id	sid	tid	token	lemma	pos
dpc-2345	1	1	dermatology	dermatology	NOUN
dpc-2345	1	2	:	:	PUNCT
dpc-2345	1	3	practical	practical	ADJ
dpc-2345	1	4	and	and	CCONJ
dpc-2345	1	5	conceptual	conceptual	ADJ
dpc-2345	1	6	review	review	NOUN
dpc-2345	1	7	|	|	ADV
dpc-2345	1	8	dermatol	dermatol	ADJ
dpc-2345	1	9	pract	pract	NOUN
dpc-2345	1	10	concept	concept	NOUN
dpc-2345	1	11	.	.	PUNCT
dpc-2345	2	1	2022;12(4):e2022202	2022;12(4):e2022202	NUM
dpc-2345	2	2	1	1	NUM
dpc-2345	2	3	investigation	investigation	NOUN
dpc-2345	2	4	on	on	ADP
dpc-2345	2	5	utility	utility	NOUN
dpc-2345	2	6	of	of	ADP
dpc-2345	2	7	some	some	DET
dpc-2345	2	8	novel	novel	ADJ
dpc-2345	2	9	terpenes	terpene	NOUN
dpc-2345	2	10	on	on	ADP
dpc-2345	2	11	transungual	transungual	ADJ
dpc-2345	2	12	delivery	delivery	NOUN
dpc-2345	2	13	of	of	ADP
dpc-2345	2	14	terbinafine	terbinafine	NOUN
dpc-2345	2	15	for	for	ADP
dpc-2345	2	16	the	the	DET
dpc-2345	2	17	management	management	NOUN
dpc-2345	2	18	of	of	ADP
dpc-2345	2	19	onychomycosis	onychomycosis	NOUN
dpc-2345	2	20	isha	isha	ADJ
dpc-2345	2	21	gupta1	gupta1	NOUN
dpc-2345	2	22	,	,	PUNCT
dpc-2345	2	23	syeda	syeda	PROPN
dpc-2345	2	24	nashvia	nashvia	PROPN
dpc-2345	2	25	adin1	adin1	PROPN
dpc-2345	2	26	,	,	PUNCT
dpc-2345	2	27	mohd	mohd	PROPN
dpc-2345	2	28	.	.	PUNCT
dpc-2345	3	1	aqil2	aqil2	PROPN
dpc-2345	3	2	,	,	PUNCT
dpc-2345	3	3	mohd	mohd	PROPN
dpc-2345	3	4	.	.	PUNCT
dpc-2345	4	1	mujeeb1	mujeeb1	PROPN
dpc-2345	4	2	,	,	PUNCT
dpc-2345	4	3	yasmin	yasmin	PROPN
dpc-2345	4	4	sultana2	sultana2	PROPN
dpc-2345	4	5	1	1	NUM
dpc-2345	4	6	department	department	NOUN
dpc-2345	4	7	of	of	ADP
dpc-2345	4	8	pharmacognosy	pharmacognosy	NOUN
dpc-2345	4	9	and	and	CCONJ
dpc-2345	4	10	phytochemistry	phytochemistry	NOUN
dpc-2345	4	11	,	,	PUNCT
dpc-2345	4	12	school	school	NOUN
dpc-2345	4	13	of	of	ADP
dpc-2345	4	14	pharmaceutical	pharmaceutical	ADJ
dpc-2345	4	15	education	education	NOUN
dpc-2345	4	16	and	and	CCONJ
dpc-2345	4	17	research	research	NOUN
dpc-2345	4	18	,	,	PUNCT
dpc-2345	4	19	jamia	jamia	PROPN
dpc-2345	4	20	hamdard	hamdard	PROPN
dpc-2345	4	21	,	,	PUNCT
dpc-2345	4	22	new	new	ADJ
dpc-2345	4	23	delhi	delhi	PROPN
dpc-2345	4	24	,	,	PUNCT
dpc-2345	4	25	india	india	PROPN
dpc-2345	4	26	2	2	NUM
dpc-2345	4	27	department	department	NOUN
dpc-2345	4	28	of	of	ADP
dpc-2345	4	29	pharmaceutics	pharmaceutic	NOUN
dpc-2345	4	30	,	,	PUNCT
dpc-2345	4	31	school	school	NOUN
dpc-2345	4	32	of	of	ADP
dpc-2345	4	33	pharmaceutical	pharmaceutical	ADJ
dpc-2345	4	34	education	education	NOUN
dpc-2345	4	35	and	and	CCONJ
dpc-2345	4	36	research	research	NOUN
dpc-2345	4	37	,	,	PUNCT
dpc-2345	4	38	jamia	jamia	PROPN
dpc-2345	4	39	hamdard	hamdard	PROPN
dpc-2345	4	40	,	,	PUNCT
dpc-2345	4	41	new	new	ADJ
dpc-2345	4	42	delhi	delhi	PROPN
dpc-2345	4	43	,	,	PUNCT
dpc-2345	4	44	india	india	PROPN
dpc-2345	4	45	key	key	ADJ
dpc-2345	4	46	words	word	NOUN
dpc-2345	4	47	:	:	PUNCT
dpc-2345	4	48	onychomycosis	onychomycosis	NOUN
dpc-2345	4	49	,	,	PUNCT
dpc-2345	4	50	transungual	transungual	ADJ
dpc-2345	4	51	,	,	PUNCT
dpc-2345	4	52	terpenes	terpene	NOUN
dpc-2345	4	53	,	,	PUNCT
dpc-2345	4	54	penetration	penetration	NOUN
dpc-2345	4	55	enhancer	enhancer	NOUN
dpc-2345	4	56	,	,	PUNCT
dpc-2345	4	57	terbinafine	terbinafine	NOUN
dpc-2345	4	58	,	,	PUNCT
dpc-2345	4	59	citation	citation	NOUN
dpc-2345	4	60	:	:	PUNCT
dpc-2345	4	61	gupta	gupta	PROPN
dpc-2345	4	62	i	i	PRON
dpc-2345	4	63	,	,	PUNCT
dpc-2345	4	64	adin	adin	PROPN
dpc-2345	4	65	s	s	PART
dpc-2345	4	66	n	n	CCONJ
dpc-2345	4	67	,	,	PUNCT
dpc-2345	4	68	aqil	aqil	PROPN
dpc-2345	4	69	m	m	PROPN
dpc-2345	4	70	,	,	PUNCT
dpc-2345	4	71	mujeeb	mujeeb	PROPN
dpc-2345	4	72	m	m	PROPN
dpc-2345	4	73	,	,	PUNCT
dpc-2345	4	74	sultana	sultana	PROPN
dpc-2345	4	75	y.	y.	PROPN
dpc-2345	4	76	investigation	investigation	NOUN
dpc-2345	4	77	on	on	ADP
dpc-2345	4	78	utility	utility	NOUN
dpc-2345	4	79	of	of	ADP
dpc-2345	4	80	some	some	DET
dpc-2345	4	81	novel	novel	ADJ
dpc-2345	4	82	terpenes	terpene	NOUN
dpc-2345	4	83	on	on	ADP
dpc-2345	4	84	transungual	transungual	ADJ
dpc-2345	4	85	delivery	delivery	NOUN
dpc-2345	4	86	of	of	ADP
dpc-2345	4	87	terbinafine	terbinafine	NOUN
dpc-2345	4	88	for	for	ADP
dpc-2345	4	89	the	the	DET
dpc-2345	4	90	management	management	NOUN
dpc-2345	4	91	of	of	ADP
dpc-2345	4	92	onychomycosis	onychomycosis	NOUN
dpc-2345	4	93	.	.	PUNCT
dpc-2345	5	1	dermatol	dermatol	NOUN
dpc-2345	5	2	pract	pract	PROPN
dpc-2345	5	3	concept	concept	NOUN
dpc-2345	5	4	.	.	PUNCT
dpc-2345	6	1	2022;12(4):e2022202	2022;12(4):e2022202	X
dpc-2345	6	2	.	.	PUNCT
dpc-2345	6	3	doi	doi	PROPN
dpc-2345	6	4	:	:	PUNCT
dpc-2345	6	5	https://doi.org/10.5826/dpc.1204a202	https://doi.org/10.5826/dpc.1204a202	NOUN
dpc-2345	6	6	accepted	accept	VERB
dpc-2345	6	7	:	:	PUNCT
dpc-2345	6	8	february	february	PROPN
dpc-2345	6	9	21	21	NUM
dpc-2345	6	10	,	,	PUNCT
dpc-2345	6	11	2022	2022	NUM
dpc-2345	6	12	;	;	PUNCT
dpc-2345	6	13	published	publish	VERB
dpc-2345	6	14	:	:	PUNCT
dpc-2345	6	15	october	october	PROPN
dpc-2345	6	16	2022	2022	NUM
dpc-2345	7	1	copyright	copyright	NOUN
dpc-2345	7	2	:	:	PUNCT
dpc-2345	7	3	©	©	PROPN
dpc-2345	7	4	2022	2022	NUM
dpc-2345	7	5	gupta	gupta	PROPN
dpc-2345	7	6	et	et	PROPN
dpc-2345	7	7	al	al	PROPN
dpc-2345	7	8	.	.	PUNCT
dpc-2345	8	1	this	this	PRON
dpc-2345	8	2	is	be	AUX
dpc-2345	8	3	an	an	DET
dpc-2345	8	4	open	open	ADJ
dpc-2345	8	5	-	-	PUNCT
dpc-2345	8	6	access	access	NOUN
dpc-2345	8	7	article	article	NOUN
dpc-2345	8	8	distributed	distribute	VERB
dpc-2345	8	9	under	under	ADP
dpc-2345	8	10	the	the	DET
dpc-2345	8	11	terms	term	NOUN
dpc-2345	8	12	of	of	ADP
dpc-2345	8	13	the	the	DET
dpc-2345	8	14	creative	creative	ADJ
dpc-2345	8	15	commons	common	NOUN
dpc-2345	8	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-2345	8	17	license	license	NOUN
dpc-2345	8	18	(	(	PUNCT
dpc-2345	8	19	by	by	ADP
dpc-2345	8	20	-	-	PUNCT
dpc-2345	8	21	nc-4.0	nc-4.0	NOUN
dpc-2345	8	22	)	)	PUNCT
dpc-2345	8	23	,	,	PUNCT
dpc-2345	8	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-2345	8	25	,	,	PUNCT
dpc-2345	8	26	which	which	PRON
dpc-2345	8	27	permits	permit	VERB
dpc-2345	8	28	unrestricted	unrestricted	ADJ
dpc-2345	8	29	noncommercial	noncommercial	ADJ
dpc-2345	8	30	use	use	NOUN
dpc-2345	8	31	,	,	PUNCT
dpc-2345	8	32	distribution	distribution	NOUN
dpc-2345	8	33	,	,	PUNCT
dpc-2345	8	34	and	and	CCONJ
dpc-2345	8	35	reproduction	reproduction	NOUN
dpc-2345	8	36	in	in	ADP
dpc-2345	8	37	any	any	DET
dpc-2345	8	38	medium	medium	NOUN
dpc-2345	8	39	,	,	PUNCT
dpc-2345	8	40	provided	provide	VERB
dpc-2345	8	41	the	the	DET
dpc-2345	8	42	original	original	ADJ
dpc-2345	8	43	authors	author	NOUN
dpc-2345	8	44	and	and	CCONJ
dpc-2345	8	45	source	source	NOUN
dpc-2345	8	46	are	be	AUX
dpc-2345	8	47	credited	credit	VERB
dpc-2345	8	48	.	.	PUNCT
dpc-2345	9	1	funding	funding	NOUN
dpc-2345	9	2	:	:	PUNCT
dpc-2345	9	3	none	none	NOUN
dpc-2345	9	4	.	.	PUNCT
dpc-2345	10	1	competing	compete	VERB
dpc-2345	10	2	interests	interest	NOUN
dpc-2345	10	3	:	:	PUNCT
dpc-2345	10	4	none	none	NOUN
dpc-2345	10	5	.	.	PUNCT
dpc-2345	11	1	authorship	authorship	NOUN
dpc-2345	11	2	:	:	PUNCT
dpc-2345	11	3	both	both	CCONJ
dpc-2345	11	4	isha	isha	PROPN
dpc-2345	11	5	gupta	gupta	PROPN
dpc-2345	11	6	and	and	CCONJ
dpc-2345	11	7	syeda	syeda	PROPN
dpc-2345	11	8	nashvia	nashvia	PROPN
dpc-2345	11	9	adin	adin	PROPN
dpc-2345	11	10	have	have	VERB
dpc-2345	11	11	equal	equal	ADJ
dpc-2345	11	12	contribution	contribution	NOUN
dpc-2345	11	13	in	in	ADP
dpc-2345	11	14	this	this	DET
dpc-2345	11	15	article	article	NOUN
dpc-2345	11	16	and	and	CCONJ
dpc-2345	11	17	should	should	AUX
dpc-2345	11	18	be	be	AUX
dpc-2345	11	19	considered	consider	VERB
dpc-2345	11	20	joint	joint	ADJ
dpc-2345	11	21	first	first	ADJ
dpc-2345	11	22	author	author	NOUN
dpc-2345	11	23	.	.	PUNCT
dpc-2345	12	1	corresponding	correspond	VERB
dpc-2345	12	2	author	author	NOUN
dpc-2345	12	3	:	:	PUNCT
dpc-2345	13	1	mohd	mohd	PROPN
dpc-2345	13	2	.	.	PUNCT
dpc-2345	14	1	aqil	aqil	PROPN
dpc-2345	14	2	,	,	PUNCT
dpc-2345	14	3	associate	associate	NOUN
dpc-2345	14	4	professor	professor	NOUN
dpc-2345	14	5	,	,	PUNCT
dpc-2345	14	6	department	department	NOUN
dpc-2345	14	7	of	of	ADP
dpc-2345	14	8	pharmaceutics	pharmaceutic	NOUN
dpc-2345	14	9	,	,	PUNCT
dpc-2345	14	10	school	school	NOUN
dpc-2345	14	11	of	of	ADP
dpc-2345	14	12	pharmaceutical	pharmaceutical	ADJ
dpc-2345	14	13	education	education	NOUN
dpc-2345	14	14	and	and	CCONJ
dpc-2345	14	15	research	research	NOUN
dpc-2345	14	16	,	,	PUNCT
dpc-2345	14	17	jamia	jamia	PROPN
dpc-2345	14	18	hamdard	hamdard	PROPN
dpc-2345	14	19	(	(	PUNCT
dpc-2345	14	20	deemed	deem	VERB
dpc-2345	14	21	university	university	NOUN
dpc-2345	14	22	)	)	PUNCT
dpc-2345	14	23	,	,	PUNCT
dpc-2345	14	24	new	new	PROPN
dpc-2345	14	25	delhi	delhi	PROPN
dpc-2345	14	26	,	,	PUNCT
dpc-2345	14	27	india-110062	india-110062	NOUN
dpc-2345	14	28	,	,	PUNCT
dpc-2345	14	29	contact	contact	NOUN
dpc-2345	14	30	:	:	PUNCT
dpc-2345	14	31	+91	+91	NOUN
dpc-2345	14	32	-	-	PUNCT
dpc-2345	14	33	9811798725	9811798725	NUM
dpc-2345	14	34	,	,	PUNCT
dpc-2345	14	35	e	e	NOUN
dpc-2345	14	36	-	-	NOUN
dpc-2345	14	37	mail	mail	NOUN
dpc-2345	14	38	:	:	PUNCT
dpc-2345	15	1	aqilmalik@yahoo.com	aqilmalik@yahoo.com	PROPN
dpc-2345	15	2	introduction	introduction	NOUN
dpc-2345	15	3	:	:	PUNCT
dpc-2345	15	4	onychomycosis	onychomycosis	NOUN
dpc-2345	15	5	is	be	AUX
dpc-2345	15	6	a	a	DET
dpc-2345	15	7	fungal	fungal	ADJ
dpc-2345	15	8	disorder	disorder	NOUN
dpc-2345	15	9	of	of	ADP
dpc-2345	15	10	the	the	DET
dpc-2345	15	11	nail	nail	NOUN
dpc-2345	15	12	which	which	PRON
dpc-2345	15	13	afflicts	afflict	VERB
dpc-2345	15	14	5	5	NUM
dpc-2345	15	15	%	%	NOUN
dpc-2345	15	16	of	of	ADP
dpc-2345	15	17	the	the	DET
dpc-2345	15	18	population	population	NOUN
dpc-2345	15	19	worldwide	worldwide	ADV
dpc-2345	15	20	.	.	PUNCT
dpc-2345	16	1	the	the	DET
dpc-2345	16	2	disease	disease	NOUN
dpc-2345	16	3	is	be	AUX
dpc-2345	16	4	strenuous	strenuous	ADJ
dpc-2345	16	5	to	to	PART
dpc-2345	16	6	cure	cure	VERB
dpc-2345	16	7	as	as	SCONJ
dpc-2345	16	8	it	it	PRON
dpc-2345	16	9	is	be	AUX
dpc-2345	16	10	chronic	chronic	ADJ
dpc-2345	16	11	,	,	PUNCT
dpc-2345	16	12	hard	hard	ADJ
dpc-2345	16	13	to	to	PART
dpc-2345	16	14	eliminate	eliminate	VERB
dpc-2345	16	15	and	and	CCONJ
dpc-2345	16	16	tends	tend	VERB
dpc-2345	16	17	to	to	PART
dpc-2345	16	18	recur	recur	VERB
dpc-2345	16	19	.	.	PUNCT
dpc-2345	17	1	topical	topical	ADJ
dpc-2345	17	2	therapy	therapy	NOUN
dpc-2345	17	3	is	be	AUX
dpc-2345	17	4	at	at	ADP
dpc-2345	17	5	the	the	DET
dpc-2345	17	6	forefront	forefront	NOUN
dpc-2345	17	7	for	for	ADP
dpc-2345	17	8	the	the	DET
dpc-2345	17	9	treatment	treatment	NOUN
dpc-2345	17	10	of	of	ADP
dpc-2345	17	11	many	many	ADJ
dpc-2345	17	12	disorders	disorder	NOUN
dpc-2345	17	13	of	of	ADP
dpc-2345	17	14	nail	nail	NOUN
dpc-2345	17	15	.	.	PUNCT
dpc-2345	18	1	however	however	ADV
dpc-2345	18	2	,	,	PUNCT
dpc-2345	18	3	the	the	DET
dpc-2345	18	4	success	success	NOUN
dpc-2345	18	5	rate	rate	NOUN
dpc-2345	18	6	of	of	ADP
dpc-2345	18	7	topical	topical	ADJ
dpc-2345	18	8	therapy	therapy	NOUN
dpc-2345	18	9	has	have	AUX
dpc-2345	18	10	been	be	AUX
dpc-2345	18	11	halted	halt	VERB
dpc-2345	18	12	owing	owe	VERB
dpc-2345	18	13	to	to	ADP
dpc-2345	18	14	the	the	DET
dpc-2345	18	15	poor	poor	ADJ
dpc-2345	18	16	permeation	permeation	NOUN
dpc-2345	18	17	of	of	ADP
dpc-2345	18	18	topical	topical	ADJ
dpc-2345	18	19	therapeutics	therapeutic	NOUN
dpc-2345	18	20	across	across	ADP
dpc-2345	18	21	densely	densely	ADV
dpc-2345	18	22	keratinized	keratinize	VERB
dpc-2345	18	23	nail	nail	NOUN
dpc-2345	18	24	barrier	barrier	NOUN
dpc-2345	18	25	.	.	PUNCT
dpc-2345	19	1	therefore	therefore	ADV
dpc-2345	19	2	,	,	PUNCT
dpc-2345	19	3	ungual	ungual	ADJ
dpc-2345	19	4	drug	drug	NOUN
dpc-2345	19	5	permeation	permeation	NOUN
dpc-2345	19	6	must	must	AUX
dpc-2345	19	7	be	be	AUX
dpc-2345	19	8	improved	improve	VERB
dpc-2345	19	9	for	for	ADP
dpc-2345	19	10	an	an	DET
dpc-2345	19	11	effective	effective	ADJ
dpc-2345	19	12	topical	topical	ADJ
dpc-2345	19	13	therapy	therapy	NOUN
dpc-2345	19	14	.	.	PUNCT
dpc-2345	20	1	an	an	DET
dpc-2345	20	2	approach	approach	NOUN
dpc-2345	20	3	to	to	PART
dpc-2345	20	4	achieve	achieve	VERB
dpc-2345	20	5	this	this	DET
dpc-2345	20	6	goal	goal	NOUN
dpc-2345	20	7	would	would	AUX
dpc-2345	20	8	be	be	AUX
dpc-2345	20	9	the	the	DET
dpc-2345	20	10	use	use	NOUN
dpc-2345	20	11	of	of	ADP
dpc-2345	20	12	terpenes	terpene	NOUN
dpc-2345	20	13	from	from	ADP
dpc-2345	20	14	natural	natural	ADJ
dpc-2345	20	15	sources	source	NOUN
dpc-2345	20	16	as	as	ADP
dpc-2345	20	17	potential	potential	ADJ
dpc-2345	20	18	penetration	penetration	NOUN
dpc-2345	20	19	enhancers	enhancer	NOUN
dpc-2345	20	20	.	.	PUNCT
dpc-2345	21	1	objective	objective	NOUN
dpc-2345	21	2	:	:	PUNCT
dpc-2345	21	3	this	this	DET
dpc-2345	21	4	study	study	NOUN
dpc-2345	21	5	is	be	AUX
dpc-2345	21	6	aimed	aim	VERB
dpc-2345	21	7	to	to	PART
dpc-2345	21	8	explore	explore	VERB
dpc-2345	21	9	the	the	DET
dpc-2345	21	10	effectiveness	effectiveness	NOUN
dpc-2345	21	11	of	of	ADP
dpc-2345	21	12	some	some	DET
dpc-2345	21	13	novel	novel	ADJ
dpc-2345	21	14	terpenes	terpene	NOUN
dpc-2345	21	15	as	as	ADP
dpc-2345	21	16	potential	potential	ADJ
dpc-2345	21	17	penetration	penetration	NOUN
dpc-2345	21	18	enhancers	enhancer	NOUN
dpc-2345	21	19	on	on	ADP
dpc-2345	21	20	transungual	transungual	ADJ
dpc-2345	21	21	delivery	delivery	NOUN
dpc-2345	21	22	of	of	ADP
dpc-2345	21	23	terbinafine	terbinafine	NOUN
dpc-2345	21	24	.	.	PUNCT
dpc-2345	22	1	methods	method	NOUN
dpc-2345	22	2	:	:	PUNCT
dpc-2345	22	3	ex	ex	ADJ
dpc-2345	22	4	-	-	ADJ
dpc-2345	22	5	vivo	vivo	ADJ
dpc-2345	22	6	permeation	permeation	NOUN
dpc-2345	22	7	studies	study	NOUN
dpc-2345	22	8	were	be	AUX
dpc-2345	22	9	performed	perform	VERB
dpc-2345	22	10	by	by	ADP
dpc-2345	22	11	sopping	sop	VERB
dpc-2345	22	12	the	the	DET
dpc-2345	22	13	nail	nail	NOUN
dpc-2345	22	14	clippings	clipping	NOUN
dpc-2345	22	15	of	of	ADP
dpc-2345	22	16	healthy	healthy	ADJ
dpc-2345	22	17	human	human	ADJ
dpc-2345	22	18	volunteers	volunteer	NOUN
dpc-2345	22	19	in	in	ADP
dpc-2345	22	20	control	control	NOUN
dpc-2345	22	21	and	and	CCONJ
dpc-2345	22	22	working	work	VERB
dpc-2345	22	23	solutions	solution	NOUN
dpc-2345	22	24	containing	contain	VERB
dpc-2345	22	25	terbinafine	terbinafine	NOUN
dpc-2345	22	26	(	(	PUNCT
dpc-2345	22	27	5mg	5mg	NOUN
dpc-2345	22	28	/	/	SYM
dpc-2345	22	29	ml	ml	NOUN
dpc-2345	22	30	)	)	PUNCT
dpc-2345	22	31	per	per	X
dpc-2345	22	32	se	se	X
dpc-2345	22	33	and	and	CCONJ
dpc-2345	22	34	terbinafine	terbinafine	ADJ
dpc-2345	22	35	(	(	PUNCT
dpc-2345	22	36	5mg	5mg	NOUN
dpc-2345	22	37	/	/	SYM
dpc-2345	22	38	ml	ml	NOUN
dpc-2345	22	39	)	)	PUNCT
dpc-2345	22	40	with	with	ADP
dpc-2345	22	41	6	6	NUM
dpc-2345	22	42	%	%	NOUN
dpc-2345	22	43	of	of	ADP
dpc-2345	22	44	each	each	DET
dpc-2345	22	45	terpenes	terpene	NOUN
dpc-2345	22	46	including	include	VERB
dpc-2345	22	47	lavandulol	lavandulol	NOUN
dpc-2345	22	48	,	,	PUNCT
dpc-2345	22	49	safranal	safranal	ADJ
dpc-2345	22	50	,	,	PUNCT
dpc-2345	22	51	rose	rise	VERB
dpc-2345	22	52	oxide	oxide	NOUN
dpc-2345	22	53	,	,	PUNCT
dpc-2345	22	54	limonene	limonene	NOUN
dpc-2345	22	55	,	,	PUNCT
dpc-2345	22	56	3	3	NUM
dpc-2345	22	57	-	-	PUNCT
dpc-2345	22	58	methyl-2butene-1	methyl-2butene-1	NOUN
dpc-2345	22	59	-	-	NOUN
dpc-2345	22	60	ol	ol	ADJ
dpc-2345	22	61	,	,	PUNCT
dpc-2345	22	62	and	and	CCONJ
dpc-2345	22	63	linalool	linalool	NOUN
dpc-2345	22	64	respectively	respectively	ADV
dpc-2345	22	65	for	for	ADP
dpc-2345	22	66	48	48	NUM
dpc-2345	22	67	hours	hour	NOUN
dpc-2345	22	68	.	.	PUNCT
dpc-2345	23	1	the	the	DET
dpc-2345	23	2	terbinafine	terbinafine	ADJ
dpc-2345	23	3	concentration	concentration	NOUN
dpc-2345	23	4	in	in	ADP
dpc-2345	23	5	nail	nail	NOUN
dpc-2345	23	6	samples	sample	NOUN
dpc-2345	23	7	was	be	AUX
dpc-2345	23	8	determined	determine	VERB
dpc-2345	23	9	using	use	VERB
dpc-2345	23	10	a	a	DET
dpc-2345	23	11	hplc	hplc	NOUN
dpc-2345	23	12	(	(	PUNCT
dpc-2345	23	13	high	high	ADJ
dpc-2345	23	14	performance	performance	NOUN
dpc-2345	23	15	liquid	liquid	NOUN
dpc-2345	23	16	chromatography	chromatography	NOUN
dpc-2345	23	17	method	method	NOUN
dpc-2345	23	18	.	.	PUNCT
dpc-2345	24	1	results	result	NOUN
dpc-2345	24	2	:	:	PUNCT
dpc-2345	24	3	statistical	statistical	ADJ
dpc-2345	24	4	analysis	analysis	NOUN
dpc-2345	24	5	showed	show	VERB
dpc-2345	24	6	that	that	SCONJ
dpc-2345	24	7	studied	study	VERB
dpc-2345	24	8	terpenes	terpene	NOUN
dpc-2345	24	9	increase	increase	VERB
dpc-2345	24	10	transungual	transungual	ADJ
dpc-2345	24	11	penetration	penetration	NOUN
dpc-2345	24	12	of	of	ADP
dpc-2345	24	13	terbinafine	terbinafine	NOUN
dpc-2345	24	14	in	in	ADP
dpc-2345	24	15	the	the	DET
dpc-2345	24	16	following	follow	VERB
dpc-2345	24	17	order	order	NOUN
dpc-2345	24	18	:	:	PUNCT
dpc-2345	24	19	linalool	linalool	NOUN
dpc-2345	24	20	>	>	X
dpc-2345	24	21	rose	rise	VERB
dpc-2345	24	22	oxide	oxide	NOUN
dpc-2345	24	23	>	>	X
dpc-2345	24	24	3	3	NUM
dpc-2345	24	25	-	-	PUNCT
dpc-2345	24	26	methyl-2	methyl-2	NOUN
dpc-2345	24	27	-	-	PUNCT
dpc-2345	24	28	butene-1	butene-1	NOUN
dpc-2345	24	29	-	-	PUNCT
dpc-2345	24	30	ol	ol	NOUN
dpc-2345	24	31	>	>	X
dpc-2345	24	32	safranal	safranal	PROPN
dpc-2345	24	33	>	>	X
dpc-2345	24	34	limonene	limonene	PROPN
dpc-2345	24	35	>	>	X
dpc-2345	24	36	lavandulol	lavandulol	PROPN
dpc-2345	24	37	acetate	acetate	PROPN
dpc-2345	24	38	.	.	PUNCT
dpc-2345	25	1	accordingly	accordingly	ADV
dpc-2345	25	2	,	,	PUNCT
dpc-2345	25	3	linalool	linalool	NOUN
dpc-2345	25	4	was	be	AUX
dpc-2345	25	5	found	find	VERB
dpc-2345	25	6	to	to	PART
dpc-2345	25	7	be	be	AUX
dpc-2345	25	8	the	the	DET
dpc-2345	25	9	most	most	ADV
dpc-2345	25	10	effective	effective	ADJ
dpc-2345	25	11	penetration	penetration	NOUN
dpc-2345	25	12	enhancer	enhancer	NOUN
dpc-2345	25	13	for	for	ADP
dpc-2345	25	14	the	the	DET
dpc-2345	25	15	transungual	transungual	ADJ
dpc-2345	25	16	delivery	delivery	NOUN
dpc-2345	25	17	of	of	ADP
dpc-2345	25	18	terbinafine	terbinafine	NOUN
dpc-2345	25	19	.	.	PUNCT
dpc-2345	26	1	conclusions	conclusion	NOUN
dpc-2345	26	2	:	:	PUNCT
dpc-2345	26	3	it	it	PRON
dpc-2345	26	4	is	be	AUX
dpc-2345	26	5	concluded	conclude	VERB
dpc-2345	26	6	that	that	SCONJ
dpc-2345	26	7	linalool	linalool	NOUN
dpc-2345	26	8	can	can	AUX
dpc-2345	26	9	be	be	AUX
dpc-2345	26	10	used	use	VERB
dpc-2345	26	11	as	as	ADP
dpc-2345	26	12	safe	safe	ADJ
dpc-2345	26	13	and	and	CCONJ
dpc-2345	26	14	potential	potential	ADJ
dpc-2345	26	15	penetration	penetration	NOUN
dpc-2345	26	16	enhancer	enhancer	NOUN
dpc-2345	26	17	for	for	ADP
dpc-2345	26	18	enhancing	enhance	VERB
dpc-2345	26	19	the	the	DET
dpc-2345	26	20	transungual	transungual	ADJ
dpc-2345	26	21	delivery	delivery	NOUN
dpc-2345	26	22	of	of	ADP
dpc-2345	26	23	terbinafine	terbinafine	NOUN
dpc-2345	26	24	for	for	ADP
dpc-2345	26	25	onychomycosis	onychomycosis	NOUN
dpc-2345	26	26	.	.	PUNCT
dpc-2345	27	1	abstract	abstract	ADJ
dpc-2345	27	2	2	2	NUM
dpc-2345	27	3	review	review	NOUN
dpc-2345	27	4	|	|	ADV
dpc-2345	27	5	dermatol	dermatol	ADJ
dpc-2345	27	6	pract	pract	NOUN
dpc-2345	27	7	concept	concept	NOUN
dpc-2345	27	8	.	.	PUNCT
dpc-2345	28	1	2022;12(4):e2022202	2022;12(4):e2022202	NUM
dpc-2345	28	2	introduction	introduction	NOUN
dpc-2345	28	3	onychomycosis	onychomycosis	NOUN
dpc-2345	28	4	is	be	AUX
dpc-2345	28	5	the	the	DET
dpc-2345	28	6	most	most	ADV
dpc-2345	28	7	prevalent	prevalent	ADJ
dpc-2345	28	8	fungal	fungal	ADJ
dpc-2345	28	9	disorder	disorder	NOUN
dpc-2345	28	10	of	of	ADP
dpc-2345	28	11	the	the	DET
dpc-2345	28	12	nails	nail	NOUN
dpc-2345	28	13	attributable	attributable	ADJ
dpc-2345	28	14	to	to	ADP
dpc-2345	28	15	yeasts	yeast	NOUN
dpc-2345	28	16	(	(	PUNCT
