id sid tid token lemma pos dpc-459 1 1 104 104 NUM dpc-459 1 2 research research NOUN dpc-459 1 3 | | ADV dpc-459 1 4 dermatol dermatol ADJ dpc-459 1 5 pract pract NOUN dpc-459 1 6 concept concept NOUN dpc-459 1 7 2018;8(2):7 2018;8(2):7 NUM dpc-459 1 8 dermatology dermatology NOUN dpc-459 1 9 practical practical ADJ dpc-459 1 10 & & CCONJ dpc-459 1 11 conceptual conceptual ADJ dpc-459 1 12 www.derm101.com www.derm101.com X dpc-459 1 13 morphologic morphologic ADJ dpc-459 1 14 characteristics characteristic NOUN dpc-459 1 15 of of ADP dpc-459 1 16 nevi nevi NOUN dpc-459 1 17 associated associate VERB dpc-459 1 18 with with ADP dpc-459 1 19 melanoma melanoma NOUN dpc-459 1 20 : : PUNCT dpc-459 1 21 a a DET dpc-459 1 22 clinical clinical ADJ dpc-459 1 23 , , PUNCT dpc-459 1 24 dermatoscopic dermatoscopic ADJ dpc-459 1 25 and and CCONJ dpc-459 1 26 histopathologic histopathologic ADJ dpc-459 1 27 analysis analysis NOUN dpc-459 1 28 temeida temeida PROPN dpc-459 1 29 alendar1 alendar1 PROPN dpc-459 1 30 , , PUNCT dpc-459 1 31 harald harald PROPN dpc-459 1 32 kittler1 kittler1 PROPN dpc-459 1 33 1 1 NUM dpc-459 1 34     SPACE dpc-459 1 35 department department NOUN dpc-459 1 36 of of ADP dpc-459 1 37 dermatology dermatology NOUN dpc-459 1 38 , , PUNCT dpc-459 1 39 medical medical ADJ dpc-459 1 40 university university NOUN dpc-459 1 41 vienna vienna PROPN dpc-459 1 42 , , PUNCT dpc-459 1 43 vienna vienna PROPN dpc-459 1 44 , , PUNCT dpc-459 1 45 austria austria PROPN dpc-459 1 46 key key ADJ dpc-459 1 47 words word NOUN dpc-459 1 48 : : PUNCT dpc-459 1 49 nevus nevus ADJ dpc-459 1 50 , , PUNCT dpc-459 1 51 melanoma melanoma NOUN dpc-459 1 52 , , PUNCT dpc-459 1 53 dermatopathology dermatopathology NOUN dpc-459 1 54 , , PUNCT dpc-459 1 55 dermatoscopy dermatoscopy VERB dpc-459 1 56 citation citation NOUN dpc-459 1 57 : : PUNCT dpc-459 1 58 alendar alendar PROPN dpc-459 1 59 t t PROPN dpc-459 1 60 , , PUNCT dpc-459 1 61 kittler kittler NOUN dpc-459 1 62 h. h. PROPN dpc-459 1 63 morphologic morphologic ADJ dpc-459 1 64 characteristics characteristic NOUN dpc-459 1 65 of of ADP dpc-459 1 66 nevi nevi NOUN dpc-459 1 67 associated associate VERB dpc-459 1 68 with with ADP dpc-459 1 69 melanoma melanoma NOUN dpc-459 1 70 : : PUNCT dpc-459 1 71 a a DET dpc-459 1 72 clinical clinical ADJ dpc-459 1 73 , , PUNCT dpc-459 1 74 dermatoscopic dermatoscopic ADJ dpc-459 1 75 and and CCONJ dpc-459 1 76 histopathologic histopathologic ADJ dpc-459 1 77 analysis analysis NOUN dpc-459 1 78 . . PUNCT dpc-459 2 1 dermatol dermatol NOUN dpc-459 2 2 pract pract PROPN dpc-459 2 3 concept concept NOUN dpc-459 2 4 . . PUNCT dpc-459 3 1 2018;8(2):104 2018;8(2):104 X dpc-459 3 2 - - SYM dpc-459 3 3 108 108 NUM dpc-459 3 4 . . PUNCT dpc-459 4 1 doi doi NOUN dpc-459 4 2 : : PUNCT dpc-459 4 3 https://doi.org/10.5826/dpc.0802a07 https://doi.org/10.5826/dpc.0802a07 ADJ dpc-459 4 4 received receive VERB dpc-459 4 5 : : PUNCT dpc-459 4 6 january january PROPN dpc-459 4 7     SPACE dpc-459 4 8 8 8 NUM dpc-459 4 9 , , PUNCT dpc-459 4 10 2018 2018 NUM dpc-459 4 11 ; ; PUNCT dpc-459 4 12 accepted accept VERB dpc-459 4 13 : : PUNCT dpc-459 4 14 february february PROPN dpc-459 4 15     SPACE dpc-459 4 16 1 1 NUM dpc-459 4 17 , , PUNCT dpc-459 4 18 2018 2018 NUM dpc-459 4 19 ; ; PUNCT dpc-459 4 20 published publish VERB dpc-459 4 21 : : PUNCT dpc-459 4 22 april april PROPN dpc-459 4 23     SPACE dpc-459 4 24 30 30 NUM dpc-459 4 25 , , PUNCT dpc-459 4 26 2018 2018 NUM dpc-459 4 27 copyright copyright NOUN dpc-459 4 28 : : PUNCT dpc-459 4 29 © © PROPN dpc-459 4 30 2018 2018 NUM dpc-459 4 31     SPACE dpc-459 4 32 alendar alendar PROPN dpc-459 4 33 et et PROPN dpc-459 4 34     SPACE dpc-459 4 35 al al PROPN dpc-459 4 36 . . PUNCT dpc-459 5 1 this this PRON dpc-459 5 2 is be AUX dpc-459 5 3 an an DET dpc-459 5 4 open open ADJ dpc-459 5 5 - - PUNCT dpc-459 5 6 access access NOUN dpc-459 5 7 article article NOUN dpc-459 5 8 distributed distribute VERB dpc-459 5 9 under under ADP dpc-459 5 10 the the DET dpc-459 5 11 terms term NOUN dpc-459 5 12 of of ADP dpc-459 5 13 the the DET dpc-459 5 14 creative creative ADJ dpc-459 5 15 commons common NOUN dpc-459 5 16 attribution attribution NOUN dpc-459 5 17 license license NOUN dpc-459 5 18 , , PUNCT dpc-459 5 19 which which PRON dpc-459 5 20 permits permit VERB dpc-459 5 21 unrestricted unrestricted ADJ dpc-459 5 22 use use NOUN dpc-459 5 23 , , PUNCT dpc-459 5 24 distribution distribution NOUN dpc-459 5 25 , , PUNCT dpc-459 5 26 and and CCONJ dpc-459 5 27 reproduction reproduction NOUN dpc-459 5 28 in in ADP dpc-459 5 29 any any DET dpc-459 5 30 medium medium NOUN dpc-459 5 31 , , PUNCT dpc-459 5 32 provided provide VERB dpc-459 5 33 the the DET dpc-459 5 34 original original ADJ dpc-459 5 35 author author NOUN dpc-459 5 36 and and CCONJ dpc-459 5 37 source source NOUN dpc-459 5 38 are be AUX dpc-459 5 39     SPACE dpc-459 5 40 credited credit VERB dpc-459 5 41 . . PUNCT dpc-459 6 1 funding funding NOUN dpc-459 6 2 : : PUNCT dpc-459 6 3 none none NOUN dpc-459 6 4 . . PUNCT dpc-459 7 1 competing compete VERB dpc-459 7 2 interests interest NOUN dpc-459 7 3 : : PUNCT dpc-459 7 4 the the DET dpc-459 7 5 authors author NOUN dpc-459 7 6 have have VERB dpc-459 7 7 no no DET dpc-459 7 8 conflicts conflict NOUN dpc-459 7 9 of of ADP dpc-459 7 10 interest interest NOUN dpc-459 7 11 to to PART dpc-459 7 12     SPACE dpc-459 7 13 disclose disclose VERB dpc-459 7 14 . . PUNCT dpc-459 8 1 all all DET dpc-459 8 2 authors author NOUN dpc-459 8 3 have have AUX dpc-459 8 4 contributed contribute VERB dpc-459 8 5 significantly significantly ADV dpc-459 8 6 to to ADP dpc-459 8 7 this this DET dpc-459 8 8 publication publication NOUN dpc-459 8 9 . . PUNCT dpc-459 9 1 corresponding correspond VERB dpc-459 9 2 author author NOUN dpc-459 9 3 : : PUNCT dpc-459 9 4 harald harald PROPN dpc-459 9 5 kittler kittler PROPN dpc-459 9 6 , , PUNCT dpc-459 9 7 md md PROPN dpc-459 9 8 , , PUNCT dpc-459 9 9 department department PROPN dpc-459 9 10 of of ADP dpc-459 9 11 dermatology dermatology NOUN dpc-459 9 12 , , PUNCT dpc-459 9 13 medical medical ADJ dpc-459 9 14 university university NOUN dpc-459 9 15 vienna vienna PROPN dpc-459 9 16 , , PUNCT dpc-459 9 17 waehringer waehringer PROPN dpc-459 9 18 gürtel gürtel PROPN dpc-459 9 19     SPACE dpc-459 9 20 18 18 NUM dpc-459 9 21 - - SYM dpc-459 9 22 20 20 NUM dpc-459 9 23 , , PUNCT dpc-459 9 24 1090 1090 NUM dpc-459 9 25 , , PUNCT dpc-459 9 26 vienna vienna PROPN dpc-459 9 27 , , PUNCT dpc-459 9 28 austria austria PROPN dpc-459 9 29 . . PUNCT dpc-459 10 1 tel tel ADP dpc-459 10 2 : : PUNCT dpc-459 10 3 + + NOUN dpc-459 10 4 +44.1.40400.77110 +44.1.40400.77110 NOUN dpc-459 10 5 . . PUNCT dpc-459 11 1 email email NOUN dpc-459 11 2 : : PUNCT dpc-459 11 3 harald.kittler@meduniwien.ac.at harald.kittler@meduniwien.ac.at NUM dpc-459 11 4 background background NOUN dpc-459 11 5 : : PUNCT dpc-459 11 6 the the DET dpc-459 11 7 aim aim NOUN dpc-459 11 8 of of ADP dpc-459 11 9 this this DET dpc-459 11 10 retrospective retrospective ADJ dpc-459 11 11 study study NOUN dpc-459 11 12 was be AUX dpc-459 11 13 to to PART dpc-459 11 14 determine determine VERB dpc-459 11 15 the the DET dpc-459 11 16 frequency frequency NOUN dpc-459 11 17 of of ADP dpc-459 11 18 nevus nevus NOUN dpc-459 11 19 - - PUNCT dpc-459 11 20 associated associate VERB dpc-459 11 21 melanomas melanomas NOUN dpc-459 11 22 and and CCONJ dpc-459 11 23 to to PART dpc-459 11 24 better well ADV dpc-459 11 25 characterize characterize VERB dpc-459 11 26 the the DET dpc-459 11 27 preexisting preexist VERB dpc-459 11 28 nevus nevus NOUN dpc-459 11 29 from from ADP dpc-459 11 30 a a DET dpc-459 11 31 histopathologic histopathologic NOUN dpc-459 11 32 , , PUNCT dpc-459 11 33 clinical clinical ADJ dpc-459 11 34 and and CCONJ dpc-459 11 35 dermatoscopic dermatoscopic ADJ dpc-459 11 36 point point NOUN dpc-459 11 37 of of ADP dpc-459 11 38     SPACE dpc-459 11 39 view view NOUN dpc-459 11 40 . . PUNCT dpc-459 12 1 methods method NOUN dpc-459 12 2 : : PUNCT dpc-459 12 3 we we PRON dpc-459 12 4 reviewed review VERB dpc-459 12 5 the the DET dpc-459 12 6 histopathologic histopathologic NOUN dpc-459 12 7 slides slide NOUN dpc-459 12 8 of of ADP dpc-459 12 9 a a DET dpc-459 12 10 consecutive consecutive ADJ dpc-459 12 11 series series NOUN dpc-459 12 12 of of ADP dpc-459 12 13     SPACE dpc-459 12 14 357 357 NUM dpc-459 12 15     SPACE dpc-459 12 16 melanomas melanomas NOUN dpc-459 12 17 and and CCONJ dpc-459 12 18 corresponding corresponding ADJ dpc-459 12 19 clinical clinical ADJ dpc-459 12 20 and and CCONJ dpc-459 12 21 dermatoscopic dermatoscopic ADJ dpc-459 12 22 images image NOUN dpc-459 12 23 , , PUNCT dpc-459 12 24 if if SCONJ dpc-459 12 25 available available ADJ dpc-459 12 26 . . PUNCT dpc-459 13 1 results result NOUN dpc-459 13 2 : : PUNCT dpc-459 13 3 we we PRON dpc-459 13 4 found find VERB dpc-459 13 5 that that SCONJ dpc-459 13 6     SPACE dpc-459 13 7 31 31 NUM dpc-459 13 8 ( ( PUNCT dpc-459 13 9 8.7 8.7 NUM dpc-459 13 10 % % NOUN dpc-459 13 11 ) ) PUNCT dpc-459 13 12 melanomas melanomas PROPN dpc-459 13 13 were be AUX dpc-459 13 14 associated associate VERB dpc-459 13 15 with with ADP dpc-459 13 16 a a DET dpc-459 13 17 preexisting preexist VERB dpc-459 13 18 nevus nevus NOUN dpc-459 13 19 , , PUNCT dpc-459 13 20 284 284 NUM dpc-459 13 21 ( ( PUNCT dpc-459 13 22 79.5 79.5 NUM dpc-459 13 23 % % NOUN dpc-459 13 24 ) ) PUNCT dpc-459 13 25 melanomas melanomas PROPN dpc-459 13 26 developed develop VERB dpc-459 13 27 de de NOUN dpc-459 13 28 novo novo NOUN dpc-459 13 29 , , PUNCT dpc-459 13 30 and and CCONJ dpc-459 13 31 in in ADP dpc-459 13 32     SPACE dpc-459 13 33 42 42 NUM dpc-459 13 34 ( ( PUNCT dpc-459 13 35 11.8 11.8 NUM dpc-459 13 36 % % NOUN dpc-459 13 37 ) ) PUNCT dpc-459 13 38 a a DET dpc-459 13 39 preexisting preexist VERB dpc-459 13 40 nevus nevus NOUN dpc-459 13 41 could could AUX dpc-459 13 42 not not PART dpc-459 13 43 be be AUX dpc-459 13 44 excluded exclude VERB dpc-459 13 45 , , PUNCT dpc-459 13 46 although although SCONJ dpc-459 13 47 the the DET dpc-459 13 48 alternative alternative ADJ dpc-459 13 49 explanation explanation NOUN dpc-459 13 50 that that SCONJ dpc-459 13 51 the the DET dpc-459 13 52 entire entire ADJ dpc-459 13 53 lesion lesion NOUN dpc-459 13 54 represented represent VERB dpc-459 13 55 a a DET dpc-459 13 56 melanoma melanoma NOUN dpc-459 13 57 was be AUX dpc-459 13 58 also also ADV dpc-459 13 59 possible possible ADJ dpc-459 13 60 . . PUNCT dpc-459 14 1 the the DET dpc-459 14 2 preexisting preexist VERB dpc-459 14 3 nevus nevus NOUN dpc-459 14 4 was be AUX dpc-459 14 5 a a DET dpc-459 14 6 “ " PUNCT dpc-459 14 7 superficial superficial ADJ dpc-459 14 8 ” " PUNCT dpc-459 14 9 or or CCONJ dpc-459 14 10 “ " PUNCT dpc-459 14 11 superficial superficial ADJ dpc-459 14 12 and and CCONJ dpc-459 14 13 deep deep ADJ dpc-459 14 14 ” " PUNCT dpc-459 14 15 congenital congenital ADJ dpc-459 14 16 nevus nevus NOUN dpc-459 14 17 in in ADP dpc-459 14 18     SPACE dpc-459 14 19 27 27 NUM dpc-459 14 20     SPACE dpc-459 14 21 cases case NOUN dpc-459 14 22 ( ( PUNCT dpc-459 14 23 87 87 NUM dpc-459 14 24 % % NOUN dpc-459 14 25 ) ) PUNCT dpc-459 14 26 and and CCONJ dpc-459 14 27 a a DET dpc-459 14 28 clark clark NOUN dpc-459 14 29 nevus nevus NOUN dpc-459 14 30 in in ADP dpc-459 14 31     SPACE dpc-459 14 32 4 4 NUM dpc-459 14 33     SPACE dpc-459 14 34 cases case NOUN dpc-459 14 35 ( ( PUNCT dpc-459 14 36 13 13 NUM dpc-459 14 37 % % NOUN dpc-459 14 38 ) ) PUNCT dpc-459 14 39 . . PUNCT dpc-459 15 1 clinical clinical ADJ dpc-459 15 2 or or CCONJ dpc-459 15 3 dermatoscopic dermatoscopic ADJ dpc-459 15 4 images image NOUN dpc-459 15 5 were be AUX dpc-459 15 6 available available ADJ dpc-459 15 7 in in ADP dpc-459 15 8     SPACE