id	sid	tid	token	lemma	pos
dpc-2653	1	1	dermatology	dermatology	NOUN
dpc-2653	1	2	:	:	PUNCT
dpc-2653	1	3	practical	practical	ADJ
dpc-2653	1	4	and	and	CCONJ
dpc-2653	1	5	conceptual	conceptual	ADJ
dpc-2653	1	6	review	review	NOUN
dpc-2653	1	7	|	|	ADV
dpc-2653	1	8	dermatol	dermatol	ADJ
dpc-2653	1	9	pract	pract	NOUN
dpc-2653	1	10	concept	concept	NOUN
dpc-2653	1	11	.	.	PUNCT
dpc-2653	2	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	2	2	1	1	NUM
dpc-2653	2	3	narrative	narrative	NOUN
dpc-2653	2	4	review	review	NOUN
dpc-2653	2	5	of	of	ADP
dpc-2653	2	6	drug	drug	NOUN
dpc-2653	2	7	-	-	PUNCT
dpc-2653	2	8	associated	associate	VERB
dpc-2653	2	9	nail	nail	NOUN
dpc-2653	2	10	toxicities	toxicity	NOUN
dpc-2653	2	11	in	in	ADP
dpc-2653	2	12	oncologic	oncologic	ADJ
dpc-2653	2	13	patients	patient	NOUN
dpc-2653	2	14	anastasia	anastasia	PROPN
dpc-2653	2	15	emvalomati1	emvalomati1	PROPN
dpc-2653	2	16	,	,	PUNCT
dpc-2653	2	17	valentina	valentina	PROPN
dpc-2653	2	18	oflidou1	oflidou1	PROPN
dpc-2653	2	19	,	,	PUNCT
dpc-2653	2	20	chryssoula	chryssoula	PROPN
dpc-2653	2	21	papageorgiou1	papageorgiou1	PROPN
dpc-2653	2	22	,	,	PUNCT
dpc-2653	2	23	christina	christina	PROPN
dpc-2653	2	24	kemanetzi1	kemanetzi1	PROPN
dpc-2653	2	25	,	,	PUNCT
dpc-2653	2	26	maria	maria	PROPN
dpc-2653	2	27	giannouli1	giannouli1	PROPN
dpc-2653	2	28	,	,	PUNCT
dpc-2653	2	29	evangelia	evangelia	PROPN
dpc-2653	2	30	kalloniati1	kalloniati1	PROPN
dpc-2653	2	31	,	,	PUNCT
dpc-2653	2	32	konstantinos	konstantinos	PROPN
dpc-2653	2	33	efthymiadis2	efthymiadis2	PROPN
dpc-2653	2	34	,	,	PUNCT
dpc-2653	2	35	chrysanthi	chrysanthi	PROPN
dpc-2653	2	36	koukoutzeli2	koukoutzeli2	PROPN
dpc-2653	2	37	,	,	PUNCT
dpc-2653	2	38	eleni	eleni	PROPN
dpc-2653	2	39	timotheadou2	timotheadou2	PROPN
dpc-2653	2	40	,	,	PUNCT
dpc-2653	2	41	anastasia	anastasia	PROPN
dpc-2653	2	42	trigoni1	trigoni1	PROPN
dpc-2653	2	43	,	,	PUNCT
dpc-2653	2	44	aikaterini	aikaterini	PROPN
dpc-2653	2	45	patsatsi1	patsatsi1	PROPN
dpc-2653	2	46	,	,	PUNCT
dpc-2653	2	47	elizabeth	elizabeth	PROPN
dpc-2653	2	48	lazaridou1	lazaridou1	PROPN
dpc-2653	2	49	,	,	PUNCT
dpc-2653	2	50	zoe	zoe	PROPN
dpc-2653	2	51	apalla1	apalla1	PROPN
dpc-2653	2	52	,	,	PUNCT
dpc-2653	2	53	myrtotrakatelli1	myrtotrakatelli1	NOUN
dpc-2653	2	54	1	1	NUM
dpc-2653	2	55	second	second	ADJ
dpc-2653	2	56	department	department	NOUN
dpc-2653	2	57	of	of	ADP
dpc-2653	2	58	dermatology	dermatology	NOUN
dpc-2653	2	59	,	,	PUNCT
dpc-2653	2	60	aristotle	aristotle	PROPN
dpc-2653	2	61	university	university	PROPN
dpc-2653	2	62	of	of	ADP
dpc-2653	2	63	thessaloniki	thessaloniki	PROPN
dpc-2653	2	64	,	,	PUNCT
dpc-2653	2	65	“	"	PUNCT
dpc-2653	2	66	papageorgiou	papageorgiou	NOUN
dpc-2653	2	67	”	"	PUNCT
dpc-2653	2	68	general	general	ADJ
dpc-2653	2	69	hospital	hospital	NOUN
dpc-2653	2	70	,	,	PUNCT
dpc-2653	2	71	thessaloniki	thessaloniki	PROPN
dpc-2653	2	72	,	,	PUNCT
dpc-2653	2	73	greece	greece	PROPN
dpc-2653	2	74	2	2	NUM
dpc-2653	2	75	department	department	NOUN
dpc-2653	2	76	of	of	ADP
dpc-2653	2	77	medical	medical	ADJ
dpc-2653	2	78	oncology	oncology	NOUN
dpc-2653	2	79	,	,	PUNCT
dpc-2653	2	80	aristotle	aristotle	PROPN
dpc-2653	2	81	university	university	PROPN
dpc-2653	2	82	of	of	ADP
dpc-2653	2	83	thessaloniki	thessaloniki	PROPN
dpc-2653	2	84	,	,	PUNCT
dpc-2653	2	85	“	"	PUNCT
dpc-2653	2	86	papageorgiou	papageorgiou	NOUN
dpc-2653	2	87	”	"	PUNCT
dpc-2653	2	88	general	general	ADJ
dpc-2653	2	89	hospital	hospital	NOUN
dpc-2653	2	90	,	,	PUNCT
dpc-2653	2	91	thessaloniki	thessaloniki	PROPN
dpc-2653	2	92	,	,	PUNCT
dpc-2653	2	93	greece	greece	PROPN
dpc-2653	2	94	key	key	ADJ
dpc-2653	2	95	words	word	NOUN
dpc-2653	2	96	:	:	PUNCT
dpc-2653	2	97	nail	nail	NOUN
dpc-2653	2	98	toxicity	toxicity	NOUN
dpc-2653	2	99	,	,	PUNCT
dpc-2653	2	100	nail	nail	NOUN
dpc-2653	2	101	changes	change	NOUN
dpc-2653	2	102	,	,	PUNCT
dpc-2653	2	103	chemotherapy	chemotherapy	NOUN
dpc-2653	2	104	,	,	PUNCT
dpc-2653	2	105	targeted	target	VERB
dpc-2653	2	106	treatment	treatment	NOUN
dpc-2653	2	107	,	,	PUNCT
dpc-2653	2	108	immune	immune	ADJ
dpc-2653	2	109	checkpoint	checkpoint	NOUN
dpc-2653	2	110	inhibitors	inhibitor	NOUN
dpc-2653	2	111	citation	citation	NOUN
dpc-2653	2	112	:	:	PUNCT
dpc-2653	2	113	emvalomati	emvalomati	PROPN
dpc-2653	2	114	a	a	PRON
dpc-2653	2	115	,	,	PUNCT
dpc-2653	2	116	oflidou	oflidou	NOUN
dpc-2653	2	117	v	v	NOUN
dpc-2653	2	118	,	,	PUNCT
dpc-2653	2	119	papageorgiou	papageorgiou	NOUN
dpc-2653	2	120	c	c	NOUN
dpc-2653	2	121	,	,	PUNCT
dpc-2653	2	122	et	et	PROPN
dpc-2653	2	123	al	al	PROPN
dpc-2653	2	124	.	.	PROPN
dpc-2653	2	125	narrative	narrative	PROPN
dpc-2653	2	126	review	review	PROPN
dpc-2653	2	127	of	of	ADP
dpc-2653	2	128	drug	drug	NOUN
dpc-2653	2	129	-	-	PUNCT
dpc-2653	2	130	associated	associate	VERB
dpc-2653	2	131	nail	nail	NOUN
dpc-2653	2	132	toxicities	toxicity	NOUN
dpc-2653	2	133	in	in	ADP
dpc-2653	2	134	oncologic	oncologic	ADJ
dpc-2653	2	135	patients	patient	NOUN
dpc-2653	2	136	.	.	PUNCT
dpc-2653	3	1	dermatol	dermatol	NOUN
dpc-2653	3	2	pract	pract	PROPN
dpc-2653	3	3	concept	concept	NOUN
dpc-2653	3	4	.	.	PUNCT
dpc-2653	4	1	2023;13(1):e2023064	2023;13(1):e2023064	X
dpc-2653	4	2	.	.	PUNCT
dpc-2653	4	3	doi	doi	PROPN
dpc-2653	4	4	:	:	PUNCT
dpc-2653	4	5	https://doi.org/10.5826/dpc.1301a64	https://doi.org/10.5826/dpc.1301a64	PROPN
dpc-2653	4	6	accepted	accept	VERB
dpc-2653	4	7	:	:	PUNCT
dpc-2653	4	8	august	august	PROPN
dpc-2653	4	9	23	23	NUM
dpc-2653	4	10	,	,	PUNCT
dpc-2653	4	11	2022	2022	NUM
dpc-2653	4	12	;	;	PUNCT
dpc-2653	4	13	published	publish	VERB
dpc-2653	4	14	:	:	PUNCT
dpc-2653	4	15	january	january	NOUN
dpc-2653	4	16	2023	2023	NUM
dpc-2653	5	1	copyright	copyright	NOUN
dpc-2653	5	2	:	:	PUNCT
dpc-2653	5	3	©	©	PROPN
dpc-2653	5	4	2023	2023	NUM
dpc-2653	5	5	emvalomati	emvalomati	NOUN
dpc-2653	5	6	et	et	PROPN
dpc-2653	5	7	al	al	PROPN
dpc-2653	5	8	.	.	PUNCT
dpc-2653	6	1	this	this	PRON
dpc-2653	6	2	is	be	AUX
dpc-2653	6	3	an	an	DET
dpc-2653	6	4	open	open	ADJ
dpc-2653	6	5	-	-	PUNCT
dpc-2653	6	6	access	access	NOUN
dpc-2653	6	7	article	article	NOUN
dpc-2653	6	8	distributed	distribute	VERB
dpc-2653	6	9	under	under	ADP
dpc-2653	6	10	the	the	DET
dpc-2653	6	11	terms	term	NOUN
dpc-2653	6	12	of	of	ADP
dpc-2653	6	13	the	the	DET
dpc-2653	6	14	creative	creative	ADJ
dpc-2653	6	15	commons	common	NOUN
dpc-2653	6	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-2653	6	17	license	license	NOUN
dpc-2653	6	18	(	(	PUNCT
dpc-2653	6	19	by	by	ADP
dpc-2653	6	20	-	-	PUNCT
dpc-2653	6	21	nc-4.0	nc-4.0	NOUN
dpc-2653	6	22	)	)	PUNCT
dpc-2653	6	23	,	,	PUNCT
dpc-2653	6	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-2653	6	25	,	,	PUNCT
dpc-2653	6	26	which	which	PRON
dpc-2653	6	27	permits	permit	VERB
dpc-2653	6	28	unrestricted	unrestricted	ADJ
dpc-2653	6	29	noncommercial	noncommercial	ADJ
dpc-2653	6	30	use	use	NOUN
dpc-2653	6	31	,	,	PUNCT
dpc-2653	6	32	distribution	distribution	NOUN
dpc-2653	6	33	,	,	PUNCT
dpc-2653	6	34	and	and	CCONJ
dpc-2653	6	35	reproduction	reproduction	NOUN
dpc-2653	6	36	in	in	ADP
dpc-2653	6	37	any	any	DET
dpc-2653	6	38	medium	medium	NOUN
dpc-2653	6	39	,	,	PUNCT
dpc-2653	6	40	provided	provide	VERB
dpc-2653	6	41	the	the	DET
dpc-2653	6	42	original	original	ADJ
dpc-2653	6	43	authors	author	NOUN
dpc-2653	6	44	and	and	CCONJ
dpc-2653	6	45	source	source	NOUN
dpc-2653	6	46	are	be	AUX
dpc-2653	6	47	credited	credit	VERB
dpc-2653	6	48	.	.	PUNCT
dpc-2653	7	1	funding	funding	NOUN
dpc-2653	7	2	:	:	PUNCT
dpc-2653	7	3	none	none	NOUN
dpc-2653	7	4	.	.	PUNCT
dpc-2653	8	1	competing	compete	VERB
dpc-2653	8	2	interests	interest	NOUN
dpc-2653	8	3	:	:	PUNCT
dpc-2653	8	4	none	none	NOUN
dpc-2653	8	5	.	.	PUNCT
dpc-2653	9	1	authorship	authorship	NOUN
dpc-2653	9	2	:	:	PUNCT
dpc-2653	9	3	z.	z.	PROPN
dpc-2653	9	4	apalla	apalla	PROPN
dpc-2653	9	5	and	and	CCONJ
dpc-2653	9	6	m.	m.	NOUN
dpc-2653	9	7	trakatelli	trakatelli	PROPN
dpc-2653	9	8	equally	equally	ADV
dpc-2653	9	9	contributed	contribute	VERB
dpc-2653	9	10	as	as	ADP
dpc-2653	9	11	senior	senior	ADJ
dpc-2653	9	12	authors	author	NOUN
dpc-2653	9	13	.	.	PUNCT
dpc-2653	10	1	corresponding	correspond	VERB
dpc-2653	10	2	author	author	NOUN
dpc-2653	10	3	:	:	PUNCT
dpc-2653	10	4	myrto	myrto	PROPN
dpc-2653	10	5	trakatelli	trakatelli	PROPN
dpc-2653	10	6	,	,	PUNCT
dpc-2653	10	7	phd	phd	NOUN
dpc-2653	10	8	,	,	PUNCT
dpc-2653	10	9	second	second	ADJ
dpc-2653	10	10	dermatology	dermatology	NOUN
dpc-2653	10	11	department	department	NOUN
dpc-2653	10	12	,	,	PUNCT
dpc-2653	10	13	aristotle	aristotle	PROPN
dpc-2653	10	14	university	university	PROPN
dpc-2653	10	15	,	,	PUNCT
dpc-2653	10	16	76	76	NUM
dpc-2653	10	17	agiou	agiou	NOUN
dpc-2653	10	18	pavlou	pavlou	NOUN
dpc-2653	10	19	,	,	PUNCT
dpc-2653	10	20	pavlos	pavlos	PROPN
dpc-2653	10	21	melas	mela	NOUN
dpc-2653	10	22	,	,	PUNCT
dpc-2653	10	23	564	564	NUM
dpc-2653	10	24	29	29	NUM
dpc-2653	10	25	,	,	PUNCT
dpc-2653	10	26	thessaloniki	thessaloniki	PROPN
dpc-2653	10	27	,	,	PUNCT
dpc-2653	10	28	greece	greece	PROPN
dpc-2653	10	29	.	.	PUNCT
dpc-2653	11	1	tel	tel	PROPN
dpc-2653	11	2	.	.	PROPN
dpc-2653	11	3	+302313323873	+302313323873	PROPN
dpc-2653	11	4	,	,	PUNCT
dpc-2653	11	5	fax	fax	NOUN
dpc-2653	11	6	:	:	PUNCT
dpc-2653	11	7	+302310991473	+302310991473	NUM
dpc-2653	11	8	e	e	NOUN
dpc-2653	11	9	-	-	NOUN
dpc-2653	11	10	mail	mail	NOUN
dpc-2653	11	11	:	:	PUNCT
dpc-2653	12	1	mtrakatelli@hotmail.com	mtrakatelli@hotmail.com	X
dpc-2653	12	2	introduction	introduction	NOUN
dpc-2653	12	3	:	:	PUNCT
dpc-2653	12	4	nail	nail	NOUN
dpc-2653	12	5	toxicity	toxicity	NOUN
dpc-2653	12	6	represents	represent	VERB
dpc-2653	12	7	one	one	NUM
dpc-2653	12	8	of	of	ADP
dpc-2653	12	9	the	the	DET
dpc-2653	12	10	most	most	ADV
dpc-2653	12	11	common	common	ADJ
dpc-2653	12	12	cutaneous	cutaneous	ADJ
dpc-2653	12	13	adverse	adverse	ADJ
dpc-2653	12	14	effects	effect	NOUN
dpc-2653	12	15	of	of	ADP
dpc-2653	12	16	both	both	PRON
dpc-2653	12	17	classic	classic	ADJ
dpc-2653	12	18	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	12	19	agents	agent	NOUN
dpc-2653	12	20	and	and	CCONJ
dpc-2653	12	21	new	new	ADJ
dpc-2653	12	22	oncologic	oncologic	ADJ
dpc-2653	12	23	drugs	drug	NOUN
dpc-2653	12	24	,	,	PUNCT
dpc-2653	12	25	including	include	VERB
dpc-2653	12	26	targeted	target	VERB
dpc-2653	12	27	treatments	treatment	NOUN
dpc-2653	12	28	and	and	CCONJ
dpc-2653	12	29	immunotherapy	immunotherapy	NOUN
dpc-2653	12	30	.	.	PUNCT
dpc-2653	13	1	objectives	objective	NOUN
dpc-2653	13	2	:	:	PUNCT
dpc-2653	13	3	we	we	PRON
dpc-2653	13	4	aimed	aim	VERB
dpc-2653	13	5	to	to	PART
dpc-2653	13	6	provide	provide	VERB
dpc-2653	13	7	a	a	DET
dpc-2653	13	8	comprehensive	comprehensive	ADJ
dpc-2653	13	9	literature	literature	NOUN
dpc-2653	13	10	review	review	NOUN
dpc-2653	13	11	of	of	ADP
dpc-2653	13	12	nail	nail	NOUN
dpc-2653	13	13	toxicities	toxicity	NOUN
dpc-2653	13	14	derived	derive	VERB
dpc-2653	13	15	from	from	ADP
dpc-2653	13	16	conventional	conventional	ADJ
dpc-2653	13	17	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	13	18	agents	agent	NOUN
dpc-2653	13	19	,	,	PUNCT
dpc-2653	13	20	targeted	target	VERB
dpc-2653	13	21	therapies	therapy	NOUN
dpc-2653	13	22	(	(	PUNCT
dpc-2653	13	23	egfr	egfr	ADJ
dpc-2653	13	24	inhibitors	inhibitor	NOUN
dpc-2653	13	25	,	,	PUNCT
dpc-2653	13	26	multikinase	multikinase	VERB
dpc-2653	13	27	inhibitors	inhibitor	NOUN
dpc-2653	13	28	,	,	PUNCT
dpc-2653	13	29	braf	braf	NOUN
dpc-2653	13	30	and	and	CCONJ
dpc-2653	13	31	mek	mek	PROPN
dpc-2653	13	32	inhibitors	inhibitor	NOUN
dpc-2653	13	33	)	)	PUNCT
dpc-2653	13	34	and	and	CCONJ
dpc-2653	13	35	immune	immune	ADJ
dpc-2653	13	36	checkpoint	checkpoint	NOUN
dpc-2653	13	37	inhibitors	inhibitor	NOUN
dpc-2653	13	38	(	(	PUNCT
dpc-2653	13	39	icis	icis	NOUN
dpc-2653	13	40	)	)	PUNCT
dpc-2653	13	41	,	,	PUNCT
dpc-2653	13	42	including	include	VERB
dpc-2653	13	43	clinical	clinical	ADJ
dpc-2653	13	44	presentation	presentation	NOUN
dpc-2653	13	45	,	,	PUNCT
dpc-2653	13	46	implicated	implicate	VERB
dpc-2653	13	47	drugs	drug	NOUN
dpc-2653	13	48	and	and	CCONJ
dpc-2653	13	49	approaches	approach	NOUN
dpc-2653	13	50	for	for	ADP
dpc-2653	13	51	prevention	prevention	NOUN
dpc-2653	13	52	and	and	CCONJ
dpc-2653	13	53	management	management	NOUN
dpc-2653	13	54	.	.	PUNCT
dpc-2653	14	1	methods	method	NOUN
dpc-2653	14	2	:	:	PUNCT
dpc-2653	14	3	retrieved	retrieve	VERB
dpc-2653	14	4	literature	literature	NOUN
dpc-2653	14	5	from	from	ADP
dpc-2653	14	6	pubmed	pubmed	PROPN
dpc-2653	14	7	registry	registry	PROPN
dpc-2653	14	8	database	database	PROPN
dpc-2653	14	9	was	be	AUX
dpc-2653	14	10	reviewed	review	VERB
dpc-2653	14	11	to	to	PART
dpc-2653	14	12	include	include	VERB
dpc-2653	14	13	all	all	DET
dpc-2653	14	14	articles	article	NOUN
dpc-2653	14	15	published	publish	VERB
dpc-2653	14	16	up	up	ADP
dpc-2653	14	17	to	to	ADP
dpc-2653	14	18	may	may	PROPN
dpc-2653	14	19	2021	2021	NUM
dpc-2653	14	20	relevant	relevant	ADJ
dpc-2653	14	21	to	to	ADP
dpc-2653	14	22	the	the	DET
dpc-2653	14	23	clinical	clinical	ADJ
dpc-2653	14	24	presentation	presentation	NOUN
dpc-2653	14	25	,	,	PUNCT
dpc-2653	14	26	diagnosis	diagnosis	NOUN
dpc-2653	14	27	,	,	PUNCT
dpc-2653	14	28	incidence	incidence	NOUN
dpc-2653	14	29	,	,	PUNCT
dpc-2653	14	30	prevention	prevention	NOUN
dpc-2653	14	31	,	,	PUNCT
dpc-2653	14	32	and	and	CCONJ
dpc-2653	14	33	treatment	treatment	NOUN
dpc-2653	14	34	of	of	ADP
dpc-2653	14	35	oncologic	oncologic	ADJ
dpc-2653	14	36	treatment	treatment	NOUN
dpc-2653	14	37	-	-	PUNCT
dpc-2653	14	38	induced	induce	VERB
dpc-2653	14	39	nail	nail	NOUN
dpc-2653	14	40	toxicity	toxicity	NOUN
dpc-2653	14	41	.	.	PUNCT
dpc-2653	15	1	the	the	DET
dpc-2653	15	2	internet	internet	NOUN
dpc-2653	15	3	was	be	AUX
dpc-2653	15	4	searched	search	VERB
dpc-2653	15	5	for	for	ADP
dpc-2653	15	6	relevant	relevant	ADJ
dpc-2653	15	7	studies	study	NOUN
dpc-2653	15	8	.	.	PUNCT
dpc-2653	16	1	results	result	NOUN
dpc-2653	16	2	:	:	PUNCT
dpc-2653	16	3	a	a	DET
dpc-2653	16	4	wide	wide	ADJ
dpc-2653	16	5	spectrum	spectrum	NOUN
dpc-2653	16	6	of	of	ADP
dpc-2653	16	7	nail	nail	NOUN
dpc-2653	16	8	toxicities	toxicity	NOUN
dpc-2653	16	9	is	be	AUX
dpc-2653	16	10	associated	associate	VERB
dpc-2653	16	11	with	with	ADP
dpc-2653	16	12	both	both	PRON
dpc-2653	16	13	,	,	PUNCT
dpc-2653	16	14	conventional	conventional	ADJ
dpc-2653	16	15	and	and	CCONJ
dpc-2653	16	16	newer	new	ADJ
dpc-2653	16	17	anticancer	anticancer	NOUN
dpc-2653	16	18	agents	agent	NOUN
dpc-2653	16	19	.	.	PUNCT
dpc-2653	17	1	the	the	DET
dpc-2653	17	2	frequency	frequency	NOUN
dpc-2653	17	3	of	of	ADP
dpc-2653	17	4	nail	nail	NOUN
dpc-2653	17	5	involvement	involvement	NOUN
dpc-2653	17	6	,	,	PUNCT
dpc-2653	17	7	especially	especially	ADV
dpc-2653	17	8	with	with	ADP
dpc-2653	17	9	immunotherapy	immunotherapy	NOUN
dpc-2653	17	10	and	and	CCONJ
dpc-2653	17	11	new	new	ADJ
dpc-2653	17	12	targeted	target	VERB
dpc-2653	17	13	agents	agent	NOUN
dpc-2653	17	14	remains	remain	VERB
dpc-2653	17	15	unknown	unknown	ADJ
dpc-2653	17	16	and	and	CCONJ
dpc-2653	17	17	patients	patient	NOUN
dpc-2653	17	18	with	with	ADP
dpc-2653	17	19	different	different	ADJ
dpc-2653	17	20	cancer	cancer	NOUN
dpc-2653	17	21	types	type	NOUN
dpc-2653	17	22	receiving	receive	VERB
dpc-2653	17	23	different	different	ADJ
dpc-2653	17	24	regimens	regimen	NOUN
dpc-2653	17	25	may	may	AUX
dpc-2653	17	26	develop	develop	VERB
dpc-2653	17	27	the	the	DET
dpc-2653	17	28	same	same	ADJ
dpc-2653	17	29	nail	nail	NOUN
dpc-2653	17	30	disorder	disorder	NOUN
dpc-2653	17	31	,	,	PUNCT
dpc-2653	17	32	whereas	whereas	SCONJ
dpc-2653	17	33	patients	patient	NOUN
dpc-2653	17	34	with	with	ADP
dpc-2653	17	35	the	the	DET
dpc-2653	17	36	same	same	ADJ
dpc-2653	17	37	type	type	NOUN
dpc-2653	17	38	of	of	ADP
dpc-2653	17	39	cancer	cancer	NOUN
dpc-2653	17	40	under	under	ADP
dpc-2653	17	41	the	the	DET
dpc-2653	17	42	same	same	ADJ
dpc-2653	17	43	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	17	44	treatment	treatment	NOUN
dpc-2653	17	45	may	may	AUX
dpc-2653	17	46	develop	develop	VERB
dpc-2653	17	47	different	different	ADJ
dpc-2653	17	48	types	type	NOUN
dpc-2653	17	49	of	of	ADP
dpc-2653	17	50	nail	nail	NOUN
dpc-2653	17	51	alterations	alteration	NOUN
dpc-2653	17	52	.	.	PUNCT
dpc-2653	18	1	the	the	DET
dpc-2653	18	2	underlying	underlie	VERB
dpc-2653	18	3	mechanisms	mechanism	NOUN
dpc-2653	18	4	of	of	ADP
dpc-2653	18	5	the	the	DET
dpc-2653	18	6	varying	vary	VERB
dpc-2653	18	7	individual	individual	ADJ
dpc-2653	18	8	susceptibility	susceptibility	NOUN
dpc-2653	18	9	and	and	CCONJ
dpc-2653	18	10	the	the	DET
dpc-2653	18	11	diverse	diverse	ADJ
dpc-2653	18	12	nail	nail	NOUN
dpc-2653	18	13	responses	response	NOUN
dpc-2653	18	14	to	to	ADP
dpc-2653	18	15	various	various	ADJ
dpc-2653	18	16	anticancer	anticancer	NOUN
dpc-2653	18	17	treatments	treatment	NOUN
dpc-2653	18	18	need	need	VERB
dpc-2653	18	19	further	further	ADJ
dpc-2653	18	20	investigation	investigation	NOUN
dpc-2653	18	21	.	.	PUNCT
dpc-2653	19	1	conclusion	conclusion	NOUN
dpc-2653	19	2	:	:	PUNCT
dpc-2653	19	3	early	early	ADJ
dpc-2653	19	4	recognition	recognition	NOUN
dpc-2653	19	5	and	and	CCONJ
dpc-2653	19	6	treatment	treatment	NOUN
dpc-2653	19	7	of	of	ADP
dpc-2653	19	8	nail	nail	NOUN
dpc-2653	19	9	toxicities	toxicity	NOUN
dpc-2653	19	10	can	can	AUX
dpc-2653	19	11	minimize	minimize	VERB
dpc-2653	19	12	their	their	PRON
dpc-2653	19	13	impact	impact	NOUN
dpc-2653	19	14	,	,	PUNCT
dpc-2653	19	15	allowing	allow	VERB
dpc-2653	19	16	better	well	ADJ
dpc-2653	19	17	adherence	adherence	NOUN
dpc-2653	19	18	to	to	ADP
dpc-2653	19	19	conventional	conventional	ADJ
dpc-2653	19	20	and	and	CCONJ
dpc-2653	19	21	newer	new	ADJ
dpc-2653	19	22	oncologic	oncologic	ADJ
dpc-2653	19	23	treatments	treatment	NOUN
dpc-2653	19	24	.	.	PUNCT
dpc-2653	20	1	dermatologists	dermatologist	NOUN
dpc-2653	20	2	,	,	PUNCT
dpc-2653	20	3	oncologists	oncologist	NOUN
dpc-2653	20	4	and	and	CCONJ
dpc-2653	20	5	other	other	ADJ
dpc-2653	20	6	implicated	implicated	ADJ
dpc-2653	20	7	physicians	physician	NOUN
dpc-2653	20	8	should	should	AUX
dpc-2653	20	9	be	be	AUX
dpc-2653	20	10	aware	aware	ADJ
dpc-2653	20	11	of	of	ADP
dpc-2653	20	12	these	these	DET
dpc-2653	20	13	burdensome	burdensome	ADJ
dpc-2653	20	14	adverse	adverse	ADJ
dpc-2653	20	15	effects	effect	NOUN
dpc-2653	20	16	in	in	ADP
dpc-2653	20	17	order	order	NOUN
dpc-2653	20	18	to	to	PART
dpc-2653	20	19	guide	guide	VERB
dpc-2653	20	20	management	management	NOUN
dpc-2653	20	21	and	and	CCONJ
dpc-2653	20	22	prevent	prevent	VERB
dpc-2653	20	23	impairment	impairment	NOUN
dpc-2653	20	24	of	of	ADP
dpc-2653	20	25	patients	patient	NOUN
dpc-2653	20	26	’	'	PUNCT
dpc-2653	20	27	quality	quality	NOUN
dpc-2653	20	28	of	of	ADP
dpc-2653	20	29	life	life	NOUN
dpc-2653	20	30	.	.	PUNCT
dpc-2653	21	1	abstract	abstract	ADJ
dpc-2653	21	2	2	2	NUM
dpc-2653	21	3	review	review	NOUN
dpc-2653	21	4	|	|	ADV
dpc-2653	21	5	dermatol	dermatol	ADJ
dpc-2653	21	6	pract	pract	NOUN
dpc-2653	21	7	concept	concept	NOUN
dpc-2653	21	8	.	.	PUNCT
dpc-2653	22	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	22	2	introduction	introduction	NOUN
dpc-2653	22	3	nail	nail	NOUN
dpc-2653	22	4	toxicity	toxicity	NOUN
dpc-2653	22	5	represents	represent	VERB
dpc-2653	22	6	one	one	NUM
dpc-2653	22	7	of	of	ADP
dpc-2653	22	8	the	the	DET
dpc-2653	22	9	most	most	ADV
dpc-2653	22	10	common	common	ADJ
dpc-2653	22	11	cutaneous	cutaneous	ADJ
dpc-2653	22	12	adverse	adverse	ADJ
dpc-2653	22	13	effects	effect	NOUN
dpc-2653	22	14	of	of	ADP
dpc-2653	22	15	both	both	PRON
dpc-2653	22	16	classic	classic	ADJ
dpc-2653	22	17	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	22	18	agents	agent	NOUN
dpc-2653	22	19	and	and	CCONJ
dpc-2653	22	20	new	new	ADJ
dpc-2653	22	21	oncologic	oncologic	ADJ
dpc-2653	22	22	drugs	drug	NOUN
dpc-2653	22	23	,	,	PUNCT
dpc-2653	22	24	including	include	VERB
dpc-2653	22	25	targeted	target	VERB
dpc-2653	22	26	treatments	treatment	NOUN
dpc-2653	22	27	and	and	CCONJ
dpc-2653	22	28	immunotherapy	immunotherapy	NOUN
dpc-2653	23	1	[	[	X
dpc-2653	23	2	1	1	NUM
dpc-2653	23	3	]	]	PUNCT
dpc-2653	23	4	.	.	PUNCT
dpc-2653	24	1	while	while	SCONJ
dpc-2653	24	2	drug	drug	NOUN
dpc-2653	24	3	-	-	PUNCT
dpc-2653	24	4	associated	associate	VERB
dpc-2653	24	5	nail	nail	NOUN
dpc-2653	24	6	toxicity	toxicity	NOUN
dpc-2653	24	7	is	be	AUX
dpc-2653	24	8	almost	almost	ADV
dpc-2653	24	9	never	never	ADV
dpc-2653	24	10	life	life	NOUN
dpc-2653	24	11	-	-	PUNCT
dpc-2653	24	12	threatening	threaten	VERB
dpc-2653	24	13	,	,	PUNCT
dpc-2653	24	14	it	it	PRON
dpc-2653	24	15	significantly	significantly	ADV
dpc-2653	24	16	impairs	impair	VERB
dpc-2653	24	17	patients	patient	NOUN
dpc-2653	24	18	’	'	PUNCT
dpc-2653	24	19	quality	quality	NOUN
dpc-2653	24	20	of	of	ADP
dpc-2653	24	21	life	life	NOUN
dpc-2653	24	22	,	,	PUNCT
dpc-2653	24	23	often	often	ADV
dpc-2653	24	24	restricting	restrict	VERB
dpc-2653	24	25	their	their	PRON
dpc-2653	24	26	daily	daily	ADJ
dpc-2653	24	27	life	life	NOUN
dpc-2653	24	28	and	and	CCONJ
dpc-2653	24	29	self	self	NOUN
dpc-2653	24	30	-	-	PUNCT
dpc-2653	24	31	care	care	NOUN
dpc-2653	24	32	activities	activity	NOUN
dpc-2653	24	33	.	.	PUNCT
dpc-2653	25	1	dermatologists	dermatologist	NOUN
dpc-2653	25	2	,	,	PUNCT
dpc-2653	25	3	oncologists	oncologist	NOUN
dpc-2653	25	4	and	and	CCONJ
dpc-2653	25	5	other	other	ADJ
dpc-2653	25	6	implicated	implicated	ADJ
dpc-2653	25	7	physicians	physician	NOUN
dpc-2653	25	8	should	should	AUX
dpc-2653	25	9	be	be	AUX
dpc-2653	25	10	aware	aware	ADJ
dpc-2653	25	11	of	of	ADP
dpc-2653	25	12	these	these	DET
dpc-2653	25	13	burdensome	burdensome	ADJ
dpc-2653	25	14	adverse	adverse	ADJ
dpc-2653	25	15	effects	effect	NOUN
dpc-2653	25	16	in	in	ADP
dpc-2653	25	17	order	order	NOUN
dpc-2653	25	18	to	to	PART
dpc-2653	25	19	guide	guide	VERB
dpc-2653	25	20	management	management	NOUN
dpc-2653	25	21	and	and	CCONJ
dpc-2653	25	22	prevent	prevent	VERB
dpc-2653	25	23	impairment	impairment	NOUN
dpc-2653	25	24	of	of	ADP
dpc-2653	25	25	patients	patient	NOUN
dpc-2653	25	26	’	'	PUNCT
dpc-2653	25	27	quality	quality	NOUN
dpc-2653	25	28	of	of	ADP
dpc-2653	25	29	life	life	NOUN
dpc-2653	25	30	.	.	PUNCT
dpc-2653	26	1	early	early	ADJ
dpc-2653	26	2	recognition	recognition	NOUN
dpc-2653	26	3	and	and	CCONJ
dpc-2653	26	4	treatment	treatment	NOUN
dpc-2653	26	5	can	can	AUX
dpc-2653	26	6	minimize	minimize	VERB
dpc-2653	26	7	the	the	DET
dpc-2653	26	8	impact	impact	NOUN
dpc-2653	26	9	of	of	ADP
dpc-2653	26	10	these	these	DET
dpc-2653	26	11	toxicities	toxicity	NOUN
dpc-2653	26	12	,	,	PUNCT
dpc-2653	26	13	allowing	allow	VERB
dpc-2653	26	14	better	well	ADJ
dpc-2653	26	15	adherence	adherence	NOUN
dpc-2653	26	16	to	to	ADP
dpc-2653	26	17	conventional	conventional	ADJ
dpc-2653	26	18	and	and	CCONJ
dpc-2653	26	19	newer	new	ADJ
dpc-2653	26	20	oncologic	oncologic	ADJ
dpc-2653	26	21	treatments	treatment	NOUN
dpc-2653	26	22	.	.	PUNCT
dpc-2653	27	1	the	the	DET
dpc-2653	27	2	aim	aim	NOUN
dpc-2653	27	3	of	of	ADP
dpc-2653	27	4	this	this	DET
dpc-2653	27	5	article	article	NOUN
dpc-2653	27	6	is	be	AUX
dpc-2653	27	7	to	to	PART
dpc-2653	27	8	provide	provide	VERB
dpc-2653	27	9	a	a	DET
dpc-2653	27	10	comprehensive	comprehensive	ADJ
dpc-2653	27	11	literature	literature	NOUN
dpc-2653	27	12	review	review	NOUN
dpc-2653	27	13	of	of	ADP
dpc-2653	27	14	nail	nail	NOUN
dpc-2653	27	15	toxicities	toxicity	NOUN
dpc-2653	27	16	derived	derive	VERB
dpc-2653	27	17	from	from	ADP
dpc-2653	27	18	conventional	conventional	ADJ
dpc-2653	27	19	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	27	20	agents	agent	NOUN
dpc-2653	27	21	,	,	PUNCT
dpc-2653	27	22	targeted	target	VERB
dpc-2653	27	23	therapies	therapy	NOUN
dpc-2653	27	24	(	(	PUNCT
dpc-2653	27	25	egfr	egfr	ADJ
dpc-2653	27	26	inhibitors	inhibitor	NOUN
dpc-2653	27	27	,	,	PUNCT
dpc-2653	27	28	multikinase	multikinase	VERB
dpc-2653	27	29	inhibitors	inhibitor	NOUN
dpc-2653	27	30	,	,	PUNCT
dpc-2653	27	31	braf	braf	NOUN
dpc-2653	27	32	and	and	CCONJ
dpc-2653	27	33	mek	mek	PROPN
dpc-2653	27	34	inhibitors	inhibitor	NOUN
dpc-2653	27	35	)	)	PUNCT
dpc-2653	27	36	and	and	CCONJ
dpc-2653	27	37	immune	immune	ADJ
dpc-2653	27	38	checkpoint	checkpoint	NOUN
dpc-2653	27	39	inhibitors	inhibitor	NOUN
dpc-2653	27	40	(	(	PUNCT
dpc-2653	27	41	icis	icis	NOUN
dpc-2653	27	42	)	)	PUNCT
dpc-2653	27	43	,	,	PUNCT
dpc-2653	27	44	including	include	VERB
dpc-2653	27	45	clinical	clinical	ADJ
dpc-2653	27	46	presentation	presentation	NOUN
dpc-2653	27	47	,	,	PUNCT
dpc-2653	27	48	implicated	implicate	VERB
dpc-2653	27	49	drugs	drug	NOUN
dpc-2653	27	50	and	and	CCONJ
dpc-2653	27	51	approaches	approach	NOUN
dpc-2653	27	52	for	for	ADP
dpc-2653	27	53	prevention	prevention	NOUN
dpc-2653	27	54	and	and	CCONJ
dpc-2653	27	55	 	 	SPACE
dpc-2653	27	56	management	management	NOUN
dpc-2653	27	57	.	.	PUNCT
dpc-2653	28	1	materials	material	NOUN
dpc-2653	28	2	and	and	CCONJ
dpc-2653	28	3	methods	method	NOUN
dpc-2653	28	4	search	search	NOUN
dpc-2653	28	5	strategy	strategy	NOUN
dpc-2653	28	6	and	and	CCONJ
dpc-2653	28	7	study	study	NOUN
dpc-2653	28	8	selection	selection	NOUN
dpc-2653	28	9	the	the	DET
dpc-2653	28	10	retrieved	retrieve	VERB
dpc-2653	28	11	literature	literature	NOUN
dpc-2653	28	12	was	be	AUX
dpc-2653	28	13	reviewed	review	VERB
dpc-2653	28	14	to	to	PART
dpc-2653	28	15	include	include	VERB
dpc-2653	28	16	all	all	DET
dpc-2653	28	17	articles	article	NOUN
dpc-2653	28	18	relevant	relevant	ADJ
dpc-2653	28	19	to	to	ADP
dpc-2653	28	20	the	the	DET
dpc-2653	28	21	clinical	clinical	ADJ
dpc-2653	28	22	presentation	presentation	NOUN
dpc-2653	28	23	,	,	PUNCT
dpc-2653	28	24	diagnosis	diagnosis	NOUN
dpc-2653	28	25	,	,	PUNCT
dpc-2653	28	26	incidence	incidence	NOUN
dpc-2653	28	27	,	,	PUNCT
dpc-2653	28	28	prevention	prevention	NOUN
dpc-2653	28	29	,	,	PUNCT
dpc-2653	28	30	and	and	CCONJ
dpc-2653	28	31	treatment	treatment	NOUN
dpc-2653	28	32	of	of	ADP
dpc-2653	28	33	oncologic	oncologic	ADJ
dpc-2653	28	34	treatment	treatment	NOUN
dpc-2653	28	35	-	-	PUNCT
dpc-2653	28	36	induced	induce	VERB
dpc-2653	28	37	nail	nail	NOUN
dpc-2653	28	38	toxicity	toxicity	NOUN
dpc-2653	28	39	.	.	PUNCT
dpc-2653	29	1	the	the	DET
dpc-2653	29	2	pubmed	pubmed	PROPN
dpc-2653	29	3	registry	registry	PROPN
dpc-2653	29	4	database	database	PROPN
dpc-2653	29	5	was	be	AUX
dpc-2653	29	6	searched	search	VERB
dpc-2653	29	7	for	for	ADP
dpc-2653	29	8	relevant	relevant	ADJ
dpc-2653	29	9	studies	study	NOUN
dpc-2653	29	10	published	publish	VERB
dpc-2653	29	11	up	up	ADP
dpc-2653	29	12	to	to	PART
dpc-2653	29	13	may	may	PROPN
dpc-2653	29	14	2021	2021	NUM
dpc-2653	29	15	.	.	PUNCT
dpc-2653	30	1	the	the	DET
dpc-2653	30	2	literature	literature	NOUN
dpc-2653	30	3	evidence	evidence	NOUN
dpc-2653	30	4	predominantly	predominantly	ADV
dpc-2653	30	5	comprises	comprise	VERB
dpc-2653	30	6	case	case	NOUN
dpc-2653	30	7	reports	report	NOUN
dpc-2653	30	8	,	,	PUNCT
dpc-2653	30	9	case	case	NOUN
dpc-2653	30	10	series	series	NOUN
dpc-2653	30	11	and	and	CCONJ
dpc-2653	30	12	systematic	systematic	ADJ
dpc-2653	30	13	reviews	review	NOUN
dpc-2653	30	14	.	.	PUNCT
dpc-2653	31	1	the	the	DET
dpc-2653	31	2	following	follow	VERB
dpc-2653	31	3	medical	medical	ADJ
dpc-2653	31	4	subject	subject	NOUN
dpc-2653	31	5	headings	heading	NOUN
dpc-2653	31	6	search	search	NOUN
dpc-2653	31	7	terms	term	NOUN
dpc-2653	31	8	were	be	AUX
dpc-2653	31	9	used	use	VERB
dpc-2653	31	10	:	:	PUNCT
dpc-2653	31	11	nails	nail	NOUN
dpc-2653	31	12	,	,	PUNCT
dpc-2653	31	13	nail	nail	NOUN
dpc-2653	31	14	changes	change	NOUN
dpc-2653	31	15	,	,	PUNCT
dpc-2653	31	16	nail	nail	NOUN
dpc-2653	31	17	toxicity	toxicity	NOUN
dpc-2653	31	18	;	;	PUNCT
dpc-2653	31	19	chemotherapy	chemotherapy	NOUN
dpc-2653	31	20	,	,	PUNCT
dpc-2653	31	21	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	31	22	drugs	drug	NOUN
dpc-2653	31	23	/	/	SYM
dpc-2653	31	24	agents	agent	NOUN
dpc-2653	31	25	,	,	PUNCT
dpc-2653	31	26	antineoplastic	antineoplastic	ADJ
dpc-2653	31	27	agents	agent	NOUN
dpc-2653	31	28	.	.	PUNCT
dpc-2653	32	1	the	the	DET
dpc-2653	32	2	“	"	PUNCT
dpc-2653	32	3	related	related	ADJ
dpc-2653	32	4	articles	article	NOUN
dpc-2653	32	5	”	"	PUNCT
dpc-2653	32	6	function	function	NOUN
dpc-2653	32	7	in	in	ADP
dpc-2653	32	8	pubmed	pubmed	PROPN
dpc-2653	32	9	was	be	AUX
dpc-2653	32	10	used	use	VERB
dpc-2653	32	11	to	to	PART
dpc-2653	32	12	broaden	broaden	VERB
dpc-2653	32	13	the	the	DET
dpc-2653	32	14	search	search	NOUN
dpc-2653	32	15	,	,	PUNCT
dpc-2653	32	16	and	and	CCONJ
dpc-2653	32	17	all	all	DET
dpc-2653	32	18	retrieved	retrieve	VERB
dpc-2653	32	19	abstracts	abstract	NOUN
dpc-2653	32	20	,	,	PUNCT
dpc-2653	32	21	studies	study	NOUN
dpc-2653	32	22	and	and	CCONJ
dpc-2653	32	23	citations	citation	NOUN
dpc-2653	32	24	were	be	AUX
dpc-2653	32	25	reviewed	review	VERB
dpc-2653	32	26	.	.	PUNCT
dpc-2653	33	1	in	in	ADP
dpc-2653	33	2	addition	addition	NOUN
dpc-2653	33	3	,	,	PUNCT
dpc-2653	33	4	we	we	PRON
dpc-2653	33	5	identified	identify	VERB
dpc-2653	33	6	other	other	ADJ
dpc-2653	33	7	relevant	relevant	ADJ
dpc-2653	33	8	studies	study	NOUN
dpc-2653	33	9	by	by	ADP
dpc-2653	33	10	searching	search	VERB
dpc-2653	33	11	the	the	DET
dpc-2653	33	12	reference	reference	NOUN
dpc-2653	33	13	lists	list	NOUN
dpc-2653	33	14	of	of	ADP
dpc-2653	33	15	the	the	DET
dpc-2653	33	16	relevant	relevant	ADJ
dpc-2653	33	17	articles	article	NOUN
dpc-2653	33	18	and	and	CCONJ
dpc-2653	33	19	by	by	ADP
dpc-2653	33	20	contacting	contact	VERB
dpc-2653	33	21	known	known	ADJ
dpc-2653	33	22	experts	expert	NOUN
dpc-2653	33	23	in	in	ADP
dpc-2653	33	24	the	the	DET
dpc-2653	33	25	field	field	NOUN
dpc-2653	33	26	.	.	PUNCT
dpc-2653	34	1	no	no	DET
dpc-2653	34	2	language	language	NOUN
dpc-2653	34	3	restrictions	restriction	NOUN
dpc-2653	34	4	were	be	AUX
dpc-2653	34	5	applied	apply	VERB
dpc-2653	34	6	.	.	PUNCT
dpc-2653	35	1	data	datum	NOUN
dpc-2653	35	2	extraction	extraction	NOUN
dpc-2653	35	3	two	two	NUM
dpc-2653	35	4	reviewers	reviewer	NOUN
dpc-2653	35	5	independently	independently	ADV
dpc-2653	35	6	assessed	assess	VERB
dpc-2653	35	7	all	all	DET
dpc-2653	35	8	relevant	relevant	ADJ
dpc-2653	35	9	studies	study	NOUN
dpc-2653	35	10	and	and	CCONJ
dpc-2653	35	11	specifically	specifically	ADV
dpc-2653	35	12	extracted	extract	VERB
dpc-2653	35	13	data	datum	NOUN
dpc-2653	35	14	regarding	regard	VERB
dpc-2653	35	15	study	study	NOUN
dpc-2653	35	16	design	design	NOUN
dpc-2653	35	17	,	,	PUNCT
dpc-2653	35	18	study	study	NOUN
dpc-2653	35	19	population	population	NOUN
dpc-2653	35	20	characteristics	characteristic	NOUN
dpc-2653	35	21	,	,	PUNCT
dpc-2653	35	22	inclusion	inclusion	NOUN
dpc-2653	35	23	and	and	CCONJ
dpc-2653	35	24	exclusion	exclusion	NOUN
dpc-2653	35	25	criteria	criterion	NOUN
dpc-2653	35	26	,	,	PUNCT
dpc-2653	35	27	nail	nail	NOUN
dpc-2653	35	28	toxicity	toxicity	NOUN
dpc-2653	35	29	parameters	parameter	NOUN
dpc-2653	35	30	,	,	PUNCT
dpc-2653	35	31	class	class	NOUN
dpc-2653	35	32	of	of	ADP
dpc-2653	35	33	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	35	34	drugs	drug	NOUN
dpc-2653	35	35	and	and	CCONJ
dpc-2653	35	36	their	their	PRON
dpc-2653	35	37	mechanism	mechanism	NOUN
dpc-2653	35	38	of	of	ADP
dpc-2653	35	39	action	action	NOUN
dpc-2653	35	40	.	.	PUNCT
dpc-2653	36	1	the	the	DET
dpc-2653	36	2	individually	individually	ADV
dpc-2653	36	3	recorded	record	VERB
dpc-2653	36	4	decisions	decision	NOUN
dpc-2653	36	5	of	of	ADP
dpc-2653	36	6	both	both	DET
dpc-2653	36	7	reviewers	reviewer	NOUN
dpc-2653	36	8	were	be	AUX
dpc-2653	36	9	compared	compare	VERB
dpc-2653	36	10	and	and	CCONJ
dpc-2653	36	11	any	any	DET
dpc-2653	36	12	disagreements	disagreement	NOUN
dpc-2653	36	13	were	be	AUX
dpc-2653	36	14	resolved	resolve	VERB
dpc-2653	36	15	by	by	ADP
dpc-2653	36	16	the	the	DET
dpc-2653	36	17	other	other	ADJ
dpc-2653	36	18	reviewers	reviewer	NOUN
dpc-2653	36	19	.	.	PUNCT
dpc-2653	37	1	study	study	NOUN
dpc-2653	37	2	authors	author	NOUN
dpc-2653	37	3	were	be	AUX
dpc-2653	37	4	contacted	contact	VERB
dpc-2653	37	5	for	for	ADP
dpc-2653	37	6	additional	additional	ADJ
dpc-2653	37	7	information	information	NOUN
dpc-2653	37	8	when	when	SCONJ
dpc-2653	37	9	necessary	necessary	ADJ
dpc-2653	37	10	.	.	PUNCT
dpc-2653	38	1	discussion	discussion	NOUN
dpc-2653	38	2	conventional	conventional	ADJ
dpc-2653	38	3	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	38	4	drugs	drug	NOUN
dpc-2653	38	5	(	(	PUNCT
dpc-2653	38	6	figure	figure	NOUN
dpc-2653	38	7	1	1	NUM
dpc-2653	38	8	)	)	PUNCT
dpc-2653	38	9	cancer	cancer	NOUN
dpc-2653	38	10	therapy	therapy	NOUN
dpc-2653	38	11	has	have	AUX
dpc-2653	38	12	always	always	ADV
dpc-2653	38	13	been	be	AUX
dpc-2653	38	14	a	a	DET
dpc-2653	38	15	challenging	challenging	ADJ
dpc-2653	38	16	area	area	NOUN
dpc-2653	38	17	in	in	ADP
dpc-2653	38	18	clinical	clinical	ADJ
dpc-2653	38	19	medicine	medicine	NOUN
dpc-2653	38	20	and	and	CCONJ
dpc-2653	38	21	research	research	NOUN
dpc-2653	38	22	.	.	PUNCT
dpc-2653	39	1	traditionally	traditionally	ADV
dpc-2653	39	2	,	,	PUNCT
dpc-2653	39	3	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	39	4	drugs	drug	NOUN
dpc-2653	39	5	work	work	VERB
dpc-2653	39	6	by	by	ADP
dpc-2653	39	7	disrupting	disrupt	VERB
dpc-2653	39	8	specific	specific	ADJ
dpc-2653	39	9	phases	phase	NOUN
dpc-2653	39	10	of	of	ADP
dpc-2653	39	11	the	the	DET
dpc-2653	39	12	cell	cell	NOUN
dpc-2653	39	13	cycle	cycle	NOUN
dpc-2653	39	14	in	in	ADP
dpc-2653	39	15	actively	actively	ADV
dpc-2653	39	16	dividing	divide	VERB
dpc-2653	39	17	cancer	cancer	NOUN
dpc-2653	39	18	cells	cell	NOUN
dpc-2653	39	19	(	(	PUNCT
dpc-2653	39	20	table	table	NOUN
dpc-2653	39	21	2	2	NUM
dpc-2653	39	22	)	)	PUNCT
dpc-2653	39	23	.	.	PUNCT
dpc-2653	40	1	conventional	conventional	ADJ
dpc-2653	40	2	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	40	3	drugs	drug	NOUN
dpc-2653	40	4	continue	continue	VERB
dpc-2653	40	5	to	to	PART
dpc-2653	40	6	be	be	AUX
dpc-2653	40	7	an	an	DET
dpc-2653	40	8	important	important	ADJ
dpc-2653	40	9	part	part	NOUN
dpc-2653	40	10	of	of	ADP
dpc-2653	40	11	cancer	cancer	NOUN
dpc-2653	40	12	management	management	NOUN
dpc-2653	40	13	but	but	CCONJ
dpc-2653	40	14	may	may	AUX
dpc-2653	40	15	cause	cause	VERB
dpc-2653	40	16	various	various	ADJ
dpc-2653	40	17	cutaneous	cutaneous	ADJ
dpc-2653	40	18	and	and	CCONJ
dpc-2653	40	19	appendageal	appendageal	ADJ
dpc-2653	40	20	reactions	reaction	NOUN
dpc-2653	40	21	including	include	VERB
dpc-2653	40	22	nail	nail	NOUN
dpc-2653	40	23	toxicity	toxicity	NOUN
dpc-2653	40	24	.	.	PUNCT
dpc-2653	41	1	nail	nail	NOUN
dpc-2653	41	2	involvement	involvement	NOUN
dpc-2653	41	3	in	in	ADP
dpc-2653	41	4	cancer	cancer	NOUN
dpc-2653	41	5	therapy	therapy	NOUN
dpc-2653	41	6	is	be	AUX
dpc-2653	41	7	reported	report	VERB
dpc-2653	41	8	in	in	ADP
dpc-2653	41	9	fragmented	fragmented	ADJ
dpc-2653	41	10	literature	literature	NOUN
dpc-2653	41	11	from	from	ADP
dpc-2653	41	12	all	all	ADV
dpc-2653	41	13	over	over	ADP
dpc-2653	41	14	the	the	DET
dpc-2653	41	15	world	world	NOUN
dpc-2653	41	16	.	.	PUNCT
dpc-2653	42	1	although	although	SCONJ
dpc-2653	42	2	it	it	PRON
dpc-2653	42	3	is	be	AUX
dpc-2653	42	4	mostly	mostly	ADV
dpc-2653	42	5	of	of	ADP
dpc-2653	42	6	cosmetic	cosmetic	ADJ
dpc-2653	42	7	concern	concern	NOUN
dpc-2653	42	8	,	,	PUNCT
dpc-2653	42	9	at	at	ADP
dpc-2653	42	10	times	time	NOUN
dpc-2653	42	11	it	it	PRON
dpc-2653	42	12	may	may	AUX
dpc-2653	42	13	require	require	VERB
dpc-2653	42	14	alteration	alteration	NOUN
dpc-2653	42	15	or	or	CCONJ
dpc-2653	42	16	modification	modification	NOUN
dpc-2653	42	17	of	of	ADP
dpc-2653	42	18	the	the	DET
dpc-2653	42	19	therapy	therapy	NOUN
dpc-2653	42	20	,	,	PUNCT
dpc-2653	42	21	especially	especially	ADV
dpc-2653	42	22	if	if	SCONJ
dpc-2653	42	23	very	very	ADV
dpc-2653	42	24	painful	painful	ADJ
dpc-2653	42	25	or	or	CCONJ
dpc-2653	42	26	functionally	functionally	ADV
dpc-2653	42	27	debilitating	debilitate	VERB
dpc-2653	42	28	nail	nail	NOUN
dpc-2653	42	29	toxic	toxic	ADJ
dpc-2653	42	30	effects	effect	NOUN
dpc-2653	42	31	are	be	AUX
dpc-2653	42	32	present	present	ADJ
dpc-2653	42	33	.	.	PUNCT
dpc-2653	43	1	pain	pain	NOUN
dpc-2653	43	2	and	and	CCONJ
dpc-2653	43	3	associated	associated	ADJ
dpc-2653	43	4	discomfort	discomfort	NOUN
dpc-2653	43	5	impair	impair	NOUN
dpc-2653	43	6	patients	patient	NOUN
dpc-2653	43	7	’	'	PUNCT
dpc-2653	43	8	quality	quality	NOUN
dpc-2653	43	9	of	of	ADP
dpc-2653	43	10	life	life	NOUN
dpc-2653	43	11	,	,	PUNCT
dpc-2653	43	12	commonly	commonly	ADV
dpc-2653	43	13	resulting	result	VERB
dpc-2653	43	14	in	in	ADP
dpc-2653	43	15	the	the	DET
dpc-2653	43	16	inability	inability	NOUN
dpc-2653	43	17	to	to	PART
dpc-2653	43	18	perform	perform	VERB
dpc-2653	43	19	daily	daily	ADJ
dpc-2653	43	20	activities	activity	NOUN
dpc-2653	43	21	[	[	X
dpc-2653	43	22	2	2	NUM
dpc-2653	43	23	]	]	PUNCT
dpc-2653	43	24	.	.	PUNCT
dpc-2653	44	1	the	the	DET
dpc-2653	44	2	nail	nail	NOUN
dpc-2653	44	3	apparatus	apparatus	NOUN
dpc-2653	44	4	is	be	AUX
dpc-2653	44	5	characterized	characterize	VERB
dpc-2653	44	6	by	by	ADP
dpc-2653	44	7	the	the	DET
dpc-2653	44	8	presence	presence	NOUN
dpc-2653	44	9	of	of	ADP
dpc-2653	44	10	continuously	continuously	ADV
dpc-2653	44	11	dividing	divide	VERB
dpc-2653	44	12	nail	nail	NOUN
dpc-2653	44	13	matrix	matrix	NOUN
dpc-2653	44	14	cells	cell	NOUN
dpc-2653	44	15	,	,	PUNCT
dpc-2653	44	16	thus	thus	ADV
dpc-2653	44	17	making	make	VERB
dpc-2653	44	18	it	it	PRON
dpc-2653	44	19	an	an	DET
dpc-2653	44	20	easy	easy	ADJ
dpc-2653	44	21	target	target	NOUN
dpc-2653	44	22	of	of	ADP
dpc-2653	44	23	the	the	DET
dpc-2653	44	24	antimitotic	antimitotic	ADJ
dpc-2653	44	25	activity	activity	NOUN
dpc-2653	44	26	of	of	ADP
dpc-2653	44	27	chemotherapeutics	chemotherapeutic	NOUN
dpc-2653	45	1	[	[	X
dpc-2653	45	2	3	3	NUM
dpc-2653	45	3	]	]	PUNCT
dpc-2653	45	4	.	.	PUNCT
dpc-2653	46	1	nail	nail	NOUN
dpc-2653	46	2	changes	change	NOUN
dpc-2653	46	3	in	in	ADP
dpc-2653	46	4	the	the	DET
dpc-2653	46	5	context	context	NOUN
dpc-2653	46	6	of	of	ADP
dpc-2653	46	7	chemotherapy	chemotherapy	NOUN
dpc-2653	46	8	involve	involve	VERB
dpc-2653	46	9	multiple	multiple	ADJ
dpc-2653	46	10	or	or	CCONJ
dpc-2653	46	11	even	even	ADV
dpc-2653	46	12	all	all	DET
dpc-2653	46	13	20	20	NUM
dpc-2653	46	14	nails	nail	NOUN
dpc-2653	46	15	and	and	CCONJ
dpc-2653	46	16	usually	usually	ADV
dpc-2653	46	17	appear	appear	VERB
dpc-2653	46	18	in	in	ADP
dpc-2653	46	19	a	a	DET
dpc-2653	46	20	temporal	temporal	ADJ
dpc-2653	46	21	relation	relation	NOUN
dpc-2653	46	22	with	with	ADP
dpc-2653	46	23	the	the	DET
dpc-2653	46	24	drug	drug	NOUN
dpc-2653	46	25	intake	intake	NOUN
dpc-2653	46	26	,	,	PUNCT
dpc-2653	46	27	due	due	ADP
dpc-2653	46	28	to	to	ADP
dpc-2653	46	29	an	an	DET
dpc-2653	46	30	acute	acute	ADJ
dpc-2653	46	31	insult	insult	NOUN
dpc-2653	46	32	of	of	ADP
dpc-2653	46	33	the	the	DET
dpc-2653	46	34	nail	nail	NOUN
dpc-2653	46	35	matrix	matrix	NOUN
dpc-2653	46	36	epithelium	epithelium	NOUN
dpc-2653	46	37	.	.	PUNCT
dpc-2653	47	1	effects	effect	NOUN
dpc-2653	47	2	mostly	mostly	ADV
dpc-2653	47	3	subside	subside	VERB
dpc-2653	47	4	upon	upon	SCONJ
dpc-2653	47	5	withdrawal	withdrawal	NOUN
dpc-2653	47	6	of	of	ADP
dpc-2653	47	7	the	the	DET
dpc-2653	47	8	responsible	responsible	ADJ
dpc-2653	47	9	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	47	10	agent	agent	NOUN
dpc-2653	47	11	,	,	PUNCT
dpc-2653	47	12	but	but	CCONJ
dpc-2653	47	13	occasionally	occasionally	ADV
dpc-2653	47	14	may	may	AUX
dpc-2653	47	15	persist	persist	VERB
dpc-2653	47	16	.	.	PUNCT
dpc-2653	48	1	because	because	SCONJ
dpc-2653	48	2	of	of	ADP
dpc-2653	48	3	the	the	DET
dpc-2653	48	4	specific	specific	ADJ
dpc-2653	48	5	kinetics	kinetic	NOUN
dpc-2653	48	6	of	of	ADP
dpc-2653	48	7	nail	nail	NOUN
dpc-2653	48	8	formation	formation	NOUN
dpc-2653	48	9	and	and	CCONJ
dpc-2653	48	10	growth	growth	NOUN
dpc-2653	48	11	,	,	PUNCT
dpc-2653	48	12	it	it	PRON
dpc-2653	48	13	is	be	AUX
dpc-2653	48	14	important	important	ADJ
dpc-2653	48	15	to	to	PART
dpc-2653	48	16	note	note	VERB
dpc-2653	48	17	that	that	SCONJ
dpc-2653	48	18	the	the	DET
dpc-2653	48	19	occurrence	occurrence	NOUN
dpc-2653	48	20	of	of	ADP
dpc-2653	48	21	these	these	DET
dpc-2653	48	22	nail	nail	NOUN
dpc-2653	48	23	toxic	toxic	ADJ
dpc-2653	48	24	effects	effect	NOUN
dpc-2653	48	25	is	be	AUX
dpc-2653	48	26	often	often	ADV
dpc-2653	48	27	delayed	delay	VERB
dpc-2653	48	28	relative	relative	ADJ
dpc-2653	48	29	to	to	ADP
dpc-2653	48	30	treatment	treatment	NOUN
dpc-2653	48	31	initiation	initiation	NOUN
dpc-2653	48	32	.	.	PUNCT
dpc-2653	49	1	clinical	clinical	ADJ
dpc-2653	49	2	presentation	presentation	NOUN
dpc-2653	49	3	varies	vary	VERB
dpc-2653	49	4	,	,	PUNCT
dpc-2653	49	5	depending	depend	VERB
dpc-2653	49	6	on	on	ADP
dpc-2653	49	7	the	the	DET
dpc-2653	49	8	nail	nail	NOUN
dpc-2653	49	9	structure	structure	NOUN
dpc-2653	49	10	affected	affect	VERB
dpc-2653	49	11	and	and	CCONJ
dpc-2653	49	12	the	the	DET
dpc-2653	49	13	severity	severity	NOUN
dpc-2653	49	14	of	of	ADP
dpc-2653	49	15	the	the	DET
dpc-2653	49	16	insult	insult	NOUN
dpc-2653	49	17	[	[	X
dpc-2653	49	18	4	4	NUM
dpc-2653	49	19	]	]	PUNCT
dpc-2653	49	20	.	.	PUNCT
dpc-2653	50	1	in	in	ADP
dpc-2653	50	2	terms	term	NOUN
dpc-2653	50	3	of	of	ADP
dpc-2653	50	4	topography	topography	NOUN
dpc-2653	50	5	,	,	PUNCT
dpc-2653	50	6	when	when	SCONJ
dpc-2653	50	7	the	the	DET
dpc-2653	50	8	nail	nail	NOUN
dpc-2653	50	9	bed	bed	NOUN
dpc-2653	50	10	is	be	AUX
dpc-2653	50	11	affected	affect	VERB
dpc-2653	50	12	,	,	PUNCT
dpc-2653	50	13	onycholysis	onycholysis	NOUN
dpc-2653	50	14	,	,	PUNCT
dpc-2653	50	15	apparent	apparent	ADJ
dpc-2653	50	16	leukonychia	leukonychia	NOUN
dpc-2653	50	17	and	and	CCONJ
dpc-2653	50	18	splinter	splinter	VERB
dpc-2653	50	19	haemorrhages	haemorrhage	NOUN
dpc-2653	50	20	may	may	AUX
dpc-2653	50	21	be	be	AUX
dpc-2653	50	22	observed	observe	VERB
dpc-2653	50	23	.	.	PUNCT
dpc-2653	51	1	toxicity	toxicity	NOUN
dpc-2653	51	2	targeting	target	VERB
dpc-2653	51	3	the	the	DET
dpc-2653	51	4	nail	nail	NOUN
dpc-2653	51	5	matrix	matrix	NOUN
dpc-2653	51	6	may	may	AUX
dpc-2653	51	7	result	result	VERB
dpc-2653	51	8	in	in	ADP
dpc-2653	51	9	the	the	DET
dpc-2653	51	10	appearance	appearance	NOUN
dpc-2653	51	11	of	of	ADP
dpc-2653	51	12	beau	beau	PROPN
dpc-2653	51	13	’s	’s	PART
dpc-2653	51	14	lines	line	NOUN
dpc-2653	51	15	,	,	PUNCT
dpc-2653	51	16	onychomadesis	onychomadesis	NOUN
dpc-2653	51	17	,	,	PUNCT
dpc-2653	51	18	true	true	ADJ
dpc-2653	51	19	leukonychia	leukonychia	NOUN
dpc-2653	51	20	,	,	PUNCT
dpc-2653	51	21	slower	slow	ADJ
dpc-2653	51	22	nail	nail	NOUN
dpc-2653	51	23	growth	growth	NOUN
dpc-2653	51	24	,	,	PUNCT
dpc-2653	51	25	nail	nail	NOUN
dpc-2653	51	26	thinning	thinning	NOUN
dpc-2653	51	27	,	,	PUNCT
dpc-2653	51	28	brittle	brittle	ADJ
dpc-2653	51	29	nails	nail	NOUN
dpc-2653	51	30	and	and	CCONJ
dpc-2653	51	31	melanonychia	melanonychia	PROPN
dpc-2653	51	32	.	.	PUNCT
dpc-2653	52	1	finally	finally	ADV
dpc-2653	52	2	,	,	PUNCT
dpc-2653	52	3	adverse	adverse	ADJ
dpc-2653	52	4	effects	effect	NOUN
dpc-2653	52	5	involving	involve	VERB
dpc-2653	52	6	the	the	DET
dpc-2653	52	7	perionychium	perionychium	NOUN
dpc-2653	52	8	may	may	AUX
dpc-2653	52	9	result	result	VERB
dpc-2653	52	10	in	in	ADP
dpc-2653	52	11	paronychia	paronychia	PROPN
dpc-2653	52	12	and	and	CCONJ
dpc-2653	52	13	pyogenic	pyogenic	ADJ
dpc-2653	52	14	granuloma	granuloma	NOUN
dpc-2653	52	15	[	[	X
dpc-2653	52	16	5	5	NUM
dpc-2653	52	17	,	,	PUNCT
dpc-2653	52	18	6	6	NUM
dpc-2653	52	19	]	]	PUNCT
dpc-2653	52	20	.	.	PUNCT
dpc-2653	53	1	a	a	DET
dpc-2653	53	2	combination	combination	NOUN
dpc-2653	53	3	of	of	ADP
dpc-2653	53	4	the	the	DET
dpc-2653	53	5	aforementioned	aforementioned	ADJ
dpc-2653	53	6	nail	nail	NOUN
dpc-2653	53	7	changes	change	NOUN
dpc-2653	53	8	is	be	AUX
dpc-2653	53	9	frequent	frequent	ADJ
dpc-2653	53	10	.	.	PUNCT
dpc-2653	54	1	the	the	DET
dpc-2653	54	2	most	most	ADV
dpc-2653	54	3	common	common	ADJ
dpc-2653	54	4	nail	nail	NOUN
dpc-2653	54	5	changes	change	NOUN
dpc-2653	54	6	reported	report	VERB
dpc-2653	54	7	in	in	ADP
dpc-2653	54	8	the	the	DET
dpc-2653	54	9	literature	literature	NOUN
dpc-2653	54	10	include	include	VERB
dpc-2653	54	11	leukonychia	leukonychia	PROPN
dpc-2653	54	12	,	,	PUNCT
dpc-2653	54	13	beau	beau	PROPN
dpc-2653	54	14	’s	’s	PART
dpc-2653	54	15	lines	line	NOUN
dpc-2653	54	16	,	,	PUNCT
dpc-2653	54	17	brittle	brittle	ADJ
dpc-2653	54	18	thin	thin	ADJ
dpc-2653	54	19	nails	nail	NOUN
dpc-2653	54	20	,	,	PUNCT
dpc-2653	54	21	and	and	CCONJ
dpc-2653	54	22	nail	nail	NOUN
dpc-2653	54	23	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	54	24	,	,	PUNCT
dpc-2653	54	25	which	which	PRON
dpc-2653	54	26	may	may	AUX
dpc-2653	54	27	be	be	AUX
dpc-2653	54	28	diffuse	diffuse	ADJ
dpc-2653	54	29	or	or	CCONJ
dpc-2653	54	30	horizontal	horizontal	ADJ
dpc-2653	54	31	[	[	X
dpc-2653	54	32	710	710	NUM
dpc-2653	54	33	]	]	PUNCT
dpc-2653	54	34	.	.	PUNCT
dpc-2653	55	1	taxanes	taxane	NOUN
dpc-2653	55	2	and	and	CCONJ
dpc-2653	55	3	anthracyclines	anthracycline	NOUN
dpc-2653	55	4	are	be	AUX
dpc-2653	55	5	the	the	DET
dpc-2653	55	6	antineoplastic	antineoplastic	ADJ
dpc-2653	55	7	regimens	regimen	NOUN
dpc-2653	55	8	mostly	mostly	ADV
dpc-2653	55	9	associated	associate	VERB
dpc-2653	55	10	with	with	ADP
dpc-2653	55	11	nail	nail	NOUN
dpc-2653	55	12	changes	change	NOUN
dpc-2653	55	13	.	.	PUNCT
dpc-2653	56	1	however	however	ADV
dpc-2653	56	2	,	,	PUNCT
dpc-2653	56	3	considering	consider	VERB
dpc-2653	56	4	that	that	SCONJ
dpc-2653	56	5	a	a	DET
dpc-2653	56	6	majority	majority	NOUN
dpc-2653	56	7	of	of	ADP
dpc-2653	56	8	the	the	DET
dpc-2653	56	9	reported	report	VERB
dpc-2653	56	10	patients	patient	NOUN
dpc-2653	56	11	were	be	AUX
dpc-2653	56	12	on	on	ADP
dpc-2653	56	13	multiple	multiple	ADJ
dpc-2653	56	14	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	56	15	agents	agent	NOUN
dpc-2653	56	16	,	,	PUNCT
dpc-2653	56	17	pinpointing	pinpoint	VERB
dpc-2653	56	18	the	the	DET
dpc-2653	56	19	offensive	offensive	ADJ
dpc-2653	56	20	drug	drug	NOUN
dpc-2653	56	21	was	be	AUX
dpc-2653	56	22	not	not	PART
dpc-2653	56	23	always	always	ADV
dpc-2653	56	24	feasible	feasible	ADJ
dpc-2653	56	25	.	.	PUNCT
dpc-2653	57	1	therefore	therefore	ADV
dpc-2653	57	2	,	,	PUNCT
dpc-2653	57	3	a	a	DET
dpc-2653	57	4	combination	combination	NOUN
dpc-2653	57	5	of	of	ADP
dpc-2653	57	6	agents	agent	NOUN
dpc-2653	57	7	was	be	AUX
dpc-2653	57	8	implicated	implicate	VERB
dpc-2653	57	9	in	in	ADP
dpc-2653	57	10	most	most	ADJ
dpc-2653	57	11	cases	case	NOUN
dpc-2653	57	12	.	.	PUNCT
dpc-2653	58	1	alkylating	alkylate	VERB
dpc-2653	58	2	agents	agent	NOUN
dpc-2653	58	3	classical	classical	ADJ
dpc-2653	58	4	alkylating	alkylating	NOUN
dpc-2653	58	5	:	:	PUNCT
dpc-2653	58	6	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	58	7	classical	classical	ADJ
dpc-2653	58	8	alkylating	alkylating	NOUN
dpc-2653	58	9	agents	agent	NOUN
dpc-2653	58	10	attach	attach	VERB
dpc-2653	58	11	an	an	DET
dpc-2653	58	12	alkyl	alkyl	ADJ
dpc-2653	58	13	group	group	NOUN
dpc-2653	58	14	to	to	ADP
dpc-2653	58	15	the	the	DET
dpc-2653	58	16	guanine	guanine	ADJ
dpc-2653	58	17	base	base	NOUN
dpc-2653	58	18	of	of	ADP
dpc-2653	58	19	dna	dna	PROPN
dpc-2653	58	20	and	and	CCONJ
dpc-2653	58	21	are	be	AUX
dpc-2653	58	22	used	use	VERB
dpc-2653	58	23	to	to	PART
dpc-2653	58	24	treat	treat	VERB
dpc-2653	58	25	leukaemia	leukaemia	NOUN
dpc-2653	58	26	,	,	PUNCT
dpc-2653	58	27	lymphoma	lymphoma	NOUN
dpc-2653	58	28	,	,	PUNCT
dpc-2653	58	29	hodgkin	hodgkin	NOUN
dpc-2653	58	30	disease	disease	NOUN
dpc-2653	58	31	,	,	PUNCT
dpc-2653	58	32	multiple	multiple	ADJ
dpc-2653	58	33	myeloma	myeloma	NOUN
dpc-2653	58	34	,	,	PUNCT
dpc-2653	58	35	sarcoma	sarcoma	NOUN
dpc-2653	58	36	,	,	PUNCT
dpc-2653	58	37	and	and	CCONJ
dpc-2653	58	38	review	review	VERB
dpc-2653	58	39	|	|	ADV
dpc-2653	58	40	dermatol	dermatol	ADJ
dpc-2653	58	41	pract	pract	NOUN
dpc-2653	58	42	concept	concept	NOUN
dpc-2653	58	43	.	.	PUNCT
dpc-2653	59	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	59	2	3	3	NUM
dpc-2653	59	3	figure	figure	NOUN
dpc-2653	59	4	1	1	NUM
dpc-2653	59	5	.	.	PUNCT
dpc-2653	60	1	nail	nail	NOUN
dpc-2653	60	2	toxicities	toxicity	NOUN
dpc-2653	60	3	due	due	ADJ
dpc-2653	60	4	to	to	ADP
dpc-2653	60	5	conventional	conventional	ADJ
dpc-2653	60	6	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	60	7	drugs	drug	NOUN
dpc-2653	60	8	.	.	PUNCT
dpc-2653	61	1	a.	a.	NOUN
dpc-2653	61	2	muehrcke	muehrcke	PROPN
dpc-2653	61	3	’s	’s	PART
dpc-2653	61	4	lines	line	NOUN
dpc-2653	61	5	due	due	ADP
dpc-2653	61	6	to	to	ADP
dpc-2653	61	7	treatment	treatment	NOUN
dpc-2653	61	8	with	with	ADP
dpc-2653	61	9	cisplatin	cisplatin	NOUN
dpc-2653	61	10	:	:	PUNCT
dpc-2653	61	11	transversal	transversal	ADJ
dpc-2653	61	12	white	white	ADJ
dpc-2653	61	13	lines	line	NOUN
dpc-2653	61	14	with	with	ADP
dpc-2653	61	15	healthy	healthy	ADJ
dpc-2653	61	16	nail	nail	NOUN
dpc-2653	61	17	bed	bed	NOUN
dpc-2653	61	18	between	between	ADP
dpc-2653	61	19	them	they	PRON
dpc-2653	61	20	.	.	PUNCT
dpc-2653	62	1	b.	b.	PROPN
dpc-2653	62	2	dermosopic	dermosopic	PROPN
dpc-2653	62	3	examination	examination	NOUN
dpc-2653	62	4	of	of	ADP
dpc-2653	62	5	the	the	DET
dpc-2653	62	6	same	same	ADJ
dpc-2653	62	7	patient	patient	NOUN
dpc-2653	62	8	with	with	ADP
dpc-2653	62	9	clear	clear	ADJ
dpc-2653	62	10	visualization	visualization	NOUN
dpc-2653	62	11	of	of	ADP
dpc-2653	62	12	the	the	DET
dpc-2653	62	13	leukonychia	leukonychia	NOUN
dpc-2653	62	14	in	in	ADP
dpc-2653	62	15	the	the	DET
dpc-2653	62	16	form	form	NOUN
dpc-2653	62	17	of	of	ADP
dpc-2653	62	18	muehrcke	muehrcke	NOUN
dpc-2653	62	19	’s	’s	PART
dpc-2653	62	20	lines	line	NOUN
dpc-2653	62	21	.	.	PUNCT
dpc-2653	63	1	c.	c.	PROPN
dpc-2653	63	2	red	red	VERB
dpc-2653	63	3	-	-	PUNCT
dpc-2653	63	4	brown	brown	ADJ
dpc-2653	63	5	discoloration	discoloration	NOUN
dpc-2653	63	6	of	of	ADP
dpc-2653	63	7	the	the	DET
dpc-2653	63	8	nails	nail	NOUN
dpc-2653	63	9	associated	associate	VERB
dpc-2653	63	10	with	with	ADP
dpc-2653	63	11	painful	painful	ADJ
dpc-2653	63	12	subungual	subungual	ADJ
dpc-2653	63	13	hematomas	hematoma	NOUN
dpc-2653	63	14	and	and	CCONJ
dpc-2653	63	15	onycholysis	onycholysis	NOUN
dpc-2653	63	16	following	follow	VERB
dpc-2653	63	17	treatment	treatment	NOUN
dpc-2653	63	18	with	with	ADP
dpc-2653	63	19	taxol	taxol	PROPN
dpc-2653	63	20	.	.	PUNCT
dpc-2653	64	1	d.	d.	PROPN
dpc-2653	64	2	dermoscopic	dermoscopic	PROPN
dpc-2653	64	3	image	image	NOUN
dpc-2653	64	4	of	of	ADP
dpc-2653	64	5	the	the	DET
dpc-2653	64	6	chemotherapy	chemotherapy	NOUN
dpc-2653	64	7	-	-	PUNCT
dpc-2653	64	8	induced	induce	VERB
dpc-2653	64	9	central	central	ADJ
dpc-2653	64	10	subungual	subungual	ADJ
dpc-2653	64	11	hematoma	hematoma	NOUN
dpc-2653	64	12	that	that	PRON
dpc-2653	64	13	differs	differ	VERB
dpc-2653	64	14	from	from	ADP
dpc-2653	64	15	traumatic	traumatic	ADJ
dpc-2653	64	16	subungal	subungal	ADJ
dpc-2653	64	17	hematoma	hematoma	NOUN
dpc-2653	64	18	:	:	PUNCT
dpc-2653	64	19	note	note	VERB
dpc-2653	64	20	the	the	DET
dpc-2653	64	21	bright	bright	ADJ
dpc-2653	64	22	red	red	ADJ
dpc-2653	64	23	color	color	NOUN
dpc-2653	64	24	with	with	ADP
dpc-2653	64	25	an	an	DET
dpc-2653	64	26	orange	orange	ADJ
dpc-2653	64	27	/	/	SYM
dpc-2653	64	28	brown	brown	ADJ
dpc-2653	64	29	halo	halo	NOUN
dpc-2653	64	30	(	(	PUNCT
dpc-2653	64	31	in	in	ADP
dpc-2653	64	32	trauma	trauma	NOUN
dpc-2653	64	33	:	:	PUNCT
dpc-2653	64	34	dark	dark	ADJ
dpc-2653	64	35	violet	violet	NOUN
dpc-2653	64	36	with	with	ADP
dpc-2653	64	37	globular	globular	ADJ
dpc-2653	64	38	pattern	pattern	NOUN
dpc-2653	64	39	accompanied	accompany	VERB
dpc-2653	64	40	by	by	ADP
dpc-2653	64	41	transversal	transversal	ADJ
dpc-2653	64	42	whitish	whitish	ADJ
dpc-2653	64	43	line	line	NOUN
dpc-2653	64	44	)	)	PUNCT
dpc-2653	64	45	.	.	PUNCT
dpc-2653	65	1	e.	e.	PROPN
dpc-2653	65	2	longitudinal	longitudinal	PROPN
dpc-2653	65	3	melanonychia	melanonychia	PROPN
dpc-2653	65	4	following	follow	VERB
dpc-2653	65	5	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	65	6	treatment	treatment	PROPN
dpc-2653	65	7	.	.	PUNCT
dpc-2653	66	1	f.	f.	PROPN
dpc-2653	66	2	dermoscopy	dermoscopy	VERB
dpc-2653	66	3	image	image	NOUN
dpc-2653	66	4	of	of	ADP
dpc-2653	66	5	the	the	DET
dpc-2653	66	6	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	66	7	-	-	PUNCT
dpc-2653	66	8	induced	induce	VERB
dpc-2653	66	9	melanonychia	melanonychia	NOUN
dpc-2653	66	10	with	with	ADP
dpc-2653	66	11	a	a	DET
dpc-2653	66	12	homogenous	homogenous	ADJ
dpc-2653	66	13	brown	brown	ADJ
dpc-2653	66	14	band	band	NOUN
dpc-2653	66	15	with	with	ADP
dpc-2653	66	16	absence	absence	NOUN
dpc-2653	66	17	of	of	ADP
dpc-2653	66	18	hutchinson	hutchinson	PROPN
dpc-2653	66	19	or	or	CCONJ
dpc-2653	66	20	micro	micro	NOUN
dpc-2653	66	21	-	-	PROPN
dpc-2653	66	22	hutcinson	hutcinson	NOUN
dpc-2653	66	23	’s	’s	PART
dpc-2653	66	24	sign	sign	NOUN
dpc-2653	66	25	.	.	PUNCT
dpc-2653	67	1	borders	border	NOUN
dpc-2653	67	2	appear	appear	VERB
dpc-2653	67	3	blurry	blurry	ADV
dpc-2653	67	4	but	but	CCONJ
dpc-2653	67	5	this	this	PRON
dpc-2653	67	6	may	may	AUX
dpc-2653	67	7	happen	happen	VERB
dpc-2653	67	8	in	in	ADP
dpc-2653	67	9	the	the	DET
dpc-2653	67	10	great	great	ADJ
dpc-2653	67	11	toenail	toenail	NOUN
dpc-2653	67	12	due	due	ADP
dpc-2653	67	13	to	to	ADP
dpc-2653	67	14	thickness	thickness	NOUN
dpc-2653	67	15	of	of	ADP
dpc-2653	67	16	the	the	DET
dpc-2653	67	17	nail	nail	NOUN
dpc-2653	67	18	plate	plate	NOUN
dpc-2653	67	19	.	.	PUNCT
dpc-2653	68	1	this	this	PRON
dpc-2653	68	2	is	be	AUX
dpc-2653	68	3	a	a	DET
dpc-2653	68	4	false	false	ADJ
dpc-2653	68	5	positive	positive	ADJ
dpc-2653	68	6	sign	sign	NOUN
dpc-2653	68	7	that	that	PRON
dpc-2653	68	8	should	should	AUX
dpc-2653	68	9	be	be	AUX
dpc-2653	68	10	interpreted	interpret	VERB
dpc-2653	68	11	together	together	ADV
dpc-2653	68	12	with	with	ADP
dpc-2653	68	13	the	the	DET
dpc-2653	68	14	clinical	clinical	ADJ
dpc-2653	68	15	history	history	NOUN
dpc-2653	68	16	of	of	ADP
dpc-2653	68	17	the	the	DET
dpc-2653	68	18	patient	patient	NOUN
dpc-2653	68	19	.	.	PUNCT
dpc-2653	69	1	table	table	NOUN
dpc-2653	69	2	1	1	NUM
dpc-2653	69	3	.	.	PUNCT
dpc-2653	69	4	proposed	propose	VERB
dpc-2653	69	5	management	management	NOUN
dpc-2653	69	6	algorithm	algorithm	NOUN
dpc-2653	69	7	for	for	ADP
dpc-2653	69	8	taxane	taxane	NOUN
dpc-2653	69	9	-	-	PUNCT
dpc-2653	69	10	related	relate	VERB
dpc-2653	69	11	onycholysis	onycholysis	NOUN
dpc-2653	69	12	[	[	X
dpc-2653	69	13	38	38	NUM
dpc-2653	69	14	]	]	PUNCT
dpc-2653	69	15	.	.	PUNCT
dpc-2653	70	1	grade	grade	NOUN
dpc-2653	70	2	0	0	NUM
dpc-2653	70	3	*	*	SYM
dpc-2653	70	4	•	•	NUM
dpc-2653	70	5	preventive	preventive	ADJ
dpc-2653	70	6	nail	nail	NOUN
dpc-2653	70	7	care	care	NOUN
dpc-2653	70	8	instructions	instruction	NOUN
dpc-2653	70	9	given	give	VERB
dpc-2653	70	10	•	•	ADP
dpc-2653	70	11	frozen	frozen	ADJ
dpc-2653	70	12	gloves	glove	NOUN
dpc-2653	70	13	should	should	AUX
dpc-2653	70	14	be	be	AUX
dpc-2653	70	15	considered	consider	VERB
dpc-2653	70	16	grade	grade	NOUN
dpc-2653	70	17	1	1	NUM
dpc-2653	70	18	*	*	NOUN
dpc-2653	70	19	asymptomatic	asymptomatic	ADJ
dpc-2653	70	20	separation	separation	NOUN
dpc-2653	70	21	of	of	ADP
dpc-2653	70	22	the	the	DET
dpc-2653	70	23	nail	nail	NOUN
dpc-2653	70	24	bed	bed	NOUN
dpc-2653	70	25	from	from	ADP
dpc-2653	70	26	the	the	DET
dpc-2653	70	27	nail	nail	NOUN
dpc-2653	70	28	plate	plate	NOUN
dpc-2653	70	29	or	or	CCONJ
dpc-2653	70	30	nail	nail	NOUN
dpc-2653	70	31	loss	loss	NOUN
dpc-2653	70	32	•	•	NUM
dpc-2653	70	33	continue	continue	VERB
dpc-2653	70	34	drug	drug	NOUN
dpc-2653	70	35	at	at	ADP
dpc-2653	70	36	current	current	ADJ
dpc-2653	70	37	dose	dose	NOUN
dpc-2653	70	38	and	and	CCONJ
dpc-2653	70	39	monitor	monitor	VERB