dpc-2345	28	17	candida	candida	NOUN
dpc-2345	28	18	albicans	albican	NOUN
dpc-2345	28	19	and	and	CCONJ
dpc-2345	28	20	other	other	ADJ
dpc-2345	28	21	candida	candida	PROPN
dpc-2345	28	22	species	specie	NOUN
dpc-2345	28	23	)	)	PUNCT
dpc-2345	28	24	,	,	PUNCT
dpc-2345	28	25	non	non	ADJ
dpc-2345	28	26	-	-	ADJ
dpc-2345	28	27	dermatophyte	dermatophyte	ADJ
dpc-2345	28	28	molds	mold	NOUN
dpc-2345	28	29	(	(	PUNCT
dpc-2345	28	30	scytalidium	scytalidium	NOUN
dpc-2345	28	31	hyalinum	hyalinum	NOUN
dpc-2345	28	32	,	,	PUNCT
dpc-2345	28	33	scopularicpsis	scopularicpsis	NOUN
dpc-2345	28	34	brevicaulis	brevicauli	NOUN
dpc-2345	28	35	,	,	PUNCT
dpc-2345	28	36	acremonium	acremonium	NOUN
dpc-2345	28	37	sp	sp	NOUN
dpc-2345	28	38	.	.	PROPN
dpc-2345	28	39	,	,	PUNCT
dpc-2345	28	40	aspergillus	aspergillus	PROPN
dpc-2345	28	41	sp	sp	PROPN
dpc-2345	28	42	.	.	PROPN
dpc-2345	28	43	,	,	PUNCT
dpc-2345	28	44	s.dimidiatum	s.dimidiatum	NOUN
dpc-2345	28	45	)	)	PUNCT
dpc-2345	28	46	,	,	PUNCT
dpc-2345	28	47	and	and	CCONJ
dpc-2345	28	48	dermatophytes	dermatophyte	VERB
dpc-2345	28	49	(	(	PUNCT
dpc-2345	28	50	trichophyton	trichophyton	NOUN
dpc-2345	28	51	rubrum	rubrum	NOUN
dpc-2345	28	52	,	,	PUNCT
dpc-2345	28	53	t.	t.	NOUN
dpc-2345	28	54	krajdenii	krajdenii	PROPN
dpc-2345	28	55	,	,	PUNCT
dpc-2345	28	56	t.	t.	PROPN
dpc-2345	28	57	mentagrophytes	mentagrophyte	NOUN
dpc-2345	28	58	,	,	PUNCT
dpc-2345	28	59	epidermophyton	epidermophyton	NOUN
dpc-2345	28	60	floccosum	floccosum	NOUN
dpc-2345	28	61	)	)	PUNCT
dpc-2345	29	1	[	[	X
dpc-2345	29	2	1	1	NUM
dpc-2345	29	3	]	]	PUNCT
dpc-2345	29	4	.	.	PUNCT
dpc-2345	30	1	due	due	ADP
dpc-2345	30	2	to	to	ADP
dpc-2345	30	3	this	this	DET
dpc-2345	30	4	infection	infection	NOUN
dpc-2345	30	5	,	,	PUNCT
dpc-2345	30	6	the	the	DET
dpc-2345	30	7	patients	patient	NOUN
dpc-2345	30	8	experience	experience	VERB
dpc-2345	30	9	a	a	DET
dpc-2345	30	10	prodrome	prodrome	NOUN
dpc-2345	30	11	of	of	ADP
dpc-2345	30	12	nail	nail	NOUN
dpc-2345	30	13	plate	plate	NOUN
dpc-2345	30	14	thickening	thickening	NOUN
dpc-2345	30	15	,	,	PUNCT
dpc-2345	30	16	onycholysis	onycholysis	NOUN
dpc-2345	30	17	,	,	PUNCT
dpc-2345	30	18	and	and	CCONJ
dpc-2345	30	19	nail	nail	NOUN
dpc-2345	30	20	discoloration	discoloration	NOUN
dpc-2345	30	21	.	.	PUNCT
dpc-2345	31	1	the	the	DET
dpc-2345	31	2	afflicted	afflict	VERB
dpc-2345	31	3	patients	patient	NOUN
dpc-2345	31	4	experience	experience	VERB
dpc-2345	31	5	paresthesia	paresthesia	PROPN
dpc-2345	31	6	,	,	PUNCT
dpc-2345	31	7	local	local	ADJ
dpc-2345	31	8	pain	pain	NOUN
dpc-2345	31	9	,	,	PUNCT
dpc-2345	31	10	and	and	CCONJ
dpc-2345	31	11	reduced	reduce	VERB
dpc-2345	31	12	quality	quality	NOUN
dpc-2345	31	13	of	of	ADP
dpc-2345	31	14	life	life	NOUN
dpc-2345	31	15	.	.	PUNCT
dpc-2345	32	1	the	the	DET
dpc-2345	32	2	abnormal	abnormal	ADJ
dpc-2345	32	3	appearance	appearance	NOUN
dpc-2345	32	4	of	of	ADP
dpc-2345	32	5	the	the	DET
dpc-2345	32	6	nails	nail	NOUN
dpc-2345	32	7	may	may	AUX
dpc-2345	32	8	plague	plague	VERB
dpc-2345	32	9	the	the	DET
dpc-2345	32	10	daily	daily	ADJ
dpc-2345	32	11	activities	activity	NOUN
dpc-2345	32	12	and	and	CCONJ
dpc-2345	32	13	stigmatize	stigmatize	VERB
dpc-2345	32	14	social	social	ADJ
dpc-2345	32	15	life	life	NOUN
dpc-2345	32	16	of	of	ADP
dpc-2345	32	17	affected	affect	VERB
dpc-2345	32	18	persons	person	NOUN
dpc-2345	32	19	[	[	X
dpc-2345	32	20	2	2	NUM
dpc-2345	32	21	]	]	PUNCT
dpc-2345	32	22	.	.	PUNCT
dpc-2345	33	1	onychomycosis	onychomycosis	NOUN
dpc-2345	33	2	progression	progression	NOUN
dpc-2345	33	3	increases	increase	VERB
dpc-2345	33	4	with	with	ADP
dpc-2345	33	5	simultaneous	simultaneous	ADJ
dpc-2345	33	6	inhabitation	inhabitation	NOUN
dpc-2345	33	7	of	of	ADP
dpc-2345	33	8	other	other	ADJ
dpc-2345	33	9	conditions	condition	NOUN
dpc-2345	33	10	like	like	ADP
dpc-2345	33	11	hiv	hiv	PROPN
dpc-2345	33	12	,	,	PUNCT
dpc-2345	33	13	poor	poor	ADJ
dpc-2345	33	14	peripheral	peripheral	ADJ
dpc-2345	33	15	circulation	circulation	NOUN
dpc-2345	33	16	,	,	PUNCT
dpc-2345	33	17	diabetes	diabetes	NOUN
dpc-2345	33	18	,	,	PUNCT
dpc-2345	33	19	and	and	CCONJ
dpc-2345	33	20	immunosuppression	immunosuppression	NOUN
dpc-2345	33	21	[	[	X
dpc-2345	33	22	1	1	NUM
dpc-2345	33	23	]	]	PUNCT
dpc-2345	33	24	.	.	PUNCT
dpc-2345	34	1	the	the	DET
dpc-2345	34	2	onychomycosis	onychomycosis	NOUN
dpc-2345	34	3	treatment	treatment	NOUN
dpc-2345	34	4	always	always	ADV
dpc-2345	34	5	remains	remain	VERB
dpc-2345	34	6	challenging	challenge	VERB
dpc-2345	34	7	due	due	ADP
dpc-2345	34	8	to	to	ADP
dpc-2345	34	9	the	the	DET
dpc-2345	34	10	thick	thick	ADJ
dpc-2345	34	11	impermeable	impermeable	ADJ
dpc-2345	34	12	property	property	NOUN
dpc-2345	34	13	of	of	ADP
dpc-2345	34	14	the	the	DET
dpc-2345	34	15	nail	nail	NOUN
dpc-2345	34	16	and	and	CCONJ
dpc-2345	35	1	profound	profound	ADJ
dpc-2345	35	2	infection	infection	NOUN
dpc-2345	35	3	[	[	X
dpc-2345	35	4	3	3	NUM
dpc-2345	35	5	]	]	PUNCT
dpc-2345	35	6	.	.	PUNCT
dpc-2345	36	1	however	however	ADV
dpc-2345	36	2	,	,	PUNCT
dpc-2345	36	3	oral	oral	ADJ
dpc-2345	36	4	treatment	treatment	NOUN
dpc-2345	36	5	therapy	therapy	NOUN
dpc-2345	36	6	remains	remain	VERB
dpc-2345	36	7	the	the	DET
dpc-2345	36	8	priority	priority	NOUN
dpc-2345	36	9	for	for	ADP
dpc-2345	36	10	the	the	DET
dpc-2345	36	11	affected	affect	VERB
dpc-2345	36	12	patients	patient	NOUN
dpc-2345	36	13	due	due	ADP
dpc-2345	36	14	to	to	ADP
dpc-2345	36	15	the	the	DET
dpc-2345	36	16	accessibility	accessibility	NOUN
dpc-2345	36	17	and	and	CCONJ
dpc-2345	36	18	efficacy	efficacy	NOUN
dpc-2345	36	19	of	of	ADP
dpc-2345	36	20	oral	oral	ADJ
dpc-2345	36	21	therapeutics	therapeutic	NOUN
dpc-2345	36	22	[	[	X
dpc-2345	36	23	2	2	NUM
dpc-2345	36	24	]	]	PUNCT
dpc-2345	36	25	.	.	PUNCT
dpc-2345	37	1	the	the	DET
dpc-2345	37	2	oral	oral	ADJ
dpc-2345	37	3	treatment	treatment	NOUN
dpc-2345	37	4	includes	include	VERB
dpc-2345	37	5	anti	anti	ADJ
dpc-2345	37	6	-	-	ADJ
dpc-2345	37	7	fungal	fungal	ADJ
dpc-2345	37	8	drugs	drug	NOUN
dpc-2345	37	9	from	from	ADP
dpc-2345	37	10	allylamine	allylamine	NOUN
dpc-2345	37	11	and	and	CCONJ
dpc-2345	37	12	azole	azole	PROPN
dpc-2345	37	13	classes	class	NOUN
dpc-2345	37	14	.	.	PUNCT
dpc-2345	38	1	the	the	DET
dpc-2345	38	2	azole	azole	ADJ
dpc-2345	38	3	class	class	NOUN
dpc-2345	38	4	includes	include	VERB
dpc-2345	38	5	ketoconazole	ketoconazole	NOUN
dpc-2345	38	6	,	,	PUNCT
dpc-2345	38	7	fluconazole	fluconazole	NOUN
dpc-2345	38	8	and	and	CCONJ
dpc-2345	38	9	itraconazole	itraconazole	NOUN
dpc-2345	38	10	and	and	CCONJ
dpc-2345	38	11	the	the	DET
dpc-2345	38	12	allylamine	allylamine	NOUN
dpc-2345	38	13	class	class	NOUN
dpc-2345	38	14	includes	include	VERB
dpc-2345	38	15	terbinafine	terbinafine	NOUN
dpc-2345	38	16	wherein	wherein	ADJ
dpc-2345	38	17	itraconazole	itraconazole	NOUN
dpc-2345	38	18	and	and	CCONJ
dpc-2345	38	19	terbinafine	terbinafine	NOUN
dpc-2345	38	20	are	be	AUX
dpc-2345	38	21	us	we	PRON
dpc-2345	38	22	fda	fda	PROPN
dpc-2345	38	23	approved	approve	VERB
dpc-2345	38	24	medications	medication	NOUN
dpc-2345	38	25	for	for	ADP
dpc-2345	38	26	onychomycosis	onychomycosis	NOUN
dpc-2345	38	27	treatment	treatment	NOUN
dpc-2345	38	28	[	[	X
dpc-2345	38	29	4	4	NUM
dpc-2345	38	30	-	-	SYM
dpc-2345	38	31	6	6	NUM
dpc-2345	38	32	]	]	PUNCT
dpc-2345	38	33	.	.	PUNCT
dpc-2345	39	1	terbinafine	terbinafine	NOUN
dpc-2345	39	2	excels	excel	VERB
dpc-2345	39	3	over	over	ADP
dpc-2345	39	4	itraconazole	itraconazole	NOUN
dpc-2345	39	5	due	due	ADP
dpc-2345	39	6	to	to	ADP
dpc-2345	39	7	higher	high	ADJ
dpc-2345	39	8	cure	cure	NOUN
dpc-2345	39	9	rate	rate	NOUN
dpc-2345	39	10	and	and	CCONJ
dpc-2345	39	11	fewer	few	ADJ
dpc-2345	39	12	drug	drug	NOUN
dpc-2345	39	13	interactions	interaction	NOUN
dpc-2345	39	14	.	.	PUNCT
dpc-2345	40	1	however	however	ADV
dpc-2345	40	2	,	,	PUNCT
dpc-2345	40	3	their	their	PRON
dpc-2345	40	4	effectiveness	effectiveness	NOUN
dpc-2345	40	5	is	be	AUX
dpc-2345	40	6	defined	define	VERB
dpc-2345	40	7	/	/	SYM
dpc-2345	40	8	constrained	constrain	VERB
dpc-2345	40	9	due	due	ADP
dpc-2345	40	10	to	to	ADP
dpc-2345	40	11	their	their	PRON
dpc-2345	40	12	limited	limited	ADJ
dpc-2345	40	13	availability	availability	NOUN
dpc-2345	40	14	at	at	ADP
dpc-2345	40	15	the	the	DET
dpc-2345	40	16	site	site	NOUN
dpc-2345	40	17	of	of	ADP
dpc-2345	40	18	action	action	NOUN
dpc-2345	40	19	,	,	PUNCT
dpc-2345	40	20	which	which	PRON
dpc-2345	40	21	further	far	ADV
dpc-2345	40	22	increases	increase	VERB
dpc-2345	40	23	treatment	treatment	NOUN
dpc-2345	40	24	duration	duration	NOUN
dpc-2345	40	25	,	,	PUNCT
dpc-2345	40	26	treatment	treatment	NOUN
dpc-2345	40	27	cost	cost	NOUN
dpc-2345	40	28	,	,	PUNCT
dpc-2345	40	29	side	side	NOUN
dpc-2345	40	30	effects	effect	NOUN
dpc-2345	40	31	like	like	ADP
dpc-2345	40	32	cardiac	cardiac	ADJ
dpc-2345	40	33	disturbances	disturbance	NOUN
dpc-2345	40	34	and	and	CCONJ
dpc-2345	40	35	hepatic	hepatic	NOUN
dpc-2345	40	36	toxicity	toxicity	NOUN
dpc-2345	40	37	,	,	PUNCT
dpc-2345	40	38	and	and	CCONJ
dpc-2345	40	39	drug	drug	NOUN
dpc-2345	40	40	interactions	interaction	NOUN
dpc-2345	40	41	.	.	PUNCT
dpc-2345	41	1	the	the	DET
dpc-2345	41	2	topical	topical	ADJ
dpc-2345	41	3	treatment	treatment	NOUN
dpc-2345	41	4	provides	provide	VERB
dpc-2345	41	5	an	an	DET
dpc-2345	41	6	alternative	alternative	ADJ
dpc-2345	41	7	approach	approach	NOUN
dpc-2345	41	8	to	to	PART
dpc-2345	41	9	evade	evade	VERB
dpc-2345	41	10	the	the	DET
dpc-2345	41	11	drawbacks	drawback	NOUN
dpc-2345	41	12	associated	associate	VERB
dpc-2345	41	13	with	with	ADP
dpc-2345	41	14	oral	oral	ADJ
dpc-2345	41	15	medicines	medicine	NOUN
dpc-2345	41	16	and	and	CCONJ
dpc-2345	41	17	improves	improve	VERB
dpc-2345	41	18	the	the	DET
dpc-2345	41	19	adherence	adherence	NOUN
dpc-2345	41	20	and	and	CCONJ
dpc-2345	41	21	localized	localized	ADJ
dpc-2345	41	22	effect	effect	NOUN
dpc-2345	41	23	[	[	X
dpc-2345	41	24	7	7	NUM
dpc-2345	41	25	-	-	SYM
dpc-2345	41	26	12	12	NUM
dpc-2345	41	27	]	]	PUNCT
dpc-2345	41	28	.	.	PUNCT
dpc-2345	42	1	the	the	DET
dpc-2345	42	2	topical	topical	ADJ
dpc-2345	42	3	treatments	treatment	NOUN
dpc-2345	42	4	approved	approve	VERB
dpc-2345	42	5	by	by	ADP
dpc-2345	42	6	the	the	DET
dpc-2345	42	7	fda	fda	PROPN
dpc-2345	42	8	for	for	ADP
dpc-2345	42	9	effective	effective	ADJ
dpc-2345	42	10	treatment	treatment	NOUN
dpc-2345	42	11	of	of	ADP
dpc-2345	42	12	onychomycosis	onychomycosis	NOUN
dpc-2345	42	13	include	include	VERB
dpc-2345	42	14	tavaborole	tavaborole	ADJ
dpc-2345	42	15	5	5	NUM
dpc-2345	42	16	%	%	NOUN
dpc-2345	42	17	solution	solution	NOUN
dpc-2345	42	18	,	,	PUNCT
dpc-2345	42	19	ciclopirox	ciclopirox	NOUN
dpc-2345	42	20	8	8	NUM
dpc-2345	42	21	%	%	NOUN
dpc-2345	42	22	nail	nail	NOUN
dpc-2345	42	23	lacquer	lacquer	NOUN
dpc-2345	42	24	,	,	PUNCT
dpc-2345	42	25	and	and	CCONJ
dpc-2345	42	26	efinaconazole	efinaconazole	NOUN
dpc-2345	42	27	10	10	NUM
dpc-2345	42	28	%	%	NOUN
dpc-2345	42	29	solution	solution	NOUN
dpc-2345	42	30	[	[	X
dpc-2345	42	31	13	13	NUM
dpc-2345	42	32	-	-	SYM
dpc-2345	42	33	14	14	NUM
dpc-2345	42	34	]	]	PUNCT
dpc-2345	42	35	.	.	PUNCT
dpc-2345	43	1	however	however	ADV
dpc-2345	43	2	,	,	PUNCT
dpc-2345	43	3	their	their	PRON
dpc-2345	43	4	effectiveness	effectiveness	NOUN
dpc-2345	43	5	is	be	AUX
dpc-2345	43	6	limited	limit	VERB
dpc-2345	43	7	due	due	ADP
dpc-2345	43	8	to	to	ADP
dpc-2345	43	9	the	the	DET
dpc-2345	43	10	minimal	minimal	ADJ
dpc-2345	43	11	permeability	permeability	NOUN
dpc-2345	43	12	of	of	ADP
dpc-2345	43	13	the	the	DET
dpc-2345	43	14	drug	drug	NOUN
dpc-2345	43	15	across	across	ADP
dpc-2345	43	16	the	the	DET
dpc-2345	43	17	nail	nail	NOUN
dpc-2345	43	18	plate	plate	NOUN
dpc-2345	43	19	.	.	PUNCT
dpc-2345	44	1	the	the	DET
dpc-2345	44	2	nail	nail	NOUN
dpc-2345	44	3	impermeability	impermeability	NOUN
dpc-2345	44	4	can	can	AUX
dpc-2345	44	5	be	be	AUX
dpc-2345	44	6	accredited	accredit	VERB
dpc-2345	44	7	to	to	ADP
dpc-2345	44	8	the	the	DET
dpc-2345	44	9	  	  	SPACE
dpc-2345	44	10	highly	highly	ADV
dpc-2345	44	11	stable	stable	ADJ
dpc-2345	44	12	hydrogen	hydrogen	NOUN
dpc-2345	44	13	bonds	bond	NOUN
dpc-2345	44	14	and	and	CCONJ
dpc-2345	44	15	disulfide	disulfide	NOUN
dpc-2345	44	16	linkages	linkage	NOUN
dpc-2345	44	17	in	in	ADP
dpc-2345	44	18	the	the	DET
dpc-2345	44	19	keratin	keratin	NOUN
dpc-2345	44	20	network	network	NOUN
dpc-2345	44	21	.	.	PUNCT
dpc-2345	45	1	moreover	moreover	ADV
dpc-2345	45	2	,	,	PUNCT
dpc-2345	45	3	globular	globular	ADJ
dpc-2345	45	4	proteins	protein	NOUN
dpc-2345	45	5	and	and	CCONJ
dpc-2345	45	6	keratin	keratin	NOUN
dpc-2345	45	7	fibres	fibre	NOUN
dpc-2345	45	8	make	make	VERB
dpc-2345	45	9	a	a	DET
dpc-2345	45	10	complex	complex	ADJ
dpc-2345	45	11	structure	structure	NOUN
dpc-2345	45	12	that	that	PRON
dpc-2345	45	13	makes	make	VERB
dpc-2345	45	14	the	the	DET
dpc-2345	45	15	nail	nail	NOUN
dpc-2345	45	16	plate	plate	NOUN
dpc-2345	45	17	the	the	DET
dpc-2345	45	18	most	most	ADV
dpc-2345	45	19	challenging	challenging	ADJ
dpc-2345	45	20	biological	biological	ADJ
dpc-2345	45	21	barrier	barrier	NOUN
dpc-2345	45	22	[	[	X
dpc-2345	45	23	3	3	NUM
dpc-2345	45	24	]	]	PUNCT
dpc-2345	45	25	.	.	PUNCT
dpc-2345	46	1	therefore	therefore	ADV
dpc-2345	46	2	,	,	PUNCT
dpc-2345	46	3	extensive	extensive	ADJ
dpc-2345	46	4	research	research	NOUN
dpc-2345	46	5	has	have	AUX
dpc-2345	46	6	been	be	AUX
dpc-2345	46	7	focused	focus	VERB
dpc-2345	46	8	on	on	ADP
dpc-2345	46	9	altering	alter	VERB
dpc-2345	46	10	the	the	DET
dpc-2345	46	11	nail	nail	NOUN
dpc-2345	46	12	plate	plate	NOUN
dpc-2345	46	13	barrier	barrier	NOUN
dpc-2345	46	14	by	by	ADP
dpc-2345	46	15	employing	employ	VERB
dpc-2345	46	16	various	various	ADJ
dpc-2345	46	17	approaches	approach	NOUN
dpc-2345	46	18	,	,	PUNCT
dpc-2345	46	19	which	which	PRON
dpc-2345	46	20	include	include	VERB
dpc-2345	46	21	physical	physical	ADJ
dpc-2345	46	22	methods	method	NOUN
dpc-2345	46	23	,	,	PUNCT
dpc-2345	46	24	mechanical	mechanical	ADJ
dpc-2345	46	25	methods	method	NOUN
dpc-2345	46	26	,	,	PUNCT
dpc-2345	46	27	chemical	chemical	NOUN
dpc-2345	46	28	treatments	treatment	NOUN
dpc-2345	46	29	,	,	PUNCT
dpc-2345	46	30	and	and	CCONJ
dpc-2345	46	31	penetration	penetration	NOUN
dpc-2345	46	32	enhancers	enhancer	NOUN
dpc-2345	46	33	;	;	PUNCT
dpc-2345	46	34	wherein	wherein	SCONJ
dpc-2345	46	35	one	one	NUM
dpc-2345	46	36	of	of	ADP
dpc-2345	46	37	the	the	DET
dpc-2345	46	38	most	most	ADV
dpc-2345	46	39	commonly	commonly	ADV
dpc-2345	46	40	used	use	VERB
dpc-2345	46	41	approaches	approach	NOUN
dpc-2345	46	42	is	be	AUX
dpc-2345	46	43	the	the	DET
dpc-2345	46	44	use	use	NOUN
dpc-2345	46	45	of	of	ADP
dpc-2345	46	46	penetration	penetration	NOUN
dpc-2345	46	47	enhancers	enhancer	NOUN
dpc-2345	46	48	,	,	PUNCT
dpc-2345	46	49	which	which	PRON
dpc-2345	46	50	act	act	VERB
dpc-2345	46	51	by	by	ADP
dpc-2345	46	52	disrupting	disrupt	VERB
dpc-2345	46	53	the	the	DET
dpc-2345	46	54	keratinized	keratinized	ADJ
dpc-2345	46	55	structure	structure	NOUN
dpc-2345	46	56	of	of	ADP
dpc-2345	46	57	nail	nail	NOUN
dpc-2345	46	58	plate	plate	NOUN
dpc-2345	46	59	thereby	thereby	ADV
dpc-2345	46	60	increasing	increase	VERB
dpc-2345	46	61	the	the	DET
dpc-2345	46	62	diffusion	diffusion	NOUN
dpc-2345	46	63	gradient	gradient	NOUN
dpc-2345	46	64	and	and	CCONJ
dpc-2345	46	65	penetration	penetration	NOUN
dpc-2345	46	66	capacity	capacity	NOUN
dpc-2345	46	67	of	of	ADP
dpc-2345	46	68	the	the	DET
dpc-2345	46	69	active	active	ADJ
dpc-2345	46	70	through	through	ADP
dpc-2345	46	71	the	the	DET
dpc-2345	46	72	nail	nail	NOUN
dpc-2345	46	73	plate	plate	NOUN
dpc-2345	47	1	[	[	X
dpc-2345	47	2	15	15	NUM
dpc-2345	47	3	-	-	SYM
dpc-2345	47	4	18	18	NUM
dpc-2345	47	5	]	]	PUNCT
dpc-2345	47	6	.	.	PUNCT
dpc-2345	48	1	researches	research	VERB
dpc-2345	48	2	from	from	ADP
dpc-2345	48	3	past	past	ADJ
dpc-2345	48	4	decades	decade	NOUN
dpc-2345	48	5	have	have	AUX
dpc-2345	48	6	shown	show	VERB
dpc-2345	48	7	that	that	SCONJ
dpc-2345	48	8	chemical	chemical	ADJ
dpc-2345	48	9	penetration	penetration	NOUN
dpc-2345	48	10	enhancers	enhancer	NOUN
dpc-2345	48	11	yield	yield	VERB
dpc-2345	48	12	higher	high	ADJ
dpc-2345	48	13	permeation	permeation	NOUN
dpc-2345	48	14	rates	rate	NOUN
dpc-2345	48	15	than	than	ADP
dpc-2345	48	16	other	other	ADJ
dpc-2345	48	17	approaches	approach	NOUN
dpc-2345	48	18	for	for	ADP
dpc-2345	48	19	effective	effective	ADJ
dpc-2345	48	20	transungual	transungual	ADJ
dpc-2345	48	21	delivery	delivery	NOUN
dpc-2345	48	22	,	,	PUNCT
dpc-2345	48	23	but	but	CCONJ
dpc-2345	48	24	irritancy	irritancy	NOUN
dpc-2345	48	25	at	at	ADP
dpc-2345	48	26	the	the	DET
dpc-2345	48	27	site	site	NOUN
dpc-2345	48	28	of	of	ADP
dpc-2345	48	29	application	application	NOUN
dpc-2345	48	30	always	always	ADV
dpc-2345	48	31	remains	remain	VERB
dpc-2345	48	32	a	a	DET
dpc-2345	48	33	challenge	challenge	NOUN
dpc-2345	48	34	[	[	X
dpc-2345	48	35	19,20	19,20	X
dpc-2345	48	36	]	]	X
dpc-2345	48	37	.	.	PUNCT
dpc-2345	49	1	therefore	therefore	ADV
dpc-2345	49	2	,	,	PUNCT
dpc-2345	49	3	research	research	NOUN
dpc-2345	49	4	has	have	AUX
dpc-2345	49	5	been	be	AUX
dpc-2345	49	6	oriented	orient	VERB
dpc-2345	49	7	towards	towards	ADP
dpc-2345	49	8	finding	find	VERB
dpc-2345	49	9	safe	safe	ADJ
dpc-2345	49	10	and	and	CCONJ
dpc-2345	49	11	effective	effective	ADJ
dpc-2345	49	12	penetration	penetration	NOUN
dpc-2345	49	13	enhancers	enhancer	NOUN
dpc-2345	49	14	from	from	ADP
dpc-2345	49	15	natural	natural	ADJ
dpc-2345	49	16	sources	source	NOUN
dpc-2345	49	17	.	.	PUNCT
dpc-2345	50	1	terpenes	terpene	NOUN
dpc-2345	50	2	acquired	acquire	VERB
dpc-2345	50	3	from	from	ADP
dpc-2345	50	4	natural	natural	ADJ
dpc-2345	50	5	sources	source	NOUN
dpc-2345	50	6	have	have	AUX
dpc-2345	50	7	emerged	emerge	VERB
dpc-2345	50	8	as	as	ADP
dpc-2345	50	9	promising	promise	VERB
dpc-2345	50	10	candidates	candidate	NOUN
dpc-2345	50	11	and	and	CCONJ
dpc-2345	50	12	are	be	AUX
dpc-2345	50	13	considered	consider	VERB
dpc-2345	50	14	as	as	ADV
dpc-2345	50	15	clinically	clinically	ADV
dpc-2345	50	16	acceptable	acceptable	ADJ
dpc-2345	50	17	penetration	penetration	NOUN
dpc-2345	50	18	enhancers	enhancer	NOUN
dpc-2345	50	19	.	.	PUNCT
dpc-2345	51	1	in	in	ADP
dpc-2345	51	2	addition	addition	NOUN
dpc-2345	51	3	,	,	PUNCT
dpc-2345	51	4	many	many	ADJ
dpc-2345	51	5	terpenes	terpene	NOUN
dpc-2345	51	6	appear	appear	VERB
dpc-2345	51	7	in	in	ADP
dpc-2345	51	8	the	the	DET
dpc-2345	51	9	list	list	NOUN
dpc-2345	51	10	of	of	ADP
dpc-2345	51	11	generally	generally	ADV
dpc-2345	51	12	recognized	recognize	VERB
dpc-2345	51	13	as	as	ADP
dpc-2345	51	14	safe	safe	ADJ
dpc-2345	51	15	(	(	PUNCT
dpc-2345	51	16	gras	gras	PROPN
dpc-2345	51	17	)	)	PUNCT
dpc-2345	51	18	agents	agent	NOUN
dpc-2345	51	19	published	publish	VERB
dpc-2345	51	20	by	by	ADP
dpc-2345	51	21	the	the	DET
dpc-2345	51	22	usfda	usfda	NOUN
dpc-2345	51	23	.	.	PUNCT
dpc-2345	52	1	terpenes	terpene	NOUN
dpc-2345	52	2	are	be	AUX
dpc-2345	52	3	used	use	VERB
dpc-2345	52	4	for	for	ADP
dpc-2345	52	5	permeation	permeation	NOUN
dpc-2345	52	6	enhancements	enhancement	NOUN
dpc-2345	52	7	of	of	ADP
dpc-2345	52	8	both	both	CCONJ
dpc-2345	52	9	lipophilic	lipophilic	ADJ
dpc-2345	52	10	and	and	CCONJ
dpc-2345	52	11	hydrophilic	hydrophilic	ADJ
dpc-2345	52	12	drugs	drug	NOUN
dpc-2345	52	13	.	.	PUNCT
dpc-2345	53	1	their	their	PRON
dpc-2345	53	2	activity	activity	NOUN
dpc-2345	53	3	depends	depend	VERB
dpc-2345	53	4	on	on	ADP
dpc-2345	53	5	their	their	PRON
dpc-2345	53	6	chemical	chemical	NOUN
dpc-2345	53	7	structure	structure	NOUN
dpc-2345	53	8	and	and	CCONJ
dpc-2345	53	9	physicochemical	physicochemical	ADJ
dpc-2345	53	10	properties	property	NOUN
dpc-2345	53	11	such	such	ADJ
dpc-2345	53	12	as	as	ADP
dpc-2345	53	13	degree	degree	NOUN
dpc-2345	53	14	of	of	ADP
