id	sid	tid	token	lemma	pos
dpc-3558	1	1	dermatology	dermatology	NOUN
dpc-3558	1	2	:	:	PUNCT
dpc-3558	1	3	practical	practical	ADJ
dpc-3558	1	4	and	and	CCONJ
dpc-3558	1	5	conceptual	conceptual	ADJ
dpc-3558	1	6	original	original	ADJ
dpc-3558	1	7	article	article	NOUN
dpc-3558	1	8	|	|	ADV
dpc-3558	1	9	dermatol	dermatol	ADJ
dpc-3558	1	10	pract	pract	NOUN
dpc-3558	1	11	concept	concept	NOUN
dpc-3558	1	12	.	.	PUNCT
dpc-3558	2	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	2	2	1	1	NUM
dpc-3558	2	3	familial	familial	ADJ
dpc-3558	2	4	melanoma	melanoma	NOUN
dpc-3558	2	5	phenotype	phenotype	NOUN
dpc-3558	2	6	with	with	ADP
dpc-3558	2	7	xeroderma	xeroderma	PROPN
dpc-3558	2	8	pigmentosum	pigmentosum	PROPN
dpc-3558	2	9	group	group	PROPN
dpc-3558	2	10	c	c	PROPN
dpc-3558	2	11	(	(	PUNCT
dpc-3558	2	12	xp	xp	PROPN
dpc-3558	2	13	-	-	PUNCT
dpc-3558	2	14	c	c	NOUN
dpc-3558	2	15	)	)	PUNCT
dpc-3558	2	16	genotype	genotype	NOUN
dpc-3558	2	17	the	the	DET
dpc-3558	2	18	putative	putative	ADJ
dpc-3558	2	19	role	role	NOUN
dpc-3558	2	20	of	of	ADP
dpc-3558	2	21	mc1r	mc1r	PROPN
dpc-3558	2	22	polymorphism	polymorphism	NOUN
dpc-3558	2	23	as	as	ADP
dpc-3558	2	24	modifier	modifier	NOUN
dpc-3558	2	25	franciele	franciele	PROPN
dpc-3558	2	26	antonieta	antonieta	PROPN
dpc-3558	2	27	bianchi	bianchi	PROPN
dpc-3558	2	28	leidenz1	leidenz1	PROPN
dpc-3558	2	29	,	,	PUNCT
dpc-3558	2	30	flavia	flavia	PROPN
dpc-3558	2	31	vasques	vasques	PROPN
dpc-3558	2	32	bittencourt2	bittencourt2	PROPN
dpc-3558	2	33	,	,	PUNCT
dpc-3558	2	34	williana	williana	PROPN
dpc-3558	2	35	garcia	garcia	PROPN
dpc-3558	2	36	braga1	braga1	PROPN
dpc-3558	2	37	,	,	PUNCT
dpc-3558	2	38	elio	elio	PROPN
dpc-3558	2	39	magno	magno	PROPN
dpc-3558	2	40	de	de	PROPN
dpc-3558	2	41	sá	sá	PROPN
dpc-3558	2	42	araújo1	araújo1	PROPN
dpc-3558	2	43	,	,	PUNCT
dpc-3558	2	44	carolina	carolina	PROPN
dpc-3558	2	45	cavalieri	cavalieri	PROPN
dpc-3558	2	46	gomes3	gomes3	PROPN
dpc-3558	2	47	,	,	PUNCT
dpc-3558	2	48	vanessa	vanessa	PROPN
dpc-3558	2	49	de	de	PROPN
dpc-3558	2	50	fatima	fatima	PROPN
dpc-3558	2	51	bernardes3	bernardes3	PROPN
dpc-3558	2	52	,	,	PUNCT
dpc-3558	2	53	eitan	eitan	PROPN
dpc-3558	2	54	friedman4	friedman4	PROPN
dpc-3558	2	55	,	,	PUNCT
dpc-3558	2	56	luiz	luiz	PROPN
dpc-3558	2	57	de	de	ADP
dpc-3558	2	58	marco1	marco1	X
dpc-3558	2	59	1	1	NUM
dpc-3558	2	60	departments	department	NOUN
dpc-3558	2	61	of	of	ADP
dpc-3558	2	62	surgery	surgery	NOUN
dpc-3558	2	63	,	,	PUNCT
dpc-3558	2	64	school	school	NOUN
dpc-3558	2	65	of	of	ADP
dpc-3558	2	66	medicine	medicine	NOUN
dpc-3558	2	67	,	,	PUNCT
dpc-3558	2	68	universidade	universidade	PROPN
dpc-3558	2	69	federal	federal	PROPN
dpc-3558	2	70	de	de	PROPN
dpc-3558	2	71	minas	minas	PROPN
dpc-3558	2	72	gerais	gerais	PROPN
dpc-3558	2	73	,	,	PUNCT
dpc-3558	2	74	belo	belo	PROPN
dpc-3558	2	75	horizonte	horizonte	PROPN
dpc-3558	2	76	,	,	PUNCT
dpc-3558	2	77	brazil	brazil	PROPN
dpc-3558	2	78	2	2	NUM
dpc-3558	2	79	departments	department	NOUN
dpc-3558	2	80	of	of	ADP
dpc-3558	2	81	medicine	medicine	NOUN
dpc-3558	2	82	,	,	PUNCT
dpc-3558	2	83	school	school	NOUN
dpc-3558	2	84	of	of	ADP
dpc-3558	2	85	medicine	medicine	NOUN
dpc-3558	2	86	,	,	PUNCT
dpc-3558	2	87	universidade	universidade	PROPN
dpc-3558	2	88	federal	federal	PROPN
dpc-3558	2	89	de	de	PROPN
dpc-3558	2	90	minas	minas	PROPN
dpc-3558	2	91	gerais	gerais	PROPN
dpc-3558	2	92	,	,	PUNCT
dpc-3558	2	93	belo	belo	PROPN
dpc-3558	2	94	horizonte	horizonte	PROPN
dpc-3558	2	95	,	,	PUNCT
dpc-3558	2	96	brazil	brazil	PROPN
dpc-3558	2	97	3	3	NUM
dpc-3558	2	98	departments	department	NOUN
dpc-3558	2	99	of	of	ADP
dpc-3558	2	100	pathology	pathology	NOUN
dpc-3558	2	101	,	,	PUNCT
dpc-3558	2	102	school	school	NOUN
dpc-3558	2	103	of	of	ADP
dpc-3558	2	104	medicine	medicine	NOUN
dpc-3558	2	105	,	,	PUNCT
dpc-3558	2	106	universidade	universidade	PROPN
dpc-3558	2	107	federal	federal	PROPN
dpc-3558	2	108	de	de	PROPN
dpc-3558	2	109	minas	minas	PROPN
dpc-3558	2	110	gerais	gerais	PROPN
dpc-3558	2	111	,	,	PUNCT
dpc-3558	2	112	belo	belo	PROPN
dpc-3558	2	113	horizonte	horizonte	PROPN
dpc-3558	2	114	,	,	PUNCT
dpc-3558	2	115	brazil	brazil	PROPN
dpc-3558	2	116	4	4	NUM
dpc-3558	2	117	the	the	DET
dpc-3558	2	118	preventive	preventive	ADJ
dpc-3558	2	119	personalized	personalized	ADJ
dpc-3558	2	120	medicine	medicine	NOUN
dpc-3558	2	121	center	center	NOUN
dpc-3558	2	122	,	,	PUNCT
dpc-3558	2	123	assuta	assuta	PROPN
dpc-3558	2	124	medical	medical	ADJ
dpc-3558	2	125	center	center	NOUN
dpc-3558	2	126	and	and	CCONJ
dpc-3558	2	127	the	the	DET
dpc-3558	2	128	sackler	sackler	ADJ
dpc-3558	2	129	school	school	NOUN
dpc-3558	2	130	of	of	ADP
dpc-3558	2	131	medicine	medicine	NOUN
dpc-3558	2	132	,	,	PUNCT
dpc-3558	2	133	tel	tel	PROPN
dpc-3558	2	134	-	-	PUNCT
dpc-3558	2	135	aviv	aviv	PROPN
dpc-3558	2	136	university	university	PROPN
dpc-3558	2	137	,	,	PUNCT
dpc-3558	2	138	tel	tel	PROPN
dpc-3558	2	139	-	-	PUNCT
dpc-3558	2	140	aviv	aviv	PROPN
dpc-3558	2	141	,	,	PUNCT
dpc-3558	2	142	israel	israel	PROPN
dpc-3558	2	143	key	key	ADJ
dpc-3558	2	144	words	word	NOUN
dpc-3558	2	145	:	:	PUNCT
dpc-3558	2	146	xeroderma	xeroderma	PROPN
dpc-3558	2	147	pigmentosum	pigmentosum	PROPN
dpc-3558	2	148	,	,	PUNCT
dpc-3558	2	149	familial	familial	ADJ
dpc-3558	2	150	melanoma	melanoma	NOUN
dpc-3558	2	151	,	,	PUNCT
dpc-3558	2	152	xpc	xpc	PROPN
dpc-3558	2	153	,	,	PUNCT
dpc-3558	2	154	mc1r	mc1r	PROPN
dpc-3558	2	155	,	,	PUNCT
dpc-3558	2	156	modifier	modifier	NOUN
dpc-3558	2	157	genes	gene	NOUN
dpc-3558	2	158	citation	citation	NOUN
dpc-3558	2	159	:	:	PUNCT
dpc-3558	2	160	leidenz	leidenz	PROPN
dpc-3558	2	161	fa	fa	PROPN
dpc-3558	2	162	,	,	PUNCT
dpc-3558	2	163	bittencourt	bittencourt	PROPN
dpc-3558	2	164	fv	fv	PROPN
dpc-3558	2	165	,	,	PUNCT
dpc-3558	2	166	braga	braga	NOUN
dpc-3558	2	167	wg	wg	PROPN
dpc-3558	2	168	,	,	PUNCT
dpc-3558	2	169	et	et	PROPN
dpc-3558	2	170	al	al	PROPN
dpc-3558	2	171	.	.	PUNCT
dpc-3558	3	1	familial	familial	ADJ
dpc-3558	3	2	melanoma	melanoma	NOUN
dpc-3558	3	3	phenotype	phenotype	NOUN
dpc-3558	3	4	with	with	ADP
dpc-3558	3	5	xeroderma	xeroderma	PROPN
dpc-3558	3	6	pigmentosum	pigmentosum	PROPN
dpc-3558	3	7	group	group	PROPN
dpc-3558	3	8	c	c	PROPN
dpc-3558	3	9	(	(	PUNCT
dpc-3558	3	10	xp	xp	PROPN
dpc-3558	3	11	-	-	PUNCT
dpc-3558	3	12	c	c	NOUN
dpc-3558	3	13	)	)	PUNCT
dpc-3558	3	14	genotype	genotype	NOUN
dpc-3558	3	15	the	the	DET
dpc-3558	3	16	putative	putative	ADJ
dpc-3558	3	17	role	role	NOUN
dpc-3558	3	18	of	of	ADP
dpc-3558	3	19	mc1r	mc1r	PROPN
dpc-3558	3	20	polymorphism	polymorphism	NOUN
dpc-3558	3	21	as	as	ADP
dpc-3558	3	22	modifier	modifier	NOUN
dpc-3558	3	23	.	.	PUNCT
dpc-3558	4	1	dermatol	dermatol	NOUN
dpc-3558	4	2	pract	pract	PROPN
dpc-3558	4	3	concept	concept	NOUN
dpc-3558	4	4	.	.	PUNCT
dpc-3558	5	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	5	2	.	.	PUNCT
dpc-3558	6	1	doi	doi	NOUN
dpc-3558	6	2	:	:	PUNCT
dpc-3558	7	1	https://doi	https://doi	PROPN
dpc-3558	7	2	.	.	PUNCT
dpc-3558	7	3	org/10.5826	org/10.5826	NUM
dpc-3558	7	4	/	/	SYM
dpc-3558	7	5	dpc.1401a50	dpc.1401a50	NOUN
dpc-3558	7	6	accepted	accept	VERB
dpc-3558	7	7	:	:	PUNCT
dpc-3558	7	8	september	september	PROPN
dpc-3558	7	9	27	27	NUM
dpc-3558	7	10	,	,	PUNCT
dpc-3558	7	11	2023	2023	NUM
dpc-3558	7	12	;	;	PUNCT
dpc-3558	7	13	published	publish	VERB
dpc-3558	7	14	:	:	PUNCT
dpc-3558	7	15	january	january	PROPN
dpc-3558	7	16	2024	2024	NUM
dpc-3558	8	1	copyright	copyright	NOUN
dpc-3558	8	2	:	:	PUNCT
dpc-3558	8	3	©	©	PROPN
dpc-3558	8	4	2024	2024	NUM
dpc-3558	8	5	leidenz	leidenz	NOUN
dpc-3558	8	6	et	et	PROPN
dpc-3558	8	7	al	al	PROPN
dpc-3558	8	8	.	.	PUNCT
dpc-3558	9	1	this	this	PRON
dpc-3558	9	2	is	be	AUX
dpc-3558	9	3	an	an	DET
dpc-3558	9	4	open	open	ADJ
dpc-3558	9	5	-	-	PUNCT
dpc-3558	9	6	access	access	NOUN
dpc-3558	9	7	article	article	NOUN
dpc-3558	9	8	distributed	distribute	VERB
dpc-3558	9	9	under	under	ADP
dpc-3558	9	10	the	the	DET
dpc-3558	9	11	terms	term	NOUN
dpc-3558	9	12	of	of	ADP
dpc-3558	9	13	the	the	DET
dpc-3558	9	14	creative	creative	ADJ
dpc-3558	9	15	commons	common	NOUN
dpc-3558	9	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-3558	9	17	license	license	NOUN
dpc-3558	9	18	(	(	PUNCT
dpc-3558	9	19	by	by	ADP
dpc-3558	9	20	-	-	PUNCT
dpc-3558	9	21	nc-4.0	nc-4.0	NOUN
dpc-3558	9	22	)	)	PUNCT
dpc-3558	9	23	,	,	PUNCT
dpc-3558	9	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-3558	9	25	,	,	PUNCT
dpc-3558	9	26	which	which	PRON
dpc-3558	9	27	permits	permit	VERB
dpc-3558	9	28	unrestricted	unrestricted	ADJ
dpc-3558	9	29	noncommercial	noncommercial	ADJ
dpc-3558	9	30	use	use	NOUN
dpc-3558	9	31	,	,	PUNCT
dpc-3558	9	32	distribution	distribution	NOUN
dpc-3558	9	33	,	,	PUNCT
dpc-3558	9	34	and	and	CCONJ
dpc-3558	9	35	reproduction	reproduction	NOUN
dpc-3558	9	36	in	in	ADP
dpc-3558	9	37	any	any	DET
dpc-3558	9	38	medium	medium	NOUN
dpc-3558	9	39	,	,	PUNCT
dpc-3558	9	40	provided	provide	VERB
dpc-3558	9	41	the	the	DET
dpc-3558	9	42	original	original	ADJ
dpc-3558	9	43	authors	author	NOUN
dpc-3558	9	44	and	and	CCONJ
dpc-3558	9	45	source	source	NOUN
dpc-3558	9	46	are	be	AUX
dpc-3558	9	47	credited	credit	VERB
dpc-3558	9	48	.	.	PUNCT
dpc-3558	10	1	funding	funding	NOUN
dpc-3558	10	2	:	:	PUNCT
dpc-3558	10	3	this	this	DET
dpc-3558	10	4	work	work	NOUN
dpc-3558	10	5	was	be	AUX
dpc-3558	10	6	partially	partially	ADV
dpc-3558	10	7	funded	fund	VERB
dpc-3558	10	8	by	by	ADP
dpc-3558	10	9	conselho	conselho	NOUN
dpc-3558	10	10	nacional	nacional	PROPN
dpc-3558	10	11	de	de	X
dpc-3558	10	12	desenvolvimento	desenvolvimento	PROPN
dpc-3558	10	13	científico	científico	PROPN
dpc-3558	10	14	e	e	NOUN
dpc-3558	10	15	tecnológico	tecnológico	PROPN
dpc-3558	10	16	(	(	PUNCT
dpc-3558	10	17	cnpq	cnpq	NOUN
dpc-3558	10	18	#	#	NOUN
dpc-3558	10	19	302291/2019	302291/2019	NUM
dpc-3558	10	20	-	-	SYM
dpc-3558	10	21	9	9	NUM
dpc-3558	10	22	)	)	PUNCT
dpc-3558	10	23	,	,	PUNCT
dpc-3558	10	24	capes	cape	NOUN
dpc-3558	10	25	and	and	CCONJ
dpc-3558	10	26	fundação	fundação	PROPN
dpc-3558	10	27	de	de	X
dpc-3558	10	28	amparo	amparo	PROPN
dpc-3558	10	29	à	à	X
dpc-3558	10	30	pesquisa	pesquisa	X
dpc-3558	10	31	de	de	PROPN
dpc-3558	10	32	minas	minas	PROPN
dpc-3558	10	33	gerais	gerais	PROPN
dpc-3558	10	34	(	(	PUNCT
dpc-3558	10	35	fapemig	fapemig	PROPN
dpc-3558	10	36	#	#	NOUN
dpc-3558	10	37	cds	cd	NOUN
dpc-3558	10	38	-	-	PUNCT
dpc-3558	10	39	red-00019	red-00019	NOUN
dpc-3558	10	40	-	-	PUNCT
dpc-3558	10	41	16	16	NUM
dpc-3558	10	42	)	)	PUNCT
dpc-3558	10	43	.	.	PUNCT
dpc-3558	11	1	the	the	DET
dpc-3558	11	2	sponsors	sponsor	NOUN
dpc-3558	11	3	had	have	VERB
dpc-3558	11	4	no	no	DET
dpc-3558	11	5	role	role	NOUN
dpc-3558	11	6	in	in	ADP
dpc-3558	11	7	the	the	DET
dpc-3558	11	8	design	design	NOUN
dpc-3558	11	9	or	or	CCONJ
dpc-3558	11	10	conduct	conduct	NOUN
dpc-3558	11	11	of	of	ADP
dpc-3558	11	12	this	this	DET
dpc-3558	11	13	research	research	NOUN
dpc-3558	11	14	.	.	PUNCT
dpc-3558	12	1	competing	compete	VERB
dpc-3558	12	2	interests	interest	NOUN
dpc-3558	12	3	:	:	PUNCT
dpc-3558	12	4	none	none	NOUN
dpc-3558	12	5	.	.	PUNCT
dpc-3558	13	1	authorship	authorship	NOUN
dpc-3558	13	2	:	:	PUNCT
dpc-3558	13	3	all	all	DET
dpc-3558	13	4	authors	author	NOUN
dpc-3558	13	5	have	have	AUX
dpc-3558	13	6	contributed	contribute	VERB
dpc-3558	13	7	significantly	significantly	ADV
dpc-3558	13	8	to	to	ADP
dpc-3558	13	9	this	this	DET
dpc-3558	13	10	publication	publication	NOUN
dpc-3558	13	11	.	.	PUNCT
dpc-3558	14	1	corresponding	correspond	VERB
dpc-3558	14	2	author	author	NOUN
dpc-3558	14	3	:	:	PUNCT
dpc-3558	14	4	l.	l.	PROPN
dpc-3558	14	5	de	de	PROPN
dpc-3558	14	6	marco	marco	PROPN
dpc-3558	14	7	,	,	PUNCT
dpc-3558	14	8	department	department	NOUN
dpc-3558	14	9	of	of	ADP
dpc-3558	14	10	surgery	surgery	NOUN
dpc-3558	14	11	,	,	PUNCT
dpc-3558	14	12	school	school	NOUN
dpc-3558	14	13	of	of	ADP
dpc-3558	14	14	medicine	medicine	NOUN
dpc-3558	14	15	,	,	PUNCT
dpc-3558	14	16	universidade	universidade	PROPN
dpc-3558	14	17	federal	federal	PROPN
dpc-3558	14	18	de	de	PROPN
dpc-3558	14	19	minas	minas	PROPN
dpc-3558	14	20	gerais	gerais	PROPN
dpc-3558	14	21	,	,	PUNCT
dpc-3558	14	22	av	av	PROPN
dpc-3558	14	23	alfredo	alfredo	NOUN
dpc-3558	14	24	balena	balena	PROPN
dpc-3558	14	25	190	190	NUM
dpc-3558	14	26	,	,	PUNCT
dpc-3558	14	27	belo	belo	VERB
dpc-3558	14	28	horizonte	horizonte	ADV
dpc-3558	14	29	30130	30130	NUM
dpc-3558	14	30	-	-	SYM
dpc-3558	14	31	100	100	NUM
dpc-3558	14	32	,	,	PUNCT
dpc-3558	14	33	brazil	brazil	PROPN
dpc-3558	14	34	;	;	PUNCT
dpc-3558	14	35	e	e	X
dpc-3558	14	36	-	-	NOUN
dpc-3558	14	37	mail	mail	NOUN
dpc-3558	14	38	:	:	PUNCT
dpc-3558	14	39	ldemarco@ufmg.br	ldemarco@ufmg.br	NOUN
dpc-3558	14	40	.	.	PUNCT
dpc-3558	15	1	introduction	introduction	NOUN
dpc-3558	15	2	:	:	PUNCT
dpc-3558	15	3	xeroderma	xeroderma	PROPN
dpc-3558	15	4	pigmentosum	pigmentosum	PROPN
dpc-3558	15	5	(	(	PUNCT
dpc-3558	15	6	xp	xp	INTJ
dpc-3558	15	7	)	)	PUNCT
dpc-3558	15	8	,	,	PUNCT
dpc-3558	15	9	a	a	DET
dpc-3558	15	10	rare	rare	ADJ
dpc-3558	15	11	inherited	inherit	VERB
dpc-3558	15	12	condition	condition	NOUN
dpc-3558	15	13	,	,	PUNCT
dpc-3558	15	14	hallmarked	hallmarke	VERB
dpc-3558	15	15	by	by	ADP
dpc-3558	15	16	extreme	extreme	ADJ
dpc-3558	15	17	sensitivity	sensitivity	NOUN
dpc-3558	15	18	to	to	ADP
dpc-3558	15	19	sun	sun	NOUN
dpc-3558	15	20	exposure	exposure	NOUN
dpc-3558	15	21	resulting	result	VERB
dpc-3558	15	22	in	in	ADP
dpc-3558	15	23	multiple	multiple	ADJ
dpc-3558	15	24	skin	skin	NOUN
dpc-3558	15	25	cancers	cancer	NOUN
dpc-3558	15	26	and	and	CCONJ
dpc-3558	15	27	non	non	ADJ
dpc-3558	15	28	-	-	ADJ
dpc-3558	15	29	malignant	malignant	ADJ
dpc-3558	15	30	skin	skin	NOUN
dpc-3558	15	31	alterations	alteration	NOUN
dpc-3558	15	32	is	be	AUX
dpc-3558	15	33	attributed	attribute	VERB
dpc-3558	15	34	to	to	ADP
dpc-3558	15	35	homozygous	homozygous	ADJ
dpc-3558	15	36	inactivating	inactivating	ADJ
dpc-3558	15	37	pathogenic	pathogenic	ADJ
dpc-3558	15	38	variants	variant	NOUN
dpc-3558	15	39	(	(	PUNCT
dpc-3558	15	40	pvs	pvs	PROPN
dpc-3558	15	41	)	)	PUNCT
dpc-3558	15	42	in	in	ADP
dpc-3558	15	43	dna	dna	PROPN
dpc-3558	15	44	repair	repair	NOUN
dpc-3558	15	45	genes	gene	NOUN
dpc-3558	15	46	,	,	PUNCT
dpc-3558	15	47	predominantly	predominantly	ADV
dpc-3558	15	48	the	the	DET
dpc-3558	15	49	xpc	xpc	PROPN
dpc-3558	15	50	gene	gene	NOUN
dpc-3558	15	51	.	.	PUNCT
dpc-3558	16	1	objectives	objective	NOUN
dpc-3558	16	2	:	:	PUNCT
dpc-3558	16	3	report	report	VERB
dpc-3558	16	4	a	a	DET
dpc-3558	16	5	unique	unique	ADJ
dpc-3558	16	6	phenotypic	phenotypic	ADJ
dpc-3558	16	7	expression	expression	NOUN
dpc-3558	16	8	of	of	ADP
dpc-3558	16	9	mutant	mutant	ADJ
dpc-3558	16	10	xpc	xpc	PROPN
dpc-3558	16	11	allele	allele	NOUN
dpc-3558	16	12	that	that	PRON
dpc-3558	16	13	may	may	AUX
dpc-3558	16	14	be	be	AUX
dpc-3558	16	15	compatible	compatible	ADJ
dpc-3558	16	16	with	with	ADP
dpc-3558	16	17	a	a	DET
dpc-3558	16	18	putative	putative	ADJ
dpc-3558	16	19	modifier	modifier	NOUN
dpc-3558	16	20	role	role	NOUN
dpc-3558	16	21	for	for	ADP
dpc-3558	16	22	mc1r	mc1r	PROPN
dpc-3558	16	23	polymorphism	polymorphism	NOUN
dpc-3558	16	24	.	.	PUNCT
dpc-3558	17	1	methods	method	NOUN
dpc-3558	17	2	:	:	PUNCT
dpc-3558	17	3	a	a	DET
dpc-3558	17	4	family	family	NOUN
dpc-3558	17	5	of	of	ADP
dpc-3558	17	6	13	13	NUM
dpc-3558	17	7	siblings	sibling	NOUN
dpc-3558	17	8	,	,	PUNCT
dpc-3558	17	9	seven	seven	NUM
dpc-3558	17	10	of	of	ADP
dpc-3558	17	11	whom	whom	PRON
dpc-3558	17	12	were	be	AUX
dpc-3558	17	13	diagnosed	diagnose	VERB
dpc-3558	17	14	with	with	ADP
dpc-3558	17	15	at	at	ADV
dpc-3558	17	16	least	least	ADV
dpc-3558	17	17	one	one	NUM
dpc-3558	17	18	cutaneous	cutaneous	ADJ
dpc-3558	17	19	melanoma	melanoma	NOUN
dpc-3558	17	20	(	(	PUNCT
dpc-3558	17	21	n	n	NOUN
dpc-3558	17	22	=	=	SYM
dpc-3558	17	23	53	53	NUM
dpc-3558	17	24	)	)	PUNCT
dpc-3558	17	25	and	and	CCONJ
dpc-3558	17	26	non	non	ADJ
