19	rcm	rcm	PROPN
dpc-1620	16	20	)	)	PUNCT
dpc-1620	16	21	.	.	PUNCT
dpc-1620	17	1	basic	basic	ADJ
dpc-1620	17	2	principles	principle	NOUN
dpc-1620	17	3	of	of	ADP
dpc-1620	17	4	the	the	DET
dpc-1620	17	5	technique	technique	NOUN
dpc-1620	17	6	are	be	AUX
dpc-1620	17	7	described	describe	VERB
dpc-1620	17	8	,	,	PUNCT
dpc-1620	17	9	and	and	CCONJ
dpc-1620	17	10	the	the	DET
dpc-1620	17	11	rcm	rcm	PROPN
dpc-1620	17	12	features	feature	NOUN
dpc-1620	17	13	of	of	ADP
dpc-1620	17	14	healthy	healthy	ADJ
dpc-1620	17	15	skin	skin	NOUN
dpc-1620	17	16	and	and	CCONJ
dpc-1620	17	17	skin	skin	NOUN
dpc-1620	17	18	cancer	cancer	NOUN
dpc-1620	17	19	are	be	AUX
dpc-1620	17	20	briefly	briefly	ADV
dpc-1620	17	21	discussed	discuss	VERB
dpc-1620	17	22	.	.	PUNCT
dpc-1620	18	1	moreover	moreover	ADV
dpc-1620	18	2	,	,	PUNCT
dpc-1620	18	3	the	the	DET
dpc-1620	18	4	rcm	rcm	PROPN
dpc-1620	18	5	features	feature	VERB
dpc-1620	18	6	at	at	ADP
dpc-1620	18	7	different	different	ADJ
dpc-1620	18	8	layers	layer	NOUN
dpc-1620	18	9	of	of	ADP
dpc-1620	18	10	young	young	ADJ
dpc-1620	18	11	and	and	CCONJ
dpc-1620	18	12	elderly	elderly	ADJ
dpc-1620	18	13	skin	skin	NOUN
dpc-1620	18	14	are	be	AUX
dpc-1620	18	15	described	describe	VERB
dpc-1620	18	16	,	,	PUNCT
dpc-1620	18	17	as	as	SCONJ
dpc-1620	18	18	are	be	AUX
dpc-1620	18	19	the	the	DET
dpc-1620	18	20	variations	variation	NOUN
dpc-1620	18	21	that	that	PRON
dpc-1620	18	22	occur	occur	VERB
dpc-1620	18	23	with	with	ADP
dpc-1620	18	24	passing	pass	VERB
dpc-1620	18	25	years	year	NOUN
dpc-1620	18	26	and	and	CCONJ
dpc-1620	18	27	in	in	ADP
dpc-1620	18	28	relation	relation	NOUN
dpc-1620	18	29	to	to	ADP
dpc-1620	18	30	sun	sun	NOUN
dpc-1620	18	31	exposure	exposure	NOUN
dpc-1620	18	32	that	that	PRON
dpc-1620	18	33	contribute	contribute	VERB
dpc-1620	18	34	to	to	ADP
dpc-1620	18	35	photoaging	photoaging	NOUN
dpc-1620	18	36	and	and	CCONJ
dpc-1620	18	37	the	the	DET
dpc-1620	18	38	development	development	NOUN
dpc-1620	18	39	of	of	ADP
dpc-1620	18	40	skin	skin	NOUN
dpc-1620	18	41	cancer	cancer	NOUN
dpc-1620	18	42	.	.	PUNCT
dpc-1620	19	1	rcm	rcm	PROPN
dpc-1620	19	2	enables	enable	VERB
dpc-1620	19	3	the	the	DET
dpc-1620	19	4	noninvasive	noninvasive	ADJ
dpc-1620	19	5	evaluation	evaluation	NOUN
dpc-1620	19	6	,	,	PUNCT
dpc-1620	19	7	at	at	ADP
dpc-1620	19	8	quasi	quasi	ADJ
dpc-1620	19	9	-	-	ADJ
dpc-1620	19	10	histologic	histologic	ADJ
dpc-1620	19	11	resolution	resolution	NOUN
dpc-1620	19	12	,	,	PUNCT
dpc-1620	19	13	of	of	ADP
dpc-1620	19	14	aging	age	VERB
dpc-1620	19	15	-	-	PUNCT
dpc-1620	19	16	related	relate	VERB
dpc-1620	19	17	skin	skin	NOUN
dpc-1620	19	18	changes	change	NOUN
dpc-1620	19	19	,	,	PUNCT
dpc-1620	19	20	some	some	PRON
dpc-1620	19	21	of	of	ADP
dpc-1620	19	22	which	which	PRON
dpc-1620	19	23	are	be	AUX
dpc-1620	19	24	shared	share	VERB
dpc-1620	19	25	with	with	ADP
dpc-1620	19	26	skin	skin	NOUN
dpc-1620	19	27	cancer	cancer	NOUN
dpc-1620	19	28	;	;	PUNCT
dpc-1620	19	29	this	this	DET
dpc-1620	19	30	ability	ability	NOUN
dpc-1620	19	31	helps	help	VERB
dpc-1620	19	32	avoid	avoid	VERB
dpc-1620	19	33	skin	skin	NOUN
dpc-1620	19	34	biopsy	biopsy	NOUN
dpc-1620	19	35	.	.	PUNCT
dpc-1620	20	1	further	further	ADJ
dpc-1620	20	2	research	research	NOUN
dpc-1620	20	3	is	be	AUX
dpc-1620	20	4	needed	need	VERB
dpc-1620	20	5	to	to	PART
dpc-1620	20	6	understand	understand	VERB
dpc-1620	20	7	the	the	DET
dpc-1620	20	8	relation	relation	NOUN
dpc-1620	20	9	between	between	ADP
dpc-1620	20	10	skin	skin	NOUN
dpc-1620	20	11	aging	aging	NOUN
dpc-1620	20	12	and	and	CCONJ
dpc-1620	20	13	skin	skin	NOUN
dpc-1620	20	14	cancer	cancer	NOUN
dpc-1620	20	15	development	development	NOUN
dpc-1620	20	16	.	.	PUNCT
dpc-1620	21	1	abstract	abstract	ADJ
dpc-1620	21	2	introduction	introduction	NOUN
dpc-1620	21	3	skin	skin	NOUN
dpc-1620	21	4	aging	aging	NOUN
dpc-1620	21	5	is	be	AUX
dpc-1620	21	6	a	a	DET
dpc-1620	21	7	complex	complex	ADJ
dpc-1620	21	8	biological	biological	ADJ
dpc-1620	21	9	process	process	NOUN
dpc-1620	21	10	leading	lead	VERB
dpc-1620	21	11	to	to	ADP
dpc-1620	21	12	skin	skin	NOUN
dpc-1620	21	13	senescence	senescence	NOUN
dpc-1620	21	14	.	.	PUNCT
dpc-1620	22	1	attention	attention	NOUN
dpc-1620	22	2	to	to	ADP
dpc-1620	22	3	skin	skin	NOUN
dpc-1620	22	4	aging	aging	NOUN
dpc-1620	22	5	reflects	reflect	VERB
dpc-1620	22	6	an	an	DET
dpc-1620	22	7	increasing	increase	VERB
dpc-1620	22	8	consumer	consumer	NOUN
dpc-1620	22	9	demand	demand	NOUN
dpc-1620	22	10	for	for	ADP
dpc-1620	22	11	products	product	NOUN
dpc-1620	22	12	and	and	CCONJ
dpc-1620	22	13	treatments	treatment	NOUN
dpc-1620	22	14	that	that	PRON
dpc-1620	22	15	can	can	AUX
dpc-1620	22	16	prevent	prevent	VERB
dpc-1620	22	17	or	or	CCONJ
dpc-1620	22	18	reverse	reverse	VERB
dpc-1620	22	19	skin	skin	NOUN
dpc-1620	22	20	aging	age	VERB
dpc-1620	22	21	signs	sign	NOUN
dpc-1620	22	22	[	[	X
dpc-1620	22	23	1,2	1,2	NUM
dpc-1620	22	24	]	]	PUNCT
dpc-1620	22	25	.	.	PUNCT
dpc-1620	23	1	importantly	importantly	ADV
dpc-1620	23	2	,	,	PUNCT
dpc-1620	23	3	aging	aging	NOUN
dpc-1620	23	4	is	be	AUX
dpc-1620	23	5	strongly	strongly	ADV
dpc-1620	23	6	associated	associate	VERB
dpc-1620	23	7	with	with	ADP
dpc-1620	23	8	skin	skin	NOUN
dpc-1620	23	9	cancer	cancer	NOUN
dpc-1620	23	10	development	development	NOUN
dpc-1620	23	11	.	.	PUNCT
dpc-1620	24	1	skin	skin	NOUN
dpc-1620	24	2	aging	aging	NOUN
dpc-1620	24	3	is	be	AUX
dpc-1620	24	4	influenced	influence	VERB
dpc-1620	24	5	by	by	ADP
dpc-1620	24	6	both	both	DET
dpc-1620	24	7	intrinsic	intrinsic	ADJ
dpc-1620	24	8	factors	factor	NOUN
dpc-1620	24	9	,	,	PUNCT
dpc-1620	24	10	such	such	ADJ
dpc-1620	24	11	as	as	ADP
dpc-1620	24	12	chronological	chronological	ADJ
dpc-1620	24	13	age	age	NOUN
dpc-1620	24	14	and	and	CCONJ
dpc-1620	24	15	genetic	genetic	ADJ
dpc-1620	24	16	background	background	NOUN
dpc-1620	24	17	,	,	PUNCT
dpc-1620	24	18	and	and	CCONJ
dpc-1620	24	19	extrinsic	extrinsic	ADJ
dpc-1620	24	20	factors	factor	NOUN
dpc-1620	24	21	,	,	PUNCT
dpc-1620	24	22	mainly	mainly	ADV
dpc-1620	24	23	sun	sun	NOUN
dpc-1620	24	24	exposure	exposure	NOUN
dpc-1620	24	25	,	,	PUNCT
dpc-1620	24	26	that	that	PRON
dpc-1620	24	27	contribute	contribute	VERB
dpc-1620	24	28	to	to	ADP
dpc-1620	24	29	“	"	PUNCT
dpc-1620	24	30	photoaging	photoage	VERB
dpc-1620	24	31	”	"	PUNCT
dpc-1620	25	1	[	[	X
dpc-1620	25	2	3	3	NUM
dpc-1620	25	3	]	]	PUNCT
dpc-1620	25	4	.	.	PUNCT
dpc-1620	26	1	interestingly	interestingly	ADV
dpc-1620	26	2	,	,	PUNCT
dpc-1620	26	3	different	different	ADJ
dpc-1620	26	4	types	type	NOUN
dpc-1620	26	5	of	of	ADP
dpc-1620	26	6	skin	skin	NOUN
dpc-1620	26	7	photoaging	photoage	VERB
dpc-1620	26	8	have	have	AUX
dpc-1620	26	9	been	be	AUX
dpc-1620	26	10	identified	identify	VERB
dpc-1620	26	11	:	:	PUNCT
dpc-1620	26	12	atrophic	atrophic	ADJ
dpc-1620	26	13	and	and	CCONJ
dpc-1620	26	14	hypertrophic	hypertrophic	ADJ
dpc-1620	26	15	.	.	PUNCT
dpc-1620	27	1	atrophic	atrophic	ADJ
dpc-1620	27	2	photoaging	photoaging	NOUN
dpc-1620	27	3	is	be	AUX
dpc-1620	27	4	typified	typify	VERB
dpc-1620	27	5	by	by	ADP
dpc-1620	27	6	actinic	actinic	ADJ
dpc-1620	27	7	keratosis	keratosis	NOUN
dpc-1620	27	8	,	,	PUNCT
dpc-1620	27	9	seborrheic	seborrheic	ADJ
dpc-1620	27	10	keratosis	keratosis	NOUN
dpc-1620	27	11	,	,	PUNCT
dpc-1620	27	12	telangiectasia	telangiectasia	NOUN
dpc-1620	27	13	,	,	PUNCT
dpc-1620	27	14	and	and	CCONJ
dpc-1620	27	15	a	a	DET
dpc-1620	27	16	prior	prior	ADJ
dpc-1620	27	17	diagnosis	diagnosis	NOUN
dpc-1620	27	18	of	of	ADP
dpc-1620	27	19	skin	skin	NOUN
dpc-1620	27	20	cancer	cancer	NOUN
dpc-1620	27	21	,	,	PUNCT
dpc-1620	27	22	while	while	SCONJ
dpc-1620	27	23	hypertrophic	hypertrophic	ADJ
dpc-1620	27	24	2	2	NUM
dpc-1620	27	25	review	review	NOUN
dpc-1620	27	26	|	|	ADV
dpc-1620	27	27	dermatol	dermatol	ADJ
dpc-1620	27	28	pract	pract	NOUN
dpc-1620	27	29	concept	concept	NOUN
dpc-1620	27	30	.	.	PUNCT
dpc-1620	28	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	28	2	2021068	2021068	NUM
dpc-1620	28	3	photoaging	photoage	VERB
dpc-1620	28	4	is	be	AUX
dpc-1620	28	5	characterized	characterize	VERB
dpc-1620	28	6	by	by	ADP
dpc-1620	28	7	high	high	ADJ
dpc-1620	28	8	scores	score	NOUN
dpc-1620	28	9	on	on	ADP
dpc-1620	28	10	photoaging	photoage	VERB
dpc-1620	28	11	severity	severity	NOUN
dpc-1620	28	12	scales	scale	NOUN
dpc-1620	28	13	,	,	PUNCT
dpc-1620	28	14	coarse	coarse	ADJ
dpc-1620	28	15	wrinkles	wrinkle	NOUN
dpc-1620	28	16	,	,	PUNCT
dpc-1620	28	17	thickness	thickness	NOUN
dpc-1620	28	18	,	,	PUNCT
dpc-1620	28	19	and	and	CCONJ
dpc-1620	28	20	sallowness	sallowness	ADJ
dpc-1620	28	21	[	[	X
dpc-1620	28	22	4	4	NUM
dpc-1620	28	23	]	]	PUNCT
dpc-1620	28	24	.	.	PUNCT
dpc-1620	29	1	uv	uv	NOUN
dpc-1620	29	2	irradiation	irradiation	NOUN
dpc-1620	29	3	,	,	PUNCT
dpc-1620	29	4	both	both	CCONJ
dpc-1620	29	5	natural	natural	ADJ
dpc-1620	29	6	and	and	CCONJ
dpc-1620	29	7	artificial	artificial	ADJ
dpc-1620	29	8	,	,	PUNCT
dpc-1620	29	9	is	be	AUX
dpc-1620	29	10	considered	consider	VERB
dpc-1620	29	11	the	the	DET
dpc-1620	29	12	main	main	ADJ
dpc-1620	29	13	etiologic	etiologic	ADJ
dpc-1620	29	14	factor	factor	NOUN
dpc-1620	29	15	in	in	ADP
dpc-1620	29	16	photoaging	photoage	VERB
dpc-1620	29	17	and	and	CCONJ
dpc-1620	29	18	skin	skin	NOUN
dpc-1620	29	19	cancer	cancer	NOUN
dpc-1620	29	20	.	.	PUNCT
dpc-1620	30	1	uv	uv	NOUN
dpc-1620	30	2	irradiation	irradiation	NOUN
dpc-1620	30	3	induces	induce	VERB
dpc-1620	30	4	dna	dna	ADJ
dpc-1620	30	5	damage	damage	NOUN
dpc-1620	30	6	(	(	PUNCT
dpc-1620	30	7	through	through	ADP
dpc-1620	30	8	the	the	DET
dpc-1620	30	9	formation	formation	NOUN
dpc-1620	30	10	of	of	ADP
dpc-1620	30	11	cyclobutane	cyclobutane	ADJ
dpc-1620	30	12	pyrimidine	pyrimidine	NOUN
dpc-1620	30	13	dimers	dimer	NOUN
dpc-1620	30	14	)	)	PUNCT
dpc-1620	30	15	,	,	PUNCT
dpc-1620	30	16	gene	gene	NOUN
dpc-1620	30	17	mutation	mutation	NOUN
dpc-1620	30	18	,	,	PUNCT
dpc-1620	30	19	oxidative	oxidative	ADJ
dpc-1620	30	20	stress	stress	NOUN
dpc-1620	30	21	,	,	PUNCT
dpc-1620	30	22	immunosuppression	immunosuppression	NOUN
dpc-1620	30	23	,	,	PUNCT
dpc-1620	30	24	and	and	CCONJ
dpc-1620	30	25	inflammatory	inflammatory	ADJ
dpc-1620	30	26	responses	response	NOUN
dpc-1620	30	27	[	[	X
dpc-1620	30	28	5,6	5,6	NUM
dpc-1620	30	29	]	]	PUNCT
dpc-1620	30	30	.	.	PUNCT
dpc-1620	31	1	in	in	ADP
dpc-1620	31	2	fact	fact	NOUN
dpc-1620	31	3	,	,	PUNCT
dpc-1620	31	4	painful	painful	ADJ
dpc-1620	31	5	sunburns	sunburn	NOUN
dpc-1620	31	6	have	have	AUX
dpc-1620	31	7	been	be	AUX
dpc-1620	31	8	associated	associate	VERB
dpc-1620	31	9	with	with	ADP
dpc-1620	31	10	the	the	DET
dpc-1620	31	11	development	development	NOUN
dpc-1620	31	12	of	of	ADP
dpc-1620	31	13	both	both	DET
dpc-1620	31	14	melanoma	melanoma	NOUN
dpc-1620	31	15	and	and	CCONJ
dpc-1620	31	16	non	non	ADJ
dpc-1620	31	17	-	-	ADJ
dpc-1620	31	18	melanoma	melanoma	ADJ
dpc-1620	31	19	skin	skin	NOUN
dpc-1620	31	20	cancers	cancer	NOUN
dpc-1620	31	21	(	(	PUNCT
dpc-1620	31	22	nmscs	nmscs	NOUN
dpc-1620	31	23	)	)	PUNCT
dpc-1620	31	24	,	,	PUNCT
dpc-1620	31	25	namely	namely	ADV
dpc-1620	31	26	squamous	squamous	ADJ
dpc-1620	31	27	cell	cell	NOUN
dpc-1620	31	28	carcinoma	carcinoma	NOUN
dpc-1620	31	29	(	(	PUNCT
dpc-1620	31	30	scc	scc	NOUN
dpc-1620	31	31	)	)	PUNCT
dpc-1620	31	32	and	and	CCONJ
dpc-1620	31	33	basal	basal	NOUN
dpc-1620	31	34	cell	cell	NOUN
dpc-1620	31	35	carcinoma	carcinoma	NOUN
dpc-1620	31	36	(	(	PUNCT
dpc-1620	31	37	bcc	bcc	PROPN
dpc-1620	31	38	)	)	PUNCT
dpc-1620	32	1	[	[	X
dpc-1620	32	2	5,7	5,7	NUM
dpc-1620	32	3	]	]	PUNCT
dpc-1620	32	4	,	,	PUNCT
dpc-1620	32	5	while	while	SCONJ
dpc-1620	32	6	chronic	chronic	ADJ
dpc-1620	32	7	sun	sun	NOUN
dpc-1620	32	8	exposure	exposure	NOUN
dpc-1620	32	9	is	be	AUX
dpc-1620	32	10	considered	consider	VERB
dpc-1620	32	11	the	the	DET
dpc-1620	32	12	most	most	ADV
dpc-1620	32	13	important	important	ADJ
dpc-1620	32	14	causative	causative	ADJ
dpc-1620	32	15	factor	factor	NOUN
dpc-1620	32	16	for	for	ADP
dpc-1620	32	17	actinic	actinic	ADJ
dpc-1620	32	18	keratosis	keratosis	NOUN
dpc-1620	32	19	and	and	CCONJ
dpc-1620	33	1	lentigo	lentigo	ADJ
dpc-1620	33	2	maligna	maligna	PROPN
dpc-1620	33	3	/	/	SYM
dpc-1620	33	4	lentigo	lentigo	PROPN
dpc-1620	33	5	maligna	maligna	NOUN
dpc-1620	33	6	melanoma	melanoma	PROPN
dpc-1620	33	7	(	(	PUNCT
dpc-1620	33	8	lm	lm	PROPN
dpc-1620	33	9	/	/	SYM
dpc-1620	33	10	lmm	lmm	PROPN
dpc-1620	33	11	)	)	PUNCT
dpc-1620	34	1	[	[	X
dpc-1620	34	2	5,8	5,8	NUM
dpc-1620	34	3	]	]	PUNCT
dpc-1620	34	4	.	.	PUNCT
dpc-1620	35	1	in	in	ADP
dpc-1620	35	2	the	the	DET
dpc-1620	35	3	past	past	ADJ
dpc-1620	35	4	few	few	ADJ
dpc-1620	35	5	years	year	NOUN
dpc-1620	35	6	,	,	PUNCT
dpc-1620	35	7	reflectance	reflectance	NOUN
dpc-1620	35	8	confocal	confocal	ADJ
dpc-1620	35	9	microscopy	microscopy	NOUN
dpc-1620	35	10	(	(	PUNCT
dpc-1620	35	11	rcm	rcm	PROPN
dpc-1620	35	12	)	)	PUNCT
dpc-1620	35	13	has	have	AUX
dpc-1620	35	14	been	be	AUX
dpc-1620	35	15	employed	employ	VERB
dpc-1620	35	16	as	as	ADP
dpc-1620	35	17	a	a	DET
dpc-1620	35	18	noninvasive	noninvasive	ADJ
dpc-1620	35	19	technique	technique	NOUN
dpc-1620	35	20	to	to	PART
dpc-1620	35	21	visualize	visualize	VERB
dpc-1620	35	22	the	the	DET
dpc-1620	35	23	skin	skin	NOUN
dpc-1620	35	24	at	at	ADP
dpc-1620	35	25	quasi	quasi	ADJ
dpc-1620	35	26	-	-	ADJ
dpc-1620	35	27	histological	histological	ADJ
dpc-1620	35	28	resolution	resolution	NOUN
dpc-1620	35	29	;	;	PUNCT
dpc-1620	35	30	it	it	PRON
dpc-1620	35	31	has	have	AUX
dpc-1620	35	32	also	also	ADV
dpc-1620	35	33	been	be	AUX
dpc-1620	35	34	used	use	VERB
dpc-1620	35	35	as	as	ADP
dpc-1620	35	36	an	an	DET
dpc-1620	35	37	add	add	VERB
dpc-1620	35	38	-	-	PUNCT
dpc-1620	35	39	on	on	ADP
dpc-1620	35	40	tool	tool	NOUN
dpc-1620	35	41	in	in	ADP
dpc-1620	35	42	the	the	DET
dpc-1620	35	43	diagnosis	diagnosis	NOUN
dpc-1620	35	44	of	of	ADP
dpc-1620	35	45	skin	skin	NOUN
dpc-1620	35	46	cancer	cancer	NOUN
dpc-1620	35	47	,	,	PUNCT
dpc-1620	35	48	as	as	ADP
dpc-1620	35	49	a	a	DET
dpc-1620	35	50	second	second	ADJ
dpc-1620	35	51	level	level	NOUN
dpc-1620	35	52	of	of	ADP
dpc-1620	35	53	examination	examination	NOUN
dpc-1620	35	54	after	after	ADP
dpc-1620	35	55	dermoscopy	dermoscopy	NOUN
dpc-1620	35	56	,	,	PUNCT
dpc-1620	35	57	to	to	PART
dpc-1620	35	58	improve	improve	VERB
dpc-1620	35	59	diagnostic	diagnostic	ADJ
dpc-1620	35	60	accuracy	accuracy	NOUN
dpc-1620	36	1	[	[	X
dpc-1620	36	2	9	9	NUM
dpc-1620	36	3	-	-	SYM
dpc-1620	36	4	12	12	NUM
dpc-1620	36	5	]	]	PUNCT
dpc-1620	36	6	.	.	PUNCT
dpc-1620	37	1	additionally	additionally	ADV
dpc-1620	37	2	,	,	PUNCT
dpc-1620	37	3	due	due	ADP
dpc-1620	37	4	to	to	ADP
dpc-1620	37	5	the	the	DET
dpc-1620	37	6	fact	fact	NOUN
dpc-1620	37	7	that	that	SCONJ
dpc-1620	37	8	rcm	rcm	PROPN
dpc-1620	37	9	avoids	avoid	VERB
dpc-1620	37	10	skin	skin	NOUN
dpc-1620	37	11	biopsy	biopsy	NOUN
dpc-1620	37	12	,	,	PUNCT
dpc-1620	37	13	it	it	PRON
dpc-1620	37	14	has	have	AUX
dpc-1620	37	15	also	also	ADV
dpc-1620	37	16	been	be	AUX
dpc-1620	37	17	applied	apply	VERB
dpc-1620	37	18	to	to	ADP
dpc-1620	37	19	the	the	DET
dpc-1620	37	20	investigation	investigation	NOUN
dpc-1620	37	21	of	of	ADP
dpc-1620	37	22	skin	skin	NOUN
dpc-1620	37	23	aging	age	VERB
dpc-1620	37	24	signs	sign	NOUN
dpc-1620	37	25	[	[	X
dpc-1620	37	26	13	13	NUM
dpc-1620	37	27	]	]	PUNCT
dpc-1620	37	28	.	.	PUNCT
dpc-1620	38	1	this	this	DET
dpc-1620	38	2	article	article	NOUN
dpc-1620	38	3	reviews	review	VERB
dpc-1620	38	4	current	current	ADJ
dpc-1620	38	5	knowledge	knowledge	NOUN
dpc-1620	38	6	about	about	ADP
dpc-1620	38	7	the	the	DET
dpc-1620	38	8	use	use	NOUN
dpc-1620	38	9	of	of	ADP
dpc-1620	38	10	rcm	rcm	PROPN
dpc-1620	38	11	to	to	PART
dpc-1620	38	12	study	study	VERB
dpc-1620	38	13	skin	skin	NOUN
dpc-1620	38	14	aging	aging	NOUN
dpc-1620	38	15	.	.	PUNCT
dpc-1620	39	1	in	in	ADP
dpc-1620	39	2	particular	particular	ADJ
dpc-1620	39	3	,	,	PUNCT
dpc-1620	39	4	basic	basic	ADJ
dpc-1620	39	5	principles	principle	NOUN
dpc-1620	39	6	of	of	ADP
dpc-1620	39	7	the	the	DET
dpc-1620	39	8	technique	technique	NOUN
dpc-1620	39	9	are	be	AUX
dpc-1620	39	10	reviewed	review	VERB
dpc-1620	39	11	and	and	CCONJ
dpc-1620	39	12	the	the	DET
dpc-1620	39	13	rcm	rcm	PROPN
dpc-1620	39	14	features	feature	NOUN
dpc-1620	39	15	of	of	ADP
dpc-1620	39	16	different	different	ADJ
dpc-1620	39	17	skin	skin	NOUN
dpc-1620	39	18	cancers	cancer	NOUN
dpc-1620	39	19	are	be	AUX
dpc-1620	39	20	briefly	briefly	ADV
dpc-1620	39	21	described	describe	VERB
dpc-1620	39	22	.	.	PUNCT
dpc-1620	40	1	basic	basic	ADJ
dpc-1620	40	2	principles	principle	NOUN
dpc-1620	40	3	of	of	ADP
dpc-1620	40	4	rcm	rcm	PROPN
dpc-1620	40	5	technology	technology	PROPN
dpc-1620	40	6	rcm	rcm	PROPN
dpc-1620	40	7	enables	enable	VERB
dpc-1620	40	8	the	the	DET
dpc-1620	40	9	analysis	analysis	NOUN
dpc-1620	40	10	of	of	ADP
dpc-1620	40	11	healthy	healthy	ADJ
dpc-1620	40	12	skin	skin	NOUN
dpc-1620	40	13	compartments	compartment	NOUN
dpc-1620	40	14	by	by	ADP
dpc-1620	40	15	providing	provide	VERB
dpc-1620	40	16	an	an	DET
dpc-1620	40	17	in	in	ADP
dpc-1620	40	18	vivo	vivo	ADJ
dpc-1620	40	19	optical	optical	ADJ
dpc-1620	40	20	biopsy	biopsy	NOUN
dpc-1620	40	21	in	in	ADP
dpc-1620	40	22	a	a	DET
dpc-1620	40	23	totally	totally	ADV
dpc-1620	40	24	noninvasive	noninvasive	ADJ
dpc-1620	40	25	manner	manner	NOUN
dpc-1620	40	26	.	.	PUNCT
dpc-1620	41	1	furthermore	furthermore	ADV
dpc-1620	41	2	,	,	PUNCT
dpc-1620	41	3	rcm	rcm	PROPN
dpc-1620	41	4	can	can	AUX
dpc-1620	41	5	be	be	AUX
dpc-1620	41	6	repeated	repeat	VERB
dpc-1620	41	7	in	in	ADP
dpc-1620	41	8	the	the	DET
dpc-1620	41	9	same	same	ADJ
dpc-1620	41	10	area	area	NOUN
dpc-1620	41	11	at	at	ADP
dpc-1620	41	12	different	different	ADJ
dpc-1620	41	13	times	time	NOUN
dpc-1620	41	14	,	,	PUNCT
dpc-1620	41	15	enabling	enable	VERB
dpc-1620	41	16	the	the	DET
dpc-1620	41	17	assessment	assessment	NOUN
dpc-1620	41	18	of	of	ADP
dpc-1620	41	19	skin	skin	NOUN
dpc-1620	41	20	variations	variation	NOUN
dpc-1620	41	21	,	,	PUNCT
dpc-1620	41	22	such	such	ADJ
dpc-1620	41	23	as	as	ADP
dpc-1620	41	24	during	during	ADP
dpc-1620	41	25	treatment	treatment	NOUN
dpc-1620	41	26	monitoring	monitoring	NOUN
dpc-1620	41	27	.	.	PUNCT
dpc-1620	42	1	a	a	DET
dpc-1620	42	2	reflectance	reflectance	NOUN
dpc-1620	42	3	confocal	confocal	ADJ
dpc-1620	42	4	microscope	microscope	NOUN
dpc-1620	42	5	comprises	comprise	VERB
dpc-1620	42	6	a	a	DET
dpc-1620	42	7	point	point	NOUN
dpc-1620	42	8	source	source	NOUN
dpc-1620	42	9	of	of	ADP
dpc-1620	42	10	light	light	ADJ
dpc-1620	42	11	,	,	PUNCT
dpc-1620	42	12	objective	objective	ADJ
dpc-1620	42	13	lenses	lense	NOUN
dpc-1620	42	14	,	,	PUNCT
dpc-1620	42	15	a	a	DET
dpc-1620	42	16	condenser	condenser	NOUN
dpc-1620	42	17	,	,	PUNCT
dpc-1620	42	18	and	and	CCONJ
dpc-1620	42	19	a	a	DET
dpc-1620	42	20	point	point	NOUN
dpc-1620	42	21	detector	detector	NOUN
dpc-1620	42	22	.	.	PUNCT
dpc-1620	43	1	the	the	DET
dpc-1620	43	2	pinhole	pinhole	NOUN
dpc-1620	43	3	collects	collect	VERB
dpc-1620	43	4	light	light	NOUN
dpc-1620	43	5	from	from	ADP
dpc-1620	43	6	the	the	DET
dpc-1620	43	7	“	"	PUNCT
dpc-1620	43	8	in	in	ADP
dpc-1620	43	9	focus	focus	NOUN
dpc-1620	43	10	”	"	PUNCT
dpc-1620	43	11	plane	plane	NOUN
dpc-1620	43	12	.	.	PUNCT
dpc-1620	44	1	bright	bright	ADJ
dpc-1620	44	2	contrast	contrast	NOUN
dpc-1620	44	3	in	in	ADP
dpc-1620	44	4	rcm	rcm	PROPN
dpc-1620	44	5	is	be	AUX
dpc-1620	44	6	related	relate	VERB
dpc-1620	44	7	to	to	ADP
dpc-1620	44	8	backscattering	backscatter	VERB
dpc-1620	44	9	.	.	PUNCT
dpc-1620	45	1	confocal	confocal	ADJ
dpc-1620	45	2	images	image	NOUN
dpc-1620	45	3	are	be	AUX
dpc-1620	45	4	in	in	ADP
dpc-1620	45	5	grayscale	grayscale	NOUN
dpc-1620	45	6	,	,	PUNCT
dpc-1620	45	7	with	with	ADP
dpc-1620	45	8	bright	bright	ADJ
dpc-1620	45	9	(	(	PUNCT
dpc-1620	45	10	white	white	ADJ
dpc-1620	45	11	)	)	PUNCT
dpc-1620	45	12	structures	structure	NOUN
dpc-1620	45	13	having	have	VERB
dpc-1620	45	14	a	a	DET
dpc-1620	45	15	higher	high	ADJ
dpc-1620	45	16	refractive	refractive	ADJ
dpc-1620	45	17	index	index	NOUN
dpc-1620	45	18	than	than	ADP
dpc-1620	45	19	their	their	PRON
dpc-1620	45	20	surroundings	surrounding	NOUN
dpc-1620	45	21	[	[	X
dpc-1620	45	22	14	14	NUM
dpc-1620	45	23	]	]	PUNCT
dpc-1620	45	24	.	.	PUNCT
dpc-1620	46	1	melanin	melanin	NOUN
dpc-1620	46	2	,	,	PUNCT
dpc-1620	46	3	keratin	keratin	NOUN
dpc-1620	46	4	and	and	CCONJ
dpc-1620	46	5	collagen	collagen	NOUN
dpc-1620	46	6	are	be	AUX
dpc-1620	46	7	examples	example	NOUN
dpc-1620	46	8	of	of	ADP
dpc-1620	46	9	structures	structure	NOUN
dpc-1620	46	10	that	that	PRON
dpc-1620	46	11	appear	appear	VERB
dpc-1620	46	12	bright	bright	ADJ
dpc-1620	46	13	(	(	PUNCT
dpc-1620	46	14	white	white	ADJ
dpc-1620	46	15	)	)	PUNCT
dpc-1620	46	16	.	.	PUNCT
dpc-1620	47	1	technically	technically	ADV
dpc-1620	47	2	,	,	PUNCT
dpc-1620	47	3	rcm	rcm	PROPN
dpc-1620	47	4	has	have	VERB
dpc-1620	47	5	an	an	DET
dpc-1620	47	6	axial	axial	ADJ
dpc-1620	47	7	resolution	resolution	NOUN
dpc-1620	47	8	of	of	ADP
dpc-1620	47	9	3	3	NUM
dpc-1620	47	10	-	-	SYM
dpc-1620	47	11	5	5	NUM
dpc-1620	47	12	μm	μm	NOUN
dpc-1620	47	13	and	and	CCONJ
dpc-1620	47	14	a	a	DET
dpc-1620	47	15	lateral	lateral	ADJ
dpc-1620	47	16	resolution	resolution	NOUN
dpc-1620	47	17	of	of	ADP
dpc-1620	47	18	1	1	NUM
dpc-1620	47	19	μm	μm	NUM
dpc-1620	47	20	,	,	PUNCT
dpc-1620	47	21	and	and	CCONJ
dpc-1620	47	22	it	it	PRON
dpc-1620	47	23	reaches	reach	VERB
dpc-1620	47	24	a	a	DET
dpc-1620	47	25	depth	depth	NOUN
dpc-1620	47	26	of	of	ADP
dpc-1620	47	27	250	250	NUM
dpc-1620	47	28	μm	μm	NUM
dpc-1620	47	29	,	,	PUNCT
dpc-1620	47	30	corresponding	correspond	VERB
dpc-1620	47	31	to	to	ADP
dpc-1620	47	32	the	the	DET
dpc-1620	47	33	upper	upper	ADJ
dpc-1620	47	34	dermis	dermis	NOUN
dpc-1620	47	35	.	.	PUNCT
dpc-1620	48	1	two	two	NUM
dpc-1620	48	2	reflectance	reflectance	NOUN
dpc-1620	48	3	confocal	confocal	ADJ
dpc-1620	48	4	microscopes	microscope	NOUN
dpc-1620	48	5	are	be	AUX
dpc-1620	48	6	commercially	commercially	ADV
dpc-1620	48	7	available	available	ADJ
dpc-1620	48	8	:	:	PUNCT
dpc-1620	48	9	a	a	DET
dpc-1620	48	10	wide	wide	ADJ
dpc-1620	48	11	-	-	PUNCT
dpc-1620	48	12	probe	probe	NOUN
dpc-1620	48	13	microscope	microscope	NOUN
dpc-1620	48	14	(	(	PUNCT
dpc-1620	48	15	vivascope	vivascope	NOUN
dpc-1620	48	16	1500	1500	NUM
dpc-1620	48	17	,	,	PUNCT
dpc-1620	48	18	mavig	mavig	NOUN
dpc-1620	48	19	,	,	PUNCT
dpc-1620	48	20	germany	germany	PROPN
dpc-1620	48	21	)	)	PUNCT
dpc-1620	48	22	and	and	CCONJ
dpc-1620	48	23	a	a	DET
dpc-1620	48	24	handheld	handheld	ADJ
dpc-1620	48	25	model	model	NOUN
dpc-1620	48	26	(	(	PUNCT
dpc-1620	48	27	vivascope	vivascope	NOUN
dpc-1620	48	28	3000	3000	NUM
dpc-1620	48	29	,	,	PUNCT
dpc-1620	48	30	mavig	mavig	NOUN
dpc-1620	48	31	,	,	PUNCT
dpc-1620	48	32	germany	germany	PROPN
dpc-1620	48	33	)	)	PUNCT
dpc-1620	48	34	.	.	PUNCT
dpc-1620	49	1	the	the	DET
dpc-1620	49	2	wide	wide	ADJ
dpc-1620	49	3	-	-	PUNCT
dpc-1620	49	4	probe	probe	NOUN
dpc-1620	49	5	rcm	rcm	PROPN
dpc-1620	49	6	instrument	instrument	NOUN