dpc-2653	70	40	for	for	ADP
dpc-2653	70	41	change	change	NOUN
dpc-2653	70	42	in	in	ADP
dpc-2653	70	43	severity	severity	NOUN
dpc-2653	70	44	•	•	ADP
dpc-2653	70	45	obtain	obtain	VERB
dpc-2653	70	46	bacterial	bacterial	ADJ
dpc-2653	70	47	/	/	SYM
dpc-2653	70	48	fungal	fungal	ADJ
dpc-2653	70	49	cultures	culture	NOUN
dpc-2653	70	50	if	if	SCONJ
dpc-2653	70	51	infection	infection	NOUN
dpc-2653	70	52	is	be	AUX
dpc-2653	70	53	suspected	suspect	VERB
dpc-2653	70	54	;	;	PUNCT
dpc-2653	70	55	apply	apply	VERB
dpc-2653	70	56	topical	topical	ADJ
dpc-2653	70	57	antibiotics	antibiotic	NOUN
dpc-2653	70	58	or	or	CCONJ
dpc-2653	70	59	fungal	fungal	ADJ
dpc-2653	70	60	agent	agent	NOUN
dpc-2653	70	61	•	•	NUM
dpc-2653	70	62	reassess	reassess	NOUN
dpc-2653	70	63	after	after	ADP
dpc-2653	70	64	2/3	2/3	NUM
dpc-2653	70	65	weeks	week	NOUN
dpc-2653	70	66	.	.	PUNCT
dpc-2653	71	1	if	if	SCONJ
dpc-2653	71	2	reaction	reaction	NOUN
dpc-2653	71	3	worsens	worsen	VERB
dpc-2653	71	4	proceed	proceed	VERB
dpc-2653	71	5	to	to	ADP
dpc-2653	71	6	next	next	ADJ
dpc-2653	71	7	step	step	NOUN
dpc-2653	71	8	grade	grade	NOUN
dpc-2653	71	9	2	2	NUM
dpc-2653	71	10	*	*	NOUN
dpc-2653	71	11	symptomatic	symptomatic	ADJ
dpc-2653	71	12	separation	separation	NOUN
dpc-2653	71	13	of	of	ADP
dpc-2653	71	14	the	the	DET
dpc-2653	71	15	nail	nail	NOUN
dpc-2653	71	16	bed	bed	NOUN
dpc-2653	71	17	from	from	ADP
dpc-2653	71	18	the	the	DET
dpc-2653	71	19	nail	nail	NOUN
dpc-2653	71	20	plate	plate	NOUN
dpc-2653	71	21	or	or	CCONJ
dpc-2653	71	22	nail	nail	NOUN
dpc-2653	71	23	loss	loss	NOUN
dpc-2653	71	24	;	;	PUNCT
dpc-2653	71	25	limiting	limit	VERB
dpc-2653	71	26	instrumental	instrumental	ADJ
dpc-2653	71	27	activities	activity	NOUN
dpc-2653	71	28	of	of	ADP
dpc-2653	71	29	daily	daily	ADJ
dpc-2653	71	30	living	live	VERB
dpc-2653	71	31	•	•	NUM
dpc-2653	71	32	continue	continue	VERB
dpc-2653	71	33	drug	drug	NOUN
dpc-2653	71	34	at	at	ADP
dpc-2653	71	35	current	current	ADJ
dpc-2653	71	36	dose	dose	NOUN
dpc-2653	71	37	and	and	CCONJ
dpc-2653	71	38	monitor	monitor	VERB
dpc-2653	71	39	for	for	ADP
dpc-2653	71	40	change	change	NOUN
dpc-2653	71	41	in	in	ADP
dpc-2653	71	42	severity	severity	NOUN
dpc-2653	71	43	•	•	ADP
dpc-2653	71	44	obtain	obtain	VERB
dpc-2653	71	45	bacterial	bacterial	ADJ
dpc-2653	71	46	/	/	SYM
dpc-2653	71	47	fungal	fungal	ADJ
dpc-2653	71	48	cultures	culture	NOUN
dpc-2653	71	49	if	if	SCONJ
dpc-2653	71	50	infection	infection	NOUN
dpc-2653	71	51	is	be	AUX
dpc-2653	71	52	suspected	suspect	VERB
dpc-2653	71	53	•	•	ADP
dpc-2653	71	54	if	if	SCONJ
dpc-2653	71	55	infection	infection	NOUN
dpc-2653	71	56	,	,	PUNCT
dpc-2653	71	57	begin	begin	VERB
dpc-2653	71	58	oral	oral	ADJ
dpc-2653	71	59	antibiotics	antibiotic	NOUN
dpc-2653	71	60	with	with	ADP
dpc-2653	71	61	anti	anti	ADJ
dpc-2653	71	62	–	–	ADJ
dpc-2653	71	63	staphylococcus	staphylococcus	ADJ
dpc-2653	71	64	aureus	aureus	NOUN
dpc-2653	71	65	and	and	CCONJ
dpc-2653	71	66	gram	gram	NOUN
dpc-2653	71	67	-	-	PUNCT
dpc-2653	71	68	positive	positive	ADJ
dpc-2653	71	69	coverage	coverage	NOUN
dpc-2653	71	70	•	•	ADP
dpc-2653	71	71	if	if	SCONJ
dpc-2653	71	72	painful	painful	ADJ
dpc-2653	71	73	hematoma	hematoma	NOUN
dpc-2653	71	74	or	or	CCONJ
dpc-2653	71	75	subungual	subungual	ADJ
dpc-2653	71	76	abscess	abscess	NOUN
dpc-2653	71	77	is	be	AUX
dpc-2653	71	78	suspected	suspect	VERB
dpc-2653	71	79	,	,	PUNCT
dpc-2653	71	80	partial	partial	ADJ
dpc-2653	71	81	or	or	CCONJ
dpc-2653	71	82	total	total	ADJ
dpc-2653	71	83	nail	nail	NOUN
dpc-2653	71	84	avulsion	avulsion	NOUN
dpc-2653	71	85	is	be	AUX
dpc-2653	71	86	required	require	VERB
dpc-2653	71	87	•	•	NUM
dpc-2653	71	88	pain	pain	NOUN
dpc-2653	71	89	control	control	NOUN
dpc-2653	71	90	•	•	NOUN
dpc-2653	71	91	reassess	reassess	NOUN
dpc-2653	71	92	after	after	ADP
dpc-2653	71	93	2	2	NUM
dpc-2653	71	94	weeks	week	NOUN
dpc-2653	71	95	;	;	PUNCT
dpc-2653	71	96	if	if	SCONJ
dpc-2653	71	97	reactions	reaction	NOUN
dpc-2653	71	98	worsen	worsen	VERB
dpc-2653	71	99	or	or	CCONJ
dpc-2653	71	100	do	do	AUX
dpc-2653	71	101	not	not	PART
dpc-2653	71	102	improve	improve	VERB
dpc-2653	71	103	interrupt	interrupt	ADJ
dpc-2653	71	104	treatment	treatment	NOUN
dpc-2653	71	105	until	until	SCONJ
dpc-2653	71	106	severity	severity	NOUN
dpc-2653	71	107	decreases	decrease	VERB
dpc-2653	71	108	to	to	ADP
dpc-2653	71	109	grade	grade	NOUN
dpc-2653	71	110	0	0	NUM
dpc-2653	71	111	-	-	SYM
dpc-2653	71	112	1	1	NUM
dpc-2653	71	113	grade	grade	NOUN
dpc-2653	71	114	3	3	NUM
dpc-2653	71	115	*	*	NOUN
dpc-2653	71	116	severe	severe	ADJ
dpc-2653	71	117	pain	pain	NOUN
dpc-2653	71	118	and/or	and/or	CCONJ
dpc-2653	71	119	superinfection	superinfection	NOUN
dpc-2653	71	120	;	;	PUNCT
dpc-2653	71	121	limiting	limit	VERB
dpc-2653	71	122	self	self	NOUN
dpc-2653	71	123	-	-	PUNCT
dpc-2653	71	124	care	care	NOUN
dpc-2653	71	125	activities	activity	NOUN
dpc-2653	71	126	of	of	ADP
dpc-2653	71	127	daily	daily	ADJ
dpc-2653	71	128	living	live	VERB
dpc-2653	71	129	interrupt	interrupt	ADJ
dpc-2653	71	130	treatment	treatment	NOUN
dpc-2653	71	131	until	until	SCONJ
dpc-2653	71	132	severity	severity	NOUN
dpc-2653	71	133	decreases	decrease	VERB
dpc-2653	71	134	to	to	ADP
dpc-2653	71	135	grade	grade	NOUN
dpc-2653	71	136	0	0	NUM
dpc-2653	71	137	-	-	SYM
dpc-2653	71	138	1	1	NUM
dpc-2653	71	139	,	,	PUNCT
dpc-2653	71	140	obtain	obtain	VERB
dpc-2653	71	141	bacterial	bacterial	ADJ
dpc-2653	71	142	/	/	SYM
dpc-2653	71	143	fungal	fungal	ADJ
dpc-2653	71	144	cultures	culture	NOUN
dpc-2653	71	145	if	if	SCONJ
dpc-2653	71	146	infection	infection	NOUN
dpc-2653	71	147	is	be	AUX
dpc-2653	71	148	suspected	suspect	VERB
dpc-2653	71	149	and	and	CCONJ
dpc-2653	71	150	continue	continue	VERB
dpc-2653	71	151	treatment	treatment	NOUN
dpc-2653	71	152	of	of	ADP
dpc-2653	71	153	nail	nail	NOUN
dpc-2653	71	154	reaction	reaction	NOUN
dpc-2653	71	155	with	with	ADP
dpc-2653	71	156	the	the	DET
dpc-2653	71	157	following	following	NOUN
dpc-2653	71	158	:	:	PUNCT
dpc-2653	71	159	•	•	X
dpc-2653	71	160	if	if	SCONJ
dpc-2653	71	161	infection	infection	NOUN
dpc-2653	71	162	,	,	PUNCT
dpc-2653	71	163	begin	begin	VERB
dpc-2653	71	164	oral	oral	ADJ
dpc-2653	71	165	antibiotics	antibiotic	NOUN
dpc-2653	71	166	with	with	ADP
dpc-2653	71	167	anti	anti	ADJ
dpc-2653	71	168	–	–	ADJ
dpc-2653	71	169	staphylococcus	staphylococcus	ADJ
dpc-2653	71	170	aureus	aureus	NOUN
dpc-2653	71	171	and	and	CCONJ
dpc-2653	71	172	gram	gram	NOUN
dpc-2653	71	173	-	-	PUNCT
dpc-2653	71	174	positive	positive	ADJ
dpc-2653	71	175	coverage	coverage	NOUN
dpc-2653	71	176	•	•	ADP
dpc-2653	71	177	if	if	SCONJ
dpc-2653	71	178	painful	painful	ADJ
dpc-2653	71	179	hematoma	hematoma	NOUN
dpc-2653	71	180	or	or	CCONJ
dpc-2653	71	181	subungual	subungual	ADJ
dpc-2653	71	182	abscess	abscess	NOUN
dpc-2653	71	183	is	be	AUX
dpc-2653	71	184	suspected	suspect	VERB
dpc-2653	71	185	,	,	PUNCT
dpc-2653	71	186	partial	partial	ADJ
dpc-2653	71	187	or	or	CCONJ
dpc-2653	71	188	total	total	ADJ
dpc-2653	71	189	nail	nail	NOUN
dpc-2653	71	190	avulsion	avulsion	NOUN
dpc-2653	71	191	is	be	AUX
dpc-2653	71	192	required	require	VERB
dpc-2653	71	193	•	•	NUM
dpc-2653	71	194	pain	pain	NOUN
dpc-2653	71	195	control	control	NOUN
dpc-2653	71	196	•	•	NOUN
dpc-2653	71	197	reassess	reassess	NOUN
dpc-2653	71	198	after	after	ADP
dpc-2653	71	199	2	2	NUM
dpc-2653	71	200	weeks	week	NOUN
dpc-2653	71	201	;	;	PUNCT
dpc-2653	71	202	if	if	SCONJ
dpc-2653	71	203	reactions	reaction	NOUN
dpc-2653	71	204	worsen	worsen	VERB
dpc-2653	71	205	or	or	CCONJ
dpc-2653	71	206	do	do	AUX
dpc-2653	71	207	not	not	PART
dpc-2653	71	208	improve	improve	VERB
dpc-2653	71	209	,	,	PUNCT
dpc-2653	71	210	consider	consider	VERB
dpc-2653	71	211	dose	dose	NOUN
dpc-2653	71	212	interruption	interruption	NOUN
dpc-2653	71	213	or	or	CCONJ
dpc-2653	71	214	discontinuation	discontinuation	NOUN
dpc-2653	71	215	per	per	ADP
dpc-2653	71	216	protocol	protocol	NOUN
dpc-2653	71	217	and	and	CCONJ
dpc-2653	71	218	switch	switch	VERB
dpc-2653	71	219	to	to	ADP
dpc-2653	71	220	another	another	DET
dpc-2653	71	221	antineoplastic	antineoplastic	ADJ
dpc-2653	71	222	agent	agent	NOUN
dpc-2653	71	223	*	*	VERB
dpc-2653	71	224	from	from	ADP
dpc-2653	71	225	nail	nail	NOUN
dpc-2653	71	226	loss	loss	NOUN
dpc-2653	71	227	clinical	clinical	ADJ
dpc-2653	71	228	grading	grading	NOUN
dpc-2653	71	229	,	,	PUNCT
dpc-2653	71	230	common	common	ADJ
dpc-2653	71	231	terminology	terminology	NOUN
dpc-2653	71	232	criteria	criterion	NOUN
dpc-2653	71	233	for	for	ADP
dpc-2653	71	234	adverse	adverse	ADJ
dpc-2653	71	235	events	event	NOUN
dpc-2653	71	236	(	(	PUNCT
dpc-2653	71	237	ctcae	ctcae	NOUN
dpc-2653	71	238	)	)	PUNCT
dpc-2653	71	239	,	,	PUNCT
dpc-2653	71	240	v4.02	v4.02	PROPN
dpc-2653	71	241	4	4	NUM
dpc-2653	71	242	review	review	NOUN
dpc-2653	71	243	|	|	ADV
dpc-2653	71	244	dermatol	dermatol	ADJ
dpc-2653	71	245	pract	pract	NOUN
dpc-2653	71	246	concept	concept	NOUN
dpc-2653	71	247	.	.	PUNCT
dpc-2653	72	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	72	2	table	table	NOUN
dpc-2653	72	3	2	2	NUM
dpc-2653	72	4	.	.	X
dpc-2653	72	5	conventional	conventional	ADJ
dpc-2653	72	6	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	72	7	drugs	drug	NOUN
dpc-2653	72	8	,	,	PUNCT
dpc-2653	72	9	mechanism	mechanism	NOUN
dpc-2653	72	10	of	of	ADP
dpc-2653	72	11	action	action	NOUN
dpc-2653	72	12	and	and	CCONJ
dpc-2653	72	13	associated	associate	VERB
dpc-2653	72	14	nail	nail	NOUN
dpc-2653	72	15	toxicity	toxicity	NOUN
dpc-2653	72	16	.	.	PUNCT
dpc-2653	73	1	drug	drug	NOUN
dpc-2653	73	2	class	class	NOUN
dpc-2653	73	3	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	73	4	drugs	drug	NOUN
dpc-2653	73	5	mechanism	mechanism	NOUN
dpc-2653	73	6	of	of	ADP
dpc-2653	73	7	action	action	NOUN
dpc-2653	73	8	nail	nail	NOUN
dpc-2653	73	9	disorders	disorder	NOUN
dpc-2653	73	10	alkylating	alkylate	VERB
dpc-2653	73	11	agents	agent	NOUN
dpc-2653	73	12	classical	classical	ADJ
dpc-2653	73	13	alkylating	alkylate	VERB
dpc-2653	73	14	platinum	platinum	NOUN
dpc-2653	73	15	agents	agent	NOUN
dpc-2653	73	16	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	73	17	cisplatin	cisplatin	PROPN
dpc-2653	73	18	carboplatin	carboplatin	PROPN
dpc-2653	73	19	oxaliplatin	oxaliplatin	PROPN
dpc-2653	73	20	crosslink	crosslink	NOUN
dpc-2653	73	21	with	with	ADP
dpc-2653	73	22	dna	dna	PROPN
dpc-2653	73	23	molecules	molecule	NOUN
dpc-2653	73	24	and	and	CCONJ
dpc-2653	73	25	damage	damage	NOUN
dpc-2653	73	26	cells	cell	NOUN
dpc-2653	73	27	in	in	ADP
dpc-2653	73	28	all	all	DET
dpc-2653	73	29	phases	phase	NOUN
dpc-2653	73	30	of	of	ADP
dpc-2653	73	31	the	the	DET
dpc-2653	73	32	cell	cell	NOUN
dpc-2653	73	33	cycle	cycle	NOUN
dpc-2653	73	34	diffuse	diffuse	NOUN
dpc-2653	73	35	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	73	36	longitudinal	longitudinal	ADJ
dpc-2653	73	37	melanonychia	melanonychia	PROPN
dpc-2653	73	38	beau	beau	PROPN
dpc-2653	73	39	’s	’s	PART
dpc-2653	73	40	lines	line	NOUN
dpc-2653	73	41	onychomadesis	onychomadesis	PROPN
dpc-2653	73	42	mees	mee	NOUN
dpc-2653	73	43	’	'	PUNCT
dpc-2653	73	44	lines	line	NOUN
dpc-2653	73	45	muehrcke	muehrcke	PROPN
dpc-2653	73	46	’s	’s	PART
dpc-2653	73	47	lines	line	NOUN
dpc-2653	73	48	onycholysis	onycholysis	PROPN
dpc-2653	73	49	beau	beau	PROPN
dpc-2653	73	50	’s	’s	PART
dpc-2653	73	51	lines	lines	PROPN
dpc-2653	73	52	hyperpigmentation	hyperpigmentation	PROPN
dpc-2653	73	53	muehrcke	muehrcke	PROPN
dpc-2653	73	54	’s	’s	PART
dpc-2653	73	55	lines	line	NOUN
dpc-2653	73	56	diffuse	diffuse	VERB
dpc-2653	73	57	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	73	58	muehrcke	muehrcke	NOUN
dpc-2653	73	59	’s	’s	PART
dpc-2653	73	60	lines	line	NOUN
dpc-2653	73	61	antimetabolites	antimetabolite	VERB
dpc-2653	73	62	analogs	analog	NOUN
dpc-2653	73	63	fluorouracil	fluorouracil	NOUN
dpc-2653	73	64	pemetrexed	pemetrexe	VERB
dpc-2653	73	65	5	5	NUM
dpc-2653	73	66	-	-	PUNCT
dpc-2653	73	67	fluorouracil	fluorouracil	NOUN
dpc-2653	73	68	capecitabine	capecitabine	NOUN
dpc-2653	73	69	tegafur	tegafur	PROPN
dpc-2653	73	70	substitute	substitute	NOUN
dpc-2653	73	71	building	building	NOUN
dpc-2653	73	72	blocks	block	NOUN
dpc-2653	73	73	of	of	ADP
dpc-2653	73	74	dna	dna	NOUN
dpc-2653	73	75	and	and	CCONJ
dpc-2653	73	76	rna	rna	NOUN
dpc-2653	73	77	and	and	CCONJ
dpc-2653	73	78	damage	damage	NOUN
dpc-2653	73	79	cells	cell	NOUN
dpc-2653	73	80	in	in	ADP
dpc-2653	73	81	the	the	DET
dpc-2653	73	82	s	s	NOUN
dpc-2653	73	83	phase	phase	NOUN
dpc-2653	73	84	melanonychia	melanonychia	NOUN
dpc-2653	73	85	onycholysis	onycholysis	NOUN
dpc-2653	73	86	beau	beau	PROPN
dpc-2653	73	87	’s	’s	PART
dpc-2653	73	88	lines	line	NOUN
dpc-2653	73	89	muehrcke	muehrcke	PROPN
dpc-2653	73	90	’s	’s	PART
dpc-2653	73	91	lines	line	NOUN
dpc-2653	73	92	paronychia	paronychia	VERB
dpc-2653	73	93	subungual	subungual	ADJ
dpc-2653	73	94	hyperkeratosis	hyperkeratosis	NOUN
dpc-2653	73	95	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	74	1	half	half	NOUN
dpc-2653	74	2	and	and	CCONJ
dpc-2653	74	3	half	half	NOUN
dpc-2653	74	4	nails	nail	NOUN
dpc-2653	74	5	onycholysis	onycholysis	NOUN
dpc-2653	74	6	onychomadesis	onychomadesis	NOUN
dpc-2653	74	7	onycholysis	onycholysis	NOUN
dpc-2653	74	8	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	74	9	longitudinal	longitudinal	ADJ
dpc-2653	74	10	melanonychia	melanonychia	NOUN
dpc-2653	74	11	antitumor	antitumor	PROPN
dpc-2653	74	12	antibiotics	antibiotic	NOUN
dpc-2653	74	13	anthracyclines	anthracycline	NOUN
dpc-2653	74	14	bleomycin	bleomycin	PROPN
dpc-2653	74	15	doxorubicin	doxorubicin	PROPN
dpc-2653	74	16	daunorubicin	daunorubicin	PROPN
dpc-2653	74	17	epirubicin	epirubicin	VERB
dpc-2653	74	18	intercalate	intercalate	NOUN
dpc-2653	74	19	with	with	ADP
dpc-2653	74	20	dna	dna	NOUN
dpc-2653	74	21	base	base	NOUN
dpc-2653	74	22	pairs	pair	NOUN
dpc-2653	74	23	and	and	CCONJ
dpc-2653	74	24	interfere	interfere	VERB
dpc-2653	74	25	with	with	ADP
dpc-2653	74	26	topoisomerase	topoisomerase	NOUN
dpc-2653	74	27	ii	ii	NOUN
dpc-2653	74	28	in	in	ADP
dpc-2653	74	29	all	all	DET
dpc-2653	74	30	cell	cell	NOUN
dpc-2653	74	31	cycle	cycle	NOUN
dpc-2653	74	32	phases	phase	NOUN
dpc-2653	74	33	induce	induce	VERB
dpc-2653	74	34	dna	dna	NOUN
dpc-2653	74	35	strand	strand	NOUN
dpc-2653	74	36	breaks	break	NOUN
dpc-2653	74	37	at	at	ADP
dpc-2653	74	38	g2	g2	PROPN
dpc-2653	74	39	phase	phase	NOUN
dpc-2653	74	40	diffuse	diffuse	ADJ
dpc-2653	74	41	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	74	42	beau	beau	PROPN
dpc-2653	74	43	’s	’s	PART
dpc-2653	74	44	lines	lines	PROPN
dpc-2653	74	45	mees	mee	NOUN
dpc-2653	74	46	’	'	PUNCT
dpc-2653	74	47	lines	line	NOUN
dpc-2653	74	48	muehrcke	muehrcke	PROPN
dpc-2653	74	49	’s	’s	PART
dpc-2653	74	50	lines	line	NOUN
dpc-2653	74	51	diffuse	diffuse	VERB
dpc-2653	74	52	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	74	53	mees	mees	PROPN
dpc-2653	74	54	’	'	PUNCT
dpc-2653	74	55	lines	line	NOUN
dpc-2653	74	56	beau	beau	PROPN
dpc-2653	74	57	’s	’s	PART
dpc-2653	74	58	lines	line	NOUN
dpc-2653	74	59	diffuse	diffuse	VERB
dpc-2653	74	60	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	74	61	longitudinal	longitudinal	ADJ
dpc-2653	74	62	melanonychia	melanonychia	NOUN
dpc-2653	74	63	beau	beau	PROPN
dpc-2653	74	64	’s	’s	PART
dpc-2653	74	65	lines	line	NOUN
dpc-2653	74	66	mitotic	mitotic	ADJ
dpc-2653	74	67	inhibitors	inhibitor	NOUN
dpc-2653	74	68	taxanes	taxane	VERB
dpc-2653	74	69	vinca	vinca	NOUN
dpc-2653	74	70	alkaloids	alkaloid	NOUN
dpc-2653	74	71	docetaxel	docetaxel	NOUN
dpc-2653	74	72	paclitaxel	paclitaxel	PROPN
dpc-2653	74	73	vincristine	vincristine	PROPN
dpc-2653	74	74	prevent	prevent	VERB
dpc-2653	74	75	the	the	DET
dpc-2653	74	76	formation	formation	NOUN
dpc-2653	74	77	of	of	ADP
dpc-2653	74	78	spindles	spindle	NOUN
dpc-2653	74	79	or	or	CCONJ
dpc-2653	74	80	microtubules	microtubule	NOUN
dpc-2653	74	81	during	during	ADP
dpc-2653	74	82	the	the	DET
dpc-2653	74	83	m	m	NOUN
dpc-2653	74	84	phase	phase	NOUN
dpc-2653	74	85	diffuse	diffuse	ADJ
dpc-2653	74	86	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	74	87	beau	beau	PROPN
dpc-2653	74	88	’s	’s	PART
dpc-2653	74	89	lines	line	NOUN
dpc-2653	74	90	onychomadesis	onychomadesis	PROPN
dpc-2653	74	91	mees	mee	NOUN
dpc-2653	74	92	’	'	PUNCT
dpc-2653	74	93	lines	line	NOUN
dpc-2653	74	94	paronychia	paronychia	VERB
dpc-2653	74	95	subungual	subungual	ADJ
dpc-2653	74	96	hyperkeratosis	hyperkeratosis	PROPN
dpc-2653	74	97	pyogenic	pyogenic	ADJ
dpc-2653	74	98	granuloma	granuloma	PROPN
dpc-2653	74	99	subungual	subungual	PROPN
dpc-2653	74	100	&	&	CCONJ
dpc-2653	74	101	splinter	splinter	VERB
dpc-2653	74	102	hemorrhage	hemorrhage	NOUN
dpc-2653	74	103	onycholysis	onycholysis	NOUN
dpc-2653	74	104	/	/	SYM
dpc-2653	74	105	exudative	exudative	ADJ
dpc-2653	74	106	onycholysis	onycholysis	NOUN
dpc-2653	74	107	brittle	brittle	ADJ
dpc-2653	74	108	nails	nail	NOUN
dpc-2653	74	109	onychorrhexis	onychorrhexi	VERB
dpc-2653	74	110	koilonychia	koilonychia	NOUN
dpc-2653	74	111	diffusehyperpigmentation	diffusehyperpigmentation	NOUN
dpc-2653	74	112	longitudinal	longitudinal	ADJ
dpc-2653	74	113	melanonychia	melanonychia	PROPN
dpc-2653	74	114	beau	beau	PROPN
dpc-2653	74	115	’s	’s	PART
dpc-2653	74	116	lines	line	NOUN
dpc-2653	74	117	onychomadesis	onychomadesis	PROPN
dpc-2653	74	118	mees	mee	NOUN
dpc-2653	74	119	’	'	PUNCT
dpc-2653	74	120	lines	line	NOUN
dpc-2653	74	121	muehrcke	muehrcke	PROPN
dpc-2653	74	122	’s	’s	PART
dpc-2653	74	123	lines	line	NOUN
dpc-2653	74	124	topoisomerase	topoisomerase	VERB
dpc-2653	74	125	inhibitors	inhibitor	NOUN
dpc-2653	74	126	topoisomerase	topoisomerase	PROPN
dpc-2653	74	127	ii	ii	PROPN
dpc-2653	74	128	etoposide	etoposide	NOUN
dpc-2653	74	129	interfere	interfere	VERB
dpc-2653	74	130	with	with	ADP
dpc-2653	74	131	topoisomerase	topoisomerase	NOUN
dpc-2653	74	132	i	i	PRON
dpc-2653	74	133	or	or	CCONJ
dpc-2653	74	134	ii	ii	PROPN
dpc-2653	74	135	during	during	ADP
dpc-2653	74	136	dna	dna	PROPN
dpc-2653	74	137	replication	replication	NOUN
dpc-2653	74	138	in	in	ADP
dpc-2653	74	139	all	all	DET
dpc-2653	74	140	cells	cell	NOUN
dpc-2653	74	141	in	in	ADP
dpc-2653	74	142	the	the	DET
dpc-2653	74	143	s	s	NOUN
dpc-2653	74	144	or	or	CCONJ
dpc-2653	74	145	g2	g2	PROPN
dpc-2653	74	146	phase	phase	NOUN
dpc-2653	74	147	paronychia	paronychia	PROPN
dpc-2653	74	148	review	review	NOUN
dpc-2653	74	149	|	|	ADV
dpc-2653	74	150	dermatol	dermatol	ADJ
dpc-2653	74	151	pract	pract	NOUN
dpc-2653	74	152	concept	concept	NOUN
dpc-2653	74	153	.	.	PUNCT
dpc-2653	75	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	75	2	5	5	NUM
dpc-2653	75	3	and	and	CCONJ
dpc-2653	75	4	are	be	AUX
dpc-2653	75	5	used	use	VERB
dpc-2653	75	6	to	to	PART
dpc-2653	75	7	treat	treat	VERB
dpc-2653	75	8	various	various	ADJ
dpc-2653	75	9	hematologic	hematologic	NOUN
dpc-2653	75	10	malignancies	malignancy	NOUN
dpc-2653	75	11	and	and	CCONJ
dpc-2653	75	12	solid	solid	ADJ
dpc-2653	75	13	tumors	tumor	NOUN
dpc-2653	75	14	.	.	PUNCT
dpc-2653	76	1	their	their	PRON
dpc-2653	76	2	main	main	ADJ
dpc-2653	76	3	adverse	adverse	ADJ
dpc-2653	76	4	effect	effect	NOUN
dpc-2653	76	5	is	be	AUX
dpc-2653	76	6	cardiotoxicity	cardiotoxicity	NOUN
dpc-2653	76	7	,	,	PUNCT
dpc-2653	76	8	which	which	PRON
dpc-2653	76	9	is	be	AUX
dpc-2653	76	10	limited	limit	VERB
dpc-2653	76	11	in	in	ADP
dpc-2653	76	12	the	the	DET
dpc-2653	76	13	liposomal	liposomal	NOUN
dpc-2653	76	14	pegylated	pegylate	VERB
dpc-2653	76	15	or	or	CCONJ
dpc-2653	76	16	encapsulated	encapsulate	VERB
dpc-2653	76	17	form	form	NOUN
dpc-2653	76	18	of	of	ADP
dpc-2653	76	19	anthracyclines	anthracycline	NOUN
dpc-2653	76	20	used	use	VERB
dpc-2653	76	21	for	for	ADP
dpc-2653	76	22	non	non	ADJ
dpc-2653	76	23	-	-	ADJ
dpc-2653	76	24	hodgkin	hodgkin	ADJ
dpc-2653	76	25	lymphoma	lymphoma	NOUN
dpc-2653	76	26	,	,	PUNCT
dpc-2653	76	27	multiple	multiple	ADJ
dpc-2653	76	28	myeloma	myeloma	NOUN
dpc-2653	76	29	,	,	PUNCT
dpc-2653	76	30	nsclc	nsclc	NOUN
dpc-2653	76	31	,	,	PUNCT
dpc-2653	76	32	aids	aid	NOUN
dpc-2653	76	33	-	-	PUNCT
dpc-2653	76	34	related	relate	VERB
dpc-2653	76	35	kaposi	kaposi	PROPN
dpc-2653	76	36	sarcoma	sarcoma	NOUN
dpc-2653	76	37	,	,	PUNCT
dpc-2653	76	38	and	and	CCONJ
dpc-2653	76	39	refractory	refractory	NOUN
dpc-2653	76	40	ovarian	ovarian	ADJ
dpc-2653	76	41	cancer	cancer	NOUN
dpc-2653	76	42	.	.	PUNCT
dpc-2653	77	1	both	both	DET
dpc-2653	77	2	drugs	drug	NOUN
dpc-2653	77	3	are	be	AUX
dpc-2653	77	4	administered	administer	VERB
dpc-2653	77	5	intravenously	intravenously	ADV
dpc-2653	77	6	[	[	X
dpc-2653	77	7	12	12	NUM
dpc-2653	77	8	]	]	PUNCT
dpc-2653	77	9	.	.	PUNCT
dpc-2653	78	1	doxorubicin	doxorubicin	PROPN
dpc-2653	78	2	may	may	AUX
dpc-2653	78	3	cause	cause	VERB
dpc-2653	78	4	diffuse	diffuse	ADJ
dpc-2653	78	5	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	78	6	,	,	PUNCT
dpc-2653	78	7	beau	beau	PROPN
dpc-2653	78	8	’s	’s	PART
dpc-2653	78	9	lines	line	NOUN
dpc-2653	78	10	,	,	PUNCT
dpc-2653	78	11	mees	mee	NOUN
dpc-2653	78	12	’	'	PUNCT
dpc-2653	78	13	lines	line	NOUN
dpc-2653	78	14	or	or	CCONJ
dpc-2653	78	15	muehrcke	muehrcke	NOUN
dpc-2653	78	16	’s	’s	PART
dpc-2653	78	17	lines	line	NOUN
dpc-2653	78	18	.	.	PUNCT
dpc-2653	79	1	daunorubicin	daunorubicin	PROPN
dpc-2653	79	2	may	may	AUX
dpc-2653	79	3	also	also	ADV
dpc-2653	79	4	cause	cause	VERB
dpc-2653	79	5	diffuse	diffuse	ADJ
dpc-2653	79	6	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	79	7	or	or	CCONJ
dpc-2653	79	8	mees	mee	NOUN
dpc-2653	79	9	’	'	PUNCT
dpc-2653	79	10	lines	line	NOUN
dpc-2653	79	11	(	(	PUNCT
dpc-2653	79	12	table	table	NOUN
dpc-2653	79	13	2	2	NUM
dpc-2653	79	14	)	)	PUNCT
dpc-2653	79	15	.	.	PUNCT
dpc-2653	80	1	bleomycin	bleomycin	PROPN
dpc-2653	80	2	bleomycin	bleomycin	PROPN
dpc-2653	80	3	is	be	AUX
dpc-2653	80	4	a	a	DET
dpc-2653	80	5	glycopeptide	glycopeptide	NOUN
dpc-2653	80	6	produced	produce	VERB
dpc-2653	80	7	by	by	ADP
dpc-2653	80	8	the	the	DET
dpc-2653	80	9	bacterium	bacterium	NOUN
dpc-2653	80	10	streptomyces	streptomyce	NOUN
dpc-2653	80	11	verticillus	verticillus	ADV
dpc-2653	80	12	and	and	CCONJ
dpc-2653	80	13	is	be	AUX
dpc-2653	80	14	used	use	VERB
dpc-2653	80	15	for	for	ADP
dpc-2653	80	16	the	the	DET
dpc-2653	80	17	treatment	treatment	NOUN
dpc-2653	80	18	of	of	ADP
dpc-2653	80	19	squamous	squamous	ADJ
dpc-2653	80	20	cell	cell	NOUN
dpc-2653	80	21	carcinoma	carcinoma	NOUN
dpc-2653	80	22	,	,	PUNCT
dpc-2653	80	23	lymphoma	lymphoma	NOUN
dpc-2653	80	24	,	,	PUNCT
dpc-2653	80	25	testicular	testicular	ADJ
dpc-2653	80	26	carcinoma	carcinoma	NOUN
dpc-2653	80	27	,	,	PUNCT
dpc-2653	80	28	and	and	CCONJ
dpc-2653	80	29	malignant	malignant	ADJ
dpc-2653	80	30	pleural	pleural	ADJ
dpc-2653	80	31	effusion	effusion	NOUN
dpc-2653	80	32	.	.	PUNCT
dpc-2653	81	1	it	it	PRON
dpc-2653	81	2	can	can	AUX
dpc-2653	81	3	be	be	AUX
dpc-2653	81	4	administered	administer	VERB
dpc-2653	81	5	intravenously	intravenously	ADV
dpc-2653	81	6	,	,	PUNCT
dpc-2653	81	7	intramuscularly	intramuscularly	ADV
dpc-2653	81	8	,	,	PUNCT
dpc-2653	81	9	intraperitoneally	intraperitoneally	ADV
dpc-2653	81	10	,	,	PUNCT
dpc-2653	81	11	intrapleurally	intrapleurally	ADV
dpc-2653	81	12	,	,	PUNCT
dpc-2653	81	13	or	or	CCONJ
dpc-2653	81	14	given	give	VERB
dpc-2653	81	15	as	as	ADP
dpc-2653	81	16	an	an	DET
dpc-2653	81	17	intralesional	intralesional	ADJ
dpc-2653	81	18	injection	injection	NOUN
dpc-2653	81	19	in	in	ADP
dpc-2653	81	20	recalcitrant	recalcitrant	ADJ
dpc-2653	81	21	warts	wart	NOUN
dpc-2653	81	22	,	,	PUNCT
dpc-2653	81	23	keloids	keloid	NOUN
dpc-2653	81	24	,	,	PUNCT
dpc-2653	81	25	and	and	CCONJ
dpc-2653	81	26	scars	scar	NOUN
dpc-2653	81	27	[	[	X
dpc-2653	81	28	17	17	NUM
dpc-2653	81	29	]	]	PUNCT
dpc-2653	81	30	.	.	PUNCT
dpc-2653	82	1	toxicity	toxicity	NOUN
dpc-2653	82	2	to	to	ADP
dpc-2653	82	3	bleomycin	bleomycin	PROPN
dpc-2653	82	4	occurs	occur	VERB
dpc-2653	82	5	in	in	ADP
dpc-2653	82	6	the	the	DET
dpc-2653	82	7	lungs	lung	NOUN
dpc-2653	82	8	and	and	CCONJ
dpc-2653	82	9	skin	skin	NOUN
dpc-2653	82	10	because	because	SCONJ
dpc-2653	82	11	these	these	DET
dpc-2653	82	12	organs	organ	NOUN
dpc-2653	82	13	lack	lack	VERB
dpc-2653	82	14	bleomycin	bleomycin	PROPN
dpc-2653	82	15	hydrolase	hydrolase	NOUN
dpc-2653	82	16	,	,	PUNCT
dpc-2653	82	17	an	an	DET
dpc-2653	82	18	inactivating	inactivate	VERB
dpc-2653	82	19	enzyme	enzyme	NOUN
dpc-2653	82	20	[	[	X
dpc-2653	82	21	18	18	NUM
dpc-2653	82	22	]	]	PUNCT
dpc-2653	82	23	.	.	PUNCT
dpc-2653	83	1	pulmonary	pulmonary	ADJ
dpc-2653	83	2	fibrosis	fibrosis	NOUN
dpc-2653	83	3	is	be	AUX
dpc-2653	83	4	a	a	DET
dpc-2653	83	5	serious	serious	ADJ
dpc-2653	83	6	complication	complication	NOUN
dpc-2653	83	7	of	of	ADP
dpc-2653	83	8	high	high	ADJ
dpc-2653	83	9	doses	dose	NOUN
dpc-2653	83	10	(	(	PUNCT
dpc-2653	83	11	>	>	SYM
dpc-2653	83	12	400	400	NUM
dpc-2653	83	13	units	unit	NOUN
dpc-2653	83	14	)	)	PUNCT
dpc-2653	83	15	,	,	PUNCT
dpc-2653	83	16	while	while	SCONJ
dpc-2653	83	17	cutaneous	cutaneous	ADJ
dpc-2653	83	18	reactions	reaction	NOUN
dpc-2653	83	19	usually	usually	ADV
dpc-2653	83	20	occur	occur	VERB
dpc-2653	83	21	between	between	ADP
dpc-2653	83	22	200	200	NUM
dpc-2653	83	23	to	to	PART
dpc-2653	83	24	300	300	NUM
dpc-2653	83	25	units	unit	NOUN
dpc-2653	83	26	[	[	X
dpc-2653	83	27	17	17	NUM
dpc-2653	83	28	]	]	PUNCT
dpc-2653	83	29	.	.	PUNCT
dpc-2653	84	1	bleomycin	bleomycin	PROPN
dpc-2653	84	2	may	may	AUX
dpc-2653	84	3	cause	cause	VERB
dpc-2653	84	4	nail	nail	NOUN
dpc-2653	84	5	dystrophy	dystrophy	NOUN
dpc-2653	84	6	,	,	PUNCT
dpc-2653	84	7	and	and	CCONJ
dpc-2653	84	8	horizontal	horizontal	ADJ
dpc-2653	84	9	or	or	CCONJ
dpc-2653	84	10	vertical	vertical	ADJ
dpc-2653	84	11	nail	nail	NOUN
dpc-2653	84	12	pigmentation	pigmentation	NOUN
dpc-2653	84	13	[	[	X
dpc-2653	84	14	17	17	NUM
dpc-2653	84	15	]	]	PUNCT
dpc-2653	84	16	(	(	PUNCT
dpc-2653	84	17	table	table	NOUN
dpc-2653	84	18	2	2	NUM
dpc-2653	84	19	)	)	PUNCT
dpc-2653	84	20	.	.	PUNCT
dpc-2653	85	1	mitotic	mitotic	ADJ
dpc-2653	85	2	/	/	SYM
dpc-2653	85	3	spindle	spindle	NOUN
dpc-2653	85	4	inhibitors	inhibitor	NOUN
dpc-2653	85	5	taxanes	taxane	NOUN
dpc-2653	85	6	:	:	PUNCT
dpc-2653	85	7	paclitaxel	paclitaxel	PROPN
dpc-2653	85	8	and	and	CCONJ
dpc-2653	85	9	docetaxel	docetaxel	PROPN
dpc-2653	85	10	taxanes	taxane	NOUN
dpc-2653	85	11	are	be	AUX
dpc-2653	85	12	among	among	ADP
dpc-2653	85	13	the	the	DET
dpc-2653	85	14	most	most	ADV
dpc-2653	85	15	commonly	commonly	ADV
dpc-2653	85	16	prescribed	prescribe	VERB
dpc-2653	85	17	anticancer	anticancer	NOUN
dpc-2653	85	18	drugs	drug	NOUN
dpc-2653	85	19	and	and	CCONJ
dpc-2653	85	20	were	be	AUX
dpc-2653	85	21	initially	initially	ADV
dpc-2653	85	22	derived	derive	VERB
dpc-2653	85	23	from	from	ADP
dpc-2653	85	24	yew	yew	PROPN
dpc-2653	85	25	trees	tree	NOUN
dpc-2653	85	26	.	.	PUNCT
dpc-2653	86	1	paclitaxel	paclitaxel	PROPN
dpc-2653	86	2	is	be	AUX
dpc-2653	86	3	a	a	DET
dpc-2653	86	4	natural	natural	ADJ
dpc-2653	86	5	extract	extract	NOUN
dpc-2653	86	6	derived	derive	VERB
dpc-2653	86	7	from	from	ADP
dpc-2653	86	8	the	the	DET
dpc-2653	86	9	bark	bark	NOUN
dpc-2653	86	10	of	of	ADP
dpc-2653	86	11	the	the	DET
dpc-2653	86	12	pacific	pacific	PROPN
dpc-2653	86	13	yew	yew	PROPN
dpc-2653	86	14	tree	tree	NOUN
dpc-2653	86	15	(	(	PUNCT
dpc-2653	86	16	taxus	taxus	NOUN
dpc-2653	86	17	brevifolia	brevifolia	NOUN
dpc-2653	86	18	)	)	PUNCT
dpc-2653	86	19	that	that	PRON
dpc-2653	86	20	became	become	VERB
dpc-2653	86	21	commercially	commercially	ADV
dpc-2653	86	22	available	available	ADJ
dpc-2653	86	23	in	in	ADP
dpc-2653	86	24	1992	1992	NUM
dpc-2653	86	25	.	.	PUNCT
dpc-2653	87	1	on	on	ADP
dpc-2653	87	2	the	the	DET
dpc-2653	87	3	other	other	ADJ
dpc-2653	87	4	hand	hand	NOUN
dpc-2653	87	5	,	,	PUNCT
dpc-2653	87	6	docetaxel	docetaxel	PROPN
dpc-2653	87	7	is	be	AUX
dpc-2653	87	8	a	a	DET
dpc-2653	87	9	semisynthetic	semisynthetic	ADJ
dpc-2653	87	10	analogue	analogue	NOUN
dpc-2653	87	11	of	of	ADP
dpc-2653	87	12	paclitaxel	paclitaxel	PROPN
dpc-2653	87	13	synthesized	synthesize	VERB
dpc-2653	87	14	from	from	ADP
dpc-2653	87	15	the	the	DET
dpc-2653	87	16	needles	needle	NOUN
dpc-2653	87	17	of	of	ADP
dpc-2653	87	18	the	the	DET
dpc-2653	87	19	european	european	ADJ
dpc-2653	87	20	yew	yew	PROPN
dpc-2653	87	21	tree	tree	NOUN
dpc-2653	87	22	(	(	PUNCT
dpc-2653	87	23	taxus	taxus	NOUN
dpc-2653	87	24	baccata	baccata	NOUN
dpc-2653	87	25	)	)	PUNCT
dpc-2653	87	26	.	.	PUNCT
dpc-2653	88	1	both	both	DET
dpc-2653	88	2	drugs	drug	NOUN
dpc-2653	88	3	act	act	VERB
dpc-2653	88	4	as	as	ADP
dpc-2653	88	5	antimicrotubule	antimicrotubule	NOUN
dpc-2653	88	6	agents	agent	NOUN
dpc-2653	88	7	by	by	ADP
dpc-2653	88	8	promoting	promote	VERB
dpc-2653	88	9	the	the	DET
dpc-2653	88	10	polymerisation	polymerisation	NOUN
dpc-2653	88	11	of	of	ADP
dpc-2653	88	12	tubulin	tubulin	NOUN
dpc-2653	88	13	into	into	ADP
dpc-2653	88	14	highly	highly	ADV
dpc-2653	88	15	stable	stable	ADJ
dpc-2653	88	16	intracellular	intracellular	ADJ
dpc-2653	88	17	microtubules	microtubule	NOUN
dpc-2653	88	18	,	,	PUNCT
dpc-2653	88	19	thus	thus	ADV
dpc-2653	88	20	disrupting	disrupt	VERB
dpc-2653	88	21	mitosis	mitosis	NOUN
dpc-2653	88	22	and	and	CCONJ
dpc-2653	88	23	normal	normal	ADJ
dpc-2653	88	24	cell	cell	NOUN
dpc-2653	88	25	division	division	NOUN
dpc-2653	88	26	,	,	PUNCT
dpc-2653	88	27	and	and	CCONJ
dpc-2653	88	28	eventually	eventually	ADV
dpc-2653	88	29	leading	lead	VERB
dpc-2653	88	30	to	to	ADP
dpc-2653	88	31	cell	cell	NOUN
dpc-2653	88	32	death	death	NOUN
dpc-2653	89	1	[	[	X
dpc-2653	89	2	1921	1921	NUM
dpc-2653	89	3	]	]	PUNCT
dpc-2653	89	4	.	.	PUNCT
dpc-2653	90	1	because	because	SCONJ
dpc-2653	90	2	of	of	ADP
dpc-2653	90	3	their	their	PRON
dpc-2653	90	4	highly	highly	ADV
dpc-2653	90	5	hydrophobic	hydrophobic	ADJ
dpc-2653	90	6	properties	property	NOUN
dpc-2653	90	7	,	,	PUNCT
dpc-2653	90	8	they	they	PRON
dpc-2653	90	9	require	require	VERB
dpc-2653	90	10	the	the	DET
dpc-2653	90	11	use	use	NOUN
dpc-2653	90	12	of	of	ADP
dpc-2653	90	13	solvents	solvent	NOUN
dpc-2653	90	14	(	(	PUNCT
dpc-2653	90	15	non	non	ADJ
dpc-2653	90	16	-	-	ADJ
dpc-2653	90	17	ionic	ionic	ADJ
dpc-2653	90	18	polyoxyethylated	polyoxyethylated	ADJ
dpc-2653	90	19	castor	castor	NOUN
dpc-2653	90	20	oil	oil	NOUN
dpc-2653	90	21	-cremophor	-cremophor	PROPN
dpc-2653	90	22	el	el	PROPN
dpc-2653	90	23	®	®	PROPN
dpc-2653	90	24	for	for	ADP
dpc-2653	90	25	paclitaxel	paclitaxel	NOUN
dpc-2653	90	26	;	;	PUNCT
dpc-2653	90	27	non	non	ADJ
dpc-2653	90	28	-	-	ADJ
dpc-2653	90	29	ionic	ionic	ADJ
dpc-2653	90	30	surfactant	surfactant	NOUN
dpc-2653	90	31	polysorbate	polysorbate	NOUN
dpc-2653	90	32	80	80	NUM
dpc-2653	90	33	for	for	ADP
dpc-2653	90	34	docetaxel	docetaxel	NOUN
dpc-2653	90	35	)	)	PUNCT
dpc-2653	90	36	to	to	PART
dpc-2653	90	37	facilitate	facilitate	VERB
dpc-2653	90	38	parenteral	parenteral	ADJ
dpc-2653	90	39	administration	administration	NOUN
dpc-2653	90	40	.	.	PUNCT
dpc-2653	91	1	the	the	DET
dpc-2653	91	2	drugs	drug	NOUN
dpc-2653	91	3	are	be	AUX
dpc-2653	91	4	approved	approve	VERB
dpc-2653	91	5	for	for	ADP
dpc-2653	91	6	a	a	DET
dpc-2653	91	7	number	number	NOUN
dpc-2653	91	8	of	of	ADP
dpc-2653	91	9	indications	indication	NOUN
dpc-2653	91	10	in	in	ADP
dpc-2653	91	11	the	the	DET
dpc-2653	91	12	us	us	PROPN
dpc-2653	91	13	and	and	CCONJ
dpc-2653	91	14	europe	europe	PROPN
dpc-2653	91	15	.	.	PUNCT
dpc-2653	92	1	paclitaxel	paclitaxel	PROPN
dpc-2653	92	2	was	be	AUX
dpc-2653	92	3	the	the	DET
dpc-2653	92	4	first	first	ADJ
dpc-2653	92	5	taxane	taxane	NOUN
dpc-2653	92	6	discovered	discover	VERB
dpc-2653	92	7	,	,	PUNCT
dpc-2653	92	8	is	be	AUX
dpc-2653	92	9	generally	generally	ADV
dpc-2653	92	10	administered	administer	VERB
dpc-2653	92	11	by	by	ADP
dpc-2653	92	12	weekly	weekly	ADJ
dpc-2653	92	13	infusion	infusion	NOUN
dpc-2653	92	14	(	(	PUNCT
dpc-2653	92	15	80	80	NUM
dpc-2653	92	16	mg	mg	PROPN
dpc-2653	92	17	/	/	SYM
dpc-2653	92	18	m2	m2	PROPN
dpc-2653	92	19	)	)	PUNCT
dpc-2653	92	20	and	and	CCONJ
dpc-2653	92	21	is	be	AUX
dpc-2653	92	22	currently	currently	ADV
dpc-2653	92	23	approved	approve	VERB
dpc-2653	92	24	by	by	ADP
dpc-2653	92	25	the	the	DET
dpc-2653	92	26	us	us	PROPN
dpc-2653	92	27	food	food	NOUN
dpc-2653	92	28	and	and	CCONJ
dpc-2653	92	29	drug	drug	NOUN
dpc-2653	92	30	administration	administration	NOUN
dpc-2653	92	31	for	for	ADP
dpc-2653	92	32	the	the	DET
dpc-2653	92	33	treatment	treatment	NOUN
dpc-2653	92	34	of	of	ADP
dpc-2653	92	35	breast	breast	NOUN
dpc-2653	92	36	cancer	cancer	NOUN
dpc-2653	92	37	,	,	PUNCT
dpc-2653	92	38	nsclc	nsclc	NOUN
dpc-2653	92	39	,	,	PUNCT
dpc-2653	92	40	aids	aid	NOUN
dpc-2653	92	41	-	-	PUNCT
dpc-2653	92	42	related	relate	VERB
dpc-2653	92	43	kaposi	kaposi	PROPN
dpc-2653	92	44	sarcoma	sarcoma	NOUN
dpc-2653	92	45	,	,	PUNCT
dpc-2653	92	46	and	and	CCONJ
dpc-2653	92	47	ovarian	ovarian	ADJ
dpc-2653	92	48	cancer	cancer	NOUN
dpc-2653	92	49	.	.	PUNCT
dpc-2653	93	1	docetaxel	docetaxel	PROPN
dpc-2653	93	2	,	,	PUNCT
dpc-2653	93	3	developed	develop	VERB
dpc-2653	93	4	later	later	ADV
dpc-2653	93	5	,	,	PUNCT
dpc-2653	93	6	is	be	AUX
dpc-2653	93	7	infused	infuse	VERB
dpc-2653	93	8	(	(	PUNCT
dpc-2653	93	9	100	100	NUM
dpc-2653	93	10	mg	mg	PROPN
dpc-2653	93	11	/	/	SYM
dpc-2653	93	12	m2	m2	PROPN
dpc-2653	93	13	)	)	PUNCT
dpc-2653	93	14	every	every	DET
dpc-2653	93	15	three	three	NUM
dpc-2653	93	16	weeks	week	NOUN
dpc-2653	93	17	and	and	CCONJ
dpc-2653	93	18	is	be	AUX
dpc-2653	93	19	used	use	VERB
dpc-2653	93	20	for	for	ADP
dpc-2653	93	21	the	the	DET
dpc-2653	93	22	management	management	NOUN
dpc-2653	93	23	of	of	ADP
dpc-2653	93	24	advanced	advanced	ADJ
dpc-2653	93	25	breast	breast	NOUN
dpc-2653	93	26	,	,	PUNCT
dpc-2653	93	27	gastric	gastric	ADJ
dpc-2653	93	28	,	,	PUNCT
dpc-2653	93	29	nsclcs	nsclcs	NOUN
dpc-2653	93	30	,	,	PUNCT
dpc-2653	93	31	hormone	hormone	NOUN
dpc-2653	93	32	-	-	PUNCT
dpc-2653	93	33	refractory	refractory	NOUN
dpc-2653	93	34	prostate	prostate	NOUN
dpc-2653	93	35	cancers	cancer	NOUN
dpc-2653	93	36	of	of	ADP
dpc-2653	93	37	the	the	DET
dpc-2653	93	38	lung	lung	NOUN
dpc-2653	93	39	,	,	PUNCT
dpc-2653	93	40	breast	breast	NOUN
dpc-2653	93	41	and	and	CCONJ
dpc-2653	93	42	ovary	ovary	ADJ
dpc-2653	94	1	[	[	X
dpc-2653	94	2	11	11	NUM
dpc-2653	94	3	]	]	PUNCT
dpc-2653	94	4	.	.	PUNCT
dpc-2653	95	1	all	all	PRON
dpc-2653	95	2	can	can	AUX
dpc-2653	95	3	be	be	AUX
dpc-2653	95	4	administered	administer	VERB
dpc-2653	95	5	intravenously	intravenously	ADV
dpc-2653	95	6	,	,	PUNCT
dpc-2653	95	7	though	though	SCONJ
dpc-2653	95	8	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	95	9	can	can	AUX
dpc-2653	95	10	be	be	AUX
dpc-2653	95	11	also	also	ADV
dpc-2653	95	12	taken	take	VERB
dpc-2653	95	13	orally	orally	ADV
dpc-2653	96	1	[	[	X
dpc-2653	96	2	12	12	NUM
dpc-2653	96	3	]	]	PUNCT
dpc-2653	96	4	.	.	PUNCT
dpc-2653	97	1	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	97	2	may	may	AUX
dpc-2653	97	3	cause	cause	VERB
dpc-2653	97	4	diffuse	diffuse	ADJ
dpc-2653	97	5	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	97	6	,	,	PUNCT
dpc-2653	97	7	longitudinal	longitudinal	ADJ
dpc-2653	97	8	melanonychia	melanonychia	NOUN
dpc-2653	97	9	,	,	PUNCT
dpc-2653	97	10	beau	beau	PROPN
dpc-2653	97	11	’s	’s	PART
dpc-2653	97	12	lines	line	NOUN
dpc-2653	97	13	,	,	PUNCT
dpc-2653	97	14	onychomadesis	onychomadesis	PROPN
dpc-2653	97	15	,	,	PUNCT
dpc-2653	97	16	mees	mee	NOUN
dpc-2653	97	17	’	'	PUNCT
dpc-2653	97	18	lines	line	NOUN
dpc-2653	97	19	,	,	PUNCT
dpc-2653	97	20	muehrcke	muehrcke	NOUN
dpc-2653	97	21	’s	’s	PART
dpc-2653	97	22	lines	line	NOUN
dpc-2653	97	23	and	and	CCONJ
dpc-2653	97	24	onycholysis	onycholysis	NOUN
dpc-2653	97	25	(	(	PUNCT
dpc-2653	97	26	table	table	NOUN
dpc-2653	97	27	2	2	NUM
dpc-2653	97	28	)	)	PUNCT
dpc-2653	97	29	.	.	PUNCT
dpc-2653	98	1	platinum	platinum	NOUN
dpc-2653	98	2	agents	agent	NOUN
dpc-2653	98	3	:	:	PUNCT
dpc-2653	98	4	cisplatin	cisplatin	NOUN
dpc-2653	98	5	,	,	PUNCT
dpc-2653	98	6	carboplatin	carboplatin	NOUN
dpc-2653	98	7	,	,	PUNCT
dpc-2653	98	8	and	and	CCONJ
dpc-2653	98	9	 	 	SPACE
dpc-2653	98	10	oxaliplatin	oxaliplatin	NOUN
dpc-2653	98	11	platinum	platinum	NOUN
dpc-2653	98	12	agents	agent	NOUN
dpc-2653	98	13	form	form	VERB
dpc-2653	98	14	reactive	reactive	ADJ
dpc-2653	98	15	platinum	platinum	NOUN
dpc-2653	98	16	complexes	complex	NOUN
dpc-2653	98	17	that	that	PRON
dpc-2653	98	18	crosslink	crosslink	VERB
dpc-2653	98	19	with	with	ADP
dpc-2653	98	20	dna	dna	PROPN
dpc-2653	98	21	molecules	molecule	NOUN
dpc-2653	98	22	,	,	PUNCT
dpc-2653	98	23	inhibiting	inhibit	VERB
dpc-2653	98	24	dna	dna	ADJ
dpc-2653	98	25	synthesis	synthesis	NOUN
dpc-2653	98	26	and	and	CCONJ
dpc-2653	98	27	repair	repair	NOUN
dpc-2653	98	28	,	,	PUNCT
dpc-2653	98	29	and	and	CCONJ
dpc-2653	98	30	are	be	AUX
dpc-2653	98	31	given	give	VERB
dpc-2653	98	32	intravenously	intravenously	ADV
dpc-2653	98	33	.	.	PUNCT
dpc-2653	99	1	cisplatin	cisplatin	NOUN
dpc-2653	99	2	is	be	AUX
dpc-2653	99	3	an	an	DET
dpc-2653	99	4	older	old	ADJ
dpc-2653	99	5	drug	drug	NOUN
dpc-2653	99	6	that	that	PRON
dpc-2653	99	7	causes	cause	VERB
dpc-2653	99	8	many	many	ADJ
dpc-2653	99	9	side	side	NOUN
dpc-2653	99	10	effects	effect	NOUN
dpc-2653	99	11	(	(	PUNCT
dpc-2653	99	12	eg	eg	NOUN
dpc-2653	99	13	,	,	PUNCT
dpc-2653	99	14	ototoxicity	ototoxicity	NOUN
dpc-2653	99	15	,	,	PUNCT
dpc-2653	99	16	neurotoxicity	neurotoxicity	NOUN
dpc-2653	99	17	,	,	PUNCT
dpc-2653	99	18	nephrotoxicity	nephrotoxicity	NOUN
dpc-2653	99	19	,	,	PUNCT
dpc-2653	99	20	and	and	CCONJ
dpc-2653	99	21	emetogenicity	emetogenicity	NOUN
dpc-2653	99	22	)	)	PUNCT
dpc-2653	99	23	and	and	CCONJ
dpc-2653	99	24	is	be	AUX
dpc-2653	99	25	used	use	VERB
dpc-2653	99	26	to	to	PART
dpc-2653	99	27	treat	treat	VERB
dpc-2653	99	28	a	a	DET
dpc-2653	99	29	wide	wide	ADJ
dpc-2653	99	30	variety	variety	NOUN
dpc-2653	99	31	of	of	ADP
dpc-2653	99	32	solid	solid	ADJ
dpc-2653	99	33	tumors	tumor	NOUN
dpc-2653	99	34	.	.	PUNCT
dpc-2653	100	1	cisplatin	cisplatin	NOUN
dpc-2653	100	2	may	may	AUX
dpc-2653	100	3	cause	cause	VERB
dpc-2653	100	4	beau	beau	PROPN
dpc-2653	100	5	’s	’s	PART
dpc-2653	100	6	lines	line	NOUN
dpc-2653	100	7	,	,	PUNCT
dpc-2653	100	8	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	100	9	or	or	CCONJ
dpc-2653	100	10	muehrcke	muehrcke	NOUN
dpc-2653	100	11	’s	’s	PART
dpc-2653	100	12	lines	line	NOUN
dpc-2653	100	13	.	.	PUNCT
dpc-2653	101	1	carboplatin	carboplatin	NOUN
dpc-2653	101	2	and	and	CCONJ
dpc-2653	101	3	oxaliplatin	oxaliplatin	NOUN
dpc-2653	101	4	are	be	AUX
dpc-2653	101	5	newer	new	ADJ
dpc-2653	101	6	-	-	PUNCT
dpc-2653	101	7	generation	generation	NOUN
dpc-2653	101	8	platinum	platinum	NOUN
dpc-2653	101	9	agents	agent	NOUN
dpc-2653	101	10	with	with	ADP
dpc-2653	101	11	less	less	ADJ
dpc-2653	101	12	toxicity	toxicity	NOUN
dpc-2653	101	13	[	[	X
dpc-2653	101	14	13	13	NUM
dpc-2653	101	15	]	]	PUNCT
dpc-2653	101	16	.	.	PUNCT
dpc-2653	102	1	these	these	DET
dpc-2653	102	2	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	102	3	agents	agent	NOUN
dpc-2653	102	4	may	may	AUX
dpc-2653	102	5	cause	cause	VERB
dpc-2653	102	6	diffuse	diffuse	ADJ
dpc-2653	102	7	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	102	8	or	or	CCONJ
dpc-2653	102	9	muehrcke	muehrcke	NOUN
dpc-2653	102	10	’s	’s	PART
dpc-2653	102	11	lines	line	NOUN
dpc-2653	102	12	(	(	PUNCT
dpc-2653	102	13	table	table	NOUN
dpc-2653	102	14	2	2	NUM
dpc-2653	102	15	)	)	PUNCT
dpc-2653	102	16	.	.	PUNCT
dpc-2653	103	1	antimetabolites	antimetabolite	NOUN
dpc-2653	103	2	analogs	analog	NOUN
dpc-2653	103	3	:	:	PUNCT
dpc-2653	103	4	pemetrexed	pemetrexed	PROPN
dpc-2653	103	5	pemetrexed	pemetrexed	PROPN
dpc-2653	103	6	is	be	AUX
dpc-2653	103	7	an	an	DET
dpc-2653	103	8	intravenously	intravenously	ADV
dpc-2653	103	9	administered	administer	VERB
dpc-2653	103	10	folate	folate	NOUN
dpc-2653	103	11	analogue	analogue	NOUN
dpc-2653	103	12	that	that	PRON
dpc-2653	103	13	interferes	interfere	VERB
dpc-2653	103	14	with	with	ADP
dpc-2653	103	15	enzymes	enzyme	NOUN
dpc-2653	103	16	required	require	VERB
dpc-2653	103	17	for	for	ADP
dpc-2653	103	18	pyrimidine	pyrimidine	NOUN
dpc-2653	103	19	and	and	CCONJ
dpc-2653	103	20	purine	purine	NOUN
dpc-2653	103	21	synthesis	synthesis	NOUN
dpc-2653	103	22	,	,	PUNCT
dpc-2653	103	23	and	and	CCONJ
dpc-2653	103	24	is	be	AUX
dpc-2653	103	25	used	use	VERB
dpc-2653	103	26	for	for	ADP
dpc-2653	103	27	the	the	DET
dpc-2653	103	28	treatment	treatment	NOUN
dpc-2653	103	29	of	of	ADP
dpc-2653	103	30	mesothelioma	mesothelioma	NOUN
dpc-2653	103	31	,	,	PUNCT
dpc-2653	103	32	non	non	ADJ
dpc-2653	103	33	-	-	ADJ
dpc-2653	103	34	small	small	ADJ
dpc-2653	103	35	cell	cell	NOUN
dpc-2653	103	36	lung	lung	NOUN
dpc-2653	103	37	carcinoma	carcinoma	NOUN
dpc-2653	103	38	(	(	PUNCT
dpc-2653	103	39	nsclc	nsclc	NOUN
dpc-2653	103	40	)	)	PUNCT
dpc-2653	103	41	,	,	PUNCT
dpc-2653	103	42	and	and	CCONJ
dpc-2653	103	43	breast	breast	NOUN
dpc-2653	103	44	,	,	PUNCT
dpc-2653	103	45	head	head	NOUN
dpc-2653	103	46	,	,	PUNCT
dpc-2653	103	47	and	and	CCONJ
dpc-2653	103	48	neck	neck	NOUN
dpc-2653	103	49	carcinoma	carcinoma	NOUN
dpc-2653	103	50	.	.	PUNCT
dpc-2653	104	1	uncommon	uncommon	ADJ
dpc-2653	104	2	reported	report	VERB
dpc-2653	104	3	nail	nail	NOUN
dpc-2653	104	4	reactions	reaction	NOUN
dpc-2653	104	5	to	to	ADP
dpc-2653	104	6	pemetrexed	pemetrexed	NOUN
dpc-2653	104	7	include	include	VERB
dpc-2653	104	8	melanonychia	melanonychia	NOUN
dpc-2653	104	9	and	and	CCONJ
dpc-2653	104	10	onycholysis	onycholysis	NOUN
dpc-2653	105	1	[	[	X
dpc-2653	105	2	14	14	NUM
dpc-2653	105	3	]	]	X
dpc-2653	105	4	(	(	PUNCT
dpc-2653	105	5	table	table	NOUN
dpc-2653	105	6	2	2	NUM
dpc-2653	105	7	)	)	PUNCT
dpc-2653	105	8	.	.	PUNCT
dpc-2653	106	1	fluorouracil	fluorouracil	NOUN
dpc-2653	106	2	:	:	PUNCT
dpc-2653	106	3	5	5	NUM
dpc-2653	106	4	-	-	PUNCT
dpc-2653	106	5	fluorouracil	fluorouracil	NOUN
dpc-2653	106	6	,	,	PUNCT
dpc-2653	106	7	capecitabine	capecitabine	NOUN
dpc-2653	106	8	and	and	CCONJ
dpc-2653	106	9	tegafur	tegafur	NOUN
dpc-2653	106	10	5	5	NUM
dpc-2653	106	11	-	-	PUNCT
dpc-2653	106	12	fluorouracil	fluorouracil	NOUN
dpc-2653	106	13	(	(	PUNCT
dpc-2653	106	14	5	5	NUM
dpc-2653	106	15	-	-	PUNCT
dpc-2653	106	16	fu	fu	NOUN
dpc-2653	106	17	)	)	PUNCT
dpc-2653	106	18	is	be	AUX
dpc-2653	106	19	a	a	DET
dpc-2653	106	20	pyrimidine	pyrimidine	NOUN
dpc-2653	106	21	analog	analog	NOUN
dpc-2653	106	22	that	that	PRON
dpc-2653	106	23	inhibits	inhibit	VERB
dpc-2653	106	24	the	the	DET
dpc-2653	106	25	enzyme	enzyme	NOUN
dpc-2653	106	26	thymidylate	thymidylate	NOUN
dpc-2653	106	27	synthase	synthase	NOUN
dpc-2653	106	28	,	,	PUNCT
dpc-2653	106	29	thereby	thereby	ADV
dpc-2653	106	30	interrupting	interrupt	VERB
dpc-2653	106	31	thymidine	thymidine	ADJ
dpc-2653	106	32	synthesis	synthesis	NOUN
dpc-2653	106	33	required	require	VERB
dpc-2653	106	34	for	for	ADP
dpc-2653	106	35	dna	dna	NOUN
dpc-2653	106	36	replication	replication	NOUN
dpc-2653	106	37	,	,	PUNCT
dpc-2653	106	38	and	and	CCONJ
dpc-2653	106	39	can	can	AUX
dpc-2653	106	40	cause	cause	VERB
dpc-2653	106	41	myelosuppression	myelosuppression	NOUN
dpc-2653	106	42	,	,	PUNCT
dpc-2653	106	43	diarrhea	diarrhea	PROPN
dpc-2653	106	44	,	,	PUNCT
dpc-2653	106	45	mucositis	mucositis	NOUN
dpc-2653	106	46	,	,	PUNCT
dpc-2653	106	47	and	and	CCONJ
dpc-2653	106	48	dermatitis	dermatitis	NOUN
dpc-2653	106	49	[	[	X
dpc-2653	106	50	12	12	NUM
dpc-2653	106	51	]	]	PUNCT
dpc-2653	106	52	.	.	PUNCT
dpc-2653	107	1	capecitabine	capecitabine	PROPN
dpc-2653	107	2	and	and	CCONJ
dpc-2653	107	3	tegafur	tegafur	NOUN
dpc-2653	107	4	are	be	AUX
dpc-2653	107	5	orally	orally	ADV
dpc-2653	107	6	administered	administer	VERB
dpc-2653	107	7	prodrugs	prodrug	NOUN
dpc-2653	107	8	especially	especially	ADV
dpc-2653	107	9	used	use	VERB
dpc-2653	107	10	for	for	ADP
dpc-2653	107	11	colon	colon	NOUN
dpc-2653	107	12	and	and	CCONJ
dpc-2653	107	13	gastrointestinal	gastrointestinal	ADJ
dpc-2653	107	14	neoplasms	neoplasm	NOUN
dpc-2653	107	15	.	.	PUNCT
dpc-2653	108	1	they	they	PRON
dpc-2653	108	2	are	be	AUX
dpc-2653	108	3	designed	design	VERB
dpc-2653	108	4	to	to	PART
dpc-2653	108	5	be	be	AUX
dpc-2653	108	6	well	well	ADV
dpc-2653	108	7	absorbed	absorb	VERB
dpc-2653	108	8	from	from	ADP
dpc-2653	108	9	the	the	DET
dpc-2653	108	10	gastrointestinal	gastrointestinal	ADJ
dpc-2653	108	11	tract	tract	NOUN
dpc-2653	108	12	and	and	CCONJ
dpc-2653	108	13	converted	convert	VERB
dpc-2653	108	14	to	to	ADP
dpc-2653	108	15	5	5	NUM
dpc-2653	108	16	-	-	PUNCT
dpc-2653	108	17	fu	fu	NOUN
dpc-2653	108	18	in	in	ADP
dpc-2653	108	19	the	the	DET
dpc-2653	108	20	liver	liver	NOUN
dpc-2653	108	21	or	or	CCONJ
dpc-2653	108	22	within	within	ADP
dpc-2653	108	23	the	the	DET
dpc-2653	108	24	tumor	tumor	NOUN
dpc-2653	108	25	at	at	ADP
dpc-2653	108	26	lower	low	ADJ
dpc-2653	108	27	concentrations	concentration	NOUN
dpc-2653	108	28	than	than	ADP
dpc-2653	108	29	5	5	NUM
dpc-2653	108	30	-	-	PUNCT
dpc-2653	108	31	fu	fu	NOUN
dpc-2653	108	32	intravenous	intravenous	ADJ
dpc-2653	108	33	dosages	dosage	NOUN
dpc-2653	108	34	,	,	PUNCT
dpc-2653	108	35	thereby	thereby	ADV
dpc-2653	108	36	minimizing	minimize	VERB
dpc-2653	108	37	toxicity	toxicity	NOUN
dpc-2653	108	38	[	[	X
dpc-2653	108	39	15	15	NUM
dpc-2653	108	40	]	]	PUNCT
dpc-2653	108	41	.	.	PUNCT
dpc-2653	109	1	in	in	ADP
dpc-2653	109	2	the	the	DET
dpc-2653	109	3	nails	nail	NOUN
dpc-2653	109	4	,	,	PUNCT
dpc-2653	109	5	5	5	NUM
dpc-2653	109	6	-	-	PUNCT
dpc-2653	109	7	fu	fu	NOUN
dpc-2653	109	8	may	may	AUX
dpc-2653	109	9	cause	cause	VERB
dpc-2653	109	10	diffuse	diffuse	NOUN
dpc-2653	109	11	melanonychia	melanonychia	NOUN
dpc-2653	109	12	,	,	PUNCT
dpc-2653	109	13	transverse	transverse	NOUN
dpc-2653	109	14	bands	band	NOUN
dpc-2653	109	15	,	,	PUNCT
dpc-2653	109	16	or	or	CCONJ
dpc-2653	109	17	half	half	NOUN
dpc-2653	109	18	and	and	CCONJ
dpc-2653	109	19	half	half	ADJ
dpc-2653	109	20	-	-	PUNCT
dpc-2653	109	21	like	like	ADJ
dpc-2653	109	22	nails	nail	NOUN
dpc-2653	109	23	(	(	PUNCT
dpc-2653	109	24	lindsay	lindsay	PROPN
dpc-2653	109	25	nails	nails	PROPN
dpc-2653	109	26	)	)	PUNCT
dpc-2653	109	27	,	,	PUNCT
dpc-2653	109	28	while	while	SCONJ
dpc-2653	109	29	there	there	PRON
dpc-2653	109	30	have	have	AUX
dpc-2653	109	31	also	also	ADV
dpc-2653	109	32	been	be	AUX
dpc-2653	109	33	reports	report	NOUN
dpc-2653	109	34	of	of	ADP
dpc-2653	109	35	onycholysis	onycholysis	NOUN
dpc-2653	109	36	,	,	PUNCT
dpc-2653	109	37	paronychia	paronychia	NOUN
dpc-2653	109	38	,	,	PUNCT
dpc-2653	109	39	and	and	CCONJ
dpc-2653	109	40	thickening	thickening	NOUN
dpc-2653	109	41	of	of	ADP
dpc-2653	109	42	the	the	DET
dpc-2653	109	43	nail	nail	NOUN
dpc-2653	109	44	with	with	ADP
dpc-2653	109	45	its	its	PRON
dpc-2653	109	46	use	use	NOUN
dpc-2653	109	47	[	[	X
dpc-2653	109	48	16	16	NUM
dpc-2653	109	49	]	]	PUNCT
dpc-2653	109	50	.	.	PUNCT
dpc-2653	110	1	capecitabine	capecitabine	PROPN
dpc-2653	110	2	and	and	CCONJ
dpc-2653	110	3	tegafur	tegafur	NOUN
dpc-2653	110	4	also	also	ADV
dpc-2653	110	5	cause	cause	VERB
dpc-2653	110	6	longitudinal	longitudinal	ADJ
dpc-2653	110	7	melanonychia	melanonychia	NOUN
dpc-2653	111	1	[	[	X
dpc-2653	111	2	16	16	NUM
dpc-2653	111	3	]	]	X
dpc-2653	111	4	;	;	PUNCT
dpc-2653	111	5	however	however	ADV
dpc-2653	111	6	,	,	PUNCT
dpc-2653	111	7	onycholysis	onycholysis	NOUN
dpc-2653	111	8	and	and	CCONJ
dpc-2653	111	9	onychomadesis	onychomadesis	NOUN
dpc-2653	111	10	have	have	AUX
dpc-2653	111	11	only	only	ADV
dpc-2653	111	12	been	be	AUX
dpc-2653	111	13	seen	see	VERB
dpc-2653	111	14	with	with	ADP
dpc-2653	111	15	capecitabine	capecitabine	NOUN
dpc-2653	111	16	[	[	X
dpc-2653	111	17	12	12	NUM
dpc-2653	111	18	]	]	PUNCT
dpc-2653	111	19	(	(	PUNCT
dpc-2653	111	20	table	table	NOUN
dpc-2653	111	21	2	2	NUM
dpc-2653	111	22	)	)	PUNCT
dpc-2653	111	23	.	.	PUNCT
dpc-2653	112	1	antitumor	antitumor	PROPN
dpc-2653	112	2	antibiotics	antibiotic	NOUN
dpc-2653	112	3	anthracyclines	anthracycline	NOUN
dpc-2653	112	4	:	:	PUNCT
dpc-2653	112	5	doxorubicin	doxorubicin	PROPN
dpc-2653	112	6	and	and	CCONJ
dpc-2653	112	7	daunorubicin	daunorubicin	VERB
dpc-2653	112	8	the	the	DET
dpc-2653	112	9	anthracyclines	anthracycline	NOUN
dpc-2653	112	10	doxorubicin	doxorubicin	PROPN
dpc-2653	112	11	and	and	CCONJ
dpc-2653	112	12	daunorubicin	daunorubicin	NOUN
dpc-2653	112	13	are	be	AUX
dpc-2653	112	14	derived	derive	VERB
dpc-2653	112	15	from	from	ADP
dpc-2653	112	16	the	the	DET
dpc-2653	112	17	bacterium	bacterium	NOUN
dpc-2653	112	18	streptomyces	streptomyce	NOUN
dpc-2653	112	19	peucetius	peucetius	NOUN
dpc-2653	112	20	var	var	NOUN
dpc-2653	112	21	.	.	PUNCT
dpc-2653	113	1	caesius	caesius	PROPN
dpc-2653	113	2	6	6	NUM
dpc-2653	113	3	review	review	NOUN
dpc-2653	113	4	|	|	ADV
dpc-2653	113	5	dermatol	dermatol	ADJ
dpc-2653	113	6	pract	pract	NOUN
dpc-2653	113	7	concept	concept	NOUN
dpc-2653	113	8	.	.	PUNCT
dpc-2653	114	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	114	2	ii	ii	NOUN
dpc-2653	114	3	inhibitors	inhibitor	NOUN
dpc-2653	114	4	frequently	frequently	ADV
dpc-2653	114	5	induce	induce	VERB
dpc-2653	114	6	rearrangements	rearrangement	NOUN
dpc-2653	114	7	of	of	ADP
dpc-2653	114	8	the	the	DET
dpc-2653	114	9	mixed	mixed	ADJ
dpc-2653	114	10	lineage	lineage	NOUN
dpc-2653	114	11	leukemia	leukemia	NOUN
dpc-2653	114	12	gene	gene	NOUN
dpc-2653	114	13	and	and	CCONJ
dpc-2653	114	14	can	can	AUX
dpc-2653	114	15	cause	cause	VERB
dpc-2653	114	16	a	a	DET
dpc-2653	114	17	secondary	secondary	ADJ
dpc-2653	114	18	leukemia	leukemia	NOUN
dpc-2653	114	19	side	side	NOUN
dpc-2653	114	20	effect	effect	NOUN
dpc-2653	114	21	[	[	X
dpc-2653	114	22	36	36	NUM
dpc-2653	114	23	]	]	PUNCT
dpc-2653	114	24	.	.	PUNCT
dpc-2653	115	1	etoposide	etoposide	NOUN
dpc-2653	115	2	has	have	AUX
dpc-2653	115	3	been	be	AUX
dpc-2653	115	4	approved	approve	VERB
dpc-2653	115	5	by	by	ADP
dpc-2653	115	6	the	the	DET
dpc-2653	115	7	us	us	PROPN
dpc-2653	115	8	food	food	NOUN
dpc-2653	115	9	and	and	CCONJ
dpc-2653	115	10	drug	drug	PROPN
dpc-2653	115	11	administration	administration	NOUN
dpc-2653	115	12	to	to	PART
dpc-2653	115	13	be	be	AUX
dpc-2653	115	14	used	use	VERB
dpc-2653	115	15	in	in	ADP
dpc-2653	115	16	combination	combination	NOUN
dpc-2653	115	17	with	with	ADP
dpc-2653	115	18	other	other	ADJ
dpc-2653	115	19	medications	medication	NOUN
dpc-2653	115	20	to	to	PART
dpc-2653	115	21	treat	treat	VERB
dpc-2653	115	22	small	small	ADJ
dpc-2653	115	23	cell	cell	NOUN
dpc-2653	115	24	lung	lung	NOUN
dpc-2653	115	25	cancer	cancer	NOUN
dpc-2653	115	26	and	and	CCONJ
dpc-2653	115	27	testicular	testicular	ADJ
dpc-2653	115	28	cancer	cancer	NOUN
dpc-2653	115	29	.	.	PUNCT
dpc-2653	116	1	it	it	PRON
dpc-2653	116	2	is	be	AUX
dpc-2653	116	3	a	a	DET
dpc-2653	116	4	derivative	derivative	NOUN
dpc-2653	116	5	of	of	ADP
dpc-2653	116	6	podophyllotoxin	podophyllotoxin	PROPN
dpc-2653	116	7	.	.	PUNCT
dpc-2653	117	1	it	it	PRON
dpc-2653	117	2	is	be	AUX
dpc-2653	117	3	typically	typically	ADV
dpc-2653	117	4	taken	take	VERB
dpc-2653	117	5	orally	orally	ADV
dpc-2653	117	6	,	,	PUNCT
dpc-2653	117	7	but	but	CCONJ
dpc-2653	117	8	can	can	AUX
dpc-2653	117	9	also	also	ADV
dpc-2653	117	10	be	be	AUX
dpc-2653	117	11	administered	administer	VERB
dpc-2653	117	12	intravenously	intravenously	ADV
dpc-2653	117	13	,	,	PUNCT
dpc-2653	117	14	though	though	SCONJ
dpc-2653	117	15	care	care	NOUN
dpc-2653	117	16	must	must	AUX
dpc-2653	117	17	be	be	AUX
dpc-2653	117	18	used	use	VERB
dpc-2653	117	19	to	to	PART
dpc-2653	117	20	prevent	prevent	VERB
dpc-2653	117	21	extravasation	extravasation	NOUN
dpc-2653	117	22	because	because	SCONJ
dpc-2653	117	23	it	it	PRON
dpc-2653	117	24	is	be	AUX
dpc-2653	117	25	an	an	DET
dpc-2653	117	26	irritant	irritant	NOUN
dpc-2653	117	27	and	and	CCONJ
dpc-2653	117	28	can	can	AUX
dpc-2653	117	29	cause	cause	VERB
dpc-2653	117	30	tissue	tissue	NOUN
dpc-2653	117	31	damage	damage	NOUN
dpc-2653	117	32	.	.	PUNCT
dpc-2653	118	1	nail	nail	NOUN
dpc-2653	118	2	toxic	toxic	ADJ
dpc-2653	118	3	side	side	NOUN
dpc-2653	118	4	effect	effect	NOUN
dpc-2653	118	5	caused	cause	VERB
dpc-2653	118	6	by	by	ADP
dpc-2653	118	7	etoposide	etoposide	NOUN
dpc-2653	118	8	is	be	AUX
dpc-2653	118	9	paronychia	paronychia	VERB
dpc-2653	118	10	[	[	X
dpc-2653	118	11	12	12	NUM
dpc-2653	118	12	]	]	PUNCT
dpc-2653	118	13	(	(	PUNCT
dpc-2653	118	14	table	table	NOUN
dpc-2653	118	15	2	2	NUM
dpc-2653	118	16	)	)	PUNCT
dpc-2653	118	17	.	.	PUNCT
dpc-2653	119	1	targeted	target	VERB
dpc-2653	119	2	biologic	biologic	NOUN
dpc-2653	119	3	drugs	drug	NOUN
dpc-2653	119	4	(	(	PUNCT
dpc-2653	119	5	figure	figure	NOUN
dpc-2653	119	6	2	2	NUM
dpc-2653	119	7	)	)	PUNCT
dpc-2653	119	8	targeted	target	VERB
dpc-2653	119	9	cancer	cancer	NOUN
dpc-2653	119	10	therapies	therapy	NOUN
dpc-2653	119	11	are	be	AUX
dpc-2653	119	12	drugs	drug	NOUN
dpc-2653	119	13	that	that	PRON
dpc-2653	119	14	selectively	selectively	ADV
dpc-2653	119	15	block	block	VERB
dpc-2653	119	16	specific	specific	ADJ
dpc-2653	119	17	parts	part	NOUN
dpc-2653	119	18	of	of	ADP
dpc-2653	119	19	cancer	cancer	NOUN
dpc-2653	119	20	cells	cell	NOUN
dpc-2653	119	21	,	,	PUNCT
dpc-2653	119	22	such	such	ADJ
dpc-2653	119	23	as	as	ADP
dpc-2653	119	24	proteins	protein	NOUN
dpc-2653	119	25	or	or	CCONJ
dpc-2653	119	26	genes	gene	NOUN
dpc-2653	119	27	,	,	PUNCT
dpc-2653	119	28	that	that	PRON
dpc-2653	119	29	help	help	VERB
dpc-2653	119	30	cancers	cancer	NOUN
dpc-2653	119	31	grow	grow	VERB
dpc-2653	119	32	and	and	CCONJ
dpc-2653	119	33	spread	spread	VERB
dpc-2653	119	34	.	.	PUNCT
dpc-2653	120	1	targeted	target	VERB
dpc-2653	120	2	biologic	biologic	NOUN
dpc-2653	120	3	therapies	therapy	NOUN
dpc-2653	120	4	are	be	AUX
dpc-2653	120	5	well	well	ADV
dpc-2653	120	6	-	-	PUNCT
dpc-2653	120	7	known	know	VERB
dpc-2653	120	8	causing	cause	VERB
dpc-2653	120	9	factors	factor	NOUN
dpc-2653	120	10	of	of	ADP
dpc-2653	120	11	cutaneous	cutaneous	ADJ
dpc-2653	120	12	adverse	adverse	ADJ
dpc-2653	120	13	effects	effect	NOUN
dpc-2653	120	14	,	,	PUNCT
dpc-2653	120	15	including	include	VERB
dpc-2653	120	16	changes	change	NOUN
dpc-2653	120	17	in	in	ADP
dpc-2653	120	18	the	the	DET
dpc-2653	120	19	nail	nail	NOUN
dpc-2653	120	20	apparatus	apparatus	NOUN
dpc-2653	120	21	[	[	X
dpc-2653	120	22	37	37	NUM
dpc-2653	120	23	,	,	PUNCT
dpc-2653	120	24	38	38	NUM
dpc-2653	120	25	]	]	PUNCT
dpc-2653	120	26	.	.	PUNCT
dpc-2653	121	1	cutaneous	cutaneous	ADJ
dpc-2653	121	2	and	and	CCONJ
dpc-2653	121	3	nail	nail	NOUN
dpc-2653	121	4	reactions	reaction	NOUN
dpc-2653	121	5	may	may	AUX
dpc-2653	121	6	be	be	AUX
dpc-2653	121	7	attributed	attribute	VERB
dpc-2653	121	8	to	to	ADP
dpc-2653	121	9	the	the	DET
dpc-2653	121	10	mode	mode	NOUN
dpc-2653	121	11	of	of	ADP
dpc-2653	121	12	action	action	NOUN
dpc-2653	121	13	of	of	ADP
dpc-2653	121	14	these	these	DET
dpc-2653	121	15	regimens	regimen	NOUN
dpc-2653	121	16	that	that	PRON
dpc-2653	121	17	target	target	VERB
dpc-2653	121	18	specific	specific	ADJ
dpc-2653	121	19	molecules	molecule	NOUN
dpc-2653	121	20	that	that	PRON
dpc-2653	121	21	are	be	AUX
dpc-2653	121	22	also	also	ADV
dpc-2653	121	23	expressed	express	VERB
dpc-2653	121	24	in	in	ADP
dpc-2653	121	25	the	the	DET
dpc-2653	121	26	skin	skin	NOUN
dpc-2653	121	27	and	and	CCONJ
dpc-2653	121	28	appendageal	appendageal	NOUN
dpc-2653	121	29	epithelium	epithelium	NOUN
dpc-2653	121	30	.	.	PUNCT
dpc-2653	122	1	egfr	egfr	ADJ
dpc-2653	122	2	-	-	PUNCT
dpc-2653	122	3	inhibitors	inhibitor	NOUN
dpc-2653	122	4	epidermal	epidermal	ADJ
dpc-2653	122	5	growth	growth	NOUN
dpc-2653	122	6	factor	factor	NOUN
dpc-2653	122	7	receptor	receptor	NOUN
dpc-2653	122	8	inhibitors	inhibitor	NOUN
dpc-2653	122	9	(	(	PUNCT
dpc-2653	122	10	gefitinib	gefitinib	NOUN
dpc-2653	122	11	,	,	PUNCT
dpc-2653	122	12	erlotinib	erlotinib	NOUN