dpc-3558	17	27	-	-	ADJ
dpc-3558	17	28	melanoma	melanoma	ADJ
dpc-3558	17	29	skin	skin	NOUN
dpc-3558	17	30	cancers	cancer	NOUN
dpc-3558	17	31	(	(	PUNCT
dpc-3558	17	32	n	n	NOUN
dpc-3558	17	33	=	=	SYM
dpc-3558	17	34	9	9	NUM
dpc-3558	17	35	)	)	PUNCT
dpc-3558	17	36	was	be	AUX
dpc-3558	17	37	studied	study	VERB
dpc-3558	17	38	.	.	PUNCT
dpc-3558	18	1	of	of	ADP
dpc-3558	18	2	seven	seven	NUM
dpc-3558	18	3	melanoma	melanoma	NOUN
dpc-3558	18	4	-	-	PUNCT
dpc-3558	18	5	affected	affect	VERB
dpc-3558	18	6	cases	case	NOUN
dpc-3558	18	7	,	,	PUNCT
dpc-3558	18	8	five	five	NUM
dpc-3558	18	9	consented	consent	VERB
dpc-3558	18	10	for	for	ADP
dpc-3558	18	11	genetic	genetic	ADJ
dpc-3558	18	12	analysis	analysis	NOUN
dpc-3558	18	13	.	.	PUNCT
dpc-3558	19	1	cdkn2a	cdkn2a	PROPN
dpc-3558	19	2	revealed	reveal	VERB
dpc-3558	19	3	no	no	INTJ
dpc-3558	19	4	pv	pv	NOUN
dpc-3558	19	5	in	in	ADP
dpc-3558	19	6	any	any	DET
dpc-3558	19	7	case	case	NOUN
dpc-3558	19	8	and	and	CCONJ
dpc-3558	19	9	subsequent	subsequent	ADJ
dpc-3558	19	10	whole	whole	ADJ
dpc-3558	19	11	-	-	PUNCT
dpc-3558	19	12	exome	exome	NOUN
dpc-3558	19	13	sequencing	sequencing	NOUN
dpc-3558	19	14	(	(	PUNCT
dpc-3558	19	15	wes	wes	PROPN
dpc-3558	19	16	)	)	PUNCT
dpc-3558	19	17	identified	identify	VERB
dpc-3558	19	18	a	a	DET
dpc-3558	19	19	rare	rare	ADJ
dpc-3558	19	20	homozygous	homozygous	ADJ
dpc-3558	19	21	missense	missense	NOUN
dpc-3558	19	22	pv	pv	NOUN
dpc-3558	19	23	(	(	PUNCT
dpc-3558	19	24	c.919c	c.919c	PROPN
dpc-3558	19	25	>	>	X
dpc-3558	19	26	t	t	PROPN
dpc-3558	19	27	;	;	PUNCT
dpc-3558	19	28	p.arg307trp	p.arg307trp	PROPN
dpc-3558	19	29	)	)	PUNCT
dpc-3558	19	30	in	in	ADP
dpc-3558	19	31	exon	exon	NOUN
dpc-3558	19	32	8	8	NUM
dpc-3558	19	33	of	of	ADP
dpc-3558	19	34	the	the	DET
dpc-3558	19	35	xpc	xpc	PROPN
dpc-3558	19	36	gene	gene	NOUN
dpc-3558	19	37	in	in	ADP
dpc-3558	19	38	all	all	DET
dpc-3558	19	39	affected	affected	ADJ
dpc-3558	19	40	individuals	individual	NOUN
dpc-3558	19	41	.	.	PUNCT
dpc-3558	20	1	notably	notably	ADV
dpc-3558	20	2	,	,	PUNCT
dpc-3558	20	3	xpc	xpc	PROPN
dpc-3558	20	4	pv	pv	NOUN
dpc-3558	20	5	carriers	carrier	NOUN
dpc-3558	20	6	who	who	PRON
dpc-3558	20	7	co	co	VERB
dpc-3558	20	8	-	-	VERB
dpc-3558	20	9	harbored	harbor	VERB
dpc-3558	20	10	the	the	DET
dpc-3558	20	11	p.i155	p.i155	PROPN
dpc-3558	20	12	t	t	PROPN
dpc-3558	20	13	mc1r	mc1r	PROPN
dpc-3558	20	14	variant	variant	NOUN
dpc-3558	20	15	(	(	PUNCT
dpc-3558	20	16	n	n	NOUN
dpc-3558	20	17	=	=	SYM
dpc-3558	20	18	3	3	NUM
dpc-3558	20	19	)	)	PUNCT
dpc-3558	20	20	exhibited	exhibit	VERB
dpc-3558	20	21	larger	large	ADJ
dpc-3558	20	22	number	number	NOUN
dpc-3558	20	23	of	of	ADP
dpc-3558	20	24	tumors	tumor	NOUN
dpc-3558	20	25	,	,	PUNCT
dpc-3558	20	26	deeper	deep	ADJ
dpc-3558	20	27	breslow	breslow	ADJ
dpc-3558	20	28	indexes	index	NOUN
dpc-3558	20	29	,	,	PUNCT
dpc-3558	20	30	higher	high	ADJ
dpc-3558	20	31	rates	rate	NOUN
dpc-3558	20	32	of	of	ADP
dpc-3558	20	33	invasive	invasive	ADJ
dpc-3558	20	34	melanomas	melanoma	NOUN
dpc-3558	20	35	and	and	CCONJ
dpc-3558	20	36	earlier	early	ADJ
dpc-3558	20	37	age	age	NOUN
dpc-3558	20	38	at	at	ADP
dpc-3558	20	39	diagnosis	diagnosis	NOUN
dpc-3558	20	40	compared	compare	VERB
dpc-3558	20	41	with	with	ADP
dpc-3558	20	42	non	non	ADJ
dpc-3558	20	43	mc1r	mc1r	PROPN
dpc-3558	20	44	variant	variant	ADJ
dpc-3558	20	45	carriers	carrier	NOUN
dpc-3558	20	46	(	(	PUNCT
dpc-3558	20	47	n	n	NOUN
dpc-3558	20	48	=	=	SYM
dpc-3558	20	49	2	2	NUM
dpc-3558	20	50	)	)	PUNCT
dpc-3558	20	51	.	.	PUNCT
dpc-3558	21	1	conclusions	conclusion	NOUN
dpc-3558	21	2	:	:	PUNCT
dpc-3558	21	3	familial	familial	ADJ
dpc-3558	21	4	malignant	malignant	ADJ
dpc-3558	21	5	melanoma	melanoma	NOUN
dpc-3558	21	6	phenotype	phenotype	NOUN
dpc-3558	21	7	may	may	AUX
dpc-3558	21	8	,	,	PUNCT
dpc-3558	21	9	in	in	ADP
dpc-3558	21	10	fact	fact	NOUN
dpc-3558	21	11	,	,	PUNCT
dpc-3558	21	12	be	be	AUX
dpc-3558	21	13	an	an	DET
dpc-3558	21	14	unusual	unusual	ADJ
dpc-3558	21	15	clinical	clinical	ADJ
dpc-3558	21	16	presentation	presentation	NOUN
dpc-3558	21	17	of	of	ADP
dpc-3558	21	18	xpc	xpc	PROPN
dpc-3558	21	19	,	,	PUNCT
dpc-3558	21	20	and	and	CCONJ
dpc-3558	21	21	mc1r	mc1r	PROPN
dpc-3558	21	22	may	may	AUX
dpc-3558	21	23	be	be	AUX
dpc-3558	21	24	a	a	DET
dpc-3558	21	25	genetic	genetic	ADJ
dpc-3558	21	26	modifier	modifier	NOUN
dpc-3558	21	27	of	of	ADP
dpc-3558	21	28	penetrance	penetrance	NOUN
dpc-3558	21	29	and	and	CCONJ
dpc-3558	21	30	phenotype	phenotype	NOUN
dpc-3558	21	31	of	of	ADP
dpc-3558	21	32	mutant	mutant	ADJ
dpc-3558	21	33	xpc	xpc	PROPN
dpc-3558	21	34	alleles	allele	NOUN
dpc-3558	21	35	.	.	PUNCT
dpc-3558	22	1	abstract	abstract	ADJ
dpc-3558	22	2	2	2	NUM
dpc-3558	22	3	original	original	ADJ
dpc-3558	22	4	article	article	NOUN
dpc-3558	22	5	|	|	ADV
dpc-3558	22	6	dermatol	dermatol	ADJ
dpc-3558	22	7	pract	pract	NOUN
dpc-3558	22	8	concept	concept	NOUN
dpc-3558	22	9	.	.	PUNCT
dpc-3558	23	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	23	2	introduction	introduction	NOUN
dpc-3558	23	3	xeroderma	xeroderma	PROPN
dpc-3558	23	4	pigmentosum	pigmentosum	PROPN
dpc-3558	23	5	(	(	PUNCT
dpc-3558	23	6	xp	xp	INTJ
dpc-3558	23	7	)	)	PUNCT
dpc-3558	23	8	is	be	AUX
dpc-3558	23	9	a	a	DET
dpc-3558	23	10	rare	rare	ADJ
dpc-3558	23	11	autosomal	autosomal	ADJ
dpc-3558	23	12	recessive	recessive	ADJ
dpc-3558	23	13	disorder	disorder	NOUN
dpc-3558	23	14	whose	whose	DET
dpc-3558	23	15	estimated	estimate	VERB
dpc-3558	23	16	rates	rate	NOUN
dpc-3558	23	17	of	of	ADP
dpc-3558	23	18	2.3/1,000,000	2.3/1,000,000	NUM
dpc-3558	23	19	in	in	ADP
dpc-3558	23	20	western	western	ADJ
dpc-3558	23	21	countries	country	NOUN
dpc-3558	23	22	clinically	clinically	ADV
dpc-3558	23	23	hallmarked	hallmarke	VERB
dpc-3558	23	24	by	by	ADP
dpc-3558	23	25	multitude	multitude	NOUN
dpc-3558	23	26	of	of	ADP
dpc-3558	23	27	skin	skin	NOUN
dpc-3558	23	28	anomalies	anomaly	NOUN
dpc-3558	23	29	[	[	X
dpc-3558	23	30	1	1	NUM
dpc-3558	23	31	]	]	NOUN
dpc-3558	23	32	:	:	PUNCT
dpc-3558	23	33	hyperpigmentation	hyperpigmentation	NOUN
dpc-3558	23	34	,	,	PUNCT
dpc-3558	23	35	premature	premature	ADJ
dpc-3558	23	36	skin	skin	NOUN
dpc-3558	23	37	aging	aging	NOUN
dpc-3558	23	38	,	,	PUNCT
dpc-3558	23	39	cutaneous	cutaneous	ADJ
dpc-3558	23	40	(	(	PUNCT
dpc-3558	23	41	and	and	CCONJ
dpc-3558	23	42	ocular	ocular	ADJ
dpc-3558	23	43	)	)	PUNCT
dpc-3558	23	44	photosensitivity	photosensitivity	NOUN
dpc-3558	23	45	,	,	PUNCT
dpc-3558	23	46	and	and	CCONJ
dpc-3558	23	47	an	an	DET
dpc-3558	23	48	increased	increase	VERB
dpc-3558	23	49	risk	risk	NOUN
dpc-3558	23	50	for	for	ADP
dpc-3558	23	51	developing	develop	VERB
dpc-3558	23	52	a	a	DET
dpc-3558	23	53	host	host	NOUN
dpc-3558	23	54	of	of	ADP
dpc-3558	23	55	skin	skin	NOUN
dpc-3558	23	56	tumors	tumor	NOUN
dpc-3558	23	57	[	[	X
dpc-3558	23	58	2	2	NUM
dpc-3558	23	59	]	]	PUNCT
dpc-3558	23	60	.	.	PUNCT
dpc-3558	24	1	genetically	genetically	ADV
dpc-3558	24	2	,	,	PUNCT
dpc-3558	24	3	xp	xp	ADV
dpc-3558	24	4	is	be	AUX
dpc-3558	24	5	associated	associate	VERB
dpc-3558	24	6	with	with	ADP
dpc-3558	24	7	homozygous	homozygous	ADJ
dpc-3558	24	8	pathogenic	pathogenic	ADJ
dpc-3558	24	9	variants	variant	NOUN
dpc-3558	24	10	(	(	PUNCT
dpc-3558	24	11	pvs	pvs	PROPN
dpc-3558	24	12	)	)	PUNCT
dpc-3558	24	13	in	in	ADP
dpc-3558	24	14	seven	seven	NUM
dpc-3558	24	15	nucleotide	nucleotide	NOUN
dpc-3558	24	16	excision	excision	NOUN
dpc-3558	24	17	repair	repair	NOUN
dpc-3558	24	18	pathway	pathway	NOUN
dpc-3558	24	19	genes	gene	NOUN
dpc-3558	24	20	:	:	PUNCT
dpc-3558	24	21	xpa	xpa	PROPN
dpc-3558	24	22	,	,	PUNCT
dpc-3558	24	23	ercc3	ercc3	PROPN
dpc-3558	24	24	,	,	PUNCT
dpc-3558	24	25	xpc	xpc	PROPN
dpc-3558	24	26	,	,	PUNCT
dpc-3558	24	27	ercc2	ercc2	PROPN
dpc-3558	24	28	,	,	PUNCT
dpc-3558	24	29	ddb2	ddb2	PROPN
dpc-3558	24	30	,	,	PUNCT
dpc-3558	24	31	ercc4	ercc4	NOUN
dpc-3558	24	32	,	,	PUNCT
dpc-3558	24	33	ercc5	ercc5	NOUN
dpc-3558	24	34	and	and	CCONJ
dpc-3558	24	35	one	one	NUM
dpc-3558	24	36	clinical	clinical	ADJ
dpc-3558	24	37	variant	variant	NOUN
dpc-3558	24	38	(	(	PUNCT
dpc-3558	24	39	xpv	xpv	PROPN
dpc-3558	24	40	,	,	PUNCT
dpc-3558	24	41	xeroderma	xeroderma	NOUN
dpc-3558	24	42	pigmentosum	pigmentosum	PROPN
dpc-3558	24	43	variant	variant	NOUN
dpc-3558	24	44	)	)	PUNCT
dpc-3558	24	45	attributed	attribute	VERB
dpc-3558	24	46	to	to	ADP
dpc-3558	24	47	a	a	DET
dpc-3558	24	48	mutated	mutate	VERB
dpc-3558	24	49	polh	polh	NOUN
dpc-3558	24	50	gene	gene	NOUN
dpc-3558	24	51	[	[	X
dpc-3558	24	52	2	2	NUM
dpc-3558	24	53	]	]	PUNCT
dpc-3558	24	54	.	.	PUNCT
dpc-3558	25	1	the	the	DET
dpc-3558	25	2	most	most	ADV
dpc-3558	25	3	commonly	commonly	ADV
dpc-3558	25	4	mutated	mutate	VERB
dpc-3558	25	5	gene	gene	NOUN
dpc-3558	25	6	underlying	underlie	VERB
dpc-3558	25	7	xp	xp	INTJ
dpc-3558	25	8	in	in	ADP
dpc-3558	25	9	caucasians	caucasians	PROPN
dpc-3558	25	10	is	be	AUX
dpc-3558	25	11	xpc	xpc	PROPN
dpc-3558	25	12	group	group	NOUN
dpc-3558	25	13	c	c	PROPN
dpc-3558	25	14	(	(	PUNCT
dpc-3558	25	15	mim	mim	PROPN
dpc-3558	25	16	#	#	SYM
dpc-3558	25	17	278720	278720	NUM
dpc-3558	25	18	)	)	PUNCT
dpc-3558	26	1	[	[	X
dpc-3558	26	2	3	3	NUM
dpc-3558	26	3	]	]	PUNCT
dpc-3558	26	4	.	.	PUNCT
dpc-3558	27	1	the	the	DET
dpc-3558	27	2	clinical	clinical	ADJ
dpc-3558	27	3	phenotype	phenotype	NOUN
dpc-3558	27	4	in	in	ADP
dpc-3558	27	5	xp	xp	NOUN
dpc-3558	27	6	due	due	ADP
dpc-3558	27	7	to	to	ADP
dpc-3558	27	8	mutant	mutant	VERB
dpc-3558	27	9	xpc	xpc	PROPN
dpc-3558	27	10	alleles	allele	NOUN
dpc-3558	27	11	dependent	dependent	ADJ
dpc-3558	27	12	on	on	ADP
dpc-3558	27	13	sun	sun	NOUN
dpc-3558	27	14	exposure	exposure	NOUN
dpc-3558	27	15	and	and	CCONJ
dpc-3558	27	16	the	the	DET
dpc-3558	27	17	mutational	mutational	ADJ
dpc-3558	27	18	background	background	NOUN
dpc-3558	27	19	,	,	PUNCT
dpc-3558	27	20	hence	hence	ADV
dpc-3558	27	21	on	on	ADP
dpc-3558	27	22	the	the	DET
dpc-3558	27	23	geographical	geographical	ADJ
dpc-3558	27	24	origin	origin	NOUN
dpc-3558	27	25	[	[	X
dpc-3558	27	26	4	4	NUM
dpc-3558	27	27	]	]	PUNCT
dpc-3558	27	28	.	.	PUNCT
dpc-3558	28	1	the	the	DET
dpc-3558	28	2	incidence	incidence	NOUN
dpc-3558	28	3	of	of	ADP
dpc-3558	28	4	skin	skin	NOUN
dpc-3558	28	5	cancers	cancer	NOUN
dpc-3558	28	6	is	be	AUX
dpc-3558	28	7	1,000	1,000	NUM
dpc-3558	28	8	times	time	NOUN
dpc-3558	28	9	higher	high	ADJ
dpc-3558	28	10	in	in	ADP
dpc-3558	28	11	xp	xp	PROPN
dpc-3558	28	12	patients	patient	NOUN
dpc-3558	28	13	compared	compare	VERB
dpc-3558	28	14	with	with	ADP
dpc-3558	28	15	average	average	ADJ
dpc-3558	28	16	risk	risk	NOUN
dpc-3558	28	17	population	population	NOUN
dpc-3558	28	18	and	and	CCONJ
dpc-3558	28	19	a	a	DET
dpc-3558	28	20	major	major	ADJ
dpc-3558	28	21	contributor	contributor	NOUN
dpc-3558	28	22	to	to	ADP
dpc-3558	28	23	the	the	DET
dpc-3558	28	24	substantially	substantially	ADV
dpc-3558	28	25	decreased	decrease	VERB
dpc-3558	28	26	life	life	NOUN
dpc-3558	28	27	expectancy	expectancy	NOUN
dpc-3558	28	28	in	in	ADP
dpc-3558	28	29	xp	xp	PROPN
dpc-3558	28	30	cases	case	NOUN
dpc-3558	28	31	,	,	PUNCT
dpc-3558	28	32	around	around	ADV
dpc-3558	28	33	30	30	NUM
dpc-3558	28	34	years	year	NOUN
dpc-3558	29	1	[	[	X
dpc-3558	29	2	5	5	NUM
dpc-3558	29	3	]	]	PUNCT
dpc-3558	29	4	.	.	PUNCT
dpc-3558	30	1	these	these	DET
dpc-3558	30	2	patients	patient	NOUN
dpc-3558	30	3	have	have	VERB
dpc-3558	30	4	an	an	DET
dpc-3558	30	5	estimated	estimate	VERB
dpc-3558	30	6	10,000	10,000	NUM
dpc-3558	30	7	-	-	PUNCT
dpc-3558	30	8	fold	fold	ADJ
dpc-3558	30	9	increased	increase	VERB
dpc-3558	30	10	risk	risk	NOUN
dpc-3558	30	11	of	of	ADP
dpc-3558	30	12	non	non	ADJ
dpc-3558	30	13	-	-	ADJ
dpc-3558	30	14	melanoma	melanoma	ADJ
dpc-3558	30	15	skin	skin	NOUN
dpc-3558	30	16	cancer	cancer	NOUN
dpc-3558	30	17	,	,	PUNCT
dpc-3558	30	18	a	a	DET
dpc-3558	30	19	2,000	2,000	NUM
dpc-3558	30	20	-	-	PUNCT
dpc-3558	30	21	fold	fold	ADJ
dpc-3558	30	22	increased	increase	VERB
dpc-3558	30	23	risk	risk	NOUN
dpc-3558	30	24	of	of	ADP
dpc-3558	30	25	melanoma	melanoma	NOUN
dpc-3558	30	26	under	under	ADP
dpc-3558	30	27	the	the	DET
dpc-3558	30	28	age	age	NOUN
dpc-3558	30	29	of	of	ADP
dpc-3558	30	30	20	20	NUM
dpc-3558	30	31	[	[	SYM
dpc-3558	30	32	1	1	NUM
dpc-3558	30	33	]	]	PUNCT
dpc-3558	30	34	and	and	CCONJ
dpc-3558	30	35	the	the	DET
dpc-3558	30	36	first	first	ADJ
dpc-3558	30	37	skin	skin	NOUN
dpc-3558	30	38	lesions	lesion	NOUN
dpc-3558	30	39	may	may	AUX
dpc-3558	30	40	appear	appear	VERB
dpc-3558	30	41	as	as	ADV
dpc-3558	30	42	early	early	ADJ
dpc-3558	30	43	as	as	ADP
dpc-3558	30	44	eight	eight	NUM
dpc-3558	30	45	years	year	NOUN
dpc-3558	30	46	of	of	ADP
dpc-3558	30	47	age	age	NOUN
dpc-3558	30	48	[	[	X
dpc-3558	30	49	5	5	NUM
dpc-3558	30	50	]	]	PUNCT
dpc-3558	30	51	.	.	PUNCT
dpc-3558	31	1	familial	familial	ADJ
dpc-3558	31	2	melanoma	melanoma	NOUN
dpc-3558	31	3	syndrome	syndrome	NOUN
dpc-3558	31	4	(	(	PUNCT
dpc-3558	31	5	fms	fms	PROPN
dpc-3558	31	6	)	)	PUNCT
dpc-3558	31	7	is	be	AUX
dpc-3558	31	8	a	a	DET
dpc-3558	31	9	term	term	NOUN
dpc-3558	31	10	used	use	VERB
dpc-3558	31	11	to	to	PART
dpc-3558	31	12	describe	describe	VERB
dpc-3558	31	13	the	the	DET
dpc-3558	31	14	presence	presence	NOUN
dpc-3558	31	15	of	of	ADP
dpc-3558	31	16	two	two	NUM
dpc-3558	31	17	or	or	CCONJ
dpc-3558	31	18	more	more	ADJ
dpc-3558	31	19	cases	case	NOUN
dpc-3558	31	20	of	of	ADP
dpc-3558	31	21	cutaneous	cutaneous	ADJ
dpc-3558	31	22	melanoma	melanoma	NOUN
dpc-3558	31	23	in	in	ADP
dpc-3558	31	24	firstor	firstor	NOUN
dpc-3558	31	25	second	second	ADJ
dpc-3558	31	26	-	-	PUNCT
dpc-3558	31	27	degree	degree	NOUN
dpc-3558	31	28	relatives	relative	NOUN
dpc-3558	31	29	[	[	X
dpc-3558	31	30	6	6	NUM
dpc-3558	31	31	]	]	PUNCT
dpc-3558	31	32	.	.	PUNCT
dpc-3558	32	1	an	an	DET
dpc-3558	32	2	alternative	alternative	ADJ
dpc-3558	32	3	classification	classification	NOUN
dpc-3558	32	4	[	[	X
dpc-3558	32	5	7	7	NUM
dpc-3558	32	6	]	]	PUNCT
dpc-3558	32	7	refers	refer	VERB
dpc-3558	32	8	to	to	ADP
dpc-3558	32	9	these	these	DET
dpc-3558	32	10	cases	case	NOUN
dpc-3558	32	11	as	as	ADP
dpc-3558	32	12	melanoma	melanoma	NOUN
dpc-3558	32	13	dominant	dominant	ADJ
dpc-3558	32	14	syndrome	syndrome	NOUN
dpc-3558	32	15	when	when	SCONJ
dpc-3558	32	16	melanoma	melanoma	NOUN
dpc-3558	32	17	is	be	AUX
dpc-3558	32	18	the	the	DET
dpc-3558	32	19	first	first	ADJ
dpc-3558	32	20	or	or	CCONJ
dpc-3558	32	21	the	the	DET
dpc-3558	32	22	predominant	predominant	ADJ
dpc-3558	32	23	clinical	clinical	ADJ
dpc-3558	32	24	manifestation	manifestation	NOUN
dpc-3558	32	25	in	in	ADP
dpc-3558	32	26	a	a	DET
dpc-3558	32	27	family	family	NOUN
dpc-3558	32	28	.	.	PUNCT
dpc-3558	33	1	objectives	objective	NOUN
dpc-3558	33	2	here	here	ADV
dpc-3558	33	3	we	we	PRON
dpc-3558	33	4	report	report	VERB
dpc-3558	33	5	a	a	DET
dpc-3558	33	6	family	family	NOUN
dpc-3558	33	7	with	with	ADP
dpc-3558	33	8	cutaneous	cutaneous	ADJ
dpc-3558	33	9	melanomas	melanoma	NOUN
dpc-3558	33	10	with	with	ADP
dpc-3558	33	11	a	a	DET
dpc-3558	33	12	seemingly	seemingly	ADV
dpc-3558	33	13	autosomal	autosomal	ADJ
dpc-3558	33	14	dominant	dominant	ADJ
dpc-3558	33	15	inheritance	inheritance	NOUN
dpc-3558	33	16	pattern	pattern	NOUN
dpc-3558	33	17	without	without	ADP
dpc-3558	33	18	clear	clear	ADJ
dpc-3558	33	19	clinical	clinical	ADJ
dpc-3558	33	20	characteristics	characteristic	NOUN
dpc-3558	33	21	of	of	ADP
dpc-3558	33	22	xp	xp	PROPN
dpc-3558	33	23	,	,	PUNCT
dpc-3558	33	24	where	where	SCONJ
dpc-3558	33	25	a	a	DET
dpc-3558	33	26	homozygous	homozygous	ADJ
dpc-3558	33	27	xpc	xpc	NOUN
dpc-3558	33	28	inactivating	inactivating	NOUN
dpc-3558	33	29	pv	pv	CCONJ
dpc-3558	33	30	co	co	VERB
dpc-3558	33	31	-	-	VERB
dpc-3558	33	32	segregated	segregated	ADJ
dpc-3558	33	33	with	with	ADP
dpc-3558	33	34	the	the	DET
dpc-3558	33	35	phenotype	phenotype	NOUN
dpc-3558	33	36	,	,	PUNCT
dpc-3558	33	37	and	and	CCONJ
dpc-3558	33	38	a	a	DET
dpc-3558	33	39	mutant	mutant	ADJ