dpc-1620	49	7	has	have	VERB
dpc-1620	49	8	a	a	DET
dpc-1620	49	9	probe	probe	NOUN
dpc-1620	49	10	that	that	PRON
dpc-1620	49	11	explores	explore	VERB
dpc-1620	49	12	the	the	DET
dpc-1620	49	13	skin	skin	NOUN
dpc-1620	49	14	through	through	ADP
dpc-1620	49	15	a	a	DET
dpc-1620	49	16	disposable	disposable	ADJ
dpc-1620	49	17	plastic	plastic	NOUN
dpc-1620	49	18	window	window	NOUN
dpc-1620	49	19	adherent	adherent	NOUN
dpc-1620	49	20	to	to	ADP
dpc-1620	49	21	a	a	DET
dpc-1620	49	22	metal	metal	NOUN
dpc-1620	49	23	ring	ring	NOUN
dpc-1620	49	24	attached	attach	VERB
dpc-1620	49	25	to	to	ADP
dpc-1620	49	26	the	the	DET
dpc-1620	49	27	skin	skin	NOUN
dpc-1620	49	28	.	.	PUNCT
dpc-1620	50	1	the	the	DET
dpc-1620	50	2	result	result	NOUN
dpc-1620	50	3	is	be	AUX
dpc-1620	50	4	a	a	DET
dpc-1620	50	5	sequence	sequence	NOUN
dpc-1620	50	6	of	of	ADP
dpc-1620	50	7	full	full	ADJ
dpc-1620	50	8	-	-	PUNCT
dpc-1620	50	9	resolution	resolution	NOUN
dpc-1620	50	10	,	,	PUNCT
dpc-1620	50	11	0.5×0.5	0.5×0.5	NUM
dpc-1620	50	12	μm	μm	NUM
dpc-1620	50	13	images	image	NOUN
dpc-1620	50	14	at	at	ADP
dpc-1620	50	15	a	a	DET
dpc-1620	50	16	defined	define	VERB
dpc-1620	50	17	depth	depth	NOUN
dpc-1620	50	18	,	,	PUNCT
dpc-1620	50	19	acquired	acquire	VERB
dpc-1620	50	20	and	and	CCONJ
dpc-1620	50	21	combined	combine	VERB
dpc-1620	50	22	to	to	PART
dpc-1620	50	23	create	create	VERB
dpc-1620	50	24	a	a	DET
dpc-1620	50	25	mosaic	mosaic	ADJ
dpc-1620	50	26	ranging	ranging	NOUN
dpc-1620	50	27	in	in	ADP
dpc-1620	50	28	size	size	NOUN
dpc-1620	50	29	from	from	ADP
dpc-1620	50	30	2×2	2×2	NUM
dpc-1620	50	31	mm	mm	NOUN
dpc-1620	50	32	to	to	ADP
dpc-1620	50	33	8×8	8×8	NUM
dpc-1620	50	34	mm	mm	NOUN
dpc-1620	50	35	.	.	PUNCT
dpc-1620	51	1	when	when	SCONJ
dpc-1620	51	2	inflammatory	inflammatory	ADJ
dpc-1620	51	3	or	or	CCONJ
dpc-1620	51	4	physiologic	physiologic	ADJ
dpc-1620	51	5	skin	skin	NOUN
dpc-1620	51	6	conditions	condition	NOUN
dpc-1620	51	7	are	be	AUX
dpc-1620	51	8	explored	explore	VERB
dpc-1620	51	9	,	,	PUNCT
dpc-1620	51	10	a	a	DET
dpc-1620	51	11	3×3	3×3	NUM
dpc-1620	51	12	mm	mm	NOUN
dpc-1620	51	13	vivacube	vivacube	NOUN
dpc-1620	51	14	,	,	PUNCT
dpc-1620	51	15	composed	compose	VERB
dpc-1620	51	16	of	of	ADP
dpc-1620	51	17	4	4	NUM
dpc-1620	51	18	mosaics	mosaic	NOUN
dpc-1620	51	19	with	with	ADP
dpc-1620	51	20	a	a	DET
dpc-1620	51	21	25	25	NUM
dpc-1620	51	22	-	-	PUNCT
dpc-1620	51	23	μm	μm	NUM
dpc-1620	51	24	step	step	NOUN
dpc-1620	51	25	,	,	PUNCT
dpc-1620	51	26	is	be	AUX
dpc-1620	51	27	collected	collect	VERB
dpc-1620	51	28	and	and	CCONJ
dpc-1620	51	29	analyzed	analyze	VERB
dpc-1620	51	30	.	.	PUNCT
dpc-1620	52	1	in	in	ADP
dpc-1620	52	2	addition	addition	NOUN
dpc-1620	52	3	to	to	ADP
dpc-1620	52	4	horizontal	horizontal	ADJ
dpc-1620	52	5	mosaics	mosaic	NOUN
dpc-1620	52	6	,	,	PUNCT
dpc-1620	52	7	a	a	DET
dpc-1620	52	8	vertical	vertical	ADJ
dpc-1620	52	9	vivastack	vivastack	NOUN
dpc-1620	52	10	can	can	AUX
dpc-1620	52	11	be	be	AUX
dpc-1620	52	12	acquired	acquire	VERB
dpc-1620	52	13	,	,	PUNCT
dpc-1620	52	14	creating	create	VERB
dpc-1620	52	15	an	an	DET
dpc-1620	52	16	optical	optical	ADJ
dpc-1620	52	17	biopsy	biopsy	NOUN
dpc-1620	52	18	consisting	consist	VERB
dpc-1620	52	19	of	of	ADP
dpc-1620	52	20	a	a	DET
dpc-1620	52	21	series	series	NOUN
dpc-1620	52	22	of	of	ADP
dpc-1620	52	23	0.5×0.5	0.5×0.5	NUM
dpc-1620	52	24	high	high	ADJ
dpc-1620	52	25	-	-	PUNCT
dpc-1620	52	26	resolution	resolution	NOUN
dpc-1620	52	27	images	image	NOUN
dpc-1620	52	28	at	at	ADP
dpc-1620	52	29	different	different	ADJ
dpc-1620	52	30	depths	depth	NOUN
dpc-1620	52	31	.	.	PUNCT
dpc-1620	53	1	the	the	DET
dpc-1620	53	2	number	number	NOUN
dpc-1620	53	3	of	of	ADP
dpc-1620	53	4	stacks	stack	NOUN
dpc-1620	53	5	between	between	ADP
dpc-1620	53	6	the	the	DET
dpc-1620	53	7	first	first	ADJ
dpc-1620	53	8	appearance	appearance	NOUN
dpc-1620	53	9	of	of	ADP
dpc-1620	53	10	a	a	DET
dpc-1620	53	11	honeycomb	honeycomb	NOUN
dpc-1620	53	12	pattern	pattern	NOUN
dpc-1620	53	13	and	and	CCONJ
dpc-1620	53	14	the	the	DET
dpc-1620	53	15	first	first	ADJ
dpc-1620	53	16	appearance	appearance	NOUN
dpc-1620	53	17	of	of	ADP
dpc-1620	53	18	collagen	collagen	NOUN
dpc-1620	53	19	,	,	PUNCT
dpc-1620	53	20	with	with	ADP
dpc-1620	53	21	a	a	DET
dpc-1620	53	22	given	give	VERB
dpc-1620	53	23	depth	depth	NOUN
dpc-1620	53	24	,	,	PUNCT
dpc-1620	53	25	is	be	AUX
dpc-1620	53	26	used	use	VERB
dpc-1620	53	27	to	to	PART
dpc-1620	53	28	assess	assess	VERB
dpc-1620	53	29	epidermal	epidermal	ADJ
dpc-1620	53	30	thickness	thickness	NOUN
dpc-1620	54	1	[	[	X
dpc-1620	54	2	13	13	NUM
dpc-1620	54	3	]	]	PUNCT
dpc-1620	54	4	.	.	PUNCT
dpc-1620	55	1	the	the	DET
dpc-1620	55	2	handheld	handheld	ADJ
dpc-1620	55	3	rcm	rcm	PROPN
dpc-1620	55	4	model	model	NOUN
dpc-1620	55	5	is	be	AUX
dpc-1620	55	6	a	a	DET
dpc-1620	55	7	smaller	small	ADJ
dpc-1620	55	8	,	,	PUNCT
dpc-1620	55	9	flexible	flexible	ADJ
dpc-1620	55	10	device	device	NOUN
dpc-1620	55	11	that	that	PRON
dpc-1620	55	12	permits	permit	VERB
dpc-1620	55	13	the	the	DET
dpc-1620	55	14	exploration	exploration	NOUN
dpc-1620	55	15	of	of	ADP
dpc-1620	55	16	difficult	difficult	ADJ
dpc-1620	55	17	-	-	PUNCT
dpc-1620	55	18	to	to	ADP
dpc-1620	55	19	-	-	PUNCT
dpc-1620	55	20	access	access	NOUN
dpc-1620	55	21	areas	area	NOUN
dpc-1620	55	22	,	,	PUNCT
dpc-1620	55	23	such	such	ADJ
dpc-1620	55	24	as	as	ADP
dpc-1620	55	25	ears	ear	NOUN
dpc-1620	55	26	and	and	CCONJ
dpc-1620	55	27	skin	skin	NOUN
dpc-1620	55	28	folds	fold	NOUN
dpc-1620	55	29	.	.	PUNCT
dpc-1620	56	1	however	however	ADV
dpc-1620	56	2	,	,	PUNCT
dpc-1620	56	3	the	the	DET
dpc-1620	56	4	handheld	handheld	ADJ
dpc-1620	56	5	tool	tool	NOUN
dpc-1620	56	6	does	do	AUX
dpc-1620	56	7	not	not	PART
dpc-1620	56	8	allow	allow	VERB
dpc-1620	56	9	visualization	visualization	NOUN
dpc-1620	56	10	of	of	ADP
dpc-1620	56	11	a	a	DET
dpc-1620	56	12	large	large	ADJ
dpc-1620	56	13	field	field	NOUN
dpc-1620	56	14	of	of	ADP
dpc-1620	56	15	view	view	NOUN
dpc-1620	56	16	.	.	PUNCT
dpc-1620	57	1	only	only	ADV
dpc-1620	57	2	single	single	ADJ
dpc-1620	57	3	0.5×0.5	0.5×0.5	NUM
dpc-1620	57	4	mm	mm	NOUN
dpc-1620	57	5	images	image	NOUN
dpc-1620	57	6	and	and	CCONJ
dpc-1620	57	7	vivastacks	vivastack	NOUN
dpc-1620	57	8	can	can	AUX
dpc-1620	57	9	be	be	AUX
dpc-1620	57	10	acquired	acquire	VERB
dpc-1620	57	11	.	.	PUNCT
dpc-1620	58	1	the	the	DET
dpc-1620	58	2	view	view	NOUN
dpc-1620	58	3	of	of	ADP
dpc-1620	58	4	larger	large	ADJ
dpc-1620	58	5	fields	field	NOUN
dpc-1620	58	6	is	be	AUX
dpc-1620	58	7	impaired	impair	VERB
dpc-1620	58	8	[	[	X
dpc-1620	58	9	1,13	1,13	NUM
dpc-1620	58	10	]	]	PUNCT
dpc-1620	58	11	.	.	PUNCT
dpc-1620	59	1	skin	skin	NOUN
dpc-1620	59	2	morphology	morphology	NOUN
dpc-1620	59	3	over	over	ADP
dpc-1620	59	4	the	the	DET
dpc-1620	59	5	years	year	NOUN
dpc-1620	59	6	skin	skin	NOUN
dpc-1620	59	7	aging	aging	NOUN
dpc-1620	59	8	involves	involve	VERB
dpc-1620	59	9	variations	variation	NOUN
dpc-1620	59	10	at	at	ADP
dpc-1620	59	11	both	both	CCONJ
dpc-1620	59	12	the	the	DET
dpc-1620	59	13	epidermal	epidermal	ADJ
dpc-1620	59	14	and	and	CCONJ
dpc-1620	59	15	dermal	dermal	ADJ
dpc-1620	59	16	levels	level	NOUN
dpc-1620	59	17	.	.	PUNCT
dpc-1620	60	1	these	these	DET
dpc-1620	60	2	changes	change	NOUN
dpc-1620	60	3	can	can	AUX
dpc-1620	60	4	be	be	AUX
dpc-1620	60	5	noninvasively	noninvasively	ADV
dpc-1620	60	6	detected	detect	VERB
dpc-1620	60	7	with	with	ADP
dpc-1620	60	8	rcm	rcm	PROPN
dpc-1620	60	9	.	.	PUNCT
dpc-1620	61	1	to	to	PART
dpc-1620	61	2	detect	detect	VERB
dpc-1620	61	3	skin	skin	NOUN
dpc-1620	61	4	variations	variation	NOUN
dpc-1620	61	5	that	that	PRON
dpc-1620	61	6	occur	occur	VERB
dpc-1620	61	7	with	with	ADP
dpc-1620	61	8	passing	pass	VERB
dpc-1620	61	9	time	time	NOUN
dpc-1620	61	10	,	,	PUNCT
dpc-1620	61	11	it	it	PRON
dpc-1620	61	12	is	be	AUX
dpc-1620	61	13	important	important	ADJ
dpc-1620	61	14	to	to	PART
dpc-1620	61	15	understand	understand	VERB
dpc-1620	61	16	the	the	DET
dpc-1620	61	17	morphology	morphology	NOUN
dpc-1620	61	18	of	of	ADP
dpc-1620	61	19	healthy	healthy	ADJ
dpc-1620	61	20	skin	skin	NOUN
dpc-1620	61	21	as	as	SCONJ
dpc-1620	61	22	it	it	PRON
dpc-1620	61	23	progressively	progressively	ADV
dpc-1620	61	24	changes	change	VERB
dpc-1620	61	25	from	from	ADP
dpc-1620	61	26	young	young	ADJ
dpc-1620	61	27	skin	skin	NOUN
dpc-1620	61	28	to	to	ADP
dpc-1620	61	29	elderly	elderly	ADJ
dpc-1620	61	30	skin	skin	NOUN
dpc-1620	61	31	[	[	X
dpc-1620	61	32	1,13,15	1,13,15	NUM
dpc-1620	61	33	-	-	SYM
dpc-1620	61	34	23	23	NUM
dpc-1620	61	35	]	]	PUNCT
dpc-1620	61	36	.	.	PUNCT
dpc-1620	62	1	healthy	healthy	ADJ
dpc-1620	62	2	young	young	ADJ
dpc-1620	62	3	skin	skin	NOUN
dpc-1620	62	4	rcm	rcm	PROPN
dpc-1620	62	5	can	can	AUX
dpc-1620	62	6	be	be	AUX
dpc-1620	62	7	used	use	VERB
dpc-1620	62	8	to	to	PART
dpc-1620	62	9	evaluate	evaluate	VERB
dpc-1620	62	10	the	the	DET
dpc-1620	62	11	epidermis	epidermis	NOUN
dpc-1620	62	12	,	,	PUNCT
dpc-1620	62	13	the	the	DET
dpc-1620	62	14	dermo	dermo	NOUN
dpc-1620	62	15	-	-	PUNCT
dpc-1620	62	16	epidermal	epidermal	ADJ
dpc-1620	62	17	junction	junction	NOUN
dpc-1620	62	18	(	(	PUNCT
dpc-1620	62	19	dej	dej	PROPN
dpc-1620	62	20	)	)	PUNCT
dpc-1620	62	21	and	and	CCONJ
dpc-1620	62	22	the	the	DET
dpc-1620	62	23	upper	upper	ADJ
dpc-1620	62	24	dermis	dermis	NOUN
dpc-1620	62	25	(	(	PUNCT
dpc-1620	62	26	table	table	NOUN
dpc-1620	62	27	1	1	NUM
dpc-1620	62	28	)	)	PUNCT
dpc-1620	62	29	.	.	PUNCT
dpc-1620	63	1	when	when	SCONJ
dpc-1620	63	2	analyzing	analyze	VERB
dpc-1620	63	3	the	the	DET
dpc-1620	63	4	epidermis	epidermis	NOUN
dpc-1620	63	5	,	,	PUNCT
dpc-1620	63	6	the	the	DET
dpc-1620	63	7	microscopist	microscopist	NOUN
dpc-1620	63	8	first	first	ADV
dpc-1620	63	9	sees	see	VERB
dpc-1620	63	10	the	the	DET
dpc-1620	63	11	stratum	stratum	NOUN
dpc-1620	63	12	corneum	corneum	VERB
dpc-1620	63	13	at	at	ADP
dpc-1620	63	14	the	the	DET
dpc-1620	63	15	top	top	ADJ
dpc-1620	63	16	surface	surface	NOUN
dpc-1620	63	17	.	.	PUNCT
dpc-1620	64	1	this	this	DET
dpc-1620	64	2	skin	skin	NOUN
dpc-1620	64	3	layer	layer	NOUN
dpc-1620	64	4	is	be	AUX
dpc-1620	64	5	characterized	characterize	VERB
dpc-1620	64	6	by	by	ADP
dpc-1620	64	7	the	the	DET
dpc-1620	64	8	presence	presence	NOUN
dpc-1620	64	9	of	of	ADP
dpc-1620	64	10	large	large	ADJ
dpc-1620	64	11	,	,	PUNCT
dpc-1620	64	12	bright	bright	ADJ
dpc-1620	64	13	,	,	PUNCT
dpc-1620	64	14	anucleated	anucleate	VERB
dpc-1620	64	15	cells	cell	NOUN
dpc-1620	64	16	(	(	PUNCT
dpc-1620	64	17	corneocytes	corneocyte	NOUN
dpc-1620	64	18	)	)	PUNCT
dpc-1620	64	19	that	that	PRON
dpc-1620	64	20	are	be	AUX
dpc-1620	64	21	polygonal	polygonal	ADJ
dpc-1620	64	22	,	,	PUNCT
dpc-1620	64	23	10–30	10–30	NUM
dpc-1620	64	24	mm	mm	NOUN
dpc-1620	64	25	in	in	ADP
dpc-1620	64	26	size	size	NOUN
dpc-1620	64	27	,	,	PUNCT
dpc-1620	64	28	and	and	CCONJ
dpc-1620	64	29	have	have	VERB
dpc-1620	64	30	the	the	DET
dpc-1620	64	31	tendency	tendency	NOUN
dpc-1620	64	32	to	to	PART
dpc-1620	64	33	form	form	VERB
dpc-1620	64	34	‘	'	PUNCT
dpc-1620	64	35	‘	'	PUNCT
dpc-1620	64	36	islands	island	NOUN
dpc-1620	64	37	’’	’'	PUNCT
dpc-1620	64	38	surrounded	surround	VERB
dpc-1620	64	39	by	by	ADP
dpc-1620	64	40	dark	dark	ADJ
dpc-1620	64	41	areas	area	NOUN
dpc-1620	64	42	,	,	PUNCT
dpc-1620	64	43	corresponding	correspond	VERB
dpc-1620	64	44	to	to	ADP
dpc-1620	64	45	skin	skin	NOUN
dpc-1620	64	46	furrows	furrow	NOUN
dpc-1620	64	47	[	[	X
dpc-1620	64	48	24	24	NUM
dpc-1620	64	49	]	]	PUNCT
dpc-1620	64	50	.	.	PUNCT
dpc-1620	65	1	going	go	VERB
dpc-1620	65	2	deeper	deeply	ADV
dpc-1620	65	3	to	to	ADP
dpc-1620	65	4	the	the	DET
dpc-1620	65	5	granulosum	granulosum	NOUN
dpc-1620	65	6	-	-	PUNCT
dpc-1620	65	7	spinosum	spinosum	NOUN
dpc-1620	65	8	layer	layer	NOUN
dpc-1620	65	9	,	,	PUNCT
dpc-1620	65	10	keratinocytes	keratinocyte	NOUN
dpc-1620	65	11	are	be	AUX
dpc-1620	65	12	characterized	characterize	VERB
dpc-1620	65	13	by	by	ADP
dpc-1620	65	14	dark	dark	ADJ
dpc-1620	65	15	nuclei	nucleus	NOUN
dpc-1620	65	16	and	and	CCONJ
dpc-1620	65	17	bright	bright	ADJ
dpc-1620	65	18	cytoplasm	cytoplasm	NOUN
dpc-1620	65	19	.	.	PUNCT
dpc-1620	66	1	in	in	ADP
dpc-1620	66	2	particular	particular	ADJ
dpc-1620	66	3	,	,	PUNCT
dpc-1620	66	4	a	a	DET
dpc-1620	66	5	grainy	grainy	ADJ
dpc-1620	66	6	appearance	appearance	NOUN
dpc-1620	66	7	is	be	AUX
dpc-1620	66	8	typically	typically	ADV
dpc-1620	66	9	observed	observe	VERB
dpc-1620	66	10	in	in	ADP
dpc-1620	66	11	cells	cell	NOUN
dpc-1620	66	12	of	of	ADP
dpc-1620	66	13	the	the	DET
dpc-1620	66	14	granulosum	granulosum	NOUN
dpc-1620	66	15	layer	layer	NOUN
dpc-1620	66	16	,	,	PUNCT
dpc-1620	66	17	due	due	ADP
dpc-1620	66	18	to	to	ADP
dpc-1620	66	19	the	the	DET
dpc-1620	66	20	presence	presence	NOUN
dpc-1620	66	21	of	of	ADP
dpc-1620	66	22	organelles	organelle	NOUN
dpc-1620	66	23	.	.	PUNCT
dpc-1620	67	1	the	the	DET
dpc-1620	67	2	organization	organization	NOUN
dpc-1620	67	3	of	of	ADP
dpc-1620	67	4	keratinocytes	keratinocyte	NOUN
dpc-1620	67	5	is	be	AUX
dpc-1620	67	6	similar	similar	ADJ
dpc-1620	67	7	to	to	ADP
dpc-1620	67	8	a	a	DET
dpc-1620	67	9	honeycomb	honeycomb	NOUN
dpc-1620	67	10	.	.	PUNCT
dpc-1620	68	1	therefore	therefore	ADV
dpc-1620	68	2	,	,	PUNCT
dpc-1620	68	3	the	the	DET
dpc-1620	68	4	typically	typically	ADV
dpc-1620	68	5	observed	observe	VERB
dpc-1620	68	6	pattern	pattern	NOUN
dpc-1620	68	7	at	at	ADP
dpc-1620	68	8	the	the	DET
dpc-1620	68	9	epidermal	epidermal	ADJ
dpc-1620	68	10	level	level	NOUN
dpc-1620	68	11	in	in	ADP
dpc-1620	68	12	people	people	NOUN
dpc-1620	68	13	with	with	ADP
dpc-1620	68	14	light	light	ADJ
dpc-1620	68	15	skin	skin	NOUN
dpc-1620	68	16	is	be	AUX
dpc-1620	68	17	called	call	VERB
dpc-1620	68	18	honeycomb	honeycomb	NOUN
dpc-1620	68	19	pattern	pattern	NOUN
dpc-1620	68	20	(	(	PUNCT
dpc-1620	68	21	figure	figure	NOUN
dpc-1620	68	22	1a	1a	NOUN
dpc-1620	68	23	)	)	PUNCT
dpc-1620	69	1	[	[	X
dpc-1620	69	2	24	24	NUM
dpc-1620	69	3	]	]	PUNCT
dpc-1620	69	4	.	.	PUNCT
dpc-1620	70	1	in	in	ADP
dpc-1620	70	2	light	light	ADJ
dpc-1620	70	3	-	-	PUNCT
dpc-1620	70	4	skinned	skinned	ADJ
dpc-1620	70	5	people	people	NOUN
dpc-1620	70	6	,	,	PUNCT
dpc-1620	70	7	the	the	DET
dpc-1620	70	8	keratinocyte	keratinocyte	NOUN
dpc-1620	70	9	contour	contour	NOUN
dpc-1620	70	10	is	be	AUX
dpc-1620	70	11	brighter	bright	ADJ
dpc-1620	70	12	than	than	ADP
dpc-1620	70	13	the	the	DET
dpc-1620	70	14	cytoplasm	cytoplasm	NOUN
dpc-1620	70	15	.	.	PUNCT
dpc-1620	71	1	conversely	conversely	ADV
dpc-1620	71	2	,	,	PUNCT
dpc-1620	71	3	people	people	NOUN
dpc-1620	71	4	with	with	ADP
dpc-1620	71	5	dark	dark	ADJ
dpc-1620	71	6	skin	skin	NOUN
dpc-1620	71	7	show	show	VERB
dpc-1620	71	8	a	a	DET
dpc-1620	71	9	different	different	ADJ
dpc-1620	71	10	pattern	pattern	NOUN
dpc-1620	71	11	,	,	PUNCT
dpc-1620	71	12	called	call	VERB
dpc-1620	71	13	cobblestone	cobblestone	NOUN
dpc-1620	71	14	pattern	pattern	NOUN
dpc-1620	71	15	,	,	PUNCT
dpc-1620	71	16	that	that	PRON
dpc-1620	71	17	is	be	AUX
dpc-1620	71	18	the	the	DET
dpc-1620	71	19	negative	negative	ADJ
dpc-1620	71	20	of	of	ADP
dpc-1620	71	21	a	a	DET
dpc-1620	71	22	honeycomb	honeycomb	NOUN
dpc-1620	71	23	pattern	pattern	NOUN
dpc-1620	71	24	,	,	PUNCT
dpc-1620	71	25	with	with	ADP
dpc-1620	71	26	pigmented	pigmented	ADJ
dpc-1620	71	27	(	(	PUNCT
dpc-1620	71	28	bright	bright	ADJ
dpc-1620	71	29	)	)	PUNCT
dpc-1620	71	30	keratinocytes	keratinocyte	NOUN
dpc-1620	71	31	separated	separate	VERB
dpc-1620	71	32	by	by	ADP
dpc-1620	71	33	a	a	DET
dpc-1620	71	34	dark	dark	ADJ
dpc-1620	71	35	contour	contour	NOUN
dpc-1620	72	1	[	[	X
dpc-1620	72	2	16	16	NUM
dpc-1620	72	3	]	]	PUNCT
dpc-1620	72	4	.	.	PUNCT
dpc-1620	73	1	going	go	VERB
dpc-1620	73	2	to	to	ADP
dpc-1620	73	3	the	the	DET
dpc-1620	73	4	basal	basal	ADJ
dpc-1620	73	5	layer	layer	NOUN
dpc-1620	73	6	of	of	ADP
dpc-1620	73	7	the	the	DET
dpc-1620	73	8	epidermis	epidermis	NOUN
dpc-1620	73	9	,	,	PUNCT
dpc-1620	73	10	basal	basal	ADJ
dpc-1620	73	11	cells	cell	NOUN
dpc-1620	73	12	appear	appear	VERB
dpc-1620	73	13	as	as	ADP
dpc-1620	73	14	cells	cell	NOUN
dpc-1620	73	15	of	of	ADP
dpc-1620	73	16	the	the	DET
dpc-1620	73	17	same	same	ADJ
dpc-1620	73	18	size	size	NOUN
dpc-1620	73	19	(	(	PUNCT
dpc-1620	73	20	7–12	7–12	PROPN
dpc-1620	73	21	mm	mm	NOUN
dpc-1620	73	22	)	)	PUNCT
dpc-1620	73	23	and	and	CCONJ
dpc-1620	73	24	shape	shape	VERB
dpc-1620	73	25	although	although	SCONJ
dpc-1620	73	26	they	they	PRON
dpc-1620	73	27	are	be	AUX
dpc-1620	73	28	smaller	small	ADJ
dpc-1620	73	29	than	than	ADP
dpc-1620	73	30	the	the	DET
dpc-1620	73	31	keratinocytes	keratinocyte	NOUN
dpc-1620	73	32	of	of	ADP
dpc-1620	73	33	the	the	DET
dpc-1620	73	34	upper	upper	ADJ
dpc-1620	73	35	layers	layer	NOUN
dpc-1620	73	36	and	and	CCONJ
dpc-1620	73	37	have	have	VERB
dpc-1620	73	38	high	high	ADJ
dpc-1620	73	39	refractivity	refractivity	NOUN
dpc-1620	73	40	due	due	ADP
dpc-1620	73	41	to	to	ADP
dpc-1620	73	42	their	their	PRON
dpc-1620	73	43	melanin	melanin	NOUN
dpc-1620	73	44	content	content	NOUN
dpc-1620	73	45	[	[	X
dpc-1620	73	46	14	14	NUM
dpc-1620	73	47	]	]	PUNCT
dpc-1620	73	48	.	.	PUNCT
dpc-1620	74	1	review	review	VERB
dpc-1620	74	2	|	|	ADV
dpc-1620	74	3	dermatol	dermatol	ADJ
dpc-1620	74	4	pract	pract	NOUN
dpc-1620	74	5	concept	concept	NOUN
dpc-1620	74	6	.	.	PUNCT
dpc-1620	75	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	75	2	2021068	2021068	NUM
dpc-1620	75	3	3	3	NUM
dpc-1620	75	4	the	the	DET
dpc-1620	75	5	epidermal	epidermal	ADJ
dpc-1620	75	6	thickness	thickness	NOUN
dpc-1620	75	7	can	can	AUX
dpc-1620	75	8	be	be	AUX
dpc-1620	75	9	estimated	estimate	VERB
dpc-1620	75	10	from	from	ADP
dpc-1620	75	11	the	the	DET
dpc-1620	75	12	number	number	NOUN
dpc-1620	75	13	of	of	ADP
dpc-1620	75	14	stacks	stack	NOUN
dpc-1620	75	15	from	from	ADP
dpc-1620	75	16	the	the	DET
dpc-1620	75	17	visualization	visualization	NOUN
dpc-1620	75	18	of	of	ADP
dpc-1620	75	19	the	the	DET
dpc-1620	75	20	honeycomb	honeycomb	NOUN
dpc-1620	75	21	pattern	pattern	NOUN
dpc-1620	75	22	to	to	ADP
dpc-1620	75	23	the	the	DET
dpc-1620	75	24	observation	observation	NOUN
dpc-1620	75	25	of	of	ADP
dpc-1620	75	26	collagen	collagen	NOUN
dpc-1620	75	27	[	[	X
dpc-1620	75	28	13	13	NUM
dpc-1620	75	29	]	]	PUNCT
dpc-1620	75	30	.	.	PUNCT
dpc-1620	76	1	interestingly	interestingly	ADV
dpc-1620	76	2	,	,	PUNCT
dpc-1620	76	3	melanocytes	melanocyte	NOUN
dpc-1620	76	4	are	be	AUX
dpc-1620	76	5	not	not	PART
dpc-1620	76	6	recognized	recognize	VERB
dpc-1620	76	7	in	in	ADP
dpc-1620	76	8	healthy	healthy	ADJ
dpc-1620	76	9	skin	skin	NOUN
dpc-1620	76	10	because	because	SCONJ
dpc-1620	76	11	they	they	PRON
dpc-1620	76	12	share	share	VERB
dpc-1620	76	13	features	feature	NOUN
dpc-1620	76	14	with	with	ADP
dpc-1620	76	15	keratinocytes	keratinocyte	NOUN
dpc-1620	76	16	in	in	ADP
dpc-1620	76	17	terms	term	NOUN
dpc-1620	76	18	of	of	ADP
dpc-1620	76	19	size	size	NOUN
dpc-1620	76	20	and	and	CCONJ
dpc-1620	76	21	amount	amount	NOUN
dpc-1620	76	22	of	of	ADP
dpc-1620	76	23	melanin	melanin	NOUN
dpc-1620	76	24	[	[	X
dpc-1620	76	25	14	14	NUM
dpc-1620	76	26	]	]	PUNCT
dpc-1620	76	27	.	.	PUNCT
dpc-1620	77	1	at	at	ADP
dpc-1620	77	2	the	the	DET
dpc-1620	77	3	dej	dej	PROPN
dpc-1620	77	4	level	level	NOUN
dpc-1620	77	5	,	,	PUNCT
dpc-1620	77	6	basal	basal	ADJ
dpc-1620	77	7	cells	cell	NOUN
dpc-1620	77	8	tend	tend	VERB
dpc-1620	77	9	to	to	PART
dpc-1620	77	10	form	form	VERB
dpc-1620	77	11	oval	oval	NOUN
dpc-1620	77	12	or	or	CCONJ
dpc-1620	77	13	round	round	ADJ
dpc-1620	77	14	bright	bright	ADJ
dpc-1620	77	15	rings	ring	NOUN
dpc-1620	77	16	centered	center	VERB
dpc-1620	77	17	by	by	ADP
dpc-1620	77	18	dark	dark	ADJ
dpc-1620	77	19	dermal	dermal	NOUN
dpc-1620	77	20	papillae	papillae	NOUN
dpc-1620	77	21	,	,	PUNCT
dpc-1620	77	22	defining	define	VERB
dpc-1620	77	23	the	the	DET
dpc-1620	77	24	so	so	ADV
dpc-1620	77	25	-	-	PUNCT
dpc-1620	77	26	called	call	VERB
dpc-1620	77	27	ring	ring	NOUN
dpc-1620	77	28	pattern	pattern	NOUN
dpc-1620	77	29	[	[	X
dpc-1620	77	30	14	14	NUM
dpc-1620	77	31	]	]	PUNCT
dpc-1620	77	32	.	.	PUNCT
dpc-1620	78	1	intuitively	intuitively	ADV
dpc-1620	78	2	,	,	PUNCT
dpc-1620	78	3	melanin	melanin	NOUN
dpc-1620	78	4	content	content	NOUN
dpc-1620	78	5	and	and	CCONJ
dpc-1620	78	6	skin	skin	NOUN
dpc-1620	78	7	phototype	phototype	NOUN
dpc-1620	78	8	influence	influence	VERB
dpc-1620	78	9	the	the	DET
dpc-1620	78	10	brightness	brightness	NOUN
dpc-1620	78	11	of	of	ADP
dpc-1620	78	12	keratinocytes	keratinocyte	NOUN
dpc-1620	78	13	:	:	PUNCT
dpc-1620	78	14	the	the	DET
dpc-1620	78	15	darker	dark	ADJ
dpc-1620	78	16	the	the	DET
dpc-1620	78	17	skin	skin	NOUN
dpc-1620	78	18	phototype	phototype	NOUN
dpc-1620	78	19	,	,	PUNCT
dpc-1620	78	20	the	the	PRON
dpc-1620	78	21	brighter	bright	ADJ
dpc-1620	78	22	the	the	DET
dpc-1620	78	23	basal	basal	ADJ
dpc-1620	78	24	cells	cell	NOUN
dpc-1620	78	25	and	and	CCONJ
dpc-1620	78	26	rings	ring	NOUN
dpc-1620	78	27	appear	appear	VERB
dpc-1620	78	28	.	.	PUNCT
dpc-1620	79	1	however	however	ADV
dpc-1620	79	2	,	,	PUNCT
dpc-1620	79	3	on	on	ADP
dpc-1620	79	4	the	the	DET
dpc-1620	79	5	face	face	NOUN
dpc-1620	79	6	,	,	PUNCT
dpc-1620	79	7	rings	ring	NOUN
dpc-1620	79	8	can	can	AUX
dpc-1620	79	9	not	not	PART
dpc-1620	79	10	be	be	AUX
dpc-1620	79	11	visualized	visualize	VERB
dpc-1620	79	12	[	[	PUNCT
dpc-1620	79	13	16	16	NUM
dpc-1620	79	14	]	]	PUNCT
dpc-1620	79	15	.	.	PUNCT
dpc-1620	80	1	in	in	ADP
dpc-1620	80	2	young	young	ADJ
dpc-1620	80	3	subjects	subject	NOUN
dpc-1620	80	4	,	,	PUNCT
dpc-1620	80	5	the	the	DET
dpc-1620	80	6	dermis	dermis	NOUN
dpc-1620	80	7	is	be	AUX
dpc-1620	80	8	mainly	mainly	ADV
dpc-1620	80	9	composed	compose	VERB
dpc-1620	80	10	of	of	ADP
dpc-1620	80	11	thin	thin	ADJ
dpc-1620	80	12	,	,	PUNCT
dpc-1620	80	13	hyper	hyper	ADJ
dpc-1620	80	14	-	-	ADJ
dpc-1620	80	15	reflective	reflective	ADJ
dpc-1620	80	16	reticulated	reticulated	ADJ
dpc-1620	80	17	fibers	fiber	NOUN
dpc-1620	80	18	,	,	PUNCT
dpc-1620	80	19	with	with	ADP
dpc-1620	80	20	a	a	DET
dpc-1620	80	21	weblike	weblike	NOUN
dpc-1620	80	22	organization	organization	NOUN
dpc-1620	80	23	(	(	PUNCT
dpc-1620	80	24	figure	figure	NOUN
dpc-1620	80	25	1b	1b	NUM
dpc-1620	80	26	)	)	PUNCT
dpc-1620	81	1	[	[	X
dpc-1620	81	2	16	16	NUM
dpc-1620	81	3	]	]	PUNCT
dpc-1620	81	4	.	.	PUNCT
dpc-1620	82	1	other	other	ADJ
dpc-1620	82	2	structures	structure	NOUN
dpc-1620	82	3	that	that	PRON
dpc-1620	82	4	are	be	AUX
dpc-1620	82	5	visualized	visualize	VERB
dpc-1620	82	6	are	be	AUX
dpc-1620	82	7	the	the	DET
dpc-1620	82	8	sebaceous	sebaceous	ADJ
dpc-1620	82	9	glands	gland	NOUN
dpc-1620	82	10	,	,	PUNCT
dpc-1620	82	11	corresponding	correspond	VERB
dpc-1620	82	12	to	to	ADP
dpc-1620	82	13	hair	hair	NOUN
dpc-1620	82	14	shafts	shafts	ADJ
dpc-1620	82	15	within	within	ADP
dpc-1620	82	16	hair	hair	NOUN
dpc-1620	82	17	follicles	follicle	NOUN
dpc-1620	82	18	,	,	PUNCT
dpc-1620	82	19	and	and	CCONJ
dpc-1620	82	20	sweat	sweat	NOUN
dpc-1620	82	21	ducts	duct	NOUN
dpc-1620	82	22	located	locate	VERB
dpc-1620	82	23	in	in	ADP
