id	sid	tid	token	lemma	pos
dpc-2310	1	1	dermatology	dermatology	NOUN
dpc-2310	1	2	:	:	PUNCT
dpc-2310	1	3	practical	practical	ADJ
dpc-2310	1	4	and	and	CCONJ
dpc-2310	1	5	conceptual	conceptual	ADJ
dpc-2310	1	6	review	review	NOUN
dpc-2310	1	7	|	|	ADV
dpc-2310	1	8	dermatol	dermatol	ADJ
dpc-2310	1	9	pract	pract	NOUN
dpc-2310	1	10	concept	concept	NOUN
dpc-2310	1	11	.	.	PUNCT
dpc-2310	2	1	2022;12(1):e2022155	2022;12(1):e2022155	NUM
dpc-2310	2	2	1	1	NUM
dpc-2310	2	3	topical	topical	ADJ
dpc-2310	2	4	and	and	CCONJ
dpc-2310	2	5	conventional	conventional	ADJ
dpc-2310	2	6	systemic	systemic	ADJ
dpc-2310	2	7	treatments	treatment	NOUN
dpc-2310	2	8	in	in	ADP
dpc-2310	2	9	atopic	atopic	NOUN
dpc-2310	2	10	dermatitis	dermatitis	NOUN
dpc-2310	2	11	:	:	PUNCT
dpc-2310	2	12	have	have	AUX
dpc-2310	2	13	they	they	PRON
dpc-2310	2	14	gone	go	VERB
dpc-2310	2	15	out	out	ADP
dpc-2310	2	16	of	of	ADP
dpc-2310	2	17	fashion	fashion	NOUN
dpc-2310	2	18	?	?	PUNCT
dpc-2310	3	1	giulia	giulia	PROPN
dpc-2310	3	2	calabrese1	calabrese1	PROPN
dpc-2310	3	3	,	,	PUNCT
dpc-2310	3	4	gaetano	gaetano	PROPN
dpc-2310	3	5	licata1	licata1	PROPN
dpc-2310	3	6	,	,	PUNCT
dpc-2310	3	7	alessio	alessio	PROPN
dpc-2310	3	8	gambardella1	gambardella1	PROPN
dpc-2310	3	9	,	,	PUNCT
dpc-2310	3	10	alina	alina	PROPN
dpc-2310	3	11	de	de	X
dpc-2310	3	12	rosa1	rosa1	PROPN
dpc-2310	3	13	,	,	PUNCT
dpc-2310	3	14	roberto	roberto	PROPN
dpc-2310	3	15	alfano2	alfano2	PROPN
dpc-2310	3	16	,	,	PUNCT
dpc-2310	3	17	giuseppe	giuseppe	PROPN
dpc-2310	3	18	argenziano1	argenziano1	PROPN
dpc-2310	3	19	1	1	NUM
dpc-2310	3	20	dermatology	dermatology	NOUN
dpc-2310	3	21	unit	unit	NOUN
dpc-2310	3	22	,	,	PUNCT
dpc-2310	3	23	department	department	NOUN
dpc-2310	3	24	of	of	ADP
dpc-2310	3	25	mental	mental	ADJ
dpc-2310	3	26	and	and	CCONJ
dpc-2310	3	27	physical	physical	ADJ
dpc-2310	3	28	health	health	NOUN
dpc-2310	3	29	and	and	CCONJ
dpc-2310	3	30	preventive	preventive	ADJ
dpc-2310	3	31	medicine	medicine	NOUN
dpc-2310	3	32	,	,	PUNCT
dpc-2310	3	33	university	university	PROPN
dpc-2310	3	34	of	of	ADP
dpc-2310	3	35	campania	campania	PROPN
dpc-2310	3	36	luigi	luigi	PROPN
dpc-2310	3	37	vanvitelli	vanvitelli	PROPN
dpc-2310	3	38	,	,	PUNCT
dpc-2310	3	39	naples	naples	PROPN
dpc-2310	3	40	,	,	PUNCT
dpc-2310	3	41	italy	italy	PROPN
dpc-2310	3	42	2	2	NUM
dpc-2310	3	43	department	department	NOUN
dpc-2310	3	44	of	of	ADP
dpc-2310	3	45	anesthesiology	anesthesiology	NOUN
dpc-2310	3	46	surgery	surgery	NOUN
dpc-2310	3	47	and	and	CCONJ
dpc-2310	3	48	emergency	emergency	NOUN
dpc-2310	3	49	,	,	PUNCT
dpc-2310	3	50	university	university	PROPN
dpc-2310	3	51	of	of	ADP
dpc-2310	3	52	campania	campania	PROPN
dpc-2310	3	53	luigi	luigi	PROPN
dpc-2310	3	54	vanvitelli	vanvitelli	PROPN
dpc-2310	3	55	,	,	PUNCT
dpc-2310	3	56	naples	naples	PROPN
dpc-2310	3	57	,	,	PUNCT
dpc-2310	3	58	italy	italy	PROPN
dpc-2310	3	59	.	.	PUNCT
dpc-2310	4	1	keywords	keyword	NOUN
dpc-2310	4	2	:	:	PUNCT
dpc-2310	4	3	atopic	atopic	NOUN
dpc-2310	4	4	dermatitis	dermatitis	NOUN
dpc-2310	4	5	,	,	PUNCT
dpc-2310	4	6	treatments	treatment	NOUN
dpc-2310	4	7	,	,	PUNCT
dpc-2310	4	8	therapy	therapy	NOUN
dpc-2310	4	9	,	,	PUNCT
dpc-2310	4	10	topicals	topical	NOUN
dpc-2310	4	11	,	,	PUNCT
dpc-2310	4	12	systemic	systemic	ADJ
dpc-2310	4	13	therapy	therapy	NOUN
dpc-2310	4	14	citation	citation	NOUN
dpc-2310	4	15	:	:	PUNCT
dpc-2310	4	16	calabrese	calabrese	ADJ
dpc-2310	4	17	g	g	PROPN
dpc-2310	4	18	,	,	PUNCT
dpc-2310	4	19	licata	licata	VERB
dpc-2310	4	20	g	g	NOUN
dpc-2310	4	21	,	,	PUNCT
dpc-2310	4	22	gambardella	gambardella	VERB
dpc-2310	4	23	a	a	DET
dpc-2310	4	24	,	,	PUNCT
dpc-2310	4	25	de	de	PROPN
dpc-2310	4	26	rosa	rosa	PROPN
dpc-2310	4	27	a	a	PROPN
dpc-2310	4	28	,	,	PUNCT
dpc-2310	4	29	alfano	alfano	NOUN
dpc-2310	4	30	r	r	NOUN
dpc-2310	4	31	,	,	PUNCT
dpc-2310	4	32	argenziano	argenziano	ADJ
dpc-2310	4	33	g.	g.	NOUN
dpc-2310	4	34	dermatol	dermatol	PROPN
dpc-2310	4	35	pract	pract	PROPN
dpc-2310	4	36	concept	concept	NOUN
dpc-2310	4	37	.	.	PUNCT
dpc-2310	5	1	2022;12(1):e2022155	2022;12(1):e2022155	X
dpc-2310	5	2	.	.	PUNCT
dpc-2310	5	3	doi	doi	PROPN
dpc-2310	5	4	:	:	PUNCT
dpc-2310	5	5	https://doi.org/10.5826/dpc.1201a155	https://doi.org/10.5826/dpc.1201a155	PROPN
dpc-2310	5	6	accepted	accept	VERB
dpc-2310	5	7	:	:	PUNCT
dpc-2310	5	8	january	january	PROPN
dpc-2310	5	9	7	7	NUM
dpc-2310	5	10	,	,	PUNCT
dpc-2310	5	11	2022	2022	NUM
dpc-2310	5	12	;	;	PUNCT
dpc-2310	5	13	published	publish	VERB
dpc-2310	5	14	:	:	PUNCT
dpc-2310	5	15	january	january	PROPN
dpc-2310	5	16	2022	2022	NUM
dpc-2310	6	1	copyright	copyright	NOUN
dpc-2310	6	2	:	:	PUNCT
dpc-2310	6	3	©	©	PROPN
dpc-2310	6	4	2022	2022	NUM
dpc-2310	6	5	calabrese	calabrese	NOUN
dpc-2310	6	6	et	et	PROPN
dpc-2310	6	7	al	al	PROPN
dpc-2310	6	8	.	.	PUNCT
dpc-2310	7	1	this	this	PRON
dpc-2310	7	2	is	be	AUX
dpc-2310	7	3	an	an	DET
dpc-2310	7	4	open	open	ADJ
dpc-2310	7	5	-	-	PUNCT
dpc-2310	7	6	access	access	NOUN
dpc-2310	7	7	article	article	NOUN
dpc-2310	7	8	distributed	distribute	VERB
dpc-2310	7	9	under	under	ADP
dpc-2310	7	10	the	the	DET
dpc-2310	7	11	terms	term	NOUN
dpc-2310	7	12	of	of	ADP
dpc-2310	7	13	the	the	DET
dpc-2310	7	14	creative	creative	ADJ
dpc-2310	7	15	commons	common	NOUN
dpc-2310	7	16	attribution	attribution	NOUN
dpc-2310	7	17	-	-	PUNCT
dpc-2310	7	18	noncommercial	noncommercial	ADJ
dpc-2310	7	19	license	license	NOUN
dpc-2310	7	20	(	(	PUNCT
dpc-2310	7	21	by	by	ADP
dpc-2310	7	22	-	-	PUNCT
dpc-2310	7	23	nc-4.0	nc-4.0	NOUN
dpc-2310	7	24	)	)	PUNCT
dpc-2310	7	25	,	,	PUNCT
dpc-2310	7	26	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-2310	7	27	,	,	PUNCT
dpc-2310	7	28	which	which	PRON
dpc-2310	7	29	permits	permit	VERB
dpc-2310	7	30	unrestricted	unrestricted	ADJ
dpc-2310	7	31	noncommercial	noncommercial	ADJ
dpc-2310	7	32	use	use	NOUN
dpc-2310	7	33	,	,	PUNCT
dpc-2310	7	34	distribution	distribution	NOUN
dpc-2310	7	35	,	,	PUNCT
dpc-2310	7	36	and	and	CCONJ
dpc-2310	7	37	reproduction	reproduction	NOUN
dpc-2310	7	38	in	in	ADP
dpc-2310	7	39	any	any	DET
dpc-2310	7	40	medium	medium	NOUN
dpc-2310	7	41	,	,	PUNCT
dpc-2310	7	42	provided	provide	VERB
dpc-2310	7	43	the	the	DET
dpc-2310	7	44	original	original	ADJ
dpc-2310	7	45	authors	author	NOUN
dpc-2310	7	46	and	and	CCONJ
dpc-2310	7	47	source	source	NOUN
dpc-2310	7	48	are	be	AUX
dpc-2310	7	49	credited	credit	VERB
dpc-2310	7	50	.	.	PUNCT
dpc-2310	8	1	funding	funding	NOUN
dpc-2310	8	2	:	:	PUNCT
dpc-2310	8	3	none	none	NOUN
dpc-2310	8	4	.	.	PUNCT
dpc-2310	9	1	competing	compete	VERB
dpc-2310	9	2	interests	interest	NOUN
dpc-2310	9	3	:	:	PUNCT
dpc-2310	9	4	none	none	NOUN
dpc-2310	9	5	.	.	PUNCT
dpc-2310	10	1	authorship	authorship	NOUN
dpc-2310	10	2	:	:	PUNCT
dpc-2310	10	3	all	all	DET
dpc-2310	10	4	authors	author	NOUN
dpc-2310	10	5	have	have	AUX
dpc-2310	10	6	contributed	contribute	VERB
dpc-2310	10	7	significantly	significantly	ADV
dpc-2310	10	8	to	to	ADP
dpc-2310	10	9	this	this	DET
dpc-2310	10	10	publication	publication	NOUN
dpc-2310	10	11	.	.	PUNCT
dpc-2310	11	1	corresponding	correspond	VERB
dpc-2310	11	2	author	author	NOUN
dpc-2310	11	3	:	:	PUNCT
dpc-2310	11	4	giulia	giulia	PROPN
dpc-2310	11	5	calabrese	calabrese	PROPN
dpc-2310	11	6	,	,	PUNCT
dpc-2310	11	7	md	md	PROPN
dpc-2310	11	8	,	,	PUNCT
dpc-2310	11	9	dermatology	dermatology	NOUN
dpc-2310	11	10	unit	unit	NOUN
dpc-2310	11	11	,	,	PUNCT
dpc-2310	11	12	department	department	NOUN
dpc-2310	11	13	of	of	ADP
dpc-2310	11	14	mental	mental	ADJ
dpc-2310	11	15	and	and	CCONJ
dpc-2310	11	16	physical	physical	ADJ
dpc-2310	11	17	health	health	NOUN
dpc-2310	11	18	and	and	CCONJ
dpc-2310	11	19	preventive	preventive	ADJ
dpc-2310	11	20	medicine	medicine	NOUN
dpc-2310	11	21	,	,	PUNCT
dpc-2310	11	22	university	university	PROPN
dpc-2310	11	23	of	of	ADP
dpc-2310	11	24	campania	campania	PROPN
dpc-2310	11	25	luigi	luigi	PROPN
dpc-2310	11	26	vanvitelli	vanvitelli	PROPN
dpc-2310	11	27	,	,	PUNCT
dpc-2310	11	28	e	e	NOUN
dpc-2310	11	29	-	-	NOUN
dpc-2310	11	30	mail	mail	NOUN
dpc-2310	11	31	:	:	PUNCT
dpc-2310	11	32	allergologiavanvitel-li@gmail.com	allergologiavanvitel-li@gmail.com	X
dpc-2310	11	33	this	this	DET
dpc-2310	11	34	article	article	NOUN
dpc-2310	11	35	is	be	AUX
dpc-2310	11	36	part	part	NOUN
dpc-2310	11	37	of	of	ADP
dpc-2310	11	38	a	a	DET
dpc-2310	11	39	series	series	NOUN
dpc-2310	11	40	of	of	ADP
dpc-2310	11	41	reviews	review	NOUN
dpc-2310	11	42	dedicated	dedicate	VERB
dpc-2310	11	43	to	to	ADP
dpc-2310	11	44	atopic	atopic	NOUN
dpc-2310	11	45	dermatitis	dermatitis	NOUN
dpc-2310	11	46	,	,	PUNCT
dpc-2310	11	47	guest	guest	NOUN
dpc-2310	11	48	edited	edit	VERB
dpc-2310	11	49	by	by	ADP
dpc-2310	11	50	prof	prof	PROPN
dpc-2310	11	51	anna	anna	PROPN
dpc-2310	11	52	balato	balato	PROPN
dpc-2310	11	53	.	.	PUNCT
dpc-2310	12	1	guest	guest	PROPN
dpc-2310	12	2	editor	editor	PROPN
dpc-2310	12	3	prof	prof	PROPN
dpc-2310	12	4	.	.	PROPN
dpc-2310	13	1	anna	anna	PROPN
dpc-2310	13	2	balato	balato	PROPN
dpc-2310	13	3	,	,	PUNCT
dpc-2310	13	4	md	md	PROPN
dpc-2310	13	5	,	,	PUNCT
dpc-2310	13	6	phd	phd	NOUN
dpc-2310	13	7	associate	associate	NOUN
dpc-2310	13	8	professor	professor	NOUN
dpc-2310	13	9	of	of	ADP
dpc-2310	13	10	dermatology	dermatology	NOUN
dpc-2310	13	11	,	,	PUNCT
dpc-2310	13	12	dermatology	dermatology	NOUN
dpc-2310	13	13	unit	unit	NOUN
dpc-2310	13	14	,	,	PUNCT
dpc-2310	13	15	university	university	PROPN
dpc-2310	13	16	of	of	ADP
dpc-2310	13	17	campania	campania	PROPN
dpc-2310	13	18	,	,	PUNCT
dpc-2310	13	19	naples	naples	PROPN
dpc-2310	13	20	,	,	PUNCT
dpc-2310	13	21	italy	italy	PROPN
dpc-2310	13	22	atopic	atopic	PROPN
dpc-2310	13	23	dermatitis	dermatitis	PROPN
dpc-2310	13	24	is	be	AUX
dpc-2310	13	25	a	a	DET
dpc-2310	13	26	th2	th2	PROPN
dpc-2310	13	27	disease	disease	NOUN
dpc-2310	13	28	,	,	PUNCT
dpc-2310	13	29	due	due	ADP
dpc-2310	13	30	to	to	PART
dpc-2310	13	31	relapse	relapse	VERB
dpc-2310	13	32	of	of	ADP
dpc-2310	13	33	il-4	il-4	NOUN
dpc-2310	13	34	and	and	CCONJ
dpc-2310	13	35	il-13	il-13	ADP
dpc-2310	13	36	by	by	ADP
dpc-2310	13	37	th2	th2	PROPN
dpc-2310	13	38	cells	cell	NOUN
dpc-2310	13	39	.	.	PUNCT
dpc-2310	14	1	despite	despite	SCONJ
dpc-2310	14	2	the	the	DET
dpc-2310	14	3	approval	approval	NOUN
dpc-2310	14	4	by	by	ADP
dpc-2310	14	5	fda	fda	PROPN
dpc-2310	14	6	of	of	ADP
dpc-2310	14	7	dupilumab	dupilumab	NOUN
dpc-2310	14	8	,	,	PUNCT
dpc-2310	14	9	the	the	DET
dpc-2310	14	10	first	first	ADJ
dpc-2310	14	11	monoclonal	monoclonal	NOUN
dpc-2310	14	12	antibody	antibody	NOUN
dpc-2310	14	13	for	for	ADP
dpc-2310	14	14	the	the	DET
dpc-2310	14	15	severe	severe	ADJ
dpc-2310	14	16	forms	form	NOUN
dpc-2310	14	17	,	,	PUNCT
dpc-2310	14	18	traditional	traditional	ADJ
dpc-2310	14	19	drugs	drug	NOUN
dpc-2310	14	20	remain	remain	VERB
dpc-2310	14	21	a	a	DET
dpc-2310	14	22	milestone	milestone	NOUN
dpc-2310	14	23	for	for	ADP
dpc-2310	14	24	the	the	DET
dpc-2310	14	25	treatment	treatment	NOUN
dpc-2310	14	26	of	of	ADP
dpc-2310	14	27	this	this	DET
dpc-2310	14	28	dermatosis	dermatosis	NOUN
dpc-2310	14	29	.	.	PUNCT
dpc-2310	15	1	dermatologists	dermatologist	NOUN
dpc-2310	15	2	need	need	VERB
dpc-2310	15	3	a	a	DET
dpc-2310	15	4	good	good	ADJ
dpc-2310	15	5	knowledge	knowledge	NOUN
dpc-2310	15	6	of	of	ADP
dpc-2310	15	7	all	all	DET
dpc-2310	15	8	therapies	therapy	NOUN
dpc-2310	15	9	for	for	ADP
dpc-2310	15	10	an	an	DET
dpc-2310	15	11	integrated	integrate	VERB
dpc-2310	15	12	and	and	CCONJ
dpc-2310	15	13	personalized	personalized	ADJ
dpc-2310	15	14	management	management	NOUN
dpc-2310	15	15	of	of	ADP
dpc-2310	15	16	patients	patient	NOUN
dpc-2310	15	17	.	.	PUNCT
dpc-2310	16	1	abstract	abstract	ADJ
dpc-2310	16	2	introduction	introduction	NOUN
dpc-2310	16	3	atopic	atopic	NOUN
dpc-2310	16	4	dermatitis	dermatitis	NOUN
dpc-2310	16	5	(	(	PUNCT
dpc-2310	16	6	ad	ad	NOUN
dpc-2310	16	7	)	)	PUNCT
dpc-2310	16	8	is	be	AUX
dpc-2310	16	9	a	a	DET
dpc-2310	16	10	chronic	chronic	NOUN
dpc-2310	16	11	,	,	PUNCT
dpc-2310	16	12	inflammatory	inflammatory	ADJ
dpc-2310	16	13	skin	skin	NOUN
dpc-2310	16	14	disease	disease	NOUN
dpc-2310	16	15	,	,	PUNCT
dpc-2310	16	16	characterized	characterize	VERB
dpc-2310	16	17	by	by	ADP
dpc-2310	16	18	a	a	DET
dpc-2310	16	19	multifactorial	multifactorial	ADJ
dpc-2310	16	20	pathogenesis	pathogenesis	NOUN
dpc-2310	16	21	.	.	PUNCT
dpc-2310	17	1	ad	ad	NOUN
dpc-2310	17	2	is	be	AUX
dpc-2310	17	3	considered	consider	VERB
dpc-2310	17	4	a	a	DET
dpc-2310	17	5	prototypical	prototypical	ADJ
dpc-2310	17	6	th2	th2	PROPN
dpc-2310	17	7	disease	disease	NOUN
dpc-2310	17	8	,	,	PUNCT
dpc-2310	17	9	due	due	ADP
dpc-2310	17	10	to	to	PART
dpc-2310	17	11	relapse	relapse	VERB
dpc-2310	17	12	of	of	ADP
dpc-2310	17	13	il-4	il-4	NOUN
dpc-2310	17	14	and	and	CCONJ
dpc-2310	17	15	il-13	il-13	ADP
dpc-2310	17	16	by	by	ADP
dpc-2310	17	17	th2	th2	PROPN
dpc-2310	17	18	cells	cell	NOUN
dpc-2310	17	19	.	.	PUNCT
dpc-2310	18	1	il-4	il-4	PART
dpc-2310	19	1	and	and	CCONJ
dpc-2310	19	2	il-13	il-13	CCONJ
dpc-2310	19	3	are	be	AUX
dpc-2310	19	4	involved	involve	VERB
dpc-2310	19	5	in	in	ADP
dpc-2310	19	6	the	the	DET
dpc-2310	19	7	survival	survival	NOUN
dpc-2310	19	8	of	of	ADP
dpc-2310	19	9	th2	th2	PROPN
dpc-2310	19	10	cells	cell	NOUN
dpc-2310	19	11	,	,	PUNCT
dpc-2310	19	12	differentiation	differentiation	NOUN
dpc-2310	19	13	and	and	CCONJ
dpc-2310	19	14	activation	activation	NOUN
dpc-2310	19	15	of	of	ADP
dpc-2310	19	16	myeloid	myeloid	NOUN
dpc-2310	19	17	and	and	CCONJ
dpc-2310	19	18	dendritic	dendritic	ADJ
dpc-2310	19	19	cell	cell	NOUN
dpc-2310	19	20	,	,	PUNCT
dpc-2310	19	21	b	b	X
dpc-2310	19	22	-	-	PUNCT
dpc-2310	19	23	cell	cell	NOUN
dpc-2310	19	24	maturation	maturation	NOUN
dpc-2310	19	25	,	,	PUNCT
dpc-2310	19	26	stimulation	stimulation	NOUN
dpc-2310	19	27	of	of	ADP
dpc-2310	19	28	ige	ige	PROPN
dpc-2310	19	29	class	class	PROPN
dpc-2310	19	30	switching	switching	NOUN
dpc-2310	19	31	,	,	PUNCT
dpc-2310	19	32	eosinophil	eosinophil	ADJ
dpc-2310	19	33	chemotaxis	chemotaxis	ADJ
dpc-2310	19	34	and	and	CCONJ
dpc-2310	19	35	down	down	ADP
dpc-2310	19	36	-	-	PUNCT
dpc-2310	19	37	regulation	regulation	NOUN
dpc-2310	19	38	of	of	ADP
dpc-2310	19	39	genes	gene	NOUN
dpc-2310	19	40	involved	involve	VERB
dpc-2310	19	41	in	in	ADP
dpc-2310	19	42	skin	skin	NOUN
dpc-2310	19	43	barrier	barrier	NOUN
dpc-2310	19	44	function	function	NOUN
dpc-2310	19	45	(	(	PUNCT
dpc-2310	19	46	fillagrin	fillagrin	ADJ
dpc-2310	19	47	,	,	PUNCT
dpc-2310	19	48	locrin	locrin	NOUN
dpc-2310	19	49	,	,	PUNCT
dpc-2310	19	50	and	and	CCONJ
dpc-2310	19	51	involucrin	involucrin	ADJ
dpc-2310	19	52	)	)	PUNCT
dpc-2310	19	53	.	.	PUNCT
dpc-2310	20	1	2	2	NUM
dpc-2310	20	2	review	review	NOUN
dpc-2310	20	3	|	|	ADV
dpc-2310	20	4	dermatol	dermatol	ADJ
dpc-2310	20	5	pract	pract	NOUN
dpc-2310	20	6	concept	concept	NOUN
dpc-2310	20	7	.	.	PUNCT
dpc-2310	21	1	2022;12(1):e2022155	2022;12(1):e2022155	NUM
dpc-2310	21	2	conventional	conventional	ADJ
dpc-2310	21	3	treatments	treatment	NOUN
dpc-2310	21	4	represent	represent	VERB
dpc-2310	21	5	a	a	DET
dpc-2310	21	6	cornerstone	cornerstone	NOUN
dpc-2310	21	7	of	of	ADP
dpc-2310	21	8	ad	ad	NOUN
dpc-2310	21	9	therapy	therapy	NOUN
dpc-2310	21	10	and	and	CCONJ
dpc-2310	21	11	are	be	AUX
dpc-2310	21	12	the	the	DET
dpc-2310	21	13	first	first	ADJ
dpc-2310	21	14	-	-	PUNCT
dpc-2310	21	15	line	line	NOUN
dpc-2310	21	16	therapy	therapy	NOUN
dpc-2310	21	17	for	for	ADP
dpc-2310	21	18	the	the	DET
dpc-2310	21	19	mild	mild	ADJ
dpc-2310	21	20	-	-	PUNCT
dpc-2310	21	21	moderate	moderate	ADJ
dpc-2310	21	22	forms	form	NOUN
dpc-2310	21	23	.	.	PUNCT
dpc-2310	22	1	with	with	ADP
dpc-2310	22	2	biological	biological	ADJ
dpc-2310	22	3	drugs	drug	NOUN
dpc-2310	22	4	rapidly	rapidly	ADV
dpc-2310	22	5	emerging	emerge	VERB
dpc-2310	22	6	,	,	PUNCT
dpc-2310	22	7	it	it	PRON
dpc-2310	22	8	is	be	AUX
dpc-2310	22	9	important	important	ADJ
dpc-2310	22	10	for	for	ADP
dpc-2310	22	11	clinicians	clinician	NOUN
dpc-2310	22	12	to	to	PART
dpc-2310	22	13	combine	combine	VERB
dpc-2310	22	14	the	the	DET
dpc-2310	22	15	new	new	ADJ
dpc-2310	22	16	treatments	treatment	NOUN
dpc-2310	22	17	with	with	ADP
dpc-2310	22	18	the	the	DET
dpc-2310	22	19	traditional	traditional	ADJ
dpc-2310	22	20	ones	one	NOUN
dpc-2310	22	21	to	to	PART
dpc-2310	22	22	improve	improve	VERB
dpc-2310	22	23	the	the	DET
dpc-2310	22	24	response	response	NOUN
dpc-2310	22	25	of	of	ADP
dpc-2310	22	26	the	the	DET
dpc-2310	22	27	patients	patient	NOUN
dpc-2310	22	28	[	[	X
dpc-2310	22	29	1	1	NUM
dpc-2310	22	30	-	-	SYM
dpc-2310	22	31	4,17	4,17	NUM
dpc-2310	22	32	]	]	PUNCT
dpc-2310	22	33	.	.	PUNCT
dpc-2310	23	1	conventional	conventional	ADJ
dpc-2310	23	2	therapy	therapy	NOUN
dpc-2310	23	3	for	for	ADP
dpc-2310	23	4	ad	ad	NOUN
dpc-2310	23	5	conventional	conventional	ADJ
dpc-2310	23	6	treatments	treatment	NOUN
dpc-2310	23	7	for	for	ADP
dpc-2310	23	8	ad	ad	NOUN
dpc-2310	23	9	can	can	AUX
dpc-2310	23	10	be	be	AUX
dpc-2310	23	11	differentiated	differentiate	VERB
dpc-2310	23	12	in	in	ADP
dpc-2310	23	13	topical	topical	ADJ
dpc-2310	23	14	and	and	CCONJ
dpc-2310	23	15	systemic	systemic	ADJ
dpc-2310	23	16	.	.	PUNCT
dpc-2310	24	1	topical	topical	ADJ
dpc-2310	24	2	agents	agent	NOUN
dpc-2310	24	3	are	be	AUX
dpc-2310	24	4	moisturizers	moisturizer	NOUN
dpc-2310	24	5	,	,	PUNCT
dpc-2310	24	6	corticosteroids	corticosteroid	NOUN
dpc-2310	24	7	,	,	PUNCT
dpc-2310	24	8	calcineurin	calcineurin	ADJ
dpc-2310	24	9	inhibitors	inhibitor	NOUN
dpc-2310	24	10	and	and	CCONJ
dpc-2310	24	11	antimicrobials	antimicrobial	NOUN
dpc-2310	24	12	/	/	SYM
dpc-2310	24	13	antiseptics	antiseptic	NOUN
dpc-2310	24	14	,	,	PUNCT
dpc-2310	24	15	used	use	VERB
dpc-2310	24	16	in	in	ADP
dpc-2310	24	17	monotherapy	monotherapy	NOUN
dpc-2310	24	18	or	or	CCONJ
dpc-2310	24	19	in	in	ADP
dpc-2310	24	20	combination	combination	NOUN
dpc-2310	24	21	.	.	PUNCT
dpc-2310	25	1	in	in	ADP
dpc-2310	25	2	the	the	DET
dpc-2310	25	3	field	field	NOUN
