id	sid	tid	token	lemma	pos
dpc-3935	1	1	dermatology	dermatology	NOUN
dpc-3935	1	2	:	:	PUNCT
dpc-3935	1	3	practical	practical	ADJ
dpc-3935	1	4	and	and	CCONJ
dpc-3935	1	5	conceptual	conceptual	ADJ
dpc-3935	1	6	original	original	ADJ
dpc-3935	1	7	article	article	NOUN
dpc-3935	1	8	|	|	ADV
dpc-3935	1	9	dermatol	dermatol	ADJ
dpc-3935	1	10	pract	pract	NOUN
dpc-3935	1	11	concept	concept	NOUN
dpc-3935	1	12	.	.	PUNCT
dpc-3935	2	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	2	2	1	1	NUM
dpc-3935	2	3	prevalence	prevalence	NOUN
dpc-3935	2	4	of	of	ADP
dpc-3935	2	5	cdkn2a	cdkn2a	PROPN
dpc-3935	2	6	,	,	PUNCT
dpc-3935	2	7	cdk4	cdk4	NOUN
dpc-3935	2	8	,	,	PUNCT
dpc-3935	2	9	pot1	pot1	PROPN
dpc-3935	2	10	,	,	PUNCT
dpc-3935	2	11	bap1	bap1	PROPN
dpc-3935	2	12	,	,	PUNCT
dpc-3935	2	13	mitf	mitf	NOUN
dpc-3935	2	14	,	,	PUNCT
dpc-3935	2	15	atm	atm	ADJ
dpc-3935	2	16	,	,	PUNCT
dpc-3935	2	17	and	and	CCONJ
dpc-3935	2	18	tert	tert	NOUN
dpc-3935	2	19	pathogenic	pathogenic	ADJ
dpc-3935	2	20	variants	variant	NOUN
dpc-3935	2	21	in	in	ADP
dpc-3935	2	22	a	a	DET
dpc-3935	2	23	single	single	ADJ
dpc-3935	2	24	-	-	PUNCT
dpc-3935	2	25	center	center	NOUN
dpc-3935	2	26	retrospective	retrospective	ADJ
dpc-3935	2	27	series	series	NOUN
dpc-3935	2	28	of	of	ADP
dpc-3935	2	29	patients	patient	NOUN
dpc-3935	2	30	with	with	ADP
dpc-3935	2	31	melanoma	melanoma	NOUN
dpc-3935	2	32	and	and	CCONJ
dpc-3935	2	33	personal	personal	ADJ
dpc-3935	2	34	or	or	CCONJ
dpc-3935	2	35	family	family	NOUN
dpc-3935	2	36	history	history	NOUN
dpc-3935	2	37	suggestive	suggestive	ADJ
dpc-3935	2	38	of	of	ADP
dpc-3935	2	39	genetic	genetic	ADJ
dpc-3935	2	40	predisposition	predisposition	NOUN
dpc-3935	2	41	giada	giada	PROPN
dpc-3935	2	42	ferrara1	ferrara1	PROPN
dpc-3935	2	43	,	,	PUNCT
dpc-3935	2	44	salvatore	salvatore	PROPN
dpc-3935	2	45	paiella2	paiella2	PROPN
dpc-3935	2	46	,	,	PUNCT
dpc-3935	2	47	giulio	giulio	PROPN
dpc-3935	2	48	settanni3	settanni3	PROPN
dpc-3935	2	49	,	,	PUNCT
dpc-3935	2	50	melissa	melissa	PROPN
dpc-3935	2	51	frizziero4	frizziero4	PROPN
dpc-3935	2	52	,	,	PUNCT
dpc-3935	2	53	paolo	paolo	PROPN
dpc-3935	2	54	rosina1	rosina1	PROPN
dpc-3935	2	55	,	,	PUNCT
dpc-3935	2	56	valeria	valeria	PROPN
dpc-3935	2	57	 	 	SPACE
dpc-3935	2	58	viassolo5	viassolo5	NOUN
dpc-3935	2	59	1	1	NUM
dpc-3935	2	60	section	section	NOUN
dpc-3935	2	61	of	of	ADP
dpc-3935	2	62	dermatology	dermatology	NOUN
dpc-3935	2	63	and	and	CCONJ
dpc-3935	2	64	venereology	venereology	NOUN
dpc-3935	2	65	,	,	PUNCT
dpc-3935	2	66	department	department	NOUN
dpc-3935	2	67	of	of	ADP
dpc-3935	2	68	medicine	medicine	NOUN
dpc-3935	2	69	,	,	PUNCT
dpc-3935	2	70	university	university	NOUN
dpc-3935	2	71	of	of	ADP
dpc-3935	2	72	verona	verona	PROPN
dpc-3935	2	73	,	,	PUNCT
dpc-3935	2	74	verona	verona	PROPN
dpc-3935	2	75	,	,	PUNCT
dpc-3935	2	76	italy	italy	PROPN
dpc-3935	2	77	2	2	NUM
dpc-3935	2	78	pancreatic	pancreatic	ADJ
dpc-3935	2	79	surgery	surgery	NOUN
dpc-3935	2	80	unit	unit	NOUN
dpc-3935	2	81	,	,	PUNCT
dpc-3935	2	82	pancreas	pancreas	PROPN
dpc-3935	2	83	institute	institute	PROPN
dpc-3935	2	84	,	,	PUNCT
dpc-3935	2	85	university	university	PROPN
dpc-3935	2	86	of	of	ADP
dpc-3935	2	87	verona	verona	PROPN
dpc-3935	2	88	,	,	PUNCT
dpc-3935	2	89	verona	verona	PROPN
dpc-3935	2	90	,	,	PUNCT
dpc-3935	2	91	italy	italy	PROPN
dpc-3935	2	92	3	3	NUM
dpc-3935	2	93	pathology	pathology	NOUN
dpc-3935	2	94	unit	unit	NOUN
dpc-3935	2	95	,	,	PUNCT
dpc-3935	2	96	irccs	irccs	PROPN
dpc-3935	2	97	sacro	sacro	PROPN
dpc-3935	2	98	cuore	cuore	PROPN
dpc-3935	2	99	don	don	PROPN
dpc-3935	2	100	calabria	calabria	PROPN
dpc-3935	2	101	hospital	hospital	PROPN
dpc-3935	2	102	,	,	PUNCT
dpc-3935	2	103	negrar	negrar	PROPN
dpc-3935	2	104	di	di	PROPN
dpc-3935	2	105	valpolicella	valpolicella	PROPN
dpc-3935	2	106	,	,	PUNCT
dpc-3935	2	107	verona	verona	PROPN
dpc-3935	2	108	,	,	PUNCT
dpc-3935	2	109	italy	italy	PROPN
dpc-3935	2	110	4	4	NUM
dpc-3935	2	111	cancer	cancer	NOUN
dpc-3935	2	112	research	research	PROPN
dpc-3935	2	113	uk	uk	PROPN
dpc-3935	2	114	manchester	manchester	PROPN
dpc-3935	2	115	institute	institute	PROPN
dpc-3935	2	116	cancer	cancer	PROPN
dpc-3935	2	117	biomarker	biomarker	PROPN
dpc-3935	2	118	centre	centre	PROPN
dpc-3935	2	119	,	,	PUNCT
dpc-3935	2	120	manchester	manchester	PROPN
dpc-3935	2	121	,	,	PUNCT
dpc-3935	2	122	uk	uk	PROPN
dpc-3935	2	123	5	5	NUM
dpc-3935	2	124	medical	medical	ADJ
dpc-3935	2	125	genetics	genetic	NOUN
dpc-3935	2	126	,	,	PUNCT
dpc-3935	2	127	irccs	irccs	PROPN
dpc-3935	2	128	sacro	sacro	PROPN
dpc-3935	2	129	cuore	cuore	PROPN
dpc-3935	2	130	don	don	PROPN
dpc-3935	2	131	calabria	calabria	PROPN
dpc-3935	2	132	hospital	hospital	PROPN
dpc-3935	2	133	,	,	PUNCT
dpc-3935	2	134	negrar	negrar	PROPN
dpc-3935	2	135	di	di	PROPN
dpc-3935	2	136	valpolicella	valpolicella	PROPN
dpc-3935	2	137	,	,	PUNCT
dpc-3935	2	138	verona	verona	PROPN
dpc-3935	2	139	,	,	PUNCT
dpc-3935	2	140	italy	italy	PROPN
dpc-3935	2	141	key	key	ADJ
dpc-3935	2	142	words	word	NOUN
dpc-3935	2	143	:	:	PUNCT
dpc-3935	2	144	melanoma	melanoma	NOUN
dpc-3935	2	145	,	,	PUNCT
dpc-3935	2	146	cdkn2a	cdkn2a	PROPN
dpc-3935	2	147	,	,	PUNCT
dpc-3935	2	148	mitf	mitf	NOUN
dpc-3935	2	149	,	,	PUNCT
dpc-3935	2	150	genetic	genetic	ADJ
dpc-3935	2	151	predisposition	predisposition	NOUN
dpc-3935	2	152	,	,	PUNCT
dpc-3935	2	153	pancreatic	pancreatic	ADJ
dpc-3935	2	154	cancer	cancer	NOUN
dpc-3935	2	155	citation	citation	NOUN
dpc-3935	2	156	:	:	PUNCT
dpc-3935	2	157	ferrara	ferrara	NOUN
dpc-3935	2	158	g	g	PROPN
dpc-3935	2	159	,	,	PUNCT
dpc-3935	2	160	paiella	paiella	PROPN
dpc-3935	2	161	s	s	PROPN
dpc-3935	2	162	,	,	PUNCT
dpc-3935	2	163	settanni	settanni	PROPN
dpc-3935	2	164	g	g	PROPN
dpc-3935	2	165	,	,	PUNCT
dpc-3935	2	166	frizziero	frizziero	PROPN
dpc-3935	2	167	m	m	PROPN
dpc-3935	2	168	,	,	PUNCT
dpc-3935	2	169	rosina	rosina	PROPN
dpc-3935	2	170	p	p	PROPN
dpc-3935	2	171	,	,	PUNCT
dpc-3935	2	172	viassolo	viassolo	PROPN
dpc-3935	2	173	v.	v.	PRON
dpc-3935	2	174	prevalence	prevalence	NOUN
dpc-3935	2	175	of	of	ADP
dpc-3935	2	176	cdkn2a	cdkn2a	PROPN
dpc-3935	2	177	,	,	PUNCT
dpc-3935	2	178	cdk4	cdk4	NOUN
dpc-3935	2	179	,	,	PUNCT
dpc-3935	2	180	pot1	pot1	PROPN
dpc-3935	2	181	,	,	PUNCT
dpc-3935	2	182	bap1	bap1	PROPN
dpc-3935	2	183	,	,	PUNCT
dpc-3935	2	184	mitf	mitf	NOUN
dpc-3935	2	185	,	,	PUNCT
dpc-3935	2	186	atm	atm	ADJ
dpc-3935	2	187	,	,	PUNCT
dpc-3935	2	188	and	and	CCONJ
dpc-3935	2	189	tert	tert	NOUN
dpc-3935	2	190	pathogenic	pathogenic	ADJ
dpc-3935	2	191	variants	variant	NOUN
dpc-3935	2	192	in	in	ADP
dpc-3935	2	193	a	a	DET
dpc-3935	2	194	single	single	ADJ
dpc-3935	2	195	-	-	PUNCT
dpc-3935	2	196	center	center	NOUN
dpc-3935	2	197	retrospective	retrospective	ADJ
dpc-3935	2	198	series	series	NOUN
dpc-3935	2	199	of	of	ADP
dpc-3935	2	200	patients	patient	NOUN
dpc-3935	2	201	with	with	ADP
dpc-3935	2	202	melanoma	melanoma	NOUN
dpc-3935	2	203	and	and	CCONJ
dpc-3935	2	204	personal	personal	ADJ
dpc-3935	2	205	or	or	CCONJ
dpc-3935	2	206	family	family	NOUN
dpc-3935	2	207	history	history	NOUN
dpc-3935	2	208	suggestive	suggestive	ADJ
dpc-3935	2	209	of	of	ADP
dpc-3935	2	210	genetic	genetic	ADJ
dpc-3935	2	211	predisposition	predisposition	NOUN
dpc-3935	2	212	.	.	PUNCT
dpc-3935	3	1	dermatol	dermatol	NOUN
dpc-3935	3	2	pract	pract	PROPN
dpc-3935	3	3	concept	concept	NOUN
dpc-3935	3	4	.	.	PUNCT
dpc-3935	4	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	4	2	.	.	X
dpc-3935	4	3	doi	doi	PROPN
dpc-3935	4	4	:	:	PUNCT
dpc-3935	4	5	https://doi.org/10.5826/dpc.1403a120	https://doi.org/10.5826/dpc.1403a120	PROPN
dpc-3935	4	6	accepted	accept	VERB
dpc-3935	4	7	:	:	PUNCT
dpc-3935	4	8	february	february	PROPN
dpc-3935	4	9	1	1	NUM
dpc-3935	4	10	,	,	PUNCT
dpc-3935	4	11	2024	2024	NUM
dpc-3935	4	12	;	;	PUNCT
dpc-3935	4	13	published	publish	VERB
dpc-3935	4	14	:	:	PUNCT
dpc-3935	5	1	july	july	PROPN
dpc-3935	5	2	2024	2024	NUM
dpc-3935	5	3	copyright	copyright	NOUN
dpc-3935	5	4	:	:	PUNCT
dpc-3935	5	5	©	©	PROPN
dpc-3935	5	6	2024	2024	NUM
dpc-3935	5	7	ferrara	ferrara	NOUN
dpc-3935	5	8	et	et	PROPN
dpc-3935	5	9	al	al	PROPN
dpc-3935	5	10	.	.	PUNCT
dpc-3935	6	1	this	this	PRON
dpc-3935	6	2	is	be	AUX
dpc-3935	6	3	an	an	DET
dpc-3935	6	4	open	open	ADJ
dpc-3935	6	5	-	-	PUNCT
dpc-3935	6	6	access	access	NOUN
dpc-3935	6	7	article	article	NOUN
dpc-3935	6	8	distributed	distribute	VERB
dpc-3935	6	9	under	under	ADP
dpc-3935	6	10	the	the	DET
dpc-3935	6	11	terms	term	NOUN
dpc-3935	6	12	of	of	ADP
dpc-3935	6	13	the	the	DET
dpc-3935	6	14	creative	creative	ADJ
dpc-3935	6	15	commons	common	NOUN
dpc-3935	6	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-3935	6	17	license	license	NOUN
dpc-3935	6	18	(	(	PUNCT
dpc-3935	6	19	by	by	ADP
dpc-3935	6	20	-	-	PUNCT
dpc-3935	6	21	nc-4.0	nc-4.0	NOUN
dpc-3935	6	22	)	)	PUNCT
dpc-3935	6	23	,	,	PUNCT
dpc-3935	6	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-3935	6	25	,	,	PUNCT
dpc-3935	6	26	which	which	PRON
dpc-3935	6	27	permits	permit	VERB
dpc-3935	6	28	unrestricted	unrestricted	ADJ
dpc-3935	6	29	noncommercial	noncommercial	ADJ
dpc-3935	6	30	use	use	NOUN
dpc-3935	6	31	,	,	PUNCT
dpc-3935	6	32	distribution	distribution	NOUN
dpc-3935	6	33	,	,	PUNCT
dpc-3935	6	34	and	and	CCONJ
dpc-3935	6	35	reproduction	reproduction	NOUN
dpc-3935	6	36	in	in	ADP
dpc-3935	6	37	any	any	DET
dpc-3935	6	38	medium	medium	NOUN
dpc-3935	6	39	,	,	PUNCT
dpc-3935	6	40	provided	provide	VERB
dpc-3935	6	41	the	the	DET
dpc-3935	6	42	original	original	ADJ
dpc-3935	6	43	authors	author	NOUN
dpc-3935	6	44	and	and	CCONJ
dpc-3935	6	45	source	source	NOUN
dpc-3935	6	46	are	be	AUX
dpc-3935	6	47	credited	credit	VERB
dpc-3935	6	48	.	.	PUNCT
dpc-3935	7	1	funding	funding	NOUN
dpc-3935	7	2	:	:	PUNCT
dpc-3935	7	3	none	none	NOUN
dpc-3935	7	4	.	.	PUNCT
dpc-3935	8	1	competing	compete	VERB
dpc-3935	8	2	interests	interest	NOUN
dpc-3935	8	3	:	:	PUNCT
dpc-3935	8	4	sp	sp	NOUN
dpc-3935	8	5	receives	receive	VERB
dpc-3935	8	6	consultancy	consultancy	NOUN
dpc-3935	8	7	honoraria	honorarium	NOUN
dpc-3935	8	8	from	from	ADP
dpc-3935	8	9	alphatau	alphatau	PROPN
dpc-3935	8	10	.	.	PUNCT
dpc-3935	9	1	authorship	authorship	NOUN
dpc-3935	9	2	:	:	PUNCT
dpc-3935	9	3	all	all	DET
dpc-3935	9	4	authors	author	NOUN
dpc-3935	9	5	have	have	AUX
dpc-3935	9	6	contributed	contribute	VERB
dpc-3935	9	7	significantly	significantly	ADV
dpc-3935	9	8	to	to	ADP
dpc-3935	9	9	this	this	DET
dpc-3935	9	10	publication	publication	NOUN
dpc-3935	9	11	.	.	PUNCT
dpc-3935	10	1	corresponding	correspond	VERB
dpc-3935	10	2	author	author	NOUN
dpc-3935	10	3	:	:	PUNCT
dpc-3935	10	4	valeria	valeria	PROPN
dpc-3935	10	5	viassolo	viassolo	PROPN
dpc-3935	10	6	,	,	PUNCT
dpc-3935	10	7	medical	medical	ADJ
dpc-3935	10	8	genetics	genetic	NOUN
dpc-3935	10	9	,	,	PUNCT
dpc-3935	10	10	irccs	irccs	PROPN
dpc-3935	10	11	sacro	sacro	PROPN
dpc-3935	10	12	cuore	cuore	PROPN
dpc-3935	10	13	don	don	PROPN
dpc-3935	10	14	calabria	calabria	PROPN
dpc-3935	10	15	hospital	hospital	PROPN
dpc-3935	10	16	,	,	PUNCT
dpc-3935	10	17	via	via	ADP
dpc-3935	10	18	don	don	PROPN
dpc-3935	10	19	a.	a.	NOUN
dpc-3935	10	20	sempreboni	sempreboni	PROPN
dpc-3935	10	21	5	5	NUM
dpc-3935	10	22	,	,	PUNCT
dpc-3935	10	23	37024	37024	NUM
dpc-3935	10	24	,	,	PUNCT
dpc-3935	10	25	negrar	negrar	PROPN
dpc-3935	10	26	di	di	X
dpc-3935	10	27	valpolicella	valpolicella	PROPN
dpc-3935	10	28	(	(	PUNCT
dpc-3935	10	29	vr	vr	PROPN
dpc-3935	10	30	)	)	PUNCT
dpc-3935	10	31	,	,	PUNCT
dpc-3935	10	32	italy	italy	PROPN
dpc-3935	10	33	.	.	PUNCT
dpc-3935	11	1	email	email	NOUN
dpc-3935	11	2	:	:	PUNCT
dpc-3935	11	3	valeria.viassolo@sacrocuore.it	valeria.viassolo@sacrocuore.it	NOUN
dpc-3935	11	4	introduction	introduction	NOUN
dpc-3935	11	5	:	:	PUNCT
dpc-3935	11	6	approximately	approximately	ADV
dpc-3935	11	7	20%-45	20%-45	NUM
dpc-3935	11	8	%	%	NOUN
dpc-3935	11	9	of	of	ADP
dpc-3935	11	10	familial	familial	ADJ
dpc-3935	11	11	melanoma	melanoma	NOUN
dpc-3935	11	12	(	(	PUNCT
dpc-3935	11	13	fm	fm	NOUN
dpc-3935	11	14	)	)	PUNCT
dpc-3935	11	15	cases	case	NOUN
dpc-3935	11	16	are	be	AUX
dpc-3935	11	17	associated	associate	VERB
dpc-3935	11	18	with	with	ADP
dpc-3935	11	19	genetic	genetic	ADJ
dpc-3935	11	20	predisposition	predisposition	NOUN
dpc-3935	11	21	.	.	PUNCT
dpc-3935	12	1	objectives	objective	NOUN
dpc-3935	12	2	:	:	PUNCT
dpc-3935	12	3	this	this	DET
dpc-3935	12	4	single	single	ADJ
dpc-3935	12	5	-	-	PUNCT
dpc-3935	12	6	center	center	NOUN
dpc-3935	12	7	retrospective	retrospective	ADJ
dpc-3935	12	8	study	study	NOUN
dpc-3935	12	9	aimed	aim	VERB
dpc-3935	12	10	to	to	PART
dpc-3935	12	11	assess	assess	VERB
dpc-3935	12	12	the	the	DET
dpc-3935	12	13	frequency	frequency	NOUN
dpc-3935	12	14	of	of	ADP
dpc-3935	12	15	pathogenic	pathogenic	ADJ
dpc-3935	12	16	variants	variant	NOUN
dpc-3935	12	17	(	(	PUNCT
dpc-3935	12	18	pv	pv	NOUN
dpc-3935	12	19	)	)	PUNCT
dpc-3935	12	20	in	in	ADP
dpc-3935	12	21	the	the	DET
dpc-3935	12	22	main	main	ADJ
dpc-3935	12	23	melanoma	melanoma	NOUN
dpc-3935	12	24	-	-	PUNCT
dpc-3935	12	25	predisposing	predispose	VERB
dpc-3935	12	26	genes	gene	NOUN
dpc-3935	12	27	in	in	ADP
dpc-3935	12	28	patients	patient	NOUN
dpc-3935	12	29	with	with	ADP
dpc-3935	12	30	cutaneous	cutaneous	ADJ
dpc-3935	12	31	melanoma	melanoma	NOUN
dpc-3935	12	32	and	and	CCONJ
dpc-3935	12	33	investigate	investigate	VERB
dpc-3935	12	34	the	the	DET
dpc-3935	12	35	clinical	clinical	ADJ
dpc-3935	12	36	predictors	predictor	NOUN
dpc-3935	12	37	of	of	ADP
dpc-3935	12	38	genetic	genetic	ADJ
dpc-3935	12	39	predisposition	predisposition	NOUN
dpc-3935	12	40	.	.	PUNCT
dpc-3935	13	1	methods	method	NOUN
dpc-3935	13	2	:	:	PUNCT
dpc-3935	13	3	patients	patient	NOUN
dpc-3935	13	4	included	include	VERB
dpc-3935	13	5	were	be	AUX
dpc-3935	13	6	those	those	PRON
dpc-3935	13	7	diagnosed	diagnose	VERB
dpc-3935	13	8	with	with	ADP
dpc-3935	13	9	cutaneous	cutaneous	ADJ
dpc-3935	13	10	melanoma	melanoma	NOUN
dpc-3935	13	11	at	at	ADP
dpc-3935	13	12	the	the	DET
dpc-3935	13	13	dermatology	dermatology	NOUN
dpc-3935	13	14	unit	unit	NOUN
dpc-3935	13	15	of	of	ADP
dpc-3935	13	16	the	the	DET
dpc-3935	13	17	university	university	NOUN
dpc-3935	13	18	hospital	hospital	NOUN
dpc-3935	13	19	of	of	ADP
dpc-3935	13	20	verona	verona	PROPN
dpc-3935	13	21	,	,	PUNCT
dpc-3935	13	22	italy	italy	PROPN
dpc-3935	13	23	,	,	PUNCT
dpc-3935	13	24	from	from	ADP
dpc-3935	13	25	2000	2000	NUM
dpc-3935	13	26	to	to	ADP
dpc-3935	13	27	2022	2022	NUM
dpc-3935	13	28	,	,	PUNCT
dpc-3935	13	29	presenting	present	VERB
dpc-3935	13	30	at	at	ADP
dpc-3935	13	31	least	least	ADJ
dpc-3935	13	32	one	one	NUM
dpc-3935	13	33	of	of	ADP
dpc-3935	13	34	the	the	DET
dpc-3935	13	35	followings	following	NOUN
dpc-3935	13	36	:	:	PUNCT
dpc-3935	13	37	multiple	multiple	ADJ
dpc-3935	13	38	melanomas	melanomas	NOUN
dpc-3935	13	39	(	(	PUNCT
dpc-3935	13	40	≥	≥	NOUN
dpc-3935	13	41	3	3	NUM
dpc-3935	13	42	)	)	PUNCT
dpc-3935	13	43	;	;	PUNCT
dpc-3935	13	44	personal	personal	ADJ
dpc-3935	13	45	/	/	SYM
dpc-3935	13	46	family	family	NOUN
dpc-3935	13	47	history	history	NOUN
dpc-3935	13	48	of	of	ADP
dpc-3935	13	49	pancreatic	pancreatic	ADJ
dpc-3935	13	50	cancer	cancer	NOUN
dpc-3935	13	51	(	(	PUNCT
dpc-3935	13	52	pc	pc	NOUN
dpc-3935	13	53	)	)	PUNCT
dpc-3935	13	54	(	(	PUNCT
dpc-3935	13	55	up	up	ADP
dpc-3935	13	56	to	to	ADP
dpc-3935	13	57	2nd	2nd	ADJ
dpc-3935	13	58	-	-	PUNCT
dpc-3935	13	59	degree	degree	NOUN
dpc-3935	13	60	relatives	relative	NOUN
dpc-3935	13	61	)	)	PUNCT
dpc-3935	13	62	;	;	PUNCT
dpc-3935	13	63	≥	≥	NUM
dpc-3935	13	64	2	2	NUM
dpc-3935	13	65	1st	1st	ADJ
dpc-3935	13	66	-	-	PUNCT
dpc-3935	13	67	degree	degree	NOUN
dpc-3935	13	68	relatives	relative	NOUN
dpc-3935	13	69	with	with	ADP
dpc-3935	13	70	melanoma	melanoma	NOUN
dpc-3935	13	71	;	;	PUNCT
dpc-3935	13	72	≥	≥	NUM
dpc-3935	13	73	1	1	NUM
dpc-3935	13	74	1st	1st	ADJ
dpc-3935	13	75	-	-	PUNCT
dpc-3935	13	76	degree	degree	NOUN
dpc-3935	13	77	relatives	relative	NOUN
dpc-3935	13	78	with	with	ADP
dpc-3935	13	79	early	early	ADJ
dpc-3935	13	80	-	-	PUNCT
dpc-3935	13	81	onset	onset	NOUN
dpc-3935	13	82	(	(	PUNCT
dpc-3935	13	83	<	<	X
dpc-3935	13	84	45	45	NUM
dpc-3935	13	85	years	year	NOUN
dpc-3935	13	86	)	)	PUNCT
dpc-3935	13	87	melanoma	melanoma	NOUN
dpc-3935	13	88	and	and	CCONJ
dpc-3935	13	89	tested	test	VERB
dpc-3935	13	90	for	for	ADP
dpc-3935	13	91	cdkn2a	cdkn2a	PROPN
dpc-3935	13	92	,	,	PUNCT
dpc-3935	13	93	cdk4	cdk4	NOUN
dpc-3935	13	94	,	,	PUNCT
dpc-3935	13	95	pot1	pot1	PROPN
dpc-3935	13	96	,	,	PUNCT
dpc-3935	13	97	bap1	bap1	PROPN
dpc-3935	13	98	,	,	PUNCT
dpc-3935	13	99	mitf	mitf	NOUN
dpc-3935	13	100	,	,	PUNCT
dpc-3935	13	101	atm	atm	ADJ
dpc-3935	13	102	,	,	PUNCT
dpc-3935	13	103	and	and	CCONJ
dpc-3935	13	104	tert	tert	NOUN
dpc-3935	13	105	.	.	PUNCT
dpc-3935	14	1	abstract	abstract	ADJ
dpc-3935	14	2	2	2	NUM
dpc-3935	14	3	original	original	ADJ
dpc-3935	14	4	article	article	NOUN
dpc-3935	14	5	|	|	ADV
dpc-3935	14	6	dermatol	dermatol	ADJ
dpc-3935	14	7	pract	pract	NOUN
dpc-3935	14	8	concept	concept	NOUN
dpc-3935	14	9	.	.	PUNCT
dpc-3935	15	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	15	2	introduction	introduction	NOUN
dpc-3935	15	3	melanoma	melanoma	NOUN
dpc-3935	15	4	is	be	AUX
dpc-3935	15	5	a	a	DET
dpc-3935	15	6	skin	skin	NOUN
dpc-3935	15	7	cancer	cancer	NOUN
dpc-3935	15	8	that	that	PRON
dpc-3935	15	9	originates	originate	VERB
dpc-3935	15	10	from	from	ADP
dpc-3935	15	11	the	the	DET
dpc-3935	15	12	neoplastic	neoplastic	ADJ
dpc-3935	15	13	transformation	transformation	NOUN
dpc-3935	15	14	of	of	ADP
dpc-3935	15	15	melanocytes	melanocyte	NOUN
dpc-3935	15	16	.	.	PUNCT
dpc-3935	16	1	previously	previously	ADV
dpc-3935	16	2	considered	consider	VERB
dpc-3935	16	3	a	a	DET
dpc-3935	16	4	rare	rare	ADJ
dpc-3935	16	5	diagnosis	diagnosis	NOUN
dpc-3935	16	6	,	,	PUNCT
dpc-3935	16	7	its	its	PRON
dpc-3935	16	8	incidence	incidence	NOUN
dpc-3935	16	9	has	have	AUX
dpc-3935	16	10	grown	grow	VERB
dpc-3935	16	11	worldwide	worldwide	ADV
dpc-3935	16	12	in	in	ADP
dpc-3935	16	13	recent	recent	ADJ
dpc-3935	16	14	decades	decade	NOUN
dpc-3935	17	1	[	[	X
dpc-3935	17	2	1,2	1,2	NUM
dpc-3935	17	3	]	]	PUNCT
dpc-3935	17	4	.	.	PUNCT
dpc-3935	18	1	according	accord	VERB
dpc-3935	18	2	to	to	ADP
dpc-3935	18	3	the	the	DET
dpc-3935	18	4	patient	patient	ADJ
dpc-3935	18	5	family	family	NOUN
dpc-3935	18	6	history	history	NOUN
dpc-3935	18	7	,	,	PUNCT
dpc-3935	18	8	melanoma	melanoma	PROPN
dpc-3935	18	9	can	can	AUX
dpc-3935	18	10	be	be	AUX
dpc-3935	18	11	classified	classify	VERB
dpc-3935	18	12	as	as	ADP
dpc-3935	18	13	sporadic	sporadic	ADJ
dpc-3935	18	14	or	or	CCONJ
dpc-3935	18	15	familial	familial	ADJ
dpc-3935	18	16	(	(	PUNCT
dpc-3935	18	17	fm	fm	NOUN
dpc-3935	18	18	)	)	PUNCT
dpc-3935	18	19	.	.	PUNCT
dpc-3935	19	1	randomly	randomly	ADV
dpc-3935	19	2	acquired	acquire	VERB
dpc-3935	19	3	genomic	genomic	ADJ
dpc-3935	19	4	changes	change	NOUN
dpc-3935	19	5	in	in	ADP
dpc-3935	19	6	melanocytes	melanocyte	NOUN
dpc-3935	19	7	resulting	result	VERB
dpc-3935	19	8	from	from	ADP
dpc-3935	19	9	environmental	environmental	ADJ
dpc-3935	19	10	factors	factor	NOUN
dpc-3935	19	11	or	or	CCONJ
dpc-3935	19	12	aging	aging	NOUN
dpc-3935	19	13	and	and	CCONJ
dpc-3935	19	14	favored	favor	VERB
dpc-3935	19	15	by	by	ADP
dpc-3935	19	16	certain	certain	ADJ
dpc-3935	19	17	phenotypic	phenotypic	ADJ
dpc-3935	19	18	traits	trait	NOUN
dpc-3935	19	19	(	(	PUNCT
dpc-3935	19	20	eg	eg	NOUN
dpc-3935	19	21	skin	skin	NOUN
dpc-3935	19	22	color	color	NOUN
dpc-3935	19	23	)	)	PUNCT
dpc-3935	19	24	cause	cause	VERB
dpc-3935	19	25	sporadic	sporadic	ADJ
dpc-3935	19	26	melanoma	melanoma	NOUN
dpc-3935	20	1	[	[	X
dpc-3935	20	2	1	1	NUM
dpc-3935	20	3	]	]	PUNCT
dpc-3935	20	4	.	.	PUNCT
dpc-3935	21	1	approximately	approximately	ADV
dpc-3935	21	2	8	8	NUM
dpc-3935	21	3	%	%	NOUN
dpc-3935	21	4	to	to	PART
dpc-3935	21	5	12	12	NUM
dpc-3935	21	6	%	%	NOUN
dpc-3935	21	7	of	of	ADP
dpc-3935	21	8	patients	patient	NOUN
dpc-3935	21	9	with	with	ADP
dpc-3935	21	10	melanoma	melanoma	NOUN
dpc-3935	21	11	have	have	VERB
dpc-3935	21	12	at	at	ADV
dpc-3935	21	13	least	least	ADJ
dpc-3935	21	14	one	one	NUM
dpc-3935	21	15	first	first	ADJ
dpc-3935	21	16	-	-	PUNCT
dpc-3935	21	17	degree	degree	NOUN
dpc-3935	21	18	relative	relative	NOUN
dpc-3935	21	19	who	who	PRON
dpc-3935	21	20	developed	develop	VERB
dpc-3935	21	21	this	this	DET
dpc-3935	21	22	cancer	cancer	NOUN
dpc-3935	21	23	[	[	X
dpc-3935	21	24	1	1	NUM
dpc-3935	21	25	]	]	PUNCT
dpc-3935	21	26	.	.	PUNCT
dpc-3935	22	1	most	most	ADJ
dpc-3935	22	2	familial	familial	ADJ
dpc-3935	22	3	aggregations	aggregation	NOUN
dpc-3935	22	4	of	of	ADP
dpc-3935	22	5	melanoma	melanoma	NOUN
dpc-3935	22	6	are	be	AUX
dpc-3935	22	7	not	not	PART
dpc-3935	22	8	related	relate	VERB
dpc-3935	22	9	to	to	ADP
dpc-3935	22	10	a	a	DET
dpc-3935	22	11	monogenic	monogenic	ADJ
dpc-3935	22	12	inheritance	inheritance	NOUN
dpc-3935	22	13	.	.	PUNCT
dpc-3935	23	1	they	they	PRON
dpc-3935	23	2	can	can	AUX
dpc-3935	23	3	be	be	AUX
dpc-3935	23	4	associated	associate	VERB
dpc-3935	23	5	with	with	ADP
dpc-3935	23	6	grouping	group	VERB
dpc-3935	23	7	sporadic	sporadic	ADJ
dpc-3935	23	8	cases	case	NOUN
dpc-3935	23	9	in	in	ADP
dpc-3935	23	10	families	family	NOUN
dpc-3935	23	11	with	with	ADP
dpc-3935	23	12	common	common	ADJ
dpc-3935	23	13	risk	risk	NOUN
dpc-3935	23	14	factors	factor	NOUN
dpc-3935	23	15	,	,	PUNCT
dpc-3935	23	16	such	such	ADJ
dpc-3935	23	17	as	as	ADP
dpc-3935	23	18	sun	sun	NOUN
dpc-3935	23	19	exposure	exposure	NOUN
dpc-3935	23	20	or	or	CCONJ
dpc-3935	23	21	fair	fair	ADJ
dpc-3935	23	22	skin	skin	NOUN
dpc-3935	23	23	[	[	X
dpc-3935	23	24	1	1	NUM
dpc-3935	23	25	]	]	PUNCT
dpc-3935	23	26	.	.	PUNCT
dpc-3935	24	1	in	in	ADP
dpc-3935	24	2	up	up	ADP
dpc-3935	24	3	to	to	PART
dpc-3935	24	4	45	45	NUM
dpc-3935	24	5	%	%	NOUN
dpc-3935	24	6	of	of	ADP
dpc-3935	24	7	cases	case	NOUN
dpc-3935	24	8	,	,	PUNCT
dpc-3935	24	9	patients	patient	NOUN
dpc-3935	24	10	with	with	ADP
dpc-3935	24	11	fm	fm	NOUN
dpc-3935	24	12	carry	carry	VERB
dpc-3935	24	13	a	a	DET
dpc-3935	24	14	pv	pv	NOUN
dpc-3935	24	15	in	in	ADP
dpc-3935	24	16	a	a	DET
dpc-3935	24	17	predisposing	predispose	VERB
dpc-3935	24	18	gene	gene	NOUN
dpc-3935	24	19	[	[	X
dpc-3935	24	20	3	3	NUM
dpc-3935	24	21	]	]	PUNCT
dpc-3935	24	22	.	.	PUNCT
dpc-3935	25	1	in	in	ADP
dpc-3935	25	2	this	this	DET
dpc-3935	25	3	context	context	NOUN
dpc-3935	25	4	,	,	PUNCT
dpc-3935	25	5	fewer	few	ADJ
dpc-3935	25	6	somatic	somatic	ADJ
dpc-3935	25	7	acquired	acquire	VERB
dpc-3935	25	8	mutations	mutation	NOUN
dpc-3935	25	9	are	be	AUX
dpc-3935	25	10	likely	likely	ADV
dpc-3935	25	11	required	require	VERB
dpc-3935	25	12	before	before	SCONJ
dpc-3935	25	13	a	a	DET
dpc-3935	25	14	critical	critical	ADJ
dpc-3935	25	15	level	level	NOUN
dpc-3935	25	16	for	for	ADP
dpc-3935	25	17	oncogenesis	oncogenesis	NOUN
dpc-3935	25	18	is	be	AUX
dpc-3935	25	19	achieved	achieve	VERB
dpc-3935	25	20	.	.	PUNCT
dpc-3935	26	1	prevalence	prevalence	NOUN
dpc-3935	26	2	of	of	ADP
dpc-3935	26	3	moderate	moderate	ADJ
dpc-3935	26	4	or	or	CCONJ
dpc-3935	26	5	high	high	ADJ
dpc-3935	26	6	-	-	PUNCT
dpc-3935	26	7	risk	risk	NOUN
dpc-3935	26	8	alleles	allele	NOUN
dpc-3935	26	9	and	and	CCONJ
dpc-3935	26	10	penetrance	penetrance	NOUN
dpc-3935	26	11	of	of	ADP
dpc-3935	26	12	pv	pv	NOUN
dpc-3935	26	13	in	in	ADP
dpc-3935	26	14	these	these	DET
dpc-3935	26	15	genes	gene	NOUN
dpc-3935	26	16	vary	vary	VERB
dpc-3935	26	17	from	from	ADP
dpc-3935	26	18	15	15	NUM
dpc-3935	26	19	%	%	NOUN
dpc-3935	26	20	to	to	PART
dpc-3935	26	21	45	45	NUM
dpc-3935	26	22	%	%	NOUN
dpc-3935	26	23	according	accord	VERB
dpc-3935	26	24	to	to	ADP
dpc-3935	26	25	geographical	geographical	ADJ
dpc-3935	26	26	area	area	NOUN
dpc-3935	26	27	and	and	CCONJ
dpc-3935	26	28	ethnicity	ethnicity	NOUN
dpc-3935	26	29	[	[	X
dpc-3935	26	30	3	3	NUM
dpc-3935	26	31	-	-	SYM
dpc-3935	26	32	7	7	NUM
dpc-3935	26	33	]	]	PUNCT
dpc-3935	26	34	,	,	PUNCT
dpc-3935	26	35	which	which	PRON
dpc-3935	26	36	is	be	AUX
dpc-3935	26	37	likely	likely	ADJ
dpc-3935	26	38	a	a	DET
dpc-3935	26	39	reflection	reflection	NOUN
dpc-3935	26	40	of	of	ADP
dpc-3935	26	41	a	a	DET
dpc-3935	26	42	combination	combination	NOUN
dpc-3935	26	43	of	of	ADP
dpc-3935	26	44	environmental	environmental	ADJ
dpc-3935	26	45	factors	factor	NOUN
dpc-3935	26	46	with	with	ADP
dpc-3935	26	47	several	several	ADJ
dpc-3935	26	48	other	other	ADJ
dpc-3935	26	49	inheritable	inheritable	ADJ
dpc-3935	26	50	genetic	genetic	ADJ
dpc-3935	26	51	modifiers	modifier	NOUN
dpc-3935	26	52	shared	share	VERB
dpc-3935	26	53	by	by	ADP
dpc-3935	26	54	family	family	NOUN
dpc-3935	26	55	members	member	NOUN
dpc-3935	26	56	.	.	PUNCT
dpc-3935	27	1	considering	consider	VERB
dpc-3935	27	2	the	the	DET
dpc-3935	27	3	distribution	distribution	NOUN
dpc-3935	27	4	of	of	ADP
dpc-3935	27	5	polymorphic	polymorphic	ADJ
dpc-3935	27	6	lowrisk	lowrisk	NOUN
dpc-3935	27	7	alleles	allele	NOUN
dpc-3935	27	8	across	across	ADP
dpc-3935	27	9	geographical	geographical	ADJ
dpc-3935	27	10	areas	area	NOUN
dpc-3935	27	11	,	,	PUNCT
dpc-3935	27	12	no	no	DET
dpc-3935	27	13	single	single	ADJ
dpc-3935	27	14	guideline	guideline	NOUN
dpc-3935	27	15	for	for	ADP
dpc-3935	27	16	melanoma	melanoma	NOUN
dpc-3935	27	17	genetic	genetic	ADJ
dpc-3935	27	18	testing	testing	NOUN
dpc-3935	27	19	can	can	AUX
dpc-3935	27	20	be	be	AUX
dpc-3935	27	21	adopted	adopt	VERB
dpc-3935	27	22	worldwide	worldwide	ADV
dpc-3935	27	23	.	.	PUNCT
dpc-3935	28	1	however	however	ADV
dpc-3935	28	2	,	,	PUNCT
dpc-3935	28	3	in	in	ADP
dpc-3935	28	4	southern	southern	ADJ
dpc-3935	28	5	european	european	ADJ
dpc-3935	28	6	populations	population	NOUN
dpc-3935	28	7	,	,	PUNCT
dpc-3935	28	8	where	where	SCONJ
dpc-3935	28	9	the	the	DET
dpc-3935	28	10	incidence	incidence	NOUN
dpc-3935	28	11	of	of	ADP
dpc-3935	28	12	melanoma	melanoma	NOUN
dpc-3935	28	13	is	be	AUX
dpc-3935	28	14	historically	historically	ADV
dpc-3935	28	15	considered	consider	VERB
dpc-3935	28	16	low	low	ADJ
dpc-3935	28	17	,	,	PUNCT
dpc-3935	28	18	genetic	genetic	ADJ
dpc-3935	28	19	testing	testing	NOUN
dpc-3935	28	20	is	be	AUX
dpc-3935	28	21	generally	generally	ADV
dpc-3935	28	22	proposed	propose	VERB
dpc-3935	28	23	in	in	ADP
dpc-3935	28	24	the	the	DET
dpc-3935	28	25	presence	presence	NOUN
dpc-3935	28	26	of	of	ADP
dpc-3935	28	27	melanoma	melanoma	NOUN
dpc-3935	28	28	in	in	ADP
dpc-3935	28	29	at	at	ADV
dpc-3935	28	30	least	least	ADV
dpc-3935	28	31	two	two	NUM
dpc-3935	28	32	first	first	ADJ
dpc-3935	28	33	-	-	PUNCT
dpc-3935	28	34	degree	degree	NOUN
dpc-3935	28	35	relatives	relative	NOUN
dpc-3935	28	36	or	or	CCONJ
dpc-3935	28	37	three	three	NUM
dpc-3935	28	38	second	second	ADJ
dpc-3935	28	39	-	-	PUNCT
dpc-3935	28	40	degree	degree	NOUN
dpc-3935	28	41	relatives	relative	NOUN
dpc-3935	28	42	in	in	ADP
dpc-3935	28	43	the	the	DET
dpc-3935	28	44	same	same	ADJ
dpc-3935	28	45	branch	branch	NOUN
dpc-3935	28	46	of	of	ADP
dpc-3935	28	47	the	the	DET
dpc-3935	28	48	family	family	NOUN
dpc-3935	28	49	[	[	X
dpc-3935	28	50	8	8	NUM
dpc-3935	28	51	]	]	PUNCT
dpc-3935	28	52	.	.	PUNCT
dpc-3935	29	1	since	since	SCONJ
dpc-3935	29	2	the	the	DET
dpc-3935	29	3	mid-1990s	mid-1990	NOUN
dpc-3935	29	4	,	,	PUNCT
dpc-3935	29	5	many	many	ADJ
dpc-3935	29	6	melanoma	melanoma	NOUN
dpc-3935	29	7	predisposition	predisposition	NOUN
dpc-3935	29	8	genes	gene	NOUN
dpc-3935	29	9	have	have	AUX
dpc-3935	29	10	been	be	AUX
dpc-3935	29	11	identified	identify	VERB
dpc-3935	29	12	.	.	PUNCT
dpc-3935	30	1	cdkn2a	cdkn2a	PROPN
dpc-3935	30	2	is	be	AUX
dpc-3935	30	3	involved	involve	VERB
dpc-3935	30	4	in	in	ADP
dpc-3935	30	5	approximately	approximately	ADV
dpc-3935	30	6	20%-40	20%-40	NUM
dpc-3935	30	7	%	%	NOUN
dpc-3935	30	8	of	of	ADP
dpc-3935	30	9	familial	familial	ADJ
dpc-3935	30	10	melanoma	melanoma	NOUN
dpc-3935	30	11	cases	case	NOUN
dpc-3935	30	12	[	[	X
dpc-3935	30	13	9	9	NUM
dpc-3935	30	14	]	]	PUNCT
dpc-3935	30	15	.	.	PUNCT
dpc-3935	31	1	the	the	DET
dpc-3935	31	2	cdkn2a	cdkn2a	PROPN
dpc-3935	31	3	gene	gene	NOUN
dpc-3935	31	4	consists	consist	VERB
dpc-3935	31	5	of	of	ADP
dpc-3935	31	6	three	three	NUM
dpc-3935	31	7	exons	exon	NOUN