dpc-2653	122	13	,	,	PUNCT
dpc-2653	122	14	cetuximab	cetuximab	NOUN
dpc-2653	122	15	,	,	PUNCT
dpc-2653	122	16	panitumumab	panitumumab	NOUN
dpc-2653	122	17	)	)	PUNCT
dpc-2653	122	18	block	block	VERB
dpc-2653	122	19	the	the	DET
dpc-2653	122	20	signal	signal	ADJ
dpc-2653	122	21	transduction	transduction	NOUN
dpc-2653	122	22	pathway	pathway	NOUN
dpc-2653	122	23	,	,	PUNCT
dpc-2653	122	24	needed	need	VERB
dpc-2653	122	25	for	for	ADP
dpc-2653	122	26	cell	cell	NOUN
dpc-2653	122	27	proliferation	proliferation	NOUN
dpc-2653	122	28	,	,	PUNCT
dpc-2653	122	29	migration	migration	NOUN
dpc-2653	122	30	and	and	CCONJ
dpc-2653	122	31	angiogenesis	angiogenesis	NOUN
dpc-2653	122	32	of	of	ADP
dpc-2653	122	33	tumor	tumor	NOUN
dpc-2653	122	34	cells	cell	NOUN
dpc-2653	122	35	[	[	X
dpc-2653	122	36	3740	3740	NUM
dpc-2653	122	37	]	]	PUNCT
dpc-2653	122	38	.	.	PUNCT
dpc-2653	123	1	gefitinib	gefitinib	NOUN
dpc-2653	123	2	and	and	CCONJ
dpc-2653	123	3	erlotinib	erlotinib	NOUN
dpc-2653	123	4	are	be	AUX
dpc-2653	123	5	orally	orally	ADV
dpc-2653	123	6	administered	administer	VERB
dpc-2653	123	7	egfr	egfr	ADJ
dpc-2653	123	8	tyrosine	tyrosine	PROPN
dpc-2653	123	9	kinase	kinase	PROPN
dpc-2653	123	10	inhibitors	inhibitor	NOUN
dpc-2653	123	11	,	,	PUNCT
dpc-2653	123	12	whilst	whilst	SCONJ
dpc-2653	123	13	cetuximab	cetuximab	NOUN
dpc-2653	123	14	and	and	CCONJ
dpc-2653	123	15	panitumumab	panitumumab	NOUN
dpc-2653	123	16	are	be	AUX
dpc-2653	123	17	humanized	humanize	VERB
dpc-2653	123	18	monoclonal	monoclonal	NOUN
dpc-2653	123	19	antibodies	antibody	NOUN
dpc-2653	123	20	that	that	PRON
dpc-2653	123	21	are	be	AUX
dpc-2653	123	22	given	give	VERB
dpc-2653	123	23	intravenously	intravenously	ADV
dpc-2653	123	24	.	.	PUNCT
dpc-2653	124	1	these	these	DET
dpc-2653	124	2	regimens	regimen	NOUN
dpc-2653	124	3	are	be	AUX
dpc-2653	124	4	used	use	VERB
dpc-2653	124	5	for	for	ADP
dpc-2653	124	6	colorectal	colorectal	ADJ
dpc-2653	124	7	cancer	cancer	NOUN
dpc-2653	124	8	,	,	PUNCT
dpc-2653	124	9	breast	breast	NOUN
dpc-2653	124	10	cancer	cancer	NOUN
dpc-2653	124	11	,	,	PUNCT
dpc-2653	124	12	non	non	ADJ
dpc-2653	124	13	-	-	ADJ
dpc-2653	124	14	small	small	ADJ
dpc-2653	124	15	cell	cell	NOUN
dpc-2653	124	16	lung	lung	NOUN
dpc-2653	124	17	cancer	cancer	NOUN
dpc-2653	124	18	(	(	PUNCT
dpc-2653	124	19	nsclc	nsclc	NOUN
dpc-2653	124	20	)	)	PUNCT
dpc-2653	124	21	,	,	PUNCT
dpc-2653	124	22	pancreatic	pancreatic	ADJ
dpc-2653	124	23	cancer	cancer	NOUN
dpc-2653	124	24	,	,	PUNCT
dpc-2653	124	25	and	and	CCONJ
dpc-2653	124	26	head	head	NOUN
dpc-2653	124	27	and	and	CCONJ
dpc-2653	124	28	neck	neck	VERB
dpc-2653	124	29	squamous	squamous	ADJ
dpc-2653	124	30	cell	cell	NOUN
dpc-2653	124	31	carcinoma	carcinoma	NOUN
dpc-2653	124	32	(	(	PUNCT
dpc-2653	124	33	scc	scc	NOUN
dpc-2653	124	34	)	)	PUNCT
dpc-2653	125	1	[	[	X
dpc-2653	125	2	3840	3840	NUM
dpc-2653	125	3	]	]	PUNCT
dpc-2653	125	4	.	.	PUNCT
dpc-2653	126	1	a	a	DET
dpc-2653	126	2	common	common	ADJ
dpc-2653	126	3	nail	nail	NOUN
dpc-2653	126	4	reaction	reaction	NOUN
dpc-2653	126	5	in	in	ADP
dpc-2653	126	6	the	the	DET
dpc-2653	126	7	context	context	NOUN
dpc-2653	126	8	of	of	ADP
dpc-2653	126	9	egfr	egfr	ADJ
dpc-2653	126	10	inhibition	inhibition	NOUN
dpc-2653	126	11	is	be	AUX
dpc-2653	126	12	paronychia	paronychia	VERB
dpc-2653	126	13	,	,	PUNCT
dpc-2653	126	14	representing	represent	VERB
dpc-2653	126	15	the	the	DET
dpc-2653	126	16	second	second	ADJ
dpc-2653	126	17	most	most	ADV
dpc-2653	126	18	frequent	frequent	ADJ
dpc-2653	126	19	skin	skin	NOUN
dpc-2653	126	20	toxicity	toxicity	NOUN
dpc-2653	126	21	induced	induce	VERB
dpc-2653	126	22	by	by	ADP
dpc-2653	126	23	egfr	egfr	NOUN
dpc-2653	126	24	after	after	ADP
dpc-2653	126	25	papulopustular	papulopustular	ADJ
dpc-2653	126	26	eruption	eruption	NOUN
dpc-2653	126	27	[	[	X
dpc-2653	126	28	41	41	NUM
dpc-2653	126	29	]	]	PUNCT
dpc-2653	126	30	.	.	PUNCT
dpc-2653	127	1	it	it	PRON
dpc-2653	127	2	involves	involve	VERB
dpc-2653	127	3	the	the	DET
dpc-2653	127	4	nails	nail	NOUN
dpc-2653	127	5	and	and	CCONJ
dpc-2653	127	6	the	the	DET
dpc-2653	127	7	digits	digit	NOUN
dpc-2653	127	8	,	,	PUNCT
dpc-2653	127	9	with	with	ADP
dpc-2653	127	10	the	the	DET
dpc-2653	127	11	first	first	ADJ
dpc-2653	127	12	digit	digit	NOUN
dpc-2653	127	13	being	be	AUX
dpc-2653	127	14	the	the	DET
dpc-2653	127	15	site	site	NOUN
dpc-2653	127	16	most	most	ADV
dpc-2653	127	17	commonly	commonly	ADV
dpc-2653	127	18	affected	affect	VERB
dpc-2653	127	19	.	.	PUNCT
dpc-2653	128	1	other	other	ADJ
dpc-2653	128	2	ungual	ungual	ADJ
dpc-2653	128	3	adverse	adverse	ADJ
dpc-2653	128	4	reactions	reaction	NOUN
dpc-2653	128	5	include	include	VERB
dpc-2653	128	6	discoloration	discoloration	NOUN
dpc-2653	128	7	,	,	PUNCT
dpc-2653	128	8	pitting	pitting	NOUN
dpc-2653	128	9	,	,	PUNCT
dpc-2653	128	10	nail	nail	NOUN
dpc-2653	128	11	thinning	thinning	NOUN
dpc-2653	128	12	/	/	SYM
dpc-2653	128	13	fragility	fragility	NOUN
dpc-2653	128	14	(	(	PUNCT
dpc-2653	128	15	inhibition	inhibition	NOUN
dpc-2653	128	16	of	of	ADP
dpc-2653	128	17	nail	nail	NOUN
dpc-2653	128	18	matrix	matrix	NOUN
dpc-2653	128	19	keratinocytes	keratinocyte	NOUN
dpc-2653	128	20	)	)	PUNCT
dpc-2653	128	21	,	,	PUNCT
dpc-2653	128	22	periungual	periungual	ADJ
dpc-2653	128	23	pyogenic	pyogenic	ADJ
dpc-2653	128	24	granuloma	granuloma	NOUN
dpc-2653	128	25	(	(	PUNCT
dpc-2653	128	26	an	an	DET
dpc-2653	128	27	overgrowth	overgrowth	NOUN
dpc-2653	128	28	of	of	ADP
dpc-2653	128	29	granulation	granulation	ADJ
dpc-2653	128	30	tissue	tissue	NOUN
dpc-2653	128	31	and	and	CCONJ
dpc-2653	128	32	a	a	DET
dpc-2653	128	33	formation	formation	NOUN
dpc-2653	128	34	of	of	ADP
dpc-2653	128	35	painful	painful	ADJ
dpc-2653	128	36	,	,	PUNCT
dpc-2653	128	37	bleeding	bleed	VERB
dpc-2653	128	38	nodule	nodule	NOUN
dpc-2653	128	39	)	)	PUNCT
dpc-2653	128	40	,	,	PUNCT
dpc-2653	128	41	cracked	crack	VERB
dpc-2653	128	42	and	and	CCONJ
dpc-2653	128	43	swollen	swollen	ADJ
dpc-2653	128	44	nail	nail	NOUN
dpc-2653	128	45	folds	fold	NOUN
dpc-2653	128	46	and	and	CCONJ
dpc-2653	128	47	cuticles	cuticle	NOUN
dpc-2653	128	48	,	,	PUNCT
dpc-2653	128	49	partial	partial	ADJ
dpc-2653	128	50	or	or	CCONJ
dpc-2653	128	51	complete	complete	ADJ
dpc-2653	128	52	loss	loss	NOUN
dpc-2653	128	53	of	of	ADP
dpc-2653	128	54	nails	nail	NOUN
dpc-2653	128	55	and	and	CCONJ
dpc-2653	128	56	ingrowth	ingrowth	NOUN
dpc-2653	128	57	of	of	ADP
dpc-2653	128	58	nails	nail	NOUN
dpc-2653	128	59	[	[	X
dpc-2653	128	60	37	37	NUM
dpc-2653	128	61	,	,	PUNCT
dpc-2653	128	62	38	38	NUM
dpc-2653	128	63	]	]	PUNCT
dpc-2653	128	64	(	(	PUNCT
dpc-2653	128	65	table	table	NOUN
dpc-2653	128	66	3	3	NUM
dpc-2653	128	67	)	)	PUNCT
dpc-2653	128	68	.	.	PUNCT
dpc-2653	129	1	the	the	DET
dpc-2653	129	2	aforementioned	aforementioned	ADJ
dpc-2653	129	3	alterations	alteration	NOUN
dpc-2653	129	4	may	may	AUX
dpc-2653	129	5	appear	appear	VERB
dpc-2653	129	6	1	1	NUM
dpc-2653	129	7	to	to	PART
dpc-2653	129	8	2	2	NUM
dpc-2653	129	9	months	month	NOUN
dpc-2653	129	10	after	after	ADP
dpc-2653	129	11	treatment	treatment	NOUN
dpc-2653	129	12	initiation	initiation	NOUN
dpc-2653	129	13	and	and	CCONJ
dpc-2653	129	14	affect	affect	VERB
dpc-2653	129	15	about	about	ADV
dpc-2653	129	16	15	15	NUM
dpc-2653	129	17	%	%	NOUN
dpc-2653	129	18	of	of	ADP
dpc-2653	129	19	patients	patient	NOUN
dpc-2653	129	20	[	[	X
dpc-2653	129	21	38	38	NUM
dpc-2653	129	22	]	]	PUNCT
dpc-2653	129	23	.	.	PUNCT
dpc-2653	130	1	secondary	secondary	ADJ
dpc-2653	130	2	infection	infection	NOUN
dpc-2653	130	3	is	be	AUX
dpc-2653	130	4	not	not	PART
dpc-2653	130	5	unusual	unusual	ADJ
dpc-2653	130	6	and	and	CCONJ
dpc-2653	130	7	in	in	ADP
dpc-2653	130	8	this	this	DET
dpc-2653	130	9	scenario	scenario	NOUN
dpc-2653	130	10	,	,	PUNCT
dpc-2653	130	11	a	a	DET
dpc-2653	130	12	culture	culture	NOUN
dpc-2653	130	13	swab	swab	NOUN
dpc-2653	130	14	is	be	AUX
dpc-2653	130	15	recommended	recommend	VERB
dpc-2653	130	16	.	.	PUNCT
dpc-2653	131	1	in	in	ADP
dpc-2653	131	2	patients	patient	NOUN
dpc-2653	131	3	treated	treat	VERB
dpc-2653	131	4	with	with	ADP
dpc-2653	131	5	cetuximab	cetuximab	NOUN
dpc-2653	131	6	that	that	PRON
dpc-2653	131	7	developed	develop	VERB
dpc-2653	131	8	paronychia	paronychia	PROPN
dpc-2653	131	9	,	,	PUNCT
dpc-2653	131	10	staphylococcus	staphylococcus	NOUN
dpc-2653	131	11	aureus	aureus	NOUN
dpc-2653	131	12	was	be	AUX
dpc-2653	131	13	found	find	VERB
dpc-2653	131	14	in	in	ADP
dpc-2653	131	15	23	23	NUM
dpc-2653	131	16	%	%	NOUN
dpc-2653	131	17	,	,	PUNCT
dpc-2653	131	18	while	while	SCONJ
dpc-2653	131	19	31	31	NUM
dpc-2653	131	20	%	%	NOUN
dpc-2653	131	21	had	have	VERB
dpc-2653	131	22	coagulase	coagulase	NOUN
dpc-2653	131	23	-	-	PUNCT
dpc-2653	131	24	negative	negative	ADJ
dpc-2653	131	25	,	,	PUNCT
dpc-2653	131	26	gram	gram	NOUN
dpc-2653	131	27	(	(	PUNCT
dpc-2653	131	28	+	+	NOUN
dpc-2653	131	29	)	)	PUNCT
dpc-2653	131	30	bacteria	bacteria	NOUN
dpc-2653	131	31	(	(	PUNCT
dpc-2653	131	32	nosocomial	nosocomial	ADJ
dpc-2653	131	33	colonization	colonization	NOUN
dpc-2653	131	34	)	)	PUNCT
dpc-2653	132	1	[	[	X
dpc-2653	132	2	37	37	NUM
dpc-2653	132	3	,	,	PUNCT
dpc-2653	132	4	38	38	NUM
dpc-2653	132	5	]	]	PUNCT
dpc-2653	132	6	.	.	PUNCT
dpc-2653	133	1	prevention	prevention	NOUN
dpc-2653	133	2	of	of	ADP
dpc-2653	133	3	superinfection	superinfection	NOUN
dpc-2653	133	4	was	be	AUX
dpc-2653	133	5	achieved	achieve	VERB
dpc-2653	133	6	cancer	cancer	NOUN
dpc-2653	133	7	,	,	PUNCT
dpc-2653	133	8	and	and	CCONJ
dpc-2653	133	9	advanced	advanced	ADJ
dpc-2653	133	10	head	head	NOUN
dpc-2653	133	11	and	and	CCONJ
dpc-2653	133	12	neck	neck	VERB
dpc-2653	133	13	squamous	squamous	ADJ
dpc-2653	133	14	cancer	cancer	NOUN
dpc-2653	134	1	[	[	X
dpc-2653	134	2	22	22	NUM
dpc-2653	134	3	]	]	PUNCT
dpc-2653	134	4	.	.	PUNCT
dpc-2653	135	1	docetaxel	docetaxel	PROPN
dpc-2653	135	2	appears	appear	VERB
dpc-2653	135	3	to	to	PART
dpc-2653	135	4	have	have	AUX
dpc-2653	135	5	recently	recently	ADV
dpc-2653	135	6	become	become	VERB
dpc-2653	135	7	most	most	ADV
dpc-2653	135	8	specifically	specifically	ADV
dpc-2653	135	9	associated	associate	VERB
dpc-2653	135	10	with	with	ADP
dpc-2653	135	11	nail	nail	NOUN
dpc-2653	135	12	toxicity	toxicity	NOUN
dpc-2653	135	13	,	,	PUNCT
dpc-2653	135	14	occurring	occur	VERB
dpc-2653	135	15	in	in	ADP
dpc-2653	135	16	up	up	ADP
dpc-2653	135	17	to	to	PART
dpc-2653	135	18	30	30	NUM
dpc-2653	135	19	–	–	SYM
dpc-2653	135	20	40	40	NUM
dpc-2653	135	21	%	%	NOUN
dpc-2653	135	22	of	of	ADP
dpc-2653	135	23	patients	patient	NOUN
dpc-2653	135	24	[	[	X
dpc-2653	135	25	6	6	NUM
dpc-2653	135	26	,	,	PUNCT
dpc-2653	135	27	23	23	NUM
dpc-2653	135	28	]	]	PUNCT
dpc-2653	135	29	.	.	PUNCT
dpc-2653	136	1	nail	nail	NOUN
dpc-2653	136	2	changes	change	NOUN
dpc-2653	136	3	with	with	ADP
dpc-2653	136	4	taxanes	taxane	NOUN
dpc-2653	136	5	are	be	AUX
dpc-2653	136	6	very	very	ADV
dpc-2653	136	7	common	common	ADJ
dpc-2653	136	8	with	with	ADP
dpc-2653	136	9	some	some	DET
dpc-2653	136	10	series	series	NOUN
dpc-2653	136	11	reporting	report	VERB
dpc-2653	136	12	rates	rate	NOUN
dpc-2653	136	13	as	as	ADV
dpc-2653	136	14	high	high	ADJ
dpc-2653	136	15	as	as	ADP
dpc-2653	136	16	89	89	NUM
dpc-2653	136	17	%	%	NOUN
dpc-2653	136	18	after	after	ADP
dpc-2653	136	19	three	three	NUM
dpc-2653	136	20	treatment	treatment	NOUN
dpc-2653	136	21	cycles	cycle	NOUN
dpc-2653	136	22	[	[	X
dpc-2653	136	23	2429	2429	NUM
dpc-2653	136	24	]	]	PUNCT
dpc-2653	136	25	.	.	PUNCT
dpc-2653	137	1	these	these	DET
dpc-2653	137	2	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	137	3	agents	agent	NOUN
dpc-2653	137	4	may	may	AUX
dpc-2653	137	5	cause	cause	VERB
dpc-2653	137	6	diffuse	diffuse	ADJ
dpc-2653	137	7	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	137	8	,	,	PUNCT
dpc-2653	137	9	beau	beau	PROPN
dpc-2653	137	10	’s	’s	PART
dpc-2653	137	11	lines	line	NOUN
dpc-2653	137	12	,	,	PUNCT
dpc-2653	137	13	onychomadesis	onychomadesis	PROPN
dpc-2653	137	14	,	,	PUNCT
dpc-2653	137	15	mees	mee	NOUN
dpc-2653	137	16	’	'	PUNCT
dpc-2653	137	17	lines	line	NOUN
dpc-2653	137	18	,	,	PUNCT
dpc-2653	137	19	paronychia	paronychia	PROPN
dpc-2653	137	20	,	,	PUNCT
dpc-2653	137	21	subungual	subungual	ADJ
dpc-2653	137	22	hyperkeratosis	hyperkeratosis	NOUN
dpc-2653	137	23	,	,	PUNCT
dpc-2653	137	24	pyogenic	pyogenic	ADJ
dpc-2653	137	25	granuloma	granuloma	NOUN
dpc-2653	137	26	,	,	PUNCT
dpc-2653	137	27	subungual	subungual	ADJ
dpc-2653	137	28	&	&	CCONJ
dpc-2653	137	29	splinter	splinter	VERB
dpc-2653	137	30	hemorrhage	hemorrhage	NOUN
dpc-2653	137	31	,	,	PUNCT
dpc-2653	137	32	onycholysis/	onycholysis/	NUM
dpc-2653	137	33	exudative	exudative	ADJ
dpc-2653	137	34	onycholysis	onycholysis	NOUN
dpc-2653	137	35	,	,	PUNCT
dpc-2653	137	36	brittle	brittle	ADJ
dpc-2653	137	37	nails	nail	NOUN
dpc-2653	137	38	,	,	PUNCT
dpc-2653	137	39	onychorrhexis	onychorrhexis	ADJ
dpc-2653	137	40	or	or	CCONJ
dpc-2653	137	41	koilonychia	koilonychia	VERB
dpc-2653	137	42	(	(	PUNCT
dpc-2653	137	43	table	table	NOUN
dpc-2653	137	44	2	2	NUM
dpc-2653	137	45	)	)	PUNCT
dpc-2653	137	46	.	.	PUNCT
dpc-2653	138	1	nab	nab	PROPN
dpc-2653	138	2	-	-	PUNCT
dpc-2653	138	3	paclitaxel	paclitaxel	PROPN
dpc-2653	138	4	is	be	AUX
dpc-2653	138	5	a	a	DET
dpc-2653	138	6	novel	novel	NOUN
dpc-2653	138	7	,	,	PUNCT
dpc-2653	138	8	solvent	solvent	NOUN
dpc-2653	138	9	-	-	PUNCT
dpc-2653	138	10	free	free	ADJ
dpc-2653	138	11	,	,	PUNCT
dpc-2653	138	12	albumin	albumin	NOUN
dpc-2653	138	13	-	-	PUNCT
dpc-2653	138	14	bound	bind	VERB
dpc-2653	138	15	,	,	PUNCT
dpc-2653	138	16	colloidal	colloidal	NOUN
dpc-2653	138	17	suspension	suspension	NOUN
dpc-2653	138	18	(	(	PUNCT
dpc-2653	138	19	with	with	ADP
dpc-2653	138	20	a	a	DET
dpc-2653	138	21	size	size	NOUN
dpc-2653	138	22	of	of	ADP
dpc-2653	138	23	130	130	NUM
dpc-2653	138	24	nm	nm	NOUN
dpc-2653	138	25	)	)	PUNCT
dpc-2653	138	26	of	of	ADP
dpc-2653	138	27	paclitaxel	paclitaxel	PROPN
dpc-2653	138	28	that	that	PRON
dpc-2653	138	29	has	have	AUX
dpc-2653	138	30	led	lead	VERB
dpc-2653	138	31	to	to	ADP
dpc-2653	138	32	a	a	DET
dpc-2653	138	33	significant	significant	ADJ
dpc-2653	138	34	improvement	improvement	NOUN
dpc-2653	138	35	in	in	ADP
dpc-2653	138	36	progression	progression	NOUN
dpc-2653	138	37	-	-	PUNCT
dpc-2653	138	38	free	free	ADJ
dpc-2653	138	39	survival	survival	NOUN
dpc-2653	138	40	,	,	PUNCT
dpc-2653	138	41	median	median	ADJ
dpc-2653	138	42	overall	overall	ADJ
dpc-2653	138	43	survival	survival	NOUN
dpc-2653	138	44	,	,	PUNCT
dpc-2653	138	45	and	and	CCONJ
dpc-2653	138	46	overall	overall	ADJ
dpc-2653	138	47	response	response	NOUN
dpc-2653	138	48	rates	rate	NOUN
dpc-2653	138	49	in	in	ADP
dpc-2653	138	50	patients	patient	NOUN
dpc-2653	138	51	with	with	ADP
dpc-2653	138	52	metastatic	metastatic	ADJ
dpc-2653	138	53	breast	breast	NOUN
dpc-2653	138	54	and	and	CCONJ
dpc-2653	138	55	pancreatic	pancreatic	ADJ
dpc-2653	138	56	cancers	cancer	NOUN
dpc-2653	138	57	[	[	X
dpc-2653	138	58	21	21	NUM
dpc-2653	138	59	,	,	PUNCT
dpc-2653	138	60	30	30	NUM
dpc-2653	138	61	]	]	PUNCT
dpc-2653	138	62	.	.	PUNCT
dpc-2653	139	1	it	it	PRON
dpc-2653	139	2	has	have	AUX
dpc-2653	139	3	received	receive	VERB
dpc-2653	139	4	fda	fda	PROPN
dpc-2653	139	5	and	and	CCONJ
dpc-2653	139	6	ema	ema	PROPN
dpc-2653	139	7	approvals	approval	NOUN
dpc-2653	139	8	for	for	ADP
dpc-2653	139	9	the	the	DET
dpc-2653	139	10	treatment	treatment	NOUN
dpc-2653	139	11	of	of	ADP
dpc-2653	139	12	certain	certain	ADJ
dpc-2653	139	13	forms	form	NOUN
dpc-2653	139	14	of	of	ADP
dpc-2653	139	15	both	both	DET
dpc-2653	139	16	cancers	cancer	NOUN
dpc-2653	139	17	[	[	X
dpc-2653	139	18	30	30	NUM
dpc-2653	139	19	]	]	PUNCT
dpc-2653	139	20	.	.	PUNCT
dpc-2653	140	1	it	it	PRON
dpc-2653	140	2	is	be	AUX
dpc-2653	140	3	also	also	ADV
dpc-2653	140	4	approved	approve	VERB
dpc-2653	140	5	in	in	ADP
dpc-2653	140	6	the	the	DET
dpc-2653	140	7	us	us	PROPN
dpc-2653	140	8	for	for	ADP
dpc-2653	140	9	metastatic	metastatic	ADJ
dpc-2653	140	10	non	non	ADJ
dpc-2653	140	11	-	-	ADJ
dpc-2653	140	12	small	small	ADJ
dpc-2653	140	13	cell	cell	NOUN
dpc-2653	140	14	lung	lung	NOUN
dpc-2653	140	15	cancer	cancer	NOUN
dpc-2653	140	16	and	and	CCONJ
dpc-2653	140	17	is	be	AUX
dpc-2653	140	18	still	still	ADV
dpc-2653	140	19	under	under	ADP
dpc-2653	140	20	evaluation	evaluation	NOUN
dpc-2653	140	21	for	for	ADP
dpc-2653	140	22	several	several	ADJ
dpc-2653	140	23	other	other	ADJ
dpc-2653	140	24	indications	indication	NOUN
dpc-2653	140	25	,	,	PUNCT
dpc-2653	140	26	such	such	ADJ
dpc-2653	140	27	as	as	ADP
dpc-2653	140	28	metastatic	metastatic	ADJ
dpc-2653	140	29	urothelial	urothelial	ADJ
dpc-2653	140	30	tumors	tumor	NOUN
dpc-2653	141	1	[	[	X
dpc-2653	141	2	31	31	NUM
dpc-2653	141	3	,	,	PUNCT
dpc-2653	141	4	32	32	NUM
dpc-2653	141	5	]	]	PUNCT
dpc-2653	141	6	.	.	PUNCT
dpc-2653	142	1	nab	nab	PROPN
dpc-2653	142	2	-	-	PUNCT
dpc-2653	142	3	paclitaxel	paclitaxel	PROPN
dpc-2653	142	4	was	be	AUX
dpc-2653	142	5	developed	develop	VERB
dpc-2653	142	6	to	to	PART
dpc-2653	142	7	circumvent	circumvent	VERB
dpc-2653	142	8	the	the	DET
dpc-2653	142	9	highly	highly	ADV
dpc-2653	142	10	hydrophobic	hydrophobic	ADJ
dpc-2653	142	11	properties	property	NOUN
dpc-2653	142	12	of	of	ADP
dpc-2653	142	13	taxanes	taxane	NOUN
dpc-2653	142	14	and	and	CCONJ
dpc-2653	142	15	to	to	PART
dpc-2653	142	16	improve	improve	VERB
dpc-2653	142	17	intratumoral	intratumoral	ADJ
dpc-2653	142	18	paclitaxel	paclitaxel	ADJ
dpc-2653	142	19	penetration	penetration	NOUN
dpc-2653	142	20	[	[	X
dpc-2653	142	21	30	30	NUM
dpc-2653	142	22	,	,	PUNCT
dpc-2653	142	23	33	33	NUM
dpc-2653	142	24	]	]	PUNCT
dpc-2653	142	25	.	.	PUNCT
dpc-2653	143	1	since	since	SCONJ
dpc-2653	143	2	it	it	PRON
dpc-2653	143	3	is	be	AUX
dpc-2653	143	4	devoid	devoid	ADJ
dpc-2653	143	5	of	of	ADP
dpc-2653	143	6	cremophor	cremophor	NOUN
dpc-2653	143	7	el	el	PROPN
dpc-2653	143	8	®	®	PROPN
dpc-2653	143	9	(	(	PUNCT
dpc-2653	143	10	the	the	DET
dpc-2653	143	11	solvent	solvent	NOUN
dpc-2653	143	12	for	for	ADP
dpc-2653	143	13	paclitaxel	paclitaxel	PROPN
dpc-2653	143	14	)	)	PUNCT
dpc-2653	143	15	,	,	PUNCT
dpc-2653	143	16	several	several	ADJ
dpc-2653	143	17	significant	significant	ADJ
dpc-2653	143	18	adverse	adverse	ADJ
dpc-2653	143	19	events	event	NOUN
dpc-2653	143	20	such	such	ADJ
dpc-2653	143	21	as	as	ADP
dpc-2653	143	22	hypersensitivity	hypersensitivity	NOUN
dpc-2653	143	23	reactions	reaction	NOUN
dpc-2653	143	24	are	be	AUX
dpc-2653	143	25	less	less	ADV
dpc-2653	143	26	likely	likely	ADJ
dpc-2653	143	27	to	to	PART
dpc-2653	143	28	develop	develop	VERB
dpc-2653	143	29	[	[	X
dpc-2653	143	30	30	30	NUM
dpc-2653	143	31	]	]	PUNCT
dpc-2653	143	32	.	.	PUNCT
dpc-2653	144	1	nail	nail	NOUN
dpc-2653	144	2	toxicity	toxicity	NOUN
dpc-2653	144	3	has	have	AUX
dpc-2653	144	4	only	only	ADV
dpc-2653	144	5	been	be	AUX
dpc-2653	144	6	sporadically	sporadically	ADV
dpc-2653	144	7	reported	report	VERB
dpc-2653	144	8	with	with	ADP
dpc-2653	144	9	nab	nab	NOUN
dpc-2653	144	10	-	-	PUNCT
dpc-2653	144	11	paclitaxel	paclitaxel	ADJ
dpc-2653	144	12	,	,	PUNCT
dpc-2653	144	13	especially	especially	ADV
dpc-2653	144	14	onycholysis	onycholysis	NOUN
dpc-2653	144	15	,	,	PUNCT
dpc-2653	144	16	and	and	CCONJ
dpc-2653	144	17	is	be	AUX
dpc-2653	144	18	easily	easily	ADV
dpc-2653	144	19	manageable	manageable	ADJ
dpc-2653	145	1	[	[	X
dpc-2653	145	2	34	34	NUM
dpc-2653	145	3	]	]	PUNCT
dpc-2653	145	4	.	.	PUNCT
dpc-2653	146	1	the	the	DET
dpc-2653	146	2	overall	overall	ADJ
dpc-2653	146	3	incidence	incidence	NOUN
dpc-2653	146	4	of	of	ADP
dpc-2653	146	5	all	all	DET
dpc-2653	146	6	-	-	PUNCT
dpc-2653	146	7	grade	grade	NOUN
dpc-2653	146	8	nail	nail	NOUN
dpc-2653	146	9	toxic	toxic	ADJ
dpc-2653	146	10	effects	effect	NOUN
dpc-2653	146	11	with	with	ADP
dpc-2653	146	12	nab	nab	NOUN
dpc-2653	146	13	-	-	PUNCT
dpc-2653	146	14	paclitaxel	paclitaxel	PROPN
dpc-2653	146	15	is	be	AUX
dpc-2653	146	16	significantly	significantly	ADV
dpc-2653	146	17	lower	low	ADJ
dpc-2653	146	18	in	in	ADP
dpc-2653	146	19	comparison	comparison	NOUN
dpc-2653	146	20	with	with	ADP
dpc-2653	146	21	paclitaxel	paclitaxel	PROPN
dpc-2653	146	22	or	or	CCONJ
dpc-2653	146	23	docetaxel	docetaxel	PROPN
dpc-2653	146	24	(	(	PUNCT
dpc-2653	146	25	19.4	19.4	NUM
dpc-2653	146	26	%	%	NOUN
dpc-2653	146	27	)	)	PUNCT
dpc-2653	146	28	(	(	PUNCT
dpc-2653	146	29	95	95	NUM
dpc-2653	146	30	%	%	NOUN
dpc-2653	146	31	ci	ci	NOUN
dpc-2653	146	32	:	:	PUNCT
dpc-2653	146	33	11.8	11.8	NUM
dpc-2653	146	34	-	-	SYM
dpc-2653	146	35	30.3	30.3	NUM
dpc-2653	146	36	%	%	NOUN
dpc-2653	146	37	)	)	PUNCT
dpc-2653	147	1	[	[	X
dpc-2653	147	2	35	35	NUM
dpc-2653	147	3	]	]	SYM
dpc-2653	147	4	.	.	PUNCT
dpc-2653	148	1	vinca	vinca	NOUN
dpc-2653	148	2	alkaloids	alkaloid	NOUN
dpc-2653	148	3	:	:	PUNCT
dpc-2653	148	4	vincristine	vincristine	NOUN
dpc-2653	148	5	vinca	vinca	NOUN
dpc-2653	148	6	alkaloids	alkaloid	NOUN
dpc-2653	148	7	were	be	AUX
dpc-2653	148	8	historically	historically	ADV
dpc-2653	148	9	extracted	extract	VERB
dpc-2653	148	10	from	from	ADP
dpc-2653	148	11	the	the	DET
dpc-2653	148	12	leaves	leave	NOUN
dpc-2653	148	13	of	of	ADP
dpc-2653	148	14	the	the	DET
dpc-2653	148	15	madagascar	madagascar	ADJ
dpc-2653	148	16	periwinkle	periwinkle	NOUN
dpc-2653	148	17	(	(	PUNCT
dpc-2653	148	18	catharanthus	catharanthus	NOUN
dpc-2653	148	19	roseus	roseus	NOUN
dpc-2653	148	20	)	)	PUNCT
dpc-2653	148	21	.	.	PUNCT
dpc-2653	149	1	vincristine	vincristine	PROPN
dpc-2653	149	2	has	have	AUX
dpc-2653	149	3	been	be	AUX
dpc-2653	149	4	approved	approve	VERB
dpc-2653	149	5	for	for	ADP
dpc-2653	149	6	intravenous	intravenous	ADJ
dpc-2653	149	7	use	use	NOUN
dpc-2653	149	8	in	in	ADP
dpc-2653	149	9	the	the	DET
dpc-2653	149	10	united	united	PROPN
dpc-2653	149	11	states	states	PROPN
dpc-2653	149	12	and	and	CCONJ
dpc-2653	149	13	is	be	AUX
dpc-2653	149	14	often	often	ADV
dpc-2653	149	15	used	use	VERB
dpc-2653	149	16	in	in	ADP
dpc-2653	149	17	combination	combination	NOUN
dpc-2653	149	18	chemotherapy	chemotherapy	NOUN
dpc-2653	149	19	regimens	regimen	NOUN
dpc-2653	149	20	because	because	SCONJ
dpc-2653	149	21	of	of	ADP
dpc-2653	149	22	its	its	PRON
dpc-2653	149	23	lack	lack	NOUN
dpc-2653	149	24	of	of	ADP
dpc-2653	149	25	myelosuppression	myelosuppression	NOUN
dpc-2653	149	26	.	.	PUNCT
dpc-2653	150	1	vincristine	vincristine	NOUN
dpc-2653	150	2	is	be	AUX
dpc-2653	150	3	commonly	commonly	ADV
dpc-2653	150	4	used	use	VERB
dpc-2653	150	5	to	to	PART
dpc-2653	150	6	treat	treat	VERB
dpc-2653	150	7	acute	acute	ADJ
dpc-2653	150	8	lymphocytic	lymphocytic	ADJ
dpc-2653	150	9	leukemia	leukemia	NOUN
dpc-2653	150	10	,	,	PUNCT
dpc-2653	150	11	multiple	multiple	ADJ
dpc-2653	150	12	myeloma	myeloma	NOUN
dpc-2653	150	13	,	,	PUNCT
dpc-2653	150	14	chronic	chronic	ADJ
dpc-2653	150	15	lymphocytic	lymphocytic	ADJ
dpc-2653	150	16	leukemia	leukemia	NOUN
dpc-2653	150	17	,	,	PUNCT
dpc-2653	150	18	lymphoblastic	lymphoblastic	ADJ
dpc-2653	150	19	crisis	crisis	NOUN
dpc-2653	150	20	of	of	ADP
dpc-2653	150	21	chronic	chronic	ADJ
dpc-2653	150	22	myelogenous	myelogenous	ADJ
dpc-2653	150	23	anemia	anemia	NOUN
dpc-2653	150	24	,	,	PUNCT
dpc-2653	150	25	sarcomas	sarcoma	NOUN
dpc-2653	150	26	,	,	PUNCT
dpc-2653	150	27	and	and	CCONJ
dpc-2653	150	28	small	small	ADJ
dpc-2653	150	29	cell	cell	NOUN
dpc-2653	150	30	lung	lung	NOUN
dpc-2653	150	31	cancer	cancer	NOUN
dpc-2653	150	32	with	with	ADP
dpc-2653	150	33	distant	distant	ADJ
dpc-2653	150	34	metastases	metastasis	NOUN
dpc-2653	150	35	[	[	X
dpc-2653	150	36	12	12	NUM
dpc-2653	150	37	]	]	PUNCT
dpc-2653	150	38	.	.	PUNCT
dpc-2653	151	1	vincristine	vincristine	PROPN
dpc-2653	151	2	may	may	AUX
dpc-2653	151	3	cause	cause	VERB
dpc-2653	151	4	diffuse	diffuse	ADJ
dpc-2653	151	5	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	151	6	,	,	PUNCT
dpc-2653	151	7	longitudinal	longitudinal	ADJ
dpc-2653	151	8	melanonychia	melanonychia	NOUN
dpc-2653	151	9	,	,	PUNCT
dpc-2653	151	10	beau	beau	PROPN
dpc-2653	151	11	’s	’s	PART
dpc-2653	151	12	lines	line	NOUN
dpc-2653	151	13	,	,	PUNCT
dpc-2653	151	14	onychomadesis	onychomadesis	PROPN
dpc-2653	151	15	,	,	PUNCT
dpc-2653	151	16	mees	mee	NOUN
dpc-2653	151	17	’	'	PUNCT
dpc-2653	151	18	lines	line	NOUN
dpc-2653	151	19	or	or	CCONJ
dpc-2653	151	20	muehrcke	muehrcke	NOUN
dpc-2653	151	21	’s	’s	PART
dpc-2653	151	22	lines	line	NOUN
dpc-2653	151	23	(	(	PUNCT
dpc-2653	151	24	table	table	NOUN
dpc-2653	151	25	2	2	NUM
dpc-2653	151	26	)	)	PUNCT
dpc-2653	151	27	.	.	PUNCT
dpc-2653	152	1	topoisomerase	topoisomerase	ADJ
dpc-2653	152	2	inhibitors	inhibitor	NOUN
dpc-2653	152	3	topoisomerase	topoisomerase	PROPN
dpc-2653	152	4	ii	ii	NOUN
dpc-2653	152	5	:	:	PUNCT
dpc-2653	152	6	etoposide	etoposide	PROPN
dpc-2653	152	7	etoposide	etoposide	NOUN
dpc-2653	152	8	is	be	AUX
dpc-2653	152	9	an	an	DET
dpc-2653	152	10	inhibitor	inhibitor	NOUN
dpc-2653	152	11	of	of	ADP
dpc-2653	152	12	the	the	DET
dpc-2653	152	13	enzyme	enzyme	NOUN
dpc-2653	152	14	topoisomerase	topoisomerase	NOUN
dpc-2653	152	15	ii	ii	NOUN
dpc-2653	152	16	,	,	PUNCT
dpc-2653	152	17	which	which	PRON
dpc-2653	152	18	relieves	relieve	VERB
dpc-2653	152	19	the	the	DET
dpc-2653	152	20	helical	helical	ADJ
dpc-2653	152	21	strain	strain	NOUN
dpc-2653	152	22	during	during	ADP
dpc-2653	152	23	dna	dna	NOUN
dpc-2653	152	24	replication	replication	NOUN
dpc-2653	152	25	by	by	ADP
dpc-2653	152	26	cutting	cut	VERB
dpc-2653	152	27	both	both	DET
dpc-2653	152	28	strands	strand	NOUN
dpc-2653	152	29	of	of	ADP
dpc-2653	152	30	dna	dna	NOUN
dpc-2653	152	31	simultaneously	simultaneously	ADV
dpc-2653	152	32	.	.	PUNCT
dpc-2653	153	1	topoisomerase	topoisomerase	ADJ
dpc-2653	153	2	review	review	NOUN
dpc-2653	153	3	|	|	ADV
dpc-2653	153	4	dermatol	dermatol	ADJ
dpc-2653	153	5	pract	pract	NOUN
dpc-2653	153	6	concept	concept	NOUN
dpc-2653	153	7	.	.	PUNCT
dpc-2653	154	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	154	2	7	7	NUM
dpc-2653	154	3	bruton	bruton	PROPN
dpc-2653	154	4	’s	’s	PART
dpc-2653	154	5	tyrosine	tyrosine	PROPN
dpc-2653	154	6	kinase	kinase	PROPN
dpc-2653	154	7	(	(	PUNCT
dpc-2653	154	8	btk	btk	PROPN
dpc-2653	154	9	)	)	PUNCT
dpc-2653	154	10	inhibitors	inhibitor	NOUN
dpc-2653	154	11	bruton	bruton	PROPN
dpc-2653	154	12	’s	’s	PART
dpc-2653	154	13	tyrosine	tyrosine	PROPN
dpc-2653	154	14	kinase	kinase	PROPN
dpc-2653	154	15	inhibitor	inhibitor	PROPN
dpc-2653	154	16	,	,	PUNCT
dpc-2653	154	17	ibrutinib	ibrutinib	PROPN
dpc-2653	154	18	,	,	PUNCT
dpc-2653	154	19	is	be	AUX
dpc-2653	154	20	a	a	DET
dpc-2653	154	21	small	small	ADJ
dpc-2653	154	22	molecule	molecule	NOUN
dpc-2653	154	23	that	that	PRON
dpc-2653	154	24	binds	bind	VERB
dpc-2653	154	25	to	to	ADP
dpc-2653	154	26	a	a	DET
dpc-2653	154	27	protein	protein	NOUN
dpc-2653	154	28	,	,	PUNCT
dpc-2653	154	29	important	important	ADJ
dpc-2653	154	30	in	in	ADP
dpc-2653	154	31	b	b	NOUN
dpc-2653	154	32	-	-	PUNCT
dpc-2653	154	33	cells	cell	NOUN
dpc-2653	154	34	.	.	PUNCT
dpc-2653	155	1	it	it	PRON
dpc-2653	155	2	is	be	AUX
dpc-2653	155	3	used	use	VERB
dpc-2653	155	4	for	for	ADP
dpc-2653	155	5	the	the	DET
dpc-2653	155	6	treatment	treatment	NOUN
dpc-2653	155	7	of	of	ADP
dpc-2653	155	8	chronic	chronic	ADJ
dpc-2653	155	9	lymphocytic	lymphocytic	ADJ
dpc-2653	155	10	leukemia	leukemia	NOUN
dpc-2653	155	11	,	,	PUNCT
dpc-2653	155	12	waldenström	waldenström	NOUN
dpc-2653	155	13	’s	’s	NOUN
dpc-2653	155	14	macroglobulinemia	macroglobulinemia	ADJ
dpc-2653	155	15	,	,	PUNCT
dpc-2653	155	16	refractory	refractory	NOUN
dpc-2653	155	17	and	and	CCONJ
dpc-2653	155	18	relapsed	relapse	VERB
dpc-2653	155	19	mantle	mantle	ADJ
dpc-2653	155	20	-	-	PUNCT
dpc-2653	155	21	cell	cell	NOUN
dpc-2653	155	22	lymphoma	lymphoma	NOUN
dpc-2653	155	23	.	.	PUNCT
dpc-2653	156	1	brittle	brittle	ADJ
dpc-2653	156	2	nails	nail	NOUN
dpc-2653	156	3	are	be	AUX
dpc-2653	156	4	the	the	DET
dpc-2653	156	5	most	most	ADV
dpc-2653	156	6	common	common	ADJ
dpc-2653	156	7	nail	nail	NOUN
dpc-2653	156	8	change	change	NOUN
dpc-2653	156	9	,	,	PUNCT
dpc-2653	156	10	seen	see	VERB
dpc-2653	156	11	in	in	ADP
dpc-2653	156	12	about	about	ADP
dpc-2653	156	13	2/3	2/3	NUM
dpc-2653	156	14	of	of	ADP
dpc-2653	156	15	treated	treat	VERB
dpc-2653	156	16	patients	patient	NOUN
dpc-2653	156	17	,	,	PUNCT
dpc-2653	156	18	followed	follow	VERB
dpc-2653	156	19	by	by	ADP
dpc-2653	156	20	onychoschizia	onychoschizia	PROPN
dpc-2653	156	21	,	,	PUNCT
dpc-2653	156	22	onychorrhexis	onychorrhexis	ADJ
dpc-2653	156	23	and	and	CCONJ
dpc-2653	156	24	mild	mild	ADJ
dpc-2653	156	25	onycholysis	onycholysis	NOUN
dpc-2653	156	26	[	[	X
dpc-2653	156	27	38	38	NUM
dpc-2653	156	28	]	]	PUNCT
dpc-2653	156	29	(	(	PUNCT
dpc-2653	156	30	table	table	NOUN
dpc-2653	156	31	3	3	NUM
dpc-2653	156	32	)	)	PUNCT
dpc-2653	156	33	.	.	PUNCT
dpc-2653	157	1	anti	anti	ADJ
dpc-2653	157	2	-	-	ADJ
dpc-2653	157	3	her2	her2	ADJ
dpc-2653	157	4	/	/	SYM
dpc-2653	157	5	anti	anti	ADJ
dpc-2653	157	6	-	-	ADJ
dpc-2653	157	7	her	her	PRON
dpc-2653	157	8	anti	anti	ADJ
dpc-2653	157	9	-	-	ADJ
dpc-2653	157	10	human	human	ADJ
dpc-2653	157	11	epidermal	epidermal	ADJ
dpc-2653	157	12	growth	growth	NOUN
dpc-2653	157	13	factor	factor	NOUN
dpc-2653	157	14	receptor	receptor	NOUN
dpc-2653	157	15	2	2	NUM
dpc-2653	157	16	(	(	PUNCT
dpc-2653	157	17	anti	anti	ADJ
dpc-2653	157	18	-	-	ADJ
dpc-2653	157	19	her2	her2	PRON
dpc-2653	157	20	)	)	PUNCT
dpc-2653	157	21	is	be	AUX
dpc-2653	157	22	a	a	DET
dpc-2653	157	23	class	class	NOUN
dpc-2653	157	24	of	of	ADP
dpc-2653	157	25	medicines	medicine	NOUN
dpc-2653	157	26	used	use	VERB
dpc-2653	157	27	to	to	PART
dpc-2653	157	28	treat	treat	VERB
dpc-2653	157	29	all	all	DET
dpc-2653	157	30	stages	stage	NOUN
dpc-2653	157	31	of	of	ADP
dpc-2653	157	32	her2	her2	NOUN
dpc-2653	157	33	-	-	PUNCT
dpc-2653	157	34	positive	positive	ADJ
dpc-2653	157	35	breast	breast	NOUN
dpc-2653	157	36	cancer	cancer	NOUN
dpc-2653	157	37	,	,	PUNCT
dpc-2653	157	38	from	from	ADP
dpc-2653	157	39	early	early	ADJ
dpc-2653	157	40	-	-	PUNCT
dpc-2653	157	41	stage	stage	NOUN
dpc-2653	157	42	to	to	ADP
dpc-2653	157	43	metastatic	metastatic	ADJ
dpc-2653	157	44	disease	disease	NOUN
dpc-2653	157	45	.	.	PUNCT
dpc-2653	158	1	trastuzumab	trastuzumab	NOUN
dpc-2653	158	2	was	be	AUX
dpc-2653	158	3	shown	show	VERB
dpc-2653	158	4	to	to	PART
dpc-2653	158	5	cause	cause	VERB
dpc-2653	158	6	thin	thin	ADJ
dpc-2653	158	7	nails	nail	NOUN
dpc-2653	158	8	[	[	X
dpc-2653	158	9	37	37	NUM
dpc-2653	158	10	,	,	PUNCT
dpc-2653	158	11	38	38	NUM
dpc-2653	158	12	]	]	PUNCT
dpc-2653	158	13	.	.	PUNCT
dpc-2653	159	1	lapatinib	lapatinib	PROPN
dpc-2653	159	2	(	(	PUNCT
dpc-2653	159	3	breast	breast	NOUN
dpc-2653	159	4	cancer	cancer	NOUN
dpc-2653	159	5	and	and	CCONJ
dpc-2653	159	6	solid	solid	ADJ
dpc-2653	159	7	tumors	tumor	NOUN
dpc-2653	159	8	)	)	PUNCT
dpc-2653	159	9	,	,	PUNCT
dpc-2653	159	10	afatinib	afatinib	NOUN
dpc-2653	159	11	(	(	PUNCT
dpc-2653	159	12	nsclc	nsclc	NOUN
dpc-2653	159	13	)	)	PUNCT
dpc-2653	159	14	and	and	CCONJ
dpc-2653	159	15	dacomitinib	dacomitinib	PROPN
dpc-2653	159	16	(	(	PUNCT
dpc-2653	159	17	nsclc	nsclc	NOUN
dpc-2653	159	18	)	)	PUNCT
dpc-2653	159	19	,	,	PUNCT
dpc-2653	159	20	besides	besides	SCONJ
dpc-2653	159	21	thin	thin	ADJ
dpc-2653	159	22	nails	nail	NOUN
dpc-2653	159	23	,	,	PUNCT
dpc-2653	159	24	may	may	AUX
dpc-2653	159	25	induce	induce	VERB
dpc-2653	159	26	nail	nail	NOUN
dpc-2653	159	27	reactions	reaction	NOUN
dpc-2653	159	28	such	such	ADJ
dpc-2653	159	29	as	as	ADP
dpc-2653	159	30	paronychia	paronychia	PROPN
dpc-2653	159	31	,	,	PUNCT
dpc-2653	159	32	pyogenic	pyogenic	ADJ
dpc-2653	159	33	granuloma	granuloma	NOUN
dpc-2653	159	34	,	,	PUNCT
dpc-2653	159	35	slower	slow	ADJ
dpc-2653	159	36	growth	growth	NOUN
dpc-2653	159	37	rate	rate	NOUN
dpc-2653	159	38	and	and	CCONJ
dpc-2653	159	39	mild	mild	ADJ
dpc-2653	159	40	onycholysis	onycholysis	NOUN
dpc-2653	159	41	[	[	X
dpc-2653	159	42	37	37	NUM
dpc-2653	159	43	,	,	PUNCT
dpc-2653	159	44	38	38	NUM
dpc-2653	159	45	]	]	PUNCT
dpc-2653	159	46	(	(	PUNCT
dpc-2653	159	47	table	table	NOUN
dpc-2653	159	48	3	3	NUM
dpc-2653	159	49	)	)	PUNCT
dpc-2653	159	50	.	.	PUNCT
dpc-2653	160	1	anti	anti	PROPN
dpc-2653	160	2	-	-	PROPN
dpc-2653	160	3	mek	mek	PROPN
dpc-2653	160	4	mitogen	mitogen	NOUN
dpc-2653	160	5	-	-	PUNCT
dpc-2653	160	6	activated	activate	VERB
dpc-2653	160	7	protein	protein	NOUN
dpc-2653	160	8	kinase	kinase	NOUN
dpc-2653	160	9	enzymes	enzyme	NOUN
dpc-2653	160	10	mek1	mek1	PROPN
dpc-2653	160	11	and/	and/	PROPN
dpc-2653	160	12	or	or	CCONJ
dpc-2653	160	13	mek2	mek2	PROPN
dpc-2653	160	14	,	,	PUNCT
dpc-2653	160	15	trametinib	trametinib	NOUN
dpc-2653	160	16	(	(	PUNCT
dpc-2653	160	17	metastatic	metastatic	ADJ
dpc-2653	160	18	melanoma	melanoma	NOUN
dpc-2653	160	19	)	)	PUNCT
dpc-2653	160	20	,	,	PUNCT
dpc-2653	160	21	cobimetinib	cobimetinib	NOUN
dpc-2653	160	22	(	(	PUNCT
dpc-2653	160	23	melanoma	melanoma	NOUN
dpc-2653	160	24	)	)	PUNCT
dpc-2653	160	25	and	and	CCONJ
dpc-2653	160	26	selumetinib	selumetinib	PROPN
dpc-2653	160	27	(	(	PUNCT
dpc-2653	160	28	neurofibromatosis	neurofibromatosis	NOUN
dpc-2653	160	29	type	type	NOUN
dpc-2653	160	30	i	i	PRON
dpc-2653	160	31	with	with	ADP
dpc-2653	160	32	antibacterial	antibacterial	ADJ
dpc-2653	160	33	soaks	soak	NOUN
dpc-2653	160	34	(	(	PUNCT
dpc-2653	160	35	chlorhexidine	chlorhexidine	NOUN
dpc-2653	160	36	or	or	CCONJ
dpc-2653	160	37	vinegar	vinegar	NOUN
dpc-2653	160	38	in	in	ADP
dpc-2653	160	39	water	water	NOUN
dpc-2653	160	40	)	)	PUNCT
dpc-2653	161	1	[	[	X
dpc-2653	161	2	38	38	NUM
dpc-2653	161	3	]	]	PUNCT
dpc-2653	161	4	.	.	PUNCT
dpc-2653	161	5	warm	warm	ADJ
dpc-2653	161	6	compresses	compress	NOUN
dpc-2653	161	7	,	,	PUNCT
dpc-2653	161	8	silver	silver	NOUN
dpc-2653	161	9	nitrate	nitrate	NOUN
dpc-2653	161	10	,	,	PUNCT
dpc-2653	161	11	topical	topical	ADJ
dpc-2653	161	12	corticosteroids	corticosteroid	NOUN
dpc-2653	161	13	and	and	CCONJ
dpc-2653	161	14	systemic	systemic	ADJ
dpc-2653	161	15	tetracyclines	tetracycline	NOUN
dpc-2653	161	16	are	be	AUX
dpc-2653	161	17	recommended	recommend	VERB
dpc-2653	161	18	in	in	ADP
dpc-2653	161	19	order	order	NOUN
dpc-2653	161	20	to	to	PART
dpc-2653	161	21	reduce	reduce	VERB
dpc-2653	161	22	periungual	periungual	ADJ
dpc-2653	161	23	inflammation	inflammation	NOUN
dpc-2653	161	24	,	,	PUNCT
dpc-2653	161	25	depending	depend	VERB
dpc-2653	161	26	on	on	ADP
dpc-2653	161	27	the	the	DET
dpc-2653	161	28	grade	grade	NOUN
dpc-2653	161	29	of	of	ADP
dpc-2653	161	30	the	the	DET
dpc-2653	161	31	toxicity	toxicity	NOUN
dpc-2653	161	32	.	.	PUNCT
dpc-2653	162	1	angiogenesis	angiogenesis	NOUN
dpc-2653	162	2	-	-	PUNCT
dpc-2653	162	3	inducing	induce	VERB
dpc-2653	162	4	inhibitors	inhibitor	NOUN
dpc-2653	162	5	sorafenib	sorafenib	NOUN
dpc-2653	162	6	and	and	CCONJ
dpc-2653	162	7	sunitinib	sunitinib	NOUN
dpc-2653	162	8	are	be	AUX
dpc-2653	162	9	multikinase	multikinase	VERB
dpc-2653	162	10	inhibitors	inhibitor	NOUN
dpc-2653	162	11	that	that	PRON
dpc-2653	162	12	specifically	specifically	ADV
dpc-2653	162	13	target	target	VERB
dpc-2653	162	14	tumor	tumor	NOUN
dpc-2653	162	15	cell	cell	NOUN
dpc-2653	162	16	angiogenesis	angiogenesis	NOUN
dpc-2653	162	17	and	and	CCONJ
dpc-2653	162	18	proliferation	proliferation	NOUN
dpc-2653	162	19	via	via	ADP
dpc-2653	162	20	vegfr	vegfr	NOUN
dpc-2653	162	21	(	(	PUNCT
dpc-2653	162	22	vascular	vascular	ADJ
dpc-2653	162	23	endothelial	endothelial	ADJ
dpc-2653	162	24	growth	growth	NOUN
dpc-2653	162	25	factor	factor	NOUN
dpc-2653	162	26	)	)	PUNCT
dpc-2653	162	27	,	,	PUNCT
dpc-2653	162	28	pdgrf	pdgrf	INTJ
dpc-2653	162	29	(	(	PUNCT
dpc-2653	162	30	platelet	platelet	NOUN
dpc-2653	162	31	-	-	PUNCT
dpc-2653	162	32	derived	derive	VERB
dpc-2653	162	33	growth	growth	NOUN
dpc-2653	162	34	factor	factor	NOUN
dpc-2653	162	35	receptor	receptor	NOUN
dpc-2653	162	36	)	)	PUNCT
dpc-2653	162	37	and	and	CCONJ
dpc-2653	162	38	other	other	ADJ
dpc-2653	162	39	kinases	kinase	NOUN
dpc-2653	163	1	[	[	X
dpc-2653	163	2	38	38	NUM
dpc-2653	163	3	]	]	PUNCT
dpc-2653	163	4	.	.	PUNCT
dpc-2653	164	1	sorafenib	sorafenib	PROPN
dpc-2653	164	2	is	be	AUX
dpc-2653	164	3	indicated	indicate	VERB
dpc-2653	164	4	in	in	ADP
dpc-2653	164	5	renal	renal	ADJ
dpc-2653	164	6	cell	cell	NOUN
dpc-2653	164	7	carcinoma	carcinoma	NOUN
dpc-2653	164	8	,	,	PUNCT
dpc-2653	164	9	nonsmall	nonsmall	NOUN
dpc-2653	164	10	cell	cell	NOUN
dpc-2653	164	11	lung	lung	NOUN
dpc-2653	164	12	cancer	cancer	NOUN
dpc-2653	164	13	,	,	PUNCT
dpc-2653	164	14	hepatocellular	hepatocellular	ADJ
dpc-2653	164	15	carcinoma	carcinoma	NOUN
dpc-2653	164	16	,	,	PUNCT
dpc-2653	164	17	melanoma	melanoma	NOUN
dpc-2653	164	18	,	,	PUNCT
dpc-2653	164	19	pancreatic	pancreatic	ADJ
dpc-2653	164	20	and	and	CCONJ
dpc-2653	164	21	colon	colon	NOUN
dpc-2653	164	22	cancers	cancer	NOUN
dpc-2653	164	23	,	,	PUNCT
dpc-2653	164	24	whilst	whilst	SCONJ
dpc-2653	164	25	sunitinib	sunitinib	NOUN
dpc-2653	164	26	is	be	AUX
dpc-2653	164	27	prescribed	prescribe	VERB
dpc-2653	164	28	for	for	ADP
dpc-2653	164	29	renal	renal	ADJ
dpc-2653	164	30	cell	cell	NOUN
dpc-2653	164	31	carcinoma	carcinoma	NOUN
dpc-2653	164	32	,	,	PUNCT
dpc-2653	164	33	breast	breast	NOUN
dpc-2653	164	34	cancer	cancer	NOUN
dpc-2653	164	35	,	,	PUNCT
dpc-2653	164	36	colon	colon	NOUN
dpc-2653	164	37	cancer	cancer	NOUN
dpc-2653	164	38	and	and	CCONJ
dpc-2653	164	39	gastrointestinal	gastrointestinal	ADJ
dpc-2653	164	40	stromal	stromal	ADJ
dpc-2653	164	41	tumor	tumor	NOUN
dpc-2653	164	42	.	.	PUNCT
dpc-2653	165	1	both	both	PRON
dpc-2653	165	2	are	be	AUX
dpc-2653	165	3	orally	orally	ADV
dpc-2653	165	4	administered	administer	VERB
dpc-2653	165	5	.	.	PUNCT
dpc-2653	166	1	studies	study	NOUN
dpc-2653	166	2	report	report	VERB
dpc-2653	166	3	that	that	SCONJ
dpc-2653	166	4	during	during	ADP
dpc-2653	166	5	the	the	DET
dpc-2653	166	6	first	first	ADJ
dpc-2653	166	7	2	2	NUM
dpc-2653	166	8	months	month	NOUN
dpc-2653	166	9	of	of	ADP
dpc-2653	166	10	therapy	therapy	NOUN
dpc-2653	166	11	,	,	PUNCT
dpc-2653	166	12	70	70	NUM
dpc-2653	166	13	%	%	NOUN
dpc-2653	166	14	and	and	CCONJ
dpc-2653	166	15	25	25	NUM
dpc-2653	166	16	%	%	NOUN
dpc-2653	166	17	of	of	ADP
dpc-2653	166	18	patients	patient	NOUN
dpc-2653	166	19	taking	take	VERB
dpc-2653	166	20	sorafenib	sorafenib	NOUN
dpc-2653	166	21	and	and	CCONJ
dpc-2653	166	22	sunitinib	sunitinib	NOUN
dpc-2653	166	23	,	,	PUNCT
dpc-2653	166	24	respectively	respectively	ADV
dpc-2653	166	25	,	,	PUNCT
dpc-2653	166	26	developed	develop	VERB
dpc-2653	166	27	fingernail	fingernail	NOUN
dpc-2653	166	28	subungual	subungual	ADJ
dpc-2653	166	29	splinter	splinter	VERB
dpc-2653	166	30	hemorrhages	hemorrhage	NOUN
dpc-2653	166	31	[	[	X
dpc-2653	166	32	41	41	NUM
dpc-2653	166	33	]	]	PUNCT
dpc-2653	166	34	(	(	PUNCT
dpc-2653	166	35	table	table	NOUN
dpc-2653	166	36	3	3	NUM
dpc-2653	166	37	)	)	PUNCT
dpc-2653	166	38	.	.	PUNCT
dpc-2653	167	1	the	the	DET
dpc-2653	167	2	latter	latter	ADJ
dpc-2653	167	3	resolved	resolve	VERB
dpc-2653	167	4	spontaneously	spontaneously	ADV
dpc-2653	167	5	without	without	ADP
dpc-2653	167	6	treatment	treatment	NOUN
dpc-2653	167	7	.	.	PUNCT
dpc-2653	168	1	this	this	PRON
dpc-2653	168	2	may	may	AUX
dpc-2653	168	3	be	be	AUX
dpc-2653	168	4	linked	link	VERB
dpc-2653	168	5	to	to	ADP
dpc-2653	168	6	the	the	DET
dpc-2653	168	7	role	role	NOUN
dpc-2653	168	8	vegfr	vegfr	NOUN
dpc-2653	168	9	play	play	NOUN
dpc-2653	168	10	in	in	ADP
dpc-2653	168	11	the	the	DET
dpc-2653	168	12	renewal	renewal	NOUN
dpc-2653	168	13	of	of	ADP
dpc-2653	168	14	capillaries	capillary	NOUN
dpc-2653	168	15	and	and	CCONJ
dpc-2653	168	16	their	their	PRON
dpc-2653	168	17	sustain	sustain	NOUN
dpc-2653	168	18	despite	despite	SCONJ
dpc-2653	168	19	frequent	frequent	ADJ
dpc-2653	168	20	injuries	injury	NOUN
dpc-2653	168	21	at	at	ADP
dpc-2653	168	22	the	the	DET
dpc-2653	168	23	distal	distal	ADJ
dpc-2653	168	24	fingers	finger	NOUN
dpc-2653	168	25	,	,	PUNCT
dpc-2653	168	26	which	which	PRON
dpc-2653	168	27	is	be	AUX
dpc-2653	168	28	now	now	ADV
dpc-2653	168	29	inhibited	inhibit	VERB
dpc-2653	168	30	due	due	ADP
dpc-2653	168	31	to	to	ADP
dpc-2653	168	32	sorafenib	sorafenib	NOUN
dpc-2653	168	33	and	and	CCONJ
dpc-2653	168	34	sunitinib	sunitinib	NOUN
dpc-2653	168	35	intake	intake	VERB
dpc-2653	169	1	[	[	X
dpc-2653	169	2	38	38	NUM
dpc-2653	169	3	,	,	PUNCT
dpc-2653	169	4	41	41	NUM
dpc-2653	169	5	]	]	PUNCT
dpc-2653	169	6	.	.	PUNCT
dpc-2653	170	1	figure	figure	NOUN
dpc-2653	170	2	2	2	NUM
dpc-2653	170	3	.	.	PUNCT
dpc-2653	171	1	nail	nail	NOUN
dpc-2653	171	2	toxicities	toxicity	NOUN
dpc-2653	171	3	due	due	ADJ
dpc-2653	171	4	to	to	ADP
dpc-2653	171	5	targeted	target	VERB
dpc-2653	171	6	biologic	biologic	NOUN
dpc-2653	171	7	drugs	drug	NOUN
dpc-2653	171	8	.	.	PUNCT
dpc-2653	172	1	a.	a.	NOUN
dpc-2653	172	2	paronychia	paronychia	PROPN
dpc-2653	172	3	due	due	ADP
dpc-2653	172	4	to	to	ADP
dpc-2653	172	5	treatment	treatment	NOUN
dpc-2653	172	6	with	with	ADP
dpc-2653	172	7	egfr	egfr	ADJ
dpc-2653	172	8	tyrosine	tyrosine	PROPN
dpc-2653	172	9	kinase	kinase	PROPN
dpc-2653	172	10	inhibitor	inhibitor	PROPN
dpc-2653	172	11	(	(	PUNCT
dpc-2653	172	12	panitumumab	panitumumab	NOUN
dpc-2653	172	13	)	)	PUNCT
dpc-2653	172	14	for	for	ADP
dpc-2653	172	15	colorectal	colorectal	ADJ
dpc-2653	172	16	cancer	cancer	NOUN
dpc-2653	172	17	:	:	PUNCT
dpc-2653	172	18	proximal	proximal	ADJ
dpc-2653	172	19	nail	nail	NOUN
dpc-2653	172	20	fold	fold	NOUN
dpc-2653	172	21	is	be	AUX
dpc-2653	172	22	painful	painful	ADJ
dpc-2653	172	23	,	,	PUNCT
dpc-2653	172	24	erythematous	erythematous	ADJ
dpc-2653	172	25	and	and	CCONJ
dpc-2653	172	26	swollen	swell	VERB
dpc-2653	172	27	with	with	ADP
dpc-2653	172	28	presence	presence	NOUN
dpc-2653	172	29	of	of	ADP
dpc-2653	172	30	oozing	oozing	ADJ
dpc-2653	172	31	and	and	CCONJ
dpc-2653	172	32	crusting	crusting	NOUN
dpc-2653	172	33	,	,	PUNCT
dpc-2653	172	34	b.	b.	PROPN
dpc-2653	172	35	same	same	ADJ
dpc-2653	172	36	patient	patient	NOUN
dpc-2653	172	37	as	as	ADP
dpc-2653	172	38	a.	a.	NOUN
dpc-2653	172	39	:	:	PUNCT
dpc-2653	172	40	close	close	VERB
dpc-2653	172	41	-	-	PUNCT
dpc-2653	172	42	up	up	NOUN
dpc-2653	172	43	to	to	ADP
dpc-2653	172	44	a	a	DET
dpc-2653	172	45	pyogenic	pyogenic	ADJ
dpc-2653	172	46	granuloma	granuloma	NOUN
dpc-2653	172	47	that	that	PRON
dpc-2653	172	48	frequently	frequently	ADV
dpc-2653	172	49	accompanies	accompany	VERB
dpc-2653	172	50	paronychia	paronychia	NOUN
dpc-2653	172	51	due	due	ADP
dpc-2653	172	52	to	to	ADP
dpc-2653	172	53	egfr	egfr	ADJ
dpc-2653	172	54	inhibitors	inhibitor	NOUN
dpc-2653	172	55	.	.	PUNCT
dpc-2653	173	1	c	c	NOUN
dpc-2653	173	2	and	and	CCONJ
dpc-2653	173	3	d.	d.	PROPN
dpc-2653	173	4	clinical	clinical	PROPN
dpc-2653	173	5	and	and	CCONJ
dpc-2653	173	6	dermoscopy	dermoscopy	VERB
dpc-2653	173	7	image	image	NOUN
dpc-2653	173	8	of	of	ADP
dpc-2653	173	9	brittle	brittle	ADJ
dpc-2653	173	10	nails	nail	NOUN
dpc-2653	173	11	during	during	ADP
dpc-2653	173	12	egfr	egfr	ADJ
dpc-2653	173	13	inhibitor	inhibitor	NOUN
dpc-2653	173	14	therapy	therapy	NOUN
dpc-2653	173	15	for	for	ADP
dpc-2653	173	16	lung	lung	NOUN
dpc-2653	173	17	cancer	cancer	NOUN
dpc-2653	173	18	.	.	PUNCT
dpc-2653	174	1	the	the	DET
dpc-2653	174	2	nail	nail	NOUN
dpc-2653	174	3	plate	plate	NOUN
dpc-2653	174	4	is	be	AUX
dpc-2653	174	5	fragile	fragile	ADJ
dpc-2653	174	6	and	and	CCONJ
dpc-2653	174	7	the	the	DET
dpc-2653	174	8	surface	surface	NOUN
dpc-2653	174	9	of	of	ADP
dpc-2653	174	10	the	the	DET
dpc-2653	174	11	nail	nail	NOUN
dpc-2653	174	12	presents	present	NOUN
dpc-2653	174	13	longitudinal	longitudinal	ADJ
dpc-2653	174	14	fine	fine	ADJ
dpc-2653	174	15	fissures	fissure	NOUN
dpc-2653	174	16	while	while	SCONJ
dpc-2653	174	17	the	the	DET
dpc-2653	174	18	distal	distal	ADJ
dpc-2653	174	19	edge	edge	NOUN
dpc-2653	174	20	of	of	ADP
dpc-2653	174	21	the	the	DET
dpc-2653	174	22	plate	plate	NOUN
dpc-2653	174	23	appears	appear	VERB
dpc-2653	174	24	to	to	PART
dpc-2653	174	25	crumble	crumble	VERB
dpc-2653	174	26	and	and	CCONJ
dpc-2653	174	27	is	be	AUX
dpc-2653	174	28	not	not	PART
dpc-2653	174	29	sharply	sharply	ADV
dpc-2653	174	30	delineated	delineate	VERB
dpc-2653	174	31	.	.	PUNCT
dpc-2653	175	1	in	in	ADP
dpc-2653	175	2	dermoscopy	dermoscopy	NOUN
dpc-2653	175	3	presence	presence	NOUN
dpc-2653	175	4	of	of	ADP
dpc-2653	175	5	splinter	splinter	NOUN
dpc-2653	175	6	hemorrhages	hemorrhage	NOUN
dpc-2653	175	7	can	can	AUX
dpc-2653	175	8	also	also	ADV
dpc-2653	175	9	be	be	AUX
dpc-2653	175	10	detected	detect	VERB
dpc-2653	175	11	.	.	PUNCT
dpc-2653	176	1	e	e	NOUN
dpc-2653	176	2	and	and	CCONJ
dpc-2653	176	3	f.	f.	PROPN
dpc-2653	176	4	acute	acute	PROPN
dpc-2653	176	5	photo	photo	NOUN
dpc-2653	176	6	-	-	PUNCT
dpc-2653	176	7	onycholysis	onycholysis	NOUN
dpc-2653	176	8	in	in	ADP
dpc-2653	176	9	a	a	DET
dpc-2653	176	10	melanoma	melanoma	NOUN
dpc-2653	176	11	patient	patient	NOUN
dpc-2653	176	12	treated	treat	VERB
dpc-2653	176	13	with	with	ADP
dpc-2653	176	14	braf	braf	NOUN
dpc-2653	176	15	inhibitors	inhibitor	NOUN
dpc-2653	176	16	:	:	PUNCT
dpc-2653	176	17	clinical	clinical	ADJ
dpc-2653	176	18	and	and	CCONJ
dpc-2653	176	19	dermoscopic	dermoscopic	ADJ
dpc-2653	176	20	image	image	NOUN
dpc-2653	176	21	.	.	PUNCT
dpc-2653	177	1	the	the	DET
dpc-2653	177	2	nails	nail	NOUN
dpc-2653	177	3	were	be	AUX
dpc-2653	177	4	extremely	extremely	ADV
dpc-2653	177	5	painful	painful	ADJ
dpc-2653	177	6	with	with	ADP
dpc-2653	177	7	almost	almost	ADV
dpc-2653	177	8	total	total	ADJ
dpc-2653	177	9	detachment	detachment	NOUN
dpc-2653	177	10	of	of	ADP
dpc-2653	177	11	the	the	DET
dpc-2653	177	12	nail	nail	NOUN
dpc-2653	177	13	plate	plate	NOUN
dpc-2653	177	14	and	and	CCONJ
dpc-2653	177	15	presence	presence	NOUN
dpc-2653	177	16	of	of	ADP
dpc-2653	177	17	oozing	oozing	ADJ
dpc-2653	177	18	and	and	CCONJ
dpc-2653	177	19	subungual	subungual	ADJ
dpc-2653	177	20	hematoma	hematoma	NOUN
dpc-2653	177	21	.	.	PUNCT
dpc-2653	178	1	8	8	NUM
dpc-2653	178	2	review	review	NOUN
dpc-2653	178	3	|	|	ADV
dpc-2653	178	4	dermatol	dermatol	ADJ
dpc-2653	178	5	pract	pract	NOUN
dpc-2653	178	6	concept	concept	NOUN
dpc-2653	178	7	.	.	PUNCT
dpc-2653	179	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	179	2	complex	complex	ADJ
dpc-2653	179	3	,	,	PUNCT
dpc-2653	179	4	certain	certain	ADJ
dpc-2653	179	5	types	type	NOUN
dpc-2653	179	6	of	of	ADP
dpc-2653	179	7	seizures	seizure	NOUN
dpc-2653	179	8	in	in	ADP
dpc-2653	179	9	adults	adult	NOUN
dpc-2653	179	10	and	and	CCONJ
dpc-2653	179	11	children	child	NOUN
dpc-2653	179	12	and	and	CCONJ
dpc-2653	179	13	prevention	prevention	NOUN
dpc-2653	179	14	of	of	ADP
dpc-2653	179	15	transplant	transplant	NOUN
dpc-2653	179	16	rejection	rejection	NOUN
dpc-2653	179	17	)	)	PUNCT
dpc-2653	179	18	,	,	PUNCT
dpc-2653	179	19	as	as	ADV
dpc-2653	179	20	well	well	ADV
dpc-2653	179	21	as	as	ADP
dpc-2653	179	22	temsirolimus	temsirolimus	NOUN
dpc-2653	179	23	(	(	PUNCT
dpc-2653	179	24	indicated	indicate	VERB
dpc-2653	179	25	in	in	ADP
dpc-2653	179	26	renal	renal	ADJ
dpc-2653	179	27	cell	cell	NOUN
dpc-2653	179	28	carcinoma	carcinoma	NOUN
dpc-2653	179	29	)	)	PUNCT
dpc-2653	179	30	,	,	PUNCT
dpc-2653	179	31	may	may	AUX
dpc-2653	179	32	cause	cause	VERB
dpc-2653	179	33	yellow	yellow	ADJ
dpc-2653	179	34	nail	nail	NOUN
dpc-2653	179	35	discoloration	discoloration	NOUN
dpc-2653	179	36	,	,	PUNCT
dpc-2653	179	37	paronychia	paronychia	NOUN
dpc-2653	179	38	,	,	PUNCT
dpc-2653	179	39	pyogenic	pyogenic	ADJ
dpc-2653	179	40	granuloma	granuloma	NOUN
dpc-2653	179	41	,	,	PUNCT
dpc-2653	179	42	slower	slow	ADJ
dpc-2653	179	43	growth	growth	NOUN
dpc-2653	179	44	rate	rate	NOUN
dpc-2653	179	45	-	-	PUNCT
dpc-2653	179	46	thin	thin	ADJ
dpc-2653	179	47	nails	nail	NOUN
dpc-2653	179	48	,	,	PUNCT
dpc-2653	179	49	mild	mild	ADJ
dpc-2653	179	50	onycholysis	onycholysis	NOUN
dpc-2653	179	51	and	and	CCONJ
dpc-2653	179	52	brittle	brittle	ADJ
dpc-2653	179	53	nails	nail	NOUN
dpc-2653	180	1	[	[	X
dpc-2653	180	2	38	38	NUM
dpc-2653	180	3	]	]	PUNCT
dpc-2653	180	4	(	(	PUNCT
dpc-2653	180	5	table	table	NOUN
dpc-2653	180	6	3	3	NUM
dpc-2653	180	7	)	)	PUNCT
dpc-2653	180	8	.	.	PUNCT
dpc-2653	181	1	ret	ret	PROPN
dpc-2653	181	2	inhibitor	inhibitor	PROPN
dpc-2653	181	3	ret	ret	PROPN
dpc-2653	181	4	inhibitors	inhibitor	NOUN
dpc-2653	181	5	 	 	SPACE
dpc-2653	181	6	are	be	AUX
dpc-2653	181	7	targeted	target	VERB
dpc-2653	181	8	therapies	therapy	NOUN
dpc-2653	181	9	used	use	VERB
dpc-2653	181	10	on	on	ADP
dpc-2653	181	11	tumors	tumor	NOUN
dpc-2653	181	12	characterized	characterize	VERB
dpc-2653	181	13	by	by	ADP
dpc-2653	181	14	activated	activated	ADJ
dpc-2653	181	15	alterations	alteration	NOUN
dpc-2653	181	16	in	in	ADP
dpc-2653	181	17	the	the	DET
dpc-2653	181	18	 	 	SPACE
dpc-2653	181	19	ret	ret	PROPN
dpc-2653	181	20	proto	proto	NOUN
dpc-2653	181	21	-	-	PUNCT
dpc-2653	181	22	oncogene	oncogene	NOUN
dpc-2653	181	23	.	.	PUNCT
dpc-2653	182	1	these	these	PRON
dpc-2653	182	2	include	include	VERB
dpc-2653	182	3	non	non	ADJ
dpc-2653	182	4	-	-	ADJ
dpc-2653	182	5	small	small	ADJ
dpc-2653	182	6	cell	cell	NOUN
dpc-2653	182	7	lung	lung	NOUN
dpc-2653	182	8	cancer	cancer	NOUN
dpc-2653	182	9	(	(	PUNCT
dpc-2653	182	10	nsclc	nsclc	NOUN
dpc-2653	182	11	)	)	PUNCT
dpc-2653	182	12	,	,	PUNCT
dpc-2653	182	13	medullary	medullary	ADJ
dpc-2653	182	14	thyroid	thyroid	NOUN
dpc-2653	182	15	cancer	cancer	NOUN
dpc-2653	182	16	and	and	CCONJ
dpc-2653	182	17	papillary	papillary	ADJ
dpc-2653	182	18	thyroid	thyroid	NOUN
dpc-2653	182	19	cancer	cancer	NOUN
dpc-2653	182	20	.	.	PUNCT
dpc-2653	183	1	treatment	treatment	NOUN
dpc-2653	183	2	)	)	PUNCT
dpc-2653	183	3	have	have	AUX
dpc-2653	183	4	been	be	AUX
dpc-2653	183	5	associated	associate	VERB
dpc-2653	183	6	with	with	ADP
dpc-2653	183	7	paronychia	paronychia	PROPN
dpc-2653	183	8	,	,	PUNCT
dpc-2653	183	9	pyogenic	pyogenic	ADJ
dpc-2653	183	10	granuloma	granuloma	NOUN
dpc-2653	183	11	,	,	PUNCT
dpc-2653	183	12	slower	slow	ADJ
dpc-2653	183	13	growth	growth	NOUN
dpc-2653	183	14	rate	rate	NOUN
dpc-2653	183	15	,	,	PUNCT
dpc-2653	183	16	mild	mild	ADJ
dpc-2653	183	17	onycholysis	onycholysis	NOUN
dpc-2653	183	18	and	and	CCONJ
dpc-2653	183	19	brittle	brittle	ADJ
dpc-2653	183	20	nails	nail	NOUN
dpc-2653	183	21	[	[	X
dpc-2653	183	22	38	38	NUM
dpc-2653	183	23	,	,	PUNCT
dpc-2653	183	24	41	41	NUM
dpc-2653	183	25	]	]	PUNCT
dpc-2653	183	26	.	.	PUNCT
dpc-2653	184	1	m	m	NOUN
dpc-2653	184	2	-	-	PUNCT
dpc-2653	184	3	tor	tor	NOUN
dpc-2653	184	4	inhibitors	inhibitor	NOUN
dpc-2653	184	5	the	the	DET
dpc-2653	184	6	mammalian	mammalian	ADJ
dpc-2653	184	7	target	target	NOUN
dpc-2653	184	8	of	of	ADP
dpc-2653	184	9	rapamycin	rapamycin	PROPN
dpc-2653	184	10	regulates	regulate	VERB
dpc-2653	184	11	cellular	cellular	ADJ
dpc-2653	184	12	metabolism	metabolism	NOUN
dpc-2653	184	13	,	,	PUNCT
dpc-2653	184	14	growth	growth	NOUN
dpc-2653	184	15	and	and	CCONJ
dpc-2653	184	16	proliferation	proliferation	NOUN
dpc-2653	184	17	by	by	ADP
dpc-2653	184	18	forming	form	VERB
dpc-2653	184	19	and	and	CCONJ
dpc-2653	184	20	signalling	signal	VERB
dpc-2653	184	21	through	through	ADP
dpc-2653	184	22	two	two	NUM
dpc-2653	184	23	protein	protein	NOUN
dpc-2653	184	24	complexes	complex	NOUN
dpc-2653	184	25	,	,	PUNCT
dpc-2653	184	26	mtorc1	mtorc1	NOUN
dpc-2653	184	27	and	and	CCONJ
dpc-2653	184	28	mtorc2	mtorc2	NOUN
dpc-2653	185	1	[	[	X
dpc-2653	185	2	38	38	NUM
dpc-2653	185	3	]	]	PUNCT
dpc-2653	185	4	.	.	PUNCT
dpc-2653	186	1	everolimus	everolimus	PROPN
dpc-2653	186	2	(	(	PUNCT
dpc-2653	186	3	indicated	indicate	VERB
dpc-2653	186	4	in	in	ADP
dpc-2653	186	5	advanced	advanced	ADJ
dpc-2653	186	6	renal	renal	ADJ
dpc-2653	186	7	cell	cell	NOUN
dpc-2653	186	8	carcinoma	carcinoma	NOUN
dpc-2653	186	9	,	,	PUNCT
dpc-2653	186	10	advanced	advanced	ADJ
dpc-2653	186	11	breast	breast	NOUN
dpc-2653	186	12	cancer	cancer	NOUN
dpc-2653	186	13	,	,	PUNCT
dpc-2653	186	14	pancreas	pancrea	NOUN
dpc-2653	186	15	,	,	PUNCT
dpc-2653	186	16	stomach	stomach	NOUN
dpc-2653	186	17	,	,	PUNCT
dpc-2653	186	18	intestines	intestine	NOUN
dpc-2653	186	19	,	,	PUNCT
dpc-2653	186	20	lungs	lung	NOUN
dpc-2653	186	21	,	,	PUNCT
dpc-2653	186	22	subependymal	subependymal	ADJ
dpc-2653	186	23	giant	giant	ADJ
dpc-2653	186	24	cell	cell	NOUN
dpc-2653	186	25	astrocytoma	astrocytoma	NOUN
dpc-2653	186	26	,	,	PUNCT
dpc-2653	186	27	tuberous	tuberous	ADJ
dpc-2653	186	28	sclerosis	sclerosis	NOUN
dpc-2653	186	29	table	table	NOUN
dpc-2653	186	30	3	3	NUM
dpc-2653	186	31	.	.	X
dpc-2653	186	32	main	main	ADJ
dpc-2653	186	33	nail	nail	NOUN
dpc-2653	186	34	toxicities	toxicity	NOUN
dpc-2653	186	35	induced	induce	VERB
dpc-2653	186	36	by	by	ADP
dpc-2653	186	37	targeted	target	VERB
dpc-2653	186	38	anticancer	anticancer	NOUN
dpc-2653	186	39	therapies	therapy	NOUN
dpc-2653	187	1	[	[	X
dpc-2653	187	2	38	38	NUM
dpc-2653	187	3	]	]	PUNCT
dpc-2653	187	4	.	.	PUNCT
dpc-2653	188	1	drug	drug	NOUN
dpc-2653	188	2	class	class	NOUN
dpc-2653	188	3	target	target	NOUN
dpc-2653	188	4	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	188	5	drugs	drug	NOUN
dpc-2653	188	6	nail	nail	NOUN
dpc-2653	188	7	disorders	disorder	NOUN
dpc-2653	188	8	anti	anti	ADJ
dpc-2653	188	9	-	-	ADJ
dpc-2653	188	10	egfr	egfr	ADJ
dpc-2653	188	11	egfr	egfr	NOUN
dpc-2653	188	12	(	(	PUNCT
dpc-2653	188	13	her1	her1	NOUN
dpc-2653	188	14	or	or	CCONJ
dpc-2653	188	15	erbb1	erbb1	NOUN
dpc-2653	188	16	)	)	PUNCT
dpc-2653	188	17	cetuximab	cetuximab	NOUN
dpc-2653	188	18	panitumumab	panitumumab	NOUN
dpc-2653	188	19	,	,	PUNCT
dpc-2653	188	20	erlotinib	erlotinib	NOUN
dpc-2653	188	21	gefitinib	gefitinib	NOUN
dpc-2653	188	22	necitumumab	necitumumab	VERB
dpc-2653	188	23	paronychia	paronychia	PROPN
dpc-2653	188	24	pyogenic	pyogenic	ADJ
dpc-2653	188	25	granuloma	granuloma	NOUN
dpc-2653	188	26	slower	slow	ADJ
dpc-2653	188	27	growth	growth	NOUN
dpc-2653	188	28	rate	rate	NOUN
dpc-2653	188	29	mild	mild	ADJ
dpc-2653	188	30	onycholysis	onycholysis	NOUN
dpc-2653	188	31	thin	thin	ADJ
dpc-2653	188	32	nails	nail	NOUN
dpc-2653	188	33	brittle	brittle	ADJ
dpc-2653	188	34	nails	nail	NOUN
dpc-2653	188	35	anti	anti	ADJ
dpc-2653	188	36	-	-	ADJ
dpc-2653	188	37	her2	her2	ADJ
dpc-2653	188	38	her2	her2	VERB
dpc-2653	188	39	trastuzumab	trastuzumab	NOUN
dpc-2653	188	40	thin	thin	ADJ
dpc-2653	188	41	nails	nail	NOUN
dpc-2653	188	42	anti	anti	ADJ
dpc-2653	188	43	-	-	ADJ
dpc-2653	188	44	her	her	PRON
dpc-2653	188	45	her1	her1	NOUN
dpc-2653	188	46	-	-	PUNCT
dpc-2653	188	47	4	4	NUM
dpc-2653	188	48	(	(	PUNCT
dpc-2653	188	49	erbb1	erbb1	NOUN
dpc-2653	188	50	-	-	PUNCT
dpc-2653	188	51	4	4	NUM
dpc-2653	188	52	)	)	PUNCT
dpc-2653	188	53	lapatinib	lapatinib	VERB
dpc-2653	188	54	afatinib	afatinib	PROPN
dpc-2653	188	55	dacomitinib	dacomitinib	PROPN
dpc-2653	188	56	paronychia	paronychia	VERB
dpc-2653	188	57	pyogenic	pyogenic	ADJ
dpc-2653	188	58	granuloma	granuloma	NOUN
dpc-2653	188	59	slower	slow	ADJ
dpc-2653	188	60	growth	growth	NOUN
dpc-2653	188	61	rate	rate	NOUN
dpc-2653	188	62	mild	mild	ADJ
dpc-2653	188	63	onycholysis	onycholysis	NOUN
dpc-2653	188	64	thin	thin	ADJ
dpc-2653	188	65	nails	nail	NOUN
dpc-2653	188	66	brittle	brittle	ADJ
dpc-2653	188	67	nails	nail	NOUN
dpc-2653	188	68	anti	anti	ADJ
dpc-2653	188	69	-	-	ADJ
dpc-2653	188	70	mek	mek	ADJ
dpc-2653	188	71	mek	mek	PROPN
dpc-2653	188	72	1/2	1/2	NUM
dpc-2653	188	73	trametinib	trametinib	NOUN
dpc-2653	188	74	cobimetinib	cobimetinib	PROPN
dpc-2653	188	75	selumetinib	selumetinib	VERB
dpc-2653	188	76	paronychia	paronychia	PROPN
dpc-2653	188	77	pyogenic	pyogenic	ADJ
dpc-2653	188	78	granuloma	granuloma	NOUN
dpc-2653	188	79	slower	slow	ADJ
dpc-2653	188	80	growth	growth	NOUN
dpc-2653	188	81	rate	rate	NOUN
dpc-2653	188	82	mild	mild	ADJ
dpc-2653	188	83	onycholysis	onycholysis	NOUN
dpc-2653	188	84	brittle	brittle	ADJ
dpc-2653	188	85	nails	nail	NOUN
dpc-2653	188	86	mtor	mtor	NOUN