dpc-459 15 9 149 149 NUM dpc-459 15 10 ( ( PUNCT dpc-459 15 11 41.7 41.7 NUM dpc-459 15 12 % % NOUN dpc-459 15 13 ) ) PUNCT dpc-459 15 14 cases case NOUN dpc-459 15 15 . . PUNCT dpc-459 16 1 the the DET dpc-459 16 2 preexisting preexist VERB dpc-459 16 3 nevus nevus NOUN dpc-459 16 4 , , PUNCT dpc-459 16 5 if if SCONJ dpc-459 16 6 visible visible ADJ dpc-459 16 7 , , PUNCT dpc-459 16 8 looked look VERB dpc-459 16 9 inconspicuous inconspicuous ADJ dpc-459 16 10 clinically clinically ADV dpc-459 16 11 or or CCONJ dpc-459 16 12 dermatoscopically dermatoscopically ADV dpc-459 16 13 . . PUNCT dpc-459 17 1 the the DET dpc-459 17 2 median median ADJ dpc-459 17 3 invasion invasion NOUN dpc-459 17 4 thickness thickness NOUN dpc-459 17 5 of of ADP dpc-459 17 6 nevus nevus ADJ dpc-459 17 7 - - PUNCT dpc-459 17 8 associated associate VERB dpc-459 17 9 melanoma melanoma NOUN dpc-459 17 10 was be AUX dpc-459 17 11 not not PART dpc-459 17 12 significantly significantly ADV dpc-459 17 13 different different ADJ dpc-459 17 14 from from ADP dpc-459 17 15 “ " PUNCT dpc-459 17 16 de de X dpc-459 17 17 novo novo NOUN dpc-459 17 18 ” " PUNCT dpc-459 17 19 melanomas melanomas NOUN dpc-459 17 20 but but CCONJ dpc-459 17 21 the the DET dpc-459 17 22 frequency frequency NOUN dpc-459 17 23 of of ADP dpc-459 17 24 in in ADP dpc-459 17 25 situ situ ADJ dpc-459 17 26 melanomas melanomas NOUN dpc-459 17 27 was be AUX dpc-459 17 28 higher high ADJ dpc-459 17 29 in in ADP dpc-459 17 30 the the DET dpc-459 17 31 “ " PUNCT dpc-459 17 32 de de X dpc-459 17 33 novo novo NOUN dpc-459 17 34 “ " PUNCT dpc-459 17 35 group group NOUN dpc-459 17 36 ( ( PUNCT dpc-459 17 37 40.1 40.1 NUM dpc-459 17 38 % % NOUN dpc-459 17 39 versus versus ADP dpc-459 17 40     SPACE dpc-459 17 41 16.1 16.1 NUM dpc-459 17 42 % % NOUN dpc-459 17 43 ) ) PUNCT dpc-459 17 44 . . PUNCT dpc-459 18 1 patients patient NOUN dpc-459 18 2 with with ADP dpc-459 18 3 melanoma melanoma NOUN dpc-459 18 4 in in ADP dpc-459 18 5 association association NOUN dpc-459 18 6 with with ADP dpc-459 18 7 a a DET dpc-459 18 8 nevus nevus NOUN dpc-459 18 9 were be AUX dpc-459 18 10 significantly significantly ADV dpc-459 18 11 younger young ADJ dpc-459 18 12 ( ( PUNCT dpc-459 18 13 mean mean PROPN dpc-459 18 14 age=55 age=55 PROPN dpc-459 18 15     SPACE dpc-459 18 16 years year NOUN dpc-459 18 17 , , PUNCT dpc-459 18 18 sd sd ADP dpc-459 18 19 : : PUNCT dpc-459 18 20 16 16 NUM dpc-459 18 21     SPACE dpc-459 18 22 years year NOUN dpc-459 18 23 ) ) PUNCT dpc-459 18 24 than than ADP dpc-459 18 25 patients patient NOUN dpc-459 18 26 with with ADP dpc-459 18 27 “ " PUNCT dpc-459 18 28 de de X dpc-459 18 29 novo novo NOUN dpc-459 18 30 ” " PUNCT dpc-459 18 31 melanomas melanomas NOUN dpc-459 18 32 ( ( PUNCT dpc-459 18 33 mean mean NOUN dpc-459 18 34 age=68 age=68 CCONJ dpc-459 18 35     SPACE dpc-459 18 36 years year NOUN dpc-459 18 37 sd sd NOUN dpc-459 18 38 : : PUNCT dpc-459 18 39 15 15 NUM dpc-459 18 40     SPACE dpc-459 18 41 years year NOUN dpc-459 18 42 , , PUNCT dpc-459 18 43 p<0.001 p<0.001 PROPN dpc-459 18 44 ) ) PUNCT dpc-459 18 45 . . PUNCT dpc-459 19 1 when when SCONJ dpc-459 19 2 controlled control VERB dpc-459 19 3 for for ADP dpc-459 19 4 age age NOUN dpc-459 19 5 and and CCONJ dpc-459 19 6 invasion invasion NOUN dpc-459 19 7 thickness thickness NOUN dpc-459 19 8 overall overall ADV dpc-459 19 9 , , PUNCT dpc-459 19 10 survival survival NOUN dpc-459 19 11 did do AUX dpc-459 19 12 not not PART dpc-459 19 13 differ differ VERB dpc-459 19 14 significantly significantly ADV dpc-459 19 15 between between ADP dpc-459 19 16 patients patient NOUN dpc-459 19 17 with with ADP dpc-459 19 18 nevus nevus NOUN dpc-459 19 19 - - PUNCT dpc-459 19 20 associated associate VERB dpc-459 19 21 melanomas melanoma NOUN dpc-459 19 22 and and CCONJ dpc-459 19 23 patients patient NOUN dpc-459 19 24 with with ADP dpc-459 19 25 de de X dpc-459 19 26 novo novo NOUN dpc-459 19 27 melanomas melanomas PROPN dpc-459 19 28 . . PUNCT dpc-459 20 1 conclusions conclusion NOUN dpc-459 20 2 : : PUNCT dpc-459 20 3 from from ADP dpc-459 20 4 a a DET dpc-459 20 5 histomorphologic histomorphologic ADJ dpc-459 20 6 point point NOUN dpc-459 20 7 of of ADP dpc-459 20 8 view view NOUN dpc-459 20 9 , , PUNCT dpc-459 20 10 the the DET dpc-459 20 11 majority majority NOUN dpc-459 20 12 of of ADP dpc-459 20 13 melanomas melanomas PROPN dpc-459 20 14 arise arise PROPN dpc-459 20 15 de de X dpc-459 20 16 novo novo PROPN dpc-459 20 17 . . PUNCT dpc-459 21 1 if if SCONJ dpc-459 21 2 melanomas melanoma NOUN dpc-459 21 3 develop develop VERB dpc-459 21 4 in in ADP dpc-459 21 5 a a DET dpc-459 21 6 preexisting preexist VERB dpc-459 21 7 nevus nevus NOUN dpc-459 21 8 , , PUNCT dpc-459 21 9 they they PRON dpc-459 21 10 usually usually ADV dpc-459 21 11 occur occur VERB dpc-459 21 12 in in ADP dpc-459 21 13 association association NOUN dpc-459 21 14 with with ADP dpc-459 21 15 a a DET dpc-459 21 16 “ " PUNCT dpc-459 21 17 superficial superficial ADJ dpc-459 21 18 ” " PUNCT dpc-459 21 19 or or CCONJ dpc-459 21 20 “ " PUNCT dpc-459 21 21 superficial superficial ADJ dpc-459 21 22 and and CCONJ dpc-459 21 23 deep deep ADJ dpc-459 21 24 ” " PUNCT dpc-459 21 25 congenital congenital ADJ dpc-459 21 26 nevus nevus NOUN dpc-459 21 27 . . PUNCT dpc-459 22 1 abstract abstract ADJ dpc-459 22 2 research research NOUN dpc-459 22 3 | | ADV dpc-459 22 4 dermatol dermatol ADJ dpc-459 22 5 pract pract NOUN dpc-459 22 6 concept concept NOUN dpc-459 22 7 2018;8(2):7 2018;8(2):7 NOUN dpc-459 22 8 105 105 NUM dpc-459 22 9 toscopic toscopic NOUN dpc-459 22 10 images image NOUN dpc-459 22 11 on on ADP dpc-459 22 12 a a DET dpc-459 22 13 computer computer NOUN dpc-459 22 14 screen screen NOUN dpc-459 22 15 without without ADP dpc-459 22 16 knowledge knowledge NOUN dpc-459 22 17 of of ADP dpc-459 22 18 the the DET dpc-459 22 19 histopathologic histopathologic ADJ dpc-459 22 20 diagnosis diagnosis NOUN dpc-459 22 21 . . PUNCT dpc-459 23 1 statistical statistical ADJ dpc-459 23 2 analysis analysis NOUN dpc-459 23 3 continuous continuous ADJ dpc-459 23 4 data datum NOUN dpc-459 23 5 are be AUX dpc-459 23 6 given give VERB dpc-459 23 7 as as ADV dpc-459 23 8 mean mean ADJ dpc-459 23 9 and and CCONJ dpc-459 23 10 standard standard ADJ dpc-459 23 11 deviations deviation NOUN dpc-459 23 12 ( ( PUNCT dpc-459 23 13 sd sd NOUN dpc-459 23 14 ) ) PUNCT dpc-459 23 15 or or CCONJ dpc-459 23 16 as as ADP dpc-459 23 17 median median ADJ dpc-459 23 18 and and CCONJ dpc-459 23 19 range range NOUN dpc-459 23 20 , , PUNCT dpc-459 23 21 as as ADP dpc-459 23 22 appropriate appropriate ADJ dpc-459 23 23 . . PUNCT dpc-459 24 1 t t NOUN dpc-459 24 2 - - PUNCT dpc-459 24 3 tests test NOUN dpc-459 24 4 or or CCONJ dpc-459 24 5 mann mann PROPN dpc-459 24 6 - - PUNCT dpc-459 24 7 whitney whitney PROPN dpc-459 24 8 u u NOUN dpc-459 24 9 tests test NOUN dpc-459 24 10 were be AUX dpc-459 24 11 used use VERB dpc-459 24 12 to to PART dpc-459 24 13 compare compare VERB dpc-459 24 14 groups group NOUN dpc-459 24 15 and and CCONJ dpc-459 24 16 the the DET dpc-459 24 17 chi chi ADJ dpc-459 24 18 - - PUNCT dpc-459 24 19 square square ADJ dpc-459 24 20 test test NOUN dpc-459 24 21 for for ADP dpc-459 24 22 the the DET dpc-459 24 23 comparison comparison NOUN dpc-459 24 24 of of ADP dpc-459 24 25 proportions proportion NOUN dpc-459 24 26 . . PUNCT dpc-459 25 1 the the DET dpc-459 25 2 kaplan kaplan PROPN dpc-459 25 3 - - PUNCT dpc-459 25 4 meier meier PROPN dpc-459 25 5 method method NOUN dpc-459 25 6 and and CCONJ dpc-459 25 7 a a DET dpc-459 25 8 cox cox PROPN dpc-459 25 9 proportional proportional NOUN dpc-459 25 10 hazards hazard NOUN dpc-459 25 11 analysis analysis NOUN dpc-459 25 12 were be AUX dpc-459 25 13 used use VERB dpc-459 25 14 to to PART dpc-459 25 15 analyze analyze VERB dpc-459 25 16 differences difference NOUN dpc-459 25 17 in in ADP dpc-459 25 18 overall overall ADJ dpc-459 25 19 survival survival NOUN dpc-459 25 20 . . PUNCT dpc-459 26 1 all all PRON dpc-459 26 2 given give VERB dpc-459 26 3 p p NOUN dpc-459 26 4 - - PUNCT dpc-459 26 5 values value NOUN dpc-459 26 6 are be AUX dpc-459 26 7 two two NUM dpc-459 26 8 - - PUNCT dpc-459 26 9 tailed tail VERB dpc-459 26 10 . . PUNCT dpc-459 27 1 a a DET dpc-459 27 2 p p NOUN dpc-459 27 3 - - PUNCT dpc-459 27 4 value value NOUN dpc-459 27 5 < < NOUN dpc-459 27 6 .05 .05 NUM dpc-459 27 7     SPACE dpc-459 27 8 was be AUX dpc-459 27 9 considered consider VERB dpc-459 27 10 statistically statistically ADV dpc-459 27 11 significant significant ADJ dpc-459 27 12 . . PUNCT dpc-459 28 1 results result NOUN dpc-459 28 2 general general ADJ dpc-459 28 3 data datum NOUN dpc-459 28 4 we we PRON dpc-459 28 5 included include VERB dpc-459 28 6     SPACE dpc-459 28 7 357 357 NUM dpc-459 28 8     SPACE dpc-459 28 9 melanomas melanomas NOUN dpc-459 28 10 of of ADP dpc-459 28 11     SPACE dpc-459 28 12 194 194 NUM dpc-459 28 13     SPACE dpc-459 28 14 males male NOUN dpc-459 28 15 ( ( PUNCT dpc-459 28 16 54.3 54.3 NUM dpc-459 28 17 % % NOUN dpc-459 28 18 ) ) PUNCT dpc-459 28 19 and and CCONJ dpc-459 28 20     SPACE dpc-459 28 21 163 163 NUM dpc-459 28 22     SPACE dpc-459 28 23 females female NOUN dpc-459 28 24 ( ( PUNCT dpc-459 28 25 45.7 45.7 NUM dpc-459 28 26 % % NOUN dpc-459 28 27 ) ) PUNCT dpc-459 28 28 . . PUNCT dpc-459 29 1 the the DET dpc-459 29 2 mean mean ADJ dpc-459 29 3 age age NOUN dpc-459 29 4 was be AUX dpc-459 29 5     SPACE dpc-459 29 6 66.4 66.4 NUM dpc-459 29 7     SPACE dpc-459 29 8 years year NOUN dpc-459 29 9 ( ( PUNCT dpc-459 29 10 sd sd NOUN dpc-459 29 11 : : PUNCT dpc-459 29 12 15.4 15.4 NUM dpc-459 29 13 ) ) PUNCT dpc-459 29 14 . . PUNCT dpc-459 30 1 the the DET dpc-459 30 2 majority majority NOUN dpc-459 30 3 of of ADP dpc-459 30 4 melanomas melanoma NOUN dpc-459 30 5 were be AUX dpc-459 30 6 located locate VERB dpc-459 30 7 on on ADP dpc-459 30 8 the the DET dpc-459 30 9 trunk trunk NOUN dpc-459 30 10 ( ( PUNCT dpc-459 30 11 n=118 n=118 NUM dpc-459 30 12 , , PUNCT dpc-459 30 13 33 33 NUM dpc-459 30 14 % % NOUN dpc-459 30 15 ) ) PUNCT dpc-459 30 16 , , PUNCT dpc-459 30 17 137 137 NUM dpc-459 30 18 ( ( PUNCT dpc-459 30 19 38.4 38.4 NUM dpc-459 30 20 % % NOUN dpc-459 30 21 ) ) PUNCT dpc-459 30 22 melanomas melanoma NOUN dpc-459 30 23 were be AUX dpc-459 30 24 in in ADP dpc-459 30 25 situ situ NOUN dpc-459 30 26 and and CCONJ dpc-459 30 27     SPACE dpc-459 30 28 220 220 NUM dpc-459 30 29 ( ( PUNCT dpc-459 30 30 61.6 61.6 NUM dpc-459 30 31 % % NOUN dpc-459 30 32 ) ) PUNCT dpc-459 30 33 were be AUX dpc-459 30 34 invasive invasive ADJ dpc-459 30 35 . . PUNCT dpc-459 31 1 the the DET dpc-459 31 2 median median ADJ dpc-459 31 3 invasion invasion NOUN dpc-459 31 4 thickness thickness NOUN dpc-459 31 5 of of ADP dpc-459 31 6 all all DET dpc-459 31 7 lesions lesion NOUN dpc-459 31 8 was be AUX dpc-459 31 9     SPACE dpc-459 31 10 0.94 0.94 NUM dpc-459 31 11     SPACE dpc-459 31 12 mm mm PROPN dpc-459 31 13 ( ( PUNCT dpc-459 31 14 range range NOUN dpc-459 31 15     SPACE dpc-459 31 16 0.18 0.18 NUM dpc-459 31 17 -10 -10 SYM dpc-459 31 18     SPACE dpc-459 31 19 mm mm PROPN dpc-459 31 20 ) ) PUNCT dpc-459 31 21 . . PUNCT dpc-459 32 1 the the DET dpc-459 32 2 general general ADJ dpc-459 32 3 characteristics characteristic NOUN dpc-459 32 4 of of ADP dpc-459 32 5 the the DET dpc-459 32 6 melanomas melanoma NOUN dpc-459 32 7 are be AUX dpc-459 32 8 given give VERB dpc-459 32 9 in in ADP dpc-459 32 10 table table NOUN dpc-459 32 11     SPACE dpc-459 32 12 1 1 NUM dpc-459 32 13 . . PUNCT dpc-459 33 1 after after ADP dpc-459 33 2 reviewing review VERB dpc-459 33 3 the the DET dpc-459 33 4 histopathologic histopathologic NOUN dpc-459 33 5 slides slide NOUN dpc-459 33 6 , , PUNCT dpc-459 33 7 we we PRON dpc-459 33 8 found find VERB