dpc-3935	31	8	encoding	encode	VERB
dpc-3935	31	9	two	two	NUM
dpc-3935	31	10	proteins	protein	NOUN
dpc-3935	31	11	derived	derive	VERB
dpc-3935	31	12	from	from	ADP
dpc-3935	31	13	alternatively	alternatively	ADV
dpc-3935	31	14	framed	frame	VERB
dpc-3935	31	15	transcripts	transcript	NOUN
dpc-3935	31	16	,	,	PUNCT
dpc-3935	31	17	p16	p16	NOUN
dpc-3935	31	18	 	 	SPACE
dpc-3935	31	19	(	(	PUNCT
dpc-3935	31	20	p16ink4a	p16ink4a	NUM
dpc-3935	31	21	)	)	PUNCT
dpc-3935	31	22	and	and	CCONJ
dpc-3935	31	23	p14	p14	NOUN
dpc-3935	31	24	(	(	PUNCT
dpc-3935	31	25	p14arf	p14arf	PROPN
dpc-3935	31	26	)	)	PUNCT
dpc-3935	31	27	,	,	PUNCT
dpc-3935	31	28	both	both	PRON
dpc-3935	31	29	acting	act	VERB
dpc-3935	31	30	as	as	ADP
dpc-3935	31	31	a	a	DET
dpc-3935	31	32	tumor	tumor	NOUN
dpc-3935	31	33	suppressor	suppressor	NOUN
dpc-3935	31	34	involved	involve	VERB
dpc-3935	31	35	in	in	ADP
dpc-3935	31	36	cell	cell	NOUN
dpc-3935	31	37	cycle	cycle	NOUN
dpc-3935	31	38	control	control	NOUN
dpc-3935	31	39	.	.	PUNCT
dpc-3935	32	1	genome	genome	NOUN
dpc-3935	32	2	-	-	PUNCT
dpc-3935	32	3	wide	wide	ADJ
dpc-3935	32	4	dna	dna	NOUN
dpc-3935	32	5	sequencing	sequence	VERB
dpc-3935	32	6	studies	study	NOUN
dpc-3935	32	7	have	have	AUX
dpc-3935	32	8	demonstrated	demonstrate	VERB
dpc-3935	32	9	that	that	SCONJ
dpc-3935	32	10	the	the	DET
dpc-3935	32	11	cdkn2a	cdkn2a	PROPN
dpc-3935	32	12	locus	locus	NOUN
dpc-3935	32	13	is	be	AUX
dpc-3935	32	14	in	in	ADP
dpc-3935	32	15	a	a	DET
dpc-3935	32	16	nevus	nevus	NOUN
dpc-3935	32	17	-	-	PUNCT
dpc-3935	32	18	associated	associate	VERB
dpc-3935	32	19	genomic	genomic	NOUN
dpc-3935	32	20	region	region	NOUN
dpc-3935	32	21	.	.	PUNCT
dpc-3935	33	1	carriers	carrier	NOUN
dpc-3935	33	2	of	of	ADP
dpc-3935	33	3	cdkn2a	cdkn2a	PROPN
dpc-3935	33	4	pv	pv	PROPN
dpc-3935	33	5	show	show	VERB
dpc-3935	33	6	a	a	DET
dpc-3935	33	7	significantly	significantly	ADV
dpc-3935	33	8	higher	high	ADJ
dpc-3935	33	9	number	number	NOUN
dpc-3935	33	10	of	of	ADP
dpc-3935	33	11	nevi	nevi	ADJ
dpc-3935	33	12	and	and	CCONJ
dpc-3935	33	13	clinically	clinically	ADV
dpc-3935	33	14	atypical	atypical	ADJ
dpc-3935	33	15	nevi	nevi	NOUN
dpc-3935	33	16	than	than	ADP
dpc-3935	33	17	non	non	NOUN
dpc-3935	33	18	-	-	NOUN
dpc-3935	33	19	carriers	carrier	NOUN
dpc-3935	33	20	[	[	X
dpc-3935	33	21	10	10	NUM
dpc-3935	33	22	,	,	PUNCT
dpc-3935	33	23	11	11	NUM
dpc-3935	33	24	]	]	PUNCT
dpc-3935	33	25	.	.	PUNCT
dpc-3935	34	1	some	some	PRON
dpc-3935	34	2	,	,	PUNCT
dpc-3935	34	3	but	but	CCONJ
dpc-3935	34	4	not	not	PART
dpc-3935	34	5	all	all	PRON
dpc-3935	34	6	,	,	PUNCT
dpc-3935	34	7	cdkn2a	cdkn2a	X
dpc-3935	34	8	carriers	carrier	NOUN
dpc-3935	34	9	exhibit	exhibit	VERB
dpc-3935	34	10	a	a	DET
dpc-3935	34	11	clinical	clinical	ADJ
dpc-3935	34	12	phenotype	phenotype	NOUN
dpc-3935	34	13	consistent	consistent	ADJ
dpc-3935	34	14	with	with	ADP
dpc-3935	34	15	atypical	atypical	ADJ
dpc-3935	34	16	multiple	multiple	ADJ
dpc-3935	34	17	mole	mole	NOUN
dpc-3935	34	18	melanoma	melanoma	NOUN
dpc-3935	34	19	syndromes	syndrome	NOUN
dpc-3935	34	20	(	(	PUNCT
dpc-3935	34	21	fammm	fammm	NOUN
dpc-3935	34	22	)	)	PUNCT
dpc-3935	35	1	[	[	X
dpc-3935	35	2	5,12,13	5,12,13	NUM
dpc-3935	35	3	]	]	PUNCT
dpc-3935	35	4	.	.	PUNCT
dpc-3935	36	1	the	the	DET
dpc-3935	36	2	detection	detection	NOUN
dpc-3935	36	3	rate	rate	NOUN
dpc-3935	36	4	of	of	ADP
dpc-3935	36	5	cdkn2a	cdkn2a	PROPN
dpc-3935	36	6	pv	pv	PROPN
dpc-3935	36	7	varies	vary	VERB
dpc-3935	36	8	across	across	ADP
dpc-3935	36	9	different	different	ADJ
dpc-3935	36	10	geographical	geographical	ADJ
dpc-3935	36	11	areas	area	NOUN
dpc-3935	36	12	[	[	X
dpc-3935	36	13	4	4	NUM
dpc-3935	36	14	]	]	PUNCT
dpc-3935	36	15	.	.	PUNCT
dpc-3935	37	1	in	in	ADP
dpc-3935	37	2	2009	2009	NUM
dpc-3935	37	3	,	,	PUNCT
dpc-3935	37	4	cdkn2a	cdkn2a	PROPN
dpc-3935	37	5	pv	pv	INTJ
dpc-3935	37	6	were	be	AUX
dpc-3935	37	7	identified	identify	VERB
dpc-3935	37	8	in	in	ADP
dpc-3935	37	9	about	about	ADV
dpc-3935	37	10	33	33	NUM
dpc-3935	37	11	%	%	NOUN
dpc-3935	37	12	of	of	ADP
dpc-3935	37	13	fm	fm	PROPN
dpc-3935	37	14	cases	case	NOUN
dpc-3935	37	15	in	in	ADP
dpc-3935	37	16	italy	italy	PROPN
dpc-3935	37	17	and	and	CCONJ
dpc-3935	37	18	25	25	NUM
dpc-3935	37	19	%	%	NOUN
dpc-3935	37	20	of	of	ADP
dpc-3935	37	21	families	family	NOUN
dpc-3935	37	22	with	with	ADP
dpc-3935	37	23	only	only	ADV
dpc-3935	37	24	two	two	NUM
dpc-3935	37	25	affected	affected	ADJ
dpc-3935	37	26	first	first	ADJ
dpc-3935	37	27	-	-	PUNCT
dpc-3935	37	28	degree	degree	NOUN
dpc-3935	37	29	relatives	relative	NOUN
dpc-3935	37	30	[	[	X
dpc-3935	37	31	13	13	NUM
dpc-3935	37	32	]	]	PUNCT
dpc-3935	37	33	.	.	PUNCT
dpc-3935	38	1	recently	recently	ADV
dpc-3935	38	2	,	,	PUNCT
dpc-3935	38	3	a	a	DET
dpc-3935	38	4	large	large	ADJ
dpc-3935	38	5	multicentric	multicentric	ADJ
dpc-3935	38	6	italian	italian	ADJ
dpc-3935	38	7	study	study	NOUN
dpc-3935	38	8	showed	show	VERB
dpc-3935	38	9	a	a	DET
dpc-3935	38	10	lower	low	ADJ
dpc-3935	38	11	detection	detection	NOUN
dpc-3935	38	12	rate	rate	NOUN
dpc-3935	38	13	,	,	PUNCT
dpc-3935	38	14	identifying	identify	VERB
dpc-3935	38	15	21	21	NUM
dpc-3935	38	16	carriers	carrier	NOUN
dpc-3935	38	17	of	of	ADP
dpc-3935	38	18	cdkn2a	cdkn2a	PROPN
dpc-3935	38	19	pv	pv	ADV
dpc-3935	38	20	out	out	ADP
dpc-3935	38	21	of	of	ADP
dpc-3935	38	22	373	373	NUM
dpc-3935	38	23	melanoma	melanoma	NOUN
dpc-3935	38	24	patients	patient	NOUN
dpc-3935	38	25	having	have	VERB
dpc-3935	38	26	one	one	NUM
dpc-3935	38	27	first	first	ADJ
dpc-3935	38	28	-	-	PUNCT
dpc-3935	38	29	degree	degree	NOUN
dpc-3935	38	30	relative	relative	NOUN
dpc-3935	38	31	with	with	ADP
dpc-3935	38	32	melanoma	melanoma	NOUN
dpc-3935	38	33	(	(	PUNCT
dpc-3935	38	34	5.63	5.63	NUM
dpc-3935	38	35	%	%	NOUN
dpc-3935	38	36	)	)	PUNCT
dpc-3935	38	37	and	and	CCONJ
dpc-3935	38	38	ten	ten	NUM
dpc-3935	38	39	carriers	carrier	NOUN
dpc-3935	38	40	out	out	ADP
dpc-3935	38	41	of	of	ADP
dpc-3935	38	42	101	101	NUM
dpc-3935	38	43	patients	patient	NOUN
dpc-3935	38	44	with	with	ADP
dpc-3935	38	45	two	two	NUM
dpc-3935	38	46	first	first	ADJ
dpc-3935	38	47	-	-	PUNCT
dpc-3935	38	48	degree	degree	NOUN
dpc-3935	38	49	relatives	relative	NOUN
dpc-3935	38	50	(	(	PUNCT
dpc-3935	38	51	9.9	9.9	NUM
dpc-3935	38	52	%	%	NOUN
dpc-3935	38	53	)	)	PUNCT
dpc-3935	39	1	[	[	X
dpc-3935	39	2	14	14	NUM
dpc-3935	39	3	]	]	PUNCT
dpc-3935	39	4	.	.	PUNCT
dpc-3935	40	1	increasing	increase	VERB
dpc-3935	40	2	evidence	evidence	NOUN
dpc-3935	40	3	suggests	suggest	VERB
dpc-3935	40	4	melanoma	melanoma	NOUN
dpc-3935	40	5	is	be	AUX
dpc-3935	40	6	part	part	NOUN
dpc-3935	40	7	of	of	ADP
dpc-3935	40	8	larger	large	ADJ
dpc-3935	40	9	cancer	cancer	NOUN
dpc-3935	40	10	syndromes	syndrome	NOUN
dpc-3935	41	1	[	[	X
dpc-3935	41	2	9	9	NUM
dpc-3935	41	3	]	]	PUNCT
dpc-3935	41	4	.	.	PUNCT
dpc-3935	42	1	cdkn2a	cdkn2a	PROPN
dpc-3935	42	2	pv	pv	INTJ
dpc-3935	43	1	affecting	affect	VERB
dpc-3935	43	2	p16ink4a	p16ink4a	NOUN
dpc-3935	43	3	are	be	AUX
dpc-3935	43	4	associated	associate	VERB
dpc-3935	43	5	with	with	ADP
dpc-3935	43	6	an	an	DET
dpc-3935	43	7	increased	increase	VERB
dpc-3935	43	8	risk	risk	NOUN
dpc-3935	43	9	of	of	ADP
dpc-3935	43	10	developing	develop	VERB
dpc-3935	43	11	pancreatic	pancreatic	ADJ
dpc-3935	43	12	cancer	cancer	NOUN
dpc-3935	43	13	(	(	PUNCT
dpc-3935	43	14	pc	pc	NOUN
dpc-3935	43	15	)	)	PUNCT
dpc-3935	43	16	,	,	PUNCT
dpc-3935	43	17	up	up	ADP
dpc-3935	43	18	to	to	PART
dpc-3935	43	19	20	20	NUM
dpc-3935	43	20	%	%	NOUN
dpc-3935	43	21	within	within	ADP
dpc-3935	43	22	the	the	DET
dpc-3935	43	23	age	age	NOUN
dpc-3935	43	24	of	of	ADP
dpc-3935	43	25	70	70	NUM
dpc-3935	44	1	[	[	X
dpc-3935	44	2	15,16	15,16	NUM
dpc-3935	44	3	]	]	PUNCT
dpc-3935	44	4	.	.	PUNCT
dpc-3935	45	1	pv	pv	INTJ
dpc-3935	45	2	in	in	ADP
dpc-3935	45	3	other	other	ADJ
dpc-3935	45	4	genes	gene	NOUN
dpc-3935	45	5	such	such	ADJ
dpc-3935	45	6	as	as	ADP
dpc-3935	45	7	cdk4	cdk4	NOUN
dpc-3935	45	8	,	,	PUNCT
dpc-3935	45	9	pot1	pot1	PROPN
dpc-3935	45	10	,	,	PUNCT
dpc-3935	45	11	bap1	bap1	PROPN
dpc-3935	45	12	,	,	PUNCT
dpc-3935	45	13	mitf	mitf	NOUN
dpc-3935	45	14	,	,	PUNCT
dpc-3935	45	15	atm	atm	NOUN
dpc-3935	45	16	and	and	CCONJ
dpc-3935	45	17	tert	tert	NOUN
dpc-3935	45	18	have	have	AUX
dpc-3935	45	19	been	be	AUX
dpc-3935	45	20	associated	associate	VERB
dpc-3935	45	21	to	to	PART
dpc-3935	45	22	moderate	moderate	VERB
dpc-3935	45	23	to	to	PART
dpc-3935	45	24	highrisk	highrisk	VERB
dpc-3935	45	25	to	to	PART
dpc-3935	45	26	develop	develop	VERB
dpc-3935	45	27	melanoma	melanoma	NOUN
dpc-3935	45	28	,	,	PUNCT
dpc-3935	45	29	as	as	ADV
dpc-3935	45	30	well	well	ADV
dpc-3935	45	31	as	as	ADP
dpc-3935	45	32	other	other	ADJ
dpc-3935	45	33	malignancies	malignancy	NOUN
dpc-3935	45	34	,	,	PUNCT
dpc-3935	45	35	and	and	CCONJ
dpc-3935	45	36	are	be	AUX
dpc-3935	45	37	part	part	NOUN
dpc-3935	45	38	of	of	ADP
dpc-3935	45	39	multi	multi	ADJ
dpc-3935	45	40	-	-	ADJ
dpc-3935	45	41	gene	gene	ADJ
dpc-3935	45	42	panels	panel	NOUN
dpc-3935	45	43	employed	employ	VERB
dpc-3935	45	44	in	in	ADP
dpc-3935	45	45	clinic	clinic	NOUN
dpc-3935	45	46	to	to	PART
dpc-3935	45	47	assess	assess	VERB
dpc-3935	45	48	the	the	DET
dpc-3935	45	49	presence	presence	NOUN
dpc-3935	45	50	of	of	ADP
dpc-3935	45	51	an	an	DET
dpc-3935	45	52	inherited	inherit	VERB
dpc-3935	45	53	melanoma	melanoma	NOUN
dpc-3935	45	54	predisposition	predisposition	NOUN
dpc-3935	45	55	syndrome	syndrome	NOUN
dpc-3935	46	1	[	[	X
dpc-3935	46	2	3,8,17	3,8,17	NUM
dpc-3935	46	3	]	]	PUNCT
dpc-3935	46	4	.	.	PUNCT
dpc-3935	47	1	the	the	DET
dpc-3935	47	2	prevalence	prevalence	NOUN
dpc-3935	47	3	of	of	ADP
dpc-3935	47	4	pv	pv	NOUN
dpc-3935	47	5	in	in	ADP
dpc-3935	47	6	these	these	DET
dpc-3935	47	7	genes	gene	NOUN
dpc-3935	47	8	in	in	ADP
dpc-3935	47	9	italy	italy	PROPN
dpc-3935	47	10	is	be	AUX
dpc-3935	47	11	as	as	ADV
dpc-3935	47	12	high	high	ADJ
dpc-3935	47	13	as	as	ADP
dpc-3935	47	14	3.7	3.7	NUM
dpc-3935	47	15	%	%	NOUN
dpc-3935	47	16	in	in	ADP
dpc-3935	47	17	families	family	NOUN
dpc-3935	47	18	with	with	ADP
dpc-3935	47	19	at	at	ADV
dpc-3935	47	20	least	least	ADV
dpc-3935	47	21	two	two	NUM
dpc-3935	47	22	first	first	ADJ
dpc-3935	47	23	-	-	PUNCT
dpc-3935	47	24	degree	degree	NOUN
dpc-3935	47	25	relatives	relative	NOUN
dpc-3935	47	26	with	with	ADP
dpc-3935	47	27	melanoma	melanoma	NOUN
dpc-3935	47	28	and	and	CCONJ
dpc-3935	47	29	4	4	NUM
dpc-3935	47	30	%	%	NOUN
dpc-3935	47	31	with	with	ADP
dpc-3935	47	32	three	three	NUM
dpc-3935	47	33	affected	affected	ADJ
dpc-3935	47	34	first	first	ADJ
dpc-3935	47	35	-	-	PUNCT
dpc-3935	47	36	degree	degree	NOUN
dpc-3935	47	37	relatives	relative	NOUN
dpc-3935	47	38	[	[	X
dpc-3935	47	39	14	14	NUM
dpc-3935	47	40	]	]	PUNCT
dpc-3935	47	41	.	.	PUNCT
dpc-3935	48	1	objectives	objective	VERB
dpc-3935	48	2	this	this	DET
dpc-3935	48	3	study	study	NOUN
dpc-3935	48	4	aims	aim	VERB
dpc-3935	48	5	to	to	PART
dpc-3935	48	6	estimate	estimate	VERB
dpc-3935	48	7	the	the	DET
dpc-3935	48	8	prevalence	prevalence	NOUN
dpc-3935	48	9	of	of	ADP
dpc-3935	48	10	germline	germline	NOUN
dpc-3935	48	11	pv	pv	VERB
dpc-3935	48	12	in	in	ADP
dpc-3935	48	13	cdkn2a	cdkn2a	PROPN
dpc-3935	48	14	,	,	PUNCT
dpc-3935	48	15	cdk4	cdk4	NOUN
dpc-3935	48	16	,	,	PUNCT
dpc-3935	48	17	pot1	pot1	PROPN
dpc-3935	48	18	,	,	PUNCT
dpc-3935	48	19	bap1	bap1	PROPN
dpc-3935	48	20	,	,	PUNCT
dpc-3935	48	21	mitf	mitf	NOUN
dpc-3935	48	22	,	,	PUNCT
dpc-3935	48	23	atm	atm	ADJ
dpc-3935	48	24	,	,	PUNCT
dpc-3935	48	25	and	and	CCONJ
dpc-3935	48	26	tert	tert	NOUN
dpc-3935	48	27	and	and	CCONJ
dpc-3935	48	28	to	to	PART
dpc-3935	48	29	evaluate	evaluate	VERB
dpc-3935	48	30	the	the	DET
dpc-3935	48	31	impact	impact	NOUN
dpc-3935	48	32	of	of	ADP
dpc-3935	48	33	patient	patient	NOUN
dpc-3935	48	34	’s	’s	PART
dpc-3935	48	35	cutaneous	cutaneous	ADJ
dpc-3935	48	36	phenotype	phenotype	NOUN
dpc-3935	48	37	and	and	CCONJ
dpc-3935	48	38	personal	personal	ADJ
dpc-3935	48	39	/	/	SYM
dpc-3935	48	40	family	family	NOUN
dpc-3935	48	41	history	history	NOUN
dpc-3935	48	42	of	of	ADP
dpc-3935	48	43	pc	pc	NOUN
dpc-3935	48	44	and	and	CCONJ
dpc-3935	48	45	melanomas	melanomas	NOUN
dpc-3935	48	46	as	as	ADP
dpc-3935	48	47	results	result	NOUN
dpc-3935	48	48	:	:	PUNCT
dpc-3935	48	49	during	during	ADP
dpc-3935	48	50	the	the	DET
dpc-3935	48	51	study	study	NOUN
dpc-3935	48	52	period	period	NOUN
dpc-3935	48	53	,	,	PUNCT
dpc-3935	48	54	35	35	NUM
dpc-3935	48	55	out	out	ADP
dpc-3935	48	56	of	of	ADP
dpc-3935	48	57	1320	1320	NUM
dpc-3935	48	58	patients	patient	NOUN
dpc-3935	48	59	(	(	PUNCT
dpc-3935	48	60	2.7	2.7	NUM
dpc-3935	48	61	%	%	NOUN
dpc-3935	48	62	)	)	PUNCT
dpc-3935	48	63	underwent	underwent	ADJ
dpc-3935	48	64	genetic	genetic	ADJ
dpc-3935	48	65	testing	testing	NOUN
dpc-3935	48	66	.	.	PUNCT
dpc-3935	49	1	four	four	NUM
dpc-3935	49	2	patients	patient	NOUN
dpc-3935	49	3	(	(	PUNCT
dpc-3935	49	4	11.4	11.4	NUM
dpc-3935	49	5	%	%	NOUN
dpc-3935	49	6	)	)	PUNCT
dpc-3935	49	7	harbored	harbor	VERB
dpc-3935	49	8	a	a	DET
dpc-3935	49	9	pv	pv	NOUN
dpc-3935	49	10	in	in	ADP
dpc-3935	49	11	a	a	DET
dpc-3935	49	12	melanoma	melanoma	NOUN
dpc-3935	49	13	-	-	PUNCT
dpc-3935	49	14	predisposing	predispose	VERB
dpc-3935	49	15	gene	gene	NOUN
dpc-3935	49	16	,	,	PUNCT
dpc-3935	49	17	three	three	NUM
dpc-3935	49	18	in	in	ADP
dpc-3935	49	19	cdkn2a	cdkn2a	PROPN
dpc-3935	49	20	(	(	PUNCT
dpc-3935	49	21	8.6	8.6	NUM
dpc-3935	49	22	%	%	NOUN
dpc-3935	49	23	)	)	PUNCT
dpc-3935	49	24	,	,	PUNCT
dpc-3935	49	25	and	and	CCONJ
dpc-3935	49	26	one	one	NUM
dpc-3935	49	27	in	in	ADP
dpc-3935	49	28	mitf	mitf	NOUN
dpc-3935	49	29	(	(	PUNCT
dpc-3935	49	30	2.9	2.9	NUM
dpc-3935	49	31	%	%	NOUN
dpc-3935	49	32	)	)	PUNCT
dpc-3935	49	33	.	.	PUNCT
dpc-3935	50	1	variants	variant	NOUN
dpc-3935	50	2	currently	currently	ADV
dpc-3935	50	3	classified	classify	VERB
dpc-3935	50	4	as	as	ADP
dpc-3935	50	5	being	be	AUX
dpc-3935	50	6	of	of	ADP
dpc-3935	50	7	unknown	unknown	ADJ
dpc-3935	50	8	clinical	clinical	ADJ
dpc-3935	50	9	significance	significance	NOUN
dpc-3935	50	10	(	(	PUNCT
dpc-3935	50	11	vus	vus	NOUN
dpc-3935	50	12	)	)	PUNCT
dpc-3935	50	13	were	be	AUX
dpc-3935	50	14	detected	detect	VERB
dpc-3935	50	15	in	in	ADP
dpc-3935	50	16	cdkn2a	cdkn2a	PROPN
dpc-3935	50	17	(	(	PUNCT
dpc-3935	50	18	n	n	NOUN
dpc-3935	50	19	=	=	SYM
dpc-3935	50	20	1	1	NUM
dpc-3935	50	21	)	)	PUNCT
dpc-3935	50	22	,	,	PUNCT
dpc-3935	50	23	mitf	mitf	NOUN
dpc-3935	50	24	(	(	PUNCT
dpc-3935	50	25	n	n	NOUN
dpc-3935	50	26	=	=	SYM
dpc-3935	50	27	1	1	NUM
dpc-3935	50	28	)	)	PUNCT
dpc-3935	50	29	,	,	PUNCT
dpc-3935	50	30	and	and	CCONJ
dpc-3935	50	31	atm	atm	NOUN
dpc-3935	50	32	(	(	PUNCT
dpc-3935	50	33	n	n	NOUN
dpc-3935	50	34	=	=	SYM
dpc-3935	50	35	2	2	NUM
dpc-3935	50	36	)	)	PUNCT
dpc-3935	50	37	.	.	PUNCT
dpc-3935	51	1	family	family	NOUN
dpc-3935	51	2	history	history	NOUN
dpc-3935	51	3	of	of	ADP
dpc-3935	51	4	pc	pc	NOUN
dpc-3935	51	5	and	and	CCONJ
dpc-3935	51	6	≥5	≥5	NUM
dpc-3935	51	7	melanomas	melanoma	NOUN
dpc-3935	51	8	,	,	PUNCT
dpc-3935	51	9	personal	personal	ADJ
dpc-3935	51	10	history	history	NOUN
dpc-3935	51	11	of	of	ADP
dpc-3935	51	12	≥50	≥50	ADJ
dpc-3935	51	13	nevi	nevi	ADJ
dpc-3935	51	14	,	,	PUNCT
dpc-3935	51	15	and	and	CCONJ
dpc-3935	51	16	≥4	≥4	PROPN
dpc-3935	51	17	melanomas	melanoma	NOUN
dpc-3935	51	18	were	be	AUX
dpc-3935	51	19	significantly	significantly	ADV
dpc-3935	51	20	associated	associate	VERB
dpc-3935	51	21	with	with	ADP
dpc-3935	51	22	pv	pv	NOUN
dpc-3935	51	23	in	in	ADP
dpc-3935	51	24	tested	test	VERB
dpc-3935	51	25	genes	gene	NOUN
dpc-3935	51	26	(	(	PUNCT
dpc-3935	51	27	p	p	X
dpc-3935	51	28	<	<	X
dpc-3935	51	29	0.05	0.05	NUM
dpc-3935	51	30	)	)	PUNCT
dpc-3935	51	31	.	.	PUNCT
dpc-3935	52	1	conclusions	conclusion	NOUN
dpc-3935	52	2	:	:	PUNCT
dpc-3935	52	3	the	the	DET
dpc-3935	52	4	prevalence	prevalence	NOUN
dpc-3935	52	5	of	of	ADP
dpc-3935	52	6	pv	pv	NOUN
dpc-3935	52	7	in	in	ADP
dpc-3935	52	8	predisposing	predispose	VERB
dpc-3935	52	9	genes	gene	NOUN
dpc-3935	52	10	in	in	ADP
dpc-3935	52	11	fm	fm	PROPN
dpc-3935	52	12	was	be	AUX
dpc-3935	52	13	lower	low	ADJ
dpc-3935	52	14	than	than	SCONJ
dpc-3935	52	15	previously	previously	ADV
dpc-3935	52	16	reported	report	VERB
dpc-3935	52	17	in	in	ADP
dpc-3935	52	18	italian	italian	ADJ
dpc-3935	52	19	registries	registry	NOUN
dpc-3935	52	20	.	.	PUNCT
dpc-3935	53	1	possible	possible	ADJ
dpc-3935	53	2	reasons	reason	NOUN
dpc-3935	53	3	include	include	VERB
dpc-3935	53	4	deleterious	deleterious	ADJ
dpc-3935	53	5	variants	variant	NOUN
dpc-3935	53	6	in	in	ADP
dpc-3935	53	7	untested	untested	ADJ
dpc-3935	53	8	intermediate	intermediate	ADJ
dpc-3935	53	9	/	/	SYM
dpc-3935	53	10	low	low	ADJ
dpc-3935	53	11	-	-	PUNCT
dpc-3935	53	12	penetrance	penetrance	NOUN
dpc-3935	53	13	genes	gene	NOUN
dpc-3935	53	14	or	or	CCONJ
dpc-3935	53	15	yet	yet	ADV
dpc-3935	53	16	-	-	PUNCT
dpc-3935	53	17	to	to	PART
dpc-3935	53	18	-	-	PUNCT
dpc-3935	53	19	be	be	AUX
dpc-3935	53	20	-	-	PUNCT
dpc-3935	53	21	discovered	discover	VERB
dpc-3935	53	22	high	high	ADJ
dpc-3935	53	23	-	-	PUNCT
dpc-3935	53	24	penetrance	penetrance	NOUN
dpc-3935	53	25	genes	gene	NOUN
dpc-3935	53	26	and	and	CCONJ
dpc-3935	53	27	environmental	environmental	ADJ
dpc-3935	53	28	risk	risk	NOUN
dpc-3935	53	29	factors	factor	NOUN
dpc-3935	53	30	.	.	PUNCT
dpc-3935	54	1	a	a	DET
dpc-3935	54	2	family	family	NOUN
dpc-3935	54	3	history	history	NOUN
dpc-3935	54	4	of	of	ADP
dpc-3935	54	5	pc	pc	NOUN
dpc-3935	54	6	,	,	PUNCT
dpc-3935	54	7	a	a	DET
dpc-3935	54	8	high	high	ADJ
dpc-3935	54	9	number	number	NOUN
dpc-3935	54	10	of	of	ADP
dpc-3935	54	11	nevi	nevi	ADJ
dpc-3935	54	12	and	and	CCONJ
dpc-3935	54	13	melanomas	melanomas	PROPN
dpc-3935	54	14	predict	predict	VERB
dpc-3935	54	15	a	a	DET
dpc-3935	54	16	monogenic	monogenic	ADJ
dpc-3935	54	17	predisposition	predisposition	NOUN
dpc-3935	54	18	to	to	ADP
dpc-3935	54	19	melanoma	melanoma	VERB
dpc-3935	54	20	.	.	PUNCT
dpc-3935	55	1	original	original	ADJ
dpc-3935	55	2	article	article	NOUN
dpc-3935	55	3	|	|	ADV
dpc-3935	55	4	dermatol	dermatol	ADJ
dpc-3935	55	5	pract	pract	NOUN
dpc-3935	55	6	concept	concept	NOUN
dpc-3935	55	7	.	.	PUNCT
dpc-3935	56	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	56	2	3	3	NUM
dpc-3935	56	3	predictors	predictor	NOUN
dpc-3935	56	4	of	of	ADP
dpc-3935	56	5	the	the	DET
dpc-3935	56	6	presence	presence	NOUN
dpc-3935	56	7	of	of	ADP
dpc-3935	56	8	a	a	DET
dpc-3935	56	9	monogenic	monogenic	ADJ
dpc-3935	56	10	predisposition	predisposition	NOUN
dpc-3935	56	11	in	in	ADP
dpc-3935	56	12	a	a	DET
dpc-3935	56	13	single	single	ADJ
dpc-3935	56	14	-	-	PUNCT
dpc-3935	56	15	center	center	NOUN
dpc-3935	56	16	cohort	cohort	NOUN
dpc-3935	56	17	of	of	ADP
dpc-3935	56	18	highly	highly	ADV
dpc-3935	56	19	selected	select	VERB
dpc-3935	56	20	italian	italian	ADJ
dpc-3935	56	21	melanoma	melanoma	NOUN
dpc-3935	56	22	patients	patient	NOUN
dpc-3935	56	23	.	.	PUNCT
dpc-3935	57	1	taking	take	VERB
dpc-3935	57	2	into	into	ADP
dpc-3935	57	3	account	account	NOUN
dpc-3935	57	4	the	the	DET
dpc-3935	57	5	rising	rise	VERB
dpc-3935	57	6	of	of	ADP
dpc-3935	57	7	melanoma	melanoma	NOUN
dpc-3935	57	8	incidence	incidence	NOUN
dpc-3935	57	9	and	and	CCONJ
dpc-3935	57	10	the	the	DET
dpc-3935	57	11	recent	recent	ADJ
dpc-3935	57	12	decrease	decrease	NOUN
dpc-3935	57	13	in	in	ADP
dpc-3935	57	14	the	the	DET
dpc-3935	57	15	prevalence	prevalence	NOUN
dpc-3935	57	16	of	of	ADP
dpc-3935	57	17	pv	pv	NOUN
dpc-3935	57	18	among	among	ADP
dpc-3935	57	19	fm	fm	NOUN
dpc-3935	57	20	and	and	CCONJ
dpc-3935	57	21	multiple	multiple	ADJ
dpc-3935	57	22	primary	primary	ADJ
dpc-3935	57	23	melanoma	melanoma	NOUN
dpc-3935	57	24	cases	case	NOUN
dpc-3935	57	25	in	in	ADP
dpc-3935	57	26	italy	italy	PROPN
dpc-3935	57	27	,	,	PUNCT
dpc-3935	57	28	to	to	PART
dpc-3935	57	29	select	select	VERB
dpc-3935	57	30	the	the	DET
dpc-3935	57	31	study	study	NOUN
dpc-3935	57	32	population	population	NOUN
dpc-3935	57	33	we	we	PRON
dpc-3935	57	34	employed	employ	VERB
dpc-3935	57	35	criteria	criterion	NOUN
dpc-3935	57	36	that	that	PRON
dpc-3935	57	37	are	be	AUX
dpc-3935	57	38	more	more	ADV
dpc-3935	57	39	stringent	stringent	ADJ
dpc-3935	57	40	than	than	ADP
dpc-3935	57	41	those	those	PRON
dpc-3935	57	42	used	use	VERB
dpc-3935	57	43	in	in	ADP
dpc-3935	57	44	the	the	DET
dpc-3935	57	45	current	current	ADJ
dpc-3935	57	46	clinical	clinical	ADJ
dpc-3935	57	47	practice	practice	NOUN
dpc-3935	57	48	to	to	PART
dpc-3935	57	49	propose	propose	VERB
dpc-3935	57	50	genetic	genetic	ADJ
dpc-3935	57	51	counseling	counseling	NOUN
dpc-3935	57	52	and	and	CCONJ
dpc-3935	57	53	testing	testing	NOUN
dpc-3935	57	54	in	in	ADP
dpc-3935	57	55	italy	italy	PROPN
dpc-3935	57	56	(	(	PUNCT
dpc-3935	57	57	italian	italian	ADJ
dpc-3935	57	58	societies	society	NOUN
dpc-3935	57	59	such	such	ADJ
dpc-3935	57	60	as	as	ADP
dpc-3935	57	61	italian	italian	ADJ
dpc-3935	57	62	society	society	NOUN
dpc-3935	57	63	of	of	ADP
dpc-3935	57	64	human	human	ADJ
dpc-3935	57	65	genetics	genetic	NOUN
dpc-3935	57	66	(	(	PUNCT
dpc-3935	57	67	sigu	sigu	ADV
dpc-3935	57	68	)	)	PUNCT
dpc-3935	58	1	[	[	X
dpc-3935	58	2	18	18	NUM
dpc-3935	58	3	]	]	PUNCT
dpc-3935	58	4	,	,	PUNCT
dpc-3935	58	5	italian	italian	ADJ
dpc-3935	58	6	society	society	NOUN
dpc-3935	58	7	of	of	ADP
dpc-3935	58	8	dermatology	dermatology	NOUN
dpc-3935	58	9	(	(	PUNCT
dpc-3935	58	10	sidemast	sidemast	NOUN
dpc-3935	58	11	)	)	PUNCT
dpc-3935	59	1	[	[	X
dpc-3935	59	2	19	19	NUM
dpc-3935	59	3	]	]	PUNCT
dpc-3935	59	4	and	and	CCONJ
dpc-3935	59	5	italian	italian	ADJ
dpc-3935	59	6	society	society	NOUN
dpc-3935	59	7	of	of	ADP
dpc-3935	59	8	oncology	oncology	NOUN
dpc-3935	59	9	(	(	PUNCT
dpc-3935	59	10	aiom	aiom	ADJ
dpc-3935	59	11	)	)	PUNCT
dpc-3935	60	1	[	[	X
dpc-3935	60	2	20	20	NUM
dpc-3935	60	3	]	]	NUM
dpc-3935	60	4	)	)	PUNCT
dpc-3935	60	5	.	.	PUNCT
dpc-3935	61	1	methods	method	NOUN
dpc-3935	61	2	study	study	VERB
dpc-3935	61	3	population	population	NOUN
dpc-3935	61	4	and	and	CCONJ
dpc-3935	61	5	ethics	ethic	NOUN
dpc-3935	61	6	statement	statement	NOUN
dpc-3935	61	7	medical	medical	ADJ
dpc-3935	61	8	records	record	NOUN
dpc-3935	61	9	of	of	ADP
dpc-3935	61	10	1320	1320	NUM
dpc-3935	61	11	patients	patient	NOUN
dpc-3935	61	12	diagnosed	diagnose	VERB
dpc-3935	61	13	with	with	ADP
dpc-3935	61	14	cutaneous	cutaneous	ADJ
dpc-3935	61	15	melanoma	melanoma	NOUN
dpc-3935	61	16	at	at	ADP
dpc-3935	61	17	the	the	DET
dpc-3935	61	18	dermatology	dermatology	NOUN
dpc-3935	61	19	unit	unit	NOUN
dpc-3935	61	20	of	of	ADP
dpc-3935	61	21	the	the	DET
dpc-3935	61	22	university	university	PROPN
dpc-3935	61	23	of	of	ADP
dpc-3935	61	24	verona	verona	PROPN
dpc-3935	61	25	hospital	hospital	PROPN
dpc-3935	61	26	trust	trust	PROPN
dpc-3935	61	27	,	,	PUNCT
dpc-3935	61	28	verona	verona	PROPN
dpc-3935	61	29	,	,	PUNCT
dpc-3935	61	30	italy	italy	PROPN
dpc-3935	61	31	,	,	PUNCT
dpc-3935	61	32	from	from	ADP
dpc-3935	61	33	april	april	PROPN
dpc-3935	61	34	2000	2000	NUM
dpc-3935	61	35	to	to	ADP
dpc-3935	61	36	march	march	PROPN
dpc-3935	61	37	2022	2022	NUM
dpc-3935	61	38	were	be	AUX
dpc-3935	61	39	retrospectively	retrospectively	ADV
dpc-3935	61	40	reviewed	review	VERB
dpc-3935	61	41	.	.	PUNCT
dpc-3935	62	1	to	to	PART
dpc-3935	62	2	select	select	VERB
dpc-3935	62	3	patients	patient	NOUN
dpc-3935	62	4	to	to	PART
dpc-3935	62	5	address	address	VERB
dpc-3935	62	6	to	to	ADP
dpc-3935	62	7	genetic	genetic	ADJ
dpc-3935	62	8	counseling	counseling	NOUN
dpc-3935	62	9	,	,	PUNCT
dpc-3935	62	10	we	we	PRON
dpc-3935	62	11	employed	employ	VERB
dpc-3935	62	12	criteria	criterion	NOUN
dpc-3935	62	13	that	that	PRON
dpc-3935	62	14	mirror	mirror	VERB
dpc-3935	62	15	those	those	PRON
dpc-3935	62	16	used	use	VERB
dpc-3935	62	17	in	in	ADP
dpc-3935	62	18	countries	country	NOUN
dpc-3935	62	19	with	with	ADP
dpc-3935	62	20	a	a	DET
dpc-3935	62	21	high	high	ADJ
dpc-3935	62	22	incidence	incidence	NOUN
dpc-3935	62	23	of	of	ADP
dpc-3935	62	24	melanoma	melanoma	NOUN
dpc-3935	62	25	,	,	PUNCT
dpc-3935	62	26	such	such	ADJ
dpc-3935	62	27	as	as	ADP
dpc-3935	62	28	sweden	sweden	PROPN
dpc-3935	62	29	[	[	X
dpc-3935	62	30	21	21	NUM
dpc-3935	62	31	]	]	PUNCT
dpc-3935	62	32	paying	pay	VERB
dpc-3935	62	33	attention	attention	NOUN
dpc-3935	62	34	to	to	ADP
dpc-3935	62	35	the	the	DET
dpc-3935	62	36	number	number	NOUN
dpc-3935	62	37	of	of	ADP
dpc-3935	62	38	melanoma	melanoma	NOUN
dpc-3935	62	39	in	in	ADP
dpc-3935	62	40	case	case	NOUN
dpc-3935	62	41	of	of	ADP
dpc-3935	62	42	patients	patient	NOUN
dpc-3935	62	43	with	with	ADP
dpc-3935	62	44	multiple	multiple	ADJ
dpc-3935	62	45	or	or	CCONJ
dpc-3935	62	46	patients	patient	NOUN
dpc-3935	62	47	with	with	ADP
dpc-3935	62	48	a	a	DET
dpc-3935	62	49	positive	positive	ADJ
dpc-3935	62	50	family	family	NOUN
dpc-3935	62	51	history	history	NOUN
dpc-3935	62	52	of	of	ADP
dpc-3935	62	53	melanoma	melanoma	NOUN
dpc-3935	62	54	,	,	PUNCT
dpc-3935	62	55	to	to	ADP
dpc-3935	62	56	the	the	DET
dpc-3935	62	57	age	age	NOUN
dpc-3935	62	58	at	at	ADP
dpc-3935	62	59	diagnosis	diagnosis	NOUN
dpc-3935	62	60	and	and	CCONJ
dpc-3935	62	61	to	to	ADP
dpc-3935	62	62	family	family	NOUN
dpc-3935	62	63	history	history	NOUN
dpc-3935	62	64	of	of	ADP
dpc-3935	62	65	pc	pc	NOUN
dpc-3935	62	66	.	.	PUNCT
dpc-3935	63	1	patients	patient	NOUN
dpc-3935	63	2	with	with	ADP
dpc-3935	63	3	one	one	NUM
dpc-3935	63	4	or	or	CCONJ
dpc-3935	63	5	more	more	ADJ
dpc-3935	63	6	of	of	ADP
dpc-3935	63	7	the	the	DET
dpc-3935	63	8	following	follow	VERB
dpc-3935	63	9	criteria	criterion	NOUN
dpc-3935	63	10	were	be	AUX
dpc-3935	63	11	identified	identify	VERB
dpc-3935	63	12	:	:	PUNCT
dpc-3935	63	13	•	•	NUM
dpc-3935	63	14	multiple	multiple	ADJ
dpc-3935	63	15	melanomas	melanomas	NOUN
dpc-3935	63	16	(	(	PUNCT
dpc-3935	63	17	≥	≥	NOUN
dpc-3935	63	18	3	3	NUM
dpc-3935	63	19	)	)	PUNCT
dpc-3935	63	20	•	•	NOUN
dpc-3935	63	21	personal	personal	ADJ
dpc-3935	63	22	/	/	SYM
dpc-3935	63	23	family	family	NOUN
dpc-3935	63	24	history	history	NOUN
dpc-3935	63	25	for	for	ADP
dpc-3935	63	26	pc	pc	NOUN
dpc-3935	63	27	(	(	PUNCT
dpc-3935	63	28	up	up	ADP
dpc-3935	63	29	to	to	ADP
dpc-3935	63	30	the	the	DET
dpc-3935	63	31	second	second	ADJ
dpc-3935	63	32	degree	degree	NOUN
dpc-3935	63	33	of	of	ADP
dpc-3935	63	34	kinship	kinship	NOUN
dpc-3935	63	35	)	)	PUNCT
dpc-3935	63	36	•	•	NUM
dpc-3935	63	37	≥	≥	NOUN
dpc-3935	63	38	2	2	NUM
dpc-3935	63	39	melanomas	melanomas	NOUN
dpc-3935	63	40	among	among	ADP
dpc-3935	63	41	first	first	ADJ
dpc-3935	63	42	-	-	PUNCT
dpc-3935	63	43	degree	degree	NOUN
dpc-3935	63	44	relatives	relative	NOUN
dpc-3935	63	45	•	•	CCONJ
dpc-3935	63	46	first	first	ADJ
dpc-3935	63	47	-	-	PUNCT
dpc-3935	63	48	degree	degree	NOUN
dpc-3935	63	49	relatives	relative	NOUN
dpc-3935	63	50	with	with	ADP
dpc-3935	63	51	early	early	ADJ
dpc-3935	63	52	-	-	PUNCT
dpc-3935	63	53	onset	onset	NOUN
dpc-3935	63	54	melanoma	melanoma	NOUN
dpc-3935	63	55	(	(	PUNCT
dpc-3935	63	56	<	<	X
dpc-3935	63	57	45	45	NUM
dpc-3935	63	58	years	year	NOUN
dpc-3935	63	59	)	)	PUNCT
dpc-3935	63	60	forty	forty	NUM
dpc-3935	63	61	-	-	PUNCT
dpc-3935	63	62	six	six	NUM
dpc-3935	63	63	patients	patient	NOUN
dpc-3935	63	64	(	(	PUNCT
dpc-3935	63	65	3.5	3.5	NUM
dpc-3935	63	66	%	%	NOUN
dpc-3935	63	67	)	)	PUNCT
dpc-3935	63	68	met	meet	VERB
dpc-3935	63	69	the	the	DET
dpc-3935	63	70	selection	selection	NOUN
dpc-3935	63	71	criteria	criterion	NOUN
dpc-3935	63	72	,	,	PUNCT
dpc-3935	63	73	and	and	CCONJ
dpc-3935	63	74	35	35	NUM
dpc-3935	63	75	(	(	PUNCT
dpc-3935	63	76	76.1	76.1	NUM
dpc-3935	63	77	%	%	NOUN
dpc-3935	63	78	)	)	PUNCT
dpc-3935	63	79	agreed	agree	VERB
dpc-3935	63	80	to	to	PART
dpc-3935	63	81	undergo	undergo	VERB
dpc-3935	63	82	genetic	genetic	ADJ
dpc-3935	63	83	counseling	counseling	NOUN
dpc-3935	63	84	and	and	CCONJ
dpc-3935	63	85	testing	testing	NOUN
dpc-3935	63	86	for	for	ADP
dpc-3935	63	87	the	the	DET
dpc-3935	63	88	main	main	ADJ
dpc-3935	63	89	melanoma	melanoma	NOUN
dpc-3935	63	90	predisposition	predisposition	NOUN
dpc-3935	63	91	genes	gene	NOUN
dpc-3935	63	92	and	and	CCONJ
dpc-3935	63	93	were	be	AUX
dpc-3935	63	94	included	include	VERB
dpc-3935	63	95	in	in	ADP
dpc-3935	63	96	this	this	DET
dpc-3935	63	97	study	study	NOUN