dpc-3558	33	40	mc1r	mc1r	NOUN
dpc-3558	33	41	allele	allele	NOUN
dpc-3558	33	42	seemingly	seemingly	ADV
dpc-3558	33	43	affected	affect	VERB
dpc-3558	33	44	the	the	DET
dpc-3558	33	45	clinical	clinical	ADJ
dpc-3558	33	46	melanoma	melanoma	NOUN
dpc-3558	33	47	phenotype	phenotype	NOUN
dpc-3558	33	48	.	.	PUNCT
dpc-3558	34	1	methods	method	NOUN
dpc-3558	34	2	the	the	DET
dpc-3558	34	3	proband	proband	NOUN
dpc-3558	34	4	(	(	PUNCT
dpc-3558	34	5	figure	figure	NOUN
dpc-3558	34	6	1	1	NUM
dpc-3558	34	7	)	)	PUNCT
dpc-3558	34	8	,	,	PUNCT
dpc-3558	34	9	individual	individual	ADJ
dpc-3558	34	10	ii.11	ii.11	NOUN
dpc-3558	34	11	,	,	PUNCT
dpc-3558	34	12	was	be	AUX
dpc-3558	34	13	referred	refer	VERB
dpc-3558	34	14	in	in	ADP
dpc-3558	34	15	2000	2000	NUM
dpc-3558	34	16	at	at	ADP
dpc-3558	34	17	age	age	NOUN
dpc-3558	34	18	28	28	NUM
dpc-3558	34	19	,	,	PUNCT
dpc-3558	34	20	after	after	ADP
dpc-3558	34	21	a	a	DET
dpc-3558	34	22	diagnosis	diagnosis	NOUN
dpc-3558	34	23	of	of	ADP
dpc-3558	34	24	melanoma	melanoma	NOUN
dpc-3558	34	25	and	and	CCONJ
dpc-3558	34	26	a	a	DET
dpc-3558	34	27	history	history	NOUN
dpc-3558	34	28	of	of	ADP
dpc-3558	34	29	death	death	NOUN
dpc-3558	34	30	of	of	ADP
dpc-3558	34	31	his	his	PRON
dpc-3558	34	32	older	old	ADJ
dpc-3558	34	33	brother	brother	NOUN
dpc-3558	34	34	from	from	ADP
dpc-3558	34	35	metastatic	metastatic	ADJ
dpc-3558	34	36	melanoma	melanoma	NOUN
dpc-3558	34	37	of	of	ADP
dpc-3558	34	38	the	the	DET
dpc-3558	34	39	lower	low	ADJ
dpc-3558	34	40	lip	lip	NOUN
dpc-3558	34	41	at	at	ADP
dpc-3558	34	42	age	age	NOUN
dpc-3558	34	43	38	38	NUM
dpc-3558	34	44	.	.	PUNCT
dpc-3558	35	1	since	since	SCONJ
dpc-3558	35	2	then	then	ADV
dpc-3558	35	3	,	,	PUNCT
dpc-3558	35	4	a	a	DET
dpc-3558	35	5	total	total	NOUN
dpc-3558	35	6	of	of	ADP
dpc-3558	35	7	24	24	NUM
dpc-3558	35	8	melanomas	melanoma	NOUN
dpc-3558	35	9	have	have	AUX
dpc-3558	35	10	been	be	AUX
dpc-3558	35	11	confirmed	confirm	VERB
dpc-3558	35	12	in	in	ADP
dpc-3558	35	13	the	the	DET
dpc-3558	35	14	proband	proband	NOUN
dpc-3558	35	15	.	.	PUNCT
dpc-3558	36	1	these	these	DET
dpc-3558	36	2	melanomas	melanoma	NOUN
dpc-3558	36	3	were	be	AUX
dpc-3558	36	4	mostly	mostly	ADV
dpc-3558	36	5	located	locate	VERB
dpc-3558	36	6	in	in	ADP
dpc-3558	36	7	the	the	DET
dpc-3558	36	8	head	head	NOUN
dpc-3558	36	9	(	(	PUNCT
dpc-3558	36	10	n	n	NOUN
dpc-3558	36	11	=	=	SYM
dpc-3558	36	12	19	19	NUM
dpc-3558	36	13	)	)	PUNCT
dpc-3558	36	14	and	and	CCONJ
dpc-3558	36	15	neck	neck	NOUN
dpc-3558	36	16	(	(	PUNCT
dpc-3558	36	17	n	n	NOUN
dpc-3558	36	18	=	=	SYM
dpc-3558	36	19	2	2	NUM
dpc-3558	36	20	)	)	PUNCT
dpc-3558	36	21	regions	region	NOUN
dpc-3558	36	22	,	,	PUNCT
dpc-3558	36	23	including	include	VERB
dpc-3558	36	24	the	the	DET
dpc-3558	36	25	scalp	scalp	NOUN
dpc-3558	36	26	(	(	PUNCT
dpc-3558	36	27	figure	figure	NOUN
dpc-3558	36	28	2	2	NUM
dpc-3558	36	29	)	)	PUNCT
dpc-3558	36	30	,	,	PUNCT
dpc-3558	36	31	and	and	CCONJ
dpc-3558	36	32	upper	upper	ADJ
dpc-3558	36	33	trunk	trunk	NOUN
dpc-3558	36	34	(	(	PUNCT
dpc-3558	36	35	n	n	NOUN
dpc-3558	36	36	=	=	SYM
dpc-3558	36	37	3	3	NUM
dpc-3558	36	38	)	)	PUNCT
dpc-3558	36	39	.	.	PUNCT
dpc-3558	37	1	the	the	DET
dpc-3558	37	2	majority	majority	NOUN
dpc-3558	37	3	(	(	PUNCT
dpc-3558	37	4	19/24	19/24	NUM
dpc-3558	37	5	)	)	PUNCT
dpc-3558	37	6	were	be	AUX
dpc-3558	37	7	in	in	ADP
dpc-3558	37	8	situ	situ	NOUN
dpc-3558	37	9	,	,	PUNCT
dpc-3558	37	10	three	three	NUM
dpc-3558	37	11	were	be	AUX
dpc-3558	37	12	thin	thin	ADJ
dpc-3558	37	13	melanomas	melanomas	NOUN
dpc-3558	37	14	(	(	PUNCT
dpc-3558	37	15	breslow	breslow	NOUN
dpc-3558	37	16	0.45	0.45	NUM
dpc-3558	37	17	mm	mm	PROPN
dpc-3558	37	18	,	,	PUNCT
dpc-3558	37	19	0.47	0.47	NUM
dpc-3558	37	20	mm	mm	NOUN
dpc-3558	37	21	and	and	CCONJ
dpc-3558	37	22	0.9	0.9	NUM
dpc-3558	37	23	mm	mm	NOUN
dpc-3558	37	24	)	)	PUNCT
dpc-3558	37	25	,	,	PUNCT
dpc-3558	37	26	one	one	NUM
dpc-3558	37	27	was	be	AUX
dpc-3558	37	28	1.4	1.4	NUM
dpc-3558	37	29	mm	mm	NOUN
dpc-3558	37	30	,	,	PUNCT
dpc-3558	37	31	and	and	CCONJ
dpc-3558	37	32	one	one	NUM
dpc-3558	37	33	was	be	AUX
dpc-3558	37	34	2.0	2.0	NUM
dpc-3558	37	35	mm	mm	NOUN
dpc-3558	37	36	.	.	PUNCT
dpc-3558	38	1	physical	physical	ADJ
dpc-3558	38	2	examination	examination	NOUN
dpc-3558	38	3	revealed	reveal	VERB
dpc-3558	38	4	brown	brown	ADJ
dpc-3558	38	5	hair	hair	NOUN
dpc-3558	38	6	and	and	CCONJ
dpc-3558	38	7	brown	brown	ADJ
dpc-3558	38	8	eyes	eye	NOUN
dpc-3558	38	9	,	,	PUNCT
dpc-3558	38	10	fitzpatrick	fitzpatrick	PROPN
dpc-3558	38	11	phototype	phototype	PROPN
dpc-3558	38	12	iii	iii	PROPN
dpc-3558	38	13	,	,	PUNCT
dpc-3558	38	14	sun	sun	NOUN
dpc-3558	38	15	damage	damage	NOUN
dpc-3558	38	16	on	on	ADP
dpc-3558	38	17	exposed	expose	VERB
dpc-3558	38	18	areas	area	NOUN
dpc-3558	38	19	with	with	ADP
dpc-3558	38	20	some	some	DET
dpc-3558	38	21	pigmented	pigmented	ADJ
dpc-3558	38	22	changes	change	NOUN
dpc-3558	38	23	,	,	PUNCT
dpc-3558	38	24	such	such	ADJ
dpc-3558	38	25	as	as	ADP
dpc-3558	38	26	solar	solar	ADJ
dpc-3558	38	27	lentigines	lentigo	NOUN
dpc-3558	38	28	.	.	PUNCT
dpc-3558	39	1	throughout	throughout	ADP
dpc-3558	39	2	20	20	NUM
dpc-3558	39	3	years	year	NOUN
dpc-3558	39	4	of	of	ADP
dpc-3558	39	5	follow	follow	NOUN
dpc-3558	39	6	-	-	PUNCT
dpc-3558	39	7	up	up	NOUN
dpc-3558	39	8	,	,	PUNCT
dpc-3558	39	9	he	he	PRON
dpc-3558	39	10	also	also	ADV
dpc-3558	39	11	presented	present	VERB
dpc-3558	39	12	two	two	NUM
dpc-3558	39	13	basal	basal	ADJ
dpc-3558	39	14	cell	cell	NOUN
dpc-3558	39	15	carcinomas	carcinoma	NOUN
dpc-3558	39	16	(	(	PUNCT
dpc-3558	39	17	bcc	bcc	PROPN
dpc-3558	39	18	)	)	PUNCT
dpc-3558	39	19	and	and	CCONJ
dpc-3558	39	20	one	one	NUM
dpc-3558	39	21	baso	baso	NOUN
dpc-3558	39	22	squamous	squamous	ADJ
dpc-3558	39	23	carcinoma	carcinoma	NOUN
dpc-3558	39	24	of	of	ADP
dpc-3558	39	25	the	the	DET
dpc-3558	39	26	head	head	NOUN
dpc-3558	39	27	and	and	CCONJ
dpc-3558	39	28	neck	neck	NOUN
dpc-3558	39	29	.	.	PUNCT
dpc-3558	40	1	history	history	NOUN
dpc-3558	40	2	of	of	ADP
dpc-3558	40	3	unprotected	unprotected	ADJ
dpc-3558	40	4	excessive	excessive	ADJ
dpc-3558	40	5	sun	sun	NOUN
dpc-3558	40	6	exposure	exposure	NOUN
dpc-3558	40	7	was	be	AUX
dpc-3558	40	8	reported	report	VERB
dpc-3558	40	9	.	.	PUNCT
dpc-3558	41	1	dermoscopy	dermoscopy	VERB
dpc-3558	41	2	of	of	ADP
dpc-3558	41	3	pigmented	pigmented	ADJ
dpc-3558	41	4	lesions	lesion	NOUN
dpc-3558	41	5	did	do	AUX
dpc-3558	41	6	not	not	PART
dpc-3558	41	7	show	show	VERB
dpc-3558	41	8	any	any	DET
dpc-3558	41	9	specific	specific	ADJ
dpc-3558	41	10	patterns	pattern	NOUN
dpc-3558	41	11	.	.	PUNCT
dpc-3558	42	1	all	all	DET
dpc-3558	42	2	consenting	consent	VERB
dpc-3558	42	3	siblings	sibling	NOUN
dpc-3558	42	4	(	(	PUNCT
dpc-3558	42	5	12	12	NUM
dpc-3558	42	6	)	)	PUNCT
dpc-3558	42	7	were	be	AUX
dpc-3558	42	8	examined	examine	VERB
dpc-3558	42	9	,	,	PUNCT
dpc-3558	42	10	and	and	CCONJ
dpc-3558	42	11	five	five	NUM
dpc-3558	42	12	of	of	ADP
dpc-3558	42	13	these	these	DET
dpc-3558	42	14	siblings	sibling	NOUN
dpc-3558	42	15	were	be	AUX
dpc-3558	42	16	diagnosed	diagnose	VERB
dpc-3558	42	17	with	with	ADP
dpc-3558	42	18	melanoma	melanoma	NOUN
dpc-3558	42	19	,	,	PUNCT
dpc-3558	42	20	(	(	PUNCT
dpc-3558	42	21	a	a	DET
dpc-3558	42	22	total	total	NOUN
dpc-3558	42	23	of	of	ADP
dpc-3558	42	24	7/13	7/13	NUM
dpc-3558	42	25	melanoma	melanoma	NOUN
dpc-3558	42	26	affected	affect	VERB
dpc-3558	42	27	siblings	sibling	NOUN
dpc-3558	42	28	)	)	PUNCT
dpc-3558	42	29	.	.	PUNCT
dpc-3558	43	1	of	of	ADP
dpc-3558	43	2	melanoma	melanoma	NOUN
dpc-3558	43	3	patients	patient	NOUN
dpc-3558	43	4	,	,	PUNCT
dpc-3558	43	5	the	the	DET
dpc-3558	43	6	majority	majority	NOUN
dpc-3558	43	7	had	have	VERB
dpc-3558	43	8	multiple	multiple	ADJ
dpc-3558	43	9	atypical	atypical	ADJ
dpc-3558	43	10	nevi	nevi	NOUN
dpc-3558	43	11	(	(	PUNCT
dpc-3558	43	12	three	three	NUM
dpc-3558	43	13	had	have	AUX
dpc-3558	43	14	more	more	ADJ
dpc-3558	43	15	than	than	ADP
dpc-3558	43	16	20	20	NUM
dpc-3558	43	17	,	,	PUNCT
dpc-3558	43	18	one	one	NUM
dpc-3558	43	19	had	have	VERB
dpc-3558	43	20	fewer	few	ADJ
dpc-3558	43	21	than	than	ADP
dpc-3558	43	22	10	10	NUM
dpc-3558	43	23	and	and	CCONJ
dpc-3558	43	24	one	one	NUM
dpc-3558	43	25	had	have	VERB
dpc-3558	43	26	none	none	NOUN
dpc-3558	43	27	)	)	PUNCT
dpc-3558	43	28	,	,	PUNCT
dpc-3558	43	29	all	all	PRON
dpc-3558	43	30	have	have	VERB
dpc-3558	43	31	a	a	DET
dpc-3558	43	32	relevant	relevant	ADJ
dpc-3558	43	33	history	history	NOUN
dpc-3558	43	34	of	of	ADP
dpc-3558	43	35	unprotected	unprotected	ADJ
dpc-3558	43	36	sun	sun	NOUN
dpc-3558	43	37	exposure	exposure	NOUN
dpc-3558	43	38	throughout	throughout	ADP
dpc-3558	43	39	life	life	NOUN
dpc-3558	43	40	.	.	PUNCT
dpc-3558	44	1	they	they	PRON
dpc-3558	44	2	did	do	AUX
dpc-3558	44	3	not	not	PART
dpc-3558	44	4	get	get	AUX
dpc-3558	44	5	sunburned	sunburn	VERB
dpc-3558	44	6	easily	easily	ADV
dpc-3558	44	7	and	and	CCONJ
dpc-3558	44	8	did	do	AUX
dpc-3558	44	9	not	not	PART
dpc-3558	44	10	have	have	VERB
dpc-3558	44	11	a	a	DET
dpc-3558	44	12	recollection	recollection	NOUN
dpc-3558	44	13	of	of	ADP
dpc-3558	44	14	many	many	ADJ
dpc-3558	44	15	blistering	blister	VERB
dpc-3558	44	16	despite	despite	SCONJ
dpc-3558	44	17	having	have	VERB
dpc-3558	44	18	a	a	DET
dpc-3558	44	19	long	long	ADJ
dpc-3558	44	20	history	history	NOUN
dpc-3558	44	21	of	of	ADP
dpc-3558	44	22	excessive	excessive	ADJ
dpc-3558	44	23	unprotected	unprotected	ADJ
dpc-3558	44	24	sun	sun	NOUN
dpc-3558	44	25	exposure	exposure	NOUN
dpc-3558	44	26	.	.	PUNCT
dpc-3558	45	1	most	most	ADJ
dpc-3558	45	2	of	of	ADP
dpc-3558	45	3	them	they	PRON
dpc-3558	45	4	have	have	VERB
dpc-3558	45	5	freckles	freckle	NOUN
dpc-3558	45	6	or	or	CCONJ
dpc-3558	45	7	solar	solar	ADJ
dpc-3558	45	8	melanosis	melanosis	NOUN
dpc-3558	45	9	,	,	PUNCT
dpc-3558	45	10	confirming	confirm	VERB
dpc-3558	45	11	the	the	DET
dpc-3558	45	12	sun	sun	NOUN
dpc-3558	45	13	-	-	PUNCT
dpc-3558	45	14	damaged	damage	VERB
dpc-3558	45	15	skin	skin	NOUN
dpc-3558	45	16	.	.	PUNCT
dpc-3558	46	1	clinical	clinical	ADJ
dpc-3558	46	2	characteristics	characteristic	NOUN
dpc-3558	46	3	of	of	ADP
dpc-3558	46	4	affected	affect	VERB
dpc-3558	46	5	individuals	individual	NOUN
dpc-3558	46	6	are	be	AUX
dpc-3558	46	7	shown	show	VERB
dpc-3558	46	8	in	in	ADP
dpc-3558	46	9	table	table	NOUN
dpc-3558	46	10	1	1	NUM
dpc-3558	46	11	.	.	PUNCT
dpc-3558	47	1	all	all	DET
dpc-3558	47	2	melanoma	melanoma	NOUN
dpc-3558	47	3	cases	case	NOUN
dpc-3558	47	4	reported	report	VERB
dpc-3558	47	5	a	a	DET
dpc-3558	47	6	history	history	NOUN
dpc-3558	47	7	of	of	ADP
dpc-3558	47	8	significant	significant	ADJ
dpc-3558	47	9	sun	sun	NOUN
dpc-3558	47	10	exposure	exposure	NOUN
dpc-3558	47	11	,	,	PUNCT
dpc-3558	47	12	fitzpatrick	fitzpatrick	PROPN
dpc-3558	47	13	type	type	PROPN
dpc-3558	47	14	iii	iii	PROPN
dpc-3558	47	15	,	,	PUNCT
dpc-3558	47	16	and	and	CCONJ
dpc-3558	47	17	solar	solar	ADJ
dpc-3558	47	18	lentigines	lentigo	NOUN
dpc-3558	47	19	in	in	ADP
dpc-3558	47	20	sun	sun	NOUN
dpc-3558	47	21	exposed	expose	VERB
dpc-3558	47	22	areas	area	NOUN
dpc-3558	47	23	.	.	PUNCT
dpc-3558	48	1	at	at	ADP
dpc-3558	48	2	the	the	DET
dpc-3558	48	3	time	time	NOUN
dpc-3558	48	4	of	of	ADP
dpc-3558	48	5	reporting	reporting	NOUN
dpc-3558	48	6	,	,	PUNCT
dpc-3558	48	7	five	five	NUM
dpc-3558	48	8	of	of	ADP
dpc-3558	48	9	the	the	DET
dpc-3558	48	10	six	six	NUM
dpc-3558	48	11	living	live	VERB
dpc-3558	48	12	affected	affect	VERB
dpc-3558	48	13	siblings	sibling	NOUN
dpc-3558	48	14	have	have	AUX
dpc-3558	48	15	had	have	VERB
dpc-3558	48	16	multiple	multiple	ADJ
dpc-3558	48	17	primary	primary	ADJ
dpc-3558	48	18	melanomas	melanomas	NOUN
dpc-3558	48	19	,	,	PUNCT
dpc-3558	48	20	varying	vary	VERB
dpc-3558	48	21	from	from	ADP
dpc-3558	48	22	three	three	NUM
dpc-3558	48	23	to	to	PART
dpc-3558	48	24	24	24	NUM
dpc-3558	48	25	tumors	tumor	NOUN
dpc-3558	48	26	per	per	ADP
dpc-3558	48	27	person	person	NOUN
dpc-3558	48	28	.	.	PUNCT
dpc-3558	49	1	age	age	NOUN
dpc-3558	49	2	range	range	NOUN
dpc-3558	49	3	at	at	ADP
dpc-3558	49	4	first	first	ADJ
dpc-3558	49	5	melanoma	melanoma	ADJ
dpc-3558	49	6	figure	figure	NOUN
dpc-3558	49	7	1	1	NUM
dpc-3558	49	8	.	.	PUNCT
dpc-3558	49	9	pedigree	pedigree	NOUN
dpc-3558	49	10	of	of	ADP
dpc-3558	49	11	proband	proband	NOUN
dpc-3558	49	12	(	(	PUNCT
dpc-3558	49	13	ii.11	ii.11	ADJ
dpc-3558	49	14	)	)	PUNCT
dpc-3558	49	15	family	family	NOUN
dpc-3558	49	16	.	.	PUNCT
dpc-3558	50	1	individuals	individual	NOUN
dpc-3558	50	2	affected	affect	VERB
dpc-3558	50	3	by	by	ADP
dpc-3558	50	4	cutaneous	cutaneous	ADJ
dpc-3558	50	5	melanoma	melanoma	NOUN
dpc-3558	50	6	are	be	AUX
dpc-3558	50	7	represented	represent	VERB
dpc-3558	50	8	in	in	ADP
dpc-3558	50	9	black	black	NOUN
dpc-3558	50	10	-	-	PUNCT
dpc-3558	50	11	filled	fill	VERB
dpc-3558	50	12	shapes	shape	NOUN
dpc-3558	50	13	,	,	PUNCT
dpc-3558	50	14	while	while	SCONJ
dpc-3558	50	15	white	white	ADJ
dpc-3558	50	16	shapes	shape	NOUN
dpc-3558	50	17	represent	represent	VERB
dpc-3558	50	18	individuals	individual	NOUN
dpc-3558	50	19	without	without	ADP
dpc-3558	50	20	history	history	NOUN
dpc-3558	50	21	of	of	ADP
dpc-3558	50	22	melanoma	melanoma	NOUN
dpc-3558	50	23	.	.	PUNCT
dpc-3558	51	1	original	original	ADJ
dpc-3558	51	2	article	article	NOUN
dpc-3558	51	3	|	|	ADV
dpc-3558	51	4	dermatol	dermatol	ADJ
dpc-3558	51	5	pract	pract	NOUN
dpc-3558	51	6	concept	concept	NOUN
dpc-3558	51	7	.	.	PUNCT
dpc-3558	52	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	52	2	3	3	NUM
dpc-3558	52	3	diagnosis	diagnosis	NOUN
dpc-3558	52	4	was	be	AUX
dpc-3558	52	5	22	22	NUM
dpc-3558	52	6	-	-	SYM
dpc-3558	52	7	45	45	NUM
dpc-3558	52	8	years	year	NOUN
dpc-3558	52	9	of	of	ADP
dpc-3558	52	10	age	age	NOUN
dpc-3558	52	11	.	.	PUNCT
dpc-3558	53	1	neither	neither	CCONJ
dpc-3558	53	2	visceral	visceral	ADJ
dpc-3558	53	3	metastasis	metastasis	NOUN
dpc-3558	53	4	nor	nor	CCONJ
dpc-3558	53	5	lymph	lymph	NOUN
dpc-3558	53	6	node	node	NOUN
dpc-3558	53	7	disease	disease	NOUN
dpc-3558	53	8	have	have	AUX
dpc-3558	53	9	been	be	AUX
dpc-3558	53	10	reported	report	VERB
dpc-3558	53	11	in	in	ADP
dpc-3558	53	12	any	any	PRON
dpc-3558	53	13	of	of	ADP
dpc-3558	53	14	the	the	DET
dpc-3558	53	15	six	six	NUM
dpc-3558	53	16	affected	affected	ADJ
dpc-3558	53	17	siblings	sibling	NOUN
dpc-3558	53	18	,	,	PUNCT
dpc-3558	53	19	and	and	CCONJ
dpc-3558	53	20	no	no	DET
dpc-3558	53	21	adjuvant	adjuvant	ADJ
dpc-3558	53	22	therapies	therapy	NOUN
dpc-3558	53	23	were	be	AUX
dpc-3558	53	24	given	give	VERB
dpc-3558	53	25	.	.	PUNCT
dpc-3558	54	1	interestingly	interestingly	ADV
dpc-3558	54	2	,	,	PUNCT
dpc-3558	54	3	no	no	DET
dpc-3558	54	4	relevant	relevant	ADJ
dpc-3558	54	5	ophthalmologic	ophthalmologic	ADJ
dpc-3558	54	6	condition	condition	NOUN
dpc-3558	54	7	has	have	AUX
dpc-3558	54	8	been	be	AUX
dpc-3558	54	9	diagnosed	diagnose	VERB
dpc-3558	54	10	in	in	ADP
dpc-3558	54	11	the	the	DET
dpc-3558	54	12	affected	affected	ADJ
dpc-3558	54	13	family	family	NOUN
dpc-3558	54	14	members	member	NOUN
dpc-3558	54	15	.	.	PUNCT
dpc-3558	55	1	the	the	DET
dpc-3558	55	2	siblings	sibling	NOUN
dpc-3558	55	3	were	be	AUX
dpc-3558	55	4	born	bear	VERB
dpc-3558	55	5	to	to	ADP
dpc-3558	55	6	consanguineous	consanguineous	ADJ
dpc-3558	55	7	(	(	PUNCT
dpc-3558	55	8	second	second	ADJ
dpc-3558	55	9	-	-	PUNCT
dpc-3558	55	10	degree	degree	NOUN
dpc-3558	55	11	cousins	cousin	NOUN
dpc-3558	55	12	)	)	PUNCT
dpc-3558	55	13	phenotypically	phenotypically	ADV
dpc-3558	55	14	healthy	healthy	ADJ
dpc-3558	55	15	parents	parent	NOUN
dpc-3558	55	16	;	;	PUNCT
dpc-3558	55	17	the	the	DET
dpc-3558	55	18	father	father	NOUN
dpc-3558	55	19	died	die	VERB
dpc-3558	55	20	at	at	ADP
dpc-3558	55	21	age	age	NOUN
dpc-3558	55	22	58	58	NUM
dpc-3558	55	23	without	without	ADP
dpc-3558	55	24	any	any	DET
dpc-3558	55	25	history	history	NOUN
dpc-3558	55	26	of	of	ADP
dpc-3558	55	27	skin	skin	NOUN
dpc-3558	55	28	cancer	cancer	NOUN