dpc-459 33 9 that that SCONJ dpc-459 33 10     SPACE dpc-459 33 11 284 284 NUM dpc-459 33 12     SPACE dpc-459 33 13 melanomas melanomas NOUN dpc-459 33 14 ( ( PUNCT dpc-459 33 15 79.5 79.5 NUM dpc-459 33 16 % % NOUN dpc-459 33 17 ) ) PUNCT dpc-459 33 18 developed develop VERB dpc-459 33 19 de de X dpc-459 33 20 novo novo NOUN dpc-459 33 21 and and CCONJ dpc-459 33 22     SPACE dpc-459 33 23 31 31 NUM dpc-459 33 24 ( ( PUNCT dpc-459 33 25 8.7 8.7 NUM dpc-459 33 26 % % NOUN dpc-459 33 27 ) ) PUNCT dpc-459 33 28 in in ADP dpc-459 33 29 association association NOUN dpc-459 33 30 with with ADP dpc-459 33 31 a a DET dpc-459 33 32 preexisting preexist VERB dpc-459 33 33 nevus nevus NOUN dpc-459 33 34 . . PUNCT dpc-459 34 1 in in ADP dpc-459 34 2     SPACE dpc-459 34 3 42 42 NUM dpc-459 34 4 ( ( PUNCT dpc-459 34 5 11.8 11.8 NUM dpc-459 34 6 % % NOUN dpc-459 34 7 ) ) PUNCT dpc-459 34 8 cases case NOUN dpc-459 34 9 a a DET dpc-459 34 10 preexisting preexist VERB dpc-459 34 11 nevus nevus NOUN dpc-459 34 12 could could AUX dpc-459 34 13 not not PART dpc-459 34 14 be be AUX dpc-459 34 15 excluded exclude VERB dpc-459 34 16 , , PUNCT dpc-459 34 17 although although SCONJ dpc-459 34 18 the the DET dpc-459 34 19 alternative alternative ADJ dpc-459 34 20 explanation explanation NOUN dpc-459 34 21 that that SCONJ dpc-459 34 22 the the DET dpc-459 34 23 entire entire ADJ dpc-459 34 24 lesion lesion NOUN dpc-459 34 25 represented represent VERB dpc-459 34 26 a a DET dpc-459 34 27 melanoma melanoma NOUN dpc-459 34 28 was be AUX dpc-459 34 29 also also ADV dpc-459 34 30     SPACE dpc-459 34 31 possible possible ADJ dpc-459 34 32 . . PUNCT dpc-459 35 1 introduction introduction NOUN dpc-459 35 2 it it PRON dpc-459 35 3 is be AUX dpc-459 35 4 generally generally ADV dpc-459 35 5 agreed agree VERB dpc-459 35 6 that that SCONJ dpc-459 35 7 the the DET dpc-459 35 8 majority majority NOUN dpc-459 35 9 of of ADP dpc-459 35 10 melanomas melanomas PROPN dpc-459 35 11 arise arise PROPN dpc-459 35 12 de de X dpc-459 35 13 novo novo NOUN dpc-459 35 14 [ [ X dpc-459 35 15 1 1 NUM dpc-459 35 16 - - SYM dpc-459 35 17 5 5 NUM dpc-459 35 18 ] ] PUNCT dpc-459 35 19 . . PUNCT dpc-459 36 1 tsao tsao PROPN dpc-459 36 2 et et PROPN dpc-459 36 3     SPACE dpc-459 36 4 al al PROPN dpc-459 36 5 stated state VERB dpc-459 36 6 that that SCONJ dpc-459 36 7 the the DET dpc-459 36 8 risk risk NOUN dpc-459 36 9 of of ADP dpc-459 36 10 malignant malignant ADJ dpc-459 36 11 transformation transformation NOUN dpc-459 36 12 of of ADP dpc-459 36 13 any any DET dpc-459 36 14 specific specific ADJ dpc-459 36 15 melanocytic melanocytic ADJ dpc-459 36 16 nevus nevus NOUN dpc-459 36 17 is be AUX dpc-459 36 18 low low ADJ dpc-459 36 19 [ [ X dpc-459 36 20 5 5 NUM dpc-459 36 21 ] ] PUNCT dpc-459 36 22 . . PUNCT dpc-459 37 1 some some DET dpc-459 37 2 authors author NOUN dpc-459 37 3 , , PUNCT dpc-459 37 4 however however ADV dpc-459 37 5 , , PUNCT dpc-459 37 6 believe believe VERB dpc-459 37 7 that that SCONJ dpc-459 37 8 melanomas melanoma NOUN dpc-459 37 9 frequently frequently ADV dpc-459 37 10 develop develop VERB dpc-459 37 11 in in ADP dpc-459 37 12 so so ADV dpc-459 37 13 called call VERB dpc-459 37 14 “ " PUNCT dpc-459 37 15 dysplastic dysplastic ADJ dpc-459 37 16 nevi nevi NOUN dpc-459 37 17 ” " PUNCT dpc-459 38 1 [ [ X dpc-459 38 2 6 6 NUM dpc-459 38 3 - - SYM dpc-459 38 4 8 8 NUM dpc-459 38 5 ] ] PUNCT dpc-459 38 6 . . PUNCT dpc-459 39 1 kaddu kaddu PROPN dpc-459 39 2 et et PROPN dpc-459 39 3     SPACE dpc-459 39 4 al al PROPN dpc-459 39 5 , , PUNCT dpc-459 39 6 on on ADP dpc-459 39 7 the the DET dpc-459 39 8 other other ADJ dpc-459 39 9 hand hand NOUN dpc-459 39 10 , , PUNCT dpc-459 39 11 proposed propose VERB dpc-459 39 12 that that SCONJ dpc-459 39 13 small small ADJ dpc-459 39 14 , , PUNCT dpc-459 39 15 superficial superficial ADJ dpc-459 39 16 congenital congenital ADJ dpc-459 39 17 nevi nevi NOUN dpc-459 39 18 might might AUX dpc-459 39 19 play play VERB dpc-459 39 20 an an DET dpc-459 39 21 important important ADJ dpc-459 39 22 role role NOUN dpc-459 39 23 as as ADP dpc-459 39 24 precursor precursor NOUN dpc-459 39 25 lesions lesion NOUN dpc-459 39 26 of of ADP dpc-459 39 27 melanomas melanomas NOUN dpc-459 40 1 [ [ X dpc-459 40 2 3 3 NUM dpc-459 40 3 ] ] PUNCT dpc-459 40 4 . . PUNCT dpc-459 41 1 the the DET dpc-459 41 2 classification classification NOUN dpc-459 41 3 of of ADP dpc-459 41 4 the the DET dpc-459 41 5 type type NOUN dpc-459 41 6 of of ADP dpc-459 41 7 associated associated ADJ dpc-459 41 8 nevus nevus NOUN dpc-459 41 9 is be AUX dpc-459 41 10 difficult difficult ADJ dpc-459 41 11 because because SCONJ dpc-459 41 12 of of ADP dpc-459 41 13 the the DET dpc-459 41 14 lack lack NOUN dpc-459 41 15 of of ADP dpc-459 41 16 a a DET dpc-459 41 17 generally generally ADV dpc-459 41 18 accepted accept VERB dpc-459 41 19 classification classification NOUN dpc-459 41 20 of of ADP dpc-459 41 21 nevi nevi NOUN dpc-459 41 22 . . PUNCT dpc-459 42 1 it it PRON dpc-459 42 2 has have AUX dpc-459 42 3 also also ADV dpc-459 42 4 been be AUX dpc-459 42 5 reported report VERB dpc-459 42 6 that that SCONJ dpc-459 42 7 patients patient NOUN dpc-459 42 8 with with ADP dpc-459 42 9 a a DET dpc-459 42 10 melanoma melanoma NOUN dpc-459 42 11 in in ADP dpc-459 42 12 association association NOUN dpc-459 42 13 with with ADP dpc-459 42 14 a a DET dpc-459 42 15 preexisting preexist VERB dpc-459 42 16 nevus nevus NOUN dpc-459 42 17 are be AUX dpc-459 42 18 significantly significantly ADV dpc-459 42 19 younger young ADJ dpc-459 42 20 than than ADP dpc-459 42 21 patients patient NOUN dpc-459 42 22 with with ADP dpc-459 42 23 de de X dpc-459 42 24 novo novo PROPN dpc-459 42 25 melanomas melanomas NOUN dpc-459 43 1 [ [ X dpc-459 43 2 1,3 1,3 NUM dpc-459 43 3 ] ] PUNCT dpc-459 43 4 . . PUNCT dpc-459 44 1 the the DET dpc-459 44 2 purpose purpose NOUN dpc-459 44 3 of of ADP dpc-459 44 4 this this DET dpc-459 44 5 study study NOUN dpc-459 44 6 was be AUX dpc-459 44 7 to to PART dpc-459 44 8 determine determine VERB dpc-459 44 9 the the DET dpc-459 44 10 frequency frequency NOUN dpc-459 44 11 of of ADP dpc-459 44 12 melanoma melanoma NOUN dpc-459 44 13 in in ADP dpc-459 44 14 association association NOUN dpc-459 44 15 with with ADP dpc-459 44 16 a a DET dpc-459 44 17 preexisting preexist VERB dpc-459 44 18 nevus nevus NOUN dpc-459 44 19 and and CCONJ dpc-459 44 20 to to PART dpc-459 44 21 characterize characterize VERB dpc-459 44 22 the the DET dpc-459 44 23 clinical clinical ADJ dpc-459 44 24 , , PUNCT dpc-459 44 25 histopathologic histopathologic ADJ dpc-459 44 26 and and CCONJ dpc-459 44 27 dermatoscopic dermatoscopic ADJ dpc-459 44 28 appearance appearance NOUN dpc-459 44 29 of of ADP dpc-459 44 30 nevi nevi NOUN dpc-459 44 31 that that PRON dpc-459 44 32 are be AUX dpc-459 44 33 associated associate VERB dpc-459 44 34 with with ADP dpc-459 44 35     SPACE dpc-459 44 36 melanoma melanoma NOUN dpc-459 44 37 . . PUNCT dpc-459 45 1 materials material NOUN dpc-459 45 2 and and CCONJ dpc-459 45 3 methods method NOUN dpc-459 45 4 general general ADJ dpc-459 45 5 characteristics characteristic NOUN dpc-459 45 6 we we PRON dpc-459 45 7 analyzed analyze VERB dpc-459 45 8 a a DET dpc-459 45 9 series series NOUN dpc-459 45 10 of of ADP dpc-459 45 11     SPACE dpc-459 45 12 357 357 NUM dpc-459 45 13     SPACE dpc-459 45 14 consecutive consecutive ADJ dpc-459 45 15 cases case NOUN dpc-459 45 16 of of ADP dpc-459 45 17 histologically histologically ADV dpc-459 45 18 verified verify VERB dpc-459 45 19 melanomas melanomas NOUN dpc-459 45 20 excised excise VERB dpc-459 45 21 between between ADP dpc-459 45 22 january january PROPN dpc-459 45 23     SPACE dpc-459 45 24 1 1 NUM dpc-459 45 25 , , PUNCT dpc-459 45 26 2005 2005 NUM dpc-459 45 27 , , PUNCT dpc-459 45 28 and and CCONJ dpc-459 45 29 december december PROPN dpc-459 45 30     SPACE dpc-459 45 31 31 31 NUM dpc-459 45 32 , , PUNCT dpc-459 45 33 2007 2007 NUM dpc-459 45 34 , , PUNCT dpc-459 45 35 at at ADP dpc-459 45 36 the the DET dpc-459 45 37 department department NOUN dpc-459 45 38 of of ADP dpc-459 45 39 dermatology dermatology NOUN dpc-459 45 40 , , PUNCT dpc-459 45 41 university university PROPN dpc-459 45 42 of of ADP dpc-459 45 43 vienna vienna PROPN dpc-459 45 44 medical medical PROPN dpc-459 45 45 school school PROPN dpc-459 45 46 . . PUNCT dpc-459 46 1 clinical clinical ADJ dpc-459 46 2 images image NOUN dpc-459 46 3 were be AUX dpc-459 46 4 taken take VERB dpc-459 46 5 with with ADP dpc-459 46 6 a a DET dpc-459 46 7 nikon nikon ADJ dpc-459 46 8 d300 d300 ADJ dpc-459 46 9 12.3mp 12.3mp NUM dpc-459 46 10 dslr dslr ADJ dpc-459 46 11 camera camera NOUN dpc-459 46 12 ( ( PUNCT dpc-459 46 13 nikon nikon PROPN dpc-459 46 14 corp corp PROPN dpc-459 46 15 , , PUNCT dpc-459 46 16 tokyo tokyo PROPN dpc-459 46 17 , , PUNCT dpc-459 46 18 japan japan PROPN dpc-459 46 19 ) ) PUNCT dpc-459 46 20 . . PUNCT dpc-459 47 1 dermatoscopic dermatoscopic NOUN dpc-459 47 2 images image NOUN dpc-459 47 3 were be AUX dpc-459 47 4 acquired acquire VERB dpc-459 47 5 either either CCONJ dpc-459 47 6 with with ADP dpc-459 47 7 dermlite dermlite ADJ dpc-459 47 8 fotosystem fotosystem NOUN dpc-459 47 9 ( ( PUNCT dpc-459 47 10 dermlite dermlite NOUN dpc-459 47 11 foto foto NOUN dpc-459 47 12 model model NOUN dpc-459 47 13 combined combine VERB dpc-459 47 14 with with ADP dpc-459 47 15 canong12 canong12 NOUN dpc-459 47 16     SPACE dpc-459 47 17 digital digital PROPN dpc-459 47 18 camera camera NOUN dpc-459 47 19 ; ; PUNCT dpc-459 47 20 3gen 3gen NUM dpc-459 47 21 , , PUNCT dpc-459 47 22 san san PROPN dpc-459 47 23 juan juan PROPN dpc-459 47 24 capistrano capistrano PROPN dpc-459 47 25 , , PUNCT dpc-459 47 26 ca ca PROPN dpc-459 47 27 , , PUNCT dpc-459 47 28 usa usa PROPN dpc-459 47 29 ) ) PUNCT dpc-459 47 30 or or CCONJ dpc-459 47 31 with with ADP dpc-459 47 32 a a DET dpc-459 47 33 digital digital ADJ dpc-459 47 34 dermatoscopic dermatoscopic ADJ dpc-459 47 35 imaging imaging NOUN dpc-459 47 36 system system NOUN dpc-459 47 37 molemax molemax ADJ dpc-459 47 38 iitm iitm NOUN dpc-459 47 39 ( ( PUNCT dpc-459 47 40 derma derma NOUN dpc-459 47 41 medical medical ADJ dpc-459 47 42 systems system NOUN dpc-459 47 43 , , PUNCT dpc-459 47 44 vienna vienna PROPN dpc-459 47 45 , , PUNCT dpc-459 47 46 austria austria PROPN dpc-459 47 47 ) ) PUNCT dpc-459 47 48 . . PUNCT dpc-459 48 1 histopathologic histopathologic ADJ dpc-459 48 2 assessment assessment NOUN dpc-459 48 3 and and CCONJ dpc-459 48 4 review review NOUN dpc-459 48 5 of of ADP dpc-459 48 6 images image NOUN dpc-459 48 7 all all DET dpc-459 48 8 cases case NOUN dpc-459 48 9 were be AUX dpc-459 48 10 subjected subject VERB dpc-459 48 11 to to ADP dpc-459 48 12 standard standard ADJ dpc-459 48 13 histopathologic histopathologic ADJ dpc-459 48 14 processing processing NOUN dpc-459 48 15 . . PUNCT dpc-459 49 1 histopathologic histopathologic PROPN dpc-459 49 2 slides slide NOUN dpc-459 49 3 were be AUX dpc-459 49 4 reviewed review VERB dpc-459 49 5 by by ADP dpc-459 49 6 the the DET dpc-459 49 7 study study NOUN dpc-459 49 8 authors author NOUN dpc-459 49 9 and and CCONJ dpc-459 49 10 classified classify VERB dpc-459 49 11 into into ADP dpc-459 49 12 the the DET dpc-459 49 13 following follow VERB dpc-459 49 14 subgroups subgroup NOUN dpc-459 49 15 : : PUNCT dpc-459 49 16 ( ( PUNCT dpc-459 49 17 1 1 X dpc-459 49 18 ) ) PUNCT dpc-459 49 19 de de PROPN dpc-459 49 20 novo novo NOUN dpc-459 49 21 melanomas melanomas PROPN dpc-459 49 22 , , PUNCT dpc-459 49 23 ( ( PUNCT dpc-459 49 24 2 2 X dpc-459 49 25 ) ) PUNCT dpc-459 49 26 melanomas melanomas NOUN dpc-459 49 27 arising arise VERB dpc-459 49 28 in in ADP dpc-459 49 29 a a DET dpc-459 49 30 preexisting preexist VERB dpc-459 49 31 nevus nevus NOUN dpc-459 