dpc-3935	63	98	.	.	PUNCT
dpc-3935	64	1	the	the	DET
dpc-3935	64	2	study	study	NOUN
dpc-3935	64	3	protocol	protocol	NOUN
dpc-3935	64	4	was	be	AUX
dpc-3935	64	5	approved	approve	VERB
dpc-3935	64	6	by	by	ADP
dpc-3935	64	7	the	the	DET
dpc-3935	64	8	local	local	ADJ
dpc-3935	64	9	institutional	institutional	ADJ
dpc-3935	64	10	review	review	NOUN
dpc-3935	64	11	board	board	NOUN
dpc-3935	64	12	“	"	PUNCT
dpc-3935	64	13	comitato	comitato	PROPN
dpc-3935	64	14	etico	etico	NOUN
dpc-3935	64	15	per	per	ADP
dpc-3935	64	16	la	la	X
dpc-3935	64	17	sperimentazione	sperimentazione	PROPN
dpc-3935	64	18	clinica	clinica	PROPN
dpc-3935	64	19	delle	delle	PROPN
dpc-3935	64	20	province	province	PROPN
dpc-3935	64	21	di	di	PROPN
dpc-3935	64	22	verona	verona	PROPN
dpc-3935	64	23	e	e	PROPN
dpc-3935	64	24	rovigo	rovigo	PROPN
dpc-3935	64	25	”	"	PUNCT
dpc-3935	64	26	on	on	ADP
dpc-3935	64	27	19th	19th	NOUN
dpc-3935	64	28	of	of	ADP
dpc-3935	64	29	april	april	PROPN
dpc-3935	64	30	2023	2023	NUM
dpc-3935	64	31	(	(	PUNCT
dpc-3935	64	32	prot	prot	NOUN
dpc-3935	64	33	.	.	PUNCT
dpc-3935	65	1	n.	n.	NOUN
dpc-3935	65	2	24955	24955	NUM
dpc-3935	65	3	,	,	PUNCT
dpc-3935	65	4	26th	26th	NOUN
dpc-3935	65	5	of	of	ADP
dpc-3935	65	6	april	april	PROPN
dpc-3935	65	7	2023	2023	NUM
dpc-3935	65	8	)	)	PUNCT
dpc-3935	66	1	and	and	CCONJ
dpc-3935	66	2	it	it	PRON
dpc-3935	66	3	was	be	AUX
dpc-3935	66	4	in	in	ADP
dpc-3935	66	5	agreement	agreement	NOUN
dpc-3935	66	6	with	with	ADP
dpc-3935	66	7	the	the	DET
dpc-3935	66	8	principles	principle	NOUN
dpc-3935	66	9	of	of	ADP
dpc-3935	66	10	the	the	DET
dpc-3935	66	11	declaration	declaration	NOUN
dpc-3935	66	12	of	of	ADP
dpc-3935	66	13	helsinki	helsinki	PROPN
dpc-3935	66	14	.	.	PUNCT
dpc-3935	67	1	all	all	DET
dpc-3935	67	2	patients	patient	NOUN
dpc-3935	67	3	provided	provide	VERB
dpc-3935	67	4	a	a	DET
dpc-3935	67	5	signed	sign	VERB
dpc-3935	67	6	informed	informed	ADJ
dpc-3935	67	7	consent	consent	NOUN
dpc-3935	67	8	approved	approve	VERB
dpc-3935	67	9	by	by	ADP
dpc-3935	67	10	a	a	DET
dpc-3935	67	11	local	local	ADJ
dpc-3935	67	12	institutional	institutional	ADJ
dpc-3935	67	13	review	review	NOUN
dpc-3935	67	14	board	board	NOUN
dpc-3935	67	15	.	.	PUNCT
dpc-3935	68	1	for	for	ADP
dpc-3935	68	2	each	each	DET
dpc-3935	68	3	patient	patient	NOUN
dpc-3935	68	4	,	,	PUNCT
dpc-3935	68	5	the	the	DET
dpc-3935	68	6	diagnosis	diagnosis	NOUN
dpc-3935	68	7	of	of	ADP
dpc-3935	68	8	melanoma	melanoma	NOUN
dpc-3935	68	9	was	be	AUX
dpc-3935	68	10	confirmed	confirm	VERB
dpc-3935	68	11	by	by	ADP
dpc-3935	68	12	histopathological	histopathological	ADJ
dpc-3935	68	13	analysis	analysis	NOUN
dpc-3935	68	14	.	.	PUNCT
dpc-3935	69	1	data	datum	NOUN
dpc-3935	69	2	collected	collect	VERB
dpc-3935	69	3	the	the	DET
dpc-3935	69	4	following	follow	VERB
dpc-3935	69	5	patient	patient	ADJ
dpc-3935	69	6	data	datum	NOUN
dpc-3935	69	7	were	be	AUX
dpc-3935	69	8	collected	collect	VERB
dpc-3935	69	9	:	:	PUNCT
dpc-3935	69	10	environmental	environmental	ADJ
dpc-3935	69	11	risk	risk	NOUN
dpc-3935	69	12	factors	factor	NOUN
dpc-3935	69	13	(	(	PUNCT
dpc-3935	69	14	eg	eg	PROPN
dpc-3935	69	15	sun	sun	NOUN
dpc-3935	69	16	exposure	exposure	NOUN
dpc-3935	69	17	,	,	PUNCT
dpc-3935	69	18	history	history	NOUN
dpc-3935	69	19	of	of	ADP
dpc-3935	69	20	burns	burn	NOUN
dpc-3935	69	21	)	)	PUNCT
dpc-3935	69	22	,	,	PUNCT
dpc-3935	69	23	personal	personal	ADJ
dpc-3935	69	24	history	history	NOUN
dpc-3935	69	25	of	of	ADP
dpc-3935	69	26	cancer	cancer	NOUN
dpc-3935	69	27	(	(	PUNCT
dpc-3935	69	28	any	any	PRON
dpc-3935	69	29	)	)	PUNCT
dpc-3935	69	30	,	,	PUNCT
dpc-3935	69	31	family	family	NOUN
dpc-3935	69	32	history	history	NOUN
dpc-3935	69	33	of	of	ADP
dpc-3935	69	34	cancer	cancer	NOUN
dpc-3935	69	35	(	(	PUNCT
dpc-3935	69	36	any	any	PRON
dpc-3935	69	37	)	)	PUNCT
dpc-3935	69	38	,	,	PUNCT
dpc-3935	69	39	including	include	VERB
dpc-3935	69	40	the	the	DET
dpc-3935	69	41	elaboration	elaboration	NOUN
dpc-3935	69	42	of	of	ADP
dpc-3935	69	43	a	a	DET
dpc-3935	69	44	three	three	NUM
dpc-3935	69	45	-	-	PUNCT
dpc-3935	69	46	generations	generation	NOUN
dpc-3935	69	47	family	family	NOUN
dpc-3935	69	48	tree	tree	NOUN
dpc-3935	69	49	.	.	PUNCT
dpc-3935	70	1	genetic	genetic	ADJ
dpc-3935	70	2	counseling	counseling	NOUN
dpc-3935	70	3	and	and	CCONJ
dpc-3935	70	4	testing	testing	NOUN
dpc-3935	70	5	were	be	AUX
dpc-3935	70	6	centralized	centralize	VERB
dpc-3935	70	7	(	(	PUNCT
dpc-3935	70	8	medical	medical	ADJ
dpc-3935	70	9	genetics	genetic	NOUN
dpc-3935	70	10	unit	unit	NOUN
dpc-3935	70	11	,	,	PUNCT
dpc-3935	70	12	irccs	irccs	PROPN
dpc-3935	70	13	sacro	sacro	PROPN
dpc-3935	70	14	cuore	cuore	PROPN
dpc-3935	70	15	don	don	PROPN
dpc-3935	70	16	calabria	calabria	PROPN
dpc-3935	70	17	hospital	hospital	PROPN
dpc-3935	70	18	in	in	ADP
dpc-3935	70	19	negrar	negrar	PROPN
dpc-3935	70	20	di	di	PROPN
dpc-3935	70	21	valpolicella	valpolicella	PROPN
dpc-3935	70	22	,	,	PUNCT
dpc-3935	70	23	verona	verona	PROPN
dpc-3935	70	24	)	)	PUNCT
dpc-3935	70	25	for	for	ADP
dpc-3935	70	26	29	29	NUM
dpc-3935	70	27	patients	patient	NOUN
dpc-3935	70	28	(	(	PUNCT
dpc-3935	70	29	82.9	82.9	NUM
dpc-3935	70	30	%	%	NOUN
dpc-3935	70	31	)	)	PUNCT
dpc-3935	70	32	.	.	PUNCT
dpc-3935	71	1	six	six	NUM
dpc-3935	71	2	patients	patient	NOUN
dpc-3935	71	3	(	(	PUNCT
dpc-3935	71	4	17.1	17.1	NUM
dpc-3935	71	5	%	%	NOUN
dpc-3935	71	6	)	)	PUNCT
dpc-3935	71	7	were	be	AUX
dpc-3935	71	8	referred	refer	VERB
dpc-3935	71	9	to	to	ADP
dpc-3935	71	10	other	other	ADJ
dpc-3935	71	11	oncogenetic	oncogenetic	ADJ
dpc-3935	71	12	centers	center	NOUN
dpc-3935	71	13	for	for	ADP
dpc-3935	71	14	geographical	geographical	ADJ
dpc-3935	71	15	reasons	reason	NOUN
dpc-3935	71	16	.	.	PUNCT
dpc-3935	72	1	genetic	genetic	ADJ
dpc-3935	72	2	analysis	analysis	NOUN
dpc-3935	72	3	genetic	genetic	ADJ
dpc-3935	72	4	testing	testing	NOUN
dpc-3935	72	5	was	be	AUX
dpc-3935	72	6	performed	perform	VERB
dpc-3935	72	7	on	on	ADP
dpc-3935	72	8	dna	dna	PROPN
dpc-3935	72	9	extracted	extract	VERB
dpc-3935	72	10	from	from	ADP
dpc-3935	72	11	the	the	DET
dpc-3935	72	12	patient	patient	ADJ
dpc-3935	72	13	peripheral	peripheral	ADJ
dpc-3935	72	14	blood	blood	NOUN
dpc-3935	72	15	.	.	PUNCT
dpc-3935	73	1	genetic	genetic	ADJ
dpc-3935	73	2	testing	testing	NOUN
dpc-3935	73	3	provided	provide	VERB
dpc-3935	73	4	in	in	ADP
dpc-3935	73	5	irccs	irccs	PROPN
dpc-3935	73	6	sacro	sacro	PROPN
dpc-3935	73	7	cuore	cuore	PROPN
dpc-3935	73	8	don	don	PROPN
dpc-3935	73	9	calabria	calabria	PROPN
dpc-3935	73	10	hospital	hospital	PROPN
dpc-3935	73	11	in	in	ADP
dpc-3935	73	12	negrar	negrar	PROPN
dpc-3935	73	13	di	di	PROPN
dpc-3935	73	14	valpolicella	valpolicella	PROPN
dpc-3935	73	15	,	,	PUNCT
dpc-3935	73	16	varona	varona	NOUN
dpc-3935	73	17	analyzed	analyze	VERB
dpc-3935	73	18	cdkn2a	cdkn2a	PROPN
dpc-3935	73	19	,	,	PUNCT
dpc-3935	73	20	cdk4	cdk4	NOUN
dpc-3935	73	21	,	,	PUNCT
dpc-3935	73	22	pot1	pot1	PROPN
dpc-3935	73	23	,	,	PUNCT
dpc-3935	73	24	bap1	bap1	PROPN
dpc-3935	73	25	,	,	PUNCT
dpc-3935	73	26	mitf	mitf	NOUN
dpc-3935	73	27	,	,	PUNCT
dpc-3935	73	28	atm	atm	ADJ
dpc-3935	73	29	,	,	PUNCT
dpc-3935	73	30	and	and	CCONJ
dpc-3935	73	31	tert	tert	NOUN
dpc-3935	73	32	.	.	PUNCT
dpc-3935	74	1	mutational	mutational	ADJ
dpc-3935	74	2	analysis	analysis	NOUN
dpc-3935	74	3	was	be	AUX
dpc-3935	74	4	performed	perform	VERB
dpc-3935	74	5	by	by	ADP
dpc-3935	74	6	using	use	VERB
dpc-3935	74	7	massive	massive	ADJ
dpc-3935	74	8	parallel	parallel	ADJ
dpc-3935	74	9	sequencing	sequencing	NOUN
dpc-3935	74	10	with	with	ADP
dpc-3935	74	11	thermo	thermo	NOUN
dpc-3935	74	12	fisher	fisher	PROPN
dpc-3935	74	13	scientific	scientific	PROPN
dpc-3935	74	14	s5	s5	PROPN
dpc-3935	74	15	prime	prime	ADJ
dpc-3935	74	16	platform	platform	NOUN
dpc-3935	74	17	,	,	PUNCT
dpc-3935	74	18	with	with	ADP
dpc-3935	74	19	multiplex	multiplex	NOUN
dpc-3935	74	20	amplification	amplification	NOUN
dpc-3935	74	21	of	of	ADP
dpc-3935	74	22	all	all	DET
dpc-3935	74	23	exons	exon	NOUN
dpc-3935	74	24	and	and	CCONJ
dpc-3935	74	25	exon	exon	NOUN
dpc-3935	74	26	-	-	PUNCT
dpc-3935	74	27	intron	intron	NOUN
dpc-3935	74	28	junctions	junction	NOUN
dpc-3935	74	29	up	up	ADP
dpc-3935	74	30	to	to	ADP
dpc-3935	74	31	20bp	20bp	NOUN
dpc-3935	74	32	by	by	ADP
dpc-3935	74	33	a	a	DET
dpc-3935	74	34	custom	custom	NOUN
dpc-3935	74	35	ampliseq	ampliseq	NOUN
dpc-3935	74	36	on	on	ADP
dpc-3935	74	37	-	-	PUNCT
dpc-3935	74	38	demand	demand	NOUN
dpc-3935	74	39	panel	panel	NOUN
dpc-3935	74	40	iad1965574_1000	iad1965574_1000	NOUN
dpc-3935	74	41	(	(	PUNCT
dpc-3935	74	42	thermo	thermo	NOUN
dpc-3935	74	43	fisher	fisher	PROPN
dpc-3935	74	44	scientific	scientific	PROPN
dpc-3935	74	45	)	)	PUNCT
dpc-3935	74	46	.	.	PUNCT
dpc-3935	75	1	the	the	DET
dpc-3935	75	2	reads	read	NOUN
dpc-3935	75	3	obtained	obtain	VERB
dpc-3935	75	4	were	be	AUX
dpc-3935	75	5	aligned	align	VERB
dpc-3935	75	6	on	on	ADP
dpc-3935	75	7	reference	reference	NOUN
dpc-3935	75	8	genome	genome	NOUN
dpc-3935	75	9	grch37	grch37	NOUN
dpc-3935	75	10	/	/	SYM
dpc-3935	76	1	hg19	hg19	PROPN
dpc-3935	76	2	.	.	PUNCT
dpc-3935	77	1	data	datum	NOUN
dpc-3935	77	2	analysis	analysis	NOUN
dpc-3935	77	3	and	and	CCONJ
dpc-3935	77	4	variants	variant	NOUN
dpc-3935	77	5	annotation	annotation	NOUN
dpc-3935	77	6	was	be	AUX
dpc-3935	77	7	performed	perform	VERB
dpc-3935	77	8	using	use	VERB
dpc-3935	77	9	two	two	NUM
dpc-3935	77	10	distinct	distinct	ADJ
dpc-3935	77	11	pipelines	pipeline	NOUN
dpc-3935	77	12	:	:	PUNCT
dpc-3935	77	13	1	1	X
dpc-3935	77	14	)	)	PUNCT
dpc-3935	77	15	ion	ion	NOUN
dpc-3935	77	16	torrent	torrent	NOUN
dpc-3935	77	17	suite	suite	PROPN
dpc-3935	77	18	v5.12	v5.12	PROPN
dpc-3935	77	19	,	,	PUNCT
dpc-3935	77	20	ionreporter	ionreport	ADJ
dpc-3935	77	21	v5.12	v5.12	PROPN
dpc-3935	77	22	(	(	PUNCT
dpc-3935	77	23	thermo	thermo	NOUN
dpc-3935	77	24	fisher	fisher	PROPN
dpc-3935	77	25	scientific	scientific	PROPN
dpc-3935	77	26	)	)	PUNCT
dpc-3935	77	27	;	;	PUNCT
dpc-3935	77	28	2	2	X
dpc-3935	77	29	)	)	PUNCT
dpc-3935	77	30	ensembl	ensembl	NOUN
dpc-3935	77	31	variant	variant	ADJ
dpc-3935	77	32	effect	effect	NOUN
dpc-3935	77	33	predictor	predictor	NOUN
dpc-3935	77	34	(	(	PUNCT
dpc-3935	77	35	embl	embl	NOUN
dpc-3935	77	36	-	-	PUNCT
dpc-3935	77	37	ebi	ebi	PROPN
dpc-3935	77	38	,	,	PUNCT
dpc-3935	77	39	wellcome	wellcome	PROPN
dpc-3935	77	40	sanger	sanger	PROPN
dpc-3935	77	41	institute	institute	PROPN
dpc-3935	77	42	)	)	PUNCT
dpc-3935	77	43	.	.	PUNCT
dpc-3935	78	1	visualization	visualization	NOUN
dpc-3935	78	2	of	of	ADP
dpc-3935	78	3	the	the	DET
dpc-3935	78	4	reads	read	NOUN
dpc-3935	78	5	performed	perform	VERB
dpc-3935	78	6	with	with	ADP
dpc-3935	78	7	igv	igv	NOUN
dpc-3935	78	8	2.8	2.8	NUM
dpc-3935	78	9	(	(	PUNCT
dpc-3935	78	10	broad	broad	ADJ
dpc-3935	78	11	institute	institute	NOUN
dpc-3935	78	12	)	)	PUNCT
dpc-3935	78	13	.	.	PUNCT
dpc-3935	79	1	search	search	NOUN
dpc-3935	79	2	for	for	ADP
dpc-3935	79	3	large	large	ADJ
dpc-3935	79	4	deletions	deletion	NOUN
dpc-3935	79	5	/	/	SYM
dpc-3935	79	6	insertions	insertion	NOUN
dpc-3935	79	7	(	(	PUNCT
dpc-3935	79	8	copy	copy	VERB
dpc-3935	79	9	number	number	NOUN
dpc-3935	79	10	variation	variation	NOUN
dpc-3935	79	11	,	,	PUNCT
dpc-3935	79	12	cvn	cvn	PROPN
dpc-3935	79	13	)	)	PUNCT
dpc-3935	79	14	of	of	ADP
dpc-3935	79	15	the	the	DET
dpc-3935	79	16	genes	gene	NOUN
dpc-3935	79	17	included	include	VERB
dpc-3935	79	18	in	in	ADP
dpc-3935	79	19	the	the	DET
dpc-3935	79	20	panel	panel	NOUN
dpc-3935	79	21	performed	perform	VERB
dpc-3935	79	22	by	by	ADP
dpc-3935	79	23	cnvs	cnvs	NOUN
dpc-3935	79	24	analysis	analysis	NOUN
dpc-3935	79	25	with	with	ADP
dpc-3935	79	26	ion	ion	NOUN
dpc-3935	79	27	reporter	reporter	NOUN
dpc-3935	79	28	v5.12	v5.12	PROPN
dpc-3935	79	29	(	(	PUNCT
dpc-3935	79	30	thermo	thermo	NOUN
dpc-3935	79	31	fisher	fisher	PROPN
dpc-3935	79	32	scientific	scientific	PROPN
dpc-3935	79	33	)	)	PUNCT
dpc-3935	79	34	.	.	PUNCT
dpc-3935	80	1	genetic	genetic	ADJ
dpc-3935	80	2	testing	testing	NOUN
dpc-3935	80	3	performed	perform	VERB
dpc-3935	80	4	in	in	ADP
dpc-3935	80	5	other	other	ADJ
dpc-3935	80	6	centers	center	NOUN
dpc-3935	80	7	investigated	investigate	VERB
dpc-3935	80	8	a	a	DET
dpc-3935	80	9	larger	large	ADJ
dpc-3935	80	10	amplicon	amplicon	NOUN
dpc-3935	80	11	-	-	PUNCT
dpc-3935	80	12	based	base	VERB
dpc-3935	80	13	gene	gene	NOUN
dpc-3935	80	14	panel	panel	NOUN
dpc-3935	80	15	sequenced	sequence	VERB
dpc-3935	80	16	using	use	VERB
dpc-3935	80	17	thermo	thermo	NOUN
dpc-3935	80	18	fisher	fisher	PROPN
dpc-3935	80	19	scientific	scientific	PROPN
dpc-3935	80	20	s5	s5	PROPN
dpc-3935	80	21	prime	prime	ADJ
dpc-3935	80	22	platform	platform	NOUN
dpc-3935	80	23	analogous	analogous	ADJ
dpc-3935	80	24	to	to	ADP
dpc-3935	80	25	the	the	DET
dpc-3935	80	26	one	one	NUM
dpc-3935	80	27	of	of	ADP
dpc-3935	80	28	our	our	PRON
dpc-3935	80	29	reference	reference	NOUN
dpc-3935	80	30	lab	lab	NOUN
dpc-3935	80	31	.	.	PUNCT
dpc-3935	81	1	the	the	DET
dpc-3935	81	2	presence	presence	NOUN
dpc-3935	81	3	of	of	ADP
dpc-3935	81	4	the	the	DET
dpc-3935	81	5	seven	seven	NUM
dpc-3935	81	6	genes	gene	NOUN
dpc-3935	81	7	analyzed	analyze	VERB
dpc-3935	81	8	at	at	ADP
dpc-3935	81	9	the	the	DET
dpc-3935	81	10	sacro	sacro	PROPN
dpc-3935	81	11	cuore	cuore	PROPN
dpc-3935	81	12	don	don	PROPN
dpc-3935	81	13	calabria	calabria	PROPN
dpc-3935	81	14	hospital	hospital	PROPN
dpc-3935	81	15	panel	panel	NOUN
dpc-3935	81	16	was	be	AUX
dpc-3935	81	17	considered	consider	VERB
dpc-3935	81	18	 	 	SPACE
dpc-3935	81	19	mandatory	mandatory	ADJ
dpc-3935	81	20	to	to	PART
dpc-3935	81	21	include	include	VERB
dpc-3935	81	22	the	the	DET
dpc-3935	81	23	cases	case	NOUN
dpc-3935	81	24	in	in	ADP
dpc-3935	81	25	the	the	DET
dpc-3935	81	26	study	study	NOUN
dpc-3935	81	27	cohort	cohort	NOUN
dpc-3935	81	28	.	.	PUNCT
dpc-3935	82	1	reference	reference	NOUN
dpc-3935	82	2	databases	database	NOUN
dpc-3935	82	3	employed	employ	VERB
dpc-3935	82	4	for	for	ADP
dpc-3935	82	5	clinical	clinical	ADJ
dpc-3935	82	6	interpretation	interpretation	NOUN
dpc-3935	82	7	of	of	ADP
dpc-3935	82	8	gene	gene	NOUN
dpc-3935	82	9	variants	variant	NOUN
dpc-3935	82	10	were	be	AUX
dpc-3935	82	11	:	:	PUNCT
dpc-3935	82	12	clinvar	clinvar	PROPN
dpc-3935	82	13	,	,	PUNCT
dpc-3935	82	14	lovd	lovd	NOUN
dpc-3935	82	15	database	database	NOUN
dpc-3935	82	16	(	(	PUNCT
dpc-3935	82	17	lovd	lovd	NOUN
dpc-3935	82	18	v.3.0	v.3.0	AUX
dpc-3935	82	19	build	build	VERB
dpc-3935	82	20	29	29	NUM
dpc-3935	82	21	lovd	lovd	NOUN
dpc-3935	82	22	software	software	NOUN
dpc-3935	83	1	©	©	PROPN
dpc-3935	83	2	2004	2004	NUM
dpc-3935	83	3	-	-	SYM
dpc-3935	83	4	2023	2023	NUM
dpc-3935	83	5	)	)	PUNCT
dpc-3935	83	6	,	,	PUNCT
dpc-3935	83	7	varsome	varsome	NOUN
dpc-3935	83	8	and	and	CCONJ
dpc-3935	83	9	franklin	franklin	PROPN
dpc-3935	83	10	by	by	ADP
dpc-3935	83	11	genoox	genoox	PROPN
dpc-3935	83	12	.	.	PUNCT
dpc-3935	84	1	statistical	statistical	ADJ
dpc-3935	84	2	analysis	analysis	NOUN
dpc-3935	84	3	median	median	NOUN
dpc-3935	84	4	and	and	CCONJ
dpc-3935	84	5	interquartile	interquartile	ADJ
dpc-3935	84	6	range	range	NOUN
dpc-3935	84	7	were	be	AUX
dpc-3935	84	8	used	use	VERB
dpc-3935	84	9	to	to	PART
dpc-3935	84	10	present	present	VERB
dpc-3935	84	11	descriptive	descriptive	ADJ
dpc-3935	84	12	statistics	statistic	NOUN
dpc-3935	84	13	.	.	PUNCT
dpc-3935	85	1	the	the	DET
dpc-3935	85	2	association	association	NOUN
dpc-3935	85	3	between	between	ADP
dpc-3935	85	4	the	the	DET
dpc-3935	85	5	presence	presence	NOUN
dpc-3935	85	6	of	of	ADP
dpc-3935	85	7	pv	pv	NOUN
dpc-3935	85	8	in	in	ADP
dpc-3935	85	9	melanoma	melanoma	NOUN
dpc-3935	85	10	predisposition	predisposition	NOUN
dpc-3935	85	11	genes	gene	NOUN
dpc-3935	85	12	and	and	CCONJ
dpc-3935	85	13	various	various	ADJ
dpc-3935	85	14	clinical	clinical	ADJ
dpc-3935	85	15	characteristics	characteristic	NOUN
dpc-3935	85	16	was	be	AUX
dpc-3935	85	17	assessed	assess	VERB
dpc-3935	85	18	using	use	VERB
dpc-3935	86	1	the	the	DET
dpc-3935	86	2	chi	chi	ADJ
dpc-3935	86	3	-	-	PUNCT
dpc-3935	86	4	square	square	ADJ
dpc-3935	86	5	or	or	CCONJ
dpc-3935	86	6	fisher	fisher	PROPN
dpc-3935	86	7	exact	exact	ADJ
dpc-3935	86	8	test	test	NOUN
dpc-3935	86	9	.	.	PUNCT
dpc-3935	87	1	the	the	DET
dpc-3935	87	2	study	study	NOUN
dpc-3935	87	3	utilized	utilize	VERB
dpc-3935	87	4	a	a	DET
dpc-3935	87	5	two	two	NUM
dpc-3935	87	6	-	-	PUNCT
dpc-3935	87	7	sided	side	VERB
dpc-3935	87	8	fisher	fisher	PROPN
dpc-3935	87	9	exact	exact	ADJ
dpc-3935	87	10	test	test	NOUN
dpc-3935	87	11	in	in	ADP
dpc-3935	87	12	the	the	DET
dpc-3935	87	13	spss	spss	PROPN
dpc-3935	87	14	software	software	NOUN
dpc-3935	87	15	to	to	PART
dpc-3935	87	16	determine	determine	VERB
dpc-3935	87	17	the	the	DET
dpc-3935	87	18	statistical	statistical	ADJ
dpc-3935	87	19	association	association	NOUN
dpc-3935	87	20	.	.	PUNCT
dpc-3935	88	1	statistical	statistical	ADJ
dpc-3935	88	2	significance	significance	NOUN
dpc-3935	88	3	was	be	AUX
dpc-3935	88	4	set	set	VERB
dpc-3935	88	5	at	at	ADP
dpc-3935	88	6	a	a	DET
dpc-3935	88	7	p	p	NOUN
dpc-3935	88	8	value	value	NOUN
dpc-3935	88	9	threshold	threshold	NOUN
dpc-3935	88	10	of	of	ADP
dpc-3935	88	11	less	less	ADJ
dpc-3935	88	12	than	than	ADP
dpc-3935	88	13	0.05	0.05	NUM
dpc-3935	88	14	.	.	PUNCT
dpc-3935	89	1	statistical	statistical	ADJ
dpc-3935	89	2	analyses	analysis	NOUN
dpc-3935	89	3	were	be	AUX
dpc-3935	89	4	performed	perform	VERB
dpc-3935	89	5	using	use	VERB
dpc-3935	89	6	spss	spss	PROPN
dpc-3935	89	7	software	software	PROPN
dpc-3935	89	8	ver	ver	NOUN
dpc-3935	89	9	.	.	PROPN
dpc-3935	90	1	25	25	NUM
dpc-3935	90	2	(	(	PUNCT
dpc-3935	90	3	ibm	ibm	PROPN
dpc-3935	90	4	)	)	PUNCT
dpc-3935	90	5	4	4	NUM
dpc-3935	90	6	original	original	ADJ
dpc-3935	90	7	article	article	NOUN
dpc-3935	90	8	|	|	ADV
dpc-3935	90	9	dermatol	dermatol	ADJ
dpc-3935	90	10	pract	pract	NOUN
dpc-3935	90	11	concept	concept	NOUN
dpc-3935	90	12	.	.	PUNCT
dpc-3935	91	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	91	2	had	have	VERB
dpc-3935	91	3	two	two	NUM
dpc-3935	91	4	melanomas	melanoma	NOUN
dpc-3935	91	5	,	,	PUNCT
dpc-3935	91	6	the	the	DET
dpc-3935	91	7	first	first	ADJ
dpc-3935	91	8	at	at	ADP
dpc-3935	91	9	51	51	NUM
dpc-3935	91	10	years	year	NOUN
dpc-3935	91	11	,	,	PUNCT
dpc-3935	91	12	with	with	ADP
dpc-3935	91	13	a	a	DET
dpc-3935	91	14	total	total	ADJ
dpc-3935	91	15	nevi	nevi	ADJ
dpc-3935	91	16	number	number	NOUN
dpc-3935	91	17	>	>	NOUN
dpc-3935	91	18	100	100	NUM
dpc-3935	91	19	.	.	PUNCT
dpc-3935	92	1	his	his	PRON
dpc-3935	92	2	father	father	NOUN
dpc-3935	92	3	developed	develop	VERB
dpc-3935	92	4	a	a	DET
dpc-3935	92	5	pc	pc	NOUN
dpc-3935	92	6	.	.	PUNCT
dpc-3935	93	1	genetic	genetic	ADJ
dpc-3935	93	2	testing	testing	NOUN
dpc-3935	93	3	was	be	AUX
dpc-3935	93	4	proposed	propose	VERB
dpc-3935	93	5	to	to	ADP
dpc-3935	93	6	his	his	PRON
dpc-3935	93	7	brother	brother	NOUN
dpc-3935	93	8	,	,	PUNCT
dpc-3935	93	9	sister	sister	NOUN
dpc-3935	93	10	,	,	PUNCT
dpc-3935	93	11	and	and	CCONJ
dpc-3935	93	12	two	two	NUM
dpc-3935	93	13	children	child	NOUN
dpc-3935	93	14	;	;	PUNCT
dpc-3935	93	15	however	however	ADV
dpc-3935	93	16	,	,	PUNCT
dpc-3935	93	17	to	to	ADP
dpc-3935	93	18	our	our	PRON
dpc-3935	93	19	knowledge	knowledge	NOUN
dpc-3935	93	20	,	,	PUNCT
dpc-3935	93	21	none	none	NOUN
dpc-3935	93	22	was	be	AUX
dpc-3935	93	23	ultimately	ultimately	ADV
dpc-3935	93	24	tested	test	VERB
dpc-3935	93	25	due	due	ADP
dpc-3935	93	26	to	to	ADP
dpc-3935	93	27	unwillingness	unwillingness	NOUN
dpc-3935	93	28	.	.	PUNCT
dpc-3935	94	1	patient	patient	ADJ
dpc-3935	94	2	#	#	SYM
dpc-3935	94	3	26	26	NUM
dpc-3935	94	4	tested	test	VERB
dpc-3935	94	5	positive	positive	ADJ
dpc-3935	94	6	for	for	ADP
dpc-3935	94	7	c.150	c.150	PRON
dpc-3935	94	8	+	+	ADJ
dpc-3935	94	9	5del	5del	PROPN
dpc-3935	94	10	cdkn2a	cdkn2a	ADJ
dpc-3935	94	11	variant	variant	NOUN
dpc-3935	94	12	(	(	PUNCT
dpc-3935	94	13	nm_000077.5	nm_000077.5	ADJ
dpc-3935	94	14	:	:	PUNCT
dpc-3935	94	15	c.150	c.150	X
dpc-3935	94	16	+	+	NOUN
dpc-3935	94	17	5del	5del	NUM
dpc-3935	94	18	)	)	PUNCT
dpc-3935	94	19	,	,	PUNCT
dpc-3935	94	20	currently	currently	ADV
dpc-3935	94	21	classified	classify	VERB
dpc-3935	94	22	as	as	ADP
dpc-3935	94	23	vus	vus	NOUN
dpc-3935	94	24	.	.	PUNCT
dpc-3935	95	1	this	this	DET
dpc-3935	95	2	patient	patient	NOUN
dpc-3935	95	3	,	,	PUNCT
dpc-3935	95	4	diagnosed	diagnose	VERB
dpc-3935	95	5	with	with	ADP
dpc-3935	95	6	melanoma	melanoma	NOUN
dpc-3935	95	7	at	at	ADP
dpc-3935	95	8	age	age	NOUN
dpc-3935	95	9	26	26	NUM
dpc-3935	95	10	,	,	PUNCT
dpc-3935	95	11	also	also	ADV
dpc-3935	95	12	had	have	VERB
dpc-3935	95	13	a	a	DET
dpc-3935	95	14	family	family	NOUN
dpc-3935	95	15	history	history	NOUN
dpc-3935	95	16	of	of	ADP
dpc-3935	95	17	melanoma	melanoma	NOUN
dpc-3935	95	18	since	since	SCONJ
dpc-3935	95	19	his	his	PRON
dpc-3935	95	20	father	father	NOUN
dpc-3935	95	21	presented	present	VERB
dpc-3935	95	22	two	two	NUM
dpc-3935	95	23	melanomas	melanoma	NOUN
dpc-3935	95	24	at	at	ADP
dpc-3935	95	25	32	32	NUM
dpc-3935	95	26	and	and	CCONJ
dpc-3935	95	27	49	49	NUM
dpc-3935	95	28	.	.	PUNCT
dpc-3935	96	1	therefore	therefore	ADV
dpc-3935	96	2	,	,	PUNCT
dpc-3935	96	3	a	a	DET
dpc-3935	96	4	genetic	genetic	ADJ
dpc-3935	96	5	analysis	analysis	NOUN
dpc-3935	96	6	was	be	AUX
dpc-3935	96	7	also	also	ADV
dpc-3935	96	8	performed	perform	VERB
dpc-3935	96	9	on	on	ADP
dpc-3935	96	10	the	the	DET
dpc-3935	96	11	patient	patient	NOUN
dpc-3935	96	12	’s	’s	PART
dpc-3935	96	13	father	father	NOUN
dpc-3935	96	14	,	,	PUNCT
dpc-3935	96	15	who	who	PRON
dpc-3935	96	16	was	be	AUX
dpc-3935	96	17	a	a	DET
dpc-3935	96	18	carrier	carrier	NOUN
dpc-3935	96	19	of	of	ADP
dpc-3935	96	20	the	the	DET
dpc-3935	96	21	same	same	ADJ
dpc-3935	96	22	variant	variant	NOUN
dpc-3935	96	23	,	,	PUNCT
dpc-3935	96	24	to	to	PART
dpc-3935	96	25	evaluate	evaluate	VERB
dpc-3935	96	26	the	the	DET
dpc-3935	96	27	segregation	segregation	NOUN
dpc-3935	96	28	of	of	ADP
dpc-3935	96	29	this	this	DET
dpc-3935	96	30	variant	variant	NOUN
dpc-3935	96	31	in	in	ADP
dpc-3935	96	32	the	the	DET
dpc-3935	96	33	family	family	NOUN
dpc-3935	96	34	.	.	PUNCT
dpc-3935	97	1	patient	patient	ADJ
dpc-3935	97	2	#	#	SYM
dpc-3935	97	3	24	24	NUM
dpc-3935	97	4	had	have	VERB
dpc-3935	97	5	the	the	DET
dpc-3935	97	6	c.272c	c.272c	PROPN
dpc-3935	97	7	>	>	PROPN
dpc-3935	97	8	t	t	PROPN
dpc-3935	97	9	(	(	PUNCT
dpc-3935	97	10	p.pro91leu	p.pro91leu	ADJ
dpc-3935	97	11	)	)	PUNCT
dpc-3935	97	12	variant	variant	NOUN
dpc-3935	97	13	in	in	ADP
dpc-3935	97	14	the	the	DET
dpc-3935	97	15	mitf	mitf	ADJ
dpc-3935	97	16	gene	gene	NOUN
dpc-3935	97	17	(	(	PUNCT
dpc-3935	97	18	nm_001354604.2	nm_001354604.2	NOUN
dpc-3935	97	19	:	:	PUNCT
dpc-3935	97	20	c.272c	c.272c	PROPN
dpc-3935	97	21	>	>	PROPN
dpc-3935	97	22	t	t	PROPN
dpc-3935	97	23	)	)	PUNCT
dpc-3935	97	24	which	which	PRON
dpc-3935	97	25	is	be	AUX
dpc-3935	97	26	absent	absent	ADJ
dpc-3935	97	27	in	in	ADP
dpc-3935	97	28	clinvar	clinvar	NOUN
dpc-3935	97	29	but	but	CCONJ
dpc-3935	97	30	reported	report	VERB
dpc-3935	97	31	in	in	ADP
dpc-3935	97	32	dbsnp	dbsnp	ADJ
dpc-3935	97	33	database	database	NOUN
dpc-3935	97	34	with	with	ADP
dpc-3935	97	35	the	the	DET
dpc-3935	97	36	entry	entry	NOUN
dpc-3935	97	37	rs199832302	rs199832302	NOUN
dpc-3935	97	38	.	.	PUNCT
dpc-3935	98	1	the	the	DET
dpc-3935	98	2	variant	variant	NOUN
dpc-3935	98	3	is	be	AUX
dpc-3935	98	4	absent	absent	ADJ
dpc-3935	98	5	in	in	ADP
dpc-3935	98	6	gnomad	gnomad	ADJ
dpc-3935	98	7	population	population	NOUN
dpc-3935	98	8	database	database	NOUN
dpc-3935	98	9	and	and	CCONJ
dpc-3935	98	10	is	be	AUX
dpc-3935	98	11	predicted	predict	VERB
dpc-3935	98	12	to	to	PART
dpc-3935	98	13	be	be	AUX
dpc-3935	98	14	neutral	neutral	ADJ
dpc-3935	98	15	for	for	ADP
dpc-3935	98	16	the	the	DET
dpc-3935	98	17	protein	protein	NOUN
dpc-3935	98	18	function	function	NOUN
dpc-3935	98	19	by	by	ADP
dpc-3935	98	20	in	in	ADP
dpc-3935	98	21	silico	silico	NOUN
dpc-3935	98	22	predictors	predictor	NOUN
dpc-3935	98	23	.	.	PUNCT
dpc-3935	99	1	it	it	PRON
dpc-3935	99	2	is	be	AUX
dpc-3935	99	3	important	important	ADJ
dpc-3935	99	4	to	to	PART
dpc-3935	99	5	highlight	highlight	VERB
dpc-3935	99	6	that	that	SCONJ
dpc-3935	99	7	this	this	DET
dpc-3935	99	8	variant	variant	NOUN
dpc-3935	99	9	is	be	AUX
dpc-3935	99	10	absent	absent	ADJ
dpc-3935	99	11	in	in	ADP
dpc-3935	99	12	the	the	DET
dpc-3935	99	13	transcript	transcript	NOUN
dpc-3935	99	14	nm_000248.4	nm_000248.4	VERB
dpc-3935	99	15	because	because	SCONJ
dpc-3935	99	16	of	of	ADP
dpc-3935	99	17	its	its	PRON
dpc-3935	99	18	upstream	upstream	ADJ
dpc-3935	99	19	position	position	NOUN
dpc-3935	99	20	from	from	ADP
dpc-3935	99	21	the	the	DET
dpc-3935	99	22	start	start	NOUN
dpc-3935	99	23	codon	codon	NOUN
dpc-3935	99	24	,	,	PUNCT
dpc-3935	99	25	and	and	CCONJ
dpc-3935	99	26	this	this	DET
dpc-3935	99	27	aspect	aspect	NOUN
dpc-3935	99	28	may	may	AUX
dpc-3935	99	29	limit	limit	VERB
dpc-3935	99	30	its	its	PRON
dpc-3935	99	31	clinical	clinical	ADJ
dpc-3935	99	32	interest	interest	NOUN
dpc-3935	99	33	in	in	ADP
dpc-3935	99	34	hereditary	hereditary	ADJ
dpc-3935	99	35	melanoma	melanoma	NOUN
dpc-3935	99	36	.	.	PUNCT
dpc-3935	100	1	however	however	ADV
dpc-3935	100	2	,	,	PUNCT
dpc-3935	100	3	this	this	DET
dpc-3935	100	4	patient	patient	NOUN
dpc-3935	100	5	had	have	VERB
dpc-3935	100	6	a	a	DET
dpc-3935	100	7	potentially	potentially	ADV
dpc-3935	100	8	suggestive	suggestive	ADJ
dpc-3935	100	9	family	family	NOUN
dpc-3935	100	10	history	history	NOUN
dpc-3935	100	11	in	in	ADP
dpc-3935	100	12	both	both	CCONJ
dpc-3935	100	13	parental	parental	ADJ
dpc-3935	100	14	branches	branch	NOUN
dpc-3935	100	15	:	:	PUNCT
dpc-3935	100	16	his	his	PRON
dpc-3935	100	17	father	father	NOUN
dpc-3935	100	18	was	be	AUX
dpc-3935	100	19	diagnosed	diagnose	VERB
dpc-3935	100	20	with	with	ADP
dpc-3935	100	21	clear	clear	ADJ
dpc-3935	100	22	cell	cell	NOUN
dpc-3935	100	23	kidney	kidney	NOUN
dpc-3935	100	24	cancer	cancer	NOUN
dpc-3935	100	25	aged	age	VERB
dpc-3935	100	26	39	39	NUM
dpc-3935	100	27	years	year	NOUN
dpc-3935	100	28	,	,	PUNCT
dpc-3935	100	29	and	and	CCONJ
dpc-3935	100	30	his	his	PRON
dpc-3935	100	31	mother	mother	NOUN
dpc-3935	100	32	had	have	VERB
dpc-3935	100	33	thyroid	thyroid	NOUN
dpc-3935	100	34	cancer	cancer	NOUN
dpc-3935	100	35	at	at	ADP
dpc-3935	100	36	50	50	NUM
dpc-3935	100	37	and	and	CCONJ
dpc-3935	100	38	melanoma	melanoma	NOUN
dpc-3935	100	39	at	at	ADP
dpc-3935	100	40	59	59	NUM
dpc-3935	100	41	.	.	PUNCT
dpc-3935	101	1	the	the	DET
dpc-3935	101	2	father	father	PROPN
dpc-3935	101	3	renal	renal	ADJ
dpc-3935	101	4	cancer	cancer	NOUN
dpc-3935	101	5	and	and	CCONJ
dpc-3935	101	6	the	the	DET
dpc-3935	101	7	mother	mother	NOUN
dpc-3935	101	8	melanoma	melanoma	NOUN
dpc-3935	101	9	were	be	AUX
dpc-3935	101	10	confirmed	confirm	VERB
dpc-3935	101	11	through	through	ADP
dpc-3935	101	12	medical	medical	ADJ
dpc-3935	101	13	records	record	NOUN
dpc-3935	101	14	.	.	PUNCT
dpc-3935	102	1	on	on	ADP
dpc-3935	102	2	the	the	DET
dpc-3935	102	3	paternal	paternal	ADJ
dpc-3935	102	4	side	side	NOUN
dpc-3935	102	5	,	,	PUNCT
dpc-3935	102	6	an	an	DET
dpc-3935	102	7	uncle	uncle	NOUN
dpc-3935	102	8	presented	present	VERB
dpc-3935	102	9	with	with	ADP
dpc-3935	102	10	melanoma	melanoma	NOUN
dpc-3935	102	11	aged	aged	ADJ
dpc-3935	102	12	55	55	NUM
dpc-3935	102	13	,	,	PUNCT
dpc-3935	102	14	and	and	CCONJ
dpc-3935	102	15	a	a	DET
dpc-3935	102	16	second	second	ADJ
dpc-3935	102	17	uncle	uncle	NOUN
dpc-3935	102	18	with	with	ADP
dpc-3935	102	19	renal	renal	ADJ
dpc-3935	102	20	cancer	cancer	NOUN
dpc-3935	102	21	aged	age	VERB
dpc-3935	102	22	54	54	NUM
dpc-3935	102	23	.	.	PUNCT
dpc-3935	103	1	we	we	PRON
dpc-3935	103	2	could	could	AUX
dpc-3935	103	3	see	see	VERB
dpc-3935	103	4	the	the	DET
dpc-3935	103	5	father	father	NOUN
dpc-3935	103	6	patient	patient	NOUN
dpc-3935	103	7	in	in	ADP
dpc-3935	103	8	genetic	genetic	ADJ
dpc-3935	103	9	consultation	consultation	NOUN
dpc-3935	103	10	,	,	PUNCT
dpc-3935	103	11	and	and	CCONJ
dpc-3935	103	12	he	he	PRON
dpc-3935	103	13	accepted	accept	VERB
dpc-3935	103	14	to	to	PART
dpc-3935	103	15	undergo	undergo	VERB