dpc-2310	25	4	of	of	ADP
dpc-2310	25	5	topical	topical	ADJ
dpc-2310	25	6	therapies	therapy	NOUN
dpc-2310	25	7	,	,	PUNCT
dpc-2310	25	8	wet	wet	ADJ
dpc-2310	25	9	wrap	wrap	NOUN
dpc-2310	25	10	therapy	therapy	NOUN
dpc-2310	25	11	must	must	AUX
dpc-2310	25	12	also	also	ADV
dpc-2310	25	13	be	be	AUX
dpc-2310	25	14	mentioned	mention	VERB
dpc-2310	25	15	[	[	PUNCT
dpc-2310	25	16	5	5	NUM
dpc-2310	25	17	-	-	SYM
dpc-2310	25	18	9	9	NUM
dpc-2310	25	19	]	]	PUNCT
dpc-2310	25	20	.	.	PUNCT
dpc-2310	26	1	systemic	systemic	ADJ
dpc-2310	26	2	treatments	treatment	NOUN
dpc-2310	26	3	,	,	PUNCT
dpc-2310	26	4	used	use	VERB
dpc-2310	26	5	for	for	ADP
dpc-2310	26	6	severe	severe	ADJ
dpc-2310	26	7	and	and	CCONJ
dpc-2310	26	8	recalcitrant	recalcitrant	ADJ
dpc-2310	26	9	forms	form	NOUN
dpc-2310	26	10	,	,	PUNCT
dpc-2310	26	11	consist	consist	VERB
dpc-2310	26	12	in	in	ADP
dpc-2310	26	13	phototherapy	phototherapy	NOUN
dpc-2310	26	14	,	,	PUNCT
dpc-2310	26	15	systemic	systemic	ADJ
dpc-2310	26	16	corticosteroids	corticosteroid	NOUN
dpc-2310	26	17	,	,	PUNCT
dpc-2310	26	18	cyclosporine	cyclosporine	NOUN
dpc-2310	26	19	,	,	PUNCT
dpc-2310	26	20	methotrexate	methotrexate	NOUN
dpc-2310	26	21	,	,	PUNCT
dpc-2310	26	22	mycophenylate	mycophenylate	NOUN
dpc-2310	26	23	mofetil	mofetil	NOUN
dpc-2310	26	24	and	and	CCONJ
dpc-2310	26	25	azathioprine	azathioprine	NOUN
dpc-2310	27	1	[	[	X
dpc-2310	27	2	10	10	NUM
dpc-2310	27	3	]	]	PUNCT
dpc-2310	27	4	.	.	PUNCT
dpc-2310	28	1	moisturizers	moisturizer	NOUN
dpc-2310	28	2	moisturizers	moisturizer	NOUN
dpc-2310	28	3	are	be	AUX
dpc-2310	28	4	used	use	VERB
dpc-2310	28	5	to	to	PART
dpc-2310	28	6	combat	combat	VERB
dpc-2310	28	7	xerosis	xerosis	NOUN
dpc-2310	28	8	(	(	PUNCT
dpc-2310	28	9	one	one	NUM
dpc-2310	28	10	of	of	ADP
dpc-2310	28	11	the	the	DET
dpc-2310	28	12	cardinal	cardinal	ADJ
dpc-2310	28	13	clinical	clinical	ADJ
dpc-2310	28	14	features	feature	NOUN
dpc-2310	28	15	of	of	ADP
dpc-2310	28	16	ad	ad	NOUN
dpc-2310	28	17	and	and	CCONJ
dpc-2310	28	18	the	the	DET
dpc-2310	28	19	result	result	NOUN
dpc-2310	28	20	of	of	ADP
dpc-2310	28	21	a	a	DET
dpc-2310	28	22	dysfunctional	dysfunctional	ADJ
dpc-2310	28	23	epidermal	epidermal	ADJ
dpc-2310	28	24	barrier	barrier	NOUN
dpc-2310	28	25	)	)	PUNCT
dpc-2310	28	26	and	and	CCONJ
dpc-2310	28	27	transepidermal	transepidermal	ADJ
dpc-2310	28	28	water	water	NOUN
dpc-2310	28	29	loss	loss	NOUN
dpc-2310	28	30	.	.	PUNCT
dpc-2310	29	1	they	they	PRON
dpc-2310	29	2	reduce	reduce	VERB
dpc-2310	29	3	disease	disease	NOUN
dpc-2310	29	4	severity	severity	NOUN
dpc-2310	29	5	,	,	PUNCT
dpc-2310	29	6	the	the	DET
dpc-2310	29	7	need	need	NOUN
dpc-2310	29	8	for	for	ADP
dpc-2310	29	9	pharmacologic	pharmacologic	ADJ
dpc-2310	29	10	intervention	intervention	NOUN
dpc-2310	29	11	and	and	CCONJ
dpc-2310	29	12	should	should	AUX
dpc-2310	29	13	be	be	AUX
dpc-2310	29	14	applied	apply	VERB
dpc-2310	29	15	soon	soon	ADV
dpc-2310	29	16	after	after	ADP
dpc-2310	29	17	bathing	bathe	VERB
dpc-2310	29	18	,	,	PUNCT
dpc-2310	29	19	almost	almost	ADV
dpc-2310	29	20	once	once	ADV
dpc-2310	29	21	a	a	DET
dpc-2310	29	22	day	day	NOUN
dpc-2310	29	23	[	[	X
dpc-2310	29	24	5	5	NUM
dpc-2310	29	25	-	-	SYM
dpc-2310	29	26	7	7	NUM
dpc-2310	29	27	]	]	PUNCT
dpc-2310	29	28	.	.	PUNCT
dpc-2310	30	1	moisturizers	moisturizer	NOUN
dpc-2310	30	2	can	can	AUX
dpc-2310	30	3	be	be	AUX
dpc-2310	30	4	classified	classify	VERB
dpc-2310	30	5	in	in	ADP
dpc-2310	30	6	traditional	traditional	ADJ
dpc-2310	30	7	(	(	PUNCT
dpc-2310	30	8	glycol	glycol	NOUN
dpc-2310	30	9	and	and	CCONJ
dpc-2310	30	10	glyceryl	glyceryl	NOUN
dpc-2310	30	11	stearate	stearate	NOUN
dpc-2310	30	12	,	,	PUNCT
dpc-2310	30	13	soy	soy	NOUN
dpc-2310	30	14	sterols	sterol	NOUN
dpc-2310	30	15	,	,	PUNCT
dpc-2310	30	16	petrolatum	petrolatum	NOUN
dpc-2310	30	17	,	,	PUNCT
dpc-2310	30	18	dimethicone	dimethicone	NOUN
dpc-2310	30	19	,	,	PUNCT
dpc-2310	30	20	mineral	mineral	NOUN
dpc-2310	30	21	oil	oil	NOUN
dpc-2310	30	22	,	,	PUNCT
dpc-2310	30	23	glycerol	glycerol	NOUN
dpc-2310	30	24	,	,	PUNCT
dpc-2310	30	25	lactic	lactic	ADJ
dpc-2310	30	26	acid	acid	NOUN
dpc-2310	30	27	,	,	PUNCT
dpc-2310	30	28	urea	urea	NOUN
dpc-2310	30	29	)	)	PUNCT
dpc-2310	30	30	and	and	CCONJ
dpc-2310	30	31	prescription	prescription	NOUN
dpc-2310	30	32	emollient	emollient	NOUN
dpc-2310	30	33	devices	device	NOUN
dpc-2310	30	34	(	(	PUNCT
dpc-2310	30	35	peds	ped	NOUN
dpc-2310	30	36	)	)	PUNCT
dpc-2310	30	37	.	.	PUNCT
dpc-2310	31	1	traditional	traditional	ADJ
dpc-2310	31	2	agents	agent	NOUN
dpc-2310	31	3	contain	contain	VERB
dpc-2310	31	4	varying	vary	VERB
dpc-2310	31	5	amounts	amount	NOUN
dpc-2310	31	6	of	of	ADP
dpc-2310	31	7	emollient	emollient	NOUN
dpc-2310	31	8	,	,	PUNCT
dpc-2310	31	9	occlusive	occlusive	ADJ
dpc-2310	31	10	and	and	CCONJ
dpc-2310	31	11	humectant	humectant	ADJ
dpc-2310	31	12	ingredients	ingredient	NOUN
dpc-2310	31	13	.	.	PUNCT
dpc-2310	32	1	emollients	emollient	NOUN
dpc-2310	32	2	(	(	PUNCT
dpc-2310	32	3	eg	eg	NOUN
dpc-2310	32	4	glycol	glycol	NOUN
dpc-2310	32	5	and	and	CCONJ
dpc-2310	32	6	glyceryl	glyceryl	NOUN
dpc-2310	32	7	stearate	stearate	NOUN
dpc-2310	32	8	,	,	PUNCT
dpc-2310	32	9	soy	soy	NOUN
dpc-2310	32	10	sterols	sterol	NOUN
dpc-2310	32	11	)	)	PUNCT
dpc-2310	32	12	lubricate	lubricate	VERB
dpc-2310	32	13	and	and	CCONJ
dpc-2310	32	14	soften	soften	VERB
dpc-2310	32	15	the	the	DET
dpc-2310	32	16	skin	skin	NOUN
dpc-2310	32	17	,	,	PUNCT
dpc-2310	32	18	occlusive	occlusive	ADJ
dpc-2310	32	19	agents	agent	NOUN
dpc-2310	32	20	(	(	PUNCT
dpc-2310	32	21	eg	eg	NOUN
dpc-2310	32	22	petrolatum	petrolatum	NOUN
dpc-2310	32	23	,	,	PUNCT
dpc-2310	32	24	dimethicone	dimethicone	NOUN
dpc-2310	32	25	,	,	PUNCT
dpc-2310	32	26	mineral	mineral	NOUN
dpc-2310	32	27	oil	oil	NOUN
dpc-2310	32	28	)	)	PUNCT
dpc-2310	32	29	form	form	VERB
dpc-2310	32	30	a	a	DET
dpc-2310	32	31	layer	layer	NOUN
dpc-2310	32	32	to	to	PART
dpc-2310	32	33	reduce	reduce	VERB
dpc-2310	32	34	evaporation	evaporation	NOUN
dpc-2310	32	35	of	of	ADP
dpc-2310	32	36	water	water	NOUN
dpc-2310	32	37	,	,	PUNCT
dpc-2310	32	38	while	while	SCONJ
dpc-2310	32	39	humectants	humectant	NOUN
dpc-2310	32	40	(	(	PUNCT
dpc-2310	32	41	.g	.g	NOUN
dpc-2310	32	42	glycerol	glycerol	NOUN
dpc-2310	32	43	,	,	PUNCT
dpc-2310	32	44	lactic	lactic	ADJ
dpc-2310	32	45	acid	acid	NOUN
dpc-2310	32	46	,	,	PUNCT
dpc-2310	32	47	urea	urea	NOUN
dpc-2310	32	48	)	)	PUNCT
dpc-2310	32	49	attract	attract	VERB
dpc-2310	32	50	and	and	CCONJ
dpc-2310	32	51	hold	hold	VERB
dpc-2310	32	52	water	water	NOUN
dpc-2310	32	53	.	.	PUNCT
dpc-2310	33	1	several	several	ADJ
dpc-2310	33	2	clinical	clinical	ADJ
dpc-2310	33	3	trials	trial	NOUN
dpc-2310	33	4	have	have	AUX
dpc-2310	33	5	shown	show	VERB
dpc-2310	33	6	that	that	SCONJ
dpc-2310	33	7	they	they	PRON
dpc-2310	33	8	lessen	lessen	VERB
dpc-2310	33	9	symptoms	symptom	NOUN
dpc-2310	33	10	and	and	CCONJ
dpc-2310	33	11	signs	sign	NOUN
dpc-2310	33	12	of	of	ADP
dpc-2310	33	13	ad	ad	NOUN
dpc-2310	33	14	,	,	PUNCT
dpc-2310	33	15	including	include	VERB
dpc-2310	33	16	pruritus	pruritus	PROPN
dpc-2310	33	17	,	,	PUNCT
dpc-2310	33	18	erythema	erythema	ADV
dpc-2310	33	19	,	,	PUNCT
dpc-2310	33	20	fissuring	fissuring	NOUN
dpc-2310	33	21	,	,	PUNCT
dpc-2310	33	22	and	and	CCONJ
dpc-2310	33	23	lichenification	lichenification	NOUN
dpc-2310	34	1	[	[	X
dpc-2310	34	2	5	5	NUM
dpc-2310	34	3	-	-	SYM
dpc-2310	34	4	7	7	NUM
dpc-2310	34	5	]	]	PUNCT
dpc-2310	34	6	.	.	PUNCT
dpc-2310	35	1	the	the	DET
dpc-2310	35	2	term	term	NOUN
dpc-2310	35	3	ped	ped	NOUN
dpc-2310	35	4	has	have	AUX
dpc-2310	35	5	been	be	AUX
dpc-2310	35	6	introduced	introduce	VERB
dpc-2310	35	7	to	to	PART
dpc-2310	35	8	identify	identify	VERB
dpc-2310	35	9	a	a	DET
dpc-2310	35	10	new	new	ADJ
dpc-2310	35	11	class	class	NOUN
dpc-2310	35	12	of	of	ADP
dpc-2310	35	13	topical	topical	ADJ
dpc-2310	35	14	agents	agent	NOUN
dpc-2310	35	15	designed	design	VERB
dpc-2310	35	16	to	to	PART
dpc-2310	35	17	target	target	VERB
dpc-2310	35	18	the	the	DET
dpc-2310	35	19	specific	specific	ADJ
dpc-2310	35	20	defects	defect	NOUN
dpc-2310	35	21	in	in	ADP
dpc-2310	35	22	skin	skin	NOUN
dpc-2310	35	23	barrier	barrier	NOUN
dpc-2310	35	24	function	function	NOUN
dpc-2310	35	25	observed	observe	VERB
dpc-2310	35	26	in	in	ADP
dpc-2310	35	27	ad	ad	NOUN
dpc-2310	35	28	.	.	PUNCT
dpc-2310	36	1	they	they	PRON
dpc-2310	36	2	include	include	VERB
dpc-2310	36	3	preparations	preparation	NOUN
dpc-2310	36	4	having	have	VERB
dpc-2310	36	5	distinct	distinct	ADJ
dpc-2310	36	6	ratios	ratio	NOUN
dpc-2310	36	7	of	of	ADP
dpc-2310	36	8	lipids	lipid	NOUN
dpc-2310	36	9	that	that	DET
dpc-2310	36	10	mimic	mimic	ADJ
dpc-2310	36	11	endogenous	endogenous	ADJ
dpc-2310	36	12	compositions	composition	NOUN
dpc-2310	36	13	and	and	CCONJ
dpc-2310	36	14	containing	contain	VERB
dpc-2310	36	15	palmitoylethanolamide	palmitoylethanolamide	NOUN
dpc-2310	36	16	,	,	PUNCT
dpc-2310	36	17	glycyrrhetinic	glycyrrhetinic	ADJ
dpc-2310	36	18	acid	acid	NOUN
dpc-2310	36	19	,	,	PUNCT
dpc-2310	36	20	or	or	CCONJ
dpc-2310	36	21	other	other	ADJ
dpc-2310	36	22	hydrolipids	hydrolipid	NOUN
dpc-2310	36	23	.	.	PUNCT
dpc-2310	37	1	peds	ped	NOUN
dpc-2310	37	2	may	may	AUX
dpc-2310	37	3	contain	contain	VERB
dpc-2310	37	4	an	an	DET
dpc-2310	37	5	antioxidant	antioxidant	ADJ
dpc-2310	37	6	agent	agent	NOUN
dpc-2310	37	7	,	,	PUNCT
dpc-2310	37	8	such	such	ADJ
dpc-2310	37	9	as	as	ADP
dpc-2310	37	10	furfuryl	furfuryl	NOUN
dpc-2310	37	11	palmitate	palmitate	NOUN
dpc-2310	37	12	or	or	CCONJ
dpc-2310	37	13	furfuryl	furfuryl	NOUN
dpc-2310	37	14	derivatives	derivative	NOUN
dpc-2310	37	15	.	.	PUNCT
dpc-2310	38	1	peds	ped	NOUN
dpc-2310	38	2	lessen	lessen	VERB
dpc-2310	38	3	xerosis	xerosis	NOUN
dpc-2310	38	4	and	and	CCONJ
dpc-2310	38	5	inflammation	inflammation	NOUN
dpc-2310	38	6	but	but	CCONJ
dpc-2310	38	7	they	they	PRON
dpc-2310	38	8	have	have	AUX
dpc-2310	38	9	been	be	AUX
dpc-2310	38	10	tested	test	VERB
dpc-2310	38	11	in	in	ADP
dpc-2310	38	12	a	a	DET
dpc-2310	38	13	small	small	ADJ
dpc-2310	38	14	number	number	NOUN
dpc-2310	38	15	of	of	ADP
dpc-2310	38	16	controlled	control	VERB
dpc-2310	38	17	studies	study	NOUN
dpc-2310	38	18	[	[	X
dpc-2310	38	19	11	11	NUM
dpc-2310	38	20	]	]	PUNCT
dpc-2310	38	21	.	.	PUNCT
dpc-2310	39	1	moisturizers	moisturizer	NOUN
dpc-2310	39	2	are	be	AUX
dpc-2310	39	3	the	the	DET
dpc-2310	39	4	main	main	ADJ
dpc-2310	39	5	primary	primary	ADJ
dpc-2310	39	6	treatment	treatment	NOUN
dpc-2310	39	7	for	for	ADP
dpc-2310	39	8	mild	mild	ADJ
dpc-2310	39	9	forms	form	NOUN
dpc-2310	39	10	and	and	CCONJ
dpc-2310	39	11	should	should	AUX
dpc-2310	39	12	be	be	AUX
dpc-2310	39	13	part	part	NOUN
dpc-2310	39	14	of	of	ADP
dpc-2310	39	15	the	the	DET
dpc-2310	39	16	regimen	regiman	NOUN
dpc-2310	39	17	for	for	ADP
dpc-2310	39	18	moderate	moderate	ADJ
dpc-2310	39	19	and	and	CCONJ
dpc-2310	39	20	severe	severe	ADJ
dpc-2310	39	21	ones	one	NOUN
dpc-2310	39	22	because	because	SCONJ
dpc-2310	39	23	they	they	PRON
dpc-2310	39	24	reduce	reduce	VERB
dpc-2310	39	25	inflammation	inflammation	NOUN
dpc-2310	39	26	,	,	PUNCT
dpc-2310	39	27	the	the	DET
dpc-2310	39	28	prescription	prescription	NOUN
dpc-2310	39	29	of	of	ADP
dpc-2310	39	30	topical	topical	ADJ
dpc-2310	39	31	corticosteroids	corticosteroid	NOUN
dpc-2310	39	32	and	and	CCONJ
dpc-2310	39	33	prevent	prevent	VERB
dpc-2310	39	34	the	the	DET
dpc-2310	39	35	flares	flare	NOUN
dpc-2310	39	36	in	in	ADP
dpc-2310	39	37	the	the	DET
dpc-2310	39	38	maintenance	maintenance	NOUN
dpc-2310	39	39	treatment	treatment	NOUN
dpc-2310	39	40	.	.	PUNCT
dpc-2310	40	1	there	there	PRON
dpc-2310	40	2	are	be	VERB
dpc-2310	40	3	few	few	ADJ
dpc-2310	40	4	studies	study	NOUN
dpc-2310	40	5	that	that	PRON
dpc-2310	40	6	have	have	AUX
dpc-2310	40	7	compared	compare	VERB
dpc-2310	40	8	moisturizers	moisturizer	NOUN
dpc-2310	40	9	,	,	PUNCT
dpc-2310	40	10	but	but	CCONJ
dpc-2310	40	11	results	result	NOUN
dpc-2310	40	12	are	be	AUX
dpc-2310	40	13	overlapping	overlap	VERB
dpc-2310	40	14	.	.	PUNCT
dpc-2310	41	1	therefore	therefore	ADV
dpc-2310	41	2	,	,	PUNCT
dpc-2310	41	3	the	the	DET
dpc-2310	41	4	choice	choice	NOUN
dpc-2310	41	5	of	of	ADP
dpc-2310	41	6	moisturizing	moisturize	VERB
dpc-2310	41	7	agent	agent	NOUN
dpc-2310	41	8	is	be	AUX
dpc-2310	41	9	highly	highly	ADV
dpc-2310	41	10	dependent	dependent	ADJ
dpc-2310	41	11	on	on	ADP
dpc-2310	41	12	individual	individual	ADJ
dpc-2310	41	13	preference	preference	NOUN
dpc-2310	41	14	[	[	X
dpc-2310	41	15	5	5	NUM
dpc-2310	41	16	]	]	PUNCT
dpc-2310	41	17	.	.	PUNCT
dpc-2310	42	1	in	in	ADP
dpc-2310	42	2	ad	ad	NOUN
dpc-2310	42	3	,	,	PUNCT
dpc-2310	42	4	the	the	DET
dpc-2310	42	5	alteration	alteration	NOUN
dpc-2310	42	6	of	of	ADP
dpc-2310	42	7	skin	skin	NOUN
dpc-2310	42	8	barrier	barrier	NOUN
dpc-2310	42	9	is	be	AUX
dpc-2310	42	10	associated	associate	VERB
dpc-2310	42	11	with	with	ADP
dpc-2310	42	12	reduced	reduced	ADJ
dpc-2310	42	13	ceramide	ceramide	NOUN
dpc-2310	42	14	levels	level	NOUN
dpc-2310	42	15	,	,	PUNCT
dpc-2310	42	16	with	with	ADP
dpc-2310	42	17	a	a	DET
dpc-2310	42	18	consequential	consequential	ADJ
dpc-2310	42	19	increase	increase	NOUN
dpc-2310	42	20	in	in	ADP
dpc-2310	42	21	trans	trans	ADJ
dpc-2310	42	22	-	-	ADJ
dpc-2310	42	23	epidermal	epidermal	ADJ
dpc-2310	42	24	water	water	NOUN
dpc-2310	42	25	loss	loss	NOUN
dpc-2310	42	26	(	(	PUNCT
dpc-2310	42	27	tewl	tewl	NOUN
dpc-2310	42	28	)	)	PUNCT
dpc-2310	42	29	and	and	CCONJ
dpc-2310	42	30	reduction	reduction	NOUN
dpc-2310	42	31	in	in	ADP
dpc-2310	42	32	skin	skin	NOUN
dpc-2310	42	33	hydration	hydration	NOUN
dpc-2310	42	34	.	.	PUNCT
dpc-2310	43	1	it	it	PRON
dpc-2310	43	2	is	be	AUX
dpc-2310	43	3	not	not	PART
dpc-2310	43	4	yet	yet	ADV
dpc-2310	43	5	known	know	VERB
dpc-2310	43	6	whether	whether	SCONJ
dpc-2310	43	7	dupilumab	dupilumab	NOUN
dpc-2310	43	8	restores	restore	VERB
dpc-2310	43	9	skin	skin	NOUN
dpc-2310	43	10	barrier	barrier	NOUN
dpc-2310	43	11	function	function	NOUN
dpc-2310	43	12	.	.	PUNCT
dpc-2310	44	1	the	the	DET
dpc-2310	44	2	latter	latter	ADJ
dpc-2310	44	3	can	can	AUX
dpc-2310	44	4	be	be	AUX
dpc-2310	44	5	investigated	investigate	VERB
dpc-2310	44	6	using	use	VERB
dpc-2310	44	7	tewl	tewl	NOUN
dpc-2310	44	8	(	(	PUNCT
dpc-2310	44	9	that	that	PRON
dpc-2310	44	10	is	be	AUX
dpc-2310	44	11	the	the	DET
dpc-2310	44	12	water	water	NOUN
dpc-2310	44	13	evaporization	evaporization	NOUN
dpc-2310	44	14	rate	rate	NOUN
dpc-2310	44	15	in	in	ADP
dpc-2310	44	16	g	g	PROPN
dpc-2310	44	17	/	/	SYM
dpc-2310	44	18	h	h	NOUN
dpc-2310	44	19	/	/	SYM
dpc-2310	44	20	m2	m2	PROPN
dpc-2310	44	21	)	)	PUNCT
dpc-2310	44	22	and	and	CCONJ
dpc-2310	44	23	stratum	stratum	PROPN
dpc-2310	44	24	corneum	corneum	NOUN
dpc-2310	44	25	hydration	hydration	NOUN
dpc-2310	44	26	(	(	PUNCT
dpc-2310	44	27	sch	sch	INTJ
dpc-2310	44	28	)	)	PUNCT
dpc-2310	44	29	(	(	PUNCT
dpc-2310	44	30	the	the	DET
dpc-2310	44	31	water	water	NOUN
dpc-2310	44	32	content	content	NOUN
dpc-2310	44	33	in	in	ADP
dpc-2310	44	34	the	the	DET
dpc-2310	44	35	stratum	stratum	NOUN
dpc-2310	44	36	corneum	corneum	NOUN
dpc-2310	44	37	measured	measure	VERB
dpc-2310	44	38	by	by	ADP
dpc-2310	44	39	corneometer	corneometer	ADJ
dpc-2310	44	40	®	®	PROPN
dpc-2310	44	41	)	)	PUNCT
dpc-2310	44	42	.	.	PUNCT
dpc-2310	45	1	according	accord	VERB
dpc-2310	45	2	to	to	ADP
dpc-2310	45	3	a	a	DET
dpc-2310	45	4	recent	recent	ADJ
dpc-2310	45	5	study	study	NOUN
dpc-2310	45	6	,	,	PUNCT
dpc-2310	45	7	following	follow	VERB
dpc-2310	45	8	treatment	treatment	NOUN
dpc-2310	45	9	with	with	ADP
dpc-2310	45	10	dupilumab	dupilumab	NOUN
dpc-2310	45	11	,	,	PUNCT
dpc-2310	45	12	tewl	tewl	NOUN
dpc-2310	45	13	decreases	decrease	VERB
dpc-2310	45	14	quickly	quickly	ADV
dpc-2310	45	15	in	in	ADP
dpc-2310	45	16	the	the	DET
dpc-2310	45	17	skin	skin	NOUN
dpc-2310	45	18	interested	interested	ADJ
dpc-2310	45	19	by	by	ADP
dpc-2310	45	20	ad	ad	NOUN
dpc-2310	45	21	,	,	PUNCT
dpc-2310	45	22	while	while	SCONJ
dpc-2310	45	23	sch	sch	PROPN
dpc-2310	45	24	does	do	AUX
dpc-2310	45	25	not	not	PART
dpc-2310	45	26	improve	improve	VERB
dpc-2310	45	27	.	.	PUNCT
dpc-2310	46	1	because	because	SCONJ
dpc-2310	46	2	of	of	ADP
dpc-2310	46	3	the	the	DET
dpc-2310	46	4	small	small	ADJ
dpc-2310	46	5	sample	sample	NOUN
dpc-2310	46	6	size	size	NOUN
dpc-2310	46	7	in	in	ADP
dpc-2310	46	8	this	this	DET
dpc-2310	46	9	study	study	NOUN
dpc-2310	46	10	,	,	PUNCT
dpc-2310	46	11	further	further	ADJ
dpc-2310	46	12	papers	paper	NOUN
dpc-2310	46	13	are	be	AUX
dpc-2310	46	14	needed	need	VERB
dpc-2310	46	15	but	but	CCONJ
dpc-2310	46	16	it	it	PRON
dpc-2310	46	17	seems	seem	VERB
dpc-2310	46	18	that	that	SCONJ
dpc-2310	46	19	dupilumab	dupilumab	NOUN
dpc-2310	46	20	have	have	VERB
dpc-2310	46	21	no	no	DET
dpc-2310	46	22	effects	effect	NOUN
dpc-2310	46	23	for	for	ADP
dpc-2310	46	24	dry	dry	ADJ
dpc-2310	46	25	skin	skin	NOUN
dpc-2310	46	26	conditions	condition	NOUN
dpc-2310	46	27	and	and	CCONJ
dpc-2310	46	28	patients	patient	NOUN
dpc-2310	46	29	have	have	VERB
dpc-2310	46	30	to	to	PART
dpc-2310	46	31	continue	continue	VERB
dpc-2310	46	32	the	the	DET
dpc-2310	46	33	use	use	NOUN
dpc-2310	46	34	of	of	ADP
dpc-2310	46	35	moisturizers	moisturizer	NOUN
dpc-2310	46	36	[	[	X
dpc-2310	46	37	12	12	NUM
dpc-2310	46	38	]	]	PUNCT
dpc-2310	46	39	.	.	PUNCT
dpc-2310	47	1	topical	topical	ADJ
dpc-2310	47	2	corticosteroids	corticosteroid	NOUN
dpc-2310	47	3	topical	topical	ADJ
dpc-2310	47	4	corticosteroids	corticosteroid	NOUN
dpc-2310	47	5	(	(	PUNCT
dpc-2310	47	6	tcs	tcs	NOUN
dpc-2310	47	7	)	)	PUNCT
dpc-2310	47	8	inhibit	inhibit	VERB
dpc-2310	47	9	the	the	DET
dpc-2310	47	10	antigen	antigen	NOUN
dpc-2310	47	11	processing	processing	NOUN
dpc-2310	47	12	and	and	CCONJ
dpc-2310	47	13	suppress	suppress	VERB
dpc-2310	47	14	the	the	DET
dpc-2310	47	15	release	release	NOUN
dpc-2310	47	16	of	of	ADP
dpc-2310	47	17	pro	pro	ADJ
dpc-2310	47	18	-	-	ADJ
