id	sid	tid	token	lemma	pos
dpc-4237	1	1	dermatology	dermatology	NOUN
dpc-4237	1	2	:	:	PUNCT
dpc-4237	1	3	practical	practical	ADJ
dpc-4237	1	4	and	and	CCONJ
dpc-4237	1	5	conceptual	conceptual	ADJ
dpc-4237	1	6	original	original	ADJ
dpc-4237	1	7	article	article	NOUN
dpc-4237	1	8	|	|	ADV
dpc-4237	1	9	dermatol	dermatol	ADJ
dpc-4237	1	10	pract	pract	NOUN
dpc-4237	1	11	concept	concept	NOUN
dpc-4237	1	12	.	.	PUNCT
dpc-4237	2	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	2	2	1	1	NUM
dpc-4237	2	3	evaluation	evaluation	NOUN
dpc-4237	2	4	of	of	ADP
dpc-4237	2	5	serum	serum	NOUN
dpc-4237	2	6	zonulin	zonulin	PROPN
dpc-4237	2	7	level	level	NOUN
dpc-4237	2	8	and	and	CCONJ
dpc-4237	2	9	intestinal	intestinal	ADJ
dpc-4237	2	10	permeability	permeability	NOUN
dpc-4237	2	11	in	in	ADP
dpc-4237	2	12	patients	patient	NOUN
dpc-4237	2	13	with	with	ADP
dpc-4237	2	14	chronic	chronic	ADJ
dpc-4237	2	15	spontaneous	spontaneous	ADJ
dpc-4237	2	16	urticaria	urticaria	NOUN
dpc-4237	2	17	and	and	CCONJ
dpc-4237	2	18	the	the	DET
dpc-4237	2	19	relationship	relationship	NOUN
dpc-4237	2	20	between	between	ADP
dpc-4237	2	21	serum	serum	NOUN
dpc-4237	2	22	zonulin	zonulin	PROPN
dpc-4237	2	23	level	level	NOUN
dpc-4237	2	24	and	and	CCONJ
dpc-4237	2	25	disease	disease	NOUN
dpc-4237	2	26	severity	severity	NOUN
dpc-4237	2	27	simge	simge	NOUN
dpc-4237	2	28	ünal1	ünal1	PROPN
dpc-4237	2	29	,	,	PUNCT
dpc-4237	2	30	selda	selda	PROPN
dpc-4237	2	31	pelin	pelin	PROPN
dpc-4237	2	32	kartal1	kartal1	PROPN
dpc-4237	2	33	,	,	PUNCT
dpc-4237	2	34	ahmet	ahmet	PROPN
dpc-4237	2	35	özsoy2	özsoy2	PROPN
dpc-4237	2	36	,	,	PUNCT
dpc-4237	2	37	fevzi	fevzi	PROPN
dpc-4237	2	38	nuri	nuri	PROPN
dpc-4237	2	39	aydin2	aydin2	PROPN
dpc-4237	2	40	1	1	NUM
dpc-4237	2	41	dışkapı	dışkapı	PROPN
dpc-4237	2	42	yıldırım	yıldırım	PROPN
dpc-4237	2	43	beyazıt	beyazıt	PROPN
dpc-4237	2	44	hospital	hospital	PROPN
dpc-4237	2	45	,	,	PUNCT
dpc-4237	2	46	department	department	NOUN
dpc-4237	2	47	of	of	ADP
dpc-4237	2	48	dermatology	dermatology	NOUN
dpc-4237	2	49	and	and	CCONJ
dpc-4237	2	50	venereology	venereology	NOUN
dpc-4237	2	51	,	,	PUNCT
dpc-4237	2	52	ankara	ankara	PROPN
dpc-4237	2	53	,	,	PUNCT
dpc-4237	2	54	turkey	turkey	NOUN
dpc-4237	2	55	2	2	NUM
dpc-4237	2	56	dışkapı	dışkapı	PROPN
dpc-4237	2	57	yıldırım	yıldırım	PROPN
dpc-4237	2	58	beyazıt	beyazıt	PROPN
dpc-4237	2	59	hospital	hospital	PROPN
dpc-4237	2	60	,	,	PUNCT
dpc-4237	2	61	department	department	NOUN
dpc-4237	2	62	of	of	ADP
dpc-4237	2	63	clinic	clinic	NOUN
dpc-4237	2	64	biochemistry	biochemistry	NOUN
dpc-4237	2	65	,	,	PUNCT
dpc-4237	2	66	ankara	ankara	PROPN
dpc-4237	2	67	,	,	PUNCT
dpc-4237	2	68	turkey	turkey	PROPN
dpc-4237	2	69	key	key	ADJ
dpc-4237	2	70	words	word	NOUN
dpc-4237	2	71	:	:	PUNCT
dpc-4237	2	72	 	 	SPACE
dpc-4237	2	73	chronic	chronic	ADJ
dpc-4237	2	74	spontaneous	spontaneous	ADJ
dpc-4237	2	75	urticaria	urticaria	NOUN
dpc-4237	2	76	,	,	PUNCT
dpc-4237	2	77	autoimmune	autoimmune	ADJ
dpc-4237	2	78	urticaria	urticaria	NOUN
dpc-4237	2	79	,	,	PUNCT
dpc-4237	2	80	anti	anti	ADJ
dpc-4237	2	81	-	-	ADJ
dpc-4237	2	82	ige	ige	ADJ
dpc-4237	2	83	,	,	PUNCT
dpc-4237	2	84	intestinal	intestinal	ADJ
dpc-4237	2	85	permeability	permeability	NOUN
dpc-4237	2	86	,	,	PUNCT
dpc-4237	2	87	zonulin	zonulin	PROPN
dpc-4237	2	88	citation	citation	NOUN
dpc-4237	2	89	:	:	PUNCT
dpc-4237	2	90	ünal	ünal	PROPN
dpc-4237	2	91	s	s	PROPN
dpc-4237	2	92	,	,	PUNCT
dpc-4237	2	93	kartal	kartal	ADJ
dpc-4237	2	94	sp	sp	NOUN
dpc-4237	2	95	,	,	PUNCT
dpc-4237	2	96	özsoy	özsoy	NOUN
dpc-4237	2	97	a	a	PRON
dpc-4237	2	98	,	,	PUNCT
dpc-4237	2	99	aydin	aydin	NOUN
dpc-4237	2	100	fn	fn	NOUN
dpc-4237	2	101	.	.	PUNCT
dpc-4237	3	1	evaluation	evaluation	NOUN
dpc-4237	3	2	of	of	ADP
dpc-4237	3	3	serum	serum	NOUN
dpc-4237	3	4	zonulin	zonulin	PROPN
dpc-4237	3	5	level	level	NOUN
dpc-4237	3	6	and	and	CCONJ
dpc-4237	3	7	intestinal	intestinal	ADJ
dpc-4237	3	8	permeability	permeability	NOUN
dpc-4237	3	9	in	in	ADP
dpc-4237	3	10	patients	patient	NOUN
dpc-4237	3	11	with	with	ADP
dpc-4237	3	12	chronic	chronic	ADJ
dpc-4237	3	13	spontaneous	spontaneous	ADJ
dpc-4237	3	14	urticaria	urticaria	NOUN
dpc-4237	3	15	and	and	CCONJ
dpc-4237	3	16	the	the	DET
dpc-4237	3	17	relationship	relationship	NOUN
dpc-4237	3	18	between	between	ADP
dpc-4237	3	19	serum	serum	NOUN
dpc-4237	3	20	zonulin	zonulin	PROPN
dpc-4237	3	21	level	level	NOUN
dpc-4237	3	22	and	and	CCONJ
dpc-4237	3	23	disease	disease	NOUN
dpc-4237	3	24	severity	severity	NOUN
dpc-4237	3	25	.	.	PUNCT
dpc-4237	4	1	dermatol	dermatol	NOUN
dpc-4237	4	2	pract	pract	PROPN
dpc-4237	4	3	concept	concept	NOUN
dpc-4237	4	4	.	.	PUNCT
dpc-4237	5	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	5	2	.	.	PUNCT
dpc-4237	6	1	doi	doi	PROPN
dpc-4237	6	2	:	:	PUNCT
dpc-4237	6	3	https://doi.org/10.5826/dpc.1501a4237	https://doi.org/10.5826/dpc.1501a4237	PROPN
dpc-4237	6	4	accepted	accept	VERB
dpc-4237	6	5	:	:	PUNCT
dpc-4237	6	6	september	september	PROPN
dpc-4237	6	7	6	6	NUM
dpc-4237	6	8	,	,	PUNCT
dpc-4237	6	9	2024	2024	NUM
dpc-4237	6	10	;	;	PUNCT
dpc-4237	6	11	published	publish	VERB
dpc-4237	6	12	:	:	PUNCT
dpc-4237	7	1	january	january	PROPN
dpc-4237	7	2	2025	2025	NUM
dpc-4237	7	3	copyright	copyright	NOUN
dpc-4237	7	4	:	:	PUNCT
dpc-4237	7	5	©	©	PROPN
dpc-4237	7	6	2024	2024	NUM
dpc-4237	7	7	ünal	ünal	PROPN
dpc-4237	7	8	et	et	PROPN
dpc-4237	7	9	al	al	PROPN
dpc-4237	7	10	.	.	PUNCT
dpc-4237	8	1	this	this	PRON
dpc-4237	8	2	is	be	AUX
dpc-4237	8	3	an	an	DET
dpc-4237	8	4	open	open	ADJ
dpc-4237	8	5	-	-	PUNCT
dpc-4237	8	6	access	access	NOUN
dpc-4237	8	7	article	article	NOUN
dpc-4237	8	8	distributed	distribute	VERB
dpc-4237	8	9	under	under	ADP
dpc-4237	8	10	the	the	DET
dpc-4237	8	11	terms	term	NOUN
dpc-4237	8	12	of	of	ADP
dpc-4237	8	13	the	the	DET
dpc-4237	8	14	creative	creative	ADJ
dpc-4237	8	15	commons	common	NOUN
dpc-4237	8	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-4237	8	17	license	license	NOUN
dpc-4237	8	18	(	(	PUNCT
dpc-4237	8	19	by	by	ADP
dpc-4237	8	20	-	-	PUNCT
dpc-4237	8	21	nc-4.0	nc-4.0	NOUN
dpc-4237	8	22	)	)	PUNCT
dpc-4237	8	23	,	,	PUNCT
dpc-4237	8	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-4237	8	25	,	,	PUNCT
dpc-4237	8	26	which	which	PRON
dpc-4237	8	27	permits	permit	VERB
dpc-4237	8	28	unrestricted	unrestricted	ADJ
dpc-4237	8	29	noncommercial	noncommercial	ADJ
dpc-4237	8	30	use	use	NOUN
dpc-4237	8	31	,	,	PUNCT
dpc-4237	8	32	distribution	distribution	NOUN
dpc-4237	8	33	,	,	PUNCT
dpc-4237	8	34	and	and	CCONJ
dpc-4237	8	35	reproduction	reproduction	NOUN
dpc-4237	8	36	in	in	ADP
dpc-4237	8	37	any	any	DET
dpc-4237	8	38	medium	medium	NOUN
dpc-4237	8	39	,	,	PUNCT
dpc-4237	8	40	provided	provide	VERB
dpc-4237	8	41	the	the	DET
dpc-4237	8	42	original	original	ADJ
dpc-4237	8	43	authors	author	NOUN
dpc-4237	8	44	and	and	CCONJ
dpc-4237	8	45	source	source	NOUN
dpc-4237	8	46	are	be	AUX
dpc-4237	8	47	credited	credit	VERB
dpc-4237	8	48	.	.	PUNCT
dpc-4237	9	1	funding	funding	NOUN
dpc-4237	9	2	:	:	PUNCT
dpc-4237	9	3	none	none	NOUN
dpc-4237	9	4	.	.	PUNCT
dpc-4237	10	1	competing	compete	VERB
dpc-4237	10	2	interests	interest	NOUN
dpc-4237	10	3	:	:	PUNCT
dpc-4237	10	4	none	none	NOUN
dpc-4237	10	5	.	.	PUNCT
dpc-4237	11	1	authorship	authorship	NOUN
dpc-4237	11	2	:	:	PUNCT
dpc-4237	11	3	all	all	DET
dpc-4237	11	4	authors	author	NOUN
dpc-4237	11	5	have	have	AUX
dpc-4237	11	6	contributed	contribute	VERB
dpc-4237	11	7	significantly	significantly	ADV
dpc-4237	11	8	to	to	ADP
dpc-4237	11	9	this	this	DET
dpc-4237	11	10	publication	publication	NOUN
dpc-4237	11	11	.	.	PUNCT
dpc-4237	12	1	corresponding	correspond	VERB
dpc-4237	12	2	author	author	NOUN
dpc-4237	12	3	:	:	PUNCT
dpc-4237	12	4	simge	simge	NOUN
dpc-4237	12	5	ünal	ünal	ADJ
dpc-4237	12	6	,	,	PUNCT
dpc-4237	12	7	uşak	uşak	ADJ
dpc-4237	12	8	training	training	NOUN
dpc-4237	12	9	and	and	CCONJ
dpc-4237	12	10	research	research	NOUN
dpc-4237	12	11	hospital	hospital	NOUN
dpc-4237	12	12	,	,	PUNCT
dpc-4237	12	13	department	department	NOUN
dpc-4237	12	14	of	of	ADP
dpc-4237	12	15	dermatology	dermatology	NOUN
dpc-4237	12	16	and	and	CCONJ
dpc-4237	12	17	venereology	venereology	NOUN
dpc-4237	12	18	,	,	PUNCT
dpc-4237	12	19	uşak	uşak	NOUN
dpc-4237	12	20	,	,	PUNCT
dpc-4237	12	21	turkey	turkey	PROPN
dpc-4237	12	22	.	.	PUNCT
dpc-4237	13	1	phone	phone	NOUN
dpc-4237	13	2	:	:	PUNCT
dpc-4237	14	1	+90	+90	NOUN
dpc-4237	14	2	507	507	NUM
dpc-4237	14	3	072	072	NUM
dpc-4237	14	4	85	85	NUM
dpc-4237	14	5	15	15	NUM
dpc-4237	14	6	;	;	PUNCT
dpc-4237	14	7	e	e	X
dpc-4237	14	8	-	-	NOUN
dpc-4237	14	9	mail	mail	NOUN
dpc-4237	14	10	:	:	PUNCT
dpc-4237	14	11	unalsimgee45@gmail.com	unalsimgee45@gmail.com	X
dpc-4237	14	12	introduction	introduction	NOUN
dpc-4237	14	13	:	:	PUNCT
dpc-4237	14	14	an	an	DET
dpc-4237	14	15	emerging	emerge	VERB
dpc-4237	14	16	hypothesis	hypothesis	NOUN
dpc-4237	14	17	suggests	suggest	VERB
dpc-4237	14	18	a	a	DET
dpc-4237	14	19	potential	potential	ADJ
dpc-4237	14	20	link	link	NOUN
dpc-4237	14	21	between	between	ADP
dpc-4237	14	22	enhanced	enhanced	ADJ
dpc-4237	14	23	intestinal	intestinal	ADJ
dpc-4237	14	24	permeability	permeability	NOUN
dpc-4237	14	25	and	and	CCONJ
dpc-4237	14	26	the	the	DET
dpc-4237	14	27	advancement	advancement	NOUN
dpc-4237	14	28	of	of	ADP
dpc-4237	14	29	chronic	chronic	ADJ
dpc-4237	14	30	spontaneous	spontaneous	ADJ
dpc-4237	14	31	urticaria	urticaria	NOUN
dpc-4237	14	32	(	(	PUNCT
dpc-4237	14	33	csu	csu	PROPN
dpc-4237	14	34	)	)	PUNCT
dpc-4237	14	35	.	.	PUNCT
dpc-4237	15	1	objective	objective	NOUN
dpc-4237	15	2	:	:	PUNCT
dpc-4237	15	3	this	this	DET
dpc-4237	15	4	study	study	NOUN
dpc-4237	15	5	aimed	aim	VERB
dpc-4237	15	6	to	to	PART
dpc-4237	15	7	investigate	investigate	VERB
dpc-4237	15	8	the	the	DET
dpc-4237	15	9	role	role	NOUN
dpc-4237	15	10	of	of	ADP
dpc-4237	15	11	intestinal	intestinal	ADJ
dpc-4237	15	12	permeability	permeability	NOUN
dpc-4237	15	13	in	in	ADP
dpc-4237	15	14	the	the	DET
dpc-4237	15	15	etiopathogenesis	etiopathogenesis	NOUN
dpc-4237	15	16	of	of	ADP
dpc-4237	15	17	csu	csu	VERB
dpc-4237	15	18	by	by	ADP
dpc-4237	15	19	measuring	measure	VERB
dpc-4237	15	20	serum	serum	NOUN
dpc-4237	15	21	zonulin	zonulin	PROPN
dpc-4237	15	22	levels	level	NOUN
dpc-4237	15	23	,	,	PUNCT
dpc-4237	15	24	a	a	DET
dpc-4237	15	25	marker	marker	NOUN
dpc-4237	15	26	of	of	ADP
dpc-4237	15	27	intestinal	intestinal	ADJ
dpc-4237	15	28	permeability	permeability	NOUN
dpc-4237	15	29	,	,	PUNCT
dpc-4237	15	30	in	in	ADP
dpc-4237	15	31	both	both	DET
dpc-4237	15	32	csu	csu	NOUN
dpc-4237	15	33	patients	patient	NOUN
dpc-4237	15	34	and	and	CCONJ
dpc-4237	15	35	control	control	NOUN
dpc-4237	15	36	subjects	subject	NOUN
dpc-4237	15	37	.	.	PUNCT
dpc-4237	16	1	additionally	additionally	ADV
dpc-4237	16	2	,	,	PUNCT
dpc-4237	16	3	the	the	DET
dpc-4237	16	4	study	study	NOUN
dpc-4237	16	5	sought	seek	VERB
dpc-4237	16	6	to	to	PART
dpc-4237	16	7	explore	explore	VERB
dpc-4237	16	8	the	the	DET
dpc-4237	16	9	correlation	correlation	NOUN
dpc-4237	16	10	between	between	ADP
dpc-4237	16	11	the	the	DET
dpc-4237	16	12	severity	severity	NOUN
dpc-4237	16	13	of	of	ADP
dpc-4237	16	14	the	the	DET
dpc-4237	16	15	illness	illness	NOUN
dpc-4237	16	16	and	and	CCONJ
dpc-4237	16	17	zonulin	zonulin	PROPN
dpc-4237	16	18	levels	level	NOUN
dpc-4237	16	19	.	.	PUNCT
dpc-4237	17	1	methods	method	NOUN
dpc-4237	17	2	:	:	PUNCT
dpc-4237	17	3	the	the	DET
dpc-4237	17	4	study	study	NOUN
dpc-4237	17	5	involved	involve	VERB
dpc-4237	17	6	61	61	NUM
dpc-4237	17	7	patients	patient	NOUN
dpc-4237	17	8	with	with	ADP
dpc-4237	17	9	csu	csu	PROPN
dpc-4237	17	10	and	and	CCONJ
dpc-4237	17	11	59	59	NUM
dpc-4237	17	12	healthy	healthy	ADJ
dpc-4237	17	13	control	control	NOUN
dpc-4237	17	14	individuals	individual	NOUN
dpc-4237	17	15	.	.	PUNCT
dpc-4237	18	1	for	for	ADP
dpc-4237	18	2	the	the	DET
dpc-4237	18	3	csu	csu	PROPN
dpc-4237	18	4	patients	patient	NOUN
dpc-4237	18	5	,	,	PUNCT
dpc-4237	18	6	comprehensive	comprehensive	ADJ
dpc-4237	18	7	data	datum	NOUN
dpc-4237	18	8	were	be	AUX
dpc-4237	18	9	collected	collect	VERB
dpc-4237	18	10	encompassing	encompass	VERB
dpc-4237	18	11	various	various	ADJ
dpc-4237	18	12	aspects	aspect	NOUN
dpc-4237	18	13	:	:	PUNCT
dpc-4237	18	14	age	age	NOUN
dpc-4237	18	15	at	at	ADP
dpc-4237	18	16	onset	onset	NOUN
dpc-4237	18	17	of	of	ADP
dpc-4237	18	18	the	the	DET
dpc-4237	18	19	condition	condition	NOUN
dpc-4237	18	20	,	,	PUNCT
dpc-4237	18	21	duration	duration	NOUN
dpc-4237	18	22	of	of	ADP
dpc-4237	18	23	the	the	DET
dpc-4237	18	24	most	most	ADV
dpc-4237	18	25	recent	recent	ADJ
dpc-4237	18	26	attack	attack	NOUN
dpc-4237	18	27	,	,	PUNCT
dpc-4237	18	28	presence	presence	NOUN
dpc-4237	18	29	of	of	ADP
dpc-4237	18	30	any	any	DET
dpc-4237	18	31	comorbid	comorbid	NOUN
dpc-4237	18	32	conditions	condition	NOUN
dpc-4237	18	33	,	,	PUNCT
dpc-4237	18	34	dosage	dosage	NOUN
dpc-4237	18	35	of	of	ADP
dpc-4237	18	36	antihistamines	antihistamine	NOUN
dpc-4237	18	37	being	be	AUX
dpc-4237	18	38	used	use	VERB
dpc-4237	18	39	,	,	PUNCT
dpc-4237	18	40	and	and	CCONJ
dpc-4237	18	41	urticaria	urticaria	NOUN
dpc-4237	18	42	activity	activity	NOUN
dpc-4237	18	43	score	score	NOUN
dpc-4237	18	44	as	as	ADV
dpc-4237	18	45	well	well	ADV
dpc-4237	18	46	as	as	ADP
dpc-4237	18	47	detailed	detailed	ADJ
dpc-4237	18	48	personal	personal	ADJ
dpc-4237	18	49	and	and	CCONJ
dpc-4237	18	50	family	family	NOUN
dpc-4237	18	51	medical	medical	ADJ
dpc-4237	18	52	histories	history	NOUN
dpc-4237	18	53	.	.	PUNCT
dpc-4237	19	1	additionally	additionally	ADV
dpc-4237	19	2	,	,	PUNCT
dpc-4237	19	3	demographic	demographic	ADJ
dpc-4237	19	4	information	information	NOUN
dpc-4237	19	5	for	for	ADP
dpc-4237	19	6	these	these	DET
dpc-4237	19	7	patients	patient	NOUN
dpc-4237	19	8	was	be	AUX
dpc-4237	19	9	also	also	ADV
dpc-4237	19	10	meticulously	meticulously	ADV
dpc-4237	19	11	documented	document	VERB
dpc-4237	19	12	.	.	PUNCT
dpc-4237	20	1	result	result	VERB
dpc-4237	20	2	:	:	PUNCT
dpc-4237	20	3	the	the	DET
dpc-4237	20	4	study	study	NOUN
dpc-4237	20	5	revealed	reveal	VERB
dpc-4237	20	6	a	a	DET
dpc-4237	20	7	statistically	statistically	ADV
dpc-4237	20	8	significant	significant	ADJ
dpc-4237	20	9	difference	difference	NOUN
dpc-4237	20	10	in	in	ADP
dpc-4237	20	11	zonulin	zonulin	PROPN
dpc-4237	20	12	levels	level	NOUN
dpc-4237	20	13	between	between	ADP
dpc-4237	20	14	the	the	DET
dpc-4237	20	15	csu	csu	PROPN
dpc-4237	20	16	patient	patient	PROPN
dpc-4237	20	17	group	group	NOUN
dpc-4237	20	18	and	and	CCONJ
dpc-4237	20	19	the	the	DET
dpc-4237	20	20	control	control	NOUN
dpc-4237	20	21	group	group	NOUN
dpc-4237	20	22	,	,	PUNCT
dpc-4237	20	23	with	with	ADP
dpc-4237	20	24	a	a	DET
dpc-4237	20	25	p	p	NOUN
dpc-4237	20	26	-	-	PUNCT
dpc-4237	20	27	value	value	NOUN
dpc-4237	20	28	of	of	ADP
dpc-4237	20	29	0.000	0.000	NUM
dpc-4237	20	30	,	,	PUNCT
dpc-4237	20	31	indicating	indicate	VERB
dpc-4237	20	32	a	a	DET
dpc-4237	20	33	highly	highly	ADV
dpc-4237	20	34	significant	significant	ADJ
dpc-4237	20	35	disparity	disparity	NOUN
dpc-4237	20	36	.	.	PUNCT
dpc-4237	21	1	furthermore	furthermore	ADV
dpc-4237	21	2	,	,	PUNCT
dpc-4237	21	3	among	among	ADP
dpc-4237	21	4	the	the	DET
dpc-4237	21	5	csu	csu	PROPN
dpc-4237	21	6	patients	patient	NOUN
dpc-4237	21	7	,	,	PUNCT
dpc-4237	21	8	those	those	PRON
dpc-4237	21	9	who	who	PRON
dpc-4237	21	10	presented	present	VERB
dpc-4237	21	11	with	with	ADP
dpc-4237	21	12	angioedema	angioedema	NOUN
dpc-4237	21	13	exhibited	exhibit	VERB
dpc-4237	21	14	considerably	considerably	ADV
dpc-4237	21	15	higher	high	ADJ
dpc-4237	21	16	zonulin	zonulin	PROPN
dpc-4237	21	17	levels	level	NOUN
dpc-4237	21	18	compared	compare	VERB
dpc-4237	21	19	to	to	ADP
dpc-4237	21	20	those	those	PRON
dpc-4237	21	21	without	without	ADP
dpc-4237	21	22	angioedema	angioedema	NOUN
dpc-4237	21	23	.	.	PUNCT
dpc-4237	22	1	this	this	DET
dpc-4237	22	2	variation	variation	NOUN
dpc-4237	22	3	in	in	ADP
dpc-4237	22	4	zonulin	zonulin	PROPN
dpc-4237	22	5	levels	level	NOUN
dpc-4237	22	6	based	base	VERB
dpc-4237	22	7	on	on	ADP
dpc-4237	22	8	the	the	DET
dpc-4237	22	9	presence	presence	NOUN
dpc-4237	22	10	of	of	ADP
dpc-4237	22	11	angioedema	angioedema	NOUN
dpc-4237	22	12	was	be	AUX
dpc-4237	22	13	also	also	ADV
dpc-4237	22	14	statistically	statistically	ADV
dpc-4237	22	15	significant	significant	ADJ
dpc-4237	22	16	,	,	PUNCT
dpc-4237	22	17	with	with	ADP
dpc-4237	22	18	a	a	DET
dpc-4237	22	19	p	p	NOUN
dpc-4237	22	20	-	-	PUNCT
dpc-4237	22	21	value	value	NOUN
dpc-4237	22	22	of	of	ADP
dpc-4237	22	23	0.023	0.023	NUM
dpc-4237	22	24	.	.	PUNCT
dpc-4237	23	1	abstract	abstract	ADJ
dpc-4237	23	2	2	2	NUM
dpc-4237	23	3	original	original	ADJ
dpc-4237	23	4	article	article	NOUN
dpc-4237	23	5	|	|	ADV
dpc-4237	23	6	dermatol	dermatol	ADJ
dpc-4237	23	7	pract	pract	NOUN
dpc-4237	23	8	concept	concept	NOUN
dpc-4237	23	9	.	.	PUNCT
dpc-4237	24	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	24	2	introduction	introduction	NOUN
dpc-4237	24	3	urticaria	urticaria	NOUN
dpc-4237	24	4	is	be	AUX
dpc-4237	24	5	an	an	DET
dpc-4237	24	6	inflammatory	inflammatory	ADJ
dpc-4237	24	7	disease	disease	NOUN
dpc-4237	24	8	affecting	affect	VERB
dpc-4237	24	9	the	the	DET
dpc-4237	24	10	superficial	superficial	ADJ
dpc-4237	24	11	dermis	dermis	NOUN
dpc-4237	24	12	,	,	PUNCT
dpc-4237	24	13	marked	mark	VERB
dpc-4237	24	14	by	by	ADP
dpc-4237	24	15	itchy	itchy	ADJ
dpc-4237	24	16	red	red	ADJ
dpc-4237	24	17	papules	papule	NOUN
dpc-4237	24	18	and	and	CCONJ
dpc-4237	24	19	plaques	plaque	NOUN
dpc-4237	24	20	that	that	PRON
dpc-4237	24	21	last	last	VERB
dpc-4237	24	22	less	less	ADJ
dpc-4237	24	23	than	than	ADP
dpc-4237	24	24	24	24	NUM
dpc-4237	24	25	hours	hour	NOUN
dpc-4237	24	26	.	.	PUNCT
dpc-4237	25	1	it	it	PRON
dpc-4237	25	2	can	can	AUX
dpc-4237	25	3	also	also	ADV
dpc-4237	25	4	be	be	AUX
dpc-4237	25	5	accompanied	accompany	VERB
dpc-4237	25	6	by	by	ADP
dpc-4237	25	7	angioedema	angioedema	NOUN
dpc-4237	25	8	.	.	PUNCT
dpc-4237	26	1	if	if	SCONJ
dpc-4237	26	2	the	the	DET
dpc-4237	26	3	condition	condition	NOUN
dpc-4237	26	4	persists	persist	VERB
dpc-4237	26	5	for	for	ADP
dpc-4237	26	6	less	less	ADJ
dpc-4237	26	7	than	than	ADP
dpc-4237	26	8	six	six	NUM
dpc-4237	26	9	weeks	week	NOUN
dpc-4237	26	10	,	,	PUNCT
dpc-4237	26	11	it	it	PRON
dpc-4237	26	12	is	be	AUX
dpc-4237	26	13	classified	classify	VERB
dpc-4237	26	14	as	as	ADP
dpc-4237	26	15	acute	acute	ADJ
dpc-4237	26	16	urticaria	urticaria	NOUN
dpc-4237	26	17	;	;	PUNCT
dpc-4237	26	18	if	if	SCONJ
dpc-4237	26	19	it	it	PRON
dpc-4237	26	20	lasts	last	VERB
dpc-4237	26	21	six	six	NUM
dpc-4237	26	22	weeks	week	NOUN
dpc-4237	26	23	or	or	CCONJ
dpc-4237	26	24	longer	long	ADV
dpc-4237	26	25	,	,	PUNCT
dpc-4237	26	26	it	it	PRON
dpc-4237	26	27	is	be	AUX
dpc-4237	26	28	considered	consider	VERB
dpc-4237	26	29	chronic	chronic	ADJ
dpc-4237	26	30	urticaria	urticaria	NOUN
dpc-4237	26	31	.	.	PUNCT
dpc-4237	27	1	chronic	chronic	ADJ
dpc-4237	27	2	urticaria	urticaria	NOUN
dpc-4237	27	3	is	be	AUX
dpc-4237	27	4	further	far	ADV
dpc-4237	27	5	divided	divide	VERB
dpc-4237	27	6	into	into	ADP
dpc-4237	27	7	two	two	NUM
dpc-4237	27	8	main	main	ADJ
dpc-4237	27	9	categories	category	NOUN
dpc-4237	27	10	:	:	PUNCT
dpc-4237	27	11	chronic	chronic	ADJ