dpc-3935	103	16	a	a	DET
dpc-3935	103	17	genetic	genetic	ADJ
dpc-3935	103	18	analysis	analysis	NOUN
dpc-3935	103	19	that	that	PRON
dpc-3935	103	20	failed	fail	VERB
dpc-3935	103	21	to	to	PART
dpc-3935	103	22	identify	identify	VERB
dpc-3935	103	23	the	the	DET
dpc-3935	103	24	mitf	mitf	NOUN
dpc-3935	103	25	c.272c	c.272c	PROPN
dpc-3935	103	26	>	>	PROPN
dpc-3935	103	27	t	t	PROPN
dpc-3935	103	28	(	(	PUNCT
dpc-3935	103	29	p.pro91leu	p.pro91leu	ADJ
dpc-3935	103	30	)	)	PUNCT
dpc-3935	103	31	,	,	PUNCT
dpc-3935	103	32	which	which	PRON
dpc-3935	103	33	was	be	AUX
dpc-3935	103	34	,	,	PUNCT
dpc-3935	103	35	in	in	ADP
dpc-3935	103	36	turn	turn	NOUN
dpc-3935	103	37	,	,	PUNCT
dpc-3935	103	38	of	of	ADP
dpc-3935	103	39	maternal	maternal	ADJ
dpc-3935	103	40	origin	origin	NOUN
dpc-3935	103	41	.	.	PUNCT
dpc-3935	104	1	two	two	NUM
dpc-3935	104	2	vus	vus	NOUN
dpc-3935	104	3	were	be	AUX
dpc-3935	104	4	detected	detect	VERB
dpc-3935	104	5	in	in	ADP
dpc-3935	104	6	atm	atm	PROPN
dpc-3935	104	7	gene	gene	NOUN
dpc-3935	104	8	in	in	ADP
dpc-3935	104	9	two	two	NUM
dpc-3935	104	10	distinct	distinct	ADJ
dpc-3935	104	11	individuals	individual	NOUN
dpc-3935	104	12	.	.	PUNCT
dpc-3935	105	1	the	the	DET
dpc-3935	105	2	atm	atm	NOUN
dpc-3935	105	3	 	 	SPACE
dpc-3935	105	4	c.8734a	c.8734a	PROPN
dpc-3935	105	5	>	>	X
dpc-3935	105	6	g	g	PROPN
dpc-3935	105	7	(	(	PUNCT
dpc-3935	105	8	p.arg2912gly	p.arg2912gly	ADV
dpc-3935	105	9	)	)	PUNCT
dpc-3935	105	10	(	(	PUNCT
dpc-3935	105	11	nm_000051.4	nm_000051.4	NOUN
dpc-3935	105	12	:	:	PUNCT
dpc-3935	105	13	c.8734a	c.8734a	NOUN
dpc-3935	105	14	>	>	NOUN
dpc-3935	105	15	g	g	NOUN
dpc-3935	105	16	)	)	PUNCT
dpc-3935	105	17	variant	variant	NOUN
dpc-3935	105	18	found	find	VERB
dpc-3935	105	19	in	in	ADP
dpc-3935	105	20	patient	patient	NOUN
dpc-3935	105	21	#	#	SYM
dpc-3935	105	22	1	1	NUM
dpc-3935	105	23	is	be	AUX
dpc-3935	105	24	currently	currently	ADV
dpc-3935	105	25	classified	classify	VERB
dpc-3935	105	26	as	as	ADP
dpc-3935	105	27	a	a	DET
dpc-3935	105	28	vus	vus	NOUN
dpc-3935	105	29	based	base	VERB
dpc-3935	105	30	on	on	ADP
dpc-3935	105	31	its	its	PRON
dpc-3935	105	32	presence	presence	NOUN
dpc-3935	105	33	at	at	ADP
dpc-3935	105	34	low	low	ADJ
dpc-3935	105	35	frequency	frequency	NOUN
dpc-3935	105	36	in	in	ADP
dpc-3935	105	37	gnomad	gnomad	ADJ
dpc-3935	105	38	database	database	NOUN
dpc-3935	105	39	in	in	ADP
dpc-3935	105	40	non	non	ADJ
dpc-3935	105	41	-	-	ADJ
dpc-3935	105	42	finnish	finnish	ADJ
dpc-3935	105	43	european	european	ADJ
dpc-3935	105	44	population	population	NOUN
dpc-3935	105	45	(	(	PUNCT
dpc-3935	105	46	0.04	0.04	NUM
dpc-3935	105	47	%	%	NOUN
dpc-3935	105	48	)	)	PUNCT
dpc-3935	105	49	with	with	ADP
dpc-3935	105	50	an	an	DET
dpc-3935	105	51	homozygote	homozygote	NOUN
dpc-3935	105	52	carrier	carrier	NOUN
dpc-3935	105	53	,	,	PUNCT
dpc-3935	105	54	altered	alter	VERB
dpc-3935	105	55	protein	protein	NOUN
dpc-3935	105	56	function	function	NOUN
dpc-3935	105	57	predicted	predict	VERB
dpc-3935	105	58	by	by	ADP
dpc-3935	105	59	in	in	ADP
dpc-3935	105	60	silico	silico	NOUN
dpc-3935	105	61	tools	tool	NOUN
dpc-3935	105	62	and	and	CCONJ
dpc-3935	105	63	moderate	moderate	ADJ
dpc-3935	105	64	aminoacid	aminoacid	NOUN
dpc-3935	105	65	conservation	conservation	NOUN
dpc-3935	105	66	score	score	NOUN
dpc-3935	105	67	.	.	PUNCT
dpc-3935	106	1	the	the	DET
dpc-3935	106	2	variant	variant	NOUN
dpc-3935	106	3	has	have	AUX
dpc-3935	106	4	been	be	AUX
dpc-3935	106	5	previously	previously	ADV
dpc-3935	106	6	reported	report	VERB
dpc-3935	106	7	in	in	ADP
dpc-3935	106	8	clinvar	clinvar	PROPN
dpc-3935	106	9	database	database	NOUN
dpc-3935	106	10	as	as	ADP
dpc-3935	106	11	vus	vus	NOUN
dpc-3935	106	12	.	.	PUNCT
dpc-3935	107	1	the	the	DET
dpc-3935	107	2	atm	atm	ADJ
dpc-3935	107	3	c.3393g	c.3393g	PROPN
dpc-3935	107	4	>	>	X
dpc-3935	107	5	a	a	DET
dpc-3935	107	6	(	(	PUNCT
dpc-3935	107	7	p.met1131ile	p.met1131ile	NOUN
dpc-3935	107	8	)	)	PUNCT
dpc-3935	107	9	(	(	PUNCT
dpc-3935	107	10	nm_000051.4	nm_000051.4	NOUN
dpc-3935	107	11	:	:	PUNCT
dpc-3935	107	12	c.3393g	c.3393g	PROPN
dpc-3935	107	13	>	>	X
dpc-3935	107	14	a	a	DET
dpc-3935	107	15	)	)	PUNCT
dpc-3935	107	16	variant	variant	NOUN
dpc-3935	107	17	found	find	VERB
dpc-3935	107	18	in	in	ADP
dpc-3935	107	19	patient	patient	NOUN
dpc-3935	107	20	#	#	SYM
dpc-3935	107	21	5	5	NUM
dpc-3935	107	22	is	be	AUX
dpc-3935	107	23	a	a	DET
dpc-3935	107	24	missense	missense	NOUN
dpc-3935	107	25	variant	variant	NOUN
dpc-3935	107	26	classified	classify	VERB
dpc-3935	107	27	as	as	ADP
dpc-3935	107	28	vus	vus	NOUN
dpc-3935	107	29	based	base	VERB
dpc-3935	107	30	on	on	ADP
dpc-3935	107	31	the	the	DET
dpc-3935	107	32	following	following	NOUN
dpc-3935	107	33	:	:	PUNCT
dpc-3935	107	34	lack	lack	NOUN
dpc-3935	107	35	of	of	ADP
dpc-3935	107	36	effect	effect	NOUN
dpc-3935	107	37	on	on	ADP
dpc-3935	107	38	the	the	DET
dpc-3935	107	39	protein	protein	NOUN
dpc-3935	107	40	function	function	NOUN
dpc-3935	107	41	predicted	predict	VERB
dpc-3935	107	42	by	by	ADP
dpc-3935	107	43	in	in	ADP
dpc-3935	107	44	silico	silico	NOUN
dpc-3935	107	45	tools	tool	NOUN
dpc-3935	107	46	,	,	PUNCT
dpc-3935	107	47	presence	presence	NOUN
dpc-3935	107	48	of	of	ADP
dpc-3935	107	49	previous	previous	ADJ
dpc-3935	107	50	classifications	classification	NOUN
dpc-3935	107	51	on	on	ADP
dpc-3935	107	52	clinvar	clinvar	PROPN
dpc-3935	107	53	database	database	NOUN
dpc-3935	107	54	,	,	PUNCT
dpc-3935	107	55	and	and	CCONJ
dpc-3935	107	56	extremely	extremely	ADV
dpc-3935	107	57	low	low	ADJ
dpc-3935	107	58	variant	variant	ADJ
dpc-3935	107	59	frequency	frequency	NOUN
dpc-3935	107	60	in	in	ADP
dpc-3935	107	61	non	non	ADJ
dpc-3935	107	62	-	-	ADJ
dpc-3935	107	63	finnish	finnish	ADJ
dpc-3935	107	64	european	european	ADJ
dpc-3935	107	65	population	population	NOUN
dpc-3935	107	66	in	in	ADP
dpc-3935	107	67	gnomad	gnomad	PROPN
dpc-3935	107	68	database	database	NOUN
dpc-3935	107	69	(	(	PUNCT
dpc-3935	107	70	0.0004	0.0004	NUM
dpc-3935	107	71	%	%	NOUN
dpc-3935	107	72	)	)	PUNCT
dpc-3935	107	73	.	.	PUNCT
dpc-3935	108	1	no	no	DET
dpc-3935	108	2	segregation	segregation	NOUN
dpc-3935	108	3	analysis	analysis	NOUN
dpc-3935	108	4	was	be	AUX
dpc-3935	108	5	performed	perform	VERB
dpc-3935	108	6	in	in	ADP
dpc-3935	108	7	these	these	DET
dpc-3935	108	8	two	two	NUM
dpc-3935	108	9	families	family	NOUN
dpc-3935	108	10	.	.	PUNCT
dpc-3935	109	1	results	result	VERB
dpc-3935	109	2	genetic	genetic	ADJ
dpc-3935	109	3	testing	testing	NOUN
dpc-3935	109	4	results	result	VERB
dpc-3935	109	5	genetic	genetic	ADJ
dpc-3935	109	6	testing	testing	NOUN
dpc-3935	109	7	revealed	reveal	VERB
dpc-3935	109	8	the	the	DET
dpc-3935	109	9	presence	presence	NOUN
dpc-3935	109	10	of	of	ADP
dpc-3935	109	11	hereditary	hereditary	ADJ
dpc-3935	109	12	melanoma	melanoma	NOUN
dpc-3935	109	13	in	in	ADP
dpc-3935	109	14	4	4	NUM
dpc-3935	109	15	out	out	ADP
dpc-3935	109	16	of	of	ADP
dpc-3935	109	17	35	35	NUM
dpc-3935	109	18	index	index	NOUN
dpc-3935	109	19	cases	case	NOUN
dpc-3935	109	20	(	(	PUNCT
dpc-3935	109	21	11.4	11.4	NUM
dpc-3935	109	22	%	%	NOUN
dpc-3935	109	23	)	)	PUNCT
dpc-3935	109	24	.	.	PUNCT
dpc-3935	110	1	in	in	ADP
dpc-3935	110	2	particular	particular	ADJ
dpc-3935	110	3	,	,	PUNCT
dpc-3935	110	4	three	three	NUM
dpc-3935	110	5	cdkn2a	cdkn2a	PROPN
dpc-3935	110	6	(	(	PUNCT
dpc-3935	110	7	8.6	8.6	NUM
dpc-3935	110	8	%	%	NOUN
dpc-3935	110	9	)	)	PUNCT
dpc-3935	110	10	and	and	CCONJ
dpc-3935	110	11	one	one	NUM
dpc-3935	110	12	mitf	mitf	NOUN
dpc-3935	110	13	(	(	PUNCT
dpc-3935	110	14	2.9	2.9	NUM
dpc-3935	110	15	%	%	NOUN
dpc-3935	110	16	)	)	PUNCT
dpc-3935	110	17	pv	pv	INTJ
dpc-3935	110	18	were	be	AUX
dpc-3935	110	19	identified	identify	VERB
dpc-3935	110	20	in	in	ADP
dpc-3935	110	21	four	four	NUM
dpc-3935	110	22	distinct	distinct	ADJ
dpc-3935	110	23	patients	patient	NOUN
dpc-3935	110	24	.	.	PUNCT
dpc-3935	111	1	moreover	moreover	ADV
dpc-3935	111	2	,	,	PUNCT
dpc-3935	111	3	variants	variant	NOUN
dpc-3935	111	4	currently	currently	ADV
dpc-3935	111	5	classified	classify	VERB
dpc-3935	111	6	as	as	SCONJ
dpc-3935	111	7	vus	vus	NOUN
dpc-3935	111	8	were	be	AUX
dpc-3935	111	9	detected	detect	VERB
dpc-3935	111	10	in	in	ADP
dpc-3935	111	11	cdkn2a	cdkn2a	PROPN
dpc-3935	111	12	(	(	PUNCT
dpc-3935	111	13	n	n	NOUN
dpc-3935	111	14	=	=	SYM
dpc-3935	111	15	1	1	NUM
dpc-3935	111	16	)	)	PUNCT
dpc-3935	111	17	,	,	PUNCT
dpc-3935	111	18	mitf	mitf	NOUN
dpc-3935	111	19	(	(	PUNCT
dpc-3935	111	20	n	n	NOUN
dpc-3935	111	21	=	=	SYM
dpc-3935	111	22	1	1	NUM
dpc-3935	111	23	)	)	PUNCT
dpc-3935	111	24	,	,	PUNCT
dpc-3935	111	25	and	and	CCONJ
dpc-3935	111	26	atm	atm	NOUN
dpc-3935	111	27	(	(	PUNCT
dpc-3935	111	28	n	n	NOUN
dpc-3935	111	29	=	=	SYM
dpc-3935	111	30	2	2	NUM
dpc-3935	111	31	)	)	PUNCT
dpc-3935	111	32	genes	gene	NOUN
dpc-3935	111	33	in	in	ADP
dpc-3935	111	34	4	4	NUM
dpc-3935	111	35	distinct	distinct	ADJ
dpc-3935	111	36	patients	patient	NOUN
dpc-3935	111	37	.	.	PUNCT
dpc-3935	112	1	median	median	ADJ
dpc-3935	112	2	age	age	NOUN
dpc-3935	112	3	at	at	ADP
dpc-3935	112	4	diagnosis	diagnosis	NOUN
dpc-3935	112	5	of	of	ADP
dpc-3935	112	6	first	first	ADJ
dpc-3935	112	7	melanoma	melanoma	NOUN
dpc-3935	112	8	was	be	AUX
dpc-3935	112	9	48.3	48.3	NUM
dpc-3935	112	10	years	year	NOUN
dpc-3935	112	11	(	(	PUNCT
dpc-3935	112	12	range	range	NOUN
dpc-3935	112	13	23	23	NUM
dpc-3935	112	14	-	-	SYM
dpc-3935	112	15	85	85	NUM
dpc-3935	112	16	)	)	PUNCT
dpc-3935	112	17	in	in	ADP
dpc-3935	112	18	the	the	DET
dpc-3935	112	19	whole	whole	ADJ
dpc-3935	112	20	cohort	cohort	NOUN
dpc-3935	112	21	,	,	PUNCT
dpc-3935	112	22	51.1	51.1	NUM
dpc-3935	112	23	(	(	PUNCT
dpc-3935	112	24	range	range	NOUN
dpc-3935	112	25	25	25	NUM
dpc-3935	112	26	-	-	SYM
dpc-3935	112	27	75	75	NUM
dpc-3935	112	28	)	)	PUNCT
dpc-3935	112	29	in	in	ADP
dpc-3935	112	30	patients	patient	NOUN
dpc-3935	112	31	with	with	ADP
dpc-3935	112	32	multiple	multiple	ADJ
dpc-3935	112	33	melanomas	melanoma	NOUN
dpc-3935	112	34	,	,	PUNCT
dpc-3935	112	35	and	and	CCONJ
dpc-3935	112	36	32.3	32.3	NUM
dpc-3935	112	37	(	(	PUNCT
dpc-3935	112	38	range	range	NOUN
dpc-3935	112	39	25	25	NUM
dpc-3935	112	40	-	-	SYM
dpc-3935	112	41	44	44	NUM
dpc-3935	112	42	)	)	PUNCT
dpc-3935	112	43	in	in	ADP
dpc-3935	112	44	patients	patient	NOUN
dpc-3935	112	45	harboring	harbor	VERB
dpc-3935	112	46	cdkn2a	cdkn2a	PROPN
dpc-3935	112	47	pv	pv	INTJ
dpc-3935	112	48	,	,	PUNCT
dpc-3935	112	49	while	while	SCONJ
dpc-3935	112	50	the	the	DET
dpc-3935	112	51	carrier	carrier	NOUN
dpc-3935	112	52	of	of	ADP
dpc-3935	112	53	mitf	mitf	PROPN
dpc-3935	112	54	pv	pv	PROPN
dpc-3935	112	55	presented	present	VERB
dpc-3935	112	56	his	his	PRON
dpc-3935	112	57	first	first	ADJ
dpc-3935	112	58	melanoma	melanoma	NOUN
dpc-3935	112	59	at	at	ADP
dpc-3935	112	60	51	51	NUM
dpc-3935	112	61	.	.	PUNCT
dpc-3935	113	1	all	all	DET
dpc-3935	113	2	carriers	carrier	NOUN
dpc-3935	113	3	of	of	ADP
dpc-3935	113	4	cdkn2a	cdkn2a	PROPN
dpc-3935	113	5	or	or	CCONJ
dpc-3935	113	6	mitf	mitf	ADJ
dpc-3935	113	7	pv	pv	NOUN
dpc-3935	113	8	had	have	VERB
dpc-3935	113	9	a	a	DET
dpc-3935	113	10	high	high	ADJ
dpc-3935	113	11	nevus	nevus	ADJ
dpc-3935	113	12	count	count	NOUN
dpc-3935	113	13	(	(	PUNCT
dpc-3935	113	14	two	two	NUM
dpc-3935	113	15	had	have	AUX
dpc-3935	113	16	more	more	ADJ
dpc-3935	113	17	than	than	ADP
dpc-3935	113	18	100	100	NUM
dpc-3935	113	19	nevi	nevus	NOUN
dpc-3935	113	20	,	,	PUNCT
dpc-3935	113	21	the	the	DET
dpc-3935	113	22	others	other	NOUN
dpc-3935	113	23	between	between	ADP
dpc-3935	113	24	50	50	NUM
dpc-3935	113	25	and	and	CCONJ
dpc-3935	113	26	100	100	NUM
dpc-3935	113	27	)	)	PUNCT
dpc-3935	113	28	.	.	PUNCT
dpc-3935	114	1	among	among	ADP
dpc-3935	114	2	patients	patient	NOUN
dpc-3935	114	3	with	with	ADP
dpc-3935	114	4	≥	≥	NUM
dpc-3935	114	5	3	3	NUM
dpc-3935	114	6	melanomas	melanoma	NOUN
dpc-3935	114	7	,	,	PUNCT
dpc-3935	114	8	the	the	DET
dpc-3935	114	9	prevalence	prevalence	NOUN
dpc-3935	114	10	of	of	ADP
dpc-3935	114	11	cdkn2a	cdkn2a	PROPN
dpc-3935	114	12	pv	pv	PROPN
dpc-3935	114	13	was	be	AUX
dpc-3935	114	14	18.2	18.2	NUM
dpc-3935	114	15	%	%	NOUN
dpc-3935	114	16	,	,	PUNCT
dpc-3935	114	17	whereas	whereas	SCONJ
dpc-3935	114	18	it	it	PRON
dpc-3935	114	19	was	be	AUX
dpc-3935	114	20	4.2	4.2	NUM
dpc-3935	114	21	%	%	NOUN
dpc-3935	114	22	in	in	ADP
dpc-3935	114	23	patients	patient	NOUN
dpc-3935	114	24	with	with	ADP
dpc-3935	114	25	one	one	NUM
dpc-3935	114	26	or	or	CCONJ
dpc-3935	114	27	two	two	NUM
dpc-3935	114	28	melanomas	melanoma	NOUN
dpc-3935	114	29	.	.	PUNCT
dpc-3935	115	1	all	all	DET
dpc-3935	115	2	cdkn2a	cdkn2a	PROPN
dpc-3935	115	3	pv	pv	INTJ
dpc-3935	115	4	identified	identify	VERB
dpc-3935	115	5	were	be	AUX
dpc-3935	115	6	missense	missense	NOUN
dpc-3935	115	7	and	and	CCONJ
dpc-3935	115	8	affected	affect	VERB
dpc-3935	115	9	p16ink4a	p16ink4a	PROPN
dpc-3935	115	10	.	.	PUNCT
dpc-3935	116	1	clinical	clinical	ADJ
dpc-3935	116	2	phenotypes	phenotype	NOUN
dpc-3935	116	3	and	and	CCONJ
dpc-3935	116	4	genetic	genetic	ADJ
dpc-3935	116	5	test	test	NOUN
dpc-3935	116	6	results	result	NOUN
dpc-3935	116	7	of	of	ADP
dpc-3935	116	8	patients	patient	NOUN
dpc-3935	116	9	harboring	harbor	VERB
dpc-3935	116	10	a	a	DET
dpc-3935	116	11	pv	pv	NOUN
dpc-3935	116	12	or	or	CCONJ
dpc-3935	116	13	a	a	DET
dpc-3935	116	14	vus	vus	NOUN
dpc-3935	116	15	are	be	AUX
dpc-3935	116	16	presented	present	VERB
dpc-3935	116	17	in	in	ADP
dpc-3935	116	18	table	table	NOUN
dpc-3935	116	19	1	1	NUM
dpc-3935	116	20	.	.	PUNCT
dpc-3935	117	1	the	the	DET
dpc-3935	117	2	general	general	ADJ
dpc-3935	117	3	characteristics	characteristic	NOUN
dpc-3935	117	4	of	of	ADP
dpc-3935	117	5	the	the	DET
dpc-3935	117	6	whole	whole	ADJ
dpc-3935	117	7	cohort	cohort	NOUN
dpc-3935	117	8	are	be	AUX
dpc-3935	117	9	shown	show	VERB
dpc-3935	117	10	in	in	ADP
dpc-3935	117	11	table	table	NOUN
dpc-3935	117	12	s1	s1	NOUN
dpc-3935	117	13	.	.	PUNCT
dpc-3935	118	1	patient	patient	NOUN
dpc-3935	118	2	#	#	SYM
dpc-3935	118	3	7	7	NUM
dpc-3935	118	4	carried	carry	VERB
dpc-3935	118	5	the	the	DET
dpc-3935	118	6	cdkn2a	cdkn2a	PROPN
dpc-3935	118	7	pv	pv	INTJ
dpc-3935	118	8	c.142c	c.142c	NOUN
dpc-3935	118	9	>	>	X
dpc-3935	118	10	a	a	DET
dpc-3935	118	11	(	(	PUNCT
dpc-3935	118	12	p.pro48thr	p.pro48thr	NOUN
dpc-3935	118	13	)	)	PUNCT
dpc-3935	118	14	(	(	PUNCT
dpc-3935	118	15	nm_000077.5	nm_000077.5	NOUN
dpc-3935	118	16	:	:	PUNCT
dpc-3935	119	1	c.142c	c.142c	ADJ
dpc-3935	119	2	>	>	X
dpc-3935	119	3	a	a	PRON
dpc-3935	119	4	)	)	PUNCT
dpc-3935	119	5	.	.	PUNCT
dpc-3935	120	1	he	he	PRON
dpc-3935	120	2	was	be	AUX
dpc-3935	120	3	diagnosed	diagnose	VERB
dpc-3935	120	4	with	with	ADP
dpc-3935	120	5	five	five	NUM
dpc-3935	120	6	melanomas	melanoma	NOUN
dpc-3935	120	7	,	,	PUNCT
dpc-3935	120	8	the	the	DET
dpc-3935	120	9	first	first	ADJ
dpc-3935	120	10	at	at	ADP
dpc-3935	120	11	28	28	NUM
dpc-3935	120	12	,	,	PUNCT
dpc-3935	120	13	with	with	ADP
dpc-3935	120	14	a	a	DET
dpc-3935	120	15	total	total	ADJ
dpc-3935	120	16	nevi	nevi	ADJ
dpc-3935	120	17	number	number	NOUN
dpc-3935	120	18	>	>	NOUN
dpc-3935	120	19	100	100	NUM
dpc-3935	120	20	.	.	PUNCT
dpc-3935	121	1	he	he	PRON
dpc-3935	121	2	presented	present	VERB
dpc-3935	121	3	a	a	DET
dpc-3935	121	4	positive	positive	ADJ
dpc-3935	121	5	family	family	NOUN
dpc-3935	121	6	history	history	NOUN
dpc-3935	121	7	of	of	ADP
dpc-3935	121	8	pc	pc	NOUN
dpc-3935	121	9	(	(	PUNCT
dpc-3935	121	10	paternal	paternal	ADJ
dpc-3935	121	11	aunt	aunt	NOUN
dpc-3935	121	12	)	)	PUNCT
dpc-3935	121	13	and	and	CCONJ
dpc-3935	121	14	possibly	possibly	ADV
dpc-3935	121	15	melanoma	melanoma	VERB
dpc-3935	121	16	aggregation	aggregation	NOUN
dpc-3935	121	17	in	in	ADP
dpc-3935	121	18	the	the	DET
dpc-3935	121	19	paternal	paternal	ADJ
dpc-3935	121	20	lineage	lineage	NOUN
dpc-3935	121	21	(	(	PUNCT
dpc-3935	121	22	his	his	PRON
dpc-3935	121	23	father	father	NOUN
dpc-3935	121	24	developed	develop	VERB
dpc-3935	121	25	a	a	DET
dpc-3935	121	26	non	non	ADJ
dpc-3935	121	27	-	-	ADJ
dpc-3935	121	28	specified	specified	ADJ
dpc-3935	121	29	skin	skin	NOUN
dpc-3935	121	30	cancer	cancer	NOUN
dpc-3935	121	31	in	in	ADP
dpc-3935	121	32	old	old	ADJ
dpc-3935	121	33	age	age	NOUN
dpc-3935	121	34	)	)	PUNCT
dpc-3935	121	35	.	.	PUNCT
dpc-3935	122	1	patient	patient	ADJ
dpc-3935	122	2	#	#	SYM
dpc-3935	122	3	8	8	NUM
dpc-3935	122	4	and	and	CCONJ
dpc-3935	122	5	patient	patient	ADJ
dpc-3935	122	6	#	#	SYM
dpc-3935	122	7	35	35	NUM
dpc-3935	122	8	harbored	harbor	VERB
dpc-3935	122	9	the	the	DET
dpc-3935	122	10	well	well	ADV
dpc-3935	122	11	-	-	PUNCT
dpc-3935	122	12	known	know	VERB
dpc-3935	122	13	c.301g	c.301g	PROPN
dpc-3935	122	14	>	>	X
dpc-3935	122	15	t	t	PROPN
dpc-3935	122	16	(	(	PUNCT
dpc-3935	122	17	p.gly101trp	p.gly101trp	PROPN
dpc-3935	122	18	)	)	PUNCT
dpc-3935	122	19	cdkn2a	cdkn2a	PROPN
dpc-3935	122	20	pv	pv	INTJ
dpc-3935	122	21	(	(	PUNCT
dpc-3935	122	22	nm_000077.5	nm_000077.5	ADJ
dpc-3935	122	23	:	:	PUNCT
dpc-3935	122	24	c.301g	c.301g	PROPN
dpc-3935	122	25	>	>	X
dpc-3935	122	26	t	t	PROPN
dpc-3935	122	27	)	)	PUNCT
dpc-3935	122	28	,	,	PUNCT
dpc-3935	122	29	which	which	PRON
dpc-3935	122	30	is	be	AUX
dpc-3935	122	31	particularly	particularly	ADV
dpc-3935	122	32	frequent	frequent	ADJ
dpc-3935	122	33	in	in	ADP
dpc-3935	122	34	italy	italy	PROPN
dpc-3935	122	35	and	and	CCONJ
dpc-3935	122	36	france	france	PROPN
dpc-3935	122	37	due	due	ADP
dpc-3935	122	38	to	to	ADP
dpc-3935	122	39	a	a	DET
dpc-3935	122	40	founder	founder	NOUN
dpc-3935	122	41	effect	effect	NOUN
dpc-3935	122	42	[	[	X
dpc-3935	122	43	22	22	NUM
dpc-3935	122	44	]	]	PUNCT
dpc-3935	122	45	.	.	PUNCT
dpc-3935	123	1	patient	patient	ADJ
dpc-3935	123	2	#	#	SYM
dpc-3935	123	3	8	8	NUM
dpc-3935	123	4	developed	develop	VERB
dpc-3935	123	5	four	four	NUM
dpc-3935	123	6	melanomas	melanoma	NOUN
dpc-3935	123	7	,	,	PUNCT
dpc-3935	123	8	the	the	DET
dpc-3935	123	9	first	first	ADJ
dpc-3935	123	10	at	at	ADP
dpc-3935	123	11	age	age	NOUN
dpc-3935	123	12	28	28	NUM
dpc-3935	123	13	.	.	PUNCT
dpc-3935	124	1	he	he	PRON
dpc-3935	124	2	had	have	VERB
dpc-3935	124	3	a	a	DET
dpc-3935	124	4	total	total	ADJ
dpc-3935	124	5	nevi	nevi	ADJ
dpc-3935	124	6	number	number	NOUN
dpc-3935	124	7	>	>	NOUN
dpc-3935	124	8	50	50	NUM
dpc-3935	124	9	.	.	PUNCT
dpc-3935	125	1	family	family	NOUN
dpc-3935	125	2	history	history	NOUN
dpc-3935	125	3	included	include	VERB
dpc-3935	125	4	pc	pc	NOUN
dpc-3935	125	5	(	(	PUNCT
dpc-3935	125	6	paternal	paternal	ADJ
dpc-3935	125	7	uncle	uncle	NOUN
dpc-3935	125	8	)	)	PUNCT
dpc-3935	125	9	.	.	PUNCT
dpc-3935	126	1	he	he	PRON
dpc-3935	126	2	has	have	VERB
dpc-3935	126	3	a	a	DET
dpc-3935	126	4	sister	sister	NOUN
dpc-3935	126	5	and	and	CCONJ
dpc-3935	126	6	a	a	DET
dpc-3935	126	7	32	32	NUM
dpc-3935	126	8	-	-	PUNCT
dpc-3935	126	9	year	year	NOUN
dpc-3935	126	10	-	-	PUNCT
dpc-3935	126	11	old	old	ADJ
dpc-3935	126	12	daughter	daughter	NOUN
dpc-3935	126	13	,	,	PUNCT
dpc-3935	126	14	who	who	PRON
dpc-3935	126	15	refused	refuse	VERB
dpc-3935	126	16	to	to	PART
dpc-3935	126	17	perform	perform	VERB
dpc-3935	126	18	genetic	genetic	ADJ
dpc-3935	126	19	counseling	counseling	NOUN
dpc-3935	126	20	and	and	CCONJ
dpc-3935	126	21	testing	testing	NOUN
dpc-3935	126	22	.	.	PUNCT
dpc-3935	127	1	patient	patient	ADJ
dpc-3935	127	2	#	#	SYM
dpc-3935	127	3	7	7	NUM
dpc-3935	127	4	had	have	VERB
dpc-3935	127	5	four	four	NUM
dpc-3935	127	6	melanomas	melanoma	NOUN
dpc-3935	127	7	,	,	PUNCT
dpc-3935	127	8	the	the	DET
dpc-3935	127	9	first	first	ADJ
dpc-3935	127	10	at	at	ADP
dpc-3935	127	11	25	25	NUM
dpc-3935	127	12	years	year	NOUN
dpc-3935	127	13	,	,	PUNCT
dpc-3935	127	14	with	with	ADP
dpc-3935	127	15	a	a	DET
dpc-3935	127	16	total	total	ADJ
dpc-3935	127	17	nevi	nevi	ADJ
dpc-3935	127	18	number	number	NOUN
dpc-3935	127	19	>	>	X
dpc-3935	127	20	50	50	NUM
dpc-3935	127	21	.	.	PUNCT
dpc-3935	128	1	family	family	NOUN
dpc-3935	128	2	history	history	NOUN
dpc-3935	128	3	included	include	VERB
dpc-3935	128	4	multiple	multiple	ADJ
dpc-3935	128	5	melanomas	melanomas	NOUN
dpc-3935	128	6	(	(	PUNCT
dpc-3935	128	7	sister	sister	NOUN
dpc-3935	128	8	)	)	PUNCT
dpc-3935	128	9	and	and	CCONJ
dpc-3935	128	10	pc	pc	NOUN
dpc-3935	128	11	(	(	PUNCT
dpc-3935	128	12	maternal	maternal	ADJ
dpc-3935	128	13	grandfather	grandfather	NOUN
dpc-3935	128	14	)	)	PUNCT
dpc-3935	128	15	.	.	PUNCT
dpc-3935	129	1	genetic	genetic	ADJ
dpc-3935	129	2	counseling	counseling	NOUN
dpc-3935	129	3	was	be	AUX
dpc-3935	129	4	extended	extend	VERB
dpc-3935	129	5	to	to	ADP
dpc-3935	129	6	the	the	DET
dpc-3935	129	7	mother	mother	NOUN
dpc-3935	129	8	,	,	PUNCT
dpc-3935	129	9	sister	sister	NOUN
dpc-3935	129	10	,	,	PUNCT
dpc-3935	129	11	and	and	CCONJ
dpc-3935	129	12	daughter	daughter	NOUN
dpc-3935	129	13	,	,	PUNCT
dpc-3935	129	14	and	and	CCONJ
dpc-3935	129	15	at	at	ADP
dpc-3935	129	16	the	the	DET
dpc-3935	129	17	time	time	NOUN
dpc-3935	129	18	of	of	ADP
dpc-3935	129	19	this	this	DET
dpc-3935	129	20	manuscript	manuscript	NOUN
dpc-3935	129	21	,	,	PUNCT
dpc-3935	129	22	the	the	DET
dpc-3935	129	23	results	result	NOUN
dpc-3935	129	24	were	be	AUX
dpc-3935	129	25	not	not	PART
dpc-3935	129	26	available	available	ADJ
dpc-3935	129	27	.	.	PUNCT
dpc-3935	130	1	patient	patient	ADJ
dpc-3935	130	2	#	#	SYM
dpc-3935	130	3	35	35	NUM
dpc-3935	130	4	developed	develop	VERB
dpc-3935	130	5	two	two	NUM
dpc-3935	130	6	melanomas	melanoma	NOUN
dpc-3935	130	7	(	(	PUNCT
dpc-3935	130	8	at	at	ADP
dpc-3935	130	9	44	44	NUM
dpc-3935	130	10	and	and	CCONJ
dpc-3935	130	11	56	56	NUM
dpc-3935	130	12	years	year	NOUN
dpc-3935	130	13	,	,	PUNCT
dpc-3935	130	14	respectively	respectively	ADV
dpc-3935	130	15	)	)	PUNCT
dpc-3935	130	16	,	,	PUNCT
dpc-3935	130	17	his	his	PRON
dpc-3935	130	18	sister	sister	NOUN
dpc-3935	130	19	had	have	VERB
dpc-3935	130	20	at	at	ADV
dpc-3935	130	21	least	least	ADJ
dpc-3935	130	22	four	four	NUM
dpc-3935	130	23	melanomas	melanoma	NOUN
dpc-3935	130	24	,	,	PUNCT
dpc-3935	130	25	and	and	CCONJ
dpc-3935	130	26	a	a	DET
dpc-3935	130	27	paternal	paternal	ADJ
dpc-3935	130	28	uncle	uncle	NOUN
dpc-3935	130	29	had	have	VERB
dpc-3935	130	30	a	a	DET
dpc-3935	130	31	melanoma	melanoma	NOUN
dpc-3935	130	32	at	at	ADP
dpc-3935	130	33	around	around	ADP
dpc-3935	130	34	40	40	NUM
dpc-3935	130	35	years	year	NOUN
dpc-3935	130	36	.	.	PUNCT
dpc-3935	131	1	he	he	PRON
dpc-3935	131	2	had	have	VERB
dpc-3935	131	3	a	a	DET
dpc-3935	131	4	total	total	ADJ
dpc-3935	131	5	nevi	nevi	ADJ
dpc-3935	131	6	number	number	NOUN
dpc-3935	131	7	>	>	NOUN
dpc-3935	131	8	50	50	NUM
dpc-3935	131	9	.	.	PUNCT
dpc-3935	132	1	the	the	DET
dpc-3935	132	2	sister	sister	NOUN
dpc-3935	132	3	,	,	PUNCT
dpc-3935	132	4	the	the	DET
dpc-3935	132	5	only	only	ADJ
dpc-3935	132	6	sib	sib	NOUN
dpc-3935	132	7	of	of	ADP
dpc-3935	132	8	patient	patient	ADJ
dpc-3935	132	9	#	#	SYM
dpc-3935	132	10	35	35	NUM
dpc-3935	132	11	,	,	PUNCT
dpc-3935	132	12	underwent	underwent	ADJ
dpc-3935	132	13	genetic	genetic	ADJ
dpc-3935	132	14	testing	testing	NOUN
dpc-3935	132	15	and	and	CCONJ
dpc-3935	132	16	tested	test	VERB
dpc-3935	132	17	positive	positive	ADJ
dpc-3935	132	18	.	.	PUNCT
dpc-3935	133	1	two	two	NUM
dpc-3935	133	2	out	out	ADP
dpc-3935	133	3	of	of	ADP
dpc-3935	133	4	his	his	PRON
dpc-3935	133	5	four	four	NUM
dpc-3935	133	6	children	child	NOUN
dpc-3935	133	7	had	have	VERB
dpc-3935	133	8	genetic	genetic	ADJ
dpc-3935	133	9	counseling	counseling	NOUN
dpc-3935	133	10	and	and	CCONJ
dpc-3935	133	11	tested	test	VERB
dpc-3935	133	12	negative	negative	ADJ
dpc-3935	133	13	.	.	PUNCT
dpc-3935	134	1	patient	patient	ADJ
dpc-3935	134	2	#	#	SYM
dpc-3935	134	3	33	33	NUM
dpc-3935	134	4	was	be	AUX
dpc-3935	134	5	found	find	VERB
dpc-3935	134	6	to	to	PART
dpc-3935	134	7	carry	carry	VERB
dpc-3935	134	8	the	the	DET
dpc-3935	134	9	mift	mift	NOUN
dpc-3935	134	10	pv	pv	X
dpc-3935	134	11	c.952g	c.952g	PROPN
dpc-3935	134	12	>	>	X
dpc-3935	134	13	a	a	DET
dpc-3935	134	14	(	(	PUNCT
dpc-3935	134	15	p.glu318lys	p.glu318ly	NOUN
dpc-3935	134	16	)	)	PUNCT
dpc-3935	134	17	(	(	PUNCT
dpc-3935	134	18	nm_000248.4	nm_000248.4	X
dpc-3935	134	19	:	:	PUNCT
dpc-3935	134	20	c.952g	c.952g	ADJ
dpc-3935	134	21	>	>	ADJ
dpc-3935	134	22	a.	a.	NOUN
dpc-3935	134	23	this	this	DET
dpc-3935	134	24	patient	patient	ADJ
dpc-3935	134	25	original	original	ADJ
dpc-3935	134	26	article	article	NOUN
dpc-3935	134	27	|	|	ADV
dpc-3935	134	28	dermatol	dermatol	ADJ
dpc-3935	134	29	pract	pract	NOUN
dpc-3935	134	30	concept	concept	NOUN
dpc-3935	134	31	.	.	PUNCT
dpc-3935	135	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	135	2	5	5	NUM
dpc-3935	135	3	ta	ta	PART
dpc-3935	135	4	b	b	PROPN
dpc-3935	135	5	le	le	ADP
dpc-3935	135	6	1	1	NUM
dpc-3935	135	7	.	.	PUNCT
dpc-3935	136	1	c	c	PROPN
dpc-3935	136	2	lin	lin	PROPN
dpc-3935	136	3	ic	ic	PROPN
dpc-3935	136	4	al	al	PROPN
dpc-3935	136	5	c	c	PROPN
dpc-3935	137	1	ha	ha	INTJ
dpc-3935	137	2	ra	ra	INTJ
dpc-3935	138	1	ct	ct	INTJ
dpc-3935	138	2	er	er	INTJ
dpc-3935	138	3	is	be	AUX
dpc-3935	138	4	ti	ti	X
dpc-3935	138	5	cs	cs	PROPN
dpc-3935	138	6	a	a	PRON
dpc-3935	138	7	nd	nd	NOUN
dpc-3935	138	8	g	g	NOUN
dpc-3935	138	9	en	en	ADP
dpc-3935	138	10	et	et	NOUN
dpc-3935	139	1	ic	ic	PROPN
dpc-3935	139	2	t	t	PROPN
dpc-3935	139	3	es	es	X
dpc-3935	139	4	t	t	PROPN
dpc-3935	139	5	re	re	PROPN
dpc-3935	139	6	su	su	PROPN
dpc-3935	140	1	lt	lt	PROPN
dpc-3935	140	2	s	s	PROPN
dpc-3935	140	3	of	of	ADP
dpc-3935	140	4	p	p	NOUN
dpc-3935	140	5	at	at	ADP
dpc-3935	140	6	ie	ie	X
dpc-3935	140	7	nt	not	PART
dpc-3935	140	8	s	s	PART
dpc-3935	140	9	ha	ha	INTJ
dpc-3935	140	10	rb	rb	NOUN
dpc-3935	140	11	or	or	CCONJ
dpc-3935	140	12	in	in	ADP
dpc-3935	140	13	g	g	PROPN
dpc-3935	140	14	a	a	DET
dpc-3935	140	15	pa	pa	PROPN
dpc-3935	140	16	th	th	X
dpc-3935	140	17	og	og	PROPN
dpc-3935	140	18	en	en	PROPN
dpc-3935	140	19	ic	ic	PROPN
dpc-3935	140	20	v	v	PROPN
dpc-3935	140	21	ar	ar	PROPN
dpc-3935	140	22	ia	ia	PROPN
dpc-3935	140	23	nt	not	PART
dpc-3935	140	24	o	o	PROPN
dpc-3935	140	25	r	r	NOUN
dpc-3935	140	26	a	a	DET
dpc-3935	140	27	va	va	PROPN
dpc-3935	140	28	ri	ri	PROPN
dpc-3935	140	29	an	an	DET
dpc-3935	140	30	t	t	NOUN
dpc-3935	140	31	cl	cl	NOUN
dpc-3935	140	32	as	as	ADP
dpc-3935	140	33	si	si	X
dpc-3935	140	34	fie	fie	PROPN
dpc-3935	140	35	d	d	PROPN
dpc-3935	140	36	as	as	ADP
dpc-3935	140	37	v	v	NUM
dpc-3935	140	38	ar	ar	PROPN
dpc-3935	140	39	ia	ia	PROPN
dpc-3935	140	40	nt	not	PART
dpc-3935	140	41	o	o	PROPN
dpc-3935	141	1	f	f	PROPN
dpc-3935	141	2	un	un	PROPN
dpc-3935	142	1	kn	kn	PROPN
dpc-3935	142	2	ow	ow	INTJ
dpc-3935	142	3	n	n	CCONJ
dpc-3935	142	4	cl	cl	NOUN
dpc-3935	142	5	in	in	ADP
dpc-3935	142	6	ic	ic	PROPN
dpc-3935	142	7	al	al	PROPN
dpc-3935	142	8	 	 	SPACE
dpc-3935	142	9	s	s	VERB
dpc-3935	142	10	ig	ig	PROPN
dpc-3935	142	11	ni	ni	PROPN
dpc-3935	142	12	fic	fic	PROPN
dpc-3935	142	13	an	an	PROPN
dpc-3935	142	14	ce	ce	PROPN
dpc-3935	142	15	pa	pa	PROPN
dpc-3935	142	16	ti	ti	PROPN
dpc-3935	142	17	en	en	PROPN
dpc-3935	142	18	t	t	PROPN
dpc-3935	142	19	i	i	PROPN
dpc-3935	142	20	d	d	PROPN
dpc-3935	142	21	n	n	PROPN
dpc-3935	142	22	.	.	PUNCT
dpc-3935	143	1	o	o	X
dpc-3935	144	1	f	f	X
dpc-3935	144	2	m	m	PROPN
dpc-3935	144	3	el	el	PROPN
dpc-3935	145	1	an	an	DET
dpc-3935	145	2	o	o	X
dpc-3935	145	3	m	m	VERB
dpc-3935	145	4	a	a	PRON
dpc-3935	145	5	n	n	NOUN
dpc-3935	146	1	o	o	NOUN
dpc-3935	147	1	f	f	X
dpc-3935	148	1	m	m	PROPN
dpc-3935	148	2	el	el	PROPN
dpc-3935	148	3	an	an	DET
dpc-3935	148	4	o	o	NOUN
dpc-3935	148	5	m	m	VERB
dpc-3935	148	6	a	a	PRON
dpc-3935	148	7	in	in	ADP
dpc-3935	148	8	th	th	X
dpc-3935	148	9	e	e	X
dpc-3935	149	1	fa	fa	X
dpc-3935	149	2	m	m	VERB
dpc-3935	149	3	ily	ily	ADV
dpc-3935	149	4	a	a	DET
dpc-3935	149	5	a	a	DET
dpc-3935	149	6	g	g	NOUN
dpc-3935	149	7	e	e	NOUN
dpc-3935	149	8	at	at	ADP
dpc-3935	149	9	d	d	PROPN
dpc-3935	149	10	ia	ia	PROPN
dpc-3935	149	11	g	g	PROPN
dpc-3935	149	12	n	n	ADV
dpc-3935	149	13	o	o	NOUN
dpc-3935	149	14	si	si	X
dpc-3935	149	15	s	s	X
dpc-3935	149	16	o	o	X
dpc-3935	149	17	f	f	X
dpc-3935	149	18	th	th	X
dpc-3935	149	19	e	e	X
dpc-3935	149	20	fi	fi	NOUN
dpc-3935	149	21	rs	rs	PROPN
dpc-3935	149	22	t	t	PROPN
dpc-3935	149	23	m	m	PROPN
dpc-3935	149	24	el	el	PROPN