dpc-2310	47	19	inflammatory	inflammatory	ADJ
dpc-2310	47	20	cytokines	cytokine	NOUN
dpc-2310	47	21	,	,	PUNCT
dpc-2310	47	22	acting	act	VERB
dpc-2310	47	23	on	on	ADP
dpc-2310	47	24	a	a	DET
dpc-2310	47	25	variety	variety	NOUN
dpc-2310	47	26	of	of	ADP
dpc-2310	47	27	immune	immune	ADJ
dpc-2310	47	28	cells	cell	NOUN
dpc-2310	47	29	,	,	PUNCT
dpc-2310	47	30	including	include	VERB
dpc-2310	47	31	t	t	PROPN
dpc-2310	47	32	lymphocytes	lymphocyte	NOUN
dpc-2310	47	33	,	,	PUNCT
dpc-2310	47	34	monocytes	monocyte	NOUN
dpc-2310	47	35	,	,	PUNCT
dpc-2310	47	36	macrophages	macrophage	NOUN
dpc-2310	47	37	,	,	PUNCT
dpc-2310	47	38	and	and	CCONJ
dpc-2310	47	39	dendritic	dendritic	ADJ
dpc-2310	47	40	cells	cell	NOUN
dpc-2310	47	41	.	.	PUNCT
dpc-2310	48	1	their	their	PRON
dpc-2310	48	2	efficacy	efficacy	NOUN
dpc-2310	48	3	has	have	AUX
dpc-2310	48	4	been	be	AUX
dpc-2310	48	5	demonstrated	demonstrate	VERB
dpc-2310	48	6	,	,	PUNCT
dpc-2310	48	7	with	with	ADP
dpc-2310	48	8	more	more	ADJ
dpc-2310	48	9	than	than	ADP
dpc-2310	48	10	110	110	NUM
dpc-2310	48	11	different	different	ADJ
dpc-2310	48	12	randomized	randomized	ADJ
dpc-2310	48	13	controlled	control	VERB
dpc-2310	48	14	trials	trial	NOUN
dpc-2310	48	15	[	[	X
dpc-2310	48	16	5	5	NUM
dpc-2310	48	17	]	]	PUNCT
dpc-2310	48	18	.	.	PUNCT
dpc-2310	49	1	twice	twice	ADJ
dpc-2310	49	2	daily	daily	ADJ
dpc-2310	49	3	application	application	NOUN
dpc-2310	49	4	of	of	ADP
dpc-2310	49	5	corticosteroids	corticosteroid	NOUN
dpc-2310	49	6	is	be	AUX
dpc-2310	49	7	generally	generally	ADV
dpc-2310	49	8	recommended	recommend	VERB
dpc-2310	49	9	for	for	ADP
dpc-2310	49	10	the	the	DET
dpc-2310	49	11	treatment	treatment	NOUN
dpc-2310	49	12	of	of	ADP
dpc-2310	49	13	ad	ad	NOUN
dpc-2310	49	14	;	;	PUNCT
dpc-2310	49	15	however	however	ADV
dpc-2310	49	16	,	,	PUNCT
dpc-2310	49	17	evidence	evidence	NOUN
dpc-2310	49	18	suggests	suggest	VERB
dpc-2310	49	19	that	that	SCONJ
dpc-2310	49	20	once	once	SCONJ
dpc-2310	49	21	daily	daily	ADJ
dpc-2310	49	22	application	application	NOUN
dpc-2310	49	23	may	may	AUX
dpc-2310	49	24	be	be	AUX
dpc-2310	49	25	sufficient	sufficient	ADJ
dpc-2310	49	26	.	.	PUNCT
dpc-2310	50	1	as	as	SCONJ
dpc-2310	50	2	maintenance	maintenance	NOUN
dpc-2310	50	3	therapy	therapy	NOUN
dpc-2310	50	4	to	to	PART
dpc-2310	50	5	reduce	reduce	VERB
dpc-2310	50	6	the	the	DET
dpc-2310	50	7	number	number	NOUN
dpc-2310	50	8	of	of	ADP
dpc-2310	50	9	relapses	relapse	NOUN
dpc-2310	50	10	,	,	PUNCT
dpc-2310	50	11	a	a	DET
dpc-2310	50	12	“	"	PUNCT
dpc-2310	50	13	proactive	proactive	ADJ
dpc-2310	50	14	”	"	PUNCT
dpc-2310	50	15	approach	approach	NOUN
dpc-2310	50	16	can	can	AUX
dpc-2310	50	17	be	be	AUX
dpc-2310	50	18	prescript	prescript	ADJ
dpc-2310	50	19	.	.	PUNCT
dpc-2310	51	1	it	it	PRON
dpc-2310	51	2	consists	consist	VERB
dpc-2310	51	3	of	of	ADP
dpc-2310	51	4	applying	apply	VERB
dpc-2310	51	5	tcs	tcs	NOUN
dpc-2310	51	6	intermittently	intermittently	ADV
dpc-2310	51	7	once	once	ADV
dpc-2310	51	8	or	or	CCONJ
dpc-2310	51	9	twice	twice	DET
dpc-2310	51	10	a	a	DET
dpc-2310	51	11	week	week	NOUN
dpc-2310	51	12	in	in	ADP
dpc-2310	51	13	the	the	DET
dpc-2310	51	14	areas	area	NOUN
dpc-2310	51	15	most	most	ADV
dpc-2310	51	16	prone	prone	ADJ
dpc-2310	51	17	to	to	PART
dpc-2310	51	18	relapse	relapse	VERB
dpc-2310	51	19	,	,	PUNCT
dpc-2310	51	20	even	even	ADV
dpc-2310	51	21	when	when	SCONJ
dpc-2310	51	22	no	no	DET
dpc-2310	51	23	inflammatory	inflammatory	ADJ
dpc-2310	51	24	lesions	lesion	NOUN
dpc-2310	51	25	are	be	AUX
dpc-2310	51	26	visible	visible	ADJ
dpc-2310	51	27	.	.	PUNCT
dpc-2310	52	1	the	the	DET
dpc-2310	52	2	chronos	chronos	PROPN
dpc-2310	52	3	study	study	NOUN
dpc-2310	52	4	examined	examine	VERB
dpc-2310	52	5	the	the	DET
dpc-2310	52	6	use	use	NOUN
dpc-2310	52	7	of	of	ADP
dpc-2310	52	8	dupilumab	dupilumab	NOUN
dpc-2310	52	9	combined	combine	VERB
dpc-2310	52	10	with	with	ADP
dpc-2310	52	11	topical	topical	ADJ
dpc-2310	52	12	corticosteroids	corticosteroid	NOUN
dpc-2310	52	13	versus	versus	ADP
dpc-2310	52	14	placebo	placebo	NOUN
dpc-2310	52	15	in	in	ADP
dpc-2310	52	16	52	52	NUM
dpc-2310	52	17	weeks	week	NOUN
dpc-2310	52	18	of	of	ADP
dpc-2310	52	19	treatment	treatment	NOUN
dpc-2310	52	20	.	.	PUNCT
dpc-2310	53	1	thanks	thank	NOUN
dpc-2310	53	2	to	to	ADP
dpc-2310	53	3	the	the	DET
dpc-2310	53	4	combination	combination	NOUN
dpc-2310	53	5	with	with	ADP
dpc-2310	53	6	topical	topical	ADJ
dpc-2310	53	7	corticosteroids	corticosteroid	NOUN
dpc-2310	53	8	,	,	PUNCT
dpc-2310	53	9	10	10	NUM
dpc-2310	53	10	%	%	NOUN
dpc-2310	53	11	of	of	ADP
dpc-2310	53	12	patients	patient	NOUN
dpc-2310	53	13	more	more	ADJ
dpc-2310	53	14	than	than	ADP
dpc-2310	53	15	in	in	ADP
dpc-2310	53	16	the	the	DET
dpc-2310	53	17	solo	solo	NOUN
dpc-2310	53	18	studies	study	NOUN
dpc-2310	53	19	(	(	PUNCT
dpc-2310	53	20	that	that	PRON
dpc-2310	53	21	have	have	AUX
dpc-2310	53	22	tested	test	VERB
dpc-2310	53	23	just	just	ADV
dpc-2310	53	24	dupilumab	dupilumab	NOUN
dpc-2310	53	25	versus	versus	ADP
dpc-2310	53	26	placebo	placebo	NOUN
dpc-2310	53	27	)	)	PUNCT
dpc-2310	53	28	achieved	achieve	VERB
dpc-2310	53	29	a	a	DET
dpc-2310	53	30	75	75	NUM
dpc-2310	53	31	%	%	NOUN
dpc-2310	53	32	reduction	reduction	NOUN
dpc-2310	53	33	in	in	ADP
dpc-2310	53	34	easi	easi	ADJ
dpc-2310	53	35	score	score	NOUN
dpc-2310	53	36	[	[	X
dpc-2310	53	37	13	13	NUM
dpc-2310	53	38	]	]	PUNCT
dpc-2310	53	39	.	.	PUNCT
dpc-2310	54	1	wet	wet	ADJ
dpc-2310	54	2	wrap	wrap	NOUN
dpc-2310	54	3	therapy	therapy	NOUN
dpc-2310	54	4	the	the	DET
dpc-2310	54	5	wet	wet	ADJ
dpc-2310	54	6	wrap	wrap	NOUN
dpc-2310	54	7	therapy	therapy	NOUN
dpc-2310	54	8	(	(	PUNCT
dpc-2310	54	9	wwt	wwt	PROPN
dpc-2310	54	10	)	)	PUNCT
dpc-2310	54	11	is	be	AUX
dpc-2310	54	12	a	a	DET
dpc-2310	54	13	method	method	NOUN
dpc-2310	54	14	to	to	PART
dpc-2310	54	15	quickly	quickly	ADV
dpc-2310	54	16	reduce	reduce	VERB
dpc-2310	54	17	ad	ad	NOUN
dpc-2310	54	18	severity	severity	NOUN
dpc-2310	54	19	,	,	PUNCT
dpc-2310	54	20	used	use	VERB
dpc-2310	54	21	for	for	ADP
dpc-2310	54	22	significant	significant	ADJ
dpc-2310	54	23	flares	flare	NOUN
dpc-2310	54	24	and	and	CCONJ
dpc-2310	54	25	recalcitrant	recalcitrant	ADJ
dpc-2310	54	26	disease	disease	NOUN
dpc-2310	54	27	.	.	PUNCT
dpc-2310	55	1	it	it	PRON
dpc-2310	55	2	consists	consist	VERB
dpc-2310	55	3	in	in	ADP
dpc-2310	55	4	the	the	DET
dpc-2310	55	5	application	application	NOUN
dpc-2310	55	6	of	of	ADP
dpc-2310	55	7	topical	topical	ADJ
dpc-2310	55	8	agent	agent	NOUN
dpc-2310	55	9	(	(	PUNCT
dpc-2310	55	10	tcs	tcs	NOUN
dpc-2310	55	11	or	or	CCONJ
dpc-2310	55	12	moisturizers	moisturizer	NOUN
dpc-2310	55	13	or	or	CCONJ
dpc-2310	55	14	combination	combination	NOUN
dpc-2310	55	15	of	of	ADP
dpc-2310	55	16	both	both	PRON
dpc-2310	55	17	)	)	PUNCT
dpc-2310	55	18	covered	cover	VERB
dpc-2310	55	19	by	by	ADP
dpc-2310	55	20	a	a	DET
dpc-2310	55	21	wetted	wet	VERB
dpc-2310	55	22	first	first	ADJ
dpc-2310	55	23	layer	layer	NOUN
dpc-2310	55	24	of	of	ADP
dpc-2310	55	25	tubular	tubular	ADJ
dpc-2310	55	26	bandages	bandage	NOUN
dpc-2310	55	27	,	,	PUNCT
dpc-2310	55	28	gauze	gauze	NOUN
dpc-2310	55	29	,	,	PUNCT
dpc-2310	55	30	or	or	CCONJ
dpc-2310	55	31	a	a	DET
dpc-2310	55	32	cotton	cotton	NOUN
dpc-2310	55	33	suit	suit	NOUN
dpc-2310	55	34	,	,	PUNCT
dpc-2310	55	35	followed	follow	VERB
dpc-2310	55	36	by	by	ADP
dpc-2310	55	37	a	a	DET
dpc-2310	55	38	second	second	ADJ
dpc-2310	55	39	dry	dry	ADJ
dpc-2310	55	40	layer	layer	NOUN
dpc-2310	55	41	.	.	PUNCT
dpc-2310	56	1	wwt	wwt	PROPN
dpc-2310	56	2	increases	increase	VERB
dpc-2310	56	3	the	the	DET
dpc-2310	56	4	penetration	penetration	NOUN
dpc-2310	56	5	of	of	ADP
dpc-2310	56	6	topical	topical	ADJ
dpc-2310	56	7	therapy	therapy	NOUN
dpc-2310	56	8	and	and	CCONJ
dpc-2310	56	9	reduces	reduce	VERB
dpc-2310	56	10	the	the	DET
dpc-2310	56	11	water	water	NOUN
dpc-2310	56	12	loss	loss	NOUN
dpc-2310	56	13	.	.	PUNCT
dpc-2310	57	1	the	the	DET
dpc-2310	57	2	wrap	wrap	NOUN
dpc-2310	57	3	can	can	AUX
dpc-2310	57	4	be	be	AUX
dpc-2310	57	5	worn	wear	VERB
dpc-2310	57	6	from	from	ADP
dpc-2310	57	7	several	several	ADJ
dpc-2310	57	8	hours	hour	NOUN
dpc-2310	57	9	to	to	ADP
dpc-2310	57	10	24	24	NUM
dpc-2310	57	11	hours	hour	NOUN
dpc-2310	57	12	at	at	ADP
dpc-2310	57	13	a	a	DET
dpc-2310	57	14	time	time	NOUN
dpc-2310	57	15	,	,	PUNCT
dpc-2310	57	16	depending	depend	VERB
dpc-2310	57	17	on	on	ADP
dpc-2310	57	18	patient	patient	ADJ
dpc-2310	57	19	tolerance	tolerance	NOUN
dpc-2310	57	20	review	review	NOUN
dpc-2310	57	21	|	|	ADV
dpc-2310	57	22	dermatol	dermatol	ADJ
dpc-2310	57	23	pract	pract	NOUN
dpc-2310	57	24	concept	concept	NOUN
dpc-2310	57	25	.	.	PUNCT
dpc-2310	58	1	2022;12(1):e2022155	2022;12(1):e2022155	NUM
dpc-2310	58	2	3	3	NUM
dpc-2310	58	3	and	and	CCONJ
dpc-2310	58	4	the	the	DET
dpc-2310	58	5	application	application	NOUN
dpc-2310	58	6	can	can	AUX
dpc-2310	58	7	be	be	AUX
dpc-2310	58	8	repeated	repeat	VERB
dpc-2310	58	9	for	for	ADP
dpc-2310	58	10	several	several	ADJ
dpc-2310	58	11	days	day	NOUN
dpc-2310	58	12	up	up	ADP
dpc-2310	58	13	to	to	PART
dpc-2310	58	14	2	2	NUM
dpc-2310	58	15	weeks	week	NOUN
dpc-2310	58	16	.	.	PUNCT
dpc-2310	59	1	the	the	DET
dpc-2310	59	2	major	major	ADJ
dpc-2310	59	3	limitation	limitation	NOUN
dpc-2310	59	4	of	of	ADP
dpc-2310	59	5	this	this	DET
dpc-2310	59	6	technique	technique	NOUN
dpc-2310	59	7	is	be	AUX
dpc-2310	59	8	represented	represent	VERB
dpc-2310	59	9	by	by	ADP
dpc-2310	59	10	the	the	DET
dpc-2310	59	11	lack	lack	NOUN
dpc-2310	59	12	of	of	ADP
dpc-2310	59	13	practicality	practicality	NOUN
dpc-2310	59	14	and	and	CCONJ
dpc-2310	59	15	the	the	DET
dpc-2310	59	16	low	low	ADJ
dpc-2310	59	17	tolerance	tolerance	NOUN
dpc-2310	59	18	for	for	ADP
dpc-2310	59	19	patients	patient	NOUN
dpc-2310	59	20	,	,	PUNCT
dpc-2310	59	21	especially	especially	ADV
dpc-2310	59	22	if	if	SCONJ
dpc-2310	59	23	children	child	NOUN
dpc-2310	59	24	[	[	X
dpc-2310	59	25	8,9	8,9	NUM
dpc-2310	59	26	]	]	PUNCT
dpc-2310	59	27	.	.	PUNCT
dpc-2310	60	1	topical	topical	ADJ
dpc-2310	60	2	calcineurin	calcineurin	NOUN
dpc-2310	60	3	inhibitors	inhibitor	NOUN
dpc-2310	60	4	topical	topical	ADJ
dpc-2310	60	5	calcineurin	calcineurin	NOUN
dpc-2310	60	6	inhibitors	inhibitor	NOUN
dpc-2310	60	7	(	(	PUNCT
dpc-2310	60	8	tcis	tcis	NOUN
dpc-2310	60	9	)	)	PUNCT
dpc-2310	60	10	inhibit	inhibit	VERB
dpc-2310	60	11	calcineurin	calcineurin	NOUN
dpc-2310	60	12	-	-	PUNCT
dpc-2310	60	13	dependent	dependent	ADJ
dpc-2310	60	14	t	t	NOUN
dpc-2310	60	15	-	-	PUNCT
dpc-2310	60	16	cell	cell	NOUN
dpc-2310	60	17	activation	activation	NOUN
dpc-2310	60	18	,	,	PUNCT
dpc-2310	60	19	blocking	block	VERB
dpc-2310	60	20	the	the	DET
dpc-2310	60	21	production	production	NOUN
dpc-2310	60	22	of	of	ADP
dpc-2310	60	23	pro	pro	ADJ
dpc-2310	60	24	-	-	ADJ
dpc-2310	60	25	inflammatory	inflammatory	ADJ
dpc-2310	60	26	cytokines	cytokine	NOUN
dpc-2310	60	27	.	.	PUNCT
dpc-2310	61	1	two	two	NUM
dpc-2310	61	2	types	type	NOUN
dpc-2310	61	3	of	of	ADP
dpc-2310	61	4	tcis	tcis	NOUN
dpc-2310	61	5	are	be	AUX
dpc-2310	61	6	available	available	ADJ
dpc-2310	61	7	:	:	PUNCT
dpc-2310	61	8	tacrolimus	tacrolimus	PROPN
dpc-2310	61	9	ointment	ointment	NOUN
dpc-2310	61	10	(	(	PUNCT
dpc-2310	61	11	0.03	0.03	NUM
dpc-2310	61	12	%	%	NOUN
dpc-2310	61	13	and	and	CCONJ
dpc-2310	61	14	0.1	0.1	NUM
dpc-2310	61	15	%	%	NOUN
dpc-2310	61	16	strengths	strength	NOUN
dpc-2310	61	17	)	)	PUNCT
dpc-2310	61	18	and	and	CCONJ
dpc-2310	61	19	pimecrolimus	pimecrolimus	VERB
dpc-2310	61	20	cream	cream	NOUN
dpc-2310	61	21	(	(	PUNCT
dpc-2310	61	22	1	1	NUM
dpc-2310	61	23	%	%	NOUN
dpc-2310	61	24	strength	strength	NOUN
dpc-2310	61	25	)	)	PUNCT
dpc-2310	61	26	.	.	PUNCT
dpc-2310	62	1	tcis	tcis	NOUN
dpc-2310	62	2	are	be	AUX
dpc-2310	62	3	recommended	recommend	VERB
dpc-2310	62	4	and	and	CCONJ
dpc-2310	62	5	effective	effective	ADJ
dpc-2310	62	6	for	for	ADP
dpc-2310	62	7	acute	acute	ADJ
dpc-2310	62	8	and	and	CCONJ
dpc-2310	62	9	chronic	chronic	ADJ
dpc-2310	62	10	treatment	treatment	NOUN
dpc-2310	62	11	,	,	PUNCT
dpc-2310	62	12	twice	twice	DET
dpc-2310	62	13	a	a	DET
dpc-2310	62	14	day	day	NOUN
dpc-2310	62	15	,	,	PUNCT
dpc-2310	62	16	as	as	ADV
dpc-2310	62	17	well	well	ADV
dpc-2310	62	18	as	as	ADP
dpc-2310	62	19	maintenance	maintenance	NOUN
dpc-2310	62	20	,	,	PUNCT
dpc-2310	62	21	in	in	ADP
dpc-2310	62	22	both	both	DET
dpc-2310	62	23	adults	adult	NOUN
dpc-2310	62	24	and	and	CCONJ
dpc-2310	62	25	children	child	NOUN
dpc-2310	62	26	with	with	ADP
dpc-2310	62	27	ad	ad	NOUN
dpc-2310	62	28	.	.	PUNCT
dpc-2310	63	1	they	they	PRON
dpc-2310	63	2	can	can	AUX
dpc-2310	63	3	be	be	AUX
dpc-2310	63	4	used	use	VERB
dpc-2310	63	5	as	as	ADP
dpc-2310	63	6	steroid	steroid	NOUN
dpc-2310	63	7	-	-	PUNCT
dpc-2310	63	8	sparing	spare	VERB
dpc-2310	63	9	agents	agent	NOUN
dpc-2310	63	10	in	in	ADP
dpc-2310	63	11	long	long	ADJ
dpc-2310	63	12	term	term	NOUN
dpc-2310	63	13	therapy	therapy	NOUN
dpc-2310	63	14	because	because	SCONJ
dpc-2310	63	15	they	they	PRON
dpc-2310	63	16	do	do	AUX
dpc-2310	63	17	not	not	PART
dpc-2310	63	18	cause	cause	VERB
dpc-2310	63	19	cutaneous	cutaneous	ADJ
dpc-2310	63	20	atrophy	atrophy	NOUN
dpc-2310	63	21	and	and	CCONJ
dpc-2310	63	22	can	can	AUX
dpc-2310	63	23	be	be	AUX
dpc-2310	63	24	used	use	VERB
dpc-2310	63	25	in	in	ADP
dpc-2310	63	26	sensitive	sensitive	ADJ
dpc-2310	63	27	areas	area	NOUN
dpc-2310	63	28	,	,	PUNCT
dpc-2310	63	29	such	such	ADJ
dpc-2310	63	30	as	as	ADP
dpc-2310	63	31	the	the	DET
dpc-2310	63	32	face	face	NOUN
dpc-2310	63	33	,	,	PUNCT
dpc-2310	63	34	skin	skin	NOUN
dpc-2310	63	35	folds	fold	NOUN
dpc-2310	63	36	and	and	CCONJ
dpc-2310	63	37	genitals	genital	NOUN
dpc-2310	63	38	.	.	PUNCT
dpc-2310	64	1	tacrolimus	tacrolimus	NOUN
dpc-2310	64	2	0.03	0.03	NUM
dpc-2310	64	3	%	%	NOUN
dpc-2310	64	4	ointment	ointment	NOUN
dpc-2310	64	5	and	and	CCONJ
dpc-2310	64	6	pimecrolimus	pimecrolimus	NOUN
dpc-2310	64	7	cream	cream	NOUN
dpc-2310	64	8	are	be	AUX
dpc-2310	64	9	indicated	indicate	VERB
dpc-2310	64	10	for	for	ADP
dpc-2310	64	11	use	use	NOUN
dpc-2310	64	12	in	in	ADP
dpc-2310	64	13	individuals	individual	NOUN
dpc-2310	64	14	aged	age	VERB
dpc-2310	64	15	2	2	NUM
dpc-2310	64	16	years	year	NOUN
dpc-2310	64	17	and	and	CCONJ
dpc-2310	64	18	older	old	ADJ
dpc-2310	64	19	,	,	PUNCT
dpc-2310	64	20	while	while	SCONJ
dpc-2310	64	21	tacrolimus	tacrolimus	NOUN
dpc-2310	64	22	0.1	0.1	NUM
dpc-2310	64	23	%	%	NOUN
dpc-2310	64	24	strength	strength	NOUN
dpc-2310	64	25	is	be	AUX
dpc-2310	64	26	only	only	ADV
dpc-2310	64	27	approved	approve	VERB
dpc-2310	64	28	in	in	ADP
dpc-2310	64	29	those	those	PRON
dpc-2310	64	30	over	over	ADP
dpc-2310	64	31	age	age	NOUN
dpc-2310	64	32	15	15	NUM
dpc-2310	64	33	years	year	NOUN
dpc-2310	64	34	.	.	PUNCT
dpc-2310	65	1	proactive	proactive	ADJ
dpc-2310	65	2	,	,	PUNCT
dpc-2310	65	3	intermittent	intermittent	ADJ
dpc-2310	65	4	use	use	NOUN
dpc-2310	65	5	of	of	ADP
dpc-2310	65	6	tcis	tcis	NOUN
dpc-2310	65	7	as	as	ADP
dpc-2310	65	8	maintenance	maintenance	NOUN
dpc-2310	65	9	therapy	therapy	NOUN
dpc-2310	65	10	(	(	PUNCT
dpc-2310	65	11	2–3	2–3	PROPN
dpc-2310	65	12	times	time	NOUN
dpc-2310	65	13	a	a	DET
dpc-2310	65	14	week	week	NOUN
dpc-2310	65	15	)	)	PUNCT
dpc-2310	65	16	on	on	ADP
dpc-2310	65	17	areas	area	NOUN
dpc-2310	65	18	that	that	PRON
dpc-2310	65	19	commonly	commonly	ADV
dpc-2310	65	20	flare	flare	NOUN
dpc-2310	65	21	is	be	AUX
dpc-2310	65	22	recommended	recommend	VERB
dpc-2310	65	23	to	to	PART
dpc-2310	65	24	prevent	prevent	VERB
dpc-2310	65	25	relapses	relapse	NOUN
dpc-2310	65	26	and	and	CCONJ
dpc-2310	65	27	is	be	AUX
dpc-2310	65	28	more	more	ADV
dpc-2310	65	29	effective	effective	ADJ
dpc-2310	65	30	than	than	ADP
dpc-2310	65	31	the	the	DET
dpc-2310	65	32	use	use	NOUN
dpc-2310	65	33	of	of	ADP
dpc-2310	65	34	emollients	emollient	NOUN
dpc-2310	65	35	alone	alone	ADV
dpc-2310	65	36	.	.	PUNCT
dpc-2310	66	1	this	this	DET
dpc-2310	66	2	strategy	strategy	NOUN
dpc-2310	66	3	has	have	AUX
dpc-2310	66	4	been	be	AUX
dpc-2310	66	5	tested	test	VERB
dpc-2310	66	6	for	for	ADP
dpc-2310	66	7	up	up	ADP
dpc-2310	66	8	to	to	PART
dpc-2310	66	9	1	1	NUM
dpc-2310	66	10	year	year	NOUN
dpc-2310	66	11	,	,	PUNCT
dpc-2310	66	12	without	without	ADP
dpc-2310	66	13	significant	significant	ADJ
dpc-2310	66	14	adverse	adverse	ADJ
dpc-2310	66	15	events	event	NOUN
dpc-2310	66	16	.	.	PUNCT
dpc-2310	67	1	the	the	DET
dpc-2310	67	2	most	most	ADV
dpc-2310	67	3	common	common	ADJ
dpc-2310	67	4	side	side	NOUN
dpc-2310	67	5	effects	effect	NOUN
dpc-2310	67	6	are	be	AUX
dpc-2310	67	7	local	local	ADJ
dpc-2310	67	8	reactions	reaction	NOUN
dpc-2310	67	9	such	such	ADJ
dpc-2310	67	10	as	as	ADP
dpc-2310	67	11	stinging	sting	VERB
dpc-2310	67	12	and	and	CCONJ
dpc-2310	67	13	burning	burning	NOUN
dpc-2310	67	14	.	.	PUNCT
dpc-2310	68	1	tcis	tcis	NOUN
dpc-2310	68	2	may	may	AUX
dpc-2310	68	3	be	be	AUX
dpc-2310	68	4	combined	combine	VERB
dpc-2310	68	5	with	with	ADP
dpc-2310	68	6	tcs	tcs	NOUN
dpc-2310	69	1	[	[	X
dpc-2310	69	2	5	5	NUM
dpc-2310	69	3	]	]	PUNCT
dpc-2310	69	4	.	.	PUNCT
dpc-2310	70	1	for	for	SCONJ
dpc-2310	70	2	patients	patient	NOUN
dpc-2310	70	3	undergoing	undergo	VERB
dpc-2310	70	4	dupilumab	dupilumab	NOUN
dpc-2310	70	5	injections	injection	NOUN
dpc-2310	70	6	,	,	PUNCT
dpc-2310	70	7	tacrolimus	tacrolimus	NOUN
dpc-2310	70	8	ointment	ointment	NOUN
dpc-2310	70	9	and	and	CCONJ
dpc-2310	70	10	pimecrolimus	pimecrolimus	NOUN
dpc-2310	70	11	cream	cream	NOUN
dpc-2310	70	12	may	may	AUX
dpc-2310	70	13	be	be	AUX
dpc-2310	70	14	helpful	helpful	ADJ
dpc-2310	70	15	to	to	PART
dpc-2310	70	16	treat	treat	VERB
dpc-2310	70	17	facial	facial	ADJ
dpc-2310	70	18	eczema	eczema	NOUN
dpc-2310	70	19	(	(	PUNCT
dpc-2310	70	20	that	that	PRON
dpc-2310	70	21	responds	respond	VERB
dpc-2310	70	22	later	later	ADV
dpc-2310	70	23	to	to	PART
dpc-2310	70	24	dupilumab	dupilumab	VERB
dpc-2310	70	25	)	)	PUNCT
dpc-2310	70	26	and	and	CCONJ