dpc-2345	53	15	unsaturation	unsaturation	NOUN
dpc-2345	53	16	,	,	PUNCT
dpc-2345	53	17	boiling	boiling	NOUN
dpc-2345	53	18	point	point	NOUN
dpc-2345	53	19	,	,	PUNCT
dpc-2345	53	20	size	size	NOUN
dpc-2345	53	21	and	and	CCONJ
dpc-2345	53	22	chirality	chirality	NOUN
dpc-2345	53	23	,	,	PUNCT
dpc-2345	53	24	the	the	DET
dpc-2345	53	25	energy	energy	NOUN
dpc-2345	53	26	of	of	ADP
dpc-2345	53	27	vaporization	vaporization	NOUN
dpc-2345	53	28	,	,	PUNCT
dpc-2345	53	29	and	and	CCONJ
dpc-2345	53	30	lipophilicity	lipophilicity	NOUN
dpc-2345	53	31	[	[	X
dpc-2345	53	32	21	21	NUM
dpc-2345	53	33	]	]	PUNCT
dpc-2345	53	34	.	.	PUNCT
dpc-2345	54	1	in	in	ADP
dpc-2345	54	2	the	the	DET
dpc-2345	54	3	present	present	ADJ
dpc-2345	54	4	study	study	NOUN
dpc-2345	54	5	,	,	PUNCT
dpc-2345	54	6	we	we	PRON
dpc-2345	54	7	chose	choose	VERB
dpc-2345	54	8	terbinafine	terbinafine	NOUN
dpc-2345	54	9	,	,	PUNCT
dpc-2345	54	10	an	an	DET
dpc-2345	54	11	allylamine	allylamine	ADJ
dpc-2345	54	12	fungicidal	fungicidal	ADJ
dpc-2345	54	13	drug	drug	NOUN
dpc-2345	54	14	that	that	PRON
dpc-2345	54	15	acts	act	VERB
dpc-2345	54	16	by	by	ADP
dpc-2345	54	17	inhibiting	inhibit	VERB
dpc-2345	54	18	squalene	squalene	NOUN
dpc-2345	54	19	epoxidase	epoxidase	NOUN
dpc-2345	54	20	in	in	ADP
dpc-2345	54	21	the	the	DET
dpc-2345	54	22	ergosterol	ergosterol	NOUN
dpc-2345	54	23	biosynthesis	biosynthesis	NOUN
dpc-2345	54	24	pathway	pathway	NOUN
dpc-2345	54	25	and	and	CCONJ
dpc-2345	54	26	shows	show	VERB
dpc-2345	54	27	higher	high	ADJ
dpc-2345	54	28	efficacy	efficacy	NOUN
dpc-2345	54	29	against	against	ADP
dpc-2345	54	30	dermatophytes	dermatophyte	NOUN
dpc-2345	54	31	and	and	CCONJ
dpc-2345	54	32	many	many	ADJ
dpc-2345	54	33	non	non	NOUN
dpc-2345	54	34	-	-	NOUN
dpc-2345	54	35	dermatophytes	dermatophyte	NOUN
dpc-2345	54	36	[	[	X
dpc-2345	54	37	22	22	NUM
dpc-2345	54	38	]	]	PUNCT
dpc-2345	54	39	.	.	PUNCT
dpc-2345	55	1	topical	topical	ADJ
dpc-2345	55	2	therapy	therapy	NOUN
dpc-2345	55	3	can	can	AUX
dpc-2345	55	4	eminently	eminently	ADV
dpc-2345	55	5	treat	treat	VERB
dpc-2345	55	6	onychomycosis	onychomycosis	NOUN
dpc-2345	55	7	.	.	PUNCT
dpc-2345	56	1	the	the	DET
dpc-2345	56	2	route	route	NOUN
dpc-2345	56	3	is	be	AUX
dpc-2345	56	4	highly	highly	ADV
dpc-2345	56	5	advantageous	advantageous	ADJ
dpc-2345	56	6	attributable	attributable	ADJ
dpc-2345	56	7	to	to	ADP
dpc-2345	56	8	its	its	PRON
dpc-2345	56	9	localised	localised	ADJ
dpc-2345	56	10	effect	effect	NOUN
dpc-2345	56	11	and	and	CCONJ
dpc-2345	56	12	minimal	minimal	ADJ
dpc-2345	56	13	adverse	adverse	ADJ
dpc-2345	56	14	effect	effect	NOUN
dpc-2345	56	15	profile	profile	NOUN
dpc-2345	56	16	.	.	PUNCT
dpc-2345	57	1	however	however	ADV
dpc-2345	57	2	,	,	PUNCT
dpc-2345	57	3	its	its	PRON
dpc-2345	57	4	potential	potential	NOUN
dpc-2345	57	5	is	be	AUX
dpc-2345	57	6	hampered	hamper	VERB
dpc-2345	57	7	by	by	ADP
dpc-2345	57	8	the	the	DET
dpc-2345	57	9	rigid	rigid	ADJ
dpc-2345	57	10	keratinous	keratinous	ADJ
dpc-2345	57	11	structure	structure	NOUN
dpc-2345	57	12	of	of	ADP
dpc-2345	57	13	the	the	DET
dpc-2345	57	14	nail	nail	NOUN
dpc-2345	57	15	plate	plate	NOUN
dpc-2345	57	16	which	which	PRON
dpc-2345	57	17	is	be	AUX
dpc-2345	57	18	hard	hard	ADJ
dpc-2345	57	19	to	to	PART
dpc-2345	57	20	breach	breach	VERB
dpc-2345	57	21	[	[	PRON
dpc-2345	57	22	23	23	NUM
dpc-2345	57	23	]	]	PUNCT
dpc-2345	57	24	.	.	PUNCT
dpc-2345	58	1	objectives	objective	NOUN
dpc-2345	58	2	therefore	therefore	ADV
dpc-2345	58	3	,	,	PUNCT
dpc-2345	58	4	our	our	PRON
dpc-2345	58	5	research	research	NOUN
dpc-2345	58	6	has	have	AUX
dpc-2345	58	7	been	be	AUX
dpc-2345	58	8	centered	center	VERB
dpc-2345	58	9	on	on	ADP
dpc-2345	58	10	improvement	improvement	NOUN
dpc-2345	58	11	of	of	ADP
dpc-2345	58	12	transungual	transungual	ADJ
dpc-2345	58	13	delivery	delivery	NOUN
dpc-2345	58	14	of	of	ADP
dpc-2345	58	15	terbinafine	terbinafine	NOUN
dpc-2345	58	16	with	with	ADP
dpc-2345	58	17	the	the	DET
dpc-2345	58	18	assistance	assistance	NOUN
dpc-2345	58	19	of	of	ADP
dpc-2345	58	20	natural	natural	ADJ
dpc-2345	58	21	permeation	permeation	NOUN
dpc-2345	58	22	enhancers	enhancer	NOUN
dpc-2345	58	23	ie	ie	PRON
dpc-2345	58	24	terpenes	terpene	NOUN
dpc-2345	58	25	viz	viz	PROPN
dpc-2345	58	26	.	.	PUNCT
dpc-2345	59	1	lavandulol	lavandulol	PROPN
dpc-2345	59	2	,	,	PUNCT
dpc-2345	59	3	safranal	safranal	ADJ
dpc-2345	59	4	,	,	PUNCT
dpc-2345	59	5	rose	rise	VERB
dpc-2345	59	6	oxide	oxide	NOUN
dpc-2345	59	7	,	,	PUNCT
dpc-2345	59	8	limonene	limonene	NOUN
dpc-2345	59	9	,	,	PUNCT
dpc-2345	59	10	3	3	NUM
dpc-2345	59	11	-	-	PUNCT
dpc-2345	59	12	methyl-2	methyl-2	NOUN
dpc-2345	59	13	-	-	PUNCT
dpc-2345	59	14	butene-1	butene-1	NOUN
dpc-2345	59	15	-	-	PUNCT
dpc-2345	59	16	ol	ol	NOUN
dpc-2345	59	17	,	,	PUNCT
dpc-2345	59	18	and	and	CCONJ
dpc-2345	59	19	linalool	linalool	NOUN
dpc-2345	59	20	.	.	PUNCT
dpc-2345	60	1	the	the	DET
dpc-2345	60	2	salient	salient	NOUN
dpc-2345	60	3	features	feature	NOUN
dpc-2345	60	4	of	of	ADP
dpc-2345	60	5	the	the	DET
dpc-2345	60	6	studied	study	VERB
dpc-2345	60	7	terpenes	terpene	NOUN
dpc-2345	60	8	have	have	AUX
dpc-2345	60	9	been	be	AUX
dpc-2345	60	10	highlighted	highlight	VERB
dpc-2345	60	11	in	in	ADP
dpc-2345	60	12	table	table	NOUN
dpc-2345	60	13	1	1	NUM
dpc-2345	60	14	.	.	PUNCT
dpc-2345	61	1	methods	method	NOUN
dpc-2345	61	2	terbinafine	terbinafine	NOUN
dpc-2345	61	3	was	be	AUX
dpc-2345	61	4	purchased	purchase	VERB
dpc-2345	61	5	from	from	ADP
dpc-2345	61	6	virupaksha	virupaksha	ADJ
dpc-2345	61	7	organics	organic	NOUN
dpc-2345	61	8	limited	limit	VERB
dpc-2345	61	9	.	.	PUNCT
dpc-2345	62	1	lavandulol	lavandulol	PROPN
dpc-2345	62	2	,	,	PUNCT
dpc-2345	62	3	safranal	safranal	ADJ
dpc-2345	62	4	,	,	PUNCT
dpc-2345	62	5	rose	rise	VERB
dpc-2345	62	6	oxide	oxide	NOUN
dpc-2345	62	7	,	,	PUNCT
dpc-2345	62	8	limonene	limonene	NOUN
dpc-2345	62	9	,	,	PUNCT
dpc-2345	62	10	3	3	NUM
dpc-2345	62	11	-	-	PUNCT
dpc-2345	62	12	methyl-2	methyl-2	NOUN
dpc-2345	62	13	-	-	PUNCT
dpc-2345	62	14	butene-1	butene-1	NOUN
dpc-2345	62	15	-	-	PUNCT
dpc-2345	62	16	ol	ol	NOUN
dpc-2345	62	17	,	,	PUNCT
dpc-2345	62	18	and	and	CCONJ
dpc-2345	62	19	linalool	linalool	NOUN
dpc-2345	62	20	were	be	AUX
dpc-2345	62	21	purchased	purchase	VERB
dpc-2345	62	22	from	from	ADP
dpc-2345	62	23	sigma	sigma	PROPN
dpc-2345	62	24	-	-	PUNCT
dpc-2345	62	25	aldrich	aldrich	NOUN
dpc-2345	62	26	.	.	PUNCT
dpc-2345	63	1	absolute	absolute	ADJ
dpc-2345	63	2	ethanol	ethanol	NOUN
dpc-2345	63	3	,	,	PUNCT
dpc-2345	63	4	methanol	methanol	NOUN
dpc-2345	63	5	,	,	PUNCT
dpc-2345	63	6	hydrochloric	hydrochloric	ADJ
dpc-2345	63	7	acid	acid	NOUN
dpc-2345	63	8	,	,	PUNCT
dpc-2345	63	9	sodium	sodium	NOUN
dpc-2345	63	10	hydroxide	hydroxide	NOUN
dpc-2345	63	11	,	,	PUNCT
dpc-2345	63	12	propylene	propylene	NOUN
dpc-2345	63	13	glycol	glycol	NOUN
dpc-2345	63	14	,	,	PUNCT
dpc-2345	63	15	tween	tween	NOUN
dpc-2345	63	16	80	80	NUM
dpc-2345	63	17	,	,	PUNCT
dpc-2345	63	18	and	and	CCONJ
dpc-2345	63	19	hplc	hplc	NOUN
dpc-2345	63	20	grade	grade	NOUN
dpc-2345	63	21	methanol	methanol	NOUN
dpc-2345	63	22	were	be	AUX
dpc-2345	63	23	purchased	purchase	VERB
dpc-2345	63	24	from	from	ADP
dpc-2345	63	25	s.d	s.d	PROPN
dpc-2345	63	26	.	.	PROPN
dpc-2345	63	27	fine	fine	ADJ
dpc-2345	63	28	chemicals	chemical	NOUN
dpc-2345	63	29	.	.	PUNCT
dpc-2345	64	1	all	all	DET
dpc-2345	64	2	chemicals	chemical	NOUN
dpc-2345	64	3	were	be	AUX
dpc-2345	64	4	of	of	ADP
dpc-2345	64	5	analytical	analytical	ADJ
dpc-2345	64	6	reagent	reagent	ADJ
dpc-2345	64	7	grade	grade	NOUN
dpc-2345	64	8	.	.	PUNCT
dpc-2345	65	1	liquid	liquid	ADJ
dpc-2345	65	2	chromatographic	chromatographic	ADJ
dpc-2345	65	3	conditions	condition	NOUN
dpc-2345	65	4	hplc	hplc	NOUN
dpc-2345	65	5	quaternary	quaternary	ADJ
dpc-2345	65	6	system	system	NOUN
dpc-2345	65	7	consisting	consist	VERB
dpc-2345	65	8	of	of	ADP
dpc-2345	65	9	lichrospher	lichrospher	NOUN
dpc-2345	65	10	c18	c18	NOUN
dpc-2345	65	11	reverse	reverse	NOUN
dpc-2345	65	12	-	-	PUNCT
dpc-2345	65	13	phase	phase	NOUN
dpc-2345	65	14	column	column	NOUN
dpc-2345	65	15	of	of	ADP
dpc-2345	65	16	25	25	NUM
dpc-2345	65	17	x	x	SYM
dpc-2345	65	18	4.6	4.6	NUM
dpc-2345	65	19	mm	mm	NOUN
dpc-2345	65	20	with	with	ADP
dpc-2345	65	21	particle	particle	NOUN
dpc-2345	65	22	size	size	NOUN
dpc-2345	65	23	of	of	ADP
dpc-2345	65	24	5	5	NUM
dpc-2345	65	25	μm	μm	NOUN
dpc-2345	65	26	was	be	AUX
dpc-2345	65	27	used	use	VERB
dpc-2345	65	28	for	for	ADP
dpc-2345	65	29	performing	perform	VERB
dpc-2345	65	30	hplc	hplc	NOUN
dpc-2345	65	31	analysis	analysis	NOUN
dpc-2345	65	32	.	.	PUNCT
dpc-2345	66	1	all	all	DET
dpc-2345	66	2	analyses	analysis	NOUN
dpc-2345	66	3	were	be	AUX
dpc-2345	66	4	carried	carry	VERB
dpc-2345	66	5	out	out	ADP
dpc-2345	66	6	under	under	ADP
dpc-2345	66	7	isocratic	isocratic	ADJ
dpc-2345	66	8	conditions	condition	NOUN
dpc-2345	66	9	at	at	ADP
dpc-2345	66	10	a	a	DET
dpc-2345	66	11	flow	flow	NOUN
dpc-2345	66	12	review	review	NOUN
dpc-2345	66	13	|	|	ADV
dpc-2345	66	14	dermatol	dermatol	ADJ
dpc-2345	66	15	pract	pract	NOUN
dpc-2345	66	16	concept	concept	NOUN
dpc-2345	66	17	.	.	PUNCT
dpc-2345	67	1	2022;12(4):e2022202	2022;12(4):e2022202	NUM
dpc-2345	67	2	3	3	NUM
dpc-2345	67	3	rate	rate	NOUN
dpc-2345	67	4	of	of	ADP
dpc-2345	67	5	1ml	1ml	ADJ
dpc-2345	67	6	/	/	SYM
dpc-2345	67	7	min	min	NOUN
dpc-2345	67	8	using	use	VERB
dpc-2345	67	9	mobile	mobile	ADJ
dpc-2345	67	10	phase	phase	NOUN
dpc-2345	67	11	methanol	methanol	NOUN
dpc-2345	67	12	:	:	PUNCT
dpc-2345	67	13	acetonitrile	acetonitrile	NOUN
dpc-2345	67	14	:	:	PUNCT
dpc-2345	67	15	0.2	0.2	NUM
dpc-2345	67	16	%	%	NOUN
dpc-2345	67	17	triethylamine	triethylamine	NOUN
dpc-2345	67	18	(	(	PUNCT
dpc-2345	67	19	55:35:10	55:35:10	NUM
dpc-2345	67	20	,	,	PUNCT
dpc-2345	67	21	%	%	NOUN
dpc-2345	67	22	v	v	NOUN
dpc-2345	67	23	/	/	SYM
dpc-2345	67	24	v	v	NOUN
dpc-2345	67	25	)	)	PUNCT
dpc-2345	67	26	with	with	ADP
dpc-2345	67	27	u.v	u.v	PROPN
dpc-2345	67	28	.	.	PROPN
dpc-2345	67	29	detection	detection	NOUN
dpc-2345	67	30	at	at	ADP
dpc-2345	67	31	280	280	NUM
dpc-2345	67	32	 	 	SPACE
dpc-2345	67	33	nm	nm	NOUN
dpc-2345	67	34	[	[	X
dpc-2345	67	35	24	24	NUM
dpc-2345	67	36	]	]	PUNCT
dpc-2345	67	37	.	.	PUNCT
dpc-2345	68	1	preparation	preparation	NOUN
dpc-2345	68	2	of	of	ADP
dpc-2345	68	3	stock	stock	NOUN
dpc-2345	68	4	and	and	CCONJ
dpc-2345	68	5	working	working	NOUN
dpc-2345	68	6	solutions	solution	NOUN
dpc-2345	68	7	in	in	ADP
dpc-2345	68	8	propylene	propylene	NOUN
dpc-2345	68	9	glycol	glycol	NOUN
dpc-2345	68	10	:	:	PUNCT
dpc-2345	68	11	tween	tween	NOUN
dpc-2345	68	12	80	80	NUM
dpc-2345	68	13	:	:	PUNCT
dpc-2345	68	14	ethanol	ethanol	NOUN
dpc-2345	68	15	:	:	PUNCT
dpc-2345	68	16	dimethyl	dimethyl	NOUN
dpc-2345	68	17	sulfoxide	sulfoxide	NOUN
dpc-2345	68	18	(	(	PUNCT
dpc-2345	68	19	30	30	NUM
dpc-2345	68	20	:	:	SYM
dpc-2345	68	21	3	3	NUM
dpc-2345	68	22	:	:	PUNCT
dpc-2345	68	23	62	62	NUM
dpc-2345	68	24	:	:	SYM
dpc-2345	68	25	5	5	NUM
dpc-2345	68	26	)	)	PUNCT
dpc-2345	68	27	,	,	PUNCT
dpc-2345	68	28	the	the	DET
dpc-2345	68	29	stock	stock	NOUN
dpc-2345	68	30	solution	solution	NOUN
dpc-2345	68	31	of	of	ADP
dpc-2345	68	32	terbinafine	terbinafine	NOUN
dpc-2345	68	33	(	(	PUNCT
dpc-2345	68	34	25	25	NUM
dpc-2345	68	35	mg	mg	NUM
dpc-2345	68	36	/	/	SYM
dpc-2345	68	37	ml	ml	NOUN
dpc-2345	68	38	)	)	PUNCT
dpc-2345	68	39	was	be	AUX
dpc-2345	68	40	prepared	prepare	VERB
dpc-2345	68	41	and	and	CCONJ
dpc-2345	68	42	stored	store	VERB
dpc-2345	68	43	at	at	ADP
dpc-2345	68	44	-20	-20	NUM
dpc-2345	68	45	°	°	NOUN
dpc-2345	68	46	c	c	NOUN
dpc-2345	68	47	.	.	PUNCT
dpc-2345	69	1	by	by	ADP
dpc-2345	69	2	diluting	dilute	VERB
dpc-2345	69	3	the	the	DET
dpc-2345	69	4	stock	stock	NOUN
dpc-2345	69	5	solution	solution	NOUN
dpc-2345	69	6	in	in	ADP
dpc-2345	69	7	water	water	NOUN
dpc-2345	69	8	:	:	PUNCT
dpc-2345	69	9	ethanol	ethanol	NOUN
dpc-2345	69	10	(	(	PUNCT
dpc-2345	69	11	50:50	50:50	NUM
dpc-2345	69	12	,	,	PUNCT
dpc-2345	69	13	v	v	NOUN
dpc-2345	69	14	/	/	SYM
dpc-2345	69	15	v	v	NOUN
dpc-2345	69	16	)	)	PUNCT
dpc-2345	69	17	five	five	NUM
dpc-2345	69	18	times	time	NOUN
dpc-2345	69	19	,	,	PUNCT
dpc-2345	69	20	terpene	terpene	NOUN
dpc-2345	69	21	-	-	PUNCT
dpc-2345	69	22	free	free	ADJ
dpc-2345	69	23	working	working	NOUN
dpc-2345	69	24	solution	solution	NOUN
dpc-2345	69	25	(	(	PUNCT
dpc-2345	69	26	control	control	NOUN
dpc-2345	69	27	)	)	PUNCT
dpc-2345	69	28	was	be	AUX
dpc-2345	69	29	prepared	prepare	VERB
dpc-2345	69	30	.	.	PUNCT
dpc-2345	70	1	the	the	DET
dpc-2345	70	2	concentration	concentration	NOUN
dpc-2345	70	3	was	be	AUX
dpc-2345	70	4	selected	select	VERB
dpc-2345	70	5	based	base	VERB
dpc-2345	70	6	on	on	ADP
dpc-2345	70	7	the	the	DET
dpc-2345	70	8	method	method	NOUN
dpc-2345	70	9	sensitivity	sensitivity	NOUN
dpc-2345	70	10	used	use	VERB
dpc-2345	70	11	in	in	ADP
dpc-2345	70	12	the	the	DET
dpc-2345	70	13	experiment	experiment	NOUN
dpc-2345	70	14	and	and	CCONJ
dpc-2345	70	15	the	the	DET
dpc-2345	70	16	terbinafine	terbinafine	NOUN
dpc-2345	70	17	solubility	solubility	NOUN
dpc-2345	70	18	.	.	PUNCT
dpc-2345	71	1	further	far	ADV
dpc-2345	71	2	,	,	PUNCT
dpc-2345	71	3	6	6	NUM
dpc-2345	71	4	working	working	NOUN
dpc-2345	71	5	solutions	solution	NOUN
dpc-2345	71	6	were	be	AUX
dpc-2345	71	7	prepared	prepare	VERB
dpc-2345	71	8	,	,	PUNCT
dpc-2345	71	9	each	each	PRON
dpc-2345	71	10	containing	contain	VERB
dpc-2345	71	11	5	5	NUM
dpc-2345	71	12	mg	mg	NUM
dpc-2345	71	13	/	/	SYM
dpc-2345	71	14	ml	ml	PROPN
dpc-2345	71	15	of	of	ADP
dpc-2345	71	16	terbinafine	terbinafine	ADJ
dpc-2345	71	17	stock	stock	NOUN
dpc-2345	71	18	solution	solution	NOUN
dpc-2345	71	19	and	and	CCONJ
dpc-2345	71	20	6	6	NUM
dpc-2345	71	21	%	%	NOUN
dpc-2345	71	22	of	of	ADP
dpc-2345	71	23	terpenes	terpene	NOUN
dpc-2345	71	24	(	(	PUNCT
dpc-2345	71	25	solution	solution	NOUN
dpc-2345	71	26	b	b	PROPN
dpc-2345	71	27	,	,	PUNCT
dpc-2345	71	28	c	c	NOUN
dpc-2345	71	29	,	,	PUNCT
dpc-2345	71	30	d	d	NOUN
dpc-2345	71	31	,	,	PUNCT
dpc-2345	71	32	e	e	NOUN
dpc-2345	71	33	,	,	PUNCT
dpc-2345	71	34	f	f	X
dpc-2345	71	35	,	,	PUNCT
dpc-2345	71	36	and	and	CCONJ
dpc-2345	71	37	g	g	PROPN
dpc-2345	71	38	labelled	label	VERB
dpc-2345	71	39	for	for	ADP
dpc-2345	71	40	lavandulol	lavandulol	ADJ
dpc-2345	71	41	,	,	PUNCT
dpc-2345	71	42	safranal	safranal	ADJ
dpc-2345	71	43	,	,	PUNCT
dpc-2345	71	44	rose	rise	VERB
dpc-2345	71	45	oxide	oxide	NOUN
dpc-2345	71	46	,	,	PUNCT
dpc-2345	71	47	limonene	limonene	NOUN
dpc-2345	71	48	,	,	PUNCT
dpc-2345	71	49	3	3	NUM
dpc-2345	71	50	-	-	PUNCT
dpc-2345	71	51	methyl-2	methyl-2	NOUN
dpc-2345	71	52	-	-	PUNCT
dpc-2345	71	53	butene-1	butene-1	NOUN
dpc-2345	71	54	-	-	PUNCT
dpc-2345	71	55	ol	ol	NOUN
dpc-2345	71	56	,	,	PUNCT
dpc-2345	71	57	and	and	CCONJ
dpc-2345	71	58	linalool	linalool	NOUN
dpc-2345	71	59	respectively	respectively	ADV
dpc-2345	71	60	)	)	PUNCT
dpc-2345	71	61	.	.	PUNCT
dpc-2345	72	1	to	to	PART
dpc-2345	72	2	assess	assess	VERB
dpc-2345	72	3	the	the	DET
dpc-2345	72	4	optimal	optimal	ADJ
dpc-2345	72	5	effect	effect	NOUN
dpc-2345	72	6	of	of	ADP
dpc-2345	72	7	terpenes	terpene	NOUN
dpc-2345	72	8	on	on	ADP
dpc-2345	72	9	transungual	transungual	ADJ
dpc-2345	72	10	delivery	delivery	NOUN
dpc-2345	72	11	of	of	ADP
dpc-2345	72	12	terbinafine	terbinafine	NOUN
dpc-2345	72	13	,	,	PUNCT
dpc-2345	72	14	terpenes	terpene	NOUN
dpc-2345	72	15	concentration	concentration	NOUN
dpc-2345	72	16	was	be	AUX
dpc-2345	72	17	chosen	choose	VERB
dpc-2345	72	18	to	to	PART
dpc-2345	72	19	be	be	AUX
dpc-2345	72	20	more	more	ADJ
dpc-2345	72	21	than	than	ADP
dpc-2345	72	22	4.7	4.7	NUM
dpc-2345	72	23	%	%	NOUN
dpc-2345	72	24	,	,	PUNCT
dpc-2345	72	25	which	which	PRON
dpc-2345	72	26	emulated	emulate	VERB
dpc-2345	72	27	the	the	DET
dpc-2345	72	28	highest	high	ADJ
dpc-2345	72	29	concentration	concentration	NOUN
dpc-2345	72	30	of	of	ADP
dpc-2345	72	31	terpene	terpene	NOUN
dpc-2345	72	32	in	in	ADP
dpc-2345	72	33	market	market	NOUN
dpc-2345	72	34	formulation	formulation	NOUN
dpc-2345	72	35	viz	viz	PROPN
dpc-2345	72	36	.	.	PUNCT
dpc-2345	73	1	vicks	vick	NOUN
dpc-2345	73	2	vaporub	vaporub	PROPN
dpc-2345	73	3	®	®	PROPN
dpc-2345	73	4	(	(	PUNCT
dpc-2345	73	5	camphor	camphor	NOUN
dpc-2345	73	6	,	,	PUNCT
dpc-2345	73	7	4.7	4.7	NUM
dpc-2345	73	8	%	%	NOUN
dpc-2345	73	9	)	)	PUNCT
dpc-2345	73	10	.	.	PUNCT
dpc-2345	74	1	the	the	DET
dpc-2345	74	2	prepared	prepare	VERB
dpc-2345	74	3	solutions	solution	NOUN
dpc-2345	74	4	were	be	AUX
dpc-2345	74	5	subjected	subject	VERB
dpc-2345	74	6	to	to	ADP
dpc-2345	74	7	nail	nail	NOUN
dpc-2345	74	8	penetration	penetration	NOUN
dpc-2345	74	9	studies	study	NOUN
dpc-2345	74	10	[	[	X
dpc-2345	74	11	25	25	NUM
dpc-2345	74	12	]	]	PUNCT
dpc-2345	74	13	.	.	PUNCT
dpc-2345	75	1	ex	ex	ADJ
dpc-2345	75	2	-	-	ADJ
dpc-2345	75	3	vivo	vivo	ADJ
dpc-2345	75	4	nail	nail	NOUN
dpc-2345	75	5	penetration	penetration	NOUN
dpc-2345	75	6	studies	study	NOUN
dpc-2345	75	7	healthy	healthy	ADJ
dpc-2345	75	8	adult	adult	NOUN
dpc-2345	75	9	volunteers	volunteer	NOUN
dpc-2345	75	10	(	(	PUNCT
dpc-2345	75	11	5	5	NUM
dpc-2345	75	12	women	woman	NOUN
dpc-2345	75	13	,	,	PUNCT
dpc-2345	75	14	5	5	NUM
dpc-2345	75	15	men	man	NOUN
dpc-2345	75	16	,	,	PUNCT
dpc-2345	75	17	18	18	NUM
dpc-2345	75	18	-	-	SYM
dpc-2345	75	19	50	50	NUM
dpc-2345	75	20	-	-	PUNCT
dpc-2345	75	21	years	year	NOUN
dpc-2345	75	22	-	-	PUNCT
dpc-2345	75	23	old	old	ADJ
dpc-2345	75	24	,	,	PUNCT
dpc-2345	75	25	n	n	NOUN
dpc-2345	75	26	=	=	SYM
dpc-2345	75	27	10	10	NUM
dpc-2345	75	28	)	)	PUNCT
dpc-2345	75	29	who	who	PRON
dpc-2345	75	30	were	be	AUX
dpc-2345	75	31	not	not	PART
dpc-2345	75	32	on	on	ADP
dpc-2345	75	33	any	any	DET
dpc-2345	75	34	prescribed	prescribed	ADJ
dpc-2345	75	35	drug	drug	NOUN
dpc-2345	75	36	were	be	AUX
dpc-2345	75	37	chosen	choose	VERB
dpc-2345	75	38	for	for	ADP
dpc-2345	75	39	sample	sample	NOUN
dpc-2345	75	40	collection	collection	NOUN
dpc-2345	75	41	.	.	PUNCT
dpc-2345	76	1	nail	nail	NOUN
dpc-2345	76	2	samples	sample	NOUN
dpc-2345	76	3	were	be	AUX
dpc-2345	76	4	collected	collect	VERB
dpc-2345	76	5	using	use	VERB
dpc-2345	76	6	nail	nail	NOUN
dpc-2345	76	7	clippers	clipper	NOUN
dpc-2345	76	8	and	and	CCONJ
dpc-2345	76	9	scissors	scissor	NOUN
dpc-2345	76	10	.	.	PUNCT
dpc-2345	77	1	after	after	ADP
dpc-2345	77	2	giving	give	VERB
dpc-2345	77	3	a	a	DET
dpc-2345	77	4	brief	brief	ADJ
dpc-2345	77	5	description	description	NOUN
dpc-2345	77	6	about	about	ADP
dpc-2345	77	7	the	the	DET
dpc-2345	77	8	experiment	experiment	NOUN
dpc-2345	77	9	,	,	PUNCT
dpc-2345	77	10	written	write	VERB
dpc-2345	77	11	consent	consent	NOUN
dpc-2345	77	12	was	be	AUX
dpc-2345	77	13	taken	take	VERB
dpc-2345	77	14	from	from	ADP
dpc-2345	77	15	all	all	DET
dpc-2345	77	16	participating	participate	VERB
dpc-2345	77	17	individuals	individual	NOUN
dpc-2345	77	18	.	.	PUNCT
dpc-2345	78	1	no	no	DET
dpc-2345	78	2	ethical	ethical	ADJ
dpc-2345	78	3	approval	approval	NOUN
dpc-2345	78	4	was	be	AUX
dpc-2345	78	5	needed	need	VERB
dpc-2345	78	6	since	since	SCONJ
dpc-2345	78	7	nails	nail	NOUN
dpc-2345	78	8	are	be	AUX
dpc-2345	78	9	waste	waste	NOUN
dpc-2345	78	10	materials	material	NOUN
dpc-2345	78	11	and	and	CCONJ
dpc-2345	78	12	voluntarily	voluntarily	ADV
dpc-2345	78	13	donated	donate	VERB
dpc-2345	78	14	by	by	ADP
dpc-2345	78	15	the	the	DET
dpc-2345	78	16	participants	participant	NOUN
dpc-2345	78	17	.	.	PUNCT
dpc-2345	79	1	after	after	ADP
dpc-2345	79	2	collecting	collect	VERB
dpc-2345	79	3	nail	nail	NOUN
dpc-2345	79	4	samples	sample	NOUN
dpc-2345	79	5	,	,	PUNCT
dpc-2345	79	6	each	each	DET
dpc-2345	79	7	nail	nail	NOUN
dpc-2345	79	8	was	be	AUX
dpc-2345	79	9	cut	cut	VERB
dpc-2345	79	10	into	into	ADP
dpc-2345	79	11	table	table	NOUN
dpc-2345	79	12	1	1	NUM
dpc-2345	79	13	.	.	PUNCT
dpc-2345	80	1	some	some	DET