dpc-4237	27	12	spontaneous	spontaneous	ADJ
dpc-4237	27	13	urticaria	urticaria	NOUN
dpc-4237	27	14	and	and	CCONJ
dpc-4237	27	15	chronic	chronic	ADJ
dpc-4237	27	16	inducible	inducible	ADJ
dpc-4237	27	17	urticaria	urticaria	NOUN
dpc-4237	27	18	[	[	X
dpc-4237	27	19	1	1	NUM
dpc-4237	27	20	]	]	PUNCT
dpc-4237	27	21	.	.	PUNCT
dpc-4237	28	1	although	although	SCONJ
dpc-4237	28	2	80	80	NUM
dpc-4237	28	3	%	%	NOUN
dpc-4237	28	4	of	of	ADP
dpc-4237	28	5	individuals	individual	NOUN
dpc-4237	28	6	with	with	ADP
dpc-4237	28	7	chronic	chronic	ADJ
dpc-4237	28	8	urticaria	urticaria	NOUN
dpc-4237	28	9	experience	experience	NOUN
dpc-4237	28	10	remission	remission	NOUN
dpc-4237	28	11	within	within	ADP
dpc-4237	28	12	a	a	DET
dpc-4237	28	13	year	year	NOUN
dpc-4237	28	14	,	,	PUNCT
dpc-4237	28	15	studies	study	NOUN
dpc-4237	28	16	show	show	VERB
dpc-4237	28	17	that	that	SCONJ
dpc-4237	28	18	11	11	NUM
dpc-4237	28	19	%	%	NOUN
dpc-4237	28	20	still	still	ADV
dpc-4237	28	21	have	have	VERB
dpc-4237	28	22	the	the	DET
dpc-4237	28	23	condition	condition	NOUN
dpc-4237	28	24	after	after	ADP
dpc-4237	28	25	five	five	NUM
dpc-4237	28	26	years	year	NOUN
dpc-4237	29	1	[	[	X
dpc-4237	29	2	2	2	NUM
dpc-4237	29	3	]	]	PUNCT
dpc-4237	29	4	.	.	PUNCT
dpc-4237	30	1	the	the	DET
dpc-4237	30	2	exact	exact	ADJ
dpc-4237	30	3	cause	cause	NOUN
dpc-4237	30	4	of	of	ADP
dpc-4237	30	5	chronic	chronic	ADJ
dpc-4237	30	6	urticaria	urticaria	NOUN
dpc-4237	30	7	is	be	AUX
dpc-4237	30	8	unknown	unknown	ADJ
dpc-4237	30	9	,	,	PUNCT
dpc-4237	30	10	but	but	CCONJ
dpc-4237	30	11	autoimmunity	autoimmunity	NOUN
dpc-4237	30	12	is	be	AUX
dpc-4237	30	13	believed	believe	VERB
dpc-4237	30	14	to	to	PART
dpc-4237	30	15	play	play	VERB
dpc-4237	30	16	a	a	DET
dpc-4237	30	17	role	role	NOUN
dpc-4237	30	18	in	in	ADP
dpc-4237	30	19	about	about	ADV
dpc-4237	30	20	45	45	NUM
dpc-4237	30	21	%	%	NOUN
dpc-4237	30	22	of	of	ADP
dpc-4237	30	23	cases	case	NOUN
dpc-4237	30	24	[	[	X
dpc-4237	30	25	3	3	NUM
dpc-4237	30	26	]	]	PUNCT
dpc-4237	30	27	.	.	PUNCT
dpc-4237	31	1	there	there	PRON
dpc-4237	31	2	are	be	VERB
dpc-4237	31	3	two	two	NUM
dpc-4237	31	4	primary	primary	ADJ
dpc-4237	31	5	theories	theory	NOUN
dpc-4237	31	6	regarding	regard	VERB
dpc-4237	31	7	the	the	DET
dpc-4237	31	8	pathogenesis	pathogenesis	NOUN
dpc-4237	31	9	of	of	ADP
dpc-4237	31	10	chronic	chronic	ADJ
dpc-4237	31	11	urticaria	urticaria	NOUN
dpc-4237	31	12	.	.	PUNCT
dpc-4237	32	1	the	the	DET
dpc-4237	32	2	first	first	ADJ
dpc-4237	32	3	theory	theory	NOUN
dpc-4237	32	4	suggests	suggest	VERB
dpc-4237	32	5	that	that	SCONJ
dpc-4237	32	6	mast	mast	NOUN
dpc-4237	32	7	cells	cell	NOUN
dpc-4237	32	8	and	and	CCONJ
dpc-4237	32	9	basophils	basophil	NOUN
dpc-4237	32	10	have	have	VERB
dpc-4237	32	11	functional	functional	ADJ
dpc-4237	32	12	or	or	CCONJ
dpc-4237	32	13	trafficking	traffic	VERB
dpc-4237	32	14	defects	defect	NOUN
dpc-4237	32	15	due	due	ADJ
dpc-4237	32	16	to	to	ADP
dpc-4237	32	17	dysregulated	dysregulated	ADJ
dpc-4237	32	18	intracellular	intracellular	ADJ
dpc-4237	32	19	signaling	signal	VERB
dpc-4237	32	20	pathways	pathway	NOUN
dpc-4237	32	21	.	.	PUNCT
dpc-4237	33	1	the	the	DET
dpc-4237	33	2	second	second	ADJ
dpc-4237	33	3	theory	theory	NOUN
dpc-4237	33	4	posits	posit	VERB
dpc-4237	33	5	the	the	DET
dpc-4237	33	6	development	development	NOUN
dpc-4237	33	7	of	of	ADP
dpc-4237	33	8	autoantibodies	autoantibody	NOUN
dpc-4237	33	9	against	against	ADP
dpc-4237	33	10	fcεriα	fcεriα	NOUN
dpc-4237	33	11	or	or	CCONJ
dpc-4237	33	12	ige	ige	PROPN
dpc-4237	33	13	in	in	ADP
dpc-4237	33	14	these	these	DET
dpc-4237	33	15	cells	cell	NOUN
dpc-4237	33	16	[	[	X
dpc-4237	33	17	4	4	NUM
dpc-4237	33	18	]	]	PUNCT
dpc-4237	33	19	.	.	PUNCT
dpc-4237	34	1	for	for	ADP
dpc-4237	34	2	individuals	individual	NOUN
dpc-4237	34	3	with	with	ADP
dpc-4237	34	4	a	a	DET
dpc-4237	34	5	genetic	genetic	ADJ
dpc-4237	34	6	predisposition	predisposition	NOUN
dpc-4237	34	7	,	,	PUNCT
dpc-4237	34	8	recent	recent	ADJ
dpc-4237	34	9	research	research	NOUN
dpc-4237	34	10	indicates	indicate	VERB
dpc-4237	34	11	that	that	SCONJ
dpc-4237	34	12	compromised	compromise	VERB
dpc-4237	34	13	gut	gut	NOUN
dpc-4237	34	14	barrier	barrier	NOUN
dpc-4237	34	15	function	function	NOUN
dpc-4237	34	16	may	may	AUX
dpc-4237	34	17	cause	cause	VERB
dpc-4237	34	18	and	and	CCONJ
dpc-4237	34	19	worsen	worsen	VERB
dpc-4237	34	20	autoimmune	autoimmune	ADJ
dpc-4237	34	21	disorders	disorder	NOUN
dpc-4237	34	22	[	[	X
dpc-4237	34	23	5	5	NUM
dpc-4237	34	24	]	]	PUNCT
dpc-4237	34	25	.	.	PUNCT
dpc-4237	35	1	the	the	DET
dpc-4237	35	2	intestinal	intestinal	ADJ
dpc-4237	35	3	barrier	barrier	NOUN
dpc-4237	35	4	’s	’s	PART
dpc-4237	35	5	function	function	NOUN
dpc-4237	35	6	is	be	AUX
dpc-4237	35	7	regulated	regulate	VERB
dpc-4237	35	8	by	by	ADP
dpc-4237	35	9	immunological	immunological	ADJ
dpc-4237	35	10	,	,	PUNCT
dpc-4237	35	11	biochemical	biochemical	ADJ
dpc-4237	35	12	,	,	PUNCT
dpc-4237	35	13	and	and	CCONJ
dpc-4237	35	14	physical	physical	ADJ
dpc-4237	35	15	factors	factor	NOUN
dpc-4237	35	16	.	.	PUNCT
dpc-4237	36	1	this	this	DET
dpc-4237	36	2	barrier	barrier	NOUN
dpc-4237	36	3	’s	’s	PART
dpc-4237	36	4	physical	physical	ADJ
dpc-4237	36	5	structure	structure	NOUN
dpc-4237	36	6	includes	include	VERB
dpc-4237	36	7	enterocytes	enterocyte	NOUN
dpc-4237	36	8	,	,	PUNCT
dpc-4237	36	9	tight	tight	ADJ
dpc-4237	36	10	junctions	junction	NOUN
dpc-4237	36	11	(	(	PUNCT
dpc-4237	36	12	tj	tj	NOUN
dpc-4237	36	13	)	)	PUNCT
dpc-4237	36	14	,	,	PUNCT
dpc-4237	36	15	adherent	adherent	ADJ
dpc-4237	36	16	junctions	junction	NOUN
dpc-4237	36	17	,	,	PUNCT
dpc-4237	36	18	desmosomes	desmosome	NOUN
dpc-4237	36	19	,	,	PUNCT
dpc-4237	36	20	mucus	mucus	NOUN
dpc-4237	36	21	,	,	PUNCT
dpc-4237	36	22	and	and	CCONJ
dpc-4237	36	23	commensal	commensal	ADJ
dpc-4237	36	24	bacteria	bacteria	NOUN
dpc-4237	37	1	[	[	X
dpc-4237	37	2	6,7	6,7	NUM
dpc-4237	37	3	]	]	PUNCT
dpc-4237	37	4	.	.	PUNCT
dpc-4237	38	1	when	when	SCONJ
dpc-4237	38	2	the	the	DET
dpc-4237	38	3	intestinal	intestinal	ADJ
dpc-4237	38	4	barrier	barrier	NOUN
dpc-4237	38	5	is	be	AUX
dpc-4237	38	6	disturbed	disturb	VERB
dpc-4237	38	7	,	,	PUNCT
dpc-4237	38	8	a	a	DET
dpc-4237	38	9	condition	condition	NOUN
dpc-4237	38	10	often	often	ADV
dpc-4237	38	11	referred	refer	VERB
dpc-4237	38	12	to	to	ADP
dpc-4237	38	13	as	as	ADP
dpc-4237	38	14	a	a	DET
dpc-4237	38	15	leaky	leaky	ADJ
dpc-4237	38	16	gut	gut	NOUN
dpc-4237	38	17	occurs	occur	NOUN
dpc-4237	38	18	.	.	PUNCT
dpc-4237	39	1	increased	increase	VERB
dpc-4237	39	2	intestinal	intestinal	ADJ
dpc-4237	39	3	permeability	permeability	NOUN
dpc-4237	39	4	allows	allow	VERB
dpc-4237	39	5	commensal	commensal	NOUN
dpc-4237	39	6	microorganisms	microorganism	NOUN
dpc-4237	39	7	,	,	PUNCT
dpc-4237	39	8	bacterial	bacterial	ADJ
dpc-4237	39	9	compounds	compound	NOUN
dpc-4237	39	10	,	,	PUNCT
dpc-4237	39	11	and	and	CCONJ
dpc-4237	39	12	foreign	foreign	ADJ
dpc-4237	39	13	antigens	antigen	NOUN
dpc-4237	39	14	to	to	PART
dpc-4237	39	15	enter	enter	VERB
dpc-4237	39	16	the	the	DET
dpc-4237	39	17	body	body	NOUN
dpc-4237	39	18	uncontrollably	uncontrollably	ADV
dpc-4237	39	19	.	.	PUNCT
dpc-4237	40	1	the	the	DET
dpc-4237	40	2	submucosal	submucosal	NOUN
dpc-4237	40	3	innate	innate	ADJ
dpc-4237	40	4	immune	immune	ADJ
dpc-4237	40	5	system	system	NOUN
dpc-4237	40	6	is	be	AUX
dpc-4237	40	7	activated	activate	VERB
dpc-4237	40	8	in	in	ADP
dpc-4237	40	9	this	this	DET
dpc-4237	40	10	scenario	scenario	NOUN
dpc-4237	40	11	,	,	PUNCT
dpc-4237	40	12	and	and	CCONJ
dpc-4237	40	13	antigen	antigen	ADJ
dpc-4237	40	14	traffic	traffic	NOUN
dpc-4237	40	15	can	can	AUX
dpc-4237	40	16	not	not	PART
dpc-4237	40	17	be	be	AUX
dpc-4237	40	18	regulated	regulate	VERB
dpc-4237	40	19	.	.	PUNCT
dpc-4237	41	1	if	if	SCONJ
dpc-4237	41	2	this	this	DET
dpc-4237	41	3	cycle	cycle	NOUN
dpc-4237	41	4	continues	continue	VERB
dpc-4237	41	5	,	,	PUNCT
dpc-4237	41	6	the	the	DET
dpc-4237	41	7	acquired	acquire	VERB
dpc-4237	41	8	immune	immune	ADJ
dpc-4237	41	9	system	system	NOUN
dpc-4237	41	10	is	be	AUX
dpc-4237	41	11	also	also	ADV
dpc-4237	41	12	activated	activate	VERB
dpc-4237	41	13	,	,	PUNCT
dpc-4237	41	14	leading	lead	VERB
dpc-4237	41	15	to	to	ADP
dpc-4237	41	16	the	the	DET
dpc-4237	41	17	release	release	NOUN
dpc-4237	41	18	of	of	ADP
dpc-4237	41	19	cytokines	cytokine	NOUN
dpc-4237	41	20	such	such	ADJ
dpc-4237	41	21	as	as	ADP
dpc-4237	41	22	ifn	ifn	NOUN
dpc-4237	41	23	-	-	PUNCT
dpc-4237	41	24	γ	γ	X
dpc-4237	41	25	and	and	CCONJ
dpc-4237	41	26	tnf	tnf	PROPN
dpc-4237	41	27	-	-	PUNCT
dpc-4237	41	28	α	α	PROPN
dpc-4237	41	29	and	and	CCONJ
dpc-4237	41	30	further	further	ADJ
dpc-4237	41	31	antigen	antigen	ADJ
dpc-4237	41	32	passage	passage	NOUN
dpc-4237	41	33	.	.	PUNCT
dpc-4237	42	1	this	this	DET
dpc-4237	42	2	results	result	VERB
dpc-4237	42	3	in	in	ADP
dpc-4237	42	4	a	a	DET
dpc-4237	42	5	vicious	vicious	ADJ
dpc-4237	42	6	cycle	cycle	NOUN
dpc-4237	42	7	of	of	ADP
dpc-4237	42	8	uncontrolled	uncontrolled	ADJ
dpc-4237	42	9	antigen	antigen	ADJ
dpc-4237	42	10	traffic	traffic	NOUN
dpc-4237	42	11	[	[	X
dpc-4237	42	12	5	5	NUM
dpc-4237	42	13	]	]	PUNCT
dpc-4237	42	14	.	.	PUNCT
dpc-4237	43	1	in	in	ADP
dpc-4237	43	2	our	our	PRON
dpc-4237	43	3	study	study	NOUN
dpc-4237	43	4	,	,	PUNCT
dpc-4237	43	5	we	we	PRON
dpc-4237	43	6	measured	measure	VERB
dpc-4237	43	7	zonulin	zonulin	PROPN
dpc-4237	43	8	levels	level	NOUN
dpc-4237	43	9	in	in	ADP
dpc-4237	43	10	serum	serum	NOUN
dpc-4237	43	11	to	to	PART
dpc-4237	43	12	evaluate	evaluate	VERB
dpc-4237	43	13	intestinal	intestinal	ADJ
dpc-4237	43	14	permeability	permeability	NOUN
dpc-4237	43	15	.	.	PUNCT
dpc-4237	44	1	tight	tight	ADJ
dpc-4237	44	2	junctions	junction	NOUN
dpc-4237	44	3	between	between	ADP
dpc-4237	44	4	enterocytes	enterocyte	NOUN
dpc-4237	44	5	provide	provide	VERB
dpc-4237	44	6	intestinal	intestinal	ADJ
dpc-4237	44	7	barrier	barrier	NOUN
dpc-4237	44	8	control	control	NOUN
dpc-4237	44	9	,	,	PUNCT
dpc-4237	44	10	and	and	CCONJ
dpc-4237	44	11	zonulin	zonulin	NOUN
dpc-4237	44	12	is	be	AUX
dpc-4237	44	13	a	a	DET
dpc-4237	44	14	protein	protein	NOUN
dpc-4237	44	15	that	that	PRON
dpc-4237	44	16	regulates	regulate	VERB
dpc-4237	44	17	antigen	antigen	ADJ
dpc-4237	44	18	traffic	traffic	NOUN
dpc-4237	44	19	by	by	ADP
dpc-4237	44	20	controlling	control	VERB
dpc-4237	44	21	these	these	DET
dpc-4237	44	22	tj	tj	NOUN
dpc-4237	45	1	[	[	X
dpc-4237	45	2	8	8	NUM
dpc-4237	45	3	]	]	PUNCT
dpc-4237	45	4	.	.	PUNCT
dpc-4237	46	1	zonula	zonula	PROPN
dpc-4237	46	2	occludens	occluden	NOUN
dpc-4237	46	3	toxin	toxin	PROPN
dpc-4237	46	4	(	(	PUNCT
dpc-4237	46	5	zot	zot	PROPN
dpc-4237	46	6	)	)	PUNCT
dpc-4237	46	7	was	be	AUX
dpc-4237	46	8	discovered	discover	VERB
dpc-4237	46	9	during	during	ADP
dpc-4237	46	10	vaccine	vaccine	NOUN
dpc-4237	46	11	development	development	NOUN
dpc-4237	46	12	studies	study	NOUN
dpc-4237	46	13	against	against	ADP
dpc-4237	46	14	vibrio	vibrio	ADJ
dpc-4237	46	15	cholerae	cholerae	PROPN
dpc-4237	46	16	bacteria	bacteria	NOUN
dpc-4237	46	17	[	[	X
dpc-4237	46	18	8	8	NUM
dpc-4237	46	19	]	]	PUNCT
dpc-4237	46	20	.	.	PUNCT
dpc-4237	47	1	this	this	DET
dpc-4237	47	2	discovery	discovery	NOUN
dpc-4237	47	3	illuminated	illuminate	VERB
dpc-4237	47	4	the	the	DET
dpc-4237	47	5	mechanisms	mechanism	NOUN
dpc-4237	47	6	involved	involve	VERB
dpc-4237	47	7	in	in	ADP
dpc-4237	47	8	regulating	regulate	VERB
dpc-4237	47	9	paracellular	paracellular	ADJ
dpc-4237	47	10	transit	transit	NOUN
dpc-4237	47	11	in	in	ADP
dpc-4237	47	12	the	the	DET
dpc-4237	47	13	gut	gut	NOUN
dpc-4237	47	14	.	.	PUNCT
dpc-4237	48	1	zot	zot	PROPN
dpc-4237	48	2	is	be	AUX
dpc-4237	48	3	an	an	DET
dpc-4237	48	4	endogenous	endogenous	ADJ
dpc-4237	48	5	enterotoxin	enterotoxin	NOUN
dpc-4237	48	6	that	that	PRON
dpc-4237	48	7	rapidly	rapidly	ADV
dpc-4237	48	8	and	and	CCONJ
dpc-4237	48	9	reversibly	reversibly	ADV
dpc-4237	48	10	regulates	regulate	VERB
dpc-4237	48	11	tj	tj	NOUN
dpc-4237	48	12	.	.	PUNCT
dpc-4237	49	1	it	it	PRON
dpc-4237	49	2	was	be	AUX
dpc-4237	49	3	believed	believe	VERB
dpc-4237	49	4	to	to	PART
dpc-4237	49	5	mimic	mimic	VERB
dpc-4237	49	6	a	a	DET
dpc-4237	49	7	protein	protein	NOUN
dpc-4237	49	8	that	that	PRON
dpc-4237	49	9	regulates	regulate	VERB
dpc-4237	49	10	tj	tj	NOUN
dpc-4237	49	11	,	,	PUNCT
dpc-4237	49	12	which	which	PRON
dpc-4237	49	13	was	be	AUX
dpc-4237	49	14	subsequently	subsequently	ADV
dpc-4237	49	15	named	name	VERB
dpc-4237	49	16	zonulin	zonulin	PROPN
dpc-4237	49	17	.	.	PUNCT
dpc-4237	50	1	proteomics	proteomic	NOUN
dpc-4237	50	2	analysis	analysis	NOUN
dpc-4237	50	3	of	of	ADP
dpc-4237	50	4	human	human	ADJ
dpc-4237	50	5	serum	serum	NOUN
dpc-4237	50	6	revealed	reveal	VERB
dpc-4237	50	7	that	that	SCONJ
dpc-4237	50	8	zonulin	zonulin	PROPN
dpc-4237	50	9	is	be	AUX
dpc-4237	50	10	pre	pre	ADJ
dpc-4237	50	11	-	-	ADJ
dpc-4237	50	12	hp2	hp2	PROPN
dpc-4237	50	13	,	,	PUNCT
dpc-4237	50	14	the	the	DET
dpc-4237	50	15	precursor	precursor	NOUN
dpc-4237	50	16	of	of	ADP
dpc-4237	50	17	haptoglobin	haptoglobin	NOUN
dpc-4237	50	18	(	(	PUNCT
dpc-4237	50	19	hp	hp	PROPN
dpc-4237	50	20	)	)	PUNCT
dpc-4237	51	1	[	[	X
dpc-4237	51	2	10	10	NUM
dpc-4237	51	3	]	]	PUNCT
dpc-4237	51	4	.	.	PUNCT
dpc-4237	52	1	pre	pre	PROPN
dpc-4237	52	2	-	-	PROPN
dpc-4237	52	3	hp2	hp2	PROPN
dpc-4237	52	4	,	,	PUNCT
dpc-4237	52	5	identified	identify	VERB
dpc-4237	52	6	as	as	ADP
dpc-4237	52	7	zonulin	zonulin	PROPN
dpc-4237	52	8	,	,	PUNCT
dpc-4237	52	9	has	have	AUX
dpc-4237	52	10	been	be	AUX
dpc-4237	52	11	shown	show	VERB
dpc-4237	52	12	to	to	PART
dpc-4237	52	13	increase	increase	VERB
dpc-4237	52	14	permeability	permeability	NOUN
dpc-4237	52	15	in	in	ADP
dpc-4237	52	16	the	the	DET
dpc-4237	52	17	jejunum	jejunum	NOUN
dpc-4237	52	18	and	and	CCONJ
dpc-4237	52	19	ileum	ileum	NOUN
dpc-4237	52	20	in	in	ADP
dpc-4237	52	21	ex	ex	PRON
dpc-4237	52	22	vivo	vivo	NOUN
dpc-4237	52	23	studies	study	NOUN
dpc-4237	52	24	.	.	PUNCT
dpc-4237	53	1	zonulin	zonulin	PROPN
dpc-4237	53	2	also	also	ADV
dpc-4237	53	3	prevents	prevent	VERB
dpc-4237	53	4	microorganism	microorganism	NOUN
dpc-4237	53	5	colonization	colonization	NOUN
dpc-4237	53	6	of	of	ADP
dpc-4237	53	7	the	the	DET
dpc-4237	53	8	small	small	ADJ
dpc-4237	53	9	intestine	intestine	NOUN
dpc-4237	53	10	by	by	ADP
dpc-4237	53	11	increasing	increase	VERB
dpc-4237	53	12	permeability	permeability	NOUN
dpc-4237	53	13	,	,	PUNCT
dpc-4237	53	14	playing	play	VERB
dpc-4237	53	15	a	a	DET
dpc-4237	53	16	role	role	NOUN
dpc-4237	53	17	in	in	ADP
dpc-4237	53	18	natural	natural	ADJ
dpc-4237	53	19	immunity	immunity	NOUN
dpc-4237	53	20	defense	defense	NOUN
dpc-4237	53	21	mechanisms	mechanism	NOUN
dpc-4237	53	22	[	[	X
dpc-4237	53	23	11	11	NUM
dpc-4237	53	24	]	]	PUNCT
dpc-4237	53	25	.	.	PUNCT
dpc-4237	54	1	elevated	elevated	ADJ
dpc-4237	54	2	zonulin	zonulin	PROPN
dpc-4237	54	3	levels	level	NOUN
dpc-4237	54	4	have	have	AUX
dpc-4237	54	5	been	be	AUX
dpc-4237	54	6	observed	observe	VERB
dpc-4237	54	7	in	in	ADP
dpc-4237	54	8	autoimmune	autoimmune	ADJ
dpc-4237	54	9	diseases	disease	NOUN
dpc-4237	54	10	such	such	ADJ
dpc-4237	54	11	as	as	ADP
dpc-4237	54	12	type	type	NOUN
dpc-4237	54	13	1	1	NUM
dpc-4237	54	14	diabetes	diabetes	NOUN
dpc-4237	54	15	mellitus	mellitus	NOUN
dpc-4237	54	16	,	,	PUNCT
dpc-4237	54	17	multiple	multiple	ADJ
dpc-4237	54	18	sclerosis	sclerosis	NOUN
dpc-4237	54	19	,	,	PUNCT
dpc-4237	54	20	inflammatory	inflammatory	ADJ
dpc-4237	54	21	bowel	bowel	NOUN
dpc-4237	54	22	diseases	disease	NOUN
dpc-4237	54	23	,	,	PUNCT
dpc-4237	54	24	and	and	CCONJ
dpc-4237	54	25	celiac	celiac	ADJ
dpc-4237	54	26	disease	disease	NOUN
dpc-4237	54	27	,	,	PUNCT
dpc-4237	54	28	in	in	ADP
dpc-4237	54	29	metabolic	metabolic	NOUN
dpc-4237	54	30	diseases	disease	NOUN
dpc-4237	54	31	like	like	ADP
dpc-4237	54	32	insulin	insulin	NOUN
dpc-4237	54	33	resistance	resistance	NOUN
dpc-4237	54	34	,	,	PUNCT
dpc-4237	54	35	type	type	NOUN
dpc-4237	54	36	2	2	NUM
dpc-4237	54	37	diabetes	diabetes	NOUN
dpc-4237	54	38	mellitus	mellitus	NOUN
dpc-4237	54	39	,	,	PUNCT
dpc-4237	54	40	polycystic	polycystic	ADJ
dpc-4237	54	41	ovary	ovary	ADJ
dpc-4237	54	42	syndrome	syndrome	NOUN
dpc-4237	54	43	,	,	PUNCT
dpc-4237	54	44	and	and	CCONJ
dpc-4237	54	45	in	in	ADP
dpc-4237	54	46	systemic	systemic	ADJ
dpc-4237	54	47	infectious	infectious	ADJ
dpc-4237	54	48	diseases	disease	NOUN
dpc-4237	54	49	such	such	ADJ
dpc-4237	54	50	as	as	ADP
dpc-4237	54	51	sepsis	sepsis	NOUN
dpc-4237	54	52	,	,	PUNCT
dpc-4237	54	53	hiv	hiv	PROPN
dpc-4237	54	54	,	,	PUNCT
dpc-4237	54	55	and	and	CCONJ
dpc-4237	54	56	intestinal	intestinal	ADJ
dpc-4237	54	57	diseases	disease	NOUN
dpc-4237	54	58	like	like	ADP
dpc-4237	54	59	irritable	irritable	ADJ
dpc-4237	54	60	bowel	bowel	NOUN
dpc-4237	54	61	syndrome	syndrome	NOUN
dpc-4237	54	62	and	and	CCONJ
dpc-4237	54	63	non	non	ADJ
dpc-4237	54	64	-	-	ADJ
dpc-4237	54	65	celiac	celiac	ADJ
dpc-4237	54	66	gluten	gluten	VERB
dpc-4237	54	67	sensitivity	sensitivity	NOUN
dpc-4237	54	68	[	[	X
dpc-4237	54	69	8	8	NUM
dpc-4237	54	70	]	]	PUNCT
dpc-4237	54	71	.	.	PUNCT
dpc-4237	55	1	objective	objective	ADJ
dpc-4237	55	2	our	our	PRON
dpc-4237	55	3	objective	objective	NOUN
dpc-4237	55	4	was	be	AUX
dpc-4237	55	5	to	to	PART
dpc-4237	55	6	evaluate	evaluate	VERB
dpc-4237	55	7	the	the	DET
dpc-4237	55	8	contribution	contribution	NOUN
dpc-4237	55	9	of	of	ADP
dpc-4237	55	10	intestinal	intestinal	ADJ
dpc-4237	55	11	permeability	permeability	NOUN
dpc-4237	55	12	to	to	ADP
dpc-4237	55	13	the	the	DET
dpc-4237	55	14	etiopathogenesis	etiopathogenesis	NOUN
dpc-4237	55	15	of	of	ADP
dpc-4237	55	16	chronic	chronic	ADJ
dpc-4237	55	17	spontaneous	spontaneous	ADJ
dpc-4237	55	18	urticaria	urticaria	NOUN
dpc-4237	55	19	(	(	PUNCT
dpc-4237	55	20	csu	csu	PROPN
dpc-4237	55	21	)	)	PUNCT
dpc-4237	55	22	and	and	CCONJ
dpc-4237	55	23	to	to	PART
dpc-4237	55	24	investigate	investigate	VERB
dpc-4237	55	25	its	its	PRON
dpc-4237	55	26	correlation	correlation	NOUN
dpc-4237	55	27	with	with	ADP
dpc-4237	55	28	disease	disease	NOUN
dpc-4237	55	29	severity	severity	NOUN
dpc-4237	55	30	.	.	PUNCT
dpc-4237	56	1	this	this	DET
dpc-4237	56	2	study	study	NOUN
dpc-4237	56	3	aimed	aim	VERB
dpc-4237	56	4	to	to	PART
dpc-4237	56	5	fill	fill	VERB
dpc-4237	56	6	a	a	DET
dpc-4237	56	7	gap	gap	NOUN
dpc-4237	56	8	in	in	ADP
dpc-4237	56	9	the	the	DET
dpc-4237	56	10	existing	exist	VERB
dpc-4237	56	11	literature	literature	NOUN
dpc-4237	56	12	and	and	CCONJ
dpc-4237	56	13	provide	provide	VERB
dpc-4237	56	14	new	new	ADJ
dpc-4237	56	15	insights	insight	NOUN
dpc-4237	56	16	into	into	ADP
dpc-4237	56	17	the	the	DET
dpc-4237	56	18	underlying	underlie	VERB
dpc-4237	56	19	mechanisms	mechanism	NOUN
dpc-4237	56	20	of	of	ADP
dpc-4237	56	21	csu	csu	PROPN
dpc-4237	56	22	.	.	PUNCT
dpc-4237	57	1	methods	method	NOUN
dpc-4237	57	2	study	study	VERB
dpc-4237	57	3	design	design	NOUN
dpc-4237	57	4	and	and	CCONJ
dpc-4237	57	5	participants	participant	NOUN
dpc-4237	57	6	this	this	DET
dpc-4237	57	7	study	study	NOUN
dpc-4237	57	8	was	be	AUX
dpc-4237	57	9	conducted	conduct	VERB
dpc-4237	57	10	at	at	ADP
dpc-4237	57	11	the	the	DET
dpc-4237	57	12	dermatology	dermatology	NOUN
dpc-4237	57	13	department	department	NOUN
dpc-4237	57	14	of	of	ADP
dpc-4237	57	15	the	the	DET