dpc-2310	70	27	peripalpebral	peripalpebral	ADJ
dpc-2310	70	28	dermatitis	dermatitis	NOUN
dpc-2310	70	29	(	(	PUNCT
dpc-2310	70	30	as	as	ADP
dpc-2310	70	31	a	a	DET
dpc-2310	70	32	prevention	prevention	NOUN
dpc-2310	70	33	of	of	ADP
dpc-2310	70	34	dupilumab	dupilumab	NOUN
dpc-2310	70	35	associated	associate	VERB
dpc-2310	70	36	conjunctivitis	conjunctivitis	NOUN
dpc-2310	70	37	)	)	PUNCT
dpc-2310	70	38	.	.	PUNCT
dpc-2310	71	1	conjunctivitis	conjunctivitis	NOUN
dpc-2310	71	2	is	be	AUX
dpc-2310	71	3	the	the	DET
dpc-2310	71	4	most	most	ADV
dpc-2310	71	5	common	common	ADJ
dpc-2310	71	6	side	side	NOUN
dpc-2310	71	7	effect	effect	NOUN
dpc-2310	71	8	of	of	ADP
dpc-2310	71	9	dupilumab	dupilumab	NOUN
dpc-2310	71	10	[	[	X
dpc-2310	71	11	14	14	NUM
dpc-2310	71	12	]	]	PUNCT
dpc-2310	71	13	.	.	PUNCT
dpc-2310	72	1	the	the	DET
dpc-2310	72	2	prescription	prescription	NOUN
dpc-2310	72	3	of	of	ADP
dpc-2310	72	4	trehalose/	trehalose/	NUM
dpc-2310	72	5	hyaluroate	hyaluroate	PROPN
dpc-2310	72	6	tear	tear	PROPN
dpc-2310	72	7	substitute	substitute	PROPN
dpc-2310	72	8	and	and	CCONJ
dpc-2310	72	9	the	the	DET
dpc-2310	72	10	treatment	treatment	NOUN
dpc-2310	72	11	of	of	ADP
dpc-2310	72	12	peripalpebral	peripalpebral	ADJ
dpc-2310	72	13	and	and	CCONJ
dpc-2310	72	14	facial	facial	ADJ
dpc-2310	72	15	eczema	eczema	NOUN
dpc-2310	72	16	with	with	ADP
dpc-2310	72	17	topical	topical	ADJ
dpc-2310	72	18	therapy	therapy	NOUN
dpc-2310	72	19	reduce	reduce	VERB
dpc-2310	72	20	the	the	DET
dpc-2310	72	21	incidence	incidence	NOUN
dpc-2310	72	22	of	of	ADP
dpc-2310	72	23	dupilumab	dupilumab	NOUN
dpc-2310	72	24	-	-	PUNCT
dpc-2310	72	25	associated	associate	VERB
dpc-2310	72	26	conjunctivitis	conjunctivitis	NOUN
dpc-2310	72	27	(	(	PUNCT
dpc-2310	72	28	incidence	incidence	NOUN
dpc-2310	72	29	equal	equal	ADJ
dpc-2310	72	30	to	to	ADP
dpc-2310	72	31	5	5	NUM
dpc-2310	72	32	%	%	NOUN
dpc-2310	72	33	with	with	ADP
dpc-2310	72	34	preventive	preventive	ADJ
dpc-2310	72	35	therapy	therapy	NOUN
dpc-2310	72	36	versus	versus	ADP
dpc-2310	72	37	an	an	DET
dpc-2310	72	38	incidence	incidence	NOUN
dpc-2310	72	39	of	of	ADP
dpc-2310	72	40	8	8	NUM
dpc-2310	72	41	%	%	NOUN
dpc-2310	72	42	and	and	CCONJ
dpc-2310	72	43	8	8	NUM
dpc-2310	72	44	-	-	SYM
dpc-2310	72	45	23	23	NUM
dpc-2310	72	46	%	%	NOUN
dpc-2310	72	47	without	without	ADP
dpc-2310	72	48	preventive	preventive	ADJ
dpc-2310	72	49	therapy	therapy	NOUN
dpc-2310	72	50	,	,	PUNCT
dpc-2310	72	51	according	accord	VERB
dpc-2310	72	52	to	to	ADP
dpc-2310	72	53	trial	trial	NOUN
dpc-2310	72	54	studies	study	NOUN
dpc-2310	72	55	and	and	CCONJ
dpc-2310	72	56	real	real	ADJ
dpc-2310	72	57	life	life	NOUN
dpc-2310	72	58	studies	study	NOUN
dpc-2310	72	59	respectively	respectively	ADV
dpc-2310	72	60	)	)	PUNCT
dpc-2310	73	1	[	[	X
dpc-2310	73	2	15	15	NUM
dpc-2310	73	3	]	]	PUNCT
dpc-2310	73	4	.	.	PUNCT
dpc-2310	74	1	moreover	moreover	ADV
dpc-2310	74	2	,	,	PUNCT
dpc-2310	74	3	new	new	ADJ
dpc-2310	74	4	emerging	emerge	VERB
dpc-2310	74	5	problems	problem	NOUN
dpc-2310	74	6	are	be	AUX
dpc-2310	74	7	reported	report	VERB
dpc-2310	74	8	in	in	ADP
dpc-2310	74	9	literature	literature	NOUN
dpc-2310	74	10	:	:	PUNCT
dpc-2310	74	11	recalcitrant	recalcitrant	ADJ
dpc-2310	74	12	(	(	PUNCT
dpc-2310	74	13	pre	pre	ADJ
dpc-2310	74	14	-	-	ADJ
dpc-2310	74	15	existing	existing	ADJ
dpc-2310	74	16	biological	biological	ADJ
dpc-2310	74	17	therapy	therapy	NOUN
dpc-2310	74	18	)	)	PUNCT
dpc-2310	74	19	and	and	CCONJ
dpc-2310	74	20	dupilumab	dupilumab	NOUN
dpc-2310	74	21	-	-	PUNCT
dpc-2310	74	22	associated	associate	VERB
dpc-2310	74	23	(	(	PUNCT
dpc-2310	74	24	probably	probably	ADV
dpc-2310	74	25	induced	induce	VERB
dpc-2310	74	26	by	by	ADP
dpc-2310	74	27	biological	biological	ADJ
dpc-2310	74	28	therapy	therapy	NOUN
dpc-2310	74	29	)	)	PUNCT
dpc-2310	74	30	face	face	NOUN
dpc-2310	74	31	and	and	CCONJ
dpc-2310	74	32	neck	neck	NOUN
dpc-2310	74	33	dermatitis	dermatitis	NOUN
dpc-2310	74	34	are	be	AUX
dpc-2310	74	35	described	describe	VERB
dpc-2310	74	36	and	and	CCONJ
dpc-2310	74	37	can	can	AUX
dpc-2310	74	38	benefit	benefit	VERB
dpc-2310	74	39	by	by	ADP
dpc-2310	74	40	topical	topical	ADJ
dpc-2310	74	41	therapy	therapy	NOUN
dpc-2310	74	42	(	(	PUNCT
dpc-2310	74	43	antifungal	antifungal	NOUN
dpc-2310	74	44	-	-	PUNCT
dpc-2310	74	45	corticosteroids	corticosteroid	NOUN
dpc-2310	74	46	and	and	CCONJ
dpc-2310	74	47	tacrolimus	tacrolimus	PROPN
dpc-2310	74	48	ointment	ointment	PROPN
dpc-2310	74	49	)	)	PUNCT
dpc-2310	74	50	.	.	PUNCT
dpc-2310	75	1	various	various	ADJ
dpc-2310	75	2	etiopathogenic	etiopathogenic	ADJ
dpc-2310	75	3	mechanisms	mechanism	NOUN
dpc-2310	75	4	for	for	ADP
dpc-2310	75	5	these	these	DET
dpc-2310	75	6	new	new	ADJ
dpc-2310	75	7	regional	regional	ADJ
dpc-2310	75	8	dermatoses	dermatosis	NOUN
dpc-2310	75	9	have	have	AUX
dpc-2310	75	10	been	be	AUX
dpc-2310	75	11	proposed	propose	VERB
dpc-2310	75	12	but	but	CCONJ
dpc-2310	75	13	more	more	ADJ
dpc-2310	75	14	studies	study	NOUN
dpc-2310	75	15	are	be	AUX
dpc-2310	75	16	needed	need	VERB
dpc-2310	76	1	[	[	PUNCT
dpc-2310	76	2	16	16	NUM
dpc-2310	76	3	]	]	PUNCT
dpc-2310	76	4	.	.	PUNCT
dpc-2310	77	1	phototherapy	phototherapy	NOUN
dpc-2310	77	2	phototherapy	phototherapy	NOUN
dpc-2310	77	3	is	be	AUX
dpc-2310	77	4	used	use	VERB
dpc-2310	77	5	as	as	ADP
dpc-2310	77	6	second	second	ADJ
dpc-2310	77	7	-	-	PUNCT
dpc-2310	77	8	line	line	NOUN
dpc-2310	77	9	treatment	treatment	NOUN
dpc-2310	77	10	,	,	PUNCT
dpc-2310	77	11	after	after	ADP
dpc-2310	77	12	failure	failure	NOUN
dpc-2310	77	13	of	of	ADP
dpc-2310	77	14	first	first	ADJ
dpc-2310	77	15	-	-	PUNCT
dpc-2310	77	16	line	line	NOUN
dpc-2310	77	17	treatment	treatment	NOUN
dpc-2310	77	18	(	(	PUNCT
dpc-2310	77	19	emollients	emollient	NOUN
dpc-2310	77	20	,	,	PUNCT
dpc-2310	77	21	topical	topical	ADJ
dpc-2310	77	22	steroids	steroid	NOUN
dpc-2310	77	23	,	,	PUNCT
dpc-2310	77	24	and	and	CCONJ
dpc-2310	77	25	tcis	tcis	NOUN
dpc-2310	77	26	)	)	PUNCT
dpc-2310	77	27	,	,	PUNCT
dpc-2310	77	28	or	or	CCONJ
dpc-2310	77	29	as	as	ADP
dpc-2310	77	30	maintenance	maintenance	NOUN
dpc-2310	77	31	therapy	therapy	NOUN
dpc-2310	77	32	in	in	ADP
dpc-2310	77	33	patients	patient	NOUN
dpc-2310	77	34	with	with	ADP
dpc-2310	77	35	chronic	chronic	ADJ
dpc-2310	77	36	disease	disease	NOUN
dpc-2310	77	37	.	.	PUNCT
dpc-2310	78	1	multiple	multiple	ADJ
dpc-2310	78	2	forms	form	NOUN
dpc-2310	78	3	of	of	ADP
dpc-2310	78	4	light	light	NOUN
dpc-2310	78	5	therapy	therapy	NOUN
dpc-2310	78	6	are	be	AUX
dpc-2310	78	7	beneficial	beneficial	ADJ
dpc-2310	78	8	for	for	ADP
dpc-2310	78	9	disease	disease	NOUN
dpc-2310	78	10	and	and	CCONJ
dpc-2310	78	11	symptom	symptom	NOUN
dpc-2310	78	12	control	control	NOUN
dpc-2310	78	13	,	,	PUNCT
dpc-2310	78	14	including	include	VERB
dpc-2310	78	15	:	:	PUNCT
dpc-2310	78	16	natural	natural	ADJ
dpc-2310	78	17	sunlight	sunlight	NOUN
dpc-2310	78	18	,	,	PUNCT
dpc-2310	78	19	narrowband	narrowband	NOUN
dpc-2310	78	20	(	(	PUNCT
dpc-2310	78	21	nb	nb	NOUN
dpc-2310	78	22	)	)	PUNCT
dpc-2310	78	23	uvb	uvb	PROPN
dpc-2310	78	24	,	,	PUNCT
dpc-2310	78	25	bb	bb	NOUN
dpc-2310	78	26	-	-	PUNCT
dpc-2310	78	27	uvb	uvb	ADJ
dpc-2310	78	28	,	,	PUNCT
dpc-2310	78	29	uva	uva	PROPN
dpc-2310	78	30	,	,	PUNCT
dpc-2310	78	31	topical	topical	ADJ
dpc-2310	78	32	and	and	CCONJ
dpc-2310	78	33	systemic	systemic	ADJ
dpc-2310	78	34	puva	puva	PROPN
dpc-2310	78	35	.	.	PUNCT
dpc-2310	79	1	home	home	NOUN
dpc-2310	79	2	phototherapy	phototherapy	NOUN
dpc-2310	79	3	under	under	ADP
dpc-2310	79	4	the	the	DET
dpc-2310	79	5	direction	direction	NOUN
dpc-2310	79	6	of	of	ADP
dpc-2310	79	7	a	a	DET
dpc-2310	79	8	physician	physician	NOUN
dpc-2310	79	9	may	may	AUX
dpc-2310	79	10	be	be	AUX
dpc-2310	79	11	considered	consider	VERB
dpc-2310	79	12	for	for	ADP
dpc-2310	79	13	patients	patient	NOUN
dpc-2310	79	14	who	who	PRON
dpc-2310	79	15	are	be	AUX
dpc-2310	79	16	unable	unable	ADJ
dpc-2310	79	17	to	to	PART
dpc-2310	79	18	receive	receive	VERB
dpc-2310	79	19	phototherapy	phototherapy	NOUN
dpc-2310	79	20	in	in	ADP
dpc-2310	79	21	a	a	DET
dpc-2310	79	22	medical	medical	ADJ
dpc-2310	79	23	office	office	NOUN
dpc-2310	79	24	setting	setting	NOUN
dpc-2310	79	25	.	.	PUNCT
dpc-2310	80	1	the	the	DET
dpc-2310	80	2	light	light	ADJ
dpc-2310	80	3	modality	modality	NOUN
dpc-2310	80	4	chosen	choose	VERB
dpc-2310	80	5	should	should	AUX
dpc-2310	80	6	be	be	AUX
dpc-2310	80	7	guided	guide	VERB
dpc-2310	80	8	by	by	ADP
dpc-2310	80	9	factors	factor	NOUN
dpc-2310	80	10	such	such	ADJ
dpc-2310	80	11	as	as	ADP
dpc-2310	80	12	availability	availability	NOUN
dpc-2310	80	13	,	,	PUNCT
dpc-2310	80	14	cost	cost	NOUN
dpc-2310	80	15	,	,	PUNCT
dpc-2310	80	16	patient	patient	ADJ
dpc-2310	80	17	skin	skin	NOUN
dpc-2310	80	18	type	type	NOUN
dpc-2310	80	19	,	,	PUNCT
dpc-2310	80	20	skin	skin	NOUN
dpc-2310	80	21	cancer	cancer	NOUN
dpc-2310	80	22	history	history	NOUN
dpc-2310	80	23	,	,	PUNCT
dpc-2310	80	24	and	and	CCONJ
dpc-2310	80	25	patient	patient	ADJ
dpc-2310	80	26	use	use	NOUN
dpc-2310	80	27	of	of	ADP
dpc-2310	80	28	photosensitizing	photosensitize	VERB
dpc-2310	80	29	medications	medication	NOUN
dpc-2310	80	30	(	(	PUNCT
dpc-2310	80	31	for	for	ADP
dpc-2310	80	32	example	example	NOUN
dpc-2310	80	33	calcineurine	calcineurine	X
dpc-2310	80	34	inhibitor	inhibitor	NOUN
dpc-2310	80	35	)	)	PUNCT
dpc-2310	80	36	.	.	PUNCT
dpc-2310	81	1	the	the	DET
dpc-2310	81	2	dosing	dosing	NOUN
dpc-2310	81	3	and	and	CCONJ
dpc-2310	81	4	scheduling	scheduling	NOUN
dpc-2310	81	5	of	of	ADP
dpc-2310	81	6	light	light	NOUN
dpc-2310	81	7	should	should	AUX
dpc-2310	81	8	be	be	AUX
dpc-2310	81	9	based	base	VERB
dpc-2310	81	10	on	on	ADP
dpc-2310	81	11	minimal	minimal	ADJ
dpc-2310	81	12	erythema	erythema	ADJ
dpc-2310	81	13	dose	dose	NOUN
dpc-2310	81	14	and	and	CCONJ
dpc-2310	81	15	fitzpatrick	fitzpatrick	PROPN
dpc-2310	81	16	skin	skin	PROPN
dpc-2310	81	17	type	type	NOUN
dpc-2310	81	18	.	.	PUNCT
dpc-2310	82	1	phototherapy	phototherapy	NOUN
dpc-2310	82	2	is	be	AUX
dpc-2310	82	3	usually	usually	ADV
dpc-2310	82	4	administered	administer	VERB
dpc-2310	82	5	3	3	NUM
dpc-2310	82	6	times	time	NOUN
dpc-2310	82	7	a	a	DET
dpc-2310	82	8	week	week	NOUN
dpc-2310	82	9	.	.	PUNCT
dpc-2310	83	1	nb	nb	X
dpc-2310	83	2	-	-	ADJ
dpc-2310	83	3	uvb	uvb	NOUN
dpc-2310	83	4	is	be	AUX
dpc-2310	83	5	generally	generally	ADV
dpc-2310	83	6	the	the	DET
dpc-2310	83	7	most	most	ADV
dpc-2310	83	8	commonly	commonly	ADV
dpc-2310	83	9	recommended	recommend	VERB
dpc-2310	83	10	light	light	ADJ
dpc-2310	83	11	treatment	treatment	NOUN
dpc-2310	83	12	,	,	PUNCT
dpc-2310	83	13	considering	consider	VERB
dpc-2310	83	14	its	its	PRON
dpc-2310	83	15	low	low	ADJ
dpc-2310	83	16	risk	risk	NOUN
dpc-2310	83	17	profile	profile	NOUN
dpc-2310	83	18	and	and	CCONJ
dpc-2310	83	19	the	the	DET
dpc-2310	83	20	relative	relative	ADJ
dpc-2310	83	21	efficacy	efficacy	NOUN
dpc-2310	83	22	.	.	PUNCT
dpc-2310	84	1	several	several	ADJ
dpc-2310	84	2	common	common	ADJ
dpc-2310	84	3	adverse	adverse	ADJ
dpc-2310	84	4	effects	effect	NOUN
dpc-2310	84	5	include	include	VERB
dpc-2310	84	6	:	:	PUNCT
dpc-2310	84	7	actinic	actinic	ADJ
dpc-2310	84	8	damage	damage	NOUN
dpc-2310	84	9	,	,	PUNCT
dpc-2310	84	10	local	local	ADJ
dpc-2310	84	11	erythema	erythema	NOUN
dpc-2310	84	12	and	and	CCONJ
dpc-2310	84	13	tenderness	tenderness	NOUN
dpc-2310	84	14	,	,	PUNCT
dpc-2310	84	15	pruritus	pruritus	NOUN
dpc-2310	84	16	and	and	CCONJ
dpc-2310	84	17	burning	burn	VERB
dpc-2310	84	18	[	[	PUNCT
dpc-2310	84	19	10	10	NUM
dpc-2310	84	20	]	]	PUNCT
dpc-2310	84	21	.	.	PUNCT
dpc-2310	85	1	systemic	systemic	ADJ
dpc-2310	85	2	corticosteroids	corticosteroid	NOUN
dpc-2310	85	3	the	the	DET
dpc-2310	85	4	management	management	NOUN
dpc-2310	85	5	of	of	ADP
dpc-2310	85	6	ad	ad	NOUN
dpc-2310	85	7	with	with	ADP
dpc-2310	85	8	systemic	systemic	ADJ
dpc-2310	85	9	corticosteroids	corticosteroid	NOUN
dpc-2310	85	10	should	should	AUX
dpc-2310	85	11	generally	generally	ADV
dpc-2310	85	12	be	be	AUX
dpc-2310	85	13	avoided	avoid	VERB
dpc-2310	85	14	because	because	SCONJ
dpc-2310	85	15	of	of	ADP
dpc-2310	85	16	shortand	shortand	NOUN
dpc-2310	85	17	long	long	ADJ
dpc-2310	85	18	-	-	PUNCT
dpc-2310	85	19	term	term	NOUN
dpc-2310	85	20	adverse	adverse	ADJ
dpc-2310	85	21	effects	effect	NOUN
dpc-2310	85	22	.	.	PUNCT
dpc-2310	86	1	their	their	PRON
dpc-2310	86	2	use	use	NOUN
dpc-2310	86	3	should	should	AUX
dpc-2310	86	4	be	be	AUX
dpc-2310	86	5	exclusively	exclusively	ADV
dpc-2310	86	6	reserved	reserve	VERB
dpc-2310	86	7	for	for	ADP
dpc-2310	86	8	acute	acute	ADJ
dpc-2310	86	9	,	,	PUNCT
dpc-2310	86	10	severe	severe	ADJ
dpc-2310	86	11	exacerbations	exacerbation	NOUN
dpc-2310	86	12	and	and	CCONJ
dpc-2310	86	13	as	as	ADP
dpc-2310	86	14	a	a	DET
dpc-2310	86	15	short	short	ADJ
dpc-2310	86	16	-	-	PUNCT
dpc-2310	86	17	term	term	NOUN
dpc-2310	86	18	bridge	bridge	NOUN
dpc-2310	86	19	therapy	therapy	NOUN
dpc-2310	86	20	to	to	ADP
dpc-2310	86	21	other	other	ADJ
dpc-2310	86	22	systemic	systemic	ADJ
dpc-2310	86	23	,	,	PUNCT
dpc-2310	86	24	steroid	steroid	NOUN
dpc-2310	86	25	-	-	PUNCT
dpc-2310	86	26	sparing	spare	VERB
dpc-2310	86	27	therapy	therapy	NOUN
dpc-2310	86	28	[	[	X
dpc-2310	86	29	10	10	NUM
dpc-2310	86	30	]	]	PUNCT
dpc-2310	86	31	.	.	PUNCT
dpc-2310	87	1	cyclosporine	cyclosporine	PROPN
dpc-2310	87	2	cyclosporine	cyclosporine	PROPN
dpc-2310	87	3	(	(	PUNCT
dpc-2310	87	4	csa	csa	PROPN
dpc-2310	87	5	)	)	PUNCT
dpc-2310	87	6	is	be	AUX
dpc-2310	87	7	an	an	DET
dpc-2310	87	8	immunosuppressant	immunosuppressant	NOUN
dpc-2310	87	9	of	of	ADP
dpc-2310	87	10	t	t	PROPN
dpc-2310	87	11	-	-	PUNCT
dpc-2310	87	12	cells	cell	NOUN
dpc-2310	87	13	and	and	CCONJ
dpc-2310	87	14	interleukin-2	interleukin-2	NUM
dpc-2310	87	15	production	production	NOUN
dpc-2310	87	16	,	,	PUNCT
dpc-2310	87	17	used	use	VERB
dpc-2310	87	18	for	for	ADP
dpc-2310	87	19	adult	adult	NOUN
dpc-2310	87	20	and	and	CCONJ
dpc-2310	87	21	pediatric	pediatric	ADJ
dpc-2310	87	22	patients	patient	NOUN
dpc-2310	87	23	with	with	ADP
dpc-2310	87	24	severe	severe	ADJ
dpc-2310	87	25	or	or	CCONJ
dpc-2310	87	26	refractory	refractory	NOUN
dpc-2310	87	27	form	form	NOUN
dpc-2310	87	28	of	of	ADP
dpc-2310	87	29	ad	ad	NOUN
dpc-2310	87	30	.	.	PUNCT
dpc-2310	88	1	the	the	DET
dpc-2310	88	2	dosage	dosage	NOUN
dpc-2310	88	3	of	of	ADP
dpc-2310	88	4	csa	csa	PROPN
dpc-2310	88	5	(	(	PUNCT
dpc-2310	88	6	available	available	ADJ
dpc-2310	88	7	in	in	ADP
dpc-2310	88	8	oral	oral	ADJ
dpc-2310	88	9	capsules	capsule	NOUN
dpc-2310	88	10	and	and	CCONJ
dpc-2310	88	11	solution	solution	NOUN
dpc-2310	88	12	)	)	PUNCT
dpc-2310	88	13	ranges	range	VERB
dpc-2310	88	14	from	from	ADP
dpc-2310	88	15	3	3	NUM
dpc-2310	88	16	to	to	PART
dpc-2310	88	17	6	6	NUM
dpc-2310	88	18	mg	mg	PROPN
dpc-2310	88	19	/	/	SYM
dpc-2310	88	20	kg	kg	PROPN
dpc-2310	88	21	/	/	SYM
dpc-2310	88	22	d	d	PROPN
dpc-2310	88	23	,	,	PUNCT
dpc-2310	88	24	standardly	standardly	ADV
dpc-2310	88	25	150	150	NUM
dpc-2310	88	26	to	to	PART
dpc-2310	88	27	300	300	NUM
dpc-2310	88	28	mg/	mg/	ADJ
dpc-2310	88	29	day	day	NOUN
dpc-2310	88	30	in	in	ADP
dpc-2310	88	31	adults	adult	NOUN
dpc-2310	88	32	,	,	PUNCT
dpc-2310	88	33	divided	divide	VERB
dpc-2310	88	34	in	in	ADP
dpc-2310	88	35	two	two	NUM
dpc-2310	88	36	doses	dose	NOUN
dpc-2310	88	37	.	.	PUNCT
dpc-2310	89	1	the	the	DET
dpc-2310	89	2	initial	initial	ADJ
dpc-2310	89	3	and	and	CCONJ
dpc-2310	89	4	maintenance	maintenance	NOUN
dpc-2310	89	5	dose	dose	PROPN
dpc-2310	89	6	of	of	ADP
dpc-2310	89	7	csa	csa	PROPN
dpc-2310	89	8	should	should	AUX
dpc-2310	89	9	be	be	AUX
dpc-2310	89	10	based	base	VERB
dpc-2310	89	11	on	on	ADP
dpc-2310	89	12	multiple	multiple	ADJ
dpc-2310	89	13	factors	factor	NOUN
dpc-2310	89	14	,	,	PUNCT
dpc-2310	89	15	including	include	VERB
dpc-2310	89	16	the	the	DET
dpc-2310	89	17	patient	patient	NOUN
dpc-2310	89	18	’s	’s	PART
dpc-2310	89	19	disease	disease	NOUN
dpc-2310	89	20	severity	severity	NOUN
dpc-2310	89	21	and	and	CCONJ
dpc-2310	89	22	other	other	ADJ
dpc-2310	89	23	medical	medical	ADJ
dpc-2310	89	24	morbidities	morbidity	NOUN
dpc-2310	89	25	.	.	PUNCT
dpc-2310	90	1	potential	potential	ADJ
dpc-2310	90	2	adverse	adverse	ADJ
dpc-2310	90	3	effects	effect	NOUN
dpc-2310	90	4	include	include	VERB
dpc-2310	90	5	:	:	PUNCT
dpc-2310	90	6	hypertension	hypertension	NOUN
dpc-2310	90	7	,	,	PUNCT
dpc-2310	90	8	infection	infection	NOUN
dpc-2310	90	9	,	,	PUNCT
dpc-2310	90	10	nephrotoxicity	nephrotoxicity	NOUN
dpc-2310	90	11	,	,	PUNCT
dpc-2310	90	12	hypertension	hypertension	NOUN
dpc-2310	90	13	,	,	PUNCT
dpc-2310	90	14	tremor	tremor	NOUN
dpc-2310	90	15	,	,	PUNCT
dpc-2310	90	16	hypertrichosis	hypertrichosis	NOUN
dpc-2310	90	17	,	,	PUNCT
dpc-2310	90	18	headache	headache	NOUN
dpc-2310	90	19	,	,	PUNCT
dpc-2310	90	20	gingival	gingival	NOUN
dpc-2310	90	21	hyperplasia	hyperplasia	NOUN
dpc-2310	90	22	,	,	PUNCT
dpc-2310	90	23	and	and	CCONJ
dpc-2310	90	24	increased	increase	VERB
dpc-2310	90	25	risk	risk	NOUN
dpc-2310	90	26	of	of	ADP
dpc-2310	90	27	skin	skin	NOUN
dpc-2310	90	28	cancer	cancer	NOUN
dpc-2310	90	29	and	and	CCONJ
dpc-2310	90	30	lymphoma	lymphoma	NOUN
dpc-2310	90	31	.	.	PUNCT
dpc-2310	91	1	thus	thus	ADV
dpc-2310	91	2	,	,	PUNCT
dpc-2310	91	3	patients	patient	NOUN
dpc-2310	91	4	receiving	receive	VERB
dpc-2310	91	5	csa	csa	PROPN
dpc-2310	91	6	should	should	AUX
dpc-2310	91	7	be	be	AUX
dpc-2310	91	8	monitored	monitor	VERB
dpc-2310	91	9	for	for	ADP
dpc-2310	91	10	such	such	ADJ
dpc-2310	91	11	potential	potential	ADJ
dpc-2310	91	12	consequences	consequence	NOUN
dpc-2310	91	13	.	.	PUNCT
dpc-2310	92	1	the	the	DET
dpc-2310	92	2	recommended	recommend	VERB
dpc-2310	92	3	time	time	NOUN
dpc-2310	92	4	limit	limit	NOUN
dpc-2310	92	5	for	for	ADP
dpc-2310	92	6	consecutive	consecutive	ADJ
dpc-2310	92	7	use	use	NOUN
dpc-2310	92	8	of	of	ADP
dpc-2310	92	9	csa	csa	PROPN
dpc-2310	92	10	is	be	AUX
dpc-2310	92	11	currently	currently	ADV