dpc-3935	150	1	an	an	DET
dpc-3935	150	2	o	o	X
dpc-3935	150	3	m	m	VERB
dpc-3935	150	4	a	a	DET
dpc-3935	150	5	fh	fh	INTJ
dpc-3935	150	6	o	o	X
dpc-3935	151	1	f	f	X
dpc-3935	151	2	pc	pc	VERB
dpc-3935	151	3	a	a	PRON
dpc-3935	151	4	to	to	ADP
dpc-3935	151	5	ta	ta	ADP
dpc-3935	151	6	l	l	NOUN
dpc-3935	151	7	n	n	ADJ
dpc-3935	151	8	ev	ev	ADP
dpc-3935	151	9	u	u	NOUN
dpc-3935	151	10	s	s	PART
dpc-3935	151	11	co	co	NOUN
dpc-3935	151	12	u	u	NOUN
dpc-3935	151	13	n	n	ADV
dpc-3935	151	14	tb	tb	X
dpc-3935	151	15	fi	fi	NOUN
dpc-3935	151	16	tz	tz	NOUN
dpc-3935	151	17	p	p	NOUN
dpc-3935	151	18	at	at	ADP
dpc-3935	151	19	ri	ri	PROPN
dpc-3935	151	20	ck	ck	INTJ
dpc-3935	151	21	sk	sk	INTJ
dpc-3935	151	22	in	in	ADP
dpc-3935	151	23	t	t	PROPN
dpc-3935	151	24	yp	yp	X
dpc-3935	152	1	e	e	PROPN
dpc-3935	152	2	g	g	PROPN
dpc-3935	152	3	en	en	X
dpc-3935	152	4	e	e	X
dpc-3935	152	5	g	g	PROPN
dpc-3935	152	6	en	en	ADP
dpc-3935	152	7	et	et	NOUN
dpc-3935	152	8	ic	ic	PROPN
dpc-3935	152	9	c	c	NOUN
dpc-3935	152	10	h	h	NOUN
dpc-3935	152	11	an	an	DET
dpc-3935	152	12	g	g	NOUN
dpc-3935	152	13	e	e	NOUN
dpc-3935	152	14	(	(	PUNCT
dpc-3935	152	15	h	h	NOUN
dpc-3935	152	16	g	g	PROPN
dpc-3935	152	17	v	v	NOUN
dpc-3935	152	18	s	s	PART
dpc-3935	152	19	n	n	PRON
dpc-3935	152	20	o	o	NOUN
dpc-3935	152	21	m	m	NOUN
dpc-3935	152	22	en	en	X
dpc-3935	152	23	cl	cl	NOUN
dpc-3935	152	24	at	at	ADP
dpc-3935	152	25	u	u	NOUN
dpc-3935	152	26	re	re	X
dpc-3935	152	27	)	)	PUNCT
dpc-3935	153	1	pr	pr	VERB
dpc-3935	153	2	o	o	X
dpc-3935	153	3	te	te	INTJ
dpc-3935	153	4	in	in	ADP
dpc-3935	153	5	c	c	PROPN
dpc-3935	153	6	h	h	NOUN
dpc-3935	153	7	an	an	DET
dpc-3935	153	8	g	g	PROPN
dpc-3935	153	9	e	e	PROPN
dpc-3935	153	10	v	v	PROPN
dpc-3935	153	11	ar	ar	PROPN
dpc-3935	153	12	ia	ia	PROPN
dpc-3935	153	13	n	n	PROPN
dpc-3935	153	14	t	t	PROPN
dpc-3935	153	15	in	in	ADP
dpc-3935	153	16	te	te	PROPN
dpc-3935	153	17	rp	rp	X
dpc-3935	153	18	re	re	VERB
dpc-3935	153	19	ta	ta	ADP
dpc-3935	153	20	ti	ti	X
dpc-3935	153	21	o	o	PROPN
dpc-3935	153	22	n	n	CCONJ
dpc-3935	153	23	#	#	SYM
dpc-3935	153	24	1	1	NUM
dpc-3935	153	25	3	3	NUM
dpc-3935	153	26	3	3	NUM
dpc-3935	153	27	64	64	NUM
dpc-3935	153	28	no	no	DET
dpc-3935	153	29	3	3	NUM
dpc-3935	153	30	3	3	NUM
dpc-3935	153	31	a	a	DET
dpc-3935	153	32	t	t	NOUN
dpc-3935	153	33	m	m	VERB
dpc-3935	153	34	n	n	PRON
dpc-3935	153	35	m	m	NOUN
dpc-3935	153	36	_	_	NOUN
dpc-3935	153	37	0	0	PUNCT
dpc-3935	153	38	00	00	NUM
dpc-3935	153	39	05	05	NUM
dpc-3935	153	40	1	1	NUM
dpc-3935	153	41	.	.	NOUN
dpc-3935	153	42	4	4	NUM
dpc-3935	153	43	:	:	PUNCT
dpc-3935	153	44	c.	c.	NOUN
dpc-3935	153	45	87	87	NUM
dpc-3935	153	46	34	34	NUM
dpc-3935	153	47	a	a	DET
dpc-3935	153	48	>	>	X
dpc-3935	153	49	g	g	PROPN
dpc-3935	153	50	p.	p.	NOUN
dpc-3935	154	1	a	a	DET
dpc-3935	154	2	rg	rg	PROPN
dpc-3935	154	3	29	29	NUM
dpc-3935	154	4	12	12	NUM
dpc-3935	154	5	g	g	NOUN
dpc-3935	154	6	ly	ly	ADP
dpc-3935	154	7	v	v	ADP
dpc-3935	154	8	u	u	NOUN
dpc-3935	154	9	s	s	PART
dpc-3935	154	10	#	#	SYM
dpc-3935	154	11	5	5	NUM
dpc-3935	154	12	3	3	NUM
dpc-3935	154	13	4	4	NUM
dpc-3935	154	14	54	54	NUM
dpc-3935	154	15	no	no	DET
dpc-3935	154	16	3	3	NUM
dpc-3935	154	17	3	3	NUM
dpc-3935	154	18	a	a	DET
dpc-3935	154	19	t	t	NOUN
dpc-3935	154	20	m	m	VERB
dpc-3935	154	21	n	n	PRON
dpc-3935	154	22	m	m	NOUN
dpc-3935	154	23	_	_	NOUN
dpc-3935	154	24	0	0	PUNCT
dpc-3935	154	25	00	00	NUM
dpc-3935	154	26	05	05	NUM
dpc-3935	154	27	1	1	NUM
dpc-3935	154	28	.	.	NOUN
dpc-3935	154	29	4	4	NUM
dpc-3935	154	30	:	:	PUNCT
dpc-3935	154	31	c.	c.	NOUN
dpc-3935	154	32	33	33	NUM
dpc-3935	154	33	93	93	NUM
dpc-3935	154	34	g	g	NOUN
dpc-3935	154	35	>	>	PUNCT
dpc-3935	154	36	a	a	DET
dpc-3935	154	37	p.	p.	NOUN
dpc-3935	154	38	m	m	VERB
dpc-3935	154	39	et	et	NOUN
dpc-3935	154	40	11	11	NUM
dpc-3935	154	41	31	31	NUM
dpc-3935	154	42	il	il	PROPN
dpc-3935	154	43	e	e	PROPN
dpc-3935	154	44	v	v	ADP
dpc-3935	154	45	u	u	PROPN
dpc-3935	154	46	s	s	PART
dpc-3935	154	47	#	#	SYM
dpc-3935	154	48	7	7	NUM
dpc-3935	154	49	5	5	NUM
dpc-3935	154	50	7	7	NUM
dpc-3935	154	51	28	28	NUM
dpc-3935	154	52	ye	ye	NOUN
dpc-3935	154	53	s	s	NOUN
dpc-3935	154	54	4	4	NUM
dpc-3935	154	55	3	3	NUM
dpc-3935	154	56	c	c	NOUN
dpc-3935	154	57	d	d	X
dpc-3935	154	58	k	k	PROPN
dpc-3935	154	59	n	n	PROPN
dpc-3935	154	60	2a	2a	NUM
dpc-3935	154	61	n	n	PRON
dpc-3935	154	62	m	m	NOUN
dpc-3935	154	63	_	_	NOUN
dpc-3935	154	64	0	0	PUNCT
dpc-3935	154	65	00	00	NUM
dpc-3935	154	66	07	07	NUM
dpc-3935	154	67	7	7	NUM
dpc-3935	154	68	.	.	NOUN
dpc-3935	154	69	5	5	NUM
dpc-3935	154	70	:	:	PUNCT
dpc-3935	154	71	c.	c.	NOUN
dpc-3935	154	72	14	14	NUM
dpc-3935	154	73	2c	2c	NUM
dpc-3935	154	74	>	>	PUNCT
dpc-3935	154	75	a	a	DET
dpc-3935	154	76	p.	p.	NOUN
dpc-3935	154	77	pr	pr	NOUN
dpc-3935	155	1	o4	o4	PROPN
dpc-3935	155	2	8	8	NUM
dpc-3935	155	3	t	t	NOUN
dpc-3935	155	4	hr	hr	NOUN
dpc-3935	155	5	pv	pv	NOUN
dpc-3935	155	6	#	#	SYM
dpc-3935	155	7	8	8	NUM
dpc-3935	155	8	4	4	NUM
dpc-3935	155	9	5	5	NUM
dpc-3935	155	10	25	25	NUM
dpc-3935	155	11	ye	ye	NOUN
dpc-3935	155	12	s	s	NOUN
dpc-3935	155	13	3	3	NUM
dpc-3935	155	14	3	3	NUM
dpc-3935	155	15	c	c	NOUN
dpc-3935	155	16	d	d	X
dpc-3935	155	17	k	k	PROPN
dpc-3935	155	18	n	n	PROPN
dpc-3935	155	19	2a	2a	NUM
dpc-3935	155	20	n	n	PRON
dpc-3935	155	21	m	m	NOUN
dpc-3935	155	22	_	_	NOUN
dpc-3935	155	23	0	0	PUNCT
dpc-3935	155	24	00	00	NUM
dpc-3935	155	25	07	07	NUM
dpc-3935	155	26	7	7	NUM
dpc-3935	155	27	.	.	NOUN
dpc-3935	155	28	5	5	NUM
dpc-3935	155	29	:	:	PUNCT
dpc-3935	155	30	c.	c.	NOUN
dpc-3935	155	31	30	30	NUM
dpc-3935	155	32	1	1	NUM
dpc-3935	155	33	g	g	NOUN
dpc-3935	155	34	>	>	X
dpc-3935	155	35	t	t	PROPN
dpc-3935	156	1	p.	p.	NOUN
dpc-3935	156	2	g	g	NOUN
dpc-3935	157	1	ly	ly	ADP
dpc-3935	157	2	10	10	NUM
dpc-3935	157	3	1	1	NUM
dpc-3935	157	4	t	t	NOUN
dpc-3935	157	5	rp	rp	NOUN
dpc-3935	157	6	pv	pv	NOUN
dpc-3935	157	7	#	#	SYM
dpc-3935	157	8	2	2	NUM
dpc-3935	157	9	4	4	NUM
dpc-3935	157	10	1	1	NUM
dpc-3935	157	11	2	2	NUM
dpc-3935	157	12	39	39	NUM
dpc-3935	157	13	no	no	DET
dpc-3935	157	14	3	3	NUM
dpc-3935	157	15	1	1	NUM
dpc-3935	157	16	m	m	NOUN
dpc-3935	157	17	it	it	PRON
dpc-3935	157	18	f	f	NOUN
dpc-3935	157	19	n	n	INTJ
dpc-3935	157	20	m	m	VERB
dpc-3935	157	21	_	_	NOUN
dpc-3935	157	22	0	0	NUM
dpc-3935	157	23	01	01	NUM
dpc-3935	157	24	35	35	NUM
dpc-3935	157	25	46	46	NUM
dpc-3935	157	26	04	04	NUM
dpc-3935	158	1	.2	.2	NUM
dpc-3935	158	2	:	:	PUNCT
dpc-3935	158	3	c	c	NOUN
dpc-3935	158	4	.2	.2	NUM
dpc-3935	158	5	72	72	NUM
dpc-3935	158	6	c	c	NOUN
dpc-3935	158	7	>	>	PROPN
dpc-3935	158	8	t	t	PROPN
dpc-3935	159	1	p.	p.	NOUN
dpc-3935	159	2	pr	pr	NOUN
dpc-3935	159	3	o9	o9	PROPN
dpc-3935	159	4	1l	1l	PROPN
dpc-3935	159	5	eu	eu	PROPN
dpc-3935	159	6	v	v	ADP
dpc-3935	159	7	u	u	PROPN
dpc-3935	159	8	s	s	PART
dpc-3935	159	9	#	#	SYM
dpc-3935	159	10	2	2	NUM
dpc-3935	159	11	6	6	NUM
dpc-3935	159	12	1	1	NUM
dpc-3935	159	13	3	3	NUM
dpc-3935	159	14	26	26	NUM
dpc-3935	159	15	no	no	DET
dpc-3935	159	16	2	2	NUM
dpc-3935	159	17	2	2	NUM
dpc-3935	159	18	c	c	NOUN
dpc-3935	159	19	d	d	X
dpc-3935	159	20	k	k	PROPN
dpc-3935	159	21	n	n	PROPN
dpc-3935	159	22	2a	2a	NUM
dpc-3935	159	23	n	n	PRON
dpc-3935	159	24	m	m	NOUN
dpc-3935	159	25	_	_	NOUN
dpc-3935	159	26	0	0	PUNCT
dpc-3935	159	27	00	00	NUM
dpc-3935	159	28	07	07	NUM
dpc-3935	159	29	7	7	NUM
dpc-3935	159	30	.	.	NOUN
dpc-3935	159	31	5	5	NUM
dpc-3935	159	32	:	:	PUNCT
dpc-3935	159	33	c.	c.	NOUN
dpc-3935	159	34	15	15	NUM
dpc-3935	159	35	0	0	NUM
dpc-3935	159	36	+	+	NUM
dpc-3935	160	1	5d	5d	NUM
dpc-3935	160	2	el	el	PROPN
dpc-3935	160	3	v	v	NUM
dpc-3935	160	4	u	u	PROPN
dpc-3935	160	5	s	s	PART
dpc-3935	160	6	#	#	SYM
dpc-3935	160	7	3	3	NUM
dpc-3935	160	8	3	3	NUM
dpc-3935	160	9	2	2	NUM
dpc-3935	160	10	2	2	NUM
dpc-3935	160	11	51	51	NUM
dpc-3935	160	12	ye	ye	NOUN
dpc-3935	160	13	s	s	NOUN
dpc-3935	160	14	4	4	NUM
dpc-3935	160	15	3	3	NUM
dpc-3935	160	16	m	m	NOUN
dpc-3935	160	17	it	it	PRON
dpc-3935	160	18	f	f	NOUN
dpc-3935	160	19	n	n	INTJ
dpc-3935	160	20	m	m	VERB
dpc-3935	160	21	_	_	NOUN
dpc-3935	160	22	0	0	NUM
dpc-3935	160	23	00	00	NUM
dpc-3935	160	24	24	24	NUM
dpc-3935	160	25	8	8	NUM
dpc-3935	160	26	.	.	PUNCT
dpc-3935	161	1	4	4	NUM
dpc-3935	161	2	:	:	PUNCT
dpc-3935	161	3	c.	c.	NOUN
dpc-3935	161	4	95	95	NUM
dpc-3935	161	5	2	2	NUM
dpc-3935	161	6	g	g	NOUN
dpc-3935	161	7	>	>	X
dpc-3935	161	8	a	a	DET
dpc-3935	161	9	p.	p.	NOUN
dpc-3935	161	10	g	g	PROPN
dpc-3935	161	11	lu	lu	PROPN
dpc-3935	161	12	31	31	NUM
dpc-3935	161	13	8l	8l	NOUN
dpc-3935	161	14	ys	ys	INTJ
dpc-3935	161	15	pv	pv	INTJ
dpc-3935	161	16	#	#	SYM
dpc-3935	161	17	3	3	NUM
dpc-3935	161	18	5	5	NUM
dpc-3935	161	19	2	2	NUM
dpc-3935	161	20	7	7	NUM
dpc-3935	161	21	44	44	NUM
dpc-3935	161	22	no	no	DET
dpc-3935	161	23	3	3	NUM
dpc-3935	161	24	3	3	NUM
dpc-3935	161	25	c	c	NOUN
dpc-3935	161	26	d	d	X
dpc-3935	161	27	k	k	PROPN
dpc-3935	161	28	n	n	PROPN
dpc-3935	161	29	2a	2a	NUM
dpc-3935	161	30	n	n	PRON
dpc-3935	161	31	m	m	NOUN
dpc-3935	162	1	_	_	NOUN
dpc-3935	162	2	0	0	PUNCT
dpc-3935	162	3	00	00	NUM
dpc-3935	162	4	07	07	NUM
dpc-3935	162	5	7	7	NUM
dpc-3935	162	6	.	.	NOUN
dpc-3935	162	7	5	5	NUM
dpc-3935	162	8	:	:	PUNCT
dpc-3935	162	9	c.	c.	NOUN
dpc-3935	162	10	30	30	NUM
dpc-3935	162	11	1	1	NUM
dpc-3935	162	12	g	g	NOUN
dpc-3935	162	13	>	>	X
dpc-3935	162	14	t	t	PROPN
dpc-3935	163	1	p.	p.	NOUN
dpc-3935	163	2	g	g	NOUN
dpc-3935	164	1	ly	ly	ADP
dpc-3935	164	2	10	10	NUM
dpc-3935	164	3	1	1	NUM
dpc-3935	164	4	t	t	NOUN
dpc-3935	164	5	rp	rp	NOUN
dpc-3935	164	6	pv	pv	INTJ
dpc-3935	164	7	fh	fh	PROPN
dpc-3935	165	1	=	=	PUNCT
dpc-3935	165	2	f	f	PROPN
dpc-3935	165	3	am	be	AUX
dpc-3935	165	4	ily	ily	ADV
dpc-3935	165	5	h	h	NOUN
dpc-3935	165	6	is	be	AUX
dpc-3935	165	7	to	to	PART
dpc-3935	165	8	ry	ry	VERB
dpc-3935	165	9	;	;	PUNCT
dpc-3935	165	10	p	p	X
dpc-3935	165	11	c	c	NOUN
dpc-3935	165	12	=	=	PUNCT
dpc-3935	165	13	p	p	X
dpc-3935	165	14	an	an	DET
dpc-3935	165	15	cr	cr	NOUN
dpc-3935	165	16	ea	ea	ADP
dpc-3935	165	17	ti	ti	PROPN
dpc-3935	166	1	c	c	PROPN
dpc-3935	166	2	ca	can	AUX
dpc-3935	166	3	nc	nc	PROPN
dpc-3935	166	4	er	er	INTJ
dpc-3935	166	5	;	;	PUNCT
dpc-3935	166	6	h	h	NOUN
dpc-3935	166	7	g	g	NOUN
dpc-3935	166	8	v	v	NOUN
dpc-3935	166	9	s	s	PART
dpc-3935	166	10	=	=	NOUN
dpc-3935	166	11	h	h	NOUN
dpc-3935	166	12	um	um	INTJ
dpc-3935	166	13	an	an	DET
dpc-3935	166	14	g	g	NOUN
dpc-3935	166	15	en	en	ADP
dpc-3935	166	16	om	om	PROPN
dpc-3935	166	17	e	e	PROPN
dpc-3935	166	18	v	v	X
dpc-3935	166	19	ar	ar	PROPN
dpc-3935	166	20	ia	ia	PROPN
dpc-3935	166	21	ti	ti	PROPN
dpc-3935	166	22	on	on	ADP
dpc-3935	166	23	s	s	X
dpc-3935	166	24	oc	oc	NOUN
dpc-3935	166	25	ie	ie	ADV
dpc-3935	166	26	ty	ty	INTJ
dpc-3935	166	27	;	;	PUNCT
dpc-3935	166	28	v	v	NUM
dpc-3935	166	29	u	u	NOUN
dpc-3935	166	30	s	s	PART
dpc-3935	166	31	=	=	PROPN
dpc-3935	166	32	va	va	PROPN
dpc-3935	166	33	ri	ri	PROPN
dpc-3935	166	34	an	an	DET
dpc-3935	166	35	t	t	NOUN
dpc-3935	166	36	of	of	ADP
dpc-3935	166	37	u	u	PROPN
dpc-3935	166	38	nk	nk	PROPN
dpc-3935	166	39	no	no	PROPN
dpc-3935	166	40	w	w	NOUN
dpc-3935	166	41	n	n	ADP
dpc-3935	166	42	cl	cl	NOUN
dpc-3935	166	43	in	in	ADP
dpc-3935	166	44	ic	ic	PROPN
dpc-3935	166	45	al	al	PROPN
dpc-3935	166	46	s	s	PROPN
dpc-3935	166	47	ig	ig	PROPN
dpc-3935	166	48	ni	ni	PROPN
dpc-3935	166	49	fi	fi	PROPN
dpc-3935	166	50	ca	ca	PROPN
dpc-3935	166	51	nc	nc	PROPN
dpc-3935	166	52	e	e	PROPN
dpc-3935	166	53	;	;	PUNCT
dpc-3935	166	54	p	p	DET
dpc-3935	166	55	v	v	NOUN
dpc-3935	166	56	=	=	SYM
dpc-3935	167	1	pa	pa	PROPN
dpc-3935	167	2	th	th	X
dpc-3935	167	3	og	og	PROPN
dpc-3935	167	4	en	en	PROPN
dpc-3935	167	5	ic	ic	PROPN
dpc-3935	167	6	v	v	PROPN
dpc-3935	167	7	ar	ar	PROPN
dpc-3935	167	8	ia	ia	PROPN
dpc-3935	168	1	nt	not	PART
dpc-3935	168	2	a	a	DET
dpc-3935	168	3	up	up	NOUN
dpc-3935	168	4	t	t	NOUN
dpc-3935	168	5	o	o	NOUN
dpc-3935	168	6	2nd	2nd	PROPN
dpc-3935	169	1	d	d	X
dpc-3935	169	2	eg	eg	NOUN
dpc-3935	169	3	re	re	NOUN
dpc-3935	169	4	e	e	NOUN
dpc-3935	169	5	;	;	PUNCT
dpc-3935	169	6	b	b	X
dpc-3935	169	7	1	1	NUM
dpc-3935	169	8	=	=	SYM
dpc-3935	169	9	<	<	X
dpc-3935	169	10	1	1	NUM
dpc-3935	169	11	0	0	NUM
dpc-3935	169	12	,	,	PUNCT
dpc-3935	169	13	2	2	NUM
dpc-3935	169	14	=	=	SYM
dpc-3935	169	15	10	10	NUM
dpc-3935	169	16	-5	-5	NUM
dpc-3935	169	17	0	0	NUM
dpc-3935	169	18	,	,	PUNCT
dpc-3935	169	19	3	3	NUM
dpc-3935	169	20	=	=	SYM
dpc-3935	169	21	50	50	NUM
dpc-3935	169	22	-1	-1	NOUN
dpc-3935	169	23	00	00	NUM
dpc-3935	169	24	,	,	PUNCT
dpc-3935	169	25	4	4	NUM
dpc-3935	169	26	=	=	SYM
dpc-3935	169	27	>	>	X
dpc-3935	169	28	1	1	NUM
dpc-3935	169	29	00	00	NUM
dpc-3935	169	30	.	.	PUNCT
dpc-3935	170	1	6	6	NUM
dpc-3935	170	2	original	original	ADJ
dpc-3935	170	3	article	article	NOUN
dpc-3935	170	4	|	|	ADV
dpc-3935	170	5	dermatol	dermatol	ADJ
dpc-3935	170	6	pract	pract	NOUN
dpc-3935	170	7	concept	concept	NOUN
dpc-3935	170	8	.	.	PUNCT
dpc-3935	171	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	171	2	lower	low	ADJ
dpc-3935	171	3	than	than	ADP
dpc-3935	171	4	the	the	DET
dpc-3935	171	5	33	33	NUM
dpc-3935	171	6	%	%	NOUN
dpc-3935	171	7	detection	detection	NOUN
dpc-3935	171	8	rate	rate	NOUN
dpc-3935	171	9	in	in	ADP
dpc-3935	171	10	the	the	DET
dpc-3935	171	11	italian	italian	ADJ
dpc-3935	171	12	population	population	NOUN
dpc-3935	171	13	with	with	ADP
dpc-3935	171	14	fm	fm	PROPN
dpc-3935	171	15	reported	report	VERB
dpc-3935	171	16	in	in	ADP
dpc-3935	171	17	2009	2009	NUM
dpc-3935	171	18	by	by	ADP
dpc-3935	171	19	the	the	DET
dpc-3935	171	20	italian	italian	ADJ
dpc-3935	171	21	melanoma	melanoma	PROPN
dpc-3935	171	22	intergroup	intergroup	NOUN
dpc-3935	171	23	study	study	NOUN
dpc-3935	171	24	(	(	PUNCT
dpc-3935	171	25	25	25	NUM
dpc-3935	171	26	%	%	NOUN
dpc-3935	171	27	in	in	ADP
dpc-3935	171	28	families	family	NOUN
dpc-3935	171	29	with	with	ADP
dpc-3935	171	30	2	2	NUM
dpc-3935	171	31	melanomas	melanoma	NOUN
dpc-3935	171	32	and	and	CCONJ
dpc-3935	171	33	46	46	NUM
dpc-3935	171	34	%	%	NOUN
dpc-3935	171	35	in	in	ADP
dpc-3935	171	36	families	family	NOUN
dpc-3935	171	37	with	with	ADP
dpc-3935	171	38	3	3	NUM
dpc-3935	171	39	melanomas	melanoma	NOUN
dpc-3935	171	40	)	)	PUNCT
dpc-3935	172	1	[	[	X
dpc-3935	172	2	13	13	NUM
dpc-3935	172	3	]	]	PUNCT
dpc-3935	172	4	and	and	CCONJ
dpc-3935	172	5	with	with	ADP
dpc-3935	172	6	a	a	DET
dpc-3935	172	7	detection	detection	NOUN
dpc-3935	172	8	rate	rate	NOUN
dpc-3935	172	9	of	of	ADP
dpc-3935	172	10	29.6	29.6	NUM
dpc-3935	172	11	%	%	NOUN
dpc-3935	172	12	in	in	ADP
dpc-3935	172	13	the	the	DET
dpc-3935	172	14	population	population	NOUN
dpc-3935	172	15	with	with	ADP
dpc-3935	172	16	three	three	NUM
dpc-3935	172	17	or	or	CCONJ
dpc-3935	172	18	more	more	ADJ
dpc-3935	172	19	melanomas	melanomas	NOUN
dpc-3935	172	20	reported	report	VERB
dpc-3935	172	21	in	in	ADP
dpc-3935	172	22	2016	2016	NUM
dpc-3935	172	23	by	by	ADP
dpc-3935	172	24	the	the	DET
dpc-3935	172	25	same	same	ADJ
dpc-3935	172	26	group	group	NOUN
dpc-3935	173	1	[	[	X
dpc-3935	173	2	6	6	NUM
dpc-3935	173	3	]	]	PUNCT
dpc-3935	173	4	.	.	PUNCT
dpc-3935	174	1	interestingly	interestingly	ADV
dpc-3935	174	2	,	,	PUNCT
dpc-3935	174	3	the	the	DET
dpc-3935	174	4	authors	author	NOUN
dpc-3935	174	5	selected	select	VERB
dpc-3935	174	6	patients	patient	NOUN
dpc-3935	174	7	according	accord	VERB
dpc-3935	174	8	to	to	ADP
dpc-3935	174	9	italian	italian	ADJ
dpc-3935	174	10	society	society	NOUN
dpc-3935	174	11	of	of	ADP
dpc-3935	174	12	human	human	ADJ
dpc-3935	174	13	genetics	genetic	NOUN
dpc-3935	174	14	recommendations	recommendation	NOUN
dpc-3935	174	15	,	,	PUNCT
dpc-3935	174	16	using	use	VERB
dpc-3935	174	17	less	less	ADV
dpc-3935	174	18	stringent	stringent	ADJ
dpc-3935	174	19	clinical	clinical	ADJ
dpc-3935	174	20	criteria	criterion	NOUN
dpc-3935	174	21	(	(	PUNCT
dpc-3935	174	22	≥	≥	NOUN
dpc-3935	174	23	2	2	NUM
dpc-3935	174	24	melanomas	melanoma	NOUN
dpc-3935	174	25	in	in	ADP
dpc-3935	174	26	a	a	DET
dpc-3935	174	27	single	single	ADJ
dpc-3935	174	28	patient	patient	NOUN
dpc-3935	174	29	or	or	CCONJ
dpc-3935	174	30	within	within	ADP
dpc-3935	174	31	the	the	DET
dpc-3935	174	32	same	same	ADJ
dpc-3935	174	33	family	family	NOUN
dpc-3935	174	34	lineage	lineage	NOUN
dpc-3935	174	35	regardless	regardless	ADV
dpc-3935	174	36	of	of	ADP
dpc-3935	174	37	age	age	NOUN
dpc-3935	174	38	at	at	ADP
dpc-3935	174	39	diagnosis	diagnosis	NOUN
dpc-3935	174	40	)	)	PUNCT
dpc-3935	174	41	than	than	ADP
dpc-3935	174	42	those	those	PRON
dpc-3935	174	43	employed	employ	VERB
dpc-3935	174	44	in	in	ADP
dpc-3935	174	45	this	this	DET
dpc-3935	174	46	study	study	NOUN
dpc-3935	174	47	.	.	PUNCT
dpc-3935	175	1	these	these	DET
dpc-3935	175	2	and	and	CCONJ
dpc-3935	175	3	other	other	ADJ
dpc-3935	175	4	italian	italian	ADJ
dpc-3935	175	5	studies	study	NOUN
dpc-3935	175	6	[	[	X
dpc-3935	175	7	6,13	6,13	NOUN
dpc-3935	175	8	]	]	PUNCT
dpc-3935	175	9	reported	report	VERB
dpc-3935	175	10	a	a	DET
dpc-3935	175	11	cdkn2a	cdkn2a	PROPN
dpc-3935	175	12	mutation	mutation	NOUN
dpc-3935	175	13	rate	rate	NOUN
dpc-3935	175	14	of	of	ADP
dpc-3935	175	15	8.2	8.2	NUM
dpc-3935	175	16	%	%	NOUN
dpc-3935	175	17	in	in	ADP
dpc-3935	175	18	patients	patient	NOUN
dpc-3935	175	19	with	with	ADP
dpc-3935	175	20	two	two	NUM
dpc-3935	175	21	melanomas	melanoma	NOUN
dpc-3935	175	22	,	,	PUNCT
dpc-3935	175	23	17.6	17.6	NUM
dpc-3935	175	24	%	%	NOUN
dpc-3935	175	25	in	in	ADP
dpc-3935	175	26	patients	patient	NOUN
dpc-3935	175	27	with	with	ADP
dpc-3935	175	28	three	three	NUM
dpc-3935	175	29	or	or	CCONJ
dpc-3935	175	30	more	more	ADJ
dpc-3935	175	31	melanomas	melanoma	NOUN
dpc-3935	175	32	,	,	PUNCT
dpc-3935	175	33	36.6	36.6	NUM
dpc-3935	175	34	%	%	NOUN
dpc-3935	175	35	in	in	ADP
dpc-3935	175	36	patients	patient	NOUN
dpc-3935	175	37	with	with	ADP
dpc-3935	175	38	fm	fm	PROPN
dpc-3935	175	39	and	and	CCONJ
dpc-3935	175	40	two	two	NUM
dpc-3935	175	41	melanomas	melanoma	NOUN
dpc-3935	175	42	,	,	PUNCT
dpc-3935	175	43	58.8	58.8	NUM
dpc-3935	175	44	%	%	NOUN
dpc-3935	175	45	in	in	ADP
dpc-3935	175	46	patients	patient	NOUN
dpc-3935	175	47	with	with	ADP
dpc-3935	175	48	fm	fm	PROPN
dpc-3935	175	49	,	,	PUNCT
dpc-3935	175	50	and	and	CCONJ
dpc-3935	175	51	three	three	NUM
dpc-3935	175	52	or	or	CCONJ
dpc-3935	175	53	more	more	ADJ
dpc-3935	175	54	melanomas	melanoma	NOUN
dpc-3935	175	55	,	,	PUNCT
dpc-3935	175	56	of	of	ADP
dpc-3935	175	57	25	25	NUM
dpc-3935	175	58	%	%	NOUN
dpc-3935	175	59	in	in	ADP
dpc-3935	175	60	families	family	NOUN
dpc-3935	175	61	with	with	ADP
dpc-3935	175	62	two	two	NUM
dpc-3935	175	63	affected	affected	ADJ
dpc-3935	175	64	members	member	NOUN
dpc-3935	175	65	,	,	PUNCT
dpc-3935	175	66	and	and	CCONJ
dpc-3935	175	67	of	of	ADP
dpc-3935	175	68	46	46	NUM
dpc-3935	175	69	%	%	NOUN
dpc-3935	175	70	in	in	ADP
dpc-3935	175	71	families	family	NOUN
dpc-3935	175	72	with	with	ADP
dpc-3935	175	73	three	three	NUM
dpc-3935	175	74	affected	affected	ADJ
dpc-3935	175	75	members	member	NOUN
dpc-3935	175	76	.	.	PUNCT
dpc-3935	176	1	in	in	ADP
dpc-3935	176	2	a	a	DET
dpc-3935	176	3	study	study	NOUN
dpc-3935	176	4	on	on	ADP
dpc-3935	176	5	multiple	multiple	ADJ
dpc-3935	176	6	melanomas	melanomas	NOUN
dpc-3935	176	7	in	in	ADP
dpc-3935	176	8	the	the	DET
dpc-3935	176	9	veneto	veneto	NOUN
dpc-3935	176	10	region	region	NOUN
dpc-3935	176	11	,	,	PUNCT
dpc-3935	176	12	the	the	DET
dpc-3935	176	13	detection	detection	NOUN
dpc-3935	176	14	rate	rate	NOUN
dpc-3935	176	15	of	of	ADP
dpc-3935	176	16	the	the	DET
dpc-3935	176	17	cdkn2a	cdkn2a	PROPN
dpc-3935	176	18	pv	pv	NOUN
dpc-3935	176	19	for	for	ADP
dpc-3935	176	20	multiple	multiple	ADJ
dpc-3935	176	21	melanomas	melanoma	NOUN
dpc-3935	176	22	was	be	AUX
dpc-3935	176	23	12	12	NUM
dpc-3935	176	24	%	%	NOUN
dpc-3935	176	25	[	[	X
dpc-3935	176	26	10	10	NUM
dpc-3935	176	27	]	]	PUNCT
dpc-3935	176	28	.	.	PUNCT
dpc-3935	177	1	although	although	SCONJ
dpc-3935	177	2	these	these	DET
dpc-3935	177	3	studies	study	NOUN
dpc-3935	177	4	indicate	indicate	VERB
dpc-3935	177	5	a	a	DET
dpc-3935	177	6	high	high	ADJ
dpc-3935	177	7	prevalence	prevalence	NOUN
dpc-3935	177	8	of	of	ADP
dpc-3935	177	9	cdkn2a	cdkn2a	PROPN
dpc-3935	177	10	pv	pv	VERB
dpc-3935	177	11	among	among	ADP
dpc-3935	177	12	fm	fm	PROPN
dpc-3935	177	13	cases	case	NOUN
dpc-3935	177	14	in	in	ADP
dpc-3935	177	15	italy	italy	PROPN
dpc-3935	177	16	,	,	PUNCT
dpc-3935	177	17	a	a	DET
dpc-3935	177	18	recent	recent	ADJ
dpc-3935	177	19	italian	italian	ADJ
dpc-3935	177	20	study	study	NOUN
dpc-3935	177	21	showed	show	VERB
dpc-3935	177	22	a	a	DET
dpc-3935	177	23	remarkably	remarkably	ADV
dpc-3935	177	24	lower	low	ADJ
dpc-3935	177	25	prevalence	prevalence	NOUN
dpc-3935	177	26	of	of	ADP
dpc-3935	177	27	pv	pv	NOUN
dpc-3935	177	28	(	(	PUNCT
dpc-3935	177	29	9.47	9.47	NUM
dpc-3935	177	30	%	%	NOUN
dpc-3935	177	31	)	)	PUNCT
dpc-3935	177	32	,	,	PUNCT
dpc-3935	177	33	considering	consider	VERB
dpc-3935	177	34	either	either	CCONJ
dpc-3935	177	35	cdkn2a	cdkn2a	PROPN
dpc-3935	177	36	alone	alone	ADJ
dpc-3935	177	37	or	or	CCONJ
dpc-3935	177	38	the	the	DET
dpc-3935	177	39	whole	whole	ADJ
dpc-3935	177	40	gene	gene	NOUN
dpc-3935	177	41	panel	panel	NOUN
dpc-3935	177	42	[	[	X
dpc-3935	177	43	14	14	NUM
dpc-3935	177	44	]	]	X
dpc-3935	177	45	,	,	PUNCT
dpc-3935	177	46	close	close	ADJ
dpc-3935	177	47	to	to	ADP
dpc-3935	177	48	the	the	DET
dpc-3935	177	49	findings	finding	NOUN
dpc-3935	177	50	of	of	ADP
dpc-3935	177	51	our	our	PRON
dpc-3935	177	52	study	study	NOUN
dpc-3935	177	53	.	.	PUNCT
dpc-3935	178	1	the	the	DET
dpc-3935	178	2	authors	author	NOUN
dpc-3935	178	3	suggested	suggest	VERB
dpc-3935	178	4	that	that	SCONJ
dpc-3935	178	5	,	,	PUNCT
dpc-3935	178	6	in	in	ADP
dpc-3935	178	7	the	the	DET
dpc-3935	178	8	absence	absence	NOUN
dpc-3935	178	9	of	of	ADP
dpc-3935	178	10	a	a	DET
dpc-3935	178	11	diagnosis	diagnosis	NOUN
dpc-3935	178	12	of	of	ADP
dpc-3935	178	13	at	at	ADV
dpc-3935	178	14	least	least	ADV
dpc-3935	178	15	three	three	NUM
dpc-3935	178	16	primary	primary	ADJ
dpc-3935	178	17	melanomas	melanomas	NOUN
dpc-3935	178	18	,	,	PUNCT
dpc-3935	178	19	personal	personal	ADJ
dpc-3935	178	20	/	/	SYM
dpc-3935	178	21	family	family	NOUN
dpc-3935	178	22	history	history	NOUN
dpc-3935	178	23	of	of	ADP
dpc-3935	178	24	pc	pc	NOUN
dpc-3935	178	25	,	,	PUNCT
dpc-3935	178	26	and	and	CCONJ
dpc-3935	178	27	in	in	ADP
dpc-3935	178	28	patients	patient	NOUN
dpc-3935	178	29	with	with	ADP
dpc-3935	178	30	predictors	predictor	NOUN
dpc-3935	178	31	of	of	ADP
dpc-3935	178	32	genetic	genetic	ADJ
dpc-3935	178	33	predisposition	predisposition	NOUN
dpc-3935	178	34	we	we	PRON
dpc-3935	178	35	evaluated	evaluate	VERB
dpc-3935	178	36	the	the	DET
dpc-3935	178	37	patient	patient	ADJ
dpc-3935	178	38	phenotype	phenotype	NOUN
dpc-3935	178	39	(	(	PUNCT
dpc-3935	178	40	number	number	NOUN
dpc-3935	178	41	of	of	ADP
dpc-3935	178	42	nevi	nevi	NOUN
dpc-3935	178	43	and	and	CCONJ
dpc-3935	178	44	melanomas	melanomas	NOUN
dpc-3935	178	45	,	,	PUNCT
dpc-3935	178	46	age	age	NOUN
dpc-3935	178	47	of	of	ADP
dpc-3935	178	48	first	first	ADJ
dpc-3935	178	49	melanoma	melanoma	ADJ
dpc-3935	178	50	diagnosis	diagnosis	NOUN
dpc-3935	178	51	)	)	PUNCT
dpc-3935	178	52	and	and	CCONJ
dpc-3935	178	53	family	family	NOUN
dpc-3935	178	54	history	history	NOUN
dpc-3935	178	55	of	of	ADP
dpc-3935	178	56	pc	pc	NOUN
dpc-3935	178	57	and	and	CCONJ
dpc-3935	178	58	melanoma	melanoma	NOUN
dpc-3935	178	59	among	among	ADP
dpc-3935	178	60	1stand	1stand	NUM
dpc-3935	178	61	2nd	2nd	ADJ
dpc-3935	178	62	-	-	PUNCT
dpc-3935	178	63	degree	degree	NOUN
dpc-3935	178	64	relatives	relative	NOUN
dpc-3935	178	65	as	as	ADP
dpc-3935	178	66	clinical	clinical	ADJ
dpc-3935	178	67	predictors	predictor	NOUN
dpc-3935	178	68	of	of	ADP
dpc-3935	178	69	the	the	DET
dpc-3935	178	70	presence	presence	NOUN
dpc-3935	178	71	of	of	ADP
dpc-3935	178	72	a	a	DET
dpc-3935	178	73	genetic	genetic	ADJ
dpc-3935	178	74	predisposition	predisposition	NOUN
dpc-3935	178	75	to	to	ADP
dpc-3935	178	76	melanoma	melanoma	VERB
dpc-3935	178	77	.	.	PUNCT
dpc-3935	179	1	as	as	SCONJ
dpc-3935	179	2	shown	show	VERB
dpc-3935	179	3	in	in	ADP
dpc-3935	179	4	table	table	NOUN
dpc-3935	179	5	2	2	NUM
dpc-3935	179	6	,	,	PUNCT
dpc-3935	179	7	three	three	NUM
dpc-3935	179	8	out	out	ADP
dpc-3935	179	9	of	of	ADP
dpc-3935	179	10	the	the	DET
dpc-3935	179	11	four	four	NUM
dpc-3935	179	12	patients	patient	NOUN
dpc-3935	179	13	harboring	harbor	VERB
dpc-3935	179	14	cdkn2a	cdkn2a	PUNCT
dpc-3935	179	15	or	or	CCONJ
dpc-3935	179	16	mitf	mitf	ADJ
dpc-3935	179	17	pv	pv	NOUN
dpc-3935	179	18	had	have	VERB
dpc-3935	179	19	a	a	DET
dpc-3935	179	20	positive	positive	ADJ
dpc-3935	179	21	family	family	NOUN
dpc-3935	179	22	history	history	NOUN
dpc-3935	179	23	of	of	ADP
dpc-3935	179	24	pc	pc	NOUN
dpc-3935	179	25	(	(	PUNCT
dpc-3935	179	26	75	75	NUM
dpc-3935	179	27	%	%	NOUN
dpc-3935	179	28	)	)	PUNCT
dpc-3935	179	29	,	,	PUNCT
dpc-3935	179	30	whereas	whereas	SCONJ
dpc-3935	179	31	,	,	PUNCT
dpc-3935	179	32	among	among	ADP
dpc-3935	179	33	31	31	NUM
dpc-3935	179	34	patients	patient	NOUN
dpc-3935	179	35	without	without	ADP
dpc-3935	179	36	pv	pv	INTJ
dpc-3935	179	37	in	in	ADP
dpc-3935	179	38	tested	test	VERB
dpc-3935	179	39	genes	gene	NOUN
dpc-3935	179	40	,	,	PUNCT
dpc-3935	179	41	five	five	NUM
dpc-3935	179	42	had	have	VERB
dpc-3935	179	43	a	a	DET
dpc-3935	179	44	1stor	1stor	NUM
dpc-3935	179	45	2nd	2nd	ADJ
dpc-3935	179	46	-	-	PUNCT
dpc-3935	179	47	degree	degree	NOUN
dpc-3935	179	48	relative	relative	NOUN
dpc-3935	179	49	with	with	ADP
dpc-3935	179	50	pc	pc	NOUN
dpc-3935	179	51	(	(	PUNCT
dpc-3935	179	52	16.1	16.1	NUM
dpc-3935	179	53	%	%	NOUN
dpc-3935	179	54	)	)	PUNCT
dpc-3935	180	1	(	(	PUNCT
dpc-3935	180	2	p	p	X
dpc-3935	180	3	=	=	NOUN
dpc-3935	180	4	0.0302	0.0302	NUM
dpc-3935	180	5	)	)	PUNCT
dpc-3935	180	6	.	.	PUNCT
dpc-3935	181	1	in	in	ADP
dpc-3935	181	2	addition	addition	NOUN
dpc-3935	181	3	,	,	PUNCT
dpc-3935	181	4	having	have	VERB
dpc-3935	181	5	≥	≥	PRON
dpc-3935	181	6	50	50	NUM
dpc-3935	181	7	nevi	nevi	ADJ
dpc-3935	181	8	or	or	CCONJ
dpc-3935	181	9	at	at	ADP
dpc-3935	181	10	least	least	ADJ
dpc-3935	181	11	four	four	NUM
dpc-3935	181	12	melanomas	melanoma	NOUN
dpc-3935	181	13	and	and	CCONJ
dpc-3935	181	14	observing	observe	VERB
dpc-3935	181	15	≥	≥	NUM
dpc-3935	181	16	5	5	NUM
dpc-3935	181	17	melanomas	melanoma	NOUN
dpc-3935	181	18	among	among	ADP
dpc-3935	181	19	patient	patient	NOUN
dpc-3935	181	20	and	and	CCONJ
dpc-3935	181	21	1stor	1stor	NUM
dpc-3935	181	22	2nd	2nd	ADJ
dpc-3935	181	23	-	-	PUNCT
dpc-3935	181	24	degree	degree	NOUN
dpc-3935	181	25	relatives	relative	NOUN
dpc-3935	181	26	were	be	AUX
dpc-3935	181	27	statistically	statistically	ADV
dpc-3935	181	28	significantly	significantly	ADV
dpc-3935	181	29	associated	associate	VERB
dpc-3935	181	30	with	with	ADP
dpc-3935	181	31	pv	pv	NOUN
dpc-3935	181	32	in	in	ADP
dpc-3935	181	33	tested	test	VERB
dpc-3935	181	34	genes	gene	NOUN
dpc-3935	181	35	(	(	PUNCT
dpc-3935	181	36	p	p	X
dpc-3935	181	37	<	<	X
dpc-3935	181	38	0.05	0.05	NUM
dpc-3935	181	39	)	)	PUNCT
dpc-3935	181	40	,	,	PUNCT
dpc-3935	181	41	whereas	whereas	SCONJ
dpc-3935	181	42	a	a	DET
dpc-3935	181	43	personal	personal	ADJ
dpc-3935	181	44	history	history	NOUN
dpc-3935	181	45	of	of	ADP
dpc-3935	181	46	fewer	few	ADJ
dpc-3935	181	47	than	than	ADP
dpc-3935	181	48	four	four	NUM
dpc-3935	181	49	melanomas	melanoma	NOUN
dpc-3935	181	50	and	and	CCONJ
dpc-3935	181	51	a	a	DET
dpc-3935	181	52	young	young	ADJ
dpc-3935	181	53	age	age	NOUN
dpc-3935	181	54	(	(	PUNCT
dpc-3935	181	55	<	<	X
dpc-3935	181	56	45	45	NUM
dpc-3935	181	57	years	year	NOUN
dpc-3935	181	58	)	)	PUNCT
dpc-3935	181	59	at	at	ADP
dpc-3935	181	60	first	first	ADJ
dpc-3935	181	61	melanoma	melanoma	NOUN
dpc-3935	181	62	diagnosis	diagnosis	NOUN
dpc-3935	181	63	did	do	AUX
dpc-3935	181	64	not	not	PART
dpc-3935	181	65	predict	predict	VERB
dpc-3935	181	66	a	a	DET
dpc-3935	181	67	monogenic	monogenic	ADJ
dpc-3935	181	68	predisposition	predisposition	NOUN
dpc-3935	181	69	.	.	PUNCT
dpc-3935	182	1	conclusions	conclusion	NOUN
dpc-3935	182	2	given	give	VERB
dpc-3935	182	3	the	the	DET
dpc-3935	182	4	stringent	stringent	ADJ
dpc-3935	182	5	inclusion	inclusion	NOUN
dpc-3935	182	6	criteria	criterion	NOUN