dpc-2653	188	87	inhibitors	inhibitor	NOUN
dpc-2653	188	88	mtor	mtor	PROPN
dpc-2653	188	89	everolimus	everolimus	PROPN
dpc-2653	188	90	temsirolimus	temsirolimus	PROPN
dpc-2653	188	91	paronychia	paronychia	PROPN
dpc-2653	188	92	pyogenic	pyogenic	ADJ
dpc-2653	188	93	granuloma	granuloma	NOUN
dpc-2653	188	94	yellow	yellow	ADJ
dpc-2653	188	95	nail	nail	NOUN
dpc-2653	188	96	discoloration	discoloration	NOUN
dpc-2653	188	97	slower	slow	ADJ
dpc-2653	188	98	growth	growth	NOUN
dpc-2653	188	99	rate	rate	NOUN
dpc-2653	188	100	-	-	PUNCT
dpc-2653	188	101	thin	thin	ADJ
dpc-2653	188	102	nails	nail	NOUN
dpc-2653	188	103	mild	mild	ADJ
dpc-2653	188	104	onycholysis	onycholysis	NOUN
dpc-2653	188	105	brittle	brittle	ADJ
dpc-2653	188	106	nails	nail	NOUN
dpc-2653	188	107	angiogenesis	angiogenesis	NOUN
dpc-2653	188	108	multikinase	multikinase	NOUN
dpc-2653	188	109	inhibitors	inhibitor	NOUN
dpc-2653	188	110	vegrf	vegrf	VERB
dpc-2653	188	111	1	1	NUM
dpc-2653	188	112	-	-	SYM
dpc-2653	188	113	3	3	NUM
dpc-2653	188	114	pdgfr	pdgfr	ADJ
dpc-2653	188	115	α	α	NOUN
dpc-2653	188	116	/	/	SYM
dpc-2653	188	117	β	β	NOUN
dpc-2653	188	118	and	and	CCONJ
dpc-2653	188	119	other	other	ADJ
dpc-2653	188	120	molecular	molecular	ADJ
dpc-2653	188	121	targets	target	NOUN
dpc-2653	188	122	sunitinib	sunitinib	NOUN
dpc-2653	188	123	sorafenib	sorafenib	NOUN
dpc-2653	188	124	cabozantinib	cabozantinib	PROPN
dpc-2653	188	125	axitinib	axitinib	PROPN
dpc-2653	188	126	pazotinib	pazotinib	PROPN
dpc-2653	188	127	regorafenib	regorafenib	PROPN
dpc-2653	188	128	splinter	splinter	VERB
dpc-2653	188	129	subungual	subungual	ADJ
dpc-2653	188	130	hemorrhage	hemorrhage	NOUN
dpc-2653	188	131	brittle	brittle	ADJ
dpc-2653	188	132	nails	nail	NOUN
dpc-2653	188	133	ret	ret	NOUN
dpc-2653	188	134	inhibitor	inhibitor	NOUN
dpc-2653	189	1	egfr	egfr	NOUN
dpc-2653	189	2	vegfr	vegfr	PROPN
dpc-2653	189	3	2/3	2/3	NUM
dpc-2653	189	4	ret	ret	NOUN
dpc-2653	189	5	vandetanib	vandetanib	NOUN
dpc-2653	189	6	paronychia	paronychia	VERB
dpc-2653	189	7	pyogenic	pyogenic	ADJ
dpc-2653	189	8	granuloma	granuloma	ADJ
dpc-2653	189	9	photoonycholysis	photoonycholysis	NOUN
dpc-2653	189	10	splinter	splinter	VERB
dpc-2653	189	11	subungual	subungual	ADJ
dpc-2653	189	12	hemorrhage	hemorrhage	NOUN
dpc-2653	189	13	bcr	bcr	PROPN
dpc-2653	189	14	-	-	ADJ
dpc-2653	189	15	abl	abl	PROPN
dpc-2653	189	16	inhibitor	inhibitor	NOUN
dpc-2653	189	17	bcr	bcr	PROPN
dpc-2653	189	18	-	-	PROPN
dpc-2653	189	19	abl	abl	ADJ
dpc-2653	189	20	c	c	NOUN
dpc-2653	189	21	-	-	PUNCT
dpc-2653	189	22	kit	kit	ADJ
dpc-2653	189	23	pdgfr	pdgfr	ADJ
dpc-2653	189	24	imatinib	imatinib	NOUN
dpc-2653	189	25	melanonychia	melanonychia	VERB
dpc-2653	189	26	lichenoid	lichenoid	PROPN
dpc-2653	189	27	reactions	reaction	NOUN
dpc-2653	189	28	bruton	bruton	PROPN
dpc-2653	189	29	inhibitors	inhibitors	PROPN
dpc-2653	189	30	bruton	bruton	PROPN
dpc-2653	189	31	tyrosine	tyrosine	PROPN
dpc-2653	189	32	kinase	kinase	PROPN
dpc-2653	189	33	ibrutinib	ibrutinib	PROPN
dpc-2653	190	1	brittle	brittle	ADJ
dpc-2653	190	2	nails	nail	NOUN
dpc-2653	190	3	onychoschizia	onychoschizia	NOUN
dpc-2653	190	4	onychorrhexis	onychorrhexi	VERB
dpc-2653	190	5	mild	mild	ADJ
dpc-2653	190	6	onycholysis	onycholysis	NOUN
dpc-2653	190	7	review	review	NOUN
dpc-2653	190	8	|	|	ADV
dpc-2653	190	9	dermatol	dermatol	ADJ
dpc-2653	190	10	pract	pract	NOUN
dpc-2653	190	11	concept	concept	NOUN
dpc-2653	190	12	.	.	PUNCT
dpc-2653	191	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	191	2	9	9	NUM
dpc-2653	191	3	very	very	ADV
dpc-2653	191	4	rare	rare	ADJ
dpc-2653	192	1	but	but	CCONJ
dpc-2653	192	2	may	may	AUX
dpc-2653	192	3	provoke	provoke	VERB
dpc-2653	192	4	a	a	DET
dpc-2653	192	5	destruction	destruction	NOUN
dpc-2653	192	6	of	of	ADP
dpc-2653	192	7	the	the	DET
dpc-2653	192	8	matrix	matrix	NOUN
dpc-2653	192	9	and	and	CCONJ
dpc-2653	192	10	a	a	DET
dpc-2653	192	11	subsequent	subsequent	ADJ
dpc-2653	192	12	scar	scar	NOUN
dpc-2653	192	13	formation	formation	NOUN
dpc-2653	192	14	.	.	PUNCT
dpc-2653	193	1	immunotherapy	immunotherapy	NOUN
dpc-2653	193	2	(	(	PUNCT
dpc-2653	193	3	figure	figure	NOUN
dpc-2653	193	4	3	3	NUM
dpc-2653	193	5	)	)	PUNCT
dpc-2653	193	6	the	the	DET
dpc-2653	193	7	immune	immune	ADJ
dpc-2653	193	8	system	system	NOUN
dpc-2653	193	9	,	,	PUNCT
dpc-2653	193	10	as	as	ADP
dpc-2653	193	11	part	part	NOUN
dpc-2653	193	12	of	of	ADP
dpc-2653	193	13	its	its	PRON
dpc-2653	193	14	normal	normal	ADJ
dpc-2653	193	15	function	function	NOUN
dpc-2653	193	16	,	,	PUNCT
dpc-2653	193	17	detects	detect	NOUN
dpc-2653	193	18	and	and	CCONJ
dpc-2653	193	19	destroys	destroy	VERB
dpc-2653	193	20	abnormal	abnormal	ADJ
dpc-2653	193	21	cells	cell	NOUN
dpc-2653	193	22	and	and	CCONJ
dpc-2653	193	23	prevents	prevent	VERB
dpc-2653	193	24	or	or	CCONJ
dpc-2653	193	25	suppresses	suppress	VERB
dpc-2653	193	26	cancer	cancer	NOUN
dpc-2653	193	27	growth	growth	NOUN
dpc-2653	193	28	.	.	PUNCT
dpc-2653	194	1	despite	despite	SCONJ
dpc-2653	194	2	that	that	PRON
dpc-2653	194	3	,	,	PUNCT
dpc-2653	194	4	cancer	cancer	NOUN
dpc-2653	194	5	cells	cell	NOUN
dpc-2653	194	6	have	have	VERB
dpc-2653	194	7	ways	way	NOUN
dpc-2653	194	8	to	to	PART
dpc-2653	194	9	evade	evade	VERB
dpc-2653	194	10	the	the	DET
dpc-2653	194	11	immune	immune	ADJ
dpc-2653	194	12	system	system	NOUN
dpc-2653	194	13	.	.	PUNCT
dpc-2653	195	1	they	they	PRON
dpc-2653	195	2	may	may	AUX
dpc-2653	195	3	present	present	VERB
dpc-2653	195	4	genetic	genetic	ADJ
dpc-2653	195	5	changes	change	NOUN
dpc-2653	195	6	that	that	PRON
dpc-2653	195	7	make	make	VERB
dpc-2653	195	8	them	they	PRON
dpc-2653	195	9	less	less	ADV
dpc-2653	195	10	visible	visible	ADJ
dpc-2653	195	11	to	to	ADP
dpc-2653	195	12	the	the	DET
dpc-2653	195	13	immune	immune	ADJ
dpc-2653	195	14	system	system	NOUN
dpc-2653	195	15	,	,	PUNCT
dpc-2653	195	16	have	have	VERB
dpc-2653	195	17	proteins	protein	NOUN
dpc-2653	195	18	on	on	ADP
dpc-2653	195	19	their	their	PRON
dpc-2653	195	20	surface	surface	NOUN
dpc-2653	195	21	that	that	PRON
dpc-2653	195	22	turn	turn	VERB
dpc-2653	195	23	off	off	ADP
dpc-2653	195	24	immune	immune	ADJ
dpc-2653	195	25	cells	cell	NOUN
dpc-2653	195	26	or	or	CCONJ
dpc-2653	195	27	affect	affect	VERB
dpc-2653	195	28	the	the	DET
dpc-2653	195	29	normal	normal	ADJ
dpc-2653	195	30	cells	cell	NOUN
dpc-2653	195	31	surrounding	surround	VERB
dpc-2653	195	32	a	a	DET
dpc-2653	195	33	tumor	tumor	NOUN
dpc-2653	195	34	in	in	ADP
dpc-2653	195	35	a	a	DET
dpc-2653	195	36	way	way	NOUN
dpc-2653	195	37	that	that	PRON
dpc-2653	195	38	they	they	PRON
dpc-2653	195	39	interfere	interfere	VERB
dpc-2653	195	40	with	with	ADP
dpc-2653	195	41	the	the	DET
dpc-2653	195	42	immune	immune	ADJ
dpc-2653	195	43	response	response	NOUN
dpc-2653	195	44	to	to	ADP
dpc-2653	195	45	cancer	cancer	NOUN
dpc-2653	195	46	cells	cell	NOUN
dpc-2653	195	47	.	.	PUNCT
dpc-2653	196	1	the	the	DET
dpc-2653	196	2	most	most	ADV
dpc-2653	196	3	prevalent	prevalent	ADJ
dpc-2653	196	4	immune	immune	NOUN
dpc-2653	196	5	-	-	PUNCT
dpc-2653	196	6	related	relate	VERB
dpc-2653	196	7	dermatologic	dermatologic	ADJ
dpc-2653	196	8	adverse	adverse	ADJ
dpc-2653	196	9	events	event	NOUN
dpc-2653	196	10	(	(	PUNCT
dpc-2653	196	11	irae	irae	NOUN
dpc-2653	196	12	)	)	PUNCT
dpc-2653	196	13	are	be	AUX
dpc-2653	196	14	triggered	trigger	VERB
dpc-2653	196	15	by	by	ADP
dpc-2653	196	16	immune	immune	ADJ
dpc-2653	196	17	checkpoint	checkpoint	NOUN
dpc-2653	196	18	inhibitors	inhibitor	NOUN
dpc-2653	196	19	(	(	PUNCT
dpc-2653	196	20	cpis	cpis	ADJ
dpc-2653	196	21	)	)	PUNCT
dpc-2653	196	22	.	.	PUNCT
dpc-2653	197	1	immune	immune	ADJ
dpc-2653	197	2	checkpoint	checkpoint	NOUN
dpc-2653	197	3	inhibitors	inhibitor	NOUN
dpc-2653	197	4	(	(	PUNCT
dpc-2653	197	5	cpis	cpis	ADJ
dpc-2653	197	6	)	)	PUNCT
dpc-2653	197	7	are	be	AUX
dpc-2653	197	8	targeted	target	VERB
dpc-2653	197	9	molecules	molecule	NOUN
dpc-2653	197	10	that	that	PRON
dpc-2653	197	11	modulate	modulate	VERB
dpc-2653	197	12	the	the	DET
dpc-2653	197	13	immune	immune	ADJ
dpc-2653	197	14	system	system	NOUN
dpc-2653	197	15	,	,	PUNCT
dpc-2653	197	16	assist	assist	VERB
dpc-2653	197	17	with	with	ADP
dpc-2653	197	18	self	self	NOUN
dpc-2653	197	19	-	-	PUNCT
dpc-2653	197	20	tolerance	tolerance	NOUN
dpc-2653	197	21	,	,	PUNCT
dpc-2653	197	22	and	and	CCONJ
dpc-2653	197	23	minimize	minimize	VERB
dpc-2653	197	24	collateral	collateral	ADJ
dpc-2653	197	25	tissue	tissue	NOUN
dpc-2653	197	26	damage	damage	NOUN
dpc-2653	197	27	when	when	SCONJ
dpc-2653	197	28	immune	immune	ADJ
dpc-2653	197	29	responses	response	NOUN
dpc-2653	197	30	are	be	AUX
dpc-2653	197	31	activated	activate	VERB
dpc-2653	197	32	.	.	PUNCT
dpc-2653	198	1	these	these	DET
dpc-2653	198	2	checkpoints	checkpoint	NOUN
dpc-2653	198	3	are	be	AUX
dpc-2653	198	4	a	a	DET
dpc-2653	198	5	normal	normal	ADJ
dpc-2653	198	6	part	part	NOUN
dpc-2653	198	7	of	of	ADP
dpc-2653	198	8	the	the	DET
dpc-2653	198	9	immune	immune	ADJ
dpc-2653	198	10	system	system	NOUN
dpc-2653	198	11	and	and	CCONJ
dpc-2653	198	12	keep	keep	VERB
dpc-2653	198	13	immune	immune	ADJ
dpc-2653	198	14	responses	response	NOUN
dpc-2653	198	15	from	from	ADP
dpc-2653	198	16	being	be	AUX
dpc-2653	198	17	too	too	ADV
dpc-2653	198	18	strong	strong	ADJ
dpc-2653	198	19	.	.	PUNCT
dpc-2653	199	1	by	by	ADP
dpc-2653	199	2	blocking	block	VERB
dpc-2653	199	3	them	they	PRON
dpc-2653	199	4	,	,	PUNCT
dpc-2653	199	5	these	these	DET
dpc-2653	199	6	drugs	drug	NOUN
dpc-2653	199	7	allow	allow	VERB
dpc-2653	199	8	immune	immune	ADJ
dpc-2653	199	9	cells	cell	NOUN
dpc-2653	199	10	to	to	PART
dpc-2653	199	11	respond	respond	VERB
dpc-2653	199	12	more	more	ADV
dpc-2653	199	13	efficiently	efficiently	ADV
dpc-2653	199	14	to	to	ADP
dpc-2653	199	15	cancer	cancer	NOUN
dpc-2653	199	16	.	.	PUNCT
dpc-2653	200	1	this	this	DET
dpc-2653	200	2	blockade	blockade	NOUN
dpc-2653	200	3	has	have	AUX
dpc-2653	200	4	been	be	AUX
dpc-2653	200	5	associated	associate	VERB
dpc-2653	200	6	with	with	ADP
dpc-2653	200	7	autoimmune	autoimmune	ADJ
dpc-2653	200	8	-	-	PUNCT
dpc-2653	200	9	like	like	ADJ
dpc-2653	200	10	toxicities	toxicity	NOUN
dpc-2653	200	11	,	,	PUNCT
dpc-2653	200	12	named	name	VERB
dpc-2653	200	13	immune	immune	NOUN
dpc-2653	200	14	-	-	PUNCT
dpc-2653	200	15	related	relate	VERB
dpc-2653	200	16	adverse	adverse	ADJ
dpc-2653	200	17	events	event	NOUN
dpc-2653	200	18	(	(	PUNCT
dpc-2653	200	19	irae	irae	NOUN
dpc-2653	200	20	)	)	PUNCT
dpc-2653	201	1	[	[	X
dpc-2653	201	2	24	24	NUM
dpc-2653	201	3	,	,	PUNCT
dpc-2653	201	4	43	43	NUM
dpc-2653	201	5	]	]	PUNCT
dpc-2653	201	6	.	.	PUNCT
dpc-2653	202	1	vandetanib	vandetanib	PROPN
dpc-2653	202	2	is	be	AUX
dpc-2653	202	3	an	an	DET
dpc-2653	202	4	oral	oral	ADJ
dpc-2653	202	5	multikinase	multikinase	NOUN
dpc-2653	202	6	inhibitor	inhibitor	NOUN
dpc-2653	202	7	which	which	PRON
dpc-2653	202	8	targets	target	VERB
dpc-2653	202	9	the	the	DET
dpc-2653	202	10	ret	ret	PROPN
dpc-2653	202	11	,	,	PUNCT
dpc-2653	202	12	proto	proto	NOUN
dpc-2653	202	13	-	-	PUNCT
dpc-2653	202	14	oncogene	oncogene	ADJ
dpc-2653	202	15	,	,	PUNCT
dpc-2653	202	16	egf	egf	PROPN
dpc-2653	202	17	and	and	CCONJ
dpc-2653	202	18	vegf	vegf	PROPN
dpc-2653	202	19	receptors	receptor	NOUN
dpc-2653	202	20	.	.	PUNCT
dpc-2653	203	1	the	the	DET
dpc-2653	203	2	most	most	ADV
dpc-2653	203	3	prevalent	prevalent	ADJ
dpc-2653	203	4	nail	nail	NOUN
dpc-2653	203	5	adverse	adverse	ADJ
dpc-2653	203	6	event	event	NOUN
dpc-2653	203	7	associated	associate	VERB
dpc-2653	203	8	with	with	ADP
dpc-2653	203	9	vandetanib	vandetanib	NOUN
dpc-2653	203	10	therapy	therapy	NOUN
dpc-2653	203	11	is	be	AUX
dpc-2653	203	12	subungual	subungual	ADJ
dpc-2653	203	13	hemorrhage	hemorrhage	NOUN
dpc-2653	203	14	(	(	PUNCT
dpc-2653	203	15	due	due	ADP
dpc-2653	203	16	to	to	PART
dpc-2653	203	17	vegfr	vegfr	ADJ
dpc-2653	203	18	inhibition	inhibition	NOUN
dpc-2653	203	19	)	)	PUNCT
dpc-2653	203	20	,	,	PUNCT
dpc-2653	203	21	paronychia	paronychia	PROPN
dpc-2653	203	22	/	/	SYM
dpc-2653	203	23	pyogenic	pyogenic	ADJ
dpc-2653	203	24	granuloma	granuloma	NOUN
dpc-2653	203	25	(	(	PUNCT
dpc-2653	203	26	egfr	egfr	ADJ
dpc-2653	203	27	inhibition	inhibition	NOUN
dpc-2653	203	28	)	)	PUNCT
dpc-2653	203	29	and	and	CCONJ
dpc-2653	203	30	a	a	DET
dpc-2653	203	31	painful	painful	ADJ
dpc-2653	203	32	type	type	NOUN
dpc-2653	203	33	1	1	NUM
dpc-2653	203	34	photo	photo	NOUN
dpc-2653	203	35	-	-	PUNCT
dpc-2653	203	36	onycholysis	onycholysis	NOUN
dpc-2653	203	37	[	[	X
dpc-2653	203	38	38	38	NUM
dpc-2653	203	39	]	]	PUNCT
dpc-2653	203	40	(	(	PUNCT
dpc-2653	203	41	table	table	NOUN
dpc-2653	203	42	3	3	NUM
dpc-2653	203	43	)	)	PUNCT
dpc-2653	203	44	.	.	PUNCT
dpc-2653	204	1	patients	patient	NOUN
dpc-2653	204	2	should	should	AUX
dpc-2653	204	3	be	be	AUX
dpc-2653	204	4	informed	inform	VERB
dpc-2653	204	5	about	about	ADP
dpc-2653	204	6	uva	uva	PROPN
dpc-2653	204	7	/	/	SYM
dpc-2653	204	8	uvb	uvb	ADJ
dpc-2653	204	9	photo	photo	NOUN
dpc-2653	204	10	-	-	PUNCT
dpc-2653	204	11	protection	protection	NOUN
dpc-2653	204	12	.	.	PUNCT
dpc-2653	205	1	bcr	bcr	NOUN
dpc-2653	205	2	-	-	ADJ
dpc-2653	205	3	abl	abl	PROPN
dpc-2653	205	4	inhibitors	inhibitor	NOUN
dpc-2653	205	5	bcr	bcr	PROPN
dpc-2653	205	6	-	-	PUNCT
dpc-2653	205	7	abl	abl	PROPN
dpc-2653	205	8	is	be	AUX
dpc-2653	205	9	a	a	DET
dpc-2653	205	10	gene	gene	NOUN
dpc-2653	205	11	produced	produce	VERB
dpc-2653	205	12	by	by	ADP
dpc-2653	205	13	the	the	DET
dpc-2653	205	14	bcr	bcr	PROPN
dpc-2653	205	15	gene	gene	NOUN
dpc-2653	205	16	and	and	CCONJ
dpc-2653	205	17	the	the	DET
dpc-2653	205	18	c	c	PROPN
dpc-2653	205	19	-	-	PUNCT
dpc-2653	205	20	abl	abl	NOUN
dpc-2653	205	21	proto	proto	NOUN
dpc-2653	205	22	-	-	PUNCT
dpc-2653	205	23	oncogene	oncogene	NOUN
dpc-2653	205	24	and	and	CCONJ
dpc-2653	205	25	is	be	AUX
dpc-2653	205	26	considered	consider	VERB
dpc-2653	205	27	to	to	PART
dpc-2653	205	28	be	be	AUX
dpc-2653	205	29	the	the	DET
dpc-2653	205	30	main	main	ADJ
dpc-2653	205	31	cause	cause	NOUN
dpc-2653	205	32	of	of	ADP
dpc-2653	205	33	chronic	chronic	ADJ
dpc-2653	205	34	myelogenous	myelogenous	ADJ
dpc-2653	205	35	leukemia	leukemia	NOUN
dpc-2653	205	36	(	(	PUNCT
dpc-2653	205	37	cml	cml	PROPN
dpc-2653	205	38	)	)	PUNCT
dpc-2653	205	39	,	,	PUNCT
dpc-2653	205	40	acute	acute	ADJ
dpc-2653	205	41	lymphocytic	lymphocytic	ADJ
dpc-2653	205	42	leukemia	leukemia	NOUN
dpc-2653	205	43	(	(	PUNCT
dpc-2653	205	44	all	all	PRON
dpc-2653	205	45	)	)	PUNCT
dpc-2653	205	46	that	that	PRON
dpc-2653	205	47	are	be	AUX
dpc-2653	205	48	philadelphia	philadelphia	PROPN
dpc-2653	205	49	chromosome	chromosome	NOUN
dpc-2653	205	50	-	-	PUNCT
dpc-2653	205	51	positive	positive	ADJ
dpc-2653	205	52	,	,	PUNCT
dpc-2653	205	53	certain	certain	ADJ
dpc-2653	205	54	types	type	NOUN
dpc-2653	205	55	of	of	ADP
dpc-2653	205	56	gastrointestinal	gastrointestinal	ADJ
dpc-2653	205	57	stromal	stromal	ADJ
dpc-2653	205	58	tumors	tumor	NOUN
dpc-2653	205	59	,	,	PUNCT
dpc-2653	205	60	hypereosinophilic	hypereosinophilic	ADJ
dpc-2653	205	61	syndrome	syndrome	NOUN
dpc-2653	205	62	,	,	PUNCT
dpc-2653	205	63	chronic	chronic	ADJ
dpc-2653	205	64	eosinophilic	eosinophilic	ADJ
dpc-2653	205	65	leukemia	leukemia	NOUN
dpc-2653	205	66	,	,	PUNCT
dpc-2653	205	67	systemic	systemic	ADJ
dpc-2653	205	68	mastocytosis	mastocytosis	NOUN
dpc-2653	205	69	and	and	CCONJ
dpc-2653	205	70	myelodysplastic	myelodysplastic	ADJ
dpc-2653	205	71	syndrome	syndrome	NOUN
dpc-2653	206	1	[	[	X
dpc-2653	206	2	38	38	NUM
dpc-2653	206	3	]	]	PUNCT
dpc-2653	206	4	.	.	PUNCT
dpc-2653	207	1	imatinib	imatinib	NOUN
dpc-2653	207	2	is	be	AUX
dpc-2653	207	3	an	an	DET
dpc-2653	207	4	oral	oral	ADJ
dpc-2653	207	5	medication	medication	NOUN
dpc-2653	207	6	of	of	ADP
dpc-2653	207	7	this	this	DET
dpc-2653	207	8	group	group	NOUN
dpc-2653	207	9	that	that	PRON
dpc-2653	207	10	may	may	AUX
dpc-2653	207	11	induce	induce	VERB
dpc-2653	207	12	melanonychia	melanonychia	NOUN
dpc-2653	207	13	and	and	CCONJ
dpc-2653	207	14	lichenoid	lichenoid	NOUN
dpc-2653	207	15	reactions	reaction	NOUN
dpc-2653	207	16	(	(	PUNCT
dpc-2653	207	17	table	table	NOUN
dpc-2653	207	18	3	3	NUM
dpc-2653	207	19	)	)	PUNCT
dpc-2653	207	20	.	.	PUNCT
dpc-2653	208	1	melanonychia	melanonychia	NOUN
dpc-2653	208	2	appears	appear	VERB
dpc-2653	208	3	1	1	NUM
dpc-2653	208	4	-	-	SYM
dpc-2653	208	5	2	2	NUM
dpc-2653	208	6	months	month	NOUN
dpc-2653	208	7	after	after	ADP
dpc-2653	208	8	treatment	treatment	NOUN
dpc-2653	208	9	initiation	initiation	NOUN
dpc-2653	208	10	.	.	PUNCT
dpc-2653	209	1	it	it	PRON
dpc-2653	209	2	results	result	VERB
dpc-2653	209	3	from	from	ADP
dpc-2653	209	4	the	the	DET
dpc-2653	209	5	direct	direct	ADJ
dpc-2653	209	6	toxic	toxic	ADJ
dpc-2653	209	7	action	action	NOUN
dpc-2653	209	8	of	of	ADP
dpc-2653	209	9	the	the	DET
dpc-2653	209	10	regimen	regiman	NOUN
dpc-2653	209	11	on	on	ADP
dpc-2653	209	12	the	the	DET
dpc-2653	209	13	melanocytes	melanocyte	NOUN
dpc-2653	209	14	of	of	ADP
dpc-2653	209	15	the	the	DET
dpc-2653	209	16	nail	nail	NOUN
dpc-2653	209	17	matrix	matrix	NOUN
dpc-2653	209	18	,	,	PUNCT
dpc-2653	209	19	with	with	ADP
dpc-2653	209	20	secondary	secondary	ADJ
dpc-2653	209	21	melanin	melanin	NOUN
dpc-2653	209	22	production	production	NOUN
dpc-2653	209	23	.	.	PUNCT
dpc-2653	210	1	melanonychia	melanonychia	NOUN
dpc-2653	210	2	striate	striate	NOUN
dpc-2653	210	3	,	,	PUNCT
dpc-2653	210	4	as	as	ADV
dpc-2653	210	5	well	well	ADV
dpc-2653	210	6	as	as	ADP
dpc-2653	210	7	total	total	ADJ
dpc-2653	210	8	melanonychia	melanonychia	NOUN
dpc-2653	210	9	do	do	AUX
dpc-2653	210	10	not	not	PART
dpc-2653	210	11	require	require	VERB
dpc-2653	210	12	any	any	DET
dpc-2653	210	13	treatment	treatment	NOUN
dpc-2653	210	14	.	.	PUNCT
dpc-2653	211	1	they	they	PRON
dpc-2653	211	2	regress	regress	VERB
dpc-2653	211	3	spontaneously	spontaneously	ADV
dpc-2653	211	4	several	several	ADJ
dpc-2653	211	5	months	month	NOUN
dpc-2653	211	6	after	after	ADP
dpc-2653	211	7	treatment	treatment	NOUN
dpc-2653	211	8	discontinuation	discontinuation	NOUN
dpc-2653	211	9	[	[	X
dpc-2653	211	10	38	38	NUM
dpc-2653	211	11	]	]	PUNCT
dpc-2653	211	12	.	.	PUNCT
dpc-2653	212	1	lichenoid	lichenoid	NOUN
dpc-2653	212	2	reactions	reaction	NOUN
dpc-2653	212	3	are	be	AUX
dpc-2653	212	4	figure	figure	NOUN
dpc-2653	212	5	3	3	NUM
dpc-2653	212	6	.	.	PUNCT
dpc-2653	213	1	nail	nail	NOUN
dpc-2653	213	2	toxicities	toxicity	NOUN
dpc-2653	213	3	due	due	ADJ
dpc-2653	213	4	to	to	ADP
dpc-2653	213	5	immunotherapy	immunotherapy	NOUN
dpc-2653	213	6	.	.	PUNCT
dpc-2653	214	1	a.	a.	NOUN
dpc-2653	214	2	psoriatic	psoriatic	ADJ
dpc-2653	214	3	changes	change	NOUN
dpc-2653	214	4	in	in	ADP
dpc-2653	214	5	nails	nail	NOUN
dpc-2653	214	6	following	follow	VERB
dpc-2653	214	7	treatment	treatment	NOUN
dpc-2653	214	8	with	with	ADP
dpc-2653	214	9	immune	immune	ADJ
dpc-2653	214	10	checkpoint	checkpoint	NOUN
dpc-2653	214	11	inhibitor	inhibitor	NOUN
dpc-2653	214	12	(	(	PUNCT
dpc-2653	214	13	pembrolizumab	pembrolizumab	NOUN
dpc-2653	214	14	):	):	PUNCT
dpc-2653	214	15	presence	presence	NOUN
dpc-2653	214	16	of	of	ADP
dpc-2653	214	17	subtle	subtle	ADJ
dpc-2653	214	18	pitting	pitting	NOUN
dpc-2653	214	19	,	,	PUNCT
dpc-2653	214	20	onycholysis	onycholysis	NOUN
dpc-2653	214	21	and	and	CCONJ
dpc-2653	214	22	paronychia	paronychia	VERB
dpc-2653	214	23	with	with	ADP
dpc-2653	214	24	scaling	scaling	NOUN
dpc-2653	214	25	of	of	ADP
dpc-2653	214	26	the	the	DET
dpc-2653	214	27	skin	skin	NOUN
dpc-2653	214	28	.	.	PUNCT
dpc-2653	215	1	b.	b.	PROPN
dpc-2653	215	2	same	same	ADJ
dpc-2653	215	3	patient	patient	NOUN
dpc-2653	215	4	as	as	ADP
dpc-2653	215	5	a	a	DET
dpc-2653	215	6	,	,	PUNCT
dpc-2653	215	7	dermoscopic	dermoscopic	ADJ
dpc-2653	215	8	image	image	NOUN
dpc-2653	215	9	:	:	PUNCT
dpc-2653	215	10	remark	remark	VERB
dpc-2653	215	11	the	the	DET
dpc-2653	215	12	presence	presence	NOUN
dpc-2653	215	13	of	of	ADP
dpc-2653	215	14	splinter	splinter	NOUN
dpc-2653	215	15	hemorrhages	hemorrhage	NOUN
dpc-2653	215	16	as	as	ADV
dpc-2653	215	17	well	well	ADV
dpc-2653	215	18	as	as	ADP
dpc-2653	215	19	the	the	DET
dpc-2653	215	20	yellow	yellow	ADJ
dpc-2653	215	21	discoloration	discoloration	NOUN
dpc-2653	215	22	of	of	ADP
dpc-2653	215	23	the	the	DET
dpc-2653	215	24	onycholysis	onycholysis	NOUN
dpc-2653	215	25	suggestive	suggestive	ADJ
dpc-2653	215	26	of	of	ADP
dpc-2653	215	27	psoriatic	psoriatic	ADJ
dpc-2653	215	28	disease	disease	NOUN
dpc-2653	215	29	.	.	PUNCT
dpc-2653	216	1	c	c	X
dpc-2653	216	2	,	,	PUNCT
dpc-2653	216	3	d.	d.	PROPN
dpc-2653	216	4	lichenoid	lichenoid	PROPN
dpc-2653	216	5	-	-	PUNCT
dpc-2653	216	6	like	like	ADJ
dpc-2653	216	7	reactions	reaction	NOUN
dpc-2653	216	8	in	in	ADP
dpc-2653	216	9	a	a	DET
dpc-2653	216	10	melanoma	melanoma	NOUN
dpc-2653	216	11	patient	patient	NOUN
dpc-2653	216	12	treated	treat	VERB
dpc-2653	216	13	with	with	ADP
dpc-2653	216	14	nivolumab	nivolumab	NOUN
dpc-2653	216	15	:	:	PUNCT
dpc-2653	216	16	onychorhexis	onychorhexis	NOUN
dpc-2653	216	17	visualized	visualize	VERB
dpc-2653	216	18	both	both	CCONJ
dpc-2653	216	19	clinically	clinically	ADV
dpc-2653	216	20	and	and	CCONJ
dpc-2653	216	21	with	with	ADP
dpc-2653	216	22	dermoscopy	dermoscopy	NOUN
dpc-2653	216	23	.	.	PUNCT
dpc-2653	217	1	in	in	ADP
dpc-2653	217	2	the	the	DET
dpc-2653	217	3	dermoscopic	dermoscopic	ADJ
dpc-2653	217	4	image	image	NOUN
dpc-2653	217	5	the	the	DET
dpc-2653	217	6	presence	presence	NOUN
dpc-2653	217	7	of	of	ADP
dpc-2653	217	8	dust	dust	NOUN
dpc-2653	217	9	in	in	ADP
dpc-2653	217	10	the	the	DET
dpc-2653	217	11	nail	nail	NOUN
dpc-2653	217	12	fissures	fissure	NOUN
dpc-2653	217	13	gives	give	VERB
dpc-2653	217	14	the	the	DET
dpc-2653	217	15	characteristic	characteristic	ADJ
dpc-2653	217	16	image	image	NOUN
dpc-2653	217	17	of	of	ADP
dpc-2653	217	18	“	"	PUNCT
dpc-2653	217	19	dirty	dirty	ADJ
dpc-2653	217	20	nail	nail	NOUN
dpc-2653	217	21	”	"	PUNCT
dpc-2653	217	22	that	that	PRON
dpc-2653	217	23	is	be	AUX
dpc-2653	217	24	a	a	DET
dpc-2653	217	25	common	common	ADJ
dpc-2653	217	26	finding	finding	NOUN
dpc-2653	217	27	in	in	ADP
dpc-2653	217	28	lichen	lichen	NOUN
dpc-2653	217	29	-	-	PUNCT
dpc-2653	217	30	like	like	ADJ
dpc-2653	217	31	reactions	reaction	NOUN
dpc-2653	217	32	of	of	ADP
dpc-2653	217	33	the	the	DET
dpc-2653	217	34	nail	nail	NOUN
dpc-2653	217	35	plate	plate	NOUN
dpc-2653	217	36	.	.	PUNCT
dpc-2653	218	1	e	e	X
dpc-2653	218	2	,	,	PUNCT
dpc-2653	218	3	f	f	NOUN
dpc-2653	218	4	:	:	PUNCT
dpc-2653	218	5	same	same	ADJ
dpc-2653	218	6	patient	patient	NOUN
dpc-2653	218	7	as	as	ADP
dpc-2653	218	8	c	c	PROPN
dpc-2653	218	9	,	,	PUNCT
dpc-2653	218	10	d	d	X
dpc-2653	218	11	different	different	ADJ
dpc-2653	218	12	nails	nail	NOUN
dpc-2653	218	13	,	,	PUNCT
dpc-2653	218	14	dermoscopic	dermoscopic	NOUN
dpc-2653	218	15	images	image	NOUN
dpc-2653	218	16	.	.	PUNCT
dpc-2653	219	1	characteristic	characteristic	ADJ
dpc-2653	219	2	presence	presence	NOUN
dpc-2653	219	3	of	of	ADP
dpc-2653	219	4	erythema	erythema	NOUN
dpc-2653	219	5	in	in	ADP
dpc-2653	219	6	the	the	DET
dpc-2653	219	7	lunula	lunula	NOUN
dpc-2653	219	8	seen	see	VERB
dpc-2653	219	9	in	in	ADP
dpc-2653	219	10	patients	patient	NOUN
dpc-2653	219	11	treated	treat	VERB
dpc-2653	219	12	with	with	ADP
dpc-2653	219	13	nivolumab	nivolumab	NOUN
dpc-2653	219	14	.	.	PUNCT
dpc-2653	220	1	10	10	NUM
dpc-2653	220	2	review	review	NOUN
dpc-2653	220	3	|	|	ADV
dpc-2653	220	4	dermatol	dermatol	ADJ
dpc-2653	220	5	pract	pract	NOUN
dpc-2653	220	6	concept	concept	NOUN
dpc-2653	220	7	.	.	PUNCT
dpc-2653	221	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	221	2	first	first	ADJ
dpc-2653	221	3	-	-	PUNCT
dpc-2653	221	4	line	line	NOUN
dpc-2653	221	5	treatment	treatment	NOUN
dpc-2653	221	6	for	for	ADP
dpc-2653	221	7	these	these	DET
dpc-2653	221	8	nail	nail	NOUN
dpc-2653	221	9	changes	change	NOUN
dpc-2653	221	10	is	be	AUX
dpc-2653	221	11	topical	topical	ADJ
dpc-2653	221	12	therapy	therapy	NOUN
dpc-2653	221	13	.	.	PUNCT
dpc-2653	222	1	if	if	SCONJ
dpc-2653	222	2	topicals	topical	NOUN
dpc-2653	222	3	fail	fail	VERB
dpc-2653	222	4	and	and	CCONJ
dpc-2653	222	5	there	there	PRON
dpc-2653	222	6	is	be	VERB
dpc-2653	222	7	also	also	ADV
dpc-2653	222	8	skin	skin	NOUN
dpc-2653	222	9	involvement	involvement	NOUN
dpc-2653	222	10	,	,	PUNCT
dpc-2653	222	11	systemic	systemic	ADJ
dpc-2653	222	12	therapy	therapy	NOUN
dpc-2653	222	13	should	should	AUX
dpc-2653	222	14	be	be	AUX
dpc-2653	222	15	considered	consider	VERB
dpc-2653	222	16	[	[	X
dpc-2653	222	17	43	43	NUM
dpc-2653	222	18	,	,	PUNCT
dpc-2653	222	19	45	45	NUM
dpc-2653	222	20	]	]	PUNCT
dpc-2653	222	21	.	.	PUNCT
dpc-2653	223	1	pathogenesis	pathogenesis	NOUN
dpc-2653	223	2	of	of	ADP
dpc-2653	223	3	certain	certain	ADJ
dpc-2653	223	4	nail	nail	NOUN
dpc-2653	223	5	changes	change	NOUN
dpc-2653	223	6	and	and	CCONJ
dpc-2653	223	7	potentially	potentially	ADV
dpc-2653	223	8	responsible	responsible	ADJ
dpc-2653	223	9	anticancer	anticancer	NOUN
dpc-2653	223	10	drugs	drug	NOUN
dpc-2653	223	11	.	.	PUNCT
dpc-2653	224	1	table	table	NOUN
dpc-2653	224	2	4	4	NUM
dpc-2653	224	3	highlights	highlight	NOUN
dpc-2653	224	4	the	the	DET
dpc-2653	224	5	diagnostic	diagnostic	ADJ
dpc-2653	224	6	challenges	challenge	NOUN
dpc-2653	224	7	related	relate	VERB
dpc-2653	224	8	to	to	ADP
dpc-2653	224	9	drug	drug	NOUN
dpc-2653	224	10	-	-	PUNCT
dpc-2653	224	11	induced	induce	VERB
dpc-2653	224	12	nail	nail	NOUN
dpc-2653	224	13	toxicities	toxicity	NOUN
dpc-2653	224	14	.	.	PUNCT
dpc-2653	225	1	melanonychia	melanonychia	PROPN
dpc-2653	225	2	melanonychia	melanonychia	NOUN
dpc-2653	225	3	represents	represent	VERB
dpc-2653	225	4	one	one	NUM
dpc-2653	225	5	of	of	ADP
dpc-2653	225	6	the	the	DET
dpc-2653	225	7	most	most	ADV
dpc-2653	225	8	common	common	ADJ
dpc-2653	225	9	adverse	adverse	ADJ
dpc-2653	225	10	effects	effect	NOUN
dpc-2653	225	11	of	of	ADP
dpc-2653	225	12	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	225	13	agents	agent	NOUN
dpc-2653	225	14	.	.	PUNCT
dpc-2653	226	1	saraswat	saraswat	VERB
dpc-2653	226	2	et	et	PROPN
dpc-2653	226	3	al	al	PROPN
dpc-2653	226	4	.	.	PUNCT
dpc-2653	227	1	[	[	X
dpc-2653	227	2	4	4	X
dpc-2653	227	3	]	]	PUNCT
dpc-2653	227	4	and	and	CCONJ
dpc-2653	227	5	pavey	pavey	NOUN
dpc-2653	227	6	et	et	PROPN
dpc-2653	227	7	al	al	PROPN
dpc-2653	227	8	.	.	PUNCT
dpc-2653	228	1	[	[	X
dpc-2653	228	2	1	1	X
dpc-2653	228	3	]	]	PUNCT
dpc-2653	228	4	found	find	VERB
dpc-2653	228	5	nail	nail	NOUN
dpc-2653	228	6	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	228	7	as	as	ADP
dpc-2653	228	8	the	the	DET
dpc-2653	228	9	most	most	ADV
dpc-2653	228	10	common	common	ADJ
dpc-2653	228	11	nail	nail	NOUN
dpc-2653	228	12	toxicity	toxicity	NOUN
dpc-2653	228	13	of	of	ADP
dpc-2653	228	14	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	228	15	drugs	drug	NOUN
dpc-2653	228	16	.	.	PUNCT
dpc-2653	229	1	this	this	DET
dpc-2653	229	2	pigmentation	pigmentation	NOUN
dpc-2653	229	3	develops	develop	VERB
dpc-2653	229	4	after	after	ADP
dpc-2653	229	5	1–2	1–2	NUM
dpc-2653	229	6	months	month	NOUN
dpc-2653	229	7	of	of	ADP
dpc-2653	229	8	treatment	treatment	NOUN
dpc-2653	229	9	and	and	CCONJ
dpc-2653	229	10	is	be	AUX
dpc-2653	229	11	proposed	propose	VERB
dpc-2653	229	12	to	to	PART
dpc-2653	229	13	be	be	AUX
dpc-2653	229	14	the	the	DET
dpc-2653	229	15	outcome	outcome	NOUN
dpc-2653	229	16	of	of	ADP
dpc-2653	229	17	matrix	matrix	NOUN
dpc-2653	229	18	melanocyte	melanocyte	NOUN
dpc-2653	229	19	activation	activation	NOUN
dpc-2653	229	20	,	,	PUNCT
dpc-2653	229	21	which	which	PRON
dpc-2653	229	22	usually	usually	ADV
dpc-2653	229	23	affects	affect	VERB
dpc-2653	229	24	several	several	ADJ
dpc-2653	229	25	nail	nail	NOUN
dpc-2653	229	26	plates	plate	NOUN
dpc-2653	229	27	.	.	PUNCT
dpc-2653	230	1	nail	nail	NOUN
dpc-2653	230	2	melanocytes	melanocyte	NOUN
dpc-2653	230	3	are	be	AUX
dpc-2653	230	4	quiescent	quiescent	ADJ
dpc-2653	230	5	and	and	CCONJ
dpc-2653	230	6	generally	generally	ADV
dpc-2653	230	7	do	do	AUX
dpc-2653	230	8	not	not	PART
dpc-2653	230	9	produce	produce	VERB
dpc-2653	230	10	melanin	melanin	NOUN
dpc-2653	230	11	.	.	PUNCT
dpc-2653	231	1	melanonychia	melanonychia	PROPN
dpc-2653	231	2	results	result	NOUN
dpc-2653	231	3	from	from	ADP
dpc-2653	231	4	the	the	DET
dpc-2653	231	5	direct	direct	ADJ
dpc-2653	231	6	toxic	toxic	ADJ
dpc-2653	231	7	action	action	NOUN
dpc-2653	231	8	of	of	ADP
dpc-2653	231	9	chemotherapy	chemotherapy	NOUN
dpc-2653	231	10	on	on	ADP
dpc-2653	231	11	the	the	DET
dpc-2653	231	12	melanocytes	melanocyte	NOUN
dpc-2653	231	13	of	of	ADP
dpc-2653	231	14	the	the	DET
dpc-2653	231	15	nail	nail	NOUN
dpc-2653	231	16	matrix	matrix	NOUN
dpc-2653	231	17	,	,	PUNCT
dpc-2653	231	18	with	with	ADP
dpc-2653	231	19	secondary	secondary	ADJ
dpc-2653	231	20	melanin	melanin	NOUN
dpc-2653	231	21	production	production	NOUN
dpc-2653	231	22	analogous	analogous	ADJ
dpc-2653	231	23	to	to	ADP
dpc-2653	231	24	that	that	PRON
dpc-2653	231	25	of	of	ADP
dpc-2653	231	26	post	post	ADJ
dpc-2653	231	27	-	-	ADJ
dpc-2653	231	28	inflammatory	inflammatory	ADJ
dpc-2653	231	29	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	231	30	seen	see	VERB
dpc-2653	231	31	in	in	ADP
dpc-2653	231	32	the	the	DET
dpc-2653	231	33	skin	skin	NOUN
dpc-2653	231	34	[	[	X
dpc-2653	231	35	4649	4649	NUM
dpc-2653	231	36	]	]	PUNCT
dpc-2653	231	37	.	.	PUNCT
dpc-2653	232	1	the	the	DET
dpc-2653	232	2	activation	activation	NOUN
dpc-2653	232	3	of	of	ADP
dpc-2653	232	4	a	a	DET
dpc-2653	232	5	subgroup	subgroup	NOUN
dpc-2653	232	6	of	of	ADP
dpc-2653	232	7	melanocytes	melanocyte	NOUN
dpc-2653	232	8	produces	produce	VERB
dpc-2653	232	9	a	a	DET
dpc-2653	232	10	single	single	ADJ
dpc-2653	232	11	or	or	CCONJ
dpc-2653	232	12	several	several	ADJ
dpc-2653	232	13	longitudinal	longitudinal	ADJ
dpc-2653	232	14	pigmented	pigmented	ADJ
dpc-2653	232	15	bands	band	NOUN
dpc-2653	232	16	(	(	PUNCT
dpc-2653	232	17	melanonychia	melanonychia	VERB
dpc-2653	232	18	striata	striata	NOUN
dpc-2653	232	19	)	)	PUNCT
dpc-2653	232	20	whereas	whereas	SCONJ
dpc-2653	232	21	diffuse	diffuse	VERB
dpc-2653	232	22	activation	activation	NOUN
dpc-2653	232	23	of	of	ADP
dpc-2653	232	24	melanocytes	melanocyte	NOUN
dpc-2653	232	25	gives	give	VERB
dpc-2653	232	26	rise	rise	NOUN
dpc-2653	232	27	to	to	PART
dpc-2653	232	28	diffuse	diffuse	VERB
dpc-2653	232	29	nail	nail	NOUN
dpc-2653	232	30	pigmentation	pigmentation	NOUN
dpc-2653	232	31	(	(	PUNCT
dpc-2653	232	32	total	total	ADJ
dpc-2653	232	33	melanonychia	melanonychia	NOUN
dpc-2653	232	34	)	)	PUNCT
dpc-2653	232	35	.	.	PUNCT
dpc-2653	233	1	transverse	transverse	PROPN
dpc-2653	233	2	melanonychia	melanonychia	PROPN
dpc-2653	233	3	may	may	AUX
dpc-2653	233	4	also	also	ADV
dpc-2653	233	5	be	be	AUX
dpc-2653	233	6	observed	observe	VERB
dpc-2653	233	7	[	[	PUNCT
dpc-2653	233	8	2	2	NUM
dpc-2653	233	9	]	]	PUNCT
dpc-2653	233	10	.	.	PUNCT
dpc-2653	234	1	skin	skin	NOUN
dpc-2653	234	2	or	or	CCONJ
dpc-2653	234	3	mucosal	mucosal	NOUN
dpc-2653	234	4	pigmentary	pigmentary	NOUN
dpc-2653	234	5	changes	change	NOUN
dpc-2653	234	6	are	be	AUX
dpc-2653	234	7	frequently	frequently	ADV
dpc-2653	234	8	associated	associate	VERB
dpc-2653	234	9	.	.	PUNCT
dpc-2653	235	1	nail	nail	NOUN
dpc-2653	235	2	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	235	3	is	be	AUX
dpc-2653	235	4	more	more	ADV
dpc-2653	235	5	often	often	ADV
dpc-2653	235	6	reported	report	VERB
dpc-2653	235	7	with	with	ADP
dpc-2653	235	8	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	235	9	agents	agent	NOUN
dpc-2653	235	10	like	like	ADP
dpc-2653	235	11	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	235	12	,	,	PUNCT
dpc-2653	235	13	cisplatin	cisplatin	NOUN
dpc-2653	235	14	,	,	PUNCT
dpc-2653	235	15	fluorouracil	fluorouracil	NOUN
dpc-2653	235	16	and	and	CCONJ
dpc-2653	235	17	its	its	PRON
dpc-2653	235	18	prodrug	prodrug	NOUN
dpc-2653	235	19	capecitabine	capecitabine	NOUN
dpc-2653	235	20	,	,	PUNCT
dpc-2653	235	21	taxanes	taxane	NOUN
dpc-2653	235	22	,	,	PUNCT
dpc-2653	235	23	doxorubicin	doxorubicin	PROPN
dpc-2653	235	24	,	,	PUNCT
dpc-2653	235	25	bleomycin	bleomycin	PROPN
dpc-2653	235	26	and	and	CCONJ
dpc-2653	235	27	imatinib	imatinib	NOUN
dpc-2653	235	28	[	[	X
dpc-2653	235	29	16	16	NUM
dpc-2653	235	30	,	,	PUNCT
dpc-2653	235	31	38	38	NUM
dpc-2653	235	32	,	,	PUNCT
dpc-2653	235	33	5054	5054	NUM
dpc-2653	235	34	]	]	PUNCT
dpc-2653	235	35	(	(	PUNCT
dpc-2653	235	36	table	table	NOUN
dpc-2653	235	37	5	5	NUM
dpc-2653	235	38	)	)	PUNCT
dpc-2653	235	39	.	.	PUNCT
dpc-2653	236	1	chemo	chemo	NOUN
dpc-2653	236	2	-	-	PUNCT
dpc-2653	236	3	induced	induce	VERB
dpc-2653	236	4	hyperpigmentation	hyperpigmentation	NOUN
dpc-2653	236	5	does	do	AUX
dpc-2653	236	6	not	not	PART
dpc-2653	236	7	require	require	VERB
dpc-2653	236	8	any	any	DET
dpc-2653	236	9	treatment	treatment	NOUN
dpc-2653	236	10	and	and	CCONJ
dpc-2653	236	11	progressively	progressively	ADV
dpc-2653	236	12	regresses	regress	VERB
dpc-2653	236	13	several	several	ADJ
dpc-2653	236	14	months	month	NOUN
dpc-2653	236	15	after	after	ADP
dpc-2653	236	16	treatment	treatment	NOUN
dpc-2653	236	17	discontinuation	discontinuation	NOUN
dpc-2653	236	18	.	.	PUNCT
dpc-2653	237	1	for	for	ADP
dpc-2653	237	2	patients	patient	NOUN
dpc-2653	237	3	who	who	PRON
dpc-2653	237	4	would	would	AUX
dpc-2653	237	5	like	like	VERB
dpc-2653	237	6	to	to	PART
dpc-2653	237	7	conceal	conceal	VERB
dpc-2653	237	8	this	this	DET
dpc-2653	237	9	melanonychia	melanonychia	NOUN
dpc-2653	237	10	,	,	PUNCT
dpc-2653	237	11	dark	dark	ADJ
dpc-2653	237	12	-	-	PUNCT
dpc-2653	237	13	colored	color	VERB
dpc-2653	237	14	nail	nail	NOUN
dpc-2653	237	15	polish	polish	NOUN
dpc-2653	237	16	may	may	AUX
dpc-2653	237	17	be	be	AUX
dpc-2653	237	18	proposed	propose	VERB
dpc-2653	237	19	.	.	PUNCT
dpc-2653	238	1	beau	beau	PROPN
dpc-2653	238	2	’s	’s	PART
dpc-2653	238	3	lines	line	NOUN
dpc-2653	238	4	beau	beau	PROPN
dpc-2653	238	5	’s	’s	PART
dpc-2653	238	6	lines	line	NOUN
dpc-2653	238	7	correspond	correspond	VERB
dpc-2653	238	8	to	to	ADP
dpc-2653	238	9	the	the	DET
dpc-2653	238	10	formation	formation	NOUN
dpc-2653	238	11	of	of	ADP
dpc-2653	238	12	transverse	transverse	ADJ
dpc-2653	238	13	linear	linear	ADJ
dpc-2653	238	14	depressions	depression	NOUN
dpc-2653	238	15	in	in	ADP
dpc-2653	238	16	the	the	DET
dpc-2653	238	17	dorsum	dorsum	NOUN
dpc-2653	238	18	of	of	ADP
dpc-2653	238	19	the	the	DET
dpc-2653	238	20	nail	nail	NOUN
dpc-2653	238	21	plate	plate	NOUN
dpc-2653	238	22	and	and	CCONJ
dpc-2653	238	23	result	result	VERB
dpc-2653	238	24	from	from	ADP
dpc-2653	238	25	a	a	DET
dpc-2653	238	26	transitory	transitory	ADJ
dpc-2653	238	27	decrease	decrease	NOUN
dpc-2653	238	28	in	in	ADP
dpc-2653	238	29	mitotic	mitotic	ADJ
dpc-2653	238	30	activity	activity	NOUN
dpc-2653	238	31	of	of	ADP
dpc-2653	238	32	the	the	DET
dpc-2653	238	33	proximal	proximal	ADJ
dpc-2653	238	34	nail	nail	NOUN
dpc-2653	238	35	matrix	matrix	NOUN
dpc-2653	238	36	keratinocytes	keratinocyte	NOUN
dpc-2653	238	37	.	.	PUNCT
dpc-2653	239	1	the	the	DET
dpc-2653	239	2	depth	depth	NOUN
dpc-2653	239	3	of	of	ADP
dpc-2653	239	4	the	the	DET
dpc-2653	239	5	groove	groove	NOUN
dpc-2653	239	6	is	be	AUX
dpc-2653	239	7	strictly	strictly	ADV
dpc-2653	239	8	immune	immune	ADJ
dpc-2653	239	9	checkpoints	checkpoint	NOUN
dpc-2653	239	10	include	include	VERB
dpc-2653	239	11	cytotoxic	cytotoxic	ADJ
dpc-2653	239	12	t	t	PROPN
dpc-2653	239	13	-	-	PUNCT
dpc-2653	239	14	lymphocyte	lymphocyte	NOUN
dpc-2653	239	15	antigen	antigen	NOUN
dpc-2653	239	16	4	4	NUM
dpc-2653	239	17	(	(	PUNCT
dpc-2653	239	18	ctla-4	ctla-4	NOUN
dpc-2653	239	19	)	)	PUNCT
dpc-2653	239	20	,	,	PUNCT
dpc-2653	239	21	programmed	program	VERB
dpc-2653	239	22	cell	cell	NOUN
dpc-2653	239	23	death	death	NOUN
dpc-2653	239	24	1	1	NUM
dpc-2653	239	25	(	(	PUNCT
dpc-2653	239	26	pd-1	pd-1	ADV
dpc-2653	239	27	)	)	PUNCT
dpc-2653	239	28	and	and	CCONJ
dpc-2653	239	29	programmed	program	VERB
dpc-2653	239	30	cell	cell	NOUN
dpc-2653	239	31	death	death	NOUN
dpc-2653	239	32	ligand	ligand	NOUN
dpc-2653	239	33	1	1	NUM
dpc-2653	239	34	(	(	PUNCT
dpc-2653	239	35	pd	pd	NOUN
dpc-2653	239	36	-	-	PUNCT
dpc-2653	239	37	l1	l1	PROPN
dpc-2653	239	38	)	)	PUNCT
dpc-2653	239	39	.	.	PUNCT
dpc-2653	240	1	the	the	DET
dpc-2653	240	2	ctla-4	ctla-4	NOUN
dpc-2653	240	3	,	,	PUNCT
dpc-2653	240	4	pd-1	pd-1	ADV
dpc-2653	240	5	,	,	PUNCT
dpc-2653	240	6	and	and	CCONJ
dpc-2653	240	7	pd	pd	PROPN
dpc-2653	240	8	-	-	PROPN
dpc-2653	240	9	l1	l1	PROPN
dpc-2653	240	10	pathways	pathway	NOUN
dpc-2653	240	11	mediate	mediate	VERB
dpc-2653	240	12	immune	immune	ADJ
dpc-2653	240	13	responses	response	NOUN
dpc-2653	240	14	at	at	ADP
dpc-2653	240	15	different	different	ADJ
dpc-2653	240	16	levels	level	NOUN
dpc-2653	240	17	.	.	PUNCT
dpc-2653	241	1	ctla-4	ctla-4	NOUN
dpc-2653	241	2	controls	control	VERB
dpc-2653	241	3	the	the	DET
dpc-2653	241	4	amplitude	amplitude	NOUN
dpc-2653	241	5	of	of	ADP
dpc-2653	241	6	immunologic	immunologic	ADJ
dpc-2653	241	7	response	response	NOUN
dpc-2653	241	8	at	at	ADP
dpc-2653	241	9	early	early	ADJ
dpc-2653	241	10	stages	stage	NOUN
dpc-2653	241	11	of	of	ADP
dpc-2653	241	12	t	t	NOUN
dpc-2653	241	13	-	-	PUNCT
dpc-2653	241	14	cell	cell	NOUN
dpc-2653	241	15	activation	activation	NOUN
dpc-2653	241	16	,	,	PUNCT
dpc-2653	241	17	whereas	whereas	SCONJ
dpc-2653	241	18	pd-1	pd-1	ADV
dpc-2653	241	19	and	and	CCONJ
dpc-2653	241	20	pd	pd	PROPN
dpc-2653	241	21	-	-	PROPN
dpc-2653	241	22	l1	l1	PROPN
dpc-2653	241	23	pathways	pathway	NOUN
dpc-2653	241	24	act	act	VERB
dpc-2653	241	25	at	at	ADP
dpc-2653	241	26	later	later	ADJ
dpc-2653	241	27	stages	stage	NOUN
dpc-2653	241	28	,	,	PUNCT
dpc-2653	241	29	limiting	limit	VERB
dpc-2653	241	30	tcell	tcell	NOUN
dpc-2653	241	31	activity	activity	NOUN
dpc-2653	241	32	in	in	ADP
dpc-2653	241	33	the	the	DET
dpc-2653	241	34	peripheral	peripheral	ADJ
dpc-2653	241	35	tissues	tissue	NOUN
dpc-2653	241	36	.	.	PUNCT
dpc-2653	242	1	by	by	ADP
dpc-2653	242	2	activating	activate	VERB
dpc-2653	242	3	cytotoxic	cytotoxic	ADJ
dpc-2653	242	4	cd4+/cd8	cd4+/cd8	NOUN
dpc-2653	242	5	+	+	CCONJ
dpc-2653	242	6	t	t	NOUN
dpc-2653	242	7	cells	cell	NOUN
dpc-2653	242	8	,	,	PUNCT
dpc-2653	242	9	immune	immune	ADJ
dpc-2653	242	10	checkpoint	checkpoint	NOUN
dpc-2653	242	11	blockade	blockade	NOUN
dpc-2653	242	12	therapy	therapy	NOUN
dpc-2653	242	13	shifts	shift	NOUN
dpc-2653	242	14	the	the	DET
dpc-2653	242	15	immune	immune	ADJ
dpc-2653	242	16	system	system	NOUN
dpc-2653	242	17	towards	towards	ADP
dpc-2653	242	18	anti	anti	ADJ
dpc-2653	242	19	-	-	ADJ
dpc-2653	242	20	tumor	tumor	ADJ
dpc-2653	242	21	activity	activity	NOUN
dpc-2653	242	22	[	[	X
dpc-2653	242	23	4244	4244	NUM
dpc-2653	242	24	]	]	PUNCT
dpc-2653	242	25	.	.	PUNCT
dpc-2653	243	1	the	the	DET
dpc-2653	243	2	etiopathogenetic	etiopathogenetic	ADJ
dpc-2653	243	3	mechanism	mechanism	NOUN
dpc-2653	243	4	seems	seem	VERB
dpc-2653	243	5	to	to	PART
dpc-2653	243	6	be	be	AUX
dpc-2653	243	7	connected	connect	VERB
dpc-2653	243	8	to	to	ADP
dpc-2653	243	9	the	the	DET
dpc-2653	243	10	t	t	NOUN
dpc-2653	243	11	-	-	PUNCT
dpc-2653	243	12	cell	cell	NOUN
dpc-2653	243	13	activation	activation	NOUN
dpc-2653	243	14	,	,	PUNCT
dpc-2653	243	15	mediated	mediate	VERB
dpc-2653	243	16	by	by	ADP
dpc-2653	243	17	the	the	DET
dpc-2653	243	18	blockade	blockade	NOUN
dpc-2653	243	19	of	of	ADP
dpc-2653	243	20	pd-1	pd-1	ADP
dpc-2653	243	21	/	/	SYM
dpc-2653	243	22	pd	pd	NOUN
dpc-2653	243	23	-	-	PROPN
dpc-2653	243	24	l1	l1	PROPN
dpc-2653	243	25	and	and	CCONJ
dpc-2653	243	26	ctla-4	ctla-4	NOUN
dpc-2653	243	27	receptors	receptor	NOUN
dpc-2653	243	28	.	.	PUNCT
dpc-2653	244	1	cpis	cpis	PROPN
dpc-2653	244	2	include	include	VERB
dpc-2653	244	3	anti	anti	ADJ
dpc-2653	244	4	-	-	ADJ
dpc-2653	244	5	pd-1	pd-1	ADJ
dpc-2653	244	6	(	(	PUNCT
dpc-2653	244	7	nivolumab	nivolumab	NOUN
dpc-2653	244	8	and	and	CCONJ
dpc-2653	244	9	pembrolizumab	pembrolizumab	NOUN
dpc-2653	244	10	)	)	PUNCT
dpc-2653	244	11	and	and	CCONJ
dpc-2653	244	12	anti	anti	ADJ
dpc-2653	244	13	-	-	ADJ
dpc-2653	244	14	ctla-4	ctla-4	ADJ
dpc-2653	244	15	(	(	PUNCT
dpc-2653	244	16	ipilimumab	ipilimumab	ADJ
dpc-2653	244	17	,	,	PUNCT
dpc-2653	244	18	tremelimumab	tremelimumab	NOUN
dpc-2653	244	19	)	)	PUNCT
dpc-2653	244	20	agents	agent	NOUN
dpc-2653	244	21	,	,	PUNCT
dpc-2653	244	22	as	as	ADV
dpc-2653	244	23	well	well	ADV
dpc-2653	244	24	as	as	ADP
dpc-2653	244	25	the	the	DET
dpc-2653	244	26	newly	newly	ADV
dpc-2653	244	27	developed	develop	VERB
dpc-2653	244	28	anti	anti	ADJ
dpc-2653	244	29	-	-	ADJ
dpc-2653	244	30	pd	pd	ADJ
dpc-2653	244	31	-	-	PUNCT
dpc-2653	244	32	l1	l1	PROPN
dpc-2653	244	33	agents	agent	NOUN
dpc-2653	244	34	(	(	PUNCT
dpc-2653	244	35	atezolizumab	atezolizumab	PROPN
dpc-2653	244	36	,	,	PUNCT
dpc-2653	244	37	durvalumab	durvalumab	PROPN
dpc-2653	244	38	,	,	PUNCT
dpc-2653	244	39	avelumab	avelumab	NOUN
dpc-2653	244	40	)	)	PUNCT
dpc-2653	245	1	[	[	X
dpc-2653	245	2	4244	4244	NUM
dpc-2653	245	3	]	]	PUNCT
dpc-2653	245	4	.	.	PUNCT
dpc-2653	246	1	icis	icis	PROPN
dpc-2653	246	2	nail	nail	PROPN
dpc-2653	246	3	alterations	alteration	NOUN
dpc-2653	246	4	have	have	AUX
dpc-2653	246	5	not	not	PART
dpc-2653	246	6	been	be	AUX
dpc-2653	246	7	systemically	systemically	ADV
dpc-2653	246	8	investigated	investigate	VERB
dpc-2653	246	9	and	and	CCONJ
dpc-2653	246	10	are	be	AUX
dpc-2653	246	11	considered	consider	VERB
dpc-2653	246	12	uncommon	uncommon	ADJ
dpc-2653	246	13	.	.	PUNCT
dpc-2653	247	1	nail	nail	NOUN
dpc-2653	247	2	toxicity	toxicity	NOUN
dpc-2653	247	3	presents	present	NOUN
dpc-2653	247	4	late	late	ADV
dpc-2653	247	5	in	in	ADP
dpc-2653	247	6	time	time	NOUN
dpc-2653	247	7	,	,	PUNCT
dpc-2653	247	8	with	with	ADP
dpc-2653	247	9	an	an	DET
dpc-2653	247	10	onset	onset	NOUN
dpc-2653	247	11	extended	extend	VERB
dpc-2653	247	12	up	up	ADP
dpc-2653	247	13	to	to	ADP
dpc-2653	247	14	several	several	ADJ
dpc-2653	247	15	months	month	NOUN
dpc-2653	247	16	from	from	ADP
dpc-2653	247	17	ici	ici	PROPN
dpc-2653	247	18	initiation	initiation	NOUN
dpc-2653	248	1	[	[	X
dpc-2653	248	2	42	42	NUM
dpc-2653	248	3	,	,	PUNCT
dpc-2653	248	4	43	43	NUM
dpc-2653	248	5	]	]	PUNCT
dpc-2653	248	6	.	.	PUNCT
dpc-2653	249	1	persistence	persistence	NOUN
dpc-2653	249	2	of	of	ADP
dpc-2653	249	3	the	the	DET
dpc-2653	249	4	nail	nail	NOUN
dpc-2653	249	5	change	change	NOUN
dpc-2653	249	6	after	after	ADP
dpc-2653	249	7	ici	ici	PROPN
dpc-2653	249	8	discontinuation	discontinuation	NOUN
dpc-2653	249	9	has	have	AUX
dpc-2653	249	10	been	be	AUX
dpc-2653	249	11	also	also	ADV
dpc-2653	249	12	reported	report	VERB
dpc-2653	249	13	.	.	PUNCT
dpc-2653	250	1	diverse	diverse	ADJ
dpc-2653	250	2	nail	nail	NOUN
dpc-2653	250	3	changes	change	NOUN
dpc-2653	250	4	have	have	AUX
dpc-2653	250	5	been	be	AUX
dpc-2653	250	6	reported	report	VERB
dpc-2653	250	7	in	in	ADP
dpc-2653	250	8	relationship	relationship	NOUN
dpc-2653	250	9	to	to	ADP
dpc-2653	250	10	icis	icis	PROPN
dpc-2653	250	11	,	,	PUNCT
dpc-2653	250	12	including	include	VERB
dpc-2653	250	13	onycholysis	onycholysis	NOUN
dpc-2653	250	14	,	,	PUNCT
dpc-2653	250	15	onychomadesis	onychomadesis	NOUN
dpc-2653	250	16	,	,	PUNCT
dpc-2653	250	17	longitudinal	longitudinal	ADJ
dpc-2653	250	18	fissures	fissure	NOUN
dpc-2653	250	19	,	,	PUNCT
dpc-2653	250	20	onychorrhexis	onychorrhexis	ADV
dpc-2653	250	21	,	,	PUNCT
dpc-2653	250	22	layered	layered	ADJ
dpc-2653	250	23	splitting	splitting	NOUN
dpc-2653	250	24	of	of	ADP
dpc-2653	250	25	the	the	DET
dpc-2653	250	26	nail	nail	NOUN
dpc-2653	250	27	plate	plate	NOUN
dpc-2653	250	28	,	,	PUNCT
dpc-2653	250	29	lunular	lunular	ADV
dpc-2653	250	30	erythema	erythema	ADV
dpc-2653	250	31	,	,	PUNCT
dpc-2653	250	32	thinning	thinning	NOUN
dpc-2653	250	33	of	of	ADP
dpc-2653	250	34	the	the	DET
dpc-2653	250	35	nail	nail	NOUN
dpc-2653	250	36	plate	plate	NOUN
dpc-2653	250	37	and	and	CCONJ
dpc-2653	250	38	fragility	fragility	NOUN
dpc-2653	250	39	.	.	PUNCT
dpc-2653	251	1	commonly	commonly	ADV
dpc-2653	251	2	,	,	PUNCT
dpc-2653	251	3	more	more	ADJ
dpc-2653	251	4	than	than	ADP
dpc-2653	251	5	one	one	NUM
dpc-2653	251	6	fingeror	fingeror	NOUN
dpc-2653	251	7	toenails	toenail	NOUN
dpc-2653	251	8	are	be	AUX
dpc-2653	251	9	involved	involve	VERB
dpc-2653	251	10	.	.	PUNCT
dpc-2653	252	1	nail	nail	NOUN
dpc-2653	252	2	psoriasis	psoriasis	NOUN
dpc-2653	252	3	is	be	AUX
dpc-2653	252	4	the	the	DET
dpc-2653	252	5	most	most	ADV
dpc-2653	252	6	common	common	ADJ
dpc-2653	252	7	immunotherapy	immunotherapy	NOUN
dpc-2653	252	8	-	-	PUNCT
dpc-2653	252	9	related	relate	VERB
dpc-2653	252	10	toxicity	toxicity	NOUN
dpc-2653	252	11	[	[	X
dpc-2653	252	12	42	42	NUM
dpc-2653	252	13	,	,	PUNCT
dpc-2653	252	14	45	45	NUM
dpc-2653	252	15	]	]	PUNCT
dpc-2653	252	16	.	.	PUNCT
dpc-2653	253	1	since	since	SCONJ
dpc-2653	253	2	the	the	DET
dpc-2653	253	3	majority	majority	NOUN
dpc-2653	253	4	of	of	ADP
dpc-2653	253	5	nail	nail	NOUN
dpc-2653	253	6	alterations	alteration	NOUN
dpc-2653	253	7	appear	appear	VERB
dpc-2653	253	8	in	in	ADP
dpc-2653	253	9	conjunction	conjunction	NOUN
dpc-2653	253	10	with	with	ADP
dpc-2653	253	11	psoriasiform	psoriasiform	NOUN
dpc-2653	253	12	or	or	CCONJ
dpc-2653	253	13	lichenoid	lichenoid	NOUN
dpc-2653	253	14	rashes	rash	NOUN
dpc-2653	253	15	,	,	PUNCT
dpc-2653	253	16	they	they	PRON
dpc-2653	253	17	are	be	AUX
dpc-2653	253	18	most	most	ADV
dpc-2653	253	19	probably	probably	ADV
dpc-2653	253	20	of	of	ADP
dpc-2653	253	21	the	the	DET
dpc-2653	253	22	same	same	ADJ
dpc-2653	253	23	nature	nature	NOUN
dpc-2653	253	24	.	.	PUNCT
dpc-2653	254	1	in	in	ADP
dpc-2653	254	2	line	line	NOUN
dpc-2653	254	3	with	with	ADP
dpc-2653	254	4	this	this	DET
dpc-2653	254	5	theory	theory	NOUN
dpc-2653	254	6	are	be	AUX
dpc-2653	254	7	the	the	DET
dpc-2653	254	8	histopathologic	histopathologic	PROPN
dpc-2653	254	9	alterations	alteration	NOUN
dpc-2653	254	10	found	find	VERB
dpc-2653	254	11	in	in	ADP
dpc-2653	254	12	two	two	NUM
dpc-2653	254	13	patients	patient	NOUN
dpc-2653	254	14	exhibiting	exhibit	VERB
dpc-2653	254	15	onycholysis	onycholysis	NOUN
dpc-2653	254	16	that	that	PRON
dpc-2653	254	17	were	be	AUX
dpc-2653	254	18	consistent	consistent	ADJ
dpc-2653	254	19	with	with	ADP
dpc-2653	254	20	lichenoid	lichenoid	PROPN
dpc-2653	254	21	reaction	reaction	NOUN
dpc-2653	254	22	.	.	PUNCT
dpc-2653	255	1	this	this	PRON
dpc-2653	255	2	develops	develop	VERB
dpc-2653	255	3	either	either	CCONJ
dpc-2653	255	4	as	as	ADP
dpc-2653	255	5	a	a	DET
dpc-2653	255	6	deterioration	deterioration	NOUN
dpc-2653	255	7	of	of	ADP
dpc-2653	255	8	pre	pre	ADJ
dpc-2653	255	9	-	-	ADJ
dpc-2653	255	10	existing	exist	VERB
dpc-2653	255	11	nail	nail	NOUN
dpc-2653	255	12	psoriasis	psoriasis	NOUN
dpc-2653	255	13	,	,	PUNCT
dpc-2653	255	14	or	or	CCONJ
dpc-2653	255	15	as	as	ADP
dpc-2653	255	16	a	a	DET
dpc-2653	255	17	de	de	ADJ
dpc-2653	255	18	-	-	ADJ
dpc-2653	255	19	novo	novo	ADJ
dpc-2653	255	20	appearance	appearance	NOUN
dpc-2653	255	21	.	.	PUNCT
dpc-2653	256	1	histopathologically	histopathologically	ADV
dpc-2653	256	2	confirmed	confirm	VERB
dpc-2653	256	3	psoriasis	psoriasis	NOUN
dpc-2653	256	4	of	of	ADP
dpc-2653	256	5	the	the	DET
dpc-2653	256	6	nail	nail	NOUN
dpc-2653	256	7	has	have	AUX
dpc-2653	256	8	been	be	AUX
dpc-2653	256	9	described	describe	VERB
dpc-2653	256	10	in	in	ADP
dpc-2653	256	11	association	association	NOUN
dpc-2653	256	12	with	with	ADP
dpc-2653	256	13	nivolumab	nivolumab	NOUN
dpc-2653	256	14	,	,	PUNCT
dpc-2653	256	15	clinically	clinically	ADV
dpc-2653	256	16	characterized	characterize	VERB
dpc-2653	256	17	by	by	ADP
dpc-2653	256	18	nail	nail	NOUN
dpc-2653	256	19	thickening	thickening	NOUN
dpc-2653	256	20	combined	combine	VERB
dpc-2653	256	21	with	with	ADP
dpc-2653	256	22	periungual	periungual	ADJ
dpc-2653	256	23	erythema	erythema	NOUN
dpc-2653	256	24	[	[	X
dpc-2653	256	25	43	43	NUM
dpc-2653	256	26	,	,	PUNCT
dpc-2653	256	27	45	45	NUM
dpc-2653	256	28	]	]	PUNCT
dpc-2653	256	29	.	.	PUNCT
dpc-2653	257	1	table	table	NOUN
dpc-2653	257	2	4	4	NUM
dpc-2653	257	3	.	.	PUNCT
dpc-2653	257	4	challenges	challenge	NOUN
dpc-2653	257	5	in	in	ADP
dpc-2653	257	6	the	the	DET
dpc-2653	257	7	diagnosis	diagnosis	NOUN
dpc-2653	257	8	of	of	ADP
dpc-2653	257	9	drug	drug	NOUN
dpc-2653	257	10	-	-	PUNCT
dpc-2653	257	11	induced	induce	VERB
dpc-2653	257	12	nail	nail	NOUN
dpc-2653	257	13	toxicity	toxicity	NOUN
dpc-2653	257	14	.	.	PUNCT
dpc-2653	258	1	several	several	ADJ
dpc-2653	258	2	factors	factor	NOUN
dpc-2653	258	3	may	may	AUX
dpc-2653	258	4	pose	pose	VERB
dpc-2653	258	5	diagnostic	diagnostic	ADJ
dpc-2653	258	6	difficulties	difficulty	NOUN
dpc-2653	258	7	in	in	ADP
dpc-2653	258	8	the	the	DET
dpc-2653	258	9	scenario	scenario	NOUN
dpc-2653	258	10	of	of	ADP
dpc-2653	258	11	drug	drug	NOUN
dpc-2653	258	12	-	-	PUNCT
dpc-2653	258	13	induced	induce	VERB
dpc-2653	258	14	nail	nail	NOUN
dpc-2653	258	15	toxicity	toxicity	NOUN
dpc-2653	258	16	[	[	X
dpc-2653	258	17	2	2	NUM
dpc-2653	258	18	,	,	PUNCT
dpc-2653	258	19	3	3	NUM
dpc-2653	258	20	,	,	PUNCT
dpc-2653	258	21	7	7	NUM
dpc-2653	258	22	,	,	PUNCT
dpc-2653	258	23	81	81	NUM
dpc-2653	258	24	]	]	SYM
dpc-2653	258	25	1	1	X
dpc-2653	258	26	.	.	PUNCT
dpc-2653	258	27	nail	nail	NOUN
dpc-2653	258	28	changes	change	NOUN
dpc-2653	258	29	may	may	AUX
dpc-2653	258	30	appear	appear	VERB
dpc-2653	258	31	several	several	ADJ
dpc-2653	258	32	weeks	week	NOUN
dpc-2653	258	33	after	after	ADP
dpc-2653	258	34	drug	drug	NOUN
dpc-2653	258	35	intake	intake	NOUN
dpc-2653	258	36	,	,	PUNCT
dpc-2653	258	37	due	due	ADP
dpc-2653	258	38	to	to	ADP
dpc-2653	258	39	the	the	DET
dpc-2653	258	40	kinetics	kinetic	NOUN
dpc-2653	258	41	of	of	ADP
dpc-2653	258	42	nail	nail	NOUN
dpc-2653	258	43	formation	formation	NOUN
dpc-2653	258	44	and	and	CCONJ
dpc-2653	258	45	the	the	DET
dpc-2653	258	46	slow	slow	ADJ
dpc-2653	258	47	growth	growth	NOUN
dpc-2653	258	48	rate	rate	NOUN
dpc-2653	258	49	of	of	ADP
dpc-2653	258	50	the	the	DET
dpc-2653	258	51	nail	nail	NOUN
dpc-2653	258	52	plate	plate	NOUN
dpc-2653	258	53	2	2	NUM
dpc-2653	258	54	.	.	PUNCT
dpc-2653	259	1	patients	patient	NOUN
dpc-2653	259	2	are	be	AUX
dpc-2653	259	3	often	often	ADV
dpc-2653	259	4	on	on	ADP
dpc-2653	259	5	multiple	multiple	ADJ
dpc-2653	259	6	potentially	potentially	ADV
dpc-2653	259	7	causative	causative	ADJ
dpc-2653	259	8	medications	medication	NOUN
dpc-2653	259	9	3	3	NUM
dpc-2653	259	10	.	.	X
dpc-2653	259	11	symptoms	symptom	NOUN
dpc-2653	259	12	often	often	ADV
dpc-2653	259	13	improve	improve	VERB
dpc-2653	259	14	or	or	CCONJ
dpc-2653	259	15	resolve	resolve	VERB
dpc-2653	259	16	without	without	ADP
dpc-2653	259	17	drug	drug	NOUN
dpc-2653	259	18	withdrawal	withdrawal	NOUN
dpc-2653	259	19	4	4	NUM
dpc-2653	259	20	.	.	PUNCT
dpc-2653	260	1	rechallenge	rechallenge	NOUN
dpc-2653	260	2	is	be	AUX
dpc-2653	260	3	commonly	commonly	ADV
dpc-2653	260	4	uneventful	uneventful	ADJ
dpc-2653	260	5	5	5	NUM
dpc-2653	260	6	.	.	PUNCT
dpc-2653	260	7	non	non	ADJ
dpc-2653	260	8	-	-	ADJ
dpc-2653	260	9	drug	drug	ADJ
dpc-2653	260	10	causes	cause	NOUN
dpc-2653	260	11	may	may	AUX
dpc-2653	260	12	be	be	AUX
dpc-2653	260	13	involved	involve	VERB
dpc-2653	260	14	6	6	NUM
dpc-2653	260	15	.	.	PUNCT
dpc-2653	261	1	abnormalities	abnormality	NOUN
dpc-2653	261	2	do	do	AUX
dpc-2653	261	3	not	not	PART
dpc-2653	261	4	necessarily	necessarily	ADV
dpc-2653	261	5	involve	involve	VERB
dpc-2653	261	6	all	all	DET
dpc-2653	261	7	nails	nail	NOUN
dpc-2653	261	8	7	7	NUM
dpc-2653	261	9	.	.	PUNCT
dpc-2653	262	1	poor	poor	ADJ
dpc-2653	262	2	understanding	understanding	NOUN
dpc-2653	262	3	of	of	ADP
dpc-2653	262	4	the	the	DET
dpc-2653	262	5	pathogenesis	pathogenesis	NOUN
dpc-2653	262	6	of	of	ADP
dpc-2653	262	7	nail	nail	NOUN
dpc-2653	262	8	damage	damage	NOUN
dpc-2653	262	9	.	.	PUNCT
dpc-2653	263	1	review	review	NOUN
dpc-2653	263	2	|	|	ADV
dpc-2653	263	3	dermatol	dermatol	ADJ
dpc-2653	263	4	pract	pract	NOUN
dpc-2653	263	5	concept	concept	NOUN
dpc-2653	263	6	.	.	PUNCT
dpc-2653	264	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	264	2	11	11	NUM
dpc-2653	264	3	table	table	NOUN
dpc-2653	264	4	5	5	NUM
dpc-2653	264	5	.	.	PUNCT
dpc-2653	265	1	nail	nail	NOUN
dpc-2653	265	2	changes	change	NOUN
dpc-2653	265	3	presented	present	VERB
dpc-2653	265	4	in	in	ADP
dpc-2653	265	5	association	association	NOUN
dpc-2653	265	6	with	with	ADP
dpc-2653	265	7	the	the	DET
dpc-2653	265	8	potentially	potentially	ADV
dpc-2653	265	9	responsible	responsible	ADJ
dpc-2653	265	10	anticancer	anticancer	NOUN
dpc-2653	265	11	regimen	regiman	NOUN
dpc-2653	265	12	.	.	PUNCT
dpc-2653	266	1	nail	nail	NOUN
dpc-2653	266	2	changes	change	NOUN
dpc-2653	266	3	conventional	conventional	ADJ
dpc-2653	266	4	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	266	5	drugs	drug	NOUN
dpc-2653	266	6	targeted	target	VERB
dpc-2653	266	7	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	266	8	drugs	drug	NOUN
dpc-2653	266	9	diffuse	diffuse	VERB
dpc-2653	266	10	hyper	hyper	ADJ
dpc-2653	266	11	-	-	ADJ
dpc-2653	266	12	pigmentation	pigmentation	ADJ
dpc-2653	266	13	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	266	14	,	,	PUNCT
dpc-2653	266	15	vincristine	vincristine	NOUN
dpc-2653	266	16	,	,	PUNCT
dpc-2653	266	17	cisplatin	cisplatin	NOUN
dpc-2653	266	18	,	,	PUNCT
dpc-2653	266	19	carboplatin	carboplatin	NOUN
dpc-2653	266	20	,	,	PUNCT
dpc-2653	266	21	oxaliplatin	oxaliplatin	PROPN
dpc-2653	266	22	,	,	PUNCT
dpc-2653	266	23	5	5	NUM
dpc-2653	266	24	-	-	PUNCT
dpc-2653	266	25	fluorouracil	fluorouracil	NOUN
dpc-2653	266	26	,	,	PUNCT
dpc-2653	266	27	capecitabine	capecitabine	NOUN
dpc-2653	266	28	,	,	PUNCT
dpc-2653	266	29	doxorubicin	doxorubicin	PROPN
dpc-2653	266	30	,	,	PUNCT
dpc-2653	266	31	daunorubicin	daunorubicin	PROPN
dpc-2653	266	32	,	,	PUNCT
dpc-2653	266	33	bleomycin	bleomycin	PROPN
dpc-2653	266	34	,	,	PUNCT
dpc-2653	266	35	hydroxyurea	hydroxyurea	PROPN
dpc-2653	266	36	,	,	PUNCT
dpc-2653	266	37	busulfan	busulfan	NOUN
dpc-2653	266	38	,	,	PUNCT
dpc-2653	266	39	docetaxel	docetaxel	NOUN
dpc-2653	266	40	,	,	PUNCT
dpc-2653	266	41	paclitaxel	paclitaxel	NOUN
dpc-2653	266	42	,	,	PUNCT
dpc-2653	266	43	pemetrexed	pemetrexe	VERB
dpc-2653	266	44	,	,	PUNCT
dpc-2653	266	45	etoposide	etoposide	NOUN
dpc-2653	266	46	combination	combination	NOUN
dpc-2653	266	47	of	of	ADP
dpc-2653	266	48	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	266	49	/	/	SYM
dpc-2653	266	50	adriamycin/	adriamycin/	NUM
dpc-2653	266	51	vincristine	vincristine	NOUN
dpc-2653	266	52	/	/	SYM
dpc-2653	266	53	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	266	54	/	/	SYM
dpc-2653	266	55	adriamycin/	adriamycin/	NUM
dpc-2653	266	56	docetaxel	docetaxel	PROPN
dpc-2653	266	57	imatinib	imatinib	NOUN
dpc-2653	266	58	longitudinal	longitudinal	ADJ
dpc-2653	266	59	melanonychia	melanonychia	NOUN
dpc-2653	266	60	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	266	61	,	,	PUNCT
dpc-2653	266	62	vincristine	vincristine	NOUN
dpc-2653	266	63	,	,	PUNCT
dpc-2653	266	64	bleomycin	bleomycin	PROPN
dpc-2653	266	65	,	,	PUNCT
dpc-2653	266	66	tegafur	tegafur	NOUN
dpc-2653	266	67	,	,	PUNCT
dpc-2653	266	68	combination	combination	NOUN
dpc-2653	266	69	of	of	ADP
dpc-2653	266	70	cyclophosphamide/	cyclophosphamide/	NUM
dpc-2653	266	71	adriamycin	adriamycin	NOUN
dpc-2653	266	72	/	/	SYM
dpc-2653	266	73	vincristine	vincristine	NOUN
dpc-2653	266	74	imatinib	imatinib	NOUN
dpc-2653	266	75	beau	beau	PROPN
dpc-2653	266	76	’s	’s	PART
dpc-2653	266	77	lines	line	NOUN
dpc-2653	266	78	docetaxel	docetaxel	PROPN
dpc-2653	266	79	,	,	PUNCT
dpc-2653	266	80	paclitaxel	paclitaxel	NOUN
dpc-2653	266	81	,	,	PUNCT
dpc-2653	266	82	cisplatin	cisplatin	NOUN
dpc-2653	266	83	,	,	PUNCT
dpc-2653	266	84	doxorubicin	doxorubicin	PROPN
dpc-2653	266	85	,	,	PUNCT
dpc-2653	266	86	bleomycin	bleomycin	PROPN
dpc-2653	266	87	,	,	PUNCT