dpc-2310	92	12	1	1	NUM
dpc-2310	92	13	year	year	NOUN
dpc-2310	92	14	.	.	PUNCT
dpc-2310	93	1	before	before	ADP
dpc-2310	93	2	starting	start	VERB
dpc-2310	93	3	therapy	therapy	NOUN
dpc-2310	93	4	,	,	PUNCT
dpc-2310	93	5	the	the	DET
dpc-2310	93	6	following	follow	VERB
dpc-2310	93	7	tests	test	NOUN
dpc-2310	93	8	should	should	AUX
dpc-2310	93	9	be	be	AUX
dpc-2310	93	10	prescribed	prescribe	VERB
dpc-2310	93	11	:	:	PUNCT
dpc-2310	93	12	blood	blood	NOUN
dpc-2310	93	13	count	count	NOUN
dpc-2310	93	14	,	,	PUNCT
dpc-2310	93	15	renal	renal	ADJ
dpc-2310	93	16	and	and	CCONJ
dpc-2310	93	17	liver	liver	NOUN
dpc-2310	93	18	function	function	NOUN
dpc-2310	93	19	,	,	PUNCT
dpc-2310	93	20	lipids	lipid	NOUN
dpc-2310	93	21	,	,	PUNCT
dpc-2310	93	22	electrolytes	electrolyte	NOUN
dpc-2310	93	23	,	,	PUNCT
dpc-2310	93	24	uric	uric	ADJ
dpc-2310	93	25	acid	acid	NOUN
dpc-2310	93	26	,	,	PUNCT
dpc-2310	93	27	hepatitis	hepatitis	PROPN
dpc-2310	93	28	b	b	PROPN
dpc-2310	93	29	and	and	CCONJ
dpc-2310	93	30	c	c	PROPN
dpc-2310	93	31	markers	marker	NOUN
dpc-2310	93	32	,	,	PUNCT
dpc-2310	93	33	hiv	hiv	PROPN
dpc-2310	93	34	and	and	CCONJ
dpc-2310	93	35	human	human	ADJ
dpc-2310	93	36	chorionic	chorionic	ADJ
dpc-2310	93	37	gonadotropin	gonadotropin	NOUN
dpc-2310	93	38	(	(	PUNCT
dpc-2310	93	39	hcg	hcg	PROPN
dpc-2310	93	40	)	)	PUNCT
dpc-2310	93	41	if	if	SCONJ
dpc-2310	93	42	indicated	indicate	VERB
dpc-2310	93	43	.	.	PUNCT
dpc-2310	94	1	during	during	ADP
dpc-2310	94	2	therapy	therapy	NOUN
dpc-2310	94	3	,	,	PUNCT
dpc-2310	94	4	blood	blood	NOUN
dpc-2310	94	5	pressure	pressure	NOUN
dpc-2310	94	6	should	should	AUX
dpc-2310	94	7	be	be	AUX
dpc-2310	94	8	measured	measure	VERB
dpc-2310	94	9	twice	twice	DET
dpc-2310	94	10	a	a	DET
dpc-2310	94	11	week	week	NOUN
dpc-2310	94	12	and	and	CCONJ
dpc-2310	94	13	blood	blood	NOUN
dpc-2310	94	14	tests	test	NOUN
dpc-2310	94	15	should	should	AUX
dpc-2310	94	16	be	be	AUX
dpc-2310	94	17	tested	test	VERB
dpc-2310	94	18	monthly	monthly	ADV
dpc-2310	94	19	[	[	X
dpc-2310	94	20	10	10	NUM
dpc-2310	94	21	]	]	PUNCT
dpc-2310	94	22	.	.	PUNCT
dpc-2310	95	1	csa	csa	PROPN
dpc-2310	95	2	can	can	AUX
dpc-2310	95	3	be	be	AUX
dpc-2310	95	4	associated	associate	VERB
dpc-2310	95	5	with	with	ADP
dpc-2310	95	6	dupilumab	dupilumab	NOUN
dpc-2310	95	7	in	in	ADP
dpc-2310	95	8	the	the	DET
dpc-2310	95	9	initial	initial	ADJ
dpc-2310	95	10	phase	phase	NOUN
dpc-2310	95	11	of	of	ADP
dpc-2310	95	12	therapy	therapy	NOUN
dpc-2310	95	13	to	to	PART
dpc-2310	95	14	induce	induce	VERB
dpc-2310	95	15	faster	fast	ADV
dpc-2310	95	16	the	the	DET
dpc-2310	95	17	clinical	clinical	ADJ
dpc-2310	95	18	remission	remission	NOUN
dpc-2310	95	19	or	or	CCONJ
dpc-2310	95	20	in	in	ADP
dpc-2310	95	21	patients	patient	NOUN
dpc-2310	95	22	recalcitrant	recalcitrant	ADJ
dpc-2310	95	23	to	to	PART
dpc-2310	95	24	dupilumab	dupilumab	VERB
dpc-2310	95	25	in	in	ADP
dpc-2310	95	26	monotherapy	monotherapy	NOUN
dpc-2310	95	27	[	[	X
dpc-2310	95	28	17	17	NUM
dpc-2310	95	29	]	]	SYM
dpc-2310	95	30	.	.	PUNCT
dpc-2310	96	1	4	4	NUM
dpc-2310	96	2	review	review	NOUN
dpc-2310	96	3	|	|	ADV
dpc-2310	96	4	dermatol	dermatol	ADJ
dpc-2310	96	5	pract	pract	NOUN
dpc-2310	96	6	concept	concept	NOUN
dpc-2310	96	7	.	.	PUNCT
dpc-2310	97	1	2022;12(1):e2022155	2022;12(1):e2022155	NUM
dpc-2310	97	2	individual	individual	PROPN
dpc-2310	97	3	’s	’s	PART
dpc-2310	97	4	thiopurine	thiopurine	NOUN
dpc-2310	97	5	s	s	NOUN
dpc-2310	97	6	-	-	NOUN
dpc-2310	97	7	methyltransferase	methyltransferase	NOUN
dpc-2310	97	8	(	(	PUNCT
dpc-2310	97	9	tpmt	tpmt	NOUN
dpc-2310	97	10	)	)	PUNCT
dpc-2310	97	11	activity	activity	NOUN
dpc-2310	97	12	level	level	NOUN
dpc-2310	97	13	,	,	PUNCT
dpc-2310	97	14	a	a	DET
dpc-2310	97	15	principal	principal	ADJ
dpc-2310	97	16	enzyme	enzyme	NOUN
dpc-2310	97	17	in	in	ADP
dpc-2310	97	18	the	the	DET
dpc-2310	97	19	thiopurine	thiopurine	NOUN
dpc-2310	97	20	pathway	pathway	NOUN
dpc-2310	97	21	.	.	PUNCT
dpc-2310	98	1	genetic	genetic	ADJ
dpc-2310	98	2	polymorphisms	polymorphism	NOUN
dpc-2310	98	3	in	in	ADP
dpc-2310	98	4	tpmt	tpmt	NOUN
dpc-2310	98	5	activity	activity	NOUN
dpc-2310	98	6	are	be	AUX
dpc-2310	98	7	linked	link	VERB
dpc-2310	98	8	to	to	ADP
dpc-2310	98	9	a	a	DET
dpc-2310	98	10	patient	patient	NOUN
dpc-2310	98	11	’s	’s	PART
dpc-2310	98	12	susceptibility	susceptibility	NOUN
dpc-2310	98	13	to	to	ADP
dpc-2310	98	14	aza	aza	NOUN
dpc-2310	98	15	toxicity	toxicity	NOUN
dpc-2310	98	16	,	,	PUNCT
dpc-2310	98	17	such	such	ADJ
dpc-2310	98	18	that	that	SCONJ
dpc-2310	98	19	the	the	DET
dpc-2310	98	20	homozygous	homozygous	ADJ
dpc-2310	98	21	carrier	carrier	NOUN
dpc-2310	98	22	state	state	NOUN
dpc-2310	98	23	of	of	ADP
dpc-2310	98	24	low	low	ADJ
dpc-2310	98	25	or	or	CCONJ
dpc-2310	98	26	absent	absent	ADJ
dpc-2310	98	27	enzyme	enzyme	NOUN
dpc-2310	98	28	capacity	capacity	NOUN
dpc-2310	98	29	poses	pose	VERB
dpc-2310	98	30	the	the	DET
dpc-2310	98	31	greatest	great	ADJ
dpc-2310	98	32	toxicity	toxicity	NOUN
dpc-2310	98	33	risk	risk	NOUN
dpc-2310	98	34	.	.	PUNCT
dpc-2310	99	1	thus	thus	ADV
dpc-2310	99	2	,	,	PUNCT
dpc-2310	99	3	baseline	baseline	ADJ
dpc-2310	99	4	tpmt	tpmt	NOUN
dpc-2310	99	5	level	level	NOUN
dpc-2310	99	6	testing	testing	NOUN
dpc-2310	99	7	is	be	AUX
dpc-2310	99	8	strongly	strongly	ADV
dpc-2310	99	9	recommended	recommend	VERB
dpc-2310	99	10	before	before	ADP
dpc-2310	99	11	aza	aza	NOUN
dpc-2310	99	12	initiation	initiation	NOUN
dpc-2310	99	13	,	,	PUNCT
dpc-2310	99	14	with	with	ADP
dpc-2310	99	15	avoidance	avoidance	NOUN
dpc-2310	99	16	of	of	ADP
dpc-2310	99	17	use	use	NOUN
dpc-2310	99	18	in	in	ADP
dpc-2310	99	19	those	those	PRON
dpc-2310	99	20	with	with	ADP
dpc-2310	99	21	very	very	ADV
dpc-2310	99	22	low	low	ADJ
dpc-2310	99	23	or	or	CCONJ
dpc-2310	99	24	absent	absent	ADJ
dpc-2310	99	25	enzyme	enzyme	NOUN
dpc-2310	99	26	activity	activity	NOUN
dpc-2310	99	27	.	.	PUNCT
dpc-2310	100	1	concomitant	concomitant	ADJ
dpc-2310	100	2	phototherapy	phototherapy	NOUN
dpc-2310	100	3	is	be	AUX
dpc-2310	100	4	not	not	PART
dpc-2310	100	5	advised	advise	VERB
dpc-2310	100	6	because	because	SCONJ
dpc-2310	100	7	of	of	ADP
dpc-2310	100	8	increased	increase	VERB
dpc-2310	100	9	risk	risk	NOUN
dpc-2310	100	10	of	of	ADP
dpc-2310	100	11	dna	dna	PROPN
dpc-2310	100	12	damage	damage	NOUN
dpc-2310	100	13	and	and	CCONJ
dpc-2310	100	14	possible	possible	ADJ
dpc-2310	100	15	photocarcinogenicity	photocarcinogenicity	NOUN
dpc-2310	100	16	.	.	PUNCT
dpc-2310	101	1	nausea	nausea	NOUN
dpc-2310	101	2	,	,	PUNCT
dpc-2310	101	3	vomiting	vomiting	NOUN
dpc-2310	101	4	and	and	CCONJ
dpc-2310	101	5	other	other	ADJ
dpc-2310	101	6	gastrointestinal	gastrointestinal	ADJ
dpc-2310	101	7	symptoms	symptom	NOUN
dpc-2310	101	8	(	(	PUNCT
dpc-2310	101	9	bloating	bloat	VERB
dpc-2310	101	10	,	,	PUNCT
dpc-2310	101	11	anorexia	anorexia	ADJ
dpc-2310	101	12	,	,	PUNCT
dpc-2310	101	13	cramping	cramping	NOUN
dpc-2310	101	14	)	)	PUNCT
dpc-2310	101	15	are	be	AUX
dpc-2310	101	16	common	common	ADJ
dpc-2310	101	17	adverse	adverse	ADJ
dpc-2310	101	18	effects	effect	NOUN
dpc-2310	101	19	.	.	PUNCT
dpc-2310	102	1	other	other	ADJ
dpc-2310	102	2	side	side	NOUN
dpc-2310	102	3	effects	effect	NOUN
dpc-2310	102	4	include	include	VERB
dpc-2310	102	5	headache	headache	NOUN
dpc-2310	102	6	,	,	PUNCT
dpc-2310	102	7	hypersensitivity	hypersensitivity	NOUN
dpc-2310	102	8	reactions	reaction	NOUN
dpc-2310	102	9	,	,	PUNCT
dpc-2310	102	10	elevated	elevated	ADJ
dpc-2310	102	11	liver	liver	NOUN
dpc-2310	102	12	enzymes	enzyme	NOUN
dpc-2310	102	13	,	,	PUNCT
dpc-2310	102	14	and	and	CCONJ
dpc-2310	102	15	leukopenia	leukopenia	PROPN
dpc-2310	102	16	.	.	PUNCT
dpc-2310	103	1	aza	aza	NOUN
dpc-2310	103	2	can	can	AUX
dpc-2310	103	3	be	be	AUX
dpc-2310	103	4	used	use	VERB
dpc-2310	103	5	for	for	ADP
dpc-2310	103	6	pediatric	pediatric	ADJ
dpc-2310	103	7	population	population	NOUN
dpc-2310	103	8	in	in	ADP
dpc-2310	103	9	case	case	NOUN
dpc-2310	103	10	of	of	ADP
dpc-2310	103	11	recalcitrant	recalcitrant	ADJ
dpc-2310	103	12	dermatitis	dermatitis	NOUN
dpc-2310	103	13	but	but	CCONJ
dpc-2310	103	14	there	there	PRON
dpc-2310	103	15	are	be	VERB
dpc-2310	103	16	not	not	PART
dpc-2310	103	17	sufficient	sufficient	ADJ
dpc-2310	103	18	data	datum	NOUN
dpc-2310	103	19	to	to	PART
dpc-2310	103	20	recommend	recommend	VERB
dpc-2310	103	21	an	an	DET
dpc-2310	103	22	optimal	optimal	ADJ
dpc-2310	103	23	dose	dose	NOUN
dpc-2310	103	24	,	,	PUNCT
dpc-2310	103	25	duration	duration	NOUN
dpc-2310	103	26	of	of	ADP
dpc-2310	103	27	therapy	therapy	NOUN
dpc-2310	103	28	,	,	PUNCT
dpc-2310	103	29	or	or	CCONJ
dpc-2310	103	30	to	to	PART
dpc-2310	103	31	predict	predict	VERB
dpc-2310	103	32	the	the	DET
dpc-2310	103	33	relapse	relapse	NOUN
dpc-2310	103	34	rate	rate	NOUN
dpc-2310	103	35	upon	upon	SCONJ
dpc-2310	103	36	discontinuation	discontinuation	NOUN
dpc-2310	103	37	.	.	PUNCT
dpc-2310	104	1	however	however	ADV
dpc-2310	104	2	,	,	PUNCT
dpc-2310	104	3	the	the	DET
dpc-2310	104	4	most	most	ADV
dpc-2310	104	5	common	common	ADJ
dpc-2310	104	6	dosage	dosage	NOUN
dpc-2310	104	7	given	give	VERB
dpc-2310	104	8	is	be	AUX
dpc-2310	104	9	2.5	2.5	NUM
dpc-2310	104	10	mg	mg	NUM
dpc-2310	104	11	/	/	SYM
dpc-2310	104	12	kg	kg	PROPN
dpc-2310	104	13	/	/	SYM
dpc-2310	104	14	d	d	PROPN
dpc-2310	104	15	,	,	PUNCT
dpc-2310	104	16	with	with	ADP
dpc-2310	104	17	a	a	DET
dpc-2310	104	18	higher	high	ADJ
dpc-2310	104	19	treatment	treatment	NOUN
dpc-2310	104	20	range	range	NOUN
dpc-2310	104	21	maximum	maximum	NOUN
dpc-2310	104	22	of	of	ADP
dpc-2310	104	23	4	4	NUM
dpc-2310	104	24	mg	mg	NUM
dpc-2310	104	25	/	/	SYM
dpc-2310	104	26	kg	kg	NOUN
dpc-2310	104	27	/	/	SYM
dpc-2310	104	28	d	d	NOUN
dpc-2310	104	29	relative	relative	ADJ
dpc-2310	104	30	to	to	ADP
dpc-2310	104	31	adult	adult	VERB
dpc-2310	104	32	dosing	dosing	NOUN
dpc-2310	104	33	(	(	PUNCT
dpc-2310	104	34	maximum	maximum	ADJ
dpc-2310	104	35	3	3	NUM
dpc-2310	104	36	mg	mg	PROPN
dpc-2310	104	37	/	/	SYM
dpc-2310	104	38	kg	kg	PROPN
dpc-2310	104	39	/	/	SYM
dpc-2310	104	40	d	d	NOUN
dpc-2310	104	41	)	)	PUNCT
dpc-2310	105	1	[	[	X
dpc-2310	105	2	10	10	NUM
dpc-2310	105	3	]	]	PUNCT
dpc-2310	105	4	.	.	PUNCT
dpc-2310	106	1	mycophenolate	mycophenolate	PROPN
dpc-2310	106	2	mofetil	mofetil	PROPN
dpc-2310	106	3	mycophenolate	mycophenolate	PROPN
dpc-2310	106	4	mofetil	mofetil	PROPN
dpc-2310	106	5	(	(	PUNCT
dpc-2310	106	6	mmf	mmf	NOUN
dpc-2310	106	7	)	)	PUNCT
dpc-2310	106	8	is	be	AUX
dpc-2310	106	9	an	an	DET
dpc-2310	106	10	immunosuppressant	immunosuppressant	NOUN
dpc-2310	106	11	that	that	PRON
dpc-2310	106	12	blocks	block	VERB
dpc-2310	106	13	the	the	DET
dpc-2310	106	14	purine	purine	NOUN
dpc-2310	106	15	biosynthesis	biosynthesis	NOUN
dpc-2310	106	16	pathway	pathway	NOUN
dpc-2310	106	17	of	of	ADP
dpc-2310	106	18	cells	cell	NOUN
dpc-2310	106	19	via	via	ADP
dpc-2310	106	20	the	the	DET
dpc-2310	106	21	inhibition	inhibition	NOUN
dpc-2310	106	22	of	of	ADP
dpc-2310	106	23	inosine	inosine	NOUN
dpc-2310	106	24	monophosphate	monophosphate	NOUN
dpc-2310	106	25	dehydrogenase	dehydrogenase	NOUN
dpc-2310	106	26	,	,	PUNCT
dpc-2310	106	27	selectively	selectively	ADV
dpc-2310	106	28	affecting	affect	VERB
dpc-2310	106	29	band	band	NOUN
dpc-2310	106	30	t	t	PROPN
dpc-2310	106	31	-	-	PUNCT
dpc-2310	106	32	cells	cell	NOUN
dpc-2310	106	33	.	.	PUNCT
dpc-2310	107	1	it	it	PRON
dpc-2310	107	2	is	be	AUX
dpc-2310	107	3	recognized	recognize	VERB
dpc-2310	107	4	as	as	ADP
dpc-2310	107	5	an	an	DET
dpc-2310	107	6	off	off	ADP
dpc-2310	107	7	-	-	PUNCT
dpc-2310	107	8	label	label	NOUN
dpc-2310	107	9	therapy	therapy	NOUN
dpc-2310	107	10	in	in	ADP
dpc-2310	107	11	patients	patient	NOUN
dpc-2310	107	12	with	with	ADP
dpc-2310	107	13	refractory	refractory	NOUN
dpc-2310	107	14	forms	form	NOUN
dpc-2310	107	15	of	of	ADP
dpc-2310	107	16	ad	ad	NOUN
dpc-2310	107	17	.	.	PUNCT
dpc-2310	108	1	insufficient	insufficient	ADJ
dpc-2310	108	2	data	datum	NOUN
dpc-2310	108	3	exist	exist	VERB
dpc-2310	108	4	to	to	PART
dpc-2310	108	5	make	make	VERB
dpc-2310	108	6	recommendations	recommendation	NOUN
dpc-2310	108	7	regarding	regard	VERB
dpc-2310	108	8	the	the	DET
dpc-2310	108	9	optimal	optimal	ADJ
dpc-2310	108	10	mmf	mmf	NOUN
dpc-2310	108	11	dosing	dosing	NOUN
dpc-2310	108	12	or	or	CCONJ
dpc-2310	108	13	duration	duration	NOUN
dpc-2310	108	14	of	of	ADP
dpc-2310	108	15	therapy	therapy	NOUN
dpc-2310	108	16	for	for	ADP
dpc-2310	108	17	patients	patient	NOUN
dpc-2310	108	18	with	with	ADP
dpc-2310	108	19	ad	ad	NOUN
dpc-2310	108	20	.	.	PUNCT
dpc-2310	109	1	dosing	dose	VERB
dpc-2310	109	2	ranges	range	NOUN
dpc-2310	109	3	from	from	ADP
dpc-2310	109	4	0.5	0.5	NUM
dpc-2310	109	5	to	to	ADP
dpc-2310	109	6	3	3	NUM
dpc-2310	109	7	g	g	NOUN
dpc-2310	109	8	/	/	SYM
dpc-2310	109	9	d.	d.	PROPN
dpc-2310	109	10	mmf	mmf	NOUN
dpc-2310	109	11	is	be	AUX
dpc-2310	109	12	available	available	ADJ
dpc-2310	109	13	in	in	ADP
dpc-2310	109	14	oral	oral	ADJ
dpc-2310	109	15	suspension	suspension	NOUN
dpc-2310	109	16	,	,	PUNCT
dpc-2310	109	17	capsules	capsule	NOUN
dpc-2310	109	18	,	,	PUNCT
dpc-2310	109	19	and	and	CCONJ
dpc-2310	109	20	tablets	tablet	NOUN
dpc-2310	109	21	,	,	PUNCT
dpc-2310	109	22	and	and	CCONJ
dpc-2310	109	23	it	it	PRON
dpc-2310	109	24	is	be	AUX
dpc-2310	109	25	given	give	VERB
dpc-2310	109	26	twice	twice	ADV
dpc-2310	109	27	daily	daily	ADV
dpc-2310	109	28	.	.	PUNCT
dpc-2310	110	1	mmf	mmf	NOUN
dpc-2310	110	2	is	be	AUX
dpc-2310	110	3	generally	generally	ADV
dpc-2310	110	4	well	well	ADV
dpc-2310	110	5	tolerated	tolerate	VERB
dpc-2310	110	6	,	,	PUNCT
dpc-2310	110	7	with	with	ADP
dpc-2310	110	8	nausea	nausea	NOUN
dpc-2310	110	9	,	,	PUNCT
dpc-2310	110	10	vomiting	vomiting	NOUN
dpc-2310	110	11	,	,	PUNCT
dpc-2310	110	12	and	and	CCONJ
dpc-2310	110	13	abdominal	abdominal	ADJ
dpc-2310	110	14	cramping	cramping	NOUN
dpc-2310	110	15	being	be	AUX
dpc-2310	110	16	the	the	DET
dpc-2310	110	17	most	most	ADV
dpc-2310	110	18	common	common	ADJ
dpc-2310	110	19	side	side	NOUN
dpc-2310	110	20	effects	effect	NOUN
dpc-2310	110	21	.	.	PUNCT
dpc-2310	111	1	rarely	rarely	ADV
dpc-2310	111	2	,	,	PUNCT
dpc-2310	111	3	hematologic	hematologic	NOUN
dpc-2310	111	4	(	(	PUNCT
dpc-2310	111	5	anemia	anemia	NOUN
dpc-2310	111	6	,	,	PUNCT
dpc-2310	111	7	leukopenia	leukopenia	PROPN
dpc-2310	111	8	,	,	PUNCT
dpc-2310	111	9	thrombocytopenia	thrombocytopenia	PROPN
dpc-2310	111	10	)	)	PUNCT
dpc-2310	111	11	and	and	CCONJ
dpc-2310	111	12	genitourinary	genitourinary	ADJ
dpc-2310	111	13	(	(	PUNCT
dpc-2310	111	14	urgency	urgency	NOUN
dpc-2310	111	15	,	,	PUNCT
dpc-2310	111	16	frequency	frequency	NOUN
dpc-2310	111	17	,	,	PUNCT
dpc-2310	111	18	dysuria	dysuria	ADJ
dpc-2310	111	19	)	)	PUNCT
dpc-2310	111	20	toxicities	toxicity	NOUN
dpc-2310	111	21	have	have	AUX
dpc-2310	111	22	been	be	AUX
dpc-2310	111	23	reported	report	VERB
dpc-2310	111	24	.	.	PUNCT
dpc-2310	112	1	there	there	PRON
dpc-2310	112	2	is	be	VERB
dpc-2310	112	3	a	a	DET
dpc-2310	112	4	theoretical	theoretical	ADJ
dpc-2310	112	5	risk	risk	NOUN
dpc-2310	112	6	of	of	ADP
dpc-2310	112	7	increased	increase	VERB
dpc-2310	112	8	susceptibility	susceptibility	NOUN
dpc-2310	112	9	to	to	ADP
dpc-2310	112	10	viral	viral	ADJ
dpc-2310	112	11	and	and	CCONJ
dpc-2310	112	12	bacterial	bacterial	ADJ
dpc-2310	112	13	infections	infection	NOUN
dpc-2310	112	14	while	while	SCONJ
dpc-2310	112	15	taking	take	VERB
dpc-2310	112	16	mmf	mmf	NOUN
dpc-2310	112	17	,	,	PUNCT
dpc-2310	112	18	as	as	SCONJ
dpc-2310	112	19	it	it	PRON
dpc-2310	112	20	is	be	AUX
dpc-2310	112	21	clearly	clearly	ADV
dpc-2310	112	22	observed	observe	VERB
dpc-2310	112	23	in	in	ADP
dpc-2310	112	24	patients	patient	NOUN
dpc-2310	112	25	with	with	ADP
dpc-2310	112	26	organ	organ	NOUN
dpc-2310	112	27	transplantation	transplantation	NOUN
dpc-2310	112	28	.	.	PUNCT
dpc-2310	113	1	cutaneous	cutaneous	ADJ
dpc-2310	113	2	malignancy	malignancy	NOUN
dpc-2310	113	3	and	and	CCONJ
dpc-2310	113	4	lymphoma	lymphoma	NOUN
dpc-2310	113	5	are	be	AUX
dpc-2310	113	6	potential	potential	ADJ
dpc-2310	113	7	risks	risk	NOUN
dpc-2310	113	8	[	[	X
dpc-2310	113	9	10	10	NUM
dpc-2310	113	10	]	]	PUNCT
dpc-2310	113	11	.	.	PUNCT
dpc-2310	114	1	conclusions	conclusion	NOUN
dpc-2310	114	2	the	the	DET
dpc-2310	114	3	introduction	introduction	NOUN
dpc-2310	114	4	of	of	ADP
dpc-2310	114	5	dupilumab	dupilumab	NOUN
dpc-2310	114	6	has	have	AUX
dpc-2310	114	7	changed	change	VERB
dpc-2310	114	8	the	the	DET
dpc-2310	114	9	management	management	NOUN
dpc-2310	114	10	of	of	ADP
dpc-2310	114	11	patients	patient	NOUN
dpc-2310	114	12	with	with	ADP
dpc-2310	114	13	severe	severe	ADJ
dpc-2310	114	14	forms	form	NOUN
dpc-2310	114	15	of	of	ADP
dpc-2310	114	16	ad	ad	NOUN
dpc-2310	114	17	but	but	CCONJ
dpc-2310	114	18	traditional	traditional	ADJ
dpc-2310	114	19	drugs	drug	NOUN
dpc-2310	114	20	remain	remain	VERB
dpc-2310	114	21	a	a	DET
dpc-2310	114	22	milestone	milestone	NOUN
dpc-2310	114	23	for	for	ADP
dpc-2310	114	24	the	the	DET
dpc-2310	114	25	treatment	treatment	NOUN
dpc-2310	114	26	of	of	ADP
dpc-2310	114	27	mild	mild	ADJ
dpc-2310	114	28	-	-	PUNCT
dpc-2310	114	29	moderate	moderate	ADJ
dpc-2310	114	30	ad	ad	NOUN
dpc-2310	114	31	and	and	CCONJ
dpc-2310	114	32	for	for	ADP
dpc-2310	114	33	combined	combined	ADJ
dpc-2310	114	34	therapies	therapy	NOUN
dpc-2310	114	35	.	.	PUNCT
dpc-2310	115	1	therefore	therefore	ADV
dpc-2310	115	2	,	,	PUNCT
dpc-2310	115	3	dermatologists	dermatologist	NOUN
dpc-2310	115	4	need	need	VERB
dpc-2310	115	5	a	a	DET
dpc-2310	115	6	good	good	ADJ
dpc-2310	115	7	knowledge	knowledge	NOUN
dpc-2310	115	8	of	of	ADP
dpc-2310	115	9	both	both	DET
dpc-2310	115	10	fields	field	NOUN
dpc-2310	115	11	of	of	ADP
dpc-2310	115	12	interest	interest	NOUN
dpc-2310	115	13	for	for	ADP
dpc-2310	115	14	an	an	DET
dpc-2310	115	15	integrated	integrate	VERB
dpc-2310	115	16	and	and	CCONJ
dpc-2310	115	17	personalized	personalized	ADJ