dpc-4237	57	16	hospital	hospital	NOUN
dpc-4237	57	17	from	from	ADP
dpc-4237	57	18	april	april	PROPN
dpc-4237	57	19	2021	2021	NUM
dpc-4237	57	20	to	to	ADP
dpc-4237	57	21	december	december	PROPN
dpc-4237	57	22	2021	2021	NUM
dpc-4237	57	23	.	.	PUNCT
dpc-4237	58	1	it	it	PRON
dpc-4237	58	2	was	be	AUX
dpc-4237	58	3	approved	approve	VERB
dpc-4237	58	4	by	by	ADP
dpc-4237	58	5	the	the	DET
dpc-4237	58	6	non	non	ADJ
dpc-4237	58	7	-	-	ADJ
dpc-4237	58	8	interventional	interventional	ADJ
dpc-4237	58	9	clinical	clinical	ADJ
dpc-4237	58	10	research	research	NOUN
dpc-4237	58	11	ethics	ethic	NOUN
dpc-4237	58	12	board	board	NOUN
dpc-4237	58	13	of	of	ADP
dpc-4237	58	14	the	the	DET
dpc-4237	58	15	hospital	hospital	NOUN
dpc-4237	58	16	in	in	ADP
dpc-4237	58	17	accordance	accordance	NOUN
dpc-4237	58	18	with	with	ADP
dpc-4237	58	19	the	the	DET
dpc-4237	58	20	declaration	declaration	NOUN
dpc-4237	58	21	of	of	ADP
dpc-4237	58	22	helsinki	helsinki	PROPN
dpc-4237	58	23	principles	principle	NOUN
dpc-4237	58	24	[	[	X
dpc-4237	58	25	08.02.2021	08.02.2021	X
dpc-4237	58	26	,	,	PUNCT
dpc-4237	58	27	go	go	VERB
dpc-4237	58	28	104/01	104/01	NUM
dpc-4237	58	29	]	]	PUNCT
dpc-4237	58	30	.	.	PUNCT
dpc-4237	59	1	written	write	VERB
dpc-4237	59	2	informed	informed	ADJ
dpc-4237	59	3	consent	consent	NOUN
dpc-4237	59	4	was	be	AUX
dpc-4237	59	5	obtained	obtain	VERB
dpc-4237	59	6	from	from	ADP
dpc-4237	59	7	all	all	DET
dpc-4237	59	8	participants	participant	NOUN
dpc-4237	59	9	before	before	ADP
dpc-4237	59	10	enrollment	enrollment	NOUN
dpc-4237	59	11	.	.	PUNCT
dpc-4237	60	1	we	we	PRON
dpc-4237	60	2	recruited	recruit	VERB
dpc-4237	60	3	122	122	NUM
dpc-4237	60	4	participants	participant	NOUN
dpc-4237	60	5	,	,	PUNCT
dpc-4237	60	6	including	include	VERB
dpc-4237	60	7	63	63	NUM
dpc-4237	60	8	patients	patient	NOUN
dpc-4237	60	9	with	with	ADP
dpc-4237	60	10	csu	csu	PROPN
dpc-4237	60	11	(	(	PUNCT
dpc-4237	60	12	30	30	NUM
dpc-4237	60	13	males	male	NOUN
dpc-4237	60	14	and	and	CCONJ
dpc-4237	60	15	33	33	NUM
dpc-4237	60	16	females	female	NOUN
dpc-4237	60	17	aged	age	VERB
dpc-4237	60	18	18–62	18–62	NUM
dpc-4237	60	19	years	year	NOUN
dpc-4237	60	20	,	,	PUNCT
dpc-4237	60	21	with	with	ADP
dpc-4237	60	22	an	an	DET
dpc-4237	60	23	average	average	ADJ
dpc-4237	60	24	age	age	NOUN
dpc-4237	60	25	of	of	ADP
dpc-4237	60	26	32.96	32.96	NUM
dpc-4237	60	27	)	)	PUNCT
dpc-4237	60	28	and	and	CCONJ
dpc-4237	60	29	59	59	NUM
dpc-4237	60	30	ageand	ageand	NOUN
dpc-4237	60	31	sex	sex	NOUN
dpc-4237	60	32	-	-	PUNCT
dpc-4237	60	33	matched	match	VERB
dpc-4237	60	34	healthy	healthy	ADJ
dpc-4237	60	35	controls	control	NOUN
dpc-4237	60	36	without	without	ADP
dpc-4237	60	37	csu	csu	PROPN
dpc-4237	60	38	or	or	CCONJ
dpc-4237	60	39	other	other	ADJ
dpc-4237	60	40	skin	skin	NOUN
dpc-4237	60	41	diseases	disease	NOUN
dpc-4237	60	42	.	.	PUNCT
dpc-4237	61	1	based	base	VERB
dpc-4237	61	2	on	on	ADP
dpc-4237	61	3	a	a	DET
dpc-4237	61	4	power	power	NOUN
dpc-4237	61	5	analysis	analysis	NOUN
dpc-4237	61	6	using	use	VERB
dpc-4237	61	7	the	the	DET
dpc-4237	61	8	g*power	g*power	PROPN
dpc-4237	61	9	3.1.9.2	3.1.9.2	NUM
dpc-4237	61	10	program	program	NOUN
dpc-4237	61	11	,	,	PUNCT
dpc-4237	61	12	a	a	DET
dpc-4237	61	13	total	total	NOUN
dpc-4237	61	14	of	of	ADP
dpc-4237	61	15	at	at	ADV
dpc-4237	61	16	least	least	ADV
dpc-4237	61	17	120	120	NUM
dpc-4237	61	18	samples	sample	NOUN
dpc-4237	61	19	was	be	AUX
dpc-4237	61	20	determined	determine	VERB
dpc-4237	61	21	to	to	PART
dpc-4237	61	22	be	be	AUX
dpc-4237	61	23	sufficient	sufficient	ADJ
dpc-4237	61	24	,	,	PUNCT
dpc-4237	61	25	with	with	ADP
dpc-4237	61	26	an	an	DET
dpc-4237	61	27	effect	effect	NOUN
dpc-4237	61	28	size	size	NOUN
dpc-4237	61	29	of	of	ADP
dpc-4237	61	30	80	80	NUM
dpc-4237	61	31	%	%	NOUN
dpc-4237	61	32	power	power	NOUN
dpc-4237	61	33	,	,	PUNCT
dpc-4237	61	34	a	a	DET
dpc-4237	61	35	5	5	NUM
dpc-4237	61	36	%	%	NOUN
dpc-4237	61	37	margin	margin	NOUN
dpc-4237	61	38	of	of	ADP
dpc-4237	61	39	error	error	NOUN
dpc-4237	61	40	,	,	PUNCT
dpc-4237	61	41	and	and	CCONJ
dpc-4237	61	42	conclusion	conclusion	NOUN
dpc-4237	61	43	:	:	PUNCT
dpc-4237	61	44	the	the	DET
dpc-4237	61	45	observed	observe	VERB
dpc-4237	61	46	results	result	NOUN
dpc-4237	61	47	suggest	suggest	VERB
dpc-4237	61	48	that	that	SCONJ
dpc-4237	61	49	increased	increase	VERB
dpc-4237	61	50	intestinal	intestinal	ADJ
dpc-4237	61	51	permeability	permeability	NOUN
dpc-4237	61	52	,	,	PUNCT
dpc-4237	61	53	as	as	SCONJ
dpc-4237	61	54	indicated	indicate	VERB
dpc-4237	61	55	by	by	ADP
dpc-4237	61	56	elevated	elevated	ADJ
dpc-4237	61	57	zonulin	zonulin	PROPN
dpc-4237	61	58	levels	level	NOUN
dpc-4237	61	59	,	,	PUNCT
dpc-4237	61	60	may	may	AUX
dpc-4237	61	61	play	play	VERB
dpc-4237	61	62	a	a	DET
dpc-4237	61	63	crucial	crucial	ADJ
dpc-4237	61	64	role	role	NOUN
dpc-4237	61	65	in	in	ADP
dpc-4237	61	66	the	the	DET
dpc-4237	61	67	pathophysiology	pathophysiology	NOUN
dpc-4237	61	68	of	of	ADP
dpc-4237	61	69	both	both	DET
dpc-4237	61	70	csu	csu	NOUN
dpc-4237	61	71	and	and	CCONJ
dpc-4237	61	72	angioedema	angioedema	VERB
dpc-4237	61	73	.	.	PUNCT
dpc-4237	62	1	this	this	DET
dpc-4237	62	2	association	association	NOUN
dpc-4237	62	3	highlights	highlight	VERB
dpc-4237	62	4	the	the	DET
dpc-4237	62	5	potential	potential	ADJ
dpc-4237	62	6	significance	significance	NOUN
dpc-4237	62	7	of	of	ADP
dpc-4237	62	8	intestinal	intestinal	ADJ
dpc-4237	62	9	permeability	permeability	NOUN
dpc-4237	62	10	in	in	ADP
dpc-4237	62	11	the	the	DET
dpc-4237	62	12	development	development	NOUN
dpc-4237	62	13	and	and	CCONJ
dpc-4237	62	14	manifestation	manifestation	NOUN
dpc-4237	62	15	of	of	ADP
dpc-4237	62	16	these	these	DET
dpc-4237	62	17	conditions	condition	NOUN
dpc-4237	62	18	.	.	PUNCT
dpc-4237	63	1	original	original	ADJ
dpc-4237	63	2	article	article	NOUN
dpc-4237	63	3	|	|	ADV
dpc-4237	63	4	dermatol	dermatol	ADJ
dpc-4237	63	5	pract	pract	NOUN
dpc-4237	63	6	concept	concept	NOUN
dpc-4237	63	7	.	.	PUNCT
dpc-4237	64	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	64	2	3	3	NUM
dpc-4237	64	3	d=0.496	d=0.496	NOUN
dpc-4237	64	4	.	.	PUNCT
dpc-4237	65	1	all	all	DET
dpc-4237	65	2	participants	participant	NOUN
dpc-4237	65	3	were	be	AUX
dpc-4237	65	4	turkish	turkish	ADJ
dpc-4237	65	5	and	and	CCONJ
dpc-4237	65	6	residents	resident	NOUN
dpc-4237	65	7	of	of	ADP
dpc-4237	65	8	ankara	ankara	PROPN
dpc-4237	65	9	,	,	PUNCT
dpc-4237	65	10	turkey	turkey	PROPN
dpc-4237	65	11	.	.	PUNCT
dpc-4237	66	1	the	the	DET
dpc-4237	66	2	diagnosis	diagnosis	NOUN
dpc-4237	66	3	of	of	ADP
dpc-4237	66	4	csu	csu	PROPN
dpc-4237	66	5	was	be	AUX
dpc-4237	66	6	based	base	VERB
dpc-4237	66	7	on	on	ADP
dpc-4237	66	8	clinical	clinical	ADJ
dpc-4237	66	9	criteria	criterion	NOUN
dpc-4237	66	10	.	.	PUNCT
dpc-4237	67	1	patients	patient	NOUN
dpc-4237	67	2	who	who	PRON
dpc-4237	67	3	presented	present	VERB
dpc-4237	67	4	to	to	ADP
dpc-4237	67	5	the	the	DET
dpc-4237	67	6	hospital	hospital	NOUN
dpc-4237	67	7	and	and	CCONJ
dpc-4237	67	8	volunteered	volunteer	VERB
dpc-4237	67	9	to	to	PART
dpc-4237	67	10	participate	participate	VERB
dpc-4237	67	11	in	in	ADP
dpc-4237	67	12	the	the	DET
dpc-4237	67	13	study	study	NOUN
dpc-4237	67	14	were	be	AUX
dpc-4237	67	15	included	include	VERB
dpc-4237	67	16	.	.	PUNCT
dpc-4237	68	1	exclusion	exclusion	NOUN
dpc-4237	68	2	criteria	criterion	NOUN
dpc-4237	68	3	for	for	ADP
dpc-4237	68	4	csu	csu	PROPN
dpc-4237	68	5	patients	patient	NOUN
dpc-4237	68	6	included	include	VERB
dpc-4237	68	7	being	be	AUX
dpc-4237	68	8	younger	young	ADJ
dpc-4237	68	9	than	than	ADP
dpc-4237	68	10	18	18	NUM
dpc-4237	68	11	or	or	CCONJ
dpc-4237	68	12	older	old	ADJ
dpc-4237	68	13	than	than	ADP
dpc-4237	68	14	65	65	NUM
dpc-4237	68	15	,	,	PUNCT
dpc-4237	68	16	using	use	VERB
dpc-4237	68	17	systemic	systemic	ADJ
dpc-4237	68	18	antibiotic	antibiotic	ADJ
dpc-4237	68	19	therapy	therapy	NOUN
dpc-4237	68	20	,	,	PUNCT
dpc-4237	68	21	being	be	AUX
dpc-4237	68	22	obese	obese	ADJ
dpc-4237	68	23	,	,	PUNCT
dpc-4237	68	24	or	or	CCONJ
dpc-4237	68	25	having	have	VERB
dpc-4237	68	26	concomitant	concomitant	ADJ
dpc-4237	68	27	systemic	systemic	ADJ
dpc-4237	68	28	inflammatory	inflammatory	ADJ
dpc-4237	68	29	diseases	disease	NOUN
dpc-4237	68	30	,	,	PUNCT
dpc-4237	68	31	autoimmune	autoimmune	ADJ
dpc-4237	68	32	diseases	disease	NOUN
dpc-4237	68	33	,	,	PUNCT
dpc-4237	68	34	current	current	ADJ
dpc-4237	68	35	infections	infection	NOUN
dpc-4237	68	36	,	,	PUNCT
dpc-4237	68	37	or	or	CCONJ
dpc-4237	68	38	previous	previous	ADJ
dpc-4237	68	39	gastrointestinal	gastrointestinal	ADJ
dpc-4237	68	40	tract	tract	NOUN
dpc-4237	68	41	diseases	disease	NOUN
dpc-4237	68	42	.	.	PUNCT
dpc-4237	69	1	the	the	DET
dpc-4237	69	2	control	control	PROPN
dpc-4237	69	3	group	group	NOUN
dpc-4237	69	4	consisted	consist	VERB
dpc-4237	69	5	of	of	ADP
dpc-4237	69	6	ageand	ageand	NOUN
dpc-4237	69	7	sex	sex	NOUN
dpc-4237	69	8	-	-	PUNCT
dpc-4237	69	9	matched	match	VERB
dpc-4237	69	10	healthy	healthy	ADJ
dpc-4237	69	11	subjects	subject	NOUN
dpc-4237	69	12	who	who	PRON
dpc-4237	69	13	met	meet	VERB
dpc-4237	69	14	the	the	DET
dpc-4237	69	15	same	same	ADJ
dpc-4237	69	16	inclusion	inclusion	NOUN
dpc-4237	69	17	and	and	CCONJ
dpc-4237	69	18	exclusion	exclusion	NOUN
dpc-4237	69	19	criteria	criterion	NOUN
dpc-4237	69	20	as	as	ADP
dpc-4237	69	21	the	the	DET
dpc-4237	69	22	csu	csu	PROPN
dpc-4237	69	23	patients	patient	NOUN
dpc-4237	69	24	.	.	PUNCT
dpc-4237	70	1	measures	measure	NOUN
dpc-4237	70	2	patients	patient	NOUN
dpc-4237	70	3	had	have	VERB
dpc-4237	70	4	their	their	PRON
dpc-4237	70	5	age	age	NOUN
dpc-4237	70	6	,	,	PUNCT
dpc-4237	70	7	weight	weight	NOUN
dpc-4237	70	8	,	,	PUNCT
dpc-4237	70	9	sex	sex	NOUN
dpc-4237	70	10	,	,	PUNCT
dpc-4237	70	11	marital	marital	ADJ
dpc-4237	70	12	status	status	NOUN
dpc-4237	70	13	,	,	PUNCT
dpc-4237	70	14	past	past	ADP
dpc-4237	70	15	medical	medical	ADJ
dpc-4237	70	16	history	history	NOUN
dpc-4237	70	17	,	,	PUNCT
dpc-4237	70	18	and	and	CCONJ
dpc-4237	70	19	self	self	NOUN
dpc-4237	70	20	-	-	PUNCT
dpc-4237	70	21	report	report	NOUN
dpc-4237	70	22	documented	document	VERB
dpc-4237	70	23	.	.	PUNCT
dpc-4237	71	1	questions	question	NOUN
dpc-4237	71	2	were	be	AUX
dpc-4237	71	3	asked	ask	VERB
dpc-4237	71	4	about	about	ADP
dpc-4237	71	5	the	the	DET
dpc-4237	71	6	onset	onset	NOUN
dpc-4237	71	7	of	of	ADP
dpc-4237	71	8	their	their	PRON
dpc-4237	71	9	illnesses	illness	NOUN
dpc-4237	71	10	,	,	PUNCT
dpc-4237	71	11	the	the	DET
dpc-4237	71	12	duration	duration	NOUN
dpc-4237	71	13	of	of	ADP
dpc-4237	71	14	their	their	PRON
dpc-4237	71	15	attacks	attack	NOUN
dpc-4237	71	16	,	,	PUNCT
dpc-4237	71	17	and	and	CCONJ
dpc-4237	71	18	whether	whether	SCONJ
dpc-4237	71	19	angioedema	angioedema	ADV
dpc-4237	71	20	coexisted	coexist	VERB
dpc-4237	71	21	with	with	ADP
dpc-4237	71	22	them	they	PRON
dpc-4237	71	23	.	.	PUNCT
dpc-4237	72	1	based	base	VERB
dpc-4237	72	2	on	on	ADP
dpc-4237	72	3	their	their	PRON
dpc-4237	72	4	urticaria	urticaria	NOUN
dpc-4237	72	5	activity	activity	NOUN
dpc-4237	72	6	score	score	NOUN
dpc-4237	72	7	,	,	PUNCT
dpc-4237	72	8	patients	patient	NOUN
dpc-4237	72	9	were	be	AUX
dpc-4237	72	10	categorized	categorize	VERB
dpc-4237	72	11	as	as	ADP
dpc-4237	72	12	having	have	VERB
dpc-4237	72	13	mild	mild	ADJ
dpc-4237	72	14	,	,	PUNCT
dpc-4237	72	15	moderate	moderate	ADJ
dpc-4237	72	16	,	,	PUNCT
dpc-4237	72	17	or	or	CCONJ
dpc-4237	72	18	severe	severe	ADJ
dpc-4237	72	19	urticaria	urticaria	NOUN
dpc-4237	72	20	.	.	PUNCT
dpc-4237	73	1	the	the	DET
dpc-4237	73	2	weekly	weekly	ADJ
dpc-4237	73	3	itch	itch	NOUN
dpc-4237	73	4	severity	severity	NOUN
dpc-4237	73	5	score	score	NOUN
dpc-4237	73	6	and	and	CCONJ
dpc-4237	73	7	the	the	DET
dpc-4237	73	8	weekly	weekly	ADJ
dpc-4237	73	9	hives	hive	NOUN
dpc-4237	73	10	severity	severity	NOUN
dpc-4237	73	11	score	score	NOUN
dpc-4237	73	12	,	,	PUNCT
dpc-4237	73	13	score	score	NOUN
dpc-4237	73	14	range	range	NOUN
dpc-4237	73	15	of	of	ADP
dpc-4237	73	16	0	0	NUM
dpc-4237	73	17	to	to	PART
dpc-4237	73	18	21	21	NUM
dpc-4237	73	19	,	,	PUNCT
dpc-4237	73	20	are	be	AUX
dpc-4237	73	21	two	two	NUM
dpc-4237	73	22	validated	validate	VERB
dpc-4237	73	23	patient	patient	NOUN
dpc-4237	73	24	reported	report	VERB
dpc-4237	73	25	outcomes	outcome	NOUN
dpc-4237	73	26	measured	measure	VERB
dpc-4237	73	27	by	by	ADP
dpc-4237	73	28	the	the	DET
dpc-4237	73	29	urticaria	urticaria	NOUN
dpc-4237	73	30	activity	activity	NOUN
dpc-4237	73	31	score	score	NOUN
dpc-4237	73	32	(	(	PUNCT
dpc-4237	73	33	uas7	uas7	ADJ
dpc-4237	73	34	)	)	PUNCT
dpc-4237	73	35	.	.	PUNCT
dpc-4237	74	1	uas7	uas7	PROPN
dpc-4237	74	2	total	total	VERB
dpc-4237	74	3	scores	score	NOUN
dpc-4237	74	4	range	range	VERB
dpc-4237	74	5	from	from	ADP
dpc-4237	74	6	0	0	NUM
dpc-4237	74	7	to	to	ADP
dpc-4237	74	8	42	42	NUM
dpc-4237	74	9	,	,	PUNCT
dpc-4237	74	10	with	with	ADP
dpc-4237	74	11	lower	low	ADJ
dpc-4237	74	12	scores	score	NOUN
dpc-4237	74	13	representing	represent	VERB
dpc-4237	74	14	fewer	few	ADJ
dpc-4237	74	15	symptoms	symptom	NOUN
dpc-4237	74	16	.	.	PUNCT
dpc-4237	75	1	uas7	uas7	PROPN
dpc-4237	75	2	score	score	VERB
dpc-4237	75	3	≤6	≤6	PROPN
dpc-4237	75	4	is	be	AUX
dpc-4237	75	5	well	well	ADV
dpc-4237	75	6	controlled	control	VERB
dpc-4237	75	7	,	,	PUNCT
dpc-4237	75	8	7	7	NUM
dpc-4237	75	9	-	-	SYM
dpc-4237	75	10	15	15	NUM
dpc-4237	75	11	is	be	AUX
dpc-4237	75	12	mild	mild	ADJ
dpc-4237	75	13	,	,	PUNCT
dpc-4237	75	14	16	16	NUM
dpc-4237	75	15	-	-	SYM
dpc-4237	75	16	27	27	NUM
dpc-4237	75	17	is	be	AUX
dpc-4237	75	18	moderate	moderate	ADJ
dpc-4237	75	19	,	,	PUNCT
dpc-4237	75	20	and	and	CCONJ
dpc-4237	75	21	28	28	NUM
dpc-4237	75	22	-	-	SYM
dpc-4237	75	23	42	42	NUM
dpc-4237	75	24	can	can	AUX
dpc-4237	75	25	be	be	AUX
dpc-4237	75	26	considered	consider	VERB
dpc-4237	75	27	as	as	ADP
dpc-4237	75	28	severe	severe	ADJ
dpc-4237	75	29	urticaria	urticaria	NOUN
dpc-4237	75	30	.	.	PUNCT
dpc-4237	76	1	sample	sample	NOUN
dpc-4237	76	2	collection	collection	NOUN
dpc-4237	76	3	,	,	PUNCT
dpc-4237	76	4	biochemical	biochemical	ADJ
dpc-4237	76	5	and	and	CCONJ
dpc-4237	76	6	molecular	molecular	ADJ
dpc-4237	76	7	analysis	analysis	NOUN
dpc-4237	76	8	all	all	DET
dpc-4237	76	9	participants	participant	NOUN
dpc-4237	76	10	had	have	VERB
dpc-4237	76	11	venous	venous	ADJ
dpc-4237	76	12	blood	blood	NOUN
dpc-4237	76	13	samples	sample	NOUN
dpc-4237	76	14	taken	take	VERB
dpc-4237	76	15	,	,	PUNCT
dpc-4237	76	16	which	which	PRON
dpc-4237	76	17	were	be	AUX
dpc-4237	76	18	sent	send	VERB
dpc-4237	76	19	to	to	ADP
dpc-4237	76	20	the	the	DET
dpc-4237	76	21	biochemistry	biochemistry	NOUN
dpc-4237	76	22	lab	lab	NOUN
dpc-4237	76	23	within	within	ADP
dpc-4237	76	24	no	no	DET
dpc-4237	76	25	more	more	ADJ
dpc-4237	76	26	than	than	ADP
dpc-4237	76	27	two	two	NUM
dpc-4237	76	28	hours	hour	NOUN
dpc-4237	76	29	.	.	PUNCT
dpc-4237	77	1	samples	sample	NOUN
dpc-4237	77	2	were	be	AUX
dpc-4237	77	3	centrifuged	centrifuge	VERB
dpc-4237	77	4	for	for	ADP
dpc-4237	77	5	10	10	NUM
dpc-4237	77	6	minutes	minute	NOUN
dpc-4237	77	7	at	at	ADP
dpc-4237	77	8	3000	3000	NUM
dpc-4237	77	9	rpm	rpm	NOUN
dpc-4237	77	10	.	.	PUNCT
dpc-4237	78	1	serum	serum	NOUN
dpc-4237	78	2	samples	sample	NOUN
dpc-4237	78	3	were	be	AUX
dpc-4237	78	4	then	then	ADV
dpc-4237	78	5	separated	separate	VERB
dpc-4237	78	6	into	into	ADP
dpc-4237	78	7	individual	individual	ADJ
dpc-4237	78	8	eppendorf	eppendorf	PROPN
dpc-4237	78	9	tubes	tube	NOUN
dpc-4237	78	10	and	and	CCONJ
dpc-4237	78	11	kept	keep	VERB
dpc-4237	78	12	at	at	ADP
dpc-4237	78	13	-80	-80	NOUN
dpc-4237	78	14	°	°	ADP
dpc-4237	78	15	c	c	NOUN
dpc-4237	78	16	until	until	ADP
dpc-4237	78	17	the	the	DET
dpc-4237	78	18	analysis	analysis	NOUN
dpc-4237	78	19	day	day	NOUN
dpc-4237	78	20	.	.	PUNCT
dpc-4237	79	1	serum	serum	NOUN
dpc-4237	79	2	samples	sample	NOUN
dpc-4237	79	3	were	be	AUX
dpc-4237	79	4	extracted	extract	VERB
dpc-4237	79	5	on	on	ADP
dpc-4237	79	6	the	the	DET
dpc-4237	79	7	day	day	NOUN
dpc-4237	79	8	of	of	ADP
dpc-4237	79	9	analysis	analysis	NOUN
dpc-4237	79	10	according	accord	VERB
dpc-4237	79	11	to	to	ADP
dpc-4237	79	12	the	the	DET
dpc-4237	79	13	manufacturer	manufacturer	NOUN
dpc-4237	79	14	’s	’s	PART
dpc-4237	79	15	instructions	instruction	NOUN
dpc-4237	79	16	and	and	CCONJ
dpc-4237	79	17	stored	store	VERB
dpc-4237	79	18	for	for	ADP
dpc-4237	79	19	30	30	NUM
dpc-4237	79	20	minutes	minute	NOUN
dpc-4237	79	21	at	at	ADP
dpc-4237	79	22	room	room	NOUN
dpc-4237	79	23	temperature	temperature	NOUN
dpc-4237	79	24	(	(	PUNCT
dpc-4237	79	25	18	18	NUM
dpc-4237	79	26	°	°	PROPN
dpc-4237	79	27	c–25	c–25	ADP
dpc-4237	79	28	°	°	NOUN
dpc-4237	79	29	c	c	NOUN
dpc-4237	79	30	)	)	PUNCT
dpc-4237	79	31	.	.	PUNCT
dpc-4237	80	1	the	the	DET
dpc-4237	80	2	sandwich	sandwich	NOUN
dpc-4237	80	3	enzyme	enzyme	NOUN
dpc-4237	80	4	-	-	PUNCT
dpc-4237	80	5	linked	link	VERB
dpc-4237	80	6	immunosorbent	immunosorbent	NOUN
dpc-4237	80	7	assay	assay	NOUN
dpc-4237	80	8	(	(	PUNCT
dpc-4237	80	9	sandwich	sandwich	NOUN
dpc-4237	80	10	-	-	PUNCT
dpc-4237	80	11	elisa	elisa	NOUN
dpc-4237	80	12	,	,	PUNCT
dpc-4237	80	13	elabscience	elabscience	NOUN
dpc-4237	80	14	®	®	NOUN
dpc-4237	80	15	,	,	PUNCT
dpc-4237	80	16	catalog	catalog	NOUN
dpc-4237	80	17	number	number	NOUN
dpc-4237	80	18	:	:	PUNCT
dpc-4237	80	19	e	e	X
dpc-4237	80	20	-	-	PROPN
dpc-4237	80	21	el	el	PROPN
dpc-4237	80	22	-	-	PUNCT
dpc-4237	80	23	h5560	h5560	PROPN
dpc-4237	80	24	,	,	PUNCT
dpc-4237	80	25	wuhan	wuhan	PROPN
dpc-4237	80	26	,	,	PUNCT
dpc-4237	80	27	china	china	PROPN
dpc-4237	80	28	)	)	PUNCT
dpc-4237	80	29	kit	kit	NOUN
dpc-4237	80	30	was	be	AUX
dpc-4237	80	31	used	use	VERB
dpc-4237	80	32	in	in	ADP
dpc-4237	80	33	the	the	DET
dpc-4237	80	34	analysis	analysis	NOUN
dpc-4237	80	35	to	to	PART
dpc-4237	80	36	determine	determine	VERB
dpc-4237	80	37	the	the	DET
dpc-4237	80	38	amounts	amount	NOUN
dpc-4237	80	39	of	of	ADP
dpc-4237	80	40	human	human	ADJ
dpc-4237	80	41	zonulin	zonulin	PROPN
dpc-4237	80	42	in	in	ADP
dpc-4237	80	43	serum	serum	NOUN
dpc-4237	80	44	samples	sample	NOUN
dpc-4237	80	45	.	.	PUNCT
dpc-4237	81	1	in	in	ADP
dpc-4237	81	2	our	our	PRON
dpc-4237	81	3	study	study	NOUN
dpc-4237	81	4	,	,	PUNCT
dpc-4237	81	5	the	the	DET
dpc-4237	81	6	sensitivity	sensitivity	NOUN
dpc-4237	81	7	for	for	ADP
dpc-4237	81	8	detecting	detect	VERB
dpc-4237	81	9	chitin	chitin	NOUN
dpc-4237	81	10	was	be	AUX
dpc-4237	81	11	established	establish	VERB
dpc-4237	81	12	at	at	ADP
dpc-4237	81	13	0.47	0.47	NUM
dpc-4237	81	14	ng	ng	PROPN
dpc-4237	81	15	/	/	SYM
dpc-4237	81	16	ml	ml	PROPN
dpc-4237	81	17	.	.	PUNCT
dpc-4237	82	1	this	this	DET
dpc-4237	82	2	level	level	NOUN
dpc-4237	82	3	of	of	ADP
dpc-4237	82	4	sensitivity	sensitivity	NOUN
dpc-4237	82	5	ensures	ensure	VERB
dpc-4237	82	6	that	that	SCONJ
dpc-4237	82	7	even	even	ADV
dpc-4237	82	8	minimal	minimal	ADJ
dpc-4237	82	9	concentrations	concentration	NOUN
dpc-4237	82	10	of	of	ADP
dpc-4237	82	11	chitin	chitin	NOUN
dpc-4237	82	12	can	can	AUX
dpc-4237	82	13	be	be	AUX
dpc-4237	82	14	accurately	accurately	ADV
dpc-4237	82	15	identified	identify	VERB
dpc-4237	82	16	in	in	ADP
dpc-4237	82	17	our	our	PRON
dpc-4237	82	18	assays	assay	NOUN
dpc-4237	82	19	.	.	PUNCT
dpc-4237	83	1	regarding	regard	VERB
dpc-4237	83	2	the	the	DET