dpc-2653	266	88	combination	combination	NOUN
dpc-2653	266	89	of	of	ADP
dpc-2653	266	90	epirubicin/	epirubicin/	NUM
dpc-2653	266	91	vincristine	vincristine	NOUN
dpc-2653	266	92	/	/	SYM
dpc-2653	266	93	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	266	94	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	266	95	/	/	SYM
dpc-2653	266	96	doxorubicin	doxorubicin	PROPN
dpc-2653	266	97	/	/	PUNCT
dpc-2653	266	98	fluorouracil	fluorouracil	PROPN
dpc-2653	266	99	onychomadesis	onychomadesis	NOUN
dpc-2653	266	100	paclitaxel	paclitaxel	PROPN
dpc-2653	266	101	,	,	PUNCT
dpc-2653	266	102	docetaxel	docetaxel	PROPN
dpc-2653	266	103	,	,	PUNCT
dpc-2653	266	104	capecitabine	capecitabine	NOUN
dpc-2653	266	105	,	,	PUNCT
dpc-2653	266	106	combination	combination	NOUN
dpc-2653	266	107	of	of	ADP
dpc-2653	266	108	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	266	109	/	/	SYM
dpc-2653	266	110	vincristine	vincristine	NOUN
dpc-2653	266	111	/	/	SYM
dpc-2653	266	112	procarbazine/	procarbazine/	PROPN
dpc-2653	266	113	prednisolone	prednisolone	PROPN
dpc-2653	266	114	mees	mees	PROPN
dpc-2653	266	115	’	'	PUNCT
dpc-2653	266	116	lines	line	NOUN
dpc-2653	266	117	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	266	118	,	,	PUNCT
dpc-2653	266	119	doxorubicin	doxorubicin	PROPN
dpc-2653	266	120	,	,	PUNCT
dpc-2653	266	121	vincristine	vincristine	NOUN
dpc-2653	266	122	,	,	PUNCT
dpc-2653	266	123	docetaxel	docetaxel	NOUN
dpc-2653	266	124	,	,	PUNCT
dpc-2653	266	125	paclitaxel	paclitaxel	NOUN
dpc-2653	266	126	,	,	PUNCT
dpc-2653	266	127	combination	combination	NOUN
dpc-2653	266	128	of	of	ADP
dpc-2653	266	129	cytarabine/	cytarabine/	NUM
dpc-2653	266	130	daunorubicin	daunorubicin	NOUN
dpc-2653	266	131	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	266	132	/	/	SYM
dpc-2653	266	133	doxorubicin	doxorubicin	PROPN
dpc-2653	266	134	/	/	SYM
dpc-2653	266	135	vincristine/	vincristine/	PROPN
dpc-2653	266	136	prednisolone	prednisolone	X
dpc-2653	266	137	(	(	PUNCT
dpc-2653	266	138	chop	chop	NOUN
dpc-2653	266	139	)	)	PUNCT
dpc-2653	266	140	muehrcke	muehrcke	PROPN
dpc-2653	266	141	’s	’s	PART
dpc-2653	266	142	lines	line	NOUN
dpc-2653	266	143	combination	combination	NOUN
dpc-2653	266	144	of	of	ADP
dpc-2653	266	145	cyclophosphamide/	cyclophosphamide/	NUM
dpc-2653	266	146	doxorubicin/5	doxorubicin/5	NOUN
dpc-2653	266	147	-	-	PUNCT
dpc-2653	266	148	fluorouracil	fluorouracil	NOUN
dpc-2653	266	149	vincristine	vincristine	NOUN
dpc-2653	266	150	/	/	SYM
dpc-2653	266	151	doxorubicin	doxorubicin	PROPN
dpc-2653	266	152	/	/	SYM
dpc-2653	266	153	dexamethasone	dexamethasone	NOUN
dpc-2653	266	154	cisplatin	cisplatin	NOUN
dpc-2653	266	155	,	,	PUNCT
dpc-2653	266	156	oxaliplatin	oxaliplatin	NOUN
dpc-2653	266	157	half	half	NOUN
dpc-2653	266	158	and	and	CCONJ
dpc-2653	266	159	half	half	NOUN
dpc-2653	266	160	nails	nail	NOUN
dpc-2653	266	161	(	(	PUNCT
dpc-2653	266	162	lindsay	lindsay	PROPN
dpc-2653	266	163	’s	’s	PART
dpc-2653	266	164	nails	nails	PROPN
dpc-2653	266	165	)	)	PUNCT
dpc-2653	266	166	5	5	NUM
dpc-2653	266	167	-	-	PUNCT
dpc-2653	266	168	fluorouracil	fluorouracil	NOUN
dpc-2653	266	169	onycholysis	onycholysis	NOUN
dpc-2653	266	170	docetaxel	docetaxel	NOUN
dpc-2653	266	171	,	,	PUNCT
dpc-2653	266	172	paclitaxel	paclitaxel	NOUN
dpc-2653	266	173	,	,	PUNCT
dpc-2653	266	174	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	266	175	,	,	PUNCT
dpc-2653	266	176	pemetrexed	pemetrexe	VERB
dpc-2653	266	177	,	,	PUNCT
dpc-2653	266	178	5	5	NUM
dpc-2653	266	179	-	-	PUNCT
dpc-2653	266	180	fluorouracil	fluorouracil	NOUN
dpc-2653	266	181	,	,	PUNCT
dpc-2653	266	182	capecitabine	capecitabine	NOUN
dpc-2653	266	183	cetuximab	cetuximab	NOUN
dpc-2653	266	184	,	,	PUNCT
dpc-2653	266	185	panitumumab	panitumumab	NOUN
dpc-2653	266	186	,	,	PUNCT
dpc-2653	266	187	erlotinib	erlotinib	NOUN
dpc-2653	266	188	,	,	PUNCT
dpc-2653	266	189	gefitinib	gefitinib	NOUN
dpc-2653	266	190	,	,	PUNCT
dpc-2653	266	191	necituumab	necituumab	NOUN
dpc-2653	266	192	,	,	PUNCT
dpc-2653	266	193	lapatinib	lapatinib	PROPN
dpc-2653	266	194	,	,	PUNCT
dpc-2653	266	195	afatinib	afatinib	NOUN
dpc-2653	266	196	,	,	PUNCT
dpc-2653	266	197	dacomitinib	dacomitinib	NOUN
dpc-2653	266	198	,	,	PUNCT
dpc-2653	266	199	trametinib	trametinib	NOUN
dpc-2653	266	200	,	,	PUNCT
dpc-2653	266	201	cobimetinib	cobimetinib	NOUN
dpc-2653	266	202	,	,	PUNCT
dpc-2653	266	203	selumetinib	selumetinib	NOUN
dpc-2653	266	204	,	,	PUNCT
dpc-2653	266	205	everolimus	everolimus	ADJ
dpc-2653	266	206	,	,	PUNCT
dpc-2653	266	207	temsirolimus	temsirolimus	NOUN
dpc-2653	266	208	,	,	PUNCT
dpc-2653	266	209	ibrutinib	ibrutinib	PROPN
dpc-2653	266	210	,	,	PUNCT
dpc-2653	266	211	vandetanib	vandetanib	PROPN
dpc-2653	266	212	paronychia	paronychia	PROPN
dpc-2653	266	213	fluorouracil	fluorouracil	PROPN
dpc-2653	266	214	,	,	PUNCT
dpc-2653	266	215	docetaxel	docetaxel	NOUN
dpc-2653	266	216	,	,	PUNCT
dpc-2653	266	217	paclitaxel	paclitaxel	NOUN
dpc-2653	266	218	,	,	PUNCT
dpc-2653	266	219	etoposide	etoposide	NOUN
dpc-2653	266	220	cetuximab	cetuximab	NOUN
dpc-2653	266	221	,	,	PUNCT
dpc-2653	266	222	panitumumab	panitumumab	NOUN
dpc-2653	266	223	,	,	PUNCT
dpc-2653	266	224	erlotinib	erlotinib	NOUN
dpc-2653	266	225	,	,	PUNCT
dpc-2653	266	226	gefitinib	gefitinib	NOUN
dpc-2653	266	227	,	,	PUNCT
dpc-2653	266	228	necituumab	necituumab	NOUN
dpc-2653	266	229	,	,	PUNCT
dpc-2653	266	230	lapatinib	lapatinib	PROPN
dpc-2653	266	231	,	,	PUNCT
dpc-2653	266	232	afatinib	afatinib	NOUN
dpc-2653	266	233	,	,	PUNCT
dpc-2653	266	234	dacomitinib	dacomitinib	NOUN
dpc-2653	266	235	,	,	PUNCT
dpc-2653	266	236	trametinib	trametinib	NOUN
dpc-2653	266	237	,	,	PUNCT
dpc-2653	266	238	cobimetinib	cobimetinib	NOUN
dpc-2653	266	239	,	,	PUNCT
dpc-2653	266	240	selumetinib	selumetinib	NOUN
dpc-2653	266	241	,	,	PUNCT
dpc-2653	266	242	everolimus	everolimus	ADJ
dpc-2653	266	243	,	,	PUNCT
dpc-2653	266	244	temsirolimus	temsirolimus	NOUN
dpc-2653	266	245	,	,	PUNCT
dpc-2653	266	246	vandetanib	vandetanib	PROPN
dpc-2653	266	247	subungual	subungual	ADJ
dpc-2653	266	248	hyperkeratosis	hyperkeratosis	PROPN
dpc-2653	266	249	docetaxel	docetaxel	NOUN
dpc-2653	266	250	,	,	PUNCT
dpc-2653	266	251	paclitaxel	paclitaxel	NOUN
dpc-2653	266	252	,	,	PUNCT
dpc-2653	266	253	fluorouracil	fluorouracil	NOUN
dpc-2653	266	254	pyogenic	pyogenic	ADJ
dpc-2653	266	255	granuloma	granuloma	PROPN
dpc-2653	266	256	docetaxel	docetaxel	NOUN
dpc-2653	266	257	,	,	PUNCT
dpc-2653	266	258	paclitaxel	paclitaxel	NOUN
dpc-2653	266	259	cetuximab	cetuximab	NOUN
dpc-2653	266	260	,	,	PUNCT
dpc-2653	266	261	panitumumab	panitumumab	NOUN
dpc-2653	266	262	,	,	PUNCT
dpc-2653	266	263	erlotinib	erlotinib	NOUN
dpc-2653	266	264	gefitinib	gefitinib	NOUN
dpc-2653	266	265	,	,	PUNCT
dpc-2653	266	266	necituumab	necituumab	NOUN
dpc-2653	266	267	,	,	PUNCT
dpc-2653	266	268	lapatinib	lapatinib	PROPN
dpc-2653	266	269	,	,	PUNCT
dpc-2653	266	270	afatinib	afatinib	NOUN
dpc-2653	266	271	,	,	PUNCT
dpc-2653	266	272	dacomitinib	dacomitinib	NOUN
dpc-2653	266	273	,	,	PUNCT
dpc-2653	266	274	trametinib	trametinib	NOUN
dpc-2653	266	275	,	,	PUNCT
dpc-2653	266	276	cobimetinib	cobimetinib	NOUN
dpc-2653	266	277	,	,	PUNCT
dpc-2653	266	278	selumetinib	selumetinib	NOUN
dpc-2653	266	279	,	,	PUNCT
dpc-2653	266	280	everolimus	everolimus	ADJ
dpc-2653	266	281	,	,	PUNCT
dpc-2653	266	282	temsirolimus	temsirolimus	NOUN
dpc-2653	266	283	,	,	PUNCT
dpc-2653	266	284	vandetanib	vandetanib	PROPN
dpc-2653	266	285	subungual	subungual	PROPN
dpc-2653	266	286	&	&	CCONJ
dpc-2653	266	287	splinter	splinter	VERB
dpc-2653	266	288	hemorrhage	hemorrhage	NOUN
dpc-2653	266	289	docetaxel	docetaxel	NOUN
dpc-2653	266	290	,	,	PUNCT
dpc-2653	266	291	paclitaxel	paclitaxel	PROPN
dpc-2653	266	292	vandetanib	vandetanib	PROPN
dpc-2653	266	293	,	,	PUNCT
dpc-2653	266	294	sunitinib	sunitinib	PROPN
dpc-2653	266	295	,	,	PUNCT
dpc-2653	266	296	sorafenib	sorafenib	NOUN
dpc-2653	266	297	,	,	PUNCT
dpc-2653	266	298	cabozantinib	cabozantinib	ADV
dpc-2653	266	299	,	,	PUNCT
dpc-2653	266	300	axitinib	axitinib	NOUN
dpc-2653	266	301	,	,	PUNCT
dpc-2653	266	302	pazotinib	pazotinib	NOUN
dpc-2653	266	303	,	,	PUNCT
dpc-2653	266	304	regorafenib	regorafenib	VERB
dpc-2653	266	305	brittle	brittle	ADJ
dpc-2653	266	306	nails	nail	NOUN
dpc-2653	266	307	docetaxel	docetaxel	NOUN
dpc-2653	266	308	,	,	PUNCT
dpc-2653	266	309	paclitaxel	paclitaxel	NOUN
dpc-2653	266	310	cetuximab	cetuximab	NOUN
dpc-2653	266	311	,	,	PUNCT
dpc-2653	266	312	panitumumab	panitumumab	NOUN
dpc-2653	266	313	,	,	PUNCT
dpc-2653	266	314	erlotinib	erlotinib	NOUN
dpc-2653	266	315	,	,	PUNCT
dpc-2653	266	316	gefitinib	gefitinib	NOUN
dpc-2653	266	317	,	,	PUNCT
dpc-2653	266	318	necituumab	necituumab	NOUN
dpc-2653	266	319	,	,	PUNCT
dpc-2653	266	320	lapatinib	lapatinib	PROPN
dpc-2653	266	321	,	,	PUNCT
dpc-2653	266	322	afatinib	afatinib	NOUN
dpc-2653	266	323	,	,	PUNCT
dpc-2653	266	324	dacomitinib	dacomitinib	NOUN
dpc-2653	266	325	,	,	PUNCT
dpc-2653	266	326	trametinib	trametinib	NOUN
dpc-2653	266	327	,	,	PUNCT
dpc-2653	266	328	cobimetinib	cobimetinib	NOUN
dpc-2653	266	329	,	,	PUNCT
dpc-2653	266	330	selumetinib	selumetinib	NOUN
dpc-2653	266	331	,	,	PUNCT
dpc-2653	266	332	everolimus	everolimus	ADJ
dpc-2653	266	333	temsirolimus	temsirolimus	NOUN
dpc-2653	266	334	,	,	PUNCT
dpc-2653	266	335	ibrutinib	ibrutinib	NOUN
dpc-2653	266	336	,	,	PUNCT
dpc-2653	266	337	sunitinib	sunitinib	NOUN
dpc-2653	266	338	,	,	PUNCT
dpc-2653	266	339	sorafenib	sorafenib	NOUN
dpc-2653	266	340	,	,	PUNCT
dpc-2653	266	341	cabozantinib	cabozantinib	ADV
dpc-2653	266	342	,	,	PUNCT
dpc-2653	266	343	axitinib	axitinib	NOUN
dpc-2653	266	344	,	,	PUNCT
dpc-2653	266	345	pazotinib	pazotinib	NOUN
dpc-2653	266	346	,	,	PUNCT
dpc-2653	266	347	regorafenib	regorafenib	PROPN
dpc-2653	266	348	onychorrhexis	onychorrhexis	ADP
dpc-2653	266	349	docetaxel	docetaxel	NOUN
dpc-2653	266	350	,	,	PUNCT
dpc-2653	266	351	paclitaxel	paclitaxel	PROPN
dpc-2653	266	352	ibrutinib	ibrutinib	PROPN
dpc-2653	266	353	koilonychia	koilonychia	PROPN
dpc-2653	266	354	docetaxel	docetaxel	NOUN
dpc-2653	266	355	,	,	PUNCT
dpc-2653	266	356	paclitaxel	paclitaxel	VERB
dpc-2653	266	357	12	12	NUM
dpc-2653	266	358	review	review	NOUN
dpc-2653	266	359	|	|	ADV
dpc-2653	266	360	dermatol	dermatol	ADJ
dpc-2653	266	361	pract	pract	NOUN
dpc-2653	266	362	concept	concept	NOUN
dpc-2653	266	363	.	.	PUNCT
dpc-2653	267	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	267	2	true	true	ADJ
dpc-2653	267	3	leukonychia	leukonychia	NOUN
dpc-2653	267	4	(	(	PUNCT
dpc-2653	267	5	white	white	ADJ
dpc-2653	267	6	opaque	opaque	ADJ
dpc-2653	267	7	coloration	coloration	NOUN
dpc-2653	267	8	total	total	NOUN
dpc-2653	267	9	or	or	CCONJ
dpc-2653	267	10	transverse	transverse	ADJ
dpc-2653	267	11	:	:	PUNCT
dpc-2653	267	12	mees	mees	PROPN
dpc-2653	267	13	’	'	PUNCT
dpc-2653	267	14	lines	line	NOUN
dpc-2653	267	15	)	)	PUNCT
dpc-2653	267	16	results	result	NOUN
dpc-2653	267	17	from	from	ADP
dpc-2653	267	18	altered	altered	ADJ
dpc-2653	267	19	keratinization	keratinization	NOUN
dpc-2653	267	20	of	of	ADP
dpc-2653	267	21	the	the	DET
dpc-2653	267	22	distal	distal	ADJ
dpc-2653	267	23	nail	nail	NOUN
dpc-2653	267	24	matrix	matrix	NOUN
dpc-2653	267	25	.	.	PUNCT
dpc-2653	268	1	parakeratotic	parakeratotic	ADJ
dpc-2653	268	2	nuclei	nucleus	NOUN
dpc-2653	268	3	are	be	AUX
dpc-2653	268	4	retained	retain	VERB
dpc-2653	268	5	in	in	ADP
dpc-2653	268	6	the	the	DET
dpc-2653	268	7	nail	nail	NOUN
dpc-2653	268	8	plate	plate	NOUN
dpc-2653	268	9	and	and	CCONJ
dpc-2653	268	10	thus	thus	ADV
dpc-2653	268	11	the	the	DET
dpc-2653	268	12	nail	nail	NOUN
dpc-2653	268	13	appears	appear	VERB
dpc-2653	268	14	opaque	opaque	ADJ
dpc-2653	268	15	and	and	CCONJ
dpc-2653	268	16	white	white	ADJ
dpc-2653	268	17	in	in	ADP
dpc-2653	268	18	color	color	NOUN
dpc-2653	268	19	owing	owe	VERB
dpc-2653	268	20	to	to	ADP
dpc-2653	268	21	the	the	DET
dpc-2653	268	22	diffraction	diffraction	NOUN
dpc-2653	268	23	of	of	ADP
dpc-2653	268	24	light	light	NOUN
dpc-2653	268	25	by	by	ADP
dpc-2653	268	26	parakeratotic	parakeratotic	ADJ
dpc-2653	268	27	cells	cell	NOUN
dpc-2653	268	28	.	.	PUNCT
dpc-2653	269	1	true	true	ADJ
dpc-2653	269	2	leukonychia	leukonychia	NOUN
dpc-2653	269	3	does	do	AUX
dpc-2653	269	4	not	not	PART
dpc-2653	269	5	disappear	disappear	VERB
dpc-2653	269	6	with	with	ADP
dpc-2653	269	7	pressure	pressure	NOUN
dpc-2653	269	8	and	and	CCONJ
dpc-2653	269	9	moves	move	VERB
dpc-2653	269	10	distally	distally	ADV
dpc-2653	269	11	as	as	SCONJ
dpc-2653	269	12	the	the	DET
dpc-2653	269	13	nail	nail	NOUN
dpc-2653	269	14	grows	grow	VERB
dpc-2653	269	15	.	.	PUNCT
dpc-2653	270	1	mees	mees	PROPN
dpc-2653	270	2	’	'	PUNCT
dpc-2653	270	3	lines	line	NOUN
dpc-2653	270	4	are	be	AUX
dpc-2653	270	5	transverse	transverse	ADJ
dpc-2653	270	6	white	white	ADJ
dpc-2653	270	7	,	,	PUNCT
dpc-2653	270	8	non	non	ADJ
dpc-2653	270	9	-	-	ADJ
dpc-2653	270	10	blanching	blanch	VERB
dpc-2653	270	11	parallel	parallel	ADJ
dpc-2653	270	12	lines	line	NOUN
dpc-2653	270	13	to	to	ADP
dpc-2653	270	14	the	the	DET
dpc-2653	270	15	lunula	lunula	NOUN
dpc-2653	270	16	across	across	ADP
dpc-2653	270	17	the	the	DET
dpc-2653	270	18	entire	entire	ADJ
dpc-2653	270	19	nail	nail	NOUN
dpc-2653	270	20	bed	bed	NOUN
dpc-2653	270	21	and	and	CCONJ
dpc-2653	270	22	have	have	VERB
dpc-2653	270	23	no	no	DET
dpc-2653	270	24	palpable	palpable	ADJ
dpc-2653	270	25	ridges	ridge	NOUN
dpc-2653	270	26	[	[	PUNCT
dpc-2653	270	27	63	63	NUM
dpc-2653	270	28	,	,	PUNCT
dpc-2653	270	29	64	64	NUM
dpc-2653	270	30	]	]	PUNCT
dpc-2653	270	31	.	.	PUNCT
dpc-2653	271	1	in	in	ADP
dpc-2653	271	2	chemotherapy	chemotherapy	NOUN
dpc-2653	271	3	-	-	PUNCT
dpc-2653	271	4	induced	induce	VERB
dpc-2653	271	5	true	true	ADJ
dpc-2653	271	6	transverse	transverse	NOUN
dpc-2653	271	7	leukonychia	leukonychia	NOUN
dpc-2653	271	8	,	,	PUNCT
dpc-2653	271	9	the	the	DET
dpc-2653	271	10	sessions	session	NOUN
dpc-2653	271	11	of	of	ADP
dpc-2653	271	12	transverse	transverse	NOUN
dpc-2653	271	13	white	white	ADJ
dpc-2653	271	14	bands	band	NOUN
dpc-2653	271	15	and	and	CCONJ
dpc-2653	271	16	the	the	DET
dpc-2653	271	17	distance	distance	NOUN
dpc-2653	271	18	between	between	ADP
dpc-2653	271	19	them	they	PRON
dpc-2653	271	20	seemed	seem	VERB
dpc-2653	271	21	to	to	PART
dpc-2653	271	22	coincide	coincide	VERB
dpc-2653	271	23	with	with	ADP
dpc-2653	271	24	the	the	DET
dpc-2653	271	25	number	number	NOUN
dpc-2653	271	26	and	and	CCONJ
dpc-2653	271	27	duration	duration	NOUN
dpc-2653	271	28	of	of	ADP
dpc-2653	271	29	chemotherapy	chemotherapy	NOUN
dpc-2653	271	30	cycles	cycle	NOUN
dpc-2653	271	31	,	,	PUNCT
dpc-2653	271	32	respectively	respectively	ADV
dpc-2653	271	33	.	.	PUNCT
dpc-2653	272	1	apparent	apparent	ADJ
dpc-2653	272	2	leukonychia	leukonychia	NOUN
dpc-2653	272	3	(	(	PUNCT
dpc-2653	272	4	white	white	ADJ
dpc-2653	272	5	transparent	transparent	ADJ
dpc-2653	272	6	coloration	coloration	NOUN
dpc-2653	272	7	)	)	PUNCT
dpc-2653	272	8	is	be	AUX
dpc-2653	272	9	observed	observe	VERB
dpc-2653	272	10	because	because	SCONJ
dpc-2653	272	11	of	of	ADP
dpc-2653	272	12	changes	change	NOUN
dpc-2653	272	13	in	in	ADP
dpc-2653	272	14	the	the	DET
dpc-2653	272	15	nail	nail	NOUN
dpc-2653	272	16	bed	bed	NOUN
dpc-2653	272	17	vasculature	vasculature	NOUN
dpc-2653	272	18	on	on	ADP
dpc-2653	272	19	pressure	pressure	NOUN
dpc-2653	272	20	,	,	PUNCT
dpc-2653	272	21	visible	visible	ADJ
dpc-2653	272	22	through	through	ADP
dpc-2653	272	23	the	the	DET
dpc-2653	272	24	translucent	translucent	ADJ
dpc-2653	272	25	nail	nail	NOUN
dpc-2653	272	26	plate	plate	NOUN
dpc-2653	272	27	.	.	PUNCT
dpc-2653	273	1	true	true	ADJ
dpc-2653	273	2	and	and	CCONJ
dpc-2653	273	3	apparent	apparent	ADJ
dpc-2653	273	4	leukonychia	leukonychia	NOUN
dpc-2653	273	5	may	may	AUX
dpc-2653	273	6	be	be	AUX
dpc-2653	273	7	differentiated	differentiate	VERB
dpc-2653	273	8	clinically	clinically	ADV
dpc-2653	273	9	by	by	ADP
dpc-2653	273	10	diascopy	diascopy	NOUN
dpc-2653	273	11	.	.	PUNCT
dpc-2653	274	1	the	the	DET
dpc-2653	274	2	whitish	whitish	ADJ
dpc-2653	274	3	discoloration	discoloration	NOUN
dpc-2653	274	4	disappears	disappear	VERB
dpc-2653	274	5	(	(	PUNCT
dpc-2653	274	6	or	or	CCONJ
dpc-2653	274	7	fades	fade	VERB
dpc-2653	274	8	)	)	PUNCT
dpc-2653	274	9	with	with	ADP
dpc-2653	274	10	digital	digital	ADJ
dpc-2653	274	11	compression	compression	NOUN
dpc-2653	274	12	and	and	CCONJ
dpc-2653	274	13	is	be	AUX
dpc-2653	274	14	not	not	PART
dpc-2653	274	15	modified	modify	VERB
dpc-2653	274	16	by	by	ADP
dpc-2653	274	17	nail	nail	NOUN
dpc-2653	274	18	growth	growth	NOUN
dpc-2653	274	19	.	.	PUNCT
dpc-2653	275	1	apparent	apparent	ADJ
dpc-2653	275	2	leukonychia	leukonychia	NOUN
dpc-2653	275	3	can	can	AUX
dpc-2653	275	4	present	present	VERB
dpc-2653	275	5	as	as	ADP
dpc-2653	275	6	three	three	NUM
dpc-2653	275	7	different	different	ADJ
dpc-2653	275	8	clinical	clinical	ADJ
dpc-2653	275	9	types	type	NOUN
dpc-2653	275	10	:	:	PUNCT
dpc-2653	275	11	muehrcke	muehrcke	NOUN
dpc-2653	275	12	’s	’s	PART
dpc-2653	275	13	lines	line	NOUN
dpc-2653	275	14	(	(	PUNCT
dpc-2653	275	15	the	the	DET
dpc-2653	275	16	most	most	ADV
dpc-2653	275	17	frequent	frequent	ADJ
dpc-2653	275	18	form	form	NOUN
dpc-2653	275	19	in	in	ADP
dpc-2653	275	20	association	association	NOUN
dpc-2653	275	21	with	with	ADP
dpc-2653	275	22	chemotherapy	chemotherapy	NOUN
dpc-2653	275	23	)	)	PUNCT
dpc-2653	275	24	,	,	PUNCT
dpc-2653	275	25	half	half	DET
dpc-2653	275	26	and	and	CCONJ
dpc-2653	275	27	half	half	ADJ
dpc-2653	275	28	nails	nail	NOUN
dpc-2653	275	29	(	(	PUNCT
dpc-2653	275	30	lindsay	lindsay	PROPN
dpc-2653	275	31	’s	’s	PART
dpc-2653	275	32	nails	nail	NOUN
dpc-2653	275	33	)	)	PUNCT
dpc-2653	275	34	,	,	PUNCT
dpc-2653	275	35	or	or	CCONJ
dpc-2653	275	36	terry	terry	PROPN
dpc-2653	275	37	’s	’s	PART
dpc-2653	275	38	nails	nails	PROPN
dpc-2653	275	39	.	.	PUNCT
dpc-2653	276	1	a.	a.	PROPN
dpc-2653	276	2	muehrcke	muehrcke	PROPN
dpc-2653	276	3	’s	’s	PART
dpc-2653	276	4	lines	line	NOUN
dpc-2653	276	5	(	(	PUNCT
dpc-2653	276	6	the	the	DET
dpc-2653	276	7	most	most	ADV
dpc-2653	276	8	frequent	frequent	ADJ
dpc-2653	276	9	form	form	NOUN
dpc-2653	276	10	in	in	ADP
dpc-2653	276	11	association	association	NOUN
dpc-2653	276	12	with	with	ADP
dpc-2653	276	13	chemotherapy	chemotherapy	NOUN
dpc-2653	276	14	)	)	PUNCT
dpc-2653	276	15	are	be	AUX
dpc-2653	276	16	present	present	ADJ
dpc-2653	276	17	as	as	ADP
dpc-2653	276	18	multiple	multiple	ADJ
dpc-2653	276	19	,	,	PUNCT
dpc-2653	276	20	paired	pair	VERB
dpc-2653	276	21	,	,	PUNCT
dpc-2653	276	22	transverse	transverse	ADJ
dpc-2653	276	23	,	,	PUNCT
dpc-2653	276	24	whitish	whitish	ADJ
dpc-2653	276	25	bands	band	NOUN
dpc-2653	276	26	,	,	PUNCT
dpc-2653	276	27	parallel	parallel	ADJ
dpc-2653	276	28	to	to	ADP
dpc-2653	276	29	the	the	DET
dpc-2653	276	30	lunula	lunula	NOUN
dpc-2653	276	31	.	.	PUNCT
dpc-2653	277	1	chen	chen	PROPN
dpc-2653	277	2	et	et	PROPN
dpc-2653	277	3	al	al	PROPN
dpc-2653	277	4	.	.	PUNCT
dpc-2653	278	1	[	[	X
dpc-2653	278	2	6	6	NUM
dpc-2653	278	3	]	]	PUNCT
dpc-2653	278	4	found	find	VERB
dpc-2653	278	5	muehrcke	muehrcke	NOUN
dpc-2653	278	6	’s	’s	PART
dpc-2653	278	7	lines	line	NOUN
dpc-2653	278	8	as	as	ADP
dpc-2653	278	9	the	the	DET
dpc-2653	278	10	most	most	ADV
dpc-2653	278	11	common	common	ADJ
dpc-2653	278	12	nail	nail	NOUN
dpc-2653	278	13	toxicity	toxicity	NOUN
dpc-2653	278	14	of	of	ADP
dpc-2653	278	15	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	278	16	drugs	drug	NOUN
dpc-2653	278	17	in	in	ADP
dpc-2653	278	18	children	child	NOUN
dpc-2653	278	19	.	.	PUNCT
dpc-2653	279	1	this	this	DET
dpc-2653	279	2	change	change	NOUN
dpc-2653	279	3	is	be	AUX
dpc-2653	279	4	commonly	commonly	ADV
dpc-2653	279	5	seen	see	VERB
dpc-2653	279	6	after	after	ADP
dpc-2653	279	7	chemotherapy	chemotherapy	NOUN
dpc-2653	279	8	and	and	CCONJ
dpc-2653	279	9	in	in	ADP
dpc-2653	279	10	chronic	chronic	ADJ
dpc-2653	279	11	hypoalbuminemia	hypoalbuminemia	NOUN
dpc-2653	279	12	of	of	ADP
dpc-2653	279	13	less	less	ADJ
dpc-2653	279	14	than	than	ADP
dpc-2653	279	15	2	2	NUM
dpc-2653	279	16	mg	mg	PROPN
dpc-2653	279	17	/	/	SYM
dpc-2653	279	18	dl	dl	PROPN
dpc-2653	279	19	(	(	PUNCT
dpc-2653	279	20	seen	see	VERB
dpc-2653	279	21	in	in	ADP
dpc-2653	279	22	nephrotic	nephrotic	ADJ
dpc-2653	279	23	syndrome	syndrome	NOUN
dpc-2653	279	24	,	,	PUNCT
dpc-2653	279	25	glomerulonephritis	glomerulonephritis	NOUN
dpc-2653	279	26	,	,	PUNCT
dpc-2653	279	27	liver	liver	NOUN
dpc-2653	279	28	disease	disease	NOUN
dpc-2653	279	29	,	,	PUNCT
dpc-2653	279	30	and	and	CCONJ
dpc-2653	279	31	malnutrition	malnutrition	NOUN
dpc-2653	279	32	)	)	PUNCT
dpc-2653	279	33	,	,	PUNCT
dpc-2653	279	34	and	and	CCONJ
dpc-2653	279	35	is	be	AUX
dpc-2653	279	36	commonly	commonly	ADV
dpc-2653	279	37	found	find	VERB
dpc-2653	279	38	on	on	ADP
dpc-2653	279	39	the	the	DET
dpc-2653	279	40	second	second	ADJ
dpc-2653	279	41	,	,	PUNCT
dpc-2653	279	42	third	third	ADJ
dpc-2653	279	43	,	,	PUNCT
dpc-2653	279	44	and	and	CCONJ
dpc-2653	279	45	fourth	fourth	ADJ
dpc-2653	279	46	fingernails	fingernail	NOUN
dpc-2653	279	47	.	.	PUNCT
dpc-2653	280	1	thumbnail	thumbnail	NOUN
dpc-2653	280	2	involvement	involvement	NOUN
dpc-2653	280	3	is	be	AUX
dpc-2653	280	4	rare	rare	ADJ
dpc-2653	280	5	.	.	PUNCT
dpc-2653	281	1	the	the	DET
dpc-2653	281	2	lines	line	NOUN
dpc-2653	281	3	tend	tend	VERB
dpc-2653	281	4	to	to	PART
dpc-2653	281	5	resolve	resolve	VERB
dpc-2653	281	6	with	with	ADP
dpc-2653	281	7	correction	correction	NOUN
dpc-2653	281	8	of	of	ADP
dpc-2653	281	9	hypoalbuminemia	hypoalbuminemia	NOUN
dpc-2653	281	10	.	.	PUNCT
dpc-2653	282	1	the	the	DET
dpc-2653	282	2	exact	exact	ADJ
dpc-2653	282	3	pathogenesis	pathogenesis	NOUN
dpc-2653	282	4	is	be	AUX
dpc-2653	282	5	unknown	unknown	ADJ
dpc-2653	282	6	,	,	PUNCT
dpc-2653	282	7	but	but	CCONJ
dpc-2653	282	8	the	the	DET
dpc-2653	282	9	suggested	suggest	VERB
dpc-2653	282	10	reasons	reason	NOUN
dpc-2653	282	11	are	be	AUX
dpc-2653	282	12	edema	edema	NOUN
dpc-2653	282	13	of	of	ADP
dpc-2653	282	14	the	the	DET
dpc-2653	282	15	nail	nail	NOUN
dpc-2653	282	16	bed	bed	NOUN
dpc-2653	282	17	,	,	PUNCT
dpc-2653	282	18	which	which	PRON
dpc-2653	282	19	occurs	occur	VERB
dpc-2653	282	20	due	due	ADJ
dpc-2653	282	21	to	to	ADP
dpc-2653	282	22	hypoalbuminemia	hypoalbuminemia	NOUN
dpc-2653	282	23	,	,	PUNCT
dpc-2653	282	24	and	and	CCONJ
dpc-2653	282	25	an	an	DET
dpc-2653	282	26	alteration	alteration	NOUN
dpc-2653	282	27	of	of	ADP
dpc-2653	282	28	nail	nail	NOUN
dpc-2653	282	29	plate	plate	NOUN
dpc-2653	282	30	attachment	attachment	NOUN
dpc-2653	282	31	to	to	ADP
dpc-2653	282	32	the	the	DET
dpc-2653	282	33	nail	nail	NOUN
dpc-2653	282	34	bed	bed	NOUN
dpc-2653	282	35	,	,	PUNCT
dpc-2653	282	36	which	which	PRON
dpc-2653	282	37	occurs	occur	VERB
dpc-2653	282	38	due	due	ADJ
dpc-2653	282	39	to	to	PART
dpc-2653	282	40	vascular	vascular	VERB
dpc-2653	282	41	compromise	compromise	NOUN
dpc-2653	282	42	following	follow	VERB
dpc-2653	282	43	chemotherapy	chemotherapy	NOUN
dpc-2653	283	1	[	[	X
dpc-2653	283	2	6	6	NUM
dpc-2653	283	3	]	]	PUNCT
dpc-2653	283	4	.	.	PUNCT
dpc-2653	284	1	b.	b.	PROPN
dpc-2653	284	2	half	half	NOUN
dpc-2653	284	3	and	and	CCONJ
dpc-2653	284	4	half	half	ADJ
dpc-2653	284	5	nails	nail	NOUN
dpc-2653	284	6	(	(	PUNCT
dpc-2653	284	7	lindsay	lindsay	PROPN
dpc-2653	284	8	’s	’s	PART
dpc-2653	284	9	nails	nail	NOUN
dpc-2653	284	10	)	)	PUNCT
dpc-2653	284	11	where	where	SCONJ
dpc-2653	284	12	there	there	PRON
dpc-2653	284	13	is	be	VERB
dpc-2653	284	14	a	a	DET
dpc-2653	284	15	definite	definite	ADJ
dpc-2653	284	16	border	border	NOUN
dpc-2653	284	17	between	between	ADP
dpc-2653	284	18	the	the	DET
dpc-2653	284	19	proximal	proximal	ADJ
dpc-2653	284	20	area	area	NOUN
dpc-2653	284	21	(	(	PUNCT
dpc-2653	284	22	opaque	opaque	ADJ
dpc-2653	284	23	white	white	NOUN
dpc-2653	284	24	)	)	PUNCT
dpc-2653	284	25	and	and	CCONJ
dpc-2653	284	26	the	the	DET
dpc-2653	284	27	distal	distal	ADJ
dpc-2653	284	28	area	area	NOUN
dpc-2653	284	29	(	(	PUNCT
dpc-2653	284	30	pink	pink	ADJ
dpc-2653	284	31	or	or	CCONJ
dpc-2653	284	32	reddish	reddish	ADJ
dpc-2653	284	33	brown	brown	NOUN
dpc-2653	284	34	)	)	PUNCT
dpc-2653	284	35	occupying	occupy	VERB
dpc-2653	284	36	20%–60	20%–60	NUM
dpc-2653	284	37	%	%	NOUN
dpc-2653	284	38	of	of	ADP
dpc-2653	284	39	the	the	DET
dpc-2653	284	40	nail	nail	NOUN
dpc-2653	284	41	bed	bed	NOUN
dpc-2653	284	42	.	.	PUNCT
dpc-2653	285	1	distal	distal	ADJ
dpc-2653	285	2	red	red	ADJ
dpc-2653	285	3	-	-	PUNCT
dpc-2653	285	4	brown	brown	ADJ
dpc-2653	285	5	pigmentation	pigmentation	NOUN
dpc-2653	285	6	does	do	AUX
dpc-2653	285	7	not	not	PART
dpc-2653	285	8	fade	fade	VERB
dpc-2653	285	9	with	with	ADP
dpc-2653	285	10	pressure	pressure	NOUN
dpc-2653	285	11	.	.	PUNCT
dpc-2653	286	1	c.	c.	PROPN
dpc-2653	286	2	terry	terry	PROPN
dpc-2653	286	3	’s	’s	PART
dpc-2653	286	4	nails	nail	NOUN
dpc-2653	286	5	,	,	PUNCT
dpc-2653	286	6	where	where	SCONJ
dpc-2653	286	7	the	the	DET
dpc-2653	286	8	whole	whole	ADJ
dpc-2653	286	9	nail	nail	NOUN
dpc-2653	286	10	appears	appear	VERB
dpc-2653	286	11	white	white	ADJ
dpc-2653	286	12	,	,	PUNCT
dpc-2653	286	13	except	except	SCONJ
dpc-2653	286	14	a	a	DET
dpc-2653	286	15	1–2	1–2	NUM
dpc-2653	286	16	mm	mm	NOUN
dpc-2653	286	17	pink	pink	ADJ
dpc-2653	286	18	-	-	PUNCT
dpc-2653	286	19	to	to	ADP
dpc-2653	286	20	-	-	PUNCT
dpc-2653	286	21	brown	brown	ADJ
dpc-2653	286	22	distal	distal	ADJ
dpc-2653	286	23	band	band	NOUN
dpc-2653	286	24	,	,	PUNCT
dpc-2653	286	25	and	and	CCONJ
dpc-2653	286	26	the	the	DET
dpc-2653	286	27	lunula	lunula	NOUN
dpc-2653	286	28	may	may	AUX
dpc-2653	286	29	or	or	CCONJ
dpc-2653	286	30	may	may	AUX
dpc-2653	286	31	not	not	PART
dpc-2653	286	32	be	be	AUX
dpc-2653	286	33	visible	visible	ADJ
dpc-2653	286	34	.	.	PUNCT
dpc-2653	287	1	in	in	ADP
dpc-2653	287	2	most	most	ADJ
dpc-2653	287	3	cases	case	NOUN
dpc-2653	287	4	,	,	PUNCT
dpc-2653	287	5	leukonychia	leukonychia	NOUN
dpc-2653	287	6	involves	involve	VERB
dpc-2653	287	7	all	all	DET
dpc-2653	287	8	fingernails	fingernail	NOUN
dpc-2653	287	9	and	and	CCONJ
dpc-2653	287	10	may	may	AUX
dpc-2653	287	11	coexist	coexist	VERB
dpc-2653	287	12	with	with	ADP
dpc-2653	287	13	melanonychia	melanonychia	PROPN
dpc-2653	287	14	.	.	PUNCT
dpc-2653	288	1	it	it	PRON
dpc-2653	288	2	has	have	AUX
dpc-2653	288	3	been	be	AUX
dpc-2653	288	4	described	describe	VERB
dpc-2653	288	5	in	in	ADP
dpc-2653	288	6	association	association	NOUN
dpc-2653	288	7	with	with	ADP
dpc-2653	288	8	numerous	numerous	ADJ
dpc-2653	288	9	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	288	10	agents	agent	NOUN
dpc-2653	288	11	but	but	CCONJ
dpc-2653	288	12	correlated	correlate	VERB
dpc-2653	288	13	to	to	ADP
dpc-2653	288	14	the	the	DET
dpc-2653	288	15	extent	extent	NOUN
dpc-2653	288	16	of	of	ADP
dpc-2653	288	17	nail	nail	NOUN
dpc-2653	288	18	matrix	matrix	NOUN
dpc-2653	288	19	damage	damage	NOUN
dpc-2653	288	20	.	.	PUNCT
dpc-2653	289	1	the	the	DET
dpc-2653	289	2	width	width	NOUN
dpc-2653	289	3	is	be	AUX
dpc-2653	289	4	proportional	proportional	ADJ
dpc-2653	289	5	to	to	ADP
dpc-2653	289	6	the	the	DET
dpc-2653	289	7	duration	duration	NOUN
dpc-2653	289	8	of	of	ADP
dpc-2653	289	9	the	the	DET
dpc-2653	289	10	insult	insult	NOUN
dpc-2653	289	11	.	.	PUNCT
dpc-2653	290	1	beau	beau	PROPN
dpc-2653	290	2	’s	’s	PART
dpc-2653	290	3	lines	line	NOUN
dpc-2653	290	4	have	have	AUX
dpc-2653	290	5	been	be	AUX
dpc-2653	290	6	described	describe	VERB
dpc-2653	290	7	with	with	ADP
dpc-2653	290	8	nearly	nearly	ADV
dpc-2653	290	9	all	all	PRON
dpc-2653	290	10	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	290	11	agents	agent	NOUN
dpc-2653	290	12	,	,	PUNCT
dpc-2653	290	13	especially	especially	ADV
dpc-2653	290	14	when	when	SCONJ
dpc-2653	290	15	used	use	VERB
dpc-2653	290	16	in	in	ADP
dpc-2653	290	17	combination	combination	NOUN
dpc-2653	290	18	or	or	CCONJ
dpc-2653	290	19	with	with	ADP
dpc-2653	290	20	a	a	DET
dpc-2653	290	21	high	high	ADJ
dpc-2653	290	22	-	-	PUNCT
dpc-2653	290	23	dose	dose	NOUN
dpc-2653	290	24	regimen	regiman	NOUN
dpc-2653	290	25	.	.	PUNCT
dpc-2653	291	1	they	they	PRON
dpc-2653	291	2	are	be	AUX
dpc-2653	291	3	probably	probably	ADV
dpc-2653	291	4	the	the	DET
dpc-2653	291	5	most	most	ADV
dpc-2653	291	6	frequent	frequent	ADJ
dpc-2653	291	7	nail	nail	NOUN
dpc-2653	291	8	changes	change	NOUN
dpc-2653	291	9	noted	note	VERB
dpc-2653	291	10	in	in	ADP
dpc-2653	291	11	patients	patient	NOUN
dpc-2653	291	12	exposed	expose	VERB
dpc-2653	291	13	to	to	ADP
dpc-2653	291	14	chemotherapy	chemotherapy	NOUN
dpc-2653	291	15	[	[	X
dpc-2653	291	16	4648	4648	NUM
dpc-2653	291	17	]	]	PUNCT
dpc-2653	291	18	.	.	PUNCT
dpc-2653	292	1	beau	beau	PROPN
dpc-2653	292	2	’s	’s	PART
dpc-2653	292	3	lines	line	NOUN
dpc-2653	292	4	often	often	ADV
dpc-2653	292	5	affect	affect	VERB
dpc-2653	292	6	all	all	DET
dpc-2653	292	7	nails	nail	NOUN
dpc-2653	292	8	but	but	CCONJ
dpc-2653	292	9	are	be	AUX
dpc-2653	292	10	more	more	ADV
dpc-2653	292	11	frequent	frequent	ADJ
dpc-2653	292	12	in	in	ADP
dpc-2653	292	13	fingernails	fingernail	NOUN
dpc-2653	292	14	and	and	CCONJ
dpc-2653	292	15	appear	appear	VERB
dpc-2653	292	16	after	after	ADP
dpc-2653	292	17	a	a	DET
dpc-2653	292	18	few	few	ADJ
dpc-2653	292	19	weeks	week	NOUN
dpc-2653	292	20	of	of	ADP
dpc-2653	292	21	chemotherapy	chemotherapy	NOUN
dpc-2653	292	22	[	[	X
dpc-2653	292	23	4	4	NUM
dpc-2653	292	24	,	,	PUNCT
dpc-2653	292	25	55	55	NUM
dpc-2653	292	26	]	]	PUNCT
dpc-2653	292	27	.	.	PUNCT
dpc-2653	293	1	after	after	ADP
dpc-2653	293	2	repeated	repeat	VERB
dpc-2653	293	3	courses	course	NOUN
dpc-2653	293	4	of	of	ADP
dpc-2653	293	5	chemotherapy	chemotherapy	NOUN
dpc-2653	293	6	,	,	PUNCT
dpc-2653	293	7	several	several	ADJ
dpc-2653	293	8	depressions	depression	NOUN
dpc-2653	293	9	can	can	AUX
dpc-2653	293	10	be	be	AUX
dpc-2653	293	11	noted	note	VERB
dpc-2653	293	12	in	in	ADP
dpc-2653	293	13	the	the	DET
dpc-2653	293	14	same	same	ADJ
dpc-2653	293	15	nail	nail	NOUN
dpc-2653	293	16	.	.	PUNCT
dpc-2653	294	1	they	they	PRON
dpc-2653	294	2	move	move	VERB
dpc-2653	294	3	distally	distally	ADV
dpc-2653	294	4	with	with	ADP
dpc-2653	294	5	nail	nail	NOUN
dpc-2653	294	6	growth	growth	NOUN
dpc-2653	294	7	.	.	PUNCT
dpc-2653	295	1	the	the	DET
dpc-2653	295	2	presence	presence	NOUN
dpc-2653	295	3	of	of	ADP
dpc-2653	295	4	regular	regular	ADJ
dpc-2653	295	5	transverse	transverse	NOUN
dpc-2653	295	6	beau	beau	NOUN
dpc-2653	295	7	’s	’s	PART
dpc-2653	295	8	lines	line	NOUN
dpc-2653	295	9	in	in	ADP
dpc-2653	295	10	the	the	DET
dpc-2653	295	11	nail	nail	NOUN
dpc-2653	295	12	plate	plate	NOUN
dpc-2653	295	13	reflects	reflect	VERB
dpc-2653	295	14	the	the	DET
dpc-2653	295	15	temporary	temporary	ADJ
dpc-2653	295	16	cessation	cessation	NOUN
dpc-2653	295	17	of	of	ADP
dpc-2653	295	18	matrix	matrix	NOUN
dpc-2653	295	19	proliferation	proliferation	NOUN
dpc-2653	295	20	during	during	ADP
dpc-2653	295	21	each	each	DET
dpc-2653	295	22	chemotherapy	chemotherapy	NOUN
dpc-2653	295	23	cycle	cycle	NOUN
dpc-2653	295	24	.	.	PUNCT
dpc-2653	296	1	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	296	2	agents	agent	NOUN
dpc-2653	296	3	such	such	ADJ
dpc-2653	296	4	as	as	ADP
dpc-2653	296	5	docetaxel	docetaxel	NOUN
dpc-2653	296	6	,	,	PUNCT
dpc-2653	296	7	paclitaxel	paclitaxel	PROPN
dpc-2653	296	8	,	,	PUNCT
dpc-2653	296	9	a	a	DET
dpc-2653	296	10	combination	combination	NOUN
dpc-2653	296	11	of	of	ADP
dpc-2653	296	12	epirubicin	epirubicin	NOUN
dpc-2653	296	13	/	/	SYM
dpc-2653	296	14	vincristine	vincristine	NOUN
dpc-2653	296	15	/	/	SYM
dpc-2653	296	16	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	296	17	,	,	PUNCT
dpc-2653	296	18	and	and	CCONJ
dpc-2653	296	19	cyclophosphamide/	cyclophosphamide/	NUM
dpc-2653	296	20	doxorubicin	doxorubicin	PROPN
dpc-2653	296	21	/	/	PUNCT
dpc-2653	296	22	fluorouracil	fluorouracil	PROPN
dpc-2653	296	23	are	be	AUX
dpc-2653	296	24	associated	associate	VERB
dpc-2653	296	25	with	with	ADP
dpc-2653	296	26	beau	beau	PROPN
dpc-2653	296	27	’s	’s	PART
dpc-2653	296	28	lines	line	NOUN
dpc-2653	296	29	[	[	X
dpc-2653	296	30	4	4	NUM
dpc-2653	296	31	,	,	PUNCT
dpc-2653	296	32	56	56	NUM
dpc-2653	296	33	,	,	PUNCT
dpc-2653	296	34	57	57	NUM
dpc-2653	296	35	]	]	PUNCT
dpc-2653	296	36	(	(	PUNCT
dpc-2653	296	37	table	table	NOUN
dpc-2653	296	38	5	5	NUM
dpc-2653	296	39	)	)	PUNCT
dpc-2653	296	40	.	.	PUNCT
dpc-2653	297	1	onychomadesis	onychomadesis	NOUN
dpc-2653	297	2	onychomadesis	onychomadesis	NOUN
dpc-2653	297	3	is	be	AUX
dpc-2653	297	4	a	a	DET
dpc-2653	297	5	spontaneous	spontaneous	ADJ
dpc-2653	297	6	separation	separation	NOUN
dpc-2653	297	7	of	of	ADP
dpc-2653	297	8	the	the	DET
dpc-2653	297	9	nail	nail	NOUN
dpc-2653	297	10	plate	plate	NOUN
dpc-2653	297	11	from	from	ADP
dpc-2653	297	12	the	the	DET
dpc-2653	297	13	nail	nail	NOUN
dpc-2653	297	14	bed	bed	NOUN
dpc-2653	297	15	in	in	ADP
dpc-2653	297	16	its	its	PRON
dpc-2653	297	17	proximal	proximal	ADJ
dpc-2653	297	18	portion	portion	NOUN
dpc-2653	297	19	.	.	PUNCT
dpc-2653	298	1	it	it	PRON
dpc-2653	298	2	implies	imply	VERB
dpc-2653	298	3	a	a	DET
dpc-2653	298	4	limited	limited	ADJ
dpc-2653	298	5	lesion	lesion	NOUN
dpc-2653	298	6	affecting	affect	VERB
dpc-2653	298	7	the	the	DET
dpc-2653	298	8	proximal	proximal	ADJ
dpc-2653	298	9	part	part	NOUN
dpc-2653	298	10	of	of	ADP
dpc-2653	298	11	the	the	DET
dpc-2653	298	12	matrix	matrix	NOUN
dpc-2653	298	13	.	.	PUNCT
dpc-2653	299	1	it	it	PRON
dpc-2653	299	2	results	result	VERB
dpc-2653	299	3	from	from	ADP
dpc-2653	299	4	temporary	temporary	ADJ
dpc-2653	299	5	cessation	cessation	NOUN
dpc-2653	299	6	of	of	ADP
dpc-2653	299	7	nail	nail	NOUN
dpc-2653	299	8	growth	growth	NOUN
dpc-2653	299	9	lasting	last	VERB
dpc-2653	299	10	for	for	ADP
dpc-2653	299	11	more	more	ADJ
dpc-2653	299	12	than	than	ADP
dpc-2653	299	13	2	2	NUM
dpc-2653	299	14	weeks	week	NOUN
dpc-2653	299	15	.	.	PUNCT
dpc-2653	300	1	initially	initially	ADV
dpc-2653	300	2	,	,	PUNCT
dpc-2653	300	3	a	a	DET
dpc-2653	300	4	small	small	ADJ
dpc-2653	300	5	cleavage	cleavage	NOUN
dpc-2653	300	6	appears	appear	VERB
dpc-2653	300	7	under	under	ADP
dpc-2653	300	8	the	the	DET
dpc-2653	300	9	proximal	proximal	ADJ
dpc-2653	300	10	portion	portion	NOUN
dpc-2653	300	11	of	of	ADP
dpc-2653	300	12	the	the	DET
dpc-2653	300	13	nail	nail	NOUN
dpc-2653	300	14	.	.	PUNCT
dpc-2653	301	1	this	this	PRON
dpc-2653	301	2	forms	form	VERB
dpc-2653	301	3	a	a	DET
dpc-2653	301	4	shallow	shallow	ADJ
dpc-2653	301	5	ulcer	ulcer	NOUN
dpc-2653	301	6	that	that	PRON
dpc-2653	301	7	does	do	AUX
dpc-2653	301	8	not	not	PART
dpc-2653	301	9	involve	involve	VERB
dpc-2653	301	10	the	the	DET
dpc-2653	301	11	deeper	deep	ADJ
dpc-2653	301	12	layers	layer	NOUN
dpc-2653	301	13	.	.	PUNCT
dpc-2653	302	1	when	when	SCONJ
dpc-2653	302	2	the	the	DET
dpc-2653	302	3	injury	injury	NOUN
dpc-2653	302	4	is	be	AUX
dpc-2653	302	5	healed	heal	VERB
dpc-2653	302	6	,	,	PUNCT
dpc-2653	302	7	the	the	DET
dpc-2653	302	8	nail	nail	NOUN
dpc-2653	302	9	regrows	regrow	VERB
dpc-2653	302	10	over	over	ADP
dpc-2653	302	11	again	again	ADV
dpc-2653	302	12	distally	distally	ADV
dpc-2653	302	13	.	.	PUNCT
dpc-2653	303	1	in	in	ADP
dpc-2653	303	2	latent	latent	NOUN
dpc-2653	303	3	onychomadesis	onychomadesis	NOUN
dpc-2653	303	4	,	,	PUNCT
dpc-2653	303	5	the	the	DET
dpc-2653	303	6	nail	nail	NOUN
dpc-2653	303	7	plate	plate	NOUN
dpc-2653	303	8	demonstrates	demonstrate	VERB
dpc-2653	303	9	transverse	transverse	NOUN
dpc-2653	303	10	split	split	NOUN
dpc-2653	303	11	because	because	SCONJ
dpc-2653	303	12	of	of	ADP
dpc-2653	303	13	complete	complete	ADJ
dpc-2653	303	14	inhibition	inhibition	NOUN
dpc-2653	303	15	of	of	ADP
dpc-2653	303	16	nail	nail	NOUN
dpc-2653	303	17	growth	growth	NOUN
dpc-2653	303	18	for	for	ADP
dpc-2653	303	19	1–2	1–2	NUM
dpc-2653	303	20	weeks	week	NOUN
dpc-2653	303	21	.	.	PUNCT
dpc-2653	304	1	beau	beau	PROPN
dpc-2653	304	2	’s	’s	PART
dpc-2653	304	3	lines	line	NOUN
dpc-2653	304	4	may	may	AUX
dpc-2653	304	5	evolve	evolve	VERB
dpc-2653	304	6	into	into	ADP
dpc-2653	304	7	the	the	DET
dpc-2653	304	8	formation	formation	NOUN
dpc-2653	304	9	of	of	ADP
dpc-2653	304	10	onychomadesis	onychomadesis	NOUN
dpc-2653	304	11	,	,	PUNCT
dpc-2653	304	12	which	which	PRON
dpc-2653	304	13	essentially	essentially	ADV
dpc-2653	304	14	corresponds	correspond	VERB
dpc-2653	304	15	to	to	ADP
dpc-2653	304	16	the	the	DET
dpc-2653	304	17	extreme	extreme	ADJ
dpc-2653	304	18	form	form	NOUN
dpc-2653	304	19	of	of	ADP
dpc-2653	304	20	beau	beau	PROPN
dpc-2653	304	21	’s	’s	PART
dpc-2653	304	22	lines	line	NOUN
dpc-2653	304	23	.	.	PUNCT
dpc-2653	305	1	the	the	DET
dpc-2653	305	2	nail	nail	NOUN
dpc-2653	305	3	plate	plate	NOUN
dpc-2653	305	4	is	be	AUX
dpc-2653	305	5	then	then	ADV
dpc-2653	305	6	divided	divide	VERB
dpc-2653	305	7	into	into	ADP
dpc-2653	305	8	two	two	NUM
dpc-2653	305	9	parts	part	NOUN
dpc-2653	305	10	by	by	ADP
dpc-2653	305	11	a	a	DET
dpc-2653	305	12	transverse	transverse	NOUN
dpc-2653	305	13	thick	thick	ADJ
dpc-2653	305	14	groove	groove	NOUN
dpc-2653	305	15	,	,	PUNCT
dpc-2653	305	16	which	which	PRON
dpc-2653	305	17	remains	remain	VERB
dpc-2653	305	18	latent	latent	NOUN
dpc-2653	305	19	for	for	ADP
dpc-2653	305	20	a	a	DET
dpc-2653	305	21	long	long	ADJ
dpc-2653	305	22	period	period	NOUN
dpc-2653	305	23	before	before	SCONJ
dpc-2653	305	24	the	the	DET
dpc-2653	305	25	nail	nail	NOUN
dpc-2653	305	26	plate	plate	NOUN
dpc-2653	305	27	ultimately	ultimately	ADV
dpc-2653	305	28	sheds	shed	VERB
dpc-2653	305	29	[	[	X
dpc-2653	305	30	58	58	NUM
dpc-2653	305	31	]	]	PUNCT
dpc-2653	305	32	.	.	PUNCT
dpc-2653	306	1	onychomadesis	onychomadesis	PROPN
dpc-2653	306	2	induced	induce	VERB
dpc-2653	306	3	by	by	ADP
dpc-2653	306	4	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	306	5	agents	agent	NOUN
dpc-2653	306	6	is	be	AUX
dpc-2653	306	7	thought	think	VERB
dpc-2653	306	8	to	to	PART
dpc-2653	306	9	be	be	AUX
dpc-2653	306	10	the	the	DET
dpc-2653	306	11	result	result	NOUN
dpc-2653	306	12	of	of	ADP
dpc-2653	306	13	arrested	arrest	VERB
dpc-2653	306	14	mitotic	mitotic	ADJ
dpc-2653	306	15	activity	activity	NOUN
dpc-2653	306	16	in	in	ADP
dpc-2653	306	17	the	the	DET
dpc-2653	306	18	nail	nail	NOUN
dpc-2653	306	19	matrix	matrix	NOUN
dpc-2653	306	20	resulting	result	VERB
dpc-2653	306	21	in	in	ADP
dpc-2653	306	22	nail	nail	NOUN
dpc-2653	306	23	separation	separation	NOUN
dpc-2653	306	24	and	and	CCONJ
dpc-2653	306	25	shedding	shed	VERB
dpc-2653	306	26	[	[	X
dpc-2653	306	27	59	59	NUM
dpc-2653	306	28	,	,	PUNCT
dpc-2653	306	29	60	60	NUM
dpc-2653	306	30	]	]	PUNCT
dpc-2653	306	31	.	.	PUNCT
dpc-2653	307	1	onychomadesis	onychomadesis	PROPN
dpc-2653	307	2	induced	induce	VERB
dpc-2653	307	3	by	by	ADP
dpc-2653	307	4	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	307	5	agents	agent	NOUN
dpc-2653	307	6	was	be	AUX
dpc-2653	307	7	originally	originally	ADV
dpc-2653	307	8	described	describe	VERB
dpc-2653	307	9	by	by	ADP
dpc-2653	307	10	kochupillai	kochupillai	PROPN
dpc-2653	307	11	et	et	PROPN
dpc-2653	307	12	al	al	PROPN
dpc-2653	308	1	[	[	X
dpc-2653	308	2	61	61	NUM
dpc-2653	308	3	]	]	PUNCT
dpc-2653	308	4	.	.	PUNCT
dpc-2653	309	1	since	since	SCONJ
dpc-2653	309	2	then	then	ADV
dpc-2653	309	3	only	only	ADV
dpc-2653	309	4	five	five	NUM
dpc-2653	309	5	cases	case	NOUN
dpc-2653	309	6	have	have	AUX
dpc-2653	309	7	been	be	AUX
dpc-2653	309	8	reported	report	VERB
dpc-2653	309	9	in	in	ADP
dpc-2653	309	10	the	the	DET
dpc-2653	309	11	literature	literature	NOUN
dpc-2653	309	12	.	.	PUNCT
dpc-2653	310	1	in	in	ADP
dpc-2653	310	2	saraswat	saraswat	PROPN
dpc-2653	310	3	et	et	PROPN
dpc-2653	310	4	al	al	PROPN
dpc-2653	310	5	.	.	PUNCT
dpc-2653	311	1	the	the	DET
dpc-2653	311	2	drugs	drug	NOUN
dpc-2653	311	3	associated	associate	VERB
dpc-2653	311	4	with	with	ADP
dpc-2653	311	5	the	the	DET
dpc-2653	311	6	development	development	NOUN
dpc-2653	311	7	of	of	ADP
dpc-2653	311	8	onychomadesis	onychomadesis	NOUN
dpc-2653	311	9	were	be	AUX
dpc-2653	311	10	imatinib	imatinib	NOUN
dpc-2653	311	11	,	,	PUNCT
dpc-2653	311	12	paclitaxel	paclitaxel	NOUN
dpc-2653	311	13	,	,	PUNCT
dpc-2653	311	14	capecitabine	capecitabine	NOUN
dpc-2653	311	15	,	,	PUNCT
dpc-2653	311	16	and	and	CCONJ
dpc-2653	311	17	a	a	DET
dpc-2653	311	18	combination	combination	NOUN
dpc-2653	311	19	of	of	ADP
dpc-2653	311	20	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	311	21	/	/	SYM
dpc-2653	311	22	vincristine	vincristine	NOUN
dpc-2653	311	23	/	/	SYM
dpc-2653	311	24	procarbazine/	procarbazine/	PROPN
dpc-2653	311	25	prednisolone	prednisolone	NOUN
dpc-2653	311	26	(	(	PUNCT
dpc-2653	311	27	table	table	NOUN
dpc-2653	311	28	5	5	NUM
dpc-2653	311	29	)	)	PUNCT
dpc-2653	311	30	.	.	PUNCT
dpc-2653	312	1	leukonychia	leukonychia	PROPN
dpc-2653	312	2	leukonychia	leukonychia	PROPN
dpc-2653	312	3	is	be	AUX
dpc-2653	312	4	characterized	characterize	VERB
dpc-2653	312	5	by	by	ADP
dpc-2653	312	6	white	white	ADJ
dpc-2653	312	7	discoloration	discoloration	NOUN
dpc-2653	312	8	of	of	ADP
dpc-2653	312	9	a	a	DET
dpc-2653	312	10	part	part	NOUN
dpc-2653	312	11	of	of	ADP
dpc-2653	312	12	the	the	DET
dpc-2653	312	13	nail	nail	NOUN
dpc-2653	312	14	plate	plate	NOUN
dpc-2653	312	15	or	or	CCONJ
dpc-2653	312	16	the	the	DET
dpc-2653	312	17	complete	complete	ADJ
dpc-2653	312	18	nail	nail	NOUN
dpc-2653	312	19	plate	plate	NOUN
dpc-2653	312	20	,	,	PUNCT
dpc-2653	312	21	and	and	CCONJ
dpc-2653	312	22	can	can	AUX
dpc-2653	312	23	be	be	AUX
dpc-2653	312	24	divided	divide	VERB
dpc-2653	312	25	into	into	ADP
dpc-2653	312	26	true	true	ADJ
dpc-2653	312	27	leukonychia	leukonychia	NOUN
dpc-2653	312	28	and	and	CCONJ
dpc-2653	312	29	apparent	apparent	ADJ
dpc-2653	312	30	leukonychia	leukonychia	NOUN
dpc-2653	312	31	.	.	PUNCT
dpc-2653	313	1	leukonychia	leukonychia	PROPN
dpc-2653	313	2	induced	induce	VERB
dpc-2653	313	3	by	by	ADP
dpc-2653	313	4	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	313	5	agents	agent	NOUN
dpc-2653	313	6	usually	usually	ADV
dpc-2653	313	7	occurs	occur	VERB
dpc-2653	313	8	in	in	ADP
dpc-2653	313	9	the	the	DET
dpc-2653	313	10	form	form	NOUN
dpc-2653	313	11	of	of	ADP
dpc-2653	313	12	apparent	apparent	ADJ
dpc-2653	313	13	leukonychia	leukonychia	NOUN
dpc-2653	313	14	[	[	X
dpc-2653	313	15	10	10	NUM
dpc-2653	313	16	,	,	PUNCT
dpc-2653	313	17	4648	4648	NUM
dpc-2653	313	18	,	,	PUNCT
dpc-2653	313	19	62	62	NUM
dpc-2653	313	20	]	]	PUNCT
dpc-2653	313	21	.	.	PUNCT
dpc-2653	314	1	review	review	VERB
dpc-2653	314	2	|	|	ADV
dpc-2653	314	3	dermatol	dermatol	ADJ
dpc-2653	314	4	pract	pract	NOUN
dpc-2653	314	5	concept	concept	NOUN
dpc-2653	314	6	.	.	PUNCT
dpc-2653	315	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	315	2	13	13	NUM
dpc-2653	315	3	cycles	cycle	NOUN
dpc-2653	315	4	given	give	VERB
dpc-2653	315	5	and	and	CCONJ
dpc-2653	315	6	the	the	DET
dpc-2653	315	7	cumulative	cumulative	ADJ
dpc-2653	315	8	dose	dose	NOUN
dpc-2653	315	9	of	of	ADP
dpc-2653	315	10	taxanes	taxane	NOUN
dpc-2653	315	11	[	[	X
dpc-2653	315	12	29	29	NUM
dpc-2653	315	13	,	,	PUNCT
dpc-2653	315	14	46	46	NUM
dpc-2653	315	15	,	,	PUNCT
dpc-2653	315	16	47	47	NUM
dpc-2653	315	17	,	,	PUNCT
dpc-2653	315	18	59	59	NUM
dpc-2653	315	19	]	]	PUNCT
dpc-2653	315	20	.	.	PUNCT
dpc-2653	316	1	although	although	SCONJ
dpc-2653	316	2	it	it	PRON
dpc-2653	316	3	is	be	AUX
dpc-2653	316	4	more	more	ADV
dpc-2653	316	5	common	common	ADJ
dpc-2653	316	6	in	in	ADP
dpc-2653	316	7	patients	patient	NOUN
dpc-2653	316	8	receiving	receive	VERB
dpc-2653	316	9	the	the	DET
dpc-2653	316	10	once	once	ADV
dpc-2653	316	11	-	-	PUNCT
dpc-2653	316	12	weekly	weekly	ADJ
dpc-2653	316	13	regimen	regiman	NOUN
dpc-2653	316	14	,	,	PUNCT
dpc-2653	316	15	it	it	PRON
dpc-2653	316	16	can	can	AUX
dpc-2653	316	17	also	also	ADV
dpc-2653	316	18	be	be	AUX
dpc-2653	316	19	observed	observe	VERB
dpc-2653	316	20	with	with	ADP
dpc-2653	316	21	the	the	DET
dpc-2653	316	22	every	every	DET
dpc-2653	316	23	3	3	NUM
dpc-2653	316	24	-	-	PUNCT
dpc-2653	316	25	week	week	NOUN
dpc-2653	316	26	regimen	regiman	NOUN
dpc-2653	316	27	[	[	X
dpc-2653	316	28	29	29	NUM
dpc-2653	316	29	,	,	PUNCT
dpc-2653	316	30	46	46	NUM
dpc-2653	316	31	]	]	PUNCT
dpc-2653	316	32	.	.	PUNCT
dpc-2653	317	1	the	the	DET
dpc-2653	317	2	onycholytic	onycholytic	ADJ
dpc-2653	317	3	portion	portion	NOUN
dpc-2653	317	4	of	of	ADP
dpc-2653	317	5	the	the	DET
dpc-2653	317	6	nail	nail	NOUN
dpc-2653	317	7	plate	plate	NOUN
dpc-2653	317	8	becomes	become	VERB
dpc-2653	317	9	opaque	opaque	ADJ
dpc-2653	317	10	,	,	PUNCT
dpc-2653	317	11	loses	lose	VERB
dpc-2653	317	12	its	its	PRON
dpc-2653	317	13	translucency	translucency	NOUN
dpc-2653	317	14	,	,	PUNCT
dpc-2653	317	15	and	and	CCONJ
dpc-2653	317	16	can	can	AUX
dpc-2653	317	17	take	take	VERB
dpc-2653	317	18	on	on	ADP
dpc-2653	317	19	a	a	DET
dpc-2653	317	20	white	white	ADJ
dpc-2653	317	21	,	,	PUNCT
dpc-2653	317	22	black	black	ADJ
dpc-2653	317	23	,	,	PUNCT
dpc-2653	317	24	or	or	CCONJ
dpc-2653	317	25	brown	brown	ADJ
dpc-2653	317	26	-	-	PUNCT
dpc-2653	317	27	red	red	ADJ
dpc-2653	317	28	color	color	NOUN
dpc-2653	317	29	,	,	PUNCT
dpc-2653	317	30	depending	depend	VERB
dpc-2653	317	31	on	on	ADP
dpc-2653	317	32	the	the	DET
dpc-2653	317	33	type	type	NOUN
dpc-2653	317	34	of	of	ADP
dpc-2653	317	35	lesion	lesion	NOUN
dpc-2653	317	36	[	[	X
dpc-2653	317	37	57	57	NUM
dpc-2653	317	38	,	,	PUNCT
dpc-2653	317	39	59	59	NUM
dpc-2653	317	40	,	,	PUNCT
dpc-2653	317	41	60	60	NUM
dpc-2653	317	42	]	]	PUNCT
dpc-2653	317	43	.	.	PUNCT
dpc-2653	318	1	the	the	DET
dpc-2653	318	2	fingernails	fingernail	NOUN
dpc-2653	318	3	are	be	AUX
dpc-2653	318	4	more	more	ADV
dpc-2653	318	5	often	often	ADV
dpc-2653	318	6	involved	involve	VERB
dpc-2653	318	7	than	than	ADP
dpc-2653	318	8	toenails	toenail	NOUN
dpc-2653	318	9	and	and	CCONJ
dpc-2653	318	10	the	the	DET
dpc-2653	318	11	number	number	NOUN
dpc-2653	318	12	of	of	ADP
dpc-2653	318	13	digits	digit	NOUN
dpc-2653	318	14	affected	affect	VERB
dpc-2653	318	15	varies	varie	NOUN
dpc-2653	318	16	,	,	PUNCT
dpc-2653	318	17	although	although	SCONJ
dpc-2653	318	18	involvement	involvement	NOUN
dpc-2653	318	19	may	may	AUX
dpc-2653	318	20	also	also	ADV
dpc-2653	318	21	be	be	AUX
dpc-2653	318	22	diffuse	diffuse	ADJ
dpc-2653	318	23	[	[	X
dpc-2653	318	24	29	29	NUM
dpc-2653	318	25	,	,	PUNCT
dpc-2653	318	26	59	59	NUM
dpc-2653	318	27	,	,	PUNCT
dpc-2653	318	28	6972	6972	NUM
dpc-2653	318	29	]	]	PUNCT
dpc-2653	318	30	.	.	PUNCT
dpc-2653	319	1	onycholysis	onycholysis	NOUN
dpc-2653	319	2	is	be	AUX
dpc-2653	319	3	initially	initially	ADV
dpc-2653	319	4	asymptomatic	asymptomatic	ADJ
dpc-2653	319	5	;	;	PUNCT
dpc-2653	319	6	however	however	ADV
dpc-2653	319	7	,	,	PUNCT
dpc-2653	319	8	pain	pain	NOUN
dpc-2653	319	9	may	may	AUX
dpc-2653	319	10	occur	occur	VERB
dpc-2653	319	11	due	due	ADJ
dpc-2653	319	12	to	to	ADP
dpc-2653	319	13	acute	acute	ADJ
dpc-2653	319	14	trauma	trauma	NOUN
dpc-2653	319	15	,	,	PUNCT
dpc-2653	319	16	progression	progression	NOUN
dpc-2653	319	17	of	of	ADP
dpc-2653	319	18	the	the	DET
dpc-2653	319	19	detachment	detachment	NOUN
dpc-2653	319	20	,	,	PUNCT
dpc-2653	319	21	or	or	CCONJ
dpc-2653	319	22	development	development	NOUN
dpc-2653	319	23	of	of	ADP
dpc-2653	319	24	subungual	subungual	ADJ
dpc-2653	319	25	hemorrhagic	hemorrhagic	NOUN
dpc-2653	319	26	blisters	blister	NOUN
dpc-2653	319	27	or	or	CCONJ
dpc-2653	319	28	abscesses	abscess	NOUN
dpc-2653	319	29	with	with	ADP
dpc-2653	319	30	purulent	purulent	ADJ
dpc-2653	319	31	malodorous	malodorous	ADJ
dpc-2653	319	32	discharge	discharge	NOUN
dpc-2653	319	33	(	(	PUNCT
dpc-2653	319	34	exudative	exudative	ADJ
dpc-2653	319	35	onycholysis	onycholysis	NOUN
dpc-2653	319	36	)	)	PUNCT
dpc-2653	320	1	[	[	X
dpc-2653	320	2	22	22	NUM
dpc-2653	320	3	,	,	PUNCT
dpc-2653	320	4	26	26	NUM
dpc-2653	320	5	,	,	PUNCT
dpc-2653	320	6	48	48	NUM
dpc-2653	320	7	,	,	PUNCT
dpc-2653	320	8	60	60	NUM
dpc-2653	320	9	,	,	PUNCT
dpc-2653	320	10	71	71	NUM
dpc-2653	320	11	]	]	PUNCT
dpc-2653	320	12	.	.	PUNCT
dpc-2653	321	1	secondary	secondary	ADJ
dpc-2653	321	2	bacterial	bacterial	ADJ
dpc-2653	321	3	or	or	CCONJ
dpc-2653	321	4	fungal	fungal	ADJ
dpc-2653	321	5	infections	infection	NOUN
dpc-2653	321	6	may	may	AUX
dpc-2653	321	7	also	also	ADV
dpc-2653	321	8	develop	develop	VERB
dpc-2653	321	9	because	because	SCONJ
dpc-2653	321	10	of	of	ADP
dpc-2653	321	11	the	the	DET
dpc-2653	321	12	debris	debris	NOUN
dpc-2653	321	13	collected	collect	VERB
dpc-2653	321	14	in	in	ADP
dpc-2653	321	15	the	the	DET
dpc-2653	321	16	ventral	ventral	ADJ
dpc-2653	321	17	part	part	NOUN
dpc-2653	321	18	of	of	ADP
dpc-2653	321	19	the	the	DET
dpc-2653	321	20	detached	detach	VERB
dpc-2653	321	21	plate	plate	NOUN
dpc-2653	321	22	.	.	PUNCT
dpc-2653	322	1	cosmetic	cosmetic	ADJ
dpc-2653	322	2	and	and	CCONJ
dpc-2653	322	3	functional	functional	ADJ
dpc-2653	322	4	impacts	impact	NOUN
dpc-2653	322	5	depend	depend	VERB
dpc-2653	322	6	on	on	ADP
dpc-2653	322	7	the	the	DET
dpc-2653	322	8	number	number	NOUN
dpc-2653	322	9	of	of	ADP
dpc-2653	322	10	nails	nail	NOUN
dpc-2653	322	11	involved	involve	VERB
dpc-2653	322	12	,	,	PUNCT
dpc-2653	322	13	the	the	DET
dpc-2653	322	14	severity	severity	NOUN
dpc-2653	322	15	of	of	ADP
dpc-2653	322	16	the	the	DET
dpc-2653	322	17	detachment	detachment	NOUN
dpc-2653	322	18	,	,	PUNCT
dpc-2653	322	19	and	and	CCONJ
dpc-2653	322	20	the	the	DET
dpc-2653	322	21	extent	extent	NOUN
dpc-2653	322	22	of	of	ADP
dpc-2653	322	23	pain	pain	NOUN
dpc-2653	322	24	[	[	X
dpc-2653	322	25	29	29	NUM
dpc-2653	322	26	]	]	PUNCT
dpc-2653	322	27	.	.	PUNCT
dpc-2653	323	1	taxane	taxane	NOUN
dpc-2653	323	2	-	-	PUNCT
dpc-2653	323	3	related	relate	VERB
dpc-2653	323	4	onycholysis	onycholysis	NOUN
dpc-2653	323	5	is	be	AUX
dpc-2653	323	6	sometimes	sometimes	ADV
dpc-2653	323	7	associated	associate	VERB
dpc-2653	323	8	with	with	ADP
dpc-2653	323	9	inflammatory	inflammatory	ADJ
dpc-2653	323	10	erythema	erythema	NOUN
dpc-2653	323	11	of	of	ADP
dpc-2653	323	12	dorsal	dorsal	ADJ
dpc-2653	323	13	hands	hand	NOUN
dpc-2653	323	14	or	or	CCONJ
dpc-2653	323	15	the	the	DET
dpc-2653	323	16	perimalleolar	perimalleolar	ADJ
dpc-2653	323	17	and	and	CCONJ
dpc-2653	323	18	achille	achille	PROPN
dpc-2653	323	19	’s	’s	PART
dpc-2653	323	20	areas	area	NOUN
dpc-2653	323	21	(	(	PUNCT
dpc-2653	323	22	pateo	pateo	NOUN
dpc-2653	323	23	syndrome	syndrome	NOUN
dpc-2653	323	24	:	:	PUNCT
dpc-2653	323	25	periarticular	periarticular	ADJ
dpc-2653	323	26	thenar	thenar	ADJ
dpc-2653	323	27	erythema	erythema	NOUN
dpc-2653	323	28	with	with	ADP
dpc-2653	323	29	onycholysis	onycholysis	NOUN
dpc-2653	323	30	)	)	PUNCT
dpc-2653	324	1	[	[	X
dpc-2653	324	2	22	22	NUM
dpc-2653	324	3	,	,	PUNCT
dpc-2653	324	4	24	24	NUM
dpc-2653	324	5	]	]	PUNCT
dpc-2653	324	6	.	.	PUNCT
dpc-2653	325	1	the	the	DET
dpc-2653	325	2	changes	change	NOUN
dpc-2653	325	3	may	may	AUX
dpc-2653	325	4	affect	affect	VERB
dpc-2653	325	5	both	both	PRON
dpc-2653	325	6	the	the	DET
dpc-2653	325	7	nail	nail	NOUN
dpc-2653	325	8	matrix	matrix	NOUN
dpc-2653	325	9	(	(	PUNCT
dpc-2653	325	10	melanonychia	melanonychia	PROPN
dpc-2653	325	11	,	,	PUNCT
dpc-2653	325	12	true	true	ADJ
dpc-2653	325	13	leukonychia	leukonychia	NOUN
dpc-2653	325	14	,	,	PUNCT
dpc-2653	325	15	beau	beau	PROPN
dpc-2653	325	16	’s	’s	PART
dpc-2653	325	17	lines	line	NOUN
dpc-2653	325	18	and	and	CCONJ
dpc-2653	325	19	onychomadesis	onychomadesis	NOUN
dpc-2653	325	20	,	,	PUNCT
dpc-2653	325	21	brittle	brittle	ADJ
dpc-2653	325	22	nails	nail	NOUN
dpc-2653	325	23	with	with	ADP
dpc-2653	325	24	ridging	ridging	NOUN
dpc-2653	325	25	and	and	CCONJ
dpc-2653	325	26	thinning	thinning	NOUN
dpc-2653	325	27	,	,	PUNCT
dpc-2653	325	28	onychorrhexis	onychorrhexis	ADJ
dpc-2653	325	29	,	,	PUNCT
dpc-2653	325	30	koilonychias	koilonychias	PROPN
dpc-2653	325	31	)	)	PUNCT
dpc-2653	325	32	,	,	PUNCT
dpc-2653	325	33	the	the	DET
dpc-2653	325	34	nail	nail	NOUN
dpc-2653	325	35	bed	bed	NOUN
dpc-2653	325	36	(	(	PUNCT
dpc-2653	325	37	onycholysis	onycholysis	NOUN
dpc-2653	325	38	and	and	CCONJ
dpc-2653	325	39	apparent	apparent	ADJ
dpc-2653	325	40	leukonychia	leukonychia	NOUN
dpc-2653	325	41	)	)	PUNCT
dpc-2653	325	42	or	or	CCONJ
dpc-2653	325	43	the	the	DET
dpc-2653	325	44	periungual	periungual	ADJ
dpc-2653	325	45	tissue	tissue	NOUN
dpc-2653	325	46	(	(	PUNCT
dpc-2653	325	47	paronychia	paronychia	NOUN
dpc-2653	325	48	or	or	CCONJ
dpc-2653	325	49	pyogenic	pyogenic	ADJ
dpc-2653	325	50	granuloma	granuloma	NOUN
dpc-2653	325	51	)	)	PUNCT
dpc-2653	325	52	,	,	PUNCT
dpc-2653	325	53	may	may	AUX
dpc-2653	325	54	also	also	ADV
dpc-2653	325	55	be	be	AUX
dpc-2653	325	56	affected	affect	VERB
dpc-2653	325	57	at	at	ADP
dpc-2653	325	58	the	the	DET
dpc-2653	325	59	same	same	ADJ
dpc-2653	325	60	time	time	NOUN
dpc-2653	325	61	with	with	ADP
dpc-2653	325	62	taxane	taxane	NOUN
dpc-2653	325	63	chemotherapy	chemotherapy	NOUN
dpc-2653	326	1	[	[	X
dpc-2653	326	2	22	22	NUM
dpc-2653	326	3	,	,	PUNCT
dpc-2653	326	4	24	24	NUM
dpc-2653	326	5	,	,	PUNCT
dpc-2653	326	6	26	26	NUM
dpc-2653	326	7	,	,	PUNCT
dpc-2653	326	8	47	47	NUM
dpc-2653	326	9	]	]	PUNCT
dpc-2653	326	10	.	.	PUNCT
dpc-2653	327	1	the	the	DET
dpc-2653	327	2	pathophysiological	pathophysiological	ADJ
dpc-2653	327	3	origin	origin	NOUN
dpc-2653	327	4	of	of	ADP
dpc-2653	327	5	taxane	taxane	NOUN
dpc-2653	327	6	-	-	PUNCT
dpc-2653	327	7	induced	induce	VERB
dpc-2653	327	8	onycholysis	onycholysis	NOUN
dpc-2653	327	9	is	be	AUX
dpc-2653	327	10	not	not	PART
dpc-2653	327	11	clearly	clearly	ADV
dpc-2653	327	12	established	establish	VERB
dpc-2653	327	13	.	.	PUNCT
dpc-2653	328	1	it	it	PRON
dpc-2653	328	2	may	may	AUX
dpc-2653	328	3	be	be	AUX
dpc-2653	328	4	the	the	DET
dpc-2653	328	5	result	result	NOUN
dpc-2653	328	6	of	of	ADP
dpc-2653	328	7	direct	direct	ADJ
dpc-2653	328	8	cytotoxic	cytotoxic	ADJ
dpc-2653	328	9	damage	damage	NOUN
dpc-2653	328	10	to	to	ADP
dpc-2653	328	11	the	the	DET
dpc-2653	328	12	nail	nail	NOUN
dpc-2653	328	13	matrix	matrix	NOUN
dpc-2653	328	14	and	and	CCONJ
dpc-2653	328	15	epithelial	epithelial	ADJ
dpc-2653	328	16	cells	cell	NOUN
dpc-2653	328	17	of	of	ADP
dpc-2653	328	18	the	the	DET
dpc-2653	328	19	nail	nail	NOUN
dpc-2653	328	20	bed	bed	NOUN
dpc-2653	328	21	with	with	ADP
dpc-2653	328	22	epidermolysis	epidermolysis	NOUN
dpc-2653	328	23	and	and	CCONJ
dpc-2653	328	24	the	the	DET
dpc-2653	328	25	secondary	secondary	ADJ
dpc-2653	328	26	loss	loss	NOUN
dpc-2653	328	27	of	of	ADP
dpc-2653	328	28	adhesion	adhesion	NOUN
dpc-2653	328	29	of	of	ADP
dpc-2653	328	30	the	the	DET
dpc-2653	328	31	nail	nail	NOUN
dpc-2653	328	32	plate	plate	NOUN
dpc-2653	328	33	to	to	ADP
dpc-2653	328	34	the	the	DET
dpc-2653	328	35	nail	nail	NOUN
dpc-2653	328	36	bed	bed	NOUN
dpc-2653	329	1	[	[	X
dpc-2653	329	2	24	24	NUM
dpc-2653	329	3	,	,	PUNCT
dpc-2653	329	4	47	47	NUM
dpc-2653	329	5	]	]	PUNCT
dpc-2653	329	6	.	.	PUNCT
dpc-2653	330	1	an	an	DET
dpc-2653	330	2	intrinsic	intrinsic	ADJ
dpc-2653	330	3	antiangiogenic	antiangiogenic	ADJ
dpc-2653	330	4	activity	activity	NOUN
dpc-2653	330	5	of	of	ADP
dpc-2653	330	6	taxanes	taxane	NOUN
dpc-2653	330	7	has	have	AUX
dpc-2653	330	8	also	also	ADV
dpc-2653	330	9	been	be	AUX
dpc-2653	330	10	postulated	postulate	VERB
dpc-2653	330	11	 	 	SPACE
dpc-2653	331	1	[	[	X
dpc-2653	331	2	22	22	NUM
dpc-2653	331	3	]	]	PUNCT
dpc-2653	331	4	.	.	PUNCT
dpc-2653	332	1	similarly	similarly	ADV
dpc-2653	332	2	,	,	PUNCT
dpc-2653	332	3	a	a	DET
dpc-2653	332	4	phototoxic	phototoxic	ADJ
dpc-2653	332	5	mechanism	mechanism	NOUN
dpc-2653	332	6	for	for	ADP
dpc-2653	332	7	photo	photo	NOUN
dpc-2653	332	8	-	-	PUNCT
dpc-2653	332	9	onycholysis	onycholysis	NOUN
dpc-2653	332	10	has	have	AUX
dpc-2653	332	11	been	be	AUX
dpc-2653	332	12	advanced	advance	VERB