dpc-2345	80	2	important	important	ADJ
dpc-2345	80	3	properties	property	NOUN
dpc-2345	80	4	of	of	ADP
dpc-2345	80	5	studied	studied	ADJ
dpc-2345	80	6	terpenes	terpene	NOUN
dpc-2345	80	7	.	.	PUNCT
dpc-2345	81	1	name	name	VERB
dpc-2345	81	2	molecular	molecular	ADJ
dpc-2345	81	3	formula	formula	NOUN
dpc-2345	81	4	structure	structure	NOUN
dpc-2345	81	5	type	type	NOUN
dpc-2345	81	6	log	log	NOUN
dpc-2345	81	7	p	p	NOUN
dpc-2345	81	8	boiling	boiling	NOUN
dpc-2345	81	9	point	point	NOUN
dpc-2345	81	10	lavandulol	lavandulol	PROPN
dpc-2345	81	11	acetate	acetate	PROPN
dpc-2345	81	12	c12h20o2	c12h20o2	PROPN
dpc-2345	81	13	monoterpene	monoterpene	VERB
dpc-2345	81	14	3.1	3.1	NUM
dpc-2345	81	15	90	90	NUM
dpc-2345	81	16	oc	oc	ADP
dpc-2345	81	17	safranal	safranal	ADJ
dpc-2345	81	18	c10h14o	c10h14o	NUM
dpc-2345	81	19	aldehydic	aldehydic	ADJ
dpc-2345	81	20	terpene	terpene	NOUN
dpc-2345	81	21	2.1	2.1	NUM
dpc-2345	81	22	70	70	NUM
dpc-2345	81	23	oc	oc	NOUN
dpc-2345	82	1	rose	rise	VERB
dpc-2345	82	2	oxide	oxide	NOUN
dpc-2345	82	3	c10h18o	c10h18o	NOUN
dpc-2345	82	4	monoterpene	monoterpene	VERB
dpc-2345	82	5	2.9	2.9	NUM
dpc-2345	82	6	71	71	NUM
dpc-2345	82	7	-	-	SYM
dpc-2345	82	8	73	73	NUM
dpc-2345	82	9	oc	oc	PROPN
dpc-2345	82	10	limonene	limonene	PROPN
dpc-2345	82	11	c10h16	c10h16	PROPN
dpc-2345	82	12	monoterpene	monoterpene	VERB
dpc-2345	82	13	3.4	3.4	NUM
dpc-2345	82	14	175	175	NUM
dpc-2345	82	15	oc	oc	PRON
dpc-2345	82	16	3	3	NUM
dpc-2345	82	17	-	-	PUNCT
dpc-2345	82	18	methyl-2	methyl-2	VERB
dpc-2345	82	19	-	-	PUNCT
dpc-2345	82	20	buten1	buten1	ADJ
dpc-2345	82	21	-	-	PUNCT
dpc-2345	82	22	ol	ol	ADJ
dpc-2345	82	23	or	or	CCONJ
dpc-2345	82	24	prenol	prenol	ADJ
dpc-2345	82	25	c5h10o	c5h10o	PROPN
dpc-2345	82	26	monoterpene	monoterpene	VERB
dpc-2345	82	27	0.91	0.91	NUM
dpc-2345	82	28	140	140	NUM
dpc-2345	82	29	oc	oc	ADP
dpc-2345	82	30	linalool	linalool	NOUN
dpc-2345	82	31	c10h18o	c10h18o	NOUN
dpc-2345	82	32	monoterpene	monoterpene	VERB
dpc-2345	82	33	2.7	2.7	NUM
dpc-2345	82	34	198.5	198.5	NUM
dpc-2345	82	35	oc	oc	PART
dpc-2345	82	36	4	4	NUM
dpc-2345	82	37	review	review	NOUN
dpc-2345	82	38	|	|	ADV
dpc-2345	82	39	dermatol	dermatol	ADJ
dpc-2345	82	40	pract	pract	NOUN
dpc-2345	82	41	concept	concept	NOUN
dpc-2345	82	42	.	.	PUNCT
dpc-2345	83	1	2022;12(4):e2022202	2022;12(4):e2022202	NUM
dpc-2345	83	2	the	the	DET
dpc-2345	83	3	concentration	concentration	NOUN
dpc-2345	83	4	of	of	ADP
dpc-2345	83	5	terbinafine	terbinafine	NOUN
dpc-2345	83	6	in	in	ADP
dpc-2345	83	7	nail	nail	NOUN
dpc-2345	83	8	samples	sample	NOUN
dpc-2345	83	9	was	be	AUX
dpc-2345	83	10	determined	determine	VERB
dpc-2345	83	11	from	from	ADP
dpc-2345	83	12	the	the	DET
dpc-2345	83	13	calibration	calibration	NOUN
dpc-2345	83	14	curve	curve	NOUN
dpc-2345	83	15	plotted	plot	VERB
dpc-2345	83	16	using	use	VERB
dpc-2345	83	17	the	the	DET
dpc-2345	83	18	above	above	ADJ
dpc-2345	83	19	five	five	NUM
dpc-2345	83	20	calibrators	calibrator	NOUN
dpc-2345	83	21	.	.	PUNCT
dpc-2345	84	1	statistical	statistical	ADJ
dpc-2345	84	2	analysis	analysis	NOUN
dpc-2345	84	3	the	the	DET
dpc-2345	84	4	outcome	outcome	NOUN
dpc-2345	84	5	result	result	NOUN
dpc-2345	84	6	of	of	ADP
dpc-2345	84	7	the	the	DET
dpc-2345	84	8	terbinafine	terbinafine	ADJ
dpc-2345	84	9	extraction	extraction	NOUN
dpc-2345	84	10	from	from	ADP
dpc-2345	84	11	the	the	DET
dpc-2345	84	12	nail	nail	NOUN
dpc-2345	84	13	samples	sample	NOUN
dpc-2345	84	14	of	of	ADP
dpc-2345	84	15	the	the	DET
dpc-2345	84	16	control	control	NOUN
dpc-2345	84	17	solution	solution	NOUN
dpc-2345	84	18	(	(	PUNCT
dpc-2345	84	19	without	without	ADP
dpc-2345	84	20	terpene	terpene	NOUN
dpc-2345	84	21	)	)	PUNCT
dpc-2345	84	22	was	be	AUX
dpc-2345	84	23	compared	compare	VERB
dpc-2345	84	24	individually	individually	ADV
dpc-2345	84	25	with	with	ADP
dpc-2345	84	26	the	the	DET
dpc-2345	84	27	results	result	NOUN
dpc-2345	84	28	acquired	acquire	VERB
dpc-2345	84	29	with	with	ADP
dpc-2345	84	30	each	each	DET
dpc-2345	84	31	test	test	NOUN
dpc-2345	84	32	solution	solution	NOUN
dpc-2345	84	33	(	(	PUNCT
dpc-2345	84	34	carrying	carry	VERB
dpc-2345	84	35	6	6	NUM
dpc-2345	84	36	%	%	NOUN
dpc-2345	84	37	terpene	terpene	NOUN
dpc-2345	84	38	)	)	PUNCT
dpc-2345	84	39	by	by	ADP
dpc-2345	84	40	statistical	statistical	ADJ
dpc-2345	84	41	analysis	analysis	NOUN
dpc-2345	84	42	.	.	PUNCT
dpc-2345	85	1	shapiro	shapiro	PROPN
dpc-2345	85	2	-	-	PUNCT
dpc-2345	85	3	wilk	wilk	PROPN
dpc-2345	85	4	test	test	NOUN
dpc-2345	85	5	was	be	AUX
dpc-2345	85	6	employed	employ	VERB
dpc-2345	85	7	to	to	PART
dpc-2345	85	8	determine	determine	VERB
dpc-2345	85	9	the	the	DET
dpc-2345	85	10	normal	normal	ADJ
dpc-2345	85	11	distribution	distribution	NOUN
dpc-2345	85	12	of	of	ADP
dpc-2345	85	13	variables	variable	NOUN
dpc-2345	85	14	using	use	VERB
dpc-2345	85	15	sigmaplot	sigmaplot	NOUN
dpc-2345	85	16	v	v	ADP
dpc-2345	85	17	14.0	14.0	NUM
dpc-2345	85	18	software	software	NOUN
dpc-2345	85	19	.	.	PUNCT
dpc-2345	86	1	for	for	ADP
dpc-2345	86	2	comparing	compare	VERB
dpc-2345	86	3	the	the	DET
dpc-2345	86	4	quantitative	quantitative	ADJ
dpc-2345	86	5	variables	variable	NOUN
dpc-2345	86	6	with	with	ADP
dpc-2345	86	7	normally	normally	ADV
dpc-2345	86	8	distributed	distribute	VERB
dpc-2345	86	9	and	and	CCONJ
dpc-2345	86	10	non	non	ADJ
dpc-2345	86	11	-	-	ADJ
dpc-2345	86	12	normally	normally	ADV
dpc-2345	86	13	distributed	distribute	VERB
dpc-2345	86	14	quantitative	quantitative	ADJ
dpc-2345	86	15	variables	variable	NOUN
dpc-2345	86	16	,	,	PUNCT
dpc-2345	86	17	paired	pair	VERB
dpc-2345	86	18	t	t	NOUN
dpc-2345	86	19	-	-	PUNCT
dpc-2345	86	20	test	test	NOUN
dpc-2345	86	21	and	and	CCONJ
dpc-2345	86	22	mann	mann	PROPN
dpc-2345	86	23	-	-	PUNCT
dpc-2345	86	24	whitney	whitney	PROPN
dpc-2345	86	25	u	u	PROPN
dpc-2345	86	26	test	test	NOUN
dpc-2345	86	27	were	be	AUX
dpc-2345	86	28	employed	employ	VERB
dpc-2345	86	29	,	,	PUNCT
dpc-2345	86	30	respectively	respectively	ADV
dpc-2345	86	31	,	,	PUNCT
dpc-2345	86	32	and	and	CCONJ
dpc-2345	86	33	a	a	DET
dpc-2345	86	34	p	p	NOUN
dpc-2345	86	35	value	value	NOUN
dpc-2345	86	36	<	<	X
dpc-2345	86	37	0.05	0.05	NUM
dpc-2345	86	38	was	be	AUX
dpc-2345	86	39	considered	consider	VERB
dpc-2345	86	40	statistically	statistically	ADV
dpc-2345	86	41	significant	significant	ADJ
dpc-2345	86	42	.	.	PUNCT
dpc-2345	87	1	results	result	VERB
dpc-2345	87	2	sample	sample	NOUN
dpc-2345	87	3	preparation	preparation	NOUN
dpc-2345	87	4	and	and	CCONJ
dpc-2345	87	5	drug	drug	NOUN
dpc-2345	87	6	stability	stability	NOUN
dpc-2345	87	7	to	to	PART
dpc-2345	87	8	assess	assess	VERB
dpc-2345	87	9	the	the	DET
dpc-2345	87	10	transungual	transungual	ADJ
dpc-2345	87	11	permeation	permeation	NOUN
dpc-2345	87	12	of	of	ADP
dpc-2345	87	13	the	the	DET
dpc-2345	87	14	drugs	drug	NOUN
dpc-2345	87	15	,	,	PUNCT
dpc-2345	87	16	the	the	DET
dpc-2345	87	17	nail	nail	NOUN
dpc-2345	87	18	samples	sample	NOUN
dpc-2345	87	19	of	of	ADP
dpc-2345	87	20	the	the	DET
dpc-2345	87	21	human	human	ADJ
dpc-2345	87	22	volunteers	volunteer	NOUN
dpc-2345	87	23	were	be	AUX
dpc-2345	87	24	digested	digest	VERB
dpc-2345	87	25	in	in	ADP
dpc-2345	87	26	various	various	ADJ
dpc-2345	87	27	media	medium	NOUN
dpc-2345	87	28	[	[	X
dpc-2345	87	29	25	25	NUM
dpc-2345	87	30	]	]	PUNCT
dpc-2345	87	31	.	.	PUNCT
dpc-2345	88	1	alkaline	alkaline	NOUN
dpc-2345	88	2	,	,	PUNCT
dpc-2345	88	3	acidic	acidic	ADJ
dpc-2345	88	4	and	and	CCONJ
dpc-2345	88	5	methanolic	methanolic	NOUN
dpc-2345	88	6	digestion	digestion	NOUN
dpc-2345	88	7	methods	method	NOUN
dpc-2345	88	8	were	be	AUX
dpc-2345	88	9	used	use	VERB
dpc-2345	88	10	to	to	PART
dpc-2345	88	11	hydrolyze	hydrolyze	VERB
dpc-2345	88	12	the	the	DET
dpc-2345	88	13	nail	nail	NOUN
dpc-2345	88	14	matrix	matrix	NOUN
dpc-2345	88	15	.	.	PUNCT
dpc-2345	89	1	various	various	ADJ
dpc-2345	89	2	digestion	digestion	NOUN
dpc-2345	89	3	procedures	procedure	NOUN
dpc-2345	89	4	have	have	AUX
dpc-2345	89	5	been	be	AUX
dpc-2345	89	6	reported	report	VERB
dpc-2345	89	7	,	,	PUNCT
dpc-2345	89	8	including	include	VERB
dpc-2345	89	9	acid	acid	ADJ
dpc-2345	89	10	digestion	digestion	NOUN
dpc-2345	89	11	by	by	ADP
dpc-2345	89	12	hcl	hcl	PROPN
dpc-2345	89	13	(	(	PUNCT
dpc-2345	89	14	0.1	0.1	NUM
dpc-2345	89	15	–	–	PUNCT
dpc-2345	89	16	5.0	5.0	NUM
dpc-2345	89	17	m	m	NOUN
dpc-2345	89	18	)	)	PUNCT
dpc-2345	89	19	,	,	PUNCT
dpc-2345	89	20	basic	basic	ADJ
dpc-2345	89	21	digestion	digestion	NOUN
dpc-2345	89	22	by	by	ADP
dpc-2345	89	23	naoh	naoh	NOUN
dpc-2345	89	24	(	(	PUNCT
dpc-2345	89	25	1	1	NUM
dpc-2345	89	26	-	-	SYM
dpc-2345	89	27	10	10	NUM
dpc-2345	89	28	m	m	NOUN
dpc-2345	89	29	)	)	PUNCT
dpc-2345	89	30	,	,	PUNCT
dpc-2345	89	31	digestion	digestion	NOUN
dpc-2345	89	32	by	by	ADP
dpc-2345	89	33	nitric	nitric	ADJ
dpc-2345	89	34	oxide	oxide	NOUN
dpc-2345	89	35	(	(	PUNCT
dpc-2345	89	36	5	5	NUM
dpc-2345	89	37	%	%	NOUN
dpc-2345	89	38	–	–	PUNCT
dpc-2345	89	39	60	60	NUM
dpc-2345	89	40	%	%	NOUN
dpc-2345	89	41	)	)	PUNCT
dpc-2345	89	42	,	,	PUNCT
dpc-2345	89	43	their	their	PRON
dpc-2345	89	44	combination	combination	NOUN
dpc-2345	89	45	with	with	ADP
dpc-2345	89	46	methanol	methanol	NOUN
dpc-2345	89	47	and	and	CCONJ
dpc-2345	89	48	hydrogen	hydrogen	NOUN
dpc-2345	89	49	peroxide	peroxide	NOUN
dpc-2345	89	50	at	at	ADP
dpc-2345	89	51	a	a	DET
dpc-2345	89	52	temperature	temperature	NOUN
dpc-2345	89	53	between	between	ADP
dpc-2345	89	54	25	25	NUM
dpc-2345	89	55	-	-	PUNCT
dpc-2345	89	56	600c	600c	NOUN
dpc-2345	89	57	and	and	CCONJ
dpc-2345	89	58	digestion	digestion	NOUN
dpc-2345	89	59	with	with	ADP
dpc-2345	89	60	benzyltrimethyl	benzyltrimethyl	PROPN
dpc-2345	89	61	ammonium	ammonium	NOUN
dpc-2345	89	62	hydroxide	hydroxide	NOUN
dpc-2345	89	63	.	.	PUNCT
dpc-2345	90	1	stability	stability	NOUN
dpc-2345	90	2	of	of	ADP
dpc-2345	90	3	terbinafine	terbinafine	NOUN
dpc-2345	90	4	was	be	AUX
dpc-2345	90	5	determined	determine	VERB
dpc-2345	90	6	with	with	ADP
dpc-2345	90	7	the	the	DET
dpc-2345	90	8	above	above	ADJ
dpc-2345	90	9	methods	method	NOUN
dpc-2345	90	10	(	(	PUNCT
dpc-2345	90	11	data	datum	NOUN
dpc-2345	90	12	not	not	PART
dpc-2345	90	13	shown	show	VERB
dpc-2345	90	14	)	)	PUNCT
dpc-2345	90	15	;	;	PUNCT
dpc-2345	90	16	eventually	eventually	ADV
dpc-2345	90	17	basic	basic	ADJ
dpc-2345	90	18	digestion	digestion	NOUN
dpc-2345	90	19	by	by	ADP
dpc-2345	90	20	naoh	naoh	NOUN
dpc-2345	90	21	(	(	PUNCT
dpc-2345	90	22	0.5	0.5	NUM
dpc-2345	90	23	m	m	NOUN
dpc-2345	90	24	)	)	PUNCT
dpc-2345	90	25	for	for	ADP
dpc-2345	90	26	16	16	NUM
dpc-2345	90	27	hours	hour	NOUN
dpc-2345	90	28	at	at	ADP
dpc-2345	90	29	room	room	NOUN
dpc-2345	90	30	temperature	temperature	NOUN
dpc-2345	90	31	was	be	AUX
dpc-2345	90	32	found	find	VERB
dpc-2345	90	33	as	as	ADP
dpc-2345	90	34	the	the	DET
dpc-2345	90	35	best	good	ADJ
dpc-2345	90	36	approach	approach	NOUN
dpc-2345	90	37	to	to	PART
dpc-2345	90	38	digest	digest	VERB
dpc-2345	90	39	the	the	DET
dpc-2345	90	40	nail	nail	NOUN
dpc-2345	90	41	samples	sample	NOUN
dpc-2345	90	42	.	.	PUNCT
dpc-2345	91	1	the	the	DET
dpc-2345	91	2	recovery	recovery	NOUN
dpc-2345	91	3	of	of	ADP
dpc-2345	91	4	terbinafine	terbinafine	NOUN
dpc-2345	91	5	by	by	ADP
dpc-2345	91	6	applying	apply	VERB
dpc-2345	91	7	this	this	DET
dpc-2345	91	8	method	method	NOUN
dpc-2345	91	9	was	be	AUX
dpc-2345	91	10	found	find	VERB
dpc-2345	91	11	to	to	PART
dpc-2345	91	12	be	be	AUX
dpc-2345	91	13	30.7	30.7	NUM
dpc-2345	91	14	%	%	NOUN
dpc-2345	91	15	.	.	PUNCT
dpc-2345	92	1	ex	ex	ADJ
dpc-2345	92	2	-	-	ADJ
dpc-2345	92	3	vivo	vivo	ADJ
dpc-2345	92	4	nail	nail	NOUN
dpc-2345	92	5	penetration	penetration	NOUN
dpc-2345	92	6	and	and	CCONJ
dpc-2345	92	7	statistical	statistical	ADJ
dpc-2345	92	8	analysis	analysis	NOUN
dpc-2345	92	9	the	the	DET
dpc-2345	92	10	experimental	experimental	ADJ
dpc-2345	92	11	data	datum	NOUN
dpc-2345	92	12	from	from	ADP
dpc-2345	92	13	ex	ex	ADJ
dpc-2345	92	14	-	-	ADJ
dpc-2345	92	15	vivo	vivo	ADJ
dpc-2345	92	16	nail	nail	NOUN
dpc-2345	92	17	penetration	penetration	NOUN
dpc-2345	92	18	studies	study	NOUN
dpc-2345	92	19	and	and	CCONJ
dpc-2345	92	20	statistical	statistical	ADJ
dpc-2345	92	21	analysis	analysis	NOUN
dpc-2345	92	22	are	be	AUX
dpc-2345	92	23	presented	present	VERB
dpc-2345	92	24	in	in	ADP
dpc-2345	92	25	table	table	NOUN
dpc-2345	92	26	2	2	NUM
dpc-2345	92	27	and	and	CCONJ
dpc-2345	92	28	hplc	hplc	NOUN
dpc-2345	92	29	chromatograms	chromatogram	NOUN
dpc-2345	92	30	of	of	ADP
dpc-2345	92	31	drug	drug	NOUN
dpc-2345	92	32	-	-	PUNCT
dpc-2345	92	33	free	free	ADJ
dpc-2345	92	34	(	(	PUNCT
dpc-2345	92	35	blank	blank	ADJ
dpc-2345	92	36	)	)	PUNCT
dpc-2345	92	37	,	,	PUNCT
dpc-2345	92	38	calibrator	calibrator	NOUN
dpc-2345	92	39	(	(	PUNCT
dpc-2345	92	40	standard	standard	ADJ
dpc-2345	92	41	terbinafine	terbinafine	NOUN
dpc-2345	92	42	)	)	PUNCT
dpc-2345	92	43	and	and	CCONJ
dpc-2345	92	44	sample	sample	NOUN
dpc-2345	92	45	solution	solution	NOUN
dpc-2345	92	46	(	(	PUNCT
dpc-2345	92	47	terpene	terpene	NOUN
dpc-2345	92	48	spiked	spike	VERB
dpc-2345	92	49	)	)	PUNCT
dpc-2345	92	50	are	be	AUX
dpc-2345	92	51	shown	show	VERB
dpc-2345	92	52	in	in	ADP
dpc-2345	92	53	figure	figure	NOUN
dpc-2345	92	54	1	1	NUM
dpc-2345	92	55	.	.	PUNCT
dpc-2345	93	1	the	the	DET
dpc-2345	93	2	concentration	concentration	NOUN
dpc-2345	93	3	of	of	ADP
dpc-2345	93	4	terbinafine	terbinafine	NOUN
dpc-2345	93	5	in	in	ADP
dpc-2345	93	6	nail	nail	NOUN
dpc-2345	93	7	samples	sample	NOUN
dpc-2345	93	8	of	of	ADP
dpc-2345	93	9	control	control	NOUN
dpc-2345	93	10	,	,	PUNCT
dpc-2345	93	11	lavandulol	lavandulol	ADJ
dpc-2345	93	12	,	,	PUNCT
dpc-2345	93	13	safranal	safranal	ADJ
dpc-2345	93	14	,	,	PUNCT
dpc-2345	93	15	rose	rise	VERB
dpc-2345	93	16	oxide	oxide	NOUN
dpc-2345	93	17	,	,	PUNCT
dpc-2345	93	18	limonene	limonene	NOUN
dpc-2345	93	19	,	,	PUNCT
dpc-2345	93	20	3	3	NUM
dpc-2345	93	21	-	-	PUNCT
dpc-2345	93	22	methyl-2butene-1	methyl-2butene-1	NOUN
dpc-2345	93	23	-	-	NOUN
dpc-2345	93	24	ol	ol	ADJ
dpc-2345	93	25	,	,	PUNCT
dpc-2345	93	26	and	and	CCONJ
dpc-2345	93	27	linalool	linalool	NOUN
dpc-2345	93	28	was	be	AUX
dpc-2345	93	29	found	find	VERB
dpc-2345	93	30	ranging	range	VERB
dpc-2345	93	31	from	from	ADP
dpc-2345	93	32	3.094	3.094	NUM
dpc-2345	93	33	to	to	ADP
dpc-2345	93	34	3.445	3.445	NUM
dpc-2345	93	35	µg	µg	NOUN
dpc-2345	93	36	/	/	SYM
dpc-2345	93	37	mg	mg	PROPN
dpc-2345	93	38	(	(	PUNCT
dpc-2345	93	39	3.280	3.280	NUM
dpc-2345	93	40	±	±	NUM
dpc-2345	93	41	0.122	0.122	NUM
dpc-2345	93	42	)	)	PUNCT
dpc-2345	93	43	,	,	PUNCT
dpc-2345	93	44	3.372	3.372	NUM
dpc-2345	93	45	to	to	ADP
dpc-2345	93	46	3.548	3.548	NUM
dpc-2345	93	47	µg	µg	NOUN
dpc-2345	93	48	/	/	SYM
dpc-2345	93	49	mg	mg	PROPN
dpc-2345	93	50	(	(	PUNCT
dpc-2345	93	51	3.486	3.486	NUM
dpc-2345	93	52	±	±	NUM
dpc-2345	93	53	0.051	0.051	NUM
dpc-2345	93	54	)	)	PUNCT
dpc-2345	93	55	,	,	PUNCT
dpc-2345	93	56	3.419	3.419	NUM
dpc-2345	93	57	to	to	ADP
dpc-2345	93	58	3.774	3.774	NUM
dpc-2345	93	59	µg	µg	NOUN
dpc-2345	93	60	/	/	SYM
dpc-2345	93	61	mg	mg	PROPN
dpc-2345	93	62	(	(	PUNCT
dpc-2345	93	63	3.601	3.601	NUM
dpc-2345	93	64	±	±	NUM
dpc-2345	93	65	0.115	0.115	NUM
dpc-2345	93	66	)	)	PUNCT
dpc-2345	93	67	,	,	PUNCT
dpc-2345	93	68	4.469	4.469	NUM
dpc-2345	93	69	to	to	ADP
dpc-2345	93	70	4.682	4.682	NUM
dpc-2345	93	71	µg	µg	NOUN
dpc-2345	93	72	/	/	SYM
dpc-2345	93	73	mg	mg	PROPN
dpc-2345	93	74	(	(	PUNCT
dpc-2345	93	75	4.554	4.554	NUM
dpc-2345	93	76	±	±	NUM
dpc-2345	93	77	0.061	0.061	NUM
dpc-2345	93	78	)	)	PUNCT
dpc-2345	93	79	,	,	PUNCT
dpc-2345	93	80	3.502	3.502	NUM
dpc-2345	93	81	to	to	ADP
dpc-2345	93	82	3.605	3.605	NUM
dpc-2345	93	83	µg	µg	NOUN
dpc-2345	93	84	/	/	SYM
dpc-2345	93	85	mg	mg	PROPN
dpc-2345	93	86	(	(	PUNCT
dpc-2345	93	87	3.551	3.551	NUM
dpc-2345	93	88	±	±	NUM
dpc-2345	93	89	0.038	0.038	NUM
dpc-2345	93	90	)	)	PUNCT
dpc-2345	93	91	,	,	PUNCT
dpc-2345	93	92	4.386	4.386	NUM
dpc-2345	93	93	to	to	PART
dpc-2345	93	94	4.538	4.538	NUM
dpc-2345	93	95	µg	µg	NOUN
dpc-2345	93	96	/	/	SYM
dpc-2345	93	97	mg	mg	PROPN
dpc-2345	93	98	(	(	PUNCT
dpc-2345	93	99	4.463	4.463	NUM
dpc-2345	93	100	±	±	NUM
dpc-2345	93	101	0.041	0.041	NUM
dpc-2345	93	102	)	)	PUNCT
dpc-2345	93	103	and	and	CCONJ
dpc-2345	93	104	4.708	4.708	NUM
dpc-2345	93	105	to	to	ADP
dpc-2345	93	106	4.796	4.796	NUM
dpc-2345	93	107	µg	µg	NOUN
dpc-2345	93	108	/	/	SYM
dpc-2345	93	109	mg	mg	PROPN
dpc-2345	93	110	(	(	PUNCT
dpc-2345	93	111	4.748	4.748	NUM
dpc-2345	93	112	±	±	NUM
dpc-2345	93	113	0.028	0.028	NUM
dpc-2345	93	114	)	)	PUNCT
dpc-2345	93	115	respectively	respectively	ADV
dpc-2345	93	116	.	.	PUNCT
dpc-2345	94	1	after	after	ADP
dpc-2345	94	2	employing	employ	VERB
dpc-2345	94	3	mann	mann	PROPN
dpc-2345	94	4	-	-	PUNCT
dpc-2345	94	5	whitney	whitney	PROPN
dpc-2345	94	6	u	u	PROPN
dpc-2345	94	7	test	test	NOUN
dpc-2345	94	8	,	,	PUNCT
dpc-2345	94	9	the	the	DET
dpc-2345	94	10	results	result	NOUN
dpc-2345	94	11	showed	show	VERB
dpc-2345	94	12	a	a	DET
dpc-2345	94	13	significant	significant	ADJ
dpc-2345	94	14	small	small	ADJ
dpc-2345	94	15	pieces	piece	NOUN
dpc-2345	94	16	;	;	PUNCT
dpc-2345	94	17	25	25	NUM
dpc-2345	94	18	mg	mg	NOUN
dpc-2345	94	19	of	of	ADP
dpc-2345	94	20	nail	nail	NOUN
dpc-2345	94	21	sample	sample	NOUN
dpc-2345	94	22	was	be	AUX
dpc-2345	94	23	used	use	VERB
dpc-2345	94	24	for	for	ADP
dpc-2345	94	25	each	each	DET
dpc-2345	94	26	experiment	experiment	NOUN
dpc-2345	94	27	[	[	X
dpc-2345	94	28	25	25	NUM
dpc-2345	94	29	]	]	PUNCT
dpc-2345	94	30	.	.	PUNCT
dpc-2345	95	1	to	to	PART
dpc-2345	95	2	remove	remove	VERB
dpc-2345	95	3	the	the	DET
dpc-2345	95	4	adhered	adhere	VERB
dpc-2345	95	5	dirt	dirt	NOUN
dpc-2345	95	6	from	from	ADP
dpc-2345	95	7	the	the	DET
dpc-2345	95	8	surface	surface	NOUN
dpc-2345	95	9	and	and	CCONJ
dpc-2345	95	10	prevent	prevent	VERB
dpc-2345	95	11	any	any	DET
dpc-2345	95	12	interference	interference	NOUN
dpc-2345	95	13	in	in	ADP
dpc-2345	95	14	the	the	DET
dpc-2345	95	15	study	study	NOUN
dpc-2345	95	16	,	,	PUNCT
dpc-2345	95	17	20	20	NUM
dpc-2345	95	18	ml	ml	NOUN
dpc-2345	95	19	of	of	ADP
dpc-2345	95	20	water	water	NOUN
dpc-2345	95	21	was	be	AUX
dpc-2345	95	22	added	add	VERB
dpc-2345	95	23	to	to	ADP
dpc-2345	95	24	the	the	DET
dpc-2345	95	25	nail	nail	NOUN
dpc-2345	95	26	samples	sample	NOUN
dpc-2345	95	27	to	to	PART
dpc-2345	95	28	digest	digest	VERB
dpc-2345	95	29	for	for	ADP
dpc-2345	95	30	20	20	NUM
dpc-2345	95	31	minutes	minute	NOUN
dpc-2345	95	32	.	.	PUNCT
dpc-2345	96	1	then	then	ADV
dpc-2345	96	2	,	,	PUNCT
dpc-2345	96	3	nail	nail	NOUN
dpc-2345	96	4	samples	sample	NOUN
dpc-2345	96	5	were	be	AUX
dpc-2345	96	6	washed	wash	VERB
dpc-2345	96	7	with	with	ADP
dpc-2345	96	8	methanol	methanol	NOUN
dpc-2345	96	9	three	three	NUM
dpc-2345	96	10	times	time	NOUN
dpc-2345	96	11	and	and	CCONJ
dpc-2345	96	12	then	then	ADV
dpc-2345	96	13	air	air	NOUN
dpc-2345	96	14	-	-	PUNCT
dpc-2345	96	15	dried	dry	VERB
dpc-2345	96	16	.	.	PUNCT
dpc-2345	97	1	further	far	ADV
dpc-2345	97	2	,	,	PUNCT
dpc-2345	97	3	the	the	DET
dpc-2345	97	4	nail	nail	NOUN
dpc-2345	97	5	samples	sample	NOUN
dpc-2345	97	6	were	be	AUX
dpc-2345	97	7	stored	store	VERB
dpc-2345	97	8	at	at	ADP
dpc-2345	97	9	a	a	DET
dpc-2345	97	10	room	room	NOUN
dpc-2345	97	11	temperature	temperature	NOUN
dpc-2345	97	12	in	in	ADP
dpc-2345	97	13	a	a	DET
dpc-2345	97	14	sealed	seal	VERB
dpc-2345	97	15	plastic	plastic	NOUN
dpc-2345	97	16	bags	bag	NOUN
dpc-2345	97	17	till	till	SCONJ
dpc-2345	97	18	analysis	analysis	NOUN
dpc-2345	97	19	.	.	PUNCT
dpc-2345	98	1	eight	eight	NUM
dpc-2345	98	2	propylene	propylene	NOUN
dpc-2345	98	3	tubes	tube	NOUN
dpc-2345	98	4	of	of	ADP
dpc-2345	98	5	2	2	NUM
dpc-2345	98	6	ml	ml	NOUN
dpc-2345	98	7	capacity	capacity	NOUN
dpc-2345	98	8	were	be	AUX
dpc-2345	98	9	taken	take	VERB
dpc-2345	98	10	and	and	CCONJ
dpc-2345	98	11	eight	eight	NUM