dpc-3558	55	29	.	.	PUNCT
dpc-3558	56	1	the	the	DET
dpc-3558	56	2	mother	mother	NOUN
dpc-3558	56	3	is	be	AUX
dpc-3558	56	4	still	still	ADV
dpc-3558	56	5	alive	alive	ADJ
dpc-3558	56	6	(	(	PUNCT
dpc-3558	56	7	age	age	NOUN
dpc-3558	56	8	86	86	NUM
dpc-3558	56	9	)	)	PUNCT
dpc-3558	56	10	,	,	PUNCT
dpc-3558	56	11	in	in	ADP
dpc-3558	56	12	good	good	ADJ
dpc-3558	56	13	health	health	NOUN
dpc-3558	56	14	and	and	CCONJ
dpc-3558	56	15	never	never	ADV
dpc-3558	56	16	had	have	VERB
dpc-3558	56	17	any	any	DET
dpc-3558	56	18	skin	skin	NOUN
dpc-3558	56	19	cancer	cancer	NOUN
dpc-3558	56	20	.	.	PUNCT
dpc-3558	57	1	occupational	occupational	ADJ
dpc-3558	57	2	exposure	exposure	NOUN
dpc-3558	57	3	to	to	ADP
dpc-3558	57	4	sun	sun	NOUN
dpc-3558	57	5	was	be	AUX
dpc-3558	57	6	suggested	suggest	VERB
dpc-3558	57	7	by	by	ADP
dpc-3558	57	8	the	the	DET
dpc-3558	57	9	fact	fact	NOUN
dpc-3558	57	10	that	that	SCONJ
dpc-3558	57	11	they	they	PRON
dpc-3558	57	12	were	be	AUX
dpc-3558	57	13	mostly	mostly	ADV
dpc-3558	57	14	farm	farm	NOUN
dpc-3558	57	15	laborers	laborer	NOUN
dpc-3558	57	16	.	.	PUNCT
dpc-3558	58	1	figure	figure	NOUN
dpc-3558	58	2	2	2	NUM
dpc-3558	58	3	demonstrates	demonstrate	VERB
dpc-3558	58	4	some	some	PRON
dpc-3558	58	5	of	of	ADP
dpc-3558	58	6	their	their	PRON
dpc-3558	58	7	clinical	clinical	ADJ
dpc-3558	58	8	features	feature	NOUN
dpc-3558	58	9	.	.	PUNCT
dpc-3558	59	1	this	this	DET
dpc-3558	59	2	study	study	NOUN
dpc-3558	59	3	was	be	AUX
dpc-3558	59	4	approved	approve	VERB
dpc-3558	59	5	by	by	ADP
dpc-3558	59	6	the	the	DET
dpc-3558	59	7	institutional	institutional	PROPN
dpc-3558	59	8	review	review	PROPN
dpc-3558	59	9	board	board	NOUN
dpc-3558	59	10	of	of	ADP
dpc-3558	59	11	universidade	universidade	PROPN
dpc-3558	59	12	federal	federal	PROPN
dpc-3558	59	13	de	de	PROPN
dpc-3558	59	14	minas	minas	PROPN
dpc-3558	59	15	gerais	gerais	PROPN
dpc-3558	59	16	(	(	PUNCT
dpc-3558	59	17	caae	caae	PROPN
dpc-3558	59	18	0472.0.203.240	0472.0.203.240	PROPN
dpc-3558	59	19	-	-	PUNCT
dpc-3558	59	20	11	11	NUM
dpc-3558	59	21	)	)	PUNCT
dpc-3558	59	22	.	.	PUNCT
dpc-3558	60	1	prior	prior	ADV
dpc-3558	60	2	to	to	ADP
dpc-3558	60	3	enrolment	enrolment	NOUN
dpc-3558	60	4	,	,	PUNCT
dpc-3558	60	5	written	write	VERB
dpc-3558	60	6	informed	informed	ADJ
dpc-3558	60	7	consent	consent	NOUN
dpc-3558	60	8	was	be	AUX
dpc-3558	60	9	obtained	obtain	VERB
dpc-3558	60	10	from	from	ADP
dpc-3558	60	11	all	all	DET
dpc-3558	60	12	patients	patient	NOUN
dpc-3558	60	13	.	.	PUNCT
dpc-3558	61	1	sanger	sanger	PROPN
dpc-3558	61	2	sequencing	sequence	VERB
dpc-3558	61	3	for	for	ADP
dpc-3558	61	4	the	the	DET
dpc-3558	61	5	cdkn2a	cdkn2a	PROPN
dpc-3558	61	6	gene	gene	NOUN
dpc-3558	61	7	,	,	PUNCT
dpc-3558	61	8	the	the	DET
dpc-3558	61	9	most	most	ADV
dpc-3558	61	10	common	common	ADJ
dpc-3558	61	11	high	high	ADJ
dpc-3558	61	12	penetrance	penetrance	NOUN
dpc-3558	61	13	melanoma	melanoma	NOUN
dpc-3558	61	14	susceptibility	susceptibility	NOUN
dpc-3558	61	15	gene	gene	NOUN
dpc-3558	61	16	,	,	PUNCT
dpc-3558	61	17	was	be	AUX
dpc-3558	61	18	initially	initially	ADV
dpc-3558	61	19	performed	perform	VERB
dpc-3558	61	20	.	.	PUNCT
dpc-3558	62	1	subsequently	subsequently	ADV
dpc-3558	62	2	,	,	PUNCT
dpc-3558	62	3	peripheral	peripheral	ADJ
dpc-3558	62	4	blood	blood	NOUN
dpc-3558	62	5	dna	dna	NOUN
dpc-3558	62	6	from	from	ADP
dpc-3558	62	7	individual	individual	ADJ
dpc-3558	62	8	ii.11	ii.11	NOUN
dpc-3558	62	9	was	be	AUX
dpc-3558	62	10	submitted	submit	VERB
dpc-3558	62	11	to	to	ADP
dpc-3558	62	12	whole	whole	ADJ
dpc-3558	62	13	-	-	PUNCT
dpc-3558	62	14	exome	exome	NOUN
dpc-3558	62	15	sequencing	sequencing	NOUN
dpc-3558	62	16	(	(	PUNCT
dpc-3558	62	17	wes	wes	PROPN
dpc-3558	62	18	)	)	PUNCT
dpc-3558	62	19	.	.	PUNCT
dpc-3558	63	1	the	the	DET
dpc-3558	63	2	vcf	vcf	NOUN
dpc-3558	63	3	file	file	NOUN
dpc-3558	63	4	was	be	AUX
dpc-3558	63	5	analyzed	analyze	VERB
dpc-3558	63	6	using	use	VERB
dpc-3558	63	7	mendel	mendel	PROPN
dpc-3558	63	8	,	,	PUNCT
dpc-3558	63	9	md	md	PROPN
dpc-3558	63	10	software	software	PROPN
dpc-3558	63	11	(	(	PUNCT
dpc-3558	63	12	http://mendel.medicina.ufmg.br	http://mendel.medicina.ufmg.br	PROPN
dpc-3558	63	13	)	)	PUNCT
dpc-3558	64	1	[	[	X
dpc-3558	64	2	8	8	NUM
dpc-3558	64	3	]	]	PUNCT
dpc-3558	64	4	as	as	ADV
dpc-3558	64	5	well	well	ADV
dpc-3558	64	6	as	as	ADP
dpc-3558	64	7	by	by	ADP
dpc-3558	64	8	ingenuity	ingenuity	NOUN
dpc-3558	64	9	®	®	NOUN
dpc-3558	64	10	variant	variant	NOUN
dpc-3558	64	11	analysistm	analysistm	NOUN
dpc-3558	64	12	software	software	PROPN
dpc-3558	64	13	(	(	PUNCT
dpc-3558	64	14	www.ingenuity.com/	www.ingenuity.com/	NOUN
dpc-3558	64	15	variants	variant	NOUN
dpc-3558	64	16	)	)	PUNCT
dpc-3558	64	17	.	.	PUNCT
dpc-3558	65	1	captured	capture	VERB
dpc-3558	65	2	sequences	sequence	NOUN
dpc-3558	65	3	were	be	AUX
dpc-3558	65	4	aligned	align	VERB
dpc-3558	65	5	with	with	ADP
dpc-3558	65	6	the	the	DET
dpc-3558	65	7	human	human	ADJ
dpc-3558	65	8	reference	reference	NOUN
dpc-3558	65	9	genome	genome	NOUN
dpc-3558	65	10	grch37	grch37	NOUN
dpc-3558	65	11	and	and	CCONJ
dpc-3558	65	12	a	a	DET
dpc-3558	65	13	sequence	sequence	NOUN
dpc-3558	65	14	of	of	ADP
dpc-3558	65	15	filters	filter	NOUN
dpc-3558	65	16	applied	apply	VERB
dpc-3558	65	17	.	.	PUNCT
dpc-3558	66	1	a	a	DET
dpc-3558	66	2	flow	flow	NOUN
dpc-3558	66	3	chart	chart	NOUN
dpc-3558	66	4	is	be	AUX
dpc-3558	66	5	shown	show	VERB
dpc-3558	66	6	in	in	ADP
dpc-3558	66	7	figure	figure	NOUN
dpc-3558	66	8	3	3	NUM
dpc-3558	66	9	.	.	PUNCT
dpc-3558	67	1	given	give	VERB
dpc-3558	67	2	the	the	DET
dpc-3558	67	3	autosomal	autosomal	ADJ
dpc-3558	67	4	recessive	recessive	ADJ
dpc-3558	67	5	inheritance	inheritance	NOUN
dpc-3558	67	6	pattern	pattern	NOUN
dpc-3558	67	7	in	in	ADP
dpc-3558	67	8	the	the	DET
dpc-3558	67	9	studied	studied	ADJ
dpc-3558	67	10	family	family	NOUN
dpc-3558	67	11	we	we	PRON
dpc-3558	67	12	focused	focus	VERB
dpc-3558	67	13	figure	figure	NOUN
dpc-3558	67	14	2	2	NUM
dpc-3558	67	15	.	.	PUNCT
dpc-3558	67	16	clinical	clinical	ADJ
dpc-3558	67	17	images	image	NOUN
dpc-3558	67	18	of	of	ADP
dpc-3558	67	19	affected	affected	ADJ
dpc-3558	67	20	individuals	individual	NOUN
dpc-3558	67	21	.	.	PUNCT
dpc-3558	68	1	(	(	PUNCT
dpc-3558	68	2	a	a	X
dpc-3558	68	3	)	)	PUNCT
dpc-3558	68	4	note	note	NOUN
dpc-3558	68	5	skin	skin	NOUN
dpc-3558	68	6	photoaging	photoaging	ADJ
dpc-3558	68	7	and	and	CCONJ
dpc-3558	68	8	solar	solar	ADJ
dpc-3558	68	9	lentigines	lentigo	NOUN
dpc-3558	68	10	on	on	ADP
dpc-3558	68	11	sun	sun	NOUN
dpc-3558	68	12	exposed	expose	VERB
dpc-3558	68	13	areas	area	NOUN
dpc-3558	68	14	of	of	ADP
dpc-3558	68	15	the	the	DET
dpc-3558	68	16	proband	proband	NOUN
dpc-3558	68	17	with	with	ADP
dpc-3558	68	18	a	a	DET
dpc-3558	68	19	large	large	ADJ
dpc-3558	68	20	scar	scar	NOUN
dpc-3558	68	21	from	from	ADP
dpc-3558	68	22	a	a	DET
dpc-3558	68	23	previous	previous	ADJ
dpc-3558	68	24	removed	removed	ADJ
dpc-3558	68	25	melanoma	melanoma	NOUN
dpc-3558	68	26	and	and	CCONJ
dpc-3558	68	27	a	a	DET
dpc-3558	68	28	new	new	ADJ
dpc-3558	68	29	melanoma	melanoma	NOUN
dpc-3558	68	30	on	on	ADP
dpc-3558	68	31	the	the	DET
dpc-3558	68	32	left	left	ADJ
dpc-3558	68	33	side	side	NOUN
dpc-3558	68	34	of	of	ADP
dpc-3558	68	35	the	the	DET
dpc-3558	68	36	scar	scar	NOUN
dpc-3558	68	37	.	.	PUNCT
dpc-3558	69	1	(	(	PUNCT
dpc-3558	69	2	b	b	X
dpc-3558	69	3	)	)	PUNCT
dpc-3558	69	4	melanoma	melanoma	NOUN
dpc-3558	69	5	on	on	ADP
dpc-3558	69	6	the	the	DET
dpc-3558	69	7	scalp	scalp	NOUN
dpc-3558	69	8	in	in	ADP
dpc-3558	69	9	the	the	DET
dpc-3558	69	10	proband	proband	NOUN
dpc-3558	69	11	,	,	PUNCT
dpc-3558	69	12	in	in	ADP
dpc-3558	69	13	a	a	DET
dpc-3558	69	14	relatively	relatively	ADV
dpc-3558	69	15	sun	sun	NOUN
dpc-3558	69	16	protected	protect	VERB
dpc-3558	69	17	area	area	NOUN
dpc-3558	69	18	.	.	PUNCT
dpc-3558	70	1	(	(	PUNCT
dpc-3558	70	2	c	c	X
dpc-3558	70	3	)	)	PUNCT
dpc-3558	70	4	two	two	NUM
dpc-3558	70	5	melanomas	melanoma	NOUN
dpc-3558	70	6	on	on	ADP
dpc-3558	70	7	the	the	DET
dpc-3558	70	8	forehead	forehead	NOUN
dpc-3558	70	9	of	of	ADP
dpc-3558	70	10	individual	individual	ADJ
dpc-3558	70	11	ii.8	ii.8	PROPN
dpc-3558	70	12	.	.	PUNCT
dpc-3558	71	1	(	(	PUNCT
dpc-3558	71	2	d	d	X
dpc-3558	71	3	)	)	PUNCT
dpc-3558	71	4	one	one	NUM
dpc-3558	71	5	melanoma	melanoma	NOUN
dpc-3558	71	6	in	in	ADP
dpc-3558	71	7	the	the	DET
dpc-3558	71	8	left	left	ADJ
dpc-3558	71	9	cervical	cervical	ADJ
dpc-3558	71	10	region	region	NOUN
dpc-3558	71	11	of	of	ADP
dpc-3558	71	12	individual	individual	ADJ
dpc-3558	71	13	ii.13	ii.13	PROPN
dpc-3558	71	14	on	on	ADP
dpc-3558	71	15	exposed	expose	VERB
dpc-3558	71	16	area	area	NOUN
dpc-3558	71	17	showing	show	VERB
dpc-3558	71	18	solar	solar	ADJ
dpc-3558	71	19	lentigines	lentigo	NOUN
dpc-3558	71	20	,	,	PUNCT
dpc-3558	71	21	surrounded	surround	VERB
dpc-3558	71	22	by	by	ADP
dpc-3558	71	23	pigmentary	pigmentary	ADJ
dpc-3558	71	24	changes	change	NOUN
dpc-3558	71	25	.	.	PUNCT
dpc-3558	72	1	table	table	NOUN
dpc-3558	72	2	1	1	NUM
dpc-3558	72	3	familial	familial	ADJ
dpc-3558	72	4	melanoma	melanoma	NOUN
dpc-3558	72	5	and	and	CCONJ
dpc-3558	72	6	their	their	PRON
dpc-3558	72	7	characteristics	characteristic	NOUN
dpc-3558	72	8	affected	affect	VERB
dpc-3558	72	9	individuals	individual	NOUN
dpc-3558	72	10	age	age	NOUN
dpc-3558	72	11	of	of	ADP
dpc-3558	72	12	first	first	ADJ
dpc-3558	72	13	melanoma	melanoma	NOUN
dpc-3558	72	14	number	number	NOUN
dpc-3558	72	15	of	of	ADP
dpc-3558	72	16	melanomas	melanomas	PROPN
dpc-3558	72	17	tumor(s	tumor(s	NOUN
dpc-3558	72	18	)	)	PUNCT
dpc-3558	72	19	localization(s	localization(s	NOUN
dpc-3558	72	20	)	)	PUNCT
dpc-3558	72	21	breslow	breslow	NOUN
dpc-3558	72	22	thickness	thickness	NOUN
dpc-3558	72	23	sun	sun	PROPN
dpc-3558	72	24	exposure	exposure	PROPN
dpc-3558	72	25	total	total	ADJ
dpc-3558	72	26	nevus	nevus	ADJ
dpc-3558	72	27	body	body	NOUN
dpc-3558	72	28	count	count	VERB
dpc-3558	72	29	other	other	ADJ
dpc-3558	72	30	skin	skin	NOUN
dpc-3558	72	31	cancers	cancer	NOUN
dpc-3558	72	32	ii.4	ii.4	PROPN
dpc-3558	72	33	45	45	NUM
dpc-3558	72	34	3	3	NUM
dpc-3558	72	35	head	head	NOUN
dpc-3558	72	36	(	(	PUNCT
dpc-3558	72	37	3	3	X
dpc-3558	72	38	)	)	PUNCT
dpc-3558	72	39	all	all	PRON
dpc-3558	72	40	in	in	ADP
dpc-3558	72	41	situ	situ	ADJ
dpc-3558	72	42	excessive	excessive	ADJ
dpc-3558	72	43	unprotected	unprotected	ADJ
dpc-3558	72	44	<	<	NOUN
dpc-3558	72	45	20	20	NUM
dpc-3558	72	46	none	none	NOUN
dpc-3558	72	47	ii.7	ii.7	NOUN
dpc-3558	72	48	33	33	NUM
dpc-3558	72	49	11	11	NUM
dpc-3558	72	50	head	head	NOUN
dpc-3558	72	51	(	(	PUNCT
dpc-3558	72	52	3	3	NUM
dpc-3558	72	53	)	)	PUNCT
dpc-3558	72	54	,	,	PUNCT
dpc-3558	72	55	neck	neck	NOUN
dpc-3558	72	56	(	(	PUNCT
dpc-3558	72	57	1	1	NUM
dpc-3558	72	58	)	)	PUNCT
dpc-3558	72	59	,	,	PUNCT
dpc-3558	72	60	limbs	limb	NOUN
dpc-3558	72	61	(	(	PUNCT
dpc-3558	72	62	2	2	NUM
dpc-3558	72	63	)	)	PUNCT
dpc-3558	72	64	and	and	CCONJ
dpc-3558	72	65	upper	upper	ADJ
dpc-3558	72	66	trunk	trunk	NOUN
dpc-3558	72	67	(	(	PUNCT
dpc-3558	72	68	5	5	NUM
dpc-3558	72	69	)	)	PUNCT
dpc-3558	72	70	all	all	PRON
dpc-3558	72	71	in	in	ADP
dpc-3558	72	72	situ	situ	ADJ
dpc-3558	72	73	excessive	excessive	ADJ
dpc-3558	72	74	unprotected	unprotected	ADJ
dpc-3558	72	75	20	20	NUM
dpc-3558	72	76	-	-	SYM
dpc-3558	72	77	100	100	NUM
dpc-3558	72	78	two	two	NUM
dpc-3558	72	79	bcc	bcc	PROPN
dpc-3558	72	80	ii.8	ii.8	PROPN
dpc-3558	72	81	35	35	NUM
dpc-3558	72	82	7	7	NUM
dpc-3558	72	83	head	head	NOUN
dpc-3558	72	84	(	(	PUNCT
dpc-3558	72	85	3	3	NUM
dpc-3558	72	86	)	)	PUNCT
dpc-3558	72	87	,	,	PUNCT
dpc-3558	72	88	neck	neck	NOUN
dpc-3558	72	89	(	(	PUNCT
dpc-3558	72	90	2	2	NUM
dpc-3558	72	91	)	)	PUNCT
dpc-3558	72	92	,	,	PUNCT
dpc-3558	72	93	and	and	CCONJ
dpc-3558	72	94	chest	chest	NOUN
dpc-3558	72	95	(	(	PUNCT
dpc-3558	72	96	2	2	NUM
dpc-3558	72	97	)	)	PUNCT
dpc-3558	72	98	0.24	0.24	NUM
dpc-3558	72	99	mm	mm	NOUN
dpc-3558	72	100	and	and	CCONJ
dpc-3558	72	101	6	6	NUM
dpc-3558	72	102	in	in	ADP
dpc-3558	72	103	situ	situ	ADJ
dpc-3558	72	104	excessive	excessive	ADJ
dpc-3558	72	105	unprotected	unprotected	ADJ
dpc-3558	72	106	20	20	NUM
dpc-3558	72	107	-	-	SYM
dpc-3558	72	108	100	100	NUM
dpc-3558	72	109	three	three	NUM
dpc-3558	72	110	bcc	bcc	PROPN
dpc-3558	72	111	ii.10	ii.10	VERB
dpc-3558	72	112	48	48	NUM
dpc-3558	72	113	1	1	NUM
dpc-3558	72	114	head	head	NOUN
dpc-3558	72	115	(	(	PUNCT
dpc-3558	72	116	scalp	scalp	NOUN
dpc-3558	72	117	)	)	PUNCT
dpc-3558	72	118	in	in	ADP
dpc-3558	72	119	situ	situ	ADJ
dpc-3558	72	120	excessive	excessive	ADJ
dpc-3558	72	121	unprotected	unprotected	ADJ
dpc-3558	72	122	20	20	NUM
dpc-3558	72	123	-	-	SYM
dpc-3558	72	124	100	100	NUM
dpc-3558	72	125	none	none	NOUN
dpc-3558	72	126	ii.11	ii.11	VERB
dpc-3558	72	127	28	28	NUM
dpc-3558	72	128	24	24	NUM
dpc-3558	72	129	head	head	NOUN
dpc-3558	72	130	(	(	PUNCT
dpc-3558	72	131	19	19	NUM
dpc-3558	72	132	)	)	PUNCT
dpc-3558	72	133	,	,	PUNCT
dpc-3558	72	134	neck	neck	NOUN
dpc-3558	72	135	(	(	PUNCT
dpc-3558	72	136	2	2	NUM
dpc-3558	72	137	)	)	PUNCT
dpc-3558	72	138	,	,	PUNCT
dpc-3558	72	139	and	and	CCONJ
dpc-3558	72	140	upper	upper	ADJ
dpc-3558	72	141	trunk	trunk	NOUN
dpc-3558	72	142	(	(	PUNCT
dpc-3558	72	143	3	3	NUM
dpc-3558	72	144	)	)	PUNCT
dpc-3558	72	145	0.45	0.45	NUM
dpc-3558	72	146	mm	mm	NOUN
dpc-3558	72	147	;	;	PUNCT
dpc-3558	72	148	0.47	0.47	NUM
dpc-3558	72	149	mm	mm	NOUN
dpc-3558	72	150	;	;	PUNCT
dpc-3558	72	151	0.9	0.9	NUM
dpc-3558	72	152	mm	mm	NOUN
dpc-3558	72	153	;	;	PUNCT
dpc-3558	72	154	1.4	1.4	NUM
dpc-3558	72	155	mm	mm	NOUN
dpc-3558	72	156	;	;	PUNCT
dpc-3558	72	157	2.0	2.0	NUM
dpc-3558	72	158	mm	mm	NOUN
dpc-3558	72	159	and	and	CCONJ
dpc-3558	72	160	19	19	NUM
dpc-3558	72	161	in	in	ADP
dpc-3558	72	162	situ	situ	ADJ
dpc-3558	72	163	excessive	excessive	ADJ
dpc-3558	72	164	unprotected	unprotected	ADJ
dpc-3558	72	165	>	>	ADP
dpc-3558	72	166	100	100	NUM
dpc-3558	72	167	two	two	NUM
dpc-3558	72	168	bcc	bcc	PROPN
dpc-3558	72	169	,	,	PUNCT
dpc-3558	72	170	one	one	NUM
dpc-3558	72	171	basosquamous	basosquamous	ADJ
dpc-3558	72	172	carcinoma	carcinoma	NOUN
dpc-3558	73	1	ii.13	ii.13	NOUN
dpc-3558	73	2	22	22	NUM
dpc-3558	73	3	7	7	NUM
dpc-3558	73	4	head	head	NOUN
dpc-3558	73	5	(	(	PUNCT
dpc-3558	73	6	3	3	NUM
dpc-3558	73	7	)	)	PUNCT
dpc-3558	73	8	,	,	PUNCT
dpc-3558	73	9	neck	neck	NOUN
dpc-3558	73	10	(	(	PUNCT
dpc-3558	73	11	3	3	NUM
dpc-3558	73	12	)	)	PUNCT
dpc-3558	73	13	and	and	CCONJ
dpc-3558	73	14	upper	upper	ADJ
dpc-3558	73	15	trunk	trunk	NOUN
dpc-3558	73	16	(	(	PUNCT
dpc-3558	73	17	1	1	NUM
dpc-3558	73	18	)	)	PUNCT
dpc-3558	73	19	0.23	0.23	NUM
dpc-3558	73	20	mm	mm	NOUN
dpc-3558	73	21	;	;	PUNCT
dpc-3558	73	22	0.36	0.36	NUM
dpc-3558	73	23	mm	mm	NOUN
dpc-3558	73	24	;	;	PUNCT
dpc-3558	73	25	2.3	2.3	NUM
dpc-3558	73	26	mm	mm	NOUN
dpc-3558	73	27	and	and	CCONJ
dpc-3558	73	28	4	4	NUM
dpc-3558	73	29	in	in	ADP
dpc-3558	73	30	situ	situ	ADJ
dpc-3558	73	31	excessive	excessive	ADJ
dpc-3558	73	32	unprotected	unprotected	ADJ
dpc-3558	73	33	>	>	ADP
dpc-3558	73	34	100	100	NUM
dpc-3558	73	35	one	one	NUM
dpc-3558	73	36	bcc	bcc	NOUN
dpc-3558	73	37	4	4	NUM
dpc-3558	73	38	original	original	ADJ
dpc-3558	73	39	article	article	NOUN
dpc-3558	73	40	|	|	ADV
dpc-3558	73	41	dermatol	dermatol	ADJ
dpc-3558	73	42	pract	pract	NOUN
dpc-3558	73	43	concept	concept	NOUN
dpc-3558	73	44	.	.	PUNCT
dpc-3558	74	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	74	2	homozygous	homozygous	ADJ
dpc-3558	74	3	variants	variant	NOUN
dpc-3558	74	4	only	only	ADV
dpc-3558	74	5	,	,	PUNCT
dpc-3558	74	6	it	it	PRON
dpc-3558	74	7	was	be	AUX
dpc-3558	74	8	narrowed	narrow	VERB
dpc-3558	74	9	down	down	ADP
dpc-3558	74	10	to	to	ADP
dpc-3558	74	11	eight	eight	NUM
dpc-3558	74	12	genes	gene	NOUN
dpc-3558	74	13	,	,	PUNCT
dpc-3558	74	14	of	of	ADP
dpc-3558	74	15	whom	whom	PRON
dpc-3558	74	16	xpc	xpc	PROPN
dpc-3558	74	17	was	be	AUX
dpc-3558	74	18	the	the	DET