dpc-4237	83	3	precision	precision	NOUN
dpc-4237	83	4	of	of	ADP
dpc-4237	83	5	the	the	DET
dpc-4237	83	6	assay	assay	NOUN
dpc-4237	83	7	,	,	PUNCT
dpc-4237	83	8	according	accord	VERB
dpc-4237	83	9	to	to	ADP
dpc-4237	83	10	the	the	DET
dpc-4237	83	11	manufacturer	manufacturer	NOUN
dpc-4237	83	12	’s	’s	PART
dpc-4237	83	13	specifications	specification	NOUN
dpc-4237	83	14	,	,	PUNCT
dpc-4237	83	15	the	the	DET
dpc-4237	83	16	intra	intra	ADJ
dpc-4237	83	17	-	-	ADJ
dpc-4237	83	18	assay	assay	ADJ
dpc-4237	83	19	coefficient	coefficient	NOUN
dpc-4237	83	20	of	of	ADP
dpc-4237	83	21	variation	variation	NOUN
dpc-4237	83	22	(	(	PUNCT
dpc-4237	83	23	cv	cv	NOUN
dpc-4237	83	24	)	)	PUNCT
dpc-4237	83	25	ranged	range	VERB
dpc-4237	83	26	from	from	ADP
dpc-4237	83	27	4.85	4.85	NUM
dpc-4237	83	28	%	%	NOUN
dpc-4237	83	29	to	to	PART
dpc-4237	83	30	5.69	5.69	NUM
dpc-4237	83	31	%	%	NOUN
dpc-4237	83	32	.	.	PUNCT
dpc-4237	84	1	the	the	DET
dpc-4237	84	2	intra	intra	ADJ
dpc-4237	84	3	-	-	ADJ
dpc-4237	84	4	assay	assay	ADJ
dpc-4237	84	5	cv	cv	PROPN
dpc-4237	84	6	is	be	AUX
dpc-4237	84	7	a	a	DET
dpc-4237	84	8	measure	measure	NOUN
dpc-4237	84	9	of	of	ADP
dpc-4237	84	10	the	the	DET
dpc-4237	84	11	variability	variability	NOUN
dpc-4237	84	12	in	in	ADP
dpc-4237	84	13	the	the	DET
dpc-4237	84	14	assay	assay	NOUN
dpc-4237	84	15	results	result	NOUN
dpc-4237	84	16	when	when	SCONJ
dpc-4237	84	17	the	the	DET
dpc-4237	84	18	same	same	ADJ
dpc-4237	84	19	sample	sample	NOUN
dpc-4237	84	20	is	be	AUX
dpc-4237	84	21	tested	test	VERB
dpc-4237	84	22	multiple	multiple	ADJ
dpc-4237	84	23	times	time	NOUN
dpc-4237	84	24	within	within	ADP
dpc-4237	84	25	the	the	DET
dpc-4237	84	26	same	same	ADJ
dpc-4237	84	27	assay	assay	NOUN
dpc-4237	84	28	.	.	PUNCT
dpc-4237	85	1	this	this	DET
dpc-4237	85	2	level	level	NOUN
dpc-4237	85	3	of	of	ADP
dpc-4237	85	4	variation	variation	NOUN
dpc-4237	85	5	indicates	indicate	VERB
dpc-4237	85	6	a	a	DET
dpc-4237	85	7	reasonably	reasonably	ADV
dpc-4237	85	8	consistent	consistent	ADJ
dpc-4237	85	9	performance	performance	NOUN
dpc-4237	85	10	of	of	ADP
dpc-4237	85	11	the	the	DET
dpc-4237	85	12	assay	assay	NOUN
dpc-4237	85	13	for	for	ADP
dpc-4237	85	14	repeated	repeat	VERB
dpc-4237	85	15	measurements	measurement	NOUN
dpc-4237	85	16	.	.	PUNCT
dpc-4237	86	1	furthermore	furthermore	ADV
dpc-4237	86	2	,	,	PUNCT
dpc-4237	86	3	the	the	DET
dpc-4237	86	4	inter	inter	ADJ
dpc-4237	86	5	-	-	ADJ
dpc-4237	86	6	assay	assay	ADJ
dpc-4237	86	7	coefficient	coefficient	NOUN
dpc-4237	86	8	of	of	ADP
dpc-4237	86	9	variation	variation	NOUN
dpc-4237	86	10	(	(	PUNCT
dpc-4237	86	11	inter	inter	ADJ
dpc-4237	86	12	-	-	ADJ
dpc-4237	86	13	assay	assay	ADJ
dpc-4237	86	14	cv	cv	NOUN
dpc-4237	86	15	)	)	PUNCT
dpc-4237	86	16	was	be	AUX
dpc-4237	86	17	documented	document	VERB
dpc-4237	86	18	to	to	PART
dpc-4237	86	19	be	be	AUX
dpc-4237	86	20	between	between	ADP
dpc-4237	86	21	4.35	4.35	NUM
dpc-4237	86	22	%	%	NOUN
dpc-4237	86	23	and	and	CCONJ
dpc-4237	86	24	5.19	5.19	NUM
dpc-4237	86	25	%	%	NOUN
dpc-4237	86	26	.	.	PUNCT
dpc-4237	87	1	the	the	DET
dpc-4237	87	2	reported	report	VERB
dpc-4237	87	3	range	range	NOUN
dpc-4237	87	4	of	of	ADP
dpc-4237	87	5	the	the	DET
dpc-4237	87	6	inter	inter	ADJ
dpc-4237	87	7	-	-	ADJ
dpc-4237	87	8	assay	assay	ADJ
dpc-4237	87	9	cv	cv	PROPN
dpc-4237	87	10	reflects	reflect	VERB
dpc-4237	87	11	the	the	DET
dpc-4237	87	12	consistency	consistency	NOUN
dpc-4237	87	13	of	of	ADP
dpc-4237	87	14	the	the	DET
dpc-4237	87	15	assay	assay	NOUN
dpc-4237	87	16	across	across	ADP
dpc-4237	87	17	different	different	ADJ
dpc-4237	87	18	test	test	NOUN
dpc-4237	87	19	runs	run	NOUN
dpc-4237	87	20	and	and	CCONJ
dpc-4237	87	21	conditions	condition	NOUN
dpc-4237	87	22	.	.	PUNCT
dpc-4237	88	1	these	these	DET
dpc-4237	88	2	coefficients	coefficient	NOUN
dpc-4237	88	3	of	of	ADP
dpc-4237	88	4	variation	variation	NOUN
dpc-4237	88	5	are	be	AUX
dpc-4237	88	6	crucial	crucial	ADJ
dpc-4237	88	7	to	to	ADP
dpc-4237	88	8	evaluating	evaluate	VERB
dpc-4237	88	9	the	the	DET
dpc-4237	88	10	reliability	reliability	NOUN
dpc-4237	88	11	and	and	CCONJ
dpc-4237	88	12	reproducibility	reproducibility	NOUN
dpc-4237	88	13	of	of	ADP
dpc-4237	88	14	the	the	DET
dpc-4237	88	15	assay	assay	PROPN
dpc-4237	88	16	’s	’s	PART
dpc-4237	88	17	results	result	NOUN
dpc-4237	88	18	,	,	PUNCT
dpc-4237	88	19	indicating	indicate	VERB
dpc-4237	88	20	that	that	SCONJ
dpc-4237	88	21	the	the	DET
dpc-4237	88	22	assay	assay	NOUN
dpc-4237	88	23	demonstrates	demonstrate	VERB
dpc-4237	88	24	both	both	DET
dpc-4237	88	25	precision	precision	NOUN
dpc-4237	88	26	and	and	CCONJ
dpc-4237	88	27	consistency	consistency	NOUN
dpc-4237	88	28	in	in	ADP
dpc-4237	88	29	measuring	measure	VERB
dpc-4237	88	30	chitin	chitin	NOUN
dpc-4237	88	31	levels	level	NOUN
dpc-4237	88	32	across	across	ADP
dpc-4237	88	33	multiple	multiple	ADJ
dpc-4237	88	34	tests	test	NOUN
dpc-4237	88	35	and	and	CCONJ
dpc-4237	88	36	conditions	condition	NOUN
dpc-4237	88	37	.	.	PUNCT
dpc-4237	89	1	statistical	statistical	ADJ
dpc-4237	89	2	analysis	analysis	NOUN
dpc-4237	89	3	the	the	DET
dpc-4237	89	4	statistical	statistical	ADJ
dpc-4237	89	5	analyses	analysis	NOUN
dpc-4237	89	6	in	in	ADP
dpc-4237	89	7	this	this	DET
dpc-4237	89	8	study	study	NOUN
dpc-4237	89	9	were	be	AUX
dpc-4237	89	10	conducted	conduct	VERB
dpc-4237	89	11	using	use	VERB
dpc-4237	89	12	the	the	DET
dpc-4237	89	13	statistical	statistical	ADJ
dpc-4237	89	14	package	package	NOUN
dpc-4237	89	15	for	for	ADP
dpc-4237	89	16	social	social	ADJ
dpc-4237	89	17	sciences	science	NOUN
dpc-4237	89	18	(	(	PUNCT
dpc-4237	89	19	spss	spss	PROPN
dpc-4237	89	20	)	)	PUNCT
dpc-4237	89	21	version	version	NOUN
dpc-4237	89	22	15.0	15.0	NUM
dpc-4237	89	23	,	,	PUNCT
dpc-4237	89	24	based	base	VERB
dpc-4237	89	25	in	in	ADP
dpc-4237	89	26	chicago	chicago	PROPN
dpc-4237	89	27	,	,	PUNCT
dpc-4237	89	28	illinois	illinois	PROPN
dpc-4237	89	29	.	.	PUNCT
dpc-4237	90	1	frequencies	frequency	NOUN
dpc-4237	90	2	and	and	CCONJ
dpc-4237	90	3	percentages	percentage	NOUN
dpc-4237	90	4	are	be	AUX
dpc-4237	90	5	used	use	VERB
dpc-4237	90	6	to	to	PART
dpc-4237	90	7	represent	represent	VERB
dpc-4237	90	8	descriptive	descriptive	ADJ
dpc-4237	90	9	categorical	categorical	ADJ
dpc-4237	90	10	data	datum	NOUN
dpc-4237	90	11	,	,	PUNCT
dpc-4237	90	12	while	while	SCONJ
dpc-4237	90	13	continuous	continuous	ADJ
dpc-4237	90	14	data	datum	NOUN
dpc-4237	90	15	are	be	AUX
dpc-4237	90	16	expressed	express	VERB
dpc-4237	90	17	as	as	ADP
dpc-4237	90	18	mean	mean	NOUN
dpc-4237	90	19	±	±	NUM
dpc-4237	90	20	standard	standard	ADJ
dpc-4237	90	21	deviation	deviation	NOUN
dpc-4237	90	22	.	.	PUNCT
dpc-4237	91	1	for	for	ADP
dpc-4237	91	2	normally	normally	ADV
dpc-4237	91	3	distributed	distribute	VERB
dpc-4237	91	4	data	datum	NOUN
dpc-4237	91	5	,	,	PUNCT
dpc-4237	91	6	parametric	parametric	ADJ
dpc-4237	91	7	methods	method	NOUN
dpc-4237	91	8	were	be	AUX
dpc-4237	91	9	employed	employ	VERB
dpc-4237	91	10	.	.	PUNCT
dpc-4237	92	1	the	the	DET
dpc-4237	92	2	independent	independent	ADJ
dpc-4237	92	3	samples	sample	NOUN
dpc-4237	92	4	t	t	NOUN
dpc-4237	92	5	-	-	PUNCT
dpc-4237	92	6	test	test	NOUN
dpc-4237	92	7	(	(	PUNCT
dpc-4237	92	8	t	t	NOUN
dpc-4237	92	9	-	-	PUNCT
dpc-4237	92	10	table	table	NOUN
dpc-4237	92	11	value	value	NOUN
dpc-4237	92	12	)	)	PUNCT
dpc-4237	92	13	was	be	AUX
dpc-4237	92	14	used	use	VERB
dpc-4237	92	15	to	to	PART
dpc-4237	92	16	compare	compare	VERB
dpc-4237	92	17	the	the	DET
dpc-4237	92	18	measurement	measurement	NOUN
dpc-4237	92	19	values	value	NOUN
dpc-4237	92	20	of	of	ADP
dpc-4237	92	21	two	two	NUM
dpc-4237	92	22	independent	independent	ADJ
dpc-4237	92	23	groups	group	NOUN
dpc-4237	92	24	under	under	ADP
dpc-4237	92	25	parametric	parametric	ADJ
dpc-4237	92	26	techniques	technique	NOUN
dpc-4237	92	27	.	.	PUNCT
dpc-4237	93	1	the	the	DET
dpc-4237	93	2	normality	normality	NOUN
dpc-4237	93	3	of	of	ADP
dpc-4237	93	4	the	the	DET
dpc-4237	93	5	continuous	continuous	ADJ
dpc-4237	93	6	data	data	NOUN
dpc-4237	93	7	distribution	distribution	NOUN
dpc-4237	93	8	was	be	AUX
dpc-4237	93	9	assessed	assess	VERB
dpc-4237	93	10	using	use	VERB
dpc-4237	93	11	the	the	DET
dpc-4237	93	12	kolmogorov	kolmogorov	ADJ
dpc-4237	93	13	-	-	PUNCT
dpc-4237	93	14	smirnov	smirnov	ADJ
dpc-4237	93	15	test	test	NOUN
dpc-4237	93	16	.	.	PUNCT
dpc-4237	94	1	nonparametric	nonparametric	NOUN
dpc-4237	94	2	methods	method	NOUN
dpc-4237	94	3	were	be	AUX
dpc-4237	94	4	applied	apply	VERB
dpc-4237	94	5	for	for	ADP
dpc-4237	94	6	data	datum	NOUN
dpc-4237	94	7	that	that	PRON
dpc-4237	94	8	did	do	AUX
dpc-4237	94	9	not	not	PART
dpc-4237	94	10	fit	fit	VERB
dpc-4237	94	11	a	a	DET
dpc-4237	94	12	normal	normal	ADJ
dpc-4237	94	13	distribution	distribution	NOUN
dpc-4237	94	14	,	,	PUNCT
dpc-4237	94	15	using	use	VERB
dpc-4237	94	16	the	the	DET
dpc-4237	94	17	mann	mann	PROPN
dpc-4237	94	18	-	-	PUNCT
dpc-4237	94	19	whitney	whitney	PROPN
dpc-4237	94	20	u	u	PROPN
dpc-4237	94	21	test	test	NOUN
dpc-4237	94	22	(	(	PUNCT
dpc-4237	94	23	z	z	NOUN
dpc-4237	94	24	-	-	PUNCT
dpc-4237	94	25	table	table	NOUN
dpc-4237	94	26	value	value	NOUN
dpc-4237	94	27	)	)	PUNCT
dpc-4237	94	28	to	to	PART
dpc-4237	94	29	compare	compare	VERB
dpc-4237	94	30	the	the	DET
dpc-4237	94	31	measured	measured	ADJ
dpc-4237	94	32	values	value	NOUN
dpc-4237	94	33	between	between	ADP
dpc-4237	94	34	two	two	NUM
dpc-4237	94	35	independent	independent	ADJ
dpc-4237	94	36	groups	group	NOUN
dpc-4237	94	37	.	.	PUNCT
dpc-4237	95	1	pearson	pearson	PROPN
dpc-4237	95	2	-	-	PUNCT
dpc-4237	95	3	χ2	χ2	PROPN
dpc-4237	95	4	test	test	NOUN
dpc-4237	95	5	statistics	statistic	NOUN
dpc-4237	95	6	were	be	AUX
dpc-4237	95	7	used	use	VERB
dpc-4237	95	8	to	to	PART
dpc-4237	95	9	examine	examine	VERB
dpc-4237	95	10	the	the	DET
dpc-4237	95	11	relationship	relationship	NOUN
dpc-4237	95	12	between	between	ADP
dpc-4237	95	13	two	two	NUM
dpc-4237	95	14	qualitative	qualitative	ADJ
dpc-4237	95	15	variables	variable	NOUN
dpc-4237	95	16	.	.	PUNCT
dpc-4237	96	1	binary	binary	ADJ
dpc-4237	96	2	logistic	logistic	ADJ
dpc-4237	96	3	regression	regression	NOUN
dpc-4237	96	4	(	(	PUNCT
dpc-4237	96	5	lr	lr	NOUN
dpc-4237	96	6	):	):	PUNCT
dpc-4237	96	7	the	the	DET
dpc-4237	96	8	backward	backward	ADJ
dpc-4237	96	9	lr	lr	NOUN
dpc-4237	96	10	model	model	NOUN
dpc-4237	96	11	was	be	AUX
dpc-4237	96	12	used	use	VERB
dpc-4237	96	13	to	to	PART
dpc-4237	96	14	determine	determine	VERB
dpc-4237	96	15	the	the	DET
dpc-4237	96	16	factors	factor	NOUN
dpc-4237	96	17	affecting	affect	VERB
dpc-4237	96	18	disease	disease	NOUN
dpc-4237	96	19	risk	risk	NOUN
dpc-4237	96	20	status	status	NOUN
dpc-4237	96	21	.	.	PUNCT
dpc-4237	97	1	p	p	X
dpc-4237	97	2	-	-	PUNCT
dpc-4237	97	3	values	value	NOUN
dpc-4237	97	4	below	below	ADP
dpc-4237	97	5	0.05	0.05	NUM
dpc-4237	97	6	were	be	AUX
dpc-4237	97	7	considered	consider	VERB
dpc-4237	97	8	statistically	statistically	ADV
dpc-4237	97	9	significant	significant	ADJ
dpc-4237	97	10	.	.	PUNCT
dpc-4237	98	1	results	result	VERB
dpc-4237	98	2	characteristics	characteristic	NOUN
dpc-4237	98	3	of	of	ADP
dpc-4237	98	4	participants	participant	NOUN
dpc-4237	98	5	in	in	ADP
dpc-4237	98	6	this	this	DET
dpc-4237	98	7	study	study	NOUN
dpc-4237	98	8	,	,	PUNCT
dpc-4237	98	9	we	we	PRON
dpc-4237	98	10	enrolled	enrol	VERB
dpc-4237	98	11	63	63	NUM
dpc-4237	98	12	patients	patient	NOUN
dpc-4237	98	13	diagnosed	diagnose	VERB
dpc-4237	98	14	with	with	ADP
dpc-4237	98	15	csu	csu	PROPN
dpc-4237	98	16	and	and	CCONJ
dpc-4237	98	17	59	59	NUM
dpc-4237	98	18	healthy	healthy	ADJ
dpc-4237	98	19	controls	control	NOUN
dpc-4237	98	20	,	,	PUNCT
dpc-4237	98	21	matched	match	VERB
dpc-4237	98	22	for	for	ADP
dpc-4237	98	23	age	age	NOUN
dpc-4237	98	24	and	and	CCONJ
dpc-4237	98	25	sex	sex	NOUN
dpc-4237	98	26	.	.	PUNCT
dpc-4237	99	1	all	all	DET
dpc-4237	99	2	participants	participant	NOUN
dpc-4237	99	3	were	be	AUX
dpc-4237	99	4	of	of	ADP
dpc-4237	99	5	turkish	turkish	ADJ
dpc-4237	99	6	descent	descent	NOUN
dpc-4237	99	7	and	and	CCONJ
dpc-4237	99	8	from	from	ADP
dpc-4237	99	9	the	the	DET
dpc-4237	99	10	same	same	ADJ
dpc-4237	99	11	geographic	geographic	ADJ
dpc-4237	99	12	region	region	NOUN
dpc-4237	99	13	.	.	PUNCT
dpc-4237	100	1	the	the	DET
dpc-4237	100	2	median	median	ADJ
dpc-4237	100	3	age	age	NOUN
dpc-4237	100	4	of	of	ADP
dpc-4237	100	5	the	the	DET
dpc-4237	100	6	patients	patient	NOUN
dpc-4237	100	7	was	be	AUX
dpc-4237	100	8	32	32	NUM
dpc-4237	100	9	years	year	NOUN
dpc-4237	100	10	,	,	PUNCT
dpc-4237	100	11	with	with	ADP
dpc-4237	100	12	an	an	DET
dpc-4237	100	13	age	age	NOUN
dpc-4237	100	14	range	range	NOUN
dpc-4237	100	15	of	of	ADP
dpc-4237	100	16	18	18	NUM
dpc-4237	100	17	to	to	PART
dpc-4237	100	18	62	62	NUM
dpc-4237	100	19	years	year	NOUN
dpc-4237	100	20	.	.	PUNCT
dpc-4237	101	1	females	female	NOUN
dpc-4237	101	2	constituted	constitute	VERB
dpc-4237	101	3	52.4	52.4	NUM
dpc-4237	101	4	%	%	NOUN
dpc-4237	101	5	of	of	ADP
dpc-4237	101	6	the	the	DET
dpc-4237	101	7	patient	patient	NOUN
dpc-4237	101	8	group	group	NOUN
dpc-4237	101	9	.	.	PUNCT
dpc-4237	102	1	the	the	DET
dpc-4237	102	2	median	median	ADJ
dpc-4237	102	3	body	body	NOUN
dpc-4237	102	4	mass	mass	NOUN
dpc-4237	102	5	index	index	NOUN
dpc-4237	102	6	(	(	PUNCT
dpc-4237	102	7	bmi	bmi	PROPN
dpc-4237	102	8	)	)	PUNCT
dpc-4237	102	9	was	be	AUX
dpc-4237	102	10	recorded	record	VERB
dpc-4237	102	11	at	at	ADP
dpc-4237	102	12	25	25	NUM
dpc-4237	102	13	kg	kg	NOUN
dpc-4237	102	14	/	/	SYM
dpc-4237	102	15	m²	m²	PROPN
dpc-4237	102	16	,	,	PUNCT
dpc-4237	102	17	ranging	range	VERB
dpc-4237	102	18	from	from	ADP
dpc-4237	102	19	17.9	17.9	NUM
dpc-4237	102	20	to	to	PART
dpc-4237	102	21	29.8	29.8	NUM
dpc-4237	102	22	kg	kg	NOUN
dpc-4237	102	23	/	/	SYM
dpc-4237	102	24	m²	m²	PROPN
dpc-4237	102	25	.	.	PUNCT
dpc-4237	103	1	comparative	comparative	ADJ
dpc-4237	103	2	analysis	analysis	NOUN
dpc-4237	103	3	revealed	reveal	VERB
dpc-4237	103	4	no	no	DET
dpc-4237	103	5	significant	significant	ADJ
dpc-4237	103	6	differences	difference	NOUN
dpc-4237	103	7	in	in	ADP
dpc-4237	103	8	age	age	NOUN
dpc-4237	103	9	,	,	PUNCT
dpc-4237	103	10	sex	sex	NOUN
dpc-4237	103	11	,	,	PUNCT
dpc-4237	103	12	or	or	CCONJ
dpc-4237	103	13	bmi	bmi	NOUN
dpc-4237	103	14	between	between	ADP
dpc-4237	103	15	the	the	DET
dpc-4237	103	16	csu	csu	PROPN
dpc-4237	103	17	patients	patient	NOUN
dpc-4237	103	18	and	and	CCONJ
dpc-4237	103	19	the	the	DET
dpc-4237	103	20	control	control	NOUN
dpc-4237	103	21	group	group	NOUN
dpc-4237	103	22	.	.	PUNCT
dpc-4237	104	1	the	the	DET
dpc-4237	104	2	demographic	demographic	ADJ
dpc-4237	104	3	and	and	CCONJ
dpc-4237	104	4	clinical	clinical	ADJ
dpc-4237	104	5	characteristics	characteristic	NOUN
dpc-4237	104	6	of	of	ADP
dpc-4237	104	7	the	the	DET
dpc-4237	104	8	study	study	NOUN
dpc-4237	104	9	groups	group	NOUN
dpc-4237	104	10	are	be	AUX
dpc-4237	104	11	detailed	detail	VERB
dpc-4237	104	12	in	in	ADP
dpc-4237	104	13	table	table	NOUN
dpc-4237	104	14	1	1	NUM
dpc-4237	104	15	.	.	PUNCT
dpc-4237	105	1	a	a	DET
dpc-4237	105	2	key	key	ADJ
dpc-4237	105	3	focus	focus	NOUN
dpc-4237	105	4	of	of	ADP
dpc-4237	105	5	our	our	PRON
dpc-4237	105	6	study	study	NOUN
dpc-4237	105	7	was	be	AUX
dpc-4237	105	8	on	on	ADP
dpc-4237	105	9	serum	serum	PROPN
dpc-4237	105	10	zonulin	zonulin	PROPN
dpc-4237	105	11	levels	level	NOUN
dpc-4237	105	12	,	,	PUNCT
dpc-4237	105	13	a	a	DET
dpc-4237	105	14	marker	marker	NOUN
dpc-4237	105	15	of	of	ADP
dpc-4237	105	16	intestinal	intestinal	ADJ
dpc-4237	105	17	permeability	permeability	NOUN
dpc-4237	105	18	.	.	PUNCT
dpc-4237	106	1	the	the	DET
dpc-4237	106	2	median	median	ADJ
dpc-4237	106	3	zonulin	zonulin	PROPN
dpc-4237	106	4	level	level	NOUN
dpc-4237	106	5	in	in	ADP
dpc-4237	106	6	the	the	DET
dpc-4237	106	7	csu	csu	PROPN
dpc-4237	106	8	patient	patient	PROPN
dpc-4237	106	9	group	group	NOUN
dpc-4237	106	10	was	be	AUX
dpc-4237	106	11	49.3	49.3	NUM
dpc-4237	106	12	ng	ng	PROPN
dpc-4237	106	13	/	/	SYM
dpc-4237	106	14	ml	ml	PROPN
dpc-4237	106	15	(	(	PUNCT
dpc-4237	106	16	range	range	NOUN
dpc-4237	106	17	:	:	PUNCT
dpc-4237	106	18	2.2	2.2	NUM
dpc-4237	106	19	-	-	SYM
dpc-4237	106	20	58.3	58.3	NUM
dpc-4237	106	21	ng	ng	PROPN
dpc-4237	106	22	/	/	SYM
dpc-4237	106	23	ml	ml	PROPN
dpc-4237	106	24	)	)	PUNCT
dpc-4237	106	25	,	,	PUNCT
dpc-4237	106	26	which	which	PRON
dpc-4237	106	27	was	be	AUX
dpc-4237	106	28	notably	notably	ADV
dpc-4237	106	29	higher	high	ADJ
dpc-4237	106	30	than	than	ADP
dpc-4237	106	31	in	in	ADP
dpc-4237	106	32	the	the	DET
dpc-4237	106	33	control	control	NOUN
dpc-4237	106	34	group	group	NOUN
dpc-4237	106	35	,	,	PUNCT
dpc-4237	106	36	which	which	PRON
dpc-4237	106	37	had	have	VERB
dpc-4237	106	38	a	a	DET
dpc-4237	106	39	median	median	NOUN
dpc-4237	106	40	of	of	ADP
dpc-4237	106	41	41.9	41.9	NUM
dpc-4237	106	42	ng	ng	PROPN
dpc-4237	106	43	/	/	SYM
dpc-4237	106	44	ml	ml	PROPN
dpc-4237	106	45	(	(	PUNCT
dpc-4237	106	46	range	range	NOUN
dpc-4237	106	47	:	:	PUNCT
dpc-4237	106	48	2.2	2.2	NUM
dpc-4237	106	49	-	-	SYM
dpc-4237	106	50	56.3	56.3	NUM
dpc-4237	106	51	ng	ng	PROPN
dpc-4237	106	52	/	/	SYM
dpc-4237	106	53	ml	ml	PROPN
dpc-4237	106	54	)	)	PUNCT
dpc-4237	106	55	.	.	PUNCT
dpc-4237	107	1	this	this	DET
dpc-4237	107	2	difference	difference	NOUN
dpc-4237	107	3	was	be	AUX
dpc-4237	107	4	statistically	statistically	ADV
dpc-4237	107	5	significant	significant	ADJ
dpc-4237	107	6	(	(	PUNCT
dpc-4237	107	7	p=0.000	p=0.000	NOUN
dpc-4237	107	8	)	)	PUNCT
dpc-4237	107	9	,	,	PUNCT
dpc-4237	107	10	suggesting	suggest	VERB
dpc-4237	107	11	a	a	DET
dpc-4237	107	12	potential	potential	ADJ
dpc-4237	107	13	link	link	NOUN
dpc-4237	107	14	between	between	ADP
dpc-4237	107	15	increased	increase	VERB
dpc-4237	107	16	intestinal	intestinal	ADJ
dpc-4237	107	17	permeability	permeability	NOUN
dpc-4237	107	18	and	and	CCONJ
dpc-4237	107	19	csu	csu	PROPN
dpc-4237	107	20	.	.	PUNCT
dpc-4237	108	1	our	our	PRON
dpc-4237	108	2	study	study	NOUN
dpc-4237	108	3	also	also	ADV
dpc-4237	108	4	categorized	categorize	VERB
dpc-4237	108	5	csu	csu	PROPN
dpc-4237	108	6	patients	patient	NOUN
dpc-4237	108	7	4	4	NUM
dpc-4237	108	8	original	original	ADJ
dpc-4237	108	9	article	article	NOUN
dpc-4237	108	10	|	|	ADV
dpc-4237	108	11	dermatol	dermatol	ADJ
dpc-4237	108	12	pract	pract	NOUN
dpc-4237	108	13	concept	concept	NOUN
dpc-4237	108	14	.	.	PUNCT
dpc-4237	109	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	109	2	autoimmune	autoimmune	ADJ
dpc-4237	109	3	immunity	immunity	NOUN
dpc-4237	109	4	is	be	AUX
dpc-4237	109	5	a	a	DET
dpc-4237	109	6	significant	significant	ADJ
dpc-4237	109	7	predisposing	predispose	VERB
dpc-4237	109	8	factor	factor	NOUN
dpc-4237	109	9	given	give	VERB
dpc-4237	109	10	the	the	DET
dpc-4237	109	11	co	co	NOUN
dpc-4237	109	12	-	-	NOUN
dpc-4237	109	13	occurrence	occurrence	NOUN
dpc-4237	109	14	of	of	ADP
dpc-4237	109	15	autoimmune	autoimmune	ADJ
dpc-4237	109	16	illnesses	illness	NOUN
dpc-4237	109	17	,	,	PUNCT
dpc-4237	109	18	the	the	DET
dpc-4237	109	19	presence	presence	NOUN
dpc-4237	109	20	of	of	ADP
dpc-4237	109	21	many	many	ADJ
dpc-4237	109	22	autoantibodies	autoantibody	NOUN
dpc-4237	109	23	,	,	PUNCT
dpc-4237	109	24	the	the	DET
dpc-4237	109	25	higher	high	ADJ
dpc-4237	109	26	frequency	frequency	NOUN