dpc-2345	98	12	aliquots	aliquot	NOUN
dpc-2345	98	13	(	(	PUNCT
dpc-2345	98	14	each	each	DET
dpc-2345	98	15	25	25	NUM
dpc-2345	98	16	mg	mg	NOUN
dpc-2345	98	17	)	)	PUNCT
dpc-2345	98	18	of	of	ADP
dpc-2345	98	19	nail	nail	NOUN
dpc-2345	98	20	samples	sample	NOUN
dpc-2345	98	21	of	of	ADP
dpc-2345	98	22	each	each	DET
dpc-2345	98	23	volunteer	volunteer	NOUN
dpc-2345	98	24	were	be	AUX
dpc-2345	98	25	transferred	transfer	VERB
dpc-2345	98	26	into	into	ADP
dpc-2345	98	27	it	it	PRON
dpc-2345	98	28	.	.	PUNCT
dpc-2345	99	1	one	one	NUM
dpc-2345	99	2	ml	ml	NOUN
dpc-2345	99	3	of	of	ADP
dpc-2345	99	4	a	a	DET
dpc-2345	99	5	drug	drug	NOUN
dpc-2345	99	6	-	-	PUNCT
dpc-2345	99	7	free	free	ADJ
dpc-2345	99	8	working	working	NOUN
dpc-2345	99	9	solution	solution	NOUN
dpc-2345	99	10	was	be	AUX
dpc-2345	99	11	taken	take	VERB
dpc-2345	99	12	in	in	ADP
dpc-2345	99	13	the	the	DET
dpc-2345	99	14	first	first	ADJ
dpc-2345	99	15	tube	tube	NOUN
dpc-2345	99	16	as	as	ADP
dpc-2345	99	17	blank	blank	ADJ
dpc-2345	99	18	sample	sample	NOUN
dpc-2345	99	19	(	(	PUNCT
dpc-2345	99	20	solution	solution	NOUN
dpc-2345	99	21	 	 	SPACE
dpc-2345	99	22	a	a	NOUN
dpc-2345	99	23	)	)	PUNCT
dpc-2345	99	24	.	.	PUNCT
dpc-2345	100	1	to	to	PART
dpc-2345	100	2	determine	determine	VERB
dpc-2345	100	3	the	the	DET
dpc-2345	100	4	effect	effect	NOUN
dpc-2345	100	5	of	of	ADP
dpc-2345	100	6	terpenes	terpene	NOUN
dpc-2345	100	7	on	on	ADP
dpc-2345	100	8	the	the	DET
dpc-2345	100	9	penetration	penetration	NOUN
dpc-2345	100	10	of	of	ADP
dpc-2345	100	11	terbinafine	terbinafine	NOUN
dpc-2345	100	12	across	across	ADP
dpc-2345	100	13	the	the	DET
dpc-2345	100	14	nail	nail	NOUN
dpc-2345	100	15	samples	sample	NOUN
dpc-2345	100	16	,	,	PUNCT
dpc-2345	100	17	1	1	NUM
dpc-2345	100	18	ml	ml	NOUN
dpc-2345	100	19	each	each	PRON
dpc-2345	100	20	of	of	ADP
dpc-2345	100	21	blank	blank	ADJ
dpc-2345	100	22	solution	solution	NOUN
dpc-2345	100	23	a	a	DET
dpc-2345	100	24	and	and	CCONJ
dpc-2345	100	25	working	working	NOUN
dpc-2345	100	26	solutions	solution	NOUN
dpc-2345	100	27	b	b	PROPN
dpc-2345	100	28	,	,	PUNCT
dpc-2345	100	29	c	c	NOUN
dpc-2345	100	30	,	,	PUNCT
dpc-2345	100	31	d	d	NOUN
dpc-2345	100	32	,	,	PUNCT
dpc-2345	100	33	e	e	NOUN
dpc-2345	100	34	,	,	PUNCT
dpc-2345	100	35	f	f	X
dpc-2345	100	36	,	,	PUNCT
dpc-2345	100	37	and	and	CCONJ
dpc-2345	100	38	g	g	PROPN
dpc-2345	100	39	was	be	AUX
dpc-2345	100	40	added	add	VERB
dpc-2345	100	41	to	to	ADP
dpc-2345	100	42	the	the	DET
dpc-2345	100	43	remaining	remain	VERB
dpc-2345	100	44	tubes	tube	NOUN
dpc-2345	100	45	and	and	CCONJ
dpc-2345	100	46	kept	keep	VERB
dpc-2345	100	47	at	at	ADP
dpc-2345	100	48	room	room	NOUN
dpc-2345	100	49	temperature	temperature	NOUN
dpc-2345	100	50	for	for	ADP
dpc-2345	100	51	48	48	NUM
dpc-2345	100	52	hours	hour	NOUN
dpc-2345	100	53	.	.	PUNCT
dpc-2345	101	1	further	far	ADV
dpc-2345	101	2	,	,	PUNCT
dpc-2345	101	3	nail	nail	NOUN
dpc-2345	101	4	samples	sample	NOUN
dpc-2345	101	5	were	be	AUX
dpc-2345	101	6	sonicated	sonicate	VERB
dpc-2345	101	7	for	for	ADP
dpc-2345	101	8	15	15	NUM
dpc-2345	101	9	minutes	minute	NOUN
dpc-2345	101	10	with	with	ADP
dpc-2345	101	11	10	10	NUM
dpc-2345	101	12	ml	ml	NOUN
dpc-2345	101	13	methanol	methanol	NOUN
dpc-2345	101	14	thrice	thrice	NOUN
dpc-2345	101	15	to	to	PART
dpc-2345	101	16	remove	remove	VERB
dpc-2345	101	17	the	the	DET
dpc-2345	101	18	adhered	adhere	VERB
dpc-2345	101	19	drug	drug	NOUN
dpc-2345	101	20	residue	residue	NOUN
dpc-2345	101	21	from	from	ADP
dpc-2345	101	22	the	the	DET
dpc-2345	101	23	surface	surface	NOUN
dpc-2345	101	24	.	.	PUNCT
dpc-2345	102	1	further	far	ADV
dpc-2345	102	2	,	,	PUNCT
dpc-2345	102	3	the	the	DET
dpc-2345	102	4	samples	sample	NOUN
dpc-2345	102	5	were	be	AUX
dpc-2345	102	6	transferred	transfer	VERB
dpc-2345	102	7	to	to	ADP
dpc-2345	102	8	the	the	DET
dpc-2345	102	9	centrifuge	centrifuge	NOUN
dpc-2345	102	10	tubes	tube	NOUN
dpc-2345	102	11	.	.	PUNCT
dpc-2345	103	1	then	then	ADV
dpc-2345	103	2	,	,	PUNCT
dpc-2345	103	3	the	the	DET
dpc-2345	103	4	tubes	tube	NOUN
dpc-2345	103	5	were	be	AUX
dpc-2345	103	6	incubated	incubate	VERB
dpc-2345	103	7	after	after	ADP
dpc-2345	103	8	addition	addition	NOUN
dpc-2345	103	9	of	of	ADP
dpc-2345	103	10	1ml	1ml	NOUN
dpc-2345	103	11	of	of	ADP
dpc-2345	103	12	0.5	0.5	NUM
dpc-2345	103	13	m	m	NOUN
dpc-2345	103	14	naoh	naoh	NOUN
dpc-2345	103	15	for	for	ADP
dpc-2345	103	16	12	12	NUM
dpc-2345	103	17	hours	hour	NOUN
dpc-2345	103	18	to	to	PART
dpc-2345	103	19	digest	digest	VERB
dpc-2345	103	20	the	the	DET
dpc-2345	103	21	samples	sample	NOUN
dpc-2345	103	22	.	.	PUNCT
dpc-2345	104	1	the	the	DET
dpc-2345	104	2	samples	sample	NOUN
dpc-2345	104	3	were	be	AUX
dpc-2345	104	4	neutralized	neutralize	VERB
dpc-2345	104	5	by	by	ADP
dpc-2345	104	6	adding	add	VERB
dpc-2345	104	7	0.5	0.5	NUM
dpc-2345	104	8	m	m	PROPN
dpc-2345	104	9	hcl	hcl	NOUN
dpc-2345	104	10	solution	solution	NOUN
dpc-2345	104	11	.	.	PUNCT
dpc-2345	105	1	the	the	DET
dpc-2345	105	2	samples	sample	NOUN
dpc-2345	105	3	were	be	AUX
dpc-2345	105	4	then	then	ADV
dpc-2345	105	5	vortexed	vortexe	VERB
dpc-2345	105	6	for	for	ADP
dpc-2345	105	7	2	2	NUM
dpc-2345	105	8	minutes	minute	NOUN
dpc-2345	105	9	and	and	CCONJ
dpc-2345	105	10	centrifuged	centrifuge	VERB
dpc-2345	105	11	at	at	ADP
dpc-2345	105	12	6000	6000	NUM
dpc-2345	105	13	rpm	rpm	NOUN
dpc-2345	105	14	for	for	ADP
dpc-2345	105	15	20	20	NUM
dpc-2345	105	16	minutes	minute	NOUN
dpc-2345	105	17	.	.	PUNCT
dpc-2345	106	1	the	the	DET
dpc-2345	106	2	supernatant	supernatant	NOUN
dpc-2345	106	3	was	be	AUX
dpc-2345	106	4	collected	collect	VERB
dpc-2345	106	5	and	and	CCONJ
dpc-2345	106	6	the	the	DET
dpc-2345	106	7	concentration	concentration	NOUN
dpc-2345	106	8	of	of	ADP
dpc-2345	106	9	terbinafine	terbinafine	NOUN
dpc-2345	106	10	in	in	ADP
dpc-2345	106	11	20	20	NUM
dpc-2345	106	12	ul	ul	NOUN
dpc-2345	106	13	of	of	ADP
dpc-2345	106	14	each	each	DET
dpc-2345	106	15	solution	solution	NOUN
dpc-2345	106	16	was	be	AUX
dpc-2345	106	17	determined	determine	VERB
dpc-2345	106	18	by	by	ADP
dpc-2345	106	19	hplc	hplc	NOUN
dpc-2345	106	20	analysis	analysis	NOUN
dpc-2345	106	21	.	.	PUNCT
dpc-2345	107	1	stability	stability	NOUN
dpc-2345	107	2	of	of	ADP
dpc-2345	107	3	terbinafine	terbinafine	NOUN
dpc-2345	107	4	in	in	ADP
dpc-2345	107	5	the	the	DET
dpc-2345	107	6	digestion	digestion	NOUN
dpc-2345	107	7	procedure	procedure	NOUN
dpc-2345	107	8	in	in	ADP
dpc-2345	107	9	propylene	propylene	NOUN
dpc-2345	107	10	glycol	glycol	NOUN
dpc-2345	107	11	:	:	PUNCT
dpc-2345	107	12	tween	tween	NOUN
dpc-2345	107	13	80	80	NUM
dpc-2345	107	14	:	:	PUNCT
dpc-2345	107	15	ethanol	ethanol	NOUN
dpc-2345	107	16	:	:	PUNCT
dpc-2345	107	17	dimethyl	dimethyl	NOUN
dpc-2345	107	18	sulfoxide	sulfoxide	NOUN
dpc-2345	107	19	(	(	PUNCT
dpc-2345	107	20	30	30	NUM
dpc-2345	107	21	:	:	SYM
dpc-2345	107	22	3	3	NUM
dpc-2345	107	23	:	:	PUNCT
dpc-2345	107	24	62	62	NUM
dpc-2345	107	25	:	:	SYM
dpc-2345	107	26	5	5	NUM
dpc-2345	107	27	v	v	NOUN
dpc-2345	107	28	/	/	SYM
dpc-2345	107	29	v	v	NOUN
dpc-2345	107	30	)	)	PUNCT
dpc-2345	107	31	vehicle	vehicle	NOUN
dpc-2345	107	32	,	,	PUNCT
dpc-2345	107	33	1	1	NUM
dpc-2345	107	34	mg	mg	NUM
dpc-2345	107	35	/	/	SYM
dpc-2345	107	36	ml	ml	NOUN
dpc-2345	107	37	stock	stock	NOUN
dpc-2345	107	38	solution	solution	NOUN
dpc-2345	107	39	of	of	ADP
dpc-2345	107	40	terbinafine	terbinafine	NOUN
dpc-2345	107	41	was	be	AUX
dpc-2345	107	42	prepared	prepare	VERB
dpc-2345	107	43	.	.	PUNCT
dpc-2345	108	1	the	the	DET
dpc-2345	108	2	100ul	100ul	NOUN
dpc-2345	108	3	/	/	SYM
dpc-2345	108	4	ml	ml	NOUN
dpc-2345	108	5	solution	solution	NOUN
dpc-2345	108	6	of	of	ADP
dpc-2345	108	7	terbinafine	terbinafine	NOUN
dpc-2345	108	8	was	be	AUX
dpc-2345	108	9	prepared	prepare	VERB
dpc-2345	108	10	by	by	ADP
dpc-2345	108	11	diluting	dilute	VERB
dpc-2345	108	12	the	the	DET
dpc-2345	108	13	stock	stock	NOUN
dpc-2345	108	14	solution	solution	NOUN
dpc-2345	108	15	10	10	NUM
dpc-2345	108	16	times	time	NOUN
dpc-2345	108	17	in	in	ADP
dpc-2345	108	18	water	water	NOUN
dpc-2345	108	19	:	:	PUNCT
dpc-2345	108	20	methanol	methanol	NOUN
dpc-2345	108	21	(	(	PUNCT
dpc-2345	108	22	50:50	50:50	NUM
dpc-2345	108	23	,	,	PUNCT
dpc-2345	108	24	v	v	NOUN
dpc-2345	108	25	/	/	SYM
dpc-2345	108	26	v	v	NOUN
dpc-2345	108	27	)	)	PUNCT
dpc-2345	108	28	.	.	PUNCT
dpc-2345	109	1	further	far	ADV
dpc-2345	109	2	,	,	PUNCT
dpc-2345	109	3	two	two	NUM
dpc-2345	109	4	different	different	ADJ
dpc-2345	109	5	solutions	solution	NOUN
dpc-2345	109	6	were	be	AUX
dpc-2345	109	7	prepared	prepare	VERB
dpc-2345	109	8	using	use	VERB
dpc-2345	109	9	this	this	DET
dpc-2345	109	10	solution	solution	NOUN
dpc-2345	109	11	.	.	PUNCT
dpc-2345	110	1	first	first	ADV
dpc-2345	110	2	,	,	PUNCT
dpc-2345	110	3	an	an	DET
dpc-2345	110	4	aqueous	aqueous	ADJ
dpc-2345	110	5	solution	solution	NOUN
dpc-2345	110	6	of	of	ADP
dpc-2345	110	7	5	5	NUM
dpc-2345	110	8	 	 	SPACE
dpc-2345	110	9	µl	µl	NOUN
dpc-2345	110	10	/	/	SYM
dpc-2345	110	11	ml	ml	NOUN
dpc-2345	110	12	of	of	ADP
dpc-2345	110	13	terbinafine	terbinafine	NOUN
dpc-2345	110	14	was	be	AUX
dpc-2345	110	15	made	make	VERB
dpc-2345	110	16	by	by	ADP
dpc-2345	110	17	diluting	dilute	VERB
dpc-2345	110	18	the	the	DET
dpc-2345	110	19	above	above	ADJ
dpc-2345	110	20	solution	solution	NOUN
dpc-2345	110	21	20	20	NUM
dpc-2345	110	22	times	time	NOUN
dpc-2345	110	23	,	,	PUNCT
dpc-2345	110	24	and	and	CCONJ
dpc-2345	110	25	20	20	NUM
dpc-2345	110	26	µl	µl	NOUN
dpc-2345	110	27	of	of	ADP
dpc-2345	110	28	the	the	DET
dpc-2345	110	29	prepared	prepare	VERB
dpc-2345	110	30	aqueous	aqueous	ADJ
dpc-2345	110	31	solution	solution	NOUN
dpc-2345	110	32	was	be	AUX
dpc-2345	110	33	subjected	subject	VERB
dpc-2345	110	34	into	into	ADP
dpc-2345	110	35	the	the	DET
dpc-2345	110	36	column	column	NOUN
dpc-2345	110	37	.	.	PUNCT
dpc-2345	111	1	secondly	secondly	ADV
dpc-2345	111	2	,	,	PUNCT
dpc-2345	111	3	a	a	DET
dpc-2345	111	4	5	5	NUM
dpc-2345	111	5	µl	µl	NOUN
dpc-2345	111	6	/	/	SYM
dpc-2345	111	7	ml	ml	NOUN
dpc-2345	111	8	solution	solution	NOUN
dpc-2345	111	9	was	be	AUX
dpc-2345	111	10	made	make	VERB
dpc-2345	111	11	in	in	ADP
dpc-2345	111	12	0.5	0.5	NUM
dpc-2345	111	13	m	m	NOUN
dpc-2345	111	14	naoh	naoh	NOUN
dpc-2345	111	15	and	and	CCONJ
dpc-2345	111	16	incubated	incubate	VERB
dpc-2345	111	17	for	for	ADP
dpc-2345	111	18	12	12	NUM
dpc-2345	111	19	hours	hour	NOUN
dpc-2345	111	20	.	.	PUNCT
dpc-2345	112	1	after	after	ADP
dpc-2345	112	2	incubation	incubation	NOUN
dpc-2345	112	3	,	,	PUNCT
dpc-2345	112	4	the	the	DET
dpc-2345	112	5	solution	solution	NOUN
dpc-2345	112	6	was	be	AUX
dpc-2345	112	7	neutralized	neutralize	VERB
dpc-2345	112	8	by	by	ADP
dpc-2345	112	9	adding	add	VERB
dpc-2345	112	10	0.5	0.5	NUM
dpc-2345	112	11	m	m	NOUN
dpc-2345	112	12	hcl	hcl	PROPN
dpc-2345	112	13	,	,	PUNCT
dpc-2345	112	14	centrifuged	centrifuge	VERB
dpc-2345	112	15	;	;	PUNCT
dpc-2345	112	16	and	and	CCONJ
dpc-2345	112	17	20	20	NUM
dpc-2345	112	18	µl	µl	NOUN
dpc-2345	112	19	of	of	ADP
dpc-2345	112	20	this	this	DET
dpc-2345	112	21	solution	solution	NOUN
dpc-2345	112	22	was	be	AUX
dpc-2345	112	23	subjected	subject	VERB
dpc-2345	112	24	for	for	ADP
dpc-2345	112	25	hplc	hplc	NOUN
dpc-2345	112	26	analysis	analysis	NOUN
dpc-2345	112	27	.	.	PUNCT
dpc-2345	113	1	to	to	PART
dpc-2345	113	2	determine	determine	VERB
dpc-2345	113	3	the	the	DET
dpc-2345	113	4	stability	stability	NOUN
dpc-2345	113	5	of	of	ADP
dpc-2345	113	6	terbinafine	terbinafine	NOUN
dpc-2345	113	7	in	in	ADP
dpc-2345	113	8	the	the	DET
dpc-2345	113	9	digestion	digestion	NOUN
dpc-2345	113	10	procedure	procedure	NOUN
dpc-2345	113	11	,	,	PUNCT
dpc-2345	113	12	the	the	DET
dpc-2345	113	13	experiment	experiment	NOUN
dpc-2345	113	14	was	be	AUX
dpc-2345	113	15	repeated	repeat	VERB
dpc-2345	113	16	three	three	NUM
dpc-2345	113	17	times	time	NOUN
dpc-2345	113	18	to	to	PART
dpc-2345	113	19	ascertain	ascertain	VERB
dpc-2345	113	20	the	the	DET
dpc-2345	113	21	stability	stability	NOUN
dpc-2345	113	22	of	of	ADP
dpc-2345	113	23	terbinafine	terbinafine	NOUN
dpc-2345	113	24	in	in	ADP
dpc-2345	113	25	the	the	DET
dpc-2345	113	26	digestion	digestion	NOUN
dpc-2345	113	27	procedure	procedure	NOUN
dpc-2345	113	28	by	by	ADP
dpc-2345	113	29	taking	take	VERB
dpc-2345	113	30	into	into	ADP
dpc-2345	113	31	consideration	consideration	NOUN
dpc-2345	113	32	the	the	DET
dpc-2345	113	33	dilution	dilution	NOUN
dpc-2345	113	34	factor	factor	NOUN
dpc-2345	113	35	and	and	CCONJ
dpc-2345	113	36	the	the	DET
dpc-2345	113	37	areas	area	NOUN
dpc-2345	113	38	attained	attain	VERB
dpc-2345	113	39	after	after	ADP
dpc-2345	113	40	injection	injection	NOUN
dpc-2345	113	41	of	of	ADP
dpc-2345	113	42	aqueous	aqueous	ADJ
dpc-2345	113	43	and	and	CCONJ
dpc-2345	113	44	basic	basic	ADJ
dpc-2345	113	45	solutions	solution	NOUN
dpc-2345	113	46	.	.	PUNCT
dpc-2345	114	1	preparation	preparation	NOUN
dpc-2345	114	2	of	of	ADP
dpc-2345	114	3	the	the	DET
dpc-2345	114	4	calibrators	calibrator	NOUN
dpc-2345	114	5	in	in	ADP
dpc-2345	114	6	0.5	0.5	NUM
dpc-2345	114	7	m	m	NOUN
dpc-2345	114	8	naoh	naoh	NOUN
dpc-2345	114	9	,	,	PUNCT
dpc-2345	114	10	five	five	NUM
dpc-2345	114	11	calibrators	calibrator	NOUN
dpc-2345	114	12	of	of	ADP
dpc-2345	114	13	different	different	ADJ
dpc-2345	114	14	concentrations	concentration	NOUN
dpc-2345	114	15	of	of	ADP
dpc-2345	114	16	5	5	NUM
dpc-2345	114	17	,	,	PUNCT
dpc-2345	114	18	7.5	7.5	NUM
dpc-2345	114	19	,	,	PUNCT
dpc-2345	114	20	10	10	NUM
dpc-2345	114	21	,	,	PUNCT
dpc-2345	114	22	12.5	12.5	NUM
dpc-2345	114	23	,	,	PUNCT
dpc-2345	114	24	and	and	CCONJ
dpc-2345	114	25	15	15	NUM
dpc-2345	114	26	µg	µg	NOUN
dpc-2345	114	27	/	/	SYM
dpc-2345	114	28	ml	ml	NOUN
dpc-2345	114	29	were	be	AUX
dpc-2345	114	30	prepared	prepare	VERB
dpc-2345	114	31	from	from	ADP
dpc-2345	114	32	1mg	1mg	PROPN
dpc-2345	114	33	/	/	SYM
dpc-2345	114	34	ml	ml	NOUN
dpc-2345	114	35	stock	stock	NOUN
dpc-2345	114	36	solution	solution	NOUN
dpc-2345	114	37	of	of	ADP
dpc-2345	114	38	terbinafine	terbinafine	NOUN
dpc-2345	114	39	.	.	PUNCT
dpc-2345	115	1	for	for	ADP
dpc-2345	115	2	hplc	hplc	NOUN
dpc-2345	115	3	analysis	analysis	NOUN
dpc-2345	115	4	of	of	ADP
dpc-2345	115	5	calibrators	calibrator	NOUN
dpc-2345	115	6	,	,	PUNCT
dpc-2345	115	7	the	the	DET
dpc-2345	115	8	aforementioned	aforementioned	ADJ
dpc-2345	115	9	procedure	procedure	NOUN
dpc-2345	115	10	was	be	AUX
dpc-2345	115	11	employed	employ	VERB
dpc-2345	115	12	.	.	PUNCT
dpc-2345	116	1	and	and	CCONJ
dpc-2345	116	2	effective	effective	ADJ
dpc-2345	116	3	permeation	permeation	NOUN
dpc-2345	116	4	enhancers	enhancer	NOUN
dpc-2345	116	5	from	from	ADP
dpc-2345	116	6	natural	natural	ADJ
dpc-2345	116	7	sources	source	NOUN
dpc-2345	116	8	.	.	PUNCT
dpc-2345	117	1	in	in	ADP
dpc-2345	117	2	particular	particular	ADJ
dpc-2345	117	3	,	,	PUNCT
dpc-2345	117	4	terpenes	terpene	NOUN
dpc-2345	117	5	have	have	AUX
dpc-2345	117	6	gained	gain	VERB
dpc-2345	117	7	significant	significant	ADJ
dpc-2345	117	8	interest	interest	NOUN
dpc-2345	117	9	and	and	CCONJ
dpc-2345	117	10	are	be	AUX
dpc-2345	117	11	considered	consider	VERB
dpc-2345	117	12	clinically	clinically	ADV
dpc-2345	117	13	acceptable	acceptable	ADJ
dpc-2345	117	14	permeation	permeation	NOUN
dpc-2345	117	15	enhancers	enhancer	NOUN
dpc-2345	117	16	[	[	X
dpc-2345	117	17	21	21	NUM
dpc-2345	117	18	]	]	PUNCT
dpc-2345	117	19	.	.	PUNCT
dpc-2345	118	1	these	these	DET
dpc-2345	118	2	promising	promising	ADJ
dpc-2345	118	3	candidates	candidate	NOUN
dpc-2345	118	4	are	be	AUX
dpc-2345	118	5	considered	consider	VERB
dpc-2345	118	6	effective	effective	ADJ
dpc-2345	118	7	and	and	CCONJ
dpc-2345	118	8	constitute	constitute	VERB
dpc-2345	118	9	a	a	DET
dpc-2345	118	10	very	very	ADV
dpc-2345	118	11	safe	safe	ADJ
dpc-2345	118	12	class	class	NOUN
dpc-2345	118	13	of	of	ADP
dpc-2345	118	14	permeation	permeation	NOUN
dpc-2345	118	15	enhancers	enhancer	NOUN
dpc-2345	118	16	acquired	acquire	VERB
dpc-2345	118	17	from	from	ADP
dpc-2345	118	18	natural	natural	ADJ
dpc-2345	118	19	sources	source	NOUN
dpc-2345	118	20	.	.	PUNCT
dpc-2345	119	1	furthermore	furthermore	ADV
dpc-2345	119	2	,	,	PUNCT
dpc-2345	119	3	a	a	DET
dpc-2345	119	4	good	good	ADJ
dpc-2345	119	5	number	number	NOUN
dpc-2345	119	6	of	of	ADP
dpc-2345	119	7	terpenes	terpene	NOUN
dpc-2345	119	8	is	be	AUX
dpc-2345	119	9	incorporated	incorporate	VERB
dpc-2345	119	10	in	in	ADP
dpc-2345	119	11	the	the	DET
dpc-2345	119	12	list	list	NOUN
dpc-2345	119	13	of	of	ADP
dpc-2345	119	14	generally	generally	ADV
dpc-2345	119	15	recognized	recognize	VERB
dpc-2345	119	16	as	as	ADP
dpc-2345	119	17	safe	safe	ADJ
dpc-2345	119	18	(	(	PUNCT
dpc-2345	119	19	gras	gras	PROPN
dpc-2345	119	20	)	)	PUNCT
dpc-2345	119	21	classified	classify	VERB
dpc-2345	119	22	by	by	ADP
dpc-2345	119	23	the	the	DET
dpc-2345	119	24	us	us	PROPN
dpc-2345	119	25	fda	fda	PROPN
dpc-2345	120	1	[	[	X
dpc-2345	120	2	21	21	NUM
dpc-2345	120	3	]	]	PUNCT
dpc-2345	120	4	.	.	PUNCT
dpc-2345	121	1	the	the	DET
dpc-2345	121	2	penetration	penetration	NOUN
dpc-2345	121	3	enhancement	enhancement	NOUN
dpc-2345	121	4	ability	ability	NOUN
dpc-2345	121	5	of	of	ADP
dpc-2345	121	6	terpenes	terpene	NOUN
dpc-2345	121	7	for	for	ADP
dpc-2345	121	8	hydrophobic	hydrophobic	NOUN
dpc-2345	121	9	and	and	CCONJ
dpc-2345	121	10	hydrophilic	hydrophilic	ADJ
dpc-2345	121	11	drugs	drug	NOUN
dpc-2345	121	12	are	be	AUX
dpc-2345	121	13	ascribed	ascribe	VERB
dpc-2345	121	14	to	to	ADP
dpc-2345	121	15	their	their	PRON
dpc-2345	121	16	chemical	chemical	NOUN
dpc-2345	121	17	structure	structure	NOUN
dpc-2345	121	18	in	in	ADP
dpc-2345	121	19	addition	addition	NOUN
dpc-2345	121	20	to	to	ADP
dpc-2345	121	21	the	the	DET
dpc-2345	121	22	physicochemical	physicochemical	ADJ
dpc-2345	121	23	properties	property	NOUN
dpc-2345	121	24	,	,	PUNCT
dpc-2345	121	25	including	include	VERB
dpc-2345	121	26	size	size	NOUN
dpc-2345	121	27	and	and	CCONJ
dpc-2345	121	28	chirality	chirality	NOUN
dpc-2345	121	29	,	,	PUNCT
dpc-2345	121	30	degree	degree	NOUN
dpc-2345	121	31	of	of	ADP
dpc-2345	121	32	unsaturation	unsaturation	NOUN
dpc-2345	121	33	,	,	PUNCT
dpc-2345	121	34	lipophilicity	lipophilicity	PROPN
dpc-2345	121	35	,	,	PUNCT
dpc-2345	121	36	the	the	DET
dpc-2345	121	37	energy	energy	NOUN
dpc-2345	121	38	of	of	ADP
dpc-2345	121	39	vaporization	vaporization	NOUN
dpc-2345	121	40	,	,	PUNCT
dpc-2345	121	41	and	and	CCONJ
dpc-2345	121	42	boiling	boiling	NOUN
dpc-2345	121	43	point	point	NOUN
dpc-2345	121	44	[	[	X
dpc-2345	121	45	21	21	NUM
dpc-2345	121	46	]	]	PUNCT
dpc-2345	121	47	.	.	PUNCT
dpc-2345	122	1	in	in	ADP
dpc-2345	122	2	the	the	DET
dpc-2345	122	3	past	past	ADJ
dpc-2345	122	4	decades	decade	NOUN
dpc-2345	122	5	,	,	PUNCT
dpc-2345	122	6	several	several	ADJ
dpc-2345	122	7	findings	finding	NOUN
dpc-2345	122	8	have	have	AUX
dpc-2345	122	9	shown	show	VERB
dpc-2345	122	10	that	that	SCONJ
dpc-2345	122	11	in	in	ADP
dpc-2345	122	12	vitro	vitro	X
dpc-2345	122	13	transungual	transungual	ADJ
dpc-2345	122	14	studies	study	NOUN
dpc-2345	122	15	are	be	AUX
dpc-2345	122	16	used	use	VERB
dpc-2345	122	17	to	to	PART
dpc-2345	122	18	simulate	simulate	VERB
dpc-2345	122	19	and	and	CCONJ
dpc-2345	122	20	characterize	characterize	VERB
dpc-2345	122	21	the	the	DET
dpc-2345	122	22	in	in	ADP
dpc-2345	122	23	vivo	vivo	ADJ
dpc-2345	122	24	nail	nail	NOUN
dpc-2345	122	25	permeability	permeability	NOUN
dpc-2345	122	26	.	.	PUNCT
dpc-2345	123	1	permeation	permeation	NOUN
dpc-2345	123	2	studies	study	NOUN
dpc-2345	123	3	using	use	VERB
dpc-2345	123	4	franz	franz	NOUN
dpc-2345	123	5	diffusion	diffusion	NOUN
dpc-2345	123	6	cells	cell	NOUN
dpc-2345	123	7	,	,	PUNCT
dpc-2345	123	8	measurement	measurement	NOUN
dpc-2345	123	9	of	of	ADP
dpc-2345	123	10	nail	nail	NOUN