dpc-3558	74	19	strongest	strong	ADJ
dpc-3558	74	20	candidate	candidate	NOUN
dpc-3558	74	21	.	.	PUNCT
dpc-3558	75	1	sequencing	sequence	VERB
dpc-3558	75	2	of	of	ADP
dpc-3558	75	3	xpc	xpc	PROPN
dpc-3558	75	4	demonstrated	demonstrate	VERB
dpc-3558	75	5	that	that	SCONJ
dpc-3558	75	6	the	the	DET
dpc-3558	75	7	clinically	clinically	ADV
dpc-3558	75	8	unaffected	unaffected	ADJ
dpc-3558	75	9	mother	mother	NOUN
dpc-3558	75	10	carried	carry	VERB
dpc-3558	75	11	the	the	DET
dpc-3558	75	12	heterozygous	heterozygous	ADJ
dpc-3558	75	13	xpc	xpc	NOUN
dpc-3558	75	14	variant	variant	NOUN
dpc-3558	75	15	p.arg307trp	p.arg307trp	PROPN
dpc-3558	75	16	(	(	PUNCT
dpc-3558	75	17	c.919c	c.919c	PROPN
dpc-3558	75	18	>	>	X
dpc-3558	75	19	t	t	PROPN
dpc-3558	75	20	)	)	PUNCT
dpc-3558	75	21	in	in	ADP
dpc-3558	75	22	exon	exon	NOUN
dpc-3558	75	23	8	8	NUM
dpc-3558	75	24	.	.	PUNCT
dpc-3558	76	1	all	all	DET
dpc-3558	76	2	five	five	NUM
dpc-3558	76	3	affected	affect	VERB
dpc-3558	76	4	individuals	individual	NOUN
dpc-3558	76	5	studied	study	VERB
dpc-3558	76	6	were	be	AUX
dpc-3558	76	7	homozygous	homozygous	ADJ
dpc-3558	76	8	(	(	PUNCT
dpc-3558	76	9	t	t	PROPN
dpc-3558	76	10	/	/	SYM
dpc-3558	76	11	t	t	PROPN
dpc-3558	76	12	)	)	PUNCT
dpc-3558	76	13	for	for	ADP
dpc-3558	76	14	this	this	DET
dpc-3558	76	15	sequence	sequence	NOUN
dpc-3558	76	16	variant	variant	NOUN
dpc-3558	76	17	.	.	PUNCT
dpc-3558	77	1	another	another	DET
dpc-3558	77	2	known	know	VERB
dpc-3558	77	3	pathogenic	pathogenic	ADJ
dpc-3558	77	4	variant	variant	NOUN
dpc-3558	77	5	(	(	PUNCT
dpc-3558	77	6	c.464t	c.464t	X
dpc-3558	77	7	>	>	X
dpc-3558	77	8	c	c	X
dpc-3558	77	9	;	;	PUNCT
dpc-3558	77	10	p.ile155thr	p.ile155thr	X
dpc-3558	77	11	)	)	PUNCT
dpc-3558	77	12	was	be	AUX
dpc-3558	77	13	detected	detect	VERB
dpc-3558	77	14	in	in	ADP
dpc-3558	77	15	the	the	DET
dpc-3558	77	16	mc1r	mc1r	PROPN
dpc-3558	77	17	gene	gene	NOUN
dpc-3558	77	18	(	(	PUNCT
dpc-3558	77	19	nm_002386.4	nm_002386.4	NOUN
dpc-3558	77	20	)	)	PUNCT
dpc-3558	77	21	by	by	ADP
dpc-3558	77	22	wes	wes	PROPN
dpc-3558	77	23	.	.	PUNCT
dpc-3558	78	1	three	three	NUM
dpc-3558	78	2	(	(	PUNCT
dpc-3558	78	3	ii.7	ii.7	NOUN
dpc-3558	78	4	,	,	PUNCT
dpc-3558	78	5	ii	ii	PROPN
dpc-3558	78	6	.	.	PROPN
dpc-3558	78	7	11	11	NUM
dpc-3558	78	8	and	and	CCONJ
dpc-3558	78	9	ii.13	ii.13	NUM
dpc-3558	78	10	)	)	PUNCT
dpc-3558	78	11	of	of	ADP
dpc-3558	78	12	the	the	DET
dpc-3558	78	13	five	five	NUM
dpc-3558	78	14	affected	affected	ADJ
dpc-3558	78	15	melanoma	melanoma	NOUN
dpc-3558	78	16	cases	case	NOUN
dpc-3558	78	17	who	who	PRON
dpc-3558	78	18	carried	carry	VERB
dpc-3558	78	19	the	the	DET
dpc-3558	78	20	xpc	xpc	PROPN
dpc-3558	78	21	homozygous	homozygous	ADJ
dpc-3558	78	22	variant	variant	NOUN
dpc-3558	78	23	harbored	harbor	VERB
dpc-3558	78	24	this	this	DET
dpc-3558	78	25	heterozygous	heterozygous	ADJ
dpc-3558	78	26	pv	pv	NOUN
dpc-3558	78	27	.	.	PUNCT
dpc-3558	79	1	these	these	DET
dpc-3558	79	2	three	three	NUM
dpc-3558	79	3	co	co	NOUN
dpc-3558	79	4	-	-	NOUN
dpc-3558	79	5	carriers	carrier	NOUN
dpc-3558	79	6	(	(	PUNCT
dpc-3558	79	7	xpc	xpc	PROPN
dpc-3558	79	8	and	and	CCONJ
dpc-3558	79	9	mc1r	mc1r	PROPN
dpc-3558	79	10	)	)	PUNCT
dpc-3558	79	11	carriers	carrier	NOUN
dpc-3558	79	12	displayed	display	VERB
dpc-3558	79	13	significantly	significantly	ADV
dpc-3558	79	14	worse	bad	ADJ
dpc-3558	79	15	disease	disease	NOUN
dpc-3558	79	16	phenotype	phenotype	NOUN
dpc-3558	79	17	compared	compare	VERB
dpc-3558	79	18	with	with	ADP
dpc-3558	79	19	the	the	DET
dpc-3558	79	20	two	two	NUM
dpc-3558	79	21	non	non	ADJ
dpc-3558	79	22	-	-	ADJ
dpc-3558	79	23	co	co	NOUN
dpc-3558	79	24	-	-	NOUN
dpc-3558	79	25	carriers	carrier	NOUN
dpc-3558	79	26	:	:	PUNCT
dpc-3558	79	27	higher	high	ADJ
dpc-3558	79	28	number	number	NOUN
dpc-3558	79	29	of	of	ADP
dpc-3558	79	30	melanomas	melanomas	NOUN
dpc-3558	79	31	per	per	ADP
dpc-3558	79	32	person	person	NOUN
dpc-3558	79	33	(	(	PUNCT
dpc-3558	79	34	14	14	NUM
dpc-3558	79	35	versus	versus	ADP
dpc-3558	79	36	5	5	NUM
dpc-3558	79	37	)	)	PUNCT
dpc-3558	79	38	,	,	PUNCT
dpc-3558	79	39	earlier	early	ADJ
dpc-3558	79	40	age	age	NOUN
dpc-3558	79	41	of	of	ADP
dpc-3558	79	42	melanoma	melanoma	ADJ
dpc-3558	79	43	diagnosis	diagnosis	NOUN
dpc-3558	79	44	(	(	PUNCT
dpc-3558	79	45	average	average	ADJ
dpc-3558	79	46	27.6	27.6	NUM
dpc-3558	79	47	years	year	NOUN
dpc-3558	79	48	versus	versus	ADP
dpc-3558	79	49	40	40	NUM
dpc-3558	79	50	years	year	NOUN
dpc-3558	79	51	)	)	PUNCT
dpc-3558	79	52	and	and	CCONJ
dpc-3558	79	53	thicker	thick	ADJ
dpc-3558	79	54	melanomas	melanomas	NOUN
dpc-3558	79	55	(	(	PUNCT
dpc-3558	79	56	three	three	NUM
dpc-3558	79	57	invasive	invasive	ADJ
dpc-3558	79	58	in	in	ADP
dpc-3558	79	59	co	co	NOUN
dpc-3558	79	60	-	-	NOUN
dpc-3558	79	61	carriers	carrier	NOUN
dpc-3558	79	62	versus	versus	ADP
dpc-3558	79	63	noninvasive	noninvasive	ADJ
dpc-3558	79	64	melanomas	melanomas	NOUN
dpc-3558	79	65	in	in	ADP
dpc-3558	79	66	non	non	ADJ
dpc-3558	79	67	-	-	ADJ
dpc-3558	79	68	co	co	NOUN
dpc-3558	79	69	-	-	NOUN
dpc-3558	79	70	carriers	carrier	NOUN
dpc-3558	79	71	,	,	PUNCT
dpc-3558	79	72	with	with	ADP
dpc-3558	79	73	mean	mean	NOUN
dpc-3558	79	74	on	on	ADP
dpc-3558	79	75	homozygous	homozygous	ADJ
dpc-3558	79	76	variants	variant	NOUN
dpc-3558	79	77	.	.	PUNCT
dpc-3558	80	1	all	all	DET
dpc-3558	80	2	seemingly	seemingly	ADV
dpc-3558	80	3	candidate	candidate	NOUN
dpc-3558	80	4	variants	variant	NOUN
dpc-3558	80	5	were	be	AUX
dpc-3558	80	6	confirmed	confirm	VERB
dpc-3558	80	7	by	by	ADP
dpc-3558	80	8	sanger	sanger	PROPN
dpc-3558	80	9	sequencing	sequencing	NOUN
dpc-3558	80	10	and	and	CCONJ
dpc-3558	80	11	cosegregation	cosegregation	NOUN
dpc-3558	80	12	was	be	AUX
dpc-3558	80	13	subsequently	subsequently	ADV
dpc-3558	80	14	carried	carry	VERB
dpc-3558	80	15	out	out	ADP
dpc-3558	80	16	in	in	ADP
dpc-3558	80	17	all	all	DET
dpc-3558	80	18	consenting	consent	VERB
dpc-3558	80	19	cases	case	NOUN
dpc-3558	80	20	(	(	PUNCT
dpc-3558	80	21	n	n	NOUN
dpc-3558	80	22	=	=	SYM
dpc-3558	80	23	15	15	NUM
dpc-3558	80	24	)	)	PUNCT
dpc-3558	80	25	using	use	VERB
dpc-3558	80	26	sanger	sanger	PROPN
dpc-3558	80	27	sequencing	sequencing	NOUN
dpc-3558	80	28	.	.	PUNCT
dpc-3558	81	1	to	to	PART
dpc-3558	81	2	further	far	ADV
dpc-3558	81	3	assess	assess	VERB
dpc-3558	81	4	the	the	DET
dpc-3558	81	5	putative	putative	ADJ
dpc-3558	81	6	clinical	clinical	ADJ
dpc-3558	81	7	significance	significance	NOUN
dpc-3558	81	8	of	of	ADP
dpc-3558	81	9	the	the	DET
dpc-3558	81	10	detected	detect	VERB
dpc-3558	81	11	xpc	xpc	PROPN
dpc-3558	81	12	sequence	sequence	NOUN
dpc-3558	81	13	variant	variant	NOUN
dpc-3558	81	14	and	and	CCONJ
dpc-3558	81	15	the	the	DET
dpc-3558	81	16	possibility	possibility	NOUN
dpc-3558	81	17	of	of	ADP
dpc-3558	81	18	residual	residual	ADJ
dpc-3558	81	19	protein	protein	NOUN
dpc-3558	81	20	function	function	NOUN
dpc-3558	81	21	,	,	PUNCT
dpc-3558	81	22	we	we	PRON
dpc-3558	81	23	performed	perform	VERB
dpc-3558	81	24	immunohistochemical	immunohistochemical	ADJ
dpc-3558	81	25	analysis	analysis	NOUN
dpc-3558	81	26	using	use	VERB
dpc-3558	81	27	xpc	xpc	PROPN
dpc-3558	81	28	antibody	antibody	NOUN
dpc-3558	81	29	(	(	PUNCT
dpc-3558	81	30	d-10	d-10	ADP
dpc-3558	81	31	:	:	PUNCT
dpc-3558	81	32	sc-74410	sc-74410	PROPN
dpc-3558	81	33	,	,	PUNCT
dpc-3558	81	34	santa	santa	PROPN
dpc-3558	81	35	cruz	cruz	PROPN
dpc-3558	81	36	biotechnology	biotechnology	PROPN
dpc-3558	81	37	)	)	PUNCT
dpc-3558	81	38	both	both	CCONJ
dpc-3558	81	39	on	on	ADP
dpc-3558	81	40	melanoma	melanoma	ADJ
dpc-3558	81	41	tissue	tissue	NOUN
dpc-3558	81	42	from	from	ADP
dpc-3558	81	43	the	the	DET
dpc-3558	81	44	proband	proband	NOUN
dpc-3558	81	45	and	and	CCONJ
dpc-3558	81	46	on	on	ADP
dpc-3558	81	47	normal	normal	ADJ
dpc-3558	81	48	mucosal	mucosal	NOUN
dpc-3558	81	49	tissue	tissue	NOUN
dpc-3558	81	50	from	from	ADP
dpc-3558	81	51	the	the	DET
dpc-3558	81	52	same	same	ADJ
dpc-3558	81	53	individual	individual	ADJ
dpc-3558	81	54	mucosa	mucosa	NOUN
dpc-3558	81	55	(	(	PUNCT
dpc-3558	81	56	serving	serve	VERB
dpc-3558	81	57	as	as	ADP
dpc-3558	81	58	control	control	NOUN
dpc-3558	81	59	)	)	PUNCT
dpc-3558	81	60	.	.	PUNCT
dpc-3558	82	1	results	result	NOUN
dpc-3558	82	2	cdkn2a	cdkn2a	VERB
dpc-3558	82	3	gene	gene	NOUN
dpc-3558	82	4	genotyping	genotyping	NOUN
dpc-3558	82	5	yielded	yield	VERB
dpc-3558	82	6	no	no	DET
dpc-3558	82	7	pvs	pvs	PROPN
dpc-3558	82	8	.	.	PUNCT
dpc-3558	83	1	wes	wes	PROPN
dpc-3558	83	2	showed	show	VERB
dpc-3558	83	3	46,452	46,452	NUM
dpc-3558	83	4	variants	variant	NOUN
dpc-3558	83	5	and	and	CCONJ
dpc-3558	83	6	,	,	PUNCT
dpc-3558	83	7	after	after	ADP
dpc-3558	83	8	a	a	DET
dpc-3558	83	9	series	series	NOUN
dpc-3558	83	10	of	of	ADP
dpc-3558	83	11	filtering	filtering	NOUN
dpc-3558	83	12	,	,	PUNCT
dpc-3558	83	13	exclusion	exclusion	NOUN
dpc-3558	83	14	of	of	ADP
dpc-3558	83	15	variants	variant	NOUN
dpc-3558	83	16	in	in	ADP
dpc-3558	83	17	our	our	PRON
dpc-3558	83	18	control	control	NOUN
dpc-3558	83	19	exomes	exome	NOUN
dpc-3558	83	20	bank	bank	PROPN
dpc-3558	83	21	and	and	CCONJ
dpc-3558	83	22	selection	selection	NOUN
dpc-3558	83	23	of	of	ADP
dpc-3558	83	24	figure	figure	NOUN
dpc-3558	83	25	3	3	NUM
dpc-3558	83	26	.	.	PUNCT
dpc-3558	83	27	flowchart	flowchart	NOUN
dpc-3558	83	28	of	of	ADP
dpc-3558	83	29	variant	variant	ADJ
dpc-3558	83	30	analyses	analysis	NOUN
dpc-3558	83	31	.	.	PUNCT
dpc-3558	84	1	original	original	ADJ
dpc-3558	84	2	article	article	NOUN
dpc-3558	84	3	|	|	ADV
dpc-3558	84	4	dermatol	dermatol	ADJ
dpc-3558	84	5	pract	pract	NOUN
dpc-3558	84	6	concept	concept	NOUN
dpc-3558	84	7	.	.	PUNCT
dpc-3558	85	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	85	2	5	5	NUM
dpc-3558	85	3	a	a	DET
dpc-3558	85	4	family	family	NOUN
dpc-3558	85	5	with	with	ADP
dpc-3558	85	6	atypical	atypical	ADJ
dpc-3558	85	7	xp	xp	NOUN
dpc-3558	85	8	presentation	presentation	NOUN
dpc-3558	85	9	age	age	NOUN
dpc-3558	85	10	in	in	ADP
dpc-3558	85	11	the	the	DET
dpc-3558	85	12	proband	proband	NOUN
dpc-3558	85	13	.	.	PUNCT
dpc-3558	86	1	late	late	ADJ
dpc-3558	86	2	onset	onset	NOUN
dpc-3558	86	3	of	of	ADP
dpc-3558	86	4	tumors	tumor	NOUN
dpc-3558	86	5	and	and	CCONJ
dpc-3558	86	6	late	late	ADJ
dpc-3558	86	7	diagnosis	diagnosis	NOUN
dpc-3558	86	8	of	of	ADP
dpc-3558	86	9	xp	xp	NOUN
dpc-3558	86	10	are	be	AUX
dpc-3558	86	11	uncommon	uncommon	ADJ
dpc-3558	86	12	but	but	CCONJ
dpc-3558	86	13	there	there	PRON
dpc-3558	86	14	are	be	VERB
dpc-3558	86	15	a	a	DET
dpc-3558	86	16	few	few	ADJ
dpc-3558	86	17	previously	previously	ADV
dpc-3558	86	18	reported	report	VERB
dpc-3558	86	19	cases	case	NOUN
dpc-3558	86	20	with	with	ADP
dpc-3558	86	21	distinct	distinct	ADJ
dpc-3558	86	22	phenotypes	phenotype	NOUN
dpc-3558	86	23	[	[	X
dpc-3558	86	24	10,11	10,11	NOUN
dpc-3558	86	25	]	]	X
dpc-3558	86	26	.	.	PUNCT
dpc-3558	87	1	to	to	ADP
dpc-3558	87	2	our	our	PRON
dpc-3558	87	3	knowledge	knowledge	NOUN
dpc-3558	87	4	,	,	PUNCT
dpc-3558	87	5	there	there	PRON
dpc-3558	87	6	are	be	VERB
dpc-3558	87	7	two	two	NUM
dpc-3558	87	8	reports	report	NOUN
dpc-3558	87	9	of	of	ADP
dpc-3558	87	10	xpc	xpc	NOUN
dpc-3558	87	11	-	-	PUNCT
dpc-3558	87	12	related	relate	VERB
dpc-3558	87	13	xp	xp	INTJ
dpc-3558	87	14	phenotype	phenotype	NOUN
dpc-3558	87	15	being	be	AUX
dpc-3558	87	16	diagnosed	diagnose	VERB
dpc-3558	87	17	in	in	ADP
dpc-3558	87	18	late	late	ADJ
dpc-3558	87	19	adulthood	adulthood	NOUN
dpc-3558	87	20	:	:	PUNCT
dpc-3558	87	21	an	an	DET
dpc-3558	87	22	83	83	NUM
dpc-3558	87	23	-	-	PUNCT
dpc-3558	87	24	year	year	NOUN
dpc-3558	87	25	-	-	PUNCT
dpc-3558	87	26	old	old	ADJ
dpc-3558	87	27	french	french	ADJ
dpc-3558	87	28	woman	woman	NOUN
dpc-3558	87	29	with	with	ADP
dpc-3558	87	30	multiple	multiple	ADJ
dpc-3558	87	31	melanomas	melanoma	NOUN
dpc-3558	87	32	whose	whose	DET
dpc-3558	87	33	unusual	unusual	ADJ
dpc-3558	87	34	long	long	ADJ
dpc-3558	87	35	-	-	PUNCT
dpc-3558	87	36	term	term	NOUN
dpc-3558	87	37	survival	survival	NOUN
dpc-3558	87	38	was	be	AUX
dpc-3558	87	39	attributed	attribute	VERB
dpc-3558	87	40	to	to	ADP
dpc-3558	87	41	a	a	DET
dpc-3558	87	42	lower	low	ADJ
dpc-3558	87	43	uv	uv	NOUN
dpc-3558	87	44	-	-	PUNCT
dpc-3558	87	45	radiation	radiation	NOUN
dpc-3558	87	46	exposure	exposure	NOUN
dpc-3558	87	47	and	and	CCONJ
dpc-3558	87	48	regular	regular	ADJ
dpc-3558	87	49	clinical	clinical	ADJ
dpc-3558	87	50	follow	follow	NOUN
dpc-3558	87	51	-	-	PUNCT
dpc-3558	87	52	up	up	NOUN
dpc-3558	87	53	and	and	CCONJ
dpc-3558	87	54	a	a	DET
dpc-3558	87	55	42	42	NUM
dpc-3558	87	56	-	-	PUNCT
dpc-3558	87	57	year	year	NOUN
dpc-3558	87	58	-	-	PUNCT
dpc-3558	87	59	old	old	ADJ
dpc-3558	87	60	caucasian	caucasian	ADJ
dpc-3558	87	61	man	man	NOUN
dpc-3558	87	62	with	with	ADP
dpc-3558	87	63	multiple	multiple	ADJ
dpc-3558	87	64	melanomas	melanomas	NOUN
dpc-3558	87	65	and	and	CCONJ
dpc-3558	87	66	a	a	DET
dpc-3558	87	67	missense	missense	NOUN
dpc-3558	87	68	pv	pv	ADV
dpc-3558	87	69	in	in	ADP
dpc-3558	87	70	the	the	DET
dpc-3558	87	71	xpc	xpc	PROPN
dpc-3558	87	72	gene	gene	NOUN
dpc-3558	87	73	that	that	PRON
dpc-3558	87	74	still	still	ADV
dpc-3558	87	75	retained	retain	VERB
dpc-3558	87	76	some	some	DET
dpc-3558	87	77	xpc	xpc	NOUN
dpc-3558	87	78	protein	protein	NOUN
dpc-3558	87	79	function	function	NOUN
dpc-3558	87	80	and	and	CCONJ
dpc-3558	87	81	,	,	PUNCT
dpc-3558	87	82	seemingly	seemingly	ADV
dpc-3558	87	83	contributing	contribute	VERB
dpc-3558	87	84	to	to	ADP
dpc-3558	87	85	late	late	ADJ
dpc-3558	87	86	xp	xp	INTJ
dpc-3558	88	1	diagnosis	diagnosis	NOUN
dpc-3558	89	1	[	[	X
dpc-3558	90	1	4,11	4,11	X
dpc-3558	90	2	]	]	X
dpc-3558	90	3	.	.	PUNCT
dpc-3558	91	1	xp	xp	PROPN
dpc-3558	91	2	typically	typically	ADV
dpc-3558	91	3	leads	lead	VERB
dpc-3558	91	4	to	to	ADP
dpc-3558	91	5	a	a	DET
dpc-3558	91	6	shortened	shorten	VERB
dpc-3558	91	7	life	life	NOUN
dpc-3558	91	8	span	span	NOUN
dpc-3558	91	9	,	,	PUNCT
dpc-3558	91	10	with	with	ADP
dpc-3558	91	11	cancer	cancer	NOUN
dpc-3558	91	12	related	relate	VERB
dpc-3558	91	13	death	death	NOUN
dpc-3558	91	14	usually	usually	ADV
dpc-3558	91	15	occurring	occur	VERB
dpc-3558	91	16	at	at	ADP
dpc-3558	91	17	30	30	NUM
dpc-3558	91	18	-	-	SYM
dpc-3558	91	19	40	40	NUM
dpc-3558	91	20	years	year	NOUN
dpc-3558	91	21	of	of	ADP
dpc-3558	91	22	age	age	NOUN
dpc-3558	91	23	[	[	X
dpc-3558	91	24	12	12	NUM
dpc-3558	91	25	]	]	PUNCT
dpc-3558	91	26	.	.	PUNCT
dpc-3558	92	1	in	in	ADP
dpc-3558	92	2	the	the	DET
dpc-3558	92	3	case	case	NOUN
dpc-3558	92	4	described	describe	VERB
dpc-3558	92	5	herein	herein	NOUN
dpc-3558	92	6	all	all	PRON
dpc-3558	92	7	but	but	SCONJ
dpc-3558	92	8	one	one	NUM
dpc-3558	92	9	patient	patient	NOUN
dpc-3558	92	10	are	be	AUX
dpc-3558	92	11	alive	alive	ADJ
dpc-3558	92	12	aged	aged	ADJ
dpc-3558	92	13	41	41	NUM
dpc-3558	92	14	-	-	SYM
dpc-3558	92	15	62	62	NUM
dpc-3558	92	16	years	year	NOUN
dpc-3558	92	17	,	,	PUNCT
dpc-3558	92	18	at	at	ADP
dpc-3558	92	19	the	the	DET
dpc-3558	92	20	time	time	NOUN
dpc-3558	92	21	of	of	ADP
dpc-3558	92	22	reporting	reporting	NOUN
dpc-3558	92	23	(	(	PUNCT
dpc-3558	92	24	figure	figure	NOUN
dpc-3558	92	25	1	1	NUM
dpc-3558	92	26	)	)	PUNCT
dpc-3558	92	27	.	.	PUNCT
dpc-3558	93	1	the	the	DET
dpc-3558	93	2	less	less	ADV
dpc-3558	93	3	severe	severe	ADJ
dpc-3558	93	4	phenotype	phenotype	NOUN
dpc-3558	93	5	and	and	CCONJ
dpc-3558	93	6	the	the	DET
dpc-3558	93	7	less	less	ADV
dpc-3558	93	8	pronounced	pronounced	ADJ
dpc-3558	93	9	effect	effect	NOUN
dpc-3558	93	10	on	on	ADP
dpc-3558	93	11	early	early	ADJ
dpc-3558	93	12	age	age	NOUN
dpc-3558	93	13	mortality	mortality	NOUN
dpc-3558	93	14	in	in	ADP
dpc-3558	93	15	this	this	DET
dpc-3558	93	16	family	family	NOUN
dpc-3558	93	17	suggests	suggest	VERB
dpc-3558	93	18	that	that	SCONJ
dpc-3558	93	19	the	the	DET
dpc-3558	93	20	xpc	xpc	PROPN
dpc-3558	93	21	mutated	mutate	VERB
dpc-3558	93	22	protein	protein	NOUN
dpc-3558	93	23	is	be	AUX
dpc-3558	93	24	still	still	ADV