dpc-4237	109	27	in	in	ADP
dpc-4237	109	28	females	female	NOUN
dpc-4237	109	29	,	,	PUNCT
dpc-4237	109	30	and	and	CCONJ
dpc-4237	109	31	the	the	DET
dpc-4237	109	32	response	response	NOUN
dpc-4237	109	33	to	to	ADP
dpc-4237	109	34	the	the	DET
dpc-4237	109	35	ige	ige	PROPN
dpc-4237	109	36	monoclonal	monoclonal	NOUN
dpc-4237	109	37	antibody	antibody	NOUN
dpc-4237	109	38	omalizumab	omalizumab	NOUN
dpc-4237	109	39	.	.	PUNCT
dpc-4237	110	1	it	it	PRON
dpc-4237	110	2	is	be	AUX
dpc-4237	110	3	believed	believe	VERB
dpc-4237	110	4	that	that	SCONJ
dpc-4237	110	5	the	the	DET
dpc-4237	110	6	intestine	intestine	NOUN
dpc-4237	110	7	plays	play	VERB
dpc-4237	110	8	a	a	DET
dpc-4237	110	9	role	role	NOUN
dpc-4237	110	10	in	in	ADP
dpc-4237	110	11	the	the	DET
dpc-4237	110	12	development	development	NOUN
dpc-4237	110	13	of	of	ADP
dpc-4237	110	14	autoimmune	autoimmune	ADJ
dpc-4237	110	15	illnesses	illness	NOUN
dpc-4237	110	16	and	and	CCONJ
dpc-4237	110	17	greatly	greatly	ADV
dpc-4237	110	18	influences	influence	VERB
dpc-4237	110	19	the	the	DET
dpc-4237	110	20	onset	onset	NOUN
dpc-4237	110	21	of	of	ADP
dpc-4237	110	22	these	these	DET
dpc-4237	110	23	processes	process	NOUN
dpc-4237	110	24	.	.	PUNCT
dpc-4237	111	1	it	it	PRON
dpc-4237	111	2	has	have	AUX
dpc-4237	111	3	been	be	AUX
dpc-4237	111	4	shown	show	VERB
dpc-4237	111	5	that	that	SCONJ
dpc-4237	111	6	disruption	disruption	NOUN
dpc-4237	111	7	of	of	ADP
dpc-4237	111	8	the	the	DET
dpc-4237	111	9	integrity	integrity	NOUN
dpc-4237	111	10	of	of	ADP
dpc-4237	111	11	the	the	DET
dpc-4237	111	12	connections	connection	NOUN
dpc-4237	111	13	between	between	ADP
dpc-4237	111	14	enterocytes	enterocyte	NOUN
dpc-4237	111	15	in	in	ADP
dpc-4237	111	16	the	the	DET
dpc-4237	111	17	small	small	ADJ
dpc-4237	111	18	intestine	intestine	NOUN
dpc-4237	111	19	causes	cause	VERB
dpc-4237	111	20	an	an	DET
dpc-4237	111	21	increase	increase	NOUN
dpc-4237	111	22	in	in	ADP
dpc-4237	111	23	intestinal	intestinal	ADJ
dpc-4237	111	24	permeability	permeability	NOUN
dpc-4237	111	25	,	,	PUNCT
dpc-4237	111	26	and	and	CCONJ
dpc-4237	111	27	zonulin	zonulin	NOUN
dpc-4237	111	28	is	be	AUX
dpc-4237	111	29	a	a	DET
dpc-4237	111	30	protein	protein	NOUN
dpc-4237	111	31	that	that	PRON
dpc-4237	111	32	physiologically	physiologically	ADV
dpc-4237	111	33	modulates	modulate	VERB
dpc-4237	111	34	tight	tight	ADJ
dpc-4237	111	35	junctions	junction	NOUN
dpc-4237	111	36	(	(	PUNCT
dpc-4237	111	37	tj	tj	NOUN
dpc-4237	111	38	)	)	PUNCT
dpc-4237	111	39	between	between	ADP
dpc-4237	111	40	enterocytes	enterocyte	NOUN
dpc-4237	111	41	[	[	X
dpc-4237	111	42	8,10,12	8,10,12	NUM
dpc-4237	111	43	]	]	PUNCT
dpc-4237	111	44	.	.	PUNCT
dpc-4237	112	1	gliadin	gliadin	NOUN
dpc-4237	112	2	and	and	CCONJ
dpc-4237	112	3	bacteria	bacteria	NOUN
dpc-4237	112	4	are	be	AUX
dpc-4237	112	5	primary	primary	ADJ
dpc-4237	112	6	factors	factor	NOUN
dpc-4237	112	7	that	that	PRON
dpc-4237	112	8	cause	cause	VERB
dpc-4237	112	9	zonulin	zonulin	PROPN
dpc-4237	112	10	to	to	PART
dpc-4237	112	11	be	be	AUX
dpc-4237	112	12	released	release	VERB
dpc-4237	112	13	[	[	PUNCT
dpc-4237	112	14	8	8	NUM
dpc-4237	112	15	]	]	PUNCT
dpc-4237	112	16	.	.	PUNCT
dpc-4237	113	1	enterotoxin	enterotoxin	VERB
dpc-4237	113	2	generation	generation	NOUN
dpc-4237	113	3	from	from	ADP
dpc-4237	113	4	numerous	numerous	ADJ
dpc-4237	113	5	enteric	enteric	ADJ
dpc-4237	113	6	infections	infection	NOUN
dpc-4237	113	7	that	that	PRON
dpc-4237	113	8	impact	impact	VERB
dpc-4237	113	9	the	the	DET
dpc-4237	113	10	tight	tight	ADJ
dpc-4237	113	11	junction	junction	NOUN
dpc-4237	113	12	in	in	ADP
dpc-4237	113	13	the	the	DET
dpc-4237	113	14	host	host	NOUN
dpc-4237	113	15	’s	’s	PART
dpc-4237	113	16	gut	gut	NOUN
dpc-4237	113	17	also	also	ADV
dpc-4237	113	18	contributes	contribute	VERB
dpc-4237	113	19	to	to	ADP
dpc-4237	113	20	zonulin	zonulin	PROPN
dpc-4237	113	21	production	production	NOUN
dpc-4237	113	22	.	.	PUNCT
dpc-4237	114	1	in	in	ADP
dpc-4237	114	2	both	both	DET
dpc-4237	114	3	culture	culture	NOUN
dpc-4237	114	4	models	model	NOUN
dpc-4237	114	5	and	and	CCONJ
dpc-4237	114	6	ex	ex	PRON
dpc-4237	114	7	vivo	vivo	ADJ
dpc-4237	114	8	experiments	experiment	NOUN
dpc-4237	114	9	,	,	PUNCT
dpc-4237	114	10	gliadin	gliadin	VERB
dpc-4237	114	11	administered	administer	VERB
dpc-4237	114	12	to	to	ADP
dpc-4237	114	13	the	the	DET
dpc-4237	114	14	apical	apical	ADJ
dpc-4237	114	15	surface	surface	NOUN
dpc-4237	114	16	of	of	ADP
dpc-4237	114	17	cells	cell	NOUN
dpc-4237	114	18	promotes	promote	VERB
dpc-4237	114	19	zonulin	zonulin	PROPN
dpc-4237	114	20	release	release	VERB
dpc-4237	114	21	through	through	ADP
dpc-4237	114	22	cxcr3	cxcr3	NOUN
dpc-4237	114	23	receptors	receptor	NOUN
dpc-4237	114	24	[	[	X
dpc-4237	114	25	8	8	NUM
dpc-4237	114	26	]	]	PUNCT
dpc-4237	114	27	.	.	PUNCT
dpc-4237	115	1	recent	recent	ADJ
dpc-4237	115	2	years	year	NOUN
dpc-4237	115	3	have	have	AUX
dpc-4237	115	4	seen	see	VERB
dpc-4237	115	5	an	an	DET
dpc-4237	115	6	association	association	NOUN
dpc-4237	115	7	between	between	ADP
dpc-4237	115	8	zonulin	zonulin	PROPN
dpc-4237	115	9	increase	increase	NOUN
dpc-4237	115	10	and	and	CCONJ
dpc-4237	115	11	autoimmune	autoimmune	ADJ
dpc-4237	115	12	diseases	disease	NOUN
dpc-4237	115	13	such	such	ADJ
dpc-4237	115	14	as	as	ADP
dpc-4237	115	15	celiac	celiac	ADJ
dpc-4237	115	16	disease	disease	NOUN
dpc-4237	115	17	,	,	PUNCT
dpc-4237	115	18	type	type	NOUN
dpc-4237	115	19	1	1	NUM
dpc-4237	115	20	diabetes	diabetes	NOUN
dpc-4237	115	21	mellitus	mellitus	NOUN
dpc-4237	115	22	,	,	PUNCT
dpc-4237	115	23	inflammatory	inflammatory	ADJ
dpc-4237	115	24	bowel	bowel	NOUN
dpc-4237	115	25	diseases	disease	NOUN
dpc-4237	115	26	,	,	PUNCT
dpc-4237	115	27	and	and	CCONJ
dpc-4237	115	28	multiple	multiple	ADJ
dpc-4237	115	29	sclerosis	sclerosis	NOUN
dpc-4237	115	30	[	[	X
dpc-4237	115	31	8	8	NUM
dpc-4237	115	32	]	]	PUNCT
dpc-4237	115	33	.	.	PUNCT
dpc-4237	116	1	it	it	PRON
dpc-4237	116	2	is	be	AUX
dpc-4237	116	3	thought	think	VERB
dpc-4237	116	4	that	that	SCONJ
dpc-4237	116	5	the	the	DET
dpc-4237	116	6	increase	increase	NOUN
dpc-4237	116	7	in	in	ADP
dpc-4237	116	8	intestinal	intestinal	ADJ
dpc-4237	116	9	permeability	permeability	NOUN
dpc-4237	116	10	may	may	AUX
dpc-4237	116	11	occur	occur	VERB
dpc-4237	116	12	alongside	alongside	ADP
dpc-4237	116	13	or	or	CCONJ
dpc-4237	116	14	before	before	ADP
dpc-4237	116	15	the	the	DET
dpc-4237	116	16	clinical	clinical	ADJ
dpc-4237	116	17	as	as	ADP
dpc-4237	116	18	mild	mild	ADJ
dpc-4237	116	19	,	,	PUNCT
dpc-4237	116	20	moderate	moderate	ADJ
dpc-4237	116	21	,	,	PUNCT
dpc-4237	116	22	or	or	CCONJ
dpc-4237	116	23	severe	severe	ADJ
dpc-4237	116	24	based	base	VERB
dpc-4237	116	25	on	on	ADP
dpc-4237	116	26	the	the	DET
dpc-4237	116	27	uas	uas	PROPN
dpc-4237	116	28	.	.	PUNCT
dpc-4237	117	1	however	however	ADV
dpc-4237	117	2	,	,	PUNCT
dpc-4237	117	3	no	no	DET
dpc-4237	117	4	statistically	statistically	ADV
dpc-4237	117	5	significant	significant	ADJ
dpc-4237	117	6	correlation	correlation	NOUN
dpc-4237	117	7	was	be	AUX
dpc-4237	117	8	found	find	VERB
dpc-4237	117	9	between	between	ADP
dpc-4237	117	10	serum	serum	PROPN
dpc-4237	117	11	zonulin	zonulin	PROPN
dpc-4237	117	12	levels	level	NOUN
dpc-4237	117	13	and	and	CCONJ
dpc-4237	117	14	the	the	DET
dpc-4237	117	15	severity	severity	NOUN
dpc-4237	117	16	of	of	ADP
dpc-4237	117	17	csu	csu	NOUN
dpc-4237	117	18	in	in	ADP
dpc-4237	117	19	this	this	DET
dpc-4237	117	20	stratification	stratification	NOUN
dpc-4237	117	21	.	.	PUNCT
dpc-4237	118	1	gender	gender	NOUN
dpc-4237	118	2	-	-	PUNCT
dpc-4237	118	3	based	base	VERB
dpc-4237	118	4	analysis	analysis	NOUN
dpc-4237	118	5	within	within	ADP
dpc-4237	118	6	the	the	DET
dpc-4237	118	7	csu	csu	PROPN
dpc-4237	118	8	group	group	NOUN
dpc-4237	118	9	revealed	reveal	VERB
dpc-4237	118	10	that	that	SCONJ
dpc-4237	118	11	serum	serum	PROPN
dpc-4237	118	12	zonulin	zonulin	PROPN
dpc-4237	118	13	levels	level	NOUN
dpc-4237	118	14	were	be	AUX
dpc-4237	118	15	significantly	significantly	ADV
dpc-4237	118	16	higher	high	ADJ
dpc-4237	118	17	in	in	ADP
dpc-4237	118	18	female	female	ADJ
dpc-4237	118	19	patients	patient	NOUN
dpc-4237	118	20	compared	compare	VERB
dpc-4237	118	21	to	to	ADP
dpc-4237	118	22	their	their	PRON
dpc-4237	118	23	male	male	ADJ
dpc-4237	118	24	counterparts	counterpart	NOUN
dpc-4237	118	25	.	.	PUNCT
dpc-4237	119	1	additionally	additionally	ADV
dpc-4237	119	2	,	,	PUNCT
dpc-4237	119	3	patients	patient	NOUN
dpc-4237	119	4	with	with	ADP
dpc-4237	119	5	csu	csu	PROPN
dpc-4237	119	6	who	who	PRON
dpc-4237	119	7	also	also	ADV
dpc-4237	119	8	had	have	AUX
dpc-4237	119	9	angioedema	angioedema	ADV
dpc-4237	119	10	exhibited	exhibit	VERB
dpc-4237	119	11	significantly	significantly	ADV
dpc-4237	119	12	higher	high	ADJ
dpc-4237	119	13	zonulin	zonulin	PROPN
dpc-4237	119	14	levels	level	NOUN
dpc-4237	119	15	compared	compare	VERB
dpc-4237	119	16	to	to	ADP
dpc-4237	119	17	those	those	PRON
dpc-4237	119	18	without	without	ADP
dpc-4237	119	19	angioedema	angioedema	NOUN
dpc-4237	119	20	(	(	PUNCT
dpc-4237	119	21	p=0.023	p=0.023	NUM
dpc-4237	119	22	)	)	PUNCT
dpc-4237	119	23	.	.	PUNCT
dpc-4237	120	1	table	table	NOUN
dpc-4237	120	2	2	2	NUM
dpc-4237	120	3	provides	provide	VERB
dpc-4237	120	4	a	a	DET
dpc-4237	120	5	comprehensive	comprehensive	ADJ
dpc-4237	120	6	breakdown	breakdown	NOUN
dpc-4237	120	7	of	of	ADP
dpc-4237	120	8	the	the	DET
dpc-4237	120	9	correlations	correlation	NOUN
dpc-4237	120	10	between	between	ADP
dpc-4237	120	11	zonulin	zonulin	PROPN
dpc-4237	120	12	levels	level	NOUN
dpc-4237	120	13	,	,	PUNCT
dpc-4237	120	14	sex	sex	NOUN
dpc-4237	120	15	,	,	PUNCT
dpc-4237	120	16	the	the	DET
dpc-4237	120	17	severity	severity	NOUN
dpc-4237	120	18	of	of	ADP
dpc-4237	120	19	csu	csu	PROPN
dpc-4237	120	20	,	,	PUNCT
dpc-4237	120	21	and	and	CCONJ
dpc-4237	120	22	the	the	DET
dpc-4237	120	23	presence	presence	NOUN
dpc-4237	120	24	of	of	ADP
dpc-4237	120	25	angioedema	angioedema	ADV
dpc-4237	120	26	,	,	PUNCT
dpc-4237	120	27	offering	offer	VERB
dpc-4237	120	28	further	further	ADJ
dpc-4237	120	29	insights	insight	NOUN
dpc-4237	120	30	into	into	ADP
dpc-4237	120	31	the	the	DET
dpc-4237	120	32	complexities	complexity	NOUN
dpc-4237	120	33	of	of	ADP
dpc-4237	120	34	this	this	DET
dpc-4237	120	35	condition	condition	NOUN
dpc-4237	120	36	.	.	PUNCT
dpc-4237	121	1	discussion	discussion	NOUN
dpc-4237	121	2	in	in	ADP
dpc-4237	121	3	this	this	DET
dpc-4237	121	4	study	study	NOUN
dpc-4237	121	5	,	,	PUNCT
dpc-4237	121	6	we	we	PRON
dpc-4237	121	7	examined	examine	VERB
dpc-4237	121	8	serum	serum	PROPN
dpc-4237	121	9	zonulin	zonulin	PROPN
dpc-4237	121	10	levels	level	NOUN
dpc-4237	121	11	to	to	PART
dpc-4237	121	12	determine	determine	VERB
dpc-4237	121	13	whether	whether	SCONJ
dpc-4237	121	14	intestinal	intestinal	ADJ
dpc-4237	121	15	permeability	permeability	NOUN
dpc-4237	121	16	contributes	contribute	VERB
dpc-4237	121	17	to	to	ADP
dpc-4237	121	18	the	the	DET
dpc-4237	121	19	pathophysiology	pathophysiology	NOUN
dpc-4237	121	20	of	of	ADP
dpc-4237	121	21	csu	csu	PROPN
dpc-4237	121	22	.	.	PUNCT
dpc-4237	122	1	we	we	PRON
dpc-4237	122	2	found	find	VERB
dpc-4237	122	3	that	that	SCONJ
dpc-4237	122	4	csu	csu	PROPN
dpc-4237	122	5	patients	patient	NOUN
dpc-4237	122	6	had	have	VERB
dpc-4237	122	7	significantly	significantly	ADV
dpc-4237	122	8	higher	high	ADJ
dpc-4237	122	9	serum	serum	PROPN
dpc-4237	122	10	zonulin	zonulin	PROPN
dpc-4237	122	11	levels	level	NOUN
dpc-4237	122	12	than	than	ADP
dpc-4237	122	13	the	the	DET
dpc-4237	122	14	control	control	NOUN
dpc-4237	122	15	group	group	NOUN
dpc-4237	122	16	.	.	PUNCT
dpc-4237	123	1	factors	factor	NOUN
dpc-4237	123	2	such	such	ADJ
dpc-4237	123	3	as	as	ADP
dpc-4237	123	4	pseudoallergens	pseudoallergen	NOUN
dpc-4237	123	5	,	,	PUNCT
dpc-4237	123	6	dysbiosis	dysbiosis	NOUN
dpc-4237	123	7	,	,	PUNCT
dpc-4237	123	8	metabolic	metabolic	NOUN
dpc-4237	123	9	syndrome	syndrome	NOUN
dpc-4237	123	10	,	,	PUNCT
dpc-4237	123	11	autoimmune	autoimmune	ADJ
dpc-4237	123	12	reactions	reaction	NOUN
dpc-4237	123	13	,	,	PUNCT
dpc-4237	123	14	stress	stress	NOUN
dpc-4237	123	15	,	,	PUNCT
dpc-4237	123	16	and	and	CCONJ
dpc-4237	123	17	certain	certain	ADJ
dpc-4237	123	18	medications	medication	NOUN
dpc-4237	123	19	are	be	AUX
dpc-4237	123	20	considered	consider	VERB
dpc-4237	123	21	predisposing	predispose	VERB
dpc-4237	123	22	factors	factor	NOUN
dpc-4237	123	23	in	in	ADP
dpc-4237	123	24	the	the	DET
dpc-4237	123	25	etiology	etiology	NOUN
dpc-4237	123	26	of	of	ADP
dpc-4237	123	27	csu	csu	PROPN
dpc-4237	123	28	.	.	PUNCT
dpc-4237	123	29	table	table	NOUN
dpc-4237	124	1	1	1	NUM
dpc-4237	124	2	.	.	PUNCT
dpc-4237	125	1	demographics	demographic	NOUN
dpc-4237	125	2	and	and	CCONJ
dpc-4237	125	3	clinical	clinical	ADJ
dpc-4237	125	4	characteristics	characteristic	NOUN
dpc-4237	125	5	of	of	ADP
dpc-4237	125	6	participants	participant	NOUN
dpc-4237	125	7	.	.	PUNCT
dpc-4237	126	1	characteristic	characteristic	ADJ
dpc-4237	126	2	csu	csu	PROPN
dpc-4237	126	3	patients	patient	NOUN
dpc-4237	126	4	(	(	PUNCT
dpc-4237	126	5	n=63	n=63	ADJ
dpc-4237	126	6	)	)	PUNCT
dpc-4237	126	7	healthy	healthy	ADJ
dpc-4237	126	8	controls	control	NOUN
dpc-4237	126	9	(	(	PUNCT
dpc-4237	126	10	n=59	n=59	X
dpc-4237	126	11	)	)	PUNCT
dpc-4237	126	12	p	p	NOUN
dpc-4237	126	13	-	-	PUNCT
dpc-4237	126	14	value	value	NOUN
dpc-4237	126	15	w	w	NOUN
dpc-4237	126	16	male	male	ADJ
dpc-4237	126	17	/	/	SYM
dpc-4237	126	18	female	female	ADJ
dpc-4237	126	19	(	(	PUNCT
dpc-4237	126	20	n	n	CCONJ
dpc-4237	126	21	)	)	PUNCT
dpc-4237	126	22	30	30	NUM
dpc-4237	126	23	/	/	SYM
dpc-4237	126	24	33	33	NUM
dpc-4237	126	25	29/	29/	NUM
dpc-4237	126	26	30	30	NUM
dpc-4237	126	27	0.865	0.865	NUM
dpc-4237	126	28	age	age	NOUN
dpc-4237	126	29	(	(	PUNCT
dpc-4237	126	30	range	range	NOUN
dpc-4237	126	31	)	)	PUNCT
dpc-4237	126	32	34.95	34.95	NUM
dpc-4237	126	33	±	±	NUM
dpc-4237	126	34	11.68	11.68	NUM
dpc-4237	126	35	(	(	PUNCT
dpc-4237	126	36	18	18	NUM
dpc-4237	126	37	-	-	SYM
dpc-4237	126	38	62	62	NUM
dpc-4237	126	39	)	)	PUNCT
dpc-4237	126	40	34.93	34.93	NUM
dpc-4237	126	41	±	±	NUM
dpc-4237	126	42	9.07	9.07	NUM
dpc-4237	126	43	(	(	PUNCT
dpc-4237	126	44	18	18	NUM
dpc-4237	126	45	-	-	SYM
dpc-4237	126	46	53	53	NUM
dpc-4237	126	47	)	)	PUNCT
dpc-4237	126	48	0.743	0.743	NUM
dpc-4237	126	49	bmi	bmi	NOUN
dpc-4237	126	50	(	(	PUNCT
dpc-4237	126	51	body	body	NOUN
dpc-4237	126	52	mass	mass	PROPN
dpc-4237	126	53	index	index	PROPN
dpc-4237	126	54	)	)	PUNCT
dpc-4237	126	55	24.79	24.79	NUM
dpc-4237	126	56	±	±	NUM
dpc-4237	126	57	3.03	3.03	NUM
dpc-4237	126	58	24.28	24.28	NUM
dpc-4237	126	59	±	±	NUM
dpc-4237	126	60	3.19	3.19	NUM
dpc-4237	126	61	0.360	0.360	NUM
dpc-4237	126	62	cigarette	cigarette	NOUN
dpc-4237	126	63	pack	pack	NOUN
dpc-4237	126	64	year	year	NOUN
dpc-4237	126	65	(	(	PUNCT
dpc-4237	126	66	+	+	NOUN
dpc-4237	126	67	/-	/-	X
dpc-4237	126	68	)	)	PUNCT
dpc-4237	126	69	19/49	19/49	NUM
dpc-4237	126	70	17/41	17/41	NUM
dpc-4237	126	71	0.919	0.919	NUM
dpc-4237	126	72	history	history	NOUN
dpc-4237	126	73	of	of	ADP
dpc-4237	126	74	alcohol	alcohol	NOUN
dpc-4237	126	75	use	use	NOUN
dpc-4237	126	76	(	(	PUNCT
dpc-4237	126	77	+	+	NOUN
dpc-4237	126	78	/-	/-	PUNCT
dpc-4237	126	79	)	)	PUNCT
dpc-4237	127	1	5/58	5/58	NUM
dpc-4237	127	2	3/56	3/56	NUM
dpc-4237	127	3	0.525	0.525	NUM
dpc-4237	127	4	disease	disease	NOUN
dpc-4237	127	5	duration	duration	NOUN
dpc-4237	127	6	(	(	PUNCT
dpc-4237	127	7	month	month	NOUN
dpc-4237	127	8	)	)	PUNCT
dpc-4237	127	9	47.95±	47.95±	NUM
dpc-4237	127	10	89.34	89.34	NUM
dpc-4237	127	11	(	(	PUNCT
dpc-4237	127	12	2	2	NUM
dpc-4237	127	13	-	-	SYM
dpc-4237	127	14	396	396	NUM
dpc-4237	127	15	)	)	PUNCT
dpc-4237	127	16	last	last	ADJ
dpc-4237	127	17	attack	attack	NOUN
dpc-4237	127	18	(	(	PUNCT
dpc-4237	127	19	week	week	NOUN
dpc-4237	127	20	)	)	PUNCT
dpc-4237	127	21	8.91±12.67(0	8.91±12.67(0	NUM
dpc-4237	127	22	-	-	SYM
dpc-4237	127	23	72	72	NUM
dpc-4237	127	24	)	)	PUNCT
dpc-4237	127	25	plaque	plaque	NOUN
dpc-4237	127	26	residence	residence	NOUN
dpc-4237	127	27	duration	duration	NOUN
dpc-4237	127	28	4.46±4.02(0	4.46±4.02(0	NOUN
dpc-4237	127	29	-	-	SYM
dpc-4237	127	30	24	24	NUM
dpc-4237	127	31	)	)	PUNCT
dpc-4237	127	32	serum	serum	NOUN
dpc-4237	127	33	zonulin	zonulin	PROPN
dpc-4237	127	34	level	level	NOUN
dpc-4237	127	35	(	(	PUNCT
dpc-4237	127	36	range	range	NOUN
dpc-4237	127	37	)	)	PUNCT
dpc-4237	127	38	45.99±10.71(2.2	45.99±10.71(2.2	NUM
dpc-4237	127	39	-	-	SYM
dpc-4237	127	40	58.3	58.3	NUM
dpc-4237	127	41	)	)	PUNCT
dpc-4237	127	42	37.63±15.09(2.2	37.63±15.09(2.2	PROPN
dpc-4237	127	43	-	-	NUM
dpc-4237	127	44	56.3	56.3	NUM
dpc-4237	127	45	)	)	PUNCT
dpc-4237	127	46	*	*	SYM
dpc-4237	127	47	0.000	0.000	NUM
dpc-4237	127	48	abbreviation	abbreviation	NOUN
dpc-4237	127	49	:	:	PUNCT
dpc-4237	127	50	csu	csu	VERB
dpc-4237	127	51	:	:	PUNCT
dpc-4237	127	52	chronic	chronic	ADJ
dpc-4237	127	53	spontaneous	spontaneous	ADJ
dpc-4237	127	54	urticaria	urticaria	NOUN
dpc-4237	127	55	.	.	PUNCT
dpc-4237	128	1	table	table	NOUN
dpc-4237	128	2	2	2	NUM
dpc-4237	128	3	.	.	X
dpc-4237	128	4	relationship	relationship	NOUN
dpc-4237	128	5	between	between	ADP
dpc-4237	128	6	zonulin	zonulin	PROPN
dpc-4237	128	7	levels	level	NOUN
dpc-4237	128	8	,	,	PUNCT
dpc-4237	128	9	sex	sex	NOUN
dpc-4237	128	10	,	,	PUNCT
dpc-4237	128	11	disease	disease	NOUN
dpc-4237	128	12	severity	severity	NOUN
dpc-4237	128	13	,	,	PUNCT
dpc-4237	128	14	presence	presence	NOUN
dpc-4237	128	15	of	of	ADP
dpc-4237	128	16	angioedema	angioedema	SYM
dpc-4237	128	17	*	*	X
dpc-4237	128	18	.	.	PUNCT
dpc-4237	129	1	characteristic	characteristic	ADJ
dpc-4237	129	2	serum	serum	PROPN
dpc-4237	129	3	zonulin	zonulin	PROPN
dpc-4237	129	4	level	level	VERB
dpc-4237	129	5	p	p	NOUN
dpc-4237	129	6	-	-	PUNCT
dpc-4237	129	7	value	value	NOUN
dpc-4237	129	8	*	*	NOUN
dpc-4237	129	9	*	*	NOUN
dpc-4237	129	10	sex	sex	PROPN
dpc-4237	129	11	female(n	female(n	PROPN
dpc-4237	129	12	)	)	PUNCT
dpc-4237	129	13	33	33	NUM
dpc-4237	129	14	51.1	51.1	NUM
dpc-4237	129	15	(	(	PUNCT
dpc-4237	129	16	30.3	30.3	NUM
dpc-4237	129	17	-	-	SYM
dpc-4237	129	18	58.3	58.3	NUM
dpc-4237	129	19	)	)	PUNCT
dpc-4237	129	20	*	*	SYM
dpc-4237	129	21	0.006	0.006	NUM
dpc-4237	129	22	male	male	NOUN
dpc-4237	129	23	(	(	PUNCT
dpc-4237	129	24	n	n	CCONJ
dpc-4237	129	25	)	)	PUNCT
dpc-4237	129	26	30	30	NUM
dpc-4237	129	27	44.2	44.2	NUM
dpc-4237	129	28	(	(	PUNCT
dpc-4237	129	29	2.2	2.2	NUM
dpc-4237	129	30	-	-	SYM
dpc-4237	129	31	56.6	56.6	NUM
dpc-4237	129	32	)	)	PUNCT
dpc-4237	129	33	angioedema	angioedema	NOUN
dpc-4237	129	34	(	(	PUNCT
dpc-4237	129	35	+	+	NOUN
dpc-4237	129	36	)	)	PUNCT
dpc-4237	129	37	22	22	NUM
dpc-4237	129	38	51.6	51.6	NUM
dpc-4237	129	39	(	(	PUNCT
dpc-4237	129	40	30.8	30.8	NUM
dpc-4237	129	41	-	-	NUM
dpc-4237	129	42	58.3	58.3	NUM
dpc-4237	129	43	)	)	PUNCT
dpc-4237	129	44	*	*	PUNCT
dpc-4237	129	45	0.023	0.023	NUM
dpc-4237	129	46	(	(	PUNCT
dpc-4237	129	47	-	-	SYM
dpc-4237	129	48	)	)	PUNCT
dpc-4237	129	49	41	41	NUM
dpc-4237	129	50	47.5	47.5	NUM
dpc-4237	129	51	(	(	PUNCT
dpc-4237	129	52	2.2	2.2	NUM
dpc-4237	129	53	-	-	SYM
dpc-4237	129	54	56.6	56.6	NUM
dpc-4237	129	55	)	)	PUNCT