dpc-2653	332	13	by	by	ADP
dpc-2653	332	14	some	some	DET
dpc-2653	332	15	authors	author	NOUN
dpc-2653	332	16	but	but	CCONJ
dpc-2653	332	17	remains	remain	VERB
dpc-2653	332	18	to	to	PART
dpc-2653	332	19	be	be	AUX
dpc-2653	332	20	confirmed	confirm	VERB
dpc-2653	332	21	[	[	X
dpc-2653	332	22	59	59	NUM
dpc-2653	332	23	]	]	PUNCT
dpc-2653	332	24	.	.	PUNCT
dpc-2653	333	1	lastly	lastly	ADV
dpc-2653	333	2	,	,	PUNCT
dpc-2653	333	3	unilateral	unilateral	ADJ
dpc-2653	333	4	onycholysis	onycholysis	NOUN
dpc-2653	333	5	has	have	AUX
dpc-2653	333	6	been	be	AUX
dpc-2653	333	7	reported	report	VERB
dpc-2653	333	8	in	in	ADP
dpc-2653	333	9	patients	patient	NOUN
dpc-2653	333	10	suffering	suffer	VERB
dpc-2653	333	11	from	from	ADP
dpc-2653	333	12	contralateral	contralateral	ADJ
dpc-2653	333	13	peripheral	peripheral	ADJ
dpc-2653	333	14	palsy	palsy	NOUN
dpc-2653	333	15	,	,	PUNCT
dpc-2653	333	16	suggesting	suggest	VERB
dpc-2653	333	17	a	a	DET
dpc-2653	333	18	taxane	taxane	NOUN
dpc-2653	333	19	-	-	PUNCT
dpc-2653	333	20	induced	induce	VERB
dpc-2653	333	21	neurotropic	neurotropic	ADJ
dpc-2653	333	22	effect	effect	NOUN
dpc-2653	333	23	(	(	PUNCT
dpc-2653	333	24	neurogenic	neurogenic	ADJ
dpc-2653	333	25	or	or	CCONJ
dpc-2653	333	26	prostaglandin	prostaglandin	NOUN
dpc-2653	333	27	-	-	PUNCT
dpc-2653	333	28	mediated	mediate	VERB
dpc-2653	333	29	inflammation	inflammation	NOUN
dpc-2653	333	30	)	)	PUNCT
dpc-2653	334	1	[	[	X
dpc-2653	334	2	73	73	NUM
dpc-2653	334	3	]	]	PUNCT
dpc-2653	334	4	.	.	PUNCT
dpc-2653	335	1	more	more	ADV
dpc-2653	335	2	recently	recently	ADV
dpc-2653	335	3	,	,	PUNCT
dpc-2653	335	4	schepisi	schepisi	VERB
dpc-2653	335	5	et	et	PROPN
dpc-2653	335	6	al	al	PROPN
dpc-2653	335	7	.	.	PUNCT
dpc-2653	336	1	[	[	X
dpc-2653	336	2	34	34	NUM
dpc-2653	336	3	]	]	PUNCT
dpc-2653	336	4	hypothesized	hypothesize	VERB
dpc-2653	336	5	that	that	SCONJ
dpc-2653	336	6	paclitaxel	paclitaxel	NOUN
dpc-2653	336	7	-	-	PUNCT
dpc-2653	336	8	related	relate	VERB
dpc-2653	336	9	onycholysis	onycholysis	NOUN
dpc-2653	336	10	may	may	AUX
dpc-2653	336	11	be	be	AUX
dpc-2653	336	12	directly	directly	ADV
dpc-2653	336	13	correlated	correlate	VERB
dpc-2653	336	14	to	to	ADP
dpc-2653	336	15	the	the	DET
dpc-2653	336	16	duration	duration	NOUN
dpc-2653	336	17	of	of	ADP
dpc-2653	336	18	the	the	DET
dpc-2653	336	19	infusion	infusion	NOUN
dpc-2653	336	20	.	.	PUNCT
dpc-2653	337	1	indeed	indeed	ADV
dpc-2653	337	2	,	,	PUNCT
dpc-2653	337	3	onycholysis	onycholysis	NOUN
dpc-2653	337	4	may	may	AUX
dpc-2653	337	5	develop	develop	VERB
dpc-2653	337	6	more	more	ADV
dpc-2653	337	7	frequently	frequently	ADV
dpc-2653	337	8	with	with	ADP
dpc-2653	337	9	a	a	DET
dpc-2653	337	10	shorter	short	ADJ
dpc-2653	337	11	infusion	infusion	NOUN
dpc-2653	337	12	(	(	PUNCT
dpc-2653	337	13	1	1	NUM
dpc-2653	337	14	hour	hour	NOUN
dpc-2653	337	15	)	)	PUNCT
dpc-2653	337	16	than	than	ADP
dpc-2653	337	17	with	with	ADP
dpc-2653	337	18	a	a	DET
dpc-2653	337	19	prolonged	prolonged	ADJ
dpc-2653	337	20	infusion	infusion	NOUN
dpc-2653	337	21	,	,	PUNCT
dpc-2653	337	22	because	because	SCONJ
dpc-2653	337	23	of	of	ADP
dpc-2653	337	24	increased	increase	VERB
dpc-2653	337	25	systemic	systemic	ADJ
dpc-2653	337	26	exposure	exposure	NOUN
dpc-2653	337	27	to	to	ADP
dpc-2653	337	28	the	the	DET
dpc-2653	337	29	cremophor	cremophor	NOUN
dpc-2653	337	30	vehicle	vehicle	NOUN
dpc-2653	337	31	(	(	PUNCT
dpc-2653	337	32	paclitaxel	paclitaxel	PROPN
dpc-2653	337	33	solvent	solvent	NOUN
dpc-2653	337	34	)	)	PUNCT
dpc-2653	337	35	.	.	PUNCT
dpc-2653	338	1	that	that	PRON
dpc-2653	338	2	may	may	AUX
dpc-2653	338	3	explain	explain	VERB
dpc-2653	338	4	,	,	PUNCT
dpc-2653	338	5	at	at	ADP
dpc-2653	338	6	least	least	ADJ
dpc-2653	338	7	in	in	ADP
dpc-2653	338	8	part	part	NOUN
dpc-2653	338	9	,	,	PUNCT
dpc-2653	338	10	the	the	DET
dpc-2653	338	11	higher	high	ADJ
dpc-2653	338	12	incidence	incidence	NOUN
dpc-2653	338	13	seen	see	VERB
dpc-2653	338	14	in	in	ADP
dpc-2653	338	15	patients	patient	NOUN
dpc-2653	338	16	receiving	receive	VERB
dpc-2653	338	17	the	the	DET
dpc-2653	338	18	weekly	weekly	ADJ
dpc-2653	338	19	paclitaxel	paclitaxel	ADJ
dpc-2653	338	20	regimen	regiman	NOUN
dpc-2653	338	21	(	(	PUNCT
dpc-2653	338	22	1	1	NUM
dpc-2653	338	23	-	-	PUNCT
dpc-2653	338	24	hour	hour	NOUN
dpc-2653	338	25	infusion	infusion	NOUN
dpc-2653	338	26	)	)	PUNCT
dpc-2653	338	27	in	in	ADP
dpc-2653	338	28	comparison	comparison	NOUN
dpc-2653	338	29	with	with	ADP
dpc-2653	338	30	the	the	DET
dpc-2653	338	31	every	every	DET
dpc-2653	338	32	3	3	NUM
dpc-2653	338	33	-	-	PUNCT
dpc-2653	338	34	week	week	NOUN
dpc-2653	338	35	regimen	regiman	NOUN
dpc-2653	338	36	(	(	PUNCT
dpc-2653	338	37	3	3	NUM
dpc-2653	338	38	-	-	PUNCT
dpc-2653	338	39	hour	hour	NOUN
dpc-2653	338	40	infusion	infusion	NOUN
dpc-2653	338	41	)	)	PUNCT
dpc-2653	338	42	.	.	PUNCT
dpc-2653	339	1	generally	generally	ADV
dpc-2653	339	2	develops	develop	VERB
dpc-2653	339	3	when	when	SCONJ
dpc-2653	339	4	chemotherapy	chemotherapy	NOUN
dpc-2653	339	5	is	be	AUX
dpc-2653	339	6	used	use	VERB
dpc-2653	339	7	in	in	ADP
dpc-2653	339	8	combination	combination	NOUN
dpc-2653	339	9	.	.	PUNCT
dpc-2653	340	1	systematic	systematic	ADJ
dpc-2653	340	2	screening	screening	NOUN
dpc-2653	340	3	for	for	ADP
dpc-2653	340	4	associated	associate	VERB
dpc-2653	340	5	hypoalbuminemia	hypoalbuminemia	NOUN
dpc-2653	340	6	should	should	AUX
dpc-2653	340	7	be	be	AUX
dpc-2653	340	8	performed	perform	VERB
dpc-2653	340	9	in	in	ADP
dpc-2653	340	10	this	this	DET
dpc-2653	340	11	context	context	NOUN
dpc-2653	340	12	.	.	PUNCT
dpc-2653	341	1	mees	mees	PROPN
dpc-2653	341	2	’	'	PUNCT
dpc-2653	341	3	lines	line	NOUN
dpc-2653	341	4	are	be	AUX
dpc-2653	341	5	usually	usually	ADV
dpc-2653	341	6	observed	observe	VERB
dpc-2653	341	7	with	with	ADP
dpc-2653	341	8	the	the	DET
dpc-2653	341	9	use	use	NOUN
dpc-2653	341	10	of	of	ADP
dpc-2653	341	11	docetaxel	docetaxel	NOUN
dpc-2653	341	12	and	and	CCONJ
dpc-2653	341	13	a	a	DET
dpc-2653	341	14	combination	combination	NOUN
dpc-2653	341	15	of	of	ADP
dpc-2653	341	16	cytarabine	cytarabine	NOUN
dpc-2653	341	17	/	/	SYM
dpc-2653	341	18	daunorubicin	daunorubicin	PROPN
dpc-2653	341	19	and	and	CCONJ
dpc-2653	341	20	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	341	21	/	/	SYM
dpc-2653	341	22	doxorubicin	doxorubicin	PROPN
dpc-2653	341	23	/	/	SYM
dpc-2653	341	24	vincristine	vincristine	NOUN
dpc-2653	341	25	/	/	SYM
dpc-2653	341	26	prednisolone	prednisolone	PROPN
dpc-2653	342	1	[	[	X
dpc-2653	342	2	6567	6567	NUM
dpc-2653	342	3	]	]	PUNCT
dpc-2653	342	4	(	(	PUNCT
dpc-2653	342	5	table	table	NOUN
dpc-2653	342	6	5	5	NUM
dpc-2653	342	7	)	)	PUNCT
dpc-2653	342	8	.	.	PUNCT
dpc-2653	343	1	muehrcke	muehrcke	PROPN
dpc-2653	343	2	’s	’s	PART
dpc-2653	343	3	lines	line	NOUN
dpc-2653	343	4	have	have	AUX
dpc-2653	343	5	been	be	AUX
dpc-2653	343	6	reported	report	VERB
dpc-2653	343	7	with	with	ADP
dpc-2653	343	8	cisplatin	cisplatin	NOUN
dpc-2653	343	9	,	,	PUNCT
dpc-2653	343	10	oxaliplatin	oxaliplatin	NOUN
dpc-2653	343	11	and	and	CCONJ
dpc-2653	343	12	a	a	DET
dpc-2653	343	13	combination	combination	NOUN
dpc-2653	343	14	of	of	ADP
dpc-2653	343	15	cyclophosphamide/	cyclophosphamide/	NUM
dpc-2653	343	16	doxorubicin/5	doxorubicin/5	NOUN
dpc-2653	343	17	-	-	PUNCT
dpc-2653	343	18	fluorouracil	fluorouracil	NOUN
dpc-2653	343	19	and	and	CCONJ
dpc-2653	343	20	vincristine	vincristine	NOUN
dpc-2653	343	21	/	/	SYM
dpc-2653	343	22	doxorubicin/	doxorubicin/	VERB
dpc-2653	343	23	dexamethasone	dexamethasone	NOUN
dpc-2653	344	1	[	[	X
dpc-2653	344	2	68	68	NUM
dpc-2653	344	3	]	]	PUNCT
dpc-2653	344	4	(	(	PUNCT
dpc-2653	344	5	table	table	NOUN
dpc-2653	344	6	5	5	NUM
dpc-2653	344	7	)	)	PUNCT
dpc-2653	344	8	.	.	PUNCT
dpc-2653	345	1	nail	nail	NOUN
dpc-2653	345	2	growth	growth	NOUN
dpc-2653	345	3	is	be	AUX
dpc-2653	345	4	faster	fast	ADJ
dpc-2653	345	5	in	in	ADP
dpc-2653	345	6	children	child	NOUN
dpc-2653	345	7	and	and	CCONJ
dpc-2653	345	8	adolescents	adolescent	NOUN
dpc-2653	345	9	,	,	PUNCT
dpc-2653	345	10	and	and	CCONJ
dpc-2653	345	11	is	be	AUX
dpc-2653	345	12	estimated	estimate	VERB
dpc-2653	345	13	to	to	PART
dpc-2653	345	14	be	be	AUX
dpc-2653	345	15	at	at	ADP
dpc-2653	345	16	a	a	DET
dpc-2653	345	17	rate	rate	NOUN
dpc-2653	345	18	of	of	ADP
dpc-2653	345	19	0.12	0.12	NUM
dpc-2653	345	20	mm	mm	NOUN
dpc-2653	345	21	/	/	SYM
dpc-2653	345	22	day	day	NOUN
dpc-2653	345	23	[	[	X
dpc-2653	345	24	23	23	NUM
dpc-2653	345	25	]	]	PUNCT
dpc-2653	345	26	.	.	PUNCT
dpc-2653	346	1	however	however	ADV
dpc-2653	346	2	,	,	PUNCT
dpc-2653	346	3	chemotherapy	chemotherapy	NOUN
dpc-2653	346	4	-	-	ADJ
dpc-2653	346	5	induced	induce	VERB
dpc-2653	346	6	nail	nail	NOUN
dpc-2653	346	7	changes	change	NOUN
dpc-2653	346	8	in	in	ADP
dpc-2653	346	9	children	child	NOUN
dpc-2653	346	10	,	,	PUNCT
dpc-2653	346	11	in	in	ADP
dpc-2653	346	12	comparison	comparison	NOUN
dpc-2653	346	13	to	to	ADP
dpc-2653	346	14	adult	adult	NOUN
dpc-2653	346	15	cases	case	NOUN
dpc-2653	346	16	,	,	PUNCT
dpc-2653	346	17	are	be	AUX
dpc-2653	346	18	less	less	ADV
dpc-2653	346	19	well	well	ADV
dpc-2653	346	20	characterized	characterize	VERB
dpc-2653	346	21	in	in	ADP
dpc-2653	346	22	the	the	DET
dpc-2653	346	23	literature	literature	NOUN
dpc-2653	346	24	.	.	PUNCT
dpc-2653	347	1	reviewing	review	VERB
dpc-2653	347	2	the	the	DET
dpc-2653	347	3	limited	limited	ADJ
dpc-2653	347	4	case	case	NOUN
dpc-2653	347	5	reports	report	VERB
dpc-2653	347	6	,	,	PUNCT
dpc-2653	347	7	transverse	transverse	NOUN
dpc-2653	347	8	leukonychia	leukonychia	NOUN
dpc-2653	347	9	seems	seem	VERB
dpc-2653	347	10	to	to	PART
dpc-2653	347	11	be	be	AUX
dpc-2653	347	12	the	the	DET
dpc-2653	347	13	most	most	ADV
dpc-2653	347	14	frequently	frequently	ADV
dpc-2653	347	15	described	describe	VERB
dpc-2653	347	16	nail	nail	NOUN
dpc-2653	347	17	change	change	NOUN
dpc-2653	347	18	in	in	ADP
dpc-2653	347	19	children	child	NOUN
dpc-2653	347	20	receiving	receive	VERB
dpc-2653	347	21	chemotherapy	chemotherapy	NOUN
dpc-2653	347	22	,	,	PUNCT
dpc-2653	347	23	with	with	ADP
dpc-2653	347	24	doxorubicin	doxorubicin	PROPN
dpc-2653	347	25	/	/	SYM
dpc-2653	347	26	daunorubicin	daunorubicin	PROPN
dpc-2653	347	27	,	,	PUNCT
dpc-2653	347	28	vincristine	vincristine	NOUN
dpc-2653	347	29	and	and	CCONJ
dpc-2653	347	30	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	347	31	being	be	AUX
dpc-2653	347	32	the	the	DET
dpc-2653	347	33	main	main	ADJ
dpc-2653	347	34	causative	causative	ADJ
dpc-2653	347	35	agents	agent	NOUN
dpc-2653	347	36	[	[	X
dpc-2653	347	37	23	23	NUM
dpc-2653	347	38	,	,	PUNCT
dpc-2653	347	39	66	66	NUM
dpc-2653	347	40	]	]	PUNCT
dpc-2653	347	41	.	.	PUNCT
dpc-2653	348	1	onycholysis	onycholysis	NOUN
dpc-2653	348	2	onycholysis	onycholysis	NOUN
dpc-2653	348	3	is	be	AUX
dpc-2653	348	4	defined	define	VERB
dpc-2653	348	5	by	by	ADP
dpc-2653	348	6	the	the	DET
dpc-2653	348	7	separation	separation	NOUN
dpc-2653	348	8	of	of	ADP
dpc-2653	348	9	the	the	DET
dpc-2653	348	10	nail	nail	NOUN
dpc-2653	348	11	plate	plate	NOUN
dpc-2653	348	12	from	from	ADP
dpc-2653	348	13	the	the	DET
dpc-2653	348	14	underlying	underlie	VERB
dpc-2653	348	15	nail	nail	NOUN
dpc-2653	348	16	bed	bed	NOUN
dpc-2653	349	1	[	[	X
dpc-2653	349	2	48	48	NUM
dpc-2653	349	3	]	]	PUNCT
dpc-2653	349	4	.	.	PUNCT
dpc-2653	350	1	it	it	PRON
dpc-2653	350	2	usually	usually	ADV
dpc-2653	350	3	starts	start	VERB
dpc-2653	350	4	from	from	ADP
dpc-2653	350	5	the	the	DET
dpc-2653	350	6	distal	distal	ADJ
dpc-2653	350	7	portion	portion	NOUN
dpc-2653	350	8	of	of	ADP
dpc-2653	350	9	the	the	DET
dpc-2653	350	10	nail	nail	NOUN
dpc-2653	350	11	bed	bed	NOUN
dpc-2653	350	12	,	,	PUNCT
dpc-2653	350	13	progresses	progress	VERB
dpc-2653	350	14	proximally	proximally	ADV
dpc-2653	350	15	,	,	PUNCT
dpc-2653	350	16	and	and	CCONJ
dpc-2653	350	17	can	can	AUX
dpc-2653	350	18	involve	involve	VERB
dpc-2653	350	19	the	the	DET
dpc-2653	350	20	entire	entire	ADJ
dpc-2653	350	21	nail	nail	NOUN
dpc-2653	350	22	with	with	ADP
dpc-2653	350	23	the	the	DET
dpc-2653	350	24	formation	formation	NOUN
dpc-2653	350	25	of	of	ADP
dpc-2653	350	26	a	a	DET
dpc-2653	350	27	space	space	NOUN
dpc-2653	350	28	.	.	PUNCT
dpc-2653	351	1	this	this	PRON
dpc-2653	351	2	may	may	AUX
dpc-2653	351	3	result	result	VERB
dpc-2653	351	4	in	in	ADP
dpc-2653	351	5	the	the	DET
dpc-2653	351	6	formation	formation	NOUN
dpc-2653	351	7	of	of	ADP
dpc-2653	351	8	painful	painful	ADJ
dpc-2653	351	9	subungual	subungual	ADJ
dpc-2653	351	10	abscesses	abscess	NOUN
dpc-2653	351	11	and	and	CCONJ
dpc-2653	351	12	hemorrhages	hemorrhage	NOUN
dpc-2653	351	13	and	and	CCONJ
dpc-2653	351	14	finally	finally	ADV
dpc-2653	351	15	loss	loss	NOUN
dpc-2653	351	16	of	of	ADP
dpc-2653	351	17	the	the	DET
dpc-2653	351	18	nail	nail	NOUN
dpc-2653	351	19	plate	plate	NOUN
dpc-2653	351	20	.	.	PUNCT
dpc-2653	352	1	it	it	PRON
dpc-2653	352	2	is	be	AUX
dpc-2653	352	3	noteworthy	noteworthy	ADJ
dpc-2653	352	4	that	that	SCONJ
dpc-2653	352	5	the	the	DET
dpc-2653	352	6	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	352	7	agents	agent	NOUN
dpc-2653	352	8	that	that	PRON
dpc-2653	352	9	most	most	ADV
dpc-2653	352	10	frequently	frequently	ADV
dpc-2653	352	11	induce	induce	VERB
dpc-2653	352	12	nail	nail	NOUN
dpc-2653	352	13	changes	change	NOUN
dpc-2653	352	14	are	be	AUX
dpc-2653	352	15	taxanes	taxane	NOUN
dpc-2653	352	16	:	:	PUNCT
dpc-2653	352	17	docetaxel	docetaxel	NOUN
dpc-2653	352	18	and	and	CCONJ
dpc-2653	352	19	paclitaxel	paclitaxel	PROPN
dpc-2653	352	20	,	,	PUNCT
dpc-2653	352	21	resulting	result	VERB
dpc-2653	352	22	from	from	ADP
dpc-2653	352	23	a	a	DET
dpc-2653	352	24	direct	direct	ADJ
dpc-2653	352	25	toxic	toxic	ADJ
dpc-2653	352	26	effect	effect	NOUN
dpc-2653	352	27	[	[	X
dpc-2653	352	28	22	22	NUM
dpc-2653	352	29	,	,	PUNCT
dpc-2653	352	30	25	25	NUM
dpc-2653	352	31	,	,	PUNCT
dpc-2653	352	32	26	26	NUM
dpc-2653	352	33	,	,	PUNCT
dpc-2653	352	34	 	 	SPACE
dpc-2653	352	35	46	46	NUM
dpc-2653	352	36	,	,	PUNCT
dpc-2653	352	37	59	59	NUM
dpc-2653	352	38	]	]	PUNCT
dpc-2653	352	39	.	.	PUNCT
dpc-2653	353	1	however	however	ADV
dpc-2653	353	2	,	,	PUNCT
dpc-2653	353	3	mild	mild	ADJ
dpc-2653	353	4	to	to	ADP
dpc-2653	353	5	moderate	moderate	ADJ
dpc-2653	353	6	onycholysis	onycholysis	NOUN
dpc-2653	353	7	may	may	AUX
dpc-2653	353	8	also	also	ADV
dpc-2653	353	9	be	be	AUX
dpc-2653	353	10	noted	note	VERB
dpc-2653	353	11	with	with	ADP
dpc-2653	353	12	other	other	ADJ
dpc-2653	353	13	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	353	14	agents	agent	NOUN
dpc-2653	353	15	as	as	ADV
dpc-2653	353	16	well	well	ADV
dpc-2653	353	17	(	(	PUNCT
dpc-2653	353	18	capecitabine	capecitabine	NOUN
dpc-2653	353	19	,	,	PUNCT
dpc-2653	353	20	etoposide	etoposide	NOUN
dpc-2653	353	21	,	,	PUNCT
dpc-2653	353	22	cytarabine	cytarabine	NOUN
dpc-2653	353	23	,	,	PUNCT
dpc-2653	353	24	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	353	25	,	,	PUNCT
dpc-2653	353	26	doxorubicin	doxorubicin	PROPN
dpc-2653	353	27	,	,	PUNCT
dpc-2653	353	28	or	or	CCONJ
dpc-2653	353	29	combination	combination	NOUN
dpc-2653	353	30	therapy	therapy	NOUN
dpc-2653	353	31	)	)	PUNCT
dpc-2653	354	1	[	[	X
dpc-2653	354	2	24	24	NUM
dpc-2653	354	3	,	,	PUNCT
dpc-2653	354	4	46	46	NUM
dpc-2653	354	5	,	,	PUNCT
dpc-2653	354	6	48	48	NUM
dpc-2653	354	7	]	]	PUNCT
dpc-2653	354	8	.	.	PUNCT
dpc-2653	355	1	the	the	DET
dpc-2653	355	2	targeted	target	VERB
dpc-2653	355	3	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	355	4	agents	agent	NOUN
dpc-2653	355	5	,	,	PUNCT
dpc-2653	355	6	which	which	PRON
dpc-2653	355	7	may	may	AUX
dpc-2653	355	8	cause	cause	VERB
dpc-2653	355	9	onycholysis	onycholysis	NOUN
dpc-2653	355	10	are	be	AUX
dpc-2653	355	11	cetuximab	cetuximab	NOUN
dpc-2653	355	12	,	,	PUNCT
dpc-2653	355	13	panitumumab	panitumumab	NOUN
dpc-2653	355	14	,	,	PUNCT
dpc-2653	355	15	erlotinib	erlotinib	NOUN
dpc-2653	355	16	,	,	PUNCT
dpc-2653	355	17	gefitinib	gefitinib	NOUN
dpc-2653	355	18	,	,	PUNCT
dpc-2653	355	19	necitumumab	necitumumab	NOUN
dpc-2653	355	20	,	,	PUNCT
dpc-2653	355	21	lapatinib	lapatinib	PROPN
dpc-2653	355	22	,	,	PUNCT
dpc-2653	355	23	afatinib	afatinib	NOUN
dpc-2653	355	24	,	,	PUNCT
dpc-2653	355	25	dacomitinib	dacomitinib	NOUN
dpc-2653	355	26	,	,	PUNCT
dpc-2653	355	27	trametinib	trametinib	NOUN
dpc-2653	355	28	,	,	PUNCT
dpc-2653	355	29	cobimetinib	cobimetinib	NOUN
dpc-2653	355	30	,	,	PUNCT
dpc-2653	355	31	selumetinib	selumetinib	NOUN
dpc-2653	355	32	,	,	PUNCT
dpc-2653	355	33	everolimus	everolimus	ADJ
dpc-2653	355	34	,	,	PUNCT
dpc-2653	355	35	temsirolimus	temsirolimus	NOUN
dpc-2653	355	36	,	,	PUNCT
dpc-2653	355	37	ibrutinib	ibrutinib	NOUN
dpc-2653	355	38	and	and	CCONJ
dpc-2653	355	39	vandetanib	vandetanib	NOUN
dpc-2653	355	40	[	[	X
dpc-2653	355	41	38	38	NUM
dpc-2653	355	42	]	]	PUNCT
dpc-2653	355	43	(	(	PUNCT
dpc-2653	355	44	table	table	NOUN
dpc-2653	355	45	5	5	NUM
dpc-2653	355	46	)	)	PUNCT
dpc-2653	355	47	.	.	PUNCT
dpc-2653	356	1	onycholysis	onycholysis	NOUN
dpc-2653	356	2	is	be	AUX
dpc-2653	356	3	one	one	NUM
dpc-2653	356	4	of	of	ADP
dpc-2653	356	5	the	the	DET
dpc-2653	356	6	most	most	ADV
dpc-2653	356	7	prevalent	prevalent	ADJ
dpc-2653	356	8	adverse	adverse	ADJ
dpc-2653	356	9	events	event	NOUN
dpc-2653	356	10	induced	induce	VERB
dpc-2653	356	11	by	by	ADP
dpc-2653	356	12	docetaxel	docetaxel	NOUN
dpc-2653	356	13	or	or	CCONJ
dpc-2653	356	14	paclitaxel	paclitaxel	PROPN
dpc-2653	356	15	[	[	X
dpc-2653	356	16	22	22	NUM
dpc-2653	356	17	]	]	PUNCT
dpc-2653	356	18	.	.	PUNCT
dpc-2653	357	1	recently	recently	ADV
dpc-2653	357	2	,	,	PUNCT
dpc-2653	357	3	the	the	DET
dpc-2653	357	4	overall	overall	ADJ
dpc-2653	357	5	incidence	incidence	NOUN
dpc-2653	357	6	of	of	ADP
dpc-2653	357	7	taxane	taxane	NOUN
dpc-2653	357	8	-	-	PUNCT
dpc-2653	357	9	induced	induce	VERB
dpc-2653	357	10	nail	nail	NOUN
dpc-2653	357	11	toxicity	toxicity	NOUN
dpc-2653	357	12	has	have	AUX
dpc-2653	357	13	been	be	AUX
dpc-2653	357	14	systematically	systematically	ADV
dpc-2653	357	15	investigated	investigate	VERB
dpc-2653	357	16	[	[	X
dpc-2653	357	17	35	35	NUM
dpc-2653	357	18	]	]	X
dpc-2653	357	19	;	;	PUNCT
dpc-2653	357	20	all	all	DET
dpc-2653	357	21	-	-	PUNCT
dpc-2653	357	22	grade	grade	NOUN
dpc-2653	357	23	incidence	incidence	NOUN
dpc-2653	357	24	was	be	AUX
dpc-2653	357	25	43.7	43.7	NUM
dpc-2653	357	26	%	%	NOUN
dpc-2653	357	27	with	with	ADP
dpc-2653	357	28	paclitaxel	paclitaxel	PROPN
dpc-2653	357	29	(	(	PUNCT
dpc-2653	357	30	95	95	NUM
dpc-2653	357	31	%	%	NOUN
dpc-2653	357	32	ci	ci	NOUN
dpc-2653	357	33	:	:	PUNCT
dpc-2653	357	34	18.0	18.0	NUM
dpc-2653	357	35	-	-	SYM
dpc-2653	357	36	73.3	73.3	NUM
dpc-2653	357	37	%	%	NOUN
dpc-2653	357	38	)	)	PUNCT
dpc-2653	357	39	and	and	CCONJ
dpc-2653	357	40	34.9	34.9	NUM
dpc-2653	357	41	%	%	NOUN
dpc-2653	357	42	(	(	PUNCT
dpc-2653	357	43	95	95	NUM
dpc-2653	357	44	%	%	NOUN
dpc-2653	357	45	ci	ci	NOUN
dpc-2653	357	46	:	:	PUNCT
dpc-2653	357	47	29.9	29.9	NUM
dpc-2653	357	48	-	-	SYM
dpc-2653	357	49	40.2	40.2	NUM
dpc-2653	357	50	%	%	NOUN
dpc-2653	357	51	)	)	PUNCT
dpc-2653	357	52	with	with	ADP
dpc-2653	357	53	docetaxel	docetaxel	PROPN
dpc-2653	357	54	.	.	PUNCT
dpc-2653	358	1	for	for	ADP
dpc-2653	358	2	the	the	DET
dpc-2653	358	3	latter	latter	ADJ
dpc-2653	358	4	,	,	PUNCT
dpc-2653	358	5	the	the	DET
dpc-2653	358	6	relative	relative	ADJ
dpc-2653	358	7	risk	risk	NOUN
dpc-2653	358	8	was	be	AUX
dpc-2653	358	9	77.74	77.74	NUM
dpc-2653	358	10	(	(	PUNCT
dpc-2653	358	11	95	95	NUM
dpc-2653	358	12	%	%	NOUN
dpc-2653	358	13	ci	ci	NOUN
dpc-2653	358	14	:	:	PUNCT
dpc-2653	358	15	41.88	41.88	NUM
dpc-2653	358	16	-	-	SYM
dpc-2653	358	17	144.32	144.32	NUM
dpc-2653	358	18	;	;	PUNCT
dpc-2653	358	19	p<0.001	p<0.001	X
dpc-2653	358	20	)	)	PUNCT
dpc-2653	358	21	as	as	SCONJ
dpc-2653	358	22	compared	compare	VERB
dpc-2653	358	23	to	to	ADP
dpc-2653	358	24	controls	control	NOUN
dpc-2653	358	25	[	[	X
dpc-2653	358	26	22	22	NUM
dpc-2653	358	27	]	]	PUNCT
dpc-2653	358	28	.	.	PUNCT
dpc-2653	359	1	nail	nail	NOUN
dpc-2653	359	2	changes	change	NOUN
dpc-2653	359	3	are	be	AUX
dpc-2653	359	4	evident	evident	ADJ
dpc-2653	359	5	after	after	ADP
dpc-2653	359	6	several	several	ADJ
dpc-2653	359	7	weeks	week	NOUN
dpc-2653	359	8	of	of	ADP
dpc-2653	359	9	treatment	treatment	NOUN
dpc-2653	359	10	because	because	SCONJ
dpc-2653	359	11	of	of	ADP
dpc-2653	359	12	the	the	DET
dpc-2653	359	13	slow	slow	ADJ
dpc-2653	359	14	growth	growth	NOUN
dpc-2653	359	15	rate	rate	NOUN
dpc-2653	359	16	of	of	ADP
dpc-2653	359	17	the	the	DET
dpc-2653	359	18	nail	nail	NOUN
dpc-2653	359	19	plate	plate	NOUN
dpc-2653	359	20	[	[	X
dpc-2653	359	21	29	29	NUM
dpc-2653	359	22	]	]	PUNCT
dpc-2653	359	23	.	.	PUNCT
dpc-2653	360	1	the	the	DET
dpc-2653	360	2	development	development	NOUN
dpc-2653	360	3	of	of	ADP
dpc-2653	360	4	nail	nail	NOUN
dpc-2653	360	5	changes	change	NOUN
dpc-2653	360	6	is	be	AUX
dpc-2653	360	7	strongly	strongly	ADV
dpc-2653	360	8	associated	associate	VERB
dpc-2653	360	9	with	with	ADP
dpc-2653	360	10	weekly	weekly	ADJ
dpc-2653	360	11	administration	administration	NOUN
dpc-2653	360	12	,	,	PUNCT
dpc-2653	360	13	the	the	DET
dpc-2653	360	14	number	number	NOUN
dpc-2653	360	15	of	of	ADP
dpc-2653	360	16	chemotherapy	chemotherapy	NOUN
dpc-2653	360	17	14	14	NUM
dpc-2653	360	18	review	review	NOUN
dpc-2653	360	19	|	|	ADV
dpc-2653	360	20	dermatol	dermatol	ADJ
dpc-2653	360	21	pract	pract	NOUN
dpc-2653	360	22	concept	concept	NOUN
dpc-2653	360	23	.	.	PUNCT
dpc-2653	361	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	361	2	onychorrhexis	onychorrhexis	NOUN
dpc-2653	361	3	is	be	AUX
dpc-2653	361	4	a	a	DET
dpc-2653	361	5	type	type	NOUN
dpc-2653	361	6	of	of	ADP
dpc-2653	361	7	longitudinal	longitudinal	ADJ
dpc-2653	361	8	groove	groove	NOUN
dpc-2653	361	9	wherein	wherein	SCONJ
dpc-2653	361	10	a	a	DET
dpc-2653	361	11	series	series	NOUN
dpc-2653	361	12	of	of	ADP
dpc-2653	361	13	shallow	shallow	ADJ
dpc-2653	361	14	and	and	CCONJ
dpc-2653	361	15	narrow	narrow	ADJ
dpc-2653	361	16	furrows	furrow	NOUN
dpc-2653	361	17	are	be	AUX
dpc-2653	361	18	present	present	ADJ
dpc-2653	361	19	running	run	VERB
dpc-2653	361	20	parallel	parallel	NOUN
dpc-2653	361	21	on	on	ADP
dpc-2653	361	22	the	the	DET
dpc-2653	361	23	nail	nail	NOUN
dpc-2653	361	24	surface	surface	NOUN
dpc-2653	361	25	.	.	PUNCT
dpc-2653	362	1	docetaxel	docetaxel	PROPN
dpc-2653	362	2	,	,	PUNCT
dpc-2653	362	3	paclitaxel	paclitaxel	PROPN
dpc-2653	362	4	and	and	CCONJ
dpc-2653	362	5	ibrutinib	ibrutinib	NOUN
dpc-2653	362	6	may	may	AUX
dpc-2653	362	7	cause	cause	VERB
dpc-2653	362	8	onychorrhexis	onychorrhexis	NOUN
dpc-2653	362	9	(	(	PUNCT
dpc-2653	362	10	table	table	NOUN
dpc-2653	362	11	5	5	NUM
dpc-2653	362	12	)	)	PUNCT
dpc-2653	362	13	.	.	PUNCT
dpc-2653	363	1	onychoschizia	onychoschizia	PROPN
dpc-2653	363	2	is	be	AUX
dpc-2653	363	3	clinically	clinically	ADV
dpc-2653	363	4	characterized	characterize	VERB
dpc-2653	363	5	by	by	ADP
dpc-2653	363	6	the	the	DET
dpc-2653	363	7	splitting	splitting	NOUN
dpc-2653	363	8	of	of	ADP
dpc-2653	363	9	the	the	DET
dpc-2653	363	10	nail	nail	NOUN
dpc-2653	363	11	plate	plate	NOUN
dpc-2653	363	12	at	at	ADP
dpc-2653	363	13	the	the	DET
dpc-2653	363	14	free	free	ADJ
dpc-2653	363	15	edges	edge	NOUN
dpc-2653	363	16	in	in	ADP
dpc-2653	363	17	the	the	DET
dpc-2653	363	18	fingers	finger	NOUN
dpc-2653	363	19	and	and	CCONJ
dpc-2653	363	20	toes	toe	NOUN
dpc-2653	363	21	.	.	PUNCT
dpc-2653	364	1	it	it	PRON
dpc-2653	364	2	may	may	AUX
dpc-2653	364	3	be	be	AUX
dpc-2653	364	4	localized	localize	VERB
dpc-2653	364	5	or	or	CCONJ
dpc-2653	364	6	the	the	DET
dpc-2653	364	7	full	full	ADJ
dpc-2653	364	8	length	length	NOUN
dpc-2653	364	9	of	of	ADP
dpc-2653	364	10	the	the	DET
dpc-2653	364	11	free	free	ADJ
dpc-2653	364	12	edge	edge	NOUN
dpc-2653	364	13	may	may	AUX
dpc-2653	364	14	be	be	AUX
dpc-2653	364	15	involved	involve	VERB
dpc-2653	364	16	.	.	PUNCT
dpc-2653	365	1	electron	electron	NOUN
dpc-2653	365	2	microscopy	microscopy	NOUN
dpc-2653	365	3	reveals	reveal	VERB
dpc-2653	365	4	horizontal	horizontal	ADJ
dpc-2653	365	5	separation	separation	NOUN
dpc-2653	365	6	of	of	ADP
dpc-2653	365	7	the	the	DET
dpc-2653	365	8	nail	nail	NOUN
dpc-2653	365	9	plate	plate	NOUN
dpc-2653	365	10	,	,	PUNCT
dpc-2653	365	11	which	which	PRON
dpc-2653	365	12	may	may	AUX
dpc-2653	365	13	,	,	PUNCT
dpc-2653	365	14	sometimes	sometimes	ADV
dpc-2653	365	15	,	,	PUNCT
dpc-2653	365	16	extend	extend	VERB
dpc-2653	365	17	up	up	ADP
dpc-2653	365	18	to	to	ADP
dpc-2653	365	19	the	the	DET
dpc-2653	365	20	proximal	proximal	ADJ
dpc-2653	365	21	nail	nail	NOUN
dpc-2653	365	22	fold	fold	NOUN
dpc-2653	365	23	.	.	PUNCT
dpc-2653	366	1	it	it	PRON
dpc-2653	366	2	also	also	ADV
dpc-2653	366	3	demonstrates	demonstrate	VERB
dpc-2653	366	4	individual	individual	ADJ
dpc-2653	366	5	cells	cell	NOUN
dpc-2653	366	6	lying	lie	VERB
dpc-2653	366	7	in	in	ADP
dpc-2653	366	8	the	the	DET
dpc-2653	366	9	empty	empty	ADJ
dpc-2653	366	10	spaces	space	NOUN
dpc-2653	366	11	.	.	PUNCT
dpc-2653	367	1	these	these	DET
dpc-2653	367	2	observations	observation	NOUN
dpc-2653	367	3	indicate	indicate	VERB
dpc-2653	367	4	lamellar	lamellar	ADJ
dpc-2653	367	5	splitting	splitting	NOUN
dpc-2653	367	6	in	in	ADP
dpc-2653	367	7	onychoschizia	onychoschizia	PROPN
dpc-2653	367	8	occurs	occur	VERB
dpc-2653	367	9	between	between	ADP
dpc-2653	367	10	the	the	DET
dpc-2653	367	11	cell	cell	NOUN
dpc-2653	367	12	layers	layer	NOUN
dpc-2653	367	13	.	.	PUNCT
dpc-2653	368	1	management	management	NOUN
dpc-2653	368	2	and	and	CCONJ
dpc-2653	368	3	prevention	prevention	NOUN
dpc-2653	368	4	counselling	counselling	NOUN
dpc-2653	368	5	for	for	ADP
dpc-2653	368	6	the	the	DET
dpc-2653	368	7	prevention	prevention	NOUN
dpc-2653	368	8	of	of	ADP
dpc-2653	368	9	nail	nail	NOUN
dpc-2653	368	10	toxic	toxic	ADJ
dpc-2653	368	11	effects	effect	NOUN
dpc-2653	368	12	is	be	AUX
dpc-2653	368	13	mandatory	mandatory	ADJ
dpc-2653	368	14	.	.	PUNCT
dpc-2653	369	1	healthcare	healthcare	NOUN
dpc-2653	369	2	professionals	professional	NOUN
dpc-2653	369	3	should	should	AUX
dpc-2653	369	4	provide	provide	VERB
dpc-2653	369	5	patients	patient	NOUN
dpc-2653	369	6	with	with	ADP
dpc-2653	369	7	clear	clear	ADJ
dpc-2653	369	8	and	and	CCONJ
dpc-2653	369	9	detailed	detailed	ADJ
dpc-2653	369	10	information	information	NOUN
dpc-2653	369	11	.	.	PUNCT
dpc-2653	370	1	the	the	DET
dpc-2653	370	2	patients	patient	NOUN
dpc-2653	370	3	should	should	AUX
dpc-2653	370	4	avoid	avoid	VERB
dpc-2653	370	5	repeated	repeat	VERB
dpc-2653	370	6	trauma	trauma	NOUN
dpc-2653	370	7	or	or	CCONJ
dpc-2653	370	8	pressure	pressure	NOUN
dpc-2653	370	9	on	on	ADP
dpc-2653	370	10	nails	nail	NOUN
dpc-2653	370	11	and	and	CCONJ
dpc-2653	370	12	nail	nail	NOUN
dpc-2653	370	13	beds	bed	NOUN
dpc-2653	370	14	or	or	CCONJ
dpc-2653	370	15	irritant	irritant	VERB
dpc-2653	370	16	regimen	regiman	NOUN
dpc-2653	370	17	,	,	PUNCT
dpc-2653	370	18	including	include	VERB
dpc-2653	370	19	manipulation	manipulation	NOUN
dpc-2653	370	20	of	of	ADP
dpc-2653	370	21	the	the	DET
dpc-2653	370	22	cuticles	cuticle	NOUN
dpc-2653	370	23	and	and	CCONJ
dpc-2653	370	24	nail	nail	NOUN
dpc-2653	370	25	biting	biting	NOUN
dpc-2653	370	26	,	,	PUNCT
dpc-2653	370	27	use	use	NOUN
dpc-2653	370	28	of	of	ADP
dpc-2653	370	29	fingernails	fingernail	NOUN
dpc-2653	370	30	as	as	ADP
dpc-2653	370	31	“	"	PUNCT
dpc-2653	370	32	tools	tool	NOUN
dpc-2653	370	33	,	,	PUNCT
dpc-2653	370	34	”	"	PUNCT
dpc-2653	370	35	prolonged	prolonged	ADJ
dpc-2653	370	36	soaking	soaking	NOUN
dpc-2653	370	37	in	in	ADP
dpc-2653	370	38	water	water	NOUN
dpc-2653	370	39	,	,	PUNCT
dpc-2653	370	40	exposure	exposure	NOUN
dpc-2653	370	41	to	to	ADP
dpc-2653	370	42	solvents	solvent	NOUN
dpc-2653	370	43	or	or	CCONJ
dpc-2653	370	44	hard	hard	ADJ
dpc-2653	370	45	chemicals	chemical	NOUN
dpc-2653	370	46	,	,	PUNCT
dpc-2653	370	47	and	and	CCONJ
dpc-2653	370	48	application	application	NOUN
dpc-2653	370	49	of	of	ADP
dpc-2653	370	50	artificial	artificial	ADJ
dpc-2653	370	51	nails	nail	NOUN
dpc-2653	370	52	.	.	PUNCT
dpc-2653	371	1	they	they	PRON
dpc-2653	371	2	are	be	AUX
dpc-2653	371	3	encouraged	encourage	VERB
dpc-2653	371	4	to	to	PART
dpc-2653	371	5	trim	trim	VERB
dpc-2653	371	6	their	their	PRON
dpc-2653	371	7	nails	nail	NOUN
dpc-2653	371	8	regularly	regularly	ADV
dpc-2653	371	9	and	and	CCONJ
dpc-2653	371	10	smooth	smooth	VERB
dpc-2653	371	11	the	the	DET
dpc-2653	371	12	edges	edge	NOUN
dpc-2653	371	13	.	.	PUNCT
dpc-2653	372	1	the	the	DET
dpc-2653	372	2	nails	nail	NOUN
dpc-2653	372	3	should	should	AUX
dpc-2653	372	4	be	be	AUX
dpc-2653	372	5	straight	straight	ADV
dpc-2653	372	6	/	/	SYM
dpc-2653	372	7	squared	squared	ADJ
dpc-2653	372	8	and	and	CCONJ
dpc-2653	372	9	not	not	PART
dpc-2653	372	10	too	too	ADV
dpc-2653	372	11	short	short	ADJ
dpc-2653	372	12	.	.	PUNCT
dpc-2653	373	1	prophylactic	prophylactic	ADJ
dpc-2653	373	2	measures	measure	NOUN
dpc-2653	373	3	include	include	VERB
dpc-2653	373	4	the	the	DET
dpc-2653	373	5	use	use	NOUN
dpc-2653	373	6	of	of	ADP
dpc-2653	373	7	cotton	cotton	NOUN
dpc-2653	373	8	gloves	glove	NOUN
dpc-2653	373	9	,	,	PUNCT
dpc-2653	373	10	comfortable	comfortable	ADJ
dpc-2653	373	11	wide	wide	ADV
dpc-2653	373	12	-	-	PUNCT
dpc-2653	373	13	fitting	fit	VERB
dpc-2653	373	14	footwear	footwear	NOUN
dpc-2653	373	15	and	and	CCONJ
dpc-2653	373	16	cotton	cotton	NOUN
dpc-2653	373	17	socks	sock	NOUN
dpc-2653	373	18	.	.	PUNCT
dpc-2653	374	1	housework	housework	NOUN
dpc-2653	374	2	should	should	AUX
dpc-2653	374	3	be	be	AUX
dpc-2653	374	4	performed	perform	VERB
dpc-2653	374	5	only	only	ADV
dpc-2653	374	6	with	with	ADP
dpc-2653	374	7	glove	glove	NOUN
dpc-2653	374	8	protection	protection	NOUN
dpc-2653	374	9	.	.	PUNCT
dpc-2653	375	1	when	when	SCONJ
dpc-2653	375	2	uv	uv	NOUN
dpc-2653	375	3	-	-	PUNCT
dpc-2653	375	4	associated	associate	VERB
dpc-2653	375	5	toxicity	toxicity	NOUN
dpc-2653	375	6	is	be	AUX
dpc-2653	375	7	related	relate	VERB
dpc-2653	375	8	to	to	ADP
dpc-2653	375	9	the	the	DET
dpc-2653	375	10	drug	drug	NOUN
dpc-2653	375	11	regimen	regimen	NOUN
dpc-2653	375	12	patients	patient	NOUN
dpc-2653	375	13	should	should	AUX
dpc-2653	375	14	be	be	AUX
dpc-2653	375	15	informed	inform	VERB
dpc-2653	375	16	and	and	CCONJ
dpc-2653	375	17	wear	wear	VERB
dpc-2653	375	18	gloves	glove	NOUN
dpc-2653	375	19	when	when	SCONJ
dpc-2653	375	20	outside	outside	ADV
dpc-2653	375	21	.	.	PUNCT
dpc-2653	376	1	nail	nail	NOUN
dpc-2653	376	2	lacquers	lacquer	NOUN
dpc-2653	376	3	are	be	AUX
dpc-2653	376	4	recommended	recommend	VERB
dpc-2653	376	5	to	to	PART
dpc-2653	376	6	limit	limit	VERB
dpc-2653	376	7	water	water	NOUN
dpc-2653	376	8	loss	loss	NOUN
dpc-2653	376	9	from	from	ADP
dpc-2653	376	10	the	the	DET
dpc-2653	376	11	nail	nail	NOUN
dpc-2653	376	12	plate	plate	NOUN
dpc-2653	376	13	(	(	PUNCT
dpc-2653	376	14	especially	especially	ADV
dpc-2653	376	15	for	for	ADP
dpc-2653	376	16	brittle	brittle	ADJ
dpc-2653	376	17	nails	nail	NOUN
dpc-2653	376	18	)	)	PUNCT
dpc-2653	376	19	.	.	PUNCT
dpc-2653	377	1	furthermore	furthermore	ADV
dpc-2653	377	2	,	,	PUNCT
dpc-2653	377	3	daily	daily	ADJ
dpc-2653	377	4	use	use	NOUN
dpc-2653	377	5	of	of	ADP
dpc-2653	377	6	topical	topical	ADJ
dpc-2653	377	7	emollients	emollient	NOUN
dpc-2653	377	8	on	on	ADP
dpc-2653	377	9	the	the	DET
dpc-2653	377	10	total	total	ADJ
dpc-2653	377	11	nail	nail	NOUN
dpc-2653	377	12	apparatus	apparatus	NOUN
dpc-2653	377	13	(	(	PUNCT
dpc-2653	377	14	cuticles	cuticle	NOUN
dpc-2653	377	15	,	,	PUNCT
dpc-2653	377	16	plate	plate	NOUN
dpc-2653	377	17	,	,	PUNCT
dpc-2653	377	18	and	and	CCONJ
dpc-2653	377	19	periungual	periungual	ADJ
dpc-2653	377	20	folds	fold	NOUN
dpc-2653	377	21	)	)	PUNCT
dpc-2653	377	22	is	be	AUX
dpc-2653	377	23	a	a	DET
dpc-2653	377	24	prophylactic	prophylactic	ADJ
dpc-2653	377	25	management	management	NOUN
dpc-2653	377	26	for	for	ADP
dpc-2653	377	27	chemotherapy	chemotherapy	NOUN
dpc-2653	377	28	-	-	PUNCT
dpc-2653	377	29	induced	induce	VERB
dpc-2653	377	30	nail	nail	NOUN
dpc-2653	377	31	toxicity	toxicity	NOUN
dpc-2653	377	32	[	[	X
dpc-2653	377	33	48	48	NUM
dpc-2653	377	34	]	]	PUNCT
dpc-2653	377	35	.	.	PUNCT
dpc-2653	378	1	in	in	ADP
dpc-2653	378	2	addition	addition	NOUN
dpc-2653	378	3	,	,	PUNCT
dpc-2653	378	4	scotté	scotté	NOUN
dpc-2653	378	5	et	et	PROPN
dpc-2653	378	6	al	al	PROPN
dpc-2653	378	7	.	.	PUNCT
dpc-2653	379	1	[	[	X
dpc-2653	379	2	25	25	NUM
dpc-2653	379	3	]	]	PUNCT
dpc-2653	379	4	have	have	AUX
dpc-2653	379	5	demonstrated	demonstrate	VERB
dpc-2653	379	6	that	that	SCONJ
dpc-2653	379	7	the	the	DET
dpc-2653	379	8	preventive	preventive	ADJ
dpc-2653	379	9	use	use	NOUN
dpc-2653	379	10	of	of	ADP
dpc-2653	379	11	frozen	frozen	ADJ
dpc-2653	379	12	gloves	glove	NOUN
dpc-2653	379	13	/	/	SYM
dpc-2653	379	14	socks	sock	NOUN
dpc-2653	379	15	in	in	ADP
dpc-2653	379	16	patients	patient	NOUN
dpc-2653	379	17	treated	treat	VERB
dpc-2653	379	18	with	with	ADP
dpc-2653	379	19	docetaxel	docetaxel	NOUN
dpc-2653	379	20	allowed	allow	VERB
dpc-2653	379	21	a	a	DET
dpc-2653	379	22	significant	significant	ADJ
dpc-2653	379	23	reduction	reduction	NOUN
dpc-2653	379	24	in	in	ADP
dpc-2653	379	25	changes	change	NOUN
dpc-2653	379	26	from	from	ADP
dpc-2653	379	27	51	51	NUM
dpc-2653	379	28	%	%	NOUN
dpc-2653	379	29	to	to	PART
dpc-2653	379	30	11	11	NUM
dpc-2653	379	31	%	%	NOUN
dpc-2653	379	32	(	(	PUNCT
dpc-2653	379	33	p=0.0001	p=0.0001	NOUN
dpc-2653	379	34	)	)	PUNCT
dpc-2653	379	35	in	in	ADP
dpc-2653	379	36	fingernails	fingernail	NOUN
dpc-2653	379	37	,	,	PUNCT
dpc-2653	379	38	and	and	CCONJ
dpc-2653	379	39	from	from	ADP
dpc-2653	379	40	21	21	NUM
dpc-2653	379	41	%	%	NOUN
dpc-2653	379	42	to	to	PART
dpc-2653	379	43	0	0	NUM
dpc-2653	379	44	%	%	NOUN
dpc-2653	379	45	in	in	ADP
dpc-2653	379	46	toenails	toenail	NOUN
dpc-2653	379	47	,	,	PUNCT
dpc-2653	379	48	with	with	ADP
dpc-2653	379	49	a	a	DET
dpc-2653	379	50	trend	trend	NOUN
dpc-2653	379	51	towards	towards	ADP
dpc-2653	379	52	a	a	DET
dpc-2653	379	53	prolongation	prolongation	NOUN
dpc-2653	379	54	(	(	PUNCT
dpc-2653	379	55	albeit	albeit	SCONJ
dpc-2653	379	56	non	non	ADJ
dpc-2653	379	57	-	-	ADJ
dpc-2653	379	58	significant	significant	ADJ
dpc-2653	379	59	)	)	PUNCT
dpc-2653	379	60	of	of	ADP
dpc-2653	379	61	the	the	DET
dpc-2653	379	62	median	median	ADJ
dpc-2653	379	63	time	time	NOUN
dpc-2653	379	64	to	to	ADP
dpc-2653	379	65	development	development	NOUN
dpc-2653	379	66	of	of	ADP
dpc-2653	379	67	these	these	DET
dpc-2653	379	68	lesions	lesion	NOUN
dpc-2653	379	69	.	.	PUNCT
dpc-2653	380	1	importantly	importantly	ADV
dpc-2653	380	2	,	,	PUNCT
dpc-2653	380	3	the	the	DET
dpc-2653	380	4	grade	grade	NOUN
dpc-2653	380	5	2	2	NUM
dpc-2653	380	6	or	or	CCONJ
dpc-2653	380	7	greater	great	ADJ
dpc-2653	380	8	nail	nail	NOUN
dpc-2653	380	9	aes	aes	NOUN
dpc-2653	380	10	were	be	AUX
dpc-2653	380	11	reduced	reduce	VERB
dpc-2653	380	12	from	from	ADP
dpc-2653	380	13	22	22	NUM
dpc-2653	380	14	%	%	NOUN
dpc-2653	380	15	to	to	PART
dpc-2653	380	16	0	0	NUM
dpc-2653	380	17	%	%	NOUN
dpc-2653	380	18	(	(	PUNCT
dpc-2653	380	19	p=0.0001	p=0.0001	NOUN
dpc-2653	380	20	)	)	PUNCT
dpc-2653	381	1	[	[	X
dpc-2653	381	2	25	25	NUM
dpc-2653	381	3	,	,	PUNCT
dpc-2653	381	4	69	69	NUM
dpc-2653	381	5	]	]	PUNCT
dpc-2653	381	6	.	.	PUNCT
dpc-2653	382	1	therefore	therefore	ADV
dpc-2653	382	2	,	,	PUNCT
dpc-2653	382	3	the	the	DET
dpc-2653	382	4	preventive	preventive	ADJ
dpc-2653	382	5	use	use	NOUN
dpc-2653	382	6	of	of	ADP
dpc-2653	382	7	frozen	frozen	ADJ
dpc-2653	382	8	gloves	glove	NOUN
dpc-2653	382	9	/	/	SYM
dpc-2653	382	10	socks	sock	NOUN
dpc-2653	382	11	should	should	AUX
dpc-2653	382	12	be	be	AUX
dpc-2653	382	13	advised	advise	VERB
dpc-2653	382	14	in	in	ADP
dpc-2653	382	15	patients	patient	NOUN
dpc-2653	382	16	treated	treat	VERB
dpc-2653	382	17	with	with	ADP
dpc-2653	382	18	taxanes	taxane	NOUN
dpc-2653	382	19	[	[	X
dpc-2653	382	20	25	25	NUM
dpc-2653	382	21	]	]	PUNCT
dpc-2653	382	22	.	.	PUNCT
dpc-2653	383	1	alternatively	alternatively	ADV
dpc-2653	383	2	,	,	PUNCT
dpc-2653	383	3	the	the	DET
dpc-2653	383	4	use	use	NOUN
dpc-2653	383	5	of	of	ADP
dpc-2653	383	6	ice	ice	NOUN
dpc-2653	383	7	packs	pack	NOUN
dpc-2653	383	8	may	may	AUX
dpc-2653	383	9	be	be	AUX
dpc-2653	383	10	a	a	DET
dpc-2653	383	11	less	less	ADV
dpc-2653	383	12	expensive	expensive	ADJ
dpc-2653	383	13	and	and	CCONJ
dpc-2653	383	14	effective	effective	ADJ
dpc-2653	383	15	strategy	strategy	NOUN
dpc-2653	383	16	with	with	ADP
dpc-2653	383	17	similar	similar	ADJ
dpc-2653	383	18	efficacy	efficacy	NOUN
dpc-2653	383	19	[	[	X
dpc-2653	383	20	27	27	NUM
dpc-2653	383	21	]	]	PUNCT
dpc-2653	383	22	.	.	PUNCT
dpc-2653	384	1	in	in	ADP
dpc-2653	384	2	addition	addition	NOUN
dpc-2653	384	3	to	to	ADP
dpc-2653	384	4	preventing	prevent	VERB
dpc-2653	384	5	nail	nail	NOUN
dpc-2653	384	6	toxicities	toxicity	NOUN
dpc-2653	384	7	,	,	PUNCT
dpc-2653	384	8	frozen	frozen	ADJ
dpc-2653	384	9	gloves	glove	NOUN
dpc-2653	384	10	or	or	CCONJ
dpc-2653	384	11	ice	ice	NOUN
dpc-2653	384	12	packs	pack	NOUN
dpc-2653	384	13	have	have	AUX
dpc-2653	384	14	been	be	AUX
dpc-2653	384	15	shown	show	VERB
dpc-2653	384	16	to	to	PART
dpc-2653	384	17	decrease	decrease	VERB
dpc-2653	384	18	the	the	DET
dpc-2653	384	19	incidence	incidence	NOUN
dpc-2653	384	20	of	of	ADP
dpc-2653	384	21	peripheral	peripheral	ADJ
dpc-2653	384	22	neuropathy	neuropathy	ADJ
dpc-2653	384	23	,	,	PUNCT
dpc-2653	384	24	another	another	DET
dpc-2653	384	25	potentially	potentially	ADV
dpc-2653	384	26	dose	dose	NOUN
dpc-2653	384	27	-	-	PUNCT
dpc-2653	384	28	limiting	limit	VERB
dpc-2653	384	29	adverse	adverse	ADJ
dpc-2653	384	30	event	event	NOUN
dpc-2653	384	31	.	.	PUNCT
dpc-2653	385	1	it	it	PRON
dpc-2653	385	2	is	be	AUX
dpc-2653	385	3	intriguing	intriguing	ADJ
dpc-2653	385	4	that	that	SCONJ
dpc-2653	385	5	despite	despite	SCONJ
dpc-2653	385	6	the	the	DET
dpc-2653	385	7	simplicity	simplicity	NOUN
dpc-2653	385	8	and	and	CCONJ
dpc-2653	385	9	effectiveness	effectiveness	NOUN
dpc-2653	385	10	of	of	ADP
dpc-2653	385	11	this	this	DET
dpc-2653	385	12	intervention	intervention	NOUN
dpc-2653	385	13	,	,	PUNCT
dpc-2653	385	14	it	it	PRON
dpc-2653	385	15	is	be	AUX
dpc-2653	385	16	not	not	PART
dpc-2653	385	17	universally	universally	ADV
dpc-2653	385	18	employed	employ	VERB
dpc-2653	385	19	.	.	PUNCT
dpc-2653	386	1	in	in	ADP
dpc-2653	386	2	case	case	NOUN
dpc-2653	386	3	onycholysis	onycholysis	NOUN
dpc-2653	386	4	develops	develop	VERB
dpc-2653	386	5	,	,	PUNCT
dpc-2653	386	6	excising	excise	VERB
dpc-2653	386	7	the	the	DET
dpc-2653	386	8	nail	nail	NOUN
dpc-2653	386	9	plate	plate	NOUN
dpc-2653	386	10	(	(	PUNCT
dpc-2653	386	11	partially	partially	ADV
dpc-2653	386	12	or	or	CCONJ
dpc-2653	386	13	totally	totally	ADV
dpc-2653	386	14	)	)	PUNCT
dpc-2653	386	15	may	may	AUX
dpc-2653	386	16	be	be	AUX
dpc-2653	386	17	necessary	necessary	ADJ
dpc-2653	386	18	(	(	PUNCT
dpc-2653	386	19	figure	figure	NOUN
dpc-2653	386	20	4	4	NUM
dpc-2653	386	21	)	)	PUNCT
dpc-2653	386	22	,	,	PUNCT
dpc-2653	386	23	especially	especially	ADV
dpc-2653	386	24	in	in	ADP
dpc-2653	386	25	severe	severe	ADJ
dpc-2653	386	26	and	and	CCONJ
dpc-2653	386	27	painful	painful	ADJ
dpc-2653	386	28	lesions	lesion	NOUN
dpc-2653	386	29	,	,	PUNCT
dpc-2653	386	30	or	or	CCONJ
dpc-2653	386	31	when	when	SCONJ
dpc-2653	386	32	associated	associate	VERB
dpc-2653	386	33	with	with	ADP
dpc-2653	386	34	a	a	DET
dpc-2653	386	35	pressure	pressure	NOUN
dpc-2653	386	36	the	the	DET
dpc-2653	386	37	impact	impact	NOUN
dpc-2653	386	38	of	of	ADP
dpc-2653	386	39	taxane	taxane	NOUN
dpc-2653	386	40	-	-	PUNCT
dpc-2653	386	41	related	relate	VERB
dpc-2653	386	42	onycholysis	onycholysis	NOUN
dpc-2653	386	43	on	on	ADP
dpc-2653	386	44	the	the	DET
dpc-2653	386	45	quality	quality	NOUN
dpc-2653	386	46	of	of	ADP
dpc-2653	386	47	life	life	NOUN
dpc-2653	386	48	and	and	CCONJ
dpc-2653	386	49	daily	daily	ADJ
dpc-2653	386	50	activities	activity	NOUN
dpc-2653	386	51	varies	vary	VERB
dpc-2653	386	52	;	;	PUNCT
dpc-2653	386	53	effects	effect	NOUN
dpc-2653	386	54	depend	depend	VERB
dpc-2653	386	55	on	on	ADP
dpc-2653	386	56	the	the	DET
dpc-2653	386	57	number	number	NOUN
dpc-2653	386	58	of	of	ADP
dpc-2653	386	59	digits	digit	NOUN
dpc-2653	386	60	involved	involve	VERB
dpc-2653	386	61	,	,	PUNCT
dpc-2653	386	62	the	the	DET
dpc-2653	386	63	degree	degree	NOUN
dpc-2653	386	64	of	of	ADP
dpc-2653	386	65	detachment	detachment	NOUN
dpc-2653	386	66	,	,	PUNCT
dpc-2653	386	67	and	and	CCONJ
dpc-2653	386	68	the	the	DET
dpc-2653	386	69	extent	extent	NOUN
dpc-2653	386	70	of	of	ADP
dpc-2653	386	71	pain	pain	NOUN
dpc-2653	386	72	and	and	CCONJ
dpc-2653	386	73	if	if	SCONJ
dpc-2653	386	74	significant	significant	ADJ
dpc-2653	386	75	it	it	PRON
dpc-2653	386	76	can	can	AUX
dpc-2653	386	77	result	result	VERB
dpc-2653	386	78	in	in	ADP
dpc-2653	386	79	treatment	treatment	NOUN
dpc-2653	386	80	interruption	interruption	NOUN
dpc-2653	386	81	[	[	X
dpc-2653	386	82	28	28	NUM
dpc-2653	386	83	,	,	PUNCT
dpc-2653	386	84	29	29	NUM
dpc-2653	386	85	]	]	PUNCT
dpc-2653	386	86	.	.	PUNCT
dpc-2653	387	1	therefore	therefore	ADV
dpc-2653	387	2	,	,	PUNCT
dpc-2653	387	3	management	management	NOUN
dpc-2653	387	4	of	of	ADP
dpc-2653	387	5	onycholysis	onycholysis	NOUN
dpc-2653	387	6	depends	depend	VERB
dpc-2653	387	7	on	on	ADP
dpc-2653	387	8	the	the	DET
dpc-2653	387	9	clinical	clinical	ADJ
dpc-2653	387	10	grading	grading	NOUN
dpc-2653	387	11	(	(	PUNCT
dpc-2653	387	12	i.e.	i.e.	X
dpc-2653	387	13	,	,	PUNCT
dpc-2653	387	14	national	national	ADJ
dpc-2653	387	15	cancer	cancer	PROPN
dpc-2653	387	16	institute	institute	PROPN
dpc-2653	387	17	,	,	PUNCT
dpc-2653	387	18	common	common	ADJ
dpc-2653	387	19	terminology	terminology	NOUN
dpc-2653	387	20	criteria	criterion	NOUN
dpc-2653	387	21	for	for	ADP
dpc-2653	387	22	adverse	adverse	ADJ
dpc-2653	387	23	events	event	NOUN
dpc-2653	387	24	(	(	PUNCT
dpc-2653	387	25	ctcae	ctcae	NOUN
dpc-2653	387	26	)	)	PUNCT
dpc-2653	387	27	v4.02	v4.02	PROPN
dpc-2653	387	28	)	)	PUNCT
dpc-2653	387	29	and	and	CCONJ
dpc-2653	387	30	impact	impact	NOUN
dpc-2653	387	31	on	on	ADP
dpc-2653	387	32	activities	activity	NOUN
dpc-2653	387	33	of	of	ADP
dpc-2653	387	34	daily	daily	ADJ
dpc-2653	387	35	living	live	VERB
dpc-2653	388	1	[	[	X
dpc-2653	388	2	38	38	NUM
dpc-2653	388	3	]	]	PUNCT
dpc-2653	388	4	(	(	PUNCT
dpc-2653	388	5	table	table	NOUN
dpc-2653	388	6	1	1	NUM
dpc-2653	388	7	)	)	PUNCT
dpc-2653	388	8	.	.	PUNCT
dpc-2653	389	1	onycholysis	onycholysis	NOUN
dpc-2653	389	2	is	be	AUX
dpc-2653	389	3	slowly	slowly	ADV
dpc-2653	389	4	reversible	reversible	ADJ
dpc-2653	389	5	after	after	ADP
dpc-2653	389	6	treatment	treatment	NOUN
dpc-2653	389	7	,	,	PUNCT
dpc-2653	389	8	however	however	ADV
dpc-2653	389	9	chronic	chronic	ADJ
dpc-2653	389	10	onycholysis	onycholysis	NOUN
dpc-2653	389	11	can	can	AUX
dpc-2653	389	12	lead	lead	VERB
dpc-2653	389	13	to	to	ADP
dpc-2653	389	14	nail	nail	NOUN
dpc-2653	389	15	bed	bed	NOUN
dpc-2653	389	16	keratinization	keratinization	NOUN
dpc-2653	389	17	and	and	CCONJ
dpc-2653	389	18	persistent	persistent	ADJ
dpc-2653	389	19	subungual	subungual	ADJ
dpc-2653	389	20	hyperkeratosis	hyperkeratosis	NOUN
dpc-2653	389	21	[	[	X
dpc-2653	389	22	22	22	NUM
dpc-2653	389	23	,	,	PUNCT
dpc-2653	389	24	74	74	NUM
dpc-2653	389	25	]	]	PUNCT
dpc-2653	389	26	.	.	PUNCT
dpc-2653	390	1	therefore	therefore	ADV
dpc-2653	390	2	,	,	PUNCT
dpc-2653	390	3	it	it	PRON
dpc-2653	390	4	is	be	AUX
dpc-2653	390	5	crucial	crucial	ADJ
dpc-2653	390	6	to	to	PART
dpc-2653	390	7	promote	promote	VERB
dpc-2653	390	8	nail	nail	NOUN
dpc-2653	390	9	reattachment	reattachment	NOUN
dpc-2653	390	10	as	as	ADV
dpc-2653	390	11	early	early	ADV
dpc-2653	390	12	as	as	ADP
dpc-2653	390	13	possible	possible	ADJ
dpc-2653	390	14	by	by	ADP
dpc-2653	390	15	preventing	prevent	VERB
dpc-2653	390	16	further	further	ADJ
dpc-2653	390	17	toxicity	toxicity	NOUN
dpc-2653	390	18	and	and	CCONJ
dpc-2653	390	19	treating	treat	VERB
dpc-2653	390	20	underlying	underlying	ADJ
dpc-2653	390	21	infections	infection	NOUN
dpc-2653	390	22	,	,	PUNCT
dpc-2653	390	23	otherwise	otherwise	ADV
dpc-2653	390	24	onycholysis	onycholysis	NOUN
dpc-2653	390	25	may	may	AUX
dpc-2653	390	26	become	become	VERB
dpc-2653	390	27	permanent	permanent	ADJ
dpc-2653	390	28	.	.	PUNCT
dpc-2653	391	1	paronychia	paronychia	PROPN
dpc-2653	391	2	paronychia	paronychia	PROPN
dpc-2653	391	3	is	be	AUX
dpc-2653	391	4	the	the	DET
dpc-2653	391	5	result	result	NOUN
dpc-2653	391	6	of	of	ADP
dpc-2653	391	7	inflammation	inflammation	NOUN
dpc-2653	391	8	of	of	ADP
dpc-2653	391	9	proximal	proximal	ADJ
dpc-2653	391	10	/	/	SYM
dpc-2653	391	11	lateral	lateral	ADJ
dpc-2653	391	12	nail	nail	NOUN
dpc-2653	391	13	folds	fold	NOUN
dpc-2653	391	14	with	with	ADP
dpc-2653	391	15	erythema	erythema	ADJ
dpc-2653	391	16	,	,	PUNCT
dpc-2653	391	17	edema	edema	NOUN
dpc-2653	391	18	,	,	PUNCT
dpc-2653	391	19	tenderness	tenderness	NOUN
dpc-2653	391	20	or	or	CCONJ
dpc-2653	391	21	pain	pain	NOUN
dpc-2653	391	22	of	of	ADP
dpc-2653	391	23	the	the	DET
dpc-2653	391	24	nail	nail	NOUN
dpc-2653	391	25	folds	fold	NOUN
dpc-2653	391	26	and	and	CCONJ
dpc-2653	391	27	impaired	impaired	ADJ
dpc-2653	391	28	activity	activity	NOUN
dpc-2653	391	29	.	.	PUNCT
dpc-2653	392	1	it	it	PRON
dpc-2653	392	2	usually	usually	ADV
dpc-2653	392	3	develops	develop	VERB
dpc-2653	392	4	soon	soon	ADV
dpc-2653	392	5	after	after	ADP
dpc-2653	392	6	intake	intake	NOUN
dpc-2653	392	7	of	of	ADP
dpc-2653	392	8	the	the	DET
dpc-2653	392	9	drug	drug	NOUN
dpc-2653	392	10	,	,	PUNCT
dpc-2653	392	11	involves	involve	VERB
dpc-2653	392	12	one	one	NUM
dpc-2653	392	13	or	or	CCONJ
dpc-2653	392	14	several	several	ADJ
dpc-2653	392	15	nails	nail	NOUN
dpc-2653	392	16	and	and	CCONJ
dpc-2653	392	17	is	be	AUX
dpc-2653	392	18	thought	think	VERB
dpc-2653	392	19	to	to	PART
dpc-2653	392	20	be	be	AUX
dpc-2653	392	21	the	the	DET
dpc-2653	392	22	result	result	NOUN
dpc-2653	392	23	of	of	ADP
dpc-2653	392	24	the	the	DET
dpc-2653	392	25	toxic	toxic	ADJ
dpc-2653	392	26	effect	effect	NOUN
dpc-2653	392	27	of	of	ADP
dpc-2653	392	28	the	the	DET
dpc-2653	392	29	drug	drug	NOUN
dpc-2653	392	30	on	on	ADP
dpc-2653	392	31	nail	nail	NOUN
dpc-2653	392	32	epithelium	epithelium	NOUN
dpc-2653	393	1	[	[	X
dpc-2653	393	2	2	2	NUM
dpc-2653	393	3	,	,	PUNCT
dpc-2653	393	4	8	8	NUM
dpc-2653	393	5	]	]	PUNCT
dpc-2653	393	6	.	.	PUNCT
dpc-2653	394	1	paronychia	paronychia	PROPN
dpc-2653	394	2	is	be	AUX
dpc-2653	394	3	a	a	DET
dpc-2653	394	4	frequent	frequent	ADJ
dpc-2653	394	5	but	but	CCONJ
dpc-2653	394	6	uncommonly	uncommonly	ADV
dpc-2653	394	7	reported	report	VERB
dpc-2653	394	8	adverse	adverse	ADJ
dpc-2653	394	9	effect	effect	NOUN
dpc-2653	394	10	of	of	ADP
dpc-2653	394	11	epidermal	epidermal	ADJ
dpc-2653	394	12	growth	growth	NOUN
dpc-2653	394	13	factor	factor	NOUN
dpc-2653	394	14	inhibitors	inhibitor	NOUN
dpc-2653	394	15	which	which	PRON
dpc-2653	394	16	is	be	AUX
dpc-2653	394	17	the	the	DET
dpc-2653	394	18	result	result	NOUN
dpc-2653	394	19	of	of	ADP
dpc-2653	394	20	aberrant	aberrant	ADJ
dpc-2653	394	21	vascular	vascular	ADJ
dpc-2653	394	22	response	response	NOUN
dpc-2653	394	23	affecting	affect	VERB
dpc-2653	394	24	nail	nail	NOUN
dpc-2653	394	25	folds	fold	NOUN
dpc-2653	395	1	[	[	X
dpc-2653	395	2	75	75	NUM
dpc-2653	395	3	,	,	PUNCT
dpc-2653	395	4	76	76	NUM
dpc-2653	395	5	]	]	PUNCT
dpc-2653	395	6	.	.	PUNCT
dpc-2653	396	1	except	except	SCONJ
dpc-2653	396	2	for	for	ADP
dpc-2653	396	3	anti	anti	ADJ
dpc-2653	396	4	-	-	ADJ
dpc-2653	396	5	egfr	egfr	ADJ
dpc-2653	396	6	targeted	target	VERB
dpc-2653	396	7	therapy	therapy	NOUN
dpc-2653	396	8	,	,	PUNCT
dpc-2653	396	9	ret	ret	NOUN
dpc-2653	396	10	inhibitor	inhibitor	NOUN
dpc-2653	396	11	,	,	PUNCT
dpc-2653	396	12	mtor	mtor	NOUN
dpc-2653	396	13	inhibitors	inhibitor	NOUN
dpc-2653	396	14	,	,	PUNCT
dpc-2653	396	15	anti	anti	ADJ
dpc-2653	396	16	-	-	ADJ
dpc-2653	396	17	mek	mek	NOUN
dpc-2653	396	18	,	,	PUNCT
dpc-2653	396	19	anti	anti	ADJ
dpc-2653	396	20	-	-	ADJ
dpc-2653	396	21	her	her	PRON
dpc-2653	396	22	,	,	PUNCT
dpc-2653	396	23	5	5	NUM
dpc-2653	396	24	-	-	PUNCT
dpc-2653	396	25	fluorouracil	fluorouracil	NOUN
dpc-2653	396	26	and	and	CCONJ
dpc-2653	396	27	docetaxel	docetaxel	NOUN
dpc-2653	396	28	have	have	AUX
dpc-2653	396	29	been	be	AUX
dpc-2653	396	30	reported	report	VERB
dpc-2653	396	31	to	to	PART
dpc-2653	396	32	develop	develop	VERB
dpc-2653	396	33	paronychia	paronychia	NOUN
dpc-2653	396	34	as	as	ADV
dpc-2653	396	35	well	well	ADV
dpc-2653	396	36	[	[	X
dpc-2653	396	37	4	4	X
dpc-2653	396	38	]	]	X
dpc-2653	396	39	(	(	PUNCT
dpc-2653	396	40	table	table	NOUN
dpc-2653	396	41	5	5	NUM
dpc-2653	396	42	)	)	PUNCT
dpc-2653	396	43	.	.	PUNCT
dpc-2653	397	1	brittle	brittle	ADJ
dpc-2653	397	2	nails	nail	NOUN
dpc-2653	397	3	and	and	CCONJ
dpc-2653	397	4	decreased	decrease	VERB
dpc-2653	397	5	nail	nail	NOUN
dpc-2653	397	6	growth	growth	NOUN
dpc-2653	397	7	a	a	DET
dpc-2653	397	8	decrease	decrease	NOUN
dpc-2653	397	9	in	in	ADP
dpc-2653	397	10	nail	nail	NOUN
dpc-2653	397	11	plate	plate	NOUN
dpc-2653	397	12	growth	growth	NOUN
dpc-2653	397	13	is	be	AUX
dpc-2653	397	14	commonly	commonly	ADV
dpc-2653	397	15	noted	note	VERB
dpc-2653	397	16	with	with	ADP
dpc-2653	397	17	chemotherapy	chemotherapy	NOUN
dpc-2653	397	18	,	,	PUNCT
dpc-2653	397	19	although	although	SCONJ
dpc-2653	397	20	it	it	PRON
dpc-2653	397	21	will	will	AUX
dpc-2653	397	22	usually	usually	ADV
dpc-2653	397	23	go	go	VERB
dpc-2653	397	24	unnoticed	unnoticed	ADJ
dpc-2653	397	25	by	by	ADP
dpc-2653	397	26	patients	patient	NOUN
dpc-2653	397	27	or	or	CCONJ
dpc-2653	397	28	physicians	physician	NOUN
dpc-2653	397	29	.	.	PUNCT
dpc-2653	398	1	the	the	DET
dpc-2653	398	2	nails	nail	NOUN
dpc-2653	398	3	are	be	AUX
dpc-2653	398	4	often	often	ADV
dpc-2653	398	5	fragile	fragile	ADJ
dpc-2653	398	6	and	and	CCONJ
dpc-2653	398	7	thinner	thin	ADJ
dpc-2653	398	8	,	,	PUNCT
dpc-2653	398	9	which	which	PRON
dpc-2653	398	10	can	can	AUX
dpc-2653	398	11	lead	lead	VERB
dpc-2653	398	12	to	to	ADP
dpc-2653	398	13	koilonychia	koilonychia	NOUN
dpc-2653	398	14	,	,	PUNCT
dpc-2653	398	15	onychorrhexis	onychorrhexis	ADJ
dpc-2653	398	16	,	,	PUNCT
dpc-2653	398	17	or	or	CCONJ
dpc-2653	398	18	onychoschizia	onychoschizia	PROPN
dpc-2653	398	19	after	after	ADP
dpc-2653	398	20	several	several	ADJ
dpc-2653	398	21	cycles	cycle	NOUN
dpc-2653	398	22	of	of	ADP
dpc-2653	398	23	chemotherapy	chemotherapy	NOUN
dpc-2653	398	24	[	[	X
dpc-2653	398	25	74	74	NUM
dpc-2653	398	26	]	]	PUNCT
dpc-2653	398	27	.	.	PUNCT
dpc-2653	399	1	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	399	2	agents	agent	NOUN
dpc-2653	399	3	such	such	ADJ
dpc-2653	399	4	as	as	ADP
dpc-2653	399	5	cetuximab	cetuximab	NOUN
dpc-2653	399	6	,	,	PUNCT
dpc-2653	399	7	panitumumab	panitumumab	NOUN
dpc-2653	399	8	,	,	PUNCT
dpc-2653	399	9	erlotinib	erlotinib	NOUN
dpc-2653	399	10	,	,	PUNCT
dpc-2653	399	11	gefitinib	gefitinib	NOUN
dpc-2653	399	12	,	,	PUNCT
dpc-2653	399	13	necitumumab	necitumumab	NOUN
dpc-2653	399	14	,	,	PUNCT
dpc-2653	399	15	lapatinib	lapatinib	PROPN
dpc-2653	399	16	,	,	PUNCT
dpc-2653	399	17	afatinib	afatinib	NOUN
dpc-2653	399	18	,	,	PUNCT
dpc-2653	399	19	dacomitinib	dacomitinib	NOUN
dpc-2653	399	20	,	,	PUNCT
dpc-2653	399	21	trametinib	trametinib	NOUN
dpc-2653	399	22	,	,	PUNCT
dpc-2653	399	23	cobimetinib	cobimetinib	NOUN
dpc-2653	399	24	,	,	PUNCT
dpc-2653	399	25	selumetinib	selumetinib	NOUN
dpc-2653	399	26	,	,	PUNCT
dpc-2653	399	27	everolimus	everolimus	ADJ
dpc-2653	399	28	,	,	PUNCT
dpc-2653	399	29	temsirolimus	temsirolimus	NOUN
dpc-2653	399	30	,	,	PUNCT
dpc-2653	399	31	ibrutinib	ibrutinib	PROPN
dpc-2653	399	32	,	,	PUNCT
dpc-2653	399	33	sunitinib	sunitinib	NOUN
dpc-2653	399	34	,	,	PUNCT
dpc-2653	399	35	sorafenib	sorafenib	NOUN
dpc-2653	399	36	,	,	PUNCT
dpc-2653	399	37	cabozantinib	cabozantinib	ADV
dpc-2653	399	38	,	,	PUNCT
dpc-2653	399	39	axitinib	axitinib	NOUN
dpc-2653	399	40	,	,	PUNCT
dpc-2653	399	41	pazotinib	pazotinib	NOUN
dpc-2653	399	42	,	,	PUNCT
dpc-2653	399	43	regorafenib	regorafenib	NOUN
dpc-2653	399	44	,	,	PUNCT
dpc-2653	399	45	docetaxel	docetaxel	NOUN
dpc-2653	399	46	and	and	CCONJ
dpc-2653	399	47	paclitaxelare	paclitaxelare	NOUN
dpc-2653	399	48	associated	associate	VERB
dpc-2653	399	49	with	with	ADP
dpc-2653	399	50	brittle	brittle	ADJ
dpc-2653	399	51	nails	nail	NOUN
dpc-2653	399	52	(	(	PUNCT
dpc-2653	399	53	table	table	NOUN
dpc-2653	399	54	5	5	NUM
dpc-2653	399	55	)	)	PUNCT
dpc-2653	399	56	.	.	PUNCT
dpc-2653	400	1	koilonychia	koilonychia	PROPN
dpc-2653	400	2	is	be	AUX
dpc-2653	400	3	a	a	DET
dpc-2653	400	4	common	common	ADJ
dpc-2653	400	5	nail	nail	NOUN
dpc-2653	400	6	dystrophy	dystrophy	NOUN
dpc-2653	400	7	in	in	ADP
dpc-2653	400	8	which	which	PRON
dpc-2653	400	9	the	the	DET
dpc-2653	400	10	dorsal	dorsal	NOUN
dpc-2653	400	11	surface	surface	NOUN
dpc-2653	400	12	of	of	ADP
dpc-2653	400	13	the	the	DET
dpc-2653	400	14	nail	nail	NOUN
dpc-2653	400	15	plate	plate	NOUN
dpc-2653	400	16	becomes	become	VERB
dpc-2653	400	17	flat	flat	ADJ
dpc-2653	400	18	or	or	CCONJ
dpc-2653	400	19	truly	truly	ADV
dpc-2653	400	20	concave	concave	VERB
dpc-2653	400	21	.	.	PUNCT
dpc-2653	401	1	it	it	PRON
dpc-2653	401	2	is	be	AUX
dpc-2653	401	3	derived	derive	VERB
dpc-2653	401	4	from	from	ADP
dpc-2653	401	5	the	the	DET
dpc-2653	401	6	greek	greek	ADJ
dpc-2653	401	7	word	word	NOUN
dpc-2653	401	8	koilos	koilos	PROPN
dpc-2653	401	9	,	,	PUNCT
dpc-2653	401	10	meaning	mean	VERB
dpc-2653	401	11	hollow	hollow	NOUN
dpc-2653	401	12	.	.	PUNCT
dpc-2653	402	1	pathogenesis	pathogenesis	NOUN
dpc-2653	402	2	of	of	ADP
dpc-2653	402	3	koilonychia	koilonychia	NOUN
dpc-2653	402	4	is	be	AUX
dpc-2653	402	5	not	not	PART
dpc-2653	402	6	known	know	VERB
dpc-2653	402	7	but	but	CCONJ
dpc-2653	402	8	it	it	PRON
dpc-2653	402	9	is	be	AUX
dpc-2653	402	10	suggested	suggest	VERB
dpc-2653	402	11	that	that	SCONJ
dpc-2653	402	12	anoxia	anoxia	NOUN
dpc-2653	402	13	and	and	CCONJ
dpc-2653	402	14	atrophy	atrophy	NOUN
dpc-2653	402	15	of	of	ADP
dpc-2653	402	16	the	the	DET
dpc-2653	402	17	distal	distal	ADJ
dpc-2653	402	18	matrix	matrix	NOUN
dpc-2653	402	19	are	be	AUX
dpc-2653	402	20	contributory	contributory	PROPN
dpc-2653	402	21	.	.	PUNCT
dpc-2653	403	1	koilonychia	koilonychia	PROPN
dpc-2653	403	2	is	be	AUX
dpc-2653	403	3	the	the	DET
dpc-2653	403	4	converse	converse	NOUN
dpc-2653	403	5	of	of	ADP
dpc-2653	403	6	clubbing	clubbing	NOUN
dpc-2653	403	7	and	and	CCONJ
dpc-2653	403	8	it	it	PRON
dpc-2653	403	9	is	be	AUX
dpc-2653	403	10	more	more	ADV
dpc-2653	403	11	appreciated	appreciated	ADJ
dpc-2653	403	12	when	when	SCONJ
dpc-2653	403	13	viewed	view	VERB
dpc-2653	403	14	from	from	ADP
dpc-2653	403	15	the	the	DET
dpc-2653	403	16	side	side	NOUN
dpc-2653	403	17	.	.	PUNCT
dpc-2653	404	1	when	when	SCONJ
dpc-2653	404	2	a	a	DET
dpc-2653	404	3	drop	drop	NOUN
dpc-2653	404	4	of	of	ADP
dpc-2653	404	5	water	water	NOUN
dpc-2653	404	6	is	be	AUX
dpc-2653	404	7	put	put	VERB
dpc-2653	404	8	on	on	ADP
dpc-2653	404	9	the	the	DET
dpc-2653	404	10	surface	surface	NOUN
dpc-2653	404	11	,	,	PUNCT
dpc-2653	404	12	it	it	PRON
dpc-2653	404	13	will	will	AUX
dpc-2653	404	14	not	not	PART
dpc-2653	404	15	fall	fall	VERB
dpc-2653	404	16	off	off	ADP
dpc-2653	404	17	.	.	PUNCT
dpc-2653	405	1	it	it	PRON
dpc-2653	405	2	should	should	AUX
dpc-2653	405	3	be	be	AUX
dpc-2653	405	4	noted	note	VERB
dpc-2653	405	5	that	that	SCONJ
dpc-2653	405	6	nails	nail	NOUN
dpc-2653	405	7	in	in	ADP
dpc-2653	405	8	koilonychia	koilonychia	NOUN
dpc-2653	405	9	are	be	AUX
dpc-2653	405	10	brittle	brittle	ADJ
dpc-2653	405	11	.	.	PUNCT
dpc-2653	406	1	it	it	PRON
dpc-2653	406	2	is	be	AUX
dpc-2653	406	3	commonly	commonly	ADV
dpc-2653	406	4	seen	see	VERB
dpc-2653	406	5	in	in	ADP
dpc-2653	406	6	fingernails	fingernail	NOUN