dpc-3558	93	25	capable	capable	ADJ
dpc-3558	93	26	of	of	ADP
dpc-3558	93	27	exerting	exert	VERB
dpc-3558	93	28	some	some	DET
dpc-3558	93	29	residual	residual	ADJ
dpc-3558	93	30	activity	activity	NOUN
dpc-3558	93	31	and	and	CCONJ
dpc-3558	93	32	repair	repair	VERB
dpc-3558	93	33	dna	dna	NOUN
dpc-3558	93	34	damage	damage	NOUN
dpc-3558	93	35	,	,	PUNCT
dpc-3558	93	36	as	as	SCONJ
dpc-3558	93	37	previously	previously	ADV
dpc-3558	93	38	suggested	suggest	VERB
dpc-3558	93	39	[	[	X
dpc-3558	93	40	4	4	NUM
dpc-3558	93	41	]	]	PUNCT
dpc-3558	93	42	.	.	PUNCT
dpc-3558	94	1	being	be	AUX
dpc-3558	94	2	a	a	DET
dpc-3558	94	3	recessive	recessive	ADJ
dpc-3558	94	4	condition	condition	NOUN
dpc-3558	94	5	,	,	PUNCT
dpc-3558	94	6	it	it	PRON
dpc-3558	94	7	is	be	AUX
dpc-3558	94	8	expected	expect	VERB
dpc-3558	94	9	that	that	SCONJ
dpc-3558	94	10	around	around	ADV
dpc-3558	94	11	25	25	NUM
dpc-3558	94	12	%	%	NOUN
dpc-3558	94	13	of	of	ADP
dpc-3558	94	14	the	the	DET
dpc-3558	94	15	offspring	offspring	NOUN
dpc-3558	94	16	would	would	AUX
dpc-3558	94	17	be	be	AUX
dpc-3558	94	18	affected	affect	VERB
dpc-3558	94	19	.	.	PUNCT
dpc-3558	95	1	in	in	ADP
dpc-3558	95	2	this	this	DET
dpc-3558	95	3	family	family	NOUN
dpc-3558	95	4	,	,	PUNCT
dpc-3558	95	5	seven	seven	NUM
dpc-3558	95	6	of	of	ADP
dpc-3558	95	7	the	the	DET
dpc-3558	95	8	13	13	NUM
dpc-3558	95	9	siblings	sibling	NOUN
dpc-3558	95	10	are	be	AUX
dpc-3558	95	11	affected	affect	VERB
dpc-3558	95	12	(	(	PUNCT
dpc-3558	95	13	53.8	53.8	NUM
dpc-3558	95	14	%	%	NOUN
dpc-3558	95	15	)	)	PUNCT
dpc-3558	95	16	,	,	PUNCT
dpc-3558	95	17	with	with	ADP
dpc-3558	95	18	an	an	DET
dpc-3558	95	19	extraordinary	extraordinary	ADJ
dpc-3558	95	20	higher	high	ADJ
dpc-3558	95	21	number	number	NOUN
dpc-3558	95	22	of	of	ADP
dpc-3558	95	23	melanomas	melanomas	NOUN
dpc-3558	95	24	(	(	PUNCT
dpc-3558	95	25	n	n	NOUN
dpc-3558	95	26	=	=	SYM
dpc-3558	95	27	43	43	NUM
dpc-3558	95	28	)	)	PUNCT
dpc-3558	95	29	compared	compare	VERB
dpc-3558	95	30	with	with	ADP
dpc-3558	95	31	non	non	ADJ
dpc-3558	95	32	-	-	ADJ
dpc-3558	95	33	melanoma	melanoma	ADJ
dpc-3558	95	34	skin	skin	NOUN
dpc-3558	95	35	cancers	cancer	NOUN
dpc-3558	95	36	(	(	PUNCT
dpc-3558	95	37	n=	n=	ADJ
dpc-3558	95	38	9	9	NUM
dpc-3558	95	39	)	)	PUNCT
dpc-3558	95	40	,	,	PUNCT
dpc-3558	95	41	an	an	DET
dpc-3558	95	42	unusual	unusual	ADJ
dpc-3558	95	43	tumor	tumor	NOUN
dpc-3558	95	44	distribution	distribution	NOUN
dpc-3558	95	45	to	to	ADP
dpc-3558	95	46	the	the	DET
dpc-3558	95	47	one	one	NOUN
dpc-3558	95	48	usually	usually	ADV
dpc-3558	95	49	seen	see	VERB
dpc-3558	95	50	in	in	ADP
dpc-3558	95	51	xp	xp	INTJ
dpc-3558	95	52	patients	patient	NOUN
dpc-3558	95	53	–	–	PUNCT
dpc-3558	95	54	carcinomas	carcinoma	NOUN
dpc-3558	95	55	are	be	AUX
dpc-3558	95	56	five	five	NUM
dpc-3558	95	57	times	time	NOUN
dpc-3558	95	58	more	more	ADV
dpc-3558	95	59	common	common	ADJ
dpc-3558	95	60	than	than	ADP
dpc-3558	95	61	melanomas	melanomas	NOUN
dpc-3558	96	1	[	[	X
dpc-3558	96	2	1	1	NUM
dpc-3558	96	3	]	]	PUNCT
dpc-3558	96	4	.	.	PUNCT
dpc-3558	97	1	additional	additional	ADJ
dpc-3558	97	2	clinically	clinically	ADV
dpc-3558	97	3	unique	unique	ADJ
dpc-3558	97	4	features	feature	NOUN
dpc-3558	97	5	in	in	ADP
dpc-3558	97	6	this	this	DET
dpc-3558	97	7	family	family	NOUN
dpc-3558	97	8	that	that	PRON
dpc-3558	97	9	have	have	AUX
dpc-3558	97	10	led	lead	VERB
dpc-3558	97	11	to	to	PART
dpc-3558	97	12	xp	xp	INTJ
dpc-3558	97	13	not	not	PART
dpc-3558	97	14	even	even	ADV
dpc-3558	97	15	being	be	AUX
dpc-3558	97	16	considered	consider	VERB
dpc-3558	97	17	as	as	ADP
dpc-3558	97	18	a	a	DET
dpc-3558	97	19	possible	possible	ADJ
dpc-3558	97	20	diagnosis	diagnosis	NOUN
dpc-3558	97	21	prior	prior	ADV
dpc-3558	97	22	to	to	ADP
dpc-3558	97	23	genetic	genetic	ADJ
dpc-3558	97	24	analysis	analysis	NOUN
dpc-3558	97	25	,	,	PUNCT
dpc-3558	97	26	were	be	AUX
dpc-3558	97	27	the	the	DET
dpc-3558	97	28	fact	fact	NOUN
dpc-3558	97	29	that	that	SCONJ
dpc-3558	97	30	melanomas	melanoma	NOUN
dpc-3558	97	31	were	be	AUX
dpc-3558	97	32	not	not	PART
dpc-3558	97	33	only	only	ADV
dpc-3558	97	34	breslow	breslow	VERB
dpc-3558	97	35	thickness	thickness	NOUN
dpc-3558	97	36	of	of	ADP
dpc-3558	97	37	0.17	0.17	NUM
dpc-3558	97	38	mm	mm	NOUN
dpc-3558	97	39	in	in	ADP
dpc-3558	97	40	carriers	carrier	NOUN
dpc-3558	97	41	,	,	PUNCT
dpc-3558	97	42	versus	versus	ADP
dpc-3558	97	43	0.017	0.017	NUM
dpc-3558	97	44	mm	mm	NOUN
dpc-3558	97	45	in	in	ADP
dpc-3558	97	46	non	non	ADJ
dpc-3558	97	47	-	-	NOUN
dpc-3558	97	48	carriers	carrier	NOUN
dpc-3558	97	49	)	)	PUNCT
dpc-3558	97	50	.	.	PUNCT
dpc-3558	98	1	our	our	PRON
dpc-3558	98	2	data	datum	NOUN
dpc-3558	98	3	shows	show	VERB
dpc-3558	98	4	that	that	SCONJ
dpc-3558	98	5	the	the	DET
dpc-3558	98	6	median	median	ADJ
dpc-3558	98	7	number	number	NOUN
dpc-3558	98	8	of	of	ADP
dpc-3558	98	9	non	non	ADJ
dpc-3558	98	10	-	-	ADJ
dpc-3558	98	11	melanoma	melanoma	ADJ
dpc-3558	98	12	skin	skin	NOUN
dpc-3558	98	13	cancer	cancer	NOUN
dpc-3558	98	14	(	(	PUNCT
dpc-3558	98	15	nmsc	nmsc	NOUN
dpc-3558	98	16	)	)	PUNCT
dpc-3558	98	17	per	per	ADP
dpc-3558	98	18	person	person	NOUN
dpc-3558	98	19	among	among	ADP
dpc-3558	98	20	mc1r	mc1r	NOUN
dpc-3558	98	21	wild	wild	ADJ
dpc-3558	98	22	-	-	PUNCT
dpc-3558	98	23	type	type	NOUN
dpc-3558	98	24	xp	xp	NOUN
dpc-3558	98	25	-	-	NOUN
dpc-3558	98	26	c	c	NOUN
dpc-3558	98	27	individuals	individual	NOUN
dpc-3558	98	28	was	be	AUX
dpc-3558	98	29	1.5	1.5	NUM
dpc-3558	98	30	(	(	PUNCT
dpc-3558	98	31	three	three	NUM
dpc-3558	98	32	bcc	bcc	NOUN
dpc-3558	98	33	in	in	ADP
dpc-3558	98	34	two	two	NUM
dpc-3558	98	35	subjects	subject	NOUN
dpc-3558	98	36	)	)	PUNCT
dpc-3558	98	37	.	.	PUNCT
dpc-3558	99	1	in	in	ADP
dpc-3558	99	2	contrast	contrast	NOUN
dpc-3558	99	3	,	,	PUNCT
dpc-3558	99	4	among	among	ADP
dpc-3558	99	5	carriers	carrier	NOUN
dpc-3558	99	6	of	of	ADP
dpc-3558	99	7	the	the	DET
dpc-3558	99	8	i155	i155	PROPN
dpc-3558	99	9	t	t	NOUN
dpc-3558	99	10	variant	variant	NOUN
dpc-3558	99	11	,	,	PUNCT
dpc-3558	99	12	the	the	DET
dpc-3558	99	13	median	median	ADJ
dpc-3558	99	14	number	number	NOUN
dpc-3558	99	15	of	of	ADP
dpc-3558	99	16	nmsc	nmsc	NOUN
dpc-3558	99	17	was	be	AUX
dpc-3558	99	18	2.0	2.0	NUM
dpc-3558	99	19	,	,	PUNCT
dpc-3558	99	20	with	with	ADP
dpc-3558	99	21	six	six	NUM
dpc-3558	99	22	tumors	tumor	NOUN
dpc-3558	99	23	occurring	occur	VERB
dpc-3558	99	24	in	in	ADP
dpc-3558	99	25	three	three	NUM
dpc-3558	99	26	individuals	individual	NOUN
dpc-3558	99	27	.	.	PUNCT
dpc-3558	100	1	the	the	DET
dpc-3558	100	2	xpc	xpc	PROPN
dpc-3558	100	3	c.919c	c.919c	PROPN
dpc-3558	100	4	>	>	PROPN
dpc-3558	100	5	t;p.arg307trp	t;p.arg307trp	PROPN
dpc-3558	100	6	variant	variant	NOUN
dpc-3558	100	7	is	be	AUX
dpc-3558	100	8	predicted	predict	VERB
dpc-3558	100	9	to	to	PART
dpc-3558	100	10	be	be	AUX
dpc-3558	100	11	pathogenic	pathogenic	ADJ
dpc-3558	100	12	by	by	ADP
dpc-3558	100	13	several	several	ADJ
dpc-3558	100	14	different	different	ADJ
dpc-3558	100	15	bioinformatics	bioinformatics	NOUN
dpc-3558	100	16	tools	tool	NOUN
dpc-3558	100	17	:	:	PUNCT
dpc-3558	100	18	disease	disease	NOUN
dpc-3558	100	19	causing	cause	VERB
dpc-3558	100	20	by	by	ADP
dpc-3558	100	21	mutationtaster	mutationtaster	NOUN
dpc-3558	100	22	(	(	PUNCT
dpc-3558	100	23	http://www.mutationtaster	http://www.mutationtaster	NOUN
dpc-3558	100	24	.org/	.org/	PUNCT
dpc-3558	100	25	)	)	PUNCT
dpc-3558	100	26	,	,	PUNCT
dpc-3558	100	27	probably	probably	ADV
dpc-3558	100	28	damaging	damage	VERB
dpc-3558	100	29	by	by	ADP
dpc-3558	100	30	polyphen-2	polyphen-2	X
dpc-3558	100	31	with	with	ADP
dpc-3558	100	32	a	a	DET
dpc-3558	100	33	score	score	NOUN
dpc-3558	100	34	of	of	ADP
dpc-3558	100	35	1.0	1.0	NUM
dpc-3558	100	36	(	(	PUNCT
dpc-3558	100	37	http://genetics.bwh.harvard.edu/pph2/	http://genetics.bwh.harvard.edu/pph2/	X
dpc-3558	100	38	)	)	PUNCT
dpc-3558	100	39	and	and	CCONJ
dpc-3558	100	40	deleterious	deleterious	ADJ
dpc-3558	100	41	by	by	ADP
dpc-3558	100	42	the	the	DET
dpc-3558	100	43	protein	protein	NOUN
dpc-3558	100	44	variation	variation	NOUN
dpc-3558	100	45	effect	effect	NOUN
dpc-3558	100	46	analyzer	analyzer	NOUN
dpc-3558	100	47	(	(	PUNCT
dpc-3558	100	48	provean	provean	PROPN
dpc-3558	100	49	,	,	PUNCT
dpc-3558	100	50	http://provean.jcvi.org/index.php	http://provean.jcvi.org/index.php	NUM
dpc-3558	100	51	)	)	PUNCT
dpc-3558	100	52	,	,	PUNCT
dpc-3558	100	53	with	with	ADP
dpc-3558	100	54	a	a	DET
dpc-3558	100	55	score	score	NOUN
dpc-3558	100	56	of	of	ADP
dpc-3558	100	57	–	–	PUNCT
dpc-3558	100	58	6.872	6.872	NUM
dpc-3558	100	59	.	.	PUNCT
dpc-3558	101	1	the	the	DET
dpc-3558	101	2	pathogenicity	pathogenicity	NOUN
dpc-3558	101	3	of	of	ADP
dpc-3558	101	4	the	the	DET
dpc-3558	101	5	c.919c	c.919c	PROPN
dpc-3558	101	6	>	>	PROPN
dpc-3558	101	7	t;p.arg307trp	t;p.arg307trp	PROPN
dpc-3558	101	8	sequence	sequence	NOUN
dpc-3558	101	9	variant	variant	NOUN
dpc-3558	101	10	is	be	AUX
dpc-3558	101	11	also	also	ADV
dpc-3558	101	12	inferred	infer	VERB
dpc-3558	101	13	by	by	ADP
dpc-3558	101	14	its	its	PRON
dpc-3558	101	15	rarity	rarity	NOUN
dpc-3558	101	16	(	(	PUNCT
dpc-3558	101	17	prevalence	prevalence	NOUN
dpc-3558	101	18	in	in	ADP
dpc-3558	101	19	gnomad	gnomad	PROPN
dpc-3558	101	20	(	(	PUNCT
dpc-3558	101	21	https://gnomad.broadinstitute.org/	https://gnomad.broadinstitute.org/	NOUN
dpc-3558	101	22	)	)	PUNCT
dpc-3558	101	23	0.00002422	0.00002422	NUM
dpc-3558	101	24	with	with	ADP
dpc-3558	101	25	none	none	NOUN
dpc-3558	101	26	reported	report	VERB
dpc-3558	101	27	in	in	ADP
dpc-3558	101	28	brazilian	brazilian	ADJ
dpc-3558	101	29	databanks	databank	NOUN
dpc-3558	101	30	(	(	PUNCT
dpc-3558	101	31	https://abraom.ib.usp.br/	https://abraom.ib.usp.br/	PROPN
dpc-3558	101	32	)	)	PUNCT
dpc-3558	101	33	.	.	PUNCT
dpc-3558	102	1	variant	variant	ADJ
dpc-3558	102	2	classification	classification	NOUN
dpc-3558	102	3	according	accord	VERB
dpc-3558	102	4	to	to	ADP
dpc-3558	102	5	2015	2015	NUM
dpc-3558	102	6	acmg	acmg	NOUN
dpc-3558	102	7	guidelines	guideline	NOUN
dpc-3558	102	8	is	be	AUX
dpc-3558	102	9	pm2	pm2	NOUN
dpc-3558	102	10	(	(	PUNCT
dpc-3558	102	11	moderate	moderate	ADJ
dpc-3558	102	12	evidence	evidence	NOUN
dpc-3558	102	13	of	of	ADP
dpc-3558	102	14	pathogenicity	pathogenicity	NOUN
dpc-3558	102	15	)	)	PUNCT
dpc-3558	102	16	and	and	CCONJ
dpc-3558	102	17	with	with	ADP
dpc-3558	102	18	additional	additional	ADJ
dpc-3558	102	19	supporting	support	VERB
dpc-3558	102	20	evidence	evidence	NOUN
dpc-3558	102	21	of	of	ADP
dpc-3558	102	22	pathogenicity	pathogenicity	NOUN
dpc-3558	102	23	(	(	PUNCT
dpc-3558	102	24	pp1	pp1	NOUN
dpc-3558	102	25	)	)	PUNCT
dpc-3558	102	26	.	.	PUNCT
dpc-3558	103	1	immunohistochemistry	immunohistochemistry	NOUN
dpc-3558	103	2	analysis	analysis	NOUN
dpc-3558	103	3	demonstrated	demonstrate	VERB
dpc-3558	103	4	no	no	DET
dpc-3558	103	5	xpc	xpc	NOUN
dpc-3558	103	6	staining	stain	VERB
dpc-3558	103	7	in	in	ADP
dpc-3558	103	8	the	the	DET
dpc-3558	103	9	melanoma	melanoma	NOUN
dpc-3558	103	10	tissue	tissue	NOUN
dpc-3558	103	11	compared	compare	VERB
dpc-3558	103	12	with	with	ADP
dpc-3558	103	13	normal	normal	ADJ
dpc-3558	103	14	non	non	ADJ
dpc-3558	103	15	cancer	cancer	NOUN
dpc-3558	103	16	surrounding	surround	VERB
dpc-3558	103	17	dermal	dermal	ADJ
dpc-3558	103	18	tissue	tissue	NOUN
dpc-3558	103	19	,	,	PUNCT
dpc-3558	103	20	as	as	SCONJ
dpc-3558	103	21	is	be	AUX
dpc-3558	103	22	predicted	predict	VERB
dpc-3558	103	23	by	by	ADP
dpc-3558	103	24	functional	functional	ADJ
dpc-3558	103	25	studies	study	NOUN
dpc-3558	103	26	[	[	X
dpc-3558	103	27	9	9	NUM
dpc-3558	103	28	]	]	PUNCT
dpc-3558	103	29	(	(	PUNCT
dpc-3558	103	30	figure	figure	NOUN
dpc-3558	103	31	4	4	NUM
dpc-3558	103	32	)	)	PUNCT
dpc-3558	103	33	.	.	PUNCT
dpc-3558	104	1	conclusions	conclusion	NOUN
dpc-3558	104	2	xp	xp	INTJ
dpc-3558	104	3	is	be	AUX
dpc-3558	104	4	usually	usually	ADV
dpc-3558	104	5	diagnosed	diagnose	VERB
dpc-3558	104	6	in	in	ADP
dpc-3558	104	7	childhood	childhood	NOUN
dpc-3558	104	8	heralded	herald	VERB
dpc-3558	104	9	by	by	ADP
dpc-3558	104	10	the	the	DET
dpc-3558	104	11	presence	presence	NOUN
dpc-3558	104	12	of	of	ADP
dpc-3558	104	13	typical	typical	ADJ
dpc-3558	104	14	skin	skin	NOUN
dpc-3558	104	15	lesions	lesion	NOUN
dpc-3558	104	16	[	[	X
dpc-3558	104	17	5	5	NUM
dpc-3558	104	18	]	]	PUNCT
dpc-3558	104	19	.	.	PUNCT
dpc-3558	105	1	the	the	DET
dpc-3558	105	2	current	current	ADJ
dpc-3558	105	3	study	study	NOUN
dpc-3558	105	4	describes	describe	VERB
dpc-3558	105	5	figure	figure	NOUN
dpc-3558	105	6	4	4	NUM
dpc-3558	105	7	.	.	PUNCT
dpc-3558	105	8	immunohistochemistry	immunohistochemistry	NOUN
dpc-3558	105	9	assay	assay	PROPN
dpc-3558	105	10	.	.	PUNCT
dpc-3558	106	1	(	(	PUNCT
dpc-3558	106	2	a	a	X
dpc-3558	106	3	)	)	PUNCT
dpc-3558	106	4	melanoma	melanoma	NOUN
dpc-3558	106	5	tissue	tissue	NOUN
dpc-3558	106	6	from	from	ADP
dpc-3558	106	7	proband	proband	NOUN
dpc-3558	106	8	stained	stain	VERB
dpc-3558	106	9	with	with	ADP
dpc-3558	106	10	h&e	h&e	PROPN
dpc-3558	106	11	.	.	PUNCT
dpc-3558	107	1	(	(	PUNCT
dpc-3558	107	2	b	b	X
dpc-3558	107	3	)	)	PUNCT
dpc-3558	107	4	melanoma	melanoma	NOUN
dpc-3558	107	5	tissue	tissue	NOUN
dpc-3558	107	6	from	from	ADP
dpc-3558	107	7	proband	proband	NOUN
dpc-3558	107	8	very	very	ADV
dpc-3558	107	9	lightly	lightly	ADV
dpc-3558	107	10	stained	stain	VERB
dpc-3558	107	11	by	by	ADP
dpc-3558	107	12	the	the	DET
dpc-3558	107	13	xpc	xpc	PROPN
dpc-3558	107	14	antibody	antibody	NOUN
dpc-3558	107	15	,	,	PUNCT
dpc-3558	107	16	suggesting	suggest	VERB
dpc-3558	107	17	there	there	PRON
dpc-3558	107	18	is	be	VERB
dpc-3558	107	19	no	no	DET
dpc-3558	107	20	significant	significant	ADJ
dpc-3558	107	21	expression	expression	NOUN
dpc-3558	107	22	of	of	ADP
dpc-3558	107	23	this	this	DET
dpc-3558	107	24	protein	protein	NOUN
dpc-3558	107	25	in	in	ADP
dpc-3558	107	26	this	this	DET
dpc-3558	107	27	tissue	tissue	NOUN
dpc-3558	107	28	.	.	PUNCT
dpc-3558	108	1	the	the	DET
dpc-3558	108	2	dark	dark	ADJ
dpc-3558	108	3	color	color	NOUN
dpc-3558	108	4	is	be	AUX
dpc-3558	108	5	mostly	mostly	ADV
dpc-3558	108	6	due	due	ADJ
dpc-3558	108	7	to	to	ADP
dpc-3558	108	8	melanin	melanin	NOUN
dpc-3558	108	9	.	.	PUNCT
dpc-3558	109	1	(	(	PUNCT
dpc-3558	109	2	c	c	X
dpc-3558	109	3	)	)	PUNCT
dpc-3558	109	4	xpc	xpc	NOUN
dpc-3558	109	5	antibody	antibody	NOUN
dpc-3558	109	6	in	in	ADP
dpc-3558	109	7	a	a	DET
dpc-3558	109	8	control	control	NOUN
dpc-3558	109	9	tissue	tissue	NOUN
dpc-3558	109	10	(	(	PUNCT
dpc-3558	109	11	mucosa	mucosa	NOUN
dpc-3558	109	12	)	)	PUNCT
dpc-3558	109	13	showing	show	VERB
dpc-3558	109	14	high	high	ADJ
dpc-3558	109	15	positivity	positivity	NOUN
dpc-3558	109	16	,	,	PUNCT
dpc-3558	109	17	therefore	therefore	ADV
dpc-3558	109	18	,	,	PUNCT
dpc-3558	109	19	significant	significant	ADJ
dpc-3558	109	20	quantity	quantity	NOUN
dpc-3558	109	21	of	of	ADP
dpc-3558	109	22	xpc	xpc	NOUN
dpc-3558	109	23	protein	protein	NOUN
dpc-3558	109	24	in	in	ADP
dpc-3558	109	25	this	this	DET
dpc-3558	109	26	normal	normal	ADJ
dpc-3558	109	27	tissue	tissue	NOUN
dpc-3558	109	28	.	.	PUNCT
dpc-3558	110	1	(	(	PUNCT
dpc-3558	110	2	d	d	X
dpc-3558	110	3	)	)	PUNCT
dpc-3558	110	4	the	the	DET
dpc-3558	110	5	same	same	ADJ
dpc-3558	110	6	melanoma	melanoma	NOUN
dpc-3558	110	7	tissue	tissue	NOUN
dpc-3558	110	8	from	from	ADP
dpc-3558	110	9	proband	proband	NOUN
dpc-3558	110	10	highly	highly	ADV
dpc-3558	110	11	colored	color	VERB
dpc-3558	110	12	by	by	ADP
dpc-3558	110	13	a	a	DET
dpc-3558	110	14	control	control	NOUN
dpc-3558	110	15	anti	anti	ADJ
dpc-3558	110	16	-	-	ADJ
dpc-3558	110	17	tubulin	tubulin	ADJ
dpc-3558	110	18	antibody	antibody	NOUN
dpc-3558	110	19	,	,	PUNCT
dpc-3558	110	20	showing	show	VERB
dpc-3558	110	21	that	that	SCONJ
dpc-3558	110	22	this	this	DET
dpc-3558	110	23	tissue	tissue	NOUN
dpc-3558	110	24	is	be	AUX
dpc-3558	110	25	indeed	indeed	ADV
dpc-3558	110	26	viable	viable	ADJ