dpc-2345	123	11	swelling	swelling	NOUN
dpc-2345	123	12	and	and	CCONJ
dpc-2345	123	13	drug	drug	NOUN
dpc-2345	123	14	uptake	uptake	NOUN
dpc-2345	123	15	by	by	ADP
dpc-2345	123	16	nails	nail	NOUN
dpc-2345	123	17	after	after	ADP
dpc-2345	123	18	soaking	soak	VERB
dpc-2345	123	19	nail	nail	NOUN
dpc-2345	123	20	clippings	clipping	NOUN
dpc-2345	123	21	in	in	ADP
dpc-2345	123	22	drug	drug	NOUN
dpc-2345	123	23	solutions	solution	NOUN
dpc-2345	123	24	are	be	AUX
dpc-2345	123	25	often	often	ADV
dpc-2345	123	26	used	use	VERB
dpc-2345	123	27	.	.	PUNCT
dpc-2345	124	1	though	though	ADV
dpc-2345	124	2	,	,	PUNCT
dpc-2345	124	3	in	in	ADP
dpc-2345	124	4	the	the	DET
dpc-2345	124	5	recent	recent	ADJ
dpc-2345	124	6	works	work	NOUN
dpc-2345	124	7	,	,	PUNCT
dpc-2345	124	8	it	it	PRON
dpc-2345	124	9	was	be	AUX
dpc-2345	124	10	found	find	VERB
dpc-2345	124	11	that	that	SCONJ
dpc-2345	124	12	keratin	keratin	NOUN
dpc-2345	124	13	guards	guard	NOUN
dpc-2345	124	14	the	the	DET
dpc-2345	124	15	analyte	analyte	NOUN
dpc-2345	124	16	present	present	ADJ
dpc-2345	124	17	in	in	ADP
dpc-2345	124	18	the	the	DET
dpc-2345	124	19	nail	nail	NOUN
dpc-2345	124	20	matrix	matrix	NOUN
dpc-2345	124	21	and	and	CCONJ
dpc-2345	124	22	hampers	hamper	VERB
dpc-2345	124	23	the	the	DET
dpc-2345	124	24	availability	availability	NOUN
dpc-2345	124	25	of	of	ADP
dpc-2345	124	26	solvent	solvent	NOUN
dpc-2345	124	27	and	and	CCONJ
dpc-2345	124	28	other	other	ADJ
dpc-2345	124	29	reagents	reagent	NOUN
dpc-2345	124	30	[	[	X
dpc-2345	124	31	18	18	NUM
dpc-2345	124	32	]	]	PUNCT
dpc-2345	124	33	.	.	PUNCT
dpc-2345	125	1	hence	hence	ADV
dpc-2345	125	2	,	,	PUNCT
dpc-2345	125	3	a	a	DET
dpc-2345	125	4	digestion	digestion	NOUN
dpc-2345	125	5	step	step	NOUN
dpc-2345	125	6	was	be	AUX
dpc-2345	125	7	required	require	VERB
dpc-2345	125	8	to	to	PART
dpc-2345	125	9	assess	assess	VERB
dpc-2345	125	10	the	the	DET
dpc-2345	125	11	terbinafine	terbinafine	ADJ
dpc-2345	125	12	concentration	concentration	NOUN
dpc-2345	125	13	in	in	ADP
dpc-2345	125	14	the	the	DET
dpc-2345	125	15	nail	nail	NOUN
dpc-2345	125	16	before	before	ADP
dpc-2345	125	17	analysis	analysis	NOUN
dpc-2345	125	18	.	.	PUNCT
dpc-2345	126	1	in	in	ADP
dpc-2345	126	2	the	the	DET
dpc-2345	126	3	present	present	ADJ
dpc-2345	126	4	study	study	NOUN
dpc-2345	126	5	,	,	PUNCT
dpc-2345	126	6	effect	effect	NOUN
dpc-2345	126	7	of	of	ADP
dpc-2345	126	8	different	different	ADJ
dpc-2345	126	9	terpenes	terpene	NOUN
dpc-2345	126	10	was	be	AUX
dpc-2345	126	11	investigated	investigate	VERB
dpc-2345	126	12	on	on	ADP
dpc-2345	126	13	the	the	DET
dpc-2345	126	14	transungual	transungual	ADJ
dpc-2345	126	15	permeation	permeation	NOUN
dpc-2345	126	16	of	of	ADP
dpc-2345	126	17	terbinafine	terbinafine	NOUN
dpc-2345	126	18	and	and	CCONJ
dpc-2345	126	19	these	these	PRON
dpc-2345	126	20	were	be	AUX
dpc-2345	126	21	found	find	VERB
dpc-2345	126	22	to	to	PART
dpc-2345	126	23	increase	increase	VERB
dpc-2345	126	24	its	its	PRON
dpc-2345	126	25	permeation	permeation	NOUN
dpc-2345	126	26	in	in	ADP
dpc-2345	126	27	following	follow	VERB
dpc-2345	126	28	order	order	NOUN
dpc-2345	126	29	:	:	PUNCT
dpc-2345	126	30	linalool	linalool	NOUN
dpc-2345	126	31	>	>	X
dpc-2345	126	32	rose	rise	VERB
dpc-2345	126	33	oxide	oxide	NOUN
dpc-2345	126	34	>	>	X
dpc-2345	126	35	3	3	NUM
dpc-2345	126	36	-	-	PUNCT
dpc-2345	126	37	methyl-2	methyl-2	NOUN
dpc-2345	126	38	-	-	PUNCT
dpc-2345	126	39	butene-1	butene-1	NOUN
dpc-2345	126	40	-	-	PUNCT
dpc-2345	126	41	ol	ol	NOUN
dpc-2345	126	42	>	>	X
dpc-2345	126	43	safranal	safranal	ADJ
dpc-2345	126	44	>	>	X
dpc-2345	126	45	limonene	limonene	PROPN
dpc-2345	126	46	>	>	X
dpc-2345	126	47	lavandulol	lavandulol	PROPN
dpc-2345	126	48	acetate	acetate	NOUN
dpc-2345	126	49	.	.	PUNCT
dpc-2345	127	1	thus	thus	ADV
dpc-2345	127	2	,	,	PUNCT
dpc-2345	127	3	linalool	linalool	NOUN
dpc-2345	127	4	was	be	AUX
dpc-2345	127	5	found	find	VERB
dpc-2345	127	6	to	to	PART
dpc-2345	127	7	be	be	AUX
dpc-2345	127	8	the	the	DET
dpc-2345	127	9	most	most	ADV
dpc-2345	127	10	effective	effective	ADJ
dpc-2345	127	11	penetration	penetration	NOUN
dpc-2345	127	12	enhancer	enhancer	NOUN
dpc-2345	127	13	for	for	ADP
dpc-2345	127	14	the	the	DET
dpc-2345	127	15	transungual	transungual	ADJ
dpc-2345	127	16	delivery	delivery	NOUN
dpc-2345	127	17	of	of	ADP
dpc-2345	127	18	terbinafine	terbinafine	NOUN
dpc-2345	127	19	.	.	PUNCT
dpc-2345	128	1	difference	difference	NOUN
dpc-2345	128	2	between	between	ADP
dpc-2345	128	3	the	the	DET
dpc-2345	128	4	control	control	NOUN
dpc-2345	128	5	group	group	NOUN
dpc-2345	128	6	and	and	CCONJ
dpc-2345	128	7	the	the	DET
dpc-2345	128	8	lavandulol	lavandulol	NOUN
dpc-2345	128	9	,	,	PUNCT
dpc-2345	128	10	safranal	safranal	ADJ
dpc-2345	128	11	,	,	PUNCT
dpc-2345	128	12	rose	rise	VERB
dpc-2345	128	13	oxide	oxide	NOUN
dpc-2345	128	14	,	,	PUNCT
dpc-2345	128	15	limonene	limonene	NOUN
dpc-2345	128	16	,	,	PUNCT
dpc-2345	128	17	3	3	NUM
dpc-2345	128	18	-	-	PUNCT
dpc-2345	128	19	methyl-2	methyl-2	NOUN
dpc-2345	128	20	-	-	PUNCT
dpc-2345	128	21	butene-1	butene-1	NOUN
dpc-2345	128	22	-	-	PUNCT
dpc-2345	128	23	ol	ol	NOUN
dpc-2345	128	24	,	,	PUNCT
dpc-2345	128	25	and	and	CCONJ
dpc-2345	128	26	linalool	linalool	NOUN
dpc-2345	128	27	groups	group	NOUN
dpc-2345	128	28	.	.	PUNCT
dpc-2345	129	1	the	the	DET
dpc-2345	129	2	above	above	ADJ
dpc-2345	129	3	results	result	NOUN
dpc-2345	129	4	reveal	reveal	VERB
dpc-2345	129	5	that	that	SCONJ
dpc-2345	129	6	terpenes	terpene	NOUN
dpc-2345	129	7	increase	increase	VERB
dpc-2345	129	8	transungual	transungual	ADJ
dpc-2345	129	9	penetration	penetration	NOUN
dpc-2345	129	10	of	of	ADP
dpc-2345	129	11	terbinafine	terbinafine	NOUN
dpc-2345	129	12	in	in	ADP
dpc-2345	129	13	the	the	DET
dpc-2345	129	14	following	follow	VERB
dpc-2345	129	15	order	order	NOUN
dpc-2345	129	16	:	:	PUNCT
dpc-2345	129	17	linalool	linalool	NOUN
dpc-2345	129	18	>	>	X
dpc-2345	129	19	rose	rise	VERB
dpc-2345	129	20	oxide	oxide	NOUN
dpc-2345	129	21	>	>	X
dpc-2345	129	22	3	3	NUM
dpc-2345	129	23	-	-	PUNCT
dpc-2345	129	24	methyl-2	methyl-2	NOUN
dpc-2345	129	25	-	-	PUNCT
dpc-2345	129	26	butene-1	butene-1	NOUN
dpc-2345	129	27	-	-	PUNCT
dpc-2345	129	28	ol	ol	NOUN
dpc-2345	129	29	>	>	X
dpc-2345	129	30	safranal	safranal	ADJ
dpc-2345	129	31	>	>	X
dpc-2345	129	32	limonene	limonene	PROPN
dpc-2345	129	33	>	>	X
dpc-2345	129	34	lavandulol	lavandulol	PROPN
dpc-2345	129	35	acetate	acetate	PROPN
dpc-2345	129	36	.	.	PUNCT
dpc-2345	130	1	conclusions	conclusion	NOUN
dpc-2345	130	2	topical	topical	ADJ
dpc-2345	130	3	therapy	therapy	NOUN
dpc-2345	130	4	is	be	AUX
dpc-2345	130	5	at	at	ADP
dpc-2345	130	6	the	the	DET
dpc-2345	130	7	forefront	forefront	NOUN
dpc-2345	130	8	for	for	ADP
dpc-2345	130	9	the	the	DET
dpc-2345	130	10	treatment	treatment	NOUN
dpc-2345	130	11	of	of	ADP
dpc-2345	130	12	many	many	ADJ
dpc-2345	130	13	disorders	disorder	NOUN
dpc-2345	130	14	of	of	ADP
dpc-2345	130	15	nail	nail	NOUN
dpc-2345	130	16	and	and	CCONJ
dpc-2345	130	17	skin	skin	NOUN
dpc-2345	130	18	due	due	ADP
dpc-2345	130	19	to	to	ADP
dpc-2345	130	20	higher	high	ADJ
dpc-2345	130	21	patient	patient	ADJ
dpc-2345	130	22	compliance	compliance	NOUN
dpc-2345	130	23	and	and	CCONJ
dpc-2345	130	24	lesser	less	ADJ
dpc-2345	130	25	side	side	NOUN
dpc-2345	130	26	effects	effect	NOUN
dpc-2345	130	27	accompanied	accompany	VERB
dpc-2345	130	28	with	with	ADP
dpc-2345	130	29	systemic	systemic	ADJ
dpc-2345	130	30	therapy	therapy	NOUN
dpc-2345	130	31	.	.	PUNCT
dpc-2345	131	1	howbeit	howbeit	PROPN
dpc-2345	131	2	,	,	PUNCT
dpc-2345	131	3	the	the	DET
dpc-2345	131	4	nail	nail	NOUN
dpc-2345	131	5	disorders	disorder	NOUN
dpc-2345	131	6	are	be	AUX
dpc-2345	131	7	frequently	frequently	ADV
dpc-2345	131	8	strenuous	strenuous	ADJ
dpc-2345	131	9	to	to	PART
dpc-2345	131	10	cure	cure	VERB
dpc-2345	131	11	and	and	CCONJ
dpc-2345	131	12	require	require	VERB
dpc-2345	131	13	long	long	ADJ
dpc-2345	131	14	term	term	NOUN
dpc-2345	131	15	therapy	therapy	NOUN
dpc-2345	131	16	.	.	PUNCT
dpc-2345	132	1	the	the	DET
dpc-2345	132	2	nail	nail	NOUN
dpc-2345	132	3	plate	plate	NOUN
dpc-2345	132	4	is	be	AUX
dpc-2345	132	5	an	an	DET
dpc-2345	132	6	aggregate	aggregate	NOUN
dpc-2345	132	7	of	of	ADP
dpc-2345	132	8	highly	highly	ADV
dpc-2345	132	9	dense	dense	ADJ
dpc-2345	132	10	keratinized	keratinized	ADJ
dpc-2345	132	11	tissue	tissue	NOUN
dpc-2345	132	12	which	which	PRON
dpc-2345	132	13	in	in	ADP
dpc-2345	132	14	turn	turn	NOUN
dpc-2345	132	15	gives	give	VERB
dpc-2345	132	16	low	low	ADJ
dpc-2345	132	17	permeability	permeability	NOUN
dpc-2345	132	18	to	to	ADP
dpc-2345	132	19	the	the	DET
dpc-2345	132	20	diffusing	diffuse	VERB
dpc-2345	132	21	substances	substance	NOUN
dpc-2345	132	22	[	[	X
dpc-2345	132	23	26	26	NUM
dpc-2345	132	24	]	]	PUNCT
dpc-2345	132	25	.	.	PUNCT
dpc-2345	133	1	a	a	DET
dpc-2345	133	2	number	number	NOUN
dpc-2345	133	3	of	of	ADP
dpc-2345	133	4	approaches	approach	NOUN
dpc-2345	133	5	have	have	AUX
dpc-2345	133	6	been	be	AUX
dpc-2345	133	7	shown	show	VERB
dpc-2345	133	8	to	to	PART
dpc-2345	133	9	be	be	AUX
dpc-2345	133	10	effective	effective	ADJ
dpc-2345	133	11	in	in	ADP
dpc-2345	133	12	enhancing	enhance	VERB
dpc-2345	133	13	transungual	transungual	ADJ
dpc-2345	133	14	permeation	permeation	NOUN
dpc-2345	133	15	such	such	ADJ
dpc-2345	133	16	as	as	ADP
dpc-2345	133	17	mechanical	mechanical	ADJ
dpc-2345	133	18	methods	method	NOUN
dpc-2345	133	19	(	(	PUNCT
dpc-2345	133	20	nail	nail	NOUN
dpc-2345	133	21	abrasion	abrasion	NOUN
dpc-2345	133	22	and	and	CCONJ
dpc-2345	133	23	nail	nail	NOUN
dpc-2345	133	24	avulsion	avulsion	NOUN
dpc-2345	133	25	)	)	PUNCT
dpc-2345	133	26	,	,	PUNCT
dpc-2345	133	27	physical	physical	ADJ
dpc-2345	133	28	techniques	technique	NOUN
dpc-2345	133	29	(	(	PUNCT
dpc-2345	133	30	u.v	u.v	PRON
dpc-2345	133	31	light	light	NOUN
dpc-2345	133	32	,	,	PUNCT
dpc-2345	133	33	carbon	carbon	NOUN
dpc-2345	133	34	dioxide	dioxide	NOUN
dpc-2345	133	35	laser	laser	NOUN
dpc-2345	133	36	,	,	PUNCT
dpc-2345	133	37	iontophoresis	iontophoresis	NOUN
dpc-2345	133	38	,	,	PUNCT
dpc-2345	133	39	occlusion	occlusion	NOUN
dpc-2345	133	40	and	and	CCONJ
dpc-2345	133	41	hydration	hydration	NOUN
dpc-2345	133	42	,	,	PUNCT
dpc-2345	133	43	sonophoresis	sonophoresis	NOUN
dpc-2345	133	44	,	,	PUNCT
dpc-2345	133	45	photodynamic	photodynamic	ADJ
dpc-2345	133	46	therapy	therapy	NOUN
dpc-2345	133	47	,	,	PUNCT
dpc-2345	133	48	electroporation	electroporation	NOUN
dpc-2345	133	49	and	and	CCONJ
dpc-2345	133	50	acid	acid	NOUN
dpc-2345	133	51	etching	etching	NOUN
dpc-2345	133	52	)	)	PUNCT
dpc-2345	133	53	or	or	CCONJ
dpc-2345	133	54	use	use	NOUN
dpc-2345	133	55	of	of	ADP
dpc-2345	133	56	chemical	chemical	ADJ
dpc-2345	133	57	penetration	penetration	NOUN
dpc-2345	133	58	enhancers	enhancer	NOUN
dpc-2345	133	59	(	(	PUNCT
dpc-2345	133	60	keratolytic	keratolytic	ADJ
dpc-2345	133	61	agents	agent	NOUN
dpc-2345	133	62	,	,	PUNCT
dpc-2345	133	63	water	water	NOUN
dpc-2345	133	64	,	,	PUNCT
dpc-2345	133	65	keratinolytic	keratinolytic	ADJ
dpc-2345	133	66	enzymes	enzyme	NOUN
dpc-2345	133	67	,	,	PUNCT
dpc-2345	133	68	urea	urea	NOUN
dpc-2345	133	69	,	,	PUNCT
dpc-2345	133	70	mercaptans	mercaptan	NOUN
dpc-2345	133	71	,	,	PUNCT
dpc-2345	133	72	sulfides	sulfide	NOUN
dpc-2345	133	73	and	and	CCONJ
dpc-2345	133	74	hydrogen	hydrogen	NOUN
dpc-2345	133	75	peroxides	peroxide	NOUN
dpc-2345	133	76	)	)	PUNCT
dpc-2345	134	1	[	[	X
dpc-2345	134	2	26	26	NUM
dpc-2345	134	3	]	]	PUNCT
dpc-2345	134	4	.	.	PUNCT
dpc-2345	135	1	literature	literature	NOUN
dpc-2345	135	2	and	and	CCONJ
dpc-2345	135	3	patent	patent	NOUN
dpc-2345	135	4	search	search	NOUN
dpc-2345	135	5	divulged	divulge	VERB
dpc-2345	135	6	that	that	SCONJ
dpc-2345	135	7	chemical	chemical	ADJ
dpc-2345	135	8	penetration	penetration	NOUN
dpc-2345	135	9	enhancers	enhancer	NOUN
dpc-2345	135	10	excel	excel	VERB
dpc-2345	135	11	over	over	ADP
dpc-2345	135	12	other	other	ADJ
dpc-2345	135	13	strategies	strategy	NOUN
dpc-2345	135	14	for	for	ADP
dpc-2345	135	15	the	the	DET
dpc-2345	135	16	transungual	transungual	ADJ
dpc-2345	135	17	delivery	delivery	NOUN
dpc-2345	135	18	of	of	ADP
dpc-2345	135	19	drugs	drug	NOUN
dpc-2345	135	20	.	.	PUNCT
dpc-2345	136	1	albeit	albeit	SCONJ
dpc-2345	136	2	the	the	DET
dpc-2345	136	3	concentration	concentration	NOUN
dpc-2345	136	4	required	require	VERB
dpc-2345	136	5	to	to	PART
dpc-2345	136	6	achieve	achieve	VERB
dpc-2345	136	7	useful	useful	ADJ
dpc-2345	136	8	levels	level	NOUN
dpc-2345	136	9	of	of	ADP
dpc-2345	136	10	permeation	permeation	NOUN
dpc-2345	136	11	enhancements	enhancement	NOUN
dpc-2345	136	12	may	may	AUX
dpc-2345	136	13	cause	cause	VERB
dpc-2345	136	14	irritancy	irritancy	NOUN
dpc-2345	136	15	at	at	ADP
dpc-2345	136	16	the	the	DET
dpc-2345	136	17	site	site	NOUN
dpc-2345	136	18	of	of	ADP
dpc-2345	136	19	application	application	NOUN
dpc-2345	136	20	[	[	X
dpc-2345	136	21	19,20	19,20	NOUN
dpc-2345	136	22	]	]	PUNCT
dpc-2345	136	23	.	.	PUNCT
dpc-2345	137	1	hence	hence	ADV
dpc-2345	137	2	,	,	PUNCT
dpc-2345	137	3	the	the	DET
dpc-2345	137	4	investigations	investigation	NOUN
dpc-2345	137	5	have	have	AUX
dpc-2345	137	6	been	be	AUX
dpc-2345	137	7	diverted	divert	VERB
dpc-2345	137	8	towards	towards	ADP
dpc-2345	137	9	searching	search	VERB
dpc-2345	137	10	safe	safe	ADJ
dpc-2345	137	11	table	table	NOUN
dpc-2345	137	12	2	2	NUM
dpc-2345	137	13	.	.	PUNCT
dpc-2345	137	14	concentration	concentration	NOUN
dpc-2345	137	15	of	of	ADP
dpc-2345	137	16	terbinafine	terbinafine	NOUN
dpc-2345	137	17	(	(	PUNCT
dpc-2345	137	18	µg	µg	ADV
dpc-2345	137	19	mg-1	mg-1	NOUN
dpc-2345	137	20	)	)	PUNCT
dpc-2345	137	21	found	find	VERB
dpc-2345	137	22	in	in	ADP
dpc-2345	137	23	nail	nail	NOUN
dpc-2345	137	24	samples	sample	NOUN
dpc-2345	137	25	from	from	ADP
dpc-2345	137	26	healthy	healthy	ADJ
dpc-2345	137	27	individuals	individual	NOUN
dpc-2345	137	28	and	and	CCONJ
dpc-2345	137	29	the	the	DET
dpc-2345	137	30	results	result	NOUN
dpc-2345	137	31	from	from	ADP
dpc-2345	137	32	statistical	statistical	ADJ
dpc-2345	137	33	analysis	analysis	NOUN
dpc-2345	137	34	.	.	PUNCT
dpc-2345	138	1	volunteers	volunteer	NOUN
dpc-2345	138	2	control	control	PROPN
dpc-2345	138	3	group	group	PROPN
dpc-2345	138	4	a	a	DET
dpc-2345	138	5	group	group	NOUN
dpc-2345	138	6	b	b	PROPN
dpc-2345	138	7	group	group	NOUN
dpc-2345	138	8	c	c	PROPN
dpc-2345	138	9	group	group	PROPN
dpc-2345	138	10	d	d	PROPN
dpc-2345	138	11	group	group	PROPN
dpc-2345	138	12	e	e	PROPN
dpc-2345	138	13	group	group	NOUN
dpc-2345	138	14	f	f	PROPN
dpc-2345	138	15	group	group	PROPN
dpc-2345	138	16	g	g	PROPN
dpc-2345	138	17	1	1	NUM
dpc-2345	138	18	3.445	3.445	NUM
dpc-2345	138	19	3.544	3.544	NUM
dpc-2345	138	20	3.608	3.608	NUM
dpc-2345	138	21	4.599	4.599	NUM
dpc-2345	138	22	3.579	3.579	NUM
dpc-2345	138	23	4.496	4.496	NUM
dpc-2345	138	24	4.785	4.785	NUM
dpc-2345	138	25	2	2	NUM
dpc-2345	138	26	3.345	3.345	NUM
dpc-2345	138	27	3.495	3.495	NUM
dpc-2345	138	28	3.492	3.492	NUM
dpc-2345	138	29	4.682	4.682	NUM
dpc-2345	138	30	3.526	3.526	NUM
dpc-2345	138	31	4.386	4.386	NUM
dpc-2345	138	32	4.742	4.742	NUM
dpc-2345	138	33	3	3	NUM
dpc-2345	138	34	3.125	3.125	NUM
dpc-2345	138	35	3.473	3.473	NUM
dpc-2345	138	36	3.571	3.571	NUM
dpc-2345	138	37	4.564	4.564	NUM
dpc-2345	138	38	3.605	3.605	NUM
dpc-2345	138	39	4.462	4.462	NUM
dpc-2345	138	40	4.721	4.721	NUM
dpc-2345	138	41	4	4	NUM
dpc-2345	138	42	3.320	3.320	NUM
dpc-2345	138	43	3.372	3.372	NUM
dpc-2345	138	44	3.774	3.774	NUM
dpc-2345	138	45	4.469	4.469	NUM
dpc-2345	138	46	3.502	3.502	NUM
dpc-2345	138	47	4.465	4.465	NUM
dpc-2345	138	48	4.746	4.746	NUM
dpc-2345	138	49	5	5	NUM
dpc-2345	138	50	3.395	3.395	NUM
dpc-2345	138	51	3.448	3.448	NUM
dpc-2345	138	52	3.546	3.546	NUM
dpc-2345	138	53	4.532	4.532	NUM
dpc-2345	138	54	3.578	3.578	NUM
dpc-2345	138	55	4.436	4.436	NUM
dpc-2345	138	56	4.796	4.796	NUM
dpc-2345	138	57	6	6	NUM
dpc-2345	138	58	3.142	3.142	NUM
dpc-2345	138	59	3.494	3.494	NUM
dpc-2345	138	60	3.596	3.596	NUM
dpc-2345	138	61	4.486	4.486	NUM
dpc-2345	138	62	3.527	3.527	NUM
dpc-2345	138	63	4.482	4.482	NUM
dpc-2345	138	64	4.746	4.746	NUM
dpc-2345	138	65	7	7	NUM
dpc-2345	138	66	3.365	3.365	NUM
dpc-2345	138	67	3.521	3.521	NUM
dpc-2345	138	68	3.419	3.419	NUM
dpc-2345	138	69	4.516	4.516	NUM
dpc-2345	138	70	3.553	3.553	NUM
dpc-2345	138	71	4.428	4.428	NUM
dpc-2345	138	72	4.771	4.771	NUM
dpc-2345	138	73	8	8	NUM
dpc-2345	138	74	3.094	3.094	NUM
dpc-2345	138	75	3.548	3.548	NUM
dpc-2345	138	76	3.549	3.549	NUM
dpc-2345	138	77	4.542	4.542	NUM
dpc-2345	138	78	3.581	3.581	NUM
dpc-2345	138	79	4.538	4.538	NUM
dpc-2345	138	80	4.708	4.708	NUM
dpc-2345	138	81	9	9	NUM
dpc-2345	138	82	3.325	3.325	NUM
dpc-2345	138	83	3.476	3.476	NUM
dpc-2345	138	84	3.773	3.773	NUM
dpc-2345	138	85	4.569	4.569	NUM
dpc-2345	138	86	3.542	3.542	NUM
dpc-2345	138	87	4.462	4.462	NUM
dpc-2345	138	88	4.727	4.727	NUM
dpc-2345	138	89	10	10	NUM
dpc-2345	138	90	3.239	3.239	NUM
dpc-2345	138	91	3.486	3.486	NUM
dpc-2345	138	92	3.685	3.685	NUM
dpc-2345	138	93	4.576	4.576	NUM
dpc-2345	138	94	3.515	3.515	NUM
dpc-2345	138	95	4.475	4.475	NUM
dpc-2345	138	96	4.739	4.739	NUM
dpc-2345	138	97	mean	mean	NOUN
dpc-2345	138	98	3.280	3.280	NUM
dpc-2345	138	99	3.486	3.486	NUM
dpc-2345	138	100	3.601	3.601	NUM
dpc-2345	138	101	4.554	4.554	NUM
dpc-2345	138	102	3.551	3.551	NUM
dpc-2345	138	103	4.463	4.463	NUM
dpc-2345	138	104	4.748	4.748	NUM
dpc-2345	138	105	sd	sd	ADP
dpc-2345	138	106	0.122	0.122	NUM
dpc-2345	138	107	0.051	0.051	NUM
dpc-2345	138	108	0.115	0.115	NUM
dpc-2345	138	109	0.061	0.061	NUM
dpc-2345	138	110	0.038	0.038	NUM
dpc-2345	138	111	0.041	0.041	NUM
dpc-2345	138	112	0.028	0.028	NUM
dpc-2345	138	113	normality	normality	NOUN
dpc-2345	138	114	test	test	NOUN
dpc-2345	138	115	passed	pass	VERB
dpc-2345	138	116	passed	pass	VERB
dpc-2345	138	117	passed	pass	VERB
dpc-2345	138	118	passed	pass	VERB
dpc-2345	138	119	passed	pass	VERB
dpc-2345	138	120	passed	pass	VERB
dpc-2345	138	121	p	p	NOUN
dpc-2345	138	122	value	value	NOUN
dpc-2345	138	123	0.437	0.437	NUM
dpc-2345	138	124	0.382	0.382	NUM
dpc-2345	138	125	0.921	0.921	NUM
dpc-2345	138	126	0.517	0.517	NUM
dpc-2345	138	127	0.665	0.665	NUM
dpc-2345	138	128	0.381	0.381	NUM
dpc-2345	138	129	a=	a=	ADJ
dpc-2345	138	130	terbinafine	terbinafine	NOUN
dpc-2345	138	131	:	:	PUNCT
dpc-2345	138	132	b	b	X
dpc-2345	138	133	=	=	PUNCT
dpc-2345	138	134	terbinafine	terbinafine	NOUN
dpc-2345	138	135	with	with	ADP
dpc-2345	138	136	lavandulol	lavandulol	PROPN
dpc-2345	138	137	acetate	acetate	NOUN
dpc-2345	138	138	;	;	PUNCT
dpc-2345	138	139	c	c	X
dpc-2345	138	140	=	=	PUNCT
dpc-2345	138	141	terbinafine	terbinafine	NOUN
dpc-2345	138	142	with	with	ADP
dpc-2345	138	143	safranal	safranal	ADJ
dpc-2345	138	144	;	;	PUNCT
dpc-2345	138	145	d	d	X
dpc-2345	138	146	=	=	PUNCT
dpc-2345	138	147	terbinafine	terbinafine	NOUN
dpc-2345	138	148	with	with	ADP
dpc-2345	138	149	rose	rise	VERB
dpc-2345	138	150	oxide	oxide	NOUN
dpc-2345	138	151	;	;	PUNCT
dpc-2345	138	152	e	e	X
dpc-2345	138	153	=	=	PUNCT
dpc-2345	138	154	terbinafine	terbinafine	NOUN
dpc-2345	138	155	with	with	ADP
dpc-2345	138	156	limonene	limonene	NOUN
dpc-2345	138	157	;	;	PUNCT
dpc-2345	138	158	f	f	X
dpc-2345	138	159	=	=	PUNCT
dpc-2345	138	160	terbinafine	terbinafine	NOUN
dpc-2345	138	161	with	with	ADP
dpc-2345	138	162	3	3	NUM
dpc-2345	138	163	-	-	PUNCT
dpc-2345	138	164	methyl-2	methyl-2	NOUN
dpc-2345	138	165	-	-	PUNCT
dpc-2345	138	166	butene-1	butene-1	NOUN
dpc-2345	138	167	-	-	PUNCT
dpc-2345	138	168	ol	ol	NOUN
dpc-2345	138	169	;	;	PUNCT
dpc-2345	138	170	g	g	NOUN
dpc-2345	138	171	=	=	PUNCT
dpc-2345	138	172	terbinafine	terbinafine	NOUN
dpc-2345	138	173	with	with	ADP
dpc-2345	138	174	linalool	linalool	NOUN
dpc-2345	138	175	.	.	PUNCT