dpc-2310	115	18	management	management	NOUN
dpc-2310	115	19	of	of	ADP
dpc-2310	115	20	patients	patient	NOUN
dpc-2310	115	21	.	.	PUNCT
dpc-2310	116	1	methotrexate	methotrexate	PROPN
dpc-2310	116	2	methotrexate	methotrexate	PROPN
dpc-2310	116	3	(	(	PUNCT
dpc-2310	116	4	mtx	mtx	NOUN
dpc-2310	116	5	)	)	PUNCT
dpc-2310	116	6	is	be	AUX
dpc-2310	116	7	an	an	DET
dpc-2310	116	8	antifolate	antifolate	NOUN
dpc-2310	116	9	metabolite	metabolite	NOUN
dpc-2310	116	10	and	and	CCONJ
dpc-2310	116	11	blocks	block	VERB
dpc-2310	116	12	the	the	DET
dpc-2310	116	13	synthesis	synthesis	NOUN
dpc-2310	116	14	of	of	ADP
dpc-2310	116	15	dna	dna	PROPN
dpc-2310	116	16	,	,	PUNCT
dpc-2310	116	17	rna	rna	NOUN
dpc-2310	116	18	,	,	PUNCT
dpc-2310	116	19	and	and	CCONJ
dpc-2310	116	20	purines	purine	NOUN
dpc-2310	116	21	.	.	PUNCT
dpc-2310	117	1	it	it	PRON
dpc-2310	117	2	is	be	AUX
dpc-2310	117	3	also	also	ADV
dpc-2310	117	4	thought	think	VERB
dpc-2310	117	5	to	to	PART
dpc-2310	117	6	negatively	negatively	ADV
dpc-2310	117	7	affect	affect	VERB
dpc-2310	117	8	t	t	NOUN
dpc-2310	117	9	-	-	PUNCT
dpc-2310	117	10	cell	cell	NOUN
dpc-2310	117	11	function	function	NOUN
dpc-2310	117	12	.	.	PUNCT
dpc-2310	118	1	its	its	PRON
dpc-2310	118	2	many	many	ADJ
dpc-2310	118	3	off	off	ADP
dpc-2310	118	4	-	-	PUNCT
dpc-2310	118	5	label	label	NOUN
dpc-2310	118	6	uses	use	NOUN
dpc-2310	118	7	include	include	VERB
dpc-2310	118	8	treatment	treatment	NOUN
dpc-2310	118	9	of	of	ADP
dpc-2310	118	10	refractory	refractory	NOUN
dpc-2310	118	11	ad	ad	NOUN
dpc-2310	118	12	.	.	PUNCT
dpc-2310	119	1	mtx	mtx	NOUN
dpc-2310	119	2	is	be	AUX
dpc-2310	119	3	available	available	ADJ
dpc-2310	119	4	in	in	ADP
dpc-2310	119	5	solution	solution	NOUN
dpc-2310	119	6	(	(	PUNCT
dpc-2310	119	7	for	for	ADP
dpc-2310	119	8	intramuscular	intramuscular	ADJ
dpc-2310	119	9	or	or	CCONJ
dpc-2310	119	10	subcutaneous	subcutaneous	ADJ
dpc-2310	119	11	injection	injection	NOUN
dpc-2310	119	12	)	)	PUNCT
dpc-2310	119	13	and	and	CCONJ
dpc-2310	119	14	oral	oral	ADJ
dpc-2310	119	15	tablet	tablet	NOUN
dpc-2310	119	16	form	form	NOUN
dpc-2310	119	17	.	.	PUNCT
dpc-2310	120	1	mtx	mtx	NOUN
dpc-2310	120	2	is	be	AUX
dpc-2310	120	3	usually	usually	ADV
dpc-2310	120	4	given	give	VERB
dpc-2310	120	5	as	as	ADP
dpc-2310	120	6	a	a	DET
dpc-2310	120	7	single	single	ADJ
dpc-2310	120	8	weekly	weekly	ADJ
dpc-2310	120	9	dose	dose	NOUN
dpc-2310	120	10	.	.	PUNCT
dpc-2310	121	1	the	the	DET
dpc-2310	121	2	dose	dose	NOUN
dpc-2310	121	3	range	range	NOUN
dpc-2310	121	4	for	for	ADP
dpc-2310	121	5	mtx	mtx	NOUN
dpc-2310	121	6	in	in	ADP
dpc-2310	121	7	patients	patient	NOUN
dpc-2310	121	8	with	with	ADP
dpc-2310	121	9	ad	ad	NOUN
dpc-2310	121	10	is	be	AUX
dpc-2310	121	11	extrapolated	extrapolate	VERB
dpc-2310	121	12	from	from	ADP
dpc-2310	121	13	its	its	PRON
dpc-2310	121	14	use	use	NOUN
dpc-2310	121	15	in	in	ADP
dpc-2310	121	16	psoriasis	psoriasis	NOUN
dpc-2310	121	17	and	and	CCONJ
dpc-2310	121	18	it	it	PRON
dpc-2310	121	19	is	be	AUX
dpc-2310	121	20	between	between	ADP
dpc-2310	121	21	7.5	7.5	NUM
dpc-2310	121	22	and	and	CCONJ
dpc-2310	121	23	25	25	NUM
dpc-2310	121	24	mg	mg	NOUN
dpc-2310	121	25	weekly	weekly	ADJ
dpc-2310	121	26	.	.	PUNCT
dpc-2310	122	1	folate	folate	NOUN
dpc-2310	122	2	supplementation	supplementation	NOUN
dpc-2310	122	3	is	be	AUX
dpc-2310	122	4	recommended	recommend	VERB
dpc-2310	122	5	during	during	ADP
dpc-2310	122	6	treatment	treatment	NOUN
dpc-2310	122	7	with	with	ADP
dpc-2310	122	8	mtx	mtx	NOUN
dpc-2310	122	9	.	.	PROPN
dpc-2310	122	10	nausea	nausea	NOUN
dpc-2310	122	11	and	and	CCONJ
dpc-2310	122	12	other	other	ADJ
dpc-2310	122	13	gastrointestinal	gastrointestinal	ADJ
dpc-2310	122	14	symptoms	symptom	NOUN
dpc-2310	122	15	may	may	AUX
dpc-2310	122	16	preclude	preclude	VERB
dpc-2310	122	17	oral	oral	ADJ
dpc-2310	122	18	administration	administration	NOUN
dpc-2310	122	19	.	.	PUNCT
dpc-2310	123	1	severe	severe	ADJ
dpc-2310	123	2	adverse	adverse	ADJ
dpc-2310	123	3	effects	effect	NOUN
dpc-2310	123	4	,	,	PUNCT
dpc-2310	123	5	including	include	VERB
dpc-2310	123	6	bone	bone	NOUN
dpc-2310	123	7	-	-	PUNCT
dpc-2310	123	8	marrow	marrow	NOUN
dpc-2310	123	9	suppression	suppression	NOUN
dpc-2310	123	10	and	and	CCONJ
dpc-2310	123	11	pulmonary	pulmonary	ADJ
dpc-2310	123	12	fibrosis	fibrosis	NOUN
dpc-2310	123	13	,	,	PUNCT
dpc-2310	123	14	can	can	AUX
dpc-2310	123	15	occur	occur	VERB
dpc-2310	123	16	.	.	PUNCT
dpc-2310	124	1	literature	literature	NOUN
dpc-2310	124	2	suggests	suggest	VERB
dpc-2310	124	3	that	that	SCONJ
dpc-2310	124	4	bone	bone	NOUN
dpc-2310	124	5	-	-	PUNCT
dpc-2310	124	6	marrow	marrow	NOUN
dpc-2310	124	7	suppression	suppression	NOUN
dpc-2310	124	8	is	be	AUX
dpc-2310	124	9	often	often	ADV
dpc-2310	124	10	reversible	reversible	ADJ
dpc-2310	124	11	upon	upon	SCONJ
dpc-2310	124	12	mtx	mtx	NOUN
dpc-2310	124	13	dose	dose	NOUN
dpc-2310	124	14	reduction	reduction	NOUN
dpc-2310	124	15	or	or	CCONJ
dpc-2310	124	16	discontinuation	discontinuation	NOUN
dpc-2310	124	17	.	.	PUNCT
dpc-2310	125	1	risk	risk	NOUN
dpc-2310	125	2	for	for	ADP
dpc-2310	125	3	skin	skin	NOUN
dpc-2310	125	4	cancer	cancer	NOUN
dpc-2310	125	5	and	and	CCONJ
dpc-2310	125	6	lymphoma	lymphoma	NOUN
dpc-2310	125	7	has	have	AUX
dpc-2310	125	8	been	be	AUX
dpc-2310	125	9	reported	report	VERB
dpc-2310	125	10	,	,	PUNCT
dpc-2310	125	11	although	although	SCONJ
dpc-2310	125	12	some	some	DET
dpc-2310	125	13	cases	case	NOUN
dpc-2310	125	14	of	of	ADP
dpc-2310	125	15	lymphoma	lymphoma	NOUN
dpc-2310	125	16	arising	arise	VERB
dpc-2310	125	17	during	during	ADP
dpc-2310	125	18	low	low	ADJ
dpc-2310	125	19	-	-	PUNCT
dpc-2310	125	20	dose	dose	NOUN
dpc-2310	125	21	treatment	treatment	NOUN
dpc-2310	125	22	have	have	AUX
dpc-2310	125	23	regressed	regress	VERB
dpc-2310	125	24	on	on	ADP
dpc-2310	125	25	drug	drug	NOUN
dpc-2310	125	26	discontinuation	discontinuation	NOUN
dpc-2310	125	27	.	.	PUNCT
dpc-2310	126	1	pulmonary	pulmonary	ADJ
dpc-2310	126	2	fibrosis	fibrosis	NOUN
dpc-2310	126	3	may	may	AUX
dpc-2310	126	4	occur	occur	VERB
dpc-2310	126	5	with	with	ADP
dpc-2310	126	6	shortor	shortor	NOUN
dpc-2310	126	7	long	long	ADJ
dpc-2310	126	8	-	-	PUNCT
dpc-2310	126	9	term	term	NOUN
dpc-2310	126	10	use	use	NOUN
dpc-2310	126	11	of	of	ADP
dpc-2310	126	12	the	the	DET
dpc-2310	126	13	medication	medication	NOUN
dpc-2310	126	14	,	,	PUNCT
dpc-2310	126	15	such	such	ADJ
dpc-2310	126	16	that	that	SCONJ
dpc-2310	126	17	patients	patient	NOUN
dpc-2310	126	18	with	with	ADP
dpc-2310	126	19	pulmonary	pulmonary	ADJ
dpc-2310	126	20	diseases	disease	NOUN
dpc-2310	126	21	(	(	PUNCT
dpc-2310	126	22	eg	eg	NOUN
dpc-2310	126	23	asthma	asthma	NOUN
dpc-2310	126	24	,	,	PUNCT
dpc-2310	126	25	chronic	chronic	ADJ
dpc-2310	126	26	cough	cough	NOUN
dpc-2310	126	27	)	)	PUNCT
dpc-2310	126	28	may	may	AUX
dpc-2310	126	29	not	not	PART
dpc-2310	126	30	be	be	AUX
dpc-2310	126	31	candidates	candidate	NOUN
dpc-2310	126	32	.	.	PUNCT
dpc-2310	127	1	before	before	ADP
dpc-2310	127	2	starting	start	VERB
dpc-2310	127	3	therapy	therapy	NOUN
dpc-2310	127	4	,	,	PUNCT
dpc-2310	127	5	the	the	DET
dpc-2310	127	6	following	follow	VERB
dpc-2310	127	7	tests	test	NOUN
dpc-2310	127	8	should	should	AUX
dpc-2310	127	9	be	be	AUX
dpc-2310	127	10	prescribed	prescribe	VERB
dpc-2310	127	11	:	:	PUNCT
dpc-2310	127	12	blood	blood	NOUN
dpc-2310	127	13	count	count	NOUN
dpc-2310	127	14	,	,	PUNCT
dpc-2310	127	15	renal	renal	ADJ
dpc-2310	127	16	and	and	CCONJ
dpc-2310	127	17	liver	liver	NOUN
dpc-2310	127	18	function	function	NOUN
dpc-2310	127	19	,	,	PUNCT
dpc-2310	127	20	lipids	lipid	NOUN
dpc-2310	127	21	,	,	PUNCT
dpc-2310	127	22	electrolyte	electrolyte	ADJ
dpc-2310	127	23	,	,	PUNCT
dpc-2310	127	24	uric	uric	ADJ
dpc-2310	127	25	acid	acid	NOUN
dpc-2310	127	26	,	,	PUNCT
dpc-2310	127	27	hepatitis	hepatitis	PROPN
dpc-2310	127	28	b	b	PROPN
dpc-2310	127	29	and	and	CCONJ
dpc-2310	127	30	c	c	PROPN
dpc-2310	127	31	markers	marker	NOUN
dpc-2310	127	32	,	,	PUNCT
dpc-2310	127	33	hiv	hiv	PROPN
dpc-2310	127	34	and	and	CCONJ
dpc-2310	127	35	hcg	hcg	PROPN
dpc-2310	127	36	if	if	SCONJ
dpc-2310	127	37	indicated	indicate	VERB
dpc-2310	127	38	.	.	PUNCT
dpc-2310	128	1	during	during	ADP
dpc-2310	128	2	the	the	DET
dpc-2310	128	3	therapy	therapy	NOUN
dpc-2310	128	4	,	,	PUNCT
dpc-2310	128	5	blood	blood	NOUN
dpc-2310	128	6	tests	test	NOUN
dpc-2310	128	7	should	should	AUX
dpc-2310	128	8	be	be	AUX
dpc-2310	128	9	tested	test	VERB
dpc-2310	128	10	monthly	monthly	ADV
dpc-2310	128	11	.	.	PUNCT
dpc-2310	129	1	there	there	PRON
dpc-2310	129	2	are	be	VERB
dpc-2310	129	3	no	no	DET
dpc-2310	129	4	data	datum	NOUN
dpc-2310	129	5	about	about	ADP
dpc-2310	129	6	use	use	NOUN
dpc-2310	129	7	of	of	ADP
dpc-2310	129	8	mtx	mtx	NOUN
dpc-2310	129	9	in	in	ADP
dpc-2310	129	10	children	child	NOUN
dpc-2310	129	11	affected	affect	VERB
dpc-2310	129	12	by	by	ADP
dpc-2310	129	13	ad	ad	NOUN
dpc-2310	129	14	.	.	PUNCT
dpc-2310	130	1	multiple	multiple	ADJ
dpc-2310	130	2	studies	study	NOUN
dpc-2310	130	3	regarding	regard	VERB
dpc-2310	130	4	its	its	PRON
dpc-2310	130	5	use	use	NOUN
dpc-2310	130	6	in	in	ADP
dpc-2310	130	7	pediatric	pediatric	ADJ
dpc-2310	130	8	patients	patient	NOUN
dpc-2310	130	9	with	with	ADP
dpc-2310	130	10	psoriasis	psoriasis	NOUN
dpc-2310	130	11	show	show	NOUN
dpc-2310	130	12	mtx	mtx	NOUN
dpc-2310	130	13	as	as	ADP
dpc-2310	130	14	a	a	DET
dpc-2310	130	15	safe	safe	ADJ
dpc-2310	130	16	,	,	PUNCT
dpc-2310	130	17	effective	effective	ADJ
dpc-2310	130	18	,	,	PUNCT
dpc-2310	130	19	and	and	CCONJ
dpc-2310	130	20	well	well	ADV
dpc-2310	130	21	-	-	PUNCT
dpc-2310	130	22	tolerated	tolerate	VERB
dpc-2310	130	23	medication	medication	NOUN
dpc-2310	130	24	[	[	X
dpc-2310	130	25	10	10	NUM
dpc-2310	130	26	]	]	PUNCT
dpc-2310	130	27	.	.	PUNCT
dpc-2310	131	1	like	like	INTJ
dpc-2310	131	2	ccsa	ccsa	PROPN
dpc-2310	131	3	,	,	PUNCT
dpc-2310	131	4	mtx	mtx	NOUN
dpc-2310	131	5	can	can	AUX
dpc-2310	131	6	be	be	AUX
dpc-2310	131	7	associated	associate	VERB
dpc-2310	131	8	with	with	ADP
dpc-2310	131	9	dupilumab	dupilumab	NOUN
dpc-2310	131	10	in	in	ADP
dpc-2310	131	11	recalcitrant	recalcitrant	ADJ
dpc-2310	131	12	patients	patient	NOUN
dpc-2310	131	13	,	,	PUNCT
dpc-2310	131	14	maintaining	maintain	VERB
dpc-2310	131	15	a	a	DET
dpc-2310	131	16	good	good	ADJ
dpc-2310	131	17	safety	safety	NOUN
dpc-2310	131	18	profile	profile	NOUN
dpc-2310	132	1	[	[	X
dpc-2310	132	2	17	17	NUM
dpc-2310	132	3	]	]	PUNCT
dpc-2310	132	4	.	.	PUNCT
dpc-2310	133	1	azathioprine	azathioprine	PROPN
dpc-2310	133	2	azathioprine	azathioprine	PROPN
dpc-2310	133	3	(	(	PUNCT
dpc-2310	133	4	aza	aza	PROPN
dpc-2310	133	5	)	)	PUNCT
dpc-2310	133	6	is	be	AUX
dpc-2310	133	7	a	a	DET
dpc-2310	133	8	purine	purine	NOUN
dpc-2310	133	9	analog	analog	NOUN
dpc-2310	133	10	that	that	PRON
dpc-2310	133	11	inhibits	inhibit	VERB
dpc-2310	133	12	dna	dna	PROPN
dpc-2310	133	13	production	production	NOUN
dpc-2310	133	14	,	,	PUNCT
dpc-2310	133	15	thus	thus	ADV
dpc-2310	133	16	preferentially	preferentially	ADV
dpc-2310	133	17	affecting	affect	VERB
dpc-2310	133	18	cells	cell	NOUN
dpc-2310	133	19	with	with	ADP
dpc-2310	133	20	high	high	ADJ
dpc-2310	133	21	proliferation	proliferation	NOUN
dpc-2310	133	22	rates	rate	NOUN
dpc-2310	133	23	,	,	PUNCT
dpc-2310	133	24	such	such	ADJ
dpc-2310	133	25	as	as	ADP
dpc-2310	133	26	b	b	NOUN
dpc-2310	133	27	-	-	PUNCT
dpc-2310	133	28	cells	cell	NOUN
dpc-2310	133	29	and	and	CCONJ
dpc-2310	133	30	t	t	NOUN
dpc-2310	133	31	-	-	PUNCT
dpc-2310	133	32	cells	cell	NOUN
dpc-2310	133	33	during	during	ADP
dpc-2310	133	34	inflammatory	inflammatory	ADJ
dpc-2310	133	35	disease	disease	NOUN
dpc-2310	133	36	states	state	NOUN
dpc-2310	133	37	.	.	PUNCT
dpc-2310	134	1	it	it	PRON
dpc-2310	134	2	is	be	AUX
dpc-2310	134	3	used	use	VERB
dpc-2310	134	4	off	off	ADP
dpc-2310	134	5	-	-	PUNCT
dpc-2310	134	6	label	label	NOUN
dpc-2310	134	7	to	to	PART
dpc-2310	134	8	treat	treat	VERB
dpc-2310	134	9	inflammatory	inflammatory	ADJ
dpc-2310	134	10	cutaneous	cutaneous	ADJ
dpc-2310	134	11	and	and	CCONJ
dpc-2310	134	12	systemic	systemic	ADJ
dpc-2310	134	13	disorders	disorder	NOUN
dpc-2310	134	14	,	,	PUNCT
dpc-2310	134	15	including	include	VERB
dpc-2310	134	16	refractory	refractory	NOUN
dpc-2310	134	17	ad	ad	NOUN
dpc-2310	134	18	with	with	ADP
dpc-2310	134	19	moderate	moderate	ADJ
dpc-2310	134	20	improvement	improvement	NOUN
dpc-2310	134	21	of	of	ADP
dpc-2310	134	22	dermatitis	dermatitis	NOUN
dpc-2310	134	23	(	(	PUNCT
dpc-2310	134	24	equal	equal	ADJ
dpc-2310	134	25	to	to	ADP
dpc-2310	134	26	a	a	DET
dpc-2310	134	27	37	37	NUM
dpc-2310	134	28	%	%	NOUN
dpc-2310	134	29	reduction	reduction	NOUN
dpc-2310	134	30	of	of	ADP
dpc-2310	134	31	disease	disease	NOUN
dpc-2310	134	32	,	,	PUNCT
dpc-2310	134	33	measured	measure	VERB
dpc-2310	134	34	by	by	ADP
dpc-2310	134	35	the	the	DET
dpc-2310	134	36	six	six	NUM
dpc-2310	134	37	area	area	NOUN
dpc-2310	134	38	,	,	PUNCT
dpc-2310	134	39	six	six	NUM
dpc-2310	134	40	sign	sign	NOUN
dpc-2310	134	41	ad	ad	NOUN
dpc-2310	134	42	scoring	scoring	NOUN
dpc-2310	134	43	system	system	NOUN
dpc-2310	134	44	after	after	ADP
dpc-2310	134	45	12	12	NUM
dpc-2310	134	46	weeks	week	NOUN
dpc-2310	134	47	)	)	PUNCT
dpc-2310	135	1	[	[	X
dpc-2310	135	2	18	18	NUM
dpc-2310	135	3	]	]	PUNCT
dpc-2310	135	4	.	.	PUNCT
dpc-2310	136	1	a	a	DET
dpc-2310	136	2	delayed	delay	VERB
dpc-2310	136	3	effect	effect	NOUN
dpc-2310	136	4	may	may	AUX
dpc-2310	136	5	be	be	AUX
dpc-2310	136	6	noted	note	VERB
dpc-2310	136	7	,	,	PUNCT
dpc-2310	136	8	with	with	ADP
dpc-2310	136	9	some	some	DET
dpc-2310	136	10	patients	patient	NOUN
dpc-2310	136	11	needing	need	VERB
dpc-2310	136	12	a	a	DET
dpc-2310	136	13	treatment	treatment	NOUN
dpc-2310	136	14	for	for	ADP
dpc-2310	136	15	12	12	NUM
dpc-2310	136	16	weeks	week	NOUN
dpc-2310	136	17	or	or	CCONJ
dpc-2310	136	18	longer	long	ADV
dpc-2310	136	19	to	to	PART
dpc-2310	136	20	achieve	achieve	VERB
dpc-2310	136	21	full	full	ADJ
dpc-2310	136	22	clinical	clinical	ADJ
dpc-2310	136	23	benefit	benefit	NOUN
dpc-2310	136	24	.	.	PUNCT
dpc-2310	137	1	the	the	DET
dpc-2310	137	2	dose	dose	NOUN
dpc-2310	137	3	range	range	NOUN
dpc-2310	137	4	is	be	AUX
dpc-2310	137	5	variable	variable	ADJ
dpc-2310	137	6	between	between	ADP
dpc-2310	137	7	1	1	NUM
dpc-2310	137	8	to	to	PART
dpc-2310	137	9	3	3	NUM
dpc-2310	137	10	mg	mg	PROPN
dpc-2310	137	11	/	/	SYM
dpc-2310	137	12	kg	kg	PROPN
dpc-2310	137	13	/	/	PROPN
dpc-2310	137	14	d.	d.	PROPN
dpc-2310	137	15	aza	aza	PROPN
dpc-2310	137	16	is	be	AUX
dpc-2310	137	17	available	available	ADJ
dpc-2310	137	18	in	in	ADP
dpc-2310	137	19	tablet	tablet	ADJ
dpc-2310	137	20	form	form	NOUN
dpc-2310	137	21	only	only	ADV
dpc-2310	137	22	and	and	CCONJ
dpc-2310	137	23	may	may	AUX
dpc-2310	137	24	be	be	AUX
dpc-2310	137	25	given	give	VERB
dpc-2310	137	26	once	once	ADV
dpc-2310	137	27	daily	daily	ADV
dpc-2310	137	28	.	.	PUNCT
dpc-2310	138	1	graduated	graduate	VERB
dpc-2310	138	2	dosing	dose	VERB
dpc-2310	138	3	to	to	PART
dpc-2310	138	4	maximize	maximize	VERB
dpc-2310	138	5	benefit	benefit	NOUN
dpc-2310	138	6	while	while	SCONJ
dpc-2310	138	7	limiting	limit	VERB
dpc-2310	138	8	side	side	NOUN
dpc-2310	138	9	effects	effect	NOUN
dpc-2310	138	10	is	be	AUX
dpc-2310	138	11	preferred	prefer	VERB
dpc-2310	138	12	,	,	PUNCT
dpc-2310	138	13	as	as	SCONJ
dpc-2310	138	14	a	a	DET
dpc-2310	138	15	considerable	considerable	ADJ
dpc-2310	138	16	number	number	NOUN
dpc-2310	138	17	of	of	ADP
dpc-2310	138	18	patients	patient	NOUN
dpc-2310	138	19	develops	develop	VERB
dpc-2310	138	20	intolerable	intolerable	ADJ
dpc-2310	138	21	nausea	nausea	NOUN
dpc-2310	138	22	and	and	CCONJ
dpc-2310	138	23	vomiting	vomit	VERB
dpc-2310	138	24	at	at	ADP
dpc-2310	138	25	higher	high	ADJ
dpc-2310	138	26	doses	dose	NOUN
dpc-2310	138	27	.	.	PUNCT
dpc-2310	139	1	the	the	DET
dpc-2310	139	2	metabolism	metabolism	NOUN
dpc-2310	139	3	of	of	ADP
dpc-2310	139	4	aza	aza	NOUN
dpc-2310	139	5	is	be	AUX
dpc-2310	139	6	dependent	dependent	ADJ
dpc-2310	139	7	on	on	ADP
dpc-2310	139	8	an	an	DET
dpc-2310	139	9	review	review	NOUN
dpc-2310	139	10	|	|	ADV
dpc-2310	139	11	dermatol	dermatol	ADJ
dpc-2310	139	12	pract	pract	NOUN
dpc-2310	139	13	concept	concept	NOUN
dpc-2310	139	14	.	.	PUNCT
dpc-2310	140	1	2022;12(1):e2022155	2022;12(1):e2022155	NUM
dpc-2310	140	2	5	5	NUM
dpc-2310	140	3	table	table	NOUN
dpc-2310	140	4	1	1	NUM
dpc-2310	140	5	.	.	PUNCT
dpc-2310	140	6	key	key	ADJ
dpc-2310	140	7	points	point	NOUN
dpc-2310	140	8	moisturizers	moisturizer	NOUN
dpc-2310	140	9	integral	integral	ADJ
dpc-2310	140	10	part	part	NOUN
dpc-2310	140	11	of	of	ADP
dpc-2310	140	12	ad	ad	NOUN
dpc-2310	140	13	therapy	therapy	NOUN
dpc-2310	140	14	,	,	PUNCT
dpc-2310	140	15	including	include	VERB
dpc-2310	140	16	in	in	ADP
dpc-2310	140	17	patients	patient	NOUN
dpc-2310	140	18	on	on	ADP
dpc-2310	140	19	biological	biological	ADJ
dpc-2310	140	20	treatment	treatment	NOUN
dpc-2310	140	21	since	since	SCONJ
dpc-2310	140	22	it	it	PRON
dpc-2310	140	23	is	be	AUX
dpc-2310	140	24	able	able	ADJ
dpc-2310	140	25	to	to	PART
dpc-2310	140	26	reduce	reduce	VERB
dpc-2310	140	27	inflammation	inflammation	NOUN
dpc-2310	140	28	and	and	CCONJ
dpc-2310	140	29	itching	itching	NOUN
dpc-2310	140	30	but	but	CCONJ
dpc-2310	140	31	not	not	PART
dpc-2310	140	32	xerosis	xerosis	NOUN
dpc-2310	140	33	.	.	PUNCT
dpc-2310	141	1	topical	topical	ADJ
dpc-2310	141	2	corticosteroids	corticosteroid	NOUN
dpc-2310	141	3	recommended	recommend	VERB
dpc-2310	141	4	for	for	ADP
dpc-2310	141	5	mild	mild	ADJ
dpc-2310	141	6	-	-	PUNCT
dpc-2310	141	7	to	to	ADP
dpc-2310	141	8	-	-	PUNCT
dpc-2310	141	9	moderate	moderate	ADJ
dpc-2310	141	10	forms	form	NOUN
dpc-2310	141	11	;	;	PUNCT
dpc-2310	141	12	they	they	PRON
dpc-2310	141	13	can	can	AUX
dpc-2310	141	14	be	be	AUX
dpc-2310	141	15	also	also	ADV
dpc-2310	141	16	helpful	helpful	ADJ
dpc-2310	141	17	to	to	PART