dpc-1620	82	24	the	the	DET
dpc-1620	82	25	dermis	dermis	NOUN
dpc-1620	82	26	.	.	PUNCT
dpc-1620	83	1	the	the	DET
dpc-1620	83	2	face	face	NOUN
dpc-1620	83	3	is	be	AUX
dpc-1620	83	4	characterized	characterize	VERB
dpc-1620	83	5	by	by	ADP
dpc-1620	83	6	several	several	ADJ
dpc-1620	83	7	hair	hair	NOUN
dpc-1620	83	8	follicles	follicle	NOUN
dpc-1620	83	9	creating	create	VERB
dpc-1620	83	10	dark	dark	ADJ
dpc-1620	83	11	round	round	NOUN
dpc-1620	83	12	areas	area	NOUN
dpc-1620	83	13	centered	center	VERB
dpc-1620	83	14	by	by	ADP
dpc-1620	83	15	a	a	DET
dpc-1620	83	16	hair	hair	NOUN
dpc-1620	83	17	shaft	shaft	NOUN
dpc-1620	84	1	[	[	X
dpc-1620	84	2	16	16	NUM
dpc-1620	84	3	]	]	PUNCT
dpc-1620	84	4	.	.	PUNCT
dpc-1620	85	1	table	table	NOUN
dpc-1620	85	2	1	1	NUM
dpc-1620	85	3	.	.	PUNCT
dpc-1620	86	1	features	feature	NOUN
dpc-1620	86	2	of	of	ADP
dpc-1620	86	3	skin	skin	NOUN
dpc-1620	86	4	seen	see	VERB
dpc-1620	86	5	with	with	ADP
dpc-1620	86	6	reflectance	reflectance	NOUN
dpc-1620	86	7	confocal	confocal	ADJ
dpc-1620	86	8	microscopy	microscopy	NOUN
dpc-1620	86	9	feature	feature	NOUN
dpc-1620	86	10	description	description	NOUN
dpc-1620	86	11	epidermis	epidermis	ADP
dpc-1620	86	12	regular	regular	ADJ
dpc-1620	86	13	honeycomb	honeycomb	NOUN
dpc-1620	86	14	pattern	pattern	NOUN
dpc-1620	86	15	polygonal	polygonal	ADJ
dpc-1620	86	16	keratinocytes	keratinocyte	NOUN
dpc-1620	86	17	of	of	ADP
dpc-1620	86	18	uniform	uniform	ADJ
dpc-1620	86	19	size	size	NOUN
dpc-1620	86	20	and	and	CCONJ
dpc-1620	86	21	shape	shape	NOUN
dpc-1620	86	22	,	,	PUNCT
dpc-1620	86	23	with	with	ADP
dpc-1620	86	24	well	well	ADV
dpc-1620	86	25	-	-	PUNCT
dpc-1620	86	26	defined	define	VERB
dpc-1620	86	27	borders	border	NOUN
dpc-1620	86	28	irregular	irregular	ADJ
dpc-1620	86	29	honeycomb	honeycomb	NOUN
dpc-1620	86	30	pattern	pattern	NOUN
dpc-1620	86	31	keratinocytes	keratinocyte	NOUN
dpc-1620	86	32	of	of	ADP
dpc-1620	86	33	variable	variable	ADJ
dpc-1620	86	34	size	size	NOUN
dpc-1620	86	35	and	and	CCONJ
dpc-1620	86	36	shape	shape	NOUN
dpc-1620	86	37	and	and	CCONJ
dpc-1620	86	38	ill	ill	ADV
dpc-1620	86	39	-	-	PUNCT
dpc-1620	86	40	defined	define	VERB
dpc-1620	86	41	borders	border	NOUN
dpc-1620	86	42	mottled	mottle	VERB
dpc-1620	86	43	pigmentation	pigmentation	NOUN
dpc-1620	86	44	cluster	cluster	NOUN
dpc-1620	86	45	of	of	ADP
dpc-1620	86	46	bright	bright	ADJ
dpc-1620	86	47	keratinocytes	keratinocyte	NOUN
dpc-1620	86	48	within	within	ADP
dpc-1620	86	49	a	a	DET
dpc-1620	86	50	honeycomb	honeycomb	NOUN
dpc-1620	86	51	pattern	pattern	NOUN
dpc-1620	86	52	epidermal	epidermal	ADJ
dpc-1620	86	53	thickness	thickness	NOUN
dpc-1620	86	54	estimated	estimate	VERB
dpc-1620	86	55	from	from	ADP
dpc-1620	86	56	the	the	DET
dpc-1620	86	57	number	number	NOUN
dpc-1620	86	58	of	of	ADP
dpc-1620	86	59	stacks	stack	NOUN
dpc-1620	86	60	(	(	PUNCT
dpc-1620	86	61	starting	start	VERB
dpc-1620	86	62	from	from	ADP
dpc-1620	86	63	the	the	DET
dpc-1620	86	64	first	first	ADJ
dpc-1620	86	65	visualization	visualization	NOUN
dpc-1620	86	66	of	of	ADP
dpc-1620	86	67	the	the	DET
dpc-1620	86	68	honeycomb	honeycomb	NOUN
dpc-1620	86	69	pattern	pattern	NOUN
dpc-1620	86	70	to	to	ADP
dpc-1620	86	71	the	the	DET
dpc-1620	86	72	presence	presence	NOUN
dpc-1620	86	73	of	of	ADP
dpc-1620	86	74	collagen	collagen	NOUN
dpc-1620	86	75	)	)	PUNCT
dpc-1620	86	76	furrow	furrow	NOUN
dpc-1620	86	77	aspects	aspect	NOUN
dpc-1620	86	78	dark	dark	ADJ
dpc-1620	86	79	folds	fold	NOUN
dpc-1620	86	80	between	between	ADP
dpc-1620	86	81	groups	group	NOUN
dpc-1620	86	82	of	of	ADP
dpc-1620	86	83	keratinocytes	keratinocyte	NOUN
dpc-1620	86	84	,	,	PUNCT
dpc-1620	86	85	usually	usually	ADV
dpc-1620	86	86	described	describe	VERB
dpc-1620	86	87	as	as	ADP
dpc-1620	86	88	rhomboidal	rhomboidal	NOUN
dpc-1620	86	89	in	in	ADP
dpc-1620	86	90	healthy	healthy	ADJ
dpc-1620	86	91	skin	skin	NOUN
dpc-1620	86	92	,	,	PUNCT
dpc-1620	86	93	tending	tend	VERB
dpc-1620	86	94	to	to	ADP
dpc-1620	86	95	linearity	linearity	NOUN
dpc-1620	86	96	in	in	ADP
dpc-1620	86	97	aged	aged	ADJ
dpc-1620	86	98	skin	skin	NOUN
dpc-1620	86	99	dermo	dermo	NOUN
dpc-1620	86	100	-	-	PUNCT
dpc-1620	86	101	epidermal	epidermal	ADJ
dpc-1620	86	102	junction	junction	NOUN
dpc-1620	86	103	polycyclic	polycyclic	NOUN
dpc-1620	86	104	papillary	papillary	NOUN
dpc-1620	86	105	contours	contours	VERB
dpc-1620	86	106	bulbous	bulbous	ADJ
dpc-1620	86	107	projections	projection	NOUN
dpc-1620	86	108	that	that	PRON
dpc-1620	86	109	can	can	AUX
dpc-1620	86	110	show	show	VERB
dpc-1620	86	111	a	a	DET
dpc-1620	86	112	variable	variable	ADJ
dpc-1620	86	113	convoluted	convoluted	ADJ
dpc-1620	86	114	arrangement	arrangement	NOUN
dpc-1620	86	115	sebaceous	sebaceous	ADJ
dpc-1620	86	116	glands	gland	NOUN
dpc-1620	86	117	annular	annular	ADJ
dpc-1620	86	118	structures	structure	NOUN
dpc-1620	86	119	with	with	ADP
dpc-1620	86	120	round	round	ADJ
dpc-1620	86	121	or	or	CCONJ
dpc-1620	86	122	oval	oval	NOUN
dpc-1620	86	123	shape	shape	NOUN
dpc-1620	86	124	,	,	PUNCT
dpc-1620	86	125	centered	center	VERB
dpc-1620	86	126	by	by	ADP
dpc-1620	86	127	hair	hair	NOUN
dpc-1620	86	128	follicles	follicle	VERB
dpc-1620	86	129	dermis	dermis	ADV
dpc-1620	86	130	thin	thin	ADJ
dpc-1620	86	131	reticular	reticular	ADJ
dpc-1620	86	132	collagen	collagen	NOUN
dpc-1620	86	133	bright	bright	ADJ
dpc-1620	86	134	,	,	PUNCT
dpc-1620	86	135	thin	thin	ADJ
dpc-1620	86	136	,	,	PUNCT
dpc-1620	86	137	fibrillar	fibrillar	ADJ
dpc-1620	86	138	structures	structure	NOUN
dpc-1620	86	139	creating	create	VERB
dpc-1620	86	140	a	a	DET
dpc-1620	86	141	weblike	weblike	NOUN
dpc-1620	86	142	appearance	appearance	NOUN
dpc-1620	86	143	coarse	coarse	NOUN
dpc-1620	86	144	collagen	collagen	NOUN
dpc-1620	86	145	coarse	coarse	NOUN
dpc-1620	86	146	filamentous	filamentous	ADJ
dpc-1620	86	147	,	,	PUNCT
dpc-1620	86	148	thick	thick	ADJ
dpc-1620	86	149	structures	structure	NOUN
dpc-1620	86	150	with	with	ADP
dpc-1620	86	151	a	a	DET
dpc-1620	86	152	tendency	tendency	NOUN
dpc-1620	86	153	to	to	PART
dpc-1620	86	154	be	be	AUX
dpc-1620	86	155	packed	pack	VERB
dpc-1620	86	156	huddle	huddle	NOUN
dpc-1620	86	157	collagen	collagen	NOUN
dpc-1620	86	158	large	large	ADJ
dpc-1620	86	159	blotches	blotch	NOUN
dpc-1620	86	160	of	of	ADP
dpc-1620	86	161	amorphous	amorphous	ADJ
dpc-1620	86	162	material	material	NOUN
dpc-1620	86	163	with	with	ADP
dpc-1620	86	164	hyporefractivity	hyporefractivity	NOUN
dpc-1620	86	165	curled	curl	VERB
dpc-1620	86	166	fibers	fiber	NOUN
dpc-1620	86	167	short	short	ADJ
dpc-1620	86	168	,	,	PUNCT
dpc-1620	86	169	thick	thick	ADJ
dpc-1620	86	170	,	,	PUNCT
dpc-1620	86	171	undulated	undulated	ADJ
dpc-1620	86	172	fibers	fiber	NOUN
dpc-1620	86	173	with	with	ADP
dpc-1620	86	174	high	high	ADJ
dpc-1620	86	175	refractivity	refractivity	NOUN
dpc-1620	86	176	figure	figure	NOUN
dpc-1620	86	177	1	1	NUM
dpc-1620	86	178	.	.	PUNCT
dpc-1620	87	1	reflectance	reflectance	NOUN
dpc-1620	87	2	confocal	confocal	ADJ
dpc-1620	87	3	micrographs	micrograph	NOUN
dpc-1620	87	4	showing	show	VERB
dpc-1620	87	5	morphologic	morphologic	ADJ
dpc-1620	87	6	aspects	aspect	NOUN
dpc-1620	87	7	of	of	ADP
dpc-1620	87	8	young	young	ADJ
dpc-1620	87	9	skin	skin	NOUN
dpc-1620	87	10	.	.	PUNCT
dpc-1620	88	1	(	(	PUNCT
dpc-1620	88	2	a	a	X
dpc-1620	88	3	)	)	PUNCT
dpc-1620	88	4	regular	regular	ADJ
dpc-1620	88	5	honeycomb	honeycomb	NOUN
dpc-1620	88	6	pattern	pattern	NOUN
dpc-1620	88	7	.	.	PUNCT
dpc-1620	89	1	(	(	PUNCT
dpc-1620	89	2	b	b	X
dpc-1620	89	3	)	)	PUNCT
dpc-1620	89	4	reticular	reticular	ADJ
dpc-1620	89	5	collagen	collagen	NOUN
dpc-1620	89	6	.	.	PUNCT
dpc-1620	90	1	scale	scale	NOUN
dpc-1620	90	2	bars	bar	NOUN
dpc-1620	90	3	=	=	SYM
dpc-1620	91	1	100	100	NUM
dpc-1620	91	2	µm	µm	NOUN
dpc-1620	91	3	.	.	PROPN
dpc-1620	91	4	4	4	NUM
dpc-1620	91	5	review	review	NOUN
dpc-1620	91	6	|	|	ADV
dpc-1620	91	7	dermatol	dermatol	ADJ
dpc-1620	91	8	pract	pract	NOUN
dpc-1620	91	9	concept	concept	NOUN
dpc-1620	91	10	.	.	PUNCT
dpc-1620	92	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	92	2	2021068	2021068	NUM
dpc-1620	92	3	skin	skin	NOUN
dpc-1620	92	4	aging	age	VERB
dpc-1620	92	5	signs	sign	NOUN
dpc-1620	92	6	and	and	CCONJ
dpc-1620	92	7	their	their	PRON
dpc-1620	92	8	correlation	correlation	NOUN
dpc-1620	92	9	with	with	ADP
dpc-1620	92	10	skin	skin	NOUN
dpc-1620	92	11	cancer	cancer	NOUN
dpc-1620	92	12	worldwide	worldwide	ADV
dpc-1620	92	13	,	,	PUNCT
dpc-1620	92	14	the	the	DET
dpc-1620	92	15	incidence	incidence	NOUN
dpc-1620	92	16	of	of	ADP
dpc-1620	92	17	skin	skin	NOUN
dpc-1620	92	18	cancer	cancer	NOUN
dpc-1620	92	19	is	be	AUX
dpc-1620	92	20	progressively	progressively	ADV
dpc-1620	92	21	increasing	increase	VERB
dpc-1620	92	22	,	,	PUNCT
dpc-1620	92	23	and	and	CCONJ
dpc-1620	92	24	two	two	NUM
dpc-1620	92	25	main	main	ADJ
dpc-1620	92	26	hypotheses	hypothesis	NOUN
dpc-1620	92	27	have	have	AUX
dpc-1620	92	28	been	be	AUX
dpc-1620	92	29	formulated	formulate	VERB
dpc-1620	92	30	to	to	PART
dpc-1620	92	31	explain	explain	VERB
dpc-1620	92	32	this	this	DET
dpc-1620	92	33	fact	fact	NOUN
dpc-1620	92	34	:	:	PUNCT
dpc-1620	92	35	increasing	increase	VERB
dpc-1620	92	36	sun	sun	NOUN
dpc-1620	92	37	exposure	exposure	NOUN
dpc-1620	92	38	and	and	CCONJ
dpc-1620	92	39	population	population	NOUN
dpc-1620	92	40	aging	aging	NOUN
dpc-1620	92	41	[	[	X
dpc-1620	92	42	25,26	25,26	NUM
dpc-1620	92	43	]	]	X
dpc-1620	92	44	.	.	PUNCT
dpc-1620	93	1	therefore	therefore	ADV
dpc-1620	93	2	,	,	PUNCT
dpc-1620	93	3	both	both	PRON
dpc-1620	93	4	chronological	chronological	ADJ
dpc-1620	93	5	aging	aging	NOUN
dpc-1620	93	6	and	and	CCONJ
dpc-1620	93	7	photoaging	photoaging	NOUN
dpc-1620	93	8	contribute	contribute	NOUN
dpc-1620	93	9	to	to	ADP
dpc-1620	93	10	skin	skin	NOUN
dpc-1620	93	11	cancer	cancer	NOUN
dpc-1620	93	12	development	development	NOUN
dpc-1620	93	13	.	.	PUNCT
dpc-1620	94	1	it	it	PRON
dpc-1620	94	2	has	have	AUX
dpc-1620	94	3	been	be	AUX
dpc-1620	94	4	shown	show	VERB
dpc-1620	94	5	that	that	SCONJ
dpc-1620	94	6	they	they	PRON
dpc-1620	94	7	also	also	ADV
dpc-1620	94	8	contribute	contribute	VERB
dpc-1620	94	9	to	to	ADP
dpc-1620	94	10	skin	skin	NOUN
dpc-1620	94	11	cancer	cancer	NOUN
dpc-1620	94	12	progression	progression	NOUN
dpc-1620	94	13	.	.	PUNCT
dpc-1620	95	1	epidermal	epidermal	ADJ
dpc-1620	95	2	changes	change	NOUN
dpc-1620	95	3	with	with	ADP
dpc-1620	95	4	aging	aging	NOUN
dpc-1620	95	5	,	,	PUNCT
dpc-1620	95	6	the	the	DET
dpc-1620	95	7	skin	skin	NOUN
dpc-1620	95	8	shows	show	VERB
dpc-1620	95	9	progressive	progressive	ADJ
dpc-1620	95	10	changes	change	NOUN
dpc-1620	95	11	that	that	PRON
dpc-1620	95	12	can	can	AUX
dpc-1620	95	13	involve	involve	VERB
dpc-1620	95	14	all	all	DET
dpc-1620	95	15	its	its	PRON
dpc-1620	95	16	layers	layer	NOUN
dpc-1620	95	17	.	.	PUNCT
dpc-1620	96	1	at	at	ADP
dpc-1620	96	2	the	the	DET
dpc-1620	96	3	epidermal	epidermal	ADJ
dpc-1620	96	4	level	level	NOUN
dpc-1620	96	5	,	,	PUNCT
dpc-1620	96	6	both	both	CCONJ
dpc-1620	96	7	quantitative	quantitative	ADJ
dpc-1620	96	8	and	and	CCONJ
dpc-1620	96	9	qualitative	qualitative	ADJ
dpc-1620	96	10	variations	variation	NOUN
dpc-1620	96	11	may	may	AUX
dpc-1620	96	12	occur	occur	VERB
dpc-1620	96	13	.	.	PUNCT
dpc-1620	97	1	accordingly	accordingly	ADV
dpc-1620	97	2	,	,	PUNCT
dpc-1620	97	3	the	the	DET
dpc-1620	97	4	skin	skin	NOUN
dpc-1620	97	5	shows	show	VERB
dpc-1620	97	6	a	a	DET
dpc-1620	97	7	progressive	progressive	ADJ
dpc-1620	97	8	reduction	reduction	NOUN
dpc-1620	97	9	in	in	ADP
dpc-1620	97	10	epidermal	epidermal	ADJ
dpc-1620	97	11	thickness	thickness	NOUN
dpc-1620	97	12	.	.	PUNCT
dpc-1620	98	1	however	however	ADV
dpc-1620	98	2	,	,	PUNCT
dpc-1620	98	3	some	some	DET
dpc-1620	98	4	middle	middle	ADJ
dpc-1620	98	5	-	-	PUNCT
dpc-1620	98	6	aged	aged	ADJ
dpc-1620	98	7	subjects	subject	NOUN
dpc-1620	98	8	may	may	AUX
dpc-1620	98	9	develop	develop	VERB
dpc-1620	98	10	hyperplasia	hyperplasia	NOUN
dpc-1620	98	11	with	with	ADP
dpc-1620	98	12	evidence	evidence	NOUN
dpc-1620	98	13	of	of	ADP
dpc-1620	98	14	polycyclic	polycyclic	NOUN
dpc-1620	98	15	papillary	papillary	NOUN
dpc-1620	98	16	contours	contours	NOUN
dpc-1620	98	17	(	(	PUNCT
dpc-1620	98	18	figure	figure	NOUN
dpc-1620	98	19	2a	2a	NUM
dpc-1620	98	20	)	)	PUNCT
dpc-1620	98	21	,	,	PUNCT
dpc-1620	98	22	histopathologically	histopathologically	ADV
dpc-1620	98	23	corresponding	correspond	VERB
dpc-1620	98	24	to	to	ADP
dpc-1620	98	25	solar	solar	ADJ
dpc-1620	98	26	lentigo	lentigo	ADV
dpc-1620	98	27	.	.	PUNCT
dpc-1620	99	1	therefore	therefore	ADV
dpc-1620	99	2	,	,	PUNCT
dpc-1620	99	3	it	it	PRON
dpc-1620	99	4	has	have	AUX
dpc-1620	99	5	been	be	AUX
dpc-1620	99	6	hypothesized	hypothesize	VERB
dpc-1620	99	7	that	that	SCONJ
dpc-1620	99	8	the	the	DET
dpc-1620	99	9	skin	skin	NOUN
dpc-1620	99	10	might	might	AUX
dpc-1620	99	11	develop	develop	VERB
dpc-1620	99	12	a	a	DET
dpc-1620	99	13	hyperplastic	hyperplastic	ADJ
dpc-1620	99	14	response	response	NOUN
dpc-1620	99	15	to	to	ADP
dpc-1620	99	16	solar	solar	ADJ
dpc-1620	99	17	damage	damage	NOUN
dpc-1620	99	18	and	and	CCONJ
dpc-1620	99	19	then	then	ADV
dpc-1620	99	20	show	show	VERB
dpc-1620	99	21	severe	severe	ADJ
dpc-1620	99	22	atrophy	atrophy	NOUN
dpc-1620	99	23	with	with	ADP
dpc-1620	99	24	progressive	progressive	ADJ
dpc-1620	99	25	thinning	thinning	NOUN
dpc-1620	99	26	[	[	X
dpc-1620	99	27	16	16	NUM
dpc-1620	99	28	]	]	PUNCT
dpc-1620	99	29	.	.	PUNCT
dpc-1620	100	1	additionally	additionally	ADV
dpc-1620	100	2	,	,	PUNCT
dpc-1620	100	3	there	there	PRON
dpc-1620	100	4	is	be	VERB
dpc-1620	100	5	a	a	DET
dpc-1620	100	6	change	change	NOUN
dpc-1620	100	7	of	of	ADP
dpc-1620	100	8	the	the	DET
dpc-1620	100	9	overall	overall	ADJ
dpc-1620	100	10	epidermal	epidermal	ADJ
dpc-1620	100	11	surface	surface	NOUN
dpc-1620	100	12	,	,	PUNCT
dpc-1620	100	13	showing	show	VERB
dpc-1620	100	14	a	a	DET
dpc-1620	100	15	prevalent	prevalent	ADJ
dpc-1620	100	16	linear	linear	ADJ
dpc-1620	100	17	furrow	furrow	NOUN
dpc-1620	100	18	pattern	pattern	NOUN
dpc-1620	100	19	with	with	ADP
dpc-1620	100	20	the	the	DET
dpc-1620	100	21	progressive	progressive	ADJ
dpc-1620	100	22	enlargement	enlargement	NOUN
dpc-1620	100	23	of	of	ADP
dpc-1620	100	24	a	a	DET
dpc-1620	100	25	rhomboidal	rhomboidal	NOUN
dpc-1620	100	26	pattern	pattern	NOUN
dpc-1620	100	27	and	and	CCONJ
dpc-1620	100	28	then	then	ADV
dpc-1620	100	29	a	a	DET
dpc-1620	100	30	linear	linear	ADJ
dpc-1620	100	31	trend	trend	NOUN
dpc-1620	100	32	without	without	ADP
dpc-1620	100	33	intersecting	intersect	VERB
dpc-1620	100	34	lines	line	NOUN
dpc-1620	100	35	[	[	X
dpc-1620	100	36	18,19	18,19	NUM
dpc-1620	100	37	]	]	PUNCT
dpc-1620	100	38	.	.	PUNCT
dpc-1620	101	1	the	the	DET
dpc-1620	101	2	regular	regular	ADJ
dpc-1620	101	3	honeycomb	honeycomb	NOUN
dpc-1620	101	4	pattern	pattern	NOUN
dpc-1620	101	5	,	,	PUNCT
dpc-1620	101	6	typical	typical	ADJ
dpc-1620	101	7	of	of	ADP
dpc-1620	101	8	young	young	ADJ
dpc-1620	101	9	age	age	NOUN
dpc-1620	101	10	,	,	PUNCT
dpc-1620	101	11	is	be	AUX
dpc-1620	101	12	substituted	substitute	VERB
dpc-1620	101	13	by	by	ADP
dpc-1620	101	14	an	an	DET
dpc-1620	101	15	irregular	irregular	ADJ
dpc-1620	101	16	honeycomb	honeycomb	NOUN
dpc-1620	101	17	pattern	pattern	NOUN
dpc-1620	101	18	during	during	ADP
dpc-1620	101	19	the	the	DET
dpc-1620	101	20	aging	age	VERB
dpc-1620	101	21	process	process	NOUN
dpc-1620	101	22	[	[	X
dpc-1620	101	23	13	13	NUM
dpc-1620	101	24	]	]	PUNCT
dpc-1620	101	25	.	.	PUNCT
dpc-1620	102	1	the	the	DET
dpc-1620	102	2	irregular	irregular	ADJ
dpc-1620	102	3	honeycomb	honeycomb	NOUN
dpc-1620	102	4	pattern	pattern	NOUN
dpc-1620	102	5	shows	show	VERB
dpc-1620	102	6	polygonal	polygonal	ADJ
dpc-1620	102	7	keratinocytes	keratinocyte	NOUN
dpc-1620	102	8	with	with	ADP
dpc-1620	102	9	ill	ill	ADV
dpc-1620	102	10	-	-	PUNCT
dpc-1620	102	11	defined	define	VERB
dpc-1620	102	12	cell	cell	NOUN
dpc-1620	102	13	borders	border	NOUN
dpc-1620	102	14	(	(	PUNCT
dpc-1620	102	15	figure	figure	NOUN
dpc-1620	102	16	2b	2b	NOUN
dpc-1620	102	17	)	)	PUNCT
dpc-1620	102	18	and	and	CCONJ
dpc-1620	102	19	variable	variable	ADJ
dpc-1620	102	20	size	size	NOUN
dpc-1620	102	21	and	and	CCONJ
dpc-1620	102	22	shape	shape	NOUN
dpc-1620	102	23	due	due	ADJ
dpc-1620	102	24	to	to	ADP
dpc-1620	102	25	varying	vary	VERB
dpc-1620	102	26	degrees	degree	NOUN
dpc-1620	102	27	of	of	ADP
dpc-1620	102	28	keratinocyte	keratinocyte	NOUN
dpc-1620	102	29	atypia	atypia	PROPN
dpc-1620	102	30	,	,	PUNCT
dpc-1620	102	31	with	with	ADP
dpc-1620	102	32	focal	focal	ADJ
dpc-1620	102	33	disarray	disarray	NOUN
dpc-1620	102	34	in	in	ADP
dpc-1620	102	35	lesions	lesion	NOUN
dpc-1620	102	36	such	such	ADJ
dpc-1620	102	37	as	as	ADP
dpc-1620	102	38	actinic	actinic	ADJ
dpc-1620	102	39	keratosis	keratosis	NOUN
dpc-1620	102	40	[	[	X
dpc-1620	102	41	9	9	NUM
dpc-1620	102	42	]	]	PUNCT
dpc-1620	102	43	.	.	PUNCT
dpc-1620	103	1	furthermore	furthermore	ADV
dpc-1620	103	2	,	,	PUNCT
dpc-1620	103	3	melanocytes	melanocyte	NOUN
dpc-1620	103	4	can	can	AUX
dpc-1620	103	5	be	be	AUX
dpc-1620	103	6	identified	identify	VERB
dpc-1620	103	7	in	in	ADP
dpc-1620	103	8	benign	benign	ADJ
dpc-1620	103	9	melanocytic	melanocytic	ADJ
dpc-1620	103	10	lesions	lesion	NOUN
dpc-1620	103	11	(	(	PUNCT
dpc-1620	103	12	eg	eg	NOUN
dpc-1620	103	13	,	,	PUNCT
dpc-1620	103	14	melasma	melasma	NOUN
dpc-1620	103	15	,	,	PUNCT
dpc-1620	103	16	nevus	nevus	ADJ
dpc-1620	103	17	)	)	PUNCT
dpc-1620	103	18	and	and	CCONJ
dpc-1620	103	19	malignant	malignant	ADJ
dpc-1620	103	20	melanocytic	melanocytic	ADJ
dpc-1620	103	21	lesions	lesion	NOUN
dpc-1620	103	22	(	(	PUNCT
dpc-1620	103	23	eg	eg	NOUN
dpc-1620	103	24	,	,	PUNCT
dpc-1620	103	25	melanoma	melanoma	NOUN
dpc-1620	103	26	)	)	PUNCT
dpc-1620	104	1	[	[	X
dpc-1620	104	2	16	16	NUM
dpc-1620	104	3	]	]	PUNCT
dpc-1620	104	4	.	.	PUNCT
dpc-1620	105	1	in	in	ADP
dpc-1620	105	2	addition	addition	NOUN
dpc-1620	105	3	,	,	PUNCT
dpc-1620	105	4	the	the	DET
dpc-1620	105	5	presence	presence	NOUN
dpc-1620	105	6	of	of	ADP
dpc-1620	105	7	dyspigmentation	dyspigmentation	NOUN
dpc-1620	105	8	at	at	ADP
dpc-1620	105	9	the	the	DET
dpc-1620	105	10	epidermal	epidermal	ADJ
dpc-1620	105	11	level	level	NOUN
dpc-1620	105	12	corresponds	correspond	VERB
dpc-1620	105	13	to	to	ADP
dpc-1620	105	14	the	the	DET
dpc-1620	105	15	visualization	visualization	NOUN
dpc-1620	105	16	with	with	ADP
dpc-1620	105	17	rcm	rcm	PROPN
dpc-1620	105	18	of	of	ADP
dpc-1620	105	19	bright	bright	ADJ
dpc-1620	105	20	keratinocytes	keratinocyte	NOUN
dpc-1620	105	21	assembled	assemble	VERB
dpc-1620	105	22	in	in	ADP
dpc-1620	105	23	the	the	DET
dpc-1620	105	24	context	context	NOUN
dpc-1620	105	25	of	of	ADP
dpc-1620	105	26	a	a	DET
dpc-1620	105	27	honeycomb	honeycomb	NOUN
dpc-1620	105	28	pattern	pattern	NOUN
dpc-1620	105	29	,	,	PUNCT
dpc-1620	105	30	called	call	VERB
dpc-1620	105	31	mottled	mottled	ADJ
dpc-1620	105	32	pigmentation	pigmentation	NOUN
dpc-1620	105	33	(	(	PUNCT
dpc-1620	105	34	figure	figure	NOUN
dpc-1620	105	35	2c	2c	NUM
dpc-1620	105	36	)	)	PUNCT
dpc-1620	106	1	[	[	X
dpc-1620	106	2	13	13	NUM
dpc-1620	106	3	]	]	PUNCT
dpc-1620	106	4	.	.	PUNCT
dpc-1620	106	5	mottled	mottled	ADJ
dpc-1620	106	6	pigmentation	pigmentation	NOUN
dpc-1620	106	7	,	,	PUNCT
dpc-1620	106	8	together	together	ADV
dpc-1620	106	9	with	with	ADP
dpc-1620	106	10	atypical	atypical	ADJ
dpc-1620	106	11	honeycomb	honeycomb	NOUN
dpc-1620	106	12	pattern	pattern	NOUN
dpc-1620	106	13	,	,	PUNCT
dpc-1620	106	14	has	have	AUX
dpc-1620	106	15	been	be	AUX
dpc-1620	106	16	shown	show	VERB
dpc-1620	106	17	to	to	PART
dpc-1620	106	18	be	be	AUX
dpc-1620	106	19	significantly	significantly	ADV
dpc-1620	106	20	more	more	ADV
dpc-1620	106	21	represented	represent	VERB
dpc-1620	106	22	in	in	ADP
dpc-1620	106	23	older	old	ADJ
dpc-1620	106	24	adults	adult	NOUN
dpc-1620	106	25	(	(	PUNCT
dpc-1620	106	26	aged	age	VERB
dpc-1620	106	27	older	old	ADJ
dpc-1620	106	28	than	than	ADP
dpc-1620	106	29	54	54	NUM
dpc-1620	106	30	years	year	NOUN
dpc-1620	106	31	)	)	PUNCT
dpc-1620	107	1	[	[	X
dpc-1620	107	2	27	27	NUM
dpc-1620	107	3	]	]	PUNCT
dpc-1620	107	4	.	.	PUNCT
dpc-1620	108	1	dej	dej	NOUN
dpc-1620	108	2	and	and	CCONJ
dpc-1620	108	3	dermal	dermal	VERB
dpc-1620	108	4	changes	change	NOUN
dpc-1620	108	5	the	the	DET
dpc-1620	108	6	exploration	exploration	NOUN
dpc-1620	108	7	with	with	ADP
dpc-1620	108	8	rcm	rcm	PROPN
dpc-1620	108	9	at	at	ADP
dpc-1620	108	10	the	the	DET
dpc-1620	108	11	dej	dej	NOUN
dpc-1620	108	12	and	and	CCONJ
dpc-1620	108	13	superficial	superficial	ADJ
dpc-1620	108	14	dermis	dermis	NOUN
dpc-1620	108	15	level	level	NOUN
dpc-1620	108	16	enables	enable	VERB
dpc-1620	108	17	the	the	DET
dpc-1620	108	18	visualization	visualization	NOUN
dpc-1620	108	19	of	of	ADP
dpc-1620	108	20	dermal	dermal	ADJ
dpc-1620	108	21	papillae	papillae	NOUN
dpc-1620	108	22	,	,	PUNCT
dpc-1620	108	23	blood	blood	NOUN
dpc-1620	108	24	figure	figure	NOUN
dpc-1620	108	25	2	2	NUM
dpc-1620	108	26	.	.	PUNCT
dpc-1620	108	27	reflectance	reflectance	NOUN
dpc-1620	108	28	confocal	confocal	ADJ
dpc-1620	108	29	microscopy	microscopy	NOUN
dpc-1620	108	30	appearance	appearance	NOUN
dpc-1620	108	31	of	of	ADP
dpc-1620	108	32	aged	aged	ADJ
dpc-1620	108	33	skin	skin	NOUN
dpc-1620	108	34	.	.	PUNCT
dpc-1620	109	1	(	(	PUNCT
dpc-1620	109	2	a	a	X
dpc-1620	109	3	)	)	PUNCT
dpc-1620	109	4	polycyclic	polycyclic	NOUN
dpc-1620	109	5	papillary	papillary	NOUN
dpc-1620	109	6	contours	contours	NOUN
dpc-1620	109	7	(	(	PUNCT
dpc-1620	109	8	green	green	ADJ
dpc-1620	109	9	circles	circle	NOUN
dpc-1620	109	10	)	)	PUNCT
dpc-1620	109	11	.	.	PUNCT
dpc-1620	110	1	(	(	PUNCT
dpc-1620	110	2	b	b	X
dpc-1620	110	3	)	)	PUNCT
dpc-1620	110	4	atypical	atypical	ADJ
dpc-1620	110	5	honeycomb	honeycomb	NOUN
dpc-1620	110	6	pattern	pattern	NOUN
dpc-1620	110	7	(	(	PUNCT
dpc-1620	110	8	pink	pink	ADJ
dpc-1620	110	9	stars	star	NOUN
dpc-1620	110	10	)	)	PUNCT
dpc-1620	110	11	.	.	PUNCT
dpc-1620	111	1	(	(	PUNCT
dpc-1620	111	2	c	c	X
dpc-1620	111	3	)	)	PUNCT
dpc-1620	111	4	mottled	mottled	ADJ
dpc-1620	111	5	pigmentation	pigmentation	NOUN
dpc-1620	111	6	(	(	PUNCT
dpc-1620	111	7	white	white	ADJ
dpc-1620	111	8	arrows	arrow	NOUN
dpc-1620	111	9	)	)	PUNCT
dpc-1620	111	10	.	.	PUNCT
dpc-1620	112	1	scale	scale	NOUN
dpc-1620	112	2	bars	bar	NOUN
dpc-1620	112	3	=	=	SYM
dpc-1620	112	4	100	100	NUM
dpc-1620	112	5	µm	µm	NOUN
dpc-1620	112	6	.	.	PUNCT
dpc-1620	112	7	figure	figure	NOUN
dpc-1620	112	8	3	3	NUM
dpc-1620	112	9	.	.	PUNCT
dpc-1620	112	10	reflectance	reflectance	NOUN
dpc-1620	112	11	confocal	confocal	ADJ
dpc-1620	112	12	micrographs	micrograph	NOUN
dpc-1620	112	13	at	at	ADP
dpc-1620	112	14	dermal	dermal	ADJ
dpc-1620	112	15	level	level	NOUN
dpc-1620	112	16	.	.	PUNCT
dpc-1620	113	1	(	(	PUNCT
dpc-1620	113	2	a	a	X
dpc-1620	113	3	)	)	PUNCT
dpc-1620	113	4	reticular	reticular	ADJ
dpc-1620	113	5	collagen	collagen	NOUN
dpc-1620	113	6	,	,	PUNCT
dpc-1620	113	7	typical	typical	ADJ
dpc-1620	113	8	of	of	ADP