dpc-2345	139	1	6	6	NUM
dpc-2345	139	2	review	review	NOUN
dpc-2345	139	3	|	|	ADV
dpc-2345	139	4	dermatol	dermatol	ADJ
dpc-2345	139	5	pract	pract	NOUN
dpc-2345	139	6	concept	concept	NOUN
dpc-2345	139	7	.	.	PUNCT
dpc-2345	140	1	2022;12(4):e2022202	2022;12(4):e2022202	NUM
dpc-2345	140	2	0.110	0.110	NUM
dpc-2345	140	3	0.100	0.100	NUM
dpc-2345	140	4	0.090	0.090	NUM
dpc-2345	140	5	0.080	0.080	NUM
dpc-2345	140	6	0.070	0.070	NUM
dpc-2345	140	7	0.060	0.060	NUM
dpc-2345	140	8	a	a	DET
dpc-2345	140	9	/u	/u	ADV
dpc-2345	140	10	0.050	0.050	NUM
dpc-2345	140	11	0.040	0.040	NUM
dpc-2345	140	12	0.030	0.030	NUM
dpc-2345	140	13	0.020	0.020	NUM
dpc-2345	140	14	0.010	0.010	NUM
dpc-2345	140	15	0.000	0.000	NUM
dpc-2345	140	16	1.00	1.00	NUM
dpc-2345	140	17	2.00	2.00	NUM
dpc-2345	140	18	3.00	3.00	NUM
dpc-2345	140	19	4.00	4.00	NUM
dpc-2345	140	20	5.00	5.00	NUM
dpc-2345	140	21	minutes	minute	NOUN
dpc-2345	140	22	6.00	6.00	NUM
dpc-2345	140	23	7.00	7.00	NUM
dpc-2345	140	24	8.00	8.00	NUM
dpc-2345	140	25	9.00	9.00	NUM
dpc-2345	140	26	10.00	10.00	NUM
dpc-2345	140	27	b	b	NUM
dpc-2345	140	28	0.025	0.025	NUM
dpc-2345	140	29	0.020	0.020	NUM
dpc-2345	140	30	0.015	0.015	NUM
dpc-2345	140	31	a	a	DET
dpc-2345	140	32	/u	/u	ADV
dpc-2345	140	33	0.010	0.010	NUM
dpc-2345	140	34	0.005	0.005	NUM
dpc-2345	140	35	0.000	0.000	NUM
dpc-2345	140	36	1.00	1.00	NUM
dpc-2345	140	37	2.00	2.00	NUM
dpc-2345	140	38	3.00	3.00	NUM
dpc-2345	140	39	4.00	4.00	NUM
dpc-2345	140	40	5.00	5.00	NUM
dpc-2345	140	41	minutes	minute	NOUN
dpc-2345	140	42	6.00	6.00	NUM
dpc-2345	140	43	7.00	7.00	NUM
dpc-2345	140	44	8.00	8.00	NUM
dpc-2345	140	45	9.00	9.00	NUM
dpc-2345	140	46	10.00	10.00	NUM
dpc-2345	140	47	c	c	NOUN
dpc-2345	140	48	0.045	0.045	NUM
dpc-2345	140	49	0.040	0.040	NUM
dpc-2345	140	50	0.035	0.035	NUM
dpc-2345	140	51	0.030	0.030	NUM
dpc-2345	140	52	0.025	0.025	NUM
dpc-2345	140	53	a	a	DET
dpc-2345	140	54	/u	/u	ADV
dpc-2345	140	55	0.020	0.020	NUM
dpc-2345	140	56	0.015	0.015	NUM
dpc-2345	140	57	0.010	0.010	NUM
dpc-2345	140	58	0.005	0.005	NUM
dpc-2345	140	59	0.000	0.000	NUM
dpc-2345	140	60	1.00	1.00	NUM
dpc-2345	140	61	2.00	2.00	NUM
dpc-2345	140	62	3.00	3.00	NUM
dpc-2345	140	63	4.00	4.00	NUM
dpc-2345	140	64	5.00	5.00	NUM
dpc-2345	140	65	minutes	minute	NOUN
dpc-2345	140	66	6.00	6.00	NUM
dpc-2345	140	67	7.00	7.00	NUM
dpc-2345	140	68	8.00	8.00	NUM
dpc-2345	140	69	9.00	9.00	NUM
dpc-2345	140	70	10.00	10.00	NUM
dpc-2345	140	71	a	a	DET
dpc-2345	140	72	figure	figure	NOUN
dpc-2345	140	73	1	1	NUM
dpc-2345	140	74	.	.	PUNCT
dpc-2345	141	1	(	(	PUNCT
dpc-2345	141	2	a	a	X
dpc-2345	141	3	)	)	PUNCT
dpc-2345	141	4	hplc	hplc	NOUN
dpc-2345	141	5	chromatogram	chromatogram	NOUN
dpc-2345	141	6	of	of	ADP
dpc-2345	141	7	blank	blank	NOUN
dpc-2345	141	8	.	.	PUNCT
dpc-2345	142	1	(	(	PUNCT
dpc-2345	142	2	b	b	X
dpc-2345	142	3	)	)	PUNCT
dpc-2345	142	4	hplc	hplc	NOUN
dpc-2345	142	5	chromatogram	chromatogram	PROPN
dpc-2345	142	6	of	of	ADP
dpc-2345	142	7	standard	standard	ADJ
dpc-2345	142	8	terbinafine	terbinafine	NOUN
dpc-2345	142	9	.	.	PUNCT
dpc-2345	143	1	(	(	PUNCT
dpc-2345	143	2	c	c	X
dpc-2345	143	3	)	)	PUNCT
dpc-2345	143	4	hplc	hplc	NOUN
dpc-2345	143	5	chromatogram	chromatogram	PROPN
dpc-2345	143	6	of	of	ADP
dpc-2345	143	7	sample	sample	NOUN
dpc-2345	143	8	terbinafine	terbinafine	NOUN
dpc-2345	143	9	.	.	PUNCT
dpc-2345	144	1	review	review	VERB
dpc-2345	144	2	|	|	ADV
dpc-2345	144	3	dermatol	dermatol	ADJ
dpc-2345	144	4	pract	pract	NOUN
dpc-2345	144	5	concept	concept	NOUN
dpc-2345	144	6	.	.	PUNCT
dpc-2345	145	1	2022;12(4):e2022202	2022;12(4):e2022202	NUM
dpc-2345	145	2	7	7	NUM
dpc-2345	145	3	13	13	NUM
dpc-2345	145	4	.	.	PUNCT
dpc-2345	146	1	gupta	gupta	PROPN
dpc-2345	146	2	ak	ak	PROPN
dpc-2345	146	3	,	,	PUNCT
dpc-2345	146	4	scher	scher	PROPN
dpc-2345	146	5	rk	rk	PROPN
dpc-2345	146	6	.	.	PUNCT
dpc-2345	146	7	oral	oral	ADJ
dpc-2345	146	8	antifungal	antifungal	ADJ
dpc-2345	146	9	agents	agent	NOUN
dpc-2345	146	10	for	for	ADP
dpc-2345	146	11	onychomycosis	onychomycosis	NOUN
dpc-2345	146	12	.	.	PUNCT
dpc-2345	147	1	lancet	lancet	NOUN
dpc-2345	147	2	.	.	PUNCT
dpc-2345	148	1	1998;351(9102):541	1998;351(9102):541	NUM
dpc-2345	148	2	-	-	SYM
dpc-2345	148	3	542	542	NUM
dpc-2345	148	4	.	.	PUNCT
dpc-2345	149	1	doi	doi	NOUN
dpc-2345	149	2	:	:	PUNCT
dpc-2345	149	3	10.1016	10.1016	NUM
dpc-2345	149	4	/	/	SYM
dpc-2345	149	5	s0140	s0140	ADJ
dpc-2345	149	6	-6736(05)78552	-6736(05)78552	NOUN
dpc-2345	149	7	-	-	PUNCT
dpc-2345	149	8	4	4	NUM
dpc-2345	149	9	.	.	PUNCT
dpc-2345	150	1	pmid	pmid	NOUN
dpc-2345	150	2	:	:	PUNCT
dpc-2345	150	3	9492770	9492770	NUM
dpc-2345	150	4	.	.	PUNCT
dpc-2345	151	1	14	14	NUM
dpc-2345	151	2	.	.	PUNCT
dpc-2345	151	3	gupta	gupta	PROPN
dpc-2345	151	4	ak	ak	PROPN
dpc-2345	151	5	,	,	PUNCT
dpc-2345	151	6	simpson	simpson	PROPN
dpc-2345	151	7	fc	fc	PROPN
dpc-2345	151	8	.	.	PUNCT
dpc-2345	151	9	routes	route	NOUN
dpc-2345	151	10	of	of	ADP
dpc-2345	151	11	drug	drug	NOUN
dpc-2345	151	12	delivery	delivery	NOUN
dpc-2345	151	13	into	into	ADP
dpc-2345	151	14	the	the	DET
dpc-2345	151	15	nail	nail	NOUN
dpc-2345	151	16	apparatus	apparatus	NOUN
dpc-2345	151	17	:	:	PUNCT
dpc-2345	151	18	implications	implication	NOUN
dpc-2345	151	19	for	for	ADP
dpc-2345	151	20	the	the	DET
dpc-2345	151	21	efficacy	efficacy	NOUN
dpc-2345	151	22	of	of	ADP
dpc-2345	151	23	topical	topical	ADJ
dpc-2345	151	24	nail	nail	NOUN
dpc-2345	151	25	solutions	solution	NOUN
dpc-2345	151	26	in	in	ADP
dpc-2345	151	27	onychomycosis	onychomycosis	NOUN
dpc-2345	151	28	.	.	PUNCT
dpc-2345	152	1	j	j	PROPN
dpc-2345	152	2	dermatolog	dermatolog	PROPN
dpc-2345	152	3	treat	treat	NOUN
dpc-2345	152	4	.	.	PUNCT
dpc-2345	153	1	2016	2016	NUM
dpc-2345	153	2	;	;	PUNCT
dpc-2345	153	3	27(1):2–4	27(1):2–4	NUM
dpc-2345	153	4	.	.	PUNCT
dpc-2345	154	1	doi	doi	NOUN
dpc-2345	154	2	:	:	PUNCT
dpc-2345	154	3	10.3109/09546634.2015.1034081	10.3109/09546634.2015.1034081	NUM
dpc-2345	154	4	.	.	PUNCT
dpc-2345	155	1	pmid	pmid	NOUN
dpc-2345	155	2	:	:	PUNCT
dpc-2345	155	3	25983025	25983025	NUM
dpc-2345	155	4	.	.	PUNCT
dpc-2345	156	1	15	15	NUM
dpc-2345	156	2	.	.	PUNCT
dpc-2345	156	3	bseiso	bseiso	PROPN
dpc-2345	156	4	ea	ea	PROPN
dpc-2345	156	5	,	,	PUNCT
dpc-2345	156	6	nasr	nasr	PROPN
dpc-2345	156	7	m	m	PROPN
dpc-2345	156	8	,	,	PUNCT
dpc-2345	156	9	sammour	sammour	PROPN
dpc-2345	156	10	oa	oa	INTJ
dpc-2345	156	11	,	,	PUNCT
dpc-2345	156	12	abd	abd	PROPN
dpc-2345	156	13	el	el	PROPN
dpc-2345	156	14	gawad	gawad	PROPN
dpc-2345	156	15	na	na	PROPN
dpc-2345	156	16	.	.	PROPN
dpc-2345	156	17	novel	novel	ADJ
dpc-2345	156	18	nail	nail	NOUN
dpc-2345	156	19	penetration	penetration	NOUN
dpc-2345	156	20	enhancer	enhancer	NOUN
dpc-2345	156	21	containing	contain	VERB
dpc-2345	156	22	vesicles	vesicle	NOUN
dpc-2345	156	23	“	"	PUNCT
dpc-2345	156	24	npevs	npevs	VERB
dpc-2345	156	25	”	"	PUNCT
dpc-2345	156	26	for	for	ADP
dpc-2345	156	27	treatment	treatment	NOUN
dpc-2345	156	28	of	of	ADP
dpc-2345	156	29	onychomycosis	onychomycosis	NOUN
dpc-2345	156	30	.	.	PUNCT
dpc-2345	157	1	drug	drug	NOUN
dpc-2345	157	2	deliv	deliv	NOUN
dpc-2345	157	3	.	.	PUNCT
dpc-2345	158	1	2016;23(8):2813	2016;23(8):2813	NUM
dpc-2345	158	2	-	-	SYM
dpc-2345	158	3	2819	2819	NUM
dpc-2345	158	4	.	.	PUNCT
dpc-2345	159	1	doi	doi	NOUN
dpc-2345	159	2	:	:	PUNCT
dpc-2345	159	3	10.3109/10717544.2015.1099059	10.3109/10717544.2015.1099059	NUM
dpc-2345	159	4	.	.	PUNCT
dpc-2345	160	1	pmid	pmid	NOUN
dpc-2345	160	2	:	:	PUNCT
dpc-2345	160	3	26447337	26447337	NUM
dpc-2345	160	4	.	.	PUNCT
dpc-2345	161	1	16	16	NUM
dpc-2345	161	2	.	.	PUNCT
dpc-2345	162	1	murdan	murdan	PROPN
dpc-2345	162	2	s.	s.	PROPN
dpc-2345	162	3	enhancing	enhance	VERB
dpc-2345	162	4	the	the	DET
dpc-2345	162	5	nail	nail	NOUN
dpc-2345	162	6	permeability	permeability	NOUN
dpc-2345	162	7	of	of	ADP
dpc-2345	162	8	topically	topically	ADV
dpc-2345	162	9	applied	apply	VERB
dpc-2345	162	10	drugs	drug	NOUN
dpc-2345	162	11	.	.	PUNCT
dpc-2345	163	1	expert	expert	NOUN
dpc-2345	163	2	opin	opin	NOUN
dpc-2345	163	3	drug	drug	NOUN
dpc-2345	163	4	deliv	deliv	NOUN
dpc-2345	163	5	.	.	PUNCT
dpc-2345	164	1	2008;5(11):1267	2008;5(11):1267	NUM
dpc-2345	164	2	-	-	SYM
dpc-2345	164	3	1282	1282	NUM
dpc-2345	164	4	.	.	PUNCT
dpc-2345	165	1	doi	doi	NOUN
dpc-2345	165	2	:	:	PUNCT
dpc-2345	165	3	10.1517/17425240802497218	10.1517/17425240802497218	NUM
dpc-2345	165	4	.	.	PUNCT
dpc-2345	166	1	pmid	pmid	NOUN
dpc-2345	166	2	:	:	PUNCT
dpc-2345	166	3	18976136	18976136	NUM
dpc-2345	166	4	.	.	PUNCT
dpc-2345	167	1	17	17	NUM
dpc-2345	167	2	.	.	PUNCT
dpc-2345	168	1	ahad	ahad	PROPN
dpc-2345	168	2	a	a	PROPN
dpc-2345	168	3	,	,	PUNCT
dpc-2345	168	4	aqil	aqil	PROPN
dpc-2345	168	5	m	m	PROPN
dpc-2345	168	6	,	,	PUNCT
dpc-2345	168	7	kohli	kohli	PROPN
dpc-2345	168	8	k	k	PROPN
dpc-2345	168	9	,	,	PUNCT
dpc-2345	168	10	chaudhary	chaudhary	PROPN
dpc-2345	168	11	h	h	PROPN
dpc-2345	168	12	,	,	PUNCT
dpc-2345	168	13	sultana	sultana	PROPN
dpc-2345	168	14	y	y	PROPN
dpc-2345	168	15	,	,	PUNCT
dpc-2345	168	16	mujeeb	mujeeb	PROPN
dpc-2345	168	17	m.	m.	PROPN
dpc-2345	168	18	chemical	chemical	PROPN
dpc-2345	168	19	penetration	penetration	NOUN
dpc-2345	168	20	enhancers	enhancer	NOUN
dpc-2345	168	21	:	:	PUNCT
dpc-2345	168	22	a	a	DET
dpc-2345	168	23	patent	patent	NOUN
dpc-2345	168	24	review	review	NOUN
dpc-2345	168	25	.	.	PUNCT
dpc-2345	169	1	expert	expert	NOUN
dpc-2345	169	2	opin	opin	NOUN
dpc-2345	169	3	ther	ther	ADV
dpc-2345	170	1	pat	pat	PROPN
dpc-2345	170	2	.	.	PROPN
dpc-2345	170	3	2009;19(7):969–988	2009;19(7):969–988	NUM
dpc-2345	170	4	.	.	PUNCT
dpc-2345	171	1	doi	doi	NOUN
dpc-2345	171	2	:	:	PUNCT
dpc-2345	171	3	10.1517/13543770902989983	10.1517/13543770902989983	NUM
dpc-2345	171	4	.	.	PUNCT
dpc-2345	172	1	pmid	pmid	NOUN
dpc-2345	172	2	:	:	PUNCT
dpc-2345	172	3	19552513	19552513	NUM
dpc-2345	172	4	.	.	PUNCT
dpc-2345	173	1	18	18	NUM
dpc-2345	173	2	.	.	X
dpc-2345	173	3	adin	adin	PROPN
dpc-2345	173	4	sn	sn	PROPN
dpc-2345	173	5	,	,	PUNCT
dpc-2345	173	6	gupta	gupta	PROPN
dpc-2345	173	7	i	i	PRON
dpc-2345	173	8	,	,	PUNCT
dpc-2345	173	9	ali	ali	PROPN
dpc-2345	173	10	a	a	PROPN
dpc-2345	173	11	,	,	PUNCT
dpc-2345	173	12	aqil	aqil	PROPN
dpc-2345	173	13	m	m	PROPN
dpc-2345	173	14	,	,	PUNCT
dpc-2345	173	15	mujeeb	mujeeb	PROPN
dpc-2345	173	16	m	m	PROPN
dpc-2345	173	17	,	,	PUNCT
dpc-2345	173	18	sultana	sultana	PROPN
dpc-2345	173	19	y.	y.	PROPN
dpc-2345	173	20	investigation	investigation	NOUN
dpc-2345	173	21	on	on	ADP
dpc-2345	173	22	utility	utility	NOUN
dpc-2345	173	23	of	of	ADP
dpc-2345	173	24	some	some	DET
dpc-2345	173	25	novel	novel	ADJ
dpc-2345	173	26	terpenes	terpene	NOUN
dpc-2345	173	27	on	on	ADP
dpc-2345	173	28	transungual	transungual	ADJ
dpc-2345	173	29	delivery	delivery	NOUN
dpc-2345	173	30	of	of	ADP
dpc-2345	173	31	fluconazole	fluconazole	NOUN
dpc-2345	173	32	for	for	ADP
dpc-2345	173	33	the	the	DET
dpc-2345	173	34	management	management	NOUN
dpc-2345	173	35	of	of	ADP
dpc-2345	173	36	onychomycosis	onychomycosis	NOUN
dpc-2345	173	37	.	.	PUNCT
dpc-2345	174	1	j	j	PROPN
dpc-2345	174	2	cosmet	cosmet	PROPN
dpc-2345	174	3	dermatol	dermatol	NOUN
dpc-2345	174	4	.	.	PUNCT
dpc-2345	175	1	2022;00:1	2022;00:1	NUM
dpc-2345	175	2	-	-	SYM
dpc-2345	175	3	8	8	NUM
dpc-2345	175	4	.	.	PUNCT
dpc-2345	176	1	doi	doi	NOUN
dpc-2345	176	2	:	:	PUNCT
dpc-2345	176	3	10.1111	10.1111	NUM
dpc-2345	176	4	/	/	SYM
dpc-2345	176	5	jocd.14978	jocd.14978	PROPN
dpc-2345	176	6	.	.	PROPN
dpc-2345	176	7	19	19	NUM
dpc-2345	176	8	.	.	PUNCT
dpc-2345	177	1	murthy	murthy	PROPN
dpc-2345	177	2	sn	sn	PROPN
dpc-2345	177	3	,	,	PUNCT
dpc-2345	177	4	maibach	maibach	PROPN
dpc-2345	177	5	hi	hi	INTJ
dpc-2345	177	6	.	.	PUNCT
dpc-2345	177	7	topical	topical	ADJ
dpc-2345	177	8	nail	nail	NOUN
dpc-2345	177	9	products	product	NOUN
dpc-2345	177	10	and	and	CCONJ
dpc-2345	177	11	ungual	ungual	ADJ
dpc-2345	177	12	drug	drug	NOUN
dpc-2345	177	13	delivery	delivery	NOUN
dpc-2345	177	14	.	.	PUNCT
dpc-2345	178	1	boca	boca	PROPN
dpc-2345	178	2	raton	raton	PROPN
dpc-2345	178	3	:	:	PUNCT
dpc-2345	178	4	c.r.c	c.r.c	ADJ
dpc-2345	178	5	.	.	PUNCT
dpc-2345	179	1	press	press	VERB
dpc-2345	179	2	2013:1	2013:1	NUM
dpc-2345	179	3	-	-	SYM
dpc-2345	179	4	282	282	NUM
dpc-2345	179	5	.	.	PUNCT
dpc-2345	180	1	doi:10.1201	doi:10.1201	VERB
dpc-2345	180	2	/b12896	/b12896	PUNCT
dpc-2345	180	3	.	.	PUNCT
dpc-2345	181	1	corpus	corpus	PROPN
dpc-2345	181	2	i	i	PROPN
dpc-2345	181	3	d	d	PROPN
dpc-2345	181	4	:	:	PUNCT
dpc-2345	181	5	81753602	81753602	NUM
dpc-2345	181	6	.	.	PUNCT
dpc-2345	182	1	20	20	NUM
dpc-2345	182	2	.	.	PUNCT
dpc-2345	183	1	ahad	ahad	PROPN
dpc-2345	183	2	a	a	PROPN
dpc-2345	183	3	,	,	PUNCT
dpc-2345	183	4	aqil	aqil	PROPN
dpc-2345	183	5	m	m	PROPN
dpc-2345	183	6	,	,	PUNCT
dpc-2345	183	7	kohli	kohli	PROPN
dpc-2345	183	8	k	k	PROPN
dpc-2345	183	9	,	,	PUNCT
dpc-2345	183	10	sultana	sultana	PROPN
dpc-2345	183	11	y	y	PROPN
dpc-2345	183	12	,	,	PUNCT
dpc-2345	183	13	mujeeb	mujeeb	PROPN
dpc-2345	183	14	m	m	PROPN
dpc-2345	183	15	,	,	PUNCT
dpc-2345	183	16	ali	ali	PROPN
dpc-2345	183	17	a.	a.	NOUN
dpc-2345	183	18	role	role	NOUN
dpc-2345	183	19	of	of	ADP
dpc-2345	183	20	novel	novel	ADJ
dpc-2345	183	21	terpenes	terpene	NOUN
dpc-2345	183	22	in	in	ADP
dpc-2345	183	23	transcutaneous	transcutaneous	ADJ
dpc-2345	183	24	permeation	permeation	NOUN
dpc-2345	183	25	of	of	ADP
dpc-2345	183	26	valsartan	valsartan	PROPN
dpc-2345	183	27	:	:	PUNCT
dpc-2345	183	28	effectiveness	effectiveness	NOUN
dpc-2345	183	29	and	and	CCONJ
dpc-2345	183	30	mechanism	mechanism	NOUN
dpc-2345	183	31	of	of	ADP
dpc-2345	183	32	action	action	NOUN
dpc-2345	183	33	.	.	PUNCT
dpc-2345	184	1	drug	drug	PROPN
dpc-2345	184	2	dev	dev	PROPN
dpc-2345	184	3	ind	ind	PROPN
dpc-2345	184	4	pharm	pharm	PROPN
dpc-2345	184	5	.	.	PUNCT
dpc-2345	185	1	2011;37(5):58396	2011;37(5):58396	NUM
dpc-2345	185	2	.	.	PUNCT
dpc-2345	186	1	doi	doi	NOUN
dpc-2345	186	2	:	:	PUNCT
dpc-2345	186	3	10.3109/03639045.2010.532219	10.3109/03639045.2010.532219	NUM
dpc-2345	186	4	.	.	PUNCT
dpc-2345	187	1	pmid	pmid	NOUN
dpc-2345	187	2	:	:	PUNCT
dpc-2345	187	3	21469947	21469947	NUM
dpc-2345	187	4	.	.	PUNCT
dpc-2345	188	1	21	21	NUM
dpc-2345	188	2	.	.	X
dpc-2345	188	3	suganthini	suganthini	PROPN
dpc-2345	188	4	k.	k.	PROPN
dpc-2345	188	5	terbinafine	terbinafine	PROPN
dpc-2345	188	6	:	:	PUNCT
dpc-2345	188	7	a	a	DET
dpc-2345	188	8	pharmacological	pharmacological	ADJ
dpc-2345	188	9	and	and	CCONJ
dpc-2345	188	10	clinical	clinical	ADJ
dpc-2345	188	11	review	review	NOUN
dpc-2345	188	12	.	.	PUNCT
dpc-2345	189	1	expert	expert	NOUN
dpc-2345	189	2	opin	opin	NOUN
dpc-2345	189	3	pharmacother	pharmacother	NOUN
dpc-2345	189	4	.	.	PUNCT
dpc-2345	190	1	2009;10(16):2723	2009;10(16):2723	NUM
dpc-2345	190	2	-	-	SYM
dpc-2345	190	3	2733	2733	NUM
dpc-2345	190	4	.	.	PUNCT
dpc-2345	191	1	doi	doi	NOUN
dpc-2345	191	2	:	:	PUNCT
dpc-2345	191	3	10.1517/14656560903307462	10.1517/14656560903307462	NUM
dpc-2345	191	4	.	.	PUNCT
dpc-2345	192	1	pmid	pmid	NOUN
dpc-2345	192	2	:	:	PUNCT
dpc-2345	192	3	19874252	19874252	NUM
dpc-2345	192	4	.	.	PUNCT
dpc-2345	193	1	22	22	NUM
dpc-2345	193	2	.	.	PUNCT
dpc-2345	193	3	khengar	khengar	PROPN
dpc-2345	193	4	rh	rh	PROPN
dpc-2345	193	5	,	,	PUNCT
dpc-2345	193	6	jones	jones	PROPN
dpc-2345	193	7	sa	sa	PROPN
dpc-2345	193	8	,	,	PUNCT
dpc-2345	193	9	turner	turner	PROPN
dpc-2345	193	10	rb	rb	PROPN
dpc-2345	193	11	,	,	PUNCT
dpc-2345	193	12	forbes	forbes	PROPN
dpc-2345	193	13	b	b	PROPN
dpc-2345	193	14	,	,	PUNCT
dpc-2345	193	15	brown	brown	ADJ
dpc-2345	193	16	mb	mb	NOUN
dpc-2345	193	17	.	.	PUNCT
dpc-2345	193	18	nail	nail	NOUN
dpc-2345	193	19	swelling	swell	VERB
dpc-2345	193	20	as	as	ADP
dpc-2345	193	21	a	a	DET
dpc-2345	193	22	pre	pre	ADJ
dpc-2345	193	23	-	-	ADJ
dpc-2345	193	24	formulation	formulation	ADJ
dpc-2345	193	25	screen	screen	NOUN
dpc-2345	193	26	for	for	ADP
dpc-2345	193	27	the	the	DET
dpc-2345	193	28	selection	selection	NOUN
dpc-2345	193	29	and	and	CCONJ
dpc-2345	193	30	optimisation	optimisation	NOUN
dpc-2345	193	31	of	of	ADP
dpc-2345	193	32	ungual	ungual	ADJ
dpc-2345	193	33	penetration	penetration	NOUN
dpc-2345	193	34	enhancers	enhancer	NOUN
dpc-2345	193	35	.	.	PUNCT
dpc-2345	194	1	pharm	pharm	NOUN
dpc-2345	194	2	res	re	NOUN
dpc-2345	194	3	.	.	PUNCT
dpc-2345	195	1	2007;24(12):2207–2212	2007;24(12):2207–2212	NUM
dpc-2345	195	2	.	.	PUNCT
dpc-2345	196	1	doi	doi	NOUN
dpc-2345	196	2	:	:	PUNCT
dpc-2345	196	3	10.1007	10.1007	NUM
dpc-2345	196	4	/	/	SYM
dpc-2345	196	5	s11095	s11095	NOUN
dpc-2345	196	6	-	-	PUNCT
dpc-2345	196	7	007	007	NUM
dpc-2345	196	8	-	-	PUNCT
dpc-2345	196	9	9368	9368	NUM
dpc-2345	196	10	-	-	PUNCT
dpc-2345	196	11	3	3	NUM
dpc-2345	196	12	.	.	PUNCT
dpc-2345	197	1	pmid	pmid	NOUN
dpc-2345	197	2	:	:	PUNCT
dpc-2345	197	3	17665289	17665289	NUM
dpc-2345	197	4	.	.	PUNCT
dpc-2345	198	1	23	23	NUM
dpc-2345	198	2	.	.	PUNCT
dpc-2345	199	1	walters	walters	PROPN
dpc-2345	199	2	ka	ka	PROPN
dpc-2345	199	3	,	,	PUNCT
dpc-2345	199	4	abdalghafor	abdalghafor	ADP
dpc-2345	199	5	hm	hm	INTJ
dpc-2345	199	6	,	,	PUNCT
dpc-2345	199	7	lane	lane	VERB
dpc-2345	199	8	me	i	PRON
dpc-2345	199	9	.	.	PUNCT
dpc-2345	200	1	the	the	DET
dpc-2345	200	2	human	human	ADJ
dpc-2345	200	3	nail	nail	NOUN
dpc-2345	200	4	—	—	PUNCT
dpc-2345	200	5	barrier	barrier	NOUN
dpc-2345	200	6	characterisation	characterisation	NOUN
dpc-2345	200	7	and	and	CCONJ
dpc-2345	200	8	permeation	permeation	NOUN
dpc-2345	200	9	enhancement	enhancement	NOUN
dpc-2345	200	10	.	.	PUNCT
dpc-2345	201	1	int	int	NOUN
dpc-2345	201	2	j	j	PROPN
dpc-2345	201	3	pharm	pharm	PROPN
dpc-2345	201	4	.	.	PUNCT
dpc-2345	202	1	2012;435(1):10	2012;435(1):10	PROPN
dpc-2345	202	2	-	-	SYM
dpc-2345	202	3	21	21	NUM
dpc-2345	202	4	.	.	PUNCT
dpc-2345	203	1	doi	doi	NOUN
dpc-2345	203	2	:	:	PUNCT
dpc-2345	203	3	10.1016	10.1016	NUM
dpc-2345	203	4	/	/	SYM
dpc-2345	203	5	j.	j.	PROPN
dpc-2345	203	6	ijpharm.2012.04.024	ijpharm.2012.04.024	PROPN
dpc-2345	203	7	.	.	PUNCT
dpc-2345	204	1	pmid	pmid	NOUN
dpc-2345	204	2	:	:	PUNCT
dpc-2345	204	3	22521879	22521879	NUM
dpc-2345	204	4	.	.	PUNCT
dpc-2345	205	1	24	24	NUM
dpc-2345	205	2	.	.	PUNCT
dpc-2345	206	1	yang	yang	PROPN
dpc-2345	206	2	f	f	PROPN
dpc-2345	206	3	,	,	PUNCT
dpc-2345	206	4	yu	yu	PROPN
dpc-2345	206	5	x	x	PROPN
dpc-2345	206	6	,	,	PUNCT
dpc-2345	206	7	shao	shao	PROPN
dpc-2345	206	8	w	w	PROPN
dpc-2345	206	9	,	,	PUNCT
dpc-2345	206	10	et	et	PROPN
dpc-2345	206	11	al	al	PROPN
dpc-2345	206	12	.	.	PUNCT
dpc-2345	207	1	co	co	NOUN
dpc-2345	208	1	-	-	NOUN
dpc-2345	208	2	delivery	delivery	NOUN
dpc-2345	208	3	of	of	ADP
dpc-2345	208	4	terbinafine	terbinafine	ADJ
dpc-2345	208	5	hydrochloride	hydrochloride	NOUN
dpc-2345	208	6	and	and	CCONJ
dpc-2345	208	7	urea	urea	VERB
dpc-2345	208	8	with	with	ADP
dpc-2345	208	9	an	an	DET
dpc-2345	208	10	in	in	ADP
dpc-2345	208	11	situ	situ	ADJ
dpc-2345	208	12	film	film	NOUN
dpc-2345	208	13	-	-	PUNCT
dpc-2345	208	14	forming	form	VERB
dpc-2345	208	15	system	system	NOUN
dpc-2345	208	16	for	for	ADP
dpc-2345	208	17	nail	nail	NOUN
dpc-2345	208	18	targeting	targeting	NOUN
dpc-2345	208	19	treatment	treatment	NOUN
dpc-2345	208	20	.	.	PUNCT
dpc-2345	209	1	int	int	PROPN
dpc-2345	209	2	j	j	PROPN
dpc-2345	209	3	pharm	pharm	PROPN
dpc-2345	209	4	.	.	PUNCT
dpc-2345	210	1	2020;585:119497	2020;585:119497	X
dpc-2345	210	2	.	.	PUNCT
dpc-2345	211	1	doi	doi	NOUN
dpc-2345	211	2	:	:	PUNCT
dpc-2345	211	3	10.1016	10.1016	NUM
dpc-2345	211	4	/	/	SYM
dpc-2345	211	5	j.ijpharm.2020.119497	j.ijpharm.2020.119497	PROPN
dpc-2345	211	6	.	.	PUNCT
dpc-2345	212	1	pmid	pmid	NOUN
dpc-2345	212	2	:	:	PUNCT
dpc-2345	212	3	32504773	32504773	NUM
dpc-2345	212	4	.	.	PUNCT
dpc-2345	213	1	25	25	NUM
dpc-2345	213	2	.	.	PUNCT
dpc-2345	214	1	abdollahi	abdollahi	PROPN
dpc-2345	214	2	d	d	PROPN
dpc-2345	214	3	,	,	PUNCT