dpc-2310	141	18	accelerate	accelerate	VERB
dpc-2310	141	19	the	the	DET
dpc-2310	141	20	response	response	NOUN
dpc-2310	141	21	to	to	ADP
dpc-2310	141	22	systemic	systemic	ADJ
dpc-2310	141	23	drugs	drug	NOUN
dpc-2310	141	24	,	,	PUNCT
dpc-2310	141	25	including	include	VERB
dpc-2310	141	26	biologics	biologic	NOUN
dpc-2310	141	27	,	,	PUNCT
dpc-2310	141	28	to	to	PART
dpc-2310	141	29	increase	increase	VERB
dpc-2310	141	30	the	the	DET
dpc-2310	141	31	efficacy	efficacy	NOUN
dpc-2310	141	32	and	and	CCONJ
dpc-2310	141	33	to	to	PART
dpc-2310	141	34	control	control	VERB
dpc-2310	141	35	the	the	DET
dpc-2310	141	36	flares	flare	NOUN
dpc-2310	141	37	.	.	PUNCT
dpc-2310	142	1	topical	topical	ADJ
dpc-2310	142	2	calcineurin	calcineurin	NOUN
dpc-2310	142	3	inhibitors	inhibitor	NOUN
dpc-2310	142	4	recommended	recommend	VERB
dpc-2310	142	5	as	as	ADP
dpc-2310	142	6	steroid	steroid	NOUN
dpc-2310	142	7	-	-	PUNCT
dpc-2310	142	8	sparing	spare	VERB
dpc-2310	142	9	agents	agent	NOUN
dpc-2310	142	10	in	in	ADP
dpc-2310	142	11	long	long	ADJ
dpc-2310	142	12	term	term	NOUN
dpc-2310	142	13	therapy	therapy	NOUN
dpc-2310	142	14	and	and	CCONJ
dpc-2310	142	15	mostly	mostly	ADV
dpc-2310	142	16	for	for	ADP
dpc-2310	142	17	the	the	DET
dpc-2310	142	18	sensitive	sensitive	ADJ
dpc-2310	142	19	areas	area	NOUN
dpc-2310	142	20	(	(	PUNCT
dpc-2310	142	21	face	face	NOUN
dpc-2310	142	22	,	,	PUNCT
dpc-2310	142	23	skin	skin	NOUN
dpc-2310	142	24	folds	fold	NOUN
dpc-2310	142	25	and	and	CCONJ
dpc-2310	142	26	genitals	genital	NOUN
dpc-2310	142	27	)	)	PUNCT
dpc-2310	142	28	.	.	PUNCT
dpc-2310	143	1	useful	useful	ADJ
dpc-2310	143	2	to	to	PART
dpc-2310	143	3	treat	treat	VERB
dpc-2310	143	4	facial	facial	ADJ
dpc-2310	143	5	dermatitis	dermatitis	NOUN
dpc-2310	143	6	(	(	PUNCT
dpc-2310	143	7	not	not	PART
dpc-2310	143	8	responsive	responsive	ADJ
dpc-2310	143	9	to	to	ADP
dpc-2310	143	10	dupilumab	dupilumab	NOUN
dpc-2310	143	11	or	or	CCONJ
dpc-2310	143	12	dupilumab	dupilumab	NOUN
dpc-2310	143	13	associated	associate	VERB
dpc-2310	143	14	)	)	PUNCT
dpc-2310	143	15	and	and	CCONJ
dpc-2310	143	16	to	to	PART
dpc-2310	143	17	prevent	prevent	VERB
dpc-2310	143	18	dupilumab	dupilumab	NOUN
dpc-2310	143	19	associated	associate	VERB
dpc-2310	143	20	conjunctivitis	conjunctivitis	NOUN
dpc-2310	143	21	,	,	PUNCT
dpc-2310	143	22	if	if	SCONJ
dpc-2310	143	23	peripalpebral	peripalpebral	ADJ
dpc-2310	143	24	eczema	eczema	NOUN
dpc-2310	143	25	is	be	AUX
dpc-2310	143	26	present	present	ADJ
dpc-2310	143	27	.	.	PUNCT
dpc-2310	144	1	phototherapy	phototherapy	NOUN
dpc-2310	144	2	used	use	VERB
dpc-2310	144	3	as	as	ADP
dpc-2310	144	4	second	second	ADJ
dpc-2310	144	5	-	-	PUNCT
dpc-2310	144	6	line	line	NOUN
dpc-2310	144	7	treatment	treatment	NOUN
dpc-2310	144	8	,	,	PUNCT
dpc-2310	144	9	after	after	ADP
dpc-2310	144	10	failure	failure	NOUN
dpc-2310	144	11	of	of	ADP
dpc-2310	144	12	first	first	ADJ
dpc-2310	144	13	-	-	PUNCT
dpc-2310	144	14	line	line	NOUN
dpc-2310	144	15	treatment	treatment	NOUN
dpc-2310	144	16	(	(	PUNCT
dpc-2310	144	17	emollients	emollient	NOUN
dpc-2310	144	18	,	,	PUNCT
dpc-2310	144	19	topical	topical	ADJ
dpc-2310	144	20	steroids	steroid	NOUN
dpc-2310	144	21	,	,	PUNCT
dpc-2310	144	22	and	and	CCONJ
dpc-2310	144	23	topical	topical	ADJ
dpc-2310	144	24	calcineurin	calcineurin	NOUN
dpc-2310	144	25	inhibitors	inhibitor	NOUN
dpc-2310	144	26	)	)	PUNCT
dpc-2310	144	27	,	,	PUNCT
dpc-2310	144	28	or	or	CCONJ
dpc-2310	144	29	as	as	ADP
dpc-2310	144	30	maintenance	maintenance	NOUN
dpc-2310	144	31	therapy	therapy	NOUN
dpc-2310	144	32	in	in	ADP
dpc-2310	144	33	patients	patient	NOUN
dpc-2310	144	34	with	with	ADP
dpc-2310	144	35	chronic	chronic	ADJ
dpc-2310	144	36	disease	disease	NOUN
dpc-2310	144	37	.	.	PUNCT
dpc-2310	145	1	traditional	traditional	ADJ
dpc-2310	145	2	systemic	systemic	ADJ
dpc-2310	145	3	drugs	drug	NOUN
dpc-2310	145	4	first	first	ADJ
dpc-2310	145	5	line	line	NOUN
dpc-2310	145	6	therapy	therapy	NOUN
dpc-2310	145	7	for	for	ADP
dpc-2310	145	8	severe	severe	ADJ
dpc-2310	145	9	forms	form	NOUN
dpc-2310	145	10	and	and	CCONJ
dpc-2310	145	11	a	a	DET
dpc-2310	145	12	valid	valid	ADJ
dpc-2310	145	13	choice	choice	NOUN
dpc-2310	145	14	in	in	ADP
dpc-2310	145	15	combination	combination	NOUN
dpc-2310	145	16	with	with	ADP
dpc-2310	145	17	dupilumab	dupilumab	NOUN
dpc-2310	145	18	and	and	CCONJ
dpc-2310	145	19	in	in	ADP
dpc-2310	145	20	case	case	NOUN
dpc-2310	145	21	of	of	ADP
dpc-2310	145	22	inadequate	inadequate	ADJ
dpc-2310	145	23	response	response	NOUN
dpc-2310	145	24	to	to	ADP
dpc-2310	145	25	biological	biological	ADJ
dpc-2310	145	26	drug	drug	NOUN
dpc-2310	145	27	,	,	PUNCT
dpc-2310	145	28	maintaining	maintain	VERB
dpc-2310	145	29	a	a	DET
dpc-2310	145	30	good	good	ADJ
dpc-2310	145	31	safety	safety	NOUN
dpc-2310	145	32	profile	profile	NOUN
dpc-2310	145	33	.	.	PUNCT
dpc-2310	146	1	references	reference	NOUN
dpc-2310	146	2	1	1	NUM
dpc-2310	146	3	.	.	PUNCT
dpc-2310	146	4	blauvelt	blauvelt	VERB
dpc-2310	146	5	a	a	DET
dpc-2310	146	6	,	,	PUNCT
dpc-2310	146	7	de	de	X
dpc-2310	146	8	bruin	bruin	NOUN
dpc-2310	146	9	-	-	PUNCT
dpc-2310	146	10	weller	weller	PROPN
dpc-2310	146	11	m	m	PROPN
dpc-2310	146	12	,	,	PUNCT
dpc-2310	146	13	gooderham	gooderham	PROPN
dpc-2310	146	14	m	m	PROPN
dpc-2310	146	15	,	,	PUNCT
dpc-2310	146	16	et	et	PROPN
dpc-2310	146	17	al	al	PROPN
dpc-2310	146	18	.	.	PROPN
dpc-2310	147	1	longterm	longterm	PROPN
dpc-2310	147	2	management	management	NOUN
dpc-2310	147	3	of	of	ADP
dpc-2310	147	4	moderate	moderate	ADJ
dpc-2310	147	5	-	-	PUNCT
dpc-2310	147	6	to	to	ADP
dpc-2310	147	7	-	-	PUNCT
dpc-2310	147	8	severe	severe	ADJ
dpc-2310	147	9	atopic	atopic	NOUN
dpc-2310	147	10	dermatitis	dermatitis	NOUN
dpc-2310	147	11	with	with	ADP
dpc-2310	147	12	dupilumab	dupilumab	NOUN
dpc-2310	147	13	and	and	CCONJ
dpc-2310	147	14	concomitant	concomitant	ADJ
dpc-2310	147	15	topical	topical	ADJ
dpc-2310	147	16	corticosteroids	corticosteroid	NOUN
dpc-2310	147	17	(	(	PUNCT
dpc-2310	147	18	liberty	liberty	NOUN
dpc-2310	147	19	ad	ad	NOUN
dpc-2310	147	20	chronos	chrono	NOUN
dpc-2310	147	21	):	):	PUNCT
dpc-2310	147	22	a	a	DET
dpc-2310	147	23	1	1	NUM
dpc-2310	147	24	-	-	PUNCT
dpc-2310	147	25	year	year	NOUN
dpc-2310	147	26	,	,	PUNCT
dpc-2310	147	27	randomised	randomise	VERB
dpc-2310	147	28	,	,	PUNCT
dpc-2310	147	29	double	double	ADJ
dpc-2310	147	30	-	-	PUNCT
dpc-2310	147	31	blinded	blind	VERB
dpc-2310	147	32	,	,	PUNCT
dpc-2310	147	33	placebo	placebo	NOUN
dpc-2310	147	34	-	-	PUNCT
dpc-2310	147	35	controlled	control	VERB
dpc-2310	147	36	,	,	PUNCT
dpc-2310	147	37	phase	phase	NOUN
dpc-2310	147	38	3	3	NUM
dpc-2310	147	39	trial	trial	NOUN
dpc-2310	147	40	.	.	PUNCT
dpc-2310	147	41	 	 	SPACE
dpc-2310	148	1	lancet	lancet	PROPN
dpc-2310	148	2	.	.	PUNCT
dpc-2310	149	1	2017;389	2017;389	NUM
dpc-2310	149	2	(	(	PUNCT
dpc-2310	149	3	10086	10086	NUM
dpc-2310	149	4	):	):	PUNCT
dpc-2310	149	5	2287‐2303	2287‐2303	NUM
dpc-2310	149	6	.	.	PUNCT
dpc-2310	150	1	doi	doi	NOUN
dpc-2310	150	2	:	:	PUNCT
dpc-2310	150	3	10.1016	10.1016	NUM
dpc-2310	150	4	/	/	SYM
dpc-2310	150	5	s0140	s0140	PROPN
dpc-2310	150	6	-	-	PUNCT
dpc-2310	150	7	6736(17)31191	6736(17)31191	NOUN
dpc-2310	150	8	-	-	PUNCT
dpc-2310	150	9	1	1	NUM
dpc-2310	150	10	.	.	PUNCT
dpc-2310	151	1	pmid	pmid	NOUN
dpc-2310	151	2	:	:	PUNCT
dpc-2310	151	3	28478972	28478972	NUM
dpc-2310	151	4	.	.	PUNCT
dpc-2310	152	1	2	2	X
dpc-2310	152	2	.	.	X
dpc-2310	152	3	silverberg	silverberg	PROPN
dpc-2310	152	4	ji	ji	PROPN
dpc-2310	152	5	,	,	PUNCT
dpc-2310	152	6	yosipovitch	yosipovitch	VERB
dpc-2310	152	7	g	g	PROPN
dpc-2310	152	8	,	,	PUNCT
dpc-2310	152	9	simpson	simpson	PROPN
dpc-2310	152	10	el	el	PROPN
dpc-2310	152	11	,	,	PUNCT
dpc-2310	152	12	et	et	PROPN
dpc-2310	152	13	al	al	PROPN
dpc-2310	152	14	.	.	PROPN
dpc-2310	152	15	dupilumab	dupilumab	NOUN
dpc-2310	152	16	treatment	treatment	NOUN
dpc-2310	152	17	results	result	NOUN
dpc-2310	152	18	in	in	ADP
dpc-2310	152	19	early	early	ADJ
dpc-2310	152	20	and	and	CCONJ
dpc-2310	152	21	sustained	sustained	ADJ
dpc-2310	152	22	improvements	improvement	NOUN
dpc-2310	152	23	in	in	ADP
dpc-2310	152	24	itch	itch	NOUN
dpc-2310	152	25	in	in	ADP
dpc-2310	152	26	adolescents	adolescent	NOUN
dpc-2310	152	27	and	and	CCONJ
dpc-2310	152	28	adults	adult	NOUN
dpc-2310	152	29	with	with	ADP
dpc-2310	152	30	moderate	moderate	ADJ
dpc-2310	152	31	to	to	ADP
dpc-2310	152	32	severe	severe	ADJ
dpc-2310	152	33	atopic	atopic	NOUN
dpc-2310	152	34	dermatitis	dermatitis	NOUN
dpc-2310	152	35	:	:	PUNCT
dpc-2310	152	36	analysis	analysis	NOUN
dpc-2310	152	37	of	of	ADP
dpc-2310	152	38	the	the	DET
dpc-2310	152	39	randomized	randomized	ADJ
dpc-2310	152	40	phase	phase	NOUN
dpc-2310	152	41	3	3	NUM
dpc-2310	152	42	studies	study	NOUN
dpc-2310	152	43	solo	solo	ADV
dpc-2310	152	44	1	1	NUM
dpc-2310	152	45	and	and	CCONJ
dpc-2310	152	46	solo	solo	ADJ
dpc-2310	152	47	2	2	NUM
dpc-2310	152	48	,	,	PUNCT
dpc-2310	152	49	ad	ad	NOUN
dpc-2310	152	50	adol	adol	NOUN
dpc-2310	152	51	,	,	PUNCT
dpc-2310	152	52	and	and	CCONJ
dpc-2310	152	53	chronos	chrono	NOUN
dpc-2310	152	54	.	.	PUNCT
dpc-2310	153	1	j	j	PROPN
dpc-2310	153	2	am	be	AUX
dpc-2310	153	3	acad	acad	ADJ
dpc-2310	153	4	dermatol	dermatol	NOUN
dpc-2310	153	5	.	.	PUNCT
dpc-2310	154	1	2020;82(6):1328	2020;82(6):1328	NUM
dpc-2310	154	2	-	-	SYM
dpc-2310	154	3	1336	1336	NUM
dpc-2310	154	4	.	.	PUNCT
dpc-2310	155	1	doi	doi	NOUN
dpc-2310	155	2	:	:	PUNCT
dpc-2310	155	3	10.1016	10.1016	NUM
dpc-2310	155	4	/	/	SYM
dpc-2310	155	5	j.jaad.2020.02.060	j.jaad.2020.02.060	PROPN
dpc-2310	155	6	.	.	PUNCT
dpc-2310	156	1	pmid	pmid	NOUN
dpc-2310	156	2	:	:	PUNCT
dpc-2310	156	3	32135208	32135208	NUM
dpc-2310	156	4	.	.	PUNCT
dpc-2310	157	1	3	3	X
dpc-2310	157	2	.	.	NOUN
dpc-2310	157	3	chiricozzi	chiricozzi	PROPN
dpc-2310	157	4	a	a	NOUN
dpc-2310	157	5	,	,	PUNCT
dpc-2310	157	6	maurelli	maurelli	NOUN
dpc-2310	157	7	m	m	PROPN
dpc-2310	157	8	,	,	PUNCT
dpc-2310	157	9	gori	gori	PROPN
dpc-2310	157	10	n	n	CCONJ
dpc-2310	157	11	,	,	PUNCT
dpc-2310	157	12	et	et	PROPN
dpc-2310	157	13	al	al	PROPN
dpc-2310	157	14	.	.	PROPN
dpc-2310	157	15	dupilumab	dupilumab	NOUN
dpc-2310	157	16	improves	improve	VERB
dpc-2310	157	17	clinical	clinical	ADJ
dpc-2310	157	18	manifestations	manifestation	NOUN
dpc-2310	157	19	,	,	PUNCT
dpc-2310	157	20	symptoms	symptom	NOUN
dpc-2310	157	21	,	,	PUNCT
dpc-2310	157	22	and	and	CCONJ
dpc-2310	157	23	quality	quality	NOUN
dpc-2310	157	24	of	of	ADP
dpc-2310	157	25	life	life	NOUN
dpc-2310	157	26	in	in	ADP
dpc-2310	157	27	adult	adult	NOUN
dpc-2310	157	28	patients	patient	NOUN
dpc-2310	157	29	with	with	ADP
dpc-2310	157	30	chronic	chronic	ADJ
dpc-2310	157	31	nodular	nodular	ADJ
dpc-2310	157	32	prurigo	prurigo	NOUN
dpc-2310	157	33	.	.	PUNCT
dpc-2310	158	1	j	j	PROPN
dpc-2310	158	2	am	be	AUX
dpc-2310	158	3	acad	acad	ADJ
dpc-2310	158	4	dermatol	dermatol	NOUN
dpc-2310	158	5	.	.	PUNCT
dpc-2310	159	1	2020;83(1):39–45	2020;83(1):39–45	X
dpc-2310	159	2	.	.	PUNCT
dpc-2310	159	3	doi	doi	NOUN
dpc-2310	159	4	:	:	PUNCT
dpc-2310	159	5	10.1016	10.1016	NUM
dpc-2310	159	6	/	/	SYM
dpc-2310	159	7	j.jaad.2020.03.049	j.jaad.2020.03.049	PROPN
dpc-2310	159	8	.	.	PUNCT
dpc-2310	160	1	pmid	pmid	NOUN
dpc-2310	160	2	:	:	PUNCT
dpc-2310	160	3	32229281	32229281	NUM
dpc-2310	160	4	.	.	PUNCT
dpc-2310	161	1	4	4	X
dpc-2310	161	2	.	.	X
dpc-2310	161	3	ribero	ribero	PROPN
dpc-2310	161	4	s	s	PROPN
dpc-2310	161	5	,	,	PUNCT
dpc-2310	161	6	giura	giura	PROPN
dpc-2310	161	7	mt	mt	PROPN
dpc-2310	161	8	,	,	PUNCT
dpc-2310	161	9	viola	viola	PROPN
dpc-2310	161	10	r	r	PROPN
dpc-2310	161	11	,	,	PUNCT
dpc-2310	161	12	et	et	PROPN
dpc-2310	161	13	al	al	PROPN
dpc-2310	161	14	.	.	PROPN
dpc-2310	161	15	effectiveness	effectiveness	NOUN
dpc-2310	161	16	and	and	CCONJ
dpc-2310	161	17	safety	safety	NOUN
dpc-2310	161	18	of	of	ADP
dpc-2310	161	19	dupilumab	dupilumab	NOUN
dpc-2310	161	20	for	for	ADP
dpc-2310	161	21	the	the	DET
dpc-2310	161	22	treatment	treatment	NOUN
dpc-2310	161	23	of	of	ADP
dpc-2310	161	24	atopic	atopic	NOUN
dpc-2310	161	25	dermatitis	dermatitis	NOUN
dpc-2310	161	26	in	in	ADP
dpc-2310	161	27	adult	adult	NOUN
dpc-2310	161	28	cohort	cohort	NOUN
dpc-2310	161	29	:	:	PUNCT
dpc-2310	161	30	a	a	DET
dpc-2310	161	31	real	real	ADJ
dpc-2310	161	32	-	-	PUNCT
dpc-2310	161	33	life	life	NOUN
dpc-2310	161	34	italian	italian	ADJ
dpc-2310	161	35	tertiary	tertiary	ADJ
dpc-2310	161	36	centre	centre	NOUN
dpc-2310	161	37	experience	experience	NOUN
dpc-2310	161	38	.	.	PUNCT
dpc-2310	162	1	j	j	PROPN
dpc-2310	162	2	eur	eur	PROPN
dpc-2310	162	3	acad	acad	PROPN
dpc-2310	162	4	dermatol	dermatol	NOUN
dpc-2310	162	5	venereol	venereol	NOUN
dpc-2310	162	6	.	.	PUNCT
dpc-2310	163	1	2020;34(8):e380	2020;34(8):e380	NOUN
dpc-2310	163	2	-	-	PUNCT
dpc-2310	163	3	e383	e383	PROPN
dpc-2310	163	4	.	.	PUNCT
dpc-2310	163	5	doi	doi	NOUN
dpc-2310	163	6	:	:	PUNCT
dpc-2310	163	7	10.1111	10.1111	NUM
dpc-2310	163	8	/	/	SYM
dpc-2310	163	9	jdv.16219	jdv.16219	PROPN
dpc-2310	163	10	.	.	PUNCT
dpc-2310	164	1	pmid	pmid	NOUN
dpc-2310	164	2	:	:	PUNCT
dpc-2310	164	3	31960496	31960496	NUM
dpc-2310	164	4	.	.	PUNCT
dpc-2310	165	1	5	5	X
dpc-2310	165	2	.	.	X
dpc-2310	165	3	eichenfield	eichenfield	PROPN
dpc-2310	165	4	lf	lf	PROPN
dpc-2310	165	5	,	,	PUNCT
dpc-2310	165	6	tom	tom	PROPN
dpc-2310	165	7	wl	wl	PROPN
dpc-2310	165	8	,	,	PUNCT
dpc-2310	165	9	berger	berger	PROPN
dpc-2310	165	10	tg	tg	PROPN
dpc-2310	165	11	,	,	PUNCT
dpc-2310	165	12	et	et	PROPN
dpc-2310	165	13	al	al	PROPN
dpc-2310	165	14	.	.	PUNCT
dpc-2310	165	15	guidelines	guideline	NOUN
dpc-2310	165	16	of	of	ADP
dpc-2310	165	17	care	care	NOUN
dpc-2310	165	18	for	for	ADP
dpc-2310	165	19	the	the	DET
dpc-2310	165	20	management	management	NOUN
dpc-2310	165	21	of	of	ADP
dpc-2310	165	22	atopic	atopic	NOUN
dpc-2310	165	23	dermatitis	dermatitis	NOUN
dpc-2310	165	24	:	:	PUNCT
dpc-2310	165	25	section	section	NOUN
dpc-2310	165	26	2	2	NUM
dpc-2310	165	27	.	.	PUNCT
dpc-2310	165	28	management	management	NOUN
dpc-2310	165	29	and	and	CCONJ
dpc-2310	165	30	treatment	treatment	NOUN
dpc-2310	165	31	of	of	ADP
dpc-2310	165	32	atopic	atopic	NOUN
dpc-2310	165	33	dermatitis	dermatitis	NOUN
dpc-2310	165	34	with	with	ADP
dpc-2310	165	35	topical	topical	ADJ
dpc-2310	165	36	therapies	therapy	NOUN
dpc-2310	165	37	.	.	PUNCT
dpc-2310	166	1	j	j	PROPN
dpc-2310	166	2	am	be	AUX
dpc-2310	166	3	acad	acad	ADJ
dpc-2310	166	4	dermatol	dermatol	NOUN
dpc-2310	166	5	.	.	PUNCT
dpc-2310	167	1	2014;71(1):116	2014;71(1):116	NUM
dpc-2310	167	2	-	-	PUNCT
dpc-2310	167	3	32	32	NUM
dpc-2310	167	4	.	.	PUNCT
dpc-2310	168	1	doi	doi	NOUN
dpc-2310	168	2	:	:	PUNCT
dpc-2310	168	3	10.1016	10.1016	NUM
dpc-2310	168	4	/	/	SYM
dpc-2310	168	5	j.	j.	PROPN
dpc-2310	168	6	jaad.2014.03.023	jaad.2014.03.023	PROPN
dpc-2310	168	7	.	.	PUNCT
dpc-2310	169	1	pmid	pmid	PROPN
dpc-2310	169	2	:	:	PUNCT
dpc-2310	169	3	24813302	24813302	NUM
dpc-2310	169	4	.	.	PUNCT
dpc-2310	170	1	pmcid	pmcid	ADJ
dpc-2310	170	2	:	:	PUNCT
dpc-2310	170	3	pmc4326095	pmc4326095	NOUN
dpc-2310	170	4	.	.	PUNCT
dpc-2310	171	1	6	6	X
dpc-2310	171	2	.	.	PUNCT
dpc-2310	171	3	rawlings	rawlings	PROPN
dpc-2310	171	4	av	av	PROPN
dpc-2310	171	5	,	,	PUNCT
dpc-2310	171	6	canestrari	canestrari	PROPN
dpc-2310	171	7	da	da	PROPN
dpc-2310	171	8	,	,	PUNCT
dpc-2310	171	9	dobkowski	dobkowski	PROPN
dpc-2310	171	10	b.	b.	PROPN
dpc-2310	171	11	moisturizer	moisturizer	PROPN
dpc-2310	171	12	technology	technology	NOUN
dpc-2310	171	13	versus	versus	ADP
dpc-2310	171	14	clinical	clinical	ADJ
dpc-2310	171	15	performance	performance	NOUN
dpc-2310	171	16	.	.	PUNCT
dpc-2310	172	1	dermatol	dermatol	NOUN
dpc-2310	172	2	ther	ther	ADV
dpc-2310	172	3	.	.	PUNCT
dpc-2310	173	1	2004;17	2004;17	NUM
dpc-2310	173	2	suppl	suppl	ADJ
dpc-2310	173	3	1:49	1:49	NUM
dpc-2310	173	4	-	-	SYM
dpc-2310	173	5	56	56	NUM
dpc-2310	173	6	.	.	PUNCT
dpc-2310	174	1	doi	doi	NOUN
dpc-2310	174	2	:	:	PUNCT
dpc-2310	174	3	10.1111	10.1111	NUM
dpc-2310	174	4	/	/	SYM
dpc-2310	174	5	j.1396	j.1396	ADP
dpc-2310	174	6	-	-	PUNCT
dpc-2310	174	7	0296.2004.04s1006.x	0296.2004.04s1006.x	NOUN
dpc-2310	174	8	.	.	PUNCT
dpc-2310	175	1	pmid	pmid	NOUN
dpc-2310	175	2	:	:	PUNCT
dpc-2310	175	3	14728699	14728699	NUM
dpc-2310	175	4	.	.	PUNCT
dpc-2310	176	1	7	7	X
dpc-2310	176	2	.	.	X
dpc-2310	176	3	draelos	draelos	PROPN
dpc-2310	176	4	zd	zd	PROPN
dpc-2310	176	5	.	.	PUNCT
dpc-2310	177	1	an	an	DET
dpc-2310	177	2	evaluation	evaluation	NOUN
dpc-2310	177	3	of	of	ADP
dpc-2310	177	4	prescription	prescription	NOUN
dpc-2310	177	5	device	device	NOUN
dpc-2310	177	6	moisturizers	moisturizer	NOUN
dpc-2310	177	7	.	.	PUNCT
dpc-2310	178	1	j	j	PROPN
dpc-2310	178	2	cosmet	cosmet	PROPN
dpc-2310	178	3	dermatol	dermatol	NOUN
dpc-2310	178	4	.	.	PUNCT
dpc-2310	179	1	2009;8(1):40	2009;8(1):40	NUM
dpc-2310	179	2	-	-	SYM
dpc-2310	179	3	43	43	NUM
dpc-2310	179	4	.	.	PUNCT
dpc-2310	180	1	doi	doi	NOUN
dpc-2310	180	2	:	:	PUNCT
dpc-2310	181	1	10.1111	10.1111	NUM
dpc-2310	181	2	/	/	SYM
dpc-2310	181	3	j.14732165.2009.00422.x	j.14732165.2009.00422.x	PROPN
dpc-2310	181	4	.	.	PUNCT
dpc-2310	181	5	pmid	pmid	PROPN
dpc-2310	181	6	:	:	PUNCT
dpc-2310	181	7	19250165	19250165	NUM
dpc-2310	181	8	.	.	PUNCT
dpc-2310	182	1	8	8	X
dpc-2310	182	2	.	.	X
dpc-2310	182	3	dabade	dabade	NOUN
dpc-2310	182	4	ts	ts	PROPN
dpc-2310	182	5	,	,	PUNCT
dpc-2310	182	6	davis	davis	PROPN
dpc-2310	182	7	dm	dm	PROPN
dpc-2310	182	8	,	,	PUNCT
dpc-2310	182	9	wetter	wetter	NOUN
dpc-2310	182	10	da	da	NOUN
dpc-2310	182	11	,	,	PUNCT
dpc-2310	182	12	et	et	PROPN
dpc-2310	182	13	al	al	PROPN
dpc-2310	182	14	.	.	PUNCT
dpc-2310	183	1	wet	wet	ADJ
dpc-2310	183	2	dressing	dressing	NOUN
dpc-2310	183	3	therapy	therapy	NOUN
dpc-2310	183	4	in	in	ADP
dpc-2310	183	5	conjunction	conjunction	NOUN
dpc-2310	183	6	with	with	ADP
dpc-2310	183	7	topical	topical	ADJ
dpc-2310	183	8	corticosteroids	corticosteroid	NOUN