dpc-3558	110	27	.	.	PUNCT
dpc-3558	111	1	6	6	NUM
dpc-3558	111	2	original	original	ADJ
dpc-3558	111	3	article	article	NOUN
dpc-3558	111	4	|	|	ADV
dpc-3558	111	5	dermatol	dermatol	ADJ
dpc-3558	111	6	pract	pract	NOUN
dpc-3558	111	7	concept	concept	NOUN
dpc-3558	111	8	.	.	PUNCT
dpc-3558	112	1	2024;14(1):e2024050	2024;14(1):e2024050	NUM
dpc-3558	113	1	3	3	NUM
dpc-3558	113	2	.	.	PUNCT
dpc-3558	113	3	ali	ali	PROPN
dpc-3558	113	4	mz	mz	PROPN
dpc-3558	113	5	,	,	PUNCT
dpc-3558	113	6	blatterer	blatterer	PROPN
dpc-3558	113	7	j	j	PROPN
dpc-3558	113	8	,	,	PUNCT
dpc-3558	113	9	khan	khan	PROPN
dpc-3558	113	10	ma	ma	PROPN
dpc-3558	113	11	,	,	PUNCT
dpc-3558	113	12	et	et	PROPN
dpc-3558	113	13	al	al	PROPN
dpc-3558	113	14	.	.	PUNCT
dpc-3558	113	15	identification	identification	NOUN
dpc-3558	113	16	of	of	ADP
dpc-3558	113	17	a	a	DET
dpc-3558	113	18	novel	novel	ADJ
dpc-3558	113	19	protein	protein	NOUN
dpc-3558	113	20	truncating	truncate	VERB
dpc-3558	113	21	mutation	mutation	NOUN
dpc-3558	113	22	p.asp98	p.asp98	NOUN
dpc-3558	113	23	*	*	PUNCT
dpc-3558	113	24	in	in	ADP
dpc-3558	113	25	xpc	xpc	PROPN
dpc-3558	113	26	associated	associate	VERB
dpc-3558	113	27	with	with	ADP
dpc-3558	113	28	xeroderma	xeroderma	PROPN
dpc-3558	113	29	pigmentosum	pigmentosum	PROPN
dpc-3558	113	30	in	in	ADP
dpc-3558	113	31	a	a	DET
dpc-3558	113	32	consanguineous	consanguineous	ADJ
dpc-3558	113	33	pakistani	pakistani	ADJ
dpc-3558	113	34	family	family	NOUN
dpc-3558	113	35	.	.	PUNCT
dpc-3558	114	1	mol	mol	ADP
dpc-3558	114	2	genet	genet	PROPN
dpc-3558	114	3	genomic	genomic	PROPN
dpc-3558	114	4	med	med	PROPN
dpc-3558	114	5	.	.	PUNCT
dpc-3558	115	1	2020;8(2):e1060	2020;8(2):e1060	PROPN
dpc-3558	115	2	.	.	PUNCT
dpc-3558	116	1	doi	doi	PROPN
dpc-3558	116	2	:	:	PUNCT
dpc-3558	116	3	10.1002	10.1002	NUM
dpc-3558	116	4	/mgg3.1060	/mgg3.1060	NOUN
dpc-3558	116	5	.	.	PUNCT
dpc-3558	117	1	pmid	pmid	NOUN
dpc-3558	117	2	:	:	PUNCT
dpc-3558	117	3	31923348	31923348	NUM
dpc-3558	117	4	.	.	PUNCT
dpc-3558	118	1	pmcid	pmcid	NOUN
dpc-3558	118	2	:	:	PUNCT
dpc-3558	118	3	pmc7005610	pmc7005610	ADJ
dpc-3558	118	4	.	.	PUNCT
dpc-3558	119	1	4	4	X
dpc-3558	119	2	.	.	X
dpc-3558	119	3	meneses	menese	NOUN
dpc-3558	119	4	m	m	PROPN
dpc-3558	119	5	,	,	PUNCT
dpc-3558	119	6	chavez	chavez	PROPN
dpc-3558	119	7	-	-	PUNCT
dpc-3558	119	8	bourgeois	bourgeois	PROPN
dpc-3558	119	9	m	m	PROPN
dpc-3558	119	10	,	,	PUNCT
dpc-3558	119	11	badenas	badenas	PROPN
dpc-3558	119	12	c	c	AUX
dpc-3558	119	13	,	,	PUNCT
dpc-3558	119	14	et	et	PROPN
dpc-3558	119	15	al	al	PROPN
dpc-3558	119	16	.	.	PUNCT
dpc-3558	120	1	atypical	atypical	ADJ
dpc-3558	120	2	clinical	clinical	ADJ
dpc-3558	120	3	presentation	presentation	NOUN
dpc-3558	120	4	of	of	ADP
dpc-3558	120	5	xeroderma	xeroderma	PROPN
dpc-3558	120	6	pigmentosum	pigmentosum	PROPN
dpc-3558	120	7	in	in	ADP
dpc-3558	120	8	a	a	DET
dpc-3558	120	9	patient	patient	NOUN
dpc-3558	120	10	harboring	harbor	VERB
dpc-3558	120	11	a	a	DET
dpc-3558	120	12	novel	novel	ADJ
dpc-3558	120	13	missense	missense	NOUN
dpc-3558	120	14	mutation	mutation	NOUN
dpc-3558	120	15	in	in	ADP
dpc-3558	120	16	the	the	DET
dpc-3558	120	17	xpc	xpc	PROPN
dpc-3558	120	18	gene	gene	NOUN
dpc-3558	120	19	:	:	PUNCT
dpc-3558	120	20	the	the	DET
dpc-3558	120	21	importance	importance	NOUN
dpc-3558	120	22	of	of	ADP
dpc-3558	120	23	clinical	clinical	ADJ
dpc-3558	120	24	suspicion	suspicion	NOUN
dpc-3558	120	25	.	.	PUNCT
dpc-3558	121	1	dermatology	dermatology	NOUN
dpc-3558	121	2	.	.	PUNCT
dpc-3558	122	1	2015;231(3	2015;231(3	NUM
dpc-3558	122	2	):	):	PUNCT
dpc-3558	122	3	217	217	NUM
dpc-3558	122	4	-	-	SYM
dpc-3558	122	5	221	221	NUM
dpc-3558	122	6	.	.	PUNCT
dpc-3558	123	1	doi	doi	NOUN
dpc-3558	123	2	:	:	PUNCT
dpc-3558	123	3	10.1159/000433527	10.1159/000433527	NUM
dpc-3558	123	4	.	.	PUNCT
dpc-3558	124	1	pmid	pmid	NOUN
dpc-3558	124	2	:	:	PUNCT
dpc-3558	124	3	26278556	26278556	NUM
dpc-3558	124	4	.	.	PUNCT
dpc-3558	125	1	5	5	X
dpc-3558	125	2	.	.	X
dpc-3558	125	3	ribeiro	ribeiro	PROPN
dpc-3558	125	4	mg	mg	PROPN
dpc-3558	125	5	,	,	PUNCT
dpc-3558	125	6	zunta	zunta	PROPN
dpc-3558	125	7	gl	gl	PROPN
dpc-3558	125	8	,	,	PUNCT
dpc-3558	125	9	santos	santos	PROPN
dpc-3558	125	10	js	js	PROPN
dpc-3558	125	11	,	,	PUNCT
dpc-3558	125	12	moraes	moraes	PROPN
dpc-3558	125	13	am	be	AUX
dpc-3558	125	14	,	,	PUNCT
dpc-3558	125	15	lima	lima	PROPN
dpc-3558	125	16	csp	csp	PROPN
dpc-3558	125	17	,	,	PUNCT
dpc-3558	125	18	ortega	ortega	PROPN
dpc-3558	125	19	mm	mm	PROPN
dpc-3558	125	20	.	.	PUNCT
dpc-3558	126	1	clinical	clinical	ADJ
dpc-3558	126	2	features	feature	NOUN
dpc-3558	126	3	related	relate	VERB
dpc-3558	126	4	to	to	ADP
dpc-3558	126	5	xeroderma	xeroderma	PROPN
dpc-3558	126	6	pigmentosum	pigmentosum	PROPN
dpc-3558	126	7	in	in	ADP
dpc-3558	126	8	a	a	DET
dpc-3558	126	9	brazilian	brazilian	ADJ
dpc-3558	126	10	patient	patient	NOUN
dpc-3558	126	11	diagnosed	diagnose	VERB
dpc-3558	126	12	at	at	ADP
dpc-3558	126	13	advanced	advanced	ADJ
dpc-3558	126	14	age	age	NOUN
dpc-3558	126	15	.	.	PUNCT
dpc-3558	127	1	appl	appl	PROPN
dpc-3558	127	2	clin	clin	PROPN
dpc-3558	127	3	genet	genet	PROPN
dpc-3558	127	4	.	.	PUNCT
dpc-3558	128	1	2018;11:89	2018;11:89	X
dpc-3558	128	2	-	-	SYM
dpc-3558	128	3	92	92	NUM
dpc-3558	128	4	.	.	PUNCT
dpc-3558	129	1	doi	doi	NOUN
dpc-3558	129	2	:	:	PUNCT
dpc-3558	129	3	10.2147	10.2147	NUM
dpc-3558	129	4	/	/	SYM
dpc-3558	129	5	tacg.s155083	tacg.s155083	NOUN
dpc-3558	129	6	.	.	PUNCT
dpc-3558	130	1	pmid	pmid	NOUN
dpc-3558	130	2	:	:	PUNCT
dpc-3558	130	3	30127633	30127633	NUM
dpc-3558	130	4	.	.	PUNCT
dpc-3558	131	1	pmcid	pmcid	NOUN
dpc-3558	131	2	:	:	PUNCT
dpc-3558	131	3	pmc6089094	pmc6089094	NOUN
dpc-3558	131	4	.	.	PUNCT
dpc-3558	132	1	6	6	X
dpc-3558	132	2	.	.	X
dpc-3558	132	3	sá	sá	PROPN
dpc-3558	132	4	bcs	bcs	PROPN
dpc-3558	132	5	,	,	PUNCT
dpc-3558	132	6	moredo	moredo	PROPN
dpc-3558	132	7	lf	lf	PROPN
dpc-3558	132	8	,	,	PUNCT
dpc-3558	132	9	gomes	gomes	PROPN
dpc-3558	132	10	ee	ee	PROPN
dpc-3558	132	11	,	,	PUNCT
dpc-3558	132	12	araújo	araújo	PROPN
dpc-3558	132	13	ess	ess	PROPN
dpc-3558	132	14	,	,	PUNCT
dpc-3558	132	15	duprat	duprat	NOUN
dpc-3558	132	16	jp	jp	PROPN
dpc-3558	132	17	.	.	PUNCT
dpc-3558	133	1	hereditary	hereditary	ADJ
dpc-3558	133	2	melanoma	melanoma	NOUN
dpc-3558	133	3	:	:	PUNCT
dpc-3558	133	4	a	a	DET
dpc-3558	133	5	five	five	NUM
dpc-3558	133	6	-	-	PUNCT
dpc-3558	133	7	year	year	NOUN
dpc-3558	133	8	study	study	NOUN
dpc-3558	133	9	of	of	ADP
dpc-3558	133	10	brazilian	brazilian	ADJ
dpc-3558	133	11	patients	patient	NOUN
dpc-3558	133	12	in	in	ADP
dpc-3558	133	13	a	a	DET
dpc-3558	133	14	cancer	cancer	NOUN
dpc-3558	133	15	referral	referral	NOUN
dpc-3558	133	16	center	center	NOUN
dpc-3558	133	17	phenotypic	phenotypic	ADJ
dpc-3558	133	18	characteristics	characteristic	NOUN
dpc-3558	133	19	of	of	ADP
dpc-3558	133	20	probands	proband	NOUN
dpc-3558	133	21	and	and	CCONJ
dpc-3558	133	22	pathological	pathological	ADJ
dpc-3558	133	23	features	feature	NOUN
dpc-3558	133	24	of	of	ADP
dpc-3558	133	25	primary	primary	ADJ
dpc-3558	133	26	tumors	tumor	NOUN
dpc-3558	133	27	.	.	PUNCT
dpc-3558	134	1	an	an	DET
dpc-3558	134	2	bras	bras	NOUN
dpc-3558	134	3	dermatol	dermatol	NOUN
dpc-3558	134	4	.	.	PUNCT
dpc-3558	135	1	2018;93(3):337	2018;93(3):337	NOUN
dpc-3558	135	2	-	-	PUNCT
dpc-3558	135	3	340	340	NUM
dpc-3558	135	4	.	.	PUNCT
dpc-3558	136	1	doi	doi	NOUN
dpc-3558	136	2	:	:	PUNCT
dpc-3558	136	3	10.1590	10.1590	NUM
dpc-3558	136	4	/	/	SYM
dpc-3558	136	5	abd1806	abd1806	NOUN
dpc-3558	136	6	-	-	PUNCT
dpc-3558	136	7	4841.20186201	4841.20186201	NOUN
dpc-3558	136	8	.	.	PUNCT
dpc-3558	137	1	pmid	pmid	NOUN
dpc-3558	137	2	:	:	PUNCT
dpc-3558	137	3	29924249	29924249	NUM
dpc-3558	137	4	.	.	PUNCT
dpc-3558	138	1	pmcid	pmcid	NOUN
dpc-3558	138	2	:	:	PUNCT
dpc-3558	138	3	pmc6001076	pmc6001076	ADJ
dpc-3558	138	4	.	.	PUNCT
dpc-3558	139	1	7	7	X
dpc-3558	139	2	.	.	X
dpc-3558	139	3	abdo	abdo	PROPN
dpc-3558	139	4	jf	jf	PROPN
dpc-3558	139	5	,	,	PUNCT
dpc-3558	139	6	sharma	sharma	PROPN
dpc-3558	139	7	a	a	PROPN
dpc-3558	139	8	,	,	PUNCT
dpc-3558	139	9	sharma	sharma	PROPN
dpc-3558	139	10	r.	r.	PROPN
dpc-3558	139	11	role	role	NOUN
dpc-3558	139	12	of	of	ADP
dpc-3558	139	13	heredity	heredity	NOUN
dpc-3558	139	14	in	in	ADP
dpc-3558	139	15	melanoma	melanoma	NOUN
dpc-3558	139	16	susceptibility	susceptibility	NOUN
dpc-3558	139	17	:	:	PUNCT
dpc-3558	139	18	a	a	DET
dpc-3558	139	19	primer	primer	NOUN
dpc-3558	139	20	for	for	ADP
dpc-3558	139	21	the	the	DET
dpc-3558	139	22	practicing	practice	VERB
dpc-3558	139	23	surgeon	surgeon	NOUN
dpc-3558	139	24	.	.	PUNCT
dpc-3558	140	1	surg	surg	PROPN
dpc-3558	140	2	clin	clin	PROPN
dpc-3558	140	3	north	north	PROPN
dpc-3558	140	4	am	am	PROPN
dpc-3558	140	5	.	.	PUNCT
dpc-3558	141	1	2020;100(1):13	2020;100(1):13	NUM
dpc-3558	141	2	-	-	SYM
dpc-3558	141	3	28	28	NUM
dpc-3558	141	4	.	.	PUNCT
dpc-3558	142	1	doi	doi	NOUN
dpc-3558	142	2	:	:	PUNCT
dpc-3558	142	3	10.1016	10.1016	NUM
dpc-3558	142	4	/	/	SYM
dpc-3558	142	5	j.suc	j.suc	PROPN
dpc-3558	142	6	.2019.09.006	.2019.09.006	PROPN
dpc-3558	142	7	.	.	PUNCT
dpc-3558	143	1	pmid	pmid	NOUN
dpc-3558	143	2	:	:	PUNCT
dpc-3558	143	3	31753108	31753108	NUM
dpc-3558	143	4	.	.	PUNCT
dpc-3558	144	1	8	8	X
dpc-3558	144	2	.	.	PUNCT
dpc-3558	145	1	g	g	NOUN
dpc-3558	145	2	c	c	PROPN
dpc-3558	145	3	c	c	PROPN
dpc-3558	145	4	l	l	PROPN
dpc-3558	145	5	cardenas	cardenas	PROPN
dpc-3558	145	6	r	r	PROPN
dpc-3558	145	7	,	,	PUNCT
dpc-3558	145	8	d	d	PROPN
dpc-3558	145	9	linhares	linhare	NOUN
dpc-3558	145	10	n	n	CCONJ
dpc-3558	145	11	,	,	PUNCT
dpc-3558	145	12	l	l	PROPN
dpc-3558	145	13	ferreira	ferreira	PROPN
dpc-3558	145	14	r	r	PROPN
dpc-3558	145	15	,	,	PUNCT
dpc-3558	145	16	pena	pena	PROPN
dpc-3558	145	17	sdj	sdj	PROPN
dpc-3558	145	18	.	.	PUNCT
dpc-3558	146	1	mendel	mendel	PROPN
dpc-3558	146	2	,	,	PUNCT
dpc-3558	146	3	md	md	PROPN
dpc-3558	146	4	:	:	PUNCT
dpc-3558	146	5	a	a	DET
dpc-3558	146	6	user	user	NOUN
dpc-3558	146	7	-	-	PUNCT
dpc-3558	146	8	friendly	friendly	ADJ
dpc-3558	146	9	open	open	ADJ
dpc-3558	146	10	-	-	PUNCT
dpc-3558	146	11	source	source	NOUN
dpc-3558	146	12	web	web	NOUN
dpc-3558	146	13	tool	tool	NOUN
dpc-3558	146	14	for	for	ADP
dpc-3558	146	15	analyzing	analyze	VERB
dpc-3558	146	16	wes	wes	PROPN
dpc-3558	146	17	and	and	CCONJ
dpc-3558	146	18	wgs	wgs	NOUN
dpc-3558	146	19	in	in	ADP
dpc-3558	146	20	the	the	DET
dpc-3558	146	21	diagnosis	diagnosis	NOUN
dpc-3558	146	22	of	of	ADP
dpc-3558	146	23	patients	patient	NOUN
dpc-3558	146	24	with	with	ADP
dpc-3558	146	25	mendelian	mendelian	ADJ
dpc-3558	146	26	disorders	disorder	NOUN
dpc-3558	146	27	.	.	PUNCT
dpc-3558	147	1	plos	plos	PROPN
dpc-3558	147	2	comput	comput	PROPN
dpc-3558	147	3	biol	biol	PROPN
dpc-3558	147	4	.	.	PUNCT
dpc-3558	148	1	2017;13(6):e1005520	2017;13(6):e1005520	X
dpc-3558	148	2	.	.	PUNCT
dpc-3558	149	1	doi	doi	NOUN
dpc-3558	149	2	:	:	PUNCT
dpc-3558	149	3	10.1371	10.1371	NUM
dpc-3558	149	4	/	/	SYM
dpc-3558	149	5	journal.pcbi.1005520	journal.pcbi.1005520	PROPN
dpc-3558	149	6	.	.	PUNCT
dpc-3558	150	1	pmid	pmid	PROPN
dpc-3558	150	2	:	:	PUNCT
dpc-3558	150	3	28594829	28594829	NUM
dpc-3558	150	4	.	.	PUNCT
dpc-3558	151	1	pmcid	pmcid	NOUN
dpc-3558	151	2	:	:	PUNCT
dpc-3558	151	3	pmc5464533	pmc5464533	NOUN
dpc-3558	151	4	.	.	PUNCT
dpc-3558	152	1	9	9	X
dpc-3558	152	2	.	.	X
dpc-3558	152	3	budden	budden	PROPN
dpc-3558	152	4	t	t	PROPN
dpc-3558	152	5	,	,	PUNCT
dpc-3558	152	6	davey	davey	PROPN
dpc-3558	152	7	rj	rj	PROPN
dpc-3558	152	8	,	,	PUNCT
dpc-3558	152	9	vilain	vilain	VERB
dpc-3558	152	10	re	re	PROPN
dpc-3558	152	11	,	,	PUNCT
dpc-3558	152	12	et	et	PROPN
dpc-3558	152	13	al	al	PROPN
dpc-3558	152	14	.	.	PROPN
dpc-3558	152	15	repair	repair	NOUN
dpc-3558	152	16	of	of	ADP
dpc-3558	152	17	uvb	uvb	ADJ
dpc-3558	152	18	-	-	ADJ
dpc-3558	152	19	induced	induced	ADJ
dpc-3558	152	20	dna	dna	PROPN
dpc-3558	152	21	damage	damage	NOUN
dpc-3558	152	22	is	be	AUX
dpc-3558	152	23	reduced	reduce	VERB
dpc-3558	152	24	in	in	ADP
dpc-3558	152	25	melanoma	melanoma	NOUN
dpc-3558	152	26	due	due	ADP
dpc-3558	152	27	to	to	ADP
dpc-3558	152	28	low	low	ADJ
dpc-3558	152	29	xpc	xpc	PROPN
dpc-3558	152	30	and	and	CCONJ
dpc-3558	152	31	global	global	ADJ
dpc-3558	152	32	genome	genome	NOUN
dpc-3558	152	33	repair	repair	NOUN
dpc-3558	152	34	.	.	PUNCT
dpc-3558	153	1	oncotarget	oncotarget	NOUN
dpc-3558	153	2	.	.	PUNCT
dpc-3558	154	1	2016;7(38):60940	2016;7(38):60940	NUM
dpc-3558	154	2	-	-	SYM
dpc-3558	154	3	60953	60953	NUM
dpc-3558	154	4	.	.	PUNCT
dpc-3558	155	1	doi	doi	NOUN
dpc-3558	155	2	:	:	PUNCT
dpc-3558	155	3	10.18632	10.18632	NUM
dpc-3558	155	4	/	/	SYM
dpc-3558	155	5	oncotarget.10902	oncotarget.10902	PROPN
dpc-3558	155	6	.	.	PUNCT
dpc-3558	156	1	pmid	pmid	NOUN
dpc-3558	156	2	:	:	PUNCT
dpc-3558	156	3	27487145	27487145	NUM
dpc-3558	156	4	.	.	PUNCT
dpc-3558	157	1	pmcid	pmcid	NOUN
dpc-3558	157	2	:	:	PUNCT
dpc-3558	157	3	pmc5308628	pmc5308628	NOUN
dpc-3558	157	4	.	.	PUNCT
dpc-3558	158	1	10	10	NUM
dpc-3558	158	2	.	.	PUNCT
dpc-3558	159	1	fassihi	fassihi	PROPN
dpc-3558	159	2	h	h	PROPN
dpc-3558	159	3	,	,	PUNCT
dpc-3558	159	4	sethi	sethi	PROPN
dpc-3558	159	5	m	m	PROPN
dpc-3558	159	6	,	,	PUNCT
dpc-3558	159	7	fawcett	fawcett	PROPN
dpc-3558	159	8	h	h	PROPN
dpc-3558	159	9	,	,	PUNCT
dpc-3558	159	10	et	et	PROPN
dpc-3558	159	11	al	al	PROPN
dpc-3558	159	12	.	.	PUNCT
dpc-3558	160	1	deep	deep	ADJ
dpc-3558	160	2	phenotyping	phenotyping	NOUN
dpc-3558	160	3	of	of	ADP
dpc-3558	160	4	89	89	NUM
dpc-3558	160	5	xeroderma	xeroderma	NOUN
dpc-3558	160	6	pigmentosum	pigmentosum	NOUN
dpc-3558	160	7	patients	patient	NOUN
dpc-3558	160	8	reveals	reveal	VERB
dpc-3558	160	9	unexpected	unexpected	ADJ
dpc-3558	160	10	heterogeneity	heterogeneity	NOUN
dpc-3558	160	11	dependent	dependent	ADJ
dpc-3558	160	12	on	on	ADP
dpc-3558	160	13	the	the	DET
dpc-3558	160	14	precise	precise	ADJ
dpc-3558	160	15	molecular	molecular	ADJ
dpc-3558	160	16	defect	defect	NOUN
dpc-3558	160	17	.	.	PUNCT
dpc-3558	161	1	proc	proc	PROPN
dpc-3558	161	2	natl	natl	PROPN
dpc-3558	161	3	acad	acad	PROPN
dpc-3558	161	4	sci	sci	PROPN
dpc-3558	161	5	u	u	PROPN
dpc-3558	161	6	s	s	PROPN
dpc-3558	161	7	a.	a.	NOUN
dpc-3558	161	8	2016	2016	NUM
dpc-3558	161	9	1;113(9):e1236e1245	1;113(9):e1236e1245	PROPN
dpc-3558	161	10	.	.	PUNCT
dpc-3558	162	1	doi	doi	NOUN
dpc-3558	162	2	:	:	PUNCT
dpc-3558	162	3	10.1073	10.1073	NUM
dpc-3558	162	4	/pnas.1519444113	/pnas.1519444113	X
dpc-3558	162	5	.	.	PUNCT
dpc-3558	163	1	pmid	pmid	NOUN
dpc-3558	163	2	:	:	PUNCT
dpc-3558	163	3	26884178	26884178	NUM
dpc-3558	163	4	.	.	PUNCT
dpc-3558	164	1	pmcid	pmcid	ADJ
dpc-3558	164	2	:	:	PUNCT
dpc-3558	164	3	pmc4780618	pmc4780618	NOUN
dpc-3558	164	4	.	.	PUNCT
dpc-3558	165	1	11	11	NUM
dpc-3558	165	2	.	.	PUNCT
dpc-3558	166	1	macke	macke	PROPN
dpc-3558	166	2	el	el	PROPN
dpc-3558	166	3	,	,	PUNCT
dpc-3558	166	4	morales	morale	NOUN
dpc-3558	166	5	-	-	PUNCT
dpc-3558	166	6	rosado	rosado	NOUN
dpc-3558	166	7	ja	ja	PROPN
dpc-3558	166	8	,	,	PUNCT
dpc-3558	166	9	gupta	gupta	PROPN
dpc-3558	166	10	a	a	PRON
dpc-3558	166	11	,	,	PUNCT
dpc-3558	166	12	et	et	PROPN
dpc-3558	166	13	al	al	PROPN
dpc-3558	166	14	.	.	PUNCT
dpc-3558	167	1	a	a	DET
dpc-3558	167	2	novel	novel	ADJ
dpc-3558	167	3	missense	missense	NOUN
dpc-3558	167	4	variant	variant	NOUN
dpc-3558	167	5	and	and	CCONJ
dpc-3558	167	6	multiexon	multiexon	ADJ
dpc-3558	167	7	deletion	deletion	NOUN
dpc-3558	167	8	causing	cause	VERB
dpc-3558	167	9	a	a	DET
dpc-3558	167	10	delayed	delayed	ADJ
dpc-3558	167	11	presentation	presentation	NOUN
dpc-3558	167	12	of	of	ADP
dpc-3558	167	13	xeroderma	xeroderma	PROPN
dpc-3558	167	14	pigmentosum	pigmentosum	PROPN
dpc-3558	167	15	,	,	PUNCT
dpc-3558	167	16	group	group	NOUN
dpc-3558	167	17	c.	c.	PROPN
dpc-3558	167	18	cold	cold	PROPN
dpc-3558	167	19	spring	spring	PROPN
dpc-3558	167	20	harb	harb	PROPN
dpc-3558	167	21	mol	mol	ADP