49 32 , , PUNCT dpc-459 49 33 and and CCONJ dpc-459 49 34 ( ( PUNCT dpc-459 49 35 3 3 X dpc-459 49 36 ) ) PUNCT dpc-459 49 37 non non ADJ dpc-459 49 38 - - ADJ dpc-459 49 39 decidable decidable ADJ dpc-459 49 40 cases case NOUN dpc-459 49 41 . . PUNCT dpc-459 50 1 histopathologic histopathologic ADJ dpc-459 50 2 review review NOUN dpc-459 50 3 of of ADP dpc-459 50 4 the the DET dpc-459 50 5 case case NOUN dpc-459 50 6 was be AUX dpc-459 50 7 performed perform VERB dpc-459 50 8 without without ADP dpc-459 50 9 knowledge knowledge NOUN dpc-459 50 10 of of ADP dpc-459 50 11 the the DET dpc-459 50 12 respective respective ADJ dpc-459 50 13 clinical clinical ADJ dpc-459 50 14 or or CCONJ dpc-459 50 15 dermatoscopic dermatoscopic ADJ dpc-459 50 16 images image NOUN dpc-459 50 17 . . PUNCT dpc-459 51 1 we we PRON dpc-459 51 2 used use VERB dpc-459 51 3 standard standard ADJ dpc-459 51 4 histopathologic histopathologic ADJ dpc-459 51 5 criteria criterion NOUN dpc-459 51 6 to to PART dpc-459 51 7 differentiate differentiate VERB dpc-459 51 8 between between ADP dpc-459 51 9 melanomas melanoma NOUN dpc-459 51 10 and and CCONJ dpc-459 51 11 nevi nevi PROPN dpc-459 51 12 . . PUNCT dpc-459 52 1 for for ADP dpc-459 52 2 the the DET dpc-459 52 3 classification classification NOUN dpc-459 52 4 of of ADP dpc-459 52 5 associated associated ADJ dpc-459 52 6 nevi nevi PROPN dpc-459 52 7 , , PUNCT dpc-459 52 8 we we PRON dpc-459 52 9 used use VERB dpc-459 52 10 the the DET dpc-459 52 11 nevus nevus ADJ dpc-459 52 12 classification classification NOUN dpc-459 52 13 according accord VERB dpc-459 52 14 to to ADP dpc-459 52 15 ackerman ackerman NOUN dpc-459 52 16 and and CCONJ dpc-459 52 17 differentiated differentiate VERB dpc-459 52 18 between between ADP dpc-459 52 19 clark clark NOUN dpc-459 52 20 nevi nevi PROPN dpc-459 52 21 , , PUNCT dpc-459 52 22 superficial superficial ADJ dpc-459 52 23 congenital congenital ADJ dpc-459 52 24 nevi nevi NOUN dpc-459 52 25 ( ( PUNCT dpc-459 52 26 ackerman ackerman NOUN dpc-459 52 27 nevi nevi PROPN dpc-459 52 28 ) ) PUNCT dpc-459 52 29 , , PUNCT dpc-459 52 30 and and CCONJ dpc-459 52 31 “ " PUNCT dpc-459 52 32 superficial superficial ADJ dpc-459 52 33 and and CCONJ dpc-459 52 34 deep deep ADJ dpc-459 52 35 ” " PUNCT dpc-459 52 36 congenital congenital ADJ dpc-459 52 37 nevi nevi NOUN dpc-459 52 38 ( ( PUNCT dpc-459 52 39 zitelli zitelli NOUN dpc-459 52 40 nevi nevi X dpc-459 52 41 ) ) PUNCT dpc-459 53 1 [ [ X dpc-459 53 2 9 9 NUM dpc-459 53 3 ] ] PUNCT dpc-459 53 4 . . PUNCT dpc-459 54 1 a a DET dpc-459 54 2 schematic schematic ADJ dpc-459 54 3 presentation presentation NOUN dpc-459 54 4 of of ADP dpc-459 54 5 the the DET dpc-459 54 6 histopathologic histopathologic ADJ dpc-459 54 7 characteristics characteristic NOUN dpc-459 54 8 of of ADP dpc-459 54 9 these these DET dpc-459 54 10 nevi nevi NOUN dpc-459 54 11 is be AUX dpc-459 54 12 given give VERB dpc-459 54 13 in in ADP dpc-459 54 14 figure figure NOUN dpc-459 54 15     SPACE dpc-459 54 16 1 1 NUM dpc-459 54 17 . . PUNCT dpc-459 55 1 the the DET dpc-459 55 2 two two NUM dpc-459 55 3 study study NOUN dpc-459 55 4 authors author NOUN dpc-459 55 5 reviewed review VERB dpc-459 55 6 all all DET dpc-459 55 7 available available ADJ dpc-459 55 8 clinical clinical ADJ dpc-459 55 9 and and CCONJ dpc-459 55 10 dermafigure dermafigure NOUN dpc-459 55 11 1 1 NUM dpc-459 55 12 . . PUNCT dpc-459 55 13 schematic schematic ADJ dpc-459 55 14 drawings drawing NOUN dpc-459 55 15 of of ADP dpc-459 55 16 histomorphologic histomorphologic ADJ dpc-459 55 17 patterns pattern NOUN dpc-459 55 18 of of ADP dpc-459 55 19 nevi nevi NOUN dpc-459 55 20 . . PUNCT dpc-459 56 1 ( ( PUNCT dpc-459 56 2 a a X dpc-459 56 3 ) ) PUNCT dpc-459 56 4 clark clark NOUN dpc-459 56 5 nevus nevus NOUN dpc-459 56 6 ; ; PUNCT dpc-459 56 7 ( ( PUNCT dpc-459 56 8 b b X dpc-459 56 9 ) ) PUNCT dpc-459 56 10 superficial superficial ADJ dpc-459 56 11 congenital congenital ADJ dpc-459 56 12 nevus nevu NOUN dpc-459 56 13 ; ; PUNCT dpc-459 56 14 ( ( PUNCT dpc-459 56 15 c c X dpc-459 56 16 ) ) PUNCT dpc-459 56 17 superficial superficial ADJ dpc-459 56 18 or or CCONJ dpc-459 56 19 deep deep ADJ dpc-459 56 20 congenital congenital ADJ dpc-459 56 21 nevus nevus NOUN dpc-459 56 22 . . PUNCT dpc-459 57 1 106 106 NUM dpc-459 57 2 research research NOUN dpc-459 57 3 | | ADV dpc-459 57 4 dermatol dermatol NOUN dpc-459 57 5 pract pract NOUN dpc-459 57 6 concept concept NOUN dpc-459 57 7 2018;8(2):7 2018;8(2):7 NOUN dpc-459 57 8 the the DET dpc-459 57 9 nevus nevus NOUN dpc-459 57 10 was be AUX dpc-459 57 11 of of ADP dpc-459 57 12 the the DET dpc-459 57 13 congenital congenital ADJ dpc-459 57 14 type type NOUN dpc-459 57 15 . . PUNCT dpc-459 58 1 dermatoscopic dermatoscopic NOUN dpc-459 58 2 images image NOUN dpc-459 58 3 were be AUX dpc-459 58 4 available available ADJ dpc-459 58 5 in in ADP dpc-459 58 6     SPACE dpc-459 58 7 5 5 NUM dpc-459 58 8     SPACE dpc-459 58 9 nevus nevus NOUN dpc-459 58 10 - - PUNCT dpc-459 58 11 associated associate VERB dpc-459 58 12 melanomas melanoma NOUN dpc-459 58 13 . . PUNCT dpc-459 59 1 the the DET dpc-459 59 2 clinical clinical ADJ dpc-459 59 3 , , PUNCT dpc-459 59 4 dermatoscopic dermatoscopic ADJ dpc-459 59 5 and and CCONJ dpc-459 59 6 histopathologic histopathologic NOUN dpc-459 59 7 images image NOUN dpc-459 59 8 of of ADP dpc-459 59 9 nevus nevus NOUN dpc-459 59 10 - - PUNCT dpc-459 59 11 associated associate VERB dpc-459 59 12 melanomas melanoma NOUN dpc-459 59 13 are be AUX dpc-459 59 14 shown show VERB dpc-459 59 15 in in ADP dpc-459 59 16 figures figure NOUN dpc-459 59 17     SPACE dpc-459 59 18 3 3 NUM dpc-459 59 19     SPACE dpc-459 59 20 and and CCONJ dpc-459 59 21     SPACE dpc-459 59 22 4 4 NUM dpc-459 59 23 . . X dpc-459 59 24 figure figure VERB dpc-459 59 25     SPACE dpc-459 59 26 5 5 NUM dpc-459 59 27     SPACE dpc-459 59 28 shows show VERB dpc-459 59 29 clinical clinical ADJ dpc-459 59 30 and and CCONJ dpc-459 59 31 dermatoscopic dermatoscopic ADJ dpc-459 59 32 images image NOUN dpc-459 59 33 of of ADP dpc-459 59 34     SPACE dpc-459 59 35 2 2 NUM dpc-459 59 36     SPACE dpc-459 59 37 melanomas melanomas NOUN dpc-459 59 38 arising arise VERB dpc-459 59 39 in in ADP dpc-459 59 40 a a DET dpc-459 59 41 superficial superficial ADJ dpc-459 59 42 and and CCONJ dpc-459 59 43 deep deep ADJ dpc-459 59 44 congenital congenital ADJ dpc-459 59 45 nevus nevu NOUN dpc-459 59 46 ; ; PUNCT dpc-459 59 47 differences difference NOUN dpc-459 59 48 between between ADP dpc-459 59 49 de de X dpc-459 59 50 novo novo NOUN dpc-459 59 51 and and CCONJ dpc-459 59 52 nevus nevus ADJ dpc-459 59 53 - - PUNCT dpc-459 59 54 associated associate VERB dpc-459 59 55 melanomas melanoma NOUN dpc-459 59 56 the the DET dpc-459 59 57 mean mean ADJ dpc-459 59 58 age age NOUN dpc-459 59 59 of of ADP dpc-459 59 60 patients patient NOUN dpc-459 59 61 diagnosed diagnose VERB dpc-459 59 62 with with ADP dpc-459 59 63 de de X dpc-459 59 64 novo novo PROPN dpc-459 59 65 melanomas melanomas PROPN dpc-459 59 66 was be AUX dpc-459 59 67     SPACE dpc-459 59 68 68.2 68.2 NUM dpc-459 59 69     SPACE dpc-459 59 70 years year NOUN dpc-459 59 71 ( ( PUNCT dpc-459 59 72 sd sd NOUN dpc-459 59 73 : : PUNCT dpc-459 59 74 14.8 14.8 NUM dpc-459 59 75     SPACE dpc-459 59 76 years year NOUN dpc-459 59 77 ) ) PUNCT dpc-459 59 78 . . PUNCT dpc-459 60 1 patients patient NOUN dpc-459 60 2 with with ADP dpc-459 60 3 a a DET dpc-459 60 4 melanoma melanoma NOUN dpc-459 60 5 in in ADP dpc-459 60 6 association association NOUN dpc-459 60 7 with with ADP dpc-459 60 8 a a DET dpc-459 60 9 preexisting preexist VERB dpc-459 60 10 nevus nevus NOUN dpc-459 60 11 were be AUX dpc-459 60 12 significantly significantly ADV dpc-459 60 13 younger young ADJ dpc-459 60 14 with with ADP dpc-459 60 15 a a DET dpc-459 60 16 mean mean ADJ dpc-459 60 17 age age NOUN dpc-459 60 18 of of ADP dpc-459 60 19     SPACE dpc-459 60 20 54.9 54.9 NUM dpc-459 60 21     SPACE dpc-459 60 22 years year NOUN dpc-459 60 23 ( ( PUNCT dpc-459 60 24 sd sd NOUN dpc-459 60 25 : : PUNCT dpc-459 60 26 16.3 16.3 NUM dpc-459 60 27     SPACE dpc-459 60 28 years year NOUN dpc-459 60 29 , , PUNCT dpc-459 60 30 p<0.001 p<0.001 PROPN dpc-459 60 31 ) ) PUNCT dpc-459 60 32 . . PUNCT dpc-459 61 1 the the DET dpc-459 61 2 frequency frequency NOUN dpc-459 61 3 of of ADP dpc-459 61 4 in in ADP dpc-459 61 5 situ situ ADJ dpc-459 61 6 melanomas melanomas NOUN dpc-459 61 7 was be AUX dpc-459 61 8 significantly significantly ADV dpc-459 61 9 higher high ADJ dpc-459 61 10 in in ADP dpc-459 61 11 the the DET dpc-459 61 12 group group NOUN dpc-459 61 13 of of ADP dpc-459 61 14 de de X dpc-459 61 15 novo novo PROPN dpc-459 61 16 melanomas melanomas PROPN dpc-459 61 17 ( ( PUNCT dpc-459 61 18 40.1 40.1 NUM dpc-459 61 19 % % NOUN dpc-459 61 20 , , PUNCT dpc-459 61 21 n=114 n=114 PROPN dpc-459 61 22 ) ) PUNCT dpc-459 61 23 than than ADP dpc-459 61 24 in in ADP dpc-459 61 25 the the DET dpc-459 61 26 group group NOUN dpc-459 61 27 of of ADP dpc-459 61 28 melanomas melanomas PROPN dpc-459 61 29 in in ADP dpc-459 61 30 association association NOUN dpc-459 61 31 with with ADP dpc-459 61 32 a a DET dpc-459 61 33 preexisting preexist VERB dpc-459 61 34 nevus nevus NOUN dpc-459 61 35 ( ( PUNCT dpc-459 61 36 16.1 16.1 NUM dpc-459 61 37 % % NOUN dpc-459 61 38 , , PUNCT dpc-459 61 39 n=5 n=5 PROPN dpc-459 61 40 , , PUNCT dpc-459 61 41 p<0.001 p<0.001 PROPN dpc-459 61 42 ) ) PUNCT dpc-459 61 43 . . PUNCT dpc-459 62 1 the the DET dpc-459 62 2 median median ADJ dpc-459 62 3 tumor tumor NOUN dpc-459 62 4 thickness thickness NOUN dpc-459 62 5 of of ADP dpc-459 62 6 invasive invasive ADJ dpc-459 62 7 melanomas melanomas NOUN dpc-459 62 8 in in ADP dpc-459 62 9 association association NOUN dpc-459 62 10 with with ADP dpc-459 62 11 a a DET dpc-459 62 12 preexisting preexist VERB dpc-459 62 13 nevus nevus NOUN dpc-459 62 14 was be AUX dpc-459 62 15     SPACE dpc-459 62 16 0.85 0.85 NUM dpc-459 62 17     SPACE dpc-459 62 18 mm mm PROPN dpc-459 62 19 ( ( PUNCT dpc-459 62 20 range:0.3 range:0.3 PROPN dpc-459 62 21 – – PUNCT dpc-459 62 22 7.0 7.0 NUM dpc-459 62 23     SPACE dpc-459 62 24 mm mm NOUN dpc-459 62 25 ) ) PUNCT dpc-459 62 26 and and CCONJ dpc-459 62 27 not not PART dpc-459 62 28 significantly significantly ADV dpc-459 62 29 different different ADJ dpc-459 62 30 from from ADP dpc-459 62 31 de de PROPN dpc-459 62 32 novo novo PROPN dpc-459 62 33 melanomas melanomas PROPN dpc-459 62 34     SPACE dpc-459 62 35 0.80 0.80 NUM dpc-459 62 36     SPACE dpc-459 62 37 mm mm PROPN dpc-459 62 38 ( ( PUNCT dpc-459 62 39 range range NOUN dpc-459 62 40 : : PUNCT dpc-459 62 41 0.2–10.0 0.2–10.0 NOUN dpc-459 62 42     SPACE dpc-459 62 43 mm mm PROPN dpc-459 62 44 , , PUNCT dpc-459 62 45 p=0.99 p=0.99 PROPN dpc-459 62 46 ) ) PUNCT dpc-459 62 47 . . PUNCT dpc-459 63 1 histomorphologically histomorphologically ADV dpc-459 63 2 the the DET dpc-459 63 3 associated associated ADJ dpc-459 63 4 nevus nevus NOUN dpc-459 63 5 was be AUX dpc-459 63 6 a a DET dpc-459 63 7 “ " PUNCT dpc-459 63 8 superficial superficial ADJ dpc-459 63 9 ” " PUNCT dpc-459 63 10 or or CCONJ dpc-459 63 11 “ " PUNCT dpc-459 63 12 superficial superficial ADJ dpc-459 63 13 and and CCONJ dpc-459 63 14 deep deep ADJ dpc-459 63 15 ” " PUNCT dpc-459 63 16 congenital congenital ADJ dpc-459 63 17 nevus nevus NOUN dpc-459 63 18 in in ADP dpc-459 63 19     SPACE dpc-459 63 20 27 27 NUM dpc-459 63 21     SPACE dpc-459 63 22 cases case NOUN dpc-459 63 23 ( ( PUNCT dpc-459 63 24 87 87 NUM dpc-459 63 25 % % NOUN dpc-459 63 26 ) ) PUNCT dpc-459 63 27 and and CCONJ dpc-459 63 28 a a DET dpc-459 63 29 clark clark NOUN dpc-459 63 30 nevus nevus NOUN dpc-459 63 31 in in ADP dpc-459 63 32     SPACE dpc-459 63 33 4 4 NUM dpc-459 63 34     SPACE