dpc-3935	182	7	employed	employ	VERB
dpc-3935	182	8	,	,	PUNCT
dpc-3935	182	9	a	a	DET
dpc-3935	182	10	higher	high	ADJ
dpc-3935	182	11	percentage	percentage	NOUN
dpc-3935	182	12	of	of	ADP
dpc-3935	182	13	patients	patient	NOUN
dpc-3935	182	14	carrying	carry	VERB
dpc-3935	182	15	a	a	DET
dpc-3935	182	16	pv	pv	NOUN
dpc-3935	182	17	in	in	ADP
dpc-3935	182	18	a	a	DET
dpc-3935	182	19	melanomapredisposing	melanomapredisposing	NOUN
dpc-3935	182	20	gene	gene	NOUN
dpc-3935	182	21	was	be	AUX
dpc-3935	182	22	expected	expect	VERB
dpc-3935	182	23	in	in	ADP
dpc-3935	182	24	the	the	DET
dpc-3935	182	25	presented	present	VERB
dpc-3935	182	26	series	series	NOUN
dpc-3935	182	27	.	.	PUNCT
dpc-3935	183	1	however	however	ADV
dpc-3935	183	2	,	,	PUNCT
dpc-3935	183	3	the	the	DET
dpc-3935	183	4	detection	detection	NOUN
dpc-3935	183	5	rate	rate	NOUN
dpc-3935	183	6	was	be	AUX
dpc-3935	183	7	only	only	ADV
dpc-3935	183	8	11.4	11.4	NUM
dpc-3935	183	9	%	%	NOUN
dpc-3935	183	10	.	.	PUNCT
dpc-3935	184	1	the	the	DET
dpc-3935	184	2	prevalence	prevalence	NOUN
dpc-3935	184	3	of	of	ADP
dpc-3935	184	4	cdkn2a	cdkn2a	PROPN
dpc-3935	184	5	pv	pv	PROPN
dpc-3935	184	6	was	be	AUX
dpc-3935	184	7	8.6	8.6	NUM
dpc-3935	184	8	%	%	NOUN
dpc-3935	184	9	in	in	ADP
dpc-3935	184	10	this	this	DET
dpc-3935	184	11	study	study	NOUN
dpc-3935	184	12	and	and	CCONJ
dpc-3935	184	13	was	be	AUX
dpc-3935	184	14	18.2	18.2	NUM
dpc-3935	184	15	%	%	NOUN
dpc-3935	184	16	considering	consider	VERB
dpc-3935	184	17	patients	patient	NOUN
dpc-3935	184	18	with	with	ADP
dpc-3935	184	19	≥	≥	PROPN
dpc-3935	184	20	3	3	NUM
dpc-3935	184	21	melanomas	melanoma	NOUN
dpc-3935	184	22	and	and	CCONJ
dpc-3935	184	23	4.2	4.2	NUM
dpc-3935	184	24	%	%	NOUN
dpc-3935	184	25	in	in	ADP
dpc-3935	184	26	patients	patient	NOUN
dpc-3935	184	27	with	with	ADP
dpc-3935	184	28	1	1	NUM
dpc-3935	184	29	or	or	CCONJ
dpc-3935	184	30	2	2	NUM
dpc-3935	184	31	melanomas	melanomas	NOUN
dpc-3935	184	32	.	.	PUNCT
dpc-3935	185	1	this	this	PRON
dpc-3935	185	2	is	be	AUX
dpc-3935	185	3	remarkably	remarkably	ADV
dpc-3935	185	4	table	table	NOUN
dpc-3935	185	5	2	2	NUM
dpc-3935	185	6	.	.	PUNCT
dpc-3935	185	7	detection	detection	NOUN
dpc-3935	185	8	rate	rate	NOUN
dpc-3935	185	9	according	accord	VERB
dpc-3935	185	10	to	to	ADP
dpc-3935	185	11	patient	patient	ADJ
dpc-3935	185	12	cutaneous	cutaneous	ADJ
dpc-3935	185	13	phenotype	phenotype	NOUN
dpc-3935	185	14	and	and	CCONJ
dpc-3935	185	15	family	family	NOUN
dpc-3935	185	16	history	history	NOUN
dpc-3935	185	17	among	among	ADP
dpc-3935	185	18	firstand	firstand	NOUN
dpc-3935	185	19	second	second	ADJ
dpc-3935	185	20	-	-	PUNCT
dpc-3935	185	21	degree	degree	NOUN
dpc-3935	185	22	relatives	relative	NOUN
dpc-3935	185	23	patient	patient	VERB
dpc-3935	185	24	phenotype	phenotype	NOUN
dpc-3935	185	25	and	and	CCONJ
dpc-3935	185	26	fh	fh	PROPN
dpc-3935	185	27	pv	pv	INTJ
dpc-3935	185	28	(	(	PUNCT
dpc-3935	185	29	any	any	DET
dpc-3935	185	30	gene	gene	NOUN
dpc-3935	185	31	)	)	PUNCT
dpc-3935	185	32	,	,	PUNCT
dpc-3935	185	33	n	n	PROPN
dpc-3935	185	34	(	(	PUNCT
dpc-3935	185	35	%	%	INTJ
dpc-3935	185	36	)	)	PUNCT
dpc-3935	186	1	no	no	INTJ
dpc-3935	186	2	pv	pv	ADV
dpc-3935	186	3	,	,	PUNCT
dpc-3935	186	4	n	n	CCONJ
dpc-3935	186	5	(	(	PUNCT
dpc-3935	186	6	%	%	INTJ
dpc-3935	186	7	)	)	PUNCT
dpc-3935	186	8	total	total	NOUN
dpc-3935	186	9	,	,	PUNCT
dpc-3935	186	10	n	n	CCONJ
dpc-3935	186	11	(	(	PUNCT
dpc-3935	186	12	%	%	INTJ
dpc-3935	186	13	)	)	PUNCT
dpc-3935	186	14	two	two	NUM
dpc-3935	186	15	-	-	PUNCT
dpc-3935	186	16	sided	side	VERB
dpc-3935	186	17	fisher	fisher	PROPN
dpc-3935	186	18	exact	exact	PROPN
dpc-3935	186	19	test	test	NOUN
dpc-3935	186	20	negative	negative	ADJ
dpc-3935	186	21	family	family	NOUN
dpc-3935	186	22	history	history	NOUN
dpc-3935	186	23	of	of	ADP
dpc-3935	186	24	pc	pc	NOUN
dpc-3935	186	25	1	1	NUM
dpc-3935	186	26	(	(	PUNCT
dpc-3935	186	27	3.07	3.07	NUM
dpc-3935	186	28	%	%	NOUN
dpc-3935	186	29	)	)	PUNCT
dpc-3935	186	30	26	26	NUM
dpc-3935	186	31	(	(	PUNCT
dpc-3935	186	32	96.30	96.30	NUM
dpc-3935	186	33	%	%	NOUN
dpc-3935	186	34	)	)	PUNCT
dpc-3935	186	35	27	27	NUM
dpc-3935	186	36	(	(	PUNCT
dpc-3935	186	37	100	100	NUM
dpc-3935	186	38	%	%	NOUN
dpc-3935	186	39	)	)	PUNCT
dpc-3935	187	1	p	p	NOUN
dpc-3935	187	2	=	=	SYM
dpc-3935	187	3	0.0302	0.0302	NUM
dpc-3935	187	4	positive	positive	ADJ
dpc-3935	187	5	family	family	NOUN
dpc-3935	187	6	history	history	NOUN
dpc-3935	187	7	of	of	ADP
dpc-3935	187	8	pc	pc	NOUN
dpc-3935	187	9	3	3	NUM
dpc-3935	187	10	(	(	PUNCT
dpc-3935	187	11	37.50	37.50	NUM
dpc-3935	187	12	%	%	NOUN
dpc-3935	187	13	)	)	PUNCT
dpc-3935	187	14	5	5	NUM
dpc-3935	187	15	(	(	PUNCT
dpc-3935	187	16	62.50	62.50	NUM
dpc-3935	187	17	%	%	NOUN
dpc-3935	187	18	)	)	PUNCT
dpc-3935	187	19	8	8	NUM
dpc-3935	187	20	(	(	PUNCT
dpc-3935	187	21	100	100	NUM
dpc-3935	187	22	%	%	NOUN
dpc-3935	187	23	)	)	PUNCT
dpc-3935	187	24	personal	personal	ADJ
dpc-3935	187	25	history	history	NOUN
dpc-3935	187	26	of	of	ADP
dpc-3935	187	27	≥	≥	NOUN
dpc-3935	187	28	50	50	NUM
dpc-3935	187	29	nevi	nevi	ADJ
dpc-3935	187	30	4	4	NUM
dpc-3935	187	31	(	(	PUNCT
dpc-3935	187	32	23.53	23.53	NUM
dpc-3935	187	33	%	%	NOUN
dpc-3935	187	34	)	)	PUNCT
dpc-3935	187	35	13	13	NUM
dpc-3935	187	36	(	(	PUNCT
dpc-3935	187	37	76.47	76.47	NUM
dpc-3935	187	38	%	%	NOUN
dpc-3935	187	39	)	)	PUNCT
dpc-3935	187	40	17	17	NUM
dpc-3935	187	41	(	(	PUNCT
dpc-3935	187	42	100	100	NUM
dpc-3935	187	43	%	%	NOUN
dpc-3935	187	44	)	)	PUNCT
dpc-3935	188	1	p	p	NOUN
dpc-3935	188	2	=	=	PUNCT
dpc-3935	188	3	0.0455	0.0455	NUM
dpc-3935	188	4	personal	personal	ADJ
dpc-3935	188	5	history	history	NOUN
dpc-3935	188	6	of	of	ADP
dpc-3935	188	7	<	<	X
dpc-3935	188	8	50	50	NUM
dpc-3935	188	9	nevi	nevi	NOUN
dpc-3935	188	10	0	0	NUM
dpc-3935	189	1	(	(	PUNCT
dpc-3935	189	2	0	0	NUM
dpc-3935	189	3	%	%	NOUN
dpc-3935	189	4	)	)	PUNCT
dpc-3935	189	5	18	18	NUM
dpc-3935	189	6	(	(	PUNCT
dpc-3935	189	7	100	100	NUM
dpc-3935	189	8	%	%	NOUN
dpc-3935	189	9	)	)	PUNCT
dpc-3935	189	10	18	18	NUM
dpc-3935	189	11	(	(	PUNCT
dpc-3935	189	12	100	100	NUM
dpc-3935	189	13	%	%	NOUN
dpc-3935	189	14	)	)	PUNCT
dpc-3935	190	1	<	<	X
dpc-3935	190	2	45	45	NUM
dpc-3935	190	3	years	year	NOUN
dpc-3935	190	4	at	at	ADP
dpc-3935	190	5	first	first	ADJ
dpc-3935	190	6	melanoma	melanoma	NOUN
dpc-3935	190	7	3	3	NUM
dpc-3935	190	8	(	(	PUNCT
dpc-3935	190	9	20.00	20.00	NUM
dpc-3935	190	10	%	%	NOUN
dpc-3935	190	11	)	)	PUNCT
dpc-3935	190	12	12	12	NUM
dpc-3935	190	13	(	(	PUNCT
dpc-3935	190	14	80.00	80.00	NUM
dpc-3935	190	15	%	%	NOUN
dpc-3935	190	16	)	)	PUNCT
dpc-3935	190	17	15	15	NUM
dpc-3935	190	18	(	(	PUNCT
dpc-3935	190	19	100	100	NUM
dpc-3935	190	20	%	%	NOUN
dpc-3935	190	21	)	)	PUNCT
dpc-3935	191	1	p	p	NOUN
dpc-3935	191	2	=	=	PUNCT
dpc-3935	191	3	0.2924	0.2924	NUM
dpc-3935	191	4	≥	≥	NOUN
dpc-3935	191	5	45	45	NUM
dpc-3935	191	6	years	year	NOUN
dpc-3935	191	7	at	at	ADP
dpc-3935	191	8	first	first	ADJ
dpc-3935	191	9	melanoma	melanoma	NOUN
dpc-3935	191	10	1	1	NUM
dpc-3935	191	11	(	(	PUNCT
dpc-3935	191	12	5.00	5.00	NUM
dpc-3935	191	13	%	%	NOUN
dpc-3935	191	14	)	)	PUNCT
dpc-3935	191	15	19	19	NUM
dpc-3935	191	16	(	(	PUNCT
dpc-3935	191	17	95.00	95.00	NUM
dpc-3935	191	18	%	%	NOUN
dpc-3935	191	19	)	)	PUNCT
dpc-3935	191	20	20	20	NUM
dpc-3935	191	21	(	(	PUNCT
dpc-3935	191	22	100	100	NUM
dpc-3935	191	23	%	%	NOUN
dpc-3935	191	24	)	)	PUNCT
dpc-3935	191	25	personal	personal	ADJ
dpc-3935	191	26	history	history	NOUN
dpc-3935	191	27	of	of	ADP
dpc-3935	191	28	≥	≥	NOUN
dpc-3935	191	29	3	3	NUM
dpc-3935	191	30	melanomas	melanomas	NOUN
dpc-3935	191	31	2	2	NUM
dpc-3935	191	32	(	(	PUNCT
dpc-3935	191	33	18.18	18.18	NUM
dpc-3935	191	34	%	%	NOUN
dpc-3935	191	35	)	)	PUNCT
dpc-3935	191	36	9	9	NUM
dpc-3935	191	37	(	(	PUNCT
dpc-3935	191	38	81.82	81.82	NUM
dpc-3935	191	39	%	%	NOUN
dpc-3935	191	40	)	)	PUNCT
dpc-3935	191	41	11	11	NUM
dpc-3935	191	42	(	(	PUNCT
dpc-3935	191	43	100	100	NUM
dpc-3935	191	44	%	%	NOUN
dpc-3935	191	45	)	)	PUNCT
dpc-3935	192	1	p	p	X
dpc-3935	192	2	=	=	PUNCT
dpc-3935	192	3	0.5748	0.5748	NUM
dpc-3935	192	4	personal	personal	ADJ
dpc-3935	192	5	history	history	NOUN
dpc-3935	192	6	of	of	ADP
dpc-3935	192	7	<	<	X
dpc-3935	192	8	3	3	NUM
dpc-3935	192	9	melanomas	melanomas	NOUN
dpc-3935	192	10	2	2	NUM
dpc-3935	192	11	(	(	PUNCT
dpc-3935	192	12	8.33	8.33	NUM
dpc-3935	192	13	%	%	NOUN
dpc-3935	192	14	)	)	PUNCT
dpc-3935	192	15	22	22	NUM
dpc-3935	192	16	(	(	PUNCT
dpc-3935	192	17	91.67	91.67	NUM
dpc-3935	192	18	%	%	NOUN
dpc-3935	192	19	)	)	PUNCT
dpc-3935	192	20	24	24	NUM
dpc-3935	192	21	(	(	PUNCT
dpc-3935	192	22	100	100	NUM
dpc-3935	192	23	%	%	NOUN
dpc-3935	192	24	)	)	PUNCT
dpc-3935	192	25	personal	personal	ADJ
dpc-3935	192	26	history	history	NOUN
dpc-3935	192	27	of	of	ADP
dpc-3935	192	28	≥	≥	NOUN
dpc-3935	192	29	4	4	NUM
dpc-3935	192	30	melanomas	melanomas	NOUN
dpc-3935	192	31	2	2	NUM
dpc-3935	192	32	(	(	PUNCT
dpc-3935	192	33	100	100	NUM
dpc-3935	192	34	%	%	NOUN
dpc-3935	192	35	)	)	PUNCT
dpc-3935	192	36	0	0	NUM
dpc-3935	193	1	(	(	PUNCT
dpc-3935	193	2	0	0	NUM
dpc-3935	193	3	%	%	NOUN
dpc-3935	193	4	)	)	PUNCT
dpc-3935	193	5	2	2	NUM
dpc-3935	193	6	(	(	PUNCT
dpc-3935	193	7	100	100	NUM
dpc-3935	193	8	%	%	NOUN
dpc-3935	193	9	)	)	PUNCT
dpc-3935	194	1	p	p	X
dpc-3935	194	2	=	=	PUNCT
dpc-3935	194	3	0.0101	0.0101	NUM
dpc-3935	194	4	personal	personal	ADJ
dpc-3935	194	5	history	history	NOUN
dpc-3935	194	6	of	of	ADP
dpc-3935	194	7	<	<	X
dpc-3935	194	8	4	4	NUM
dpc-3935	194	9	melanomas	melanomas	NOUN
dpc-3935	194	10	2	2	NUM
dpc-3935	194	11	(	(	PUNCT
dpc-3935	194	12	6.06	6.06	NUM
dpc-3935	194	13	%	%	NOUN
dpc-3935	194	14	)	)	PUNCT
dpc-3935	194	15	31	31	NUM
dpc-3935	194	16	(	(	PUNCT
dpc-3935	194	17	93.94	93.94	NUM
dpc-3935	194	18	%	%	NOUN
dpc-3935	194	19	)	)	PUNCT
dpc-3935	194	20	33	33	NUM
dpc-3935	194	21	(	(	PUNCT
dpc-3935	194	22	100	100	NUM
dpc-3935	194	23	%	%	NOUN
dpc-3935	194	24	)	)	PUNCT
dpc-3935	194	25	personal	personal	ADJ
dpc-3935	194	26	history	history	NOUN
dpc-3935	194	27	/	/	SYM
dpc-3935	194	28	family	family	NOUN
dpc-3935	194	29	history	history	NOUN
dpc-3935	194	30	of	of	ADP
dpc-3935	194	31	≥	≥	NOUN
dpc-3935	194	32	4	4	NUM
dpc-3935	194	33	melanomas	melanomas	NOUN
dpc-3935	194	34	3	3	NUM
dpc-3935	194	35	(	(	PUNCT
dpc-3935	194	36	27.27	27.27	NUM
dpc-3935	194	37	%	%	NOUN
dpc-3935	194	38	)	)	PUNCT
dpc-3935	194	39	8	8	NUM
dpc-3935	194	40	(	(	PUNCT
dpc-3935	194	41	72.73	72.73	NUM
dpc-3935	194	42	%	%	NOUN
dpc-3935	194	43	)	)	PUNCT
dpc-3935	194	44	11	11	NUM
dpc-3935	194	45	(	(	PUNCT
dpc-3935	194	46	100	100	NUM
dpc-3935	194	47	%	%	NOUN
dpc-3935	194	48	)	)	PUNCT
dpc-3935	195	1	p	p	X
dpc-3935	195	2	=	=	NOUN
dpc-3935	195	3	0.0819	0.0819	NUM
dpc-3935	195	4	personal	personal	ADJ
dpc-3935	195	5	history	history	NOUN
dpc-3935	195	6	/	/	SYM
dpc-3935	195	7	family	family	NOUN
dpc-3935	195	8	history	history	NOUN
dpc-3935	195	9	of	of	ADP
dpc-3935	195	10	<	<	X
dpc-3935	195	11	4	4	NUM
dpc-3935	195	12	melanomas	melanomas	NOUN
dpc-3935	195	13	1	1	NUM
dpc-3935	195	14	(	(	PUNCT
dpc-3935	195	15	4.17	4.17	NUM
dpc-3935	195	16	%	%	NOUN
dpc-3935	195	17	)	)	PUNCT
dpc-3935	195	18	23	23	NUM
dpc-3935	195	19	(	(	PUNCT
dpc-3935	195	20	95.83	95.83	NUM
dpc-3935	195	21	%	%	NOUN
dpc-3935	195	22	)	)	PUNCT
dpc-3935	195	23	24	24	NUM
dpc-3935	195	24	(	(	PUNCT
dpc-3935	195	25	100	100	NUM
dpc-3935	195	26	%	%	NOUN
dpc-3935	195	27	)	)	PUNCT
dpc-3935	195	28	personal	personal	ADJ
dpc-3935	195	29	history	history	NOUN
dpc-3935	195	30	/	/	SYM
dpc-3935	195	31	family	family	NOUN
dpc-3935	195	32	history	history	NOUN
dpc-3935	195	33	≥	≥	NUM
dpc-3935	195	34	5	5	NUM
dpc-3935	195	35	melanomas	melanoma	NOUN
dpc-3935	195	36	3	3	NUM
dpc-3935	195	37	(	(	PUNCT
dpc-3935	195	38	50.00	50.00	NUM
dpc-3935	195	39	%	%	NOUN
dpc-3935	195	40	)	)	PUNCT
dpc-3935	195	41	3	3	NUM
dpc-3935	195	42	(	(	PUNCT
dpc-3935	195	43	50.00	50.00	NUM
dpc-3935	195	44	%	%	NOUN
dpc-3935	195	45	)	)	PUNCT
dpc-3935	195	46	6	6	NUM
dpc-3935	195	47	(	(	PUNCT
dpc-3935	195	48	100	100	NUM
dpc-3935	195	49	%	%	NOUN
dpc-3935	195	50	)	)	PUNCT
dpc-3935	196	1	p	p	X
dpc-3935	196	2	=	=	PUNCT
dpc-3935	196	3	0.0114	0.0114	NUM
dpc-3935	196	4	personal	personal	ADJ
dpc-3935	196	5	history	history	NOUN
dpc-3935	196	6	/	/	SYM
dpc-3935	196	7	family	family	NOUN
dpc-3935	196	8	history	history	NOUN
dpc-3935	196	9	<	<	X
dpc-3935	196	10	5	5	NUM
dpc-3935	196	11	melanomas	melanoma	NOUN
dpc-3935	196	12	1	1	NUM
dpc-3935	196	13	(	(	PUNCT
dpc-3935	196	14	3.45	3.45	NUM
dpc-3935	196	15	%	%	NOUN
dpc-3935	196	16	)	)	PUNCT
dpc-3935	196	17	28	28	NUM
dpc-3935	196	18	(	(	PUNCT
dpc-3935	196	19	96.55	96.55	NUM
dpc-3935	196	20	%	%	NOUN
dpc-3935	196	21	)	)	PUNCT
dpc-3935	196	22	29	29	NUM
dpc-3935	196	23	(	(	PUNCT
dpc-3935	196	24	100	100	NUM
dpc-3935	196	25	%	%	NOUN
dpc-3935	196	26	)	)	PUNCT
dpc-3935	196	27	fh	fh	PROPN
dpc-3935	196	28	=	=	PUNCT
dpc-3935	196	29	family	family	NOUN
dpc-3935	196	30	history	history	NOUN
dpc-3935	196	31	;	;	PUNCT
dpc-3935	196	32	pc	pc	NOUN
dpc-3935	196	33	=	=	SYM
dpc-3935	196	34	pancreatic	pancreatic	NOUN
dpc-3935	196	35	cancer	cancer	NOUN
dpc-3935	196	36	;	;	PUNCT
dpc-3935	196	37	pv	pv	X
dpc-3935	196	38	=	=	NOUN
dpc-3935	196	39	pathogenic	pathogenic	ADJ
dpc-3935	196	40	variant	variant	ADJ
dpc-3935	196	41	original	original	ADJ
dpc-3935	196	42	article	article	NOUN
dpc-3935	196	43	|	|	ADV
dpc-3935	196	44	dermatol	dermatol	ADJ
dpc-3935	196	45	pract	pract	NOUN
dpc-3935	196	46	concept	concept	NOUN
dpc-3935	196	47	.	.	PUNCT
dpc-3935	197	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	197	2	7	7	NUM
dpc-3935	197	3	in	in	ADP
dpc-3935	197	4	gnomad	gnomad	ADJ
dpc-3935	197	5	database	database	NOUN
dpc-3935	197	6	,	,	PUNCT
dpc-3935	197	7	with	with	SCONJ
dpc-3935	197	8	one	one	NUM
dpc-3935	197	9	homozygote	homozygote	NOUN
dpc-3935	197	10	reported	report	VERB
dpc-3935	197	11	,	,	PUNCT
dpc-3935	197	12	the	the	DET
dpc-3935	197	13	presence	presence	NOUN
dpc-3935	197	14	of	of	ADP
dpc-3935	197	15	this	this	DET
dpc-3935	197	16	variant	variant	NOUN
dpc-3935	197	17	in	in	ADP
dpc-3935	197	18	control	control	NOUN
dpc-3935	197	19	cases	case	NOUN
dpc-3935	197	20	and	and	CCONJ
dpc-3935	197	21	its	its	PRON
dpc-3935	197	22	cosegregation	cosegregation	NOUN
dpc-3935	197	23	with	with	ADP
dpc-3935	197	24	other	other	ADJ
dpc-3935	197	25	pv	pv	NOUN
dpc-3935	197	26	strictly	strictly	ADV
dpc-3935	197	27	related	relate	VERB
dpc-3935	197	28	to	to	ADP
dpc-3935	197	29	the	the	DET
dpc-3935	197	30	observed	observed	ADJ
dpc-3935	197	31	phenotype	phenotype	NOUN
dpc-3935	197	32	in	in	ADP
dpc-3935	197	33	some	some	DET
dpc-3935	197	34	studies	study	NOUN
dpc-3935	197	35	suggests	suggest	VERB
dpc-3935	197	36	a	a	DET
dpc-3935	197	37	more	more	ADV
dpc-3935	197	38	careful	careful	ADJ
dpc-3935	197	39	classification	classification	NOUN
dpc-3935	197	40	in	in	ADP
dpc-3935	197	41	vus	vus	NOUN
dpc-3935	197	42	.	.	PUNCT
dpc-3935	198	1	no	no	DET
dpc-3935	198	2	segregation	segregation	NOUN
dpc-3935	198	3	studies	study	NOUN
dpc-3935	198	4	have	have	AUX
dpc-3935	198	5	been	be	AUX
dpc-3935	198	6	performed	perform	VERB
dpc-3935	198	7	for	for	ADP
dpc-3935	198	8	this	this	DET
dpc-3935	198	9	variant	variant	NOUN
dpc-3935	198	10	in	in	ADP
dpc-3935	198	11	our	our	PRON
dpc-3935	198	12	series	series	NOUN
dpc-3935	198	13	,	,	PUNCT
dpc-3935	198	14	but	but	CCONJ
dpc-3935	198	15	it	it	PRON
dpc-3935	198	16	is	be	AUX
dpc-3935	198	17	something	something	PRON
dpc-3935	198	18	to	to	PART
dpc-3935	198	19	take	take	VERB
dpc-3935	198	20	in	in	ADP
dpc-3935	198	21	serious	serious	ADJ
dpc-3935	198	22	account	account	NOUN
dpc-3935	198	23	for	for	ADP
dpc-3935	198	24	the	the	DET
dpc-3935	198	25	future	future	NOUN
dpc-3935	198	26	in	in	ADP
dpc-3935	198	27	order	order	NOUN
dpc-3935	198	28	to	to	PART
dpc-3935	198	29	investigate	investigate	VERB
dpc-3935	198	30	the	the	DET
dpc-3935	198	31	potential	potential	ADJ
dpc-3935	198	32	re	re	NOUN
dpc-3935	198	33	-	-	NOUN
dpc-3935	198	34	classification	classification	NOUN
dpc-3935	198	35	.	.	PUNCT
dpc-3935	199	1	in	in	ADP
dpc-3935	199	2	line	line	NOUN
dpc-3935	199	3	with	with	ADP
dpc-3935	199	4	the	the	DET
dpc-3935	199	5	findings	finding	NOUN
dpc-3935	199	6	of	of	ADP
dpc-3935	199	7	previous	previous	ADJ
dpc-3935	199	8	studies	study	NOUN
dpc-3935	199	9	[	[	X
dpc-3935	199	10	14	14	NUM
dpc-3935	199	11	]	]	PUNCT
dpc-3935	199	12	,	,	PUNCT
dpc-3935	199	13	we	we	PRON
dpc-3935	199	14	found	find	VERB
dpc-3935	199	15	a	a	DET
dpc-3935	199	16	statistically	statistically	ADV
dpc-3935	199	17	significant	significant	ADJ
dpc-3935	199	18	association	association	NOUN
dpc-3935	199	19	between	between	ADP
dpc-3935	199	20	the	the	DET
dpc-3935	199	21	presence	presence	NOUN
dpc-3935	199	22	of	of	ADP
dpc-3935	199	23	pv	pv	NOUN
dpc-3935	199	24	in	in	ADP
dpc-3935	199	25	the	the	DET
dpc-3935	199	26	panel	panel	NOUN
dpc-3935	199	27	of	of	ADP
dpc-3935	199	28	melanoma	melanoma	NOUN
dpc-3935	199	29	-	-	PUNCT
dpc-3935	199	30	predisposing	predispose	VERB
dpc-3935	199	31	genes	gene	NOUN
dpc-3935	199	32	tested	test	VERB
dpc-3935	199	33	and	and	CCONJ
dpc-3935	199	34	a	a	DET
dpc-3935	199	35	family	family	NOUN
dpc-3935	199	36	history	history	NOUN
dpc-3935	199	37	of	of	ADP
dpc-3935	199	38	pc	pc	NOUN
dpc-3935	199	39	in	in	ADP
dpc-3935	199	40	up	up	ADP
dpc-3935	199	41	to	to	PART
dpc-3935	199	42	second	second	ADJ
dpc-3935	199	43	-	-	PUNCT
dpc-3935	199	44	degree	degree	NOUN
dpc-3935	199	45	relatives	relative	NOUN
dpc-3935	199	46	(	(	PUNCT
dpc-3935	199	47	p	p	X
dpc-3935	199	48	=	=	NOUN
dpc-3935	199	49	0.0302	0.0302	NUM
dpc-3935	199	50	)	)	PUNCT
dpc-3935	199	51	.	.	PUNCT
dpc-3935	200	1	early	early	ADJ
dpc-3935	200	2	diagnosis	diagnosis	NOUN
dpc-3935	200	3	of	of	ADP
dpc-3935	200	4	pc	pc	NOUN
dpc-3935	200	5	seems	seem	VERB
dpc-3935	200	6	possible	possible	ADJ
dpc-3935	200	7	thanks	thank	NOUN
dpc-3935	200	8	to	to	ADP
dpc-3935	200	9	ongoing	ongoing	ADJ
dpc-3935	200	10	research	research	NOUN
dpc-3935	200	11	on	on	ADP
dpc-3935	200	12	surveillance	surveillance	NOUN
dpc-3935	200	13	in	in	ADP
dpc-3935	200	14	high	high	ADJ
dpc-3935	200	15	-	-	PUNCT
dpc-3935	200	16	risk	risk	NOUN
dpc-3935	200	17	individuals	individual	NOUN
dpc-3935	200	18	with	with	ADP
dpc-3935	200	19	a	a	DET
dpc-3935	200	20	hereditary	hereditary	ADJ
dpc-3935	200	21	predisposition	predisposition	NOUN
dpc-3935	200	22	.	.	PUNCT
dpc-3935	201	1	surveillance	surveillance	NOUN
dpc-3935	201	2	with	with	ADP
dpc-3935	201	3	annual	annual	ADJ
dpc-3935	201	4	magnetic	magnetic	ADJ
dpc-3935	201	5	-	-	PUNCT
dpc-3935	201	6	resonance	resonance	NOUN
dpc-3935	201	7	cholangiopancreatography	cholangiopancreatography	NOUN
dpc-3935	201	8	or	or	CCONJ
dpc-3935	201	9	endoscopic	endoscopic	ADJ
dpc-3935	201	10	ultrasound	ultrasound	NOUN
dpc-3935	201	11	is	be	AUX
dpc-3935	201	12	recommended	recommend	VERB
dpc-3935	201	13	for	for	ADP
dpc-3935	201	14	individuals	individual	NOUN
dpc-3935	201	15	with	with	ADP
dpc-3935	201	16	known	know	VERB
dpc-3935	201	17	cdkn2a	cdkn2a	PROPN
dpc-3935	201	18	pv	pv	PUNCT
dpc-3935	202	1	[	[	X
dpc-3935	202	2	15,16	15,16	NUM
dpc-3935	202	3	]	]	PUNCT
dpc-3935	202	4	starting	start	VERB
dpc-3935	202	5	from	from	ADP
dpc-3935	202	6	40	40	NUM
dpc-3935	202	7	or	or	CCONJ
dpc-3935	202	8	30	30	NUM
dpc-3935	202	9	in	in	ADP
dpc-3935	202	10	italy	italy	PROPN
dpc-3935	202	11	[	[	X
dpc-3935	202	12	29,30	29,30	NUM
dpc-3935	202	13	]	]	PUNCT
dpc-3935	202	14	.	.	PUNCT
dpc-3935	203	1	the	the	DET
dpc-3935	203	2	three	three	NUM
dpc-3935	203	3	carriers	carrier	NOUN
dpc-3935	203	4	of	of	ADP
dpc-3935	203	5	cdkn2a	cdkn2a	PROPN
dpc-3935	203	6	pv	pv	VERB
dpc-3935	203	7	in	in	ADP
dpc-3935	203	8	this	this	DET
dpc-3935	203	9	study	study	NOUN
dpc-3935	203	10	were	be	AUX
dpc-3935	203	11	referred	refer	VERB
dpc-3935	203	12	to	to	ADP
dpc-3935	203	13	centers	center	NOUN
dpc-3935	203	14	dedicated	dedicate	VERB
dpc-3935	203	15	to	to	ADP
dpc-3935	203	16	pc	pc	NOUN
dpc-3935	203	17	surveillance	surveillance	NOUN
dpc-3935	203	18	.	.	PUNCT
dpc-3935	204	1	this	this	DET
dpc-3935	204	2	study	study	NOUN
dpc-3935	204	3	has	have	VERB
dpc-3935	204	4	limitations	limitation	NOUN
dpc-3935	204	5	.	.	PUNCT
dpc-3935	205	1	first	first	ADV
dpc-3935	205	2	,	,	PUNCT
dpc-3935	205	3	it	it	PRON
dpc-3935	205	4	is	be	AUX
dpc-3935	205	5	a	a	DET
dpc-3935	205	6	small	small	ADJ
dpc-3935	205	7	study	study	NOUN
dpc-3935	205	8	,	,	PUNCT
dpc-3935	205	9	with	with	ADP
dpc-3935	205	10	only	only	ADV
dpc-3935	205	11	35	35	NUM
dpc-3935	205	12	out	out	ADP
dpc-3935	205	13	of	of	ADP
dpc-3935	205	14	46	46	NUM
dpc-3935	205	15	eligible	eligible	ADJ
dpc-3935	205	16	patients	patient	NOUN
dpc-3935	205	17	accepting	accept	VERB
dpc-3935	205	18	to	to	PART
dpc-3935	205	19	undergo	undergo	VERB
dpc-3935	205	20	genetic	genetic	ADJ
dpc-3935	205	21	counseling	counseling	NOUN
dpc-3935	205	22	and	and	CCONJ
dpc-3935	205	23	testing	testing	NOUN
dpc-3935	205	24	.	.	PUNCT
dpc-3935	206	1	moreover	moreover	ADV
dpc-3935	206	2	,	,	PUNCT
dpc-3935	206	3	while	while	SCONJ
dpc-3935	206	4	the	the	DET
dpc-3935	206	5	diagnoses	diagnosis	NOUN
dpc-3935	206	6	of	of	ADP
dpc-3935	206	7	melanoma	melanoma	NOUN
dpc-3935	206	8	in	in	ADP
dpc-3935	206	9	the	the	DET
dpc-3935	206	10	patients	patient	NOUN
dpc-3935	206	11	enrolled	enrol	VERB
dpc-3935	206	12	in	in	ADP
dpc-3935	206	13	this	this	DET
dpc-3935	206	14	study	study	NOUN
dpc-3935	206	15	were	be	AUX
dpc-3935	206	16	pathologically	pathologically	ADV
dpc-3935	206	17	confirmed	confirm	VERB
dpc-3935	206	18	,	,	PUNCT
dpc-3935	206	19	it	it	PRON
dpc-3935	206	20	was	be	AUX
dpc-3935	206	21	not	not	PART
dpc-3935	206	22	so	so	ADV
dpc-3935	206	23	for	for	ADP
dpc-3935	206	24	the	the	DET
dpc-3935	206	25	diagnoses	diagnosis	NOUN
dpc-3935	206	26	of	of	ADP
dpc-3935	206	27	pc	pc	NOUN
dpc-3935	206	28	or	or	CCONJ
dpc-3935	206	29	melanoma	melanoma	NOUN
dpc-3935	206	30	in	in	ADP
dpc-3935	206	31	family	family	NOUN
dpc-3935	206	32	members	member	NOUN
dpc-3935	206	33	and	and	CCONJ
dpc-3935	206	34	might	might	AUX
dpc-3935	206	35	not	not	PART
dpc-3935	206	36	be	be	AUX
dpc-3935	206	37	accurate	accurate	ADJ
dpc-3935	206	38	.	.	PUNCT
dpc-3935	207	1	furthermore	furthermore	ADV
dpc-3935	207	2	,	,	PUNCT
dpc-3935	207	3	the	the	DET
dpc-3935	207	4	prevalence	prevalence	NOUN
dpc-3935	207	5	of	of	ADP
dpc-3935	207	6	cdkn2a	cdkn2a	PROPN
dpc-3935	207	7	and	and	CCONJ
dpc-3935	207	8	atm	atm	ADJ
dpc-3935	207	9	pv	pv	NOUN
dpc-3935	207	10	is	be	AUX
dpc-3935	207	11	conditioned	condition	VERB
dpc-3935	207	12	by	by	ADP
dpc-3935	207	13	the	the	DET
dpc-3935	207	14	clinical	clinical	ADJ
dpc-3935	207	15	classification	classification	NOUN
dpc-3935	207	16	of	of	ADP
dpc-3935	207	17	the	the	DET
dpc-3935	207	18	cdkn2a	cdkn2a	PROPN
dpc-3935	207	19	c.150	c.150	ADJ
dpc-3935	207	20	+	+	ADJ
dpc-3935	207	21	5del	5del	PROPN
dpc-3935	207	22	variant	variant	NOUN
dpc-3935	207	23	and	and	CCONJ
dpc-3935	207	24	the	the	DET
dpc-3935	207	25	atm	atm	NOUN
dpc-3935	207	26	  	  	SPACE
dpc-3935	207	27	c.8734a	c.8734a	PROPN
dpc-3935	207	28	>	>	X
dpc-3935	207	29	g	g	PROPN
dpc-3935	207	30	(	(	PUNCT
dpc-3935	207	31	p.arg2912gly	p.arg2912gly	ADV
dpc-3935	207	32	)	)	PUNCT
dpc-3935	207	33	variant	variant	NOUN
dpc-3935	207	34	that	that	PRON
dpc-3935	207	35	is	be	AUX
dpc-3935	207	36	,	,	PUNCT
dpc-3935	207	37	at	at	ADP
dpc-3935	207	38	present	present	ADJ
dpc-3935	207	39	,	,	PUNCT
dpc-3935	207	40	unknown	unknown	ADJ
dpc-3935	207	41	.	.	PUNCT
dpc-3935	208	1	further	further	ADJ
dpc-3935	208	2	functional	functional	ADJ
dpc-3935	208	3	studies	study	NOUN
dpc-3935	208	4	,	,	PUNCT
dpc-3935	208	5	segregation	segregation	NOUN
dpc-3935	208	6	,	,	PUNCT
dpc-3935	208	7	and	and	CCONJ
dpc-3935	208	8	clinical	clinical	ADJ
dpc-3935	208	9	data	datum	NOUN
dpc-3935	208	10	of	of	ADP
dpc-3935	208	11	other	other	ADJ
dpc-3935	208	12	family	family	NOUN
dpc-3935	208	13	clusters	cluster	NOUN
dpc-3935	208	14	could	could	AUX
dpc-3935	208	15	help	help	VERB
dpc-3935	208	16	define	define	VERB
dpc-3935	208	17	the	the	DET
dpc-3935	208	18	impact	impact	NOUN
dpc-3935	208	19	of	of	ADP
dpc-3935	208	20	these	these	DET
dpc-3935	208	21	gene	gene	NOUN
dpc-3935	208	22	variants	variant	NOUN
dpc-3935	208	23	.	.	PUNCT
dpc-3935	209	1	upon	upon	SCONJ
dpc-3935	209	2	reviewing	review	VERB
dpc-3935	209	3	the	the	DET
dpc-3935	209	4	obtained	obtain	VERB
dpc-3935	209	5	results	result	NOUN
dpc-3935	209	6	,	,	PUNCT
dpc-3935	209	7	according	accord	VERB
dpc-3935	209	8	to	to	ADP
dpc-3935	209	9	recent	recent	ADJ
dpc-3935	209	10	data	datum	NOUN
dpc-3935	209	11	from	from	ADP
dpc-3935	209	12	the	the	DET
dpc-3935	209	13	italian	italian	ADJ
dpc-3935	209	14	melanoma	melanoma	NOUN
dpc-3935	209	15	intergroup	intergroup	NOUN
dpc-3935	209	16	,	,	PUNCT
dpc-3935	209	17	we	we	PRON
dpc-3935	209	18	believe	believe	VERB
dpc-3935	209	19	that	that	SCONJ
dpc-3935	209	20	clinical	clinical	ADJ
dpc-3935	209	21	criteria	criterion	NOUN
dpc-3935	209	22	to	to	PART
dpc-3935	209	23	propose	propose	VERB
dpc-3935	209	24	genetic	genetic	ADJ
dpc-3935	209	25	counseling	counseling	NOUN
dpc-3935	209	26	and	and	CCONJ
dpc-3935	209	27	testing	testing	NOUN
dpc-3935	209	28	to	to	ADP
dpc-3935	209	29	melanoma	melanoma	NOUN
dpc-3935	209	30	patients	patient	NOUN
dpc-3935	209	31	in	in	ADP
dpc-3935	209	32	italy	italy	PROPN
dpc-3935	209	33	should	should	AUX
dpc-3935	209	34	be	be	AUX
dpc-3935	209	35	re	re	VERB
dpc-3935	209	36	-	-	VERB
dpc-3935	209	37	evaluated	evaluated	ADJ
dpc-3935	209	38	,	,	PUNCT
dpc-3935	209	39	adopting	adopt	VERB
dpc-3935	209	40	criteria	criterion	NOUN
dpc-3935	209	41	in	in	ADP
dpc-3935	209	42	use	use	NOUN
dpc-3935	209	43	in	in	ADP
dpc-3935	209	44	high	high	ADJ
dpc-3935	209	45	-	-	PUNCT
dpc-3935	209	46	incidence	incidence	NOUN
dpc-3935	209	47	melanoma	melanoma	NOUN
dpc-3935	209	48	countries	country	NOUN
dpc-3935	209	49	.	.	PUNCT
dpc-3935	210	1	moreover	moreover	ADV
dpc-3935	210	2	,	,	PUNCT
dpc-3935	210	3	despite	despite	SCONJ
dpc-3935	210	4	its	its	PRON
dpc-3935	210	5	limitations	limitation	NOUN
dpc-3935	210	6	,	,	PUNCT
dpc-3935	210	7	this	this	DET
dpc-3935	210	8	series	series	NOUN
dpc-3935	210	9	supports	support	VERB
dpc-3935	210	10	the	the	DET
dpc-3935	210	11	genetic	genetic	ADJ
dpc-3935	210	12	assessment	assessment	NOUN
dpc-3935	210	13	for	for	ADP
dpc-3935	210	14	oncological	oncological	ADJ
dpc-3935	210	15	hereditary	hereditary	ADJ
dpc-3935	210	16	predisposition	predisposition	NOUN
dpc-3935	210	17	in	in	ADP
dpc-3935	210	18	melanoma	melanoma	NOUN
dpc-3935	210	19	patients	patient	NOUN
dpc-3935	210	20	with	with	ADP
dpc-3935	210	21	a	a	DET
dpc-3935	210	22	positive	positive	ADJ
dpc-3935	210	23	family	family	NOUN
dpc-3935	210	24	history	history	NOUN
dpc-3935	210	25	of	of	ADP
dpc-3935	210	26	pc	pc	NOUN
dpc-3935	210	27	up	up	ADP
dpc-3935	210	28	to	to	ADP
dpc-3935	210	29	the	the	DET
dpc-3935	210	30	2nd	2nd	ADJ
dpc-3935	210	31	degree	degree	NOUN
dpc-3935	210	32	of	of	ADP
dpc-3935	210	33	kinship	kinship	NOUN
dpc-3935	210	34	.	.	PUNCT
dpc-3935	211	1	references	reference	NOUN
dpc-3935	211	2	1	1	NUM
dpc-3935	211	3	.	.	PUNCT
dpc-3935	212	1	truderung	truderung	PROPN
dpc-3935	212	2	oa	oa	PROPN
dpc-3935	212	3	,	,	PUNCT
dpc-3935	212	4	sagi	sagi	PROPN
dpc-3935	212	5	jc	jc	PROPN
dpc-3935	212	6	,	,	PUNCT
dpc-3935	212	7	semsei	semsei	VERB
dpc-3935	212	8	af	af	PROPN
dpc-3935	212	9	,	,	PUNCT
dpc-3935	212	10	szalai	szalai	PROPN
dpc-3935	212	11	c.	c.	PROPN
dpc-3935	212	12	melanoma	melanoma	PROPN
dpc-3935	212	13	susceptibility	susceptibility	NOUN
dpc-3935	212	14	:	:	PUNCT
dpc-3935	212	15	an	an	DET
dpc-3935	212	16	update	update	NOUN
dpc-3935	212	17	on	on	ADP
dpc-3935	212	18	genetic	genetic	ADJ
dpc-3935	212	19	and	and	CCONJ
dpc-3935	212	20	epigenetic	epigenetic	ADJ
dpc-3935	212	21	findings	finding	NOUN
dpc-3935	212	22	.	.	PUNCT
dpc-3935	213	1	int	int	PROPN
dpc-3935	213	2	j	j	PROPN
dpc-3935	213	3	mol	mol	PROPN
dpc-3935	213	4	epidemiol	epidemiol	PROPN
dpc-3935	213	5	genet	genet	PROPN
dpc-3935	213	6	.	.	PUNCT
dpc-3935	214	1	2021;12(5):71	2021;12(5):71	NUM
dpc-3935	214	2	-	-	SYM
dpc-3935	214	3	89	89	NUM
dpc-3935	214	4	.	.	PUNCT
dpc-3935	215	1	pmid	pmid	NOUN