dpc-3558	167	22	case	case	NOUN
dpc-3558	167	23	stud	stud	NOUN
dpc-3558	167	24	.	.	PUNCT
dpc-3558	168	1	2020;6(4):a005165	2020;6(4):a005165	NOUN
dpc-3558	168	2	.	.	PUNCT
dpc-3558	169	1	doi	doi	NOUN
dpc-3558	169	2	:	:	PUNCT
dpc-3558	169	3	10.1101	10.1101	NUM
dpc-3558	169	4	/	/	SYM
dpc-3558	169	5	mcs.a005165	mcs.a005165	NOUN
dpc-3558	169	6	.	.	PUNCT
dpc-3558	170	1	pmid	pmid	NOUN
dpc-3558	170	2	:	:	PUNCT
dpc-3558	170	3	32843428	32843428	NUM
dpc-3558	170	4	.	.	PUNCT
dpc-3558	171	1	pmcid	pmcid	NOUN
dpc-3558	171	2	:	:	PUNCT
dpc-3558	171	3	pmc7476405	pmc7476405	PROPN
dpc-3558	171	4	.	.	PUNCT
dpc-3558	172	1	12	12	NUM
dpc-3558	172	2	.	.	PUNCT
dpc-3558	173	1	jacobelli	jacobelli	PROPN
dpc-3558	173	2	s	s	PROPN
dpc-3558	173	3	,	,	PUNCT
dpc-3558	173	4	soufir	soufir	NOUN
dpc-3558	173	5	n	n	CCONJ
dpc-3558	173	6	,	,	PUNCT
dpc-3558	173	7	lacapere	lacapere	PROPN
dpc-3558	173	8	jj	jj	PROPN
dpc-3558	173	9	,	,	PUNCT
dpc-3558	173	10	et	et	PROPN
dpc-3558	173	11	al	al	PROPN
dpc-3558	173	12	.	.	PROPN
dpc-3558	173	13	xeroderma	xeroderma	PROPN
dpc-3558	173	14	pigmentosum	pigmentosum	PROPN
dpc-3558	173	15	group	group	PROPN
dpc-3558	173	16	c	c	PROPN
dpc-3558	173	17	in	in	ADP
dpc-3558	173	18	a	a	DET
dpc-3558	173	19	french	french	ADJ
dpc-3558	173	20	caucasian	caucasian	ADJ
dpc-3558	173	21	patient	patient	NOUN
dpc-3558	173	22	with	with	ADP
dpc-3558	173	23	multiple	multiple	ADJ
dpc-3558	173	24	melanoma	melanoma	NOUN
dpc-3558	173	25	and	and	CCONJ
dpc-3558	173	26	unusual	unusual	ADJ
dpc-3558	173	27	long	long	ADJ
dpc-3558	173	28	-	-	PUNCT
dpc-3558	173	29	term	term	NOUN
dpc-3558	173	30	survival	survival	NOUN
dpc-3558	173	31	.	.	PUNCT
dpc-3558	174	1	br	br	PROPN
dpc-3558	174	2	j	j	PROPN
dpc-3558	174	3	dermatol	dermatol	NOUN
dpc-3558	174	4	.	.	PUNCT
dpc-3558	175	1	2008;159(4	2008;159(4	NUM
dpc-3558	175	2	):	):	PUNCT
dpc-3558	175	3	968	968	NUM
dpc-3558	175	4	-	-	SYM
dpc-3558	175	5	973	973	NUM
dpc-3558	175	6	.	.	PUNCT
dpc-3558	176	1	doi	doi	NOUN
dpc-3558	176	2	:	:	PUNCT
dpc-3558	176	3	10.1111	10.1111	NUM
dpc-3558	176	4	/	/	SYM
dpc-3558	176	5	j.1365	j.1365	NOUN
dpc-3558	176	6	-	-	PUNCT
dpc-3558	176	7	2133.2008.08791.x	2133.2008.08791.x	NUM
dpc-3558	176	8	.	.	PUNCT
dpc-3558	177	1	pmid	pmid	NOUN
dpc-3558	177	2	:	:	PUNCT
dpc-3558	177	3	18717677	18717677	NUM
dpc-3558	177	4	.	.	PUNCT
dpc-3558	178	1	diagnosed	diagnose	VERB
dpc-3558	178	2	in	in	ADP
dpc-3558	178	3	chronically	chronically	ADV
dpc-3558	178	4	sun	sun	NOUN
dpc-3558	178	5	exposed	expose	VERB
dpc-3558	178	6	areas	area	NOUN
dpc-3558	178	7	,	,	PUNCT
dpc-3558	178	8	such	such	ADJ
dpc-3558	178	9	as	as	ADP
dpc-3558	178	10	scalp	scalp	NOUN
dpc-3558	178	11	of	of	ADP
dpc-3558	178	12	hairy	hairy	ADJ
dpc-3558	178	13	individuals	individual	NOUN
dpc-3558	178	14	,	,	PUNCT
dpc-3558	178	15	lack	lack	NOUN
dpc-3558	178	16	of	of	ADP
dpc-3558	178	17	typical	typical	ADJ
dpc-3558	178	18	xp	xp	ADV
dpc-3558	178	19	-	-	PUNCT
dpc-3558	178	20	associated	associate	VERB
dpc-3558	178	21	skin	skin	NOUN
dpc-3558	178	22	changes	change	NOUN
dpc-3558	178	23	such	such	ADJ
dpc-3558	178	24	as	as	ADP
dpc-3558	178	25	actinic	actinic	ADJ
dpc-3558	178	26	keratosis	keratosis	NOUN
dpc-3558	178	27	,	,	PUNCT
dpc-3558	178	28	atrophy	atrophy	NOUN
dpc-3558	178	29	,	,	PUNCT
dpc-3558	178	30	telangiectasias	telangiectasia	NOUN
dpc-3558	178	31	and	and	CCONJ
dpc-3558	178	32	marked	mark	VERB
dpc-3558	178	33	skin	skin	NOUN
dpc-3558	178	34	photoaging	photoaging	NOUN
dpc-3558	178	35	.	.	PUNCT
dpc-3558	179	1	in	in	ADP
dpc-3558	179	2	the	the	DET
dpc-3558	179	3	present	present	ADJ
dpc-3558	179	4	study	study	NOUN
dpc-3558	179	5	,	,	PUNCT
dpc-3558	179	6	having	have	VERB
dpc-3558	179	7	both	both	CCONJ
dpc-3558	179	8	the	the	DET
dpc-3558	179	9	xpc	xpc	PROPN
dpc-3558	179	10	homozygous	homozygous	ADJ
dpc-3558	179	11	variant	variant	NOUN
dpc-3558	179	12	and	and	CCONJ
dpc-3558	179	13	a	a	DET
dpc-3558	179	14	variant	variant	ADJ
dpc-3558	179	15	mc1r	mc1r	NOUN
dpc-3558	179	16	allele	allele	NOUN
dpc-3558	179	17	(	(	PUNCT
dpc-3558	179	18	p.i155	p.i155	PROPN
dpc-3558	179	19	t	t	PROPN
dpc-3558	179	20	)	)	PUNCT
dpc-3558	179	21	may	may	AUX
dpc-3558	179	22	have	have	AUX
dpc-3558	179	23	deleteriously	deleteriously	ADV
dpc-3558	179	24	affected	affect	VERB
dpc-3558	179	25	the	the	DET
dpc-3558	179	26	phenotype	phenotype	NOUN
dpc-3558	179	27	,	,	PUNCT
dpc-3558	179	28	with	with	ADP
dpc-3558	179	29	those	those	PRON
dpc-3558	179	30	harboring	harbor	VERB
dpc-3558	179	31	both	both	DET
dpc-3558	179	32	variants	variant	NOUN
dpc-3558	179	33	exhibiting	exhibit	VERB
dpc-3558	179	34	seemingly	seemingly	ADV
dpc-3558	179	35	a	a	DET
dpc-3558	179	36	more	more	ADV
dpc-3558	179	37	aggressive	aggressive	ADJ
dpc-3558	179	38	clinical	clinical	ADJ
dpc-3558	179	39	and	and	CCONJ
dpc-3558	179	40	pathological	pathological	ADJ
dpc-3558	179	41	phenotype	phenotype	NOUN
dpc-3558	179	42	.	.	PUNCT
dpc-3558	180	1	few	few	ADJ
dpc-3558	180	2	studies	study	NOUN
dpc-3558	180	3	reported	report	VERB
dpc-3558	180	4	the	the	DET
dpc-3558	180	5	effect	effect	NOUN
dpc-3558	180	6	of	of	ADP
dpc-3558	180	7	co	co	VERB
dpc-3558	180	8	-	-	ADJ
dpc-3558	180	9	harbouring	harbouring	ADJ
dpc-3558	180	10	mc1r	mc1r	NOUN
dpc-3558	180	11	alleles	allele	NOUN
dpc-3558	180	12	in	in	ADP
dpc-3558	180	13	genetically	genetically	ADV
dpc-3558	180	14	proven	prove	VERB
dpc-3558	180	15	xp	xp	NOUN
dpc-3558	180	16	cases	case	NOUN
dpc-3558	180	17	.	.	PUNCT
dpc-3558	181	1	a	a	DET
dpc-3558	181	2	previous	previous	ADJ
dpc-3558	181	3	study	study	NOUN
dpc-3558	181	4	of	of	ADP
dpc-3558	181	5	17	17	NUM
dpc-3558	181	6	nepalese	nepalese	ADJ
dpc-3558	181	7	xp	xp	NOUN
dpc-3558	181	8	patients	patient	NOUN
dpc-3558	181	9	suggested	suggest	VERB
dpc-3558	181	10	that	that	SCONJ
dpc-3558	181	11	the	the	DET
dpc-3558	181	12	p.r163q	p.r163q	NOUN
dpc-3558	181	13	mc1r	mc1r	NOUN
dpc-3558	181	14	variant	variant	NOUN
dpc-3558	181	15	in	in	ADP
dpc-3558	181	16	xpc	xpc	PROPN
dpc-3558	181	17	patients	patient	NOUN
dpc-3558	181	18	was	be	AUX
dpc-3558	181	19	associated	associate	VERB
dpc-3558	181	20	with	with	ADP
dpc-3558	181	21	younger	young	ADJ
dpc-3558	181	22	age	age	NOUN
dpc-3558	181	23	at	at	ADP
dpc-3558	181	24	first	first	ADJ
dpc-3558	181	25	carcinoma	carcinoma	NOUN
dpc-3558	181	26	and	and	CCONJ
dpc-3558	181	27	more	more	ADV
dpc-3558	181	28	numerous	numerous	ADJ
dpc-3558	181	29	cutaneous	cutaneous	ADJ
dpc-3558	181	30	carcinomas	carcinoma	NOUN
dpc-3558	181	31	,	,	PUNCT
dpc-3558	181	32	although	although	SCONJ
dpc-3558	181	33	this	this	DET
dpc-3558	181	34	latter	latter	ADJ
dpc-3558	181	35	difference	difference	NOUN
dpc-3558	181	36	was	be	AUX
dpc-3558	181	37	not	not	PART
dpc-3558	181	38	statistically	statistically	ADV
dpc-3558	181	39	significant	significant	ADJ
dpc-3558	181	40	[	[	X
dpc-3558	181	41	1	1	NUM
dpc-3558	181	42	]	]	PUNCT
dpc-3558	181	43	.	.	PUNCT
dpc-3558	182	1	additionally	additionally	ADV
dpc-3558	182	2	,	,	PUNCT
dpc-3558	182	3	it	it	PRON
dpc-3558	182	4	has	have	AUX
dpc-3558	182	5	been	be	AUX
dpc-3558	182	6	speculated	speculate	VERB
dpc-3558	182	7	that	that	SCONJ
dpc-3558	182	8	the	the	DET
dpc-3558	182	9	coexistence	coexistence	NOUN
dpc-3558	182	10	of	of	ADP
dpc-3558	182	11	xpc	xpc	PROPN
dpc-3558	182	12	mutation	mutation	NOUN
dpc-3558	182	13	with	with	ADP
dpc-3558	182	14	another	another	DET
dpc-3558	182	15	mc1r	mc1r	NOUN
dpc-3558	182	16	variant	variant	NOUN
dpc-3558	182	17	(	(	PUNCT
dpc-3558	182	18	p.v60l	p.v60l	PROPN
dpc-3558	182	19	)	)	PUNCT
dpc-3558	182	20	was	be	AUX
dpc-3558	182	21	associated	associate	VERB
dpc-3558	182	22	with	with	ADP
dpc-3558	182	23	multiple	multiple	ADJ
dpc-3558	182	24	primary	primary	ADJ
dpc-3558	182	25	melanoma	melanoma	NOUN
dpc-3558	182	26	phenotype	phenotype	NOUN
dpc-3558	182	27	in	in	ADP
dpc-3558	182	28	a	a	DET
dpc-3558	182	29	single	single	ADJ
dpc-3558	182	30	french	french	ADJ
dpc-3558	182	31	patient	patient	NOUN
dpc-3558	182	32	who	who	PRON
dpc-3558	182	33	had	have	VERB
dpc-3558	182	34	10	10	NUM
dpc-3558	182	35	melanomas	melanoma	NOUN
dpc-3558	182	36	and	and	CCONJ
dpc-3558	182	37	six	six	NUM
dpc-3558	182	38	bcc	bcc	NOUN
dpc-3558	182	39	before	before	ADP
dpc-3558	182	40	being	be	AUX
dpc-3558	182	41	diagnosed	diagnose	VERB
dpc-3558	182	42	with	with	ADP
dpc-3558	182	43	xp	xp	PROPN
dpc-3558	183	1	[	[	X
dpc-3558	183	2	12	12	NUM
dpc-3558	183	3	]	]	PUNCT
dpc-3558	183	4	.	.	PUNCT
dpc-3558	184	1	although	although	SCONJ
dpc-3558	184	2	the	the	DET
dpc-3558	184	3	putative	putative	ADJ
dpc-3558	184	4	modifier	modifier	NOUN
dpc-3558	184	5	effect	effect	NOUN
dpc-3558	184	6	on	on	ADP
dpc-3558	184	7	mc1r	mc1r	PROPN
dpc-3558	184	8	variant	variant	NOUN
dpc-3558	184	9	on	on	ADP
dpc-3558	184	10	the	the	DET
dpc-3558	184	11	phenotype	phenotype	NOUN
dpc-3558	184	12	of	of	ADP
dpc-3558	184	13	the	the	DET
dpc-3558	184	14	homozygous	homozygous	ADJ
dpc-3558	184	15	deleterious	deleterious	ADJ
dpc-3558	184	16	variant	variant	NOUN
dpc-3558	184	17	in	in	ADP
dpc-3558	184	18	the	the	DET
dpc-3558	184	19	xpc	xpc	PROPN
dpc-3558	184	20	gene	gene	NOUN
dpc-3558	184	21	is	be	AUX
dpc-3558	184	22	intriguing	intriguing	ADJ
dpc-3558	184	23	,	,	PUNCT
dpc-3558	184	24	it	it	PRON
dpc-3558	184	25	remains	remain	VERB
dpc-3558	184	26	currently	currently	ADV
dpc-3558	184	27	speculative	speculative	ADJ
dpc-3558	184	28	at	at	ADV
dpc-3558	184	29	best	well	ADV
dpc-3558	184	30	and	and	CCONJ
dpc-3558	184	31	awaits	await	VERB
dpc-3558	184	32	further	further	ADJ
dpc-3558	184	33	functional	functional	ADJ
dpc-3558	184	34	studies	study	NOUN
dpc-3558	184	35	and/	and/	ADJ
dpc-3558	184	36	or	or	CCONJ
dpc-3558	184	37	additional	additional	ADJ
dpc-3558	184	38	families	family	NOUN
dpc-3558	184	39	displaying	display	VERB
dpc-3558	184	40	similar	similar	ADJ
dpc-3558	184	41	effect	effect	NOUN
dpc-3558	184	42	.	.	PUNCT
dpc-3558	185	1	in	in	ADP
dpc-3558	185	2	conclusion	conclusion	NOUN
dpc-3558	185	3	,	,	PUNCT
dpc-3558	185	4	a	a	DET
dpc-3558	185	5	familial	familial	ADJ
dpc-3558	185	6	melanoma	melanoma	NOUN
dpc-3558	185	7	phenotype	phenotype	NOUN
dpc-3558	185	8	with	with	ADP
dpc-3558	185	9	a	a	DET
dpc-3558	185	10	presumed	presume	VERB
dpc-3558	185	11	autosomal	autosomal	ADJ
dpc-3558	185	12	recessive	recessive	ADJ
dpc-3558	185	13	inheritance	inheritance	NOUN
dpc-3558	185	14	pattern	pattern	NOUN
dpc-3558	185	15	was	be	AUX
dpc-3558	185	16	shown	show	VERB
dpc-3558	185	17	to	to	PART
dpc-3558	185	18	be	be	AUX
dpc-3558	185	19	atypical	atypical	ADJ
dpc-3558	185	20	in	in	ADP
dpc-3558	185	21	a	a	DET
dpc-3558	185	22	genetically	genetically	ADV
dpc-3558	185	23	proven	prove	VERB
dpc-3558	185	24	xp	xp	PROPN
dpc-3558	185	25	.	.	PUNCT
dpc-3558	186	1	the	the	DET
dpc-3558	186	2	role	role	NOUN
dpc-3558	186	3	,	,	PUNCT
dpc-3558	186	4	if	if	SCONJ
dpc-3558	186	5	any	any	PRON
dpc-3558	186	6	,	,	PUNCT
dpc-3558	186	7	of	of	ADP
dpc-3558	186	8	mc1r	mc1r	PROPN
dpc-3558	186	9	alleles	allele	NOUN
dpc-3558	186	10	in	in	ADP
dpc-3558	186	11	modifying	modify	VERB
dpc-3558	186	12	the	the	DET
dpc-3558	186	13	clinical	clinical	ADJ
dpc-3558	186	14	tumor	tumor	NOUN
dpc-3558	186	15	phenotype	phenotype	NOUN
dpc-3558	186	16	in	in	ADP
dpc-3558	186	17	xpc	xpc	PROPN
dpc-3558	186	18	mutation	mutation	NOUN
dpc-3558	186	19	carriers	carrier	NOUN
dpc-3558	186	20	is	be	AUX
dpc-3558	186	21	suggested	suggest	VERB
dpc-3558	186	22	.	.	PUNCT
dpc-3558	187	1	validation	validation	NOUN
dpc-3558	187	2	and	and	CCONJ
dpc-3558	187	3	extension	extension	NOUN
dpc-3558	187	4	of	of	ADP
dpc-3558	187	5	these	these	DET
dpc-3558	187	6	preliminary	preliminary	ADJ
dpc-3558	187	7	observations	observation	NOUN
dpc-3558	187	8	are	be	AUX
dpc-3558	187	9	needed	need	VERB
dpc-3558	187	10	.	.	PUNCT
dpc-3558	188	1	ethics	ethic	NOUN
dpc-3558	188	2	statement	statement	NOUN
dpc-3558	188	3	:	:	PUNCT
dpc-3558	188	4	this	this	DET
dpc-3558	188	5	study	study	NOUN
dpc-3558	188	6	was	be	AUX
dpc-3558	188	7	approved	approve	VERB
dpc-3558	188	8	by	by	ADP
dpc-3558	188	9	the	the	DET
dpc-3558	188	10	institutional	institutional	PROPN
dpc-3558	188	11	review	review	PROPN
dpc-3558	188	12	board	board	NOUN
dpc-3558	188	13	of	of	ADP
dpc-3558	188	14	universidade	universidade	PROPN
dpc-3558	188	15	federal	federal	PROPN
dpc-3558	188	16	de	de	PROPN
dpc-3558	188	17	minas	minas	PROPN
dpc-3558	188	18	gerais	gerais	PROPN
dpc-3558	188	19	(	(	PUNCT
dpc-3558	188	20	caae	caae	PROPN
dpc-3558	188	21	0472.0.203.240	0472.0.203.240	PROPN
dpc-3558	188	22	-	-	PUNCT
dpc-3558	188	23	11	11	NUM
dpc-3558	188	24	)	)	PUNCT
dpc-3558	188	25	.	.	PUNCT
dpc-3558	189	1	prior	prior	ADV
dpc-3558	189	2	to	to	ADP
dpc-3558	189	3	enrolment	enrolment	NOUN
dpc-3558	189	4	,	,	PUNCT
dpc-3558	189	5	written	write	VERB
dpc-3558	189	6	informed	informed	ADJ
dpc-3558	189	7	consent	consent	NOUN
dpc-3558	189	8	was	be	AUX
dpc-3558	189	9	obtained	obtain	VERB
dpc-3558	189	10	from	from	ADP
dpc-3558	189	11	all	all	DET
dpc-3558	189	12	patients	patient	NOUN
dpc-3558	189	13	.	.	PUNCT
dpc-3558	190	1	references	reference	NOUN
dpc-3558	190	2	1	1	NUM
dpc-3558	190	3	.	.	PUNCT
dpc-3558	191	1	espi	espi	PROPN
dpc-3558	191	2	p	p	PROPN
dpc-3558	191	3	,	,	PUNCT
dpc-3558	191	4	parajuli	parajuli	PROPN
dpc-3558	191	5	s	s	PROPN
dpc-3558	191	6	,	,	PUNCT
dpc-3558	191	7	benfodda	benfodda	PROPN
dpc-3558	191	8	m	m	PROPN
dpc-3558	191	9	,	,	PUNCT
dpc-3558	191	10	et	et	PROPN
dpc-3558	191	11	al	al	PROPN
dpc-3558	191	12	.	.	PROPN
dpc-3558	192	1	clinical	clinical	ADJ
dpc-3558	192	2	and	and	CCONJ
dpc-3558	192	3	genetic	genetic	ADJ
dpc-3558	192	4	characteristics	characteristic	NOUN
dpc-3558	192	5	of	of	ADP
dpc-3558	192	6	xeroderma	xeroderma	PROPN
dpc-3558	192	7	pigmentosum	pigmentosum	PROPN
dpc-3558	192	8	in	in	ADP
dpc-3558	192	9	nepal	nepal	PROPN
dpc-3558	192	10	.	.	PUNCT
dpc-3558	193	1	j	j	PROPN
dpc-3558	193	2	eur	eur	PROPN
dpc-3558	193	3	acad	acad	PROPN
dpc-3558	193	4	dermatol	dermatol	NOUN
dpc-3558	193	5	venereol	venereol	NOUN
dpc-3558	193	6	.	.	PUNCT
dpc-3558	194	1	2018;32(5):832	2018;32(5):832	NUM
dpc-3558	194	2	-	-	PUNCT
dpc-3558	194	3	839	839	NUM
dpc-3558	194	4	.	.	PUNCT
dpc-3558	195	1	doi	doi	NOUN
dpc-3558	195	2	:	:	PUNCT
dpc-3558	195	3	10.1111	10.1111	NUM
dpc-3558	195	4	/	/	SYM
dpc-3558	195	5	jdv.14717	jdv.14717	PROPN
dpc-3558	195	6	.	.	PUNCT
dpc-3558	196	1	pmid	pmid	NOUN
dpc-3558	196	2	:	:	PUNCT
dpc-3558	196	3	29178624	29178624	NUM
dpc-3558	196	4	.	.	PUNCT
dpc-3558	197	1	2	2	X
dpc-3558	197	2	.	.	X
dpc-3558	197	3	ijaz	ijaz	PROPN
dpc-3558	197	4	a	a	PROPN
dpc-3558	197	5	,	,	PUNCT
dpc-3558	197	6	basit	basit	PROPN
dpc-3558	197	7	s	s	PROPN
dpc-3558	197	8	,	,	PUNCT
dpc-3558	197	9	gul	gul	PROPN
dpc-3558	197	10	a	a	X
dpc-3558	197	11	,	,	PUNCT
dpc-3558	197	12	et	et	PROPN
dpc-3558	197	13	al	al	PROPN
dpc-3558	197	14	.	.	PUNCT
dpc-3558	197	15	xpc	xpc	PROPN
dpc-3558	197	16	gene	gene	NOUN
dpc-3558	197	17	mutations	mutation	NOUN
dpc-3558	197	18	in	in	ADP
dpc-3558	197	19	families	family	NOUN
dpc-3558	197	20	with	with	ADP
dpc-3558	197	21	xeroderma	xeroderma	PROPN
dpc-3558	197	22	pigmentosum	pigmentosum	PROPN
dpc-3558	197	23	from	from	ADP
dpc-3558	197	24	pakistan	pakistan	PROPN
dpc-3558	197	25	;	;	PUNCT
dpc-3558	197	26	prevalent	prevalent	ADJ
dpc-3558	197	27	founder	founder	NOUN
dpc-3558	197	28	effect	effect	NOUN
dpc-3558	197	29	.	.	PUNCT
dpc-3558	198	1	congenit	congenit	VERB
dpc-3558	198	2	anom	anom	PROPN
dpc-3558	198	3	(	(	PUNCT
dpc-3558	198	4	kyoto	kyoto	PROPN
dpc-3558	198	5	)	)	PUNCT
dpc-3558	198	6	.	.	PUNCT
dpc-3558	199	1	2019;59(1):18	2019;59(1):18	NUM
dpc-3558	199	2	-	-	SYM
dpc-3558	199	3	21	21	NUM
dpc-3558	199	4	.	.	PUNCT
dpc-3558	200	1	doi	doi	NOUN
dpc-3558	200	2	:	:	PUNCT
dpc-3558	200	3	10.1111	10.1111	NUM
dpc-3558	200	4	/	/	SYM
dpc-3558	200	5	cga	cga	PROPN
dpc-3558	200	6	.12281	.12281	PROPN
dpc-3558	200	7	.	.	PUNCT
dpc-3558	201	1	pmid	pmid	PROPN
dpc-3558	201	2	:	:	PUNCT
dpc-3558	201	3	29569758	29569758	NUM
dpc-3558	201	4	.	.	PUNCT