dpc-2310	183	9	is	be	AUX
dpc-2310	183	10	effective	effective	ADJ
dpc-2310	183	11	for	for	ADP
dpc-2310	183	12	rapid	rapid	ADJ
dpc-2310	183	13	control	control	NOUN
dpc-2310	183	14	of	of	ADP
dpc-2310	183	15	severe	severe	ADJ
dpc-2310	183	16	pediatric	pediatric	ADJ
dpc-2310	183	17	atopic	atopic	NOUN
dpc-2310	183	18	dermatitis	dermatitis	NOUN
dpc-2310	183	19	:	:	PUNCT
dpc-2310	183	20	experience	experience	NOUN
dpc-2310	183	21	with	with	ADP
dpc-2310	183	22	218	218	NUM
dpc-2310	183	23	patients	patient	NOUN
dpc-2310	183	24	over	over	ADP
dpc-2310	183	25	30	30	NUM
dpc-2310	183	26	years	year	NOUN
dpc-2310	183	27	at	at	ADP
dpc-2310	183	28	mayo	mayo	PROPN
dpc-2310	183	29	clinic	clinic	PROPN
dpc-2310	183	30	.	.	PUNCT
dpc-2310	184	1	j	j	PROPN
dpc-2310	184	2	am	be	AUX
dpc-2310	184	3	acad	acad	ADJ
dpc-2310	184	4	dermatol	dermatol	NOUN
dpc-2310	184	5	.	.	PUNCT
dpc-2310	185	1	2012;67(1):100	2012;67(1):100	NUM
dpc-2310	185	2	-	-	SYM
dpc-2310	185	3	6	6	NUM
dpc-2310	185	4	.	.	PUNCT
dpc-2310	186	1	doi	doi	NOUN
dpc-2310	186	2	:	:	PUNCT
dpc-2310	186	3	10.1016	10.1016	NUM
dpc-2310	186	4	/	/	SYM
dpc-2310	186	5	j.jaad.2011.06.025	j.jaad.2011.06.025	PROPN
dpc-2310	186	6	.	.	PUNCT
dpc-2310	187	1	pmid	pmid	NOUN
dpc-2310	187	2	:	:	PUNCT
dpc-2310	187	3	21978575	21978575	NUM
dpc-2310	187	4	.	.	PUNCT
dpc-2310	188	1	9	9	X
dpc-2310	188	2	.	.	X
dpc-2310	188	3	devillers	deviller	NOUN
dpc-2310	188	4	ac	ac	PROPN
dpc-2310	188	5	,	,	PUNCT
dpc-2310	188	6	oranje	oranje	PROPN
dpc-2310	188	7	ap	ap	PROPN
dpc-2310	188	8	.	.	PUNCT
dpc-2310	189	1	efficacy	efficacy	NOUN
dpc-2310	189	2	and	and	CCONJ
dpc-2310	189	3	safety	safety	NOUN
dpc-2310	189	4	of	of	ADP
dpc-2310	189	5	‘	'	PUNCT
dpc-2310	189	6	wet	wet	ADJ
dpc-2310	189	7	-	-	PUNCT
dpc-2310	189	8	wrap	wrap	NOUN
dpc-2310	189	9	’	'	PUNCT
dpc-2310	189	10	dressings	dressing	NOUN
dpc-2310	189	11	as	as	ADP
dpc-2310	189	12	an	an	DET
dpc-2310	189	13	intervention	intervention	NOUN
dpc-2310	189	14	treatment	treatment	NOUN
dpc-2310	189	15	in	in	ADP
dpc-2310	189	16	children	child	NOUN
dpc-2310	189	17	with	with	ADP
dpc-2310	189	18	severe	severe	ADJ
dpc-2310	189	19	and/or	and/or	CCONJ
dpc-2310	189	20	refractory	refractory	NOUN
dpc-2310	189	21	atopic	atopic	NOUN
dpc-2310	189	22	dermatitis	dermatitis	NOUN
dpc-2310	189	23	:	:	PUNCT
dpc-2310	189	24	a	a	DET
dpc-2310	189	25	critical	critical	ADJ
dpc-2310	189	26	review	review	NOUN
dpc-2310	189	27	of	of	ADP
dpc-2310	189	28	the	the	DET
dpc-2310	189	29	literature	literature	NOUN
dpc-2310	189	30	.	.	PUNCT
dpc-2310	190	1	br	br	PROPN
dpc-2310	190	2	j	j	PROPN
dpc-2310	190	3	dermatol	dermatol	NOUN
dpc-2310	190	4	.	.	PUNCT
dpc-2310	191	1	2006;154(4):579	2006;154(4):579	NUM
dpc-2310	191	2	-	-	SYM
dpc-2310	191	3	585	585	NUM
dpc-2310	191	4	.	.	PUNCT
dpc-2310	191	5	doi	doi	NOUN
dpc-2310	191	6	:	:	PUNCT
dpc-2310	191	7	10.1111	10.1111	NUM
dpc-2310	191	8	/	/	SYM
dpc-2310	191	9	j.13652133.2006.07157.x	j.13652133.2006.07157.x	NOUN
dpc-2310	191	10	.	.	PUNCT
dpc-2310	192	1	pmid	pmid	NOUN
dpc-2310	192	2	:	:	PUNCT
dpc-2310	192	3	16536797	16536797	NUM
dpc-2310	192	4	.	.	PUNCT
dpc-2310	193	1	10	10	NUM
dpc-2310	193	2	.	.	PUNCT
dpc-2310	194	1	sidbury	sidbury	PROPN
dpc-2310	194	2	r	r	PROPN
dpc-2310	194	3	,	,	PUNCT
dpc-2310	194	4	davis	davis	PROPN
dpc-2310	194	5	dm	dm	PROPN
dpc-2310	194	6	,	,	PUNCT
dpc-2310	194	7	cohen	cohen	PROPN
dpc-2310	194	8	de	de	PROPN
dpc-2310	194	9	,	,	PUNCT
dpc-2310	194	10	et	et	PROPN
dpc-2310	194	11	al	al	PROPN
dpc-2310	194	12	.	.	PUNCT
dpc-2310	194	13	guidelines	guideline	NOUN
dpc-2310	194	14	of	of	ADP
dpc-2310	194	15	care	care	NOUN
dpc-2310	194	16	for	for	ADP
dpc-2310	194	17	the	the	DET
dpc-2310	194	18	management	management	NOUN
dpc-2310	194	19	of	of	ADP
dpc-2310	194	20	atopic	atopic	NOUN
dpc-2310	194	21	dermatitis	dermatitis	NOUN
dpc-2310	194	22	:	:	PUNCT
dpc-2310	194	23	section	section	NOUN
dpc-2310	194	24	3	3	NUM
dpc-2310	194	25	.	.	PUNCT
dpc-2310	194	26	management	management	NOUN
dpc-2310	194	27	and	and	CCONJ
dpc-2310	194	28	treatment	treatment	NOUN
dpc-2310	194	29	with	with	ADP
dpc-2310	194	30	phototherapy	phototherapy	NOUN
dpc-2310	194	31	and	and	CCONJ
dpc-2310	194	32	systemic	systemic	ADJ
dpc-2310	194	33	agents	agent	NOUN
dpc-2310	194	34	.	.	PUNCT
dpc-2310	195	1	j	j	PROPN
dpc-2310	195	2	am	be	AUX
dpc-2310	195	3	acad	acad	ADJ
dpc-2310	195	4	dermatol	dermatol	NOUN
dpc-2310	195	5	.	.	PUNCT
dpc-2310	196	1	2014;71(2):327	2014;71(2):327	NUM
dpc-2310	196	2	-	-	SYM
dpc-2310	196	3	349	349	NUM
dpc-2310	196	4	.	.	PUNCT
dpc-2310	197	1	doi	doi	NOUN
dpc-2310	197	2	:	:	PUNCT
dpc-2310	197	3	10.1016	10.1016	NUM
dpc-2310	197	4	/	/	SYM
dpc-2310	197	5	j.jaad.2014.03.030	j.jaad.2014.03.030	PROPN
dpc-2310	197	6	.	.	PUNCT
dpc-2310	198	1	pmid	pmid	NOUN
dpc-2310	198	2	:	:	PUNCT
dpc-2310	198	3	24813298	24813298	NUM
dpc-2310	198	4	.	.	PUNCT
dpc-2310	199	1	pmcid	pmcid	NOUN
dpc-2310	199	2	:	:	PUNCT
dpc-2310	199	3	pmc4410179	pmc4410179	NOUN
dpc-2310	199	4	.	.	PUNCT
dpc-2310	200	1	11	11	NUM
dpc-2310	200	2	.	.	PUNCT
dpc-2310	200	3	nolan	nolan	PROPN
dpc-2310	200	4	k	k	PROPN
dpc-2310	200	5	,	,	PUNCT
dpc-2310	200	6	marmur	marmur	ADJ
dpc-2310	200	7	e.	e.	PROPN
dpc-2310	200	8	moisturizers	moisturizer	NOUN
dpc-2310	200	9	:	:	PUNCT
dpc-2310	200	10	reality	reality	NOUN
dpc-2310	200	11	and	and	CCONJ
dpc-2310	200	12	the	the	DET
dpc-2310	200	13	skin	skin	NOUN
dpc-2310	200	14	benefits	benefit	NOUN
dpc-2310	200	15	.	.	PUNCT
dpc-2310	201	1	dermatol	dermatol	NOUN
dpc-2310	201	2	ther	ther	ADV
dpc-2310	201	3	.	.	PUNCT
dpc-2310	202	1	2012;25(3):229	2012;25(3):229	NUM
dpc-2310	202	2	-	-	PUNCT
dpc-2310	202	3	233	233	NUM
dpc-2310	202	4	.	.	PUNCT
dpc-2310	203	1	doi	doi	NOUN
dpc-2310	203	2	:	:	PUNCT
dpc-2310	203	3	10.1111	10.1111	NUM
dpc-2310	203	4	/	/	SYM
dpc-2310	203	5	j.15298019.2012.01504.x	j.15298019.2012.01504.x	PROPN
dpc-2310	203	6	.	.	PUNCT
dpc-2310	204	1	pmid	pmid	NOUN
dpc-2310	204	2	:	:	PUNCT
dpc-2310	204	3	22913439	22913439	NUM
dpc-2310	204	4	.	.	PUNCT
dpc-2310	205	1	12	12	NUM
dpc-2310	205	2	.	.	PUNCT
dpc-2310	206	1	furuhashi	furuhashi	PROPN
dpc-2310	206	2	t	t	PROPN
dpc-2310	206	3	,	,	PUNCT
dpc-2310	206	4	oda	oda	PROPN
dpc-2310	206	5	t	t	PROPN
dpc-2310	206	6	,	,	PUNCT
dpc-2310	206	7	torii	torii	PROPN
dpc-2310	206	8	k	k	PROPN
dpc-2310	206	9	,	,	PUNCT
dpc-2310	206	10	nishida	nishida	PROPN
dpc-2310	206	11	e	e	PROPN
dpc-2310	206	12	,	,	PUNCT
dpc-2310	206	13	morita	morita	PROPN
dpc-2310	206	14	a.	a.	PROPN
dpc-2310	206	15	dupilumab	dupilumab	NOUN
dpc-2310	206	16	probably	probably	ADV
dpc-2310	206	17	reduces	reduce	VERB
dpc-2310	206	18	transepidermal	transepidermal	ADJ
dpc-2310	206	19	water	water	NOUN
dpc-2310	206	20	loss	loss	NOUN
dpc-2310	206	21	but	but	CCONJ
dpc-2310	206	22	does	do	AUX
dpc-2310	206	23	not	not	PART
dpc-2310	206	24	increase	increase	VERB
dpc-2310	206	25	stratum	stratum	NOUN
dpc-2310	206	26	corneum	corneum	NOUN
dpc-2310	206	27	hydration	hydration	NOUN
dpc-2310	206	28	in	in	ADP
dpc-2310	206	29	atopic	atopic	NOUN
dpc-2310	206	30	dermatitis	dermatitis	NOUN
dpc-2310	206	31	.	.	PUNCT
dpc-2310	207	1	j	j	PROPN
dpc-2310	207	2	dermatol	dermatol	NOUN
dpc-2310	207	3	.	.	PUNCT
dpc-2310	208	1	2021;48(2):e74	2021;48(2):e74	NUM
dpc-2310	208	2	-	-	PUNCT
dpc-2310	208	3	e75	e75	NUM
dpc-2310	208	4	.	.	PUNCT
dpc-2310	209	1	doi	doi	NOUN
dpc-2310	209	2	:	:	PUNCT
dpc-2310	209	3	10.1111/1346	10.1111/1346	NUM
dpc-2310	209	4	-	-	SYM
dpc-2310	209	5	8138.15638	8138.15638	NUM
dpc-2310	209	6	.	.	PUNCT
dpc-2310	210	1	pmid	pmid	NOUN
dpc-2310	210	2	:	:	PUNCT
dpc-2310	210	3	33035368	33035368	NUM
dpc-2310	210	4	;	;	PUNCT
dpc-2310	210	5	pmcid	pmcid	NOUN
dpc-2310	210	6	:	:	PUNCT
dpc-2310	210	7	pmc7891664	pmc7891664	NOUN
dpc-2310	210	8	.	.	PUNCT
dpc-2310	211	1	13	13	NUM
dpc-2310	211	2	.	.	PUNCT
dpc-2310	211	3	blauvelt	blauvelt	VERB
dpc-2310	211	4	a	a	DET
dpc-2310	211	5	,	,	PUNCT
dpc-2310	211	6	de	de	X
dpc-2310	211	7	bruin	bruin	NOUN
dpc-2310	211	8	-	-	PUNCT
dpc-2310	211	9	weller	weller	PROPN
dpc-2310	211	10	m	m	PROPN
dpc-2310	211	11	,	,	PUNCT
dpc-2310	211	12	gooderham	gooderham	PROPN
dpc-2310	211	13	m	m	PROPN
dpc-2310	211	14	,	,	PUNCT
dpc-2310	211	15	et	et	PROPN
dpc-2310	211	16	al	al	PROPN
dpc-2310	211	17	.	.	PUNCT
dpc-2310	212	1	long	long	ADJ
dpc-2310	212	2	-	-	PUNCT
dpc-2310	212	3	term	term	NOUN
dpc-2310	212	4	management	management	NOUN
dpc-2310	212	5	of	of	ADP
dpc-2310	212	6	moderate	moderate	ADJ
dpc-2310	212	7	-	-	PUNCT
dpc-2310	212	8	to	to	ADP
dpc-2310	212	9	-	-	PUNCT
dpc-2310	212	10	severe	severe	ADJ
dpc-2310	212	11	atopic	atopic	NOUN
dpc-2310	212	12	dermatitis	dermatitis	NOUN
dpc-2310	212	13	with	with	ADP
dpc-2310	212	14	dupilumab	dupilumab	NOUN
dpc-2310	212	15	and	and	CCONJ
dpc-2310	212	16	concomitant	concomitant	ADJ
dpc-2310	212	17	topical	topical	ADJ
dpc-2310	212	18	corticosteroids	corticosteroid	NOUN
dpc-2310	212	19	(	(	PUNCT
dpc-2310	212	20	liberty	liberty	NOUN
dpc-2310	212	21	ad	ad	NOUN
dpc-2310	212	22	chronos	chrono	NOUN
dpc-2310	212	23	):	):	PUNCT
dpc-2310	212	24	a	a	DET
dpc-2310	212	25	1	1	NUM
dpc-2310	212	26	-	-	PUNCT
dpc-2310	212	27	year	year	NOUN
dpc-2310	212	28	,	,	PUNCT
dpc-2310	212	29	randomised	randomise	VERB
dpc-2310	212	30	,	,	PUNCT
dpc-2310	212	31	double	double	ADJ
dpc-2310	212	32	-	-	PUNCT
dpc-2310	212	33	blinded	blind	VERB
dpc-2310	212	34	,	,	PUNCT
dpc-2310	212	35	placebo	placebo	NOUN
dpc-2310	212	36	controlled	control	VERB
dpc-2310	212	37	,	,	PUNCT
dpc-2310	212	38	phase	phase	NOUN
dpc-2310	212	39	3	3	NUM
dpc-2310	212	40	trial	trial	NOUN
dpc-2310	212	41	.	.	PUNCT
dpc-2310	212	42	 	 	SPACE
dpc-2310	213	1	lancet	lancet	NOUN
dpc-2310	213	2	.	.	PUNCT
dpc-2310	214	1	2017;389(10086):2287‐2303	2017;389(10086):2287‐2303	NUM
dpc-2310	214	2	.	.	PUNCT
dpc-2310	215	1	doi	doi	NOUN
dpc-2310	215	2	:	:	PUNCT
dpc-2310	215	3	10.1016	10.1016	NUM
dpc-2310	215	4	/	/	SYM
dpc-2310	215	5	s0140	s0140	PROPN
dpc-2310	215	6	-	-	PUNCT
dpc-2310	215	7	6736(17)31191	6736(17)31191	NOUN
dpc-2310	215	8	-	-	PUNCT
dpc-2310	215	9	1	1	NUM
dpc-2310	215	10	.	.	PUNCT
dpc-2310	216	1	pmid	pmid	NOUN
dpc-2310	216	2	:	:	PUNCT
dpc-2310	216	3	28478972	28478972	NUM
dpc-2310	216	4	.	.	PUNCT
dpc-2310	217	1	14	14	NUM
dpc-2310	217	2	.	.	PUNCT
dpc-2310	217	3	treister	treister	NOUN
dpc-2310	217	4	ad	ad	NOUN
dpc-2310	217	5	,	,	PUNCT
dpc-2310	217	6	kraff	kraff	PROPN
dpc-2310	217	7	-	-	PUNCT
dpc-2310	217	8	cooper	cooper	PROPN
dpc-2310	217	9	c	c	PROPN
dpc-2310	217	10	,	,	PUNCT
dpc-2310	217	11	lio	lio	PROPN
dpc-2310	217	12	pa	pa	PROPN
dpc-2310	217	13	.	.	PROPN
dpc-2310	217	14	risk	risk	NOUN
dpc-2310	217	15	factors	factor	NOUN
dpc-2310	217	16	for	for	ADP
dpc-2310	217	17	dupilumab	dupilumab	NOUN
dpc-2310	217	18	associated	associate	VERB
dpc-2310	217	19	conjunctivitis	conjunctivitis	NOUN
dpc-2310	217	20	in	in	ADP
dpc-2310	217	21	patients	patient	NOUN
dpc-2310	217	22	with	with	ADP
dpc-2310	217	23	atopic	atopic	NOUN
dpc-2310	217	24	dermatitis	dermatitis	NOUN
dpc-2310	217	25	.	.	PUNCT
dpc-2310	217	26	 	 	SPACE
dpc-2310	217	27	jama	jama	PROPN
dpc-2310	217	28	dermatol	dermatol	NOUN
dpc-2310	217	29	.	.	PUNCT
dpc-2310	218	1	2018;154(10):1208‐1211	2018;154(10):1208‐1211	X
dpc-2310	218	2	.	.	PUNCT
dpc-2310	218	3	doi	doi	NOUN
dpc-2310	218	4	:	:	PUNCT
dpc-2310	218	5	10.1001	10.1001	NUM
dpc-2310	218	6	/	/	SYM
dpc-2310	218	7	jamadermatol.2018.2690	jamadermatol.2018.2690	PROPN
dpc-2310	218	8	.	.	PUNCT
dpc-2310	219	1	pmid	pmid	NOUN
dpc-2310	219	2	:	:	PUNCT
dpc-2310	219	3	30167653	30167653	NUM
dpc-2310	219	4	.	.	PUNCT
dpc-2310	220	1	pmcid	pmcid	NOUN
dpc-2310	220	2	:	:	PUNCT
dpc-2310	220	3	pmc6233741	pmc6233741	ADJ
dpc-2310	220	4	.	.	PUNCT
dpc-2310	221	1	15	15	X
dpc-2310	221	2	.	.	X
dpc-2310	221	3	calabrese	calabrese	PROPN
dpc-2310	221	4	g	g	PROPN
dpc-2310	221	5	,	,	PUNCT
dpc-2310	221	6	gambardella	gambardella	VERB
dpc-2310	221	7	a	a	PRON
dpc-2310	221	8	,	,	PUNCT
dpc-2310	221	9	licata	licata	NOUN
dpc-2310	221	10	g	g	PROPN
dpc-2310	221	11	,	,	PUNCT
dpc-2310	221	12	di	di	PROPN
dpc-2310	221	13	brizzi	brizzi	PROPN
dpc-2310	221	14	ev	ev	PROPN
dpc-2310	221	15	,	,	PUNCT
dpc-2310	221	16	alfano	alfano	PROPN
dpc-2310	221	17	r	r	NOUN
dpc-2310	221	18	,	,	PUNCT
dpc-2310	221	19	argenziano	argenziano	ADJ
dpc-2310	221	20	g.	g.	NOUN
dpc-2310	221	21	dupilumab	dupilumab	NOUN
dpc-2310	221	22	and	and	CCONJ
dpc-2310	221	23	conjunctivitis	conjunctivitis	NOUN
dpc-2310	221	24	:	:	PUNCT
dpc-2310	221	25	a	a	DET
dpc-2310	221	26	case	case	NOUN
dpc-2310	221	27	series	series	NOUN
dpc-2310	221	28	of	of	ADP
dpc-2310	221	29	twenty	twenty	NUM
dpc-2310	221	30	patients	patient	NOUN
dpc-2310	221	31	.	.	PUNCT
dpc-2310	222	1	j	j	PROPN
dpc-2310	222	2	eur	eur	PROPN
dpc-2310	222	3	acad	acad	PROPN
dpc-2310	222	4	dermatol	dermatol	NOUN
dpc-2310	222	5	venereol	venereol	NOUN
dpc-2310	222	6	.	.	PUNCT
dpc-2310	223	1	2021;35(9):e612	2021;35(9):e612	NOUN
dpc-2310	223	2	-	-	PUNCT
dpc-2310	223	3	e614	e614	PROPN
dpc-2310	223	4	.	.	PUNCT
dpc-2310	223	5	doi	doi	NOUN
dpc-2310	223	6	:	:	PUNCT
dpc-2310	223	7	10.1111	10.1111	NUM
dpc-2310	223	8	/	/	SYM
dpc-2310	223	9	jdv.17210	jdv.17210	PROPN
dpc-2310	223	10	.	.	PUNCT
dpc-2310	224	1	pmid	pmid	NOUN
dpc-2310	224	2	:	:	PUNCT
dpc-2310	224	3	33657247	33657247	NUM
dpc-2310	224	4	.	.	PUNCT
dpc-2310	225	1	16	16	NUM
dpc-2310	225	2	.	.	PUNCT
dpc-2310	226	1	jaros	jaros	PROPN
dpc-2310	226	2	j	j	PROPN
dpc-2310	226	3	,	,	PUNCT
dpc-2310	226	4	hendricks	hendricks	PROPN
dpc-2310	226	5	aj	aj	PROPN
dpc-2310	226	6	,	,	PUNCT
dpc-2310	226	7	shi	shi	PROPN
dpc-2310	226	8	vy	vy	PROPN
dpc-2310	226	9	,	,	PUNCT
dpc-2310	226	10	lio	lio	PROPN
dpc-2310	226	11	pa	pa	PROPN
dpc-2310	226	12	.	.	PROPN
dpc-2310	227	1	a	a	DET
dpc-2310	227	2	practical	practical	ADJ
dpc-2310	227	3	approach	approach	NOUN
dpc-2310	227	4	to	to	ADP
dpc-2310	227	5	recalcitrant	recalcitrant	ADJ
dpc-2310	227	6	face	face	NOUN
dpc-2310	227	7	and	and	CCONJ
dpc-2310	227	8	neck	neck	NOUN
dpc-2310	227	9	dermatitis	dermatitis	NOUN
dpc-2310	227	10	in	in	ADP
dpc-2310	227	11	atopic	atopic	NOUN
dpc-2310	227	12	dermatitis	dermatitis	NOUN
dpc-2310	227	13	.	.	PUNCT
dpc-2310	228	1	dermatitis	dermatitis	NOUN
dpc-2310	228	2	.	.	PUNCT
dpc-2310	229	1	2020;31(3):169	2020;31(3):169	NUM
dpc-2310	229	2	-	-	PUNCT
dpc-2310	229	3	177	177	NUM
dpc-2310	229	4	.	.	PUNCT
dpc-2310	230	1	doi	doi	NOUN
dpc-2310	230	2	:	:	PUNCT
dpc-2310	230	3	10.1097	10.1097	NUM
dpc-2310	230	4	/	/	SYM
dpc-2310	230	5	der.0000000000000590	der.0000000000000590	NUM
dpc-2310	230	6	.	.	PUNCT
dpc-2310	231	1	pmid	pmid	NOUN
dpc-2310	231	2	:	:	PUNCT
dpc-2310	231	3	32355092	32355092	NUM
dpc-2310	231	4	.	.	PUNCT
dpc-2310	232	1	17	17	NUM
dpc-2310	232	2	.	.	X
dpc-2310	232	3	gori	gori	PROPN
dpc-2310	232	4	n	n	SYM
dpc-2310	232	5	,	,	PUNCT
dpc-2310	232	6	 	 	SPACE
dpc-2310	232	7	chiricozzi	chiricozzi	NOUN
dpc-2310	232	8	 	 	SPACE
dpc-2310	232	9	a	a	DET
dpc-2310	232	10	,	,	PUNCT
dpc-2310	232	11	 	 	SPACE
dpc-2310	232	12	malvaso	malvaso	NOUN
dpc-2310	232	13	 	 	SPACE
dpc-2310	232	14	d	d	PROPN
dpc-2310	232	15	,	,	PUNCT
dpc-2310	232	16	 	 	SPACE
dpc-2310	232	17	et	et	PROPN
dpc-2310	232	18	al	al	PROPN
dpc-2310	232	19	.	.	PROPN
dpc-2310	232	20	successful	successful	ADJ
dpc-2310	232	21	combination	combination	NOUN
dpc-2310	232	22	of	of	ADP
dpc-2310	232	23	systemic	systemic	ADJ
dpc-2310	232	24	agents	agent	NOUN
dpc-2310	232	25	for	for	ADP
dpc-2310	232	26	the	the	DET
dpc-2310	232	27	treatment	treatment	NOUN
dpc-2310	232	28	of	of	ADP
dpc-2310	232	29	atopic	atopic	NOUN
dpc-2310	232	30	dermatitis	dermatitis	NOUN
dpc-2310	232	31	resistant	resistant	ADJ
dpc-2310	232	32	to	to	ADP
dpc-2310	232	33	dupilumab	dupilumab	NOUN
dpc-2310	232	34	therapy	therapy	NOUN
dpc-2310	232	35	.	.	PUNCT
dpc-2310	233	1	dermatology	dermatology	NOUN
dpc-2310	233	2	.	.	PUNCT
dpc-2310	234	1	2021;237(4):535541	2021;237(4):535541	NUM
dpc-2310	234	2	.	.	PUNCT
dpc-2310	235	1	doi	doi	NOUN
dpc-2310	235	2	:	:	PUNCT
dpc-2310	235	3	10.1159/000512890	10.1159/000512890	NUM
dpc-2310	235	4	.	.	PUNCT
dpc-2310	236	1	pmid	pmid	NOUN
dpc-2310	236	2	:	:	PUNCT
dpc-2310	236	3	33477153	33477153	NUM
dpc-2310	236	4	.	.	PUNCT
dpc-2310	237	1	18	18	NUM
dpc-2310	237	2	.	.	PUNCT
dpc-2310	238	1	meggitt	meggitt	AUX
dpc-2310	238	2	sj	sj	PROPN
dpc-2310	238	3	,	,	PUNCT
dpc-2310	238	4	gray	gray	PROPN
dpc-2310	238	5	jc	jc	PROPN
dpc-2310	238	6	,	,	PUNCT
dpc-2310	238	7	reynolds	reynolds	PROPN
dpc-2310	238	8	nj	nj	PROPN
dpc-2310	238	9	.	.	PROPN
dpc-2310	238	10	azathioprine	azathioprine	PROPN
dpc-2310	238	11	dosed	dose	VERB
dpc-2310	238	12	by	by	ADP
dpc-2310	238	13	thiopurine	thiopurine	NOUN
dpc-2310	238	14	methyltransferase	methyltransferase	NOUN
dpc-2310	238	15	activity	activity	NOUN
dpc-2310	238	16	for	for	ADP
dpc-2310	238	17	moderate	moderate	ADJ
dpc-2310	238	18	-	-	PUNCT
dpc-2310	238	19	to	to	ADP
dpc-2310	238	20	-	-	PUNCT
dpc-2310	238	21	severe	severe	ADJ
dpc-2310	238	22	atopic	atopic	NOUN
dpc-2310	238	23	eczema	eczema	NOUN
dpc-2310	238	24	:	:	PUNCT
dpc-2310	238	25	a	a	DET
dpc-2310	238	26	double	double	ADJ
dpc-2310	238	27	-	-	PUNCT
dpc-2310	238	28	blind	blind	ADJ
dpc-2310	238	29	,	,	PUNCT
dpc-2310	238	30	randomised	randomise	VERB
dpc-2310	238	31	controlled	control	VERB
dpc-2310	238	32	trial	trial	NOUN
dpc-2310	238	33	.	.	PUNCT
dpc-2310	239	1	lancet	lancet	NOUN
dpc-2310	239	2	.	.	PUNCT
dpc-2310	240	1	2006	2006	NUM
dpc-2310	240	2	;	;	PUNCT
dpc-2310	240	3	367:839	367:839	NUM
dpc-2310	240	4	–	–	PUNCT
dpc-2310	240	5	846	846	NUM
dpc-2310	240	6	.	.	PUNCT
dpc-2310	241	1	doi	doi	NOUN
dpc-2310	241	2	:	:	PUNCT
dpc-2310	241	3	10.1016	10.1016	NUM
dpc-2310	241	4	/	/	SYM
dpc-2310	241	5	s0140	s0140	PROPN
dpc-2310	241	6	-	-	PUNCT
dpc-2310	241	7	6736(06)68340	6736(06)68340	NUM
dpc-2310	241	8	-	-	PUNCT
dpc-2310	241	9	2	2	NUM
dpc-2310	241	10	.	.	PUNCT
dpc-2310	241	11	pmid	pmid	NOUN
dpc-2310	241	12	:	:	PUNCT
dpc-2310	241	13	16530578	16530578	NUM
dpc-2310	241	14	.	.	PUNCT