dpc-459 63 35 cases case NOUN dpc-459 63 36 ( ( PUNCT dpc-459 63 37 13 13 NUM dpc-459 63 38 % % NOUN dpc-459 63 39 ) ) PUNCT dpc-459 63 40 . . PUNCT dpc-459 64 1 nevus nevus PROPN dpc-459 64 2 associated associate VERB dpc-459 64 3 melanomas melanomas PROPN dpc-459 64 4 more more ADV dpc-459 64 5 frequently frequently ADV dpc-459 64 6 occurred occur VERB dpc-459 64 7 on on ADP dpc-459 64 8 the the DET dpc-459 64 9 trunk trunk NOUN dpc-459 64 10 than than ADP dpc-459 64 11 de de X dpc-459 64 12 novo novo PROPN dpc-459 64 13 melanomas melanomas PROPN dpc-459 64 14 ( ( PUNCT dpc-459 64 15 58.1 58.1 NUM dpc-459 64 16 % % NOUN dpc-459 64 17 versus versus ADP dpc-459 64 18     SPACE dpc-459 64 19 27.4 27.4 NUM dpc-459 64 20 % % NOUN dpc-459 64 21 , , PUNCT dpc-459 64 22 p=0.004 p=0.004 PROPN dpc-459 64 23 ) ) PUNCT dpc-459 64 24 . . PUNCT dpc-459 65 1 the the DET dpc-459 65 2 mean mean PROPN dpc-459 65 3 survival survival NOUN dpc-459 65 4 was be AUX dpc-459 65 5     SPACE dpc-459 65 6 8.9 8.9 NUM dpc-459 65 7     SPACE dpc-459 65 8 years year NOUN dpc-459 65 9 ( ( PUNCT dpc-459 65 10 95 95 NUM dpc-459 65 11 % % NOUN dpc-459 65 12 ci ci NOUN dpc-459 65 13 : : PUNCT dpc-459 65 14 8.6–9.4 8.6–9.4 NOUN dpc-459 65 15     SPACE dpc-459 65 16 years year NOUN dpc-459 65 17 ) ) PUNCT dpc-459 65 18 in in ADP dpc-459 65 19 the the DET dpc-459 65 20 group group NOUN dpc-459 65 21 of of ADP dpc-459 65 22 nevus nevus NOUN dpc-459 65 23 - - PUNCT dpc-459 65 24 associated associate VERB dpc-459 65 25 melanomas melanomas NOUN dpc-459 65 26 and and CCONJ dpc-459 65 27     SPACE dpc-459 65 28 7.7 7.7 NUM dpc-459 65 29     SPACE dpc-459 65 30 years year NOUN dpc-459 65 31     SPACE dpc-459 65 32 95 95 NUM dpc-459 65 33 % % NOUN dpc-459 65 34 ci ci NOUN dpc-459 65 35 : : PUNCT dpc-459 65 36 7.3 7.3 NUM dpc-459 65 37 – – PUNCT dpc-459 65 38 8.0 8.0 NUM dpc-459 65 39     SPACE dpc-459 65 40 years year NOUN dpc-459 65 41 ) ) PUNCT dpc-459 65 42 in in ADP dpc-459 65 43 the the DET dpc-459 65 44 group group NOUN dpc-459 65 45 of of ADP dpc-459 65 46 de de PROPN dpc-459 65 47 novo novo PROPN dpc-459 65 48 melanomas melanomas PROPN dpc-459 65 49 . . PUNCT dpc-459 66 1 age age NOUN dpc-459 66 2 ( ( PUNCT dpc-459 66 3 hazard hazard NOUN dpc-459 66 4 ratio ratio NOUN dpc-459 66 5 : : PUNCT dpc-459 66 6 1.06 1.06 NUM dpc-459 66 7 , , PUNCT dpc-459 66 8 95 95 NUM dpc-459 66 9 % % NOUN dpc-459 66 10 ci ci NOUN dpc-459 66 11 : : PUNCT dpc-459 66 12 1.03–1.08 1.03–1.08 NUM dpc-459 66 13 , , PUNCT dpc-459 66 14 p<0.001 p<0.001 ADJ dpc-459 66 15 ) ) PUNCT dpc-459 66 16 and and CCONJ dpc-459 66 17 invasion invasion NOUN dpc-459 66 18 thickness thickness NOUN dpc-459 66 19 ( ( PUNCT dpc-459 66 20 hazard hazard NOUN dpc-459 66 21 ratio ratio NOUN dpc-459 66 22 : : PUNCT dpc-459 66 23 1.37 1.37 NUM dpc-459 66 24 , , PUNCT dpc-459 66 25 95 95 NUM dpc-459 66 26 % % NOUN dpc-459 66 27 ci ci NOUN dpc-459 66 28 : : PUNCT dpc-459 66 29 1.19–1.58 1.19–1.58 NUM dpc-459 66 30 , , PUNCT dpc-459 66 31 p<0.001 p<0.001 PUNCT dpc-459 66 32 ) ) PUNCT dpc-459 66 33 were be AUX dpc-459 66 34 independent independent ADJ dpc-459 66 35 predictors predictor NOUN dpc-459 66 36 of of ADP dpc-459 66 37 survival survival NOUN dpc-459 66 38 but but CCONJ dpc-459 66 39 not not PART dpc-459 66 40 of of ADP dpc-459 66 41 whether whether SCONJ dpc-459 66 42 the the DET dpc-459 66 43 melanoma melanoma NOUN dpc-459 66 44 was be AUX dpc-459 66 45 nevus nevus ADJ dpc-459 66 46 - - PUNCT dpc-459 66 47 associated associate VERB dpc-459 66 48 or or CCONJ dpc-459 66 49 de de X dpc-459 66 50 novo novo NOUN dpc-459 66 51 ( ( PUNCT dpc-459 66 52 hazard hazard NOUN dpc-459 66 53 ratio ratio NOUN dpc-459 66 54 : : PUNCT dpc-459 66 55 4.99 4.99 NUM dpc-459 66 56 , , PUNCT dpc-459 66 57 95 95 NUM dpc-459 66 58 % % NOUN dpc-459 66 59 ci ci NOUN dpc-459 66 60 : : PUNCT dpc-459 66 61 0.67–37.23 0.67–37.23 NOUN dpc-459 66 62 , , PUNCT dpc-459 66 63 p=0.12 p=0.12 NOUN dpc-459 66 64 ) ) PUNCT dpc-459 66 65 clinical clinical ADJ dpc-459 66 66 and and CCONJ dpc-459 66 67 dermatoscopic dermatoscopic ADJ dpc-459 66 68 morphology morphology NOUN dpc-459 66 69 clinical clinical ADJ dpc-459 66 70 or or CCONJ dpc-459 66 71 dermatoscopic dermatoscopic ADJ dpc-459 66 72 images image NOUN dpc-459 66 73 were be AUX dpc-459 66 74 available available ADJ dpc-459 66 75 in in ADP dpc-459 66 76     SPACE dpc-459 66 77 17 17 NUM dpc-459 66 78     SPACE dpc-459 66 79 cases case NOUN dpc-459 66 80 of of ADP dpc-459 66 81 nevus nevus NOUN dpc-459 66 82 - - PUNCT dpc-459 66 83 associated associate VERB dpc-459 66 84 melanomas melanoma NOUN dpc-459 66 85 , , PUNCT dpc-459 66 86 and and CCONJ dpc-459 66 87 the the DET dpc-459 66 88 preexisting preexist VERB dpc-459 66 89 nevus nevus NOUN dpc-459 66 90 was be AUX dpc-459 66 91 visible visible ADJ dpc-459 66 92 clinically clinically ADV dpc-459 66 93 or or CCONJ dpc-459 66 94 dermatoscopically dermatoscopically ADV dpc-459 66 95 in in ADP dpc-459 66 96     SPACE dpc-459 66 97 11 11 NUM dpc-459 66 98     SPACE dpc-459 66 99 cases case NOUN dpc-459 66 100 . . PUNCT dpc-459 67 1 the the DET dpc-459 67 2 clinical clinical ADJ dpc-459 67 3 images image NOUN dpc-459 67 4 of of ADP dpc-459 67 5     SPACE dpc-459 67 6 4 4 NUM dpc-459 67 7     SPACE dpc-459 67 8 nevus nevus NOUN dpc-459 67 9 - - PUNCT dpc-459 67 10 associated associate VERB dpc-459 67 11 melanomas melanomas NOUN dpc-459 67 12 in in ADP dpc-459 67 13 figure figure NOUN dpc-459 67 14     SPACE dpc-459 67 15 2 2 NUM dpc-459 67 16     SPACE dpc-459 67 17 show show VERB dpc-459 67 18 nevus nevus ADJ dpc-459 67 19 remnants remnant NOUN dpc-459 67 20 , , PUNCT dpc-459 67 21 mostly mostly ADV dpc-459 67 22 at at ADP dpc-459 67 23 the the DET dpc-459 67 24 periphery periphery NOUN dpc-459 67 25 of of ADP dpc-459 67 26 the the DET dpc-459 67 27 lesion lesion NOUN dpc-459 67 28 . . PUNCT dpc-459 68 1 in in ADP dpc-459 68 2 all all DET dpc-459 68 3     SPACE dpc-459 68 4 4 4 NUM dpc-459 68 5     SPACE dpc-459 68 6 cases case NOUN dpc-459 68 7 table table NOUN dpc-459 68 8 1 1 NUM dpc-459 68 9 . . PUNCT dpc-459 68 10 general general ADJ dpc-459 68 11 characteristics characteristic NOUN dpc-459 68 12 of of ADP dpc-459 68 13 cases case NOUN dpc-459 68 14 de de X dpc-459 68 15 novo novo PROPN dpc-459 68 16 melanomas melanomas PROPN dpc-459 68 17 nevus nevus PROPN dpc-459 68 18 associated associate VERB dpc-459 68 19 melanomas melanomas PROPN dpc-459 69 1 undecided undecided ADJ dpc-459 69 2 n n CCONJ dpc-459 69 3 ( ( PUNCT dpc-459 69 4 % % INTJ dpc-459 69 5 ) ) PUNCT dpc-459 69 6 284 284 NUM dpc-459 69 7 ( ( PUNCT dpc-459 69 8 79.5 79.5 NUM dpc-459 69 9 % % NOUN dpc-459 69 10 ) ) PUNCT dpc-459 69 11 31 31 NUM dpc-459 69 12 ( ( PUNCT dpc-459 69 13 8.7 8.7 NUM dpc-459 69 14 % % NOUN dpc-459 69 15 ) ) PUNCT dpc-459 69 16 42 42 NUM dpc-459 69 17 ( ( PUNCT dpc-459 69 18 11.8 11.8 NUM dpc-459 69 19 % % NOUN dpc-459 69 20 ) ) PUNCT dpc-459 70 1 mean mean NOUN dpc-459 70 2 age age NOUN dpc-459 70 3 ( ( PUNCT dpc-459 70 4 years year NOUN dpc-459 70 5 ) ) PUNCT dpc-459 70 6 68.3 68.3 NUM dpc-459 70 7 54.9 54.9 NUM dpc-459 70 8 62.7 62.7 NUM dpc-459 70 9 gender gender NOUN dpc-459 70 10 male male NOUN dpc-459 70 11 141 141 NUM dpc-459 70 12 ( ( PUNCT dpc-459 70 13 49.6 49.6 NUM dpc-459 70 14 % % NOUN dpc-459 70 15 ) ) PUNCT dpc-459 70 16 20 20 NUM dpc-459 70 17 ( ( PUNCT dpc-459 70 18 64.5 64.5 NUM dpc-459 70 19 % % NOUN dpc-459 70 20 ) ) PUNCT dpc-459 70 21 33 33 NUM dpc-459 70 22 ( ( PUNCT dpc-459 70 23 78.6 78.6 NUM dpc-459 70 24 % % NOUN dpc-459 70 25 ) ) PUNCT dpc-459 70 26 female female NOUN dpc-459 70 27 143 143 NUM dpc-459 70 28 ( ( PUNCT dpc-459 70 29 50.4 50.4 NUM dpc-459 70 30 % % NOUN dpc-459 70 31 ) ) PUNCT dpc-459 70 32 11 11 NUM dpc-459 70 33 ( ( PUNCT dpc-459 70 34 35.5 35.5 NUM dpc-459 70 35 % % NOUN dpc-459 70 36 ) ) PUNCT dpc-459 70 37 9 9 NUM dpc-459 70 38 ( ( PUNCT dpc-459 70 39 21.4 21.4 NUM dpc-459 70 40 % % NOUN dpc-459 70 41 ) ) PUNCT dpc-459 70 42 anatomic anatomic ADJ dpc-459 70 43 site site NOUN dpc-459 70 44 head head NOUN dpc-459 70 45 and and CCONJ dpc-459 70 46 neck neck NOUN dpc-459 70 47 92 92 NUM dpc-459 70 48 ( ( PUNCT dpc-459 70 49 32.4 32.4 NUM dpc-459 70 50 % % NOUN dpc-459 70 51 ) ) PUNCT dpc-459 70 52 4 4 NUM dpc-459 70 53 ( ( PUNCT dpc-459 70 54 12.9 12.9 NUM dpc-459 70 55 % % NOUN dpc-459 70 56 ) ) PUNCT dpc-459 70 57 3 3 NUM dpc-459 70 58 ( ( PUNCT dpc-459 70 59 7.1 7.1 NUM dpc-459 70 60 % % NOUN dpc-459 70 61 ) ) PUNCT dpc-459 70 62 trunk trunk NOUN dpc-459 70 63 78 78 NUM dpc-459 70 64 ( ( PUNCT dpc-459 70 65 27.5 27.5 NUM dpc-459 70 66 % % NOUN dpc-459 70 67 ) ) PUNCT dpc-459 70 68 18 18 NUM dpc-459 70 69 ( ( PUNCT dpc-459 70 70 58.1 58.1 NUM dpc-459 70 71 % % NOUN dpc-459 70 72 ) ) PUNCT dpc-459 70 73 22 22 NUM dpc-459 70 74 ( ( PUNCT dpc-459 70 75 52.4 52.4 NUM dpc-459 70 76 % % NOUN dpc-459 70 77 ) ) PUNCT dpc-459 70 78 upper upper ADJ dpc-459 70 79 extremities extremity NOUN dpc-459 70 80 51 51 NUM dpc-459 70 81 ( ( PUNCT dpc-459 70 82 17.9 17.9 NUM dpc-459 70 83 % % NOUN dpc-459 70 84 ) ) PUNCT dpc-459 70 85 5 5 NUM dpc-459 70 86 ( ( PUNCT dpc-459 70 87 16.1 16.1 NUM dpc-459 70 88 % % NOUN dpc-459 70 89 ) ) PUNCT dpc-459 70 90 9 9 NUM dpc-459 70 91 ( ( PUNCT dpc-459 70 92 21.4 21.4 NUM dpc-459 70 93 % % NOUN dpc-459 70 94 ) ) PUNCT dpc-459 70 95 lower low ADJ dpc-459 70 96 extremities extremity NOUN dpc-459 70 97 63 63 NUM dpc-459 70 98 ( ( PUNCT dpc-459 70 99 22.2 22.2 NUM dpc-459 70 100 % % NOUN dpc-459 70 101 ) ) PUNCT dpc-459 70 102 4 4 NUM dpc-459 70 103 ( ( PUNCT dpc-459 70 104 12.9 12.9 NUM dpc-459 70 105 % % NOUN dpc-459 70 106 ) ) PUNCT dpc-459 70 107 8 8 NUM dpc-459 70 108 ( ( PUNCT dpc-459 70 109 19.1 19.1 NUM dpc-459 70 110 % % NOUN dpc-459 70 111 ) ) PUNCT dpc-459 70 112 histopathologic histopathologic PROPN dpc-459 70 113 criteria criterion NOUN dpc-459 70 114 median median ADJ dpc-459 70 115 invasion invasion NOUN dpc-459 70 116 thickness thickness NOUN dpc-459 70 117 ( ( PUNCT dpc-459 70 118 mm mm NOUN dpc-459 70 119 ) ) PUNCT dpc-459 70 120 0.80 0.80 NUM dpc-459 70 121 0.85 0.85 NUM dpc-459 70 122 0.60 0.60 NUM dpc-459 70 123 in in ADP dpc-459 70 124 situ situ ADJ dpc-459 70 125 melanomas melanomas NOUN dpc-459 70 126 ( ( PUNCT dpc-459 70 127 n n CCONJ dpc-459 70 128 , , PUNCT dpc-459 70 129 % % INTJ dpc-459 70 130 ) ) PUNCT dpc-459 70 131 114 114 NUM dpc-459 70 132 ( ( PUNCT dpc-459 70 133 40.1 40.1 NUM dpc-459 70 134 % % NOUN dpc-459 70 135 ) ) PUNCT dpc-459 70 136 5 5 NUM dpc-459 70 137 ( ( PUNCT dpc-459 70 138 16.1 16.1 NUM dpc-459 70 139 % % NOUN dpc-459 70 140 ) ) PUNCT dpc-459 70 141 19 19 NUM dpc-459 70 142 ( ( PUNCT dpc-459 70 143 45.2 45.2 NUM dpc-459 70 144 % % NOUN dpc-459 70 145 ) ) PUNCT dpc-459 70 146 ulceration ulceration NOUN dpc-459 70 147 ( ( PUNCT dpc-459 70 148 n,% n,% PROPN dpc-459 70 149 ) ) PUNCT dpc-459 70 150 29 29 NUM dpc-459 70 151 ( ( PUNCT dpc-459 70 152 10.2 10.2 NUM dpc-459 70 153 % % NOUN dpc-459 70 154 ) ) PUNCT dpc-459 70 155 2 2 NUM dpc-459 70 156 ( ( PUNCT dpc-459 70 157 6.5 6.5 NUM dpc-459 70 158 % % NOUN dpc-459 70 159 ) ) PUNCT dpc-459 70 160 3 3 NUM dpc-459 70 161 ( ( PUNCT dpc-459 70 162 7.1 7.1 NUM dpc-459 70 163 % % NOUN dpc-459 70 164 ) ) PUNCT dpc-459 70 165 figure figure NOUN dpc-459 70 166 2 2 NUM dpc-459 70 167 . . PUNCT dpc-459 70 168 clinical clinical ADJ dpc-459 70 169 images image NOUN dpc-459 70 170 of of ADP dpc-459 70 171 nevus nevus NOUN dpc-459 70 172 - - PUNCT dpc-459 70 173 associated associate VERB dpc-459 70 174 melanomas melanoma NOUN dpc-459 70 175 . . PUNCT dpc-459 71 1 [ [ X dpc-459 71 2 copyright copyright NOUN dpc-459 71 3 : : PUNCT dpc-459 71 4 © © PROPN dpc-459 71 5 2018 2018 NUM dpc-459 71 6 alendar alendar NOUN dpc-459 71 7 et et PROPN dpc-459 71 8 al al PROPN dpc-459 71 9 . . PROPN dpc-459 