dpc-4237	129	56	uas7	uas7	NOUN
dpc-4237	130	1	well	well	ADV
dpc-4237	130	2	controlled	control	VERB
dpc-4237	130	3	11	11	NUM
dpc-4237	130	4	43.78	43.78	NUM
dpc-4237	130	5	±14.94	±14.94	NUM
dpc-4237	130	6	0.187	0.187	NUM
dpc-4237	130	7	mild	mild	ADJ
dpc-4237	130	8	urticaria	urticaria	NOUN
dpc-4237	130	9	22	22	NUM
dpc-4237	130	10	43.64±12.12	43.64±12.12	NUM
dpc-4237	130	11	severe	severe	ADJ
dpc-4237	130	12	activity	activity	NOUN
dpc-4237	130	13	urticaria	urticaria	NOUN
dpc-4237	130	14	30	30	NUM
dpc-4237	130	15	48.62±6.81	48.62±6.81	NOUN
dpc-4237	130	16	*	*	PUNCT
dpc-4237	130	17	mann	mann	PROPN
dpc-4237	130	18	-	-	PUNCT
dpc-4237	130	19	whitney	whitney	PROPN
dpc-4237	130	20	u	u	PROPN
dpc-4237	130	21	test	test	NOUN
dpc-4237	130	22	used	use	VERB
dpc-4237	130	23	for	for	ADP
dpc-4237	130	24	the	the	DET
dpc-4237	130	25	comparison	comparison	NOUN
dpc-4237	130	26	between	between	ADP
dpc-4237	130	27	study	study	NOUN
dpc-4237	130	28	groups	group	NOUN
dpc-4237	130	29	.	.	PUNCT
dpc-4237	131	1	*	*	PUNCT
dpc-4237	131	2	*	*	PUNCT
dpc-4237	131	3	significant	significant	ADJ
dpc-4237	131	4	p	p	NOUN
dpc-4237	131	5	-	-	PUNCT
dpc-4237	131	6	values	value	NOUN
dpc-4237	131	7	are	be	AUX
dpc-4237	131	8	marked	mark	VERB
dpc-4237	131	9	in	in	ADP
dpc-4237	131	10	bold	bold	ADJ
dpc-4237	131	11	;	;	PUNCT
dpc-4237	131	12	p<0.05	p<0.05	NOUN
dpc-4237	131	13	.	.	PUNCT
dpc-4237	131	14	original	original	ADJ
dpc-4237	131	15	article	article	NOUN
dpc-4237	131	16	|	|	ADV
dpc-4237	131	17	dermatol	dermatol	ADJ
dpc-4237	131	18	pract	pract	NOUN
dpc-4237	131	19	concept	concept	NOUN
dpc-4237	131	20	.	.	PUNCT
dpc-4237	132	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	132	2	5	5	NUM
dpc-4237	132	3	intestinal	intestinal	ADJ
dpc-4237	132	4	permeability	permeability	NOUN
dpc-4237	132	5	.	.	PUNCT
dpc-4237	133	1	additionally	additionally	ADV
dpc-4237	133	2	,	,	PUNCT
dpc-4237	133	3	as	as	ADP
dpc-4237	133	4	an	an	DET
dpc-4237	133	5	adjunct	adjunct	ADJ
dpc-4237	133	6	therapy	therapy	NOUN
dpc-4237	133	7	in	in	ADP
dpc-4237	133	8	the	the	DET
dpc-4237	133	9	management	management	NOUN
dpc-4237	133	10	of	of	ADP
dpc-4237	133	11	csus	csus	NOUN
dpc-4237	133	12	,	,	PUNCT
dpc-4237	133	13	interventions	intervention	NOUN
dpc-4237	133	14	that	that	PRON
dpc-4237	133	15	target	target	VERB
dpc-4237	133	16	intestinal	intestinal	ADJ
dpc-4237	133	17	permeability	permeability	NOUN
dpc-4237	133	18	such	such	ADJ
dpc-4237	133	19	as	as	ADP
dpc-4237	133	20	the	the	DET
dpc-4237	133	21	use	use	NOUN
dpc-4237	133	22	of	of	ADP
dpc-4237	133	23	probiotics	probiotic	NOUN
dpc-4237	133	24	,	,	PUNCT
dpc-4237	133	25	certain	certain	ADJ
dpc-4237	133	26	dietary	dietary	ADJ
dpc-4237	133	27	modifications	modification	NOUN
dpc-4237	133	28	,	,	PUNCT
dpc-4237	133	29	or	or	CCONJ
dpc-4237	133	30	pharmaceutical	pharmaceutical	NOUN
dpc-4237	133	31	drugs	drug	NOUN
dpc-4237	133	32	that	that	PRON
dpc-4237	133	33	are	be	AUX
dpc-4237	133	34	known	know	VERB
dpc-4237	133	35	to	to	PART
dpc-4237	133	36	increase	increase	VERB
dpc-4237	133	37	the	the	DET
dpc-4237	133	38	function	function	NOUN
dpc-4237	133	39	of	of	ADP
dpc-4237	133	40	the	the	DET
dpc-4237	133	41	gut	gut	NOUN
dpc-4237	133	42	barrier	barrier	NOUN
dpc-4237	133	43	might	might	AUX
dpc-4237	133	44	be	be	AUX
dpc-4237	133	45	investigated	investigate	VERB
dpc-4237	133	46	.	.	PUNCT
dpc-4237	134	1	this	this	DET
dpc-4237	134	2	method	method	NOUN
dpc-4237	134	3	recognizes	recognize	VERB
dpc-4237	134	4	the	the	DET
dpc-4237	134	5	connection	connection	NOUN
dpc-4237	134	6	between	between	ADP
dpc-4237	134	7	immunological	immunological	ADJ
dpc-4237	134	8	function	function	NOUN
dpc-4237	134	9	and	and	CCONJ
dpc-4237	134	10	gut	gut	NOUN
dpc-4237	134	11	health	health	NOUN
dpc-4237	134	12	and	and	CCONJ
dpc-4237	134	13	not	not	PART
dpc-4237	134	14	only	only	ADV
dpc-4237	134	15	provides	provide	VERB
dpc-4237	134	16	a	a	DET
dpc-4237	134	17	fresh	fresh	ADJ
dpc-4237	134	18	approach	approach	NOUN
dpc-4237	134	19	to	to	ADP
dpc-4237	134	20	treating	treat	VERB
dpc-4237	134	21	csu	csu	PROPN
dpc-4237	134	22	but	but	CCONJ
dpc-4237	134	23	also	also	ADV
dpc-4237	134	24	fits	fit	VERB
dpc-4237	134	25	with	with	ADP
dpc-4237	134	26	a	a	DET
dpc-4237	134	27	more	more	ADV
dpc-4237	134	28	comprehensive	comprehensive	ADJ
dpc-4237	134	29	understanding	understanding	NOUN
dpc-4237	134	30	of	of	ADP
dpc-4237	134	31	patient	patient	ADJ
dpc-4237	134	32	health	health	NOUN
dpc-4237	134	33	.	.	PUNCT
dpc-4237	135	1	however	however	ADV
dpc-4237	135	2	,	,	PUNCT
dpc-4237	135	3	it	it	PRON
dpc-4237	135	4	is	be	AUX
dpc-4237	135	5	important	important	ADJ
dpc-4237	135	6	to	to	PART
dpc-4237	135	7	note	note	VERB
dpc-4237	135	8	that	that	SCONJ
dpc-4237	135	9	,	,	PUNCT
dpc-4237	135	10	while	while	SCONJ
dpc-4237	135	11	our	our	PRON
dpc-4237	135	12	study	study	NOUN
dpc-4237	135	13	provides	provide	VERB
dpc-4237	135	14	a	a	DET
dpc-4237	135	15	promising	promising	ADJ
dpc-4237	135	16	direction	direction	NOUN
dpc-4237	135	17	,	,	PUNCT
dpc-4237	135	18	clinical	clinical	ADJ
dpc-4237	135	19	application	application	NOUN
dpc-4237	135	20	of	of	ADP
dpc-4237	135	21	these	these	DET
dpc-4237	135	22	findings	finding	NOUN
dpc-4237	135	23	should	should	AUX
dpc-4237	135	24	proceed	proceed	VERB
dpc-4237	135	25	with	with	ADP
dpc-4237	135	26	caution	caution	NOUN
dpc-4237	135	27	until	until	SCONJ
dpc-4237	135	28	further	further	ADJ
dpc-4237	135	29	research	research	NOUN
dpc-4237	135	30	corroborates	corroborate	VERB
dpc-4237	135	31	the	the	DET
dpc-4237	135	32	efficacy	efficacy	NOUN
dpc-4237	135	33	and	and	CCONJ
dpc-4237	135	34	safety	safety	NOUN
dpc-4237	135	35	of	of	ADP
dpc-4237	135	36	such	such	ADJ
dpc-4237	135	37	interventions	intervention	NOUN
dpc-4237	135	38	in	in	ADP
dpc-4237	135	39	csu	csu	PROPN
dpc-4237	135	40	patients	patient	NOUN
dpc-4237	135	41	.	.	PUNCT
dpc-4237	136	1	further	further	ADJ
dpc-4237	136	2	research	research	NOUN
dpc-4237	136	3	should	should	AUX
dpc-4237	136	4	explore	explore	VERB
dpc-4237	136	5	the	the	DET
dpc-4237	136	6	mechanisms	mechanism	NOUN
dpc-4237	136	7	linking	link	VERB
dpc-4237	136	8	serum	serum	NOUN
dpc-4237	136	9	zonulin	zonulin	PROPN
dpc-4237	136	10	levels	level	NOUN
dpc-4237	136	11	and	and	CCONJ
dpc-4237	136	12	csu	csu	VERB
dpc-4237	136	13	severity	severity	NOUN
dpc-4237	136	14	and	and	CCONJ
dpc-4237	136	15	examine	examine	VERB
dpc-4237	136	16	the	the	DET
dpc-4237	136	17	potential	potential	NOUN
dpc-4237	136	18	of	of	ADP
dpc-4237	136	19	adjusting	adjust	VERB
dpc-4237	136	20	intestinal	intestinal	ADJ
dpc-4237	136	21	permeability	permeability	NOUN
dpc-4237	136	22	as	as	ADP
dpc-4237	136	23	a	a	DET
dpc-4237	136	24	treatment	treatment	NOUN
dpc-4237	136	25	strategy	strategy	NOUN
dpc-4237	136	26	for	for	ADP
dpc-4237	136	27	csu	csu	PROPN
dpc-4237	136	28	.	.	PUNCT
dpc-4237	137	1	long	long	ADJ
dpc-4237	137	2	-	-	PUNCT
dpc-4237	137	3	term	term	NOUN
dpc-4237	137	4	studies	study	NOUN
dpc-4237	137	5	could	could	AUX
dpc-4237	137	6	provide	provide	VERB
dpc-4237	137	7	deeper	deep	ADJ
dpc-4237	137	8	insights	insight	NOUN
dpc-4237	137	9	into	into	ADP
dpc-4237	137	10	the	the	DET
dpc-4237	137	11	timing	timing	NOUN
dpc-4237	137	12	of	of	ADP
dpc-4237	137	13	intestinal	intestinal	ADJ
dpc-4237	137	14	permeability	permeability	NOUN
dpc-4237	137	15	changes	change	NOUN
dpc-4237	137	16	and	and	CCONJ
dpc-4237	137	17	csu	csu	VERB
dpc-4237	137	18	symptom	symptom	NOUN
dpc-4237	137	19	onset	onset	NOUN
dpc-4237	137	20	or	or	CCONJ
dpc-4237	137	21	exacerbation	exacerbation	NOUN
dpc-4237	137	22	.	.	PUNCT
dpc-4237	138	1	our	our	PRON
dpc-4237	138	2	research	research	NOUN
dpc-4237	138	3	lays	lay	VERB
dpc-4237	138	4	the	the	DET
dpc-4237	138	5	groundwork	groundwork	NOUN
dpc-4237	138	6	for	for	ADP
dpc-4237	138	7	a	a	DET
dpc-4237	138	8	fresh	fresh	ADJ
dpc-4237	138	9	understanding	understanding	NOUN
dpc-4237	138	10	of	of	ADP
dpc-4237	138	11	csu	csu	PROPN
dpc-4237	138	12	pathophysiology	pathophysiology	NOUN
dpc-4237	138	13	and	and	CCONJ
dpc-4237	138	14	suggests	suggest	VERB
dpc-4237	138	15	that	that	SCONJ
dpc-4237	138	16	intestinal	intestinal	ADJ
dpc-4237	138	17	permeability	permeability	NOUN
dpc-4237	138	18	is	be	AUX
dpc-4237	138	19	a	a	DET
dpc-4237	138	20	key	key	ADJ
dpc-4237	138	21	factor	factor	NOUN
dpc-4237	138	22	in	in	ADP
dpc-4237	138	23	the	the	DET
dpc-4237	138	24	disease	disease	NOUN
dpc-4237	138	25	’s	’s	PART
dpc-4237	138	26	course	course	NOUN
dpc-4237	138	27	.	.	PUNCT
dpc-4237	139	1	this	this	DET
dpc-4237	139	2	discovery	discovery	NOUN
dpc-4237	139	3	opens	open	VERB
dpc-4237	139	4	new	new	ADJ
dpc-4237	139	5	avenues	avenue	NOUN
dpc-4237	139	6	for	for	ADP
dpc-4237	139	7	future	future	ADJ
dpc-4237	139	8	studies	study	NOUN
dpc-4237	139	9	and	and	CCONJ
dpc-4237	139	10	potential	potential	ADJ
dpc-4237	139	11	treatments	treatment	NOUN
dpc-4237	139	12	,	,	PUNCT
dpc-4237	139	13	aimed	aim	VERB
dpc-4237	139	14	at	at	ADP
dpc-4237	139	15	improving	improve	VERB
dpc-4237	139	16	the	the	DET
dpc-4237	139	17	lives	life	NOUN
dpc-4237	139	18	of	of	ADP
dpc-4237	139	19	those	those	PRON
dpc-4237	139	20	suffering	suffer	VERB
dpc-4237	139	21	from	from	ADP
dpc-4237	139	22	this	this	DET
dpc-4237	139	23	chronic	chronic	NOUN
dpc-4237	139	24	and	and	CCONJ
dpc-4237	139	25	often	often	ADV
dpc-4237	139	26	debilitating	debilitate	VERB
dpc-4237	139	27	condition	condition	NOUN
dpc-4237	139	28	.	.	PUNCT
dpc-4237	140	1	limitations	limitation	NOUN
dpc-4237	140	2	it	it	PRON
dpc-4237	140	3	is	be	AUX
dpc-4237	140	4	crucial	crucial	ADJ
dpc-4237	140	5	to	to	PART
dpc-4237	140	6	acknowledge	acknowledge	VERB
dpc-4237	140	7	the	the	DET
dpc-4237	140	8	limitations	limitation	NOUN
dpc-4237	140	9	of	of	ADP
dpc-4237	140	10	our	our	PRON
dpc-4237	140	11	study	study	NOUN
dpc-4237	140	12	.	.	PUNCT
dpc-4237	141	1	the	the	DET
dpc-4237	141	2	results	result	NOUN
dpc-4237	141	3	of	of	ADP
dpc-4237	141	4	our	our	PRON
dpc-4237	141	5	study	study	NOUN
dpc-4237	141	6	may	may	AUX
dpc-4237	141	7	not	not	PART
dpc-4237	141	8	be	be	AUX
dpc-4237	141	9	broadly	broadly	ADV
dpc-4237	141	10	applicable	applicable	ADJ
dpc-4237	141	11	as	as	SCONJ
dpc-4237	141	12	they	they	PRON
dpc-4237	141	13	may	may	AUX
dpc-4237	141	14	be	be	AUX
dpc-4237	141	15	due	due	ADJ
dpc-4237	141	16	to	to	ADP
dpc-4237	141	17	the	the	DET
dpc-4237	141	18	small	small	ADJ
dpc-4237	141	19	sample	sample	NOUN
dpc-4237	141	20	size	size	NOUN
dpc-4237	141	21	and	and	CCONJ
dpc-4237	141	22	demographic	demographic	ADJ
dpc-4237	141	23	homogeneity	homogeneity	NOUN
dpc-4237	141	24	(	(	PUNCT
dpc-4237	141	25	all	all	DET
dpc-4237	141	26	turkish	turkish	ADJ
dpc-4237	141	27	participants	participant	NOUN
dpc-4237	141	28	came	come	VERB
dpc-4237	141	29	from	from	ADP
dpc-4237	141	30	the	the	DET
dpc-4237	141	31	same	same	ADJ
dpc-4237	141	32	area	area	NOUN
dpc-4237	141	33	)	)	PUNCT
dpc-4237	141	34	.	.	PUNCT
dpc-4237	142	1	to	to	PART
dpc-4237	142	2	confirm	confirm	VERB
dpc-4237	142	3	and	and	CCONJ
dpc-4237	142	4	build	build	VERB
dpc-4237	142	5	on	on	ADP
dpc-4237	142	6	our	our	PRON
dpc-4237	142	7	findings	finding	NOUN
dpc-4237	142	8	,	,	PUNCT
dpc-4237	142	9	larger	large	ADJ
dpc-4237	142	10	sample	sample	NOUN
dpc-4237	142	11	sizes	size	NOUN
dpc-4237	142	12	and	and	CCONJ
dpc-4237	142	13	a	a	DET
dpc-4237	142	14	more	more	ADV
dpc-4237	142	15	diverse	diverse	ADJ
dpc-4237	142	16	population	population	NOUN
dpc-4237	142	17	would	would	AUX
dpc-4237	142	18	be	be	AUX
dpc-4237	142	19	needed	need	VERB
dpc-4237	142	20	in	in	ADP
dpc-4237	142	21	future	future	ADJ
dpc-4237	142	22	research	research	NOUN
dpc-4237	142	23	.	.	PUNCT
dpc-4237	143	1	conclusion	conclusion	NOUN
dpc-4237	143	2	this	this	DET
dpc-4237	143	3	study	study	NOUN
dpc-4237	143	4	enhances	enhance	VERB
dpc-4237	143	5	our	our	PRON
dpc-4237	143	6	understanding	understanding	NOUN
dpc-4237	143	7	of	of	ADP
dpc-4237	143	8	csu	csu	VERB
dpc-4237	143	9	by	by	ADP
dpc-4237	143	10	demonstrating	demonstrate	VERB
dpc-4237	143	11	a	a	DET
dpc-4237	143	12	significant	significant	ADJ
dpc-4237	143	13	relationship	relationship	NOUN
dpc-4237	143	14	between	between	ADP
dpc-4237	143	15	elevated	elevate	VERB
dpc-4237	143	16	serum	serum	NOUN
dpc-4237	143	17	zonulin	zonulin	PROPN
dpc-4237	143	18	levels	level	NOUN
dpc-4237	143	19	and	and	CCONJ
dpc-4237	143	20	csu	csu	PROPN
dpc-4237	143	21	severity	severity	NOUN
dpc-4237	143	22	,	,	PUNCT
dpc-4237	143	23	especially	especially	ADV
dpc-4237	143	24	in	in	ADP
dpc-4237	143	25	patients	patient	NOUN
dpc-4237	143	26	with	with	ADP
dpc-4237	143	27	angioedema	angioedema	NOUN
dpc-4237	143	28	.	.	PUNCT
dpc-4237	144	1	these	these	DET
dpc-4237	144	2	results	result	NOUN
dpc-4237	144	3	highlight	highlight	VERB
dpc-4237	144	4	the	the	DET
dpc-4237	144	5	potential	potential	ADJ
dpc-4237	144	6	role	role	NOUN
dpc-4237	144	7	of	of	ADP
dpc-4237	144	8	intestinal	intestinal	ADJ
dpc-4237	144	9	permeability	permeability	NOUN
dpc-4237	144	10	in	in	ADP
dpc-4237	144	11	the	the	DET
dpc-4237	144	12	origin	origin	NOUN
dpc-4237	144	13	and	and	CCONJ
dpc-4237	144	14	progression	progression	NOUN
dpc-4237	144	15	of	of	ADP
dpc-4237	144	16	csu	csu	PROPN
dpc-4237	144	17	,	,	PUNCT
dpc-4237	144	18	offering	offer	VERB
dpc-4237	144	19	new	new	ADJ
dpc-4237	144	20	insights	insight	NOUN
dpc-4237	144	21	into	into	ADP
dpc-4237	144	22	its	its	PRON
dpc-4237	144	23	etiopathogenesis	etiopathogenesis	NOUN
dpc-4237	144	24	.	.	PUNCT
dpc-4237	145	1	our	our	PRON
dpc-4237	145	2	findings	finding	NOUN
dpc-4237	145	3	suggest	suggest	VERB
dpc-4237	145	4	that	that	SCONJ
dpc-4237	145	5	changes	change	NOUN
dpc-4237	145	6	in	in	ADP
dpc-4237	145	7	intestinal	intestinal	ADJ
dpc-4237	145	8	permeability	permeability	NOUN
dpc-4237	145	9	may	may	AUX
dpc-4237	145	10	influence	influence	VERB
dpc-4237	145	11	immune	immune	ADJ
dpc-4237	145	12	responses	response	NOUN
dpc-4237	145	13	in	in	ADP
dpc-4237	145	14	csu	csu	PROPN
dpc-4237	145	15	patients	patient	NOUN
dpc-4237	145	16	,	,	PUNCT
dpc-4237	145	17	pointing	point	VERB
dpc-4237	145	18	to	to	ADP
dpc-4237	145	19	new	new	ADJ
dpc-4237	145	20	therapeutic	therapeutic	ADJ
dpc-4237	145	21	approaches	approach	NOUN
dpc-4237	145	22	that	that	PRON
dpc-4237	145	23	target	target	VERB
dpc-4237	145	24	this	this	DET
dpc-4237	145	25	pathway	pathway	NOUN
dpc-4237	145	26	.	.	PUNCT
dpc-4237	146	1	patent	patent	NOUN
dpc-4237	146	2	consent	consent	NOUN
dpc-4237	146	3	:	:	PUNCT
dpc-4237	146	4	the	the	DET
dpc-4237	146	5	authors	author	NOUN
dpc-4237	146	6	acquired	acquire	VERB
dpc-4237	146	7	consent	consent	NOUN
dpc-4237	146	8	for	for	ADP
dpc-4237	146	9	the	the	DET
dpc-4237	146	10	publication	publication	NOUN
dpc-4237	146	11	of	of	ADP
dpc-4237	146	12	identifying	identify	VERB
dpc-4237	146	13	patient	patient	ADJ
dpc-4237	146	14	data	datum	NOUN
dpc-4237	146	15	or	or	CCONJ
dpc-4237	146	16	other	other	ADJ
dpc-4237	146	17	materials	material	NOUN
dpc-4237	146	18	,	,	PUNCT
dpc-4237	146	19	and	and	CCONJ
dpc-4237	146	20	included	include	VERB
dpc-4237	146	21	it	it	PRON
dpc-4237	146	22	with	with	ADP
dpc-4237	146	23	the	the	DET
dpc-4237	146	24	manuscript	manuscript	NOUN
dpc-4237	146	25	when	when	SCONJ
dpc-4237	146	26	they	they	PRON
dpc-4237	146	27	submitted	submit	VERB
dpc-4237	146	28	it	it	PRON
dpc-4237	146	29	to	to	ADP
dpc-4237	146	30	the	the	DET
dpc-4237	146	31	journal	journal	NOUN
dpc-4237	146	32	.	.	PUNCT
dpc-4237	147	1	the	the	DET
dpc-4237	147	2	consent	consent	NOUN
dpc-4237	147	3	stated	state	VERB
dpc-4237	147	4	that	that	SCONJ
dpc-4237	147	5	all	all	DET
dpc-4237	147	6	patients	patient	NOUN
dpc-4237	147	7	provided	provide	VERB
dpc-4237	147	8	their	their	PRON
dpc-4237	147	9	approval	approval	NOUN
dpc-4237	147	10	knowing	know	VERB
dpc-4237	147	11	that	that	SCONJ
dpc-4237	147	12	the	the	DET
dpc-4237	147	13	information	information	NOUN
dpc-4237	147	14	could	could	AUX
dpc-4237	147	15	be	be	AUX
dpc-4237	147	16	made	make	VERB
dpc-4237	147	17	public	public	ADJ
dpc-4237	147	18	.	.	PUNCT
dpc-4237	148	1	presentation	presentation	NOUN
dpc-4237	148	2	of	of	ADP
dpc-4237	148	3	these	these	DET
dpc-4237	148	4	diseases	disease	NOUN
dpc-4237	148	5	and	and	CCONJ
dpc-4237	148	6	may	may	AUX
dpc-4237	148	7	be	be	AUX
dpc-4237	148	8	related	relate	VERB
dpc-4237	148	9	to	to	ADP
dpc-4237	148	10	disease	disease	NOUN
dpc-4237	148	11	severity	severity	NOUN
dpc-4237	148	12	.	.	PUNCT
dpc-4237	149	1	drago	drago	AUX
dpc-4237	149	2	et	et	PROPN
dpc-4237	149	3	al	al	PROPN
dpc-4237	149	4	.	.	PROPN
dpc-4237	149	5	conducted	conduct	VERB
dpc-4237	149	6	an	an	DET
dpc-4237	149	7	ex	ex	X
dpc-4237	149	8	vivo	vivo	NOUN
dpc-4237	149	9	study	study	NOUN
dpc-4237	149	10	examining	examine	VERB
dpc-4237	149	11	duodenal	duodenal	ADJ
dpc-4237	149	12	biopsies	biopsy	NOUN
dpc-4237	149	13	from	from	ADP
dpc-4237	149	14	controls	control	NOUN
dpc-4237	149	15	and	and	CCONJ
dpc-4237	149	16	celiac	celiac	ADJ
dpc-4237	149	17	patients	patient	NOUN
dpc-4237	149	18	,	,	PUNCT
dpc-4237	149	19	finding	find	VERB
dpc-4237	149	20	that	that	SCONJ
dpc-4237	149	21	gliadin	gliadin	NOUN
dpc-4237	149	22	exposure	exposure	NOUN
dpc-4237	149	23	led	lead	VERB
dpc-4237	149	24	to	to	ADP
dpc-4237	149	25	a	a	DET
dpc-4237	149	26	brief	brief	ADJ
dpc-4237	149	27	increase	increase	NOUN
dpc-4237	149	28	in	in	ADP
dpc-4237	149	29	intestinal	intestinal	ADJ
dpc-4237	149	30	permeability	permeability	NOUN
dpc-4237	149	31	in	in	ADP
dpc-4237	149	32	both	both	DET
dpc-4237	149	33	groups	group	NOUN
dpc-4237	149	34	,	,	PUNCT
dpc-4237	149	35	with	with	ADP
dpc-4237	149	36	the	the	DET
dpc-4237	149	37	rise	rise	NOUN
dpc-4237	149	38	being	be	AUX
dpc-4237	149	39	more	more	ADV
dpc-4237	149	40	pronounced	pronounced	ADJ
dpc-4237	149	41	and	and	CCONJ
dpc-4237	149	42	resistant	resistant	ADJ
dpc-4237	149	43	in	in	ADP
dpc-4237	149	44	celiac	celiac	ADJ
dpc-4237	149	45	patients	patient	NOUN
dpc-4237	149	46	due	due	ADP
dpc-4237	149	47	to	to	ADP
dpc-4237	149	48	zonulin	zonulin	PROPN
dpc-4237	149	49	release	release	PROPN
dpc-4237	149	50	.	.	PUNCT
dpc-4237	150	1	this	this	PRON
dpc-4237	150	2	has	have	AUX
dpc-4237	150	3	prompted	prompt	VERB
dpc-4237	150	4	therapeutic	therapeutic	ADJ
dpc-4237	150	5	investigations	investigation	NOUN
dpc-4237	150	6	,	,	PUNCT
dpc-4237	150	7	such	such	ADJ
dpc-4237	150	8	as	as	ADP
dpc-4237	150	9	the	the	DET
dpc-4237	150	10	study	study	NOUN
dpc-4237	150	11	of	of	ADP
dpc-4237	150	12	larazotide	larazotide	PROPN
dpc-4237	150	13	acetate	acetate	NOUN
dpc-4237	150	14	,	,	PUNCT
dpc-4237	150	15	which	which	PRON
dpc-4237	150	16	blocks	block	VERB
dpc-4237	150	17	the	the	DET
dpc-4237	150	18	zonulin	zonulin	PROPN
dpc-4237	150	19	receptor	receptor	NOUN
dpc-4237	150	20	and	and	CCONJ
dpc-4237	150	21	is	be	AUX
dpc-4237	150	22	in	in	ADP
dpc-4237	150	23	phase	phase	NOUN
dpc-4237	150	24	iii	iii	NUM
dpc-4237	150	25	trials	trial	NOUN
dpc-4237	150	26	for	for	ADP
dpc-4237	150	27	treating	treat	VERB
dpc-4237	150	28	celiac	celiac	ADJ
dpc-4237	150	29	disease	disease	NOUN
dpc-4237	150	30	[	[	X
dpc-4237	150	31	10,14	10,14	ADP
dpc-4237	150	32	]	]	PUNCT
dpc-4237	150	33	.	.	PUNCT
dpc-4237	151	1	another	another	DET
dpc-4237	151	2	study	study	NOUN
dpc-4237	151	3	showed	show	VERB
dpc-4237	151	4	that	that	SCONJ
dpc-4237	151	5	gluten	gluten	NOUN
dpc-4237	151	6	-	-	PUNCT