dpc-3935	215	2	:	:	PUNCT
dpc-3935	215	3	34853632	34853632	NUM
dpc-3935	215	4	pmcid	pmcid	NOUN
dpc-3935	215	5	:	:	PUNCT
dpc-3935	215	6	pmc8611230	pmc8611230	VERB
dpc-3935	215	7	.	.	PUNCT
dpc-3935	216	1	2	2	X
dpc-3935	216	2	.	.	X
dpc-3935	216	3	garbe	garbe	PROPN
dpc-3935	216	4	c	c	PROPN
dpc-3935	216	5	,	,	PUNCT
dpc-3935	216	6	keim	keim	PROPN
dpc-3935	216	7	u	u	NOUN
dpc-3935	216	8	,	,	PUNCT
dpc-3935	216	9	gandini	gandini	VERB
dpc-3935	216	10	s	s	PROPN
dpc-3935	216	11	,	,	PUNCT
dpc-3935	216	12	et	et	PROPN
dpc-3935	216	13	al	al	PROPN
dpc-3935	216	14	.	.	PUNCT
dpc-3935	217	1	epidemiology	epidemiology	NOUN
dpc-3935	217	2	of	of	ADP
dpc-3935	217	3	cutaneous	cutaneous	ADJ
dpc-3935	217	4	melanoma	melanoma	NOUN
dpc-3935	217	5	and	and	CCONJ
dpc-3935	217	6	keratinocyte	keratinocyte	NOUN
dpc-3935	217	7	cancer	cancer	NOUN
dpc-3935	217	8	in	in	ADP
dpc-3935	217	9	white	white	ADJ
dpc-3935	217	10	populations	population	NOUN
dpc-3935	217	11	1943	1943	NUM
dpc-3935	217	12	-	-	SYM
dpc-3935	217	13	2036	2036	NUM
dpc-3935	217	14	.	.	PUNCT
dpc-3935	218	1	eur	eur	PROPN
dpc-3935	218	2	j	j	PROPN
dpc-3935	218	3	cancer	cancer	NOUN
dpc-3935	218	4	.	.	PUNCT
dpc-3935	219	1	2021;152:18	2021;152:18	NUM
dpc-3935	219	2	-	-	SYM
dpc-3935	219	3	25	25	NUM
dpc-3935	219	4	.	.	PUNCT
dpc-3935	220	1	doi	doi	NOUN
dpc-3935	220	2	:	:	PUNCT
dpc-3935	220	3	10.1016	10.1016	NUM
dpc-3935	220	4	/	/	SYM
dpc-3935	220	5	j.ejca.2021	j.ejca.2021	PROPN
dpc-3935	220	6	.04.029	.04.029	PROPN
dpc-3935	220	7	.	.	PUNCT
dpc-3935	221	1	epub	epub	NOUN
dpc-3935	221	2	2021	2021	NUM
dpc-3935	221	3	may	may	AUX
dpc-3935	221	4	29	29	NUM
dpc-3935	221	5	.	.	PUNCT
dpc-3935	222	1	pmid	pmid	NOUN
dpc-3935	222	2	:	:	PUNCT
dpc-3935	222	3	34062483	34062483	NUM
dpc-3935	222	4	.	.	PUNCT
dpc-3935	223	1	melanoma	melanoma	PROPN
dpc-3935	223	2	diagnosed	diagnose	VERB
dpc-3935	223	3	after	after	ADP
dpc-3935	223	4	60	60	NUM
dpc-3935	223	5	,	,	PUNCT
dpc-3935	223	6	the	the	DET
dpc-3935	223	7	benefit	benefit	NOUN
dpc-3935	223	8	of	of	ADP
dpc-3935	223	9	genetic	genetic	ADJ
dpc-3935	223	10	testing	testing	NOUN
dpc-3935	223	11	should	should	AUX
dpc-3935	223	12	be	be	AUX
dpc-3935	223	13	carefully	carefully	ADV
dpc-3935	223	14	evaluated	evaluate	VERB
dpc-3935	223	15	due	due	ADP
dpc-3935	223	16	to	to	ADP
dpc-3935	223	17	the	the	DET
dpc-3935	223	18	low	low	ADJ
dpc-3935	223	19	detection	detection	NOUN
dpc-3935	223	20	rate	rate	NOUN
dpc-3935	223	21	.	.	PUNCT
dpc-3935	224	1	our	our	PRON
dpc-3935	224	2	data	datum	NOUN
dpc-3935	224	3	support	support	VERB
dpc-3935	224	4	this	this	DET
dpc-3935	224	5	position	position	NOUN
dpc-3935	224	6	and	and	CCONJ
dpc-3935	224	7	emphasize	emphasize	VERB
dpc-3935	224	8	that	that	SCONJ
dpc-3935	224	9	the	the	DET
dpc-3935	224	10	inclusion	inclusion	NOUN
dpc-3935	224	11	criteria	criterion	NOUN
dpc-3935	224	12	for	for	ADP
dpc-3935	224	13	hereditary	hereditary	ADJ
dpc-3935	224	14	melanoma	melanoma	NOUN
dpc-3935	224	15	genetic	genetic	ADJ
dpc-3935	224	16	testing	testing	NOUN
dpc-3935	224	17	in	in	ADP
dpc-3935	224	18	italy	italy	PROPN
dpc-3935	224	19	may	may	AUX
dpc-3935	224	20	need	need	VERB
dpc-3935	224	21	to	to	PART
dpc-3935	224	22	be	be	AUX
dpc-3935	224	23	reconsidered	reconsider	VERB
dpc-3935	224	24	.	.	PUNCT
dpc-3935	225	1	we	we	PRON
dpc-3935	225	2	suggest	suggest	VERB
dpc-3935	225	3	that	that	SCONJ
dpc-3935	225	4	the	the	DET
dpc-3935	225	5	assessment	assessment	NOUN
dpc-3935	225	6	for	for	ADP
dpc-3935	225	7	genetic	genetic	ADJ
dpc-3935	225	8	counseling	counseling	NOUN
dpc-3935	225	9	referral	referral	NOUN
dpc-3935	225	10	should	should	AUX
dpc-3935	225	11	be	be	AUX
dpc-3935	225	12	proposed	propose	VERB
dpc-3935	225	13	with	with	ADP
dpc-3935	225	14	caution	caution	NOUN
dpc-3935	225	15	in	in	ADP
dpc-3935	225	16	cases	case	NOUN
dpc-3935	225	17	involving	involve	VERB
dpc-3935	225	18	sporadic	sporadic	ADJ
dpc-3935	225	19	multiple	multiple	ADJ
dpc-3935	225	20	melanomas	melanomas	NOUN
dpc-3935	225	21	with	with	ADP
dpc-3935	225	22	only	only	ADV
dpc-3935	225	23	two	two	NUM
dpc-3935	225	24	occurrences	occurrence	NOUN
dpc-3935	225	25	and	and	CCONJ
dpc-3935	225	26	those	those	PRON
dpc-3935	225	27	with	with	ADP
dpc-3935	225	28	a	a	DET
dpc-3935	225	29	late	late	ADJ
dpc-3935	225	30	age	age	NOUN
dpc-3935	225	31	of	of	ADP
dpc-3935	225	32	onset	onset	NOUN
dpc-3935	225	33	,	,	PUNCT
dpc-3935	225	34	especially	especially	ADV
dpc-3935	225	35	for	for	ADP
dpc-3935	225	36	patients	patient	NOUN
dpc-3935	225	37	with	with	ADP
dpc-3935	225	38	i	i	PROPN
dpc-3935	225	39	-	-	PUNCT
dpc-3935	225	40	ii	ii	PROPN
dpc-3935	225	41	skin	skin	NOUN
dpc-3935	225	42	type	type	NOUN
dpc-3935	225	43	and	and	CCONJ
dpc-3935	225	44	environmental	environmental	ADJ
dpc-3935	225	45	risk	risk	NOUN
dpc-3935	225	46	factors	factor	NOUN
dpc-3935	225	47	.	.	PUNCT
dpc-3935	226	1	we	we	PRON
dpc-3935	226	2	speculate	speculate	VERB
dpc-3935	226	3	that	that	SCONJ
dpc-3935	226	4	the	the	DET
dpc-3935	226	5	main	main	ADJ
dpc-3935	226	6	burden	burden	NOUN
dpc-3935	226	7	of	of	ADP
dpc-3935	226	8	familial/	familial/	NUM
dpc-3935	226	9	multiple	multiple	ADJ
dpc-3935	226	10	melanomas	melanomas	NOUN
dpc-3935	226	11	in	in	ADP
dpc-3935	226	12	our	our	PRON
dpc-3935	226	13	region	region	NOUN
dpc-3935	226	14	may	may	AUX
dpc-3935	226	15	be	be	AUX
dpc-3935	226	16	linked	link	VERB
dpc-3935	226	17	to	to	PART
dpc-3935	226	18	pv	pv	VERB
dpc-3935	226	19	in	in	ADP
dpc-3935	226	20	untested	untested	ADJ
dpc-3935	226	21	moderate	moderate	ADJ
dpc-3935	226	22	to	to	PART
dpc-3935	226	23	low	low	ADJ
dpc-3935	226	24	penetrance	penetrance	NOUN
dpc-3935	226	25	genes	gene	NOUN
dpc-3935	226	26	or	or	CCONJ
dpc-3935	226	27	in	in	ADP
dpc-3935	226	28	yet	yet	ADV
dpc-3935	226	29	-	-	PUNCT
dpc-3935	226	30	to	to	ADP
dpc-3935	226	31	-	-	PUNCT
dpc-3935	226	32	bediscovered	bediscovere	VERB
dpc-3935	226	33	cancer	cancer	NOUN
dpc-3935	226	34	predisposition	predisposition	NOUN
dpc-3935	226	35	genes	gene	NOUN
dpc-3935	226	36	,	,	PUNCT
dpc-3935	226	37	combined	combine	VERB
dpc-3935	226	38	with	with	ADP
dpc-3935	226	39	environmental	environmental	ADJ
dpc-3935	226	40	risk	risk	NOUN
dpc-3935	226	41	factors	factor	NOUN
dpc-3935	226	42	.	.	PUNCT
dpc-3935	227	1	in	in	ADP
dpc-3935	227	2	line	line	NOUN
dpc-3935	227	3	with	with	ADP
dpc-3935	227	4	the	the	DET
dpc-3935	227	5	literature	literature	NOUN
dpc-3935	227	6	,	,	PUNCT
dpc-3935	227	7	all	all	PRON
dpc-3935	227	8	cdkn2a	cdkn2a	PROPN
dpc-3935	227	9	deleterious	deleterious	ADJ
dpc-3935	227	10	variants	variant	NOUN
dpc-3935	227	11	identified	identify	VERB
dpc-3935	227	12	in	in	ADP
dpc-3935	227	13	our	our	PRON
dpc-3935	227	14	study	study	NOUN
dpc-3935	227	15	were	be	AUX
dpc-3935	227	16	missense	missense	NOUN
dpc-3935	227	17	variants	variant	NOUN
dpc-3935	227	18	affecting	affect	VERB
dpc-3935	227	19	p16ink4a	p16ink4a	PROPN
dpc-3935	228	1	[	[	X
dpc-3935	228	2	23	23	NUM
dpc-3935	228	3	]	]	PUNCT
dpc-3935	228	4	the	the	DET
dpc-3935	228	5	percentage	percentage	NOUN
dpc-3935	228	6	of	of	ADP
dpc-3935	228	7	patients	patient	NOUN
dpc-3935	228	8	carrying	carry	VERB
dpc-3935	228	9	mitf	mitf	NOUN
dpc-3935	228	10	pv	pv	ADV
dpc-3935	228	11	in	in	ADP
dpc-3935	228	12	this	this	DET
dpc-3935	228	13	study	study	NOUN
dpc-3935	228	14	was	be	AUX
dpc-3935	228	15	2.9	2.9	NUM
dpc-3935	228	16	%	%	NOUN
dpc-3935	228	17	,	,	PUNCT
dpc-3935	228	18	comparable	comparable	ADJ
dpc-3935	228	19	to	to	ADP
dpc-3935	228	20	data	datum	NOUN
dpc-3935	228	21	from	from	ADP
dpc-3935	228	22	the	the	DET
dpc-3935	228	23	literature	literature	NOUN
dpc-3935	228	24	[	[	X
dpc-3935	228	25	3,24	3,24	X
dpc-3935	228	26	]	]	PUNCT
dpc-3935	228	27	.	.	PUNCT
dpc-3935	229	1	mitf	mitf	PROPN
dpc-3935	229	2	is	be	AUX
dpc-3935	229	3	a	a	DET
dpc-3935	229	4	transcription	transcription	NOUN
dpc-3935	229	5	factor	factor	NOUN
dpc-3935	229	6	involved	involve	VERB
dpc-3935	229	7	in	in	ADP
dpc-3935	229	8	the	the	DET
dpc-3935	229	9	homeostasis	homeostasis	NOUN
dpc-3935	229	10	of	of	ADP
dpc-3935	229	11	melanocytes	melanocyte	NOUN
dpc-3935	229	12	and	and	CCONJ
dpc-3935	229	13	other	other	ADJ
dpc-3935	229	14	cell	cell	NOUN
dpc-3935	229	15	types	type	NOUN
dpc-3935	229	16	.	.	PUNCT
dpc-3935	230	1	mitf	mitf	VERB
dpc-3935	230	2	c.952g	c.952g	PROPN
dpc-3935	230	3	>	>	PROPN
dpc-3935	230	4	a	a	DET
dpc-3935	230	5	(	(	PUNCT
dpc-3935	230	6	p.glu318lys	p.glu318ly	NOUN
dpc-3935	230	7	)	)	PUNCT
dpc-3935	230	8	is	be	AUX
dpc-3935	230	9	a	a	DET
dpc-3935	230	10	well	well	ADV
dpc-3935	230	11	-	-	PUNCT
dpc-3935	230	12	known	know	VERB
dpc-3935	230	13	pv	pv	NOUN
dpc-3935	230	14	conferring	confer	VERB
dpc-3935	230	15	a	a	DET
dpc-3935	230	16	moderate	moderate	ADJ
dpc-3935	230	17	risk	risk	NOUN
dpc-3935	230	18	of	of	ADP
dpc-3935	230	19	developing	develop	VERB
dpc-3935	230	20	melanoma	melanoma	NOUN
dpc-3935	230	21	.	.	PUNCT
dpc-3935	231	1	moreover	moreover	ADV
dpc-3935	231	2	,	,	PUNCT
dpc-3935	231	3	multiple	multiple	ADJ
dpc-3935	231	4	primary	primary	ADJ
dpc-3935	231	5	melanomas	melanomas	NOUN
dpc-3935	231	6	,	,	PUNCT
dpc-3935	231	7	increased	increase	VERB
dpc-3935	231	8	nevus	nevus	ADJ
dpc-3935	231	9	count	count	NOUN
dpc-3935	231	10	,	,	PUNCT
dpc-3935	231	11	early	early	ADJ
dpc-3935	231	12	-	-	PUNCT
dpc-3935	231	13	onset	onset	NOUN
dpc-3935	231	14	melanoma	melanoma	NOUN
dpc-3935	231	15	,	,	PUNCT
dpc-3935	231	16	and	and	CCONJ
dpc-3935	231	17	family	family	NOUN
dpc-3935	231	18	history	history	NOUN
dpc-3935	231	19	of	of	ADP
dpc-3935	231	20	melanoma	melanoma	NOUN
dpc-3935	231	21	have	have	AUX
dpc-3935	231	22	been	be	AUX
dpc-3935	231	23	reported	report	VERB
dpc-3935	231	24	in	in	ADP
dpc-3935	231	25	carriers	carrier	NOUN
dpc-3935	231	26	of	of	ADP
dpc-3935	231	27	mitf	mitf	ADJ
dpc-3935	231	28	c.952g	c.952g	PROPN
dpc-3935	231	29	>	>	PROPN
dpc-3935	231	30	a	a	DET
dpc-3935	231	31	(	(	PUNCT
dpc-3935	231	32	p.glu318lys	p.glu318ly	NOUN
dpc-3935	231	33	)	)	PUNCT
dpc-3935	232	1	[	[	X
dpc-3935	232	2	24	24	NUM
dpc-3935	232	3	-	-	SYM
dpc-3935	232	4	26	26	NUM
dpc-3935	232	5	]	]	PUNCT
dpc-3935	232	6	.	.	PUNCT
dpc-3935	233	1	although	although	SCONJ
dpc-3935	233	2	some	some	DET
dpc-3935	233	3	authors	author	NOUN
dpc-3935	233	4	have	have	AUX
dpc-3935	233	5	suggested	suggest	VERB
dpc-3935	233	6	a	a	DET
dpc-3935	233	7	possible	possible	ADJ
dpc-3935	233	8	association	association	NOUN
dpc-3935	233	9	between	between	ADP
dpc-3935	233	10	mitf	mitf	VERB
dpc-3935	233	11	c.952g	c.952g	PROPN
dpc-3935	233	12	>	>	PROPN
dpc-3935	233	13	a	a	DET
dpc-3935	233	14	(	(	PUNCT
dpc-3935	233	15	p.glu318lys	p.glu318ly	NOUN
dpc-3935	233	16	)	)	PUNCT
dpc-3935	233	17	and	and	CCONJ
dpc-3935	233	18	pc	pc	NOUN
dpc-3935	233	19	and	and	CCONJ
dpc-3935	233	20	renal	renal	ADJ
dpc-3935	233	21	cancer	cancer	NOUN
dpc-3935	233	22	,	,	PUNCT
dpc-3935	233	23	currently	currently	ADV
dpc-3935	233	24	,	,	PUNCT
dpc-3935	233	25	there	there	PRON
dpc-3935	233	26	is	be	VERB
dpc-3935	233	27	not	not	PART
dpc-3935	233	28	sufficient	sufficient	ADJ
dpc-3935	233	29	evidence	evidence	NOUN
dpc-3935	233	30	to	to	PART
dpc-3935	233	31	support	support	VERB
dpc-3935	233	32	clinical	clinical	ADJ
dpc-3935	233	33	and	and	CCONJ
dpc-3935	233	34	radiological	radiological	ADJ
dpc-3935	233	35	surveillance	surveillance	NOUN
dpc-3935	233	36	for	for	ADP
dpc-3935	233	37	cancers	cancer	NOUN
dpc-3935	233	38	other	other	ADJ
dpc-3935	233	39	than	than	ADP
dpc-3935	233	40	melanoma	melanoma	NOUN
dpc-3935	233	41	[	[	X
dpc-3935	233	42	14,25,27,28	14,25,27,28	NUM
dpc-3935	233	43	]	]	PUNCT
dpc-3935	233	44	.	.	PUNCT
dpc-3935	234	1	focusing	focus	VERB
dpc-3935	234	2	on	on	ADP
dpc-3935	234	3	vus	vus	NOUN
dpc-3935	234	4	with	with	ADP
dpc-3935	234	5	an	an	DET
dpc-3935	234	6	interesting	interesting	ADJ
dpc-3935	234	7	potential	potential	NOUN
dpc-3935	234	8	of	of	ADP
dpc-3935	234	9	reclassification	reclassification	NOUN
dpc-3935	234	10	in	in	ADP
dpc-3935	234	11	“	"	PUNCT
dpc-3935	234	12	likely	likely	ADV
dpc-3935	234	13	pathogenic	pathogenic	ADJ
dpc-3935	234	14	”	"	PUNCT
dpc-3935	234	15	,	,	PUNCT
dpc-3935	234	16	the	the	DET
dpc-3935	234	17	c.150	c.150	ADJ
dpc-3935	234	18	+	+	ADJ
dpc-3935	234	19	5del	5del	PROPN
dpc-3935	234	20	variant	variant	NOUN
dpc-3935	234	21	falls	fall	VERB
dpc-3935	234	22	in	in	ADP
dpc-3935	234	23	intron	intron	ADJ
dpc-3935	234	24	1	1	NUM
dpc-3935	234	25	of	of	ADP
dpc-3935	234	26	the	the	DET
dpc-3935	234	27	cdkn2a	cdkn2a	ADJ
dpc-3935	234	28	gene	gene	NOUN
dpc-3935	234	29	and	and	CCONJ
dpc-3935	234	30	meets	meet	VERB
dpc-3935	234	31	criteria	criterion	NOUN
dpc-3935	234	32	for	for	ADP
dpc-3935	234	33	suspicion	suspicion	NOUN
dpc-3935	234	34	as	as	SCONJ
dpc-3935	234	35	it	it	PRON
dpc-3935	234	36	involves	involve	VERB
dpc-3935	234	37	an	an	DET
dpc-3935	234	38	intronic	intronic	ADJ
dpc-3935	234	39	deletion	deletion	NOUN
dpc-3935	234	40	,	,	PUNCT
dpc-3935	234	41	not	not	PART
dpc-3935	234	42	at	at	ADP
dpc-3935	234	43	the	the	DET
dpc-3935	234	44	splice	splice	NOUN
dpc-3935	234	45	donor	donor	NOUN
dpc-3935	234	46	/	/	SYM
dpc-3935	234	47	acceptor	acceptor	NOUN
dpc-3935	234	48	consensus	consensus	NOUN
dpc-3935	234	49	site	site	NOUN
dpc-3935	234	50	,	,	PUNCT
dpc-3935	234	51	but	but	CCONJ
dpc-3935	234	52	at	at	ADP
dpc-3935	234	53	a	a	DET
dpc-3935	234	54	nearby	nearby	ADJ
dpc-3935	234	55	site	site	NOUN
dpc-3935	234	56	.	.	PUNCT
dpc-3935	235	1	this	this	DET
dpc-3935	235	2	variant	variant	NOUN
dpc-3935	235	3	has	have	AUX
dpc-3935	235	4	been	be	AUX
dpc-3935	235	5	reported	report	VERB
dpc-3935	235	6	only	only	ADV
dpc-3935	235	7	once	once	ADV
dpc-3935	235	8	in	in	ADP
dpc-3935	235	9	global	global	ADJ
dpc-3935	235	10	genetics	genetic	NOUN
dpc-3935	235	11	databases	database	NOUN
dpc-3935	235	12	.	.	PUNCT
dpc-3935	236	1	it	it	PRON
dpc-3935	236	2	has	have	VERB
dpc-3935	236	3	suspicious	suspicious	ADJ
dpc-3935	236	4	characteristics	characteristic	NOUN
dpc-3935	236	5	confirmed	confirm	VERB
dpc-3935	236	6	by	by	ADP
dpc-3935	236	7	the	the	DET
dpc-3935	236	8	acmg	acmg	NOUN
dpc-3935	236	9	pathogenicity	pathogenicity	NOUN
dpc-3935	236	10	classification	classification	NOUN
dpc-3935	236	11	tool	tool	NOUN
dpc-3935	236	12	,	,	PUNCT
dpc-3935	236	13	which	which	PRON
dpc-3935	236	14	predicts	predict	VERB
dpc-3935	236	15	this	this	DET
dpc-3935	236	16	variant	variant	NOUN
dpc-3935	236	17	to	to	PART
dpc-3935	236	18	be	be	AUX
dpc-3935	236	19	likely	likely	ADV
dpc-3935	236	20	pathogenic	pathogenic	ADJ
dpc-3935	236	21	.	.	PUNCT
dpc-3935	237	1	together	together	ADV
dpc-3935	237	2	with	with	ADP
dpc-3935	237	3	the	the	DET
dpc-3935	237	4	patient	patient	NOUN
dpc-3935	237	5	’s	’s	PART
dpc-3935	237	6	personal	personal	ADJ
dpc-3935	237	7	and	and	CCONJ
dpc-3935	237	8	family	family	NOUN
dpc-3935	237	9	history	history	NOUN
dpc-3935	237	10	,	,	PUNCT
dpc-3935	237	11	these	these	DET
dpc-3935	237	12	elements	element	NOUN
dpc-3935	237	13	suggest	suggest	VERB
dpc-3935	237	14	a	a	DET
dpc-3935	237	15	deleterious	deleterious	ADJ
dpc-3935	237	16	effect	effect	NOUN
dpc-3935	237	17	of	of	ADP
dpc-3935	237	18	the	the	DET
dpc-3935	237	19	cdkn2a	cdkn2a	PROPN
dpc-3935	237	20	c.150	c.150	X
dpc-3935	237	21	+	+	ADJ
dpc-3935	237	22	5del	5del	PROPN
dpc-3935	237	23	variant	variant	NOUN
dpc-3935	237	24	.	.	PUNCT
dpc-3935	238	1	however	however	ADV
dpc-3935	238	2	,	,	PUNCT
dpc-3935	238	3	in	in	ADP
dpc-3935	238	4	the	the	DET
dpc-3935	238	5	absence	absence	NOUN
dpc-3935	238	6	of	of	ADP
dpc-3935	238	7	evidence	evidence	NOUN
dpc-3935	238	8	of	of	ADP
dpc-3935	238	9	the	the	DET
dpc-3935	238	10	impact	impact	NOUN
dpc-3935	238	11	of	of	ADP
dpc-3935	238	12	this	this	DET
dpc-3935	238	13	variant	variant	NOUN
dpc-3935	238	14	on	on	ADP
dpc-3935	238	15	mrna	mrna	PROPN
dpc-3935	238	16	splicing	splicing	NOUN
dpc-3935	238	17	,	,	PUNCT
dpc-3935	238	18	its	its	PRON
dpc-3935	238	19	classification	classification	NOUN
dpc-3935	238	20	remains	remain	VERB
dpc-3935	238	21	pending	pende	VERB
dpc-3935	238	22	.	.	PUNCT
dpc-3935	239	1	we	we	PRON
dpc-3935	239	2	also	also	ADV
dpc-3935	239	3	reported	report	VERB
dpc-3935	239	4	in	in	ADP
dpc-3935	239	5	a	a	DET
dpc-3935	239	6	distinct	distinct	ADJ
dpc-3935	239	7	patient	patient	NOUN
dpc-3935	239	8	the	the	DET
dpc-3935	239	9	atm	atm	NOUN
dpc-3935	239	10	 	 	SPACE
dpc-3935	239	11	c.8734a	c.8734a	PROPN
dpc-3935	239	12	>	>	X
dpc-3935	239	13	g	g	PROPN
dpc-3935	239	14	(	(	PUNCT
dpc-3935	239	15	p.arg2912gly	p.arg2912gly	ADV
dpc-3935	239	16	)	)	PUNCT
dpc-3935	239	17	variant	variant	NOUN
dpc-3935	239	18	,	,	PUNCT
dpc-3935	239	19	currently	currently	ADV
dpc-3935	239	20	classified	classify	VERB
dpc-3935	239	21	as	as	ADP
dpc-3935	239	22	a	a	DET
dpc-3935	239	23	vus	vus	NOUN
dpc-3935	239	24	.	.	PUNCT
dpc-3935	240	1	it	it	PRON
dpc-3935	240	2	is	be	AUX
dpc-3935	240	3	interesting	interesting	ADJ
dpc-3935	240	4	to	to	PART
dpc-3935	240	5	note	note	VERB
dpc-3935	240	6	that	that	SCONJ
dpc-3935	240	7	the	the	DET
dpc-3935	240	8	varsome	varsome	NOUN
dpc-3935	240	9	acmg	acmg	NOUN
dpc-3935	240	10	classification	classification	NOUN
dpc-3935	240	11	tool	tool	NOUN
dpc-3935	240	12	classifies	classify	VERB
dpc-3935	240	13	it	it	PRON
dpc-3935	240	14	as	as	ADP
dpc-3935	240	15	a	a	DET
dpc-3935	240	16	“	"	PUNCT
dpc-3935	240	17	likely	likely	ADJ
dpc-3935	240	18	pathogenic	pathogenic	ADJ
dpc-3935	240	19	”	"	PUNCT
dpc-3935	240	20	variant	variant	NOUN
dpc-3935	240	21	,	,	PUNCT
dpc-3935	240	22	based	base	VERB
dpc-3935	240	23	on	on	ADP
dpc-3935	240	24	disrupted	disrupt	VERB
dpc-3935	240	25	protein	protein	NOUN
dpc-3935	240	26	function	function	NOUN
dpc-3935	240	27	predicted	predict	VERB
dpc-3935	240	28	by	by	ADP
dpc-3935	240	29	in	in	ADP
dpc-3935	240	30	silico	silico	NOUN
dpc-3935	240	31	tools	tool	NOUN
dpc-3935	240	32	,	,	PUNCT
dpc-3935	240	33	presence	presence	NOUN
dpc-3935	240	34	of	of	ADP
dpc-3935	240	35	functional	functional	ADJ
dpc-3935	240	36	and	and	CCONJ
dpc-3935	240	37	segregation	segregation	NOUN
dpc-3935	240	38	studies	study	NOUN
dpc-3935	240	39	that	that	PRON
dpc-3935	240	40	supports	support	VERB
dpc-3935	240	41	this	this	DET
dpc-3935	240	42	prediction	prediction	NOUN
dpc-3935	240	43	,	,	PUNCT
dpc-3935	240	44	involvement	involvement	NOUN
dpc-3935	240	45	of	of	ADP
dpc-3935	240	46	a	a	DET
dpc-3935	240	47	nucleotide	nucleotide	NOUN
dpc-3935	240	48	,	,	PUNCT
dpc-3935	240	49	which	which	PRON
dpc-3935	240	50	falls	fall	VERB
dpc-3935	240	51	in	in	ADP
dpc-3935	240	52	an	an	DET
dpc-3935	240	53	hotspot	hotspot	NOUN
dpc-3935	240	54	sequence	sequence	NOUN
dpc-3935	240	55	rich	rich	ADJ
dpc-3935	240	56	of	of	ADP
dpc-3935	240	57	pvs	pvs	PROPN
dpc-3935	240	58	.	.	PUNCT
dpc-3935	241	1	however	however	ADV
dpc-3935	241	2	,	,	PUNCT
dpc-3935	241	3	its	its	PRON
dpc-3935	241	4	prevalence	prevalence	NOUN
dpc-3935	241	5	8	8	NUM
dpc-3935	241	6	original	original	ADJ
dpc-3935	241	7	article	article	NOUN
dpc-3935	241	8	|	|	ADV
dpc-3935	241	9	dermatol	dermatol	ADJ
dpc-3935	241	10	pract	pract	NOUN
dpc-3935	241	11	concept	concept	NOUN
dpc-3935	241	12	.	.	PUNCT
dpc-3935	242	1	2024;14(3):e2024120	2024;14(3):e2024120	NUM
dpc-3935	242	2	pathogenic	pathogenic	ADJ
dpc-3935	242	3	variants	variant	NOUN
dpc-3935	242	4	in	in	ADP
dpc-3935	242	5	acd	acd	PROPN
dpc-3935	242	6	,	,	PUNCT
dpc-3935	242	7	atm	atm	PROPN
dpc-3935	242	8	,	,	PUNCT
dpc-3935	242	9	bap1	bap1	PROPN
dpc-3935	242	10	,	,	PUNCT
dpc-3935	242	11	and	and	CCONJ
dpc-3935	242	12	pot1	pot1	PROPN
dpc-3935	242	13	.	.	PUNCT
dpc-3935	243	1	cancers	cancer	NOUN
dpc-3935	243	2	2020	2020	NUM
dpc-3935	243	3	,	,	PUNCT
dpc-3935	243	4	12(4	12(4	NUM
dpc-3935	243	5	)	)	PUNCT
dpc-3935	243	6	.	.	PUNCT
dpc-3935	244	1	pmid	pmid	NOUN
dpc-3935	244	2	:	:	PUNCT
dpc-3935	244	3	 	 	SPACE
dpc-3935	244	4	32325837	32325837	NUM
dpc-3935	244	5	pmcid	pmcid	NOUN
dpc-3935	244	6	:	:	PUNCT
dpc-3935	244	7	 	 	SPACE
dpc-3935	244	8	pmc7226507	pmc7226507	NOUN
dpc-3935	244	9	.	.	PUNCT
dpc-3935	245	1	18	18	NUM
dpc-3935	245	2	.	.	X
dpc-3935	245	3	bianchi	bianchi	NOUN
dpc-3935	245	4	-	-	PUNCT
dpc-3935	245	5	scarrà	scarrà	PROPN
dpc-3935	245	6	g	g	PROPN
dpc-3935	245	7	,	,	PUNCT
dpc-3935	245	8	grammatico	grammatico	PROPN
dpc-3935	245	9	m	m	PROPN
dpc-3935	245	10	,	,	PUNCT
dpc-3935	245	11	genuardi	genuardi	PROPN
dpc-3935	245	12	b	b	PROPN
dpc-3935	245	13	,	,	PUNCT
dpc-3935	245	14	et	et	PROPN
dpc-3935	245	15	al	al	PROPN
dpc-3935	245	16	.	.	PROPN
dpc-3935	245	17	raccomandazioni	raccomandazioni	PROPN
dpc-3935	245	18	per	per	ADP
dpc-3935	245	19	consulenza	consulenza	PROPN
dpc-3935	245	20	e	e	PROPN
dpc-3935	245	21	test	test	NOUN
dpc-3935	245	22	genetico	genetico	PROPN
dpc-3935	245	23	nel	nel	PROPN
dpc-3935	245	24	melanoma	melanoma	PROPN
dpc-3935	245	25	ereditario	ereditario	PROPN
dpc-3935	245	26	gruppo	gruppo	X
dpc-3935	245	27	sigu	sigu	NOUN
dpc-3935	245	28	-	-	PUNCT
dpc-3935	245	29	onc	onc	ADJ
dpc-3935	245	30	.	.	PUNCT
dpc-3935	246	1	1	1	NUM
dpc-3935	246	2	-	-	SYM
dpc-3935	246	3	6	6	NUM
dpc-3935	246	4	(	(	PUNCT
dpc-3935	246	5	2005	2005	NUM
dpc-3935	246	6	)	)	PUNCT
dpc-3935	246	7	.	.	PUNCT
dpc-3935	247	1	19	19	NUM
dpc-3935	247	2	.	.	PUNCT
dpc-3935	247	3	linee	linee	PROPN
dpc-3935	247	4	guida	guida	PROPN
dpc-3935	247	5	e	e	PROPN
dpc-3935	247	6	raccomandazioni	raccomandazioni	PROPN
dpc-3935	247	7	sidemast	sidemast	VERB
dpc-3935	247	8	https://www.sidemast	https://www.sidemast	PRON
dpc-3935	247	9	.org	.org	NOUN
dpc-3935	247	10	/	/	SYM
dpc-3935	247	11	blog	blog	PROPN
dpc-3935	247	12	/	/	SYM
dpc-3935	247	13	linee	linee	PROPN
dpc-3935	247	14	-	-	PUNCT
dpc-3935	247	15	guida	guida	PROPN
dpc-3935	247	16	-	-	PUNCT
dpc-3935	247	17	e	e	PROPN
dpc-3935	247	18	-	-	ADJ
dpc-3935	247	19	raccomandazioni	raccomandazioni	ADJ
dpc-3935	247	20	-	-	PUNCT
dpc-3935	247	21	sidemast	sidemast	NOUN
dpc-3935	247	22	.	.	PUNCT
dpc-3935	248	1	20	20	NUM
dpc-3935	248	2	.	.	PUNCT
dpc-3935	249	1	linee	linee	PROPN
dpc-3935	249	2	guida	guida	PROPN
dpc-3935	249	3	melanoma	melanoma	PROPN
dpc-3935	250	1	[	[	X
dpc-3935	250	2	https://www.aiom.it/linee-guida-aiom	https://www.aiom.it/linee-guida-aiom	X
dpc-3935	250	3	-2021	-2021	NOUN
dpc-3935	250	4	-	-	PUNCT
dpc-3935	250	5	melanoma/	melanoma/	NUM
dpc-3935	250	6	]	]	PUNCT
dpc-3935	250	7	21	21	NUM
dpc-3935	250	8	.	.	PUNCT
dpc-3935	250	9	nationelt	nationelt	PROPN
dpc-3935	250	10	vårdprogram	vårdprogram	PROPN
dpc-3935	250	11	malignt	malignt	PROPN
dpc-3935	250	12	melanom	melanom	PROPN
dpc-3935	250	13	(	(	PUNCT
dpc-3935	250	14	swedish	swedish	ADJ
dpc-3935	250	15	national	national	ADJ
dpc-3935	250	16	guidelies	guidelie	NOUN
dpc-3935	250	17	for	for	ADP
dpc-3935	250	18	malignant	malignant	ADJ
dpc-3935	250	19	melanoma	melanoma	NOUN
dpc-3935	250	20	)	)	PUNCT
dpc-3935	251	1	[	[	X
dpc-3935	251	2	https://kunskapsbanken	https://kunskapsbanken	VERB
dpc-3935	251	3	.cancercentrum.se	.cancercentrum.se	ADJ
dpc-3935	251	4	/	/	SYM
dpc-3935	251	5	diagnoser	diagnoser	NOUN
dpc-3935	251	6	/	/	SYM
dpc-3935	251	7	hudmelanom	hudmelanom	NOUN
dpc-3935	251	8	/	/	SYM
dpc-3935	251	9	vardprogram	vardprogram	PROPN
dpc-3935	251	10	/	/	SYM
dpc-3935	251	11	ladda	ladda	PROPN
dpc-3935	251	12	-ner	-ner	PUNCT
dpc-3935	251	13	-	-	PUNCT
dpc-3935	251	14	pdf/	pdf/	NOUN
dpc-3935	251	15	]	]	PUNCT
dpc-3935	252	1	22	22	NUM
dpc-3935	252	2	.	.	PUNCT
dpc-3935	253	1	ciotti	ciotti	PROPN
dpc-3935	253	2	p	p	X
dpc-3935	253	3	,	,	PUNCT
dpc-3935	253	4	struewing	struewing	ADJ
dpc-3935	253	5	jp	jp	NOUN
dpc-3935	253	6	,	,	PUNCT
dpc-3935	253	7	mantelli	mantelli	PROPN
dpc-3935	253	8	m	m	PROPN
dpc-3935	253	9	,	,	PUNCT
dpc-3935	253	10	et	et	PROPN
dpc-3935	253	11	al	al	PROPN
dpc-3935	253	12	.	.	PUNCT
dpc-3935	254	1	a	a	DET
dpc-3935	254	2	single	single	ADJ
dpc-3935	254	3	genetic	genetic	ADJ
dpc-3935	254	4	origin	origin	NOUN
dpc-3935	254	5	for	for	ADP
dpc-3935	254	6	the	the	DET
dpc-3935	254	7	g101w	g101w	PROPN
dpc-3935	254	8	cdkn2a	cdkn2a	PROPN
dpc-3935	254	9	mutation	mutation	NOUN
dpc-3935	254	10	in	in	ADP
dpc-3935	254	11	20	20	NUM
dpc-3935	254	12	melanoma	melanoma	NOUN
dpc-3935	254	13	-	-	PUNCT
dpc-3935	254	14	prone	prone	ADJ
dpc-3935	254	15	families	family	NOUN
dpc-3935	254	16	.	.	PUNCT
dpc-3935	255	1	am	be	AUX
dpc-3935	255	2	j	j	PROPN
dpc-3935	255	3	hum	hum	PROPN
dpc-3935	255	4	genet	genet	PROPN
dpc-3935	255	5	2000	2000	NUM
dpc-3935	255	6	,	,	PUNCT
dpc-3935	255	7	67(2):311	67(2):311	NOUN
dpc-3935	255	8	-	-	PUNCT
dpc-3935	255	9	319	319	NUM
dpc-3935	255	10	.	.	PUNCT
dpc-3935	256	1	pmid	pmid	NOUN
dpc-3935	256	2	:	:	PUNCT
dpc-3935	256	3	 	 	SPACE
dpc-3935	256	4	10869234	10869234	NUM
dpc-3935	256	5	pmcid	pmcid	NOUN
dpc-3935	256	6	:	:	PUNCT
dpc-3935	256	7	  	  	SPACE
dpc-3935	256	8	pmc1287180	pmc1287180	NOUN
dpc-3935	256	9	.	.	PUNCT
dpc-3935	257	1	23	23	NUM
dpc-3935	257	2	.	.	X
dpc-3935	258	1	chan	chan	PROPN
dpc-3935	258	2	sh	sh	PROPN
dpc-3935	258	3	,	,	PUNCT
dpc-3935	258	4	chiang	chiang	PROPN
dpc-3935	258	5	j	j	PROPN
dpc-3935	258	6	,	,	PUNCT
dpc-3935	258	7	ngeow	ngeow	ADP
dpc-3935	258	8	j.	j.	PROPN
dpc-3935	258	9	cdkn2a	cdkn2a	PROPN
dpc-3935	258	10	germline	germline	NOUN
dpc-3935	258	11	alterations	alteration	NOUN
dpc-3935	258	12	and	and	CCONJ
dpc-3935	258	13	the	the	DET
dpc-3935	258	14	relevance	relevance	NOUN
dpc-3935	258	15	of	of	ADP
dpc-3935	258	16	genotype	genotype	NOUN
dpc-3935	258	17	-	-	PUNCT
dpc-3935	258	18	phenotype	phenotype	NOUN
dpc-3935	258	19	associations	association	NOUN
dpc-3935	258	20	in	in	ADP
dpc-3935	258	21	cancer	cancer	NOUN
dpc-3935	258	22	predisposition	predisposition	NOUN
dpc-3935	258	23	.	.	PUNCT
dpc-3935	259	1	hered	here	VERB
dpc-3935	259	2	cancer	cancer	NOUN
dpc-3935	259	3	clin	clin	PROPN
dpc-3935	259	4	pract	pract	PROPN
dpc-3935	259	5	2021	2021	NUM
dpc-3935	259	6	,	,	PUNCT
dpc-3935	259	7	19(1):21	19(1):21	NUM
dpc-3935	259	8	.	.	PUNCT
dpc-3935	260	1	pmid	pmid	NOUN
dpc-3935	260	2	:	:	PUNCT
dpc-3935	260	3	  	  	SPACE
dpc-3935	260	4	33766116	33766116	NUM
dpc-3935	260	5	pmcid	pmcid	NOUN
dpc-3935	260	6	:	:	PUNCT
dpc-3935	260	7	 	 	SPACE
dpc-3935	260	8	pmc7992806	pmc7992806	NOUN
dpc-3935	260	9	.	.	PUNCT
dpc-3935	261	1	24	24	NUM
dpc-3935	261	2	.	.	X
dpc-3935	261	3	ciccarese	ciccarese	PROPN
dpc-3935	261	4	g	g	PROPN
dpc-3935	261	5	,	,	PUNCT
dpc-3935	261	6	dalmasso	dalmasso	NOUN
dpc-3935	261	7	b	b	PROPN
dpc-3935	261	8	,	,	PUNCT
dpc-3935	261	9	bruno	bruno	PROPN
dpc-3935	261	10	w	w	PROPN
dpc-3935	261	11	,	,	PUNCT
dpc-3935	261	12	et	et	PROPN
dpc-3935	261	13	al	al	PROPN
dpc-3935	261	14	.	.	PROPN
dpc-3935	262	1	clinical	clinical	ADJ
dpc-3935	262	2	,	,	PUNCT
dpc-3935	262	3	pathological	pathological	ADJ
dpc-3935	262	4	and	and	CCONJ
dpc-3935	262	5	dermoscopic	dermoscopic	ADJ
dpc-3935	262	6	phenotype	phenotype	NOUN
dpc-3935	262	7	of	of	ADP
dpc-3935	262	8	mitf	mitf	ADJ
dpc-3935	262	9	p.e318k	p.e318k	PROPN
dpc-3935	262	10	carrier	carrier	NOUN
dpc-3935	262	11	cutaneous	cutaneous	ADJ
dpc-3935	262	12	melanoma	melanoma	NOUN
dpc-3935	262	13	patients	patient	NOUN
dpc-3935	262	14	.	.	PUNCT
dpc-3935	263	1	j	j	PROPN
dpc-3935	263	2	transl	transl	PROPN
dpc-3935	263	3	med	med	PROPN
dpc-3935	263	4	2020	2020	NUM
dpc-3935	263	5	,	,	PUNCT
dpc-3935	264	1	18(1):78	18(1):78	NUM
dpc-3935	264	2	.	.	PUNCT
dpc-3935	265	1	pmid	pmid	NOUN
dpc-3935	265	2	:	:	PUNCT
dpc-3935	265	3	 	 	SPACE
dpc-3935	265	4	32054529	32054529	NUM
dpc-3935	265	5	pmcid	pmcid	NOUN
dpc-3935	265	6	:	:	PUNCT
dpc-3935	265	7	 	 	SPACE
dpc-3935	265	8	pmc7017513	pmc7017513	NOUN
dpc-3935	265	9	.	.	PUNCT
dpc-3935	266	1	25	25	NUM
dpc-3935	266	2	.	.	PUNCT
dpc-3935	266	3	oliveira	oliveira	PROPN
dpc-3935	266	4	ljc	ljc	PROPN
dpc-3935	266	5	,	,	PUNCT
dpc-3935	266	6	gongora	gongora	PROPN
dpc-3935	266	7	abl	abl	PROPN
dpc-3935	266	8	,	,	PUNCT
dpc-3935	266	9	lima	lima	PROPN
dpc-3935	266	10	fas	fas	PROPN
dpc-3935	266	11	,	,	PUNCT
dpc-3935	266	12	et	et	PROPN
dpc-3935	266	13	al	al	PROPN
dpc-3935	266	14	.	.	PUNCT
dpc-3935	267	1	expanding	expand	VERB
dpc-3935	267	2	the	the	DET
dpc-3935	267	3	phenotype	phenotype	NOUN
dpc-3935	267	4	of	of	ADP
dpc-3935	267	5	e318k	e318k	PROPN
dpc-3935	267	6	(	(	PUNCT
dpc-3935	267	7	c.952	c.952	NOUN
dpc-3935	267	8	g	g	PROPN
dpc-3935	267	9	>	>	X
dpc-3935	267	10	a	a	PRON
dpc-3935	267	11	)	)	PUNCT
dpc-3935	267	12	mitf	mitf	NOUN