71 10 ] ] PUNCT dpc-459 72 1 one one NUM dpc-459 72 2 nevus nevus NOUN dpc-459 72 3 has have VERB dpc-459 72 4 a a DET dpc-459 72 5 pattern pattern NOUN dpc-459 72 6 of of ADP dpc-459 72 7 clods clod NOUN dpc-459 72 8 and and CCONJ dpc-459 72 9 the the DET dpc-459 72 10 other other ADJ dpc-459 72 11 a a DET dpc-459 72 12 reticular reticular ADJ dpc-459 72 13 pattern pattern NOUN dpc-459 72 14 . . PUNCT dpc-459 73 1 discussion discussion NOUN dpc-459 73 2 the the DET dpc-459 73 3 results result NOUN dpc-459 73 4 of of ADP dpc-459 73 5 our our PRON dpc-459 73 6 study study NOUN dpc-459 73 7 support support VERB dpc-459 73 8 the the DET dpc-459 73 9 view view NOUN dpc-459 73 10 that that SCONJ dpc-459 73 11 most most ADJ dpc-459 73 12 melanomas melanomas NOUN dpc-459 73 13 arise arise VERB dpc-459 73 14 de de X dpc-459 73 15 novo novo PROPN dpc-459 73 16 . . PUNCT dpc-459 74 1 the the DET dpc-459 74 2 proportion proportion NOUN dpc-459 74 3 of of ADP dpc-459 74 4 nevus nevus NOUN dpc-459 74 5 - - PUNCT dpc-459 74 6 associated associate VERB dpc-459 74 7 melanomas melanomas NOUN dpc-459 74 8 in in ADP dpc-459 74 9 our our PRON dpc-459 74 10 study study NOUN dpc-459 74 11 was be AUX dpc-459 74 12 smaller small ADJ dpc-459 74 13 than than ADP dpc-459 74 14     SPACE dpc-459 74 15 10 10 NUM dpc-459 74 16 % % NOUN dpc-459 74 17 research research NOUN dpc-459 74 18 | | ADV dpc-459 74 19 dermatol dermatol ADJ dpc-459 74 20 pract pract NOUN dpc-459 74 21 concept concept NOUN dpc-459 74 22 2018;8(2):7 2018;8(2):7 PROPN dpc-459 74 23 107 107 NUM dpc-459 74 24 and and CCONJ dpc-459 74 25 thus thus ADV dpc-459 74 26 lower low ADJ dpc-459 74 27 than than ADP dpc-459 74 28 in in ADP dpc-459 74 29 most most ADJ dpc-459 74 30 other other ADJ dpc-459 74 31 studies study NOUN dpc-459 74 32 on on ADP dpc-459 74 33 this this DET dpc-459 74 34 topic topic NOUN dpc-459 74 35 [ [ X dpc-459 74 36 2 2 NUM dpc-459 74 37 ] ] PUNCT dpc-459 74 38 . . PUNCT dpc-459 75 1 the the DET dpc-459 75 2 reason reason NOUN dpc-459 75 3 for for ADP dpc-459 75 4 this this PRON dpc-459 75 5 might might AUX dpc-459 75 6 be be AUX dpc-459 75 7 that that SCONJ dpc-459 75 8 we we PRON dpc-459 75 9 were be AUX dpc-459 75 10 very very ADV dpc-459 75 11 strict strict ADJ dpc-459 75 12 with with ADP dpc-459 75 13 regard regard NOUN dpc-459 75 14 to to ADP dpc-459 75 15 the the DET dpc-459 75 16 applied apply VERB dpc-459 75 17 histopathologic histopathologic NOUN dpc-459 75 18 criteria criterion NOUN dpc-459 75 19 to to PART dpc-459 75 20 differentiate differentiate VERB dpc-459 75 21 between between ADP dpc-459 75 22 melanocytes melanocyte NOUN dpc-459 75 23 of of ADP dpc-459 75 24 a a DET dpc-459 75 25 nevus nevus NOUN dpc-459 75 26 and and CCONJ dpc-459 75 27 a a DET dpc-459 75 28 melanoma melanoma NOUN dpc-459 75 29 . . PUNCT dpc-459 76 1 this this PRON dpc-459 76 2 resulted result VERB dpc-459 76 3 in in ADP dpc-459 76 4 a a DET dpc-459 76 5 considerable considerable ADJ dpc-459 76 6 proportion proportion NOUN dpc-459 76 7 of of ADP dpc-459 76 8 cases case NOUN dpc-459 76 9 in in ADP dpc-459 76 10 which which PRON dpc-459 76 11 we we PRON dpc-459 76 12 could could AUX dpc-459 76 13 not not PART dpc-459 76 14 decide decide VERB dpc-459 76 15 if if SCONJ dpc-459 76 16 there there PRON dpc-459 76 17 was be VERB dpc-459 76 18 an an DET dpc-459 76 19 associated associated ADJ dpc-459 76 20 nevus nevus NOUN dpc-459 76 21 or or CCONJ dpc-459 76 22 not not PART dpc-459 76 23 . . PUNCT dpc-459 77 1 if if SCONJ dpc-459 77 2 these these DET dpc-459 77 3 cases case NOUN dpc-459 77 4 were be AUX dpc-459 77 5 to to PART dpc-459 77 6 be be AUX dpc-459 77 7 added add VERB dpc-459 77 8 to to ADP dpc-459 77 9 the the DET dpc-459 77 10 obvious obvious ADJ dpc-459 77 11 nevus nevus ADJ dpc-459 77 12 - - PUNCT dpc-459 77 13 associated associate VERB dpc-459 77 14 melanomas melanoma NOUN dpc-459 77 15 , , PUNCT dpc-459 77 16 the the DET dpc-459 77 17 proportion proportion NOUN dpc-459 77 18 of of ADP dpc-459 77 19 nevus nevus NOUN dpc-459 77 20 - - PUNCT dpc-459 77 21 associated associate VERB dpc-459 77 22 melanomas melanomas NOUN dpc-459 77 23 in in ADP dpc-459 77 24 our our PRON dpc-459 77 25 study study NOUN dpc-459 77 26 would would AUX dpc-459 77 27 be be AUX dpc-459 77 28 in in ADP dpc-459 77 29 the the DET dpc-459 77 30 range range NOUN dpc-459 77 31 of of ADP dpc-459 77 32     SPACE dpc-459 77 33 20 20 NUM dpc-459 77 34 % % NOUN dpc-459 77 35 , , PUNCT dpc-459 77 36 which which PRON dpc-459 77 37 is be AUX dpc-459 77 38 similar similar ADJ dpc-459 77 39 to to ADP dpc-459 77 40 most most ADJ dpc-459 77 41 other other ADJ dpc-459 77 42     SPACE dpc-459 77 43 studies study NOUN dpc-459 77 44 . . PUNCT dpc-459 78 1 the the DET dpc-459 78 2 concept concept NOUN dpc-459 78 3 of of ADP dpc-459 78 4 stepwise stepwise ADJ dpc-459 78 5 tumor tumor NOUN dpc-459 78 6 progression progression NOUN dpc-459 78 7 from from ADP dpc-459 78 8 a a DET dpc-459 78 9 common common ADJ dpc-459 78 10 nevus nevus NOUN dpc-459 78 11 over over ADP dpc-459 78 12 a a DET dpc-459 78 13 “ " PUNCT dpc-459 78 14 dysplastic dysplastic ADJ dpc-459 78 15 nevus nevus NOUN dpc-459 78 16 ” " PUNCT dpc-459 78 17 to to ADP dpc-459 78 18 melanoma melanoma VERB dpc-459 78 19 , , PUNCT dpc-459 78 20 as as SCONJ dpc-459 78 21 set set VERB dpc-459 78 22 forth forth ADP dpc-459 78 23 by by ADP dpc-459 78 24 clark clark NOUN dpc-459 78 25 and and CCONJ dpc-459 78 26 others other NOUN dpc-459 78 27 , , PUNCT dpc-459 78 28 is be AUX dpc-459 78 29 not not PART dpc-459 78 30 supported support VERB dpc-459 78 31 by by ADP dpc-459 78 32 our our PRON dpc-459 78 33 data datum NOUN dpc-459 78 34 [ [ X dpc-459 78 35 10 10 NUM dpc-459 78 36 ] ] PUNCT dpc-459 78 37 . . PUNCT dpc-459 79 1 we we PRON dpc-459 79 2 found find VERB dpc-459 79 3 that that SCONJ dpc-459 79 4 if if SCONJ dpc-459 79 5 melanomas melanoma NOUN dpc-459 79 6 develop develop VERB dpc-459 79 7 in in ADP dpc-459 79 8 an an DET dpc-459 79 9 associated associated ADJ dpc-459 79 10 nevus nevus NOUN dpc-459 79 11 , , PUNCT dpc-459 79 12 it it PRON dpc-459 79 13 is be AUX dpc-459 79 14 most most ADV dpc-459 79 15 often often ADV dpc-459 79 16 a a DET dpc-459 79 17 “ " PUNCT dpc-459 79 18 superficial superficial ADJ dpc-459 79 19 ” " PUNCT dpc-459 79 20 or or CCONJ dpc-459 79 21 a a DET dpc-459 79 22 “ " PUNCT dpc-459 79 23 superficial superficial ADJ dpc-459 79 24 and and CCONJ dpc-459 79 25 deep deep ADJ dpc-459 79 26 ” " PUNCT dpc-459 79 27 congenital congenital ADJ dpc-459 79 28 nevus nevu NOUN dpc-459 79 29 . . PUNCT dpc-459 80 1 a a DET dpc-459 80 2 clark clark NOUN dpc-459 80 3 nevus nevus NOUN dpc-459 80 4 is be AUX dpc-459 80 5 less less ADV dpc-459 80 6 often often ADV dpc-459 80 7 associated associate VERB dpc-459 80 8 with with ADP dpc-459 80 9 a a DET dpc-459 80 10 melanoma melanoma NOUN dpc-459 80 11 . . PUNCT dpc-459 81 1 our our PRON dpc-459 81 2 findings finding NOUN dpc-459 81 3 do do AUX dpc-459 81 4 not not PART dpc-459 81 5 support support VERB dpc-459 81 6 the the DET dpc-459 81 7 concept concept NOUN dpc-459 81 8 that that SCONJ dpc-459 81 9 “ " PUNCT dpc-459 81 10 melanocytic melanocytic ADJ dpc-459 81 11 dysplasia dysplasia NOUN dpc-459 81 12 , , PUNCT dpc-459 81 13 ” " PUNCT dpc-459 81 14 if if SCONJ dpc-459 81 15 it it PRON dpc-459 81 16 exists exist VERB dpc-459 81 17 , , PUNCT dpc-459 81 18 has have VERB dpc-459 81 19 any any DET dpc-459 81 20 predictive predictive ADJ dpc-459 81 21 value value NOUN dpc-459 81 22 with with ADP dpc-459 81 23 regard regard NOUN dpc-459 81 24 to to ADP dpc-459 81 25 the the DET dpc-459 81 26 chance chance NOUN dpc-459 81 27 that that SCONJ dpc-459 81 28 a a DET dpc-459 81 29 melanoma melanoma NOUN dpc-459 81 30 may may AUX dpc-459 81 31 arise arise VERB dpc-459 81 32 in in ADP dpc-459 81 33 a a DET dpc-459 81 34 specific specific ADJ dpc-459 81 35 nevus nevus NOUN dpc-459 81 36 . . PUNCT dpc-459 82 1 given give VERB dpc-459 82 2 the the DET dpc-459 82 3 original original ADJ dpc-459 82 4 description description NOUN dpc-459 82 5 by by ADP dpc-459 82 6 clark clark NOUN dpc-459 82 7 and and CCONJ dpc-459 82 8 coworkers coworker NOUN dpc-459 82 9 , , PUNCT dpc-459 82 10 it it PRON dpc-459 82 11 has have AUX dpc-459 82 12 been be AUX dpc-459 82 13 proposed propose VERB dpc-459 82 14 that that SCONJ dpc-459 82 15 the the DET dpc-459 82 16 “ " PUNCT dpc-459 82 17 dysplastic dysplastic ADJ dpc-459 82 18 nevus nevus NOUN dpc-459 82 19 ” " PUNCT dpc-459 82 20 is be AUX dpc-459 82 21 a a DET dpc-459 82 22 risk risk NOUN dpc-459 82 23 marker marker NOUN dpc-459 82 24 and and CCONJ dpc-459 82 25 a a DET dpc-459 82 26 precursor precursor NOUN dpc-459 82 27 of of ADP dpc-459 82 28 melanoma[11 melanoma[11 NOUN dpc-459 82 29 ] ] PUNCT dpc-459 82 30 . . PUNCT dpc-459 83 1 recently recently ADV dpc-459 83 2 the the DET dpc-459 83 3 latter latter ADJ dpc-459 83 4 view view NOUN dpc-459 83 5 has have AUX dpc-459 83 6 been be AUX dpc-459 83 7 questioned question VERB dpc-459 83 8 because because SCONJ dpc-459 83 9 clinical clinical ADJ dpc-459 83 10 data datum NOUN dpc-459 83 11 have have AUX dpc-459 83 12 shown show VERB dpc-459 83 13 that that SCONJ dpc-459 83 14 it it PRON dpc-459 83 15 lacks lack VERB dpc-459 83 16 legitimacy legitimacy NOUN dpc-459 83 17 . . PUNCT dpc-459 84 1 the the DET dpc-459 84 2 subject subject NOUN dpc-459 84 3 of of ADP dpc-459 84 4 the the DET dpc-459 84 5 “ " PUNCT dpc-459 84 6 dysplastic dysplastic ADJ dpc-459 84 7 nevus nevus NOUN dpc-459 84 8 ” " PUNCT dpc-459 84 9 and and CCONJ dpc-459 84 10 its its PRON dpc-459 84 11 role role NOUN dpc-459 84 12 as as ADP dpc-459 84 13 a a DET dpc-459 84 14 precursor precursor NOUN dpc-459 84 15 of of ADP dpc-459 84 16 melanoma melanoma NOUN dpc-459 84 17 is be AUX dpc-459 84 18 difficult difficult ADJ dpc-459 84 19 to to PART dpc-459 84 20 comprehend comprehend VERB dpc-459 84 21 because because SCONJ dpc-459 84 22 what what PRON dpc-459 84 23 is be AUX dpc-459 84 24 usually usually ADV dpc-459 84 25 termed term VERB dpc-459 84 26 “ " PUNCT dpc-459 84 27 dysplastic dysplastic ADJ dpc-459 84 28 nevus nevus NOUN dpc-459 84 29 ” " PUNCT dpc-459 84 30 is be AUX dpc-459 84 31 a a DET dpc-459 84 32 heterogeneous heterogeneous ADJ dpc-459 84 33 group group NOUN dpc-459 84 34 of of ADP dpc-459 84 35 melanocytic melanocytic ADJ dpc-459 84 36 proliferations proliferation NOUN dpc-459 84 37 . . PUNCT dpc-459 85 1 according accord VERB dpc-459 85 2 to to ADP dpc-459 85 3 ackerman ackerman PROPN dpc-459 85 4 , , PUNCT dpc-459 85 5 what what PRON dpc-459 85 6 is be AUX dpc-459 85 7 termed term VERB dpc-459 85 8 “ " PUNCT dpc-459 85 9 dysplastic dysplastic ADJ dpc-459 85 10 nevi nevi ADJ dpc-459 85 11 ” " PUNCT dpc-459 85 12 consist consist NOUN dpc-459 85 13 of of ADP dpc-459 85 14 three three NUM dpc-459 85 15 figure figure NOUN dpc-459 85 16 3 3 NUM dpc-459 85 17 . . PUNCT dpc-459 86 1 clinical clinical ADJ dpc-459 86 2 - - PUNCT dpc-459 86 3 dermatoscopic dermatoscopic NOUN dpc-459 86 4 - - PUNCT dpc-459 86 5 pathologic pathologic ADJ dpc-459 86 6 correlation correlation NOUN dpc-459 86 7 of of ADP dpc-459 86 8 a a DET dpc-459 86 9 melanoma melanoma NOUN dpc-459 86 10 - - PUNCT dpc-459 86 11 associated associate VERB dpc-459 86 12 nevus nevus NOUN dpc-459 86 13 . . PUNCT dpc-459 87 1 [ [ X dpc-459 87 2 copyright copyright NOUN dpc-459 87 3 : : PUNCT dpc-459 87 4 © © PROPN dpc-459 87 5 2018 2018 NUM dpc-459 87 6 alendar alendar NOUN dpc-459 87 7 et et PROPN dpc-459 87 8 al al PROPN dpc-459 87 9 . . PROPN dpc-459 87 10 ] ] PUNCT dpc-459 87 11 figure figure NOUN dpc-459 87 12 4 4 NUM dpc-459 87 13 . . PUNCT dpc-459 88 1 clinical clinical ADJ dpc-459 88 2 - - PUNCT dpc-459 88 3 dermatoscopic dermatoscopic NOUN dpc-459 88 4 - - PUNCT dpc-459 88 5 