dpc-4237	151	7	loaded	load	VERB
dpc-4237	151	8	celiac	celiac	ADJ
dpc-4237	151	9	patients	patient	NOUN
dpc-4237	151	10	treated	treat	VERB
dpc-4237	151	11	with	with	ADP
dpc-4237	151	12	larazotide	larazotide	PROPN
dpc-4237	151	13	acetate	acetate	PROPN
dpc-4237	151	14	experienced	experience	VERB
dpc-4237	151	15	a	a	DET
dpc-4237	151	16	decrease	decrease	NOUN
dpc-4237	151	17	in	in	ADP
dpc-4237	151	18	intestinal	intestinal	ADJ
dpc-4237	151	19	permeability	permeability	NOUN
dpc-4237	151	20	,	,	PUNCT
dpc-4237	151	21	symptoms	symptom	NOUN
dpc-4237	151	22	like	like	ADP
dpc-4237	151	23	diarrhea	diarrhea	NOUN
dpc-4237	151	24	and	and	CCONJ
dpc-4237	151	25	bloating	bloating	NOUN
dpc-4237	151	26	,	,	PUNCT
dpc-4237	151	27	and	and	CCONJ
dpc-4237	151	28	levels	level	NOUN
dpc-4237	151	29	of	of	ADP
dpc-4237	151	30	anti	anti	ADJ
dpc-4237	151	31	-	-	ADJ
dpc-4237	151	32	tissue	tissue	ADJ
dpc-4237	151	33	transglutaminase	transglutaminase	NOUN
dpc-4237	151	34	antibodies	antibodie	VERB
dpc-4237	151	35	and	and	CCONJ
dpc-4237	151	36	ifn	ifn	NOUN
dpc-4237	151	37	-	-	PUNCT
dpc-4237	151	38	γ	γ	NOUN
dpc-4237	151	39	[	[	X
dpc-4237	151	40	15	15	NUM
dpc-4237	151	41	]	]	PUNCT
dpc-4237	151	42	.	.	PUNCT
dpc-4237	152	1	animal	animal	NOUN
dpc-4237	152	2	experiments	experiment	NOUN
dpc-4237	152	3	have	have	AUX
dpc-4237	152	4	demonstrated	demonstrate	VERB
dpc-4237	152	5	that	that	SCONJ
dpc-4237	152	6	intestinal	intestinal	ADJ
dpc-4237	152	7	permeability	permeability	NOUN
dpc-4237	152	8	increases	increase	VERB
dpc-4237	152	9	in	in	ADP
dpc-4237	152	10	first	first	ADJ
dpc-4237	152	11	-	-	PUNCT
dpc-4237	152	12	degree	degree	NOUN
dpc-4237	152	13	relatives	relative	NOUN
dpc-4237	152	14	of	of	ADP
dpc-4237	152	15	irritable	irritable	ADJ
dpc-4237	152	16	bowel	bowel	NOUN
dpc-4237	152	17	disease	disease	NOUN
dpc-4237	152	18	(	(	PUNCT
dpc-4237	152	19	ibd	ibd	NOUN
dpc-4237	152	20	)	)	PUNCT
dpc-4237	152	21	patients	patient	NOUN
dpc-4237	152	22	even	even	ADV
dpc-4237	152	23	without	without	ADP
dpc-4237	152	24	ibd	ibd	PROPN
dpc-4237	152	25	and	and	CCONJ
dpc-4237	152	26	before	before	ADP
dpc-4237	152	27	its	its	PRON
dpc-4237	152	28	onset	onset	NOUN
dpc-4237	152	29	[	[	X
dpc-4237	152	30	16,17	16,17	NUM
dpc-4237	152	31	]	]	PUNCT
dpc-4237	152	32	.	.	PUNCT
dpc-4237	153	1	our	our	PRON
dpc-4237	153	2	research	research	NOUN
dpc-4237	153	3	suggests	suggest	VERB
dpc-4237	153	4	that	that	SCONJ
dpc-4237	153	5	patients	patient	NOUN
dpc-4237	153	6	with	with	ADP
dpc-4237	153	7	csu	csu	PROPN
dpc-4237	153	8	have	have	VERB
dpc-4237	153	9	higher	high	ADJ
dpc-4237	153	10	zonulin	zonulin	PROPN
dpc-4237	153	11	levels	level	NOUN
dpc-4237	153	12	than	than	ADP
dpc-4237	153	13	the	the	DET
dpc-4237	153	14	control	control	NOUN
dpc-4237	153	15	group	group	NOUN
dpc-4237	153	16	,	,	PUNCT
dpc-4237	153	17	indicating	indicate	VERB
dpc-4237	153	18	a	a	DET
dpc-4237	153	19	significant	significant	ADJ
dpc-4237	153	20	role	role	NOUN
dpc-4237	153	21	for	for	ADP
dpc-4237	153	22	increased	increase	VERB
dpc-4237	153	23	intestinal	intestinal	ADJ
dpc-4237	153	24	permeability	permeability	NOUN
dpc-4237	153	25	in	in	ADP
dpc-4237	153	26	the	the	DET
dpc-4237	153	27	pathophysiology	pathophysiology	NOUN
dpc-4237	153	28	of	of	ADP
dpc-4237	153	29	csu	csu	PROPN
dpc-4237	153	30	.	.	PUNCT
dpc-4237	154	1	however	however	ADV
dpc-4237	154	2	,	,	PUNCT
dpc-4237	154	3	serum	serum	PROPN
dpc-4237	154	4	zonulin	zonulin	PROPN
dpc-4237	154	5	levels	level	NOUN
dpc-4237	154	6	did	do	AUX
dpc-4237	154	7	not	not	PART
dpc-4237	154	8	correlate	correlate	VERB
dpc-4237	154	9	with	with	ADP
dpc-4237	154	10	disease	disease	NOUN
dpc-4237	154	11	severity	severity	NOUN
dpc-4237	154	12	,	,	PUNCT
dpc-4237	154	13	possibly	possibly	ADV
dpc-4237	154	14	due	due	ADP
dpc-4237	154	15	to	to	ADP
dpc-4237	154	16	insufficient	insufficient	ADJ
dpc-4237	154	17	patient	patient	ADJ
dpc-4237	154	18	numbers	number	NOUN
dpc-4237	154	19	in	in	ADP
dpc-4237	154	20	each	each	DET
dpc-4237	154	21	group	group	NOUN
dpc-4237	154	22	according	accord	VERB
dpc-4237	154	23	to	to	ADP
dpc-4237	154	24	uas7	uas7	PROPN
dpc-4237	154	25	.	.	PUNCT
dpc-4237	155	1	our	our	PRON
dpc-4237	155	2	study	study	NOUN
dpc-4237	155	3	found	find	VERB
dpc-4237	155	4	significantly	significantly	ADV
dpc-4237	155	5	higher	high	ADJ
dpc-4237	155	6	zonulin	zonulin	PROPN
dpc-4237	155	7	levels	level	NOUN
dpc-4237	155	8	in	in	ADP
dpc-4237	155	9	female	female	ADJ
dpc-4237	155	10	patients	patient	NOUN
dpc-4237	155	11	compared	compare	VERB
dpc-4237	155	12	to	to	ADP
dpc-4237	155	13	males	male	NOUN
dpc-4237	155	14	,	,	PUNCT
dpc-4237	155	15	a	a	DET
dpc-4237	155	16	connection	connection	NOUN
dpc-4237	155	17	not	not	PART
dpc-4237	155	18	previously	previously	ADV
dpc-4237	155	19	researched	research	VERB
dpc-4237	155	20	.	.	PUNCT
dpc-4237	156	1	this	this	PRON
dpc-4237	156	2	suggests	suggest	VERB
dpc-4237	156	3	that	that	SCONJ
dpc-4237	156	4	the	the	DET
dpc-4237	156	5	higher	high	ADJ
dpc-4237	156	6	incidence	incidence	NOUN
dpc-4237	156	7	of	of	ADP
dpc-4237	156	8	autoimmune	autoimmune	ADJ
dpc-4237	156	9	disorders	disorder	NOUN
dpc-4237	156	10	in	in	ADP
dpc-4237	156	11	females	female	NOUN
dpc-4237	156	12	might	might	AUX
dpc-4237	156	13	be	be	AUX
dpc-4237	156	14	linked	link	VERB
dpc-4237	156	15	to	to	ADP
dpc-4237	156	16	increased	increase	VERB
dpc-4237	156	17	intestinal	intestinal	ADJ
dpc-4237	156	18	permeability	permeability	NOUN
dpc-4237	156	19	[	[	X
dpc-4237	156	20	18	18	NUM
dpc-4237	156	21	]	]	PUNCT
dpc-4237	156	22	.	.	PUNCT
dpc-4237	157	1	nonetheless	nonetheless	ADV
dpc-4237	157	2	,	,	PUNCT
dpc-4237	157	3	male	male	ADJ
dpc-4237	157	4	csu	csu	NOUN
dpc-4237	157	5	patients	patient	NOUN
dpc-4237	157	6	also	also	ADV
dpc-4237	157	7	showed	show	VERB
dpc-4237	157	8	higher	high	ADJ
dpc-4237	157	9	zonulin	zonulin	NOUN
dpc-4237	157	10	levels	level	NOUN
dpc-4237	157	11	than	than	ADP
dpc-4237	157	12	the	the	DET
dpc-4237	157	13	control	control	NOUN
dpc-4237	157	14	group	group	NOUN
dpc-4237	157	15	,	,	PUNCT
dpc-4237	157	16	supporting	support	VERB
dpc-4237	157	17	zonulin	zonulin	PROPN
dpc-4237	157	18	’s	’s	PART
dpc-4237	157	19	involvement	involvement	NOUN
dpc-4237	157	20	in	in	ADP
dpc-4237	157	21	csu	csu	PROPN
dpc-4237	157	22	pathophysiology	pathophysiology	NOUN
dpc-4237	157	23	.	.	PUNCT
dpc-4237	158	1	in	in	ADP
dpc-4237	158	2	our	our	PRON
dpc-4237	158	3	investigation	investigation	NOUN
dpc-4237	158	4	,	,	PUNCT
dpc-4237	158	5	csu	csu	VERB
dpc-4237	158	6	patients	patient	NOUN
dpc-4237	158	7	with	with	ADP
dpc-4237	158	8	angioedema	angioedema	NOUN
dpc-4237	158	9	had	have	VERB
dpc-4237	158	10	considerably	considerably	ADV
dpc-4237	158	11	higher	high	ADJ
dpc-4237	158	12	serum	serum	NOUN
dpc-4237	158	13	zonulin	zonulin	PROPN
dpc-4237	158	14	levels	level	NOUN
dpc-4237	158	15	than	than	ADP
dpc-4237	158	16	those	those	PRON
dpc-4237	158	17	without	without	ADP
dpc-4237	158	18	,	,	PUNCT
dpc-4237	158	19	suggesting	suggest	VERB
dpc-4237	158	20	increased	increase	VERB
dpc-4237	158	21	intestinal	intestinal	ADJ
dpc-4237	158	22	permeability	permeability	NOUN
dpc-4237	158	23	.	.	PUNCT
dpc-4237	159	1	this	this	PRON
dpc-4237	159	2	could	could	AUX
dpc-4237	159	3	imply	imply	VERB
dpc-4237	159	4	that	that	SCONJ
dpc-4237	159	5	zonulin	zonulin	PROPN
dpc-4237	159	6	may	may	AUX
dpc-4237	159	7	also	also	ADV
dpc-4237	159	8	increase	increase	VERB
dpc-4237	159	9	vascular	vascular	ADJ
dpc-4237	159	10	permeability	permeability	NOUN
dpc-4237	159	11	,	,	PUNCT
dpc-4237	159	12	given	give	VERB
dpc-4237	159	13	that	that	SCONJ
dpc-4237	159	14	angioedema	angioedema	NOUN
dpc-4237	159	15	is	be	AUX
dpc-4237	159	16	associated	associate	VERB
dpc-4237	159	17	with	with	ADP
dpc-4237	159	18	increased	increase	VERB
dpc-4237	159	19	blood	blood	NOUN
dpc-4237	159	20	vessel	vessel	NOUN
dpc-4237	159	21	permeability	permeability	NOUN
dpc-4237	159	22	.	.	PUNCT
dpc-4237	160	1	although	although	SCONJ
dpc-4237	160	2	there	there	PRON
dpc-4237	160	3	is	be	VERB
dpc-4237	160	4	no	no	DET
dpc-4237	160	5	literature	literature	NOUN
dpc-4237	160	6	on	on	ADP
dpc-4237	160	7	zonulin	zonulin	PROPN
dpc-4237	160	8	’s	’s	PART
dpc-4237	160	9	effect	effect	NOUN
dpc-4237	160	10	on	on	ADP
dpc-4237	160	11	blood	blood	NOUN
dpc-4237	160	12	vessels	vessel	NOUN
dpc-4237	160	13	,	,	PUNCT
dpc-4237	160	14	one	one	NUM
dpc-4237	160	15	study	study	NOUN
dpc-4237	160	16	showed	show	VERB
dpc-4237	160	17	it	it	PRON
dpc-4237	160	18	regulates	regulate	VERB
dpc-4237	160	19	lymphatic	lymphatic	ADJ
dpc-4237	160	20	endothelial	endothelial	ADJ
dpc-4237	160	21	cell	cell	NOUN
dpc-4237	160	22	layer	layer	NOUN
dpc-4237	160	23	structure	structure	NOUN
dpc-4237	160	24	and	and	CCONJ
dpc-4237	160	25	permeability	permeability	NOUN
dpc-4237	160	26	[	[	X
dpc-4237	160	27	19	19	NUM
dpc-4237	160	28	]	]	PUNCT
dpc-4237	160	29	.	.	PUNCT
dpc-4237	161	1	the	the	DET
dpc-4237	161	2	literature	literature	NOUN
dpc-4237	161	3	has	have	AUX
dpc-4237	161	4	demonstrated	demonstrate	VERB
dpc-4237	161	5	that	that	SCONJ
dpc-4237	161	6	zonulin	zonulin	PROPN
dpc-4237	161	7	levels	level	NOUN
dpc-4237	161	8	may	may	AUX
dpc-4237	161	9	rise	rise	VERB
dpc-4237	161	10	before	before	ADP
dpc-4237	161	11	clinical	clinical	ADJ
dpc-4237	161	12	manifestation	manifestation	NOUN
dpc-4237	161	13	[	[	X
dpc-4237	161	14	17	17	NUM
dpc-4237	161	15	]	]	PUNCT
dpc-4237	161	16	.	.	PUNCT
dpc-4237	162	1	in	in	ADP
dpc-4237	162	2	light	light	NOUN
dpc-4237	162	3	of	of	ADP
dpc-4237	162	4	our	our	PRON
dpc-4237	162	5	findings	finding	NOUN
dpc-4237	162	6	,	,	PUNCT
dpc-4237	162	7	the	the	DET
dpc-4237	162	8	hypothesis	hypothesis	NOUN
dpc-4237	162	9	that	that	PRON
dpc-4237	162	10	a	a	DET
dpc-4237	162	11	patient	patient	NOUN
dpc-4237	162	12	’s	’s	PART
dpc-4237	162	13	elevated	elevated	ADJ
dpc-4237	162	14	zonulin	zonulin	NOUN
dpc-4237	162	15	level	level	NOUN
dpc-4237	162	16	could	could	AUX
dpc-4237	162	17	signal	signal	VERB
dpc-4237	162	18	the	the	DET
dpc-4237	162	19	onset	onset	NOUN
dpc-4237	162	20	of	of	ADP
dpc-4237	162	21	angioedema	angioedema	ADV
dpc-4237	162	22	becomes	become	VERB
dpc-4237	162	23	more	more	ADV
dpc-4237	162	24	compelling	compelling	ADJ
dpc-4237	162	25	.	.	PUNCT
dpc-4237	163	1	on	on	ADP
dpc-4237	163	2	the	the	DET
dpc-4237	163	3	other	other	ADJ
dpc-4237	163	4	hand	hand	NOUN
dpc-4237	163	5	,	,	PUNCT
dpc-4237	163	6	the	the	DET
dpc-4237	163	7	findings	finding	NOUN
dpc-4237	163	8	of	of	ADP
dpc-4237	163	9	this	this	DET
dpc-4237	163	10	study	study	NOUN
dpc-4237	163	11	have	have	VERB
dpc-4237	163	12	major	major	ADJ
dpc-4237	163	13	therapeutic	therapeutic	ADJ
dpc-4237	163	14	implications	implication	NOUN
dpc-4237	163	15	for	for	ADP
dpc-4237	163	16	the	the	DET
dpc-4237	163	17	management	management	NOUN
dpc-4237	163	18	and	and	CCONJ
dpc-4237	163	19	therapy	therapy	NOUN
dpc-4237	163	20	of	of	ADP
dpc-4237	163	21	csu	csu	PROPN
dpc-4237	163	22	.	.	PUNCT
dpc-4237	164	1	the	the	DET
dpc-4237	164	2	correlation	correlation	NOUN
dpc-4237	164	3	that	that	PRON
dpc-4237	164	4	has	have	AUX
dpc-4237	164	5	been	be	AUX
dpc-4237	164	6	discovered	discover	VERB
dpc-4237	164	7	between	between	ADP
dpc-4237	164	8	the	the	DET
dpc-4237	164	9	severity	severity	NOUN
dpc-4237	164	10	of	of	ADP
dpc-4237	164	11	csu	csu	PROPN
dpc-4237	164	12	and	and	CCONJ
dpc-4237	164	13	elevated	elevate	VERB
dpc-4237	164	14	serum	serum	PROPN
dpc-4237	164	15	zonulin	zonulin	PROPN
dpc-4237	164	16	levels	level	NOUN
dpc-4237	164	17	,	,	PUNCT
dpc-4237	164	18	especially	especially	ADV
dpc-4237	164	19	in	in	ADP
dpc-4237	164	20	patients	patient	NOUN
dpc-4237	164	21	with	with	ADP
dpc-4237	164	22	angioedema	angioedema	NOUN
dpc-4237	164	23	,	,	PUNCT
dpc-4237	164	24	implies	imply	VERB
dpc-4237	164	25	that	that	SCONJ
dpc-4237	164	26	intestinal	intestinal	ADJ
dpc-4237	164	27	permeability	permeability	NOUN
dpc-4237	164	28	may	may	AUX
dpc-4237	164	29	play	play	VERB
dpc-4237	164	30	a	a	DET
dpc-4237	164	31	crucial	crucial	ADJ
dpc-4237	164	32	role	role	NOUN
dpc-4237	164	33	in	in	ADP
dpc-4237	164	34	the	the	DET
dpc-4237	164	35	worsening	worsening	NOUN
dpc-4237	164	36	of	of	ADP
dpc-4237	164	37	the	the	DET
dpc-4237	164	38	condition	condition	NOUN
dpc-4237	164	39	.	.	PUNCT
dpc-4237	165	1	this	this	DET
dpc-4237	165	2	realization	realization	NOUN
dpc-4237	165	3	makes	make	VERB
dpc-4237	165	4	room	room	NOUN
dpc-4237	165	5	for	for	ADP
dpc-4237	165	6	cutting	cut	VERB
dpc-4237	165	7	-	-	PUNCT
dpc-4237	165	8	edge	edge	NOUN
dpc-4237	165	9	treatment	treatment	NOUN
dpc-4237	165	10	strategies	strategy	NOUN
dpc-4237	165	11	that	that	PRON
dpc-4237	165	12	focus	focus	VERB
dpc-4237	165	13	on	on	ADP
dpc-4237	165	14	gut	gut	NOUN
dpc-4237	165	15	integrity	integrity	NOUN
dpc-4237	165	16	and	and	CCONJ
dpc-4237	165	17	health	health	NOUN
dpc-4237	165	18	.	.	PUNCT
dpc-4237	166	1	when	when	SCONJ
dpc-4237	166	2	doing	do	VERB
dpc-4237	166	3	a	a	DET
dpc-4237	166	4	thorough	thorough	ADJ
dpc-4237	166	5	diagnostic	diagnostic	ADJ
dpc-4237	166	6	workup	workup	NOUN
dpc-4237	166	7	on	on	ADP
dpc-4237	166	8	csu	csu	PROPN
dpc-4237	166	9	patients	patient	NOUN
dpc-4237	166	10	,	,	PUNCT
dpc-4237	166	11	clinicians	clinician	NOUN
dpc-4237	166	12	may	may	AUX
dpc-4237	166	13	want	want	VERB
dpc-4237	166	14	to	to	PART
dpc-4237	166	15	assess	assess	VERB
dpc-4237	166	16	6	6	NUM
dpc-4237	166	17	original	original	ADJ
dpc-4237	166	18	article	article	NOUN
dpc-4237	166	19	|	|	ADV
dpc-4237	166	20	dermatol	dermatol	ADJ
dpc-4237	166	21	pract	pract	NOUN
dpc-4237	166	22	concept	concept	NOUN
dpc-4237	166	23	.	.	PUNCT
dpc-4237	167	1	2025;15(1):4237	2025;15(1):4237	NUM
dpc-4237	167	2	11	11	NUM
dpc-4237	167	3	.	.	PUNCT
dpc-4237	168	1	asmar	asmar	PROPN
dpc-4237	168	2	rel	rel	PROPN
dpc-4237	168	3	,	,	PUNCT
dpc-4237	168	4	panigrahi	panigrahi	NOUN
dpc-4237	168	5	p	p	NOUN
dpc-4237	168	6	,	,	PUNCT
dpc-4237	168	7	bamford	bamford	PROPN
dpc-4237	168	8	p	p	PROPN
dpc-4237	168	9	,	,	PUNCT
dpc-4237	168	10	et	et	PROPN
dpc-4237	168	11	al	al	PROPN
dpc-4237	168	12	.	.	PROPN
dpc-4237	168	13	host	host	NOUN
dpc-4237	168	14	-	-	PUNCT
dpc-4237	168	15	dependent	dependent	ADJ
dpc-4237	168	16	zonulin	zonulin	PROPN
dpc-4237	168	17	secretion	secretion	NOUN
dpc-4237	168	18	causes	cause	VERB
dpc-4237	168	19	the	the	DET
dpc-4237	168	20	impairment	impairment	NOUN
dpc-4237	168	21	of	of	ADP
dpc-4237	168	22	the	the	DET
dpc-4237	168	23	small	small	ADJ
dpc-4237	168	24	intestine	intestine	NOUN
dpc-4237	168	25	barrier	barrier	NOUN
dpc-4237	168	26	function	function	NOUN
dpc-4237	168	27	after	after	ADP
dpc-4237	168	28	bacterial	bacterial	ADJ
dpc-4237	168	29	exposure	exposure	NOUN
dpc-4237	168	30	.	.	PUNCT
dpc-4237	169	1	gastroenterology	gastroenterology	NOUN
dpc-4237	169	2	.	.	PUNCT
dpc-4237	170	1	2002;123(5):1607–1615	2002;123(5):1607–1615	NUM
dpc-4237	170	2	.	.	PUNCT
dpc-4237	170	3	doi	doi	NOUN
dpc-4237	170	4	:	:	PUNCT
dpc-4237	170	5	10.1053	10.1053	NUM
dpc-4237	170	6	/	/	SYM
dpc-4237	170	7	gast.2002.36578	gast.2002.36578	PROPN
dpc-4237	170	8	.	.	PUNCT
dpc-4237	171	1	12	12	NUM
dpc-4237	171	2	.	.	PUNCT
dpc-4237	171	3	fasano	fasano	PROPN
dpc-4237	171	4	a.	a.	PROPN
dpc-4237	171	5	zonulin	zonulin	PROPN
dpc-4237	171	6	and	and	CCONJ
dpc-4237	171	7	its	its	PRON
dpc-4237	171	8	regulation	regulation	NOUN
dpc-4237	171	9	of	of	ADP
dpc-4237	171	10	intestinal	intestinal	ADJ
dpc-4237	171	11	barrier	barrier	NOUN
dpc-4237	171	12	function	function	NOUN
dpc-4237	171	13	:	:	PUNCT
dpc-4237	171	14	the	the	DET
dpc-4237	171	15	biological	biological	ADJ
dpc-4237	171	16	door	door	NOUN
dpc-4237	171	17	to	to	ADP
dpc-4237	171	18	inflammation	inflammation	NOUN
dpc-4237	171	19	,	,	PUNCT
dpc-4237	171	20	autoimmunity	autoimmunity	NOUN
dpc-4237	171	21	,	,	PUNCT
dpc-4237	171	22	and	and	CCONJ
dpc-4237	171	23	cancer	cancer	NOUN
dpc-4237	171	24	.	.	PUNCT
dpc-4237	172	1	physiol	physiol	PROPN
dpc-4237	172	2	rev	rev	VERB
dpc-4237	172	3	.	.	PROPN
dpc-4237	172	4	2011;151–175	2011;151–175	NUM
dpc-4237	172	5	.	.	PUNCT
dpc-4237	173	1	doi	doi	NOUN
dpc-4237	173	2	:	:	PUNCT
dpc-4237	173	3	10.1152	10.1152	NUM
dpc-4237	173	4	/	/	SYM
dpc-4237	173	5	physrev.00003	physrev.00003	PROPN
dpc-4237	173	6	.2008	.2008	NOUN
dpc-4237	173	7	.	.	PUNCT
dpc-4237	174	1	13	13	NUM
dpc-4237	174	2	.	.	PUNCT
dpc-4237	175	1	drago	drago	PROPN
dpc-4237	175	2	s	s	PROPN
dpc-4237	175	3	,	,	PUNCT
dpc-4237	175	4	asmar	asmar	PROPN
dpc-4237	175	5	rel	rel	PROPN
dpc-4237	175	6	,	,	PUNCT
dpc-4237	175	7	pierro	pierro	PROPN
dpc-4237	175	8	mdi	mdi	PROPN
dpc-4237	175	9	,	,	PUNCT
dpc-4237	175	10	et	et	PROPN
dpc-4237	175	11	al	al	PROPN
dpc-4237	175	12	.	.	PUNCT
dpc-4237	176	1	gliadin	gliadin	NOUN
dpc-4237	176	2	,	,	PUNCT
dpc-4237	176	3	zonulin	zonulin	NOUN
dpc-4237	176	4	and	and	CCONJ
dpc-4237	176	5	gut	gut	NOUN
dpc-4237	176	6	permeability	permeability	NOUN
dpc-4237	176	7	:	:	PUNCT
dpc-4237	176	8	effects	effect	NOUN
dpc-4237	176	9	on	on	ADP
dpc-4237	176	10	celiac	celiac	ADJ
dpc-4237	176	11	and	and	CCONJ
dpc-4237	176	12	non	non	ADJ
dpc-4237	176	13	-	-	ADJ
dpc-4237	176	14	celiac	celiac	ADJ
dpc-4237	176	15	intestinal	intestinal	ADJ
dpc-4237	176	16	mucosa	mucosa	NOUN
dpc-4237	176	17	and	and	CCONJ
dpc-4237	176	18	intestinal	intestinal	ADJ
dpc-4237	176	19	cell	cell	NOUN
dpc-4237	176	20	lines	line	NOUN
dpc-4237	176	21	.	.	PUNCT
dpc-4237	177	1	scand	scand	PROPN
dpc-4237	177	2	j	j	PROPN
dpc-4237	177	3	gastroenterol	gastroenterol	PROPN
dpc-4237	177	4	.	.	PUNCT
dpc-4237	178	1	2006;(3	2006;(3	NUM
dpc-4237	178	2	):	):	PUNCT
dpc-4237	179	1	408–419	408–419	NUM
dpc-4237	179	2	.	.	PUNCT
dpc-4237	180	1	doi	doi	NOUN
dpc-4237	180	2	:	:	PUNCT
dpc-4237	180	3	10.1080/00365520500235334	10.1080/00365520500235334	NUM
dpc-4237	180	4	.	.	PUNCT
dpc-4237	181	1	14	14	NUM
dpc-4237	181	2	.	.	X
dpc-4237	181	3	paterson	paterson	PROPN
dpc-4237	181	4	bm	bm	PROPN
dpc-4237	181	5	,	,	PUNCT
dpc-4237	181	6	lammers	lammers	PROPN
dpc-4237	181	7	km	km	PROPN
dpc-4237	181	8	,	,	PUNCT
dpc-4237	181	9	arrieta	arrieta	PROPN
dpc-4237	181	10	mc	mc	PROPN
dpc-4237	181	11	,	,	PUNCT
dpc-4237	181	12	fasano	fasano	PROPN
dpc-4237	181	13	a	a	X
dpc-4237	181	14	,	,	PUNCT
dpc-4237	181	15	meddings	medding	NOUN
dpc-4237	181	16	jb	jb	PROPN
dpc-4237	181	17	.	.	PUNCT
dpc-4237	182	1	the	the	DET
dpc-4237	182	2	safety	safety	NOUN
dpc-4237	182	3	,	,	PUNCT
dpc-4237	182	4	tolerance	tolerance	NOUN
dpc-4237	182	5	,	,	PUNCT
dpc-4237	182	6	pharmacokinetic	pharmacokinetic	ADJ
dpc-4237	182	7	and	and	CCONJ
dpc-4237	182	8	pharmacodynamic	pharmacodynamic	ADJ
dpc-4237	182	9	effects	effect	NOUN
dpc-4237	182	10	of	of	ADP
dpc-4237	182	11	single	single	ADJ
dpc-4237	182	12	doses	dose	NOUN
dpc-4237	182	13	of	of	ADP
dpc-4237	182	14	at-1001	at-1001	NOUN
dpc-4237	182	15	in	in	ADP
dpc-4237	182	16	coeliac	coeliac	NOUN
dpc-4237	182	17	disease	disease	NOUN
dpc-4237	182	18	subjects	subject	NOUN
dpc-4237	182	19	:	:	PUNCT
dpc-4237	182	20	a	a	DET
dpc-4237	182	21	proof	proof	NOUN
dpc-4237	182	22	of	of	ADP
dpc-4237	182	23	concept	concept	NOUN
dpc-4237	182	24	study	study	NOUN
dpc-4237	182	25	.	.	PUNCT
dpc-4237	183	1	aliment	aliment	NOUN
dpc-4237	183	2	pharmacol	pharmacol	VERB
dpc-4237	183	3	ther	ther	ADV
dpc-4237	183	4	.	.	PUNCT
dpc-4237	184	1	2007;(6):757–766	2007;(6):757–766	NUM
dpc-4237	184	2	.	.	PUNCT