dpc-2653	406	7	rather	rather	ADV
dpc-2653	406	8	than	than	ADP
dpc-2653	406	9	toenails	toenail	NOUN
dpc-2653	406	10	.	.	PUNCT
dpc-2653	407	1	docetaxel	docetaxel	PROPN
dpc-2653	407	2	and	and	CCONJ
dpc-2653	407	3	paclitaxel	paclitaxel	PROPN
dpc-2653	407	4	may	may	AUX
dpc-2653	407	5	cause	cause	VERB
dpc-2653	407	6	koilonychia	koilonychia	NOUN
dpc-2653	407	7	more	more	ADV
dpc-2653	407	8	often	often	ADV
dpc-2653	407	9	(	(	PUNCT
dpc-2653	407	10	table	table	NOUN
dpc-2653	407	11	5	5	NUM
dpc-2653	407	12	)	)	PUNCT
dpc-2653	407	13	.	.	PUNCT
dpc-2653	408	1	review	review	VERB
dpc-2653	408	2	|	|	ADV
dpc-2653	408	3	dermatol	dermatol	ADJ
dpc-2653	408	4	pract	pract	NOUN
dpc-2653	408	5	concept	concept	NOUN
dpc-2653	408	6	.	.	PUNCT
dpc-2653	409	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	409	2	15	15	NUM
dpc-2653	409	3	cryotherapy	cryotherapy	NOUN
dpc-2653	409	4	’s	’s	PART
dpc-2653	409	5	effect	effect	NOUN
dpc-2653	409	6	is	be	AUX
dpc-2653	409	7	related	relate	VERB
dpc-2653	409	8	to	to	ADP
dpc-2653	409	9	cold	cold	ADJ
dpc-2653	409	10	-	-	PUNCT
dpc-2653	409	11	induced	induce	VERB
dpc-2653	409	12	vasoconstriction	vasoconstriction	NOUN
dpc-2653	409	13	,	,	PUNCT
dpc-2653	409	14	which	which	PRON
dpc-2653	409	15	reduces	reduce	VERB
dpc-2653	409	16	the	the	DET
dpc-2653	409	17	quantity	quantity	NOUN
dpc-2653	409	18	of	of	ADP
dpc-2653	409	19	drugs	drug	NOUN
dpc-2653	409	20	reaching	reach	VERB
dpc-2653	409	21	the	the	DET
dpc-2653	409	22	proliferating	proliferate	VERB
dpc-2653	409	23	stem	stem	NOUN
dpc-2653	409	24	cells	cell	NOUN
dpc-2653	409	25	.	.	PUNCT
dpc-2653	410	1	for	for	ADP
dpc-2653	410	2	patients	patient	NOUN
dpc-2653	410	3	who	who	PRON
dpc-2653	410	4	can	can	AUX
dpc-2653	410	5	afford	afford	VERB
dpc-2653	410	6	them	they	PRON
dpc-2653	410	7	,	,	PUNCT
dpc-2653	410	8	tolerate	tolerate	VERB
dpc-2653	410	9	discomfort	discomfort	NOUN
dpc-2653	410	10	and	and	CCONJ
dpc-2653	410	11	exhibit	exhibit	NOUN
dpc-2653	410	12	compliance	compliance	NOUN
dpc-2653	410	13	,	,	PUNCT
dpc-2653	410	14	these	these	DET
dpc-2653	410	15	prophylactic	prophylactic	ADJ
dpc-2653	410	16	managements	management	NOUN
dpc-2653	410	17	of	of	ADP
dpc-2653	410	18	taxane	taxane	NOUN
dpc-2653	410	19	-	-	PUNCT
dpc-2653	410	20	induced	induce	VERB
dpc-2653	410	21	nail	nail	NOUN
dpc-2653	410	22	toxicity	toxicity	NOUN
dpc-2653	410	23	can	can	AUX
dpc-2653	410	24	be	be	AUX
dpc-2653	410	25	suggested	suggest	VERB
dpc-2653	410	26	as	as	ADP
dpc-2653	410	27	an	an	DET
dpc-2653	410	28	option	option	NOUN
dpc-2653	410	29	to	to	PART
dpc-2653	410	30	improve	improve	VERB
dpc-2653	410	31	patients	patient	NOUN
dpc-2653	410	32	’	'	PUNCT
dpc-2653	410	33	quality	quality	NOUN
dpc-2653	410	34	of	of	ADP
dpc-2653	410	35	life	life	NOUN
dpc-2653	410	36	and	and	CCONJ
dpc-2653	410	37	functional	functional	ADJ
dpc-2653	410	38	statuses	status	NOUN
dpc-2653	410	39	.	.	PUNCT
dpc-2653	411	1	however	however	ADV
dpc-2653	411	2	,	,	PUNCT
dpc-2653	411	3	future	future	ADJ
dpc-2653	411	4	investigations	investigation	NOUN
dpc-2653	411	5	and	and	CCONJ
dpc-2653	411	6	studies	study	NOUN
dpc-2653	411	7	are	be	AUX
dpc-2653	411	8	needed	need	VERB
dpc-2653	411	9	to	to	PART
dpc-2653	411	10	establish	establish	VERB
dpc-2653	411	11	the	the	DET
dpc-2653	411	12	routine	routine	ADJ
dpc-2653	411	13	usage	usage	NOUN
dpc-2653	411	14	protocols	protocol	NOUN
dpc-2653	411	15	,	,	PUNCT
dpc-2653	411	16	standard	standard	ADJ
dpc-2653	411	17	outcome	outcome	NOUN
dpc-2653	411	18	measures	measure	NOUN
dpc-2653	411	19	,	,	PUNCT
dpc-2653	411	20	long	long	ADJ
dpc-2653	411	21	-	-	PUNCT
dpc-2653	411	22	term	term	NOUN
dpc-2653	411	23	efficacy	efficacy	NOUN
dpc-2653	411	24	and	and	CCONJ
dpc-2653	411	25	safety	safety	NOUN
dpc-2653	411	26	for	for	ADP
dpc-2653	411	27	these	these	DET
dpc-2653	411	28	interventions	intervention	NOUN
dpc-2653	411	29	[	[	X
dpc-2653	411	30	77	77	NUM
dpc-2653	411	31	]	]	PUNCT
dpc-2653	411	32	.	.	PUNCT
dpc-2653	412	1	conclusions	conclusion	NOUN
dpc-2653	412	2	a	a	DET
dpc-2653	412	3	wide	wide	ADJ
dpc-2653	412	4	spectrum	spectrum	NOUN
dpc-2653	412	5	of	of	ADP
dpc-2653	412	6	nail	nail	NOUN
dpc-2653	412	7	toxicities	toxicity	NOUN
dpc-2653	412	8	has	have	AUX
dpc-2653	412	9	so	so	ADV
dpc-2653	412	10	far	far	ADV
dpc-2653	412	11	been	be	AUX
dpc-2653	412	12	described	describe	VERB
dpc-2653	412	13	in	in	ADP
dpc-2653	412	14	association	association	NOUN
dpc-2653	412	15	with	with	ADP
dpc-2653	412	16	both	both	PRON
dpc-2653	412	17	,	,	PUNCT
dpc-2653	412	18	conventional	conventional	ADJ
dpc-2653	412	19	and	and	CCONJ
dpc-2653	412	20	newer	new	ADJ
dpc-2653	412	21	anticancer	anticancer	NOUN
dpc-2653	412	22	agents	agent	NOUN
dpc-2653	412	23	;	;	PUNCT
dpc-2653	412	24	however	however	ADV
dpc-2653	412	25	,	,	PUNCT
dpc-2653	412	26	less	less	ADJ
dpc-2653	412	27	importance	importance	NOUN
dpc-2653	412	28	has	have	AUX
dpc-2653	412	29	been	be	AUX
dpc-2653	412	30	given	give	VERB
dpc-2653	412	31	to	to	ADP
dpc-2653	412	32	nail	nail	NOUN
dpc-2653	412	33	changes	change	NOUN
dpc-2653	412	34	as	as	ADP
dpc-2653	412	35	compared	compare	VERB
dpc-2653	412	36	to	to	ADP
dpc-2653	412	37	other	other	ADJ
dpc-2653	412	38	skin	skin	NOUN
dpc-2653	412	39	toxicities	toxicity	NOUN
dpc-2653	412	40	.	.	PUNCT
dpc-2653	413	1	considering	consider	VERB
dpc-2653	413	2	that	that	SCONJ
dpc-2653	413	3	nail	nail	NOUN
dpc-2653	413	4	toxicity	toxicity	NOUN
dpc-2653	413	5	is	be	AUX
dpc-2653	413	6	indeed	indeed	ADV
dpc-2653	413	7	almost	almost	ADV
dpc-2653	413	8	never	never	ADV
dpc-2653	413	9	life	life	NOUN
dpc-2653	413	10	-	-	PUNCT
dpc-2653	413	11	threatening	threatening	ADJ
dpc-2653	413	12	,	,	PUNCT
dpc-2653	413	13	discontinuation	discontinuation	NOUN
dpc-2653	413	14	of	of	ADP
dpc-2653	413	15	oncologic	oncologic	NOUN
dpc-2653	413	16	therapy	therapy	NOUN
dpc-2653	413	17	is	be	AUX
dpc-2653	413	18	only	only	ADV
dpc-2653	413	19	rarely	rarely	ADV
dpc-2653	413	20	necessary	necessary	ADJ
dpc-2653	413	21	.	.	PUNCT
dpc-2653	414	1	however	however	ADV
dpc-2653	414	2	,	,	PUNCT
dpc-2653	414	3	drug	drug	NOUN
dpc-2653	414	4	interruptions	interruption	NOUN
dpc-2653	414	5	or	or	CCONJ
dpc-2653	414	6	dose	dose	NOUN
dpc-2653	414	7	modifications	modification	NOUN
dpc-2653	414	8	may	may	AUX
dpc-2653	414	9	be	be	AUX
dpc-2653	414	10	warranted	warrant	VERB
dpc-2653	414	11	,	,	PUNCT
dpc-2653	414	12	mostly	mostly	ADV
dpc-2653	414	13	due	due	ADJ
dpc-2653	414	14	to	to	ADP
dpc-2653	414	15	serious	serious	ADJ
dpc-2653	414	16	impairment	impairment	NOUN
dpc-2653	414	17	of	of	ADP
dpc-2653	414	18	patients	patient	NOUN
dpc-2653	414	19	’	'	PUNCT
dpc-2653	414	20	quality	quality	NOUN
dpc-2653	414	21	of	of	ADP
dpc-2653	414	22	life	life	NOUN
dpc-2653	414	23	.	.	PUNCT
dpc-2653	415	1	management	management	NOUN
dpc-2653	415	2	is	be	AUX
dpc-2653	415	3	primarily	primarily	ADV
dpc-2653	415	4	directed	direct	VERB
dpc-2653	415	5	at	at	ADP
dpc-2653	415	6	symptom	symptom	NOUN
dpc-2653	415	7	control	control	NOUN
dpc-2653	415	8	and	and	CCONJ
dpc-2653	415	9	relief	relief	NOUN
dpc-2653	415	10	of	of	ADP
dpc-2653	415	11	the	the	DET
dpc-2653	415	12	patient	patient	NOUN
dpc-2653	415	13	.	.	PUNCT
dpc-2653	416	1	nail	nail	NOUN
dpc-2653	416	2	changes	change	NOUN
dpc-2653	416	3	that	that	PRON
dpc-2653	416	4	result	result	VERB
dpc-2653	416	5	from	from	ADP
dpc-2653	416	6	matrix	matrix	NOUN
dpc-2653	416	7	interruption	interruption	NOUN
dpc-2653	416	8	of	of	ADP
dpc-2653	416	9	blood	blood	NOUN
dpc-2653	416	10	flow	flow	NOUN
dpc-2653	416	11	often	often	ADV
dpc-2653	416	12	induce	induce	VERB
dpc-2653	416	13	cosmetic	cosmetic	ADJ
dpc-2653	416	14	changes	change	NOUN
dpc-2653	416	15	(	(	PUNCT
dpc-2653	416	16	not	not	PART
dpc-2653	416	17	requiring	require	VERB
dpc-2653	416	18	intervention	intervention	NOUN
dpc-2653	416	19	)	)	PUNCT
dpc-2653	416	20	,	,	PUNCT
dpc-2653	416	21	with	with	ADP
dpc-2653	416	22	the	the	DET
dpc-2653	416	23	nail	nail	NOUN
dpc-2653	416	24	eventually	eventually	ADV
dpc-2653	416	25	growing	grow	VERB
dpc-2653	416	26	out	out	ADP
dpc-2653	416	27	normally	normally	ADV
dpc-2653	416	28	after	after	ADP
dpc-2653	416	29	treatment	treatment	NOUN
dpc-2653	416	30	discontinuation	discontinuation	NOUN
dpc-2653	416	31	.	.	PUNCT
dpc-2653	417	1	on	on	ADP
dpc-2653	417	2	the	the	DET
dpc-2653	417	3	other	other	ADJ
dpc-2653	417	4	hand	hand	NOUN
dpc-2653	417	5	,	,	PUNCT
dpc-2653	417	6	nail	nail	NOUN
dpc-2653	417	7	changes	change	NOUN
dpc-2653	417	8	due	due	ADJ
dpc-2653	417	9	to	to	ADP
dpc-2653	417	10	disruption	disruption	NOUN
dpc-2653	417	11	of	of	ADP
dpc-2653	417	12	the	the	DET
dpc-2653	417	13	nail	nail	NOUN
dpc-2653	417	14	folds	fold	NOUN
dpc-2653	417	15	frequently	frequently	ADV
dpc-2653	417	16	require	require	VERB
dpc-2653	417	17	therapeutic	therapeutic	ADJ
dpc-2653	417	18	intervention	intervention	NOUN
dpc-2653	417	19	,	,	PUNCT
dpc-2653	417	20	and	and	CCONJ
dpc-2653	417	21	depending	depend	VERB
dpc-2653	417	22	on	on	ADP
dpc-2653	417	23	the	the	DET
dpc-2653	417	24	severity	severity	NOUN
dpc-2653	417	25	,	,	PUNCT
dpc-2653	417	26	also	also	ADV
dpc-2653	417	27	dose	dose	VERB
dpc-2653	417	28	modifications	modification	NOUN
dpc-2653	417	29	.	.	PUNCT
dpc-2653	418	1	hematoma	hematoma	NOUN
dpc-2653	418	2	or	or	CCONJ
dpc-2653	418	3	subungual	subungual	ADJ
dpc-2653	418	4	abscess	abscess	NOUN
dpc-2653	418	5	[	[	X
dpc-2653	418	6	7	7	NUM
dpc-2653	418	7	]	]	PUNCT
dpc-2653	418	8	.	.	PUNCT
dpc-2653	419	1	the	the	DET
dpc-2653	419	2	nail	nail	NOUN
dpc-2653	419	3	bed	bed	NOUN
dpc-2653	419	4	should	should	AUX
dpc-2653	419	5	be	be	AUX
dpc-2653	419	6	cleaned	clean	VERB
dpc-2653	419	7	and	and	CCONJ
dpc-2653	419	8	a	a	DET
dpc-2653	419	9	sample	sample	NOUN
dpc-2653	419	10	for	for	ADP
dpc-2653	419	11	culture	culture	NOUN
dpc-2653	419	12	collected	collect	VERB
dpc-2653	419	13	at	at	ADP
dpc-2653	419	14	the	the	DET
dpc-2653	419	15	same	same	ADJ
dpc-2653	419	16	time	time	NOUN
dpc-2653	419	17	,	,	PUNCT
dpc-2653	419	18	and	and	CCONJ
dpc-2653	419	19	in	in	ADP
dpc-2653	419	20	case	case	NOUN
dpc-2653	419	21	of	of	ADP
dpc-2653	419	22	suspected	suspect	VERB
dpc-2653	419	23	infection	infection	NOUN
dpc-2653	419	24	should	should	AUX
dpc-2653	419	25	be	be	AUX
dpc-2653	419	26	also	also	ADV
dpc-2653	419	27	promptly	promptly	ADV
dpc-2653	419	28	treated	treat	VERB
dpc-2653	419	29	with	with	ADP
dpc-2653	419	30	topical	topical	ADJ
dpc-2653	419	31	/	/	SYM
dpc-2653	419	32	oral	oral	ADJ
dpc-2653	419	33	antibiotics	antibiotic	NOUN
dpc-2653	419	34	antiviral	antiviral	NOUN
dpc-2653	419	35	or	or	CCONJ
dpc-2653	419	36	antifungal	antifungal	ADJ
dpc-2653	419	37	therapy	therapy	NOUN
dpc-2653	420	1	[	[	X
dpc-2653	420	2	48	48	NUM
dpc-2653	420	3	]	]	PUNCT
dpc-2653	420	4	.	.	PUNCT
dpc-2653	421	1	the	the	DET
dpc-2653	421	2	detached	detach	VERB
dpc-2653	421	3	nails	nail	NOUN
dpc-2653	421	4	should	should	AUX
dpc-2653	421	5	be	be	AUX
dpc-2653	421	6	cut	cut	VERB
dpc-2653	421	7	regularly	regularly	ADV
dpc-2653	421	8	until	until	SCONJ
dpc-2653	421	9	the	the	DET
dpc-2653	421	10	nail	nail	NOUN
dpc-2653	421	11	plate	plate	NOUN
dpc-2653	421	12	grows	grow	VERB
dpc-2653	421	13	and	and	CCONJ
dpc-2653	421	14	covers	cover	VERB
dpc-2653	421	15	the	the	DET
dpc-2653	421	16	nail	nail	NOUN
dpc-2653	421	17	bed	bed	NOUN
dpc-2653	421	18	.	.	PUNCT
dpc-2653	422	1	in	in	ADP
dpc-2653	422	2	the	the	DET
dpc-2653	422	3	setting	setting	NOUN
dpc-2653	422	4	of	of	ADP
dpc-2653	422	5	paronychia	paronychia	NOUN
dpc-2653	422	6	without	without	ADP
dpc-2653	422	7	infection	infection	NOUN
dpc-2653	422	8	,	,	PUNCT
dpc-2653	422	9	potent	potent	ADJ
dpc-2653	422	10	topical	topical	ADJ
dpc-2653	422	11	steroids	steroid	NOUN
dpc-2653	422	12	are	be	AUX
dpc-2653	422	13	recommended	recommend	VERB
dpc-2653	422	14	.	.	PUNCT
dpc-2653	423	1	except	except	SCONJ
dpc-2653	423	2	for	for	ADP
dpc-2653	423	3	the	the	DET
dpc-2653	423	4	aforementioned	aforementioned	ADJ
dpc-2653	423	5	traditional	traditional	ADJ
dpc-2653	423	6	management	management	NOUN
dpc-2653	423	7	modalities	modality	NOUN
dpc-2653	423	8	,	,	PUNCT
dpc-2653	423	9	some	some	DET
dpc-2653	423	10	other	other	ADJ
dpc-2653	423	11	clinical	clinical	ADJ
dpc-2653	423	12	methods	method	NOUN
dpc-2653	423	13	,	,	PUNCT
dpc-2653	423	14	such	such	ADJ
dpc-2653	423	15	as	as	ADP
dpc-2653	423	16	cryotherapy	cryotherapy	NOUN
dpc-2653	423	17	and	and	CCONJ
dpc-2653	423	18	nail	nail	NOUN
dpc-2653	423	19	solution	solution	NOUN
dpc-2653	423	20	(	(	PUNCT
dpc-2653	423	21	nail	nail	NOUN
dpc-2653	423	22	balm	balm	NOUN
dpc-2653	423	23	)	)	PUNCT
dpc-2653	423	24	,	,	PUNCT
dpc-2653	423	25	have	have	AUX
dpc-2653	423	26	been	be	AUX
dpc-2653	423	27	reported	report	VERB
dpc-2653	423	28	and	and	CCONJ
dpc-2653	423	29	promoted	promote	VERB
dpc-2653	423	30	.	.	PUNCT
dpc-2653	424	1	huang	huang	PROPN
dpc-2653	424	2	et	et	PROPN
dpc-2653	424	3	al	al	PROPN
dpc-2653	424	4	.	.	PUNCT
dpc-2653	425	1	[	[	X
dpc-2653	425	2	77	77	NUM
dpc-2653	425	3	]	]	PUNCT
dpc-2653	425	4	in	in	ADP
dpc-2653	425	5	their	their	PRON
dpc-2653	425	6	meta	meta	ADJ
dpc-2653	425	7	-	-	PUNCT
dpc-2653	425	8	analysis	analysis	NOUN
dpc-2653	425	9	revealed	reveal	VERB
dpc-2653	425	10	that	that	SCONJ
dpc-2653	425	11	both	both	PRON
dpc-2653	425	12	nail	nail	NOUN
dpc-2653	425	13	solution	solution	NOUN
dpc-2653	425	14	-	-	PUNCT
dpc-2653	425	15	based	base	VERB
dpc-2653	425	16	and	and	CCONJ
dpc-2653	425	17	cryotherapy	cryotherapy	NOUN
dpc-2653	425	18	-	-	PUNCT
dpc-2653	425	19	based	base	VERB
dpc-2653	425	20	prophylactic	prophylactic	ADJ
dpc-2653	425	21	management	management	NOUN
dpc-2653	425	22	(	(	PUNCT
dpc-2653	425	23	frozen	frozen	ADJ
dpc-2653	425	24	gloves	glove	NOUN
dpc-2653	425	25	,	,	PUNCT
dpc-2653	425	26	frozen	frozen	ADJ
dpc-2653	425	27	socks	sock	NOUN
dpc-2653	425	28	and	and	CCONJ
dpc-2653	425	29	ice	ice	NOUN
dpc-2653	425	30	packs	pack	NOUN
dpc-2653	425	31	)	)	PUNCT
dpc-2653	425	32	were	be	AUX
dpc-2653	425	33	effective	effective	ADJ
dpc-2653	425	34	for	for	ADP
dpc-2653	425	35	treating	treat	VERB
dpc-2653	425	36	taxane	taxane	NOUN
dpc-2653	425	37	-	-	PUNCT
dpc-2653	425	38	induced	induce	VERB
dpc-2653	425	39	nail	nail	NOUN
dpc-2653	425	40	toxicity	toxicity	NOUN
dpc-2653	425	41	.	.	PUNCT
dpc-2653	426	1	nail	nail	NOUN
dpc-2653	426	2	solution	solution	NOUN
dpc-2653	426	3	use	use	NOUN
dpc-2653	426	4	is	be	AUX
dpc-2653	426	5	known	know	VERB
dpc-2653	426	6	to	to	PART
dpc-2653	426	7	reduce	reduce	VERB
dpc-2653	426	8	the	the	DET
dpc-2653	426	9	levels	level	NOUN
dpc-2653	426	10	of	of	ADP
dpc-2653	426	11	substance	substance	NOUN
dpc-2653	426	12	p	p	NOUN
dpc-2653	426	13	,	,	PUNCT
dpc-2653	426	14	a	a	DET
dpc-2653	426	15	neurotransmitter	neurotransmitter	NOUN
dpc-2653	426	16	that	that	PRON
dpc-2653	426	17	induces	induce	VERB
dpc-2653	426	18	inflammation	inflammation	NOUN
dpc-2653	426	19	,	,	PUNCT
dpc-2653	426	20	which	which	PRON
dpc-2653	426	21	adversely	adversely	ADV
dpc-2653	426	22	affects	affect	VERB
dpc-2653	426	23	nails	nail	NOUN
dpc-2653	426	24	[	[	X
dpc-2653	426	25	78	78	NUM
dpc-2653	426	26	]	]	PUNCT
dpc-2653	426	27	.	.	PUNCT
dpc-2653	427	1	moreover	moreover	ADV
dpc-2653	427	2	,	,	PUNCT
dpc-2653	427	3	plant	plant	NOUN
dpc-2653	427	4	-	-	PUNCT
dpc-2653	427	5	based	base	VERB
dpc-2653	427	6	waxes	wax	NOUN
dpc-2653	427	7	and	and	CCONJ
dpc-2653	427	8	essential	essential	ADJ
dpc-2653	427	9	oils	oil	NOUN
dpc-2653	427	10	are	be	AUX
dpc-2653	427	11	naturally	naturally	ADV
dpc-2653	427	12	rich	rich	ADJ
dpc-2653	427	13	in	in	ADP
dpc-2653	427	14	phytochemicals	phytochemical	NOUN
dpc-2653	427	15	,	,	PUNCT
dpc-2653	427	16	particularly	particularly	ADV
dpc-2653	427	17	phenolic	phenolic	ADJ
dpc-2653	427	18	polyphenols	polyphenol	NOUN
dpc-2653	427	19	,	,	PUNCT
dpc-2653	427	20	which	which	PRON
dpc-2653	427	21	have	have	AUX
dpc-2653	427	22	been	be	AUX
dpc-2653	427	23	reported	report	VERB
dpc-2653	427	24	to	to	PART
dpc-2653	427	25	exhibit	exhibit	VERB
dpc-2653	427	26	antioxidant	antioxidant	ADJ
dpc-2653	427	27	,	,	PUNCT
dpc-2653	427	28	anti	anti	ADJ
dpc-2653	427	29	-	-	ADJ
dpc-2653	427	30	inflammatory	inflammatory	ADJ
dpc-2653	427	31	,	,	PUNCT
dpc-2653	427	32	dna	dna	PROPN
dpc-2653	427	33	repair	repair	NOUN
dpc-2653	427	34	-	-	PUNCT
dpc-2653	427	35	enhancing	enhance	VERB
dpc-2653	427	36	and	and	CCONJ
dpc-2653	427	37	antimicrobial	antimicrobial	ADJ
dpc-2653	427	38	properties	property	NOUN
dpc-2653	427	39	[	[	X
dpc-2653	427	40	79	79	NUM
dpc-2653	427	41	,	,	PUNCT
dpc-2653	427	42	80	80	NUM
dpc-2653	427	43	]	]	PUNCT
dpc-2653	427	44	.	.	PUNCT
dpc-2653	428	1	in	in	ADP
dpc-2653	428	2	addition	addition	NOUN
dpc-2653	428	3	to	to	ADP
dpc-2653	428	4	their	their	PRON
dpc-2653	428	5	abilities	ability	NOUN
dpc-2653	428	6	to	to	PART
dpc-2653	428	7	moisturize	moisturize	VERB
dpc-2653	428	8	the	the	DET
dpc-2653	428	9	skin	skin	NOUN
dpc-2653	428	10	and	and	CCONJ
dpc-2653	428	11	prevent	prevent	VERB
dpc-2653	428	12	the	the	DET
dpc-2653	428	13	drying	dry	VERB
dpc-2653	428	14	and	and	CCONJ
dpc-2653	428	15	splitting	splitting	NOUN
dpc-2653	428	16	of	of	ADP
dpc-2653	428	17	nails	nail	NOUN
dpc-2653	428	18	,	,	PUNCT
dpc-2653	428	19	the	the	DET
dpc-2653	428	20	waxes	wax	NOUN
dpc-2653	428	21	and	and	CCONJ
dpc-2653	428	22	essential	essential	ADJ
dpc-2653	428	23	oils	oil	NOUN
dpc-2653	428	24	were	be	AUX
dpc-2653	428	25	hypothesized	hypothesize	VERB
dpc-2653	428	26	to	to	PART
dpc-2653	428	27	be	be	AUX
dpc-2653	428	28	sufficiently	sufficiently	ADV
dpc-2653	428	29	absorbed	absorb	VERB
dpc-2653	428	30	into	into	ADP
dpc-2653	428	31	the	the	DET
dpc-2653	428	32	nail	nail	NOUN
dpc-2653	428	33	beds	bed	NOUN
dpc-2653	428	34	to	to	PART
dpc-2653	428	35	act	act	VERB
dpc-2653	428	36	as	as	ADP
dpc-2653	428	37	local	local	ADJ
dpc-2653	428	38	antidotes	antidote	NOUN
dpc-2653	428	39	to	to	ADP
dpc-2653	428	40	the	the	DET
dpc-2653	428	41	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	428	42	agent	agent	NOUN
dpc-2653	428	43	,	,	PUNCT
dpc-2653	428	44	thus	thus	ADV
dpc-2653	428	45	preventing	prevent	VERB
dpc-2653	428	46	damage	damage	NOUN
dpc-2653	428	47	to	to	ADP
dpc-2653	428	48	the	the	DET
dpc-2653	428	49	proliferating	proliferate	VERB
dpc-2653	428	50	stem	stem	NOUN
dpc-2653	428	51	cells	cell	NOUN
dpc-2653	428	52	,	,	PUNCT
dpc-2653	428	53	avoiding	avoid	VERB
dpc-2653	428	54	secondary	secondary	ADJ
dpc-2653	428	55	damage	damage	NOUN
dpc-2653	428	56	from	from	ADP
dpc-2653	428	57	inflammation	inflammation	NOUN
dpc-2653	428	58	or	or	CCONJ
dpc-2653	428	59	secondary	secondary	ADJ
dpc-2653	428	60	infection	infection	NOUN
dpc-2653	428	61	as	as	ADV
dpc-2653	428	62	well	well	ADV
dpc-2653	428	63	as	as	ADP
dpc-2653	428	64	delaying	delay	VERB
dpc-2653	428	65	the	the	DET
dpc-2653	428	66	time	time	NOUN
dpc-2653	428	67	to	to	ADP
dpc-2653	428	68	nail	nail	VERB
dpc-2653	428	69	toxicity	toxicity	NOUN
dpc-2653	428	70	[	[	X
dpc-2653	428	71	79	79	NUM
dpc-2653	428	72	,	,	PUNCT
dpc-2653	428	73	80	80	NUM
dpc-2653	428	74	]	]	PUNCT
dpc-2653	428	75	.	.	PUNCT
dpc-2653	429	1	figure	figure	NOUN
dpc-2653	429	2	4	4	NUM
dpc-2653	429	3	.	.	PUNCT
dpc-2653	429	4	a.	a.	NOUN
dpc-2653	429	5	onycholysis	onycholysis	NOUN
dpc-2653	429	6	due	due	ADP
dpc-2653	429	7	to	to	ADP
dpc-2653	429	8	taxane	taxane	NOUN
dpc-2653	429	9	treatment	treatment	NOUN
dpc-2653	429	10	.	.	PUNCT
dpc-2653	430	1	observe	observe	VERB
dpc-2653	430	2	important	important	ADJ
dpc-2653	430	3	detachment	detachment	NOUN
dpc-2653	430	4	of	of	ADP
dpc-2653	430	5	plate	plate	NOUN
dpc-2653	430	6	from	from	ADP
dpc-2653	430	7	bed	bed	NOUN
dpc-2653	430	8	and	and	CCONJ
dpc-2653	430	9	presence	presence	NOUN
dpc-2653	430	10	of	of	ADP
dpc-2653	430	11	purulent	purulent	ADJ
dpc-2653	430	12	discharge	discharge	NOUN
dpc-2653	430	13	,	,	PUNCT
dpc-2653	430	14	b.	b.	NOUN
dpc-2653	430	15	clipping	clipping	NOUN
dpc-2653	430	16	of	of	ADP
dpc-2653	430	17	the	the	DET
dpc-2653	430	18	onycholytic	onycholytic	ADJ
dpc-2653	430	19	part	part	NOUN
dpc-2653	430	20	of	of	ADP
dpc-2653	430	21	the	the	DET
dpc-2653	430	22	nails	nail	NOUN
dpc-2653	430	23	relieves	relieve	VERB
dpc-2653	430	24	pain	pain	NOUN
dpc-2653	430	25	and	and	CCONJ
dpc-2653	430	26	allows	allow	VERB
dpc-2653	430	27	for	for	ADP
dpc-2653	430	28	better	well	ADJ
dpc-2653	430	29	hygiene	hygiene	NOUN
dpc-2653	430	30	.	.	PUNCT
dpc-2653	431	1	16	16	NUM
dpc-2653	431	2	review	review	NOUN
dpc-2653	431	3	|	|	ADV
dpc-2653	431	4	dermatol	dermatol	ADJ
dpc-2653	431	5	pract	pract	NOUN
dpc-2653	431	6	concept	concept	NOUN
dpc-2653	431	7	.	.	PUNCT
dpc-2653	432	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	432	2	14	14	NUM
dpc-2653	432	3	.	.	PUNCT
dpc-2653	433	1	dasanu	dasanu	PROPN
dpc-2653	433	2	ca	can	AUX
dpc-2653	433	3	,	,	PUNCT
dpc-2653	433	4	wiernik	wiernik	VERB
dpc-2653	433	5	ph	ph	PROPN
dpc-2653	433	6	,	,	PUNCT
dpc-2653	433	7	vaillant	vaillant	PROPN
dpc-2653	433	8	j	j	PROPN
dpc-2653	433	9	,	,	PUNCT
dpc-2653	433	10	alexandrescu	alexandrescu	NOUN
dpc-2653	433	11	dt	dt	PROPN
dpc-2653	433	12	.	.	PUNCT
dpc-2653	434	1	a	a	DET
dpc-2653	434	2	complex	complex	ADJ
dpc-2653	434	3	pattern	pattern	NOUN
dpc-2653	434	4	of	of	ADP
dpc-2653	434	5	melanonychia	melanonychia	NOUN
dpc-2653	434	6	and	and	CCONJ
dpc-2653	434	7	onycholysis	onycholysis	NOUN
dpc-2653	434	8	after	after	ADP
dpc-2653	434	9	treatment	treatment	NOUN
dpc-2653	434	10	with	with	ADP
dpc-2653	434	11	pemetrexed	pemetrexed	NOUN
dpc-2653	434	12	for	for	ADP
dpc-2653	434	13	lung	lung	NOUN
dpc-2653	434	14	cancer	cancer	NOUN
dpc-2653	434	15	.	.	PUNCT
dpc-2653	435	1	skinmed	skinme	VERB
dpc-2653	435	2	.	.	PUNCT
dpc-2653	436	1	2007;6(2):95–6	2007;6(2):95–6	NOUN
dpc-2653	436	2	.	.	PUNCT
dpc-2653	437	1	15	15	NUM
dpc-2653	437	2	.	.	PUNCT
dpc-2653	437	3	malet	malet	PROPN
dpc-2653	437	4	-	-	PUNCT
dpc-2653	437	5	martino	martino	PROPN
dpc-2653	437	6	m	m	PROPN
dpc-2653	437	7	,	,	PUNCT
dpc-2653	437	8	martino	martino	PROPN
dpc-2653	437	9	r.	r.	PROPN
dpc-2653	437	10	clinical	clinical	PROPN
dpc-2653	437	11	studies	study	NOUN
dpc-2653	437	12	of	of	ADP
dpc-2653	437	13	three	three	NUM
dpc-2653	437	14	oral	oral	ADJ
dpc-2653	437	15	prodrugs	prodrug	NOUN
dpc-2653	437	16	of	of	ADP
dpc-2653	437	17	5	5	NUM
dpc-2653	437	18	-	-	PUNCT
dpc-2653	437	19	fluorouracil	fluorouracil	NOUN
dpc-2653	437	20	(	(	PUNCT
dpc-2653	437	21	capecitabine	capecitabine	NOUN
dpc-2653	437	22	,	,	PUNCT
dpc-2653	437	23	uft	uft	PROPN
dpc-2653	437	24	,	,	PUNCT
dpc-2653	437	25	s-1	s-1	PROPN
dpc-2653	437	26	):	):	PUNCT
dpc-2653	437	27	a	a	DET
dpc-2653	437	28	review	review	NOUN
dpc-2653	437	29	.	.	PUNCT
dpc-2653	438	1	vol	vol	NOUN
dpc-2653	438	2	.	.	PROPN
dpc-2653	438	3	7	7	NUM
dpc-2653	438	4	,	,	PUNCT
dpc-2653	438	5	the	the	DET
dpc-2653	438	6	oncologist	oncologist	NOUN
dpc-2653	438	7	.	.	PUNCT
dpc-2653	439	1	2002	2002	NUM
dpc-2653	439	2	.	.	PUNCT
dpc-2653	440	1	p.	p.	NOUN
dpc-2653	440	2	288–323	288–323	NUM
dpc-2653	440	3	.	.	PUNCT
dpc-2653	441	1	16	16	NUM
dpc-2653	441	2	.	.	PUNCT
dpc-2653	442	1	valks	valks	PROPN
dpc-2653	442	2	r	r	NOUN
dpc-2653	442	3	,	,	PUNCT
dpc-2653	442	4	garcia	garcia	PROPN
dpc-2653	442	5	-	-	PUNCT
dpc-2653	442	6	diez	diez	PROPN
dpc-2653	442	7	a	a	PRON
dpc-2653	442	8	,	,	PUNCT
dpc-2653	442	9	fernandez	fernandez	PROPN
dpc-2653	442	10	-	-	PUNCT
dpc-2653	442	11	herrera	herrera	NOUN
dpc-2653	442	12	j.	j.	PROPN
dpc-2653	442	13	mucocutaneous	mucocutaneous	ADJ
dpc-2653	442	14	reactions	reaction	NOUN
dpc-2653	442	15	to	to	PART
dpc-2653	442	16	chemotherapy	chemotherapy	NOUN
dpc-2653	442	17	[	[	X
dpc-2653	442	18	3	3	NUM
dpc-2653	442	19	]	]	PUNCT
dpc-2653	442	20	.	.	PUNCT
dpc-2653	443	1	j	j	PROPN
dpc-2653	443	2	am	be	AUX
dpc-2653	443	3	acad	acad	ADJ
dpc-2653	443	4	dermatol	dermatol	NOUN
dpc-2653	443	5	.	.	PUNCT
dpc-2653	444	1	2000;42(4):699	2000;42(4):699	NOUN
dpc-2653	444	2	.	.	PUNCT
dpc-2653	445	1	17	17	NUM
dpc-2653	445	2	.	.	PUNCT
dpc-2653	446	1	yamamoto	yamamoto	PROPN
dpc-2653	446	2	t.	t.	PROPN
dpc-2653	446	3	bleomycin	bleomycin	PROPN
dpc-2653	446	4	and	and	CCONJ
dpc-2653	446	5	the	the	DET
dpc-2653	446	6	skin	skin	NOUN
dpc-2653	446	7	.	.	PUNCT
dpc-2653	447	1	br	br	PROPN
dpc-2653	447	2	j	j	PROPN
dpc-2653	447	3	dermatol	dermatol	NOUN
dpc-2653	447	4	.	.	PUNCT
dpc-2653	448	1	2006;155(5):869–75	2006;155(5):869–75	X
dpc-2653	448	2	.	.	NOUN
dpc-2653	448	3	18	18	NUM
dpc-2653	448	4	.	.	PUNCT
dpc-2653	449	1	turan	turan	PROPN
dpc-2653	449	2	erkek	erkek	PROPN
dpc-2653	449	3	e	e	PROPN
dpc-2653	449	4	,	,	PUNCT
dpc-2653	449	5	karaali	karaali	PROPN
dpc-2653	449	6	cn	cn	PROPN
dpc-2653	449	7	,	,	PUNCT
dpc-2653	449	8	yılmaz	yılmaz	PROPN
dpc-2653	449	9	g	g	PROPN
dpc-2653	449	10	,	,	PUNCT
dpc-2653	449	11	gültürk	gültürk	PROPN
dpc-2653	449	12	e.	e.	PROPN
dpc-2653	449	13	bleomycin	bleomycin	PROPN
dpc-2653	449	14	-	-	PUNCT
dpc-2653	449	15	induced	induce	VERB
dpc-2653	449	16	flagellate	flagellate	NOUN
dpc-2653	449	17	dermatitis	dermatitis	NOUN
dpc-2653	449	18	.	.	PUNCT
dpc-2653	450	1	turkish	turkish	ADJ
dpc-2653	450	2	j	j	PROPN
dpc-2653	450	3	haematol	haematol	NOUN
dpc-2653	450	4	off	off	ADP
dpc-2653	450	5	j	j	PROPN
dpc-2653	450	6	turkish	turkish	ADJ
dpc-2653	450	7	soc	soc	NOUN
dpc-2653	450	8	haematol	haematol	NOUN
dpc-2653	450	9	.	.	PUNCT
dpc-2653	451	1	2019;36(2):138–40	2019;36(2):138–40	NUM
dpc-2653	451	2	.	.	NOUN
dpc-2653	451	3	19	19	NUM
dpc-2653	451	4	.	.	PUNCT
dpc-2653	451	5	cortes	corte	VERB
dpc-2653	451	6	je	je	PROPN
dpc-2653	451	7	,	,	PUNCT
dpc-2653	451	8	pazdur	pazdur	PROPN
dpc-2653	451	9	r.	r.	PROPN
dpc-2653	451	10	docetaxel	docetaxel	PROPN
dpc-2653	451	11	.	.	PUNCT
dpc-2653	452	1	j	j	PROPN
dpc-2653	452	2	clin	clin	PROPN
dpc-2653	452	3	oncol	oncol	PROPN
dpc-2653	452	4	.	.	PUNCT
dpc-2653	453	1	1995;13(10):2643–55	1995;13(10):2643–55	NUM
dpc-2653	453	2	.	.	X
dpc-2653	454	1	20	20	NUM
dpc-2653	454	2	.	.	PUNCT
dpc-2653	455	1	gelmon	gelmon	PROPN
dpc-2653	455	2	k.	k.	PROPN
dpc-2653	456	1	the	the	DET
dpc-2653	456	2	taxoids	taxoids	PROPN
dpc-2653	456	3	:	:	PUNCT
dpc-2653	456	4	paclitaxel	paclitaxel	PROPN
dpc-2653	456	5	and	and	CCONJ
dpc-2653	456	6	docetaxel	docetaxel	PROPN
dpc-2653	456	7	.	.	PUNCT
dpc-2653	457	1	lancet	lancet	PROPN
dpc-2653	457	2	.	.	PUNCT
dpc-2653	458	1	1994;344(8932):1267–72	1994;344(8932):1267–72	ADJ
dpc-2653	458	2	.	.	PUNCT
dpc-2653	459	1	21	21	NUM
dpc-2653	459	2	.	.	PUNCT
dpc-2653	459	3	von	von	PROPN
dpc-2653	459	4	hoff	hoff	PROPN
dpc-2653	459	5	dd	dd	PROPN
dpc-2653	459	6	,	,	PUNCT
dpc-2653	459	7	ervin	ervin	PROPN
dpc-2653	459	8	t	t	PROPN
dpc-2653	459	9	,	,	PUNCT
dpc-2653	459	10	arena	arena	NOUN
dpc-2653	459	11	fp	fp	PROPN
dpc-2653	459	12	,	,	PUNCT
dpc-2653	459	13	chiorean	chiorean	PROPN
dpc-2653	459	14	eg	eg	PROPN
dpc-2653	459	15	,	,	PUNCT
dpc-2653	459	16	infante	infante	PROPN
dpc-2653	459	17	j	j	PROPN
dpc-2653	459	18	,	,	PUNCT
dpc-2653	459	19	moore	moore	PROPN
dpc-2653	459	20	m	m	PROPN
dpc-2653	459	21	,	,	PUNCT
dpc-2653	459	22	et	et	PROPN
dpc-2653	459	23	al	al	PROPN
dpc-2653	459	24	.	.	PROPN
dpc-2653	459	25	increased	increase	VERB
dpc-2653	459	26	survival	survival	NOUN
dpc-2653	459	27	in	in	ADP
dpc-2653	459	28	pancreatic	pancreatic	ADJ
dpc-2653	459	29	cancer	cancer	NOUN
dpc-2653	459	30	with	with	ADP
dpc-2653	459	31	nab	nab	NOUN
dpc-2653	459	32	-	-	PUNCT
dpc-2653	459	33	paclitaxel	paclitaxel	NOUN
dpc-2653	459	34	plus	plus	CCONJ
dpc-2653	459	35	gemcitabine	gemcitabine	NOUN
dpc-2653	459	36	.	.	PUNCT
dpc-2653	460	1	n	n	PROPN
dpc-2653	460	2	engl	engl	PROPN
dpc-2653	460	3	j	j	PROPN
dpc-2653	460	4	med	med	PROPN
dpc-2653	460	5	.	.	PUNCT
dpc-2653	461	1	2013;369(18):1691–703	2013;369(18):1691–703	X
dpc-2653	461	2	.	.	NOUN
dpc-2653	461	3	22	22	NUM
dpc-2653	461	4	.	.	PUNCT
dpc-2653	462	1	sibaud	sibaud	PROPN
dpc-2653	462	2	v	v	PROPN
dpc-2653	462	3	,	,	PUNCT
dpc-2653	462	4	leboeuf	leboeuf	NOUN
dpc-2653	462	5	nr	nr	PROPN
dpc-2653	462	6	,	,	PUNCT
dpc-2653	462	7	roche	roche	PROPN
dpc-2653	462	8	h	h	PROPN
dpc-2653	462	9	,	,	PUNCT
dpc-2653	462	10	belum	belum	PROPN
dpc-2653	462	11	vr	vr	PROPN
dpc-2653	462	12	,	,	PUNCT
dpc-2653	462	13	gladieff	gladieff	PROPN
dpc-2653	462	14	l	l	NOUN
dpc-2653	462	15	,	,	PUNCT
dpc-2653	462	16	deslandres	deslandre	VERB
dpc-2653	462	17	m	m	PROPN
dpc-2653	462	18	,	,	PUNCT
dpc-2653	462	19	et	et	PROPN
dpc-2653	462	20	al	al	PROPN
dpc-2653	462	21	.	.	PUNCT
dpc-2653	463	1	dermatological	dermatological	ADJ
dpc-2653	463	2	adverse	adverse	ADJ
dpc-2653	463	3	events	event	NOUN
dpc-2653	463	4	with	with	ADP
dpc-2653	463	5	taxane	taxane	NOUN
dpc-2653	463	6	chemotherapy	chemotherapy	NOUN
dpc-2653	463	7	.	.	PUNCT
dpc-2653	464	1	eur	eur	PROPN
dpc-2653	464	2	j	j	PROPN
dpc-2653	464	3	dermatology	dermatology	NOUN
dpc-2653	464	4	.	.	PUNCT
dpc-2653	465	1	2016;26(5):427–43	2016;26(5):427–43	X
dpc-2653	465	2	.	.	NOUN
dpc-2653	465	3	23	23	NUM
dpc-2653	465	4	.	.	PUNCT
dpc-2653	466	1	visual	visual	ADJ
dpc-2653	466	2	observations	observation	NOUN
dpc-2653	466	3	.	.	PUNCT
dpc-2653	467	1	science	science	NOUN
dpc-2653	467	2	(	(	PUNCT
dpc-2653	467	3	80-	80-	NUM
dpc-2653	467	4	)	)	PUNCT
dpc-2653	467	5	.	.	PUNCT
dpc-2653	468	1	2011;37:2010–1	2011;37:2010–1	X
dpc-2653	468	2	.	.	PROPN
dpc-2653	469	1	24	24	NUM
dpc-2653	469	2	.	.	PUNCT
dpc-2653	470	1	miller	miller	PROPN
dpc-2653	470	2	kk	kk	PROPN
dpc-2653	470	3	,	,	PUNCT
dpc-2653	470	4	gorcey	gorcey	PROPN
dpc-2653	470	5	l	l	PROPN
dpc-2653	470	6	,	,	PUNCT
dpc-2653	470	7	mclellan	mclellan	PROPN
dpc-2653	470	8	bn	bn	PROPN
dpc-2653	470	9	.	.	PUNCT
dpc-2653	470	10	chemotherapy	chemotherapy	NOUN
dpc-2653	470	11	-	-	ADJ
dpc-2653	470	12	induced	induce	VERB
dpc-2653	470	13	hand	hand	NOUN
dpc-2653	470	14	-	-	PUNCT
dpc-2653	470	15	foot	foot	NOUN
dpc-2653	470	16	syndrome	syndrome	NOUN
dpc-2653	470	17	and	and	CCONJ
dpc-2653	470	18	nail	nail	NOUN
dpc-2653	470	19	changes	change	NOUN
dpc-2653	470	20	:	:	PUNCT
dpc-2653	470	21	a	a	DET
dpc-2653	470	22	review	review	NOUN
dpc-2653	470	23	of	of	ADP
dpc-2653	470	24	clinical	clinical	ADJ
dpc-2653	470	25	presentation	presentation	NOUN
dpc-2653	470	26	,	,	PUNCT
dpc-2653	470	27	etiology	etiology	NOUN
dpc-2653	470	28	,	,	PUNCT
dpc-2653	470	29	pathogenesis	pathogenesis	NOUN
dpc-2653	470	30	,	,	PUNCT
dpc-2653	470	31	and	and	CCONJ
dpc-2653	470	32	management	management	NOUN
dpc-2653	470	33	.	.	PUNCT
dpc-2653	471	1	j	j	PROPN
dpc-2653	471	2	am	be	AUX
dpc-2653	471	3	acad	acad	X
dpc-2653	471	4	dermatol	dermatol	NOUN
dpc-2653	472	1	[	[	X
dpc-2653	472	2	internet	internet	NOUN
dpc-2653	472	3	]	]	PUNCT
dpc-2653	472	4	.	.	PUNCT
dpc-2653	473	1	2014;71(4):787–94	2014;71(4):787–94	X
dpc-2653	473	2	.	.	PUNCT
dpc-2653	473	3	available	available	ADJ
dpc-2653	473	4	from	from	ADP
dpc-2653	473	5	:	:	PUNCT
dpc-2653	473	6	http://	http://	PROPN
dpc-2653	473	7	dx.doi.org/10.1016/j.jaad.2014.03.019	dx.doi.org/10.1016/j.jaad.2014.03.019	PROPN
dpc-2653	473	8	25	25	NUM
dpc-2653	473	9	.	.	PUNCT
dpc-2653	474	1	scotté	scotté	PROPN
dpc-2653	474	2	f	f	PROPN
dpc-2653	474	3	,	,	PUNCT
dpc-2653	474	4	tourani	tourani	PROPN
dpc-2653	474	5	jm	jm	PROPN
dpc-2653	474	6	,	,	PUNCT
dpc-2653	474	7	banu	banu	PROPN
dpc-2653	474	8	e	e	NOUN
dpc-2653	474	9	,	,	PUNCT
dpc-2653	474	10	peyromaure	peyromaure	PROPN
dpc-2653	474	11	m	m	PROPN
dpc-2653	474	12	,	,	PUNCT
dpc-2653	474	13	levy	levy	NOUN
dpc-2653	474	14	e	e	NOUN
dpc-2653	474	15	,	,	PUNCT
dpc-2653	474	16	marsan	marsan	PROPN
dpc-2653	474	17	s	s	PROPN
dpc-2653	474	18	,	,	PUNCT
dpc-2653	474	19	et	et	PROPN
dpc-2653	474	20	al	al	PROPN
dpc-2653	474	21	.	.	PUNCT
dpc-2653	475	1	multicenter	multicenter	PROPN
dpc-2653	475	2	study	study	NOUN
dpc-2653	475	3	of	of	ADP
dpc-2653	475	4	a	a	DET
dpc-2653	475	5	frozen	frozen	ADJ
dpc-2653	475	6	glove	glove	NOUN
dpc-2653	475	7	to	to	PART
dpc-2653	475	8	prevent	prevent	VERB
dpc-2653	475	9	docetaxel	docetaxel	NOUN
dpc-2653	475	10	-	-	PUNCT
dpc-2653	475	11	induced	induce	VERB
dpc-2653	475	12	onycholysis	onycholysis	NOUN
dpc-2653	475	13	and	and	CCONJ
dpc-2653	475	14	cutaneous	cutaneous	ADJ
dpc-2653	475	15	toxicity	toxicity	NOUN
dpc-2653	475	16	of	of	ADP
dpc-2653	475	17	the	the	DET
dpc-2653	475	18	hand	hand	NOUN
dpc-2653	475	19	.	.	PUNCT
dpc-2653	476	1	j	j	PROPN
dpc-2653	476	2	clin	clin	PROPN
dpc-2653	476	3	oncol	oncol	PROPN
dpc-2653	476	4	.	.	PUNCT
dpc-2653	477	1	2005;23(19):4424–9	2005;23(19):4424–9	NUM
dpc-2653	477	2	.	.	NOUN
dpc-2653	477	3	26	26	NUM
dpc-2653	477	4	.	.	PUNCT
dpc-2653	478	1	minisini	minisini	PROPN
dpc-2653	478	2	am	am	PROPN
dpc-2653	478	3	,	,	PUNCT
dpc-2653	478	4	tosti	tosti	X
dpc-2653	478	5	a	a	PRON
dpc-2653	478	6	,	,	PUNCT
dpc-2653	478	7	sobrero	sobrero	PROPN
dpc-2653	478	8	af	af	PROPN
dpc-2653	478	9	,	,	PUNCT
dpc-2653	478	10	mansutti	mansutti	PROPN
dpc-2653	478	11	m	m	PROPN
dpc-2653	478	12	,	,	PUNCT
dpc-2653	478	13	piraccini	piraccini	PROPN
dpc-2653	478	14	bm	bm	PROPN
dpc-2653	478	15	,	,	PUNCT
dpc-2653	478	16	sacco	sacco	PROPN
dpc-2653	478	17	c	c	PROPN
dpc-2653	478	18	,	,	PUNCT
dpc-2653	478	19	et	et	PROPN
dpc-2653	478	20	al	al	PROPN
dpc-2653	478	21	.	.	PUNCT
dpc-2653	478	22	taxane	taxane	NOUN
dpc-2653	478	23	-	-	PUNCT
dpc-2653	478	24	induced	induce	VERB
dpc-2653	478	25	nail	nail	NOUN
dpc-2653	478	26	changes	change	NOUN
dpc-2653	478	27	:	:	PUNCT
dpc-2653	478	28	incidence	incidence	NOUN
dpc-2653	478	29	,	,	PUNCT
dpc-2653	478	30	clinical	clinical	ADJ
dpc-2653	478	31	presentation	presentation	NOUN
dpc-2653	478	32	and	and	CCONJ
dpc-2653	478	33	outcome	outcome	NOUN
dpc-2653	478	34	.	.	PUNCT
dpc-2653	479	1	ann	ann	PROPN
dpc-2653	479	2	oncol	oncol	PROPN
dpc-2653	479	3	.	.	PUNCT
dpc-2653	480	1	2003;14(2):333–7	2003;14(2):333–7	NUM
dpc-2653	480	2	.	.	PUNCT
dpc-2653	481	1	27	27	NUM
dpc-2653	481	2	.	.	PUNCT
dpc-2653	482	1	matsumoto	matsumoto	PROPN
dpc-2653	482	2	k	k	PROPN
dpc-2653	482	3	,	,	PUNCT
dpc-2653	482	4	hino	hino	PROPN
dpc-2653	482	5	c	c	X
dpc-2653	482	6	,	,	PUNCT
dpc-2653	482	7	fukuda	fukuda	PROPN
dpc-2653	482	8	k	k	PROPN
dpc-2653	482	9	,	,	PUNCT
dpc-2653	482	10	hamamoto	hamamoto	PROPN
dpc-2653	482	11	m	m	PROPN
dpc-2653	482	12	,	,	PUNCT
dpc-2653	482	13	tanioka	tanioka	PROPN
dpc-2653	482	14	m	m	PROPN
dpc-2653	482	15	,	,	PUNCT
dpc-2653	482	16	hirokaga	hirokaga	PROPN
dpc-2653	482	17	k	k	PROPN
dpc-2653	482	18	,	,	PUNCT
dpc-2653	482	19	et	et	PROPN
dpc-2653	482	20	al	al	PROPN
dpc-2653	482	21	.	.	PROPN
dpc-2653	482	22	prospective	prospective	ADJ
dpc-2653	482	23	study	study	NOUN
dpc-2653	482	24	of	of	ADP
dpc-2653	482	25	ice	ice	NOUN
dpc-2653	482	26	gel	gel	NOUN
dpc-2653	482	27	pack	pack	NOUN
dpc-2653	482	28	as	as	ADP
dpc-2653	482	29	less	less	ADV
dpc-2653	482	30	expensive	expensive	ADJ
dpc-2653	482	31	alternative	alternative	NOUN
dpc-2653	482	32	for	for	ADP
dpc-2653	482	33	prevention	prevention	NOUN
dpc-2653	482	34	of	of	ADP
dpc-2653	482	35	skin	skin	NOUN
dpc-2653	482	36	and	and	CCONJ
dpc-2653	482	37	nail	nail	NOUN
dpc-2653	482	38	toxicity	toxicity	NOUN
dpc-2653	482	39	in	in	ADP
dpc-2653	482	40	patients	patient	NOUN
dpc-2653	482	41	with	with	ADP
dpc-2653	482	42	breast	breast	NOUN
dpc-2653	482	43	cancer	cancer	NOUN
dpc-2653	482	44	receiving	receive	VERB
dpc-2653	482	45	docetaxel	docetaxel	NOUN
dpc-2653	482	46	.	.	PUNCT
dpc-2653	483	1	2009;1114–1114	2009;1114–1114	X
dpc-2653	483	2	.	.	NOUN
dpc-2653	483	3	28	28	NUM
dpc-2653	483	4	.	.	PUNCT
dpc-2653	484	1	can	can	AUX
dpc-2653	484	2	g	g	NOUN
dpc-2653	484	3	,	,	PUNCT
dpc-2653	484	4	aydiner	aydiner	NOUN
dpc-2653	484	5	a	a	DET
dpc-2653	484	6	,	,	PUNCT
dpc-2653	484	7	cavdar	cavdar	NOUN
dpc-2653	484	8	i.	i.	NOUN
dpc-2653	484	9	taxane	taxane	NOUN
dpc-2653	484	10	-	-	PUNCT
dpc-2653	484	11	induced	induce	VERB
dpc-2653	484	12	nail	nail	NOUN
dpc-2653	484	13	changes	change	NOUN
dpc-2653	484	14	:	:	PUNCT
dpc-2653	484	15	predictors	predictor	NOUN
dpc-2653	484	16	and	and	CCONJ
dpc-2653	484	17	efficacy	efficacy	NOUN
dpc-2653	484	18	of	of	ADP
dpc-2653	484	19	the	the	DET
dpc-2653	484	20	use	use	NOUN
dpc-2653	484	21	of	of	ADP
dpc-2653	484	22	frozen	frozen	ADJ
dpc-2653	484	23	gloves	glove	NOUN
dpc-2653	484	24	and	and	CCONJ
dpc-2653	484	25	socks	sock	NOUN
dpc-2653	484	26	in	in	ADP
dpc-2653	484	27	the	the	DET
dpc-2653	484	28	prevention	prevention	NOUN
dpc-2653	484	29	of	of	ADP
dpc-2653	484	30	nail	nail	NOUN
dpc-2653	484	31	toxicity	toxicity	NOUN
dpc-2653	484	32	.	.	PUNCT
dpc-2653	485	1	eur	eur	PROPN
dpc-2653	485	2	j	j	PROPN
dpc-2653	485	3	oncol	oncol	PROPN
dpc-2653	485	4	nurs	nur	VERB
dpc-2653	485	5	[	[	X
dpc-2653	485	6	internet	internet	NOUN
dpc-2653	485	7	]	]	PUNCT
dpc-2653	485	8	.	.	PUNCT
dpc-2653	486	1	2012;16(3):270–5	2012;16(3):270–5	NUM
dpc-2653	486	2	.	.	PUNCT
dpc-2653	486	3	available	available	ADJ
dpc-2653	486	4	from	from	ADP
dpc-2653	486	5	:	:	PUNCT
dpc-2653	486	6	http://dx.doi.org/10.1016/j	http://dx.doi.org/10.1016/j	PROPN
dpc-2653	486	7	.	.	PROPN
dpc-2653	486	8	ejon.2011.06.007	ejon.2011.06.007	PROPN
dpc-2653	487	1	29	29	NUM
dpc-2653	487	2	.	.	PUNCT
dpc-2653	488	1	winther	winther	PROPN
dpc-2653	488	2	d	d	PROPN
dpc-2653	488	3	,	,	PUNCT
dpc-2653	488	4	saunte	saunte	PROPN
dpc-2653	488	5	dm	dm	PROPN
dpc-2653	488	6	,	,	PUNCT
dpc-2653	488	7	knap	knap	PROPN
dpc-2653	488	8	m	m	PROPN
dpc-2653	488	9	,	,	PUNCT
dpc-2653	488	10	haahr	haahr	ADJ
dpc-2653	488	11	v	v	PROPN
dpc-2653	488	12	,	,	PUNCT
dpc-2653	488	13	jensen	jensen	PROPN
dpc-2653	488	14	ab	ab	PROPN
dpc-2653	488	15	.	.	PUNCT
dpc-2653	489	1	nail	nail	NOUN
dpc-2653	489	2	changes	change	NOUN
dpc-2653	489	3	due	due	ADJ
dpc-2653	489	4	to	to	ADP
dpc-2653	489	5	docetaxel	docetaxel	NOUN
dpc-2653	489	6	a	a	DET
dpc-2653	489	7	neglected	neglect	VERB
dpc-2653	489	8	side	side	NOUN
dpc-2653	489	9	effect	effect	NOUN
dpc-2653	489	10	and	and	CCONJ
dpc-2653	489	11	nuisance	nuisance	NOUN
dpc-2653	489	12	for	for	ADP
dpc-2653	489	13	the	the	DET
dpc-2653	489	14	patient	patient	NOUN
dpc-2653	489	15	.	.	PUNCT
dpc-2653	490	1	support	support	NOUN
dpc-2653	490	2	care	care	NOUN
dpc-2653	490	3	cancer	cancer	NOUN
dpc-2653	490	4	.	.	PUNCT
dpc-2653	491	1	2007;15(10):1191–7	2007;15(10):1191–7	X
dpc-2653	491	2	.	.	NOUN
dpc-2653	491	3	30	30	NUM
dpc-2653	491	4	.	.	PUNCT
dpc-2653	491	5	cecco	cecco	PROPN
dpc-2653	491	6	s	s	PROPN
dpc-2653	491	7	,	,	PUNCT
dpc-2653	491	8	aliberti	aliberti	PROPN
dpc-2653	491	9	m	m	PROPN
dpc-2653	491	10	,	,	PUNCT
dpc-2653	491	11	baldo	baldo	PROPN
dpc-2653	491	12	p	p	X
dpc-2653	491	13	,	,	PUNCT
dpc-2653	491	14	giacomin	giacomin	ADJ
dpc-2653	491	15	e	e	NOUN
dpc-2653	491	16	,	,	PUNCT
dpc-2653	491	17	leone	leone	PROPN
dpc-2653	491	18	r.	r.	PROPN
dpc-2653	491	19	safety	safety	PROPN
dpc-2653	491	20	and	and	CCONJ
dpc-2653	491	21	efficacy	efficacy	NOUN
dpc-2653	491	22	evaluation	evaluation	NOUN
dpc-2653	491	23	of	of	ADP
dpc-2653	491	24	albumin	albumin	NOUN
dpc-2653	491	25	-	-	PUNCT
dpc-2653	491	26	bound	bind	VERB
dpc-2653	491	27	paclitaxel	paclitaxel	NOUN
dpc-2653	491	28	.	.	PUNCT
dpc-2653	492	1	expert	expert	NOUN
dpc-2653	492	2	opin	opin	NOUN
dpc-2653	492	3	drug	drug	NOUN
dpc-2653	492	4	saf	saf	PROPN
dpc-2653	492	5	.	.	PUNCT
dpc-2653	493	1	2014;13(4):511–20	2014;13(4):511–20	NUM
dpc-2653	493	2	.	.	PUNCT
dpc-2653	494	1	31	31	NUM
dpc-2653	494	2	.	.	PUNCT
dpc-2653	495	1	socinski	socinski	PROPN
dpc-2653	495	2	ma	ma	PROPN
dpc-2653	495	3	,	,	PUNCT
dpc-2653	495	4	bondarenko	bondarenko	PROPN
dpc-2653	495	5	i	i	PROPN
dpc-2653	495	6	,	,	PUNCT
dpc-2653	495	7	karaseva	karaseva	PROPN
dpc-2653	495	8	na	na	PROPN
dpc-2653	495	9	,	,	PUNCT
dpc-2653	495	10	makhson	makhson	PROPN
dpc-2653	495	11	am	am	PROPN
dpc-2653	495	12	,	,	PUNCT
dpc-2653	495	13	vynnychenko	vynnychenko	PROPN
dpc-2653	495	14	i	i	PROPN
dpc-2653	495	15	,	,	PUNCT
dpc-2653	495	16	okamoto	okamoto	PROPN
dpc-2653	496	1	i	i	PROPN
dpc-2653	496	2	,	,	PUNCT
dpc-2653	496	3	et	et	PROPN
dpc-2653	496	4	al	al	PROPN
dpc-2653	496	5	.	.	PROPN
dpc-2653	496	6	weekly	weekly	PROPN
dpc-2653	496	7	nab	nab	NOUN
dpc-2653	496	8	-	-	PUNCT
dpc-2653	496	9	paclitaxel	paclitaxel	ADJ
dpc-2653	496	10	in	in	ADP
dpc-2653	496	11	combination	combination	NOUN
dpc-2653	496	12	with	with	ADP
dpc-2653	496	13	carboplatin	carboplatin	NOUN
dpc-2653	496	14	versus	versus	ADP
dpc-2653	496	15	solvent	solvent	NOUN
dpc-2653	496	16	-	-	PUNCT
dpc-2653	496	17	based	base	VERB
dpc-2653	496	18	paclitaxel	paclitaxel	PROPN
dpc-2653	496	19	plus	plus	CCONJ
dpc-2653	496	20	carboplatin	carboplatin	NOUN
dpc-2653	496	21	as	as	ADP
dpc-2653	496	22	first	first	ADJ
dpc-2653	496	23	-	-	PUNCT
dpc-2653	496	24	line	line	NOUN
dpc-2653	496	25	therapy	therapy	NOUN
dpc-2653	496	26	in	in	ADP
dpc-2653	496	27	patients	patient	NOUN
dpc-2653	496	28	with	with	ADP
dpc-2653	496	29	advanced	advanced	ADJ
dpc-2653	496	30	non	non	ADJ
dpc-2653	496	31	-	-	ADJ
dpc-2653	496	32	small	small	ADJ
dpc-2653	496	33	-	-	PUNCT
dpc-2653	496	34	cell	cell	NOUN
dpc-2653	496	35	lung	lung	NOUN
dpc-2653	496	36	cancer	cancer	NOUN
dpc-2653	496	37	:	:	PUNCT
dpc-2653	496	38	final	final	ADJ
dpc-2653	496	39	results	result	NOUN
dpc-2653	496	40	of	of	ADP
dpc-2653	496	41	a	a	DET
dpc-2653	496	42	phase	phase	NOUN
dpc-2653	496	43	iii	iii	NOUN
dpc-2653	496	44	trial	trial	NOUN
dpc-2653	496	45	.	.	PUNCT
dpc-2653	497	1	j	j	PROPN
dpc-2653	497	2	clin	clin	PROPN
dpc-2653	497	3	oncol	oncol	PROPN
dpc-2653	497	4	.	.	PUNCT
dpc-2653	498	1	2012;30(17):2055–62	2012;30(17):2055–62	NUM
dpc-2653	498	2	.	.	PUNCT
dpc-2653	499	1	at	at	ADP
dpc-2653	499	2	present	present	ADJ
dpc-2653	499	3	,	,	PUNCT
dpc-2653	499	4	there	there	PRON
dpc-2653	499	5	is	be	VERB
dpc-2653	499	6	a	a	DET
dpc-2653	499	7	paucity	paucity	NOUN
dpc-2653	499	8	of	of	ADP
dpc-2653	499	9	data	datum	NOUN
dpc-2653	499	10	regarding	regard	VERB
dpc-2653	499	11	nail	nail	NOUN
dpc-2653	499	12	involvement	involvement	NOUN
dpc-2653	499	13	and	and	CCONJ
dpc-2653	499	14	its	its	PRON
dpc-2653	499	15	impact	impact	NOUN
dpc-2653	499	16	on	on	ADP
dpc-2653	499	17	the	the	DET
dpc-2653	499	18	functional	functional	ADJ
dpc-2653	499	19	and	and	CCONJ
dpc-2653	499	20	emotional	emotional	ADJ
dpc-2653	499	21	status	status	NOUN
dpc-2653	499	22	of	of	ADP
dpc-2653	499	23	the	the	DET
dpc-2653	499	24	patient	patient	NOUN
dpc-2653	499	25	,	,	PUNCT
dpc-2653	499	26	during	during	ADP
dpc-2653	499	27	the	the	DET
dpc-2653	499	28	course	course	NOUN
dpc-2653	499	29	of	of	ADP
dpc-2653	499	30	the	the	DET
dpc-2653	499	31	diverse	diverse	ADJ
dpc-2653	499	32	oncologic	oncologic	NOUN
dpc-2653	499	33	treatments	treatment	NOUN
dpc-2653	499	34	.	.	PUNCT
dpc-2653	500	1	the	the	DET
dpc-2653	500	2	frequency	frequency	NOUN
dpc-2653	500	3	of	of	ADP
dpc-2653	500	4	nail	nail	NOUN
dpc-2653	500	5	involvement	involvement	NOUN
dpc-2653	500	6	,	,	PUNCT
dpc-2653	500	7	especially	especially	ADV
dpc-2653	500	8	with	with	ADP
dpc-2653	500	9	immunotherapy	immunotherapy	NOUN
dpc-2653	500	10	and	and	CCONJ
dpc-2653	500	11	new	new	ADJ
dpc-2653	500	12	targeted	target	VERB
dpc-2653	500	13	agents	agent	NOUN
dpc-2653	500	14	remains	remain	VERB
dpc-2653	500	15	 	 	SPACE
dpc-2653	500	16	unknown	unknown	ADJ
dpc-2653	500	17	.	.	PUNCT
dpc-2653	501	1	based	base	VERB
dpc-2653	501	2	on	on	ADP
dpc-2653	501	3	the	the	DET
dpc-2653	501	4	literature	literature	NOUN
dpc-2653	501	5	,	,	PUNCT
dpc-2653	501	6	it	it	PRON
dpc-2653	501	7	has	have	AUX
dpc-2653	501	8	been	be	AUX
dpc-2653	501	9	observed	observe	VERB
dpc-2653	501	10	that	that	SCONJ
dpc-2653	501	11	patients	patient	NOUN
dpc-2653	501	12	with	with	ADP
dpc-2653	501	13	different	different	ADJ
dpc-2653	501	14	cancer	cancer	NOUN
dpc-2653	501	15	types	type	NOUN
dpc-2653	501	16	receiving	receive	VERB
dpc-2653	501	17	different	different	ADJ
dpc-2653	501	18	regimens	regimen	NOUN
dpc-2653	501	19	may	may	AUX
dpc-2653	501	20	develop	develop	VERB
dpc-2653	501	21	the	the	DET
dpc-2653	501	22	same	same	ADJ
dpc-2653	501	23	nail	nail	NOUN
dpc-2653	501	24	disorder	disorder	NOUN
dpc-2653	501	25	,	,	PUNCT
dpc-2653	501	26	whereas	whereas	SCONJ
dpc-2653	501	27	patients	patient	NOUN
dpc-2653	501	28	with	with	ADP
dpc-2653	501	29	the	the	DET
dpc-2653	501	30	same	same	ADJ
dpc-2653	501	31	type	type	NOUN
dpc-2653	501	32	of	of	ADP
dpc-2653	501	33	cancer	cancer	NOUN
dpc-2653	501	34	under	under	ADP
dpc-2653	501	35	the	the	DET
dpc-2653	501	36	same	same	ADJ
dpc-2653	501	37	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	501	38	treatment	treatment	NOUN
dpc-2653	501	39	may	may	AUX
dpc-2653	501	40	develop	develop	VERB
dpc-2653	501	41	different	different	ADJ
dpc-2653	501	42	types	type	NOUN
dpc-2653	501	43	of	of	ADP
dpc-2653	501	44	nail	nail	NOUN
dpc-2653	501	45	alterations	alteration	NOUN
dpc-2653	501	46	.	.	PUNCT
dpc-2653	502	1	the	the	DET
dpc-2653	502	2	underlying	underlie	VERB
dpc-2653	502	3	mechanisms	mechanism	NOUN
dpc-2653	502	4	of	of	ADP
dpc-2653	502	5	the	the	DET
dpc-2653	502	6	varying	vary	VERB
dpc-2653	502	7	individual	individual	ADJ
dpc-2653	502	8	susceptibility	susceptibility	NOUN
dpc-2653	502	9	and	and	CCONJ
dpc-2653	502	10	the	the	DET
dpc-2653	502	11	diverse	diverse	ADJ
dpc-2653	502	12	nail	nail	NOUN
dpc-2653	502	13	responses	response	NOUN
dpc-2653	502	14	to	to	ADP
dpc-2653	502	15	various	various	ADJ
dpc-2653	502	16	anticancer	anticancer	NOUN
dpc-2653	502	17	treatments	treatment	NOUN
dpc-2653	502	18	need	need	VERB
dpc-2653	502	19	further	further	ADJ
dpc-2653	502	20	investigation	investigation	NOUN
dpc-2653	502	21	.	.	PUNCT
dpc-2653	503	1	it	it	PRON
dpc-2653	503	2	is	be	AUX
dpc-2653	503	3	critical	critical	ADJ
dpc-2653	503	4	to	to	PART
dpc-2653	503	5	improve	improve	VERB
dpc-2653	503	6	our	our	PRON
dpc-2653	503	7	understanding	understanding	NOUN
dpc-2653	503	8	of	of	ADP
dpc-2653	503	9	the	the	DET
dpc-2653	503	10	underlying	underlie	VERB
dpc-2653	503	11	pathogenesis	pathogenesis	NOUN
dpc-2653	503	12	of	of	ADP
dpc-2653	503	13	nail	nail	NOUN
dpc-2653	503	14	toxicity	toxicity	NOUN
dpc-2653	503	15	and	and	CCONJ
dpc-2653	503	16	potential	potential	ADJ
dpc-2653	503	17	risk	risk	NOUN
dpc-2653	503	18	factors	factor	NOUN
dpc-2653	503	19	in	in	ADP
dpc-2653	503	20	order	order	NOUN
dpc-2653	503	21	to	to	PART
dpc-2653	503	22	develop	develop	VERB
dpc-2653	503	23	effective	effective	ADJ
dpc-2653	503	24	evidence	evidence	NOUN
dpc-2653	503	25	-	-	PUNCT
dpc-2653	503	26	based	base	VERB
dpc-2653	503	27	management	management	NOUN
dpc-2653	503	28	strategies	strategy	NOUN
dpc-2653	503	29	,	,	PUNCT
dpc-2653	503	30	maintain	maintain	VERB
dpc-2653	503	31	patients	patient	NOUN
dpc-2653	503	32	’	'	PUNCT
dpc-2653	503	33	health	health	NOUN
dpc-2653	503	34	-	-	PUNCT
dpc-2653	503	35	related	relate	VERB
dpc-2653	503	36	quality	quality	NOUN
dpc-2653	503	37	of	of	ADP
dpc-2653	503	38	life	life	NOUN
dpc-2653	503	39	and	and	CCONJ
dpc-2653	503	40	ensure	ensure	VERB
dpc-2653	503	41	optimal	optimal	ADJ
dpc-2653	503	42	dosing	dosing	NOUN
dpc-2653	503	43	of	of	ADP
dpc-2653	503	44	potentially	potentially	ADV
dpc-2653	503	45	life	life	NOUN
dpc-2653	503	46	-	-	PUNCT
dpc-2653	503	47	prolonging	prolong	VERB
dpc-2653	503	48	anticancer	anticancer	NOUN
dpc-2653	503	49	therapy	therapy	NOUN
dpc-2653	503	50	.	.	PUNCT
dpc-2653	504	1	references	reference	NOUN
dpc-2653	504	2	1	1	NUM
dpc-2653	504	3	.	.	PUNCT
dpc-2653	504	4	pavey	pavey	NOUN
dpc-2653	504	5	r	r	NOUN
dpc-2653	504	6	,	,	PUNCT
dpc-2653	504	7	kambil	kambil	PROPN
dpc-2653	504	8	s	s	PROPN
dpc-2653	504	9	,	,	PUNCT
dpc-2653	504	10	bhat	bhat	PROPN
dpc-2653	504	11	r.	r.	PROPN
dpc-2653	504	12	dermatological	dermatological	ADJ
dpc-2653	504	13	adverse	adverse	ADJ
dpc-2653	504	14	reactions	reaction	NOUN
dpc-2653	504	15	to	to	ADP
dpc-2653	504	16	cancer	cancer	NOUN
dpc-2653	504	17	chemotherapy	chemotherapy	NOUN
dpc-2653	504	18	.	.	PUNCT
dpc-2653	505	1	indian	indian	PROPN
dpc-2653	505	2	j	j	PROPN
dpc-2653	505	3	dermatol	dermatol	PROPN
dpc-2653	505	4	venereol	venereol	ADJ
dpc-2653	505	5	leprol	leprol	NOUN
dpc-2653	505	6	.	.	PUNCT
dpc-2653	506	1	2015;81(4):434	2015;81(4):434	NUM
dpc-2653	506	2	.	.	PUNCT
dpc-2653	507	1	2	2	X
dpc-2653	507	2	.	.	X
dpc-2653	507	3	piraccini	piraccini	PROPN
dpc-2653	507	4	bm	bm	PROPN
dpc-2653	507	5	,	,	PUNCT
dpc-2653	507	6	tosti	tosti	PROPN
dpc-2653	507	7	a.	a.	NOUN
dpc-2653	507	8	drug	drug	NOUN
dpc-2653	507	9	-	-	PUNCT
dpc-2653	507	10	induced	induce	VERB
dpc-2653	507	11	nail	nail	NOUN
dpc-2653	507	12	disorders	disorder	NOUN
dpc-2653	507	13	.	.	PUNCT
dpc-2653	508	1	incidence	incidence	NOUN
dpc-2653	508	2	,	,	PUNCT
dpc-2653	508	3	management	management	NOUN
dpc-2653	508	4	and	and	CCONJ
dpc-2653	508	5	prognosis	prognosis	NOUN
dpc-2653	508	6	.	.	PUNCT
dpc-2653	509	1	drug	drug	PROPN
dpc-2653	509	2	saf	saf	PROPN
dpc-2653	509	3	.	.	PROPN
dpc-2653	510	1	1999;21(3):187–201	1999;21(3):187–201	NUM
dpc-2653	510	2	.	.	NOUN
dpc-2653	510	3	3	3	NUM
dpc-2653	510	4	.	.	PUNCT
dpc-2653	510	5	hinds	hinds	PROPN
dpc-2653	510	6	g	g	PROPN
dpc-2653	510	7	,	,	PUNCT
dpc-2653	510	8	thomas	thomas	PROPN
dpc-2653	510	9	vd	vd	PROPN
dpc-2653	510	10	.	.	PUNCT
dpc-2653	511	1	malignancy	malignancy	NOUN
dpc-2653	511	2	and	and	CCONJ
dpc-2653	511	3	cancer	cancer	NOUN
dpc-2653	511	4	treatment	treatment	NOUN
dpc-2653	511	5	-	-	PUNCT
dpc-2653	511	6	related	relate	VERB
dpc-2653	511	7	hair	hair	NOUN
dpc-2653	511	8	and	and	CCONJ
dpc-2653	511	9	nail	nail	NOUN
dpc-2653	511	10	changes	change	NOUN
dpc-2653	511	11	.	.	PUNCT
dpc-2653	512	1	dermatol	dermatol	NOUN
dpc-2653	512	2	clin	clin	PROPN
dpc-2653	512	3	.	.	PUNCT
dpc-2653	513	1	2008;26(1):59–68	2008;26(1):59–68	X
dpc-2653	513	2	.	.	NOUN
dpc-2653	513	3	4	4	NUM
dpc-2653	513	4	.	.	NUM
dpc-2653	513	5	saraswat	saraswat	PROPN
dpc-2653	513	6	n	n	CCONJ
dpc-2653	513	7	,	,	PUNCT
dpc-2653	513	8	sood	sood	PROPN
dpc-2653	513	9	a	a	PRON
dpc-2653	513	10	,	,	PUNCT
dpc-2653	513	11	verma	verma	PROPN
dpc-2653	513	12	r	r	PROPN
dpc-2653	513	13	,	,	PUNCT
dpc-2653	513	14	kumar	kumar	PROPN
dpc-2653	513	15	d	d	PROPN
dpc-2653	513	16	,	,	PUNCT
dpc-2653	514	1	kumar	kumar	PROPN
dpc-2653	514	2	s.	s.	PROPN
dpc-2653	514	3	nail	nail	PROPN
dpc-2653	514	4	changes	change	NOUN
dpc-2653	514	5	induced	induce	VERB
dpc-2653	514	6	by	by	ADP
dpc-2653	514	7	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	514	8	agents	agent	NOUN
dpc-2653	514	9	.	.	PUNCT
dpc-2653	515	1	indian	indian	PROPN
dpc-2653	515	2	j	j	PROPN
dpc-2653	515	3	dermatol	dermatol	NOUN
dpc-2653	516	1	[	[	X
dpc-2653	516	2	internet	internet	NOUN
dpc-2653	516	3	]	]	PUNCT
dpc-2653	516	4	.	.	PUNCT
dpc-2653	517	1	2020	2020	NUM
dpc-2653	517	2	may	may	AUX
dpc-2653	517	3	1	1	NUM
dpc-2653	517	4	[	[	X
dpc-2653	517	5	cited	cite	VERB
dpc-2653	517	6	2021	2021	NUM
dpc-2653	517	7	apr	apr	NOUN
dpc-2653	517	8	18];65(3):193	18];65(3):193	NUM
dpc-2653	517	9	.	.	PUNCT
dpc-2653	518	1	available	available	ADJ
dpc-2653	518	2	from	from	ADP
dpc-2653	518	3	:	:	PUNCT
dpc-2653	518	4	http://www.e-ijd.org/text.asp?2020/65/3/193/282451	http://www.e-ijd.org/text.asp?2020/65/3/193/282451	PROPN
dpc-2653	518	5	5	5	NUM
dpc-2653	518	6	.	.	PUNCT
dpc-2653	519	1	daniel	daniel	PROPN
dpc-2653	519	2	cr	cr	PROPN
dpc-2653	519	3	,	,	PUNCT
dpc-2653	519	4	scher	scher	PROPN
dpc-2653	519	5	rk	rk	PROPN
dpc-2653	519	6	.	.	PUNCT
dpc-2653	520	1	nail	nail	NOUN
dpc-2653	520	2	changes	change	NOUN
dpc-2653	520	3	secondary	secondary	ADJ
dpc-2653	520	4	to	to	ADP
dpc-2653	520	5	systemic	systemic	ADJ
dpc-2653	520	6	drugs	drug	NOUN
dpc-2653	520	7	or	or	CCONJ
dpc-2653	520	8	ingestants	ingestant	NOUN
dpc-2653	520	9	.	.	PUNCT
dpc-2653	521	1	j	j	PROPN
dpc-2653	521	2	am	be	AUX
dpc-2653	521	3	acad	acad	ADJ
dpc-2653	521	4	dermatol	dermatol	NOUN
dpc-2653	521	5	.	.	PUNCT
dpc-2653	522	1	1984;10(2):250–8	1984;10(2):250–8	NUM
dpc-2653	522	2	.	.	PROPN
dpc-2653	523	1	6	6	NUM
dpc-2653	523	2	.	.	X
dpc-2653	523	3	chen	chen	PROPN
dpc-2653	523	4	w	w	PROPN
dpc-2653	523	5	,	,	PUNCT
dpc-2653	523	6	yu	yu	PROPN
dpc-2653	523	7	ys	ys	PROPN
dpc-2653	523	8	,	,	PUNCT
dpc-2653	523	9	liu	liu	PROPN
dpc-2653	523	10	yh	yh	PROPN
dpc-2653	523	11	,	,	PUNCT
dpc-2653	523	12	sheen	sheen	PROPN
dpc-2653	523	13	jm	jm	PROPN
dpc-2653	523	14	,	,	PUNCT
dpc-2653	523	15	hsiao	hsiao	PROPN
dpc-2653	523	16	cc	cc	PROPN
dpc-2653	523	17	.	.	PROPN
dpc-2653	523	18	nail	nail	NOUN
dpc-2653	523	19	changes	change	NOUN
dpc-2653	523	20	associated	associate	VERB
dpc-2653	523	21	with	with	ADP
dpc-2653	523	22	chemotherapy	chemotherapy	NOUN
dpc-2653	523	23	in	in	ADP
dpc-2653	523	24	children	child	NOUN
dpc-2653	523	25	.	.	PUNCT
dpc-2653	524	1	j	j	PROPN
dpc-2653	524	2	eur	eur	PROPN
dpc-2653	524	3	acad	acad	PROPN
dpc-2653	524	4	dermatology	dermatology	NOUN
dpc-2653	524	5	venereol	venereol	NOUN
dpc-2653	524	6	.	.	PUNCT
dpc-2653	525	1	2007;21(2):186–90	2007;21(2):186–90	X
dpc-2653	525	2	.	.	X
dpc-2653	525	3	7	7	X
dpc-2653	525	4	.	.	X
dpc-2653	525	5	piraccini	piraccini	PROPN
dpc-2653	525	6	bm	bm	PROPN
dpc-2653	525	7	,	,	PUNCT
dpc-2653	525	8	iorizzo	iorizzo	VERB
dpc-2653	525	9	m	m	PROPN
dpc-2653	525	10	,	,	PUNCT
dpc-2653	525	11	starace	starace	PROPN
dpc-2653	525	12	m	m	PROPN
dpc-2653	525	13	,	,	PUNCT
dpc-2653	525	14	tosti	tosti	PROPN
dpc-2653	525	15	a.	a.	NOUN
dpc-2653	525	16	drug	drug	NOUN
dpc-2653	525	17	-	-	PUNCT
dpc-2653	525	18	induced	induce	VERB
dpc-2653	525	19	nail	nail	NOUN
dpc-2653	525	20	diseases	disease	NOUN
dpc-2653	525	21	.	.	PUNCT
dpc-2653	526	1	dermatol	dermatol	NOUN
dpc-2653	526	2	clin	clin	PROPN
dpc-2653	526	3	.	.	PUNCT
dpc-2653	527	1	2006;24(3):387–91	2006;24(3):387–91	NUM
dpc-2653	527	2	.	.	NOUN
dpc-2653	527	3	8	8	NUM
dpc-2653	527	4	.	.	PUNCT
dpc-2653	527	5	piraccini	piraccini	PROPN
dpc-2653	527	6	bm	bm	PROPN
dpc-2653	527	7	,	,	PUNCT
dpc-2653	527	8	iorizzo	iorizzo	VERB
dpc-2653	527	9	m.	m.	NOUN
dpc-2653	527	10	drug	drug	NOUN
dpc-2653	527	11	reactions	reaction	NOUN
dpc-2653	527	12	affecting	affect	VERB
dpc-2653	527	13	the	the	DET
dpc-2653	527	14	nail	nail	NOUN
dpc-2653	527	15	unit	unit	NOUN
dpc-2653	527	16	:	:	PUNCT
dpc-2653	527	17	diagnosis	diagnosis	NOUN
dpc-2653	527	18	and	and	CCONJ
dpc-2653	527	19	management	management	NOUN
dpc-2653	527	20	.	.	PUNCT
dpc-2653	528	1	dermatol	dermatol	NOUN
dpc-2653	528	2	clin	clin	PROPN
dpc-2653	528	3	.	.	PUNCT
dpc-2653	529	1	2007;25(2):215–21	2007;25(2):215–21	NUM
dpc-2653	529	2	.	.	NOUN
dpc-2653	529	3	9	9	NUM
dpc-2653	529	4	.	.	X
dpc-2653	529	5	piraccini	piraccini	PROPN
dpc-2653	529	6	bm	bm	PROPN
dpc-2653	529	7	,	,	PUNCT
dpc-2653	529	8	iorizzo	iorizzo	VERB
dpc-2653	529	9	m	m	PROPN
dpc-2653	529	10	,	,	PUNCT
dpc-2653	529	11	antonucci	antonucci	PROPN
dpc-2653	529	12	a	a	X
dpc-2653	529	13	,	,	PUNCT
dpc-2653	529	14	tosti	tosti	PROPN
dpc-2653	529	15	a.	a.	NOUN
dpc-2653	529	16	drug	drug	NOUN
dpc-2653	529	17	-	-	PUNCT
dpc-2653	529	18	induced	induce	VERB
dpc-2653	529	19	nail	nail	NOUN
dpc-2653	529	20	abnormalities	abnormality	NOUN
dpc-2653	529	21	.	.	PUNCT
dpc-2653	530	1	expert	expert	NOUN
dpc-2653	530	2	opin	opin	NOUN
dpc-2653	530	3	drug	drug	NOUN
dpc-2653	530	4	saf	saf	PROPN
dpc-2653	530	5	.	.	PROPN
dpc-2653	530	6	2004;3(1):57–65	2004;3(1):57–65	NUM
dpc-2653	530	7	.	.	PUNCT
dpc-2653	531	1	10	10	NUM
dpc-2653	531	2	.	.	PUNCT
dpc-2653	532	1	uyttendaele	uyttendaele	PROPN
dpc-2653	532	2	h	h	NOUN
dpc-2653	532	3	,	,	PUNCT
dpc-2653	532	4	geyer	geyer	PROPN
dpc-2653	532	5	a	a	PRON
dpc-2653	532	6	,	,	PUNCT
dpc-2653	532	7	scher	scher	PROPN
dpc-2653	532	8	rk	rk	NOUN
dpc-2653	532	9	.	.	PUNCT
dpc-2653	532	10	drugs	drug	NOUN
dpc-2653	532	11	and	and	CCONJ
dpc-2653	532	12	nails	nail	NOUN
dpc-2653	532	13	.	.	PUNCT
dpc-2653	533	1	j	j	PROPN
dpc-2653	533	2	eur	eur	PROPN
dpc-2653	533	3	acad	acad	PROPN
dpc-2653	533	4	dermatology	dermatology	NOUN
dpc-2653	533	5	venereol	venereol	NOUN
dpc-2653	533	6	.	.	PUNCT
dpc-2653	534	1	2004;18(2):124–5	2004;18(2):124–5	X
dpc-2653	534	2	.	.	PUNCT
dpc-2653	535	1	11	11	NUM
dpc-2653	535	2	.	.	PUNCT
dpc-2653	536	1	kirby	kirby	PROPN
dpc-2653	536	2	js	js	PROPN
dpc-2653	536	3	mc	mc	PROPN
dpc-2653	536	4	.	.	PUNCT
dpc-2653	537	1	chemotherapy	chemotherapy	NOUN
dpc-2653	537	2	principles	principle	NOUN