pathologic pathologic ADJ dpc-459 88 6 correlation correlation NOUN dpc-459 88 7 of of ADP dpc-459 88 8 a a DET dpc-459 88 9 melanoma melanoma NOUN dpc-459 88 10 - - PUNCT dpc-459 88 11 associated associate VERB dpc-459 88 12 nevus nevus NOUN dpc-459 88 13 . . PUNCT dpc-459 89 1 [ [ X dpc-459 89 2 copyright copyright NOUN dpc-459 89 3 : : PUNCT dpc-459 89 4 © © PROPN dpc-459 89 5 2018 2018 NUM dpc-459 89 6 alendar alendar NOUN dpc-459 89 7 et et PROPN dpc-459 89 8 al al PROPN dpc-459 89 9 . . PROPN dpc-459 89 10 ] ] PUNCT dpc-459 90 1 108 108 NUM dpc-459 90 2 research research NOUN dpc-459 90 3 | | ADV dpc-459 90 4 dermatol dermatol NOUN dpc-459 90 5 pract pract NOUN dpc-459 90 6 concept concept NOUN dpc-459 90 7 2018;8(2):7 2018;8(2):7 NOUN dpc-459 90 8 tal tal X dpc-459 90 9 nevi nevi X dpc-459 90 10 are be AUX dpc-459 90 11 most most ADV dpc-459 90 12 commonly commonly ADV dpc-459 90 13 associated associate VERB dpc-459 90 14 with with ADP dpc-459 90 15 melanoma melanoma NOUN dpc-459 90 16 , , PUNCT dpc-459 90 17 we we PRON dpc-459 90 18 do do AUX dpc-459 90 19 not not PART dpc-459 90 20 think think VERB dpc-459 90 21 that that SCONJ dpc-459 90 22 this this PRON dpc-459 90 23 supports support VERB dpc-459 90 24 the the DET dpc-459 90 25 view view NOUN dpc-459 90 26 that that SCONJ dpc-459 90 27 they they PRON dpc-459 90 28 should should AUX dpc-459 90 29 be be AUX dpc-459 90 30 excised excise VERB dpc-459 90 31 prophylactically prophylactically ADV dpc-459 90 32 to to PART dpc-459 90 33 prevent prevent VERB dpc-459 90 34 melanoma melanoma NOUN dpc-459 90 35 . . PUNCT dpc-459 91 1 the the DET dpc-459 91 2 risk risk NOUN dpc-459 91 3 of of ADP dpc-459 91 4 malignant malignant ADJ dpc-459 91 5 transformation transformation NOUN dpc-459 91 6 of of ADP dpc-459 91 7 a a DET dpc-459 91 8 single single ADJ dpc-459 91 9 nevus nevus NOUN dpc-459 91 10 is be AUX dpc-459 91 11 so so ADV dpc-459 91 12 low low ADJ dpc-459 91 13 that that SCONJ dpc-459 91 14 a a DET dpc-459 91 15 general general ADJ dpc-459 91 16 recommendation recommendation NOUN dpc-459 91 17 for for ADP dpc-459 91 18 prophylactic prophylactic ADJ dpc-459 91 19 excision excision NOUN dpc-459 91 20 can can AUX dpc-459 91 21 not not PART dpc-459 91 22 be be AUX dpc-459 91 23 given give VERB dpc-459 91 24 . . PUNCT dpc-459 92 1 it it PRON dpc-459 92 2 is be AUX dpc-459 92 3 important important ADJ dpc-459 92 4 to to PART dpc-459 92 5 note note VERB dpc-459 92 6 , , PUNCT dpc-459 92 7 however however ADV dpc-459 92 8 , , PUNCT dpc-459 92 9 that that SCONJ dpc-459 92 10 we we PRON dpc-459 92 11 used use VERB dpc-459 92 12 the the DET dpc-459 92 13 term term NOUN dpc-459 92 14 “ " PUNCT dpc-459 92 15 congenital congenital ADJ dpc-459 92 16 ” " PUNCT dpc-459 92 17 in in ADP dpc-459 92 18 a a DET dpc-459 92 19 histopathologic histopathologic ADJ dpc-459 92 20 sense sense NOUN dpc-459 92 21 . . PUNCT dpc-459 93 1 it it PRON dpc-459 93 2 does do AUX dpc-459 93 3 not not PART dpc-459 93 4 mean mean VERB dpc-459 93 5 that that SCONJ dpc-459 93 6 those those DET dpc-459 93 7 nevi nevi NOUN dpc-459 93 8 are be AUX dpc-459 93 9 present present ADJ dpc-459 93 10 at at ADP dpc-459 93 11 birth birth NOUN dpc-459 93 12 . . PUNCT dpc-459 94 1 “ " PUNCT dpc-459 94 2 superficial superficial ADJ dpc-459 94 3 ” " PUNCT dpc-459 94 4 and and CCONJ dpc-459 94 5 “ " PUNCT dpc-459 94 6 superficial superficial ADJ dpc-459 94 7 and and CCONJ dpc-459 94 8 deep deep ADJ dpc-459 94 9 ” " PUNCT dpc-459 94 10 congenital congenital ADJ dpc-459 94 11 nevi nevi NOUN dpc-459 94 12 usually usually ADV dpc-459 94 13 appear appear VERB dpc-459 94 14 in in ADP dpc-459 94 15 childhood childhood NOUN dpc-459 94 16 or or CCONJ dpc-459 94 17 adolescence adolescence NOUN dpc-459 94 18 but but CCONJ dpc-459 94 19 share share VERB dpc-459 94 20 histomorphologic histomorphologic ADJ dpc-459 94 21 features feature NOUN dpc-459 94 22 ( ( PUNCT dpc-459 94 23 architecture architecture NOUN dpc-459 94 24 , , PUNCT dpc-459 94 25 adnexocentricity adnexocentricity NOUN dpc-459 94 26 ) ) PUNCT dpc-459 94 27 with with ADP dpc-459 94 28 large large ADJ dpc-459 94 29 congenital congenital ADJ dpc-459 94 30 nevi nevi NOUN dpc-459 94 31 . . PUNCT dpc-459 95 1 to to PART dpc-459 95 2 answer answer VERB dpc-459 95 3 the the DET dpc-459 95 4 question question NOUN dpc-459 95 5 as as ADP dpc-459 95 6 to to ADP dpc-459 95 7 whether whether SCONJ dpc-459 95 8 prophylactic prophylactic ADJ dpc-459 95 9 excisions excision NOUN dpc-459 95 10 of of ADP dpc-459 95 11 small small ADJ dpc-459 95 12 congenital congenital ADJ dpc-459 95 13 nevi nevi NOUN dpc-459 95 14 are be AUX dpc-459 95 15 worthwhile worthwhile ADJ dpc-459 95 16 , , PUNCT dpc-459 95 17 we we PRON dpc-459 95 18 would would AUX dpc-459 95 19 need need VERB dpc-459 95 20 a a DET dpc-459 95 21 prospective prospective ADJ dpc-459 95 22 interventional interventional ADJ dpc-459 95 23 study study NOUN dpc-459 95 24 , , PUNCT dpc-459 95 25 but but CCONJ dpc-459 95 26 the the DET dpc-459 95 27 low low ADJ dpc-459 95 28 incidence incidence NOUN dpc-459 95 29 of of ADP dpc-459 95 30 melanoma melanoma NOUN dpc-459 95 31 in in ADP dpc-459 95 32 comparison comparison NOUN dpc-459 95 33 to to ADP dpc-459 95 34 the the DET dpc-459 95 35 high high ADJ dpc-459 95 36 number number NOUN dpc-459 95 37 of of ADP dpc-459 95 38 nevi nevi ADJ dpc-459 95 39 make make VERB dpc-459 95 40 it it PRON dpc-459 95 41 highly highly ADV dpc-459 95 42 unlikely unlikely ADJ dpc-459 95 43 that that SCONJ dpc-459 95 44 such such DET dpc-459 95 45 a a DET dpc-459 95 46 prospective prospective ADJ dpc-459 95 47 interventional interventional ADJ dpc-459 95 48 trial trial NOUN dpc-459 95 49 will will AUX dpc-459 95 50 ever ever ADV dpc-459 95 51 be be AUX dpc-459 95 52 conducted conduct VERB dpc-459 95 53 . . PUNCT dpc-459 96 1 different different ADJ dpc-459 96 2 types type NOUN dpc-459 96 3 of of ADP dpc-459 96 4 nevi nevi NOUN dpc-459 96 5 : : PUNCT dpc-459 96 6 ( ( PUNCT dpc-459 96 7 1 1 X dpc-459 96 8 ) ) PUNCT dpc-459 96 9 clark clark NOUN dpc-459 96 10 nevi nevi PROPN dpc-459 96 11 , , PUNCT dpc-459 96 12 ( ( PUNCT dpc-459 96 13 2 2 X dpc-459 96 14 ) ) PUNCT dpc-459 96 15 “ " PUNCT dpc-459 96 16 superficial”congenital superficial”congenital PROPN dpc-459 96 17 nevi nevi X dpc-459 96 18 , , PUNCT dpc-459 96 19 and and CCONJ dpc-459 96 20 ( ( PUNCT dpc-459 96 21 3 3 X dpc-459 96 22 ) ) PUNCT dpc-459 96 23 “ " PUNCT dpc-459 96 24 superficial superficial ADJ dpc-459 96 25 and and CCONJ dpc-459 96 26 deep deep ADJ dpc-459 96 27 ” " PUNCT dpc-459 96 28 congenital congenital ADJ dpc-459 96 29 nevi nevi NOUN dpc-459 96 30 . . PUNCT dpc-459 97 1 clark clark PROPN dpc-459 97 2 nevi nevi PROPN dpc-459 97 3 are be AUX dpc-459 97 4 clinically clinically ADV dpc-459 97 5 flat flat ADJ dpc-459 97 6 and and CCONJ dpc-459 97 7 mainly mainly ADV dpc-459 97 8 junctional junctional ADJ dpc-459 97 9 , , PUNCT dpc-459 97 10 although although SCONJ dpc-459 97 11 a a DET dpc-459 97 12 few few ADJ dpc-459 97 13 nests nest NOUN dpc-459 97 14 of of ADP dpc-459 97 15 melanocytes melanocyte NOUN dpc-459 97 16 may may AUX dpc-459 97 17 be be AUX dpc-459 97 18 present present ADJ dpc-459 97 19 in in ADP dpc-459 97 20 the the DET dpc-459 97 21 papillary papillary ADJ dpc-459 97 22 dermis dermis NOUN dpc-459 97 23 . . PUNCT dpc-459 98 1 dermatoscopically dermatoscopically ADV dpc-459 98 2 they they PRON dpc-459 98 3 usually usually ADV dpc-459 98 4 show show VERB dpc-459 98 5 a a DET dpc-459 98 6 reticular reticular ADJ dpc-459 98 7 pattern pattern NOUN dpc-459 98 8 . . PUNCT dpc-459 99 1 “ " PUNCT dpc-459 99 2 superficial superficial ADJ dpc-459 99 3 ” " PUNCT dpc-459 99 4 and and CCONJ dpc-459 99 5 “ " PUNCT dpc-459 99 6 superficial superficial ADJ dpc-459 99 7 and and CCONJ dpc-459 99 8 deep deep ADJ dpc-459 99 9 ” " PUNCT dpc-459 99 10 congenital congenital ADJ dpc-459 99 11 nevi nevi NOUN dpc-459 99 12 usually usually ADV dpc-459 99 13 have have VERB dpc-459 99 14 a a DET dpc-459 99 15 junctional junctional ADJ dpc-459 99 16 part part NOUN dpc-459 99 17 but but CCONJ dpc-459 99 18 a a DET dpc-459 99 19 more more ADV dpc-459 99 20 prominent prominent ADJ dpc-459 99 21 dermal dermal NOUN dpc-459 99 22 part part NOUN dpc-459 99 23 . . PUNCT dpc-459 100 1 while while SCONJ dpc-459 100 2 melanocytes melanocyte NOUN dpc-459 100 3 in in ADP dpc-459 100 4 a a DET dpc-459 100 5 “ " PUNCT dpc-459 100 6 superficial superficial ADJ dpc-459 100 7 ” " PUNCT dpc-459 100 8 congenital congenital ADJ dpc-459 100 9 nevus nevus NOUN dpc-459 100 10 are be AUX dpc-459 100 11 confined confine VERB dpc-459 100 12 to to ADP dpc-459 100 13 the the DET dpc-459 100 14 papillary papillary ADJ dpc-459 100 15 dermis dermis NOUN dpc-459 100 16 and and CCONJ dpc-459 100 17 the the DET dpc-459 100 18 upper upper ADJ dpc-459 100 19 part part NOUN dpc-459 100 20 of of ADP dpc-459 100 21 the the DET dpc-459 100 22 reticular reticular ADJ dpc-459 100 23 dermis dermis NOUN dpc-459 100 24 they they PRON dpc-459 100 25 extend extend VERB dpc-459 100 26 to to ADP dpc-459 100 27 the the DET dpc-459 100 28 deep deep ADJ dpc-459 100 29 reticular reticular ADJ dpc-459 100 30 dermis dermis NOUN dpc-459 100 31 in in ADP dpc-459 100 32 a a DET dpc-459 100 33 “ " PUNCT dpc-459 100 34 superficial superficial ADJ dpc-459 100 35 and and CCONJ dpc-459 100 36 deep deep ADJ dpc-459 100 37 ” " PUNCT dpc-459 100 38 congenital congenital ADJ dpc-459 100 39 nevus nevu NOUN dpc-459 100 40 . . PUNCT dpc-459 101 1 both both DET dpc-459 101 2 nevi nevus NOUN dpc-459 101 3 are be AUX dpc-459 101 4 usually usually ADV dpc-459 101 5 raised raise VERB dpc-459 101 6 clinically clinically ADV dpc-459 101 7 . . PUNCT dpc-459 102 1 dermatoscopically dermatoscopically ADV dpc-459 102 2 they they PRON dpc-459 102 3 may may AUX dpc-459 102 4 show show VERB dpc-459 102 5 a a DET dpc-459 102 6 pattern pattern NOUN dpc-459 102 7 of of ADP dpc-459 102 8 clods clod NOUN dpc-459 102 9 , , PUNCT dpc-459 102 10 a a DET dpc-459 102 11 reticular reticular ADJ dpc-459 102 12 pattern pattern NOUN dpc-459 102 13 , , PUNCT dpc-459 102 14 or or CCONJ dpc-459 102 15 a a DET dpc-459 102 16 combination combination NOUN dpc-459 102 17 of of ADP dpc-459 102 18 both both PRON dpc-459 102 19 . . PUNCT dpc-459 103 1 if if SCONJ dpc-459 103 2 clinical clinical ADJ dpc-459 103 3 and and CCONJ dpc-459 103 4 dermatoscopic dermatoscopic ADJ dpc-459 103 5 images image NOUN dpc-459 103 6 of of ADP dpc-459 103 7 these these DET dpc-459 103 8 nevi nevi NOUN dpc-459 103 9 were be AUX dpc-459 103 10 available available ADJ dpc-459 103 11 in in ADP dpc-459 103 12 our our PRON dpc-459 103 13 series series NOUN dpc-459 103 14 , , PUNCT dpc-459 103 15 they they PRON dpc-459 103 16 looked look VERB dpc-459 103 17 rather rather ADV dpc-459 103 18 inconspicuous inconspicuous ADJ dpc-459 103 19 and and CCONJ dpc-459 103 20 not not PART dpc-459 103 21 atypical atypical ADJ dpc-459 103 22 or or CCONJ dpc-459 103 23 “ " PUNCT dpc-459 103 24 dysplastic dysplastic ADJ dpc-459 103 25 . . PUNCT dpc-459 103 26 ” " PUNCT dpc-459 104 1 although although SCONJ dpc-459 104 2 our our PRON dpc-459 104 3 study study NOUN dpc-459 104 4 shows show VERB dpc-459 104 5 that that SCONJ dpc-459 104 6 small small ADJ dpc-459 104 7 congenifigure congenifigure NOUN dpc-459 104 8 5 5 NUM dpc-459 104 9 . . NOUN dpc-459 104 10 clinical clinical ADJ dpc-459 104 11 and and CCONJ dpc-459 104 12 dermatoscopic dermatoscopic ADJ dpc-459 104 13 images image NOUN dpc-459 104 14 of of ADP dpc-459 104 15 two two NUM dpc-459 104 16 nevus nevus ADJ dpc-459 104 17 - - PUNCT dpc-459 104 18 associated associate VERB dpc-459 104 19 melanomas melanoma NOUN dpc-459 104 20 . . PUNCT dpc-459 105 1 [ [ X dpc-459 105 2 copyright copyright NOUN dpc-459 105 3 : : PUNCT