dpc-4237	185	1	doi	doi	NOUN
dpc-4237	185	2	:	:	PUNCT
dpc-4237	185	3	10.1111	10.1111	NUM
dpc-4237	185	4	/	/	SYM
dpc-4237	185	5	j.1365	j.1365	NOUN
dpc-4237	185	6	-	-	PUNCT
dpc-4237	185	7	2036.2007	2036.2007	NOUN
dpc-4237	185	8	.	.	PUNCT
dpc-4237	186	1	03413.x	03413.x	NOUN
dpc-4237	186	2	.	.	PUNCT
dpc-4237	187	1	15	15	NUM
dpc-4237	187	2	.	.	PUNCT
dpc-4237	188	1	heickman	heickman	ADJ
dpc-4237	188	2	lkw	lkw	PROPN
dpc-4237	188	3	,	,	PUNCT
dpc-4237	188	4	deboer	deboer	PROPN
dpc-4237	188	5	md	md	PROPN
dpc-4237	188	6	,	,	PUNCT
dpc-4237	188	7	fasano	fasano	PROPN
dpc-4237	188	8	a.	a.	PROPN
dpc-4237	188	9	zonulin	zonulin	PROPN
dpc-4237	188	10	as	as	ADP
dpc-4237	188	11	a	a	DET
dpc-4237	188	12	potential	potential	ADJ
dpc-4237	188	13	putative	putative	ADJ
dpc-4237	188	14	biomarker	biomarker	NOUN
dpc-4237	188	15	of	of	ADP
dpc-4237	188	16	risk	risk	NOUN
dpc-4237	188	17	for	for	ADP
dpc-4237	188	18	shared	shared	ADJ
dpc-4237	188	19	type	type	NOUN
dpc-4237	188	20	1	1	NUM
dpc-4237	188	21	diabetes	diabetes	NOUN
dpc-4237	188	22	and	and	CCONJ
dpc-4237	188	23	celiac	celiac	ADJ
dpc-4237	188	24	disease	disease	NOUN
dpc-4237	188	25	autoimmunity	autoimmunity	NOUN
dpc-4237	188	26	.	.	PUNCT
dpc-4237	189	1	diabetes	diabetes	NOUN
dpc-4237	189	2	metab	metab	NOUN
dpc-4237	189	3	res	re	NOUN
dpc-4237	189	4	rev	rev	PROPN
dpc-4237	189	5	.	.	PROPN
dpc-4237	190	1	2020;(12):1–14	2020;(12):1–14	NUM
dpc-4237	190	2	.	.	PUNCT
dpc-4237	191	1	doi	doi	NOUN
dpc-4237	191	2	:	:	PUNCT
dpc-4237	191	3	10.1002	10.1002	NUM
dpc-4237	191	4	/	/	SYM
dpc-4237	191	5	dmrr.3309	dmrr.3309	NOUN
dpc-4237	191	6	.	.	PUNCT
dpc-4237	191	7	  	  	SPACE
dpc-4237	191	8	16	16	NUM
dpc-4237	191	9	.	.	PUNCT
dpc-4237	192	1	madsen	madsen	PROPN
dpc-4237	192	2	kl	kl	PROPN
dpc-4237	192	3	,	,	PUNCT
dpc-4237	192	4	malfair	malfair	PROPN
dpc-4237	192	5	d	d	PROPN
dpc-4237	192	6	,	,	PUNCT
dpc-4237	192	7	gray	gray	ADJ
dpc-4237	192	8	d	d	NOUN
dpc-4237	192	9	,	,	PUNCT
dpc-4237	192	10	doyle	doyle	PROPN
dpc-4237	192	11	js	js	PROPN
dpc-4237	192	12	,	,	PUNCT
dpc-4237	192	13	jewell	jewell	PROPN
dpc-4237	192	14	ld	ld	PROPN
dpc-4237	192	15	,	,	PUNCT
dpc-4237	192	16	fedorak	fedorak	PROPN
dpc-4237	192	17	rn	rn	PROPN
dpc-4237	192	18	.	.	PROPN
dpc-4237	192	19	interleukin10	interleukin10	PROPN
dpc-4237	192	20	gene	gene	NOUN
dpc-4237	192	21	-	-	PUNCT
dpc-4237	192	22	deficient	deficient	ADJ
dpc-4237	192	23	mice	mouse	NOUN
dpc-4237	192	24	develop	develop	VERB
dpc-4237	192	25	a	a	DET
dpc-4237	192	26	primary	primary	ADJ
dpc-4237	192	27	intestinal	intestinal	ADJ
dpc-4237	192	28	permeability	permeability	NOUN
dpc-4237	192	29	defect	defect	NOUN
dpc-4237	192	30	in	in	ADP
dpc-4237	192	31	response	response	NOUN
dpc-4237	192	32	to	to	ADP
dpc-4237	192	33	enteric	enteric	ADJ
dpc-4237	192	34	microflora	microflora	NOUN
dpc-4237	192	35	.	.	PUNCT
dpc-4237	193	1	inflamm	inflamm	PROPN
dpc-4237	193	2	bowel	bowel	PROPN
dpc-4237	193	3	dis	dis	PROPN
dpc-4237	193	4	.	.	PUNCT
dpc-4237	194	1	1999;5(4):262–270	1999;5(4):262–270	X
dpc-4237	194	2	.	.	PUNCT
dpc-4237	195	1	doi	doi	NOUN
dpc-4237	195	2	:	:	PUNCT
dpc-4237	195	3	10.1097	10.1097	NUM
dpc-4237	195	4	/00054725	/00054725	SYM
dpc-4237	195	5	-	-	SYM
dpc-4237	195	6	199911000	199911000	NUM
dpc-4237	195	7	-	-	SYM
dpc-4237	195	8	00004	00004	NUM
dpc-4237	195	9	.	.	PUNCT
dpc-4237	196	1	17	17	NUM
dpc-4237	196	2	.	.	PUNCT
dpc-4237	197	1	peeters	peeter	NOUN
dpc-4237	197	2	m	m	PROPN
dpc-4237	197	3	,	,	PUNCT
dpc-4237	197	4	geypens	geypen	VERB
dpc-4237	197	5	b	b	NUM
dpc-4237	197	6	,	,	PUNCT
dpc-4237	197	7	claus	claus	NOUN
dpc-4237	197	8	d	d	PROPN
dpc-4237	197	9	,	,	PUNCT
dpc-4237	197	10	et	et	PROPN
dpc-4237	197	11	al	al	PROPN
dpc-4237	197	12	.	.	PROPN
dpc-4237	198	1	clustering	clustering	NOUN
dpc-4237	198	2	of	of	ADP
dpc-4237	198	3	increased	increase	VERB
dpc-4237	198	4	small	small	ADJ
dpc-4237	198	5	intestinal	intestinal	ADJ
dpc-4237	198	6	permeability	permeability	NOUN
dpc-4237	198	7	in	in	ADP
dpc-4237	198	8	families	family	NOUN
dpc-4237	198	9	with	with	ADP
dpc-4237	198	10	crohn	crohn	PROPN
dpc-4237	198	11	’s	’s	PART
dpc-4237	198	12	disease	disease	NOUN
dpc-4237	198	13	.	.	PUNCT
dpc-4237	199	1	gastroenterology	gastroenterology	NOUN
dpc-4237	199	2	.	.	PUNCT
dpc-4237	200	1	1997;113(3):802–807	1997;113(3):802–807	NUM
dpc-4237	200	2	.	.	PUNCT
dpc-4237	200	3	doi	doi	NOUN
dpc-4237	200	4	:	:	PUNCT
dpc-4237	200	5	10.1016	10.1016	NUM
dpc-4237	200	6	/	/	SYM
dpc-4237	200	7	s0016	s0016	PROPN
dpc-4237	200	8	-5085(97)70174	-5085(97)70174	PROPN
dpc-4237	200	9	-	-	PUNCT
dpc-4237	200	10	4	4	NUM
dpc-4237	200	11	18	18	NUM
dpc-4237	200	12	.	.	PUNCT
dpc-4237	201	1	moulton	moulton	PROPN
dpc-4237	201	2	v.	v.	ADP
dpc-4237	201	3	sex	sex	NOUN
dpc-4237	201	4	hormones	hormone	NOUN
dpc-4237	201	5	in	in	ADP
dpc-4237	201	6	acquired	acquire	VERB
dpc-4237	201	7	immunity	immunity	NOUN
dpc-4237	201	8	and	and	CCONJ
dpc-4237	201	9	autoimmune	autoimmune	ADJ
dpc-4237	201	10	disease	disease	NOUN
dpc-4237	201	11	.	.	PUNCT
dpc-4237	202	1	front	front	ADJ
dpc-4237	202	2	immunol	immunol	NOUN
dpc-4237	202	3	.	.	PUNCT
dpc-4237	203	1	2018;9:2279	2018;9:2279	NOUN
dpc-4237	203	2	.	.	PUNCT
dpc-4237	204	1	doi	doi	NOUN
dpc-4237	204	2	:	:	PUNCT
dpc-4237	204	3	10.3389	10.3389	NUM
dpc-4237	204	4	/fimmu.2018.02279	/fimmu.2018.02279	NOUN
dpc-4237	204	5	.	.	PUNCT
dpc-4237	204	6	  	  	SPACE
dpc-4237	205	1	19	19	NUM
dpc-4237	205	2	.	.	PUNCT
dpc-4237	206	1	xiong	xiong	PROPN
dpc-4237	206	2	y	y	PROPN
dpc-4237	206	3	,	,	PUNCT
dpc-4237	206	4	piao	piao	NOUN
dpc-4237	206	5	w	w	PROPN
dpc-4237	206	6	,	,	PUNCT
dpc-4237	206	7	brinkman	brinkman	PROPN
dpc-4237	206	8	cc	cc	PROPN
dpc-4237	206	9	,	,	PUNCT
dpc-4237	206	10	et	et	PROPN
dpc-4237	206	11	al	al	PROPN
dpc-4237	206	12	.	.	PUNCT
dpc-4237	207	1	cd4	cd4	PROPN
dpc-4237	207	2	t	t	PROPN
dpc-4237	207	3	cell	cell	NOUN
dpc-4237	207	4	sphingosine	sphingosine	NOUN
dpc-4237	207	5	1	1	NUM
dpc-4237	207	6	-	-	PUNCT
dpc-4237	207	7	phosphate	phosphate	NOUN
dpc-4237	207	8	receptor	receptor	NOUN
dpc-4237	207	9	(	(	PUNCT
dpc-4237	207	10	s1pr	s1pr	PUNCT
dpc-4237	207	11	)	)	PUNCT
dpc-4237	207	12	1	1	NUM
dpc-4237	207	13	and	and	CCONJ
dpc-4237	207	14	s1pr4	s1pr4	NOUN
dpc-4237	207	15	and	and	CCONJ
dpc-4237	207	16	endothelial	endothelial	NOUN
dpc-4237	207	17	s1pr2	s1pr2	NOUN
dpc-4237	207	18	regulate	regulate	VERB
dpc-4237	207	19	afferent	afferent	ADJ
dpc-4237	207	20	lymphatic	lymphatic	ADJ
dpc-4237	207	21	migration	migration	NOUN
dpc-4237	207	22	.	.	PUNCT
dpc-4237	208	1	sci	sci	PROPN
dpc-4237	208	2	immunol	immunol	NOUN
dpc-4237	208	3	.	.	PUNCT
dpc-4237	209	1	2019;1263(3	2019;1263(3	NUM
dpc-4237	209	2	)	)	PUNCT
dpc-4237	209	3	.	.	PUNCT
dpc-4237	210	1	doi	doi	NOUN
dpc-4237	210	2	:	:	PUNCT
dpc-4237	210	3	10.1126	10.1126	NUM
dpc-4237	210	4	/	/	SYM
dpc-4237	210	5	sciimmunol.aav1263	sciimmunol.aav1263	PUNCT
dpc-4237	210	6	.	.	PUNCT
dpc-4237	211	1	references	reference	NOUN
dpc-4237	211	2	1	1	NUM
dpc-4237	211	3	.	.	PUNCT
dpc-4237	211	4	saini	saini	PROPN
dpc-4237	211	5	ss	ss	PROPN
dpc-4237	211	6	,	,	PUNCT
dpc-4237	211	7	kaplan	kaplan	PROPN
dpc-4237	211	8	ap	ap	PROPN
dpc-4237	211	9	.	.	PUNCT
dpc-4237	212	1	chronic	chronic	PROPN
dpc-4237	212	2	spontaneous	spontaneous	ADJ
dpc-4237	212	3	urticaria	urticaria	NOUN
dpc-4237	212	4	:	:	PUNCT
dpc-4237	212	5	the	the	DET
dpc-4237	212	6	devil	devil	NOUN
dpc-4237	212	7	’s	’s	PART
dpc-4237	212	8	itch	itch	NOUN
dpc-4237	212	9	:	:	PUNCT
dpc-4237	212	10	vol	vol	NOUN
dpc-4237	212	11	.	.	PROPN
dpc-4237	213	1	6	6	NUM
dpc-4237	213	2	.	.	X
dpc-4237	213	3	j	j	PROPN
dpc-4237	213	4	allergy	allergy	PROPN
dpc-4237	213	5	clin	clin	PROPN
dpc-4237	213	6	immunol	immunol	PROPN
dpc-4237	213	7	pract	pract	PROPN
dpc-4237	213	8	.	.	PUNCT
dpc-4237	214	1	2018;6(4	2018;6(4	NUM
dpc-4237	214	2	):	):	PUNCT
dpc-4237	214	3	1097–1106	1097–1106	NUM
dpc-4237	214	4	.	.	PUNCT
dpc-4237	215	1	doi	doi	NOUN
dpc-4237	215	2	:	:	PUNCT
dpc-4237	215	3	10.1016	10.1016	NUM
dpc-4237	215	4	/	/	SYM
dpc-4237	215	5	j.jaip.2018.04.013	j.jaip.2018.04.013	PROPN
dpc-4237	215	6	.	.	PUNCT
dpc-4237	215	7	  	  	SPACE
dpc-4237	216	1	2	2	NUM
dpc-4237	216	2	.	.	PUNCT
dpc-4237	217	1	gaig	gaig	PROPN
dpc-4237	217	2	p	p	X
dpc-4237	217	3	,	,	PUNCT
dpc-4237	217	4	olona	olona	PROPN
dpc-4237	217	5	m	m	PROPN
dpc-4237	217	6	,	,	PUNCT
dpc-4237	217	7	muñoz	muñoz	PROPN
dpc-4237	217	8	lejarazu	lejarazu	PROPN
dpc-4237	217	9	d	d	PROPN
dpc-4237	217	10	,	,	PUNCT
dpc-4237	217	11	et	et	PROPN
dpc-4237	217	12	al	al	PROPN
dpc-4237	217	13	.	.	PUNCT
dpc-4237	218	1	epidemiology	epidemiology	NOUN
dpc-4237	218	2	of	of	ADP
dpc-4237	218	3	urticaria	urticaria	NOUN
dpc-4237	218	4	in	in	ADP
dpc-4237	218	5	spain	spain	PROPN
dpc-4237	218	6	.	.	PUNCT
dpc-4237	219	1	j	j	PROPN
dpc-4237	219	2	investig	investig	PROPN
dpc-4237	219	3	allergol	allergol	PROPN
dpc-4237	219	4	clin	clin	PROPN
dpc-4237	219	5	immunol	immunol	NOUN
dpc-4237	219	6	.	.	PUNCT
dpc-4237	220	1	2004;14(3	2004;14(3	NUM
dpc-4237	220	2	):	):	PUNCT
dpc-4237	221	1	214–220	214–220	NUM
dpc-4237	221	2	.	.	PUNCT
dpc-4237	222	1	pmid	pmid	NOUN
dpc-4237	222	2	:	:	PUNCT
dpc-4237	222	3	15552715	15552715	NUM
dpc-4237	222	4	.	.	PUNCT
dpc-4237	223	1	3	3	X
dpc-4237	223	2	.	.	X
dpc-4237	223	3	bracken	bracken	PROPN
dpc-4237	223	4	sj	sj	PROPN
dpc-4237	223	5	,	,	PUNCT
dpc-4237	223	6	abraham	abraham	PROPN
dpc-4237	223	7	s	s	PROPN
dpc-4237	223	8	,	,	PUNCT
dpc-4237	223	9	macleod	macleod	PROPN
dpc-4237	223	10	as	as	ADP
dpc-4237	223	11	.	.	PUNCT
dpc-4237	223	12	autoimmune	autoimmune	PROPN
dpc-4237	223	13	theories	theory	NOUN
dpc-4237	223	14	of	of	ADP
dpc-4237	223	15	chronic	chronic	ADJ
dpc-4237	223	16	spontaneous	spontaneous	ADJ
dpc-4237	223	17	urticaria	urticaria	NOUN
dpc-4237	223	18	.	.	PUNCT
dpc-4237	224	1	front	front	ADJ
dpc-4237	224	2	immunol	immunol	NOUN
dpc-4237	224	3	.	.	PUNCT
dpc-4237	225	1	2019;10(3	2019;10(3	NUM
dpc-4237	225	2	):	):	PUNCT
dpc-4237	225	3	1–10	1–10	NOUN
dpc-4237	225	4	.	.	PUNCT
dpc-4237	226	1	doi	doi	NOUN
dpc-4237	226	2	:	:	PUNCT
dpc-4237	226	3	10.3389	10.3389	NUM
dpc-4237	226	4	/	/	SYM
dpc-4237	226	5	fimmu.2019.00627	fimmu.2019.00627	ADJ
dpc-4237	226	6	.	.	PUNCT
dpc-4237	227	1	4	4	X
dpc-4237	227	2	.	.	X
dpc-4237	227	3	hurtado	hurtado	NOUN
dpc-4237	227	4	-	-	PUNCT
dpc-4237	227	5	avilés	avilés	PROPN
dpc-4237	227	6	m	m	PROPN
dpc-4237	227	7	,	,	PUNCT
dpc-4237	227	8	martínez	martínez	PROPN
dpc-4237	227	9	-	-	PUNCT
dpc-4237	227	10	reculez	reculez	PROPN
dpc-4237	227	11	m	m	PROPN
dpc-4237	227	12	,	,	PUNCT
dpc-4237	227	13	vargas	vargas	NOUN
dpc-4237	227	14	-	-	PUNCT
dpc-4237	227	15	camaño	camaño	PROPN
dpc-4237	227	16	m	m	PROPN
dpc-4237	227	17	,	,	PUNCT
dpc-4237	227	18	castrejón	castrejón	ADJ
dpc-4237	227	19	-	-	PUNCT
dpc-4237	227	20	vázquez	vázquez	NOUN
dpc-4237	227	21	m.	m.	NOUN
dpc-4237	227	22	autoimmunity	autoimmunity	NOUN
dpc-4237	227	23	in	in	ADP
dpc-4237	227	24	chronic	chronic	ADJ
dpc-4237	227	25	urticaria	urticaria	NOUN
dpc-4237	227	26	.	.	PUNCT
dpc-4237	228	1	a	a	DET
dpc-4237	228	2	historical	historical	ADJ
dpc-4237	228	3	and	and	CCONJ
dpc-4237	228	4	current	current	ADJ
dpc-4237	228	5	perspective	perspective	NOUN
dpc-4237	228	6	.	.	PUNCT
dpc-4237	229	1	rev	rev	VERB
dpc-4237	229	2	alerg	alerg	PROPN
dpc-4237	229	3	mex	mex	PROPN
dpc-4237	229	4	.	.	PUNCT
dpc-4237	230	1	2022;69	2022;69	NUM
dpc-4237	230	2	:	:	PUNCT
dpc-4237	231	1	69	69	NUM
dpc-4237	231	2	-	-	SYM
dpc-4237	231	3	80	80	NUM
dpc-4237	231	4	.	.	PUNCT
dpc-4237	231	5	doi	doi	NOUN
dpc-4237	231	6	:	:	PUNCT
dpc-4237	231	7	10.29262	10.29262	NUM
dpc-4237	231	8	/	/	SYM
dpc-4237	231	9	ram.v69isupl1.1037	ram.v69isupl1.1037	PROPN
dpc-4237	231	10	.	.	PUNCT
dpc-4237	231	11	  	  	SPACE
dpc-4237	231	12	5	5	NUM
dpc-4237	231	13	.	.	PUNCT
dpc-4237	232	1	mu	mu	PROPN
dpc-4237	232	2	q	q	PROPN
dpc-4237	232	3	,	,	PUNCT
dpc-4237	232	4	kirby	kirby	PROPN
dpc-4237	232	5	j	j	PROPN
dpc-4237	232	6	,	,	PUNCT
dpc-4237	232	7	reilly	reilly	PROPN
dpc-4237	232	8	cm	cm	PROPN
dpc-4237	232	9	,	,	PUNCT
dpc-4237	232	10	luo	luo	PROPN
dpc-4237	232	11	xm	xm	PROPN
dpc-4237	232	12	.	.	PUNCT
dpc-4237	233	1	leaky	leaky	PROPN
dpc-4237	233	2	gut	gut	VERB
dpc-4237	233	3	as	as	ADP
dpc-4237	233	4	a	a	DET
dpc-4237	233	5	danger	danger	NOUN
dpc-4237	233	6	signal	signal	NOUN
dpc-4237	233	7	for	for	ADP
dpc-4237	233	8	autoimmune	autoimmune	ADJ
dpc-4237	233	9	diseases	disease	NOUN
dpc-4237	233	10	.	.	PUNCT
dpc-4237	234	1	front	front	ADJ
dpc-4237	234	2	immunol	immunol	NOUN
dpc-4237	234	3	.	.	PUNCT
dpc-4237	235	1	2017;8(5):1–10	2017;8(5):1–10	NUM
dpc-4237	235	2	.	.	PUNCT
dpc-4237	236	1	doi	doi	NOUN
dpc-4237	236	2	:	:	PUNCT
dpc-4237	236	3	10.3389	10.3389	NUM
dpc-4237	236	4	/	/	SYM
dpc-4237	236	5	fimmu.2017.00598	fimmu.2017.00598	NOUN
dpc-4237	236	6	.	.	NOUN
dpc-4237	237	1	6	6	NUM
dpc-4237	237	2	.	.	X
dpc-4237	237	3	vancamelbeke	vancamelbeke	PROPN
dpc-4237	237	4	m	m	PROPN
dpc-4237	237	5	,	,	PUNCT
dpc-4237	237	6	vermeire	vermeire	PROPN
dpc-4237	237	7	s.	s.	PROPN
dpc-4237	237	8	the	the	DET
dpc-4237	237	9	intestinal	intestinal	ADJ
dpc-4237	237	10	barrier	barrier	NOUN
dpc-4237	237	11	:	:	PUNCT
dpc-4237	237	12	a	a	DET
dpc-4237	237	13	fundamental	fundamental	ADJ
dpc-4237	237	14	role	role	NOUN
dpc-4237	237	15	in	in	ADP
dpc-4237	237	16	health	health	NOUN
dpc-4237	237	17	and	and	CCONJ
dpc-4237	237	18	disease	disease	NOUN
dpc-4237	237	19	.	.	PUNCT
dpc-4237	238	1	expert	expert	NOUN
dpc-4237	238	2	rev	rev	PROPN
dpc-4237	238	3	gastroenterol	gastroenterol	NOUN
dpc-4237	238	4	hepatol	hepatol	ADJ
dpc-4237	238	5	.	.	PUNCT
dpc-4237	239	1	2017;11(9):821–834	2017;11(9):821–834	X
dpc-4237	239	2	.	.	AUX
dpc-4237	239	3	 	 	SPACE
dpc-4237	239	4	doi:10.1080/17474124.2017.1343143	doi:10.1080/17474124.2017.1343143	PROPN
dpc-4237	239	5	.	.	PUNCT
dpc-4237	240	1	7	7	X
dpc-4237	240	2	.	.	X
dpc-4237	240	3	sekirov	sekirov	PROPN
dpc-4237	240	4	i	i	PRON
dpc-4237	240	5	,	,	PUNCT
dpc-4237	240	6	russell	russell	PROPN
dpc-4237	240	7	sl	sl	PROPN
dpc-4237	240	8	,	,	PUNCT
dpc-4237	240	9	caetano	caetano	PROPN
dpc-4237	240	10	m	m	PROPN
dpc-4237	240	11	antunes	antunes	PROPN
dpc-4237	240	12	l	l	PROPN
dpc-4237	240	13	,	,	PUNCT
dpc-4237	240	14	finlay	finlay	VERB
dpc-4237	240	15	bb	bb	NOUN
dpc-4237	240	16	.	.	PUNCT
dpc-4237	241	1	gut	gut	NOUN
dpc-4237	241	2	microbiota	microbiota	NOUN
dpc-4237	241	3	in	in	ADP
dpc-4237	241	4	health	health	NOUN
dpc-4237	241	5	and	and	CCONJ
dpc-4237	241	6	disease	disease	NOUN
dpc-4237	241	7	.	.	PUNCT
dpc-4237	242	1	physiol	physiol	PROPN
dpc-4237	242	2	rev	rev	PROPN
dpc-4237	242	3	.	.	PROPN
dpc-4237	243	1	2010;90(3):859–904	2010;90(3):859–904	X
dpc-4237	243	2	.	.	PUNCT
dpc-4237	243	3	doi	doi	NOUN
dpc-4237	243	4	:	:	PUNCT
dpc-4237	243	5	10.1152	10.1152	NUM
dpc-4237	243	6	/	/	SYM
dpc-4237	243	7	physrev.00045.2009	physrev.00045.2009	NOUN
dpc-4237	243	8	.	.	NOUN
dpc-4237	244	1	8	8	NUM
dpc-4237	244	2	.	.	PUNCT
dpc-4237	244	3	sturgeon	sturgeon	NOUN
dpc-4237	244	4	c	c	PROPN
dpc-4237	244	5	,	,	PUNCT
dpc-4237	244	6	fasano	fasano	PROPN
dpc-4237	244	7	a.	a.	PROPN
dpc-4237	244	8	zonulin	zonulin	PROPN
dpc-4237	244	9	,	,	PUNCT
dpc-4237	244	10	a	a	DET
dpc-4237	244	11	regulator	regulator	NOUN
dpc-4237	244	12	of	of	ADP
dpc-4237	244	13	epithelial	epithelial	ADJ
dpc-4237	244	14	and	and	CCONJ
dpc-4237	244	15	endothelial	endothelial	ADJ
dpc-4237	244	16	barrier	barrier	NOUN
dpc-4237	244	17	functions	function	NOUN
dpc-4237	244	18	,	,	PUNCT
dpc-4237	244	19	and	and	CCONJ
dpc-4237	244	20	its	its	PRON
dpc-4237	244	21	involvement	involvement	NOUN
dpc-4237	244	22	in	in	ADP
dpc-4237	244	23	chronic	chronic	ADJ
dpc-4237	244	24	inflammatory	inflammatory	ADJ
dpc-4237	244	25	diseases	disease	NOUN
dpc-4237	244	26	zonulin	zonulin	PROPN
dpc-4237	244	27	,	,	PUNCT
dpc-4237	244	28	a	a	DET
dpc-4237	244	29	regulator	regulator	NOUN
dpc-4237	244	30	of	of	ADP
dpc-4237	244	31	epithelial	epithelial	ADJ
dpc-4237	244	32	and	and	CCONJ
dpc-4237	244	33	endothelial	endothelial	ADJ
dpc-4237	244	34	barrier	barrier	NOUN
dpc-4237	244	35	functions	function	NOUN
dpc-4237	244	36	,	,	PUNCT
dpc-4237	244	37	and	and	CCONJ
dpc-4237	244	38	its	its	PRON
dpc-4237	244	39	involvement	involvement	NOUN
dpc-4237	244	40	in	in	ADP
dpc-4237	244	41	chronic	chronic	ADJ
dpc-4237	244	42	inflammatory	inflammatory	ADJ
dpc-4237	244	43	diseases	disease	NOUN
dpc-4237	244	44	.	.	PUNCT
dpc-4237	245	1	tissue	tissue	NOUN
dpc-4237	245	2	barriers	barrier	NOUN
dpc-4237	245	3	.	.	PUNCT
dpc-4237	246	1	2016	2016	NUM
dpc-4237	246	2	(	(	PUNCT
dpc-4237	246	3	1	1	NUM
dpc-4237	246	4	)	)	PUNCT
dpc-4237	246	5	;	;	PUNCT
dpc-4237	246	6	4(4	4(4	NUM
dpc-4237	246	7	)	)	PUNCT
dpc-4237	246	8	.	.	PUNCT
dpc-4237	247	1	doi	doi	NOUN
dpc-4237	247	2	:	:	PUNCT
dpc-4237	247	3	10.1080/21688370	10.1080/21688370	NUM
dpc-4237	247	4	.2016.1251384	.2016.1251384	NOUN
dpc-4237	247	5	.	.	PUNCT
dpc-4237	248	1	9	9	NUM
dpc-4237	248	2	.	.	X
dpc-4237	248	3	fasano	fasano	PROPN
dpc-4237	248	4	a.	a.	PROPN
dpc-4237	248	5	physiological	physiological	PROPN
dpc-4237	248	6	,	,	PUNCT
dpc-4237	248	7	pathological	pathological	ADJ
dpc-4237	248	8	,	,	PUNCT
dpc-4237	248	9	and	and	CCONJ
dpc-4237	248	10	therapeutic	therapeutic	ADJ
dpc-4237	248	11	implications	implication	NOUN
dpc-4237	248	12	of	of	ADP
dpc-4237	248	13	zonulin	zonulin	NOUN
dpc-4237	248	14	-	-	PUNCT
dpc-4237	248	15	mediated	mediate	VERB
dpc-4237	248	16	intestinal	intestinal	ADJ
dpc-4237	248	17	barrier	barrier	NOUN
dpc-4237	248	18	modulation	modulation	NOUN
dpc-4237	248	19	:	:	PUNCT
dpc-4237	248	20	living	live	VERB
dpc-4237	248	21	life	life	NOUN
dpc-4237	248	22	on	on	ADP
dpc-4237	248	23	the	the	DET
dpc-4237	248	24	edge	edge	NOUN
dpc-4237	248	25	of	of	ADP
dpc-4237	248	26	the	the	DET
dpc-4237	248	27	wall	wall	NOUN
dpc-4237	248	28	.	.	PUNCT
dpc-4237	248	29	am	be	AUX
dpc-4237	248	30	j	j	PROPN
dpc-4237	248	31	pathol	pathol	NOUN
dpc-4237	248	32	.	.	PUNCT
dpc-4237	249	1	2008;173(5	2008;173(5	NUM
dpc-4237	249	2	):	):	PUNCT
dpc-4237	249	3	1243–1252	1243–1252	NUM
dpc-4237	249	4	.	.	PUNCT
dpc-4237	250	1	doi	doi	NOUN
dpc-4237	250	2	:	:	PUNCT
dpc-4237	250	3	10.2353	10.2353	NUM
dpc-4237	250	4	/	/	SYM
dpc-4237	250	5	ajpath.2008.080192	ajpath.2008.080192	PROPN
dpc-4237	250	6	.	.	PUNCT
dpc-4237	251	1	10	10	NUM
dpc-4237	251	2	.	.	PUNCT
dpc-4237	251	3	fasano	fasano	PROPN
dpc-4237	251	4	a.	a.	PROPN
dpc-4237	251	5	intestinal	intestinal	PROPN
dpc-4237	251	6	permeability	permeability	NOUN
dpc-4237	251	7	and	and	CCONJ
dpc-4237	251	8	its	its	PRON
dpc-4237	251	9	regulation	regulation	NOUN
dpc-4237	251	10	by	by	ADP
dpc-4237	251	11	zonulin	zonulin	NOUN
dpc-4237	251	12	:	:	PUNCT
dpc-4237	251	13	diagnostic	diagnostic	ADJ
dpc-4237	251	14	and	and	CCONJ
dpc-4237	251	15	therapeutic	therapeutic	ADJ
dpc-4237	251	16	implications	implication	NOUN
dpc-4237	251	17	.	.	PUNCT
dpc-4237	252	1	clin	clin	PROPN
dpc-4237	252	2	gastroenterol	gastroenterol	PROPN
dpc-4237	252	3	hepatol	hepatol	ADJ
dpc-4237	252	4	.	.	PUNCT
dpc-4237	253	1	2012	2012	NUM
dpc-4237	253	2	oct	oct	NOUN
dpc-4237	253	3	1;10(10):1096–1100	1;10(10):1096–1100	NUM
dpc-4237	253	4	.	.	PUNCT
dpc-4237	254	1	doi	doi	NOUN
dpc-4237	254	2	:	:	PUNCT
dpc-4237	254	3	10.1016	10.1016	NUM
dpc-4237	254	4	/	/	SYM
dpc-4237	254	5	j.cgh.2012	j.cgh.2012	PROPN
dpc-4237	254	6	.08.012	.08.012	PROPN
dpc-4237	254	7	.	.	PUNCT