dpc-1620	113	9	young	young	ADJ
dpc-1620	113	10	subjects	subject	NOUN
dpc-1620	113	11	.	.	PUNCT
dpc-1620	114	1	(	(	PUNCT
dpc-1620	114	2	b	b	X
dpc-1620	114	3	)	)	PUNCT
dpc-1620	114	4	coarse	coarse	ADJ
dpc-1620	114	5	collagen	collagen	NOUN
dpc-1620	114	6	.	.	PUNCT
dpc-1620	115	1	(	(	PUNCT
dpc-1620	115	2	b	b	X
dpc-1620	115	3	)	)	PUNCT
dpc-1620	115	4	huddle	huddle	NOUN
dpc-1620	115	5	collagen	collagen	NOUN
dpc-1620	115	6	.	.	PUNCT
dpc-1620	116	1	(	(	PUNCT
dpc-1620	116	2	c	c	X
dpc-1620	116	3	)	)	PUNCT
dpc-1620	116	4	curled	curled	ADJ
dpc-1620	116	5	fibers	fiber	NOUN
dpc-1620	116	6	in	in	ADP
dpc-1620	116	7	a	a	DET
dpc-1620	116	8	subject	subject	NOUN
dpc-1620	116	9	with	with	ADP
dpc-1620	116	10	solar	solar	ADJ
dpc-1620	116	11	elastosis	elastosis	NOUN
dpc-1620	116	12	(	(	PUNCT
dpc-1620	116	13	red	red	ADJ
dpc-1620	116	14	arrows	arrow	NOUN
dpc-1620	116	15	)	)	PUNCT
dpc-1620	116	16	.	.	PUNCT
dpc-1620	117	1	scale	scale	NOUN
dpc-1620	117	2	bars	bar	NOUN
dpc-1620	117	3	=	=	SYM
dpc-1620	117	4	100	100	NUM
dpc-1620	117	5	µm	µm	NOUN
dpc-1620	117	6	.	.	PUNCT
dpc-1620	117	7	review	review	NOUN
dpc-1620	117	8	|	|	ADV
dpc-1620	117	9	dermatol	dermatol	ADJ
dpc-1620	117	10	pract	pract	NOUN
dpc-1620	117	11	concept	concept	NOUN
dpc-1620	117	12	.	.	PUNCT
dpc-1620	118	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	118	2	2021068	2021068	NUM
dpc-1620	118	3	5	5	NUM
dpc-1620	118	4	vessels	vessel	NOUN
dpc-1620	118	5	within	within	ADP
dpc-1620	118	6	each	each	DET
dpc-1620	118	7	dermal	dermal	ADJ
dpc-1620	118	8	papilla	papilla	NOUN
dpc-1620	118	9	,	,	PUNCT
dpc-1620	118	10	and	and	CCONJ
dpc-1620	118	11	collagen	collagen	NOUN
dpc-1620	118	12	(	(	PUNCT
dpc-1620	118	13	table	table	NOUN
dpc-1620	118	14	1	1	NUM
dpc-1620	118	15	)	)	PUNCT
dpc-1620	118	16	.	.	PUNCT
dpc-1620	119	1	in	in	ADP
dpc-1620	119	2	a	a	DET
dpc-1620	119	3	study	study	NOUN
dpc-1620	119	4	of	of	ADP
dpc-1620	119	5	52	52	NUM
dpc-1620	119	6	japanese	japanese	ADJ
dpc-1620	119	7	subjects	subject	NOUN
dpc-1620	119	8	,	,	PUNCT
dpc-1620	119	9	reductions	reduction	NOUN
dpc-1620	119	10	in	in	ADP
dpc-1620	119	11	the	the	DET
dpc-1620	119	12	number	number	NOUN
dpc-1620	119	13	and	and	CCONJ
dpc-1620	119	14	size	size	NOUN
dpc-1620	119	15	of	of	ADP
dpc-1620	119	16	dermal	dermal	ADJ
dpc-1620	119	17	papillae	papillae	NOUN
dpc-1620	119	18	were	be	AUX
dpc-1620	119	19	observed	observe	VERB
dpc-1620	119	20	in	in	ADP
dpc-1620	119	21	subjects	subject	NOUN
dpc-1620	119	22	older	old	ADJ
dpc-1620	119	23	than	than	ADP
dpc-1620	119	24	50	50	NUM
dpc-1620	119	25	years	year	NOUN
dpc-1620	119	26	of	of	ADP
dpc-1620	119	27	age	age	NOUN
dpc-1620	119	28	compared	compare	VERB
dpc-1620	119	29	to	to	ADP
dpc-1620	119	30	a	a	DET
dpc-1620	119	31	group	group	NOUN
dpc-1620	119	32	of	of	ADP
dpc-1620	119	33	18to	18to	ADJ
dpc-1620	119	34	20	20	NUM
dpc-1620	119	35	-	-	PUNCT
dpc-1620	119	36	year	year	NOUN
dpc-1620	119	37	-	-	PUNCT
dpc-1620	119	38	old	old	ADJ
dpc-1620	119	39	healthy	healthy	ADJ
dpc-1620	119	40	individuals	individual	NOUN
dpc-1620	119	41	[	[	X
dpc-1620	119	42	28	28	NUM
dpc-1620	119	43	]	]	PUNCT
dpc-1620	119	44	.	.	PUNCT
dpc-1620	120	1	collagen	collagen	NOUN
dpc-1620	120	2	fibers	fiber	NOUN
dpc-1620	120	3	have	have	VERB
dpc-1620	120	4	specific	specific	ADJ
dpc-1620	120	5	features	feature	NOUN
dpc-1620	120	6	according	accord	VERB
dpc-1620	120	7	to	to	ADP
dpc-1620	120	8	age	age	NOUN
dpc-1620	120	9	and	and	CCONJ
dpc-1620	120	10	photodamage	photodamage	NOUN
dpc-1620	120	11	.	.	PUNCT
dpc-1620	121	1	in	in	ADP
dpc-1620	121	2	aged	aged	ADJ
dpc-1620	121	3	skin	skin	NOUN
dpc-1620	121	4	,	,	PUNCT
dpc-1620	121	5	morphologic	morphologic	ADJ
dpc-1620	121	6	variations	variation	NOUN
dpc-1620	121	7	of	of	ADP
dpc-1620	121	8	collagen	collagen	NOUN
dpc-1620	121	9	include	include	VERB
dpc-1620	121	10	coarse	coarse	ADJ
dpc-1620	121	11	collagen	collagen	NOUN
dpc-1620	121	12	,	,	PUNCT
dpc-1620	121	13	huddles	huddle	NOUN
dpc-1620	121	14	of	of	ADP
dpc-1620	121	15	collagen	collagen	NOUN
dpc-1620	121	16	,	,	PUNCT
dpc-1620	121	17	and	and	CCONJ
dpc-1620	121	18	curled	curl	VERB
dpc-1620	121	19	fibers	fiber	NOUN
dpc-1620	121	20	.	.	PUNCT
dpc-1620	122	1	coarse	coarse	ADJ
dpc-1620	122	2	collagen	collagen	NOUN
dpc-1620	122	3	is	be	AUX
dpc-1620	122	4	described	describe	VERB
dpc-1620	122	5	as	as	ADP
dpc-1620	122	6	a	a	DET
dpc-1620	122	7	coarse	coarse	ADJ
dpc-1620	122	8	 	 	SPACE
dpc-1620	122	9	network	network	NOUN
dpc-1620	122	10	of	of	ADP
dpc-1620	122	11	large	large	ADJ
dpc-1620	122	12	hyporeflecting	hyporeflecting	NOUN
dpc-1620	122	13	collagen	collagen	NOUN
dpc-1620	122	14	,	,	PUNCT
dpc-1620	122	15	huddle	huddle	NOUN
dpc-1620	122	16	collagen	collagen	NOUN
dpc-1620	122	17	appears	appear	VERB
dpc-1620	122	18	as	as	ADP
dpc-1620	122	19	large	large	ADJ
dpc-1620	122	20	blotches	blotch	NOUN
dpc-1620	122	21	of	of	ADP
dpc-1620	122	22	amorphous	amorphous	ADJ
dpc-1620	122	23	material	material	NOUN
dpc-1620	122	24	with	with	ADP
dpc-1620	122	25	hyporeflectivity	hyporeflectivity	NOUN
dpc-1620	122	26	,	,	PUNCT
dpc-1620	122	27	and	and	CCONJ
dpc-1620	122	28	curled	curl	VERB
dpc-1620	122	29	fibers	fiber	NOUN
dpc-1620	122	30	are	be	AUX
dpc-1620	122	31	visualized	visualize	VERB
dpc-1620	122	32	as	as	ADP
dpc-1620	122	33	undulated	undulated	ADJ
dpc-1620	122	34	bright	bright	ADJ
dpc-1620	122	35	structures	structure	NOUN
dpc-1620	122	36	corresponding	correspond	VERB
dpc-1620	122	37	to	to	ADP
dpc-1620	122	38	solar	solar	ADJ
dpc-1620	122	39	elastosis	elastosis	NOUN
dpc-1620	122	40	(	(	PUNCT
dpc-1620	122	41	figure	figure	NOUN
dpc-1620	122	42	3	3	NUM
dpc-1620	122	43	)	)	PUNCT
dpc-1620	123	1	[	[	X
dpc-1620	123	2	13	13	NUM
dpc-1620	123	3	]	]	PUNCT
dpc-1620	123	4	.	.	PUNCT
dpc-1620	124	1	different	different	ADJ
dpc-1620	124	2	collagen	collagen	NOUN
dpc-1620	124	3	types	type	NOUN
dpc-1620	124	4	have	have	AUX
dpc-1620	124	5	been	be	AUX
dpc-1620	124	6	observed	observe	VERB
dpc-1620	124	7	throughout	throughout	ADP
dpc-1620	124	8	aging	age	VERB
dpc-1620	124	9	in	in	ADP
dpc-1620	124	10	a	a	DET
dpc-1620	124	11	group	group	NOUN
dpc-1620	124	12	of	of	ADP
dpc-1620	124	13	63	63	NUM
dpc-1620	124	14	italian	italian	ADJ
dpc-1620	124	15	women	woman	NOUN
dpc-1620	124	16	,	,	PUNCT
dpc-1620	124	17	with	with	ADP
dpc-1620	124	18	reticular	reticular	ADJ
dpc-1620	124	19	collagen	collagen	NOUN
dpc-1620	124	20	being	be	AUX
dpc-1620	124	21	less	less	ADV
dpc-1620	124	22	evident	evident	ADJ
dpc-1620	124	23	in	in	ADP
dpc-1620	124	24	subjects	subject	NOUN
dpc-1620	124	25	older	old	ADJ
dpc-1620	124	26	than	than	ADP
dpc-1620	124	27	35	35	NUM
dpc-1620	124	28	years	year	NOUN
dpc-1620	124	29	and	and	CCONJ
dpc-1620	124	30	coarse	coarse	ADV
dpc-1620	124	31	and	and	CCONJ
dpc-1620	124	32	huddled	huddle	VERB
dpc-1620	124	33	collagen	collagen	NOUN
dpc-1620	124	34	and	and	CCONJ
dpc-1620	124	35	curled	curled	ADJ
dpc-1620	124	36	fibers	fiber	NOUN
dpc-1620	124	37	becoming	becoming	AUX
dpc-1620	124	38	increasingly	increasingly	ADV
dpc-1620	124	39	represented	represent	VERB
dpc-1620	124	40	[	[	PUNCT
dpc-1620	124	41	13	13	NUM
dpc-1620	124	42	]	]	PUNCT
dpc-1620	124	43	.	.	PUNCT
dpc-1620	125	1	similar	similar	ADJ
dpc-1620	125	2	results	result	NOUN
dpc-1620	125	3	were	be	AUX
dpc-1620	125	4	observed	observe	VERB
dpc-1620	125	5	in	in	ADP
dpc-1620	125	6	a	a	DET
dpc-1620	125	7	group	group	NOUN
dpc-1620	125	8	of	of	ADP
dpc-1620	125	9	44	44	NUM
dpc-1620	125	10	brazilian	brazilian	ADJ
dpc-1620	125	11	women	woman	NOUN
dpc-1620	125	12	[	[	X
dpc-1620	125	13	29	29	NUM
dpc-1620	125	14	]	]	PUNCT
dpc-1620	125	15	.	.	PUNCT
dpc-1620	126	1	skin	skin	NOUN
dpc-1620	126	2	aging	age	VERB
dpc-1620	126	3	quantification	quantification	NOUN
dpc-1620	126	4	in	in	ADP
dpc-1620	126	5	photo	photo	NOUN
dpc-1620	126	6	-	-	PUNCT
dpc-1620	126	7	exposed	expose	VERB
dpc-1620	126	8	and	and	CCONJ
dpc-1620	126	9	nonphoto	nonphoto	NOUN
dpc-1620	126	10	-	-	PUNCT
dpc-1620	126	11	exposed	expose	VERB
dpc-1620	126	12	skin	skin	NOUN
dpc-1620	126	13	different	different	ADJ
dpc-1620	126	14	scores	score	NOUN
dpc-1620	126	15	have	have	AUX
dpc-1620	126	16	been	be	AUX
dpc-1620	126	17	developed	develop	VERB
dpc-1620	126	18	to	to	PART
dpc-1620	126	19	quantify	quantify	VERB
dpc-1620	126	20	skin	skin	NOUN
dpc-1620	126	21	aging	aging	NOUN
dpc-1620	126	22	.	.	PUNCT
dpc-1620	127	1	an	an	DET
dpc-1620	127	2	epidermal	epidermal	ADJ
dpc-1620	127	3	disarray	disarray	NOUN
dpc-1620	127	4	score	score	NOUN
dpc-1620	127	5	,	,	PUNCT
dpc-1620	127	6	which	which	PRON
dpc-1620	127	7	ranges	range	VERB
dpc-1620	127	8	from	from	ADP
dpc-1620	127	9	0	0	NUM
dpc-1620	127	10	to	to	ADP
dpc-1620	127	11	9	9	NUM
dpc-1620	127	12	,	,	PUNCT
dpc-1620	127	13	is	be	AUX
dpc-1620	127	14	calculated	calculate	VERB
dpc-1620	127	15	from	from	ADP
dpc-1620	127	16	an	an	DET
dpc-1620	127	17	irregular	irregular	ADJ
dpc-1620	127	18	honeycomb	honeycomb	NOUN
dpc-1620	127	19	pattern	pattern	NOUN
dpc-1620	127	20	,	,	PUNCT
dpc-1620	127	21	the	the	DET
dpc-1620	127	22	epidermal	epidermal	ADJ
dpc-1620	127	23	thickness	thickness	NOUN
dpc-1620	127	24	,	,	PUNCT
dpc-1620	127	25	and	and	CCONJ
dpc-1620	127	26	a	a	DET
dpc-1620	127	27	furrow	furrow	NOUN
dpc-1620	127	28	pattern	pattern	NOUN
dpc-1620	127	29	.	.	PUNCT
dpc-1620	128	1	an	an	DET
dpc-1620	128	2	epidermal	epidermal	ADJ
dpc-1620	128	3	hyperplasia	hyperplasia	NOUN
dpc-1620	128	4	score	score	NOUN
dpc-1620	128	5	,	,	PUNCT
dpc-1620	128	6	which	which	PRON
dpc-1620	128	7	also	also	ADV
dpc-1620	128	8	ranges	range	VERB
dpc-1620	128	9	from	from	ADP
dpc-1620	128	10	0	0	NUM
dpc-1620	128	11	to	to	ADP
dpc-1620	128	12	9	9	NUM
dpc-1620	128	13	,	,	PUNCT
dpc-1620	128	14	includes	include	VERB
dpc-1620	128	15	the	the	DET
dpc-1620	128	16	evaluation	evaluation	NOUN
dpc-1620	128	17	of	of	ADP
dpc-1620	128	18	mottled	mottled	ADJ
dpc-1620	128	19	pigmentation	pigmentation	NOUN
dpc-1620	128	20	,	,	PUNCT
dpc-1620	128	21	polycyclic	polycyclic	NOUN
dpc-1620	128	22	papillary	papillary	NOUN
dpc-1620	128	23	contours	contours	NOUN
dpc-1620	128	24	,	,	PUNCT
dpc-1620	128	25	and	and	CCONJ
dpc-1620	128	26	epidermal	epidermal	ADJ
dpc-1620	128	27	thickness	thickness	NOUN
dpc-1620	128	28	.	.	PUNCT
dpc-1620	129	1	a	a	DET
dpc-1620	129	2	collagen	collagen	NOUN
dpc-1620	129	3	alteration	alteration	NOUN
dpc-1620	129	4	score	score	NOUN
dpc-1620	129	5	,	,	PUNCT
dpc-1620	129	6	which	which	PRON
dpc-1620	129	7	ranges	range	VERB
dpc-1620	129	8	from	from	ADP
dpc-1620	129	9	0	0	NUM
dpc-1620	129	10	to	to	ADP
dpc-1620	129	11	12	12	NUM
dpc-1620	129	12	,	,	PUNCT
dpc-1620	129	13	is	be	AUX
dpc-1620	129	14	estimated	estimate	VERB
dpc-1620	129	15	from	from	ADP
dpc-1620	129	16	the	the	DET
dpc-1620	129	17	extent	extent	NOUN
dpc-1620	129	18	of	of	ADP
dpc-1620	129	19	each	each	DET
dpc-1620	129	20	collagen	collagen	NOUN
dpc-1620	129	21	type	type	NOUN
dpc-1620	129	22	(	(	PUNCT
dpc-1620	129	23	scored	score	VERB
dpc-1620	129	24	from	from	ADP
dpc-1620	129	25	0	0	NUM
dpc-1620	129	26	to	to	PART
dpc-1620	129	27	4	4	NUM
dpc-1620	129	28	)	)	PUNCT
dpc-1620	129	29	multiplied	multiply	VERB
dpc-1620	129	30	by	by	ADP
dpc-1620	129	31	its	its	PRON
dpc-1620	129	32	coefficient	coefficient	NOUN
dpc-1620	129	33	;	;	PUNCT
dpc-1620	129	34	the	the	DET
dpc-1620	129	35	coefficient	coefficient	NOUN
dpc-1620	129	36	is	be	AUX
dpc-1620	129	37	3	3	NUM
dpc-1620	129	38	for	for	ADP
dpc-1620	129	39	curled	curled	ADJ
dpc-1620	129	40	fibers	fiber	NOUN
dpc-1620	129	41	,	,	PUNCT
dpc-1620	129	42	2	2	NUM
dpc-1620	129	43	for	for	ADP
dpc-1620	129	44	huddles	huddle	NOUN
dpc-1620	129	45	of	of	ADP
dpc-1620	129	46	collagen	collagen	NOUN
dpc-1620	129	47	,	,	PUNCT
dpc-1620	129	48	1	1	NUM
dpc-1620	129	49	for	for	ADP
dpc-1620	129	50	coarse	coarse	ADJ
dpc-1620	129	51	collagen	collagen	NOUN
dpc-1620	129	52	structures	structure	NOUN
dpc-1620	129	53	,	,	PUNCT
dpc-1620	129	54	and	and	CCONJ
dpc-1620	129	55	0	0	NUM
dpc-1620	129	56	for	for	ADP
dpc-1620	129	57	thin	thin	ADJ
dpc-1620	129	58	reticulated	reticulated	ADJ
dpc-1620	129	59	collagen	collagen	NOUN
dpc-1620	129	60	[	[	X
dpc-1620	129	61	17	17	NUM
dpc-1620	129	62	]	]	PUNCT
dpc-1620	129	63	.	.	PUNCT
dpc-1620	130	1	a	a	DET
dpc-1620	130	2	study	study	NOUN
dpc-1620	130	3	evaluated	evaluate	VERB
dpc-1620	130	4	the	the	DET
dpc-1620	130	5	distribution	distribution	NOUN
dpc-1620	130	6	of	of	ADP
dpc-1620	130	7	these	these	DET
dpc-1620	130	8	scores	score	NOUN
dpc-1620	130	9	,	,	PUNCT
dpc-1620	130	10	employing	employ	VERB
dpc-1620	130	11	rcm	rcm	NOUN
dpc-1620	130	12	images	image	NOUN
dpc-1620	130	13	of	of	ADP
dpc-1620	130	14	the	the	DET
dpc-1620	130	15	face	face	NOUN
dpc-1620	130	16	in	in	ADP
dpc-1620	130	17	correspondence	correspondence	NOUN
dpc-1620	130	18	of	of	ADP
dpc-1620	130	19	the	the	DET
dpc-1620	130	20	left	left	ADJ
dpc-1620	130	21	malar	malar	ADJ
dpc-1620	130	22	eminence	eminence	NOUN
dpc-1620	130	23	,	,	PUNCT
dpc-1620	130	24	in	in	ADP
dpc-1620	130	25	a	a	DET
dpc-1620	130	26	population	population	NOUN
dpc-1620	130	27	of	of	ADP
dpc-1620	130	28	50	50	NUM
dpc-1620	130	29	women	woman	NOUN
dpc-1620	130	30	between	between	ADP
dpc-1620	130	31	24	24	NUM
dpc-1620	130	32	and	and	CCONJ
dpc-1620	130	33	88	88	NUM
dpc-1620	130	34	years	year	NOUN
dpc-1620	130	35	old	old	ADJ
dpc-1620	130	36	[	[	X
dpc-1620	130	37	17	17	NUM
dpc-1620	130	38	]	]	PUNCT
dpc-1620	130	39	.	.	PUNCT
dpc-1620	131	1	according	accord	VERB
dpc-1620	131	2	to	to	ADP
dpc-1620	131	3	the	the	DET
dpc-1620	131	4	study	study	NOUN
dpc-1620	131	5	,	,	PUNCT
dpc-1620	131	6	the	the	DET
dpc-1620	131	7	epidermal	epidermal	ADJ
dpc-1620	131	8	disarray	disarray	NOUN
dpc-1620	131	9	score	score	NOUN
dpc-1620	131	10	was	be	AUX
dpc-1620	131	11	stable	stable	ADJ
dpc-1620	131	12	until	until	ADP
dpc-1620	131	13	age	age	NOUN
dpc-1620	131	14	65	65	NUM
dpc-1620	131	15	years	year	NOUN
dpc-1620	131	16	and	and	CCONJ
dpc-1620	131	17	then	then	ADV
dpc-1620	131	18	increased	increase	VERB
dpc-1620	131	19	,	,	PUNCT
dpc-1620	131	20	while	while	SCONJ
dpc-1620	131	21	the	the	DET
dpc-1620	131	22	epidermal	epidermal	ADJ
dpc-1620	131	23	hyperplasia	hyperplasia	NOUN
dpc-1620	131	24	and	and	CCONJ
dpc-1620	131	25	collagen	collagen	NOUN
dpc-1620	131	26	scores	score	NOUN
dpc-1620	131	27	showed	show	VERB
dpc-1620	131	28	proportional	proportional	ADJ
dpc-1620	131	29	increases	increase	NOUN
dpc-1620	131	30	with	with	ADP
dpc-1620	131	31	age	age	NOUN
dpc-1620	131	32	.	.	PUNCT
dpc-1620	132	1	skin	skin	NOUN
dpc-1620	132	2	aging	age	VERB
dpc-1620	132	3	scores	score	NOUN
dpc-1620	132	4	have	have	AUX
dpc-1620	132	5	also	also	ADV
dpc-1620	132	6	been	be	AUX
dpc-1620	132	7	explored	explore	VERB
dpc-1620	132	8	in	in	ADP
dpc-1620	132	9	a	a	DET
dpc-1620	132	10	larger	large	ADJ
dpc-1620	132	11	cohort	cohort	NOUN
dpc-1620	132	12	of	of	ADP
dpc-1620	132	13	209	209	NUM
dpc-1620	132	14	french	french	ADJ
dpc-1620	132	15	subjects	subject	NOUN
dpc-1620	132	16	between	between	ADP
dpc-1620	132	17	74	74	NUM
dpc-1620	132	18	and	and	CCONJ
dpc-1620	132	19	81	81	NUM
dpc-1620	132	20	years	year	NOUN
dpc-1620	132	21	of	of	ADP
dpc-1620	132	22	age	age	NOUN
dpc-1620	132	23	[	[	X
dpc-1620	132	24	19	19	NUM
dpc-1620	132	25	]	]	PUNCT
dpc-1620	132	26	.	.	PUNCT
dpc-1620	133	1	the	the	DET
dpc-1620	133	2	study	study	NOUN
dpc-1620	133	3	analyzed	analyze	VERB
dpc-1620	133	4	differences	difference	NOUN
dpc-1620	133	5	between	between	ADP
dpc-1620	133	6	non	non	ADJ
dpc-1620	133	7	-	-	ADJ
dpc-1620	133	8	photo	photo	NOUN
dpc-1620	133	9	-	-	PUNCT
dpc-1620	133	10	exposed	expose	VERB
dpc-1620	133	11	(	(	PUNCT
dpc-1620	133	12	volar	volar	ADJ
dpc-1620	133	13	arm	arm	NOUN
dpc-1620	133	14	)	)	PUNCT
dpc-1620	133	15	,	,	PUNCT
dpc-1620	133	16	chronically	chronically	ADV
dpc-1620	133	17	photo	photo	NOUN
dpc-1620	133	18	-	-	PUNCT
dpc-1620	133	19	exposed	expose	VERB
dpc-1620	133	20	(	(	PUNCT
dpc-1620	133	21	face	face	NOUN
dpc-1620	133	22	)	)	PUNCT
dpc-1620	133	23	and	and	CCONJ
dpc-1620	133	24	intermittently	intermittently	ADV
dpc-1620	133	25	photo	photo	NOUN
dpc-1620	133	26	-	-	PUNCT
dpc-1620	133	27	exposed	expose	VERB
dpc-1620	133	28	(	(	PUNCT
dpc-1620	133	29	dorsal	dorsal	NOUN
dpc-1620	133	30	forearm	forearm	NOUN
dpc-1620	133	31	)	)	PUNCT
dpc-1620	133	32	areas	area	NOUN
dpc-1620	133	33	.	.	PUNCT
dpc-1620	134	1	photo	photo	NOUN
dpc-1620	134	2	-	-	PUNCT
dpc-1620	134	3	exposed	expose	VERB
dpc-1620	134	4	areas	area	NOUN
dpc-1620	134	5	had	have	VERB
dpc-1620	134	6	significant	significant	ADJ
dpc-1620	134	7	higher	high	ADJ
dpc-1620	134	8	epidermal	epidermal	ADJ
dpc-1620	134	9	disarray	disarray	NOUN
dpc-1620	134	10	figure	figure	NOUN
dpc-1620	134	11	4	4	NUM
dpc-1620	134	12	.	.	PUNCT
dpc-1620	134	13	clinical	clinical	ADJ
dpc-1620	134	14	photograph	photograph	NOUN
dpc-1620	134	15	(	(	PUNCT
dpc-1620	134	16	a	a	NOUN
dpc-1620	134	17	)	)	PUNCT
dpc-1620	134	18	and	and	CCONJ
dpc-1620	134	19	dermoscopic	dermoscopic	NOUN
dpc-1620	134	20	image	image	NOUN
dpc-1620	134	21	(	(	PUNCT
dpc-1620	134	22	b	b	NOUN
dpc-1620	134	23	)	)	PUNCT
dpc-1620	134	24	of	of	ADP
dpc-1620	134	25	a	a	DET
dpc-1620	134	26	pigmented	pigmented	ADJ
dpc-1620	134	27	actinic	actinic	ADJ
dpc-1620	134	28	keratosis	keratosis	NOUN
dpc-1620	134	29	of	of	ADP
dpc-1620	134	30	the	the	DET
dpc-1620	134	31	left	left	ADJ
dpc-1620	134	32	cheek	cheek	NOUN
dpc-1620	134	33	in	in	ADP
dpc-1620	134	34	a	a	DET
dpc-1620	134	35	70	70	NUM
dpc-1620	134	36	-	-	PUNCT
dpc-1620	134	37	year	year	NOUN
dpc-1620	134	38	-	-	PUNCT
dpc-1620	134	39	old	old	ADJ
dpc-1620	134	40	woman	woman	NOUN
dpc-1620	134	41	.	.	PUNCT
dpc-1620	135	1	(	(	PUNCT
dpc-1620	135	2	c	c	X
dpc-1620	135	3	)	)	PUNCT
dpc-1620	135	4	reflectance	reflectance	NOUN
dpc-1620	135	5	confocal	confocal	ADJ
dpc-1620	135	6	micrograph	micrograph	NOUN
dpc-1620	135	7	of	of	ADP
dpc-1620	135	8	the	the	DET
dpc-1620	135	9	area	area	NOUN
dpc-1620	135	10	marked	mark	VERB
dpc-1620	135	11	by	by	ADP
dpc-1620	135	12	a	a	DET
dpc-1620	135	13	pink	pink	ADJ
dpc-1620	135	14	square	square	NOUN
dpc-1620	135	15	in	in	ADP
dpc-1620	135	16	b	b	PROPN
dpc-1620	135	17	,	,	PUNCT
dpc-1620	135	18	showing	show	VERB
dpc-1620	135	19	an	an	DET
dpc-1620	135	20	atypical	atypical	ADJ
dpc-1620	135	21	honeycomb	honeycomb	NOUN
dpc-1620	135	22	pattern	pattern	NOUN
dpc-1620	135	23	(	(	PUNCT
dpc-1620	135	24	white	white	ADJ
dpc-1620	135	25	squares	square	NOUN
dpc-1620	135	26	)	)	PUNCT
dpc-1620	135	27	.	.	PUNCT
dpc-1620	136	1	(	(	PUNCT
dpc-1620	136	2	d	d	X
dpc-1620	136	3	)	)	PUNCT
dpc-1620	136	4	clinical	clinical	ADJ
dpc-1620	136	5	photograph	photograph	NOUN
dpc-1620	136	6	and	and	CCONJ
dpc-1620	136	7	(	(	PUNCT
dpc-1620	136	8	e	e	NOUN
dpc-1620	136	9	)	)	PUNCT
dpc-1620	136	10	dermoscopic	dermoscopic	ADJ
dpc-1620	136	11	image	image	NOUN
dpc-1620	136	12	of	of	ADP
dpc-1620	136	13	a	a	DET
dpc-1620	136	14	lentigo	lentigo	ADJ
dpc-1620	136	15	maligna	maligna	NOUN
dpc-1620	136	16	on	on	ADP
dpc-1620	136	17	the	the	DET
dpc-1620	136	18	left	left	ADJ
dpc-1620	136	19	cheek	cheek	NOUN
dpc-1620	136	20	of	of	ADP
dpc-1620	136	21	a	a	DET
dpc-1620	136	22	64	64	NUM
dpc-1620	136	23	-	-	PUNCT
dpc-1620	136	24	year	year	NOUN
dpc-1620	136	25	-	-	PUNCT
dpc-1620	136	26	old	old	ADJ
dpc-1620	136	27	woman	woman	NOUN
dpc-1620	136	28	.	.	PUNCT
dpc-1620	137	1	(	(	PUNCT
dpc-1620	137	2	f	f	X
dpc-1620	137	3	)	)	PUNCT
dpc-1620	137	4	reflectance	reflectance	NOUN
dpc-1620	137	5	confocal	confocal	ADJ
dpc-1620	137	6	micrograph	micrograph	NOUN
dpc-1620	137	7	of	of	ADP
dpc-1620	137	8	the	the	DET
dpc-1620	137	9	area	area	NOUN
dpc-1620	137	10	marked	mark	VERB
dpc-1620	137	11	by	by	ADP
dpc-1620	137	12	a	a	DET
dpc-1620	137	13	green	green	ADJ
dpc-1620	137	14	square	square	NOUN
dpc-1620	137	15	in	in	ADP
dpc-1620	137	16	e	e	NOUN
dpc-1620	137	17	,	,	PUNCT
dpc-1620	137	18	showing	show	VERB
dpc-1620	137	19	atypical	atypical	ADJ
dpc-1620	137	20	cells	cell	NOUN
dpc-1620	137	21	(	(	PUNCT
dpc-1620	137	22	both	both	CCONJ
dpc-1620	137	23	rounded	rounded	ADJ
dpc-1620	137	24	and	and	CCONJ
dpc-1620	137	25	dendritic	dendritic	ADJ
dpc-1620	137	26	)	)	PUNCT
dpc-1620	137	27	infiltrating	infiltrate	VERB
dpc-1620	137	28	the	the	DET
dpc-1620	137	29	hair	hair	NOUN
dpc-1620	137	30	follicle	follicle	NOUN
dpc-1620	137	31	(	(	PUNCT
dpc-1620	137	32	green	green	ADJ
dpc-1620	137	33	arrows	arrow	NOUN
dpc-1620	137	34	)	)	PUNCT
dpc-1620	137	35	.	.	PUNCT
dpc-1620	138	1	scale	scale	NOUN
dpc-1620	138	2	bars	bar	NOUN
dpc-1620	138	3	=	=	SYM
dpc-1620	138	4	100	100	NUM
dpc-1620	138	5	µm	µm	NOUN
dpc-1620	138	6	.	.	PROPN
dpc-1620	138	7	6	6	NUM
dpc-1620	138	8	review	review	NOUN
dpc-1620	138	9	|	|	ADV
dpc-1620	138	10	dermatol	dermatol	ADJ
dpc-1620	138	11	pract	pract	NOUN
dpc-1620	138	12	concept	concept	NOUN
dpc-1620	138	13	.	.	PUNCT
dpc-1620	139	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	139	2	2021068	2021068	NUM
dpc-1620	139	3	and	and	CCONJ
dpc-1620	139	4	epidermal	epidermal	ADJ
dpc-1620	139	5	hyperplasia	hyperplasia	NOUN
dpc-1620	139	6	scores	score	NOUN
dpc-1620	139	7	than	than	ADP
dpc-1620	139	8	non	non	ADJ
dpc-1620	139	9	-	-	ADJ
dpc-1620	139	10	photo	photo	ADJ
dpc-1620	139	11	-	-	PUNCT
dpc-1620	139	12	exposed	expose	VERB
dpc-1620	139	13	areas	area	NOUN
dpc-1620	139	14	,	,	PUNCT
dpc-1620	139	15	while	while	SCONJ
dpc-1620	139	16	the	the	DET
dpc-1620	139	17	collagen	collagen	NOUN
dpc-1620	139	18	score	score	NOUN
dpc-1620	139	19	was	be	AUX
dpc-1620	139	20	higher	high	ADJ
dpc-1620	139	21	in	in	ADP
dpc-1620	139	22	the	the	DET
dpc-1620	139	23	intermittently	intermittently	ADV
dpc-1620	139	24	photo	photo	NOUN
dpc-1620	139	25	-	-	PUNCT
dpc-1620	139	26	exposed	expose	VERB
dpc-1620	139	27	skin	skin	NOUN
dpc-1620	139	28	than	than	ADP
dpc-1620	139	29	the	the	DET
dpc-1620	139	30	non	non	ADJ
dpc-1620	139	31	-	-	ADJ
dpc-1620	139	32	photo	photo	ADJ
dpc-1620	139	33	-	-	PUNCT
dpc-1620	139	34	exposed	expose	VERB
dpc-1620	139	35	skin	skin	NOUN
dpc-1620	139	36	[	[	X
dpc-1620	139	37	19	19	NUM
dpc-1620	139	38	]	]	PUNCT
dpc-1620	139	39	.	.	PUNCT
dpc-1620	140	1	other	other	ADJ
dpc-1620	140	2	studies	study	NOUN
dpc-1620	140	3	have	have	AUX
dpc-1620	140	4	compared	compare	VERB
dpc-1620	140	5	rcm	rcm	PROPN
dpc-1620	140	6	features	feature	NOUN
dpc-1620	140	7	between	between	ADP
dpc-1620	140	8	non	non	ADJ
dpc-1620	140	9	-	-	ADJ
dpc-1620	140	10	photo	photo	ADJ
dpc-1620	140	11	-	-	PUNCT
dpc-1620	140	12	exposed	expose	VERB
dpc-1620	140	13	and	and	CCONJ
dpc-1620	140	14	photo	photo	NOUN
dpc-1620	140	15	-	-	PUNCT
dpc-1620	140	16	exposed	expose	VERB
dpc-1620	140	17	skin	skin	NOUN
dpc-1620	140	18	.	.	PUNCT
dpc-1620	141	1	these	these	DET
dpc-1620	141	2	studies	study	NOUN
dpc-1620	141	3	identified	identify	VERB
dpc-1620	141	4	epidermal	epidermal	ADJ
dpc-1620	141	5	,	,	PUNCT
dpc-1620	141	6	dej	dej	NOUN
dpc-1620	141	7	and	and	CCONJ
dpc-1620	141	8	dermal	dermal	ADJ
dpc-1620	141	9	changes	change	NOUN
dpc-1620	141	10	that	that	PRON
dpc-1620	141	11	were	be	AUX
dpc-1620	141	12	related	relate	VERB
dpc-1620	141	13	to	to	ADP