dpc-2653	537	3	an	an	DET
dpc-2653	537	4	in	in	ADP
dpc-2653	537	5	-	-	PUNCT
dpc-2653	537	6	depth	depth	NOUN
dpc-2653	537	7	discussion	discussion	NOUN
dpc-2653	537	8	of	of	ADP
dpc-2653	537	9	the	the	DET
dpc-2653	537	10	techniques	technique	NOUN
dpc-2653	537	11	and	and	CCONJ
dpc-2653	537	12	its	its	PRON
dpc-2653	537	13	role	role	NOUN
dpc-2653	537	14	in	in	ADP
dpc-2653	537	15	cancer	cancer	NOUN
dpc-2653	537	16	treatment	treatment	NOUN
dpc-2653	537	17	.	.	PUNCT
dpc-2653	538	1	intralesional	intralesional	ADJ
dpc-2653	538	2	chemother	chemother	PROPN
dpc-2653	538	3	nonmelanoma	nonmelanoma	PROPN
dpc-2653	538	4	ski	ski	PROPN
dpc-2653	538	5	cancer	cancer	PROPN
dpc-2653	538	6	a	a	DET
dpc-2653	538	7	pract	pract	PROPN
dpc-2653	538	8	rev	rev	PROPN
dpc-2653	538	9	.	.	PROPN
dpc-2653	538	10	2010	2010	NUM
dpc-2653	538	11	;	;	PUNCT
dpc-2653	539	1	12	12	NUM
dpc-2653	539	2	.	.	PUNCT
dpc-2653	540	1	reyes	reyes	PROPN
dpc-2653	540	2	-	-	PUNCT
dpc-2653	540	3	habito	habito	PROPN
dpc-2653	540	4	cm	cm	PROPN
dpc-2653	540	5	,	,	PUNCT
dpc-2653	540	6	roh	roh	PROPN
dpc-2653	540	7	ek	ek	PROPN
dpc-2653	540	8	.	.	PROPN
dpc-2653	540	9	cutaneous	cutaneous	ADJ
dpc-2653	540	10	reactions	reaction	NOUN
dpc-2653	540	11	to	to	ADP
dpc-2653	540	12	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	540	13	drugs	drug	NOUN
dpc-2653	540	14	and	and	CCONJ
dpc-2653	540	15	targeted	target	VERB
dpc-2653	540	16	therapies	therapy	NOUN
dpc-2653	540	17	for	for	ADP
dpc-2653	540	18	cancer	cancer	NOUN
dpc-2653	540	19	:	:	PUNCT
dpc-2653	540	20	part	part	NOUN
dpc-2653	540	21	i.	i.	PROPN
dpc-2653	540	22	conventional	conventional	ADJ
dpc-2653	540	23	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	540	24	drugs	drug	NOUN
dpc-2653	540	25	.	.	PUNCT
dpc-2653	541	1	j	j	PROPN
dpc-2653	541	2	am	be	AUX
dpc-2653	541	3	acad	acad	X
dpc-2653	541	4	dermatol	dermatol	NOUN
dpc-2653	542	1	[	[	X
dpc-2653	542	2	internet	internet	NOUN
dpc-2653	542	3	]	]	PUNCT
dpc-2653	542	4	.	.	PUNCT
dpc-2653	543	1	2014;71(2):203.e1	2014;71(2):203.e1	PROPN
dpc-2653	543	2	-	-	PUNCT
dpc-2653	543	3	203.e12	203.e12	PROPN
dpc-2653	543	4	.	.	PUNCT
dpc-2653	543	5	available	available	ADJ
dpc-2653	543	6	from	from	ADP
dpc-2653	543	7	:	:	PUNCT
dpc-2653	543	8	http://	http://	PROPN
dpc-2653	543	9	dx.doi.org/10.1016/j.jaad.2014.04.014	dx.doi.org/10.1016/j.jaad.2014.04.014	NOUN
dpc-2653	543	10	13	13	NUM
dpc-2653	543	11	.	.	PUNCT
dpc-2653	544	1	heidary	heidary	PROPN
dpc-2653	544	2	n	n	CCONJ
dpc-2653	544	3	,	,	PUNCT
dpc-2653	544	4	naik	naik	PROPN
dpc-2653	544	5	h	h	PROPN
dpc-2653	544	6	,	,	PUNCT
dpc-2653	544	7	burgin	burgin	PROPN
dpc-2653	544	8	s.	s.	PROPN
dpc-2653	544	9	chemotherapeutic	chemotherapeutic	PROPN
dpc-2653	544	10	agents	agent	NOUN
dpc-2653	544	11	and	and	CCONJ
dpc-2653	544	12	the	the	DET
dpc-2653	544	13	skin	skin	NOUN
dpc-2653	544	14	:	:	PUNCT
dpc-2653	544	15	an	an	DET
dpc-2653	544	16	update	update	NOUN
dpc-2653	544	17	.	.	PUNCT
dpc-2653	545	1	j	j	PROPN
dpc-2653	545	2	am	be	AUX
dpc-2653	545	3	acad	acad	ADJ
dpc-2653	545	4	dermatol	dermatol	NOUN
dpc-2653	545	5	.	.	PUNCT
dpc-2653	546	1	2008;58(4):545–70	2008;58(4):545–70	NUM
dpc-2653	546	2	.	.	PUNCT
dpc-2653	547	1	review	review	VERB
dpc-2653	547	2	|	|	ADV
dpc-2653	547	3	dermatol	dermatol	ADJ
dpc-2653	547	4	pract	pract	NOUN
dpc-2653	547	5	concept	concept	NOUN
dpc-2653	547	6	.	.	PUNCT
dpc-2653	548	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	548	2	17	17	NUM
dpc-2653	548	3	48	48	NUM
dpc-2653	548	4	.	.	PUNCT
dpc-2653	549	1	robert	robert	PROPN
dpc-2653	549	2	c	c	PROPN
dpc-2653	549	3	,	,	PUNCT
dpc-2653	549	4	sibaud	sibaud	NOUN
dpc-2653	549	5	v	v	NOUN
dpc-2653	549	6	,	,	PUNCT
dpc-2653	549	7	mateus	mateus	PROPN
dpc-2653	549	8	c	c	PROPN
dpc-2653	549	9	,	,	PUNCT
dpc-2653	549	10	verschoore	verschoore	PROPN
dpc-2653	549	11	m	m	PROPN
dpc-2653	549	12	,	,	PUNCT
dpc-2653	549	13	charles	charles	PROPN
dpc-2653	549	14	c	c	PROPN
dpc-2653	549	15	,	,	PUNCT
dpc-2653	549	16	lanoy	lanoy	ADJ
dpc-2653	549	17	e	e	NOUN
dpc-2653	549	18	,	,	PUNCT
dpc-2653	549	19	et	et	PROPN
dpc-2653	549	20	al	al	PROPN
dpc-2653	549	21	.	.	PUNCT
dpc-2653	550	1	nail	nail	NOUN
dpc-2653	550	2	toxicities	toxicity	NOUN
dpc-2653	550	3	induced	induce	VERB
dpc-2653	550	4	by	by	ADP
dpc-2653	550	5	systemic	systemic	ADJ
dpc-2653	550	6	anticancer	anticancer	NOUN
dpc-2653	550	7	treatments	treatment	NOUN
dpc-2653	550	8	.	.	PUNCT
dpc-2653	551	1	lancet	lancet	PROPN
dpc-2653	551	2	oncol	oncol	PROPN
dpc-2653	552	1	[	[	X
dpc-2653	552	2	internet	internet	NOUN
dpc-2653	552	3	]	]	PUNCT
dpc-2653	552	4	.	.	PUNCT
dpc-2653	553	1	2015;16(4):e181–9	2015;16(4):e181–9	X
dpc-2653	553	2	.	.	PUNCT
dpc-2653	553	3	available	available	ADJ
dpc-2653	553	4	from	from	ADP
dpc-2653	553	5	:	:	PUNCT
dpc-2653	553	6	http://dx.doi.org/10.1016/s1470-2045(14)71133-7	http://dx.doi.org/10.1016/s1470-2045(14)71133-7	PROPN
dpc-2653	553	7	49	49	NUM
dpc-2653	553	8	.	.	PUNCT
dpc-2653	554	1	sibaud	sibaud	NOUN
dpc-2653	554	2	v	v	PROPN
dpc-2653	554	3	,	,	PUNCT
dpc-2653	554	4	fricain	fricain	PROPN
dpc-2653	554	5	jc	jc	PROPN
dpc-2653	554	6	,	,	PUNCT
dpc-2653	554	7	baran	baran	NOUN
dpc-2653	554	8	r	r	NOUN
dpc-2653	554	9	,	,	PUNCT
dpc-2653	554	10	robert	robert	PROPN
dpc-2653	554	11	c.	c.	PROPN
dpc-2653	554	12	pigmentary	pigmentary	PROPN
dpc-2653	554	13	disorders	disorder	NOUN
dpc-2653	554	14	induced	induce	VERB
dpc-2653	554	15	by	by	ADP
dpc-2653	554	16	anticancer	anticancer	NOUN
dpc-2653	554	17	agents	agent	NOUN
dpc-2653	554	18	.	.	PUNCT
dpc-2653	555	1	part	part	NOUN
dpc-2653	556	1	i	i	NOUN
dpc-2653	556	2	:	:	PUNCT
dpc-2653	556	3	chemotherapy	chemotherapy	NOUN
dpc-2653	556	4	.	.	PUNCT
dpc-2653	557	1	ann	ann	PROPN
dpc-2653	557	2	dermatol	dermatol	PROPN
dpc-2653	557	3	venereol	venereol	NOUN
dpc-2653	557	4	.	.	PUNCT
dpc-2653	558	1	2013;140(3):183–96	2013;140(3):183–96	X
dpc-2653	558	2	.	.	X
dpc-2653	559	1	50	50	NUM
dpc-2653	559	2	.	.	X
dpc-2653	559	3	harrison	harrison	PROPN
dpc-2653	559	4	bm	bm	PROPN
dpc-2653	559	5	,	,	PUNCT
dpc-2653	559	6	wood	wood	PROPN
dpc-2653	559	7	cbs	cbs	PROPN
dpc-2653	559	8	.	.	PUNCT
dpc-2653	560	1	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	560	2	and	and	CCONJ
dpc-2653	560	3	pigmentation	pigmentation	NOUN
dpc-2653	560	4	.	.	PUNCT
dpc-2653	561	1	br	br	PROPN
dpc-2653	561	2	med	med	PROPN
dpc-2653	561	3	j.	j.	PROPN
dpc-2653	561	4	1972;2(5809):352	1972;2(5809):352	PROPN
dpc-2653	561	5	.	.	PROPN
dpc-2653	561	6	51	51	NUM
dpc-2653	561	7	.	.	PUNCT
dpc-2653	562	1	shah	shah	PROPN
dpc-2653	562	2	pc	pc	PROPN
dpc-2653	562	3	,	,	PUNCT
dpc-2653	562	4	rao	rao	PROPN
dpc-2653	562	5	krp	krp	PROPN
dpc-2653	562	6	,	,	PUNCT
dpc-2653	562	7	patel	patel	PROPN
dpc-2653	562	8	ar	ar	PROPN
dpc-2653	562	9	.	.	PROPN
dpc-2653	562	10	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	562	11	induced	induce	VERB
dpc-2653	562	12	nail	nail	NOUN
dpc-2653	562	13	pigmentation	pigmentation	NOUN
dpc-2653	562	14	.	.	PUNCT
dpc-2653	563	1	br	br	PROPN
dpc-2653	563	2	j	j	PROPN
dpc-2653	563	3	dermatol	dermatol	NOUN
dpc-2653	563	4	.	.	PUNCT
dpc-2653	564	1	1978;98(6):675–80	1978;98(6):675–80	NUM
dpc-2653	564	2	.	.	PUNCT
dpc-2653	565	1	52	52	NUM
dpc-2653	565	2	.	.	PUNCT
dpc-2653	566	1	adam	adam	PROPN
dpc-2653	566	2	ba	ba	PROPN
dpc-2653	566	3	.	.	PUNCT
dpc-2653	567	1	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	567	2	nail	nail	NOUN
dpc-2653	567	3	pigmentation	pigmentation	NOUN
dpc-2653	567	4	.	.	PUNCT
dpc-2653	568	1	singapore	singapore	PROPN
dpc-2653	568	2	med	med	PROPN
dpc-2653	568	3	j.	j.	PROPN
dpc-2653	568	4	1981;22(1):35–7	1981;22(1):35–7	PROPN
dpc-2653	568	5	.	.	PUNCT
dpc-2653	569	1	53	53	NUM
dpc-2653	569	2	.	.	PUNCT
dpc-2653	570	1	prabodh	prabodh	PROPN
dpc-2653	570	2	s	s	PROPN
dpc-2653	570	3	,	,	PUNCT
dpc-2653	570	4	rao	rao	PROPN
dpc-2653	570	5	krp	krp	PROPN
dpc-2653	570	6	,	,	PUNCT
dpc-2653	570	7	ashok	ashok	NOUN
dpc-2653	570	8	p.	p.	PROPN
dpc-2653	570	9	cyclophosphamide	cyclophosphamide	PROPN
dpc-2653	570	10	-	-	PUNCT
dpc-2653	570	11	induced	induce	VERB
dpc-2653	570	12	nail	nail	NOUN
dpc-2653	570	13	pigmentation	pigmentation	NOUN
dpc-2653	570	14	.	.	PUNCT
dpc-2653	571	1	br	br	PROPN
dpc-2653	571	2	j	j	PROPN
dpc-2653	571	3	haematol	haematol	NOUN
dpc-2653	571	4	.	.	PUNCT
dpc-2653	572	1	2002;117(1):2	2002;117(1):2	NUM
dpc-2653	572	2	.	.	PROPN
dpc-2653	572	3	54	54	NUM
dpc-2653	572	4	.	.	PUNCT
dpc-2653	573	1	dave	dave	PROPN
dpc-2653	573	2	s	s	PROPN
dpc-2653	573	3	,	,	PUNCT
dpc-2653	573	4	thappa	thappa	PROPN
dpc-2653	573	5	dm	dm	PROPN
dpc-2653	573	6	.	.	PUNCT
dpc-2653	573	7	peculiar	peculiar	ADJ
dpc-2653	573	8	pattern	pattern	NOUN
dpc-2653	573	9	of	of	ADP
dpc-2653	573	10	nail	nail	NOUN
dpc-2653	573	11	pigmentation	pigmentation	NOUN
dpc-2653	573	12	following	follow	VERB
dpc-2653	573	13	cyclophosphamide	cyclophosphamide	NOUN
dpc-2653	573	14	therapy	therapy	NOUN
dpc-2653	573	15	.	.	PUNCT
dpc-2653	574	1	dermatol	dermatol	NOUN
dpc-2653	574	2	online	online	PROPN
dpc-2653	574	3	j.	j.	PROPN
dpc-2653	574	4	2003;9(3):148–51	2003;9(3):148–51	NUM
dpc-2653	574	5	.	.	PUNCT
dpc-2653	575	1	55	55	NUM
dpc-2653	575	2	.	.	PUNCT
dpc-2653	576	1	valero	valero	PROPN
dpc-2653	576	2	v	v	PROPN
dpc-2653	576	3	,	,	PUNCT
dpc-2653	576	4	holmes	holmes	PROPN
dpc-2653	576	5	fa	fa	PROPN
dpc-2653	576	6	,	,	PUNCT
dpc-2653	576	7	walters	walters	PROPN
dpc-2653	576	8	rs	rs	PROPN
dpc-2653	576	9	,	,	PUNCT
dpc-2653	576	10	theriault	theriault	VERB
dpc-2653	576	11	rl	rl	PROPN
dpc-2653	576	12	,	,	PUNCT
dpc-2653	576	13	esparza	esparza	PROPN
dpc-2653	576	14	l	l	PROPN
dpc-2653	576	15	,	,	PUNCT
dpc-2653	576	16	fraschini	fraschini	PROPN
dpc-2653	576	17	g	g	PROPN
dpc-2653	576	18	,	,	PUNCT
dpc-2653	576	19	et	et	PROPN
dpc-2653	576	20	al	al	PROPN
dpc-2653	576	21	.	.	PROPN
dpc-2653	576	22	phase	phase	PROPN
dpc-2653	576	23	ii	ii	NOUN
dpc-2653	576	24	trial	trial	NOUN
dpc-2653	576	25	of	of	ADP
dpc-2653	576	26	docetaxel	docetaxel	NOUN
dpc-2653	576	27	:	:	PUNCT
dpc-2653	576	28	a	a	DET
dpc-2653	576	29	new	new	ADJ
dpc-2653	576	30	,	,	PUNCT
dpc-2653	576	31	highly	highly	ADV
dpc-2653	576	32	effective	effective	ADJ
dpc-2653	576	33	antineoplastic	antineoplastic	ADJ
dpc-2653	576	34	agent	agent	NOUN
dpc-2653	576	35	in	in	ADP
dpc-2653	576	36	the	the	DET
dpc-2653	576	37	management	management	NOUN
dpc-2653	576	38	of	of	ADP
dpc-2653	576	39	patients	patient	NOUN
dpc-2653	576	40	with	with	ADP
dpc-2653	576	41	anthracycline	anthracycline	NOUN
dpc-2653	576	42	-	-	PUNCT
dpc-2653	576	43	resistant	resistant	ADJ
dpc-2653	576	44	metastatic	metastatic	ADJ
dpc-2653	576	45	breast	breast	NOUN
dpc-2653	576	46	cancer	cancer	NOUN
dpc-2653	576	47	.	.	PUNCT
dpc-2653	577	1	j	j	PROPN
dpc-2653	577	2	clin	clin	PROPN
dpc-2653	577	3	oncol	oncol	PROPN
dpc-2653	577	4	.	.	PUNCT
dpc-2653	578	1	1995;13(12):2886–94	1995;13(12):2886–94	NUM
dpc-2653	578	2	.	.	X
dpc-2653	579	1	56	56	NUM
dpc-2653	579	2	.	.	PUNCT
dpc-2653	579	3	du	du	PROPN
dpc-2653	579	4	a	a	X
dpc-2653	579	5	,	,	PUNCT
dpc-2653	579	6	vivier	vivier	PROPN
dpc-2653	579	7	d.	d.	PROPN
dpc-2653	579	8	british	british	PROPN
dpc-2653	579	9	journal	journal	PROPN
dpc-2653	579	10	of	of	ADP
dpc-2653	579	11	dermatology	dermatology	NOUN
dpc-2653	579	12	2002	2002	NUM
dpc-2653	579	13	;	;	PUNCT
dpc-2653	579	14	146	146	NUM
dpc-2653	579	15	:	:	SYM
dpc-2653	579	16	705	705	NUM
dpc-2653	579	17	–	–	PUNCT
dpc-2653	579	18	718	718	NUM
dpc-2653	579	19	.	.	PUNCT
dpc-2653	579	20	2002;705–18	2002;705–18	NUM
dpc-2653	579	21	.	.	PUNCT
dpc-2653	580	1	57	57	NUM
dpc-2653	580	2	.	.	PUNCT
dpc-2653	580	3	mourad	mourad	PROPN
dpc-2653	580	4	ya	ya	PROPN
dpc-2653	580	5	,	,	PUNCT
dpc-2653	580	6	matta	matta	PROPN
dpc-2653	580	7	-	-	PUNCT
dpc-2653	580	8	muallem	muallem	PROPN
dpc-2653	580	9	m	m	PROPN
dpc-2653	580	10	,	,	PUNCT
dpc-2653	580	11	shamseddine	shamseddine	ADJ
dpc-2653	580	12	a.	a.	NOUN
dpc-2653	580	13	nail	nail	NOUN
dpc-2653	580	14	toxicity	toxicity	NOUN
dpc-2653	580	15	related	relate	VERB
dpc-2653	580	16	to	to	ADP
dpc-2653	580	17	taxanes	taxane	NOUN
dpc-2653	580	18	.	.	PUNCT
dpc-2653	581	1	dermatol	dermatol	NOUN
dpc-2653	581	2	online	online	PROPN
dpc-2653	581	3	j.	j.	PROPN
dpc-2653	581	4	2003;9(3):152–4	2003;9(3):152–4	PROPN
dpc-2653	581	5	.	.	PROPN
dpc-2653	581	6	58	58	NUM
dpc-2653	581	7	.	.	PUNCT
dpc-2653	582	1	hardin	hardin	PROPN
dpc-2653	582	2	j	j	PROPN
dpc-2653	582	3	,	,	PUNCT
dpc-2653	582	4	haber	haber	PROPN
dpc-2653	582	5	rm	rm	PROPN
dpc-2653	582	6	.	.	PROPN
dpc-2653	582	7	onychomadesis	onychomadesis	PROPN
dpc-2653	582	8	:	:	PUNCT
dpc-2653	582	9	literature	literature	PROPN
dpc-2653	582	10	review	review	PROPN
dpc-2653	582	11	.	.	PUNCT
dpc-2653	583	1	br	br	PROPN
dpc-2653	583	2	j	j	PROPN
dpc-2653	583	3	dermatol	dermatol	NOUN
dpc-2653	583	4	.	.	PUNCT
dpc-2653	584	1	2015;172(3):592–6	2015;172(3):592–6	NUM
dpc-2653	584	2	.	.	PROPN
dpc-2653	585	1	59	59	NUM
dpc-2653	585	2	.	.	PUNCT
dpc-2653	586	1	hussain	hussain	PROPN
dpc-2653	586	2	s	s	PROPN
dpc-2653	586	3	,	,	PUNCT
dpc-2653	586	4	anderson	anderson	PROPN
dpc-2653	586	5	dn	dn	PROPN
dpc-2653	586	6	,	,	PUNCT
dpc-2653	586	7	salvatti	salvatti	VERB
dpc-2653	586	8	me	i	PRON
dpc-2653	586	9	,	,	PUNCT
dpc-2653	586	10	adamson	adamson	PROPN
dpc-2653	586	11	b	b	PROPN
dpc-2653	586	12	,	,	PUNCT
dpc-2653	586	13	mcmanus	mcmanus	PROPN
dpc-2653	586	14	m	m	PROPN
dpc-2653	586	15	,	,	PUNCT
dpc-2653	586	16	braverman	braverman	VERB
dpc-2653	586	17	as	as	ADP
dpc-2653	586	18	.	.	PUNCT
dpc-2653	586	19	onycholysis	onycholysis	NOUN
dpc-2653	586	20	as	as	ADP
dpc-2653	586	21	a	a	DET
dpc-2653	586	22	complication	complication	NOUN
dpc-2653	586	23	of	of	ADP
dpc-2653	586	24	systemic	systemic	ADJ
dpc-2653	586	25	chemotherapy	chemotherapy	NOUN
dpc-2653	586	26	.	.	PUNCT
dpc-2653	587	1	cancer	cancer	NOUN
dpc-2653	587	2	.	.	PUNCT
dpc-2653	588	1	2000;88(10):2367–71	2000;88(10):2367–71	NUM
dpc-2653	588	2	.	.	PUNCT
dpc-2653	589	1	60	60	NUM
dpc-2653	589	2	.	.	PUNCT
dpc-2653	589	3	maino	maino	PROPN
dpc-2653	589	4	kl	kl	PROPN
dpc-2653	589	5	,	,	PUNCT
dpc-2653	589	6	norwood	norwood	PROPN
dpc-2653	589	7	c	c	PROPN
dpc-2653	589	8	,	,	PUNCT
dpc-2653	589	9	stashower	stashower	VERB
dpc-2653	589	10	me	i	PRON
dpc-2653	589	11	.	.	PUNCT
dpc-2653	590	1	onycholysis	onycholysis	NOUN
dpc-2653	590	2	with	with	ADP
dpc-2653	590	3	the	the	DET
dpc-2653	590	4	appearance	appearance	NOUN
dpc-2653	590	5	of	of	ADP
dpc-2653	590	6	a	a	DET
dpc-2653	590	7	“	"	PUNCT
dpc-2653	590	8	sunset	sunset	NOUN
dpc-2653	590	9	”	"	PUNCT
dpc-2653	590	10	secondary	secondary	ADJ
dpc-2653	590	11	to	to	AUX
dpc-2653	590	12	capecitabine	capecitabine	VERB
dpc-2653	590	13	.	.	PUNCT
dpc-2653	591	1	cutis	cutis	NOUN
dpc-2653	591	2	.	.	PUNCT
dpc-2653	592	1	2003;72(3):234–6	2003;72(3):234–6	NUM
dpc-2653	592	2	.	.	PUNCT
dpc-2653	593	1	61	61	NUM
dpc-2653	593	2	.	.	PUNCT
dpc-2653	594	1	kochupillai	kochupillai	PROPN
dpc-2653	594	2	v	v	PROPN
dpc-2653	594	3	,	,	PUNCT
dpc-2653	594	4	prabhu	prabhu	PROPN
dpc-2653	594	5	m	m	PROPN
dpc-2653	594	6	,	,	PUNCT
dpc-2653	594	7	bhide	bhide	PROPN
dpc-2653	594	8	nk	nk	PROPN
dpc-2653	594	9	.	.	PUNCT
dpc-2653	594	10	cancer	cancer	NOUN
dpc-2653	594	11	chemotherapy	chemotherapy	NOUN
dpc-2653	594	12	and	and	CCONJ
dpc-2653	594	13	nail	nail	NOUN
dpc-2653	594	14	loss	loss	NOUN
dpc-2653	594	15	(	(	PUNCT
dpc-2653	594	16	onychomadesis	onychomadesis	NOUN
dpc-2653	594	17	)	)	PUNCT
dpc-2653	594	18	/	/	SYM
dpc-2653	594	19	meningeal	meningeal	ADJ
dpc-2653	594	20	relapse	relapse	NOUN
dpc-2653	594	21	in	in	ADP
dpc-2653	594	22	acute	acute	ADJ
dpc-2653	594	23	promyelocytic	promyelocytic	ADJ
dpc-2653	594	24	leukaemia	leukaemia	NOUN
dpc-2653	594	25	.	.	PUNCT
dpc-2653	595	1	acta	acta	PROPN
dpc-2653	595	2	haematol	haematol	PROPN
dpc-2653	595	3	.	.	PUNCT
dpc-2653	596	1	1983;70(2):137–137	1983;70(2):137–137	NUM
dpc-2653	596	2	.	.	PROPN
dpc-2653	597	1	62	62	NUM
dpc-2653	597	2	.	.	PUNCT
dpc-2653	598	1	ceyhan	ceyhan	PROPN
dpc-2653	598	2	am	be	AUX
dpc-2653	598	3	,	,	PUNCT
dpc-2653	598	4	yildirim	yildirim	PROPN
dpc-2653	598	5	m	m	PROPN
dpc-2653	598	6	,	,	PUNCT
dpc-2653	598	7	bircan	bircan	PROPN
dpc-2653	598	8	ha	ha	INTJ
dpc-2653	598	9	,	,	PUNCT
dpc-2653	598	10	karayigit	karayigit	ADJ
dpc-2653	598	11	dz	dz	PROPN
dpc-2653	598	12	.	.	PROPN
dpc-2653	598	13	transverse	transverse	PROPN
dpc-2653	598	14	leukonychia	leukonychia	PROPN
dpc-2653	598	15	(	(	PUNCT
dpc-2653	598	16	mees	mee	NOUN
dpc-2653	598	17	’	'	PUNCT
dpc-2653	598	18	lines	line	NOUN
dpc-2653	598	19	)	)	PUNCT
dpc-2653	598	20	associated	associate	VERB
dpc-2653	598	21	with	with	ADP
dpc-2653	598	22	docetaxel	docetaxel	PROPN
dpc-2653	598	23	.	.	PUNCT
dpc-2653	599	1	j	j	PROPN
dpc-2653	599	2	dermatol	dermatol	NOUN
dpc-2653	599	3	.	.	PUNCT
dpc-2653	600	1	2010;37(2):188–9	2010;37(2):188–9	NUM
dpc-2653	600	2	.	.	PUNCT
dpc-2653	601	1	63	63	NUM
dpc-2653	601	2	.	.	PUNCT
dpc-2653	602	1	parakh	parakh	PROPN
dpc-2653	602	2	a	a	PROPN
dpc-2653	602	3	,	,	PUNCT
dpc-2653	602	4	kocchar	kocchar	PROPN
dpc-2653	602	5	am	be	AUX
dpc-2653	602	6	.	.	PUNCT
dpc-2653	603	1	chemotherapy	chemotherapy	NOUN
dpc-2653	603	2	induced	induce	VERB
dpc-2653	603	3	transverse	transverse	NOUN
dpc-2653	603	4	leukonychia	leukonychia	NOUN
dpc-2653	603	5	(	(	PUNCT
dpc-2653	603	6	mees	mee	NOUN
dpc-2653	603	7	’	'	PUNCT
dpc-2653	603	8	lines	line	NOUN
dpc-2653	603	9	)	)	PUNCT
dpc-2653	603	10	.	.	PUNCT
dpc-2653	604	1	indian	indian	PROPN
dpc-2653	604	2	pediatr	pediatr	NOUN
dpc-2653	604	3	.	.	PUNCT
dpc-2653	605	1	2007;44(11):865	2007;44(11):865	PROPN
dpc-2653	605	2	.	.	PROPN
dpc-2653	605	3	64	64	NUM
dpc-2653	605	4	.	.	PUNCT
dpc-2653	606	1	mirfazaelian	mirfazaelian	ADJ
dpc-2653	606	2	h	h	NOUN
dpc-2653	606	3	,	,	PUNCT
dpc-2653	606	4	namazi	namazi	PROPN
dpc-2653	606	5	mr	mr	PROPN
dpc-2653	606	6	,	,	PUNCT
dpc-2653	606	7	daneshbod	daneshbod	PROPN
dpc-2653	606	8	y.	y.	PROPN
dpc-2653	606	9	mees	mees	PROPN
dpc-2653	606	10	’	'	PUNCT
dpc-2653	606	11	lines	line	NOUN
dpc-2653	606	12	.	.	PUNCT
dpc-2653	607	1	scientificworldjournal	scientificworldjournal	ADJ
dpc-2653	607	2	.	.	PUNCT
dpc-2653	608	1	2011;11:267–8	2011;11:267–8	NUM
dpc-2653	608	2	.	.	PUNCT
dpc-2653	609	1	65	65	NUM
dpc-2653	609	2	.	.	PUNCT
dpc-2653	610	1	kumar	kumar	PROPN
dpc-2653	610	2	s	s	PROPN
dpc-2653	610	3	,	,	PUNCT
dpc-2653	610	4	diwan	diwan	PROPN
dpc-2653	610	5	s	s	PROPN
dpc-2653	610	6	,	,	PUNCT
dpc-2653	610	7	dekate	dekate	PROPN
dpc-2653	610	8	m	m	PROPN
dpc-2653	610	9	,	,	PUNCT
dpc-2653	610	10	goyal	goyal	PROPN
dpc-2653	610	11	s.	s.	PROPN
dpc-2653	610	12	mees	mees	PROPN
dpc-2653	610	13	’	'	PUNCT
dpc-2653	610	14	line	line	NOUN
dpc-2653	610	15	following	follow	VERB
dpc-2653	610	16	chemotherapy	chemotherapy	NOUN
dpc-2653	610	17	.	.	PUNCT
dpc-2653	611	1	our	our	PRON
dpc-2653	611	2	dermatology	dermatology	NOUN
dpc-2653	611	3	online	online	ADV
dpc-2653	611	4	.	.	PUNCT
dpc-2653	612	1	2013;4(3):382–382	2013;4(3):382–382	X
dpc-2653	612	2	.	.	X
dpc-2653	612	3	66	66	NUM
dpc-2653	612	4	.	.	PUNCT
dpc-2653	613	1	shelley	shelley	PROPN
dpc-2653	613	2	wb	wb	PROPN
dpc-2653	613	3	,	,	PUNCT
dpc-2653	613	4	humphrey	humphrey	PROPN
dpc-2653	613	5	gb	gb	PROPN
dpc-2653	613	6	.	.	PUNCT
dpc-2653	614	1	transverse	transverse	NOUN
dpc-2653	614	2	leukonychia	leukonychia	PROPN
dpc-2653	614	3	(	(	PUNCT
dpc-2653	614	4	mees	mee	NOUN
dpc-2653	614	5	’	'	PUNCT
dpc-2653	614	6	lines	line	NOUN
dpc-2653	614	7	)	)	PUNCT
dpc-2653	614	8	due	due	ADP
dpc-2653	614	9	to	to	ADP
dpc-2653	614	10	daunorubicin	daunorubicin	PROPN
dpc-2653	614	11	chemotherapy	chemotherapy	NOUN
dpc-2653	614	12	.	.	PUNCT
dpc-2653	615	1	pediatr	pediatr	ADJ
dpc-2653	615	2	dermatol	dermatol	NOUN
dpc-2653	615	3	.	.	PUNCT
dpc-2653	616	1	1997;14(2):144–5	1997;14(2):144–5	NUM
dpc-2653	616	2	.	.	PUNCT
dpc-2653	617	1	67	67	NUM
dpc-2653	617	2	.	.	PUNCT
dpc-2653	617	3	alzahrani	alzahrani	PROPN
dpc-2653	617	4	mf	mf	PROPN
dpc-2653	617	5	,	,	PUNCT
dpc-2653	617	6	aljasser	aljasser	PROPN
dpc-2653	617	7	mi	mi	PROPN
dpc-2653	617	8	.	.	PROPN
dpc-2653	617	9	nail	nail	NOUN
dpc-2653	617	10	changes	change	NOUN
dpc-2653	617	11	during	during	ADP
dpc-2653	617	12	chemotherapy	chemotherapy	NOUN
dpc-2653	617	13	.	.	PUNCT
dpc-2653	618	1	n	n	PROPN
dpc-2653	618	2	engl	engl	PROPN
dpc-2653	618	3	j	j	PROPN
dpc-2653	618	4	med	med	PROPN
dpc-2653	618	5	.	.	PUNCT
dpc-2653	619	1	2018;379(16):1561–1561	2018;379(16):1561–1561	NUM
dpc-2653	619	2	.	.	X
dpc-2653	620	1	68	68	NUM
dpc-2653	620	2	.	.	PUNCT
dpc-2653	620	3	dasanu	dasanu	PROPN
dpc-2653	620	4	ca	ca	PROPN
dpc-2653	620	5	,	,	PUNCT
dpc-2653	620	6	vaillant	vaillant	ADJ
dpc-2653	620	7	jg	jg	PROPN
dpc-2653	620	8	,	,	PUNCT
dpc-2653	620	9	alexandrescu	alexandrescu	PROPN
dpc-2653	621	1	dt	dt	PROPN
dpc-2653	621	2	.	.	PUNCT
dpc-2653	622	1	distinct	distinct	ADJ
dpc-2653	622	2	patterns	pattern	NOUN
dpc-2653	622	3	of	of	ADP
dpc-2653	622	4	chromonychia	chromonychia	NOUN
dpc-2653	622	5	,	,	PUNCT
dpc-2653	622	6	beau	beau	PROPN
dpc-2653	622	7	’s	’s	PART
dpc-2653	622	8	lines	line	NOUN
dpc-2653	622	9	,	,	PUNCT
dpc-2653	622	10	and	and	CCONJ
dpc-2653	622	11	melanoderma	melanoderma	AUX
dpc-2653	622	12	seen	see	VERB
dpc-2653	622	13	with	with	ADP
dpc-2653	622	14	vincristine	vincristine	NOUN
dpc-2653	622	15	,	,	PUNCT
dpc-2653	622	16	adriamycin	adriamycin	PROPN
dpc-2653	622	17	,	,	PUNCT
dpc-2653	622	18	dexamethasone	dexamethasone	NOUN
dpc-2653	622	19	therapy	therapy	NOUN
dpc-2653	622	20	for	for	ADP
dpc-2653	622	21	multiple	multiple	ADJ
dpc-2653	622	22	myeloma	myeloma	NOUN
dpc-2653	622	23	.	.	PUNCT
dpc-2653	623	1	dermatol	dermatol	NOUN
dpc-2653	623	2	online	online	ADJ
dpc-2653	623	3	j.	j.	PROPN
dpc-2653	623	4	2006;12(6):5–7	2006;12(6):5–7	PROPN
dpc-2653	623	5	.	.	PUNCT
dpc-2653	624	1	69	69	NUM
dpc-2653	624	2	.	.	PUNCT
dpc-2653	625	1	scotté	scotté	PROPN
dpc-2653	625	2	f	f	PROPN
dpc-2653	625	3	,	,	PUNCT
dpc-2653	625	4	banu	banu	PROPN
dpc-2653	625	5	e	e	NOUN
dpc-2653	625	6	,	,	PUNCT
dpc-2653	625	7	medioni	medioni	PROPN
dpc-2653	625	8	j	j	PROPN
dpc-2653	625	9	,	,	PUNCT
dpc-2653	625	10	levy	levy	NOUN
dpc-2653	625	11	e	e	NOUN
dpc-2653	625	12	,	,	PUNCT
dpc-2653	625	13	ebenezer	ebenezer	PROPN
dpc-2653	625	14	c	c	PROPN
dpc-2653	625	15	,	,	PUNCT
dpc-2653	625	16	marsan	marsan	PROPN
dpc-2653	625	17	s	s	PROPN
dpc-2653	625	18	,	,	PUNCT
dpc-2653	625	19	et	et	PROPN
dpc-2653	625	20	al	al	PROPN
dpc-2653	625	21	.	.	PROPN
dpc-2653	625	22	matched	match	VERB
dpc-2653	625	23	case	case	NOUN
dpc-2653	625	24	-	-	PUNCT
dpc-2653	625	25	control	control	NOUN
dpc-2653	625	26	phase	phase	NOUN
dpc-2653	625	27	2	2	NUM
dpc-2653	625	28	study	study	NOUN
dpc-2653	625	29	to	to	PART
dpc-2653	625	30	evaluate	evaluate	VERB
dpc-2653	625	31	the	the	DET
dpc-2653	625	32	use	use	NOUN
dpc-2653	625	33	of	of	ADP
dpc-2653	625	34	a	a	DET
dpc-2653	625	35	frozen	frozen	ADJ
dpc-2653	625	36	sock	sock	NOUN
dpc-2653	625	37	to	to	PART
dpc-2653	625	38	prevent	prevent	VERB
dpc-2653	625	39	docetaxel	docetaxel	NOUN
dpc-2653	625	40	-	-	PUNCT
dpc-2653	625	41	induced	induce	VERB
dpc-2653	625	42	onycholysis	onycholysis	NOUN
dpc-2653	625	43	and	and	CCONJ
dpc-2653	625	44	cutaneous	cutaneous	ADJ
dpc-2653	625	45	toxicity	toxicity	NOUN
dpc-2653	625	46	of	of	ADP
dpc-2653	625	47	the	the	DET
dpc-2653	625	48	foot	foot	NOUN
dpc-2653	625	49	.	.	PUNCT
dpc-2653	626	1	cancer	cancer	NOUN
dpc-2653	626	2	.	.	PUNCT
dpc-2653	627	1	2008;112(7):1625–31	2008;112(7):1625–31	NUM
dpc-2653	627	2	.	.	PUNCT
dpc-2653	627	3	32	32	NUM
dpc-2653	627	4	.	.	PUNCT
dpc-2653	628	1	ko	ko	PROPN
dpc-2653	628	2	yj	yj	PROPN
dpc-2653	628	3	,	,	PUNCT
dpc-2653	628	4	canil	canil	PROPN
dpc-2653	628	5	cm	cm	PROPN
dpc-2653	628	6	,	,	PUNCT
dpc-2653	628	7	mukherjee	mukherjee	PROPN
dpc-2653	628	8	sd	sd	PROPN
dpc-2653	628	9	,	,	PUNCT
dpc-2653	628	10	winquist	winquist	NOUN
dpc-2653	628	11	e	e	NOUN
dpc-2653	628	12	,	,	PUNCT
dpc-2653	628	13	elser	elser	NOUN
dpc-2653	628	14	c	c	PROPN
dpc-2653	628	15	,	,	PUNCT
dpc-2653	628	16	eisen	eisen	NOUN
dpc-2653	628	17	a	a	PROPN
dpc-2653	628	18	,	,	PUNCT
dpc-2653	628	19	et	et	PROPN
dpc-2653	628	20	al	al	PROPN
dpc-2653	628	21	.	.	PROPN
dpc-2653	628	22	nanoparticle	nanoparticle	PROPN
dpc-2653	628	23	albumin	albumin	NOUN
dpc-2653	628	24	-	-	PUNCT
dpc-2653	628	25	bound	bind	VERB
dpc-2653	628	26	paclitaxel	paclitaxel	NOUN
dpc-2653	628	27	for	for	ADP
dpc-2653	628	28	second	second	ADJ
dpc-2653	628	29	-	-	PUNCT
dpc-2653	628	30	line	line	NOUN
dpc-2653	628	31	treatment	treatment	NOUN
dpc-2653	628	32	of	of	ADP
dpc-2653	628	33	metastatic	metastatic	ADJ
dpc-2653	628	34	urothelial	urothelial	ADJ
dpc-2653	628	35	carcinoma	carcinoma	NOUN
dpc-2653	628	36	:	:	PUNCT
dpc-2653	628	37	a	a	DET
dpc-2653	628	38	single	single	ADJ
dpc-2653	628	39	group	group	NOUN
dpc-2653	628	40	,	,	PUNCT
dpc-2653	628	41	multicentre	multicentre	NOUN
dpc-2653	628	42	,	,	PUNCT
dpc-2653	628	43	phase	phase	NOUN
dpc-2653	628	44	2	2	NUM
dpc-2653	628	45	study	study	NOUN
dpc-2653	628	46	.	.	PUNCT
dpc-2653	629	1	lancet	lancet	PROPN
dpc-2653	629	2	oncol	oncol	PROPN
dpc-2653	630	1	[	[	X
dpc-2653	630	2	internet	internet	NOUN
dpc-2653	630	3	]	]	PUNCT
dpc-2653	630	4	.	.	PUNCT
dpc-2653	631	1	2013;14(8):769–76	2013;14(8):769–76	X
dpc-2653	631	2	.	.	PUNCT
dpc-2653	631	3	available	available	ADJ
dpc-2653	631	4	from	from	ADP
dpc-2653	631	5	:	:	PUNCT
dpc-2653	631	6	http://dx.doi.org/10.1016/	http://dx.doi.org/10.1016/	NOUN
dpc-2653	631	7	s1470	s1470	PROPN
dpc-2653	631	8	-	-	PUNCT
dpc-2653	631	9	2045(13)70162	2045(13)70162	NUM
dpc-2653	631	10	-	-	PUNCT
dpc-2653	631	11	1	1	NUM
dpc-2653	631	12	33	33	NUM
dpc-2653	631	13	.	.	PUNCT
dpc-2653	632	1	yamamoto	yamamoto	PROPN
dpc-2653	632	2	y	y	PROPN
dpc-2653	632	3	,	,	PUNCT
dpc-2653	632	4	kawano	kawano	PROPN
dpc-2653	632	5	i	i	PRON
dpc-2653	632	6	,	,	PUNCT
dpc-2653	632	7	iwase	iwase	PROPN
dpc-2653	632	8	h.	h.	PROPN
dpc-2653	632	9	nab	nab	PROPN
dpc-2653	632	10	-	-	PUNCT
dpc-2653	632	11	paclitaxel	paclitaxel	PROPN
dpc-2653	632	12	for	for	ADP
dpc-2653	632	13	the	the	DET
dpc-2653	632	14	treatment	treatment	NOUN
dpc-2653	632	15	of	of	ADP
dpc-2653	632	16	breast	breast	NOUN
dpc-2653	632	17	cancer	cancer	NOUN
dpc-2653	632	18	:	:	PUNCT
dpc-2653	632	19	efficacy	efficacy	NOUN
dpc-2653	632	20	,	,	PUNCT
dpc-2653	632	21	safety	safety	NOUN
dpc-2653	632	22	,	,	PUNCT
dpc-2653	632	23	and	and	CCONJ
dpc-2653	632	24	approval	approval	NOUN
dpc-2653	632	25	.	.	PUNCT
dpc-2653	633	1	onco	onco	NOUN
dpc-2653	633	2	targets	target	NOUN
dpc-2653	633	3	ther	ther	ADV
dpc-2653	633	4	.	.	PUNCT
dpc-2653	634	1	2011;4:123–36	2011;4:123–36	NUM
dpc-2653	634	2	.	.	PUNCT
dpc-2653	635	1	34	34	NUM
dpc-2653	635	2	.	.	PUNCT
dpc-2653	636	1	schepisi	schepisi	VERB
dpc-2653	636	2	g	g	PROPN
dpc-2653	636	3	,	,	PUNCT
dpc-2653	636	4	conteduca	conteduca	NOUN
dpc-2653	636	5	v	v	NOUN
dpc-2653	636	6	,	,	PUNCT
dpc-2653	636	7	lolli	lolli	PROPN
dpc-2653	636	8	c	c	PROPN
dpc-2653	636	9	,	,	PUNCT
dpc-2653	636	10	medri	medri	NOUN
dpc-2653	636	11	m	m	PROPN
dpc-2653	636	12	,	,	PUNCT
dpc-2653	636	13	de	de	PROPN
dpc-2653	636	14	giorgi	giorgi	PROPN
dpc-2653	636	15	u.	u.	PROPN
dpc-2653	636	16	taxane	taxane	NOUN
dpc-2653	636	17	-	-	PUNCT
dpc-2653	636	18	related	relate	VERB
dpc-2653	636	19	nail	nail	NOUN
dpc-2653	636	20	toxicity	toxicity	NOUN
dpc-2653	636	21	.	.	PUNCT
dpc-2653	637	1	lancet	lancet	NOUN
dpc-2653	637	2	oncol	oncol	PROPN
dpc-2653	638	1	[	[	X
dpc-2653	638	2	internet	internet	NOUN
dpc-2653	638	3	]	]	PUNCT
dpc-2653	638	4	.	.	PUNCT
dpc-2653	639	1	2015;16(7):e310–1	2015;16(7):e310–1	X
dpc-2653	639	2	.	.	PUNCT
dpc-2653	640	1	available	available	ADJ
dpc-2653	640	2	from	from	ADP
dpc-2653	640	3	:	:	PUNCT
dpc-2653	640	4	http://dx.doi.org/10.1016/	http://dx.doi.org/10.1016/	PROPN
dpc-2653	640	5	s1470	s1470	PROPN
dpc-2653	640	6	-	-	PUNCT
dpc-2653	640	7	2045(15)00019	2045(15)00019	NUM
dpc-2653	640	8	-	-	SYM
dpc-2653	640	9	4	4	NUM
dpc-2653	640	10	35	35	NUM
dpc-2653	640	11	.	.	PUNCT
dpc-2653	641	1	capriotti	capriotti	PROPN
dpc-2653	641	2	k	k	PROPN
dpc-2653	641	3	,	,	PUNCT
dpc-2653	641	4	capriotti	capriotti	PROPN
dpc-2653	641	5	ja	ja	PROPN
dpc-2653	641	6	,	,	PUNCT
dpc-2653	641	7	lessin	lessin	PROPN
dpc-2653	641	8	s	s	PROPN
dpc-2653	641	9	,	,	PUNCT
dpc-2653	641	10	wu	wu	PROPN
dpc-2653	641	11	s	s	PROPN
dpc-2653	641	12	,	,	PUNCT
dpc-2653	641	13	goldfarb	goldfarb	PROPN
dpc-2653	641	14	s	s	PROPN
dpc-2653	641	15	,	,	PUNCT
dpc-2653	641	16	belum	belum	PROPN
dpc-2653	641	17	vr	vr	PROPN
dpc-2653	641	18	,	,	PUNCT
dpc-2653	641	19	et	et	PROPN
dpc-2653	641	20	al	al	PROPN
dpc-2653	641	21	.	.	PUNCT
dpc-2653	642	1	the	the	DET
dpc-2653	642	2	risk	risk	NOUN
dpc-2653	642	3	of	of	ADP
dpc-2653	642	4	nail	nail	NOUN
dpc-2653	642	5	changes	change	NOUN
dpc-2653	642	6	with	with	ADP
dpc-2653	642	7	taxane	taxane	NOUN
dpc-2653	642	8	chemotherapy	chemotherapy	NOUN
dpc-2653	642	9	:	:	PUNCT
dpc-2653	642	10	a	a	DET
dpc-2653	642	11	systematic	systematic	ADJ
dpc-2653	642	12	review	review	NOUN
dpc-2653	642	13	of	of	ADP
dpc-2653	642	14	the	the	DET
dpc-2653	642	15	literature	literature	NOUN
dpc-2653	642	16	and	and	CCONJ
dpc-2653	642	17	meta	meta	ADJ
dpc-2653	642	18	-	-	PUNCT
dpc-2653	642	19	analysis	analysis	NOUN
dpc-2653	642	20	.	.	PUNCT
dpc-2653	643	1	br	br	PROPN
dpc-2653	643	2	j	j	PROPN
dpc-2653	643	3	dermatol	dermatol	NOUN
dpc-2653	643	4	.	.	PUNCT
dpc-2653	644	1	2015;173(3):842–5	2015;173(3):842–5	NUM
dpc-2653	644	2	.	.	PUNCT
dpc-2653	645	1	36	36	NUM
dpc-2653	645	2	.	.	PUNCT
dpc-2653	646	1	sanmartín	sanmartín	PROPN
dpc-2653	646	2	o	o	PROPN
dpc-2653	646	3	,	,	PUNCT
dpc-2653	646	4	beato	beato	PROPN
dpc-2653	646	5	c	c	X
dpc-2653	646	6	,	,	PUNCT
dpc-2653	646	7	suh	suh	PROPN
dpc-2653	646	8	-	-	PUNCT
dpc-2653	646	9	oh	oh	PROPN
dpc-2653	646	10	hj	hj	PROPN
dpc-2653	646	11	,	,	PUNCT
dpc-2653	646	12	aragón	aragón	PROPN
dpc-2653	646	13	i	i	PRON
dpc-2653	646	14	,	,	PUNCT
dpc-2653	646	15	españa	españa	X
dpc-2653	646	16	a	a	PRON
dpc-2653	646	17	,	,	PUNCT
dpc-2653	646	18	majem	majem	NOUN
dpc-2653	646	19	m	m	PROPN
dpc-2653	646	20	,	,	PUNCT
dpc-2653	646	21	et	et	PROPN
dpc-2653	646	22	al	al	PROPN
dpc-2653	646	23	.	.	PROPN
dpc-2653	647	1	clinical	clinical	ADJ
dpc-2653	647	2	management	management	NOUN
dpc-2653	647	3	of	of	ADP
dpc-2653	647	4	cutaneous	cutaneous	ADJ
dpc-2653	647	5	adverse	adverse	ADJ
dpc-2653	647	6	events	event	NOUN
dpc-2653	647	7	in	in	ADP
dpc-2653	647	8	patients	patient	NOUN
dpc-2653	647	9	on	on	ADP
dpc-2653	647	10	chemotherapy	chemotherapy	NOUN
dpc-2653	647	11	:	:	PUNCT
dpc-2653	647	12	a	a	DET
dpc-2653	647	13	national	national	ADJ
dpc-2653	647	14	consensus	consensus	NOUN
dpc-2653	647	15	statement	statement	NOUN
dpc-2653	647	16	by	by	ADP
dpc-2653	647	17	the	the	DET
dpc-2653	647	18	spanish	spanish	ADJ
dpc-2653	647	19	academy	academy	NOUN
dpc-2653	647	20	of	of	ADP
dpc-2653	647	21	dermatology	dermatology	NOUN
dpc-2653	647	22	and	and	CCONJ
dpc-2653	647	23	venereology	venereology	NOUN
dpc-2653	647	24	and	and	CCONJ
dpc-2653	647	25	the	the	DET
dpc-2653	647	26	spanish	spanish	ADJ
dpc-2653	647	27	society	society	NOUN
dpc-2653	647	28	of	of	ADP
dpc-2653	647	29	medical	medical	ADJ
dpc-2653	647	30	oncology	oncology	NOUN
dpc-2653	647	31	.	.	PUNCT
dpc-2653	648	1	actas	actas	PROPN
dpc-2653	648	2	dermosifiliogr	dermosifiliogr	NOUN
dpc-2653	648	3	.	.	PUNCT
dpc-2653	649	1	2019;110(6):448–59	2019;110(6):448–59	NUM
dpc-2653	649	2	.	.	PUNCT
dpc-2653	650	1	37	37	NUM
dpc-2653	650	2	.	.	PUNCT
dpc-2653	651	1	rubin	rubin	PROPN
dpc-2653	651	2	ai	ai	PROPN
dpc-2653	651	3	,	,	PUNCT
dpc-2653	651	4	jellinek	jellinek	PROPN
dpc-2653	651	5	nj	nj	PROPN
dpc-2653	651	6	,	,	PUNCT
dpc-2653	651	7	ralph	ralph	PROPN
dpc-2653	651	8	daniel	daniel	PROPN
dpc-2653	651	9	c	c	PROPN
dpc-2653	651	10	,	,	PUNCT
dpc-2653	651	11	scher	scher	PROPN
dpc-2653	651	12	rk	rk	PROPN
dpc-2653	651	13	.	.	PROPN
dpc-2653	651	14	scher	scher	PROPN
dpc-2653	651	15	and	and	CCONJ
dpc-2653	651	16	daniel	daniel	PROPN
dpc-2653	651	17	’s	’s	PART
dpc-2653	651	18	nails	nail	NOUN
dpc-2653	651	19	:	:	PUNCT
dpc-2653	651	20	diagnosis	diagnosis	NOUN
dpc-2653	651	21	,	,	PUNCT
dpc-2653	651	22	surgery	surgery	NOUN
dpc-2653	651	23	,	,	PUNCT
dpc-2653	651	24	therapy	therapy	NOUN
dpc-2653	651	25	:	:	PUNCT
dpc-2653	651	26	fourth	fourth	PROPN
dpc-2653	651	27	edition	edition	PROPN
dpc-2653	651	28	.	.	PUNCT
dpc-2653	652	1	scher	scher	PROPN
dpc-2653	652	2	daniel	daniel	PROPN
dpc-2653	652	3	’s	’s	PART
dpc-2653	652	4	nails	nail	NOUN
dpc-2653	652	5	diagnosis	diagnosis	NOUN
dpc-2653	652	6	,	,	PUNCT
dpc-2653	652	7	surgery	surgery	NOUN
dpc-2653	652	8	,	,	PUNCT
dpc-2653	652	9	ther	ther	ADV
dpc-2653	652	10	fourth	fourth	ADJ
dpc-2653	652	11	ed	ed	NOUN
dpc-2653	652	12	.	.	PUNCT
dpc-2653	652	13	2018;1–665	2018;1–665	NUM
dpc-2653	652	14	.	.	PUNCT
dpc-2653	653	1	38	38	NUM
dpc-2653	653	2	.	.	PUNCT
dpc-2653	654	1	baran	baran	PROPN
dpc-2653	654	2	&	&	CCONJ
dpc-2653	654	3	dawber	dawber	PROPN
dpc-2653	654	4	’s	’s	PART
dpc-2653	654	5	diseases	disease	NOUN
dpc-2653	654	6	of	of	ADP
dpc-2653	654	7	the	the	DET
dpc-2653	654	8	nails	nail	NOUN
dpc-2653	654	9	and	and	CCONJ
dpc-2653	654	10	their	their	PRON
dpc-2653	654	11	management	management	NOUN
dpc-2653	654	12	.	.	PUNCT
dpc-2653	655	1	vol	vol	NOUN
dpc-2653	655	2	.	.	PROPN
dpc-2653	656	1	1	1	NUM
dpc-2653	656	2	,	,	PUNCT
dpc-2653	656	3	journal	journal	NOUN
dpc-2653	656	4	of	of	ADP
dpc-2653	656	5	cosmetic	cosmetic	ADJ
dpc-2653	656	6	dermatology	dermatology	NOUN
dpc-2653	656	7	.	.	PUNCT
dpc-2653	657	1	2002	2002	NUM
dpc-2653	657	2	.	.	PUNCT
dpc-2653	658	1	103–103	103–103	NUM
dpc-2653	658	2	p.	p.	NOUN
dpc-2653	658	3	39	39	NUM
dpc-2653	658	4	.	.	PUNCT
dpc-2653	659	1	eng	eng	PROPN
dpc-2653	659	2	ht	ht	PROPN
dpc-2653	659	3	,	,	PUNCT
dpc-2653	659	4	chan	chan	PROPN
dpc-2653	659	5	a.	a.	PROPN
dpc-2653	659	6	evidence	evidence	NOUN
dpc-2653	659	7	-	-	PUNCT
dpc-2653	659	8	based	base	VERB
dpc-2653	659	9	treatment	treatment	NOUN
dpc-2653	659	10	options	option	NOUN
dpc-2653	659	11	for	for	ADP
dpc-2653	659	12	the	the	DET
dpc-2653	659	13	management	management	NOUN
dpc-2653	659	14	of	of	ADP
dpc-2653	659	15	skin	skin	NOUN
dpc-2653	659	16	toxicities	toxicity	NOUN
dpc-2653	659	17	associated	associate	VERB
dpc-2653	659	18	with	with	ADP
dpc-2653	659	19	epidermal	epidermal	ADJ
dpc-2653	659	20	growth	growth	NOUN
dpc-2653	659	21	factor	factor	NOUN
dpc-2653	659	22	receptor	receptor	NOUN
dpc-2653	659	23	inhibitors	inhibitor	NOUN
dpc-2653	659	24	.	.	PUNCT
dpc-2653	660	1	ann	ann	PROPN
dpc-2653	660	2	pharmacother	pharmacother	PROPN
dpc-2653	660	3	.	.	PUNCT
dpc-2653	661	1	2009;43(10):1658–66	2009;43(10):1658–66	NUM
dpc-2653	661	2	.	.	NOUN
dpc-2653	662	1	40	40	NUM
dpc-2653	662	2	.	.	PUNCT
dpc-2653	663	1	lacouture	lacouture	NOUN
dpc-2653	663	2	me	i	PRON
dpc-2653	663	3	,	,	PUNCT
dpc-2653	663	4	anadkat	anadkat	PROPN
dpc-2653	663	5	mj	mj	PROPN
dpc-2653	663	6	,	,	PUNCT
dpc-2653	663	7	bensadoun	bensadoun	PROPN
dpc-2653	663	8	rj	rj	PROPN
dpc-2653	663	9	,	,	PUNCT
dpc-2653	663	10	bryce	bryce	PROPN
dpc-2653	663	11	j	j	PROPN
dpc-2653	663	12	,	,	PUNCT
dpc-2653	663	13	chan	chan	PROPN
dpc-2653	663	14	a	a	PROPN
dpc-2653	663	15	,	,	PUNCT
dpc-2653	663	16	epstein	epstein	PROPN
dpc-2653	663	17	jb	jb	PROPN
dpc-2653	663	18	,	,	PUNCT
dpc-2653	663	19	et	et	PROPN
dpc-2653	663	20	al	al	PROPN
dpc-2653	663	21	.	.	PROPN
dpc-2653	664	1	clinical	clinical	ADJ
dpc-2653	664	2	practice	practice	NOUN
dpc-2653	664	3	guidelines	guideline	NOUN
dpc-2653	664	4	for	for	ADP
dpc-2653	664	5	the	the	DET
dpc-2653	664	6	prevention	prevention	NOUN
dpc-2653	664	7	and	and	CCONJ
dpc-2653	664	8	treatment	treatment	NOUN
dpc-2653	664	9	of	of	ADP
dpc-2653	664	10	egfr	egfr	ADJ
dpc-2653	664	11	inhibitor	inhibitor	NOUN
dpc-2653	664	12	-	-	PUNCT
dpc-2653	664	13	associated	associate	VERB
dpc-2653	664	14	dermatologic	dermatologic	ADJ
dpc-2653	664	15	toxicities	toxicity	NOUN
dpc-2653	664	16	.	.	PUNCT
dpc-2653	665	1	support	support	NOUN
dpc-2653	665	2	care	care	NOUN
dpc-2653	665	3	cancer	cancer	NOUN
dpc-2653	665	4	.	.	PUNCT
dpc-2653	666	1	2011;19(8):1079–95	2011;19(8):1079–95	NOUN
dpc-2653	666	2	.	.	PUNCT
dpc-2653	667	1	41	41	NUM
dpc-2653	667	2	.	.	PUNCT
dpc-2653	668	1	reyes	reyes	PROPN
dpc-2653	668	2	-	-	PUNCT
dpc-2653	668	3	habito	habito	PROPN
dpc-2653	668	4	cm	cm	PROPN
dpc-2653	668	5	,	,	PUNCT
dpc-2653	668	6	roh	roh	PROPN
dpc-2653	668	7	ek	ek	PROPN
dpc-2653	668	8	.	.	PROPN
dpc-2653	668	9	cutaneous	cutaneous	ADJ
dpc-2653	668	10	reactions	reaction	NOUN
dpc-2653	668	11	to	to	ADP
dpc-2653	668	12	chemotherapeutic	chemotherapeutic	ADJ
dpc-2653	668	13	drugs	drug	NOUN
dpc-2653	668	14	and	and	CCONJ
dpc-2653	668	15	targeted	target	VERB
dpc-2653	668	16	therapy	therapy	NOUN
dpc-2653	668	17	for	for	ADP
dpc-2653	668	18	cancer	cancer	NOUN
dpc-2653	668	19	:	:	PUNCT
dpc-2653	668	20	part	part	PROPN
dpc-2653	668	21	ii	ii	PROPN
dpc-2653	668	22	.	.	PUNCT
dpc-2653	668	23	targeted	target	VERB
dpc-2653	668	24	therapy	therapy	NOUN
dpc-2653	668	25	.	.	PUNCT
dpc-2653	669	1	j	j	PROPN
dpc-2653	669	2	am	be	AUX
dpc-2653	669	3	acad	acad	X
dpc-2653	669	4	dermatol	dermatol	NOUN
dpc-2653	670	1	[	[	X
dpc-2653	670	2	internet	internet	NOUN
dpc-2653	670	3	]	]	PUNCT
dpc-2653	670	4	.	.	PUNCT
dpc-2653	671	1	2014;71(2):217	2014;71(2):217	NOUN
dpc-2653	671	2	.	.	PUNCT
dpc-2653	672	1	e1	e1	NOUN
dpc-2653	672	2	-	-	PUNCT
dpc-2653	672	3	217.e11	217.e11	PROPN
dpc-2653	672	4	.	.	PUNCT
dpc-2653	672	5	available	available	ADJ
dpc-2653	672	6	from	from	ADP
dpc-2653	672	7	:	:	PUNCT
dpc-2653	672	8	http://dx.doi.org/10.1016/j	http://dx.doi.org/10.1016/j	PROPN
dpc-2653	672	9	.	.	PUNCT
dpc-2653	672	10	jaad.2014.04.013	jaad.2014.04.013	PRON
dpc-2653	672	11	42	42	NUM
dpc-2653	672	12	.	.	PUNCT
dpc-2653	673	1	apalla	apalla	PROPN
dpc-2653	673	2	z	z	PROPN
dpc-2653	673	3	,	,	PUNCT
dpc-2653	673	4	papageorgiou	papageorgiou	NOUN
dpc-2653	673	5	c	c	NOUN
dpc-2653	673	6	,	,	PUNCT
dpc-2653	673	7	lallas	lallas	PROPN
dpc-2653	673	8	a	a	PRON
dpc-2653	673	9	,	,	PUNCT
dpc-2653	673	10	delli	delli	PROPN
dpc-2653	673	11	f	f	NOUN
dpc-2653	673	12	,	,	PUNCT
dpc-2653	673	13	fotiadou	fotiadou	PROPN
dpc-2653	673	14	c	c	PROPN
dpc-2653	673	15	,	,	PUNCT
dpc-2653	673	16	kemanetzi	kemanetzi	NOUN
dpc-2653	673	17	c	c	NOUN
dpc-2653	673	18	,	,	PUNCT
dpc-2653	673	19	et	et	PROPN
dpc-2653	673	20	al	al	PROPN
dpc-2653	673	21	.	.	PUNCT
dpc-2653	674	1	cutaneous	cutaneous	ADJ
dpc-2653	674	2	adverse	adverse	ADJ
dpc-2653	674	3	events	event	NOUN
dpc-2653	674	4	of	of	ADP
dpc-2653	674	5	immune	immune	ADJ
dpc-2653	674	6	checkpoint	checkpoint	NOUN
dpc-2653	674	7	inhibitors	inhibitor	NOUN
dpc-2653	674	8	:	:	PUNCT
dpc-2653	674	9	a	a	DET
dpc-2653	674	10	literature	literature	NOUN
dpc-2653	674	11	review	review	NOUN
dpc-2653	674	12	.	.	PUNCT
dpc-2653	675	1	dermatol	dermatol	NOUN
dpc-2653	675	2	pract	pract	PROPN
dpc-2653	675	3	concept	concept	NOUN
dpc-2653	675	4	.	.	PUNCT
dpc-2653	676	1	2021;11(1):e2021155	2021;11(1):e2021155	X
dpc-2653	676	2	.	.	NOUN
dpc-2653	676	3	43	43	NUM
dpc-2653	676	4	.	.	PUNCT
dpc-2653	677	1	acad	acad	PROPN
dpc-2653	677	2	dermatol	dermatol	NOUN
dpc-2653	677	3	venereol	venereol	NOUN
dpc-2653	677	4	2021	2021	NUM
dpc-2653	677	5	apalla	apalla	PROPN
dpc-2653	677	6	european	european	ADJ
dpc-2653	677	7	recommendations	recommendation	NOUN
dpc-2653	677	8	for	for	ADP
dpc-2653	677	9	management	management	NOUN
dpc-2653	677	10	of	of	ADP
dpc-2653	677	11	immune	immune	ADJ
dpc-2653	677	12	checkpoint	checkpoint	NOUN
dpc-2653	677	13	inhibitors-derived.pdf	inhibitors-derived.pdf	NOUN
dpc-2653	677	14	.	.	PUNCT
dpc-2653	678	1	44	44	NUM
dpc-2653	678	2	.	.	PUNCT
dpc-2653	679	1	sibaud	sibaud	PROPN
dpc-2653	679	2	v	v	PROPN
dpc-2653	679	3	,	,	PUNCT
dpc-2653	679	4	meyer	meyer	PROPN
dpc-2653	679	5	n	n	CCONJ
dpc-2653	679	6	,	,	PUNCT
dpc-2653	679	7	lamant	lamant	PROPN
dpc-2653	679	8	l	l	NOUN
dpc-2653	679	9	,	,	PUNCT
dpc-2653	679	10	vigarios	vigarios	PROPN
dpc-2653	679	11	e	e	NOUN
dpc-2653	679	12	,	,	PUNCT
dpc-2653	679	13	mazieres	mazieres	PROPN
dpc-2653	679	14	j	j	PROPN
dpc-2653	679	15	,	,	PUNCT
dpc-2653	679	16	delord	delord	PROPN
dpc-2653	679	17	jp	jp	NOUN
dpc-2653	679	18	.	.	PUNCT
dpc-2653	680	1	dermatologic	dermatologic	ADJ
dpc-2653	680	2	complications	complication	NOUN
dpc-2653	680	3	of	of	ADP
dpc-2653	680	4	anti	anti	ADJ
dpc-2653	680	5	-	-	ADJ
dpc-2653	680	6	pd-1	pd-1	ADJ
dpc-2653	680	7	/	/	SYM
dpc-2653	680	8	pd	pd	ADJ
dpc-2653	680	9	-	-	PUNCT
dpc-2653	680	10	l1	l1	PROPN
dpc-2653	680	11	immune	immune	ADJ
dpc-2653	680	12	checkpoint	checkpoint	NOUN
dpc-2653	680	13	antibodies	antibodie	VERB
dpc-2653	680	14	.	.	PUNCT
dpc-2653	681	1	curr	curr	PROPN
dpc-2653	681	2	opin	opin	PROPN
dpc-2653	681	3	oncol	oncol	PROPN
dpc-2653	681	4	.	.	PUNCT
dpc-2653	682	1	2016;28(4):254–63	2016;28(4):254–63	NUM
dpc-2653	682	2	.	.	NOUN
dpc-2653	682	3	45	45	NUM
dpc-2653	682	4	.	.	PUNCT
dpc-2653	683	1	sibaud	sibaud	NOUN
dpc-2653	683	2	v.	v.	ADP
dpc-2653	683	3	dermatologic	dermatologic	ADJ
dpc-2653	683	4	reactions	reaction	NOUN
dpc-2653	683	5	to	to	ADP
dpc-2653	683	6	immune	immune	ADJ
dpc-2653	683	7	checkpoint	checkpoint	NOUN
dpc-2653	683	8	inhibitors	inhibitor	NOUN
dpc-2653	683	9	:	:	PUNCT
dpc-2653	683	10	skin	skin	NOUN
dpc-2653	683	11	toxicities	toxicity	NOUN
dpc-2653	683	12	and	and	CCONJ
dpc-2653	683	13	immunotherapy	immunotherapy	NOUN
dpc-2653	683	14	.	.	PUNCT
dpc-2653	684	1	am	be	AUX
dpc-2653	684	2	j	j	PROPN
dpc-2653	684	3	clin	clin	PROPN
dpc-2653	684	4	dermatol	dermatol	NOUN
dpc-2653	685	1	[	[	X
dpc-2653	685	2	internet	internet	NOUN
dpc-2653	685	3	]	]	PUNCT
dpc-2653	685	4	.	.	PUNCT
dpc-2653	686	1	2018;19(3):345–61	2018;19(3):345–61	X
dpc-2653	686	2	.	.	PUNCT
dpc-2653	687	1	available	available	ADJ
dpc-2653	687	2	from	from	ADP
dpc-2653	687	3	:	:	PUNCT
dpc-2653	687	4	https://doi	https://doi	PROPN
dpc-2653	687	5	.	.	PUNCT
dpc-2653	687	6	org/10.1007	org/10.1007	PROPN
dpc-2653	687	7	/	/	SYM
dpc-2653	687	8	s40257	s40257	NOUN
dpc-2653	687	9	-	-	PUNCT
dpc-2653	687	10	017	017	NUM
dpc-2653	687	11	-	-	PUNCT
dpc-2653	687	12	0336	0336	NUM
dpc-2653	687	13	-	-	SYM
dpc-2653	687	14	3	3	NUM
dpc-2653	687	15	46	46	NUM
dpc-2653	687	16	.	.	PUNCT
dpc-2653	688	1	gilbar	gilbar	PROPN
dpc-2653	688	2	p	p	PROPN
dpc-2653	688	3	,	,	PUNCT
dpc-2653	688	4	hain	hain	PROPN
dpc-2653	688	5	a	a	PRON
dpc-2653	688	6	,	,	PUNCT
dpc-2653	688	7	peereboom	peereboom	NOUN
dpc-2653	688	8	veta	veta	PROPN
dpc-2653	688	9	-	-	PUNCT
dpc-2653	688	10	marie	marie	PROPN
dpc-2653	688	11	vm	vm	PROPN
dpc-2653	688	12	.	.	PROPN
dpc-2653	688	13	nail	nail	NOUN
dpc-2653	688	14	toxicity	toxicity	NOUN
dpc-2653	688	15	induced	induce	VERB
dpc-2653	688	16	by	by	ADP
dpc-2653	688	17	cancer	cancer	NOUN
dpc-2653	688	18	chemotherapy	chemotherapy	NOUN
dpc-2653	688	19	.	.	PUNCT
dpc-2653	689	1	j	j	PROPN
dpc-2653	689	2	oncol	oncol	ADJ
dpc-2653	689	3	pharm	pharm	NOUN
dpc-2653	689	4	pract	pract	NOUN
dpc-2653	689	5	.	.	PUNCT
dpc-2653	690	1	2009;15(3):143–55	2009;15(3):143–55	X
dpc-2653	690	2	.	.	PUNCT
dpc-2653	691	1	47	47	NUM
dpc-2653	691	2	.	.	PUNCT
dpc-2653	692	1	piraccini	piraccini	PROPN
dpc-2653	692	2	bm	bm	PROPN
dpc-2653	692	3	,	,	PUNCT
dpc-2653	692	4	alessandrini	alessandrini	PROPN
dpc-2653	692	5	a.	a.	NOUN
dpc-2653	692	6	drug	drug	NOUN
dpc-2653	692	7	-	-	PUNCT
dpc-2653	692	8	related	relate	VERB
dpc-2653	692	9	nail	nail	NOUN
dpc-2653	692	10	disease	disease	NOUN
dpc-2653	692	11	.	.	PUNCT
dpc-2653	693	1	clin	clin	PROPN
dpc-2653	693	2	dermatol	dermatol	NOUN
dpc-2653	694	1	[	[	X
dpc-2653	694	2	internet	internet	NOUN
dpc-2653	694	3	]	]	PUNCT
dpc-2653	694	4	.	.	PUNCT
dpc-2653	695	1	2013;31(5):618–26	2013;31(5):618–26	NUM
dpc-2653	695	2	.	.	PUNCT
dpc-2653	695	3	available	available	ADJ
dpc-2653	695	4	from	from	ADP
dpc-2653	695	5	:	:	PUNCT
dpc-2653	695	6	http://	http://	PROPN
dpc-2653	695	7	dx.doi.org/10.1016/j.clindermatol.2013.06.013	dx.doi.org/10.1016/j.clindermatol.2013.06.013	ADJ
dpc-2653	695	8	18	18	NUM
dpc-2653	695	9	review	review	NOUN
dpc-2653	695	10	|	|	ADV
dpc-2653	695	11	dermatol	dermatol	ADJ
dpc-2653	695	12	pract	pract	NOUN
dpc-2653	695	13	concept	concept	NOUN
dpc-2653	695	14	.	.	PUNCT
dpc-2653	696	1	2023;13(1):e2023064	2023;13(1):e2023064	NUM
dpc-2653	696	2	70	70	NUM
dpc-2653	696	3	.	.	PUNCT
dpc-2653	697	1	mackay	mackay	PROPN
dpc-2653	697	2	-	-	PUNCT
dpc-2653	697	3	wiggan	wiggan	PROPN
dpc-2653	697	4	j	j	PROPN
dpc-2653	697	5	,	,	PUNCT
dpc-2653	697	6	nair	nair	PROPN
dpc-2653	697	7	kg	kg	PROPN
dpc-2653	697	8	,	,	PUNCT
dpc-2653	697	9	halasz	halasz	NOUN
dpc-2653	697	10	clg	clg	NOUN
dpc-2653	697	11	.	.	PUNCT
dpc-2653	698	1	onycholysis	onycholysis	NOUN
dpc-2653	698	2	associated	associate	VERB
dpc-2653	698	3	with	with	ADP
dpc-2653	698	4	paclitaxel	paclitaxel	PROPN
dpc-2653	698	5	.	.	PUNCT
dpc-2653	699	1	cutis	cutis	NOUN
dpc-2653	699	2	.	.	PUNCT
dpc-2653	700	1	2003;71(3):229–32	2003;71(3):229–32	NUM
dpc-2653	700	2	.	.	PUNCT
dpc-2653	701	1	71	71	NUM
dpc-2653	701	2	.	.	PUNCT
dpc-2653	702	1	ghetti	ghetti	PROPN
dpc-2653	702	2	e	e	PROPN
dpc-2653	702	3	,	,	PUNCT
dpc-2653	702	4	piraccini	piraccini	PROPN
dpc-2653	702	5	bm	bm	PROPN
dpc-2653	702	6	,	,	PUNCT
dpc-2653	702	7	tosti	tosti	PROPN
dpc-2653	702	8	a.	a.	NOUN
dpc-2653	702	9	onycholysis	onycholysis	PROPN
dpc-2653	702	10	and	and	CCONJ
dpc-2653	702	11	subungual	subungual	ADJ
dpc-2653	702	12	haemorrhages	haemorrhage	NOUN
dpc-2653	702	13	secondary	secondary	ADJ
dpc-2653	702	14	to	to	ADP
dpc-2653	702	15	systemic	systemic	ADJ
dpc-2653	702	16	chemotherapy	chemotherapy	NOUN
dpc-2653	702	17	(	(	PUNCT
dpc-2653	702	18	paclitaxel	paclitaxel	PROPN
dpc-2653	702	19	)	)	PUNCT
dpc-2653	702	20	.	.	PUNCT
dpc-2653	703	1	j	j	PROPN
dpc-2653	703	2	 	 	SPACE
dpc-2653	703	3	eur	eur	PROPN
dpc-2653	703	4	acad	acad	PROPN
dpc-2653	703	5	dermatology	dermatology	NOUN
dpc-2653	703	6	venereol	venereol	NOUN
dpc-2653	703	7	.	.	PUNCT
dpc-2653	704	1	2003;17(4):459–60	2003;17(4):459–60	NUM
dpc-2653	704	2	.	.	PUNCT
dpc-2653	705	1	72	72	NUM
dpc-2653	705	2	.	.	PUNCT
dpc-2653	706	1	link	link	PROPN
dpc-2653	706	2	cj	cj	PROPN
dpc-2653	706	3	,	,	PUNCT
dpc-2653	706	4	sarosy	sarosy	PROPN
dpc-2653	706	5	ga	ga	PROPN
dpc-2653	706	6	,	,	PUNCT
dpc-2653	706	7	kohn	kohn	PROPN
dpc-2653	706	8	ec	ec	PROPN
dpc-2653	706	9	,	,	PUNCT
dpc-2653	706	10	christian	christian	PROPN
dpc-2653	706	11	mc	mc	PROPN
dpc-2653	706	12	,	,	PUNCT
dpc-2653	706	13	davis	davis	PROPN
dpc-2653	706	14	p	p	PROPN
dpc-2653	706	15	,	,	PUNCT
dpc-2653	706	16	adamo	adamo	PROPN
dpc-2653	706	17	do	do	PROPN
dpc-2653	706	18	,	,	PUNCT
dpc-2653	706	19	et	et	PROPN
dpc-2653	706	20	al	al	PROPN
dpc-2653	706	21	.	.	PUNCT
dpc-2653	707	1	cutaneous	cutaneous	ADJ
dpc-2653	707	2	manifestations	manifestation	NOUN
dpc-2653	707	3	of	of	ADP
dpc-2653	707	4	taxol	taxol	NOUN
dpc-2653	707	5	®	®	NOUN
dpc-2653	707	6	therapy	therapy	NOUN
dpc-2653	707	7	.	.	PUNCT
dpc-2653	708	1	invest	invest	VERB
dpc-2653	708	2	new	new	ADJ
dpc-2653	708	3	drugs	drug	NOUN
dpc-2653	708	4	.	.	PUNCT
dpc-2653	709	1	1995;13(3):261–3	1995;13(3):261–3	NUM
dpc-2653	709	2	.	.	PUNCT
dpc-2653	710	1	73	73	NUM
dpc-2653	710	2	.	.	PUNCT
dpc-2653	711	1	wasner	wasner	NOUN
dpc-2653	711	2	g	g	NOUN
dpc-2653	711	3	,	,	PUNCT
dpc-2653	711	4	hilpert	hilpert	NOUN
dpc-2653	711	5	f	f	PROPN
dpc-2653	711	6	,	,	PUNCT
dpc-2653	711	7	baron	baron	ADJ
dpc-2653	711	8	r	r	NOUN
dpc-2653	711	9	,	,	PUNCT
dpc-2653	711	10	pfisterer	pfisterer	NOUN
dpc-2653	711	11	j.	j.	PROPN
dpc-2653	711	12	clinical	clinical	ADJ
dpc-2653	711	13	picture	picture	NOUN
dpc-2653	711	14	:	:	PUNCT
dpc-2653	711	15	nail	nail	NOUN
dpc-2653	711	16	changes	change	NOUN
dpc-2653	711	17	secondary	secondary	ADJ
dpc-2653	711	18	to	to	ADP
dpc-2653	711	19	docetaxel	docetaxel	PROPN
dpc-2653	711	20	.	.	PUNCT
dpc-2653	712	1	lancet	lancet	PROPN
dpc-2653	712	2	.	.	PUNCT
dpc-2653	713	1	2001;357(9260):910	2001;357(9260):910	NUM
dpc-2653	713	2	.	.	X
dpc-2653	714	1	74	74	NUM
dpc-2653	714	2	.	.	PUNCT
dpc-2653	715	1	shemer	shemer	PROPN
dpc-2653	715	2	a	a	PROPN
dpc-2653	715	3	,	,	PUNCT
dpc-2653	715	4	daniel	daniel	PROPN
dpc-2653	715	5	cr	cr	PROPN
dpc-2653	715	6	.	.	PUNCT
dpc-2653	716	1	common	common	ADJ
dpc-2653	716	2	nail	nail	NOUN
dpc-2653	716	3	disorders	disorder	NOUN
dpc-2653	716	4	.	.	PUNCT
dpc-2653	717	1	clin	clin	PROPN
dpc-2653	717	2	dermatol	dermatol	NOUN
dpc-2653	717	3	.	.	PUNCT
dpc-2653	718	1	2013;31(5):578–86	2013;31(5):578–86	NUM
dpc-2653	718	2	.	.	PUNCT
dpc-2653	719	1	75	75	NUM
dpc-2653	719	2	.	.	PUNCT
dpc-2653	720	1	boucher	boucher	PROPN
dpc-2653	720	2	kw	kw	PROPN
dpc-2653	720	3	,	,	PUNCT
dpc-2653	720	4	davidson	davidson	PROPN
dpc-2653	720	5	k	k	PROPN
dpc-2653	720	6	,	,	PUNCT
dpc-2653	720	7	mirakhur	mirakhur	PROPN
dpc-2653	720	8	b	b	PROPN
dpc-2653	720	9	,	,	PUNCT
dpc-2653	720	10	goldberg	goldberg	PROPN
dpc-2653	720	11	j	j	PROPN
dpc-2653	720	12	,	,	PUNCT
dpc-2653	720	13	heymann	heymann	PROPN
dpc-2653	720	14	wr	wr	PROPN
dpc-2653	720	15	.	.	PUNCT
dpc-2653	721	1	paronychia	paronychia	PROPN
dpc-2653	721	2	induced	induce	VERB
dpc-2653	721	3	by	by	ADP
dpc-2653	721	4	cetuximab	cetuximab	NOUN
dpc-2653	721	5	,	,	PUNCT
dpc-2653	721	6	an	an	DET
dpc-2653	721	7	antiepidermal	antiepidermal	ADJ
dpc-2653	721	8	growth	growth	NOUN
dpc-2653	721	9	factor	factor	NOUN
dpc-2653	721	10	receptor	receptor	NOUN
dpc-2653	721	11	antibody	antibody	NOUN
dpc-2653	721	12	.	.	PUNCT
dpc-2653	722	1	j	j	PROPN
dpc-2653	722	2	am	be	AUX
dpc-2653	722	3	acad	acad	ADJ
dpc-2653	722	4	dermatol	dermatol	NOUN
dpc-2653	722	5	.	.	PUNCT
dpc-2653	723	1	2002	2002	NUM
dpc-2653	723	2	;	;	PUNCT
dpc-2653	724	1	47(4):632–3	47(4):632–3	NUM
dpc-2653	724	2	.	.	NOUN
dpc-2653	724	3	76	76	NUM
dpc-2653	724	4	.	.	PUNCT
dpc-2653	725	1	nakano	nakano	PROPN
dpc-2653	725	2	j	j	PROPN
dpc-2653	725	3	,	,	PUNCT
dpc-2653	725	4	nakamura	nakamura	PROPN
dpc-2653	725	5	m.	m.	PROPN
dpc-2653	725	6	paronychia	paronychia	PROPN
dpc-2653	725	7	induced	induce	VERB
dpc-2653	725	8	by	by	ADP
dpc-2653	725	9	gefitinib	gefitinib	NOUN
dpc-2653	725	10	,	,	PUNCT
dpc-2653	725	11	an	an	DET
dpc-2653	725	12	epidermal	epidermal	ADJ
dpc-2653	725	13	growth	growth	NOUN
dpc-2653	725	14	factor	factor	NOUN
dpc-2653	725	15	receptor	receptor	NOUN
dpc-2653	725	16	tyrosine	tyrosine	PROPN
dpc-2653	725	17	kinase	kinase	PROPN
dpc-2653	725	18	inhibitor	inhibitor	NOUN
dpc-2653	726	1	[	[	X
dpc-2653	726	2	5	5	NUM
dpc-2653	726	3	]	]	PUNCT
dpc-2653	726	4	.	.	PUNCT
dpc-2653	727	1	j	j	NOUN
dpc-2653	727	2	 	 	SPACE
dpc-2653	727	3	dermatol	dermatol	NOUN
dpc-2653	727	4	.	.	PUNCT
dpc-2653	728	1	2003;30(3):261–2	2003;30(3):261–2	NUM
dpc-2653	728	2	.	.	PUNCT
dpc-2653	729	1	77	77	NUM
dpc-2653	729	2	.	.	PUNCT
dpc-2653	730	1	huang	huang	PROPN
dpc-2653	730	2	kl	kl	PROPN
dpc-2653	730	3	,	,	PUNCT
dpc-2653	730	4	lin	lin	PROPN
dpc-2653	730	5	ky	ky	PROPN
dpc-2653	730	6	,	,	PUNCT
dpc-2653	730	7	huang	huang	PROPN
dpc-2653	730	8	tw	tw	PROPN
dpc-2653	730	9	,	,	PUNCT
dpc-2653	730	10	loh	loh	PROPN
dpc-2653	730	11	ew	ew	PROPN
dpc-2653	730	12	,	,	PUNCT
dpc-2653	730	13	hua	hua	PROPN
dpc-2653	730	14	ym	ym	PROPN
dpc-2653	730	15	,	,	PUNCT
dpc-2653	730	16	su	su	PROPN
dpc-2653	730	17	hc	hc	PROPN
dpc-2653	730	18	,	,	PUNCT
dpc-2653	730	19	et	et	PROPN
dpc-2653	730	20	 	 	SPACE
dpc-2653	730	21	al	al	PROPN
dpc-2653	730	22	.	.	PROPN
dpc-2653	730	23	prophylactic	prophylactic	ADJ
dpc-2653	730	24	management	management	NOUN
dpc-2653	730	25	for	for	ADP
dpc-2653	730	26	taxane	taxane	NOUN
dpc-2653	730	27	-	-	PUNCT
dpc-2653	730	28	induced	induce	VERB
dpc-2653	730	29	nail	nail	NOUN
dpc-2653	730	30	toxicity	toxicity	NOUN
dpc-2653	730	31	:	:	PUNCT
dpc-2653	730	32	a	a	DET
dpc-2653	730	33	systematic	systematic	ADJ
dpc-2653	730	34	review	review	NOUN
dpc-2653	730	35	and	and	CCONJ
dpc-2653	730	36	meta	meta	ADJ
dpc-2653	730	37	-	-	PUNCT
dpc-2653	730	38	analysis	analysis	NOUN
dpc-2653	730	39	.	.	PUNCT
dpc-2653	731	1	eur	eur	PROPN
dpc-2653	731	2	j	j	PROPN
dpc-2653	731	3	cancer	cancer	NOUN
dpc-2653	731	4	care	care	NOUN
dpc-2653	731	5	(	(	PUNCT
dpc-2653	731	6	engl	engl	ADJ
dpc-2653	731	7	)	)	PUNCT
dpc-2653	731	8	.	.	PUNCT
dpc-2653	732	1	2019;28(5):1–10	2019;28(5):1–10	NOUN
dpc-2653	732	2	.	.	PUNCT
dpc-2653	733	1	78	78	NUM
dpc-2653	733	2	.	.	PUNCT
dpc-2653	734	1	chanez	chanez	PROPN
dpc-2653	734	2	j	j	PROPN
dpc-2653	734	3	-	-	PROPN
dpc-2653	734	4	f.	f.	PROPN
dpc-2653	734	5	the	the	DET
dpc-2653	734	6	neurogenic	neurogenic	ADJ
dpc-2653	734	7	component	component	NOUN
dpc-2653	734	8	of	of	ADP
dpc-2653	734	9	cutaneous	cutaneous	ADJ
dpc-2653	734	10	toxicities	toxicity	NOUN
dpc-2653	734	11	induced	induce	VERB
dpc-2653	734	12	by	by	ADP
dpc-2653	734	13	chemotherapy	chemotherapy	NOUN
dpc-2653	734	14	—	—	PUNCT
dpc-2653	734	15	new	new	ADJ
dpc-2653	734	16	solutions	solution	NOUN
dpc-2653	734	17	.	.	PUNCT
dpc-2653	735	1	oncol	oncol	ADJ
dpc-2653	735	2	hematol	hematol	NOUN
dpc-2653	735	3	rev	rev	X
dpc-2653	735	4	.	.	PROPN
dpc-2653	736	1	2010;06:17	2010;06:17	NUM
dpc-2653	736	2	.	.	PUNCT
dpc-2653	737	1	79	79	NUM
dpc-2653	737	2	.	.	PUNCT
dpc-2653	738	1	dawid	dawid	VERB
dpc-2653	738	2	-	-	PUNCT
dpc-2653	738	3	pać	pać	PROPN
dpc-2653	738	4	r.	r.	PROPN
dpc-2653	738	5	medicinal	medicinal	PROPN
dpc-2653	738	6	plants	plant	NOUN
dpc-2653	738	7	used	use	VERB
dpc-2653	738	8	in	in	ADP
dpc-2653	738	9	treatment	treatment	NOUN
dpc-2653	738	10	of	of	ADP
dpc-2653	738	11	inflammatory	inflammatory	ADJ
dpc-2653	738	12	skin	skin	NOUN
dpc-2653	738	13	diseases	disease	NOUN
dpc-2653	738	14	.	.	PUNCT
dpc-2653	739	1	postep	postep	NOUN
dpc-2653	739	2	dermatologii	dermatologii	NOUN
dpc-2653	739	3	i	i	PRON
dpc-2653	739	4	alergol	alergol	VERB
dpc-2653	739	5	.	.	PUNCT
dpc-2653	740	1	2013;30(3):170–7	2013;30(3):170–7	NUM
dpc-2653	740	2	.	.	PUNCT
dpc-2653	741	1	80	80	NUM
dpc-2653	741	2	.	.	PUNCT
dpc-2653	742	1	man	man	PROPN
dpc-2653	742	2	mq	mq	PROPN
dpc-2653	742	3	,	,	PUNCT
dpc-2653	742	4	hupe	hupe	NOUN
dpc-2653	742	5	m	m	PROPN
dpc-2653	742	6	,	,	PUNCT
dpc-2653	742	7	sun	sun	NOUN
dpc-2653	742	8	r	r	NOUN
dpc-2653	742	9	,	,	PUNCT
dpc-2653	742	10	man	man	NOUN
dpc-2653	742	11	g	g	NOUN
dpc-2653	742	12	,	,	PUNCT
dpc-2653	742	13	mauro	mauro	PROPN
dpc-2653	742	14	tm	tm	PROPN
dpc-2653	742	15	,	,	PUNCT
dpc-2653	742	16	elias	elias	PROPN
dpc-2653	742	17	pm	pm	PROPN
dpc-2653	742	18	.	.	PUNCT
dpc-2653	743	1	topical	topical	ADJ
dpc-2653	743	2	apigenin	apigenin	PROPN
dpc-2653	743	3	alleviates	alleviate	VERB
dpc-2653	743	4	cutaneous	cutaneous	ADJ
dpc-2653	743	5	inflammation	inflammation	NOUN
dpc-2653	743	6	in	in	ADP
dpc-2653	743	7	murine	murine	ADJ
dpc-2653	743	8	models	model	NOUN
dpc-2653	743	9	.	.	PUNCT
dpc-2653	744	1	evidence	evidence	NOUN
dpc-2653	744	2	-	-	PUNCT
dpc-2653	744	3	based	base	VERB
dpc-2653	744	4	complement	complement	NOUN
dpc-2653	744	5	altern	altern	NOUN
dpc-2653	744	6	med	med	PROPN
dpc-2653	744	7	.	.	PUNCT
dpc-2653	745	1	2012;2012	2012;2012	X
dpc-2653	745	2	.	.	PROPN
dpc-2653	745	3	81	81	NUM
dpc-2653	745	4	.	.	PUNCT
dpc-2653	745	5	wollina	wollina	PROPN
dpc-2653	745	6	u	u	PROPN
dpc-2653	745	7	,	,	PUNCT
dpc-2653	745	8	abdel	abdel	PROPN
dpc-2653	745	9	-	-	PUNCT
dpc-2653	745	10	naser	naser	PROPN
dpc-2653	745	11	mb	mb	PROPN
dpc-2653	745	12	.	.	PROPN
dpc-2653	745	13	drug	drug	NOUN
dpc-2653	745	14	reactions	reaction	NOUN
dpc-2653	745	15	affecting	affect	VERB
dpc-2653	745	16	hair	hair	NOUN
dpc-2653	745	17	and	and	CCONJ
dpc-2653	745	18	nails	nail	NOUN
dpc-2653	745	19	.	.	PUNCT
dpc-2653	746	1	clin	clin	PROPN
dpc-2653	746	2	dermatol	dermatol	NOUN
dpc-2653	747	1	[	[	X
dpc-2653	747	2	internet	internet	NOUN
dpc-2653	747	3	]	]	PUNCT
dpc-2653	747	4	.	.	PUNCT
dpc-2653	748	1	2020;38(6):693–701	2020;38(6):693–701	X
dpc-2653	748	2	.	.	PROPN
dpc-2653	748	3	available	available	ADJ
dpc-2653	748	4	from	from	ADP
dpc-2653	748	5	:	:	PUNCT
dpc-2653	748	6	https://doi.org/10.1016/j.clindermatol.2020.06.009	https://doi.org/10.1016/j.clindermatol.2020.06.009	NOUN