dpc-2345	214	4	jafariazar	jafariazar	PROPN
dpc-2345	214	5	z	z	PROPN
dpc-2345	214	6	,	,	PUNCT
dpc-2345	215	1	afshar	afshar	DET
dpc-2345	215	2	m.	m.	NOUN
dpc-2345	215	3	effect	effect	NOUN
dpc-2345	215	4	of	of	ADP
dpc-2345	215	5	monoterpenes	monoterpene	NOUN
dpc-2345	215	6	on	on	ADP
dpc-2345	215	7	ex	ex	PRON
dpc-2345	215	8	vivo	vivo	ADJ
dpc-2345	215	9	transungual	transungual	ADJ
dpc-2345	215	10	delivery	delivery	NOUN
dpc-2345	215	11	of	of	ADP
dpc-2345	215	12	itraconazole	itraconazole	NOUN
dpc-2345	215	13	for	for	ADP
dpc-2345	215	14	the	the	DET
dpc-2345	215	15	management	management	NOUN
dpc-2345	215	16	of	of	ADP
dpc-2345	215	17	onychomycosis	onychomycosis	NOUN
dpc-2345	215	18	.	.	PUNCT
dpc-2345	216	1	j	j	PROPN
dpc-2345	216	2	cosmet	cosmet	PROPN
dpc-2345	216	3	dermatol	dermatol	NOUN
dpc-2345	216	4	.	.	PUNCT
dpc-2345	217	1	2020;19(10):2745	2020;19(10):2745	NUM
dpc-2345	217	2	-	-	PUNCT
dpc-2345	217	3	2751	2751	NUM
dpc-2345	217	4	.	.	PUNCT
dpc-2345	218	1	doi	doi	NOUN
dpc-2345	218	2	:	:	PUNCT
dpc-2345	218	3	10.1111	10.1111	NUM
dpc-2345	218	4	/	/	SYM
dpc-2345	218	5	jocd.13317	jocd.13317	PROPN
dpc-2345	218	6	.	.	PUNCT
dpc-2345	218	7	pmid	pmid	NOUN
dpc-2345	218	8	:	:	PUNCT
dpc-2345	218	9	32043759	32043759	NUM
dpc-2345	218	10	.	.	PUNCT
dpc-2345	219	1	26	26	NUM
dpc-2345	219	2	.	.	PUNCT
dpc-2345	219	3	saner	sane	ADJ
dpc-2345	219	4	mv	mv	PROPN
dpc-2345	219	5	,	,	PUNCT
dpc-2345	219	6	kulkarni	kulkarni	PROPN
dpc-2345	219	7	ad	ad	NOUN
dpc-2345	219	8	,	,	PUNCT
dpc-2345	219	9	pardeshi	pardeshi	PROPN
dpc-2345	219	10	cv	cv	PROPN
dpc-2345	219	11	.	.	PROPN
dpc-2345	220	1	insights	insight	NOUN
dpc-2345	220	2	into	into	ADP
dpc-2345	220	3	drug	drug	NOUN
dpc-2345	220	4	delivery	delivery	NOUN
dpc-2345	220	5	across	across	ADP
dpc-2345	220	6	the	the	DET
dpc-2345	220	7	nail	nail	NOUN
dpc-2345	220	8	plate	plate	NOUN
dpc-2345	220	9	barrier	barrier	NOUN
dpc-2345	220	10	.	.	PUNCT
dpc-2345	221	1	j	j	PROPN
dpc-2345	221	2	drug	drug	NOUN
dpc-2345	221	3	target	target	NOUN
dpc-2345	221	4	.	.	PUNCT
dpc-2345	222	1	2014;22(9):769	2014;22(9):769	NUM
dpc-2345	222	2	-	-	PUNCT
dpc-2345	222	3	789	789	NUM
dpc-2345	222	4	.	.	PUNCT
dpc-2345	223	1	doi	doi	NOUN
dpc-2345	223	2	:	:	PUNCT
dpc-2345	223	3	10.3109/1061186x.2014.929138	10.3109/1061186x.2014.929138	PROPN
dpc-2345	223	4	.	.	PUNCT
dpc-2345	224	1	pmid	pmid	NOUN
dpc-2345	224	2	:	:	PUNCT
dpc-2345	224	3	24964054	24964054	NUM
dpc-2345	224	4	.	.	PUNCT
dpc-2345	225	1	the	the	DET
dpc-2345	225	2	present	present	ADJ
dpc-2345	225	3	study	study	NOUN
dpc-2345	225	4	concludes	conclude	VERB
dpc-2345	225	5	that	that	SCONJ
dpc-2345	225	6	terpenes	terpene	NOUN
dpc-2345	225	7	including	include	VERB
dpc-2345	225	8	lavandulol	lavandulol	NOUN
dpc-2345	225	9	,	,	PUNCT
dpc-2345	225	10	safranal	safranal	ADJ
dpc-2345	225	11	,	,	PUNCT
dpc-2345	225	12	rose	rise	VERB
dpc-2345	225	13	oxide	oxide	NOUN
dpc-2345	225	14	,	,	PUNCT
dpc-2345	225	15	limonene	limonene	NOUN
dpc-2345	225	16	,	,	PUNCT
dpc-2345	225	17	3	3	NUM
dpc-2345	225	18	-	-	PUNCT
dpc-2345	225	19	methyl-2	methyl-2	PROPN
dpc-2345	225	20	-	-	PUNCT
dpc-2345	225	21	butene1	butene1	NOUN
dpc-2345	225	22	-	-	PUNCT
dpc-2345	225	23	ol	ol	PROPN
dpc-2345	225	24	,	,	PUNCT
dpc-2345	225	25	and	and	CCONJ
dpc-2345	225	26	linalool	linalool	NOUN
dpc-2345	225	27	accentuate	accentuate	VERB
dpc-2345	225	28	the	the	DET
dpc-2345	225	29	transungual	transungual	ADJ
dpc-2345	225	30	penetration	penetration	NOUN
dpc-2345	225	31	of	of	ADP
dpc-2345	225	32	terbinafine	terbinafine	NOUN
dpc-2345	225	33	and	and	CCONJ
dpc-2345	225	34	among	among	ADP
dpc-2345	225	35	these	these	PRON
dpc-2345	225	36	,	,	PUNCT
dpc-2345	225	37	linalool	linalool	NOUN
dpc-2345	225	38	has	have	AUX
dpc-2345	225	39	been	be	AUX
dpc-2345	225	40	found	find	VERB
dpc-2345	225	41	to	to	PART
dpc-2345	225	42	be	be	AUX
dpc-2345	225	43	the	the	DET
dpc-2345	225	44	most	most	ADV
dpc-2345	225	45	effective	effective	ADJ
dpc-2345	225	46	penetration	penetration	NOUN
dpc-2345	225	47	enhancer	enhancer	NOUN
dpc-2345	225	48	for	for	ADP
dpc-2345	225	49	the	the	DET
dpc-2345	225	50	transungual	transungual	ADJ
dpc-2345	225	51	delivery	delivery	NOUN
dpc-2345	225	52	of	of	ADP
dpc-2345	225	53	terbinafine	terbinafine	NOUN
dpc-2345	225	54	.	.	PUNCT
dpc-2345	226	1	by	by	ADP
dpc-2345	226	2	virtue	virtue	NOUN
dpc-2345	226	3	of	of	ADP
dpc-2345	226	4	their	their	PRON
dpc-2345	226	5	enhancing	enhance	VERB
dpc-2345	226	6	effect	effect	NOUN
dpc-2345	226	7	,	,	PUNCT
dpc-2345	226	8	formulation	formulation	NOUN
dpc-2345	226	9	of	of	ADP
dpc-2345	226	10	terbinafine	terbinafine	NOUN
dpc-2345	226	11	with	with	ADP
dpc-2345	226	12	one	one	NUM
dpc-2345	226	13	or	or	CCONJ
dpc-2345	226	14	combination	combination	NOUN
dpc-2345	226	15	of	of	ADP
dpc-2345	226	16	these	these	DET
dpc-2345	226	17	terpenes	terpene	NOUN
dpc-2345	226	18	could	could	AUX
dpc-2345	226	19	be	be	AUX
dpc-2345	226	20	beneficial	beneficial	ADJ
dpc-2345	226	21	in	in	ADP
dpc-2345	226	22	topical	topical	ADJ
dpc-2345	226	23	dosage	dosage	NOUN
dpc-2345	226	24	form	form	NOUN
dpc-2345	226	25	development	development	NOUN
dpc-2345	226	26	for	for	ADP
dpc-2345	226	27	treatment	treatment	NOUN
dpc-2345	226	28	of	of	ADP
dpc-2345	226	29	onychomycosis	onychomycosis	NOUN
dpc-2345	226	30	.	.	PUNCT
dpc-2345	227	1	references	reference	NOUN
dpc-2345	227	2	1	1	NUM
dpc-2345	227	3	.	.	PUNCT
dpc-2345	227	4	gupta	gupta	PROPN
dpc-2345	227	5	ak	ak	PROPN
dpc-2345	227	6	,	,	PUNCT
dpc-2345	227	7	stec	stec	ADJ
dpc-2345	227	8	n.	n.	PROPN
dpc-2345	227	9	recent	recent	ADJ
dpc-2345	227	10	advances	advance	NOUN
dpc-2345	227	11	in	in	ADP
dpc-2345	227	12	therapies	therapy	NOUN
dpc-2345	227	13	for	for	ADP
dpc-2345	227	14	onychomycosis	onychomycosis	NOUN
dpc-2345	227	15	and	and	CCONJ
dpc-2345	227	16	its	its	PRON
dpc-2345	227	17	management	management	NOUN
dpc-2345	227	18	.	.	PUNCT
dpc-2345	228	1	f1000res	f1000res	PROPN
dpc-2345	228	2	.	.	PUNCT
dpc-2345	228	3	2019;8	2019;8	NOUN
dpc-2345	228	4	:	:	PUNCT
dpc-2345	228	5	f1000	f1000	PROPN
dpc-2345	228	6	faculty	faculty	NOUN
dpc-2345	228	7	rev-968	rev-968	NOUN
dpc-2345	228	8	.	.	PUNCT
dpc-2345	229	1	doi	doi	NOUN
dpc-2345	229	2	:	:	PUNCT
dpc-2345	229	3	10.12688	10.12688	NUM
dpc-2345	229	4	/	/	SYM
dpc-2345	229	5	f1000research.18646.1	f1000research.18646.1	PROPN
dpc-2345	229	6	.	.	PUNCT
dpc-2345	230	1	pmid	pmid	NOUN
dpc-2345	230	2	:	:	PUNCT
dpc-2345	230	3	31297182	31297182	NUM
dpc-2345	230	4	.	.	PUNCT
dpc-2345	231	1	pmcid	pmcid	NOUN
dpc-2345	231	2	:	:	PUNCT
dpc-2345	231	3	pmc6600855	pmc6600855	ADJ
dpc-2345	231	4	.	.	PUNCT
dpc-2345	232	1	2	2	X
dpc-2345	232	2	.	.	X
dpc-2345	232	3	lipner	lipner	PROPN
dpc-2345	232	4	sr	sr	PROPN
dpc-2345	232	5	,	,	PUNCT
dpc-2345	232	6	scher	scher	PROPN
dpc-2345	232	7	rk	rk	PROPN
dpc-2345	232	8	.	.	PUNCT
dpc-2345	232	9	onychomycosis	onychomycosis	NOUN
dpc-2345	232	10	:	:	PUNCT
dpc-2345	232	11	treatment	treatment	NOUN
dpc-2345	232	12	and	and	CCONJ
dpc-2345	232	13	prevention	prevention	NOUN
dpc-2345	232	14	of	of	ADP
dpc-2345	232	15	recurrence	recurrence	NOUN
dpc-2345	232	16	.	.	PUNCT
dpc-2345	233	1	j	j	PROPN
dpc-2345	233	2	am	be	AUX
dpc-2345	233	3	acad	acad	ADJ
dpc-2345	233	4	dermatol	dermatol	NOUN
dpc-2345	233	5	.	.	PUNCT
dpc-2345	234	1	2019;80(4):853–867	2019;80(4):853–867	NUM
dpc-2345	234	2	.	.	PUNCT
dpc-2345	235	1	doi	doi	NOUN
dpc-2345	235	2	:	:	PUNCT
dpc-2345	235	3	10.1016	10.1016	NUM
dpc-2345	235	4	/	/	SYM
dpc-2345	235	5	j.jaad.2018.05.1260	j.jaad.2018.05.1260	NOUN
dpc-2345	235	6	.	.	PUNCT
dpc-2345	236	1	pmid	pmid	NOUN
dpc-2345	236	2	:	:	PUNCT
dpc-2345	236	3	29959962	29959962	NUM
dpc-2345	236	4	.	.	PUNCT
dpc-2345	237	1	3	3	X
dpc-2345	237	2	.	.	PUNCT
dpc-2345	237	3	elkeeb	elkeeb	NOUN
dpc-2345	237	4	r	r	PROPN
dpc-2345	237	5	,	,	PUNCT
dpc-2345	237	6	alikhan	alikhan	ADV
dpc-2345	237	7	a	a	PRON
dpc-2345	237	8	,	,	PUNCT
dpc-2345	237	9	elkeeb	elkeeb	NOUN
dpc-2345	237	10	l	l	PROPN
dpc-2345	237	11	,	,	PUNCT
dpc-2345	237	12	hui	hui	PROPN
dpc-2345	237	13	x	x	X
dpc-2345	237	14	,	,	PUNCT
dpc-2345	237	15	maibach	maibach	PROPN
dpc-2345	237	16	hi	hi	PROPN
dpc-2345	237	17	.	.	PUNCT
dpc-2345	238	1	transungual	transungual	ADJ
dpc-2345	238	2	drug	drug	NOUN
dpc-2345	238	3	delivery	delivery	NOUN
dpc-2345	238	4	:	:	PUNCT
dpc-2345	238	5	current	current	ADJ
dpc-2345	238	6	status	status	NOUN
dpc-2345	238	7	.	.	PUNCT
dpc-2345	239	1	int	int	PROPN
dpc-2345	239	2	j	j	PROPN
dpc-2345	239	3	pharm	pharm	PROPN
dpc-2345	239	4	.	.	PUNCT
dpc-2345	240	1	2010;384(1	2010;384(1	NUM
dpc-2345	240	2	-	-	PUNCT
dpc-2345	240	3	2):1	2):1	NUM
dpc-2345	240	4	-	-	PUNCT
dpc-2345	240	5	8	8	NUM
dpc-2345	240	6	.	.	PUNCT
dpc-2345	241	1	doi	doi	NOUN
dpc-2345	241	2	:	:	PUNCT
dpc-2345	241	3	10.1016	10.1016	NUM
dpc-2345	241	4	/	/	SYM
dpc-2345	241	5	j.ijpharm.2009.10.002	j.ijpharm.2009.10.002	PROPN
dpc-2345	241	6	.	.	PUNCT
dpc-2345	242	1	pmid	pmid	NOUN
dpc-2345	242	2	:	:	PUNCT
dpc-2345	242	3	19819318	19819318	NUM
dpc-2345	242	4	.	.	PUNCT
dpc-2345	243	1	4	4	X
dpc-2345	243	2	.	.	X
dpc-2345	243	3	gupta	gupta	PROPN
dpc-2345	243	4	ak	ak	PROPN
dpc-2345	243	5	,	,	PUNCT
dpc-2345	243	6	ryder	ryder	PROPN
dpc-2345	243	7	je	je	PROPN
dpc-2345	243	8	,	,	PUNCT
dpc-2345	243	9	johnson	johnson	PROPN
dpc-2345	243	10	am	be	AUX
dpc-2345	243	11	.	.	PUNCT
dpc-2345	244	1	cumulative	cumulative	VERB
dpc-2345	244	2	meta	meta	ADJ
dpc-2345	244	3	-	-	PUNCT
dpc-2345	244	4	analysis	analysis	NOUN
dpc-2345	244	5	of	of	ADP
dpc-2345	244	6	systemic	systemic	ADJ
dpc-2345	244	7	antifungal	antifungal	ADJ
dpc-2345	244	8	agents	agent	NOUN
dpc-2345	244	9	for	for	ADP
dpc-2345	244	10	the	the	DET
dpc-2345	244	11	treatment	treatment	NOUN
dpc-2345	244	12	of	of	ADP
dpc-2345	244	13	onychomycosis	onychomycosis	NOUN
dpc-2345	244	14	.	.	PUNCT
dpc-2345	245	1	br	br	PROPN
dpc-2345	245	2	j	j	PROPN
dpc-2345	245	3	dermatol	dermatol	NOUN
dpc-2345	245	4	.	.	PUNCT
dpc-2345	246	1	2004	2004	NUM
dpc-2345	246	2	;	;	PUNCT
dpc-2345	247	1	150(3):537	150(3):537	NUM
dpc-2345	247	2	-	-	SYM
dpc-2345	247	3	544	544	NUM
dpc-2345	247	4	.	.	PUNCT
dpc-2345	247	5	doi	doi	NOUN
dpc-2345	247	6	:	:	PUNCT
dpc-2345	247	7	10.1046	10.1046	NUM
dpc-2345	247	8	/	/	SYM
dpc-2345	247	9	j.1365	j.1365	NOUN
dpc-2345	247	10	-2133.2003.05728.x	-2133.2003.05728.x	VERB
dpc-2345	247	11	.	.	PUNCT
dpc-2345	248	1	pmid	pmid	NOUN
dpc-2345	248	2	:	:	PUNCT
dpc-2345	248	3	15030339	15030339	NUM
dpc-2345	248	4	.	.	PUNCT
dpc-2345	249	1	5	5	X
dpc-2345	249	2	.	.	PUNCT
dpc-2345	249	3	antifungal	antifungal	ADJ
dpc-2345	249	4	drugs	drug	NOUN
dpc-2345	249	5	.	.	PUNCT
dpc-2345	250	1	treat	treat	VERB
dpc-2345	250	2	guidel	guidel	PROPN
dpc-2345	250	3	med	med	PROPN
dpc-2345	250	4	lett	lett	PROPN
dpc-2345	250	5	.	.	PUNCT
dpc-2345	251	1	2009;7(88):95	2009;7(88):95	NUM
dpc-2345	251	2	-	-	PUNCT
dpc-2345	251	3	102	102	NUM
dpc-2345	251	4	.	.	PUNCT
dpc-2345	252	1	pmid	pmid	NOUN
dpc-2345	252	2	:	:	PUNCT
dpc-2345	252	3	19940816	19940816	NUM
dpc-2345	252	4	.	.	PUNCT
dpc-2345	253	1	6	6	NUM
dpc-2345	253	2	.	.	X
dpc-2345	253	3	bennett	bennett	PROPN
dpc-2345	253	4	je	je	PROPN
dpc-2345	253	5	.	.	PROPN
dpc-2345	253	6	antifungal	antifungal	PROPN
dpc-2345	253	7	agents	agent	NOUN
dpc-2345	253	8	.	.	PUNCT
dpc-2345	254	1	in	in	ADP
dpc-2345	254	2	:	:	PUNCT
dpc-2345	254	3	brunton	brunton	PROPN
dpc-2345	254	4	l	l	PROPN
dpc-2345	254	5	,	,	PUNCT
dpc-2345	254	6	chabner	chabner	PROPN
dpc-2345	254	7	b	b	PROPN
dpc-2345	254	8	,	,	PUNCT
dpc-2345	254	9	knollman	knollman	PROPN
dpc-2345	254	10	b	b	PROPN
dpc-2345	254	11	,	,	PUNCT
dpc-2345	254	12	eds	eds	PROPN
dpc-2345	254	13	.	.	PROPN
dpc-2345	254	14	goodman	goodman	PROPN
dpc-2345	254	15	&	&	CCONJ
dpc-2345	254	16	gilman	gilman	PROPN
dpc-2345	254	17	's	's	PART
dpc-2345	254	18	the	the	DET
dpc-2345	254	19	pharmacological	pharmacological	ADJ
dpc-2345	254	20	basis	basis	NOUN
dpc-2345	254	21	of	of	ADP
dpc-2345	254	22	therapeutics	therapeutic	NOUN
dpc-2345	254	23	.	.	PUNCT
dpc-2345	255	1	12th	12th	ADJ
dpc-2345	255	2	ed	ed	NOUN
dpc-2345	255	3	.	.	PUNCT
dpc-2345	256	1	new	new	PROPN
dpc-2345	256	2	york	york	PROPN
dpc-2345	256	3	,	,	PUNCT
dpc-2345	256	4	ny	ny	PROPN
dpc-2345	256	5	:	:	PUNCT
dpc-2345	256	6	mcgraw	mcgraw	PROPN
dpc-2345	256	7	-	-	PUNCT
dpc-2345	256	8	hill	hill	PROPN
dpc-2345	256	9	;	;	PUNCT
dpc-2345	256	10	2011:1571	2011:1571	NUM
dpc-2345	256	11	-	-	SYM
dpc-2345	256	12	1592	1592	NUM
dpc-2345	256	13	.	.	PUNCT
dpc-2345	257	1	7	7	X
dpc-2345	257	2	.	.	X
dpc-2345	257	3	darkes	darke	NOUN
dpc-2345	257	4	mj	mj	PROPN
dpc-2345	257	5	,	,	PUNCT
dpc-2345	257	6	scott	scott	PROPN
dpc-2345	257	7	lj	lj	PROPN
dpc-2345	257	8	,	,	PUNCT
dpc-2345	257	9	goa	goa	PROPN
dpc-2345	257	10	kl	kl	PROPN
dpc-2345	257	11	.	.	PROPN
dpc-2345	257	12	terbinafine	terbinafine	PROPN
dpc-2345	257	13	:	:	PUNCT
dpc-2345	257	14	a	a	DET
dpc-2345	257	15	review	review	NOUN
dpc-2345	257	16	of	of	ADP
dpc-2345	257	17	its	its	PRON
dpc-2345	257	18	use	use	NOUN
dpc-2345	257	19	in	in	ADP
dpc-2345	257	20	onychomycosis	onychomycosis	NOUN
dpc-2345	257	21	in	in	ADP
dpc-2345	257	22	adults	adult	NOUN
dpc-2345	257	23	.	.	PUNCT
dpc-2345	258	1	am	be	AUX
dpc-2345	258	2	j	j	PROPN
dpc-2345	258	3	clin	clin	PROPN
dpc-2345	258	4	dermatol	dermatol	NOUN
dpc-2345	258	5	.	.	PUNCT
dpc-2345	259	1	2003;4(1):39	2003;4(1):39	NUM
dpc-2345	259	2	-	-	SYM
dpc-2345	259	3	65	65	NUM
dpc-2345	259	4	.	.	PUNCT
dpc-2345	260	1	doi	doi	NOUN
dpc-2345	260	2	:	:	PUNCT
dpc-2345	260	3	10.2165/00128071	10.2165/00128071	NUM
dpc-2345	260	4	-	-	SYM
dpc-2345	260	5	200304010	200304010	NUM
dpc-2345	260	6	-	-	PUNCT
dpc-2345	260	7	00005	00005	NUM
dpc-2345	260	8	.	.	PUNCT
dpc-2345	261	1	pmid	pmid	NOUN
dpc-2345	261	2	:	:	PUNCT
dpc-2345	261	3	12477372	12477372	NUM
dpc-2345	261	4	.	.	PUNCT
dpc-2345	262	1	8	8	X
dpc-2345	262	2	.	.	X
dpc-2345	262	3	angelo	angelo	PROPN
dpc-2345	262	4	t	t	PROPN
dpc-2345	262	5	,	,	PUNCT
dpc-2345	262	6	borgheti	borgheti	PROPN
dpc-2345	262	7	-	-	NOUN
dpc-2345	262	8	cardoso	cardoso	NOUN
dpc-2345	262	9	ln	ln	PROPN
dpc-2345	262	10	,	,	PUNCT
dpc-2345	262	11	gelfuso	gelfuso	PROPN
dpc-2345	262	12	gm	gm	PROPN
dpc-2345	262	13	.	.	PUNCT
dpc-2345	262	14	chemical	chemical	PROPN
dpc-2345	262	15	and	and	CCONJ
dpc-2345	262	16	physical	physical	ADJ
dpc-2345	262	17	strategies	strategy	NOUN
dpc-2345	262	18	in	in	ADP
dpc-2345	262	19	onychomycosis	onychomycosis	NOUN
dpc-2345	262	20	topical	topical	ADJ
dpc-2345	262	21	treatment	treatment	NOUN
dpc-2345	262	22	:	:	PUNCT
dpc-2345	262	23	a	a	DET
dpc-2345	262	24	review	review	NOUN
dpc-2345	262	25	.	.	PUNCT
dpc-2345	263	1	med	med	PROPN
dpc-2345	263	2	mycol	mycol	NOUN
dpc-2345	263	3	.	.	PUNCT
dpc-2345	264	1	2017;55(5):461–475	2017;55(5):461–475	X
dpc-2345	264	2	.	.	PUNCT
dpc-2345	264	3	doi	doi	NOUN
dpc-2345	264	4	:	:	PUNCT
dpc-2345	264	5	10.1093	10.1093	NUM
dpc-2345	264	6	/	/	SYM
dpc-2345	264	7	mmy	mmy	PROPN
dpc-2345	264	8	/	/	SYM
dpc-2345	264	9	myw084	myw084	PROPN
dpc-2345	264	10	.	.	PUNCT
dpc-2345	265	1	pmid	pmid	NOUN
dpc-2345	265	2	:	:	PUNCT
dpc-2345	265	3	27703019	27703019	NUM
dpc-2345	265	4	.	.	PUNCT
dpc-2345	266	1	9	9	X
dpc-2345	266	2	.	.	X
dpc-2345	266	3	gupta	gupta	PROPN
dpc-2345	266	4	ak	ak	PROPN
dpc-2345	266	5	,	,	PUNCT
dpc-2345	266	6	scher	scher	PROPN
dpc-2345	266	7	rk	rk	PROPN
dpc-2345	266	8	.	.	PUNCT
dpc-2345	266	9	management	management	NOUN
dpc-2345	266	10	of	of	ADP
dpc-2345	266	11	onychomycosis	onychomycosis	NOUN
dpc-2345	266	12	:	:	PUNCT
dpc-2345	266	13	a	a	DET
dpc-2345	266	14	north	north	NOUN
dpc-2345	266	15	american	american	ADJ
dpc-2345	266	16	perspective	perspective	NOUN
dpc-2345	266	17	.	.	PUNCT
dpc-2345	267	1	dermatologic	dermatologic	ADJ
dpc-2345	267	2	ther	ther	ADV
dpc-2345	267	3	.	.	PUNCT
dpc-2345	268	1	1997	1997	NUM
dpc-2345	268	2	;	;	PUNCT
dpc-2345	268	3	3	3	NUM
dpc-2345	268	4	:	:	SYM
dpc-2345	268	5	58	58	NUM
dpc-2345	268	6	-	-	SYM
dpc-2345	268	7	65	65	NUM
dpc-2345	268	8	'	'	NUM
dpc-2345	268	9	10	10	NUM
dpc-2345	268	10	.	.	PUNCT
dpc-2345	268	11	gupta	gupta	PROPN
dpc-2345	268	12	ak	ak	PROPN
dpc-2345	268	13	,	,	PUNCT
dpc-2345	268	14	scher	scher	PROPN
dpc-2345	268	15	rk	rk	PROPN
dpc-2345	268	16	,	,	PUNCT
dpc-2345	268	17	de	de	X
dpc-2345	268	18	doncker	doncker	PROPN
dpc-2345	268	19	p.	p.	PROPN
dpc-2345	268	20	current	current	ADJ
dpc-2345	268	21	management	management	NOUN
dpc-2345	268	22	of	of	ADP
dpc-2345	268	23	onychomycosis	onychomycosis	NOUN
dpc-2345	268	24	:	:	PUNCT
dpc-2345	268	25	an	an	DET
dpc-2345	268	26	overview	overview	NOUN
dpc-2345	268	27	.	.	PUNCT
dpc-2345	269	1	derm	derm	NOUN
dpc-2345	269	2	clinics.1997;15(1):121	clinics.1997;15(1):121	PROPN
dpc-2345	269	3	-	-	PUNCT
dpc-2345	269	4	135	135	NUM
dpc-2345	269	5	.	.	PUNCT
dpc-2345	269	6	doi	doi	NOUN
dpc-2345	269	7	:	:	PUNCT
dpc-2345	269	8	10.1016	10.1016	NUM
dpc-2345	269	9	/	/	SYM
dpc-2345	269	10	s0733	s0733	NOUN
dpc-2345	269	11	-	-	PUNCT
dpc-2345	269	12	8635(05)70420	8635(05)70420	NUM
dpc-2345	269	13	-	-	PUNCT
dpc-2345	269	14	4	4	NUM
dpc-2345	269	15	.	.	PUNCT
dpc-2345	270	1	pmid	pmid	NOUN
dpc-2345	270	2	:	:	PUNCT
dpc-2345	270	3	9001866	9001866	NUM
dpc-2345	270	4	.	.	PUNCT
dpc-2345	271	1	11	11	NUM
dpc-2345	271	2	.	.	X
dpc-2345	271	3	gupta	gupta	PROPN
dpc-2345	271	4	ak	ak	PROPN
dpc-2345	271	5	,	,	PUNCT
dpc-2345	271	6	sauder	sauder	NOUN
dpc-2345	271	7	on	on	ADP
dpc-2345	271	8	,	,	PUNCT
dpc-2345	271	9	shear	shear	PROPN
dpc-2345	271	10	nh	nh	PROPN
dpc-2345	271	11	.	.	PROPN
dpc-2345	271	12	antifungal	antifungal	PROPN
dpc-2345	271	13	agents	agent	NOUN
dpc-2345	271	14	:	:	PUNCT
dpc-2345	271	15	an	an	DET
dpc-2345	271	16	overview	overview	NOUN
dpc-2345	271	17	.	.	PUNCT
dpc-2345	272	1	part	part	NOUN
dpc-2345	272	2	1	1	NUM
dpc-2345	272	3	.	.	PUNCT
dpc-2345	272	4	am	be	AUX
dpc-2345	272	5	acad	acad	ADJ
dpc-2345	272	6	dermatol	dermatol	NOUN
dpc-2345	272	7	.	.	PUNCT
dpc-2345	273	1	1994;30(5	1994;30(5	NUM
dpc-2345	273	2	pt	pt	NOUN
dpc-2345	273	3	1):677	1):677	NUM
dpc-2345	273	4	-	-	PUNCT
dpc-2345	273	5	698	698	NUM
dpc-2345	273	6	;	;	PUNCT
dpc-2345	273	7	quiz	quiz	NOUN
dpc-2345	273	8	698	698	NUM
dpc-2345	273	9	-	-	SYM
dpc-2345	273	10	700	700	NUM
dpc-2345	273	11	.	.	PUNCT
dpc-2345	274	1	pmid	pmid	NOUN
dpc-2345	274	2	:	:	PUNCT
dpc-2345	274	3	8176006	8176006	NUM
dpc-2345	274	4	.	.	PUNCT
dpc-2345	275	1	30	30	NUM
dpc-2345	275	2	:	:	PUNCT
dpc-2345	275	3	677	677	NUM
dpc-2345	275	4	-	-	SYM
dpc-2345	275	5	698	698	NUM
dpc-2345	275	6	.	.	PUNCT
dpc-2345	276	1	12	12	NUM
dpc-2345	276	2	.	.	PUNCT
dpc-2345	277	1	gupta	gupta	PROPN
dpc-2345	277	2	ak	ak	PROPN
dpc-2345	277	3	,	,	PUNCT
dpc-2345	277	4	sauder	sauder	NOUN
dpc-2345	277	5	on	on	ADP
dpc-2345	277	6	,	,	PUNCT
dpc-2345	277	7	shear	shear	PROPN
dpc-2345	277	8	nh	nh	PROPN
dpc-2345	277	9	.	.	PROPN
dpc-2345	277	10	antifungal	antifungal	PROPN
dpc-2345	277	11	agents	agent	NOUN
dpc-2345	277	12	:	:	PUNCT
dpc-2345	277	13	an	an	DET
dpc-2345	277	14	overview	overview	NOUN
dpc-2345	277	15	.	.	PUNCT
dpc-2345	278	1	part	part	PROPN
dpc-2345	278	2	ii	ii	PROPN
dpc-2345	278	3	.	.	PROPN
dpc-2345	278	4	am	be	AUX
dpc-2345	278	5	acad	acad	ADJ
dpc-2345	278	6	dermatol	dermatol	NOUN
dpc-2345	278	7	.	.	PUNCT
dpc-2345	279	1	1994;30(6):911	1994;30(6):911	NUM
dpc-2345	279	2	-	-	PUNCT
dpc-2345	279	3	933	933	NUM
dpc-2345	279	4	;	;	PUNCT
dpc-2345	279	5	quiz	quiz	NOUN
dpc-2345	279	6	934	934	NUM
dpc-2345	279	7	-	-	SYM
dpc-2345	279	8	6	6	NUM
dpc-2345	279	9	.	.	PUNCT
dpc-2345	279	10	doi	doi	NOUN
dpc-2345	279	11	:	:	PUNCT
dpc-2345	279	12	10.1016	10.1016	NUM
dpc-2345	279	13	/	/	SYM
dpc-2345	279	14	s0190	s0190	VERB
dpc-2345	279	15	-	-	PUNCT
dpc-2345	279	16	9622(94)70112	9622(94)70112	NUM
dpc-2345	279	17	-	-	PUNCT
dpc-2345	279	18	1	1	NUM
dpc-2345	279	19	.	.	PUNCT
dpc-2345	280	1	pmid	pmid	NOUN
dpc-2345	280	2	:	:	PUNCT
dpc-2345	280	3	7619094	7619094	NUM
dpc-2345	280	4	.	.	PUNCT