dpc-1620	141	14	chronological	chronological	ADJ
dpc-1620	141	15	aging	aging	NOUN
dpc-1620	141	16	and	and	CCONJ
dpc-1620	141	17	that	that	PRON
dpc-1620	141	18	were	be	AUX
dpc-1620	141	19	more	more	ADV
dpc-1620	141	20	evident	evident	ADJ
dpc-1620	141	21	in	in	ADP
dpc-1620	141	22	photo	photo	NOUN
dpc-1620	141	23	-	-	PUNCT
dpc-1620	141	24	exposed	expose	VERB
dpc-1620	141	25	areas	area	NOUN
dpc-1620	141	26	.	.	PUNCT
dpc-1620	142	1	these	these	DET
dpc-1620	142	2	changes	change	NOUN
dpc-1620	142	3	included	include	VERB
dpc-1620	142	4	the	the	DET
dpc-1620	142	5	appearance	appearance	NOUN
dpc-1620	142	6	of	of	ADP
dpc-1620	142	7	linear	linear	PROPN
dpc-1620	142	8	furrows	furrow	NOUN
dpc-1620	142	9	,	,	PUNCT
dpc-1620	142	10	mottled	mottled	ADJ
dpc-1620	142	11	pigmentation	pigmentation	NOUN
dpc-1620	142	12	,	,	PUNCT
dpc-1620	142	13	atypical	atypical	ADJ
dpc-1620	142	14	honeycomb	honeycomb	NOUN
dpc-1620	142	15	pattern	pattern	NOUN
dpc-1620	142	16	,	,	PUNCT
dpc-1620	142	17	irregular	irregular	ADJ
dpc-1620	142	18	ringed	ringed	ADJ
dpc-1620	142	19	pattern	pattern	NOUN
dpc-1620	142	20	,	,	PUNCT
dpc-1620	142	21	and	and	CCONJ
dpc-1620	142	22	huddle	huddle	NOUN
dpc-1620	142	23	collagen	collagen	NOUN
dpc-1620	143	1	[	[	X
dpc-1620	143	2	19	19	NUM
dpc-1620	143	3	-	-	SYM
dpc-1620	143	4	21	21	NUM
dpc-1620	143	5	]	]	PUNCT
dpc-1620	143	6	.	.	PUNCT
dpc-1620	144	1	from	from	ADP
dpc-1620	144	2	skin	skin	NOUN
dpc-1620	144	3	aging	aging	NOUN
dpc-1620	144	4	to	to	ADP
dpc-1620	144	5	skin	skin	NOUN
dpc-1620	144	6	cancer	cancer	NOUN
dpc-1620	144	7	skin	skin	NOUN
dpc-1620	144	8	variations	variation	NOUN
dpc-1620	144	9	occurring	occur	VERB
dpc-1620	144	10	with	with	ADP
dpc-1620	144	11	passing	pass	VERB
dpc-1620	144	12	years	year	NOUN
dpc-1620	144	13	have	have	AUX
dpc-1620	144	14	been	be	AUX
dpc-1620	144	15	related	relate	VERB
dpc-1620	144	16	to	to	ADP
dpc-1620	144	17	skin	skin	NOUN
dpc-1620	144	18	cancer	cancer	NOUN
dpc-1620	144	19	development	development	NOUN
dpc-1620	144	20	and	and	CCONJ
dpc-1620	144	21	progression	progression	NOUN
dpc-1620	144	22	[	[	X
dpc-1620	144	23	4,30,31	4,30,31	NUM
dpc-1620	144	24	]	]	PUNCT
dpc-1620	144	25	.	.	PUNCT
dpc-1620	145	1	interestingly	interestingly	ADV
dpc-1620	145	2	,	,	PUNCT
dpc-1620	145	3	rcm	rcm	PROPN
dpc-1620	145	4	enables	enable	VERB
dpc-1620	145	5	the	the	DET
dpc-1620	145	6	visualization	visualization	NOUN
dpc-1620	145	7	of	of	ADP
dpc-1620	145	8	features	feature	NOUN
dpc-1620	145	9	shared	share	VERB
dpc-1620	145	10	by	by	ADP
dpc-1620	145	11	aged	aged	ADJ
dpc-1620	145	12	skin	skin	NOUN
dpc-1620	145	13	and	and	CCONJ
dpc-1620	145	14	skin	skin	NOUN
dpc-1620	145	15	cancer	cancer	NOUN
dpc-1620	145	16	at	at	ADP
dpc-1620	145	17	both	both	CCONJ
dpc-1620	145	18	the	the	DET
dpc-1620	145	19	epidermal	epidermal	ADJ
dpc-1620	145	20	level	level	NOUN
dpc-1620	145	21	,	,	PUNCT
dpc-1620	145	22	such	such	ADJ
dpc-1620	145	23	as	as	ADP
dpc-1620	145	24	atypical	atypical	ADJ
dpc-1620	145	25	cells	cell	NOUN
dpc-1620	145	26	or	or	CCONJ
dpc-1620	145	27	atypical	atypical	ADJ
dpc-1620	145	28	honeycomb	honeycomb	NOUN
dpc-1620	145	29	pattern	pattern	NOUN
dpc-1620	145	30	,	,	PUNCT
dpc-1620	145	31	and	and	CCONJ
dpc-1620	145	32	the	the	DET
dpc-1620	145	33	dermal	dermal	ADJ
dpc-1620	145	34	level	level	NOUN
dpc-1620	145	35	,	,	PUNCT
dpc-1620	145	36	such	such	ADJ
dpc-1620	145	37	as	as	ADP
dpc-1620	145	38	dilated	dilated	ADJ
dpc-1620	145	39	vessels	vessel	NOUN
dpc-1620	145	40	or	or	CCONJ
dpc-1620	145	41	collagen	collagen	NOUN
dpc-1620	145	42	variations	variation	NOUN
dpc-1620	145	43	.	.	PUNCT
dpc-1620	146	1	at	at	ADP
dpc-1620	146	2	the	the	DET
dpc-1620	146	3	epidermal	epidermal	ADJ
dpc-1620	146	4	level	level	NOUN
dpc-1620	146	5	,	,	PUNCT
dpc-1620	146	6	a	a	DET
dpc-1620	146	7	focal	focal	ADJ
dpc-1620	146	8	,	,	PUNCT
dpc-1620	146	9	atypical	atypical	ADJ
dpc-1620	146	10	honeycomb	honeycomb	NOUN
dpc-1620	146	11	pattern	pattern	NOUN
dpc-1620	146	12	related	relate	VERB
dpc-1620	146	13	to	to	ADP
dpc-1620	146	14	chronic	chronic	ADJ
dpc-1620	146	15	sun	sun	NOUN
dpc-1620	146	16	exposure	exposure	NOUN
dpc-1620	146	17	is	be	AUX
dpc-1620	146	18	typically	typically	ADV
dpc-1620	146	19	observed	observe	VERB
dpc-1620	146	20	in	in	ADP
dpc-1620	146	21	actinic	actinic	ADJ
dpc-1620	146	22	keratosis	keratosis	NOUN
dpc-1620	146	23	(	(	PUNCT
dpc-1620	146	24	figure	figure	NOUN
dpc-1620	146	25	4	4	NUM
dpc-1620	146	26	,	,	PUNCT
dpc-1620	146	27	a	a	PRON
dpc-1620	146	28	and	and	CCONJ
dpc-1620	146	29	b	b	NOUN
dpc-1620	146	30	)	)	PUNCT
dpc-1620	146	31	,	,	PUNCT
dpc-1620	146	32	while	while	SCONJ
dpc-1620	146	33	a	a	DET
dpc-1620	146	34	disarranged	disarrange	VERB
dpc-1620	146	35	epidermal	epidermal	ADJ
dpc-1620	146	36	pattern	pattern	NOUN
dpc-1620	146	37	and	and	CCONJ
dpc-1620	146	38	ulceration	ulceration	NOUN
dpc-1620	146	39	are	be	AUX
dpc-1620	146	40	commonly	commonly	ADV
dpc-1620	146	41	observed	observe	VERB
dpc-1620	146	42	in	in	ADP
dpc-1620	146	43	scc	scc	PROPN
dpc-1620	147	1	[	[	X
dpc-1620	147	2	9,32	9,32	X
dpc-1620	147	3	]	]	PUNCT
dpc-1620	147	4	.	.	PUNCT
dpc-1620	148	1	additionally	additionally	ADV
dpc-1620	148	2	,	,	PUNCT
dpc-1620	148	3	since	since	SCONJ
dpc-1620	148	4	melanocytes	melanocyte	NOUN
dpc-1620	148	5	are	be	AUX
dpc-1620	148	6	not	not	PART
dpc-1620	148	7	visible	visible	ADJ
dpc-1620	148	8	in	in	ADP
dpc-1620	148	9	healthy	healthy	ADJ
dpc-1620	148	10	skin	skin	NOUN
dpc-1620	148	11	,	,	PUNCT
dpc-1620	148	12	the	the	DET
dpc-1620	148	13	identification	identification	NOUN
dpc-1620	148	14	of	of	ADP
dpc-1620	148	15	atypical	atypical	ADJ
dpc-1620	148	16	cells	cell	NOUN
dpc-1620	148	17	or	or	CCONJ
dpc-1620	148	18	nests	nest	NOUN
dpc-1620	148	19	(	(	PUNCT
dpc-1620	148	20	referred	refer	VERB
dpc-1620	148	21	to	to	ADP
dpc-1620	148	22	melanocytes	melanocyte	NOUN
dpc-1620	148	23	)	)	PUNCT
dpc-1620	148	24	with	with	SCONJ
dpc-1620	148	25	rcm	rcm	PROPN
dpc-1620	148	26	contributes	contribute	VERB
dpc-1620	148	27	to	to	ADP
dpc-1620	148	28	the	the	DET
dpc-1620	148	29	differential	differential	ADJ
dpc-1620	148	30	diagnosis	diagnosis	NOUN
dpc-1620	148	31	of	of	ADP
dpc-1620	148	32	lm	lm	PROPN
dpc-1620	148	33	/	/	SYM
dpc-1620	148	34	lmm	lmm	PROPN
dpc-1620	148	35	(	(	PUNCT
dpc-1620	148	36	figure	figure	NOUN
dpc-1620	148	37	4	4	NUM
dpc-1620	148	38	,	,	PUNCT
dpc-1620	148	39	c	c	NOUN
dpc-1620	148	40	and	and	CCONJ
dpc-1620	148	41	d	d	NOUN
dpc-1620	148	42	)	)	PUNCT
dpc-1620	148	43	with	with	ADP
dpc-1620	148	44	other	other	ADJ
dpc-1620	148	45	pigmented	pigment	VERB
dpc-1620	148	46	macules	macule	NOUN
dpc-1620	148	47	of	of	ADP
dpc-1620	148	48	the	the	DET
dpc-1620	148	49	face	face	NOUN
dpc-1620	149	1	[	[	X
dpc-1620	149	2	33	33	NUM
dpc-1620	149	3	]	]	PUNCT
dpc-1620	149	4	.	.	PUNCT
dpc-1620	150	1	at	at	ADP
dpc-1620	150	2	the	the	DET
dpc-1620	150	3	dermal	dermal	ADJ
dpc-1620	150	4	level	level	NOUN
dpc-1620	150	5	,	,	PUNCT
dpc-1620	150	6	dilated	dilated	ADJ
dpc-1620	150	7	vessels	vessel	NOUN
dpc-1620	150	8	may	may	AUX
dpc-1620	150	9	be	be	AUX
dpc-1620	150	10	observed	observe	VERB
dpc-1620	150	11	in	in	ADP
dpc-1620	150	12	nmsc	nmsc	NOUN
dpc-1620	150	13	,	,	PUNCT
dpc-1620	150	14	where	where	SCONJ
dpc-1620	150	15	they	they	PRON
dpc-1620	150	16	are	be	AUX
dpc-1620	150	17	typically	typically	ADV
dpc-1620	150	18	horizontal	horizontal	ADJ
dpc-1620	150	19	and	and	CCONJ
dpc-1620	150	20	branching	branch	VERB
dpc-1620	150	21	,	,	PUNCT
dpc-1620	150	22	surrounding	surround	VERB
dpc-1620	150	23	the	the	DET
dpc-1620	150	24	tumor	tumor	NOUN
dpc-1620	150	25	island	island	NOUN
dpc-1620	150	26	in	in	ADP
dpc-1620	150	27	bcc	bcc	PROPN
dpc-1620	150	28	and	and	CCONJ
dpc-1620	150	29	more	more	ADV
dpc-1620	150	30	irregular	irregular	ADJ
dpc-1620	150	31	in	in	ADP
dpc-1620	150	32	scc	scc	NOUN
dpc-1620	151	1	[	[	X
dpc-1620	151	2	34,35	34,35	NOUN
dpc-1620	151	3	]	]	PUNCT
dpc-1620	151	4	.	.	PUNCT
dpc-1620	152	1	some	some	DET
dpc-1620	152	2	other	other	ADJ
dpc-1620	152	3	morphologic	morphologic	ADJ
dpc-1620	152	4	variations	variation	NOUN
dpc-1620	152	5	at	at	ADP
dpc-1620	152	6	the	the	DET
dpc-1620	152	7	dermal	dermal	ADJ
dpc-1620	152	8	level	level	NOUN
dpc-1620	152	9	include	include	VERB
dpc-1620	152	10	bundles	bundle	NOUN
dpc-1620	152	11	of	of	ADP
dpc-1620	152	12	lace	lace	NOUN
dpc-1620	152	13	-	-	PUNCT
dpc-1620	152	14	like	like	ADJ
dpc-1620	152	15	collagen	collagen	NOUN
dpc-1620	152	16	in	in	ADP
dpc-1620	152	17	actinic	actinic	ADJ
dpc-1620	152	18	keratosis	keratosis	NOUN
dpc-1620	152	19	and	and	CCONJ
dpc-1620	152	20	scc	scc	NOUN
dpc-1620	153	1	[	[	X
dpc-1620	153	2	36	36	NUM
dpc-1620	153	3	]	]	PUNCT
dpc-1620	153	4	and	and	CCONJ
dpc-1620	153	5	collagen	collagen	NOUN
dpc-1620	153	6	bundles	bundle	NOUN
dpc-1620	153	7	surrounding	surround	VERB
dpc-1620	153	8	dark	dark	ADJ
dpc-1620	153	9	silhouette	silhouette	NOUN
dpc-1620	153	10	in	in	ADP
dpc-1620	153	11	hypopigmented	hypopigmente	VERB
dpc-1620	153	12	bcc	bcc	PROPN
dpc-1620	154	1	[	[	X
dpc-1620	154	2	37,38	37,38	NOUN
dpc-1620	154	3	]	]	PUNCT
dpc-1620	154	4	.	.	PUNCT
dpc-1620	155	1	interestingly	interestingly	ADV
dpc-1620	155	2	,	,	PUNCT
dpc-1620	155	3	fewer	few	ADJ
dpc-1620	155	4	curled	curled	ADJ
dpc-1620	155	5	fibers	fiber	NOUN
dpc-1620	155	6	,	,	PUNCT
dpc-1620	155	7	corresponding	correspond	VERB
dpc-1620	155	8	to	to	ADP
dpc-1620	155	9	solar	solar	ADJ
dpc-1620	155	10	elastosis	elastosis	NOUN
dpc-1620	155	11	,	,	PUNCT
dpc-1620	155	12	were	be	AUX
dpc-1620	155	13	observed	observe	VERB
dpc-1620	155	14	in	in	ADP
dpc-1620	155	15	subjects	subject	NOUN
dpc-1620	155	16	with	with	ADP
dpc-1620	155	17	atrophic	atrophic	ADJ
dpc-1620	155	18	photoaging	photoaging	NOUN
dpc-1620	155	19	(	(	PUNCT
dpc-1620	155	20	more	more	ADV
dpc-1620	155	21	prone	prone	ADJ
dpc-1620	155	22	to	to	ADP
dpc-1620	155	23	skin	skin	NOUN
dpc-1620	155	24	cancer	cancer	NOUN
dpc-1620	155	25	)	)	PUNCT
dpc-1620	155	26	than	than	ADP
dpc-1620	155	27	in	in	ADP
dpc-1620	155	28	patients	patient	NOUN
dpc-1620	155	29	with	with	ADP
dpc-1620	155	30	hypertrophic	hypertrophic	ADJ
dpc-1620	155	31	photoaging	photoaging	NOUN
dpc-1620	155	32	[	[	X
dpc-1620	155	33	4,13,23	4,13,23	PROPN
dpc-1620	155	34	]	]	PUNCT
dpc-1620	155	35	.	.	PUNCT
dpc-1620	156	1	therefore	therefore	ADV
dpc-1620	156	2	,	,	PUNCT
dpc-1620	156	3	the	the	DET
dpc-1620	156	4	lack	lack	NOUN
dpc-1620	156	5	of	of	ADP
dpc-1620	156	6	solar	solar	ADJ
dpc-1620	156	7	elastosis	elastosis	NOUN
dpc-1620	156	8	in	in	ADP
dpc-1620	156	9	subjects	subject	NOUN
dpc-1620	156	10	with	with	ADP
dpc-1620	156	11	atrophic	atrophic	ADJ
dpc-1620	156	12	photoaging	photoaging	NOUN
dpc-1620	156	13	seems	seem	VERB
dpc-1620	156	14	to	to	PART
dpc-1620	156	15	contribute	contribute	VERB
dpc-1620	156	16	to	to	ADP
dpc-1620	156	17	increased	increase	VERB
dpc-1620	156	18	collagen	collagen	NOUN
dpc-1620	156	19	fragmentation	fragmentation	NOUN
dpc-1620	156	20	,	,	PUNCT
dpc-1620	156	21	which	which	PRON
dpc-1620	156	22	modifies	modify	VERB
dpc-1620	156	23	the	the	DET
dpc-1620	156	24	dermal	dermal	ADJ
dpc-1620	156	25	microenvironment	microenvironment	NOUN
dpc-1620	156	26	[	[	X
dpc-1620	156	27	4	4	NUM
dpc-1620	156	28	]	]	PUNCT
dpc-1620	156	29	.	.	PUNCT
dpc-1620	157	1	additionally	additionally	ADV
dpc-1620	157	2	,	,	PUNCT
dpc-1620	157	3	a	a	DET
dpc-1620	157	4	lack	lack	NOUN
dpc-1620	157	5	of	of	ADP
dpc-1620	157	6	solar	solar	ADJ
dpc-1620	157	7	elastosis	elastosis	NOUN
dpc-1620	157	8	has	have	AUX
dpc-1620	157	9	been	be	AUX
dpc-1620	157	10	described	describe	VERB
dpc-1620	157	11	in	in	ADP
dpc-1620	157	12	the	the	DET
dpc-1620	157	13	adjacent	adjacent	ADJ
dpc-1620	157	14	skin	skin	NOUN
dpc-1620	157	15	of	of	ADP
dpc-1620	157	16	melanomas	melanomas	NOUN
dpc-1620	157	17	harboring	harboring	NOUN
dpc-1620	157	18	braf	braf	NOUN
dpc-1620	157	19	mutations	mutation	NOUN
dpc-1620	157	20	,	,	PUNCT
dpc-1620	157	21	which	which	PRON
dpc-1620	157	22	are	be	AUX
dpc-1620	157	23	a	a	DET
dpc-1620	157	24	common	common	ADJ
dpc-1620	157	25	finding	finding	NOUN
dpc-1620	157	26	in	in	ADP
dpc-1620	157	27	melanoma	melanoma	NOUN
dpc-1620	157	28	[	[	X
dpc-1620	157	29	39	39	NUM
dpc-1620	157	30	]	]	PUNCT
dpc-1620	157	31	.	.	PUNCT
dpc-1620	158	1	the	the	DET
dpc-1620	158	2	correlation	correlation	NOUN
dpc-1620	158	3	between	between	ADP
dpc-1620	158	4	specific	specific	ADJ
dpc-1620	158	5	epidermal	epidermal	ADJ
dpc-1620	158	6	and	and	CCONJ
dpc-1620	158	7	dermal	dermal	ADJ
dpc-1620	158	8	characteristics	characteristic	NOUN
dpc-1620	158	9	and	and	CCONJ
dpc-1620	158	10	skin	skin	NOUN
dpc-1620	158	11	photoaging	photoaging	NOUN
dpc-1620	158	12	confirms	confirm	VERB
dpc-1620	158	13	that	that	SCONJ
dpc-1620	158	14	uv	uv	NOUN
dpc-1620	158	15	irradiation	irradiation	NOUN
dpc-1620	158	16	contributes	contribute	VERB
dpc-1620	158	17	to	to	ADP
dpc-1620	158	18	cellular	cellular	ADJ
dpc-1620	158	19	atypia	atypia	NOUN
dpc-1620	158	20	;	;	PUNCT
dpc-1620	158	21	moreover	moreover	ADV
dpc-1620	158	22	,	,	PUNCT
dpc-1620	158	23	it	it	PRON
dpc-1620	158	24	seems	seem	VERB
dpc-1620	158	25	to	to	PART
dpc-1620	158	26	support	support	VERB
dpc-1620	158	27	the	the	DET
dpc-1620	158	28	notion	notion	NOUN
dpc-1620	158	29	that	that	SCONJ
dpc-1620	158	30	the	the	DET
dpc-1620	158	31	dermal	dermal	ADJ
dpc-1620	158	32	microenvironment	microenvironment	NOUN
dpc-1620	158	33	is	be	AUX
dpc-1620	158	34	an	an	DET
dpc-1620	158	35	active	active	ADJ
dpc-1620	158	36	participant	participant	NOUN
dpc-1620	158	37	in	in	ADP
dpc-1620	158	38	the	the	DET
dpc-1620	158	39	formation	formation	NOUN
dpc-1620	158	40	of	of	ADP
dpc-1620	158	41	skin	skin	NOUN
dpc-1620	158	42	cancer	cancer	NOUN
dpc-1620	158	43	[	[	X
dpc-1620	158	44	4	4	NUM
dpc-1620	158	45	]	]	PUNCT
dpc-1620	158	46	.	.	PUNCT
dpc-1620	159	1	accordingly	accordingly	ADV
dpc-1620	159	2	,	,	PUNCT
dpc-1620	159	3	increased	increase	VERB
dpc-1620	159	4	vascularization	vascularization	NOUN
dpc-1620	159	5	has	have	AUX
dpc-1620	159	6	been	be	AUX
dpc-1620	159	7	implicated	implicate	VERB
dpc-1620	159	8	in	in	ADP
dpc-1620	159	9	skin	skin	NOUN
dpc-1620	159	10	cancer	cancer	NOUN
dpc-1620	159	11	development	development	NOUN
dpc-1620	159	12	because	because	SCONJ
dpc-1620	159	13	it	it	PRON
dpc-1620	159	14	provides	provide	VERB
dpc-1620	159	15	an	an	DET
dpc-1620	159	16	enriched	enriched	ADJ
dpc-1620	159	17	microenvironment	microenvironment	NOUN
dpc-1620	159	18	for	for	ADP
dpc-1620	159	19	tumor	tumor	NOUN
dpc-1620	159	20	growth	growth	NOUN
dpc-1620	160	1	[	[	X
dpc-1620	160	2	4,30,31	4,30,31	NUM
dpc-1620	160	3	]	]	PUNCT
dpc-1620	160	4	.	.	PUNCT
dpc-1620	161	1	the	the	DET
dpc-1620	161	2	lack	lack	NOUN
dpc-1620	161	3	of	of	ADP
dpc-1620	161	4	solar	solar	ADJ
dpc-1620	161	5	elastosis	elastosis	NOUN
dpc-1620	161	6	,	,	PUNCT
dpc-1620	161	7	observed	observe	VERB
dpc-1620	161	8	in	in	ADP
dpc-1620	161	9	subjects	subject	NOUN
dpc-1620	161	10	with	with	ADP
dpc-1620	161	11	atrophic	atrophic	ADJ
dpc-1620	161	12	photoaging	photoaging	NOUN
dpc-1620	161	13	and	and	CCONJ
dpc-1620	161	14	in	in	ADP
dpc-1620	161	15	the	the	DET
dpc-1620	161	16	surrounding	surround	VERB
dpc-1620	161	17	skin	skin	NOUN
dpc-1620	161	18	of	of	ADP
dpc-1620	161	19	melanomas	melanomas	NOUN
dpc-1620	161	20	,	,	PUNCT
dpc-1620	161	21	has	have	AUX
dpc-1620	161	22	been	be	AUX
dpc-1620	161	23	hypothesized	hypothesize	VERB
dpc-1620	161	24	as	as	ADP
dpc-1620	161	25	a	a	DET
dpc-1620	161	26	risk	risk	NOUN
dpc-1620	161	27	factor	factor	NOUN
dpc-1620	161	28	for	for	ADP
dpc-1620	161	29	the	the	DET
dpc-1620	161	30	growth	growth	NOUN
dpc-1620	161	31	and	and	CCONJ
dpc-1620	161	32	expansion	expansion	NOUN
dpc-1620	161	33	of	of	ADP
dpc-1620	161	34	skin	skin	NOUN
dpc-1620	161	35	tumors	tumor	NOUN
dpc-1620	161	36	[	[	X
dpc-1620	161	37	4	4	NUM
dpc-1620	161	38	]	]	PUNCT
dpc-1620	161	39	.	.	PUNCT
dpc-1620	162	1	other	other	ADJ
dpc-1620	162	2	mechanochemical	mechanochemical	ADJ
dpc-1620	162	3	interactions	interaction	NOUN
dpc-1620	162	4	between	between	ADP
dpc-1620	162	5	aged	aged	ADJ
dpc-1620	162	6	skin	skin	NOUN
dpc-1620	162	7	and	and	CCONJ
dpc-1620	162	8	tumor	tumor	NOUN
dpc-1620	162	9	,	,	PUNCT
dpc-1620	162	10	which	which	PRON
dpc-1620	162	11	may	may	AUX
dpc-1620	162	12	affect	affect	VERB
dpc-1620	162	13	metastasis	metastasis	NOUN
dpc-1620	162	14	,	,	PUNCT
dpc-1620	162	15	have	have	AUX
dpc-1620	162	16	also	also	ADV
dpc-1620	162	17	been	be	AUX
dpc-1620	162	18	described	describe	VERB
dpc-1620	162	19	[	[	X
dpc-1620	162	20	40	40	NUM
dpc-1620	162	21	]	]	PUNCT
dpc-1620	162	22	.	.	PUNCT
dpc-1620	163	1	interestingly	interestingly	ADV
dpc-1620	163	2	,	,	PUNCT
dpc-1620	163	3	a	a	DET
dpc-1620	163	4	different	different	ADJ
dpc-1620	163	5	collagen	collagen	NOUN
dpc-1620	163	6	morphology	morphology	NOUN
dpc-1620	163	7	and	and	CCONJ
dpc-1620	163	8	increased	increase	VERB
dpc-1620	163	9	vascularization	vascularization	NOUN
dpc-1620	163	10	have	have	AUX
dpc-1620	163	11	been	be	AUX
dpc-1620	163	12	observed	observe	VERB
dpc-1620	163	13	in	in	ADP
dpc-1620	163	14	subjects	subject	NOUN
dpc-1620	163	15	with	with	ADP
dpc-1620	163	16	atrophic	atrophic	ADJ
dpc-1620	163	17	photoaging	photoaging	NOUN
dpc-1620	163	18	,	,	PUNCT
dpc-1620	163	19	who	who	PRON
dpc-1620	163	20	are	be	AUX
dpc-1620	163	21	more	more	ADV
dpc-1620	163	22	likely	likely	ADJ
dpc-1620	163	23	to	to	PART
dpc-1620	163	24	have	have	VERB
dpc-1620	163	25	skin	skin	NOUN
dpc-1620	163	26	cancer	cancer	NOUN
dpc-1620	163	27	and	and	CCONJ
dpc-1620	163	28	to	to	PART
dpc-1620	163	29	carry	carry	VERB
dpc-1620	163	30	melanocortin-1	melanocortin-1	NUM
dpc-1620	163	31	receptor	receptor	NOUN
dpc-1620	163	32	gene	gene	NOUN
dpc-1620	163	33	(	(	PUNCT
dpc-1620	163	34	mc1r	mc1r	PROPN
dpc-1620	163	35	)	)	PUNCT
dpc-1620	163	36	polymorphisms	polymorphism	NOUN
dpc-1620	163	37	[	[	X
dpc-1620	163	38	4,22,23	4,22,23	NUM
dpc-1620	163	39	]	]	PUNCT
dpc-1620	163	40	.	.	PUNCT
dpc-1620	164	1	mc1r	mc1r	PROPN
dpc-1620	164	2	polymorphisms	polymorphism	NOUN
dpc-1620	164	3	have	have	AUX
dpc-1620	164	4	been	be	AUX
dpc-1620	164	5	associated	associate	VERB
dpc-1620	164	6	with	with	ADP
dpc-1620	164	7	the	the	DET
dpc-1620	164	8	red	red	ADJ
dpc-1620	164	9	hair	hair	NOUN
dpc-1620	164	10	phenotype	phenotype	NOUN
dpc-1620	164	11	,	,	PUNCT
dpc-1620	164	12	characterized	characterize	VERB
dpc-1620	164	13	by	by	ADP
dpc-1620	164	14	red	red	ADJ
dpc-1620	164	15	hair	hair	NOUN
dpc-1620	164	16	,	,	PUNCT
dpc-1620	164	17	freckles	freckle	NOUN
dpc-1620	164	18	,	,	PUNCT
dpc-1620	164	19	light	light	ADJ
dpc-1620	164	20	skin	skin	NOUN
dpc-1620	164	21	and	and	CCONJ
dpc-1620	164	22	poor	poor	ADJ
dpc-1620	164	23	tanning	tanning	NOUN
dpc-1620	164	24	.	.	PUNCT
dpc-1620	165	1	however	however	ADV
dpc-1620	165	2	,	,	PUNCT
dpc-1620	165	3	a	a	DET
dpc-1620	165	4	different	different	ADJ
dpc-1620	165	5	mc1r	mc1r	NOUN
dpc-1620	165	6	genotype	genotype	NOUN
dpc-1620	165	7	might	might	AUX
dpc-1620	165	8	express	express	VERB
dpc-1620	165	9	different	different	ADJ
dpc-1620	165	10	phenotypes	phenotype	NOUN
dpc-1620	165	11	,	,	PUNCT
dpc-1620	165	12	sharing	share	VERB
dpc-1620	165	13	the	the	DET
dpc-1620	165	14	poor	poor	ADJ
dpc-1620	165	15	tanning	tanning	NOUN
dpc-1620	165	16	ability	ability	NOUN
dpc-1620	165	17	and	and	CCONJ
dpc-1620	165	18	tendency	tendency	NOUN
dpc-1620	165	19	to	to	PART
dpc-1620	165	20	have	have	AUX
dpc-1620	165	21	freckles	freckle	NOUN
dpc-1620	165	22	and	and	CCONJ
dpc-1620	165	23	light	light	ADJ
dpc-1620	165	24	skin	skin	NOUN
dpc-1620	165	25	[	[	X
dpc-1620	165	26	41	41	NUM
dpc-1620	165	27	]	]	PUNCT
dpc-1620	165	28	.	.	PUNCT
dpc-1620	166	1	despite	despite	SCONJ
dpc-1620	166	2	this	this	DET
dpc-1620	166	3	phenotype	phenotype	NOUN
dpc-1620	166	4	,	,	PUNCT
dpc-1620	166	5	carrying	carry	VERB
dpc-1620	166	6	specific	specific	ADJ
dpc-1620	166	7	mc1r	mc1r	NOUN
dpc-1620	166	8	polymorphisms	polymorphism	NOUN
dpc-1620	166	9	increases	increase	VERB
dpc-1620	166	10	the	the	DET
dpc-1620	166	11	risk	risk	NOUN
dpc-1620	166	12	of	of	ADP
dpc-1620	166	13	melanoma	melanoma	NOUN
dpc-1620	166	14	and	and	CCONJ
dpc-1620	166	15	nmsc	nmsc	NOUN
dpc-1620	167	1	[	[	X
dpc-1620	167	2	42,43	42,43	NOUN
dpc-1620	167	3	]	]	X
dpc-1620	167	4	.	.	PUNCT
dpc-1620	168	1	this	this	DET
dpc-1620	168	2	finding	finding	NOUN
dpc-1620	168	3	seems	seem	VERB
dpc-1620	168	4	to	to	PART
dpc-1620	168	5	provide	provide	VERB
dpc-1620	168	6	new	new	ADJ
dpc-1620	168	7	insights	insight	NOUN
dpc-1620	168	8	into	into	ADP
dpc-1620	168	9	the	the	DET
dpc-1620	168	10	relation	relation	NOUN
dpc-1620	168	11	between	between	ADP
dpc-1620	168	12	skin	skin	NOUN
dpc-1620	168	13	photoaging	photoage	VERB
dpc-1620	168	14	type	type	NOUN
dpc-1620	168	15	and	and	CCONJ
dpc-1620	168	16	the	the	DET
dpc-1620	168	17	susceptibility	susceptibility	NOUN
dpc-1620	168	18	to	to	ADP
dpc-1620	168	19	skin	skin	NOUN
dpc-1620	168	20	cancer	cancer	NOUN
dpc-1620	168	21	,	,	PUNCT
dpc-1620	168	22	but	but	CCONJ
dpc-1620	168	23	further	further	ADJ
dpc-1620	168	24	studies	study	NOUN
dpc-1620	168	25	are	be	AUX
dpc-1620	168	26	needed	need	VERB
dpc-1620	168	27	to	to	PART
dpc-1620	168	28	explain	explain	VERB
dpc-1620	168	29	the	the	DET
dpc-1620	168	30	complex	complex	ADJ
dpc-1620	168	31	phenomena	phenomenon	NOUN
dpc-1620	168	32	leading	lead	VERB
dpc-1620	168	33	from	from	ADP
dpc-1620	168	34	skin	skin	NOUN
dpc-1620	168	35	aging	aging	NOUN
dpc-1620	168	36	to	to	ADP
dpc-1620	168	37	tumor	tumor	NOUN
dpc-1620	168	38	development	development	NOUN
dpc-1620	168	39	and	and	CCONJ
dpc-1620	168	40	progression	progression	NOUN
dpc-1620	168	41	.	.	PUNCT
dpc-1620	169	1	conclusions	conclusion	NOUN
dpc-1620	169	2	rcm	rcm	PROPN
dpc-1620	169	3	facilitates	facilitate	VERB
dpc-1620	169	4	the	the	DET
dpc-1620	169	5	identification	identification	NOUN
dpc-1620	169	6	of	of	ADP
dpc-1620	169	7	in	in	ADP
dpc-1620	169	8	vivo	vivo	ADJ
dpc-1620	169	9	features	feature	NOUN
dpc-1620	169	10	of	of	ADP
dpc-1620	169	11	healthy	healthy	ADJ
dpc-1620	169	12	skin	skin	NOUN
dpc-1620	169	13	and	and	CCONJ
dpc-1620	169	14	the	the	DET
dpc-1620	169	15	recognition	recognition	NOUN
dpc-1620	169	16	of	of	ADP
dpc-1620	169	17	skin	skin	NOUN
dpc-1620	169	18	aging	age	VERB
dpc-1620	169	19	variations	variation	NOUN
dpc-1620	169	20	at	at	ADP
dpc-1620	169	21	different	different	ADJ
dpc-1620	169	22	skin	skin	NOUN
dpc-1620	169	23	layers	layer	NOUN
dpc-1620	169	24	,	,	PUNCT
dpc-1620	169	25	with	with	ADP
dpc-1620	169	26	histopathologic	histopathologic	ADJ
dpc-1620	169	27	resolution	resolution	NOUN
dpc-1620	169	28	.	.	PUNCT
dpc-1620	170	1	skin	skin	NOUN
dpc-1620	170	2	aging	age	VERB
dpc-1620	170	3	changes	change	NOUN
dpc-1620	170	4	have	have	AUX
dpc-1620	170	5	been	be	AUX
dpc-1620	170	6	shown	show	VERB
dpc-1620	170	7	to	to	PART
dpc-1620	170	8	correlate	correlate	VERB
dpc-1620	170	9	with	with	ADP
dpc-1620	170	10	skin	skin	NOUN
dpc-1620	170	11	cancer	cancer	NOUN
dpc-1620	170	12	development	development	NOUN
dpc-1620	170	13	and	and	CCONJ
dpc-1620	170	14	progression	progression	NOUN