dpc-459 105 4 © © PROPN dpc-459 105 5 2018 2018 NUM dpc-459 105 6 alendar alendar NOUN dpc-459 105 7 et et PROPN dpc-459 105 8 al al PROPN dpc-459 105 9 . . PROPN dpc-459 105 10 ] ] PUNCT dpc-459 106 1 references reference NOUN dpc-459 106 2 1 1 NUM dpc-459 106 3 . . PUNCT dpc-459 106 4 bevona bevona PROPN dpc-459 106 5 c c PROPN dpc-459 106 6 , , PUNCT dpc-459 106 7 goggins goggins PROPN dpc-459 106 8 w w PROPN dpc-459 106 9 , , PUNCT dpc-459 106 10 quinn quinn PROPN dpc-459 106 11 t t PROPN dpc-459 106 12 , , PUNCT dpc-459 106 13 et et PROPN dpc-459 106 14     SPACE dpc-459 106 15 al al PROPN dpc-459 106 16 . . PROPN dpc-459 107 1 cutaneous cutaneous ADJ dpc-459 107 2 melanomas melanoma NOUN dpc-459 107 3 associated associate VERB dpc-459 107 4 with with ADP dpc-459 107 5 nevi nevi PROPN dpc-459 107 6 . . PUNCT dpc-459 108 1 arch arch ADJ dpc-459 108 2 dermatol dermatol NOUN dpc-459 108 3 . . PUNCT dpc-459 109 1 2003;139:1620 2003;139:1620 NUM dpc-459 109 2 - - SYM dpc-459 109 3 1624 1624 NUM dpc-459 109 4 . . PUNCT dpc-459 110 1 2 2 X dpc-459 110 2 . . NOUN dpc-459 110 3 pampena pampena NOUN dpc-459 110 4 r r NOUN dpc-459 110 5 , , PUNCT dpc-459 110 6 kyrgidis kyrgidi NOUN dpc-459 110 7 a a PRON dpc-459 110 8 , , PUNCT dpc-459 110 9 lallas lallas PROPN dpc-459 110 10 a a PRON dpc-459 110 11 , , PUNCT dpc-459 110 12 moscarella moscarella NOUN dpc-459 110 13 e e NOUN dpc-459 110 14 , , PUNCT dpc-459 110 15 argenziano argenziano ADJ dpc-459 110 16 g g NOUN dpc-459 110 17 , , PUNCT dpc-459 110 18 longo longo PROPN dpc-459 110 19 c. c. PROPN dpc-459 110 20 a a DET dpc-459 110 21 meta meta ADJ dpc-459 110 22 - - PUNCT dpc-459 110 23 analysis analysis NOUN dpc-459 110 24 of of ADP dpc-459 110 25 nevus nevus NOUN dpc-459 110 26 - - PUNCT dpc-459 110 27 associated associate VERB dpc-459 110 28 melanoma melanoma NOUN dpc-459 110 29 : : PUNCT dpc-459 110 30 prevalence prevalence NOUN dpc-459 110 31 and and CCONJ dpc-459 110 32 practical practical ADJ dpc-459 110 33 implications implication NOUN dpc-459 110 34 . . PUNCT dpc-459 111 1 j j PROPN dpc-459 111 2 am be AUX dpc-459 111 3 acad acad ADJ dpc-459 111 4 dermatol dermatol NOUN dpc-459 111 5 . . PUNCT dpc-459 112 1 2017 2017 NUM dpc-459 112 2     SPACE dpc-459 112 3 nov;77(5):938 nov;77(5):938 PROPN dpc-459 112 4 - - PUNCT dpc-459 112 5 945.e4 945.e4 NUM dpc-459 112 6 . . PUNCT dpc-459 113 1 3 3 X dpc-459 113 2 . . X dpc-459 113 3 kaddu kaddu PROPN dpc-459 113 4 s s PROPN dpc-459 113 5 , , PUNCT dpc-459 113 6 smolle smolle PROPN dpc-459 113 7 j j PROPN dpc-459 113 8 , , PUNCT dpc-459 113 9 zenahlik zenahlik PROPN dpc-459 113 10 p p X dpc-459 113 11 , , PUNCT dpc-459 113 12 et et PROPN dpc-459 113 13     SPACE dpc-459 113 14 al al PROPN dpc-459 113 15 . . PROPN dpc-459 113 16 melanoma melanoma PROPN dpc-459 113 17 with with ADP dpc-459 113 18 benign benign ADJ dpc-459 113 19 melanocytic melanocytic ADJ dpc-459 113 20 naevus naevus NOUN dpc-459 113 21 components component NOUN dpc-459 113 22 : : PUNCT dpc-459 113 23 reappraisal reappraisal NOUN dpc-459 113 24 of of ADP dpc-459 113 25 clinicopathological clinicopathological ADJ dpc-459 113 26 features feature NOUN dpc-459 113 27 and and CCONJ dpc-459 113 28 prognosis prognosis NOUN dpc-459 113 29 . . PUNCT dpc-459 114 1 melanoma melanoma NOUN dpc-459 114 2 res re NOUN dpc-459 114 3 . . PUNCT dpc-459 115 1 2002;12:271 2002;12:271 NOUN dpc-459 115 2 - - SYM dpc-459 115 3 278 278 NUM dpc-459 115 4 . . PUNCT dpc-459 116 1 4 4 NUM dpc-459 116 2 . . X dpc-459 116 3 banky banky PROPN dpc-459 116 4 j j PROPN dpc-459 116 5 , , PUNCT dpc-459 116 6 kelly kelly PROPN dpc-459 116 7 jw jw PROPN dpc-459 116 8 , , PUNCT dpc-459 116 9 english english PROPN dpc-459 116 10 dr dr PROPN dpc-459 116 11 , , PUNCT dpc-459 116 12 et et PROPN dpc-459 116 13     SPACE dpc-459 116 14 al al PROPN dpc-459 116 15 . . PROPN dpc-459 116 16 incidence incidence NOUN dpc-459 116 17 of of ADP dpc-459 116 18 new new ADJ dpc-459 116 19 and and CCONJ dpc-459 116 20 changed change VERB dpc-459 116 21 nevi nevi ADJ dpc-459 116 22 and and CCONJ dpc-459 116 23 melanomas melanomas PROPN dpc-459 116 24 detected detect VERB dpc-459 116 25 using use VERB dpc-459 116 26 baseline baseline NOUN dpc-459 116 27 images image NOUN dpc-459 116 28 and and CCONJ dpc-459 116 29 dermoscopy dermoscopy VERB dpc-459 116 30 in in ADP dpc-459 116 31 patients patient NOUN dpc-459 116 32 at at ADP dpc-459 116 33 high high ADJ dpc-459 116 34 risk risk NOUN dpc-459 116 35 for for ADP dpc-459 116 36 melanoma melanoma NOUN dpc-459 116 37 . . PUNCT dpc-459 117 1 arch arch ADJ dpc-459 117 2 dermatol dermatol NOUN dpc-459 117 3 . . PUNCT dpc-459 118 1 2005;141:998 2005;141:998 NUM dpc-459 118 2 - - SYM dpc-459 118 3 1006 1006 NUM dpc-459 118 4 . . PUNCT dpc-459 119 1 5 5 X dpc-459 119 2 . . X dpc-459 119 3 tsao tsao PROPN dpc-459 119 4 h h PROPN dpc-459 119 5 , , PUNCT dpc-459 119 6 bevona bevona PROPN dpc-459 119 7 c c PROPN dpc-459 119 8 , , PUNCT dpc-459 119 9 goggins goggins PROPN dpc-459 119 10 w w PROPN dpc-459 119 11 , , PUNCT dpc-459 119 12 et et PROPN dpc-459 119 13     SPACE dpc-459 119 14 al al PROPN dpc-459 119 15 . . PUNCT dpc-459 120 1 the the DET dpc-459 120 2 transformation transformation NOUN dpc-459 120 3 rate rate NOUN dpc-459 120 4 of of ADP dpc-459 120 5 moles mole NOUN dpc-459 120 6 ( ( PUNCT dpc-459 120 7 melanocytic melanocytic ADJ dpc-459 120 8 nevi nevi NOUN dpc-459 120 9 ) ) PUNCT dpc-459 120 10 into into ADP dpc-459 120 11 cutaneous cutaneous ADJ dpc-459 120 12 melanoma melanoma NOUN dpc-459 120 13 . . PUNCT dpc-459 121 1 arch arch ADJ dpc-459 121 2 dermatol dermatol NOUN dpc-459 121 3 . . PUNCT dpc-459 122 1 2003;139:282 2003;139:282 NUM dpc-459 122 2 - - SYM dpc-459 122 3 288 288 NUM dpc-459 122 4 . . PUNCT dpc-459 123 1 6 6 NUM dpc-459 123 2 . . X dpc-459 123 3 crowson crowson PROPN dpc-459 123 4 an an PROPN dpc-459 123 5 , , PUNCT dpc-459 123 6 magro magro NOUN dpc-459 123 7 cm cm PROPN dpc-459 123 8 , , PUNCT dpc-459 123 9 sanchez sanchez NOUN dpc-459 123 10 - - PUNCT dpc-459 123 11 carpintero carpintero PROPN dpc-459 124 1 i i PROPN dpc-459 124 2 , , PUNCT dpc-459 124 3 mihm mihm PROPN dpc-459 124 4 mc mc PROPN dpc-459 124 5 jr jr PROPN dpc-459 124 6 . . PUNCT dpc-459 125 1 the the DET dpc-459 125 2 precursors precursor NOUN dpc-459 125 3 of of ADP dpc-459 125 4 malignant malignant ADJ dpc-459 125 5 melanoma melanoma NOUN dpc-459 125 6 . . PUNCT dpc-459 126 1 recent recent ADJ dpc-459 126 2 results result NOUN dpc-459 126 3 cancer cancer NOUN dpc-459 126 4 res re NOUN dpc-459 126 5 . . PUNCT dpc-459 127 1 2002;160:75 2002;160:75 NUM dpc-459 127 2 - - SYM dpc-459 127 3 84 84 NUM dpc-459 127 4 . . PUNCT dpc-459 128 1 7 7 X dpc-459 128 2 . . X dpc-459 128 3 gruber gruber PROPN dpc-459 128 4 sb sb PROPN dpc-459 128 5 , , PUNCT dpc-459 128 6 barnhill barnhill PROPN dpc-459 128 7 rl rl PROPN dpc-459 128 8 , , PUNCT dpc-459 128 9 stenn stenn PROPN dpc-459 128 10 ks ks PROPN dpc-459 128 11 , , PUNCT dpc-459 128 12 et et PROPN dpc-459 128 13 al al PROPN dpc-459 128 14 . . PUNCT dpc-459 128 15 nevomelanocytic nevomelanocytic ADJ dpc-459 128 16 proliferations proliferation NOUN dpc-459 128 17 in in ADP dpc-459 128 18 association association NOUN dpc-459 128 19 with with ADP dpc-459 128 20 cutaneous cutaneous ADJ dpc-459 128 21 malignant malignant ADJ dpc-459 128 22 melanoma melanoma NOUN dpc-459 128 23 : : PUNCT dpc-459 128 24 a a DET dpc-459 128 25 multivariate multivariate NOUN dpc-459 128 26 analysis analysis NOUN dpc-459 128 27 . . PUNCT dpc-459 129 1 j j PROPN dpc-459 129 2 am be AUX dpc-459 129 3 acad acad ADJ dpc-459 129 4 dermatol dermatol NOUN dpc-459 129 5 . . PUNCT dpc-459 130 1 1989;21:773 1989;21:773 NUM dpc-459 130 2 . . PUNCT dpc-459 131 1 8 8 NUM dpc-459 131 2 . . X dpc-459 131 3 kanzler kanzler PROPN dpc-459 131 4 mh mh PROPN dpc-459 131 5 , , PUNCT dpc-459 131 6 mraz mraz PROPN dpc-459 131 7 - - PUNCT dpc-459 131 8 gernhard gernhard PROPN dpc-459 131 9 s. s. PROPN dpc-459 131 10 primary primary ADJ dpc-459 131 11 cutaneous cutaneous ADJ dpc-459 131 12 malignant malignant ADJ dpc-459 131 13 melanoma melanoma NOUN dpc-459 131 14 and and CCONJ dpc-459 131 15 its its PRON dpc-459 131 16 precursor precursor NOUN dpc-459 131 17 lesions lesion NOUN dpc-459 131 18 : : PUNCT dpc-459 131 19 diagnostic diagnostic ADJ dpc-459 131 20 and and CCONJ dpc-459 131 21 therapeutic therapeutic ADJ dpc-459 131 22 overview overview NOUN dpc-459 131 23 . . PUNCT dpc-459 132 1 j j PROPN dpc-459 132 2 am be AUX dpc-459 132 3 acad acad ADJ dpc-459 132 4 dermatol dermatol NOUN dpc-459 132 5 . . PUNCT dpc-459 133 1 2001 2001 NUM dpc-459 133 2 aug;45(2):260 aug;45(2):260 NOUN dpc-459 133 3 - - SYM dpc-459 133 4 276 276 NUM dpc-459 133 5 . . PUNCT dpc-459 134 1 9 9 NUM dpc-459 134 2 . . X dpc-459 134 3 ackerman ackerman PROPN dpc-459 134 4 ab ab PROPN dpc-459 134 5 , , PUNCT dpc-459 134 6 milde milde PROPN dpc-459 134 7 p. p. PROPN dpc-459 134 8 naming naming NOUN dpc-459 134 9 acquired acquire VERB dpc-459 134 10 melanocytic melanocytic ADJ dpc-459 134 11 nevi nevi NOUN dpc-459 134 12 . . PUNCT dpc-459 135 1 common common ADJ dpc-459 135 2 and and CCONJ dpc-459 135 3 dysplastic dysplastic ADJ dpc-459 135 4 , , PUNCT dpc-459 135 5 normal normal ADJ dpc-459 135 6 and and CCONJ dpc-459 135 7 atypical atypical ADJ dpc-459 135 8 , , PUNCT dpc-459 135 9 or or CCONJ dpc-459 135 10 unna unna NOUN dpc-459 135 11 , , PUNCT dpc-459 135 12 miescher miescher NOUN dpc-459 135 13 , , PUNCT dpc-459 135 14 spitz spitz PROPN dpc-459 135 15 , , PUNCT dpc-459 135 16 and and CCONJ dpc-459 135 17 clark clark NOUN dpc-459 135 18 ? ? PUNCT dpc-459 135 19 am be AUX dpc-459 135 20 j j PROPN dpc-459 135 21 dermatopathol dermatopathol NOUN dpc-459 135 22 . . PUNCT dpc-459 136 1 1992 1992 NUM dpc-459 136 2 oct;14(5):447 oct;14(5):447 NUM dpc-459 136 3 - - PUNCT dpc-459 136 4 453 453 NUM dpc-459 136 5 . . NOUN dpc-459 137 1 10 10 NUM dpc-459 137 2 . . PUNCT dpc-459 138 1 miller miller PROPN dpc-459 138 2 aj aj PROPN dpc-459 138 3 , , PUNCT dpc-459 138 4 mihm mihm PROPN dpc-459 138 5 mc mc PROPN dpc-459 138 6 jr jr PROPN dpc-459 138 7 . . PUNCT dpc-459 139 1 melanoma melanoma PROPN dpc-459 139 2 . . PUNCT dpc-459 140 1 n n PRON dpc-459 140 2 engl engl PROPN dpc-459 140 3 j j PROPN dpc-459 140 4 med med PROPN dpc-459 140 5 . . PUNCT dpc-459 141 1 2006 2006 NUM dpc-459 141 2 jul jul PROPN dpc-459 141 3 6;355(1):51 6;355(1):51 PROPN dpc-459 141 4 - - PUNCT dpc-459 141 5 65 65 NUM dpc-459 141 6 . . PUNCT dpc-459 142 1 11 11 NUM dpc-459 142 2 . . PUNCT dpc-459 143 1 clark clark PROPN dpc-459 143 2 wh wh PROPN dpc-459 143 3 jr jr PROPN dpc-459 143 4 , , PUNCT dpc-459 143 5 reimer reimer PROPN dpc-459 143 6 rr rr PROPN dpc-459 143 7 , , PUNCT dpc-459 143 8 greene greene PROPN dpc-459 143 9 m m PROPN dpc-459 143 10 , , PUNCT dpc-459 143 11 ainsworth ainsworth PROPN dpc-459 143 12 am am PROPN dpc-459 143 13 , , PUNCT dpc-459 143 14 mastrangelo mastrangelo PROPN dpc-459 143 15 mj mj PROPN dpc-459 143 16 . . PROPN dpc-459 143 17 origin origin PROPN dpc-459 143 18 of of ADP dpc-459 143 19 familial familial ADJ dpc-459 143 20 malignant malignant ADJ dpc-459 143 21 melanomas melanomas NOUN dpc-459 143 22 from from ADP dpc-459 143 23 heritable heritable ADJ dpc-459 143 24 melanocytic melanocytic ADJ dpc-459 143 25 lesions lesion NOUN dpc-459 143 26 . . PUNCT dpc-459 144 1 ‘ ' PUNCT dpc-459 144 2 the the DET dpc-459 144 3 b b PROPN dpc-459 144 4 - - PUNCT dpc-459 144 5 k k ADJ dpc-459 144 6 molesyndrome molesyndrome NOUN dpc-459 144 7 ’ ' PUNCT dpc-459 144 8 . . PUNCT dpc-459 145 1 arch arch ADJ dpc-459 145 2 dermatol dermatol NOUN dpc-459 145 3 . . PUNCT dpc-459 146 1 1978 1978 NUM dpc-459 146 2 may;114(5):732 may;114(5):732 NOUN dpc-459 146 3 - - NOUN dpc-459 146 4 738 738 NUM dpc-459 146 5 . . PUNCT