dpc-3935	267	13	germline	germline	NOUN
dpc-3935	267	14	mutation	mutation	NOUN
dpc-3935	267	15	carriers	carrier	NOUN
dpc-3935	267	16	:	:	PUNCT
dpc-3935	267	17	case	case	NOUN
dpc-3935	267	18	series	series	NOUN
dpc-3935	267	19	and	and	CCONJ
dpc-3935	267	20	review	review	NOUN
dpc-3935	267	21	of	of	ADP
dpc-3935	267	22	the	the	DET
dpc-3935	267	23	literature	literature	NOUN
dpc-3935	267	24	.	.	PUNCT
dpc-3935	268	1	hered	here	VERB
dpc-3935	268	2	cancer	cancer	NOUN
dpc-3935	268	3	clin	clin	PROPN
dpc-3935	268	4	pract	pract	PROPN
dpc-3935	268	5	2021	2021	NUM
dpc-3935	268	6	,	,	PUNCT
dpc-3935	268	7	19(1):32	19(1):32	PROPN
dpc-3935	268	8	.	.	PUNCT
dpc-3935	269	1	pmid	pmid	NOUN
dpc-3935	269	2	:	:	PUNCT
dpc-3935	269	3	 	 	SPACE
dpc-3935	269	4	34289891	34289891	NUM
dpc-3935	269	5	pmcid	pmcid	NOUN
dpc-3935	269	6	:	:	PUNCT
dpc-3935	269	7	 	 	SPACE
dpc-3935	269	8	pmc8293540	pmc8293540	NOUN
dpc-3935	269	9	.	.	PUNCT
dpc-3935	270	1	26	26	NUM
dpc-3935	270	2	.	.	PUNCT
dpc-3935	270	3	sturm	sturm	PROPN
dpc-3935	270	4	ra	ra	PROPN
dpc-3935	270	5	,	,	PUNCT
dpc-3935	270	6	fox	fox	PROPN
dpc-3935	270	7	c	c	AUX
dpc-3935	270	8	,	,	PUNCT
dpc-3935	270	9	mcclenahan	mcclenahan	NOUN
dpc-3935	270	10	p	p	PROPN
dpc-3935	270	11	,	,	PUNCT
dpc-3935	270	12	et	et	PROPN
dpc-3935	270	13	al	al	PROPN
dpc-3935	270	14	.	.	PUNCT
dpc-3935	271	1	phenotypic	phenotypic	ADJ
dpc-3935	271	2	characterization	characterization	NOUN
dpc-3935	271	3	of	of	ADP
dpc-3935	271	4	nevus	nevus	ADJ
dpc-3935	271	5	and	and	CCONJ
dpc-3935	271	6	tumor	tumor	NOUN
dpc-3935	271	7	patterns	pattern	NOUN
dpc-3935	271	8	in	in	ADP
dpc-3935	271	9	mitf	mitf	ADJ
dpc-3935	271	10	e318k	e318k	PROPN
dpc-3935	271	11	mutation	mutation	NOUN
dpc-3935	271	12	carrier	carrier	NOUN
dpc-3935	271	13	melanoma	melanoma	NOUN
dpc-3935	271	14	patients	patient	NOUN
dpc-3935	271	15	.	.	PUNCT
dpc-3935	272	1	j	j	PROPN
dpc-3935	272	2	invest	invest	VERB
dpc-3935	272	3	dermatol	dermatol	NOUN
dpc-3935	272	4	2014	2014	NUM
dpc-3935	272	5	,	,	PUNCT
dpc-3935	272	6	134(1	134(1	NUM
dpc-3935	272	7	):	):	PUNCT
dpc-3935	272	8	141	141	NUM
dpc-3935	272	9	-	-	SYM
dpc-3935	272	10	149	149	NUM
dpc-3935	272	11	.	.	PUNCT
dpc-3935	273	1	pmid	pmid	NOUN
dpc-3935	273	2	:	:	PUNCT
dpc-3935	273	3	 	 	SPACE
dpc-3935	273	4	23774529	23774529	NUM
dpc-3935	273	5	.	.	PUNCT
dpc-3935	274	1	27	27	NUM
dpc-3935	274	2	.	.	X
dpc-3935	274	3	ghiorzo	ghiorzo	PROPN
dpc-3935	274	4	p	p	NOUN
dpc-3935	274	5	,	,	PUNCT
dpc-3935	274	6	pastorino	pastorino	PROPN
dpc-3935	274	7	l	l	PROPN
dpc-3935	274	8	,	,	PUNCT
dpc-3935	274	9	queirolo	queirolo	PROPN
dpc-3935	274	10	p	p	X
dpc-3935	274	11	,	,	PUNCT
dpc-3935	274	12	et	et	PROPN
dpc-3935	274	13	al	al	PROPN
dpc-3935	274	14	.	.	PUNCT
dpc-3935	275	1	prevalence	prevalence	NOUN
dpc-3935	275	2	of	of	ADP
dpc-3935	275	3	the	the	DET
dpc-3935	275	4	e318k	e318k	PROPN
dpc-3935	275	5	mitf	mitf	NOUN
dpc-3935	275	6	germline	germline	NOUN
dpc-3935	275	7	mutation	mutation	NOUN
dpc-3935	275	8	in	in	ADP
dpc-3935	275	9	italian	italian	ADJ
dpc-3935	275	10	melanoma	melanoma	NOUN
dpc-3935	275	11	patients	patient	NOUN
dpc-3935	275	12	:	:	PUNCT
dpc-3935	275	13	associations	association	NOUN
dpc-3935	275	14	with	with	ADP
dpc-3935	275	15	histological	histological	ADJ
dpc-3935	275	16	subtypes	subtype	NOUN
dpc-3935	275	17	and	and	CCONJ
dpc-3935	275	18	family	family	NOUN
dpc-3935	275	19	cancer	cancer	NOUN
dpc-3935	275	20	history	history	NOUN
dpc-3935	275	21	.	.	PUNCT
dpc-3935	276	1	pigment	pigment	ADJ
dpc-3935	276	2	cell	cell	NOUN
dpc-3935	276	3	melanoma	melanoma	NOUN
dpc-3935	276	4	res	re	NOUN
dpc-3935	276	5	2013	2013	NUM
dpc-3935	276	6	,	,	PUNCT
dpc-3935	276	7	26(2):259	26(2):259	NUM
dpc-3935	276	8	-	-	SYM
dpc-3935	276	9	262	262	NUM
dpc-3935	276	10	.	.	PUNCT
dpc-3935	277	1	pmid	pmid	NOUN
dpc-3935	277	2	:	:	PUNCT
dpc-3935	277	3	  	  	SPACE
dpc-3935	277	4	23167872	23167872	NUM
dpc-3935	277	5	.	.	PUNCT
dpc-3935	278	1	28	28	NUM
dpc-3935	278	2	.	.	PUNCT
dpc-3935	279	1	gupta	gupta	PROPN
dpc-3935	279	2	s	s	PART
dpc-3935	279	3	,	,	PUNCT
dpc-3935	279	4	erickson	erickson	PROPN
dpc-3935	279	5	la	la	PROPN
dpc-3935	279	6	,	,	PUNCT
dpc-3935	279	7	lohse	lohse	PROPN
dpc-3935	279	8	cm	cm	PROPN
dpc-3935	279	9	,	,	PUNCT
dpc-3935	279	10	et	et	PROPN
dpc-3935	279	11	al	al	PROPN
dpc-3935	279	12	.	.	PROPN
dpc-3935	279	13	assessment	assessment	NOUN
dpc-3935	279	14	of	of	ADP
dpc-3935	279	15	risk	risk	NOUN
dpc-3935	279	16	of	of	ADP
dpc-3935	279	17	hereditary	hereditary	ADJ
dpc-3935	279	18	predisposition	predisposition	NOUN
dpc-3935	279	19	in	in	ADP
dpc-3935	279	20	patients	patient	NOUN
dpc-3935	279	21	with	with	ADP
dpc-3935	279	22	melanoma	melanoma	NOUN
dpc-3935	279	23	and/or	and/or	CCONJ
dpc-3935	279	24	mesothelioma	mesothelioma	NOUN
dpc-3935	279	25	and	and	CCONJ
dpc-3935	279	26	renal	renal	ADJ
dpc-3935	279	27	neoplasia	neoplasia	NOUN
dpc-3935	279	28	.	.	PUNCT
dpc-3935	280	1	jama	jama	PROPN
dpc-3935	280	2	network	network	PROPN
dpc-3935	280	3	open	open	ADJ
dpc-3935	280	4	2021	2021	NUM
dpc-3935	280	5	,	,	PUNCT
dpc-3935	280	6	4(11):e2132615	4(11):e2132615	NUM
dpc-3935	280	7	.	.	PUNCT
dpc-3935	281	1	pmid	pmid	NOUN
dpc-3935	281	2	:	:	PUNCT
dpc-3935	281	3	 	 	SPACE
dpc-3935	281	4	34767027	34767027	NUM
dpc-3935	281	5	.	.	PUNCT
dpc-3935	282	1	29	29	NUM
dpc-3935	282	2	.	.	PUNCT
dpc-3935	283	1	goggins	goggin	NOUN
dpc-3935	283	2	m	m	PROPN
dpc-3935	283	3	,	,	PUNCT
dpc-3935	283	4	overbeek	overbeek	PROPN
dpc-3935	283	5	ka	ka	PROPN
dpc-3935	283	6	,	,	PUNCT
dpc-3935	283	7	brand	brand	NOUN
dpc-3935	283	8	r	r	NOUN
dpc-3935	283	9	,	,	PUNCT
dpc-3935	283	10	et	et	PROPN
dpc-3935	283	11	al	al	PROPN
dpc-3935	283	12	.	.	PUNCT
dpc-3935	283	13	management	management	NOUN
dpc-3935	283	14	of	of	ADP
dpc-3935	283	15	patients	patient	NOUN
dpc-3935	283	16	with	with	ADP
dpc-3935	283	17	increased	increase	VERB
dpc-3935	283	18	risk	risk	NOUN
dpc-3935	283	19	for	for	ADP
dpc-3935	283	20	familial	familial	ADJ
dpc-3935	283	21	pancreatic	pancreatic	ADJ
dpc-3935	283	22	cancer	cancer	NOUN
dpc-3935	283	23	:	:	PUNCT
dpc-3935	283	24	updated	update	VERB
dpc-3935	283	25	recommendations	recommendation	NOUN
dpc-3935	283	26	from	from	ADP
dpc-3935	283	27	the	the	DET
dpc-3935	283	28	international	international	ADJ
dpc-3935	283	29	cancer	cancer	NOUN
dpc-3935	283	30	of	of	ADP
dpc-3935	283	31	the	the	DET
dpc-3935	283	32	pancreas	pancreas	NOUN
dpc-3935	283	33	screening	screen	VERB
dpc-3935	283	34	(	(	PUNCT
dpc-3935	283	35	caps	cap	NOUN
dpc-3935	283	36	)	)	PUNCT
dpc-3935	283	37	consortium	consortium	NOUN
dpc-3935	283	38	.	.	PUNCT
dpc-3935	284	1	gut	gut	PROPN
dpc-3935	284	2	2020	2020	NUM
dpc-3935	284	3	,	,	PUNCT
dpc-3935	284	4	69(1):7	69(1):7	PROPN
dpc-3935	284	5	-	-	SYM
dpc-3935	284	6	17	17	NUM
dpc-3935	284	7	.	.	PUNCT
dpc-3935	285	1	pmid	pmid	NOUN
dpc-3935	285	2	:	:	PUNCT
dpc-3935	285	3	  	  	SPACE
dpc-3935	285	4	31672839	31672839	NUM
dpc-3935	285	5	pmcid	pmcid	NOUN
dpc-3935	285	6	:	:	PUNCT
dpc-3935	285	7	 	 	SPACE
dpc-3935	285	8	pmc7295005	pmc7295005	ADJ
dpc-3935	285	9	.	.	PUNCT
dpc-3935	286	1	30	30	X
dpc-3935	286	2	.	.	PUNCT
dpc-3935	287	1	capurso	capurso	PROPN
dpc-3935	287	2	g	g	PROPN
dpc-3935	287	3	,	,	PUNCT
dpc-3935	287	4	paiella	paiella	PROPN
dpc-3935	287	5	s	s	PROPN
dpc-3935	287	6	,	,	PUNCT
dpc-3935	287	7	carrara	carrara	PROPN
dpc-3935	287	8	s	s	PROPN
dpc-3935	287	9	,	,	PUNCT
dpc-3935	287	10	et	et	PROPN
dpc-3935	287	11	al	al	PROPN
dpc-3935	287	12	.	.	PUNCT
dpc-3935	288	1	italian	italian	ADJ
dpc-3935	288	2	registry	registry	NOUN
dpc-3935	288	3	of	of	ADP
dpc-3935	288	4	families	family	NOUN
dpc-3935	288	5	at	at	ADP
dpc-3935	288	6	risk	risk	NOUN
dpc-3935	288	7	of	of	ADP
dpc-3935	288	8	pancreatic	pancreatic	ADJ
dpc-3935	288	9	cancer	cancer	NOUN
dpc-3935	288	10	:	:	PUNCT
dpc-3935	288	11	aisp	aisp	NOUN
dpc-3935	288	12	familial	familial	ADJ
dpc-3935	288	13	pancreatic	pancreatic	ADJ
dpc-3935	288	14	cancer	cancer	NOUN
dpc-3935	288	15	study	study	NOUN
dpc-3935	288	16	group	group	NOUN
dpc-3935	288	17	.	.	PUNCT
dpc-3935	289	1	dig	dig	VERB
dpc-3935	289	2	liver	liver	NOUN
dpc-3935	289	3	dis	dis	PROPN
dpc-3935	289	4	2020	2020	NUM
dpc-3935	289	5	,	,	PUNCT
dpc-3935	289	6	52(10):1126	52(10):1126	NUM
dpc-3935	289	7	-	-	SYM
dpc-3935	289	8	1130	1130	NUM
dpc-3935	289	9	.	.	PUNCT
dpc-3935	290	1	pmid	pmid	NOUN
dpc-3935	290	2	:	:	PUNCT
dpc-3935	290	3	  	  	SPACE
dpc-3935	290	4	32819857	32819857	NUM
dpc-3935	290	5	.	.	PUNCT
dpc-3935	291	1	3	3	X
dpc-3935	291	2	.	.	X
dpc-3935	291	3	goldstein	goldstein	PROPN
dpc-3935	291	4	am	am	PROPN
dpc-3935	291	5	,	,	PUNCT
dpc-3935	291	6	chan	chan	PROPN
dpc-3935	291	7	m	m	PROPN
dpc-3935	291	8	,	,	PUNCT
dpc-3935	291	9	harland	harland	PROPN
dpc-3935	291	10	m	m	PROPN
dpc-3935	291	11	,	,	PUNCT
dpc-3935	291	12	et	et	PROPN
dpc-3935	291	13	al	al	PROPN
dpc-3935	291	14	.	.	PROPN
dpc-3935	291	15	high	high	ADJ
dpc-3935	291	16	-	-	PUNCT
dpc-3935	291	17	risk	risk	NOUN
dpc-3935	291	18	melanoma	melanoma	NOUN
dpc-3935	291	19	susceptibility	susceptibility	NOUN
dpc-3935	291	20	genes	gene	NOUN
dpc-3935	291	21	and	and	CCONJ
dpc-3935	291	22	pancreatic	pancreatic	ADJ
dpc-3935	291	23	cancer	cancer	NOUN
dpc-3935	291	24	,	,	PUNCT
dpc-3935	291	25	neural	neural	ADJ
dpc-3935	291	26	system	system	NOUN
dpc-3935	291	27	tumors	tumor	NOUN
dpc-3935	291	28	,	,	PUNCT
dpc-3935	291	29	and	and	CCONJ
dpc-3935	291	30	uveal	uveal	ADJ
dpc-3935	291	31	melanoma	melanoma	NOUN
dpc-3935	291	32	across	across	ADP
dpc-3935	291	33	genomel	genomel	NOUN
dpc-3935	291	34	.	.	PUNCT
dpc-3935	292	1	cancer	cancer	NOUN
dpc-3935	292	2	res	re	NOUN
dpc-3935	292	3	2006	2006	NUM
dpc-3935	292	4	,	,	PUNCT
dpc-3935	292	5	66(20	66(20	NUM
dpc-3935	292	6	):	):	PUNCT
dpc-3935	292	7	9818	9818	NUM
dpc-3935	292	8	-	-	SYM
dpc-3935	292	9	9828	9828	NUM
dpc-3935	292	10	.	.	PUNCT
dpc-3935	293	1	pmid	pmid	NOUN
dpc-3935	293	2	:	:	PUNCT
dpc-3935	293	3	 	 	SPACE
dpc-3935	293	4	17047042	17047042	NUM
dpc-3935	293	5	.	.	PUNCT
dpc-3935	294	1	4	4	X
dpc-3935	294	2	.	.	X
dpc-3935	294	3	leachman	leachman	PROPN
dpc-3935	294	4	sa	sa	PROPN
dpc-3935	294	5	,	,	PUNCT
dpc-3935	294	6	carucci	carucci	PROPN
dpc-3935	294	7	j	j	PROPN
dpc-3935	294	8	,	,	PUNCT
dpc-3935	294	9	kohlmann	kohlmann	PROPN
dpc-3935	294	10	w	w	PROPN
dpc-3935	294	11	,	,	PUNCT
dpc-3935	294	12	et	et	PROPN
dpc-3935	294	13	al	al	PROPN
dpc-3935	294	14	.	.	PROPN
dpc-3935	294	15	selection	selection	NOUN
dpc-3935	294	16	criteria	criterion	NOUN
dpc-3935	294	17	for	for	ADP
dpc-3935	294	18	genetic	genetic	ADJ
dpc-3935	294	19	assessment	assessment	NOUN
dpc-3935	294	20	of	of	ADP
dpc-3935	294	21	patients	patient	NOUN
dpc-3935	294	22	with	with	ADP
dpc-3935	294	23	familial	familial	ADJ
dpc-3935	294	24	melanoma	melanoma	NOUN
dpc-3935	294	25	.	.	PUNCT
dpc-3935	295	1	j	j	PROPN
dpc-3935	295	2	am	be	AUX
dpc-3935	295	3	acad	acad	ADJ
dpc-3935	295	4	dermatol	dermatol	NOUN
dpc-3935	295	5	2009	2009	NUM
dpc-3935	295	6	,	,	PUNCT
dpc-3935	295	7	61(4):677	61(4):677	PROPN
dpc-3935	295	8	e671	e671	PROPN
dpc-3935	295	9	-	-	PUNCT
dpc-3935	295	10	614	614	NUM
dpc-3935	295	11	.	.	PUNCT
dpc-3935	296	1	pmid	pmid	NOUN
dpc-3935	296	2	:	:	PUNCT
dpc-3935	296	3	  	  	SPACE
dpc-3935	296	4	19751883	19751883	NUM
dpc-3935	296	5	pmcid	pmcid	NOUN
dpc-3935	296	6	:	:	PUNCT
dpc-3935	296	7	 	 	SPACE
dpc-3935	296	8	pmc3307795	pmc3307795	NOUN
dpc-3935	296	9	.	.	PUNCT
dpc-3935	297	1	5	5	X
dpc-3935	297	2	.	.	X
dpc-3935	297	3	de	de	PROPN
dpc-3935	297	4	snoo	snoo	PROPN
dpc-3935	297	5	fa	fa	PROPN
dpc-3935	297	6	,	,	PUNCT
dpc-3935	297	7	hayward	hayward	PROPN
dpc-3935	297	8	nk	nk	PROPN
dpc-3935	297	9	.	.	PUNCT
dpc-3935	298	1	cutaneous	cutaneous	ADJ
dpc-3935	298	2	melanoma	melanoma	NOUN
dpc-3935	298	3	susceptibility	susceptibility	NOUN
dpc-3935	298	4	and	and	CCONJ
dpc-3935	298	5	progression	progression	NOUN
dpc-3935	298	6	genes	gene	NOUN
dpc-3935	298	7	.	.	PUNCT
dpc-3935	299	1	cancer	cancer	NOUN
dpc-3935	299	2	lett	lett	PROPN
dpc-3935	299	3	2005	2005	NUM
dpc-3935	299	4	,	,	PUNCT
dpc-3935	299	5	230(2):153	230(2):153	NUM
dpc-3935	299	6	-	-	SYM
dpc-3935	299	7	186	186	NUM
dpc-3935	299	8	.	.	PUNCT
dpc-3935	300	1	pmid	pmid	NOUN
dpc-3935	300	2	:	:	PUNCT
dpc-3935	300	3	 	 	SPACE
dpc-3935	300	4	16297704	16297704	NUM
dpc-3935	300	5	.	.	PUNCT
dpc-3935	301	1	6	6	NUM
dpc-3935	301	2	.	.	X
dpc-3935	301	3	bruno	bruno	PROPN
dpc-3935	301	4	w	w	PROPN
dpc-3935	301	5	,	,	PUNCT
dpc-3935	301	6	pastorino	pastorino	PROPN
dpc-3935	301	7	l	l	PROPN
dpc-3935	301	8	,	,	PUNCT
dpc-3935	301	9	ghiorzo	ghiorzo	NOUN
dpc-3935	301	10	p	p	NOUN
dpc-3935	301	11	,	,	PUNCT
dpc-3935	301	12	et	et	PROPN
dpc-3935	301	13	al	al	PROPN
dpc-3935	301	14	.	.	PUNCT
dpc-3935	301	15	multiple	multiple	ADJ
dpc-3935	301	16	primary	primary	ADJ
dpc-3935	301	17	melanomas	melanomas	NOUN
dpc-3935	301	18	(	(	PUNCT
dpc-3935	301	19	mpms	mpm	NOUN
dpc-3935	301	20	)	)	PUNCT
dpc-3935	301	21	and	and	CCONJ
dpc-3935	301	22	criteria	criterion	NOUN
dpc-3935	301	23	for	for	ADP
dpc-3935	301	24	genetic	genetic	ADJ
dpc-3935	301	25	assessment	assessment	NOUN
dpc-3935	301	26	:	:	PUNCT
dpc-3935	301	27	multimel	multimel	PROPN
dpc-3935	301	28	,	,	PUNCT
dpc-3935	301	29	a	a	DET
dpc-3935	301	30	multicenter	multicenter	ADJ
dpc-3935	301	31	study	study	NOUN
dpc-3935	301	32	of	of	ADP
dpc-3935	301	33	the	the	DET
dpc-3935	301	34	italian	italian	ADJ
dpc-3935	301	35	melanoma	melanoma	NOUN
dpc-3935	301	36	intergroup	intergroup	NOUN
dpc-3935	301	37	.	.	PUNCT
dpc-3935	302	1	j	j	PROPN
dpc-3935	302	2	am	be	AUX
dpc-3935	302	3	acad	acad	ADJ
dpc-3935	302	4	dermatol	dermatol	NOUN
dpc-3935	302	5	2016	2016	NUM
dpc-3935	302	6	,	,	PUNCT
dpc-3935	302	7	74(2):325	74(2):325	PROPN
dpc-3935	302	8	-	-	PUNCT
dpc-3935	302	9	332	332	NUM
dpc-3935	302	10	.	.	PUNCT
dpc-3935	303	1	pmid	pmid	NOUN
dpc-3935	303	2	:	:	PUNCT
dpc-3935	303	3	 	 	SPACE
dpc-3935	303	4	26775776	26775776	NUM
dpc-3935	303	5	.	.	PUNCT
dpc-3935	304	1	7	7	X
dpc-3935	304	2	.	.	X
dpc-3935	304	3	siegel	siegel	PROPN
dpc-3935	304	4	rl	rl	PROPN
dpc-3935	304	5	,	,	PUNCT
dpc-3935	304	6	miller	miller	PROPN
dpc-3935	304	7	kd	kd	PROPN
dpc-3935	304	8	,	,	PUNCT
dpc-3935	304	9	wagle	wagle	NOUN
dpc-3935	304	10	ns	ns	ADJ
dpc-3935	304	11	,	,	PUNCT
dpc-3935	304	12	jemal	jemal	ADJ
dpc-3935	304	13	a.	a.	NOUN
dpc-3935	304	14	cancer	cancer	NOUN
dpc-3935	304	15	statistics	statistic	NOUN
dpc-3935	304	16	,	,	PUNCT
dpc-3935	304	17	2023	2023	NUM
dpc-3935	304	18	.	.	PUNCT
dpc-3935	305	1	ca	can	AUX
dpc-3935	305	2	cancer	cancer	PROPN
dpc-3935	305	3	j	j	PROPN
dpc-3935	305	4	clin	clin	PROPN
dpc-3935	305	5	2023	2023	NUM
dpc-3935	305	6	,	,	PUNCT
dpc-3935	305	7	73(1):17	73(1):17	NUM
dpc-3935	305	8	-	-	SYM
dpc-3935	305	9	48	48	NUM
dpc-3935	305	10	.	.	PUNCT
dpc-3935	306	1	pmid	pmid	NOUN
dpc-3935	306	2	:	:	PUNCT
dpc-3935	306	3	 	 	SPACE
dpc-3935	306	4	36633525	36633525	NUM
dpc-3935	306	5	.	.	PUNCT
dpc-3935	307	1	8	8	NUM
dpc-3935	307	2	.	.	X
dpc-3935	307	3	leachman	leachman	PROPN
dpc-3935	307	4	sa	sa	PROPN
dpc-3935	307	5	,	,	PUNCT
dpc-3935	307	6	lucero	lucero	PROPN
dpc-3935	307	7	om	om	PROPN
dpc-3935	307	8	,	,	PUNCT
dpc-3935	307	9	sampson	sampson	PROPN
dpc-3935	307	10	je	je	PROPN
dpc-3935	307	11	,	,	PUNCT
dpc-3935	307	12	et	et	PROPN
dpc-3935	307	13	al	al	PROPN
dpc-3935	307	14	.	.	PUNCT
dpc-3935	307	15	identification	identification	NOUN
dpc-3935	307	16	,	,	PUNCT
dpc-3935	307	17	genetic	genetic	ADJ
dpc-3935	307	18	testing	testing	NOUN
dpc-3935	307	19	,	,	PUNCT
dpc-3935	307	20	and	and	CCONJ
dpc-3935	307	21	management	management	NOUN
dpc-3935	307	22	of	of	ADP
dpc-3935	307	23	hereditary	hereditary	ADJ
dpc-3935	307	24	melanoma	melanoma	NOUN
dpc-3935	307	25	.	.	PUNCT
dpc-3935	308	1	cancer	cancer	NOUN
dpc-3935	308	2	metastasis	metastasis	NOUN
dpc-3935	308	3	rev	rev	VERB
dpc-3935	308	4	2017	2017	NUM
dpc-3935	308	5	,	,	PUNCT
dpc-3935	308	6	36(1):77	36(1):77	NUM
dpc-3935	308	7	-	-	SYM
dpc-3935	308	8	90	90	NUM
dpc-3935	308	9	.	.	PUNCT
dpc-3935	309	1	pmid	pmid	NOUN
dpc-3935	309	2	:	:	PUNCT
dpc-3935	309	3	  	  	SPACE
dpc-3935	309	4	28283772	28283772	NUM
dpc-3935	309	5	pmcid	pmcid	NOUN
dpc-3935	309	6	:	:	PUNCT
dpc-3935	309	7	  	  	SPACE
dpc-3935	309	8	pmc5385190	pmc5385190	NOUN
dpc-3935	309	9	.	.	PUNCT
dpc-3935	310	1	9	9	X
dpc-3935	310	2	.	.	NUM
dpc-3935	310	3	aoude	aoude	NOUN
dpc-3935	310	4	lg	lg	PROPN
dpc-3935	310	5	,	,	PUNCT
dpc-3935	310	6	wadt	wadt	PROPN
dpc-3935	310	7	ka	ka	PROPN
dpc-3935	310	8	,	,	PUNCT
dpc-3935	310	9	pritchard	pritchard	PROPN
dpc-3935	310	10	al	al	PROPN
dpc-3935	310	11	,	,	PUNCT
dpc-3935	310	12	hayward	hayward	PROPN
dpc-3935	310	13	nk	nk	PROPN
dpc-3935	310	14	.	.	PUNCT
dpc-3935	311	1	genetics	genetic	NOUN
dpc-3935	311	2	of	of	ADP
dpc-3935	311	3	familial	familial	ADJ
dpc-3935	311	4	melanoma	melanoma	NOUN
dpc-3935	311	5	:	:	PUNCT
dpc-3935	311	6	20	20	NUM
dpc-3935	311	7	years	year	NOUN
dpc-3935	311	8	after	after	ADP
dpc-3935	311	9	cdkn2a	cdkn2a	PROPN
dpc-3935	311	10	.	.	PUNCT
dpc-3935	312	1	pigment	pigment	NOUN
dpc-3935	312	2	cell	cell	NOUN
dpc-3935	312	3	melanoma	melanoma	NOUN
dpc-3935	312	4	res	re	NOUN
dpc-3935	312	5	2015	2015	NUM
dpc-3935	312	6	,	,	PUNCT
dpc-3935	312	7	28(2):148	28(2):148	NUM
dpc-3935	312	8	-	-	SYM
dpc-3935	312	9	160	160	NUM
dpc-3935	312	10	.	.	PUNCT
dpc-3935	313	1	pmid	pmid	NOUN
dpc-3935	313	2	:	:	PUNCT
dpc-3935	313	3	 	 	SPACE
dpc-3935	313	4	25431349	25431349	NUM
dpc-3935	313	5	.	.	PUNCT
dpc-3935	314	1	10	10	NUM
dpc-3935	314	2	.	.	X
dpc-3935	315	1	goldstein	goldstein	PROPN
dpc-3935	315	2	am	am	PROPN
dpc-3935	315	3	,	,	PUNCT
dpc-3935	315	4	chan	chan	PROPN
dpc-3935	315	5	m	m	PROPN
dpc-3935	315	6	,	,	PUNCT
dpc-3935	315	7	harland	harland	PROPN
dpc-3935	315	8	m	m	PROPN
dpc-3935	315	9	,	,	PUNCT
dpc-3935	315	10	et	et	PROPN
dpc-3935	315	11	al	al	PROPN
dpc-3935	315	12	.	.	PROPN
dpc-3935	315	13	features	feature	NOUN
dpc-3935	315	14	associated	associate	VERB
dpc-3935	315	15	with	with	ADP
dpc-3935	315	16	germline	germline	NOUN
dpc-3935	315	17	cdkn2a	cdkn2a	PROPN
dpc-3935	315	18	mutations	mutation	NOUN
dpc-3935	315	19	:	:	PUNCT
dpc-3935	315	20	a	a	DET
dpc-3935	315	21	genomel	genomel	NOUN
dpc-3935	315	22	study	study	NOUN
dpc-3935	315	23	of	of	ADP
dpc-3935	315	24	melanoma	melanoma	NOUN
dpc-3935	315	25	-	-	PUNCT
dpc-3935	315	26	prone	prone	ADJ
dpc-3935	315	27	families	family	NOUN
dpc-3935	315	28	from	from	ADP
dpc-3935	315	29	three	three	NUM
dpc-3935	315	30	continents	continent	NOUN
dpc-3935	315	31	.	.	PUNCT
dpc-3935	316	1	journal	journal	PROPN
dpc-3935	316	2	of	of	ADP
dpc-3935	316	3	medical	medical	ADJ
dpc-3935	316	4	genetics	genetic	NOUN
dpc-3935	316	5	2007	2007	NUM
dpc-3935	316	6	,	,	PUNCT
dpc-3935	316	7	44(2):99	44(2):99	PROPN
dpc-3935	316	8	-	-	PUNCT
dpc-3935	316	9	106	106	NUM
dpc-3935	316	10	.	.	PUNCT
dpc-3935	317	1	pmid	pmid	NOUN
dpc-3935	317	2	:	:	PUNCT
dpc-3935	317	3	 	 	SPACE
dpc-3935	317	4	16905682	16905682	NUM
dpc-3935	317	5	pmcid	pmcid	NOUN
dpc-3935	317	6	:	:	PUNCT
dpc-3935	317	7	  	  	SPACE
dpc-3935	317	8	pmc2598064	pmc2598064	NOUN
dpc-3935	317	9	.	.	PUNCT
dpc-3935	318	1	11	11	NUM
dpc-3935	318	2	.	.	X
dpc-3935	318	3	pedace	pedace	NOUN
dpc-3935	318	4	l	l	NOUN
dpc-3935	318	5	,	,	PUNCT
dpc-3935	318	6	de	de	ADP
dpc-3935	318	7	simone	simone	PROPN
dpc-3935	318	8	p	p	NOUN
dpc-3935	318	9	,	,	PUNCT
dpc-3935	318	10	castori	castori	PROPN
dpc-3935	318	11	m	m	PROPN
dpc-3935	318	12	,	,	PUNCT
dpc-3935	318	13	et	et	PROPN
dpc-3935	318	14	al	al	PROPN
dpc-3935	318	15	.	.	PUNCT
dpc-3935	319	1	clinical	clinical	ADJ
dpc-3935	319	2	features	feature	NOUN
dpc-3935	319	3	predicting	predict	VERB
dpc-3935	319	4	identification	identification	NOUN
dpc-3935	319	5	of	of	ADP
dpc-3935	319	6	cdkn2a	cdkn2a	ADJ
dpc-3935	319	7	mutations	mutation	NOUN
dpc-3935	319	8	in	in	ADP
dpc-3935	319	9	italian	italian	ADJ
dpc-3935	319	10	patients	patient	NOUN
dpc-3935	319	11	with	with	ADP
dpc-3935	319	12	familial	familial	ADJ
dpc-3935	319	13	cutaneous	cutaneous	ADJ
dpc-3935	319	14	melanoma	melanoma	NOUN
dpc-3935	319	15	.	.	PUNCT
dpc-3935	320	1	cancer	cancer	NOUN
dpc-3935	320	2	epidemiol	epidemiol	PROPN
dpc-3935	320	3	2011	2011	NUM
dpc-3935	320	4	,	,	PUNCT
dpc-3935	320	5	35(6):e116	35(6):e116	NUM
dpc-3935	320	6	-	-	SYM
dpc-3935	320	7	120	120	NUM
dpc-3935	320	8	.	.	PUNCT
dpc-3935	321	1	pmid	pmid	NOUN
dpc-3935	321	2	:	:	PUNCT
dpc-3935	321	3	 	 	SPACE
dpc-3935	321	4	21893440	21893440	NUM
dpc-3935	321	5	.	.	PUNCT
dpc-3935	322	1	12	12	NUM
dpc-3935	322	2	.	.	PUNCT
dpc-3935	323	1	read	read	PROPN
dpc-3935	323	2	j	j	PROPN
dpc-3935	323	3	,	,	PUNCT
dpc-3935	323	4	wadt	wadt	PROPN
dpc-3935	323	5	ka	ka	PROPN
dpc-3935	323	6	,	,	PUNCT
dpc-3935	323	7	hayward	hayward	PROPN
dpc-3935	323	8	nk	nk	PROPN
dpc-3935	323	9	.	.	PUNCT
dpc-3935	324	1	melanoma	melanoma	PROPN
dpc-3935	324	2	genetics	genetics	PROPN
dpc-3935	324	3	.	.	PUNCT
dpc-3935	325	1	journal	journal	PROPN
dpc-3935	325	2	of	of	ADP
dpc-3935	325	3	medical	medical	ADJ
dpc-3935	325	4	genetics	genetic	NOUN
dpc-3935	325	5	2016	2016	NUM
dpc-3935	325	6	,	,	PUNCT
dpc-3935	325	7	53(1):1	53(1):1	PROPN
dpc-3935	325	8	-	-	PUNCT
dpc-3935	325	9	14	14	NUM
dpc-3935	325	10	.	.	PUNCT
dpc-3935	326	1	pmid	pmid	NOUN
dpc-3935	326	2	:	:	PUNCT
dpc-3935	326	3	 	 	SPACE
dpc-3935	326	4	26337759	26337759	NUM
dpc-3935	326	5	.	.	PUNCT
dpc-3935	327	1	13	13	NUM
dpc-3935	327	2	.	.	PUNCT
dpc-3935	328	1	bruno	bruno	PROPN
dpc-3935	328	2	w	w	PROPN
dpc-3935	328	3	,	,	PUNCT
dpc-3935	328	4	ghiorzo	ghiorzo	NOUN
dpc-3935	328	5	p	p	NOUN
dpc-3935	328	6	,	,	PUNCT
dpc-3935	328	7	battistuzzi	battistuzzi	NOUN
dpc-3935	328	8	l	l	PROPN
dpc-3935	328	9	,	,	PUNCT
dpc-3935	328	10	et	et	PROPN
dpc-3935	328	11	al	al	PROPN
dpc-3935	328	12	.	.	PROPN
dpc-3935	329	1	clinical	clinical	ADJ
dpc-3935	329	2	genetic	genetic	ADJ
dpc-3935	329	3	testing	testing	NOUN
dpc-3935	329	4	for	for	ADP
dpc-3935	329	5	familial	familial	ADJ
dpc-3935	329	6	melanoma	melanoma	NOUN
dpc-3935	329	7	in	in	ADP
dpc-3935	329	8	italy	italy	PROPN
dpc-3935	329	9	:	:	PUNCT
dpc-3935	329	10	a	a	DET
dpc-3935	329	11	cooperative	cooperative	ADJ
dpc-3935	329	12	study	study	NOUN
dpc-3935	329	13	.	.	PUNCT
dpc-3935	330	1	j	j	PROPN
dpc-3935	330	2	am	be	AUX
dpc-3935	330	3	acad	acad	ADJ
dpc-3935	330	4	dermatol	dermatol	NOUN
dpc-3935	330	5	2009	2009	NUM
dpc-3935	330	6	,	,	PUNCT
dpc-3935	330	7	61(5):775	61(5):775	PROPN
dpc-3935	330	8	-	-	PUNCT
dpc-3935	330	9	782	782	NUM
dpc-3935	330	10	.	.	PUNCT
dpc-3935	331	1	pmid	pmid	NOUN
dpc-3935	331	2	:	:	PUNCT
dpc-3935	331	3	 	 	SPACE
dpc-3935	331	4	19500876	19500876	NUM
dpc-3935	331	5	.	.	PUNCT
dpc-3935	332	1	14	14	NUM
dpc-3935	332	2	.	.	PUNCT
dpc-3935	333	1	bruno	bruno	PROPN
dpc-3935	333	2	w	w	PROPN
dpc-3935	333	3	,	,	PUNCT
dpc-3935	333	4	dalmasso	dalmasso	ADJ
dpc-3935	333	5	b	b	NOUN
dpc-3935	333	6	,	,	PUNCT
dpc-3935	333	7	barile	barile	PROPN
dpc-3935	333	8	m	m	PROPN
dpc-3935	333	9	,	,	PUNCT
dpc-3935	333	10	et	et	PROPN
dpc-3935	333	11	al	al	PROPN
dpc-3935	333	12	.	.	PUNCT
dpc-3935	333	13	predictors	predictor	NOUN
dpc-3935	333	14	of	of	ADP
dpc-3935	333	15	germline	germline	NOUN
dpc-3935	333	16	status	status	NOUN
dpc-3935	333	17	for	for	ADP
dpc-3935	333	18	hereditary	hereditary	ADJ
dpc-3935	333	19	melanoma	melanoma	NOUN
dpc-3935	333	20	:	:	PUNCT
dpc-3935	333	21	5	5	NUM
dpc-3935	333	22	years	year	NOUN
dpc-3935	333	23	of	of	ADP
dpc-3935	333	24	multi	multi	ADJ
dpc-3935	333	25	-	-	ADJ
dpc-3935	333	26	gene	gene	ADJ
dpc-3935	333	27	panel	panel	NOUN
dpc-3935	333	28	testing	testing	NOUN
dpc-3935	333	29	within	within	ADP
dpc-3935	333	30	the	the	DET
dpc-3935	333	31	italian	italian	ADJ
dpc-3935	333	32	melanoma	melanoma	NOUN
dpc-3935	333	33	intergroup	intergroup	NOUN
dpc-3935	333	34	.	.	PUNCT
dpc-3935	334	1	esmo	esmo	NOUN
dpc-3935	334	2	open	open	ADJ
dpc-3935	334	3	2022	2022	NUM
dpc-3935	334	4	,	,	PUNCT
dpc-3935	334	5	7(4):100525	7(4):100525	PROPN
dpc-3935	334	6	.	.	PUNCT
dpc-3935	335	1	pmid	pmid	NOUN
dpc-3935	335	2	:	:	PUNCT
dpc-3935	335	3	 	 	SPACE
dpc-3935	335	4	35777164	35777164	NUM
dpc-3935	335	5	pmcid	pmcid	NOUN
dpc-3935	335	6	:	:	PUNCT
dpc-3935	335	7	 	 	SPACE
dpc-3935	335	8	pmc9434136	pmc9434136	NOUN
dpc-3935	335	9	.	.	PUNCT
dpc-3935	336	1	15	15	X
dpc-3935	336	2	.	.	PUNCT
dpc-3935	336	3	klatte	klatte	PROPN
dpc-3935	336	4	dcf	dcf	PROPN
dpc-3935	336	5	,	,	PUNCT
dpc-3935	336	6	boekestijn	boekestijn	PROPN
dpc-3935	336	7	b	b	NUM
dpc-3935	336	8	,	,	PUNCT
dpc-3935	336	9	onnekink	onnekink	PROPN
dpc-3935	336	10	am	am	PROPN
dpc-3935	336	11	,	,	PUNCT
dpc-3935	336	12	et	et	PROPN
dpc-3935	336	13	al	al	PROPN
dpc-3935	336	14	.	.	PROPN
dpc-3935	336	15	surveillance	surveillance	NOUN
dpc-3935	336	16	for	for	ADP
dpc-3935	336	17	pancreatic	pancreatic	ADJ
dpc-3935	336	18	cancer	cancer	NOUN
dpc-3935	336	19	in	in	ADP
dpc-3935	336	20	high	high	ADJ
dpc-3935	336	21	-	-	PUNCT
dpc-3935	336	22	risk	risk	NOUN
dpc-3935	336	23	individuals	individual	NOUN
dpc-3935	336	24	leads	lead	VERB
dpc-3935	336	25	to	to	ADP
dpc-3935	336	26	improved	improved	ADJ
dpc-3935	336	27	outcomes	outcome	NOUN
dpc-3935	336	28	:	:	PUNCT
dpc-3935	336	29	a	a	DET
dpc-3935	336	30	propensity	propensity	NOUN
dpc-3935	336	31	score	score	NOUN
dpc-3935	336	32	-	-	PUNCT
dpc-3935	336	33	matched	match	VERB
dpc-3935	336	34	analysis	analysis	NOUN
dpc-3935	336	35	.	.	PUNCT
dpc-3935	337	1	gastroenterology	gastroenterology	NOUN
dpc-3935	337	2	2023	2023	NUM
dpc-3935	337	3	,	,	PUNCT
dpc-3935	337	4	164(7):1223	164(7):1223	PROPN
dpc-3935	337	5	-	-	PUNCT
dpc-3935	337	6	1231	1231	NUM
dpc-3935	337	7	e1224	e1224	PROPN
dpc-3935	337	8	.	.	PUNCT
dpc-3935	338	1	pmid	pmid	NOUN
dpc-3935	338	2	:	:	PUNCT
dpc-3935	338	3	 	 	SPACE
dpc-3935	338	4	36889551	36889551	NUM
dpc-3935	338	5	.	.	PUNCT
dpc-3935	339	1	16	16	NUM
dpc-3935	339	2	.	.	PUNCT
dpc-3935	339	3	klatte	klatte	PROPN
dpc-3935	339	4	dcf	dcf	PROPN
dpc-3935	339	5	,	,	PUNCT
dpc-3935	339	6	boekestijn	boekestijn	PROPN
dpc-3935	339	7	b	b	PROPN
dpc-3935	339	8	,	,	PUNCT
dpc-3935	339	9	wasser	wasser	PROPN
dpc-3935	339	10	m	m	PROPN
dpc-3935	339	11	,	,	PUNCT
dpc-3935	339	12	et	et	PROPN
dpc-3935	339	13	al	al	PROPN
dpc-3935	339	14	.	.	PROPN
dpc-3935	339	15	pancreatic	pancreatic	ADJ
dpc-3935	339	16	cancer	cancer	NOUN
dpc-3935	339	17	surveillance	surveillance	NOUN
dpc-3935	339	18	in	in	ADP
dpc-3935	339	19	carriers	carrier	NOUN
dpc-3935	339	20	of	of	ADP
dpc-3935	339	21	a	a	DET
dpc-3935	339	22	germline	germline	NOUN
dpc-3935	339	23	cdkn2a	cdkn2a	VERB
dpc-3935	339	24	pathogenic	pathogenic	ADJ
dpc-3935	339	25	variant	variant	NOUN
dpc-3935	339	26	:	:	PUNCT
dpc-3935	339	27	yield	yield	NOUN
dpc-3935	339	28	and	and	CCONJ
dpc-3935	339	29	outcomes	outcome	NOUN
dpc-3935	339	30	of	of	ADP
dpc-3935	339	31	a	a	DET
dpc-3935	339	32	20	20	NUM
dpc-3935	339	33	-	-	PUNCT
dpc-3935	339	34	year	year	NOUN
dpc-3935	339	35	prospective	prospective	ADJ
dpc-3935	339	36	follow	follow	NOUN
dpc-3935	339	37	-	-	PUNCT
dpc-3935	339	38	up	up	NOUN
dpc-3935	339	39	.	.	PUNCT
dpc-3935	340	1	j	j	PROPN
dpc-3935	340	2	 	 	SPACE
dpc-3935	340	3	clin	clin	PROPN
dpc-3935	340	4	oncol	oncol	PROPN
dpc-3935	340	5	2022	2022	NUM
dpc-3935	340	6	,	,	PUNCT
dpc-3935	340	7	40(28):3267	40(28):3267	NUM
dpc-3935	340	8	-	-	SYM
dpc-3935	340	9	3277	3277	NUM
dpc-3935	340	10	.	.	PUNCT
dpc-3935	341	1	pmid	pmid	NOUN
dpc-3935	341	2	:	:	PUNCT
dpc-3935	341	3	 	 	SPACE
dpc-3935	341	4	35658523	35658523	NUM
dpc-3935	341	5	.	.	PUNCT
dpc-3935	342	1	17	17	NUM
dpc-3935	342	2	.	.	X
dpc-3935	342	3	pastorino	pastorino	PROPN
dpc-3935	342	4	l	l	PROPN
dpc-3935	342	5	,	,	PUNCT
dpc-3935	342	6	andreotti	andreotti	PROPN
dpc-3935	342	7	v	v	ADP
dpc-3935	342	8	,	,	PUNCT
dpc-3935	342	9	dalmasso	dalmasso	ADJ
dpc-3935	342	10	b	b	NOUN
dpc-3935	342	11	,	,	PUNCT
dpc-3935	342	12	et	et	PROPN
dpc-3935	342	13	al	al	PROPN
dpc-3935	342	14	.	.	PUNCT
dpc-3935	343	1	insights	insight	NOUN
dpc-3935	343	2	into	into	ADP
dpc-3935	343	3	genetic	genetic	ADJ
dpc-3935	343	4	susceptibility	susceptibility	NOUN
dpc-3935	343	5	to	to	PART
dpc-3935	343	6	melanoma	melanoma	VERB
dpc-3935	343	7	by	by	ADP
dpc-3935	343	8	gene	gene	NOUN
dpc-3935	343	9	panel	panel	NOUN
dpc-3935	343	10	testing	testing	NOUN
dpc-3935	343	11	:	:	PUNCT
dpc-3935	343	12	potential	potential	ADJ