dpc-1620	170	15	.	.	PUNCT
dpc-1620	171	1	interestingly	interestingly	ADV
dpc-1620	171	2	,	,	PUNCT
dpc-1620	171	3	rcm	rcm	PROPN
dpc-1620	171	4	enables	enable	VERB
dpc-1620	171	5	the	the	DET
dpc-1620	171	6	visualization	visualization	NOUN
dpc-1620	171	7	of	of	ADP
dpc-1620	171	8	features	feature	NOUN
dpc-1620	171	9	shared	share	VERB
dpc-1620	171	10	by	by	ADP
dpc-1620	171	11	aged	aged	ADJ
dpc-1620	171	12	skin	skin	NOUN
dpc-1620	171	13	and	and	CCONJ
dpc-1620	171	14	skin	skin	NOUN
dpc-1620	171	15	cancer	cancer	NOUN
dpc-1620	171	16	,	,	PUNCT
dpc-1620	171	17	at	at	ADP
dpc-1620	171	18	both	both	CCONJ
dpc-1620	171	19	the	the	DET
dpc-1620	171	20	epidermal	epidermal	ADJ
dpc-1620	171	21	level	level	NOUN
dpc-1620	171	22	(	(	PUNCT
dpc-1620	171	23	eg	eg	NOUN
dpc-1620	171	24	,	,	PUNCT
dpc-1620	171	25	atypical	atypical	ADJ
dpc-1620	171	26	cells	cell	NOUN
dpc-1620	171	27	or	or	CCONJ
dpc-1620	171	28	atypical	atypical	ADJ
dpc-1620	171	29	honeycomb	honeycomb	NOUN
dpc-1620	171	30	pattern	pattern	NOUN
dpc-1620	171	31	)	)	PUNCT
dpc-1620	171	32	and	and	CCONJ
dpc-1620	171	33	the	the	DET
dpc-1620	171	34	dermal	dermal	ADJ
dpc-1620	171	35	level	level	NOUN
dpc-1620	171	36	(	(	PUNCT
dpc-1620	171	37	eg	eg	NOUN
dpc-1620	171	38	,	,	PUNCT
dpc-1620	171	39	dilated	dilated	ADJ
dpc-1620	171	40	vessels	vessel	NOUN
dpc-1620	171	41	or	or	CCONJ
dpc-1620	171	42	collagen	collagen	NOUN
dpc-1620	171	43	variations	variation	NOUN
dpc-1620	171	44	)	)	PUNCT
dpc-1620	171	45	.	.	PUNCT
dpc-1620	172	1	however	however	ADV
dpc-1620	172	2	,	,	PUNCT
dpc-1620	172	3	the	the	DET
dpc-1620	172	4	mechanism	mechanism	NOUN
dpc-1620	172	5	that	that	PRON
dpc-1620	172	6	links	link	VERB
dpc-1620	172	7	morphological	morphological	ADJ
dpc-1620	172	8	variations	variation	NOUN
dpc-1620	172	9	in	in	ADP
dpc-1620	172	10	aging	age	VERB
dpc-1620	172	11	skin	skin	NOUN
dpc-1620	172	12	to	to	ADP
dpc-1620	172	13	skin	skin	NOUN
dpc-1620	172	14	cancer	cancer	NOUN
dpc-1620	172	15	needs	need	VERB
dpc-1620	172	16	further	further	ADJ
dpc-1620	172	17	investigation	investigation	NOUN
dpc-1620	172	18	.	.	PUNCT
dpc-1620	173	1	references	reference	NOUN
dpc-1620	173	2	1	1	NUM
dpc-1620	173	3	.	.	PUNCT
dpc-1620	174	1	longo	longo	PROPN
dpc-1620	174	2	c	c	PROPN
dpc-1620	174	3	,	,	PUNCT
dpc-1620	174	4	galimberti	galimberti	PROPN
dpc-1620	174	5	m	m	PROPN
dpc-1620	174	6	,	,	PUNCT
dpc-1620	174	7	de	de	X
dpc-1620	174	8	pace	pace	NOUN
dpc-1620	174	9	b	b	NOUN
dpc-1620	174	10	,	,	PUNCT
dpc-1620	174	11	pellacani	pellacani	VERB
dpc-1620	174	12	g	g	NOUN
dpc-1620	174	13	,	,	PUNCT
dpc-1620	174	14	bencini	bencini	PROPN
dpc-1620	174	15	pl	pl	PROPN
dpc-1620	174	16	.	.	PROPN
dpc-1620	174	17	laser	laser	PROPN
dpc-1620	174	18	skin	skin	NOUN
dpc-1620	174	19	rejuvenation	rejuvenation	NOUN
dpc-1620	174	20	:	:	PUNCT
dpc-1620	174	21	epidermal	epidermal	ADJ
dpc-1620	174	22	changes	change	NOUN
dpc-1620	174	23	and	and	CCONJ
dpc-1620	174	24	collagen	collagen	NOUN
dpc-1620	174	25	remodeling	remodeling	NOUN
dpc-1620	174	26	evaluated	evaluate	VERB
dpc-1620	174	27	by	by	ADP
dpc-1620	174	28	in	in	ADP
dpc-1620	174	29	vivo	vivo	ADJ
dpc-1620	174	30	confocal	confocal	ADJ
dpc-1620	174	31	microscopy	microscopy	NOUN
dpc-1620	174	32	.	.	PUNCT
dpc-1620	174	33	 	 	SPACE
dpc-1620	175	1	lasers	laser	NOUN
dpc-1620	175	2	med	med	PROPN
dpc-1620	175	3	sci	sci	PROPN
dpc-1620	175	4	.	.	PROPN
dpc-1620	175	5	2013;28:769	2013;28:769	NUM
dpc-1620	175	6	-	-	SYM
dpc-1620	175	7	776	776	NUM
dpc-1620	175	8	.	.	PUNCT
dpc-1620	176	1	doi:10.1007	doi:10.1007	VERB
dpc-1620	176	2	/	/	SYM
dpc-1620	176	3	s10103	s10103	NOUN
dpc-1620	176	4	-	-	NOUN
dpc-1620	176	5	012	012	NUM
dpc-1620	176	6	-	-	PUNCT
dpc-1620	176	7	1145	1145	NUM
dpc-1620	176	8	-	-	SYM
dpc-1620	176	9	9	9	NUM
dpc-1620	176	10	.	.	PUNCT
dpc-1620	177	1	pmid	pmid	NOUN
dpc-1620	177	2	:	:	PUNCT
dpc-1620	177	3	22767322	22767322	NUM
dpc-1620	177	4	.	.	X
dpc-1620	178	1	2	2	X
dpc-1620	178	2	.	.	X
dpc-1620	178	3	rovatti	rovatti	NOUN
dpc-1620	178	4	pp	pp	ADV
dpc-1620	178	5	,	,	PUNCT
dpc-1620	178	6	pellacani	pellacani	VERB
dpc-1620	178	7	g	g	PROPN
dpc-1620	178	8	,	,	PUNCT
dpc-1620	178	9	guida	guida	PROPN
dpc-1620	178	10	s.	s.	PROPN
dpc-1620	178	11	hyperdiluted	hyperdilute	VERB
dpc-1620	178	12	calcium	calcium	NOUN
dpc-1620	178	13	hydroxylapatite	hydroxylapatite	ADJ
dpc-1620	178	14	1	1	NUM
dpc-1620	178	15	:	:	SYM
dpc-1620	178	16	2	2	NUM
dpc-1620	178	17	for	for	ADP
dpc-1620	178	18	mid	mid	ADJ
dpc-1620	178	19	and	and	CCONJ
dpc-1620	178	20	lower	low	ADJ
dpc-1620	178	21	facial	facial	ADJ
dpc-1620	178	22	skin	skin	NOUN
dpc-1620	178	23	rejuvenation	rejuvenation	NOUN
dpc-1620	178	24	:	:	PUNCT
dpc-1620	178	25	efficacy	efficacy	NOUN
dpc-1620	178	26	and	and	CCONJ
dpc-1620	178	27	safety	safety	NOUN
dpc-1620	178	28	.	.	PUNCT
dpc-1620	179	1	dermatol	dermatol	NOUN
dpc-1620	179	2	surg	surg	NOUN
dpc-1620	179	3	.	.	PUNCT
dpc-1620	180	1	2020	2020	NUM
dpc-1620	180	2	;	;	PUNCT
dpc-1620	180	3	46	46	NUM
dpc-1620	180	4	:	:	PUNCT
dpc-1620	180	5	e112	e112	PROPN
dpc-1620	180	6	-	-	PUNCT
dpc-1620	180	7	e117	e117	PROPN
dpc-1620	180	8	.	.	PUNCT
dpc-1620	181	1	doi	doi	NOUN
dpc-1620	181	2	:	:	PUNCT
dpc-1620	181	3	10.1097/	10.1097/	NUM
dpc-1620	181	4	dss.0000000000002375	dss.0000000000002375	NOUN
dpc-1620	181	5	.	.	PUNCT
dpc-1620	182	1	pmid	pmid	NOUN
dpc-1620	182	2	:	:	PUNCT
dpc-1620	182	3	32205749	32205749	NUM
dpc-1620	182	4	.	.	PUNCT
dpc-1620	183	1	3	3	X
dpc-1620	183	2	.	.	X
dpc-1620	183	3	yaar	yaar	PROPN
dpc-1620	183	4	m	m	PROPN
dpc-1620	183	5	,	,	PUNCT
dpc-1620	183	6	gilchrest	gilchr	ADJ
dpc-1620	183	7	ba	ba	NOUN
dpc-1620	183	8	.	.	PUNCT
dpc-1620	184	1	photoageing	photoagee	VERB
dpc-1620	184	2	:	:	PUNCT
dpc-1620	184	3	mechanism	mechanism	NOUN
dpc-1620	184	4	,	,	PUNCT
dpc-1620	184	5	prevention	prevention	NOUN
dpc-1620	184	6	and	and	CCONJ
dpc-1620	184	7	therapy	therapy	NOUN
dpc-1620	184	8	.	.	PUNCT
dpc-1620	185	1	br	br	PROPN
dpc-1620	185	2	j	j	PROPN
dpc-1620	185	3	dermatol	dermatol	NOUN
dpc-1620	185	4	.	.	PUNCT
dpc-1620	186	1	2007	2007	NUM
dpc-1620	186	2	;	;	PUNCT
dpc-1620	186	3	157:874–87	157:874–87	NUM
dpc-1620	186	4	.	.	PUNCT
dpc-1620	187	1	doi:10.1111	doi:10.1111	PROPN
dpc-1620	187	2	/	/	SYM
dpc-1620	187	3	j.13652133.2007.08108.x	j.13652133.2007.08108.x	PROPN
dpc-1620	187	4	.	.	PUNCT
dpc-1620	188	1	pmid	pmid	NOUN
dpc-1620	188	2	:	:	PUNCT
dpc-1620	188	3	17711532	17711532	NUM
dpc-1620	188	4	.	.	PUNCT
dpc-1620	189	1	4	4	X
dpc-1620	189	2	.	.	X
dpc-1620	189	3	sachs	sachs	PROPN
dpc-1620	189	4	dl	dl	PROPN
dpc-1620	189	5	,	,	PUNCT
dpc-1620	189	6	varani	varani	PROPN
dpc-1620	189	7	j	j	PROPN
dpc-1620	189	8	,	,	PUNCT
dpc-1620	189	9	chubb	chubb	PROPN
dpc-1620	189	10	h	h	PROPN
dpc-1620	189	11	,	,	PUNCT
dpc-1620	189	12	et	et	PROPN
dpc-1620	189	13	al	al	PROPN
dpc-1620	189	14	.	.	PROPN
dpc-1620	190	1	atrophic	atrophic	ADJ
dpc-1620	190	2	and	and	CCONJ
dpc-1620	190	3	hypertrophic	hypertrophic	ADJ
dpc-1620	190	4	photoaging	photoaging	NOUN
dpc-1620	190	5	:	:	PUNCT
dpc-1620	190	6	clinical	clinical	ADJ
dpc-1620	190	7	,	,	PUNCT
dpc-1620	190	8	histologic	histologic	ADJ
dpc-1620	190	9	,	,	PUNCT
dpc-1620	190	10	and	and	CCONJ
dpc-1620	190	11	molecular	molecular	ADJ
dpc-1620	190	12	features	feature	NOUN
dpc-1620	190	13	of	of	ADP
dpc-1620	190	14	2	2	NUM
dpc-1620	190	15	distinct	distinct	ADJ
dpc-1620	190	16	phenotypes	phenotype	NOUN
dpc-1620	190	17	of	of	ADP
dpc-1620	190	18	photoaged	photoage	VERB
dpc-1620	190	19	skin	skin	NOUN
dpc-1620	190	20	.	.	PUNCT
dpc-1620	191	1	j	j	PROPN
dpc-1620	191	2	am	be	AUX
dpc-1620	191	3	acad	acad	ADJ
dpc-1620	191	4	dermatol	dermatol	NOUN
dpc-1620	191	5	.	.	PUNCT
dpc-1620	192	1	review	review	NOUN
dpc-1620	192	2	|	|	ADV
dpc-1620	192	3	dermatol	dermatol	ADJ
dpc-1620	192	4	pract	pract	NOUN
dpc-1620	192	5	concept	concept	NOUN
dpc-1620	192	6	.	.	PUNCT
dpc-1620	193	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	193	2	2021068	2021068	NUM
dpc-1620	193	3	7	7	NUM
dpc-1620	193	4	2019;81:480	2019;81:480	NUM
dpc-1620	193	5	-	-	SYM
dpc-1620	193	6	488	488	NUM
dpc-1620	193	7	.	.	PUNCT
dpc-1620	194	1	doi	doi	NOUN
dpc-1620	194	2	:	:	PUNCT
dpc-1620	194	3	10.1016	10.1016	NUM
dpc-1620	194	4	/	/	SYM
dpc-1620	194	5	j.jaad.2019.03.081	j.jaad.2019.03.081	PROPN
dpc-1620	194	6	.	.	PUNCT
dpc-1620	195	1	pmid	pmid	NOUN
dpc-1620	195	2	:	:	PUNCT
dpc-1620	195	3	30954583	30954583	NUM
dpc-1620	195	4	.	.	PUNCT
dpc-1620	196	1	5	5	X
dpc-1620	196	2	.	.	X
dpc-1620	196	3	kennedy	kennedy	PROPN
dpc-1620	196	4	c	c	PROPN
dpc-1620	196	5	,	,	PUNCT
dpc-1620	196	6	bajdik	bajdik	PROPN
dpc-1620	196	7	cd	cd	PROPN
dpc-1620	196	8	,	,	PUNCT
dpc-1620	196	9	willemze	willemze	ADJ
dpc-1620	196	10	r	r	NOUN
dpc-1620	196	11	,	,	PUNCT
dpc-1620	196	12	et	et	PROPN
dpc-1620	196	13	al	al	PROPN
dpc-1620	196	14	.	.	PUNCT
dpc-1620	197	1	the	the	DET
dpc-1620	197	2	influence	influence	NOUN
dpc-1620	197	3	of	of	ADP
dpc-1620	197	4	painful	painful	ADJ
dpc-1620	197	5	sunburns	sunburn	NOUN
dpc-1620	197	6	and	and	CCONJ
dpc-1620	197	7	lifetime	lifetime	NOUN
dpc-1620	197	8	sun	sun	NOUN
dpc-1620	197	9	exposure	exposure	NOUN
dpc-1620	197	10	on	on	ADP
dpc-1620	197	11	the	the	DET
dpc-1620	197	12	risk	risk	NOUN
dpc-1620	197	13	of	of	ADP
dpc-1620	197	14	actinic	actinic	ADJ
dpc-1620	197	15	keratoses	keratose	NOUN
dpc-1620	197	16	,	,	PUNCT
dpc-1620	197	17	seborrheic	seborrheic	ADJ
dpc-1620	197	18	warts	wart	NOUN
dpc-1620	197	19	,	,	PUNCT
dpc-1620	197	20	melanocytic	melanocytic	ADJ
dpc-1620	197	21	nevi	nevi	ADJ
dpc-1620	197	22	,	,	PUNCT
dpc-1620	197	23	atypical	atypical	ADJ
dpc-1620	197	24	nevi	nevi	NOUN
dpc-1620	197	25	,	,	PUNCT
dpc-1620	197	26	and	and	CCONJ
dpc-1620	197	27	skin	skin	NOUN
dpc-1620	197	28	cancer	cancer	NOUN
dpc-1620	197	29	.	.	PUNCT
dpc-1620	198	1	j	j	PROPN
dpc-1620	198	2	invest	invest	VERB
dpc-1620	198	3	dermatol	dermatol	NOUN
dpc-1620	198	4	.	.	PUNCT
dpc-1620	199	1	2003;120:1087	2003;120:1087	NUM
dpc-1620	199	2	-	-	SYM
dpc-1620	199	3	1093	1093	NUM
dpc-1620	199	4	.	.	PUNCT
dpc-1620	200	1	doi	doi	NOUN
dpc-1620	200	2	:	:	PUNCT
dpc-1620	200	3	10.1046	10.1046	NUM
dpc-1620	200	4	/	/	SYM
dpc-1620	200	5	j.1523	j.1523	NOUN
dpc-1620	200	6	-	-	PUNCT
dpc-1620	200	7	1747.2003.12246.x	1747.2003.12246.x	NUM
dpc-1620	200	8	.	.	PUNCT
dpc-1620	201	1	pmid	pmid	NOUN
dpc-1620	201	2	:	:	PUNCT
dpc-1620	201	3	12787139	12787139	NUM
dpc-1620	201	4	.	.	PUNCT
dpc-1620	202	1	6	6	X
dpc-1620	202	2	.	.	X
dpc-1620	202	3	meeran	meeran	VERB
dpc-1620	202	4	sm	sm	PROPN
dpc-1620	202	5	,	,	PUNCT
dpc-1620	202	6	punathil	punathil	PROPN
dpc-1620	202	7	t	t	PROPN
dpc-1620	202	8	,	,	PUNCT
dpc-1620	202	9	katiyar	katiyar	PROPN
dpc-1620	202	10	sk	sk	PROPN
dpc-1620	202	11	.	.	PROPN
dpc-1620	202	12	il-12	il-12	NOUN
dpc-1620	202	13	deficiency	deficiency	NOUN
dpc-1620	202	14	exacerbates	exacerbate	VERB
dpc-1620	202	15	inflammatory	inflammatory	ADJ
dpc-1620	202	16	responses	response	NOUN
dpc-1620	202	17	in	in	ADP
dpc-1620	202	18	uv	uv	NOUN
dpc-1620	202	19	-	-	PUNCT
dpc-1620	202	20	irradiated	irradiate	VERB
dpc-1620	202	21	skin	skin	NOUN
dpc-1620	202	22	and	and	CCONJ
dpc-1620	202	23	skin	skin	NOUN
dpc-1620	202	24	tumors	tumor	NOUN
dpc-1620	202	25	.	.	PUNCT
dpc-1620	203	1	j	j	PROPN
dpc-1620	203	2	invest	invest	VERB
dpc-1620	203	3	dermatol	dermatol	NOUN
dpc-1620	203	4	.	.	PUNCT
dpc-1620	204	1	2008;128:2716	2008;128:2716	NUM
dpc-1620	204	2	-	-	SYM
dpc-1620	204	3	2727	2727	NUM
dpc-1620	204	4	.	.	PUNCT
dpc-1620	205	1	doi	doi	NOUN
dpc-1620	205	2	:	:	PUNCT
dpc-1620	205	3	10.1038/	10.1038/	NUM
dpc-1620	205	4	jid.2008.140	jid.2008.140	PROPN
dpc-1620	205	5	.	.	PUNCT
dpc-1620	206	1	pmid	pmid	NOUN
dpc-1620	206	2	:	:	PUNCT
dpc-1620	206	3	18509359	18509359	NUM
dpc-1620	206	4	.	.	PUNCT
dpc-1620	207	1	7	7	X
dpc-1620	207	2	.	.	X
dpc-1620	207	3	gandini	gandini	PROPN
dpc-1620	207	4	s	s	PROPN
dpc-1620	207	5	,	,	PUNCT
dpc-1620	207	6	autier	autier	NOUN
dpc-1620	207	7	p	p	NOUN
dpc-1620	207	8	,	,	PUNCT
dpc-1620	207	9	boniol	boniol	ADJ
dpc-1620	207	10	m.	m.	NOUN
dpc-1620	207	11	reviews	review	NOUN
dpc-1620	207	12	on	on	ADP
dpc-1620	207	13	sun	sun	PROPN
dpc-1620	207	14	exposure	exposure	NOUN
dpc-1620	207	15	and	and	CCONJ
dpc-1620	207	16	artificial	artificial	ADJ
dpc-1620	207	17	light	light	NOUN
dpc-1620	207	18	and	and	CCONJ
dpc-1620	207	19	melanoma	melanoma	NOUN
dpc-1620	207	20	.	.	PUNCT
dpc-1620	208	1	prog	prog	PROPN
dpc-1620	208	2	biophys	biophy	NOUN
dpc-1620	208	3	mol	mol	ADP
dpc-1620	208	4	biol	biol	PROPN
dpc-1620	208	5	.	.	PUNCT
dpc-1620	209	1	2011;107:362366	2011;107:362366	NUM
dpc-1620	209	2	.	.	PUNCT
dpc-1620	210	1	doi	doi	NOUN
dpc-1620	210	2	:	:	PUNCT
dpc-1620	210	3	10.1016	10.1016	NUM
dpc-1620	210	4	/	/	SYM
dpc-1620	210	5	j.pbiomolbio.2011.09.011.pmid	j.pbiomolbio.2011.09.011.pmid	NOUN
dpc-1620	210	6	:	:	PUNCT
dpc-1620	210	7	21958910	21958910	NUM
dpc-1620	210	8	.	.	PUNCT
dpc-1620	211	1	8	8	X
dpc-1620	211	2	.	.	PUNCT
dpc-1620	211	3	franceschi	franceschi	PROPN
dpc-1620	211	4	s	s	PROPN
dpc-1620	211	5	,	,	PUNCT
dpc-1620	211	6	levi	levi	PROPN
dpc-1620	211	7	f	f	PROPN
dpc-1620	211	8	,	,	PUNCT
dpc-1620	211	9	randimbison	randimbison	NOUN
dpc-1620	211	10	l	l	NOUN
dpc-1620	211	11	,	,	PUNCT
dpc-1620	211	12	la	la	PROPN
dpc-1620	211	13	vecchia	vecchia	PROPN
dpc-1620	211	14	c.	c.	PROPN
dpc-1620	211	15	site	site	NOUN
dpc-1620	211	16	distribution	distribution	NOUN
dpc-1620	211	17	of	of	ADP
dpc-1620	211	18	different	different	ADJ
dpc-1620	211	19	types	type	NOUN
dpc-1620	211	20	of	of	ADP
dpc-1620	211	21	skin	skin	NOUN
dpc-1620	211	22	cancer	cancer	NOUN
dpc-1620	211	23	:	:	PUNCT
dpc-1620	211	24	new	new	ADJ
dpc-1620	211	25	aetiological	aetiological	ADJ
dpc-1620	211	26	clues	clue	NOUN
dpc-1620	211	27	.	.	PUNCT
dpc-1620	212	1	int	int	NOUN
dpc-1620	212	2	j	j	PROPN
dpc-1620	212	3	cancer	cancer	NOUN
dpc-1620	212	4	.	.	PUNCT
dpc-1620	213	1	1996;67:24	1996;67:24	NUM
dpc-1620	213	2	-	-	PUNCT
dpc-1620	213	3	28	28	NUM
dpc-1620	213	4	.	.	PUNCT
dpc-1620	214	1	doi	doi	NOUN
dpc-1620	214	2	:	:	PUNCT
dpc-1620	214	3	10.1002/(sici)10970215(19960703)67:1<24::aid	10.1002/(sici)10970215(19960703)67:1<24::aid	NUM
dpc-1620	214	4	-	-	PUNCT
dpc-1620	214	5	ijc6>3.0.co;2	ijc6>3.0.co;2	NOUN
dpc-1620	214	6	-	-	PUNCT
dpc-1620	214	7	1	1	NUM
dpc-1620	214	8	.	.	PUNCT
dpc-1620	215	1	pmid	pmid	NOUN
dpc-1620	215	2	:	:	PUNCT
dpc-1620	215	3	8690520	8690520	NUM
dpc-1620	215	4	.	.	PUNCT
dpc-1620	216	1	9	9	X
dpc-1620	216	2	.	.	X
dpc-1620	216	3	pellacani	pellacani	PROPN
dpc-1620	216	4	g	g	PROPN
dpc-1620	216	5	,	,	PUNCT
dpc-1620	216	6	scope	scope	NOUN
dpc-1620	216	7	a	a	PRON
dpc-1620	216	8	,	,	PUNCT
dpc-1620	216	9	gonzalez	gonzalez	PROPN
dpc-1620	216	10	s	s	PROPN
dpc-1620	216	11	,	,	PUNCT
dpc-1620	216	12	et	et	PROPN
dpc-1620	216	13	al	al	PROPN
dpc-1620	216	14	.	.	PROPN
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dpc-1620	217	2	confocal	confocal	ADJ
dpc-1620	217	3	microscopy	microscopy	NOUN
dpc-1620	217	4	made	make	VERB
dpc-1620	217	5	easy	easy	ADJ
dpc-1620	217	6	:	:	PUNCT
dpc-1620	217	7	the	the	DET
dpc-1620	217	8	4	4	NUM
dpc-1620	217	9	must	must	AUX
dpc-1620	217	10	-	-	PUNCT
dpc-1620	217	11	know	know	VERB
dpc-1620	217	12	key	key	ADJ
dpc-1620	217	13	features	feature	NOUN
dpc-1620	217	14	for	for	ADP
dpc-1620	217	15	the	the	DET
dpc-1620	217	16	diagnosis	diagnosis	NOUN
dpc-1620	217	17	of	of	ADP
dpc-1620	217	18	melanoma	melanoma	NOUN
dpc-1620	217	19	and	and	CCONJ
dpc-1620	217	20	nonmelanoma	nonmelanoma	ADJ
dpc-1620	217	21	skin	skin	NOUN
dpc-1620	217	22	cancers	cancer	NOUN
dpc-1620	217	23	.	.	PUNCT
dpc-1620	218	1	j	j	PROPN
dpc-1620	218	2	am	be	AUX
dpc-1620	218	3	acad	acad	ADJ
dpc-1620	218	4	dermatol	dermatol	NOUN
dpc-1620	218	5	.	.	PUNCT
dpc-1620	219	1	2019;81:520	2019;81:520	VERB
dpc-1620	219	2	-	-	SYM
dpc-1620	219	3	526	526	NUM
dpc-1620	219	4	.	.	PUNCT
dpc-1620	220	1	doi	doi	NOUN
dpc-1620	220	2	:	:	PUNCT
dpc-1620	220	3	10.1016	10.1016	NUM
dpc-1620	220	4	/	/	SYM
dpc-1620	220	5	j.jaad.2019.03.085	j.jaad.2019.03.085	PROPN
dpc-1620	220	6	.	.	PUNCT
dpc-1620	221	1	pmid	pmid	NOUN
dpc-1620	221	2	:	:	PUNCT
dpc-1620	221	3	30954581	30954581	NUM
dpc-1620	221	4	.	.	PUNCT
dpc-1620	222	1	10	10	NUM
dpc-1620	222	2	.	.	X
dpc-1620	223	1	pezzini	pezzini	PROPN
dpc-1620	223	2	c	c	PROPN
dpc-1620	223	3	,	,	PUNCT
dpc-1620	223	4	kaleci	kaleci	PROPN
dpc-1620	223	5	s	s	PROPN
dpc-1620	223	6	,	,	PUNCT
dpc-1620	223	7	chester	chester	PROPN
dpc-1620	223	8	j	j	PROPN
dpc-1620	223	9	,	,	PUNCT
dpc-1620	223	10	farnetani	farnetani	PROPN
dpc-1620	223	11	f	f	X
dpc-1620	223	12	,	,	PUNCT
dpc-1620	223	13	longo	longo	PROPN
dpc-1620	223	14	c	c	PROPN
dpc-1620	223	15	,	,	PUNCT
dpc-1620	223	16	pellacani	pellacani	ADJ
dpc-1620	223	17	g.	g.	PROPN
dpc-1620	223	18	reflectance	reflectance	NOUN
dpc-1620	223	19	confocal	confocal	ADJ
dpc-1620	223	20	microscopy	microscopy	NOUN
dpc-1620	223	21	diagnostic	diagnostic	ADJ
dpc-1620	223	22	accuracy	accuracy	NOUN
dpc-1620	223	23	for	for	ADP
dpc-1620	223	24	malignant	malignant	ADJ
dpc-1620	223	25	melanoma	melanoma	NOUN
dpc-1620	223	26	in	in	ADP
dpc-1620	223	27	different	different	ADJ
dpc-1620	223	28	clinical	clinical	ADJ
dpc-1620	223	29	settings	setting	NOUN
dpc-1620	223	30	:	:	PUNCT
dpc-1620	223	31	systematic	systematic	ADJ
dpc-1620	223	32	review	review	NOUN
dpc-1620	223	33	and	and	CCONJ
dpc-1620	223	34	meta	meta	ADJ
dpc-1620	223	35	-	-	PUNCT
dpc-1620	223	36	analysis	analysis	NOUN
dpc-1620	223	37	.	.	PUNCT
dpc-1620	224	1	j	j	PROPN
dpc-1620	224	2	eur	eur	PROPN
dpc-1620	224	3	acad	acad	PROPN
dpc-1620	224	4	dermatol	dermatol	NOUN
dpc-1620	224	5	venereol	venereol	NOUN
dpc-1620	224	6	.	.	PUNCT
dpc-1620	225	1	2020;34:22682279	2020;34:22682279	NUM
dpc-1620	225	2	.	.	PUNCT
dpc-1620	225	3	doi	doi	NOUN
dpc-1620	225	4	:	:	PUNCT
dpc-1620	225	5	10.1111	10.1111	NUM
dpc-1620	225	6	/	/	SYM
dpc-1620	225	7	jdv.16248	jdv.16248	PROPN
dpc-1620	225	8	.	.	PUNCT
dpc-1620	226	1	pmid	pmid	NOUN
dpc-1620	226	2	:	:	PUNCT
dpc-1620	226	3	31997465	31997465	NUM
dpc-1620	226	4	.	.	PUNCT
dpc-1620	227	1	11	11	NUM
dpc-1620	227	2	.	.	PUNCT
dpc-1620	228	1	guida	guida	PROPN
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dpc-1620	228	3	,	,	PUNCT
dpc-1620	228	4	de	de	X
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dpc-1620	228	6	b	b	NOUN
dpc-1620	228	7	,	,	PUNCT
dpc-1620	228	8	ciardo	ciardo	NOUN
dpc-1620	228	9	s	s	PROPN
dpc-1620	228	10	,	,	PUNCT
dpc-1620	228	11	farnetani	farnetani	X
dpc-1620	228	12	f	f	X
dpc-1620	228	13	,	,	PUNCT
dpc-1620	228	14	pellacani	pellacani	PROPN
dpc-1620	228	15	g.	g.	PROPN
dpc-1620	228	16	non	non	ADJ
dpc-1620	228	17	-	-	ADJ
dpc-1620	228	18	invasive	invasive	ADJ
dpc-1620	228	19	imaging	imaging	NOUN
dpc-1620	228	20	for	for	ADP
dpc-1620	228	21	skin	skin	NOUN
dpc-1620	228	22	cancers	cancer	NOUN
dpc-1620	228	23	—	—	PUNCT
dpc-1620	228	24	the	the	DET
dpc-1620	228	25	european	european	ADJ
dpc-1620	228	26	experience	experience	NOUN
dpc-1620	228	27	.	.	PUNCT
dpc-1620	229	1	curr	curr	PROPN
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dpc-1620	229	5	;	;	PUNCT
dpc-1620	229	6	8:172	8:172	NUM
dpc-1620	229	7	-	-	SYM
dpc-1620	229	8	181	181	NUM
dpc-1620	229	9	.	.	PUNCT
dpc-1620	230	1	doi	doi	NOUN
dpc-1620	230	2	:	:	PUNCT
dpc-1620	230	3	10.1007	10.1007	NUM
dpc-1620	230	4	/	/	SYM
dpc-1620	230	5	s13671	s13671	NOUN
dpc-1620	230	6	-	-	PUNCT
dpc-1620	230	7	019	019	NUM
dpc-1620	230	8	-	-	PUNCT
dpc-1620	230	9	00269	00269	NUM
dpc-1620	230	10	-	-	PUNCT
dpc-1620	230	11	y.	y.	NOUN
dpc-1620	230	12	12	12	NUM
dpc-1620	230	13	.	.	PUNCT
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dpc-1620	231	3	,	,	PUNCT
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dpc-1620	231	5	c	c	PROPN
dpc-1620	231	6	,	,	PUNCT
dpc-1620	231	7	di	di	X
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dpc-1620	231	9	n	n	CCONJ
dpc-1620	231	10	,	,	PUNCT
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dpc-1620	231	16	,	,	PUNCT
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dpc-1620	231	20	of	of	ADP
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dpc-1620	231	22	imaging	imaging	NOUN
dpc-1620	231	23	in	in	ADP
dpc-1620	231	24	the	the	DET
dpc-1620	231	25	management	management	NOUN
dpc-1620	231	26	of	of	ADP
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dpc-1620	231	28	cancer	cancer	NOUN
dpc-1620	231	29	.	.	PUNCT
dpc-1620	232	1	curr	curr	PROPN
dpc-1620	232	2	opin	opin	PROPN
dpc-1620	232	3	oncol	oncol	PROPN
dpc-1620	232	4	.	.	PUNCT
dpc-1620	233	1	2020;32:98	2020;32:98	NUM
dpc-1620	233	2	-	-	SYM
dpc-1620	233	3	105	105	NUM
dpc-1620	233	4	.	.	PUNCT
dpc-1620	233	5	doi	doi	NOUN
dpc-1620	233	6	:	:	PUNCT
dpc-1620	233	7	10.1097/	10.1097/	NUM
dpc-1620	233	8	cco.0000000000000611	cco.0000000000000611	NOUN
dpc-1620	233	9	.	.	PUNCT
dpc-1620	234	1	pmid	pmid	NOUN
dpc-1620	234	2	:	:	PUNCT
dpc-1620	234	3	31850969	31850969	NUM
dpc-1620	234	4	.	.	PUNCT
dpc-1620	235	1	13	13	NUM
dpc-1620	235	2	.	.	X
dpc-1620	236	1	longo	longo	PROPN
dpc-1620	236	2	c	c	PROPN
dpc-1620	236	3	,	,	PUNCT
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dpc-1620	236	5	a	a	X
dpc-1620	236	6	,	,	PUNCT
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dpc-1620	236	14	g.	g.	PROPN
dpc-1620	236	15	skin	skin	NOUN
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dpc-1620	236	17	:	:	PUNCT
dpc-1620	236	18	in	in	ADP
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dpc-1620	236	20	microscopic	microscopic	ADJ
dpc-1620	236	21	assessment	assessment	NOUN
dpc-1620	236	22	of	of	ADP
dpc-1620	236	23	epidermal	epidermal	ADJ
dpc-1620	236	24	and	and	CCONJ
dpc-1620	236	25	dermal	dermal	ADJ
dpc-1620	236	26	changes	change	NOUN
dpc-1620	236	27	by	by	ADP
dpc-1620	236	28	means	mean	NOUN
dpc-1620	236	29	of	of	ADP
dpc-1620	236	30	confocal	confocal	ADJ
dpc-1620	236	31	microscopy	microscopy	NOUN
dpc-1620	236	32	.	.	PUNCT
dpc-1620	237	1	j	j	PROPN
dpc-1620	237	2	am	be	AUX
dpc-1620	237	3	acad	acad	ADJ
dpc-1620	237	4	dermatol	dermatol	NOUN
dpc-1620	237	5	.	.	PUNCT
dpc-1620	238	1	2013;68	2013;68	NUM
dpc-1620	238	2	:	:	PUNCT
dpc-1620	238	3	e7382	e7382	VERB
dpc-1620	238	4	.	.	PUNCT
dpc-1620	239	1	doi	doi	PROPN
dpc-1620	239	2	:	:	PUNCT
dpc-1620	239	3	10.1016	10.1016	NUM
dpc-1620	239	4	/	/	SYM
dpc-1620	239	5	j.jaad.2011.08.021	j.jaad.2011.08.021	PROPN
dpc-1620	239	6	.	.	PUNCT
dpc-1620	240	1	pmid	pmid	NOUN
dpc-1620	240	2	:	:	PUNCT
dpc-1620	240	3	22000768	22000768	NUM
dpc-1620	240	4	.	.	PUNCT
dpc-1620	241	1	14	14	NUM
dpc-1620	241	2	.	.	PUNCT
dpc-1620	242	1	rajadhyaksha	rajadhyaksha	PROPN
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dpc-1620	242	3	,	,	PUNCT
dpc-1620	242	4	grossman	grossman	PROPN
dpc-1620	242	5	m	m	PROPN
dpc-1620	242	6	,	,	PUNCT
dpc-1620	242	7	esterowitz	esterowitz	PROPN
dpc-1620	242	8	d	d	PROPN
dpc-1620	242	9	,	,	PUNCT
dpc-1620	242	10	webb	webb	PROPN
dpc-1620	242	11	rh	rh	PROPN
dpc-1620	242	12	,	,	PUNCT
dpc-1620	242	13	anderson	anderson	PROPN
dpc-1620	242	14	rr	rr	PROPN
dpc-1620	242	15	.	.	PUNCT
dpc-1620	243	1	in	in	ADP
dpc-1620	243	2	vivo	vivo	ADJ
dpc-1620	243	3	confocal	confocal	ADJ
dpc-1620	243	4	scanning	scanning	NOUN
dpc-1620	243	5	laser	laser	NOUN
dpc-1620	243	6	microscopy	microscopy	NOUN
dpc-1620	243	7	of	of	ADP
dpc-1620	243	8	human	human	ADJ
dpc-1620	243	9	skin	skin	NOUN
dpc-1620	243	10	:	:	PUNCT
dpc-1620	243	11	melanin	melanin	NOUN
dpc-1620	243	12	provides	provide	VERB
dpc-1620	243	13	strong	strong	ADJ
dpc-1620	243	14	contrast	contrast	NOUN
dpc-1620	243	15	.	.	PUNCT
dpc-1620	244	1	j	j	PROPN
dpc-1620	244	2	invest	invest	VERB
dpc-1620	244	3	dermatol	dermatol	NOUN
dpc-1620	244	4	.	.	PUNCT
dpc-1620	245	1	1995;104:946	1995;104:946	NUM
dpc-1620	245	2	-	-	SYM
dpc-1620	245	3	52	52	NUM
dpc-1620	245	4	.	.	PUNCT
dpc-1620	246	1	doi	doi	NOUN
dpc-1620	246	2	:	:	PUNCT
dpc-1620	246	3	10.1111/1523	10.1111/1523	NUM
dpc-1620	246	4	-	-	NUM
dpc-1620	246	5	1747.ep12606215	1747.ep12606215	NOUN
dpc-1620	246	6	.	.	PUNCT
dpc-1620	247	1	pmid	pmid	NOUN
dpc-1620	247	2	:	:	PUNCT
dpc-1620	247	3	7769264	7769264	NUM
dpc-1620	247	4	.	.	PUNCT
dpc-1620	248	1	15	15	NUM
dpc-1620	248	2	.	.	PUNCT
dpc-1620	249	1	sauermann	sauermann	PROPN
dpc-1620	249	2	k	k	PROPN
dpc-1620	249	3	,	,	PUNCT
dpc-1620	249	4	clemann	clemann	PROPN
dpc-1620	249	5	s	s	PROPN
dpc-1620	249	6	,	,	PUNCT
dpc-1620	249	7	jaspers	jaspers	PROPN
dpc-1620	249	8	s	s	PART
dpc-1620	249	9	,	,	PUNCT
dpc-1620	249	10	et	et	PROPN
dpc-1620	249	11	al	al	PROPN
dpc-1620	249	12	.	.	PUNCT
dpc-1620	249	13	age	age	NOUN
dpc-1620	249	14	related	relate	VERB
dpc-1620	249	15	changes	change	NOUN
dpc-1620	249	16	of	of	ADP
dpc-1620	249	17	human	human	ADJ
dpc-1620	249	18	skin	skin	NOUN
dpc-1620	249	19	investigated	investigate	VERB
dpc-1620	249	20	with	with	ADP
dpc-1620	249	21	histometric	histometric	ADJ
dpc-1620	249	22	measurements	measurement	NOUN
dpc-1620	249	23	by	by	ADP
dpc-1620	249	24	confocal	confocal	ADJ
dpc-1620	249	25	laser	laser	NOUN
dpc-1620	249	26	scanning	scan	VERB
dpc-1620	249	27	microscopy	microscopy	NOUN
dpc-1620	249	28	in	in	ADP
dpc-1620	249	29	vivo	vivo	NOUN
dpc-1620	249	30	.	.	PUNCT
dpc-1620	250	1	skin	skin	NOUN
dpc-1620	250	2	res	re	NOUN
dpc-1620	250	3	technol	technol	NOUN
dpc-1620	250	4	.	.	PUNCT
dpc-1620	250	5	2002;8:5256	2002;8:5256	NUM
dpc-1620	250	6	.	.	PUNCT
dpc-1620	251	1	doi	doi	NOUN
dpc-1620	251	2	:	:	PUNCT
dpc-1620	251	3	10.1046	10.1046	NUM
dpc-1620	251	4	/	/	SYM
dpc-1620	251	5	j.0909	j.0909	NOUN
dpc-1620	251	6	-	-	PUNCT
dpc-1620	251	7	752x.2001.10297.x	752x.2001.10297.x	NOUN
dpc-1620	251	8	.	.	PUNCT
dpc-1620	252	1	pmid	pmid	NOUN
dpc-1620	252	2	:	:	PUNCT
dpc-1620	252	3	12005120	12005120	NUM
dpc-1620	252	4	.	.	PUNCT
dpc-1620	253	1	16	16	NUM
dpc-1620	253	2	.	.	PUNCT
dpc-1620	254	1	longo	longo	PROPN
dpc-1620	254	2	c.	c.	PROPN
dpc-1620	254	3	well	well	ADV
dpc-1620	254	4	-	-	PUNCT
dpc-1620	254	5	aging	aging	NOUN
dpc-1620	254	6	:	:	PUNCT
dpc-1620	254	7	early	early	ADJ
dpc-1620	254	8	detection	detection	NOUN
dpc-1620	254	9	of	of	ADP
dpc-1620	254	10	skin	skin	NOUN
dpc-1620	254	11	aging	age	VERB
dpc-1620	254	12	signs	sign	NOUN
dpc-1620	254	13	.	.	PUNCT
dpc-1620	255	1	dermatol	dermatol	NOUN
dpc-1620	255	2	clin	clin	PROPN
dpc-1620	255	3	.	.	PUNCT
dpc-1620	256	1	2016	2016	NUM
dpc-1620	256	2	;	;	PUNCT
dpc-1620	256	3	34:513	34:513	NUM
dpc-1620	256	4	-	-	SYM
dpc-1620	256	5	518	518	NUM
dpc-1620	256	6	.	.	PUNCT
dpc-1620	257	1	doi	doi	NOUN
dpc-1620	257	2	:	:	PUNCT
dpc-1620	257	3	10.1016	10.1016	NUM
dpc-1620	257	4	/	/	SYM
dpc-1620	257	5	j.det.2016.05.014	j.det.2016.05.014	PROPN
dpc-1620	257	6	.	.	PUNCT
dpc-1620	258	1	pmid	pmid	NOUN
dpc-1620	258	2	:	:	PUNCT
dpc-1620	258	3	27692457	27692457	NUM
dpc-1620	258	4	.	.	PUNCT
dpc-1620	259	1	17	17	NUM
dpc-1620	259	2	.	.	PUNCT
dpc-1620	260	1	longo	longo	PROPN
dpc-1620	260	2	c	c	PROPN
dpc-1620	260	3	,	,	PUNCT
dpc-1620	260	4	casari	casari	PROPN
dpc-1620	260	5	a	a	X
dpc-1620	260	6	,	,	PUNCT
dpc-1620	260	7	de	de	X
dpc-1620	260	8	pace	pace	NOUN
dpc-1620	260	9	b	b	NOUN
dpc-1620	260	10	,	,	PUNCT
dpc-1620	260	11	et	et	PROPN
dpc-1620	260	12	al	al	PROPN
dpc-1620	260	13	.	.	PROPN
dpc-1620	260	14	proposal	proposal	NOUN
dpc-1620	260	15	for	for	ADP
dpc-1620	260	16	an	an	DET
dpc-1620	260	17	in	in	ADP
dpc-1620	260	18	vivo	vivo	ADJ
dpc-1620	260	19	histopathologic	histopathologic	ADJ
dpc-1620	260	20	scoring	scoring	NOUN
dpc-1620	260	21	system	system	NOUN
dpc-1620	260	22	for	for	ADP
dpc-1620	260	23	skin	skin	NOUN
dpc-1620	260	24	aging	age	VERB
dpc-1620	260	25	by	by	ADP
dpc-1620	260	26	means	mean	NOUN
dpc-1620	260	27	of	of	ADP
dpc-1620	260	28	confocal	confocal	ADJ
dpc-1620	260	29	microscopy	microscopy	NOUN
dpc-1620	260	30	.	.	PUNCT
dpc-1620	261	1	skin	skin	NOUN
dpc-1620	261	2	res	re	NOUN
dpc-1620	261	3	technol	technol	NOUN
dpc-1620	261	4	.	.	PUNCT
dpc-1620	262	1	2013;19	2013;19	NUM
dpc-1620	262	2	:	:	PUNCT
dpc-1620	262	3	e167	e167	PROPN
dpc-1620	262	4	-	-	SYM
dpc-1620	262	5	73	73	NUM
dpc-1620	262	6	.	.	PUNCT
dpc-1620	263	1	doi	doi	NOUN
dpc-1620	263	2	:	:	PUNCT
dpc-1620	263	3	10.1111	10.1111	NUM
dpc-1620	263	4	/	/	SYM
dpc-1620	263	5	j.1600	j.1600	NOUN
dpc-1620	263	6	-	-	PUNCT
dpc-1620	263	7	0846.2012.00623.x	0846.2012.00623.x	NOUN
dpc-1620	263	8	.	.	PUNCT
dpc-1620	264	1	pmid	pmid	NOUN
dpc-1620	264	2	:	:	PUNCT
dpc-1620	264	3	22672873	22672873	NUM
dpc-1620	264	4	.	.	PUNCT
dpc-1620	265	1	18	18	NUM
dpc-1620	265	2	.	.	X
dpc-1620	266	1	longo	longo	PROPN
dpc-1620	266	2	c	c	PROPN
dpc-1620	266	3	,	,	PUNCT
dpc-1620	266	4	zalaudek	zalaudek	PROPN
dpc-1620	266	5	i	i	PRON
dpc-1620	266	6	,	,	PUNCT
dpc-1620	266	7	argenziano	argenziano	ADJ
dpc-1620	266	8	g	g	NOUN
dpc-1620	266	9	,	,	PUNCT
dpc-1620	266	10	pellacani	pellacani	PROPN
dpc-1620	266	11	g.	g.	PROPN
dpc-1620	266	12	new	new	ADJ
dpc-1620	266	13	directions	direction	NOUN
dpc-1620	266	14	in	in	ADP
dpc-1620	266	15	dermatopathology	dermatopathology	NOUN
dpc-1620	266	16	:	:	PUNCT
dpc-1620	266	17	in	in	ADP
dpc-1620	266	18	vivo	vivo	ADJ
dpc-1620	266	19	confocal	confocal	ADJ
dpc-1620	266	20	microscopy	microscopy	NOUN
dpc-1620	266	21	in	in	ADP
dpc-1620	266	22	clinical	clinical	ADJ
dpc-1620	266	23	practice	practice	NOUN
dpc-1620	266	24	.	.	PUNCT
dpc-1620	267	1	dermatol	dermatol	NOUN
dpc-1620	267	2	clin	clin	PROPN
dpc-1620	267	3	.	.	PUNCT
dpc-1620	268	1	2012;30:799	2012;30:799	VERB
dpc-1620	268	2	-	-	PUNCT
dpc-1620	268	3	814	814	NUM
dpc-1620	268	4	.	.	PUNCT
dpc-1620	269	1	doi	doi	NOUN
dpc-1620	269	2	:	:	PUNCT
dpc-1620	269	3	10.1016	10.1016	NUM
dpc-1620	269	4	/	/	SYM
dpc-1620	269	5	j.	j.	PROPN
dpc-1620	269	6	det.2012.06.012	det.2012.06.012	PROPN
dpc-1620	269	7	.	.	PUNCT
dpc-1620	270	1	pmid	pmid	NOUN
dpc-1620	270	2	:	:	PUNCT
dpc-1620	270	3	23021059	23021059	NUM
dpc-1620	270	4	.	.	PUNCT
dpc-1620	271	1	19	19	NUM
dpc-1620	271	2	.	.	PUNCT
dpc-1620	271	3	cinotti	cinotti	PROPN
dpc-1620	271	4	e	e	NOUN
dpc-1620	271	5	,	,	PUNCT
dpc-1620	271	6	bovi	bovi	PROPN
dpc-1620	271	7	c	c	NOUN
dpc-1620	271	8	,	,	PUNCT
dpc-1620	271	9	tonini	tonini	PROPN
dpc-1620	271	10	g	g	PROPN
dpc-1620	271	11	,	,	PUNCT
dpc-1620	271	12	et	et	PROPN
dpc-1620	271	13	al	al	PROPN
dpc-1620	271	14	.	.	PROPN
dpc-1620	272	1	structural	structural	ADJ
dpc-1620	272	2	skin	skin	NOUN
dpc-1620	272	3	changes	change	NOUN
dpc-1620	272	4	in	in	ADP
dpc-1620	272	5	elderly	elderly	ADJ
dpc-1620	272	6	people	people	NOUN
dpc-1620	272	7	investigated	investigate	VERB
dpc-1620	272	8	by	by	ADP
dpc-1620	272	9	reflectance	reflectance	NOUN
dpc-1620	272	10	confocal	confocal	ADJ
dpc-1620	272	11	microscopy	microscopy	NOUN
dpc-1620	272	12	.	.	PUNCT
dpc-1620	273	1	j	j	PROPN
dpc-1620	273	2	eur	eur	PROPN
dpc-1620	273	3	acad	acad	PROPN
dpc-1620	273	4	dermatol	dermatol	NOUN
dpc-1620	273	5	venereol	venereol	NOUN
dpc-1620	273	6	.	.	PUNCT
dpc-1620	274	1	2020	2020	NUM
dpc-1620	274	2	;	;	PUNCT
dpc-1620	274	3	34(11):2652	34(11):2652	NUM
dpc-1620	274	4	-	-	SYM
dpc-1620	274	5	2658	2658	NUM
dpc-1620	274	6	.	.	PUNCT
dpc-1620	275	1	doi	doi	NOUN
dpc-1620	275	2	:	:	PUNCT
dpc-1620	275	3	10.1111	10.1111	NUM
dpc-1620	275	4	/	/	SYM
dpc-1620	275	5	jdv.16466	jdv.16466	NUM
dpc-1620	275	6	pmid	pmid	PROPN
dpc-1620	275	7	:	:	PUNCT
dpc-1620	275	8	32294278	32294278	NUM
dpc-1620	275	9	.	.	PUNCT
dpc-1620	276	1	20	20	NUM
dpc-1620	276	2	.	.	PUNCT
dpc-1620	276	3	wurm	wurm	PROPN
dpc-1620	276	4	em	em	PRON
dpc-1620	276	5	,	,	PUNCT
dpc-1620	276	6	longo	longo	PROPN
dpc-1620	276	7	c	c	PROPN
dpc-1620	276	8	,	,	PUNCT
dpc-1620	276	9	curchin	curchin	NOUN
dpc-1620	276	10	c	c	PROPN
dpc-1620	276	11	,	,	PUNCT
dpc-1620	276	12	et	et	PROPN
dpc-1620	276	13	al	al	PROPN
dpc-1620	276	14	.	.	PROPN
dpc-1620	277	1	in	in	ADP
dpc-1620	277	2	vivo	vivo	ADJ
dpc-1620	277	3	assessment	assessment	NOUN
dpc-1620	277	4	of	of	ADP
dpc-1620	277	5	chronological	chronological	ADJ
dpc-1620	277	6	ageing	ageing	NOUN
dpc-1620	277	7	and	and	CCONJ
dpc-1620	277	8	photoageing	photoagee	VERB
dpc-1620	277	9	in	in	ADP
dpc-1620	277	10	forearm	forearm	NOUN
dpc-1620	277	11	skin	skin	NOUN
dpc-1620	277	12	using	use	VERB
dpc-1620	277	13	reflectance	reflectance	NOUN
dpc-1620	277	14	confocal	confocal	ADJ
dpc-1620	277	15	microscopy	microscopy	NOUN
dpc-1620	277	16	.	.	PUNCT
dpc-1620	278	1	br	br	PROPN
dpc-1620	278	2	j	j	PROPN
dpc-1620	278	3	dermatol	dermatol	NOUN
dpc-1620	278	4	.	.	PUNCT
dpc-1620	279	1	2012	2012	NUM
dpc-1620	279	2	;	;	PUNCT
dpc-1620	279	3	167:270	167:270	NUM
dpc-1620	279	4	-	-	SYM
dpc-1620	279	5	279	279	NUM
dpc-1620	279	6	doi	doi	NOUN
dpc-1620	279	7	:	:	PUNCT
dpc-1620	279	8	10.1111	10.1111	NUM
dpc-1620	279	9	/	/	SYM
dpc-1620	279	10	j.1365	j.1365	NOUN
dpc-1620	279	11	-	-	PUNCT
dpc-1620	279	12	2133.2012.10943.x	2133.2012.10943.x	NUM
dpc-1620	279	13	.	.	PUNCT
dpc-1620	280	1	pmid	pmid	NOUN
dpc-1620	280	2	:	:	PUNCT
dpc-1620	280	3	22428802	22428802	NUM
dpc-1620	280	4	.	.	PUNCT
dpc-1620	281	1	21	21	NUM
dpc-1620	281	2	.	.	PUNCT
dpc-1620	282	1	haytoglu	haytoglu	PROPN
dpc-1620	282	2	ns	ns	PROPN
dpc-1620	282	3	,	,	PUNCT
dpc-1620	282	4	gurel	gurel	PROPN
dpc-1620	282	5	ms	ms	PROPN
dpc-1620	282	6	,	,	PUNCT
dpc-1620	282	7	erdemir	erdemir	NOUN
dpc-1620	282	8	a	a	X
dpc-1620	282	9	,	,	PUNCT
dpc-1620	282	10	et	et	PROPN
dpc-1620	282	11	al	al	PROPN
dpc-1620	282	12	.	.	PROPN
dpc-1620	282	13	assessment	assessment	NOUN
dpc-1620	282	14	of	of	ADP
dpc-1620	282	15	skin	skin	NOUN
dpc-1620	282	16	photoaging	photoage	VERB
dpc-1620	282	17	with	with	ADP
dpc-1620	282	18	reflectance	reflectance	NOUN
dpc-1620	282	19	confocal	confocal	ADJ
dpc-1620	282	20	microscopy	microscopy	NOUN
dpc-1620	282	21	.	.	PUNCT
dpc-1620	283	1	skin	skin	NOUN
dpc-1620	283	2	res	re	NOUN
dpc-1620	283	3	technol	technol	NOUN
dpc-1620	283	4	.	.	PUNCT
dpc-1620	284	1	2014;20:363	2014;20:363	NUM
dpc-1620	284	2	-	-	SYM
dpc-1620	284	3	372	372	NUM
dpc-1620	284	4	.	.	PUNCT
dpc-1620	284	5	doi	doi	NOUN
dpc-1620	284	6	:	:	PUNCT
dpc-1620	284	7	10.1111	10.1111	NUM
dpc-1620	284	8	/	/	SYM
dpc-1620	284	9	srt.12127	srt.12127	NOUN
dpc-1620	284	10	.	.	PUNCT
dpc-1620	285	1	pmid	pmid	NOUN
dpc-1620	285	2	:	:	PUNCT
dpc-1620	285	3	24506234	24506234	NUM
dpc-1620	285	4	.	.	PUNCT
dpc-1620	286	1	22	22	NUM
dpc-1620	286	2	.	.	PUNCT
dpc-1620	287	1	guida	guida	PROPN
dpc-1620	287	2	s	s	PROPN
dpc-1620	287	3	,	,	PUNCT
dpc-1620	287	4	ciardo	ciardo	NOUN
dpc-1620	287	5	s	s	NOUN
dpc-1620	287	6	,	,	PUNCT
dpc-1620	287	7	de	de	X
dpc-1620	287	8	pace	pace	NOUN
dpc-1620	287	9	b	b	NOUN
dpc-1620	287	10	,	,	PUNCT
dpc-1620	287	11	et	et	PROPN
dpc-1620	287	12	al	al	PROPN
dpc-1620	287	13	.	.	PUNCT
dpc-1620	288	1	the	the	DET
dpc-1620	288	2	influence	influence	NOUN
dpc-1620	288	3	of	of	ADP
dpc-1620	288	4	mc1r	mc1r	PROPN
dpc-1620	288	5	on	on	ADP
dpc-1620	288	6	 	 	SPACE
dpc-1620	288	7	dermal	dermal	VERB
dpc-1620	288	8	morphological	morphological	ADJ
dpc-1620	288	9	features	feature	NOUN
dpc-1620	288	10	of	of	ADP
dpc-1620	288	11	photo	photo	NOUN
dpc-1620	288	12	-	-	PUNCT
dpc-1620	288	13	exposed	expose	VERB
dpc-1620	288	14	skin	skin	NOUN
dpc-1620	288	15	in	in	ADP
dpc-1620	288	16	women	woman	NOUN
dpc-1620	288	17	revealed	reveal	VERB
dpc-1620	288	18	by	by	ADP
dpc-1620	288	19	reflectance	reflectance	NOUN
dpc-1620	288	20	confocal	confocal	ADJ
dpc-1620	288	21	microscopy	microscopy	NOUN
dpc-1620	288	22	and	and	CCONJ
dpc-1620	288	23	optical	optical	ADJ
dpc-1620	288	24	coherence	coherence	NOUN
dpc-1620	288	25	tomography	tomography	NOUN
dpc-1620	288	26	.	.	PUNCT
dpc-1620	289	1	exp	exp	NOUN
dpc-1620	289	2	dermatol	dermatol	NOUN
dpc-1620	289	3	.	.	PUNCT
dpc-1620	290	1	2019;28:1321	2019;28:1321	NUM
dpc-1620	290	2	-	-	SYM
dpc-1620	290	3	1327	1327	NUM
dpc-1620	290	4	.	.	PUNCT
dpc-1620	291	1	doi	doi	NOUN
dpc-1620	291	2	:	:	PUNCT
dpc-1620	291	3	10.1111	10.1111	NUM
dpc-1620	291	4	/	/	SYM
dpc-1620	291	5	exd.14037	exd.14037	NOUN
dpc-1620	291	6	.	.	PUNCT
dpc-1620	292	1	pmid	pmid	NOUN
dpc-1620	292	2	:	:	PUNCT
dpc-1620	292	3	31520496	31520496	NUM
dpc-1620	292	4	.	.	PUNCT
dpc-1620	293	1	23	23	NUM
dpc-1620	293	2	.	.	PUNCT
dpc-1620	294	1	guida	guida	PROPN
dpc-1620	294	2	s	s	PROPN
dpc-1620	294	3	,	,	PUNCT
dpc-1620	294	4	ciardo	ciardo	NOUN
dpc-1620	294	5	s	s	NOUN
dpc-1620	294	6	,	,	PUNCT
dpc-1620	294	7	de	de	X
dpc-1620	294	8	pace	pace	NOUN
dpc-1620	294	9	b	b	NOUN
dpc-1620	294	10	,	,	PUNCT
dpc-1620	294	11	et	et	PROPN
dpc-1620	294	12	al	al	PROPN
dpc-1620	294	13	.	.	PROPN
dpc-1620	295	1	atrophic	atrophic	ADJ
dpc-1620	295	2	and	and	CCONJ
dpc-1620	295	3	hypertrophic	hypertrophic	ADJ
dpc-1620	295	4	skin	skin	NOUN
dpc-1620	295	5	photoaging	photoage	VERB
dpc-1620	295	6	and	and	CCONJ
dpc-1620	295	7	melanocortin-1	melanocortin-1	NUM
dpc-1620	295	8	receptor	receptor	NOUN
dpc-1620	295	9	(	(	PUNCT
dpc-1620	295	10	mc1r	mc1r	PROPN
dpc-1620	295	11	):	):	PUNCT
dpc-1620	295	12	the	the	DET
dpc-1620	295	13	missing	missing	ADJ
dpc-1620	295	14	link	link	NOUN
dpc-1620	295	15	.	.	PUNCT
dpc-1620	296	1	j	j	PROPN
dpc-1620	296	2	am	be	AUX
dpc-1620	296	3	acad	acad	ADJ
dpc-1620	296	4	dermatol	dermatol	NOUN
dpc-1620	296	5	.	.	PUNCT
dpc-1620	297	1	2021;84:187	2021;84:187	NUM
dpc-1620	297	2	-	-	SYM
dpc-1620	297	3	190	190	NUM
dpc-1620	297	4	.	.	PUNCT
dpc-1620	297	5	doi	doi	NOUN
dpc-1620	297	6	:	:	PUNCT
dpc-1620	297	7	10.1016	10.1016	NUM
dpc-1620	297	8	/	/	SYM
dpc-1620	297	9	j.	j.	PROPN
dpc-1620	297	10	jaad.2020.04.075	jaad.2020.04.075	PROPN
dpc-1620	297	11	.	.	PUNCT
dpc-1620	298	1	pmid	pmid	NOUN
dpc-1620	298	2	:	:	PUNCT
dpc-1620	298	3	32335180	32335180	NUM
dpc-1620	298	4	.	.	PUNCT
dpc-1620	299	1	24	24	NUM
dpc-1620	299	2	.	.	PUNCT
dpc-1620	300	1	rajadhyaksha	rajadhyaksha	PROPN
dpc-1620	300	2	m	m	PROPN
dpc-1620	300	3	,	,	PUNCT
dpc-1620	300	4	gonzález	gonzález	PROPN
dpc-1620	300	5	s	s	PROPN
dpc-1620	300	6	,	,	PUNCT
dpc-1620	300	7	zavislan	zavislan	PROPN
dpc-1620	300	8	jm	jm	PROPN
dpc-1620	300	9	,	,	PUNCT
dpc-1620	300	10	anderson	anderson	PROPN
dpc-1620	300	11	rr	rr	PROPN
dpc-1620	300	12	,	,	PUNCT
dpc-1620	300	13	webb	webb	PROPN
dpc-1620	300	14	rh	rh	PROPN
dpc-1620	300	15	.	.	PUNCT
dpc-1620	301	1	in	in	ADP
dpc-1620	301	2	vivo	vivo	ADJ
dpc-1620	301	3	confocal	confocal	ADJ
dpc-1620	301	4	scanning	scanning	NOUN
dpc-1620	301	5	laser	laser	NOUN
dpc-1620	301	6	microscopy	microscopy	NOUN
dpc-1620	301	7	of	of	ADP
dpc-1620	301	8	human	human	ADJ
dpc-1620	301	9	skin	skin	PROPN
dpc-1620	301	10	ii	ii	PROPN
dpc-1620	301	11	:	:	PUNCT
dpc-1620	301	12	advances	advance	NOUN
dpc-1620	301	13	in	in	ADP
dpc-1620	301	14	instrumentation	instrumentation	NOUN
dpc-1620	301	15	and	and	CCONJ
dpc-1620	301	16	comparison	comparison	NOUN
dpc-1620	301	17	with	with	ADP
dpc-1620	301	18	histology	histology	NOUN
dpc-1620	301	19	.	.	PUNCT
dpc-1620	302	1	j	j	PROPN
dpc-1620	302	2	invest	invest	VERB
dpc-1620	302	3	dermatol	dermatol	NOUN
dpc-1620	302	4	.	.	PUNCT
dpc-1620	303	1	1999;113:293	1999;113:293	NUM
dpc-1620	303	2	-	-	SYM
dpc-1620	303	3	303	303	NUM
dpc-1620	303	4	.	.	PUNCT
dpc-1620	304	1	doi	doi	NOUN
dpc-1620	304	2	:	:	PUNCT
dpc-1620	304	3	10.1046	10.1046	NUM
dpc-1620	304	4	/	/	SYM
dpc-1620	304	5	j.15231747.1999.00690.x	j.15231747.1999.00690.x	NOUN
dpc-1620	304	6	.	.	PUNCT
dpc-1620	305	1	pmid	pmid	NOUN
dpc-1620	305	2	:	:	PUNCT
dpc-1620	305	3	10469324	10469324	NUM
dpc-1620	305	4	.	.	PUNCT
dpc-1620	306	1	25	25	NUM
dpc-1620	306	2	.	.	PUNCT
dpc-1620	306	3	arisi	arisi	PROPN
dpc-1620	306	4	m	m	PROPN
dpc-1620	306	5	,	,	PUNCT
dpc-1620	306	6	zane	zane	PROPN
dpc-1620	306	7	c	c	PROPN
dpc-1620	306	8	,	,	PUNCT
dpc-1620	306	9	caravello	caravello	PROPN
dpc-1620	306	10	s	s	PROPN
dpc-1620	306	11	,	,	PUNCT
dpc-1620	306	12	et	et	PROPN
dpc-1620	306	13	al	al	PROPN
dpc-1620	306	14	.	.	PROPN
dpc-1620	307	1	sun	sun	PROPN
dpc-1620	307	2	exposure	exposure	NOUN
dpc-1620	307	3	and	and	CCONJ
dpc-1620	307	4	melanoma	melanoma	NOUN
dpc-1620	307	5	,	,	PUNCT
dpc-1620	307	6	certainties	certainty	NOUN
dpc-1620	307	7	and	and	CCONJ
dpc-1620	307	8	weaknesses	weakness	NOUN
dpc-1620	307	9	of	of	ADP
dpc-1620	307	10	the	the	DET
dpc-1620	307	11	present	present	ADJ
dpc-1620	307	12	knowledge	knowledge	NOUN
dpc-1620	307	13	.	.	PUNCT
dpc-1620	308	1	front	front	ADJ
dpc-1620	308	2	med	med	PROPN
dpc-1620	308	3	(	(	PUNCT
dpc-1620	308	4	lausanne	lausanne	PROPN
dpc-1620	308	5	)	)	PUNCT
dpc-1620	308	6	.	.	PUNCT
dpc-1620	309	1	2018	2018	NUM
dpc-1620	309	2	;	;	PUNCT
dpc-1620	310	1	5:235	5:235	NUM
dpc-1620	310	2	.	.	PUNCT
dpc-1620	310	3	doi	doi	NOUN
dpc-1620	310	4	:	:	PUNCT
dpc-1620	310	5	10.3389	10.3389	NUM
dpc-1620	310	6	/	/	SYM
dpc-1620	310	7	fmed.2018.00235	fmed.2018.00235	PROPN
dpc-1620	310	8	.	.	PUNCT
dpc-1620	311	1	pmid	pmid	NOUN
dpc-1620	311	2	:	:	PUNCT
dpc-1620	311	3	30214901	30214901	NUM
dpc-1620	311	4	.	.	PUNCT
dpc-1620	312	1	26	26	NUM
dpc-1620	312	2	.	.	PUNCT
dpc-1620	312	3	suárez	suárez	PROPN
dpc-1620	312	4	b	b	PROPN
dpc-1620	312	5	,	,	PUNCT
dpc-1620	312	6	lópez	lópez	NOUN
dpc-1620	312	7	-	-	PUNCT
dpc-1620	312	8	abente	abente	NOUN
dpc-1620	312	9	g	g	NOUN
dpc-1620	312	10	,	,	PUNCT
dpc-1620	312	11	martínez	martínez	PROPN
dpc-1620	312	12	c	c	NOUN
dpc-1620	312	13	,	,	PUNCT
dpc-1620	312	14	et	et	PROPN
dpc-1620	312	15	al	al	PROPN
dpc-1620	312	16	.	.	PROPN
dpc-1620	312	17	occupation	occupation	NOUN
dpc-1620	312	18	and	and	CCONJ
dpc-1620	312	19	skin	skin	NOUN
dpc-1620	312	20	cancer	cancer	NOUN
dpc-1620	312	21	:	:	PUNCT
dpc-1620	312	22	the	the	DET
dpc-1620	312	23	results	result	NOUN
dpc-1620	312	24	of	of	ADP
dpc-1620	312	25	the	the	DET
dpc-1620	312	26	helios	helio	NOUN
dpc-1620	312	27	-	-	PUNCT
dpc-1620	312	28	i	i	PRON
dpc-1620	312	29	multicenter	multicenter	NOUN
dpc-1620	312	30	case	case	NOUN
dpc-1620	312	31	-	-	PUNCT
dpc-1620	312	32	control	control	NOUN
dpc-1620	312	33	study	study	NOUN
dpc-1620	312	34	.	.	PUNCT
dpc-1620	313	1	bmc	bmc	ADJ
dpc-1620	313	2	public	public	ADJ
dpc-1620	313	3	health	health	NOUN
dpc-1620	313	4	.	.	PUNCT
dpc-1620	314	1	2007;7:180	2007;7:180	NOUN
dpc-1620	314	2	.	.	PUNCT
dpc-1620	315	1	doi	doi	PROPN
dpc-1620	315	2	:	:	PUNCT
dpc-1620	315	3	10.1186/1471	10.1186/1471	NUM
dpc-1620	315	4	-	-	PUNCT
dpc-1620	315	5	2458	2458	NUM
dpc-1620	315	6	-	-	SYM
dpc-1620	315	7	7180	7180	NUM
dpc-1620	315	8	.	.	PUNCT
dpc-1620	316	1	pmid	pmid	NOUN
dpc-1620	316	2	:	:	PUNCT
dpc-1620	316	3	17655745	17655745	NUM
dpc-1620	316	4	.	.	PUNCT
dpc-1620	317	1	27	27	NUM
dpc-1620	317	2	.	.	PUNCT
dpc-1620	318	1	ciardo	ciardo	PROPN
dpc-1620	318	2	s	s	PROPN
dpc-1620	318	3	,	,	PUNCT
dpc-1620	318	4	pezzini	pezzini	PROPN
dpc-1620	318	5	c	c	PROPN
dpc-1620	318	6	,	,	PUNCT
dpc-1620	318	7	guida	guida	PROPN
dpc-1620	318	8	s	s	PROPN
dpc-1620	318	9	,	,	PUNCT
dpc-1620	318	10	et	et	PROPN
dpc-1620	318	11	al	al	PROPN
dpc-1620	318	12	.	.	PUNCT
dpc-1620	319	1	a	a	DET
dpc-1620	319	2	plea	plea	NOUN
dpc-1620	319	3	for	for	ADP
dpc-1620	319	4	standardization	standardization	NOUN
dpc-1620	319	5	of	of	ADP
dpc-1620	319	6	confocal	confocal	ADJ
dpc-1620	319	7	microscopy	microscopy	NOUN
dpc-1620	319	8	and	and	CCONJ
dpc-1620	319	9	optical	optical	ADJ
dpc-1620	319	10	coherence	coherence	NOUN
dpc-1620	319	11	tomography	tomography	NOUN
dpc-1620	319	12	parameters	parameter	NOUN
dpc-1620	319	13	to	to	PART
dpc-1620	319	14	evaluate	evaluate	VERB
dpc-1620	319	15	physiological	physiological	ADJ
dpc-1620	319	16	and	and	CCONJ
dpc-1620	319	17	para	para	ADJ
dpc-1620	319	18	-	-	PUNCT
dpc-1620	319	19	physiological	physiological	ADJ
dpc-1620	319	20	skin	skin	NOUN
dpc-1620	319	21	conditions	condition	NOUN
dpc-1620	319	22	in	in	ADP
dpc-1620	319	23	cosmetic	cosmetic	ADJ
dpc-1620	319	24	science	science	NOUN
dpc-1620	319	25	.	.	PUNCT
dpc-1620	320	1	exp	exp	NOUN
dpc-1620	320	2	dermatol	dermatol	NOUN
dpc-1620	320	3	.	.	PUNCT
dpc-1620	321	1	2021	2021	NUM
dpc-1620	321	2	.	.	PUNCT
dpc-1620	322	1	doi	doi	NOUN
dpc-1620	322	2	:	:	PUNCT
dpc-1620	322	3	10.1111/	10.1111/	NUM
dpc-1620	322	4	exd.14359	exd.14359	NUM
dpc-1620	322	5	.	.	PUNCT
dpc-1620	323	1	pmid	pmid	NOUN
dpc-1620	323	2	:	:	PUNCT
dpc-1620	323	3	33884663	33884663	NUM
dpc-1620	323	4	.	.	PUNCT
dpc-1620	324	1	epub	epub	NOUN
dpc-1620	324	2	ahead	ahead	ADV
dpc-1620	324	3	of	of	ADP
dpc-1620	324	4	print	print	NOUN
dpc-1620	324	5	.	.	PUNCT
dpc-1620	325	1	28	28	NUM
dpc-1620	325	2	.	.	PUNCT
dpc-1620	326	1	kawasaki	kawasaki	PROPN
dpc-1620	326	2	k	k	PROPN
dpc-1620	326	3	,	,	PUNCT
dpc-1620	326	4	yamanishi	yamanishi	NOUN
dpc-1620	326	5	k	k	PROPN
dpc-1620	326	6	,	,	PUNCT
dpc-1620	326	7	yamada	yamada	PROPN
dpc-1620	326	8	h.	h.	PROPN
dpc-1620	326	9	age	age	PROPN
dpc-1620	326	10	-	-	PUNCT
dpc-1620	326	11	related	relate	VERB
dpc-1620	326	12	morphometric	morphometric	ADJ
dpc-1620	326	13	changes	change	NOUN
dpc-1620	326	14	of	of	ADP
dpc-1620	326	15	inner	inner	ADJ
dpc-1620	326	16	structures	structure	NOUN
dpc-1620	326	17	of	of	ADP
dpc-1620	326	18	the	the	DET
dpc-1620	326	19	skin	skin	NOUN
dpc-1620	326	20	assessed	assess	VERB
dpc-1620	326	21	by	by	ADP
dpc-1620	326	22	in	in	ADP
dpc-1620	326	23	vivo	vivo	ADJ
dpc-1620	326	24	reflectance	reflectance	NOUN
dpc-1620	326	25	confocal	confocal	ADJ
dpc-1620	326	26	microscopy	microscopy	NOUN
dpc-1620	326	27	.	.	PUNCT
dpc-1620	327	1	int	int	NOUN
dpc-1620	327	2	j	j	PROPN
dpc-1620	327	3	dermatol	dermatol	NOUN
dpc-1620	327	4	.	.	PUNCT
dpc-1620	328	1	2015;54:295	2015;54:295	NUM
dpc-1620	328	2	-	-	SYM
dpc-1620	328	3	301	301	NUM
dpc-1620	328	4	.	.	PUNCT
dpc-1620	328	5	doi	doi	NOUN
dpc-1620	328	6	:	:	PUNCT
dpc-1620	328	7	10.1111	10.1111	NUM
dpc-1620	328	8	/	/	SYM
dpc-1620	328	9	ijd.12220	ijd.12220	NOUN
dpc-1620	328	10	.	.	PUNCT
dpc-1620	329	1	pmid	pmid	NOUN
dpc-1620	329	2	:	:	PUNCT
dpc-1620	329	3	25267556	25267556	NUM
dpc-1620	329	4	.	.	PUNCT
dpc-1620	330	1	29	29	NUM
dpc-1620	330	2	.	.	X
dpc-1620	331	1	fossa	fossa	VERB
dpc-1620	331	2	shirata	shirata	PROPN
dpc-1620	331	3	mm	mm	PROPN
dpc-1620	331	4	,	,	PUNCT
dpc-1620	331	5	alves	alves	PROPN
dpc-1620	331	6	gad	gad	PROPN
dpc-1620	331	7	,	,	PUNCT
dpc-1620	331	8	maia	maia	PROPN
dpc-1620	331	9	campos	campos	PROPN
dpc-1620	331	10	pmbg	pmbg	PROPN
dpc-1620	331	11	.	.	PUNCT
dpc-1620	332	1	photoageing	photoagee	VERB
dpc-1620	332	2	-	-	PUNCT
dpc-1620	332	3	related	relate	VERB
dpc-1620	332	4	skin	skin	NOUN
dpc-1620	332	5	changes	change	NOUN
dpc-1620	332	6	in	in	ADP
dpc-1620	332	7	different	different	ADJ
dpc-1620	332	8	age	age	NOUN
dpc-1620	332	9	groups	group	NOUN
dpc-1620	332	10	:	:	PUNCT
dpc-1620	332	11	a	a	DET
dpc-1620	332	12	clinical	clinical	ADJ
dpc-1620	332	13	evaluation	evaluation	NOUN
dpc-1620	332	14	by	by	ADP
dpc-1620	332	15	biophysical	biophysical	ADJ
dpc-1620	332	16	and	and	CCONJ
dpc-1620	332	17	imaging	imaging	NOUN
dpc-1620	332	18	techniques	technique	NOUN
dpc-1620	332	19	.	.	PUNCT
dpc-1620	333	1	int	int	PROPN
dpc-1620	333	2	j	j	PROPN
dpc-1620	333	3	cosmet	cosmet	PROPN
dpc-1620	333	4	sci	sci	PROPN
dpc-1620	333	5	.	.	PUNCT
dpc-1620	334	1	2019;41:265	2019;41:265	X
dpc-1620	334	2	-	-	PUNCT
dpc-1620	334	3	273	273	NUM
dpc-1620	334	4	.	.	PUNCT
dpc-1620	335	1	doi	doi	NOUN
dpc-1620	335	2	:	:	PUNCT
dpc-1620	335	3	10.1111	10.1111	NUM
dpc-1620	335	4	/	/	SYM
dpc-1620	335	5	ics.12531	ics.12531	PROPN
dpc-1620	335	6	.	.	PUNCT
dpc-1620	336	1	pmid	pmid	NOUN
dpc-1620	336	2	:	:	PUNCT
dpc-1620	336	3	30982995	30982995	NUM
dpc-1620	336	4	.	.	PUNCT
dpc-1620	337	1	30	30	NUM
dpc-1620	337	2	.	.	PUNCT
dpc-1620	338	1	bonnans	bonnan	NOUN
dpc-1620	338	2	c	c	PROPN
dpc-1620	338	3	,	,	PUNCT
dpc-1620	338	4	chou	chou	PROPN
dpc-1620	338	5	j	j	PROPN
dpc-1620	338	6	,	,	PUNCT
dpc-1620	338	7	werb	werb	ADJ
dpc-1620	338	8	z.	z.	PROPN
dpc-1620	339	1	remodelling	remodelle	VERB
dpc-1620	339	2	the	the	DET
dpc-1620	339	3	extracellular	extracellular	ADJ
dpc-1620	339	4	matrix	matrix	NOUN
dpc-1620	339	5	in	in	ADP
dpc-1620	339	6	development	development	NOUN
dpc-1620	339	7	and	and	CCONJ
dpc-1620	339	8	disease	disease	NOUN
dpc-1620	339	9	.	.	PUNCT
dpc-1620	340	1	nat	nat	PROPN
dpc-1620	340	2	rev	rev	VERB
dpc-1620	340	3	mol	mol	ADP
dpc-1620	340	4	cell	cell	NOUN
dpc-1620	340	5	biol	biol	NOUN
dpc-1620	340	6	.	.	PUNCT
dpc-1620	341	1	2014;15:786801	2014;15:786801	X
dpc-1620	341	2	.	.	X
dpc-1620	341	3	doi	doi	NOUN
dpc-1620	341	4	:	:	PUNCT
dpc-1620	341	5	10.1038	10.1038	NUM
dpc-1620	341	6	/	/	SYM
dpc-1620	341	7	nrm3904	nrm3904	ADJ
dpc-1620	341	8	.	.	PUNCT
dpc-1620	342	1	pmid	pmid	NOUN
dpc-1620	342	2	:	:	PUNCT
dpc-1620	342	3	25415508	25415508	NUM
dpc-1620	342	4	.	.	PUNCT
dpc-1620	343	1	31	31	NUM
dpc-1620	343	2	.	.	PUNCT
dpc-1620	344	1	pickup	pickup	PROPN
dpc-1620	344	2	mw	mw	PROPN
dpc-1620	344	3	,	,	PUNCT
dpc-1620	344	4	mouw	mouw	NOUN
dpc-1620	344	5	jk	jk	PROPN
dpc-1620	344	6	,	,	PUNCT
dpc-1620	344	7	weaver	weaver	PROPN
dpc-1620	344	8	vm	vm	PROPN
dpc-1620	344	9	.	.	PROPN
dpc-1620	345	1	the	the	DET
dpc-1620	345	2	extracellular	extracellular	ADJ
dpc-1620	345	3	matrix	matrix	NOUN
dpc-1620	345	4	modulates	modulate	VERB
dpc-1620	345	5	the	the	DET
dpc-1620	345	6	hallmarks	hallmark	NOUN
dpc-1620	345	7	of	of	ADP
dpc-1620	345	8	cancer	cancer	NOUN
dpc-1620	345	9	.	.	PUNCT
dpc-1620	346	1	embo	embo	PROPN
dpc-1620	346	2	rep	rep	PROPN
dpc-1620	346	3	.	.	PROPN
dpc-1620	346	4	2014;15:12431253	2014;15:12431253	NUM
dpc-1620	346	5	.	.	PUNCT
dpc-1620	347	1	doi	doi	NOUN
dpc-1620	347	2	:	:	PUNCT
dpc-1620	347	3	10.15252	10.15252	NUM
dpc-1620	347	4	/	/	SYM
dpc-1620	347	5	embr.201439246	embr.201439246	PROPN
dpc-1620	347	6	.	.	PUNCT
dpc-1620	348	1	pmid	pmid	PROPN
dpc-1620	348	2	:	:	PUNCT
dpc-1620	348	3	25381661	25381661	NUM
dpc-1620	348	4	32	32	NUM
dpc-1620	348	5	.	.	PUNCT
dpc-1620	349	1	manfredini	manfredini	PROPN
dpc-1620	349	2	m	m	PROPN
dpc-1620	349	3	,	,	PUNCT
dpc-1620	349	4	longo	longo	PROPN
dpc-1620	349	5	c	c	PROPN
dpc-1620	349	6	,	,	PUNCT
dpc-1620	349	7	ferrari	ferrari	PROPN
dpc-1620	349	8	b	b	NOUN
dpc-1620	349	9	,	,	PUNCT
dpc-1620	349	10	et	et	PROPN
dpc-1620	349	11	al	al	PROPN
dpc-1620	349	12	.	.	PROPN
dpc-1620	349	13	dermoscopic	dermoscopic	PROPN
dpc-1620	349	14	and	and	CCONJ
dpc-1620	349	15	reflectance	reflectance	NOUN
dpc-1620	349	16	confocal	confocal	ADJ
dpc-1620	349	17	microscopy	microscopy	NOUN
dpc-1620	349	18	features	feature	NOUN
dpc-1620	349	19	of	of	ADP
dpc-1620	349	20	cutaneous	cutaneous	ADJ
dpc-1620	349	21	squamous	squamous	ADJ
dpc-1620	349	22	cell	cell	NOUN
dpc-1620	349	23	carcinoma	carcinoma	NOUN
dpc-1620	349	24	.	.	PUNCT
dpc-1620	350	1	j	j	PROPN
dpc-1620	350	2	eur	eur	PROPN
dpc-1620	350	3	acad	acad	PROPN
dpc-1620	350	4	dermatol	dermatol	NOUN
dpc-1620	350	5	venereol	venereol	NOUN
dpc-1620	350	6	.	.	PUNCT
dpc-1620	351	1	2017;31:1828	2017;31:1828	NUM
dpc-1620	351	2	-	-	SYM
dpc-1620	351	3	1833	1833	NUM
dpc-1620	351	4	.	.	PUNCT
dpc-1620	352	1	doi	doi	NOUN
dpc-1620	352	2	:	:	PUNCT
dpc-1620	352	3	10.1111	10.1111	NUM
dpc-1620	352	4	/	/	SYM
dpc-1620	352	5	jdv.14463	jdv.14463	PROPN
dpc-1620	352	6	.	.	PUNCT
dpc-1620	353	1	pmid	pmid	NOUN
dpc-1620	353	2	:	:	PUNCT
dpc-1620	353	3	28696052	28696052	NUM
dpc-1620	353	4	.	.	PUNCT
dpc-1620	354	1	33	33	NUM
dpc-1620	354	2	.	.	PUNCT
dpc-1620	355	1	guida	guida	PROPN
dpc-1620	355	2	s	s	PROPN
dpc-1620	355	3	,	,	PUNCT
dpc-1620	355	4	farnetani	farnetani	X
dpc-1620	355	5	f	f	X
dpc-1620	355	6	,	,	PUNCT
dpc-1620	355	7	de	de	X
dpc-1620	355	8	pace	pace	NOUN
dpc-1620	355	9	b	b	NOUN
dpc-1620	355	10	,	,	PUNCT
dpc-1620	355	11	et	et	PROPN
dpc-1620	355	12	al	al	PROPN
dpc-1620	355	13	.	.	PUNCT
dpc-1620	355	14	flat	flat	ADV
dpc-1620	355	15	-	-	PUNCT
dpc-1620	355	16	pigmented	pigment	VERB
dpc-1620	355	17	facial	facial	ADJ
dpc-1620	355	18	lesions	lesion	NOUN
dpc-1620	355	19	without	without	ADP
dpc-1620	355	20	highly	highly	ADV
dpc-1620	355	21	specific	specific	ADJ
dpc-1620	355	22	melanocytic	melanocytic	ADJ
dpc-1620	355	23	dermoscopy	dermoscopy	NOUN
dpc-1620	355	24	features	feature	VERB
dpc-1620	355	25	:	:	PUNCT
dpc-1620	355	26	the	the	DET
dpc-1620	355	27	role	role	NOUN
dpc-1620	355	28	of	of	ADP
dpc-1620	355	29	dermoscopic	dermoscopic	ADJ
dpc-1620	355	30	globules	globule	NOUN
dpc-1620	355	31	and	and	CCONJ
dpc-1620	355	32	dots	dot	NOUN
dpc-1620	355	33	in	in	ADP
dpc-1620	355	34	differential	differential	ADJ
dpc-1620	355	35	diagnosis	diagnosis	NOUN
dpc-1620	355	36	with	with	ADP
dpc-1620	355	37	corresponding	corresponding	ADJ
dpc-1620	355	38	reflectance	reflectance	NOUN
dpc-1620	355	39	confocal	confocal	ADJ
dpc-1620	355	40	microscopy	microscopy	NOUN
dpc-1620	355	41	substrates	substrate	NOUN
dpc-1620	355	42	.	.	PUNCT
dpc-1620	356	1	j	j	PROPN
dpc-1620	356	2	eur	eur	PROPN
dpc-1620	356	3	8	8	NUM
dpc-1620	356	4	review	review	NOUN
dpc-1620	356	5	|	|	ADV
dpc-1620	356	6	dermatol	dermatol	ADJ
dpc-1620	356	7	pract	pract	NOUN
dpc-1620	356	8	concept	concept	NOUN
dpc-1620	356	9	.	.	PUNCT
dpc-1620	357	1	2021;11(3):e	2021;11(3):e	NUM
dpc-1620	357	2	2021068	2021068	NUM
dpc-1620	357	3	acad	acad	NOUN
dpc-1620	357	4	dermatol	dermatol	NOUN
dpc-1620	357	5	venereol	venereol	NOUN
dpc-1620	357	6	.	.	PUNCT
dpc-1620	358	1	2020;34	2020;34	NUM
dpc-1620	358	2	:	:	PUNCT
dpc-1620	359	1	e153	e153	PROPN
dpc-1620	359	2	-	-	PUNCT
dpc-1620	359	3	e156	e156	PROPN
dpc-1620	359	4	.	.	PUNCT
dpc-1620	359	5	doi	doi	PROPN
dpc-1620	359	6	:	:	PUNCT
dpc-1620	359	7	10.1111/	10.1111/	NUM
dpc-1620	359	8	jdv.16079	jdv.16079	X
dpc-1620	359	9	.	.	PUNCT
dpc-1620	360	1	pmid	pmid	NOUN
dpc-1620	360	2	:	:	PUNCT
dpc-1620	360	3	31729773	31729773	NUM
dpc-1620	360	4	.	.	PUNCT
dpc-1620	361	1	34	34	NUM
dpc-1620	361	2	.	.	PUNCT
dpc-1620	362	1	navarrete	navarrete	ADJ
dpc-1620	362	2	-	-	PUNCT
dpc-1620	362	3	dechent	dechent	NOUN
dpc-1620	362	4	c	c	NOUN
dpc-1620	362	5	,	,	PUNCT
dpc-1620	362	6	derosa	derosa	PROPN
dpc-1620	362	7	ap	ap	PROPN
dpc-1620	362	8	,	,	PUNCT
dpc-1620	362	9	longo	longo	PROPN
dpc-1620	362	10	c	c	PROPN
dpc-1620	362	11	,	,	PUNCT
dpc-1620	362	12	et	et	PROPN
dpc-1620	362	13	al	al	PROPN
dpc-1620	362	14	.	.	PROPN
dpc-1620	363	1	reflectance	reflectance	NOUN
dpc-1620	363	2	confocal	confocal	ADJ
dpc-1620	363	3	microscopy	microscopy	NOUN
dpc-1620	363	4	terminology	terminology	NOUN
dpc-1620	363	5	glossary	glossary	NOUN
dpc-1620	363	6	for	for	ADP
dpc-1620	363	7	nonmelanocytic	nonmelanocytic	ADJ
dpc-1620	363	8	skin	skin	NOUN
dpc-1620	363	9	lesions	lesion	NOUN
dpc-1620	363	10	:	:	PUNCT
dpc-1620	363	11	a	a	DET
dpc-1620	363	12	 	 	SPACE
dpc-1620	363	13	systematic	systematic	ADJ
dpc-1620	363	14	review	review	NOUN
dpc-1620	363	15	.	.	PUNCT
dpc-1620	364	1	j	j	PROPN
dpc-1620	364	2	am	be	AUX
dpc-1620	364	3	acad	acad	ADJ
dpc-1620	364	4	dermatol	dermatol	NOUN
dpc-1620	364	5	.	.	PUNCT
dpc-1620	365	1	2019;80:1414	2019;80:1414	NUM
dpc-1620	365	2	-	-	SYM
dpc-1620	365	3	1427.e3	1427.e3	NUM
dpc-1620	365	4	.	.	PUNCT
dpc-1620	366	1	doi	doi	NOUN
dpc-1620	366	2	:	:	PUNCT
dpc-1620	366	3	10.1016	10.1016	NUM
dpc-1620	366	4	/	/	SYM
dpc-1620	366	5	j.jaad.2018.12.007	j.jaad.2018.12.007	NOUN
dpc-1620	366	6	.	.	PUNCT
dpc-1620	367	1	pmid	pmid	NOUN
dpc-1620	367	2	:	:	PUNCT
dpc-1620	367	3	30529706	30529706	NUM
dpc-1620	367	4	.	.	PUNCT
dpc-1620	368	1	35	35	NUM
dpc-1620	368	2	.	.	PUNCT
dpc-1620	369	1	lupu	lupu	PROPN
dpc-1620	369	2	m	m	PROPN
dpc-1620	369	3	,	,	PUNCT
dpc-1620	369	4	caruntu	caruntu	VERB
dpc-1620	369	5	c	c	NOUN
dpc-1620	369	6	,	,	PUNCT
dpc-1620	369	7	popa	popa	NOUN
dpc-1620	369	8	mi	mi	PROPN
dpc-1620	369	9	,	,	PUNCT
dpc-1620	369	10	voiculescu	voiculescu	PROPN
dpc-1620	369	11	vm	vm	PROPN
dpc-1620	369	12	,	,	PUNCT
dpc-1620	369	13	zurac	zurac	PROPN
dpc-1620	369	14	s	s	PROPN
dpc-1620	369	15	,	,	PUNCT
dpc-1620	369	16	boda	boda	PROPN
dpc-1620	369	17	d.	d.	NOUN
dpc-1620	369	18	vascular	vascular	NOUN
dpc-1620	369	19	patterns	pattern	NOUN
dpc-1620	369	20	in	in	ADP
dpc-1620	369	21	basal	basal	ADJ
dpc-1620	369	22	cell	cell	NOUN
dpc-1620	369	23	carcinoma	carcinoma	NOUN
dpc-1620	369	24	:	:	PUNCT
dpc-1620	369	25	dermoscopic	dermoscopic	NOUN
dpc-1620	369	26	,	,	PUNCT
dpc-1620	369	27	confocal	confocal	ADJ
dpc-1620	369	28	and	and	CCONJ
dpc-1620	369	29	histopathological	histopathological	ADJ
dpc-1620	369	30	perspectives	perspective	NOUN
dpc-1620	369	31	.	.	PUNCT
dpc-1620	370	1	oncol	oncol	ADJ
dpc-1620	370	2	lett	lett	PROPN
dpc-1620	370	3	.	.	PUNCT
dpc-1620	371	1	2019;17:41124125	2019;17:41124125	NUM
dpc-1620	371	2	.	.	PUNCT
dpc-1620	372	1	doi	doi	NOUN
dpc-1620	372	2	:	:	PUNCT
dpc-1620	372	3	10.3892	10.3892	NUM
dpc-1620	372	4	/	/	SYM
dpc-1620	372	5	ol.2019.10070	ol.2019.10070	NOUN
dpc-1620	372	6	.	.	PUNCT
dpc-1620	373	1	pmid	pmid	NOUN
dpc-1620	373	2	:	:	PUNCT
dpc-1620	373	3	30944604	30944604	NUM
dpc-1620	373	4	.	.	PUNCT
dpc-1620	374	1	36	36	NUM
dpc-1620	374	2	.	.	PUNCT
dpc-1620	375	1	rishpon	rishpon	PROPN
dpc-1620	375	2	a	a	PRON
dpc-1620	375	3	,	,	PUNCT
dpc-1620	375	4	kim	kim	PROPN
dpc-1620	375	5	n	n	CCONJ
dpc-1620	375	6	,	,	PUNCT
dpc-1620	375	7	scope	scope	VERB
dpc-1620	375	8	a	a	PRON
dpc-1620	375	9	,	,	PUNCT
dpc-1620	376	1	et	et	PROPN
dpc-1620	376	2	al	al	PROPN
dpc-1620	376	3	.	.	PROPN
dpc-1620	377	1	reflectance	reflectance	NOUN
dpc-1620	377	2	confocal	confocal	ADJ
dpc-1620	377	3	microscopy	microscopy	NOUN
dpc-1620	377	4	criteria	criterion	NOUN
dpc-1620	377	5	for	for	ADP
dpc-1620	377	6	squamous	squamous	ADJ
dpc-1620	377	7	cell	cell	NOUN
dpc-1620	377	8	carcinomas	carcinoma	NOUN
dpc-1620	377	9	and	and	CCONJ
dpc-1620	377	10	actinic	actinic	ADJ
dpc-1620	377	11	keratoses	keratose	NOUN
dpc-1620	377	12	.	.	PUNCT
dpc-1620	378	1	arch	arch	ADJ
dpc-1620	378	2	dermatol	dermatol	NOUN
dpc-1620	378	3	.	.	PUNCT
dpc-1620	379	1	2009;145:766	2009;145:766	NUM
dpc-1620	379	2	-	-	SYM
dpc-1620	379	3	772	772	NUM
dpc-1620	379	4	.	.	PUNCT
dpc-1620	379	5	doi	doi	NOUN
dpc-1620	379	6	:	:	PUNCT
dpc-1620	379	7	10.1001	10.1001	NUM
dpc-1620	379	8	/	/	SYM
dpc-1620	379	9	archdermatol.2009.134	archdermatol.2009.134	PROPN
dpc-1620	379	10	.	.	PUNCT
dpc-1620	380	1	pmid	pmid	NOUN
dpc-1620	380	2	:	:	PUNCT
dpc-1620	380	3	19620557	19620557	NUM
dpc-1620	380	4	.	.	PUNCT
dpc-1620	381	1	37	37	NUM
dpc-1620	381	2	.	.	PUNCT
dpc-1620	382	1	segura	segura	PROPN
dpc-1620	382	2	s	s	PROPN
dpc-1620	382	3	,	,	PUNCT
dpc-1620	382	4	puig	puig	PROPN
dpc-1620	382	5	s	s	PROPN
dpc-1620	382	6	,	,	PUNCT
dpc-1620	382	7	carrera	carrera	PROPN
dpc-1620	382	8	c	c	PROPN
dpc-1620	382	9	,	,	PUNCT
dpc-1620	382	10	palou	palou	PROPN
dpc-1620	382	11	j	j	PROPN
dpc-1620	382	12	,	,	PUNCT
dpc-1620	382	13	malvehy	malvehy	PROPN
dpc-1620	382	14	j.	j.	PROPN
dpc-1620	382	15	dendritic	dendritic	PROPN
dpc-1620	382	16	cells	cell	NOUN
dpc-1620	382	17	in	in	ADP
dpc-1620	382	18	pigmented	pigment	VERB
dpc-1620	382	19	basal	basal	NOUN
dpc-1620	382	20	cell	cell	NOUN
dpc-1620	382	21	carcinoma	carcinoma	NOUN
dpc-1620	382	22	:	:	PUNCT
dpc-1620	382	23	a	a	DET
dpc-1620	382	24	relevant	relevant	ADJ
dpc-1620	382	25	finding	finding	NOUN
dpc-1620	382	26	by	by	ADP
dpc-1620	382	27	reflectance	reflectance	NOUN
dpc-1620	382	28	-	-	PUNCT
dpc-1620	382	29	mode	mode	NOUN
dpc-1620	382	30	confocal	confocal	ADJ
dpc-1620	382	31	microscopy	microscopy	NOUN
dpc-1620	382	32	.	.	PUNCT
dpc-1620	383	1	arch	arch	ADJ
dpc-1620	383	2	dermatol	dermatol	NOUN
dpc-1620	383	3	.	.	PUNCT
dpc-1620	384	1	2007;143:883886	2007;143:883886	NUM
dpc-1620	384	2	.	.	PUNCT
dpc-1620	385	1	doi	doi	NOUN
dpc-1620	385	2	:	:	PUNCT
dpc-1620	385	3	10.1001	10.1001	NUM
dpc-1620	385	4	/	/	SYM
dpc-1620	385	5	archderm.143.7.883	archderm.143.7.883	PROPN
dpc-1620	385	6	.	.	PUNCT
dpc-1620	386	1	pmid	pmid	NOUN
dpc-1620	386	2	:	:	PUNCT
dpc-1620	386	3	17638732	17638732	NUM
dpc-1620	386	4	.	.	PUNCT
dpc-1620	387	1	38	38	NUM
dpc-1620	387	2	.	.	PUNCT
dpc-1620	387	3	agero	agero	PROPN
dpc-1620	387	4	al	al	PROPN
dpc-1620	387	5	,	,	PUNCT
dpc-1620	387	6	busam	busam	PROPN
dpc-1620	387	7	kj	kj	PROPN
dpc-1620	387	8	,	,	PUNCT
dpc-1620	387	9	benvenuto	benvenuto	PROPN
dpc-1620	387	10	-	-	PUNCT
dpc-1620	387	11	andrade	andrade	PROPN
dpc-1620	387	12	c	c	NOUN
dpc-1620	387	13	,	,	PUNCT
dpc-1620	387	14	et	et	PROPN
dpc-1620	387	15	al	al	PROPN
dpc-1620	387	16	.	.	PROPN
dpc-1620	387	17	reflectance	reflectance	NOUN
dpc-1620	387	18	confocal	confocal	ADJ
dpc-1620	387	19	microscopy	microscopy	NOUN
dpc-1620	387	20	of	of	ADP
dpc-1620	387	21	pigmented	pigment	VERB
dpc-1620	387	22	basal	basal	NOUN
dpc-1620	387	23	cell	cell	NOUN
dpc-1620	387	24	carcinoma	carcinoma	NOUN
dpc-1620	387	25	.	.	PUNCT
dpc-1620	388	1	j	j	PROPN
dpc-1620	388	2	am	be	AUX
dpc-1620	388	3	acad	acad	ADJ
dpc-1620	388	4	dermatol	dermatol	NOUN
dpc-1620	388	5	.	.	PUNCT
dpc-1620	389	1	2006;54:638	2006;54:638	NUM
dpc-1620	389	2	-	-	PUNCT
dpc-1620	389	3	643	643	NUM
dpc-1620	389	4	.	.	PUNCT
dpc-1620	389	5	doi	doi	NOUN
dpc-1620	389	6	:	:	PUNCT
dpc-1620	389	7	10.1016	10.1016	NUM
dpc-1620	389	8	/	/	SYM
dpc-1620	389	9	j.	j.	PROPN
dpc-1620	389	10	jaad.2005.11.1096	jaad.2005.11.1096	PROPN
dpc-1620	389	11	.	.	PUNCT
dpc-1620	390	1	pmid	pmid	NOUN
dpc-1620	390	2	:	:	PUNCT
dpc-1620	390	3	16546585	16546585	NUM
dpc-1620	390	4	.	.	PUNCT
dpc-1620	391	1	39	39	NUM
dpc-1620	391	2	.	.	PUNCT
dpc-1620	392	1	spathis	spathis	PROPN
dpc-1620	392	2	a	a	PROPN
dpc-1620	392	3	,	,	PUNCT
dpc-1620	392	4	katoulis	katoulis	PROPN
dpc-1620	392	5	ac	ac	PROPN
dpc-1620	392	6	,	,	PUNCT
dpc-1620	392	7	damaskou	damaskou	PROPN
dpc-1620	392	8	v	v	NUM
dpc-1620	392	9	,	,	PUNCT
dpc-1620	392	10	et	et	PROPN
dpc-1620	392	11	al	al	PROPN
dpc-1620	392	12	.	.	PROPN
dpc-1620	392	13	 	 	SPACE
dpc-1620	392	14	braf	braf	NOUN
dpc-1620	392	15	 	 	SPACE
dpc-1620	392	16	mutation	mutation	NOUN
dpc-1620	392	17	status	status	NOUN
dpc-1620	392	18	in	in	ADP
dpc-1620	392	19	primary	primary	ADJ
dpc-1620	392	20	,	,	PUNCT
dpc-1620	392	21	recurrent	recurrent	NOUN
dpc-1620	392	22	,	,	PUNCT
dpc-1620	392	23	and	and	CCONJ
dpc-1620	392	24	metastatic	metastatic	ADJ
dpc-1620	392	25	malignant	malignant	ADJ
dpc-1620	392	26	melanoma	melanoma	NOUN
dpc-1620	392	27	and	and	CCONJ
dpc-1620	392	28	its	its	PRON
dpc-1620	392	29	relation	relation	NOUN
dpc-1620	392	30	to	to	ADP
dpc-1620	392	31	histopathological	histopathological	ADJ
dpc-1620	392	32	parameters	parameter	NOUN
dpc-1620	392	33	.	.	PUNCT
dpc-1620	393	1	dermatol	dermatol	NOUN
dpc-1620	393	2	pract	pract	PROPN
dpc-1620	393	3	concept	concept	NOUN
dpc-1620	393	4	.	.	PUNCT
dpc-1620	394	1	2019;9:54	2019;9:54	NOUN
dpc-1620	394	2	-	-	PUNCT
dpc-1620	394	3	62	62	NUM
dpc-1620	394	4	.	.	PUNCT
dpc-1620	395	1	doi	doi	NOUN
dpc-1620	395	2	:	:	PUNCT
dpc-1620	395	3	10.5826	10.5826	NUM
dpc-1620	395	4	/	/	SYM
dpc-1620	395	5	dpc.0901a13	dpc.0901a13	NOUN
dpc-1620	395	6	.	.	PUNCT
dpc-1620	396	1	pmid	pmid	NOUN
dpc-1620	396	2	:	:	PUNCT
dpc-1620	396	3	30775150	30775150	NUM
dpc-1620	396	4	.	.	PUNCT
dpc-1620	397	1	40	40	NUM
dpc-1620	397	2	.	.	PUNCT
dpc-1620	398	1	kaur	kaur	PROPN
dpc-1620	398	2	a	a	PROPN
dpc-1620	398	3	,	,	PUNCT
dpc-1620	398	4	ecker	ecker	PROPN
dpc-1620	398	5	bl	bl	PROPN
dpc-1620	398	6	,	,	PUNCT
dpc-1620	398	7	douglass	douglass	PROPN
dpc-1620	398	8	sm	sm	PROPN
dpc-1620	398	9	,	,	PUNCT
dpc-1620	398	10	et	et	PROPN
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dpc-1620	398	12	.	.	PUNCT
dpc-1620	399	1	remodeling	remodeling	NOUN
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dpc-1620	399	3	the	the	DET
dpc-1620	399	4	collagen	collagen	NOUN
dpc-1620	399	5	matrix	matrix	NOUN
dpc-1620	399	6	in	in	ADP
dpc-1620	399	7	aging	age	VERB
dpc-1620	399	8	skin	skin	NOUN
dpc-1620	399	9	promotes	promote	VERB
dpc-1620	399	10	melanoma	melanoma	NOUN
dpc-1620	399	11	metastasis	metastasis	NOUN
dpc-1620	399	12	and	and	CCONJ
dpc-1620	399	13	affects	affect	VERB
dpc-1620	399	14	immune	immune	ADJ
dpc-1620	399	15	cell	cell	NOUN
dpc-1620	399	16	motility	motility	NOUN
dpc-1620	399	17	.	.	PUNCT
dpc-1620	400	1	cancer	cancer	NOUN
dpc-1620	400	2	discov	discov	PROPN
dpc-1620	400	3	.	.	PUNCT
dpc-1620	401	1	2019;9:64	2019;9:64	PROPN
dpc-1620	401	2	-	-	PUNCT
dpc-1620	401	3	81	81	NUM
dpc-1620	401	4	.	.	PUNCT
dpc-1620	402	1	doi	doi	NOUN
dpc-1620	402	2	:	:	PUNCT
dpc-1620	402	3	10.1158/2159	10.1158/2159	NUM
dpc-1620	402	4	-	-	PUNCT
dpc-1620	402	5	8290.cd-18	8290.cd-18	NUM
dpc-1620	402	6	-	-	PUNCT
dpc-1620	402	7	0193.pmid	0193.pmid	NOUN
dpc-1620	402	8	:	:	PUNCT
dpc-1620	402	9	30279173	30279173	NUM
dpc-1620	402	10	.	.	PUNCT
dpc-1620	403	1	41	41	NUM
dpc-1620	403	2	.	.	PUNCT
dpc-1620	404	1	tagliabue	tagliabue	PROPN
dpc-1620	404	2	e	e	NOUN
dpc-1620	404	3	,	,	PUNCT
dpc-1620	404	4	gandini	gandini	VERB
dpc-1620	404	5	s	s	NOUN
dpc-1620	404	6	,	,	PUNCT
dpc-1620	404	7	garcía	garcía	ADJ
dpc-1620	404	8	-	-	PUNCT
dpc-1620	404	9	borrón	borrón	PROPN
dpc-1620	404	10	jc	jc	PROPN
dpc-1620	404	11	,	,	PUNCT
dpc-1620	404	12	et	et	PROPN
dpc-1620	404	13	al	al	PROPN
dpc-1620	404	14	.	.	PROPN
dpc-1620	404	15	association	association	PROPN
dpc-1620	404	16	of	of	ADP
dpc-1620	404	17	melanocortin-1	melanocortin-1	NUM
dpc-1620	404	18	receptor	receptor	NOUN
dpc-1620	404	19	variants	variant	NOUN
dpc-1620	404	20	with	with	ADP
dpc-1620	404	21	pigmentary	pigmentary	ADJ
dpc-1620	404	22	traits	trait	NOUN
dpc-1620	404	23	in	in	ADP
dpc-1620	404	24	humans	human	NOUN
dpc-1620	404	25	:	:	PUNCT
dpc-1620	404	26	a	a	PRON
dpc-1620	404	27	 	 	SPACE
dpc-1620	404	28	pooled	pool	VERB
dpc-1620	404	29	analysis	analysis	NOUN
dpc-1620	404	30	from	from	ADP
dpc-1620	404	31	the	the	DET
dpc-1620	404	32	m	m	NOUN
dpc-1620	404	33	-	-	PUNCT
dpc-1620	404	34	skip	skip	ADJ
dpc-1620	404	35	project	project	NOUN
dpc-1620	404	36	.	.	PUNCT
dpc-1620	405	1	j	j	PROPN
dpc-1620	405	2	invest	invest	VERB
dpc-1620	405	3	dermatol	dermatol	NOUN
dpc-1620	405	4	.	.	PUNCT
dpc-1620	406	1	2016;136:1914	2016;136:1914	NUM
dpc-1620	406	2	-	-	SYM
dpc-1620	406	3	1917	1917	NUM
dpc-1620	406	4	.	.	PUNCT
dpc-1620	407	1	doi	doi	NOUN
dpc-1620	407	2	:	:	PUNCT
dpc-1620	407	3	10.1016	10.1016	NUM
dpc-1620	407	4	/	/	SYM
dpc-1620	407	5	j.jid.2016.05.099	j.jid.2016.05.099	ADJ
dpc-1620	407	6	.	.	PUNCT
dpc-1620	408	1	pmid	pmid	NOUN
dpc-1620	408	2	:	:	PUNCT
dpc-1620	408	3	27251790	27251790	NUM
dpc-1620	408	4	.	.	PUNCT
dpc-1620	409	1	42	42	NUM
dpc-1620	409	2	.	.	PUNCT
dpc-1620	410	1	tagliabue	tagliabue	PROPN
dpc-1620	410	2	e	e	NOUN
dpc-1620	410	3	,	,	PUNCT
dpc-1620	410	4	gandini	gandini	VERB
dpc-1620	410	5	s	s	PROPN
dpc-1620	410	6	,	,	PUNCT
dpc-1620	410	7	bellocco	bellocco	NOUN
dpc-1620	410	8	r	r	NOUN
dpc-1620	410	9	,	,	PUNCT
dpc-1620	410	10	et	et	PROPN
dpc-1620	410	11	al	al	PROPN
dpc-1620	410	12	.	.	PUNCT
dpc-1620	411	1	mc1r	mc1r	PROPN
dpc-1620	411	2	variants	variant	NOUN
dpc-1620	411	3	as	as	ADP
dpc-1620	411	4	melanoma	melanoma	NOUN
dpc-1620	411	5	risk	risk	NOUN
dpc-1620	411	6	factors	factor	NOUN
dpc-1620	411	7	independent	independent	ADJ
dpc-1620	411	8	of	of	ADP
dpc-1620	411	9	at	at	ADP
dpc-1620	411	10	-	-	PUNCT
dpc-1620	411	11	risk	risk	NOUN
dpc-1620	411	12	phenotypic	phenotypic	NOUN
dpc-1620	411	13	characteristics	characteristic	NOUN
dpc-1620	411	14	:	:	PUNCT
dpc-1620	411	15	a	a	DET
dpc-1620	411	16	pooled	pool	VERB
dpc-1620	411	17	analysis	analysis	NOUN
dpc-1620	411	18	from	from	ADP
dpc-1620	411	19	the	the	DET
dpc-1620	411	20	m	m	NOUN
dpc-1620	411	21	-	-	PUNCT
dpc-1620	411	22	skip	skip	ADJ
dpc-1620	411	23	project	project	NOUN
dpc-1620	411	24	.	.	PUNCT
dpc-1620	412	1	cancer	cancer	NOUN
dpc-1620	412	2	manag	manag	NOUN
dpc-1620	412	3	res	re	NOUN
dpc-1620	412	4	.	.	PUNCT
dpc-1620	413	1	2018;10:1143	2018;10:1143	NOUN
dpc-1620	413	2	-	-	NOUN
dpc-1620	413	3	1154	1154	NUM
dpc-1620	413	4	.	.	PUNCT
dpc-1620	414	1	doi	doi	NOUN
dpc-1620	414	2	:	:	PUNCT
dpc-1620	414	3	10.2147	10.2147	NUM
dpc-1620	414	4	/	/	SYM
dpc-1620	414	5	cmar.s155283	cmar.s155283	NOUN
dpc-1620	414	6	.	.	PUNCT
dpc-1620	415	1	pmid	pmid	NOUN
dpc-1620	415	2	:	:	PUNCT
dpc-1620	415	3	29795986	29795986	NUM
dpc-1620	415	4	.	.	PUNCT
dpc-1620	416	1	43	43	NUM
dpc-1620	416	2	.	.	PUNCT
dpc-1620	417	1	tagliabue	tagliabue	PROPN
dpc-1620	417	2	e	e	NOUN
dpc-1620	417	3	,	,	PUNCT
dpc-1620	417	4	fargnoli	fargnoli	PROPN
dpc-1620	417	5	mc	mc	PROPN
dpc-1620	417	6	,	,	PUNCT
dpc-1620	417	7	gandini	gandini	VERB
dpc-1620	417	8	s	s	PROPN
dpc-1620	417	9	,	,	PUNCT
dpc-1620	417	10	et	et	PROPN
dpc-1620	417	11	al	al	PROPN
dpc-1620	417	12	.	.	PUNCT
dpc-1620	418	1	mc1r	mc1r	PROPN
dpc-1620	418	2	gene	gene	NOUN
dpc-1620	418	3	variants	variant	NOUN
dpc-1620	418	4	and	and	CCONJ
dpc-1620	418	5	non	non	ADJ
dpc-1620	418	6	-	-	ADJ
dpc-1620	418	7	melanoma	melanoma	ADJ
dpc-1620	418	8	skin	skin	NOUN
dpc-1620	418	9	cancer	cancer	NOUN
dpc-1620	418	10	:	:	PUNCT
dpc-1620	418	11	a	a	DET
dpc-1620	418	12	pooled	pool	VERB
dpc-1620	418	13	-	-	PUNCT
dpc-1620	418	14	analysis	analysis	NOUN
dpc-1620	418	15	from	from	ADP
dpc-1620	418	16	the	the	DET
dpc-1620	418	17	m	m	NOUN
dpc-1620	418	18	-	-	PUNCT
dpc-1620	418	19	skip	skip	ADJ
dpc-1620	418	20	project	project	NOUN
dpc-1620	418	21	.	.	PUNCT
dpc-1620	419	1	br	br	PROPN
dpc-1620	419	2	j	j	PROPN
dpc-1620	419	3	cancer	cancer	NOUN
dpc-1620	419	4	.	.	PUNCT
dpc-1620	420	1	2015;113:354	2015;113:354	NUM
dpc-1620	420	2	-	-	SYM
dpc-1620	420	3	363	363	NUM
dpc-1620	420	4	.	.	PUNCT
dpc-1620	421	1	doi	doi	NOUN
dpc-1620	421	2	:	:	PUNCT
dpc-1620	421	3	10.1038/	10.1038/	NUM
dpc-1620	421	4	bjc.2015.231	bjc.2015.231	PROPN
dpc-1620	421	5	.	.	PUNCT
dpc-1620	422	1	pmid	pmid	NOUN
dpc-1620	422	2	:	:	PUNCT
dpc-1620	422	3	26103569	26103569	NUM
dpc-1620	422	4	.	.	PUNCT